| UniProt: | P43674 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13133 | ||
| Length: | 254 (234) | ||
| Sequences: | 1612 | ||
| Seq/Len: | 6.89 |
| YCAL
Paralog alert: 0.68 [within 20: 0.01] - ratio of genomes with paralogs Cluster includes: LOIP YCAL |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 76_R | 125_D | 4.282 | 1.00 | |
| 231_S | 241_E | 3.456 | 1.00 | |
| 84_L | 136_L | 3.219 | 1.00 | |
| 115_V | 128_I | 3.053 | 1.00 | |
| 127_E | 220_T | 2.875 | 1.00 | |
| 81_A | 95_Y | 2.733 | 1.00 | |
| 107_A | 139_V | 2.246 | 1.00 | |
| 127_E | 216_G | 2.209 | 1.00 | |
| 219_E | 247_R | 2.152 | 1.00 | |
| 115_V | 132_L | 2.144 | 1.00 | |
| 49_A | 53_A | 2.118 | 1.00 | |
| 141_L | 199_F | 2.113 | 1.00 | |
| 130_G | 214_L | 2.027 | 1.00 | |
| 216_G | 219_E | 1.949 | 1.00 | |
| 215_V | 246_I | 1.909 | 1.00 | |
| 198_D | 245_H | 1.878 | 1.00 | |
| 124_N | 127_E | 1.859 | 1.00 | |
| 98_Y | 114_R | 1.843 | 1.00 | |
| 94_N | 112_C | 1.807 | 1.00 | |
| 123_M | 217_S | 1.807 | 1.00 | |
| 194_S | 245_H | 1.798 | 1.00 | |
| 140_A | 203_L | 1.774 | 1.00 | |
| 194_S | 241_E | 1.726 | 1.00 | |
| 77_L | 115_V | 1.724 | 1.00 | |
| 57_C | 114_R | 1.701 | 1.00 | |
| 215_V | 247_R | 1.692 | 1.00 | |
| 246_I | 250_I | 1.666 | 1.00 | |
| 49_A | 142_G | 1.636 | 1.00 | |
| 147_E | 192_K | 1.614 | 1.00 | |
| 215_V | 250_I | 1.579 | 1.00 | |
| 126_N | 213_G | 1.558 | 1.00 | |
| 191_D | 194_S | 1.557 | 1.00 | |
| 102_D | 116_Y | 1.555 | 0.99 | |
| 127_E | 213_G | 1.552 | 0.99 | |
| 130_G | 213_G | 1.542 | 0.99 | |
| 124_N | 213_G | 1.539 | 0.99 | |
| 106_W | 114_R | 1.539 | 0.99 | |
| 81_A | 113_V | 1.519 | 0.99 | |
| 119_L | 131_V | 1.502 | 0.99 | |
| 36_L | 146_A | 1.5 | 0.99 | |
| 100_T | 116_Y | 1.475 | 0.99 | |
| 222_A | 240_T | 1.475 | 0.99 | |
| 57_C | 96_K | 1.472 | 0.99 | |
| 99_M | 117_S | 1.468 | 0.99 | |
| 77_L | 128_I | 1.458 | 0.99 | |
| 73_Y | 97_V | 1.451 | 0.99 | |
| 119_L | 127_E | 1.409 | 0.99 | |
| 142_G | 145_L | 1.386 | 0.99 | |
| 212_Q | 250_I | 1.385 | 0.99 | |
| 80_I | 128_I | 1.379 | 0.99 | |
| 53_A | 108_M | 1.379 | 0.99 | |
| 199_F | 203_L | 1.373 | 0.98 | |
| 59_E | 63_G | 1.361 | 0.98 | |
| 186_A | 189_S | 1.341 | 0.98 | |
| 81_A | 85_G | 1.338 | 0.98 | |
| 202_D | 206_K | 1.322 | 0.98 | |
| 36_L | 40_K | 1.296 | 0.98 | |
| 126_N | 209_I | 1.293 | 0.97 | |
| 161_I | 165_S | 1.288 | 0.97 | |
| 239_S | 243_A | 1.279 | 0.97 | |
| 245_H | 249_R | 1.274 | 0.97 | |
| 143_H | 195_E | 1.269 | 0.97 | |
| 123_M | 128_I | 1.268 | 0.97 | |
| 60_M | 98_Y | 1.265 | 0.97 | |
| 57_C | 61_D | 1.23 | 0.96 | |
| 81_A | 136_L | 1.214 | 0.96 | |
| 121_D | 127_E | 1.213 | 0.96 | |
| 45_S | 48_D | 1.211 | 0.96 | |
| 95_Y | 98_Y | 1.21 | 0.96 | |
| 95_Y | 99_M | 1.204 | 0.96 | |
| 230_Q | 233_F | 1.198 | 0.96 | |
| 128_I | 132_L | 1.171 | 0.95 | |
| 133_G | 200_S | 1.159 | 0.94 | |
| 51_A | 55_Q | 1.158 | 0.94 | |
| 137_G | 140_A | 1.149 | 0.94 | |
| 78_A | 82_K | 1.147 | 0.94 | |
| 245_H | 248_D | 1.144 | 0.94 | |
| 50_K | 54_N | 1.128 | 0.93 | |
| 59_E | 62_S | 1.127 | 0.93 | |
| 95_Y | 113_V | 1.126 | 0.93 | |
| 103_V | 116_Y | 1.121 | 0.93 | |
| 129_E | 209_I | 1.117 | 0.93 | |
| 186_A | 235_S | 1.115 | 0.93 | |
| 140_A | 199_F | 1.114 | 0.93 | |
| 29_N | 33_S | 1.109 | 0.93 | |
| 15_A | 18_T | 1.107 | 0.92 | |
| 29_N | 32_I | 1.101 | 0.92 | |
| 216_G | 220_T | 1.097 | 0.92 | |
| 75_K | 79_K | 1.096 | 0.92 | |
| 48_D | 51_A | 1.095 | 0.92 | |
| 147_E | 150_A | 1.094 | 0.92 | |
| 109_A | 144_S | 1.09 | 0.92 | |
| 53_A | 110_N | 1.088 | 0.92 | |
| 84_L | 203_L | 1.082 | 0.91 | |
| 115_V | 119_L | 1.076 | 0.91 | |
| 71_S | 75_K | 1.072 | 0.91 | |
| 219_E | 243_A | 1.064 | 0.90 | |
| 65_Q | 99_M | 1.064 | 0.90 | |
| 137_G | 199_F | 1.06 | 0.90 | |
| 30_M | 33_S | 1.056 | 0.90 | |
| 212_Q | 247_R | 1.052 | 0.90 | |
| 200_S | 214_L | 1.047 | 0.89 | |
| 80_I | 209_I | 1.046 | 0.89 | |
| 81_A | 125_D | 1.044 | 0.89 | |
| 17_L | 20_C | 1.041 | 0.89 | |
| 217_S | 239_S | 1.031 | 0.88 | |
| 149_K | 153_A | 1.029 | 0.88 | |
| 198_D | 249_R | 1.028 | 0.88 | |
| 126_N | 210_S | 1.027 | 0.88 | |
| 113_V | 132_L | 1.023 | 0.88 | |
| 144_S | 147_E | 1.023 | 0.88 | |
| 207_R | 211_T | 1.022 | 0.88 | |
| 15_A | 19_G | 1.022 | 0.88 | |
| 56_G | 59_E | 1.018 | 0.88 | |
| 200_S | 207_R | 1.017 | 0.88 | |
| 107_A | 123_M | 1.014 | 0.87 | |
| 110_N | 129_E | 1.009 | 0.87 | |
| 67_A | 117_S | 1.009 | 0.87 | |
| 201_F | 250_I | 1.004 | 0.87 | |
| 222_A | 243_A | 1.003 | 0.87 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3c37A | 2 | 0.8661 | 100 | 0.339 | Contact Map | 0.666 |
| 4aw6A | 4 | 0.9291 | 100 | 0.586 | Contact Map | 0.582 |
| 4il3A | 2 | 0.9213 | 100 | 0.598 | Contact Map | 0.618 |
| 3cqbA | 2 | 0.4016 | 99.6 | 0.761 | Contact Map | 0.585 |
| 4jixA | 2 | 0.4213 | 89.8 | 0.925 | Contact Map | 0.604 |
| 3dteA | 1 | 0.7008 | 88.6 | 0.926 | Contact Map | 0.402 |
| 4jiuA | 1 | 0.3819 | 64.3 | 0.941 | Contact Map | 0.602 |
| 1c7kA | 1 | 0.4882 | 47.3 | 0.947 | Contact Map | 0.289 |
| 2w3zA | 1 | 0.9409 | 29.9 | 0.953 | Contact Map | 0.167 |
| 3zbiC | 14 | 0.1772 | 15.7 | 0.959 | Contact Map | 0.371 |
Sequence Conservation (Image Generated using WebLogo v3)