| UniProt: | P39832 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12368 | ||
| Length: | 261 (254) | ||
| Sequences: | 2496 | ||
| Seq/Len: | 9.83 |
| ZNUB
Paralog alert: 0.55 [within 20: 0.16] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 12_G | 225_V | 3.518 | 1.00 | |
| 206_F | 254_S | 3.134 | 1.00 | |
| 128_I | 132_I | 2.996 | 1.00 | |
| 216_V | 220_V | 2.77 | 1.00 | |
| 209_T | 212_Q | 2.566 | 1.00 | |
| 215_G | 219_L | 2.465 | 1.00 | |
| 11_A | 122_V | 2.45 | 1.00 | |
| 224_A | 250_L | 2.444 | 1.00 | |
| 227_G | 246_C | 2.313 | 1.00 | |
| 207_A | 212_Q | 2.296 | 1.00 | |
| 23_G | 200_A | 2.282 | 1.00 | |
| 140_I | 171_L | 2.17 | 1.00 | |
| 14_M | 131_A | 2.15 | 1.00 | |
| 92_S | 248_A | 2.112 | 1.00 | |
| 207_A | 213_M | 2.077 | 1.00 | |
| 202_T | 220_V | 2.043 | 1.00 | |
| 207_A | 216_V | 2.029 | 1.00 | |
| 49_G | 59_A | 2.017 | 1.00 | |
| 164_K | 167_R | 1.982 | 1.00 | |
| 237_T | 242_S | 1.959 | 1.00 | |
| 84_T | 201_A | 1.958 | 1.00 | |
| 231_F | 246_C | 1.955 | 1.00 | |
| 202_T | 254_S | 1.828 | 1.00 | |
| 16_A | 225_V | 1.787 | 1.00 | |
| 135_V | 139_A | 1.787 | 1.00 | |
| 3_E | 6_F | 1.771 | 1.00 | |
| 224_A | 247_A | 1.754 | 1.00 | |
| 151_M | 165_L | 1.703 | 1.00 | |
| 204_R | 213_M | 1.702 | 1.00 | |
| 99_V | 245_L | 1.687 | 1.00 | |
| 14_M | 134_V | 1.631 | 1.00 | |
| 21_P | 138_V | 1.63 | 1.00 | |
| 232_S | 239_A | 1.624 | 1.00 | |
| 18_A | 134_V | 1.612 | 1.00 | |
| 194_S | 244_V | 1.608 | 1.00 | |
| 11_A | 130_I | 1.602 | 1.00 | |
| 202_T | 250_L | 1.563 | 1.00 | |
| 203_A | 216_V | 1.542 | 1.00 | |
| 140_I | 175_V | 1.535 | 1.00 | |
| 150_S | 157_L | 1.531 | 1.00 | |
| 133_G | 182_V | 1.502 | 1.00 | |
| 11_A | 127_L | 1.487 | 1.00 | |
| 208_R | 212_Q | 1.485 | 1.00 | |
| 249_L | 253_L | 1.48 | 1.00 | |
| 13_I | 222_M | 1.459 | 1.00 | |
| 224_A | 246_C | 1.451 | 1.00 | |
| 220_V | 224_A | 1.447 | 1.00 | |
| 24_S | 213_M | 1.443 | 1.00 | |
| 231_F | 235_Y | 1.426 | 1.00 | |
| 129_S | 132_I | 1.424 | 1.00 | |
| 223_V | 227_G | 1.422 | 1.00 | |
| 44_L | 97_G | 1.417 | 1.00 | |
| 215_G | 218_V | 1.416 | 1.00 | |
| 61_I | 178_L | 1.387 | 0.99 | |
| 5_L | 233_A | 1.37 | 0.99 | |
| 41_A | 67_L | 1.354 | 0.99 | |
| 148_L | 172_L | 1.347 | 0.99 | |
| 17_C | 218_V | 1.347 | 0.99 | |
| 230_T | 234_V | 1.346 | 0.99 | |
| 159_F | 166_Q | 1.345 | 0.99 | |
| 145_W | 214_A | 1.342 | 0.99 | |
| 29_R | 152_T | 1.324 | 0.99 | |
| 202_T | 247_A | 1.31 | 0.99 | |
| 229_L | 239_A | 1.303 | 0.99 | |
| 10_L | 127_L | 1.297 | 0.99 | |
| 94_L | 190_L | 1.291 | 0.99 | |
| 157_L | 161_D | 1.285 | 0.99 | |
| 126_D | 185_K | 1.282 | 0.99 | |
| 238_P | 241_P | 1.281 | 0.99 | |
| 181_G | 190_L | 1.27 | 0.99 | |
| 140_I | 148_L | 1.27 | 0.99 | |
| 36_D | 40_H | 1.269 | 0.99 | |
| 219_L | 223_V | 1.259 | 0.99 | |
| 158_A | 165_L | 1.253 | 0.99 | |
| 163_V | 168_V | 1.25 | 0.98 | |
| 132_I | 136_I | 1.213 | 0.98 | |
| 145_W | 211_E | 1.212 | 0.98 | |
| 76_K | 166_Q | 1.205 | 0.98 | |
| 12_G | 119_L | 1.2 | 0.98 | |
| 7_P | 124_P | 1.19 | 0.98 | |
| 24_S | 214_A | 1.179 | 0.98 | |
| 13_I | 226_T | 1.177 | 0.98 | |
| 144_Q | 147_N | 1.176 | 0.98 | |
| 136_I | 139_A | 1.173 | 0.97 | |
| 69_G | 174_L | 1.171 | 0.97 | |
| 144_Q | 168_V | 1.161 | 0.97 | |
| 148_L | 151_M | 1.16 | 0.97 | |
| 167_R | 171_L | 1.158 | 0.97 | |
| 29_R | 155_P | 1.145 | 0.97 | |
| 51_L | 100_V | 1.131 | 0.97 | |
| 4_L | 8_G | 1.128 | 0.97 | |
| 36_D | 90_A | 1.103 | 0.96 | |
| 65_L | 174_L | 1.1 | 0.96 | |
| 16_A | 222_M | 1.097 | 0.96 | |
| 250_L | 254_S | 1.093 | 0.96 | |
| 47_A | 101_V | 1.091 | 0.96 | |
| 72_V | 173_M | 1.08 | 0.95 | |
| 202_T | 205_R | 1.068 | 0.95 | |
| 144_Q | 171_L | 1.066 | 0.95 | |
| 80_L | 251_F | 1.058 | 0.95 | |
| 124_P | 128_I | 1.057 | 0.95 | |
| 25_F | 145_W | 1.054 | 0.94 | |
| 29_R | 169_K | 1.052 | 0.94 | |
| 155_P | 169_K | 1.052 | 0.94 | |
| 102_S | 238_P | 1.046 | 0.94 | |
| 9_W | 226_T | 1.046 | 0.94 | |
| 212_Q | 215_G | 1.043 | 0.94 | |
| 125_E | 128_I | 1.04 | 0.94 | |
| 253_L | 256_M | 1.039 | 0.94 | |
| 131_A | 135_V | 1.039 | 0.94 | |
| 43_L | 97_G | 1.038 | 0.94 | |
| 144_Q | 172_L | 1.037 | 0.94 | |
| 96_L | 99_V | 1.035 | 0.94 | |
| 122_V | 186_F | 1.032 | 0.94 | |
| 118_D | 241_P | 1.022 | 0.93 | |
| 220_V | 250_L | 1.021 | 0.93 | |
| 5_L | 239_A | 1.021 | 0.93 | |
| 228_G | 243_V | 1.02 | 0.93 | |
| 26_V | 33_Y | 1.017 | 0.93 | |
| 203_A | 220_V | 1.007 | 0.92 | |
| 205_R | 254_S | 1.003 | 0.92 | |
| 148_L | 168_V | 1 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 4g1uA | 2 | 0.9885 | 100 | 0.527 | Contact Map | 0.496 |
| 2nq2A | 2 | 0.9885 | 100 | 0.528 | Contact Map | 0.574 |
| 2qi9A | 2 | 0.977 | 100 | 0.529 | Contact Map | 0.518 |
| 2zy9A | 2 | 0.3793 | 29.6 | 0.95 | Contact Map | 0.547 |
| 4b19A | 1 | 0.1149 | 3.6 | 0.967 | Contact Map | |
| 1rklA | 1 | 0.1379 | 3.5 | 0.968 | Contact Map | 0.231 |
| 2latA | 1 | 0.1418 | 2.5 | 0.97 | Contact Map | 0.405 |
| 2l2tA | 2 | 0.1648 | 2.3 | 0.97 | Contact Map | 0.157 |
| 1jb0M | 1 | 0.1188 | 2 | 0.972 | Contact Map | 0.322 |
| 2kv5A | 1 | 0.1264 | 1.8 | 0.972 | Contact Map |
Sequence Conservation (Image Generated using WebLogo v3)