| UniProt: | P38506 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12372 | ||
| Length: | 251 (247) | ||
| Sequences: | 2076 | ||
| Seq/Len: | 8.40 |
| XNI
Paralog alert: 0.36 [within 20: 0.00] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 206_N | 209_A | 5.048 | 1.00 | |
| 150_D | 153_F | 3.852 | 1.00 | |
| 108_A | 234_L | 3.716 | 1.00 | |
| 183_A | 221_H | 3.038 | 1.00 | |
| 222_K | 226_F | 3.017 | 1.00 | |
| 216_K | 220_T | 2.914 | 1.00 | |
| 161_Q | 164_Q | 2.858 | 1.00 | |
| 115_T | 135_S | 2.664 | 1.00 | |
| 62_R | 230_D | 2.652 | 1.00 | |
| 221_H | 224_M | 2.635 | 1.00 | |
| 215_R | 219_E | 2.468 | 1.00 | |
| 204_Y | 226_F | 2.413 | 1.00 | |
| 213_K | 217_K | 2.406 | 1.00 | |
| 85_R | 97_S | 2.319 | 1.00 | |
| 204_Y | 222_K | 2.238 | 1.00 | |
| 201_E | 226_F | 2.169 | 1.00 | |
| 243_N | 246_Q | 2.156 | 1.00 | |
| 213_K | 216_K | 2.11 | 1.00 | |
| 202_G | 205_E | 2.076 | 1.00 | |
| 168_Y | 194_L | 2.047 | 1.00 | |
| 4_H | 120_Q | 2.021 | 1.00 | |
| 155_D | 161_Q | 2.014 | 1.00 | |
| 10_A | 47_A | 1.964 | 1.00 | |
| 89_E | 95_C | 1.946 | 1.00 | |
| 15_R | 19_A | 1.937 | 1.00 | |
| 199_S | 202_G | 1.93 | 1.00 | |
| 112_V | 236_T | 1.87 | 1.00 | |
| 86_A | 89_E | 1.864 | 1.00 | |
| 185_I | 214_W | 1.853 | 1.00 | |
| 35_Q | 39_H | 1.85 | 1.00 | |
| 204_Y | 207_L | 1.843 | 1.00 | |
| 30_Q | 87_A | 1.824 | 1.00 | |
| 152_P | 155_D | 1.816 | 1.00 | |
| 151_A | 163_Q | 1.816 | 1.00 | |
| 196_E | 209_A | 1.799 | 1.00 | |
| 18_H | 76_E | 1.796 | 1.00 | |
| 201_E | 229_R | 1.781 | 1.00 | |
| 152_P | 156_K | 1.735 | 1.00 | |
| 184_G | 217_K | 1.692 | 1.00 | |
| 54_R | 61_Q | 1.687 | 1.00 | |
| 179_V | 232_A | 1.673 | 1.00 | |
| 182_V | 218_L | 1.662 | 1.00 | |
| 111_A | 138_L | 1.628 | 1.00 | |
| 17_I | 32_A | 1.627 | 1.00 | |
| 168_Y | 172_A | 1.565 | 1.00 | |
| 136_P | 151_A | 1.563 | 1.00 | |
| 172_A | 187_P | 1.533 | 1.00 | |
| 160_V | 191_T | 1.522 | 1.00 | |
| 108_A | 236_T | 1.521 | 1.00 | |
| 112_V | 116_Q | 1.515 | 1.00 | |
| 197_F | 210_V | 1.513 | 1.00 | |
| 202_G | 206_N | 1.501 | 1.00 | |
| 107_A | 123_I | 1.487 | 1.00 | |
| 197_F | 206_N | 1.477 | 1.00 | |
| 192_Q | 196_E | 1.476 | 1.00 | |
| 166_P | 233_R | 1.462 | 0.99 | |
| 151_A | 155_D | 1.46 | 0.99 | |
| 182_V | 225_A | 1.46 | 0.99 | |
| 73_M | 78_H | 1.452 | 0.99 | |
| 128_K | 169_W | 1.433 | 0.99 | |
| 197_F | 209_A | 1.426 | 0.99 | |
| 36_L | 124_V | 1.425 | 0.99 | |
| 204_Y | 225_A | 1.407 | 0.99 | |
| 46_V | 247_L | 1.364 | 0.99 | |
| 229_R | 233_R | 1.356 | 0.99 | |
| 75_E | 78_H | 1.342 | 0.99 | |
| 44_H | 119_H | 1.325 | 0.99 | |
| 63_L | 231_I | 1.324 | 0.99 | |
| 204_Y | 218_L | 1.321 | 0.99 | |
| 207_L | 215_R | 1.296 | 0.98 | |
| 170_G | 232_A | 1.288 | 0.98 | |
| 210_V | 218_L | 1.286 | 0.98 | |
| 115_T | 137_T | 1.277 | 0.98 | |
| 53_N | 99_S | 1.266 | 0.98 | |
| 131_C | 140_I | 1.265 | 0.98 | |
| 98_T | 106_L | 1.246 | 0.98 | |
| 30_Q | 84_L | 1.24 | 0.98 | |
| 167_D | 229_R | 1.236 | 0.98 | |
| 217_K | 220_T | 1.229 | 0.98 | |
| 139_R | 148_W | 1.217 | 0.97 | |
| 201_E | 205_E | 1.212 | 0.97 | |
| 212_E | 215_R | 1.209 | 0.97 | |
| 191_T | 195_V | 1.208 | 0.97 | |
| 154_I | 160_V | 1.207 | 0.97 | |
| 183_A | 224_M | 1.194 | 0.97 | |
| 14_I | 84_L | 1.192 | 0.97 | |
| 207_L | 219_E | 1.19 | 0.97 | |
| 101_N | 238_L | 1.19 | 0.97 | |
| 4_H | 122_T | 1.175 | 0.97 | |
| 14_I | 77_L | 1.173 | 0.96 | |
| 168_Y | 187_P | 1.168 | 0.96 | |
| 171_L | 189_S | 1.167 | 0.96 | |
| 54_R | 60_H | 1.163 | 0.96 | |
| 189_S | 192_Q | 1.145 | 0.96 | |
| 125_S | 130_Y | 1.136 | 0.96 | |
| 134_L | 140_I | 1.135 | 0.96 | |
| 69_G | 178_K | 1.133 | 0.95 | |
| 25_C | 84_L | 1.122 | 0.95 | |
| 101_N | 235_Q | 1.114 | 0.95 | |
| 230_D | 235_Q | 1.098 | 0.94 | |
| 160_V | 164_Q | 1.097 | 0.94 | |
| 57_G | 60_H | 1.094 | 0.94 | |
| 62_R | 227_L | 1.093 | 0.94 | |
| 109_T | 238_L | 1.064 | 0.93 | |
| 196_E | 211_A | 1.055 | 0.93 | |
| 179_V | 228_C | 1.046 | 0.92 | |
| 134_L | 154_I | 1.042 | 0.92 | |
| 51_D | 99_S | 1.041 | 0.92 | |
| 219_E | 222_K | 1.04 | 0.92 | |
| 15_R | 73_M | 1.034 | 0.92 | |
| 5_L | 247_L | 1.028 | 0.91 | |
| 115_T | 138_L | 1.027 | 0.91 | |
| 6_L | 124_V | 1.024 | 0.91 | |
| 106_L | 110_L | 1.013 | 0.91 | |
| 216_K | 219_E | 1.011 | 0.90 | |
| 113_K | 117_A | 1.006 | 0.90 | |
| 212_E | 216_K | 1.002 | 0.90 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1bgxT | 1 | 0.9761 | 100 | 0.176 | Contact Map | 0.345 |
| 3zdbA | 1 | 1 | 100 | 0.177 | Contact Map | 0.73 |
| 1exnA | 2 | 0.988 | 100 | 0.203 | Contact Map | 0.586 |
| 3h7iA | 1 | 0.9363 | 100 | 0.28 | Contact Map | 0.396 |
| 2izoA | 1 | 0.9124 | 100 | 0.401 | Contact Map | 0.498 |
| 3oryA | 1 | 0.8924 | 100 | 0.413 | Contact Map | 0.428 |
| 1rxwA | 1 | 0.8884 | 100 | 0.413 | Contact Map | 0.585 |
| 3q8kA | 1 | 0.9203 | 100 | 0.444 | Contact Map | 0.438 |
| 1a76A | 1 | 0.8645 | 100 | 0.448 | Contact Map | 0.477 |
| 1ul1X | 3 | 0.9203 | 100 | 0.449 | Contact Map | 0.452 |
Sequence Conservation (Image Generated using WebLogo v3)