May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org

NRFE - Cytochrome c-type biogenesis protein NrfE
UniProt: P32710 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11948
Length: 552 (547)
Sequences: 684
Seq/Len: 1.25

NRFE
Paralog alert: 0.46 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: CCMF NRFE
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
47_S 67_K 3.999 1.00
166_L 238_A 3.836 1.00
45_L 68_L 3.606 1.00
53_Y 74_G 3.51 1.00
206_I 533_G 3.327 1.00
41_T 71_V 3.242 1.00
64_W 68_L 3.102 1.00
431_L 435_Q 2.937 1.00
215_E 492_E 2.841 1.00
447_E 465_A 2.739 1.00
34_L 84_L 2.712 1.00
121_L 125_L 2.628 1.00
60_S 139_E 2.585 1.00
237_S 265_T 2.462 1.00
45_L 64_W 2.428 0.99
118_A 300_L 2.422 0.99
3_T 29_Q 2.349 0.99
461_K 479_E 2.348 0.99
4_P 114_L 2.27 0.99
310_A 314_W 2.259 0.99
203_A 537_I 2.155 0.98
419_V 525_G 2.153 0.98
42_Y 46_I 2.152 0.98
497_W 527_R 2.134 0.98
333_L 394_V 2.134 0.98
433_P 446_F 2.12 0.98
66_L 150_P 2.12 0.98
57_H 74_G 2.114 0.98
445_R 467_F 2.093 0.98
476_L 494_S 2.033 0.97
438_T 443_T 2.009 0.97
464_V 505_A 2.003 0.97
244_S 338_L 1.934 0.96
62_L 70_A 1.928 0.96
166_L 265_T 1.896 0.96
478_P 494_S 1.891 0.96
28_A 32_L 1.87 0.95
420_S 533_G 1.849 0.95
464_V 518_F 1.801 0.94
496_R 501_H 1.773 0.93
232_L 381_G 1.771 0.93
112_L 171_S 1.754 0.93
463_I 475_E 1.697 0.91
8_F 110_A 1.661 0.90
37_F 84_L 1.648 0.89
385_L 414_A 1.637 0.89
37_F 71_V 1.599 0.87
438_T 441_G 1.596 0.87
62_L 74_G 1.593 0.87
273_T 297_L 1.592 0.87
61_L 139_E 1.592 0.87
436_Q 445_R 1.585 0.87
359_G 365_R 1.578 0.86
440_A 522_V 1.575 0.86
412_L 535_L 1.556 0.85
344_V 377_T 1.552 0.85
205_I 231_S 1.543 0.85
354_Y 372_Y 1.529 0.84
69_A 152_L 1.508 0.83
238_A 265_T 1.506 0.83
195_L 242_L 1.499 0.82
30_F 88_A 1.497 0.82
375_R 379_P 1.493 0.82
27_L 91_A 1.492 0.82
37_F 41_T 1.489 0.82
142_D 486_R 1.487 0.82
27_L 94_A 1.487 0.82
41_T 45_L 1.487 0.82
110_A 114_L 1.48 0.81
30_F 91_A 1.468 0.80
354_Y 358_Y 1.468 0.80
108_T 172_V 1.466 0.80
206_I 420_S 1.445 0.79
431_L 436_Q 1.438 0.78
53_Y 62_L 1.432 0.78
444_F 464_V 1.431 0.78
160_Y 164_G 1.413 0.77
210_W 502_D 1.391 0.75
237_S 345_L 1.39 0.75
163_Y 276_V 1.382 0.74
43_C 46_I 1.378 0.74
480_R 491_M 1.368 0.73
300_L 304_I 1.366 0.73
5_L 9_A 1.361 0.73
459_S 479_E 1.358 0.73
420_S 424_R 1.349 0.72
44_F 53_Y 1.348 0.72
111_V 311_L 1.34 0.71
314_W 317_R 1.34 0.71
233_L 265_T 1.338 0.71
481_R 492_E 1.333 0.71
408_A 423_S 1.328 0.70
257_W 338_L 1.325 0.70
30_F 34_L 1.319 0.69
112_L 167_M 1.306 0.68
297_L 306_L 1.304 0.68
452_Q 461_K 1.302 0.68
465_A 472_R 1.3 0.68
395_S 399_V 1.3 0.68
436_Q 443_T 1.288 0.67
158_L 203_A 1.284 0.66
499_G 531_G 1.281 0.66
26_I 90_S 1.279 0.66
26_I 29_Q 1.275 0.66
413_F 417_V 1.274 0.66
59_Y 62_L 1.271 0.65
417_V 489_Q 1.271 0.65
265_T 268_L 1.263 0.65
36_A 534_L 1.262 0.64
241_L 262_A 1.245 0.63
444_F 505_A 1.241 0.63
538_A 541_L 1.24 0.62
55_A 133_I 1.235 0.62
47_S 53_Y 1.232 0.62
111_V 174_L 1.227 0.61
70_A 153_I 1.214 0.60
265_T 385_L 1.212 0.60
38_G 303_L 1.205 0.59
13_L 20_R 1.203 0.59
385_L 388_I 1.2 0.59
466_L 476_L 1.195 0.58
33_L 87_S 1.186 0.57
359_G 363_W 1.185 0.57
150_P 154_F 1.185 0.57
379_P 383_L 1.183 0.57
160_Y 257_W 1.183 0.57
467_F 470_Q 1.175 0.56
11_V 19_M 1.174 0.56
233_L 237_S 1.173 0.56
2_L 18_M 1.173 0.56
81_L 275_I 1.17 0.56
158_L 520_L 1.169 0.56
9_A 386_V 1.164 0.55
450_D 463_I 1.158 0.55
139_E 512_G 1.153 0.54
450_D 461_K 1.153 0.54
426_E 521_Y 1.151 0.54
347_I 376_A 1.151 0.54
150_P 300_L 1.149 0.54
43_C 84_L 1.149 0.54
70_A 74_G 1.148 0.54
64_W 88_A 1.148 0.54
448_C 462_A 1.147 0.54
354_Y 379_P 1.146 0.53
93_F 172_V 1.144 0.53
3_T 25_G 1.14 0.53
297_L 301_F 1.138 0.53
13_L 349_L 1.136 0.53
215_E 490_M 1.136 0.53
79_L 212_A 1.135 0.52
171_S 366_L 1.134 0.52
199_S 540_A 1.134 0.52
4_P 110_A 1.133 0.52
53_Y 59_Y 1.13 0.52
69_A 154_F 1.124 0.51
466_L 503_W 1.123 0.51
248_T 258_S 1.122 0.51
466_L 473_I 1.119 0.51
249_R 255_C 1.118 0.51
410_V 504_Y 1.117 0.51
139_E 303_L 1.116 0.51
245_L 334_I 1.113 0.50
142_D 506_V 1.111 0.50
244_S 257_W 1.105 0.49
394_V 399_V 1.105 0.49
57_H 76_E 1.105 0.49
432_Q 435_Q 1.104 0.49
244_S 258_S 1.1 0.49
30_F 372_Y 1.1 0.49
41_T 68_L 1.098 0.49
59_Y 112_L 1.094 0.48
370_A 375_R 1.093 0.48
327_G 332_M 1.092 0.48
440_A 443_T 1.091 0.48
271_L 353_L 1.091 0.48
150_P 531_G 1.09 0.48
205_I 481_R 1.084 0.47
3_T 90_S 1.083 0.47
463_I 477_T 1.08 0.47
527_R 533_G 1.075 0.47
221_W 403_A 1.073 0.46
104_L 176_S 1.07 0.46
388_I 410_V 1.069 0.46
174_L 308_S 1.063 0.45
195_L 543_S 1.061 0.45
150_P 286_A 1.06 0.45
448_C 463_I 1.06 0.45
438_T 448_C 1.059 0.45
314_W 374_N 1.057 0.45
467_F 472_R 1.056 0.45
18_M 392_T 1.053 0.44
379_P 525_G 1.051 0.44
286_A 513_P 1.049 0.44
482_F 541_L 1.046 0.44
37_F 74_G 1.045 0.44
35_L 471_Q 1.043 0.43
419_V 522_V 1.041 0.43
43_C 51_V 1.037 0.43
81_L 446_F 1.034 0.43
498_N 528_W 1.03 0.42
462_A 491_M 1.028 0.42
447_E 463_I 1.024 0.42
347_I 360_L 1.024 0.42
299_S 302_A 1.021 0.41
430_N 511_T 1.021 0.41
237_S 268_L 1.021 0.41
126_W 289_L 1.019 0.41
160_Y 456_N 1.018 0.41
185_A 286_A 1.018 0.41
62_L 112_L 1.017 0.41
13_L 178_L 1.016 0.41
152_L 522_V 1.016 0.41
357_I 405_V 1.014 0.41
312_Y 509_E 1.013 0.41
146_M 516_Y 1.012 0.40
333_L 462_A 1.011 0.40
498_N 501_H 1.01 0.40
2_L 5_L 1.01 0.40
69_A 289_L 1.01 0.40
5_L 526_V 1.009 0.40
151_G 276_V 1.009 0.40
424_R 523_Q 1.007 0.40
65_E 153_I 1.007 0.40
30_F 280_I 1.006 0.40
38_G 42_Y 1.006 0.40
33_L 71_V 1.005 0.40
534_L 538_A 1.004 0.40
122_F 128_D 1.004 0.40
452_Q 457_Y 1.001 0.39
170_A 266_L 1 0.39
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
3cfuA20.2011110.986Contact Map0.5
3qbgA30.10697.50.987Contact Map0.273
3riqA10.18665.30.988Contact Map0
2zpmA10.15944.80.988Contact Map0.241
1q90R10.08884.50.989Contact Map0
3ug9A10.15764.10.989Contact Map0.223
3mcbA10.09422.60.99Contact Map0.272
3mceA40.10692.40.99Contact Map0.302
4m1uB50.09962.20.99Contact Map0.249
1r4pB50.09962.20.99Contact Map0.25

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0376 seconds.