| UniProt: | P28635 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11504 | ||
| Length: | 271 (264) | ||
| Sequences: | 1606 | ||
| Seq/Len: | 6.08 |
| METQ
Paralog alert: 0.59 [within 20: 0.07] - ratio of genomes with paralogs Cluster includes: METQ NLPA |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 156_K | 172_E | 4.142 | 1.00 | |
| 34_K | 64_V | 3.289 | 1.00 | |
| 131_S | 197_A | 3.266 | 1.00 | |
| 121_I | 128_Q | 3.126 | 1.00 | |
| 102_K | 235_E | 3.118 | 1.00 | |
| 253_D | 257_E | 3.087 | 1.00 | |
| 89_K | 93_D | 2.984 | 1.00 | |
| 36_G | 81_I | 2.96 | 1.00 | |
| 132_Q | 180_V | 2.955 | 1.00 | |
| 257_E | 261_K | 2.829 | 1.00 | |
| 134_A | 196_I | 2.757 | 1.00 | |
| 52_V | 254_E | 2.731 | 1.00 | |
| 234_R | 237_N | 2.705 | 1.00 | |
| 129_D | 176_N | 2.612 | 1.00 | |
| 133_V | 198_L | 2.444 | 1.00 | |
| 107_G | 247_V | 2.432 | 1.00 | |
| 96_L | 101_Y | 2.429 | 1.00 | |
| 132_Q | 178_K | 2.402 | 1.00 | |
| 54_K | 60_D | 2.379 | 1.00 | |
| 237_N | 240_A | 2.299 | 1.00 | |
| 94_Q | 98_D | 2.293 | 1.00 | |
| 106_V | 243_V | 2.259 | 1.00 | |
| 128_Q | 131_S | 2.254 | 1.00 | |
| 122_K | 126_E | 2.21 | 1.00 | |
| 95_Q | 101_Y | 2.203 | 1.00 | |
| 119_K | 192_D | 2.197 | 1.00 | |
| 147_L | 150_Q | 2.102 | 1.00 | |
| 136_P | 145_S | 2.072 | 1.00 | |
| 34_K | 62_E | 2.055 | 1.00 | |
| 167_V | 181_E | 2.005 | 1.00 | |
| 103_L | 232_V | 1.999 | 1.00 | |
| 48_V | 255_V | 1.991 | 1.00 | |
| 32_H | 60_D | 1.942 | 1.00 | |
| 135_V | 142_L | 1.894 | 1.00 | |
| 257_E | 260_N | 1.844 | 1.00 | |
| 79_G | 234_R | 1.83 | 1.00 | |
| 77_S | 102_K | 1.827 | 1.00 | |
| 32_H | 62_E | 1.816 | 1.00 | |
| 244_K | 248_Q | 1.806 | 1.00 | |
| 133_V | 177_L | 1.765 | 1.00 | |
| 170_V | 179_I | 1.718 | 1.00 | |
| 56_K | 245_K | 1.696 | 1.00 | |
| 104_V | 235_E | 1.694 | 1.00 | |
| 116_G | 198_L | 1.653 | 1.00 | |
| 115_A | 217_G | 1.597 | 0.99 | |
| 151_K | 222_D | 1.554 | 0.99 | |
| 83_A | 233_T | 1.546 | 0.99 | |
| 59_L | 242_N | 1.533 | 0.99 | |
| 127_L | 131_S | 1.525 | 0.99 | |
| 108_N | 228_V | 1.522 | 0.99 | |
| 33_I | 242_N | 1.52 | 0.99 | |
| 231_I | 247_V | 1.519 | 0.99 | |
| 152_V | 219_F | 1.497 | 0.99 | |
| 135_V | 179_I | 1.479 | 0.99 | |
| 83_A | 246_F | 1.458 | 0.99 | |
| 36_G | 76_L | 1.442 | 0.99 | |
| 127_L | 198_L | 1.428 | 0.99 | |
| 70_V | 91_Y | 1.422 | 0.98 | |
| 47_E | 50_Q | 1.419 | 0.98 | |
| 89_K | 105_A | 1.416 | 0.98 | |
| 52_V | 249_A | 1.415 | 0.98 | |
| 74_E | 95_Q | 1.401 | 0.98 | |
| 211_L | 216_D | 1.396 | 0.98 | |
| 212_T | 215_K | 1.393 | 0.98 | |
| 253_D | 256_Y | 1.376 | 0.98 | |
| 59_L | 245_K | 1.369 | 0.98 | |
| 154_L | 177_L | 1.354 | 0.98 | |
| 56_K | 248_Q | 1.342 | 0.98 | |
| 138_D | 141_N | 1.334 | 0.97 | |
| 247_V | 251_Q | 1.33 | 0.97 | |
| 121_I | 197_A | 1.328 | 0.97 | |
| 241_E | 245_K | 1.323 | 0.97 | |
| 52_V | 55_D | 1.315 | 0.97 | |
| 240_A | 243_V | 1.301 | 0.97 | |
| 121_I | 131_S | 1.292 | 0.97 | |
| 239_D | 244_K | 1.287 | 0.97 | |
| 53_A | 59_L | 1.284 | 0.97 | |
| 150_Q | 156_K | 1.282 | 0.97 | |
| 196_I | 199_A | 1.282 | 0.97 | |
| 258_A | 262_V | 1.278 | 0.96 | |
| 74_E | 78_K | 1.253 | 0.96 | |
| 48_V | 52_V | 1.252 | 0.96 | |
| 33_I | 59_L | 1.242 | 0.96 | |
| 37_V | 46_A | 1.232 | 0.95 | |
| 123_S | 126_E | 1.228 | 0.95 | |
| 158_K | 171_V | 1.22 | 0.95 | |
| 156_K | 171_V | 1.22 | 0.95 | |
| 109_T | 247_V | 1.195 | 0.94 | |
| 235_E | 238_K | 1.191 | 0.94 | |
| 115_A | 220_V | 1.186 | 0.94 | |
| 76_L | 81_I | 1.18 | 0.94 | |
| 233_T | 237_N | 1.177 | 0.94 | |
| 182_L | 190_S | 1.177 | 0.94 | |
| 212_T | 216_D | 1.176 | 0.94 | |
| 85_A | 109_T | 1.172 | 0.94 | |
| 96_L | 102_K | 1.171 | 0.93 | |
| 52_V | 255_V | 1.163 | 0.93 | |
| 48_V | 51_K | 1.158 | 0.93 | |
| 157_L | 171_V | 1.144 | 0.92 | |
| 50_Q | 54_K | 1.143 | 0.92 | |
| 159_D | 162_G | 1.142 | 0.92 | |
| 20_L | 23_C | 1.133 | 0.92 | |
| 89_K | 230_L | 1.133 | 0.92 | |
| 124_L | 127_L | 1.132 | 0.92 | |
| 69_Y | 72_P | 1.13 | 0.92 | |
| 42_E | 110_F | 1.128 | 0.92 | |
| 202_N | 229_N | 1.124 | 0.92 | |
| 158_K | 169_D | 1.117 | 0.91 | |
| 104_V | 238_K | 1.116 | 0.91 | |
| 129_D | 175_K | 1.111 | 0.91 | |
| 107_G | 231_I | 1.107 | 0.91 | |
| 44_Q | 262_V | 1.102 | 0.90 | |
| 74_E | 99_R | 1.1 | 0.90 | |
| 85_A | 110_F | 1.096 | 0.90 | |
| 134_A | 190_S | 1.096 | 0.90 | |
| 233_T | 236_D | 1.091 | 0.90 | |
| 37_V | 43_Q | 1.085 | 0.90 | |
| 44_Q | 263_F | 1.084 | 0.89 | |
| 96_L | 103_L | 1.082 | 0.89 | |
| 42_E | 112_Y | 1.079 | 0.89 | |
| 127_L | 133_V | 1.062 | 0.88 | |
| 89_K | 108_N | 1.062 | 0.88 | |
| 48_V | 258_A | 1.049 | 0.87 | |
| 51_K | 54_K | 1.045 | 0.87 | |
| 33_I | 246_F | 1.045 | 0.87 | |
| 83_A | 243_V | 1.034 | 0.86 | |
| 173_N | 177_L | 1.025 | 0.86 | |
| 228_V | 270_G | 1.024 | 0.86 | |
| 161_V | 165_P | 1.012 | 0.85 | |
| 69_Y | 184_A | 1.009 | 0.84 | |
| 43_Q | 65_T | 1 | 0.84 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3ir1A | 6 | 0.8708 | 100 | 0.466 | Contact Map | 0.834 |
| 3up9A | 1 | 0.8893 | 100 | 0.486 | Contact Map | 0.692 |
| 4gotA | 1 | 0.9041 | 100 | 0.493 | Contact Map | 0.857 |
| 4ib2A | 2 | 0.9041 | 100 | 0.494 | Contact Map | 0.868 |
| 1xs5A | 1 | 0.8856 | 100 | 0.505 | Contact Map | 0.884 |
| 4k3fA | 1 | 0.8856 | 100 | 0.509 | Contact Map | 0.857 |
| 3tqwA | 2 | 0.8856 | 100 | 0.511 | Contact Map | 0.842 |
| 3gxaA | 6 | 0.952 | 100 | 0.515 | Contact Map | 0.836 |
| 3k2dA | 2 | 0.8745 | 100 | 0.526 | Contact Map | 0.838 |
| 4ef1A | 2 | 0.8967 | 100 | 0.543 | Contact Map | 0.79 |
Sequence Conservation (Image Generated using WebLogo v3)