| UniProt: | P25531 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11312 | ||
| Length: | 222 (215) | ||
| Sequences: | 1448 | ||
| Seq/Len: | 6.73 |
| YICR
Paralog alert: 0.03 [within 20: 0.01] - ratio of genomes with paralogs Cluster includes: YEES YFJY YICR YKFG |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 39_K | 47_E | 4.724 | 1.00 | |
| 52_F | 61_S | 3.079 | 1.00 | |
| 169_L | 202_V | 2.859 | 1.00 | |
| 111_L | 170_A | 2.844 | 1.00 | |
| 138_R | 158_E | 2.677 | 1.00 | |
| 156_I | 195_C | 2.628 | 1.00 | |
| 62_E | 65_Q | 2.506 | 1.00 | |
| 214_V | 219_R | 2.494 | 1.00 | |
| 129_D | 133_R | 2.41 | 1.00 | |
| 185_K | 216_F | 2.348 | 1.00 | |
| 192_I | 202_V | 2.25 | 1.00 | |
| 101_L | 134_V | 2.123 | 1.00 | |
| 115_L | 118_E | 2.047 | 1.00 | |
| 43_T | 46_K | 1.994 | 1.00 | |
| 123_F | 150_V | 1.973 | 1.00 | |
| 126_I | 134_V | 1.931 | 1.00 | |
| 54_S | 57_G | 1.911 | 1.00 | |
| 40_D | 43_T | 1.809 | 1.00 | |
| 25_V | 46_K | 1.802 | 1.00 | |
| 169_L | 191_I | 1.795 | 1.00 | |
| 102_L | 106_M | 1.786 | 1.00 | |
| 136_T | 162_I | 1.731 | 1.00 | |
| 182_K | 186_L | 1.711 | 1.00 | |
| 116_T | 210_R | 1.707 | 1.00 | |
| 145_L | 165_S | 1.684 | 1.00 | |
| 127_F | 138_R | 1.676 | 1.00 | |
| 120_R | 141_F | 1.639 | 1.00 | |
| 185_K | 221_W | 1.613 | 1.00 | |
| 155_I | 191_I | 1.61 | 1.00 | |
| 105_E | 109_E | 1.565 | 1.00 | |
| 130_S | 146_N | 1.563 | 0.99 | |
| 104_P | 218_E | 1.559 | 0.99 | |
| 122_I | 139_R | 1.546 | 0.99 | |
| 139_R | 142_S | 1.53 | 0.99 | |
| 124_M | 139_R | 1.519 | 0.99 | |
| 189_E | 193_K | 1.517 | 0.99 | |
| 83_I | 87_A | 1.513 | 0.99 | |
| 72_I | 77_F | 1.512 | 0.99 | |
| 123_F | 202_V | 1.504 | 0.99 | |
| 120_R | 142_S | 1.482 | 0.99 | |
| 141_F | 148_V | 1.475 | 0.99 | |
| 33_R | 79_Q | 1.474 | 0.99 | |
| 178_A | 212_E | 1.473 | 0.99 | |
| 193_K | 196_Q | 1.469 | 0.99 | |
| 131_Q | 177_C | 1.444 | 0.99 | |
| 192_I | 196_Q | 1.435 | 0.99 | |
| 118_E | 122_I | 1.418 | 0.99 | |
| 9_M | 41_V | 1.394 | 0.99 | |
| 124_M | 137_H | 1.39 | 0.99 | |
| 159_A | 200_L | 1.39 | 0.99 | |
| 115_L | 124_M | 1.38 | 0.98 | |
| 207_V | 214_V | 1.376 | 0.98 | |
| 216_F | 222_I | 1.368 | 0.98 | |
| 127_F | 162_I | 1.348 | 0.98 | |
| 189_E | 192_I | 1.313 | 0.98 | |
| 25_V | 42_L | 1.313 | 0.98 | |
| 158_E | 161_K | 1.306 | 0.98 | |
| 127_F | 158_E | 1.305 | 0.98 | |
| 42_L | 46_K | 1.299 | 0.97 | |
| 14_M | 78_A | 1.297 | 0.97 | |
| 157_R | 163_N | 1.293 | 0.97 | |
| 29_A | 42_L | 1.289 | 0.97 | |
| 156_I | 198_M | 1.281 | 0.97 | |
| 35_G | 76_K | 1.263 | 0.97 | |
| 41_V | 45_A | 1.252 | 0.97 | |
| 144_T | 151_H | 1.25 | 0.97 | |
| 31_F | 79_Q | 1.23 | 0.96 | |
| 188_T | 205_H | 1.211 | 0.96 | |
| 150_V | 187_I | 1.193 | 0.95 | |
| 118_E | 139_R | 1.188 | 0.95 | |
| 63_Y | 67_S | 1.185 | 0.95 | |
| 159_A | 167_L | 1.183 | 0.95 | |
| 112_Q | 211_G | 1.173 | 0.95 | |
| 144_T | 154_E | 1.166 | 0.94 | |
| 132_H | 166_A | 1.164 | 0.94 | |
| 14_M | 22_L | 1.16 | 0.94 | |
| 22_L | 26_E | 1.157 | 0.94 | |
| 55_L | 86_L | 1.157 | 0.94 | |
| 158_E | 162_I | 1.148 | 0.94 | |
| 25_V | 41_V | 1.143 | 0.94 | |
| 120_R | 138_R | 1.141 | 0.94 | |
| 148_V | 187_I | 1.137 | 0.93 | |
| 13_K | 26_E | 1.137 | 0.93 | |
| 116_T | 209_G | 1.134 | 0.93 | |
| 35_G | 79_Q | 1.132 | 0.93 | |
| 101_L | 107_T | 1.126 | 0.93 | |
| 10_P | 35_G | 1.116 | 0.93 | |
| 114_Q | 137_H | 1.115 | 0.93 | |
| 122_I | 142_S | 1.11 | 0.92 | |
| 192_I | 222_I | 1.102 | 0.92 | |
| 14_M | 19_I | 1.097 | 0.92 | |
| 11_R | 75_A | 1.096 | 0.92 | |
| 108_R | 112_Q | 1.096 | 0.92 | |
| 79_Q | 83_I | 1.084 | 0.91 | |
| 66_F | 77_F | 1.074 | 0.91 | |
| 75_A | 78_A | 1.072 | 0.90 | |
| 126_I | 137_H | 1.07 | 0.90 | |
| 31_F | 83_I | 1.065 | 0.90 | |
| 144_T | 149_E | 1.063 | 0.90 | |
| 216_F | 221_W | 1.06 | 0.90 | |
| 13_K | 17_F | 1.056 | 0.90 | |
| 17_F | 21_A | 1.049 | 0.89 | |
| 67_S | 74_V | 1.048 | 0.89 | |
| 182_K | 185_K | 1.047 | 0.89 | |
| 179_E | 219_R | 1.039 | 0.89 | |
| 123_F | 148_V | 1.036 | 0.88 | |
| 107_T | 168_I | 1.034 | 0.88 | |
| 51_N | 69_V | 1.032 | 0.88 | |
| 194_S | 198_M | 1.032 | 0.88 | |
| 105_E | 218_E | 1.032 | 0.88 | |
| 60_T | 90_Y | 1.029 | 0.88 | |
| 14_M | 30_L | 1.024 | 0.88 | |
| 85_E | 89_R | 1.021 | 0.87 | |
| 15_L | 63_Y | 1.018 | 0.87 | |
| 178_A | 214_V | 1.008 | 0.86 | |
| 34_T | 79_Q | 1.006 | 0.86 | |
| 195_C | 198_M | 1.006 | 0.86 | |
| 32_L | 41_V | 1.003 | 0.86 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2qlcA | 8 | 0.5676 | 100 | 0.41 | Contact Map | 0.815 |
| 1x2iA | 2 | 0.3378 | 98.6 | 0.859 | Contact Map | 0.537 |
| 3c1yA | 2 | 0.3964 | 97.6 | 0.89 | Contact Map | 0.639 |
| 1dgsA | 2 | 0.7928 | 97 | 0.901 | Contact Map | 0.625 |
| 1z00A | 1 | 0.4009 | 96.8 | 0.903 | Contact Map | 0.595 |
| 2owoA | 1 | 0.7793 | 96.6 | 0.905 | Contact Map | 0.636 |
| 2a1jB | 1 | 0.3874 | 96.6 | 0.905 | Contact Map | 0.588 |
| 4bxoA | 1 | 0.4189 | 96.3 | 0.908 | Contact Map | 0.587 |
| 2bgwA | 2 | 0.3739 | 96.2 | 0.909 | Contact Map | 0.677 |
| 1kftA | 1 | 0.3514 | 96.1 | 0.91 | Contact Map | 0.475 |
Sequence Conservation (Image Generated using WebLogo v3)