| UniProt: | P16692 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10725 | ||
| Length: | 252 (246) | ||
| Sequences: | 3638 | ||
| Seq/Len: | 14.79 |
| PHNP
Paralog alert: 0.61 [within 20: 0.01] - ratio of genomes with paralogs Cluster includes: PHNP RBN |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 160_A | 181_P | 4.384 | 1.00 | |
| 182_Q | 216_P | 3.748 | 1.00 | |
| 7_L | 10_T | 3.728 | 1.00 | |
| 151_L | 158_R | 3.54 | 1.00 | |
| 53_I | 152_L | 2.788 | 1.00 | |
| 4_T | 248_E | 2.75 | 1.00 | |
| 217_R | 241_E | 2.75 | 1.00 | |
| 4_T | 45_K | 2.721 | 1.00 | |
| 137_T | 153_E | 2.704 | 1.00 | |
| 135_Q | 153_E | 2.574 | 1.00 | |
| 7_L | 243_G | 2.521 | 1.00 | |
| 180_Q | 214_R | 2.41 | 1.00 | |
| 173_L | 212_V | 2.4 | 1.00 | |
| 210_N | 218_V | 2.365 | 1.00 | |
| 183_V | 219_I | 2.345 | 1.00 | |
| 73_L | 136_V | 2.334 | 1.00 | |
| 174_K | 177_R | 2.307 | 1.00 | |
| 186_M | 201_C | 2.249 | 1.00 | |
| 159_V | 185_V | 2.189 | 1.00 | |
| 45_K | 50_I | 2.155 | 1.00 | |
| 208_A | 212_V | 2.043 | 1.00 | |
| 192_P | 204_N | 2.04 | 1.00 | |
| 141_L | 149_G | 1.984 | 1.00 | |
| 160_A | 176_L | 1.96 | 1.00 | |
| 6_T | 248_E | 1.861 | 1.00 | |
| 139_L | 175_F | 1.845 | 1.00 | |
| 153_E | 158_R | 1.819 | 1.00 | |
| 210_N | 215_S | 1.801 | 1.00 | |
| 219_I | 243_G | 1.775 | 1.00 | |
| 71_Q | 97_P | 1.765 | 1.00 | |
| 158_R | 181_P | 1.727 | 1.00 | |
| 40_C | 161_W | 1.724 | 1.00 | |
| 141_L | 147_T | 1.702 | 1.00 | |
| 185_V | 221_T | 1.701 | 1.00 | |
| 130_D | 135_Q | 1.693 | 1.00 | |
| 49_A | 70_Q | 1.687 | 1.00 | |
| 4_T | 250_G | 1.679 | 1.00 | |
| 241_E | 247_M | 1.653 | 1.00 | |
| 141_L | 162_L | 1.637 | 1.00 | |
| 154_T | 157_S | 1.622 | 1.00 | |
| 5_L | 159_V | 1.614 | 1.00 | |
| 177_R | 180_Q | 1.599 | 1.00 | |
| 147_T | 163_S | 1.572 | 1.00 | |
| 55_A | 74_L | 1.568 | 1.00 | |
| 97_P | 120_S | 1.566 | 1.00 | |
| 219_I | 249_I | 1.563 | 1.00 | |
| 43_V | 50_I | 1.56 | 1.00 | |
| 176_L | 181_P | 1.555 | 1.00 | |
| 166_A | 205_T | 1.514 | 1.00 | |
| 75_T | 150_Y | 1.488 | 1.00 | |
| 243_G | 247_M | 1.485 | 1.00 | |
| 244_F | 247_M | 1.484 | 1.00 | |
| 97_P | 118_D | 1.461 | 1.00 | |
| 162_L | 186_M | 1.445 | 1.00 | |
| 53_I | 150_Y | 1.443 | 1.00 | |
| 136_V | 152_L | 1.443 | 1.00 | |
| 81_H | 222_H | 1.441 | 1.00 | |
| 71_Q | 99_Y | 1.441 | 1.00 | |
| 219_I | 241_E | 1.422 | 1.00 | |
| 128_V | 137_T | 1.405 | 0.99 | |
| 124_E | 127_V | 1.401 | 0.99 | |
| 208_A | 211_Q | 1.387 | 0.99 | |
| 142_N | 166_A | 1.386 | 0.99 | |
| 151_L | 181_P | 1.379 | 0.99 | |
| 73_L | 150_Y | 1.376 | 0.99 | |
| 7_L | 42_G | 1.356 | 0.99 | |
| 166_A | 201_C | 1.35 | 0.99 | |
| 53_I | 73_L | 1.343 | 0.99 | |
| 205_T | 208_A | 1.341 | 0.99 | |
| 5_L | 44_V | 1.338 | 0.99 | |
| 51_T | 134_L | 1.337 | 0.99 | |
| 105_Q | 108_D | 1.33 | 0.99 | |
| 72_F | 85_L | 1.315 | 0.99 | |
| 51_T | 71_Q | 1.307 | 0.99 | |
| 215_S | 218_V | 1.295 | 0.99 | |
| 128_V | 135_Q | 1.281 | 0.99 | |
| 49_A | 132_Q | 1.281 | 0.99 | |
| 128_V | 138_P | 1.266 | 0.99 | |
| 188_C | 220_L | 1.246 | 0.98 | |
| 50_I | 70_Q | 1.225 | 0.98 | |
| 151_L | 160_A | 1.221 | 0.98 | |
| 97_P | 121_H | 1.215 | 0.98 | |
| 221_T | 243_G | 1.206 | 0.98 | |
| 149_G | 162_L | 1.206 | 0.98 | |
| 217_R | 239_G | 1.2 | 0.98 | |
| 188_C | 206_V | 1.197 | 0.98 | |
| 51_T | 136_V | 1.193 | 0.98 | |
| 176_L | 213_I | 1.188 | 0.98 | |
| 41_S | 60_L | 1.181 | 0.98 | |
| 74_L | 85_L | 1.168 | 0.97 | |
| 204_N | 208_A | 1.156 | 0.97 | |
| 79_M | 83_Q | 1.149 | 0.97 | |
| 10_T | 245_D | 1.141 | 0.97 | |
| 170_E | 212_V | 1.132 | 0.97 | |
| 177_R | 214_R | 1.122 | 0.97 | |
| 202_D | 205_T | 1.114 | 0.96 | |
| 7_L | 219_I | 1.113 | 0.96 | |
| 162_L | 184_M | 1.11 | 0.96 | |
| 102_P | 124_E | 1.097 | 0.96 | |
| 177_R | 212_V | 1.09 | 0.96 | |
| 73_L | 129_F | 1.089 | 0.96 | |
| 203_L | 207_L | 1.078 | 0.95 | |
| 42_G | 221_T | 1.077 | 0.95 | |
| 123_V | 150_Y | 1.072 | 0.95 | |
| 74_L | 104_E | 1.052 | 0.95 | |
| 143_H | 164_D | 1.047 | 0.94 | |
| 207_L | 240_F | 1.044 | 0.94 | |
| 181_P | 215_S | 1.036 | 0.94 | |
| 169_P | 173_L | 1.033 | 0.94 | |
| 42_G | 53_I | 1.032 | 0.94 | |
| 101_P | 148_F | 1.024 | 0.93 | |
| 206_V | 210_N | 1.023 | 0.93 | |
| 7_L | 185_V | 1.023 | 0.93 | |
| 189_S | 224_S | 1.017 | 0.93 | |
| 72_F | 88_L | 1.012 | 0.93 | |
| 138_P | 150_Y | 1.009 | 0.93 | |
| 180_Q | 216_P | 1.007 | 0.93 | |
| 230_W | 234_N | 1.005 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3g1pA | 2 | 0.996 | 100 | 0.212 | Contact Map | 0.856 |
| 3jxpA | 1 | 0.9762 | 100 | 0.257 | Contact Map | 0.701 |
| 3md7A | 1 | 0.9484 | 100 | 0.31 | Contact Map | 0.818 |
| 3zwfA | 2 | 0.9087 | 100 | 0.315 | Contact Map | 0.859 |
| 2cbnA | 1 | 0.9008 | 100 | 0.328 | Contact Map | 0.839 |
| 1y44A | 2 | 0.9008 | 100 | 0.338 | Contact Map | 0.868 |
| 1zkpA | 4 | 0.9008 | 100 | 0.38 | Contact Map | 0.867 |
| 2e7yA | 2 | 0.8532 | 100 | 0.45 | Contact Map | 0.683 |
| 3bk2A | 1 | 0.8889 | 100 | 0.525 | Contact Map | 0.573 |
| 3rpcA | 4 | 0.8452 | 100 | 0.527 | Contact Map | 0.763 |
Sequence Conservation (Image Generated using WebLogo v3)