May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org
KATG - Catalase-peroxidase
UniProt: P13029 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10511
Length: 726 (712)
Sequences: 816
Seq/Len: 1.15
KATG
Paralog alert: 0.12 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
438_L 557_V 4.715 1.00
443_Y 523_A 4.377 1.00
241_A 376_T 3.946 1.00
387_E 391_R 3.816 1.00
65_E 68_K 3.614 1.00
539_K 543_A 3.587 1.00
385_E 388_K 3.504 1.00
137_V 311_T 3.467 1.00
495_M 499_D 3.437 1.00
331_E 394_L 3.427 1.00
628_N 678_S 3.366 1.00
179_F 432_L 3.253 1.00
419_K 431_D 3.203 1.00
458_A 535_V 3.2 1.00
61_D 64_K 2.947 1.00
71_Y 74_L 2.894 1.00
81_L 149_I 2.88 1.00
65_E 156_K 2.849 1.00
74_L 157_I 2.776 1.00
47_N 689_V 2.768 1.00
396_D 399_A 2.744 1.00
78_L 82_L 2.709 1.00
75_K 426_E 2.539 1.00
124_Q 188_V 2.528 1.00
460_S 516_I 2.498 0.99
402_E 406_R 2.479 0.99
561_Q 566_I 2.477 0.99
330_F 390_S 2.464 0.99
457_I 532_A 2.454 0.99
466_E 508_R 2.407 0.99
553_A 725_L 2.296 0.99
93_W 317_V 2.268 0.99
71_Y 183_A 2.259 0.99
342_R 348_I 2.211 0.98
241_A 379_T 2.2 0.98
362_P 369_R 2.2 0.98
335_K 394_L 2.2 0.98
361_D 369_R 2.185 0.98
277_P 280_N 2.18 0.98
64_K 67_S 2.178 0.98
171_L 176_F 2.172 0.98
579_F 599_A 2.144 0.98
495_M 498_R 2.097 0.98
196_N 214_K 2.092 0.98
151_Q 700_S 2.092 0.98
458_A 536_G 2.077 0.97
651_Y 665_G 2.076 0.97
120_A 164_I 2.058 0.97
352_A 368_K 2.058 0.97
44_D 193_L 2.054 0.97
79_K 169_V 2.053 0.97
464_V 468_V 2.043 0.97
467_L 532_A 2.037 0.97
155_Q 699_S 2.029 0.97
603_T 720_L 2.016 0.97
292_E 298_A 2.013 0.97
321_T 328_Y 2.01 0.97
320_Q 332_N 2.009 0.97
331_E 335_K 2.008 0.97
352_A 370_K 1.981 0.96
211_A 244_A 1.98 0.96
634_R 703_H 1.961 0.96
534_V 715_V 1.959 0.96
260_V 390_S 1.956 0.96
317_V 362_P 1.942 0.96
504_A 624_D 1.935 0.96
339_V 353_V 1.911 0.95
80_A 84_E 1.911 0.95
95_S 174_S 1.906 0.95
378_L 382_F 1.894 0.95
257_E 392_R 1.887 0.95
113_S 571_L 1.885 0.95
95_S 173_N 1.884 0.95
78_L 81_L 1.878 0.95
107_G 164_I 1.851 0.94
82_L 100_F 1.843 0.94
104_A 107_G 1.837 0.94
307_A 363_F 1.835 0.94
620_G 636_G 1.833 0.94
97_A 174_S 1.829 0.94
578_G 595_L 1.822 0.93
164_I 412_T 1.818 0.93
474_S 490_A 1.814 0.93
309_A 363_F 1.812 0.93
664_E 673_V 1.807 0.93
666_R 673_V 1.803 0.93
93_W 316_V 1.781 0.92
480_G 603_T 1.776 0.92
68_K 156_K 1.775 0.92
263_I 376_T 1.773 0.92
321_T 326_S 1.754 0.92
616_M 621_A 1.754 0.92
352_A 359_I 1.752 0.91
320_Q 328_Y 1.751 0.91
169_V 426_E 1.748 0.91
332_N 336_Y 1.744 0.91
351_E 370_K 1.733 0.91
548_I 711_V 1.732 0.91
56_L 155_Q 1.722 0.91
205_T 233_D 1.718 0.90
542_S 547_S 1.711 0.90
139_L 142_A 1.709 0.90
592_E 679_R 1.7 0.90
66_F 423_I 1.699 0.90
359_I 371_P 1.698 0.90
406_R 432_L 1.697 0.90
66_F 183_A 1.687 0.89
699_S 702_A 1.675 0.89
276_G 299_S 1.673 0.89
611_A 702_A 1.672 0.89
289_P 292_E 1.665 0.88
121_G 253_G 1.663 0.88
179_F 406_R 1.635 0.87
440_Q 557_V 1.626 0.87
104_A 163_F 1.615 0.86
606_A 693_V 1.605 0.86
334_F 390_S 1.604 0.86
493_A 514_E 1.593 0.85
523_A 528_I 1.589 0.85
358_I 370_K 1.586 0.85
99_L 139_L 1.573 0.84
460_S 512_V 1.565 0.84
350_F 375_V 1.56 0.84
532_A 536_G 1.545 0.83
645_N 675_F 1.54 0.83
99_L 142_A 1.54 0.83
512_V 515_K 1.539 0.83
450_I 534_V 1.537 0.82
330_F 394_L 1.536 0.82
263_I 374_L 1.534 0.82
107_G 163_F 1.529 0.82
628_N 676_T 1.518 0.81
174_S 269_L 1.518 0.81
457_I 535_V 1.516 0.81
523_A 532_A 1.516 0.81
79_K 173_N 1.505 0.81
272_T 372_T 1.501 0.80
78_L 84_E 1.5 0.80
456_A 519_E 1.497 0.80
620_G 635_V 1.496 0.80
376_T 379_T 1.49 0.80
316_V 372_T 1.481 0.79
504_A 623_F 1.478 0.79
447_E 549_H 1.477 0.79
535_V 543_A 1.472 0.79
618_V 630_V 1.468 0.78
474_S 477_T 1.462 0.78
357_E 370_K 1.458 0.78
268_T 400_F 1.457 0.78
328_Y 332_N 1.457 0.78
272_T 374_L 1.455 0.77
340_Q 348_I 1.442 0.77
302_G 308_D 1.442 0.77
398_Q 401_N 1.437 0.76
72_Y 426_E 1.435 0.76
280_N 300_T 1.433 0.76
704_E 708_K 1.429 0.76
481_G 601_Q 1.422 0.75
299_S 309_A 1.421 0.75
163_F 412_T 1.418 0.75
78_L 149_I 1.414 0.75
444_N 449_D 1.407 0.74
715_V 719_N 1.399 0.73
66_F 71_Y 1.397 0.73
490_A 525_L 1.394 0.73
381_R 391_R 1.392 0.73
381_R 387_E 1.39 0.73
276_G 280_N 1.389 0.73
239_L 382_F 1.384 0.72
548_I 708_K 1.383 0.72
453_L 528_I 1.377 0.72
182_G 427_V 1.375 0.72
284_D 287_A 1.375 0.72
392_R 399_A 1.37 0.71
235_S 348_I 1.367 0.71
458_A 543_A 1.366 0.71
490_A 529_I 1.363 0.71
206_H 233_D 1.357 0.70
464_V 543_A 1.356 0.70
42_R 45_L 1.352 0.70
317_V 372_T 1.344 0.69
326_S 332_N 1.339 0.69
239_L 379_T 1.337 0.68
71_Y 425_P 1.333 0.68
449_D 452_D 1.326 0.68
546_L 703_H 1.326 0.68
83_T 173_N 1.325 0.67
409_F 422_Y 1.323 0.67
263_I 380_L 1.323 0.67
352_A 357_E 1.318 0.67
245_I 380_L 1.317 0.67
352_A 379_T 1.308 0.66
121_G 483_K 1.306 0.66
316_V 326_S 1.305 0.66
359_I 369_R 1.303 0.66
71_Y 426_E 1.299 0.65
260_V 264_A 1.295 0.65
543_A 636_G 1.295 0.65
583_R 591_T 1.294 0.65
208_H 211_A 1.291 0.65
463_S 466_E 1.29 0.64
317_V 374_L 1.28 0.64
98_G 363_F 1.277 0.63
65_E 155_Q 1.266 0.62
57_G 708_K 1.264 0.62
570_E 573_E 1.263 0.62
236_G 340_Q 1.258 0.62
280_N 299_S 1.253 0.61
212_L 233_D 1.249 0.61
314_L 374_L 1.242 0.60
155_Q 702_A 1.237 0.60
242_A 388_K 1.232 0.59
390_S 393_F 1.231 0.59
352_A 356_P 1.23 0.59
179_F 402_E 1.23 0.59
307_A 362_P 1.229 0.59
213_A 244_A 1.225 0.59
409_F 433_I 1.224 0.58
104_A 164_I 1.224 0.58
264_A 400_F 1.223 0.58
104_A 412_T 1.219 0.58
93_W 372_T 1.218 0.58
536_G 543_A 1.215 0.58
208_H 244_A 1.214 0.58
166_A 169_V 1.205 0.57
628_N 662_L 1.2 0.56
259_T 386_F 1.196 0.56
341_T 351_E 1.194 0.56
97_A 269_L 1.189 0.55
299_S 379_T 1.18 0.54
208_H 220_T 1.179 0.54
590_T 593_S 1.177 0.54
221_E 233_D 1.176 0.54
328_Y 331_E 1.173 0.54
303_S 307_A 1.172 0.54
542_S 674_K 1.172 0.54
52_R 605_T 1.171 0.53
591_T 661_E 1.166 0.53
469_S 621_A 1.163 0.53
264_A 330_F 1.163 0.53
69_L 74_L 1.161 0.52
559_A 563_Q 1.16 0.52
124_Q 195_V 1.159 0.52
316_V 374_L 1.151 0.51
359_I 370_K 1.151 0.51
583_R 594_L 1.148 0.51
467_L 535_V 1.143 0.51
465_S 621_A 1.143 0.51
218_G 419_K 1.142 0.51
330_F 393_F 1.142 0.51
512_V 516_I 1.142 0.51
54_N 186_E 1.141 0.51
303_S 306_G 1.14 0.50
525_L 529_I 1.14 0.50
355_A 370_K 1.138 0.50
584_A 587_D 1.137 0.50
95_S 269_L 1.136 0.50
239_L 242_A 1.134 0.50
513_L 532_A 1.13 0.49
517_Q 528_I 1.128 0.49
63_R 423_I 1.127 0.49
211_A 220_T 1.127 0.49
478_F 483_K 1.126 0.49
209_P 212_L 1.123 0.49
374_L 378_L 1.121 0.49
399_A 403_A 1.118 0.48
179_F 430_E 1.117 0.48
504_A 689_V 1.117 0.48
82_L 95_S 1.116 0.48
290_I 683_V 1.112 0.48
241_A 329_F 1.111 0.48
263_I 378_L 1.11 0.48
290_I 663_F 1.11 0.48
352_A 372_T 1.106 0.47
236_G 348_I 1.105 0.47
575_I 594_L 1.103 0.47
122_R 188_V 1.098 0.46
98_G 359_I 1.097 0.46
260_V 380_L 1.097 0.46
253_G 568_M 1.094 0.46
74_L 183_A 1.085 0.45
361_D 371_P 1.085 0.45
321_T 324_Q 1.084 0.45
543_A 637_V 1.082 0.45
74_L 165_L 1.081 0.45
247_A 386_F 1.077 0.44
440_Q 443_Y 1.077 0.44
104_A 438_L 1.073 0.44
444_N 447_E 1.072 0.44
171_L 404_F 1.072 0.44
107_G 412_T 1.07 0.44
550_V 711_V 1.07 0.44
293_Q 631_F 1.067 0.43
45_L 193_L 1.067 0.43
280_N 301_Y 1.062 0.43
444_N 520_S 1.061 0.43
43_V 596_I 1.061 0.43
657_D 661_E 1.06 0.43
306_G 363_F 1.06 0.43
128_A 286_E 1.06 0.43
329_F 380_L 1.053 0.42
269_L 401_N 1.053 0.42
334_F 387_E 1.052 0.42
391_R 395_N 1.051 0.42
32_T 694_A 1.05 0.42
87_P 669_E 1.049 0.42
517_Q 523_A 1.047 0.42
61_D 67_S 1.044 0.41
205_T 211_A 1.041 0.41
245_I 263_I 1.039 0.41
441_P 521_G 1.039 0.41
40_Q 689_V 1.038 0.41
124_Q 192_D 1.036 0.41
188_V 192_D 1.03 0.40
50_S 605_T 1.03 0.40
288_A 292_E 1.027 0.40
264_A 390_S 1.023 0.39
207_R 211_A 1.017 0.39
260_V 334_F 1.016 0.39
283_P 287_A 1.011 0.38
307_A 364_D 1.01 0.38
532_A 644_V 1.006 0.38
631_F 675_F 1.006 0.38
498_R 507_V 1.005 0.38
579_F 595_L 1.005 0.38
122_R 192_D 1.005 0.38
657_D 663_F 1.002 0.37
263_I 314_L 1.001 0.37
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3ut2A20.97661000.369Contact Map0.66
3vliA20.96011000.385Contact Map0.679
1ub2A10.94211000.385Contact Map0.594
3n3rA20.95591000.389Contact Map0.676
2ccaA20.96141000.401Contact Map0.687
1u2kA10.39811000.78Contact Map0.615
3e2oA10.39671000.858Contact Map0.572
1iynA10.36641000.871Contact Map0.59
3m5qA10.47931000.872Contact Map0.409
1llpA10.45451000.873Contact Map0.4
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
Page generated in 0.0538 seconds.