| UniProt: | P12996 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10118 | ||
| Length: | 346 (313) | ||
| Sequences: | 2956 | ||
| Seq/Len: | 9.44 |
| BIOB
Paralog alert: 0.58 [within 20: 0.14] - ratio of genomes with paralogs Cluster includes: BIOB THIH |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 114_E | 141_R | 4.243 | 1.00 | |
| 158_P | 171_Q | 4.017 | 1.00 | |
| 136_E | 182_D | 3.826 | 1.00 | |
| 121_K | 148_D | 3.369 | 1.00 | |
| 30_V | 252_I | 3.3 | 1.00 | |
| 159_E | 201_D | 3.015 | 1.00 | |
| 78_V | 115_Q | 2.939 | 1.00 | |
| 77_E | 80_Q | 2.885 | 1.00 | |
| 9_L | 204_G | 2.829 | 1.00 | |
| 110_M | 114_E | 2.775 | 1.00 | |
| 28_Q | 32_R | 2.561 | 1.00 | |
| 219_V | 254_M | 2.528 | 1.00 | |
| 207_L | 253_M | 2.528 | 1.00 | |
| 178_E | 217_E | 2.52 | 1.00 | |
| 171_Q | 175_D | 2.511 | 1.00 | |
| 136_E | 179_K | 2.43 | 1.00 | |
| 111_P | 141_R | 2.338 | 1.00 | |
| 81_V | 116_M | 2.296 | 1.00 | |
| 78_V | 119_G | 2.261 | 1.00 | |
| 136_E | 140_Q | 2.212 | 1.00 | |
| 83_E | 86_R | 2.208 | 1.00 | |
| 157_S | 201_D | 2.167 | 1.00 | |
| 115_Q | 118_Q | 2.137 | 1.00 | |
| 82_L | 119_G | 2.095 | 1.00 | |
| 159_E | 204_G | 2.077 | 1.00 | |
| 199_V | 242_D | 2.058 | 1.00 | |
| 15_L | 249_V | 2.038 | 1.00 | |
| 13_T | 200_K | 2.029 | 1.00 | |
| 291_L | 294_P | 1.887 | 1.00 | |
| 26_E | 252_I | 1.861 | 1.00 | |
| 258_Y | 282_N | 1.84 | 1.00 | |
| 202_R | 242_D | 1.838 | 1.00 | |
| 140_Q | 144_N | 1.831 | 1.00 | |
| 9_L | 207_L | 1.829 | 1.00 | |
| 154_L | 205_L | 1.792 | 1.00 | |
| 119_G | 122_A | 1.775 | 1.00 | |
| 7_W | 252_I | 1.773 | 1.00 | |
| 88_A | 93_S | 1.752 | 1.00 | |
| 28_Q | 278_M | 1.716 | 1.00 | |
| 189_S | 209_L | 1.711 | 1.00 | |
| 259_V | 281_A | 1.695 | 1.00 | |
| 303_Q | 307_K | 1.672 | 1.00 | |
| 56_D | 66_Y | 1.671 | 1.00 | |
| 13_T | 17_E | 1.655 | 1.00 | |
| 32_R | 38_R | 1.637 | 1.00 | |
| 80_Q | 83_E | 1.634 | 1.00 | |
| 114_E | 118_Q | 1.626 | 1.00 | |
| 86_R | 90_A | 1.618 | 1.00 | |
| 175_D | 179_K | 1.613 | 1.00 | |
| 206_L | 250_A | 1.584 | 1.00 | |
| 149_Y | 186_K | 1.558 | 1.00 | |
| 143_A | 185_I | 1.537 | 1.00 | |
| 13_T | 203_A | 1.524 | 1.00 | |
| 16_F | 249_V | 1.506 | 1.00 | |
| 87_K | 90_A | 1.505 | 1.00 | |
| 141_R | 144_N | 1.503 | 1.00 | |
| 86_R | 123_M | 1.476 | 1.00 | |
| 85_A | 120_V | 1.475 | 1.00 | |
| 82_L | 86_R | 1.468 | 1.00 | |
| 288_C | 294_P | 1.458 | 1.00 | |
| 12_V | 253_M | 1.452 | 1.00 | |
| 270_E | 307_K | 1.444 | 1.00 | |
| 302_L | 306_R | 1.442 | 1.00 | |
| 140_Q | 143_A | 1.44 | 1.00 | |
| 306_R | 312_P | 1.437 | 1.00 | |
| 159_E | 163_N | 1.428 | 0.99 | |
| 117_V | 147_L | 1.427 | 0.99 | |
| 137_S | 140_Q | 1.42 | 0.99 | |
| 261_L | 276_C | 1.418 | 0.99 | |
| 143_A | 183_A | 1.416 | 0.99 | |
| 9_L | 200_K | 1.414 | 0.99 | |
| 9_L | 203_A | 1.367 | 0.99 | |
| 172_E | 175_D | 1.363 | 0.99 | |
| 240_A | 272_T | 1.362 | 0.99 | |
| 83_E | 87_K | 1.357 | 0.99 | |
| 18_K | 26_E | 1.357 | 0.99 | |
| 118_Q | 145_A | 1.342 | 0.99 | |
| 24_L | 279_A | 1.34 | 0.99 | |
| 207_L | 211_N | 1.333 | 0.99 | |
| 244_I | 276_C | 1.324 | 0.99 | |
| 12_V | 207_L | 1.317 | 0.99 | |
| 8_T | 11_Q | 1.312 | 0.99 | |
| 12_V | 203_A | 1.291 | 0.99 | |
| 159_E | 198_T | 1.283 | 0.99 | |
| 139_A | 183_A | 1.268 | 0.99 | |
| 7_W | 12_V | 1.267 | 0.99 | |
| 178_E | 182_D | 1.264 | 0.98 | |
| 23_L | 245_R | 1.262 | 0.98 | |
| 198_T | 201_D | 1.253 | 0.98 | |
| 39_Q | 311_N | 1.251 | 0.98 | |
| 9_L | 13_T | 1.25 | 0.98 | |
| 152_H | 173_R | 1.248 | 0.98 | |
| 193_V | 246_T | 1.24 | 0.98 | |
| 204_G | 207_L | 1.239 | 0.98 | |
| 117_V | 127_A | 1.239 | 0.98 | |
| 160_F | 163_N | 1.236 | 0.98 | |
| 47_S | 50_T | 1.234 | 0.98 | |
| 111_P | 115_Q | 1.229 | 0.98 | |
| 114_E | 145_A | 1.228 | 0.98 | |
| 179_K | 182_D | 1.228 | 0.98 | |
| 169_T | 172_E | 1.221 | 0.98 | |
| 202_R | 246_T | 1.219 | 0.98 | |
| 193_V | 243_F | 1.209 | 0.98 | |
| 239_D | 242_D | 1.208 | 0.98 | |
| 118_Q | 144_N | 1.206 | 0.98 | |
| 17_E | 199_V | 1.202 | 0.98 | |
| 50_T | 101_A | 1.202 | 0.98 | |
| 29_Q | 33_Q | 1.201 | 0.98 | |
| 74_R | 104_N | 1.196 | 0.98 | |
| 113_L | 131_L | 1.185 | 0.97 | |
| 28_Q | 31_H | 1.182 | 0.97 | |
| 136_E | 183_A | 1.175 | 0.97 | |
| 6_R | 215_P | 1.172 | 0.97 | |
| 94_T | 314_Q | 1.165 | 0.97 | |
| 303_Q | 306_R | 1.158 | 0.97 | |
| 170_Y | 174_L | 1.155 | 0.97 | |
| 206_L | 209_L | 1.154 | 0.97 | |
| 16_F | 246_T | 1.153 | 0.97 | |
| 25_F | 29_Q | 1.149 | 0.97 | |
| 158_P | 162_G | 1.148 | 0.97 | |
| 134_L | 142_L | 1.143 | 0.97 | |
| 299_D | 303_Q | 1.136 | 0.96 | |
| 206_L | 253_M | 1.136 | 0.96 | |
| 226_K | 237_D | 1.135 | 0.96 | |
| 113_L | 142_L | 1.133 | 0.96 | |
| 76_M | 81_V | 1.133 | 0.96 | |
| 19_P | 22_D | 1.133 | 0.96 | |
| 135_S | 138_Q | 1.131 | 0.96 | |
| 21_L | 24_L | 1.125 | 0.96 | |
| 300_K | 303_Q | 1.124 | 0.96 | |
| 42_V | 302_L | 1.1 | 0.96 | |
| 82_L | 123_M | 1.1 | 0.96 | |
| 6_R | 216_P | 1.099 | 0.96 | |
| 107_E | 141_R | 1.097 | 0.95 | |
| 297_E | 300_K | 1.09 | 0.95 | |
| 6_R | 255_P | 1.083 | 0.95 | |
| 158_P | 208_Q | 1.079 | 0.95 | |
| 58_K | 164_I | 1.076 | 0.95 | |
| 12_V | 249_V | 1.07 | 0.95 | |
| 247_I | 276_C | 1.052 | 0.94 | |
| 47_S | 73_E | 1.049 | 0.94 | |
| 44_T | 93_S | 1.047 | 0.94 | |
| 178_E | 212_L | 1.036 | 0.93 | |
| 203_A | 249_V | 1.026 | 0.93 | |
| 52_A | 72_A | 1.02 | 0.93 | |
| 262_S | 265_R | 1.015 | 0.92 | |
| 14_E | 17_E | 1.009 | 0.92 | |
| 140_Q | 183_A | 1.007 | 0.92 | |
| 84_S | 87_K | 1.002 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1r30A | 2 | 0.9971 | 100 | 0.421 | Contact Map | 0.7 |
| 3t7vA | 1 | 0.9075 | 100 | 0.504 | Contact Map | 0.64 |
| 3iixA | 1 | 0.9162 | 100 | 0.52 | Contact Map | 0.746 |
| 1oltA | 1 | 0.9595 | 99.8 | 0.803 | Contact Map | 0.472 |
| 2qgqA | 8 | 0.8006 | 99.7 | 0.82 | Contact Map | 0.687 |
| 4jc0A | 2 | 0.922 | 99.7 | 0.822 | Contact Map | 0.603 |
| 1tv8A | 2 | 0.8497 | 99.7 | 0.826 | Contact Map | 0.641 |
| 3rfaA | 2 | 0.8266 | 99.6 | 0.838 | Contact Map | 0.444 |
| 3c8fA | 1 | 0.6474 | 99.6 | 0.843 | Contact Map | 0.539 |
| 2yx0A | 1 | 0.8092 | 99.5 | 0.846 | Contact Map | 0.525 |
Sequence Conservation (Image Generated using WebLogo v3)