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OPENSEQ.org
YIBD - Uncharacterized glycosyltransferase YibD
UniProt: P11290 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11266
Length: 344 (326)
Sequences: 395
Seq/Len: 1.21
YIBD
Paralog alert: 0.09 [within 20: 0.02] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
68_Q 71_A 3.443 1.00
16_N 46_T 3.357 1.00
73_A 166_V 3.356 1.00
73_A 222_V 3.156 1.00
26_E 56_Y 3.05 1.00
23_T 216_Y 2.978 1.00
54_K 67_H 2.827 1.00
173_R 177_V 2.817 1.00
68_Q 75_V 2.766 1.00
12_I 28_L 2.738 1.00
90_A 103_Y 2.686 1.00
50_V 67_H 2.654 1.00
81_I 89_V 2.583 1.00
66_L 79_R 2.527 1.00
40_I 53_A 2.405 0.99
71_A 75_V 2.371 0.99
46_T 49_S 2.363 0.99
14_L 49_S 2.361 0.99
42_N 67_H 2.341 0.99
28_L 98_V 2.325 0.99
115_L 206_R 2.256 0.99
82_E 182_K 2.215 0.99
25_M 40_I 2.198 0.99
79_R 83_V 2.152 0.98
32_T 104_E 2.139 0.98
50_V 54_K 2.104 0.98
75_V 185_A 2.05 0.97
102_M 120_C 2.023 0.97
90_A 102_M 1.987 0.97
25_M 63_V 1.863 0.95
17_A 94_A 1.86 0.95
66_L 83_V 1.852 0.95
50_V 65_L 1.835 0.94
50_V 53_A 1.81 0.94
175_V 198_F 1.784 0.93
9_S 37_E 1.736 0.92
24_C 92_V 1.719 0.91
102_M 106_L 1.714 0.91
41_I 76_A 1.712 0.91
92_V 213_Y 1.711 0.91
53_A 67_H 1.701 0.91
186_G 222_V 1.601 0.87
8_L 32_T 1.565 0.85
16_N 49_S 1.549 0.84
320_S 323_L 1.541 0.84
33_W 36_L 1.537 0.84
7_K 85_T 1.516 0.82
107_M 111_L 1.512 0.82
52_I 56_Y 1.508 0.82
39_I 66_L 1.495 0.81
218_H 221_S 1.481 0.80
148_T 151_D 1.465 0.79
54_K 65_L 1.459 0.79
115_L 204_R 1.452 0.79
64_R 85_T 1.426 0.77
21_F 40_I 1.384 0.74
18_G 46_T 1.381 0.73
8_L 103_Y 1.371 0.73
33_W 107_M 1.368 0.72
8_L 118_A 1.358 0.72
73_A 94_A 1.355 0.71
14_L 53_A 1.354 0.71
18_G 48_N 1.352 0.71
22_R 55_Y 1.344 0.71
22_R 26_E 1.343 0.70
11_I 80_G 1.338 0.70
105_T 210_Q 1.326 0.69
117_V 198_F 1.322 0.69
166_V 222_V 1.319 0.68
17_A 73_A 1.319 0.68
71_A 76_A 1.309 0.68
176_I 194_W 1.304 0.67
8_L 170_V 1.286 0.66
116_D 172_R 1.273 0.64
106_L 118_A 1.27 0.64
68_Q 73_A 1.266 0.64
117_V 199_M 1.259 0.63
194_W 198_F 1.239 0.61
36_L 103_Y 1.239 0.61
14_L 21_F 1.23 0.61
41_I 73_A 1.222 0.60
189_H 222_V 1.219 0.60
15_Y 174_D 1.218 0.59
87_K 111_L 1.216 0.59
85_T 127_R 1.216 0.59
8_L 107_M 1.212 0.59
25_M 56_Y 1.205 0.58
313_G 317_L 1.201 0.58
104_E 174_D 1.194 0.57
55_Y 58_E 1.191 0.57
12_I 94_A 1.188 0.57
68_Q 79_R 1.183 0.56
218_H 223_S 1.18 0.56
8_L 110_A 1.174 0.55
171_Y 198_F 1.153 0.53
39_I 71_A 1.144 0.52
317_L 324_W 1.144 0.52
38_I 63_V 1.135 0.51
184_I 193_V 1.131 0.51
40_I 54_K 1.13 0.51
106_L 120_C 1.127 0.51
17_A 20_D 1.125 0.50
38_I 53_A 1.12 0.50
117_V 173_R 1.114 0.49
92_V 106_L 1.114 0.49
29_I 38_I 1.108 0.49
55_Y 59_N 1.107 0.49
25_M 29_I 1.1 0.48
69_A 87_K 1.095 0.48
105_T 212_L 1.094 0.47
81_I 182_K 1.086 0.47
110_A 118_A 1.082 0.46
99_Y 214_K 1.08 0.46
85_T 110_A 1.079 0.46
166_V 169_G 1.075 0.46
42_N 48_N 1.069 0.45
29_I 56_Y 1.066 0.45
42_N 54_K 1.065 0.45
14_L 20_D 1.06 0.44
117_V 205_A 1.06 0.44
53_A 65_L 1.06 0.44
176_I 198_F 1.057 0.44
106_L 213_Y 1.057 0.44
8_L 60_Y 1.054 0.44
183_F 213_Y 1.052 0.43
41_I 189_H 1.039 0.42
14_L 40_I 1.032 0.41
25_M 167_W 1.032 0.41
122_A 167_W 1.028 0.41
7_K 42_N 1.026 0.41
37_E 84_A 1.022 0.41
319_W 324_W 1.021 0.40
91_F 183_F 1.02 0.40
12_I 24_C 1.02 0.40
14_L 52_I 1.02 0.40
40_I 50_V 1.018 0.40
41_I 220_T 1.006 0.39
42_N 127_R 1.005 0.39
56_Y 223_S 1.005 0.39
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3bcvA20.65991000.513Contact Map0.679
3l7iA40.9361000.543Contact Map0.568
1qg8A10.69191000.592Contact Map0.594
2z86A40.73841000.617Contact Map0.597
2d7iA10.91861000.658Contact Map0.518
4fixA20.95931000.678Contact Map0.487
1xhbA10.91571000.679Contact Map0.514
1fo8A10.85471000.681Contact Map0.511
3ckjA10.79651000.685Contact Map0.394
2ffuA10.94191000.688Contact Map0.524
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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