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OPENSEQ.org

YICG - UPF0126 inner membrane protein YicG
UniProt: P0AGM2 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11683
Length: 205 (202)
Sequences: 1175
Seq/Len: 5.82

YICG
Paralog alert: 0.44 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: YADS YICG
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
101_S 153_S 3.201 1.00
53_H 107_V 2.84 1.00
25_R 139_R 2.835 1.00
36_A 72_A 2.575 1.00
35_I 137_C 2.49 1.00
12_T 71_A 2.302 1.00
156_S 181_G 2.266 1.00
182_F 186_L 2.253 1.00
45_S 58_W 2.201 1.00
98_V 182_F 2.058 1.00
109_L 118_A 2.038 1.00
187_L 191_L 2.021 1.00
95_L 182_F 2.001 1.00
91_V 186_L 1.855 1.00
14_E 96_G 1.851 1.00
97_L 126_G 1.836 1.00
38_A 136_F 1.757 1.00
90_L 189_L 1.738 1.00
30_F 150_A 1.726 1.00
45_S 128_F 1.72 1.00
105_A 157_A 1.68 1.00
139_R 145_Q 1.664 1.00
11_I 14_E 1.632 1.00
27_M 137_C 1.624 0.99
7_Y 64_Y 1.612 0.99
159_L 180_F 1.592 0.99
53_H 111_M 1.575 0.99
123_V 154_F 1.486 0.99
187_L 193_L 1.475 0.99
36_A 68_V 1.456 0.99
102_I 181_G 1.428 0.98
10_G 14_E 1.428 0.98
188_A 193_L 1.424 0.98
21_A 137_C 1.422 0.98
71_A 75_T 1.408 0.98
33_I 72_A 1.405 0.98
35_I 138_K 1.401 0.98
101_S 105_A 1.399 0.98
108_A 121_A 1.392 0.98
40_A 68_V 1.391 0.98
97_L 153_S 1.384 0.98
105_A 161_I 1.383 0.98
94_A 182_F 1.373 0.98
98_V 102_I 1.363 0.98
58_W 128_F 1.353 0.98
4_H 8_L 1.353 0.98
45_S 57_G 1.34 0.97
131_V 136_F 1.331 0.97
136_F 144_F 1.307 0.97
155_A 184_A 1.302 0.97
105_A 122_A 1.296 0.97
162_A 166_Y 1.296 0.97
148_L 152_V 1.293 0.96
11_I 41_I 1.289 0.96
179_V 183_F 1.272 0.96
45_S 56_L 1.263 0.96
98_V 178_L 1.242 0.95
62_P 66_I 1.24 0.95
119_V 158_V 1.221 0.95
58_W 117_I 1.217 0.95
118_A 122_A 1.212 0.94
118_A 161_I 1.2 0.94
34_I 150_A 1.197 0.94
119_V 154_F 1.19 0.94
37_T 68_V 1.19 0.94
51_L 113_H 1.168 0.93
96_G 100_F 1.165 0.93
14_E 17_T 1.164 0.93
16_M 75_T 1.161 0.93
113_H 117_I 1.155 0.92
141_P 144_F 1.145 0.92
46_V 132_L 1.142 0.92
99_V 103_I 1.137 0.92
41_I 68_V 1.133 0.91
173_V 177_T 1.13 0.91
143_V 183_F 1.126 0.91
37_T 65_V 1.109 0.90
50_L 59_V 1.098 0.90
98_V 156_S 1.096 0.89
122_A 177_T 1.09 0.89
13_A 96_G 1.087 0.89
45_S 50_L 1.085 0.89
105_A 118_A 1.074 0.88
100_F 185_R 1.065 0.88
56_L 59_V 1.065 0.88
152_V 184_A 1.065 0.88
46_V 124_T 1.062 0.87
11_I 15_A 1.056 0.87
162_A 165_H 1.055 0.87
23_G 32_V 1.051 0.87
165_H 179_V 1.046 0.86
180_F 183_F 1.045 0.86
162_A 179_V 1.036 0.86
103_I 125_T 1.035 0.86
178_L 182_F 1.029 0.85
6_L 99_V 1.026 0.85
108_A 113_H 1.024 0.85
30_F 34_I 1.019 0.84
57_G 121_A 1.005 0.83
160_Y 177_T 1.005 0.83
25_R 46_V 1.002 0.83
100_F 144_F 1.001 0.83
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
2f2bA10.41465.20.964Contact Map0.42
3llqA20.40492.60.969Contact Map0.496
1s4zC10.14151.80.972Contact Map0
4bwzA10.92681.50.973Contact Map0.304
2o9gA10.40981.50.973Contact Map0.43
3gd8A10.40981.40.973Contact Map0.435
4i0uA100.395110.976Contact Map0.145
1vfgA20.42440.90.976Contact Map0.164
4b19A10.14630.90.976Contact Map0.021
2l2dA10.32680.80.977Contact Map0.109

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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