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OPENSEQ.org

PITA - Low-affinity inorganic phosphate transporter 1
UniProt: P0AFJ7 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12230
Length: 499 (483)
Sequences: 505
Seq/Len: 1.05

PITA
Paralog alert: 0.33 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: PITA PITB
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
55_V 59_V 3.617 1.00
191_H 197_R 2.241 0.98
444_V 449_V 1.897 0.94
152_V 430_A 1.809 0.92
165_V 181_W 1.78 0.91
95_A 131_I 1.774 0.91
350_T 356_K 1.657 0.86
350_T 353_K 1.654 0.86
118_A 484_A 1.643 0.86
66_L 388_M 1.628 0.85
231_Q 235_G 1.605 0.84
349_D 353_K 1.592 0.83
145_D 488_S 1.592 0.83
59_V 354_V 1.582 0.83
103_A 487_L 1.567 0.82
151_K 154_S 1.565 0.82
427_Q 430_A 1.563 0.82
349_D 356_K 1.536 0.80
19_A 47_A 1.516 0.79
25_F 109_L 1.481 0.77
353_K 356_K 1.481 0.77
160_I 164_I 1.48 0.77
100_M 124_L 1.475 0.76
108_N 120_S 1.439 0.74
17_L 21_A 1.438 0.74
151_K 242_I 1.431 0.73
63_L 67_L 1.424 0.73
141_T 338_S 1.402 0.71
83_D 245_A 1.398 0.71
167_L 459_V 1.382 0.69
208_F 212_I 1.37 0.68
109_L 183_G 1.367 0.68
18_L 478_V 1.353 0.67
48_M 406_A 1.352 0.67
350_T 358_P 1.351 0.67
11_H 183_G 1.334 0.66
412_K 448_H 1.332 0.65
309_S 312_I 1.331 0.65
353_K 358_P 1.326 0.65
15_L 97_V 1.313 0.64
162_S 383_P 1.311 0.64
66_L 384_V 1.307 0.63
417_G 427_Q 1.303 0.63
122_H 126_G 1.302 0.63
137_L 365_Q 1.287 0.61
120_S 123_T 1.28 0.61
30_N 120_S 1.276 0.60
243_G 430_A 1.274 0.60
426_A 450_L 1.273 0.60
24_L 393_A 1.271 0.60
2_L 312_I 1.271 0.60
147_L 418_M 1.265 0.59
18_L 102_L 1.264 0.59
41_T 450_L 1.256 0.59
41_T 426_A 1.25 0.58
442_M 453_S 1.246 0.58
313_N 335_D 1.245 0.58
235_G 238_M 1.24 0.57
48_M 268_N 1.239 0.57
15_L 18_L 1.239 0.57
394_L 398_T 1.238 0.57
430_A 484_A 1.237 0.57
246_P 397_G 1.233 0.57
94_L 235_G 1.232 0.56
59_V 490_G 1.232 0.56
179_R 245_A 1.225 0.56
153_L 157_G 1.224 0.56
25_F 406_A 1.223 0.56
176_L 209_W 1.221 0.55
72_V 447_T 1.214 0.55
312_I 315_L 1.21 0.54
219_I 354_V 1.208 0.54
174_I 466_Q 1.205 0.54
241_L 379_I 1.205 0.54
446_T 470_V 1.204 0.54
228_N 231_Q 1.204 0.54
412_K 429_T 1.199 0.53
74_Y 78_H 1.196 0.53
249_F 252_N 1.194 0.53
141_T 334_L 1.192 0.53
43_I 239_L 1.189 0.52
140_G 315_L 1.182 0.52
218_A 374_D 1.18 0.52
128_I 432_V 1.178 0.51
471_T 478_V 1.178 0.51
87_N 381_Y 1.175 0.51
93_G 404_R 1.173 0.51
230_G 404_R 1.17 0.51
80_L 84_L 1.169 0.51
129_I 136_A 1.165 0.50
413_I 473_I 1.164 0.50
411_E 427_Q 1.163 0.50
334_L 364_D 1.163 0.50
230_G 236_L 1.161 0.50
58_A 166_G 1.16 0.50
78_H 145_D 1.16 0.50
312_I 362_A 1.156 0.49
110_G 241_L 1.156 0.49
173_L 383_P 1.154 0.49
80_L 146_A 1.152 0.49
348_S 356_K 1.152 0.49
350_T 357_M 1.152 0.49
386_I 391_A 1.151 0.49
103_A 462_G 1.145 0.48
58_A 79_M 1.144 0.48
217_S 382_A 1.138 0.48
94_L 99_S 1.137 0.48
115_G 152_V 1.137 0.48
290_L 301_P 1.137 0.48
350_T 355_V 1.134 0.47
50_S 406_A 1.132 0.47
218_A 276_Q 1.132 0.47
162_S 448_H 1.131 0.47
437_A 481_L 1.131 0.47
14_L 168_V 1.131 0.47
40_A 442_M 1.131 0.47
233_G 236_L 1.13 0.47
349_D 357_M 1.126 0.46
182_S 267_I 1.123 0.46
169_F 429_T 1.122 0.46
125_I 155_I 1.12 0.46
178_R 461_D 1.119 0.46
362_A 365_Q 1.118 0.46
348_S 351_I 1.118 0.46
315_L 365_Q 1.118 0.46
453_S 484_A 1.116 0.46
137_L 478_V 1.116 0.46
413_I 482_P 1.114 0.45
83_D 87_N 1.114 0.45
82_T 386_I 1.114 0.45
16_L 412_K 1.113 0.45
117_P 447_T 1.113 0.45
18_L 28_A 1.11 0.45
103_A 470_V 1.108 0.45
135_N 491_L 1.108 0.45
222_A 235_G 1.106 0.45
178_R 466_Q 1.106 0.45
113_Y 478_V 1.105 0.45
310_N 340_M 1.104 0.44
59_V 486_L 1.102 0.44
179_R 490_G 1.099 0.44
235_G 242_I 1.098 0.44
348_S 372_K 1.097 0.44
28_A 399_M 1.096 0.44
183_G 406_A 1.096 0.44
47_A 160_I 1.095 0.44
316_N 336_Q 1.092 0.43
186_K 316_N 1.091 0.43
154_S 157_G 1.091 0.43
22_F 104_A 1.09 0.43
214_L 243_G 1.088 0.43
197_R 404_R 1.086 0.43
472_S 483_A 1.086 0.43
232_K 236_L 1.085 0.43
157_G 161_V 1.084 0.43
323_T 396_I 1.083 0.42
354_V 362_A 1.079 0.42
183_G 197_R 1.076 0.42
157_G 383_P 1.075 0.42
141_T 188_A 1.074 0.42
138_M 141_T 1.073 0.42
188_A 311_T 1.073 0.42
435_G 488_S 1.073 0.42
118_A 137_L 1.072 0.41
141_T 365_Q 1.072 0.41
198_E 201_D 1.072 0.41
336_Q 365_Q 1.068 0.41
471_T 475_M 1.068 0.41
260_I 332_L 1.068 0.41
138_M 335_D 1.066 0.41
324_T 335_D 1.065 0.41
106_I 109_L 1.065 0.41
84_L 240_V 1.064 0.41
85_L 427_Q 1.063 0.41
80_L 440_T 1.061 0.40
243_G 389_A 1.059 0.40
334_L 338_S 1.058 0.40
11_H 45_T 1.058 0.40
118_A 123_T 1.056 0.40
24_L 95_A 1.056 0.40
315_L 331_K 1.053 0.40
312_I 331_K 1.053 0.40
38_A 481_L 1.053 0.40
46_R 246_P 1.052 0.40
155_I 161_V 1.051 0.40
133_L 144_V 1.05 0.39
232_K 235_G 1.05 0.39
149_I 442_M 1.05 0.39
141_T 335_D 1.05 0.39
28_A 398_T 1.049 0.39
335_D 365_Q 1.049 0.39
395_G 465_L 1.048 0.39
213_A 430_A 1.045 0.39
74_Y 77_V 1.045 0.39
312_I 364_D 1.044 0.39
438_S 441_G 1.043 0.39
166_G 474_L 1.043 0.39
21_A 259_E 1.042 0.39
83_D 251_V 1.042 0.39
20_L 66_L 1.042 0.39
309_S 338_S 1.042 0.39
141_T 336_Q 1.041 0.39
312_I 365_Q 1.041 0.39
395_G 401_G 1.04 0.39
114_F 164_I 1.04 0.39
349_D 358_P 1.04 0.39
286_G 295_E 1.038 0.38
430_A 457_T 1.038 0.38
315_L 338_S 1.037 0.38
383_P 388_M 1.037 0.38
125_I 430_A 1.037 0.38
304_F 417_G 1.036 0.38
22_F 470_V 1.036 0.38
233_G 241_L 1.036 0.38
172_G 265_D 1.035 0.38
125_I 429_T 1.034 0.38
196_E 208_F 1.033 0.38
155_I 412_K 1.033 0.38
99_S 134_T 1.03 0.38
403_R 409_I 1.029 0.38
261_T 309_S 1.026 0.37
222_A 383_P 1.026 0.37
99_S 103_A 1.022 0.37
335_D 338_S 1.021 0.37
85_L 448_H 1.021 0.37
232_K 382_A 1.02 0.37
231_Q 381_Y 1.02 0.37
42_V 423_G 1.019 0.37
42_V 420_Y 1.019 0.37
241_L 381_Y 1.018 0.37
131_I 167_L 1.017 0.37
446_T 482_P 1.017 0.37
386_I 453_S 1.013 0.36
293_A 338_S 1.013 0.36
348_S 353_K 1.012 0.36
123_T 134_T 1.012 0.36
155_I 164_I 1.012 0.36
353_K 357_M 1.011 0.36
164_I 453_S 1.01 0.36
84_L 229_D 1.009 0.36
203_K 245_A 1.009 0.36
141_T 309_S 1.008 0.36
261_T 338_S 1.007 0.36
331_K 338_S 1.006 0.36
165_V 172_G 1.006 0.36
39_V 48_M 1.006 0.36
28_A 77_V 1.006 0.36
232_K 237_V 1.004 0.35
444_V 482_P 1.004 0.35
140_G 348_S 1.004 0.35
312_I 338_S 1.001 0.35
48_M 478_V 1.001 0.35
28_A 135_N 1.001 0.35
107_W 125_I 1 0.35
12_T 141_T 1 0.35
189_R 335_D 1 0.35
128_I 151_K 1 0.35
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
2jlnA10.3567130.983Contact Map0.097
2wwbA10.18848.80.984Contact Map0.025
3d9sA40.40686.20.986Contact Map0.154
2wscI10.08024.40.986Contact Map0.045
3c02A10.38484.20.987Contact Map0.056
2kluA10.070140.987Contact Map0
3lw5I10.06013.80.987Contact Map0.094
2jwaA20.08023.70.987Contact Map0.103
3s90C20.05813.60.987Contact Map0
1ldfA10.39883.30.987Contact Map0.127

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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