May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org
MOTB - Motility protein B
UniProt: P0AF06 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10602
Length: 308 (277)
Sequences: 681
Seq/Len: 2.46
MOTB
Paralog alert: 0.24 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
162_R 169_E 3.232 1.00
208_Y 216_D 2.877 1.00
212_E 223_R 2.855 1.00
40_F 44_M 2.711 1.00
197_D 210_N 2.649 1.00
29_A 33_F 2.375 1.00
29_A 38_M 2.285 1.00
51_S 54_E 2.222 1.00
40_F 43_V 2.099 1.00
119_R 123_D 2.035 0.99
248_S 253_D 2.013 0.99
248_S 256_V 1.906 0.99
122_L 141_I 1.899 0.99
25_S 34_M 1.843 0.99
25_S 29_A 1.835 0.99
30_Y 34_M 1.82 0.99
209_S 212_E 1.762 0.98
168_V 224_E 1.732 0.98
33_F 38_M 1.727 0.98
30_Y 35_T 1.677 0.97
232_S 243_A 1.642 0.97
20_G 23_H 1.59 0.96
30_Y 44_M 1.565 0.95
50_S 55_L 1.547 0.95
29_A 39_A 1.511 0.94
248_S 254_D 1.485 0.93
151_Q 261_S 1.455 0.92
24_G 27_K 1.452 0.92
52_P 56_I 1.429 0.91
23_H 28_I 1.4 0.90
24_G 45_W 1.395 0.90
24_G 29_A 1.395 0.90
270_E 274_L 1.394 0.90
115_L 148_L 1.388 0.90
177_R 224_E 1.387 0.90
25_S 38_M 1.377 0.89
180_A 230_L 1.371 0.89
212_E 219_N 1.363 0.89
112_Q 116_R 1.347 0.88
164_G 197_D 1.337 0.87
37_M 46_L 1.332 0.87
27_K 45_W 1.328 0.87
24_G 43_V 1.323 0.87
25_S 45_W 1.299 0.85
29_A 45_W 1.287 0.85
183_L 264_V 1.27 0.83
168_V 172_M 1.27 0.83
163_T 199_F 1.269 0.83
175_I 212_E 1.257 0.83
147_G 154_D 1.256 0.83
49_I 53_K 1.255 0.82
241_M 245_M 1.247 0.82
118_L 186_I 1.246 0.82
120_G 124_Q 1.236 0.81
49_I 52_P 1.231 0.81
249_D 253_D 1.22 0.80
75_R 78_N 1.219 0.80
49_I 59_A 1.219 0.80
62_F 65_P 1.217 0.80
222_R 238_V 1.215 0.80
173_R 224_E 1.205 0.79
154_D 160_M 1.201 0.78
79_S 87_G 1.19 0.78
29_A 36_A 1.187 0.77
221_S 260_I 1.186 0.77
176_L 221_S 1.181 0.77
152_I 175_I 1.18 0.77
58_I 61_Y 1.179 0.77
144_V 147_G 1.178 0.77
210_N 258_R 1.176 0.76
36_A 42_L 1.172 0.76
28_I 44_M 1.158 0.75
149_R 261_S 1.155 0.75
27_K 38_M 1.154 0.75
33_F 39_A 1.154 0.75
2_K 6_H 1.148 0.74
2_K 275_H 1.141 0.73
36_A 46_L 1.137 0.73
197_D 258_R 1.137 0.73
164_G 210_N 1.132 0.72
124_Q 127_E 1.129 0.72
28_I 33_F 1.128 0.72
184_N 234_K 1.128 0.72
95_G 205_E 1.126 0.72
192_L 219_N 1.119 0.71
86_G 96_E 1.106 0.70
29_A 46_L 1.104 0.70
246_R 252_P 1.104 0.70
142_D 151_Q 1.103 0.70
49_I 54_E 1.102 0.70
36_A 45_W 1.101 0.69
148_L 164_G 1.1 0.69
190_I 251_G 1.099 0.69
24_G 30_Y 1.091 0.68
198_D 252_P 1.088 0.68
106_L 110_M 1.086 0.68
37_M 240_G 1.086 0.68
163_T 197_D 1.086 0.68
212_E 225_L 1.082 0.68
27_K 36_A 1.078 0.67
274_L 277_N 1.077 0.67
83_I 86_G 1.077 0.67
46_L 61_Y 1.076 0.67
29_A 47_I 1.076 0.67
63_R 179_I 1.074 0.67
83_I 87_G 1.065 0.66
149_R 263_L 1.054 0.65
154_D 158_R 1.051 0.64
203_S 208_Y 1.048 0.64
219_N 222_R 1.048 0.64
35_T 39_A 1.043 0.63
40_F 59_A 1.041 0.63
42_L 46_L 1.04 0.63
172_M 261_S 1.04 0.63
29_A 34_M 1.039 0.63
271_Q 274_L 1.037 0.63
164_G 240_G 1.036 0.63
42_L 45_W 1.034 0.62
183_L 230_L 1.034 0.62
62_F 159_P 1.031 0.62
72_G 91_T 1.022 0.61
2_K 277_N 1.022 0.61
131_K 192_L 1.022 0.61
16_A 20_G 1.019 0.61
34_M 50_S 1.011 0.60
43_V 57_Q 1.01 0.60
198_D 253_D 1.007 0.59
39_A 47_I 1.006 0.59
24_G 36_A 1.005 0.59
113_S 116_R 1 0.59
250_R 254_D 1 0.59
4_Q 11_V 1 0.59
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2zovA10.68181000.59Contact Map0.54
2zvyA20.59421000.606Contact Map0.671
3khnA20.55191000.67Contact Map0.476
3s0yA20.61041000.67Contact Map0.393
4b62A10.50321000.698Contact Map0.475
3s06A20.52271000.709Contact Map0.412
2k1sA10.4741000.718Contact Map0.475
3ldtA10.53571000.722Contact Map0.383
3oonA10.389699.90.731Contact Map0.469
3cypB40.431899.90.737Contact Map0.413
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
Page generated in 0.0359 seconds.