| UniProt: | P0AE18 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10570 | ||
| Length: | 264 (253) | ||
| Sequences: | 7680 | ||
| Seq/Len: | 30.36 |
| MAP1
Paralog alert: 0.96 [within 20: 0.05] - ratio of genomes with paralogs Cluster includes: AMPP MAP1 PEPQ YPDF |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 15_R | 246_E | 4.323 | 1.00 | |
| 197_P | 242_D | 3.853 | 1.00 | |
| 140_V | 240_V | 2.973 | 1.00 | |
| 135_L | 156_F | 2.534 | 1.00 | |
| 23_E | 53_Q | 2.507 | 1.00 | |
| 122_G | 230_L | 2.491 | 1.00 | |
| 47_D | 51_N | 2.459 | 1.00 | |
| 11_I | 239_V | 2.436 | 1.00 | |
| 135_L | 138_R | 2.393 | 1.00 | |
| 154_Q | 158_E | 2.359 | 1.00 | |
| 16_V | 19_R | 2.355 | 1.00 | |
| 114_I | 118_P | 2.304 | 1.00 | |
| 157_V | 207_V | 2.254 | 1.00 | |
| 123_E | 127_R | 2.225 | 1.00 | |
| 127_R | 131_E | 2.198 | 1.00 | |
| 27_M | 48_Y | 2.152 | 1.00 | |
| 31_Y | 44_I | 2.104 | 1.00 | |
| 37_S | 87_L | 2.102 | 1.00 | |
| 13_K | 103_D | 2.058 | 1.00 | |
| 46_N | 50_V | 2.053 | 1.00 | |
| 119_T | 122_G | 2.04 | 1.00 | |
| 14_M | 200_T | 1.909 | 1.00 | |
| 27_M | 30_P | 1.904 | 1.00 | |
| 48_Y | 53_Q | 1.851 | 1.00 | |
| 120_I | 124_R | 1.851 | 1.00 | |
| 48_Y | 51_N | 1.85 | 1.00 | |
| 128_I | 160_E | 1.831 | 1.00 | |
| 156_F | 160_E | 1.781 | 1.00 | |
| 90_D | 117_K | 1.774 | 1.00 | |
| 208_N | 231_S | 1.756 | 1.00 | |
| 173_I | 237_T | 1.735 | 1.00 | |
| 24_V | 48_Y | 1.731 | 1.00 | |
| 44_I | 47_D | 1.728 | 1.00 | |
| 43_R | 47_D | 1.696 | 1.00 | |
| 217_M | 224_K | 1.687 | 1.00 | |
| 21_A | 109_T | 1.668 | 1.00 | |
| 130_Q | 134_Y | 1.653 | 1.00 | |
| 73_I | 86_K | 1.638 | 1.00 | |
| 145_N | 148_E | 1.617 | 1.00 | |
| 131_E | 135_L | 1.614 | 1.00 | |
| 136_A | 153_I | 1.587 | 1.00 | |
| 134_Y | 138_R | 1.565 | 1.00 | |
| 132_S | 156_F | 1.561 | 1.00 | |
| 150_G | 154_Q | 1.544 | 1.00 | |
| 27_M | 44_I | 1.544 | 1.00 | |
| 155_K | 159_A | 1.534 | 1.00 | |
| 39_G | 84_D | 1.533 | 1.00 | |
| 151_A | 155_K | 1.513 | 1.00 | |
| 195_L | 201_F | 1.507 | 1.00 | |
| 121_M | 124_R | 1.504 | 1.00 | |
| 34_P | 90_D | 1.485 | 1.00 | |
| 147_R | 192_N | 1.481 | 1.00 | |
| 16_V | 102_K | 1.456 | 1.00 | |
| 241_T | 244_G | 1.451 | 1.00 | |
| 239_V | 248_L | 1.448 | 1.00 | |
| 141_K | 144_I | 1.41 | 1.00 | |
| 88_L | 115_V | 1.403 | 0.99 | |
| 120_I | 123_E | 1.4 | 0.99 | |
| 27_M | 31_Y | 1.388 | 0.99 | |
| 139_M | 152_A | 1.387 | 0.99 | |
| 132_S | 157_V | 1.348 | 0.99 | |
| 139_M | 144_I | 1.337 | 0.99 | |
| 89_K | 92_D | 1.329 | 0.99 | |
| 124_R | 160_E | 1.325 | 0.99 | |
| 114_I | 126_C | 1.321 | 0.99 | |
| 29_E | 113_F | 1.316 | 0.99 | |
| 19_R | 23_E | 1.31 | 0.99 | |
| 58_A | 106_H | 1.306 | 0.99 | |
| 168_Y | 223_V | 1.306 | 0.99 | |
| 140_V | 203_I | 1.301 | 0.99 | |
| 5_I | 196_K | 1.299 | 0.99 | |
| 131_E | 160_E | 1.295 | 0.99 | |
| 33_K | 36_V | 1.283 | 0.99 | |
| 15_R | 19_R | 1.28 | 0.99 | |
| 105_F | 175_R | 1.277 | 0.99 | |
| 37_S | 40_E | 1.275 | 0.99 | |
| 8_P | 12_E | 1.273 | 0.99 | |
| 241_T | 246_E | 1.271 | 0.99 | |
| 86_K | 92_D | 1.263 | 0.99 | |
| 126_C | 234_Y | 1.257 | 0.99 | |
| 21_A | 107_G | 1.248 | 0.99 | |
| 142_P | 197_P | 1.245 | 0.98 | |
| 134_Y | 247_I | 1.223 | 0.98 | |
| 44_I | 48_Y | 1.221 | 0.98 | |
| 7_T | 10_D | 1.219 | 0.98 | |
| 75_E | 224_K | 1.215 | 0.98 | |
| 195_L | 240_V | 1.213 | 0.98 | |
| 28_I | 45_C | 1.211 | 0.98 | |
| 137_L | 238_I | 1.207 | 0.98 | |
| 20_L | 55_A | 1.2 | 0.98 | |
| 6_K | 179_E | 1.193 | 0.98 | |
| 108_D | 235_E | 1.179 | 0.98 | |
| 97_D | 108_D | 1.178 | 0.98 | |
| 136_A | 149_I | 1.178 | 0.98 | |
| 127_R | 130_Q | 1.171 | 0.98 | |
| 42_D | 46_N | 1.168 | 0.97 | |
| 16_V | 103_D | 1.165 | 0.97 | |
| 133_L | 137_L | 1.162 | 0.97 | |
| 131_E | 156_F | 1.157 | 0.97 | |
| 101_I | 106_H | 1.149 | 0.97 | |
| 200_T | 239_V | 1.134 | 0.97 | |
| 145_N | 194_V | 1.133 | 0.97 | |
| 18_G | 237_T | 1.128 | 0.97 | |
| 71_I | 94_V | 1.122 | 0.97 | |
| 133_L | 236_H | 1.119 | 0.96 | |
| 121_M | 211_K | 1.118 | 0.96 | |
| 20_L | 102_K | 1.105 | 0.96 | |
| 39_G | 43_R | 1.098 | 0.96 | |
| 45_C | 69_V | 1.096 | 0.96 | |
| 125_L | 212_K | 1.088 | 0.96 | |
| 36_V | 44_I | 1.087 | 0.96 | |
| 25_L | 113_F | 1.08 | 0.95 | |
| 151_A | 187_D | 1.065 | 0.95 | |
| 3_I | 193_V | 1.063 | 0.95 | |
| 32_V | 41_L | 1.062 | 0.95 | |
| 93_I | 122_G | 1.059 | 0.95 | |
| 23_E | 48_Y | 1.057 | 0.95 | |
| 136_A | 152_A | 1.056 | 0.95 | |
| 238_I | 245_C | 1.055 | 0.95 | |
| 168_Y | 216_T | 1.052 | 0.95 | |
| 22_A | 251_R | 1.05 | 0.94 | |
| 148_E | 151_A | 1.05 | 0.94 | |
| 165_V | 208_N | 1.045 | 0.94 | |
| 202_T | 237_T | 1.038 | 0.94 | |
| 119_T | 230_L | 1.034 | 0.94 | |
| 17_A | 107_G | 1.033 | 0.94 | |
| 144_I | 152_A | 1.032 | 0.94 | |
| 117_K | 123_E | 1.023 | 0.93 | |
| 97_D | 235_E | 1.022 | 0.93 | |
| 128_I | 156_F | 1.018 | 0.93 | |
| 77_V | 214_I | 1.017 | 0.93 | |
| 196_K | 199_M | 1.002 | 0.92 | |
| 20_L | 100_V | 1.001 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 4fo7A | 4 | 0.9962 | 100 | 0.102 | Contact Map | 0.783 |
| 3mx6A | 2 | 0.9773 | 100 | 0.11 | Contact Map | 0.795 |
| 2gg2A | 1 | 0.9962 | 100 | 0.116 | Contact Map | 0.823 |
| 3tb5A | 3 | 0.9886 | 100 | 0.117 | Contact Map | 0.833 |
| 3s6bA | 1 | 0.9924 | 100 | 0.121 | Contact Map | 0.835 |
| 4fukA | 2 | 0.9886 | 100 | 0.125 | Contact Map | 0.788 |
| 1o0xA | 1 | 0.947 | 100 | 0.126 | Contact Map | 0.818 |
| 3tavA | 2 | 0.947 | 100 | 0.135 | Contact Map | 0.715 |
| 3pkaA | 1 | 0.9432 | 100 | 0.139 | Contact Map | 0.763 |
| 2b3hA | 1 | 0.9811 | 100 | 0.139 | Contact Map | 0.824 |
Sequence Conservation (Image Generated using WebLogo v3)