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OPENSEQ.org

LPTG - Lipopolysaccharide export system permease protein LptG
UniProt: P0ADC6 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12536
Length: 360 (356)
Sequences: 2146
Seq/Len: 6.03

LPTG
Paralog alert: 0.90 [within 20: 0.44] - ratio of genomes with paralogs
Cluster includes: LPTF LPTG
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
193_A 208_Q 5.825 1.00
209_V 225_T 4.541 1.00
164_E 174_G 4.39 1.00
8_D 101_Q 3.027 1.00
276_W 342_L 2.877 1.00
194_T 207_S 2.824 1.00
171_E 194_T 2.707 1.00
82_M 86_R 2.591 1.00
7_L 92_M 2.552 1.00
165_R 173_G 2.527 1.00
181_N 185_R 2.417 1.00
262_K 272_Q 2.406 1.00
80_L 106_V 2.356 1.00
179_A 188_S 2.342 1.00
274_N 278_K 2.256 1.00
75_G 79_G 2.149 1.00
346_A 350_L 1.996 1.00
19_I 75_G 1.986 1.00
192_A 206_L 1.971 1.00
171_E 196_K 1.934 1.00
277_S 327_G 1.919 1.00
210_D 224_Q 1.907 1.00
110_A 289_M 1.892 1.00
255_H 275_M 1.892 1.00
196_K 207_S 1.856 1.00
198_D 205_R 1.848 1.00
205_R 227_S 1.796 1.00
127_Q 131_M 1.788 1.00
280_F 342_L 1.77 1.00
131_M 134_N 1.761 1.00
26_L 67_F 1.755 1.00
207_S 227_S 1.705 1.00
92_M 97_F 1.701 1.00
283_L 342_L 1.678 1.00
197_F 236_P 1.671 1.00
159_N 179_A 1.649 1.00
208_Q 226_V 1.637 1.00
13_K 17_T 1.635 1.00
350_L 354_W 1.622 1.00
83_L 92_M 1.584 0.99
9_R 13_K 1.559 0.99
72_A 285_V 1.551 0.99
203_V 229_T 1.548 0.99
120_I 124_V 1.531 0.99
287_V 348_F 1.526 0.99
284_S 319_F 1.51 0.99
58_L 128_G 1.507 0.99
336_P 339_I 1.506 0.99
42_A 52_A 1.505 0.99
114_V 286_A 1.49 0.99
61_P 69_P 1.485 0.99
5_G 9_R 1.478 0.99
205_R 229_T 1.472 0.99
330_T 340_G 1.467 0.99
115_L 119_A 1.467 0.99
57_L 61_P 1.465 0.99
190_R 211_E 1.455 0.99
192_A 195_A 1.441 0.99
23_L 71_A 1.434 0.99
14_T 82_M 1.43 0.99
188_S 211_E 1.427 0.99
111_I 115_L 1.415 0.98
150_Q 165_R 1.381 0.98
213_D 223_S 1.374 0.98
6_V 9_R 1.355 0.98
354_W 358_R 1.336 0.97
250_S 253_G 1.334 0.97
188_S 213_D 1.331 0.97
78_L 308_R 1.318 0.97
53_G 57_L 1.318 0.97
291_M 352_S 1.317 0.97
27_V 60_V 1.304 0.97
195_A 206_L 1.273 0.96
119_A 124_V 1.271 0.96
54_M 58_L 1.27 0.96
38_Q 56_T 1.266 0.96
73_L 288_M 1.266 0.96
23_L 64_V 1.265 0.96
19_I 71_A 1.264 0.96
71_A 75_G 1.261 0.96
273_L 278_K 1.261 0.96
311_T 315_F 1.254 0.96
7_L 10_Y 1.237 0.95
23_L 27_V 1.234 0.95
349_F 353_L 1.233 0.95
114_V 282_P 1.228 0.95
273_L 331_L 1.214 0.95
12_G 109_T 1.214 0.95
48_D 51_G 1.212 0.95
163_I 172_L 1.203 0.94
259_K 262_K 1.201 0.94
352_S 356_L 1.195 0.94
173_G 194_T 1.193 0.94
153_W 162_Y 1.187 0.94
11_I 92_M 1.178 0.94
167_K 171_E 1.176 0.94
69_P 94_A 1.164 0.93
286_A 347_S 1.161 0.93
177_I 206_L 1.158 0.93
175_I 195_A 1.157 0.93
55_Y 136_R 1.152 0.93
15_I 79_G 1.152 0.93
103_A 293_L 1.144 0.92
167_K 173_G 1.142 0.92
30_S 63_D 1.141 0.92
172_L 195_A 1.138 0.92
152_L 336_P 1.126 0.92
22_T 74_L 1.125 0.91
346_A 349_F 1.121 0.91
8_D 19_I 1.12 0.91
199_P 202_K 1.117 0.91
49_A 53_G 1.107 0.91
54_M 131_M 1.103 0.90
76_A 289_M 1.103 0.90
108_K 112_P 1.093 0.90
19_I 113_L 1.09 0.90
104_L 108_K 1.084 0.89
261_L 278_K 1.082 0.89
326_F 340_G 1.08 0.89
134_N 138_Q 1.075 0.89
18_T 79_G 1.075 0.89
258_V 265_G 1.073 0.89
31_G 56_T 1.07 0.89
10_Y 92_M 1.063 0.88
80_L 293_L 1.062 0.88
87_S 299_P 1.061 0.88
287_V 345_S 1.057 0.88
296_I 319_F 1.055 0.88
175_I 206_L 1.053 0.87
119_A 123_W 1.051 0.87
180_F 204_W 1.049 0.87
81_G 294_S 1.048 0.87
330_T 341_A 1.046 0.87
213_D 221_T 1.045 0.87
148_T 163_I 1.045 0.87
65_Q 121_G 1.045 0.87
34_K 38_Q 1.041 0.87
10_Y 69_P 1.041 0.87
225_T 228_G 1.04 0.87
349_F 352_S 1.037 0.86
268_A 272_Q 1.036 0.86
321_V 325_I 1.036 0.86
68_F 117_T 1.029 0.86
118_M 122_E 1.029 0.86
50_L 53_G 1.028 0.86
177_I 296_I 1.025 0.85
258_V 275_M 1.019 0.85
55_Y 59_S 1.015 0.85
6_V 10_Y 1.014 0.85
164_E 194_T 1.007 0.84
269_G 272_Q 1.007 0.84
74_L 91_V 1.006 0.84
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
3kcuA50.319411.70.965Contact Map0.481
4hfiA50.32784.40.971Contact Map0.263
4kytB20.09723.20.973Contact Map0.486
1fjkA10.09723.10.973Contact Map0.146
3j1zP20.255630.973Contact Map0.428
3klyA50.319430.973Contact Map0.541
3j1rA210.07222.50.974Contact Map0.49
1oedC10.23612.10.975Contact Map0.129
1oedB10.23611.90.976Contact Map0.126
1oedE10.23891.90.976Contact Map0.105

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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