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FLGG - Flagellar basal-body rod protein FlgG
UniProt: P0ABX5 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG14271
Length: 260 (260)
Sequences: 2358
Seq/Len: 9.07

FLGG
Paralog alert: 0.88 [within 20: 0.56] - ratio of genomes with paralogs
Cluster includes: FLGE FLGF FLGG
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
103_F 120_F 4.189 1.00
114_Y 178_F 3.82 1.00
95_V 151_I 3.432 1.00
152_G 156_V 3.383 1.00
95_V 214_L 3.122 1.00
130_T 134_F 3.041 1.00
123_D 127_Q 3.006 1.00
187_I 193_T 2.993 1.00
86_L 218_Y 2.963 1.00
86_L 96_A 2.842 1.00
127_Q 141_T 2.82 1.00
127_Q 135_Q 2.632 1.00
104_Q 176_T 2.624 1.00
81_H 102_F 2.603 1.00
105_V 115_T 2.511 1.00
204_S 211_A 2.508 1.00
185_E 195_T 2.434 1.00
151_I 157_V 2.342 1.00
97_I 175_L 2.291 1.00
36_R 229_E 2.211 1.00
128_L 136_V 2.18 1.00
159_V 170_V 2.168 1.00
100_Q 177_T 2.147 1.00
88_Q 218_Y 2.136 1.00
180_N 183_G 2.097 1.00
117_D 190_N 2.076 1.00
140_I 171_G 2.047 1.00
176_T 203_E 2.041 1.00
215_Y 218_Y 2.04 1.00
26_L 226_V 2.024 1.00
32_N 219_V 2.012 1.00
4_S 250_T 1.974 1.00
120_F 136_V 1.93 1.00
19_M 233_M 1.929 1.00
14_A 72_V 1.917 1.00
32_N 117_D 1.891 1.00
106_M 137_Q 1.86 1.00
194_E 200_A 1.851 1.00
18_N 236_V 1.817 1.00
185_E 193_T 1.794 1.00
252_Q 255_Q 1.778 1.00
95_V 103_F 1.777 1.00
123_D 129_V 1.767 1.00
97_I 212_G 1.75 1.00
107_L 113_A 1.743 1.00
19_M 236_V 1.73 1.00
37_Q 186_S 1.721 1.00
98_K 215_Y 1.688 1.00
87_S 221_T 1.665 1.00
32_N 119_S 1.658 1.00
89_T 94_D 1.651 1.00
177_T 211_A 1.625 1.00
225_N 228_E 1.624 1.00
22_I 236_V 1.618 1.00
105_V 130_T 1.58 1.00
18_N 232_N 1.574 1.00
128_L 140_I 1.54 1.00
95_V 173_L 1.531 1.00
113_A 187_I 1.526 1.00
117_D 131_A 1.515 1.00
207_G 213_L 1.502 1.00
93_K 128_L 1.499 1.00
152_G 158_S 1.495 1.00
104_Q 112_S 1.481 1.00
79_R 186_S 1.463 1.00
103_F 173_L 1.458 1.00
136_V 173_L 1.457 1.00
8_A 246_A 1.457 1.00
97_I 214_L 1.444 0.99
113_A 191_L 1.423 0.99
107_L 111_S 1.42 0.99
130_T 136_V 1.419 0.99
22_I 233_M 1.416 0.99
67_Q 186_S 1.399 0.99
9_K 12_L 1.379 0.99
34_F 37_Q 1.35 0.99
173_L 214_L 1.342 0.99
17_T 74_P 1.336 0.99
21_V 34_F 1.324 0.99
105_V 191_L 1.318 0.99
245_K 248_S 1.292 0.99
15_Q 239_A 1.285 0.99
93_K 149_I 1.276 0.98
16_Q 20_D 1.275 0.98
104_Q 137_Q 1.262 0.98
195_T 198_S 1.259 0.98
85_N 221_T 1.259 0.98
41_F 45_L 1.226 0.98
21_V 39_A 1.225 0.98
178_F 194_E 1.224 0.98
132_G 189_E 1.224 0.98
130_T 191_L 1.203 0.98
156_V 169_Q 1.2 0.97
36_R 228_E 1.198 0.97
108_P 134_F 1.194 0.97
248_S 251_D 1.19 0.97
138_P 174_N 1.188 0.97
251_D 254_L 1.183 0.97
15_Q 18_N 1.176 0.97
37_Q 79_R 1.168 0.97
91_N 94_D 1.133 0.96
24_N 34_F 1.13 0.96
93_K 122_V 1.13 0.96
57_S 60_T 1.122 0.96
95_V 216_Q 1.12 0.96
15_Q 236_V 1.115 0.96
105_V 120_F 1.061 0.94
95_V 136_V 1.058 0.94
247_V 251_D 1.058 0.94
198_S 201_P 1.056 0.94
36_R 80_L 1.045 0.93
149_I 157_V 1.04 0.93
232_N 235_Q 1.036 0.93
100_Q 181_D 1.025 0.92
172_Q 205_T 1.021 0.92
114_Y 201_P 1.02 0.92
38_R 78_E 1.013 0.92
19_M 253_M 1.005 0.91
102_F 192_Y 1.003 0.91
39_A 74_P 1.003 0.91
228_E 232_N 1.002 0.91
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3a69A10.91541000.127Contact Map0.77
1wlgA20.52311000.581Contact Map0.807
2x5pA10.43466.30.967Contact Map0.264
1oryB10.203860.967Contact Map0.614
2m4eA10.15382.30.973Contact Map0.531
1ucuA10.29622.10.974Contact Map0.52
3n3fA20.073120.974Contact Map0.506
4e45B60.251.50.976Contact Map0.289
3hshA60.08081.40.976Contact Map0.2
2hbpA10.23851.20.977Contact Map0.07

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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