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OPENSEQ.org
YMBA - Uncharacterized lipoprotein YmbA
UniProt: P0AB10 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13719
Length: 187 (186)
Sequences: 426
Seq/Len: 2.29
YMBA
Paralog alert: 0.07 [within 20: 0.01] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
133_V 175_E 2.647 1.00
91_L 118_V 2.276 1.00
81_S 89_N 2.262 1.00
152_L 171_V 2.173 1.00
131_V 164_M 1.939 0.99
87_L 172_W 1.928 0.99
98_Q 177_A 1.845 0.98
57_L 168_L 1.835 0.98
71_Y 80_A 1.832 0.98
65_Q 124_N 1.773 0.98
48_V 132_I 1.732 0.97
46_L 116_L 1.721 0.97
160_G 163_E 1.719 0.97
125_G 168_L 1.71 0.97
175_E 179_I 1.662 0.97
57_L 171_V 1.608 0.96
133_V 171_V 1.601 0.95
74_A 161_Y 1.553 0.94
123_F 168_L 1.539 0.94
67_S 70_K 1.523 0.94
91_L 176_A 1.521 0.94
48_V 149_P 1.502 0.93
15_G 157_T 1.443 0.91
68_D 166_K 1.431 0.90
122_E 134_S 1.431 0.90
124_N 168_L 1.387 0.89
168_L 171_V 1.345 0.86
90_T 169_A 1.325 0.85
46_L 139_L 1.324 0.85
62_V 165_V 1.323 0.85
152_L 175_E 1.317 0.85
25_Y 75_N 1.308 0.84
24_N 77_N 1.308 0.84
13_L 28_L 1.307 0.84
125_G 164_M 1.294 0.83
97_T 176_A 1.294 0.83
27_Q 81_S 1.286 0.83
74_A 125_G 1.276 0.82
81_S 86_Q 1.27 0.82
4_W 8_I 1.264 0.81
25_Y 76_N 1.255 0.81
135_G 175_E 1.251 0.81
52_T 119_T 1.23 0.79
154_G 170_G 1.226 0.79
93_A 131_V 1.224 0.78
131_V 140_N 1.211 0.77
64_Y 127_Y 1.196 0.76
130_K 153_E 1.195 0.76
80_A 160_G 1.182 0.75
120_V 179_I 1.177 0.75
53_V 84_D 1.172 0.74
162_D 181_Q 1.159 0.73
55_D 58_A 1.159 0.73
12_W 172_W 1.158 0.73
8_I 33_S 1.154 0.73
81_S 137_W 1.146 0.72
118_V 135_G 1.141 0.71
57_L 125_G 1.136 0.71
74_A 86_Q 1.127 0.70
103_V 148_R 1.126 0.70
58_A 83_L 1.121 0.69
61_G 74_A 1.12 0.69
129_G 168_L 1.118 0.69
35_T 38_T 1.115 0.69
99_L 180_A 1.106 0.68
82_P 135_G 1.084 0.66
91_L 169_A 1.083 0.65
80_A 95_L 1.082 0.65
65_Q 159_D 1.08 0.65
164_M 168_L 1.075 0.65
9_A 177_A 1.068 0.64
168_L 172_W 1.063 0.63
87_L 175_E 1.044 0.61
143_G 170_G 1.043 0.61
90_T 172_W 1.043 0.61
135_G 150_F 1.039 0.61
61_G 125_G 1.035 0.60
116_L 139_L 1.033 0.60
142_Q 181_Q 1.032 0.60
62_V 67_S 1.028 0.60
63_V 73_I 1.026 0.59
54_P 128_D 1.019 0.59
80_A 89_N 1.018 0.58
130_K 176_A 1.018 0.58
14_A 151_R 1.016 0.58
6_V 10_A 1.014 0.58
53_V 159_D 1.011 0.58
63_V 70_K 1.007 0.57
6_V 9_A 1.005 0.57
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2iqiA80.92511000.355Contact Map0.557
3zbiC140.256781.50.904Contact Map
2qguA10.941230.80.932Contact Map0.1
4kwyA20.61526.50.934Contact Map0.379
4k3vA20.871720.30.937Contact Map0.237
4fczB20.957217.50.939Contact Map0.128
2ylnA10.87177.40.948Contact Map0.128
1toaA20.82896.80.949Contact Map0.211
4av2M120.566860.951Contact Map0.272
2yjpA30.88245.40.952Contact Map0.157
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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