May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org
YCBC - Uncharacterized protein YcbC
UniProt: P0AB01 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12166
Length: 259 (252)
Sequences: 677
Seq/Len: 2.69
YCBC
Paralog alert: 0.07 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
116_W 155_Q 3.05 1.00
163_K 167_E 2.837 1.00
26_G 39_G 2.814 1.00
84_V 112_G 2.784 1.00
159_L 168_E 2.599 1.00
124_L 146_A 2.586 1.00
159_L 162_P 2.53 1.00
169_A 197_F 2.387 1.00
111_E 114_R 2.367 1.00
53_L 234_S 2.324 1.00
185_T 190_L 2.315 1.00
162_P 168_E 2.255 1.00
194_M 206_P 2.228 1.00
194_M 204_P 2.191 1.00
87_G 105_S 2.134 1.00
3_F 7_K 2.133 1.00
6_K 164_D 2.084 1.00
50_L 54_S 1.873 0.99
181_F 202_L 1.853 0.99
111_E 207_A 1.853 0.99
112_G 146_A 1.838 0.99
125_I 172_V 1.757 0.98
112_G 124_L 1.744 0.98
194_M 198_Q 1.724 0.98
186_S 210_N 1.707 0.98
168_E 172_V 1.676 0.98
165_T 168_E 1.669 0.98
116_W 152_P 1.665 0.98
26_G 43_I 1.65 0.97
66_I 241_T 1.641 0.97
83_V 181_F 1.603 0.97
143_A 158_T 1.58 0.96
127_T 162_P 1.565 0.96
113_I 146_A 1.564 0.96
196_F 247_Q 1.535 0.95
82_I 115_L 1.533 0.95
56_Q 230_W 1.529 0.95
140_E 160_D 1.528 0.95
116_W 119_N 1.525 0.95
168_E 171_A 1.515 0.95
67_E 187_A 1.507 0.95
70_Y 194_M 1.506 0.95
123_K 155_Q 1.505 0.95
173_K 177_G 1.502 0.95
16_L 235_D 1.498 0.95
162_P 172_V 1.475 0.94
125_I 175_A 1.456 0.93
62_L 234_S 1.449 0.93
136_V 144_R 1.417 0.92
23_I 46_G 1.417 0.92
159_L 171_A 1.412 0.92
62_L 237_V 1.412 0.92
82_I 184_V 1.383 0.91
187_A 211_Q 1.376 0.91
146_A 168_E 1.375 0.91
137_S 140_E 1.336 0.89
115_L 182_L 1.32 0.88
129_G 162_P 1.312 0.88
127_T 164_D 1.305 0.87
198_Q 203_N 1.299 0.87
191_P 194_M 1.298 0.87
21_L 25_A 1.294 0.87
137_S 160_D 1.272 0.86
193_A 206_P 1.268 0.85
55_L 58_V 1.264 0.85
162_P 165_T 1.254 0.84
114_R 148_S 1.234 0.83
106_L 246_W 1.233 0.83
190_L 209_A 1.23 0.83
19_M 49_A 1.227 0.83
52_L 58_V 1.222 0.82
63_L 237_V 1.212 0.82
54_S 231_L 1.194 0.80
119_N 122_S 1.177 0.79
87_G 104_N 1.166 0.78
81_Y 113_I 1.165 0.78
89_Y 138_T 1.164 0.78
127_T 158_T 1.162 0.78
187_A 191_P 1.157 0.77
165_T 169_A 1.157 0.77
3_F 6_K 1.156 0.77
159_L 172_V 1.154 0.77
162_P 171_A 1.149 0.77
159_L 165_T 1.147 0.76
82_I 116_W 1.145 0.76
126_F 142_G 1.138 0.76
65_P 237_V 1.135 0.75
182_L 206_P 1.129 0.75
66_I 244_R 1.119 0.74
6_K 10_G 1.112 0.73
181_F 204_P 1.109 0.73
188_S 236_R 1.108 0.73
67_E 208_P 1.097 0.72
246_W 250_K 1.092 0.71
182_L 247_Q 1.089 0.71
161_L 171_A 1.086 0.71
41_I 44_S 1.078 0.70
81_Y 181_F 1.078 0.70
166_E 247_Q 1.074 0.69
143_A 153_R 1.072 0.69
116_W 120_P 1.071 0.69
22_I 117_R 1.07 0.69
162_P 167_E 1.067 0.69
112_G 126_F 1.066 0.69
143_A 147_Q 1.052 0.67
37_K 48_L 1.052 0.67
138_T 168_E 1.05 0.67
114_R 118_E 1.05 0.67
190_L 206_P 1.041 0.66
40_K 84_V 1.034 0.65
123_K 157_I 1.034 0.65
211_Q 236_R 1.026 0.64
10_G 239_Y 1.024 0.64
159_L 176_I 1.014 0.63
146_A 159_L 1.011 0.63
69_T 191_P 1.01 0.62
129_G 138_T 1.01 0.62
42_F 49_A 1.008 0.62
156_I 165_T 1.004 0.62
138_T 162_P 1.002 0.62
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3ca8A20.76831000.548Contact Map0.502
4g4xA10.397725.20.957Contact Map0.365
2hqsH40.4131220.958Contact Map0.511
2kgwA10.440218.80.959Contact Map0.347
3ldtA10.579212.50.962Contact Map0.399
2pr7A20.50197.50.966Contact Map0.322
3td3A80.43247.40.966Contact Map0.407
3oonA10.43637.10.966Contact Map0.398
2aizP10.44796.60.967Contact Map0.385
3pzyA10.53286.50.967Contact Map0.232
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
Page generated in 0.0133 seconds.