OPENSEQ.org - YBGE - ECOLI GREMLIN

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YBGE - Uncharacterized protein YbgE

UniProt:	P0AAV0	Sequence MSKIIATLYAVMDKRPLRALSFVMALLLAGCMFWDPSRFAAKTSELEIWHGLLLMWAVCAGVIHGVGFRPQKVLWQGIFCPLLADIVLIVGLIFFFF	Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene:	EG12395
Length:	97 (96)
Sequences:	109
Seq/Len:	1.14

YBGE
Paralog alert: 0.00 [within 20: 0.00] - ratio of genomes with paralogs

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Scaled Score	Prob
60_A	63_I	2.11	0.98
86_I	89_I	1.876	0.94
71_Q	89_I	1.765	0.92
21_S	64_H	1.635	0.87
7_T	23_V	1.621	0.86
23_V	85_D	1.602	0.86
32_M	55_M	1.557	0.83
16_P	20_L	1.552	0.83
71_Q	96_F	1.523	0.81
41_A	44_S	1.52	0.81
73_V	78_I	1.453	0.77
52_L	75_W	1.443	0.76
6_A	76_Q	1.433	0.76
7_T	27_L	1.372	0.71
50_H	83_L	1.317	0.67
20_L	56_W	1.293	0.64
38_R	58_V	1.287	0.64
3_K	11_V	1.274	0.63
18_R	22_F	1.267	0.62
72_K	83_L	1.254	0.61
8_L	64_H	1.247	0.60
70_P	88_L	1.238	0.59
52_L	77_G	1.223	0.58
31_C	38_R	1.218	0.58
17_L	27_L	1.214	0.57
36_P	70_P	1.211	0.57
28_L	33_F	1.208	0.57
34_W	59_C	1.169	0.53
16_P	29_A	1.165	0.53
33_F	46_L	1.161	0.52
39_F	92_L	1.154	0.52
55_M	75_W	1.143	0.50
24_M	75_W	1.132	0.49
15_R	19_A	1.111	0.47
47_E	78_I	1.088	0.45
35_D	57_A	1.087	0.45
18_R	56_W	1.083	0.45
26_L	30_G	1.069	0.43
35_D	66_V	1.049	0.42
36_P	59_C	1.041	0.41
61_G	84_A	1.035	0.40
75_W	79_F	1.028	0.40
34_W	57_A	1.027	0.39
2_S	7_T	1.025	0.39
40_A	51_G	1.02	0.39
3_K	7_T	1.013	0.38
63_I	71_Q	1.008	0.38
30_G	54_L	1.004	0.37

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling

HHsearch Results:

PDB	Chains	Cov	P(%)	HHΔ		Acc
2a65A	1	0.9897	29.3	0.912	Contact Map	0.136
4m48A	1	0.9897	26	0.915	Contact Map	0.031
1vsy5	2	0.9485	3.6	0.942	Contact Map	0.05
1ji8A	1	0.3402	3.5	0.943	Contact Map	0.06
1m0kA	1	0.7423	3.2	0.944	Contact Map	0.099
4djkA	2	0.9691	3.1	0.944	Contact Map	0.236
3or1C	2	0.3402	3.1	0.944	Contact Map	0.402
1n2mA	6	0.3711	2.7	0.946	Contact Map	0.066
3l1lA	1	0.9381	2	0.95	Contact Map	0.15
1sauA	1	0.3402	1.9	0.95	Contact Map	0.483

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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