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OPENSEQ.org

YRBA - Uncharacterized protein YrbA
UniProt: P0A9W6 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12796
Length: 84 (78)
Sequences: 1511
Seq/Len: 19.37

YRBA
Paralog alert: 0.81 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: BOLA YRBA
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
7_Q 11_M 3.241 1.00
40_M 48_T 2.875 1.00
40_M 44_K 2.482 1.00
8_S 12_N 2.307 1.00
35_E 38_D 2.219 1.00
45_K 74_E 2.148 1.00
9_V 56_Y 2.105 1.00
38_D 73_A 1.916 1.00
50_Y 57_I 1.898 1.00
43_V 47_Q 1.836 1.00
4_N 7_Q 1.809 1.00
35_E 72_P 1.802 1.00
57_I 62_I 1.748 1.00
20_H 31_I 1.617 1.00
16_L 19_V 1.573 1.00
41_S 44_K 1.556 1.00
31_I 70_Y 1.552 1.00
54_M 58_A 1.548 1.00
29_Q 68_K 1.538 1.00
22_S 29_Q 1.48 1.00
31_I 68_K 1.389 0.99
14_L 48_T 1.383 0.99
70_Y 75_W 1.367 0.99
44_K 47_Q 1.351 0.99
13_A 52_P 1.284 0.99
14_L 32_A 1.274 0.99
46_Q 67_I 1.206 0.98
43_V 50_Y 1.194 0.98
21_V 30_V 1.184 0.98
3_N 7_Q 1.16 0.97
47_Q 50_Y 1.158 0.97
4_N 8_S 1.125 0.97
73_A 77_R 1.103 0.96
47_Q 51_G 1.087 0.96
15_S 36_L 1.083 0.96
45_K 69_A 1.08 0.95
32_A 69_A 1.068 0.95
56_Y 61_R 1.039 0.94
5_E 8_S 1.032 0.94
33_V 71_T 1.011 0.93
24_D 27_H 1.001 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1ny8A111000.039Contact Map0.569
3tr3A20.916799.90.101Contact Map0.759
2dhmA10.988199.90.109Contact Map0.563
2kdnA10.964399.90.114Contact Map0.621
1v9jA10.940599.90.118Contact Map0.645
3o2eA10.940599.90.119Contact Map0.741
1xs3A10.88199.90.122Contact Map0.291
1v60A10.988199.90.124Contact Map0.667
2mcqA10.857199.90.158Contact Map0.563
2kz0A10.809599.90.206Contact Map0.479

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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