| UniProt: | P0A9U8 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13974 | ||
| Length: | 383 (378) | ||
| Sequences: | 15279 | ||
| Seq/Len: | 40.42 |
| YDIO
Paralog alert: 0.77 [within 20: 0.28] - ratio of genomes with paralogs Cluster includes: CAIA YDIO |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 150_N | 215_N | 3.963 | 1.00 | |
| 146_K | 217_E | 3.881 | 1.00 | |
| 23_N | 45_A | 3.485 | 1.00 | |
| 290_K | 328_E | 3.41 | 1.00 | |
| 103_E | 107_K | 3.313 | 1.00 | |
| 112_T | 117_D | 3.037 | 1.00 | |
| 194_K | 214_D | 2.981 | 1.00 | |
| 142_R | 220_E | 2.946 | 1.00 | |
| 30_R | 35_N | 2.83 | 1.00 | |
| 143_K | 217_E | 2.8 | 1.00 | |
| 262_R | 266_Q | 2.79 | 1.00 | |
| 182_T | 223_M | 2.711 | 1.00 | |
| 66_D | 69_T | 2.576 | 1.00 | |
| 283_K | 332_D | 2.525 | 1.00 | |
| 17_R | 76_E | 2.498 | 1.00 | |
| 112_T | 118_P | 2.496 | 1.00 | |
| 264_A | 336_I | 2.363 | 1.00 | |
| 226_E | 229_M | 2.311 | 1.00 | |
| 18_E | 22_T | 2.226 | 1.00 | |
| 103_E | 106_R | 2.152 | 1.00 | |
| 152_Q | 212_Y | 2.148 | 1.00 | |
| 102_A | 105_L | 2.145 | 1.00 | |
| 273_P | 276_H | 2.111 | 1.00 | |
| 254_E | 295_R | 2.084 | 1.00 | |
| 57_P | 98_R | 2.035 | 1.00 | |
| 303_W | 307_Q | 1.938 | 1.00 | |
| 344_D | 349_S | 1.923 | 1.00 | |
| 44_R | 48_D | 1.919 | 1.00 | |
| 169_A | 184_W | 1.916 | 1.00 | |
| 143_K | 146_K | 1.911 | 1.00 | |
| 229_M | 232_L | 1.902 | 1.00 | |
| 6_T | 9_Q | 1.9 | 1.00 | |
| 45_A | 48_D | 1.897 | 1.00 | |
| 142_R | 227_E | 1.835 | 1.00 | |
| 107_K | 111_S | 1.804 | 1.00 | |
| 148_Y | 217_E | 1.781 | 1.00 | |
| 75_M | 295_R | 1.771 | 1.00 | |
| 268_I | 273_P | 1.734 | 1.00 | |
| 257_F | 291_I | 1.721 | 1.00 | |
| 147_V | 220_E | 1.71 | 1.00 | |
| 190_K | 216_V | 1.708 | 1.00 | |
| 219_E | 222_D | 1.701 | 1.00 | |
| 10_E | 13_L | 1.695 | 1.00 | |
| 349_S | 353_R | 1.682 | 1.00 | |
| 76_E | 79_K | 1.674 | 1.00 | |
| 293_N | 321_Y | 1.665 | 1.00 | |
| 279_M | 282_E | 1.662 | 1.00 | |
| 259_D | 347_R | 1.641 | 1.00 | |
| 79_K | 258_E | 1.636 | 1.00 | |
| 152_Q | 210_E | 1.629 | 1.00 | |
| 254_E | 258_E | 1.624 | 1.00 | |
| 11_L | 14_A | 1.617 | 1.00 | |
| 223_M | 227_E | 1.615 | 1.00 | |
| 149_I | 184_W | 1.607 | 1.00 | |
| 125_T | 155_F | 1.605 | 1.00 | |
| 324_R | 365_D | 1.605 | 1.00 | |
| 159_A | 209_C | 1.601 | 1.00 | |
| 264_A | 280_I | 1.592 | 1.00 | |
| 165_M | 188_S | 1.589 | 1.00 | |
| 143_K | 148_Y | 1.575 | 1.00 | |
| 14_A | 18_E | 1.573 | 1.00 | |
| 9_Q | 69_T | 1.567 | 1.00 | |
| 108_T | 221_S | 1.55 | 1.00 | |
| 272_K | 276_H | 1.545 | 1.00 | |
| 108_T | 112_T | 1.542 | 1.00 | |
| 294_M | 322_C | 1.542 | 1.00 | |
| 172_P | 175_K | 1.532 | 1.00 | |
| 147_V | 184_W | 1.53 | 1.00 | |
| 104_Q | 108_T | 1.522 | 1.00 | |
| 112_T | 115_T | 1.518 | 1.00 | |
| 145_G | 217_E | 1.512 | 1.00 | |
| 141_T | 150_N | 1.506 | 1.00 | |
| 150_N | 214_D | 1.506 | 1.00 | |
| 11_L | 15_S | 1.505 | 1.00 | |
| 40_R | 44_R | 1.502 | 1.00 | |
| 34_Q | 199_H | 1.491 | 1.00 | |
| 340_L | 346_A | 1.483 | 1.00 | |
| 121_A | 165_M | 1.477 | 1.00 | |
| 269_A | 277_N | 1.476 | 1.00 | |
| 286_L | 369_I | 1.475 | 1.00 | |
| 259_D | 262_R | 1.471 | 1.00 | |
| 145_G | 220_E | 1.47 | 1.00 | |
| 320_L | 365_D | 1.464 | 1.00 | |
| 58_E | 64_P | 1.458 | 1.00 | |
| 104_Q | 221_S | 1.454 | 1.00 | |
| 287_M | 329_V | 1.441 | 1.00 | |
| 220_E | 223_M | 1.441 | 1.00 | |
| 280_I | 336_I | 1.437 | 1.00 | |
| 160_K | 209_C | 1.435 | 1.00 | |
| 148_Y | 215_N | 1.433 | 1.00 | |
| 7_E | 11_L | 1.408 | 1.00 | |
| 60_F | 106_R | 1.405 | 0.99 | |
| 255_C | 259_D | 1.403 | 0.99 | |
| 54_L | 73_A | 1.402 | 0.99 | |
| 104_Q | 107_K | 1.398 | 0.99 | |
| 187_D | 190_K | 1.395 | 0.99 | |
| 142_R | 146_K | 1.394 | 0.99 | |
| 13_L | 76_E | 1.392 | 0.99 | |
| 256_A | 330_I | 1.381 | 0.99 | |
| 300_K | 304_Q | 1.373 | 0.99 | |
| 194_K | 212_Y | 1.368 | 0.99 | |
| 292_D | 300_K | 1.363 | 0.99 | |
| 146_K | 220_E | 1.346 | 0.99 | |
| 331_D | 359_R | 1.325 | 0.99 | |
| 9_Q | 66_D | 1.317 | 0.99 | |
| 253_A | 291_I | 1.312 | 0.99 | |
| 100_G | 236_Y | 1.311 | 0.99 | |
| 328_E | 332_D | 1.308 | 0.99 | |
| 113_L | 120_Y | 1.3 | 0.99 | |
| 190_K | 222_D | 1.298 | 0.99 | |
| 147_V | 227_E | 1.294 | 0.99 | |
| 80_C | 83_P | 1.293 | 0.99 | |
| 187_D | 222_D | 1.293 | 0.99 | |
| 304_Q | 314_S | 1.288 | 0.99 | |
| 193_I | 211_V | 1.283 | 0.99 | |
| 16_I | 51_I | 1.279 | 0.99 | |
| 128_G | 137_T | 1.276 | 0.99 | |
| 218_V | 222_D | 1.273 | 0.99 | |
| 111_S | 115_T | 1.271 | 0.99 | |
| 27_E | 32_C | 1.271 | 0.99 | |
| 196_N | 212_Y | 1.269 | 0.99 | |
| 199_H | 344_D | 1.262 | 0.99 | |
| 291_I | 329_V | 1.254 | 0.99 | |
| 44_R | 117_D | 1.249 | 0.99 | |
| 294_M | 325_T | 1.247 | 0.99 | |
| 283_K | 366_E | 1.241 | 0.98 | |
| 15_S | 49_N | 1.227 | 0.98 | |
| 149_I | 167_V | 1.225 | 0.98 | |
| 9_Q | 72_L | 1.22 | 0.98 | |
| 287_M | 332_D | 1.219 | 0.98 | |
| 27_E | 30_R | 1.217 | 0.98 | |
| 123_A | 156_I | 1.215 | 0.98 | |
| 257_F | 261_A | 1.214 | 0.98 | |
| 10_E | 14_A | 1.214 | 0.98 | |
| 259_D | 337_M | 1.213 | 0.98 | |
| 188_S | 193_I | 1.209 | 0.98 | |
| 32_C | 205_M | 1.208 | 0.98 | |
| 196_N | 210_E | 1.207 | 0.98 | |
| 333_A | 348_V | 1.203 | 0.98 | |
| 172_P | 176_D | 1.201 | 0.98 | |
| 300_K | 303_W | 1.193 | 0.98 | |
| 65_A | 69_T | 1.19 | 0.98 | |
| 142_R | 147_V | 1.187 | 0.98 | |
| 47_A | 52_S | 1.18 | 0.98 | |
| 327_M | 359_R | 1.178 | 0.98 | |
| 253_A | 329_V | 1.177 | 0.98 | |
| 304_Q | 309_Q | 1.175 | 0.98 | |
| 45_A | 49_N | 1.174 | 0.98 | |
| 191_P | 217_E | 1.174 | 0.98 | |
| 255_C | 351_F | 1.173 | 0.98 | |
| 101_S | 105_L | 1.169 | 0.97 | |
| 79_K | 254_E | 1.166 | 0.97 | |
| 331_D | 356_R | 1.164 | 0.97 | |
| 250_T | 291_I | 1.159 | 0.97 | |
| 19_L | 45_A | 1.158 | 0.97 | |
| 75_M | 299_L | 1.157 | 0.97 | |
| 56_V | 114_E | 1.154 | 0.97 | |
| 247_A | 298_V | 1.152 | 0.97 | |
| 231_F | 235_M | 1.15 | 0.97 | |
| 260_A | 333_A | 1.142 | 0.97 | |
| 324_R | 328_E | 1.14 | 0.97 | |
| 106_R | 110_E | 1.139 | 0.97 | |
| 44_R | 47_A | 1.137 | 0.97 | |
| 272_K | 277_N | 1.134 | 0.97 | |
| 59_E | 107_K | 1.131 | 0.97 | |
| 16_I | 20_I | 1.125 | 0.97 | |
| 261_A | 265_N | 1.124 | 0.97 | |
| 290_K | 325_T | 1.116 | 0.96 | |
| 15_S | 51_I | 1.115 | 0.96 | |
| 141_T | 148_Y | 1.115 | 0.96 | |
| 138_T | 149_I | 1.115 | 0.96 | |
| 289_I | 317_L | 1.107 | 0.96 | |
| 68_V | 303_W | 1.1 | 0.96 | |
| 139_T | 150_N | 1.098 | 0.96 | |
| 140_Y | 184_W | 1.093 | 0.96 | |
| 327_M | 331_D | 1.074 | 0.95 | |
| 67_Y | 306_D | 1.064 | 0.95 | |
| 17_R | 21_T | 1.063 | 0.95 | |
| 7_E | 10_E | 1.062 | 0.95 | |
| 126_E | 153_K | 1.062 | 0.95 | |
| 188_S | 195_I | 1.059 | 0.95 | |
| 105_L | 109_A | 1.057 | 0.95 | |
| 165_M | 193_I | 1.053 | 0.95 | |
| 193_I | 216_V | 1.051 | 0.94 | |
| 167_V | 213_L | 1.043 | 0.94 | |
| 120_Y | 164_Y | 1.032 | 0.94 | |
| 167_V | 186_V | 1.029 | 0.94 | |
| 192_G | 216_V | 1.022 | 0.93 | |
| 330_I | 355_V | 1.021 | 0.93 | |
| 326_A | 355_V | 1.018 | 0.93 | |
| 105_L | 185_W | 1.013 | 0.93 | |
| 13_L | 72_L | 1.013 | 0.93 | |
| 75_M | 254_E | 1.012 | 0.93 | |
| 168_L | 183_L | 1.011 | 0.93 | |
| 163_P | 189_S | 1.008 | 0.93 | |
| 136_A | 181_F | 1.008 | 0.93 | |
| 327_M | 352_W | 1.006 | 0.93 | |
| 239_E | 312_R | 1.006 | 0.93 | |
| 264_A | 284_L | 1.004 | 0.93 | |
| 288_A | 292_D | 1.003 | 0.93 | |
| 359_R | 365_D | 1 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 4ktoA | 4 | 0.9896 | 100 | 0.065 | Contact Map | 0.78 |
| 2d29A | 2 | 0.9869 | 100 | 0.071 | Contact Map | 0.784 |
| 1egdA | 4 | 0.9948 | 100 | 0.072 | Contact Map | 0.88 |
| 1ivhA | 4 | 0.9896 | 100 | 0.074 | Contact Map | 0.809 |
| 2jifA | 4 | 0.9843 | 100 | 0.074 | Contact Map | 0.818 |
| 1ukwA | 2 | 0.9843 | 100 | 0.077 | Contact Map | 0.808 |
| 1bucA | 2 | 0.9817 | 100 | 0.08 | Contact Map | 0.828 |
| 3pfdA | 4 | 0.9817 | 100 | 0.081 | Contact Map | 0.819 |
| 4m9aA | 4 | 0.9765 | 100 | 0.081 | Contact Map | 0.822 |
| 4n5fA | 2 | 0.9765 | 100 | 0.081 | Contact Map | 0.778 |
Sequence Conservation (Image Generated using WebLogo v3)