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OPENSEQ.org

YBAQ - Uncharacterized HTH-type transcriptional regulator YbaQ
UniProt: P0A9T6 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13245
Length: 113 (98)
Sequences: 760
Seq/Len: 7.76

YBAQ
Paralog alert: 0.53 [within 20: 0.02] - ratio of genomes with paralogs
Cluster includes: YBAQ YDDM
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
72_N 76_A 2.837 1.00
40_S 55_M 2.661 1.00
43_A 49_R 2.367 1.00
28_N 32_E 2.192 1.00
29_E 33_L 2.162 1.00
27_I 42_S 2.088 1.00
33_L 62_V 2.007 1.00
17_Y 21_E 1.997 1.00
60_A 67_V 1.976 1.00
28_N 38_R 1.84 1.00
60_A 66_T 1.788 1.00
80_W 84_N 1.761 1.00
62_V 98_V 1.683 1.00
39_N 42_S 1.672 1.00
39_N 43_A 1.585 1.00
88_T 92_L 1.557 1.00
19_Y 22_P 1.544 1.00
42_S 46_N 1.518 1.00
56_A 67_V 1.461 0.99
6_R 80_W 1.435 0.99
60_A 65_T 1.415 0.99
36_V 55_M 1.376 0.99
27_I 39_N 1.363 0.99
8_P 81_E 1.326 0.98
16_L 21_E 1.318 0.98
43_A 48_N 1.313 0.98
57_F 82_V 1.307 0.98
65_T 69_F 1.267 0.98
50_K 78_D 1.264 0.98
38_R 42_S 1.237 0.97
61_K 97_T 1.226 0.97
30_L 59_L 1.196 0.96
9_T 14_I 1.188 0.96
37_H 40_S 1.146 0.95
56_A 68_D 1.143 0.95
44_L 55_M 1.115 0.94
13_D 17_Y 1.11 0.94
27_I 41_V 1.105 0.94
36_V 40_S 1.103 0.94
68_D 83_E 1.1 0.94
20_L 25_L 1.096 0.93
10_T 47_N 1.067 0.92
25_L 30_L 1.065 0.92
10_T 77_V 1.055 0.92
6_R 9_T 1.054 0.92
77_V 81_E 1.039 0.91
16_L 45_I 1.033 0.91
67_V 83_E 1.027 0.90
40_S 54_E 1.005 0.89
62_V 95_I 1.004 0.89
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2ebyA2199.60.58Contact Map0.792
3trbA20.88599.50.607Contact Map0.746
3cecA10.849699.50.622Contact Map0.681
2ictA10.831999.40.643Contact Map0.52
2b5aA40.681498.70.733Contact Map0.82
3fmyA10.637298.70.735Contact Map0.451
2a6cA20.654998.60.741Contact Map0.541
3g7dA10.991298.60.743Contact Map0.481
4f8dA20.716898.60.745Contact Map0.56
3o9xA20.637298.50.745Contact Map0.443

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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