OPENSEQ.org - YACL - ECOLI GREMLIN

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YACL - UPF0231 protein YacL

UniProt:	P0A8E5	Sequence MDYEFLRDITGVVKVRMSMGHEVVGHWFNEEVKENLALLDEVEQAAHALKGSERSWQRAGHEYTLWMDGEEVMVRANQLEFAGDEMEEGMNYYDEESLSLCGVEDFLQVVAAYRNFVQQK	Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene:	EG12605
Length:	120 (120)
Sequences:	131
Seq/Len:	1.09

YACL
Paralog alert: 0.00 [within 20: 0.00] - ratio of genomes with paralogs

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Scaled Score	Prob
35_N	38_L	1.884	0.94
6_L	16_R	1.837	0.93
93_Y	96_E	1.788	0.92
19_M	93_Y	1.786	0.92
37_A	74_V	1.712	0.89
19_M	96_E	1.693	0.89
104_E	109_V	1.532	0.81
85_E	103_V	1.503	0.79
2_D	108_Q	1.488	0.78
17_M	109_V	1.475	0.77
1_M	5_F	1.461	0.76
73_M	113_Y	1.448	0.75
42_V	110_V	1.439	0.75
17_M	58_R	1.424	0.74
3_Y	17_M	1.418	0.73
29_N	113_Y	1.41	0.73
28_F	112_A	1.377	0.70
68_D	89_G	1.376	0.70
18_S	21_H	1.368	0.69
23_V	55_S	1.363	0.69
2_D	20_G	1.353	0.68
41_E	58_R	1.342	0.67
49_L	67_M	1.333	0.67
4_E	9_I	1.327	0.66
67_M	72_V	1.325	0.66
28_F	32_V	1.32	0.65
103_V	110_V	1.291	0.63
2_D	82_A	1.224	0.57
25_G	30_E	1.221	0.57
19_M	97_S	1.216	0.56
110_V	117_V	1.21	0.55
36_L	61_H	1.2	0.55
13_V	29_N	1.197	0.54
29_N	63_Y	1.189	0.54
15_V	110_V	1.174	0.52
72_V	84_D	1.172	0.52
17_M	110_V	1.151	0.50
17_M	42_V	1.137	0.49
33_K	113_Y	1.133	0.48
39_L	43_E	1.126	0.48
74_V	96_E	1.121	0.47
62_E	71_E	1.114	0.46
56_W	70_E	1.109	0.46
57_Q	104_E	1.101	0.45
79_L	87_E	1.096	0.45
111_A	115_N	1.087	0.44
35_N	110_V	1.087	0.44
28_F	109_V	1.076	0.43
55_S	64_T	1.072	0.42
25_G	87_E	1.072	0.42
47_H	86_M	1.063	0.42
38_L	106_F	1.061	0.41
72_V	106_F	1.05	0.40
28_F	42_V	1.049	0.40
82_A	115_N	1.038	0.39
80_E	110_V	1.033	0.39
110_V	119_Q	1.028	0.38
32_V	71_E	1.024	0.38
37_A	118_Q	1.017	0.37
78_Q	113_Y	1.017	0.37
103_V	112_A	1.014	0.37
23_V	41_E	1.014	0.37
53_E	61_H	1.013	0.37
32_V	92_Y	1.009	0.37
3_Y	50_K	1.007	0.37
2_D	92_Y	1.004	0.36
103_V	107_L	1.004	0.36
9_I	14_K	1	0.36

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling

HHsearch Results:

PDB	Chains	Cov	P(%)	HHΔ		Acc
1q67A	2	0.4167	8.2	0.947	Contact Map	0.178
4kmdA	1	0.625	6.9	0.949	Contact Map	0.164
2q2kA	2	0.2667	6.5	0.95	Contact Map	0.166
1uqvA	1	0.425	6.5	0.95	Contact Map	0.195
2lydA	1	0.3667	5.9	0.951	Contact Map	0.091
1dvoA	1	0.3917	5.4	0.952	Contact Map	0.195
4b6hA	2	0.375	3.6	0.955	Contact Map	0.253
2z02A	2	0.375	3.3	0.956	Contact Map	0
4fe2A	2	0.3833	3.2	0.956	Contact Map	0.002
1nwdB	2	0.2083	3.1	0.957	Contact Map	0.095

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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