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OPENSEQ.org

RL10 - 50S ribosomal protein L10
UniProt: P0A7J3 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10871
Length: 165 (164)
Sequences: 1446
Seq/Len: 8.82

RL10
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
119_P 122_Q 3.355 1.00
18_V 51_Y 2.754 1.00
75_A 110_A 2.697 1.00
156_A 160_D 2.668 1.00
16_S 66_G 2.366 1.00
156_A 159_R 2.355 1.00
121_S 124_D 2.246 1.00
132_Y 136_I 2.226 1.00
62_R 65_E 2.213 1.00
124_D 128_T 2.209 1.00
134_E 138_R 2.201 1.00
16_S 20_K 2.2 1.00
44_A 98_E 2.031 1.00
97_K 124_D 2.005 1.00
29_D 107_E 1.943 1.00
40_E 44_A 1.877 1.00
44_A 47_E 1.864 1.00
5_L 9_Q 1.86 1.00
131_T 135_A 1.815 1.00
65_E 70_E 1.795 1.00
37_K 103_N 1.77 1.00
113_F 118_I 1.75 1.00
149_G 153_R 1.734 1.00
17_E 21_G 1.721 1.00
98_E 101_K 1.715 1.00
138_R 141_A 1.699 1.00
158_V 162_K 1.637 1.00
6_Q 9_Q 1.622 1.00
116_E 122_Q 1.62 1.00
97_K 128_T 1.61 1.00
15_V 55_V 1.592 1.00
28_A 81_L 1.55 1.00
34_T 37_K 1.55 1.00
44_A 102_A 1.546 1.00
41_L 99_F 1.517 1.00
17_E 20_K 1.493 1.00
13_A 17_E 1.473 1.00
120_A 124_D 1.47 1.00
31_R 79_P 1.407 0.99
5_L 8_K 1.402 0.99
21_G 86_M 1.386 0.99
28_A 52_M 1.378 0.99
137_A 141_A 1.37 0.99
99_F 103_N 1.358 0.99
150_K 154_T 1.349 0.99
55_V 60_L 1.34 0.99
158_V 161_A 1.327 0.99
36_D 40_E 1.317 0.99
159_R 162_K 1.288 0.98
9_Q 12_V 1.282 0.98
52_M 81_L 1.274 0.98
98_E 102_A 1.264 0.98
90_G 94_R 1.251 0.98
19_A 60_L 1.25 0.98
38_M 52_M 1.244 0.98
145_E 149_G 1.239 0.98
144_K 147_S 1.231 0.98
38_M 81_L 1.213 0.98
150_K 153_R 1.213 0.98
49_G 87_E 1.205 0.97
140_M 143_M 1.195 0.97
71_C 117_L 1.186 0.97
146_A 149_G 1.177 0.97
146_A 150_K 1.168 0.97
16_S 67_T 1.165 0.97
45_G 50_V 1.159 0.97
131_T 134_E 1.152 0.96
19_A 64_V 1.15 0.96
139_L 143_M 1.145 0.96
61_R 73_K 1.131 0.96
33_V 103_N 1.126 0.96
43_K 47_E 1.102 0.95
139_L 142_T 1.1 0.95
18_V 84_Y 1.097 0.95
10_A 14_E 1.08 0.94
60_L 82_I 1.071 0.94
29_D 109_K 1.069 0.94
133_E 136_I 1.067 0.94
122_Q 125_R 1.062 0.94
97_K 127_A 1.048 0.93
136_I 158_V 1.047 0.93
76_F 82_I 1.038 0.93
159_R 163_E 1.033 0.92
66_G 70_E 1.03 0.92
124_D 127_A 1.019 0.92
27_V 80_T 1.017 0.92
27_V 72_L 1.014 0.91
45_G 81_L 1.006 0.91
151_L 155_L 1.006 0.91
96_F 106_F 1.004 0.91
71_C 74_D 1.001 0.91
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
4kix510.99391000.124Contact Map0.194
1zavA10.98791000.176Contact Map0.631
2j01J10.96361000.181Contact Map
4hubG10.981899.90.518Contact Map0.448
3a1yG10.939499.90.526Contact Map0.436
1vq8G10.878899.90.528Contact Map0.609
3u5iq10.969799.90.533Contact Map0.491
3j21k10.884899.90.535Contact Map0.441
3iz5s10.969799.90.55Contact Map0.28
3jsyA20.963699.90.552Contact Map0.525

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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