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cI_B_6_cIII_cytb_6_Pdenitr

Genes: A B A+B
Length: 175 440 578
Sequences: 1602 3299 471
Seq/Len: 9.15 7.5 0.81
MirrorTree (Pazo et al. 2001) 0.21
Download Alignment
We filter this alignment to remove positions that have > 75% gaps before running GREMLIN.

[Show Jackhmmer results] - Maybe useful in deciding what regions to trim.

Δgene Ratio of paralogs Joined
A B Seq/Len
1 0.01 0.00 0.00
2 0.01 0.00 0.00
5 0.02 0.00 0.01
10 0.02 0.00 0.02
20 0.03 0.00 0.03
100 0.04 0.00 0.11
0.10 0.01 0.77
Paired alignment generation
0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Sequence A E-value:
Iterations:
Sequence B E-value:
Iterations:
Δgene MSA
Figure 1: The effect of Δgene on ratio of paralogs in the genome for each gene, and the number of sequences in the resulting joined alignment. Figure 2: Distribution of Δgene across all genomes. Figure 3: Current parameters. You can use the form to adjust the parameters and resubmit the job!

GREMLIN results (Scaled_score > 1):
Figure 4: The darker and larger the blue dots, the higher strength in coevolution.
Inter Residue pairs sorted by strength in coevolution signal:
i j Scaled Score Prob I_Prob
40_A 343_M 1.31 0.56 0.00
112_Y 282_E 1.11 0.38 0.00
62_T 398_A 1.08 0.36 0.00
45_L 189_P 1.07 0.35 0.00
108_P 172_V 1.01 0.31 0.00
61_Q 50_V 0.95 0.26 0.00
62_T 378_M 0.95 0.26 0.00
108_P 138_M 0.92 0.24 0.00
111_R 406_I 0.92 0.24 0.00
144_I 262_V 0.91 0.23 0.00
144_I 398_A 0.89 0.22 0.00
108_P 134_L 0.88 0.22 0.00
36_I 96_L 0.88 0.22 0.00
112_Y 238_K 0.88 0.21 0.00
45_L 369_L 0.88 0.21 0.00
160_I 341_L 0.88 0.21 0.00
85_L 382_A 0.87 0.21 0.00
85_L 141_G 0.86 0.21 0.00
72_F 265_A 0.86 0.21 0.00
114_I 243_P 0.86 0.20 0.00
35_D 25_I 0.86 0.20 0.00
85_L 25_I 0.84 0.19 0.00
28_F 86_D 0.84 0.19 0.00
157_L 103_L 0.84 0.19 0.00
144_I 145_M 0.83 0.19 0.00
46_H 51_L 0.83 0.19 0.00
29_L 371_A 0.83 0.19 0.00
93_T 345_L 0.83 0.19 0.00
92_L 121_Y 0.82 0.18 0.00
88_V 93_L 0.82 0.18 0.00
65_P 242_L 0.81 0.18 0.00
31_T 345_L 0.81 0.18 0.00
105_D 180_L 0.81 0.18 0.00
160_I 378_M 0.81 0.18 0.00
88_V 333_V 0.81 0.18 0.00
76_P 49_I 0.80 0.17 0.00
60_M 136_Y 0.79 0.17 0.00
Figure 5: The i (protein A) and j (protein B) are positions as given in the query sequences.

Scaled Score = raw_score/average(raw_scores)
Prob = P(contact | scaled_score, seq/len)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

ID Seq/Len Name Options I_Prob Status
3005 0.81 cI_B_6_cIII_cytb_6_Pdenitr Δgene:(1, ∞) A:(1E-06, 8) B:(1E-06, 8) msa: Jackhmmer (2015_06) 0.00 Done - Shared
2832 0.83 cI_B_cIII_cytb_Pdenitr Δgene:(1, ∞) A:(1E-04, 8) B:(1E-04, 8) msa: Jackhmmer (2015_06) 0.00 Done - Shared

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