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OPENSEQ.org

DXR - RSEP
UniProt: P45568 - P0AEH1
Length: 848
Sequences: 832
Seq/Len: 0.99
I_Prob: 0.00

DXR - 1-deoxy-D-xylulose 5-phosphate reductoisomerase
Paralog alert: 0.03 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: DXR
RSEP - Regulator of sigma E protease
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: RSEP
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
208_R 414_I 1.25 0.00
244_S 433_I 1.17 0.00
140_K 48_L 1.15 0.00
299_F 398_L 1.15 0.00
380_S 48_L 1.11 0.00
83_Q 271_S 1.06 0.00
229_G 300_G 1.05 0.00
159_S 379_Y 1.05 0.00
247_E 35_V 1.03 0.00
226_M 18_L 1.01 0.00
224_T 386_I 1.01 0.00
180_S 54_K 1.00 0.00
146_L 12_I 0.99 0.00
247_E 280_G 0.99 0.00
349_Q 158_E 0.99 0.00
79_L 257_W 0.98 0.00
111_L 416_G 0.98 0.00
226_M 70_V 0.97 0.00
225_M 352_D 0.95 0.00
191_R 98_A 0.95 0.00
140_K 224_P 0.95 0.00
17_T 42_I 0.93 0.00
290_V 416_G 0.93 0.00
101_I 105_P 0.93 0.00
382_D 70_V 0.93 0.00
220_V 28_W 0.92 0.00
381_V 42_I 0.92 0.00
49_F 417_G 0.91 0.00
77_E 48_L 0.91 0.00
284_M 145_I 0.91 0.00
233_I 447_F 0.91 0.00
105_A 330_A 0.91 0.00
50_S 154_V 0.90 0.00
178_V 421_E 0.90 0.00
239_F 416_G 0.90 0.00
225_M 367_G 0.89 0.00
85_A 19_I 0.88 0.00
272_G 18_L 0.88 0.00
239_F 35_V 0.88 0.00
380_S 407_L 0.88 0.00
279_P 300_G 0.88 0.00
118_K 112_A 0.87 0.00
2_K 246_I 0.87 0.00
270_Q 92_K 0.87 0.00
199_A 9_A 0.87 0.00
315_Y 161_D 0.87 0.00
217_K 18_L 0.87 0.00
297_L 112_A 0.86 0.00
229_G 31_R 0.86 0.00
154_N 411_I 0.86 0.00
116_A 36_R 0.86 0.00
118_K 18_L 0.85 0.00
283_T 420_S 0.84 0.00
393_V 263_L 0.84 0.00
89_A 246_I 0.84 0.00
58_D 269_G 0.83 0.00
114_I 389_N 0.83 0.00
208_R 265_R 0.83 0.00
104_A 102_A 0.83 0.00
120_I 243_G 0.82 0.00
78_V 341_T 0.82 0.00
146_L 260_F 0.82 0.00
59_E 248_K 0.82 0.00
270_Q 107_A 0.81 0.00
353_F 65_P 0.81 0.00
2_K 233_S 0.81 0.00
247_E 231_P 0.81 0.00
129_V 399_P 0.81 0.00
335_L 18_L 0.80 0.00
183_L 368_A 0.80 0.00
112_A 69_Y 0.80 0.00
205_Q 362_I 0.80 0.00
250_I 345_L 0.80 0.00
16_S 400_V 0.80 0.00
272_G 431_G 0.80 0.00
323_E 17_V 0.80 0.00
48_E 416_G 0.80 0.00
154_N 31_R 0.79 0.00
6_I 293_P 0.79 0.00
20_V 416_G 0.79 0.00
255_V 330_A 0.79 0.00
275_D 431_G 0.79 0.00
159_S 391_G 0.79 0.00
128_L 405_H 0.79 0.00
388_V 249_V 0.79 0.00
178_V 282_P 0.79 0.00
83_Q 248_K 0.79 0.00
376_D 266_D 0.78 0.00
32_A 10_S 0.78 0.00
333_T 87_H 0.78 0.00
235_A 89_F 0.78 0.00
23_H 354_K 0.78 0.00
178_V 195_L 0.78 0.00
16_S 424_Q 0.77 0.00
275_D 396_F 0.77 0.00
350_Q 110_I 0.77 0.00
89_A 288_I 0.77 0.00
154_N 56_G 0.77 0.00
283_T 59_Y 0.77 0.00
383_A 233_S 0.77 0.00
341_I 296_G 0.77 0.00
301_K 417_G 0.77 0.00
191_R 197_L 0.77 0.00
225_M 345_L 0.77 0.00
134_L 393_I 0.77 0.00
149_V 425_D 0.77 0.00
268_L 96_Q 0.77 0.00
178_V 254_L 0.76 0.00
89_A 84_L 0.76 0.00
105_A 442_A 0.76 0.00
241_A 331_T 0.76 0.00
108_L 12_I 0.76 0.00
178_V 410_A 0.76 0.00
219_S 424_Q 0.76 0.00
141_Q 274_L 0.76 0.00
259_M 93_S 0.76 0.00
341_I 324_F 0.76 0.00
246_M 435_L 0.75 0.00
130_T 53_D 0.75 0.00
394_M 230_Q 0.75 0.00
156_I 406_L 0.75 0.00
256_I 302_V 0.75 0.00
134_L 441_L 0.75 0.00
382_D 364_I 0.75 0.00
83_Q 253_P 0.75 0.00
376_D 286_T 0.74 0.00
376_D 152_K 0.74 0.00
207_C 31_R 0.74 0.00
211_N 445_N 0.74 0.00
118_K 396_F 0.74 0.00
225_M 398_L 0.74 0.00
361_L 349_I 0.74 0.00
55_V 382_F 0.73 0.00
376_D 298_A 0.73 0.00
329_Q 398_L 0.73 0.00
84_A 11_F 0.73 0.00
279_P 112_A 0.73 0.00
146_L 42_I 0.73 0.00
316_P 103_A 0.73 0.00
345_A 324_F 0.73 0.00
44_E 438_L 0.73 0.00
17_T 351_G 0.73 0.00
160_L 249_V 0.73 0.00
85_A 396_F 0.73 0.00
149_V 20_T 0.73 0.00
218_I 103_A 0.73 0.00
259_M 46_K 0.72 0.00
205_Q 272_L 0.72 0.00
277_R 19_I 0.72 0.00
27_H 256_Q 0.72 0.00
354_T 386_I 0.72 0.00
315_Y 308_V 0.72 0.00
229_G 427_C 0.72 0.00
325_F 428_Y 0.72 0.00
26_E 246_I 0.72 0.00
255_V 436_V 0.71 0.00
213_S 71_K 0.71 0.00
286_W 326_A 0.71 0.00
382_D 375_G 0.71 0.00
216_R 417_G 0.71 0.00
204_D 241_Q 0.71 0.00
310_P 409_L 0.71 0.00
246_M 96_Q 0.71 0.00
378_V 45_G 0.71 0.00
374_C 246_I 0.71 0.00
154_N 424_Q 0.71 0.00
314_R 388_V 0.71 0.00
229_G 89_F 0.71 0.00
27_H 384_A 0.71 0.00
139_V 341_T 0.71 0.00
248_V 241_Q 0.70 0.00
61_S 388_V 0.70 0.00
285_A 51_R 0.70 0.00
218_I 330_A 0.70 0.00
127_S 400_V 0.70 0.00
284_M 414_I 0.70 0.00
349_Q 433_I 0.70 0.00
324_A 411_I 0.70 0.00
130_T 75_E 0.70 0.00
48_E 296_G 0.70 0.00
327_Q 288_I 0.70 0.00
206_A 235_A 0.70 0.00
119_T 240_L 0.70 0.00
232_Y 428_Y 0.70 0.00
306_T 338_M 0.70 0.00
51_P 75_E 0.70 0.00
263_Q 115_A 0.70 0.00
197_D 264_V 0.69 0.00
118_K 420_S 0.69 0.00
225_M 450_L 0.69 0.00
236_R 96_Q 0.69 0.00
334_A 223_E 0.69 0.00
344_A 80_V 0.69 0.00
376_D 414_I 0.69 0.00
87_D 252_Q 0.69 0.00
157_F 344_M 0.69 0.00
120_I 424_Q 0.69 0.00
105_A 431_G 0.69 0.00
121_L 90_N 0.69 0.00
20_V 302_V 0.69 0.00
262_Y 424_Q 0.69 0.00
140_K 313_D 0.69 0.00
226_M 257_W 0.69 0.00
211_N 170_V 0.69 0.00
205_Q 348_L 0.68 0.00
251_H 69_Y 0.68 0.00
343_V 89_F 0.68 0.00
349_Q 287_L 0.68 0.00
20_V 383_L 0.68 0.00
179_V 269_G 0.68 0.00
256_I 320_Q 0.68 0.00
98_M 417_G 0.68 0.00
310_P 71_K 0.68 0.00
64_L 106_V 0.68 0.00
361_L 142_E 0.68 0.00
351_I 15_L 0.68 0.00
300_C 210_V 0.68 0.00
105_A 70_V 0.68 0.00
246_M 33_C 0.68 0.00
110_T 390_L 0.68 0.00
217_K 431_G 0.68 0.00
271_L 38_E 0.68 0.00
341_I 251_G 0.68 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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