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OPENSEQ.org

LEU3 - LEUC
UniProt: P30125 - P0A6A6
Length: 829
Sequences: 939
Seq/Len: 1.14
I_Prob: 0.00

LEU3 - 3-isopropylmalate dehydrogenase
Paralog alert: 0.65 [within 20: 0.02] - ratio of genomes with paralogs
Cluster includes: DMLA IDH LEU3
LEUC - 3-isopropylmalate dehydratase large subunit
Paralog alert: 0.83 [within 20: 0.04] - ratio of genomes with paralogs
Cluster includes: LEUC
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
19_V 203_F 1.18 0.00
189_K 173_K 1.16 0.00
280_Y 167_K 1.00 0.00
226_I 76_G 0.98 0.00
132_F 7_E 0.95 0.00
68_A 184_V 0.92 0.00
118_E 300_V 0.91 0.00
330_L 388_A 0.89 0.00
50_I 124_I 0.86 0.00
81_W 374_L 0.85 0.00
35_A 302_D 0.83 0.00
184_R 455_V 0.83 0.00
280_Y 404_L 0.82 0.00
35_A 269_E 0.81 0.00
15_I 95_V 0.80 0.00
273_N 445_V 0.80 0.00
350_E 394_I 0.80 0.00
254_S 424_C 0.80 0.00
135_L 208_I 0.79 0.00
308_L 168_I 0.78 0.00
335_R 440_G 0.77 0.00
21_T 210_D 0.76 0.00
19_V 59_A 0.75 0.00
128_A 211_L 0.75 0.00
168_H 339_I 0.75 0.00
73_F 367_V 0.75 0.00
188_H 190_K 0.75 0.00
95_L 90_C 0.74 0.00
347_S 238_T 0.74 0.00
73_F 226_M 0.74 0.00
325_A 168_I 0.72 0.00
87_D 18_A 0.71 0.00
214_T 370_G 0.71 0.00
176_A 255_F 0.71 0.00
86_P 124_I 0.71 0.00
66_E 244_K 0.71 0.00
341_R 363_K 0.70 0.00
214_T 173_K 0.69 0.00
67_Q 455_V 0.69 0.00
22_Q 340_D 0.69 0.00
358_Y 284_I 0.68 0.00
22_Q 352_I 0.68 0.00
57_L 139_A 0.68 0.00
60_A 282_E 0.68 0.00
248_L 412_A 0.68 0.00
50_I 60_T 0.68 0.00
220_E 176_P 0.68 0.00
132_F 295_G 0.68 0.00
221_L 245_G 0.68 0.00
93_G 369_P 0.68 0.00
215_E 299_S 0.67 0.00
175_I 363_K 0.67 0.00
322_I 275_T 0.67 0.00
215_E 243_V 0.67 0.00
25_K 269_E 0.67 0.00
218_D 339_I 0.67 0.00
100_K 320_E 0.67 0.00
149_P 191_T 0.67 0.00
161_A 301_N 0.67 0.00
19_V 438_R 0.67 0.00
8_A 213_M 0.66 0.00
248_L 157_T 0.66 0.00
348_T 355_L 0.66 0.00
220_E 269_E 0.66 0.00
176_A 124_I 0.66 0.00
52_N 388_A 0.66 0.00
19_V 232_L 0.66 0.00
19_V 235_P 0.66 0.00
348_T 438_R 0.66 0.00
135_L 60_T 0.66 0.00
19_V 150_E 0.66 0.00
307_L 248_H 0.65 0.00
190_V 375_V 0.65 0.00
190_V 388_A 0.65 0.00
173_E 361_I 0.64 0.00
293_K 207_A 0.64 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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