May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org

MEND - RHMR
UniProt: P17109 - P77732
Length: 816
Sequences: 494
Seq/Len: 0.64
I_Prob: 0.02

MEND - 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase
Paralog alert: 0.81 [within 20: 0.05] - ratio of genomes with paralogs
Cluster includes: GCL ILVB ILVG ILVI MEND OXC POXB
RHMR - Uncharacterized HTH-type transcriptional regulator RhmR
Paralog alert: 0.70 [within 20: 0.11] - ratio of genomes with paralogs
Cluster includes: ALLR ICLR KDGR MHPR RHMR YAGI YIAJ YJHI
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
50_H 214_T 1.70 0.02
241_A 117_V 1.23 0.01
466_V 68_R 1.16 0.01
221_R 217_I 1.13 0.01
434_K 88_P 0.99 0.00
254_S 183_I 0.97 0.00
386_L 42_A 0.94 0.00
497_F 114_I 0.94 0.00
383_Q 101_C 0.90 0.00
516_E 36_G 0.90 0.00
285_L 214_T 0.86 0.00
341_K 204_A 0.86 0.00
50_H 188_W 0.85 0.00
326_L 73_S 0.84 0.00
313_E 17_L 0.84 0.00
283_V 68_R 0.83 0.00
313_E 215_A 0.83 0.00
533_I 173_P 0.81 0.00
232_E 245_I 0.81 0.00
58_L 73_S 0.80 0.00
226_A 134_S 0.80 0.00
210_K 238_A 0.80 0.00
71_Q 65_L 0.80 0.00
378_D 183_I 0.79 0.00
163_G 238_A 0.79 0.00
61_L 218_S 0.79 0.00
9_R 170_I 0.78 0.00
109_P 207_F 0.78 0.00
523_D 151_A 0.77 0.00
166_I 144_L 0.77 0.00
527_T 39_K 0.76 0.00
57_G 143_C 0.76 0.00
461_P 73_S 0.76 0.00
212_R 207_F 0.75 0.00
220_K 149_P 0.75 0.00
166_I 134_S 0.75 0.00
533_I 167_P 0.75 0.00
169_P 55_L 0.75 0.00
536_V 217_I 0.75 0.00
258_Q 112_Y 0.73 0.00
334_L 40_S 0.73 0.00
301_C 141_G 0.73 0.00
512_Q 13_A 0.73 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

Page generated in 0.0831 seconds.