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OPENSEQ.org

MIAA - MUTL
UniProt: P16384 - P23367
Length: 931
Sequences: 565
Seq/Len: 0.62
I_Prob: 0.00

MIAA - tRNA dimethylallyltransferase
Paralog alert: 0.04 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: MIAA
MUTL - DNA mismatch repair protein MutL
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: MUTL
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
54_T 507_L 1.34 0.00
15_L 175_I 1.30 0.00
15_L 104_S 1.24 0.00
242_D 20_V 1.19 0.00
120_S 31_V 1.19 0.00
24_T 193_G 1.18 0.00
79_Y 13_Q 1.17 0.00
196_Q 294_I 1.15 0.00
69_L 112_S 1.12 0.00
31_R 607_P 1.12 0.00
24_T 256_C 1.11 0.00
245_S 283_D 1.11 0.00
230_V 566_M 1.11 0.00
40_S 316_R 1.10 0.00
245_S 171_I 1.10 0.00
208_E 185_V 1.09 0.00
200_F 543_I 1.06 0.00
35_P 262_M 1.05 0.00
73_R 565_L 1.05 0.00
288_G 10_L 1.04 0.00
156_A 215_I 1.04 0.00
161_H 1_M 1.03 0.00
248_C 120_A 1.02 0.00
15_L 122_Q 1.02 0.00
25_A 541_E 1.02 0.00
200_F 46_I 1.01 0.00
65_A 34_S 1.01 0.00
137_A 147_V 1.00 0.00
40_S 149_D 0.99 0.00
277_Q 68_L 0.99 0.00
69_L 166_T 0.99 0.00
252_R 13_Q 0.99 0.00
287_R 250_L 0.98 0.00
41_V 189_L 0.98 0.00
174_V 177_R 0.98 0.00
178_S 145_L 0.98 0.00
138_A 66_D 0.97 0.00
28_I 181_A 0.96 0.00
109_M 460_L 0.96 0.00
245_S 109_T 0.95 0.00
48_K 81_A 0.94 0.00
58_N 227_I 0.94 0.00
256_S 152_Y 0.94 0.00
28_I 227_I 0.93 0.00
126_D 173_E 0.93 0.00
41_V 273_R 0.93 0.00
14_F 321_F 0.93 0.00
113_K 35_L 0.93 0.00
14_F 292_L 0.93 0.00
253_Q 13_Q 0.92 0.00
51_D 54_I 0.91 0.00
72_I 104_S 0.91 0.00
92_M 263_M 0.91 0.00
38_L 196_V 0.91 0.00
48_K 478_P 0.91 0.00
95_I 63_I 0.91 0.00
85_R 234_L 0.91 0.00
114_A 7_P 0.91 0.00
243_L 583_D 0.90 0.00
100_R 66_D 0.90 0.00
305_D 610_K 0.90 0.00
257_Y 101_S 0.90 0.00
50_M 49_G 0.90 0.00
230_V 275_A 0.89 0.00
163_N 101_S 0.89 0.00
308_L 612_L 0.89 0.00
264_Y 537_I 0.89 0.00
66_P 191_H 0.89 0.00
44_A 112_S 0.89 0.00
286_L 460_L 0.88 0.00
80_S 254_Q 0.88 0.00
43_S 86_L 0.88 0.00
123_P 211_R 0.88 0.00
308_L 608_A 0.88 0.00
13_I 318_V 0.88 0.00
270_R 106_S 0.88 0.00
175_F 24_A 0.87 0.00
252_R 265_D 0.87 0.00
130_R 127_G 0.87 0.00
104_L 161_L 0.86 0.00
274_A 136_P 0.86 0.00
223_A 293_E 0.86 0.00
15_L 477_A 0.86 0.00
238_D 251_A 0.86 0.00
176_F 215_I 0.86 0.00
259_E 569_H 0.86 0.00
278_L 83_L 0.86 0.00
245_S 264_R 0.86 0.00
302_Q 394_Q 0.86 0.00
160_I 103_S 0.85 0.00
213_R 80_I 0.85 0.00
174_V 270_H 0.85 0.00
133_I 216_C 0.85 0.00
127_P 236_L 0.85 0.00
61_E 34_S 0.85 0.00
79_Y 138_A 0.85 0.00
85_R 255_Y 0.85 0.00
38_L 212_L 0.85 0.00
83_D 514_F 0.84 0.00
196_Q 505_S 0.84 0.00
175_F 181_A 0.84 0.00
196_Q 446_C 0.84 0.00
114_A 546_L 0.84 0.00
230_V 100_A 0.84 0.00
166_Q 211_R 0.84 0.00
289_W 100_A 0.84 0.00
13_I 294_I 0.84 0.00
245_S 583_D 0.84 0.00
80_S 136_P 0.84 0.00
80_S 164_E 0.83 0.00
132_R 440_T 0.83 0.00
275_T 234_L 0.83 0.00
94_D 7_P 0.83 0.00
116_L 175_I 0.83 0.00
187_Q 40_T 0.83 0.00
26_L 12_N 0.83 0.00
148_Q 525_A 0.83 0.00
150_Q 31_V 0.83 0.00
269_Y 162_R 0.83 0.00
265_D 385_R 0.83 0.00
50_M 192_N 0.83 0.00
27_A 215_I 0.83 0.00
178_S 198_Q 0.83 0.00
13_I 293_E 0.83 0.00
134_E 263_M 0.82 0.00
84_F 294_I 0.82 0.00
134_E 292_L 0.82 0.00
118_G 211_R 0.82 0.00
115_L 144_T 0.82 0.00
129_V 541_E 0.82 0.00
83_D 332_Q 0.82 0.00
154_P 290_L 0.82 0.00
302_Q 607_P 0.82 0.00
57_P 258_V 0.82 0.00
276_R 46_I 0.82 0.00
48_K 582_A 0.81 0.00
113_K 113_R 0.81 0.00
41_V 112_S 0.81 0.00
128_E 152_Y 0.81 0.00
168_L 26_V 0.81 0.00
39_I 520_H 0.81 0.00
138_A 580_L 0.81 0.00
264_Y 215_I 0.81 0.00
289_W 308_H 0.81 0.00
302_Q 610_K 0.81 0.00
101_I 448_L 0.81 0.00
113_K 194_K 0.81 0.00
74_D 471_Q 0.81 0.00
301_E 394_Q 0.81 0.00
30_L 272_I 0.81 0.00
278_L 13_Q 0.81 0.00
247_R 211_R 0.80 0.00
110_L 319_H 0.80 0.00
62_L 57_R 0.80 0.00
175_F 82_S 0.80 0.00
144_S 580_L 0.80 0.00
228_A 289_V 0.80 0.00
38_L 517_D 0.80 0.00
301_E 607_P 0.80 0.00
48_K 410_Q 0.80 0.00
202_I 135_K 0.80 0.00
28_I 55_R 0.80 0.00
16_M 192_N 0.80 0.00
226_F 24_A 0.80 0.00
79_Y 275_A 0.80 0.00
113_K 303_V 0.80 0.00
156_A 227_I 0.80 0.00
265_D 505_S 0.80 0.00
278_L 469_Q 0.80 0.00
294_W 92_L 0.80 0.00
283_I 323_Y 0.80 0.00
249_V 595_P 0.80 0.00
113_K 270_H 0.80 0.00
61_E 59_N 0.79 0.00
60_E 413_A 0.79 0.00
97_A 508_A 0.79 0.00
50_M 108_L 0.79 0.00
291_G 488_L 0.79 0.00
174_V 319_H 0.79 0.00
15_L 294_I 0.79 0.00
48_K 379_A 0.79 0.00
115_L 530_L 0.79 0.00
249_V 13_Q 0.79 0.00
161_H 446_C 0.78 0.00
33_I 81_A 0.78 0.00
101_I 20_V 0.78 0.00
109_M 445_D 0.78 0.00
104_L 276_C 0.78 0.00
241_T 82_S 0.78 0.00
228_A 346_P 0.78 0.00
227_E 447_A 0.78 0.00
39_I 169_N 0.78 0.00
129_V 100_A 0.78 0.00
48_K 374_P 0.78 0.00
183_T 103_S 0.78 0.00
260_G 92_L 0.78 0.00
110_L 100_A 0.78 0.00
146_H 412_P 0.77 0.00
92_M 27_V 0.77 0.00
61_E 156_A 0.77 0.00
230_V 523_I 0.77 0.00
178_S 291_Y 0.77 0.00
110_L 447_A 0.77 0.00
92_M 214_A 0.77 0.00
289_W 128_R 0.77 0.00
257_Y 186_T 0.77 0.00
171_A 86_L 0.77 0.00
294_W 1_M 0.77 0.00
185_L 225_L 0.77 0.00
178_S 526_V 0.77 0.00
84_F 270_H 0.77 0.00
247_R 314_Q 0.77 0.00
13_I 257_Y 0.77 0.00
163_N 54_I 0.77 0.00
51_D 159_K 0.77 0.00
66_P 271_A 0.77 0.00
118_G 319_H 0.76 0.00
146_H 59_N 0.76 0.00
271_G 593_K 0.76 0.00
244_P 265_D 0.76 0.00
283_I 240_V 0.76 0.00
283_I 188_N 0.76 0.00
35_P 171_I 0.76 0.00
126_D 542_L 0.76 0.00
166_Q 281_G 0.76 0.00
246_I 56_I 0.76 0.00
205_A 151_F 0.76 0.00
278_L 270_H 0.76 0.00
48_K 4_Q 0.76 0.00
237_G 249_A 0.76 0.00
113_K 531_R 0.76 0.00
215_E 606_H 0.76 0.00
268_V 519_Q 0.76 0.00
79_Y 130_M 0.76 0.00
113_K 185_V 0.76 0.00
306_E 394_Q 0.75 0.00
204_P 585_E 0.75 0.00
187_Q 81_A 0.75 0.00
39_I 38_G 0.75 0.00
194_P 170_H 0.75 0.00
262_I 215_I 0.75 0.00
38_L 478_P 0.75 0.00
78_A 120_A 0.75 0.00
200_F 481_A 0.75 0.00
242_D 294_I 0.75 0.00
212_Q 502_K 0.75 0.00
46_I 241_A 0.75 0.00
175_F 31_V 0.75 0.00
58_N 34_S 0.75 0.00
32_K 40_T 0.75 0.00
226_F 447_A 0.75 0.00
278_L 112_S 0.75 0.00
200_F 519_Q 0.75 0.00
47_Y 151_F 0.75 0.00
174_V 254_Q 0.75 0.00
293_H 228_E 0.75 0.00
28_I 39_A 0.75 0.00
44_A 273_R 0.75 0.00
237_G 2_P 0.75 0.00
119_L 257_Y 0.75 0.00
90_A 609_I 0.75 0.00
295_L 320_D 0.75 0.00
235_A 84_D 0.75 0.00
196_Q 299_V 0.75 0.00
295_L 149_D 0.75 0.00
228_A 500_L 0.74 0.00
271_G 216_C 0.74 0.00
288_G 591_L 0.74 0.00
46_I 486_I 0.74 0.00
26_L 34_S 0.74 0.00
175_F 541_E 0.74 0.00
46_I 5_V 0.74 0.00
283_I 442_V 0.74 0.00
301_E 395_P 0.74 0.00
291_G 163_T 0.74 0.00
263_S 91_S 0.74 0.00
151_E 422_E 0.74 0.00
81_A 137_A 0.74 0.00
235_A 543_I 0.74 0.00
246_I 49_G 0.74 0.00
82_A 583_D 0.74 0.00
54_T 403_E 0.74 0.00
195_Y 40_T 0.74 0.00
131_A 400_Q 0.74 0.00
85_R 170_H 0.74 0.00
138_A 228_E 0.73 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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