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OPENSEQ.org

BIOA - BIOF
UniProt: P12995 - P12998
Length: 813
Sequences: 746
Seq/Len: 0.94
I_Prob: 0.00

BIOA - Adenosylmethionine-8-amino-7-oxononanoate aminotransferase
Paralog alert: 0.89 [within 20: 0.11] - ratio of genomes with paralogs
Cluster includes: ARGD ASTC BIOA GABT GSA PAT PUUE
BIOF - 8-amino-7-oxononanoate synthase
Paralog alert: 0.62 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: BIOF KBL
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
1wyuAEGC:BHDF:BHDF:AEGCContact Map


Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
247_I 362_L 1.12 0.00
134_R 279_S 1.09 0.00
368_V 154_D 0.98 0.00
394_G 235_G 0.97 0.00
235_C 318_S 0.91 0.00
137_F 142_L 0.85 0.00
285_A 126_I 0.85 0.00
397_I 232_V 0.84 0.00
195_A 362_L 0.83 0.00
286_T 124_D 0.82 0.00
72_I 332_L 0.81 0.00
105_C 104_L 0.80 0.00
289_T 224_K 0.79 0.00
334_Q 330_R 0.78 0.00
120_M 86_H 0.77 0.00
288_T 253_D 0.77 0.00
421_V 158_L 0.77 0.00
409_Q 324_I 0.77 0.00
291_E 334_L 0.77 0.00
83_I 265_S 0.77 0.00
31_S 363_T 0.76 0.00
165_W 318_S 0.76 0.00
65_N 173_V 0.76 0.00
324_L 56_P 0.76 0.00
138_L 190_I 0.75 0.00
138_L 102_A 0.75 0.00
324_L 267_S 0.75 0.00
318_A 153_N 0.75 0.00
200_A 114_A 0.74 0.00
248_A 137_L 0.74 0.00
292_V 126_I 0.74 0.00
87_P 255_L 0.74 0.00
205_I 355_A 0.73 0.00
214_V 181_D 0.73 0.00
98_M 300_T 0.73 0.00
309_T 346_T 0.73 0.00
261_E 265_S 0.72 0.00
210_I 115_V 0.72 0.00
115_A 344_W 0.72 0.00
301_A 114_A 0.72 0.00
383_F 45_S 0.71 0.00
365_I 181_D 0.71 0.00
347_L 326_G 0.71 0.00
44_R 294_K 0.71 0.00
150_G 75_G 0.70 0.00
321_N 151_A 0.70 0.00
124_L 232_V 0.70 0.00
227_W 299_I 0.70 0.00
139_T 259_A 0.70 0.00
410_L 380_L 0.70 0.00
392_P 48_D 0.69 0.00
134_R 138_E 0.69 0.00
161_M 53_S 0.69 0.00
409_Q 184_S 0.69 0.00
354_E 356_G 0.69 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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