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OPENSEQ.org

BIOA - BIOB
UniProt: P12995 - P12996
Length: 775
Sequences: 579
Seq/Len: 0.78
I_Prob: 0.00

BIOA - Adenosylmethionine-8-amino-7-oxononanoate aminotransferase
Paralog alert: 0.89 [within 20: 0.11] - ratio of genomes with paralogs
Cluster includes: ARGD ASTC BIOA GABT GSA PAT PUUE
BIOB - Biotin synthase
Paralog alert: 0.58 [within 20: 0.14] - ratio of genomes with paralogs
Cluster includes: BIOB THIH
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
115_A 111_P 1.43 0.00
204_E 40_V 1.23 0.00
207_A 210_A 1.09 0.00
98_M 211_N 1.09 0.00
281_M 228_K 0.99 0.00
292_V 71_E 0.97 0.00
319_A 172_E 0.93 0.00
37_L 46_L 0.91 0.00
197_L 247_I 0.91 0.00
213_I 189_S 0.90 0.00
115_A 156_T 0.89 0.00
286_T 281_A 0.88 0.00
287_L 154_L 0.87 0.00
385_E 8_T 0.86 0.00
96_V 245_R 0.86 0.00
70_S 117_V 0.85 0.00
106_V 40_V 0.85 0.00
115_A 257_S 0.84 0.00
264_E 175_D 0.84 0.00
93_R 30_V 0.84 0.00
270_L 134_L 0.83 0.00
319_A 245_R 0.82 0.00
312_G 54_P 0.82 0.00
404_I 125_L 0.81 0.00
284_S 166_T 0.80 0.00
42_G 15_L 0.78 0.00
96_V 11_Q 0.78 0.00
406_L 8_T 0.78 0.00
134_R 96_F 0.78 0.00
265_I 140_Q 0.78 0.00
239_G 306_R 0.78 0.00
233_K 10_S 0.77 0.00
41_D 90_A 0.76 0.00
421_V 30_V 0.76 0.00
176_P 117_V 0.76 0.00
214_V 76_M 0.76 0.00
105_C 245_R 0.75 0.00
130_K 195_L 0.75 0.00
90_E 81_V 0.74 0.00
322_A 259_V 0.74 0.00
105_C 235_N 0.74 0.00
207_A 187_V 0.74 0.00
310_F 240_A 0.74 0.00
288_T 186_K 0.74 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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