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OPENSEQ.org

EFG - EFTU1
UniProt: P0A6M8 - P0CE47
Length: 1098
Sequences: 689
Seq/Len: 0.63
I_Prob: 0.08

EFG - Elongation factor G
Paralog alert: 0.37 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: EFG LEPA RF3 TYPA
EFTU1 - Elongation factor Tu 1
Paralog alert: 0.35 [within 20: 0.04] - ratio of genomes with paralogs
Cluster includes: CYSN EFTU1 EFTU2
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
3r7wAC:BD:AC:BDContact Map
2qagB:A:A:B:CContact Map


Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
642_L 259_V 1.82 0.08
669_Q 220_S 1.55 0.04
440_K 222_S 1.50 0.04
332_N 222_S 1.46 0.03
505_H 107_A 1.27 0.02
193_W 228_V 1.21 0.01
431_M 206_A 1.17 0.01
45_D 367_I 1.16 0.01
444_S 222_S 1.16 0.01
507_K 107_A 1.16 0.01
674_T 269_G 1.14 0.01
363_I 287_I 1.10 0.01
347_D 209_K 1.08 0.01
263_L 273_E 1.07 0.01
97_I 269_G 1.07 0.01
641_M 241_E 1.06 0.01
270_F 308_E 1.06 0.01
146_R 283_K 1.03 0.01
360_F 298_T 1.03 0.01
444_S 228_V 1.01 0.01
654_I 326_G 0.99 0.01
350_L 256_C 0.99 0.01
269_A 285_E 0.99 0.01
160_T 15_V 0.98 0.01
97_I 222_S 0.96 0.01
420_V 89_V 0.96 0.01
509_S 123_G 0.95 0.01
498_V 9_T 0.95 0.01
183_V 159_S 0.95 0.01
32_F 222_S 0.95 0.01
507_K 154_V 0.95 0.01
200_V 222_S 0.94 0.01
1_M 40_Y 0.94 0.01
256_V 248_I 0.94 0.01
139_A 171_V 0.93 0.01
334_T 287_I 0.93 0.01
375_K 64_N 0.93 0.01
444_S 309_V 0.93 0.01
334_T 182_D 0.93 0.01
182_V 107_A 0.93 0.01
635_L 170_I 0.92 0.01
383_A 57_K 0.92 0.01
609_K 52_N 0.92 0.01
447_V 47_F 0.91 0.01
335_F 66_S 0.91 0.01
512_R 232_V 0.91 0.01
700_E 4_E 0.91 0.01
244_T 48_D 0.91 0.01
435_L 273_E 0.90 0.01
509_S 367_I 0.90 0.01
450_D 386_A 0.90 0.01
282_V 167_D 0.90 0.01
654_I 37_A 0.90 0.01
616_I 171_V 0.90 0.01
191_I 131_I 0.90 0.01
348_T 21_V 0.89 0.01
286_L 58_A 0.89 0.01
612_L 286_E 0.89 0.01
342_V 315_D 0.89 0.01
32_F 362_T 0.89 0.01
154_V 135_L 0.88 0.01
45_D 215_I 0.88 0.01
478_N 196_L 0.88 0.01
409_M 269_G 0.88 0.01
459_A 107_A 0.88 0.01
674_T 58_A 0.88 0.01
437_R 58_A 0.87 0.00
335_F 65_T 0.87 0.00
678_A 308_E 0.87 0.00
203_E 284_R 0.87 0.00
45_D 147_L 0.87 0.00
132_K 373_L 0.86 0.00
674_T 232_V 0.86 0.00
332_N 361_V 0.86 0.00
239_G 57_K 0.86 0.00
350_L 15_V 0.86 0.00
453_S 287_I 0.86 0.00
507_K 109_T 0.86 0.00
661_S 170_I 0.86 0.00
585_D 286_E 0.85 0.00
282_V 275_V 0.85 0.00
489_A 74_T 0.85 0.00
641_M 222_S 0.85 0.00
467_D 107_A 0.84 0.00
505_H 109_T 0.84 0.00
222_L 284_R 0.84 0.00
1_M 222_S 0.84 0.00
431_M 284_R 0.84 0.00
286_L 268_E 0.84 0.00
315_E 393_L 0.84 0.00
578_L 156_E 0.83 0.00
538_N 393_L 0.83 0.00
223_I 286_E 0.83 0.00
347_D 228_V 0.83 0.00
473_M 232_V 0.83 0.00
646_E 107_A 0.83 0.00
697_A 144_E 0.83 0.00
444_S 283_K 0.83 0.00
226_A 196_L 0.83 0.00
685_L 370_D 0.83 0.00
332_N 64_N 0.83 0.00
302_G 41_G 0.82 0.00
150_N 206_A 0.82 0.00
116_V 64_N 0.82 0.00
642_L 254_S 0.82 0.00
667_A 177_K 0.82 0.00
500_D 66_S 0.82 0.00
217_E 66_S 0.82 0.00
357_R 49_Q 0.82 0.00
199_G 376_A 0.81 0.00
247_E 200_I 0.81 0.00
49_T 198_S 0.81 0.00
509_S 71_D 0.81 0.00
674_T 243_V 0.81 0.00
478_N 193_A 0.81 0.00
277_A 57_K 0.81 0.00
103_M 64_N 0.80 0.00
255_R 187_A 0.80 0.00
604_G 107_A 0.80 0.00
5_T 282_I 0.80 0.00
404_I 135_L 0.80 0.00
604_G 21_V 0.80 0.00
420_V 228_V 0.79 0.00
444_S 269_G 0.79 0.00
350_L 392_V 0.79 0.00
218_W 21_V 0.79 0.00
140_F 300_K 0.79 0.00
362_R 240_G 0.79 0.00
372_E 64_N 0.79 0.00
515_Y 37_A 0.79 0.00
202_F 222_S 0.78 0.00
440_K 342_I 0.78 0.00
259_N 359_M 0.78 0.00
321_A 21_V 0.78 0.00
294_A 21_V 0.78 0.00
431_M 259_V 0.78 0.00
38_H 65_T 0.78 0.00
311_A 43_A 0.78 0.00
347_D 215_I 0.78 0.00
270_F 251_T 0.77 0.00
502_E 284_R 0.77 0.00
678_A 47_F 0.77 0.00
200_V 287_I 0.77 0.00
697_A 64_N 0.77 0.00
193_W 287_I 0.77 0.00
84_I 341_T 0.77 0.00
481_A 258_G 0.77 0.00
37_N 283_K 0.77 0.00
538_N 243_V 0.77 0.00
654_I 382_R 0.77 0.00
113_Y 58_A 0.77 0.00
225_S 171_V 0.77 0.00
197_D 156_E 0.77 0.00
473_M 134_F 0.77 0.00
357_R 389_V 0.76 0.00
365_Q 89_V 0.76 0.00
386_I 273_E 0.76 0.00
193_W 220_S 0.76 0.00
437_R 284_R 0.76 0.00
377_V 21_V 0.76 0.00
597_A 369_M 0.76 0.00
97_I 220_S 0.76 0.00
697_A 170_I 0.76 0.00
175_A 182_D 0.76 0.00
113_Y 47_F 0.76 0.00
579_H 57_K 0.76 0.00
375_K 251_T 0.76 0.00
656_A 154_V 0.76 0.00
573_D 299_I 0.75 0.00
363_I 269_G 0.75 0.00
648_E 210_P 0.75 0.00
451_E 138_C 0.75 0.00
432_G 215_I 0.75 0.00
112_V 291_Q 0.75 0.00
138_I 171_V 0.75 0.00
383_A 241_E 0.75 0.00
243_L 255_T 0.75 0.00
226_A 89_V 0.75 0.00
234_M 144_E 0.75 0.00
467_D 315_D 0.75 0.00
377_V 57_K 0.75 0.00
503_G 386_A 0.75 0.00
420_V 188_K 0.75 0.00
363_I 228_V 0.74 0.00
651_G 4_E 0.74 0.00
209_A 58_A 0.74 0.00
623_T 42_G 0.74 0.00
182_V 367_I 0.74 0.00
445_F 371_D 0.74 0.00
131_N 376_A 0.74 0.00
403_P 41_G 0.74 0.00
483_V 73_P 0.74 0.00
557_I 250_E 0.74 0.00
612_L 326_G 0.74 0.00
391_V 392_V 0.74 0.00
467_D 189_I 0.74 0.00
16_S 147_L 0.74 0.00
618_K 89_V 0.74 0.00
139_A 162_D 0.74 0.00
674_T 160_Q 0.74 0.00
40_I 348_V 0.73 0.00
157_Q 89_V 0.73 0.00
483_V 148_E 0.73 0.00
696_Q 202_E 0.73 0.00
7_I 42_G 0.73 0.00
288_S 242_E 0.73 0.00
209_A 4_E 0.73 0.00
114_C 58_A 0.73 0.00
288_S 241_E 0.73 0.00
82_H 159_S 0.73 0.00
262_I 374_R 0.73 0.00
175_A 181_G 0.73 0.00
377_V 367_I 0.73 0.00
158_I 215_I 0.73 0.00
518_V 275_V 0.73 0.00
603_E 73_P 0.73 0.00
689_E 254_S 0.73 0.00
563_A 171_V 0.72 0.00
583_Y 214_P 0.72 0.00
116_V 376_A 0.72 0.00
261_I 326_G 0.72 0.00
233_L 287_I 0.72 0.00
573_D 258_G 0.72 0.00
657_E 107_A 0.72 0.00
667_A 348_V 0.72 0.00
348_T 228_V 0.72 0.00
97_I 47_F 0.72 0.00
692_S 220_S 0.72 0.00
469_I 37_A 0.72 0.00
278_M 166_D 0.72 0.00
255_R 135_L 0.72 0.00
470_V 5_K 0.72 0.00
678_A 369_M 0.72 0.00
265_T 286_E 0.72 0.00
347_D 222_S 0.71 0.00
552_A 326_G 0.71 0.00
646_E 284_R 0.71 0.00
182_V 109_T 0.71 0.00
444_S 287_I 0.71 0.00
494_I 37_A 0.71 0.00
157_Q 181_G 0.71 0.00
223_I 66_S 0.71 0.00
71_F 250_E 0.71 0.00
217_E 170_I 0.71 0.00
117_G 325_K 0.71 0.00
236_K 21_V 0.71 0.00
353_V 64_N 0.71 0.00
347_D 256_C 0.71 0.00
45_D 283_K 0.71 0.00
255_R 309_V 0.71 0.00
243_L 13_V 0.71 0.00
502_E 255_T 0.71 0.00
551_P 287_I 0.71 0.00
254_Q 162_D 0.70 0.00
193_W 282_I 0.70 0.00
391_V 193_A 0.70 0.00
270_F 182_D 0.70 0.00
202_F 40_Y 0.70 0.00
202_F 41_G 0.70 0.00
134_K 57_K 0.70 0.00
678_A 269_G 0.70 0.00
444_S 220_S 0.70 0.00
557_I 71_D 0.70 0.00
226_A 256_C 0.70 0.00
622_E 72_T 0.70 0.00
364_V 273_E 0.70 0.00
642_L 308_E 0.70 0.00
654_I 232_V 0.70 0.00
563_A 58_A 0.70 0.00
589_S 361_V 0.69 0.00
188_M 297_G 0.69 0.00
2_A 162_D 0.69 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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