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OPENSEQ.org

ILVI - LEU3
UniProt: P00893 - P30125
Length: 937
Sequences: 587
Seq/Len: 0.64
I_Prob: 0.00

ILVI - Acetolactate synthase isozyme 3 large subunit
Paralog alert: 0.81 [within 20: 0.05] - ratio of genomes with paralogs
Cluster includes: GCL ILVB ILVG ILVI MEND OXC POXB
LEU3 - 3-isopropylmalate dehydrogenase
Paralog alert: 0.65 [within 20: 0.02] - ratio of genomes with paralogs
Cluster includes: DMLA IDH LEU3
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
472_N 190_V 1.40 0.00
96_L 359_V 1.27 0.00
425_F 268_P 1.12 0.00
99_L 66_E 1.10 0.00
383_R 294_N 1.10 0.00
358_R 144_I 1.06 0.00
46_V 19_V 1.02 0.00
468_V 295_I 1.01 0.00
196_I 294_N 0.98 0.00
235_L 234_I 0.97 0.00
279_V 105_F 0.93 0.00
307_P 123_L 0.92 0.00
515_G 307_L 0.91 0.00
470_V 283_A 0.91 0.00
230_V 308_L 0.91 0.00
96_L 276_G 0.90 0.00
439_E 29_A 0.90 0.00
301_L 276_G 0.89 0.00
522_H 211_E 0.89 0.00
125_V 280_Y 0.89 0.00
239_C 98_L 0.88 0.00
381_L 315_A 0.88 0.00
7_A 10_L 0.85 0.00
324_A 300_A 0.85 0.00
468_V 101_H 0.85 0.00
96_L 301_Q 0.84 0.00
159_V 191_T 0.84 0.00
183_R 19_V 0.84 0.00
301_L 168_H 0.84 0.00
71_V 301_Q 0.84 0.00
378_I 62_V 0.83 0.00
206_A 173_E 0.83 0.00
507_L 175_I 0.83 0.00
542_F 212_I 0.83 0.00
507_L 294_N 0.82 0.00
162_P 98_L 0.82 0.00
468_V 216_Y 0.82 0.00
144_K 176_A 0.82 0.00
148_L 193_I 0.82 0.00
390_Y 125_A 0.80 0.00
389_A 175_I 0.80 0.00
319_P 300_A 0.80 0.00
196_I 181_E 0.79 0.00
29_A 225_Y 0.79 0.00
496_S 20_M 0.79 0.00
517_Q 212_I 0.79 0.00
10_V 264_M 0.79 0.00
439_E 211_E 0.79 0.00
254_A 136_C 0.79 0.00
279_V 208_I 0.78 0.00
301_L 355_I 0.78 0.00
248_P 59_P 0.77 0.00
273_A 212_I 0.77 0.00
394_D 202_S 0.77 0.00
523_E 213_A 0.77 0.00
354_I 313_L 0.76 0.00
46_V 64_G 0.76 0.00
301_L 272_L 0.76 0.00
562_G 58_P 0.76 0.00
325_R 313_L 0.76 0.00
231_E 189_K 0.76 0.00
244_L 144_I 0.75 0.00
86_I 278_G 0.75 0.00
129_S 68_A 0.75 0.00
36_A 333_G 0.75 0.00
445_V 355_I 0.75 0.00
54_A 17_P 0.75 0.00
231_E 59_P 0.75 0.00
354_I 71_V 0.75 0.00
531_A 212_I 0.74 0.00
22_V 270_A 0.74 0.00
162_P 336_T 0.74 0.00
514_V 7_I 0.74 0.00
492_R 322_I 0.74 0.00
472_N 60_A 0.74 0.00
85_G 307_L 0.74 0.00
159_V 22_Q 0.74 0.00
522_H 9_V 0.74 0.00
300_V 321_A 0.73 0.00
46_V 39_T 0.73 0.00
82_A 264_M 0.73 0.00
208_K 97_P 0.73 0.00
94_I 319_A 0.73 0.00
206_A 20_M 0.73 0.00
211_V 212_I 0.73 0.00
467_P 264_M 0.73 0.00
137_D 168_H 0.73 0.00
277_F 295_I 0.73 0.00
46_V 191_T 0.72 0.00
235_L 20_M 0.72 0.00
203_L 37_R 0.72 0.00
443_V 184_R 0.72 0.00
293_K 293_K 0.72 0.00
83_I 172_I 0.72 0.00
434_K 190_V 0.72 0.00
206_A 356_A 0.72 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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