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Instructions
  • Use the menu to the right to browse the coupling matrix, or select a position from the PSSM below to see what it is coupled with.
Conservation matrix (aka PSSM)
- A F I L V M W Y D E K R H N Q S T G P C
0002 0.3 -1 -0.9 0.1 0.2 -0.6 -1.9 -0.9 -0.6 0.3 1 0.3 -1.2 0 0.5 0.2 -0.3 2.4 -0.1 -1.7
0003 0.1 -0.8 0.3 0.5 0.6 -0.4 -1.3 -1 -0.6 -0.4 0.3 0.3 -0.6 -0.1 0.2 0.4 0.2 0.2 0.8 -0.4
0004 -0.1 -0.2 0.6 0.9 1 0.1 -0.6 0.1 -0.8 0.1 0.7 0.5 -0.1 -0.7 0.2 -0.2 1.3 -1.3 0.1 -0.5
0005 2.5 0.9 0.1 0.9 2.5 0.7 -1.1 1 -1 -0.9 -0.8 -0.6 -1.1 -1.6 -1.2 0 -0.3 -0.2 -1 1.4
0006 -0.6 0.1 1.1 0.7 1.6 -0.3 -0.9 0.2 -1.2 0 0.8 1 -0.8 -1.2 1 -0.3 0.8 -0.5 -1 -1
0007 2 -0.7 -0.2 0.4 1.3 -0.4 -1.1 -0.8 -0.9 -0.8 -0.7 -0.4 -0.2 -1.1 -0.6 2 1 0.8 -0.4 0.9
0008 0.4 -1 1.9 2.7 2 0.8 -1.2 -1.8 -1.1 -0.5 0.5 0.4 -1.2 -0.1 0.7 0.2 1 -1.4 -1.3 -0.7
0009 0.4 0.8 -0.7 0.2 -0.2 -0.4 0.3 1.4 -0.3 0.1 0.3 0.6 0.3 -0.4 -0.2 0.1 0 -0.6 -1.1 0
0010 1.3 -1.4 -0.6 -0.9 -0.7 -1.4 -1.6 -1 2.5 1.2 0.1 -0.2 -0.2 1 0.4 1.3 0.4 0.6 1.3 -1.3
0011 -0.1 1.6 -0.2 0.9 -0.2 -0.7 0.3 2.2 -0.5 -0.7 -0.4 -0.3 0.8 -0.2 -0.4 0.5 -0.5 -0.4 -0.8 -0.3
0012 0.4 -1.3 -0.6 0 0.6 -0.9 -2 -1.6 0.9 1.6 0.8 0.6 -0.4 1 0.8 0.9 1 -0.5 0.1 -0.9
0013 1.1 -0.7 -0.1 0.1 0.1 -1.2 -1.1 -0.6 -0.2 -0.2 0.1 -0.2 -0.7 -0.6 -0.5 1.8 0.6 1.1 1.4 -0.4
0014 0 -1.1 -0.9 0.1 -0.3 -0.5 -1.5 -1.4 1.3 1.4 0.4 0.9 -0.3 0.8 1.2 0.9 0.8 0.1 -0.4 -1.4
0015 0.5 -1.4 -0.8 -0.2 -0.7 -1 -1.9 -1.6 1.9 1.8 -0.3 0.1 0.3 1.5 0.3 1.4 0.7 0.6 -0.4 -1.1
0016 1.6 -1.6 -1 -0.5 -0.3 -1.8 -1.9 -1.6 2.2 2.5 0.4 -0.2 -0.6 0.7 0.5 1.6 0.4 0.2 2.3 -1.9
0017 0.2 -1.5 -0.7 -0.7 -0.3 -0.8 -1.7 -0.8 2 1.3 -0.2 0.1 0.1 1.6 0.3 1.4 1.1 1.6 -0.9 -0.8
0018 -0.2 -0.3 -0.1 0.1 -0.8 -0.7 -0.9 0.1 1.6 2.2 0.6 -0.5 0 -0.5 0.5 -0.1 -0.1 0.3 -0.4 -0.2
0019 0.7 0.9 1 3.7 0.8 1.4 -0.6 -0.8 -1.1 -1.1 -0.9 -0.6 0.2 -0.6 -1.1 0 -0.3 -0.7 -0.1 -0.2
0020 1 -0.7 -0.7 -0.9 -0.1 -1.2 -1.7 -1.1 0.7 0.6 0.1 -0.1 -0.4 0.7 0.2 2.1 1.4 0.6 0.8 -0.4
0021 -0.1 1.9 0.3 1.9 0.9 0.8 -0.7 -0.4 -0.9 -0.7 -0.5 -0.5 -0.7 -0.9 -0.3 0.4 0 -0.5 -0.4 0.4
0022 0.4 -0.7 -0.6 -0.1 0.4 -0.8 -1.5 -0.5 0.3 1.2 0.4 0.6 -0.3 0.8 0.8 0.9 0.7 -0.2 -0.4 -0.8
0023 1.6 -1.4 0.3 -0.2 1.3 -0.6 -1.8 -1.4 -0.4 2.2 2.5 1.3 -1.2 -1.1 0.9 0.1 0.3 -1.4 1.1 -0.9
0024 0.3 -1 -1.5 -1.4 -0.9 -1.3 -1.1 -0.4 2.3 0.4 -0.3 0 0.5 2.8 -0.6 0.9 -0.5 5 -1.1 -1.2
0025 0.7 -1 -0.3 -0.1 0.1 -0.1 -1.1 -0.8 2.2 2.1 -0.8 -0.2 -0.2 0 0.6 0.8 0.8 0 -1.3 -0.6
0026 -0.1 -0.5 1.8 1.5 2 0.2 -1.8 -0.4 -1.3 0.7 1 0.9 -0.2 -0.9 0.4 -0.4 1 -1.5 -0.7 -0.5
0027 -0.3 0.6 1.4 1.8 2.1 0.4 -0.3 0.4 -0.3 -0.6 -0.7 -0.4 -0.7 -0.6 -0.2 0.1 -0.3 -0.3 -0.7 -0.7
0028 -0.1 -0.4 0.7 0.9 1.2 -0.8 -0.9 0.4 0.4 1.4 0.3 0.8 -0.1 -0.4 0.6 0.1 1.6 -1.2 -1.7 -0.9
0029 0.4 0.2 2.1 2 3 -0.2 -1.1 -0.7 -0.8 -0.3 -1 -0.7 -0.4 0.3 -0.5 -0.2 -0.1 -0.4 -0.8 -0.4
0030 -0.1 -0.3 2.4 2 2.2 -0.3 -1.1 -0.1 -0.7 -0.6 -0.5 -0.6 0.4 -0.6 -0.6 0.4 0.8 -0.3 -1.1 -0.1
0031 0.4 -1.5 -0.9 -0.5 -0.6 -1.7 -1.6 -0.8 1.4 1.6 1.3 1 -0.3 0.6 0.7 1.5 0.7 0.8 -0.6 -1.1
- A F I L V M W Y D E K R H N Q S T G P C
0032 0.1 -0.9 0.2 -0.4 0.2 -0.5 -1.2 -0.8 1 1.2 1.4 1 -0.3 0.2 0.6 0.3 0.2 -0.6 -0.1 -1.1
0033 0.3 -0.4 0.7 0.5 0.5 -0.4 -1.9 -0.9 1.3 0.9 -0.4 -0.1 -0.2 -0.1 -0.1 0.1 0.6 0.3 0.4 -0.8
0034 0.1 -1 -1.2 -0.4 -0.5 -1.3 -1.9 -0.8 2.9 1.9 -0.1 -0.3 -0.2 1.4 -0.1 1.4 0.6 1.1 -0.7 -1.4
0035 0.3 -1.1 -0.8 -0.3 -0.6 -1.3 -1.7 -1.3 1.8 1.5 0.4 -0.2 -0.8 1 0.5 1.4 0.4 1.7 0.6 -0.8
0036 0 -0.5 -0.9 -0.1 -0.2 -0.6 -1.1 -0.2 1.7 1 -0.7 -0.3 -0.2 0.3 -0.1 0.5 -0.5 3 0.1 -0.4
0037 0 0.5 -0.3 0.1 -0.7 -0.3 3.6 0.9 -0.6 -0.1 -1 0.8 -0.9 -0.6 -0.7 0 -0.3 0.2 -0.7 0.8
0038 0.4 1.2 0.6 1.8 0.7 0.4 3.4 1.7 -1.5 -1.4 -1.5 -0.6 -1 -1.2 -0.4 0.1 -0.7 -0.2 -1.2 0.9
0039 -0.7 0 0.4 0.7 0.8 0.3 -1.1 0.8 -0.6 1.3 1.1 1.1 -0.1 -0.5 0.5 -0.3 0.2 -0.7 -1.1 -0.8
0040 0.1 -0.4 0.4 -0.3 1.2 -0.4 -0.6 -0.6 -0.4 0.1 0.3 -0.1 -0.4 -0.2 -0.3 0.6 0.2 1.1 0.3 -0.5
0041 0.1 -0.4 0.2 0.4 1.2 -0.6 -1 -0.5 0.8 1.4 0.1 0.7 -0.1 -0.2 0.6 0.6 0.7 -1 -1.2 -0.7
0042 0.1 -0.6 0.3 0.3 0.4 -0.7 -0.7 0.1 0.1 -0.7 0.6 0.4 0.3 0.7 -0.6 0.1 0.6 0.1 0.2 -1
0043 0.2 -0.1 0.6 1.5 1.1 -0.3 -1.3 -1.1 -0.1 1.3 0.5 -0.5 -1.5 -0.9 0.3 0.2 0.3 0.1 -0.1 -0.9
0044 0.5 -1.3 -0.7 -0.4 -0.1 -1.2 -1.2 -0.9 1.2 0.4 0.2 0.5 -0.7 0.4 -0.1 1.1 0.6 1.2 -0.9 -1
0045 0.2 -1 -0.6 0 0 -1.1 -1.7 -1.3 0.7 0.7 -0.6 -0.1 -0.6 0.6 0.3 0.9 1.3 0.9 0.5 -1.2
0046 0.3 -1.1 -1.1 0.3 -0.5 -1.1 -1.4 -1.4 0.3 0.3 0.8 0.8 -0.1 0.5 0.6 0.7 0.5 2.4 -0.2 -1.1
0047 0.3 -1.6 -0.2 0.2 0.1 -0.6 -1.5 -1.2 0 0.8 1.4 1.2 0.3 0.1 1.1 0.5 0.2 0.3 0 -0.8
0048 0.1 -0.2 0.6 0.3 0.8 -0.8 -1.2 -0.5 -0.7 0.3 1 1.1 -0.2 -1 0.7 0.6 0.4 -0.3 -0.8 -0.1
0049 0.1 -1 0 0.2 0 -0.7 -0.3 -0.2 0.2 -0.2 0.3 0.7 0.1 0.5 -0.4 0.7 0.4 0.1 0.1 -0.4
0050 0.3 1.2 1 0.9 0 0.3 0.7 1 -0.6 -0.6 -0.8 -0.6 -0.2 -0.6 -0.2 0.6 -0.5 -0.9 -0.7 -0.1
0051 0 -0.7 0.5 1 1.4 0 -0.3 0.3 -0.7 0.1 0 -0.8 -0.3 -0.4 -0.6 0.6 0.6 -0.3 -0.1 0.1
0052 0.2 -0.6 -0.2 0.7 0 -0.3 -0.7 -0.2 -0.4 -0.2 -0.2 -0.4 0 -0.7 -0.1 0.6 0.2 0.4 1.9 -0.4
0053 1.2 -0.5 0.5 0.3 0.7 -0.6 -1.3 -1 -1.6 0.1 0.9 0.8 -0.3 -0.3 -0.2 1.1 0.7 0.3 0.1 -0.1
0054 0.6 -1.1 -0.1 0.1 0.2 -0.5 -1.2 -0.7 0.3 0.8 0.2 0.3 -0.5 0.5 0 1.4 0.7 0.6 -0.6 -0.7
0055 0.1 -0.2 0.2 1 0.2 -0.1 -0.2 -1.4 0.1 -0.2 -0.2 0.2 -0.1 -0.3 0.1 0.8 0.2 -0.6 -0.4 0.9
0056 0.4 0.4 -0.1 0.7 0.1 -0.1 -0.2 -0.1 -0.3 0.3 -0.1 0 -0.3 -0.8 -0.8 0.9 -0.2 0 0.1 -0.1
0057 0 -1 0.2 0.3 0.7 -0.6 -0.8 -0.9 0.2 0.5 0.6 0.6 -0.7 -0.2 0.5 1 1 -0.2 0 -0.9
0058 0.3 -0.3 0.7 1.2 1.1 -0.4 -1.3 -0.7 -0.1 1.1 1 0.7 -1.2 -0.8 -0.3 0.1 0.1 -0.9 1.5 -0.6
0059 0.3 -0.2 0.9 0.6 1.1 -0.3 -1.3 -0.1 0.3 0.5 -0.1 -0.1 -0.5 -0.2 0 0.5 0.4 -0.8 -0.3 -0.5
0060 0.4 -0.5 -0.1 0.1 0.4 -0.9 -2 -0.8 0.9 1 0.5 0.4 -0.3 0.5 0.2 0.8 0.5 0.6 1.2 -1.4
0061 0.6 -1.3 -0.3 -0.3 0 -1.1 -2.2 -0.9 0.7 0.7 0.1 0.2 -0.4 0.4 0 1.1 0.4 0.4 1.2 -1.6
Select residue pair below:
i_j Score Prob
0013_0020 3.303 1.00
0039_0048 2.778 1.00
0040_0051 2.766 1.00
0007_0021 2.765 1.00
0010_0022 2.478 1.00
0028_0041 2.390 1.00
0031_0039 2.375 1.00
0041_0048 2.283 1.00
0051_0056 2.217 1.00
0003_0032 2.138 1.00
0025_0042 2.096 1.00
0004_0026 1.960 1.00
0006_0057 1.717 1.00
0004_0028 1.713 1.00
0021_0027 1.505 1.00
0038_0053 1.410 1.00
0042_0045 1.377 0.99
0010_0023 1.376 0.99
0006_0026 1.366 0.99
0005_0058 1.363 0.99
0022_0025 1.345 0.99
0008_0057 1.345 0.99
0027_0040 1.341 0.99
0042_0047 1.322 0.99
0005_0029 1.300 0.99
0049_0052 1.251 0.99
0003_0058 1.177 0.98
0026_0059 1.123 0.97
0052_0055 1.079 0.95
0005_0056 1.072 0.95
0019_0040 1.068 0.95
0012_0020 1.053 0.95
0030_0041 1.046 0.94
0032_0038 1.045 0.94
0006_0059 0.939 0.89
0039_0050 0.939 0.89
0018_0050 0.904 0.86
0036_0053 0.880 0.84
0007_0025 0.860 0.82
0025_0043 0.833 0.79
0011_0014 0.805 0.76
0012_0022 0.761 0.70
0021_0051 0.735 0.66
0032_0058 0.703 0.61
0009_0055 0.688 0.59
0009_0054 0.687 0.58
0043_0046 0.687 0.58
0013_0018 0.668 0.55
0030_0048 0.657 0.53
0019_0042 0.653 0.53
0037_0055 0.613 0.46
0037_0040 0.612 0.46
0052_0056 0.591 0.42
0022_0042 0.584 0.41
0004_0059 0.580 0.40
0027_0042 0.574 0.39
0003_0029 0.572 0.39
0003_0028 0.566 0.38
0040_0056 0.563 0.38
0033_0039 0.549 0.35
0018_0036 0.544 0.35
0027_0051 0.530 0.32
0049_0056 0.523 0.31
0006_0024 0.521 0.31
0019_0049 0.501 0.28
0023_0036 0.495 0.27
0021_0042 0.488 0.26
0033_0053 0.482 0.26
0029_0040 0.474 0.25
0033_0050 0.459 0.23
0029_0041 0.451 0.22
0007_0010 0.451 0.22
0004_0061 0.446 0.21
0033_0038 0.437 0.20
0042_0046 0.431 0.20
0028_0043 0.430 0.19
0044_0047 0.423 0.19
0002_0029 0.421 0.18
0011_0018 0.417 0.18
0036_0050 0.411 0.17
0035_0039 0.405 0.17
0017_0039 0.404 0.17
0007_0027 0.399 0.16
0049_0055 0.394 0.16
0004_0029 0.390 0.15
0011_0055 0.387 0.15
0031_0035 0.387 0.15
0004_0060 0.378 0.14
0041_0049 0.377 0.14
Local Interactions:
i_j Score Prob
0054_0055 1.510 1.00
0015_0017 1.509 1.00
0042_0043 1.168 0.97
0034_0036 1.162 0.97
0045_0047 1.084 0.96
0014_0015 1.076 0.95
0045_0046 1.003 0.93
0017_0018 0.985 0.92
0020_0021 0.960 0.90
0042_0044 0.948 0.89
0035_0036 0.941 0.89
0031_0033 0.857 0.82
0003_0004 0.856 0.82
0043_0045 0.797 0.75
0034_0035 0.771 0.71
0053_0054 0.751 0.69
0029_0030 0.738 0.67
0044_0046 0.718 0.64
0008_0009 0.714 0.63
0059_0060 0.700 0.61
0055_0056 0.681 0.57
0057_0059 0.667 0.55
0060_0061 0.660 0.54
0049_0051 0.647 0.52
0043_0044 0.639 0.50
0025_0027 0.631 0.49
0006_0008 0.630 0.49
0009_0011 0.626 0.48
0044_0045 0.624 0.48
0013_0014 0.619 0.47
0020_0022 0.612 0.46
0058_0059 0.610 0.45
0052_0054 0.601 0.44
0053_0055 0.580 0.40
0003_0005 0.570 0.39
0056_0057 0.554 0.36
0026_0028 0.534 0.33
0032_0033 0.534 0.33
0051_0052 0.522 0.31
0012_0013 0.512 0.30
0015_0016 0.504 0.29
0046_0047 0.496 0.28
0033_0035 0.486 0.26
0021_0022 0.480 0.25
0011_0013 0.475 0.25
0022_0023 0.462 0.23
0058_0060 0.455 0.22
0049_0050 0.438 0.20
0010_0012 0.413 0.18
0012_0014 0.410 0.17
0030_0031 0.398 0.16
0048_0049 0.392 0.16
0055_0057 0.387 0.15
See all coupling residues
Download raw data
Renumber residues to start with:
Position: 1 2 3 4 5 ...
Sequence: M A P W A ...
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