>seq_1
MLSRRGHRLSRFRKNKRRLRERLRQRIFFRDKVVPEAMEKPRVLVLTGAGISAESGIRTFRAADGLWEEHRVEDVATPEGFDRDPELVQAFYNARRRQLQ
QPEIQPNAAHLALAKLQDALGDRFLLVTQNIDNLHERAGNTNVIHMHGELLKVRCSQSGQVLDWTGDVTPEDKCHCCQFPAPLRPHVVWFGEMPLGMDEI
YMALSMADIFIAIGTSGHVYPAAGFVHEAKLHGAHTVELNLEPSQVGNEFAEKYYGPASQVVPEFVEKLLKGLKAGSIA
>tr|A0A0D1MS59|A0A0D1MS59_ENTAE NAD-dependent deacetylase OS=Enterobacter aerogenes GN=SR38_03850 PE=3 SV=1
MLSRRQHRLMRFKRNKRRLRERLRQRLFFQNG-VPEAMDKPRVVVLTGAGISAESGIRTFRATDGLWEEHRVEDVATPEGFARDPQLVQAFYNARRRQLQ
QPDIKPNPAHLALAELEQALGDRFLLITQNIDNLHERAGNHNIIHMHGELLKVRCAQSGQILEWTHDVTDQDKCHCCQFPAPLRPHVVWFGEMPLGMDDI
YQALAMADVFIAIGTSGHVYPAAGFVHEARLHGAHTVELNLEPSQVGSEFEEKHYGLASKVVPEFVERLLKGL------
>tr|A0A0L0GYU8|A0A0L0GYU8_9ENTR NAD-dependent deacetylase OS=Trabulsiella odontotermitis GN=GM31_18905 PE=3 SV=1
MLTRRLHRLSRFRRNKRRLRERLRQRIFFRDKVMPEAMEKPRVVVLTGAGISAESGIRTFRAADGLWEEHRVEDVATPEGFARDPALVQAFYNARRRQLQ
QPEIAPNAAHKALARLEEALGDRFTLVTQNIDNLHERAGSQRVIHMHGELLKVRCSWSGQVLEWTGDVTADDKCHCCQFPALLRPHVVWFGEMPLGMDDI
YSALATADVFIAIGTSGHVYPAAGFVHEAKLHGAHTVELNLEPSQVGSEFEEKHYGLASEVVPEFVEKLLKGL------
>tr|W0HYC5|W0HYC5_9ENTR NAD-dependent deacetylase (Regulatory protein SIR2-like protein) OS=Sodalis praecaptivus GN=npdA PE=3 SV=1
--MRIHRRLIRFRKSKRLRQQRLRARIFHRDSLAVTKMKKPFVVVLTGAGISAESGIRTFRAEDGLWEEHRVEDVATPEGFARNPALVQAFYNARRRQLL
QPEIAPNPAHLALAELEQMLGDNFLLITQNIDNLHERAGNRRIIHMHGELLKVRCSQSGQILEWRDDVTEADRCHCCQFPAVLRPHVVWFGEMPLGMDDI
YHALARADYFLAIGTSGHVYPAAGFVHEARLCGARTVELNLAPSQVESQFEEKYYGPASRCVPQWTREFIDGF------
>tr|A6VP34|A6VP34_ACTSZ Silent information regulator protein Sir2 OS=Actinobacillus succinogenes (strain ATCC 55618 / 130Z) GN=Asuc_1371 PE=3 SV=1
------------------------------------MNKRPKIVVLTGAGISAESGIRTFRAADGLWENHKVDEVATPEGFLRNPALVQNFYNERRQKLF
DPAVKPNAAHTALVKLEQAIGDNFLLVTQNVDNLHERAGSKNLIHMHGDLLTVRCEWSGKTYHWERDVTDKDHCDCCSPPRRLRPHIVWFGEMPLEMERI
YAALSECDYFIAIGTSGNVYPAAGFVQEANRFGAKTVELNLEPSLTRSRFSRQRYGKATKIVPIFVDELLTEL------
>tr|W0RB73|W0RB73_BIBTR Uncharacterized protein OS=Bibersteinia trehalosi USDA-ARS-USMARC-190 GN=F544_14150 PE=3 SV=1
------------------------------------MKKDLKIVVLTGAGISAESGIRTFRAEDGLWENHRVEDVATPEGYKRDPELVQRFYNERRRKLF
DPEVQPNAAHLALAKLEEKLGENLLIVTQNVDNLHERAGNQNIIHMHGELLKVRCPNKGTVYDWQGDVKDEDHCTCCQIPRKLRPHIVWFEEMPLEMDRI
YSALMECDIFISIGTSGNVYPAAGFVQEANNWGAKTIELNLEPSLVKNAFQEARYGKASEIVPAFVTEVLEAI------
>tr|I3TXG4|I3TXG4_TISMK NAD-dependent deacetylase OS=Tistrella mobilis (strain KA081020-065) GN=npdA PE=3 SV=1
--------------------MRWIDRFDPE----DDVTPDLPIVVLTGAGISKESGLDTFRDADGVWRRHSLEDLATPEGFARNPALVQGFYNSRRTQLA
--TVQPNPAHQALARLEAAWPGGVLVVTQNVDDLHERAGSRNLIHMHGELAKVRCLECEAVAHHLADLDEASACGGCGSTGRMRPHIVWFGEMPFEMERI
WAALAGCGLFVSVGTSGTVYPAAGFVADVRHRGAHTLELNLEPSEGASLFAETRYGPASLIVPAFVDELLGRL------
>tr|M2TQ68|M2TQ68_9PROT NAD-dependent protein deacetylase of SIR2 family OS=alpha proteobacterium JLT2015 GN=C725_0863 PE=3 SV=1
----------------------------MS----NPAAQPRSIVILTGAGISAESGVPTFRGPDGLWEGHRVEDVATPEAFARDPDLVQSFYDARRAALG
--GVKPNAAHQALGRLDAAFDGDLLIVTQNVDDLHERGGARRLLHMHGELLRASCTVCGVRQPAPAVLREGAACESCEAGGTLRPDIVWFGEMPHGMGHI
EAALADADLFVSIGTSGAVYPAAGFVRTAAAYGARTLELNLEPSEGTALFDEARHGPATRLVPAWADEILGCN------
>tr|A0A0D6YKL5|A0A0D6YKL5_MASLA NAD-dependent deacetylase OS=Mastigocladus laminosus UU774 GN=SP67_12035 PE=3 SV=1
------------------------------------MNEIHSIVILTGAGISAESGVATFRGPDGLWEGHRVEDVATPEAFARDPALVQAFYDARRARLA
--SVAPNAAHHALARLDAEWPGDLLIVTQNVDDLHERAGARRLLHMHGELKSAWCLACDERMRWSAPLSDGPACAACGAPGKLRPDIVWFGEMPYEMERI
DRALMDADLFVSIGTSGAVYPAAGYVQTARYAGARTLELNLEPSQGSVFFHESRIGPAGQLVPKWVDEMLGG-------
>tr|A0A0N0JU42|A0A0N0JU42_9PROT NAD-dependent deacetylase OS=alpha proteobacterium AAP81b GN=IP88_12155 PE=3 SV=1
-------------------------------------MTPRNLVILTGAGISAESGVPTFRGPDGLWEGHRVEDVATPQAFRRDPVLVQRFYDLRRAALA
--KVEPNAAHHALARLDAEWPGELLLVTQNVDDLHDRAGSRRLRHMHGELKSALCAGCGAAMPWEGDLSNAPACRRCGA-ARLRPDIVWFGEMPYHMEAI
AAAIAACDLFVSIGTSGAVYPAAGFVDWAREAGAATLELNLDPSAGTPLFDEARHGPATALVPAWVAEVLAAV------
>tr|A0A0J8Y985|A0A0J8Y985_9ENTR NAD-dependent deacetylase OS=Cronobacter sp. DJ34 GN=ACH50_14770 PE=3 SV=1
MLSRRQHRLSRFRRNKRRLRERLRQRIFFRDTGVPEVMEKPRVVVLTGAGISAESGIKTFRAADGLWEEHHVEDVATPEGFARNPALVQRFYNERRRQLQ
QAEVQPNAAHLALARLEQALGDRFLLITQNIDNLHERAGNENVLHMHGELLKVRCERSGQVLAWTGDVTTQDKCHCCQFPSPLRPHVVWFGEMPLGMDRI
YEALAMADVFIAIGTSGHVYPAAGFVHEAKLQGAHTVELNLEPSQVGSEFEEKHYGLASQVVPEFVDKLLKGL------
>tr|A0A0M2C2T9|A0A0M2C2T9_ENTCL NAD-dependent deacetylase OS=Enterobacter cloacae UCICRE 3 GN=L414_01875 PE=3 SV=1
MLSRRQGRLSRFRKNKRRLRERLRQRIFFRDRMMPEAMDKPRVVVLTGAGISAESGIQNFRAADGLWEEHRVEDVATPEGFARDPALVQAFYNARRRQLQ
QPEIAPNAAHLALAKLEEALGDRFLLVTQNIDNLHERAGNHNIIHMHGELLKVRCAWSGQVLEWKEDVLDEDRCHCCQFPSRLRPHVVWFGEMPLGMDEI
YSALAMADVFIAIGTSGHVYPAAGFVHEARLQGAHTVELNLEPSQVGSEFEEKHYGLASEVVPAFVDKLLKGL------
>tr|A0A071LVY4|A0A071LVY4_9ENTR NAD-dependent deacetylase OS=Mangrovibacter sp. MFB070 GN=DT73_11570 PE=3 SV=1
MQSRRLHQQCRFKKNKRRLRERLRQRIFFRDRMVPETMEKPKVVVLTGAGISAESGIRTFRAADGLWEEHRVEDVATPEGFARDPKLVQAFYNARRSQLQ
APDIKPNAAHLALARLEAELGENFLLVTQNIDNLHERAGNKHIIHMHGELLKVRCSQSGHIYKWNQDVTPQDRCHCCQIPAVLRPHVVWFGEMPLGMDEI
YHALAGADYFIAIGTSGHVYPAAGFVHEARLQGAHTVELNLEPSQVGNEFEECHYGLASEVVPEYVEKLLQSL------
>tr|A0A0J9BKC9|A0A0J9BKC9_9BACT NAD-dependent deacetylase OS=bacteria symbiont BFo2 of Frankliniella occidentalis GN=AI29_02660 PE=3 SV=1
TSNRRRIRVARFKKNKRKMRQRFRQSYFEDARIALVSKPLPKVVVLTGAGISAESGIATFRAADGLWENHAIEDIATPEGYHRDPQQVHNFYNERRRQLQ
SAKIMPNNAHRALAKLGTLLGDNLLVVTQNIDNLHERASSANIIHMHGELLKARCTQSQQVITWLDDLQPTDRCTCCQFPAPLRPHVVWFGEMPLQMEGI
YQAIAECDIFIAVGTSGQVYPAAGFVHEAKIQGAETIEFNLEPTASKEEFIEGHYGPASQTLPAWVEMFLSQC------
>tr|E1SJR9|E1SJR9_PANVC Putative nicotinic acid mononucleotide:5,6-dimethylbenzimidazole (DMB) phosphoribosyltransferase OS=Pantoea vagans (strain C9-1
RTPRRRIRLARLKKTRRKVHQRFRQRIFERDRQALAAHPQPHVVVLTGAGISAESGIRTFRAADGLWEDHHVEDVATPEGFQRDPALVQRFYNARRQQLQ
EADIQPNAAHLALAELEQVLGDNFLLVTQNIDNLHERAGNSRVLHMHGELLKVRCVTSGQVIEWTGDITPDDRCTCCQFPSALRPHVVWFGEMPLGMEQI
YQALEQADYFIAIGTSGHVYPAAGFVHEAKLQGAHTVELNLEPSQVGNEFAERHYGLASEVVPEFVHKLLRGL------
>tr|A0A0A7RX74|A0A0A7RX74_9GAMM NAD-dependent protein deacetylases, SIR2 family OS=Frischella perrara GN=FPB0191_00006 PE=3 SV=1
-------------------------------------MAIPKIVVLTGAGISAESGLATFRAQNGLWEGHNVNDVATYEGYLRDPILVHNFYNMLRNQLQ
QPTVKPNPAHLSLAELETKLGDNVTIITQNVDNLHEQAGSKNVLHMHGELLKVRNEKTGQIFDCYQDI-------CYTDNKLIRPHIVWFGEIPLYMEQI
YQQLAQADYFIAIGTSGHVYPAAGFVQFANEYGVKTIELNLEPSLKENQFSSKIYGPASQIVPSFVAQLLAEL------
>tr|A0A0F8YJJ6|A0A0F8YJJ6_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_2889690 PE=3 SV=1
----------------------------------MSKKHYEAVVVLTGAGISAESGIRTFRASDGLWEDHHIEDVASPEGFAKDPDKVHLFYNQRRDQLL
NQGIEPNPAHLALANFEQRFSGTYTLITQNIDDLHERAGSNSPLHMHGELLKIRCHQSGRIFECRENTTPLSKCPCCRMPGNLRPHVVWFGEMPLFMNEI
YQALNSCDLFIAIGTSGNVYPAAGFFETAKMAGAHTAELNLEPSINSSQFDEQHDGPASEVIPHYFKALLTG-------
>tr|C5S1M1|C5S1M1_9PAST NAD-dependent deacetylase OS=Actinobacillus minor NM305 GN=AM305_08996 PE=3 SV=1
-------------------------MIF-QPLFVGEIMNLPKVVILTGAGISAESGIRTFRASDGLWEDHHIDDVATPEGFRRNPALVQRFYNERRRQLT
SPDIQPNAAHLALAKLEQTLGDNLLIVTQNVDNLHERAGSKNVIHMHGELLQVRCVKSGKVYEWYKDVTDSDRCTCCEPSNVLRPNIVWFGEIPFEMKQI
QTALQQCDYFVAIGTSGNVYPAAGFVRETHPYRCKTIEINLEPSKVKSHFDEVRIGKAGTLVPEWVEELLAKF------
>tr|E6W862|E6W862_PANSA Silent information regulator protein Sir2 OS=Pantoea sp. (strain At-9b) GN=Pat9b_1509 PE=3 SV=1
RTLRRRLRLARYKKTRRKVHQRFRQRIFERDRKALAAHPLPHVVVLTGAGISAESGIRTFRAADGLWEEHRVEDVATPEGFQRDPALVQAFYNARRRQLQ
QPDIQPNAAHLALAELEQVLGDNFLLVTQNIDDLHERAGSQRVLHMHGELLKVRCVSSGQVIDWTDDLTPDDRCTCCQFPSALRPHVVWFGEMPLGMEEI
YQALADADVFIAIGTSGHVYPAAGFVHEAKLQGAHTVELNLEPSQVGNEFAEGQYGLASVEVPAFVHTLLRGL------
>tr|D4GC72|D4GC72_PANAM NpdA OS=Pantoea ananatis (strain LMG 20103) GN=npdA PE=3 SV=1
RTPRRRLRLARLKKTRRKVHQRFRQRIFERDRQALAAHPLPRIVVLTGAGISAESGINTFRAADGLWEEHRVEDVATPEGFRRDPALVQRFYNARRQQLQ
QPEIQPNAAHLALAELEQVLGDNFLLVTQNIDNLHERAGNSRVLHMHGELLKVRCANSGQVIDWHEDVTAEDRCTCCQFPSVLRPHVVWFGEMPLGMEEI
YQALEQANLFIAIGTSGHVYPAAGFVHEAKLQGAHTVELNLEPSQVGNEFAESYYGLASEVVPAFVHKLLHAL------
>tr|A0A0K0HP51|A0A0K0HP51_HAFAL NAD-dependent deacetylase OS=Hafnia alvei GN=PU01_15140 PE=3 SV=1
--MRTRHRICRFRKNKRLRHQRFRSRIFHRDTLCGGCMTKPYVVVLTGAGISAESGIRTFRAADGLWEEHRVEDVATPEGYHRDPELVQSFYNARRQQLQ
QPEIQPNAAHLALAELERQLGDNFVLVTQNIDNLHERAGNSRIIHMHGELLKVRCTQSGQVIEWKGDLTIDDRCHCCQFPAPLRPHIVWFGEMPIGMDEI
YDALAKADYFIAIGTSGHVYPAAGFVHEAHLNGAHTIELNLEPSQVESQFDEKHYGAASQVVPEYVRELLEEI------
>tr|A0A085H5Y5|A0A085H5Y5_9ENTR SIR2 family NAD-dependent protein deacetylase OS=Kluyvera ascorbata ATCC 33433 GN=cobB PE=3 SV=1
MQSRRLHRLSRFRRNKRQLRQRLRQRIFFTDRVMPEEMDKPRVVVLTGAGISAESGIRTFRAADGLWEEHRVEDVATPEGYHRDPELVQRFYNERRRQLQ
QAEIAPNAAHLALARLEEALGENVLVVTQNIDNLHERAGNKNVLHMHGELLKVRCTQSGQVFDWPGDLTVDDRCHCCQFPAPLRPHIVWFGEMPFEMDHI
YMALARADIFIAIGTSGHVYPAAGFVHEAKLHGAHTVELNLEPSQVGSEFEEKHYGLASEVVPAYVAKLLKEM------
>tr|C6CFF3|C6CFF3_DICZE Silent information regulator protein Sir2 OS=Dickeya zeae (strain Ech1591) GN=Dd1591_1652 PE=3 SV=1
--MHSRQRLHRFRQRKRLRHQRLCARIFHLDYLVVKNVNKPRVVVLTGAGISAESGIRTFRASDGLWEEHRVEDVATPEGFHRDPQTVQNFYNQRRRQLQ
QPEIVPNAAHLALAELEAALGDHFLLVTQNIDNLHERAGNKRIIHMHGELLKVRCSHSGQVFEWTDDVSVDDRCHCCQFPAPLRPHVVWFGEMPLGMDRI
YHALSEANFFIAIGTSGHVYPAAGFVHEAHVHGAHTVELNLEPSQIQSQFDEHIYGPASKVVVEFVHNWLARY------
>tr|A0A0Q4LTF2|A0A0Q4LTF2_9ENTR NAD-dependent deacylase OS=Serratia sp. Leaf50 GN=ASE93_19140 PE=4 SV=1
--MRTRHRLRRFRKNKRIRHQRFRSNIFHRDSMAAAELKRPFVVVLTGAGISAESGIRTFRAADGLWEDHKVEDVATPEGFRRDPEQVQAFYNARRQQLQ
QEEIQPNAAHQALAVLEEALGDNFLLVTQNIDNLHERAGSSRILHMHGELMKVRCSESGQVFDWPKDLSVDDRCHCCQFPAPLRPHVVWFGEMPLRMDEI
YTALAKADFFIAIGTSGHVYPAAGFVHEAHIQGAHTFELNLEPSQVESQFDERIYGPASTVVPEFVHAFLTNK------
>tr|A0A068Z7J0|A0A068Z7J0_9ENTR Deacetylase of acetyl-CoA synthetase,NAD-dependent OS=Serratia symbiotica GN=cobB PE=3 SV=1
--MHTRHRLCQFRKSKHVLHQRFRSRIFYRDIMAVAELKKPFVVVLTGAGISAESGIRTFRTADGLWEQHRVEDVATPEGYQRNPVLVQEFYNARRRQLQ
AAEVAPNAAHRALADLEAWMGENFLLVTQNIDNLHERAGNKRVLHMHGELLKVRCTHSGQVFDWSEDLSVEDRCHCCQLSAPLRPHVVWFGEMPLGMDEI
YQALAKADFFIAIGTSGHVYPAASFVQEARLAGAYTMELNLEPSQVENQFNEKHYGPASEVVPHFVHKFLVGK------
>tr|A0A0N0Z9V6|A0A0N0Z9V6_9ENTR SIR2 family NAD-dependent protein deacetylase OS=Moellerella wisconsensis ATCC 35017 GN=M992_1742 PE=3 SV=1
-MMRYRHRTKKFRKIKHLRRQRSRGRLFYQDYKS-TPTTLPKIVVLTGAGISAESGIRTFRSSDGLWEEHRVEDVATPEGFARDPLLVQNFYNDRRRQLQ
QPDIQPNPAHYALAELEKVLGDNFLLVTQNIDNLHEQAGNQRIIHMHGELLKVRCCGSNQVLSWKGDLSVDDKCHCCQFPQPLRPHVVWFGEMPLGMDQI
YHALEQADIFIAIGTSGHVYPAAGFVHEAKLNGAHTVELNLEPSQVESQFDEKHYGLASQLVDDYVEVLLRAV------
>tr|D2TYV4|D2TYV4_9ENTR NAD-dependent deacetylase OS=Arsenophonus nasoniae GN=ARN_13370 PE=3 SV=1
-MMRFHCRLRKLRKKKNLHRQRFRCCLFYREKQLIDKMKRKKIVILTGAGISAESGIRTFRATDGLWEEHRVDDVATPEGFVRDPELVQRFYNQRRYQLQ
QPDIKPNAAHYALAKLEHLLGDNFLLVTQNIDNLHEKAGNRRIIHMHGELLKARCCQSGQVIDWKGDLTTNDRCHCCQFPQPLRPHIVWFGEMPLGMEMI
YQALSSVDIFIAIGTSGHVYPAAGFVHEAKLAGAHTVELNLEPSQVESQFDEKYYGSATKIVEKYIDGLVAEI------
>tr|K8W953|K8W953_9ENTR NAD-dependent deacetylase OS=Providencia sneebia DSM 19967 GN=OO7_10597 PE=3 SV=1
-MLHFRHRLKKFKKIKMLRRQRARNLSFYRESRI-TNMKKIKVVVLTGAGISAESGIRTFRSSDGLWEEHRVEDVATPEGFARDPRLVQRFYNERRKQLQ
QDNIKPNAAHFALAQLEDVLGDDFLLVTQNIDNLHERAGSKRIIHMHGELLKVRCSWSQQVVEWKGDLSVDERCHCCQFPQPLRPHIVWFGEMPFGMDHI
YQSLEEATIFIAIGTSGHVYPAAGFVHEAKLHGAHTVELNLEPSQVESEFDEKHYGLASQIVVEYINNLIYEL------
>tr|B2PZ27|B2PZ27_PROST Transcriptional regulator, Sir2 family OS=Providencia stuartii ATCC 25827 GN=PROSTU_02942 PE=3 SV=1
-MLRFRHRLKKLKKIKMLRRQRARDRFFYSENRI-TNMKNVKVVVLTGAGISAESGIQTFRSSDGLWEEHRVEDVATPEGFARDPQLVQRFYNERRRQLQ
QENIKPNPAHYALAQLEDLLGDNFLLVTQNIDNLHERAGSKRIIHMHGELLKVRCSWSNQVLEWKGDLSTDERCHCCQFPQPLRPHIVWFGEMPLGMDEI
YQAIENATLFIAIGTSGHVYPAAGFVHEARLNGAHTVELNLEPSQVESEFEEKHYGLASEVVVDYVKHLIAEL------
>tr|D8MQV2|D8MQV2_ERWBE NAD-dependent deacetylase OS=Erwinia billingiae (strain Eb661) GN=npdA PE=3 SV=1
RTPRRRLRLARYKKTRRQVHQRFRQRIFERDRNIIAQHPLPRVVVLTGAGISAESGIRTFRAADGLWEDHKVEDVATPEGFARDPQKVQDFYNARRRQLQ
QPEIQPNAAHEALAELEAALGDHFLLVTQNIDNLHERAGNSHVIHMHGELLKVRCATSGQILHWGDDVKPEDRCHCCQFPSVLRPHVVWFGEMPLQMDEI
YAALSEADYFVAIGTSGHVYPAAGFVHEAKLQGAHTVELNLEPSQVGSEFEEKDYGLASEVVPKFVHNLLAKI------
>tr|A0A0Q4N083|A0A0Q4N083_9ENTR NAD-dependent deacylase OS=Erwinia sp. Leaf53 GN=ASF13_05710 PE=4 SV=1
RTPRRRLRLARDKKNRRKVQQRFRQRIFERDRNLIAMHPLPRVVVLTGAGISAESGIQTFRAADGLWESHRVEDVATPEGFQRNPERVQEFYNARRQQLQ
QPEIQPNAAHLALAELESALGDRLLLVTQNIDNLHERAGNRNVIHMHGELLKVRCVSSGQVLHWNDDVKPDDRCHCCQFPSRLRPHVVWFGEMPLHMEEI
YQALAEADYFVAIGTSGHVYPAAGFVSEAKLQGAHTLELNLEPSQVGSEFAEAQYGLASEVVPAWVRGLLDGL------
>tr|A0A0M2KEJ5|A0A0M2KEJ5_9ENTR NAD-dependent deacetylase OS=Erwinia tracheiphila GN=SY86_09530 PE=3 SV=1
RNPRRRLRLARYKKNRRQVHQRFRQRIFERDRNIIAQNPLPRVVVLTGAGISAESGIRTFRAEDGLWEDHKVEDVATPEGFTRDPERVQVFYNARRRQLQ
QPDIAPNAAHLALAKLEAALGDHFLLVTQNIDNLHERAGNHNIIHMHGELLKVRCTGSGQVVSWQDDVNPGDRCHCCQFPSTLRPHIVWFGEMPLQMDEI
YTALSQADYFVAIGTSGHVYPAAGFVHEAKLQGAYTVELNLQPSQVGSEFEENDYGPASEVVPRFVQSLLRKT------
>tr|A0A0J8YK21|A0A0J8YK21_9BACT NAD-dependent deacetylase OS=bacteria symbiont BFo1 of Frankliniella occidentalis GN=AI28_14905 PE=3 SV=1
RTPRRRLRLARYKKTRRQVHQRFRQRIFERDRNIIARHPLPRVVVLTGAGISAESGIQTFRAADGLWEEHKVEDVATPEGFARNPELVQQFYNLRRQQLQ
QPAIQPNAAHLALAELEAALGDHFLLVTQNIDNLHERAGNRNVIHMHGELLKVRCVSSGQVLHWTEDVKPDDRCHCCQFPSVLRPHVVWFGEMPLQMDEI
YQALAQADYFVAIGTSGHVYPAAGFVHEARLQGAHTVELNLEPSQVGSEFEEKQYGLASEVVPEWVHDLLENI------
>tr|E3DDB8|E3DDB8_ERWSE Putative nicotinic acid mononucleotide:5,6-dimethylbenzimidazole (DMB) phosphoribosyltransferase OS=Erwinia sp. (strain Ejp617)
RTPRRRLRLARYKKTRRQVHQRFRQRIFERDRNIIARDRLPRVVVLTGAGISAESGIKTFRAADGLWEDHKVEDVATPEGFARNPQRVQDFYNQRRRQLQ
QPDVQPNAAHLALAELEAALGDHFLLVTQNIDNLHERAGNRNVIHMHGELLKVRCSNSGQTLHWNEDVKPNDRCHCCQFPSVLRPHIVWFGEMPLQMDDI
GQSIAEADYFVAIGTSGHVYPAAGFVHEARLQGAHTIELNLEPSQVGSEFEQKHYGLASQVVPEWVHNVLKMI------
>tr|J9JQM3|J9JQM3_ACYPI Uncharacterized protein OS=Acyrthosiphon pisum PE=3 SV=2
------------------LRLMVPTRIFERDRKALAAHPQPRVVVLTGAGISAESGIQTFRAADGLWEEHRVEDVATPEGFHRNPDLVQGFYNARRRQLQ
QPEIQPNAAHKALAELEQVLGDNFLLVTQNIDNLHERAGSQRVLHMHGELLKVRCESSGQVLDWTEDVKPDDRCTCCQFPARLRPHVVWFGEMPLGMEEI
YQAIEKANLFIAIGTSGHVYPAAGFVHEAKLQGAHTVELNLEPSQVGNEFAESQYGLASEVVPDFVHTFLRGL------
>tr|H6SNL9|H6SNL9_RHOPH NAD-dependent deacetylase OS=Pararhodospirillum photometricum DSM 122 GN=RSPPHO_02724 PE=3 SV=1
-----------------------------------RASAIPSLVLLTGAGISRESGLDTFRDADGVWSRVRLEDVATPEGFERDPVKVHAFYNARRHGLR
DPEVVPNAAHLALARLERLWPAEVLLVTQNIDDLHERAGSPAPLHMHGELLKARCAACDAVLPWADDLGLEDRCPSCGAEATLRPHVVWFGEMPLEMERI
EAALTACGVFVSIGTSGTVYPAAGFVSLARRAGARTVELNLEPSHGASLFHECHHGPATGVVPAFVEALLASAP-----
>tr|B6IVE2|B6IVE2_RHOCS NAD-dependent deacetylase OS=Rhodospirillum centenum (strain ATCC 51521 / SW) GN=RC1_2898 PE=3 SV=1
-----------------------------------DLSPRQPIVILTGAGISRESGLHTFRDADGIWARVRIEDVATPEGFERDPERVQGFYNARRRGLL
EPEVQPNAAHHALARLEAAWPGGVLLVTQNIDDLHERAGSRNLIHMHGELMKVRCTACGSVTRRDHDVVTGEPCPACGSAGSLRPHVVWFGEMPLEMERI
QAALEGCGLFVSIGTSGNVYPAAGFVAEARAAGAMTLELNLEPSHGARLFAEGAYGPATSVVPAWVERMLAGLD-----
>tr|G0TUE3|G0TUE3_TRYVY Putative NAD dependent deacetylase OS=Trypanosoma vivax (strain Y486) GN=TVY486_0402430 PE=3 SV=1
-----------------------------------RSKQGRFVAVLTGAGISAESGIPTFRGKDRLWENHRVVDVACPAAYARNPQLVQQFYNQRRRALL
APSVKPNAAHLALAKLERQYDAGVVIITQNVDNLHERAGSKRIFHIHGELLKVRCSVTGEVFEIKEDVVHGTRCHCCGKTSTLRPHIVWFDEVPFYMDEI
QEIMKCTALFVAIGTSGNVYPAAGLATMAKSYGARTLEMNLEPGENCSDFDECVYGKASEIVPAWVERLLQSN------
>tr|C1AAZ7|C1AAZ7_GEMAT NAD-dependent deacetylase OS=Gemmatimonas aurantiaca (strain T-27 / DSM 14586 / JCM 11422 / NBRC 100505) GN=npdA PE=3 SV=1
-----------------------------------ALRAAEHVCVLTGAGISAESGIPTFREAQGLWAKFSPQELATPQAFASHPSRVWQWYAMRRAMV-
-RAAQPNPGHAALLSLALRV--ACTIVTQNVDDLHERSGVREPIRLHGSLMHIRCSQGCAGSVPAP-ATAEPKCPQCG--GLMRPDVVWFGEGLPPFGAA
REAAVACDVFLSVGTSNIVEPAASLPWISATHGATVIVVNPTMEGRKGPSILPIEGPAGVMLPRLIAEAFAGRR-----
>tr|A0A031GFC8|A0A031GFC8_MICLU NAD-dependent protein deacylase OS=Micrococcus luteus GN=cobB PE=3 SV=1
-----------------------------------ALAAAERPVVLSGAGMSAESGIPTFRDAQGLWERFSAEQLATEEAFLADPALVWSWYRWRARMV-
-RARRPIPGHDAVAAWQRRT--PLEVVTQNVDDLHERAGARVLAHLHGSLFEHRCAECGAPADVDPGLREAPACPACG-TGRIRPGVVWFGEMLPPWERA
YEALERCDLALVVGTSGLIQPAASLPFVALGAGVAVVEVNPVETELSGAVTHALRGSAGAVLPALVAGVWPGPS-----
>tr|A0A0D1PXK3|A0A0D1PXK3_9BRAD Contig98, whole genome shotgun sequence OS=Bradyrhizobium sp. UASWS1016 GN=QU42_02095 PE=3 SV=1
------------------------------------MATARSVVVLTGAGMSAESGVPTFRDAQGLWERFVPEQLATERAFRANPALVWTWYMWRWHLV-
-NGVTPNAGHNAIARWQQHLGAGLTVATQNVDDLHERGGASNVLHLHGSLGAFRCIDCHRATAFTPGNLLTVACQHCA-TGVLRPGVVWFGEALPAFERA
IDQLQTAELVVVIGSSGLVQPAASLPLIGRDAGAKLIEINPSTTELSQSADVHIASTAAVALPSLVAKMV---------
>tr|A0A0P9PZX4|A0A0P9PZX4_PSESX NAD-dependent protein deacylase OS=Pseudomonas syringae pv. daphniphylli GN=ALO73_01033 PE=4 SV=1
-----------------------------------DWGAARKVVFFTGAGISAESGIPTFRDKLGFWEKLDPEKLETARAFRENPQLVWGWYLWRRSQA-
-GQAQPNAAHLSISHLASTG--IVSVITQNIDDLHERAGSQNVVHLHGSLINPICFACKRTAVLTTDQWVEPRCTRCN--GKLRPGVVWFGEDLPAWKAA
LADVNNCDVLISVGTSGVVRPAADIPEIASTSGATVIHVNTADVCLGAPNELMLIGSAEQVLPALLETTHSS-------
>tr|G2PCN4|G2PCN4_STRVO NAD-dependent deacetylase OS=Streptomyces violaceusniger Tu 4113 GN=Strvi_2492 PE=4 SV=1
-----------------------------------AVTHRPLVAILSGAGISTDSGIPDYRGPQGLWRRPEAEKLVTYEYYMTDPEIRRSWQMRRDSET-
-LRARPNGAHEAVTRLERSG--VVRVITQNVDGLHQIAGMRKVLELHGTARAVLCTHCEARSGMEEAAGDPPACRECG--GILKSATVMFGESLDVLTEA
VAVAQACEIFIAVGTSLQVQPAASLAGLAAEHGARLIIVNAEPTPYDELADEVVREPISTALPAVLDRVAAGGG-----
>tr|V5SEZ1|V5SEZ1_9RHIZ Uncharacterized protein OS=Hyphomicrobium nitrativorans NL23 GN=W911_12630 PE=3 SV=1
------------------------------------AMKRASIVVLTGAGLSAESGVPTFRDKGGIWAQYDYREVATPEGFARNPVRLHEFYNLRRKAHA
D--VRANAAHHALATLEREHAGDVWVVTQNVDALHEEAGSRNLIHMHGELFRALCGACGTSVSCHEDLSLARACGEQG---FMRPDVVWFGEMPYHMERI
AELLAAADLFISIGTSGNVYPAAGFVAEARAAGAHTVELNLEPSEGQPLFAEAVYGRATEIVPAYVAKLLSE-------
>tr|A0A0A8K3H2|A0A0A8K3H2_9RHIZ NAD-dependent protein deacetylase of SIR2 family OS=Methyloceanibacter caenitepidi GN=GL4_1084 PE=3 SV=1
-------------------------------------MSFERIVILTGAGLSAESGLGTFRGKDGLWDAYNVEELATPEGFARNPTKVHDFYNMRRGWLA
-D-VRPNAAHFALAKLEREH-GEVLTVTQNIDPLHEDAG-SSLIHMHGELARALCAACGASRPWTEDLSLAPACGESG---YMRPDVVWFGEMPREMERI
YAALGACDLFVAIGTSGTVYPAAGFVAEAHRA-AHTVELNLEPSEGATLFAETHYGSATEIVPAYVESLLQG-------
>tr|V7FTR5|V7FTR5_9RHIZ NAD-dependent deacetylase OS=Mesorhizobium sp. LSHC420B00 GN=X759_02410 PE=3 SV=1
-------------------------------------MSKAKIVILTGAGISAESGVATFRDPDGVWAKYDLQDVATPQGFARDPVKVQDFYNMRRRQMG
-S-VEPNAAHAALAKLEQKF-GDVLVVTQNIDDLHERAG-RKLIHMHGELGHALCLSCGQSSTWADDIAAHPACGAKG---QLRPDVVWFGEMPYRMEEV
GEALTRCDLFVAIGTSGSVYPAAGFVEEARAA-AVTAELNLKCAGWASRFDEQMEGPATQVVPAFVERVLSG-------
>tr|A0A0D6JCF8|A0A0D6JCF8_9RHIZ Deacetylase of acetyl-CoA synthetase, NAD-dependent OS=Candidatus Filomicrobium marinum GN=cobB PE=3 SV=1
------------------------------------MTVYQRIVILTGAGLSAESGLSTFRDKDGIWARYDYRDVATPEGFARNPSLVYDFYNQRRRDGM
-G-VQPNAAHRALAKLEDAF-GDVVIVTQNIDGLHEAAG-RNLIHMHGQMAQALCALCNARSPWVEDLSADSACATPG---GMRPDVVWFGEMPYDLDRI
AAALSSCDLFISIGTSGNVYPAAGFVAAARDI-AHTVELNLEPSEGASLFAEHVHGPATEVVPAYVDKLLSV-------
>tr|A0A0H1AD01|A0A0H1AD01_9RHIZ NAD-dependent deacetylase OS=Mesorhizobium sp. LC103 GN=XW59_01110 PE=3 SV=1
------------------------------------SSPSPSLVILTGAGISAESGIDTFRDKDGIWSKIDYRDVATPEGFMRNPARVHDFYNRRRRRMK
G--IRPNAAHHALARLEAEWKGEFLLVTQNIDDLHESAGSKKLIHMHGELGGALCQACGARRRWPDDMSINPSCEATG---FMRPDVVWFGEMPYHMDRI
YRALGAAGTFISIGTSGNVYPAADFVVEARHADARTIELNLEPSEGVDVFHQAIHGRATEIVPAFVERLLAQ-------
>tr|A0A0J9H439|A0A0J9H439_9RHOB NAD-dependent protein deacetylase of SIR2 family OS=Candidatus Rhodobacter lobularis GN=AIOL_000619 PE=3 SV=1
---------------------------------------MASVVILTGAGVSAESGLGTFRD-DGLWTKYDLNDVATPEGFARDPALVHDFYNARRANCR
G--AAPNAAHRALARLQREH-GRVTLVTQNVDDLHERGGSDEVWHMHGALNGALCAACGHRWDAPEQMA-SPGCGAP----ATRPDVVWFGEMPYLMDEI
YARLEAADLFVSIGTSGNVYPAAGFVQVAAGAGAQTLELNLEPSEGASLFDAARHGPATEIVPQWVAEVLA--------
>tr|A0A0M7BCK4|A0A0M7BCK4_9RHOB NAD-dependent protein deacylase OS=Jannaschia seosinensis GN=cobB_1 PE=3 SV=1
---------------------------------------MKRIVVLSGAGLSAESGLGTFRDVGGLWSQYDLADVATPEGFARDPALVHAFYDARRANMA
G--ARPNAAHAALARLSGR--DDVTLVTQNIDDLLERAGARSVIHMHGELSRALCAVCGHRWDAPPVMEPAPACDAA----ATRPDVVWFGEMPYHMETI
ERALGDADLFVSIGTSGTVYPAAGFVEAARMAGAETLELNLEASGGR--FDAVREGPASVVVPDWVAEVLGD-------
>tr|Q2CCR0|Q2CCR0_OCEGH NAD-dependent deacetylase OS=Oceanicola granulosus (strain ATCC BAA-861 / DSM 15982 / KCTC 12143 / HTCC2516) GN=OG2516_08948 PE
--------------------------------------MQLRIVVLTGAGISAESGLGTFRDAGGLWARYAIEDVATPEAFARDPALVHDFYNMRRAEAA
R--ARPNPAHAALARLAASAH-EVTLVTQNVDGLHEAAGSP-ALHMHGRLSGALCAACGHRWAAPEAMSPEPACGAR----AARPDVVWFGEMPHGLEEI
EEALAGADLFAAIGTSGEVYPAAGFVEAA-RPGAHTVELNLAPSLRARAFRERRIGKASVVVPTWVDELLA--------
>tr|A0A0P7WIL8|A0A0P7WIL8_9RHOB NAD-dependent deacetylase OS=Rhodobacteraceae bacterium HLUCCA08 GN=npdA PE=4 SV=1
----------------------------------------MNIVILTGAGISAESGLGTFRDKGGLWETADWRDLATPEGFSRDPGLVHDFYNMRRARVR
A--ARPNAAHAALARLQADGRHAVTLVTQNVDDLHERAGAAGVIHMHGTHLVALCAACAHRWPAPDQMAPAPECRG-----TARPDVVWFGEQPYHMDMI
VSALAGCDLFVAIGTSGVVYPAAGFVEIATRTGADTLELNLEPGERASDFAAGRFGPATQVVPAWVDEMLA--------
>tr|A8LI11|A8LI11_DINSH NAD-dependent deacetylase OS=Dinoroseobacter shibae (strain DSM 16493 / NCIMB 14021 / DFL 12) GN=npdA PE=3 SV=1
--------------------------------------MPKRIVILSGAGLSAESGLGTFRDKDGLWTKYDLAEVATPEGFAANPALVHGFYNARRANCL
D--ARPNAAHAALAALQRQ--AEVTLVTQNVDDLLERAGARDVIHMHGQLNRALCAACGHRWDAPREMAPDPACARP----ATRPDIVWFGEIPYHMAMI
EAALAAAELFVSIGTSGEVYPAAGFVQEARAAGIPTLELNLEPSSGSALFTDARYGPATEIVPAWVAELGA--------
>tr|A3VL61|A3VL61_9RHOB NAD-dependent deacetylase OS=Maritimibacter alkaliphilus HTCC2654 GN=RB2654_17961 PE=3 SV=1
----------------------------------------MTILILTGAGISAESGLGTFRDKDGLWTKYDLNEVATPEGFARNPKHVQTFYNARRANCR
G--ATPNAAHVALGQLVSAR-EDVILVTQNVDDLHERGGATGVIHMHGELARALCAACDHRWDAPDEMSVDPACGTK----ATRPDVVWFGEMPYHMERI
YDAMAEVDLFVAIGTSGNVYPAAGFVTEAKQNGAETLELNLEPTDARGLFDAGRYGPASQVVPLWVDEVLGR-------
>tr|A0A0P7VXP5|A0A0P7VXP5_9RHOB NAD-dependent deacetylase OS=Rhodobacteraceae bacterium HLUCCO07 GN=npdA PE=4 SV=1
--------------------------------------MDDKIVILTGAGISAESGLGTFRDENGLWTRYDLEEVATPEGFARNPDFVHDFYNARRANCA
G--AEPNAAHAALARLEREY-GEVVIVTQNVDDLHERAGAARVIHMHGALSGALCAACGHRWPAPPAMQTAPACAAM----ATRPDVVWFGEIPYHMDAI
MGHLASCSRFAAIGTSGEVYPAAGFVQLATETGAHTVELNLEPSSVVSTFAETRYGPATKVVPGWVSDILAP-------
>tr|A0A058ZHF1|A0A058ZHF1_9RHOB NAD-dependent deacetylase OS=Actibacterium atlanticum GN=ATO10_14514 PE=3 SV=1
---------------------------------------MDKIVILTGAGVSAESGLGTFRDAGGVWTQYDLEEVATPEGFAKNPGLVHDFYNARRENCK
N--KAPNAAHDALARLEREF-GDLMLVTQNVDDLHERAGCQNVVHMHGELMRARCALCDHRYDAPLVMGVAPACERG----PTRPDIVWFGEMPFFMDDI
YVALSAADLFVSIGTSGSVYPAAGFVQIADAAGADTLELNLEPSLGISDFAQARQGPATQIVPEWVAEILG--------
>tr|A0A0P7WQM5|A0A0P7WQM5_9RHOB NAD-dependent deacetylase OS=Rhodobacteraceae bacterium HLUCCA12 GN=npdA PE=4 SV=1
---------------------------------------MTRIVILTGAGISAESGLGTFRDKDGLWTKYDLEEVATPQGFRRNPALVHDFYNARRANCA
A--ARPNAAHVALARLEAAMPDDVLIVTQNVDDLHRRAGSRNVLQMHGALMRATCHACRHTWPAPERMEPGPACNKT----ATRPDVVWFGEVPYHLDEI
GKALETASIFAAIGTSGQVWPAAGFAAAARQNGAHCVELNLEPSDATADFHDCRTGPATELVPHWVDELLAS-------
>tr|A0A0B3SF96|A0A0B3SF96_9RHOB NAD-dependent protein deacylase OS=Ponticoccus sp. UMTAT08 GN=cobB_1 PE=3 SV=1
--------------------------------------MTGKIVILTGAGLSAESGLGTFRDEDGLWAKHKIEDVATPEGFARNPSLVHDFYNARRRQSA
G--AAPNAAHEALARLQQYW-GEVILVTQNVDGLHESAGGE-AVHMHGTLAGALCAACGHRWTAPETMLPEPACAAP----ATRPDVVWFGEIPYHMDEI
AEHLQDCAIFAAIGTSGQVYPAAGFVVEAALAGAETVELNLERTEVSRAFTRHCMGKATEVVPPWVDSLLAR-------
>tr|X6KX95|X6KX95_9RHOB Contig12, whole genome shotgun sequence OS=Rhodobacteraceae bacterium PD-2 GN=P279_16745 PE=3 SV=1
---------------------------------------MDRIVVLTGAGLSAESGLGTFRDAGGLWAQHRIEDVATPEGFARNPALVHEFYNARRAQAA
A--AQPNAAHRALARLA--GRAPVTLITQNVDGLHEKAGAE-AIHMHGALSRALCAACGHGWEAPATMAPEPACAAC----ATRPDVVWFGEMPYHMDLI
ADRLAECTVFAAVGTSGQVYPAAGFVQEAAARGAHTVELNLESTDVSGAFDAHHTGPASRIVPEWVDRLLAG-------
>tr|A4WXI3|A4WXI3_RHOS5 Uncharacterized protein OS=Rhodobacter sphaeroides (strain ATCC 17025 / ATH 2.4.3) GN=Rsph17025_3213 PE=3 SV=1
---------------------------------------MDSIFILTGAGISAESGLGTFRDKDGLWTRYDLRRVATPEGFRDDPALVHDFYNMRRRNCL
E--ATPNAAHEALARLQRQRPGRVTLVTQNVDDLHERAGSPEVIHMHGELLGALCAACGHRWHAPERMAADPACARP----ATRPDIVWFGEIPYRMDEI
LERLSRATLFAVIGSSGEVYPAAGFVEEAAARGIATIEINLEPGSRRDLFDRGLHGPASETVPRWVEELLQA-------
>tr|A0A086YD31|A0A086YD31_9RHOB NAD-dependent deacetylase OS=Haematobacter massiliensis GN=CN97_07175 PE=3 SV=1
--------------------------------------MDMRIVILTGAGISAESGLRTFRDSDGLWEDHRIEDVATPEAFTRNPHLVQTFYNARRRTSR
A--AVPNLAHAALARLEAML-GEVMIVTQNVDDLHERAGSRNVLHMHGSLEGALCAACAHRWAAPAIMAVEPACGAP----AGRPDIVWFGEYPYHMEEI
WNALRKAEIFVAIGTSGNVYPAAAFVQDAARAGAYTIELNLEASATHSDFDETRQGLATEIVPSWVEELLKR-------
>tr|A0A0D6B4L4|A0A0D6B4L4_RHOSU NAD-dependent deacetylase OS=Rhodovulum sulfidophilum GN=NHU_02864 PE=3 SV=1
---------------------------------------MTKIVILTGAGISAESGLGTFRDVDGLWTRYDLNDVATPEGFARDPGLVMEFYNARRRNAA
E--AAPNPAHLALARLEAALPGSVRIVTQNVDDLHERAGSRAVWHMHGELARARCASCGAGWQAPAEMRVAPSCGVA----ATRPDIVWFGEMPYRMEEI
WEALRAADLFVSIGTSGSVYPAAAFVQDAARAGAETLELNLEPSEIAGDFDRGLHGPASEIVPVWVEEYLGA-------
>tr|K2PJK1|K2PJK1_9RHIZ Silent information regulator protein Sir2 OS=Nitratireductor indicus C115 GN=NA8A_15886 PE=3 SV=1
-------------------------------------MRFTSIVVLTGAGVSAESGIDTFRTKDGLWSKIDYRDVATPEGYAANPVLVHEFYNMRRRKIA
-T-VEPNDAHRALARLERGF-GDFLLVTQNVDDLHERAG-KKLIHMHGEHRKALCARCGSRSPWEGDMSVEPSCGAVG---HMRPDIVWFGEMPYQMDRI
YDALRLADLFISIGTSGNVYPAAQFVQEAGRN-AHTIELNLEPSETFDDFDEAIHGPAGKVVPEYVDWLLKL-------
>tr|A0A037ZJ66|A0A037ZJ66_9RHOB NAD-dependent deacetylase OS=Actibacterium mucosum KCTC 23349 GN=ACMU_10400 PE=3 SV=1
---------------------------------------MARIVILTGAGISAESGLGTFRDKGGVWTQYDLAEVATPEGFAADPAKVHNFYNMRRANAA
Q--AVPNAAHHALARLEAAMGDDLRIVTQNVDGLHEAAGSTRVWHMHGRLNRARCAACGATWDAPAVMATDPTCAAP----ATRPDIVWFGEMPMYMDQI
WDVLRGAELFVSIGTSGQVYPAAAFVQDADRAGAHTLELNLEASAVTSDFAEVRQGAATEIVPAWVDEELVR-------
>tr|A0A0L1KGB7|A0A0L1KGB7_9SPHN NAD-dependent protein deacetylase of SIR2 family OS=Erythrobacter citreus LAMA 915 GN=J121_2815 PE=3 SV=1
------------------------------------MTDMRNIVILTGAGISAESGIDTFRD-GGLWEQHRVEDVATPEGFARDPELVLRFYDMRREAIQ
T--KQPNAAHEALARLDANW-GELLIVTQNVDDLHERAGAGRVLHMHGTHLNAWCTACDVRTPWTGPLI-RPACDAR----SLRPDVVWFGEMPYEMGRI
YSALRRADLFVSIGTSGAVYPAAGFVEEARQRRVRTLELNLEASQGSRWFHETRQGPATKVVPQWVDEVLGG-------
>tr|A0A0N9V137|A0A0N9V137_SPHMC NAD-dependent deacetylase OS=Sphingopyxis macrogoltabida GN=AN936_22320 PE=4 SV=1
------------------------------------MKDIHNIVILTGAGVSAESGIDTFRD-GGLWEQHRVEDVATPEAFARDPALVQRFYDMRRAAIQ
T--KEPNAAHAALARLDAEW-GELLIVTQNVDDLHERAGAKRLLHMHGEHLKAWCTACDARSDWLGPLG-APACGTSG---HLRPDVVWFGEMPYHMEDI
YRALNRTDLFVSIGTSGAVYPAAGFVREARAAGARTLELNMEPSQGSHWFDEAHHGPATALVPGWVAEMLS--------
>tr|A0A095AQR0|A0A095AQR0_9SPHN NAD-dependent protein deacylase OS=Sphingopyxis sp. LC81 GN=cobB PE=3 SV=1
------------------------------------MSDINNIVILTGAGVSAESGIDTFRD-GGLWEQHRVEDVATPEAFARDPDLVLRFYDMRREAIQ
T--KAPNAAHEALARLDAAW-GELLIVTQNVDDLHERAGAKRLIHMHGEHLNAWCTACDTRVPWTGPLL-RSACGIVG---TLRPDIVWFGEMPYRMEDI
YHALNRADLFVSIGTSGAVYPAAGFVREARASGARTLELNMEPSQGSYWFDEARQGPATRLVPEWVEEILG--------
>tr|A0A095C355|A0A095C355_9SPHN NAD-dependent protein deacylase OS=Sphingopyxis sp. LC363 GN=cobB PE=3 SV=1
------------------------------------MSPIQNIVILTGAGVSAESGIDTFRD-GGLWEQHRVEDVATPEAFERDPDLVLRFYDMRREAIQ
T--KEPNAAHRALARLDAEW-GEFLIVTQNVDDLHERAGAKRLLHMHGEHLNAWCTGCDVRSPWTGPLL-RPACGAAG---SLRPDIVWFGEMPYRMEEI
YHALNRADLFVSIGTSGAVYPAAGFVREARAAGARTLELNMEPSQGSHWFDEARHGPATALVPAWVEAMLGG-------
>tr|Q1YGM2|Q1YGM2_AURMS NAD-dependent deacetylase, SIR2 family OS=Aurantimonas manganoxydans (strain ATCC BAA-1229 / DSM 21871 / SI85-9A1) GN=SI859A1_0
-------------------------------------MQFQSILILTGAGISAESGVDTFRDVGGIWSKVRLEDVATPEGFARDPAMVHDFYNQRRAGLA
-G-VKPNPAHHALARLEREF-GSVTVVTQNIDDLHERAG-RGVIHMHGELAKALCARCGTRGPSPDQLSTERQCGSLA---GMRPDVVWFGEMPYHMDMI
YDRLAAADLFVSIGTSGAVYPAAGFVEDARAN-SRTLELNLEPSAGTMLFSEARHGPASRLVPDFVDELLAR-------
>tr|A0A081KCD2|A0A081KCD2_9GAMM NAD-dependent deacetylase OS=Endozoicomonas elysicola GN=GV64_14635 PE=3 SV=1
------------------------------------SSPYSSIVVLTGAGISAESGIRTFRAGDGLWENHPVEDVATPEGYARNPSLVQRFYNDRRRQLN
-S-VEPNRAHQALAEFERQF-GSFLLVTQNVDDLHERAG-TRLIHMHGELLKVHCQDTEEVFHWDQDVTVDECCGVAG---NLRPHIVWFGEMPLQMDEI
YQALSNCDLFVSIGTSGNVYPAAGFVQEAAAA-AKTVELNLEPGNHGSLFDEQHYGPATEVVERFFSSLK---------
>tr|W8FYK1|W8FYK1_9GAMM Uncharacterized protein OS=Thalassolituus oleivorans R6-15 GN=R615_11385 PE=3 SV=1
--------------------------------------MSKRIVVLTGAGISAESGIMTFRDGGGLWENHRIEDVATPQGFARNPSLVQSFYNGRRQQLK
-S-VTPNPAHIALAEFEKNY-GEFMLVTQNVDDLHERAG-QSVIHMHGELKRVRCQLSGQVFHHDDDITPEPCCGA-Q---SLRPHIVWFGEMPLYMDEI
TQALSQCDLFISIGTSGHVYPAAGFVELARQS-AETIEINLEPSQRADAFHQAIHGQASIEVPHFFRSLLQN-------
>tr|A0A081NH19|A0A081NH19_9GAMM NAD-dependent deacetylase OS=Endozoicomonas numazuensis GN=GZ78_08650 PE=3 SV=1
------------------------------------MPRYQSIVVLTGAGISAESGIRTFRASDGLWENHPVEEVATPEGYYRNPALVQSFYNGRRQQLS
-E-VVCNDAHKALSDFEKAF-GDFLLVTQNVDDLHSRAG-QNLIHMHGELYKARCQDTEQVFDWHEDLTTQPCCKQAG---NLRPNIVWFGEMPLEMNRI
YEALSQCDLFVSIGTSGNVYPAAGFFAEAKAA-AETVELNLEPGSNASQFDRSLTGHATELVPDFFNALLG--------
>tr|W4HP85|W4HP85_9RHOB NAD-dependent deacetylase OS=Roseivivax atlanticus GN=ATO8_07291 PE=3 SV=1
--------------------------------------MADTIVILTGAGISAESGLGTFRDTDGLWSKVRIEDVATPEAFARDPARVQEFYNMRRTQAA
G--AAPNPAHHALARLQRDH-GRVVIVTQNVDGLHEAAGAT-VLHMHGALDRALCAACGHRWPAPAEMRPEPACDAP----AGRPDVVWFGEMPHHMEEI
AELLAAADLFVAIGTSGQVYPAAGFVQEARLAGVETLELNLAESDVSAAFDRHEIGPASEIVPDWVDRVLSG-------
>tr|X7EDA8|X7EDA8_9RHOB NAD-dependent deacetylase OS=Roseivivax halodurans JCM 10272 GN=OCH239_05360 PE=3 SV=1
--------------------------------------MDGKIVILTGAGISAESGLGTFRDEDGLWTKVPIEEVATPEAFARNPAKVHDFYNMRRVRAA
E--AQPNAAHHALTRLQTERP-ETVIVTQNVDALHERAGAR-VIHMHGELCRALCAACDHRWDAPPEMSPGPACGAP----KARPDIVWFGEMPYHMEEI
AGHLRAADLFVAIGTSGAVYPAAGFVEEARMAGAETLELNLNRSDVSAAFDAHALGPASEIVPAWVDEMLAR-------
>tr|X7F2Z0|X7F2Z0_9RHOB NAD-dependent deacetylase OS=Roseivivax isoporae LMG 25204 GN=RISW2_15340 PE=3 SV=1
--------------------------------------MAEKIVILTGAGISAESGLGTFRDADGLWSQVRIEDVATPEAFARDPARVHAFYNMRRAAAA
A--AAPNPAHHALARLQRDHPGEVVIVTQNVDDLHGRAGAE-VLHMHGALARALCASCGETWAAPPEMAPGPACERP----ATRPDVVWFGEMPHRLDDI
ADHLAACSLFAAIGTSGAVYPAAGFVREARAAGADTVELNLGASDVSPLFHRRLTGPASRVVPDWVDTLLAQ-------
>tr|A0A0M5IJR3|A0A0M5IJR3_SPHS1 NAD-dependent deacetylase OS=Sphingopyxis sp. (strain 113P3) GN=LH20_18040 PE=3 SV=1
------------------------------------MSSTRNIVILTGAGVSAESGINTFRD-GGLWEEHRVEDVATPEAFVRDPDLVHRFYDARRAAIQ
E--KAPNAAHEALARLDAAW-GELLIVTQNVDDLHERAGAKRLIHMHGEHLNAWCTACDQRSPWTGPLI-RPACGMAG---YLRPDVVWFGEMPYRMDEI
YRAINRADLFVSIGTSGAVYPAAGFVREARANGARTLELNLEPSEGSYWFDEARHGPATALVPAWVDEVLGG-------
>tr|I5BTI6|I5BTI6_9RHIZ NAD-dependent deacetylase OS=Nitratireductor aquibiodomus RA22 GN=A33O_17704 PE=3 SV=1
-------------------------------------MDYRRIVILTGAGVSAESGVDTFRDKNGLWSKIDYRDVATPEGFAANPALVHDFYNMRRRRIA
-E-LEPNDAHRALARLEREF-GEVLLVTQNIDDLHERAG-KNLIHMHGEHRSALCTHCGDRSPWEGDMSLEPACATVG---HLRPDVVWFGEMPYQMERI
YDALRAADLFISIGTSGNVYPAAQFVQEAGRA-AHTIELNLEPSDTFDDFDEAVHGPASRVVPSYVDMLLKS-------
>tr|N9W977|N9W977_9SPHN NAD-dependent deacetylase OS=Sphingopyxis sp. MC1 GN=EBMC1_15669 PE=3 SV=1
------------------------------------MSGVHNIVILTGAGVSAESGIDTFRD-GGLWEQHRVEDVATPEAFVRDPDLVHRFYDARRAAIQ
T--KQPNAAHAALARLDAHW-GELLIVTQNVDDLHERAGAKRLIHMHGEHLNAWCTACDRRSPWTGTLI-RPACGMVG---YLRPDVVWFGEMPYRMDDI
YRAINRADLFVSIGTSGAVYPAAGFVREARQAGARTLELNMEPSQGSYWFDEARQGPATQLVPQWVDQLLGF-------
>tr|A0A0Q7YRV8|A0A0Q7YRV8_9SPHN NAD-dependent deacylase OS=Sphingopyxis sp. Root1497 GN=ASD67_06400 PE=4 SV=1
------------------------------------MKEIQNIVILTGAGVSAESGIDTFRD-GGLWEQHRVEDVATPEAFVRDPDLVHRFYDARREAIQ
T--KVPNAAHDALARLDAAW-GELLIVTQNVDDLHERAGAKRLIHMHGEHLNAWCTGCDTRSRWTGPLI-RPGCGVAG---LLRPDVVWFGEMPYYMDAI
YHALNRADLFVSIGTSGAVYPAAGFVREARASGARTLELNMEPSQGSHWFGEARHGPASVLVPAWVEEMLGA-------
>tr|A0A0L6J8C5|A0A0L6J8C5_9RHIZ NAD-dependent deacetylase OS=Methylobacterium sp. ARG-1 GN=AKJ13_14845 PE=3 SV=1
------------------------------------MGDPNNIFVLTGAGVSAESGLGTFRDRGGIWARFDPMKLATPEAYAADPDTVLDFYDHRRRGV-
-VAAEPNAAHVALARAEARLAGHLFLCTQNVDDLHERAGSRAVVHMHGELLKARCTACGTVTPWRDDLDRDPACGGVG---RMRPDVVWFGEMPMHLDAI
EAALAAADLFVAVGTSGAVYPAAGYVRKARARNIPTCEINLEPSDNADAFDDARYGPASTALPRFLADFGL--------
>tr|M7Z0A1|M7Z0A1_9RHIZ Silent information regulator protein Sir2 OS=Methylobacterium mesophilicum SR1.6/6 GN=MmSR116_3166 PE=3 SV=1
------------------------------------ADSPRTIFVLTGAGVSAESGLGTFRDRGGIWARFDPMKLATPEAYAADPDTVLDFYDHRRRGL-
-IAAVPNAAHGALARAEARLDGRLFLCTQNVDDLHERAGSRSVTHMHGELLKARCCACGAVIPWRADLGRAPACGTPA---RMRPDVVWFGEMPMHLDAI
EAALAEADLFVAVGTSGAVYPAAGYVRQARSLGIPTCEINLEPSDNADAFDAAHYGPASEALPRYLADLGL--------
>tr|A0A0P7J677|A0A0P7J677_9RHOB NAD-dependent deacetylase OS=Aliiroseovarius crassostreae GN=AKJ29_13785 PE=4 SV=1
------------------------------------TTEFKNIVILTGAGVSAESGLGTFRDKGGIWTRYDLQEVATPEGFAKNPSLVHEFYNARRANC-
-LEASHNAAHTALARLQAR--GRVSLITQNIDDLHERGGAVDVIHMHGELTRALCATCGHRWAAPREMDPAPNCHA-P---TTRPDIVWFGEIPYQMERI
LTPLSEADLFVALGTSGTVYPAAGFVGEARGMGIPTLEINLERSDGSGVFDHGIYGPASRAVPEWVQEILDE-------
>tr|A0A0F4RLH4|A0A0F4RLH4_9RHOB NAD-dependent deacetylase OS=Loktanella sp. S4079 GN=TW80_01460 PE=3 SV=1
----------------------------------------MKIAILTGAGLSAESGLGTFRDKGGIWTKYDLTQVATPEGFAADPALVHEFYNARRANC-
-VESEPNAAHFALGELQSD--HEVTIITQNIDDLHERGGAKDVIHMHGQLLRALCANCGERWDAPIIMTPTPRCSA-P---QTRPDVVWFGEIPYAMETI
QQKVSESDLFVAIGTSATVYPAAGLVQLARGE---TRELNLAPTDAAGAFDSGRYGPATSIVPEWVQSL----------
>tr|A0A0D1D6J0|A0A0D1D6J0_9RHOB CobB protein OS=Jannaschia aquimarina GN=cobB PE=3 SV=1
---------------------------------------MDRIVVLSGAGLSAESGLGTFRDMGGIWTRYDLSEVATPEGFAADPAKVHDFYNARRANMA
G--AAPNAAHDALARLSGR--ADVTLVTQNIDDLLERAGASGVIHMHGELSRALCHACRARWDAPASMAPGPACAAP----ATRPDVVWFGEVPYHMERI
EAALADADLFVSIGTSGQVYPAAGFVEMARLSGARTLELNLEASGGR--FDEVREGPATEVVPTWVAGLIGD-------
>tr|W8SNR4|W8SNR4_9RHOB NAD-dependent protein deacetylase of SIR2 family OS=Roseibacterium elongatum DSM 19469 GN=roselon_01814 PE=3 SV=1
---------------------------------------MERIVILTGAGVSAESGLGTFRDKDGLWTRYDLSEVATPEGYARNPRLVLDFYNARRANAL
E--ASPNAAHAALARLQAGFPGEVLLVTQNIDNLHERGGSGAVVHMHGEITRALCAACGHRWDAPRVMDPAPACGTP----ATRPDIVWFGEMPYHMERI
LPALGAADLFVAIGTSGEVYPAAGFVEIAQEAGAETLEINLDPAPAPGRFDRMIAGKATEAVPAWVAEVLGA-------
>tr|A0A0P8C464|A0A0P8C464_9RHOB NAD-dependent deacetylase OS=Rhodobacteraceae bacterium HLUCCO18 GN=npdA PE=4 SV=1
---------------------------------------MGGIVILTGAGVSAESGLGTFRDKGGLWTRYDLTEVATPEGFARNPRLVHDFYNARRANAL
D--SSPNAAHQALAQLTTRYTGEVLLVTQNIDDLHERAGATGVVHMHGEITRALCAVCETRWDAPRVMDPDPSCAAR----ATRPDIVWFGEMPYHMDRI
VTALEAADLFVAIGTSGEVYPAAGFVDIAAEAGAETLEINLEPTPAPGRFDRVLTGPAAVAVPAWVETVLAE-------
>tr|A0A0M6XLJ8|A0A0M6XLJ8_9RHOB NAD-dependent protein deacylase OS=Jannaschia rubra GN=cobB_1 PE=3 SV=1
------------------------------------AASSARIVVLSGAGLSAESGLGTFRDAGGLWARYDLEEVATPQGFARDPALVHDFYNARRANMT
A--SAPNAAHEALARLSRR--DGVTLVTQNIDDLLERAGARGVVHMHGDLSRALCHACGARWDAPAVMSPEPDCGAA----ATRPDVVWFGEMPYRMEEI
ETALAAADLFVSVGTSGTVYPAAGFAALARAAGARTLELNLDPSGGD--FDEVRTGPATQLVPGWVDEVMG--------
>tr|A0A0C1X6S5|A0A0C1X6S5_9CYAN NAD-dependent deacetylase OS=Scytonema millei VB511283 GN=QH73_08440 PE=3 SV=1
--------------------------------------MRPSLVILTGAGISAESGLGTFRDTDGVWSKFDWRQLATPEGFANDPVAVHGFYNARRQGL-
-VAAQPHAAHTALAELEAAWAGDFLLVTQNIDDLHERAGSRALIHMHGELFKARCGACETVTECRTDLSIAAACGREG---QMRPHVVWFGEIPLEMEEI
FSALETATHFAAIGTSGTVWPAAGFAEAAKAAGARTYEMSLEAGESGHFFDVTDYGPASETVPRWAKAMMDE-------
>tr|J7QRS5|J7QRS5_METSZ Silent information regulator protein Sir2 OS=Methylocystis sp. (strain SC2) GN=BN69_2802 PE=3 SV=1
----------------------------------------MNLFILTGAGVSAESGLGVFRGTGALWKRYDPMQLATPEAFMRDPALVHEFYNARRRNL-
-IAAASNAAHIALARLEAGLQDSMTLVTQNIDDLHERAGSKRVIHMHGELLKARCASCGAVRDCREELSTD--CGCDG---ALRPHVVWFGETPLYMEEI
YAALERADRFVAIGTSGAVYPAAGFVREARARGLRCCEVNLEPSENAAQFDERRYGRASEIVPSWVEEILAR-------
>tr|C7CKA1|C7CKA1_METED NAD-dependent protein deacetylase, regulatory protein SIR2 family OS=Methylobacterium extorquens (strain DSM 5838 / DM4) GN=cob
------------------------------------RRAMTNIFVLTGAGISAESGLGTFRDTDGAWARFDPMRLATPEGFAADPVLVHDFYNHRRRDA-
-RAAAPNPAHAALARLEAGLAGRLFLCTQNIDDLHERAGSRHVVHMHGALLKARCTACVTDTVWHEDLTVEPHCGHSG---EMRPDVVWFGEMPHHLEAI
DEALAEADLFVAIGTSGAVYPAAGYVAQARAFGIPTLALTLEAADNAGLFEATRLGRASETVPAFVEEVLNG-------
>tr|A0A0F9UGE0|A0A0F9UGE0_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_0268160 PE=3 SV=1
------------------------------------MRRPGSIVILTGAGISAESGVDTFRDEGGIWSRVKLEDVATPEGFARDPAMVHAFYNARRAGLA
-A-VEPNAAHHALAKLERVH-GAVTLVTQNIDDLHERAG-RNIVHMHGELTKAFCAACGTHSLADGDLSADTACGHAG---RMRPDVVWFGEIPYHMDDI
YKRLLAADLFVSIGTSGAVYPAAGFVAEARAA-IRTLELNLDPSDGTPLFDEARHGKASVLVPAFVTDILAG-------
>tr|Q0FXE2|Q0FXE2_9RHIZ NAD-dependent deacetylase OS=Fulvimarina pelagi HTCC2506 GN=FP2506_13194 PE=3 SV=1
------------------------------------FDGPKSIFVLTGAGVSAESGVATYRDQGGLWSKVRLEDVATPEAFARDPERVQAFYNARRAGLN
G--ISPNPAHEALARLERE--GTLTLVTQNIDDLHERGGSENVIHMHGRLRRSLCAICGDTREHHSDLHVTEACGETG---TLRPDVVWFGEMPHHMELI
FERLEQADLFVSIGTSGAVYPAAGFVSEAGRLGIRTLELNLEPSDGSFQFDEARHGPASKLVPAFVEEVLSG-------
>tr|B1Z7A2|B1Z7A2_METPB Silent information regulator protein Sir2 OS=Methylobacterium populi (strain ATCC BAA-705 / NCIMB 13946 / BJ001) GN=Mpop_2173 P
------------------------------------MPIPNTIFVLTGAGISAESGLGTFRDTDGVWARFDPMRLATPEGFAADPVLVHDFYNHRRRDT-
-RAASPNPAHAALARLEAGLEGQLFLCTQNIDDLHERAGSRHVVHMHGELLRARCTACGTEPVWHEDLTVAPDCGHGG---GMRPDVVWFGEMPKHLEAI
DEALSEADLFVAIGTSGAVYPAAGYVAQARAFGIPTLALTLEAADNAGMFEATRLGPASATVPAFVDEILSG-------
>tr|A0A0Q1A3E2|A0A0Q1A3E2_9BACT NAD-dependent deacetylase OS=Candidatus Cloacimonas sp. SDB GN=APR54_03965 PE=4 SV=1
------------------------------------LNPKSQIVVLTGAGVSAESGLKTFRDNNGLWENHRVEDVATPEAFRQFPELVWKFYKDRYFQL-
-AQVKPNPAHVALVELENFL-DNFNLITQNVDGLHFKAGNKNVIEMHGSLYECFCSDCNNRFL-MKDIDLDPVCSKCRG--YLRPDIVWFGEIPYHLNRI
QQIMSKLDLFLVIGTSGIVYPAAQLLPIAKSCGAHTVGINLEEPANLLYLDDFYKGLSGEILPDLVKQWIGK-------
>tr|B0VHF0|B0VHF0_CLOAI NAD-dependent deacetylase (Regulatory protein SIR2 homolog) OS=Cloacimonas acidaminovorans (strain Evry) GN=npdA PE=3 SV=1
------------------------------------FTPDTNVLVLTGAGISAESGIRTFRDSGGLWENHRVEDVATPEAFNSNPVKVWEFYRQRYQDS-
-ISSKPNPAHLALVKLEQFL-DNFLLVTQNVDCLHIKAGSKRVLEMHGSLANCICTKCHSKLA-IKDIDLTPLCPFCNG--ILRPDIVWFGEIPHYLNII
DDALRKCSVFIIVGTSGVVYPAAGFVLTAKLMGAKTIAINLGKPDNLAYIDEFYQGKSGDILPGLVAMWIGE-------
>tr|A0A0D6P4A5|A0A0D6P4A5_9PROT NAD dependent deacetylase OS=Acidisphaera rubrifaciens HS-AP3 GN=Asru_0105_03 PE=3 SV=1
------------------------------------KTGAPNIVILTGAGISRESGLATFRDPDGIWQQVRIEDVATPEAYRRDPERVQAFYNARRAQLA
D--VAPNAAHLALAELDRRW-GELLLVTQNVDDLHDRAGSRRLLHMHGELRRAWCRACDATHPWDEDLGMAPACATMG---RMRPHIVWFGEMPLHMDAI
EAALARCDLFVSIGTSGNVYPAAGFVAEV-RGRAETVELNLEPSEGTHLVDRAVHGPATRIVPDFVADLLAR-------
>tr|A0A0F2REU5|A0A0F2REU5_9RHOB NAD-dependent deacetylase OS=Hyphomonas sp. BRH_c22 GN=VR74_10040 PE=3 SV=1
------------------------------------AYAQRGVVVLTGAGISAESGLGTFRDVDGIWTKYPLEDLATPEGFARNPEFVQGFYNARRAQLK
T--SRPNAAHLALSELEAALARRFTLITQNVDHLHEQAG-QNVLHMHGELLKVRCEACRGVVRWPDDIGVRPTCEAVG---LMRPHVVWFGEMPLYMDEI
ETELARADLFVSIGTSGNVYPAAGFVQLARRAGARTLELNLEPSDGASFFDEARYGKASELVPDWASEIMRR-------
>tr|R0E070|R0E070_CAUVI NAD-dependent protein deacetylase, SIR2 family OS=Caulobacter crescentus OR37 GN=OR37_03990 PE=3 SV=1
----------------------------------------MKIFVLTGAGVSAESGLGTFRDKDGVWTKYDLETVATPEGFARNPVLVRDFYNARRANLM
D--AAPNAAHFALARLEAELADELWLCTQNVDDLHEKAGSRRVVHMHGELAVTRCHYCQATCPDRGALTAEGACGRAG---GARPHVVWFGEMPLHMDEI
EDALAEADLFVSIGTSGSVYPAAGFVTQARAMGIATCEINLEPSANAYVFDEKRYGPASRIVPAWVQDVLGA-------
>tr|F8AAG6|F8AAG6_THEID Silent information regulator protein Sir2 OS=Thermodesulfatator indicus (strain DSM 15286 / JCM 11887 / CIR29812) GN=Thein_1525
------------------------------------LNQISKIVILTGAGISAESGIQTFRDKGGLWEKYSLEEVATPQGFRKNPRFVHEFYNQRRRDLF
-K-VKPNPAHYALARLEQEF-GEVLLVTQNVDDLHERAG-RNLLHMHGELLKVRCEACNVILKEEGEIFPEPKCGRQG---TLRPHVVWFGEMPFYLDEI
YKALKECDLFVAIGTSGTVYPAAGFVMIAREC-AWCVELNLEPSTVADYFHEHHYGPASEVVPVWVDKILKR-------
>tr|A0A059FNQ4|A0A059FNQ4_9RHOB Uncharacterized protein OS=Hyphomonas johnsonii MHS-2 GN=HJO_09464 PE=3 SV=1
------------------------------------ANAARAVVVLTGAGISAESGLGTFRDVDGIWTKHPLEDLATPEGFARNPDFVQGFYNARRAQLK
-E-SEPNAAHLALARLEAALAHSFTLITQNVDNLHQAAG-QNVLHMHGELLKVRCGGCNAVVRWPGDISTAPCCEATG---LMRPHVVWFGEMPLHMDEI
ERAIDKASLFVSIGTSGNVYPAAGYVRMARMA-ARTVELNLEPSEGASLFQDTRYGPASEVVPAWVDEVMAT-------
>tr|A0A062UIG4|A0A062UIG4_9RHOB Uncharacterized protein OS=Hyphomonas chukchiensis GN=HY30_04900 PE=3 SV=1
------------------------------------ANAPRGIVVLTGAGVSAESGLGTFRDVDGIWTKYPLEDLATPEGFARNPDFVQGFYNDRRAQLK
T--SEPNAAHVALARLEAALARRFTLVTQNVDHLHETAG-QNVLHMHGELLKVRCQACGSVVRWPDDLTSKPVCEATG---LMRPHVVWFGEMPLYMDEI
EVELSRADLFVSIGTSGNVYPAAGFVQLARRAGARTLELNLEPSDGATFFDEARYGKASDVVPGWANDIMKW-------
>tr|A0A0B4B4I4|A0A0B4B4I4_9RHOB NAD-dependent deacetylase OS=Leisingera sp. ANG-Vp GN=RA20_20090 PE=3 SV=1
------------------------------------GKSAQKIVILTGAGISAESGLGTFRDEGGLWAQHRIEDVATPEGFARDPGLVHGFYNARRAQAA
G--AQPNAAHQALARLQAEH-GEVVIVTQNVDGLHEAGGASRVLHMHGTLAGALCAACGHRWVAPMEMHPGPACAAP----QGRPDVVWFGEMPYFMEEI
YAHLAAADLFAAIGTSGEVYPAAAFVDEAHLAGAHTVELNLEPSATASRFSERRFGPASETVPAWVAELLRS-------
>tr|A0A0H4KSK8|A0A0H4KSK8_9RHOB NAD-dependent protein deacetylase, SIR2 family OS=Marinovum algicola DG 898 GN=MALG_00826 PE=3 SV=1
---------------------------------------MGRIVILTGAGISAESGLGTFRDEGGLWARHRIEDVATPEGFARDPALVHRFYNIRRAQAA
A--ARPNAAHAALARLEAESSDVVTLVTQNVDDLHRRAGSHHVLQMHGRLAGALCDVCGHQWEAPPEMDEEPACHRA----AARPDVVWFGEYPHFMEEI
AALLAEARIFAAIGTSGQVYPAAAFVEDARAAGAETVELSLEPTAVSHLFDHCHSGPATETVPRWVESLLG--------
>tr|A0A0P1GQH4|A0A0P1GQH4_9RHOB NAD-dependent protein deacylase OS=Tropicibacter multivorans GN=cobB_2 PE=4 SV=1
---------------------------------------MSKIVILTGAGISAESGLGTFRD-GGLWAQHRIEDVATPEGFARDPDLVHDFYNARRQQAA
T--AQPNAAHIALARLERDY-GDVVIVTQNVDSLHEAAGSTAVLHMHGRLNSALCYGCGHRWDAPPEMG-GPACGAA----KTRPDVVWFGEIPYFMEEI
AHHLAAATVFASIGTSGQVYPAANFVQEARAFGAATVELNLEPSEISRAFDTRRFGPATEVVPDWVHSLLA--------
>tr|A0A0L6CVR0|A0A0L6CVR0_9RHOB NAD-dependent protein deacylase OS=Roseovarius tolerans GN=cobB_1 PE=3 SV=1
---------------------------------------MQKIVILTGAGISAESGLGTFRDVGGIWQRYRIEDVATPEAFARDADLVHGFYNARRVQAA
E--ARPNAAHRALARLQAEH-GEVVIVTQNVDGLHEAGGARDVIHMHGELARALCAACGGRWEAAAQMSVRPDCGAC----ACRPDVVWFGEMPYRMEEI
LSHLAGADIFAAIGTSGQVYPAAGFAQEAALAGARCVEINLEPSAVAGDFDEVRQGRASEVVPLWVAEILGG-------
>tr|A0A0A0EDV1|A0A0A0EDV1_9RHOB NAD-dependent deacetylase OS=Pseudooceanicola atlanticus GN=ATO9_10855 PE=3 SV=1
---------------------------------------MERIVILTGAGISAESGMGTFRGAGGLWNDRRVEDVATPEGFARDPAMVQDFYNQRRQKAR
Q--VAPNAAHEALARLQRDY-GEVTLITQNVDGLHEAGGSPSVIHMHGRLDGALCAACDHRWDAPEVMEVAPACGAG----AGRPDVVWFGEMPYFMDEI
FEALSRCTLFAAIGTSGQVYPAAGFVQEAFRAGAHTVEINLEPSAVVSDFAETRFGPATQTVPAWVADVLGG-------
>tr|A3TTC1|A3TTC1_OCEBH NAD-dependent deacetylase OS=Oceanicola batsensis (strain ATCC BAA-863 / DSM 15984 / HTCC2597) GN=OB2597_06430 PE=3 SV=1
---------------------------------------MDNIVILTGAGISTESGMGTFRGAGGLWENRRVEDVATPEGFARDPEMVHRFYNMRRQKAA
S--VRPNAAHEALARLQREH-GKVTLVTQNVDALHEAGGSDSVIHMHGRLAGALCAACDHRWEAPDEMHPGPACAAP----HARPDVVWFGEMPYHMEEI
FDALSTCTLFAAIGTSGQVYPAAGFVQEAFRAGAHTVEINLEPSAVVSDFAETRFGPATQTVPAWVDEVLGR-------
>tr|A0A073J2F6|A0A073J2F6_9RHOB NAD-dependent deacetylase OS=Sulfitobacter pseudonitzschiae GN=SUH3_17940 PE=3 SV=1
---------------------------------------MPKIVILTGAGISAESGLGTFRDEGGLWAQHRIEDVATPEGFARNPQLVVDFYNARRAQAA
-E-ASPNAAHVALAQLEAAM-GDVLIVTQNVDGLHEKAG-SNVLHMHGQLDSALCAACDHRWEATLKMTVGPACYQP----TARPDIVWFGEIPYYMEEI
EMRLSEADIFAAIGTSGNVYPAAGFVQAAAAY-ALTVELNLEPSMVVSQFDETHFGPASETVPKWVEGLLKA-------
>tr|A0A0P1FCV1|A0A0P1FCV1_THAGE NAD-dependent protein deacylase OS=Thalassobius gelatinovorus GN=cobB_2 PE=4 SV=1
---------------------------------------MEKIVILTGAGISAESGLGTFRDEGGLWAQHRIEDVATPEGFARNPQLVHDFYNARRLQAT
R--SLPNSAHTALALLEAEH-AQVIIITQNVDGLHEAAGSRTVLHMHGRLAGALCAKCGHRWAAPDAMRPDPACSTP----ATRPDIVWFGEIPYHMGEI
WDHLRDADLFAAIGTSGEVYPAAAFVQDADRHGAHTVELNLEPSSVVSDFSETHFGKATETVPLWVKNLLNG-------
>tr|A0A0P1E1V3|A0A0P1E1V3_9RHOB NAD-dependent protein deacylase OS=Ruegeria atlantica GN=cobB_1 PE=4 SV=1
---------------------------------------MEKIVILTGAGISAESGLGTFRDEGGLWAQHRIEDVATPEGFARDPALVHRFYNARRVQAA
E--AQPNAAHDALARLQRDW-SEVVIITQNVDNLHEAGGAQGVIHMHGTLAGALCAACGHRWTAPPEMAVGPACAAP----TARPDVVWFGEMPYHMDAI
YDHLAGASIFAAIGTSGQVYPAAAFVHEAMMSGARTVELNLEPSTGASSFDEVILGPATEAVPRWVDQILSS-------
>tr|A0A0P1ICR7|A0A0P1ICR7_9RHOB NAD-dependent protein deacylase OS=Ruegeria sp. CECT 5091 GN=cobB_1 PE=4 SV=1
---------------------------------------MEKIVILTGAGISAESGLGTFRDEGGLWAQHRIEDVATPEGFARDPALVHQFYNARRMQAA
K--AQPNAAHTALARLQKDF-GEVVIVTQNVDSLHEASGAERVIHMHGTLAGALCRACNHRWASPPEMAVGPACAAP----TARPDVVWFGEMPYHMDAI
YDHLSQATLFAAIGTSGQVYPAAAFVHEALQSGARTVELNLEPSTGASSFDKVILGPATETVPRWVNGFFSP-------
>tr|A0A0P1EUW7|A0A0P1EUW7_9RHOB NAD-dependent protein deacylase OS=Shimia marina GN=cobB_2 PE=4 SV=1
--------------------------------------MADNIVILTGAGISAESGLGTFRDEGGLWAQHAIEDVATPEGFARNPELVHAFYNARRKQSA
Q--AAPNAAHKALADLEKTH-GNVLIVTQNVDGLHEKAGSQNVLHMHGALAGALCHSCGHRWRAPVDMRPDPACTAP----ATRPDVVWFGEIPYYMEQI
SDALTQADLFVSIGTSGEVYPAANFVAEADYHGAHTVELNLEPSSGVSRFAEVHLGPATEIVPAWVQQELLR-------
>tr|A0A0P1I9C1|A0A0P1I9C1_9RHOB NAD-dependent protein deacylase OS=Phaeobacter sp. CECT 7735 GN=cobB_2 PE=4 SV=1
-------------------------------------MSNDKIVILTGAGISAESGLGTFRDEDGLWAQHRIEDVATPEGFHRDPDLVHAFYNARRAQSA
E--AKPNAAHDALAKLERDH-GEVLIVTQNVDGLHEIAGSTNVLHMHGALNGALCASCDSRWPAPLVMHKTPQCGRA----TTRPDIVWFGEMPYYMDEI
WGHLASADSFVAIGTSGEVYPAAAFVQEADRGGAHTIELNLAPSSRVSDFAETCFGPATQIVPQWVAQELSR-------
>tr|Q5LUS5|Q5LUS5_RUEPO CobB OS=Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) GN=SPO0978 PE=3 SV=1
---------------------------------------MRKIVILTGAGISAESGLGTFRDADGIWTKYPLEDVATPEGFARDPELVHTFYNARRVQAA
A--ARPNAAHTALARLQRDW-GEVVIVTQNVDALHEAGGASDVIHMHGTLAGALCAICGHRWLAPETMDTTPACARP----AARPGVVWFGEMPYFMDAI
YDHLASADLFAAIGTSGQVYPAAGFVQEATACGARTVELNLDPSAVVSNFDETRFGPASRIVPQWVCDLLDQ-------
>tr|S9QVH0|S9QVH0_9RHOB NAD-dependent protein deacetylase of SIR2 family OS=Salipiger mucosus DSM 16094 GN=Salmuc_02802 PE=3 SV=1
------------------------------------MARAERILVLTGAGISAESGLGTFRDEGGLWAQHDIRDVATPEGFARDPALVQGFYNARRLQAA
G--AAPNPAHVALARLQRDW-GEVTIVTQNVDALHERAGAE-VIHMHGELSRALCVACEHRWDAPPEMAPQPACGKP----AARPDVVWFGEMPYHMDLI
LEHLERCDRFAAIGTSGQVHPAAGFVQEATLAGAATIELNLESSEVSRIFHERRAGPATETVPAWVETLLAS-------
>tr|A0A0C1JJ14|A0A0C1JJ14_9RHOB NAD-dependent deacetylase OS=Ruegeria sp. ANG-R GN=RA27_08755 PE=3 SV=1
---------------------------------------MEKIVILTGAGISAESGLGTFRDEGGLWAQHRIEDVATPEGFARNPALVHRFYNARRVQAA
K--AQPNAAHKALARLQKDW-GEVVIVTQNVDGLHEAGGAENVIHMHGVLAGALCATCGHRWPSPPEMEVGPACRSP----TARPDVVWFGEMPYQMDEI
YDHLAGAALFAAIGTSGQVYPAAAFVHEAQAAGARTVELNLAPSAGVSSFDETRLGPATGTVPRWVEELLGE-------
>tr|A4EXL1|A4EXL1_9RHOB NAD-dependent deacetylase OS=Roseobacter sp. SK209-2-6 GN=RSK20926_14776 PE=3 SV=1
------------------------------------QAKREKIVILTGAGISAESGLGTFRDEGGLWAQHAIEDVATPEGFARNPRLVHDFYNARRIQAA
E--AKANKAHQALAQLQEHF-GEVVIVTQNVDSLHEKGGARNVIHMHGVLEGALCATCDHRWPAPDEMEPEPHSSAP----SARPDIVWFGEIPYAMEEI
EAHLSEASLFVAIGTSAQVYPAAGFVEAARSFGAETLEINLEPSDLANRFHSHRFGPATETVPEWVAALLT--------
>tr|A0A0F4RTX9|A0A0F4RTX9_9RHOB NAD-dependent deacetylase OS=Ruegeria mobilis GN=TW79_16265 PE=3 SV=1
---------------------------------------MSKIVILTGAGISAESGLGTFRDEGGLWSQHRIEDVATPEGFARDPELVHRFYSARRQQAA
E--AQPNAAHLALAQLEQHW-GEVVIVTQNVDGLHEAAGARNVLHMHGTLGGALCAACAHQWQAPMEMTLAPACGAQ----QARPDVVWFGEIPYHMEEI
ISHLEEADLFASIGTSGQVYPAASFVQEAAANGADTVELNLEPSEISRAFGERHFGPATEIVPKWVEGLLTG-------
>tr|B6B908|B6B908_9RHOB NAD-dependent deacetylase OS=Rhodobacterales bacterium Y4I GN=RBY4I_1517 PE=3 SV=1
------------------------------------MEKSAKIVILTGAGISAESGLGTFRDEGGLWAQHRIEDVATPEGFARNPDLVHGFYNARRAQAA
G--ADPNPAHRALARLQAEH-GEVVIVTQNVDALHEAGGAAQVLHMHGTLAGALCAACNHRWAAPLEMQTGPACAAP----AGRPDVVWFGEMPYFMEEI
YAHLAEADLFAAIGTSGEVYPAAAFVDEAHLAGAHTVELNLAPSAAASRFAERRFGPASETVPAWVAELLGP-------
>tr|B9NPH4|B9NPH4_9RHOB NAD-dependent deacetylase OS=Rhodobacteraceae bacterium KLH11 GN=RKLH11_2697 PE=3 SV=1
---------------------------------------MEKIVILTGAGISAESGLGTFRDEGGLWAQHRIEDVATPEGFARNPALVHGFYNARRGQAA
K--AQPNAAHQALARLQKNW-GEVILVTQNVDGLHEAGGAEPVIHMHGTLAGALCGACGHRWASPPEMEVGPACQQP----TARPDVVWFGEMPYFMDEI
YDHLIEATLFASIGTSGQVYPAAGFVQEARAVGAKTVELNLEPSAGGSIFDEVHLGPASEVVPRWVDTLLAG-------
>tr|A0A0C1GNT4|A0A0C1GNT4_9RHOB NAD-dependent deacetylase OS=Ruegeria sp. ANG-S4 GN=RA28_19435 PE=3 SV=1
---------------------------------------MGKIVILTGAGISAESGLGTFRDEGGLWAQHRIEDVATPEGFARNPALVHRFYNARRVQAA
G--ADANAAHRALARLQREW-DDVILVTQNVDSLHEAGGARDVIHMHGTLAGALCSTCQHRWVSEPEMTPAPACGQR----SVRPDVVWFGEMPYFMDEI
YDHLANAQIFAAIGTSGQVYPAAAFVHEATAADAETVELNLEPSEGVSYFDRKILGPATQTVPLWVDELLNR-------
>tr|A0A0F3IXS9|A0A0F3IXS9_9PROT NAD-dependent deacetylase OS=Elstera litoralis GN=VZ95_05165 PE=3 SV=1
------------------------------------IRRGDPIVILTGAGISRESGLHTFRDAGGVWSQVKLEDVATPEAYARDPQQVQDFYNARRAQLD
DPAVQPNAAHRALAELEAEW-GPVLIVTQNIDDLHERGG-KSILHMHGELRRVRCTACHDNREVTGDVTLAPKCGNIG---TRRPDIVWFGEIPYGMERI
YGALAECALFLSIGTSGTVYPAAGFVAEASKHGAFCLELNLEPSHGATMFNQALTGPATELVPWLVNMLLGR-------
>tr|A0A0Q5R3B9|A0A0Q5R3B9_9SPHN NAD-dependent deacylase OS=Sphingomonas sp. Leaf357 GN=ASG11_03780 PE=4 SV=1
------------------------------------MKGIRNIVVLTGAGISAESGIATFRG-GGLWEGHRVEDVCTPEALAADAELVHRFYDVRRAALA
T--VVPNAAHDALARLDAEW-GELLIVTQNVDDLHERAAAKRMLHMHGELRSALCAACGSREAWSGDLPP-GACGA-G---ALRPDIVFFGEMPYEMERI
EAALARCDLFVSIGTSGAVYPAAGFVQTARHYGAETLELNLDPSAGSVFFAESRMGAAGVLVPDWVAEVLGW-------
>tr|A0A0Q4KED2|A0A0Q4KED2_9SPHN NAD-dependent deacylase OS=Sphingomonas sp. Leaf33 GN=ASE86_02470 PE=4 SV=1
------------------------------------MTDIRNIVVLTGAGISAESGIATFRG-GGLWEGHRVEDVCTPEALVRDPALVHRFYDLRRAALA
A--VEPNAAHRALARLDAHW-GELLIVTQNVDDLHERAGARRLLHMHGELRSALCARCGARTAWAGDLPP-DACGA-P---ALRPDIVFFGEMPYAMERI
EAALEACDLFVSIGTSGAVYPAAGFVRTARWRGAQTIELNLDPSDGSVFFHESRMGAASVLVPEWVVSVLGD-------
>tr|A0A0Q8QJ04|A0A0Q8QJ04_9SPHN NAD-dependent deacylase OS=Sphingomonas sp. Root710 GN=ASE00_03350 PE=4 SV=1
------------------------------------MSGIHNIVILTGAGVSAESGLGTFRG-GGLWEGHRVEDICTPEALARNRDLVLDFYDQRRAALA
T--VKPNAAHEALARLDCEW-GELLIVTQNVDDLHERAGATRLLHMHGELMSSLCEACGARAGYGGSMLD-GSCGAAD---TLRPDIVFFGEMPYEMDRI
DRALSRADLFLSIGTSGAVYPAAGFVRSARHFGAQTLELNLDPSEGSFFFHESRMGAASELVPEWVGELLAA-------
>tr|A0A0Q8LQI7|A0A0Q8LQI7_9MICO NAD-dependent deacylase OS=Microbacterium sp. Root180 GN=ASD93_03480 PE=4 SV=1
----------------------------------------MRIVVLTGAGISAESGVPTFRD-DGLWEGHDVDDVATPEGFARDPDLVQRFYDARRRAVA
S--VVPNAAHRALARLEGAF-EDLLVVTQNVDDLHERAGTSNLVHMHGELRRALCAGCGARPVWDADLE-RPACGER----MLRPDVVWFGEMPYELDRI
EQALAACDVFASIGTSGAVYPAAGYAALAAAWGAWTVELNLEPSDALVPFDDARSGRAGELVPAWVEELLAT-------
>tr|A0A0P0DJI0|A0A0P0DJI0_9MICO NAD-dependent deacetylase OS=Microbacterium sp. No. 7 GN=AOA12_07400 PE=4 SV=1
----------------------------------------MRVVVLTGAGISAESGVPTFRD-NGLWEGHRVEDVATPEAFERDPVLVQRFYDARRRALA
S--VDPNPAHRALARLEAEL-DDLLVVTQNVDDLHGRAGTTRLVHMHGELRRALCTACAARPAWHDDLI-GPACGER----ALRPDVVWFGEMPYETDRI
ERAVATCDLFVSVGTSGAVYPAAGYAALAAAVGARTLELNLVPTMGIVAFDEVRAGPASVVVPRWVDELRRS-------
>tr|A0A0F2GLQ2|A0A0F2GLQ2_9ACTN NAD-dependent deacetylase OS=Nocardioides luteus GN=UG56_03835 PE=3 SV=1
--------------------------------------MLVKVVVLTGAGISAESGLATFRD-DGLWQGHHVDDVATPEAFHRDPATVHRFYDDRRRELR
T--VTPNPAHIALARLEQVL-DELLVVTQNVDDLHERAGSRRVVHMHGELLSALCDSCQGRFAWDDDLG-GPGCGND----TLRPDVVWFGEMPYDLDLI
EHALVRADLFVAIGTSGAVYPAAGFVRMAAGSGAKTLELNLDPSETSHLFDDARHGPAGKLVPEWVADVQAL-------
>tr|A0A0Q9JML6|A0A0Q9JML6_9MICO NAD-dependent deacylase OS=Agromyces sp. Soil535 GN=ASG80_20570 PE=4 SV=1
-------------------------------------MGGMRIVVLTGAGISAESGVPTFRD-GGLWEGHRVEDVATPEAFERDPDTVQRFYDQRRHAVA
R--AEPNPAHDALARLEREL-DDLLVVTQNIDGLHEQAGSRRVLHMHGELLQALCARCGARSPVMADLL-RPTCGER----MLRPDVVWFGELPYHLDEI
DEALLACDEFAAIGTSGAVYPAAGFVMTAADWGAHTIELNLASSEIAPLFDEVRHGPASIVVPAWVDEVLAA-------
>tr|A0A0M2H6I4|A0A0M2H6I4_9MICO NAD-dependent protein deacylase OS=Microbacterium trichothecenolyticum GN=cobB_1 PE=3 SV=1
---------------------------------------MNRIVVLTGAGISAESGVPTFRG-DGLWEGHSIEDVATPEGFERDPDRVQAFYDARRRAVA
S--VVPNAAHRALARLEGAI-DDLLVVTQNVDDLHERAGTRNLVHMHGELRRALCLACGSRPQWDADLI-GPECGER----MLRPDVVWFGEMPYELDRI
EQAVVACDVFVSIGTSGEVYPAAGYVALAAAFGARTVELNLEPSDPAVAFDETRAGLASELVPAWADEVIAA-------
>tr|A0A0D5LL89|A0A0D5LL89_9RHIZ NAD-dependent deacetylase OS=Martelella endophytica GN=TM49_02050 PE=3 SV=1
------------------------------------ISAHPSIVVLTGAGISAESGLATFRDQGGLWEGHSIEDVATPEGFARNPDLVNDFYNQRRREAK
L--ARPNSAHNALAALENAWDGDFLLVTQNVDELHEKAGSKRVLHMHGRLNSALCYECGSHQHWEDDLDQGQSCTRA----SLRPDIVWFGEMPYDMDAI
GTALGGADLFISIGTSGTVYPAAGFVAEAAHHGARTVEINLESTH-NPLFSDCRQGSASAMVPAFVRELLEA-------
>tr|A0A0Q8AS51|A0A0Q8AS51_9MICO NAD-dependent deacylase OS=Microbacterium sp. Root166 GN=ASD56_13525 PE=4 SV=1
----------------------------------------MRIVVLTGAGISAESGVPTFRD-DGLWEGHLVEDVATPEGFERDPDLVHAFYDARRRAAA
S--VQPNAAHRALARLEGAV-EDLLVVTQNVDDLHERAGTGNLVHMHGELRRALCTSCGARPVWEDDLA-RPACGER----MLRPDVVWFGEMPYELDRI
EQAVAACEVFVSIGTSGAVYPAAGYVALASALGAHTVELNLEPSDAVVPFDDARSGRASELVPAWVDEILEA-------
>tr|A0A0M2GYU1|A0A0M2GYU1_9MICO NAD-dependent protein deacylase OS=Microbacterium ketosireducens GN=cobB_1 PE=3 SV=1
------------------------------------QTGRMRIVVLTGAGISAESGVATFRG-GGLWEGHRVEDVATPEGFERDPAMVQRFYDARRRAVA
S--VHPNAAHRALARLEDAL-DELLIVTQNVDDLHERAGSIRLVHMHGELRRALCTACDARPAWSRDLV-LPVCGER----MLRPDVVWFGEMPYELDRI
EQAVVACDVFVSIGTSGAVYPAAGYAALASAFGARLVELNLEPSDAVVPFDDARTGPATTLVPTWVDEVLAG-------
>tr|R6INR6|R6INR6_9PROT NAD-dependent protein deacetylase of SIR2 family OS=Azospirillum sp. CAG:260 GN=BN570_01690 PE=3 SV=1
------------------------------------SRLYKNIVILTGAGISAESGLATFRSSNGLWNNHRVEDVATVEGFQRNPALVHDFYNELKIEI-
-QKAKPNPAHLAITKLQKEY-GTVSVITQNVDTLHEKAGNTNICHIHGQINQAVCLNCGHILETFGDVDTEPQCGISG---MMKPNIVFFGENLLGMDKV
EQLLQNCDLFISVGTSGVVFPAAAFVQTAKYHGADTWEFTLEPTANNYYFDHHIYGPAGQTLPPFVDNLIRE-------
>tr|R5QMN0|R5QMN0_9PROT NAD-dependent deacetylase OS=Proteobacteria bacterium CAG:495 GN=BN682_01570 PE=3 SV=1
------------------------------------MQKYQNIVILTGAGISAESGLATFRAANGLWNNHRVEDVATVEAFARNPEYVHEFYNELKQEL-
-IRAVPNPAHLALAKLQQNY-APVTIVTQNVDTLHEKAQSTGVLHIHGQINQAVCLNCGHVLETWGDVNTEHQCGVPA---MMKPNIVFFGENLLCMDKV
DRLLEQCDLFVSIGTSGVVFPAASFVQIAKLNGAETYEFNLETTSNNRYFDHHIYGKAGETVPQFVDTLLAE-------
>tr|R6IYH0|R6IYH0_9PROT Silent information regulator protein Sir2 OS=Azospirillum sp. CAG:239 GN=BN554_00936 PE=4 SV=1
------------------------------------NKQYKNIVILTGAGISAESGLATFRSSNGLWNNHRVEDVASVESFRRNPALVHDFYNNLKLEI-
-QKAKPNPAHLAITRLQNEY-AEISVVTQNVDTLHEKAGNKNIYHIHGQINQAVCLNCGHILETFGDVDTEPQCGVVG---MMKPNIVFFGENLLCMDKV
EILLRSCDLFVSIGTSGVVFPAAAFVQTAKYYGADTIEFTLEPTSNNFYFDRHVYGPAGQTLPPYVDGLVKS-------
>tr|R5Y9U0|R5Y9U0_9PROT NAD-dependent protein deacetylase OS=Acetobacter sp. CAG:267 GN=BN575_00583 PE=4 SV=1
------------------------------------AKTYKRILFLTGAGISAESGLATFRSENGLWNNHRVEDVATIEAYYRNQDYVHDFYNNMKPEL-
-WNAKPNAGHLAITRLQQEY-GEVHIITQNIDTLHEKAKSKNVIHIHGQINQAVCMNCGHVLETWGDVTSEENCHIMG---MMKPNIVFFGENLLYMDKV
ERLLSTSDLFVSVGTSGVVYPAAGFVQTAKYYGADTLEFNLEPTSNNFYFDRHIMGKAGDTLPQFVSELLEM-------
>tr|T0HL83|T0HL83_9SPHN Uncharacterized protein OS=Sphingobium lactosutens DS20 GN=RLDS_04395 PE=3 SV=1
------------------------------------THNIQNIVILTGAGISAESGISTFRTKSGVPILHRVEDVCTPEALARDAVLVHRFYDERRARLA
Q--VSPNAAHQALARLDARW-GDLLIVTQNVDDLHERAGAKRLLHMHGELKSALCAACGEAAPWSDALPP-AKCNE-P---RLRPDIVFFGEMPYQMDRI
YDALENADLFVSIGTSGAVYPAAGFVQTARAAGARAIELNLEPSAGSALFDETRLGPATRLVPDLVDALLA--------
>tr|Q1N722|Q1N722_SPHSS Silent information regulator protein Sir2 OS=Sphingomonas sp. (strain SKA58) GN=SKA58_10949 PE=3 SV=1
------------------------------------MNRSDSIVILTGAGISAESGLATFRGP-----GHRVEDVCTPEALARDPATVHRFYDERRAKLA
Q--VAPNAAHQALARLDREW-GGLLIVTQNVDDLHERAGATRLLHMHGELKSALCAACGAAAPWTDALPP-AKCNE-P---RLRPDIVFFGEMPYQMDRI
FAALERADLFVSIGTSGAVYPAAGFVQTARDAGARTIELNLEPSAGSALFDETRLGPATRLVTELVDMLLG--------
>tr|A0A0J9CZ75|A0A0J9CZ75_SPHYA NAD-dependent deacetylase OS=Sphingobium yanoikuyae GN=BV87_06240 PE=3 SV=1
------------------------------------RQDIQNIVILTGAGISAESGIATFRTKNGVPILHRVEDVCTPQALARNPALVHRFYDERRAKLA
E--VAPNPAHEALAALDRAW-GDLLIVTQNVDDLHERAGATRLLHMHGELKSALCAACGKAVAWADPLPP-AGCGA-P---SLRPDIVFFGEMPYDMERI
EEALAQADLFVSIGTSGAVYPVAGFVQMARHYGARTLELNLDPSAGSSYFEESRLGPASELVPELVSDLLG--------
>tr|A0A0F7BMS0|A0A0F7BMS0_MYXFU NAD-dependent deacetylase OS=Myxococcus fulvus 124B02 GN=MFUL124B02_24980 PE=4 SV=1
------------------------------------LDSNTWLLVLTGAGVSAESGVPTFRGM-GLWEDQPVTEVASPQGFAKDPLRVWRFYSQRRAGA-
-ADVSPNPGHDALVAWERHL-DRFLLATQNVDGLHRRAG--RVVEMHGNLFTTRCSNCTRAPFPDT----SPGCKECGA--LLRPHIVWFGEHLD---RI
ESFAGGRLVFLAAGTSGAVYPAAGMVDNVRA-GGETWLVNLDA-ENASSFEHFVQGKSGEVLPKLGRLA----------
>tr|H8N1Q8|H8N1Q8_CORCM NAD-dependent deacetylase OS=Corallococcus coralloides (strain ATCC 25202 / DSM 2259 / NBRC 100086 / M2) GN=cobB1 PE=3 SV=1
------------------------------------LDSKTRLLVLTGAGVSAESGVPTFRGM-GLWENHPVEAVASPQGFEANPALVWRFYSQRRTGA-
-ADVKPNPGHDALVRWEQHL-DRFLLATQNVDGLHTKAG--RVVDMHGNLFRTKCA-CQRAPFADT----SPKCDNCGG--RLRPDIVWFGEMLN---RI
GEFIGTRLVFLAAGTSGAVWPAAGIVDEVRS-RGDTWLVNYES-ANTERFHHFVQGLSGEVLPTLAKLV----------
>tr|Q1D737|Q1D737_MYXXD NAD-dependent deacetylase OS=Myxococcus xanthus (strain DK 1622) GN=MXAN_3337 PE=3 SV=1
------------------------------------LDSNTWLLVLTGAGVSAESGVPTFRGM-GLWEDQPVEAVASPEGFRKDPALVWRFYSERRKAA-
-AAVHPNPGHEALVAWERHL-DRFLLATQNVDGLHTRAG--RVVEMHGNLFKTRCS-CGRPPFEDA----APECDACGK--LLRPHIVWFGEYLA---RI
EDFSGGRFVFLAAGTSGAVYPAAGIVDQVRK-GGKTWLVNLDP-ENSNRFEHRIVDKSGEVLPTLAKLA----------
>tr|A0A0H4WYK5|A0A0H4WYK5_9DELT NAD-dependent protein deacetylase of SIR2 family OS=Myxococcus sp. (contaminant ex DSM 436) GN=A176_003610 PE=3 SV=1
------------------------------------LDSRTWLLVLTGAGVSAESGVPTFRGM-GLWEDQPVEAVASPQGFQKDPALVWRFYSERRKAA-
-ATVHPNPGHEALVAWERHL-DRFLLATQNIDGLHTRAG--RVVEMHGNLFKTRCT-CKRPVFEDA----NPECDACGA--QLRPHIVWFGEYLA---RI
EDFAGGRFIFLAAGTSGAVYPAAGIVDHVRE-GGETWLINLDP-ENSGRFEHSVQGKSGQVLPTLAKLV----------
>tr|L7UAD5|L7UAD5_MYXSD NAD-dependent deacetylase OS=Myxococcus stipitatus (strain DSM 14675 / JCM 12634 / Mx s8) GN=MYSTI_04599 PE=4 SV=1
------------------------------------LDSKTWLLVLTGAGVSAESGVPTFRGL-GLWEGQPVESVASPEGFAKDPLRVWRFYSQRRAGA-
-AEVSPNPGHTALVEWERHL-DRFLLATQNVDGLHRRAG--RIVEMHGNLFTTRCSNCKRAPFPDT----DPGCKDCGS--LLRPHIVWFGEYLV---TI
QGFAGGRLVFLAAGTSGVVYPASGMVDQARA-GGETWLVNLET-ESALRFKHFIQGKSGEVLPKLGRLV----------
>tr|A0A0Q7W3U7|A0A0Q7W3U7_9CAUL NAD-dependent deacylase OS=Caulobacter sp. Root1472 GN=ASD47_19215 PE=4 SV=1
--------------------------------------MGLNVFVLTGAGISAESGLGTFRDASGIWTQYDLSEVATPEGFARDPAKVRAFYNARRANL-
-AGAAPNAAHLALARLQKGLAGRLFLCTQNVDDLHEQGGCSDVVHMHGQLGITRCHGCGATWPDSEPLSGEARCGETG---TARPHVVWFGETPLFLHGI
EDALEDSDLFVAIGTSGAVYPAAGLVAWARRLGIRTCELNLEPSDNARVFDERRYGPATEVVPTWVDEVLGG-------
>tr|A0A0Q6UL89|A0A0Q6UL89_9CAUL NAD-dependent deacylase OS=Caulobacter sp. Root343 GN=ASC70_21640 PE=4 SV=1
----------------------------------------MKIFVLTGAGVSAESGLGTFRDKDGVWTKYDLSEVATPEGFARDPAKVRDFYNARRANLA
G--AAPNAAHLALARLETELAGALYLCTQNVDDLHEKAGSRRVIHMHGELAVTRCHHCEATWPDTAPLTAEEACGRAG---GARPHVVWFGETPLFMDEI
EDALSEADLFVSIGTSGSVYPAAGFVTEARAMGIATCEINLEPSANAYVFDQKLYGPASEVVPAWVEQVLAS-------
>tr|A0A0Q8G0V6|A0A0Q8G0V6_9CAUL NAD-dependent deacylase OS=Caulobacter sp. Root655 GN=ASD79_00445 PE=4 SV=1
--------------------------------------MGLNIFVLTGAGISSESGLGTFRDASGIWTQYDLSEVATPEGFARDPAKVRAFYNARRANL-
-AKAGPNPAHVALARLRRDLAGRLFLCTQNVDDLHEQGGGADVVHMHGELTVTRCHGCGATWPDREALSGEAACGAVG---TARPHVVWFGETPLRMDEI
EEALEEADLFVAIGTSGSVYPAAGFVSRARRLGIRTCEINLAPSDNARAFDERRYGPATEVVPAWVDEVLRD-------
>tr|A0A0N7JH01|A0A0N7JH01_9CAUL NAD-dependent deacetylase OS=Caulobacter henricii GN=AQ619_00810 PE=4 SV=1
------------------------------------MVQPLNIFILTGAGISAESGLKTFRDSDGLWTQNDLAQLATPEGFARDPARVRDFYSARRKIL-
-EIAAPNLAHIALARLEREMAGWVFLCTQNVDDLHEKAGSRRVIHMHGELTRTRCTQCSGDWSDRKPLTADPECGTIG---ATRPHVVWFGELPMHMAQI
NQALEEADLFVAIGTSGSVYPAAGFVAEARALGIPTCEINVARSDNAHAFDRRIYGPATEKVSQWVGEVLGD-------
>sp|Q9A2S6|NPD_CAUCR NAD-dependent protein deacylase OS=Caulobacter crescentus (strain ATCC 19089 / CB15) GN=cobB PE=3 SV=1
------------------------------------MRGIMKVFVLTGAGVSAESGLGTFRDKDGVWTKYDLNEVATPQGFARNPALVRDFYNARRANLA
G--ARPNAAHDALAQLEAGLRGELFLCTQNVDDLHEKAGCRRVIHMHGELAVTRCHHCEATWPDTGPLKPDAACARDG---GARPHVVWFGEIPLFMDQI
EDALSAADLFVSIGTSGSVYPAAGFVAEARAMGIATCEINLEPSANAYVFDEKVYGPATEVVPAWVERLLAR-------
>tr|A0A0Q7TD85|A0A0Q7TD85_9CAUL NAD-dependent deacylase OS=Caulobacter sp. Root1455 GN=ASD21_11305 PE=4 SV=1
------------------------------------LPMGLNVFALTGAGISAESGLGTFRDASGIWTRYDLSEVATPEGFARDPAKVRAFYNARRANL-
-AGAAPNAAHLALARLQAGLAGRLFLCTQNVDDLHEQGGCVDVVHMHGQLRVTRCHGCEATWPDPGPLSADPACGVVG---TARPHVVWFGEVPLFMDAI
DDALEDSDLFVSIGTSGAVYPAAGLVARARRLGIRACELNLEPSDNARAFDERRYGPATEVVPAWVDEVLGG-------
>tr|A0A0F9W7B2|A0A0F9W7B2_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_0002600 PE=3 SV=1
------------------------------------MVAARRIVVLTGAGISAESGIRTFRASDGLWEDHKVEDVATPEGFAANPVAVHQFYNDRRRLLL
NASIRPNPAHTALARLEHSP--DFLLITQNIDNLHERAG-RALVHMHGELLKMRCEQSGLSFDIREDLMLDRCCREPG---NLRPDVVWFGEIPLSMAKI
TKALTQCDLFIAIGTSGNVYPAAGFFELAREHGAHTVELNLEST--NADFDEHICGPASTVVPDYVERLLSS-------
>tr|T0T897|T0T897_9DELT Transcriptional regulator, Sir2 family OS=Bacteriovorax sp. DB6_IX GN=M901_2744 PE=3 SV=1
------------------------------------NFNPQHIVILTGAGISAESGIRTFRDANGLWEDHDIMEVASPQGFDRDPELVHRFYNLRRQQLL
SDEVHPNQAHLSLAKLEEDFK-KLSIITQNVDNLHEQAG-KNVIHMHGELLRMKCVETGKSLLNKRDIHVEPCCLKTG---NLRPDIVWFGEYPMHMAKI
EEELSQCDLFISIGTSGVVYPAAMFVQLAKSNGAYCIEVNLEQTQVSDDFDMHMQGPATETVENLVKLILS--------
>tr|C6XKE4|C6XKE4_HIRBI Silent information regulator protein Sir2 OS=Hirschia baltica (strain ATCC 49814 / DSM 5838 / IFAM 1418) GN=Hbal_0040 PE=4 SV=1
------------------------------------YVQFKHVVLLTGAGVSVESGIPVYRNE-EIWTRKEMENFFRPDTFRKNPELVHDFYNKRRMDL-
-KKIQPNKTHCHIAYLQDQL-TKLTIITKNVDDLHEKAG--DVIHILGDLNSAFCT-CNIRIKCMG----LTICSNCKN--KMRPDIVWAGEKPY---KI
QAALDECDLFVSIGTSGSVYPTADFVNLAKK-GAVTVELNQKP-ANATSFDHTNYGPASTIVPFWVDTFIHG-------
>tr|A8U4G8|A8U4G8_9PROT Silent information regulator protein Sir2 OS=alpha proteobacterium BAL199 GN=BAL199_14145 PE=3 SV=1
------------------------------------LKPTDAIVILTGAGISKESGLETFRDADGTWARHRIEDVATPEAFARDPALVHDFYNARRQSML
NPNVQPNAAHTALARLEREW-GPVLLVTQNIDDLHERAG-TALIHMHGEMLKARCEDCTVIEPWQSDLALDPSCRRAG---GMRPHVVWFGEIPLEMDRI
VAALAECALFISIGTSGNVYPAANFVREARWAGAHTVELNLEPSMGATDFDEARHGPATVVVPAFVEELLTS-------
>tr|A3UI70|A3UI70_9RHOB NAD-dependent deacetylase OS=Oceanicaulis sp. HTCC2633 GN=OA2633_09764 PE=3 SV=1
------------------------------------MARFENIVILTGAGVSAESGLGTFREEGGLWAKFDPMKLATPEAFEADPDTVLGFYNARRANLS
D--ARPNAAHFALAELEQNWLANYLLVTQNIDDLHEQAGSANLLHMHGELLKTRCTRCGHLFFDREDMTRTPDCGKAG---GLRPHVVWFGEMPLGLDQI
YQSLERCELFVAIGTSGTVYPAAGFVSEARRGGAHTVELTLEPGEISDLFEEQHYGPATEIVPDWVRRLG---------
>tr|K2J2C0|K2J2C0_9PROT NAD-dependent deacetylase OS=Oceanibaculum indicum P24 GN=P24_16722 PE=3 SV=1
--------------------------------------MAESIVILTGAGISKESGLDTFRDADGIWSRVRIEDVATPQAFRDNPLRVHDFYNARRQQLL
ESNIQPNPAHLALARLQRDW-GEVLLVTQNIDDLHERGG-ASVLHMHGELLKARCTHCHVVAEWRAPLSVGPSCGHAA---GLRPHVVWFGEMPLEMERI
YTALDACGLFVSIGTSGNVYPAAGFVDEVSRRHAHTVELNLEPSSGTDLFDEAIHGPASEIAPAFVERVLTS-------
>tr|Q2W904|Q2W904_MAGSA NAD-dependent protein deacetylase OS=Magnetospirillum magneticum (strain AMB-1 / ATCC 700264) GN=amb0867 PE=3 SV=1
------------------------------------LPGNGTIVVLTGAGISKESGLDTFRDKDGIWAKVRMEDVATPDGFRRDPAKVHAFYNARRRNLA
EGGVAPNAAHAALARLEREW-GEVLLVTQNIDDLHERAG-ENLIHMHGELLKIRCVKCARPFAWTRDLGIEPDCYRVG---SLRPHVVWFGEVPLHMERI
FEALAQCALFLSIGTSGHVYPAAGFVQTVRGLRAQAVELNLEPSEGASLFHESRLGPASRLVPAFVEDLLSR-------
>tr|Q2RN56|Q2RN56_RHORT Silent information regulator protein Sir2 OS=Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIB 8
------------------------------------L-LPCPIVILTGAGVSKESGLDTFRDRDGVWARVRLEDVATPEGFARDPALVQAFYNDRRRGLL
DPSCLPNPAHEALARLEREW-DEVLIVTQNIDDLHERAG-RQLIHMHGELTKARCLDCGAVLDWRADLGESPACATVG---TLRPHIVWFGEIPLEMERI
QDALSTCGLFLSIGTSGNVYPAAGFVRQARFEAAHTVELNLEPSLGATLFEESLYGPASEVVPAYVERLLGA-------
>tr|A0A0A0CWL3|A0A0A0CWL3_9PROT NAD-dependent deacetylase OS=Inquilinus limosus MP06 GN=P409_34515 PE=3 SV=1
------------------------------------IEPGDPIVILTGAGISKESGLDTFRDAGGVWTRVRLEDVATPEAFERDPDRMHGFYNARRRTLA
DPAVQPNAAHAALARLEREW-GPVLLVTQNVDDLHERGGSRRPIHMHGQLNRVRCLACGAGRGWAGDLSVDPGCGQTG---GMRPDVVWFGEMPLAMDEI
ETALAGCRLFVSIGTSGTVYPAAAFVHQALDAGALTMELNLEPGEGSGLFHIRRHGPATRLVPELVAALLAG-------
>tr|H8FV57|H8FV57_PHAMO NAD-dependent deacetylase OS=Phaeospirillum molischianum DSM 120 GN=npdA PE=3 SV=1
------------------------------------VSQPGSIVVLTGAGISKESGLDTFRDRDGLWARVRIEDVATPEGYRRDPQRVQAFYNARRRELS
EGGVEPNPAHLALARLEREW-GEVLVVTQNIDDLHERAG-SRLIHMHGELLKVRCVRCARPLPWAADIEATPECGRAD---VLRPHVVWFGEVPLEMDRI
LSALERCFLFVSIGTSGHVYPAAGFVAAVRDARARAVELNLEPSHGASLFHEVRTGPASVLVPAFVEEVLTS-------
>tr|A0A061IXF5|A0A061IXF5_TRYRA NAD-dependent deacetylase OS=Trypanosoma rangeli SC58 GN=TRSC58_04946 PE=3 SV=1
------------------------------------KPRCQWITILTGAGVSAESGLSTFRDKDGLWENHSIEEVACPYAFMRNPQLVQRFYNERRRALL
SPAVRPNPAHMAIAMLQREY-GRVVVVTQNVDNLHERAGSTSVLHMHGELLKVSCIATGEVFDWTQDVVHTKCCNAVE---TLRPHIVWFGETPFHLDEI
NTVMKNTDLFVAIGTSGNVYPAAGLVMHSKENGAKTLELNLAPGENFSDFDESIYGKASEIVPAWVDRLLQT-------
>tr|Q4CNV0|Q4CNV0_TRYCC NAD-dependent deacetylase, putative OS=Trypanosoma cruzi (strain CL Brener) GN=Tc00.1047053447255.20 PE=3 SV=1
------------------------------------RPRRQVVTILTGAGISAESGLSTFRDKNGLWENHRVEEVACQYAFLRNPLLVQRFYNERRRALF
SDCVAPNPAHLALAKLQREYR-RVVLVTQNVDNLHESAG-VSVLHMHGELLKVRCTVTEEVFDWTQDVHGTKCCNAVD---TLRPHIVWFGEMPLHMDEI
NAAVEETDLFVAVGTSGNVYPAAGFVTRAREKGARTLELNLDSGTNVSEFDESIYGKASVIVPAWVDKLLQD-------
>tr|F9WEX1|F9WEX1_TRYCI WGS project CAEQ00000000 data, annotated contig 322 OS=Trypanosoma congolense (strain IL3000) GN=TCIL3000_0_08380 PE=3 SV=1
------------------------------------RRRGRTLAILTGAGISAESGIPTFRDKNGLWENHRVEDVCSPRAFLHHPLVVQRFYNQRRRALL
SPEVKPNAAHMALARLERDYT-EVVVITQNIDDLHERAG-KNVVHMHGELLKVRCTTTGNVFEWKDDIHGQACCGALG---TLRPHIVWFEEVPLYMDVI
SDVVEKADIFAAIGTSGNVYPAASFASLAAANGAETYELNLEPGENSEDFQHNIYGPASVVVSKWVEGLLRG-------
>tr|J0ZSF9|J0ZSF9_9RHIZ Uncharacterized protein OS=Bartonella tamiae Th239 GN=ME5_00082 PE=3 SV=1
------------------------------------MHNLNNIVILTGAEISAESGLETFRSEDRTWNKFRIEDVATPQAFQKNPTRVYDFYNKRRQDV-
-QKAKPNAAHHALYKLEQNW-RNFLLITQNVDDLHERAGSKHLVHMHGTIKIALCLFCGQRHHWCEDMDLTPSCTKTK---MLRPDIVWFGEIPYHMDII
ENALYQCDLFVSIGTSVTVYPAANFVSMAKANGAKSIDMNLMSDTNNSLFNQSIIGSASQSVPKFVCNLLQK-------
>tr|A0A074JJ70|A0A074JJ70_9PROT NAD-dependent deacetylase OS=Thalassospira permensis NBRC 106175 GN=SMB34_02800 PE=3 SV=1
------------------------------------RDEAATIVILTGAGISKESGLHTFRDPDGIWAKYDISEVATPEAFINNPDLVHHFYNDRRAGLL
DPAIQPNKAHLALARLETRW-SDVLLVTQNIDDLHYRAGSKNLIHMHGELLKISCNHCGLLTVWSAPLGRDTSCTKTG---GLRPHVVWFGEMPFEMERI
YAALSKCGLFISIGTSGNVYPAAGFVQIASEAGAETVEINLEPGSGASLFDHSSYGLATKLVPALIDSLLMD-------
>tr|A0A0D8CDM8|A0A0D8CDM8_9PROT NAD-dependent deacetylase OS=Thalassospira sp. HJ GN=UF64_17405 PE=3 SV=1
------------------------------------RDEKSPIVILTGAGISKESGLHTFRDPDGIWAKYDISEVATPEAFIANPDLVHHFYNDRRASLH
DPDVQPNAAHLALARLEAEW-GDVLLVTQNIDDLHGRAG-KNLIHMHGELLKIRCNHCDLLTEWPGDLAKEPSCGKAG---GLRPHVVWFGEMPLEMERI
YAALGECGLFISIGTSGNVYPAAGFVQIAHEEGAETVELNLEPSSGATQFDHSRYGPATELVPAFVSALLGD-------
>tr|A0A037UVP6|A0A037UVP6_9RHIZ NAD-dependent deacetylase OS=Rhodomicrobium udaipurense JA643 GN=T281_15660 PE=3 SV=1
------------------------------------MSRYNSIVILTGAGLSAESGLHTFRDKDGIWAKYDYREVATPEGYKRNPKLVLQFYNERRKQNA
D--VQPNAAHLALARLEAEYPGGVLIVTQNIDPLHEMAGSKKLVHMHGEIMKALCAACATRHALHDDITLKPSCGRTG---VLRPDVVWFGELPYEMERI
YRAILGCDLFISIGTSGTVYPAAGFVEEALRVGAHTVELNLEPSHGISRFIDAIHGPATEVVPAYVERLLKR-------
>tr|D9Y4J2|D9Y4J2_9BURK Putative NAD-dependent deacetylase OS=Burkholderiales bacterium 1_1_47 GN=HMPREF0189_00966 PE=4 SV=1
------------------------------------KGDRPLVFILSGAGLSAESGIPTFRDA-GLWRKYDPKELASIRALERHTQDVFDFYNERIKNA-
-EPCRPNAAHIAIANFQKEM-CDVIHVTQNVDNLNELAG--RVFHLHGDFQTSLCR-CKKTFPRLG----EPVCEATNF--AMRPNVVLFGEIPY---WI
TSYLKKACVFISIGTSGTVYPAANFVKETKA-SI---RINLDL-PLIHPYTNRIYGKCTETLPPLLDQLKQE-------
>tr|D5WUC7|D5WUC7_KYRT2 Silent information regulator protein Sir2 OS=Kyrpidia tusciae (strain DSM 2912 / NBRC 15312 / T2) GN=Btus_2730 PE=4 SV=1
------------------------------------LRKARRAVALTGAGMSTESGIPDFRS--GLWAQVDPREVATVEALETNYPRVREFYRKRIDEI-
-KKHRPHLGHEILARWEKA--RLQAVATQNIDGFHQMAG--AVHELHGSLRRFYCL-CGRPATEAE-F---EPCPHCRG--RLRPGVVMFGELLD---AA
ETAMRAADLVLVIGTSLEVYPVNQLPAL----QGKRVLINLEP-DQQALFDEVLIGRAGEVLAAIDREMGNQ-------
>tr|D5WUB5|D5WUB5_KYRT2 Silent information regulator protein Sir2 OS=Kyrpidia tusciae (strain DSM 2912 / NBRC 15312 / T2) GN=Btus_2718 PE=4 SV=1
------------------------------------IRDSRQTVVLTGSGMSTESGIPDFRSQGGLWARVDPRRVATVEALEANYPEVRDFCRKRIEEI-
-KRNRPHRGHEILAGWEH---RVRAVATQNIGGFHQIAG-RTVHELHGSLRRFHCRECGRPAAE------GRPCRHCRG--RLRPDVVMFGELLDVWDAV
VAAMHAADLVLVIGTSLEVYPVNQLPALSQ---GRRVLINLED---QALFDEVLLGKAGEVLSAIDREM----------
>tr|W0NUG1|W0NUG1_9ZZZZ NAD-dependent protein deacetylase OS=uncultured organism GN=cobB PE=3 SV=1
------------------------------------IVEAQPCVVLTGAGVSTESGIPDFRS--GIWATYDPMEYATIDAFHRNPGKVWEFYSKRLGVL-
-AEAQPNAAHMALAELEQF--LVGAIVTQNVDRLHQEAG--RVLEVHGSIRSASCS-CGHREDFDR-V---PTCADCGG--VLKPDVVMFGELLG---QA
SRLAQSAGLMLVVGSSLEVYPVAGLPEDTLQ-GGRLAIVNRGS-PYDGRADLKIDASAAETLAAVTERLRPG-------
>tr|F5L4Y1|F5L4Y1_9BACI NAD-dependent deacetylase OS=Caldalkalibacillus thermarum TA2.A1 GN=CathTA2_0844 PE=4 SV=1
------------------------------------LLEAQHTVILTGAGMSTESGLPDFRSNQGLWYGRDPQEIASVYAIKHNREDFVDFYRWRIKEV-
-DKYKPHIGHHLLTRWQR---LVQRIITQNVDGFHHQAE-HDVIELHGSLRELYCMDCGHRTEA------EEVCPQCGG--FLRPDIVLFGEMLQAIETA
FAEARQAELFIVLGSSLQVSPANMLPMEAKE-GAKLAIVNLHD-LLDPQADLLIEGKVGEVLQKTDEWLNRK-------
>tr|B8FEP4|B8FEP4_DESAA Silent information regulator protein Sir2 OS=Desulfatibacillum alkenivorans (strain AK-01) GN=Dalk_1874 PE=4 SV=1
------------------------------------IAEGGRNIAFTGAGISTESGIPDFRSQGGIWDQYRPVYFDEFMSSRDARVRYWDQKIAMWDGL-
-EKARPNAGHQALAKLYD---LLEAIITQNIDGLHQESG-DKVIELHGNTRRVRCMTCGETSTV------GAPECHCGG--YLKPDTISFGQAMKEVEAA
ARLSSSCDFFLVVGSTLVVHPAAMMPEYARR-GAYLAIVNLSD-PYDNACQALVREKAGPVLQAIADMAEEY-------
>tr|A0A094K8B9|A0A094K8B9_9BACL Uncharacterized protein OS=Thermoactinomyces sp. Gus2-1 GN=JS81_04235 PE=4 SV=1
------------------------------------VQNANHLVVLTGAGMSTESGLPDFRSQGGLWSGRDPNEIATPGAIG--TKDFFEFYQMRVEEL-
-LKHHPNIGHYVLAELEK---MVKAILTQNIDGFHQRAG-QKVIEIHGHMRHLVCSGCGKEYPA------GCTDEQCQA--PLRPPIVLFGEPLASWNEA
VLEVEKADLILVMGTSLQVYPFAGLVEIAHE-GSDVIIINQSA-PLDSLADQLIRDSIGLVLSEAGKALLGE-------
>tr|A0A084UCS6|A0A084UCS6_9RHIZ NAD-dependent protein deacylase OS=Nitratireductor basaltis GN=cobB PE=3 SV=1
-------------------------------------MRPERIVILTGAGISAESGVDTFRDKDGIWSKYDYRDVATPEGFDADPELVHDFYNARRAGLA
-K-VKPNAAHKALARLEEAY-KRLVLVTQNIDDLHERGG-RNVVHMHGELKRALCSHCGQRHDWEGDLSTAPSCHLKG---SMRPDVVWFGEMPYHMERI
YDALRDCDLFLSIGTSGNVYPAAQFVQEAARA-AHTVELNLEPSQSMREFGELIHGPATRVVPRYVDGLLRR-------
>tr|A0A060D912|A0A060D912_AZOBR NAD-dependent deacetylase OS=Azospirillum brasilense GN=ABAZ39_00640 PE=3 SV=1
------------------------------------LKPTDSIVILTGAGISKESGLDTFRCADGIWAKVDLEDVATPEGFARDPALVHRFYNDRRRGLR
DPAVQPNAAHLALAELEGRW-GDLLLVTQNIDDLHERGG-QTLIHMHGELNAVFCRHCHNKVEWTSDLSVEPSCARKG---GMRPDVVWFGEMPYQMERI
YRALGACDLFVSIGTSGNVYPAAGFVAEARNA-ALTLELNLEPSAGASLFADSVNGPATELVPAFVSELLSL-------
>tr|A0A0F2KZR6|A0A0F2KZR6_9PROT NAD-dependent deacetylase OS=Azospirillum thiophilum GN=AL072_03525 PE=3 SV=1
------------------------------------LRPTDSIVILTGAGISKESGLDTFRCEGGIWSQVDLEDVATPEGFARDPDLVHRFYNDRRRGLA
DPAVQPNDAHRALAELERRW-GELLLVTQNIDDLHERGG-TAPLHMHGELLKAVCLHCRTVVEVQGDLSVHLACGRKG---GMRPDVVWFGEMPYRMDRI
QRALEECDLFVSIGTSGHVYPAAGFVAEARSA-AYTVELNLEPSEGASYFHSSIHGPATRVVPAFVQDLLTL-------
>tr|K9HRG0|K9HRG0_9PROT NAD-dependent protein deacetylase of SIR2 family OS=Caenispirillum salinarum AK4 GN=C882_1716 PE=3 SV=1
------------------------------------TADQPSIVILTGAGISKESGLDTFRCADGIWNKVSLEDVATPEGFARDPDMVHGFYNARRAQLA
DPTLSPNAAHEALARLEREW-GEVLVVTQNIDDLHERGG-KNVLHMHGELKKVRCEGCRAVAVWDGDLGRDPTCGVAG---AMRPHVVWFGEMPLGMERI
YAALEDCALFLSVGTSGNVYPAAGFVHHVLETGGRTVELNLEPSQGATLFAEQHYGPATEVVPAFVDRLLAE-------
>tr|F8J9V0|F8J9V0_HYPSM NAD-dependent protein deacetylase, regulatory protein SIR2 family OS=Hyphomicrobium sp. (strain MC1) GN=cobB PE=3 SV=1
------------------------------------IAQHPKIIILTGAGLSAESGVPTFRDPNGMWAKYDWRDVATPDGFQRDPALVLNFYNARRRAHR
G--IKPNAAHIALARLEAEH-GGVTVVTQNIDALHEAAGSHSLIHMHGELFKALCTFCKHRVPWQGDLLVDPYCGLPG---GMRPDVVWFGEMPYQMGRI
TGLLGEADLFLSIGTSGHVYPAAGFVAEAREHGARTVELNLEPSEGASQFDEAIYGHATEIVPAFVDRILAG-------
>tr|A0A0Q4EF31|A0A0Q4EF31_9SPHN NAD-dependent deacylase OS=Sphingomonas sp. Leaf208 GN=ASE69_14805 PE=4 SV=1
------------------------------------MRDIQNIVILTGAGVSAESGVPTFRSKDLAPKSYRIEDVCTPEALAADPELVHRFYDLRRTALA
T--VEPNAAHHALARLDAAW-GELLIVTQNVDDLHERVGATRMLHMHGELLSALCAVCGAREPWSGALPE-DACGA-A---ALRPDIVFFGEMPYQMERI
EAALAKADLFVSIGTSGAVYPAAGFVQTAAYHGARTLELNLDPSMGSVFFEQTRIGAAGVLVPAWVDEVLGS-------
>tr|A0A0Q4IA99|A0A0Q4IA99_9SPHN NAD-dependent deacylase OS=Sphingomonas sp. Leaf226 GN=ASE77_00980 PE=4 SV=1
------------------------------------MQDLRNIVILTGAGISAESGIATFRG-GGLWAGHRVEDVCTPEALAADPELVHRFYDLRRAALA
T--VEPNAAHRALARLDEAW-GGLLIVTQNVDDLHERAGATRMLHMHGELLSALCAVCGAREPWAGSLPE-GACGS-A---ALRPDIVFFGEMPYQMERI
EAALAQADLFVSIGTSGAVYPAAGFVQTAAYHGAATVELNLDPSMGSVFFEETRIGAAGMLVPAWVDEVLGR-------
>tr|A0A0Q4R735|A0A0Q4R735_9SPHN NAD-dependent deacylase OS=Sphingomonas sp. Leaf242 GN=ASF09_11540 PE=4 SV=1
------------------------------------MAPYESIVILTGAGISAESGIPTFRTQDGVRKKHRVEDVCTPEALAADPELVHRFYDLRRAALA
T--VEPNAAHHALARLDAAW-GELLIVTQNVDDLHERAGATRILHMHGELLSALCAVCGARESWSGALSE-GACGA-A---ALRPDIVFFGEMPYHMERI
EAALAKADLFVSIGTSGAVYPAAGFVQTAAYHGARTLELNLDPSMGSVFFEQTRIGAAGVLVPAWVDEVLGR-------
>tr|A0A0Q6L120|A0A0Q6L120_9SPHN NAD-dependent deacylase OS=Sphingomonas sp. Leaf339 GN=ASG67_16335 PE=4 SV=1
------------------------------------MNKPRNIVVLTGAGVSAESGLPTFRSKYLGPKSYRVEDVCTPEALAGDPVLVHRFYDARRAALA
G--VAPNAAHIALARLDAAW-GELLIVTQNVDDLHERAGATRLVHMHGELRSALCAACGARRPHAGDLPP-PACGA-P---ALRPDIVFFGEMPYQMARI
EAAVADADLFVSIGTSGAVYPAAGFVQMAAHYGAATLELNLERSAGSSSFDETRLGLAGVLVPAWVEEVLAT-------
>tr|A0A0D1K0Z8|A0A0D1K0Z8_9SPHN NAD-dependent deacetylase OS=Sphingomonas taxi GN=SR41_11055 PE=3 SV=1
--------------------------------------MVKSIVILTGAGISAESGVPTFRSKDFVPKSYRVEDVCTPEALAADPALVHRFYDLRRAALA
E--VAPNAAHMALARLDRAW-DELLIVTQNVDDLHERAGATRLLHMHGELRSALCAVCGIREDWDGALPP-PNCGE-P---ALRPDIVFFGEMPYHMDRI
EAALAACDLFVSIGTSGAVYPAAGFVQMAEAYGADTLELNLERSAGSGFFAETRLGPAGELVPAWVDALLAE-------
>tr|A0A099BSU2|A0A099BSU2_9HELI Uncharacterized protein OS=Helicobacter sp. MIT 03-1614 GN=LS66_04365 PE=3 SV=1
------------------------------------RSENAKLVVFSGAGLSAESGLETFRDNGGLWAQYDPMEVCNYENWLDNFELVHRFYNLRREEL-
-GKVQPNAMHKFLASLPMILIIEVIHITQNVDDLLERAG--NVIHLHGELCKIICPQCEHIFDI-------HNCPNCDY-GKLKPFIVFFYERAYIMHDI
FSQLSSKDCVLVIGTSGNVVDISTILAFAES-RGYKILNNLQP-IAESVFDKIFYKPTTQAIAEIEQELEQF-------
>tr|A0A099DPF6|A0A099DPF6_9HELI Uncharacterized protein OS=Helicobacter sp. MIT 09-6949 GN=LS71_04505 PE=4 SV=1
---------------------------------------MPKLVVFSGAGLSAESGLATFRNSNGLWAQYDPMEVCNYENWLDNFALVHRFYNLRRQEL-
-AKVQPNAMHKYLATLDKKL-VEVIHITQNVDDLLERAG--NIMHIHGELTKLICPQCQHVTNI-------APCEQCGY-TKVKPKIIFFFEQAYPMYEI
LSSLSHNDMALVIGTSGNVVDISMLLTYAQR-GGSKILNNLAK-ITESVFDKIFYKPTTEAIADIDKEILAF-------
>tr|V8CA41|V8CA41_9HELI Uncharacterized protein OS=Helicobacter macacae MIT 99-5501 GN=HMPREF2086_00984 PE=4 SV=1
------------------------------------SKKHRKLVVFSGAGLSADSGMATFRDSDGLWASYDPLEVCNFKNWEKNYELVHRFYNLRREEL-
-KSVKPNAMHEFLANLPNLL-IEVIYLTQNVDDLLERAG--NVIHLHGELTKIICPKCHHISDI-------TPCPKCAN-KKQKPKIVFFYESAYVMNAV
FFSLGKDDSVLVVGTSGSVIPIGVILGQ----SGLKILNNLAP-IDEGLFDKVIYSKAIEAIPQIKQEIETF-------
>tr|A0A099BC03|A0A099BC03_9HELI Uncharacterized protein OS=Helicobacter sp. MIT 01-6451 GN=LS65_07320 PE=4 SV=1
---------------------------------------MPKLVVFSGAGLSAESGLETFRDNGGLWGQYDPMEVCNYENWLENFELVHRFYNLRREEL-
-GKVQPNAMHNFLAALPDIL-IEVIHITQNVDDLLERAG--NVIHLHGELTKIICPKCAQITDI-------HHCPKCDY-RYLKPFIVFFYEKAYTMYDI
FESLNFRDCVLVIGTSGNVVDISSILARCEY-KGLKILNNLEK-IAESVFDKILYKPATQAIDELKENLSHF-------
>tr|A0A099TQ49|A0A099TQ49_9HELI Uncharacterized protein OS=Helicobacter sp. MIT 03-1616 GN=LS67_00475 PE=4 SV=1
---------------------------------------MPKLVIFSGAGLSAESGLETFRDNGGLWAQYDPMEVCNYENWLENFALVHRFYNLRREEL-
-GKVQPNAMHKFLATLPHSL-IEVIHITQNVDDLLERAG--NIIHLHGQLSKIICPKCEYIFDI-------HNCPNCGY-EKLKPFIVFFYEKAYTMYEI
FESLNFRDCVLVIGTSGNVVDISSILARCEY-KGLKILNNLEN-IAESVFDTIYYKPATQAIEQIQEALCDF-------
>tr|A0A099TUX5|A0A099TUX5_9HELI Uncharacterized protein OS=Helicobacter muridarum GN=LS73_09470 PE=4 SV=1
---------------------------------------MAKLIIFSGAGLSAESGLSTFRDNNGLWAKHDPMEVCNYKNWLKNFNLVHDFYNLRRKEL-
-KQAKPNDMHKFLAKLSSIF-IEIIHVTQNVDDLLERAG--NVVHLHGELTKIICPQCETILNI-------HDCETCGY-KYLKPFIVFFFEEAYLLHQV
FSNLTNKDCVVVIGTSANVIDINSLLIRR-T-QGFKILNNLEP-IMESLFDMKLYMTATQAINSIQEGLIDF-------
>tr|A0A0C6FHK3|A0A0C6FHK3_9RHIZ Sir2 protein OS=Methylobacterium aquaticum GN=sir2 PE=3 SV=1
------------------------------------SRPVARVFVLTGAGISAESGLGTFRDPGGLWRRFDPMRLATPEAFAREPEEVHAFYNLRRQGV-
-REAAPNAAHAALARLEVGLAGGLFLCTQNVDDLHERAGSRSVVHMHGELMRVRCTACGAAAPWAEDLGLDPACGRRG---GMRPDVVWFGEVPLHLDAI
GDALAAADLFVAIGTSGAVYPAAGFVAQARAAGIPTREINLAPSDTAGLFDEATYGPATRAVPDFVAELLDE-------
>tr|A0A0P7Y146|A0A0P7Y146_9RHIZ NAD-dependent deacetylase OS=Rhizobiales bacterium HL-109 GN=npdA PE=4 SV=1
----------------------------------------MRIFVLTGAGISAESGMGTFRDSGGIWERFDPMKLATPEAFAADPETVQAFYNARRANLR
R--AEPNRAHEALAHLETGLAGSLFLCTQNIDDLHERAGSLHVHHMHGELFKARCTACGAVHDWRDDLGTGAACGTTG---RLRPHIVWFGEIPFGLDAI
GEALAGADLFVAIGTSGSVYPAAGLVREARMMGLRTCELNLEPSDNADVFDERAYGPASEVVPDFVARLLAE-------
>tr|A0A0E9KAL8|A0A0E9KAL8_9RHIZ Silent information regulator protein Sir2 OS=Methylobacterium sp. ME121 GN=ME121_3647 PE=3 SV=1
------------------------------------TDHPRTIFVLTGAGVSAESGLGTFRDRGGIWARFDPMKLATPEAYAADPDTVLDFYDHRRRGV-
-VAAEPNAAHRALARAETRIAGRLFLCTQNVDDLHERAGSRAITHMHGELLKARCCACTAVTPWRADLSRAPACGAAG---RMRPDVVWFGEMPMHLDAI
EAALAEADLFVAVGTSGAVYPAAGYVRQARALGIPTCEVNLEPSDNADAFDDARYGPASAALPRYLAELGL--------
>tr|B8IBW7|B8IBW7_METNO Silent information regulator protein Sir2 OS=Methylobacterium nodulans (strain ORS2060 / LMG 21967) GN=Mnod_6362 PE=3 SV=1
----------------------------------------MNIFVLTGAGISAESGLGTFRDRGGLWSRFDPARLATPEAFAEDPDTVHAFYNLRRRGV-
-CDAAPNAAHRALARLQAALAGRLFLCTQNIDDLHERAGASDVVHMHGEIFRARCLSCGASHPWRANLGVAPACGRAG---GMRPDVVWFGEVPLHLDAI
DAGLAAADLFVAIGTSGVVYPAAGYVAQARRRGIPTHEINLAPSDTAHVFDTAAYGPATETVPAWVEAVLAR-------
>tr|A0A0J6QQ38|A0A0J6QQ38_9RHIZ NAD-dependent deacetylase OS=Methylobacterium platani JCM 14648 GN=SQ03_27375 PE=3 SV=1
----------------------------------------MNVFVLTGAGISAESGLGTFRDPGGLWRRFDPMRLATPEAFAREPEEVHAFYNLRRHGV-
-RQAEPNAAHAALVRLESGLAGRLFLCTQNVDDLHERAGARAVTHMHGELMRARCTACGESRPWAEELGLGPACGRRG---GMRPDVVWFGEMPFHLEAI
AEALDAADLFVAIGTSGAVYPAAGFVARARGAGIPTREVNLAPSDTAGLFDDARYGPATRAVPEAVDEILRE-------
>tr|A0A0J6SPL3|A0A0J6SPL3_9RHIZ NAD-dependent deacetylase OS=Methylobacterium tarhaniae GN=VQ03_19620 PE=3 SV=1
----------------------------------------MNVFVLTGAGISAESGLGTFRDPGGLWHRFDPMRLATPEAFADEPEEVHAFYNLRRQGV-
-RETVPNAAHAALARLEAGLAGRLFLCTQNVDDLHERAGSRAVTHMHGELLRARCTACGESRPWADDLSVDPACGRRG---GMRPDVVWFGEVPLHLDAI
ARALDAADLFVAIGTSGAVFPAAGFVARARGAGIPTHEVNLAPSDTAGLFEAATYGPATRAVPGFVDDLLTT-------
>tr|E0TE48|E0TE48_PARBH NAD-dependent deacetylase OS=Parvularcula bermudensis (strain ATCC BAA-594 / HTCC2503 / KCTC 12087) GN=PB2503_03972 PE=3 SV=1
----------------------------------------MRLVILTGAGISADSGVDTFRDEGGVWSQVRLEDVATPEAFLHTPDRVHAFYNRRRAQL-
-PNVAPNAAHLALAALERRLEHEFVLITQNVDNLHQRAGSDSVFPMHGQLDRALCVHCGGVVALTEDLSTKPQCQRQG---GMRPNIVWFGEIPHFLDDI
AAAIEGADHFVAIGTSGTVYPAAGLVEGARQAGAVTTLINRDPAENDTMFDHIIAGRAAEAVPAWADRLVDS-------
>tr|A0A0Q6BRA6|A0A0Q6BRA6_9RHIZ NAD-dependent deacylase OS=Methylobacterium sp. Leaf456 GN=ASG52_10740 PE=4 SV=1
-------------------------------------MNIENIFVLTGAGISAESGLGTFRDRGGVWSRFDPMKLATPEAFAADPVLVHDFYNMRRRDA-
-VKAEPNPAHAALARLEAELAGRLFLCTQNVDDLHERAGSREVVHIHGELVRARCTACGASREWREDLSVEPACEKTG---GMRPDVVWFGEMPKHLDAI
EDALLKSDLFVAIGTSGAVYPAAGYAAQAREFGIPTLALNLEAADNAGMFAKTRLGPASETVPAFVADILAG-------
>tr|B0UGE4|B0UGE4_METS4 Silent information regulator protein Sir2 OS=Methylobacterium sp. (strain 4-46) GN=M446_5854 PE=3 SV=1
------------------------------------GRPGVNIFVLTGAGISAESGLGTFRDRGGLWHRFDPARLATPEAFAADPEEVHAFYNLRRRGV-
-REAAPNAAHQALARLEAGLAGRLFLCTQNVDDLHERGGARAVVHMHGEILRARCLACGAEARWEEDLTVDPSCGRGG---GMRPAVVWFGEVPLHLDAV
EEGLAAADRFVAIGTSGAVYPAAGFVARARRRGIPTHEINLEPSDTARTFDSAAYGPATEAVPAFVASVLGG-------
>tr|A0A0J6SLA3|A0A0J6SLA3_9RHIZ NAD-dependent deacetylase OS=Methylobacterium aquaticum GN=VP06_13925 PE=3 SV=1
------------------------------------SPGLRDVFVLTGAGISAESGLGTFRDPDGLWRRFDPMRLATPEAFADAPEEVHAFYNLRRQGA-
-RAAAPNAAHAALVRLEAGLAGRLFLCTQNVDDLHERAGATAVVHMHGELMRARCIACGQGLPWAEDLSVEPACGQRG---GMRPDVVWFGEMPLHLEAI
AQALDTSDLFVAIGTSGAVYPAAGFVARARAAGIPTHEINLAPSDTAGLFAQATYGPATQAVPDFVDGLLQT-------
>tr|A0A061QDA9|A0A061QDA9_9PROT NAD-dependent protein deacylase OS=alpha proteobacterium Q-1 GN=cobB PE=3 SV=1
------------------------------------NSLPRHVVVLTGAGISAESGLGTFRDAGGLWANHRIEDVATPEGFIKNPQLVHYFYNQRRAELQ
R--VAPNAAHHALVDLEAELVGGLTLITQNVDDLHERAGSRSVLHMHGELLKARCEACAAVFPWHRDLGSEIACGHS----SLRPRIVWFGEVPFHLDAI
DAAMARADLFISIGTSGSVYPAAGLVRLARTLGVRTVELNLEPSENHDFFDESHQGPAATIVPAFIADLLAR-------
>tr|A0A0G3CMT7|A0A0G3CMT7_9ENTR NAD-dependent deacetylase OS=Pragia fontium GN=QQ39_08035 PE=3 SV=1
------------------------------------ASHNPSVVVLTGAGISAESGIRTFRASDGLWEDHRIEDVATPEGFEANPELVQAFYNARRRQLI
SPEILPNDAHKALAKLEDLL-NKFLLVTQNVDNLHERAGNMRVIHMHGELLKIRCTRSGKVAEWKGDLSVNYCCEPPQ---PMRPHIVWFGEMPLEMDKI
SQAIAEADYFIAIGTSGHVYPAAGFVRSARLYGAHTVELNLEPSQVANSFEEKHCGLASQVVPEYIQQTFLD-------
>tr|A0A0E3ZNE4|A0A0E3ZNE4_PASMD NAD-dependent deacetylase OS=Pasteurella multocida subsp. multocida OH4807 GN=I926_02850 PE=3 SV=1
------------------------------------MSTYPKIVVLTGAGISAESGIKTFRAANGLWENHRVEDVATPEGFTRHPELVQHFYNERRKQLF
SSQVHPNAAHLALAKLEQKL-KNLLIVTQNVDNLHERAGSKNLIHMHGELLKVRCVKSGKVYDWEKDITSKPCCHPPQ---TLRPHIVWFGEMPLEMDSI
QNALSECDYFIAIGTSGHVYPAAGFVREAAYYGAHTVELNLEPSQARSSFDETHYGKASQIVPRYITQFLSL-------
>tr|A0A085HK37|A0A085HK37_9ENTR SIR2 family NAD-dependent protein deacetylase OS=Leminorella grimontii ATCC 33999 = DSM 5078 GN=GLGR_1508 PE=3 SV=1
------------------------------------ASIYPSVVVLTGAGISAESGIRTFRASDGLWEEHRIEDVATPEGYEANPELVQAFYNARRRQLL
SPNIAPNEAHKALAKLENLL-SKFLLVTQNVDNLHERAGNLRVVHMHGELLKVRCTCSEKVFDWKGDLSVDDCCTPPQ---PMRPHIVWFGEMPLEMGQI
SKALAEADYFIAIGTSGHVYPAAGFVRTASLSGAHTVELNLEPSKVGSSFAETHYGLASQTVPEYVQQTFLD-------
>tr|D4F6Q5|D4F6Q5_EDWTA Transcriptional regulator, Sir2 family OS=Edwardsiella tarda ATCC 23685 GN=EDWATA_02439 PE=3 SV=1
------------------------------------TINRPRVVVLTGAGISAESGIRTFRAADGLWEEHRVEDVATPEGYRRDPELVQAFYNARRRQLQ
TPAIQPNAAHLALARLEQEL-DHFLLVTQNIDNLHERAGNRRVIHMHGELLKARCTQSGQVVKWLGDLSVDHCCQIPA---PLRPHVVWFGEMPLGMDEI
YQALQQADEFIAIGTSGHVYPAAGFVHEARLSGAHTVELNLEPSQVESEFAEKHYGPASQVVPHYLQQLLIR-------
>tr|Q1AWC3|Q1AWC3_RUBXD Silent information regulator protein Sir2 OS=Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) GN=Rxyl_1341 PE=3 SV=1
------------------------------------MRGARGVAALTGSGVSAESGVPTFRDATGLWERFDPEELATPEAFLRDPKLVWEWYSWRRELV-
-ARAEPNPAHRALADLERRV-PSFALITQNVDGLHRRAG--NVIELHGNILRTVCSAER----LP-----EPRCPRCGA--PLRPDVVWFGEALG---AA
SEAARSCEVFLCVGTSGVVYPAAGLPREAAG-GALVVEVNPEP-PVTPLAAFALRGRAGELLPALVAAAFSA-------
>tr|S2ZDM7|S2ZDM7_9CORY Uncharacterized protein OS=Corynebacterium pyruviciproducens ATCC BAA-1742 GN=HMPREF1219_02496 PE=4 SV=1
---------------------------------------MGNIVFFTGAGMSADSGLETYRDKTGLWENVDPNALASIDSWAKDPEPMFAHYTWRSIVS-
-NSVQPNAGHQAIGA------AHLPVITQNIDNLHERGG--EVVHLHGSLFKWKCTICGRPYKYTLPE--RPECPLCHN--PIRPEVTWFGEALQ---RA
VELLQDCDTLVIVGTSGTVQPAASLPLVALD-GARLYEVSPQP-TLTPLVHEYISATAATGVPALLEKLL---------
>tr|C2GEX8|C2GEX8_9CORY Transcriptional regulator, Sir2 family OS=Corynebacterium glucuronolyticum ATCC 51866 GN=HMPREF0293_0471 PE=4 SV=1
---------------------------------------MGKIVFFTGAGMSADSGLETYRDKTGLWEKVDPMALASIDSWAKDPDPMFAHYTWRSIAS-
-NNATPNAGHKAIGT------LGAPVITQNIDNLHERGG--EVVHLHGSLFKWKCTICGRPYSYTLPE--RPSCPLCGN--PIRPEITWFGEALK---RA
VELLQDCDVLVIVGTSGTVQPAASLPLVALE-GARLYEISPQP-SLTPLVHEFIEDTAASGVPALLERL----------
>tr|A0A0F4EQ75|A0A0F4EQ75_9MYCO NAD-dependent deacetylase OS=Mycobacterium lepromatosis GN=npdA PE=3 SV=1
----------------------------------------MRVAVLSGAGISAESDVPTFRDDNGLWARFDPYQLSSTQGWQSNPARVWGWYLWRHYLV-
-ANVKPNDGHRAIAAWQEQI----SVITQNVDDLHERAG--PVHHLHGSLFKFHCARCSVAYTGALPE--EPVC-YCGG--LIRPAIVWFGEPLE---RA
VEATKATDVMVVVGTSAIVYPAAGLPELALS-GAVLIEVNPEP-PLTKNATISIRETASQALPGLLQRLPAL-------
>tr|A0A0I9YXL0|A0A0I9YXL0_9MYCO NAD-dependent deacetylase OS=Mycobacterium nebraskense GN=ABW17_07005 PE=3 SV=1
----------------------------------------MRVTVLSGAGISAESGVPTFRDDNGLWAHFDPYELSSTQGWRDNPERVWGWYLWRHYLV-
-ADVQPNAGHRAIAAWQDGA----SVITQNVDDLHERAG--PVHHLHGSLFEFRCDRCGMPYTGRLPE--EPVC-QCGG--LIRPDIVWFGEQLA---SA
VEATEAADVMVVVGTSAIVYPAAGLAELALS-GTVVIEVNPEV-PLSRNATISIRETAGQALPGLLQRLPAL-------
>tr|I0RUP4|I0RUP4_MYCXE NAD-dependent deacetylase OS=Mycobacterium xenopi RIVM700367 GN=MXEN_08322 PE=3 SV=1
----------------------------------------MRITVLSGAGISAESGVPTFRDDNGLWARFDPYELASIDGWLQNPDRVWGWYLWRHYLA-
-SCVEPNAGHRAIAGWQDHA----TVVTQNVDNLHERAG--PVHHVHGSIFEFRCASCALPYTGKLLE--EPTC-GCGG--LIRPDVVWFGEPLE---RA
VEATQAADVLVVVGTSAIVYPAASLPELALA-GATVVEVNPEP-PLSGSATISLRETASQALPGLLQRLPAL-------
>tr|A0A0H3M9N7|A0A0H3M9N7_MYCBP Probable transcriptional regulatory protein OS=Mycobacterium bovis (strain BCG / Pasteur 1173P2) GN=BCG_1212c PE=3 SV=1
----------------------------------------MRVAVLSGAGISAESGVPTFRDDNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLV-
-ANVEPNDGHRAIAAWQDHA----SVITQNVDDLHERAG--AVHHLHGSLFEFRCARCGVPYTDALPE--EPVC-DCGG--LIRPDIVWFGEPLE---SA
VEATGSADVMVVVGTSAIVYPAAGLPDLALA-GTAVIEVNPEP-PLSGSATISIRESASQALPGLLERLPAL-------
>tr|B2HSD0|B2HSD0_MYCMM Transcriptional regulatory protein OS=Mycobacterium marinum (strain ATCC BAA-535 / M) GN=MMAR_4302 PE=3 SV=1
----------------------------------------MRVTVLSGAGISAESGVPTFRDDNGLWARFDPYELSSTQGWERNPERVWGWYLWRHYLV-
-ADVAPNPGHQAIAEWQDHA----SVVTQNVDDLHERAG--PVHHLHGSLFEFRCARCNKPYTDSLPQ--EPVC-GCGG--LIRPDIVWFGEPLG---CA
VEATEAADVMVVVGTSAIVYPAAGLPELALA-GKIVIEVNPEP-PLSRSATLCVRESASQALPGLLERLPAL-------
>tr|V7L855|V7L855_MYCAV NAD-dependent deacetylase OS=Mycobacterium avium subsp. avium 10-9275 GN=O972_06410 PE=3 SV=1
----------------------------------------MRIAVLSGAGISAESGVPTFRDDNGLWARFDPYELSSTQGWRDNPQRVWGWYLWRHYLV-
-ADVAPNAGHRAIAAWQDHA----SVITQNVDDLHERAG--PVHHLHGSLFEFRCARCAKPYTGELPA--EPVC-GCGG--LIRPDIVWFGEQLE---RA
VEATESADVVVVVGTSAIVYPAAGLAELALS-GAAVVEVNPEV-PLSASATLSIRETASQALPGLLQRLPAL-------
>tr|A0A0M2JVQ1|A0A0M2JVQ1_9MYCO NAD-dependent deacetylase OS=Mycobacterium obuense GN=WN67_17620 PE=3 SV=1
----------------------------------------MQVTVFSGAGISAESGVPTFRDVTGLWAQVDPYEISSSEGWQAHPDRVWAWYLWRHHMM-
-AAVEPNDAHRAVAAWQDYA----HVVTQNVDDLHERAG--QVYHVHGSLFEFHCDRCGTAYPGEVPD--SPRCGVCGG--LIRPNVVWFGESLR---QS
VDAVVGADVVVVVGTSSVVYPAAGLPELAVA-GTPVIEINPEP-PLSRSATVSLREKAGTALPGLLQRLPAL-------
>tr|L0J2V3|L0J2V3_MYCSM NAD-dependent protein deacetylase, SIR2 family OS=Mycobacterium smegmatis JS623 GN=Mycsm_04966 PE=3 SV=1
--------------------------------------------MLSGAGISAESGVPTFRDATGLWAKVDPYEISSAEGWHDHPDKVWAWYLWRHQMM-
-GSVQPNDGHLAVAAWQDYA----HVVTQNVDNLHERAG--RVYHLHGSLFEFRCDRCGREYLDELPT--SPRC-ACGG--LIRPNVVWFGEALE---RS
LDAVTTADLVIVVGTSSIVYPAAGLPELALA-GTVVIEVNPER-PLSDAATAVVRESAATALPSLLQRLPAL-------
>tr|A0A0J6WLT8|A0A0J6WLT8_9MYCO NAD-dependent protein deacylase OS=Mycobacterium chubuense GN=cobB_1 PE=3 SV=1
------------------------------------------MTVFSGAGISAESGVPTFRDVTGLWAEVDPYEISSADGWRSHPDRVWAWYLWRHHMM-
-GAVAPNNAHRAVAAWEDYA----HVVTQNVDNLHERAG--QVYHVHGSLFEFHCDRCGAAYLGEVPA--SPRC-VCGG--LIRPNVVWFGEALR---QS
VDAVINADVVVVVGTSSVVYPAAGLPELAVA-GTPVIEVNPEP-PLTSTATVSLREKAGAALPGLLQRLPAL-------
>tr|A1TDU5|A1TDU5_MYCVP Silent information regulator protein Sir2 OS=Mycobacterium vanbaalenii (strain DSM 7251 / PYR-1) GN=Mvan_4570 PE=3 SV=1
------------------------------------------MTVFSGAGMSAESGVPTFRDVTGLWAKVDPYEISSADGWRAHPDRVWAWYLWRHHMM-
-SAVAPNNAHRAVAAWEDYA----HVVTQNVDNLHERAG--RVYHVHGSLFEFHCDRCRSTFPDKVPD--SPSCGECGG--LIRPNVVWFGEPLD---RS
VDAVVNADLVVVVGTSSVVYPAAGLPELAIA-GTPVIEVNPEP-PLTASATVSLRETAATALPGLLQRLPAL-------
>tr|A4T935|A4T935_MYCGI Silent information regulator protein Sir2 OS=Mycobacterium gilvum (strain PYR-GCK) GN=Mflv_2134 PE=3 SV=1
------------------------------------------MTVFSGAGISAESGVPTFRDVTGLWAKVDPYEISSADGWRAHPDRVWAWYLWRHHMM-
-SAVGPNNAHRAVAAWEDYA----HVVTQNVDNLHERAG--RVYHVHGSLFDFHCDTCRSAYRGPVPD--SPVCEACGG--LIRPDVVWFGEALD---RS
VEAVAGADLVVVVGTSSVVYPAAGLPEMALA-GTPVIEVNPEP-PLSSSATVTLREKASTALPGLLQRLPAL-------
>tr|G8RTE3|G8RTE3_MYCRN NAD-dependent protein deacetylase, SIR2 family OS=Mycobacterium rhodesiae (strain NBB3) GN=MycrhN_3612 PE=3 SV=1
----------------------------------------MQIAVLSGAGISAESGVPTFRDATGLWAKVDPYEISSSEGWRSHPERVWAWYLWRHYMM-
-GSVAPNDGHRAVAAWEDYA----HVVTQNVDNLHERAG--NVSHLHGSLFEFRCDRCHTAYTGELPA--TPRC-ACGG--LIRPNVVWFGEGLD---RS
VEAVAGADLVIVVGTSSIVYPAAGLPEMAVA-GTVVIEVNPEP-PLSATATVSLRETAAVALPSLLQRLPVL-------
>tr|K0UC35|K0UC35_MYCVA NAD-dependent deacetylase OS=Mycobacterium vaccae ATCC 25954 GN=MVAC_27174 PE=3 SV=1
----------------------------------------MQVTVFSGAGISAESGVPTFRDVTGLWAKVDPYEISSAEGWRAHPDRVWAWYLWRHHMM-
-SAVAPNNAHRAVAAWQDYA----HVVTQNVDNLHERAG--RVHHVHGSLFEFHCDRCGSAYTGEVPE--SPTCAKCGG--LIRPNVVWFGEALD---MS
VAAVVNADLVVVVGTSSVVYPAAGLPELAVA-GTPVIEVNPEP-PLSASATVTLREKAAAALPGLLQRLPAL-------
>tr|W4HY47|W4HY47_MYCGS NAD-dependent deacetylase OS=Mycobacterium gastri 'Wayne' GN=MGAST_11950 PE=3 SV=1
----------------------------------------MRVTVLSGAGISAESGVPTFRDDNGLWARFDPYELSSTQGWESNPERVWGWYLWRHYLV-
-ATVEPNEGHRAIADWQSAA----TVVTQNVDDLHERAG--PVHHLHGSLFEFRCARCGMPYTEALPV--EPVC-RCGG--LIRPDIVWFGEALG---HA
VEATEAADVMVVVGTSAIVYPAAGLPELALA-GIPVIEVNPEP-PLSGSATICVRQSASRALPRLLQRLPSL-------
>tr|F5YV84|F5YV84_MYCSD Transcriptional regulatory protein OS=Mycobacterium sinense (strain JDM601) GN=JDM601_1137 PE=3 SV=1
----------------------------------------MQVAVFSGAGISAESGVPTFRDDKGLWSQYDPYEVSSIDGWNRQPELVWGWYLWRCQLA-
-RRVEPNLGHRAVADWEQHA----HVITQNVDNLHERGG--RVHHLHGRMFTFRCGDCDQPQDPEVPV--EPVC-ECGG--LVRPDVVWFGENLE---AA
VEAIDNADVLIVVGTSGVVYPAAGLPERALE-GKVVIEVNPEP-PLSERATTYLRTTASAALPGMVQRLPFL-------
>tr|A0A0I9TRP9|A0A0I9TRP9_9MYCO NAD-dependent deacetylase OS=Mycobacterium heraklionense GN=ABW16_00490 PE=3 SV=1
----------------------------------------MRVVVFSGAGISAESGIPTFRDDKGLWSQYDPYEVSSIDGWNRQPELVWGWYVWRCQLA-
-RRYEPNLGHTAIADWEQHV----QVITQNVDNLHERGG--TVHHLHGRMFTFRCSDCEQPHDTQLPE--EPQC-ECGG--LIRPDVVWFGEQLE---AA
VEAIDAADALIVVGTSGVVYPAASLPERALE-GKTVIQVNPEP-PLSERATVFLRTTASAALPGMAQRLPFL-------
>tr|A0A0Q2R8D1|A0A0Q2R8D1_MYCGO NAD-dependent deacetylase OS=Mycobacterium gordonae GN=AO501_28970 PE=4 SV=1
----------------------------------------MRVTVLSGAGISAESGVPTFRDDNGLWAQFDPYELSSVQGWERNPERVWGWYLWRHYLV-
-ADVQPNAGHQAIADWQRHP-TSVTVITQNVDDLHERAG--PVHHLHGSLFEFRCARCGLPYAEALPV--EPVC-HCGG--LIRPDIVWFGEALG---SA
LDATENADVVVVVGTSSIVYPAAGLPELALA-GTAVIEVNPEA-PLSQHATLCVRESASQALPGLLERLPAL-------
>tr|G4I4Z9|G4I4Z9_MYCRH NAD-dependent deacetylase OS=Mycobacterium rhodesiae JS60 GN=MycrhDRAFT_5378 PE=3 SV=1
--------------------------------------------MLSGAGISAESGVPTFRDDTGLWAKYDPYELSSTDGWQSHPERVWAWYLWRHHLV-
-ERVEPNDGHRAVAAWQDYA----TVVTQNVDDLHERAG--TVHHLHGSLFEFWCDTCGSRYHGPLPD--EPRC-ECGG--LIRPGIVWFGEQLE---AS
VEAVANADVLVVVGTSGIVYPAAGLPEVALA-GIVVVEVNPEP-PLTGNATISIRESASSALPRLLQRLPEL-------
>tr|A0A064CQ87|A0A064CQ87_9MYCO NAD-dependent deacetylase OS=Mycobacterium aromaticivorans JS19b1 = JCM 16368 GN=Y900_019160 PE=3 SV=1
----------------------------------------MRIAVLSGAGISAESGVPTFRDDTGLWAKYDPYELSSTDGWQNHPERVWAWYLWRHHLV-
-QQVEPNDGHRAVAAWQDYA----SVITQNVDNLHERAG--PVHHLHGSLFEFWCDTCGSRYHGPLPD--EPHC-ECGG--LVRPGIVWFGEQLE---AA
VEAVATSDVLVVVGTSGIVYPAAGLPDVALA-GAVVVEVNPEP-PLSANATLTIRESASTALPTLLQQLPEL-------
>tr|A0A0K1PY88|A0A0K1PY88_9DELT NAD-dependent protein deacetylase of SIR2 family OS=Labilithrix luteola GN=AKJ09_05159 PE=4 SV=1
------------------------------------FADFQRIVFFTGAGLSAESGIPTYRGK-GIWTEYNYEDYACQRAFERNPNKVWDFHDKRRGFV-
-AEREPNQGHSIIAELQR-S-PDTAVITQNIDGLHGLAVG-PIVELHGSLWRVRCD-EGTVRPDRS----VPRTCSCGA--YFRPDIVWFEDMLR---RA
HELLQRCDLLVSVGTSGVVYPAADMPRIAMS-GAVTVEINLED-PVSSSYQHRLRGKASDILAAMSI------------
>tr|B3QNG5|B3QNG5_CHLP8 Silent information regulator protein Sir2 OS=Chlorobaculum parvum (strain NCIB 8327) GN=Cpar_1060 PE=4 SV=1
------------------------------------PTAYQRIVFFTGAGMSAESGIPTYRGK-GFWSQCDYEEYACQEAFERQPEKVLHFHELRRQAV-
-LDCEPHEGHRVISGM-----PETFVITQNIDGMHQRAG--KVIELHGSLWQLRCE-CETMKEDFG----RTLRCDCGC--WLRPAITWFGDRLV---QA
SEIIASCDLFISIGTSGTVWPAAGFPELARQ-GAYCIEINPEP-G-ATSYHQTIRGKAGRVLPELFARET---------
>tr|B3EMB2|B3EMB2_CHLPB Silent information regulator protein Sir2 OS=Chlorobium phaeobacteroides (strain BS1) GN=Cphamn1_0527 PE=4 SV=1
------------------------------------PATYREIVFFTGAGMSAESGVPTYRGK-GIWGSYSIDEYACQEAFDRNPEKVLGFHEKRRKSV-
-LDCQPHEGHSVVAVL-----PNAKVVTQNIDGMHQRAG--DVIELHGSLWRLRCQ-CGFRKEDLA----ETTRCDCGD--RLRPDIIWFGDMLV---KA
SQAIRNCDLFVSIGTSGTVWPAAGFPDLAKQ-GAYCIEINPEP-G-ASEYDRVIVGNAGEVLPELFSES----------
>tr|Q0A705|Q0A705_ALKEH Silent information regulator protein Sir2 OS=Alkalilimnicola ehrlichii (strain ATCC BAA-1101 / DSM 17681 / MLHE-1) GN=Mlg_2040 
------------------------------------LRGARRPVVLTGAGMSAESGVPTFREA-GLWARFDPVELATPEAFERHPQRVLDWYAWRREQV-
-AKARPHAGHQALARWEA---AALVIVTQNVDGLHQRAG--NVVELHGRIDRDRCHHCGE-------R--ERVCAQCGG--PLRPDVVWFGEMLP---RA
LGAVSEADLVLSVGTSTLVQPAASLPAEALA-GVPVVEINPEP-PLKGRTLYRLRGKAAEWLPRLVAIACD--------
>tr|A0A0E4CPX6|A0A0E4CPX6_9MYCO Transcriptional regulator OS=Mycobacterium lentiflavum GN=BN1232_04605 PE=3 SV=1
------------------------------------MLVAMRVTVLSGAGISAESGVPTFRDDNGLWARFDPYELSSTQGWLNNPERVWGWYLWRHYLV-
-GTVEPNDGHRAIAAWQDYA----SVITQNVDDLHERAG--PVHHLHGSLFEFRCTSCDLPYHDTLPE--EPLCPRCGG--LIRPDIVWFGEQLG---HA
VEATQAADVMVVVGTSAIVYPAAGLADLALS-GVTVIEVNPEP-PLSGSVTLSIRESASQALPGLLQKLPAL-------
>tr|M6D2R8|M6D2R8_9LEPT Transcriptional regulator, Sir2 family OS=Leptospira sp. B5-022 GN=LEP1GSC192_0138 PE=3 SV=1
------------------------------------FKNSKNILALTGAGISAESGVPTFRGK-GLWKQYRAEDLATPQAFRKDPKLVWEWYLWRMELI-
-STKSPNPAHFALAELEKK--SDFYLITQNVDGLHKKSG--KVMEIHGNIFRNRCISCAHFYDSDL----LIECANCGN--LVRPDVLWFGESYE---QA
VSLAERSELALVIGSSGAVGIPVELARIAKE-GAFVIEINLDP-GYSRYADLFLQGKAGEILPEIVSYFV---------
>tr|A0A0E3B7U2|A0A0E3B7U2_LEPBO NAD-dependent protein deacylase OS=Leptospira borgpetersenii serovar Ballum GN=IQ66_09855 PE=3 SV=1
------------------------------------KGKFQRITAISGAGISAESGIPTFRGS-GLWKNFRAEDLATPQAFQKDPKLVWEWYLWRRNII-
-DTKQPNRGHLALAELEKI--PDFFLVTQNVDGLHIRAG--KLLEMHGNIFINRCTSCSQESNEKI----GPKCKFCGN--FLRPGIVWFGESYE---FS
IQRMENTNLLLVLGTSGLVSMPVYLTQVAKR-GAILIEVNPER-SFSSSVDLFIQGKTGEILPELVSEIVA--------
>tr|A0A0F6TPC6|A0A0F6TPC6_9GAMM NAD-dependent protein deacetylase OS=Kangiella geojedonensis GN=TQ33_0388 PE=4 SV=1
------------------------------------IQRAKRVTILTGAGVSAESGVATFRSY-SLWSQYDPQKMASIHGFLENPNRVWQWYQWRRSEL-
-KNKSPNDAHKAIAKWQQSN-QNVTLITQNVDGLHQAGG--EIIELHGNIWRNHCL-CREDYKGDV-----IDCPECGG--QIRPSVVWFGEALH---DA
ESASYSCDLFLSVGTSSQVYPAAGLAALAKS-GATVVEINPEP-EGL-VVDYTIPVVASQFFGGLS-------------
>tr|A9AWG1|A9AWG1_HERA2 Silent information regulator protein Sir2 OS=Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785) GN=Haur_4088 PE=4 SV=1
------------------------------------LRRYRNIVVLTGAGISVASGVRPFRGP-GVWNEWDIERCATRTALEQSPQLVWQAFGPLRSQL-
-QTTQPNAAHRALARFEQSL-QRFTLITQNIDGLHQLAG--NLVEFHGSLRQSRCSDCDQPSFVDQ----TPLCPTCGK--PLRPDIVLFEEAIW---QA
KRSLRECDFFLAVGTSGTVFPAAAFARTAQM-GARTMLVNLEPAADDSAFEEQQIGRAEELLPTLLGVA----------
>tr|A0A084SVR5|A0A084SVR5_9DELT Sir2 family transcriptional regulator OS=Cystobacter violaceus Cb vi76 GN=Q664_14750 PE=4 SV=1
------------------------------------AASWRHVVVLTGAGISVASGLPTYRGP-GLWTRPDLEEIPDAGMLARDVSRVWSLFGPLREQV-
-RTAAPNAAHLALAGWEGRC-GSFTLLTQNVDGLHSRAG--EVVELHGSLRRTRCTNCTLAPFEDS----TPVCTLCGE--PLRPDITLFDEPLD---KA
KHALRECDLFLAVGTSGTVSPASNFVRGAKY-GARTLLVNLTPRPRHPDFDVELLGHAEHILPLLLGER----------
>tr|B0C4H8|B0C4H8_ACAM1 Transcriptional regulator, Sir2 family protein OS=Acaryochloris marina (strain MBIC 11017) GN=AM1_3731 PE=4 SV=1
------------------------------------LAAYSRIVILTGAGISVASGIRPFRGP-GVWNEISADQLN-AEAGQNNPGFIWQTLGAMRKVV-
-ASAAPNAAHQALADLEQNL-QQFTLITQNIDGLHQRAG--NVVELHGSLLETRCSNCDAPVFADQ----APQCSVCHA--HQLPNVVLFEEPID---QS
KKALRDCDLFLAIGTSGTVQPAASFVRSADY-GAHTILINLEASEPNPYFHEVIVGAAEEILPTLLK------------
>tr|M3FLW9|M3FLW9_9LEPT Transcriptional regulator, Sir2 family OS=Leptospira weilii serovar Topaz str. LT2116 GN=LEP1GSC188_4916 PE=3 SV=1
------------------------------------KGKFQRITAISGAGVSAESGIPTFRGS-GLWKNFRAEDLATPQAFQKDPQLVWEWYLWRRNVI-
-SAKQPNRGHLALAELEEM--SDFFLVTQNVDGLHIRAG--KLIEMHGNIFTNRCVSCRQEFNEKI----DPRCEFCGN--FLRPGVVWFGESYE---FS
IQRMENTDLLLILGTSGLVSIPVYLTQVAKR-GSILIEVNPER-SFSSSVDLFVQGKAGEILPELISEIVAI-------
>tr|N1WT85|N1WT85_9LEPT Transcriptional regulator, Sir2 family OS=Leptospira weilii serovar Ranarum str. ICFT GN=LEP1GSC060_0923 PE=3 SV=1
------------------------------------KHRFQKITAITGAGISAESGIPTFRGA-GLWKNFRAEDLATPQAFQKNPELVWEWYLWRRGVI-
-ESKDPNLGHVALAELEKR--TDFFLITQNVDGLHSRAG--KLIEIHGNIFLNCCSFCENKILINV----NPKCNLCGS--LFRPGVVWFGESYS---QC
IERMKNTDLLLIIGTSGAVSMPVYLAEIAQE-GALLIEINPEK-SFSSSVDLFLKGKSGEILPELVNEIIQI-------
>tr|M6D554|M6D554_9LEPT Transcriptional regulator, Sir2 family OS=Leptospira alstonii serovar Sichuan str. 79601 GN=LEP1GSC194_1719 PE=3 SV=1
------------------------------------KHHFQKITAITGAGISAESGIPTFRGA-GLWKNFRAEDLATPQAFQKNPKLVWEWYLWRRGII-
-ETKDPNSGHEALAELEKR--TDFFLITQNVDGLHSRAG--KLIEIHGNIFINRCSSCDNEILIPI----NPKCNVCGS--LFRPGVVWFGESYS---QS
ILRMRNTDLLLIIGTSGAVSMPVYLAEIAKE-GSIIIEINPEE-SFTPSVDLFLKGKSGEILPDLIHEIISI-------
>tr|M1WJX4|M1WJX4_DESPC NAD-dependent deacetylase 1 OS=Desulfovibrio piezophilus (strain DSM 21447 / JCM 15486 / C1TLV30) GN=npdA PE=3 SV=1
------------------------------------LSGSRRTVVLTGAGISVESGVPTFRGR-GSWKNYRPEDLARPDAFEARPELVWEFYNWRRESL-
-RESEPNAAHLALAEMER---N-FLLITQNVDGLHCRAG--KIMEMHGSLWQIKCTKCTHAREDF-SP--PPECPVCGH--LLRPGVVWFGEPLG---VA
IDEINKSDVFLAVETSSLAQPAASFYQLAKD-GAVTVEINREP-PISGFMDFALHGKASDILPELMAGLSE--------
>tr|B9XDQ7|B9XDQ7_PEDPL Silent information regulator protein Sir2 OS=Pedosphaera parvula (strain Ellin514) GN=Cflav_PD6478 PE=3 SV=1
------------------------------------LRSANRVVVLTGAGVSAESGVPTFRDA-GLWSQYSPEELATPRAFRQNPKLVWEWYQWRRELV-
-SKAKPNPAHYALVEMQE---PEFTLITQNVDGLHRLPG--IIIELHGNIHRTKCFQEGT-------IV-GPKCPDCGG--WLRPDVVWFEEPLA---SA
MKASRKADVFFSIGTSGLVYPAASLPHEALN-NATLVEINPAP-PLTPKADFMLKGPAGVILPELVKALRK--------
>tr|A0A0D6S2V5|A0A0D6S2V5_9PSED NAD-dependent protein deacetylase of SIR2 family OS=Pseudomonas sp. FeS53a GN=SZ55_4762 PE=3 SV=1
------------------------------------LARSQRLVIFTGAGVSAESGIPTFREATGLWARYNPEQLASPDGFRAGPQLVWDWYAWRRQRC-
-LEAQPNPAHRAIAALQQRL-PGTELITQNVDGLHARAG--GLLELHGNIHQLHCFRCGAKGGEWP----EVPHCACGG--LLRPSVVWFGENLP---KA
VQASEAADLFLSIGTSSLVYPAAELPYLARH-GAYLVEVNPQP-PLSAHADLCLHGPAGEVLPALLASLDQL-------
>tr|A0A0E2ID22|A0A0E2ID22_9LEPT Transcriptional regulator, Sir2 family OS=Leptospira kirschneri serovar Cynopteri str. 3522 CT GN=LEP1GSC049_2232 PE=3 SV=1
------------------------------------KNKLRKISAISGAGISAESGIPTFRGK-GLWKNFRAEDLATPQAFSKNPKLVWEWYLWRRNII-
-KTKRPNPGHFALAELERI--PDFFLITQNVDGLHSQAG--KLTEIHGNIFINRCISCGQESKEKI----TPQCQNCNS--FLRPGVVWFGESYP---LS
IQRMKHTDLLLVLGTSGSVSMPVYLSQIAKD-GALLVEINPEL-SFSSSVDLFLQGKTGEVLPELIREILDN-------
>tr|I0XLW5|I0XLW5_9LEPT Transcriptional regulator, Sir2 family OS=Leptospira licerasiae serovar Varillal str. VAR 010 GN=LEP1GSC185_2873 PE=3 SV=1
------------------------------------FKNSKNILALTGAGISAESGVPTFRGK-GLWKQYRAEELATPQAFHRDPGLVWEWYIWRMELI-
-STKSPNPAHYALVELEKK--SNFHLITQNVDGLHKKSG--KIIEIHGNIFRNKCVRCAKMYESVI----LTECPNCKS--LVRPDVLWFGENYD---RA
IFLAERSEIVFVIGSSGAVGIPVELARVAKE-DAFVVEINIDP-GYSRYADLFLQGKAGEILPELIHYFS---------
>tr|S3V784|S3V784_9LEPT Transcriptional regulator, Sir2 family OS=Leptospira wolffii serovar Khorat str. Khorat-H2 GN=LEP1GSC061_0573 PE=3 SV=1
------------------------------------LKSSKRILALTGAGISAESGVPTFRGK-GLWKNFRAEELATPEAFRKNPKLVWEWYLWRMELI-
-SQKEPNPAHKVLAELEE---G-FRLVTQNVDGLHRKAG--RLLEIHGNIFRNRCISCNHQSETILP---GPLCDHCGG--SLRPGVLWFGESYD---ES
VKYAESAEVTLVIGSSGMVGIPVELARIARE-GSLVIEINTEE-GYSRHADLFLQGKAGEILPALASYFP---------
>tr|M6ZPC9|M6ZPC9_9LEPT Transcriptional regulator, Sir2 family OS=Leptospira santarosai str. 200702252 GN=LEP1GSC120_3285 PE=3 SV=1
------------------------------------KNKFRRITAISGAGVSSESGIPTFRGN-GLWKNFRAEDLATPQAFRKDPKLVWEWYLWRRNVI-
-DTKLPNRGHLALAKLEEI--PDFFLITQNVDGLHIRAG--KLLEMHGNIFINRCTACGQESKEKI----NPKCELCGS--FLRPGVVWFGESYK---FS
IQRMENTDLLLILGTSGSVSMPVYLTQVAKR-GSILVEVNPEL-SLSSSVDFFIQGKTGEILPELTREILKA-------
>tr|A0A0K2X0P3|A0A0K2X0P3_CORST NAD-dependent protein deacylase 2 OS=Corynebacterium striatum GN=cobB PE=3 SV=1
------------------------------------IKNAHRIEIFTGAGMSADSGLATYRDPSGIWENVDPQDMASIDAWAKDPIRMWRWYAHRRHQA-
-EKAQPNAGHIALAQWDK----EVTVTTQNIDDLHERAG--DVVHLHGSLFAFRCCMCGRPWRGGVD---TPKCPLCGN--LVRPGVVWFGEALR---EA
EKRMAAADLVIIVGTSGVVYPAAGLPRIAHR-GTPIIEVSPQS-DLTSLSTVFINSTAADALPKLAKL-----------
>tr|A0A068JG64|A0A068JG64_9DELT NAD-dependent deacetylase OS=Desulfonatronum thiodismutans GN=GY33_00515 PE=4 SV=1
------------------------------------WRSAHRVVALTGAGISVPSGIPDFRS--GLWSRFDANVVASTWGLERNPKAVWEFLLDALTMF-
-GNASPNPAHLALTRLEQA--RLDMVITQNIDGLHQQAG--NVIEFHGNCRGFYCN-CRRDYPAEA-A--TWLCEACGE--VIRPTLVFFGEAIA---ES
QRWSNRADLAVIIGTSGDVAPANIIPYQVKA-GGRVVEINLGP-SYGDLADVRLDLPAEACLPELAERLG---------
>tr|A7NJL6|A7NJL6_ROSCS Silent information regulator protein Sir2 OS=Roseiflexus castenholzii (strain DSM 13941 / HLO8) GN=Rcas_1593 PE=3 SV=1
------------------------------------MRTARRVAVLTGAGVSAESGVPTFRDA-GLWARYDPAELASPDAFRANPNLVWQWYAYRRALV-
-EAAAPNPGHLALADLER---EDFTLITQNVDGLHRRAG--NVVELHGNLFRYRCFHCAA-------PV-QPPCPRCGG--LVRPDVVWFGEWLQ---TA
VAAAERCELFLCIGTSGVVRPAADLPLIARS-GAYAVEINIAP-ALDDRLDLHLYAPSGQLLPALMTAAFGD-------
>tr|A5USR2|A5USR2_ROSS1 Silent information regulator protein Sir2 OS=Roseiflexus sp. (strain RS-1) GN=RoseRS_1260 PE=3 SV=1
------------------------------------LRKARCVAVLTGAGVSAESGVPTFRNA-GLWARYDPGELASPAAFRANPALVWQWYAYRRSLV-
-AAAEPNPGHIALAELER---ADFTLITQNVDGLHHRAG--NVVELHGNLNRYRCFADDE-------PV-QPPCPRCGG--LVRPDVVWFGELLR---VA
VAAARRCELFLCVGTSGVVHPAADLPLIARS-GAYTVEINIAP-ALNGLLDLHLYAPSGHMLPALAAAAFGN-------
>tr|A0A089LNM3|A0A089LNM3_9BACL NAD-dependent deacetylase OS=Paenibacillus stellifer GN=PSTEL_04345 PE=4 SV=1
------------------------------------ISSSKHTVVLSGAGMSTESGLPDFRSRDGWWRNMDPHKVANVTAIEENYELFWGFYKYRIETV-
-EQYSPHIGHHILAKWEK---WIHGISTQNVDGYHVVAG-HNIVELHGNIRSIRCHYCGRSSDV------RLNCSSCQG--PLRPNVVLFGEMLNAWNQA
FQWFHRAELVLVIGTSLQVAPANQLPCLTS---GHTVYMNMEE--LDPSFDLMIKGKVGQLLAELDEMLDYI-------
>tr|A0A0A3I211|A0A0A3I211_9BACI NAD-dependent deacetylase OS=Lysinibacillus manganicus DSM 26584 GN=CD29_09160 PE=4 SV=1
------------------------------------LKSSTSTIVLTGAGMSTESGIPDFRSQSGWWNKIDPRTVATVEALENHYALFHDFYSYRIQSL-
-EKYTPHEGHYILGQWEN---VLDCVATQNVDGFHQLAG-RKVNELHGTIKTIRCHSCNQPATL------KEVCKHCSG--KLRPNVVLFGETLHSWMDS
LNRIRRADLVIVIGTSLEIYPVSQLPVMTE---GKKVYVNLDD----ARFDLMIKGKAKEILKLVNNIL----------
>tr|A0A0B1Y8G6|A0A0B1Y8G6_9BACI NAD-dependent deacetylase OS=Lysinibacillus sp. A1 GN=PI85_08165 PE=4 SV=1
------------------------------------LQSSKNTVILTGAGMSTESGIPDFRSVSGWWNHIDPRTVATTEALTENYALFHEFYKLRIETL-
-DKAAPHEGHSILADWEQ---IVSLVATQNVDGFHQLAG-QNVEELHGSIRSIRCHRCQQAAFI------KASCPQCGG--TLRPNVVLFGESLKSWHIV
MEAIKRAELVLVIGTSLEVYPVNQLPMMTK---GKTVYINLDQ---TVPFDLVIEGKIKEVLQQIPI------------
>tr|A0A0J6NMF5|A0A0J6NMF5_9BACI NAD-dependent deacetylase OS=Lysinibacillus sp. LK3 GN=VK91_10455 PE=4 SV=1
------------------------------------LLSSNNTVILTGAGMSTESGVPDFRSASGWWKQMDPRTVATTEALTDHYSLFHEFYKTRIENL-
-EKVAPHEGHHLLADWER---LVSLIATQNVDGFHQLAG-QSVEELHGSIRSIRCHRCQQAAVM------KASCAHCGG--KLRPNVVLFGESLASWHCS
MEAIKTAELVLVIGTSLEVYPVNQLPMMTT---GKTVYVNMDQ---TTPFDLTVRGKIKEVLQKLQI------------
>tr|D6XZ51|D6XZ51_BACIE Silent information regulator protein Sir2 OS=Bacillus selenitireducens (strain ATCC 700615 / DSM 15326 / MLS10) GN=Bsel_2845 PE
------------------------------------LKTADSVVVLTGAGMSTESNIPDFRS--GWWQQVDPMTIATPEALEGNPEQFKAFYKARLEAL-
-EEAEPNRGHQIIARWEER--LVDRVATQNVDGLHQRAG--NVDALHGTIHAIRCH-CDRPHELDA-F---EACVSCGG--VLRPGVVLFGEMLD---RA
LKAIEKADVVLVIGTSLDVYPVNQLPSV----GGKTVYINRDI-QSIHAFDAVHQGSAGEILEELDRLMEA--------
>tr|K1LHQ3|K1LHQ3_9BACI NAD-dependent deacetylase OS=Bacillus isronensis B3W22 GN=cobB_2 PE=4 SV=1
------------------------------------MKQSNRTVVLTGAGMSTESGIPDFRSSTGLWRNINPRIVASTESLQKNYEQFREFYQTRMNSL-
-NNCKPHEGHLILADFEK---LVSLIATQNVDQLHQQAG-KNVAELHGNIVTIRCQKCGKPHAK------NSICTYCSG--KLRPNVVLFGETLEAWDRT
LHEIHQADLVIVIGTSLEVYPVNQLPSMSK---GKLVYINRES-SLHYSFDLVLEGSAGKILADVYQELGDF-------
>tr|W9BIT0|W9BIT0_9MYCO NAD-dependent protein deacetylase, SIR2 family OS=Mycobacterium cosmeticum GN=BN977_01508 PE=3 SV=1
------------------------------------YFGGVQVTVLSGAGMSAESGVPTFRDVTGLWAKVDPYEISSSEGWQRHPEKVWAWYLWRHYLM-
-DAVQPNNGHRAVAAWEDYA----HIATQNVDNLHERAG--RVHHLHGSLFEFRCDRCQMPFTGELPT--VPRC-GCGG--LIRPDVVWFGEGLD---AA
VQAVAGADVVIVVGTSSVVYPAAGLPEAALA-GIPVIEVNPQA-PLSAAATAVVREPAALALPGLLQRLPAL-------
>tr|G7CGE4|G7CGE4_MYCTH NAD-dependent deacetylase OS=Mycobacterium thermoresistibile ATCC 19527 GN=KEK_13433 PE=3 SV=1
--------------------------------------------MVTGAGMSAESGVPTFRDVTGLWAKVDPYEISSAEGWRKQPEKVWAWYLWRHYMM-
-SEVKPNDGHRAVAAWEDYA----DVVTQNVDNLHERAG--RVYHVHGSLFEFHCDACRAPFEGNLPE--APDC-FCGG--LIRPNVVWFGENLD---RS
VGSVMNADVVIVVGTSAIVYPAAGLPELALT-GKPVIEVNPER-PLTENATVSLRETAARALPDLLQRLPEL-------
>tr|V5XFU8|V5XFU8_MYCNE NAD-dependent deacetylase OS=Mycobacterium neoaurum VKM Ac-1815D GN=D174_21130 PE=3 SV=1
----------------------------------------MRVTLLSGAGMSAESGVPTFRDVTGLWANVDPYEISSSDGWQRHPERVWAWYLWRHYMM-
-SAVEPNAGHLAVAAWEDYA----HVVTQNVDNLHERAG--RVHHVHGSLFEFRCDRCGTPFTGELPV--VPRC-ACGG--LIRPNVVWFGEGLD---SS
VEAVAKADVVIVVGTSSVVYPAAGLPEAAVA-GIPVIEVNPQP-PLSAACTAVVRETSATALPTLLQRLPQL-------
>tr|I0RPQ2|I0RPQ2_MYCPH NAD-dependent deacetylase OS=Mycobacterium phlei RIVM601174 GN=MPHLEI_15491 PE=3 SV=1
----------------------------------------MQVAVLSGAGISAESGVPTFRDATGLWAKVDPYEISSSEGWRAHPERVWAWYLWRHYMM-
-GAVEPNNGHRAVAAWQDYA----HVVTQNVDNLHERAG--KVYHLHGSLFDFRCDTCDAAYTGELPP--APRC-DCDG--LIRPDVVWFGEALD---AS
VEAISNADLVIVVGTSAIVYPAAGLPELAIA-GIPVIEVNPEP-PLSPSATVSLRETAATALPTLLQRLPAL-------
>tr|A0A0D1J8T1|A0A0D1J8T1_9MYCO NAD-dependent deacetylase OS=Mycobacterium llatzerense GN=TL10_04945 PE=3 SV=1
----------------------------------------MRVTVFSGAGMSADSGVPTFRDATGLWANTDPYEISSSDAWRRHPERVFAWYLWRHHMM-
-GNVSPNDGHRAVAAWQDYT----DIVTQNIDNLHERAG--RVHHLHGSLFQFHCDSCKANFEGTLPE--TPEC-YCGG--LVRPNVVWFGENLD---NS
VAAVSTADLVITVGTSSVVYPAASLPEAAVQ-GIPVIEVNPKP-PFSDQATVSLRETAATALPTLLQRLPEL-------
>tr|A0A0K1R9S5|A0A0K1R9S5_9CORY NAD-dependent deacetylase OS=Corynebacterium riegelii GN=AK829_02175 PE=3 SV=1
------------------------------------LSHAKHIEVFTGAGVSADSGIATYRDATGLWENVDPQAMASIDAWHRDADTMFAWYLWRAHLA-
-QQAQPNAGHLAIANCP-----KTTVTTQNIDNLHERAG--NVVHLHGSLFDFRCTDCDEPYTAEIAL--TPTCPTCGG--LIRPGVVWFGEALA---EA
ERRMRTADALLIVGTSGVVYPAAGLPLMAHA-EIPIIEVTPMR-DLSHLATVVVEDTAANALPKLLG------------
>tr|A0A097ICW4|A0A097ICW4_9CORY NAD-dependent deacetylase OS=Corynebacterium doosanense CAU 212 = DSM 45436 GN=CDOO_00590 PE=3 SV=1
------------------------------------LKGARHIHVFSGAGMSADSGIATYRDATGVWENVDPTAMASIDAWAVRPEEMWAWYLWRASLV-
-RRAEPNAGHRALADLARTR--EVSVTTQNIDDLHERGG--DVTHLHGSLFDFRCSSCGQPWEQEPTL--APRCPSCDG--LIRPGVVWFGEALR---RA
EQHMRSADAVIIVGTSGVVFPAASLPLIAVE-GIPVIEVSPAR-DLTRYVDAYVDGTSAEILPRLVRSLG---------
>tr|A0A077HJ75|A0A077HJ75_9CORY NAD-dependent deacetylase OS=Corynebacterium ureicelerivorans GN=CUREI_07400 PE=3 SV=1
------------------------------------LADASHIEVFTGAGMSADSGIATYRDATGLWENVDPQDMATIDAWHDDPDTMFAWYLWRAHLA-
-QQAEPNAGHIAVANSP-----KTTVTTQNIDNLHERAG--DVVHLHGSLFDFRCSLCDEHFAQPISL--APACPVCGG--RVRPGVVWFGEALA---EA
ERRMRTADALVIVGTSGVVYPAAGLPLIAHA-EIPIIEVTPMR-DLSHLADIVIEGTAAGALPALLG------------
>tr|A0A076NH30|A0A076NH30_9CORY NAD-dependent deacetylase OS=Corynebacterium imitans GN=CIMIT_07630 PE=3 SV=1
------------------------------------LINANHIEVFTGAGMSADSGIATYRDATGVWEQVDPVAMASISAWHDDPDTMYAWYLWRAQLA-
-HRAEPNAGHRAIAAAR-----GVTVTTQNIDNLHERAG--DVVHLHGSLFAFRCTDCDTPYEDPIAL--APHCPVCGG--LVRPGVVWFGEALD---EA
ERRMKTADALLIVGTSGVVYPAAGLPLMAHA-EIPIVEVTPQP-ELSHLASVVVPATAAEALPRILQGRITA-------
>tr|U6ZQP9|U6ZQP9_9PSED Uncharacterized protein OS=Pseudomonas sp. CMAA1215 GN=P308_12670 PE=3 SV=1
------------------------------------LAQARHLVVFSGAGVSAESGIPTFRDATGLWENFDPARLATVQAFRDDPALVWGWYEWRRQKV-
-LAAQPNPAHLAIAELGRRL-PRLTLITQNVDDLHERAG--DVLHLHGSLHSPKCFACNRPFSGALPM--RPRCTGCNG--KLRPGVVWFGEALA---RA
FQAARECDLLLSVGTSGLVQPAAQIPQLALQ-GACVVHINPQP-PGSVPGEYHLVGKAGQVLPQLLQQAFA--------
>tr|Q4KDX3|Q4KDX3_PSEF5 NAD-dependent deacetylase OS=Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477) GN=PFL_2453 PE=3 SV=1
------------------------------------LAQARHVVVFSGAGVSAESGIPTFRDATGLWEHFDPARLATVQAFREDPALVWGWYEWRRQKV-
-LQAQPNPAHLALAELARRV-PRLTLITQNVDDLHERAG--SVLHLHGSLHTPKCFACSRPFKGQLPL--SPRCTGCNG--KIRPGVVWFGEPLA---AA
FNAAEECDLLLSVGTSGLVQPAARIPQLALQ-GACVVHINPQP-ACTGAEEYSLEGKAGQLLPELLRQAFA--------
>tr|A9AWT4|A9AWT4_HERA2 Silent information regulator protein Sir2 OS=Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785) GN=Haur_0687 PE=4 SV=1
------------------------------------LRQTQSLVVLTGSGISAPSGIPTYRSADARWTAYDPDKVATFAGFERDPVGVFQVYQAMKRQC-
-EAAQPNAGHYALAQLEQL--TQFKLFTQNIDSLHQRAG--QVYEVHGSLARTICS-GNLVETWNA-----PICPACGA--PLRPDIVWFGELLG---AA
KAAFDSSDVALVIGTSAIVEPIASLPHRALR-KKTVIEINPDI-LRGI-ATFSLAGSADELLPQLIKEVWKL-------
>tr|A0A072NCB6|A0A072NCB6_9DEIO NAD-dependent protein deacylase OS=Deinococcus sp. RL GN=RDMS_04375 PE=3 SV=1
------------------------------------LRAARRVAVLTGAGVSAESGIPTFRDA-GHWARFRPEDLASPDAYRRDPDTVWAWYAGRYRDV-
-SRAQPNGAHHLLARLER---EGFFLATQNVDGLHVRAG--RLVELHGNLGTARCEVCGA-------VA-FPTCPVCSS--RMRPNVVWFGEFLG---AA
AQAFGEADVALVIGTSGQVYPAAGLALETRR-GGTVIEVNPDE-DLTPHMSCSVRDVASRGLAALMAER----------
>tr|K9ZZS5|K9ZZS5_DEIPD NAD-dependent protein deacetylase, SIR2 family OS=Deinococcus peraridilitoris (strain DSM 19664 / LMG 22246 / CIP 109416 / KR-2
------------------------------------LGRASRVAVLTGAGISAESGIPTFRDA-GLWARFTPEELASPAAYARDPLFVWNWYAERYRAC-
-MQAEPNAAHRALVELER---A-FLLVTQNVDGLHGRAG--RLIELHGNLNTARCERCALIQSLPA----FAHCQRCGA--RARPNVVWFGEMLD---RS
WQAFESAEVALVIGTSSVVEPAASLGRLAKS-GAYLIELGPDA-PLTPYTDTSLRLGAVAGMQALMEQDT---------
>tr|C1CZ00|C1CZ00_DEIDV Putative NAD-dependent deacetylase (Regulatory protein SIR2-like protein) OS=Deinococcus deserti (strain VCD115 / DSM 17065 / L
------------------------------------LRDARRVAVLTGAGVSAESGIPTFRDA-GHWARFRPEDLASPDAYRQDPDTVWEWYAGRYRDV-
-LRAEPNGAHYLLAQLEG---NGFLLATQNVDGLHARAG--RLVELHGNLLSARDEITGE-------VF-LPVSP-NGH--RMRPNIVWFGEFLD---TA
SEAFASADVALVVGTSGVVYPAAGLALETLR-GGVVIEINPEE-ELTPLLSFSVRDVASRGLAALLGQAAS--------
>tr|A0A016QU28|A0A016QU28_9DEIO Silent information regulator protein Sir2 OS=Deinococcus phoenicis GN=DEIPH_ctg004orf0057 PE=3 SV=1
------------------------------------LGNARRVAVLTGAGVSAESGIPTFRDA-GHWARFRPEDLASPEAYRRDPETVWQWYAGRYADV-
-TRARPNGAHRLLAGLER---DGFFLATQNVDGLHTRAG--HLAELHGNLTTARCEGCGT-------VT-FPVCPGCGH--RMRPNIVWFGEFLE---AA
TRAFQDADVALIVGTSGMVYPAAGLALETRR-GGVVIEMNPEE-ELTPYMDFSLRDVASKGLAALVGEAPA--------
>tr|A0A0A7KGU2|A0A0A7KGU2_9DEIO NAD-dependent protein deacylase OS=Deinococcus swuensis GN=QR90_09770 PE=3 SV=1
------------------------------------LAAARRVAVLTGAGVSAESGIPTFRDA-GLWARFRPEDLASPDAYFRDPALVWEWYAGRYRDV-
-MAATPNAGHDLLTRLER---DGFFLATQNVDGLHARAG--RLVELHGNLTTARCEVCGQ-------VD-FPVCAVCGG--RMRPNIVWFGEFLA---AA
ANAFAAADVALIIGTSGVVYPAAGLAFETLR-GGTVIEINPDQ-ELTPRLSFSLRETASAGLAALMDAG----------
>tr|A0A0A7GGT7|A0A0A7GGT7_9EURY NAD-dependent protein deacetylase of SIR2 family OS=Geoglobus acetivorans GN=GACE_2039 PE=3 SV=1
------------------------------------KSCNGELVALTGAGISADSGIPTFRGK-GLWNKYRPEELATPEAFRKDPVLVWKWYAWRMNLV-
-FNAEPNDAHIALALLER---L-KAIVTQNVDNLHERAG--NVIHLHGRIDEVRCTGCGRVGRLEKA----PPLCGCGA--LMRPNVVWFGEPLE---LA
VELCSQNSV-IVIGTSAVVYPAAQLPYYAKK-GKTVIEVNPEI-PLSDLADLSIRQRAGDAFRQIRAILEAG-------
>tr|D3RWK7|D3RWK7_FERPA Silent information regulator protein Sir2 OS=Ferroglobus placidus (strain DSM 10642 / AEDII12DO) GN=Ferp_0700 PE=3 SV=1
--------------------------------------KDNEVVVLTGAGISADSGIPTFRGK-GLWNKYKPEELATPEAFRRNPKLVWEWYMWRMEKV-
-FNAKPNKAHLALAKLEE---V-KAVITQNVDNLHERAG--NVIHLHGRIDEARCEVCGRIVRFEKP----PY---CCS--MMRPNVVWFGEALD---KS
IELVEKYDV-LVVGTSGVVQPAASLPIIAKK-GNKVAEVNVEE-AITPIVDIFVRGRASEVFEEILRIIEQT-------
>tr|A0A0F7IEL5|A0A0F7IEL5_9EURY NAD-dependent protein deacetylase OS=Geoglobus ahangari GN=GAH_00653 PE=3 SV=1
------------------------------------RRCSGNLVALTGAGISADSGIPTFRGK-GLWNKYRPEELATPQAFAKNPRLVWEWYAWRMEKV-
-FSARPNPAHLALAIMER---L-KAVITQNVDNLHERAG--NVIHLHGRIDEMRCLGCDRIVRVAKP----PPVCECGE--MMRPNVVWFGEALR---LA
MSLCEENSV-LVIGTSAVVYPAAYLPHHAKR-GNMVIEINPDV-PVTDIADLSVRERAGKFFEPLLPILEEE-------
>tr|A0A0R3FQK3|A0A0R3FQK3_9MYCO NAD-dependent deacetylase OS=Mycobacterium sp. H002 GN=AOT84_19620 PE=4 SV=1
------------------------------------AAKARTVAVLTGAGMSAESGLPTFRDATGLWSKYDPMTLATPEAWNEDPGLVWAWYQNRRIQL-
-MAVQPNDGHRALAQWGACR--DVKIVTQNVDDLHERAG--EVTHVHGSLLKSHCDTCRTGFDVS-----RPDCG-CGG--KVRPSIVWFGEMLV---HA
VAHAQNCELMLLVGTSGIVYPAAGLPQLALS-GATVVEINPQE-DLSDRADLVWRATAATALPALVEALALS-------
>tr|B1MER1|B1MER1_MYCA9 NAD-dependent deacetylase (Regulatory protein Sir2 homolog) OS=Mycobacterium abscessus (strain ATCC 19977 / DSM 44196 / CIP 104
------------------------------------ASKARSVTVLTGAGMSAESGLPTFRDATGLWSKYDPMTLATPESWQEDPGLVWAWYQNRRIQL-
-LAVQPNDGHRALAQWGSHR--DIRIVTQNVDDLHERAG--NVTHVHGSLLKSHCDTCRSDFEAT-----RPECG-CGG--KVRPSIVWFGEMLV---HA
VAHSQNCDLMLLIGTSGIVYPAAGLPQLALS-GATVVEINPQE-DLSDRADLVWRSTAATALPALLQALAPF-------
>tr|A0A0Q5QSU6|A0A0Q5QSU6_9ACTN NAD-dependent deacylase OS=Williamsia sp. Leaf354 GN=ASG12_07520 PE=4 SV=1
------------------------------------IAPARTVTVLTGAGMSAESGVPTFRDVTGLWARYDPMTLATPEAWDDDPALVWAWYQRRRAMV-
-TAVEPNDGHRALAGWARSA--DIRVMTQNVDDLHERAG--EVVHVHGSLFACRCDTCGRAYEPE-----RPECD-CGG--LVRPGVVWFGEALN---EA
TARAEAADVFVLVGTSGVVYPAAGLPHIARA-GATIIEINPHE-DLSDACDITIRSTAAVAIPAIVDACTS--------
>tr|F6EQ07|F6EQ07_AMYSD NAD-dependent deacetylase OS=Amycolicicoccus subflavus (strain DSM 45089 / DQS3-9A1) GN=AS9A_3387 PE=3 SV=1
------------------------------------VKKADRITVLSGAGMSAESGLPTFRDATGLWERFDAAALATPEAWNRDPEFVWSWYMWRHHLV-
-RATAPHAGHLAVAQWEHSA--DVTIVTQNVDDLHERAG--HVHHLHGSLFHFRCAQCSFAYSDEV----PPRCQRCGG--LIRPGVVWFGEMLE---AG
VQAVDSCDVLVVVGTSGLVYPAAGLPQIAHE-GIPTIEINPDE-PLSRECTVSLRMSAATALPILARSR----------
>tr|E5XRZ1|E5XRZ1_9ACTN Uncharacterized protein OS=Segniliparus rugosus ATCC BAA-974 GN=HMPREF9336_02263 PE=3 SV=1
------------------------------------RDFVRRVVVLSGAGMSAESGMPTFREATGLWEQFDPTELASPQAWRADPEFVWAWYLWRHELA-
-RRALPNAGHLAIAEWESRA--EVVVITQNVDDLHERAG--DVVHVHGSLFAFRCADCASPYDGQ---V-RPRCPRCGS--AVRPGVVWFGEALA---RA
VRAVGEAALLVVVGTSGVVYPAAGLPALAKA-GARVVEVNPEP-ALTGEVDEFVRAKAGAALPGLLDRLLP--------
>tr|E6JCE8|E6JCE8_9ACTN Silent information regulator protein Sir2 OS=Dietzia cinnamea P4 GN=ES5_14578 PE=3 SV=1
------------------------------------LAGDGSLVVLSGAGMSAESDVPTFRDATGLWERYDPAALATSEAWARDRDTVWAWYRWRENLI-
-SHAQPNAGHLAVARAAERR--DVIVVTQNVDDLHERAG--VVHHVHGSLFSHRCDTCGTPMDVG-----RPHCIACGG--RARPGIVWFGEMLG---ES
VAAIDRAAAVLVVGTSGLVHPAASLPDLAAE-GIPVVEVNPGP-GLAPAVTVHVRATAGEAVPEILS------------
>tr|M6CG73|M6CG73_LEPME Transcriptional regulator, Sir2 family OS=Leptospira meyeri serovar Semaranga str. Veldrot Semarang 173 GN=LEP1GSC196_0923 PE=3
------------------------------------IRSATNVLFLTGAGISSESGIPTFRGD-GYWKKFKAEELATPEAFAAHPEVVWDWYDYRRNVC-
-FEAKPNDGHLTIARWQS-Y-KTVNLITQNVDGLHPRAG--NLLEIHGNIFRARCT-CGDKFALGE----QKYCPNCES--LLRPDIVWFGESYR---KA
WEQSKQTQVVFVIGTSANVSVPANLALTAIR-GALGIEINPES-TLTPSMQVHFGGKSGETLPEIFKEVFPD-------
>tr|N1VY77|N1VY77_9LEPT Transcriptional regulator, Sir2 family OS=Leptospira terpstrae serovar Hualin str. LT 11-33 = ATCC 700639 GN=LEP1GSC203_2583 PE
------------------------------------IRSARNLLFLTGAGISSESGIPTFRGE-GYWKTYKAEELATPEAFARHPEVVWEWYDWRRGIC-
-RETKPNDGHLTIAKWQF-K-ESVNLITQNVDGLHPRAG--HLLEIHGNIFRARCT-CHAKFDLEE----QKYCIACES--LLRPDIVWFGEGYR---KA
WELSKVAHVVFVIGTSANVSVPSNLALTAVR-GALGIEINPET-SLTPSLQLHLGGKSGEILPEIFKEVFPD-------
>tr|R8ZV10|R8ZV10_9LEPT Transcriptional regulator, Sir2 family OS=Leptospira yanagawae serovar Saopaulo str. Sao Paulo = ATCC 700523 GN=LEP1GSC202_1838
------------------------------------IRNADKIVFLTGAGISNESGIPTFRGE-GLWKNFRAEDLATPSAFQKDPNLVWEWYDWRREIC-
-QKAKPNPGHLTIAKWQK-K-KSVSLITQNVDGLHPRAG--SLIELHGNIFRARCT-CSEKFHLVN----HKYCKHCES--LLRPDIVWFGEEYT---KS
WELCKQSQVVFVVGTSANVSVPANLAHTAIR-GAIGIEINPDE-NLTPSMKHHFDGKSGEVLPQIWKEVFPN-------
>tr|B0SL46|B0SL46_LEPBP Putative NAD-dependent deacetylase OS=Leptospira biflexa serovar Patoc (strain Patoc 1 / ATCC 23582 / Paris) GN=LEPBI_I0721 PE=
------------------------------------IQNAPSIVFLTGAGISSESGIPTFRGE-GLWKNFRAEDLATPEAFQKNPKLVWEWYDWRREIC-
-QKAKPNLGHLIIAKWQK-K-SSVHLITQNVDGLHPRAG--TLIELHGNIFRVRCT-CTSIFHLEK----HKFCKECDS--LLRPDIVWFGEEYN---KS
WELCKQSQVVILIGTSANVSVPTNLAQTAIR-GAIGIEINPEE-NLTPSMKHHFDGKSGEVLPQIWKEVFPD-------
>tr|R9A5E9|R9A5E9_9LEPT Transcriptional regulator, Sir2 family OS=Leptospira wolbachii serovar Codice str. CDC GN=LEP1GSC195_2602 PE=3 SV=1
------------------------------------IRSARNILFLTGAGVSSESGIPTFRGE-GYWKTYKAEELATPEAFLRHPDVVWEWYDWRRGIC-
-REAKPNEGHLTIAKWQS-F-PSVNLITQNVDGLHPKAG--NLLEIHGNIFRARCT-CQAKYHLEE----QKFCTTCES--LLRPDIVWFGEGYR---KA
WELSKVAHVVFVIGTSANVSVPANLALTAIR-GALGIEINPET-SLTPSIQLHFGGKSGEILPEIFNDVFPD-------
>tr|A0A0Q8R325|A0A0Q8R325_9BURK NAD-dependent deacylase OS=Noviherbaspirillum sp. Root189 GN=ASE07_16065 PE=4 SV=1
------------------------------------LRSARHIAVFTGAGVSAESGIPTFRDA-GLWAKFRAEDLATPEAFRRDPVTVWNWYAWRRELM-
-ADAGPNPAHLAIAQMQQ---PELTVITQNVDGLHAKAG--NVIELHGNIWNDFCADCRQ-------QA-NPRCTHCGG--MLRPGVVWFGEALD---RA
SDVLEVADVFFCIGTSSLVEPAASLPRYARS-GRTVVQINPEA-SHDEIAQYVLRGKAGEVLPQLVQAAWPQ-------
>tr|L0DRG0|L0DRG0_SINAD NAD-dependent protein deacetylase, SIR2 family OS=Singulisphaera acidiphila (strain ATCC BAA-1392 / DSM 18658 / VKM B-2454 / MO
------------------------------------LAKAGSVAVLTGAGISAESGIPTFRGL-GLWNGRDPMSLATPQAFAANPALVWEFYNWRRELV-
-TRAEPNPGHRALTELAG---TCFTLVTQNVDRLHQRAG--DVLELHGNLFEVRCTGCGQ-------TF-LPHCEVCGQ--LLRPGVVWFGETLA---AA
EAAVRQARLLLVVGTSAVVYPAAGLVATAQS-GGAVIEINLEP-PISDEVDLALHGKAAAILPLLTDLL----------
>tr|A0A0C4WS14|A0A0C4WS14_9GAMM NAD-dependent protein deacetylase of SIR2 family OS=Azotobacter chroococcum NCIMB 8003 GN=Achr_16140 PE=3 SV=1
------------------------------------LRDTSRVVFFTGAGVSAESGIPTFRDATGLWARYRPEELASPEGFRADPRTVWEWYAWRREKC-
-LAAEPNPAHLAIAALERRL-PGVTLITQNVDGLHQRAG--APLELHGNLHRLKCFRCEADGGDWP----TLPHCACGG--LLRPAVVWFGENLD---RA
SEAGLQAGLFFSVGTSSLVYPAAELPFSAKR-GAFVVEINPQP-PLSRHADLCLHGPAGSVLPELLAALEG--------
>tr|A0A0C2BPI6|A0A0C2BPI6_9BURK Uncharacterized protein OS=Herbaspirillum sp. TSA66 GN=TSA66_16005 PE=3 SV=1
------------------------------------LRGARHIAVFTGAGVSAESGIPTFRDA-GLWANFRAEDLATPEAFRRDPATVWKWYEWRRDLM-
-RNLQPNAAHLAIAALER---PRVTMITQNVDGLHHRAG--DVIELHGNIWNNFCFQCRK-------PA-SPRCAHCDG--MLRPGVVWFGESLP---RA
ADLSEHADVFFCIGTSSLVEPAASLPRYAQS-GRVVIQINPEA-MHDGFARHVLRGKAGDIVPQLLCAAWPG-------
>tr|A0A0F9Q3L8|A0A0F9Q3L8_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_1062760 PE=3 SV=1
------------------------------------LQDASRVAVLTGAGISAESGIPTFRGE-GLWKKYRPEELATPTAFSRDPKLVWEWYDWRRVIF-
-AQKEPNPGHKVIARWEG---T-VSLITQNIDGLHQKAG--NIWELHGNIWKVRCTEEGTITENYDTP--KPLCPNCGA--LLRPHVVWFGESLT---KS
IQLSSECDVMFVIGTSAVVQPAASLPFEASE-GAKIVEINPDP-PFSLYADFSIRGKSGEILPLIDEELKKT-------
>tr|X1SJ74|X1SJ74_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=S12H4_02686 PE=3 SV=1
------------------------------------IKKGKRCVVLTGSGVSAESGIPTFRGD-GLWKEYRPEELATPDAFMRNPQLVWEWYNWRRGII-
-AKAKPNAAHYVISDMEK---D-FMLITQNIDGLHRKAG--DILELHGNIWENKCFNCGKRYGEIM----SQKC-ECGG--YLRPDVVWFGESLE---MA
FLKAREAELCFVIGTSGVVQPAASLPYVSKE-GAYIVEINLER-PISSIADEFISGKAGEALVKMRESFLQG-------
>tr|B7R770|B7R770_9THEO Sir2 family NAD-dependent protein deacetylase OS=Caldanaerobacter subterraneus subsp. pacificus DSM 12653 GN=CDSM653_01487 PE=3
------------------------------------LPQSNLTVVLTGAGISKESGIPTFRGE-GLWKKYNPEELATPWAFQRNPALVWEWYDYRRRII-
-SKAKPNKCHLLIAEFEE---N-VRVITQNVDGLHEAAG--NVIELHGNIWKVKCTKCDFRGINR-----SPECPKCGS--IVRPDVVWFGEPLD---EA
MELSQRADLFIVIGTSLMVQPAASLPFLALE-GAFVVEVSPEE-PLSRKAHLFFQMGAVEFAMKFEEKEG---------
>tr|D8PE10|D8PE10_9BACT NAD-dependent deacetylase OS=Nitrospira defluvii GN=npdA PE=3 SV=1
------------------------------------LASARSVTVLTGAGISADSGVPTFRGA-GLWRTFRAEDLATPEAFARDPRLVWEWYNWRRELI-
-ATKRPNPAHEAVAQMEQ---R-FWLITQNVDGLHRDAG--KLSEIHGNIWMVRCTQCRRVTENRDVP--APRCSHCSG--LLRPHIVWFGESLQ---AS
EAALQSSDLCLIVGTSGLVYPAAGFGSIAKQ-GAFVVEINLDA-AQSGIVDAALQGRAKDIVPLLLQA-----------
>tr|A0A0K2GD46|A0A0K2GD46_9BACT NAD-dependent protein deacylase OS=Nitrospira moscoviensis GN=cobB PE=3 SV=1
------------------------------------IAAAQSITVLTGAGISADSGVPTFRGA-GLWRNFRAEDLATPEAFERDPRLIWEWYNWRRELI-
-ATKRPNPAHEAVAELER---R-FWLITQNVDGLHRAAG--KLSEIHGNIWTVRCTGCGTIADNHDVP--APFC-QCGS--LLRPHIVWFGESLD---QC
AAALRRCDVLLVIGTSGVVYPAAGFASVAKE-GAFVAEINLDP-PQSSLVDLSLQGRAKEIVPLLLEPV----------
>tr|F2ND26|F2ND26_DESAR NAD-dependent deacetylase OS=Desulfobacca acetoxidans (strain ATCC 700848 / DSM 11109 / ASRB2) GN=Desac_1760 PE=3 SV=1
------------------------------------LFGSQHAVALTGAGISAESGVPTFRGQ-GLWQHYRAVDLATPEAFGRDPRLVWEFYQWRRRLL-
-GPVRPNPAHTTLAELER---N-FTVITQNIDGLHQMAG--RIIELHGNIWYLRCTGCGLILEDRRTD--PPKCDACGR--LLRPHVVWFGEMLV---QA
YAALHTCEMLLVIGTSGLVQPAASMGAVAKH-GALVVEINLEP-PQSDLYDFSWQGKAGELLPQLLQGE----------
>tr|A0A073IS34|A0A073IS34_9BACT NAD-dependent deacetylase OS=Synergistes jonesii GN=EH55_04655 PE=4 SV=1
------------------------------------LVRAGDVVIFSGAGLSTESGLQDFRSKNGIWAHADPARLASVGALECNYDEFLEFYKARLYVP-
-DEVKPNIGHKIVAKWEK---CVKGVITQNIDRLHQRAG-VNVWELHGSLEPIKCHSCGKPGSN-------TPCKYCGG--HLRPSVVLFGEMLRALEAA
DELSGSCKTFIVLGSSLVVSPANYFPRQAKM-GAKLAIVNLEE-PLDGIADITVHEGIGAFLSDTEKYMRQQ-------
>tr|A0LP75|A0LP75_SYNFM Silent information regulator protein Sir2 OS=Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) GN=Sfum_3557 PE=3 SV=1
------------------------------------LSGAENVVVLTGAGISAESGVPTFRGE-GLWRTYRATDLATPEAFENDPKLVWEFYGWRRQLL-
-APLDPNPGHYALAELER---R-FTLITQNIDGLHQKAG--NILELHGNLWWVRCTRCGSLTEDRTVP--PPRCGSCRG--LLRPHVVWFGEMLK---QA
YEAIRDCGVMLVVGTSGTVQPAASMGVIARK-GATVAEVNLDP-PYSGAYDISISGKAGEILPRLL-------------
>tr|A0A0Q7B1V7|A0A0Q7B1V7_9PSED NAD-dependent deacylase OS=Pseudomonas sp. Root401 GN=ASC85_02175 PE=4 SV=1
------------------------------------LRAARHLAIFTGAGISAQSGISTFRDPTGLWARYDPKKLATPAAFAKDPALVWAWYSWRRTLV-
-NEAQPNDAHRAVARLTQNL-PRVTVITQNVDDLLERAG--EVIHLHGELASARCFQCNRSYLGALPM--NPRCPHCNG--LIRPNVVWFGEGMQ---QA
FSAARDCDVMLSIGTSGNVYPAARIPTLATE-GAWLVHINIEL---GAASDKTLVGDATHWLPRLVDALDWS-------
>tr|V6GKU0|V6GKU0_9LEPT Transcriptional regulator, Sir2 family OS=Leptospira noguchii str. Cascata GN=LEP1GSC073_2315 PE=3 SV=1
------------------------------------KGKFQKISAISGAGISAESGIPTFRGN-GLWKNFRAEDLATPEAFSKNPKLVWEWYLWRRNII-
-ESKRPNPGHEALVILEKS--PDFFLITQNVDGLHSQAG--KLTEIHGNIFINRCISCGQESKEKI----TPQCKNCNS--FLRPGVVWFGESYR---AS
ILRMEGTDLLLILGTSGSVSMPVYLAQIAKD-GAFLVEINPER-SFSSSVDLFLQGKTGEVLPLLVREILDN-------
>tr|V6I4E8|V6I4E8_9LEPT Transcriptional regulator, Sir2 family OS=Leptospira kmetyi serovar Malaysia str. Bejo-Iso9 GN=LEP1GSC052_1123 PE=3 SV=1
------------------------------------KQKLKKITAIVGAGVSAESGIPTFRGA-GLWKNFRAEDLATPEAFSKNPKLVWEWYLWRRNII-
-ESKRPNAGHEALVLLEKS--PDFYLITQNVDGLHDSAG--KLVEIHGNIFVNRCVSCGREDKKRI----NPKCDYCAS--FLRPGVVWFGESYQ---AS
IQRMENTDLLLILGTSGSVSMPVYLAQIAKR-GALLLEINPER-SFSSSVDLFLQGKTGEILPELVQEILNV-------
>tr|A0A0G3BSR8|A0A0G3BSR8_9BURK NAD-dependent protein deacylase OS=[Polyangium] brachysporum GN=npdA PE=3 SV=1
------------------------------------IAQARRLCVSTGAGMSAESGVPTFRDA-GMWARFDPQQLATEAGYRADPQLVWDWYASRREGV-
-AQAQPNGGHVALAEWQR---GRMTLITQNVDDLHQRAG--DVVCLHGGLFVDRWLDPCPRWKGG-QPC-PPHCETCGN--RVRPGVVWFGEALQ---AA
EDAANDCDVMLVVGTSGAVYPAAGLPLLARQ-GAKVVVLNPQP-ELDDTAHLVLRDTAAHGLPLLLT------------
>tr|I4MP78|I4MP78_9BURK Silent information regulator protein sir2 OS=Hydrogenophaga sp. PBC GN=Q5W_2209 PE=3 SV=1
------------------------------------VRSARAIAVLSGAGMSAESGVPTFRDA-GLWARFDPQQLATEAAFRRQPQLVWDWYAERRAAL-
-ERVQVNAGHVAIADFQR---GRLTVITQNVDGLHQRAG--GVLALHGNIAQDRWLDAPR-------AC-DPRCGVCGN--LRRPAVVWFGEMLA---AA
QAAAEACDLMLVVGTSGEVYPAAGLASVAGQ-GARVLIVNPDA-ALDGVATRCLRATAAVALPALLDGA----------
>tr|S6K0H8|S6K0H8_PSEST Cobalamin biosynthetic protein OS=Pseudomonas stutzeri B1SMN1 GN=B382_04705 PE=3 SV=1
------------------------------------LRSARHVVVFTGAGVSAESGIPTFRDATGLWERFDPGELATADAFRRDPALVWGWYEWRRMKV-
-LQARPNPAHMAIAELAGHV-PQLTLITQNVDDLHERAG--EVIHLHGSLHRPRCFACAREPAEPLPA--RPRCRHCGG--RLRPGVVWFGESLD---AA
FAAARACDLLLSVGTSGVVYPAAEVPHLARA-GATLVHVNPQG-APQSAHEHLLALPAGQALPQLVREAFGG-------
>tr|A0A078LMQ7|A0A078LMQ7_9PSED Cobalamin biosynthetic protein OS=Pseudomonas sp. 20_BN GN=BN1079_01130 PE=3 SV=1
------------------------------------LKAADRIVVLTGAGVSAESGVPTFRDPTGLWRRFDPMELASAQAFSRNPAMVWGWYEWRRMKV-
-MQAQPNPAHRALARLAERK-PEMILITQNVDDLHERAG--RVIHLHGSLQQPRCFACARPATALAT---APRCQHCGG--LLRPGVVWFGESLS---SA
FKAAQEAELLMVVGTSGVVYPAAELPAIARR-GAKILHINPQL-L--EAGDWGIEGLAGEVLPQLIG------------
>tr|A0A0D9B0K4|A0A0D9B0K4_PSEFL NAD-dependent deacetylase OS=Pseudomonas fluorescens GN=UG46_10170 PE=3 SV=1
------------------------------------LRDASHVVVFTGAGVSAESGIPTFRDATGLWERFDPAVLATADAFRNDPALVWGWYEWRRSKV-
-LAAKPNPAHLAVAELARLV-TRLTVITQNVDDLHERAG--GVIHLHGCLHSPRCFACARPYKGTTDQ--RPRCRHCNG--KVRPGVVWFGESLQ---EA
LAAVRDCDLLLSVGTSGLVQPAAEIPRIARE-GAVVVHVNLQR-SVQGEREFSLVGKAAEILPRLLAQANE--------
>tr|A0A0K1QQR9|A0A0K1QQR9_PSEFL NAD-dependent deacetylase OS=Pseudomonas fluorescens NCIMB 11764 GN=B723_16945 PE=3 SV=1
------------------------------------LRSARHVVVFSGAGISAESGIPTFRDATGLWENFAPAALATAQAFRNDPALVWGWYEWRRAKV-
-LGAQPNAAHRAIAALARRV-PMLTVVTQNVDDLLERAG--DVLHLHGSLSSPRCFACARPYTFSADP--RPRCRHCNG--KVRPGVVWFGESLD---KA
VSAAKDCDVLLSIGTSGLVQPAAEIPRIALQ-GAQVLHINLQP-PVKGDREFSLAGRAAEVLPRLVEEVFAE-------
>tr|U3H7U4|U3H7U4_PSEAC Uncharacterized protein OS=Pseudomonas alcaligenes OT 69 GN=L682_20330 PE=3 SV=1
------------------------------------LAKARHLVVFTGAGISAESGIPTFRDRTGLWERYEASELASAEGFRRDPALVWGWYEWRRTLV-
-HRAQPNAGHLAIARLAALV-PKLTLITQNVDDLHERAG--EALHLHGRLDALRCFACTRPAL-EIPK--RPRCTRCNG--KLRPGVVWFGEQLD---AA
FTAAEECDLLLSIGTSGVVEPAARIPRLALN-GATVLHLNTQP-AVQGEREFALAGPAGELLPALLHQAFGA-------
>tr|A0A031M8C0|A0A031M8C0_9PSED NAD-dependent deacetylase OS=Pseudomonas bauzanensis GN=CF98_08545 PE=3 SV=1
------------------------------------IRKSRRMVISTGAGISAESGIATFRDPDGLWSQYDPELLSTPEAFRRDPSLVWGWYETMRGQM-
-RNASPNPAHHAVTELTVIV-PEVALITQNIDDLHERAG--DVIHLHGRVFDSRCFACARPHYRRD----PPRCGHCNG--RIRPGVVWFGEQLR---RA
FDAAKRCDCLISIGTSGEVNPAATLPDIALD-GASVIHVNIDP-CQHRPNEYLLEGRASEIMSTVLAEAFPS-------
>tr|A0A0B3BP03|A0A0B3BP03_9PSED NAD-dependent deacetylase OS=Pseudomonas tuomuerensis GN=PT85_12520 PE=3 SV=1
------------------------------------LRKARHLVVFTGAGVSAESGIPTFRDASGLWERFDPAELATPSAFRRDPALVWGWYEWRRMKV-
-LQAQPNPAHRAIAALAERV-EKLTLITQNVDDLHERAG--DVIHLHGSLHAPRCFACGRPHA-ISEV--CPRCQRCNG--KVRPGVVWFGEALA---AA
FKAAGECDVLLSIGTSGVVQPAASIPQLALQ-GATVAHINPQP-GQGGAREFSLAGAAGVVLPELLGQLDAR-------
>tr|A0A0C2S8D3|A0A0C2S8D3_PSEST NAD-dependent deacetylase OS=Pseudomonas stutzeri GN=QX25_05780 PE=3 SV=1
------------------------------------LRNARHLVVFTGAGVSAESGIPTFRDSTGLWQRFDAATLATPEAYEQDPALVWGWYEWRRMQV-
-LKAQPNAAHRAIAALVQQV-PRLTLVTQNVDDLHERAG--DVIHLHGSLHHPRCVVCSRQPSKPLPP--RPRCEYCDG--KLRPGVVWFGESMG---DA
FAAARHCDVLISVGTSGVVYPAAEMPERAWR-GATVIHVNPQP-VTHSEREYALGGSAGEVLPQLFEEAFGR-------
>tr|H7EU41|H7EU41_PSEST Cobalamin biosynthetic protein OS=Pseudomonas stutzeri ATCC 14405 = CCUG 16156 GN=PstZobell_07492 PE=3 SV=1
------------------------------------LRSARHVVVFTGAGVSAESGIPTFRDATGLWERFDPGELATPEAFRRDPALVWGWYEWRRMRV-
-LQSQPNPAHLAIADLARHV-PQLTLITQNVDDLHERAG--DVIHLHGSLHRPRCFACAREPAEPLPA--RPRCSHCGG--RLRPGVVWFGESLA---AA
FKAAGECDLLLSVGTSGVVYPAAEVPHRARD-GATVVHINPQG-ATAGNREHLIAMSAGQALPKLLREAFGG-------
>tr|A0A023WSJ3|A0A023WSJ3_PSEST NAD-dependent deacetylase OS=Pseudomonas stutzeri GN=UIB01_12220 PE=3 SV=1
------------------------------------LRSARHVVVFTGAGVSAESGIPTFRDASGLWERFDPSELATPEAFRRDPALVWGWYEWRRMQV-
-LKARPNPAHVAIAELAHHV-PRLTLITQNVDDLHERAG--GVIHLHGNLHRPRCFACAREPAEPLPV--RPRCSHCGG--QLRPGVVWFGESLD---AA
FQAAGECDLLLSVGTSGVVYPAAEVPHRARD-GATVVHVNPQG-PTAGNREYLIALPAGEALPELLRAASGA-------
>tr|W9TSH7|W9TSH7_9PSED Cobalamin biosynthetic protein OS=Pseudomonas sp. BAY1663 GN=BAY1663_01788 PE=3 SV=1
------------------------------------LRSARHLVVFTGAGVSAESGIPTFRDASGLWQRFDPAALATPQAFRRDPALVWGWYEWRRMKV-
-LQAQPNPAHRAIAELARHV-PEFTLITQNVDDLHERAG--AAIHLHGSLHQPRCFACARSPAAPLAP--RPRCAHCGG--RLRPGVVWFGESLA---AA
FDAARRCDLLISVGTSGVVYPAAEVPRVALD-GAVVLHVNPQA-AQPGEREFVLRGPAGEELPELLRQAFGA-------
>tr|A0A069IE30|A0A069IE30_9BURK NAD-dependent deacetylase OS=Cupriavidus sp. SK-3 GN=CF70_034260 PE=3 SV=1
------------------------------------LRGARHLVILTGAGVSAESGVPTFRGPGGLWERFEPAQLANADAFRRDPELVWGWYEWRRMLV-
-SKAQPNPAHLAIARMAAKV-PRLTLVTQNVDNLHERAG--NLLHLHGSLHHPICFACRRPHALPPGI--RPLCGHCGA--RIRPGVVWFGESLD---AA
AAASDECDMLISVGTSALVHPAASLPLRVAE-RRPVVQVNPER-ALSAVADYDLTGPAGLLMPALYEAAWGP-------
>tr|C7RQR7|C7RQR7_ACCPU Silent information regulator protein Sir2 OS=Accumulibacter phosphatis (strain UW-1) GN=CAP2UW1_1081 PE=4 SV=1
------------------------------------LRRAREVVVFSGAGLSADSGIPTFRDG-GLWNNVDPDEVASIEGFLRKPRVVWDWLLQLKNLV-
-DDRHPNAGHEAIARLEDLC-KRLTIITQNIDGYHTQAG--QVLEVHGTIHRVRCH-CGFAAVWEQ----AFSCPNCGG--PVRPDLVLFGEMLE---AA
GIRSLNADLFFCVGTSFTVQPAARLPVWAKG-GATVVEVNPHP-PLSDAADYSIRAGASQFFGALCARLQEN-------
>tr|A0A080M2B0|A0A080M2B0_9PROT NAD-dependent protein deacylase OS=Candidatus Accumulibacter sp. SK-02 GN=cobB_3 PE=4 SV=1
------------------------------------LREASEVVVFSGAGLSADSGIPTFRDG-GLWNNVDPDEVASIEGFLRNPQRAWSWLLQLRNLV-
-DERHPNAGHHAIARLDEIC-QQFTVITQNIDGYHVRAG--HVLEVHGTIHRVRCH-CGFVASWNR----AYACPACGA--PVRPDLVMFGETLS---AA
ERSSLKADVFFCVGTSFTVQPAARLPLWAKS-GAVVVEVNPHP-PLSDVADYSIRCGSSQFFSALCATLEAV-------
>tr|A0A011MPE8|A0A011MPE8_9PROT NAD-dependent protein deacylase OS=Candidatus Accumulibacter sp. SK-12 GN=cobB_4 PE=4 SV=1
------------------------------------VQAARRVVVFSGAGLSADSGIPTFRDG-GLWNNVDPDEVASIQGFLRNPRRVWSWLLELKALV-
-DDRRPNPGHLAIARLEELC-SRFTVITQNIDGYHALAG--DVLEVHGTIHRVRCH-CGYASSWDQ----AFACPDCGA--PVRPDLVMFGEMLE---AA
QACSLNADVFFCVGTSFTVQPAAHLPVWAKY-GATVIEVNPHP-SLSEAADYSIRSGASQFFSALCSRLASD-------
>tr|A0A011RE83|A0A011RE83_9PROT NAD-dependent protein deacylase OS=Candidatus Accumulibacter sp. BA-93 GN=cobB_1 PE=4 SV=1
------------------------------------VREAKEIVVFSGAGLSADSGIPTFRDG-GLWNKVDPDEVASIEGFLRNPERVWNWLLQLKKLV-
-DERQPNAGHQALARLQEIC-KQLTVITQNIDGYHSPAG--PVLEVHGTIHRLRCQ-CGFSADWEQ----AFRCPRCGA--PVRPDLVLFGEMLE---AA
ETCSMTADLFFCVGTSFTVQPAALLPVWAKR-GATVVEVNPHP-SLSALADYSIRSGASEFFTALSAKLAAR-------
>tr|A0A011Q2F5|A0A011Q2F5_9PROT NAD-dependent protein deacylase OS=Candidatus Accumulibacter sp. BA-92 GN=cobB_1 PE=4 SV=1
------------------------------------VRAAKEIVVFSGAGLSADSGIPTFRDG-GLWNKVDPDEVASIEGFLRNPARVWSWLLQLKKLV-
-DERQPNAGHQALARLQASC-KQLTVITQNIDGYHSRAG--PVLEVHGTIHRLRCQ-CGFSANWEE----AYPCPRCGA--PVRPDLVLFGEMLE---AA
EMRSLTADLFFCVGTSFTVQPAALLPVWAKR-GVPVVEINPHP-SLSAVADYSIRSGASEFFTALGAQIEAQ-------
>tr|D4H6A5|D4H6A5_DENA2 Silent information regulator protein Sir2 OS=Denitrovibrio acetiphilus (strain DSM 12809 / N2460) GN=Dacet_2829 PE=4 SV=1
------------------------------------IADNPYNVFFTGAGASTESGIPDYRSESGLWNRIDSSKLISLKGFLENPKGFYEFSGGLFAPF-
-AHAEPNVAHMFIAMLEE---ASKAVITQNIDGLHRKAG-FNICELHGSMETSSCIICGKSFST-------PECT-CGN--IVKPDIVFFGESLDVLEES
FELAAGCTLMIVAGSSLEVMPANLLPKYAKD-GALLVIINKTE-PLDYTADIVINKGIGEVFTELNNIWKTA-------
>tr|M2WCG6|M2WCG6_9NOCA NAD-dependent deacetylase OS=Rhodococcus triatomae BKS 15-14 GN=G419_08961 PE=3 SV=1
------------------------------------VRSAERVVVFSGAGMSAESGVPTFRDATGLWARFDPTELATPQAWERDPDLVWAWYEWRAAMV-
-RRVAPNAGHRAVADWARSA--QLTVVTQNVDDLHERAG--VAAHLHGSLYAPRCGGCTRPAELDDDRD-RPSCVHCGA--AVRPGAVWFGEPLA---TA
ADAAENCDLMVVVGTSGVVYPAAELPLRAVR-GATVVEVNPQR-DLTDAVTHSWRVTAAEALPILAAVR----------
>tr|A0A0N9N7Q3|A0A0N9N7Q3_9ACTN NAD-dependent deacetylase OS=Gordonia sp. QH-11 GN=ACH46_07570 PE=4 SV=1
------------------------------------IDDAANVCVFSGAGMSAESGIPTFRDATGLWANYEPADLATPSGWRRDPDLVWGWYRDRAETL-
-RTVEPNDGHRAIADLGRRK-GRVSIVTQNVDDLHERAG--VDAHLHGSLIGPRCETCPYRGDADL----APRCPRCGA--SLRPDVVWFGEILL---NA
SAAVGQCDLLIIIGTSGVIRPAANLPLLAAE-GTPIIEVNPEP-ALTPLATVHLESTAAAALPAIS-------------
>tr|D6TQK3|D6TQK3_9CHLR Silent information regulator protein Sir2 OS=Ktedonobacter racemifer DSM 44963 GN=Krac_9014 PE=3 SV=1
------------------------------------VRGAKNVAVLTGAGISAESGLPTFRDP-GLWEKFRPEDLATPEAFQRNPKLVWEWYAHRRELM-
-GLAQPNPGHAALAAIER---ATFTLITQNIDGLHQRAG--NVLELHGNIARTRCFEEDT-------LV--PHCPRCGG--LLRPDVVWFGESLE---QA
LEAAIFCDLFFSIGTSGLVEPAASLTEVARR-GATIVVLNLEV-PLASPDLYQLNGPAGQTLPELVRQAWQG-------
>tr|A1WXE9|A1WXE9_HALHL Silent information regulator protein Sir2 OS=Halorhodospira halophila (strain DSM 244 / SL1) GN=Hhal_1597 PE=3 SV=1
------------------------------------LHRAQRIVALTGAGISAESGVPTFRDA-GYWEQFDPGELATPEAFRRNPRRVWAWYAQRRRLA-
-EQAQPNAGHRALVDWER---GGLRVVTQNVDGLHQRAG--QVTELHGNIHRDRVFEGAV-------DG-APRCPCSGG--LLRPDVVWFGEALG---AA
VAAVREADLVLSVGTSSLVQPAASLPLEALE-DIPVLEVNREP-PLTPVADWSLRGSAGEILPALVGAATEA-------
>tr|A0A0D6KN63|A0A0D6KN63_9CYAN Silent information regulator Sir2 OS=Tolypothrix sp. PCC 7601 GN=FDUTEX481_08605 PE=4 SV=1
------------------------------------FSDYRNIVVLTGAGVSAASGIQPFRGQ-GLWNEINPFESADISVLETNPLAIWQLFGKLRSQL-
-ETAQPNAAHLALTNLEARL-QKFTLITQNIDGLHQRAG--NVIELHGNVNYTKCSNCSLAPYLDR----TPICQLCNS--PLRLDIVLFGEQIK---LA
KQSLRDCDLFIAIGTSGTVWPAANFVRSANY-GARTIFINLEPKPKNPYFQEEYLGRAEELLPLLFNMDITP-------
>tr|B8G5W7|B8G5W7_CHLAD Silent information regulator protein Sir2 OS=Chloroflexus aggregans (strain MD-66 / DSM 9485) GN=Cagg_0910 PE=3 SV=1
------------------------------------LRLAHHVAVLTGAGISAESGIPTFRDA-GLWSHFDPEELASPAGFARNPTLVWRWYAERRVKA-
-CAAQPNPAHYALAKLDK---PRLTLITQNIDGLHQRAG--NVIELHGSLHRARCMADGS-------LH--PHCPDCGA--LLRPDVVWFGEMLT---KA
WAATLDCDIFMSIGTSGVVEPAASLPRIALS-NATVLILNLEQ-TAARPPLFTINGKAGEILPRIVKMAFPV-------
>tr|A0A0N9LUT6|A0A0N9LUT6_9GAMM NAD-dependent protein deacylase OS=Beggiatoa leptomitiformis GN=AL038_06185 PE=4 SV=1
------------------------------------LKHSKRLAILTGAGISAESGVPTFRDA-GLWAQYNPTELATPEAFQQNPKLVWEWYAWRQQLV-
-AKAEPNAGHLALVELEH---PSLTIVTQNIDGLHQRAG--RVIELHGNINRFKCATENR-------IL-TPHCPYCNG--LIRPDVVWFGESLF---QA
LQAIERSDVLLTIGTSALVQPAATLPLKALQ-GATVIEINPET-PLTPCVHFSLRGKSGDILPKLLKSVWGD-------
>tr|A9B615|A9B615_HERA2 Silent information regulator protein Sir2 OS=Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785) GN=Haur_3171 PE=3 SV=1
------------------------------------LRQAERIAILTGAGISAESGIPTFRDA-GFWSRMKPEDLATPEAFERNPKLVWDWYAYRREMV-
-DQASPNAGHYALAKMAE---PNLTLITQNVDSLHQRAG--NVLELHGNIGRVKCSKEHV-------VI-EPRCPRCQA--LLRPDIVWFGEVLK---HA
KAACIQADVVFSIGTSGLVPPAATLPVTAIE-GAYGIEVNTDQ-YLSDTFECCLRGASGIILPALVKAAWPD-------
>tr|W6M3K1|W6M3K1_9GAMM NAD-dependent deacetylase OS=Candidatus Competibacter denitrificans Run_A_D11 GN=cobB PE=3 SV=1
------------------------------------LRHARQVAVLTGAGVSAESGVPTFREA-GLWAQYDPQELATPEAFRRNPKLVWEWYAWRQERI-
-RQAEPHAGHRALVTMEQ---PEFSLITQNVDGLHRRAG--QLVELHGNIFRAKCFSEDR-------PV-GPRCPRCGG--LLRPDVVWFGEALA---TA
QHAARTTEIFFSIGTSTLVYPAADLPFVALG-GATVVEINPQP-PLSPHVTFSLTGAAGEILPALVNQTWEA-------
>tr|I3CKV0|I3CKV0_9GAMM NAD-dependent protein deacetylase, SIR2 family OS=Beggiatoa alba B18LD GN=BegalDRAFT_3427 PE=3 SV=1
------------------------------------LRNSQEIAVLTGAGISAESGVPTFREA-GLWAQYNPEELATPQAFQRNPALVWEWYAWRRELV-
-AKAQPNQGHLALVKMGM---KNLTIVTQNVDGLHQRAG--NVIELHGNIQRFKCATEHR-------IL-TPHCPHCHG--LIRPDVVWFNENLQ---QA
LQLINRCDMLLSIGTSALVQPAASLPLVALR-GATVVEINPDT-PLTAHAQFVLQGKAGEILPQLLQVTWGS-------
>tr|A0A0M8K6V7|A0A0M8K6V7_9CHLR NAD-dependent deacetylase OS=Ardenticatena maritima GN=npdA PE=3 SV=1
------------------------------------LRNARHIVVLTGAGVSAESGIPTFREA-GLWAQYRPEELATPEAFQRHPERVWRWYEWRRSLV-
-RQAAPNPGHLALARMER---PRFTLITQNVDGLHQAAG--HVLELHGNIMRSRCSREGR-------IV-TPRCPHCGA--FLRPDVVWFGEALD---AA
QEAATDADVFLSVGTSTIVYPAAALPFDALA-GAFVVEINPAT-PLTPHAHAALRGPAGRILPALVDTVWNE-------
>tr|U3HX75|U3HX75_PSEST NAD-dependent deacetylase OS=Pseudomonas stutzeri MF28 GN=L686_11195 PE=3 SV=1
------------------------------------LRSAQHVVVFTGAGVSAESGIPTFRDATGLWERFDASSLATAEAFRADPALVWGWYEWRRMKV-
-LQAKPNPAHLAIAELARHV-PRLTLVTQNVDDLHERAG--EVIHLHGSLHQPRCFDCGQAGDASLDA--RPRCLICGG--ALRPGVVWFGESLS---AA
FEAAERCDVLISVGTSGMVYPASEVPGQAWR-GATVVHVNPQP-VTHRQREYALKGLAGEQLPKLLEQAFGR-------
>tr|Q1IB19|Q1IB19_PSEE4 Putative NAD-dependent deacetylase 1 (Regulatory protein SIR2 homolog) OS=Pseudomonas entomophila (strain L48) GN=PSEEN2337 PE=
------------------------------------LAQARHLVVFTGAGVSAESGIATFRDKHGLWERFDPVQLASADGFAADPALVWGWYEMRRAGI-
-NQARPNPAHQAIAALQAKL-PRITLVTQNVDDLHERAG--EVLHLHGRLDAFRCFSCAQPVDSALPL--RPRCKTCGG--YLRPGVVWFGEQLH---QA
FAAAEDCDLLLSVGTSGVVQPAALIPRIALQ-GATVVHVNPQP-VASHPREVTLPGKAGEILPRLLKQAFS--------
>tr|A0A0L6FQP7|A0A0L6FQP7_9PSED NAD-dependent deacetylase OS=Pseudomonas sp. 250J GN=DA83_01855 PE=3 SV=1
------------------------------------LAQARHVVVFTGAGVSAESGIATFRDKTGLWEHFDPAQLASAEGFRADPPLVWGWYQMRRAGI-
-AQATPNPAHLAIAALTARV-PKLTLVTQNVDDLHERAG--DVLHLHGRLDAFRCLDCARPADGPVAL--RPRCTRCAG--PLRPGVVWFGEMLQ---RA
FDAAQQCDVLLSVGTSGVVQPAASIPRLALA-GATVVHVNPQP-SEGHAREFALAGKAGEVLPQLMRQAFT--------
>tr|A0A0P7GG99|A0A0P7GG99_9XANT Uncharacterized protein OS=Xanthomonas sp. Mitacek01 GN=AO715_15655 PE=4 SV=1
----------------------------------------MRLVVLSGAGISAESGIPTFRDATGLWARFDAERLATEDAFRADPALVWGWYRWRAAMV-
-AAAAPNAAHIDVAGLADDG-HALTVVTQNVDDLHARGG--DVLHLHGRLLASRCIGCSARVTPDPIL--RPACVRCGE--AFRPDVVWFGESLD---AA
EAAVDACDLLIVVGTSSLVWPAAGLPERALG-GTPVLEINPHP-PLSSRATACWPVDATVGLAKLRARLRAA-------
>tr|A0A0F0DEU2|A0A0F0DEU2_9PSED NAD-dependent deacetylase OS=Pseudomonas sp. 21 GN=UB43_28200 PE=3 SV=1
------------------------------------LRKARHVVVFTGAGVSAESGIPTFRDRTGLWQRFDAASLATAEAFRADPTLVWGWYEWRRSVV-
-HRAQPNPAHLAIAALANKV-PKLTLITQNVDDLHERAG--DVTHLHGQLERPRCFDCQREPEAALPV--RPACAHCGG--PLRPGVVWFGESLD---HA
FQAAEHCDLLISVGTSGVVYPAAEIPQMAWR-GATVLHINPAP-PLHAERDFALASAAGIALPALLDAALID-------
>tr|A4V7Q9|A4V7Q9_PSEFS Putative NAD-dependent acetylase OS=Pseudomonas fluorescens (strain SBW25) GN=pQBR0149 PE=3 SV=1
------------------------------------LKCANKIVVFTGAGASAESGIATFRDATGLWERFDAQRLATAQAFKADPSLVWGWYEWRRAQA-
-QSVLPNPGHAAVAQLGSLV-SKITIVTQNVDSLHERAR--NVLHLHGSLNSPRCFECAIPMDVPDVD--RPVCPECGG--LCRPGVVWFGESLD---AA
VAAVAECDVLLSIGTSGAVYPAAELPKQALS-GAVVIHINPDR-AVSSENEISLVGKGGVILPQLLARAFN--------
>tr|A0A0A1GED9|A0A0A1GED9_9PSED Cobalamin biosynthetic protein OS=Pseudomonas sp. MT-1 GN=MT1_2350 PE=3 SV=1
------------------------------------LRSARHVVVFTGAGVSAESGIPTFRDSTGLWERFDAASLATPEAFQADPPLVWGWYEWRRMKV-
-LQAQPNPAHVAIAELARHV-PRLTLVTQNVDDLHERAG--DVIHLHGSLHQPRCFSCGERPNTPLGM--RPSCDACGA--KLRPGVVWFGESLE---TA
FAAAETCDLLISVGTSGMVYPAAEVPGLAWR-GAVVVHVNPQP-TDHSEREFALAGLAGEQLPPLVELAFGD-------
>tr|I6ZFA6|I6ZFA6_PSEST Uncharacterized protein OS=Pseudomonas stutzeri DSM 10701 GN=PSJM300_09795 PE=3 SV=1
------------------------------------LRSARHVVVFTGAGVSAESGIPTFRDSTGLWERFDAAALATPDAFRQDPALVWGWYEWRRMKV-
-LQAQPNRAHRAIAELARHV-PRLTLVTQNVDDLHERAG--DVIHLHGSLHRPRCLRCGREPDEPLGM--RPRCMHCAG--QLRPGVVWFGEHLE---RA
FAAAQACDLLLSVGTSGVVYPAAQVPELAWE-GAVVVHVNPQG-AGRREREYNLAGPAGEQLPALLAQAFGR-------
>tr|H8GL65|H8GL65_METAL NAD-dependent protein deacetylase, SIR2 family OS=Methylomicrobium album BG8 GN=Metal_0198 PE=3 SV=1
------------------------------------LLRAEHIVVFTGAGISAESGIPTFRDATGLWEHYDPHALASPTGFIADQALVWGWYEWRRMQV-
-LEAAPNDAHYAIAELASFV-ERLTVVTQNVDDLHERAG--GVTHLHGSLHHPRCFDCGSSYAFPSGL--RPRCSECQG--AIRPGVVWFGETLS---IA
EQAAMACDVFFSIGTSGLVRPASQLPERAKL-GAKIIQINATS-PLDSQVHYNFQGRAGEILPALLQSLEDL-------
>tr|A0A0A0MBU2|A0A0A0MBU2_9GAMM Sigma factor OS=Lysobacter defluvii IMMIB APB-9 = DSM 18482 GN=N791_10935 PE=3 SV=1
------------------------------------LEACTRPVVFTGAGMSAESGIATFRGSDSLWSRFRPEELATPAAFHRDPALVWGWYVYRMAQL-
-QSVQPHDGHLALARAEERW-PGLAVVTQNVDDLHEKAG--RVLHLHGELMELRCSRCERPFGGFELPI-RPHCDHCGG--LIRPEVVWFGESLD---QA
QEAIAGCDLLLVVGTSGQVEPAASLVSLARA-GARVVLIDPGT-GHAAVADVHLRGAAGKELPRLLANEGEK-------
>tr|F2NLY0|F2NLY0_MARHT NAD-dependent deacetylase OS=Marinithermus hydrothermalis (strain DSM 14884 / JCM 11576 / T1) GN=Marky_0485 PE=3 SV=1
------------------------------------LREATRVAVLTGAGISAPSGIPTFRDP-GLWKEFRIEDYATPEAYARDPERVWAWYAWRYRKI-
-QAARPNRAHELLARLEA---G-FVLVTQNIDGLHQRAG--RVIELHGNIARARCEWCDARVPLPP----FPTCPRCTS--RMRPDVVWFGEFLK---AA
ERAFAEAEVALVIGTSAAVEPAASLGRYARW-GAYLIEINPEP-PLTPLAHCALRMGAVEGLEALLAPPAED-------
>tr|E4U9C9|E4U9C9_OCEP5 Silent information regulator protein Sir2 OS=Oceanithermus profundus (strain DSM 14977 / NBRC 100410 / VKM B-2274 / 506) GN=Oce
------------------------------------LEAARRVAVLTGAGVSAESGIPTFRGA-GLWEGFRPEELATPEAYARDPEKVWRWYAMRYAQV-
-MEAEPNPAHLRLADLER---G-FLLVTQNVDGLHLRAG--RVVELHGSIARARCERCGHRQSLPP----FPVCERCGG--RMRPDVVWFGEFLE---RA
ERAFMTAEVALVIGTSAVVEPAASLGRMAKS-GAYLIEVNPEP-PLTPLADVSLRATAARGMEALVGASAPP-------
>tr|X5LG86|X5LG86_9MYCO NAD-dependent deacetylase OS=Mycobacterium vulneris GN=BN979_05294 PE=3 SV=1
------------------------------------YVGDVQVTVLSGAGISAESGVPTFRDVTGLWAKVDPYEISSVEGWQRHPEKVWAWYLWRHYMM-
-AHVQPNDGHRAVAAWQDFA----HVITQNVDNLHERAG--NVYHLHGNLFEFRCDACGSRFEGVLPE--TPVC-PCGG--LIRPSVVWFGEPLD---RS
VQAVGNADVVIVVGTSSVVYPAAGLAEAAVA-GTVVVEVNPER-PLTDSATISLRETAAGSLPHLLQRLPAL-------
>tr|A1UKH1|A1UKH1_MYCSK Silent information regulator protein Sir2 OS=Mycobacterium sp. (strain KMS) GN=Mkms_4137 PE=3 SV=1
----------------------------------------MQVTVLSGAGISAESGVPTFRDVTGLWAKVDPYEISSADGWRANPEKVWAWYLWRHYMM-
-DAVQPNNGHHAVAAWQDHA----HVVTQNVDDLHERAG--NVYHLHGSLFEFQCDACGSRFEGNLPA--APQC-PCGG--LIRPNVVWFGEALA---RS
VHAVLTADVVVVVGTSSIVYPAAGLPEMALA-GTAVIEVNPER-PLSDSATVSLRETAVGALPTLLQRLPDL-------
>tr|A0A0M2ZD72|A0A0M2ZD72_9MYCO NAD-dependent deacetylase OS=Mycobacterium elephantis GN=AAV95_17815 PE=3 SV=1
----------------------------------------MQVTVLSGAGISAESGVPTFRDATGLWAKVDPYEISSSEGWQANPEKVWAWYLWRHYMM-
-GSVQPNSGHLAVAAWQDYA----RVVTQNVDNLHERAG--KVYHLHGSLFEFRCDACHSAFEGDLPA--APVC-PCGG--LIRPNVVWFGEALE---RS
VEAVSTADLVVVVGTSSIVYPAAGLSETALA-GTVVIEVNPER-ALSDAATVSLRETAVEALPGLLQRLPAL-------
>sp|A0R2N3|NDP_MYCS2 NAD-dependent protein deacylase Sir2 OS=Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) GN=sir2 PE=1 SV=1
----------------------------------------MQVTVLSGAGISAESGVPTFRDATGLWAQVDPYEISSTDGWQRNPEKVWAWYLWRHYMM-
-ARVAPNEAHRTVAAWEDHL----RVVTQNIDDLHERAG--NVYHLHGSLFEFRCDACGSAFEGNLPE--TPVC-PCSG--LIRPSVVWFGEPLA---RS
VLAVSSADVVIVVGTSSIVYPAAGLPEAALA-GKPVIEVNPER-PLSDSATVSLRETASEALPTLLQRLPEL-------
>tr|X5L166|X5L166_9MYCO NAD-dependent deacetylase OS=Mycobacterium mageritense GN=BN978_05454 PE=3 SV=1
------------------------------------YVGDVQVTVLSGAGISAESGVPTFRDVTGLWAKVDPYEISSTDGWERHPEKVWAWYLWRHYMM-
-AAVEPNDGHRAVAAWQDYA----HVVTQNVDNLHERAG--KVYHLHGSLFEFRCDACGSPFEGDLPE--APQC-FCGG--LIRPNVVWFGEALD---RS
VLAVSNSDLVVVVGTSSVVYPAAGLPEAALA-GTAVIEINPER-PLSDAATVSLRETAATALPGLLQRLPAL-------
>tr|A0A0I9W1Q8|A0A0I9W1Q8_9MICO NAD-dependent deacetylase OS=Dermacoccus sp. PE3 GN=AA983_00705 PE=3 SV=1
------------------------------------ARTAKGVTVLTGAGMSAESGLATFRDATGLWANQDPASLATPQAWEADPARVWAWYRWRMTLM-
-TRAQPNAGHRALAEWSEAG-AHLWVVTQNVDDLHERAG--VLAHLHGSIFAVRCSRCGQDADAVG----RPVCVHCGG--LVRPGIVWFGEALD---RA
EAATLSADLVLVIGTSGIVYPAAGLPIMAHH-GVPVVEINPEE-DLSDIATATWRVPAGEALPALLTALREN-------
>tr|A0A0K0XVR9|A0A0K0XVR9_9GAMM NAD-dependent protein deacylase OS=Wenzhouxiangella marina GN=WM2015_1345 PE=3 SV=1
------------------------------------LRDSERITVLSGAGISAESGIPTFRQATGLWARYDPMRLASPEGFAEDPGLVWRWYQWRRKLV-
-DRSEPNAGHRALVELARTI-PELRLITQNVDGLHQRAG--SVIELHGNLARTVCSRTRRAIDPDW----QPSPHHPQG--LARPDVVWFGEALH---QA
CQAASDCELMLIVGTSGLVHPAAGLPRLAAS-GACLVEVNPER-ALSDSVDWRLVGPSAECLPRLVERI----------
>tr|C8PX48|C8PX48_9GAMM Transcriptional regulator, Sir2 family OS=Enhydrobacter aerosaccus SK60 GN=ENHAE0001_2332 PE=4 SV=1
------------------------------------IKYAQNIAILTGAGVSAESGISTFRDK-GLWQQYQAEYLVSIQAFEKEPALVWQWHQWWRGQI-
-ADKQPNPAHFALGEWQALA-KTWTLFSQNVDNLHEQGG--TVAKLHGNLAKNRCH-CGKPYTKAI-----LKHCECGG--LIRPDIVWFGEMLD---TA
ETAALNCDVLVSIGTSSVVYPAAGLIDLAKQ-GATVIEINPNP-HTT-AVDIVLPDNAGKILPLLVKALK---------
>tr|D7CVL4|D7CVL4_TRURR Silent information regulator protein Sir2 OS=Truepera radiovictrix (strain DSM 17093 / CIP 108686 / LMG 22925 / RQ-24) GN=Trad_
------------------------------------LARARRVAALTGAGVSAASGLPTFRGA-GFWREHRAEDLATPQAYARDPLLVWEWYAARFHAA-
-AAAAPNGAHLHLARLEAQL-D-FTLVTQNVDGLHARSG--RVLELHGNLTKSRCERCGHLDALAP----FPCCSRCGS--RARPNVVWFGEHLR---AA
AAAFSRAEVALVIGTSGVVEPAASLGRLAAQ-GAVVVEINPEP-PLTPYATLSLRQDAVSGLHALLGPLTPP-------
>tr|F6DIH6|F6DIH6_THETG NAD-dependent deacetylase OS=Thermus thermophilus (strain SG0.5JP17-16) GN=Ththe16_1402 PE=3 SV=1
------------------------------------LQEARRVAVLTGAGISKPSGIPTFRDA-GLWKNFNPLDYATPEAYARDPERVWAWYAWRIQKV-
-REAKPNPAHYALVELERRI-S-FLLVTQNVDGLHALAG--NLVELHGNILRARCEACGKRFPLPE----FPFCPACGH--RARPDVVWFGELLG---RA
ERAFAEADFALVVGTSAEVEPAASLGRIAFA-GAYLVEVNPEP-PLTSLAHLSLRTGAVEGMALLLPPPPED-------
>tr|A0A0N0BLS8|A0A0N0BLS8_THEAQ NAD-dependent protein deacylase OS=Thermus aquaticus GN=cobB_1 PE=3 SV=1
------------------------------------LEEARKVAVLTGAGISKPSGIPTFRDA-GLWKEFNPLEYATPEAYAKDPEKVWAWYAWRIAKV-
-REARPNPAHQALAELERRV-E-FLLVTQNVDGLHARAG--NLVELHGNILRARCEACGHRFPLPE----FPSCPRCGH--RARPDVVWFGEFLG---RA
VRAFSEADVALVIGTSAEVEPAASLGRIAYA-GAYLVELNPEP-PLTPLAHLSLRMGAVEGMAVLLEGL----------
>tr|A0A0A2WUP3|A0A0A2WUP3_THEFI NAD-dependent protein deacylase OS=Thermus filiformis GN=THFILI_05870 PE=3 SV=1
------------------------------------LEEARRVAVLTGAGISKPSGIPTFRDA-GLWRNFNPLDYATPEAYAKDPEKVWAWYAWRIAKV-
-REAQPNPAHYALAELERKV-G-FLLVTQNVDGLHARAG--NLVELHGNILRARCEACGRRFPLPE----FPFCPACGH--RARPDVVWFGEFLG---RA
ERAFAEADFALVVGTSAEVEPAASLGRIAFA-GAYLIEVNPEP-PLTPLAHLSLRMGAVEGMEALLSGWS---------
>tr|K7QXP0|K7QXP0_THEOS NAD-dependent protein deacetylase, SIR2 family OS=Thermus oshimai JL-2 GN=Theos_1595 PE=3 SV=1
------------------------------------LREAKRVAVLTGAGISKPSGIPTFRDA-GLWKAFNPLDYATPEAYARDPKKVWAWYAWRIAKV-
-REAEPNPAHYALARLEADL-D-FLLVTQNVDGLHARAG--RLVELHGNILRARCEACGRRFPLPE----FPSCPACGA--RARPDVVWFGELLG---KA
LRAFSEADLALVVGTSAEVEPAASLGRIAYT-GAYLVEVNPEP-PLTPLAHLSLRLGAVEGLEALYPLSSAP-------
>tr|G8NAH6|G8NAH6_9DEIN NAD-dependent deacetylase OS=Thermus sp. CCB_US3_UF1 GN=TCCBUS3UF1_6220 PE=3 SV=1
------------------------------------LREAQRVAVLTGAGISKPSGIPTFRDA-GLWRNFNPLDYATPEAYARNPEKVWAWYAWRIAKV-
-REARPNPAHLALVRLEEAL-S-FLLVTQNVDGLHARAG--SLVEFHGNLLRARCEACGERFPLPD----FPFCPRCGH--RARPDVVWFGEFLG---QA
ERAFAEADFALVVGTSAEVEPAASLGRIAYA-GAYLVEVNPEP-PLTPLAHLSLRTGAVEGLEALLNDGG---------
>tr|A0A0N0ZPJ5|A0A0N0ZPJ5_THESC NAD-dependent protein deacylase OS=Thermus scotoductus GN=AN926_08365 PE=3 SV=1
------------------------------------LKEARRVAVLTGAGISKPSGIPTFRDA-GLWKEFNPLDYATPEAYARNPERVWEWYAWRIARV-
-REAKPNPAHLALVRLEEEV-A-FLLVTQNVDGLHALAG--NLVELHGNILRARCEACGHRFLLPD----FPFCPLCGH--RARPDVVWFGELLG---KA
EKAFAEADVALVVGTSAEVEPAASLGRIAFT-GAYLIEVNPEP-PLTPLAHLSLRMGAVEGLQALGYGESGA-------
>tr|A0A085FYF8|A0A085FYF8_9BURK SIR2 family NAD-dependent deacetylase 3 protein OS=Massilia sp. LC238 GN=FG94_00146 PE=3 SV=1
------------------------------------LREARKLMVLTGAGMSAESGIPTFRDATGLWRQFDAASLATPDAFRRDPALVWGWYEWRRMKA-
-LSARPNAGHVAIARLASRM-EHLSLFTQNVDDLHERAG--DVQHLHGSLHHPRCADCARPFSLPAAA--RPSCPACGG--PVRPGVVWFNEALD---RA
FDACASCDLLIVVGTSGTVYPVAQLPEVARR-GSRVVQVNPTA-ELDRVCTWNLRGSAAQVLPALLDRTW---------
>tr|A0A086WA22|A0A086WA22_9BURK NAD-dependent deacetylase OS=Massilia consociata GN=JN27_13080 PE=3 SV=1
------------------------------------LRKARKITVLTGAGVSAESGIPTFRDATGLWQNFDAAALATPDAFRRDPALVWGWYEWRRMRA-
-LAAQPNAAHVAIARLAGRA-GHLNLFTQNVDDLHERAG--DVRHLHGSLHHPRCSGCARPFSLPAAA--RPSCPACGG--AVRPGVVWFNESLD---QA
FASCTSSDLLIVVGTSGTVYPVAQLPDVARR-GCPVVQVNPAA-ELDRACTWNLRGSAAHILPALIGRA----------
>tr|A0A0M5L193|A0A0M5L193_9ACTN NAD-dependent deacetylase OS=Corynebacteriales bacterium X1698 GN=AL705_01845 PE=3 SV=1
------------------------------------CADAAHVAILSGAGISAESGIPTYRTSSGLWEQFDPQTLATPEAWAQDHQMVWAWYLWRNSLV-
-RDVQPNAAHQALARWEHYA--DVRICTQNVDDLHERAG--QVEHVHGTLFHFICSECRSDYPHPVDI--RPVCPYCGA--PIRPDIVWFGEMLI---RS
VAAAEHCDVYLTVGTSAVVQPAATLPRIAAH-EKPVIEINPAR-PESSLCDVSLRMSASEALPLLLAARKAA-------
>tr|A0A0P6YLQ3|A0A0P6YLQ3_9CHLR Uncharacterized protein OS=Herpetosiphon geysericola GN=SE18_04290 PE=4 SV=1
------------------------------------LRAARSLTILTGAGMSAESGIPTFRDS-GLWNTFEIEQVASLAGYLQQPQAVWGWYHTHRQQI-
-LAVQPNLGHVALAQLEQ---S-VTLITQNIDALHQRAG--NVIELHGTIDTIRCSAGDHGISAWP----QPLCAVCGA--PLRPDVVWFGERLA---AA
EFASQTCDVFLAIGTSGLVAPAATFPMTARA-RARLIDLNLED-PLSRHARHRLRGPAAQLLPALVAATWPE-------
>tr|L1M7U8|L1M7U8_PSEPU NAD-dependent deacetylase OS=Pseudomonas putida CSV86 GN=CSV86_01698 PE=3 SV=1
------------------------------------LRDARHVLVFTGAGVSARSGIPTFRDAGGLWSRYDPASLATADAFRQDPALVWGWYQWRRAQV-
-LAARPNPAHLAIAELARRV-PRLTLVTQNVDDLHERAG--EVIHLHGSLHAPRCFACARAYAGSDAE--RPRCLRCNG--RIRPGVVWFGEALR---EA
LAAARACDLLLVVGTSGLVMPAAQLPQVARQ-GAKVVHVNLDA-PADGATTFTLAGDAAEILPRLLLQMADD-------
>tr|A0A0D6BG82|A0A0D6BG82_9PSED NAD-dependent deacetylase OS=Pseudomonas sp. Os17 GN=POS17_2448 PE=3 SV=1
------------------------------------LARARHLVVFTGAGVSAESGIPTFRDASGLWEQFDPAQLATPQAFRADPALVWGWYEGRRLKV-
-LEAQPNPAHLAIAELARRV-PRLTLITQNVDDLHERAG--SVLHLHGSLHTPICFACQRPWRGEPAA--RPRCSGCNG--KIRPGVVWFGEALA---AA
FKAAEDCDLLLSVGTSGLVQPAAQIPQLALQ-GARVVHINPQP-ECRSPQEYSLTGPAGQLLPQLVQRAFA--------
>tr|A0A0N0VKL6|A0A0N0VKL6_9PSED NAD-dependent protein deacetylase, SIR2 family OS=Pseudomonas fuscovaginae GN=PF66_01647 PE=3 SV=1
------------------------------------LRDARHVVVFTGAGVSAESGIPTFRDATGLWSRFDPAALATAEAFRNDPALVWGWYEWRRSKV-
-LAASPNPAHLAIAELARRV-PRLTVITQNVDDLHERAG--DVIHLHGSLHSPRCFACTRPYQGVSGP--RPRCHKCNG--KIRPGVVWFGEALQ---DA
LAAAGDCDLLFSIGTSGVVQPAAQIPQVARK-GAVVVHVNLQP-SVEGENEFALVGQAADILPRLLARMDA--------
>tr|E6WRN7|E6WRN7_PSEUU Silent information regulator protein Sir2 OS=Pseudoxanthomonas suwonensis (strain 11-1) GN=Psesu_0917 PE=3 SV=1
------------------------------------ARRFERIVVFSGAGMSADSGIPTFRSGNGLWHAFDPQQLATPQAWRRDSALVWGWYEWRRGLV-
-MQARPNPGHLAVARLQQA--LGAQVVTQNVDDLHERAG--GALHLHGSLFAPRCFDCAAPHPLMPSP--RPRCAHCGG--EVRPGVVWFGEMLT---QA
QERIATCDLLLVVGTSGVVQPAAGLVGLA-P-DAVVVEVNPQP-APGVRPMHHVPLSAAVGLPLLVEQLLRN-------
>tr|A0A0P9SDN4|A0A0P9SDN4_PSESX NAD-dependent protein deacylase OS=Pseudomonas syringae pv. castaneae GN=ALO79_00734 PE=4 SV=1
------------------------------------LSDAPDIVVFTGAGISAESGIPTYGDQTGIWAPYDPRNMETAKAFRENPPLVWGWYLWRRQQV-
-SKAAPNAAHLAVSRLAKSG-YKISVITQNIDDLHERAG--DVLHLHGSLSTPKCFACHRTAEIPPSH--EPRCVRCNG--KLRPGVVWYGEDLD---SA
IASVKSCDVLISVGTSGIVTPAADIPRTALS-GATVIHVNTED-STGAVNELMLIGKATEVLKRLCALLPSR-------
>tr|A0A0R2Y6E2|A0A0R2Y6E2_9PSED NAD-dependent deacetylase OS=Pseudomonas poae GN=TU75_25195 PE=4 SV=1
------------------------------------LLNAPKIVVFTGAGISAESGIPTYADPTGTWAPYDPRNLETAKAFRENPQLIWGWYLWRRQQV-
-AKADPNAAHLAVSRLAKMA-HNVSVITQNIDDLHERAG--NVLHLHGSLSTPKCFACHRPVEIPLPQ--EPRCVRCNG--KLRPGIVWYGEDLD---SA
IALVKSCDVLISVGTSGIVTPAADIPRLALS-GAIVIHVNTEY-SHGGQNELMLTGKATEVLTKLWSLITTK-------
>tr|D3F115|D3F115_CONWI Silent information regulator protein Sir2 OS=Conexibacter woesei (strain DSM 14684 / JCM 11494 / NBRC 100937 / ID131577) GN=Cwo
------------------------------------MRAARSVVALTGAGISVPSGIPDFRTPTGLWANVDPMEVAHIDAWRNDAARFWAFYGHRFQSL-
-RDKRPNRAHEVLAELER---IVETVITQNIDQLHERAG-ADLIELHGSIAHSSCLACGARYPL------PPRCD-CGR--PLKPDVVLFGELLAGLERA
QTLALRADLLLCIGSSLEVYPVGELPSLTLR-GGEIAILTQGP-RYDRDAVVKLDGDIVAELEALLAELSAG-------
>tr|H0E498|H0E498_9ACTN NAD-dependent protein deacetylase of SIR2 family OS=Patulibacter medicamentivorans GN=PAI11_16250 PE=4 SV=1
------------------------------------VREAGSVVALTGAGISVPSGIPDFRTPTGIWANVDPMEVAHVDVWRHDPERFWAFYGHRFASL-
-GQIEPNAAHRALAELER---HLDAVLTQNIDLLHEKAG-RDVVELHGSIAGCHCPACGHRTGL------PPRCGVCAG--VLKPDVVLFGDMLAAITRA
ERLALGADLLLCIGSSLVVFPVSELPAATLS-GGRLAVVTASE-PYDDAAAVRLGGDVVDELTGLLAALDRL-------
>tr|D2R126|D2R126_PIRSD Silent information regulator protein Sir2 OS=Pirellula staleyi (strain ATCC 27377 / DSM 6068 / ICPB 4128) GN=Psta_3856 PE=3 SV=
------------------------------------LRGAKRLVVLTGAGISAESGLATFRDA-GLWANFRAEELATPEAFEQNPKLVWDWYVWRRKLA-
-QAAKPNGAHFALVELER---PQLTIVTQNVDGLHQRAG--GVIELHGSLSRFKCSTDNE-------PV-DPRCPRCHA--FVRPDIVWFGEMLS---TA
FQVTKKCDLFFSIGTSGVVEPAASLPRRAIE-GASVMINNLDV-TASEPPLYSLQGKAGTILPELLRRAWPR-------
>tr|A0A023X3J6|A0A023X3J6_9ACTN NAD-dependent protein deacetylases SIR2 family OS=Rubrobacter radiotolerans GN=RradSPS_1336 PE=3 SV=1
------------------------------------LRRARSVCVLTGAGVSAESGVPTFRDA-GLWERYDPLELATPEAFEQNPRLVWDWYAWRRELV-
-REAEPNPAHHALAELEE---PEFVLVTQNVDGLHRRAG--QVVELHGNLGYVICASERT-------PV-EPLCPRCGS--YLRPDVVWFGETLG---EA
QAAAAGCDVFLSVGTSSVVYPAAGLASEAAR-GALVVEVNPQQ-PLSGASDHVLRAPAGTALPALVDALKD--------
>tr|E1IAP5|E1IAP5_9CHLR Silent information regulator protein Sir2 OS=Oscillochloris trichoides DG-6 GN=OSCT_0396 PE=3 SV=1
------------------------------------LQRAQSVTVLTGAGVSAESGIPTFRDA-GMWANFNPEELASPDGFRRNPKLVWEWYAWRRELV-
-QQAQPNPGHLALVELER---PTFTLITQNVDGLHQRAG--KVIELHGNIGRVTCSAEGT-------QI-EPRCPHCGA--YLRPDVVWFGEMLQ---AA
WDAAEMCDLFLSVGTSGVVEPAASLPRVARQ-GATVAVINLDV-EQNQPPIFSIHARSGEWLPALVRAAWPS-------
>tr|A0A0F9TUJ0|A0A0F9TUJ0_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_0304140 PE=3 SV=1
------------------------------------MHAAGSVAVLTGAGVSAESGVATFRGE-GLWRDRRVEEFATPEGFAADPCAVWQWYSERRQEA-
-LAAQPNAAHQALAALQQQT-R-FTLITQNVDCLHQHAG--DVLELHGSIRDMRCCRCAYRRPIG------PRCPACDQ--LLRPDVVWFGEMLD---AA
IEAATTCDLFMTIGTSAIVYPAAGLIRQAIQ-GAKTIEINLDP-PASSLVDIALHGPAGEILPALIGQRP---------
>tr|D9QQV4|D9QQV4_ACEAZ Silent information regulator protein Sir2 OS=Acetohalobium arabaticum (strain ATCC 49924 / DSM 5501 / Z-7288) GN=Acear_1385 PE=
------------------------------------IHESERTVAITGAGISTESGIPDFRSSGGLWQQENSIVL-SNDTLERNPKCFYSFGQNIFEKI-
-RAAEPNPAHYALAELEE---ELEAVITQNVDSLHQKAG-QNVLEIHGHLRSGTCLSCERKYDI------RPDCDRCSG--LIKPDIVLFGDPLDFV-QS
RKVVSEADLALVIGSSLEVAPANMLPKLAD----KQAVINLQQ-TLDQQAEVVINQKAGEVLSEVVDFINRT-------
>tr|G2SJP6|G2SJP6_RHOMR NAD-dependent deacetylase OS=Rhodothermus marinus SG0.5JP17-172 GN=Rhom172_2320 PE=3 SV=1
------------------------------------LARARSVAVLTGAGISAESGVPTFRDP-GLWERFRPEELANVQAFLRNPDLVQRWYAYRRKLV-
-REVEPNPGHYALVELER---PDFTLITQNVDNLHRRAG--RVVELHGNLLRSYCIDCGR-------PA-EVRCPACGG--LIRPDVVWFGELLE---EA
YAACERAEVFLSVGTSVVVYPAAGLPLEAKR-GAYVAEINLQP-AIADQVDALLLGKAGEILPALVAAVRQA-------
>tr|A0A0G3H492|A0A0G3H492_9CORY NAD-dependent protein deacetylase, SIR2 family OS=Corynebacterium testudinoris GN=cobB2 PE=3 SV=1
------------------------------------ARSAQRIEIFSGAGMSAESGLDTFRDATGLWSQVDPIAMASVDSWERDPEPMWAWYLWRAQRC-
-RAAEPNAGHRAIAEWAEIA--EVSVTTQNIDDLHERGG--EVTHLHGSLFDYHCSHCSRPFDGDVDY--RPTCVFCGG--LIRPGVVWFGEMLR---DA
EERMHAADLVIIVGTSGVVQPAASLPLVARE-GTPLLEISPQD-ELTRVADVSWRTTAAFGLPELVTGLQLE-------
>tr|D5NW82|D5NW82_CORAM Transcriptional regulator, Sir2 family OS=Corynebacterium ammoniagenes DSM 20306 GN=HMPREF0281_00841 PE=3 SV=1
------------------------------------IHAASHVHFFTGAGMSADSGLDTFRDATGLWQKVNPQDMASIEAWQRDPEPMWAWYLWRAHLA-
-HQSQPHAGHLAIGSLAQRS--QVSVTTQNIDDLHERSG--DVAHLHGSLVAFRCSSCHLPYPHHIEL--RPHCEECGG--LIRPGVVWFGESLD---KA
EENMRAADVVVIVGTSGSVWPAAGLPSIAHR-GTPIIEVSPHR-DLTDLATVWIEDTAAAALPAILK------------
>tr|A0A0B5D016|A0A0B5D016_9CORY NAD-dependent deacetylase OS=Corynebacterium humireducens NBRC 106098 = DSM 45392 GN=B842_00480 PE=3 SV=1
------------------------------------AREASRVEVFTGAGMSAESGLDTFRDATGLWTKVDPVAFASVDSWARDPEPMWAWYLWRGTVC-
-RRAEPNPGHRAIADWSL---VHVGVTTQNIDNLHERGG--DVVHLHGSLFDYRCTICSRPWKGEVEF--RPECPLCGN--LVRPGVVWFGEQLD---RA
EARMAAADLVVVVGTSGVVHPAAGLPLVAKH-GAKILEISPEE-ELSRIADVSWRTTAAQGLTQLVMGLTLD-------
>tr|A0A0B6TSM1|A0A0B6TSM1_9CORY NAD-dependent protein deacylase 2 OS=Corynebacterium marinum DSM 44953 GN=cobB2 PE=3 SV=1
------------------------------------ARGAGRVEIFTGAGMSAESGLDTFRDATGLWTKVDPVAFASLDSWARDPEPMWAWYLWRASVC-
-RGAEPNAGHRAIAEWAGWA-AHLGVTTQNIDDLHERGG--DVVHLHGSLFDYRCTICSRPWRGGVDY--RPACPLCGN--LIRPGVVWFGEPLD---RA
EARMLAADLVVVVGTSGVVQPAAGLPALAKQ-GARVLEISPEE-ELSRAADVSWRSTAAQGLPELVLGLTL--------
>tr|A0A0F6W486|A0A0F6W486_9DELT NAD-dependent protein deacetylase OS=Sandaracinus amylolyticus GN=cobB PE=3 SV=1
------------------------------------LRESKRTVALTGAGVSTDSGIPDFRSP-GLWAKHDPMQVASISGFRSDPAAFYGFWSERFGAL-
-GQAEPNVAHRVLAKLEAR--LVHAIVTQNIDGLHQRAG--RVLEVHGTWRTARCT-CGARFDTLR-L--RPTCDRCGG--LVKPDVVLFGEALD---EA
ERAVDRCDLLVVLGTSLEVWPVAGLAPRARA-GARVVVINREA-VADQEADLVIHAELREAMQRLARELDVT-------
>tr|H5SVE7|H5SVE7_9BACT NAD-dependent protein deacetylase OS=Candidatus Acetothermus autotrophicum GN=cobB PE=3 SV=1
------------------------------------LREAQYAVALTGAGVSTDSGIPDFRSPTGLWAQYNPMEVASIGGFRSNPARFYEFWRQRFAAL-
-ADAQPNITHRVLAELEA---SLKSVITQNIDDLHRKAG-KRVLEVHGNYTRGLCIGCKKVYTI------RPLCDECNS--LLKPDVVLFGELLDFD-QA
LDEIARCDLVLVLGTSLEVYPVAGLVPQAKQ-GARIALINRDR-PFDPIADLVIHEELQPAMTELYRIFFGA-------
>tr|F3EZV7|F3EZV7_PSEA0 Sir2 family transcriptional regulator OS=Pseudomonas amygdali pv. mori str. 301020 GN=PSYMO_19298 PE=3 SV=1
------------------------------------LANAERIVCFSGAGISAESGIPTYRDKTGLWARYHPQYLETAKAFRDNPELVWGWYLWRRQQA-
-AQAQPNAAHLALHKMVSQR-RTVCIITQNIDDLHERAG--EVLHLHGSLARPKCFACHRSSEIVQAE--LPRCDRCGG--RLRPGVVWYGEDLG---SA
LSLVKNCDVLISVGTSGIVTPAADLPEIALS-GATIIHVNIVD-GLGNPNELMIVGKATEVLSQLCTAVSLV-------
>tr|B1J7W6|B1J7W6_PSEPW Silent information regulator protein Sir2 OS=Pseudomonas putida (strain W619) GN=PputW619_2348 PE=3 SV=1
------------------------------------LRSAQHIMVFTGAGVSAGSGIPTFRDETGLWERQDPQRLETAQAFRENPALVWGWYLWRRQQV-
-MQAKPNAAHQAIHRLSGSG-RSVTVVTQNIDDLHERAG--EVLHLHGSLMRPKCFACHRFVVEPLVF--LPRCRRCNG--RLRPAIVWFGEYLG---AA
SQAARQCDILLSIGTSGVVRPAADLPDIALA-GAVVIHVNNVD-SMNGPNEIMLIGPAEKILPQLIALALT--------
>tr|A0A0Q0ECF0|A0A0Q0ECF0_PSEA0 NAD-dependent protein deacylase OS=Pseudomonas amygdali pv. ulmi GN=ALO41_01461 PE=4 SV=1
------------------------------------LLQARNITFFSGAGISAESGIPTYRDKIGLWSQYDPEDLETATAFRKSPQLVWGWYLWRRQQM-
-ALAQPNVAHRALCRMAASG-RAVSVITQNVDDLHERAG--NVLHLHGSLATPKCFACHRPAQLEKQQ--LPRCNRCGG--KLRPGVVWYGEDLD---SA
MLLVRGCDVLISVGTSGIVTPASDIPRLALA-GAKVIHVNTAD-SQRGDNEIMLIGNATDILTHLSAFLEGK-------
>tr|W2DTY0|W2DTY0_9PSED NAD-dependent deacetylase OS=Pseudomonas sp. FH1 GN=H096_16680 PE=3 SV=1
------------------------------------LLKARTITCFSGAGISAESGISTYRDPAGLWSQYDPEKLETAKAFRENPRLVWGWYLWRRQQV-
-ARSQPNVAHRAFCQMAATG-RTVSIITQNVDDLHERAG--GVLHLHGSLATPKCFACHRPAELAQDQ--LPRCRRCGG--KLRPGVVWYGEDLD---SA
MSLVRGCDILISVGTSGIVTPAADIPRLALA-GALLIHVNTED-SLGEHNEIMLIGNATGVLAQLSEFLESD-------
>tr|U2ZID4|U2ZID4_PSEAC NAD-dependent protein deacylase OS=Pseudomonas alcaligenes NBRC 14159 GN=cobB PE=3 SV=1
------------------------------------LRNCRHLLVFSGAGVSAESGIATFRDATGLWARFDPARLATPEAFVADPELVWGWYEWRRQQV-
-LRAAPNAAHRAIAELARRV-PRLTLVTQNVDDLHERAG--AVIHLHGSLHAPRCFDCAAPYAGLDTE--RPHCGVCGG--RVRPGVVWFGEALL---RA
FAAAAECDLLLSVGTSGLVYPAAQVPQIALC-SAQVVHINPQP-ISNSPREHSVLGAAGVVLPHLLHAAFAG-------
>tr|A0A0D7FA85|A0A0D7FA85_9PSED NAD-dependent deacetylase OS=Pseudomonas oryzihabitans GN=UM91_21135 PE=3 SV=1
------------------------------------LRQADEVLVLTGAGASAESGIATFREATGLWARFDPVQLATAEAFIEDPVRVWSWYEGRRAQV-
-LAAQPNPAHRALAQWSDRH-GRFHLVTQNVDDLHERAG--AVIHLHGSLHAPRCFECARPLTAPALP--LPRCPACGG--LARPGVVWFGESLE---KA
WALAERCDLCLVVGTSGLVQPAASLPGVARQ-GATVVRIDPQP-ADFS-DDWQLLGAAGVILPALLERL----------
>tr|A0A078MFX1|A0A078MFX1_9PSED NAD-dependent deacetylase OS=Pseudomonas sp. 12M76_air GN=BN1049_01463 PE=3 SV=1
------------------------------------VEKAGHILVFTGAGVSAESGIATFRDATGLWANNDPQQLATPEGFIADPARVWGWYQWRRQQL-
-LSREPNAAHRAIAALAQRV-PKVTVVTQNVDDLHERAG--AVIHLHGSLLTTRCFDCEKPAQVPVD---APSCGHCGG--MLRPGVVWFGEALD---RA
VAAAQSADLVLVVGTSGLVYPAAQIPQLAWE-GATVVHVNTEP-PVAAEREHSLVGPAGEVLAELLG------------
>tr|A0A010SNI2|A0A010SNI2_PSEFL NAD-dependent deacetylase OS=Pseudomonas fluorescens HK44 GN=HK44_002865 PE=3 SV=1
------------------------------------LRSASYVVVFSGAGVSAESGIATFRDASGLWARFDPADLATPEAFLRDPALVWGWYEWRRRQG-
-LEAQPNSAHKAIAALAARV-AKLTVITQNVDDLHERAG--GVVHLHGSLNEPRCFACNKPYRETVIL--RPRCSQCNG--KVRPGVVWFGESLV---AA
YDAARHCDLLLSIGTSGLVQPAARIPQVALD-GATVVHINTQP-TKLHDREFSLVGLAGEVLSELLEQAFKT-------
>tr|V4JA16|V4JA16_9GAMM Uncharacterized protein OS=uncultured Thiohalocapsa sp. PB-PSB1 GN=N838_16730 PE=3 SV=1
------------------------------------LRQTRHLVVFTGAGVSQESGIPTFRDATGLWAQFDAEQLATPEAFAADPELVWGWYEWRRGLV-
-LRKEPNAAHRAIAELAQKV-PRLTLITQNVDGLHERAG--DPLSLHGSLHRPYCSTCGRRHRLPDGL--RPECSACGG--LVRPGVVWFGEALA---QA
EAAVCECDLLFSVGTSSLVYPAAQLPHQAAQ-GAQVVQINPAS-SLDSVCAFNVRGSAAQVLPELVACAWPA-------
>tr|L7L425|L7L425_9ACTN NAD-dependent deacetylase OS=Gordonia hirsuta DSM 44140 = NBRC 16056 GN=cobB PE=3 SV=1
------------------------------------VRAAERIVVFTGAGMSAESGLPTFRDETGLWSRYDVSRLATPEAWDADPALVWAWYQRRRFQL-
-AAVEPNPGHRAIAALGRHR--RVDVVTQNVDDLHERGG--RVVHLHGRLAETFCDTCRLPYPVP-----HERCV-CGG--RIRPGVVWFGEHLD---RA
VDHAENCDLMLVVGTSGIVYPAAGLPQVARE-GATVAEINPNR-DLSEAADLVWRAPASTALPALLEVLSGT-------
>tr|A0A0B6WX27|A0A0B6WX27_9BACT NAD-dependent protein deacetylase, SIR2 family OS=Pyrinomonas methylaliphatogenes GN=PYK22_01300 PE=4 SV=1
------------------------------------VRGARRVFVLTGAGVSAESGVPTFRGG-AVWKGMPFNVISSAEMIERDLPEVWAWFDYRRSVI-
-ERVRPNPAHETLARWQD---D-FVLATQNIDGLHERAG--CVLELHGSIWRARCLNCEARKDLRA----GPLCSICGA--MMRPDVVLFGEFLE---RA
EEAARSCDLCFVIGTSAIVYPAAGLPEIARG-GAYLVEVNPEE-PLSALCHESLRGRAGEILPFLDRHIFGS-------
>tr|A0A081Y5A4|A0A081Y5A4_9PSED NAD-dependent deacetylase OS=Pseudomonas sp. AAC GN=FG99_24670 PE=3 SV=1
------------------------------------LRQARHLVVFTGAGVSAESGIPTFRDASGLWQRFDPAQLATPEAFAEDPALVWGWYEWRRMKV-
-LAAQPNPAHRAIAELAARV-PRLSLVTQNVDDLHERAG--AVIHLHGSLHQPRCVACGRAHDGLSTS--RPRCVHCGE--RVRPGVVWFGEMLA---EA
FAAARACDCLLSIGTSGVVQPAAMIPQLAAE-GAVVAHVNPQP-SVRGPRQFSLEGPAGVVLPALSEAAFGY-------
>tr|A0A0F7Y097|A0A0F7Y097_9PSED NAD-dependent protein deacylase 1 OS=Pseudomonas sp. CCOS 191 GN=cobB1 PE=3 SV=1
------------------------------------LAQARHVVVFTGAGVSAESGIATFRDKTGLWARFDPAQLASAEGFRADPALVWGWYQMRRAGI-
-AKAVPNAGHLAIAALAAQV-PQLTLITQNVDDLHERAG--AVLHLHGRLDAFRCLDCARPADEPVAL--RPRCACCAG--PLRPGVVWFGEMLA---QA
FAAARQCDVLLSVGTSGLVQPAASIPRMALA-GATVVHVNPQP-PCEHPRAFMLPGKAGEVLPQLLRQAFA--------
>tr|A0A0F7QUP7|A0A0F7QUP7_PSEAI NAD-dependent deacetylase OS=Pseudomonas aeruginosa GN=cobB1 PE=3 SV=1
------------------------------------LAGARRLVIFTGAGVSAESGIPTFRDAGGLWARYDPAALATPAAFADDPALVWGWYEWRRLKV-
-LGVQPNPAHRAIAALSGRI-ADTRLVTQNVDDLHERAG--DVLHLHGSLHAPRCATCAAAYRDALPD--RPRCPACGG--QVRPGVVWFGEALA---EA
FAAACECDLLLSVGTSGVVQPAARIPGLALE-GASVVHVNPQT-RTRHPREHCLVGPAGEMLPELLRRAFPG-------
>tr|A0A0Q0RSP1|A0A0Q0RSP1_PSEAI NAD-dependent deacylase OS=Pseudomonas aeruginosa GN=AOA77_09845 PE=4 SV=1
------------------------------------LAGARRLVVFTGAGVSAESGIPTFRDADGLWARYDPAALATPAAFADDPALVWGWYEWRRQKV-
-LRAQPNPAHRAIAALADRV-ADTRLVTQNVDDLHERAG--EVLHLHGSLHAPRCAGCAMAYRVPLAE--RPRCRACGG--PVRPGVVWFGEALT---EA
FAAAGECDLLLSVGTSGMVQPAARIPALALE-GASVVHVNPQP-RTGHPRERCLVGTAGEVLPALLRMAFPG-------
>tr|A0A024HM80|A0A024HM80_PSEKB NAD-dependent protein deacylase 1 OS=Pseudomonas knackmussii (strain DSM 6978 / LMG 23759 / B13) GN=cobB1 PE=3 SV=1
------------------------------------LRTTRHLVVFTGAGVSAESGIPTFRDASGLWERFDPAQLATPEAFAEDPTLVWGWYEWRRMKV-
-LAAQPNLAHHAIAELETCV-PRLTLVTQNVDDLHERAG--EVIHLHGSLHQPRCVACSMPHGTLSSA--RPRCLHCGE--RVRPGVVWFGEMLS---AA
FAAAQDCDCLLSIGTSGVVQPAAMIPQLAAE-GAVVAHVNPQP-SVHGPREFSLEGPAGVVLPALLDAAFQ--------
>tr|A5USR3|A5USR3_ROSS1 Silent information regulator protein Sir2 OS=Roseiflexus sp. (strain RS-1) GN=RoseRS_1261 PE=4 SV=1
------------------------------------LINARRVVALTGGGVAAESGIPSFREA-GHWAQYDVSELATPQAFVRNPRLVWEWYAYRRMLA-
-ERAQPGVTHYALVDLEQH--PAFTLITQSIDGLHWRAG--DLIELNGSLRRCRCF-GHIAFAWDD----GPRCVQCGS--LLRPDVVMFGEGLH---RA
RQAVEQCDVFLCVGTVGAIEPVASFPFVARR-GAFVMTIAPED-IYTLMADYVIAAQPGVIASELVRLIVGD-------
>tr|A9B616|A9B616_HERA2 Silent information regulator protein Sir2 OS=Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785) GN=Haur_3172 PE=4 SV=1
------------------------------------LRNAQSITVLTGGGLAQECGIPSFREADSRWAGYEPQELATVEAFLRNPRLVWEWFAYRRGLA-
-EAAQPSAAHYALVDLEQL--PKFKLITQATDGLHWRAG--ELIELHGNLARMRSY-GGMVDSWDE----TPRCPRTGG--YLRPDVVLYGEGVE---EA
DQA-TMCDVFLCIGTDSVVQPAASLPLHAKR-GATVIEINRQP-TFGFFTDHAFHGKLAELLPQLVAALE---------
>tr|A0A0P9DCL5|A0A0P9DCL5_9CHLR NAD-dependent protein deacylase OS=Kouleothrix aurantiaca GN=SE17_28090 PE=4 SV=1
------------------------------------LKQATRVVVITGGGMAAASNIPSFREA-GEWAQYDVSELATVQAYMRNPRMVWEWYEHRRHTA-
-ESAEPSPAHFALVDLEQH--PIFTLITQTIDGLHWRAG--DLIELNGCLRRSRCY-GHVISGWED----GPRCPHCGS--MLRPGVVMFGEGLW---SA
RAAVEQCEVFICAGDVGAIEPVASFPFAAKR-GALVLAIDAEN-IYTLMADHVIDMPVRDALPELVRLVIGD-------
>tr|A7NJL7|A7NJL7_ROSCS Silent information regulator protein Sir2 OS=Roseiflexus castenholzii (strain DSM 13941 / HLO8) GN=Rcas_1594 PE=4 SV=1
------------------------------------LSQSRRVVALTGGGVAAESGIPSFREA-GLWAQYDVSELATPQAFVRNPRLVWEWYAYRRALA-
-ERAQPGASHYALVDLEQY--PEFTLITQSIDGLHWRAG--DLIELNGSLRRCRCY-GHIAFAWDD----GPRCVQCGS--LLRPDVVMFGEGLH---RA
RQVVEQCEVFLCVGTVGAIEPVASFPFVARR-GAFVLTIAPDE-IYTLMADYVLSATPGAVMPELVQLIAGD-------
>tr|A0A0K1DYR9|A0A0K1DYR9_PSESF NAD-dependent deacetylase OS=Pseudomonas syringae pv. actinidiae ICMP 18884 GN=IYO_029095 PE=3 SV=1
------------------------------------LAAARKVVFFTGAGISAESGIPTFRDKTGVWAKHAPEKLETARAFRENPQMVWGWYLWRRFQA-
-GQAQPNAAHLSISQLASTG-KKISIITQNIDDLHERAG--NVVHLHGSLIKPICFACKRPAVLTTDQ--WPRCTRCNG--KLRPGVVWFGEDLG---VA
MVDVKNCDVLISVGTSGFVRPAADIPEIALA-GATVIHVNIAD-CLGAPNELMLMGSAAQILPALLQATTSI-------
>tr|F3HQW6|F3HQW6_PSEYM Sir2 family transcriptional regulator OS=Pseudomonas syringae pv. maculicola str. ES4326 GN=PMA4326_23301 PE=3 SV=1
------------------------------------LGAARKIVFFTGAGVSAASGIPTFRDKTGFWEKHDPEKLETARAFRENPQLVWGWYLWRRSQA-
-GQAQPNAAHLSISQLASTG-IQVSVITQNIDYLHERAG--NVVHLHGSLINPICFACKRTAVPTTDQ--WPRCIRCNG--KLRPGIVWFGEDLG---AA
LADVKNCDVLISVGTSGVVRPAADIPEIAST-GATVIHINIAD-CLGSSNELMLMGSAEQVLPALLQATPSS-------
>tr|F3DIU0|F3DIU0_PSEA0 Sir2 family transcriptional regulator OS=Pseudomonas amygdali pv. aesculi str. 0893_23 GN=PSYAE_20303 PE=3 SV=1
------------------------------------LKDARKIVCFSGAGISAESGILTYLDQPKLWAPYDPRALETANAFRESPALVWGWYLWRRRQV-
-ARAQPNAAHSVWPQMVNLG-YEVSVVTQNVDDLHERAG--DVIHLHGSLTMPKCFACHRPAELTSDQ--LPRCKRCRG--KLRPGVVWYGEDLG---NA
VSLVKNCDVLISVGTSGVVTPAADLPHIALA-GATVIHVNTVD-GAQAANEIMLVGRATVVLAKIHESLSTG-------
>tr|J3B1U1|J3B1U1_9PSED NAD-dependent protein deacetylase, SIR2 family OS=Pseudomonas sp. GM55 GN=PMI31_01501 PE=3 SV=1
------------------------------------LQKASKVVFFTGAGISADSGIPTYREKSGIWAGYDPRDLETAKAFRENPALVWGWYLWRRLRV-
-AQAEPNAAHRAIPRLANSQ-CQVSVVTQNIDDLHERAG--NVVHLHGSLAMPKCFACHRPAVVSPDQ--LPRCQRCNG--KMRPAVVWYGEDLQ---TA
VQLVKECDLLVSVGTSGIVMPAAGLPDLALA-GASVIHVNKVD-AMGEPKEFMLMGAAAEVLSMLLERIETG-------
>tr|F3ICY9|F3ICY9_PSEAV NAD-dependent deacetylase OS=Pseudomonas amygdali pv. lachrymans str. M302278 GN=PLA106_02770 PE=3 SV=1
------------------------------------LRAAKNIVFFTGAGISAESGIPTFRDNIGVWSTYDPEKLETARAFHENPALVWGFYLWRRNQM-
-SQAKPNAAHLAIQRLAATG-RNVAVITQNIDDLHERAG--DVAHLHGSLKTPKCFACGRTAELQLCQ--EPRCPRCNG--RLRPSIIWFGEDLV---SA
VATVQRCDVLFSVGTSGIVTPAAEIPQIALS-GAVVIHVNLVD-SPRTPDEIMIVGRATESLPALLSAAYGL-------
>tr|A0A0H1BST0|A0A0H1BST0_PSEDT NAD-dependent deacetylase OS=Pseudomonas sp. (strain TJI-51) GN=G1E_32980 PE=3 SV=1
------------------------------------LRDAQHIMVFTGAGVSAGSGIPTFRDRTGLWERQDPQRLETAKAFRENPALVWGWYLWRRQQV-
-MQALPNAAHQAIHRLSGSG-RSVTVVTQNVDDLHERAG--DVLHLHGSLTLPKCFSCHRSVAGSLEF--LPRCRRCNG--RLRPAVVWFGEDLG---TA
SRTARQCNVMLSIGTSGVVRPAADLPEMALA-GAVVIHVNTLD-SMNGPKEIMLIGPAEKILPDLVALALND-------
>tr|A0A0P8ZUJ0|A0A0P8ZUJ0_PSEFL Thiamine pyrophosphate enzyme, central domain protein OS=Pseudomonas fluorescens GN=AN403_5253 PE=4 SV=1
------------------------------------LQKAKKVVFFTGAGISADSGIPTYREKSGIWTGLDPRDLETAKAFRANPALVWGWYLWRRLRV-
-AQAEPNAAHLAIPRMAHSQ-RQVSVITQNIDDLHERAG--NVVHLHGSLAMPKCYACHRSAVVFPDQ--LPRCLRCTG--RMRPAVVWYGEDLQ---AA
VLLVKDCDLLISVGTSGIVMPAAGLPDLALA-GASVIHVNKAD-AMGEQRELMLIGHAAEVLPMLLEKISDG-------
>tr|A0A0F7P8Q7|A0A0F7P8Q7_9EURY NAD-dependent protein deacetylase, SIR2 family OS=Halanaeroarchaeum sulfurireducens GN=HLASA_1051 PE=4 SV=1
------------------------------------LVSADHAIALTGAGISTPSGVRDFRGENGLYGEFDQSDI-SIGRFERDPGGFWRWVAIHAEQFD
DDPVEPNPAHEALSDLEN---VLDALVTQNVDGLHHAAG-ESVLHLHGTAARSTCQDCGRTVET------APTCDECDG--VLKPDTVLFGEQLGAMKRA
RRHAEDTDVLLAAGSSLTVNPAASLPRTADR-GATVVIVNLDE-PADSLADHVLREPVEDALPDIADRVLEA-------
>tr|Q46ZJ9|Q46ZJ9_CUPPJ Silent information regulator protein Sir2 OS=Cupriavidus pinatubonensis (strain JMP 134 / LMG 1197) GN=Reut_A2070 PE=3 SV=1
------------------------------------IAQARSVFVLTGAGISAESGVPTFRDA-GLWARFDPEELASEEAYRRQPALVWEWYQHRRDLV-
-AAARPNPAHYALVALAA---KTVTLVTQNVDGLHQRAG--HVIELHGNLFANKWLNCDE----------PPRCSLCGA--LMRPGVVWFGEDLV---RA
EHAAETADLCLVVGTSGLVYPAAGLPGLARD-GARVVVVNPQP-VLDQTADVVLQAAAGASLPLLWPQSGSD-------
>tr|R7XQM8|R7XQM8_9RALS Silent information regulator protein Sir2 OS=Ralstonia sp. GA3-3 GN=C265_02734 PE=3 SV=1
------------------------------------IAAAGNIFVLTGAGISAESGVPTFRDA-GLWQQFDPEELASEDAYRRQPALVWEWYLHRRELV-
-AAVHPNPAHHALVALAA---RPFTLVTQNVDGLHQRAG--GVIELHGNLFANKWLDCNE----------PPRCNLCGA--LMRPGVVWFGEDLV---RA
EHAAQHCDLCLVVGTSGLVYPAAGLPGLARE-GAPVIVVNPQP-ALDQTADIVLSAAAGACLPLLWPPQPAP-------
>tr|V2K7H0|V2K7H0_9BURK NAD-dependent deacetylase OS=Cupriavidus sp. HPC(L) GN=B551_0207935 PE=3 SV=1
------------------------------------IAAANDILVLTGAGISAESGVPTFRDA-GLWARFDPEELATEEAYRRQPGLVWDWYQHRRALV-
-AAAQPNPAHHAIVALAA---KKVTLVTQNVDGLHQRAG--DVIELHGNLFANKWLDCEA----------GPRCIHCGA--PMRPGVVWFGEDLV---RA
EHAAQTCDLCLVVGTSGMVYPAAGLPGLAKD-GAGVIVVNPQP-ALDATADLVLAAPAGQCLPMLWDGAGA--------
>tr|A0A0C4YH52|A0A0C4YH52_9BURK NAD-dependent protein deacetylase of SIR2 family OS=Cupriavidus basilensis GN=RR42_m2645 PE=3 SV=1
------------------------------------IGEATNIMVLTGAGVSAESGVPTFRDA-GLWSRFNPEELAQEDAYRRQPALVWEWYLHRRELV-
-AATDPNPAHIALVALAA---KAVTLATQNVDGLHQRAG--DVIELHGNLFANKWLDCDP----------PPRCSLCNA--MMRPGVVWFGEELV---RA
EHAAEQCDLCIVVGTSGLVYPAAGLPGAAKD-GAHVIVVNPEP-ALDQTADIVLRGPAGVVLPLLWDGVSAA-------
>tr|I0I4X5|I0I4X5_CALAS NAD-dependent deacetylase OS=Caldilinea aerophila (strain DSM 14535 / JCM 11387 / NBRC 104270 / STL-6-O1) GN=npdA PE=3 SV=1
------------------------------------IAAAQCVAVLTGAGVSAESGVGTFRDA-GLWARFDPQQLASQEGFAADPGRVWRWYMHRLDMV-
-QRARPNPGHIALAALEA---PTFTLITQNVDDLHERAG--NVLHLHGRIERFHCNGCGL-------PY-APTCTFCTD--YVRPSVVWFGELLH---EA
QRAAETCDVFLVIGTSGVVYPAAHLPGIAKR-AAPVIEVNPEE-ALSDMADIWLSSPSGELLPRLLEAVRLR-------
>tr|G7H7Q3|G7H7Q3_9ACTN NAD-dependent deacetylase OS=Gordonia araii NBRC 100433 GN=cobB PE=3 SV=1
------------------------------------VRDAEHVTVFTGAGMSAESGIATFRGSDSLWGRFDPMRLASVDGWEDDPRLVWGWYAWRIGQL-
-GDVEPNAGHRALADLAGD--RVVEVVTQNVDDLHERAG--VVSHLHGNLLATRCSVCRAPYDGPVARD-RPACESCGG--DVRPGVVWFGEVLR---GA
VESFNRCDLVLIVGTSGIVYPAAGLPVDAVA-GVPVVEINPEP-GLTDIATHSIRATAATALPLLVSATRA--------
>tr|A0A0Q9KFN6|A0A0Q9KFN6_9MICO NAD-dependent deacylase OS=Janibacter sp. Soil728 GN=ASG73_05760 PE=4 SV=1
------------------------------------LQGARRVLVLSGAGMSAESGVPTFRDATGLWEAFDPTQLATLEAFQMDPPFVWAWYAWRMQLV-
-RGVDPNAGHVALADLARLR--EVTISTQNVDDLHERAG--VAAHLHGSLFEPRCSECGTPYEGE---V-RPTCPLCEG--DVRPGVVWFGEMLQTTETA
VEALEPGDVVLVIGTSGLVYPAAGYPAMARA-GATVIEINPHE-EISDMCHHVVREPAAEVLPALVEALHDR-------
>tr|K1E0L3|K1E0L3_9MICO NAD-dependent deacetylase OS=Janibacter hoylei PVAS-1 GN=B277_12191 PE=3 SV=1
------------------------------------VRGARRVLVLSGAGMSAESGVPTFRDATGLWEEFDASELATAEAFRLDPPFVWAWYAWRMQLV-
-RGVEPNPGHRALAELAGRR--EVTIATQNVDDLHERAG--VAAHLHGSLFELRCSDCDTPYTGD---V-RPTCPECEG--DVRPGVVWFGEVLDATEAA
IDALEPGDVALVIGTSGIVYPAAGYPAMARA-GATVIEVNPGE-EISDMCHLVVRGTAAHVLPQLVAAAR---------
>tr|A0A0P1NYS0|A0A0P1NYS0_9BACT NAD-dependent deacetylase OS=bacterium JGI-25 GN=JGI25_01505 PE=4 SV=1
------------------------------------LKSAKSVVVLTGAGISAESGVPTFRGQ-GLWKKFKPEELATFDAFIRNPELVWEWYNYRRKLI-
-QDVKPNPGHYALVELENL--PNFTLITQNVDNLHRRAG--NVIELHGNIEKNYCIKCGKRYDDVNL---EPKC-ECGG--LIRPDVVWFGEMLE---KA
EESASNCDVFFSIGTSGVVYPAASLPQIAKM-GAYTVEINIER-DLSWFMDEVIIGKSGEVLPKLVERLKEP-------
>tr|I0AGE1|I0AGE1_IGNAJ SIR2 family NAD-dependent protein deacetylase OS=Ignavibacterium album (strain DSM 19864 / JCM 16511 / NBRC 101810 / Mat9-16) G
------------------------------------ISESEKIVFFTGAGISAESGIPTFRGK-GIWNKLKPEELANFNAFLRNPKMVWEWYNHRKKII-
-HESKPNAGHFAIAEFEK---D-VVVVTQNIDNLHRRAG--KIYELHGNIERNYCINCRTSYNEE-LD--SPKC-KCGG--LIRPDVVWFGEFLD---ES
EKAAIRSDIFFVVGTSAVVYPAAGLVYTAKR-GSYIVEVNIEE-EISSISDISFFGEAGKVLPAILENVKKL-------
>tr|T0LE36|T0LE36_9BACT Uncharacterized protein OS=candidate division Zixibacteria bacterium RBG-1 GN=RBG1_1C00001G0228 PE=3 SV=1
------------------------------------LLSAKKVVILSGAGVSAESGISTFRDK-GLWEKFKPEDLATPAAFQRNPKLVWEWYAYRRKKI-
-QSVKPNPAHVAIARMEK---E-FLLVTQNVDNLHQKAG--KLVELHGNINRNKCFSCEKISSNFKPD--KPLC-PCGG--YLRPDVVWFGELLN---LA
QRASLEAELFFSVGTSALVYPAASLPFLAKE-GAFVVEINTGE-EISPAVDELLLGKAGETLPVIVEFLKRN-------
>tr|A0A0D6IA55|A0A0D6IA55_ALCXX NAD-dependent deacetylase OS=Alcaligenes xylosoxydans xylosoxydans GN=cobB_3 PE=3 SV=1
------------------------------------LARASRVTVFTGAGVSAESGIATFRDPTGLWSRFDAQALATPEAFAAQPDLVWGWYEWRRAQV-
-ARAEPNAAHHAIAALARRM-PALTLITQNVDNLHERAG--GVVHLHGSLHAPRCAACGEPAEFAAAAG-APACARCGA--AVRPGVVWFGESLD---AA
REAASQCDLFLSIGTSAMVYPAAELPLRASR-GATVVQVNPQA-PLDAHADFNLRGAAAQVLPRLLAAAGF--------
>tr|A0A0H4SSD7|A0A0H4SSD7_ALCXX NAD-dependent protein deacetylase of SIR2 family OS=Alcaligenes xylosoxydans xylosoxydans GN=Axylo_2132 PE=3 SV=1
------------------------------------LARARRVVVFTGAGVSAESGISTFRDPTGLWSRFDARALATPEAFAAQPDLVWGWYEWRRAHA-
-ARAEPNAAHRAIAALARRV-PGLALITQNVDNLHERAG--SVIHLHGSLHAPRCSACGQAAAFASPP--APACVHCGA--PIRPGVVWFGESLS---QA
LDAARDCDLFLSIGTSALVYPAAELPLRALR-GATVAQVNPAA-PLDAHAHFNLRGAAAEVMPRLLAAAGF--------
>tr|N2J7J2|N2J7J2_9PSED Uncharacterized protein OS=Pseudomonas sp. HPB0071 GN=HMPREF1487_07348 PE=3 SV=1
------------------------------------IRDAQHVVFFTGAGVSAESGIPTFRDATGLWATFDATELATPEAFEADPALVWGWYEWRRMKV-
-LKAQPNPAHLAIARLAQHF-PRATVVTQNVDDLHERAG--DVLHLHGSLHQPRCFACGTYS-FEREI--RPRCSRCNG--FIRPGVVWFGESLQ---QA
FDAAAQCDVLFSVGTSGVVYPAAQMPHIARD-DAAVVHINPQP-SGVHSDDWTLIGAAGDLLPKLEREVFS--------
>tr|A0A0D9ASP4|A0A0D9ASP4_PSEST NAD-dependent deacetylase OS=Pseudomonas stutzeri GN=UF78_09770 PE=3 SV=1
------------------------------------LRQARHVVVFTGAGVSAESGIPTFRDSTGLWARFDATSLATPEAFQADPALVWGRYEWRRMKV-
-LQAQPNAAHLAITELARQV-PRLTLVSQNVDDLHERAG--EVVHLHGSLHQPRCCKCGESPKQPLDM--RPSCTICSG--LLRPGVVWFGENLA---AA
FQAAETCDLLISVGTSGMVYPAAEIPGLAWR-GAVIVHVNPLP-RQHREREYTLAGPAGEQLPALVAQAFGD-------
>tr|H8Z7V4|H8Z7V4_9GAMM NAD-dependent protein deacetylase, SIR2 family OS=Thiorhodovibrio sp. 970 GN=Thi970DRAFT_04646 PE=3 SV=1
------------------------------------LRQSQHLVVFTGAGVSRESGIPTFRDATGLWSQYEPEDLAMPDAFVRDPSLVWGWYEWRRALV-
-ARCEPNPAHLTIAALANRV-PKLTLITQNVDGLHARAG--DVLELHGSLERPRCFDCGTHCPP--DA--RPTCVQCGG--FIRPGVVWFGEALD---RA
KRAAQACDLMLSVGTSGLVYPAASLPKEAVF-QIPVVQINPEP-ALDETMWHNLHGEAGVVLPSLLKSAWPD-------
>tr|A1HLU5|A1HLU5_9FIRM Silent information regulator protein Sir2 OS=Thermosinus carboxydivorans Nor1 GN=TcarDRAFT_2488 PE=4 SV=1
------------------------------------WRSANNIVVFTGAGMSTESGLPDFRS--GLWKD-RPETLATLAALKAKPDEFYFFYQWRIARL-
-WEVQPNPGHLALAELAQA--FVTKLVTQNVDGLHQRAG--GVAELHGTLRTVSCI-CGSQYDSRQ-M--HCYCPRCQG--QLRPDVVLFGESLT---EA
VRWSRKADFFVVIGSSLVVSPANYLPQLAVE-GAKLLIINSDS-PLDDAAAWVIREKAGEVLTGIKELILRM-------
>tr|A0A0M7IYJ5|A0A0M7IYJ5_9BURK NAD-dependent deacetylase OS=Achromobacter sp. GN=cobB_3 PE=4 SV=1
------------------------------------LREAREVVVITGSGLGVASGLPASRDG-GLWSQHDPGDLATAEGFRRDPASVWAWNSVRRVRA-
-SRAMPNAAHWAIGELAKV--PLMTVITQNGDNLHERAG--RAIYLHGRLDDAWCP-CGVPHVSQP-Y--HPACRLCGA--FVRPGRLWHGERPA---TC
HILATSANLVLTVGTSCQSPAAAELCYAALA-GAKLVQINPNS-SMDRLASHNLRGKAEILLPLLLAYAWPR-------
>tr|A0A0Q8JV85|A0A0Q8JV85_9BURK Silent information regulator protein Sir2 OS=Achromobacter sp. Root170 GN=ASD87_23690 PE=4 SV=1
------------------------------------LRDARLVVVLTGSGLNPASRLPQSRDG-GLWARYDAAALATDEGFRRDPALVWAWHEERRRRA-
-LAATPNAAHRAIAALAER--PGTFVVSQNGDTLHERAG--RILHLQGRFDQPRCS-CAMPHTLTA-P--YPACRICGG--LVRPGRLWHGEAPA---VA
KGLAANADLVLTAGTSCQTSAAAELCYEAMG-GAQLVQVNPNP-MLDRVASHSIRGPAEKVLPLLLARAWPG-------
>tr|A0A0Q8BW30|A0A0Q8BW30_9BURK Silent information regulator protein Sir2 OS=Achromobacter sp. Root565 GN=ASD71_14765 PE=4 SV=1
------------------------------------LRAARLIVVLTGSGLNPASRLPQSRDG-GLWARYDAAALASAAGFQNDPSLVWAWHEERRRRA-
-LLATPNAAHRAIATLAEH--PGTFVVTQNGDTLHEQAG--RILHLHGRFDQPRCS-CGMSHTLSA-P--YPACRICGN--LVRPGRLWHGEAPP---VA
KGLAANADLVLTAGTSCQTSAVAELCYEAVG-GAQLVQINPNP-TLDRVASHCIRGAAEKVLPLLLARAWPG-------
>tr|H0F9R0|H0F9R0_9BURK Silent information regulator protein Sir2 OS=Achromobacter arsenitoxydans SY8 GN=KYC_17578 PE=4 SV=1
------------------------------------VRAARNIVVLTGSGLNPASRLPLARDG-GLWARYDSAALATEEGFRRDPALVWAWHEERRRRA-
-RLAAPNAAHRAIAELAVR--PGAFVVTQNGDTLHERAG--RILHLLGRFDQPRCS-CAMPYTLAA-P--FPACRICGN--LVRPGRLWHGEPPD---IA
KGLAAAADLILAVGTSCETPAAAEFCYAAMA-GAELVQINPNP-LLDRVAAHNIKGPAEKILPLLLARAWPG-------
>tr|C5A6F9|C5A6F9_THEGJ NAD-dependent protein deacetylase, Sir2 family (NpdA) OS=Thermococcus gammatolerans (strain DSM 15229 / JCM 11827 / EJ3) GN=npd
-------------------------------------AKAKFAIAFTGAGISAESGVPTFRDA-GLWRNYKPEELATPEAFRRNPKLVWEFYKWRMRLI-
-AKARPNRAHLALARLEK---I-KAVITQNVDDLHREAG--NLIELHGNIFRVRCTSCAYRENLKESGL-SPRCPRCGS--LLRPDVVWFGEPLD---RA
FELASKADVVLVIGTSGVVYPAAYIPYVVKE-GGRVIEINPKR-GITPIADVFIPKPAGEGMEGILRGVEAF-------
>tr|G0HKE0|G0HKE0_THES4 NAD-dependent deacetylase OS=Thermococcus sp. (strain CGMCC 1.5172 / 4557) GN=GQS_00840 PE=3 SV=1
-------------------------------------ARSRFAIAFTGAGISAESGVPTFRGF-GLWKKHRPEELATPEAFRKDPYLVWEFYRWRMGLI-
-RKARPNRAHYALAELEE---L-KAVITQNVDDLHREAG--NLIELHGNIFWVKCTSCGYGEYLKESGL-EPKCPDCGS--LLRPDVVWFGEPLS---EA
FRLAERADVVLVIGTSGVVYPAAYIPQIVKE-GGRVIEINTEE-GITPIADVFLRCPAGEAMEKLMTRIKGL-------
>tr|A0A097QUX8|A0A097QUX8_9EURY NAD-dependent protein deacylase OS=Thermococcus eurythermalis GN=TEU_07910 PE=3 SV=1
-------------------------------------ARSKFAIAFTGAGISAESGIPTFRGF-GLWKRYRPEELATPEAFRRDPHLVWEFYRWRMRKI-
-LRAKPNPAHYALARLEE---L-KAVITQNVDDLHREAG--NLIELHGNIFRVRCTSCDYRENLKGSGV-SPRCPRCGS--LLRPDVVWFGEPLE---KA
FNLAERADAVIVVGTSGVVYPAAYIPYIVKE-GGRVIEVNVER-GVTPVADVFLRGKAGEVLPKLVKLVEGL-------
>tr|I3RES8|I3RES8_9EURY NAD-dependent deacetylase OS=Pyrococcus sp. ST04 GN=Py04_1164 PE=3 SV=1
-------------------------------------ASSKSAIAFTGAGISAESGVPTFRGR-GLWKRYRPEELATPEAFRTNPKLVWEFYKWRIKKI-
-LEAKPNPAHYSLVELEK---L-KAVITQNVDDLHREAG--NLLELHGNIFRVRCTSCNYKEYLKESGI--PRCPKCGA--YLRPDVVWFGEPLE---KA
FKLAETADVVIVVGTSGVVYPAAYIPYIVKE-NGTVIEINVQE-GITPIADFFLRGKAGVILPKLVDEVRRI-------
>tr|I3ZWI2|I3ZWI2_9EURY NAD-dependent deacetylase OS=Thermococcus cleftensis GN=CL1_1871 PE=3 SV=1
-------------------------------------ARSRFAIAFTGAGISAESGVPTFRGF-GLWKKHRPEELATPEAFEKDPHLVWELYRWRMNLI-
-RKARPNSAHHALAELEE---L-KAVITQNVDDLHREAG--NLIELHGNIFRVRCTSCSYRENLKESGL-EPRCPRCGS--LLRPDVVWFNEPLK---EA
FKLAERADLVLVIGTSGVVYPAAYVPQIVKE-GGKVIEINPEE-GITPIADVFLRCPAGQAMEKLMPRIKEL-------
>tr|A0A075JG68|A0A075JG68_9MICO NAD-dependent deacetylase OS=Dermacoccus nishinomiyaensis GN=HX89_04155 PE=3 SV=1
------------------------------------ARDARDVVVLTGAGMSVESGIPTFRDATGLWERHDPEELATIDAWERDPDFVWAWYRWRAKLI-
-RDVQPHVGHRALADWADAE-ANLWIVTQNIDDLHERAG--VLAHLHGSIFALRCSECDTPFDEADDAL-RPRCPVCGA--AVRPGVVWFGEELE---HA
EAALEHADLVLSVGTSGVVQPAAGLPYRPLT-GVPVVEINPAE-ELSDDATLVWRAPAAAALPALVSALRGE-------
>tr|E3BBB8|E3BBB8_9MICO Transcriptional regulator, Sir2 family OS=Dermacoccus sp. Ellin185 GN=HMPREF0321_1104 PE=3 SV=1
------------------------------------ARDARDVVVLTGAGMSVESGIPTFRDATGLWERHDPEELATIDAWERDPDFVWAWYRWRAKLI-
-RDVQPNVGHRALADWADAE-ANLWIVTQNIDDLHERAG--VLAHLHGSIFALRCSECDTPFDEADDAL-RPRCPVCGA--AVRPGVVWFGEELE---HA
EAALERADLVLSVGTSGVVQPAAGLPYRALT-GVPVVEINPAE-ELRRRRDARLACARRRRAARARLGTPG--------
>tr|B9MIQ5|B9MIQ5_ACIET Silent information regulator protein Sir2 OS=Acidovorax ebreus (strain TPSY) GN=Dtpsy_1612 PE=3 SV=1
------------------------------------VRDARRIAVLTGAGISAESGVPTFRDA-GYWAQFNPMEMASETGFRAQPARVWDWYAHRRGLL-
-AGVQPNAGHRALAAFAQ---GRLTLITQNVDGLHQRAG--DVLCLHGDLTADRWLDRPR-------AC-PPRCPTCGN--LVRPGVVWFGEALP---AA
QQAAQSCELMLVVGTAGAVYPAAGLAHQARH-GARVVVVNTAA-ELDGIAHAVLRGPAARLLPLLLDGPPMV-------
>tr|A0A0P7CV89|A0A0P7CV89_PSEPU NAD-dependent deacetylase OS=Pseudomonas putida GN=HB13667_09820 PE=4 SV=1
------------------------------------LRRSKRVVFFTGAGISADSGIPTFRDKTGLWAKHDPQRLETADAFRKNPALVWSWYLWRRQQV-
-GQAKPNLAHLSIPRIADAG-WNVSVVTQNIDDLHERAG--SVIHLHGRLMDVKCFGCHRPAELSPDQ--MPRCTRCNG--RLRPGVVWFRENLD---SA
VRLVEACDLLISVGTSGVVMPAAGIPDMALA-GATVIHVNLDD-GMDGAEEIMLVGPAGVVLPALLQAAGVA-------
>tr|A0A0Q0HU91|A0A0Q0HU91_PSESX NAD-dependent protein deacylase OS=Pseudomonas syringae pv. spinaceae GN=ALO94_01906 PE=4 SV=1
------------------------------------LRAARRVVVFTGAGISAESGIPTFRDKSGLWSVYDSRQLETADAFRENPGLVWGFYLWRRQQA-
-KSAEPNAAHLALSRLAATE-RHLAVVTQNIDDLHERAG--EVIHLHGSLEVPKCFACARPAKLTMTQ--EPRCLRCNG--RLRPGIVWFKEDLG---AS
MAMVRQCDVLISVGTSGVVTPAADIPEIAHT-GATVIHVNLVD-SLGGSRELMLIGKASEVLPTLVTSAQ---------
>tr|A0A0J6IV13|A0A0J6IV13_9PSED NAD-dependent deacetylase OS=Pseudomonas sp. DSM 28140 GN=TU87_12760 PE=3 SV=1
------------------------------------LRLAKKVVFFTGAGVSAESGIPTFRDKTGLWSIHDPQRLETANAFRDNPALVWGFYLWRRHQV-
-QQAQPNAAHSMVQKLSATD-REVYVVTQNIDDLHERAG--DVNHLHGSLEDPKCFACNRFSRLTSDD--EPRCRRCNG--RLRPGVVWFGEALG---AA
MNRVRDCDVLISVGTSGIVTPAADIPEIAHS-GATVIHVNLED-SQNGRNELMLIGRATEVLTSLFLAITTH-------
>tr|A0A098FXD4|A0A098FXD4_9PSED NAD-dependent protein deacylase OS=Pseudomonas xanthomarina GN=cobB PE=3 SV=1
------------------------------------LQSARSVVFFTGAGISAESGIPTFRDKTGLWARYDPQRLETAEAFRANPALVWGWYLWRRYQT-
-TQAQPNAAHLVPSRLAATG-RQVSVVTQNIDDLHERAG--GVVHLHGSLAQPKCFACHRPAELSEEQ--EPRCRRCNG--KLRPAVVWFKEDLA---AA
IEMVNTCQVLVSVGTSGIVTPAADIPEIALA-GATVIHVNLVD-SLDSANELMLIGSASEVLPALLKAAFPP-------
>tr|A0A059KFL9|A0A059KFL9_9BURK Silent information regulator protein Sir2 OS=Sphaerotilus natans subsp. natans DSM 6575 GN=X805_41360 PE=3 SV=1
------------------------------------LREASSVCVLSGAGMSAESGIPTFRDATGLWANFDPMQLASEAGFRADPQRVWDWYQMRRDGV-
-RQAAPHAGHVALARYAARH-GRLTILTQNVDDLHQRAA-ARIVALHGSILSDRWLDACPRDEDLMRR--PPRCPDCGN--RLRPGVVWFGESLR---AA
EEAASACDVMLVVGTSGTVWPAAGLAARARH-GAHVVILNTQA-EIDDEAHIVLTGSAATLLPRLLDPL----------
>tr|B1Y0R3|B1Y0R3_LEPCP Silent information regulator protein Sir2 OS=Leptothrix cholodnii (strain ATCC 51168 / LMG 8142 / SP-6) GN=Lcho_1904 PE=3 SV=1
------------------------------------LRHAGRICVFSGAGMSAESGIPTFRDA-GLWARFDPMQLASAEGFRADPAQVWDWYAMRREGV-
-RQAQPNAGHVALAAYAR---GRLRIVTQNVDDLHQRAG--EVIRLHGDILADRWLDPCAHAGAADAPC-DPRCRHCGN--LLRPAVVWFGENLD---AA
EAAVSEADVLLVVGTSGSVWPAAGLVARARH-GAHVVIINPQA-EIDEEAHLVLSATAARMLPRLFDPL----------
>tr|K6UMU8|K6UMU8_9MICO NAD-dependent deacetylase OS=Austwickia chelonae NBRC 105200 GN=cobB PE=4 SV=1
------------------------------------AQEAEHVTVLTGAGMSAESGVPVFRDAKALWGRADPDEVATAEAWMHDPDLVWAWHWWLARLI-
-GRCTPHDGHRALAEWARHT--RVDVVTQNVDDLHERAG--QALHLHGSLFTFSCESCARPYDLPVP---RPSCPGCAA--NVRPDVVLFGERLG---RA
VDLMLTTDLVLVVGTSGVVQPAASLPDIARG-GTTVVEINPQH-ELSWGGDLCWREDAGRALPALVEALGFP-------
>tr|D7WBM2|D7WBM2_9CORY Transcriptional regulator, Sir2 family OS=Corynebacterium genitalium ATCC 33030 GN=HMPREF0291_10511 PE=3 SV=1
------------------------------------VGDAKRVEVFTGAGMSADSGIATYRDATGVWENVDPQAMASIDAWARDPEPMWAWYLWRARLA-
-SRAEPNAGHLAIAEWGRRE--RVTVTTQNIDNLHERAN--DIVHLHGSLFEFRCSICSRPYKGEIEL--KPSCPLCGN--LVRPGVVWFGEPLK---EA
ERRMVEADLVVIVGTSGVVFPAAGLPLLAHE-GTPIIEVTPMH-ELSRISNVTLVDTAAKALPELLRGPRLD-------
>tr|A0A0F6TAA3|A0A0F6TAA3_9CORY NAD-dependent protein deacetylase, SIR2 family OS=Corynebacterium camporealensis GN=cobB2 PE=3 SV=1
------------------------------------LNDAQRIHIFSGAGMSAESGLDTYRDATGVWSHVDPQAMASIDAWARDPDPMWRWYKHRAKIA-
-AAATPNAGHLAIANCS-----RTSVTTQNIDNLHEKAG--DVIHLHGSLFEYRCSMCARPYKGDTDV---PACPLCGN--LVRPGVVWFGEPLK---AA
EEAMTLADAVIIVGTSGVVYPAAGLPMLAS---APIIEVSPAR-DLTHLTTAYIQGTAGTILPEILPD-----------
>tr|A0A0G3GTU0|A0A0G3GTU0_9CORY NAD-dependent protein deacetylase, SIR2 family OS=Corynebacterium epidermidicanis GN=CEPID_05535 PE=3 SV=1
------------------------------------LADARRVVAFTGAGMSAESGLDTYRDATGLWENVDPQAMASIDAWARDPDPMWAWYLWRARLA-
-AEAQPNAGHRALAP--------IPIVTQNIDNLHERGG--EVVHLHGSLFSFRCTICARPFRG-VEL--RPACPLCGN--LIRPGVVWFGEMLD---RA
EDLISSCDALLVVGTSGIVQPAATLPLLA----PAMIEISPQE-NLTRFASYSWRTTAAVGLPQLESFLTTP-------
>tr|U2GCV6|U2GCV6_9CORY NAD-dependent deacetylase OS=Corynebacterium pseudodiphtheriticum 090104 GN=N579_00545 PE=3 SV=1
------------------------------------LADAKQVEVFTGAGMSADSGIATYRDATGLWENVDPQAMASIDAWHRDPETMFAWYLWRAHLA-
-QRAEPNAGHRALAAAR-----KVTVTTQNIDNLHERAG--DVAHLHGSLFEFRCTDCATPYREQIAL--KPECRECGG--LIRPGVVWFGEPLN---KA
ERRMSTADALLIVGTSGVVYPAAGLPVTAYR-GIPIVEVSPQP-DLSQLASVIVTATAAEALPRILSGRITS-------
>tr|S5TG56|S5TG56_9CORY NAD-dependent deacetylase OS=Corynebacterium maris DSM 45190 GN=B841_00875 PE=3 SV=1
------------------------------------VRDAARVEVFTGAGMSADSGIATYRDATGLWENVDPQAMASIDAWARDPEPMYAWYLWRRSLV-
-AQAHPNAGHAALADWAAVD--DVTVTTQNIDDLHERAG--DVAHLHGSLFDFRCSICSRPWRGQVPQ--SPTCPVCGN--LVRPGVVWFGEPLK---LA
EQRMQEADLVVIVGTSGVVQPAASLPLLARE-GTPIIEVSPQR-DLTPVATVFVEGTAAQALPQLVDAAG---------
>tr|A0A0B6EZS5|A0A0B6EZS5_9CORY NAD-dependent protein deacetylase, SIR2 family OS=Corynebacterium singulare GN=cobB PE=3 SV=1
------------------------------------LSDATHVEVFTGAGMSADSGIATYRDATGIWENVDPVAMASISAWRSDPEPMFAWYLWRAQLA-
-QRAEPNAGHRAIAAAR-----GMTVTTQNIDNLHERAG--DVVHLHGSLFAFRCTECDTPYDEDIAF--SPECPVCGG--LVRPGVVWFGEALD---EA
ERRMSTADALLIVGTSGVVYPAAGLPQIAHA-GIPIVEVTPQP-DLSPLADVMVTATAAEALPRILAGRIDG-------
>tr|A0A095YMU6|A0A095YMU6_9CORY NAD-dependent deacetylase OS=Corynebacterium tuscaniense DNF00037 GN=HMPREF2129_04520 PE=3 SV=1
------------------------------------VDRAHRVEVFTGAGMSADSGLATYRDATGIWENVDPTAMASIDAWAKDPDTMWAWYLWRARLA-
-SQAQPNAGHLALAKWATHT--LLTVTTQNIDNLHERAG--DVVHLHGSLFAFRCSICSRPYKGKVAL--KPQCPLCGN--LIRPGVVWFGEPLC---EA
ERRMVEADLVVIVGTSGVVYPAAGLPRLAHE-GTPIIEVTPME-DLTPLATVTLVDTAAKALPALIANLD---------
>tr|M1NUM9|M1NUM9_9CORY NAD-dependent deacetylase OS=Corynebacterium halotolerans YIM 70093 = DSM 44683 GN=A605_01020 PE=3 SV=1
------------------------------------ARRARTIEVFTGAGMSAESGLVTFRDKTGLWSKVDPAAFASIESWAKDPEPMWAWYLWRSKLA-
-GQADPNAGHRAIGDWGELD-ERVGVTTQNIDNLHERGG--DVVHLHGSLFDYRCSICSRPWEGEVEV--RPACSLCDN--LVRPGVVWFGESLR---LA
EQRMREADLVVIVGTSGIVQPAASLPLIAAE-GTPLLEISPEE-ELSRLADVSWRTTAAAGLPELVMGVKVD-------
>tr|I0HCY2|I0HCY2_ACTM4 Uncharacterized protein OS=Actinoplanes missouriensis (strain ATCC 14538 / DSM 43046 / CBS 188.64 / JCM 3121 / NCIMB 12654 / NB
------------------------------------LGDARRVVVFTGAGISAESGVPTFRDATGLWERFDAQSLATPQAFQDQPDLVWGWYEWRRHRV-
-STVSPNPGHRAVAAIESRV-PSTVVITQNVDDLHERAG--DPVHLHGSLFAPRCSGCGEVALPPA----RPACVRCHG--LVRPGVVWFGEALA---AA
ARAASACDVLLTVGTSGMVYPAAEIPRIAAR-GAAVIQVNPHA-PMDSVALVNLRGSAGRILPELVTKAWPD-------
>tr|R4LJT8|R4LJT8_9ACTN Silent information regulator protein Sir2 OS=Actinoplanes sp. N902-109 GN=L083_2434 PE=3 SV=1
------------------------------------LAQARSVVVFTGAGVSAESGIPTFRDVTGLWERFDAQALATPQAWAADPDLVWGWYEWRRTVV-
-GRARPNAAHRAIAAIEAAK-PGTVVVTQNVDDLHEQAG--APIHLHGSLTAPRCARCG-PR-PPDGP--RPVCERCGG--AVRPGVVWFGEALA---AA
AEAAASCDLLLTIGTSGLVYPAAEIPQVAAR-GAWVIQVNPRP-PLDEVATVNLRGPAAEILPALTALTS---------
>tr|U5W0R0|U5W0R0_9ACTN Silent information regulator protein Sir2 OS=Actinoplanes friuliensis DSM 7358 GN=AFR_22815 PE=3 SV=1
------------------------------------LAGARRVVVFTGAGVSAESGIPTFRDSTGLWERFDAQALATPEAFRADPALVWGWYEWRRTAV-
-SRASPNAAHRAIATVEARH-PGTVVITQNVDDLHERAG--APLHLHGSLFAPRCADCG-PAARPDGT--RPACAHCAG--PVRPGVVWFGEALD---RA
VEAAASCDLLLTVGTSGLVHPAAEIPHVAAR-GAAVVQINPQP-PLDAVADVNLHGAAAEILPLLTR------------
>tr|A0A0A6UL09|A0A0A6UL09_ACTUT NAD-dependent deacetylase OS=Actinoplanes utahensis GN=MB27_15370 PE=3 SV=1
------------------------------------LAKARTVVVFTGAGMSAESGVPTFRDATGLWARYDAQALATPQAFADDPDLVWGWYEWRRSLI-
-ERVHPNLGHEAVAAIEDRA-PRTVVVTQNVDDLHERAG--APIHLHGSSFAPRCAGCS-PAPVTASR--RPRCGDCGG--LIRPGVVWFGEALD---AA
VQAATECDVLLTIGTSGLVHPAAEIPVVAAR-GATVIQVNPQP-PLDEVAAISLHGTAATVLPALVAAAWPT-------
>tr|G8S8W8|G8S8W8_ACTS5 NAD-dependent deacetylase OS=Actinoplanes sp. (strain ATCC 31044 / CBS 674.73 / SE50/110) GN=ACPL_5529 PE=3 SV=1
------------------------------------LARAGHVVVFTGAGISAESGVPTFRDATGLWSRFDAQALATPQAFAEDPDLVWGWYEWRRRLV-
-QRVRPNHGHLAVSRMAAHL-PRLTVITQNVDDLHERAG--APLHLHGSLFTPRCASCS-PAPLPPPI--RPRCRHCTG--PIRPGVVWFGEPLY---SA
VRAASACDVLLTIGTSGLVYPAAEIPRLAAR-GAAVLQINPQP-PLDPIATVNLPGPAAEILPTLVDTTWP--------
>tr|F4FE61|F4FE61_VERMA Silent information regulator protein Sir2 OS=Verrucosispora maris (strain AB-18-032) GN=VAB18032_19140 PE=3 SV=1
------------------------------------LGQARRTVVFTGAGMSAESGVPTFRDATGLWQRYDAQQLATPEAFDADPDLVWGWYEWRRAVV-
-ARARPHPGHLAVAAIEARA-PHSVLITQNVDDLHERAG--APLHLHGSLFAPRCSACA-PASTGD-P--RPRCDRCSA--PIRPGVVWFGEALP---AA
AEAAASCDVLLTVGTSGLVYPAAEIPHVAAR-GATVIQVNPEP-PLDQVSDINLRGPAARVLPTLVDAAWGG-------
>tr|A4X8W0|A4X8W0_SALTO Silent information regulator protein Sir2 OS=Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440) GN=Strop_2870 PE=3
------------------------------------LRDARRVVIFTGAGISAESGVPTFRDDTGLWARFDAQQLATAEAFHADPDLVWGWYEWRRARV-
-RRAEPNSGHLAITTIESRI-PDSTVITQNVDDLHERAG--ATIHLHGSLFAPRCMAAAAPATFPDQP--RPRCASCRE--LVRPGVVWFGEALA---AA
AEAATACDVLLTVGTSGVVYPAAEIPRIAAS-GATVIQVNPQP-PLDRIAAINLRGSAAQVLPTLVAAAWR--------
>tr|A0A0Q6JKI7|A0A0Q6JKI7_9NOCA NAD-dependent deacylase OS=Rhodococcus sp. Leaf258 GN=ASH03_18550 PE=4 SV=1
------------------------------------VRSASRVAVLTGAGMSAQSGVPTFRDATGLWERYSPEELASPDAFVRDPDLVWAWYRRRAQLV-
-AASSPNAGHVALAQWQRSA-QTVEIATQNVDDLHERAG--VLAHVHGTLAAVRCSICEEPFEGP---V-RPACGLCGS--PVRPGVVWFGEPLA---AV
AASVEAADAVLVVGTSGVVYPFAGLPAQARS-GAVVIEINPDE-AVSDMAHHVWRATAADSLPALVAAVTEQ-------
>tr|A0A0H4T9Q8|A0A0H4T9Q8_9BACT Silent information regulator protein Sir2, NAD-dependent deacetylase OS=uncultured Gemmatimonadetes bacterium Rifle_16ft_4_mini
------------------------------------------MVVFTGSGMSQESGVPTFRDETGLWARFEPEELATPEAFRRHPGRVFAWYLWRWRAI-
-RAAVPHAGYRALVELEERF--RLTIVTQNVDGLHARAG--AVIELHGSLVAFRCFDAGHPYDARRLD--EPRCDRCGS--PIRPGVVWFGEPLE---AA
RAEVEACDALLVVGTAALVYPAADLAWVGAT-GIPVIEINPQP-PLSSHVALAWRAGAGVALPELASALQAN-------
>tr|L7UAI1|L7UAI1_MYXSD NAD-dependent deacetylase OS=Myxococcus stipitatus (strain DSM 14675 / JCM 12634 / Mx s8) GN=MYSTI_02105 PE=4 SV=1
------------------------------------ATDWRNIVVLTGAGISVASGLPTYRGP-GLWTRPEAEEVPDAAMMERDPSRVWSLFGPLRGPL-
-QAATPNAAHVALAQWQARL-RSFTLVTQNVDGLHTRAG--EVVELHGSLLHTRCVNCGTTPFEDL----IPVCVRCGQ--PLRPDVTLFNEPLD---AA
KRALRECDLFLAVGTSGTVAPASSFVRGAKY-GAWTLLLNLTPQPRHPDFDQEVLGRAEELLPFLLNS-----------
>tr|W6JV73|W6JV73_9MICO NAD-dependent deacetylase OS=Tetrasphaera australiensis Ben110 GN=cobB PE=3 SV=1
------------------------------------AARSPRVVVLTGAGMSAESGLATFRDPAGLWERFSPQALASASAWEDDPELVWAWYLWRFERI-
-EHVAPNAGHVAIARWGRGA--DVSVVTQNVDDLHERAG--DVVHVHGAIASFRCSVCEAPYAEP---I-RPVCRVCGG--LVRPGVVWFGEVLD---RA
VALVSEADLVVVVGTSGIVYPAAGLPAIARS-GAVVIEINPDR-DVSDMVHHTWHETAARALPALVGSFLPA-------
>tr|A0A0D0JPI3|A0A0D0JPI3_9NOCA Contig_36, whole genome shotgun sequence OS=Rhodococcus sp. MEB064 GN=RU01_15940 PE=3 SV=1
------------------------------------VRDATTITVLTGAGMSAQSGVPTFRDATGLWARYDPEELASPDAFTRDPDLVWAWYRRRAQLV-
-AAAEPNAGHRALARWQLDA-TRVDIATQNVDDLHERAG--VLAHVHGTLAAVRCSICEAPYLDP---L-RPSCAVCGS--PVRPGVVWFGEPLA---AV
AASVEAAEVVLVVGTSGVVYPFAGLPAQARS-GAVVVEVNPEE-AVSDMAHHVWRASAADSLPALVAAVTET-------
>tr|R7WI72|R7WI72_9NOCA NAD-dependent deacetylase OS=Rhodococcus rhodnii LMG 5362 GN=Rrhod_3769 PE=3 SV=1
------------------------------------CAAARSITVLTGAGMSAESAVPTFRDATGLWTGIDPMEIATPRAWRRDPDRVWAWYCWRAALV-
-RRARPNAGHDAIARWQGGA--DVTVATQNVDDLHERAG--VAAHVHGSLFAPRCSECGAAAPGAELA--RPRCGVCGG--AVRPGVVWFGEPLA---AA
AAAATTADLVLVVGTSGVVHPFAALPEAARD-GATVVEVNPED-PITAVAHHAVRATSGSALPRLVPELPRP-------
>tr|A0A0F6S825|A0A0F6S825_9NOCA NAD-dependent deacetylase OS=Rhodococcus aetherivorans GN=AAT18_09935 PE=3 SV=1
------------------------------------ARPARRVAVLTGAGMSAESGVPTFRDATGLWEHFDPADLATPEAWDRDPASVWAWYQWRVALV-
-RRVQPNAGHRALARWGRTV--DLSIVTQNVDDLHERAG--VLSHLHGSLFSPRCAECGTPADLPE----RPACGACGG--DVRPGVVWFGEPLG---VA
TASVLTADVVFVVGTSGIVYPAAGLPSLARR-GIPVVEVNPEQ-DLSDRVDEVWRTTAAVGLPQLVAAVAAE-------
>tr|I8T9U6|I8T9U6_9GAMM NAD-dependent deacetylase OS=Hydrocarboniphaga effusa AP103 GN=WQQ_07450 PE=3 SV=1
------------------------------------LRSARRICVFSGAGMSAESGVPTFRDATGLWERFDAERLATPEAFHRDPSLVWGWYEWRRMKM-
-RLAQPHAGHRALAGLERRA-AQLTVITQNVDDLHERAG--NVLHLHGSLEATRCVRCAAPFALPADI--RPRCASCGG--RVRPGVVWFGESLP---PA
HDAAAACDVWITVGTSGLVYPAAELPLVAAR-GATLVQINPLP-PLDAHYDHVLSGTAAQCLPELFAQERDR-------
>sp|Q607X6|NPD_METCA NAD-dependent protein deacylase OS=Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath) GN=cobB PE=3 SV=1
------------------------------------LRDARHIAVFTGAGVSAESGIPTFRDATGFWENYDASTLASPEGFAADPALVWGWYEWRRTRV-
-LRAEPNPAHYAIAALAADC-PRLTLITQNVDDLHERAG--DPIRLHGSLHHPRCSACEAPYRLPPGI--RPRCARCGA--PVRPGVVWLGENLA---AA
RQAAEDCDLMFSIGTSALVWPAAQLPALVAR-GATVVQVNPAE-ALDGHAGYNLRGAAGKVMPLLLQALRRS-------
>tr|D7BCH6|D7BCH6_MEISD Silent information regulator protein Sir2 OS=Meiothermus silvanus (strain ATCC 700542 / DSM 9946 / VI-R2) GN=Mesil_0952 PE=3 SV
------------------------------------LKEAKRVAVLTGAGISAPSGIPTFRDA-GLWKDFRIEDYATPEAYRRDPLKVWEWYAWRYANA-
-MQAQPNRAHRLLAELERQFPG-FLLVTQNVDGLHARAG--HLVELHGSIGRARCEECGARFPLPD----FPVCPKCGG--RGRPDVVWFGELLG---RA
ENAFAKAEVALVVGTSAEIEPAASLGRLASW-GAYLIEINPNQ-PLSRLADCSLRMGAIEGLEALLSPTSLL-------
>tr|A0A0D0PB37|A0A0D0PB37_MEIRU NAD-dependent protein deacylase OS=Meiothermus ruber GN=SY28_01375 PE=3 SV=1
------------------------------------LLAARRVAVLTGAGISQPSGIPTFRDA-GLWQDFDIEEYATPGAYARNPQKVWEWYAWRYRKV-
-MQAEPNRAHNLLVRLEQ---G-FLLVTQNVDGLHARAG--RLVELHGNIARGRCERCGERFPLPD----FPYCPGCKA--RGRPDVVWFGELLG---RA
QQAFAAAEVALVIGTSAEVEPAASLGWLARS-GAYLIEINPNP-PLSSQADCSLRMGAVEGMEALMEGSG---------
>tr|D5HCF6|D5HCF6_SALRM NAD-dependent deacetylase OS=Salinibacter ruber (strain M8) GN=npdA PE=3 SV=1
------------------------------------LVEAGHVAVLTGAGISAESGIPTFRDP-GLWEEFDPQELANVEAFLDNPELVQGWYRHRREVV-
-EDAAPNAGHHALADLEA---S-MAVVTQNVDDLHNRAE--TVIELHGNITDNYCMDCERAVGTAAV---DARCPDCGG--LVRPDVVWFGEMLD---QA
DATTEQADVFLSVGTSAVVYPAARLPVAARE-GAYVAEVNPDT-GVTDDVHETIQGPAGDVLPALVDAVAAR-------
>tr|A0A0E3Z1K6|A0A0E3Z1K6_9GAMM NAD-dependent deacetylase OS=Pseudoxanthomonas suwonensis GN=WQ53_07675 PE=3 SV=1
------------------------------------FAAAARVCVLTGAGMSAESGVPTFRGGDSLWSRFDPRVLATADAWRRDPALVWAWYRWRMHLV-
-GQARPHAGHFALAELGRCH-QALSLVTQNVDDLHERAG--VQAHVHGSLFALRCFDCGQAYDRPLPD--RPACVACGG--GVRPGVVWFGEALA---IA
VGCATGCALMLVVGTSGLVHPAAGLPALARR-GAMVVEINPEP-ALSDTVDHAWRANAADALPRLLALHPAA-------
>tr|A0A0Q8EVX5|A0A0Q8EVX5_9GAMM NAD-dependent deacylase OS=Pseudoxanthomonas sp. Root630 GN=ASD72_07910 PE=4 SV=1
--------------------------------------------MLTGAGMSAESGIPTFRGTDSLWSRFDPMRLATADAWREDPALVWGWYRWRMQGV-
-RDAQPNAGHRALAELARH--VPLSLVTQNVDDLHERAG--VDGHVHGSLFALRCFACGRAHT-ALDD--RMRCTACGD--RIRPGVVWFGEALD---SA
VDAAERCALMLVVGTSGLVYPAAGLPALARR-GATVVEINPEP-ALSAEVDHVWRATAAEALQQLSVLPRSI-------
>tr|A0A0Q8F2S0|A0A0Q8F2S0_9GAMM NAD-dependent deacylase OS=Pseudoxanthomonas sp. Root65 GN=ASD77_05420 PE=4 SV=1
------------------------------------IDEGGKVCVLTGAGMSAESGIPTFRGTDSLWSRFDPMRLATAEAWREDPALVWGWYRWRMQLV-
-RDAQPNAGHRALADLAQR--IPLSLVTQNVDDLHERAG--VDAHVHGSLFALRCFACGRAHDGPLDD--RMRCVTCGD--RIRPGVVWFGEALD---AA
TEAATRCTLMLVVGTSGLVYPAAGLPAVARR-GAIVIEINPEP-ALSADADHVWRATAAVALPLLAR------------
>tr|A0A0K2ZUX3|A0A0K2ZUX3_XANCT Silent information regulator protein Sir2 OS=Xanthomonas translucens pv. phlei GN=XTPLMG730_2523 PE=3 SV=1
------------------------------------IQGARRVLVLTGAGMSAESGVPTFRGQDSLWARFDPQQLATEDAWRADSALVWGWYRWRMAIV-
-AQAQPHAGHHALVRLAGL--KRTTLVTQNVDDLHQRAG--VAAHLHGRLSALRCGDCGQAWHGLLPP--RPACAACGG--AVRPGVVWFGEALA---RA
ERAADAADLVLVIGSSGLVHPAAGLPLRAKE-GAYVVDLNLEP-GLSSRADLYWRDSAAAALPLLLQRWPAC-------
>tr|A0A0J6G3F1|A0A0J6G3F1_9XANT NAD-dependent deacetylase OS=Xanthomonas axonopodis pv. phaseoli GN=ACP93_02010 PE=3 SV=1
------------------------------------IQGARRVLVLTGAGMSAESGVPTFRGQDSLWSRFDPEQLATEDAWRADPALVWGWYRWRMAIV-
-ALAQPHAGHLALAHLAEV--RHTTLVTQNVDDLHQRAG--VAAHVHGRLSALRCSDCGQPWRGLLPP--RPVCAACGG--TVRPGVVWFGEALA---RA
QTAADVADLVLVIGSSGLVYPAASLPLQAKE-GACVVEINPEP-ALSARADLHWRDSAAVALPLLLQQCLVA-------
>tr|A0A0D1N9J9|A0A0D1N9J9_9RHIZ Contig96, whole genome shotgun sequence OS=Mesorhizobium sp. UASWS1009 GN=QV13_01600 PE=4 SV=1
------------------------------------IQDAQRIVVLTGAGMSAESGVPTFRDA-GLWEKYSPEELATPEAMYNRPDLVWSWMLHQARVM-
-RSVEPHDGHRMLGSWQREL-GALNIVTQNIDDLHERGG--VLAHLHGTTFTFRCF-CQAPSDYRL-E--LPACGVCHG--FIRPNIVMFGELLH---DA
LEAVREADVAIVVGTSNIVQPAATLPIAASA-GALVIEINPHM-PLSQDADLYIPGTAGTILPELYP------------
>tr|A0A075TTG7|A0A075TTG7_9CORY NAD-dependent deacetylase OS=Corynebacterium atypicum GN=CATYP_00315 PE=3 SV=1
------------------------------------ADRPLEVEIFTGAGISADSGLSTFRDATGLWSHVDPTALANIDAWERDPEPMWAWYLWRARLS-
-LSAEPNPGHLTVARWQAEG-GHVHVTTQNIDNLHERAG--EVAHLHGSLFSFRCSRCAAPYNG-VDA--RPKCPRCGG--IVRPGVVWFGEALQ---AA
EAAMRRADVVIIIGTSGVVYPAASLPLLAAQ-GAVIIEVTPKP-ELTPVATETLLTTAGIGLPALYQEVAG--------
>tr|W5XPC4|W5XPC4_9CORY NAD-dependent deacetylase OS=Corynebacterium casei LMG S-19264 GN=CCASEI_01030 PE=3 SV=1
------------------------------------IHDASHVHFFTGAGMSADSGLDTFRDATGLWEKVNPQDMASVEAWQRDPEPMWAWYLWRARLA-
-RRAVPHAGHEAIA---KHS--KVTVTTQNIDDLHERAG--EVAHLHGSLFAFRCSSCHTPYSREIEL--RPECEKCSG--LIRPGVVWFGESLD---KA
EEYMSAADAVVIVGTSGSVWPAAGLPTIAHR-KIPIIEVSPQR-DLSDLATVHITNKAVYSLPEILFP-----------
>tr|G0HG52|G0HG52_CORVD NAD-dependent deacetylase OS=Corynebacterium variabile (strain DSM 44702 / JCM 12073 / NCIMB 30131) GN=CVAR_2587 PE=3 SV=1
------------------------------------ARSARRVEVFTGAGMSADSGLDTFRDATGLWSNVDAQAMATLDSWRRDPDPMWAWYLWRAARA-
-RDAAPNPGHLAIARWQDAL-GHLHVTTQNIDDLHERGG--DVSHLHGSLLAFRCSECGRSAPE-PDL--RQACAECGG--PVRPGVVWFGEALK---DA
EASMLSCDLVVIVGTSGVVFPAAGLPELAVR-GVPVVEISPAA-DLTQLSTWSLRTTAASGLPELVDAALA--------
>tr|A0A0F3IBY4|A0A0F3IBY4_9NOCA NAD-dependent deacetylase OS=Rhodococcus sp. PML026 GN=VF34_01662 PE=3 SV=1
------------------------------------ARAASRIVVLTGAGMSAESGIATFRDATGLWQDFDPKDLASPEGWLADSDLVWGWYRWRAALV-
-RRSEPNAGHRAVAQWQQHA--QVDIATQNVDDLHERAG--VLAHVHGSLFEPYCSECGVRAELDDPDLGRPDCPRCGG--LIRPGAVWFGESLQ---AA
ENAVRAADLVLVVGTSGVVYPFAGLPAVARS-GATVVEINPVE-EVSDMADHRWRTTAAVGLPLLVAQL----------
>tr|L8DNL4|L8DNL4_9NOCA NAD-dependent deacetylase OS=Rhodococcus sp. AW25M09 GN=RHODMAR_2836 PE=3 SV=1
------------------------------------ARGASRIVVLTGAGMSAESGIATFRDATGLWKDFDPKDLASPEGWQADSDLVWGWYRWRAELV-
-RRSEPNAGHIALARWQERA--HVDIATQNVDDLHERAG--VLSHVHGSLFEPYCSDCGVRAQLDDAA--RPECPVCGG--LIRPGAVWFGESLD---AA
EDAVRAADLVLVVGTSGVVYPFAGLPAIARS-GATVVEINPVE-EVSDMADYRWRATAAVGLPALVAQL----------
>tr|F1YQ15|F1YQ15_9ACTN Silent information regulator protein Sir2 OS=Gordonia neofelifaecis NRRL B-59395 GN=SCNU_20132 PE=3 SV=1
------------------------------------ITAADHVCVFSGAGMSAESGIPTFRDATGLWENYEPADLATPEGWRRDSDLVWGWYRDRAARL-
-REVEPNAGHYAVAELGRKK-GRVSVITQNVDDLHERAG--VDAHLHGSLKAPRCEACPHHADPDV----EPRCSECGA--SLRPGVVWFGESLL---TA
SHTVGACDLLIIIGTSGVVHPAAGLPMLAAE-GTPIIEVNPEP-ALTPLATVHLPTTAAATLPLIV-------------
>tr|U4TD46|U4TD46_9GAMM NAD-dependent protein deacetylase of SIR2 family OS=Psychrobacter aquaticus CMS 56 GN=M917_0671 PE=3 SV=1
------------------------------------LASKQRICILTGAGISAESGIPTFRDKTGLWQNYRAEDLATPDAFARDPKLVWSWYQWRRKLV-
-ADKTPNPAHDALAQWQQHA-QQLTLITQNVDNLHEQAG--TVIHLHGNLWHNRCSQCEAPYQDKSEGS-DLTCQHCAG--YIRPDIVWFGETLQ---TA
EEAAAHCEVFISIGTSSLVYPAAGLAQLAKQ-GAKIIEINPDP--PNTIVNITLAAKAGVVMPALIKQVMTL-------
>tr|F5SNP7|F5SNP7_9GAMM NAD-dependent deacetylase OS=Psychrobacter sp. 1501(2011) GN=HMPREF9373_0680 PE=3 SV=1
------------------------------------LQNAQHICILTGAGISAESGIPTFRDKTGLWENYRAEDLASIEAFERDPKMVWSWYQWRRNLV-
-KDKRPNPAHHALATLEDWA-KTLSLITQNVDDLHEQAG--QATHLHGHLWKNKCSQCESPYLAEVN---QLHCPQCEA--YIRPDIVWFGEMLK---YA
EQASANCDVFISIGTSSLVYPAAGLSQLAKR-GAKLIEINPNP--QNPIIDVVLAGKAGELLPSLIAELS---------
>tr|I4BBT9|I4BBT9_TURPD NAD-dependent deacetylase OS=Turneriella parva (strain ATCC BAA-1111 / DSM 21527 / NCTC 11395 / H) GN=Turpa_4113 PE=3 SV=1
------------------------------------LRSARAPLFLSGAGISAESGIPTFRGA-GLWNNYRSEDLATPVAFARDPALVWSWYNWRKRLI-
-AEKQPNAAHYAAADISR---T-LLAATQNVDGFHAVAG--NILEMHGNIYRTRCTACGDITENRGDI---TPCATCEP--TLRPDIVWFGEALN---PI
YERLQICDAIVVVGTSGSVYPAAGFAVEVRR-EGHVIEINVDE-HGHYANDIYLRGRAGEILPRIAELL----------
>tr|A5WD15|A5WD15_PSYWF Silent information regulator protein Sir2 OS=Psychrobacter sp. (strain PRwf-1) GN=PsycPRwf_0601 PE=3 SV=1
------------------------------------ISKANRIFLLTGAGISAESGIPTFRDKTGLWENYRAEDLANINAFKKDPQTVWSWYQWRRGLV-
-QDKQPNPAHYALANLQQWA-KDCSLITQNVDDLHEQAG--QAIHLHGHLWKNKCSQCDASFSDAID---DLSCPMCGG--HIRPDIVWFGEMLG---YA
EEAAVHCDVFISIGTSSLVYPAAGLAQLAKQ-GAKVIEINLNP--QSPLVDVVLAGQAGEILPRILAALEDK-------
>tr|A0A0M4T8D9|A0A0M4T8D9_9GAMM NAD-dependent protein deacylase OS=Psychrobacter urativorans GN=AOC03_08725 PE=3 SV=1
------------------------------------LRTAQRICILTGAGVSAESGIPTFRDKTGFWAQYRAEDLASPEGFLREPELVWAWYQWRRELV-
-QDKTPNPAHQALAQWQHNA-QEFTLITQNVDDLHEQAG--TVTHLHGHLWRNRCSQCHAPYVAPLA---GLNCESCGG--YIRPDIVWFGESLD---TA
EAAAANCEVFISIGTSSLVYPAAGLAQLARQ-GATVIEINPNPTQSDTIVDIILAEKAGIVLPILLEQMTSQ-------
>tr|X0RGA3|X0RGA3_9GAMM NAD-dependent protein deacetylase of SIR2 family OS=Psychrobacter sp. JCM 18903 GN=JCM18903_2265 PE=3 SV=1
------------------------------------LTSKQHICILTGAGISAESGIPTFRDKTGLWENYGVEDLATPEAFTRDPKLVWSWYQWRRQLV-
-ADKKPNPAHFALAQWQYHT-QSLTLITQNVDDLHEQAG--TVTHLHGNLWHNRCSQCETACQSQSRGY-DMTCPHCGG--YIRPDIVWFGEALQ---TA
EDAAANCEVFISIGTSSLVYPAAGLAQLAKQ-GAKIIEINPNP--PNTIVDITLAEKAGVIMPLLIQKITAL-------
>tr|A0A0R0A3C8|A0A0R0A3C8_9GAMM NAD-dependent protein deacylase OS=Psychrobacter sp. P11G3 GN=AK824_02565 PE=4 SV=1
------------------------------------LASKQRICILTGAGISAESGIPTFRDKTGLWENYGVEDLVTPEAFTRDPKLVWSWYQWRRQMV-
-ADKAPNPAHHALAQWQYHA-QQVTLITQNVDDLHEHAG--AVTHLHGHLWRNRCSQCEIPYQDQSRAY-DLSCPHCDG--YIRPDIVWFGEALQ---TA
EDAAANCEVFISIGTSSLVYPAAGLSQLAKQ-GAQVIEINPDP--PNTIVDITLVEKAGIVLPLLIAEITTL-------
>tr|S4Z0J1|S4Z0J1_9GAMM Sigma factor regulator FecR OS=Psychrobacter sp. G GN=PSYCG_02560 PE=3 SV=1
------------------------------------LESKQHICLLTGAGISAESGIPTFRDKTGLWENYRAEDLATPDAFARDPKLVWSWYQWRRQLV-
-ASKKPNPAHTALAQWQYHS-QQLTLITQNVDDLHEQAG--AVTHLHGNLWRNRCNQCQTPYTIQLKGY-DVTCQHCDG--YIRPDIVWFGESLH---TA
EEAAASCDVFISIGTSSLVYPAAGLAQLAKH-GAKIIEINPYP--PNTLVDITLAAKAGVILPELVKRMGVL-------
>tr|A4WM89|A4WM89_PYRAR Silent information regulator protein Sir2 OS=Pyrobaculum arsenaticum (strain DSM 13514 / JCM 11321) GN=Pars_1959 PE=3 SV=1
------------------------------------LAASRHCIVFTGAGISAESGVPTFRGL-GLWERYRPEELATPEAFARDPELVWRWYKWRQEVV-
-YNARPNPGHMAIAELEA---VVKAVVTQNVDGLHQRAG--RVVELHGSLWRTRCTKCGA-------VY-DPRCGKCGG--LLRPDVVWFGEPLD---EA
VELARISDVVLVVGTSGVVYPAAYIPHIAKQ-GAVVIEINVEP-ALTPMADYFIRGRAGEVLPQIAEEVKKR-------
>tr|H5S9R5|H5S9R5_9ZZZZ Silent information regulator protein Sir2 OS=uncultured prokaryote GN=HGMM_F03G07C25 PE=3 SV=1
------------------------------------MSSGPRVVALTGAGISAESGVPTFRGP-GLWGRYRPEELATPEAFTRDPTRVWEWYAWRRERI-
-ARAEPNPAHRTLAEMEA---G-FRLITQNVDGLHQRAG--RVIELHGNIWRVRCVREGRTWEDD-----PPRCPACGA--WLRPDVVWFGEPLA---QA
LEAAQQAEIFLVIGTSGMVEPAASLPRLARA-GAWIIEFNLEE-PLTPLADEVWRGPVGETLPHWWRAFQDR-------
>tr|G2LGP9|G2LGP9_CHLTF NAD-dependent protein deacetylase, SIR2 family OS=Chloracidobacterium thermophilum (strain B) GN=Cabther_A0399 PE=4 SV=1
------------------------------------LAAARRVVVFTGAGISAESGVPTFRGK-ATWKGMPAAVASSIGLLEQDLTTAWEWFDYRRTLL-
-KTVVPNPAHIAVAQAET---D-FLVVTQNVDGLHQKAG--RIIELHGNIWRGRGLRTGKRYPLPE----PPR-GDHDE--PLRPDVVLFGEMLG---EA
EIAASRCDVCLVIGTSGVVYPAALIPFAARD-GAAVIEVNPES-DLTPHMTLSLRGRAGDIVPRLFG------------
>tr|F2L293|F2L293_THEU7 NAD-dependent deacetylase OS=Thermoproteus uzoniensis (strain 768-20) GN=TUZN_1552 PE=3 SV=1
------------------------------------LANSRFAVAFTGAGISAESGVPTFRGP-GLWERYRPEDLATPEAFWKDPVLVWRWYRWRQELI-
-YNAAPNPAHLALAELES---VLKAVITQNVDGLHKRAG--RVVELHGNIWRARCTSCGR-------EL-DPRCPHCGG--LLRPAVVWFGEPLD---EA
LLLASSADFMLVVGTSGVVYPAAYIPRIAKR-GAVVAVVDPGE-ALDDIADFKIRGRAAEILPRLAAEVRRC-------
>tr|U3TEX8|U3TEX8_9CREN NAD-dependent deacetylase OS=Aeropyrum camini SY1 = JCM 12091 GN=npdA PE=3 SV=1
-------------------------------------REAGSAVAFTGAGISAESGIPTFRGK-GLWSRFDPRELATPEAFSRSPRLVWEWYAWRIERV-
-LSAKPNKAHRLLARLED---L-TAVITQNVDGLHRRAG--RVLELHGNILRARCTSCGLKLEWGGK---EPTCPECGG--LLRPDVVWFSEPLG---EA
FRLARQCDVMIVIGTSGAVDPAGLIPLVAKD-GAVLVNVNPEP-RYTGMADVELRMKAVQFAERVSAALGIN-------
>sp|O28597|NPD1_ARCFU NAD-dependent protein deacylase 1 OS=Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126) GN=
-------------------------------------AESKYLVALTGAGVSAESGIPTFRGK-GLWNRYRPEELANPQAFAKDPEKVWKWYAWRMEKV-
-FNAQPNKAHQAFAELER---L-KCLITQNVDDLHERAG--NVIHLHGSLRVVRCTSCNNSFEVESA---IPKCDKCGS--LLRPGVVWFGEMLD---RA
MREVERADVIIVAGTSAVVQPAASLPLIVKQ-GGAIIEINPDE-PLTPIADYSLRGKAGEVMDELVRHVRKA-------
>tr|L0HLR7|L0HLR7_ACIS0 NAD-dependent protein deacetylase, SIR2 family OS=Aciduliprofundum sp. (strain MAR08-339) GN=AciM339_0847 PE=3 SV=1
------------------------------------LLDAKKIVALTGAGISAESGIPTFRGS-GLWEGYPVEKVATVEGFERDPELVWRFYDEMRINI-
-ARAEPNEAHMVLAKMEN-----LWVITQNIDGLHTRAG--NVIELHGNIWRTKCTECGRVDYNY-----RPKCGKCGG--LLRPDVVWFGEPV----KA
YKLSEECDVMFVIGTSAQVYPAAYLPRVAWS-GAKIVEINLEK-PVSRYADFVIRKPATVAMREIYQGLLGA-------
>tr|A3MXL2|A3MXL2_PYRCJ Silent information regulator protein Sir2 OS=Pyrobaculum calidifontis (strain JCM 11548 / VA1) GN=Pcal_1963 PE=3 SV=1
------------------------------------IAKSRHCVVFTGAGMSAESGVPTFRGS-GLWERYRPEELATPEAFARDPVLVWKWYKWRQEIV-
-YNARPNPGHYAIAKLEE---VVKAVVTQNVDGLHQRAG--RVVELHGSLWRARCTKCGA-------VY-EPRCPRCSS--LLRPDVVWFGEPLE---EA
VRLMAASDVVIVVGTSGVVYPAAYLPKLAKE-GAAVVEINVEE-AITPIADVFIRGKAGEVLPRLAEEVLKR-------
>tr|G4RLW2|G4RLW2_THETK Transcriptional regulatory protein, Sir2 homolog OS=Thermoproteus tenax (strain ATCC 35583 / NBRC 100435 / JCM 9277 / Kra 1) GN
------------------------------------LARSSYAVAFTGAGVSADSGIPTFRGP-GLWSRYRPEELATPEAFLRDPLLVWEWYKWRQELI-
-YRAAPNPAHIALAKLEK---IIKSIITQNVDGLHERAG--TVVELHGNIWRLRCIRCGA-------TM-DPRCPRCGG--LMRPDVVWFGERLG---KA
VDHASRADIMLVVGTSGAVFPAAYLPRLAKD-GAKIAVIDPGD-AFDDIADFRVRERAGEALPKLVEYVEAI-------
>tr|A0A0K1E182|A0A0K1E182_9CREN NAD-dependent protein deacetylase, SIR2 family OS=Pyrobaculum sp. WP30 GN=PYWP30_00969 PE=3 SV=1
------------------------------------VAAARHCIVFTGAGISAESGVPTFRGA-GLWERYRPEELATPEAFARDPELVWRWYRWRQELV-
-YRAGPNPGHRAVAELEA---VVKAVITQNVDGLHQRAG--NVVELHGSLWRARCVECGA-------VY-EPRCPRCGG--LLRPDVVWFGEPLD---RA
VELASRSDVVLVVGTSGVVYPAAYIPRIAKD-GAVLVEVNVEE-AITPIADFFLRGRSGEVLPRLVEEVKKG-------
>tr|C7FPF3|C7FPF3_9BACT NAD-dependent protein deacetylase OS=uncultured bacterium HF186_25m_18N5 PE=3 SV=1
------------------------------------LRRAERVFVVSGAGISAESGIPTFRGS-GLWEGFRAEELATPQAFAADPERVWRWYRWRAEQY-
-GDCAPNAGHDTIAAMAS---R-LLVATQNVDGLHRRAG--AVVELHGSIADMRCTACDTLAPFPR----SPRCALCGE--RMRPHILWFGETYG---RA
QQAAEEADVCLVVGTSAQVWPPVALALHAQA-GAFLIDINPEA-ELSGRADAHLAGPSGRLLPELWERVGR--------
>tr|A0A0F2LA47|A0A0F2LA47_9CREN NAD-dependent protein deacylase OS=Thermoproteus sp. AZ2 GN=TU35_00500 PE=3 SV=1
------------------------------------LAESSFAVALTGAGVSAESGVPTFRGP-GLWERYRPEDLATPEAFAKDPVLVWRWYRWRQEVI-
-RAASPNPAHIALARLEE---VLKAVITQNVDGLHQRAG--RVVELHGNIWRVRCVSCGL-------VE-SPRCKRCGG--LMRPDVVWFGEPLK---EA
LAYAGSADVMLVVGTSALVHPAALLPRVAKS-GAVLININPAE-PLDEMADFNIRGRAGEVLPKLAQAVEAW-------
>sp|Q8ZT00|NPD2_PYRAE NAD-dependent protein deacylase 2 OS=Pyrobaculum aerophilum (strain ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827) GN=co
------------------------------------LASSRHCVVFTGAGISAESGVPTFRGP-GLWERYKPEELATPEAFARDPALVWRWYKWRQEVI-
-YNARPSPGHYAIAELEA---VVRGVITQNVDGLHQRAG--LVVELHGSIWRARCVKCGS-------VY-EPLCRKCGG--LLRPDVVWFGEPLE---AA
VELASVSDVLLVVGTSGVVYPAAYIPRIAKE-GARVVEINVEP-AITPIADVFIQGRAGEVLPRLVEEVKRR-------
>tr|A0A062XVY7|A0A062XVY7_9BACT NAD-dependent protein deacylase OS=Thermoanaerobaculum aquaticum GN=EG19_04985 PE=3 SV=1
------------------------------------LSRAKNVVVFTGAGVSAESGLATFRGA-GLWEGHRVEDVATPEAFGRDPLLVWRFYAMRRENA-
-KKAQPNPAHKAIAKLEE---S-LVVVTQNVDGLHQRAG--RVLELHGSLWRLFCAKCGRTREDH-----PPRCGVCGG--LERPGVVWFGEPLA---EA
ERVSSQADAMLVVGTSGVVWPAAGLVEVAAA-GAAVIEVNPEP-ALAYLATVQIPAKAGEALPALTARLLEV-------
>sp|Q8TWG0|NPD_METKA NAD-dependent protein deacylase OS=Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938) GN=cobB PE=3 SV=1
------------------------------------VVEAETVVVLTGAGASADSGIPTFRGK-GLWNKYDPRELATPEAFARDPEKVWEWYLWRRRKI-
-AEAEPNPAHTVLARMER---L-EAVITQNVDGLHQRAG--RVIELHGNIWRDECVSCEYQRVNDPER--DPRCPECGD--PLRPGVVWFGEPLD---EA
ENLARSCDVMLVIGTSGEVRPAADLPLVAKS-GATLIEINPSE-ALSPHMDVIIRERAASAMEALWNEIERL-------
>tr|B1L5P3|B1L5P3_KORCO NAD-dependent protein deacetylase, SIR2 family OS=Korarchaeum cryptofilum (strain OPF8) GN=Kcr_1026 PE=3 SV=1
------------------------------------RRNSGKVVAFTGAGISAEAGIPTFRGK-GLWEKYDPEELATPQAFFRDPKLVWDWYLWRMSII-
-ARARPTPAHEILALWED---L-KGVITQNVDGLHQRAG--NLVELHGSIWRIRCTSCDNKVYLG-----EPECDRCGS--IMRPDVVWFYEPLD---RA
EDMIRSASLLLIIGTSGLVMPAATLPMMALR-NATLVEINPEE-NLSSLAKFRVREGASRIFVDLNEMLEGI-------
>tr|A1RSN7|A1RSN7_PYRIL Silent information regulator protein Sir2 OS=Pyrobaculum islandicum (strain DSM 4184 / JCM 9189 / GEO3) GN=Pisl_0793 PE=3 SV=1
-------------------------------------HKSAFCIAFTGAGISAESGVPTFRGA-GLWERYKPEELATPEAFERNPELVWRWYRWRQELV-
-YNAKPNPGHLALAELEN---I-KAIITQNVDGLHQRAG--NVVELHGSLWRARCVKCGLTYRLERP---EPRCPNCGG--LLRPDVVWFGEPLD---KA
VELAHKSDVVLVIGTSGVVYPAAYIPHIAKR-GALVIEINTEE-AITPIADIFIKGRAGVVLPALVREIRRR-------
>tr|B1YDE6|B1YDE6_PYRNV Silent information regulator protein Sir2 OS=Pyrobaculum neutrophilum (strain DSM 2338 / JCM 9278 / V24Sta) GN=Tneu_0872 PE=3 S
------------------------------------LLRARFCVVFTGAGVSAESGIPTFRGA-GLWERYRAEDLATPEAFARDPKLVWEWYRWRQTLA-
-YNARPNPAHYAIAQLEE---LVKAVITQNVDGLHQRAG--RVVELHGSLWRARCVQCGA-------VY-EPRCPRCRG--LLRPDVVWFGEPLE---EA
VQLASSADVVLVVGTSGAVYPAAAIPQIAKR-GAAVVEVNVEK-ALTAIADVFIRGKAGEVLPALVEEVRRG-------
>tr|A2BMS1|A2BMS1_HYPBU NAD-dependent protein deacetylases, SIR2 family OS=Hyperthermus butylicus (strain DSM 5456 / JCM 9403 / PLM1-5) GN=Hbut_1458 PE
-------------------------------------VQYRPFIAFTGAGISAESGVPTFRGR-GLWERFRPEELATPEAFERNPRLVWEWYRWRMEII-
-YKARPNPAHYALVELER---I-RCVVTQNVDGLHQRAG--CVVELHGNIWRARCMRCSYKLVFREP---RPRCPRCGG--LLRPDVVWFGEPLE---TA
VELAESSQGILVVGTSGVVMPAGYIPHIVKQ-GGYVVEVNIEE-AVTPIADVFLKGRAGEVLPRLVEEARKL-------
>tr|A0A0K9I3Y9|A0A0K9I3Y9_9DELT NAD-dependent protein deacylase OS=Desulfocarbo indianensis GN=AAU61_19245 PE=3 SV=1
------------------------------------LAAAQRVTVLTGAGVSAESGVPTFRGA-GLWENHRPEDLATPQAFARDPALVWRWYQWRRGLI-
-AQCRPNPAHVALAGLER---R-CTLITQNVDGLHRQAG--DPLEIHGDIWRLRCLGCGRVWLSRDLG--PPACPQCGG--LARPDVVWFGEALA---KA
WQAARLADYMLVAGTSALVQPAAGLAAVAKE-GAFVVEVNLEP-PNSAWVDVSLFGKAGDILPRLLEAL----------
>tr|M3VDM8|M3VDM8_9ACTN NAD-dependent deacetylase OS=Gordonia paraffinivorans NBRC 108238 GN=cobB PE=3 SV=1
------------------------------------VRDADWITVFSGAGMSADSGIATFRDATGLWETFDPSELATPEAWERDPALVWGWYRWRAREV-
-LSAEPNAGHRALAELGS---RTVMVVTQNVDDLHERAG--VVSHLHGSLFAPRCADCGTPYDGPE-AP-RPTCPRCGG--RVRPGVVWFGEALD---RA
DQAFRAAEVVLVVGTSGIVYPAASLPERAAR-GIPVIEFNPAE-AVTSIATHSLRVSAAVGLPALLRAIG---------
>tr|L7L261|L7L261_9ACTN NAD-dependent deacetylase OS=Gordonia amicalis NBRC 100051 = JCM 11271 GN=cobB PE=3 SV=1
------------------------------------VRGAEWITVFSGAGMSAESGIATFRDATGLWETFDPAELATPEAWERDPALVWGWYRWRAREV-
-LAAEPNAGHRALAELGA---RTVMVVTQNVDDLHERAG--VVSHLHGSLFAPRCSVCHTPYDGPD-AP-RPTCPRCGG--DVRPGVVWFGEALD---RA
DQAFRAGEVVIVVGTSGIVYPAASLPERAVR-GIPVIEFNPAE-SVSELVTHSLRVPAAEGLPALLRALD---------
>tr|A0A022LMN1|A0A022LMN1_9ACTN NAD-dependent deacetylase OS=Dietzia sp. UCD-THP GN=H483_0108295 PE=3 SV=1
------------------------------------LAGGGPLVVLTGAGMSAESGVPTFRDATGLWAHHDPAALATPEAWDRDPEAVWAWYRWREHLV-
-GSAEPNAGHLAITRAAGER--RVTVVTQNVDDLHERAG--DVHHLHGSLFAHRCDVCGTAIEVG-----RPSCSRCGG--RARPGVVWFGEMLQ---AA
VSAISTASAVLVVGTSGLVHPAASLPGLAAD-GVPLVEVNPGP-GFPHQATVHLRATAGQALPSLLAP-----------
>tr|A0A0K2YEG6|A0A0K2YEG6_9NOCA NAD-dependent protein deacylase OS=Rhodococcus sp. RD6.2 GN=cobB PE=3 SV=1
------------------------------------VRSVERVTVFSGAGMSAESGVPTFRDATGLWERFDPTELATPQAWEKDPALVWAWYEWRAALV-
-RRVQPNAGHRAVAEWADTA--EVTVLTQNVDDLHERAG--VAAHLHGSLYAPRCCLCGLAADLDDARA-RPSCESCTA--PVRPGAVWFGEELD---AS
VDAVEHCDLMLVVGTSAVVYPAAELPLRALR-GATVVEINPEP-DLSSAVTHSWRATAAQALPVLAAVGQGR-------
>tr|D0LAD2|D0LAD2_GORB4 Silent information regulator protein Sir2 OS=Gordonia bronchialis (strain ATCC 25592 / DSM 43247 / JCM 3198 / NCTC 10667) GN=Gb
------------------------------------IQDAEWVTVFTGAGMSAESGIATFRDATGLWENFDPTDLATPEAWDRDPALVWGWYSWRARQV-
-RAARPNAGHLALVDLAG---RTVMVVTQNVDDLHERAG--VISHLHGSLFAPRCAVCGRPYAPGPSLE-RPSCSFCGG--LVRPGIVWFGEALQ---RA
EQAFRGSDVVLVVGTSGIVYPAAGLPERAAR-GIPVIEVNPEP-ALSPIARHRIAMTAATGLPGLVRRLS---------
>tr|M7A2B2|M7A2B2_9ACTN NAD-dependent deacetylase OS=Gordonia sp. NB4-1Y GN=ISGA_2151 PE=3 SV=1
------------------------------------VADAGWITVFSGAGMSADSGVPTFRDATGLWENFDPATIASPEAWDADPALVWGWYHWRAHLV-
-RDARPNAGHLALAELSSV--RALMVVTQNVDDLHERAG--VLSHLHGSLFAPRCSVCDTPYDGPDAD--RPTCAVCGG--AVRPGIVWFGEHLD---RA
ENAFRGADVVLVVGTSGIVYPAASLPERAAA-GVPVIEINPEP-ALTEVATHSIRAGAATALPALVDAIRRR-------
>tr|H5UAN6|H5UAN6_9ACTN NAD-dependent deacetylase OS=Gordonia terrae NBRC 100016 GN=cobB PE=3 SV=1
------------------------------------VRRAEWITVFSGAGMSAESGIATFRDATGLWEKFDPAELATPEAWARDPALVWGWYRWRAREV-
-LAAQPNAGHLALAELAT---RTVMVVTQNVDDLHERAG--VVSHLHGSLFAPRCSVCGTPYDGPG-AP-RPTCPRCGG--VVRPGIVWFGEALS---RA
DQAFRAAEVVLVVGTSGIVYPAAALPERAVR-GIPVIEFNPAP-ALSDVVTHSLRMPAAVGLPALLRSVR---------
>tr|C8RVL8|C8RVL8_CORJE Transcriptional regulator, Sir2 family OS=Corynebacterium jeikeium ATCC 43734 GN=HMPREF0297_2070 PE=3 SV=1
------------------------------------VRRAKYVEVFTGAGMSADSGLDTFRDATGIWSHVDPQAMATLDSWAKDPESMLAWYLWRAVLC-
-RRAEANAGHRAIGEWAARG-VTVHVTTQNIDDLHERGG--NVAHLHGSLFRYRCSICSKPARM-PEL--RPTCSLCGN--PVRPGVVWFGEPLR---AA
EEAMRAADLVVIIGTSGVVWPAAGLPAIAAR-GTPIVEISPAR-DLTDMCTWSLRTTAANGAPLLVEAAEGA-------
>tr|W5WNB4|W5WNB4_9CORY NAD-dependent deacetylase OS=Corynebacterium falsenii DSM 44353 GN=CFAL_00425 PE=3 SV=1
------------------------------------IRAARCVNFFTGAGMSADSGLDTFRDATGIWSHVDPQAMASLSSWARDPDPMLAWYLWRGTLC-
-RRAEPNPGHRAIGEWSRRD-VEVNVTTQNIDDLHERGG--NIAHLHGSLFAYRCSICGKPAAT-PEL--RPACSLCGN--PVRPGVVWFGESLK---RA
ERWMREADLVVIVGTSGVVWPAAGLPAIAAR-GTPIVEISPAD-DLTDLATWSIRATAAEGVPALLAALDDQ-------
>tr|B1VE51|B1VE51_CORU7 Uncharacterized protein OS=Corynebacterium urealyticum (strain ATCC 43042 / DSM 7109) GN=cu0080 PE=3 SV=1
------------------------------------LTGARNVVVFTGAGMSKDSGLDTFRDATGIWERINPQDMASLGSWAKDPDPMYAWYLWRGHVC-
-QQAAPNAGHVAIAEWENSS-INLHVVTQNVDDLHERAG--RISHLHGSLFSYRCAICHKPART-PEF--RPNCSLCGN--PVRPGVVWFGEPLR---AS
EAAMREADLVVIIGTSGVVYPAAGLPQVAKA-GARILEISPER-DLTRLADWSLRATAAEGAPAIVAAARG--------
>tr|F0LIW7|F0LIW7_THEBM NAD-dependent protein deacetylase of SIR2 family OS=Thermococcus barophilus (strain DSM 11836 / MP) GN=TERMP_00336 PE=3 SV=1
-------------------------------------ARSRFLIAFTGAGISAESGIPTFRGR-GLWKRHRPEELATPEAFARNPKLVWEFYRWRMKII-
-SKAKPNKAHLVLAELER---L-KAVITQNVDDLHREAG--NIIELHGNIFRVKCIRCDYRENLKESGL-DPKCPKCGS--LLRPDVVWFGEALS---KA
FSLARRADVCLVVGTSGQVFPAAYIPYIVKD-GGYVIEINPSQ-GITPIADIFIRGKAGEVMDELLKKVEEL-------
>tr|E6VWR1|E6VWR1_DESAO Silent information regulator protein Sir2 OS=Desulfovibrio aespoeensis (strain ATCC 700646 / DSM 10631 / Aspo-2) GN=Daes_2677 P
------------------------------------LDPGRRVVVLTGAGVSAESGVPTFRGR-GLWKTHRAEDLARPDAFAARPGLVWEFYHWRRGLV-
-AGCEPGPAHHALAALER---N-FLLITQNVDGLHARAG--KLVEMHGSLWQVRCTACTHVREDH-GD--PPECPACGH--LLRPGVVWFGEPLG---LA
VEELHRADVFLAIGTSGLVQPAASFHQLARE-GAVTVEINVEA-PVTGLMDFALHGRAGDILPELVAGMAG--------
>tr|F0JKK3|F0JKK3_DESDE Silent information regulator protein Sir2 OS=Desulfovibrio desulfuricans ND132 GN=DND132_3249 PE=3 SV=1
------------------------------------LGGDRRVVVLTGAGVSAESGVPTFRGR-GLWKHHRAEDLARPDAFAAHPELVWEFYNWRRRLV-
-GNCYPNAAHLALAAMER---N-FLLITQNVDGLHARAG--KVLEMHGSLWQLCCTVCSHAREDF-SE--PPDCPVCGH--LLRPGVVWFGEPLG---LA
IEAVAKADVFLSVGTSNLVQPAASFYQLAKD-GAVTVEVNMEP-PNTGFMDFALHGPAGDILPELAGGLAG--------
>sp|O58669|NPD_PYRHO NAD-dependent protein deacylase OS=Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) GN=co
-------------------------------------ASSKNVIAFTGAGISAESGIPTFRGK-GLWKKYRPEELATPEAFERNPKLVWDFYKWRIKKI-
-LKAKPNPAHYALVELEK---L-KAVITQNVDDLHREAG--NLIELHGNIFRVRCTSCEFREHLKESGI--PKCPKCGS--LLRPDVVWFGEPLK---EA
FKLAKEADVVIVVGTSGLVYPAAYIPYIVKD-GGVVIEINVQK-GITPIADFFLRGKAGEILPKLVQEVRRI-------
>sp|Q8U1Q1|NPD_PYRFU NAD-dependent protein deacylase OS=Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) GN=cobB PE=3 SV=2
-------------------------------------AKSSMAIAFTGAGISAESGIPTFRGK-GLWRKYRAEELATPEAFKRDPKLVWEFYKWRIKKI-
-LEAKPNPAHIALAELEK---I-KAVITQNVDDLHREAG--NVIELHGNIFRVKCTSCSYREYLKESDI--PRCPKCGS--LLRPDVVWFGEALK---TA
FSLAKKADVVLVVGTSGVVYPAAYIPYIVKE-GGIVVEINIEP-AITPIADFFLRGKAGEVLPKLVEEIRRI-------
>sp|Q9UZE7|NPD_PYRAB NAD-dependent protein deacylase OS=Pyrococcus abyssi (strain GE5 / Orsay) GN=cobB PE=3 SV=1
-------------------------------------ASSKNAIAFTGAGISAESGVPTFRGK-GLWNKYRPEELATPEAFARNPKLVWEFYKWRINKI-
-LKAKPNPAHYALVELED---L-RAVITQNVDDLHREAG--NLIELHGNIFRVKCTKCNFKEYLKESQL--PKCPRCGS--LLRPDVVWFGEPLE---RA
FKLAEKADAVLVVGTSGLVYPAAYIPYIVKE-GGTVIEVNVEE-AITPIADFFLRGRAGEVLPRVVHEVRRL-------
>tr|F8AIU2|F8AIU2_PYRYC NAD-dependent deacetylase OS=Pyrococcus yayanosii (strain CH1 / JCM 16557) GN=PYCH_06390 PE=3 SV=1
-------------------------------------ARSKFAIAFTGAGISAESGVPTFRGK-GLWMRYRPEELATPEAFSRNPRLVWDFYKWRMKLI-
-AKARPNRAHYALAKLEE---L-KAVITQNVDDLHREAG--NLIELHGNIFRVRCTSCDYRENLKESCL--PKCPNCGS--LLRPDVVWFGEPLE---EA
FKLARRADLILVIGTSGLVYPAAYIPYIVKE-GGIVIEINVEE-ALTPIADIFLRGKAGEVMGTLLEEVKKI-------
>tr|F4HK56|F4HK56_PYRSN NAD-dependent deacetylase OS=Pyrococcus sp. (strain NA2) GN=PNA2_1629 PE=3 SV=1
-------------------------------------VSAKFAIAFTGAGISAESGIPTFRGK-GLWNRYRPEELATPEAFKRNPKLVWEFYKWRIKKI-
-LEARPNPAHMALAELEK---I-KAVITQNVDDLHREAG--NLIELHGNIFRVRCTKCDFKEYVKGKRL--PKCPNCGS--LLRPDVVWFGEPLK---EA
FRLAEKSDVIIVIGTSGLVYPAAYVPYIVKE-GGTVVEVNIEN-AITPIADFFLKGKAGEVLPKIAQEIRRL-------
>tr|W0I179|W0I179_9EURY NAD-dependent protein deacetylase of SIR2 family OS=Thermococcus paralvinellae GN=TES1_0407 PE=3 SV=1
-------------------------------------ARSKFLIAFTGAGISAESGVPTFRGK-GLWKQYRPEELATPEAFAKNPKLVWEFYKWRMRLI-
-SKAKPNKAHLALAELER---L-KAVITQNVDDLHREAG--NIIELHGNIFRVKCTHCDYRENLKESGL-DPKCPKCGS--LLRPDVVWFGEALE---RA
FNLARKSDVCLVIGTSGQVFPAAYIPYIVKD-SGYVIEINPNE-GITPIADIFIRGKAGEAMDELLKKIMEL-------
>tr|A0A075LRT9|A0A075LRT9_9EURY NAD-dependent protein deacylase OS=Palaeococcus pacificus DY20341 GN=PAP_03120 PE=3 SV=1
-------------------------------------AHSRFLIAFTGAGISAESGIPTFRGN-GLWENYKVEEVATPEAFKRNPKLVWEFYKMRMRKM-
-RKAKPNKAHIALAELEN---L-KGVITQNIDDLHREAG--NVIELHGNIYRVKCTSCDYKENLKESGL-EPKCPKCGS--LLRPDVVWFGEPLT---NA
FNLARRVDICLVIGTSGQVFPAAYIPYIVKD-KGSIIEINPHE-GITPIADIFLRGRAGEVMEELLRKIWEC-------
>sp|C6A243|NPD_THESM NAD-dependent protein deacylase OS=Thermococcus sibiricus (strain MM 739 / DSM 12597) GN=cobB PE=3 SV=1
-------------------------------------AHSRFLIAFTGAGVSAESGIPTFRDR-GLWENYRIEEVATPEAFRKDPNLVWSFYKMRMKIM-
-KGAKPNNAHLALAELEK---L-KAVITQNIDNLHREAG--HIVELHGNIYRVKCTRCDYMENLLESGL-EPKCPECAS--LLRPDVVWFGEPLE---KA
FKLAERADVCLVVGTSAQVFPAAYVPYIVKD-GGSVIEINTKE-GITPIADVFIRGKAGEVMQSLLVKVKRC-------
>tr|H3ZPS5|H3ZPS5_THELN NAD-dependent protein deacylase OS=Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C) GN=OCC_04655 PE=3 SV
-------------------------------------AHSRFLIAFTGAGISAESGIPTFRDK-GLWEKYRVEEVATPEAFRRNPRLVWEFYKMRMRLM-
-KEAKPNRAHLALAELEK---L-KAVITQNIDNLHREAG--NVVELHGNIYRVKCTSCAYRENLLDSGL-EPKCPECGS--LLRPDVVWFGEPLE---KA
FKLAERADVCLVIGTSGQVFPAAYVPYIVKE-GGYVIEINPRE-GITPIADIFLKGFAGETMEHLLAKVKRC-------
>tr|A0A0P8ZYY8|A0A0P8ZYY8_9EURY NAD-dependent protein deacylase OS=Thermococcus sp. EP1 GN=EP1X_06500 PE=4 SV=1
-------------------------------------THSRFLIAFTGAGISAESGVPTFRDK-GLWEKYKIEDVATPEAFKRNPGLVWEFYKMRMQLM-
-KNARPNSAHLALTELEN---L-KAVITQNIDNLHKMAG--TVIELHGNIYSVKCSNCEYKENLLETRL-EPKCPKCRS--FIRPDVVWFGESLG---KA
FKLAERADVCLVIGTSGQVFPAAYIPYIVKD-GGYVIEINPKE-GITPIADLFLKGNAGEIMKLLLGKVKIC-------
>sp|Q5JG47|NPD_THEKO NAD-dependent protein deacylase OS=Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) GN=cobB PE=3 SV=1
-------------------------------------ARARFAIAFTGAGISAESGIPTFRGR-GLWKTYRAEELATPEAFKRDPHLVWEFYKWRMRKI-
-LKAEPNPAHKALAELEN---L-KAVITQNVDDLHREAG--KVVELHGNIFRVRCVSCSYRENLKESGV-EPKCPKCGS--LLRPDVVWFGEPLE---EA
FSLAERADVVLVVGTSGVVYPAAYVPYIVKE-GGKVIEVNVER-GITPIADVFIRGKAGEVMPELLRRVKDI-------
>tr|I4JMJ0|I4JMJ0_PSEST Cobalamin biosynthetic protein OS=Pseudomonas stutzeri TS44 GN=YO5_15255 PE=3 SV=1
------------------------------------LRDARHALVFTGAGVSAESGIATFRDTSGLWERYDPATLATAHAFRQDPTLVWGWYEWRRMQV-
-LQAQPNPAHLAIAALAQRV-PKLTLVTQNVDDLHERAG--EVIHLHGSLHQPRCFACARAPSQPLGL--HPRCEHCGG--RLRPGVVWFGESLA---AA
FAAADDCDVLISVGTSGVVHPAAQIPERAWR-GAVLAHVNPQP-GSHAEREFLLRGTAAQLMPQLLQAAFGD-------
>tr|A0A0F9TVM7|A0A0F9TVM7_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_0300010 PE=3 SV=1
------------------------------------LCAAQRVVVFSGAGVSAESGIATFRDSIGLWQNFDPARLATVAAFEQDPELVWGWYEWRRMQV-
-LAAQPNAAHLAIAALANTN-LELTVITQNVDDLHERAG--QVLHLHGSLHQPRCHACGEHRLPPEA---RPICAHCAG--MVRPGVVWFGEALH---QA
FETAADCDLLLSVGTSGVVYPAAQVPEIALR-GAAVIHINPQR-LLGIGREWALAGPAAEWMPRLVKTLLSR-------
>tr|J2X309|J2X309_9PSED NAD-dependent protein deacetylase, SIR2 family OS=Pseudomonas sp. GM78 GN=PMI35_05833 PE=3 SV=1
------------------------------------LQNAKHVLVFTGAGVSAESGIPTFRDAVGLWARFDPAALATREAFRRDPTFVWGWYEWRRMQV-
-YNAQPNLAHRAIAELSAMV-PKLTLVTQNVDDLHERAG--GVIHLHGSLNKPRCFACARFAIDPMPP--HPRCSHCGG--KLRPGVVWFGESLQ---QA
FAAAKDCDVLLSVGTSGVVEPAAQIPDIAWR-GATVVHINPDA-CVRSAREFWLGGRASEVLPQLLMQGFRP-------
>tr|F0S0Y4|F0S0Y4_DESTD NAD-dependent deacetylase OS=Desulfurobacterium thermolithotrophum (strain DSM 11699 / BSA) GN=Dester_0130 PE=3 SV=1
------------------------------------LKSFQSVAVLTGAGVSAESGIPTFRGK-GLWNKYDPTELATFEAFEEDPLRVWKWHLWRMRLI-
-ANAKPNHAHYAISEMER---D-FLLITQNVDSLHKIAG--KLVELHGNIFEGKCRYCGKRYNEKELFLFAPKCSICGN--FVGPGVVWFGENLD---KA
FQAAEKSKIFFSIGTSALVQPAASLPLIAKK-GAVLVEINIDK-LISSYCNFVFRDSASKVLPSILSILKEH-------
>tr|F2LUD8|F2LUD8_HIPMA NAD-dependent deacetylase OS=Hippea maritima (strain ATCC 700847 / DSM 10411 / MH2) GN=Hipma_0493 PE=3 SV=1
------------------------------------IKKAKRITILTGAGISKASGIPTFRGE-GLWGKYSISEFATLEAFHKDPKKVWQWYNYRKKLI-
-KQAEPNKAHYVLVELERIF-DGFALITQNIDNLHTKAG--SVYELHGNIFEVKCL-CNKIYHDQT----DPKCKYCQS--ITRPNVVWFGESLE---KA
MALAASCDVFISVGTSGGVQPAAGLPKIAQR-GKYVVEFNAEY-AISMFADDVIIGNAEKTLPMLLNYLTR--------
>tr|A0A0N9YXX0|A0A0N9YXX0_9ARCH NAD-dependent protein deacylase OS=Thaumarchaeota archaeon MY3 GN=cobB_2 PE=4 SV=1
------------------------------------IDKSENFVFFTGAGISRESGIPTFRDK-GLWKKYDPAKLASHSAFISNPELVWDFFYSRQRLV-
-CQAECNDAHTAIGRFENTR-ENSHVITQNIDRLHQRGG--NVIELHGNIFGMVCL-CGKRKQYDY-F--EPTCPGCDN--ILKPDVVLFEEPLD---QA
IRLSSECDIMFVIGTSLNVSPANTLPYHAVK-HAVLVEINPNV-EMTSLMDFSIRASASKILTKILCVA----------
>tr|E8T3C4|E8T3C4_THEA1 Silent information regulator protein Sir2 OS=Thermovibrio ammonificans (strain DSM 15698 / JCM 12110 / HB-1) GN=Theam_1293 PE=3
------------------------------------AKNPDRVVVLTGAGISAESGIPTFRGK-GLWNRYNPTELATFEAFERDPLLVWQWYLWRMHLI-
-ANASPNPGHYALARMER---S-FLLVTQNVDGLHREAG--NIVELHGNIFEGKCRYCGKHYSEREFALF-PVCKRCGE--LVGPGVVWFGEELA---SA
LRASSAAELFFSVGTSAVVQPAASLPLVAKR-GAILVEVNPEE-PLSARCDFVFRESAASFLPRFVEALSSR-------
>tr|H5UT51|H5UT51_9MICO Putative NAD-dependent deacetylase OS=Mobilicoccus pelagius NBRC 104925 GN=MOPEL_084_00440 PE=3 SV=1
------------------------------------ARAARRVTVLTGAGMSAESGVPTFRGAGSLWEEFDPIALASPKGWDEDPELVWAWYAWRMGLA-
-RGVDPNAGHRALAQWAAAG-AEVVIATQNIDDLHERAG--VLAHVHGSLFAVRCSMCDAPYTGE---V-RPLCEECGE--YVRPGVVWFGEMLG---AA
VDACLETDLVLVVGTSGIVYPFASLPDIARG-GVPVVEINPAD-ELSEGVDHVWRATAATALPALVEALATR-------
>tr|C7NLA3|C7NLA3_KYTSD NAD-dependent protein deacetylase, SIR2 family OS=Kytococcus sedentarius (strain ATCC 14392 / DSM 20547 / CCM 314 / 541) GN=Kse
------------------------------------ARSARRVLVLTGAGASAESGVPTFRDATGLWARFDPMELATPEAWAADPAQCWAWYAWRAHLV-
-RGAEPNAGHRAIAAWQQHE-VDLRVSTQNVDGLHERSG--VLAHVHGDLFALRCARCGAASDA----Y-RPVCGRCGG--LVRPGVVWFGEMLG---AT
VTAAEWAEMVVVVGTSGMVYPAAAVPGIARE-GVPVVEVNPAG-SLPDGADHVIEAPAGQALPALVAAL----------
>tr|K6WX45|K6WX45_9MICO NAD-dependent deacetylase OS=Kineosphaera limosa NBRC 100340 GN=cobB PE=3 SV=1
------------------------------------AAAARRVVVLSGAGMSAESGVPTFRQATGLWERFDPTMLATPDAWEADRPLVWAWYAWRLGLV-
-RGVHPNAGHTALAAWGRKA--RVDIVTQNVDDLHERAG--VLAHLHGSLRAFRCEACAAPYDGP---I-RPRCPDCRA--AIRPGVVWFGEMLG---GA
VDALLEADLVLVVGTSGLVHPAAGLPDIARG-GVPVVEVNPQE-PLSAGVDLSWRITAAVGLPTLVDRLIEP-------
>tr|A0A0L8ARN4|A0A0L8ARN4_9BURK Uncharacterized protein OS=Limnohabitans planktonicus II-D5 GN=H663_14770 PE=3 SV=1
------------------------------------LHQARRIVVFTGAGMSAESGIATFRDKDSLWAQFNTRQMATPQGWRENKQRVWAWYEGRRGAV-
-MATQPNAGHAAIAQLAGTL-VQVDVVTQNVDNLHERAG--SVIHLHGSLFAPRCMACHRPGEFAPGE--EPRCQHCLG--YLRPGVVWFGEDMD---QA
EDLVDTCDAMLVVGTSGVVWPAAELPISAHN-GKFVAEINPTP-ELAKYMRVQWPTSAAQGLPQLLNLLGTA-------
>tr|I6Y036|I6Y036_PROPF Transcriptional regulator, Sir2 family OS=Propionibacterium propionicum (strain F0230a) GN=HMPREF9154_1661 PE=3 SV=1
------------------------------------ARSARRVLVLTGAGMSAESGVPTFRDEAGLWARYSPEAMATEEGWRADPELVWAWYLWRIGIV-
-NSTSPNAGHEALARWAGLI-QRLDIVTQNIDDLHERAG--VLAHLHGRLDRFHCIDCGLPGQPDLSM--RSPCDSCGS--DLRPSIVFFGEPLT---AS
VEAAQQADLTLVVGTSSIVYPAAALPGLAAR-GSFVVEVNPDP-SLD--CDLHWCTTAAIGLPQLVDQLAS--------
>tr|H5WHN5|H5WHN5_9BURK NAD-dependent protein deacetylase, SIR2 family OS=Burkholderiales bacterium JOSHI_001 GN=BurJ1DRAFT_1427 PE=3 SV=1
------------------------------------LGFAARVVVLSGAGVSAESGIATFRDA-GHWSRFDPAQLASVDGFRANPTLVWDWYAERRAGV-
-LAAEPNAGHRALGDFAR---GRLTVVTQNVDNLHQRAG--DAIRLHGDILADRWLDPCPR-----QPC-PPRCAHCGN--LRRPGVVWFGEMLG---TA
EAAVRSAGLLLVVGTSGAVWPAAGLAGLARR-GATVAIVNPHE-ELDEQAHFLLRGPSATVLPALFDGV----------
>tr|A0A0E9LD30|A0A0E9LD30_9BURK NAD-dependent protein deacetylase OS=Alicycliphilus sp. B1 GN=ALISP_2841 PE=3 SV=1
------------------------------------LRDARRVAVLTGAGVSAESGVPTFRDA-GLWARFRPEDLATEQAFRRNPGRVWDWYAERREKL-
-LGVQPNAGHHALAAFAR---GRLTLITQNVDGLHQLAG--GVLCLHGRLADDRWLDHPR-------PC-PPRCAGCGN--LVRPGVVWFGEALQ---AA
QQAVQACDVMLVVGTAGAVYPAAGLAHQARQ-GARVVVLNVGP-ELDGIAHAVLRGPSAQLLPALLDVSFHF-------
>tr|E4WFF2|E4WFF2_RHOE1 Putative secreted NAD-dependent deacetylase OS=Rhodococcus equi (strain 103S) GN=REQ_15790 PE=3 SV=1
------------------------------------ARAARKVVVFSGAGMSAESGIPTFRDATGLWERFSPEQLASPEGWERDRGLVWAWYQWRTGLV-
-RRVQPNAGHRAVAEWARHT--PVEIVTQNVDDLHERAG--VAAHLHGSLFAPRCGDCGAPHPSD---G-PPECTRCGG--SVRPGAVWFGEALD---RA
ENAVDECDLMVVVGTSGVVYPAAGLPLRAIG-GATVVEINPQA-DLSPHVQYSWRTTAAEGLPALVARS----------
>tr|M3TF40|M3TF40_9ACTN NAD-dependent deacetylase OS=Gordonia malaquae NBRC 108250 GN=cobB PE=3 SV=1
------------------------------------IAHAERTVVFTGAGMSAESGIPTFRDAVGMWENHDPMTLASPEGWTADRDLVWDWYAQRANDV-
-RRVDPNDGHIALAQLAVAA-RAVRVITQNVDDLHERAG--VASHLHGSLFAPRCESCRRPESADT----IPMCPLCCD--SLRPGVVWFGELLD---AA
SDAVAACDLMIVIGTSGVVQPAASLPERAHV-GVPIIEVNPEP-ELTRLATIRLAGSAAETLPRVIG------------
>tr|S3YCD5|S3YCD5_9ACTN Uncharacterized protein OS=Propionibacterium sp. oral taxon 192 str. F0372 GN=HMPREF1531_00769 PE=3 SV=1
------------------------------------AQAARRVLVLSGAGMSAESGVPTFRDATGLWHRYDPAELATPQAWARDPGLVWAWYEWRRSLV-
-AACQPNAGHRALAEWARIA--EMSVVTQNVDDLHERAG--VVVHLHGSLFAHRCDSCGAPVELP---V-RPVCVHCTG--RIRPGVVWFGEALG---EA
MTQIEASDLVMVVGTSGMVHPAAALPGLAVS-GVPVVEINPNP-GLPA--DVHWPVTAAVGLPALVDQLG---------
>tr|A0A098BY27|A0A098BY27_9NOCA NAD-dependent protein deacylase OS=Rhodococcus ruber GN=cobB PE=3 SV=1
------------------------------------ARRARRIAVLTGAGMSAESGVPTFRDATGLWERFDPADLATPEAWERDRASVWAWYQWRVALV-
-RRVQPNDGHRALADWGQAV--ELSIVTQNVDDLHERAG--VLSHLHGSLFSPRCADCGTPADPPE----RPDCGACGG--DVRPGVVWFGEPLG---AA
TASVLAADLVFVVGTSGIVYPAAGLPSLARR-GVPVVEVNPEE-GLSDQMDEVWRTTAAVGLPQLVAAVAAD-------
>tr|A0A095ZCG7|A0A095ZCG7_9CORY NAD-dependent deacetylase OS=Corynebacterium freneyi DNF00450 GN=HMPREF1650_07735 PE=3 SV=1
------------------------------------ARNARRVEFFTGAGMSAESGLATFRDATGLWSKVDPQAMANFDAWRNDPATIWPWYLWRMKLA-
-RQAEPNAGHKAIAAWCDTL-GWGHVTTQNIDDLHERGG-DSIAHLHGSLFAFRCDHCGAAAAE-PEL--KPFCDVCEL-GFVRPGVVWFGESLP---EA
ETHARHCDLMVVVGTSGVVFPAAGLPLMAVS-GIPVIEISPDD-DFTPHATHSWRTTAATGLPALARAAGVD-------
>tr|A0A0M2CWU8|A0A0M2CWU8_9MICC NAD-dependent deacetylase OS=Kocuria sp. UCD-OTCP GN=H488_0105980 PE=3 SV=1
------------------------------------ARSARTVTVLSGAGMSAESGVPTFRDATGLWARWSPEELATPEAWDADPGLVWSWYLWRARQV-
-RRLRPNAGHRAIARWADRA--RVHVVTQNVDDLHERAG--VLAHLHGSLFAFRCSDCGAPFPERLLPLARPVCPSCGG--AVRPAVVWFGEQLG---RA
AAAVAEAELVLVVGTSGLVQPAASLPLIAAG-GTPVVEINPED-APTPHADRTVRAGAAEALPRLLPPWGDR-------
>tr|A0A0J1BP81|A0A0J1BP81_9MICC NAD-dependent deacetylase OS=Kocuria sp. SM24M-10 GN=ABL57_19060 PE=3 SV=1
------------------------------------ARSARTVTVLTGAGMSAESGVPTFRDATGLWARWSPEELATPEAWEADPELVWSWYLWRARQL-
-CRLRPNAGHRALARWAGRA--RVQVVTQNVDDLHERAG--VLAHLHGSLFAFRCSACGAPFPGALVPLSRPMCPVCGG--AVRPSVVWFGELLG---RG
ADAVAEADLVLVVGTSGLVQPAASLPLIAAG-GIPVVEVNPED-ALTPHADWVVRARSAEALPRLLP------------
>tr|V9XNC5|V9XNC5_9NOCA NAD-dependent deacetylase OS=Rhodococcus pyridinivorans SB3094 GN=Y013_24340 PE=3 SV=1
------------------------------------ARSARRVAVLTGAGMSAESGVPTFRDATGLWENFDANALATPAAWADDPATVWAWYQWRVALV-
-RRVQPNAGHRALTDWARAA--HVQIVTQNVDDLHERAG--EVTHLHGSLFAPRCSRCERAVDLPD----RPSCPACGG--DGRPGVVWFGEMLD---TA
TESLREADLLLVVGTSGVVYPAAGLPSLARS-GVPVVQIDPRE-DLSDQVDHAWRTTAAVGLPALVDALRIG-------
>tr|V8CV43|V8CV43_9ACTN Uncharacterized protein OS=Williamsia sp. D3 GN=W823_19045 PE=3 SV=1
------------------------------------VRGAEWVTVCSGAGMSAESDVPTFRDATGLWERFDPTTLATPEAWSDDPALVWAWYQWRAHLV-
-RRAFPNPGHHAVAEWARR--RTVMVVTQNVDDLHERAG--VTAHLHGSLFEPRCSHCGLPYAGTD----RPICPNCLS--PVRPGVVWFGESLD---RA
ADASAGCDLLIVVGTSNMVYPAASLPERALA-GIPVIEINPEP-PLSRNVTYFLQTTAAVGLPALLNVIADD-------
>tr|K6VYJ9|K6VYJ9_9ACTN NAD-dependent deacetylase OS=Gordonia rhizosphera NBRC 16068 GN=cobB PE=3 SV=1
------------------------------------VRSARWVTVFSGAGMSAESGIATFRDATGLWERYDPAQLATPEAWEADPALVWAWYQWRARLV-
-RDTEPNAGHHALAALAAD--RAVMVVTQNVDDLHERAG--VVSHLHGSLFAPRCSHCGRPYRGTD----RPMCPHCLA--PVRPGVVWFGEPLE---KA
ENAFAVTDVVIVVGTSGIVYPAAGLPERALA-GVPVIEFNPEP-ALSDRVTHSVRASAALGLPALLEAVRAG-------
>tr|G7GMQ9|G7GMQ9_9ACTN NAD-dependent deacetylase OS=Gordonia amarae NBRC 15530 GN=cobB PE=3 SV=1
------------------------------------VRQAHWITVFSGAGMSAESGVPTFRDATGLWERFDPAALATVEAWDDDPALVWGWYLWRMKLV-
-GDAQPNPGHRAIAGLAD---RTVMVVTQNVDDLHERAG--VISHLHGSLFEPRCSVCAAPYHGTGTR--RPACHECLS--PVRPGVVWFGEPLD---RA
EHTIAGSELVLVVGTSGIVYPAAELPERALA-GTPVIEFNIDE-ALSPYVTLSVRTSAAVGLPALLDAVRG--------
>tr|M0QKM3|M0QKM3_9ACTN NAD-dependent deacetylase OS=Gordonia soli NBRC 108243 GN=cobB PE=3 SV=1
------------------------------------VRAAEWVTVFSGAGMSAESGIPTFRDATGLWERFDPAQLATPEAWSGDPALVWGWYQWRARLV-
-RDTEPNAGHRALTALAAD--RSVLVVTQNVDDLHERAG--VVAHLHGSLFAPRCSHCETPYRGVD----RPTCPICLS--PVRPGVVWFGEALD---RA
EQAIAAAQVVIVVGTSGIVYPAASLPERAAG-GIPVIEVNPVA-ALDDVVAHRIAAPAGVGLPALVRAVAER-------
>tr|D5UWS1|D5UWS1_TSUPD Silent information regulator protein Sir2 OS=Tsukamurella paurometabola (strain ATCC 8368 / DSM 20162 / JCM 10117 / NBRC 16120 
------------------------------------VRDAESIVVLTGAGMSAESGIATFREATGLWARYDPEEIASVDAWTRDSALVWGWYQWRGYIA-
-RQAEPNNGHIALAELGTR--RSVSIVTQNIDDLHERAG--VTAHLHGSLFAPRCEYCGTPYLGSDAER-RPTCMQCLS--QVRPGIVWFGEPLE---RA
EAAVIAADLVLVIGTSGLVYPAARLPEMALE-GIPVVEINPEP-PLSARATVAWNTTAATGLPALVAAVTSG-------
>tr|H5TGI2|H5TGI2_9ACTN NAD-dependent deacetylase OS=Gordonia otitidis NBRC 100426 GN=cobB PE=3 SV=1
------------------------------------LAGAEWIIVFTGAGMSAESGVPTFRDATGLWENFDPEQLASPEAWNADPALVWGWYQWRAHLV-
-SEAEPNAGHVALTALAESA-PSVMVVTQNVDDLHERAG--VVSHLHGSLFAPRCSRCGHPYQGTD----PPACPICLS--PVRPGVVWFGESLD---RA
EQVFDAADAIIVVGTSGIVYPAAALPERAAA-GIPVIELNPQP-GLSSIATHSIRTTAARGLPDIVERVRAA-------
>tr|H5U4Q7|H5U4Q7_9ACTN NAD-dependent deacetylase OS=Gordonia sputi NBRC 100414 GN=cobB PE=3 SV=1
------------------------------------LAGAEWITVFTGAGMSADSGVPTFRDATGLWENFDAEQLATPQAFNADPALVWGWYQWRAHLV-
-RQAAPNAGHLALSALAEPT-PSVMVVTQNVDDLHERAG--VVSHLHGSLFAPRCSRCGHPYEGRD----PPACPICLS--PVRPGVVWFGEPLE---RA
EQVFDVADAVLVVGTSGIVYPAAALPERAAN-GIPIIELNPEP-GLSSVATHSIRTTAARGLPEIAERVRAA-------
>tr|H0RIE1|H0RIE1_9ACTN NAD-dependent deacetylase OS=Gordonia polyisoprenivorans NBRC 16320 = JCM 10675 GN=cobB PE=3 SV=1
------------------------------------VRAAEWVTVFSGAGMSAESGIPTFRDVTGLWENFDPTTLATPQAWRDDPALVWGWYQWRAGQV-
-RRREPNAGHRALAELRHAG-RAVMVVTQNVDDLHERGG--VTSHLHGSLFAPRCSRCGHRFTETDPI--RPRCPVCGE--LVRPGVVWFGEPLQ---RA
DAAFRATDVVLVIGTSGIVYPAASLPERAAA-GIPVIEINPEP-ALTPSVQQRIPVGAAVALPALVQALEVP-------
>tr|W0SFX4|W0SFX4_9RHOO Silent information regulator protein Sir2 OS=Sulfuritalea hydrogenivorans sk43H GN=SUTH_01888 PE=3 SV=1
------------------------------------LHDCQKVVVFTGAGISAESGIPTFRDA-GLWSKFNPQDVASTEAFRKNPQLVWDWYVHRAEFV-
-RNAEPNPGHKAVSTLQA---D-LTVITQNIDNLHQRAA--NVLELHGSLFRLKAFVCDGYATYDEC--DAPRCPGCGA--LLRPDIVWFGEPLD---GA
TRLADTCDLLICIGSSLEVQPAASIPVRAKL-GATIIEINPEP-SLSSHADVFLQGKAAEILPAFVNVVWNN-------
>tr|A9WFY1|A9WFY1_CHLAA Silent information regulator protein Sir2 OS=Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl) GN=Caur_2936 PE=3
------------------------------------LSTARHVTVLTGAGVSAESGIPTFRDA-GLWSHFDPEELASPAGFARNPALVWRWYAERRVKA-
-CTAQPNPAHHALADLAT---PRLTLVTQNIDGLHQRAG--QVIELHGNIHRARCTVDGS-------IH--PQCPNCGA--LLRPDVVWFGEYLG---AA
YAATLDCDVFCSIGTSGVVEPAASLPRIALS-GATVLILNLEQ-TTARSPLFTVYGKAGEVLPRLVAAVRSM-------
>tr|A0A0M9FZA0|A0A0M9FZA0_9TRYP Putative NAD dependent deacetylasemidazole (Cobb) protein OS=Leptomonas pyrrhocoris GN=ABB37_06041 PE=4 SV=1
------------------------------------LAHARRIVVFSGAGICAESGINTFRDPVGVWKNKIAALFAVPFGWRWMPTMAWWGYKKFHTPI-
-AAAQPNEGHRTVARLRDEL-DAVQVITQNVDALHQRAG-EFVYEVHGSVWRHRCIKNGHPMDLL-----PPRCA-CGS--PARPDVVLFTESLDKSEVA
VCGLRAGDVLLVVGTSGVVQPGASLPELCA--GVVKIEVNIEH-AHSKGMNVCIRQSSSIALPLLLQLAKEG-------
>tr|S9V959|S9V959_9TRYP NAD-dependent deacetylase OS=Angomonas deanei GN=AGDE_06586 PE=4 SV=1
------------------------------------LSRAKRVAVFTGAGMSAESGINTFRDPVGVWKNKIAYLFGTPYGWRWTPGWGWSNYRRFHEPI-
-FKAQPNAGHYALANMAAML-ENVKIATQNVDYLHQRAG-EQVFEVHGSVFRHRCVKNGHPIDIP-----PPKCAGCGS--SARPDAVLFTETLDGAEKV
MRELQRGDVLLVIGTTGQVYPAAGLPDMVR--GVTKIELNIEP-NHTAHMDIFVKESSAVSLPKILEEAKKL-------
>tr|D5SW63|D5SW63_PLAL2 Silent information regulator protein Sir2 OS=Planctopirus limnophila (strain ATCC 43296 / DSM 3776 / IFAM 1008 / 290) GN=Plim_1
------------------------------------LRKAHRIVVFTGAGISSESGIPTFRDNDGFWQRFPPERFATWKGLLTDRHSVAQFIFNVIEPI-
-AKSEPNAGHAAVASIQQ---VSTTVVTQNIDGLHQSAG-TSVLEIHGSLMEVVDVTSGEIVQK-LDR--KP-F-DWFG--RHRPNLVLFGDDLPAWAKA
CQASRECDVLLSIGTSGAVYPAALLPGTAAA-GATVISIDPQ-----PMEGCWLKGKAGDLLPKLISDAFGS-------
>tr|F0SHK0|F0SHK0_RUBBR NAD-dependent deacetylase OS=Rubinisphaera brasiliensis (strain ATCC 49424 / DSM 5305 / JCM 21570 / NBRC 103401 / IFAM 1448) GN
------------------------------------LRKAKRVVVFSGAGMSAESGIPTFRDADGFWGQFPPEEFATWDGLIAEPRQVARFAWHVIDPI-
-ARAEPNAAHRAAAAIEQ---TQVTVITQNIDGLHHDAG-SNIWELHGSLLDVINAPERRIVKR-FSR--RP-F-DFRG--RHRPNVVLFGDDLPDWTYS
CREVKSCDVLLSVGTSGSVFPAAFLPGRAEL-GATVVSISPT-----ACDGCWLQGNASDVLPRLVKAAWPD-------
>tr|D9TDQ8|D9TDQ8_MICAI Silent information regulator protein Sir2 OS=Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 
------------------------------------LAAARRPVVFTGAGMSAESGVPTFRDATGLWQRYDPQELATPAAFRADPALVWGWYEARRRGV-
-RRALPNPGHRAVAAIAARL-PDTVVITQNVDDLHERGG--APVRLHGSLFAPRCSACA-PAPIPEDAA-PPACAGCGA--PVRPGVVWFGEALA---AA
VEAASGCDLLLTVGTSALVHPAAEIPLVAAR-GAPVVQVNPVP-PLDAICAVNLRGPAGEVLPALVRAAWPD-------
>tr|A0A0M2S697|A0A0M2S697_9ACTN NAD-dependent deacetylase OS=Micromonospora sp. HK10 GN=LQ51_06065 PE=3 SV=1
------------------------------------LRRARRVVVFTGAGMSAESGVPTFRDATGLWRRFDPHALATPEAFDADPALVWGWYEWRRQLV-
-RRAEPHPGHRAVAAIEARV-PT-VLITQNVDDLHERAG--APLHLHGSLFAARCSACD-PAPVPDGA--RPRCARCAG--PVRPGVVWFGEALD---AA
VDAASGCDLLLTVGTSGLVHPAAEIPLVTAR-GGSVIQVNPER-PLDPVAAVNLRGPAAEVLPALVDAAWGA-------
>tr|S6SR30|S6SR30_PSESF NAD-dependent deacetylase OS=Pseudomonas syringae pv. actinidiae ICMP 19096 GN=A245_44665 PE=3 SV=1
------------------------------------LRTAQHVVVFTGAGASAESGIPTFRDATGLWERFDPGQLATSEAFRADPSLCWGWYEWRRHKV-
-LRAQPNEGHFAIAELAKHV-PRLTVVTQNVDDLHERAG--NVIHLHGSLHSPRCIDCGQPHTLPLTS--RPRCGACSG--YVRPGVVWFGEMLD---AG
LAAAQECDVFLSIGTSGIVYPAAELPLRALG-GATVVHINPVR-EISSQEHS-LEGPASVMMQSLLREAFGE-------
>tr|V7D5Q9|V7D5Q9_9PSED NAD-dependent deacetylase OS=Pseudomonas taiwanensis SJ9 GN=O164_28245 PE=3 SV=1
------------------------------------LREAKRVVVFTGAGVSAESGIPTFHDATGLWERFDPAQLATVEAYRADPSLCWGWYEWRRCKV-
-LQAQPNDAHLAIAELAQHV-QKLTVVTQNVDDLHERAG--GVIHLHGSLHSPRCIDCGITHEAVLAC--RPRCHSCNG--YIRPGVVWFGEMLA---AG
LEAAEDCDLFFSIGTPGIVFPAAELPLRALS-GASVVHINPVR-EISDQEHF-LQAPASGM-RTLIGAAFG--------
>tr|A0A099SL32|A0A099SL32_PSEUB NAD-dependent deacetylase OS=Pseudomonas syringae pv. tomato GN=NB04_26100 PE=3 SV=1
------------------------------------LRKAQHVMVFTGAGASAESGIPTFRDATGIWERFDPARLATSEAFRADPALCWGWYEWRRHKV-
-LQAQPTGAHLAIAELARYV-PKLTVVTQNVDDLHERAG--DVIHLHGSLHSPRCIDCELTYTLPVTS--RQRCTACDG--YVRPGVVWFGEMLD---AG
LAAAEECDVFLSIGTSGVVYPAAELPLRALG-GATVAHINPVR-DISSQEHF-LQGPASLMMQTLLRDAFG--------
>tr|A0A0Q0HDN1|A0A0Q0HDN1_9PSED NAD-dependent protein deacylase OS=Pseudomonas syringae pv. tagetis GN=ALO44_03609 PE=4 SV=1
------------------------------------LRVAKHVVVFTGAGASAESGIPTFRDATGLWENFDASKLATAEAFRADPGLCWGWYEWRRHKV-
-IQAQPNGAHYAIAQLANHV-PKLTVITQNVDDLHERAG--AVAHLHGSLHSPRCIDCSAAHEAPLPS--RPRCTRCNG--YVRPGVVWFGEMLD---NA
MTAAKDCDMFISIGTSGIVYPAAELPFAALA-GAKVVHINPAR-AISSQEFF-VEGTAAHSMTALVERAFL--------
>tr|A0A0A6R234|A0A0A6R234_9GAMM NAD-dependent deacetylase OS=Methylomonas denitrificans GN=JT25_08420 PE=3 SV=1
------------------------------------LRDAQHLVILTGAGVSAESGIPTFRDATGLWARYDPQQLASESGFRADPALVWGWYEWRRAKV-
-MNSSPNPAHRTIAQYQQMV-PKLTLITQNVDDLHERAG--SVIHLHGSLHTAHCIACATPFALNATP--LPRCPACGD--YIRPGVVWFGESLD---AA
EAAAQHCDVLMSIGTSALVYPAASLPLVALN-GAKIIQLNPDK-NLDAKAHFNLHGKAGDLLPALLQAVYAQ-------
>tr|F3FJV2|F3FJV2_PSESX Cobalamin biosynthetic protein OS=Pseudomonas syringae pv. japonica str. M301072 GN=PSYJA_16517 PE=3 SV=1
------------------------------------LRNAQRVVVFTGAGASAESGIPTFRDATGLWERFDPAQLATSDAFRADPSLCWGWYEWRRLKV-
-LQAQPNGAHLAIAEMARLV-PKLTVVTQNVDDLHERAG--DVIHLHGSLHSPRCIDCGLPYTLPLTS--RPRCSACSG--YVRPGVVWFGEMLD---AG
LAAADDCDIFLSVGTSGIVYPAAELPLRALG-GATVVHINPVR-EISSQEHF-FQGPASVMMQSLLREAFGG-------
>tr|A0A0R2ZX49|A0A0R2ZX49_9PSED NAD-dependent deacetylase OS=Pseudomonas orientalis GN=TU82_12350 PE=4 SV=1
------------------------------------FREARHVVVFTGAGASAESGIPTFRDATGLWERFDPAQLATCEAFRADPALCWGWYEWRRQKV-
-GQAKPNGAHLAIAELARHV-PNLTVITQNVDDLHERAG--DVIHLHGSLHSPRCIDCGQPYTLPLTS--RLRCSACNG--YVRPGVVWFGEMLS---AG
LAAAEECDVFLSIGTSGIVYPAAELPLRALG-GATVAHVNPAR-DISGQEHF-LVGPASVMMQSLLREAFGD-------
>tr|A0A0M3D1M1|A0A0M3D1M1_PSEPU NAD-dependent deacetylase OS=Pseudomonas putida GN=PU99_03800 PE=3 SV=1
------------------------------------LREAKHVVVFTGAGASAESGIPTFRDAIGLWERFDPAQLATSEAFRADPALCWGWYEWRRHKV-
-LQAQPNGAHIAIAELAKHV-PKLTVVTQNVDDLHERAG--DVIHLHGSLHSPRCIDCGQTYTLPLTS--RPRCTACTG--YVRPGVVWFGEMLG---AG
LTAAEECDVFLSIGTSGIVYPAAELPLRALG-GATVVHINPVR-DISSQEHF-LQGPASAMMQSLLREAFGD-------
>tr|A0A0K2JZY3|A0A0K2JZY3_9MICC NAD-dependent deacetylase OS=Kocuria palustris GN=KPaMU14_12015 PE=3 SV=1
------------------------------------CRSASRVAVLSGAGISAESGVPTFRAPTGLWARYSPQELATPEAWEADPELVWAWYMQRARYV-
-RQCAPNAGHRALVSWSEYA--DVTIATQNIDDLHERAG--DVSHLHGSLYSFRCSHCGRPADQWQVALRPPECLECDG--PIRPDVVWFGEALG---DA
ESAMASAELVLVIGTSGLVQPAASLPLTALG-GVPVVEINPEP-GFSAQADHSVQLTSGTALPLMLSAARRS-------
>tr|A0A0L6I6V0|A0A0L6I6V0_9BURK NAD-dependent deacetylase OS=Achromobacter piechaudii GN=AKG08_17840 PE=3 SV=1
------------------------------------LRSAQRVVVFTGAGVSAESGIATFRDATGLWSRFDAQALATPEAFRAHPDVVWGWYEWRRAQA-
-RRAAPNAAHEAIAALHRHV-PDLTVITQNVDDLHERAG--QVVHLHGSLHAPRCSRCGAPQAVGDTGT-RPSCTQCGA--PVRPGVVWFGESLD---TA
LRAAQQCDLLFSIGTSALVYPAAELPQRALA-GATVVQVNPNP-PLDAHAHCNLHGAAAEVMPRVLAAAFGQ-------
>tr|A0A0L0R510|A0A0L0R510_9BURK NAD-dependent deacetylase OS=Achromobacter spanius GN=AFM18_20205 PE=3 SV=1
------------------------------------LRGAQRVVVFTGAGVSAESGIATFRDATGLWSRFDAQALATPEAFRAHPDIVWGWYEWRRAQV-
-LRAAPNAAHHAIAALARHV-PELTVITQNVDDLHERAG--QVVHLHGSLHAPRCSACAAPQAFPIA---RPACARCGQ--PVRPGVVWFGESLE---IA
LRAAEQCDLLFSIGTSALVYPAAELPQRALA-GATVVQVNPNL-PLDAQAHCNLHGAAADVMPRVLAAAFA--------
>tr|A0A0M7K7D1|A0A0M7K7D1_9BURK NAD-dependent deacetylase OS=Achromobacter sp. GN=cobB_2 PE=3 SV=1
------------------------------------LRGAQRVVIFTGAGVSAESGIATFRDATGLWSRFDAQALATPEAFRAQPDVVWGWYEWRRAQV-
-LRAAPNAAHHAIAALAQHV-PELIVVTQNVDDLHERAG--HVVHLHGSLHAPRCSVCAAPYVFGDE---RPACTACGA--PVRPGVVWFGESLD---TA
LRAAEQCDVLFAIGTSALVYPAAELPQRALA-GATVVQVNPGV-PLDPHAHCNLHGLAADVMPRVLAAASEH-------
>tr|H0FF91|H0FF91_9BURK Sir2 family transcriptional regulator OS=Achromobacter arsenitoxydans SY8 GN=KYC_27287 PE=3 SV=1
------------------------------------LRQARRVVVFTGAGVSAESGIATFRDATGLWSRFDAQALATPEAFAADPDIVWGWYEWRRAQV-
-LRAAPNAAHRAIADLARHV-PELAVITQNVDDLHERAG--CVTHLHGSLHAPRCSRCASPQAFAVDV--RPACTACGA--PVRPGVVWFGESLQ---DA
LRAAQGCDLLFSIGTSSLVYPAAELPRLALA-GATVVQVNPAA-PLDAQAHHNLRGAAADVMPCLLASAGFG-------
>tr|A0A0M7KIR7|A0A0M7KIR7_9BURK NAD-dependent deacetylase OS=Achromobacter sp. GN=cobB_2 PE=3 SV=1
------------------------------------LARARRVTVFTGAGVSAESGIATFRDPTGLWARFDARALATPEAFAAQPDLVWGWYEWRRAQV-
-ERAEPNAAHRAIAALARRI-PALTLVTQNVDNLHERAG--AVIHLHGSLHAPRCSACGHAARIAPRAD-APACVECGA--PIRPGVVWFGESLG---AA
QQACDDCDLFFSIGTSALVYPAAELPLRAAR-GATVVQVNPAP-PLDAHADFNLRGAAADVMPRLLAAAGF--------
>tr|J4QPZ4|J4QPZ4_9BURK Silent information regulator protein Sir2 OS=Achromobacter piechaudii HLE GN=QWC_17962 PE=3 SV=1
------------------------------------LHGAQRVVVFTGAGVSAESGIATFRDATGLWSRFDAQALATPEAFRAHPDVVWGWYEWRRAQA-
-LRAEPNAAHRAIAALARHV-PELIVVTQNVDDLHERAG--QVAHLHGSLHAPRCSSCGTPQALSGG---RPACTHCGA--PVRPGVVWFGESLD---DA
LRAAEQCDLLFSIGTSALVYPAAELPQRALA-GATVVQVNPTV-PLDRQAHCNLHGAAADVMPRLLAAAFGA-------
>tr|A0A095WQ12|A0A095WQ12_9BURK NAD-dependent deacetylase OS=Achromobacter sp. RTa GN=JL37_23780 PE=3 SV=1
------------------------------------LQEARRVVVFTGAGVSAESGIATFRDATGLWSRFDAQALATPEAFRSHPDIVWGWYEWRRAQV-
-LRAEPNAAHRAISQLARHV-PGLTVVTQNVDDLHERAG--GVAHLHGSLHAPRCSACEAPQIFADGI--RPACTRCGS--AVRPGVVWFGESLD---AA
IHAAEHCDLLLSIGTSALVYPAAELPQRALA-GAMVAQINPAA-PLDARAHHNLRGAAAEIMPGLLASAGFE-------
>tr|A0A0A5J891|A0A0A5J891_ALCXX NAD-dependent deacetylase OS=Alcaligenes xylosoxydans xylosoxydans GN=MC81_14025 PE=3 SV=1
------------------------------------LRQARRIVVFTGAGVSAESGIATFRDATGLWSRFDAQALATPEAFQAQPDVVWGWYEWRRAQV-
-LRATPNAAHRAIAAWAQHV-PELLVVTQNVDDLHERAG--RVAHLHGSLHAPRCSACGAAHTFAQEL--RPACSQCGA--PVRPGVVWFGESLH---LA
MLAAEQCDLLLSIGTSALVYPAAELPQRALA-GAIVAQINLAA-PLDARAHHNLRGAAADVMPRLLASAGFG-------
>tr|A0A0Q8XUM6|A0A0Q8XUM6_9BURK NAD-dependent deacylase OS=Achromobacter sp. Root83 GN=ASE30_00370 PE=4 SV=1
------------------------------------LRQARRVVVFTGAGVSAESGIATFRDATGLWSRFDAQALATPEAFRAHPDIVWGWYEWRRAQV-
-LRAMPNAAHRAIAELARHV-PELAVITQNVDDLHERAG--RVTHLHGSLHAPRCSVCGSPYAFATDVD-RPACAHCSA--PVRPGVVWFGESLD---AA
VHAAQRCDLMFSIGTSALVHPAAELPGHALA-GATLVQVNPAA-PLDAQAHHNLRGAAADVMPRVLASAGFA-------
>tr|A0A0Q8JTR6|A0A0Q8JTR6_9BURK NAD-dependent deacylase OS=Achromobacter sp. Root170 GN=ASD87_12240 PE=4 SV=1
------------------------------------LRSARRVVVFTGAGVSAESGIATFRDATGLWSRFDAQALATPEAFREHPDLVWGWYEWRRAQV-
-LRAAPNAAHHAIAALAHHV-PELAVITQNVDDLHERAG--AVTHLHGSLHAPRCSRCGAPQAFATDL--RPACTECGA--PVRPGVVWFGESLQ---DA
TLAVQQCDLLFSIGTSSLVYPAAELPRLAVA-GATVVQVNPAA-PLDAIAHHNLRGAAAQIMPAVLAAAQFT-------
>tr|A0A0P9B440|A0A0P9B440_VARPD NAD-dependent protein deacetylase OS=Variovorax paradoxus GN=APR47_27135 PE=4 SV=1
------------------------------------EVQFDKLVVFSGSGVSAESGLPTFRDS-GLWNSHAWEEVSSPRGWQRNPEAVLAFYNERRLKA-
-WHAVPNAAHQAIASLEA---YDVVVITQNVDELHERAG--QVIHVHGEIAYARGS-EARRYRI-E----IQLCED-GA--QLRPDVVWFGEEVQ---EA
RLHIASAGKVLVVGTSLSVFPVASLVKAARG-RAEKVLVSLGV-K-PPYG-KCLRGKATELVPALAAQWLAE-------
>tr|A0A0Q9CH39|A0A0Q9CH39_9GAMM NAD-dependent deacylase OS=Lysobacter sp. Root916 GN=ASE35_00705 PE=4 SV=1
------------------------------------EIQANKVVVLSGSGLSAESGLPTFRDS-GLWNNYSWQEVASLEGWRKRPEAVLAFYNERRAKA-
-WAAEPNPAHLAIAALES---YEVVVVTQNVDELHERAG--QVIHLHGELAYARST-DTKRYRI-K----IQVCEE-GS--QFRPDIVWFGEQTQ---LA
WQHIATAAKVMVVGTSLTVYPAATLVDAAAD-SAEKVLISLEM-E-IPYG-EFIRGNAAQAVPRLAKAWLER-------
>tr|A0A0N8PGL1|A0A0N8PGL1_VARPD NAD-dependent protein deacetylase OS=Variovorax paradoxus GN=APR47_38185 PE=4 SV=1
------------------------------------TVQLRKIVVLSGSGVSAESGLPTFRDA-GLWNNHPWQELASPEGWQRHPETVQAFYNERRQKA-
-WAAQPNAAHAAIASLEP---YEVVIVTQNVDALHERAG--QVLHIHGELAYARGT-ERHRYRI-D----IQFCED-GT--QLRPDIVWFGESVQ---EA
LMHVSDAARVLVVGTSLAVQPAASLARYAHH-SAEKVLVSLDM-E-VPRG-DFMRGKATEQVPALVARWLAQ-------
>tr|A0A0Q7HRR5|A0A0Q7HRR5_9BURK NAD-dependent deacylase OS=Variovorax sp. Root434 GN=ASD05_24735 PE=4 SV=1
------------------------------------RVQPNKIVVLSGSGVSAESGLPTFRDA-GLWNSYSWQELASPDGWQRHPEAVLAFYNERREKA-
-WQAQPNAAHIAIASLEP---YEVVIVTQNVDALHERAG--NVLHLHGQLAYARGT-ESKRYRI-D----IQLCED-GT--QLRPDIVWFGEAVQ---EA
EEHVATAARVLVVGTSLTVHPAASLVRYADR-TAQKVLVALDM-E-VPHG-TFLQGRATEVVPALALKWLSE-------
>tr|K2J475|K2J475_9GAMM Uncharacterized protein OS=Gallaecimonas xiamenensis 3-C-1 GN=B3C1_00185 PE=4 SV=1
------------------------------------DGSKRKVVVFSGAGLSADSGLDTFRDQ-GLWHQVPVALVATPEGWQQDPAFVTAFYNDRRRDI-
-AKAQPNAAHLAIARLEQ---FEVTVITQNLDDLHERAG--RVLHLHGEITKARS--AAQLYEI-G----LERDAA-GG--LLRPHVVWFGEAPL---EA
LAAIKVADKVLVVGTSLIVQPAASLLKKARY-QADKRIVALDI-S-KPFG-RFIRGRAANVVPAIACDWLA--------
>tr|A0A0N0G822|A0A0N0G822_PSEAV NAD-dependent deacetylase OS=Pseudomonas amygdali pv. lachrymans GN=AC499_0847 PE=4 SV=1
------------------------------------EINPNKIVVFTGSGVSVESGLATFRDA-GLWEEHRIEDVASIDGWRRDPEQVLEFYNQRRKAV-
-LKAEPNAAHLAIAALES---YETVVITQNIDDLHERAG--NVLHLHGQVLKSRS--VNLSYDQ-T----MDLCEE-GH--QLRPDIVWFGEHLG---EA
VLHLKTAGRVLVVGTSLNVQPAAGLLKHGRY-HAEKIVVSYEV-K-LPFG-KFLRGRAGGLVPLITSAWLEG-------
>tr|J2IEA6|J2IEA6_9ALTE Silent information regulator protein Sir2 OS=Alishewanella aestuarii B11 GN=AEST_18460 PE=3 SV=1
------------------------------------NQQATKIVIISGAGISAESGLATFRDP-GLWQQYALEDLATPQAFARNPALVHRFYNSRRIQA-
-AKAEPNAAHLAIAKLEQ---FNVVVVTQNVDDLHERAG--KVLHLHGKLNEARS--RNLIEVI-G----LELAAD-GS--ALRPNIVWFGEEVP---PA
IKEIASADKILVVGTSLQVYPAASLLFYARK-GAEKVLINLEA-D-NDAG-QFIQGKAATEVPKLVEKWLAK-------
>tr|A0A086D316|A0A086D316_9GAMM NAD-dependent protein deacetylase OS=Gammaproteobacteria bacterium MFB021 GN=GY26_11190 PE=3 SV=1
------------------------------------ETRMPHLVVLTGAGISAESGLKTFRDG-GLWENHRVEDVATPEAWARDPASVLRFYDERREQT-
-RRARPNPAHRALAELETA--FRVDVITQNIDDLHERAG--QVLHLHGEILLARS--VDLRYPL-T----IDLCDK-GS--QLRPDVVWFGEAVP---EA
CDIVAEADALLVVGTSLAVMPAALLLEQAPL-DAPCWLIDPQA-DLAPPG-APIAEPASQGVPTLVARWKAQ-------
>tr|H0J534|H0J534_9GAMM NAD-dependent deacetylase OS=Halomonas sp. GFAJ-1 GN=MOY_13760 PE=3 SV=1
------------------------------------MTAPPHLVVFTGSGISVESGIRSFRAS-GLWEEYPLEEVATPQGWRRDPERVLEFYNQRREQI-
-RKAKPNAAHKALAALEKE--FKVSVVTQNIDDLHERAG--DVLHLHGEILQARS--VDLRYRL-P----IDVCDM-GS--QLRPDVVWFGEPVP---DA
CELVSEADFFLVVGTSLAVMPAASLLSYIDY-DTPCALVDPNA-SLTPPG-LAINTTAGEGVPALVNQWRKQ-------
>tr|A0A0D7UU57|A0A0D7UU57_9GAMM NAD-dependent protein deacetylase OS=Halomonas meridiana GN=VE30_14395 PE=3 SV=1
------------------------------------MTSAPHLVVFTGSGISAESGIQTFRAS-GLWEDHPVEEVATPQGWRQDPERVLAFYNQRRDQI-
-RRAKPNAAHKALAALEQD--FKVSVITQNIDDLHERAG--HVLHLHGEILKARS--VDLRYPL-S----IDVCDK-GS--QLRPDVVWFGEAVP---EA
CELVSQADFLLVVGTSLAVMPAASLLTYIDY-DTPCALVDPDA-ELSPPG-LAINTTAGEGVPALVHQWRKQ-------
>tr|A0A0F4QZU1|A0A0F4QZU1_9GAMM NAD-dependent protein deacetylase OS=Halomonas sp. S2151 GN=TW86_11555 PE=3 SV=1
------------------------------------MSKAPHLVVLTGAGISAESGIQTFRAA-GLWADHPIEDVATPEGWARDPQRVLSFYDARRDQV-
-RGARPNAAHRALANLEAR--FEVSIVTQNIDDLHERAG--RVLHLHGEIMMARS--VDMRYPL-G----IDVCDR-GS--QLRPDVVWFGEAVP---DA
CEIVAEADLLLVVGTSLAVMPAAALINELPF-DADCVLVDPDE-LRVPAG-ARLVMPAGEGVPALTRHWQRE-------
>tr|W1N920|W1N920_9GAMM NAD-dependent deacylase OS=Halomonas huangheensis GN=AR456_16475 PE=3 SV=1
------------------------------------THKPPHLVVLTGAGISAESGIQTFRAH-GLWADHRIEDVATPEAWTRDPARVLSFYDARRDQV-
-RAARPNAAHRALANLEAR--FEVNIITQNIDDLHERAG--NVLHLHGEIMMARS--VNMRYPL-G----IDVCDQ-GS--QLRPDVVWFGEAVP---EA
CEIVAEADLLLVVGTSLAVMPAAALVNELSL-DAECILVDPDE-LQAPPG-VRWVTAAGEGVPALVRQWQRD-------
>tr|Q1QTH0|Q1QTH0_CHRSD Silent information regulator protein Sir2 OS=Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB 13768) GN=Csal
------------------------------------EHQGPHLVVLTGAGISAESGLKTFRDG-GLWENHRVQDVATPEAFARDPETVLRFYDARREQT-
-RQATPNAAHRALAELEQA--FQVSVITQNIDDLHERAG--DVLHLHGEILMSRS--ADLRYPV-G----IDLCDK-GS--QLRPDVVWFGEPVP---QA
CEIVAEADLVLVVGTSLAVMPAAMLLDQAPI-EAPCLLVDPQA-SLVPRG-RAISQLASQGVPPLVEHWRQA-------
>tr|S2LB79|S2LB79_9GAMM Uncharacterized protein OS=Halomonas anticariensis FP35 = DSM 16096 GN=L861_20075 PE=3 SV=1
------------------------------------RQRTPHLVVLTGAGISAESGLKTFRAS-GLWEEHRVEDVATPEAWVRDPGLVLRFYNQRRAQV-
-RRARPNAAHKALAELERD--FRVSIITQNIDDLHERAG--DVLHLHGEILMARS--VDMCYPV-H----IDVCDK-GS--QLRPDVVWFGEAVP---DA
CEIVEQADLLLVVGTSLAVMPAGALLRQVPM-DVDVILVDPDA-RLAPPG-AKIGQPAGEGVPELVRHWQRQ-------
>tr|U7P8P8|U7P8P8_9GAMM Uncharacterized protein OS=Halomonas sp. PBN3 GN=Q671_14005 PE=3 SV=1
------------------------------------PQRAPHLVVLTGAGISAESGIQTFRAD-GLWADHRVEEVATPEAWRRDPARVLAFYNARRDQV-
-RRARPNAAHKALAALERQ--FWVSIVTQNIDDLHERAG--QVLHLHGEILKARS--VDMHYPL-P----IDICDK-GS--QLRPDVVWFGEEVP---EA
CEIVGGADLVLVVGTSLAVMPAASLLQHAPL-GAPCVLVDPEA-ALAPPG-ARLSQPAGKGVPALVRHWRRE-------
>tr|E1V6C1|E1V6C1_HALED NAD-dependent deacetylase OS=Halomonas elongata (strain ATCC 33173 / DSM 2581 / NBRC 15536 / NCIMB 2198 / 1H9) GN=npdA PE=3 SV=
------------------------------------ETSRPHLVVLTGAGISAESGIQTFRAA-GLWADHPIEEVATPEAWARDPERVLRFYDARRDQV-
-RRARPNAAHKALAQLERE--FRVSIITQNIDDLHERAG--QVVHLHGEILKARS--VDMRYPL-P----IDVCDK-GS--QLRPDVVWFGEAVP---DA
LELVAEADLLLVVGTSLAVMPAASLLDEAPL-ATPRVLVDPEA-ELTTAG-NGLALPAGEGVPLLTRHWRRE-------
>tr|A0A098RJS5|A0A098RJS5_9GAMM NAD-dependent protein deacetylase OS=Halomonas salina GN=FP66_01440 PE=3 SV=1
------------------------------------DDSRPHLVVLTGAGISAESGIQTFRAA-GLWADEPVEAVATPEGWARDPERVLRFYDARRDQV-
-RGARPNAAHRALAELEAD--FRVSVVTQNIDDLHERAG--SVLHLHGEILMARS--VDLRYPL-S----IDVCDK-GA--QLRPDVVWFGEAVP---EA
CDIVAEADLLLVVGTSLAVMPAAMLLDQAPF-GAPCALVDPEA-ALAPAG-AKIARPAGEGVPALVRHWRET-------
>tr|W7PNP5|W7PNP5_9GAMM NAD-dependent deacetylase OS=Halomonas sp. BC04 GN=Q427_30875 PE=3 SV=1
------------------------------------EERRPHLVVFTGSGISAESGIQTFRAS-GLWADHPIEQVATPEAWRRDPRRVLEFYNIRRAQV-
-RRARPNAAHKALAELEKK--FRVSIITQNIDDLHERAG--NVLHLHGEILKARS--VDMQYRL-P----IDICDK-GS--QLRPDVVWFGESVP---EA
CEIVGEADLLLVVGTSLAVMPAASLLEHAPL-DAPCVLVDPDA-RLSPPG-ARFCQPAGKGVPQLVRQWKRE-------
>tr|A0A0P7DRZ1|A0A0P7DRZ1_9GAMM NAD-dependent protein deacetylase OS=Cobetia sp. UCD-24C GN=AOG28_14045 PE=4 SV=1
------------------------------------ARHGRHLVVLSGAGISAESGLRTFRAE-GLWEEHRLEDIATPQAFRRDPQQVLRFYDDRRTQV-
-RRARPNAAHKALAELEQH--FRVSVITQNIDDLHERAG--EVVHLHGEILKARS--VDLRYPL-P----IDLCDK-GS--QLRPDVVWFGEAVP---VA
EEIAAEADLLLIVGTSLKVMPASNLYAAAPL-DAPIVLVDPNA-ELAEPG-LPLAESAGQAVPRLVRHWLYQ-------
>tr|A0A021W4T3|A0A021W4T3_9GAMM NAD-dependent deacetylase OS=Lysobacter capsici AZ78 GN=AZ78_09985 PE=4 SV=1
--------------------------------------MKDKIVVFTGAGVSAESGLKTFRDM-GLWHEHRLEDVASPQGWQRDPATVLRFYNERRRGV-
-LAARPNAAHEAIARLEE---YEVVVITQNIDDLHERAG--NVLHVHGEILKSRST-LTRIYTL-K----IDLCER-GS--QLRPDVVWFGEAVR---EA
EAHFATAAKVLAIGTSLTVYPAAGLVDCAPL-SAERVFVSPEV-Q-VPRH-RFLQGTAAETVPPLVQRWLSH-------
>tr|A0A075P216|A0A075P216_9ALTE NAD-dependent deacetylase OS=Alteromonas australica GN=EP13_10240 PE=3 SV=1
------------------------------------MDNLPRVVVLTGAGVSAESGINTFRDSNGLWENHRVEDVATPEGFERNPALVYRFYNARRAQLH
SEEVVPNAAHMALAQLERAL--NLMLVTQNVDNLHERGG-QRVLHMHGELLSARCLYSEQRFAWSKSFDAHPCCGR-F---SLRPDIVWFGEVPMYMDTI
FDALSKADIFIAVGTSGQVYPAAGFVQTAKEYGAHTIEVNLAPTSTNLYFDESLTGKASQTVPLLVDRIIKQ-------
>tr|K6XSV5|K6XSV5_9ALTE NAD-dependent deacetylase OS=Aliiglaciecola lipolytica E3 GN=npdA PE=3 SV=1
--------------------------------------KSSKVVVLTGAGISAESGLKTFRDNNGLWENHRVEDVATPEAFERNPDVVYRFYNQRRAQLQ
SPDVKPNAGHYALAKLEEYL--NFLLITQNVDNLHERAG-KRVLHMHGELLSHRCLSSQIVKSTTEDYDEKDCCDNPS---MIRPNIVWFGEMPMFMDEI
SEALANADIFISAGTSGNVYPAAGFVQQAGLYGAHCVELNLEPSQGFSAFSESHYGPATQVIPNFIESLIK--------
>tr|A0A074KH70|A0A074KH70_9RHOB Uncharacterized protein OS=Thioclava sp. DT23-4 GN=DT23_11420 PE=3 SV=1
---------------------------------------MSRIVILTGAGISAESGIRTFRA-DGLWEEHRIEDVATPEGFSRDPALVHEFYNARRAAAR
A--AQPNAAHLALAKLEADP-HDVLIVTQNVDDLHERAGSQNVIHMHGSLFGALCHACGHRWPAPEVMS-TPACGRA----ATRPDIVWFGEMPYQMERI
VAALEDADLFVSIGTSGNVYPAAGFVQGAAEAGVETLELNLEPSTGTRLFDTAHHGPATQIVPQWVRERLTR-------
>tr|A1BAE0|A1BAE0_PARDP Silent information regulator protein Sir2 OS=Paracoccus denitrificans (strain Pd 1222) GN=Pden_4420 PE=3 SV=1
----------------------------------------MRITVLTGAGISAESGIRTFRATDGLWESHRIEDVATPQGFQRDPALVHRFYNQRRADAA
R--AQPNLAHRALARLA--EHHRVTLVTQNVDDLHERGGSPEVIHMHGSLLGALCAGCGHRWPAALVMRALPSCGKP----QTRPDIVWFGEIPYHMERI
WEAVEQADLFAAIGTSGLVYPAAGLAQHARRNGAETVELNLAASAVSRDFTDRRTGPATEVVPQWVAALCN--------
>tr|A0A099FL59|A0A099FL59_PARVE NAD-dependent deacetylase OS=Paracoccus versutus GN=IT40_09170 PE=3 SV=1
----------------------------------------MRITVLTGAGISAESGIRTFRATDGLWEEHRIEDVATPEGFRRDPALVHRFYNQRRADAA
R--ARPNAAHRALARLA--QRHELTLVTQNVDDLHERGGSPEVIHMHGSLLGALCAGCGHRWPAALVMRPPPACGQA----LARPDIVWFGEIPYHMERI
WQAVESAELFAAIGTSGLVYPAAGLAQHARRNGAETIELNLASSAVSRDFSDRRTGPATLMVPQWVDALCG--------
>tr|A0A099EZQ8|A0A099EZQ8_9RHOB NAD-dependent deacetylase OS=Paracoccus halophilus GN=IT41_13060 PE=3 SV=1
---------------------------------------MMRITVLTGAGISAESGIRTFRAADGLWEEHRIEDVATPEGFRRDPVLVHRFYNQRRADAA
R--AQPNAAHKALARLA--KSHDVTLITQNVDDLHERGGSPEVIHMHGSLLGALCANCGHRWPATLVMRSLPNCGKP----ATRPDIVWFGEIPYHMERI
WAAVENTDIFAAIGTSGQVYPAAGLAQHARRNGAETIEMNLTPSAVSSDFLQHLTGPATQVVPAWVDRLCD--------
>tr|A0A0L1JTS4|A0A0L1JTS4_9RHOB NAD-dependent deacetylase OS=Aestuariivita atlantica GN=ATO11_00545 PE=3 SV=1
---------------------------------------MQRIVVLTGAGVSAESGLSTFRGGGGLWDDHRVEDVATPEAFARDPALVHRFYNERRRKAG
A--ARPNAAHHALAELAARDDIHLTLVTQNVDGLHEAAGARDVIHMHGALADALCAACGHRWPAPKVMAAEPDCAMR----ATRPDIVWFGEIPYHMERI
AEALERADIFASIGTSGRVYPAAGFVDHAAARGVTCHGFNLDADEIGPVFDHHHVGPATQTVPAWVATLTS--------
>tr|A0A099FDZ9|A0A099FDZ9_9RHOB NAD-dependent deacetylase OS=Paracoccus sphaerophysae GN=IC63_05355 PE=3 SV=1
-------------------------------------MTPRTIVVLTGAGLSAESGIPTFRAADGLWERHRIEDVATPEAFHRDPDLVLRFYDMRRAAAA
A--AQPNAAHHALARLS--RRPGVTLITQNVDALLDRAGAQDVIHMHGRIDGALCAACGHRWPAPPTLPRTPACGAG----AARPDIVWFGEMPYHMDRI
EAALDQADLFAAIGTSGQVYPAAGFVDVARMVGAATVELNLEPTAP-GRFDEVLTGPASRIVPAWVDSLTAS-------
>tr|A0A074U327|A0A074U327_9RHOB Uncharacterized protein OS=Thioclava dalianensis GN=DL1_05630 PE=3 SV=1
---------------------------------------MAKIVILTGAGISVESGIRTFRA-DGLWEDHRIEDVATPEGFESDPDLVHQFYNARRAAAR
A--AQPNAAHSALAALEADS-HEVLIITQNVDDLHERAGSTRVVHMHGSLFGALCHACGHRWPAPQTMA-TPECGAQ----ASRPDIVWFGEMPYRMEEI
VRGLEAADLFVSIGTSGNVYPAAGFVQEARAAGIETLELNLEPSAGTRMFTEARHGPATKIVPEWVAQISG--------
>tr|D5AR47|D5AR47_RHOCB NAD-dependent deacetylase OS=Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003) GN=npdA PE=3 SV=1
---------------------------------------MARIVILTGAGVSAESGIRTFRA-DGLWEEHRIEDVATPEGFARDPALVHRFYNQRRAAAA
A--ALPNAAHLALARLEAAG-HQLLVVTQNVDDLHERAGTQNLIHMHGTLAGALCAACGHRWPAPAEMA-QPRCLHP----ATRPDIVWFGEMPYRMEEI
WAALRAADLFVSIGTSGNVYPAAGFVADARHGGVATLELNLEPSQGTRFFDEARHGPATQVVPAWVDEMLCT-------
>tr|A0A085TZB4|A0A085TZB4_9RHOB NAD-dependent deacetylase OS=Thioclava sp. 13D2W-2 GN=DW2_05510 PE=3 SV=1
---------------------------------------MAKIVILTGAGISAESGIRTFRA-DGLWEEHRIEDVATPEGFEHDPDLVHRFYNARRAAAM
A--ATPNPAHEALAELEADP-HDLLVVTQNVDDLHERAGSQNVLHMHGSLFGALCHACEHRWPAPEVMA-SPSCGRA----ATRPDIVWFGEMPYRMEEI
WHSLRAADLFVSIGTSGNVYPAAGFVADAMHAGVPTLELNLEPSAGSRMFDEARQGPASVLVPEWVRERLGG-------
>tr|S5YX87|S5YX87_PARAH NAD-dependent deacetylase OS=Paracoccus aminophilus JCM 7686 GN=JCM7686_2780 PE=3 SV=1
----------------------------------------MRIAVLTGAGISAESGIRTFRASDGLWEDHRIEDVATPEGFARDPDLVHRFYNQRRATAA
A--AEPNAAHRALARLA--GHAQLTLITQNVDDLHERGGSEAVIHMHGTLTGALCAACDHRWQAPAVMSPSPACGKP----STRPDIVWFGEMPYRMEEI
WEAVAKADLFAAIGTSGQVYPAAGLAQHARRCGARTVELNLATSAVSRDFDDHLVGPASEIVPLWVDRLIAE-------
>tr|I1AZS7|I1AZS7_9RHOB NAD-dependent deacetylase OS=Citreicella sp. 357 GN=C357_05952 PE=3 SV=1
--------------------------------------MADKIVILTGAGISAESGLGTFRDEGGLWAQHRIEDVATPQGFARDPALAHRFYNMRRAEAA
A--AAPNAAHDALAQLQRDW-GEVVIVTQNVDGLHEKAGAR-AIHMHGTLATALCAACGHRWDSPSEMAPGPACHAP----AARPDVVWFGEMPYHMDEI
SDHLLDCEIFAAIGTSGQVYPAAGFVQEARNSGARTVEMNLRDSDTSHAFDDHLVGPASKVVPRWVAGLLNS-------
>tr|A0A0P1G9H5|A0A0P1G9H5_9RHOB NAD-dependent protein deacylase OS=Tropicibacter naphthalenivorans GN=cobB_1 PE=4 SV=1
---------------------------------------MDKIVILTGAGLSAESGLGTFRDEGGLWAQHRIEDVATPQGFARNPALVHGFYNARRAQSL
Q--ATPNAAHHALAKLQNSGKAEVILVTQNVDGLHEKAGST-AIHMHGQLDSALCAACTHRWPAPLEMDGSPHCQTP----NARPDIVWFGEIPYHMDEI
ADHLATCTLFASIGTSGQVYPAAGFVQEALYAGAETVELNLNATDISRAFHQHHIGPASQIVPDWVATLL---------
>tr|Q0FQR8|Q0FQR8_PELBH NAD-dependent deacetylase OS=Pelagibaca bermudensis (strain JCM 13377 / KCTC 12554 / HTCC2601) GN=R2601_19180 PE=3 SV=1
--------------------------------------MADKIVILTGAGISAESGLGTFRDEGGLWAKHRIEDVATPEGFARDPALVHGFYNARRVQAA
S--AVPNPAHTALARLQRDW-GEVVIVTQNVDGLHEKAGAT-AIHMHGELSGALCFACGHRWTAPPQMSPGPACAAP----TGRPDIVWFGEMPYHMDEI
EDHLLGCDLFAAIGTSGQVYPAAGFVQGAAYAGARTIELNLAESEITGAFEDHRIGPASEVVPAWVAELLD--------
>tr|D0D686|D0D686_9RHOB NAD-dependent deacetylase OS=Citreicella sp. SE45 GN=CSE45_0608 PE=3 SV=1
--------------------------------------MAGKIVVLTGAGISAESGLGTFRDEGGLWAKHRIEDVATPEGFARDPALVHRFYNARRIQAA
E--ALPNAAHEALARLQRNW-GEVVIVTQNVDGLHEKAGAT-AIHMHGELSSALCYRCGHRWPSPPEMAPGPACHAR----AGRPDIVWFGEMPYHMDEI
ADHLQSCDLFASIGTSGQVYPAAGFVQEAAYAGARTIELNLADSEISRAFEDHRVGPASRIVPQWVAELLA--------
>tr|Q1GIV9|Q1GIV9_RUEST Silent information regulator protein Sir2 OS=Ruegeria sp. (strain TM1040) GN=TM1040_0674 PE=3 SV=1
---------------------------------------MKKIVILTGAGISAESGLGTFRDKGGLWSQHRIEDVATPEGFARDPELVHRFYSARRQHAA
E--ALPNAAHDALARLEERW-GDVIIITQNVDGLHEKAGSRGVLHMHGALSGALCAACAHRWPAPLQMTPEPACDAN----TARPDVVWFGEVPYHMEQI
ASHLAEADLFVAIGTSGQVYPAAAFVQEAATYGAQTLELNLEPSEVSADFAQHRFGKASDVVPIWVEDLLRD-------
>tr|A6FMP5|A6FMP5_9RHOB Silent information regulator protein Sir2 OS=Roseobacter sp. AzwK-3b GN=RAZWK3B_09026 PE=3 SV=1
---------------------------------------MDKIVILTGAGISAESGLGTFRDEGGLWAQHRVEDVATPEGFARDPALVHRFYNARRVQAA
G--AAPNAAHHALARLEAEY-GNVLVVTQNVDGLHEAAGSRNVLHMHGALSGALCAACDHRWPAPLEMSPHPRCHAQ----AARPDIVWFGEMPYHMEEI
WAHLEEADIFAAIGTSGQVYPAAAFGQHAGRSGAHTIELNLEASANVRDFTEVRQGIASVIVPEWVDGILDR-------
>tr|A3SHU0|A3SHU0_ROSNI NAD-dependent deacetylase OS=Roseovarius nubinhibens (strain ATCC BAA-591 / DSM 15170 / ISM) GN=ISM_01490 PE=3 SV=1
---------------------------------------MEKIVILTGAGISAESGLGTFRDEGGLWAQHAIEDVATPEGFARDPDLVHRFYNARRAQAA
E--ATPNPAHLALARLAREH-GEVTLITQNVDDLHHRAGSPQVLQMHGTLMGALCAACDHRWPAPLVMQPAPACAAP----ATRPDVVWFGEIPYGAEVI
DPALNGADLFVSIGTSGQVYPAAAYAQHCRRLGARTVELNLEPSENARDFDEAHYGPASKIVPEFVETLLAG-------
>tr|A0A0P1F696|A0A0P1F696_9RHOB NAD-dependent protein deacylase OS=Thalassobius mediterraneus GN=cobB_1 PE=4 SV=1
-------------------------------------MSAEKIVILTGAGISAESGLGTFRDEDGLWAQHRIEDVATPEGFAANPQLVHDFYNARRAQSV
A--ATPNAAHQALARLEAAH-GEVLVVTQNVDGLHEAAGSKAVMHMHGALSGALCAACENRWPAPMVMAPSPVCAKP----TTRPDIVWFGEMPYDMDQI
WDHLRAADLFVAIGTSGNVYPAAAFVQDAARYGAHTVELNLEASATISDFAEARFGKASEVVPAWVAEVLGT-------
>tr|A0A0Q6FBT3|A0A0Q6FBT3_9ACTN NAD-dependent deacylase OS=Marmoricola sp. Leaf446 GN=ASG49_08700 PE=4 SV=1
----------------------------------------MRVVVLTGAGISAESGLPTFRDADGLWEGHDPMTVATPEAYDADPDLVQRFYDERRAALA
R--VEPNAAHRALARLEEHLGDDLHLVTQNVDDLHERGGSRRVHHLHGRLRAAWCTACDARHEWTTTLADRPACGSR----GLRPDVVWFGEVPHDTHLV
EQALLDCDLFVAIGTSGLVYPAAAFVHYALGCGADTLELNLEVPRV-SDFAASHRGPATRTVPAWVEELVG--------
>tr|A0A0Q7BG10|A0A0Q7BG10_9ACTN NAD-dependent deacylase OS=Nocardioides sp. Root1257 GN=ASC77_12490 PE=4 SV=1
----------------------------------------MRVVVLTGAGVSAESGVPTFRD-DGLWEGHRVEDVATPEAYEYQPSVVHRFYDARRAALA
G--VEPNDAHRALAELESVL-DDLLVVTQNIDDLHERGGSRRVLHMHGELQSALCRGCGARVAWTGELG-YPRCGVS----ELRPDVVWFGEIPYEMDRI
VAALDEADLFVSIGTSGAVYPAAGFVEHARAGGARTLELNLEPSAGSHLFDEARHGPASALVPAWVRELLR--------
>tr|A0A0Q8HY08|A0A0Q8HY08_9ACTN NAD-dependent deacylase OS=Nocardioides sp. Root682 GN=ASD84_09965 PE=4 SV=1
---------------------------------------MPQIVVLTGAGISAESGVPTFRD-DGLWEGHRVEDVATPEGFEADRATVQRFYDDRRAALK
L--VDPNPAHVALAELEDAV-DALLVVTQNIDNLHERAGSRNVIHMHGELLKALCRACQVVSPWEGTLL-EPGCGAH----DLRPDVVWFGEMPYEMDRI
TDALAEATHFVSIGTSGAVYPAAGFVQHARRHGARTLELNLDPSEGSHFFHESRQGRAGDLVPVWVREMLWS-------
>tr|A0A0Q8X2A3|A0A0Q8X2A3_9ACTN NAD-dependent deacylase OS=Nocardioides sp. Root240 GN=ASE20_08055 PE=4 SV=1
---------------------------------------MPQIVVLTGAGISAESGVPTFRD-DGLWEGHRVEDVATPEGFERDRATVQRFYDERRAALR
G--VEPNPAHRALAELEETL-DALLVVTQNIDDLHERAGSQRVVHMHGELLKALCRSCGIASPWEGTLL-EPGCGEP----DLRPDVVWFGEVPYEMDRI
TDALTEASHFVSIGTSGAVYPAAGFVQHARRHGARTLELNLEPSEGTHFFHEARHGRAGDLVPVWAREVLWT-------
>tr|A0A0Q8PYH2|A0A0Q8PYH2_9ACTN NAD-dependent deacylase OS=Nocardioides sp. Root190 GN=ASE01_04315 PE=4 SV=1
---------------------------------------MPQIVVLTGAGISAESGVPTFRD-DGLWEGHHVEDVATPEGFARDRSMVQRFYDERRAALL
N--VEPNPAHLALAELEQTM-EALLIVTQNIDDLHERAGSRNVIHMHGELLKALCQSCGSASTWDSTLL-EPLCGVH----ELRPDVVWFGEVPYEMDRI
TDALADATHFVSIGTSGAVYPAAGFVQHARRHGARTLELNLDPSEGSHFFHESRQGRAGDLVPVWTREMLWH-------
>tr|A0A0A1DKT4|A0A0A1DKT4_NOCSI NAD-dependent protein deacetylase of SIR2 family OS=Nocardioides simplex GN=KR76_02885 PE=3 SV=1
---------------------------------------MPQIVVLTGAGISAESGVPTFRD-DGLWEGHRVEDVATPEGFDRDRATVQRFYDERRAALR
T--VEPNAAHRALAELEETL-EGLLVVTQNIDDLHERAGSRNVIHMHGELLKAMCRSCGAVVPWEGTLA-EPKCGAA----DLRPDVVWFGEVPYEMDRI
SDALADAALFVSVGTSGAVYPAAGFVQHARRHGARTLELNLEPSEGSHFFHESRQGRAGELVPAWVREVFWG-------
>tr|R7Y2A8|R7Y2A8_9ACTN Silent information regulator protein Sir2 OS=Nocardioides sp. CF8 GN=CF8_0169 PE=3 SV=1
----------------------------------------MRIVVLTGAGISAESGLATFRD-DGLWEGHDPMTVATPEAFAHDPELVQRFYDERRALLS
Q--VQPNAAHVALARLEAEL-NDLYLVTQNIDDLHERGGSRRVHHMHGRLAAAWCTACDERHEWTSTLV-RPSCASS----TLRPDVVWFGEMPYDMDAI
DEALWACDLFVSIGTSGLVYPAAAFVHYAIGNGKRTLELNLAASDTSSDFHESRRGPATELVPAWVDEVLAA-------
>tr|A0A0Q9RRD4|A0A0Q9RRD4_9ACTN NAD-dependent deacylase OS=Nocardioides sp. Soil797 GN=ASG90_15570 PE=4 SV=1
----------------------------------------MNVVVLTGAGISAESGVPTFRD-DGLWEGHRIEDVATPEAYEVRPSMVQKFYDDRRVALG
D--VEPNPAHEALARLEDVL-EDLLLVTQNIDDLHERGGSRRVVHMHGELLSALCRGCNRRSPWTEGLS-FPRCGVS----ELRPDVVWFGEVPYEMDRI
QRALMSTDVFVSIGTSGAVYPAAGFVQLARACGAQTLELNLVPSEGSAFFAEARHGRASDLVPLWVDEMLAR-------
>tr|A0A0Q7ZA25|A0A0Q7ZA25_9ACTN NAD-dependent deacylase OS=Nocardioides sp. Root151 GN=ASD66_15605 PE=4 SV=1
----------------------------------------MNVVVLTGAGISAESGVPTFRD-DGLWEGHRVEDVATPEAYDARPAMVQKFYDDRRAALA
G--VEPNPAHLALARLEEVI-DNLLLVTQNIDDLHERGGSRRVLHMHGELLSALCRGCGRRSHWTDELS-FPRCGVS----ELRPDVVWFGEIPYEMDRI
QRELMAADLFVSIGTSGAVYPAAGFVQMAKACGARTLELNLVPSEGTSFFDEARHGKAGELVPVWVDEVMSR-------
>tr|A1SDC5|A1SDC5_NOCSJ Silent information regulator protein Sir2 OS=Nocardioides sp. (strain BAA-499 / JS614) GN=Noca_0265 PE=3 SV=1
--------------------------------------MVVRIVVLTGAGISAESGLPTFRD-DGLWHGHRVEEVATPEAFERVPALVHRFYDERRAALA
T--VRPNAAHEALARLEQAL-DDLLVVTQNIDDLHERSGSRQVLHMHGRLRSALCGSCAGHFDWVGDLG-APRCGRR----ELRPDVVWFGEAPYDMDRI
LGAVGRADLFVSVGTSGAVYPAAGFVQYAAGQGARTLELNLVPSEGSHLFDESRHGPASRLVPEWVAEIFDT-------
>tr|A0A0B4CH09|A0A0B4CH09_9RHOB NAD-dependent deacetylase OS=Tateyamaria sp. ANG-S1 GN=RA29_05020 PE=3 SV=1
-------------------------------------MSAPSIVILTGAGISAESGLGTFRDEGGLWAQHRIEDVATPEGFARNPQLVVDFYNARRTQAA
E--ATPNAAHEALARLQSEH-GSVTLVTQNVDALHEKGGSKTVIHMHGALNSALCGRCEHRWSAPLEMTVGPHCGAP----SARPDIVWFGEMPYEMDRI
EKALARADVFVAIGTSGNVYPAAGFVQLARHAGAHTIEMNLDPGENVGLFDDIRPGMASQTVPAWVSEVLSQ-------
>tr|A0A0N7M774|A0A0N7M774_9RHOB NAD-dependent protein deacylase OS=Thalassobius sp. CECT 5113 GN=cobB_1 PE=4 SV=1
---------------------------------------MTNIVILTGAGISAESGLGTFRDEGGLWAQHRIEDVATPEGFARNPQLVHDFYNARRAQAA
-K-AKPNAAHVALAKLEQNL-GEVLIVTQNVDSLHEKAG-KNVLHMHGALNKACCAACDLRWDAPMVMSPSAGCDTP----ATRPEVVWFGEMPFHMEEI
GLALSKADVFVSIGTSGEVYPAANFVAEADHF-AHTIELNLEPSAGASRFSECRFGPASSIVPKWVEEELNR-------
>tr|A0A0N7M1D3|A0A0N7M1D3_9RHOB NAD-dependent protein deacylase OS=Thalassobius mediterraneus GN=cobB_1 PE=4 SV=1
-------------------------------------MSADNIVILTGAGISAESGLGTFRDEGGLWAQHRIEDVATPEGFAANPQLVHDFYNARRAQSL
E--ATPNAAHVALARLEAEH-GRVSIVTQNVDGLHEAAGSKAVMHMHGALDGALCAACDHRWSAPLVMQPAPNCGQP----TTRPDIVWFGEMPYQMDQI
WQHLRDADLFVAIGTSGNVYPAAAFVQDADRYGAHTVELNLEASATISDFAEARFGKASEIVPAWVDEVLGG-------
>tr|K2II21|K2II21_9RHOB Silent information regulator protein Sir2 OS=Celeribacter baekdonensis B30 GN=B30_15386 PE=3 SV=1
--------------------------------------MAGGIFILSGAGLSAESGLRTFRAADGLWEDHRVEDVATPEAFERDPELVQRFYNMRRAQA-
-AAAMPNAAHEALAKLQAD--GPVTLVTQNVDDLLERSGAREVIHMHGSVMGALCSACDHRWAAPMEMRVSPSCGM-S---HTRPDIVWFGEIPYHMDAI
QNALENSDLFVSIGTSGMVYPAAGFSQMARQLGLKTLELNLEAS--GAMFDAVIEGPATQVVPDWVSRVLSG-------
>tr|A0A0B5DR79|A0A0B5DR79_9RHOB Silent information regulator protein Sir2 OS=Celeribacter indicus GN=P73_0869 PE=3 SV=1
--------------------------------------MRGGIFILSGAGLSAESGLRTFRAADGLWEDHRVEDVATPEAFVRDPAQVQRFYNMRRAQAA
L--AEPNAAHRALARLQAEHDRPVHLVTQNVDDLLERAGAREVIHMHGALAGALCAACGSRWPAPAAMAVGPSCGAA----RTRPDIVWFGEIPYHMDRI
EEALEESDLFVAVGTSGTVYPAAGFGRMARALGIRTLELNLEASGAR--FDEQREGPASAVVPAWVAEVLGG-------
>tr|A0A074MHJ7|A0A074MHJ7_9SPHN NAD-dependent deacetylase OS=Erythrobacter litoralis GN=EH32_00725 PE=3 SV=1
------------------------------------MAKFERIVILTGAGISAESGIDTFRD-GGLWEKHRIEDVATPEGFARDPDLVLGFYDQRREALK
G--VEPNAAHKALARLEAEFG-DLLLVTQNVDNLHERGGSRDVLHMHGELSSALCTACEMRSPWDATLS-RPVCQAP----SLRPDVVWFGEMPYRMGRI
YEALSACDLFVSIGTSGAVYPAAGFVQEALMNGAHTLELNLEPSEGSRFFTESRHGPASVLVAQWVDEVLGG-------
>tr|A0A074M5J0|A0A074M5J0_ERYLO NAD-dependent deacetylase OS=Erythrobacter longus GN=EH31_16560 PE=3 SV=1
------------------------------------MTQVSRIVILTGAGISAESGIDTFRD-GGLWEKHSIEDVATPQGFARDPDLVLGFYDARRAALA
D--VEPNAAHVALARLEREFG-QFLLVTQNVDDLHERGGSTNVCHMHGELKSALCNACETRSRWEGPML-RPVCQAP----TLRPDVVWFGEIPYQMRRI
EEAMLQCDLFVSIGTSGAVYPAAGFVQQAKRLGARTLELNLEPSEGTAIFHEARHGPATQVVPAWVDEVLGG-------
>tr|T0GBH1|T0GBH1_9SPHN NAD-dependent deacetylase OS=Sphingobium baderi LL03 GN=L485_21275 PE=3 SV=1
------------------------------------DRDIRNIVILTGAGISAESGLATFRGP-----GHRVEDVCTPEALARNPALVHRFYDERRARLD
A--VEPNPAHEALAALDVEW-GDLLLVTQNVDDLHERAGAKRLIHMHGELRSALCAACGKAVPWTTPLPP-AGCGK-P---RLRPDIVFFGEMPYEMAVI
DEALRRADLFVSVGTSGAVYPAAGFVQTARHVGAHTLELNLEPSAGSVYFDESRMGPASLLVPALVRELLT--------
>tr|A0A081RJQ4|A0A081RJQ4_SPHCR NAD-dependent protein deacylase OS=Sphingobium chlorophenolicum GN=cobB_1 PE=3 SV=1
------------------------------------MDDIRNIVILTGAGISAESGLATFRGP-----GHRVEDVCTPEALARDAALVHRFYDERRAKLS
E--VRPNAAHEALAALDAQW-GELLIVTQNVDDLHERAGAKRLIHMHGELRSALCAGCGKARRWTDVLPP-DGCGK-A---LLRPDIVFFGEMPYEMDVI
DEALRRADLFVSVGTSGAVYPAAGFVQTARHVGARTLELNLDPSVGSLYFEESRMGPASMLVPELVSELLG--------
>tr|W1RX34|W1RX34_9SPHN NAD-dependent deacetylase OS=Sphingobium sp. C100 GN=C100_21355 PE=3 SV=1
------------------------------------MTDIDNIVILTGAGISAESGLATFRGP-----GHRVEDVCTPEALARDPVLVHRFYDERRATLG
A--VAPNAAHQALAALDRAW-GDLLIVTQNVDDLHERAGATRLIHMHGELKSALCAACGKAVAWSDPLPP-DGCAR-P---ALRPDIVFFGEMPYHMDRI
EAALQQADLFVSVGTSGAVYPAAGFVQSARHYGARTLELNLEPSAGSVYFDESRLGPASLLVPALVQDLLG--------
>tr|A0A0C5XAX5|A0A0C5XAX5_9SPHN NAD-dependent deacetylase OS=Sphingobium sp. YBL2 GN=TZ53_19760 PE=3 SV=1
------------------------------------MDDIRNIVILTGAGISAESGLATFRGP-----GHRVEDVCTPEALARNAALVHRFYDERRARLD
E--VKPNAAHEALAALDAAW-GELLIVTQNVDDLHERAGAKRLVHMHGELRSALCAACGKAVPWTPALPP-DGCGR-P---ALRPDIVFFGEMPYRMNLI
DDALRRSDLFVSVGTSGAVYPAAGFVQTARHVGARTLELNLEPSAGSFYFEESRIGAASILVPELVRELLG--------
>tr|A0A0M3ARK4|A0A0M3ARK4_9SPHN NAD-dependent deacetylase OS=Sphingobium chungbukense GN=YP76_07960 PE=3 SV=1
------------------------------------MDDIRNIVVLTGAGISAESGLSTFRGS-----GHRVEDVCTPEALARNAALVHRFYDERRTKLA
E--VVPNPAHEALAALDAQW-GELLIVTQNVDDLHERAGAKRLVHMHGELQSALCAACGKAKPWKDALPP-DGCGK-P---SLRPDIVFFGEMPYEMEAI
DDALRRADLFVSVGTSGAVYPAAGFVQTARHVGARTLELNLEPSAGSFYFEESRMGPASMLVPELVWELLG--------
>tr|J2DU17|J2DU17_9SPHN NAD-dependent protein deacetylase, SIR2 family OS=Sphingobium sp. AP49 GN=PMI04_00371 PE=3 SV=1
------------------------------------KQDIRNIVILTGAGISAESGLATFRGP-----GHRVEDVCTPEALAHNPALVHRFYDERRARLA
D--VVPNAAHDALAALDRAW-GELLIVTQNVDDLHERAGARRLIHMHGELNSALCAACGNAVAWSVDLPP-DACGQ-P---RLRPDIVFFGEMPYQMDRI
DVALRAADLFVSIGTSGAVYPAAGFVQTARHAGARTLELNLDPSAGSDYFEESRLGAASLLVPDMVRTLLA--------
>tr|A0A066TD65|A0A066TD65_9GAMM NAD-dependent protein deacetylase of SIR2 family OS=Gilliamella apicola GN=GAPWKB30_1449 PE=3 SV=1
-------------------------------------MKIPKIVILTGAGISAESGLSTFRAQNGLWEGYDVNDVATYEGYIRNPTAVHDFYNMLRRKLQ
NPDVKPNAAHFALAELEQKL-DNLLIVTQNVDNLHEQAG-KNIIHMHGELLKVRNEKTGQIIDCFNDVNY----QQNK---FIRPHIVWFGEIPLQMEQI
YDALSQADYFISIGTSGNVYPAAGFVQIANQTSAKTVELNLEPSLGESLFQTKIYGPASKIVPEFIKKFI---------
>tr|X2GWF3|X2GWF3_9GAMM NAD-dependent protein deacetylase of SIR2 family OS=Gilliamella apicola GN=GAPWK_0036 PE=3 SV=1
------------------------------------MLKTPKIVILTGAGISAESGLSTFRAQNGLWEGYDVNDVATYEGYMRNPVAVHDFYNMLRRKLQ
NPEVKPNTAHFALAQLELKL-DNVLIVTQNVDNLHEQAG-KNIIHMHGELLKVRNEKTGQIIDSYYDVNY----YENK---LIRPHIVWFGEIPLQMEEI
YNAISQADYFISIGTSGNVYPAAGFVQIANQVGAKTIELNLEPSLGKNLFQTKIYGPASKVVPEFIEKFI---------
>tr|A0A080KD86|A0A080KD86_9GAMM NAD-dependent protein deacetylase, SIR2 family OS=Gilliamella apicola SCGC AB-598-I20 GN=GASC598I20_006940 PE=3 SV=1
------------------------------------MLQTPKIVILTGAGISAESGLSTFRAQNGLWEGYNVDDVATYQGYLRDPIGVHNFYNMLRNKLQ
NPEVKPNAAHFALAQLEQTL-NNVLIVTQNVDNLHEKAG-KNIIHMHGELLKVRNEKNGQILDCYQDVNY----EENK---LIRPHIVWFGEMPLQMDEI
YDALSNADYFISIGTSGNVYPAAGFVQMANQFGVKTVELNLEPSLGENLFQTKIYGPASQVVPEYIKKFI---------
>tr|C9PM15|C9PM15_9PAST Transcriptional regulator, Sir2 family OS=Pasteurella dagmatis ATCC 43325 GN=cobB PE=3 SV=1
------------------------------------MSKQPKIVVLTGAGISAESGIRTFRASDGLWENHRVEDVATPEGFARDPKLVQRFYNERRKQLF
SDDVRPNAAHIALAELEKKI-NNLLVVTQNVDNLHERAGSKNIIHMHGELLKVRCMKSGQIYDWQEDITEQQCCATPQ---TLRPHIVWFGEIPLEMEKI
QTALSECDYFISIGTSGNVYPAAGFVREALFYGAYTVELNLEPSQVRSNFAEFHYGKASEVVPNYLKQFL---------
>tr|Q21KQ1|Q21KQ1_SACD2 Silent information regulator protein Sir2 OS=Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) GN=Sde_1466 PE=3 S
------------------------------------AKDYKRIVVLTGAGVSAESGLKTFRDNNGLWENHRVEDVATPEAYARNPELVQKFYNARRSQLL
TA-AQPNKAHTALGEFEQHF--EFLLVTQNVDNLHELGG-KNLIHMHGELLKARCPVSEKVSDCTKDLTDQECCTPPN---LLRPHIVWFGEMPLAMDTI
EQALCECDLFVSIGTSGNVYPAAGFVELAASYGATTVELNLDASANSRAFDTSLQGPASELVPLFFACS----------
>tr|J8VLA7|J8VLA7_9SPHN NAD-dependent deacetylase OS=Sphingomonas sp. LH128 GN=LH128_08266 PE=3 SV=1
------------------------------------MSSIRNIVILTGAGVSAESGIDTFRD-GGLWEQHRVEDVATPEAFARDPDLVLRFYDMRREAIQ
T--KQPNAAHRALAKLDAEW-GDLLIVTQNVDDLHERAGAKPVLHMHGEHLNAWCMACDERPRWTGPLI-RPECGEA----ALRPDIVWFGEMPYRMDEI
FAALEEADLFVSIGTSGAVYPAAGFVRNARELGVETLELNLEPSQGTGWFDEARHGPASALVPAWVEEVLSR-------
>tr|A0A0N1MRG5|A0A0N1MRG5_9SPHN NAD-dependent deacetylase OS=Novosphingobium sp. ST904 GN=ADT71_19100 PE=3 SV=1
------------------------------------MKDIRNIVILTGAGVSAESGIDTFRD-GGLWEQHRVEDVATPEAFARDPDLVLRFYDMRREAIQ
T--KAPNAAHLALAKLDREW-GELLIVTQNVDDLHERAGARRVLHMHGEHLNAWCTACDLRSPWRGPLI-RPECGEA----ALRPDIVWFGEMPYRMEEI
FEALERADLFVSIGTSGAVYPAAGFVRNAREFGAATLELNLEPSQGTLWFDEARHGPATELVAAWVDEMLAA-------
>tr|F6IIP0|F6IIP0_9SPHN NAD-dependent deacetylase OS=Novosphingobium sp. PP1Y GN=PP1Y_AT33890 PE=3 SV=1
------------------------------------MNQIRNIVILTGAGVSAESGIDTFRD-GGLWEQHRVEDVATPEAFARDPELVLRFYDMRREAIQ
T--KQPNAAHHALARLDAEW-GELLIVTQNVDDLHERAGATRVLHMHGEHLNAWCTACDERSPWTGPLL-RPECGVA----ALRPDVVWFGEMPYRMEEI
FAALREADLFVSIGTSGAVYPAAGFVRNARELGAATLELNLEPSQGSSWFDESRHGPATDVVPAWVDELLTR-------
>tr|A0A0Q4G3I5|A0A0Q4G3I5_9SPHN NAD-dependent deacylase OS=Sphingomonas sp. Leaf17 GN=ASE75_02070 PE=4 SV=1
------------------------------------MRDIENIVVLTGAGISAESGLATFRG-DGLWEGHRVEDVCTPEALAANPALVHRFYDARRAALA
Q--VRPNAAHDALARLDRVW-GDLLIVTQNVDDLHERAGATRMLHMHGELLSALCAACGTRMPWAGDMHD-PACAA-P---ALRPDIVFFGEMPYQMERI
DAAIATCDLFVSIGTSGAVYPAAGFVRTARHHGAATLELNLDPSASSIYFDRTRIGPAGTLVPAWVNEMLGG-------
>tr|U2YKV8|U2YKV8_9MICO Silent information regulator protein Sir2 OS=Microbacterium sp. TS-1 GN=MTS1_00969 PE=3 SV=1
---------------------------------------MARIVVLTGAGISAESGIRTFRAVDGLWEDHRIEDVATPEGYAADPALVHAFYDERRRAVA
A--AEPNAAHLALAGLEARRPGDVLIVTQNIDDLHERAGSTRVSHIHGELGSALCEACGERMPWHGDLAGGPSCGAR----ALRPDVVWFGEAVYGLDDI
FDAVALCEQFWVIGTSGAVTPAASLVAVAAEAGARTALLNLDAHDDLRLFDDVVLGPATVTVPEWVARF----------
>tr|A0A031I7X7|A0A031I7X7_9SPHN NAD-dependent protein deacylase OS=Sphingomonas sp. RIT328 GN=cobB_1 PE=3 SV=1
--------------------------------------MTASLVILTGAGVSAESGIATFRG-GGLWEGHRVEDVCTPEALAADPLLVHRFYDARRAALA
A--VEPNAAHRALAALDAAW-GELLIVTQNVDDLHERAGTRRLLHMHGELQSALCAACGARRPWSEALPP-ETCGA-A---ALRPDIVFFGEMPYQMARI
EAALARADLFVSIGTSGAVYPAAGFVQLADAYGADTLELNLERSAGSALFAETRLGPAGTLVPAWVAEMLA--------
>tr|A0A0C9N7A6|A0A0C9N7A6_SPHPI NpdA protein OS=Sphingomonas paucimobilis NBRC 13935 GN=npdA PE=3 SV=1
------------------------------------MNRIANIVILTGAGISAESGIATFRG-GGLWEGHRVEDVCTPEALAANPELVHRFYDLRRAALE
T--VRPNPAHEALARLDREW-GDLLIVTQNVDDLHERAGTRRMLHMHGALKQALCAACGERFGWADALPP-PACAA-P---ALRPDIVFFGEIPYHMERI
EAALTQADLFVSIGTSGAVYPAAGFVRLANAYGAATLELNLDRSEGSGWFDESRLGPAATLVPQWVDEMLSR-------
>tr|A0A0D6PKY2|A0A0D6PKY2_9PROT NAD dependent deacetylase OS=Acidocella aminolytica 101 = DSM 11237 GN=Aam_092_040 PE=3 SV=1
----------------------------------------MNIVVLTGAGISAESGISTFRAADGLWEKHRIEDVASPEGFLRDPSLVHDFYNRRRAQL-
-HLVAPNPAHLALAALERAWGGNFLLLTQNVDDLHERAGSRVLLHMHGELRKLVCASCGETCHWLDDAGVEPACGA-A---AMRPDIVWFGEIPYYMDEI
VAALDEADVFCAIGTSGVVYPAAGFAAEARRNGRNCLLYEINPPTGGHVFDHVIAAPASQGVPEFLRRLGVE-------
>tr|K5ZPR2|K5ZPR2_9PROT Silent information regulator protein Sir2 OS=Acidocella sp. MX-AZ02 GN=MXAZACID_01462 PE=3 SV=1
----------------------------------------MNIVVLTGAGISADSGIATFRAADGLWENHSIEDVASPEGFLRDPALVHRFYNLRRAQL-
-NQVAPNEGHLALAALEQGWGGEFLLVTQNVDDLHERAGSRNVLHMHGQLRRLLCAECGAAGPWLNESGVEPACDA-A---AMRPDIVWFGEIPYFMDEI
LEALARADVFCAIGTSGVVYPAAGFAAEARRNGRGCVLYEINPPTGGRYFDHVIEAPASAGVPEFLRRLGL--------
>tr|A0A0Q4BPV0|A0A0Q4BPV0_9SPHN NAD-dependent deacylase OS=Novosphingobium sp. Leaf2 GN=ASE49_11390 PE=4 SV=1
------------------------------------MTDYRNIVILTGAGVSAESGIDTFRA-GGLWEQHRVEDVATPEAFARDPDLVLRFYDMRRAAIQ
T--KVPNGAHLALARLDREW-GNLLIVTQNVDDLHERAGARRVLHMHGEHLNAWCTACDTRHPWRGPLM-RPHCGAN----ALRPDIVWFGEMPYRMDDI
YAALGQADLFVSIGTSGAVYPAAGLVREARAQGTATLELNLEPSQGTRWFDEARHGPASVLVPAWVDEVLSG-------
>tr|A0A0B2BTZ9|A0A0B2BTZ9_9SPHN NAD-dependent deacetylase OS=Porphyrobacter mercurialis GN=PK98_09955 PE=3 SV=1
------------------------------------MTSSRNIVILTGAGISAESGLATFRA-DGLWEEHRVEDVATPEAFARDPVLVQRFYDMRRSAVL
A--AQPNAAHRALARLDREW-GDLLIVTQNIDDLHERAGATRVLHMHGEALSAWCMACDARHPWREPLG-NPACGMA----ALRPDIVWFGEMPYQMERI
LAAVTRADLFVSIGTSGAVYPAAGFVQAATEARAGTLELNLDRSLGSRLFDETRLGPASALVPAWVEELLAD-------
>tr|A0A0P6WHA0|A0A0P6WHA0_9SPHN NAD-dependent deacetylase OS=Erythrobacter sp. SG61-1L GN=SZ64_12060 PE=4 SV=1
------------------------------------MSDIRNIVILTGAGISAESGLRTFRA-DGLWEDHRVEDVATPEAFRRDPELVQRFYDERRAGVL
A--ARPNPAHEALARLDREW-GDLLIVTQNIDDLHERAGAQRVLHMHGEALSVWCQACDARHHWEGTLL-GPACGQV----AMRPDIVWFGEMPYRMDEI
FAAIARADLFVSIGTSGAVYPAAGFVQQAGSHRVRTLELNLEPSQGSRWFDESRLGPASVLVPEWVGEVLGG-------
>tr|A0A099GDQ3|A0A099GDQ3_9RHOB NAD-dependent deacetylase OS=Paracoccus sanguinis GN=IX55_04400 PE=3 SV=1
------------------------------------ARRPDRIVVLTGAGLSAESGIATFRDAGGLWEQHRVEDVATPEAFARDPDLVLRFYDLRRAAAA
A--VAPNPAHHALARLS--HAAGVTLITQNVDALLDRAGARDVIHMHGRLDSALCAACGHRWPAPETMPRGPACGAP----AARPDIVWFGEMPYHMDRI
EAALAEADLFAAIGTSGQVYPAAGFVDLAAAMGAETVELNLDPTAP-GRFERTIAGPAGTTVPAWVDSLIGP-------
>tr|W9BRX6|W9BRX6_9SPHN NAD-dependent deacetylase OS=Blastomonas sp. CACIA14H2 GN=Q27BB25_18880 PE=3 SV=1
------------------------------------MAKIPSIVILTGAGVSAESGIDTFRA-GGLWEQHRVEDVATPEAFARDPDLVLRFYDMRRAAIQ
T--KQPNAAHEALARLDAEW-GELLIITQNVDDLHERAGATRLLHMHGTHLTAWCLACDARPEWLGPLI-RPECGVAG---QLRPDIVWFGEMPYEMERI
YEAVGACDLFVSIGTSGAVYPAAGLVREARARGAMTLELNLEPSQGSYFFHESRHGPATKLVPEWVGEMLGQ-------
>tr|A0A0D1CP63|A0A0D1CP63_9SPHN Scaffold3, whole genome shotgun sequence OS=Novosphingobium sp. P6W GN=TQ38_06415 PE=3 SV=1
------------------------------------MSDIRKIVILTGAGVSSESGIDTFRA-GGLWEQHRVEDVATPEAFERDPDLVLRFYDMRREAIQ
T--KAPNAAHLALARLDAEW-GDLLIVTQNVDDLHERAGARRVLHMHGEHLSVWCTACDARSRWTETLI-RPECGEP----ALRPDIVWFGEMPYRMDDI
FAALEDADLFVSIGTSGAVYPAAGFVRNARELGAATLELNLEPSQGTGWVDEARHGPATQVVSDWVEEILGP-------
>tr|U2Y7K3|U2Y7K3_9SPHN NAD-dependent deacetylase OS=Novosphingobium tardaugens NBRC 16725 GN=cobB PE=3 SV=1
------------------------------------MAAIRNIVILTGAGVSAESGLETFRA-DGLWENHRVEDVATPEAFARDPELVQRFYDMRRTAIM
Q--AQPNPAHAALARLDAAW-GALLLVTQNIDDLHERAGATRVLHMHGEGLSAWCTACDARIGWSRSLL-EPSCGAT----ALRPDIVWFGEMPYRMDDI
FDALREADLFVSIGTSGAVYPAAGFVRQARECGARTLELNLEASQGSAWFHETRLGPASALVPQWVEEILVT-------
>tr|A0A0Q5DFP7|A0A0Q5DFP7_9ACTN NAD-dependent deacylase OS=Nocardioides sp. Leaf307 GN=ASF50_00645 PE=4 SV=1
-------------------------------------MAAVRIVVLTGAGISAESGVPTFRD-DGLWEGHRVEDVATPEAYVADPVLVHEFYDARRAALA
G--VVPNPAHRALARLEEAL-DDLLVVTQNIDDLHERAGSTRVLHMHGELLKAWCLACEGRHPWDGPMG-DPGCGAP----ALRPDVVWFGEIPYEMDRI
LDSLGRADLFVSIGTSGAVYPAAGFVQQAARHGVPTLELNLQPSEGTAWFREARHGPAGVLVPAWVEDLLGP-------
>tr|W0A5E5|W0A5E5_9SPHN Uncharacterized protein OS=Sphingomonas sanxanigenens DSM 19645 = NX02 GN=NX02_13350 PE=3 SV=1
------------------------------------MHDIRNIVILTGAGISAESGLATFRGP-----GHRVEDICTPQALARDARLVHDFYDARRAALA
G--VEPNPAHQALAALDAAW-GALLIVTQNVDDLHERAGAKRMLHMHGALLSALCAGCNKAVPWQGAMPP-DGCGR-P---KLRPDIVFFGEMPYEMDRI
EAALMRCDLFVSIGTSGAVYPAAGFVQTARHHGARTLELNLDPSAGSVYFHETRLGPASELVPAWVADVLGD-------
>tr|A0A0Q7R4G5|A0A0Q7R4G5_9SPHN NAD-dependent deacylase OS=Sphingomonas sp. Root50 GN=ASD39_09585 PE=4 SV=1
------------------------------------MNGIRNIVVLTGAGISAESGLDTFRG-GGLWEGHPVEDICTPEALERNRALVLDFYDQRRAALS
G--VEPNAGHLALARLDREW-GGLLIVTQNVDDLHERAGAKRMLHMHGELMSAFCEHCGRRARFGGAMLD-GGCGAAD---TLRPDIVFFGEMPYEMDRI
DAALRDADLFVSIGTSGAVYPAAGYVQQARHAGIETLELNLEPSAGSYFFHETRLGPASELVPAWVDEVLAA-------
>tr|A0A0B8PLX6|A0A0B8PLX6_9VIBR NAD-dependent protein deacetylase OS=Vibrio sp. JCM 19232 GN=JCM19232_2674 PE=3 SV=1
------------------------------------NFPYRNIVVLTGAGISAESGIKTFRAQDGLWENHRIEDVATPEGFARDPDLVQSFYNKRREKLQ
TPQVEPNPAHLALGRLEREL-GKVTVVTQNIDNLHERGGTQNIVHMHGELLKARCSGSGQVFDQTQDIKTGHCCQIPQ---QLRPHIVWFGEMPLQLDYI
YSAIQEADLFVSIGTSGVVYPAAGFVHEARLYGAHTIEINLEPSAVETEFAEKRYGRAGEEVPKLVDELLSL-------
>tr|A0A0P7A4H6|A0A0P7A4H6_9SPHN NAD-dependent deacetylase OS=Citromicrobium sp. JL1351 GN=VO58_00970 PE=4 SV=1
------------------------------------MADIRNIVILTGAGISAESGIDTFRD-GGLWEKHRIEDVATPDAFARNPALVQGFYDARRAALD
T--VEPNAAHRALARLESEWDHSLLIVTQNVDDLHERAGAKSVLHMHGRLRSALCTACRARMEWHGPLS-AEACGAP----ALRPDIVWFGEMPYEMERI
YAALAGADLFVSIGTSGAVYPAAGFVQEAAAYGARTLELNLERSEGSHWFDESRQGRAGELVPAWVDELLGG-------
>tr|A0A0F5AT51|A0A0F5AT51_9GAMM NAD-dependent deacetylase OS=Salinivibrio sp. KP-1 GN=WN56_01245 PE=3 SV=1
------------------------------------AFPYRHIVVLTGAGISAESGIRTFRDQDGLWEEHHIEDVATPEGFERNPTLVQQFYNDRRRQLQ
GE-IIPNPAHEALARLEQET-ASVLVVTQNIDNLHERAGTHNIIHMHGELLKARCSHSQQTIDWTGDIQVSHCCQMPA---PLRPHVVWFGEMPLGMGQI
HDALNQADLFVSIGTSGAVYPAAGFVHEAAMHGAHTIEINLEPSAVESEFNERRYGKASTLVPKLVEEILAL-------
>tr|A0A090R7W6|A0A090R7W6_9VIBR NAD-dependent protein deacetylase of SIR2 family OS=Vibrio sp. C7 GN=JCM19233_2510 PE=4 SV=1
-------------------------------------MKPKNIVILSGSGLSAESGMRTFRYSNGLWNEHRIEDVCTPEALERDPHLVNEFYNNLRSKM-
-VDIEPNAAHHALAKLQHE--GNCHLITQNVDNFLDMAGA-DVIHMHGELNSALCPTSGQRVEWKQDIVVETCCEIPS---QLRVDIVFFGEMPYRMTEI
QSLLAKADLFIAVGTSGKVYPAAGFVHEANHFGAETIEINLEPGDLCGEFDESRQGKATVLIPELVEQLLSE-------
>tr|A0A0J1JFK3|A0A0J1JFK3_9GAMM NAD-dependent deacetylase OS=Photobacterium aphoticum GN=ABT58_12835 PE=3 SV=1
------------------------------------LFPYRNIVILTGAGISAESGIQTFRAQDGLWEKHRIEDVATPEGYYRDPALVQNFYNQRRQQLE
SGTVFPNDAHKALARLEKEL-GKVTVVTQNIDNLHEAAGTNNIIHMHGELLKAQCSHSGQAVEWSGDISLEHCCQMPA---PMRPNVVWFGEMPIGMDRI
HDALMEADLFISIGTSGAVYPAAGFVHEAAMHGAHTIELNLEPSNVESEFAEKRYGPASVLVPQFVEELLA--------
>tr|A0A0P0D7R3|A0A0P0D7R3_9CAUL NAD-dependent deacetylase OS=Brevundimonas sp. DS20 GN=JL11_00485 PE=4 SV=1
-------------------------------------MTHRNLVVLTGAGISAESGVPTFRASDGLWCGHRVEEVATPEGYAANPALVQDFYNQRRRQLA
E--VRPNAAHVALAELAARW-GDFLLVTQNVDDLHDRAHAFELIHMHGELLKARCTRSGVVMDWAGDMAADRH-HPQG---RMRPHIVWFGEMPLQMERI
EAALAACDLFVSIGTSGAVYPAAGFVQLARYAGARTVEINLEPTQGARLFDEGVYGPATEAVPAFFRDLQT--------
>tr|V4PSQ0|V4PSQ0_9CAUL Uncharacterized protein OS=Asticcacaulis benevestitus DSM 16100 = ATCC BAA-896 GN=ABENE_10145 PE=3 SV=1
----------------------------------------MNIVILTGAGISAESGVPTFRASDGLWCGHRVEAVATPEGFEADPALVQDFYNQRRRQLA
E--VRPNAAHHALARLAAEW-GDVLLVTQNVDDLHDRAYAANLIHMHGELLKARHVDTGAVQDWHTDIPVE------S---ALRPHIVWFGEMPLAMPRI
DRALAACDLFLSIGTSGNVYPAAGFVSAARQAGAHTVELNLEPSLGHSLFQEKILGPATQVVPDYIGRLLSQ-------
>tr|V4NX20|V4NX20_9CAUL Uncharacterized protein OS=Asticcacaulis sp. AC466 GN=AEAC466_03845 PE=3 SV=1
---------------------------------------MKNIVILTGAGISAESGVPTFRASDGLWCGHRVEAVATPEGYAADPALVQDFYNQRRRQLA
E--VAPNAAHHAIARLAAA--GQVLLVTQNVDDLHDRAYDNRIIHMHGELLKARHVETGKVTDWHTDLPVD------G---ALRPHIVWFGEMPLEMDRI
ERALSECDLFLSIGTSGNVYPAAGFVSAARHAGAHTVELNLEPSLGHSLFDEKILGPATQVVPDYIDALLRS-------
>tr|F4QX06|F4QX06_BREDI NAD-dependent deacetylase OS=Brevundimonas diminuta ATCC 11568 GN=BDIM_24010 PE=3 SV=1
----------------------------------------MNLVILTGAGVSAESGVPTFRASDGLWEGHRVEAVATPEGFAADPALVQDFYNQRRRQLA
G--VQPNAAHRALADLAARW-SDFLLVTQNVDDLHDRAHMFELIHMHGELKKARCTASGIVCDWHEDLEASPH-HPRG---RLRPHIVWFGEIPLEMERI
EAALARCDLFVSIGTSGAVYPAAGFVQLARMAGARTVEINLEPTQGAGLFDEGVYGPASETVPAFFGAL----------
>tr|V4NE58|V4NE58_9CAUL NAD-dependent deacetylase OS=Asticcacaulis sp. AC402 GN=ABAC402_18830 PE=3 SV=1
--------------------------------------MVRNIVILTGAGISAESGVPTFRASDGLWCGHRVEEVATPEGFEANPALVQDFYNQRRRQLA
L--VEPNAAHHALAKLAAEW-GEVLVVTQNVDDLHDRAHADRVLHMHGELLKARQIETGQVSDWTGDMAPD------G---DVRPHIVWFGEMPLDMERI
YEALAESHLFLSIGTSGNVYPAAGFVQEARRSGATTVELNLEPSLGHSLFNEKILGPATEVVPAYVERLLNG-------
>tr|V4PRY9|V4PRY9_9CAUL NAD-dependent deacetylase OS=Asticcacaulis sp. AC460 GN=ABAC460_10015 PE=3 SV=1
------------------------------------LVSMRNIVILTGAGISAESGVPTFRASDGLWCGHRVEEVATPEGFEANPALVQDFYNQRRRQLA
E--VEPNAAHHALAKLAAEW-GEVLVVTQNVDDLHDRAHVDRVLHMHGELLKARHLETGHVSAWSGDMAAD------G---DVRPHIVWFGEMPLDMDVI
GRALGNSHLFLSIGTSGNVYPAAGFVQEARRAGAHTVELNLEPSLGHSLFDEKILGPATQVVPEYVEQLLAG-------
>tr|V4P4C4|V4P4C4_9CAUL NAD-dependent deacetylase OS=Asticcacaulis sp. YBE204 GN=AEYBE204_05720 PE=3 SV=1
--------------------------------------MRPSIVILTGAGISAESGVPTFRASDGLWCGHRVEAVATPEGFDANPVLVHDFYNQRRAQLK
D--VAPNAAHEALARLSAAY-GDVLLVTQNVDDLHDRAHRFGLIHMHGELLRARCVETGKSCDWSGDMLIDPF-G-ES---GLRPDIVWFGEMPFEMDRI
YDALSGCGLFISIGTSGNVYPAAGFVQEARRAGAHTVELNLEPSQGQSLFDEKIYGPATEVVPAFVEQLLS--------
>tr|A0A063Y420|A0A063Y420_9GAMM NAD-dependent protein deacetylase of SIR2 family OS=Nitrincola lacisaponensis GN=ADINL_1542 PE=3 SV=1
-------------------------------------MRYRQIVVLTGAGISAESGIRTFRDQNGLWEDHRIEDVASPEGFQRNPGLVYQFYNLRRQQLL
DPALEPNAAHLMLAEFEAEHRGRFTLITQNVDNLHQRAG-RHIIPMHGQLQSALCQSSGLSHPWTGELTAVRCCATPQ---PLRPDIVWFGEVPYQLDQC
FDALSVADLFVSIGTSGKVYPAAGFMDVAQQAGAVTVELNLEPTR--NDVDQGYYGPASEVVVEFFESLMEL-------
>tr|A0A0M0M3I4|A0A0M0M3I4_9GAMM NAD-dependent deacetylase OS=Rheinheimera sp. KL1 GN=WH43_13345 PE=3 SV=1
-------------------------------------MRFNNIVVLTGAGISAESGIKTFRDSNGLWENHQIEDVATPEGYQRNPALVHQFYNQRRAQLL
DPKLKPNSAHQALAQFELQK--RFLLITQNVDNLHQRAG-ESLIAMHGQLQKVKCPVTGKNLSWLKDLTAAHCCKNPQ---PLRPDIVWFGEMPYLMDDC
VDALMQADLFISIGTSGQVYPAAGFVKIAAESGAHTVELNMEAT--RGDFAEGYYGPAAKIVPAYLSKLS---------
>tr|F7NSW4|F7NSW4_9GAMM NAD-dependent protein deacetylase, SIR2 family OS=Rheinheimera sp. A13L GN=Rhein_0851 PE=3 SV=1
-------------------------------------MRFNNIVVLTGAGVSAESGIKTFRDHNGLWENHKIEDVATPEGYARDPALVQQFYNQRRAQLL
DPKLKPNAAHLALAQFELQK--NFLLITQNVDNLHQRAG-EHVIAMHGQLQKVKCPLSGKNQSWLKDVTATHCCKTPQ---PLRPDIVWFGEMPYQMDQC
ADALMQADLFLSIGTSGQVYPAAGFVQIAAQAGAHTVELNMEAT--RGDFAEGYYGLAAKIVPAYLAKLS---------
>tr|A0A099PB75|A0A099PB75_9GAMM NAD-dependent deacetylase OS=Nitrincola sp. A-D6 GN=LH51_14120 PE=3 SV=1
-------------------------------------MKFRHIVVLTGAGISAESGIRTFRDQNGLWEDHRIEDVATPEGFQRDPDLVYSFYNLRRAQLQ
DPAIEPNPAHLALAEFEASHAGQFTLITQNVDDLHRRAG-RNMIAMHGQLQSALCSRSGLSHPWIGSLSASSCCDTPQ---VLRPDIVWFGEVPYQLDDC
FNALATTDLFISIGTSGKVYPAAGFLGVAQDAGAMTVELNMEPTR--EDFDQGYYGPASQVVVEYLNRLEDQ-------
>tr|A3X4P6|A3X4P6_9RHOB NAD-dependent deacetylase OS=Roseobacter sp. MED193 GN=MED193_20614 PE=3 SV=1
------------------------------------QAMYDKVVILTGAGISAESGLGTFRDAQGLWAQHRIEDVATPAGFARNPDLVQAFYNARRAQAA
L--AQPNAAHLALAQLQSSF-GEVILVTQNVDALHEAAGSMSVLHMHGTLAGALCASCNHRWPAPPELSSNPQCQST----AARPDVVWFGEIPYHMDRI
LSDLETCDLFVAIGTSGQVYPAAGFVDAATAAGAKTIELNLEPSATHSRFDDARFGRASAIVPAWVAELLDE-------
>tr|A0A0N8FTZ8|A0A0N8FTZ8_9RHOB NAD-dependent deacetylase OS=Phaeobacter sp. 11ANDIMAR09 GN=AN476_03525 PE=4 SV=1
------------------------------------SEIYCKIVILTGAGISAESGLGTFRDAQGLWAQHRIEDVATPEGFARNPTLVQDFYNTRRHQAA
E--AQPNAAHLALARLQTNY-GQVILVTQNVDGLHEAAGAAAVLHMHGSLANALCAACDHRWTAPQVLSQDPHCGTH----AARPDVVWFGEMPYHMDQI
FSELESCDLFAAIGTSGQVYPAAGFVDAATRAGAETLELNLEPSAASSRFEAARFGPATRVVPAWVEELLPS-------
>tr|A0A0G3XLG9|A0A0G3XLG9_9SPHN NAD-dependent deacetylase OS=Croceicoccus naphthovorans GN=AB433_01880 PE=3 SV=1
------------------------------------SNGIRNIVILTGAGVSAESGIDTFRD-GGLWEQHRVEDVATPEAFVRDPDLVLRFYDMRRESIQ
T--KQPNPAHEALARLDREW-GELLIVTQNIDDLHERAGAKRVLHMHGEHLNAWCTACDVRSRWTGTLV-RPECGEP----ALRPDVVWFGEMPYQMDRI
FAAIRDADLFVSIGTSGAVYPAVGFVQNANDLGADTLELNLERSQGSHWFDETRLGPAGQIVPEWVDEILSS-------
>tr|A0A0H4V9U7|A0A0H4V9U7_9SPHN NAD-dependent deacetylase OS=Erythrobacter sp. s21-N3 GN=CP97_04130 PE=3 SV=1
--------------------------------------MLQNIVILTGAGISAESGLKTFRA-DGLWENHPVEEVATPEGFARDPDLVQRFYDERRMRVL
A--AQPNPAHEALGRLEREL-DRLLIVTQNIDDLHERGGAGRVLHMHGEVLSAWCQRCDARHRWERSLR-GPSCEMV----SLRPDIVWFGEMPYQMGRI
FGALEQADLFVSIGTSGAVYPAAAFVQHARDARARTLELNLERSAGSALFDETRLGPASKLVPQFVQDMLAA-------
>tr|A0A0G9MKL1|A0A0G9MKL1_9SPHN NAD-dependent deacetylase OS=Erythrobacter gangjinensis GN=AAW01_13025 PE=3 SV=1
---------------------------------------MVNIVILTGAGISAESGLKTFRA-DGLWENHPVEQVATPEGFARDPDLVQRFYDERRAQIR
A--AAPNAAHKALGRLEREF-GNLLLVTQNIDDLHERGGATQTLHMHGEALSAWCLSCDTRHSWSTTLR-SPSCGDA----ALRPDIVWFGEMPYQMDRI
FDALSRADLFVSIGTSGAVYPAAGFVQQASANGARTLELNLERSAGSHLFDETRLGPASELVPTWVDEMLAG-------
>tr|A0A0B1ZLR6|A0A0B1ZLR6_9SPHN NAD-dependent deacetylase OS=Novosphingobium malaysiense GN=LK12_16345 PE=3 SV=1
------------------------------------MSTIRNIVILTGAGVSAESGIDTFRD-GGLWEQHRVEDVATPEAFARDPELVQRFYDMRREAIQ
T--KQPNAAHHALARLDSEW-GNLLIVTQNVDDLHERAGAKRVLHMHGEHLNAWCTACDVRSRWTGPLI-GPACGER----ALRPDVVWFGEIPYRMEEI
FAALQEADLFVSIGTSGAVYPAAGFVRNARDLGVATLELNLEPSQGTLWFDEARHGPASEVVPAWVDEMLS--------
>tr|A0A0F7KSY0|A0A0F7KSY0_9SPHN NAD-dependent protein deacylase OS=Altererythrobacter atlanticus GN=cobB PE=3 SV=1
------------------------------------MANIRNIVILTGAGISAESGLRTFRA-DGLWEDHRVEDVATPEAFIRDPDLVQRFYDARRAGVQ
E--AQPNPAHEALARLDSQW-DELLIVTQNIDDLHERAGAGRVLHMHGEALSAWCTACNARHRWLATLA-GPSCGTA----AMRPDIVWFGEMPYRMEEI
FAALARADLFVSIGTSGAVYPAAGFVQQAGAHGARTMELNLDRSQGSHWFDDTRLGPASVLVPQWVDDLLGG-------
>tr|Q2N7Y3|Q2N7Y3_ERYLH Putative NAD-dependent protein deacetylase OS=Erythrobacter litoralis (strain HTCC2594) GN=ELI_10580 PE=3 SV=1
------------------------------------TQEIRNIVILTGAGISAESGIDTFRS-GGLWEQHNVEDVATPEGFTRSPELVLNFYDMRREALG
K--VQPNPAHDALARLDAEFG-ELLIVTQNVDDLHERAGAKRVLHMHGELKSALCLACEMRSPWDATLS-RPVCQAP----SLRPDVVWFGEMPYQMDRI
YRAIREADLFVSIGTSGAVYPAAGFVQDARNLGVQTLELNLERSEGSHWFHESRLGSAGELVPEWVGEVLG--------
>tr|A0A0H0XW03|A0A0H0XW03_9SPHN NAD-dependent deacetylase OS=Erythrobacter marinus GN=AAV99_02355 PE=3 SV=1
------------------------------------MATFRNIVVLTGAGISAESGLKTFRA-DGLWEDHPVEEVATPEGFARDPDLVQRFYDERRAQVL
A--AQPNAAHEALGRLDREF-GELLIVTQNFDDLHTRGGAERVLHMHGEALSAWCTACDARHPWRGTLR-GPSCGAA----AMRPDIVWFGEMPYQMDRI
FASLSAADLFVSIGTSGAVYPAAGFVQAASDTGSRTLELNLERSAGSHRFDETRLGPASELVPEWVDAVLGE-------
>tr|G2I2U2|G2I2U2_KOMMN NAD-dependent deacetylase OS=Komagataeibacter medellinensis (strain NBRC 3288 / BCRC 11682 / LMG 1693 / Kondo 51) GN=GLX_26590 
---------------------------------------MQHIVVLTGAGISQESGLQTFRGADGLWNHERIEDICTPEGFRRDPLRVDCFYNGLRAQL-
-PGVQPNAAHHALARLEQAAQGEITIITQNIDDLHERAGSHNVIHMHGELLRLLCTHCRATPHWHTDCYPDPHCGQ-P---ALRPDIVWFGEMPYHMDTI
ARHLAACDLFVAIGTSGIVYPAAGFVESV-TDHADTMLFNLEVPQEPSAFEQIILGPATRTIPNWTRAVLAA-------
>tr|A0A0G9MVS1|A0A0G9MVS1_9SPHN NAD-dependent deacetylase OS=Erythrobacter sp. KA37 GN=AAW00_06945 PE=3 SV=1
------------------------------------MSAIRNIVILTGAGISAESGIRTFRA-DGLWEDHPVEQVATPEGFARDPGLVQRFYDQRRADIR
A--ARPNAAHLALGRLDEAW-GNLLIVTQNIDDLHERGHARRVLHMHGEGLSAWCTACDMRHRWEGTLR-GPACCEK----ALRPDIVWFGEMPYQMERI
YTAIAAADLFVSIGTSGAVYPAAGFVEQARRSGARTLELNLERSLGSMMFDETRLGPASELVPAFVVDLLRA-------
>tr|A0A074MLA6|A0A074MLA6_9SPHN NAD-dependent deacetylase OS=Erythrobacter sp. JL475 GN=EH30_11500 PE=3 SV=1
------------------------------------ADRPSSIVILTGAGISAESGIDTFRS-GGLWEQHRVEDVATPEGFARNPDLVLGFYDARRKALG
R--AEPNPAHVALARLEREFG-ELLLVTQNVDDLHERGGSARVLHMHGELKSALCTSCEMRSRWDAAMI-RPVCAAP----TLRPDVVWFGEMPYQMGRI
YRALESCDLFVSIGTSGAVYPAAGFVQEARANGAATLELNLEPSEGSHFFSESRHGLAGELVPQWVAEVLGA-------
>tr|A0A0G3X3M1|A0A0G3X3M1_9SPHN NAD-dependent protein deacylase OS=Altererythrobacter marensis GN=AM2010_4 PE=3 SV=1
------------------------------------MADIRNIVILTGAGVSAESGIDTFRG-GGLWEQHRVEDVATPEAFARDPDLVLRFYDMRRAAIQ
E--KEPNPAHAALARLDAEW-GELLIVTQNVDDLHERAGARRVLHMHGTHLNAWCAACDARSRWTGPLI-RPACDAQ----ALRPDVVWFGEMPYGMERI
YGALRSADLFVSVGTSGAVYPAAGFVRDARELGTQTLELNLERSQGSTWFDETRLGPASELVPAWVDEMLG--------
>tr|A0A0J7XTH3|A0A0J7XTH3_9SPHN NAD-dependent deacetylase OS=Novosphingobium barchaimii LL02 GN=V474_21655 PE=3 SV=1
------------------------------------MATIPNIVILTGAGISAESGIDTFRS-GGLWESYAVEDVATPEAFERDPDLVLGFYDMRREAIQ
T--KTPNAAHMALARLDREW-KDLLIVTQNLDDLHERAGASRVLHMHGEHLSVWCTACDARSRWKETLI-RPECGEP----ALRPDIVWFGEMPYRMDEI
FEALHEADLFVSIGTSGAVYPAAGFVRNARELGAATLELNLEPSQGTGWFDEARHGPATQIVSQWVEEMLNP-------
>tr|J3AMI9|J3AMI9_9SPHN NAD-dependent protein deacetylase, SIR2 family OS=Novosphingobium sp. AP12 GN=PMI02_00805 PE=3 SV=1
------------------------------------MTSIRNIVILTGAGISAESGIDTFRS-GGLWEQHRVEDVATPEAFERDPDLVLRFYDMRREAIQ
T--KEPNAAHHALAKLDAEW-GELLIVTQNVDDLHERAGARRVLHMHGEHLNAWCTACDVRSPWTGTLI-RPECGEA----ALRPDVVWFGEMPYQMDEI
FAALRGADLFVSIGTSGAVYPAAGFVRNARELGAETLELNLEPSQGTAWFDEARHGPATRIVQAWVEEMLSL-------
>tr|A0A0N1AZ44|A0A0N1AZ44_9SPHN NAD-dependent deacetylase OS=Porphyrobacter sp. AAP60 GN=IP79_12170 PE=3 SV=1
------------------------------------NARYRRIVILTGAGISAESGIDTFRA-GGLWEQHRIEDVATPEGFARDPNLVLNFYDLRRAALA
N--VAPNPSHMALALLEREFG-DLLLVTQNVDDLHERGGSARVLHMHGELKSALCTSCETRSPWLETMI-RPVCRAP----TLRPDVVWFGEMPYQMGRI
YQALETCDLFVSIGTSGAVYPAAGFVQEARAAGARTLELNLEPSEGSRLFHETRHGPASVLVPEWVEEVLQT-------
>tr|M5U0K2|M5U0K2_9PLAN Silent information regulator protein Sir2 OS=Rhodopirellula sallentina SM41 GN=RSSM_03788 PE=3 SV=1
----------------------------------------MNILILTGAGISAESGIPTFRDANGLWEGHHVEEVATPQGFERNPSLVHRFYNERRRALL
SPEIQPNAAHIALAEFEKRHKGDFLIVTQNIDDLHVRAGSRNVLPMHGELLKVRCVHSHKTFDWNEDLDLTEDESRRG---CLRPHVVWFGELPIGLEQI
GEAAAKADVFIAIGTSGLVYPAAGIVQQTQP-TCRKIEINLGDTPASNAFNECRHGKAGEQVPRLLAELE---------
>tr|M5TC69|M5TC69_9PLAN Silent information regulator protein Sir2 OS=Rhodopirellula sp. SWK7 GN=RRSWK_00846 PE=3 SV=1
----------------------------------------MNILVLTGAGISAESGIPTFRDANGLWEGHAVEEVATPQGFASNPVLVHQFYNERRRALR
SAEIRPNAAHIALAEFEQKHVGDFLIVTQNIDDLHFRAGSRNVLPMHGELFKVRCLYSNKIFDWKDDLSTTDNEELRG---CLRPHVVWFGEVPIGLDRI
ENAASNADVFIAVGTSGLVYPAAGIVQLTKP-TCRKIEVNLGGTPASDAFDECRHGKAGEILPQLLAEIE---------
>tr|K5D9G1|K5D9G1_RHOBT Silent information regulator protein Sir2 OS=Rhodopirellula baltica SH28 GN=RBSH_05564 PE=3 SV=1
----------------------------------------MNVLILTGAGISAESGIPTFRDANGLWEGHAVEEVATPQGFARNPNLVHEFYNQRRRALL
NPEIQPNAAHVALTDFEREHEGDFLLVTQNIDNLHQRAGSQNVLAMHGQLLQVRCVYSEEIFDWTGDLSVTEDDSMRG---CLRPNVVWFGEMPIGLTQI
EKAATKADLFIAIGTSGVVYPAAGIVAQTPP-HCRRIEVNLDDTPASSAFDETIRGAASVEIPKLLNHFSAM-------
>tr|A0A0H3T8Z0|A0A0H3T8Z0_9GAMM NAD-dependent deacetylase OS=Photobacterium kishitanii GN=UA38_04390 PE=3 SV=1
------------------------------------LFPYKNIVVLTGAGISAESGIRTFRAADGLWEEHRVEDVATPEGYQRDPELVQAFYNARRAQIE
NGSVTPNAAHYALAKLEAEL-GTVTIVTQNIDNLHERAGSHNVIHMHGELLKVRCCESGQTLEWHGDLHTSHCCQIAA---PLRPDIVWFGEMPIDMDKI
HDAIVKADLFIAIGTSGNVYPAAGFVHEASLQGAHTIELNLEPSNVENEFEEKRYGKASELVPAYVDELLKA-------
>tr|D0YXV7|D0YXV7_PHODD NAD-dependent protein deacetylase of SIR2 family OS=Photobacterium damselae subsp. damselae CIP 102761 GN=VDA_002120 PE=3 SV=1
------------------------------------LFPYRNIVVLTGAGISAESGICTFRSEDGLWENHRVEDVATPEGYERNPELVQNFYNDRRRQIE
DGSVAPNAAHLALAQLEREH-GKVTIVTQNIDNLHERAGSVNVIHMHGELLKARCCESGQTVDWHGDLHTSHCCQIPA---PMRPDIVWFGEMPIGMDAI
HRAICDADLFISIGTSGVVYPAAGFVHEAVLQGLHTVELNLEPSQVQSEFEEKIYGKATQIVPEYIKNTLSI-------
>tr|F2P828|F2P828_PHOLD Protein deacetylase, Sir2 homolog OS=Photobacterium leiognathi subsp. mandapamensis svers.1.1. GN=cobB PE=3 SV=1
------------------------------------LFPYKNIVVLTGAGISAESGIRTFRSEDGLWEEHRVEDVATPEGYHRDPELVQRFYNARRAQIE
NGTIEPNTAHIALAKLEQEL-GNVTIVTQNIDNLHERAGSKNVIHMHGELLKARCCESGQKVEWHGDLNTSHCCQIPA---PMRPDIVWFGEMPIGMDRI
HDAIVQADLFISIGTSGNVYPAAGFVHEAALQGAHTIELNLEPSNVENEFEEKRYGKASELVPAYVEELLSA-------
>tr|A0A0A3AN06|A0A0A3AN06_9PAST NAD-dependent deacetylase OS=Chelonobacter oris GN=OA57_04740 PE=3 SV=1
------------------------------------KRTLPNIVILTGAGISAESGIRTFRAADGLWENHRIEDVATPEGFRRNPELVRQFYNQRRRQLQ
QAEIQPNAAHYALAELERFF-ENVLLVTQNVDNLHERAG-KNLIHLHGELLKVRCVHCGSVVRWHSDITANKTCG--G---GLRPHIVWFGEMPFETERI
YTALQQCDYFLSIGTSGNVYPAAGFVEEANFA-AVTVELNLEPSKSGTAFKETDYGPASQVVPAYCRKLIGL-------
>tr|A0A0K0HK48|A0A0K0HK48_PASMD NAD-dependent deacetylase OS=Pasteurella multocida GN=GJ37_09210 PE=3 SV=1
------------------------------------MTKQVRIVVLTGAGISAESGIRTFRATDGLWENHPVDEVATPEGFARNPKLVQRFYNERRKQLF
SDQIAPNVAHFALAELEKKL-DNLLIVTQNVDNLHERAGSKNLIHMHGELLKVRCVKSGKIYDWQGDIGEHLCCTPTQ---ILRPHIVWFGEMPLEMEKI
QTALSECDYFISIGTSGNVYPAAGFVREALFYGAHTVELNLEPSQVRSSFDECHYGKATELVPHYLAQFL---------
>tr|A0A095TL36|A0A095TL36_9GAMM NAD-dependent deacetylase OS=Alcanivorax jadensis T9 GN=T9A_00478 PE=3 SV=1
--------------------------------------MAENIVILTGAGISAESGIKTFRAADGLWENHRVEDVATPEAFLRDATLVQTFYNKRREQLL
SGAIKPNAAHQALAKLEQAF-GQVLLVTQNIDNLHERAGSRNLIHMHGELLKGRCQASGGLVEVTGELTPTPLCGAKG---CLRPHVVWFGEMPLEMERI
YQALASCDRFISIGTSGNVYPAAGFVEEANRHGAHTVELNLEPSQRLTAFAEHKHGLATELVPAYVEALITS-------
>tr|B7RLC9|B7RLC9_9RHOB NAD-dependent deacetylase OS=Roseobacter sp. GAI101 GN=npdA PE=3 SV=1
---------------------------------------MSKIVILTGAGISAESGIETFRAEDGLWAQHRVEDVATPEGFARNPELVVSFYNARRKQAA
E--VSPNAAHKALARLEQLY-GQVIVVTQNVDDLHEKGGSQNVMHMHGALKSALCAACDHRWPAPMVMAPGPKCSAP----AARPDIVWFGEMPYEMDAI
FDHLAEADIFAAIGTSGNVYPAAGFVAEARSNGAHTIELNLERSAVGNQFAEHRTGPATRTVTDWVDELLGA-------
>tr|A9EAQ0|A9EAQ0_9RHOB NAD-dependent deacetylase OS=Oceanibulbus indolifex HEL-45 GN=OIHEL45_00797 PE=3 SV=1
---------------------------------------MTKIVILTGAGISAESGLETFRASDGLWAQHRVEDVATPEGFARNPKLVVDFYNARRAQAA
E--VSPNAAHQALARLEAEL-GEVVVITQNVDDLHEQGGSQNVMHMHGALKGALCAACDYRWPAPMFMAPGPACNAP----AARPDIVWFGEMPYEMDTL
FQHLAEADIFAAVGTSGNVYPAAGFVAEARRAGAHTIEFNLERSAVGNQFEDHRIGPASQTIPAWVDEVLRS-------
>tr|Q169N6|Q169N6_ROSDO NAD-dependent deacetylase OS=Roseobacter denitrificans (strain ATCC 33942 / OCh 114) GN=npdA PE=3 SV=1
---------------------------------------MKKIVILTGAGISAESGLGTFRAEGGLWAEHRIEDVATPEGFARDPRLVVDFYNARRAQAA
-E-AAPNAAHLALAKLEEAF-GEVVLVTQNVDDLHEKAG-KRVMHMHGALNGALCGACDHRWPAPMVMAPGPGCEAP----AARPDIVWFGEMPYDMEEI
YDHLAQADLFAGIGTSGNVYPAAGFVAEARRS-ARTLEFNLEPSAVGSQFDNIRIGPATQTVPAWVAEILGS-------
>tr|A0A073IJT8|A0A073IJT8_9RHOB NAD-dependent deacetylase OS=Sulfitobacter donghicola DSW-25 = KCTC 12864 = JCM 14565 GN=DSW25_06145 PE=3 SV=1
---------------------------------------MPDIVILTGAGISAESGIETFRADTGLWAQHKVEDVATPEGFARNPERVVAFYNTRRAGIA
A--AEPNAAHLALAKLEAEN-GSVLIVTQNIDDLHERGGSQNVIHMHGAAGSALCASCDHRWPAPLVMHVTPSCGAA----PARPDIVWFGEIPYQMDRI
IDAISVADIFVSIGTSGNVYPAAGFVAEAARNGVATLEINLEPSAVGSQFEDAIMGPATQTVPAWVEQILNG-------
>tr|A0A0N0D8I6|A0A0N0D8I6_9RHOB NAD-dependent protein deacylase OS=Shimia sp. SK013 GN=cobB_2 PE=3 SV=1
--------------------------------------MTAKIVILTGAGISAESGLGTFRDVDGLWTKYDLNDVATPEGFARNPELVMAFYNARRANAA
E--ATPNAAHKALARLEADF-GEVFIVTQNVDGLHEAAGSRNVLHMHGALHGALCKACEHRWPAPPVMSVTPHCRKP----ATRPDVVWFGEIPYGMHVI
SEALSQADVFVSIGTSGEVYPAANFVAEADHHGAHTIELNLEPSAGASGFAETRFGPATEVVPQWVADELAR-------
>tr|A0A061STB5|A0A061STB5_9RHOB NAD-dependent deacetylase OS=Sulfitobacter mediterraneus GN=PM02_10530 PE=3 SV=1
------------------------------------TQPNAKIVILTGAGISAESGIETFRAEDGLWAQHRVEDVATPEGFARDPELVVQFYNARRAQAA
E--VHPNAAHRALARLEAEH-GEVVVITQNVDDLHERGGSDTVHHMHGHLKGALCAICDHRWPAPMVMAVGPSCNAP----AARPDIVWFGEMPYEMDLL
FDHLTQADVFAAIGTSGNVYPAAGFVAEARRAGAHTLEFNLERSAVGNQFAEHRLGPASETVTAWVAEILGR-------
>tr|A0A085BS87|A0A085BS87_9RHOB NAD-dependent deacetylase OS=Sulfitobacter sp. CB2047 GN=IV89_08630 PE=3 SV=1
---------------------------------------MSKIVILTGAGISAESGIDTFRAEDGLWAQHRVEDVATPEGFARDPQLVVDFYNGRRKQAA
K--VSPNAAHQALARLQANY-GQVVIVTQNVDDLHEQGGA-RVIHMHGALNSALCAACDHRWPAPIVMAVGPACNAA----AARPDIVWFGEMPYDMDEI
FDHLAEADIFAAIGTSGNVYPAAGFVAEARRNGAHTVELNLERSAVGNQFAEHRTGPATRVVTDWVEQLLAT-------
>tr|A0A0F9MYN0|A0A0F9MYN0_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_1033340 PE=3 SV=1
---------------------------------------MSKIVILTGAGISAESGIETFRAEDGLWAQHRVEDVATPEGFARDPAMVVNFYNARRKQAA
N--ATPNAAHKALAKLQQLY-GQVVIITQNVDDLHERGGSRDVLHMHGALNSALCVACEHRWPAAMTMAPGPKCSAP----AARPDIVWFGEMPYDIDAI
FDHLAQASIFAAIGTSGNVYPAAGFVAEAHRTGAHTVELNLERSAVGGQFAEHRTGPATRVVSEWVEELLAK-------
>tr|R9PK62|R9PK62_AGAAL NAD-dependent protein deacetylase of SIR2 family OS=Agarivorans albus MKT 106 GN=AALB_1810 PE=3 SV=1
--------------------------------------MKKNVIVLTGAGVSAESGIQTFRDSDGLWEKHRVEDVATPEAYQRSPDFVDQFYNLRRKQLQ
DGNVHPNPAHFALAELEKHQ--ELLVITQNIDDLHERAG-KNVLHMHGELLKARCPVSNQTTVWKEDLGSDTCCQFPT---RLRPHVVWFGEMPIGLDRI
YHQLNHCDIFMAIGTSGHVFPAGGFVHEAASHDARTIELNLEPSEMQSEFGERYYGPASELVPEFLSELTSE-------
>tr|B6BL85|B6BL85_SULGG NAD-dependent deacetylase OS=Sulfurimonas gotlandica (strain DSM 19862 / JCM 16533 / GD1) GN=npdA PE=4 SV=1
---------------------------------------MSKVLILSGAGISAESGISTFRDSDGLWEKHRIEDVCSAGCLDTNGEATIKFYDARRADI-
-KDKTPNYAHKVIAELKQKY-NEISVLTQNIDDMFEKAG-NEIVHLHGFIRELRCRDCDEIFDI-------TQCPSCGG--SLRPNIVFFGEAAYKLTQ-
--ELNRCELIVIIGTSGNVLDVTYFAQL-----DKSILNNLEN-IDDSYFTKVYYAKATEAIGEISEYIEEF-------
>tr|A0A0F3IJQ0|A0A0F3IJQ0_9GAMM NAD-dependent deacetylase OS=Methylococcaceae bacterium Sn10-6 GN=VZ94_09325 PE=3 SV=1
------------------------------------LKPTDFIVILTGAGISAESGIRTFRAQDGLWEEHRIEDVATPEGFMRNPELVHAFYNQRRRQLQ
EASVMPNPAHLALTRLEQQWP--VLIITQNVDNLHERAG-QKLLHMHGELNKIFCQFCKTRLIWNTDLSTEPHCGNVG---MLRPDIVWFGETPYHMDEI
LRALAVCQLFISIGTSGLVYPAAKFAQIAS--QAYRIETNLQETEISGSFNKHLIGPAGSEIPKLIEALLAR-------
>tr|A5EXW2|A5EXW2_DICNV NAD-dependent deacetylase, Sir2 family OS=Dichelobacter nodosus (strain VCS1703A) GN=DNO_1032 PE=3 SV=1
-----------------------------------------MIVILTGAGISAESGIKTFRSDNGTWEEHRVEDVATPEGFMRDPELVHQFYNARRAQL-
-STVSPNAAHLALARLQKEAK--VAIITQNIDDLHERAG-D-AIHMHGELYKIRCLFCQNVFLWKTDCGPQPVCHKSG---ALRPDIVWFGEMPHHMEEI
ENMLALANIFVAIGTSGVVYPAAGFVQLAHAYGAKTIEINLNKTEGTKLFDEGIYGAATKAVPSWVEAVLA--------
>tr|K7ZBJ9|K7ZBJ9_BDEBC NAD-dependent deacetylase OS=Bdellovibrio bacteriovorus str. Tiberius GN=cobB PE=3 SV=1
------------------------------------LRLFKNIVILTGAGISAESGIRTFRDQNGLWEDHRIEDVATPEAFARNPSLVQRFYNLRRAQLK
EPNLTPNPAHQALVELENLWE--FLLVTQNVDNLHRRAG-KNLLHMHGRLDRVFCLHCDEHFEWLLDLAVDPQCGRQG---GVRPDIVWFGEMPHYMEEI
YAALDKADYFISIGTSGNVYPAAGFVRLAW--KARKIEINLKDTEISPAFDEHYVGPASTEVPRFIAQFLE--------
>tr|A0A0B8WCF8|A0A0B8WCF8_9DELT NAD-dependent deacetylase OS=Bdellovibrio sp. ArHS GN=OM95_09045 PE=3 SV=1
------------------------------------LRLFKNIVILTGAGISAESGIRTFRDQDGLWEEHRIEDVATPEAFARDPQLVQRFYNMRRAQLK
DPQIQPNPAHLALAELERQW--DFLLVTQNVDNLHRRAG-TRLLHMHGRLDQVFCIYCDEHYEWSEDVVLDEACGRKG---GVRPDIVWFGEMPHHMDEI
YAALEKADYFIAIGTSGNVYPAAGFVRLA--WKAKKIEINLKDTEISNAFETHFIGPASSEVPRFIKELLE--------
>tr|W5WZA7|W5WZA7_BDEBC NAD-dependent deacetylase OS=Bdellovibrio bacteriovorus W GN=BDW_10095 PE=3 SV=1
------------------------------------LGSFQRIVILTGAGISAESGIRTFRDQNGLWENHAIEDVASPEGFLRNPALVHRFYNARRAQLK
DPMLKPNTAHLALARLENDFH--FLLVTQNVDNLHKRAG-RNFLQMHGRLDSCFCEICAAQWDWTEDLSTSQRCKSSG---SLRPDIVWFGEMPRSMDEI
LMALHTCDLFISIGTSGHVYPAAGFAQMAQ--RAYKIEVNLSDTEISSAFHERRLGTATEQVPKLVEDILKT-------
>tr|U7G6Q9|U7G6Q9_9GAMM Uncharacterized protein OS=Alcanivorax sp. P2S70 GN=Q670_09205 PE=3 SV=1
--------------------------------------MAENIVILTGAGISAESGIKTFRASDGLWENHRVEDVATPEAFFRNPLMVQQFYNTRREQLL
SATIKPNAAHQALAQLETAW-GQVLLITQNIDNLHERAGSRNLIHMHGELLKGRCQTSGGLLEIDHDLTPAPLCGKPG---CLRPHVVWFGEMPLQMETI
YQALARCDLFISIGTSGNVYPAAGFVEEANRHGAHTIELNLEPSQRLTAFAEHRHGLATDLVPRYVDELLTT-------
>tr|W0Q9A6|W0Q9A6_9PAST Uncharacterized protein OS=Mannheimia varigena USDA-ARS-USMARC-1261 GN=X781_16560 PE=3 SV=1
------------------------------------MEKLPRIVVLTGAGISAESGICTFRAEEGLWENHRVEDVATPEGYKRDRGLVQRFYNERRRKLF
DPEVQPNAAHLALAKLEEKL-ENLLIVTQNVDNLHERAGSKNVIHMHGELLKVRCPNKGTVYEWLGDVEDESCCVQPA---RLRPHIVWFGEIPFQMLEI
DEAIYDCDIFVSIGTSGNVYPAAGFVEKANRWKSHTIELNLEPSKVKTAFKEARYGKATEIVPQFVEEILAS-------
>tr|A0A0B5BT02|A0A0B5BT02_MANHA Uncharacterized protein OS=Mannheimia haemolytica USDA-ARS-USMARC-184 GN=B824_7900 PE=3 SV=1
------------------------------------MKENLKIVVLTGAGISAELGIRTFRAEDGLWENHRVEDVATPEGYKRDPELVQRFYNERRRKLF
DPEVQPNAAHLALAKLEEKL-ENLLIVTQNVDNLHERAGSHNVIHMHGELLKVRCPNKGAVYDWQGDVTDESCCIQPA---RLRPHIVWFGEIPLQMQEI
DEAIYNCDIFVSIGTSGNVYPAAGFVQKANQWKSHTVELNLEPSKVKTAFKETRYGKATEVVPQFAEEILAS-------
>tr|E0F1G6|E0F1G6_ACTPL NAD-dependent deacetylase OS=Actinobacillus pleuropneumoniae serovar 9 str. CVJ13261 GN=appser9_21830 PE=3 SV=1
------------------------------------NKNLPKVVVLTGAGISAESGIETFRASTGLWENHKVDDVATPEGFMRNPELVQRFYNARRARLF
DADVQPNAAHLALAELEEKL-DNFLLVTQNVDNLHERAGSKRIVHMHGELLKVRCVRKGTVYDWQEDITDEQCCQPPQ---KLRPHIVWFGEMPLQMNRI
EDALWECDYFISIGTSGNVYPAAGFVNIADRAGAVTVELNLEPSEKHSSFHSCHQGKATEIVPKCVRELLDK-------
>tr|I3DFB9|I3DFB9_9PAST Transcriptional regulator, Sir2 family OS=Pasteurella bettyae CCUG 2042 GN=HMPREF1052_1475 PE=3 SV=1
------------------------------------MKKDLKIVVLTGAGISAESGIRTFRAEDGLWENHRVEDVATPEGYKRDRELVQRFYNERRRKLF
DPEVQPNAAHLALAELEVKL-ENMLIVTQNVDNLHERAGSKNVIHMHGELLKVRCPNKGSAYEWQGDVTDETCCVQPA---RLRPHIVWFGEMPLEMARI
EKALMDCDIFVSIGTSGNVYPAAGFVQVANNWGAKTVELNLEPSKVKNAFQDAKYGKASEIVPEFVKAVLAQ-------
>tr|A0A0B4XNR7|A0A0B4XNR7_9GAMM NAD-dependent deacetylase OS=Alcanivorax pacificus W11-5 GN=S7S_08520 PE=3 SV=1
------------------------------------SRDALNIVILTGAGISAESGIRTFRGDDGLWENHRLEDVATPEAFLRQPGLVQRFYNERRRQLH
APTLAPNPAHHALARLEQAL-GQVLVVTQNIDNLHERAG-QALIHMHGELLKGRCRLCQAVADVSGDIDGDPACRSTG---CLRPHVVWFGEMPLQMDDI
HEALSRCTLFVSIGTSGNVYPAAGFVDVANDA-AHTLELNLEASRVRTAFREHREGLASVLVPAWVDSLLDG-------
>tr|L0WEB7|L0WEB7_9GAMM NAD-dependent deacetylase OS=Alcanivorax hongdengensis A-11-3 GN=A11A3_04340 PE=3 SV=1
--------------------------------------MAENIVILTGAGISAESGIKTFRAADGLWENHRVEDVATPEAFQRDPVLVQDFYNRRRRQLL
TG-VQPNAAHRALARLEQQYRGEVLLVTQNIDNLHERAG-RNLIHMHGELLKGRCQRSGGLVPVDTDLSVEPLCGASG---CLRPHVVWFGEMPLEMERI
YQTLARCDLFISIGTSGNVYPAAGFVEEANRH-AHTVELNLEPSQRLTSFAEHRHGLASELVPAYVEALIAQ-------
>tr|Q0VQK7|Q0VQK7_ALCBS Transcriptional regulator, Sir2 family OS=Alcanivorax borkumensis (strain ATCC 700651 / DSM 11573 / NCIMB 13689 / SK2) GN=cobB 
--------------------------------------MAENIVILTGAGISAESGIKTFRAADGLWENHRVEDVATPEAFLRNPLLVQNFYNQRRRQLL
TGAIRPNAAHQALATLEKAL-GKVLLVTQNIDNLHERAGSRNLIHMHGELLKGRCQTSGGLVDLDHDLTVAPLCGAKG---CLRPHVVWFGEMPLQMEAI
YRALSQCDRFISIGTSGNVYPAAGFVEEANRHGAHTVELNLEPSQQLTAFAEHRRGLATELVPRYVEELIAG-------
>tr|A0A095SMQ4|A0A095SMQ4_9GAMM NAD-dependent deacetylase OS=Alcanivorax sp. 19-m-6 GN=Y5S_00808 PE=3 SV=1
--------------------------------------MAENIVILTGAGISAESGIKTFRASDGLWENHRVEDVATPEAFFRNPLLVQNFYNQRRDQLQ
TPAIQPNAAHQALAKLEAAYKGNVLVVTQNIDDLHERAG-RQLIHMHGEILKGRCQTSGGLVQIDHDLTPTPLCGKQG---CLRPHVVWFGEMPLQMETI
YRALAHCDRFISIGTSGNVYPAAGFVEEANRH-AHTIELNLEPSQRLTAFAEHRHGLATELVPDYVEELIGL-------
>tr|U7HYQ1|U7HYQ1_9GAMM Uncharacterized protein OS=Alcanivorax sp. PN-3 GN=Q668_09820 PE=3 SV=1
--------------------------------------MQEKIVILTGAGISAESGIRTFRDNGGLWEEHRIEEVATPEAFQRDPVKVHQFYNQRRRQLH
GPAITPNLAHRALARLEAAL-GQVLLVTQNVDNLHERAG-RNLIHMHGELCKARCRTTDALVTVDDELSTGPLCGVPG---CLRPHVVWFGEMPLEMDRI
YAALARCERFISIGTSGNVYPAAGFVAEARAN-AHTVELNLEPSEQLNAFHEHHHGPATQLVPEYVEKLIKA-------
>tr|M2YAK0|M2YAK0_9PROT NAD-dependent deacetylase OS=Magnetospirillum sp. SO-1 GN=H261_10179 PE=3 SV=1
------------------------------------MAGKGSIVILTGAGISKEFGLDTFRDKDGIWSRVRLEDVATPDAFRRDPAKVQAFYNTRRRNLV
EGGIRPNPAHAALARLEREW-GEVLIVTQNIDDLHERAG-ENLIHMHGELLKIRCQKCARPFAWTADVEVGPDCHRLG---TLRPHVVWFGEMPLDMERI
FEALEACALFVSIGTSGHVYPAAGFVQTVRAQRAHTAELNLEPSEGASLFRETRLGPASRLVPAFVEELLSA-------
>tr|A0A0D2WLB5|A0A0D2WLB5_9PROT NAD-dependent deacetylase OS=Skermanella aerolata KACC 11604 GN=N826_03445 PE=3 SV=1
------------------------------------------MVILTGAGISKESGLDTFRCAGGVWERVRLEDVATPEGFDRNPDLVHRFYNDRRSGLL
QADIQPNAAHAALARLERDW-GEVLLVTQNIDDLHERAG-TNLIHMHGELLKARCGVCGEISEIRTDLSVNIACGAVA---EMRPHVVWFGEMPLEMERI
YAALAGCALFVSIGTSGNVYPAAGFVQEARIN-AHTVELNLEPSEGATLFAEKIYGAATAAVPAFVDRILAV-------
>tr|W9H329|W9H329_9PROT NAD-dependent deacetylase OS=Skermanella stibiiresistens SB22 GN=N825_34935 PE=3 SV=1
------------------------------------------MVILTGAGISKESGLDTFRCAGGVWERVRLEDVATPEGFARDPDLVHQFYNDRRTGLL
HANVQPNAAHEALATLEREW-GEVLLVTQNIDDLHERAG-RNLIHMHGELLKARCGACYAVSEIRRDLSVEAGCGAIA---EMRPHVVWFGEMPLEMDRI
YRELAGCALFLSIGTSGNVYPAAGFVQEARVN-AHTVELNLDPSEGATLFDEKIYGPATREVPAFVERLLAL-------
>tr|A0A0C2YPJ4|A0A0C2YPJ4_MAGMG NAD-dependent protein deacetylase of SIR2 family OS=Magnetospirillum magnetotacticum MS-1 GN=CCC_00114 PE=3 SV=1
---------------------------------------MGSIVILTGAGISKESGLDTFRDRDGIWSKVRMEDVATPEGFRRDPARVHAFYNARRRNLA
EGGVTPNAAHAALARLEKDW-GEVLLITQNIDDLHERAG-ENLIHMHGELLKIRCVKCARPFAWTADLGLDPDCYRIG---SLRPHVVWFGEMPLDMERI
MEALMDCALFVSIGTSGHVYPAAGFVQTVRAQRAHTIELNLEPSQGTSLFHETRLGPASQLVPTFVEDLLSR-------
>tr|A0A0N0K764|A0A0N0K764_9PROT NAD-dependent deacetylase OS=alpha proteobacterium AAP38 GN=IP70_21575 PE=3 SV=1
------------------------------------LRPDAGLFILTGAGISRESGLLTFRDGDGLWEKERLEDVATPQAFARDPARVQGFYNARRRAVL
HPDVQPNVAHQALVRLEREW-GPFLLVTQNVDDLHDRAG-ARMLHMHGELLKISCAACDRMAAFSGDLAVDPDCGGRG---TLRPHIVWFGEMPLYMDEI
GQALDEAALFIAIGTSGTVYPAAGFVAATRANGAVTVEVNMEETGG--AFDGGLYGPATQTVPALVNGLLEI-------
>tr|A4TYC8|A4TYC8_9PROT NAD-dependent protein deacetylases, SIR2 family OS=Magnetospirillum gryphiswaldense GN=MGR_1559 PE=3 SV=1
------------------------------------IPATGSIVVLTGAGISKESGLDTFRCEDGIWSKVRLEDVATPEGFQADPDLVHDFYNARRRSLL
DPSLAPDAAHQALAELERRW-GKVLIVTQNIDDLHERAG-RNLIHMHGELLKVRCTHCALPLPWHQDLSVDPDCRRTG---TLRPHVVWFGEIPLQMEQI
MAALMSCDLFVSVGTSGNVYPAAGFVAQVRRLRAHTLELNLDPSEGANLFAESRHGPATRLVPEFIDQLLKD-------
>tr|A0A066RUS1|A0A066RUS1_9GAMM NAD-dependent deacetylase OS=Photobacterium halotolerans GN=EA58_10560 PE=3 SV=1
------------------------------------HFPYRNIVILTGAGISAESGIKTFRDQDGLWENHRIEDVATPEGYQKDPNLVQSFYNQRRKQLE
SGTVKPNAAHYALARLEQAL-GNVTIVTQNIDNLHELAGSQHVIHMHGELLKAQCSQSGQTIDWSGDISLDHCCQIPA---PLRPNVVWFGEMPQGMDKI
YAALTEADLFIAIGTSGSVYPAAGFVHEAAMQGAHTIELNLEPSIIESEFEEKRYGPASQIVPQIVEELLTA-------
>tr|A0A0J8VEU7|A0A0J8VEU7_9GAMM NAD-dependent deacetylase OS=Photobacterium swingsii GN=AB733_08700 PE=3 SV=1
------------------------------------LFPYQNIVVLTGAGISAESGIRTFRDQDGLWENHRIEDVATPEGYLRDPVTVQNFYNLRRQQLE
GGTVEPNAAHLALAELEAKL-GKVTIVTQNIDNLHEAAGSKNIIHMHGELLKAQCSQTGQSIDWTGNITLDHCCQIPA---PMRPNVVWFGEMPIGMGAI
HEAIVEADLFISIGTSGAVYPAAGFVHEAAMHGAHTVELNLEPSDVESEFAEKRYGQASVLVPEFVRELLD--------
>tr|L8J3X5|L8J3X5_9GAMM NAD-dependent protein deacetylase of SIR2 family OS=Photobacterium marinum GN=C942_03586 PE=3 SV=1
------------------------------------LFPYKNIVVLTGAGISAESGISTFRDQDGLWENHRIEDVATPEGYRRNPALVQNFYNQRRQQLE
GGTVDPNAAHLALARLEKEL-GKVTIVTQNIDNLHEKAGSQNVIHMHGELLKAQCSHSGQAVEWSGDISLEHCCQIPA---PLRPNVVWFGEMPIGMDRI
HDALVKADLFVSIGTSGAVYPAAGFVHEAAMHGAHTIELNLEPSEVENEFAEKRYGMASVIVPQFVEEILE--------
>tr|A0A0C5WUK3|A0A0C5WUK3_9GAMM NAD-dependent deacetylase OS=Photobacterium gaetbulicola Gung47 GN=H744_2c2060 PE=3 SV=1
------------------------------------LFPYRNIVVLTGAGISAESGIRTFRDQDGLWENHHIEDVATPEGYYRDPALVQNFYNQRRQQLE
SGAVFPNDAHKALARLEQEL-GKVTIVTQNIDNLHEMAGSKNVIHMHGELLKAQCSETGQTVEWSGDITLDHCCQMPA---PMRPNVVWFGEMPIGMDRI
HEALMEADLFISIGTSGAVYPAAGFVHEAAMHGAHTIELNLEPSEVESEFAEKRYGPASMLVPRFVDEILG--------
>tr|A0A0J1HCU2|A0A0J1HCU2_9GAMM NAD-dependent deacetylase OS=Photobacterium ganghwense GN=ABT57_11725 PE=3 SV=1
------------------------------------KFPYRNIVVLTGAGISAESGIRTFRDQDGLWENHRIEDVATPEGYHRDPGLVQSFYNQRRQQLE
SGTVFPNAAHKALARLEKEL-GKVTVVTQNIDNLHEEAGSKNVIHMHGELLKAQCSRTGQTIEWSGDLSQDHCCQLPS---PLRPNVVWFGEMPIGMDRI
HQALMEADLFISIGTSGAVYPAAGFVHEAALHGAHTVELNLEPSEVESEFTEKRYGPASVIVPEYIHEILEG-------
>tr|Q6LR13|Q6LR13_PHOPR Putative NAD-dependent protein deacetylase OS=Photobacterium profundum GN=VV1691 PE=3 SV=1
------------------------------------LFPYRNIVILTGAGISAESGIRTFRDQDGLWENHHIEDVATPEGYRRDPDLVQNFYNQRRQQLE
SGTVAPNAAHLALSKLEAEL-GTVTIITQNIDNLHEMAGSKNVIHMHGELLKAQCSGTGQSIHWQGDIKLDHCCQIPS---PLRPNVVWFGEMPIGMERI
HDALLTADLFISIGTSGAVYPAAGFVHEAAMHGAHTIELNLEPSEVQSEFAEKRYGPASKVVPEFIDEILSA-------
>tr|A0A0J1H6A2|A0A0J1H6A2_9GAMM NAD-dependent deacetylase OS=Photobacterium aquae GN=ABT56_06930 PE=3 SV=1
------------------------------------QFPYRNIVILTGAGISAESGIRTFRDQDGLWESHRIEDVATPEGYYRDPVLVQNFYNLRRQQLE
SGSVFPNKAHEALALLEQQL-GTVTLVTQNIDNLHEMAGSKNIIHMHGELLKAQCSNTGQTVEWSGDISLDHCCQIPA---PLRPNVVWFGEMPIGMDRI
HQALMEADLFISIGTSGAVYPAAGFVHEAAMHGAHTIELNLEPSEVENEFAEKRYGQASDIVPAYVAELLAI-------
>tr|A0A0F5V8Z4|A0A0F5V8Z4_9GAMM NAD-dependent deacetylase OS=Photobacterium halotolerans GN=KY46_17650 PE=3 SV=1
------------------------------------HFPYRNIVILTGAGISAESGIKTFRDQDGLWENHRIEDVATPEGFKRDPNLVQSFYNQRRQQLE
SGSVQPNAAHYALSRLENEL-GTVTIITQNIDNLHEKAGSHDVIHMHGELLKAQCSQSGQTIEWSGDISLDHCCQIPA---PLRPNVVWFGEMPQSMDKI
YSALVAADLFIAIGTSGSVYPAAGFVHEAAMHGAHTLELNLEPSIVESEFDEKRYGPASQIVPELVEELLTP-------
>tr|E1SMN7|E1SMN7_FERBD Silent information regulator protein Sir2 OS=Ferrimonas balearica (strain DSM 9799 / CCM 4581 / PAT) GN=Fbal_1372 PE=3 SV=1
------------------------------------KRMYQRIVVLTGAGISAESGMKTFRAEDGLWEAHRVEDVATPEGYRRDPDLVNRFYNQRWEQLN
NG-IEPNPAHHALAELEKQL-KGLLVVTQNIDDLHERAG-RRLIHMHGELNKGRCPRSQQVFPLLEPFGNDTCCVPGQ---VLRPHVVWFGEMPLGLDRI
YRALEQCELFISIGTSGTVYPAAGFVEMASHGGADTLEINLEPSEVHSQFSHHQTGRAGELVPKLVEWIKAG-------
>tr|E3BFK9|E3BFK9_9VIBR NAD-dependent deacetylase OS=Vibrio caribbeanicus ATCC BAA-2122 GN=VIBC2010_10372 PE=3 SV=1
------------------------------------NFPYRNIVVLTGAGISAESGIQTFRAEDGLWENHRIEDVATPEGFERDPELVQSFYNQRRLNLQ
LPTIQPNSAHYALAELEKQL-GNVTIITQNIDDLHERAGSQNVIHMHGELLKVRCCESGQTISHTGELKTGHCCQIPT---QLRPHVVWFGEMPLKMDEI
YQRIEQSDLFVSIGTSGVVYPAAGFVHDAKMFGAHTIEINLAPSAVESEFDEKHYGKASEKVPELVKLLLD--------
>tr|U3C849|U3C849_9VIBR NAD-dependent protein deacylase OS=Vibrio azureus NBRC 104587 GN=cobB PE=3 SV=1
------------------------------------NFPYRNIVVLTGAGISAESGIQTFRAQDGLWENHHIEDVATPEGFARDPQMVQRFYDQRRAKLL
EDAIKPNQAHLYLGQLESQL-GKVTIITQNIDNLHERGGSHHIIHMHGELLKARCCESGQVFECNEDLAPEHCCQIPS---PLRPHIVWFGEMPLQMGEI
YGLLEEADLFISIGTSGLVYPAAGFVHDAKMHGAHTIEINLEPSAVESEFEEKRYGKASIEVPKLVKELLGQ-------
>tr|A3K6Z0|A3K6Z0_9RHOB NAD-dependent deacetylase OS=Sagittula stellata E-37 GN=SSE37_13006 PE=3 SV=1
------------------------------------MTRNGKIVILTGAGLSAESGLSTFRDEGGLWSQHRIEDVATPEAFARNPDLVQAFYNARRAQS-
-RAATPNAAHVALARLQRD--GEVVIVTQNVDGLHEKAGA-KVIHLHGALDSALCHLCDHRWTAPETIDSAPACGH-H---SARPDVVWFGEMPYHMEEI
AEHLENADIFASIGTSGQVYPAAGFSQLASDYGAECIELNLEPT--SHVFHQRRIGHATQTILAWVEELIGA-------
>tr|A0A0Q7R262|A0A0Q7R262_9CAUL NAD-dependent deacylase OS=Brevundimonas sp. Root1423 GN=ASD25_13675 PE=4 SV=1
------------------------------------TRNIRNLVILTGAGISAESGVPTFRADDGLWMGHRIEDVATPDAFARDPALVQDFYNRRRRQLS
E--VRPNAAHLALADLAARW-GDILLVTQNVDDLHDRVHAFDLVHMHGELLKVRCTRTGRVCDWPGDLAAHPHHG-EG---RLRPHIVWFGEFPLEMDRI
DGALAACDLFVAIGTSGAVWPAAGFVRQAGFAGAHTVEINLEPTPGSRLFDEGLYGPATETVPAFVEGLLAD-------
>tr|U2ZCR9|U2ZCR9_9CAUL NAD-dependent protein deacetylase of SIR2 family OS=Brevundimonas abyssalis TAR-001 GN=MBEBAB_1520 PE=3 SV=1
-------------------------------------MSKRNLVVLTGAGVSAESGVPTFRAADGLWLGHRVEDVATPEAFARDPALVQDFYNKRRRQLA
T--VHPNAAHRALAALAARW-GGFLLVTQNVDDLHDRAHAFDLIHMHGELRKARCTTSGVVCDCPDDLETDPHHP-AG---RLRPHIVWFGEIPLEMDRI
EQALSRCDLFLSIGTSGAVWPAAGFVQAARMAGARTVEINLEPTAGRRLFDEASTARRP--------------------
>tr|A0A0N0K7G6|A0A0N0K7G6_9CAUL NAD-dependent deacetylase OS=Brevundimonas sp. AAP58 GN=IP78_02335 PE=3 SV=1
-------------------------------------MAHGNIVILTGAGISAESGVPTFRSDDGLWLGHRVEDVATPEAFASDPTKVQAFYNQRRRQM-
-AEVQPNAAHRAIADFAAR--GRLTLVTQNVDDLHDRAQAFELIHMHGELLKAQCTATGRVLDWTDDLDAYPFSPD-G---WLRPHIVWFGEFPLHMDRI
EGALSRCDLFVSIGTSGEVYPAAGFVRRARMAGARTVEINLEPSQGAALFDQCIHGPATEIVPVFLDTL----------
>tr|A0A0Q7SPZ8|A0A0Q7SPZ8_9CAUL NAD-dependent deacylase OS=Brevundimonas sp. Root1423 GN=ASD25_06765 PE=4 SV=1
-------------------------------------MRHRNLVILTGAGISAESGVPTFRADDGLWLGHRIEDVATPGAFARDPSLVQDFYNRRRRQLA
E--VRPNAAHHALADLAARW-GDFLLVTQNVDDLHDRAHAFELIHMHGELLKAHCTRTGRVCDWPDDLEPQPHHP-LG---LLRPHIVWFGEMPFMLERI
DAAIAACDLFISIGTSGAVYPAAGFVQQARFAGARTVEINLEPTPGSRLFDQGVYGPATQMVPAFVNNLLAG-------
>tr|A0A0Q7EDL9|A0A0Q7EDL9_9CAUL NAD-dependent deacylase OS=Brevundimonas sp. Root1279 GN=ASC65_08405 PE=4 SV=1
-------------------------------------MTYNSLVILTGAGISAESGVPTFRADDGLWMGHRIEDVATPEAYARDPALVQDFYNKRRRQLG
E--VQPNAAHRALAELAARW-GDFLLVTQNVDDLHDRAHAFSLIHMHGELLKARCTASGRVCDWVEDLDVRPF-HPDG---WLRPHIVWFGEMPLAMHVI
DAALERCDLFVSIGTSGAVYPAAGLVQQARRAGARTVEINLEPSQGARQFDEGLYGPATERVPEFVERLLQR-------
>tr|A6FIB3|A6FIB3_9GAMM NAD-dependent deacetylase OS=Moritella sp. PE36 GN=PE36_11337 PE=3 SV=1
------------------------------------FDTYNNIVILTGSGISAESGIETFRASDGLWAKHHIDDIATLEGYRRDPELVYSFYNQRFNQLS
LPSIQPNDAHVALAELQKNYS-NVTIVTQNIDNLHERGG-NDIIHMHGELVKARCEKTQKLFPYKQL-NKSPCCKEQG---NLRPHVVWFNEMPLFMNDI
YKSLSKADLFIAIGTSGSVYPAADFVNEANKVCAHTIEINLDATHISDNFREHRVGKATDEVRELVEELMAR-------
>tr|A0A090K8Q1|A0A090K8Q1_9GAMM NAD-dependent deacetylase OS=Moritella viscosa GN=npdA PE=3 SV=1
------------------------------------FDNYNDIVILTGSGISAESGIETFRASDGLWAKHHIDDIATLDGYRRDPELVYSFYNQRFNQLS
LPSVQPNDAHIALAELQNNYS-NVSIITQNIDNLHERGG-KNVIHMHGELVKARCEKTHKLFPYKQL-NKTPCCKEPG---NLRPHIVWFNEMPLFMNDI
YKSLSTADLFIAIGTSGSVYPAADFVNEAHKVRAHTIEINLDSTHISDNFQEHRIGNATDEVRELVDELMAR-------
>tr|A0A0R2X345|A0A0R2X345_9GAMM NAD-dependent deacetylase OS=OM182 bacterium BACL3 MAG-120924-bin41 GN=ABS30_00975 PE=4 SV=1
------------------------------------SSGLRSVVVLTGAGISAESGIQTFRASDGLWEEHRIEDVASPEGFARNPALVYDFYNQRRRQVQ
AAAITPNAAHTALARFEHDA--EFLLVTQNVDNLHERAG-QALSHMHGELLKSRCVNSGLVFDWRQDLGFDRCCQQRG---NLRPHIVWFGEMPLGMSQI
EAALARCDLFVSIGTSGNVYPAAGFGQLAQQAGATTVELNLDRT--GSVFDEHHYGPATKSVPAFFSNLA---------
>tr|A5PCR8|A5PCR8_9SPHN NAD-dependent deacetylase OS=Erythrobacter sp. SD-21 GN=ED21_22818 PE=3 SV=1
------------------------------------MSDIRNIVVLTGAGISAESGIDTFRD-GGLWEQHRVEDVATPEGFSRDPDLVHRFYDARREAVQ
Q--VEPNPAHEALALLDKRW-GNLLIVTQNVDDLHERAGASRVLHMHGELLSALCARCDARHRWSEPLF-RPGCGEA----ALRPDVVWFGEMPYEMERI
YDALRRADMFVSIGTSGAVYPAAGFVRDAREFGARTLELNLERGEGSYWFHESRQGRASKLVPEWVGEVLAS-------
>tr|A0A0M4MTQ1|A0A0M4MTQ1_9SPHN NAD-dependent protein deacetylase of SIR2 family OS=Altererythrobacter epoxidivorans GN=AMC99_00234 PE=3 SV=1
------------------------------------MEKPRSIVILTGAGISAESGIDTFRD-GGLWEQHRVEDVATPEGFARDPELVLGFYDMRRAALA
N--VRPNAAHEALARLDAEFG-ELLIVTQNVDDLHERAGARRVLHMHGELKSALCSSCEMRSPWDAPMSARPVCQAP----SLRPDVVWFGEMPYQMERI
YRAIRKADLFVSIGTSGAVYPAAGFVRDARDLGARALELNLERSEGSHWFHESRQGRAGELVPEWVEEILG--------
>tr|V5HJY2|V5HJY2_9VIBR NAD-dependent protein deacylase OS=Vibrio halioticoli NBRC 102217 GN=cobB PE=3 SV=1
------------------------------------VFPYKNIVILTGAGISAESGIETFRAQDGLWENHRIEDVATPEGFDRDPILVHSFYNMRRQKLL
SAAIKPNAAHIALGHLEQTI-GTVTVVTQNIDNLHERGGSNNIIHMHGELLKVRCSGSGQVIEQGSDLNDGHCCQIPQ---QMRPHIVWFGEMPLQMDKI
YSAIEEADLFISIGTSGVVYPAAGFVHDAKLHGAHTIEINLEPSAVQSEFDEKRYGRASVEVPRLVGELLGQ-------
>tr|A7N0S2|A7N0S2_VIBCB Uncharacterized protein OS=Vibrio campbellii (strain ATCC BAA-1116 / BB120) GN=VIBHAR_02284 PE=3 SV=1
------------------------------------NFLYRNIVVLTGAGISAESGIQTFRAQDGLWENHRIEDVATPEGFLRDPDLVQSFYNQRRKKLQ
GEDIKPNAAHIALGRLEEQL-GKVTIITQNIDNLHERGGSANIIHMHGELLKARCSESNQVIEHSEDIETGHCCQIPS---QMRPHIVWFGEMPLRMGEI
YAALEEADLFISIGTSGVVYPAAGFVHDAKMHGAHTIEINLEPSAVESEFEEKRHGKASIEVPKLVDEILAL-------
>tr|A0A084CNG2|A0A084CNG2_9GAMM NAD-dependent deacetylase OS=Candidatus Photodesmus blepharus GN=cobB PE=3 SV=1
-------------------------------------MQYNNVVILTGAGISAESGIRTFRSKDGLWENHRIEDIATKEGFIRNPYLVQEFYNQRRRMLQ
FDNIQPNLAHKALGRLEREL-GKVTIITQNIDNLHERGGSKNVIHMHGELLKASCITSGQVIEHKSDILVDRCCRIPS---PIRPHIVWFGETPLRMADI
YSALNEVDLFVSIGTSGIVYPAASFVYDAKICGAHTIEINLEKTPIENVFQEKRYGNASTEVDKLVSELLCL-------
>tr|B6ELV2|B6ELV2_ALISL NAD-dependent deacetylase OS=Aliivibrio salmonicida (strain LFI1238) GN=npdA PE=3 SV=1
------------------------------------LFPYKNIVILTGAGISAESGIQTFRASDGLWENHRIEDVATPEGFFKDPDLVQDFYNKRRALLK
SDAIQPNAAHKALARLEKEL-GTVTIVTQNIDDLHERGGSKNVIHMHGELNKIRCEESNQVIACTDDIQTGHCCQIPA---QLRPHVVWFGEMPLEMGRI
HDLLSQADLFISIGTSGSVYPAAGFVHEATLHGAHTIEINLEASAVEDEFEEKRYGKAGVLVPELVSELLEV-------
>tr|A0A0C2NII7|A0A0C2NII7_9VIBR NAD-dependent deacetylase OS=Vibrio sp. DCR 1-4-12 GN=PL18_06630 PE=3 SV=1
------------------------------------DFPYRNIVILTGAGISAESGIQTFRAQDGLWENHRIEDVATPEGFERDPDLVQDFYNQRRNKLQ
DEAIKPNAAHNALGRLEQSL-GHVTIITQNIDNLHERGGSQNIIHMHGELLKARCSESNQVVEHDHNIETGHCCQIPS---QMRPHIVWFGEMPLRMGDI
YAAIEKADLFISIGTSGVVYPAAGFVHDARMHGAHTIEINLEPSAVESEFEEKRYGKASVEVPRLVDEILAM-------
>tr|A0A090P1Q0|A0A090P1Q0_9VIBR NAD-dependent protein deacetylase OS=Vibrio ponticus GN=JCM19238_823 PE=3 SV=1
------------------------------------EFPYRNIVVLTGAGISAESGIQTFRTQDGLWENHRIEDVATPEGFARDPDLVQDFYNQRRRKLQ
GDSIQPNAAHNALGRLEQEL-GTVTIITQNIDNLHERGGSENVIHMHGELLKARCSESNQVIDHNEDIQTGHCCQMPA---QMRPHIVWFGEMPLRMGDI
YSAIEKADLFVSIGTSGVVYPAAGFVHDARMHGAHTIEINLEPSAVESEFKEKRYGKASVEVPKLVDEILAV-------
>tr|M5RE45|M5RE45_9PLAN Silent information regulator protein Sir2 OS=Rhodopirellula maiorica SM1 GN=RMSM_05745 PE=3 SV=1
----------------------------------------MKILILTGAGISAESGVPTFRDANGLWEGHRFEDVATPQAFQRNPELVQDFYNQRRRSLL
DAKIQPNAAHRALADFEATH-DDFLLVTQNIDDLHVRAGSKKVLPMHGELLKARCTHTGEVFPWREDLDETT--EIRG---TLRPHVVWFGEMPLGLEQI
EVAARQADLFIAIGTSAVVYPAAGIVRQTKP-SCRKIEINLDATPNSGQFDESIRGKASVEVPAFLSSLSVS-------
>tr|W6KEK7|W6KEK7_9TRYP Uncharacterized protein OS=Phytomonas sp. isolate EM1 GN=GSEM1_T00003141001 PE=3 SV=1
------------------------------------MQKLRNILILTGAGISVESGLSTFRDSNGLWCNHRIEDVATLEAFALQPEVVQRFYNERRRKLQ
EACVKPNAAHYALARLQREMK--VHIVTQNVDNLHERAG-TDVVHMHGELLKARCRFTDEVFDIVGDIPAKTCCNELG---TLRPHIVWFGEMPLFMEKI
EELLSKTELFVCIGSSGQVYPAAGFVTRARFAGAKTLEINIEKTGDYNDFSKTLIGKASEVVPKWVDSMLDG-------
>tr|W6KWK5|W6KWK5_9TRYP Uncharacterized protein OS=Phytomonas sp. isolate Hart1 GN=GSHART1_T00000841001 PE=3 SV=1
------------------------------------MSKFRNIVILTGAGISSESGLATFRKQDGLWCNHRIEEVATMAAFLANPELVHRFYNERRRRLQ
AAEVKPNAAHDALARLQRAMP--VHLITQNVDNLHERAG-TQVLHMHGELLKARCRLTDTMYDISGDIPASGCCQELG---TLRPHIVWFGEMPLCMDQI
EACLAKTELFVSIGTSGQVYPAAGFVTRARLRGAQTLEINLEKTNDYNEFEQTLIGKASEVVPKWVETMLDG-------
>tr|S9U4Z5|S9U4Z5_9TRYP NAD dependent deacetylase OS=Angomonas deanei GN=AGDE_11650 PE=3 SV=1
------------------------------------GRAMRHITILTGAGISAESGVPTFRDANGLWHNHKIEDVASYDGYVRNPSLVQSFYNARRRALL
DPAVQPNAAHFSLAKLQREF--KVCLVTQNVDNLHERAGSANVLHMHGELFKVHCKNTQQVYKWEGDIDIKACCDEVG---TLRPHIVWFGEMPLHMDDI
AAEMVETDLFVSIGTSGVVYPAAGFVREARQYGALTLELNLECS-DATAFNTSLQGKETELVPKWVDSVLDG-------
>tr|A0A0N1L1V7|A0A0N1L1V7_9SPHN NAD-dependent deacetylase OS=Novosphingobium sp. AAP1 GN=IP65_17535 PE=3 SV=1
------------------------------------MSLPKHIVILTGAGVSAESGIDTFRSGPSLWEQHRVEDVATPEAFVRDPDLVLRFYDMRRAAI-
-QEKLPNAAHRALARLEHAWAGSVTLVTQNVDDLHRRAGSDNLIPMHGQHLSAWCTACDSRHAWTGPLIDRPSCGT-A---ALRPDIVWFGEVPYRMDDI
HDAMARADLFVSIGTSGAVYPAAGFVRLAREIGAETLELNLDRSQGSAWFHDTRLGPATQIVPDWVDELLKT-------
>tr|C9P4R7|C9P4R7_VIBME NAD-dependent protein deacetylase of SIR2 family OS=Vibrio metschnikovii CIP 69.14 GN=VIB_001285 PE=3 SV=1
------------------------------------NFPYRNIVVLTGAGISAESGIQTFRAQDGLWENHRIEDVATPEGFARDPDLVQDFYNQRRRKLG
SPEIQPNAAHLALGELERRL-GSVTIITQNIDDLHERGGSQNVIHMHGELFKARRSMSNQVVEQKGDLLTGHCCQIPQ---QMRPHIVWFGEMPLRMGDI
YSALEKADLFVSIGTSGVVYPAAGFVHDARMHGAHTIEINLEPSAIESEFAEKRYGKATLEVPRLVKELLML-------
>tr|A3ULU1|A3ULU1_VIBSP NAD-dependent deacetylase OS=Vibrio splendidus 12B01 GN=V12B01_25134 PE=3 SV=1
------------------------------------HFPYRNIVILTGAGISAESGIQTFRAQDGLWENHKIEDVATPEGFAKDPDLVQEFYNKRRHGLQ
NESILPNTAHKALGELEEKL-GKVTIITQNIDNLHERGGSNNIIHMHGELLKARCSESNQVLEHKDDIHTGHCCQIPA---QMRPHIVWFGEMPLRMGDI
YSALEEADLFISIGTSGVVYPAAGFVHDARMHGAHTIEINLEPSAVESEFEEKRYGKASIEVPKLVGELLCS-------
>tr|R5EHV2|R5EHV2_9GAMM Transcriptional regulator Sir2 family OS=Succinatimonas sp. CAG:777 GN=BN779_00709 PE=3 SV=1
--------------------------------------MYQNIVILTGAGISAESGIPVFRSETGLWEQERVEDVATYDGFLRDKTKVHEFYNKMRRSL-
-LDKKPNPAHLALARLEKEYKANVNLVTQNIDDLHEKAGSEKIIHMHGRLKSILCEHCNKRYPFNDDSSIEKFCHH-K---SLRPDIVWFGEMPYQMDEI
ETLLSKCDLFLSIGTSGVVYPAAGFCQVARASGAACIEFNLSQSAVGSQFNCGIYGKASKTLPEFVSALIDT-------
>tr|G6F1L4|G6F1L4_9PROT Silent information regulator protein Sir2 OS=Commensalibacter intestini A911 GN=CIN_15100 PE=3 SV=1
---------------------------------------MKKIVILTGAGVSKESGLDTFRDANGIWAKYSMEEVCTPEGFKKNPEKLQEFYNKLRKDL-
-PKVQPNAAHIALAALEKSIQAELLIVTQNIDDLHERAGSQNLYHMHGELYKLWCTACDAKIEWHQDCTIHSHCGQ-H---KLRPDIVWFGEMPYYMDEI
QEALLSCDLFVSIGTSGVVYPAAGFVQLASSAKAKTIELNLEPSAGTSRFNESRLGPATQLVPEFVQQVLKG-------
>tr|W7DUT4|W7DUT4_9PROT NAD-dependent deacetylase OS=Commensalibacter sp. MX01 GN=COMX_08470 PE=3 SV=1
---------------------------------------MKKIVILTGAGVSKESGLDTFRDANGIWAKYSMEEVCTPEGFKRNPQKLHEFYNKLRNDL-
-PNVQPNAAHIALAELEKAIQAELIIITQNIDDLHERAGSKKLYHMHGELYKLWCRGCDAKIKWQHDCFIDPHCGQ-Q---KLRPDIVWFGEMPYDMDKI
QSALLSCDLFVSIGTSGVVYPAAGFVQMASSGHAKTVELNLEPSAGTTCFNESKLGPATQLVPQFVEQVLKD-------
>tr|E8LK44|E8LK44_9GAMM Transcriptional regulator, Sir2 family OS=Succinatimonas hippei YIT 12066 GN=HMPREF9444_01081 PE=3 SV=1
-------------------------------------MRYQNIVILTGAGVSAESGIPVFRSEDGLWEHHNVEDVATYEGFLRNKTLVHEFYNKMRLSL-
-PTKKPNAAHKAIAHLQTEWKGEVFLVTQNIDDLHERAGSKQVCHMHGELLKMLCENCHSSFPFSGASSVKPYCKH-Q---SLRPDIVWFGEMPYDMDEI
YAKLVKCELFLAVGTSGVVYPAAGFCQIAAGAGAVCVEFNLEKSLTASNFTYGIYGKAGETVSKFTEYLLGT-------
>tr|T0DIR7|T0DIR7_9DELT Transcriptional regulator, Sir2 family OS=Bacteriovorax sp. BAL6_X GN=M902_2573 PE=3 SV=1
------------------------------------LAGIKNICLLTGAGISKESGLKTFRDQNGLWENHDIYEVASPLAFNNNPNLVHEFYNQRRRQLL
SSEVHPNDAHLALAELEKSG-FETTIITQNVDNLHERSGSKSIFHMHGQLLKIRCKNTKKIYECNDDLTVEQCCHTKG---NLRPHIVWFGEVPLYLDEI
QETLQKCDLFISIGTSGLVYPAANFVAIAKSAGAHCIEINPHPTNNAELFDETITEVATQGVRHFVESMLQT-------
>tr|T0RBW1|T0RBW1_9DELT Transcriptional regulator, Sir2 family OS=Bacteriovorax sp. Seq25_V GN=M900_1284 PE=3 SV=1
------------------------------------NKKPKHIVILTGAGISAESGIMTFRDSNGLWENHSVYEVASPDGFQRDPELVHRFYNLRRQQLL
SGEVHPNPAHLALSKLQEKFN-IVTIITQNVDDLHERSG-RNVIHMHGELLKMRCIETGRSLTIKKDIHATPCCLKEG---NLRPHIVWFGERPMHMDKI
DTELHSCDLFVAIGTSGHVYPAAMFVDTARERGVQTIEINLESTQISDSFDFHLVGNASVETEKFVEELLT--------
>tr|E1WZQ2|E1WZQ2_HALMS NAD-dependent deacetylase (Regulatory protein SIR2 homolog) OS=Halobacteriovorax marinus (strain ATCC BAA-682 / DSM 15412 / SJ)
------------------------------------PNNFKNIVILTGAGISAESGIKTFRDCNGLWENHDIMEVASIQGFRNNPKLVYDFYNARKAQLQ
SSEVSPNAAHHALAQLESKFK-NVTIITQNVDDLHERSG-HNIIHMHGELLKARCQKSQKVFTIKTNINESSCCREAG---NLRPHIVWFGETPLMLDEI
ELELSKCDLFLSIGTSGEVYPAASFINYVKELGAMTIEQNLQPTKQARLFDIQITGEATKEVPRLVERLLS--------
>tr|T0SJL1|T0SJL1_9DELT Transcriptional regulator, Sir2 family OS=Bacteriovorax sp. BSW11_IV GN=M899_0404 PE=3 SV=1
------------------------------------DNKNKKIVILTGAGISAESGIKTFRDQNGLWEDHNILEVASPQGFERDPELVHRFYNMRRKQLL
SSEVAPNEAHLAVARLQRELP-EIFLITQNVDNLHERAG-PQVLHMHGELTKMRCIESKKVFEIKENISAHPCCLKEG---NLRPHIVWFGETPFSMDEI
YHHTAQCDLFIAIGTSGVVYPAAMLVDLARENGAHTLEFNLNDTQVSDSFHQHIVGPASQTVPKYVEELLNS-------
>tr|U2ZC63|U2ZC63_VIBPR NAD-dependent protein deacylase OS=Vibrio proteolyticus NBRC 13287 GN=cobB PE=3 SV=1
------------------------------------KFPYRNIVVLTGAGISAESGIQTFRAQDGLWENHRIEDVATPEGFERNPDLVQDFYNQRRRNLQ
SDTIHPNAAHIALGKLEKEL-GKVTVITQNIDNLHERGGSTHVIHMHGELLKARCSESNQVVEHNDDIHTGHCCQMPA---QMRPHVVWFGEMPLRMGEI
YSSLEEADLFISIGTSGVVYPAAGFVHDARMHGAHTIEINLEPSAVESEFEEKRYGKASIEVPKLVEEILSL-------
>tr|F0LTV9|F0LTV9_VIBFN NAD-dependent deacetylase OS=Vibrio furnissii (strain DSM 14383 / NCTC 11218) GN=vfu_A01889 PE=3 SV=1
------------------------------------NFPYRNVVVLTGAGISAESGIQTFRAQDGLWENHRIEDVATPEGFERDPNLVQDFYNQRRRKLQ
SESIQPNAAHIALGKLEKAL-GSVTIITQNIDNLHERGGSQNIIHMHGELLKARCSVSNQVVEHKDDILTGHCCQMPS---QMRPHIVWFGEMPLRMGDI
YAALEQADLFISIGTSGVVYPAAGFVHDAKMHGAHTIEINLEPSAVESEFAEKRYGKASVEVPRLVEEILAL-------
>tr|A0A090R456|A0A090R456_9VIBR NAD-dependent protein deacetylase of SIR2 family OS=Vibrio sp. C7 GN=JCM19233_913 PE=3 SV=1
------------------------------------SKSIHNIVILTGAGISAESGIQTFRAQDGLWENHRIEEVATPEGYERNPELVQEFYNKRRAGLK
RPSIKPNAAHTALGELAKHF-GKVTVVTQNIDNLHERGGSQGVIHMHGELLKARCPVSNQVIDMQDDIKAGHCCQLPS---QLRPHVVWFGEMPLQMGEI
YSLLQEADLFISIGTSGVVYPAAGFVHDAKMHGAHTVEINLEPSAVESEFAEKRYGLASVEVPKIVAELLRG-------
>tr|A0A090SG91|A0A090SG91_9VIBR NAD-dependent protein deacetylase of SIR2 family OS=Vibrio variabilis GN=JCM19239_3793 PE=3 SV=1
------------------------------------KFPYKNVVVLTGAGISAESGIQTFRAQDGLWENHRIEDVATPEGFVRDPDLVQHFYNQRRRKLQ
HENILPNAAHIALGQLENEL-GSVTVITQNIDNLHERGGSENIIHMHGELLKARCEESGQVVEMKDDIMTGHCCQIPS---QMRPHIVWFGEMPLRMGDI
YAAIEQADLFISIGTSGVVYPAAGFVHDAKMHGAHTIEINLEPSAVESEFEEKRYGKASLEVPKLVKEILAL-------
>tr|A0A0L7YSK6|A0A0L7YSK6_VIBAL NAD-dependent deacetylase OS=Vibrio alginolyticus GN=ACS86_15420 PE=3 SV=1
------------------------------------NFPYKNIVILTGAGISAESGIKTFRAQDGLWENHRIEDVATPEGFARNPDLVQDFYNQRRRKLQ
SDAIQPNAAHIALGKLEQES-GKVTIITQNIDNLHERGGSTNVIHMHGELLKARCSASNQVIEHKDDILTGHCCQFPA---QMRPHIVWFGEMPLRMGDI
YSALEEADLFISIGTSGVVFPAAGFVHDARMHGAHTIEINLEPSAVESEFEEKRYGKASIEVPQLVEELLAL-------
>tr|A0A084T4Q9|A0A084T4Q9_9VIBR NAD-dependent deacetylase OS=Vibrio sp. ER1A GN=HW45_25395 PE=3 SV=1
------------------------------------KFPYKNVVVLTGAGISAESGIQTFRAQDGLWENHRIEDVATPEGFARNPELVQSFYNQRRQKLQ
QTDIRPNAAHIALGELERQL-GTVTVITQNIDNLHERGGSENIIHMHGELLRARCSESGQVVEMVNDIETGHCCQIPS---QMRPHIVWFGEMPLKMGDI
YAALEKADLFISIGTSGVVYPAAGFVHDAKMHGAHTIEINLEPSAVQSEFEEKRYGKASIEVPKLVREILAL-------
>tr|A0A0M0HNN5|A0A0M0HNN5_VIBNE NAD-dependent deacetylase OS=Vibrio nereis GN=AKJ17_08765 PE=3 SV=1
------------------------------------KFPYRNVVVLTGAGISAESGIQTFRAQDGLWENHRIEDVATPEGFDRDPDLVQDFYNQRRLKLQ
DPQIEPNPAHLALGKLEQEL-GSVTIITQNIDNLHERGGSHNVIHMHGELLKARCSESNQVVEEKGEIKTGHCCQMPS---QLRPHVVWFGEMPLRMGDI
YEALEKADLFVSIGTSGVVYPAAGFVHDARAHGAHTIEINLEPSAIESEFEEKRYGRASEQVPKLVEEILAL-------
>tr|A0A086WR65|A0A086WR65_9VIBR NAD-dependent deacetylase OS=Vibrio sp. B183 GN=IX95_10010 PE=3 SV=1
------------------------------------KFPYNNIVVLTGAGISAESGIQTFRAQDGLWEDHRIEDVATPEGFERNPDLVQDFYNQRRLKLQ
EEGIEPNAAHLALGRLEKEL-GTVTIITQNIDNLHERGGSVNVIHMHGELLKARCSESNQVVEEKGEVKTGHCCQIPS---QMRPHVVWFGEMPLRMGDI
YESLEKADLFISIGTSGVVYPAAGFVHDAKMHGAHTLEINLEPSAVESEFEEKRYGKASIEVPKLVEEILAL-------
>tr|A0A0C1S4K6|A0A0C1S4K6_9VIBR NAD-dependent deacetylase OS=Vibrio ichthyoenteri GN=SE23_20350 PE=3 SV=1
------------------------------------KFPYRNVVILTGAGISVESGIQTFRAQDGLWEDHRIEDVATPEGFARDPDLVQDFYNKRRIMLQ
EPHIEPNAAHIALGQLEAEL-GTVTVITQNIDNLHERGGSSNVIHMHGELLKARCSVSNQVVEELGEIKTGHCCQMPS---QMRPHVVWFGEMPLRMGEI
YQSLEDADLFISIGTSGVVFPAAGFVHDAKMHGAHTIEINLEPSAVESEFEEKRYGKASVEVPKLVEEILAL-------
>tr|A0A0A5I653|A0A0A5I653_9VIBR NAD-dependent deacetylase OS=Vibrio tubiashii GN=NM22_16705 PE=3 SV=1
------------------------------------NFPYRNVVILTGAGISAESGIQTFRAQDGLWENHIIEDVATPEGFERNPDLVQDFYNKRRLGLQ
NPAIKPNAAHNALGKLEAEL-GTVTIITQNIDNLHERGGNSDVIHMHGELLKARCSESNQVIEEKGEIHTGHCCQIPS---QMRPHVVWFGEMPLRMGDI
YAALESADLFISIGTSGVVYPAAGFVHDAKMHGAHTIEINLEPSAVESEFEEKRYGKASVEVPKLVEEILAL-------
>tr|A0A0F2HZF0|A0A0F2HZF0_9VIBR NAD-dependent deacetylase OS=Vibrio sp. S234-5 GN=UF06_10000 PE=3 SV=1
------------------------------------NFPYQNIVVLTGAGISAESGIQTFRAQDGLWENHRIEDVATPEGFAKNPDLVQEFYNQRRRKLQ
GENIEPNAAHNALGRLEQEL-GKVTIITQNIDNLHERGGSKNIIHMHGELLKSRCSVSNQVIEQSGDILTGHCCQMPA---QMRPHIVWFGEMPLRMGDI
YAALEEADLFVSIGTSGVVYPAAGFVHDAKMHGAHTIEINLEPSALESEFAEKRYGKASVEVPRLVEELLAH-------
>tr|A0A0H0XU15|A0A0H0XU15_VIBVL NAD-dependent deacetylase OS=Vibrio vulnificus CladeA-yb158 GN=VVYB158_20715 PE=3 SV=1
------------------------------------NFPYRNIVVLTGAGISAESGIQTFRAQDGLWENHRIEDVATPEGFARDPDLVQDFYNQRRKKLQ
DPNIEPNAAHLALGRLEAEL-GQVTIVTQNIDNLHERGGNKNIIHMHGELLKSRCSVSNQVIEETGNILTGHCCQMPS---QMRPHVVWFGEMPLRMGEI
YSALETADLFISIGTSGVVYPAAGFVHDAKMHGAHTIEINLEPSAIESEFVEKRYGKASVEVPKLVEELLAH-------
>tr|U4E5I3|U4E5I3_9VIBR NAD-dependent deacetylase OS=Vibrio nigripulchritudo FTn2 GN=npdA PE=3 SV=1
------------------------------------NFPYRNIVILTGAGISAESGIQTFRAQDGLWENHRIEDVATPEGFQRNPELVQEFYNQRRRKLQ
DPAIKPNTAHEALGKLEAQL-GKVTVITQNIDNLHERGGTKNIIHMHGELLKARCSESNQVVDCSEDILSGHCCQMPT---QMRPHIVWFGEMPLRMGEI
YLALEEADLFISIGTSGVVYPAAGFVHDARMHGAHTIEINLEPSAVESEFEEKRYGKASIEVPKLVEELLSE-------
>tr|A0A0D6NFY2|A0A0D6NFY2_9PROT NAD dependent deacetylase OS=Acetobacter indonesiensis 5H-1 GN=Abin_062_020 PE=3 SV=1
------------------------------------AFFAERIVILTGAGISQESGLATFRDEGGLWAAHAIEDVCTPEGFLRNPALVDDFYNQRRREV-
-QSAQPNAAHNALADLEAAFTDHFLLITQNIDPLHERAGSRSLVHMHGELERVLCKTCQKTFAWVDDCLPDPHCQH-N---TLRPDVVWFGEMPYHMTRI
EKALAECTLFVAIGTSATVWPAAGFVQTA-SHHAHTVELNLAPSGASGLFDEVLYGPATKIVPRYVKGLAQA-------
>tr|F7VGU2|F7VGU2_9PROT Silent information regulator protein Sir2 OS=Acetobacter tropicalis NBRC 101654 GN=ATPR_2591 PE=3 SV=1
------------------------------------SLLSERIVILTGAGISQESGLATFRDEGGLWASHSIEDVCTPEGFSRNPALVDDFYNHRRKEA-
-QTVEPNVAHKALAMLEAALNDRFLLITQNIDPLHERAGSRSLVHMHGELERVRCTACHQSFQWITDCFPTPHCGA-A---ALRPDVVWFGEMPYHMERI
EKALARCTLFIAIGTSATVWPAAGFVQAA-GAHAHTVELNLAPSAASGQFDEVLYGPATKVVPRYVSGLLTP-------
>tr|A0A0Q5PI64|A0A0Q5PI64_9SPHN NAD-dependent deacylase OS=Sphingomonas sp. Leaf343 GN=ASG07_14415 PE=4 SV=1
------------------------------------MTATPAIVVLTGAGISAESGLATFRG-GGLWEGHRVEDVCTPQALARDPELVHRFYDARRAALA
T--VEPNAAHLALARLDAAW-GDLLIVTQNVDDLHERAGARRLLHIHGELRSALCARCEARSEHDGDLPP-VACGA-P---ALRPDIVFFGEMPYHMEAI
EAALAACDLFVSIGTSGAVYPAAGFVQLADHYGADTLELNLEPSAGSASFAQSRHGPASLLVPAWIDSLLN--------
>tr|A0A097EGZ0|A0A097EGZ0_9SPHN NAD-dependent deacetylase OS=Sphingomonas taxi GN=MC45_11165 PE=3 SV=1
------------------------------------MTDIRNIVVLTGAGVSAESGIATFRG-GGLWEGHRVEDVCTPEALAADPVLVHRFYDLRRAALA
G--VGPNAAHRALAELDAAW-GDLLIVTQNVDDLHERAGARRLLHMHGELTSALCARCGVRRGWHDALPP-DACGA-A---ALRPDIVFFGEMPYQMERI
EAALARADLFVSIGTSGAVYPAAGFVQLADAYGAETLELNLERSAGSGFFAETRLGPAGVLVPDWVREVLGQ-------
>tr|G2IM99|G2IM99_9SPHN NAD-dependent deacetylase OS=Sphingobium sp. SYK-6 GN=npdA PE=3 SV=1
------------------------------------MSEVHNIVILTGAGISAESGLATFRG-GGLWEGHRVEDVCTPGALARDPALVHRFYDLRRAALA
G--VAPNDAHAALARLERAW-GDFLIVTQNVDDLHERAGSRRVLHMHGELLSALCAACGHRLAWQGSLAP-LSCRA-P---RLRPDIVFFGEMPYAMERI
EAALSRADLFVSIGTSGAVYPAAGFVRMAGAFGAATLELNLEPSAGSDWFDACRHGPASVVVPAWVDEMLAP-------
>tr|A0A0A1W4E1|A0A0A1W4E1_9SPHN NAD-dependent protein deacylase OS=Sphingomonas parapaucimobilis NBRC 15100 GN=cobB PE=3 SV=1
------------------------------------MHPIRNIVILTGAGVSAESGIATFRG-GRLWEGHRVEDVCTPEALAADPDLVHRFYDLRRAALA
G--VAPNAAHEALARLDREW-GALLIVTQNVDDLHERAGAERMLHMHGALKQALCAACGERFDWPGDLPH-PACAA-P---RLRPDIVFFGEIPYHMERI
EAALAKADLFVSIGTSGAVYPAAGFVRMASAYGAATLELNLDRSEGSGWFDESRLGPAGQLVPEWVEQMLSR-------
>tr|A0A0Q4UQH3|A0A0Q4UQH3_9SPHN NAD-dependent deacylase OS=Sphingomonas sp. Leaf257 GN=ASF14_14795 PE=4 SV=1
------------------------------------MTDLQNIVILTGAGISAESGIATFRG-GGLWEGHRVEDVCTPEALAADPELVHRFYDLRRAGLA
S--VEPNGAHAALARLDREW-GELLIVTQNVDDLHERAGAQRMLHMHGALKQALCAACGERFDWADDLPP-PACAA-P---RLRPDIVFFGEVPYHMDRI
EAALAQADLFVSIGTSGAVYPAAGFVRMASAYGAATLELNLERSEGSGWFEESRLGPASQLVPEWVERMLSR-------
>tr|A0A0Q4DIE6|A0A0Q4DIE6_9SPHN NAD-dependent deacylase OS=Sphingomonas sp. Leaf10 GN=ASE59_17240 PE=4 SV=1
------------------------------------MHNIRNIVVLTGAGVSVESGIATFRG-GGLWEGHRVEDVCTPEALRADPELVHRFYDLRRAALK
Q--VAPNAAHFALAALDRAW-DELLIVTQNVDDLHERAGTQRLLHMHGALQSALCAECGIRTAHDGPLPP-TTCGA-P---ALRPGIVFFGEMPYSMDRI
GDAIGSCDLFVSIGTSGAVYPAAGFVEWANDCGAATLELNLERSGGSDQFDASRLGLASELVPAWVAEVLAQ-------
>tr|A0A0Q4GQH9|A0A0Q4GQH9_9SPHN NAD-dependent deacylase OS=Sphingomonas sp. Leaf22 GN=ASE70_11050 PE=4 SV=1
------------------------------------MQPMRNIVVLTGAGVSAESGIATFRG-GGLWEGHRVEDVCTPEALRADPRLVHRFYDLRRAALA
D--VAPNAAHVALAELERSW-GELLIVTQNVDDLHERAGTRRLLHMHGALRSALCAICGTRVAHTGPLPP-GVCGG-A---ALRPDIVFFGEIPYAMDRI
VDAIGTCDLFVSIGTSGAVYPAAGFVEWANDRGAATLELNLERSAGSGRFDESRLGPASELVPTWVAQVLAG-------
>tr|A0A0Q4KF41|A0A0Q4KF41_9SPHN NAD-dependent deacylase OS=Sphingomonas sp. Leaf32 GN=ASE83_17600 PE=4 SV=1
------------------------------------MHSVRNIVVLTGAGVSAESGIATFRG-GGLWEGHRVEDVCTPQALRADPALVHRFYDLRRAALA
G--VRPNAAHHALAALDRAW-GELLIVTQNVDDLHERAGARRLLHMHGELCSALCAACGVRVPHRDALPP-AACGA-A---ALRPDIVFFGEMPYAMDRI
VAAIGACDLFVSIGTSGAVYPAAGFVEWAKDRGAATLELNLERSAGSDRFDESRLGPAGELVPAWVDALLRA-------
>tr|A0A0F5PDR8|A0A0F5PDR8_9SPHN NAD-dependent deacetylase OS=Sphingomonas sp. SRS2 GN=WP12_08545 PE=3 SV=1
------------------------------------MSDIHNIVVLTGAGVSAESGLGTFRG-GGLWEGQRIEDICTPEALARNRDLVLDFYDQRRAALS
T--VKPNAAHEALARLDREC-GELLIVTQNVDDLHERAGTKRLLHMHGELMSALCEQCGARAGYGGSMRD-GACGTKD---VLRPDIVFFGEMPYQMELI
DQVLSRADLFLSIGTSGAVYPAAGFVRSARHHGAHTLELNLDPSEGSYFFHESRMGPASALVPAWVDEVLAA-------
>tr|A0A0Q8XL19|A0A0Q8XL19_9SPHN NAD-dependent deacylase OS=Sphingomonas sp. Root241 GN=ASE13_00130 PE=4 SV=1
------------------------------------MADIRNIVILTGAGVSAESGVATFRGP-----GHRVENVCTPQALFRDPELVHRFYDERRAKLA
S--VEPNAAHRALARLDQKW-GELLLVTQNVDDLHERAGSQRLVHMHGELKSALCAACGNRTDWEDALPP-PDCGT-P---ALRPDIVFFGEMPYHMDVI
ERALARADLFVSIGTSGAVYPAAGFVQTARHYGAATLELNLDPSEASAWFGESRMGPAGTLVPAWVDSLNRN-------
>tr|A0A0M2LRI9|A0A0M2LRI9_9SPHN NAD-dependent deacetylase OS=Sphingomonas sp. Ag1 GN=XM50_17555 PE=3 SV=1
------------------------------------MNEKRSILILTGAGISAESGLATFRG-GGLWEGHRVEDVCTPDALAADPALVHRFYDLRRAALN
A--VAPNAAHEALARLDAEW-GDLLIVTQNVDDLHERAGARRLLHMHGELRSALCPACGERRAWPDPLLP-PACAA-G---DLRPDIVFFGEMPYGMEQI
EAAIATCDLFVSIGTSGAVYPAAGFVQLANHHGARTLELNLDQSAGSGWFDESRLGPASTLVPAWVDELLAG-------
>tr|A0A0Q6AKA6|A0A0Q6AKA6_9SPHN NAD-dependent deacylase OS=Sphingomonas sp. Leaf407 GN=ASG37_13405 PE=4 SV=1
------------------------------------RTTIRNIVILTGAGISAESGIATFRG-GGLWEGHRVEDVCTPQALRADPDLVHRFYDLRRAALG
G--VTPNAAHDALARLDAAW-GELLIVTQNVDDLHERAGAKRLLHMHGELKSQLCPRCGDRRPRDGDLSP-PACAA-P---RLRPDIVFFGEMPYQMERI
EDAIAGCDLFVSIGTSGAVYPAAGFVELANHVGAATLELNLDRSAGSDRFDESRLGPASVLVPAWVDELLSA-------
>tr|C1FAB6|C1FAB6_ACIC5 Putative nicotinic acid mononucleotide:5, 6-dimethylbenzimidazole(DMB)phosphoribosyltransferase OS=Acidobacterium capsulatum (s
------------------------------------LSASDRLFVLTGAGISAESGLATFRGSDGLWNGYRVEEVATPEGWAENPELVWRFYSMRRRDA-
-LAAEPNAAHVALARLEERM-ERFYLCTQNVDDLHERAGSRRVHHMHGTLFCSRCVRCQQPFADARFYETAPVCERCGS--AVRPHIVWFGEIPRDMDGI
YRELEQATVLLVVGTSGSVYPAAGLVQVARQRGIATVYVGPERPLNAQAFGEIRLGTAVEVLPGLFGETGAH-------
>tr|F1Z509|F1Z509_9SPHN NAD-dependent deacetylase OS=Novosphingobium nitrogenifigens DSM 19370 GN=Y88_1922 PE=3 SV=1
------------------------------------MTTPHKIVILTGAGISAESGIDTFRD-GGLWEQHRVEDVATPEAFARDPELVQRFYDMRRAAVQ
T--KLPNPAHVALVRLEREWVGDVTLVTQNVDDLHERGGSLRVIHMHGEHLSAWCTACDARSRWDGPLI-RPACGVP----ALRPDIVWFGEIPYRMDEI
HEALSEADLFVSIGTSGAVYPAAGFVRLARELGLATLELNLERSQGSGWFHETRLGAASEIVPAWVDGLLDA-------
>tr|A0A0Q9PY56|A0A0Q9PY56_9ACTN NAD-dependent deacylase OS=Nocardioides sp. Soil774 GN=ASG76_06695 PE=4 SV=1
----------------------------------------MRVVVLTGAGISAESGLSTFRD-GGLWDGHDPMQVATPEAYADDPALVQRFYDERRAALE
R--VRPNAAHHALVRLEETL-DDLLVVTQNVDDLHERAGSRRVHHIHGRLRSAWCTTCGGRHEWDGPLG-EPACDAT----TLRPDIVWFGEIPYGMDLV
EQALAECDLFVSIGTSGVVYPAAAFVHWARGE---TLELNLEPSAGATDFARTLHGPATRLVPAWVEELLG--------
>tr|A0A0Q9QD45|A0A0Q9QD45_9ACTN NAD-dependent deacylase OS=Nocardioides sp. Soil777 GN=ASG88_10610 PE=4 SV=1
-------------------------------------MHTPRIVVLTGAGISAESGLPTFRDADGLWEGHDPMTVATPEAYDDDPALVHRFYDERRAALA
R--VRPNAAHRALARLEDALGDRLHLVTQNVDDLHERGGSRRVHHMHGRLRAAWCTACDERTEWDGPLGHRPSCDEP----ALRPDVVWFGEVPHGMDAI
EEALWECDLFVAIGTSGLVHPAAAFVHYAVGNGKETLELNLDASEASGDVGQSRRGPATELVPAWVDEVLGQ-------
>tr|A0A0Q9TCF1|A0A0Q9TCF1_9ACTN NAD-dependent deacylase OS=Nocardioides sp. Soil805 GN=ASG94_09160 PE=4 SV=1
------------------------------------MGGGVRIVVLTGAGISAESGLPTFRDADGLWEGHDPMTVATPEAYDDDPDLVHRFYDERRAALA
R--VRPNAAHRALARLEEALGDRLHLVTQNIDDLHERGGSRRVHHMHGRLRAAWCTSCDERTEWDGPLGHRPTCGQA----TLRPDVVWFGEVPHDMEAV
EEALWACDLFVSIGTSGLVHPAAAFVHYALGNGKQTLELNLDPSEASGDVHRSRRGPATELVPAWVDEVLAA-------
>tr|A3WFH0|A3WFH0_9SPHN NAD-dependent deacetylase OS=Erythrobacter sp. NAP1 GN=NAP1_11148 PE=3 SV=1
------------------------------------SETPSSIVILTGAGISAESGIDTFRS-GGLWEQHRIEDVATPEGFARNPDLVLGFYDARREALG
S--VKPNPAHHALARLEAEFG-DLLLVTQNVDDLHERGGSARVLHMHGELKSALCQSCETRARWDAPMSARPVCQAP----TLRPDVVWFGEMPYQMERI
YSALATCDLFVSIGTSGAVHPAAGFVQEARAYGADTLELNLEPSEGSHFFATSRHGPAGQLVPQWVDEVLG--------
>tr|A0A0N1C638|A0A0N1C638_9SPHN NAD-dependent deacetylase OS=Novosphingobium sp. AAP83 GN=IP81_05325 PE=3 SV=1
------------------------------------MQHLRNIVILTGAGISAESGIDTFRS-GGLWEQHRVEDVATPEAFARDPDLVLRFYDMRRAAIQ
T--KQPNPAHVALARLDREWKGEVLIVTQNVDDLHERGGALNVLHMHGEHLNAWCTACDARHRWTGPLI-RPSCEEP----ALRPDIVWFGEMPYRMDDI
YAALSEADLFVSIGTSGAVYPAGGLVRRARDLGAQTLELNLERSKGSAWFHETRLGPASEIVPAWVDELLGA-------
>tr|Q2GCF8|Q2GCF8_NOVAD Silent information regulator protein Sir2 OS=Novosphingobium aromaticivorans (strain DSM 12444 / F199) GN=Saro_0003 PE=3 SV=1
------------------------------------MKRPRNIVVLTGAGISAESGIDTFRG-GGLWENHRVEDVATPEAFARDPELVLRFYDMRREAIQ
T--KEPNVAHHALARLDREWRGEVLIVTQNVDDLHERGGAINVLHMHGEHLSAWCTACDARHRWTGPLL-RPACAMP----ALRPDIVWFGEIPYRMDEI
HDALAEADLFVSIGTSGAVYPAAGFVRTARELGLQTLELNLERSQGSAWFHETRLGPATETVTAWVDELLA--------
>tr|A0A0B9A874|A0A0B9A874_9SPHN NAD-dependent deacetylase OS=Novosphingobium subterraneum GN=NJ75_01687 PE=3 SV=1
------------------------------------MSTPRNIVILTGAGISAESGIDTFRG-GGLWEQHRVEDVATPEAFARDPNLVLRFYDMRREAIQ
T--KEPNAAHYALARLDREWKGEVLIVTQNVDDLHERGGALNVLHMHGEHLKAWCTSCDRRHRWTGPLL-RPTCGMQ----ALRPDVVWFGEVPYRMDEI
YRAVSEADLFVSIGTSGAVYPAAGLVRTARDLGVQTLELNLERSQGSAWFHETRLGAATEIVPAWVEELLSS-------
>tr|A0A0N1BN42|A0A0N1BN42_9SPHN NAD-dependent deacetylase OS=Novosphingobium sp. AAP93 GN=IP83_19120 PE=3 SV=1
------------------------------------MSTYRNIVILTGAGVSAESGIDTFRS-GGLWEQHRVEDVATPEGFARDPNLVLRFYDMRRAAIQ
T--KEPNPAHVALGRLEREWKGSVTLVTQNVDDLHERGGSLSVIHMHGEHLTVWCTNCDSRHRWTGPLI-RPTCSAP----YLRPDVVWFGEVPYRMDEI
FAALREADLFVSIGTSGAVYPAAGFVQNARELGAQTLELNLERSQGSQWFHETRLGPASEIVPAWVEELLGS-------
>tr|A1SUQ8|A1SUQ8_PSYIN 5,6-dimethylbenzimidazole phosphoribosyltransferase OS=Psychromonas ingrahamii (strain 37) GN=Ping_1406 PE=3 SV=1
------------------------------------FHQYKKIVVLTGAGVSAESGIQTFRDTDGLWENHKLEDVATVEGYKKDPELVLEFYNQRRRDFC
SGHKKPNAAHLALAELEEKF--EFLLVTQNIDNLHEQAG-KNIIHMHGELLKSRCPTSNQLTECFNDIETSHCCQYPS---TLRPHIVWFGEMPLGLDII
YHHLSQADLFISIGTSGTVYPAAGFVEEAKSVGAFSIELNLEASEIHSHFDQVICGKATSVVPDLVKTILAS-------
>tr|A0A0P7VWN5|A0A0P7VWN5_9RHOB NAD-dependent deacetylase OS=Oceanicaulis sp. HLUCCA04 GN=npdA PE=4 SV=1
------------------------------------ARAPGNIVMLTGAGISAESGLGTFRDKGGLWETFDWQKLATPEAFAADPHSVHAFYNARRENLV
A--AQPNDAHRALAALELLWAGDFLLVTQNIDDLHARGGSREVLHMHGELLKSRCNPCGHLFEHEHAITPDPDCGQPG---GLRPHVVWFGEMPLGLDTI
YEALAACDLFVAIGTSGTVYPAAGFVAEAKAAGAWTVELSLEPGEVSTLFDERHYGPATRIVPEWAGRI----------
>tr|F4ARG0|F4ARG0_GLAS4 Silent information regulator protein Sir2 OS=Glaciecola sp. (strain 4H-3-7+YE-5) GN=Glaag_2208 PE=3 SV=1
------------------------------------DSQRPNIVILTGAGISAESGLKTFRDNDGLWEEHAVEEVATPEAFSRNPELVYRFYNQRREQLQ
GDDVQPNAAHIALAQLEAALP--VLVITQNVDDLHERAG-KNVLHMHGELLSARCNHSHRRFIMKSPFDGTQCCSPSQ---TIRPDIVWFGEMPFHMDEI
ERAVQEADVFISIGTSGNVYPAAGLVQIANHYGAHTVELNLVPSDGNNDFLEAHYGLASDVVPSYLTQYLKG-------
>tr|F5Z7Z7|F5Z7Z7_ALTSS NAD-dependent deacetylase OS=Alteromonas sp. (strain SN2) GN=ambt_08310 PE=3 SV=1
------------------------------------MNTPPRVVVLTGAGISAESGLKTFRDNNGLWEEHSVEDVATPEAFARNPELVYRFYNERRMQLT
TDCVNPNAAHEALVTLERAL--RFTLITQNVDDLHERAG-ERILHMHGKLLSSRCVTTNKTFECKIAFDGQACCNT-A---TLRPDIVWFGEMPLYMEEI
SQDIANADIFLAIGTSGNVYPAAGFVINAKDSGAQCIELNLEPSANNWLFDESISGNATEIVPAFVTRLIKE-------
>tr|A0A010Q580|A0A010Q580_9ALTE NAD-dependent protein deacetylase, SIR2 family OS=Alteromonas sp. ALT199 GN=H978DRAFT_1512 PE=3 SV=1
-------------------------------------QSLPNIVILTGAGISAESGLKTFRDNDGLWENHSVEEVATPEAFEQNPSLVYRFYNARRAQLQ
QNDVLPNTAHTALAKLEKAL--KLTLVTQNVDDLHERGG-ESVYHMHGKLLSARCAISQETFDWRESFDHTPCCNR-V---TLRPDIVWFGEMPIYMEEI
YEALSQADVFIAIGTSGNVYPAAGFVQIAKENGAHTIEANLEPGVSNALFDESLTGPASRIVPQWVDELISK-------
>tr|K0D188|K0D188_ALTMS NAD-dependent deacetylase OS=Alteromonas macleodii (strain Black Sea 11) GN=AMBLS11_09590 PE=3 SV=1
-------------------------------------QSLPNIVILTGAGISAESGLKTFRDSDGLWENHRVEEVATPEAFEQNPSLVYRFYNARRAQLR
QDEVKPNAAHEALAKLENAF--NLMLVTQNVDDLHERGG-KSVYHMHGKLLSARCAISQQAFDWHDSFDHTPCCSR-V---TLRPDIVWFGEMPMYMEEI
YGALSKADVFIAIGTSGNVYPAAGFVQVAKESGAHTIEANLEPGVTNALFDESMTGLASHIVPKWVDDLISK-------
>tr|K6Z9M3|K6Z9M3_9ALTE NAD-dependent deacetylase OS=Paraglaciecola polaris LMG 21857 GN=npdA PE=3 SV=1
--------------------------------------SYQNVVVLTGAGISAESGLRTFRDNNGLWEDHSVQDVATPEAFTRDPELVYRFYNLRREQLQ
SPAVKPNAAHDALAEFEQSH--NVLIVTQNVDDLHERAG-QNVLHMHGELLKARCCHSQRSFNMRENFNGAVCCQPSQ---AIRPDIVWFGEMPFFMDEI
ELAVREADVFISIGTSGNVYPAAGLVQIADRYGAHTVELNLAPSDGHSYFLETHYGLASSVVAQYLAQYQKE-------
>tr|Q15U62|Q15U62_PSEA6 Silent information regulator protein Sir2 OS=Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087) GN=Patl_2058 PE=3 SV=1
------------------------------------AEGWPKIVILTGAGISAESGLKTFRDNNGLWEEHSVHDVATPEAFVRNPELVYRFYNQRRAQLQ
SDNVKPNAAHIALAQLESVLP--VLVITQNVDDLHERAG-KHVLHMHGELLSARCCHSQRRFSMKNQFDGNKCCTPSQ---NIRPDIVWFGEMPFYMQEI
ERSVQEADVFISIGTSGNVYPAASLVQIANEYGAHTVELNLAPSEGNDNFLEAYYGLASDVVPNYIKNILRV-------
>tr|S5C2X9|S5C2X9_ALTMA Uncharacterized protein OS=Alteromonas macleodii str. 'Ionian Sea UM7' GN=I635_10945 PE=3 SV=1
------------------------------------TLTNPKIVVLTGAGISAESGLKTFRDNDGLWENHRVEEVATPEAFEQNPSLVYRFYNARRAQLQ
QDDVQPNAAHQALAKLEQAL--DLMVVTQNVDDLHERGG-KSVYHMHGKLLSARCAISQQSFVWRDSFDHTPCCHR-V---TLRPDIVWFGEMPLYMDEI
YTALAQADIFIAIGTSGNVYPAAGFVQIAKESGAYTIEANLAPGATNALFDQSLTGPASQIVPEWVNELLSN-------
>tr|H5TDZ6|H5TDZ6_9ALTE NAD-dependent deacetylase OS=Glaciecola punicea DSM 14233 = ACAM 611 GN=npdA PE=3 SV=1
------------------------------------TIKHPKIVILTGAGISAESGISTFRDNKGLWENHTVEEVATPEAFARNPELVYRFYNARRQQLL
NDEVAPNPAHIALAKLQRKL--DFVLITQNVDNLHERGG-KNVIHMHGELLSAKCINSNSAVSTVDDVSSCACCDTPS---PMRPDIVWFGETPYHMKAI
QTHLQEADVFVSIGTSGNVYPAAGFVQEAQYVGAHCIELNLDPSEGQSNFTECHYGQASTLVPWFVDEICAA-------
>tr|K7A673|K7A673_9ALTE Silent information regulator protein Sir2 OS=Paraglaciecola psychrophila 170 GN=C427_2836 PE=3 SV=1
------------------------------------KLEQLKVVVLTGAGISAESGLKTFRDNNGLWEEHSIEDVATPEGFERNADLVYRFYNQRRRQLL
SPEVHPNKAHLALAKLENAL--NFTLITQNVDDLHQRAG-KNVLHMHGSLISARCLTSGSCSAIFDDLDHTDCCYPSS---NMRPDIVWFGEMPKYMQEI
ETLLYAADVFVSIGTSGTVYPAAGFVSQANHYGAYSVELNLEPSSGQNKFSENHYGPASQLVVQFVNTLLKG-------
>tr|K6YMP2|K6YMP2_9ALTE NAD-dependent deacetylase OS=Paraglaciecola arctica BSs20135 GN=npdA PE=3 SV=1
------------------------------------KLKQLKVVVLTGAGISAESGLKTFRDNNGLWEEHSIEDVATPDGFERNSELVYRFYNQRRRQLL
SPDVKPNKAHLALAKLERVL--NFTLVTQNVDNLHQKSG-KNVLHMHGSLLSARCLRSGHCSAIYSDLDHSDCCQPTN---SLRPDIVWFGEMPKFMPQI
EECLSQADIFISIGTSGTVYPAAGFVSLANQSGAHTVELNMEPSSGYNEFAEKHYGPATEIVSKFVDTLLKG-------
>tr|V1EAV5|V1EAV5_9GAMM Nad-dependent deacetylase OS=Shewanella decolorationis S12 GN=SHD_0222 PE=3 SV=1
------------------------------------SGMYQHIVVLTGAGISAESGLRTFRDQDGLWEEHHIEDVATPEGYARDTELVERFYNSRWEQLH
SGTVMPNAAHLALAKLEAEF-GQLLVVTQNIDDLHERAG-RRLLHMHGELSKGRCPRSRQTFLLREPFGPNTCCIPAQ---RLRPHVVWFGEMPLGMDRI
HDALDNCDLFIAIGTSGTVYPAAGFVDTANHHGAQTVEVNLVSPDRHSQFQYHLTGKAGDIVPKLVETILAG-------
>tr|K2JND7|K2JND7_9GAMM Sir2 family NAD-dependent protein deacetylase OS=Gallaecimonas xiamenensis 3-C-1 GN=B3C1_04255 PE=3 SV=1
------------------------------------EGQFRQIVVLTGAGISAESGIQTFRDQGGLWESHRLEEVATPEAFHRDPALVQRFYNARRAQLP
-E-VAPNAAHLALAQLEKAI--GTLLITQNIDDLHERAG-HHLLHMHGELAKARCVKSGQLFRVTEPLSEDTCCVPAQ---PLRPHVVWFGEMPLGLDRI
FHALAQCDLFVAIGTSGQVYPAAGFVDEARSQ-AYCIEINADSSHISHRFDEHRRGSATVEVPKLVAELMGR-------
>tr|A0A094JHZ4|A0A094JHZ4_9GAMM NAD-dependent deacetylase OS=Shewanella sp. YQH10 GN=HR45_05250 PE=3 SV=1
--------------------------------------MYQKIVVLTGAGISAESGLRTFRDQNGLWEDHHIEDVATPEGYMRNPELVESFYNDRWRQLQ
VPEVKPNAAHEALAKLEQAF-GDFLLVTQNVDNLHERAG-HKLLHMHGELSKGRCPRSGQIFRLHEPFGPDTCCIPAQ---RLRPHIVWFGEIPIGMDRI
HDALEECDLFIAIGTSGTVYPAAGFVDIANHHGALSVEVNLTPKERHSLFHLHYEGKASEIMPSLVDKILSG-------
>tr|H1ADJ6|H1ADJ6_9GAMM NAD-dependent deacetylase CobB OS=Shewanella livingstonensis GN=cobB PE=3 SV=1
--------------------------------------MYRQIVVLTGAGISAESGMSTFRDQHGLWEQHHIEDVATPEGYARDIELVERFYNSRWQQLH
SDDVIPNAAHLALAKLETEF-GELLVITQNVDDLHERAG-KRLLHMHGELAKGRCPQSLQTFVLREPFGVDTCCIPGK---RLRPHIVWFGEMPFGMDRI
HDALDHCDLFIAIGTSGTVYPAAGFVDSANHHGAQTVEVNLDPADRHSQFQYHFTGKAGAILPKLVDDILAG-------
>tr|A8H3I3|A8H3I3_SHEPA Silent information regulator protein Sir2 OS=Shewanella pealeana (strain ATCC 700345 / ANG-SQ1) GN=Spea_1797 PE=3 SV=1
--------------------------------------MYQQIVILTGAGISAESGLRTFRDQDGLWEEHKIEEVATPEGYANNPLLVERFYNDRWQQFH
NGSIEPNAGHTALAKLEQEF-GKLLVVTQNIDDLHERAG-RRLLHMHGELSKGRCPRSQQTFLLREAFGPKTCCIPAQ---RLRPHVVWFGEMPFGLDRI
QHALDTCDLFIAIGTSGTVNPAAGFVDTANHHGAQTVEVNLMPADRHSQFQYHLEGRASEVVPKLVDDILNG-------
>tr|B8CQZ1|B8CQZ1_SHEPW Silent information regulator protein Sir2 OS=Shewanella piezotolerans (strain WP3 / JCM 13877) GN=swp_2937 PE=3 SV=1
--------------------------------------MYQQIVILTGAGISAESGLRTFRDQDGLWEEHKIEEVATPEGYEKNPQLVEQFYNERWQQFH
NGCIEPNAGHDALAKLEREF-GKLLVVTQNIDDLHERAG-KRLLHMHGELSKGRCPRSRQTFLLREPFGPDTCCIPAQ---RLRPHVVWFGEMPIGLDRI
QHALDSCDLFIAIGTSGTVYPAAGFVDTANHHGAQTVDINLMPADRHSQFQYHLQGKASELLPKLVEQILQG-------
>tr|A3QDI1|A3QDI1_SHELP Silent information regulator protein Sir2 OS=Shewanella loihica (strain ATCC BAA-1088 / PV-4) GN=Shew_1662 PE=3 SV=1
--------------------------------------MYRQIVVLTGAGISAESGLRTFRDQDGLWEEHKIEDVATPEGYARDPEMVERFYNERWQQLH
NGKIEPNAAHKALARLEQEF-GQLLVVTQNIDDLHERAG-RRLLHMHGELTKGRCPRSHQTFLLTDHFGVNTCCIPAQ---RLRPHVVWFGEMPIGLDRI
QHALDTCDLFIAIGTSGTVYPAAGFVDTANHHGAQTVEVNLVPADRHSQFQYHLQGKASEIVPQLVEQILAG-------
>tr|A1S5I6|A1S5I6_SHEAM CobB protein OS=Shewanella amazonensis (strain ATCC BAA-1098 / SB2B) GN=Sama_1435 PE=3 SV=1
--------------------------------------MYRHIVVLTGAGISAESGIRTFRDQDGLWEEHHIEDVATPEGYERDPELVERFYNLRWEQLK
STDVKANPAHEALAQLEAEF-GDFLLVTQNVDDLHERGG-QRLIHMHGELNKGRCPRSRQTFLLREPFGPDTCCIPPQ---RLRPHIVWFGEMPFGMDRI
HDALERCDLFIAIGTSGTVYPAAGFVDIANHHGAQTVEVNLAAPDRHSQFQWHLTGKAGDIVPRLVKAVLQG-------
>tr|A0A0Q0PCG8|A0A0Q0PCG8_9GAMM NAD-dependent protein deacylase OS=Shewanella sp. P1-14-1 GN=cobB PE=4 SV=1
--------------------------------------MYRQIVVLTGAGISAESGIKTFRDQDGLWEQHHIEDVATPEGYARDIDLVERFYNSRWDNLN
SDEITVNPAHVALAKLEAEF-GKLLVITQNVDDLHERAG-KRLLHMHGELNKGRCPQSQQTFVLREPFSEDTCCIPAK---RLRPHIVWFGEMPFGMDRI
HDALDNCDLFIAIGTSGTVYPAAGFVDSANHHGAQTVEVNLAKPDRHSQFQYHLTGKAGDIVPQLVETILAG-------
>tr|Q12NU8|Q12NU8_SHEDO Silent information regulator protein Sir2 OS=Shewanella denitrificans (strain OS217 / ATCC BAA-1090 / DSM 15013) GN=Sden_1594 P
------------------------------------KKVYRRIVILTGAGISAESGLGTFRCQDGLWENHTIEDVATPEGYARDPQLVERFYNDRWLQLQ
SEAIQPNPAHEALARLGAEF-GQLLLVTQNVDDLHERSG-FAVHHMHGELNRGRCPNSSQTFVLRAPFGADTCCIPAR---RLRPDIVWFGEIPMGMDRI
HAALEACDLFIAIGTSGTVYPAAGFVDIARHHGADTVEVNLDK-TPHSQFAAHLIGKASDTVPVLVSAILAG-------
>tr|A0A0F7M4L4|A0A0F7M4L4_9GAMM NAD-dependent protein deacetylase, SIR2 family OS=Spongiibacter sp. IMCC21906 GN=IMCC21906_02812 PE=3 SV=1
------------------------------------MSQYKNIVVLTGAGISAESGIKTFRASDGLWEEHRVEDVATPEGFAANPELVHQFYNSRRRQLL
GFEVAPNPAHKALAELEARL-GNLLLVTQNIDNLHERAGSGNVLHMHGELLKMRCAYTDRIYEIDGDINEQACCGMRQ---SLRPHVVWFGEMPLYMNQI
YAALEGCELFISVGTSGNVYPAAGFVEVARSVGADTVEINLEPSATESLFAEKRYGLASVELPAFVQEILAD-------
>tr|N9VAI9|N9VAI9_9GAMM NAD-dependent protein deacetylase, Sir2 family OS=Aeromonas diversa CDC 2478-85 GN=G114_09037 PE=3 SV=1
------------------------------------ERHYQHIVILTGAGISAESGIKTFRASDGLWEEHSVEDVATPEGYARDPALVQRFYNARRAQLQ
QPSIHPNPAHYALARLERLF-GTVTLVTQNIDNLHESAGSKNLIHMHGELLKARCPQSGQTIEWKGPITESSCCQFPH---PLRPHVVWFGEMPIGLDRI
YSALARCDLFISIGTSGAVYPAAGFVHEASLSGAHSVELNLEPSEVDSQFDEKHYGLATHLVPAFVDGLLVA-------
>tr|A0A0A5MPB2|A0A0A5MPB2_AERCA NAD-dependent deacetylase OS=Aeromonas caviae GN=ACH48_17815 PE=3 SV=1
------------------------------------VQSAKHIVILTGAGISAESGIKTFRACDGLWEEHRVEDVATPEGYARDPELVQRFYNARRHQLQ
RAEIHPNPAHYALARLERLL-GRVTLVTQNIDNLHESAGSKNLIHMHGELLKARCPGSGQVIEWRGDLHQESCCQFPH---PLRPHVVWFGEMPLGLDRI
YSALAQCDLFISIGTSGAVYPAAGFVHEAGLNGAHTVELNLEPSEVGSQFDEKRYGPASLLVPAFVDELLQS-------
>tr|R1F0F0|R1F0F0_9GAMM Sir2 family NAD-dependent protein deacetylase OS=Aeromonas molluscorum 848 GN=G113_20117 PE=3 SV=1
------------------------------------MQAPKHIVILTGAGISAESGIKTFRASDGLWEEHKVEDVATPEGYHRDPVLVQGFYNARRQQLQ
QEQIHPNPAHYALARLERLY-EQITLITQNIDNLHERAGSQRLIHMHGELLRARCPVSGQVIEWRGDLHQESCCQFPQ---PLRPHVVWFGEMPLGLDRI
YGALAQCDLFISIGTSGAVYPAAGFVHEAGLNGAHTIELNLEPSELESQFDEKRYGPASLLVPAYVDELLQR-------
>tr|T0GFY6|T0GFY6_9SPHN Uncharacterized protein OS=Sphingobium quisquiliarum P25 GN=L288_15970 PE=3 SV=1
------------------------------------MDDIRNIVILTGAGISAESGLATFRGP-----GHRVEDVCTPEALARNAALVHRFYDERRAKLE
E--VAPNAAHEALAALDRQW-GELLIVTQNVDDLHERAGARRVIHMHGELRSALCAHCGKATGWPGPLPP-EGCGE-P---SLRPDIVFFGEMPYQMDAI
DDALGRADLFLSIGTSGAVYPAAGFVQTARHYGARTIELNLEPSAGSFYFHESRIGKASELVPEFVRGLLS--------
>tr|A0A086P8R0|A0A086P8R0_SPHHM NAD-dependent protein deacylase OS=Sphingobium herbicidovorans (strain ATCC 700291 / DSM 11019 / NBRC 16415 / MH) GN=cobB PE=3 
------------------------------------MDEIENIVILTGAGISAESGLATFRGP-----GHHVEDVCTPEALARNADLVHRFYDERRAKLR
D--VAPNPAHQALAALDAQW-GELLVVTQNVDDLHERAGTKRLIHMHGELRSALCAACGMAAPWIDPLPP-RRCGQ-S---SLRPDIVFFGEMPYHMEAI
DEALRRADLFVSIGTSGAVYPAAGFVQTARHAGARTLELNLEPSAGSLYFEQSRIGPASRLVPELVRELLV--------
>tr|N1MU09|N1MU09_9SPHN NAD-dependent protein deacetylase of SIR2 family OS=Sphingobium japonicum BiD32 GN=EBBID32_34940 PE=3 SV=1
------------------------------------KLDIDNIVILTGAGISAESGLATFRGP-----GHRVEDVCTPEAIARNPALVHRFYDERRAKLG
E--VAPNAAHEALAALDRAW-GELLIVTQNVDDLHERAGAKRLIHMHGALRSALCVGCGKAVAWSGPLPP-DGCGR-A---KLRPDIVFFGEMPYEMDAI
DAALRRADLFVSIGTSGAVYPAAGFVQTARHVGARTLELNLDPSAGSYYFEETRLGPASVLVPDMVRDLLG--------
>tr|A0A0Q4IGQ8|A0A0Q4IGQ8_9SPHN NAD-dependent deacylase OS=Sphingobium sp. Leaf26 GN=ASE85_15970 PE=4 SV=1
------------------------------------RSDIQNIVILTGAGISAESGLATFRGP-----GHRVEDVCTPEALARDKALVHRFYDERRAKLA
E--VQPNAAHQALAALDAAW-GDLLIVTQNVDDLHERAGAKRLIHMHGELKSALCAACGKAVAWADALPP-TGCGE-P---RLRPDIVFFGEMPYEMDRI
DAAVRDADLFVSIGTSGAVYPAAGFVQTARHVGARTLELNLDPSAGSLYFDETRLGPASQLVPDLVRALLA--------
>tr|A0A087NHS4|A0A087NHS4_9SPHN NAD-dependent protein deacetylase OS=Sphingobium sp. ba1 GN=IL54_4405 PE=3 SV=1
------------------------------------KNDIQNIVILTGAGLSAESGIPTFRSKAGVPFFHRVEDVCTPEALARNPALVHRFYDERRTTLA
T--VSPNPAHEALAALDAAW-GELLIVTQNVDDLHERAGAKRLIHMHGELQSALCAACGKAVPWTQALPP-MGCGQ-P---RLRPDIVFFGEMPYQMDAI
DEAVRHADLFVSIGTSGAVYPAAGFVQTARHVGARTLELNLDPSAGSIYFEDSRLGPASQLVPQLVRELLG--------
>tr|A4EDN1|A4EDN1_9RHOB NAD-dependent deacetylase OS=Roseobacter sp. CCS2 GN=RCCS2_03939 PE=3 SV=1
------------------------------------QTGIMKIAILTGAGVSAESGLGTFRDKDGLWTKYDLNDVATPEGFARNPALVHDFYNARRANC-
-VDATPNAAHDALAQLA-E--HEVALITQNVDDLHSRAGCLDVIHMHGQLRRALCAQCDARWDAPLVMHPDPFCAQ-A---TIRPDIVWFGEVPYHMDKI
AQAVEDAALFVAIGTSAEVYPAAGLVELARGK---TLEINLEPSARANAFDEHRFGPATEVVPAWVAALL---------
>tr|A0A0Q1ERC0|A0A0Q1ERC0_9RHOB NAD-dependent deacetylase OS=Loktanella sp. 1ANDIMAR09 GN=AL073_13800 PE=4 SV=1
----------------------------------------MKIAILTGAGISAESGLGTFRDAGGLWAQYDLNEVATPEGFARNPALVHDFYNARRANC-
-AEASPNAAHEALATLA-A--HDVTLITQNIDNLHHRAGSPDVIHMHGELMRALCAQCDARWEAPLVMSPQPFCRA-K---ATRPDVVWFGEIPYHMDAI
AHAVATANLFVAIGTSAEVYPAAGLVELAQGQ---TLEINLEPSARANAFDAHRFGPATQVVPAWVAELC---------
>tr|A0A0Q2YD65|A0A0Q2YD65_9RHOB NAD-dependent deacetylase OS=Loktanella sp. 5RATIMAR09 GN=AN191_12455 PE=4 SV=1
----------------------------------------MKIAILTGAGVSAESGLGTFRDVGGLWTQYDLNDVATPQGFARNPALVHDFYNARRTNC-
-AEAVPNAAHEALAALA-T--HDVTLITQNIDDLHSRAGSPDVIHMHGQLMRALCAACDASWDAPLVMSPQPDCGA-I---ATRPDVVWFGEIPYHMETI
AHAVTSADLFVAIGTSAEVYPAAGLVELAQGR---TLEINLEPSARANAFDDHRFGPATQIVPAWVAELR---------
>tr|A3PRS6|A3PRS6_RHOS1 Silent information regulator protein Sir2 OS=Rhodobacter sphaeroides (strain ATCC 17029 / ATH 2.4.9) GN=Rsph17029_3964 PE=3 SV=
---------------------------------------MDSIFILTGAGISAESGLGTFRDKDGLWTRYDLSRVATPEGFRADPALVHDFYNMRRKNCL
D--AAPNAAHAALARLGRDHPGEVTLVTQNVDDLHERAGSTGVIHMHGELRRALCAACGHRWPAPERMRSEPSCGRP----ATRPDIVWFGEMPYRMDEI
LERLARATLFVVIGSSGEVYPAAGFVDEAAAQGIPTLEINLEPSGRRGLFDRGLYGPATEVVPRWVAGLLRD-------
>tr|A0A0M6YD56|A0A0M6YD56_9RHOB NAD-dependent protein deacylase OS=Jannaschia donghaensis GN=cobB_1 PE=3 SV=1
------------------------------------GRDMVNIVVLSGAGLSAESGLGTFRDVDGLWTRYDLAQVATPEGFARDPALVHDFYNARRANM-
-ADAAPNAAHVALAQLSL---PGVALVTQNIDDLLDRAGATDVIHMHGALSRALCAACDARWDAPAVMTAKPACGV-A---ATRPDVVWFGEMPYAMARI
EDLLARADLFVSIGTSGTVYPAAGFVDLARRAGARTLELNLEAS--GGAFDAVRTGPATEVVPGWVAEIATG-------
>tr|A0A0K9UY91|A0A0K9UY91_VIBCL NAD-dependent deacetylase OS=Vibrio cholerae 2740-80 GN=VC274080_021568 PE=3 SV=1
------------------------------------SLPYRHVVILTGAGISAESGIQTFRAQDGLWENHRIEDVATPEGFQRDPDMVLEFYNQRRRKLL
SDAIQPNPAHLALGKLEKEL-GSVTVITQNIDNLHERGGSQNIIHMHGELLKARCPESNQTVEQKEDIRHGHCCQMPA---QMRPHIVWFGEMPLRMGDI
YAALEQADLFVSIGTSGVVYPAAGFVHDARMHGAHTIEINLEPSAVESEFAEKRYGKASIEVPRLVEEILAA-------
>tr|A0A0E9MMP3|A0A0E9MMP3_9SPHN NAD-dependent protein deacylase OS=Sphingomonas changbaiensis NBRC 104936 GN=cobB PE=3 SV=1
------------------------------------MRRIETIVVLTGAGVSAESGLATFRGP-----GHRVEEVCTPQALARDPALVHAFYDARRARLA
E--VEPNAAHKALARLDAAW-GELLIVTQNVDDLHERAGAKRLLHMHGELKSALCAGCEARMPWDRPMSPAPRCGA-A---KLRPDIVFFGEMPYQMDRI
DAALSRADLFVSIGTSGAVYPAAGFVQTARHCGAWALELNLEPSAGSYLFSESRMGPAGEQVPAWVDEVLKR-------
>tr|M4S0Z0|M4S0Z0_9SPHN NAD-dependent deacetylase OS=Sphingomonas sp. MM-1 GN=G432_02005 PE=3 SV=1
------------------------------------MRDIETILVLTGAGISAESGLATFRG-DGLWEGHRVEEICTPQALARNPALVQNFYDMRRAALA
R--VVPNAAHHALARLDAEW-GELLIVTQNVDDLHERAGARRMLHMHGELKSAFCRECGGRVRWEGTLAD-PLCGGEG---ALRPDIVFFGEMPYQMERI
EEALAEADLFVSIGTSGAVYPAAGFVQTARYRGAETLELNLDPSAGSHIFHESRVGPAGLLVPEWVDEMLGR-------
>tr|R7KI64|R7KI64_9BURK Transcriptional regulator Sir2 family OS=Sutterella sp. CAG:521 GN=BN692_00920 PE=4 SV=1
------------------------------------RGERPCIFILSGAGLSVESGIPTYRGESDPKNDS---ASLSRGYMRSLPERVFEAANQRIHDF-
-DACEPNAAHKAIAKFIKKY-ADIVHVTQNIDSLCEEAG-TAVFHLHGSLNRSLCQKCGTVFPR------GPKCRAQFS--AVRPDVVLFGETPHGLDWI
MPYLKEVDIFIAIGTSGTVYPAADFVTIAAS-GAPIRMLLNKE-PREMQFNCSMLGKATGIVPMVLKEVGQL-------
>tr|U1UDR4|U1UDR4_PSEME NAD-dependent deacetylase OS=Pseudomonas mendocina EGD-AQ5 GN=O203_05040 PE=3 SV=1
------------------------------------SMPHPNIVILTGAGISAESGIRTFRAADGLWEDHRIEEVATPEGFARNPSLVQRFYDMRRAQLR
DPAIAPNAGHLALAELEDGW-GEFLLVTQNVDNLHERAG-KRLLHMHGELQSMLCSNSQQRFPLQDDMPVSTCCGLVG---TLRPDIVWFGEMPYHMERI
YDALEQCELFVSIGTSGHVYPAAGFVEQARHA-AHTLEINLEPSQGHSLFAEKRYGPATEQLPRWVTELLAG-------
>tr|C8ND64|C8ND64_9GAMM Transcriptional regulator, Sir2 family OS=Cardiobacterium hominis ATCC 15826 GN=cobB PE=3 SV=1
-------------------------------------MPAKRIVILTGAGISAESGIATFRASDGLWENHRVEDVATPEGFARNPKLVHDFYNARRARLH
DADVQPNAAHMAIAKLQRALP--VTLVTQNVDDLHERAG-PEVLHMHGSLLALRCLYCDSVADNWHDDSREPTCKRAG---GMRPDIVWFGEMPYYMETI
EARLAECTHFAAIGTSGHVYPAAGFAALARHYGAEISEINLEPSQGAAQFHHVYSGKATVEVPRWVDSMLN--------
>tr|A4W9D4|A4W9D4_ENT38 Silent information regulator protein Sir2 OS=Enterobacter sp. (strain 638) GN=Ent638_1635 PE=3 SV=1
------------------------------------GMEKPRVVVLTGAGISAESGIRTFRAADGLWEEHRVEDVATPEGFARDPALVQAFYNARRRQLQ
SPEIAPNAAHLALAKLEQEL-DRFLLVTQNIDNLHERAGNRNVIHMHGELLKVRCAWSGQVLDWTGDITPDHCCQFPS---PLRPHVVWFGEMPLGMDDI
YSALAMADIFIAIGTSGHVYPAAGFVHEAKLHGAHTVELNLEPSQVGSEFEEKQYGLASAVVPDFIEKLLKG-------
>tr|L0M767|L0M767_ENTBF NAD-dependent protein deacetylase, SIR2 family OS=Enterobacteriaceae bacterium (strain FGI 57) GN=D782_2635 PE=3 SV=1
------------------------------------HMDKPRVLVLTGAGISAESGIRTFRAADGLWEEHRVEDVATPEGFQRDPALVQAFYNARRRQLQ
QPEIQPNAAHIALARLEEAL-DNFMLVTQNIDNLHERAGSKNVLHMHGELLKVRCTQSGQVLDWTDDVTPDHCCQFPA---PLRPHIVWFGEMPFEMDHI
YLALSMADIFIAIGTSGHVYPAAGFVHEAKLHGAKTVELNLEPSQVGSEFEEKYYGLASEVVPAFVDQLLQK-------
>tr|Q2BKC9|Q2BKC9_NEPCE NAD-dependent deacetylase OS=Neptuniibacter caesariensis GN=MED92_02126 PE=3 SV=1
-------------------------------------MAIESIVVLTGAGISAESGIRTFRAADGLWEDHRVEDVATPEAFVRDPRLVHRFYNERRNQLL
SDEIKPNAGHKALAELEAKF-GSFLLVTQNIDNLHERAGSKNLLHMHGELLNLRCSDSGVVYRIEEESLPEQCCGSSG---NLRPDIVWFGEMPMYMDRI
YTALEGCDLFISIGTSGHVYPAAGFVEVANAAGALTVELNLEPSRVESAFDHHIYGQGTEVVPEFVNDIIRQ-------
>tr|M4U349|M4U349_9GAMM 5,6-dimethylbenzimidazole phosphoribosyltransferase OS=Psychromonas sp. CNPT3 GN=PCNPT3_04380 PE=3 SV=1
------------------------------------MKNYKKIVVLTGAGISAESGVRTFRAQDGLWEDHRVEDVATLEGYLKNPQFVLNFYNNIRQKYC
LENIKANTAHQALAKLEQEF--DFLLITQNIDNLHEQAG-KNIIHMHGELLKARCTHCMQVFDWDKEMHVHQNCQTKG---SMRPNIVWFGEIPFEMDTI
YDALFEADLFIAIGTSGHVYPAAGFAEEAKQAGAYSIELNVTASQQQSNFDKIILEKASISVPLLVDAIVAK-------
>tr|H2FW12|H2FW12_OCESG Sir2 family NAD-dependent protein deacetylase OS=Oceanimonas sp. (strain GK1) GN=GU3_10190 PE=3 SV=1
------------------------------------DVQKGNIVILTGAGISAESGIRTFRAADGLWEEHRIEDVATPEGYQRDPALVQRFYNQRRELLQ
-T-VEPNAAHYALARLEAEW-EQVTIVTQNIDDLHERAGSHNVLHMHGELLKARCPHSNQTISWTGPLHTTHCCQFPE---PLRPHVVWFGEMPLLLDRI
YQALSEASLFIAIGTSGNVYPAAGFVHEAAMHHAHTLEINLAPSEVQDNFDEHRYGPATRVVTDYVNELLAG-------
>tr|K0C6F5|K0C6F5_CYCSP NAD-dependent deacetylase OS=Cycloclasticus sp. (strain P1) GN=Q91_2037 PE=3 SV=1
------------------------------------MKNAKSIVILTGAGVSAESGIKTFRASDGLWEEHRIEEVATPEGFARNPALVHRFYNMRRQQLL
SGEVKPNEAHLAIAELEKNN-LSVLVVTQNIDNLHERAG-KNIIHMHGELLKCFCKQSEKRFTVYENLNEDECCGQQK---TLRPDIVWFGEMPYQMDEI
YRAIIECDLFLSIGTSGNVYPAAGFVEMANQA-AHTVELNLEPSQVESEFKEKIYGPASEVVASYLRQLM---------
>tr|I3DDE2|I3DDE2_9PAST Transcriptional regulator, Sir2 family OS=Pasteurella bettyae CCUG 2042 GN=HMPREF1052_1697 PE=3 SV=1
------------------------------------MPKLPKIVVLTGAGISAESGIRTFRSEDGLWEEHHIEDVATPEGYARNPQLVREFYNGLRHKLF
DPKIQPNAAHLALAKLDEKF--NLLIVTQNIDNLHERAG-KNVIHMHGSLLELRCEHSGKVYAWEKEWTAQTCCHTPQ---PLRPNIVWFNEMPLAMDRI
DEEIRDCLYFISIGTSGNVYPAAGFVQEANFNGAKTIELNLEPSKGRAAFRIGHYGPATEVVPKFVEEMLFL-------
>tr|D0IAC1|D0IAC1_GRIHO NAD-dependent protein deacetylase of SIR2 family OS=Grimontia hollisae CIP 101886 GN=VHA_002698 PE=3 SV=1
------------------------------------QFPYKNIVILTGAGISAESGIRTFRAQDGLWEEHHIEDVATPEGFARNPALVQTFYNQRRRQLQ
SG-VAPNPAHEALAKLEREL-GSVTVVTQNIDNLHERAGSDNVIHMHGELLKARCSGSHQVLDWKEDIMADHCCQIPS---AMRPHVVWFGEMPLHMDKI
HAALVNADLFISIGTSGSVYPAAGFVHEAAIHGARTIEVNLEPSAVESEFDEKRYGKASVLVPELVEEILAL-------
>tr|V5CMU9|V5CMU9_ENTCL NAD-dependent deacetylase OS=Enterobacter cloacae S611 GN=cobB PE=3 SV=1
------------------------------------VMEKPRVVVLTGAGISAESGIRTFRAADGLWEEHHVEDVATPEGFARNPQLVQRFYNDRRRQLQ
QPEIAPNAAHLALAKLEEAL-DRFLLITQNIDNLHERAGNQHIIHMHGELLKVRCSQSGQVLEWTGDVTEEHCCQFPA---PLRPHVVWFGEMPLGMDEI
YSALAMADLFIAIGTSGHVYPAAGFVHEAKLHGAHTVELNLEPSQVGSEFEEKQYGLASEVVPAFVDKLLKG-------
>tr|W9VRC4|W9VRC4_9GAMM NAD-dependent deacetylase OS=Nitrincola sp. AK23 GN=cobB_2 PE=3 SV=1
------------------------------------LMQYRNIVVLTGAGISAESGIKTFRDSNGLWEEHRIEDVATPEGFARDPELVYQFYNQRRAQLK
QAEIKPNAAHLALAEFEQRM--RFTLITQNVDNLHQRAG-LNILTMHGELQSALCLTSGKAQTWTEDLTNQSCCQPPS---AMRPNIVWFGEVPYGLDEC
FECVSESDVFISIGTSGKVYPAAGFMSVAKTAGAHTVELNMEQT--SHTFDEGIYGPASKVVVEYLNSIRI--------
>tr|G5M4P6|G5M4P6_SALET NAD-dependent protein deacetylase of SIR2 family OS=Salmonella enterica subsp. enterica serovar Gaminara str. A4-567 GN=SeGA_27
------------------------------------MMENPRVLVLTGAGISAESGIRTFRAADGLWEEHRVEDVATPEGFARNPGLVQTFYNARRQQLQ
QPEIQPNAAHLALAKLEEAL-DRFLLVTQNIDNLHERAGNRNIIHMHGELLKVRCSQSGQILEWNGDVMPEHCCQFPA---PLRPHVVWFGEMPLGMDEI
YMALSMADIFIAIGTSGHVYPAAGFVHEAKLHGAHTVELNLEPSQVGSEFEEKHYGPASQVVPEFVDKFLKG-------
>tr|A0A085GF14|A0A085GF14_9ENTR SIR2 family NAD-dependent protein deacetylase OS=Buttiauxella agrestis ATCC 33320 GN=cobB PE=3 SV=1
------------------------------------AMEKPRVVVLTGAGISAESGIRTFRATDGLWEEHRVEDVATPEGFARDPELVQAFYNARRRQLQ
QAEIKPNAAHLALARLEEEL-DHFLLVTQNIDNLHERAGNKNIIHMHGELLKVRCAQSGQVIEWKGDVTPQHCCQLSS---PLRPHVVWFGEMPLGMDEI
YQALATADYFIAIGTSGHVYPAAGFVHEARLQGAHTVELNLEPSQVGSEFEEKFYGLASEVVPEYVERLLKG-------
>tr|A0A089UJX7|A0A089UJX7_9ENTR NAD-dependent deacetylase OS=Cedecea neteri GN=LH23_13885 PE=3 SV=1
------------------------------------AMDRPRVVVLTGAGISAESGIRTFRAADGLWEEHRVEDVATPEGFARDPALVQRFYNDRRRQLQ
QPEIQPNAAHLALAKLEEAL-DHFVLVTQNIDNLHERAGSKNVIHMHGELLKVRCASSGQVLDWQDDITPEHCCQISS---ALRPHVVWFGEMPLGMDEI
YQAIATADYFIAIGTSGHVYPAAGFVHEARLQGAHTVELNLEPSQVGSEFEEKHYGLASLVVPEFVDKLLKG-------
>tr|K8CP42|K8CP42_CROSK NAD-dependent protein deacetylase of SIR2 family OS=Cronobacter sakazakii 696 GN=BN128_438 PE=3 SV=1
------------------------------------VMNKPVVVVLTGAGISAESGIRTFRAADGLWEEHRVEDVATPEGFARNPQLVQEFYNARRRQLQ
QPEIKPNAAHLALARLEEAL-DRFLLVTQNIDNLHERAGSKNVVHMHGELLKVRCSQSGQVLEWTGDVTPGHCCQFPA---PLRPHVVWFGEMPLGMDRI
YEALARADVFIAIGTSGHVYPAAGFVHEAKLQGAHTVELNLEPSQVGSEFEEKHYGLASQVVPEYVEKLLKG-------
>tr|X6QEZ3|X6QEZ3_9ENTR Transcriptional regulator, Sir2 family OS=Providencia alcalifaciens F90-2004 GN=HMPREF1562_0642 PE=3 SV=1
------------------------------------SMQNINVVVLTGAGISAESGIQTFRSADGLWEEHRVEDVATPEGFARDPQLVQRFYNERRRQLQ
QEDIQPNAAHYALAKLEHAL-DRFLLVTQNIDNLHERAGSKRVVHMHGELLKVRCNWSNQVLEWKGDLSVEHCCQFPQ---PLRPHIVWFGEMPFEMDRI
YQALGEATLFISIGTSGHVYPAAGFVHEARLQGAHTVQLNLEPSQVESEFEERHYGLASKVVSDYVDDLLAK-------
>tr|B5JSY1|B5JSY1_9GAMM CobB protein OS=gamma proteobacterium HTCC5015 GN=cobB PE=3 SV=1
-------------------------------------MRYQNIVILTGAGVSAESGLNTFRGADGLWENHRLEEVATPEAFARDPQLVQRFYNQRRHQLN
-S-VVPNAAHIAIAQLQREH-GAVFLITQNVDDLHERAG-EFVLHMHGELKRARCQSTGKVVPIEDDLSPDTVCAASG---CLRPNVVWFGEMPIGMDAI
EVALNQADLFISIGTSGNVYPAAGFVQLARQV-AHTVELNLEPSQGANLFQEHHHGMASEVVPAYVAELLAG-------
>tr|D4BSU2|D4BSU2_PRORE Transcriptional regulator, Sir2 family OS=Providencia rettgeri DSM 1131 GN=PROVRETT_05361 PE=3 SV=1
-------------------------------------MKNVNIVVLTGAGISAESGIQTFRSADGLWEEHRVEDVATPEGFERNPKLVQRFYNERRRQLQ
QENIKPNAAHYALAQLEEIF-DRFLLITQNIDNLHERAGSQRVIHMHGELLKVRCNWSNQVLEWKGDLSVDHCCQFPQ---PLRPHIVWFGEMPIGMDYI
YQSLESATIFISIGTSGHVYPAAGFVHEAKLHGAHTVELNLEPSQVESEFDEKHYGLASKVVVEYINKLITE-------
>tr|I2BAB7|I2BAB7_SHIBC NAD-dependent deacetylase OS=Shimwellia blattae (strain ATCC 29907 / DSM 4481 / JCM 1650 / NBRC 105725 / CDC 9005-74) GN=cobB P
------------------------------------GMEKPRVVVLTGAGISAESGIRTFRAADGLWEEHRVEDVATPEGFERDPALVQAFYNARRAQLS
LPEIKPNAAHYALAELERAL-GNLLLVTQNIDNLHERAGSRNIIHMHGELLKVRCAWSGQVLDWTGDVQPDHCCQFPA---RLRPHVVWFGEMPLGMDEI
YQAIADADIFIAIGTSGHVYPAAGFVHEARLQGAHTVELNLEPSQVGSEFEEKHYGLASEVVPEYVRKIIAE-------
>tr|A0A0F2P6D6|A0A0F2P6D6_9GAMM NAD-dependent deacetylase OS=Gammaproteobacteria bacterium BRH_c0 GN=VR73_00640 PE=3 SV=1
------------------------------------GEEYQRIVILTGAGISAESGIKTFRASDGLWEEHRIEDVATPEGFAANPRLVHQFYNLRRQQLL
GDAVQPNAAHLALARLEAEF-GEVLLVTQNIDNLHERAGCRNVIHMHGELLKSRCARSGELFPVGGDINVDDCCNLAG---SLRPHVVWFGEIPLLMDEI
YNALHQCDLFVAIGTSGNVYPAAGFVREAVAAGAHTLEINLEPSAVQSMFAEKRRGLASEQVPRLVGELLSV-------
>tr|W1IXU2|W1IXU2_9ENTR NAD-dependent deacetylase OS=Xenorhabdus szentirmaii DSM 16338 GN=npdA PE=3 SV=1
------------------------------------KIKNPHVVVLTGAGISAESGIRTFRASDGLWEEHLVEDVATPEGFQRDPDMVQAFYNARREQLQ
QLDIKPNAAHDALAELEQRL-DNFLLVTQNIDNLHERAGSQRVLHMHGELLKVRCCQSGQVIEWKTELTTEHCCQFPS---QLRPHVVWFGEMPLGMEQI
YTALSKADIFIAIGTSGHVYPAAGFVHEAKLSGAHTVELNLEPSQVESLFDEKHYGHASKVVAQYVQSLIQQ-------
>tr|D3V800|D3V800_XENBS Putative enzyme with DHS-like NAD/FAD-binding domain OS=Xenorhabdus bovienii (strain SS-2004) GN=cobB PE=3 SV=1
------------------------------------KIKRPRVVVLTGAGISAESGIRTFRSSDGLWEEHRVEDVATPEGFQRDAELVQAFYNARRKQLQ
QPEIQPNAAHYALVELEQQL-DNFLLVTQNIDNLHERAGSRRVLHMHGELLKARCCQSGQMIEWKTELTTEHCCQFPS---PLRPHVVWFGEMPLGMEQI
YSALADADLFIAIGTSGHVYPAAGFVHEAKLSGALTIELNLEPSQVESLFDEKHYGHASKIVTQYVQSLLQQ-------
>tr|A0A068R254|A0A068R254_9ENTR NAD-dependent deacetylase OS=Xenorhabdus poinarii GN=npdA PE=3 SV=1
------------------------------------KIENPRVVVLTGAGISAESGIRTFRSSDGLWEEHRVEDVATPEGFLRDPEMVQAFYNARREQLQ
QQEIRPNAAHYALAELERQL-ERFLLVTQNIDDLHERAGSHRVLHMHGELLKVRCCQSGQVIEWTANLTVDHCCQFPA---PLRPHVVWFGEMPLGMEQI
YAALAEADIFIAIGTSGHVYPAAGFVHEAKLSGAHTVELNLEPSQVESIFDEKHYGYASNIVTEYVQSLLHQ-------
>tr|A0A068QT77|A0A068QT77_9ENTR NAD-dependent deacetylase OS=Xenorhabdus doucetiae GN=npdA PE=3 SV=1
------------------------------------KTEKPYVVVLTGAGISAESGIRTFRSSDGLWEEHRVEDVATPEGFQRDPDLVQAFYNARREQLR
QPQIQPNAAHDALVELEHEL-DHFLLVTQNIDDLHERAGSHRVLHMHGELLKARCCQSGQVVEWVTDLTMEHCCQFPS---PLRPHVVWFGEMPLGMEQI
YSALADADIFIAIGTSGHVYPAAGFVHEAKLSGAHTVELNLEPSQVENLFDEKHYGHASKIVTQYVQSLIQQ-------
>tr|W1JAI5|W1JAI5_9ENTR NAD-dependent deacetylase OS=Xenorhabdus cabanillasii JM26 GN=npdA PE=3 SV=1
------------------------------------KIKNPHVVVLTGAGISAESGIRTFRSSDGLWEEHRVEDIATPEGFKRDPELVQEFYNARREQLQ
QPEIQPNAAHYALAKLEQEL-DNFLLVTQNIDNLHERAGSQRIIHMHGELLKVRCCQSGQVIEWTSKLSMEHCCQFPS---LLRPHVVWFGEMPLGMEQI
YSALAKADIFIAIGTSGHVYPAAGFVHEAKLSGAHTVELNLEPSQVESMFDEKHYGNASQIVTRYIQSLLQQ-------
>tr|D3VID0|D3VID0_XENNA Putative enzyme with DHS-like NAD/FAD-binding domain OS=Xenorhabdus nematophila (strain ATCC 19061 / DSM 3370 / LMG 1036 / NCIB
------------------------------------KIEKTHVVVLTGAGISAESGIRTFRSSDGLWEEHRVEDVATPEGFQRDPELVQAFYNARREQLQ
QPEVVPNPAHYALAELEQVL-DHFLLVTQNIDNLHERAGSQRVLHMHGELLKVRCCQSGQVIEWTHELTMDHCCQFPA---QLRPHVVWFGEMPLGMESI
YAALNEADIFIAIGTSGHVYPAAGFVHEAKLSGAHTVELNLEPSQVESLFDEKHYGYASKTVTEYIQSLIHQ-------
>tr|I2JQ03|I2JQ03_9GAMM NAD-dependent deacetylase OS=gamma proteobacterium BDW918 GN=DOK_00797 PE=3 SV=1
-------------------------------------MAYQRVVVLTGAGISAESGIKTFRAADGLWEEHRVEDVATPEGFAANPTLVQRFYNERRRQLL
SAAVSVNPAHLALAEFEKKF-GELLLVTQNIDDLHERAGSQKLIHMHGELLKMQCSYSGVVYPIATDISADACCGLRG---GLRPHIVWFGEMPLGMDEI
YTALEQCDLFIAVGTSGNVYPAAGFVQAAASVGAHTIEVNLEPSAVQSAFSETRYGLASVEVPRLLNELLAA-------
>tr|A9HK18|A9HK18_GLUDA Putative NAD-dependent deacetylase OS=Gluconacetobacter diazotrophicus (strain ATCC 49037 / DSM 5601 / PAl5) GN=npdA PE=3 SV=1
------------------------------------ERPWERIVVLTGAGISRESGLETFRDGDGLWSRYAIEDVCTPHAFHRDPLLVDRFYNDRRAEL-
-WRVRPNDAHLALARLEHAAAGEILIVTQNIDDLHERAGSRNVVHMHGELLRVRCTACGATPDWQENCLPQPICHR-P---ALRPDVVWFGEIPLHMERI
QAALDRCDRFVSIGTSGTVYPAAGFVAQV-RDHADTLDINLEAPAVPTAFERSMVGAATRMVPRWVDEVLAG-------
>tr|A0A0N0MFK5|A0A0N0MFK5_9PROT Silent information regulator protein Sir2 OS=Komagataeibacter intermedius AF2 GN=GLUCOINTEAF2_0200555 PE=3 SV=1
---------------------------------------MQRIVVLTGAGISQESGLQTFRGTDGLWNHERIEDICTPQGFRRDPMRVDRFYNGLRAQL-
-PGVHPNAAHLALADLERAGEGQVTVITQNIDDLHERAGSRNVIHMHGELLRLRCTSCHATPQWRTDCFPDPACGQ-P---TLRPDIVWFGEMPYHMDSI
ARYLAECDLFVAIGTSGVVYPAAGFVDSV-AGHADTMLFNLEVPPGPSAFDQAIVGPATRTVPAWTRDLLEA-------
>tr|A0A070A1S2|A0A070A1S2_9PROT NAD-dependent deacetylase OS=Komagataeibacter rhaeticus AF1 GN=GLUCORHAEAF1_13985 PE=3 SV=1
---------------------------------------MRHIVVLTGAGISQESGLQTFRGPDGLWNHERIEDICTPQGFRRDPLRVDRFYNGLRAQL-
-ADVQPNAAHRALAELEQAATGQVTIVTQNIDDLHERAGSRNVIHMHGELLRLRCTHCHATPPWHTDCYPDPHCGQ-P---ALRPDIVWFGEMPHHMDAI
ARHLAACDLFVAIGTSGVVYPAAGFVENV-ADHADTMLFNLDAPQGPSAFEQVILGPATRTVPIWTHDLMAA-------
>tr|A0A0D6MV11|A0A0D6MV11_ACEAC NAD dependent deacetylase OS=Acetobacter aceti NBRC 14818 GN=Abac_014_119 PE=3 SV=1
---------------------------------------MERIVILTGAGISRESGLATFRDEAGVWSRVRLEDVCTPEGFARNPDQVDAFYNHRRQEL-
-QHVAPNAAHRALAELEQAY-DAFLLITQNIDDLHERAGSHNVVHMHGELLQLRCLSCGATPTWHQDCTRAPECGA-Q---ALRPDVVWFGEMPLHMEGI
MDAIARCDCFVAIGTSATVYPAAGFTELA-TNHAHTVELNLAPSGKAGLFDEAAYGPATSVVPRFVKSRLAA-------
>tr|D5QD12|D5QD12_KOMHA Silent information regulator protein Sir2 OS=Komagataeibacter hansenii ATCC 23769 GN=GXY_05091 PE=3 SV=1
------------------------------------GGPMQRIVVLTGAGISQESGLQTFRGEDGLWNHERIADICTPEGFTRDPMRVDRFYNGLRAGL-
-ADVQPNAAHRALAHMEECATGEILIVTQNIDDLHERAGSRDVVHMHGELMRVRCTACGATPSWHADCLPQPACHR-P---QLRPDIVWFGEIPYHMDRI
AAALQACDLFVAIGTSGVVYPAAGFVQQA-SPHADTMEFNLQPSAGTDLFDQTVLGPATKTVSRWVRDVTGT-------
>tr|H3MKL3|H3MKL3_RAOOR NAD-dependent deacetylase OS=Raoultella ornithinolytica 10-5246 GN=HMPREF9690_01766 PE=3 SV=1
------------------------------------TVDKPRVVVLTGAGISAESGIKTFRAADGLWEEHRVEDVATPEGFARDPALVQAFYNARRRQLQ
SPEIAPNAAHQALARLEAAL-DRFVLVTQNIDNLHERAGNRRVIHMHGELLKVRCSWSGQVLEWTGDVTAEHCCQFPA---PLRPHVVWFGEMPLGMDDI
YNALADADIFIAIGTSGHVYPAAGFVHEARLQGAHTVELNLEPSQVGSEFAEKHYGLASEVVPAFVDRLLKD-------
>tr|V3T0V8|V3T0V8_9ENTR Uncharacterized protein OS=Serratia sp. ATCC 39006 GN=Ser39006_03087 PE=3 SV=1
------------------------------------DVKKPRVVVLTGAGISAESGIRTFRAVDGLWENHRVEDVATPEGFQRDPQQVQNFYNERRRQLQ
QPEVMPNAAHLALANLEAML--NFLLVTQNIDNLHERAGSKRVIHMHGELLKVRCSQSGQVFDWPGDLSVEHCCQFPA---PLRPHVVWFGEMPLEMDHI
YHALAKADYFVAIGTSGHVYPAAGFVHEAHSHGAYTIEMNLEPSQVESQFDEKIYGPASQIVPEFVGAWLSR-------
>tr|J7L0P6|J7L0P6_PECCC NAD-dependent deacetylase OS=Pectobacterium carotovorum subsp. carotovorum PCC21 GN=PCC21_025840 PE=3 SV=1
------------------------------------EVKKPRVVVLTGAGISAESGIRTFRAADGLWEEHRVEDVATPEGFQRNPELVQEFYNARRRQLQ
QPEIVPNAAHLALANLEAML--NFLLITQNIDNLHERAGSKRIIHMHGELLKVRCSQSGQIVEWTDDLAAGHCCQFPA---PLRPHVVWFGEMPLHMDKI
YHALSQADYFIAIGTSGHVYPAAGFVHEAHSHGAYTLELNLEPSQVESQFDEKIYGPASTVVPEFVAAWLTR-------
>tr|U6ZA28|U6ZA28_9ENTR Deacetylase of acetyl-CoA synthetase, NAD-dependent OS=Dickeya solani D s0432-1 GN=A544_2577 PE=3 SV=1
------------------------------------NVNKPRVVVLTGAGISAESGIRTFRASDGLWEEHRVEDVATPEGFHRDPQTVQNFYNQRRRQLQ
QPEITPNAAHLALAELEAAL--HFLLVTQNIDNLHERAGSKRIIHMHGELLKVRCSQSGQIFEWTGDVSVDHCCQFPA---PLRPHVVWFGEMPLEMEHI
YHALSEADLFVAIGTSGNVYPAAGFVHEARVNGAHTVELNLEPSQVQNQFDEHIYGPASKVVVEFVRTWLAH-------
>tr|C6C3S4|C6C3S4_DICDC Silent information regulator protein Sir2 OS=Dickeya dadantii (strain Ech703) GN=Dd703_1622 PE=3 SV=1
------------------------------------NVKTPRVVVLTGAGISAESGIRTFRASDGLWEEHRVEDVATPEGFYRDPQTVQNFYNQRRRQLQ
QPEIAPNPAHLALAEMEKAL--HFLLVTQNIDNLHERAGSKRIVHMHGELLKVRCSQSGQVFEWKGDVAADHCCQFPA---PLRPHVVWFGEMPLEMDRI
YHALSEADVFIAIGTSGHVYPAAGFVHEAHSHCAHTVELNLEPSQVQSQFDEHIYGPASKVVPAFVTQWLAR-------
>tr|A0A0G4JZY9|A0A0G4JZY9_9ENTR NAD-dependent protein deacetylase of SIR2 family OS=Brenneria goodwinii GN=BN1221_03744 PE=3 SV=1
------------------------------------EVKKPRVVVLTGAGVSAESGIRTFRAADGLWEEHRVEDVATPEGFQRDPELVQAFYNARRRQLQ
QPEIKPNAAHLALANLEASL--NFLLVTQNIDNLHERAGSRRIVHMHGELLKVRCCRSGQVFDWTGDLSAEHCCQFPA---PLRPHIVWFGEMPLEMDKI
YQALSQADYFIAIGTSGHVYPAAGFVQEARTHGAYTVELNLEPSQVESLFDEKNYGPASVVVPEFVSGCLTH-------
>tr|A0A0A0Z546|A0A0A0Z546_9ENTR NAD-dependent deacetylase OS=Pantoea sp. PSNIH1 GN=PSNIH1_12010 PE=3 SV=1
------------------------------------AHPLPRVVVLTGAGISAESGIRTFRASDGLWEEHRIEDVATPEGFRRDPALVQRFYNIRRQQLQ
QPEIQPNAAHLALAELEQAL-DNFLLVTQNIDNLHERAGSQRVPHMHGELLKVRCEESGQVVAWHRDVTADTCCQFPA---RLRPHVVWFGEMPLGMEEI
YEAMQQVDLFIAIGTSGHVYPAAGFVHEATLQGAHTVELNLEPSQVGNEFAEGKYGLASEEVPAFVQRLLQS-------
>tr|A0A0L7TI20|A0A0L7TI20_9ENTR NAD-dependent deacetylase OS=Erwinia iniecta GN=NG42_03560 PE=3 SV=1
------------------------------------AHPLPRVVVLTGAGISAESGIRTFRASDGLWEEHRVEDVATPEGFARDPALVQAFYNARRQQLQ
QPDIQPNAAHQALAELESVL-DSFLLVTQNIDNLHERAGSERVIHMHGELLKVRCSMSGQVLDWTEDVKPGHCCQFPA---VLRPHVVWFGEMPLEMDEI
YQAIEQADYFVAIGTSGHVYPAAGFVHEAKLQGAHTVELNLEPSQVGSEFEEKKYGPASQVVPLYVRTFLLG-------
>tr|A0A014M8Q1|A0A014M8Q1_9ENTR NAD-dependent deacetylase OS=Erwinia mallotivora GN=BG55_16545 PE=3 SV=1
---------------------------------------MPRVVVLTGAGISAESGIRTFRAADGLWEDHKVEEVATPEGFAQDPQKVQAFYNARRRHLQ
QPEIAPNAAHLALAELEAAL-DHFLLVTQNIDNLHERAGSRNIIHMHGELLKLRCVISGQVVNWQDDVNPDHCCQFPS---VLRPHIVWFGEMPLQMDEI
YTALAEADYFVAIGTSGHVYPAAGFVHEAKLQGAHTLELNLQPSQVGSEFDEKEYGPASEVVPKFVQNLLRK-------
>tr|A0A0G9N3N6|A0A0G9N3N6_9ENTR NAD-dependent deacetylase OS=Serratia sp. TEL GN=ABA78_17805 PE=3 SV=1
------------------------------------ELKKPFVVVLTGAGISAESGIRTFRAADGLWEEHRVEDVATPEGFQRDPALVQAFYNERRHQLQ
TEDIAPNAAHRALADLEEWL-DNFLLVTQNIDNLHERAGSKRVLHMHGELLKVRCTQSGQVFEWPGDLSVDHCCQFPA---PLRPHVVWFGEMPLGMDDI
YQALSKADFFVAIGTSGHVYPAAGFVHEARLGGAYAMELNLEPSQVESQFDEKHYGLASEVVPRFVHKFLVG-------
>tr|A0A085GAX0|A0A085GAX0_9ENTR SIR2 family NAD-dependent protein deacetylase OS=Ewingella americana ATCC 33852 GN=GEAM_2187 PE=3 SV=1
------------------------------------SLKRPFVVVLTGAGISAESGIRTFRAADGLWEEHKVEDVATPEGYRNDPQLVQAFYNARRQQLQ
NAEIEPNAAHHALATLEDAL-DNFMLVTQNIDNLHERAGNKRVMHMHGELLKVRCTQSGQVFDWPGDLSVDHCCQFPA---PLRPHVVWFGEMPIGMDEI
YQALAKADFFIAIGTSGHVYPAAGFVHEAKMGGAYTIELNLEPSQVESQFDERKYGLASQVVPEFIHAFLTK-------
>tr|R8APZ6|R8APZ6_PLESH NAD-dependent protein deacetylase, SIR2 family OS=Plesiomonas shigelloides 302-73 GN=PLESHI_11005 PE=3 SV=1
------------------------------------HQHIGKVVVLTGAGISAESGIRTFRDQNGLWENHRIEDVATPEGYLRDPEQVQHFYNLRRQELL
SEDLEPNPAHVALATLEAAL-DNFLLVTQNIDNLHERAGNRRIIHMHGELLKARCPESGQTIEWRGDLHTDHCCQIPS---PLRPHVVWFGEMPIGMDKI
YTALAQADLFIAIGTSGNVYPAAGFVHEARLAGAHTVELNLEPSLVENEFAEKLYGKASDVVPAFVNQLLAG-------
>tr|A0A0N2SH33|A0A0N2SH33_YERPE NAD-dependent deacetylase OS=Yersinia pestis subsp. microtus bv. Ulegeica GN=RN23_18050 PE=3 SV=1
------------------------------------EMKKPFVVVLTGAGISAESGIRTFRADDGLWEDHRVEDVATPEGYRRDPELVQRFYNERRRQLQ
QPDIAPNAAHFALADLEAVL-DNLVLITQNIDNLHERAGSKRVIHMHGELLKVRCTQSGQVLDWQGDLSADHCCQFPS---PLRPHIVWFGEMPMGMDDI
YQALAEADFFISIGTSGHVYPAAGFVHESHLHGAHTVELNLEPSQVESQFDEKHYGLASKVVPEYIREFLTT-------
>tr|A0A085JD49|A0A085JD49_9ENTR SIR2 family NAD-dependent protein deacetylase OS=Tatumella ptyseos ATCC 33301 GN=cobB PE=3 SV=1
------------------------------------MTRQPKVVILTGAGISAESGIRTFRAEDGLWEEHKVDDVATPEGFQRDPQRVQQFYNQRRQQLA
SAEIAPNAAHYALAELESLL-DNLLLVTQNIDNLHERAGSQRIIHMHGELLKVRCENTDQVIPWPGDISDNTCCQFPS---VLRPHIVWFGEMPLEMDRI
YQALREATLFIAIGTSGHVYPAAGFVHEARLQGAHTVELNLVPSQVTSEFAERHYGSASELVPEFISGLIRS-------
>tr|A0A095TB04|A0A095TB04_9ENTR NAD-dependent deacetylase OS=Tatumella morbirosei GN=HA49_10685 PE=3 SV=1
------------------------------------KNRLPKVVVLTGAGISAESGIRTFRASDGLWEDHRVEDVATPEGFRRAPERVQEFYNQRRRQLH
SEDIAPNKAHLALARLESVL-DNLLLVTQNIDNLHERAGSQRVVHMHGELLKVRCEESGQVIQWTGDIMADTCCQFPS---RLRPHIVWFGEMPLEMERI
YHALSEANIFIAIGTSGHVYPAAGFVHEATLQGAHTVELNLEPSEVNNEFAECHYGPATTLVPEYISELLKH-------
>tr|H2IU56|H2IU56_RAHAC NAD-dependent protein deacetylase, SIR2 family OS=Rahnella aquatilis (strain ATCC 33071 / DSM 4594 / JCM 1683 / NBRC 105701 / N
------------------------------------SLKKPFVVVLTGAGISAESGIRTFRAADGLWEEHRVEDVATPEGYRRDPELVQRFYNERRRQLQ
AEDLKPNAAHYALATLEEAL-DNFLLVTQNIDNLHERAGSSRVIHMHGELLKVRCTQSGQVLDWPGDLTVDHCCQFPA---PLRPHIVWFGEMPFGMDEI
YDALAKADFFVAIGTSGHVYPAAGFVHEARIGGACAVELNLEPSQVESEFDMKHYGLASQVVPEFVHKFLTK-------
>tr|A0A0A1B5K3|A0A0A1B5K3_9ENTR NAD-dependent deacetylase OS=Pantoea sp. PSNIH2 GN=PSNIH2_10125 PE=3 SV=1
------------------------------------ARPQPRVVVLTGAGISAESGIRTFRADDGLWEEHRIEDVATPEGFARDPALVQAFYNARRRQLQ
QPEIQPNAAHLALAELESVL-DNFLLVTQNIDNLHERAGSQRVLHMHGELLKVRCEMSGQVLEWTGDLSADHCCQFPA---RLRPHVVWFGEMPLGMDKI
YQALSEADYFLAIGTSGHVYPAAGFVHEAKLQGVHTVELNLEPSQVGSQFAEKHYGLASEVVPAWVEKFQKG-------
>tr|U2MHB1|U2MHB1_SERFO NAD-dependent protein deacetylase of SIR2 family OS=Serratia fonticola AU-AP2C GN=L581_0293 PE=3 SV=1
------------------------------------ELKKPFVVVLTGAGISAESGIRTFRAADGLWEEHKVEDVATLDGYQRDPALVQEFYNARRRQLQ
QSDIGPNAAHRALADLEEWL-ENFLLVTQNIDNLHERAGSKQVLHMHGELLKVRCTSSGQVVEWLGDLSVDHCCQFPA---PLRPHVVWFGEMPLGMDEI
YAALAKADFFIAIGTSGNVYPAAGFVHEARLGGAYTMELNLEPSLVESQFEEKHYGPASEVVPRFVHKFLMG-------
>tr|A0A088S7Y6|A0A088S7Y6_9TRYP NAD-dependent deacetylase, putative OS=Leishmania panamensis GN=LPMP_201820 PE=3 SV=1
------------------------------------MKTCRCITVLTGAGISAESGIPTFRDGDGLWCNHRVEDVASPDAFLANPALVQHFYNERRRNLL
LSSVRPNKAHMALARLENEL-TKVVVVTQNVDDLHERAGSTHVLHMHGELLKVRCTVTGKVFVWTKDIVRAPDCGLLG---TLRPHIVWFGEMPLYMDKI
ESVLSETDIFVSIGTSGDVYPAAGFVQRAQFYGSTTLELNLQEGSNNSFFQESIYGKASVIVPAWVDRVLKA-------
>tr|E9BQY9|E9BQY9_LEIDB NAD dependent deacetylase, putative OS=Leishmania donovani (strain BPK282A1) GN=LDBPK_341900 PE=3 SV=1
------------------------------------MKACRCITILTGAGISAESGISTFRDSDGLWCNHNVEDVASPDAFIRNPALVQLFYNERRRNLL
LSSVKPNKAHIALAKLEEELSGKVVIVTQNVDNLHERAG-KNVLHMHGELLKVRCAATGNVFEWQKDIGDVPDCGLLG---TLRPHIVWFGEMPLCMDEI
ESILSKTDLFVAIGTSGNVYPAAGFVKRAQFYGATTLELNLQEGSNSTLFQESIYGKASDIVPAWVDRVLKE-------
>tr|A0A0N0VFW4|A0A0N0VFW4_9TRYP Putative NAD dependent deacetylasemidazole (Cobb) protein OS=Leptomonas pyrrhocoris GN=ABB37_03368 PE=3 SV=1
------------------------------------MRPYRCITILTGAGISAESGIPTFRDSNGLWCSHRVEDVACPDAFLTNPALVQRFYNERRSNLL
ADSVQPNKAHKALATLEKELKTKVVVVTQNIDNLHERAG-ENVLHMHGELLKVRCTKTGAVFPWLKDIREVPDCNALY---TLRPHIVWFGEMPLFMDDI
DAALAETDLFVSIGTSGNVYPAAGFVQRAEFYGAQTLELNLQEGSNNTLFQKSRYGKAGEIVPAWVRTVLEE-------
>tr|C9ZMP3|C9ZMP3_TRYB9 NAD dependent deacetylase, putative OS=Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) GN=TbgDal_IV2480 PE=3 SV=1
------------------------------------RRPNRMIAILTGAGISAESGISTFRDQNGLWENHRVEDVCTPAAFLKQPTVVQRFYNERRRALL
SPEVKPNASHQALARLQREYK-QVVIITQNIDDLHERAG-RQVLHMHGELLKVRCTATGRVFESRDDVHGEECCGVVE---TLRPHIVWFNEMPLYMDVI
DEVVQNAGLFVAVGTSGNVYPAAGLVMIAKAHGAETLELNLEPSGNCRDFDRSVYGPASVIVPAWADEVLHG-------
>tr|S9UMF8|S9UMF8_9TRYP NAD-dependent deacetylase OS=Strigomonas culicis GN=STCU_00836 PE=3 SV=1
------------------------------------MNKLRYITILTGAGISAESGIPTFRDANGLWHNHRVEEVASYDAFRRHPELVQRFYNERRRGVL
QDGIRPNAAHAALARLQRAFA--VTLVTQNVDDLHERAG-TGVLHMHGELLKARCDRTGAVYEWTRDIRDEQCCGTLG---TLRPHIVWFGEMPFYMDDI
SASLAETDLFVAIGTSGVVYPAAGFVQEAQQCGARTLELNLEKGENVSSFHRSIYGKATETVPAWVASVLDG-------
>tr|A0A0N1PFL5|A0A0N1PFL5_LEPSE NAD dependent deacetylase putative transcriptional regulator Sir2 family protein NaMN 5 6-dimethylbenzimidazole (Cobb) protein 
------------------------------------YTAYRCITVLTGAGISAESGIPTFRDSDGLWCSHRIEDVASPDAFLTNPELVQRFYNERRRNLL
LDSVKPNKAHLALAELEKALKTKVVVVTQNIDNLHERAG-SNVVHMHGELLKVRCSKTGAVFPWLKDVREVPDCMELY---TLRPHIVWFGEMPLFMEEI
EAVLAESDLFVSIGTSGNVYPAAGFVQRAEFYGAQTVELNLESCSNSSLFQKSYFGKAGEIVPKWIKEVLEE-------
>tr|D4ZLZ6|D4ZLZ6_SHEVD NAD-dependent deacetylase OS=Shewanella violacea (strain JCM 10179 / CIP 106290 / LMG 19151 / DSS12) GN=npdA PE=3 SV=1
------------------------------------TKMYRQIVILTGAGISAESGIKTFRDQDGLWEAHKIQDVATPEGYARDPELVEGFYNTRWSQLH
SGDVEANAGHDALARLEREF-GDFLLVTQNIDDLHERAG-RRLLHMHGELSKGRCPRSGQTFLLKDPFGPETCCIPAQ---RLRPDVVWFGEIPIGLDRI
QDALDTCDLFIAIGTSGTVYPAAGFVDIANHHGAQTVEVNLVEADRHSQFQFHLQGKASEILPKMVERILSG-------
>tr|A9DIA5|A9DIA5_9GAMM NAD-dependent deacetylase OS=Shewanella benthica KT99 GN=KT99_10583 PE=3 SV=1
------------------------------------MKMYRQIVILTGAGISAESGLRTFRDQDGLWEEHKIEDVATPEGYARDPELVDRFYNTRWSQLH
SGDVEPNAGHDALARLERKF-GELLVVTQNIDDLHERAG-HRLLHMHGELSKGRCPRSRQTFLLKDPFGPETCCIPAQ---RLRPHVVWFGEMPIGLDRI
QHALDTCDLFIAIGTSGTVYPAAGFVDTANHHGAQTVEVNLVEADRHSQFQYHLQGKASEVLPDLVDNILLG-------
>tr|A0A089PPH2|A0A089PPH2_PLUGE NAD-dependent deacetylase OS=Pluralibacter gergoviae GN=LG71_18795 PE=3 SV=1
------------------------------------MMEKPRVVVLTGAGISAESGIQTFRAADGLWEEHRVEDVATPEGFARDPALVQAFYNARRRQLQ
QSAIAPNAAHLALAKLEAEL-DRFLLVTQNIDNLHERAGSRRVIHMHGELLKVRCAWSGQVLEWTGDVNPGHCCQFPQ---PLRPHVVWFGEMPLGMDEI
YSALAAADIFIAIGTSGHVYPAAGFVHEARLQGAHTVELNLEPSQVGSEFEEKHYGMASEVVVTFVDELLKD-------
>tr|A0A0A0CWV8|A0A0A0CWV8_PHOLU NAD-dependent deacetylase OS=Photorhabdus luminescens GN=KS18_00080 PE=3 SV=1
------------------------------------NMKKPYIVVLTGAGISAESGIRTFRSSDGLWEEHRVEDVATPEGFQKDPELVQAFYNARRHQLQ
QSEIKPNAAHYALAALEREL-DNFLLITQNIDNLHERAGSYRTVHMHGELLKIRCCQSGQVFEWTGDLTTDHCCQFPS---PLRPHVVWFGEMPLEMEQI
YSALAQADIFIAIGTSGHVYPAAGFVHEAKLAGAHTVELNLEPSQVESLFDEKHYGPASKIVDEYARRLIDS-------
>tr|A0A087L5S9|A0A087L5S9_9ENTR NAD-dependent deacetylase OS=Serratia sp. Ag1 GN=IV04_05300 PE=3 SV=1
------------------------------------ELKKPFVVVLTGAGISAESGIRTFRADDGLWEEHQVEDVATPEGYRRNPALVQAFYNARRQQLQ
QPSIAPNAAHRVLAELEEWL--NFLLVTQNIDNLHERAGSKRVLHMHGELLKVRCTHSGQVFNWPGELNVEHCCQFPA---PLRPHVVWFGEMPLRMTEI
YEALAKADFFVAIGTSGHVYPAAGFVHEARSAGAYTIELNLEPSQVESQFDEKHYGPASEVVPRFVHKLLMG-------
>tr|V6MUI9|V6MUI9_PROHU NAD-dependent deacetylase OS=Proteus hauseri ZMd44 GN=npdA PE=3 SV=1
------------------------------------EMNLPKVVVLTGAGISAESGIKTFRSEDGLWEEHRVEDVATPEGYQRNPQLVQQFYNERRRQLQ
QPSIQPNKAHYALAKLEQRL-DNFLLVTQNIDNLHEKAGSKHILHMHGELLKVRCPQSRQVFEWKGDLETTHCCQFPS---PLRPHIVWFGEMPMGMEEI
YRALAEADIFISIGTSGNVYPAAGFVHEARLTGAHTVELNLEPSLVESQFEEKHYGPASQVVDEYVHKLFEL-------
>tr|J7TXH1|J7TXH1_MORMO NAD-dependent protein deacetylase of SIR2 family OS=Morganella morganii subsp. morganii KT GN=MU9_2708 PE=3 SV=1
------------------------------------DQFKPKIVVLTGAGISAESGIRTFRSEDGLWEEHNIEDVATPEGYARNPRLVQQFYNDRRRQLQ
SPDVQPNPAHLALAELEQVL-DNFLLVTQNIDNLHERAGSQRIIHMHGELLKIRCAMSGQVQSCTGDLSADHCCQFPS---PLRPHIVWFGEMPFGMDEI
YQALNDADIFIAIGTSGHVYPAAGFVHEARLCGAHTVELNLEPSKVQSEFEECHYGPAGQVVPEYVRQLLAQ-------
>tr|V6IXP2|V6IXP2_9BACL NAD-dependent deacetylase OS=Sporolactobacillus laevolacticus DSM 442 GN=P343_08335 PE=4 SV=1
------------------------------------ISHDQSLVILTGAGISVPSGIPPFRGKNGLYQNADVERCLSIRFFRSHPSEFWAFYRSLFDTDL
LLQAKPNPVHFWIRALEN---DV-TVITQNIDGLHINAG-TNVIEVHGAFHRCVCPKCGALYET-------PQCSTCGT--VLKPDIVLFGESVHGLRDV
EMAVSRTDRLLVLGTSLGVAPINVLPEYAKE-GVPTLLVNDHP-LQMEAISNYV--------QADFNNFNAD-------
>tr|A0A0B5AT41|A0A0B5AT41_9BACL NAD-dependent deacetylase OS=Jeotgalibacillus sp. D5 GN=JMA_40220 PE=4 SV=1
------------------------------------NNKQLNIVVLTGAGVSTDSGIPDFRGKEGVWNKEGNEAIITRSYFMGYPKLFWAQYKELFKEKL
TMNHQPNRVHELVKELET---KV-TVLTQNIDSLHQLAG-EHVLEMHGSYQTASCPKCKLAYDV-------PRCTVCNF--ILKPDVVLFGDTIRHWKEA
EAVLESADLCLILGTSLRVKPFNTLPELAKD-GARLVFINNEG-EFDELMDEIHLGHIDEGLERVLQAFKND-------
>tr|A1ZHW7|A1ZHW7_9BACT NAD-dependent deacetylase OS=Microscilla marina ATCC 23134 GN=M23134_05457 PE=4 SV=1
------------------------------------ES-QQKALFLTGAGISAESGIPTFRGSEGYWTNYTPMEIATNYMFRQFPEKVWRWALHYFNNA-
-RHAQPNPGHQALATLEKRL-QRFTLVTQNVDGLHLLAG-PNTYCIHGTLSHVRCDDCGEVHPFPQDL--ELACPECSE--LMRPHVLFFDEYYEKYESA
LEAAFHTDLLVVVGTTGATNLPLLIFETVLK-GKPIIAINLDN-TF----TQTIKGKSGEILPTLATFF----------
>tr|A0A0G3GY28|A0A0G3GY28_9CORY NAD-dependent protein deacetylase, SIR2 family OS=Corynebacterium mustelae GN=CMUST_00455 PE=3 SV=1
--------------------------------------------MFSGAGMSAESGLDTYRNDTGLWENVDPKAMASISAWHRDPDPMWAWYLWRAHLA-
-SKAEPNAGHMALARWAKLV-PEFHVTTQNIDNLHERAG--SVSHLHGSLFAWRCTDCGTAASD-ISL--RPSCEFCGG--LIRPGVVWFGEALD---VA
QHWMMNADLVVIVGTSGVVQPAASLPYVAHQ-GTPIVEISPAK-ELSALCSFSWDSTAAVALPLITQYVDNL-------
>tr|W5YA89|W5YA89_9CORY NAD-dependent deacetylase OS=Corynebacterium vitaeruminis DSM 20294 GN=B843_10280 PE=3 SV=1
------------------------------------ARGARNIEVFTGAGMSADSGLETYRDPTGVWSKVDPQAMASIDAWVQDPEPMWAWYRWRAGQA-
-MKARPNAGHEAIAYWEGSH--TVHVTTQNIDDLHERAG--EVTHLHGSLFDFRCSICSKPWRDDGDY--RPACSLCGN--PVRPGVVWFGEALE---VA
ERRMQQADLVVIVGTSGIVYPAASLPVLAHQ-GVPILEITPKE-DLSRIATYSWRATAAEGLPALVRRLGV--------
>tr|A0A0F6WQ10|A0A0F6WQ10_9CORY NAD-dependent deacetylase OS=[Brevibacterium] flavum GN=YH66_03520 PE=3 SV=1
------------------------------------AREARNIEVFTGAGMSADSGLETYRDDTGLWSNVDPQAMASIDAWRKDPEPMWAWYRWRAGVA-
-ARAEPNAGHQAISYWEGSD--HVHITTQNIDNLHERAG--DVTHLHGSLFEYRCSDCATPWEDDKNY--RPQCEKCGG--LIRPGVVWFGENLE---IA
EQRIAEADLMIIVGTSGIVHPAAALPQLAQQ-GVPIVEISPTR-ELSRIADFTWMSTAAQALPALMRGLSA--------
>tr|M1UXP4|M1UXP4_9CORY NAD-dependent deacetylase OS=Corynebacterium callunae DSM 20147 GN=H924_03015 PE=3 SV=1
------------------------------------AREARNIEVFTGAGMSADSGLETYRDDTGVWTKVDPQAMASIDAWLKDPEPIWAWYRWRAGVA-
-ARAEPNAGHRAIAYWQGSH--YVHVTTQNIDDLHERGG--DVTHLHGSLFSYYCTDCQQPWEDDRNY--RPLCQNCGG--FIRPGVVWFGEQLT---LA
EQRIAEADLMVIVGTSGIVQPAASLPEMAYQ-GIPIVEISPAP-ELTRWATLSWTATAAQALPALMREISA--------
>tr|A0A0B4DCE6|A0A0B4DCE6_9FLAO Iron dicitrate transport regulator FecR OS=Chryseobacterium taiwanense GN=RM51_13970 PE=4 SV=1
------------------------------------KEKKGYITFLTGAGISAESGIPTYRSIDGIWIYHKPEEFGTYKYFSKNQEEVWQYNLFWKKLI-
-EEAQPNSGHFAITEMEKLL-ERFKLITQNIDGLHQRSG-QKVYEIHGSKQKVRCSKEEPIN-VPDNI--DLKCKKCGN--WLRPHTLWFDESYEHFDTA
YDIADNTDILFVIGTSGSTALPVNIVETVKI-AKWIVLINPES-TY---FDYILQESSSVALPQLKNMIEEV-------
>tr|A0A0J7I601|A0A0J7I601_9FLAO Iron dicitrate transport regulator FecR OS=Chryseobacterium sp. BLS98 GN=ACM40_13865 PE=4 SV=1
------------------------------------KEKRNLFTFLTGAGISSESGLPTYRGSDGIWIYHKPEEFGTFRYFSQNQEEVWQYNLFWKKLI-
-EQATPNQGHFTISKIEQLL-KKFQLITQNVDGLHQKAG-KNIFEIHGNKQTVRCVSGNVMP-IPLEI--DLHCQNCGD--WLRPNTLWFDESYEFLNSA
LKSAKNTGILFVIGTSGATTLPQMLTETVLQ-GGYVIEINTEE-SY---FFERFKKKASDALMNIKEIIEEY-------
>tr|A0A0N0IUR5|A0A0N0IUR5_9FLAO Iron dicitrate transport regulator FecR OS=Chryseobacterium indologenes GN=AOB46_17640 PE=4 SV=1
------------------------------------KERRNLFTFLTGAGISSESGIPTYRGSDGIWVFHKPEEFGTMRYFRQNPEEVLQYSLFRKKMF-
-DNVEPNESHFELAAIENTL-DRFHLITQNIDNLHRRAG-ERIYEIHGNNREIKCSNGKIVN-LPEEI--DLTCPECGH--WMRPNILWFDEYYEKRFSA
LKKAKNSAILFIVGTSGATNLPIAIAETALR-GAFIVDINTED-NF----TKLIREKSTDTLKAIREILESI-------
>tr|A0A0Q4EGP9|A0A0Q4EGP9_9FLAO Iron dicitrate transport regulator FecR OS=Chryseobacterium sp. Leaf201 GN=ASE55_10465 PE=4 SV=1
------------------------------------KEKRNLFTFLTGAGISSESGLPTYRGSDGIWIYHKPEEFGTYAYFSRNQEEVWQYNLFWKKLI-
-DAAHPGQGHFALAEIEKSL-DKFQLITQNVDGLHTKAG-RNIFEIHGNKQTVRCASEGTMP-MPSGL--DLHCPDCGD--WLRPNTLWFDESYEFLDSA
LKAAKNTGILFIIGTSGATNLPQIIAETVLQ-GGYLVEINTEE-SY---FFERFKGKAGDTLAKIKEMTEK--------
>tr|A0A0G3A2T2|A0A0G3A2T2_9DELT NAD-dependent protein deacetylase OS=Archangium gephyra GN=AA314_07681 PE=4 SV=1
------------------------------------GPLGEAVLVITGAGVSLASGIPTFRGTPDAVWANDVTEKGTRAFFKRAPDESWLWYLRRFERA-
-RGAKPNAAHLALAEWERWQ-RAFLLVTQNVDTLHEQAG-RALVKVHGSLDQARCTRRNCANGPPRGT--RPRCPLCQS--KLRPHVLWFDELYHQFERV
LHHARNSRLIVFVGTSFSVGVTAAVSALALK-RIPVFSIDPAG-QPAS-HIHVLAERAEELLPRLVASLPS--------
>tr|A0A095VQL4|A0A095VQL4_9GAMM NAD-dependent protein deacetylase of SIR2 family OS=Pseudohaliea rubra DSM 19751 GN=HRUBRA_01741 PE=4 SV=1
-------------------------------------GRARAVLFVTGAGVSLASGIDTFRGPPGAVWKNDIMEKATLGHFRRDPADAWAWYLARFERV-
-TGAEPNPAHHALVALEDAL-ASSLLVTQNIDGLHHRAG-RALVEIHGKARKVRCASPRCPEGA-FGT--PPRCPHCGD-GLLRPHVLWFDEHYHGFERV
LAYLPTADLVLFVGTSFSVGITDWIVEDSRA-GRGCWSIDPSG-APA--GVRSISGHAEELLPALAQGPE---------
>tr|A0A085WJ82|A0A085WJ82_9DELT NAD-dependent protein deacetylase of SIR2 family protein OS=Hyalangium minutum GN=DB31_8228 PE=4 SV=1
------------------------------------GPAGEAVLVVTGAGVSLASGIPTFRGTPGAVWANDVTQKGTRAYYRQSPHQSWLWYLKRFESL-
-KGAQPNDAHRALAQWQQRQ-REFLLVTQNIDTLHEQAG-RDFVKVHGSSDLARCTQLTCTHGPPYGT--RPRCPVCQS--KLRPHVLWFDEYYHQFDRV
IRQARKSRLVVFIGTSFSVGITAIVTEEARI-GAHVFSIDPAG-SPSH-DIQVVAEGAEVALPRLVASL----------
>tr|A0A0F7DZC2|A0A0F7DZC2_MYXFU NAD-dependent deacetylase OS=Myxococcus fulvus 124B02 GN=MFUL124B02_02520 PE=4 SV=1
------------------------------------GPALVNVLVITGAGISLASGIPTFRGTPDAVWSNEVMEKGTRAFFQRAPHESWKMYLQRFELA-
-RAAKPNAAHRALVAWEAWQ-RGFAVVTQNVDSLHEDAG-RQLVKVHGSLRLARCSAQGCELGAPRGT--PPRCPRCDS--RLRPHVLWFDENYHEIERT
LILARLSRVIVFVGTSFSVGVTELVYRRGRK-DARMFSIDPSN-SLDR-GIEPVTARAEEALPELVRALQS--------
>tr|L7UKR4|L7UKR4_MYXSD NAD-dependent deacetylase OS=Myxococcus stipitatus (strain DSM 14675 / JCM 12634 / Mx s8) GN=MYSTI_05758 PE=4 SV=1
------------------------------------GAPAESVLVVTGAGISLASGIPTFRGTPGAVWANEVMEKGTRAFFKRAPDESWQIYLRRFELA-
-RGAQPNPAHLALVEWEAWQ-RGFAIVTQNVDSLHERAG-RALVKVHGSLDKARCTARGCKLGPPRGT--PPHCPACGS--RLRPHILWFDENYHEIERV
FALARQARLVVFIGTSFSVGATEHIRAIAGK-GARMFSIDPVN-SPAK-DIETVTARAEELLPELMHVLSSK-------
>tr|A1ZPG8|A1ZPG8_9BACT NAD-dependent deacetylase OS=Microscilla marina ATCC 23134 GN=M23134_03775 PE=4 SV=1
------------------------------------LAQDKLITFLTGAGISAESGVPTYRGTDGIWVNYKPEEFATLRFFKENPAEVWKFVLYRKVSF-
-RDLQPNAGHLALASTEVLL-NNFRLITQNIDRLHIKAG-AKVLEIHGNMETVRCSEEMDVYPFPLDI--QLKCPDCGS--LMRPNVLMFDEYYEKQESA
IEAALNTGVLFVVGTSGATNLPHHIASTATY-GSSLVDINIAD-AF----TDMARGTSGDILPQIKQLIQAL-------
>tr|A0A0N1DS33|A0A0N1DS33_9FLAO Iron dicitrate transport regulator FecR OS=Chryseobacterium sp. ERMR1:04 GN=AMQ68_14715 PE=4 SV=1
------------------------------------KEKRNLFTFLTGAGISSDSGIPTYRGTDGIWVFHKPEEFGTFNYFKKHPEEVLQYALFRKKMF-
-EDVEPNQSHFELAEIENIL-DRFHLLTQNIDNLHRRAG-QRIYEVHGNNREIKCSNGEIVN-LPEEI--DLTCQRCGH--WMRPNILWFDEYYEKKFSS
LKVAKNSGVLFIVGTSGATNLPISIAETALK-GATIVDINTED-NF----TELIREKSTEVLKVIKEIIKNI-------
>tr|A0A0M0TR75|A0A0M0TR75_9FLAO Iron dicitrate transport regulator FecR OS=Flavobacterium sp. VMW GN=AKO67_02460 PE=4 SV=1
------------------------------------KKNRNLFTFLTGAGISAESGIPTYRGVDGIWIFHKPEEFGTFKYFKENPEEVWQYSLFRKRMF-
-ENAQTNQSHHEIVAIENLL-DRFHLITQNIDNLHRRAG-ERIYEIHGKAREIKCSNGEIEN-LPAEI--DLKCKECGS--WMRPNILWFDEYYEKKFSS
LKIAKNSGILFIVGTSGATNLPMAIAETTLK-GGTIVDINTED-LF----TQLIRETSTEALKTIREILQNI-------
>tr|A9DQY7|A9DQY7_9FLAO Silent information regulator protein Sir2 OS=Kordia algicida OT-1 GN=KAOT1_16168 PE=4 SV=1
------------------------------------KEKRNNITFLTGAGLSAASGIPTYRSTDGIWVYHKPEEFGTFSYFSKNQEEVWQFNLFRKGMF-
-QKAQPNDSHKLLAKIEKLI-EEFSIITQNIDGLHQRGG-NKVFEIHGNMRTVRCSLEKAVYLYPKDI--ILECPKCGA--VMRPNILWFDEYYEKVDST
MRIAKNTGILIVIGTSGATTLPLELVKQTLK-GGYVLDVNLED-NI----TKLIRTTSDAFLSEFHNILKEL-------
>tr|J1AIL1|J1AIL1_9FLAO Silent information regulator protein Sir2 OS=Flavobacterium sp. F52 GN=FF52_08824 PE=4 SV=1
------------------------------------KNKRNLFTFLTGAGLSSESGIPTYRGVDGIWVFHKPEEFGTFKYFKEHPEEVWQYSLFRKKMF-
-QNAKPNESHYELVEIENIL-DRFHLITQNIDNLHRQSG-ERIFEIHGNNREIKCSNGEIVN-LPEEI--ELKCQSCGS--WMRPNILWFDEYYEKKFSS
LKIAKNSGILFILGTSGATNLPIAIAETTLK-GGTIVDINIED-QF----TALIRKTSTEALKMIKEMIKNI-------
>tr|A0A0C1ZRT3|A0A0C1ZRT3_9DELT NAD-dependent protein deacetylase of SIR2 family protein OS=Enhygromyxa salina GN=DB30_07624 PE=4 SV=1
------------------------------------R--PERVVVVTGAGISAESGIPTFRGPEGYWTEYHPEDMATQVAFSNMPREVWRWYLYRKAVC-
-NQAAPNVAHLALAKLEQAL-DRFMLVTQNVDGLHLRAG-ARTIQVHGSTDLMRAIEGDTPIPIPASM--ALTTP-DGR--RTRPHILWFDECYERAESA
LTAAKSCDLLVVVGTSGAAAIPYHVAAVALR-GVGIIDINPEP-PF----SEHAQGTGSQWVPELVARLT---------
>tr|I5B3Q4|I5B3Q4_9DELT NAD-dependent protein deacetylase, SIR2 family OS=Desulfobacter postgatei 2ac9 GN=DespoDRAFT_02242 PE=4 SV=1
------------------------------------DN-NKRITVLTGAGISAESGIPTFRGPEGYWTEYRPEEMATHSMFTQNPWEVWAWYLYRHTVC-
-KNAKPNSGHHAIARMEELF-DRFCLITQNVDGLHLRAG-ERTFQIHGNINYTRCAGEPRLFEFPEGI--ELTCPRCGS--LARPHILWFDECYEKAESA
MGWATSTDLLLVVGTAGATNLPMQIGMMVARPEAVIVDINLSD-PF----RQFADGPGGKFLPELLSLWEP--------
>tr|A0A0F6YLA1|A0A0F6YLA1_9DELT NAD-dependent protein deacetylase of SIR2 family OS=Sandaracinus amylolyticus GN=DB32_006350 PE=4 SV=1
------------------------------------SR-EGPMLFLTGAGISAESGIPTFRGPEGYWTNYRAEELATYEAFTRMPEEVWAWYLYRRSVC-
-RAASANAAHLALVELERAL-DRFLLITQNVDGLHLRAG-ARTFQIHGNIDYLRCEDEEELHPRIREI--ELQCCGRGR--WSRPHVLWFDESYERFESS
MDAVRRASLVVVIGTSGATTLPSHIVNVAAH-RVPMLVVNQDE-PF----TQIARGTATQYVPAITRALIER-------
>tr|D0LVG3|D0LVG3_HALO1 Silent information regulator protein Sir2 OS=Haliangium ochraceum (strain DSM 14365 / JCM 11303 / SMP-2) GN=Hoch_5036 PE=4 SV=1
------------------------------------LR-EGPCLVLTGAGISAESGIPTFRGKDGYWTVYHPQELATNAAFERLPDEVWQWYLYRRSVC-
-RRAQPNPAHDALVTLEQHL-DAFLLITQNVDGLHPRAG-ARTYSVHGDIDLMRCAAGAELLPVPDQA--QLRCPRCGG--RTRPHVLWFDEYYERFHSS
RDAATRAALLLIVGTSASTNLPWQVVTLAQ-HGATIIDINLES-PF----EPAARQPATAVLPPLVAALCA--------
>tr|A7H7B6|A7H7B6_ANADF Silent information regulator protein Sir2 OS=Anaeromyxobacter sp. (strain Fw109-5) GN=Anae109_0397 PE=4 SV=1
------------------------------------RA-QGRVVALTGAGVSAESGIPTFRGREGFWVNYMPQEMATHEMFARAPEEVWRWYLHRFGVC-
-RDARPNAGHAALVALERAL-ERFTLVTQNIDGLHRRAG-ERVLCIHGDAAYVRCADGTGLLDLPLFP--DLACPSCGG--WLRPHVLWFDEYYERMESA
LRAAAEAELLLVVGTSGATNLPMQIGRLAFE-QAALVDVNPEV-PF----AELARGSACERLPAIVAALGA--------
>tr|S7TFB1|S7TFB1_DESML NAD-dependent deacetylase OS=Desulfococcus multivorans DSM 2059 GN=dsmv_0607 PE=4 SV=1
------------------------------------TS-QQRITVLTGAGISAESGIPTFRGPEGYWTAYRPQEMATQRMFLKAPLAVWNWYLYRRSVC-
-ARAEPNPGHRAVAGMERLF-DRFRLVTQNVDNLHLRAG-ERTFEIHGNIFLMRCAEAAALTPVPAAF--ELRCPRCGG--LLRPHVLWFDEVYERLTTT
LAAARETDLLIVAGTSGTTNLPNKVAWEVSRYKAVIVDVNTDR-PF----AALATGTCGQILPEILALFQAA-------
>tr|E8REN1|E8REN1_DESPD Silent information regulator protein Sir2 OS=Desulfobulbus propionicus (strain ATCC 33891 / DSM 2032 / 1pr3) GN=Despr_1959 PE=4
------------------------------------GG-TGKITILTGAGISAESGIPTFRGPEGYWTVYHPQEMATFHMFCQMPDEVWKWYLYRMGVC-
-GAAQPNPGHLALVDMERHF-DRFTLITQNVDGLHLRAG-ARTYQIHGNVFYMRCSLEEAVHPIPPAV--DLRCPLCGA--RSRPHILLFDESYEHFYSS
LKAAQQTELLIVVGTAGATNLPNQVAREVYQ-DGVIIDINIET-PF----AQLAQEPSASALPALFKVMTAA-------
>tr|C0QHD0|C0QHD0_DESAH NpdA OS=Desulfobacterium autotrophicum (strain ATCC 43914 / DSM 3382 / HRM2) GN=npdA PE=4 SV=1
------------------------------------DG-NGRLTVLSGAGISAESGIPTFRGPEGYWTEYRPEEMATHAMFSRDPWEVWAWYLYRRTVC-
-ASAAPNHGHRAIVEMEALL-DRFRLVTQNVDGLHLNAG-SRTFQIHGNLNFMRCAQGNTLFPFPDQV--ELRCPRCRG--LARPHVLWFDEYYEQAETA
FQWAITTDLLVVVGTAGATTLPMHIGHMIFKPRAILVDINITD-PF----RTLADGPAGDHLNKMVSTWKNH-------
>tr|Q2IGT6|Q2IGT6_ANADE Silent information regulator protein Sir2 OS=Anaeromyxobacter dehalogenans (strain 2CP-C) GN=Adeh_4029 PE=4 SV=1
------------------------------------RGARGNVVALTGAGISAESGIPTFRGA-GYWVNYIPQEMATREMFEAAPEEVWRWYLYRFGVC-
-RDARPNAGHEALVRLEAAL-ERFTLVTQNIDGLHRRAG--RVFCIHGDAAYVRCAACGVGLLDLPAM--ELSCPACGG--WLRPHVLWFDEYYA---MD
SAVREAADLLLVVGTSGATNLPMQIGRIAFH-GAALVDVNPEE-PFAELAGFFARGSACDRLPGIVAALGAG-------
>tr|A1ZHW6|A1ZHW6_9BACT NAD-dependent deacetylase OS=Microscilla marina ATCC 23134 GN=M23134_05456 PE=4 SV=1
------------------------------------ANDQAKMVVLTGAGISAESGIPTFRGKEGYWKNYQPQEIGTMKMFKQNPQEVWKWYLFRHTVC-
-NNSQPNPGHYAVAEMEKIL-KRFTLVTQNVDGLHFRAG-KNTLLIHGDLTHVRCSKDTELLPFPEGI--ELRCPSCGA--LTRPHVLWFDEYYEKYETA
LHKNREADLLIVVGTSGATNLPNKMYYNALN-NKQIVVVNLDS-IF----SRTLLGKSGEILPEILAAIKDT-------
>tr|A0A0M1J990|A0A0M1J990_9GAMM Uncharacterized protein OS=Achromatium sp. WMS3 GN=TI05_14650 PE=4 SV=1
------------------------------------KS-NGKIVFLAGAGISAESGIPTFRGDQGYWTNYHPEDMATFNMFNLKPIEVWKWHIYLHKIC-
-NHAAPNSGHYALVELENIL-DRFSLITQNVDGLHKRAG-ERTFSIHGNLEFSRCSHEDELYPFPKID--ELYCPKCKE--LLRPHILWFDERYEKLQSS
IALAKQADILFLIGTSGVTNLPYRVLSNACY-NSYIVEINPAE-NF----TNIVRETSSTILPKFVNAFKQC-------
>tr|A6G0H3|A6G0H3_9DELT Silent information regulator protein Sir2 OS=Plesiocystis pacifica SIR-1 GN=PPSIR1_37039 PE=4 SV=1
------------------------------------PA-KPKVVVTTGAGISAESGIPTFRGPEGYWTEYRPQELATREAFGKLPKEVWRWYLYRKGVC-
-NAAAPNPAHEALVRLEQAL-ERFCLVTQNVDGLHLRAG-ERTIEVHGNTDYMRPIEGRTPVPIPEAM--MLVAD-DGR--RTRPHVLWFDEYYERSDSA
LRAAGECDLIVVVGTSGAAAIPYHMSAAALE-DAAIIDINPGQ-PF----SDHAHGAGTRWVPALVEGLLAR-------
>tr|A0A0C5XBF5|A0A0C5XBF5_NOCSI NAD-dependent protein deacetylase of SIR2 family OS=Nocardioides simplex GN=KR76_04875 PE=4 SV=1
------------------------------------C-AGGPLVVLTGAGLSTDSGIPDYRGP----A--PARMPMTYQEFVSGPQRYWARSHLGWSRM-
-RRASPNPGHTAVATLG-----ADLVITQNVDGLHEAAG-PALVALHGRIADVICL-CRRTSPRTALQRLGPPCDACGA-GPLKPDVVFFGENVP---RC
YAAVEAGGSLLVAGSSLTVMSGLRFVRRAAQ-EVPVVIVNRGP-RGDDLASYRVEAGVSEWLAALAAVRGPG-------
>tr|A0A0Q8VL95|A0A0Q8VL95_9ACTN NAD-dependent deacetylase OS=Nocardioides sp. Root79 GN=ASE19_07095 PE=4 SV=1
------------------------------------C-ATGPLVVLTGAGLSTDSGIPDYRGP----A--PARMPMTYQEFVSGPQRYWARSHLGWSRM-
-RRADPNAGHRAVAVLG-----ADLVITQNVDGLHEAAG-PHTVALHGRISDVVCL-CRRTTARAALQRLGPACEDCGG--ALKPDVVFFGENVP---RC
YAAVDAGGSLLVAGSSLTVMSGLRFVRRAAH-GTPVVIVNRGT-RGDELATHKVDAGTSEWLTALAGLRAS--------
>tr|A0A0Q8U4J0|A0A0Q8U4J0_9ACTN NAD-dependent deacetylase OS=Nocardioides sp. Root224 GN=ASE24_23070 PE=4 SV=1
------------------------------------L-RDRPLVVLTGAGLSTDSGIPDYRGPEGQSA--PVRMPMTYQEFVSGPQRYWARSHLGWGRM-
-RRAEPNAGHLALARLA-----PGLLITQNVDGLHEQVG-PHLVALHGRISDVVCL-CRTTSARAALQQLDPACD-CGG--VLKPDVVFFGENVA---RC
YDAVDDDGALLVAGSSLTVMSGLRFVRRAAK-GTPVVIVNRGE-RGDPLATYRVDAGCSEFLSELVG------------
>tr|A1SES1|A1SES1_NOCSJ Silent information regulator protein Sir2 OS=Nocardioides sp. (strain BAA-499 / JS614) GN=Noca_0781 PE=4 SV=1
------------------------------------L-AARPLVVLTGAGLSTDSGIPDYRGP----S--PARTPMTYQEFVSGPQRYWARSHLGWGRM-
-RLADPNAGHRALARIA-----PELLITQNVDGLHERAG-PRLVALHGRIADVVCL-CRAASARAALQRLDPGCERCGG--ILKPDVVFFGENVS---RC
YAAVDAGGVLLVAGSSLTVMSGFRFVRRAAG-GVPVVIVNRGA-RGDAHAAYAIDAGCSEFLEDLAARRG---------
>tr|A0A0Q9QLU0|A0A0Q9QLU0_9ACTN NAD-dependent deacetylase OS=Nocardioides sp. Soil777 GN=ASG88_08255 PE=4 SV=1
------------------------------------L-ADRPLVALTGAGLSTDSGIPDYRGP----A--PVRMPMTYQEFVSGPQRYWARSHLGWARM-
-GHAEPNAGHRAMARLDP-----GLLITQNVDGLHEAAG-RQVVALHGRVSEVVCL-CGAITPRAALQRLGPGCDGCGG--LLKPHVVFFGENVE---RC
YAAVEADGVLLVAGSSLTVMSGLRFVKRAAR-GTPVVIVNRGT-RGDDHATYTLSVGCSEFLTDLVERRG---------
>tr|A0A0Q8HJN3|A0A0Q8HJN3_9ACTN NAD-dependent deacetylase OS=Nocardioides sp. Root682 GN=ASD84_15880 PE=4 SV=1
------------------------------------C-ARGPLVVLTGAGLSTDSGIPDYRGP----A--PVRTPMTYQEFVATPQRYWARSHLGWARM-
-GHAAPNAGHHAVAALG-----ADLVITQNVDGLHEAAG-PNLVALHGRVADVICL-CRSTTARTALQRLGPPCEKCGG--LLKPDVVFFGENVE---RC
YTAVEANGTLLVAGSSLTVMSGLRFVRRAAQ-EIPVVIVNRGP-RGDALATHKVEAGTTDWLPELAQSRLTK-------
>tr|A0A0Q8QBV4|A0A0Q8QBV4_9ACTN NAD-dependent deacetylase OS=Nocardioides sp. Root190 GN=ASE01_01155 PE=4 SV=1
------------------------------------C-ATGPLVVLTGAGLSTDSGIPDYRGP----A--PVRMPMTFQEFVSGPQRYWARSHLGWSRM-
-RRADPNAGHLAVAALG-----AGLVITQNVDGLHEAVR-PHLLALHGRIADVVCL-CRRTTSRAALQRLDPSCSDCAG--PLKPDVVFFGESVP---RC
YAAVEAGGTLLVAGSSLTVMSGLRFVRRAAK-GTPVVIVNRGI-RGDDLASYKVEAGTSEWLTALRDARHRA-------
>tr|A0A0Q8W6T1|A0A0Q8W6T1_9ACTN NAD-dependent deacetylase OS=Aeromicrobium sp. Root236 GN=ASE12_11265 PE=4 SV=1
------------------------------------L-GDRRWLVLTGAGVSTDSGIPDYRGP----S--PVRTPMTYQDFVRTPQRYWARAHVGWSRM-
-RGAQPNATHHALADLERQ--RLTGLITQNVDGLHERAG-RDLIDLHGRIDRVICL-CRELTPRADLHRLDAECRTCGG--DLKPDVVFFGENVD---RS
YALVGEAEALVVLGSSLQVMSGLRFVRAAHK-GIPIAIINRGT-RGDDLATVKLEAGCAETLAALTGTAAPA-------
>tr|A0A0Q7K3E7|A0A0Q7K3E7_9ACTN NAD-dependent deacetylase OS=Aeromicrobium sp. Root472D3 GN=ASD10_02240 PE=4 SV=1
------------------------------------L-GDRTWLVLTGAGVSTDSGIPDYRGP----S--TPRTPITYQEFVRTVQRYWARSHVGWTRM-
-WHADPNATHHALVALQDA--RLTGLITQNVDGLHEQAG-RDVIDLHGRIDRVVCL-CHEITTRAALHRLDAPCRTCGG--DLKPDVVFFGENVE---RS
YALVAEAEALVVLGSSLHVMSGLRFVKAAHQ-GIPIVIVNRGT-RGDPLATHKVDAGVAETLATSLRFV----------
>tr|A4AJL9|A4AJL9_9ACTN Regulatory protein, Sir2 family protein OS=marine actinobacterium PHSC20C1 GN=A20C1_02671 PE=4 SV=1
------------------------------------L-SGKLISVLTGAGISTDSGIPDYRGE----A--AVRNPMTFQQFQSAPQRYWAGSHLGWKRF-
-AASAPNDGHAALAELERR--LSNGIITQNVDGLHLRAG-TRVVDVHGSVDRARCL-CGQYFARQPLARIRPECTVCGG--MLKPDVVFFGEFVR---LG
ASLVDQSGALIVAGSSLVVNSGIRLVERALR-QIPLVIINRGI-KADRRADVKIDGGASAALCELLERLTTS-------
>tr|S7XI15|S7XI15_9MICO NAD-dependent protein deacetylase of SIR2 family OS=Leifsonia rubra CMS 76R GN=ADILRU_2181 PE=4 SV=1
------------------------------------L-DGKLISVLTGAGISTDSGIPDYRGQ----A--SVRNPMTFQQFQSSEQRYWAGSHLGWKRF-
-AASAPNGGHSALAEFEGR--LSNGIITQNVDGLHLRAG-KRVVDVHGSIDRARCL-CGQYFARTPLAKISPECTVCGG--MLKPDVVFFGEFVR---LA
SSLVDQSEALIVAGSSLVVNSGIRLVDRALR-NMPLIIINRGE-KADRRADLKLDGGASVILEGLLDRLPR--------
>tr|A0A0F6VID1|A0A0F6VID1_9NOCA NAD-dependent protein deacetylase OS=Rhodococcus aetherivorans GN=cobB PE=3 SV=1
------------------------------------L-DGRRLCVLTGAGISTDSGIPDYRSP----A--PPRNPMTYQQFVGDPRRYWARNHVGWRHM-
-DSARPNAGHRALAALERR--TVLGVLTQNVDLLHTKAG-RRVIDLHGCYAQVRCL-CDLRISRFTLARLSVDCE-CGG--MLKPDIVYFGESVE---RA
FALVDEADALLVVGSSLTVMSGLRFVRHAAK-RMPVAVVNRGV-RGDPLATVKVDAGCSEVLTALVTAAPAA-------
>tr|G7CIW7|G7CIW7_MYCTH NAD-dependent protein deacetylase OS=Mycobacterium thermoresistibile ATCC 19527 GN=cobB PE=3 SV=1
------------------------------------L-RGRRLAVLTGAGISTDSGIPDYRGP----S--PPSNPMTIQQFTSDPQRYWARNHIGWRHM-
-DQTLPNAGHRALAALEAA--VVTGLITQNVDRLHTKAG-RTVIELHGSYDRVICL-CRHTMSRAALALLSIDCP-CAG--MLKPDIVYFGENVQ---KA
LCMVDQADALLVAGSSLTVFSGFRFVRHAAS-GLPIAIINRGP-RGDELATVKVDAGCSEMLALLSCELGVL-------
>tr|I0RGT6|I0RGT6_MYCPH NAD-dependent protein deacetylase OS=Mycobacterium phlei RIVM601174 GN=cobB PE=3 SV=1
------------------------------------L-RGRRLAVLTGAGISTDSGIPDYRGP----S--PPSNPMTIQQFKSDPQRYWARNHLGWRHM-
-DATAPNAGHRALAALEAA--LVSGLITQNVDLLHTKAG-VNVVNLHGTYAQVICL-CGHTMTRAALHLLSVDCP-CGG--MLKPDIVYFGDSVE---QA
YSMVDEADALLVAGSSLTVYSGYRFVRHAAA-GMPIAIINRGP-RGDELATVKVDAGCSPMLALLESELGAV-------
>tr|A0A0M2Z983|A0A0M2Z983_9MYCO NAD-dependent protein deacetylase OS=Mycobacterium elephantis GN=cobB PE=3 SV=1
------------------------------------L-RGRRVAVLTGAGISTDSGIPDYRGP----S--PPSNPMTIRQFTSDPQRYWARNHLGWRHM-
-DTTAPNAGHRALARLERA--VVCGLITQNVDLLHTKAG-RAVVNLHGSYAEVVCL-CGHRMSRAALALLSVDCG-CGG--MLKPDIVYFGENVE---EA
YSVVDAADALLVAGSSLTVYSGYRFVRHAAA-GIPVAIINRGP-RGDELATVKVDSGCSEMLALLVCEFGAH-------
>tr|H0JNK8|H0JNK8_9NOCA NAD-dependent protein deacetylase OS=Rhodococcus pyridinivorans AK37 GN=cobB PE=3 SV=1
------------------------------------L-HGRRIAVLTGAGLSTDSGIPDYRGP----S--PPRNPMTYQQFVGDAQRYWARNHVGWKHM-
-DAARPNPGHRALAALERA--SVVGVITQNVDLLHTKAG-RQVIDLHGTYAQVRCL-CEHRISRFTLHRLDVDCE-CDG--MLKPDIVYFGETVP---LA
FSVVDGADALLVAGSSLTVQSGLRFVRRAVQ-NIPVVVINRGP-RGDALATLKLEAGTSETLAFLADAVTAP-------
>tr|A0A0B0DEI8|A0A0B0DEI8_9MICC NAD-dependent deacetylase OS=Kocuria marina GN=AS25_05050 PE=4 SV=1
------------------------------------L-RGKRIAVLTGAGVSTPSGIPDYRGP----A--KPRSPMTYQEFMGSVRHYWARNQYGWHFV-
-ARAQPSAAHEALARLEAA--LVDGIITQNIDRLHQKAG-VAVVDLHGTYAWVLCT-CSSRFPREQVSYLGWDCPVCQG--VLKPDVVFFGENAH---LA
RRLVARSEALLVAGSSLTVNSGRRFVRQADR-GIPVVIVNHGV-GGDSMATVKVDAPVGEFLADLGEHLTA--------
>tr|A0A060JCP3|A0A060JCP3_9MICO NAD-dependent protein deacetylase, SIR2 family OS=Rhodoluna lacicola GN=Rhola_00008130 PE=4 SV=1
------------------------------------L-IGKKVLVLSGAGLSTDSGIPDYRGA----R--VARHPMTYDTFMGSKIRYWARSFIGWNRI-
-AEALPNAGHLAIARAEVN--KVFQIITQNVDQLHQKAG-RQVIDLHGRLDRVRCM-CGDNFSRTIMDLLDPVCLKCGG--VLKPDVVFFGESVQ---LA
MKNLDDAEALLVAGTSLSVNSGLRFARRAAR-NKPIVIVNIGA-RADELATAKIEANTSLVLERLFLD-----------
>tr|A0A094QFX2|A0A094QFX2_9ZZZZ NAD+---protein-arginine ADP-ribosyltransferase OS=freshwater metagenome GN=GM51_20360 PE=4 SV=1
------------------------------------L-AGKSILVLTGAGVSTESGIPDYRGE----K--TERHPMTFDVFMGSEARYWARSYVGWSVI-
-AKAKPNGSHYALAQAESL--RISHIITQNVDSLHQQAG-RKVTELHGRLDKVICM-CRVLLDRSKMDLINPACPSCSG--ILKPDVVFFGESVE---ST
MEELARVDALLVAGSSLTVNSGMRFARAASK-GKPIVIVNVGP-KADDIAVAKIEAPTSIALEELLID-----------
>tr|A0A0P0RXZ7|A0A0P0RXZ7_9PSEU NAD-dependent deacetylase OS=Pseudonocardia sp. EC080610-09 GN=AD006_13660 PE=4 SV=1
------------------------------------L-AGRRLVALTGAGLSTDSGIPDYRGP----S--RPRNPMTYSEFVSGERRYWARSHVGWGRM-
-RRADPNPGHVALAALEAA--IVDGLITQNVDGLHGVAG-RGVIDLHGRIDEVVCL-CRRITPRDVLQRLGAPCAACGG--VLKPHVVFFGENVD---RC
YALVGSDGALLVAGSSLQVMSGLRFVRACRR-GVPVVIVNRGI-RGDELADLRVDAGCSETLGALAAQPV---------
>tr|A0A0Q7JMM0|A0A0Q7JMM0_9ACTN NAD-dependent deacetylase OS=Angustibacter sp. Root456 GN=ASD06_04115 PE=4 SV=1
------------------------------------L-AGRRVVALTGAGLSTDSGIPDYRGP----S--VPRSPMTYQEFVSGPQRYWARSHVGWGRM-
-RRAEVNDGHRALAAMEGA--ALTALITQNVDGLHSAAG-REVVDLHGRIADVVCL-CGEMTSRAALHRLGAPCLVCRG--PLKPDVVFFGENVD---RC
YDWVEAADVLLVAGTSLTVQSGLRFVRRAAR-GIPVVLVNRGP-RGDDLVDVRIDAGCSPTLTALADALVSS-------
>tr|A0A0M4Q2N4|A0A0M4Q2N4_9PSEU NAD-dependent protein deacetylase OS=Pseudonocardia sp. HH130629-09 GN=cobB PE=3 SV=1
------------------------------------L-AGRRLVVLTGAGLSTDSGIPDYRGP----S--RPRNPMTYSEFVSGEQRYWARSHVGWARM-
-RRADPNPGHRALAAMGAA--VVDGLVTQNVDGLHTVAG-RDVVDLHGRIDEVVCL-CRQITARDALARLGAPCASCGG--VLKPHVVFFGENVD---RC
YAMVATDGALLVAGSSLTVMSGLRFVRAAHR-EVPVVIVNRGA-RGDELADLRVDAGCSEALTALAAQPV---------
>tr|F4CZK5|F4CZK5_PSEUX NAD-dependent protein deacetylase OS=Pseudonocardia dioxanivorans (strain ATCC 55486 / DSM 44775 / JCM 13855 / CB1190) GN=cobB 
------------------------------------L-LGRPLVALTGAGLSTDSGIPDYRGP----S--PARAPMTFGEFRSGPRRYWARSHVGWSRM-
-RHAVPNAGHHALAALEDA--VLRSVITQNVDGLHGAAG-RDVVDLHGRIDEVVCL-CRAVTARDVLQRLGADCAACGG--VLKPHVVFFGENVE---RS
YGLVEGGGALLVAGSSLTVMSGLRFVKRARA-DVPVVIVNRGA-RGDPLATLRVDAGCSETLVALAAA-----------
>tr|A0A0Q5Q1Q5|A0A0Q5Q1Q5_9MICO NAD-dependent deacetylase OS=Microbacterium sp. Leaf351 GN=ASG00_03010 PE=4 SV=1
------------------------------------L-AGRRVAVLTGAGVSTDSGIPDYRGQ----A--PVRRPMTFDQFLADDRRYWVGSHLGWKRF-
-AAAEPNAGHEALARLEHS--AVTGVVTQNVDGLHLRAG-SRVVELHGTMRRVICL-CGQVFDRRDLARIGPTCSVCEG--ALKPDVVFFGEYIE---EA
EQIVRGSDALVIAGSSLVVNSGIRFLDRARR-RLPIVIVNRGD-RGDARATVKIDAGTTEVLRAFADALGGP-------
>tr|A0A094P591|A0A094P591_9ACTN NAD-dependent deacetylase OS=actinobacterium acMicro-4 GN=GM43_1560 PE=4 SV=1
------------------------------------L-RGRPAAVLTGAGVSTDSGIPDYRGV----A--PKQHPMSFSDFLQSHQRYWLGSHMGWSRF-
-AAAEPNRGHEAIASAEEA--LFSGVVTQNVDALHHKAG-LRVVDLHGRLDKVRCI-CGQSFSRQSVATIEPSCDMCDG--VLKPEVIFFGEFVG---QA
ASLIARSEALIIAGSSLVVNTGMRLVNLAHR-KIPIVIINRGP-KADRLATVRIEAGTSETLDALVGGLQSG-------
>tr|A0A0I9YJJ4|A0A0I9YJJ4_9MYCO NAD-dependent protein deacetylase OS=Mycobacterium nebraskense GN=cobB PE=3 SV=1
------------------------------------L-AGCRIAVLTGAGLSTDSGIPDYRGP----S--PPSNPMTIRQFTSDPQRYWARNHVGWRHM-
-DDTAPNAGHRALAALERA--VVTGVITQNVDLLHTKAG-ANVVNLHGTYAQVVCL-CGYTLSRAALAQLSLDCP-CGG--MLKPDIVYFGENVG---QA
YSLVDEADALLVAGSSLTVFSGYRFVRHAAA-SRPIAIINRGP-RGDDLATVKVDGGCSELLALLADELSPI-------
>tr|A0A0Q2UF48|A0A0Q2UF48_MYCGO NAD-dependent deacetylase OS=Mycobacterium gordonae GN=AO501_14995 PE=4 SV=1
------------------------------------L-SGRRIAVLTGAGLSTDSGIPDYRGP----S--PPSNPMTIRQFTSDPQRYWARNHLGWRHM-
-DNTQPNAGHRALAALERA--VVNGVITQNVDLLHTKAG-NNVINLHGTYARVACL-CGHRMSRAALAQLSVDCP-CGG--MLKPDIVYFGESVD---QA
YSLVDQAQALLVAGSSLTVFSGYRFVRHAAA-NIPVAIVNRGR-RGDDLAGVTVDGGCSEILTLLAGELVVS-------
>tr|W9ATH0|W9ATH0_9MYCO NAD-dependent protein deacetylase OS=Mycobacterium cosmeticum GN=cobB PE=3 SV=1
------------------------------------L-TGLRLAVLTGAGMSTDSGIPDYRGP----S--PPSNPMTIAQFTSDPQRYWARNHVGWRHM-
-DDTRPNAGHRALARLEEA--VVMGLITQNVDLLHTKAG-RRVVNLHGTYAQVVCL-CGYTMSRAALAELSLDCP-CAG--MLKPDIVYFGESVD---EA
YSLVDAADALLVAGSSLTVFSGYRFVRHAAA-GMPIAIVNRGP-RGDAQATVKVEGGCSELLTLLAGELPTV-------
>tr|A0A0H5RJ49|A0A0H5RJ49_9MYCO NAD-dependent protein deacetylase OS=Mycobacterium neworleansense GN=cobB PE=3 SV=1
------------------------------------L-QGRRVAVLTGAGMSTDSGIPDYRGP----S--PPSNPMTIRQFTSDPQRYWARNHVGWRHM-
-DNTLPNAGHRALAALEAT--VVNGLITQNVDLLHSKAG-RSVVNLHGTYAQVICL-CGATMGRDELALLSVDCP-CAG--MLKPDIVYFGESVA---QA
YSMVDDGEALLVAGSSLTVYSGYRFVRHAAA-EIPVAIINRGP-RGDDLATVKVEAGCSEMLTLLAGELRRT-------
>tr|A0A051TWE9|A0A051TWE9_MYCTX NAD-dependent protein deacetylase OS=Mycobacterium tuberculosis TKK-01-0051 GN=cobB PE=3 SV=1
------------------------------------L-AGRRITVLTGAGISTDSGIPDYRGP----S--PPSNPMTIRQFTGDPQRYWARNHVGWRHM-
-HDTLPNAGHRALAALEEA--VVTGVITQNVDLLHTKAG-RNVINLHGTYAQVICL-CGATMTRAALGRLSLDCE-CGG--MLKPDIVYFGESVD---EA
YRWVERADALLVAGSSLTVFSGYRFVRHAAA-GIPVAIVNRGG-RGDDLATVKVDGGCSELLALLADELAPL-------
>tr|A0A0I9THN0|A0A0I9THN0_9MYCO NAD-dependent protein deacetylase OS=Mycobacterium heraklionense GN=cobB PE=3 SV=1
------------------------------------L-AGRRVAVLTGAGISTDSGIPDYRGP----S--PPSNPMTIAQFTSDPQRYWARNHVGWRHM-
-ADTAPNTGHLALAALEEA--VVTGVITQNVDLLHTKAG-RHVVDLHGSFATVICL-CGQSLSRASLAQLSVDCR-CGG--ILKPDIVYFGESVV---QA
YSMVDDAEALLVAGSSLTVFSGYRFVRHAAA-GVPVAIVNRGP-RSDELAAVKIDGGCSPVLALLASELASE-------
>tr|X8F604|X8F604_MYCUL NAD-dependent protein deacetylase OS=Mycobacterium ulcerans str. Harvey GN=cobB PE=3 SV=1
------------------------------------L-TGHRIAVLTGAGISTDSGIPDYRGP----S--PPSNPMTIRQFTSDPQRYWARNHVGWRHM-
-DDTAPNAGHRALAALERA--VVTGVITQNVDLLHTKAG-KNVVNLHGTYAQVTCL-CGHTISRSTLAELSIDCR-CGG--MLKPDIVYFGESVE---QA
FSLVDQSDALLVAGSSLTVFSGYRFLRHAAA-GIPVAIINRGH-RGDDLADVKVDGGCSELLVLLASELAAA-------
>tr|A0A0D8HVE6|A0A0D8HVE6_9NOCA NAD-dependent protein deacetylase OS=Rhodococcus sp. AD45 GN=cobB_1 PE=3 SV=1
------------------------------------L-SGRRLAILTGAGISTDSGIPDYRGP----S--PPRNPMTFQQFIGDSRHYWARNHIGWRYM-
-DSSRPNQGHRAVATLERS--RAVGVITQNVDLLHTKAG-RNVIDLHGTYAQVRCL-CQRLISRTTLAQLHVDCG-CGG--ILKPDIVYFGESVE---RA
YNLVDEADAVLVAGSSLTVMSGLRFVRYAAK-GKPVAIVNRGL-RGDELAALKLDIGCTEALSALAASESYS-------
>tr|T1VRG9|T1VRG9_RHOER NAD-dependent protein deacetylase OS=Rhodococcus erythropolis CCM2595 GN=cobB PE=3 SV=1
------------------------------------L-AGRRLAVLTGAGISTDSGIPDYRGP----S--PPRNPMTFQQFIGDPRHYWARNHIGWRYM-
-DSSRPNQGHRAVAALERT--RAVGVITQNVDLLHTKAG-RNVIDLHGTYAQVRCL-CQRLISRTTLARLHVDCA-CSG--LLKPDIVYFGESVE---RA
YSLVDQADALLVAGSSLTVMSGLRFVRHAAK-GKPIAIVNRGT-RGDEYADLKLEVGCAEALSALVEYDSYS-------
>tr|A0A0Q9RCG2|A0A0Q9RCG2_9ACTN NAD-dependent deacetylase OS=Nocardioides sp. Soil796 GN=ASH02_15555 PE=4 SV=1
------------------------------------L-AARPLVVLTGAGVSTDSGVPDYRGP----S--VARTPMTYGEFVSGPQRYWARSHVGWGRM-
-HHALPNAGHRALALLEAR--RVDLLVTQNVDGLHEAAG-SNPIALHGRISDVICL-CRTVSSRSALHRLGPDCEACGG--VLKPDVVFFGENVA---RC
YDAVEADGALLVAGSSLTVMSGLRFVKRSAK-GVPVVIVNRGT-RGDDLATYTLHAGTSEFLGALSARSRSE-------
>tr|A0A0Q9RN85|A0A0Q9RN85_9ACTN NAD-dependent deacetylase OS=Nocardioides sp. Soil797 GN=ASG90_11020 PE=4 SV=1
------------------------------------L-DGQPLVVLTGAGLSTDSGIPDYRGP----A--PVRMPMTFGEFISGPQRYWARSHVGWGRM-
-KRAEPNAGHRALAALEAR--QVRLLITQNVDGLHEAAG-SNALALHGRISDVICL-CRTVSSRRSLQRLGPDCIVCDG--VLKPDVVFFGENVE---RA
YAAVEGGGVLLVVGSSLTVMSGLRFVKRAAK-GVAVVIVNRGT-RGDDLATYKLEAGASEFLGDLAGLGQET-------
>tr|A0A0J8UJB7|A0A0J8UJB7_9MYCO NAD-dependent protein deacetylase OS=Mycobacterium heckeshornense GN=cobB PE=3 SV=1
------------------------------------L-AGRRVVALTGAGISTDSGIPDYRGP----S--PPSSPMTIRQFTSDPRRYWARNHVGWRHM-
-DTAVPNAGHRALARLERC--AVSGIITQNVDLLHTKAG-RTVVNLHGSYARVVCL-CDYLTSRAALAQLAPECP-CAG--MLKPDIVYFGENVN---QA
YSLIDSADALLVAGSSLTVFSGYRFVRHAAA-GMPIAIVNRGR-RGDDLAAVKVDGGCSEVLTLLADELGRA-------
>tr|A0A0Q5MT00|A0A0Q5MT00_9MICO NAD-dependent deacetylase OS=Frigoribacterium sp. Leaf172 GN=ASF89_07565 PE=4 SV=1
------------------------------------L-RGRRVAVLTGAGVSTDSGIPDYRGA----A--PPRNPMTFQQFLSSDKRYWAGSHLGWKAF-
-RASEPNRGHRALAELERA--VTNGVVTQNVDNLHVRAG-QRVVDLHGTVDRVVCL-CGQSFARDMVSRLAPVCTVCGG--MLKPDVVFFGEFVE---EA
RSLVVGAEALLIAGSSLVVNSGIRLLDQATR-RLPVVVVNRGV-KGDGRAAVKLNAGTSETLAALAERLIP--------
>tr|U1LE11|U1LE11_9MICO Uncharacterized protein OS=Agrococcus pavilionensis RW1 GN=L332_13615 PE=4 SV=1
------------------------------------L-RGRRIAVVTGAGISTDSGIPDYRGA----A--PPRNPMLFETFLASARRYWAGSHLGWQRF-
-AGVQPNEGHRALARLERA--LTTGIATQNVDDLHERAG-TNVTHVHGQLHTVSCL-CGTTFDRHRIAEIRPACPVCGG--ILKPDVVFFGELVD---AA
RDIVAAGEVVLVAGSSLVVNSGTRLLEVARR-DVPIVIVNRGP-KWDGRAAARVEGGTSESLSAIADALGAP-------
>tr|A0A099J0E8|A0A099J0E8_9MICO NAD-dependent deacetylase OS=Cryobacterium roopkundense GN=GY21_20270 PE=4 SV=1
------------------------------------L-RNKQTVVLTGAGLSTDSGIPDYRGE----A--PVRNPMTFQTFASNEKRYWAGSHLGWRHF-
-RAAQPNLGHDSLVLLEQS--IVSGIITQNVDGLHTRAG-RHVVELHGSMDRVICL-CGQAFGRDSVARLGPACTVCGG--MLKPNVVFFGEFVE---AA
QSLVQGADALIIAGSSLAVNSGIRLLEQARR-KLPIIVINRGA-KGDGRAVLKLDAGTSETLAGLADRLCP--------
>tr|A0A0Q5LS09|A0A0Q5LS09_9MICO NAD-dependent deacetylase OS=Frigoribacterium sp. Leaf164 GN=ASF82_06480 PE=4 SV=1
------------------------------------L-GGRTVAVLTGAGVSTDSGIPDYRGE----A--PVRNPMTFQQFLSGEKRYWAGSHLGWRSF-
-RAATPNEGHRALARLEAA--VTNGVVTQNVDALHERAG-RRVVDLHGTVDRVVCL-CGQSFARDVVARLAPECTVCGG--MLKPDVVFFGEFVE---EA
RSLVVGADALLIAGSSLVVNSGIRLLDQATR-KMPVVVVNRGV-KGDPRATVKIDAGTSETLTALARRLS---------
>tr|A0A0Q4M6H6|A0A0Q4M6H6_9MICO NAD-dependent deacetylase OS=Frigoribacterium sp. Leaf44 GN=ASE87_05460 PE=4 SV=1
------------------------------------L-RGRRVAVLTGAGVSTDSGIPDYRGE----A--PPRNPMTFQQFLSSEKRYWAGSHLGWKSF-
-RAAGPNEGHRALARLEAA--VTNGVITQNVDNLHVRAG-RRVVDLHGTVDRVVCL-CGQAFARDMVARLAPTCTVCGG--LLKPDVVFFGEFVE---EA
RSMVVGAEALLVAGSSLVVNSGIRLLDQATR-KLPVVVLNRGV-KGDSRATVKLDAGTSETLTALAEHLGA--------
>tr|A0A0Q5HSR6|A0A0Q5HSR6_9MICO NAD-dependent deacetylase OS=Leifsonia sp. Leaf325 GN=ASF62_01675 PE=4 SV=1
------------------------------------M-RGRSTLVLTGAGVSTDSGIPDYRGA----A--PVRNPMTFQQYLADDRRYWAGSHLGWRRF-
-AQAGPNAGHRLLAELEAS--VVSGIVTQNVDGLHTRAG-TRVVPLHGSMDSVVCL-CGQFFARSDIARLAPECTVCGG--MLKPDVVFFGEFVE---EA
QAMLTASDVLMVAGSSLVVNSGIRLVEQARR-RTPIIVVNRGI-KGDGRAVVKIDAGTTEVLRSISEQLAA--------
>tr|A0A0Q5CBG5|A0A0Q5CBG5_9MICO NAD-dependent deacetylase OS=Frondihabitans sp. Leaf304 GN=ASF54_01005 PE=4 SV=1
------------------------------------L-RGRRLAVLTGAGVSTDSGIPDYRGE----A--PVRRPMTFQQFKGDTKRYWAGSHLGYRHF-
-AASRPNDGHRALAALEQA--VTNGVVTQNVDGLHLRAG-SRVVDLHGTVDRVVCL-CGQAFARETVARMAPVCTVCSG--VLKPDVVFFGEFVE---EA
RAMVQSADALVIAGSSLVVNSGIRLLETALR-KAPVVIVNRGV-KGDARAVVKLSAGASETLAALAERLIDA-------
>tr|X7Y1R9|X7Y1R9_MYCKA NAD-dependent protein deacetylase OS=Mycobacterium kansasii 824 GN=cobB PE=3 SV=1
------------------------------------L-AGRRVAVLTGAGISTDSGIPDYRGP----S--PPSNPMTIGQFTSNPRRYWARNHVGWRHM-
-DDTAPNPGHRALAALERA--VVTGVITQNVDLLHTKAG-RNVVNLHGTYAQVVCL-CRYTISRAALAQLSLDCP-CAG--ILKPDIVYFGENVD---EA
YSLVDQAEALLVAGSSLAVYSGYRFVRRAAA-AIPIAIVNRGP-RGDGLAAVKIDSGCSETLTMLAAELASQ-------
>tr|D1AAT9|D1AAT9_THECD NAD-dependent protein deacetylase OS=Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081) GN=cobB P
------------------------------------V-ADGDVVVLSGAGLSTESGIPDYRGE----RRRR-AEPMTYQTFVGSARRYWARSHLGWRHI-
-ARAEPNAGHRAVAELQRR--LVTGIITQNVDGLHQAAG-RDVIELHGSLDRVVCL-CGERTPRRLLQRLGVDCRRCGG--VLKPDVIFFGENVA---EC
YALTERAATLLVLGSSLTVMSGHRFVRHAAR-AIPVAIINRGP-RGDDLALVKWDAPLGAALSALVVAC----------
>tr|A8L5B7|A8L5B7_FRASN NAD-dependent protein deacetylase OS=Frankia sp. (strain EAN1pec) GN=cobB PE=3 SV=1
------------------------------------V-AGGGVAVLTGAGMSTDSGIPDYRGP----SLRQ-HTPMTYQQFNRDQRRYWARSHLGWRHV-
-AGARPNTGHRALAELEAA--LLDGVITQNVDGLHRAAG-LRVIDLHGELARVRCR-CGALSARAELDRLGVGCTGCGG-D-LEPDVVFFGATVA---SA
VALVENARGLLVLGSSLAVMSGYRFVLRAGE-GIPVGIVNQGP-RGDARAEFTVDSPLGAVLPRLAAELLGA-------
>tr|W2F1H3|W2F1H3_9ACTN NAD-dependent protein deacetylase OS=Microbispora sp. ATCC PTA-5024 GN=cobB PE=3 SV=1
------------------------------------V-SDGDVVVLSGAGLSTESGIPDYRGE----RARR-ADPMTYQTFVRSERRYWARSHLGWRQI-
-ARAAPNAGHHAVAELQDR--LLAGIITQNVDGLHQAAG-REVIELHGGLDRVVCL-CGERTSRYLLERLDVDCLGCGG--LLKPDVIFFGENVS---AC
YALTERAGTLLVLGSSLTVMSGYRFVRHAAE-AIPVAIVNRGA-RGDAHALVALDAPLGATLTALLSGLGG--------
>tr|F4F1M6|F4F1M6_VERMA NAD-dependent protein deacetylase OS=Verrucosispora maris (strain AB-18-032) GN=cobB PE=3 SV=1
------------------------------------V-AGGEVVVLSGAGLSTESGIPDYRGP----VARR-HTPMTYQMFVGDARRYWARSHLGWRLM-
-AQAAPNDGHRAVARLQHG--LVSGVITQNVDGLHTAAG-RDVVELHGRLDQVICL-CGQRTSRQELDRLGVDCRSCGG--MLKPDVVFFGETVG---DC
FAMVAAARLLLVLGSSLTVLSGRRFVTAAAR-GVPVVIVNQGA-RGDAHALLRVDAPLGQVLPALAQRLLTA-------
>tr|A0A0Q6VGH5|A0A0Q6VGH5_9ACTN NAD-dependent deacetylase OS=Nocardioides sp. Root122 GN=ASC64_02905 PE=4 SV=1
------------------------------------L-TGRPLVVLTGAGLSTDSGIPDYRGP----A--PARAPMTYQEFVATPRHYWARSHVGWQRM-
-GHASPNDGHRALTTLDP-----LLLITQNVDGLHEAAG-RRMVALHGRVADVVCL-CRATSSRAELEVLDPTC-ECGG--PLKPDVVFFGENVD---RC
YAAVEAGGALLVAGSSLTVMSGLRFVKRAAQ-GTPVVIVNRGT-RGDELASYKLEVGCSEFLTELVRRSLDL-------
>tr|A0A0Q5DGJ8|A0A0Q5DGJ8_9ACTN NAD-dependent deacetylase OS=Nocardioides sp. Leaf307 GN=ASF50_18185 PE=4 SV=1
------------------------------------L-ADRDLVVLTGAGLSTDSGIPDYRGP----A--PTRTPMTYQEFVATPRRYWARSHLGWGRM-
-RHADPNTGHRALVEVD-----PDLLITQNVDGLHERAG-PRLVALHGRIADVVCL-CRRTTSRAALHRLSPDCD-CGG--ILKPDVVFFGENVP---RC
YDAVDAGGALLVVGSSLTVMSGFRFVRRAAR-GTPVVVVNRGA-RGDALATYAVEAGCSGFLADLAARRVG--------
>tr|A0A0Q9TDE3|A0A0Q9TDE3_9ACTN NAD-dependent deacetylase OS=Nocardioides sp. Soil805 GN=ASG94_06575 PE=4 SV=1
------------------------------------L-DGRPLVALTGAGLSTDSGIPDYRGP----A--PVRMPMTYQEFVAGPQRYWARSHLGWARM-
-GHAEPNAGHRALARLDP-----ELLITQNVDGLHEAAG-RQLVALHGRVSEVVCL-CRRVTPRAALQRLGPGCAECEG--PLKPHVVFFGENVE---RC
YAAVDAAGALLVAGSSLTVMSGLRFVKRAAR-GTPVVIVNRGT-RGDEHATYRLGTGCSEFLTALAAGRG---------
>tr|R7XSL9|R7XSL9_9ACTN Silent information regulator protein Sir2 OS=Nocardioides sp. CF8 GN=CF8_3829 PE=4 SV=1
------------------------------------L-AERDLVVLTGAGLSTDSGIPDYRGP----A--PTRTPMTFQEFVSGPQRYWARSHLGWARM-
-GAAVPNAGHVALAQIDP-----RLLITQNVDGLHEAAG-DRLVALHGRVADVVCL-CRRTSPRAALQRLDAVCDDCGG--VLKPDVVFFGENVD---RC
YDAVDADGALLVAGSSLAVMSGLRFVKRAAA-GTPVVIVNRGL-RGDDLATHKLEVGTSDFLASLADELAQR-------
>tr|A0A0Q6FW80|A0A0Q6FW80_9ACTN NAD-dependent deacetylase OS=Marmoricola sp. Leaf446 GN=ASG49_03570 PE=4 SV=1
------------------------------------L-GP-RTVVLTGAGLSTDSGIPDYRGP----A--PARRPMTYQEFVATPQRYWARAHVGWSRM-
-GSAEPNAGHRALVRLEAA--RVPLLITQNVDGLHERAG-QQLVALHGRVSKVVCL-CGRTSDRAPLQRLDPGCEACGG--RLKPHVVFFGENVD---RC
YAAVDDADSLLVVGSSLTVMSGLRFVRHAAK-GTPVVLVNRGA-RGDDLATLKLETGCSGWLSDLADAAEQE-------
>tr|A0A0Q9QI91|A0A0Q9QI91_9ACTN NAD-dependent deacetylase OS=Nocardioides sp. Soil774 GN=ASG76_01060 PE=4 SV=1
------------------------------------L-ATRPLVVLTGAGLSTDSGIPDYRGP----A--PARAPMTYQEFVATPRRYWARSHVGWQRM-
-GRAVPNDGHRALAALDP-----ELLITQNVDGLHEAAG-RQVVALHGRVADVVCL-CRATSSRADLQRLDPRC-PCGG--PLKPHVVFFGENVE---RC
YAAVEADGALLVAGSSLTVMSGLRFVKRAAA-GTPIVIVNRGL-RGDALATYKLEVGCSEFLGGLARQSLTL-------
>tr|H8E2X2|H8E2X2_9MICO NAD-dependent deacetylase OS=Microbacterium laevaniformans OR221 GN=OR221_1200 PE=4 SV=1
------------------------------------L-SGRRIAVLTGAGVSTDSGIPDYRGK----A--PTRTPMTAQQFLSSARRYWVGSHLGWRAF-
-AAAQPNGGHLALAELESR--IASGVITQNVDGLHVRAG-RRVVELHGTMRRVLCT-CGQVFDRRDLARVGPECSVCRG--MLKPDVVFFGEYIA---EA
EQLVQTSEALVIAGSSLVVNSGIRLLERARR-KLPVVIVNRGQ-RGDARATVKIDAGTTEVLRALARALPAK-------
>tr|A0A031FZ70|A0A031FZ70_9MICO NAD-dependent deacetylase OS=Microbacterium oleivorans GN=BW34_00165 PE=4 SV=1
------------------------------------L-AGHRVAVLTGAGLSTDSGIPDYRGK----A--PVRTPMTAQEFLADDRRYWVGSHLGWRTF-
-AAASPNQGHRALADLEKA--IATGVITQNVDGLHVRAG-RRVVELHGTMRRVSCL-CGQVFDRRDLARIGPDCSVCGG--MLKPEVVFFGEYIE---EA
EQLLRSSNALLIVGSSLVVNSGIRLLDRARR-RLPVVIVNRGE-RGDKRATVKIDAGASEVLTVLGDALAAV-------
>tr|A0A0Q6E4T2|A0A0Q6E4T2_9MICO NAD-dependent deacetylase OS=Microbacterium sp. Leaf436 GN=ASG45_11860 PE=4 SV=1
------------------------------------L-AGRRIAVLTGAGVSTDSGIPDYRGK----A--PTRTPMTAQQFLSNARRYWVGSHLGWKVF-
-AAAEPNDGHRALADLERA--VANGVVTQNVDGLHVRAG-GRVVELHGTMRRVGCL-CGQVFDRRDLARVGPVCSVCGG--TLKPDVVFFGEYIE---EA
EQLVHTSGALVIAGSSLVVNSGIRLVERARR-RLPVVIVNRGE-RADQRAAVKIDGSTTHVLRALAERLPAL-------
>tr|U2XI76|U2XI76_9MICO NAD-dependent protein deacetylase, SIR2 family OS=Microbacterium sp. TS-1 GN=MTS1_00273 PE=4 SV=1
------------------------------------L-AGRRIAVLTGAGVSTDSGIPDYRGA----A--PVRTPMTAQQFLASARRYWVGSHLGWQAF-
-AAARPNDGHAALADLERS--VVTGVITQNVDGLHLRAG-SRVVELHGTMRRVFCL-CGQVFDRRDLARVGPTCTVCGG--MLKPDVVFFGEFVE---EA
EQLVRTSEALIVAGSSLVVNSGVRLVERARR-KLPVVIVNRGA-RSDPKATVKIDDGTSRVLRVFADALASR-------
>tr|A0A0P0E8B7|A0A0P0E8B7_9MICO NAD-dependent deacetylase OS=Microbacterium sp. No. 7 GN=AOA12_12605 PE=4 SV=1
------------------------------------L-AGCRIAVLTGAGVSTDSGIPDYRGK----A--PTRTPMTWQTFRESERRYWVGSHLGWRAF-
-SAAAPNRGHAALAALEEH--LASGVVTQNVDGLHLQAG-RRVIELHGTMRRVGCT-CGQVFDRRDLARIRPDCSVCGG--MLRPDIVFFGEYVL---EA
EQLVAASGALLVAGSSLAVNSGVRLVERARR-RLPVVIVNRGE-RADRRASVKIDAGTSEVLQALSDGLLAR-------
>tr|A0A0Q8ANC2|A0A0Q8ANC2_9MICO NAD-dependent deacetylase OS=Microbacterium sp. Root166 GN=ASD56_10170 PE=4 SV=1
------------------------------------L-AGRRIAVLTGAGVSTDSGIPDYRGK----A--PVRTPMTVEQFLSSERRYWVGSHLGWRAF-
-AASEPNGGHLALADLEQS--IATGVITQNVDGLHLRAG-RRVVELHGTMRRVFCT-CGQVFDRRDLARVDPVCTVCGG--MLKPDVVFFGEYIE---EA
EQLVHTSEGLVIAGSSLVVNSGIRLLERARR-RLPVVIVNRGL-RADARATVKVEGGTSEVLRALADALPSA-------
>tr|A0A0Q7TWB0|A0A0Q7TWB0_9MICO NAD-dependent deacetylase OS=Microbacterium sp. Root53 GN=ASD19_02055 PE=4 SV=1
------------------------------------L-AGRRVAVLTGAGVSTDSGIPDYRGK----A--PRRTPMTAQTFLSDERRYWVGSHLGWRAF-
-SAAEPNAGHEALAALERD--IVTGVVTQNVDGLHLRAG-HRVVELHGTMRRVFCT-CGQVFDRRDIARLGPACSVCDG--VLKPDVVFFGEFIG---EA
EQLLLASEALLIAGSSLVVNSGIRLVERARR-RLPVVIVNRGE-RADNRATVKIDAGTSAVLSELARALPAA-------
>tr|A0A0M2H3F4|A0A0M2H3F4_9MICO NAD-dependent protein deacetylase OS=Microbacterium ketosireducens GN=cobB_2 PE=4 SV=1
------------------------------------L-SGRRVAVLTGAGVSTDSGIPDYRGQ----A--PVRTPMTVEQFLASERRYWVGSHLGWRAF-
-AAAEPNGGHRALAALENR--LTTGVVTQNVDGLHVRAG-RRVVELHGTMRRVFCT-CGQVFDRRDLARVDPACSVCGG--MLKPDVVFFGEFIE---EA
EQLVQTSQALLIAGSSLVVNSGIRLLERARR-RLPVVIVNRGA-RADARATVKVDAGTSEMLQALAAALPPI-------
>tr|W0Z9R4|W0Z9R4_9MICO NAD-dependent protein deacetylase 1 OS=Microbacterium sp. C448 GN=cobB PE=4 SV=1
------------------------------------L-SGRRVAVLTGAGVSTDSGIPDYRGN----A--PVRSPMTAQQFMADERRYWLGGHLGWHAF-
-SSAQPNAGHEAIARLEAD--FATGVVTQNVDGLHVRAG-GRVVELHGTMRRVFCT-CGQVFDRRDISRIGPDCSVCDG--LLKPDVVFFGEFIE---EA
EQLLKTSQALLIAGSSLVVNSGIRLVERARR-RLPVIIVNRGA-RADNRATLKIDAGTSEVLGALAAGLAAT-------
>tr|A0A0Q8LUG2|A0A0Q8LUG2_9MICO NAD-dependent deacetylase OS=Microbacterium sp. Root180 GN=ASD93_06305 PE=4 SV=1
------------------------------------L-AGRRIAILTGAGVSTDSGIPDYRGR----A--PVRTPMTAEQFLANERRYWVGSHLGWRTF-
-AAAEPNDGHRAIAELEQS--VATGVVTQNVDGLHVRAG-RRVVELHGTMRRVFCT-CGQVFDRRDLARVGPQCTVCGG--MLKPDVVFFGEFIE---EA
EQLVQASDGLVIAGSSLVVNSGIRLLERARR-RLPVVIVNRGV-RADARATVKVDAGTSEVLRALAGALPSA-------
>tr|A0A0M2H6A3|A0A0M2H6A3_9MICO NAD-dependent protein deacetylase OS=Microbacterium trichothecenolyticum GN=cobB_2 PE=4 SV=1
------------------------------------L-SGRRIAVLTGAGVSTDSGIPDYRGA----A--PVRTPMTVEQFLSSDRRYWVGSHLGWRAF-
-ASAEPNPGHRAIADLEAR--LATGVVTQNVDGLHVRAG-RRVVELHGTMRRIFCT-CGQVFDRRDLARVGPECSVCGG--MLKPDVVFFGEFIE---EA
EQLVHTSEALIVAGSSLVVNSGIRLLERARR-RLPVVIVNRGA-RADARATVKIDAGTSEVLRALADGLPSL-------
>tr|A0A0M9VLP1|A0A0M9VLP1_9MICO NAD-dependent deacetylase OS=Microbacterium chocolatum GN=XI38_05820 PE=4 SV=1
------------------------------------L-AGRRIAVLTGAGVSTDSGIPDYRGQ----A--PVRTPMTVEQFLASERRYWVGSHLGWTAF-
-AAAAPNAGHRALAALEER--LLTGVVTQNVDGLHVRAG-RRVVELHGTMRRVFCV-CGQVFDRRDLARVGPVCTVCTG--MLKPDVVFFGEYIE---EA
EQLVLTSQALLIAGSSLVVNSGIRLLERARR-RMPVVIVNRGS-RADARATVKIDGGTSEVLGILAETLPAL-------
>tr|A0A0B2A182|A0A0B2A182_9MICO NAD-dependent deacetylase OS=Microbacterium mangrovi GN=LK09_19600 PE=4 SV=1
------------------------------------L-AGKRIAVLTGAGISTDSGIPDYRGE----A--PRRTPMTVDQFFASDRRYWIGSHLGWKAF-
-AAAEPNAGHRALAELEHA--VVTGIITQNVDGLHLRAG-ARVVELHGTMRRVLCT-CGQVFDRRDIARLGPECTVCGG--LLKPDVVFFGEFIG---GA
EQLVHASDALLVAGSSLVVNSGIRFTERARR-HLPLVIVNRGA-RADAAATVKIDSGTSEVLAALASALAG--------
>tr|X5L6W0|X5L6W0_9MYCO NAD-dependent protein deacetylase OS=Mycobacterium mageritense GN=cobB PE=3 SV=1
------------------------------------L-QGRRVAVLTGAGMSTDSGIPDYRGP----S--PPSNPMTIRQFTADAQRYWARNHVGWRHM-
-DLTMPNAGHRALATLESA--VVTGLITQNVDLLHTKAG-RAVVNLHGTYAQVVCL-CGHTMTRAALAELTLDCP-CGG--MLKPDIVYFGENVE---RA
YSLVDTADALLVAGSSLTVYSGYRFVRHAVA-GMPVAIINRGP-RGDELATVKIDAGCSELLTLLAGELTRT-------
>tr|A0A0Q8ZRQ3|A0A0Q8ZRQ3_9MYCO NAD-dependent deacetylase OS=Mycobacterium sp. Root265 GN=ASE48_12560 PE=4 SV=1
------------------------------------L-TGCRVAVLTGAGMSTDSGIPDYRGP----S--PPSNPMTIGQFRSDPQRYWARNHLGWRHM-
-DDTVPNAGHRALARMESA--VVTGLITQNVDLLHTKAG-THVVNLHGTYAQVVCL-CGRTMSREALAELSLDCP-CGG--MLKPDIVYFGESVE---QA
FSLVDAADALLVAGSSLTVFSGYRFVRHAAA-GMPIAIINRGP-RGDALATVKLEAGCSELLTLLAGELAST-------
>tr|A0A024QWA2|A0A024QWA2_MYCNE NAD-dependent protein deacetylase OS=Mycobacterium neoaurum GN=cobB PE=3 SV=1
------------------------------------L-AGRRLVVLTGAGMSTDSGIPDYRGP----S--PPSNPMTIAQFRSDAQRYWARNHIGWRHM-
-DQTQPNAGHRALAALEAA--VLTGLITQNVDLLHTKAG-RTVVNLHGTYQQVICL-CGFTMSRAALAELSLDCP-CGG--MLKPDIVYFGESVE---QA
FSLVDAADALLVAGSSLTVFSGYRFVRHAAA-QLPIAIINRGP-RGDDLATVKVDGGCSELLALLAGELPLM-------
>tr|A0A0D1L8F1|A0A0D1L8F1_9MYCO NAD-dependent protein deacetylase OS=Mycobacterium llatzerense GN=cobB PE=3 SV=1
------------------------------------L-ADRRIAVLTGAGISTDSGIPDYRGP----S--PPSNPMTIQQFLSGPQRYWARNHIGWLHM-
-AARRPNAGHRAVAALERA--LVTGVITQNVDLLHTKAG-QTVVNLHGTYAQVICL-CGHTMTRAELAELTLDCP-CGG--ILKPDIVYFGDSVD---QA
YALVDEADALLVAGSSLTVYSGYRFVRHAAA-GKAVAIINRGT-RGDDLATVKIDSGCSEILALLASELPAQ-------
>tr|A1TC19|A1TC19_MYCVP NAD-dependent protein deacetylase OS=Mycobacterium vanbaalenii (strain DSM 7251 / PYR-1) GN=cobB PE=3 SV=1
------------------------------------L-QGRRVAVLTGAGMSTDSGIPDYRGP----S--PPSNPMTIRQFTSDPQRYWARNHLGWRHM-
-DQTQPNAGHRALAALEHA--VVSGVITQNVDLLHSKAG-KVVIDLHGTYARVICL-CGHTMARATLALLSVDCP-CGG--MLKPDIVYFGESVE---QA
FSLVDGADALLVAGSSLTVYSGYRFVRHAAA-GKPVAIINRGR-RGDDLADVKIDNGCSPMLALLADELPGL-------
>tr|G8RJG9|G8RJG9_MYCRN NAD-dependent protein deacetylase OS=Mycobacterium rhodesiae (strain NBB3) GN=cobB PE=3 SV=1
------------------------------------L-SGRRIAVLTGAGMSTDSGIPDYRGP----S--PPSNPMTIRQFTSDRQRYWARNHVGWRHM-
-HETMPNAGHRALAALERA--VVSGLITQNVDLLHTKAG-TDVVNLHGTYAQAVCL-CAFTMSRAALALLAVDCP-CTG--MLKPDIVYFGENVE---QA
YSLVDDADALLVAGSSLTVYSGFRFVRHAAA-QIPIAIINRGR-RGDDYAAVKVDNGCSEMLALLADELPAL-------
>tr|A1UJ04|A1UJ04_MYCSK NAD-dependent protein deacetylase OS=Mycobacterium sp. (strain KMS) GN=cobB PE=3 SV=1
------------------------------------L-AGRRVAVLTGAGMSTDSGIPDYRGP----S--PPSNPMTIRQFTSDPQRYWARNHVGWRHM-
-AATLPNAGHRALAAMERT--VVLGVVTQNVDLLHTKAG-RNVVDLHGTYARVICL-CGYTMSRADLAMLRVDCP-CGG--MLKPDIVYFGESVP---QA
FAVVDDADVLLVAGSSLTVFSGYRFVRHAAA-GMPVAIINRGP-RGDDLATVKLDNGCSPMLALLADELPAF-------
>tr|E6TDT9|E6TDT9_MYCSR NAD-dependent protein deacetylase OS=Mycobacterium gilvum (strain DSM 45189 / LMG 24558 / Spyr1) GN=cobB PE=3 SV=1
------------------------------------L-AGRRVAVLTGAGMSTDSGIPDYRGP----S--PPSNPMTIRQFTSDPRRYWARNHLGWRHM-
-DDTQPNAGHRALAALERA--VVTGVITQNVDLLHTKAG-ERVIDLHGTYARVICL-CHRTMSRASLALLSVDCP-CGG--MLKPDIVYFGENVE---EA
YSLVDGAEALLVAGSSLTVYSGFRFVRHASA-GIPVAIINRGH-RGDDLATVKIDNGCSPMLALLADELPAA-------
>tr|L8F7A0|L8F7A0_MYCSM NAD-dependent protein deacetylase OS=Mycobacterium smegmatis MKD8 GN=cobB2 PE=3 SV=1
------------------------------------L-QGRRIVALTGAGMSTDSGIPDYRGP----S--PPSNPMTIQQFTSDPQRYWARNHVGWRHM-
-DQTQPNAGHRALAAMEAS--VVAGVITQNVDLLHTKAG-REVINLHGTYAQVVCLNCGHTMSRAALAMLSVDCP-CGG--MLKPDIVYFGDSVT---QA
YSMVDGADALLVAGSSLTVFSGYRFVRHAAA-GIPVGIVNRGP-RGDDLAAVKVHSGCSEMLTLLAGELTRT-------
>tr|F5YY95|F5YY95_MYCSD NAD-dependent protein deacetylase OS=Mycobacterium sinense (strain JDM601) GN=cobB PE=3 SV=1
------------------------------------L-AGRRTAVLTGAGISTDSGIPDYRGP----S--PPSNPMTIAQFTGDPQRYWARNHLGWRHL-
-AGAAPNAGHTALATLEAS--VVTGVITQNVDLLHTRAG-RRVIDLHGSYAAVVCL-CGTMMSRSSLAQLSLDCH-CGG--ILKPDIVYFGESVD---QA
YAVVDEAEALLVAGSSLTVFSGYRFVRHAAA-GIPVAIVNRGP-RGDGLADVKFDGGCSAALTVLAAELGAV-------
>tr|K5B853|K5B853_9MYCO NAD-dependent protein deacetylase OS=Mycobacterium hassiacum DSM 44199 GN=cobB PE=3 SV=1
------------------------------------L-RGRRVAVLTGAGISTDSGIPDYRGP----S--PPSNPMTIQQFVSDPQRYWARNHLGWRHM-
-DATLPNAGHRALAELERL--VVCGIITQNVDLLHTKAG-RVVINLHGSYAQVVCL-CGHRMTRAALHMLSVDCP-CGG--MLKPDIVYFGDSVE---QA
FSLVDQADALLVAGSSLAVFSGYRFVRRAAA-EMPIAIINRGP-RGDDLATIKVDAGCSETLTELVDAMRAA-------
>tr|C5BXB6|C5BXB6_BEUC1 NAD-dependent protein deacetylase OS=Beutenbergia cavernae (strain ATCC BAA-8 / DSM 12333 / NBRC 16432) GN=cobB PE=3 SV=1
------------------------------------L-AGRRLAVLTGAGISTDSGIPDYRGP----S--PPRNPMTYQQFVGDPRHYWARNHVGWHHM-
-TATEPNAGHRALAALEQR--AVAGVVTQNVDLLHEAAG-RRVVDLHGHYNEVVCL-CGTTVTRTELDRLDAACE-CGG--VLKPNIVYFGENVE---RA
FEIVDDGDALLVAGSSLAVMSGLRFVRHAAR-GKPVVVVNRGV-RGDALATVLLHAGTTETLVELDRRLPDV-------
>tr|A0A0B4E1R4|A0A0B4E1R4_KOCRH NAD-dependent deacetylase OS=Kocuria rhizophila GN=RK09_00135 PE=4 SV=1
------------------------------------L-VGRRIAVLTGAGVSTSSGIPDYRGP----A--KPRNPMTYQEFIADVRHYWARNQFGWHFV-
-ARAEPSAAHTALATLETA--AVDGIITQNIDRLHQKAG-LAVVDLHGTYAWVVCT-CRSRFPREEVSYLGWDCPVCQG--VLKPDVVFFGENAL---LA
RRMVTHADALLVAGSSLTVNSGRRYVRQAAR-GKPVVIVNHGV-GADELATLKVDARVGEFLTDLASLLVP--------
>tr|I0HF71|I0HF71_ACTM4 Putative Sir2-family regulator protein OS=Actinoplanes missouriensis (strain ATCC 14538 / DSM 43046 / CBS 188.64 / JCM 3121 / N
------------------------------------I-AEGGVAVLTGAGLSTDSGIPDYRGP----SARR-GTPMTYQTFTSDPRRYWARSHLGWRTI-
-GGARPNEGHAAVARWQES--LLAGLITQNVDGLHQAAG-RDVVELHGNLSRIVCL-CRELTSRVELERLGVPCRSCGG--VLKPDVVYFGETVD---RS
FELVETARTLLVLGSSLTVMSGRRFVLRAVR-GIRVAIVNRGV-RGEPYADMVIDAPLGVVLPNLATDTDNH-------
>tr|R4LRX2|R4LRX2_9ACTN Silent information regulator protein sir2 OS=Actinoplanes sp. N902-109 GN=L083_6226 PE=4 SV=1
------------------------------------V-ADGGVVVLSGAGLSTESGIPDYRGP----AARR-STPMTYQTFTRDPRRYWARSHLGWRTI-
-GDARANAGHRAVARLQEL--RIDGIITQNVDGLHQDGG-HGVVELHGNLARVACL-CGEITGRAALERLGVNCAGCGG--MLKPDVVYFGETVS---RS
FELVAGARTLLVLGSSLTVMSGRRFVLRAAK-GIRIAIVNQGV-RGEPYAQLIVDGPLGSILPRLAQDVDDA-------
>tr|U5W9J6|U5W9J6_9ACTN Silent information regulator protein Sir2 OS=Actinoplanes friuliensis DSM 7358 GN=AFR_31925 PE=4 SV=1
------------------------------------T-GDGGVVVLSGAGLSTESGIPDYRGP----AARRSATPMTYQAFTRDPRRYWARSHLGWRTI-
-GDARPNDGHRAVARLQEL--RVDGIITQNVDGLHQAGG-HGVVELHGNLSRITCL-CGELTAREEHSRLGVDCLACGG--MLKPDVVYFGETVA---RS
FELVAGARTLLVLGSSLTVMSGRRFVLRAAK-GIRVAIVNQGV-RGEPYAGLIVDAALGEVLPELVRRIEGA-------
>tr|A0A0A6UMC7|A0A0A6UMC7_ACTUT NAD-dependent protein deacetylase OS=Actinoplanes utahensis GN=cobB PE=3 SV=1
------------------------------------V-AEGGVAVLSGAGLSTDSGIPDYRGP----SARR-TQPMTYQTFTGDPRRYWARSHLGWRTI-
-GAARPNDGHRAVARLQEQ--LLAGVVTQNVDGLHQAAG-RDVIELHGNLARVVCL-CGELSGRAELERLGVDCLSCGG--LLKPDVVYFGETVD---RA
FGLVASARTLLVLGSSLTVMSGRRFVLRAAR-GIRVAIVNRGV-RGEPYADLVVDAPLGIVLPHLAKPIPVP-------
>tr|G8S7H4|G8S7H4_ACTS5 Silent information regulator protein Sir2 OS=Actinoplanes sp. (strain ATCC 31044 / CBS 674.73 / SE50/110) GN=ACPL_6672 PE=4 SV=
------------------------------------L-GDGGVVVLSGAGLSTDSGIPDYRGP----SARR-NTPMTYQTFTGDPRRYWARSHLGWHTI-
-GLARPNDGHRAVARWQER--LLHGVITQNVDGLHQAAG-RDVVELHGNLARITCL-CGALTPRTELARLGVDCLACGG--LLKPDVVYFGETVE---RA
FELVAGARTLLVLGSSLTVMSGRRFVLRAVK-GVRVAIVNRGV-RGEPYADLVIDAPLGVVLPNLAAETETY-------
>tr|D5UHX5|D5UHX5_CELFN NAD-dependent protein deacetylase OS=Cellulomonas flavigena (strain ATCC 482 / DSM 20109 / NCIB 8073 / NRS 134) GN=cobB PE=3 SV
------------------------------------L-AGHRLTVLTGAGISTDSGIPDYRGP----S--PPRSPMTFQQFVGDERHYWARNHVGWRHV-
-HRTLPNAGHRALAALEGR--VVHGVITQNVDLLHEAAG-RHVIDLHGRYDRVVCL-CHRVVPRAVLARLGQACWQCGG--VLKPDIVYFGENVE---RA
YAMVDAGDALLVAGSSLTVHSGRRFVRHAAL-GKPVVVVNRGA-RGDRYATRTLDAGTSETLTALADLLAPL-------
>tr|F4H2H4|F4H2H4_CELFA NAD-dependent protein deacetylase OS=Cellulomonas fimi (strain ATCC 484 / DSM 20113 / JCM 1341 / NBRC 15513 / NCIMB 8980 / NCTC
------------------------------------L-QGRRLTVLTGAGVSTDSGIPDYRGP----S--PPRNPMTFQQFTGDERHYWARNHVGWRHV-
-HRTQPNAGHRALAQMERE--TLLGVITQNVDLLHEQAG-RNVIDLHGRYDRVVCL-CRTVVSRSELARLHADCA-CGG--MLKPDIVYFGETVE---RA
YAMVDAADALLVAGSSLTVQSGLRFVRHAAQ-GTPVAIVNRGV-RGDRYATVTLHAGTSETLSALADSL----------
>tr|A0A0C2JMV5|A0A0C2JMV5_9ACTN NAD-dependent protein deacetylase OS=Streptomonospora alba GN=cobB PE=3 SV=1
------------------------------------L-GRGPVAVLTGAGISTDSGIPDYRGP----S--PPRKPMTYQQFVGDARHYWARNHVGWRHV-
-HRTRPNDGHRALAGLEEA--VVSGVITQNVDTLHGMAG-RSVIDLHGRYDRVTCL-CASVISRDRLARLGADCA-CGG--ILKPDIVYFGENVQ---ES
YRLVDDAEALLVAGSSLTVLSGRRFVKRAAD-GKPVVIVNRGP-RADALAAVTVDAGCSRALGALAGAYQR--------
>tr|F8A5V8|F8A5V8_CELGA NAD-dependent protein deacetylase OS=Cellulomonas gilvus (strain ATCC 13127 / NRRL B-14078) GN=cobB PE=3 SV=1
------------------------------------L-AGRRLAVLTGAGVSTDSGIPDYRGP----S--PPRTPMTFQQFMGDERHYWARNHVGWRHV-
-GRTLPNAGHRALAELERR--VVGGLITQNVDLLHQAAG-RHVIDLHGRYDRVVCL-CGTVISRAELARLHAACA-CGG--VLKPDIVYFGELVE---RA
YAMVDAADALLVAGSSLTVQSGLRFVRHAAR-GKPVVVVNRGA-RGDRYAAVALDGGTSETLTELAQELPAP-------
>tr|A0A0Q7PFT4|A0A0Q7PFT4_9CELL NAD-dependent deacetylase OS=Cellulomonas sp. Root137 GN=ASD18_04965 PE=4 SV=1
------------------------------------L-AGHRLAVLTGAGVSTDSGIPDYRGP----S--PPRTPMTFQQFTSDERHYWARNHVGWRHV-
-HRTMPNAGHRALAALEHR--VVTGLITQNVDLLHEAAG-RHVIDLHGRYDRVRCL-CGTVISRAELARLGAACS-CGG--MLKPDIVYFGENVE---RA
YALVDGADALLVAGSSLSVQSGLRFVRHAAQ-GKPVVVVNRGA-RGDKYAAVTLDAGTSETLTDLAETLPTP-------
>tr|A0A0J6DKD2|A0A0J6DKD2_9CELL NAD-dependent protein deacetylase OS=Cellulomonas sp. A375-1 GN=cobB PE=3 SV=1
------------------------------------L-AGHRLTVLTGAGVSTDSGIPDYRGP----S--PPRTPMTFQQFVGDERHYWARNHVGWRHV-
-NRTLPNKGHRALVALEQR--VVLGIITQNVDLLHEAAG-RHVIDLHGRYDRVVCL-CGTVIGRRELARLHADCA-CGG--MLKPDIAYFGETVE---RA
YALVDAGDALLVAGSSLTVQSGLRFVRHAAQ-GKPVVVVNRGA-RGDRYAVVTLDAGTSETLTELAEVLPAP-------
>tr|A0A077LTW1|A0A077LTW1_9MICO NAD-dependent protein deacetylase OS=Tetrasphaera japonica T1-X7 GN=npdA PE=3 SV=1
------------------------------------L-VGCSPLVLTGAGMSTESGIPDYRGP----QR--RVRPMQYAEFVGSSQRYWARSYVGWQRF-
-HRARPNVGHEAVAALQAA--RVGPVITQNVDGLHQRAG-RDVIDLHGSLADVVCL-CGDRSDRRDLDRMAPTCQVCGR-DTLKPDVVFFGESVA---RC
LALTDAARGLLVLGSSLAVMSGYRFVRRAAA-RIPVGIVTHGP-RGDAEATVRLDAPLGRTLAALAAAVGAS-------
>tr|E3BCL4|E3BCL4_9MICO Transcriptional regulator, Sir2 family OS=Dermacoccus sp. Ellin185 GN=HMPREF0321_1544 PE=4 SV=1
------------------------------------V-RAGGLFVLTGAGISTESGIPDYRRP----T--RRTVPMTYQQFLATHQRYWARSAVGWEIF-
-DAAEPNVGHVALARLQGG--LVDHLVTQNVDGLHARAG-RDVTELHGSLEHVVCV-CGTREGRRGFQRLGPACLRCTA-TTVKPDVVMFGESVE---AQ
MRALERCRGVLVLGSSLKVMSGYRFVLAALK-QKPVALVGLGA-RGEERVDLVVREPLGPTLTAVCDALGLD-------
>tr|K1ESU2|K1ESU2_9MICO Silent information regulator protein Sir2 OS=Janibacter hoylei PVAS-1 GN=B277_04115 PE=4 SV=1
------------------------------------L-SVGPALVLTGAGMSTDSGIPDYRGP----TR--RVTPMHYGEFVGSSQRYWARSYVGWRRF-
-HAARPNAAHHLVTRLQDL--AVGPVITQNVDGLHQAAG-RDVVELHGSLVEVVCL-CEAREDRRTLDRMRPRCLVCGD-DTLKPDVVFFGGSVP---HC
YDLVDAAPSLLVLGSSLQVMSGLRFVRHAAK-GIPVLLITRGP-RGDDLVDHRVDGELAPSLRHLVGAVEDL-------
>tr|A0A0Q9KFP7|A0A0Q9KFP7_9MICO NAD-dependent protein deacetylase 1 OS=Janibacter sp. Soil728 GN=ASG73_05370 PE=4 SV=1
------------------------------------L-TAGPALVLTGAGMSTDSGIPDYRGP----TR--RVTPMHYSEFVGSSQRYWARSFVGWRRF-
-HAARPNISHHLVTRLQQL--TVGPLITQNVDGLHQAAG-SDVVELHGNLVEVVCL-CEARVDRPTLDRMRPLCQACGA-DTLKPDVVFFGGAVP---HC
YDLVDTAPSLLVLGSSLQVMSGLRFVRHAAK-GIPVSLITRGP-RGDDLVDHRVDEELGDSLRSLVELLSSA-------
>tr|A0A0Q6LR24|A0A0Q6LR24_9MICO NAD-dependent protein deacetylase 1 OS=Phycicoccus sp. Root101 GN=ASC58_01305 PE=4 SV=1
------------------------------------L-GHGNVLTLTGAGISTESGIPDYRGP----NR--RVTPMQYSEFVRSSQRYWARSYVGWQRF-
-NLARPNAGHEAVTTLQRG--YLGPVITQNVDGLHQQSG-TEVTELHGALARVVCL-CGDRSSRWDLDRMDPLCLVCQH-DTLKPDVVFFGESVP---HC
FRLTEEADVLLVLGSSLKVMSGYRFVRRAAA-GIPVVIITRGS-RGDAEATVQVDAPLGPTLTELVSRLVA--------
>tr|A0A0K1JKN3|A0A0K1JKN3_9MICO Uncharacterized protein OS=Luteipulveratus mongoliensis GN=VV02_17730 PE=4 SV=1
------------------------------------V-AAGGLSVLTGAGLSTESGIPDYRGP----E--RRITPMTATELLASPQRYWARSYVGWRRF-
-EGARPNVGHQVVARLQAR--LLGTVITQNVDGLHQQAG-VDVLELHGSLSHVVCM-CGERYDREVIDRLTATCVVCGS-DKLKPDVVMFGEAVP---KC
FGVVEQSDGLLVLGSSLMVMSGYRFVRRASR-GLPVAVLTRGR-RGEAETTIKIETPLGETLTHLEQALPQ--------
>tr|H0E712|H0E712_9ACTN NAD-dependent protein deacetylase of SIR2 family OS=Patulibacter medicamentivorans GN=PAI11_26140 PE=4 SV=1
------------------------------------L-ATGDVLVLTGAGVSTDSGIPDYRGP----ER--RVTPMQFREFTDSSQRYWARAFVGWQRF-
-SSVVPNAGHEAIARLQGA--HVGSVITQNVDGLHQRAG-RDVVELHGSLADVVCL-CRDRSSRWDLERMSPRCLVCAQ-DTLKPDVVFFGESVA---RC
FDLTDRAAALLVLGSSLKVFSGYRFVRRAAA-GIPVAIVTRGP-RGDGEATLRIDAGLGETLTALGDRLGV--------
>tr|A0A0Q9LWU7|A0A0Q9LWU7_9MICO NAD-dependent protein deacetylase 1 OS=Phycicoccus sp. Soil748 GN=ASG70_07940 PE=4 SV=1
------------------------------------I-ERRRVLTLTGAGISTESGIPDYRGP----KR--RVTPMQYAEFVRSSQRYWARSYVGWQRF-
-NLARPNTGHEAVAALQRA--ALGPVITQNVDGLHQSAG-SDVTELHGALARVVCL-CGDRSSRWDLDRMDPRCLVCGQ-DTLKPDVVFFGESVP---HC
FRLTEEAEVLLVLGSSLKVMSGYRFVRRAAA-GIPVVIITRGA-RGDGEATLQLDAPLGPTLTELVRLLAA--------
>tr|E9V157|E9V157_9ACTN Transcriptional regulator, Sir2 family OS=Nocardioidaceae bacterium Broad-1 GN=NBCG_04796 PE=4 SV=1
------------------------------------L-QDRRLVVLTGAGVSTDSGIPDYRSP----S--PSRQPMTYQQFISGPQRYWARSHLGWRRM-
-GSAVPNAGHRALATID-----PELLITQNVDGLHEQAAPGRIVTLHGRVADVICL-CRTVSPRRDLQRMDPDCEICGG--ILKPDVVFFGENVD---RC
MDAVDAKGVLLVAGSSLAVMSGYRFVRRAAK-GIPVVIVNRGA-RGDGEATYKLEVGTSEFLTALSSRRA---------
>tr|F5XPN6|F5XPN6_MICPN NAD-dependent deacetylase OS=Microlunatus phosphovorus (strain ATCC 700054 / DSM 10555 / JCM 9379 / NBRC 101784 / NCIMB 13414 /
------------------------------------L-RDRTWTALTGAGASTDSGIPDYRGP----S--VRATPMQFSEFIGATQRYWARSYLGWERM-
-GTARPNPAHQALVELESA--LV-GVVTQNVDGLHARAG-RLVVNLHGEIAWVVCL-CGTRVHRGEVQWLHACCAACGG--RLKPDVVFFGESVD---FA
HDLVDAGEVLVVLGSSLTVMSGLRFVRHLAK-GKDVVIVNRGV-RGDPLATLKIDGGCAETLAPLVGALR---------
>tr|D2S8Y6|D2S8Y6_GEOOG NAD-dependent protein deacetylase OS=Geodermatophilus obscurus (strain ATCC 25078 / DSM 43160 / JCM 3152 / G-20) GN=cobB PE=3 S
------------------------------------V-GDGNTVVLSGAGLSTDSGIPDYRGA----S-LRRHTPMTYQTFLRDPHRYWARSFVGWPQI-
-REARPNAGHAAVADLQRA--LVGGVITQNVDGLHQAAG-RDVLELHGGLDRTVCL-CGDVADRGQLHRLGVDCAACGR-GPLKPDVVFFGETVD---TC
FAMVEQAGSLLVLGSSLTVMSGYRFVLRAEK-GIPVGLVNLGP-RGDAKVDVRVDAPLGTVLPDLVRRVAA--------
>tr|A0A098Y726|A0A098Y726_9ACTN NAD-dependent protein deacetylase OS=Modestobacter sp. KNN45-2b GN=cobB PE=3 SV=1
------------------------------------L-TDGGAVVLSGAGLSTDSGIPDYRGA----S-LRRHTPMTYQTFTRDPHRYWARSYVGWRQI-
-ERARPNAGHRAVAALQQA--AVGEVITQNVDGLHQAGG-REVLELHGGLDRTVCL-CGDMASRADLDRLGVDCLACGG-GPLKPDVVFFGETVN---AC
FALVDAARSLLVLGSSLTVMSGYRFVIAAAK-GIPVAIVNSGS-RGDAKATLKVDAPLGVVLPELARRLA---------
>tr|I4ESJ9|I4ESJ9_MODMB NAD-dependent protein deacetylase OS=Modestobacter marinus (strain BC501) GN=cobB PE=3 SV=1
------------------------------------L-ADGGALVLSGAGLSTDSGIPDYRGA----S-LRRHTPMTWQTFTRDPHRYWARSFVGWRQI-
-GEARPNAGHRAVAALQAA--AVGAVITQNVDGLHQAAG-REVVELHGGLDRTVCL-CGDVADRAALDRLGVDCLACGG-GPLKPDVVFFGETVD---HC
FGLVDRARSLLVLGSSLTVMSGYRFVIHAAK-GIPVAIVNSGP-RGDAKADLKVDAPLGAVLPELARRVG---------
>tr|A0A0Q5W496|A0A0Q5W496_9ACTN NAD-dependent deacetylase OS=Modestobacter sp. Leaf380 GN=ASG41_05700 PE=4 SV=1
------------------------------------V-GNGNTVVLSGAGLSTDSGIPDYRGA----ARQRRHTPMTWQTFTRDPHRYWARSFVGWRQI-
-EQARPNAGHRAVAALEHA--LLGGLITQNVDGLHQAGG-TDVLELHGGLDRTVCL-CGDVADRAALDRLEVDCLACGG-GPLKPDVVFFGETVE---RS
YELVTCARSLVVLGSSLTVMSGFRFVLRAAK-GIPVAIVNSGP-RGDDKADVRVDAPLGTVLPALARRLVR--------
>tr|M3E6P1|M3E6P1_9ACTN NAD-dependent protein deacetylase OS=Streptomyces gancidicus BKS 13-15 GN=cobB PE=3 SV=1
------------------------------------L-RAGGVLVLSGAGISTESGIPDYRGE----SLSR-HTPMTFQEFVGGARRYWARSHLGWRTF-
-GRALPNAGHRAVAAFARH--LVSGVITQNVDGLHQAAG-EGVVELHGSLDRVVCL-CGRTSPRRDLARLGVPCAVCGG--VLKPDVVFFGETVQ---LC
RRMVRESTSLLVLGSSLTVMSGLRFVRLAAE-GKPVLIVNRDA-RGDRHALTRVGLPLGAALTTVAERLDVT-------
>tr|A0A0K0Y027|A0A0K0Y027_9GAMM NAD-dependent protein deacetylase OS=Wenzhouxiangella marina GN=WM2015_2885 PE=4 SV=1
------------------------------------VDAHPRLLVLTGAGLSTRSGIPAYRNA----GKWLRRDPILYQDFIAEARRYWARSFFGWSMM-
-QTAQPNSAHRALAAMEGD--RIELLVTQNVDGLHRAAG-EALVELHGALDRVSCL-CGEGITRNALQALGVDCANCGG--RLKPDVVFFGESVE---RI
EAALAACDGLLVVGSSLVVMSGFRIVRGARA-GRPVVAINDGR-RADGLLEFKVGGDCVEVLTALTEA-----------
>tr|D6Y4W1|D6Y4W1_THEBD NAD-dependent protein deacetylase OS=Thermobispora bispora (strain ATCC 19993 / DSM 43833 / CBS 139.67 / JCM 10125 / NBRC 14880
------------------------------------V-ADGEVVVLSGAGLSTESGIPDYRGV----RLRR-SQPMTYQTFIGSARRYWARSHLGWRHM-
-AEARPNAGHHAVAELQRR--LVAGIITQNVDGLHQAAG-RDVIELHGSLSRVRCL-CGERTPREVLDRLGVDCASCGG--VLKPDVVFFGENVD---AC
LELAERAGLLLVLGSSLAVMSGYRLVRHAAD-GIPIAIINQGP-RGDAHALVTIDARLGSALPRLLARLDAA-------
>tr|A0A066Y5Y7|A0A066Y5Y7_9ACTN NAD-dependent protein deacetylase OS=Streptomyces olindensis GN=cobB PE=3 SV=1
------------------------------------L-GTGGVLVLSGAGISTESGIPDYRGE----SLSR-HTPMTYQDFVAGARRYWARSHLGWRTF-
-GRALPNAGHRAVAAFGRH--LLSGVITQNVDGLHQAAG-EDVVELHGALDRVVCL-CGARSPRRELARLGVPCAVCGG--ILKPDVVFFGETVQ---HC
RELVRAASSLLVLGSSLTVMSGLRFVRQAAQ-GKPVLIVNRDP-RGDRHALTRVALPLGTALTAVADRLGIA-------
>tr|A0A0K8PVI8|A0A0K8PVI8_STRAJ NAD-dependent protein deacetylase OS=Streptomyces azureus GN=cobB PE=3 SV=1
------------------------------------L-STGGVLVLSGAGISTESGIPDYRGE----SLSR-HTPMTYQDFTASARRYWARSHLGWRTF-
-GRARPNAGHRAVAAFGQH--MLSGVITQNVDGLHQAAG-EDVVELHGSLARVVCL-CGAFSPRRELARLDVPCTICGG--ILKPDVVFFGEAVR---HC
RELVRESTSLLVLGSSLTVMSGLRFVRLAAQ-GKPVLIVNREP-RGDRHAFTRVSLPLGAALTTVAERLGIA-------
>tr|D7CBH8|D7CBH8_STRBB NAD-dependent protein deacetylase OS=Streptomyces bingchenggensis (strain BCW-1) GN=cobB PE=3 SV=1
------------------------------------L-STGGVLVLSGAGISTESGIPDYRGE----SLSR-HTPMTYQDFIADARRYWARSHLGWRTF-
-GRARPNPGHRAVAAFARN--LLSGLITQNVDGLHQAAG-EGVVELHGSLDRVVCL-CGALGPRRELARLDVPCTVCGG--ILKPDVVFFGEAVR---HC
RKLVREATSLLVLGSSLTVMSGLRFVRQAAQ-GKPVLIVNLDP-RGDRHAVTRVALPLGTALSAVASRLGIP-------
>tr|A0A0M8XCG3|A0A0M8XCG3_9ACTN NAD-dependent protein deacetylase OS=Streptomyces sp. NRRL B-1140 GN=cobB PE=3 SV=1
------------------------------------L-RSGGVLVLSGAGISTESGIPDYRGE----SLSR-HTPMTYQEFTAATRRYWARSHLGWRTF-
-GRARPNAGHRAVAAFGRH--LLTGVVTQNVDGLHQAAG-DDVVELHGALDRVVCL-CGAHSPRRELARLGVPCTACGG--ILKPDVVFFGEAVQ---HC
RELVRAATSLLVLGSSLTVMSGLRFVRQAAQ-GKPVLIVNRDQ-RGDQYALTRVSLPLGAALSSVSLRLGIP-------
>tr|G2GDI7|G2GDI7_9ACTN NAD-dependent protein deacetylase OS=Streptomyces zinciresistens K42 GN=cobB PE=3 SV=1
------------------------------------L-GGGGVLVLSGAGLSTESGIPDYRGE----SLNR-HTPMTYQEFTASARRYWARSQLGRRTF-
-GRARPNAGHRAVAAFGRR--LLTGVITQNVDGLHRAAG-EGAVELHGSLARVVCL-CGTFSARRELARLDVPCARCGG--VLKPDVVFFGENVE---HC
RALVREAASLLVLGSSLTVMSGLRFVRQAAE-GKPVLIINRDP-RGDRHAVTRVALPLGATLTALAERLGVQ-------
>tr|A0A0M8YF85|A0A0M8YF85_9ACTN NAD-dependent protein deacetylase OS=Streptomyces sp. NRRL F-6491 GN=cobB PE=3 SV=1
------------------------------------L-GAGGVLVLSGAGLSTESGIPDYRGE----SLSR-HTPMTYQDFTASPRRYWARSHLGWRTF-
-GRARPNAGHRSVAAFGRH--LLSGVITQNVDGLHQAGG-EGVVELHGSLDRVVCL-CGTFSPRRDLARLDMPCALCGG--VLKPDVVFFGEAVS---HC
RELVREATSLLVLGSSLTVMSGLRFVRQAAQ-GKPVLIVNRDP-RGDRYAVTRVALPLGAALTAVADRLGVP-------
>tr|A0A0N1GT45|A0A0N1GT45_9ACTN NAD-dependent protein deacetylase OS=Actinobacteria bacterium OV320 GN=cobB PE=3 SV=1
------------------------------------L-SAGGVLVLSGAGISTESGIPDYRGE----SLSR-HTPMTYQDFTSDPRRYWARSHLGWRTF-
-GRARPNAGHRAVAAFARR--LLAGLITQNVDGLHQAAG-EDVVELHGSLGRVVCL-CGAFSPRRELARLDVPCAVCGG--ILKPDVVFFGETVP---HC
RTLVREATSLLVLGSSLTVMSGLRFVRQAGQ-GKPVLIVNRDP-RGDRHALARVALPLGTTLTTVAGRLGIL-------
>tr|A0A089YRX0|A0A089YRX0_STRGA NAD-dependent protein deacetylase OS=Streptomyces glaucescens GN=cobB1 PE=3 SV=1
------------------------------------L-GGGGVLVLSGAGISTESGIPDYRGE----SLSR-HTPMTYQEFTADAQRYWARSHLGWRTF-
-GRARPNAGHRAVAAFGRH--LLSGVVTQNVDGLHQAAG-EGVVELHGSLARVVCL-CGAVSPRRELARLDVPCAVCGG--VLKPDVVFFGEAVR---HC
RELVRRARSLLVLGSSLTVMSGLRFVRQAAQ-GTPVLIVNRDP-RGDRHALTRVELSLGPALTAVAGRLGIA-------
>tr|H1QC67|H1QC67_9ACTN NAD-dependent protein deacetylase OS=Streptomyces coelicoflavus ZG0656 GN=cobB PE=3 SV=1
------------------------------------L-RTGGVLVLSGAGISTESGIPDYRGE----SLSR-HTPMTYQDFTGSPRRYWARSHLGWRTF-
-GRARPNAGHRSVAAFARH--LLTGVITQNVDGLHQAAG-EDVVELHGSLDRVVCL-CGVLSARRELARLDLPCTVCGG--ILKPDVVFFGENVG---HC
RELVREASSLLVLGSSLTVMSGLRFVRQAAG-GKPVLIVNRDA-RGDRLAVTRIALPLGPALTRVAEGLGVT-------
>tr|D9XLT4|D9XLT4_9ACTN NAD-dependent protein deacetylase OS=Streptomyces griseoflavus Tu4000 GN=cobB PE=3 SV=1
------------------------------------L-STGGVLVLSGAGISTESGIPDYRGE----SLSR-HTPMTYQDFTGSTRRYWARSHLGWRTF-
-GRARPNSGHRAVAAFGRR--LLTGVITQNVDGLHREAG-EGVVELHGGLDRVVCL-CGDLSARRELARLDVPCTVCGG--ILKPDVVFFGETVQ---HC
RALVRAAESLLVLGSSLTVMSGLRFVRQAAD-GKPVLIVNRDP-RGDRHAVTRVALPLGTALTTVAGRLGVP-------
>tr|A0A0M8UIZ9|A0A0M8UIZ9_9ACTN NAD-dependent protein deacetylase OS=Streptomyces sp. H036 GN=cobB PE=3 SV=1
------------------------------------L-SAGGVLVLSGAGISTESGIPDYRGE----SLRR-HTPMTYQEFTASARRYWARSHLGWRTF-
-GRARPNAGHRAVTAFGRH--LLSGVITQNVDGLHQAAG-EDVVELHGSLDRVVCL-CGASGSRRDLARLDVPCAQCGG--VLKPDVVFFGETVR---RC
RELVDGATSLLVLGSSLTVMSGLRFVRQAAQ-GKPVLIVNRDP-RGDRHAVTRLTLPLGTALTALAARLDVP-------
>tr|A0A0N1H1I0|A0A0N1H1I0_9ACTN NAD-dependent protein deacetylase OS=Actinobacteria bacterium OV450 GN=cobB PE=3 SV=1
------------------------------------L-SAGGVLVVTGAGISTESGIPDYRSE----SLSR-HTPMTYQDFTGSARRYWARSHLGWRTF-
-ARARPNAGHRAVAAFGRH--LLAGMITQNVDGLHQAAG-DGVVELHGGLDRVVCL-CGAVRPRRELARLDVPCTLCGG--ILKPDVVFFGEAVG---QC
RELVREATSLLVLGSSLTVMSGLRFVRQAAE-GKPVLIVNRDP-RGDQHAVTRVALPLGAALTAVAGRLGLP-------
>tr|B5HZ02|B5HZ02_9ACTN NAD-dependent protein deacetylase OS=Streptomyces sviceus ATCC 29083 GN=cobB PE=3 SV=1
------------------------------------L-NAGGVLVLTGAGISTESGIPAYRGE----SLSR-HTPMTYQDFTASPRRYWARSHLGWRTF-
-GRARPNAGHRAVATFARH--LLSGAITQNVDGLHQAAG-EGVVELHGSLARVRCL-CDAITSRRDLARLGLPCADCGG--ILKPDVVFFGETVA---HC
RQLVRTATSLLVLGSSLTVMSGLRFVRQAAQ-DKRVLIINRDP-RGDQLAHTRVSLALGAALSHVADALNLS-------
>tr|H2JN42|H2JN42_STRHJ NAD-dependent protein deacetylase OS=Streptomyces hygroscopicus subsp. jinggangensis (strain 5008) GN=cobB PE=3 SV=1
------------------------------------L-SAGGVLVLSGAGISTESGIPDYRGE----SLSR-HTPMTYQEFTASARRYWARSHLGWRTF-
-GRARPNAGHRAVAAFGRH--LLSGVITQNVDSLHQAAG-EGVVELHGSLDRVVCL-CGAFSARRELARLDLPCVICGG--ILKPDVVFFGEAVQ---QC
REMVREAASLLVLGSSLTVMSGLRFVRQAAQ-GTPVLIINRDQ-RGDRHALTRVALPLGRALTAVADRLGIP-------
>tr|A0A0F4KNB2|A0A0F4KNB2_9ACTN NAD-dependent protein deacetylase OS=Streptomyces sp. NRRL S-444 GN=cobB PE=3 SV=1
------------------------------------L-RTGGVLVLSGAGMSTESGIPDYRGK----SLSR-HTPMTYQEFTASARRYWARSHLGWRTF-
-GRARPNPGHRAVAAFGRH--LLSGVITQNVDGLHQAAG-QGVVELHGGLDRVVCL-CGVSSSRRELARLDVPCSRCGG--ILKPDVVFFGEAVG---RC
RELVGEATSLLVLGSSLTVMSGLRFVRQAAQ-GKPVLIVNRDP-RGDRHAVTRVALPLGRTLTTLANRLDIP-------
>tr|A0A0G3ANC7|A0A0G3ANC7_9ACTN NAD-dependent protein deacetylase OS=Streptomyces incarnatus GN=cobB PE=3 SV=1
------------------------------------L-STGGVLVLSGAGISTDSGIPDYRGV----SLSR-HTPMTYQDFTASARRYWARSHLGWRTF-
-HRAGPNAGHRAVAAFGRH--LLSGVITQNVDGLHQAAG-DGVVELHGSLDRVVCL-CGAFSPRRALARLDVSCTICGG--ILKPDVVFFGEAVR---HC
RRLVREAASLLVLGSSLTVMSGLRFVRQAAQ-GKPVLIVNRDP-RGDRHAVTRVALPLGPALTSVADRLGIT-------
>tr|A0A021VV88|A0A021VV88_9CELL NAD-dependent deacetylase (Fragment) OS=Actinotalea ferrariae CF5-4 GN=N866_04015 PE=3 SV=1
------------------------------------L-RGRRLAVLTGAGVSTDSGIPDYRGP----S--PPRRPMTFQQFVADARTYWARNHVGWRYV-
-HRTRPNAGHEALARMEAQ--VVVGLITQNVDRLHTLAG-RSVIDLHGTYAEIVCL-CGDRTTRDALARLGADCE-CDG--MLKPDIVYFGESVE---RA
YALVDEADALLVAGSSLAVMSGLRFVRHAAR-GRPVVIVNRGA-RADVEATLRVHAGTSHLLPALADRLAAH-------
>tr|A0A0A0C8V2|A0A0A0C8V2_9CELL NAD-dependent protein deacetylase OS=Actinotalea fermentans ATCC 43279 = JCM 9966 = DSM 3133 GN=cobB PE=3 SV=1
------------------------------------L-TGRRLAVLTGAGISTDSGIPDYRGP----S--PPRRPMTYQQFVGDPRTYWARNHVGWRHV-
-HRTLPNPGHEALARLEAR--VVVGVVTQNVDRLHQAAG-RRVVDLHGTYAEVVCL-CGRRTTRDELARLGADCT-CGG--ILKPDITYFGEQVE---AA
FTLVDDADALLVAGSSLTVLSGRRYVTHAAR-GRPVVVVNRGQ-RGDALAAVKIEAGTTPTLLALERLL----------
>tr|A0A024H177|A0A024H177_9MICC Sir2 family protein OS=Arthrobacter siccitolerans GN=cobB PE=4 SV=1
------------------------------------L-AGRQFVLLTGAGLSTDSGIPDYRGA----S--PPRTPMTYQEFVKDARRYWARNHIGWSHL-
-RHADPNQGHYAAAELERR--YLTGLITQNVDRLHEDAG-VNVVDLHGRYDQVVCL-CRRTYSRRLLAVLSAVCP-CGG--TLKPDFVYFGENVD---RS
YRMVDEADALVAAGSSLTVMSGLRFVRHAAK-GKPVIIINRGD-RGDDKATIKLDAGVSESLAWLAAGLPPL-------
>tr|A0A0Q5IKY5|A0A0Q5IKY5_9MICC NAD-dependent deacetylase OS=Arthrobacter sp. Leaf141 GN=ASF72_10325 PE=4 SV=1
------------------------------------L-AGLRLAVLTGAGLSTDSGIPDYRGP----S--APRKPMTYQEFTKDARRYWARNHIGWSHL-
-RHADPNEGHFALARMEQR--LLTGLITQNVDRLHEDAG-TNVVDLHGRYDRVVCL-CHRNYSRQLLAMLTAVCP-CGG--VLKPDFVYFGENVD---RS
YAMVDDAEALVVAGSSLTVMSGLRFVRHAAK-GKPVVIINRGA-RGDDKATLKLESGVSESLTWLESELPTP-------
>tr|B8HA76|B8HA76_ARTCA NAD-dependent protein deacetylase OS=Arthrobacter chlorophenolicus (strain ATCC 700700 / DSM 12829 / JCM 12360 / NCIMB 13794 / 
------------------------------------L-SGAPFALLTGAGLSTDSGIPDYRGP----S--PPRSPMTYQEFVRDPQRYWARNHIGWSHL-
-RHADPNHGHLAAAELERR--YLTGLITQNVDRLHEDAG-TNVVDLHGRYDQVVCL-CGRTYSRGLLAMLSAVCP-CGG--TLKPDFVYFGENVD---RS
YAIVDEAAALLVAGSSLTVMSGLRFVRHAAK-GKPVVIINRGE-RGDDKATIKLEAGVSESLRWLAQHLSPL-------
>tr|A0A0D1C8B5|A0A0D1C8B5_9MICC NAD-dependent protein deacetylase OS=Arthrobacter sp. SPG23 GN=cobB PE=3 SV=1
------------------------------------I-AGTRFALLTGAGLSTDSGIPDYRGP----A--APRAPMTYQEFIGHAQRYWARNHIGWSHL-
-RRADPNDGHAAAARLERR--LLTGLITQNVDRLHEDAG-VNVVDLHGRFDRVACL-CARRYSRTLLAVLSAHCP-CGG--TLKPDFVYFGENVD---RS
YAMVDEAGALVVAGSSLTVMSGLRFVRHAAK-QKPVVIINRGA-RGDDLATIKLEAGVSESLTWLAAELPDL-------
>tr|A0A0K2R498|A0A0K2R498_9MICC NAD-dependent protein deacetylase OS=Arthrobacter sp. Hiyo4 GN=cobB PE=3 SV=1
------------------------------------L-SGKRLALLTGAGLSTDSGIPDYRGP----A--VPRSPMTYQEFVRDAQRYWARNHIGWSHL-
-RHADPNPGHRAAAELERR--LLTGLITQNVDRLHEDAG-RNVIDLHGRYDQVVCL-CQRTYTRHLLAILSAACP-CGG--MLKPDFVYFGENVE---AA
YAMVDSAAALLVAGSSLTVMSGLRFVRHAVK-GKPVVIINRGG-RGDQYATIKLDAGVSEALTWLAAELPDL-------
>tr|A0A0B4DMF8|A0A0B4DMF8_9MICC NAD-dependent protein deacetylase OS=Arthrobacter phenanthrenivorans GN=cobB PE=3 SV=1
------------------------------------L-AGGRFALLTGAGLSTDSGIPDYRGP----S--PPRSPMTYQEFVRNAQRYWARNHIGWSHM-
-RHADPNPGHFSAAELERR--YLTGLITQNVDRLHQDAG-SNVVDLHGRYDQVICL-CGRTYSRRLLAVFSAVCP-CGG--TLKPDFVYFGENVD---RS
YAMVDRAEALVVAGSSLTVMSGLRFVRHAAK-AKPVVIINRGA-RGDDKATIKLEAGVSQALAYLAAELPAL-------
>tr|L8TXX9|L8TXX9_9MICC Silent information regulator protein Sir2 OS=Arthrobacter nitrophenolicus GN=G205_01464 PE=4 SV=1
------------------------------------L-GGMRFALLTGAGLSTDSGIPDYRGP----S--PPRTPMTYQEFVREAQRYWARNHIGWSHL-
-RHADPNPGHFAAAHLERR--YLTGLITQNVDRLHEDAG-SNVIDLHGRFDQVVCL-CTRTYSRKLLAMLSAACP-CGG--TLKPDFVYFGENVD---KA
YAMVDAAAAVVVAGSSLTVMSGLRFVRHAAK-GKPVVIINRGE-RGDDKATIKLEAGVSESLTWLAGNLPPL-------
>tr|A0A0Q9NQ26|A0A0Q9NQ26_9MICC NAD-dependent deacetylase OS=Arthrobacter sp. Soil763 GN=ASG71_09205 PE=4 SV=1
------------------------------------L-AGERFALLTGAGLSTDSGIPDYRGP----A--APRAPMTYQEFIGAPRRYWARNHIGWSRM-
-RRADPNDGHAAAALLEQR--LLTGLITQNVDRLHEDAG-VNVVDLHGRFDQVTCL-CHRRYSRTLLAVLGANCP-CGG--TLKPDFVYFGENVD---RS
YAMVDAAAALLVAGSSLTVMSGLRFVRHAAK-GKDVVIINRGP-RGDDLATIKLEAGVSESLSWLAAELPGL-------
>tr|F0M500|F0M500_ARTPP NAD-dependent protein deacetylase OS=Arthrobacter phenanthrenivorans (strain DSM 18606 / JCM 16027 / LMG 23796 / Sphe3) GN=cobB
------------------------------------L-ERGRFALLTGAGLSTDSGIPDYRGP----S--PPRSPMTYQEFVKAAQRYWARNHIGWSHL-
-RRADPNQGHYAVAELERR--RLTGLITQNVDRLHQDAG-INVVDLHGRYDQVVCL-CRRVYSRRLLAMLSAVCP-CGG--TLKPDFVYFGENVD---TS
YRMVDDASALVVAGSSLTVMSGLRFVRHAAK-GKPVVIINRGV-RGDDKATIKLEAGVSESLAWLAAELPRL-------
>tr|K9ADF4|K9ADF4_9MICO Silent information regulator protein Sir2 OS=Brevibacterium casei S18 GN=C272_14955 PE=4 SV=1
------------------------------------H-SPSDWAVLTGAGMSTDSGIPDYRGP----A--DPRRPMTIQNFLSHPARYWARSWVGWPRM-
-RWAEPNAGHLALARLG-----VAGIITQNVDGLHQAAAKGPVIDLHGSLDRVVCL-SGHLFDRDWVQQLHLDCPICGG--LLKPDVVYFGDAVA---AA
AEICETASGLVVLGTSLAVLSGLRFVRAAAK-GKPVVIVTDGP-RGDELADYRSTSRVTDFVTAWASRGIQT-------
>tr|A0A0B9A9H6|A0A0B9A9H6_BRELN Silent information regulator protein Sir2 OS=Brevibacterium linens GN=AE0388_2701 PE=4 SV=1
------------------------------------Y-SDADWAVLTGAGMSTDSGVPDYRGP----S--PPRNPMTIQTFLSHPARYWARSWMGWPRM-
-RSTQPNQAHLALAELS-----VGGIITQNVDGLHQAAAESPVIDLHGSLDRVICL-NGHLFDRDWVQRLGLDCPECGG--LLKPDVVYFGDSVA---AA
NRIADEAAGLVVLGSSLAVLSGLRFVRAAAK-GKPVVIVTDGP-RGDEFADFRSISRVADFVTTWARR-----------
>tr|W5TQ50|W5TQ50_9NOCA NAD-dependent protein deacetylase OS=Nocardia nova SH22a GN=cobB PE=3 SV=1
------------------------------------L-AGRRIVVLTGAGVSTDSGIPDYRGP----S--PPRTPMTYQQFVGDPQRYWARNHVGWRRM-
-DAARPNTGHRMLARLERG--AVTGLITQNVDLLHTKAG-RRVIDLHGSYAQVRCL-CDDLTSRMTLARLDVDCA-CGG--MLKPDIVYFGENVD---AA
FSLVDAADAILVAGSSLTVMSGLRFVRHAAK-GKPIVIVNRGR-RGDELATVRMDSGCSATLTALAETLAPI-------
>tr|A0A0Q7NZ58|A0A0Q7NZ58_9NOCA NAD-dependent deacetylase OS=Nocardia sp. Root136 GN=ASD42_02845 PE=4 SV=1
------------------------------------L-SGRRTVVISGAGLSTDSGIPDYRGP----S--PARTPMTYQQFVGDPQRYWARNHIGWRRM-
-DAARPNPGHRALARLERA--AVSGVITQNVDLLHTKAG-RRVIDLHGTYARVRCL-CANLISRMTLAHLRVDCM-CGG--MLKPDIVYFGENVD---AA
FDMVEQARAILVAGSSLTVMSGLRFVRRAAK-GVPVVIVNRGR-RGDELATLRIDAGCSETLCALAELGC---------
>tr|H6R827|H6R827_NOCCG NAD-dependent protein deacetylase OS=Nocardia cyriacigeorgica (strain GUH-2) GN=cobB PE=3 SV=1
------------------------------------I-GGRRMAVLTGAGLSTDSGIPDYRSP----S--PPRTPMTFQQFVGDPQRYWARNHVGWRRM-
-DASRPNPGHRALARLERL--VVSGLITQNVDLLHTKAG-RRVIDLHGSYARVRCL-CDHLVSRMSLARLAVGCV-CGG--ILKPDIVYFGENVQ---AA
YDLVDEAEVLLVAGSSLTVMSGLRFVRHAAK-GKAVLIVNRGH-RGHDLATLTVDAGCSPTLTALADHLAVR-------
>tr|F6EQX1|F6EQX1_AMYSD NAD-dependent protein deacetylase OS=Amycolicicoccus subflavus (strain DSM 45089 / DQS3-9A1) GN=cobB PE=3 SV=1
------------------------------------L-AGQRILALTGAGISTDSGVPDYRGP----S--PKRTPMTFQQFVGSAQRYWARNHLGWQYI-
-ESRSPNPGHLALAELERS--AVAHLITQNVDLLHTKAG-RTVIDLHGTYRSVVCL-CGSTTDRKALARLHAACV-CGG--ILKPDIVFFGESVE---HA
YAAVDDATALLVAGSSLTVMSGLRFVRHAAK-GKPIVIVNRGE-RGDDLAALKLNAGCTEVLTTLARLLT---------
>tr|A0A0H5P7F8|A0A0H5P7F8_NOCFR NAD-dependent protein deacetylase OS=Nocardia farcinica GN=cobB_2 PE=3 SV=1
------------------------------------L-AGLRVAVLTGAGLSTDSGIPDYRGP----S--PPRNPMTYQQFVGDPRRYWARNHIGWRRM-
-DAARPNPGHRALARLERL--AVGGVITQNVDLLHTKAG-RRVIDLHGTYARVRCL-CGALMSRMTLALLHVDCA-CGG--MLKPDIVYFGENVD---AA
YDLVDSCDALLVAGSSLTVMSGLRFVRRAAR-GHPVVIVNRGP-RGDDLATLRLDAGCSPTLAAFAAHCGDT-------
>tr|U5EH89|U5EH89_NOCAS NAD-dependent protein deacetylase OS=Nocardia asteroides NBRC 15531 GN=cobB PE=3 SV=1
------------------------------------L-AGRRLVVITGAGLSTDSGIPDYRGP----S--PPRNPMTYQQFVGDAQRYWARNHLGWRRM-
-DAARPNPGHRAVAALERA--VVSGVITQNVDLLHTKAG-RRVIDLHGTYARVRCL-CAATISRMTLARLRLDCA-CGG--MLKPDIVYFGESVD---AA
FALVDDAQAVLVAGSTLTVMSGLRFVRRAAK-GVPVVIVNRGA-RADELATVRVEAGCSETLCAFAERLPAP-------
>tr|A0A034UB67|A0A034UB67_9NOCA NAD-dependent protein deacetylase OS=Nocardia brasiliensis NBRC 14402 GN=cobB PE=3 SV=1
------------------------------------L-AGRRIAVLTGAGVSTDSGIPDYRGP----S--PPRNPMTYQQFVGDPQRYWARNHVGWRRM-
-DASRPNPGHRALAELERM--VVTGLITQNVDLLHTKAG-RRVIDLHGTYAQVRCL-CAARISRMALAQLGVDCA-CGG--MLKPDIVYFGENVD---AA
FDLVDAADALLVAGSSLTVMSGLRFVRHAAR-GKPVVIINRGE-RGDALATCTLDAGCSEALPALAQTLGGV-------
>tr|C8XG88|C8XG88_NAKMY NAD-dependent protein deacetylase OS=Nakamurella multipartita (strain ATCC 700099 / DSM 44233 / JCM 9543 / Y-104) GN=cobB PE=3 
------------------------------------L-AGRRLVVLTGAGLSTDSGIPDYRGP----S--PPRSPMTYDEFVSGSQRYWARSHIGWQRL-
-GSAQPNQGHHALAALESA--VVRTLITQNVDGLHRAAG-RTVIDLHGRIDQVICL-CGVLSGRLELHRLEVDCRVCGG--VLKPDVVFFGENVA---QV
YTAMTTGQALLVAGSSLTVMSGLRFVRHAAK-GWPIVIVNRGI-RGDPLARGRVDAGCTPTLTALAERLTG--------
>tr|S4XIW8|S4XIW8_SORCE NAD-dependent protein deacetylase OS=Sorangium cellulosum So0157-2 GN=cobB PE=3 SV=1
------------------------------------L-RGKRFVALTGAGCSTESGIPDYRGP----TRRRARNPIQGREFSSSAQRYWARAVIGWERF-
-SRAEPNPAHRALARLEQG--LIEGLITQNVDGLHQAAG-RRVIELHGTLAEVACL-CGAMEPRAALQRLGPPCLRCDG--PLKPRVVFFGENVP---AA
FALVDAAEALLVVGSSLAVFSGYRFVLRAAQ-GIPIAMVNLGS-RGEELGALKVEARAGEVLPRLADALAGA-------
>tr|A0A0H4WYC9|A0A0H4WYC9_9DELT NAD-dependent protein deacetylase OS=Myxococcus sp. (contaminant ex DSM 436) GN=cobB PE=3 SV=1
------------------------------------L-RRRRTVVLTGAGCSTESGIPDYRGP----TRARARNPIQHREFMTRPARYWARSLMGWPRF-
-SSARPNAAHAALAALEQA--HVPGLITQNVDQLHHAAG-SRVIELHGALARVRCL-CGAQERRVDLQRLSPACRLCDG--PLKPDVVFFGDNVP---AA
FALLEEGDALLVVGSSLAIFSGYRFLVRASE-RMPIAILNMGE-RGVELADVHLEARAGDALPRLVEALARG-------
>tr|Q08XM5|Q08XM5_STIAD NAD-dependent protein deacetylase OS=Stigmatella aurantiaca (strain DW4/3-1) GN=cobB PE=3 SV=1
------------------------------------M-RGRRAVVLTGAGCSTESGIPDYRGP----TRARARNPIQHMEFLHRATRYWARSLLGWPRF-
-SSAQPNAAHHALATLERA--HVQGLITQNVDRLHHAAG-TRVIELHGALAEVRCL-CHTREARASLQRLAADCLHCDG--PLKPDVVFFGDNVP---AA
FALLEEGDVLLVVGSSLAIFSGYRFVTRAAE-GMPIALVNIGE-RGAALANVVLEARAGEVLPLLAERLAQG-------
>tr|D0LKF6|D0LKF6_HALO1 NAD-dependent protein deacetylase OS=Haliangium ochraceum (strain DSM 14365 / JCM 11303 / SMP-2) GN=cobB PE=3 SV=1
------------------------------------L-AGRRVVALTGAGCSTESGIPDYRGP----ARRA-RNPIQYRAFLGRAQRYWARSFIGWQRV-
-ARATPNGCHHAVTELERA--LLVGVITQNVDGLHQAAG-DRVVELHGSLAEVRCL-CDEIEPRRDLQRLGLDCLRCRG--VLKPNVVFFGEHVD---AA
WELFDEAEALLVLGSSLTVFSGYRFVRRAAE-QVPVAIINRGP-RGDGEAAVLVDAALGQVMPALSAALLRA-------
>tr|S9PAZ1|S9PAZ1_9DELT NAD-dependent protein deacetylase OS=Cystobacter fuscus DSM 2262 GN=cobB PE=3 SV=1
------------------------------------L-RGRRVVVLTGAGCSTESGIPDYRGP----TRARARNPIQHREFLARPARYWARSLIGWPRF-
-SSARPNAAHQALAALEDA--HVLGLITQNVDRLHHAAG-RRVIELHGALARVRCL-CGALEPREQLQRLAAACLDCEG--TLKPDVVFFGDNVP---EA
FALLEEGDAFLVVGSSLAIYSGYRFLQRAVD-RMPVGLINIGE-RGHEWMEVRVEARAGEVLPRLASALGAG-------
>tr|A0A0Q5IZA9|A0A0Q5IZA9_9MICC NAD-dependent deacetylase OS=Arthrobacter sp. Leaf145 GN=ASF74_04625 PE=4 SV=1
------------------------------------L-QGQRLAVLTGAGLSTDSGIPDYRGP----S--APRNPMTYQEFIGSERRYWARNHIGWSHL-
-RHADPNAGHAAVALMERR--LLTGLITQNVDRLHEDAG-VNVVDLHGRFDQVICL-HGHTFSRQLIAILSAVCP-CGG--ILKPDFVYFGENVD---RA
YGMVDDAEALLVAGSSLTVQSGLRFVRHASK-GKPVVIINRGI-RGDELASVKLELGVSGALDYLARALPDL-------
>tr|B2GG03|B2GG03_KOCRD NAD-dependent deacetylase OS=Kocuria rhizophila (strain ATCC 9341 / DSM 348 / NBRC 103217 / DC2201) GN=KRH_10840 PE=4 SV=1
------------------------------------L-VGRRIAVLTGAGVSTPSGIPDYRGP----A--KPRTPMTYQEFMGSVRHYWARNQYGWHFV-
-AQARPSAAHTALAGMEAA--VVDGIITQNIDRLHQKAG-LAVVDLHGTYAWVVCT-CGSRFPREQVSYLGWDCPVCQG--VLKPDVVFFGENAL---LA
RRMVGRADALLVAGSSLTVNSGRRFVRQAAR-ATPVVIVNHGV-GADDLAALKIDAPVGQFLTELAALLCP--------
>tr|A0A0Q9MQU0|A0A0Q9MQU0_9MICC NAD-dependent deacetylase OS=Arthrobacter sp. Soil736 GN=ASG92_16120 PE=4 SV=1
------------------------------------L-SGLRMALLTGAGLSTDSGIPDYRGP----S--PPRSPMTYQEFVGDAQRYWARNHIGWSHL-
-RRADPNAGHAAVTALERR--LLTGLITQNVDRLHEDAG-VNVVDLHGRFDQVICL-CKRTYSRQLLAVLSARCP-CGG--VLKPDFVYFGENVE---RA
YAIVDEAGALLVAGSSLSVMSGLRFVRHAAK-GKPVVIINRGE-RGDDLATIKLVAGVSETLAWLAAELPGL-------
>tr|A0A0K2RS70|A0A0K2RS70_9MICC NAD-dependent protein deacetylase OS=Arthrobacter sp. Hiyo8 GN=cobB PE=3 SV=1
------------------------------------L-GGKRLAVLTGAGLSTDSGIPDYRGP----A--APRNPMTYQEFIGSPRRYWARNHLGWSHL-
-RHADPNAGHAAVALLERR--LMTGLITQNVDRLHEDAG-INVVDLHGRYDRVICL-EGHLFTRRLVAILSAVCP-CGG--TLKPDFVYFGENVG---RA
YSMVDEAGALLVAGSSLTVMSGLRFVRHAAK-GKPVVIINRGP-RGDGFADLKVEVGVSGALAWLAAELPDL-------
>tr|U1Y161|U1Y161_9MICC NAD-dependent deacetylase OS=Arthrobacter sp. AK-YN10 GN=M707_23215 PE=4 SV=1
------------------------------------L-ACKRLAVLTGAGLSTDSGIPDYRGP----S--APRKPMTYQEFVRSARRYWARNHIGWSHL-
-RRANPNVGHAAVAAMEQR--LLSGLITQNVDRLHEDAG-VNVVDLHGRFDQVICL-QGHTFSRKLLAILSAVCP-CGA--TLKPDFVYFGENVD---RA
YGMVDDAGALLVAGSSLTVMSGLRFVRHAAK-GKPVVIINRGI-RGDEFATLKLDLGVSGALSYLAGHLPDL-------
>tr|A0A0K3AVL1|A0A0K3AVL1_9PSEU NAD-dependent protein deacetylase OS=Kibdelosporangium sp. MJ126-NF4 GN=cobB PE=3 SV=1
------------------------------------L-AEGAVLVLSGAGLSTESGIPDYRGA----SLRR-NTPMTYDEFVGSVRRYWARSHVGWRTI-
-ARAHPNDGHRAVAALCAG--LVSSVITQNVDGLHQAAG-PGVVELHGSLDRVVCL-CRATSPREELDRLEVSCADCET-GVLKPDVVFFGENVS---QC
YRLVDEAKALVVLGSSLTVMSGLRFVRYAAK-DKPVAIVNRGR-RGDEYAAIRVDLPLGQGLTDLTRLVGAH-------
>tr|W5WB77|W5WB77_9PSEU NAD-dependent protein deacetylase OS=Kutzneria albida DSM 43870 GN=cobB PE=3 SV=1
------------------------------------V-AAGGVLVLSGAGLSTESGIPDYRGS----SLRR-HTPMTYQEFATSERRYWARSHLGWRTI-
-ARAQPNSGHRAVAQMRAR--YLDGVLTQNVDGLHQAAG-PGVVELHGSLDRVVCL-CRRTSSREELDRLGVDCADCAG-GVLKPDVVFFGENVD---QC
YQLVDQASALLVLGSSLTVMSGLRFVRYAAK-GKPVLIVNQGV-RGDPHAAVRVDLPLGQALTELAGRLA---------
>tr|A0A0N0AR78|A0A0N0AR78_9PSEU NAD-dependent protein deacetylase OS=Saccharothrix sp. NRRL B-16348 GN=cobB PE=3 SV=1
------------------------------------V-ADGRVVVLSGAGLSTESGIPDYRGA----SLRK-HTPMTYDEFVGSARRYWARSHLGWRTI-
-ARAAPNTGHHAVAELHAR--HLTGVITQNVDGLHQAAG-PDVVELHGSLDRVVCL-CRAVSAREDLDRFSVDCAGCAG-GVLKPDVVFFGENVE---RC
YRLVDEADALLVLGSSLTVMSGLRFVRRAAT-GKPVLIVNKGE-RGDVHATVRVDLPLGQALTSLLDRL----------
>tr|A0A0N9I050|A0A0N9I050_9PSEU Uncharacterized protein OS=Kibdelosporangium phytohabitans GN=AOZ06_32365 PE=4 SV=1
------------------------------------V-AGGSVAVLSGAGLSTESGIPDYRGA----SLRR-AAPMTYDEFVGSVRRYWARSHVGWRTI-
-ARAHPNDGHHAVAALCAE--YVAGVITQNVDGLHQAAG-PGVVELHGSLDRVVCL-CRARSPREELDRLEVSCADCES-GVLKPDVVFFGENVA---QC
YRMVDEARALVVLGSSLTVMSGLRFVRHAAR-GKPVAIVNRGR-RGDEYAGIRVDLPLGRGLTDLTRLVGIR-------
>tr|R1HUY3|R1HUY3_9PSEU NAD-dependent protein deacetylase OS=Amycolatopsis vancoresmycina DSM 44592 GN=cobB PE=3 SV=1
------------------------------------V-ARGGVAVLSGAGLSTESGIPDYRGE----SLRR-HTPMTYDEFVTSAQRYWARSHLGWRTI-
-ARADPNDGHRAVTALREA--YVSGVITQNVDGLHQAAG-TDAVELHGSLDRVICL-CRRTSPRAELDRLGVPCEACDG--VLKPDVVFFGENVP---QC
YRLVDAAAALLVLGSSLTVMSGLRFVRHAAA-GKPVVIVNRGE-RGDRYASVRVDRPLGDALTELVGRLGED-------
>tr|D9UW23|D9UW23_9ACTN NAD-dependent protein deacetylase OS=Streptomyces sp. AA4 GN=cobB PE=3 SV=1
------------------------------------V-AGRDVLVLSGAGLSTESGIPDYRGE----SLRK-HTPMTYGEFVSSEQRYWARSHLGWRTI-
-ARAAPNDGHRAVSALRAG--WVSGVITQNVDGLHRAAG-PGVVELHGNLDRVVCL-CRRTTPREDLDRLAVPCTSCSG--VLKPDVVFFGENVA---RC
YRMVDEASAVLVLGSSLTVMSGLRFVRRAAK-GKPVAIVNRGQ-RGDEHAAVRADLPLGPALTELLAVLENA-------
>tr|A0A076MU75|A0A076MU75_AMYME NAD-dependent protein deacetylase OS=Amycolatopsis methanolica 239 GN=cobB PE=3 SV=1
------------------------------------A-GAGGVVVLSGAGLSTESGIPDYRGV----SLRR-HTPMTYQEFVAAERRYWARSHLGWRTI-
-ARAHPNDGHRAVAALRSA--VVGGVITQNVDGLHQAAG-PDVVELHGSLDRVVCL-CRALSPREELDRLGVPCTVCAG--VLKPDVVFFGENVS---QC
FRLVDEASALLVLGSSLTVMSGLRFVRRAAE-GKPVAIINQGP-RGDKYADVRVDLPLGRALTDLVTRLAA--------
>tr|C7PYL4|C7PYL4_CATAD NAD-dependent protein deacetylase OS=Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897) GN=co
------------------------------------V-AGRGVVVLSGAGLSTESGIPDYRGK----ALRR-HTPMTYEDFAGSAQRYWARSHLGWRAM-
-AGAQPNVGHRAVAALRAS--HVDGVITQNVDGLHQAAG-PEVVDLHGSLDRVICL-CGVFSERTELERLRVDCDSCGE-GVLKPDVVFFGENVA---RC
KELVDGAAALLVLGSSLTVMSGLRFVRRAAE-GKPVVIVNQGL-RGDRYASERIEAPLGAALVELVGRVGAA-------
>tr|H6MXX1|H6MXX1_GORPV Putative NAD-dependent deacetylase OS=Gordonia polyisoprenivorans (strain DSM 44266 / VH2) GN=GPOL_c19640 PE=4 SV=1
------------------------------------L-DGARITALTGAGLSTDSGIPDYRSP----A--PARTPMTVQMFLSSPRHYWARNHLGWRHM-
-DAATPNAGHHALAELGRQ--RLTGVITQNVDMLHTKAR-RRVIELHGCYGRVRCL-CDATLSRHRLAMLDAPCPRCGG--ILKPDIVYFGENAE---QS
FAMIDESDALLVAGSSLTVMSGLRFARYAHR-SKTLVVVNRGA-RADHIADLKIDHFCGVVLPALAQWGRAD-------
>tr|M7AB36|M7AB36_9ACTN NAD-dependent protein deacetylase OS=Gordonia sp. NB4-1Y GN=cobB PE=3 SV=1
------------------------------------L-DGARIAALTGAGISTDSGIPDYRSP----A--PIRTPMTVQMFLSSPRHYWARNHLGWRHM-
-DAAQPNAGHHALTALQRQ--SLNGVITQNVDMLHTKAG-RGVIDLHGSYGRVRCL-CGWIVSRHRLAMLDAECP-CGG--ILKPDIVYFGENAD---QS
FSLVDASDALLVAGSSLTVMSGLRFARHAHR-GKVLVVVNRGG-RADDIADLKVDHYCGVVLPALAG------------
>tr|G7GL32|G7GL32_9ACTN NAD-dependent protein deacetylase OS=Gordonia amarae NBRC 15530 GN=cobB PE=3 SV=1
------------------------------------L-REARITALTGAGMSTDSGIPDYRSP----A--PPRTPMTLEMFLSSPRHYWARNHLGWRHM-
-DAARPNDGHHALTRLQRQ--RLTGVITQNVDMLHTKAG-RRVVELHGCYRRVRCL-CGALSSRQALARLDADCE-CGG--ILKPDIVYFGENAS---QA
FSLVNDSDALLVAGSSLTVMSGLRFVRHAHR-GKPVVIVNRGA-RADDLADLKIDHYCSTVLSALADD-----------
>tr|H5TZC5|H5TZC5_9ACTN NAD-dependent deacetylase OS=Gordonia sputi NBRC 100414 GN=cobB PE=4 SV=1
------------------------------------L-DGRRVVALTGAGISTDSGIPDYRSP----A--PVRTPMTLEMFLSSPRHYWARNHLGWRHM-
-DAARPNASHHTLTQLQRR--ALTTVITQNVDMLHTKAA-RGVIELHGCYGRVRCL-CGDTISRRGLATLDADCSMCGG--TLKPDIVYFGENAT---QA
FSAVDDADAMIVVGSSLTVMSGLRFARHAHR-GKPLVVINRGI-RADDIADLKIDHYCGSVLAALTPHAAA--------
>tr|L7KPZ2|L7KPZ2_9ACTN NAD-dependent protein deacetylase OS=Gordonia aichiensis NBRC 108223 GN=cobB PE=3 SV=1
------------------------------------L-DGRRCVVLTGAGISTDSGIPDYRSP----A--PVRTPMTLEMFLSSPRHYWARNHLGWRHM-
-DAARPNASHHALTDLQRD--RVTTVITQNVDMLHTKAG-RGVIELHGCYGRVRCL-CGQTMSRRRLAALGADCAACGG--TLKPDIVYFGENAD---QA
FSAVDDADAMIVVGSSLTVMSGLRFARHAHR-GKPLVVINRGT-RADDIADLKIDHYCGEVLPALRRRPDRR-------
>tr|A0A0A1CX76|A0A0A1CX76_9MICC NAD-dependent protein deacetylase OS=Arthrobacter sp. PAMC25486 GN=ART_1145 PE=4 SV=1
------------------------------------L-RGVPFALLTGAGLSTDSGIPDYRGP----A--APRQPLTYQEFMGDPQRYWARNHIGWAHM-
-LGAKPNAGHYAAAALEHG--ALTGIITQNVDRLHEDAG-TNVVDLHGRFDQVVCM-CTNTYSRDFLAVLAAKCPLCGG--LLKPDFVFFGENVA---RS
FEMVDAAGALLVAGSSLTVMSGLRFVKKAAK-NKPVIIINRGE-RGDPQSTVKLEAGVGESLGRLVQLLGLD-------
>tr|A0A0B2BQX2|A0A0B2BQX2_9ACTN NAD-dependent protein deacetylase OS=Mumia flava GN=cobB PE=3 SV=1
------------------------------------L-RRGRVVVLTGAGISTDSGIPDYRGP----S--TPRTPMTYQEFVRTRQRYWARAHVGWRHM-
-TGAAPNTAHHALVALESA--VVDAVITQNVDGLHEAAG-RSLVTLHGRIADVVCL-CRARIARSALHRLAADCPGCGG--VLKPDVVFFGESVD---RC
RALVDEAATLLVVGSSLQVMSGLRFVRQAAK-GTPVVIVNRGP-RGDELATLRLDAGCAETLAPLAAALAA--------
>tr|A0A0M4M924|A0A0M4M924_9MICC NAD-dependent deacetylase OS=Arthrobacter sp. ERGS1:01 GN=AL755_14470 PE=4 SV=1
------------------------------------F-AGKPFALLTGAGLSTDSGIPDYRGP----A--APRKPVTYQEFTGDLQRYWARNHLGWAQM-
-HRAAPNAGHFAAAALERQ--ALTGIITQNVDRLHEDAG-ANVVDLHGRFDRVVCL-CGEVYSRDFIAILAASCPLCGG--MLKPDFVFFGENVD---RA
FAMVDSAGALLVAGSSLTVMSGLRFVRKAVK-GVPVAIVNRGA-RGDELADIKLEAGVGESLSYLSAALGP--------
>tr|A0A0M4QQ38|A0A0M4QQ38_9MICC NAD-dependent deacetylase OS=Arthrobacter alpinus GN=AOC05_09160 PE=4 SV=1
------------------------------------L-AAGKFALLTGAGLSTDSGIPDYRGP----A--APRKPLTYQEFVRDAQRYWARNHIGWATM-
-HHASPNAGHFAATALERQ--ALTGIITQNVDRLHESAG-MDVVDLHGRFDQIACL-CGNTYSRAFVAILTALCPLCGG--MLKPDFVFFGENVD---RA
FSMVDAAAALVVAGSSLTVMSGLRFVRKAAK-GKPVIIINRGA-RGDGLATVKLVAGVSESLSFLSRALESR-------
>tr|I8QG52|I8QG52_9ACTN NAD-dependent protein deacetylase OS=Frankia sp. QA3 GN=cobB PE=3 SV=1
------------------------------------V-AAGGVAVVSGAGISTDSGIPDYRGP----ALRR-HTPMTYQQFTKEPHRYWARSHAGWRQV-
-ARAEPNAGHRAVARLEQA--LVTGIVTQNVDELHQRAG-RHVIDLHGSLSRVVCS-CGEVSPRRDLDRLRVDCRGCGG-EQLEPDVVFFGATVP---QA
FDLVESARAVMILGSSLTVMSGYRFVLRAAE-GIPVAIVNQGP-RGDSRATVRVDAPLGSLLPRLAAAVTGG-------
>tr|D3D6B4|D3D6B4_9ACTN Silent information regulator protein Sir2 OS=Frankia sp. EUN1f GN=FrEUN1fDRAFT_5336 PE=4 SV=1
------------------------------------V-AAGGVAVLTGAGISTGSGIPDYRGP----SLRR-HTPMTYQQFTGDARRYWARSHVGWRHV-
-ALARPNPGHHAVAALEAA--LVDGVITQNVDGLHSAAG-RRVIDLHGSLARVRCR-CGVLSDRADLDRLGVGCVDCDG-D-LEPDVVFFGATVA---AA
VDLLARSRALLVLGSSLAVMSGYRFVLRAGE-GIPVGIVNQGP-RGDARAAFTLDAQLSTVLPRLATELAGA-------
>tr|Q2J993|Q2J993_FRASC NAD-dependent protein deacetylase OS=Frankia sp. (strain CcI3) GN=cobB PE=3 SV=1
------------------------------------V-AAGGVAVVTGAGISTDSGIPDYRGP----ALRR-HTPMTYQEFTDDPHRYWARSHAGWRRV-
-ARAEPNPGHRALARLEQD--LVTGVVTQNVDGLHQRAG-RRVIDLHGRLSRVLCR-CGDVSPRLELDRLAVGCRRCGG-DELEPDVVFFGATVP---EA
LRLVEGARALLILGSSLTVMSGYRFVLRAAE-DIPVAIVNQGP-RGDSRAAVRVDAPLGLLLPRLAAAVTPP-------
>tr|A0A0M0F8M4|A0A0M0F8M4_CELCE NAD-dependent protein deacetylase OS=Cellulosimicrobium cellulans F16 GN=cobB PE=3 SV=1
------------------------------------L-RGLRVTALTGAGLSTDSGIPDYRGP----S--PPRNPMTYQQFVQDERHYWARNHVGWQHV-
-HRTQPNAGHRALARLEDA--VLVGLITQNVDLLHEDAG-RNVIDLHGRYDRVICL-CGRVISREHLARLHAPCE-CGG--VLKPEIVYFGENVE---RA
YAMVDEGDALLVAGSSLTVMSGLRFVRHAAK-GKPVVIVNRGW-RGDPLATLKVDAGTTETLTTLAAALPR--------
>tr|D7B1X0|D7B1X0_NOCDD NAD-dependent protein deacetylase OS=Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 1048
------------------------------------L-GSGPVVALTGAGLSTDSGIPDYRGP----S--PPRKPMTYQQFVGDARHYWARNHVGWRHV-
-HRTRPNDGHRALAALEAG--ALAGVITQNVDTLHGAAG-RRVIDLHGRYDRVVCL-CSSVTSRESLARLGADCE-CGG--VLKPDIVYFGENVA---AG
YAMVDGARALLVAGSSLTVFSGRRYVKRAVE-GKPVVILNRGA-RADDVAALTVDAGCSEVLTALVRAYEAE-------
>tr|A0A0A0B9A8|A0A0A0B9A8_9CELL NAD-dependent protein deacetylase OS=Cellulomonas cellasea DSM 20118 GN=cobB PE=3 SV=1
------------------------------------L-AGRRVTALTGAGVSTDSGIPDYRGP----S--PPRNPMTFQQFVGDPRHYWARNHVGWRHM-
-RRTEPNAGHRALAELEAR--VLVGVITQNVDLLHEEAG-VDVIDLHGRYDRVVCL-CGHVVSRASLDRLHADCE-CDG--MLKPEIVYFGENVE---RA
FAMVDAADALLVAGSSLTVMSGLRFVRHAAK-GMPVVIVNRGQ-RGDPLATLKVDAGTSEVLTELSRSLPPV-------
>tr|F6FV37|F6FV37_ISOV2 NAD-dependent protein deacetylase OS=Isoptericola variabilis (strain 225) GN=cobB PE=3 SV=1
------------------------------------L-AGRTITALTGAGVSTDSGIPDYRGP----S--PPRNPMTYEQFVSDERHYWARNHVGWQHV-
-RRTHPNAGHRALARLEER--VVHGVITQNVDLLHEEAG-RNVIDLHGRYDRVVCL-CGRVISRAHLARLHAPCE-CGG--VLKPEIVYFGENVE---RA
YAMVDAADALLVAGSSLTVMSGLRFVRHAAK-EKPIVIVNRGE-RGDPLATVKVDAGVTETLTELVERL----------
>tr|D1BUL5|D1BUL5_XYLCX NAD-dependent protein deacetylase OS=Xylanimonas cellulosilytica (strain DSM 15894 / CECT 5975 / LMG 20990 / XIL07) GN=cobB PE=
------------------------------------L-RGRTFTALTGAGISTDSGIPDYRSP----S--PPRNPMTYEQFVGDERHYWARNHVGWQHV-
-RRTRPNDGHRALAALEAA--IVRGVITQNVDLLHEDAG-RRVIDLHGRYDRVACL-CGRVISRARLARLHAPCE-CGG--VLKPEIVYFGETVE---RA
YAMVDDADALVVAGTSLTVMSGLRFVRHAAK-GTPVVIINRGP-RGDPLATLKLDAGTTETLTTLAATLTSR-------
>tr|K9EEJ3|K9EEJ3_9ACTO Uncharacterized protein OS=Actinobaculum massiliense ACS-171-V-Col2 GN=HMPREF9233_00864 PE=4 SV=1
------------------------------------L-AGAPFAVITGAGISTDSGMPDYRSP----S--APRRPMTYQQFMADPQHYWARNHSGWLRP-
-FTSIPNEGHLALAELERA--LVTGIITQNVDRLHSRAG-RNVVDLHGRYDRVLCT-CGKAFRRAVIHLLTADCPACGG--ILMTDVVWFGGKVR---RA
RKIIDDAAAVLVAGSSLAVGSALRYVRQAAK-HKPVAIINRGK-RGDKFANVRLSAGTSTALPQLAAQLLRN-------
>tr|A0A0A0BSJ1|A0A0A0BSJ1_9CELL NAD-dependent protein deacetylase OS=Cellulomonas carbonis T26 GN=cobB PE=3 SV=1
------------------------------------L-RGRRVAVITGAGVSTDSGIPDYRGP----S--PPRRPMTYQQFVSDPRTYWARNHVGWRYV-
-HRTQPNAGHRALARLEHA--VVVGVVTQNVDRLHHLAG-RRVIDLHGTYADVVCL-CGHRVTRDTLARLGADCD-CGG--MLKPEIVYFGESVE---RA
FALVDDADALLVAGSSLAVMSGFRFVRHVAR-GRPVVVVNRGA-RGDALATLRVHAGTSETLTALADALAPA-------
>tr|H1XWV5|H1XWV5_9BACT Silent information regulator protein Sir2 OS=Caldithrix abyssi DSM 13497 GN=Calab_3482 PE=4 SV=1
------------------------------------FLKASQIVVLTGDTLCTEAHDILTQGNNGAL-----NELFTIDQLKNDQQKFWENVKKIRQQL-
-ASCKPNLGHYALVDLEN---DDFTLITTSIDGLHQIAG-KNLIELRGNIRRNICQSCGKRFYH------DPVCPACGN--SARPDVLLNDETIQILKKA
QQAAADAELFITVCLKEVHKDHQALPLIAKA-GAYLVELNKEP-VLTDSMDEFVAGNPAKLLTGLVLLLEKI-------
>tr|A0A0H4JXA2|A0A0H4JXA2_VIBCL Uncharacterized protein OS=Vibrio cholerae GN=EN12_21000 PE=4 SV=1
------------------------------------ISNSDRVLFITGAGISVASGLPTYRGEGGLYT--KIEHLLSAFNMDKRPGVIWDVISPLLKGY-
-ESYKPNIAHTQIAQIQKLV--DSCVFTQQVDNLHQKAG-ENVIDIHGNLSVVYCKNCINVRGIKHGY--KPACSFCKS--DLRPNIVPFNGMLEQLEDF
LREP--VSHVFVIGTSLQFPYMEEPIRGCHKYNAKIIYVEPSD--F----DVLSKMTSSEFFENCLRF-----------
>tr|E8R4Y0|E8R4Y0_ISOPI Silent information regulator protein Sir2 OS=Isosphaera pallida (strain ATCC 43644 / DSM 9630 / IS1B) GN=Isop_1139 PE=4 SV=1
------------------------------------LKEARSVLFITGAGMSADSGLPTYRGT-GLYQAGVPEVALSGGMFQRNPAVTWSVLLELANAA-
-RGKRPHRGHEILAAFENDP-DRIWILTQNVDGFHQRAG--QVIDIHGDLSQLQCAECGWEEHVT-----DPRCPVCNS--PIRPNVVLFGELLARLQTE
LRAG--FDLVVSIGTTSVFPYIAQPMIINAR-GKPTLEINPDF-EVSSIADLRLPLGAARALVELERRLA---------
>tr|L0GQ77|L0GQ77_PSEST NAD-dependent protein deacetylase, SIR2 family OS=Pseudomonas stutzeri RCH2 GN=Psest_3021 PE=4 SV=1
------------------------------------LGAAERLLIITGAGLSADSGLPTYRGL-GLYNDGLPEVALSGPTLQRDPALCWKYLAEIGRAC-
-LAAEPNAGHFAIAALQRR--PGTWVLTQNIDGFHRRAG-ERLIEIHGQLAPLSCMACGKTDVRP--L---PRCQGCAG--VLRPAVVLFEEMLNRLQEQ
SRIG--FDAVLVVGTTASFGYILEPVWQARQ-GGFVGEVNLQP-DISPFADVRLEGRAVDVLSHLIRHISSD-------
>tr|H7EXQ9|H7EXQ9_PSEST Putative uncharacterized protein OS=Pseudomonas stutzeri ATCC 14405 = CCUG 16156 GN=PstZobell_13966 PE=4 SV=1
------------------------------------LTGAERILIITGAGLSADSGLPTYRGL-GLYNDGLPEVVLSGPTLRRDPALCWKYLAEIGRAC-
-LQAEPNAGHFAIAELQRR--PGAWVLTQNIDGFHRRAG-DRLIEIHGQLAPLSCLGCGKVDGRP--L---PRCLICSG--VLRPAVVLFEEMLSALKQQ
VQVG--FDAVLVVGTTASFGYILEPVWRVRQ-GGSVVEVNLQP-EISPLADVLLQERAADVLSQLIRHISSD-------
>tr|F2MYH0|F2MYH0_PSEU6 Uncharacterized protein OS=Pseudomonas stutzeri (strain DSM 4166 / CMT.9.A) GN=PSTAA_1316 PE=4 SV=1
------------------------------------LAAAERLLIITGAGLSADSGLPTYRGL-GLYNDGVPEVALSGPTLQRQPALCWKYLAEIGRAC-
-LRAEPNAGHFAIAEWQRQ--PGTWLLTQNIDGFHRRAG-ERLIEIHGELAPLSCMACGEIDRRP--L---PRCEVCTG--VLRPAVVLFEEMLRRLQEQ
SRIG--FDAVLVVGTTASFGYILEPIWRARQ-GGLVVEVNLQP-DISPLANLSLQGRAADVFSHLLRHISSD-------
>tr|A0A061JJK9|A0A061JJK9_PSEST NAD-dependent deacetylase OS=Pseudomonas stutzeri KOS6 GN=B597_020370 PE=4 SV=1
------------------------------------LAGAERILIITGAGLSADSGLPTYRGL-GLYNDGLAEVALSGPTLRRDPALCWKYLAEIGRAC-
-LQAEPNAGHCAIAELQRR--PGAWVLTQNIDGFHRRAG-QRLIEIHGQLTPLSCMRCGNVDSQS--L---PRCQACDG--VLRPAVVLFEEMLATLQEQ
VRVG--FDAVLVVGTTASFGYILEPIWRVRQ-GGFIAEVNLQP-DVSPLADVRLQGRAADALAQLIRHISCD-------
>tr|W0H8U7|W0H8U7_PSECI NAD-dependent deacetylase OS=Pseudomonas cichorii JBC1 GN=PCH70_38000 PE=4 SV=1
------------------------------------LRHAQRILVITGAGLSADSGLPTYRGV-GLYNDGLPEVALSGPMLRRDPELCWKYIAELGKAC-
-LGGQPNAAHYAISQLQRM--PECWVLTQNVDGYHRAAG-ERLIEIHGQMAPLFCQSCGEEDSH---L---PLCQKCSG--VLRPSVVLFQEMLKTLYEE
MAKG--FDAVLSIGTTASFPYIHEPVLRTRI-GGFTAEINPAP-DHSAQMDVFLQCRAAHVMEKLISHI----------
>tr|A0A085VGL9|A0A085VGL9_PSESX NAD-dependent deacetylase OS=Pseudomonas syringae GN=IV02_03785 PE=4 SV=1
------------------------------------LRHAQRILIITGAGLSADSGLPTYRGV-GLYNDGLPEMALSGPMLRRDPALCWRYIAQLAKAC-
-LGAQPNEAHYAIAQLQRK--PECWVLTQNVDGYHRAAG-ERVIEIHGQLAPVYCQSCAAQDPQ---W---PLCSHCGG--ILRPSVVLFEEMLLTLHQE
MAKG--FDAVLSIGTTASFPYIHEPLFRTRV-GGFTAEINLTP-DQSPQMDAFLQCRAAHVMSELVSHI----------
>tr|A0A0Q5EHW6|A0A0Q5EHW6_9PSED NAD-dependent deacetylase OS=Pseudomonas sp. Leaf127 GN=ASF84_06695 PE=4 SV=1
------------------------------------LRHARRILVITGAGLSADSGLPTYRGV-GLYNDDLPEVALSGPMLRRDPALCWKYIAQLGSAC-
-LGGEPNVAHYAIAQLQRL--PECWVLTQNVDGYHRAAG-ERLIEIHGQMAPLFCQACGAQDPH---L---PLCRVCNG--ILRPPVVLFQEMLQALEQQ
MSLG--FDAVLSIGTTASFPYIQEPVLRARV-GGFTLEINPLA-DHSAAMDVFLKGRAAHVMPELISHI----------
>tr|A0A0M0V1F3|A0A0M0V1F3_9PSED NAD-dependent deacetylase OS=Pseudomonas coronafaciens pv. porri GN=ALO89_01500 PE=4 SV=1
------------------------------------LRHAKRILVITGAGLSADSGLPTYRGV-GLYNDGLLEVALSGPMLRRDPELCWKYIAELGKAC-
-LGGEPNVAHYAIAQLQRI--PECWVLTQNVDGYHRAAG-ERLIEIHGQLSPLFCQSCGAQDSQ---L---PLCSICSG--ILRPPVVLFQEMLRTLHEQ
LAIG--YDAVLSIGTTASFPYIHEPVIRTRV-GGFTAEINPQP-DHSAHMDVFLQCRAAHVMAELISHI----------
>tr|A0A085V8F4|A0A085V8F4_PSESX NAD-dependent deacetylase OS=Pseudomonas syringae GN=IV01_23500 PE=4 SV=1
------------------------------------LRHAQRILIITGAGLSADSGLPTYRGV-GLYNDGVPEMAMSGPMLRRDPALCWKYIAELAKAC-
-LGAQPNAAHYAIAELQRK--PDCWVLTQNVDGFHRAAG-ERLIEIHGQLAPLYCQSCGSEDMN---V---PLCTACSG--VMRPSVVLFQEMLQTLYEE
MAKG--FDAVLSIGTTASFPYIHEPVFRTRV-GGFTAEINLTS-NQSAQMDAFFACRAVHVMEELVSHI----------
>tr|A0A0N8SPG5|A0A0N8SPG5_PSESI NAD-dependent protein deacetylase of SIR2 family OS=Pseudomonas syringae pv. ribicola GN=ALO47_100027 PE=4 SV=1
------------------------------------LRHAKRILIITGAGLSADSGLPTYRGI-GLYNDGLPEVALSGPMLRRDPELCWKYIAQLGKAC-
-LGGQPNSAHYAIAQLQRI--PECWVLTQNVDGYHSAAG-ERLIEIHGQMAPLFCQSCGAEDPQ---L---PLCSICSG--VLRPSVVLFQEMLQTLYEQ
LAIG--YDAVLTIGTTASFPYIHEPVIRTRV-GGFTAEINPEA-DHSAQMDVFLKCRAAHVMEKLISHI----------
>tr|U3HSK3|U3HSK3_PSEST Uncharacterized protein OS=Pseudomonas stutzeri MF28 GN=L686_16900 PE=4 SV=1
------------------------------------LRQAERILFITGAGLSADSGLPTYRGV-GLYNDGLPEAALSGPMLELNPGLCWKYLAEIGRAC-
-LAGKPNAGHLAIAELQNR--PGCWVLTQNVDGYHRAAG-QRLIEIHGTLAPLFCMRCGEESA-E--L---PQCSRCSG--VLRPPVVLFEEMLLRLQSE
LQTG--FDAVVAVGTSASFAYIVEPLLHVRN-GGFTAQIDPSA-ELSLLVDVHIAAAAADVLPHLIRHIFSD-------
>tr|A0A0D9AQX5|A0A0D9AQX5_PSEST NAD-dependent deacetylase OS=Pseudomonas stutzeri GN=UF78_05980 PE=4 SV=1
------------------------------------LRQAERILIVTGAGLSADSGLPTYRGV-GLYNDGLPETALSGPMLGLDPALCWKYLAEIGRAC-
-IAAKPNAGHFAIAELQQR--PGCWVLTQNVDGYHLAAG-QRLIEIHGTFAPLFCMACGQESV-D--L---PRCVDCGG--VLRPPVVLFEEMLSRLHDE
LHKG--FDVVVAVGTSASFAYIVEPFLRVRN-GGFTAQIDPSA-ELSFLVDVHIAEGAADVLSRPVRHIFGD-------
>tr|H2CBQ2|H2CBQ2_9LEPT NAD-dependent deacetylase OS=Leptonema illini DSM 21528 GN=Lepil_3853 PE=4 SV=1
------------------------------------FLEQDNILVITGAGISADSGLPTYRGV-GLYNEGYAEDILSIDMFERRPELTWKYLLELEKSS-
-RGRRPNAAHETLAYLEKK--KRLWVLTQNVDGFHHMAG--KLVEIHGNLHRLSCTVCEHEEERD------PACPQCAG--LIRPQVTLFGEALEVYERE
MNRG--FDCVVVIGTSAVFPYIYGPVVEAAR-GIPTLEINPDR-ELSKIVRHFLPGRAAESMLAIRRIVDEA-------
>tr|D0E8I6|D0E8I6_9BACT NAD-dependent protein deacetylase OS=uncultured bacterium HF130_AEPn_1 GN=ALOHA_HF130_AEPn_1_07c PE=4 SV=1
------------------------------------LARSKRALFITGAGLSADSGLPTYRGV-GLYEEGLPEEILSGRMFAKRPELTWKYIYEIEKAC-
-RGRGPNDGHFFISNLEKH--KEVMVFTQNVDGFHKKAG--DIVDIHGDIHRLICTSCGAQTEVE------PFCP-CSS--MLRPDVVLFGEQLDRFEME
MQRG--FDIVFSIGTSSAFPYIVEPVLRARG-AAFTIEINPMK-VISPYVDLHFKGRAKEVLNALAKCVF---------
>tr|A0A0F6UFP8|A0A0F6UFP8_PSEAI NAD-dependent deacetylase OS=Pseudomonas aeruginosa GN=cobB_1 PE=4 SV=1
------------------------------------LRRAERILVITGAGLSADSGMPTYRGL-GLYNEGLPEAALSGPMLRRDPALCWKYLAELGKAC-
-LAARPNAGHEAIAELQKH--PECWVLTQNIDGFHRQAG-ERLIEIHGELAPLYCQSCGAESG-G--L---PRCAACGG--VLRPPVVLFEEMLETLYRE
LRKG--FDAVLVVGTTASFPYIVEPVLRTQQ-GGFTAEVNPGV-ELSERVDVKMTGRALDIMPQVVSHIYR--------
>tr|N2JN38|N2JN38_9PSED Uncharacterized protein OS=Pseudomonas sp. HPB0071 GN=HMPREF1487_04509 PE=4 SV=1
------------------------------------LESAQRILVITGAGLSADSGLPTYRGL-GLYNEGIPEAALSGTMFRHRPDVCWKYLAELGRAC-
-LSAQPNAGHEAIAELQRR--SECWVLTQNIDGFHRRAG-DRVIEIHGEMGPLFCSACEAGNI-P--V---PRCDRCGG--VLRPPVVLFEEALRTLMQQ
NATG--YDVVLLIGTTASFPYVIEPALQTLN-GGFVAEINPTM-DLSASVTVRLQKRAVDVLSIILSHMSD--------
>tr|M4WZB1|M4WZB1_PSEDE NAD-dependent deacetylase OS=Pseudomonas denitrificans ATCC 13867 GN=H681_18105 PE=4 SV=1
------------------------------------LACAERILVITGAGVSADSGMPTYRGL-GLYNEGLPEAALSGPMLRDNPALCWKYLAELGKAC-
-INARPNAGHEAIAELQRL--PECWVLTQNIDGFHRRAG-ERLIEIHGELAPLYCQSCGQESA-E--L---PRCERCAG--VLRPSVVLFEEMLATLYAQ
LRKG--FDVVLLVGTTASFPYIIEPVMRTRA-GGFTAEVNPGL-DLSSVVEERMQGRALDIMPRLLSHIPR--------
>tr|A0A0G3A393|A0A0G3A393_9DELT NAD-dependent protein deacetylase OS=Archangium gephyra GN=AA314_10009 PE=4 SV=1
------------------------------------LSRARSVLFVTGAGISAESGIPTYRGI-GLYDGGVPEVALSGSMFRRRPELTWKHLHEIERAC-
-RGAKFNRAHEVLALMEGC--ERCWVLTQNVDGFHKAAG--NVIDIHGDVHDLRCTRCDFSERVR------PSCPQCGS--VVRPEVVLFEELLEVMERE
FAQG--FDLVFSIGTSSLFPYITAPVVDAVA-RRPTVEINPGQ-QLSRVVDVQLQMGAVAACEAVWAARERW-------
>tr|S4Y8W9|S4Y8W9_SORCE NAD-dependent deacetylase OS=Sorangium cellulosum So0157-2 GN=SCE1572_43240 PE=4 SV=1
------------------------------------LASARSALFITGAGVSAASGIPTYRGI-GLYSEGLAEDALSGWMFQRRPEVTWKYIHQIERAC-
-RGARFNAAHAAIARIERR--PRCWVLTQNVDGFHRIAG--NVIDIHGDIRRILCTRCTYEARVD------PSCPECAA--VLRPDVVLFGEMLEILRRE
LAQG--FDVVVSIGTSSLFPYITGPVLEAAR-GVPTVEINPEE-TISTAVSVRLPMRAVEALEGILSQIEPS-------
>tr|I3CKQ5|I3CKQ5_9GAMM NAD-dependent protein deacetylase, SIR2 family OS=Beggiatoa alba B18LD GN=BegalDRAFT_3380 PE=4 SV=1
------------------------------------LRDAQRILFITGAGMSADSGLPTYRGI-GLYDDNMPEVALSGDMLMRKPEITWKYLLEIEKSC-
-RGASFNRGHEVIAEIEQA--PETWVLTQNIDGFHRLAG--HVIEIHGRVYDLHCVKCRYQFSVT------PSCPKCSG--LVRPNVVLFGEMLPRLYKV
LEDG--VDLVFTIGTTSVFPYIAQPVLAARS-GIPTVEINPGR-EVSYAVRYKVARGAAAVLDEVWQMAKG--------
>tr|U3H2E2|U3H2E2_PSEAC NAD-dependent deacetylase OS=Pseudomonas alcaligenes OT 69 GN=L682_27665 PE=4 SV=1
------------------------------------LKRAERILVITGAGLSADSGLPTYRGL-GLYNEGIPEEAISGPMLQRDPALCWKYLAQLGSAC-
-LAARPNPGHEAIAQLQRL--PECWVLTQNIDGYHRQAG-ERLIEIHGELSPLFCQSCGAESD-Q--L---PKCTVCGG--ILRPPVVLFEEMLKTLYAQ
LRKG--FDAVLAVGTTASFPYIIEPVMRTRQ-GGFTAEINPAS-DLARSVDVHLKGKALDVLQELLSHISID-------
>tr|H0J8W9|H0J8W9_9PSED NAD-dependent deacetylase OS=Pseudomonas psychrotolerans L19 GN=PPL19_04310 PE=4 SV=1
------------------------------------LQRAGRVLFITGAGLSADSGLPTYRGL-GLYNEGIPEAALSGSMLRQRPALCWRYLAQLGRAC-
-AAARPNAAHQAITDFGVS--PGSWVLTQNIDGFHRQAG-ERLIEIHGQLEPLACMNCAQTVA-D--A---PRCPACGG--ILRPPVVLFEEALIRLQGA
VEEG--FDLVIAVGTTAAFGYIQAPIGRTLA-GGDLIEINPDR-SLSGLATVQIKKRAVDVLPRLLSHIEG--------
>tr|W5IT44|W5IT44_PSEUO NAD-dependent deacetylase OS=Pseudomonas sp. (strain M1) GN=PM1_0208550 PE=4 SV=1
------------------------------------VQVAERILVITGAGLSADSGMPTYRGL-GLYNEGIAEQAISGPMLRRDPALCWKYLAQLGRAC-
-LAAAPNAGHEAIAELQRR--PECWVLTQNIDGFHRRAG-ERLIEIHGELRPLFCQSCGAESD-E--L---PRCAVCGG--VLRPPVVLFEEMLASLYGE
LRKG--FDVVLLVGTTASFPYIVEPVLRTRA-GGFVAEVNPAP-DLSSRVDVKIAGRALDILPQLIGHISR--------
>tr|A0A0F0DT42|A0A0F0DT42_9PSED NAD-dependent deacetylase OS=Pseudomonas sp. 21 GN=UB43_10395 PE=4 SV=1
------------------------------------LARAERILVITGAGLSADSGMPTYRGL-GLYNEGIPEVAISGPMLQKDPALCWKYLAELGRAC-
-LNAQPNAGHDAIAELQRL--PECWVLTQNIDGFHRRAG-ERLIEIHGELAPLYCQSCGLENT-E--L---PKCVRCAG--VLRPPVVLFEEMLETLYAQ
LRKG--FDAVLLVGTTASFPYIIEPVLRTRD-GGFTAEINPGL-DLSSVVDERMVGRALDIMPRLLGHIPR--------
>tr|L8MRL4|L8MRL4_PSEPS NAD-dependent protein deacetylase of SIR2 family OS=Pseudomonas pseudoalcaligenes KF707 GN=ppKF707_2515 PE=4 SV=1
------------------------------------LKAAKRILVITGAGLSADSGLPTYRGL-GLYNEGMPERALSGPMLQRDPALCWKYLAQLGRAC-
-LSARPNAGHRAIARLQAL--PECWVLTQNIDGYHRQAG-ERLIEIHGELAPLFCQSCGAESQ-E--L---PRCDSCGG--ILRPPVVLFEEMLQSLYAE
LRKG--FDAVISVGTTASFPYIIEPVFRTRQ-GGFTAEINPAL-DLSPVVDVHLKGKALDVLEELLSHITGD-------
>tr|S6APG5|S6APG5_PSERE NAD-dependent deacetylase OS=Pseudomonas resinovorans NBRC 106553 GN=cobB PE=4 SV=1
------------------------------------IQAAERILVITGAGLSADSGLPTYRGL-GLYNEGLPEEALSGPMLRRNPALCWKYLAQLGRAC-
-LGARPNAGHEAIAELQRF--PECWVLTQNIDGYHRQAG-DRLIEIHGELSPLFCQSCGAESP-D--L---PKCHECGG--ILRPPVVLFEEMLQSLYAE
LRKG--FDAVISVGTTASFPYIIEPVLRTRQ-GGFTVEINPAL-DLSPVVDVHLRGKALEVLQGLLSHISGD-------
>tr|A0A0D6S2W0|A0A0D6S2W0_9PSED NAD-dependent protein deacetylase of SIR2 family OS=Pseudomonas sp. FeS53a GN=SZ55_4767 PE=4 SV=1
------------------------------------LSRAERILVITGAGLSADSGLPTYRGL-GLYNEGIPEEAISGPMLQRDPALCWKYLALLGRAC-
-LAARPNGGHRAIARLQAL--PQCWVLTQNIDGYHRQAG-ERLIEIHGEMAPLFCQSCGRESD-H--V---PRCDGCGG--ILRPPVVLFGEMLHTLYAQ
LRQG--FDAVLAVGTTAGFPYISEPVLRTRQ-GGFTAEINPAV-DLSPVVDVHLKGRALDVLEELLSHISID-------
>tr|I4MWT1|I4MWT1_9PSED NAD-dependent deacetylase OS=Pseudomonas sp. M47T1 GN=PMM47T1_25458 PE=4 SV=1
------------------------------------LRDARRILVITGAGLCADSGLPTYRGL-GLYNEGLPEQALSGPMLERDPALCWKYLAQLGEAC-
-LAGRPNAAHHAIARLQQA--PECWVLTQNIDGYHRQAG-ERLIEIHGHLASLFCRACGAVRD-D--L---PRCNACDG--VMRPSVVLFEEVLGALYQQ
LALG--FDVVLVIGTTASFPYIHAPIAETRA-GGFAIEINPLR-GLSAGMDVFFESRALEVMPKLLSHIFLD-------
>tr|A0A077LDJ9|A0A077LDJ9_9PSED NAD-dependent deacetylase OS=Pseudomonas sp. StFLB209 GN=PSCI_0386 PE=4 SV=1
------------------------------------LRHAQRILIITGAGLSADSGLPTYRGL-GLYNDGLPEMALSGPMLRRDPALCWKYIAELGKAC-
-LAGEPNIAHYAIAQLQRL--PDCWVLTQNVDGYHRAAG-ERLIEIHGQMTPLFCQACGAEDPQ---L---PLCSHCHG--ILRPPVVLFQEMLPALQAQ
MALG--FDAVLSIGTTASFPYIHEPVLRTRI-GGFTLEINPQA-DHSAGMDIFLQGRAAHVMPELISHI----------
>tr|F6AKD0|F6AKD0_PSEF1 NAD-dependent deacetylase OS=Pseudomonas fulva (strain 12-X) GN=Psefu_1871 PE=4 SV=1
------------------------------------VIDAQRILIITGAGISADSGLPTYRGI-GLYNDGVPEIAMSGDMLRRDPALCWKYLAQLGSAC-
-LGAQPNAAHRAIAELQAL--SECWLLTQNIDGYHRLAG-DRLIEIHGELAPLYCQVCRQTDE-R--L---PLCTECGG--VLRPPVVLFGERLARLYGQ
LRLG--FDLVISVGTSASFPYIAEPVVQARR-GGVTVEVTLSR-EISHLVDFRLEQRALDVFPELLGHITDH-------
>tr|A0A0D0JMR6|A0A0D0JMR6_9PSED NAD-dependent deacetylase OS=Pseudomonas fulva GN=RU08_20750 PE=4 SV=1
------------------------------------IADAQRILIITGAGLSADSGLPTYRGL-GLYNEGVPEVALSGEMLRRDPALCWKYLAQLGTAC-
-LAAQPNAGHKAIADLQAL--PECWVLTQNIDGYHRLAG-QRLIEIHGELAPLHCQQCAGVDE-R--L---PLCGNCGG--VLRPPVTLFGEMLDRLYAQ
LEKG--FDLVISVGTSASFPYIVEPLLRTRQ-GGVTVEVNLSQ-EVSDLVDFRLEERALDVFPELLSHIVTH-------
>tr|U2B506|U2B506_9PSED NAD-dependent deacetylase OS=Pseudomonas sp. EGD-AK9 GN=N878_09160 PE=4 SV=1
------------------------------------IEQAERILVITGAGLSADSGLPTYRGL-GLYNEGLPEAALSGPMLRRDPALCWKYLAELGKAC-
-LGAAPNAGHLAIAELQRR--PGCWVLTQNIDGYHRAAG-ERLIEIHGELAPLYCQSCGAEDS-K--L---PRCRQCGG--VLRPPVVLFEEMLASLYGE
LRKG--FAVVLSVGTSASFPYIVEPVLRTRQ-GGLSVEINPTL-DLSDVVDVRLAGRALDVLPELLGHISSD-------
>tr|A0A0A1YDV6|A0A0A1YDV6_9PSED NAD-dependent deacetylase OS=Pseudomonas taeanensis MS-3 GN=TMS3_0121210 PE=4 SV=1
------------------------------------IAAAERILIITGAGLSADSGLPTYRGL-GLYNEGLPETALSGPMLQRDPALCWKYLAELGKAC-
-LGARANAGHVAIAALQRR--PQCWVLTQNIDGYHRAAG-ERLIEIHGELAPLYCQSCGAEDP-Q--L---PRCQQCGG--ILRPPVVLFEEMLPSLYAE
LAKG--FEVVLSVGTTASFPYIVEPILRTRQ-GGLTVEINPTR-DLSDAVSLHLQGRALDVLPELLGHI----------
>tr|C1DPQ2|C1DPQ2_AZOVD NAD-dependent deacetylase, Sir2-family protein OS=Azotobacter vinelandii (strain DJ / ATCC BAA-1303) GN=Avin_33190 PE=4 SV=1
------------------------------------LSRAERILVISGAGLSADSGLPTYRGL-GLYNEGLPEAALSADMLRRDPALCWKYLAELGRAC-
-LAARPNAGHEAIAELQRR--PGCWVLTQNIDGYHRAAG-ERLIEIHGELAPLYCQTCGRRSE-E--L---PRCAYCGG--VLRPPVVLFGEELHTLAEQ
LTRG--FDAVLAVGTTASFPYIVEPVLRTWQ-GGFTAEINPQR-DLSDIVDIHAPERASRLLPALLERLSRG-------
>tr|A0A024HDE2|A0A024HDE2_PSEKB NAD-dependent protein deacylase 2 OS=Pseudomonas knackmussii (strain DSM 6978 / LMG 23759 / B13) GN=cobB2 PE=4 SV=1
------------------------------------LQRAERILVITGAGLSADSGMPTYRGL-GLYNEGVPEVAISGPMLRRDPALCWKYLAELGKAC-
-LNAAPNAGHEAIAELQRR--PQCWVLTQNIDGFHRRAG-ERLIEIHGELQPLYCQSCGAESD-E--L---PRCAACGG--VLRPPVVLFEEMLEALYAQ
LRQG--FDLVLLVGTTASFPYIVEPVLRTRA-GGFTVEVNPAS-DLSSVVDVKIEGRALDILPRLISHISR--------
>tr|U2Z743|U2Z743_PSEAC NAD-dependent protein deacylase OS=Pseudomonas alcaligenes NBRC 14159 GN=cobB PE=4 SV=1
------------------------------------IQNAERILIITGAGLSADSGLPTYRGL-GLYNEGLPEAALSGPMLQRDPALCWKYLAQLGEAC-
-LGAAPNAGHAAIAELQRR--PGCWVLTQNIDGYHRAAG-ERLIEIHGELAPLYCQSCGAEDP-E--L---PCCAQCGG--VLRPPVVLFEEMLGRLYDQ
VRQG--FEVVIAVGTTASFPYIVEPVLEARR-KGFTVEVNPQQ-DISRLVDVRLSGRASDVLPELLSHISGH-------
>tr|W8R619|W8R619_PSEST NAD-dependent deacetylase OS=Pseudomonas stutzeri GN=CH92_07660 PE=4 SV=1
------------------------------------LRQAERILIITGAGLSADSGLPTYRGV-GLYNDGLPEAALSGPMLDLDPALCWKYLAEIGRAC-
-MTAKPNVGHLAIAELQRR--PDCWVLTQNVDGYHLAAG-QRLIEIHGTFAPLFCMVCGQEGA-E--L---PRCANCSG--VLRPPVVLFEEMLLRLQAQ
LLEG--FDVVVAVGTSASFAYIVEPLLRVRN-GGFTAQIDPAA-ELSLLVDVHIAEAASDVLPRLVRHIYTD-------
>tr|E6W156|E6W156_DESIS Silent information regulator protein Sir2 OS=Desulfurispirillum indicum (strain ATCC BAA-1389 / S5) GN=Selin_1747 PE=4 SV=1
------------------------------------ISESRRILFITGAGISADSGLPTYRGL-GMYNDGIPEQALAAKMLKIDPSVSWKYLMRIEESC-
-RHATFNRAHEVIALLEQH--PDTWVLTQNIDGFHRQAG--NLVEIHGRYTDLRCMDCDFKQSVE------PRCPQCHE-GILRPGVVLYGETLGTIQHQ
LRLG--FDMVITIGTSNQFPYITEPVLQVKR-GGVTVEINPQP-VLSDVVDHFLPLGAAEAMERIWRAVEPT-------
>tr|A0A098T221|A0A098T221_9PSED NAD-dependent deacetylase OS=Pseudomonas lutea GN=LT42_10235 PE=4 SV=1
------------------------------------LRHATRILIITGAGLSADSGLPTYRGV-GLYNDGLPEMALSGPMLRRDPALCWKYIAQLGSAC-
-LGGRPNAAHYAIAELQRR--PECWVLTQNVDGYHRAAG-ERLIEIHGQLAPLYCQSCGAEDPL---L---PLCACCNG--VLRPPVVLFGEMLLVLQEE
MAKG--FDAVLSIGTTASFPYIHEPMLRARV-GGFAAEINPSP-DHSAHMDAFLRCKALEVMDDIVSHICFD-------
>tr|F4XZY8|F4XZY8_9CYAN NAD-dependent protein deacetylase, SIR2 family OS=Moorea producens 3L GN=LYNGBM3L_58520 PE=4 SV=1
------------------------------------ILKAESILFIVGAGLSADSGLPTYRGV-GLFEEGVPEEAISKNMLQTRPEVTWKYLWQIGAAC-
-HKAKFNRGHEIIAQIESW--PGTWVLTQNIDGFERAAG--NLIQVHGQLSELFCVNCSYRTTAEELL---PKCPACEG--LIRPDIELFGEHHSTFKIL
DNAP--IDIIFLIGTSRDYQYITKPLYKARR-NVPIVEINPAE-VLSEIANYHILSTAADTLDKLWNICEKQ-------
>tr|K9EZB6|K9EZB6_9CYAN NAD-dependent protein deacetylase, SIR2 family OS=Leptolyngbya sp. PCC 7375 GN=Lepto7375DRAFT_0319 PE=4 SV=1
------------------------------------LSQAEQILFITGAGLSADSGLPTYRGV-GLYEEGFPEEALSGSMFQVQPDITWKYLWQIGAAL-
-HNTCHNRGHEVIAEIERH--PNTWVLTQNIDGFHRSAG--NLVEIHGRASELYCIKCDYVTTAQDFL---PICPACQG--IIRPAVVLFGEALRALYQF
QDTA--WDLVFAVGTSGLFPYIAAPLVQAQL-GIPTVEINPGE-MLSSVVEYRIALGAAVALEQIWRLAQH--------
>tr|A0A0C3HYM5|A0A0C3HYM5_9RHOO Sir2 family protein OS=Thauera sp. SWB20 GN=PO78_1685 PE=4 SV=1
------------------------------------LARAQRILFVTGAGISVDSGLPTYRGI-GLYHEGLTEEALSGEMMATRPEIAWRYIAQIEASC-
-RGAKPNAAHRLIAALEQE--ALVCVLTQNVDGLHRAAG--NVIEIHGTVHRLHCMSCGQGRRVE------PECPRCGG--ILRPDVVLFGEALLRLESV
LSQG--MDAVVSIGTTSVFPYIAGPVLWAAR-GTPTVEINPGD-QVSQFVDHRLRMCAAEALPELWWRMHPA-------
>tr|G8QQ28|G8QQ28_DECSP NAD-dependent protein deacetylase, SIR2 family OS=Dechlorosoma suillum (strain ATCC BAA-33 / DSM 13638 / PS) GN=Dsui_2796 PE=4 
------------------------------------LAEARRVLFITGAGISADSGLPTYRGV-GLYEEGFSEEALSGPMLHQHPQITWKYLAQIERTC-
-RDARPNRAHQVIADLERR--TAVTVFTQNIDGLHRQAG--DVIEIHGRLHHLHCTRCSYEVEVD------PACPRCNA--LVRPRVVLFGESLMQLLRT
LDAG--PDMVFSIGTSSLFPYVAEPVLWASE-GITTVEINPGT-PVSPFADHHITQGAAATLEALWQRLR---------
>tr|A0A0K6IRZ3|A0A0K6IRZ3_9PROT NAD-dependent protein deacetylase, SIR2 family OS=Tepidiphilus thermophilus GN=Ga0061068_102179 PE=4 SV=1
------------------------------------LALARRPLFITGAGISAASGLPTYRGT-GLYAEGLPEDVLSGYMLRTRPELTWRELLRMAQRL-
-ARAQVNEAHRAIAALPH-----AVVLTQNVDGLHLEAG--NVIEIHGNLRELHCTVCTYRRPNE------PRCPECGA--VLRPSAVLFGEPLERLDEE
LARG--FDLVFSVGTTSLFPYIAEPVALAAS-GIPTIEINPEP-AVSHLVDYRLRGDAAQILPRIVETARSR-------
>tr|A1KBS0|A1KBS0_AZOSB NAD-dependent deacetylase OS=Azoarcus sp. (strain BH72) GN=npd2 PE=4 SV=1
------------------------------------LADASRILFITGAGISADSGLPTYRGI-GLYHDGLTEEALSGHMMAARPALTWKYIAEIEANC-
-RGAQPNAAHRVIAALERE--PDAWVLTQNVDGLHRAAG--RLIEIHGTVHHLRCTECRHERTVE------PECPACGG--VLRPDIVLFGEMLPRLEHL
IDAG--FDLVVSVGTTSVFPYIAGPVWWARQ-GVPAVEINPGD-EVSHLVRHRLRMPAARAFEELWRRLHPE-------
>tr|N6YRG0|N6YRG0_9RHOO NAD-dependent deacetylase OS=Thauera linaloolentis 47Lol = DSM 12138 GN=C666_16310 PE=4 SV=1
------------------------------------LEQAQRILFITGAGISADSGLPTYRGI-GLYHEGLTEEALSGEMMALRPDISWKYIAEIEANC-
-RGARPNAAHRLIAAFEQE--AMVCVLTQNVDGLHADAG--NLIEMHGTVHRLRCNDCTHARQVA------PECPRCGG--VMRPDIVLFGEQLRRLEHM
LQAG--VDLVVSIGTTSVFPYIAGPVVWAAR-GVPTVEINPGD-EVSRIVRHRLRMTASEAMHELWYRIHPH-------
>tr|Q5P3W1|Q5P3W1_AROAE NAD-dependent deacetylase 2 (Sirtuin/SIR2 like protein) OS=Aromatoleum aromaticum (strain EbN1) GN=npd PE=4 SV=1
------------------------------------IAGAPRILFITGAGISADSGLPTYRGI-GLYHDGLTEEALSGEMMEAHPEVAWKYIAEIEANC-
-RGAAPNIAHRIIAALEHE--PGVWVLTQNVDGLHRAAG--NLIEIHGSVHRLRCTECKHARSVP------PGCPVCGG--VLRPDIVLFGEMLTRLEAL
LDDG--VDLVVSIGTTSVFPYISGPIWWADQ-GVPSVEINPGE-GVSGIVTHRLRLRAAEAMPKLWRRLHPE-------
>tr|S9ZRT0|S9ZRT0_9RHOO NAD-dependent deacetylase OS=Thauera terpenica 58Eu GN=M622_00720 PE=4 SV=1
------------------------------------LAQAQRVLFITGAGVSADSGLPTYRGI-GLYHEGLTEEALSGEMMARRPDISWKYIAEIEGNC-
-RGARPNAAHRLIAAFERE--DLVCVLTQNVDGLHAEAG--QLIEIHGNVHRLRCTDCMQARQVP------PECPRCGG--TLRPDIVLFGEALGRLEHV
LESG--LDLIVSIGTSSVFPYIAGPVMWAAR-GLPTVEVNPGD-AVSRFVEYRLRMGASDALHELWYRTHPR-------
>tr|H0PWX4|H0PWX4_9RHOO NAD-dependent deacetylase OS=Azoarcus sp. KH32C GN=npd PE=4 SV=1
------------------------------------IDDSDRILFITGAGISADSGLPTYRGI-GLYHDGLTEEALSGEMMYRRPDITWKYIAQIEANC-
-RGAQPNIAHRIIAALEHE--PGVWVLTQNVDGLHRDAG--NLIEIHGTVHRLRCIECHHARTVT------PACPSCGG--LIRPDVVLFGEMLARLQAL
LDDG--VDLVVSIGTTSVFPYISGPIWWADQ-GVPSVEINPGE-EVSRLVTHRIRMKAAEAMPELWRRLHPE-------
>tr|A0A0J8T4A5|A0A0J8T4A5_9RHOO NAD-dependent deacetylase OS=Thauera humireducens GN=AC731_13710 PE=4 SV=1
------------------------------------LERSRRILFITGAGISADSGLPTYRGI-GLYHEGLTEEALSGEMMALRPDIAWRYIAEIEANC-
-RGARPNAAHRLIAALEQE--PMVCVLTQNVDGLHADAG--NLIEIHGTVHRLRCNECTHGRKVP------PECPRCGG--FMRPDVVLFGEALRRLEHV
LQGG--IDLVVSIGTTSVFPYIAGPVVWAAR-GVPSVEINPGD-EVSHLVDHRLRMGAAEAMAELWQRIHPH-------
>tr|A0A0K1JC40|A0A0K1JC40_9RHOO NAD-dependent deacetylase OS=Azoarcus sp. CIB GN=AzCIB_4282 PE=4 SV=1
------------------------------------IGDARRILFITGAGISADSGLPTYRGI-GLYHEGLMEEALSGEMMQRRPDISWKYIAQIEANC-
-RGAQPNIAHRIIAALEHE--PGVWVLTQNVDGLHHDAG--HLIEIHGTVHHLRCMDCSHQRSVK------PACPKCGG--VLRPDVVLFGEMLARLETL
IAHG--LDLVVSIGTTSVFPYIAGPVWWARE-GVPSVEINPGD-EVSEIVTHRLRLGAAEAMPELWRRLHPE-------
>tr|N6YLD8|N6YLD8_9RHOO NAD-dependent deacetylase OS=Thauera sp. 27 GN=B447_11072 PE=4 SV=1
------------------------------------LAEAQRVLFITGAGISADSGLPTYRGI-GLYHDGLSEQALSGQMMAARPALTWKYLAEIEASC-
-RGARPNVAHDIIAALERE--GGVWVLTQNVDGFHRLAG--NLIEIHGNLHRLRCTECPHARSLP------PACPVCGG--VMRPDVVLFGEALGRLEAL
VMHG--LDLVVSIGTTSVFPYIAGPVVHAWR-GVPTVEINPGD-EVSAIVTHRLRMRAAEALPELWRRMRPC-------
>tr|A0A084IQ08|A0A084IQ08_9GAMM NAD-dependent deacetylase OS=Salinisphaera hydrothermalis C41B8 GN=C41B8_01642 PE=4 SV=1
------------------------------------LGSASRVLVITGAGMSADSGMPTYRGV-GLYEDGVAEEALSGPMFERDPALTWKYIAQIESAC-
-RGARPNAGHHAIVDLADH--EHLCVVTQNVDGLHRAAG--ELIEMHGNIHRLFCIRCGQSRTVP------PRCGRCNG--LERPAVVLFEEMLSRYQRE
LAGG--FDVVLMIGTTAVFEYIAAPVRAAAS-QGTAIEINPAD-PVTALCDIKCPGPAADVVPAIVQQLETR-------
>tr|U2FMY0|U2FMY0_9GAMM NAD-dependent protein deacylase 2 OS=Salinisphaera shabanensis E1L3A GN=cobB2 PE=4 SV=1
------------------------------------LAAAQRVLVITGAGMSADSGLPTYRGV-GLYDDGISEQALSGDMFKRDPAVSWKYIAEIERAC-
-RGALPNDGHRALAAMASR--ERFCVLTQNVDGFHQSAG--DVIEMHGAIHRLKCTRCHWHATVE------PCCPDCSS--VVRPDVVLFGEMLRQYEQA
LGEG--FDLVMVVGTSAVFPYIAAPVQRAAM-RRATMEINPQR-DISEYCDVCLQATAADTLVALAGAM----------
>tr|A0A0Q0JRS1|A0A0Q0JRS1_PSEA0 NAD-dependent deacetylase OS=Pseudomonas amygdali pv. ulmi GN=ALO41_01076 PE=4 SV=1
------------------------------------LRHAQRILVITGAGLSADSGLPTYRGV-GLYNDGLPEMALSGPMLRRDPELCWKYIAELGRAC-
-LGGEPNIAHYAIAQLQRI--PECWVLTQNVDGYHRAAG-ERLIEIHGQLSPLFCQSCGAEDPQ---L---PLCPACSG--VMRPPVVLFQEMLKTLYEQ
LAKG--YDAVLSIGTTASFPYIHEPVIRTRV-GGFTAEINPQP-DHSAQMDVFLQCRAAHVMCGTHKSHLVR-------
>tr|Q47EY8|Q47EY8_DECAR Silent information regulator protein Sir2 OS=Dechloromonas aromatica (strain RCB) GN=Daro_1847 PE=4 SV=1
------------------------------------LRHARSALFITGAGISVDSGLPTYRGV-GLYDEGLREDALSGEVFSMRPDITWKYLIQIEENC-
-RGAQPNAAHRAIACLERH--DRVMVFTQNVDGLHRAAG--EIVEIHGNLQELMCTACSHEEAAT------PLCPACGA--VLRPKVVLFGEALDRFIEA
FQEG--FDIVFSIGTSSIFPYIVQPVVLAAA-GIPTVEINPAR-KLSDTVDYYLPLGAAEAMSGIVERLGLD-------
>tr|S9QNR4|S9QNR4_9DELT NAD-dependent protein deacetylase of SIR2 family OS=Cystobacter fuscus DSM 2262 GN=D187_004195 PE=4 SV=1
------------------------------------LSRARSVLFITGAGISAESGIPTYRGI-GLYDEGLPEVALSGSMFQRRPELTWQHIHQIERAC-
-RGATFNRAHEILARVEEC--ERCWVLTQNVDGFHRTAG--NVIDIHGDIHELRCTRCSFTERVV------PNCPRCGA--LLRPEVVLFEEMLTRLQQE
LAMG--FDLVFSIGTSSLFPYIDGPVLEAVA-KRPTVEINPGR-DISDVVDVKLRMGAVAACEALWAERDRW-------
>tr|A6G2Q4|A6G2Q4_9DELT NAD-dependent deacetylase OS=Plesiocystis pacifica SIR-1 GN=PPSIR1_31683 PE=4 SV=1
------------------------------------LAPAQSVLFVTGAGISADSGLPTYRGV-GLYDEGLPEVCLSGEMFRTRPAVTWKYMHEIGRAC-
-RGAEPNAAHRAIAALEAE--ERVWVLTQNVDGLHTAAG--KLIAIHGDAHELACTRCSWSTRVT-----DPRCPRCGA--IVRPAVILFGEMLRTLYAQ
LDLG--FDAVVSVGTTAVFPYIAAPIQLARA-GKATIEINPGT-EISSLVDVHLRLGAAEAMTQLRAAMTP--------
>tr|L0DDV2|L0DDV2_SINAD NAD-dependent protein deacetylase, SIR2 family OS=Singulisphaera acidiphila (strain ATCC BAA-1392 / DSM 18658 / VKM B-2454 / MO
------------------------------------LRPDRRLLFITGAGLSADSGLPTYRGV-GLYGHGDAEEVLSGSMMCRNPEVTWEYLIELERTC-
-RGAAPNRAHEVIAAMEDG--AAVWTLTQNVDGLHRRAG--QVIDIHGDLHVLICTRCDYREEVE------PLCPRCDA--IVRPDVVLFGEELELLERE
LGRG--FDLVISVGTSSVFPYIASPVFRAHR-GVPTVEINPGF-EVSEVVDHRMTAGAALVLGTLWDRYLAR-------
>tr|E1VJ89|E1VJ89_9GAMM NAD-dependent deacetylase 2 OS=gamma proteobacterium HdN1 GN=npd PE=4 SV=1
------------------------------------VQNARRILFITGAGISADSGLPTYRGI-GLYNDNVSETALSGATFAKDPLLTWKYLIQVESAC-
-RGAGHNIGHRIISEFERF--PESWVLTQNIDGLHRSAG--QLIEIHGNVTRLHCTSCRFSEIVP------PICPRCFG--IMRPGVVLFGESLLALQTQ
LSLG--FDLIFSIGTTSVFPYIAQPVLDAHY-GAKTVEINPGV-EVSDAVDYKLTLRAAEALPAIWAAMGKT-------
>tr|A0A0N9M1R6|A0A0N9M1R6_9GAMM NAD-dependent deacetylase OS=Beggiatoa leptomitiformis GN=AL038_06750 PE=4 SV=1
------------------------------------LKQAQRILFITGAGMSADSGLPTYRGI-GLYDDNMPEVALSGDMLLRKPEITWKYLLEIEKSC-
-RGASFNRGHAVIAEIERA--PETWVLTQNIDGFHRLAG--QVIEIHGRVYDLHCIKCMHKLIVT------PSCPKCGG--LIRPDVVLFGEMLSRLYQI
LENG--IDLVFSIGTTSVFPYIAQPVLAARS-GIPTVEINPGR-EVSHAVRYKIARGAADTLDEIWRAISP--------
>tr|W6LXF4|W6LXF4_9GAMM NAD-dependent deacetylase 2 OS=Candidatus Contendobacter odensis Run_B_J11 GN=cobB PE=4 SV=1
------------------------------------MRRARRLLFITGAGISADSGLPTYRGI-GLYNDQFPETALSGSMLEANPAITWKYLHQIEYSC-
-RGARFNDAHTIIAEWQD---FEVCVLTQNIDGFHRDAG--NLIEIHGDIHDLLCTRCDYAATVP------PSCPRCHA--PVRPRVVLFGEVLAHLYAE
LDQG--FDLVFSIGTTSVFPYIAGPVAQASQ-GIPTVEINPGE-HVSRFVDYKLTSGAAVSLRAIRQALD---------
>tr|W6MAN8|W6MAN8_9GAMM NAD-dependent deacetylase 2 OS=Candidatus Competibacter denitrificans Run_A_D11 GN=cobB PE=4 SV=1
------------------------------------MRRARRLLFITGAGISADSGLPTYRGI-GLYNDSFSETALSGSMLEMRPEITWKYLHQIEHSC-
-RGACFNDAHAIIAELQN---FEVCVLTQNIDGFHRDAG--NLIEIHGDIHDLYCTRCHYAATVP------PSCPHCQA--SVRPRVVLFGEMLPHLYAE
LDKG--FDLVFSVGTTSVFPYIAGPVVQASQ-GTPTVEINPTD-NVTHFVEYKLASGAAASLRAIRQAFEAS-------
>tr|X5E890|X5E890_9CORY NAD-dependent protein deacylase OS=Corynebacterium glyciniphilum AJ 3170 GN=CGLY_02165 PE=3 SV=1
------------------------------------VRDARRIEVFTGAGMSADSGLDTFRDATGLWSNVDAQAMASIDSWSRDPDPMWAWYLWRAAKA-
-RAAVPHDGHRAVAAWQDMP-VTVHVTTQNIDDLHEHAG--DVSHLHGSLFSFRCTICGAPAAE-PAL--RPECRICGN--PVRPGVVWFGEALA---AA
EESMETCDLVVIVGTSGVVYPAAGLPRIAAS-GVPVVEISPDD-DLTPVATWSLRTTAAVGLPRLLR------------
>tr|L1MAH2|L1MAH2_9CORY Putative NAD-dependent deacetylase OS=Corynebacterium durum F0235 GN=HMPREF9997_02333 PE=3 SV=1
------------------------------------ARNARHVEVFTGAGMSAESGLETYRDDTGLWENVDPQAMASISAWVKDPAPMWAWYLWRARLA-
-HNAQPNAGHEALARWASI--SDVHVTTQNIDNLHERAG--EVTHLHGSLFEWRCTICARPYRN-VDL--RPDCPLCGN--PIRPGVVWFGEALR---TA
EEKMTNADLVVIVGTSGIVQPAASLPIIAAE-GTPILEISPAA-ELTRLASVFLRSTAATALPLLIDALGG--------
>tr|C0E1Z0|C0E1Z0_9CORY Transcriptional regulator, Sir2 family OS=Corynebacterium matruchotii ATCC 33806 GN=CORMATOL_00994 PE=3 SV=1
------------------------------------LSEARRVHVFTGAGMSAESGLETYRNDTGLWENVDPQAMASIDAWARDPEPMWAWYLWRAHVA-
-EDAQPNAGHIALAEWEQLC-DSMLVTTQNIDNLHERAG--HIAHLHGSLFAWRCSICGRPYRI-MEL--RPECPLCHN--PVRPGVVWFGESLR---LA
EQWMMIADVVVVVGTSGVVYPAAALPRIAYE-GTPIIEISPAA-DLTPLATVSWATTAAQGLPELVAKVQES-------
>tr|D5BAR8|D5BAR8_ZUNPS NAD-dependent histone deacetylase OS=Zunongwangia profunda (strain DSM 18752 / CCTCC AB 206139 / SM-A87) GN=ZPR_2106 PE=3 SV=1
----------------------------------------KNLVVLTGAGISAESGIKTFRDADGLWEGHDVMQVASPMGWEKNQELVLDFYNKRRKQLL
--SVHPNPAHRVLAELES-DFD-VAIITQNIDDLHERAGSTQVLHLHGELLKVRSTFDENVFDWKHDLNIGDFCE-HHY--QLRPHVVWFGEAVPMMEKA
IQKVTEADIIVIIGTSMQVYPAAGLIDFAPQK-TPIYFIDPNPNVKQNKYLTVYAEKAVTGVSKLAEELRKKFI-----
>tr|N1WT62|N1WT62_9FLAO NAD-dependent protein deacetylase, SIR2 family OS=Psychroflexus gondwanensis ACAM 44 GN=pgond44_12447 PE=3 SV=1
----------------------------------------KHISILTGAGISAESGVKTFRDHDGLWEGHDVMQVATPQAFEKNPGFVLDFYNIRRQQLL
--TVQPNLAHQRLVDLET-QFN-VDIITQNVDDLHERAGSSRVTHLHGELMKVRSTFDQDIYDWKDDLNLGDFCE-HHY--QLRPHVVWFGEAVPMIEKA
IDILKQTDVLIIIGTSMQVYPAAGLIDFAPSS-TPIYFIDPNPNISDSTGVHLYAEKATTGVDKLVRKLLA--------
>tr|A0M0C3|A0M0C3_GRAFK NAD-dependent deacetylase OS=Gramella forsetii (strain KT0803) GN=npdA PE=3 SV=1
----------------------------------------KRIVVLTGAGISAESGIKTFRDENGLWEGHDVMEVASPLGWKNNIELVLDFYNQRRKQLL
--QVKPNAAHQALVKLQQ-AYD-VQIITQNIDDLHERAGSSKVTHLHGELLKARSSF---DMDWKKDIKVGDFCE-HNF--QLRPHVVWFGEAVPMFQKA
AEIAETADIVIVIGTSMQVYPAAGLVDFVPRS-SPIYFIDPKPNIS--KNLEIIKKTAVKGVPELIERLLNE-------
>tr|I3C8S2|I3C8S2_9FLAO NAD-dependent protein deacetylase, SIR2 family OS=Joostella marina DSM 19592 GN=JoomaDRAFT_3062 PE=3 SV=1
----------------------------------------KKIVVLTGAGISAESGLKTFRDADGLWEGHDVMEVASPQGWKNNMELVLKFYNDRRKQLL
--EVKPNKAHLAIANLEK-DYK-VTIITQNVDDLHERAGSTNVIHLHGELLKARSTFDEDVFDWTKDINVGDFCE-HHH--QIRPHIVWFGEAVPLIDKA
IEEVSVADIIMIVGTSMQVYPAAGLINYKKRN-TPIYFIDPKPSMSKMEGVEIIAERATVGVPIAVEHLSRI-------
>tr|H2BWW2|H2BWW2_9FLAO NAD-dependent deacetylase OS=Gillisia limnaea DSM 15749 GN=Gilli_3538 PE=3 SV=1
----------------------------------------KHVVVLTGAGISAESGIKTFRDADGLWEGHDIMEVASPQGWERNTKKVLQFYNERRKQLL
--AVNPNAAHLALVKLEK-KYK-VSVVTQNIDDLHERAGSTSVIHLHGELLKVRSTF---DMDWRSDLNPGDFCE-HNF--QLRPHVVWFGEAVPMFSVA
AEITEQADILLIIGTSMQVYPAAALMDFVKQG-TRIYFIDPKPTIS--SDITIINEKAAIGVPKLVDQLLEITN-----
>tr|A0A0Q9Z9V3|A0A0Q9Z9V3_9FLAO NAD-dependent deacetylase OS=Salegentibacter mishustinae GN=APR42_15150 PE=4 SV=1
----------------------------------------KKIVVLTGAGMSSESGIKTFRDADGLWEGHDVMDIASPIGWEKDQKRVLEFYNQRRRQLL
--TVDPNAAHTALAELEK-EFD-VEIITQNIDDLHERAGSTKVTHLHGELLKARSTF---NLDWKQDIKPGDFCE-FNY--QLRPHVVWFGEAVPMFEKA
MEIVAEADILMIIGTSMQVYPAAGLVDFAPQG-IPVYFIDPKPNIQ--GNLHIMAEKASIGVPKLVNELINSA------
>tr|A0A0F0A331|A0A0F0A331_9FLAO NAD-dependent deacetylase OS=Vitellibacter vladivostokensis GN=MB09_06690 PE=3 SV=1
----------------------------------------MKIAVLTGAGVSAESGIKTFRDSDGLWEGHDVMEVASPEGFERNPKVVLDFYNQRRKQLL
--TVKPNAAHFALADLEK-NHD-VTIITQNVDDLHERAGSTNLIHLHGELLKVRSTFDEDILDWKEDLNLGDFCE-NNH--QLRPHIVWFGEMVPMIEVA
ADVVARADAVIIVGTSMQVYPAAGLVQYAKPD-AHIYFVDPKPSISE-KRITVFAEKASIGVPKVVELLK---------
>tr|Q2SQP4|Q2SQP4_HAHCH NAD-dependent protein deacetylases, SIR2 family OS=Hahella chejuensis (strain KCTC 2396) GN=HCH_00109 PE=3 SV=1
----------------------------------------AHIVVLSGAGISAESGLPTFRDVGGLWKQYSVHDLASPGGWERNPQLVLEFYNTRRQQAR
--EAQPNAAHTALAALES-QHR-VTIITQNIDDLHERAGSSNVVHLHGEIMKARSSVDESL--NDQDIALGDLCP-QGK--QMRPHVVWFGEMVPMLESA
ADIVATADVLLVVGTSLQVYPAAGLVDCARPN-CPITVIDPGEDVKV-KGATIIRKTACAGVPEWIASLKL--------
>tr|A0A0R2VA34|A0A0R2VA34_9SPHI NAD-dependent deacetylase OS=Sphingobacteriales bacterium BACL12 MAG-120802-bin5 GN=ABR94_04970 PE=4 SV=1
----------------------------------------MRIVVLTGAGMSAESGIPTFRGAGGLWEGHRVEAVASPEGWAADRELVLQFYNERRRHIK
--KAQPNPGHLLLAEMEK-QYD-ICIITQNIDDLHERAGSSDVIHLHGEIMKSRSSRFEEI---TEDIKIGDCCE-KGY--QLRPHIVWFGEMVPMIPTA
CEVIATADVVAVIGTSMLVYPAAGLVDYAPPG-CPVYVINPEPPEHR-QNWHIIAQPAGTGVATFFKHIADE-------
>tr|N6WWK1|N6WWK1_9ALTE Silent information regulator protein Sir2 OS=Marinobacter nanhaiticus D15-8W GN=J057_17345 PE=3 SV=1
----------------------------------------EHIVVLTGAGMSAESGLATFRDNGGLWEKHDVYDVATPEAFQRDPELVLRFYNDRRRQLK
--DVQPNPAHRALAELEE-KYR-VTIITQNVDDLHERAGSTKVVHLHGKLTEARSSKREDV--GYDAIRMGDTCD-MGS--QMRPNVVWFGEAVPMIETA
ADVVGTADHLLIVGTSLEVYPAAGLVDFVDFD-VPITVIDPGEAN-V-SRATVIRKTASEGVLEWLASLRS--------
>tr|L7WBH5|L7WBH5_NONDD NAD-dependent deacetylase, Sir2 family OS=Nonlabens dokdonensis (strain DSM 17205 / KCTC 12402 / DSW-6) GN=npdA PE=3 SV=1
----------------------------------------KNLVVLTGAGVSAESGIATFRDAGGLWEGHDIMEVASPEGYAANPALVLDFYNKRRAQLK
--DVDPNEAHFCIAGLER-NFH-VDVITQNVDDLHERAGSSNVIHLHGELKKARSSKNSNILEWEDDINLGDLSK-DGS--QLRPHIVWFGEEVPAMEQA
IEIVSKADVLLIVGTSMQVYPAAGLKDFAPSH-APIYFVDPAPSLES-GRLNVIKEKAGKGVQMVADLLSF--------
>tr|A0A0B7HDY8|A0A0B7HDY8_9FLAO NAD-dependent protein deacylase OS=Capnocytophaga cynodegmi GN=cobB PE=3 SV=1
----------------------------------------KKIVALTGAGISAESGIKTFRDSDGLWEGHNVMEVASPEGFAKNPNLVLEFYNQRRRQLK
--EVKPNLAHNILSELQS-DYE-VVIITQNVDDLHERAGSKNIIHLHGELLKSRGVDNDKIFDCFGDIHLGDLSP-SGA--QLRPHIVWFGEDVPMISKA
IQEVESCDILLVIGTSLQVYPAAGLMNYAKYN-TPIYYVDLNPQIQS-ENLIVIKEKASIGIQQIADLLRKNQ------
>tr|J6IRG3|J6IRG3_9FLAO NAD-dependent deacetylase OS=Capnocytophaga sp. CM59 GN=npdA PE=3 SV=1
----------------------------------------KKLVVLTGAGISAESGISTFRDAGGLWEGYDVNEVATPEGFAANPELVLDFYNQRRRQLK
--EVEPNEAHRLLAHLEK-RFH-VVVITQNVDDLHERAGSQHIIHLHGELLKSRGVDDPYTYPCTGDIHIGDKSP-TGA--QLRPHIVWFGEEVPLLDKA
IEEVYTADVLMVIGTSLQVYPAAGLMDYRREG-IPVFYIDPNPSLHS-GDLTVIAQKASTGVAKAIELITP--------
>tr|C2M779|C2M779_CAPGI Transcriptional regulator, Sir2 family OS=Capnocytophaga gingivalis ATCC 33624 GN=CAPGI0001_1105 PE=3 SV=1
----------------------------------------QKLVVLTGAGISAESGISTFRDSGGLWEGHDVNQVATPEGFAADPALVLDFYNQRRRQLS
--QVEPNEAHRLLAHLEK-RYE-VVIITQNVDDLHERAGSHNIIHLHGELLKSRGVDNPNTYPCTGDIHVGDKSP-TGA--QLRPHIVWFGEEVPMLEKA
IAQVYSADILMIIGTSLQVYPAASLIDYVKEG-TPIFYIDPNPSLHS-GDLTVIAQKASTGVAKAIELMTP--------
>tr|F0IDU3|F0IDU3_9FLAO SIR2 family NAD-dependent deacetylase OS=Capnocytophaga sp. oral taxon 338 str. F0234 GN=cobB PE=3 SV=1
----------------------------------------QKVVVLTGAGISAESGISTFRDSGGLWEGYDVNEVATPEGFAANPTLVLDFYNGLRRQLR
--QAVPNEAHRLLAQLEK-RYH-VVIITQNVDDLHERAGSHNIIHLHGELLKSRGVDDPNTFPCPGDIHLGDKSP-SGA--QLRPHIVWFGEEVPMLEKA
IAEVYTADILMIIGTSLQVYPAAGLMDYVKEG-TPIFYIDPHPSLHS-GDLTVIAQKASTGVAKAIELIRTP-------
>tr|A0A0C5WE51|A0A0C5WE51_9FLAO NAD-dependent deacetylase OS=Siansivirga zeaxanthinifaciens CC-SAMT-1 GN=AW14_07565 PE=3 SV=1
----------------------------------------KHLVVLTGAGISAESGIKTFRDADGLWEGHDVMQVATPEGFKNNPALVLNFYNQRRKQLF
--EVEPNKAHLDLAYLEN-DYN-ITIITQNVDDLHERAGSTRVIHLHGELLKVRSTFDETILPWKTDLIIGDICK-KSH--QLRPHIVWFGEEVPMIEKA
VEICETADILAIIGTSMQVYPAAGLMHYVPEN-IPIFFIDPKPASV-KKNLNVIAEPATVGVQQMITLLKNS-------
>tr|S7VTI3|S7VTI3_9FLAO NAD-dependent protein deacetylase of SIR2 family OS=Winogradskyella psychrotolerans RS-3 GN=ADIWIN_1590 PE=3 SV=1
----------------------------------------KHIVVLTGAGMSAESGIKTFRDADGLWEGHDVMEVATPEGFKRNPELVLNFYNERRKQLK
--EVEPNQAHKDLAALEN-NYK-VSIITQNVDDLHERTGSSNVIHLHGELRKIRSSGYENIRTWSEDIHLGDTCE-KGH--QLRPHIVWFGEAVPMIDTA
VEICQQADILVIIGTSMQVYPAAGLLDFAPTQ-TPIYYIDPKPA-I-SGKVTVIVKSATEGMKELLALL----------
>tr|A0A0P0DBX9|A0A0P0DBX9_9FLAO NAD-dependent deacetylase OS=Algibacter sp. HZ22 GN=APS56_15405 PE=4 SV=1
----------------------------------------KHIVVLTGAGISAESGIKTFRDANGLWEGHDVMEVATPQGFLNNPALVLDFYNQRRKQLF
--EVKPNSAHYDLASLET-DYK-VSIITQNVDDLHERAGSSHVIHLHGELLKAKSTFDDTIIEWKTDILLGNMCK-KGY--QLRPHIVWFGEDVPMIEKS
VTICETADILIIIGTSMQVYPAASLIHYVPQN-TPTYFIDPKPN-I-KQHLTVIAEKATIGMKKVISLLK---------
>tr|A0A0D7W2E3|A0A0D7W2E3_9FLAO NAD-dependent deacetylase OS=Tamlana sedimentorum GN=PW52_14655 PE=3 SV=1
----------------------------------------KHIVVLTGAGISAESSIKTFRDADGLWEGHDVMEVASPEGFRANPELVLDFYNQRRRQLL
--TVKPNQAHIDLAELEK-NFK-VSIITQNVDDLHERAGSTNVIHLHGELLKARSTKNINVFECKTDIVLGDLCQ-NGH--QIRPHIVWFGEDVPMIEKA
MEVCQTTDILIIIGTSMQVYPAAGLMHYAPDG-IPVYFIDPKPS-V-NKNLTVIAENATIGVKKVIDHYLV--------
>tr|T2KI04|T2KI04_9FLAO NAD-dependent protein deacetylase, SIR2 family OS=Formosa agariphila KMM 3901 GN=BN863_7750 PE=3 SV=1
----------------------------------------KHIVVLSGAGISAESGLKTFRDSDGLWEGHDVMEVATPEGFAKNPELVLEFYNQRRRQLK
--AVEPNSAHFDLASLEQ-DYK-VTIITQNVDDLHERAGSTRVIHLHGELNKAKSVN-NEILSWPNDINIGDICK-DGY--QIRPHIVWFGEAVPMIDLA
VKECETADILIIIGTSMQVYPAAGLMHYVKDK-TPIYYIDPNPA-H-AKHVKIIRENGTSGMKTVLETLSLK-------
>tr|A0A090WV00|A0A090WV00_9FLAO NAD-dependent protein deacetylase of SIR2 family OS=Jejuia pallidilutea GN=JCM19301_404 PE=3 SV=1
----------------------------------------QHIVVLTGAGMSAESGVKTFRDANGLWEGHDVMEVATPEGFAKNPELVLDFYNQRRQQLF
--EVEPNQAHKDLAKLEE-HFK-VTVVTQNIDDLHERAGSTNVIHLHGELLKVRSTFDANILDWKTDLVLGDVCK-KGY--QLRPHVVWFGEDVPMITKA
MEICETADILLIIGTSMQVYPAAGLIHYTPAN-TPTYFIDPKPN-I-KANLTVIAETATVGMKQLIEKLII--------
>tr|G2EC02|G2EC02_9FLAO Sir2 family protein OS=Bizionia argentinensis JUB59 GN=BZARG_1426 PE=3 SV=1
----------------------------------------KHIVVLSGAGVSAESGIKTFRDADGLWEGHDVMEVASPQGFRMNPELVLGFYNQRRKQLL
--TVKPNQAHIDLATLEK-DYN-VTIITQNVDDLHERAGSKNVIHLHGELLKARSTFNEEVVDCKTDINFGDMCQ-SGY--QMRPHIVWFGEAVPMMDKA
MEICATADILIIIGTSMQVYPAASLMHYVPEN-TPVYFIDPKPA-L-QKNITVVEETATVGVKKVIDNYLS--------
>tr|A0A0D7W2P7|A0A0D7W2P7_9FLAO NAD-dependent deacetylase OS=Tamlana nanhaiensis GN=PK35_05740 PE=3 SV=1
----------------------------------------KHVVVLTGAGMSAESGIKTFRDADGLWEGHDVMEVASPEGFKANPELVLDFYNQRRKQLL
--TVKPNQAHLDLAALEK-EFK-VSIITQNVDDLHERAGSTNVIHLHGELLKARSTGNINVFDCKTDILLGDLCD-SGH--QIRPHIVWFGEDVPMIEKA
MEICETADILMIIGTSMQVYPAAGLMHYAPSG-IPVYFIDPKPS-V-NKNLTVIAENATIGVRKVITEFLK--------
>tr|M7MIY0|M7MIY0_9FLAO NAD-dependent protein deacetylase of SIR2 family OS=Formosa sp. AK20 GN=D778_00435 PE=3 SV=1
----------------------------------------KHLVVLTGAGISAESGIKTFRDADGLWEGHDVMEVATPQGFAKNPELVLNFYNQRRKQLL
--SVKPNEAHIALAALES-TYK-VTIITQNVDDLHERAGSSNIIHLHGELLKARSSKNEQIKTWKTDIQLGDLCQ-QGH--QMRPHIVWFGEAVPMIEKA
IDICETADILVIIGTSMQVYPAASLMDFVPSQ-TPIYYIDPKPA-R-NQKITVIPKSATEGVKNLLDFLKNP-------
>tr|A4C1E8|A4C1E8_9FLAO Uncharacterized protein OS=Polaribacter irgensii 23-P GN=PI23P_11477 PE=3 SV=1
----------------------------------------KKMVILTGAGMSAESGIQTFRDADGLWEGHPVMEVASPEGYAKNPELVLNFYNERRKQLL
--EVLPNKAHFNLVKLEN-KYH-VDIITQNVDDLHERAGSTKVTHLHGELLKVRSSADDRILDWKKELLLGDLCT-KNS--QLRPHIVWFGEFVPMLEKA
AKKVQEADLVVIIGTSMQVYPAASLIDFASLN-TPIYFIDPNPKVSRDPNLCIIKDVASSGTDALLHYLNA--------
>tr|A2U212|A2U212_9FLAO Sir2 family protein OS=Polaribacter sp. MED152 GN=MED152_02315 PE=4 SV=1
----------------------------------------KNVVVLTGAGISADSGIKTFRDADGLWEGHDVMEVASPRGFRNNPELVLDFYNQRRRQLL
--EVEPNKAHLNLKKLEK-YYK-VNIITQNVDDLHERAGSIAITHLHGELLKVRSTKNEAVLNWKKDLNLGDVCK-LGY--QLRPHIVWFGEMVPMLDKA
IEITKRADILVVIGTSMQVYPAASLIEFIGNE-VPIYFIDPKPNINRFNKLTVISDNATNGTDKLLEILKL--------
>tr|F6GFF1|F6GFF1_LACS5 NAD-dependent deacetylase OS=Lacinutrix sp. (strain 5H-3-7-4) GN=Lacal_2029 PE=3 SV=1
----------------------------------------KHLVVLTGAGMSAESGLKTFRDANGLWEGHDVMEVATPEGFLNNPELVLEFYNQRRQQLL
--EVEPNTAHYELARLEE-QFK-VSIITQNVDDLHERAGSNTVIHLHGELLKVRSIITPDVYSWRKPLHLGDKDK-NGH--QLRPHIVWFGEAVPLIETA
ANICSQADILLIIGTSMQVYPAAGLKDYIPAQ-THTYFIDPNPA-V-NNALTVIAKTATEGIKDFIKALNSNH------
>tr|K2QNJ1|K2QNJ1_9FLAO Silent information regulator protein Sir2 OS=Galbibacter marinus GN=I215_03053 PE=3 SV=1
----------------------------------------KKIAVLTGAGISAESGIKTFRDADGLWEGHDVMSVATPEGWQNNPELVLDFYNQRRRQLH
--MVKPNVAHLTLAKLEE-QFE-IDIITQNVDDLHERAGSSSVIHLHGELLKARSCVNPSIFPWKEDIKLGDLCK-YQK--QIRPHIVWFGEEVPLLEKA
AAIVAKADLVMIIGTSMQVYPAAGLIDYKKPG-APIYFIDPKPSICEIADLKIIAEKATVGVPIAVDLLSDI-------
>tr|I0EL93|I0EL93_HELC0 NAD-dependent deacetylase OS=Helicobacter cetorum (strain ATCC BAA-429 / MIT 00-7128) GN=HCW_02135 PE=3 SV=1
----------------------------------------KNLVILSGAGISAESGIKTFRDAGGLWEGHDIMEVASPQGWEKNPQKVLDFYNARRRQLF
--EVSPNDAHKALAKLEK-YYQ-VSIVTQNVDDLHERAGSSNVLHLHGELLSVRSVKNPHV---EKDLHLGDLAE-DKS--QLRPDIVWFGEKVLFLKEA
IYLVKKADILMIIGTSLQVYPAASLFTYAPKN-ALIYYIDPMAKSAR-PKIQCISSSAVSAMQDLMPKLIESA------
>tr|W2UPL0|W2UPL0_9FLAO NAD-dependent protein deacetylase, SIR2 family OS=Zhouia amylolytica AD3 GN=P278_16550 PE=3 SV=1
----------------------------------------KKLVILSGAGISAESGINTFRDENGLWEGHDIMEVASPRGWENNPKLVLDFYNKRRRQLL
--EVTPNNAHIAIARIEN-EFD-VTIVTQNVDDLHERSGSRTVIHLHGELLKARSSFDEDIYDWKEDINIGDFCE-HNS--QLRPHIVWFGEAVPMMQPA
IEKVSEADILMVVGTSMQVYPAASLVHYKKVE-TPIYFIDPKPNISKIPNLEIIADKATIGVPHAISMLSRI-------
>tr|A0A023BMM7|A0A023BMM7_9FLAO NAD-dependent deacetylase OS=Aquimarina atlantica GN=ATO12_10825 PE=3 SV=1
----------------------------------------QNIVVLTGAGISAESGINTFRDANGLWEGHDVMEVASPQGWRNNPELVLDFYNQRRSQLH
--TVTPNKAHLDLVTLEE-KFN-VSIITQNVDDLHERAGSSNVIHLHGELLKVRSQFDEQVLDWKHDLVLGDHCE-HNS--QLRPHIVWFGEAVPMMDQA
IKITERADILMIIGTSMQVYPAAGLIQYAKHQ-TPVYFIDPNPAISPTEHLTVLSEKATTGVAKVVDELLG--------
>tr|A0A0K6IIP4|A0A0K6IIP4_9GAMM NAD-dependent protein deacetylase, SIR2 family OS=Marinomonas fungiae GN=Ga0061065_10335 PE=4 SV=1
----------------------------------------QKIVVFTGAGISVESGIETYRGDTGLWHQHDIRDVCHPEGWHKDPQKVLEFYNQRRKEVA
--KASPNAAHLAIAQLE-SQYD-VTVITQNVDDLHERAGSSKILHLHGEVTKVRSDLPSDL---YDAVNIGQRCE-SGL--QLRPHIVWFAEEPFFMEES
IQLFAEADKILVVGTSLQVQPAASLILFAHSA-QDRYIIDPSPM-TPKKF--HLRGNASDIVPRLVNSWLSL-------
>tr|A3J6Y1|A3J6Y1_9FLAO NAD-dependent deacetylase OS=Flavobacteria bacterium BAL38 GN=FBBAL38_13065 PE=4 SV=1
----------------------------------------HHIVFLTGAGISQESGISTFRDANGLWNNHKIEEVASPEGFEKNPQLVLDFYNARRRQLD
--EVEPNAAHHLIAQLET-KYN-VTVITQNIDDLHERAGSTNVLHLHGELRKSRSSNNSNISVCTQDIKLGDLAS-DGN--QLRPHIVWFGEAVPEIEKA
IAITQSADLFVIVGTSMVVHPAASLLLAVPFD-AQTVYIDTNPDVDEGINLLVIKEKATIGVRMLVEECLPY-------
>tr|A0A098C2K0|A0A098C2K0_9PORP NAD-dependent protein deacylase OS=Porphyromonadaceae bacterium ING2-E5B GN=cobB PE=3 SV=1
----------------------------------------KRLVVLTGAGMSAESGISTFRDSGGLWDKYPVEQVATPEGFRANPELVLNFYNIRRRELL
--SVKPNEGHYGLVDLEK-HFE-VNIITQNIDNLHEQAGSSSVIHLHGELMKSRSTADESV-PEKCEILLGDTCE-KGS--QLRPHIVWFGEMVPMMSVA
EEITRKADIFVIIGTSMNVYPAAGLLHDVKYD-TPVYLIDPKDVNTG-RRIHHIRMGASEGVKELKKILLT--------
>tr|A0A0D6TK98|A0A0D6TK98_9FLAO NAD-dependent deacetylase OS=Flavobacterium sp. 316 GN=SY27_12060 PE=4 SV=1
----------------------------------------KKIAILTGAGISAESGIQTFRDADGLWHNHKVEDVASPEGWRKNREVVLEFYNERRRKLK
--EVEPNQAHHLVKQLEE-YFE-VQIITQNIDDLHERAGSTNILHIHGELNKMCSSLNRKVYDCLDDIKIGDKAE-DES--QLRPDIVWFGEDVPLYPVA
IEMVKQADIFMVIGTSLQVYPAANLLSFIKHD-AQLIIINPDHDG-GGGRAIYVKEKATIGMQKVFDVLVKETK-----
>tr|C6W5A0|C6W5A0_DYAFD Silent information regulator protein Sir2 OS=Dyadobacter fermentans (strain ATCC 700827 / DSM 18053 / NS114) GN=Dfer_1211 PE=3 
----------------------------------------KKLVVLSGAGISAESGISTFRDHNGLWDNYRIEDVATPEAWIRNQELVLDFYNQRRKQAA
--DVKPNAAHYALAELEK-HFD-VTIITQNVDNLHEIAGSTNVIHLHGELFKSRSTKDPRV---GWELKTGDLCE-LGS--QLRPHIVWFGEEVPMMDIA
VDVTEQADMFLVIGTSLAVYPAAGLVHYVPTR-KRIYIVDPAKPDITSN-MVFIQEKATTGMQTLIKKYLLPES-----
>tr|A0A085L3W9|A0A085L3W9_9FLAO NAD-dependent deacetylase OS=Schleiferia thermophila str. Yellowstone GN=AT05_03090 PE=3 SV=1
----------------------------------------MKIVVFTGAGISAEAGLKTFRGSEGLWETYKIEDVATPEAWERNPQLVIDFYNQRRKQVI
--TTQPTEAHYLLADLEK-KYPNMWIITQNIDDLHERAGSKNVIHLHGEIRKVRSSVDPNI--EGWELKIGDTCE-LGS--QLRPHVVWFGEEVPLMELA
YEIALQADVFVVIGTSLQVYPAASLAYMISEN-TDKWLIDPNPSITD---YTIIKANASEGLRMWKKIMKL--------
>tr|A0A0A2Y2P4|A0A0A2Y2P4_9PAST NAD-dependent deacetylase OS=Gallibacterium genomosp. 2 GN=P375_07045 PE=3 SV=1
----------------------------------------PICAVLSGAGISAESGLPTFRAEDGLWAGHRVEEVCTPEALERNPQKVLDFYNERRRNAA
--AAQPNAAHLALVELEQ-KYD-VRIITQNVDDLHERAGSKNVLHLHGELNKAQSSFDPDI---YKDQLITDKDP-NGH--LMRPFIVFFGESVPMLEPA
IDIVANADILLVIGTSLQVYPANGLVHEAKRS-AKIYLIDPNPNIGF-QRVNIITQKATEGVAQVVRELLMTKL-----
>tr|W2CI31|W2CI31_9PORP NAD-dependent protein deacylase OS=Tannerella sp. oral taxon BU063 isolate Cell 1/3 GN=T230_11095 PE=3 SV=1
----------------------------------------KKLVILTGAGMSAESGISTFRDSNGLWENYRVEDVATPEGFARNPQLVLDFYNARRRELL
--RAEPNDGHRGLAALEH-DFD-VRIVTQNVDNLHERAGSSHVIHLHGELMKACSERNPNP-PEHPDMRLGDTAP-DGG--RLRPFIVWFGEPVPMIEEA
IRIVSDCDLFAVIGTSLNVYPAAGLLGYVRRG-QPIFLIDPKEVAVY-RNVEFIRCGASEGVRILTDRLQAFR------
>tr|F0NYJ6|F0NYJ6_WEEVC NAD-dependent deacetylase OS=Weeksella virosa (strain ATCC 43766 / DSM 16922 / JCM 21250 / NBRC 16016 / NCTC 11634 / CL345/78) 
----------------------------------------KNIVVLTGAGISAESGISTFRDSNGLWENHDIMEVASIDGWHRNPALVLEFYNQRRRQLK
--NVMPNAAHEYLAKLEE-KYH-VNIITQNVDNLHEKAGSTQVIHLHGELTKACSEKNKSAVDWWDDIVLGDLAE-DGA--QLRPYIVWFGEAVPMMEKA
IELVLQADLFLVIGTSLQVYPAASLLDFVPNN-CPIYYIDPKADEI-SSKINTIRKTATEGVKCLNL------------
>tr|W8VXH0|W8VXH0_9FLAO NAD-dependent protein deacetylase of SIR2 family OS=Nonlabens marinus S1-08 GN=NMS_1903 PE=3 SV=1
----------------------------------------KKIVVLSGAGVSAESGISTFRDAGGLWEGHDVMEVASPEGWQANPELVLDFYNKRRAQLK
--DVEPNAAHHCIAALER-NYE-VQVITQNVDDLHERAGSSQVLHLHGELRKARSSSNIKIQEWTEDITIHDKCA-AGS--QMRPHIVWFGEEVPAMDEA
IDWIQNADAVIVVGTSLQVYPAAGLMHYAPAA-SPIYLVDPSPTLNS-NGLTVIAENASTGIQKACDMIHADLH-----
>tr|A3XMJ6|A3XMJ6_LEEBM Uncharacterized protein OS=Leeuwenhoekiella blandensis (strain CECT 7118 / CCUG 51940 / MED217) GN=MED217_07481 PE=3 SV=1
----------------------------------------KHIVVLTGAGISAESGLKTFRDANGLWEGHDVMEVASPEGWNKNRALVLDFYSQRRKQLK
--EVSPNPAHEALVKLEE-QFK-VDIITQNVDDLHERAGSSSVIHLHGELLKARSTVDENVLDWKEDINEGDLCA-KNS--QLRPHIVWFGEMVPLLDTA
AALTAKADYILIVGTSMQVYPAAGLINYAKPD-AEVFFIDPKPNIRSQANLKVYAEKASTGVPTVVAQLLNN-------
>tr|A0A098LBC8|A0A098LBC8_9BACT NAD-dependent protein deacetylase of SIR2 family OS=Sporocytophaga myxococcoides GN=MYP_795 PE=3 SV=1
----------------------------------------KKIVVLTGAGVSAESGISTFRDAGGLWEGHDIMEVASPEGWRKNPALVLEFYNLRRKAAL
--DAQPNAGHLGLVTLEE-KYD-VTIVTQNVDNLHEKAGSSKIIHLHGELFKCRSSLNENI---SWELKLGEKCP-HGS--QLRPHIVWFGEMVPMMDKA
MKLAMKADIFIVVGTSLQVYPAAGLLDYVGES-IPVYVIDPNMPAVRRPNLHLIEEKASTGVEKVVEILMA--------
>tr|A0A0Q1HHG0|A0A0Q1HHG0_9FLAO NAD-dependent deacetylase OS=Nonlabens sp. YIK11 GN=AAU57_08000 PE=4 SV=1
----------------------------------------KKIIILSGAGVSAESGIATFRDADGLWEGHDVMEVASPQGFENNPSLVLDFYNQRRAQLH
--TVEPNEAHYCIAALER-NYE-VHVITQNVDDLHERAGSTNVLHLHGELLKARSTSNPSIVDWTDDITVADSCP-EGS--QMRPHIVWFGEEVPAMETA
IELTAQADAVIIVGTSLQVYPAAGLMHYAPQE-TPIYLIDPRPNLKS-GNLTVIEENASTGVRKACDMIHLSLT-----
>tr|A0A090Q2X6|A0A090Q2X6_9FLAO NAD-dependent protein deacetylase of SIR2 family OS=Nonlabens sediminis GN=JCM19294_2045 PE=3 SV=1
----------------------------------------KNLVVLTGAGVSAESGISTFRDAGGLWEGHDIMEVASPQGWERNPELVLDFYNKRRAQLK
--TVEPNEAHHIIAGLER-NFQ-VTVITQNVDDLHERAGSSSVLHLHGELRKVRSTVNPDIAHHEDDLHLGDCCA-AGH--QLRPHIVWFGEDVPAMSKA
IDITSKADLFLVVGTSLQVYPAAGLIDYTPIN-CQHFLVDPNPALSS-NGLTVIEEVASTGMRKIEELLFLHHD-----
>tr|V2TRP4|V2TRP4_9GAMM Uncharacterized protein OS=Acinetobacter nectaris CIP 110549 GN=P256_01544 PE=4 SV=1
----------------------------------------KKLVVLTGAGISAESNISTFRDSNGMWENHNIEDVASIEGWNKNPALVNNFYNLRRQNVR
--KATPNIAHDILAELE-SKYD-VTILTQNVDDLHERAGSTNVLHMHGDILTAISSDPNRI---SDLNHLIDLDS-NGY--SLRPNIVWFGEEVRYLLFA
QEAVKKSDIFLVIGTSLNVFPVASLVKYAQGD---CYNINPDIN-THDGY--NIHQVASLGMLEFNAIHS---------
>tr|R9CTZ7|R9CTZ7_ELIME NAD-dependent protein deacetylase, SIR2 family OS=Elizabethkingia meningoseptica ATCC 13253 = NBRC 12535 GN=L100_05031 PE=3 SV=
----------------------------------------KKLVVLSGAGISAESGIKTFRDSNGLWENHKIEDVASPEGFARNPELVLEFYNLRRRQLH
--EVEPNEAHKILAELQK-DFD-VHIITQNVDDLHERAGSQSVVHLHGELNKVRPVNNEEFISWEGDLNWGDTDE-NGT--QLRPHIVWFGEMVPEMENA
ATIASRADILLVVGTSLQVYPAASLLHYVPSH-CEIFVIDPHLT--QTHQKNFFKTSATEGMKLFREAVNGNKV-----
>tr|A0A0F7NWK4|A0A0F7NWK4_ELIME Uncharacterized protein OS=Elizabethkingia meningoseptica FMS-007 GN=M876_09225 PE=3 SV=1
----------------------------------------KKIVVLSGAGISAESGIKTFRDSNGLWENHKIEDVASPEGFARNPELVLEFYNLRRRQLS
--EVNPNEAHYILAELQK-DFD-VHIITQNVDDLHERAGSENIIHLHGELKKARPVNDEEIIPWEGDLNLRDLDE-NGI--QLRPHIVWFGEMVPEMENA
ATIASTADILLVIGTSLQVYPAASLLHYVPTG-CEIFVIDPHLS--QTNEKNFFKTSATEGMKLFREAIYGR-------
>tr|A0A0C1FEY1|A0A0C1FEY1_9FLAO NAD-dependent deacetylase OS=Chryseobacterium jeonii GN=OA86_00265 PE=3 SV=1
----------------------------------------KKLVVLSGAGISAESGVKTFRDSNGLWENHRIEDVASPEGFERNPEMVLDFYNARRKQLN
--EVEPNEAHLILAELED-YFD-VKIITQNVDDLHERAGSSNIIHLHGELKKARSINSDSIISWEKDLNLGDFNS-EGV--QLRPHIVWFGEMVPEMDQA
VKVAETADIFLVIGTSMQVYPAASLIQYIPDH-CEVFVIDPQLD--NVKAENFFKTSATEGMRKLKDRLLK--------
>tr|A0A0C1CQS5|A0A0C1CQS5_9FLAO NAD-dependent deacetylase OS=Chryseobacterium solincola GN=OA84_08095 PE=3 SV=1
----------------------------------------RKLVVLSGAGISAESGVKTFRDSNGLWEEHRVEDVASPEGFARNPQLVLDFYNARRRQLL
--EVQPNRAHEILAELER-DFE-VNIITQNVDDLHERAGSTHVLHLHGELKKARPVNSNSIIPWEKDLNIGDLSE-NGQ--QLRPHIVWFGEMVPEMEKA
IKLVQQAEIFLVIGTSLNVYPAAGLLYDVSPD-CEIYVIDPEIP--MGGNFHFYQTTATEGMALLQKKLLEL-------
>tr|E4TAW6|E4TAW6_RIEAD Silent information regulator protein sir2 OS=Riemerella anatipestifer (strain ATCC 11845 / DSM 15868 / JCM 9532 / NCTC 11014) G
----------------------------------------KRLVVLSGAGISAESGIKTFRDSNGLWENHRIEDVASPEGFARNPQLVLDFYNLRRRQLA
--EVKPNLAHSILAELEK-YYE-VIIITQNVDDLHERAGSSHIIHLHGELKKARPINSESIINWETDLNLGDNNE-KGV--QLRPHIVWFGEAVPEMEKA
IDIATSADLFLVIGTSLQVYPAASLVHYIPQH-CELFLIDPQIP--EIKKATCFATSATEGMIKLKEILLAEF------
>tr|A0A0J7IZP7|A0A0J7IZP7_9FLAO NAD-dependent deacetylase OS=Chryseobacterium koreense CCUG 49689 GN=ACM44_06600 PE=3 SV=1
----------------------------------------KKLVVLSGAGISAESGVKTFRDADGLWENHRIEDVASPEGFQRNPKLVFDFYNERRRQLK
--SVFPNRAHEILAELEE-YFD-VEIITQNVDDLHERAGSTKVTHLHGELKKARPVNADKEIPWEDDLNLGDLNH-EGI--QLRPHIVWFGEMVPNMDKA
LSIVEKADFFLVIGTSLQVYPAASLIHYVPKT-CDVFAIDPNLE--NVREENFLKTSAIAGMQRLKEILTSKAQ-----
>tr|I3ZXA2|I3ZXA2_ORNRL NAD-dependent protein deacetylase, SIR2 family OS=Ornithobacterium rhinotracheale (strain ATCC 51463 / DSM 15997 / CCUG 23171 /
----------------------------------------PKLVALSGAGISQESGIQTFRASDGLWENHRVEEVATPEGFAVNPELVLNFYNARRRQLS
--EVLPNDAHKFFADLEK-QYD-VEIVTQNVDDLHERAGSSKVLHLHGELKKGRSVYDENIFPFEGDMTLEDRAP-NGD--PVRPHIVWFGEAVPALNDA
IALAEQADVFVVIGTSMQVYPAASLVDFLKPE-CQLFVIDPSEIT-LRHPYTHIQEKACAGVKKLAKKLI---------
>tr|C6X5T5|C6X5T5_FLAB3 NAD-dependent protein deacetylase of SIR2 family OS=Flavobacteriaceae bacterium (strain 3519-10) GN=FIC_01325 PE=3 SV=1
----------------------------------------KKLVVLSGAGSSAESGVQTFRDSDGLWENHRIEDVASPEGFARNPQFVLDFYNARRRQLD
--LVQPNDAHRILAKLQD-VLE-VVIITQNVDDLHEKAGSQNVIHLHGELRKARPVDSLTIRIWNKDLNIGDLAE-DGT--QLRPHIVWFGEMVPEMERA
VETAQTADYFLIVGTSMQVYPAAGLVSYVPES-CEIFGIDPNPD--SSAGATFFNTTATEGMRLFKEKLLERP------
>tr|A0A085BAH2|A0A085BAH2_9FLAO NAD-dependent deacetylase OS=Epilithonimonas sp. FH1 GN=IO90_09230 PE=3 SV=1
----------------------------------------KKLVVLSGAGISAESGIKTFRDSNGLWENHRVQDVASPEGFARNPKLVLDFYNARRKQLK
--DVEPNTAHKLLAELED-FFD-VHIITQNVDDLHERGGSTNIIHLHGELKKARSVDNETILDWEDDIHLGDLHT-DSS--QLRPHIVWFGEMVPEMDNA
IEIASQADLFLVIGTSMQVYPAASVVRYVPSH-CEVFVIDPNLENPNTRNENYFKASATEGMKKLKQILIEKYK-----
>tr|A0A083WT92|A0A083WT92_9FLAO NAD-dependent deacetylase OS=Chryseobacterium antarcticum GN=HY04_14100 PE=3 SV=1
----------------------------------------KKLVVFSGAGISAESGVKTFRDSDGLWENHRVEDVASPEGFEKNPKMVLDFYNARRRQLN
--EIEPNKAHLILAELEK-YFD-VQIITQNVDDLHERAGSTKIIHLHGELKKARPVDSENIVDWEQDLNLGDLNL-EGI--QLRPHIVWFGEMVPEMDKA
MEICSQANIFLVIGTSMSVYPAAGLISYIPEN-CEVFVIDPNLP--NTQGENYFKTSATEGMELFKNTILGRID-----
>tr|A0A0A2G5I7|A0A0A2G5I7_9PORP Uncharacterized protein OS=Porphyromonas gingivicanis GN=HQ36_02495 PE=3 SV=1
----------------------------------------KRIVVLTGAGISAESGISTFRDSDGLWEKYPVQQVASIEGFRENPQLVLDFYTTRRKELL
--QCLPNEAHKTLARLEE-KWH-VDIITQNVDNLHEQAGSSRVLHLHGELMKNCSVANTQT-PDNLELKVGDLAP-DGH--QLRPFIVWFGEAVPMIEPA
IKLVQEADIFVVIGTSLNVYPAASLLQYAPKE-SLIFIIDPKPVPHP-LNIEFISTVATEGTKILEEKLRSLE------
>tr|A0A014G6Q9|A0A014G6Q9_ACIBA Sir2 family protein OS=Acinetobacter baumannii 25977_10 GN=J813_2101 PE=4 SV=1
----------------------------------------TRLVVFSGAGMSAESGISTFRDSNGLWENYDIQQVATPEAWDKDPALVQRFYNERRKNIL
--EAQPNEAHQYIAKLQN-HFD-VQVITQNIDDLHERAGSKNVLHLHGNIRLAKSSGPN-F---GWKLDLHDLCP-NGY--PLRPHVVWFGEAVPAFEEA
IKQVHEADIFIVIGSTLSVYPVAALVHEIPNY-TEAYYIDPQADHSR-PSYKLLNMTATEGMKELFYQLTS--------
>tr|A0A0A6Y3U3|A0A0A6Y3U3_9FLAO NAD-dependent deacetylase OS=Capnocytophaga sp. oral taxon 329 str. F0087 GN=HMPREF9074_07799 PE=3 SV=1
----------------------------------------KKIVVLTGAGISAESGVKTFRDADGLWEGHDVEQVATPYGFQKNPELVLNFYNGLRKQLK
--SVQPNAAHLLLAELQK-DYE-VVVITQNVDDLHERAGSKNIIHLHGELLKMRSADDPNIYDCTGDIKVGDLTP-TGV--QLRPHIVWFGEDVPLIVKA
AEEVESADIVLVIGTSLQVYPAAGLMNCAEDN-VPIYYIDPRPSISS-GRLTVIAEKASTGVAKAIALIKEKEN-----
>tr|L1NY48|L1NY48_9FLAO NAD-dependent deacetylase OS=Capnocytophaga sp. oral taxon 380 str. F0488 GN=HMPREF9078_00863 PE=3 SV=1
----------------------------------------KKIVVLTGAGISAESGVKTFRDADGLWEGHDIEQVATPYGFEKDPELVLNFYNGLRKQVK
--NVQPNPAHLLLAELEK-EYD-VVIITQNVDDLHERAGSHHIIHLHGELLKMRGVDDPYLYDCTDDIKVGDLSP-SGA--QLRPHIVWFGEDVPMIVKA
AEEVETADIVVIVGTSLQVYPAAGLMNCAKKD-TPIYYIDPRPSISS-DKITVIKDVASTGVAKAIELIKELK------
>tr|A0A0B7IKV2|A0A0B7IKV2_9FLAO NAD-dependent protein deacylase OS=Capnocytophaga canimorsus GN=cobB PE=3 SV=1
----------------------------------------KKIVVLTGAGISEESGIRTFRDANGLWEGHDVMEVASPEGFSKNPSLVLEFYNQRRRQLK
--EVKPNKAHQLLVQLEN-EYD-VVIITQNVDDLHERAGSSNVIHLHGELLKSRGIDNDAIFDCQDDILLGDLSP-SGV--QLRPHIVWFGEDVPLITKA
IEQVETADIFLIVGTSLQVYPAAGLIHYTQPK-TPVYYVDPFPQIQS-KQLTVIAQKASSGVQKAIETIKSHII-----
>tr|L1NV55|L1NV55_9FLAO NAD-dependent deacetylase OS=Capnocytophaga sp. oral taxon 332 str. F0381 GN=HMPREF9075_02195 PE=3 SV=1
----------------------------------------KKIVVLTGAGVSAESGVNTFRDAGGLWEGYRVEDVATPQGFENNPELVLNFYNERRQQLS
--TVKPNKAHLLIAELQK-DYE-VVVITQNVDDLHERAESKHIIHLHGELLKMREVDNDMT---NHDIKVGDLGV-NGK--QLRPHIVWFGEDVPMIIRA
VEEVETADIVLVIGTSLQVYPAAGLMHYAPEG-TPIYYIDPHPSIGS-GNITVIAEKASVGVEKVIDLIKERYK-----
>tr|W0EU12|W0EU12_9PORP NAD-dependent protein deacylase OS=Barnesiella viscericola DSM 18177 GN=BARVI_07300 PE=3 SV=1
----------------------------------------KRLVVLTGAGMSVESGLSTFRDSGGLWDRYPVEDVATPEGWERNPALVQGFYNKRRKELL
--TVEPNAGHKGLASLEK-EYD-VTIITQNVDNLHERAGSSHVIHLHGELTKVRSVKDESV-PDQYELAPDATDP-YGD--RLRPHIVWFGEAVPMIEPA
IEITEQADIFVVIGTSLNVYPAAGLLRYVRPQ-IPIYLIDPQEVRVP-NRVHVIQKGASEGVAELIELLHRNA------
>tr|K0X361|K0X361_9PORP Uncharacterized protein OS=Barnesiella intestinihominis YIT 11860 GN=HMPREF9448_02689 PE=3 SV=1
----------------------------------------KKLVVLTGAGMSVESGLSTFRDSGGLWDRYPVEDVATPEGWERNPALVQEFYNKRRKELL
--TVEPNKGHFGLATLEK-DYD-VTVITQNVDNLHERAGSTHVIHLHGELTKVRSTKNENI-PDHYEIKADETDR-YGD--QLRPHIVWFGEAVPMIEPA
IEITEEADIFVVIGTSLNVYPAAGLLRYVRPQ-VPIYLIDPKEVKVP-DRVRVIQKGASEGVAELIALLRR--------
>tr|R5I9C0|R5I9C0_9PORP Uncharacterized protein OS=Tannerella sp. CAG:118 GN=BN472_01675 PE=3 SV=1
----------------------------------------KKIVVLTGAGMSAESGLSTFRSSDGLWEQHRVEDVATPEGWFRNPGLVLNFYNMLRKTLI
--SSQPNGGHLGLVDLEK-NFD-VYIITQNVDNLHERAGSHNVLHLHGELMKVRSEKDENV-PEHPEIHLGDVAD-DGA--QLRPYIVWFGEAVPMIEPA
IEWVKAADIFVVIGTSLNVYPAAGLLHYVHRG-TPVYLIDPNEVKDP-GNTRVIRKGATEGVIELKKLLLHS-------
>tr|A0A060R813|A0A060R813_9BACT NAD-dependent protein deacetylase of SIR2 family OS=Mucinivorans hirudinis GN=BN938_1418 PE=4 SV=1
----------------------------------------KNIVIFTGAGVSAESGIATFRDSDGLWANYSIEDVCTPQALARNRGGVIDFYNMRRREVL
--SKKPNDAHLALKRLEN-HFH-TTIVTQNVDDLHERAGSHNVIHLHGEIGKLCSSRDTST--EGWEQRLDERHA-DGS--LLRPFIVFFGEQVPMLEEA
IDIVQKADIFVVIGTSLQVYPAASLLCYLREA-VPVYVVDPKAPPLS-NNIVVIRQTAAKGVPELVNGLIEGSL-----
>tr|A0A0A1S0L0|A0A0A1S0L0_9FLAO NAD-dependent protein deacylase OS=Chryseobacterium oranimense G311 GN=cobB PE=3 SV=1
----------------------------------------KKLTILSGAGISAESGIKTFRDGDGLWENHNITDVASPEGWRKDRELVLEFYNQRRRQLH
--EVRPNEAHKLLAELEK-HFD-VQIITQNIDDLHERAGSTNILHIHGELFKSCSCNNKNI---KEDIRIGDMAE-DGA--QLRPFIVWFGEDVPLYKEA
QEKVKEADILVVIGTSLQVYPAAGLIHEIKDD-CLLVVINPNETGFG-GKAVVMKESATRGMQLLFDKLIDLA------
>tr|A0A0Q5ZW34|A0A0Q5ZW34_9FLAO NAD-dependent deacylase OS=Chryseobacterium sp. Leaf404 GN=ASG31_03040 PE=4 SV=1
----------------------------------------KKLTILSGAGISAESGIKTFRDGDGLWENHSITDVASPEGWRKDRALVLDFYNQRRRQLH
--EVEPNEAHKLLAELEK-HFD-VQIITQNIDDLHERAGSTNITHLHGELFKSCSCSNKNI---KNDINIGDKAE-DGA--QLRPFIVWFGEEVPMMEKA
TQLAQEADIFLVIGTSLQVYPAAGLVHEIKDD-CQLIVINPNETGFG-GQAVVMKETATQGMKILFEKLVDLA------
>tr|A0A085ZXY0|A0A085ZXY0_9FLAO NAD-dependent deacetylase OS=Chryseobacterium luteum GN=IX38_01925 PE=3 SV=1
----------------------------------------KKLTILSGAGISAESGIKTFRDGDGLWENHSITDVASPEGWRKNRELVLEFYNQRRRQLH
--EVQPNEAHQLLAELEK-YFD-VQIITQNIDDLHERAGSTNILHIHGELFKSCSCSNKKI---KGDIRIGDKAE-DGA--QLRPFIVWFGEDVPLMKEA
TKKAKEADIFLVIGTSLQVYPAAGLLHDIKGD-CLLIVINPNETGFG-GQAIVMKESATRGMQLLFDKLVNLA------
>tr|A0A0J7IV90|A0A0J7IV90_9FLAO NAD-dependent deacetylase OS=Chryseobacterium sp. FH2 GN=ACM39_01390 PE=3 SV=1
----------------------------------------KKLTILSGAGISAESGIKTFRDGGGLWENHNVTDVASPEGWRKDKALVLEFYNQRRRQLH
--EVVPNDAHKLIADLEK-YFD-VQVITQNIDDLHERAGSTNILHIHGELFKSCSCNNKSI---KEDINIGDKAE-DGG--QLRPFIVWFGEDVPLMKEA
IEKTKESDIFLVIGTSLQVYPAAGLLHYIKDD-CHLVVINPNETGFG-GQAVVIKETATQGMKLLFDKLVNLA------
>tr|A0A0Q4FC91|A0A0Q4FC91_9FLAO NAD-dependent deacylase OS=Chryseobacterium sp. Leaf201 GN=ASE55_00095 PE=4 SV=1
----------------------------------------KKLTILTGAGISAESGIQTFRDGNGLWENHNVTDVASPEGWRKDRALVLEFYNQRRRQLH
--EVEPNDAHRLLAELEK-YFE-VHIITQNIDDLHERAGSSNILHLHGELFKSCSCNNKNI---KEDIKIGEKAE-DGA--QLRPFIVWFGEEVPLMKEA
AKQAKEADIFMVIGTSLQVYPAAGLIHDIKDD-CLLIVINPNETGFG-GQAVVMKETATKGMKLLFDKLVNLA------
>tr|A0A0N1DUH1|A0A0N1DUH1_9FLAO NAD-dependent deacetylase OS=Chryseobacterium sp. ERMR1:04 GN=AMQ68_20900 PE=3 SV=1
----------------------------------------KKLTILSGAGISAESGIKTFRDGDGLWENHSITDVASPEGWRKDRELVLEFYNQRRRQIH
--EVEPNDAHKIIADLEK-YFE-VEIITQNIDDLHERAGSTNILHIHGELLKSCSCNNKGI---KKDIKIGDKAE-DGA--QLRPFIVWFGEDVPLMKEA
TEKAKQADIFLVIGTSLQVYPAAGLIHEIKDD-CLLIVINPNETGFG-GQAVVMKETATRGMKLLFDKLVNLA------
>tr|A0A0J8XY46|A0A0J8XY46_9GAMM Uncharacterized protein OS=Photobacterium swingsii GN=AB733_11950 PE=4 SV=1
----------------------------------------RKIVVFTGAGISAESGLSTFRDSDGLWENYSVHEIATKGAFEHNPELVLNFYNQRKIAAA
--KALPNKAHIALAELE-AVYD-VIIITQNVDDLHEKAGSSKVIHLHGQLNRAQSSLDSTT---DKPIYIGQHCE-LNS--QLRPNVVWFGEPVMQLEEA
RNYIKSADKVLAIGSSLTVQPAAGLLKKAPYK-AEKKLVSLDIKGRVFGY--FIRGKAASIVPVICKNWQAL-------
>tr|A0A0A7KDL0|A0A0A7KDL0_9FLAO NAD-dependent deacetylase OS=Cellulophaga baltica 18 GN=M666_18015 PE=3 SV=1
----------------------------------------KKIVVLTGAGISAESGIQTFRDADGLWEGYDVMEVASPQGFEKNPKLVLDFYNQRRKQLL
--KVAPNEAHLALKNLEE-YFE-TTIITQNIDDLHERAGSKAIIHLHGELLKVRSTKISRGLDWKKDLKIGDKCI-NGH--QLRPHIVWFGEAVPLLDRA
IEITQEADILIIIGTSMQVYPAASLVNFIKDD-TPIYFVDPRPNIS-FNNLTIIEKTALEGIPELVTQLIKTN------
>tr|A3UBG4|A3UBG4_CROAH Uncharacterized protein OS=Croceibacter atlanticus (strain ATCC BAA-628 / HTCC2559 / KCTC 12090) GN=CA2559_08031 PE=3 SV=1
----------------------------------------KTIVVLTGAGMSAESGLKTFRDADGLWEGHDVMEVATPQAFERNPELVLEFYNQRRKQLK
--EVSPNEGHIGLAKLEE-HFI-VHIITQNVDNLHERAGSSNVIHLHGELNKVRSTFDENVLDWTTDLNLGDFCE-HNH--QLRPHIVWFGEAVPMLDHA
ISITEQADILIIIGTSMQVYPAASLINFVHEE-TPIYFIDPKPNVKASKRLTIIEDTASKGVKKVTDKLLRKD------
>tr|E6X6A9|E6X6A9_CELAD NAD-dependent deacetylase OS=Cellulophaga algicola (strain DSM 14237 / IC166 / ACAM 630) GN=Celal_0051 PE=3 SV=1
----------------------------------------KKIVVLTGAGISAESGIQTFRDADGLWEGYDVMEVASPQGFINNPKLVLDFYNQRRKQLL
--NVLPNNAHYALTALEK-HFE-TTIITQNIDDLHERAGSSTVIHLHGELLKARSTKTSRGIDWKKDMKLGDKCI-NGH--QLRPHIVWFGEAVPLLDKA
IEITQDAAILIIIGTSMQVYPAASLVNFVKNE-TPIYFIDPRPNIT-FNNLNIIEKTAVEGLPELVAQLIKTY------
>tr|A0A0C5VSZ1|A0A0C5VSZ1_9GAMM NAD-dependent protein deacetylase, SIR2 family OS=Gynuella sunshinyii YC6258 GN=YC6258_04426 PE=3 SV=1
----------------------------------------QKVVVFSGAGISAESGLKTFRDSDGLWENHSIYDVATPDAWLRNPELVLRFYNERRQQLG
--TVQPNPAHLAIAGLEQ-AYD-VFVITQNVDNLHERAGSSIVLHLHGELTKARSTVDESV-S--KAIELGDHCE-LGS--QLRPHIVWFGEIVSGLSEA
AELISQADKIMVVGTSLEVEPAASLIHLAPAH-AEKVVIALNMRNRP-AGFEYYQERAGEAVPKVCQRWLEIS------
>tr|A0A0F9HFG9|A0A0F9HFG9_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_2004930 PE=3 SV=1
----------------------------------------KKIAVLTGAGVSAESGINTFRDAGGLWEGHDVMEVASPEGFARNPALVLDFYNQRRRQLK
--EVFSNRAHFALVELEQ-FFD-VSIITQNVDDLHERAGSSNVIHLHGELLKMRSTHDDNILDCEGDIKLGDLTE-QGH--QLRPHIVWFGEAVPLLEEA
ATKVQLADIVIIIGTSMQVYPAAGLVNFAKPG-IPIYFIDPKPSVSKFDNLTIIPKTAVNGVPVLVSELIAEVK-----
>tr|I3YRZ2|I3YRZ2_AEQSU NAD-dependent protein deacetylase, SIR2 family OS=Aequorivita sublithincola (strain DSM 14238 / LMG 21431 / ACAM 643 / 9-3) GN=
----------------------------------------MKIAVLTGAGVSAESGIKTFRDSNGLWEDHDVMEVASPEGFARNPALVLDFYNQRRKELL
--TVQPNAAHFALAELEK-LYD-VTIITQNVDDLHERAGSTNVIHLHGELLKARSTFDEDIFDRKKDLNLGDFCE-HNH--QLRPHIVWFGEMVPMIEVA
AEIVEKADVVIIVGTSMQVYPAAGLMQYAKEN-AHIYFVDPKPSISK-KRITVFAENASTGIPKVVELLK---------
>tr|A6ETC3|A6ETC3_9BACT NAD-dependent deacetylase OS=unidentified eubacterium SCB49 GN=SCB49_11954 PE=3 SV=1
----------------------------------------MNITILTGAGISAESGIKTFRDANGLWEGHDVMEVATPEGFAKNPALVLDFYNQRRRQLL
--EVKPNAAHLALAQLQE-QHN-VYVITQNVDDLHERAGSKNVLHLHGELLKIRSSGNSKIKYWDKDIQVGDLCE-KGH--QWRPHIVWFGEEVPALDKA
ISIVEKADVVIIVGTSMQVYPAAGLMQYAPQH-ASLYFVDPKPSLSS-SKLTVVAEKASTGVLKVVEMINN--------
>tr|A0A099Y3C3|A0A099Y3C3_9FLAO NAD-dependent protein deacetylase of SIR2 family OS=Polaribacter sp. Hel1_85 GN=PHEL85_0367 PE=3 SV=1
----------------------------------------KKIVVLTGAGISAESGIQTFRDANGLWEGHDVMEVASPEGFAANPELVLDFYNQRRKQLL
--EVVPNKAHYNLSKLEK-YFD-VEIVTQNVDDLHERSGSSKITHLHGELLKVRSSADENILDWKKDLILGDLCI-KNS--QLRPHIVWFGEMVPMLDLA
IEITRKADLLIIIGTSMQVYPAASLIDFVKPN-TPIYFIDPKPSVSEFNNLTIIKDIASSGTDKLLELLS---------
>tr|A0A084JVP9|A0A084JVP9_9FLAO NAD-dependent deacetylase OS=Nonlabens ulvanivorans GN=IL45_12965 PE=3 SV=1
----------------------------------------KNLVVLTGAGVSAESGISTFRDSGGLWEGHDVMKVASPQGFAANPELVLNFYNLRRAQLK
--EVEPNLAHHCIAGMER-NFN-VHVITQNVDDLHERAGSSNIIHLHGELRKVRSSKNYHQLHWKDDLHLGDLCD-AGS--QLRPHIVWFGEEVPAMEQA
IEITAKADVLLIVGTSLQVYPAAGLKDYAPDH-CPIYFVDPHPSLES-GRLKVFAENASTGVQKVADLLNMEF------
>tr|A0A0F9VEZ0|A0A0F9VEZ0_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_0148610 PE=3 SV=1
----------------------------------------KNIVVLTGAGISAESGLKTFRDADGLWEGHDVMEVATPEGFQNNPELVLEFYNQRRRQLL
--TVHPNEAHKALVALEK-EYN-VHIITQNVDDLHERAGSSNVIHLHGELLKAKSTDKTEIFECQKDIVLGDTCK-NGF--QIRPHIVWFGEAVPLLDDA
ISITEKADILIIIGTSMQVYPAASLIDFVDLN-TPIYFIDPKPAIKNKNKITVIAENAVEGVPTLVASLIDK-------
>tr|A9DYA6|A9DYA6_9FLAO NAD-dependent deacetylase OS=Kordia algicida OT-1 GN=KAOT1_08058 PE=3 SV=1
----------------------------------------KKIVVLTGAGISAESGIKTFRDADGLWEGHDVMEVASPDGFEKNPALVLDFYNQRRRQLK
--EVAPNKGHLSLVDLEK-HYN-VVIITQNVDNLHERAGSSHIIHLHGELSKSRSTKAPYVYDCSDDIVLGNLCE-NGA--QLRPHIVWFGEAVPMIETA
VAECVQADILLIIGTSMQVYPAASLIDFVPKN-TKIYFIDPNPAVPQYENLTVIAENASVGVPKVVNELIK--------
>tr|I0W9G6|I0W9G6_9FLAO NAD-dependent protein deacetylase OS=Imtechella halotolerans K1 GN=W5A_10814 PE=3 SV=1
----------------------------------------KKIAVLSGAGISAESGIKTFRDADGLWEGHDIMEVASPEGFARNPELVLDFYNQRRKQLL
--TVAPNAGHKALVSLEE-LYE-VSIITQNVDDLHERAGSSHIIHLHGELLKARSTRNEHIYHWTKDIVLGDRCQ-ENH--QLRPHIVWFGEAVPMITPA
SKIVSEADIVIIVGTSMQVYPAAGLIEYSTKG-TPIYFIDPRPALQSSKNLTVIQAPATEGLPVLVSQLLGN-------
>tr|A0A0A2MRR8|A0A0A2MRR8_9FLAO NAD-dependent deacetylase OS=Flavobacterium subsaxonicum WB 4.1-42 = DSM 21790 GN=Q766_02685 PE=3 SV=1
----------------------------------------KKVVVLSGAGISAESGISTFRDAGGLWEGHDVMEVASPEGWRNNPALVLDFYNKRRKQLF
--EVQPNRAHFTVAELEA-DFE-VTVITQNVDDLHERAGSTNVLHLHGELLKARSVYNTLIIDFTGDINLGDLHT-DGH--QLRPHIVWFGEAVPAIELA
VPLVEEADYVIVIGTSLQVYPAAGLLDFAKPD-AAVFYIDPKPAGIPHNPLEVFPLLASEGMELVAGRLKADK------
>tr|A0A0M9VGU8|A0A0M9VGU8_9FLAO NAD-dependent deacetylase OS=Flavobacterium akiainvivens GN=AM493_01530 PE=3 SV=1
----------------------------------------KKLVILSGAGISAESGVSTFRDAGGLWEGHDVMEVASPEGFRANPALVLDFYNKRRRQLF
--EVLPNKAHIIAAELEK-DFE-VTIITQNVDDLHERAGSTHVLHLHGELLKARCTVQYDVIDWKEDISLGQLHPTTGK--QLRPHIVWFGEAVPAIEEA
VGIVEQADYVVVIGTSLQVYPAAGLMDFAKPS-AKIFYVDPKPVSIPRNELEVLAMKASEGIEVVRQRLNQGL------
>tr|Q11SL1|Q11SL1_CYTH3 NAD-dependent deacetylase OS=Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469) GN=npdA PE=3 SV=1
----------------------------------------KNVVVLTGAGISAESGINTFRDSGGLWEGHDVMEVASPEGWRKNPELVLEFYNIRRKDAL
--KAQPNEAHLALVELNK-HFP-VKIITQNVDDLHERAGSTDVLHLHGKLFESRSTANHRI---GWELKPGDRCT-RGS--QLRPNIVWFGEAVPLMDDA
VKLTAKADVFIVIGTSLQVYPAASLVDYAGPD-TEVIVIDPNMPAVKHPLLTLVAEKASIATPRIVRELIEKYK-----
>tr|G0LCY5|G0LCY5_ZOBGA NAD-dependent protein deacetylase OS=Zobellia galactanivorans (strain DSM 12802 / CIP 106680 / NCIMB 13871 / Dsij) GN=npdA PE=3
----------------------------------------KKITILTGAGMSAESGINTFRDAGGLWEGHDVMEVASPEGFAKNPELVLNFYNQRRRQLQ
--QVKPNLAHKALIELEK-LFD-VTIVTQNVDDLHERAGSSNIIHLHGELLKVRSTGNENVLDWTKDLNLGDRCE-QGH--QLRPHIVWFGEAVPLLEQA
AIATQNADILIIIGTSMQVYPAASLIDYAQGH-VPIYFVDPRPSVSEYNHLTVIAKTAVEGVPDLVRDLIESI------
>tr|A0A0D3LA71|A0A0D3LA71_9BACT Silent information regulator protein Sir2 OS=Flammeovirgaceae bacterium 311 GN=D770_01715 PE=3 SV=1
----------------------------------------KKVVVLTGAGISAESGIPTFRDSNGLWEGHNVEDVATPEAWTRNQELVLEFYNQRRKAAR
--DVKPNAGHTALADLEK-HFR-VTIITQNIDNLHEKAGSSKVLHLHGELFKSRSTADESL--TDWELKLGDCCE-KGS--QLRPHVVWFGEAVPMMEPA
IAETAEADIFMVVGTSMQVYPAASLLYYVDDH-IPKYIIDPRLPLVH-PNLFLLEEKASVGVPKVCRELIEKLS-----
>tr|B1ZQZ4|B1ZQZ4_OPITP Silent information regulator protein Sir2 OS=Opitutus terrae (strain DSM 11246 / PB90-1) GN=Oter_0371 PE=3 SV=1
----------------------------------------QHLVVLSGAGMSAESGIPTFRGANGLWENHRIEDVASPAGWARDRATVLRFYNERRKKMW
--ACEPNAGHRGLAALEQ-DFR-VSIVTQNIDNLHERAGSTRVLHLHGELTKSRSTVDPSV--EGWELKLGDRCA-KGS--QLRPHIVWFGEDVPLLGAA
AEIVSSADILVVIGTSLQVYPAASLIDYAPDH-ARVFLIDPHPAPVA-PRVVVIPAGASEGVTRLRQELLP--------
>tr|X5DAB1|X5DAB1_9BACT NAD-dependent deacetylase OS=Draconibacterium orientale GN=FH5T_09295 PE=3 SV=1
----------------------------------------KKLVVLSGAGMSQESGLKTFRDMGGIWEQYDVTEVATPEAWARNPELVLRFYNERRQQLF
--EAQPNGGHCGIAELEK-WFD-VQVVTQNVDNLHERAGSTKVTHLHGELMKARSTIDADI--DNWELKLGDCCE-KGS--QLRPHIVWFGEAVPEIPTA
IDIVQQADILVVIGTSLAVYPAASLVNYVQKG-TPIYVIDPNRPEVY-ENVTYIEKKAEIGVELLKKELEKLK------
>tr|A0A0C1UI55|A0A0C1UI55_9CYAN NAD-dependent deacetylase OS=Hassallia byssoidea VB512170 GN=PI95_34670 PE=3 SV=1
----------------------------------------KKLVVLTGAGISAESGLATFRDSGGLWEGHRVEDVATPEAWNRNPAQVLEFYNQRRKKAL
--DVTPNRGHEILVELED-DFD-VTVITQNVDDLHERAGSSRVLHLHGSLFESRSTADEDV--SGWELKLGDVCE-RGS--QLRPNIVWFGEMVPMIEVA
VRIASDADIFLVVGTSLVVYPAAGLIHYVRRE-VPKFVVDPNLPDIG-PYTTMIAEKAGIGMELVKQKLSEFI------
>tr|H8XTE2|H8XTE2_FLAIG NAD-dependent deacetylase OS=Flavobacterium indicum (strain DSM 17447 / CIP 109464 / GPTSA100-9) GN=npdA PE=3 SV=1
----------------------------------------KKIVVLTGAGMSAESGISTFRDSNGLWENHDIMEVASPQGWKKNPALVLDFYNKRRAQLK
--EVYPNLGHQILAELES-HFD-VQIITQNVDNLHERAGSSHILHLHGELTKVRGEFSEQNIHWEDDVTIGQQNN-QGE--QLRPAIVWFGEAVPKFEEA
VKIAASADIMLIIGTSLQVYPAASLMEYPKAN-VPIIYIDPHPAIDSKKRVHVMAMKASEGLALVKQNLLGKK------
>tr|U2I0D3|U2I0D3_9SPHI Uncharacterized protein OS=Sphingobacterium paucimobilis HER1398 GN=M472_21115 PE=3 SV=1
----------------------------------------NKIVVLTGAGISAESGLQTFRGEDGLWEGYRIEEVATPEAWRNDPIRVQRFYNERRKKCI
--EAQPNAAHRALVQLE-EYAD-VQIVTQNIDDLHERAGSSNILHLHGEIRKSQSSLDSTT---GDELKMGETCT-FGS--QLRPNVVWFGEPVPNMGRA
IRLTKDADFLFVIGTSLQVYPAANLVYEIPRG-CNLVVVDPSIPHIENGNIKIVKEKAAIALPAMVSHFAKHHT-----
>tr|A0A0B8SZ60|A0A0B8SZ60_9SPHI NAD-dependent deacetylase OS=Sphingobacterium sp. ACCC 05744 GN=DI53_3364 PE=3 SV=1
----------------------------------------KNLVVFTGAGISAESGLKTFRGSGGLWEGYNIEEVATPDGWKKDVKKVLEFYNTRRQQCI
--AANPNAAHLALRELEN-DFQ-VQIITQNIDDLHERAGSKNVLHLHGEIRKAQSSLNPRV--DTDTISIGDTCE-LGS--QLRPHVVWFGEAVPNLERA
ARLTREADIFVVIGTSLQVYPAANLLYEVRPG-CEVFLIDPNAEALG-SGIKRIAATATEGVAILRKLLTE--------
>tr|N9GUV3|N9GUV3_ACILW Uncharacterized protein OS=Acinetobacter lwoffii NCTC 5866 = CIP 64.10 GN=F925_02268 PE=4 SV=1
----------------------------------------KKLVVFSGAGMSAESGINTFRDSDGLWEQYRIEDVATPQAWARDPQLVQRFYNARRKNIL
--EAEPNTAHLQIAQLQQ-DYD-VHVITQNIDDLHERAGSSKVIHLHGNICLAKNSGPD-F---ETDLDLKHFCT-AGY--PLRPHVVWFGEAVPAYAEA
QNCVQDADIFVVIGTSLQVYPVAGLIHDIPVS-CQAYYIDPRADQQQ-PVFHKITQTATDGVQQLIQLLEK--------
>tr|A0A010IB44|A0A010IB44_ACIBA Sir2 family protein OS=Acinetobacter baumannii 1239920 GN=J579_1842 PE=3 SV=1
----------------------------------------KKLVVFSGAGMSAESGINTFRDSNGLWEQYRIEEVATPEAWSKNPELVQRFYNERRKNIL
--DAEPNAAHQAIASLED-NFN-VEVITQNIDDLHERAGSKRVLHLHGNIRLAKTSGPD-F---GWELDLQHKCR-QDY--PLRPHVVWFGEAVPAYEQA
IKLARQADIFIVIGSTLSVYPVAALVNEIPAH-CEAYYIDPKADHVQ-PEYQLLSMTATEGVRYLTEKLKRL-------
>tr|D0SSY4|D0SSY4_ACILW NAD-dependent deacetylase OS=Acinetobacter lwoffii SH145 GN=npdA PE=3 SV=1
----------------------------------------KKLVAFSGAGMSAESGIHTFRDSDGLWEQYRIEEVATPEAWAKNPELVQRFYNARRKNIL
--EAQPNAAHQLIADLEN-EFD-VHVITQNIDDLHERAGSSKVIHLHGNIRLAKSSGPD-F---GSELDLQHFCK-AGY--PLRPHVVWFGEAVPAYEEA
QDCVQDADIFVVIGTSLQVYPVAGLIHEIPAK-CPAYYIDPKAEQQH-PAFYKIPQNATDGMQTLLGLLKAGN------
>tr|N8WUB9|N8WUB9_9GAMM Uncharacterized protein OS=Acinetobacter sp. NIPH 899 GN=F969_02199 PE=3 SV=1
----------------------------------------KKLVVFSGAGMSAESGINTFRDSDGLWEHYRIEEVATPEAWAKNTELVQRFYNARRKNIL
--EAQPNAAHQLIAELED-DFD-VHVITQNIDDLHERAGSSKVIHLHGNIRLAKTSGPN-F---GTDLDLKHFCK-EGY--PLRPHVVWFGEAVPAYEEA
QDCVRDADIFVVIGTSLQVYPVAGLIHEIPAH-CTAYYIDPKADQQH-PVFHKISQTATEGMKTLLKLLESEI------
>tr|R5Z156|R5Z156_9BACE Uncharacterized protein OS=Bacteroides sp. CAG:144 GN=BN496_00455 PE=3 SV=1
----------------------------------------KRLVVLTGAGMSAESGLAVFRGSNGLWSGYRIEDVATPEGWIRNPQQVLDFYNARRRELL
--TVKPNDGHKGLAALET-DFD-VRIITQNVDNLHEQAGSRHIIHLHGELMKVRSSRYENI-PDHIDTHIGDLCE-KGY--QLRPHIVWFGEAVPLIESA
IEEVEKADIFVVIGTSLNVYPAAGLLRYVRNG-IPVFLIDPNPVNDA-RVTHVIQKGAGEGVKELTKILKAGL------
>tr|F5IYZ9|F5IYZ9_9PORP NAD-dependent deacetylase OS=Dysgonomonas gadei ATCC BAA-286 GN=HMPREF9455_02207 PE=3 SV=1
----------------------------------------KHIVVLSGAGMSAESGISTFRDSGGLWEQHSIEDVATPEGFRRNPQLVLDFYNARRKAAF
--EAKPNKGHIGLAEMEK-EYK-VSIITQNVDSLHERAGSTNVIHLHGELDKVRSTADPSI-PENAEIKVGDKCE-KGS--QLRPHIVWFGEAVPMIEKA
IEVVQTADVLVVIGTSLNVYPAAGLLNYIRRD-TPVYLIDPNEVKV--QDIHFIKKGASEGVEELRKLLK---------
>tr|A0A0A2ENL6|A0A0A2ENL6_9PORP NAD-dependent deacetylase OS=Porphyromonadaceae bacterium COT-184 OH4590 GN=HW49_06860 PE=3 SV=1
----------------------------------------KNLVVLTGAGISAESGISTFRDSGGLWEQYSIEDVATPEAWVKNPQLVTDFYNQRRKQLL
--EVEPNYGHIGLVELEK-YFN-VQIITQNVDNLHERAGSKNIIHLHGELIKVRSERFENI-PENYEIKIGDKCE-KGY--QLRPHIVWFGEAVPMLEQA
VKITEKADILVVIGTSLNVYPAASLVHYTRRD-TPIYIIDPNSVAI--PNWYYIKKGASEGIKDLIEILKA--------
>tr|E4T558|E4T558_PALPW Silent information regulator protein Sir2 OS=Paludibacter propionicigenes (strain DSM 17365 / JCM 13257 / WB4) GN=Palpr_1713 PE
----------------------------------------KKLVVLTGAGMSAESGISTFRDAGGLWEQHRVEDVATPQGWSRNPALVLDFYNQRRKQLL
--ECKPNAGHLALAELEK-SYE-VRIITQNVDNLHEQAGSSHVLHLHGELMKVRSTSPSEV-TDNYETHLGDKCP-KGF--QLRPHIVWFGEAVPEIENA
IRLTEKADILVIIGTSMQVYPAASLINYIKPN-TPVYLIDPHEVNV--SNVTVIKKGASVGMKELSSILINASV-----
>tr|D7JCZ8|D7JCZ8_9BACT NAD-dependent deacetylase (Regulatory protein SIR2-like protein) OS=Bacteroidetes oral taxon 274 str. F0058 GN=HMPREF0156_00614
----------------------------------------KRVVVLTGAGISAESGISTFRDSGGLWEQYRIEDVASPEGWIRDPRLVTDFYNQRRKQLL
--EVSPNYGHKGLVELEK-YFD-VHIITQNVDNLHERAGSKNIIHLHGELTKVRSERFDNV-PDKYEVKIGDKCE-RGY--QLRPHIVWFGEAVPMLGEA
IKLTETADIFVVIGTSLNVYPAASLVHYVPEG-KPIYIIDPNSIAIN-NNWHYIKKVASEGVKELMKIITSTTQ-----
>tr|J0E4K7|J0E4K7_HELPX NAD-dependent deacetylase OS=Helicobacter pylori Hp H-23 GN=cobB PE=3 SV=1
----------------------------------------KNLVILSGAGISAESGIKTFRDAGGLWEGHDIMEVASPYGWKKNPQKVLDFYNQRRRQLF
--EVYPNKAHKALAELEK-HYQ-VNIITQNVDDLHERAGSSRILHLHGELLSVRSEKDPNV---EKDLNLGDLAQ-DKA--QLRPDIVWFGEEVPLLKEA
VSLVKQVHLLIIIGTSLQVYPAASLYTHANKD-ALIYYIDPKAKNAR-PQVQCINENVVHAMQDLMPKLIEMAS-----
>tr|R9AV35|R9AV35_9GAMM NAD-dependent deacetylase OS=Acinetobacter tandoii DSM 14970 = CIP 107469 GN=I593_02708 PE=3 SV=1
----------------------------------------QNLVVFSGAGMSAESGIQTFRDHDGLWENYNIEDVATPEAWARNPQLVQDFYNQRRKHIL
--HAQPNRAHQLIAQLQQ-HYH-LNVITQNIDDLHERAGNDNVLHLHGNIRFAKSSGPH-F---GWELNLTDRCP-LGY--PLRPHVVWFGEAVPAYAEA
QKIVQHADIFIVIGSSLEVYPVAGLIHEIPLH-CKAYYIDPKAHQQT-PPYQLIAQTATEGMQQLFTLLTT--------
>tr|N8THM8|N8THM8_ACIGI Uncharacterized protein OS=Acinetobacter guillouiae CIP 63.46 GN=F981_01546 PE=3 SV=1
----------------------------------------KKIVVFSGAGMSAESGISTFRDSNGLWENYDIQEVATPEAWRRNPALVQRFYNERRQHIL
--NAQPNQAHDIIAQLEQ-HFD-VIVITQNIDDLHERAGSQQVIHLHGNIRLAKSSKPN-F---GWQLDLQHKCP-EGF--PLRPHVVWFGEAVPAYEEA
VQMIRDADIFIVIGSTLTVYPVAGLIHEIPEY-SDAYYIDPQASYER-PQYQCLKMSATEGMQQLFEKLTTH-------
>tr|N9EL25|N9EL25_ACIBZ Uncharacterized protein OS=Acinetobacter bereziniae CIP 70.12 GN=F938_02274 PE=4 SV=1
----------------------------------------KKIVIFSGAGMSAESGIDTFRDRGGLWENYNIQEVATPEAWQRNPELVQRFYNERRKNIL
--EAKPNLAHRIIAELEQ-YFE-VHVITQNIDDLHERAGSQQVIHLHGNIRLAKSSKPH-F---GWKLDLKDQCP-EGY--PLRPHVVWFGEAVPAYEQA
IQTVQDTDIFIVIGSALAVYPVAGLIYEIPQY-CEAYYIDPQASHSR-PVYECLKMNATDGMQQLFEKFTKH-------
>tr|U7UCH3|U7UCH3_9BACT Transcriptional regulator, Sir2 family OS=Prevotella sp. BV3P1 GN=HMPREF1254_1824 PE=4 SV=1
----------------------------------------KKIVFLTGAGMSVESGFKTFRGSDGLWENYPVEQVATHEGWEADPTLVTNFYNMLRKKLY
--MAKPNEGHRLIQQLEE-AYD-VTVITQNVDNLHERAGSSRVIHLHGELAKVCSSREPYI-QENCTVEPGTKAD-DGS--LLRPFIVFFGESVPMISVA
AEYAREADIFVIIGTSLNVYPAAGLVQYTKPN-CPIYLIDPEAVHTS-IRLKHIQKGASEGMKELMKVLDTNQ------
>tr|A0A099BX19|A0A099BX19_9BACT NAD-dependent protein deacylase OS=Prevotella sp. S7 MS 2 GN=HMPREF0671_03975 PE=4 SV=1
----------------------------------------KHIVFLTGAGMSVESGFKTFRGNDGLWENYPVEQIATHEGWEADPTLVTNFYNMLRKKLY
--QAAPNEGHLLIHELEK-RFE-VTVVTQNVDNLHEKAGSSRVIHLHGELSKVCSSRAPYI-EDDCQIKPGTKAE-DGS--LLRPFIVFFGESVPMMEPA
AVAAHQADIFVIIGTSLNVYPAAGLVQYVRPE-VPVYLIDPNPVNAA-G-IVQIAKGASEGMRQLAKVLE---------
>tr|A0A098YUS5|A0A098YUS5_9BACT NAD-dependent protein deacylase OS=Prevotella timonensis S9-PR14 GN=HMPREF9304_00485 PE=4 SV=1
----------------------------------------KKIVFLTGAGMSVESGFKTFRGSDGLWENYPVEQVASHEGWEANPTLVTNFYNMLRKKLY
--DAQPNEGHRLIQQLEE-KYD-VTVITQNVDNLHERAGSSRVVHLHGELTKVCSSREPYI-KENAEVTPGAKAD-DGS--LLRPFIVFFGESVPMISVA
AQYVQQADIFVIIGTSLNVYPAAGLVGYTRPG-CPIYLIDPDHVGTS-IALEHIQKGASEGMKDLLRILD---------
>tr|H1Q4M3|H1Q4M3_9BACT NAD-dependent deacetylase OS=Prevotella micans F0438 GN=HMPREF9140_01861 PE=4 SV=1
----------------------------------------RKIVFLTGAGMSVESGFKTFRGNDGLWENYPVEQVATHEGWENNPTLVTNFYNMLRKKLY
--DAEPNKGHKLIKDLEE-NYK-VTVITQNVDNLHEKAGSTNVIHLHGELTKVCSSREPYI-PENCEITPGMLAG-DGS--LLRPFIVFFNENVPMIEPA
AEVTSKADIFVIVGTSLNVYPAAGLVQYVPAT-APIFLIDPEEVNAS-WRITHIKKGASQGMEELIQEYRI--------
>tr|R6FRX0|R6FRX0_9BACT Putative NAD-dependent deacetylase OS=Prevotella sp. CAG:520 GN=BN691_01612 PE=4 SV=1
----------------------------------------KHIVFLTGAGMSVESGFKTFRGNDGLWENYPVDQVASHEGWLADPTLVTNFYNMLRRKLY
--AAQPNEGHRLIHELEK-DYK-VTVVTQNVDNLHEKAGSTNVIHLHGELTKVCSSRDVDQ-EDNCEVKPGTLAG-DGS--LERPFIVFFGESVPMISVA
AEAAEQADIFVIIGTSLNVYPAAGLIHYVRPS-APVYLIDPEPSMGV-RQFKHFQCGASEGMKRLCEELGVK-------
>tr|A0A0K9Q9Q7|A0A0K9Q9Q7_SPIOL Uncharacterized protein OS=Spinacia oleracea GN=SOVF_209330 PE=3 SV=1
----------------------------------------KNIVVLTGAGISAESGIPTFRDANGLWEGHDVMAVASIEGWKKNPALVQEFYNLRRKVAL
--AARPNAAHLALCQLES-AYQ-VTIITQNVDLLHEQAGSTKIIHLHGRLDQSKSSIDDRV---GDEIKMGDLCE-KGS--QLRPNIVWFGEAVPEIERA
MSYVSKADILIIIGTSLQVYPAAGLRQFAPNY-CRSFLIDKQIPNSTLGRIQCFEEAATTAVPILVAQLLKESS-----
>tr|A0A0M2XPA9|A0A0M2XPA9_9SPHI NAD-dependent deacetylase OS=Sphingobacterium sp. Ag1 GN=AAW12_24710 PE=3 SV=1
----------------------------------------KNIVVLTGAGISAESGIPTFRDANGLWEGHDVMEVASIEGWHKNPALVQEFYNLRRKAAL
--VAQANAAHYALVKLES-AYR-VSIVTQNVDLLHEQAGSSHIVHLHGRLDQSKSSVDDRV---GDEIKMGDLCE-KGS--QLRPNIVWFGEAVPAIEEA
ISLVSKADILIIVGTSLQVYPAAGLKEFAPSH-CKSFLIDKKIPHDNLRNIQCFEESATIAVPELVEQLLN--------
>tr|A0A088EWK9|A0A088EWK9_9SPHI NAD-dependent deacetylase OS=Sphingobacterium sp. ML3W GN=KO02_09720 PE=3 SV=1
----------------------------------------KKIVVFTGAGISAESGIQTFRDANGLWEGHDVSEVASIDGWYRNPELVQDFYNKRRETAM
--EAKPNAAHDALVRLAK-YFD-VQIITQNVDLLHERAGSVDVLHLHGRLDQACSSVDKSL--IGHEIKMGDLCD-KGS--QLRPNIVWFGESVPNMPTA
IAIAQAADIMLVIGTSLQVYPAASLVEVITHR-CDLYVVDKQINTTR-RKACAIERSASDAVPDLVEQLISRYR-----
>tr|A0A077XXF3|A0A077XXF3_9SPHI NAD-dependent protein deacylase OS=Sphingobacterium sp. PM2-P1-29 GN=cobB PE=3 SV=1
----------------------------------------KKIIVFTGAGISAESGIKTFRDADGLWEGHDVDDVASIDGWYRNPKLVQDFYNMRRQVAM
--QAKPNAAHQALVVLGK-SFD-VQIVTQNVDTLHERAGSDHVLHLHGRLDQACSSKDKKI--DGYEIKMGDLCE-KGS--QLRPNIVWFGEAVPNMEPA
LEMAREADIMIVIGTSLAVYPAAGLVDVIAPT-CDLYVVDKQINTSR-KRASTIESAASEAVPYLVAQLIERYA-----
>tr|D5ENI1|D5ENI1_CORAD Silent information regulator protein Sir2 OS=Coraliomargarita akajimensis (strain DSM 45221 / IAM 15411 / JCM 23193 / KCTC 1286
----------------------------------------LKVVVFSGAGMSAESGLQTFRGAGGLWEGHPVEAVATPEAWDRDPALVLRFYNERRRQLR
--QVKPNAGHLALAALEA-NYD-VHVVTQNVDDLHERGGSTRVLHLHGQLMQARSTVDEAI--KGRDIELGDRCV-RGG--QLRPNIVWFGEAVPAIERA
IEIVRSADILLVVGTSLQVYPAAALVHEARAA-RRRIYVDPHADAAS-GNFERFSLKAAECLPSLVEELCSQAT-----
>tr|N8Y0I1|N8Y0I1_9GAMM Uncharacterized protein OS=Acinetobacter schindleri NIPH 900 GN=F965_02166 PE=3 SV=1
----------------------------------------KKLVVFSGAGMSAESGINTFRDSDGLWEQHHVEDVATPEAWRRDPELVQRFYNERRKKIL
--AAQPNAAHQLIAELEV-AYD-IHVITQNIDDLHERAGSSKVIHLHGNIRMAKTSGPK-F---GAELDLKHLCT-DGY--PLRPHVVWFGEAVPAYAEA
QDCVQDTDIFIVIGTSLQVYPVAGLIHEIPLN-CSAYYIDPKANQQH-PPFEKIAMTATQGMQYLKDKLLNEAR-----
>tr|N9CH53|N9CH53_9GAMM Uncharacterized protein OS=Acinetobacter towneri DSM 14962 = CIP 107472 GN=F947_01290 PE=3 SV=1
----------------------------------------RKLVVFSGAGMSAESGINTFRDGDGLWEKHRVEDVASPEAWARNPELVQRFYNERRKNIL
--NAQPNLAHRLIAELED-DFD-VQVITQNIDDLHERAGSSEVLHLHGNIRLAKSSGPH-F---GDSLNLQDLCP-QGY--PLRPHVVWFGEAVPAYEEA
LDLIQDADIFIVIGTSLVVYPVAGLVHEIPAN-CQAYYIDPKAMQAQ-PAFQRISKTATEGMQQLFDQLHQV-------
>tr|N9M8F0|N9M8F0_9GAMM Uncharacterized protein OS=Acinetobacter sp. CIP 53.82 GN=F905_01193 PE=4 SV=1
----------------------------------------PKLIVFSGAGMSVESGINTFRDSDGLWEQHRVEDVATPEAWAKNPALVQRFYNERRKNIL
--NAQPNAAHQLIAELEQ-YFD-VAVITQNIDDLHERAGSQQVLHLHGNIRLAKTSGPD-F---GAELDLRDVCD-AGY--PLRPHVVWFGEAVPAYEQA
IEWVQDADIFIVIGSSLAVYPVAGLVHEIPAS-CQAFYIDPKANQQH-PAYECIAATATQGLAQLKPRLLAAL------
>tr|U2JHD9|U2JHD9_9BACT NAD-dependent deacetylase OS=Prevotella disiens JCM 6334 = ATCC 29426 GN=HMPREF0653_00631 PE=4 SV=1
----------------------------------------KKIVFLTGAGMSVDSGFKTFRGSDGLWEDFPVEQVATHEGWLKDPVLVNNFYNNLRKKLF
--QAQPNEGHKLIKSLEE-KYD-VTVITQNVDDLHERAGSTKVIHLHGELKKACSSNDEYI-EENPEIKPGEKAK-DGS--LLRPFIVFFGESVPMIEPA
AAAVSEADIFVIVGTSLNVYPAAGLVRYVRPN-IPIYLIDPNEVVPT-VNITSIKKGASEGMHDLIEMI----------
>tr|R6ABD7|R6ABD7_9BACT Uncharacterized protein OS=Prevotella sp. CAG:5226 GN=BN693_00520 PE=3 SV=1
----------------------------------------KKIVALTGAGISAESGFSTFRGAGGLWGRYPVEQVATPEGWAADPDLVTDFYNGLRSQLD
--EAAPNAGHRILAELEK-DFD-VTVVTQNVDDLHERAGSTNVIHLHGELRDVCSSAAPNR-PGEV-VEHGQLSG-DGS--LERPFIVWFGEAVPMLEVA
AEAAARADVFLIVGTSLNVYPAAGLIGYVPAG-AEVMLVDPNPVRVP-TRVEVIAEPASRGMEVVRERLRAVMG-----
>tr|A0A0D6EDT2|A0A0D6EDT2_9GAMM NAD-dependent protein deacylase OS=Halomonas sp. R57-5 GN=HALO3970 PE=3 SV=1
----------------------------------------PHLVVFTGSGISAESGIKTFRASDGLWENHPVEDVATPEAWQRNPQQVLDFYNQRREQIR
--RAKPNAAHKALAGLEHDGFN-VSIITQNIDDLHERAGSRQVLHLHGEILKARSSIDERR---KGGIELGHVCD-KGS--QLRPDVVWFGESVPLFEDA
CELVSQADFLLVVGTSLAVMPAASLLSYIDYD-TPCALVDPEADSLSPGV--AINTTAGEGVPALVNRWKQQGN-----
>tr|A0A0N8KJG9|A0A0N8KJG9_9GAMM NAD-dependent deacetylase OS=Halomonas sp. HL-48 GN=npdA PE=4 SV=1
----------------------------------------PHLVVFTGSGISVESGIKTFRASDGLWEEHPVEEVATPEGWRHDPERVLTFYNQRRDQIR
--RAKPNAAHKALAALEQDGFK-VSVITQNIDDLHERAGSRHVVHLHGEILKARSSVDPRR---KGGIALGDVCD-KGS--QLRPDVVWFGESVPLFEDA
CEIASQADFFLVVGTSLAVMPAASLLSYIELD-TPCALVDPEADTLTPGV--AINTTAGEGVPALVNQWRKQGN-----
>tr|A0A060B3J4|A0A060B3J4_9GAMM NAD-dependent protein deacetylase OS=Halomonas campaniensis GN=FF32_09175 PE=3 SV=1
----------------------------------------PHLVVFTGSGISAESGIKTFRASDGLWEDHPVEEVATPAGWRRDPQRVLEFYNLRREQIR
--KAKPNAAHKALAALEKDGFR-VSVVTQNIDDLHERAGSRDVLHLHGEILKARSTVDVRR---KGGIALGDICD-KGS--QLRPDVVWFGESVPLFEDA
CELVSQADFLLVVGTSLAVMPAASLLSYIDLD-TPCALVDPDADALTPGV--AINTTAGEGVPALVNQWRKQGN-----
>tr|A0A0B1PWG7|A0A0B1PWG7_9GAMM NAD-dependent protein deacetylase OS=Halomonas hydrothermalis GN=PZ78_11400 PE=3 SV=1
----------------------------------------PHLVVLTGSGISAESGIKTFRASDGLWEDHPVEDVATPEGWRRNPERVLAFYDQRREQIR
--RAKPNAAHKALAALEQEGFR-VSVVTQNIDDLHERAGSRHVLHLHGEILKARSSVDARR---KGGIRLGEVCD-KGS--QLRPDVVWFGEAVPLFEEA
CELVSQADFLLVVGTSLAVMPAASLLTYIDYD-TPCALIDPDADALSPGV--AINTTAGEGVPALVHQWCKQGN-----
>tr|A0A0N0CZX2|A0A0N0CZX2_9BACT NAD-dependent deacetylase OS=bacterium 336/3 GN=AD998_08805 PE=3 SV=1
----------------------------------------KKVVVLSGAGISAESGIATFRDSNGLWEGHDVMEVASPMGWQKNPSLVLEFYNQRRKQAL
--TAEPNEGHKALANLEK-HFD-VTIITQNVDNLHEKAGSTNIIHLHGELFKARSTTDPNV---SWELNLGDKCE-KGS--QLRPHIVWFYEDVPLMETA
VYEAVAADIFIVVGTSMVVYPAAGLIDYINKE-VPKYIVDVKIPQIQYHNLNLIEDKASTGLTRLSEELIEKFA-----
>tr|A0A0P0CTM3|A0A0P0CTM3_9BACT NAD-dependent deacetylase OS=Rufibacter tibetensis GN=DC20_20045 PE=4 SV=1
----------------------------------------QKIVVLTGAGISAESGLATFRDSNGLWEGHDVMEVASPEGWHKNPDLVLEFYNQRRKSAL
--GVEPNAAHKALVALEK-KFN-VQIITQNVDNLHERAGSSNIMHLHGKLFESRSSLDENV---GWELKKGDLCE-KGS--QLRPNIVWFGEAVPLIEQA
AGETMTADYLLIIGTSLQVYPAAGLVSYAPHD-APIYLIDPNAPAVSRRNITIIQEKATIGVPALVKKLMEE-------
>tr|M7XTZ8|M7XTZ8_9BACT NAD-dependent protein deacetylase of SIR2 family OS=Mariniradius saccharolyticus AK6 GN=C943_01692 PE=3 SV=1
----------------------------------------KKLVVLTGAGISAESGISTFRDSGGLWEGHDVMEVASPEGWRKNRELVLDFYNQRRKQAL
--SCEPNAAHLELARLEE-HFE-VTIVTQNVDNLHEKAGSSKVIHLHGELFKVRSTLDPNI---GWELKLGDKCE-KGS--QLRPHIVWFGEMVPMMESA
IEHALSADIFAVIGTSLLVYPAAGLIEYTQKD-IPKYIIDKQIPAVNDPMLQKIRQPATIGTVIMAKEIIRKYA-----
>tr|L8JUF8|L8JUF8_9BACT NAD-dependent protein deacetylase of SIR2 family OS=Fulvivirga imtechensis AK7 GN=C900_01571 PE=3 SV=1
----------------------------------------QKVVVLTGAGISAESGIPTFRDADGLWEGHDVMEVASPQGWERNQELVLHFYNERRKTAL
--NAKPNTGHLALAKMEE-DFD-VTIITQNIDNLHEKAGSSKVIHLHGQLFQSRSTADENI--EGWELKLGDLCE-RGS--QLRPNVVWFGEMVPMMEVA
AEEVYKADIFIVAGTSLVVYPAAGLLSLAADE-IPKYVIDPKIPIVE-PNLYFVEEKASTGVERVRQLLLAGLT-----
>tr|S2E2I9|S2E2I9_9BACT NAD-dependent protein deacetylase of SIR2 family OS=Indibacter alkaliphilus LW1 GN=A33Q_1340 PE=3 SV=1
----------------------------------------KKLVVLTGAGISAESGISTFRDSGGLWEGHDIMEVASPDGWRKNKELVLDFYNKRRKQAL
--TVMPNEGHKELASLEK-YFE-VTIITQNVDNLHERAGSKNVIHLHGELFKSQSTLDPSI---GWEIKLGDKCE-KGS--QLRPFIVWFGELVPKIEPA
IEIAKEADIFAVIGTSLLVYPAAGLIQYAPSH-IPKYIIDVNIPQIAVKNLRKIEAPASIGTKEMAQELIEKYA-----
>tr|A0A0H4W5J1|A0A0H4W5J1_9BACT NAD-dependent deacetylase OS=Rufibacter sp. DG31D GN=TH63_08485 PE=3 SV=1
----------------------------------------RKVVVLTGAGISAESGLATFRDANGLWEGHDVMAVASPEGWEKDPELVLEFYNQRRKSAQ
--GVEPNAAHKALVDLEE-KFE-VIIITQNVDDLHERAGSSQILHLHGKLFESRSTKDENI---GWQLNLGDLCE-KGS--QLRPNIVWFGEAVPLIEKA
AEETMSADYLLVIGTSLQVYPAAGLLSYAPHD-TPVYLVDPNVPSISRRNLKVIQEKATIGVPALVKQLLEE-------
>tr|F8EBZ5|F8EBZ5_RUNSL NAD-dependent deacetylase OS=Runella slithyformis (strain ATCC 29530 / DSM 19594 / LMG 11500 / NCIMB 11436 / LSU 4) GN=Runsl_01
----------------------------------------KKLVVLSGAGISAESGIKTFRDSDGLWEGHSIEDVATPQGWQRNPQLVLDFYNERRKQGL
--TAQPNAAHLILAELEK-YFD-VQIITQNVDNLHEKAGSTKVLHLHGELYKSRSTKDPSV---GWELKLGDKCE-LGS--QLRPNIVWFQEEVPMMVPA
VEMAEQAEIFIVVGTSLVVYPAAGLVYYVPPR-VPIFVVDPKTPEMSTKYVTFIPEKATVGMTMLRDKLLKEYL-----
>tr|A0A0H4PIF1|A0A0H4PIF1_9BACT NAD-dependent protein deacetylase of SIR2 family OS=Cyclobacterium amurskyense GN=CA2015_3441 PE=4 SV=1
----------------------------------------KNLVVLTGAGISAESGIKTFRDDNGLWEGHDVMEVASPEGWNKDKEKVLEFYNSRRKTGL
--YAKPNEAHLKLSELEK-KYK-VTIITQNVDDLHEKAGSSTVLHLHGELFKAQSTIDPKV---GWELKIGDKCE-KGS--QLRPYIVWFGEPVPMMTSA
ISAVENADALVIIGTSMLVYPAAGLIDYTRKE-IPKFVIDPIIPHIPQENIFFIEEKASTGVKKLEKLLK-NWK-----
>tr|Q2S770|Q2S770_HAHCH NAD-dependent protein deacetylases, SIR2 family OS=Hahella chejuensis (strain KCTC 2396) GN=HCH_06886 PE=4 SV=1
----------------------------------------KHIVVITGAGISAESGIQTYRGENGLWRETDYNEVASLIGWRKDREKVLTYWNAQRRIMA
--AAQPNAAHYALSRLE-ECYL-VSIITQNVDDLHERAGSNQVLHIHGELMKSRSSVNPKV---DRDINLGDKCE-RGS--QLRPDVVWFGEPVPLFSQA
QKIVHSADIMLVVGTSLEVYPAAYLVEKRVRG-VPMYIVDPNADSEAD-A--VINEPATQGVVTLVEQLLEQA------
>tr|U5C0B6|U5C0B6_9BACT Uncharacterized protein OS=Rhodonellum psychrophilum GCM71 = DSM 17998 GN=P872_18250 PE=3 SV=1
----------------------------------------KKLVVLTGAGISAESGIRTFRDSDGLWEGHDVMEVASPEGWRKNKILVLDFYNQRRKQAL
--AVKPNAGHLELARLEK-HFD-VSIVTQNVDNLHERAGSSKVIHLHGELFKSQSTLDPSV---SWEIKLGDTCK-KGS--QLRPFIVWFGEMVPMMDKA
IEICSNADIFAVVGTSLMVYPAAGLLQYAPKE-IPKYIVDVSIPATGIENLHVIQAPATIGVAQMAKEILSQFT-----
>tr|K1L793|K1L793_9BACT NAD-dependent deacetylase OS=Cecembia lonarensis LW9 GN=cobB PE=4 SV=1
----------------------------------------KKLVVLTGAGISAESGINTFRDAGGLWEGHDVMEVASPEGWRKNRELVLDFYNQRRKQAL
--SCEPNGAHLELAHLEE-FFD-VTIITQNVDHLHEKAGSSKIIHLHGELFKAQSTADPSV---GWEIKPGDKCE-KGS--QLRPFVVWFGEMVPMMEPA
IEEALRADIFAVIGTSLLVYPAAGLIQYAPKN-IPKYIVDIQIPELGVDQLRRIEAPASIGTKLMSEEIIKNYA-----
>tr|L0G2Z5|L0G2Z5_ECHVK NAD-dependent protein deacetylase, SIR2 family OS=Echinicola vietnamensis (strain DSM 17526 / LMG 23754 / KMM 6221) GN=Echvi_31
----------------------------------------KKLVVLTGAGISAESGIKTFRDSNGLWEGHDVMEVATPEGWQKNKKLVLDFYNQRRKQSL
--EVEPNGAHFGLAALEK-DFD-VTIVTQNVDNLHERAGSTNVIHLHGELAKSQSTLDPSV--DHWEIKLGDKCE-KGS--QLRPFIVWFGEMVPMMEPA
ARAAQEADIFAVIGTSMLVYPAAGLIQYTAEE-IPKYIIDVKIPKIG-NNLIKIEDFASSGVGKMMSMIEVSK------
>tr|R7ZTW4|R7ZTW4_9BACT NAD-dependent protein deacetylase of SIR2 family OS=Cyclobacteriaceae bacterium AK24 GN=ADIS_2013 PE=3 SV=1
----------------------------------------KKLVVLTGAGISAESGIATFRDANGLWEGHDIMEVASPEGWKKNKELVLDFYNQRRRACL
--NAEPNAAHLILAELEN-DLE-VTIVTQNVDDLHEKAGSTRIIHLHGELFKSQSTIDPRV---GTELNQGDTCE-RGS--QLRPFIVWFGEAVPMMAAA
ISAAKEADFFAIVGTSLLVYPAAGLIDYVSEV-VPLFIVDPKIPQIPAPRLIKLEEAASTGVAKMADMLR-SWL-----
>tr|A0A0E3UXY3|A0A0E3UXY3_9BACT NAD-dependent deacetylase OS=Pontibacter korlensis GN=PKOR_17995 PE=3 SV=1
----------------------------------------KKLVVLSGAGISAESGIATFRDADGLWEGHDVMEVASPEGWHRNPELVLDFYNQRRKNAH
--TVEPNAAHLTLADLEK-EFD-VRIITQNVDDLHERAGSTNVIHLHGKLFESRSTLDPTV---GWELKKGDKCE-RGS--QLRPNIVWFGEPVPMMEKA
IEETLQADIFLVVGTSLIVYPAAGLVDYVSSD-APIFVVDPNLPSMRRDNVHRFEEKASTGMQKVAQLLREKYI-----
>tr|S7WVN4|S7WVN4_9BACT NAD-dependent protein deacetylase of SIR2 family OS=Cyclobacterium qasimii M12-11B GN=ADICYQ_0810 PE=4 SV=1
----------------------------------------KHLVILTGAGISAESGLKTFRDDNGLWEGHDVMEVASPKGWENDKEKVLNFYNLRRKACL
--NAKPNKAHLKLAALED-TYK-ITIITQNVDNLHEIAGSSSVLHLHGELFKAQSTIDPNI---GWELNLGDKCE-KGS--QLRPYIVWFGEPVPKMSQA
ILEVESADALAVIGTSMLVYPAAGLIDFAAKG-IPKFIIDPKIPVLNQENIFAIKEKASTGVNKLENLLK-NWN-----
>tr|G0J030|G0J030_CYCMS NAD-dependent deacetylase OS=Cyclobacterium marinum (strain ATCC 25205 / DSM 745) GN=Cycma_3571 PE=3 SV=1
----------------------------------------KNIVVLTGAGISAESGLRTFRDDNGLWEGHDIMEVASPEGWNNNKAKVLEFYNARRQACL
--KAKPNQAHLKLAELEK-SHD-VTIITQNVDNLHELAGSSKVIHLHGELFKSQSTKDPNI---GWELKLGDTCE-KGS--QLRPFIVWFGEAVPKMKEA
IEAVEKADALVIVGTSMLVYPAAGLIDYAPEK-ILKIIIDLKIPYLSRNNITCIEEKASSGILKMENILK-SWN-----
>tr|C9LH16|C9LH16_9BACT Transcriptional regulator, Sir2 family OS=Alloprevotella tannerae ATCC 51259 GN=GCWU000325_01517 PE=3 SV=1
----------------------------------------QKLVILSGAGMSAESGFSTFRDSDGLWERYPVEQVATPEGWRADPTLVTNFYNHLRRLLV
--NARPNEGHRGLVALEN-QFD-VTIVTQNVDDLHERAGSSHVIHLHGELMKACSSRDPDW-PERVEIHPGELAA-DGS--LLRPWIVWFGEAVPNLEQA
AKEVAKADIFVIIGSSLNVYPAAGLVRHVPDG-AKIFLIDPAEVHVP-NRITVLRLPASEGLKELRRRLLPDSE-----
>tr|J9GQ37|J9GQ37_9ZZZZ Transcriptional regulator, Sir2 family OS=gut metagenome GN=EVA_01303 PE=3 SV=1
----------------------------------------KKLVVLSGAGISAESGISTFRDSGGLWDTYPVEAVATPEGWLADPNLVTDFYNTRRKELL
--QAHPNAAHRLLAELES-DYR-VTVVTQNVDDLHERAGSSHVIHLHGELMKVCSSREPNI-PEHCEVEHGTRAI-DGS--LLRPWIVWFGEAVPRLEDA
VLEVEEADIFVIIGTSLNVYPAAGLIHYVKPS-AKIYLIDPKPVSVP-NIVEVIQKVASVGMEILKTKLKALC------
>tr|R5GLK0|R5GLK0_9BACT Transcriptional regulator Sir2 family OS=Prevotella sp. CAG:755 GN=BN773_00654 PE=3 SV=1
----------------------------------------KKIVVLTGAGISAESGLSTFRDAGGLWDNYPVEQVATPEGWARDPALVTRFYNNLRRQLL
--SVRPSRAHELLARLEQ-HYD-VTVVTQNVDDLHERAGSTRVIHLHGELMKVASSRDPDI-PEEAEVEPGTLAP-DGS--LLRPWIVWFGEAVPNMEPA
CAAAEKADIFVVIGTSLNVYPAAGLVRYAPAS-APLYVIDPKPVPVA-SPLHFFQTTASAGMELLWKELVSDPE-----
>tr|G5GCL1|G5GCL1_9BACT Uncharacterized protein OS=Alloprevotella rava F0323 GN=HMPREF9332_01312 PE=3 SV=1
----------------------------------------KKLVVLTGAGISAESGFETFRDTGGLWEKYPVEQVATPEGWLRDPDLVTDFYNGLRKQLP
--TAQPNAGHLVLAEMEQ-DYD-VTVITQNVDDLHERAGSHRVIHLHGELMRVCSSRDPDW-ADRLEVRHGEKAK-DGS--LLRPWIVWFGEAVPNLDLA
AREVEQADIFAVIGSSLNVYPAAGLIRYAPAD-SPIFLIDPKPVRVP-RRVEVIQEVASKGVALLRDRLKQLD------
>tr|A0A0A2F6V3|A0A0A2F6V3_9PORP Uncharacterized protein OS=Porphyromonas sp. COT-290 OH860 GN=HQ41_00175 PE=3 SV=1
----------------------------------------KKLVILSGAGMSAESGLATFRDSDGLWMNHRVEDVASIEGFYRNPQLVLDFYAMRRREAE
--QATPNAGHLAIAALEQ-DYE-VYVITQNVDDLHERAGSTQVIHLHGELTKNCSVKNRQT-PKTLALKVGDLAP-DGS--QLRPFIVWFGEDVPMMVPA
IELAEQADIFVVVGTSLNVYPAAGLLGYVPHS-TPVYLIDPKPVSSA-SQIHWIEAGASQGLSQLRDLLAEAEK-----
>tr|U2IDH2|U2IDH2_9PORP NAD-dependent deacetylase OS=Porphyromonas sp. oral taxon 278 str. W7784 GN=HMPREF1556_01009 PE=3 SV=1
----------------------------------------PHLVVLSGAGMSAESGLSTFRDSDGLWAGHNVQEVASIEGWEQDPQRVLDFYNMRRREFV
--GAQPNEGHRLLAELER-RYR-VTIVTQNVDDLHERAGSTHVIHLHGELMKNRSVRNART-GATLELHVGDLAP-DGY--QLRPFIVWFGEEVPEMIPA
IEATERADLFLVIGTSLEVYPAAGLLGYVPHR-APVYCIDPKPVRSS-PDLIHFETGATEGMRRLYDLLMK--------
>tr|L1NA27|L1NA27_9PORP NAD-dependent deacetylase OS=Porphyromonas catoniae F0037 GN=HMPREF9134_01559 PE=3 SV=1
----------------------------------------LHLVVLTGAGMSAESGLSTFRDSDGLWAGCSPQEVASVEGWASDPQRVLDFYAERRREFD
--GAQPNEGHRLLASLED-RYR-VTIITQNVDDLHERAGSSEVIHLHGELMKNRSVRDPYT-PDTSALHVGDMAP-DGS--QLRPFIVWFGEEVPNMIPA
IEATEGADLFVVIGTSLEVYPAAALLGYTRRD-CPVFLIDPKPVHST-PDLIQIQKGASEGVRELCHRLRQAEE-----
>tr|J4VMZ5|J4VMZ5_9PORP NAD-dependent deacetylase OS=Porphyromonas sp. oral taxon 279 str. F0450 GN=npdA PE=3 SV=1
----------------------------------------PHLVVLSGAGMSAESGLSTFRDSDGLWAGHDVQEVASIEGWYRDPQCVLDFYNQRRREFV
--GAEPNEGHRLLSRLEE-YYR-VTIVTQNVDDLHERAGSSRVIHLHGELMKNRSVRDPFT-GATRELHIGDLAP-DGT--QLRPFIVWFGEEVPEMIPA
IEATEEADIFLVIGTSLEVYPAAGLLGYVPGK-APVYCIDPKPVRSG-PDLIHIQAGAVAGMRDLYARLTEGC------
>tr|A0A0A2E1G9|A0A0A2E1G9_9PORP Uncharacterized protein OS=Porphyromonas sp. COT-239 OH1446 GN=HQ37_03070 PE=3 SV=1
----------------------------------------PHIVVLTGAGMSAESGLATFRDSDGLWAKHRVEDVASIEGFYHNPQLVLDFYAMRRREAF
--AAKPNQGHIALAQLEQAGYR-VDIITQNVDDLHERAGSSSVIHLHGELTKNCSVAHRQT-PETLALKVGDLAP-DGS--QLRPFIVWFGEEVPMMESA
ARLVEVADLLVIVGTSLGVYPAASLVGYAPRT-TPIILIDPKPVVSA-HDIEHIALGASKGLEELKRRITEGGI-----
>tr|R6L9K3|R6L9K3_9BACE NAD-dependent deacetylase OS=Bacteroides clarus CAG:160 GN=BN507_01290 PE=3 SV=1
----------------------------------------KNLVVLSGAGMSAESGISTFRDAGGLWDKYPVEQVATPEGYARNPELVINFYNERRKQLL
--DVEPNAGHIGLAGLEK-DFN-VTVVTQNVDNLHERAGSKRVIHLHGELTKVCSSRAPYI-PDEYEVKLGDKAG-DGT--QLRPFIVWFGEAVPEIETA
VNYVEKADIFVIIGTSMNVYPAAGLLNYVPRE-AEVYLIDPKPVDVH-TRIHIIQKGASEGVQELRSLLKP--------
>tr|J9FIM7|J9FIM7_9ZZZZ Transcriptional regulator, Sir2 family OS=gut metagenome GN=EVA_17133 PE=3 SV=1
----------------------------------------KKLVVLSGAGMSAESGISTFRDAGGLWDKYPVEQVATPEGYARNPELVINFYNERRKQLL
--EVVPNEGHRGLVALEN-EFE-VTVITQNVDNLHERAGSKQVIHLHGELTKVCSSKDPQV-PEEYEVHWGDKAE-DGS--QLRPYIVWFGEPVPAIETA
IAYVQQADVFVIIGTSLNVYPAAGLLHYVPAR-TAVYLIDPKPVDTH-SRIHVIQKGASEGVRELSRLLLSK-------
>tr|D2EXM4|D2EXM4_9BACE NAD-dependent deacetylase OS=Bacteroides sp. D20 GN=npdA PE=3 SV=1
----------------------------------------KNLVILSGAGMSAESGISTFRDAGGLWDKYPVEQVATPEGYARNPELVINFYNERRKQLL
--DVVPNAGHLGVADLER-DFN-VTVVTQNVDNLHERAGSTHVIHLHGELTKVCSSRDPYV-PEEYEVKLGDKAG-DGT--QLRPFIVWFGESVPEIETA
IRYVEQADIFVIIGTSLNVYPAAGLLNYVPRA-AEVYLIDPKPVDTH-MRIHVIQKGASEGVKELKALLTVTQP-----
>tr|R5FTQ1|R5FTQ1_9PORP Transcriptional regulator OS=Porphyromonas sp. CAG:1061 GN=BN460_00364 PE=3 SV=1
----------------------------------------KKLVALTGAGISAESGIATFRDSDGLWEHYSVEEVASAEGYRRNPKLVIDFANDRREQCV
--NAQPNQGHKLLAELEK-EYD-VTVITQNIDDLHERAGSSHIIHLHGELMKCCSENDLSP-EGRLRMTTEDRDA-QGH--RLRPFIVYFGEPVPRMEDA
VREVETADIFVIIGTSLNVYPAAGLVQFVPRG-TPIYLIDPKDVPGS-SQFVHIKMGAGKGMAELINKLHNS-------
>tr|F9EXN2|F9EXN2_9NEIS SIR2 family NAD-dependent deacetylase OS=Neisseria macacae ATCC 33926 GN=cobB PE=4 SV=1
----------------------------------------KKCVVLTGAGISADSGLLTFRDAGGLWEGHRVTDVCTPEALARNPKLVIDFYNQRRLQAN
--AAEPNAAHLALVKLAQ-YYD-VHIITQNVDALHEKAGSSKVLHLHGELNKLRSTIDEDI--TGE-QTDDVRDS-QGN--PMRPHIVFFGEQVPMFDAA
VEEMRDADVVMIVGTSMQVYPAASLIHYAPPA-AERYLVDPNPQGV--ADVEVIPKRAAEGVPALVEHLISRA------
>tr|A0A0J1C4T9|A0A0J1C4T9_9NEIS NAD-dependent deacetylase OS=Neisseria sp. KH1503 GN=PL75_03685 PE=3 SV=1
----------------------------------------KKCVVLSGAGISADSGLKTFRDAGGLWEGHRVEDVATPEAFAKNPQLVLDFYNQRRRQAA
--EALPNEGHYALVALEE-YFD-VRIITQNVDDLHERAGSSNVLHLHGELNKIRSTRDEHIVVWQGDQSLEDTDA-EGC--LMRPHIVWFGEEVPMFEKA
LEEVAGADILIVVGTSLQVYPAASLLQYAPPH-ADIYLVDPNPKQVG-ARVEVIAKTAKEGLPSLVDYLVKQRI-----
>tr|G2DMZ1|G2DMZ1_9NEIS NAD-dependent deacetylase OS=Neisseria weaveri LMG 5135 GN=l11_17410 PE=3 SV=1
----------------------------------------KTCVILSGAGISADSGLQTFRDTGGLWEGYRIEEVCTPEAFQNQPQKVIDFYNLRREQAE
--AAEPNAAHLALVELER-HYQ-VEIVTQNVDDLHERAGSKHVLHLHGELNKLRSCTDESIIAWRGKQNPTDTDS-RGN--PLRPHIVWFGEDVPLFPQA
VETVARADILIIVGTSLQVYPAASLMHYAKPM-AEIYLVDPKPQTRL-PHIEVISKTAAEGVPGLVEYLISKAG-----
>tr|A0A0P7JK79|A0A0P7JK79_9NEIS NAD-dependent deacetylase OS=Neisseria sp. 83E34 GN=AKG09_01015 PE=4 SV=1
----------------------------------------KTCIILTGAGMSADSGLKTFRDAGGLWEGYRVEEVCTPEAFARNPQLVLDFYNQRRKQAE
--QASPNAAHLALTKLEP-HYH-VQIITQNVDNLHERAGSNHVLHLHGELSKLRSTLDETIIEWTGDQTLSDTNS-KGH--PLRPHIVWFGEDVPLFPKA
VAMMHEADVVLIIGTSLQVYPAASLLHYAPPH-ADIYLVDPNPQASG-AHIEIVPKKAAEGVPPLVDYLIEKAK-----
>tr|D4DSG6|D4DSG6_NEIEG NAD-dependent deacetylase OS=Neisseria elongata subsp. glycolytica ATCC 29315 GN=npdA PE=3 SV=1
----------------------------------------KKCVVLTGAGISAESGLQTFRDSGGLWEGYRVEDVCTPEAFARSPQTVIDFYNARRRAAA
--VAEPNAAHFALADLER-AYD-VQIITQNVDDLHERAGSSKVLHLHGELNKLRSTVDENI--QGD-QTLADRDS-RGY--PLRPHIVWFGEAVPLIGEA
VRLVGAADTVIVVGTSLKVYPAASLLHYARFG-VPVYLIDPKPNAD--SGVEILAQTAVRGVPALVAELLRAAE-----
>tr|F2BC74|F2BC74_9NEIS SIR2 family NAD-dependent deacetylase OS=Neisseria bacilliformis ATCC BAA-1200 GN=cobB PE=3 SV=1
----------------------------------------KTLAVLTGAGISAQSGLQTFRDSDGLWEGYRVEDVCTPEAFARNPQAVIGFYNQRRRAAA
--AAVPNAAHKALADLEK-HYR-VRIITQNVDDLHERAGSSSVLHLHGELGKLRSTADETI--QGD-QTAADRDR-HGN--PLRPHIVFFGEAVPLMDEA
VRLVSAADIVMVVGTSLQVYPAASLLHYARAD-APLYLVDPKPNIT--ARVEVLAKTAAEGVPQLAAELIAAAQ-----
>tr|L1NKQ1|L1NKQ1_9NEIS NAD-dependent deacetylase OS=Neisseria sp. oral taxon 020 str. F0370 GN=HMPREF9120_02406 PE=3 SV=1
----------------------------------------KKCVALTGAGISAESGLQTFRDSDGLWEGWRIEDVCTPEAFARQPQVVIDFYNKRRRKAA
--AAKPNAAHKALAELEK-YYD-VQIITQNVDNLHERAGSSKVLHLHGELDKLRSTADETV--SGD-QKPSDCDR-YGN--PLRPHIVWFGEAVPLMDKA
AGMVCGADIVMVVGTSLQVYPAASLLHYARSD-APVYLVDPKPNLN--VRAEVLAKKAAEGVPQLVGELIAAAR-----
>tr|D7MZD0|D7MZD0_9NEIS NAD-dependent deacetylase OS=Neisseria sp. oral taxon 014 str. F0314 GN=npdA PE=3 SV=1
----------------------------------------KKCVVLTGAGISADSGLLTFRDAGGLWEGHKVTDVCTPEALERNPKLVIDFYNQRRLQAN
--AAEPNAAHKALAELEK-YYD-VHIITQNVDGLHEKAGSSKVLHLHGELNKLRSVADENI--TGE-QTDDVRDS-KGG--PMRPHIVFFGEEVPLFPQA
AEEMRDADVVIIVGTSMQVYPAASLIHYAPPD-ADCYLVDPNPQGV--AGVEVIAERAASGVPKLAEYLIGRAG-----
>tr|A0A0P7J2A2|A0A0P7J2A2_9NEIS NAD-dependent deacetylase OS=Neisseria sp. 74A18 GN=AKG43_06210 PE=4 SV=1
----------------------------------------KKCVVLTGAGISAESGLKTFRDAGGLWEGYKVSEVCTPQAFERDPQTVLSFYNMRRRQAN
--AAEPNAAHESLVRLER-HYR-VHIITQNVDDLHERAGSSRVLHLHGELNKVRSCVDESV--TGD-LTINDTDS-RGR--PLRPHIVWFGEEVQLFPQA
VEEMRDADIVMVVGTSLQVYPAASLLNFAPPE-AECFLVDPNPQHA--APVEILPKKACEGVPELVEELIRRAE-----
>tr|N8U0T4|N8U0T4_9GAMM Uncharacterized protein OS=Acinetobacter sp. ANC 3789 GN=F975_01150 PE=4 SV=1
----------------------------------------QKLVVFSGAGMSAESGIHTFRDSNGLWENHAIEDVATPEAWARQPELVQRFYNERRKQIL
--AAQPNLAHQLIARLQV-YFD-VSVITQNIDDLHERAGNLKVTHLHGNIRFAKSSAPNHY---GWELCLRDFAD-DGS--PLRPHVVWFGEAVPEYAIA
QQIVRQADIFIVIGSTLVVYPVAGLVHEIPKH-CQAFYIDPKASHAA-PTYTLLNTTATQGMMQLFTQLIASSS-----
>tr|E6KWL8|E6KWL8_9PAST SIR2 family NAD-dependent deacetylase OS=Aggregatibacter segnis ATCC 33393 GN=cobB PE=3 SV=1
----------------------------------------PLCVVLSGAGISAESGIPTYRAVDGLWAGHKIEEVCTPEALQRNRKKVLDFYNERRRNCA
--VAQPNAAHKALVELER-GYN-VQIITQNVDDLHERAGSANVLHLHGELNKVRSSFDPGI---FGEQSVADKDP-NGH--PMRPHIVFFGENVPMLEPA
IDFVSKADVVLVIGTSLQVYPANGLVNEAPKN-APIYLIDPNPNTGF-PRVETVKMKAGEGVPKVVAELLGKVK-----
>tr|I1XTR8|I1XTR8_AGGAC Transcriptional regulator, Sir2 family OS=Aggregatibacter actinomycetemcomitans D7S-1 GN=D7S_02068 PE=3 SV=1
----------------------------------------PLCVVLSGAGISAESGIPTYRAEDGLWAGHKIEDVCTPEALQWNRKQLLSFYNERRRNCA
--EAKPNAAHKVLVELER-SYN-VQIITQNVDDLHERAGSTNVLHLHGELTKARSSFDPDI---TGDQSVNDKDP-NGH--PMRPHIVFFGESVPMLEPA
IDLVSQADIVLVIGTSLQVYPANGLVNEAPKN-AQIYLIDPNPNTGF-RHVNVVKMKAGEGVSKVVAELLGEAK-----
>tr|E1X7D6|E1X7D6_HAEI1 Deacetylase of acetyl-CoA synthetase, NAD-dependent OS=Haemophilus influenzae (strain 10810) GN=HIB_14720 PE=3 SV=1
----------------------------------------PICVVLTGAGISAESGIPTFRAEDGLWAGHKVEEVCTPEALQKNRAKVLDFYNQRRKNAA
--AAKPNAAHLALVELEK-AYD-VRIITQNVDDLHERAGSSKVLHLHGELNKARSSFDESI---FGDQKLEDKDP-NGH--PMRPYIVFFGEMVPMLERA
VDIVEQADVVLVIGTSLQVYPANGLVNEAPRK-APIYLIDPNPNTGF-RKVIAIKEKAGEGVPKVVAELLENTK-----
>tr|A0A077KCY3|A0A077KCY3_9FLAO SIR2 family NAD-dependent deacetylase OS=Chryseobacterium sp. StRB126 GN=cobB PE=4 SV=1
----------------------------------------KKLTILSGAGISAESGIKTFRDGDGLWENHNITDVASPEGWKKDRALVLEFYNQRRRQLH
--EVEPNDAHKLLAELEK-HFD-VQIITQNIDDLHERAGSTKILHIHGELFKSCSCNNKSI---KDDINIGDKAE-DGA--QLRPFIVWFGEDVPLYHDA
REMVKDSDILLVIGTSLRVYPASVLIDDIKDD-CLLIVINPNETGFG-GEAVVMKETATQGMKMLFDKLVDLA------
>tr|A0A0Q5QMZ6|A0A0Q5QMZ6_9FLAO NAD-dependent deacylase OS=Chryseobacterium sp. Leaf180 GN=ASG01_05275 PE=4 SV=1
----------------------------------------KKLTILSGAGISAESGIKTFRDGDGLWENHRVEDVASPEGWRKNPELVLDFYNERRRQLH
--EVHPNKAHFLLAELEK-YFD-VQIITQNIDDLHERAGSTKVLHLHGELFKSCSERNKNI---KEDIKLGNLAP-DGH--QLRPFIVWFGEEVPAMTEA
LEMTSHADIFLVIGTSLQVYPAAGLVHEINDS-CFLIVINPNETDFG-GKAVVLKETATKGMQILFDKLLDMQ------
>tr|A0A086BM36|A0A086BM36_9FLAO NAD-dependent deacetylase OS=Chryseobacterium piperi GN=IQ37_02170 PE=4 SV=1
----------------------------------------KKLTILSGAGISAESGIKTFRDGDGLWENHNVTDVASPEGWQKDRALVLEFYNQRRRQLH
--EVVPNDAHKLLADLEQ-YFD-VQIITQNIDDLHERAGSTHILHIHGELFKSCSSNNKNV---KGDINLGDKAE-DGA--QLRPFIVWFGEDVPLYHTA
REKVREADILIVIGTSLQVYPAAGLIHDIKDD-CLLIVINPNETEFG-GQAVVMKESATRGMKLLFDKLVNMA------
>tr|D7VUM8|D7VUM8_9FLAO Transcriptional regulator, Sir2 family OS=Chryseobacterium gleum ATCC 35910 GN=HMPREF0204_10226 PE=3 SV=1
----------------------------------------KKLTILSGAGISAESGIKTFRDGDGLWENHNITDVASPEGWRKDRALVLEFYNQRRRQLH
--EVKPNEAHQLLAELEK-YFE-VQIITQNIDDLHERAGSSNILHLHGELFKSCSCNNKNI---KDDIKIGDKAE-DGA--QLRPFIVWFGEDVPLYHTA
QEIVKESDILLVIGTSLQVYPAAGLIHDIKDD-CLLIVINPNETGFG-GQAVVIKETATQGMKLLFDKLVNLA------
>tr|E7RXB4|E7RXB4_9BURK NAD-dependent deacetylase OS=Lautropia mirabilis ATCC 51599 GN=npdA PE=3 SV=1
----------------------------------------RRIVVLSGAGISADSGLKTFRDSDGLWEGHRVDQVATPEAFARNPQLVIDFYNARRRQLL
--EAQPNAAHHALARLAG-HYD-VRIVTQNVDDLHERAGSRQVLHLHGELKKLRSSVDDDV--TRD-QTLADRDP-NGY--PMRPHIVWFGEAVPLIDLA
AEWVSQADAVLVVGTSMQVYPAAGLLECAQPG-TRCYLVDPRPPA---AGVEVIAARAAEGVPPLVDRLIAEAE-----
>tr|G4CIY8|G4CIY8_9NEIS SIR2 family NAD-dependent deacetylase OS=Neisseria shayeganii 871 GN=cobB PE=3 SV=1
----------------------------------------QSIVVLSGAGISADSGLKTFRDSDGLWEGHRVEQVATPEAFARDPQLVLDFYNARRRQLV
--QARPNAAHLALAELQA-HYD-VRIVTQNVNNLHERAGSRQVLHLHGELTKLRSSVDERV--QGD-QTLADADP-HGH--PLRPHIVWFGEPVPLIETA
AAWVAQADKVLVVGTSMKVYPAAGLLEYVRDG-AECFLVDPRPPAG--QGVEVLAAKAKDGVPELVRRLIGAG------
>tr|C0DRS4|C0DRS4_EIKCO NAD-dependent deacetylase OS=Eikenella corrodens ATCC 23834 GN=npdA PE=3 SV=1
----------------------------------------QKIVVLTGAGISADSGLRTFRDTDGLWEGYKVEEVCTPEAFARNPQLVIDFYNERRRQAQ
--AAEPNAAHRALAELEK-YYQ-IQIITQNVDDLHERAGSSTVLHLHGELNKARSSADENV--TGD-QSINDTDP-QGY--PMRPHIVWFGEAVPLIETA
ARWVSQADKVLVVGTSMQVYPAAGLLEYAPYE-TERYLVDPRPPKG--ANISIIEAKAKDGVPQLVDKLITEAA-----
>tr|B3T431|B3T431_9ARCH Putative Sir2 family protein OS=uncultured marine crenarchaeote HF4000_ANIW133K13 GN=ALOHA_HF4000ANIW133K13ctg1g15 PE=3 SV=1
----------------------------------------RKIVFVTGAGISQESGIPTFRGKDGHWRKHDPMRLASIDAFYDDPKLVWEWYEDRRKNIL
--EAKPNEGHFAISSMEKFR--DVVVLTQNIDGLHQRSGSTNVLELHGSIIRIKCTVCNFK-----FESL-PKCE-CGN--MLRPDVVWFGEALPQDINA
IKQASICDIMIIVGTSLAVSPANTLPLYAKQNSATLIEVNPE---------LSIQATSANALPTMLSILKNV-------
>tr|A0A075HXB5|A0A075HXB5_9ARCH Silent information regulator protein Sir2 (NpdA) OS=uncultured marine thaumarchaeote KM3_88_G03 GN=npdA PE=3 SV=1
----------------------------------------KKIVFVTGAGISQESGIPTFRGKDGHWRKHDPMKLASIDAFFDDPKLVWEWYEDRRKNIL
--AAKPNDGHFAISKMEKFK--DVVILTQNIDGLHQRSGSTNVLELHGSIIRIKCTVCNFE-----FESL-PKCE-CGN--MLRPDVVWFGEALPQDVNA
MEKASTCDMMIIAGTSLAVSPANTLPIYAKQNGATLIEVNPE---------LSIQTTSANALPKILAILKNQ-------
>tr|A0A075GS53|A0A075GS53_9ARCH Silent information regulator protein Sir2 (NpdA) OS=uncultured marine thaumarchaeote KM3_175_B03 GN=npdA PE=3 SV=1
----------------------------------------RKIVFVTGAGISQESGIPTFRGKDGHWRKYDPMKLASIDAFYDDPKLVWEWYEDRRKNIL
--AAKPNEGHFAISQMEEFK--DVIVLTQNIDGLHQRSGSTNVLELHGSIIRIKCTVCDFE-----FESL-PKCK-CGS--MLRPDVVWFGEPLPQNISA
MKEASVCDVMIIVGTSLVVSPANTLPVYAKQNGAILIEVNPE---------LSVQATSVETLPKLLSIFKNE-------
>tr|A8UPP6|A8UPP6_9FLAO NAD-dependent deacetylase OS=Flavobacteriales bacterium ALC-1 GN=FBALC1_05488 PE=4 SV=1
----------------------------------------KHIVVLTGAGMSAESGVKTFRDHDGLWEGHDVMKVASPKGFANNPELVLDFYNQRRRQLK
--TVEPNQAHKDLAALEV-DYK-VTIVTQNVDDLHERAGSSDVVHLHGELLKIRSTGNYNIQVWTEDINLGDTCK-KGY--QLRPHIVWFGEDVPMIETA
VKICYAADILIIIGTSMQVYPAASLINYVQPD-TTIFYIDPKPA-I-AGKVNVIAKSATEGMKELISILKTS-------
>tr|A0A024FJH0|A0A024FJH0_9FLAO NAD-dependent protein deacetylase of SIR2 family OS=Winogradskyella sp. PG-2 GN=WPG_2622 PE=3 SV=1
----------------------------------------KHIVVLTGAGMSAESGIKTFRDANGLWEGHDVMEVASPEGFRHNPELVLDFYNQRRRQLK
--EVEPNQAHKDLATLEH-DFK-VTIITQNVDDLHERAGCSDVVHLHGELRKIRSTGNQNIKVWEEDINLGDICE-KGY--QLRPHIVWFGEDVPMIDTA
IKICYAADILVIIGTSMQVYPAASLINYVQPD-TPIYYIDPKPA-I-TDKVTVIAKSATEGLKELIVELK---------
>tr|A0A0N0UNX0|A0A0N0UNX0_9FLAO Sir2 family protein OS=Polaribacter dokdonensis DSW-5 GN=I602_2250 PE=3 SV=1
----------------------------------------KNLVVLTGAGISAESGIKTFRDADGLWEGHDVMQVASPKGYLNNPELVLDFYNQRRRQLL
--TVKPNKAHYNLKELET-NYN-VQIITQNVDDLHERAGSTNIVHLHGELLKVRSTENENVIKWRKDLNLGDVCK-LGS--QLRPHIVWFGEMVPMLEMA
IEITKKADILVIIGTSLQVYPAASLIEFVKRN-VPIYFIDLNPNINEYKNLRIIKENATNGTDKLLNLLIQ--------
>tr|F4KQ65|F4KQ65_HALH1 NAD-dependent deacetylase OS=Haliscomenobacter hydrossis (strain ATCC 27775 / DSM 1100 / LMG 10767 / O) GN=Halhy_6407 PE=3 SV=1
----------------------------------------EKIVVLSGAGMSAESGISTFRDANGLWEQHDIMEVASIDGWRKNPGLVLEFYNQRRRQLK
--TVEPNAAHYALVELEK-KYA-VTIVTQNVDDLHERAGSSSIVHLHGELRKVRSAKHENIYHCEEDINLGDLCD-KGH--QLRPHIVWFGEMVPKIEIG
AQAVAACDHLIIIGTSMQVYPAAGLVDYAQGH-AAIYYIDPKPSISNYPEVTIIAEKATTGVRNLVDQLLNR-------
>tr|I2K7Z6|I2K7Z6_9PROT Silent information regulator protein sir2 OS=Sulfurovum sp. AR GN=SULAR_03842 PE=4 SV=1
----------------------------------------KKIMILSGAGLSAESGIHTFRDHDGLWENHDVMKVCSTQGWIEDHKYVTRFYNERRRDLK
--FKEPNPAHKVLAQLEYDYRGRIIHLTQNIDNLMEKAGAKDVIHLHGTLTDLRCEACTEY---P-E--G-EHCPHCGNT-RVRHNVVMFGEAAPEYSQE
AIRH--STLFIAIGTSGTVIDIVPIAKEFKHS----ILIDPKRQETA-KFAHFIQKKAGEAMDEMMAIIKDHMD-----
>tr|H5SMB4|H5SMB4_9BACT Silent information regulator protein Sir2 OS=uncultured Bacteroidetes bacterium GN=HGMM_F50B04C26 PE=3 SV=1
----------------------------------------RLVVVLTGAGISAESGLSTFRDSGGLWEKYSIYEVATPEAWQRNPQLVLDFYNQRRAQLA
--RVAPNPAHTLLKALEE-KYT-VIVITQNVDDLHERAGSSYILHLHGELTRARSTVDPSI--GYAPIRWGDTCE-KGS--QLRPHVVWFGEEVPAYPLA
ESWAQRADVFVVIGTSLQVYPAAGLLEEAWQA-KRKFLIDPRPTL-T-TGVEVLAKPASEGVRDLVEKLLS--------
>tr|E4RSM9|E4RSM9_LEAB4 Silent information regulator protein Sir2 OS=Leadbetterella byssophila (strain DSM 17132 / KACC 11308 / 4M15) GN=Lbys_0083 PE=4
----------------------------------------MNIVVLSGAGMSAESGLKTFRDMGGLWESFKIEDVATPEAFRKDPDTVLRFYNERRKQAY
--VAEPNPGHKLLAELEL-THS-VKIITQNVDGLHEKAGSRTVLHLHGELSKVRSTGNPEI--GGDSIKSGQLAE-DGF--PLRPHIVWFGEEVPLMPLA
EEWVAEAELFIVVGTSLQVYPAAGLLQYA--H-CPVWVIDPHKSNFN-SNVQFISLSASLGLRHLVQVLDLM-------
>tr|I2EZT4|I2EZT4_EMTOG NAD-dependent deacetylase OS=Emticicia oligotrophica (strain DSM 17448 / GPTSA100-15) GN=Emtol_4062 PE=3 SV=1
----------------------------------------KKLVVLSGAGISAESGIKTFRDTGGLWENHSIEEVATPEGWRKNPQLVLDFYNARRAQAA
--EAQPNAGHITLANLEA-YFD-VHIITQNVDSLHEKGGSSKVLHLHGELSKVRSVKNDKI---GKAIQLGDLAE-DGG--QLRPHIVWFGEMVPMIEPA
AELCMEADIFIVVGTSLQVYPAAGLIGYVDES-APKFIIDPNKPDVSYQNINFINETAAIGLPKLAQKLIEEYQ-----
>tr|A0A0A1Z1G1|A0A0A1Z1G1_PSEFL Uncharacterized protein OS=Pseudomonas fluorescens LMG 5329 GN=K814_0116240 PE=4 SV=1
----------------------------------------RKIVIFTGSGISAESGLDTFNDETGLWMDHRVEDVATPEAWHRHPADVLAFYNALRHKAW
--TAQPNAAHRAIAELE-QQFD-VVVITQNVDDLHERAGSTCVLHLHGQINLAQSTVDEQT---DKPILLGDTCE-KGS--QLRPHIVWYGENVPNIEKA
LQHFKNAEKVLVVGTSLTTQPAAGLVTKARHS-AEKVLIGLAVS-RKYGY--FMRGKASSLVPYVVGCWLKGQK-----
>tr|A0A0K8QZG3|A0A0K8QZG3_9BACT NAD-dependent protein deacetylase, SIR2 family OS=Bacteroidales bacterium 6E GN=BA6E_121178 PE=3 SV=1
----------------------------------------QKLVVLSGAGMSQESGLKTFRDMGGIWDNYHVEEVASPEAWKKNPELVLRFYNERRKALW
--EARPNAGHIALASLED-RYD-VEIITQNVDDLHEQAGSRKILHLHGELRKARSTADPSI--HTPELNIGDVCE-LGS--QLRPHIVWFGEPVPNIVKA
QKIMEKADILVVIGTSLVVYPAAGLIHFAPEG-IPIYVIDPGSPNLT-SGVVYIQKKASEGVNDLLEKLEHYRL-----
>tr|A0A0H5AUJ3|A0A0H5AUJ3_9PSED NAD-dependent protein deacetylase OS=Pseudomonas trivialis GN=AA957_18985 PE=4 SV=1
----------------------------------------QKIVIFTGSGISAESGLDTFNDETGLWMNHRIEDIATPEAWHRHPGDVLAFYNELRQKAG
--AAQPNAAHRAIAELE-SRFD-VVVITQNVDDLHERAGSTCVLHLHGQINLAQSTVDEQV---DNPISLGDLCE-KGS--QLRPHVVWYGENVPNIEKA
QQHFKNAQKVLVVGTSLTTQPAAGLVARASYP-AEKILIGLAVS-RKYGY--FMRGKASSLVPYVVGCWLKGQR-----
>tr|K9UIY6|K9UIY6_9CHRO NAD-dependent protein deacetylase, SIR2 family OS=Chamaesiphon minutus PCC 6605 GN=Cha6605_3398 PE=4 SV=1
----------------------------------------NRVVIFSGAGISAESGLTTFRDRNGLWSRSKIEDVATPSAWEADPEIVLQFYNERRIQTA
--KAQPNAAHLAIAELE-AKYE-VIVITQNIDDLHERAGSSKIIHVHGEITKARSSIDSSI---DRQIQLGDKCE-KDS--QLRPHVVWFGEDIQNFEVA
RAALNTAGKVLVIGTSLTVYPAASLLNRARFH-AEKILVSLEID-KKFGY--CWSEKASIAVPNIVRRWLEGEY-----
>tr|H1Y7F7|H1Y7F7_9SPHI NAD-dependent deacetylase OS=Mucilaginibacter paludis DSM 18603 GN=Mucpa_5303 PE=3 SV=1
----------------------------------------GEIVVLTGAGISAESGLKTFRDSDGLWEGYNIEDVATPEAWQRNPALVQDFYNQRRKSVL
--EAQPNVAHYALARLEE-KYK-VTIITQNIDDLHERAGSTNVVHLHGIITRSQSSRNART--KGWELRMDEVCE-LGS--PLRPHVVWFGEMVPMIETA
AQICSTADLFILVGTSLAVYPASGLINYVPDE-VPKYIVDPKIPTVY-DNLTKIEAKASIGVPELVDELMKVDA-----
>tr|C6Y0J4|C6Y0J4_PEDHD Silent information regulator protein Sir2 OS=Pedobacter heparinus (strain ATCC 13125 / DSM 2366 / NCIB 9290) GN=Phep_0531 PE=4 
----------------------------------------KRVVILTDAGISAESGLKTFRDADGLWEGYNIADVATPEAWKRNPELVQRFYNERRKSVI
--EAQPNAAHKALTLLQT-KYN-VHIITQNIDDLHERAGAENVLHLHGIITRSQSDVDSAT--EGWEIGPSAVCE-YGM--PLRPHVVWFGENVPNLMPA
AKICAKADIFAVIGTSLVVYPAAGLTDYVPDT-ALKYAVDPNIPQIK-N-FKRIEKAATIGVPEMVKELMNLA------
>tr|A0A0P0NN96|A0A0P0NN96_9SPHI NAD-dependent deacetylase OS=Pedobacter sp. PACM 27299 GN=AQ505_10005 PE=4 SV=1
----------------------------------------KKLVVLTGAGISAESGLKTFRDTDGLWEGFNVYDVATPEAWRKNPEMVQDFYNQRRKQVL
--LAQPNDAHRALAELEA-DYD-VHIITQNIDDLHERAGSTKVTHLHGVITRSQSDGNPDT--NGWELKMGEFCE-LGT--QLRAHVVWFGEAVPMIEEA
AKICAAAEVFVLIGSSLAVYPAAGLIDFVPAQ-SPIYIIDPKIPQVR-HQVIKIEKRAVSGMRDLVELLT---------
>tr|A0A0C1D549|A0A0C1D549_9SPHI NAD-dependent deacetylase OS=Pedobacter kyungheensis GN=OC25_18755 PE=4 SV=1
----------------------------------------MKLVVLTGAGISAESGLKTFRDSDGLWEGYNVYDVATPEAWERNPDLVQEFYNERRRQVV
--AAQPNAAHRILAELEQ-DFD-VEIITQNIDDLHERAGSSKVTHLHGIITRSQSSLRPST--AGTEIKMGERCK-LGS--QLRPHVVWFGEAVPMIEVA
AKICEKADLFVLIGTSLAVYPAAGLIDFVPRQ-VNKYIIDPKTPDVK-QNVITIEQNAVNGMEQLRSILTNG-------
>tr|A0A0Q5TC30|A0A0Q5TC30_9SPHI NAD-dependent deacylase OS=Pedobacter sp. Leaf194 GN=ASG14_18540 PE=4 SV=1
----------------------------------------EKIVVLTGAGISAESGLKTFRDSDGLWEGYNIHDVATPEAWERNPELIQQFYNERREQVL
--SAKPNRGHEILGELEN-HFD-VEIITQNIDDLHERAGSTRVTHLHGIITKSQSDKNPNT--KGTEIKMGECCE-LGS--QLRPHVVWFGESVPMIELA
AEICKKADIFVLIGTSLAVYPAAGLLDFVPAA-VPKYVIDPVIPNIR-QNIIPIEKGAVNGITELLHVLVNG-------
>tr|A0A0Q4FUW4|A0A0Q4FUW4_9SPHI NAD-dependent deacylase OS=Pedobacter sp. Leaf216 GN=ASE74_09515 PE=4 SV=1
----------------------------------------MKLVVLTGAGISAESGLKTFRDADGLWEGYNVYDVATPEAWERNPILVQQFYNERRSQVL
--AAKPNHAHYLLAELEK-DFD-VEIITQNIDDLHERAGSTKVIHLHGVITKSQSDIKSEV--EGAEIKMGELCE-LGS--QLRPHVVWFGEAVPMIEVA
AKLCKQADIFVIIGTSLAVYPAAGLIDFVPSV-IDKYIIDPKTPDVK-KNVINIEKNAVEGVAELKEILSDAR------
>tr|A0A0Q5NEX5|A0A0Q5NEX5_9SPHI NAD-dependent deacylase OS=Pedobacter sp. Leaf176 GN=ASF92_16520 PE=4 SV=1
----------------------------------------MKLVVLTGAGISAESGLKTFRDSDGLWEGYNVYDVATPEAWERNPMLVQEFYNERRSQVL
--AAKPNRGHEILAELEK-YFD-VEIITQNIDDLHERAGSTKVTHLHGVITKSQSDIKADT--EGTEIKMGELCE-LGS--QLRPHVVWFGESVPMIEVA
SKICSKADVFVLIGTSLAVYPAAGLIDFVLPS-TPKYIIDPKTPDIR-KNTINIEKRAVDGVAELKEILLNGH------
>tr|A0A0Q4LX41|A0A0Q4LX41_9SPHI NAD-dependent deacylase OS=Pedobacter sp. Leaf41 GN=ASE92_05405 PE=4 SV=1
----------------------------------------MKIVVLTGAGISAESGLKTFRDADGLWEGYNVYDVATPEAWERNPELVQQFYNERRKQVI
--EAKPNRAHQLLAELEQ-DFD-IEIITQNIDDLHERAGSTKVHHLHGIITKSQSDLRENT--DGSDLKMGQLCE-LGS--QLRPHVVWFGEAVPMIEVA
ADICQQADIFVLIGTSLAVYPAAGLIDFVPAE-AIKYIIDPVTPNVK-RNVVKIEENAVQGVTQLKEILTNER------
>tr|A0A0J0Y9P1|A0A0J0Y9P1_9SPHI NAD-dependent deacetylase OS=Pedobacter sp. BMA GN=AB669_03020 PE=3 SV=1
----------------------------------------MKIVVLTGAGISAESGLKTFRDADGLWEGYNVYDVATPEAWERNPVLVQQFYNERRKQVI
--TAKPNRAHEILAELEA-HFD-VEIITQNIDDLHERAGSTKVTHLHGVITKSQSDRRADT--EGDEIKMGDLCE-LGT--QLRPHVVWFGEAVPMIEVA
AKICRQADLFVLIGTSLAVYPAAGLIDFIPSA-TKKYIIDPRTPDVG-KNVTTIQQSAVEGMSALKEILLNGR------
>tr|D7VRZ7|D7VRZ7_9SPHI Transcriptional regulator, Sir2 family OS=Sphingobacterium spiritivorum ATCC 33861 GN=cobB PE=3 SV=1
----------------------------------------KRIVVFTGAGISAESGLKTFRGDDGLWEGNRVEDVATPEAWQRNPALVQQFYNERRKQCL
--LAEPNTAHQALVRLEN-KYH-VDIITQNIDNLHERAGSKNILHLHGQIMQSRSSKDPYI--KGDELKMGDLCK-WGS--QLRPNIVWFGEAVPAMIPA
MRIAQQADILIVIGTSLQVYPAANLIHDIPPH-CEIFLIDPSADQYR-ERTVTITSKASEGVPALVEQLLSQI------
>tr|A0A0Q1F3D1|A0A0Q1F3D1_9SPHI NAD-dependent deacetylase OS=Pedobacter sp. Hv1 GN=AQF98_09980 PE=4 SV=1
----------------------------------------KRLVVLTGAGMSAESGIKTFRDADGLWEGYNVMEVATPEAWHANPVLVQQFYNERRKQVL
--QAEPNTAHFELAKLEE-HFD-VYIITQNIDDLHERAGSTQITHLHGIITYAQSDRNSNL--EGDELKMGELCE-LGS--QLRPHVVWFGEAVPEIETA
AAICATADVFMLVGTSLAVYPAAGLIDFVPVQ-TPKYIIDPKIPSVG-QNVIQIEKSATAGLKEVANLLRENG------
>tr|A0A0B8YDD1|A0A0B8YDD1_9SPHI NAD-dependent protein deacylase OS=Pedobacter glucosidilyticus GN=cobB PE=3 SV=1
----------------------------------------KKIIVLTGAGISAESGLKTFRDADGLWEGYAIEDVATPEAWQRNPALVQQFYNERRRSVL
--AAQPNAAHLALKKLEE-KFE-VLIITQNIDDLHERAGSSNMMHLHGEIVYARSSQNPAL--DKPDIEMGELCE-LGS--QLRPHVVWFGEAVPMITKA
MHEMPLADMVILIGSSLVVYPAAGLLELARKE-VPVYVIDPKIPQVN-NPLIKIEEKASLAVPLLVEKLLKHE------
>tr|A0A0C1LEB8|A0A0C1LEB8_9SPHI NAD-dependent deacetylase OS=Flavihumibacter solisilvae GN=OI18_15530 PE=3 SV=1
----------------------------------------KKLVVLTGAGISAESGLKTFRDSDGLWEGYDIEEVATPRAWKRDPALVLDFYNMRRKNVL
--AAEPNKAHQILASFQD-KFD-VHIITQNIDDLHERAGSYSVLHLHGEILKMRSDQDPAV---RSDMIYGALAP-DGH--AWRPDVVWFEEPVPRISQA
VPIVRSADIFLVVGTSLLVYPAAGLVDYAPHD-IPRYIVDKKIPYAG-SNLHAIEGPATEGMARLAEMLNKNDI-----
>tr|A0A0E3ZW65|A0A0E3ZW65_9BACT NAD-dependent deacetylase OS=Spirosoma radiotolerans GN=SD10_12005 PE=3 SV=1
----------------------------------------KKIVVLSGAGISAESGIPTFRASDGLWENHRIEDVATPEAWKRNPALVQDFYNQRRKQAL
--SVQPNAGHLALVKLED-KFD-VTVITQNVDNLHEKAGSSNVIHLHGELFKSRSSVDESI--EGWEIKAEDRCE-KGS--PLRPHIVWFGEAVPMMDIA
LEIADQADIFIVVGTSLNVYPAAGLVYVVRDG-VPVYVVDPNIPDMH-DNVTFIAEPATIGLTQLAEKLLAEAD-----
>tr|A6E870|A6E870_9SPHI NAD-dependent deacetylase OS=Pedobacter sp. BAL39 GN=PBAL39_01257 PE=4 SV=1
----------------------------------------KKMVVLTGAGISAESGLKTFRDADGLWEGYNVYDVATPEAWGRNPALVQTFYNERRKQVL
--EAEPNDAHRGIAKLES-QYE-VTVITQNIDDLHERGGSSSVIHLHGIITRSQSDLNPAT--EGWELRMGEYCE-LGS--QLRAHVVWFGEAVPMIEEA
ARICAEAEVFVLIGSSLAVYPAAGLIDFVPRH-CPKYIIDPRIPEVR-SGIIPIAENAVAGVRTLLKRLLPEGS-----
>tr|G8R2C7|G8R2C7_OWEHD NAD-dependent protein deacetylase, SIR2 family OS=Owenweeksia hongkongensis (strain DSM 17368 / JCM 12287 / NRRL B-23963) GN=Ow
----------------------------------------CRIVVLSGAGVSKESGLATFRENNGLWEEHDVYEVATPEAWNRDPEVVQRFYNARRKQLL
--EVFPNDAHKYLAKLEE-VFE-VVVVTQNVDDLHERGGSSNVVHLHGELRKSRSTLDESV--DGWEVTMEERCE-KGG--VLRPHVVWFGEMVPMIEAA
ASIVRSADLLLVVGTSLSVYPAAGLLHEASSD-VPVILIDPGELNTS-RNVHHIREKATVGVKNLVLKMLEYQK-----
>tr|A0A0M3G8I1|A0A0M3G8I1_HAEHA NAD-dependent deacetylase OS=Haemophilus haemolyticus GN=AAX18_06255 PE=3 SV=1
----------------------------------------PICVVLTGAGISAESGIPTFRAEDGLWAGHKIEEVCTPEALKKNRAKVLEFYNERRRNAQ
--VAEPNAAHLALVELEA-FYE-VHIITQNVDDLHERAGSTNVLHLHGELNKARSSFNTDI---LGDQLLEDKDN-HGH--PMRPHIVFFGENVPMFPKA
EKLVKKADIVIVIGTSLQVYPANGLVNLAPYG-SLIYLIDPNPNTGF-RKVIAIKEKAGEGVPKVVAELLEKIK-----
>tr|C4GLT0|C4GLT0_9NEIS NAD-dependent deacetylase OS=Kingella oralis ATCC 51147 GN=npdA PE=3 SV=1
----------------------------------------PTIAILTGAGISAESGLATFRDSNGLWANHRIEDVCTLEAWERNPQLVLDFYNQRRAQAA
--AAQPNAAHIALAQLQQ-HFP-VHIITQNVDDLHERAGSHNVLHLHGQLNQARSSADPDI--TQD-QTLQDKDP-HGN--PMRPHIVWFGESVPLLDEA
AAIVRQADVFLIIGTSLQVYPANTLAYYARPD-ARIIVLDPHPQNTQ-AQVEIIRQTAAAGVPVLCQHLIECYT-----
>tr|A0A066TV04|A0A066TV04_9NEIS NAD-dependent protein deacetylase of SIR2 family OS=Snodgrassella alvi GN=SALWKB12_0418 PE=4 SV=1
----------------------------------------QQVVVLTGSGISAESGLKTFRNHGGLWDGERVEDVATPEGFARNPLRVLDFYNRLRRQLQ
--NVQPNAAHLALRHLES-SYE-VNIITQNVDDLHERAGSSHVLHLHGELLKARSSVDENI--FSD-QTMADVDA-RGF--PMRPHIVWFGEAVPMIEAA
IQLMQTADIVIIIGTSLQVYPAAGLVQYIPPD-AEVFLVDPQPYEG--QNVQFIRASAQAGVSSLVSELLQRSE-----
>tr|A0A080JZS4|A0A080JZS4_9NEIS NAD-dependent protein deacetylase, SIR2 family OS=Snodgrassella alvi SCGC AB-598-O02 GN=SASC598O02_005080 PE=3 SV=1
----------------------------------------QKVVVLTGSGISAESGLQTFRDHGGLWAGHRVEDVATPEAFDRHPQQVLDFYNQLRRQMQ
--TAQPNAAHKALVRLEE-FYQ-VNIITQNVDDLHERAGSSNVLHLHGELLKARSSVDEYIVDCFADQTLADVDV-NGN--AMRPFIVWFGEAVPLLDEA
IELTRQADILIVIGTSLQVYPAASLLQFVPVN-AEVFLVDPKPPQNL-NSVQIIRANAQSGVTSLVQSLIERKN-----
>tr|A0A074V3Z0|A0A074V3Z0_9NEIS NAD-dependent protein deacetylase, SIR2 family OS=Snodgrassella alvi SCGC AB-598-J21 GN=SASC598J21_020410 PE=4 SV=1
----------------------------------------QHIVVLTGSGISAESGLQTFRNQGGLWEGERVEDVATPEAFKRQPLYVLNFYNQLRRQLL
--KTEPNSAHVALKRLED-GYD-VDIITQNIDDLHERAGSPHVLHLHGELLKARSCVDENI--LGD-QNVTDVDV-NGF--PMRPHIVWFGEAVPMIEQA
IHVMRSADIAIIIGTSLQVYPAAGLIQYIPPN-AEIYLVDPQPIDG--QNVQIIRAPAQAGVSSLVNELLQRPE-----
>tr|L1MLL8|L1MLL8_9BACT NAD-dependent deacetylase OS=Prevotella sp. oral taxon 473 str. F0040 GN=HMPREF9999_00894 PE=3 SV=1
----------------------------------------RKLVVLTGAGMSAESGFATFRDSGGLWETHPVERVATPEGWAADPDYVNGFYNGLRRQLV
--TAHPNRGHELLAALEQ-DWD-VTIVTQNVDDLHERAGSSRVVHLHGELMKVTSSRNPEI-SPNLEIAPGQCAT-DGS--LLRPYIVWFGEAVPMIEVA
AEIVAQADVFVIVGTSLMVYPAAGLVHYARKD-IPIYLIDPNEVNVP-SHLTFIQQGASEGIAHLCTLLAAHS------
>tr|R7LEJ9|R7LEJ9_9BACT Transcriptional regulator Sir2 family OS=Prevotella sp. CAG:891 GN=BN805_01722 PE=3 SV=1
----------------------------------------QKLVVLTGAGMSAESGFSTFRDAGGLWEQYPVEQVATPEGWQANPNLVTDFYNGLREQLV
--AARPNRGHELLAELEQ-HFD-VTVVTQNVDDLHERAGSSHVIHLHGELMKVCSSANPDI-PDHLRVAHGELAA-DGS--LLRPWIVWFGEAVPNLVPA
ADITAQADIFVIVGSSLQVYPAAGLIRYTRPG-IPIYLIDPQPVQVP-HYIEVISQKASEGMATLVSRLLPSV------
>tr|J9H4I0|J9H4I0_9ZZZZ Transcriptional regulator, Sir2 family OS=gut metagenome GN=EVA_03188 PE=4 SV=1
----------------------------------------KKLVVLTGAGMSAESGFSTFRDAGGLWEQYPVEKVATPEGWEENPKLVTDFYNGLRQQLV
--KAKPNRGHELLAEMER-DYD-ITIVTQNVDDLHERAGSSKVIHLHGELMKVCSSAHPDI-TDHLTVADGQRAA-DGS--LLRPWIVWFGEAVPNLVPA
AEVTAQADIFCIIGSSLNVYPAAGLVSYTKPG-TPVFVIDPKEVHVP-SRIEIIQEVASKGVQELWERLQTLER-----
>tr|B5IHC4|B5IHC4_ACIB4 Transcriptional regulator, Sir2 family OS=Aciduliprofundum boonei (strain DSM 19572 / T469) GN=ABOONEI_235 PE=3 SV=1
----------------------------------------KRIVALTGAGISAESGIPTFRGTGGLWEGYPVEKVATIEGFERDPALVWKFYDERRRNIA
--KARPNRAHEVLALFENLY--DFWVITQNIDGLHSRAGSKNVVELHGNIWRVKCTECGIV-----LREI-PKCKRCGG--LLRPDVVWFGEPVYD--KA
YELTESCDVMLVIGTSAQVYPAAYLPRLAWSKGAKIIEINPQ---------FVIREKATKALDELYRGLLRAFQ-----
>tr|A1ZZG3|A1ZZG3_9BACT NAD-dependent deacetylase OS=Microscilla marina ATCC 23134 GN=M23134_00983 PE=3 SV=1
----------------------------------------QKIVVLTGAGISAESGISTFRDSDGLWENHDVMEVASPEGWQKDRALVLEFYNQRRTHAL
--AAQPNEGHLALARLEA-KYE-VVIITQNIDDLHEKAGSSNVLHLHGELGKARSTTNPEV---NKPINIGDKCE-KGS--QLRPHIVWFGEAVPMMTVA
IQETHSANLFIVVGTSLAVYPAAGLLDEVDTD-VPKYIIDPRMPDVRRPHLHLIEEKGSVGVPTLVDKLLAKVS-----
>tr|Q6AIJ8|Q6AIJ8_DESPS Uncharacterized protein OS=Desulfotalea psychrophila (strain LSv54 / DSM 12343) GN=DP3103 PE=4 SV=1
----------------------------------------KRLVVLTGAGMSAESGFATFRDSGGLWENYDVMEVASPEGWVRDKGLVNQFYNERRVQLR
--DSVPNGGHLALAQLEE-RFE-VHIVTQNVDDLHERAGSSRVLHLHGELTKVESCSNSAV-Y--RQVGLEERAE-DGG--QLRPHIVWFGEAVPAIEEA
VNICLTADIFVIIGTSLAVYPAASLTEYVKAG-APIYLVDPHKPKIN-LDYHFINKRATAGIQELISLLV---------
>tr|A3HRU1|A3HRU1_9BACT NAD-dependent deacetylase OS=Algoriphagus machipongonensis GN=ALPR1_10100 PE=3 SV=1
----------------------------------------KKFVVLSGAGISQESGIKTFRDSNGLWENHDIMEVASPQGWNKNRALVQEFYNLRRKQAQ
--ECQPNTAHIKLAQLED-KFD-ITIITQNVDDLHERAGSSKVIHLHGELNKAQSSFNPDV--DHWEIKEGQLCE-LGS--QLRPHIVWFGEMVPKMSDA
IEEAAKADIFLVIGTSLQVYPAASIIEYVPST-AKKFLIDLQIPDYK-PSVICIEKKASDGMKELENVILEE-------
>tr|A0A0D5YP70|A0A0D5YP70_9FLAO NAD-dependent protein deacylase OS=Muricauda lutaonensis GN=VC82_47 PE=3 SV=1
----------------------------------------RRIVVLTGAGMSAESGLKTFRDADGLWEGHDVMQVASPQGFATDPELVLEFYNQRRRQLL
--EVEPNAGHTALVKLEE-KFD-VQIITQNIDNLHEKAGSTNVLHLHGELLKVRSTVNHDVMDWTKDLHLGDVGD-DGH--QLRPHIVWFGEMVPMLEPA
IEITQTADILIIIGTSMQVYPAASLINYAANS-VPIYFIDPRPTIGRYSNLTVMADTAAKGVPKLVNRLIDSAP-----
>tr|E4TPX0|E4TPX0_MARTH Silent information regulator protein Sir2 OS=Marivirga tractuosa (strain ATCC 23168 / DSM 4126 / NBRC 15989 / NCIMB 1408 / VKM 
----------------------------------------KKLVVLTGAGISAESGIPTFRGADGLWEGHDVIEVASPQGWAQNQSLVLDFYNQRRKAVL
--EAEPNAAHKILAELED-YYD-VQVITQNIDDLHERGGSSNVLHLHGEIKKARSSVDETI---GWEIKEGDLCE-KGS--QLRPHIVWFGEMVPMIEPA
ARITASADVLLVVGTSLQVYPAAGLIHEVGKD-VPIYVVDPSTPEYYSNQVTAIAKSAVEGMKQLKEILV---------
>tr|A0A0P7B4P8|A0A0P7B4P8_9FLAO NAD-dependent deacetylase OS=Croceitalea dokdonensis DOKDO 023 GN=I595_647 PE=4 SV=1
----------------------------------------KKIVVLTGAGMSAESGLKTFRDANGLWEGHDVMQVASPEGFANDPELVLEFYNQRRRQLL
--EVAPNKGHHDLAAMET-DFD-VHIITQNVDNLHEQAGSSKVLHLHGELLKVRSTENENIRYWEKDLIVGDVDQ-NGH--QLRPHIVWFGEMVPQLDNA
IAITKKAEVLLIIGTSMQVYPAASLIHYVRMG-TPIYFIDPKSKVGAFPNLQIISKTASEGVSEVIRMLQKT-------
>tr|A4AQ52|A4AQ52_MARSH Uncharacterized protein OS=Maribacter sp. (strain HTCC2170 / KCCM 42371) GN=FB2170_13723 PE=3 SV=1
----------------------------------------KNIVVLTGAGISAESGIKTFRDADGLWEGHDVMQVASPQGFANDPELVLDFYNQRRRQLL
--EVSANKAHNALVELET-RHT-VTIITQNVDDLHERAGSKNVVHLHGELLKVRSTSD-NTTTWRKDLNLGDLCQ-NGH--QLRPHIVWFGEDVPMMTRA
IEITCKADILIIIGTSMQVYPAASLIDFVEPE-TPIYFIDPKPSLQGRKNIEVIPENATLGVPTLVADLIGKEL-----
>tr|F0RG17|F0RG17_CELLC NAD-dependent deacetylase OS=Cellulophaga lytica (strain ATCC 23178 / DSM 7489 / JCM 8516 / NBRC 14961 / NCIMB 1423 / VKM B-143
----------------------------------------KNIVLLTGAGISAESGIKTFRDADGLWEGHDVMQVASPQGFAADPELVLDFYNQRRKQLL
--TVKPNKAHLAITKLQE-HFN-VTVITQNVDDLHERAGNKNVVHLHGELLKARCTQNETVLEWTKDLNLGDLSK-SKN--QLRPHIVWFGEEVPLLEKA
AKITETADVLIIIGTSMQVYPAASLVHYVTNG-TPIYFIDPNPSIKQFNNLTIINKTAVNGLPTLVKDLIDTML-----
>tr|A0A0B5RLN7|A0A0B5RLN7_9FLAO NAD-dependent deacetylase OS=Myroides profundi GN=MPR_2549 PE=3 SV=1
----------------------------------------KKLVVLSGAGMSAESGIKTFRDADGLWEGHDVMQVASPQGWQQNKELVLQFYNNRRRQLL
--SCQPNKAHYILAQLEQ-YYN-VSIITQNVDDLHERAGSNNIIHLHGELLKVRSEQNEKIYPWSKDLLTDDSNE-FGH--SLRPHIVWFGEMVPELEKA
IPLVEAADIIIIIGTSMQVYPAASLISYARSD-AQAYYIDTNPALVQPCELTVLKNTASEGLNSILNELIKKAQ-----
>tr|G2PQX1|G2PQX1_MURRD NAD-dependent deacetylase OS=Muricauda ruestringensis (strain DSM 13258 / LMG 19739 / B1) GN=Murru_0045 PE=3 SV=1
----------------------------------------PKIVVLTGAGMSAESGLKTFRDENGLWEGHDVMEVASPQGFARNPELVLEFYNQRRRQLL
--EVIPNAGHKALAELEQ-DFD-VSIVTQNVDNLHEKAGSSYVVHLHGELFKVRSTVNENVLDWKKDLVLGDTDD-KGH--QLRPHIVWFGEMVPMLETA
AQITQQAEILIIVGTSMQVYPAASLIHYAPNK-TPIYFIDPKPNIRSFENLTVIPKTAAEGIPELVEKFFNSWP-----
>tr|A0A0Q0XJ76|A0A0Q0XJ76_9FLAO NAD-dependent deacetylase OS=Flagellimonas sp. DK169 GN=AAY42_02105 PE=4 SV=1
----------------------------------------QKIVVLTGAGMSAESGINTFRDSDGLWEGHDVMEVASPQGFAKNPELVLDFYNQRRRQLL
--EVSPNAGHKALVDLEK-WFD-VNIVTQNVDNLHEQAGSSRVVHLHGELFKVRSTANENVLTWKKDLILGDLDE-NGH--QLRPHIVWFGEMVPMLKPA
IDITLNADILIIIGTSMQVYPAASLINYVSDQ-VPIYFVDPKPSVAKFKNLTVIPKTAVNGVPNLVAELSDMVT-----
>tr|A0A068NQ54|A0A068NQ54_9BACT NAD-dependent protein deacetylase of SIR2 family OS=Fimbriimonas ginsengisoli Gsoil 348 GN=OP10G_2315 PE=4 SV=1
----------------------------------------MKIVVFTGAGVSRESGLLTFRDEDGLWNGYSIHEVASMKGWWADPAKVLDFYNMRRREAR
--QAEPNDAHRAIAELEKDH--DVTVITQNVDDLHERAGSTNVIHLHGELFKVRAIDEEET---V-DLVL-DVHPEKGT--QLRPHVVWFGEGLPELDMK
IALDPGVDVLIVVGTTLTVYPAALIA-TETNAW-HVFVVDPN----------YIREPATYGMKLVTEAIKALPL-----
>tr|R9GPV2|R9GPV2_9SPHI NAD-dependent protein deacetylase of SIR2 family OS=Arcticibacter svalbardensis MN12-7 GN=ADIARSV_3009 PE=3 SV=1
----------------------------------------KKLVILTGAGISAESGLKTFRDSDGLWEGYNVEEVCTADAWRRNPVLVQTFYNDRRKAII
--DAWPNAAHIALARLQE-KYD-VQIITQNIDDLHERAGSKSVTHLHGLITRSQSSLNSAT--DGWEIKMGDVGE-DGS--QLRPHVVFFGEAVPMLEKA
IEICAQADIFAVIGTSLVVYPAAGLVDYVPKG-IVKYIVDPNVPLGK-KGFIVIQEKATVGVVEMVRELMGEIT-----
>tr|A0A0E9N8C1|A0A0E9N8C1_9SPHI NAD-dependent protein deacylase OS=Flavihumibacter petaseus NBRC 106054 GN=cobB PE=4 SV=1
----------------------------------------KRLVVLTGAGISAESGLKTFRDSDGLWEGYAIEDVATPRAWGKNPELVLSFYNERRRNVL
--GASPNAAHIGLAALEE-FFE-VQIITQNIDDLHERGGSSSVLHLHGEIFGRKSDRDGWK---TGDMLPGDLAP-DGG--VWRPDIVWFEEPVPLIIEA
AEIVRAADIFVVVGTSLVVYPAAGLVDYVQPD-VTVYVVDRKLPLIS-PGVRSIEAPATEGVAKLKELLLADLF-----
>tr|I4AFA0|I4AFA0_FLELS NAD-dependent protein deacetylase, SIR2 family OS=Flexibacter litoralis (strain ATCC 23117 / DSM 6794 / NBRC 15988 / NCIMB 1366
----------------------------------------KKIVVLTGAGVSAESGIATFRASDGLWEGHRVEEVASPKGWEQDPEKVLKFYNERRKGVL
--EAVPNEAHKILAQLER-NFD-VTIITQNVDDLHERAGSTHVLHLHGELMKARSSVDESV--DGWELKMGEKCP-KGH--QMRPYIVWFGEAVPMMEQA
MMEAMGADIFVVVGTSLLVYPAAGLLDYAPRQ-TPKYIIDPKSPAVR-PNLHFIEEVATTGMKKLEAMLMRDYT-----
>tr|D1PTM8|D1PTM8_9BACT Transcriptional regulator, Sir2 family OS=Prevotella bergensis DSM 17361 GN=cobB PE=4 SV=1
----------------------------------------KKVVFLTGAGMSVESGFKTFRGNDGLWENYPVEQVASHEGWLADPTLVTNFYNMLRRKLW
--DAQPNEGHRLIAELQN-DYD-VSVLTQNVDDLHERAGSQKVIHLHGELSKACSSDDPYI-PKHSDVEPGTRAD-DGS--LLRPFIVFFGESVPMLEPA
SYEAQQADIFVIIGTSLNVYPAAGLVRYTKPG-CPIYLIDPNAVSID-MPLTHIQKGASAGMSELVKLLRE--------
>tr|F8N657|F8N657_9BACT NAD-dependent deacetylase OS=Prevotella multisaccharivorax DSM 17128 GN=Premu_0665 PE=4 SV=1
----------------------------------------KKVVFLTGAGMSVESGFKTFRGNDGLWENYPVEQIASHEGWERDPRLVTEFYNRLRRKLW
--DAQPCEGHRLIAEMEK-DYD-VTVLTQNVDNLHEKAGSTRVIHLHGELTKACSSNDPYI-PDNSDVEPGTKAG-DGS--LLRPFIVFFGESVPMLEPA
AEAASHADIFVIIGTSLVVYPAAGLMQFVPRD-SPVYLIDPNPVAAG--GVTQIQKGASEGMKELLKRI----------
>tr|D8DZT2|D8DZT2_PREBR Transcriptional regulator, Sir2 family OS=Prevotella bryantii B14 GN=cobB PE=4 SV=1
----------------------------------------KKIVFLTGAGMSVESGFKTFRGNDGLWENYPVEQVASHEGWEANPTLVTNFYNMLRKKLW
--SALPNEGHKLIQQLEK-DYE-VSVITQNVDNLHEKAGSSHVIHLHGELTKVCSSDDPYI-EEHSDVEPGTRAA-DGS--LLRPFIVFFGESVPMIEPA
IEEAQKADIFVVIGTSLNVYPAAGLVQYTHRG-TPIYLIDPNPVITE-RLIKQILKGASEGMRDLVSILSE--------
>tr|F9D369|F9D369_PREDD NAD-dependent deacetylase OS=Prevotella dentalis (strain ATCC 49559 / DSM 3688 / JCM 13448 / NCTC 12043 / ES 2772) GN=cobB PE=4
----------------------------------------KKIVFLTGAGMSVESGFKTFRGNDGLWENYPVEQIASHEGWEANPTLVTEFYNKMRRKLW
--DAEPNEGHRLIAGMEK-DYE-VSVLTQNVDNLHERAGSTNVIHLHGELTKVCSSADPYI-QADSDVAPGSTAG-DGS--LLRPFIVFFGESVPMLEPA
AREATGADAFVIIGTSLNVYPAAGLVQYTRRD-CPVYLIDPNPVSAG-GRVTHIRKGASEGMAELLRLLSQ--------
>tr|U2KR71|U2KR71_9BACT Transcriptional regulator, Sir2 family OS=Prevotella pleuritidis F0068 GN=HMPREF1218_0978 PE=4 SV=1
----------------------------------------KKIVFLTGAGMSVESGFKTFRGSDGLWENYPVEQVASHEGWENDPTLVTNFYNMLRRKLF
--DAQPNEGHKLIADLEK-DYN-VTVVTQNVDNLHERAGSSKVVHLHGELTKVCSERDPYI-ADNPEVNPGTQAG-DGS--LLRPFIVFFGESVPMIEPA
ATEISTADIFVIIGTSLNVYPAAGLVRYVRSG-TPIYIIDPEPVTAD-NSIVHIAKGASAGMQALTKSLRSLN------
>tr|A0A095ZGT1|A0A095ZGT1_9BACT NAD-dependent protein deacylase OS=Prevotella sp. S7-1-8 GN=HMPREF1640_05880 PE=4 SV=1
----------------------------------------KKIVFLTGAGMSVESGFKTFRGNDGLWENYPVRQVASHEGWLADPTLVTNFYNMLRKKLW
--NAQPNEGHRLIAELEK-DYE-VAVLTQNVDDLHERAGSSKVIHLHGELSKACSADDPYI-PENSEIKPGTKAG-DGS--LLRPFIVFFGESVPMLEPA
AREAMTADIFVIIGTSLIVYPAAGLVNYTKRQ-CPIYLIDPDDMDNY-MPLTHIQKGASEGMREFIDLLKQNKL-----
>tr|E0NPR5|E0NPR5_9BACT Transcriptional regulator, Sir2 family OS=Prevotella marshii DSM 16973 = JCM 13450 GN=cobB PE=3 SV=1
----------------------------------------KKIVVLTGAGMSAESGLSTFRDADGLWENYPVMQVASHEGWLADPELINTFYNRLRQQLV
--HAKPNEGHRLVAKLEE-KYN-VTVVTQNVDNLHERAGSTHVIHLHGELMKACSGDDAYI-EDNPVIVPGSKTK-DGA--LKRPFIVFFGEAVPMIETA
VFEVETADMMIIIGTSLNVYPAAGLVRYLRKG-APVYVIDPKPVSSS-ISATMIRKGASEGMRELSAQLMK--------
>tr|U2L8G4|U2L8G4_PORGN Putative NAD-dependent deacetylase OS=Porphyromonas gingivalis F0566 GN=HMPREF1989_01585 PE=3 SV=1
----------------------------------------KRLVVLSGAGMSAESGISTFRDANGLWENYPVEDVASIDGFRRNPALVLKFYNARRRDYA
--GCKPNAGHIGLAEMEK-EYD-VRIITQNVDDLHERAGSTRVIHLHGELMKNRSVATDSL-PTNPDLHVGDLAP-DGC--QLRPFIVWFGEAVPMIEPA
IEEVTQADILVVIGTSLNVYPAAGLLNYAPRN-CPIYLIDPKPVRST-QDIRYIHAPATEGVRMLRQELRDIDR-----
>tr|C3J921|C3J921_POREA Transcriptional regulator, Sir2 family OS=Porphyromonas endodontalis (strain ATCC 35406 / BCRC 14492 / JCM 8526 / HG 370) GN=co
----------------------------------------KRLVVLTGAGMSAESGISTFRDSDGLWEQYPVQKVASIEGFRENPQLVLDFYTARRRDFV
--GCKPNAGHYALAALQE-EWE-MTIITQNIDDLHERAGSRHVIHLHGEILKNCSVAHPDT-MEHPEIKVGDLAP-DGS--QLRPFIVWFGEAVPMIAPA
AEAVCQADCFVVIGTSLNVYPAAGLLAYVPHA-TPIYLIDPKPVESS-KDIVFIQSTASEGVAKLAALLSK--------
>tr|R7HMZ5|R7HMZ5_9BACT Uncharacterized protein OS=Prevotella sp. CAG:279 GN=BN585_01991 PE=4 SV=1
----------------------------------------KKLVVLTGAGISAESGLSTFRDADGLWNNYPVMDVASHDGFVRNPALIHSFYNGLRRQLL
--DKKPNAAHLGLKELEK-DFD-VRIITQNVDDLHERAGSSHVLHLHGELMKVRSMTHEEV-PDNIETSVDTRDE-YGD--PVRPHIVFFQEAVPNFDTA
VKIAQEADIFVVIGTSLNVYPAAGLLFYAPKN-APIYYIDPRPAAIPVGNVTVIAEPATAGVRELIKKLKNQ-------
>tr|T1DQZ5|T1DQZ5_9PORP NAD-dependent protein deacetylase of SIR2 family OS=Porphyromonas crevioricanis JCM 15906 GN=PORCRE_304 PE=3 SV=1
----------------------------------------ARLVVLTGAGMSAESGISTFRDSNGLWENHRVEDVASIEGFERNPELVLDFYNARRRAYK
--GCDPNEGHRILAQLEE-QYE-VKIITQNVDDLHERAGSSSVIHLHGELMKNRSVRTDRL-LDNPDLHVGDLAP-DGS--QLRPFIVWFGEPVPMIEPA
IQLAQTADIFVVVGTSLVVYPAAGLLNYVPRG-CPIYLIDPQPVAAT-AGVQHIQAKATTGLAQLRAVLLNRQ------
>tr|F4KKJ9|F4KKJ9_PORAD NAD-dependent deacetylase OS=Porphyromonas asaccharolytica (strain ATCC 25260 / DSM 20707 / VPI 4198) GN=Poras_0981 PE=3 SV=1
----------------------------------------RKLVILTGAGVSAESGISTFRDSDGLWENYPVQDVASIEGFIRNPKLVLDFYNARRRDYV
--GCEPNAAHYGLAELER-QYD-VTVVTQNVDNLHERAGSSKVIHLHGELMKNCSVRNTQT-PKHPDLHVGDLAP-DGS--QLRPFIVWFGEAVPMIEPA
IREASQADIMVVVGTSLNVYPAASLLAYVPNG-TPIYLIDPKEVNTH-AHVTHIQKVATQGVQELLEILMPES------
>tr|A0A087N1C2|A0A087N1C2_9BACI NAD-dependent protein deacetylase OS=Lysinibacillus sp. BF-4 GN=cobB PE=3 SV=1
----------------------------------------KSVVVFTGAGMSTESGLPDFRS-DGLWQQTNPQRIASVAALNDNVEQFFEFYRTRVQGVT
--GCEPHKGHHILAKWQAEGIID-TIITQNVDGFHTAANSSDVLELHGTLRTVHCQSCQKM-----RAY----C-TCG-G-TLRPSVVLFGEMLDHSVQS
VKQSESADVFIVLGSSLSVSPANQFPLLAYKHGATLVIINEEETPYD-LAALVVRNKIGDFLVRIDNELHS--------
>tr|W3AFA9|W3AFA9_9BACL NAD-dependent protein deacetylase OS=Planomicrobium glaciei CHR43 GN=cobB PE=3 SV=1
----------------------------------------NHTVVFTGAGMSTESGLPDFRSNQGLWQQKDPSQVASVSALNNNVEEFIEFYRKRVIGVN
--EYHPHRGHQLLAEWEDRGLIQ-AIITQNVDGFHQQAGSKQVAELHGTLQKVHCNSCGTE-----GTY----CIACG-G-LLRPSVVLFGEMLPEEARA
FEEAARAELFIVLGSSLTVTPANQFPLIAKENGARLVIVNQEETPLD-YADEVIHDKIGEVLAEWAGMLK---------
>tr|A0A0F5I490|A0A0F5I490_9BACI NAD-dependent protein deacetylase OS=Bacillaceae bacterium MTCC 8252 GN=cobB PE=3 SV=1
----------------------------------------NYTVIFTGAGMSTESGLPDFRSNQGLWNQKNPEKIASTDALNNNIQEFIDFYRNRVLGVK
--EFKPHKGHDLLAEWEKKGIIQ-SIITQNVDGFHQQAGSQKVAELHGTLQTVFCQSCGRE-----RTY----C-TCG-G-VLRPSVVLFGEALPEEPMA
FEEASKAELFIVLGSSLSVTPANQFPLIAKENGAKLVIVNREPTDLD-YADETIHNNIGEVLRDWNAYFS---------
>tr|A0A0A1MBY1|A0A0A1MBY1_9BACI NAD-dependent protein deacetylase OS=Oceanobacillus oncorhynchi GN=cobB PE=3 SV=1
----------------------------------------KHTVVFTGAGMSTESGLPDFRSNRGLWRKKDPSKIASVDALNHHVEDFIEFYRERVLGVK
--EVGPHKGHHILADWENNGLIQ-SIITQNVDGFHQAAGSRHVHELHGTLQELHCQSCGKA-----EDY----C-SCG-G-ILRPSIVLFGEMLPEDAAA
FEHAKKADLFIVLGSSLSVTPANQFPEIAKQSGAKLVIVNQEKTPLD-FADEVVFDKIGAYLEETDQLLYNR-------
>tr|A0A0P7IQT5|A0A0P7IQT5_9BACI NAD-dependent deacetylase OS=Lentibacillus amyloliquefaciens GN=AOX59_10795 PE=4 SV=1
----------------------------------------SHTVVFTGAGMSTESGLPDFRSNQGLWKQKDPSKIASTDALNSNVDEFIEFYRSRVLTVK
--DYKPHKGHHILADWEKEGIIH-SIITQNVDGFHQAAGSQNVSELHGTLTKVHCQSCGRA-----QTY----C-ECG-G-ILRPSITLFGEMLPQDALA
QSESEQADLFIVLGSSLSVTPANQFPLIAKDNGARLVIVNREPTEFD-FADEVIHSEIGEVLEEWNH------------
>tr|A0A0L0QT31|A0A0L0QT31_VIRPA NAD-dependent protein deacetylase OS=Virgibacillus pantothenticus GN=cobB PE=3 SV=1
----------------------------------------KYTVVFTGAGMSTESGLPDFRSNKGLWKQKDPSKIASTDALNSNVEAFIEFYRERVLGVK
--TYQPHKGHYILAEWEKQGRIK-SIITQNVDGFHQQAGSQRVAELHGTLQKLHCQSCGKE-----KDY----C-SCQ-G-ILRPSIVLFGETLPMDAFA
LAEAEKADLFIVLGSSLSVTPANQFPLIAKEHGAKLVIVNREPTELD-YADELIHGSIGEVLKEVNE------------
>tr|A0A075JTP8|A0A075JTP8_9BACI NAD-dependent protein deacetylase OS=Virgibacillus sp. SK37 GN=cobB PE=3 SV=1
----------------------------------------NYTVVFTGAGMSTESGLPDFRSNQGLWNKKDPSKIASTDALNNNVNDFISFYRERVLGVK
--EYSPHKGHYILADLEKQGYVK-SIITQNVDGFHQQAGSKNVAELHGTLQTVHCQSCGEE-----KEY----C-TCG-G-ILRPSIILFGETLPQDAFA
LEESRKSDLFIVLGSSLSVTPANQFPLIAKEMGAKLVIINREKTPFD-YADQVIRDAIGKVLAELDM------------
>sp|Q8ELR0|NPD_OCEIH NAD-dependent protein deacetylase OS=Oceanobacillus iheyensis (strain DSM 14371 / JCM 11309 / KCTC 3954 / HTE831) GN=cobB PE=3 
----------------------------------------NYTVIFTGAGMSTESGLPDFRSNTGLWKQHDPSKIASIDTLNNNVETFIDFYRERVLKVK
--EYGPHQGHYILAEWEKQGLVH-SIVTQNVDGFHQASGSKIVHELHGTLQKLHCQSCGKE-----NEY----C-DCG-G-VLRPSIILFGEMLPQEATA
FNDAEKADLFVVLGSSLTVSPANQIPLIAKENGAKLVIVNQDPTPYD-YADMTISDKIGEFLRSISNEG----------
>tr|A0A090J171|A0A090J171_9BACI NAD-dependent protein deacetylase OS=Bacillus thermoamylovorans GN=cobB3 PE=3 SV=1
----------------------------------------QYTVVFTGAGMSTESGLPDFRSNNGLWRKNNSSQIASTKALNENVKEFTAFYRERVLGVK
--EFGPHKGHYILAKWEQQGIIR-SIITQNVDGFHQEAGSTRVAELHGTLQKLHCQKCGRN-----KDY----C-ECG-G-VLRPNIVLFGEVLPQDALA
MEETEKADLFIVLGSSLTVTPANQFPLIAKGSGAKLVIVNMEPTPYD-FADQVIHDKIGEILTELDQKIQ---------
>tr|A0A0K0G6T1|A0A0K0G6T1_9FIRM NAD-dependent protein deacetylase OS=Bacilli bacterium VT-13-104 GN=cobB PE=3 SV=1
----------------------------------------KNMVVFTGAGMSTESGLPDFRSNNGLWRKKDPSKIASTEALNDNVDEFIDFYRERVLKVK
--EFNPHKGHYILADWEEKGKLQ-SIITQNVDGFHQLAGSKRVAELHGSLQHLRCQSCGKE-----KEY----C-SCG-G-ILRPNIVLFGEMLPQDAFA
EEEAIKSDLFIVLGSSLSVTPANQFPLIAKEHGAKLVIVNQEKTELD-YADQVIQDKIGELLQELDKELFS--------
>tr|I4X5W4|I4X5W4_9BACL NAD-dependent protein deacetylase OS=Planococcus antarcticus DSM 14505 GN=cobB PE=3 SV=1
----------------------------------------KHMVVFTGAGMSTESGLPDFRSNTGLWQQKDPSQVASVKALNTNVEEFIEFYRKRVLGVK
--EFEPHNGHRILTEWENDGRLQ-SIITQNVDGFHQLAGNRNVAELHGTLQKVHCQSCGTE-----ESY----C-ECS-G-LLRPSVVLFGEMLPEEPIA
FNEAIRADLFIVLGSSLSVTPANQFPLIAKENGSKLVIVNQEATPFD-YADLVINNQFGDVLSEWHRFWTD--------
>tr|R9CII2|R9CII2_9BACI NAD-dependent protein deacetylase OS=Bacillus nealsonii AAU1 GN=cobB PE=3 SV=1
----------------------------------------NYLVVFTGAGMSTESGLPDFRSNTGLWTAEKKQYLSSTDALNNHVQEFINFYRQRVQGIH
--EFKPHQGHYILSEWERNGLLK-QIITQNVDGFHQEAGNENVAELHGTLKKIHCETCGKE-----ENY----C-DCG-G-VLRPSIVLFGEMLPEQPTA
EEAAIKSDVFLVLGSSLSVSPANQFPLMAKQTGAKLIIVNKEPTEMD-LADLVIHQSIGKVLEDINFKLT---------
>tr|A0A0J6D405|A0A0J6D405_9BACI NAD-dependent deacetylase OS=Anaerobacillus macyae GN=AB986_07280 PE=4 SV=1
----------------------------------------KHTVVLTGAGMSTESGLPDFRSIDGMWNEVDPLQFASRDAMQFERDLFVRFYKQRIQKLK
--GARPHAGYYHLAEWERTGEVG-FILTQNVDGFHQQAGSQNVAELHGTLCDIYCDECGDG-----DEI----C-VCG-G-FKRPGVVLFGEPLPLSAQA
KMETKKADLFIVLGSSLQVSPANVFPMEAKRNGAKLVIVNQEATEYD-YADLVINDKIGSVLDELVQSNNYKS------
>tr|A0A0Q0R5Z9|A0A0Q0R5Z9_BACTU Uncharacterized protein OS=Bacillus thuringiensis GN=AL712_30490 PE=4 SV=1
----------------------------------------NHIVVLTGAGISTDSGLPDYRS-GGLWDGKKPEEISHFSAVG--KPEFVKFFADRMNDIS
--NCKPNKAHEILAKWEEQGKVK-SVITQNIDSYHKDAGSKNVIEMHGHLRNLVCDTCSKM--DKD------NCGLCT-G-VVRPEVVLFGETLPPLAQA
NEQMKKTDLVIVLGTSLQVFPFNSLVESVYP-GAPVMIITKSDTPYD-MASVRIYDNITETLVEIDNRLK---------
>tr|A0A0M1QN54|A0A0M1QN54_GEOTC NAD-dependent protein deacetylase OS=Geobacillus thermoglucosidasius (strain C56-YS93) GN=cobB PE=3 SV=1
----------------------------------------RHAVVLTGAGMSTESGLPDFRSKTGLWNRFNPQQLASTYALEHQRQSFVEFYQYRIRTLR
--SCKPHEGHAILADWEQRGWIK-QIITQNVDGFHQQAGSRHVIELHGSLRTVRCQRCGNV-----N-R----HCECG-G-FLRPSVVLFGEMLPEDAKA
WQAAQKSDLLIVLGSSLQVSPANQLPVIAKRNGAKIVIVNWEVTELD-IADIVIHNKIGDVLREIHHELKESGE-----
>tr|B7GJV3|B7GJV3_ANOFW NAD-dependent protein deacetylase, SIR2 family OS=Anoxybacillus flavithermus (strain DSM 21510 / WK1) GN=Aflv_1601 PE=4 SV=1
----------------------------------------VYSR-IYWSRKSTESGLPDFRSKSGLWRVKNPQQLASTYAMQHNRDEFIAFYQYRIRTLL
--ECEPHVGHMILADWQKQGLIH-QIVTQNVDGFHQQAGSTHVIELHGTLRTVHCSQCRQR-----E-Q----KCTCG-G-FLRPSVVLFGESLPYDAQA
WTAAERADLWIVLGSSLQVSPAKELPVIAKRSGAKLVIVNMEPTPLD-WADLLIHDKIGEVLQEIDEFL----------
>tr|M8DYE9|M8DYE9_9BACI NAD-dependent protein deacetylase OS=Anoxybacillus flavithermus AK1 GN=cobB PE=3 SV=1
----------------------------------------SYTVVFTGAGMSTESGLPDFRSKSGLWRTKNLQQLASTYALQHNREEFIAFYQYRIRALL
--ECQPHIGHTILANWQTRGLIH-QIITQNVDGFHQRAGSTNVIELHGTLRTVHCSRCKQR-----E-Q----KCTCG-G-FLRPSVVLFGEPLPHDAQA
WTAAERADLWIVLGSSLQVSPANELPVAAKRGGAKLVIVNMEPTPLD-WADLLIHDKIGEMLQEIDELL----------
>tr|A0A0D0QWT7|A0A0D0QWT7_9BACI NAD-dependent protein deacetylase OS=Anoxybacillus thermarum GN=cobB PE=3 SV=1
----------------------------------------SYTVVFTGAGMSTESGLPDFRSKSGLWRTKNPQQLASTYAMQHNRDEFIVFYQYRIRTLL
--ECKPHVGHMILADWQKRGLID-QIITQNVDGFHQQAGSTNVIELHGTLRTVHCSRCRQR-----E-Q----TCTCG-G-FLRPSVVLFGESLPYDAQA
WTAAERADLWIVLGSSLQVSPANELPVIAKRSGAKLVIVNMEPTPLD-WADLLIHGKIGEMLEEMDANYFKK-------
>tr|L0EBD7|L0EBD7_THECK NAD-dependent protein deacetylase, SIR2 family OS=Thermobacillus composti (strain DSM 18247 / JCM 13945 / KWC4) GN=Theco_0732 P
----------------------------------------RSMVLISGAGLSVDAGVKDFRS-SGWWRSIDPRTVATVEALESNYDLFHEFYAARITQLK
--TVRPHRGHGILAEWEKRGMLA-CIGTQNVDGLHQAAGSRNVHELHGTIRAFRCHACGAT---KR------KC-QCG-G-RLRPNVVLFGEMLPQEAAA
IAAIRAADAVLVIGTSLQVAPVNQLPFLTRA-GIF---INAEETGHE-QFDVFIKGRALDSLAAIQERLELL-------
>tr|F8FN62|F8FN62_PAEMK NAD-dependent protein deacetylase SIR2 family-like protein OS=Paenibacillus mucilaginosus (strain KNP414) GN=KNP414_07222 PE=4 
----------------------------------------GSLVVLTGAGCSVDAGVPDFRS-SGWWRKIDPRTVATVEALEGNYELFHEFYAARVNHLR
--SIRPHAGHEVLREWEEQGRLS-LIATQNVDRLHQAAGNREVRELHGTIREFRCHDCCRA---RE------ACGHCG-G-RLRPDVVLFGEKLPEDAVS
LAAIKAADAVLVIGTSLQVYPANQLPYMTKG-RIL---IGSERTGQE-RFHAFIQGRAAEVLPELHGRVSRRI------
>tr|U2Y4J9|U2Y4J9_GEOKU NAD-dependent protein deacetylase OS=Geobacillus kaustophilus GBlys GN=cobB PE=3 SV=1
----------------------------------------RHTVVLTGAGMSTESGLPDFRSRTGLWARFNPSELATIDALYHRRESFVEFYQYRIRTLQ
--QCQPHDGHRLLADWERRGIVQ-TIVTQNVDGFHQEAGSRRVIELHGSLRTVHCQRCGEV-----G-V----TCECG-G-VLRPSVVLFGEPLPEKAQA
WEAARQADLFVVLGSSLQVSPANQLPLVAKRSGAKLVIINWEPTELD-LADAVIHQKIGEVLNELNEQLAEVDP-----
>tr|A0A0Q0ZS31|A0A0Q0ZS31_9BACI NAD-dependent protein deacetylase 1 OS=Geobacillus sp. PA-3 GN=cobB1 PE=4 SV=1
----------------------------------------RKTVVLTGAGMSTESGLPDFRSRTGLWARFNPSELATVGALHHRHESFVEFYQYRIRTLQ
--QCQPHNGHRLLADWEQRGIVR-TIVTQNVDGFHQQAGSQCVIELHGSLRTVHCQQCGQV-----G-V----TCECG-G-VLRPSVVLFGEPLPERTQA
WEEARQADLFLVLGSSLQVSPANQLPFVAKQNGAKLVIINWEPTELD-LADAVIHQKIGEVLKEIDQQLTEGAP-----
>tr|A0A023CPB2|A0A023CPB2_GEOSE NAD-dependent protein deacetylase OS=Geobacillus stearothermophilus NUB3621 GN=cobB PE=3 SV=1
----------------------------------------RHAVVLTGAGMSTESGLPDFRSKTGLWTRFNPQQLASTYALEHHRQAFIEFYQYRIRTLQ
--ACRPHEGHMILADWQQRGLIQ-EIVTQNVDGFHQQAGSRHVIELHGSLRTVHCQQCGNV-----H-R----TCECG-G-FLRPSVVLFGEMLPEQAQA
WQAAQTADVLIILGSSLQVSPANQLPLVAKRNGAKIAIVNWEPTELD-IADVVINKKIGDVLREINDEWKAGNG-----
>tr|C5DA94|C5DA94_GEOSW NAD-dependent protein deacetylase OS=Geobacillus sp. (strain WCH70) GN=cobB PE=3 SV=1
----------------------------------------RYAVVLTGAGMSTESGLPDFRSKTGLWNRFNPQQLASTYALEHHREAFIEFYQYRIRTLR
--SCKPHEGHAILADWERNGLIK-QIITQNVDGFHQQAGSQRVIELHGSLRTVHCQRCGNV-----N-Q----ECDCG-G-FLRPSVVLFGEMLPEDAQA
WQAAQKADLLIVLGSSLQVSPANQLPLVAKRNGAKVVIVNWEPTEFD-IADIVIHEKIGNVLRDIEREWKVGND-----
>tr|K0BE08|K0BE08_9ARCH Silent information regulator protein Sir2 OS=Candidatus Nitrosopumilus sp. AR2 GN=NSED_09520 PE=3 SV=1
----------------------------------------KKIVFVTGAGISQESGIPTFRGKDGFWKNNDPMKLATIDAFYDNPKLVWEWYNERRKNIF
--QAQPNLGHKAIAELEKYV--EVVVLTQNIDGLHQKSGSTKVLELHGSIVRIKCSVCDYT-----ISGL-PFCK-CGN--ILRPDVVWFGEPLPQDVNA
IKFASQCDLMIIVGTSLVVSPANTLPIYAKQNNATLIEINTE---------IIIRKSSAEALPKLVSLFKNQL------
>tr|I3D4W0|I3D4W0_9ARCH Transcriptional regulator, Sir2 family OS=Candidatus Nitrosopumilus salaria BD31 GN=BD31_I0311 PE=3 SV=1
----------------------------------------KKIIFVTGAGISQESGIPTFRGKDGLWRNYDAMKLATIDAFYENPKLVWEWYNERRKNVF
--AAHPNQGHKAIAELEKYA--KVMVLTQNIDGLHQKAGSTEVLELHGSIIKIKCSVCDFT-----FSEI-PLCN-CGN--MLRPDVVWFGEPLPQNVKA
IVSASECDLMVIVGTSLVVSPANTLPIYAKQNNALLIEINPE---------LTIRSTSALALPKFISVLKEN-------
>tr|K0B9S9|K0B9S9_9ARCH Silent information regulator protein Sir2 OS=Candidatus Nitrosopumilus koreensis AR1 GN=NKOR_09455 PE=3 SV=1
----------------------------------------KKIVFVTGAGISQESGIPTFRGKDGLWRNYDAMKLATIDAFYENPRLVWEWYNERRKNIF
--SAHPNNGHKAIAELEKLR--DVVVLTQNIDGLHQKAGSSKVLELHGSIVKIKCTVCDFT-----FSES-PLCK-CGN--ILRPDVVWFGEALPQDVKA
IIHANQCDLMIIAGTSLAVSPANTLPMYAKQNNALLIEINPE---------LIIRNTSANILPEFISLFKEN-------
>tr|A0A0D5C0F7|A0A0D5C0F7_9ARCH NAD-dependent protein deacylase 1 OS=Candidatus Nitrosopumilus sp. NF5 GN=cobB PE=3 SV=1
----------------------------------------KKIVVVTGAGISQESGIPTFRGKDGLWRNHDAMKLATIDAFYDNPELVWTWYNERRANIF
--AAKPNPGHKAIAELEKYA--QVSVLTQNIDGLHQKAGSTEVLELHGSIIKIKCSVCDYS-----FSEI-PICK-CGN--ILRPDVVWFGESLPQDVKA
MILANQCDLMIIVGTSLVVSPANTLPIYAKQSHTTLIEINPE---------LVVRDTGANSLPELVSLFKQN-------
>tr|A0A081S791|A0A081S791_9ARCH NAD-dependent protein deacylase 1 OS=Marine Group I thaumarchaeote SCGC AAA799-E16 GN=cobB1 PE=3 SV=1
----------------------------------------QKIVFVTGAGISQESGIPTFRGKDGLWRNYDAMKLATIDAFYDNPRLVWEWYNERRSNIF
--SASPNDGHKAIAELEKFA--DVVVLTQNIDGLHQKAGSTNVLELHGSIVKIKCTVCDFT-----FSEN-PLCK-CGN--ILRPDVVWFGESLPQDVKA
IIHANQSDLMIIAGTSLVVSPANTLPIYAKQNNAMLIEVNPE---------VTIRNTSAKALPEFVSLFKTN-------
>tr|A0A0C5BT45|A0A0C5BT45_9ARCH NAD-dependent protein deacylase 1 OS=Candidatus Nitrosopumilus sp. D3C GN=cobB PE=3 SV=1
----------------------------------------KKIVFVTGAGISQESGIPTFRGKDGLWRNYDAMKLATINAFYDNPKLVWEWYNERRKNIF
--SAHPNEGHKAIADLEKYV--DVVILTQNIDGLHQKAGSTQVLELHGSIVKIKCTVCDFT-----FSDS-PLCK-CGN--ILRPDVVWFGESLPQDVEA
IIHANQCDLMVIAGTSLVVSPANTLPIYAKQNNALLIEVNPE---------LAIRNTSANTLPKLISLFREN-------
>tr|G7V9B7|G7V9B7_THELD Silent information regulator protein Sir2 OS=Thermovirga lienii (strain ATCC BAA-1197 / DSM 17291 / Cas60314) GN=Tlie_1868 PE=4
----------------------------------------KEVVVFTGAGMSTASGLPDFRG-KGLWKEKDPSLLASVGALENNYQEFCEFYRWRIKALL
--EAKPNEGHFILANWEEKGYVK-GIITQNVDGFHQEAGSKKVWELHGTLRKVRCMRCRSL-----R-T----CPNCG-G-KLRPDVVLFGESLPDLAKA
EELSLSCKCFLVLGSSLRVSPANWFPSLAKRNGAELFIINMEPTPLD-LAERVIAE-INKVLYCVSEKLQKYI------
>tr|A0A0Q3WNU5|A0A0Q3WNU5_BRECH NAD-dependent deacetylase OS=Brevibacillus choshinensis GN=AN963_03655 PE=4 SV=1
----------------------------------------STCVVFTGAGMSTESGLPDFRS-RGLWSGQDPTKLASTHSMHHNRQAFIEFYRMRIEGLL
--SCLPHAGHELLAGWETRGLIR-GIITQNVDGFHQRAGSESVAELHGTLATVRCSLCQNT-----AEG----HCQCG-G-FMRPSVVLFGESLPQTAQA
EEWTNEADLFIVFGSSLVVSPANFFPQQAKENGAKLVIVNREPTPLD-WADMVIQDLIGSLLQETDKILNL--------
>tr|A0A0H0SFH6|A0A0H0SFH6_9BACL NAD-dependent deacetylase OS=Brevibacillus formosus GN=AA984_21490 PE=4 SV=1
----------------------------------------SFTVVFTGAGMSTESGLLDFRS-SGLWRGKDPMQLASTRAMMENREAFVEFYQMRIQGLL
--SCKPHAGHECLAEWERRGLVH-GVITQNVDGFHQAAGSLAVAELHGSLAKIRCLACGTR-----DKG----ICTCG-G-FLRPGVVLFGESLPQSQQA
ISWTEQADLFIVLGSSLTVSPANWFPQHAKEKGAKLVIVNQEPTPLD-WADEVIQNRIGNVLQRVGQSLGE--------
>tr|A0A0M0KC09|A0A0M0KC09_9BACI NAD-dependent protein deacetylase OS=Bacillus okuhidensis GN=cobB PE=3 SV=1
----------------------------------------KKIVIFTGAGMSTESGVPDFRS-RGLWQGKKPEALASVDAMDHNREAFIDFYRMRIEGLQ
--GVRPHKGYDVLAAWEKELPIT-SIITQNTDGLHEQAGSEVVLPLHGSIQRSYCVACGQR-----N-E----YCSCG-G-FIRPAVVLFGEMLNTDTLA
ERHTKEADLFLVLGSSLVVSPANLFPKIAKECGAKLVIVNHDETPLD-LADLVIQDSIGTFLEETNRALQA--------
>sp|Q5WKC8|NPD_BACSK NAD-dependent protein deacetylase OS=Bacillus clausii (strain KSM-K16) GN=cobB PE=3 SV=1
----------------------------------------QRIVVFTGAGMSTESGVPDFRS-RGLCKGNNPEALASLQAMNDNREAFVDFYRRRMEQLQ
--HVQPHKGYDVLATWEQQLSVT-AIITQNTDGLHERAGNQRVLPLHGSIQKLYCIQCGQR-----N-Q----SCSCG-G-FIRPSVVLFGEPLDSNILA
EQHSIEADVFIVLGSSLVVSPANLFPRIAKEHGAKLIIVNHDSTPLD-IADYVVNDPIGSFLVETNRALQK--------
>tr|V6MLT9|V6MLT9_9BACL NAD-dependent protein deacetylase OS=Brevibacillus panacihumi W25 GN=cobB PE=3 SV=1
----------------------------------------KSAVVFTGAGMSTESGLPDFRS-SGLWQGKDPMQLASTQAMRNHREAFIDFYRKRIEGLL
--ACEPHAGHECLAALEQAGKVK-GIITQNVDGFHHRAGSKKVAQLHGTLETVHCTRCEQR-----QDG----ICSCT-G-FLRPSVVLFGEALPAMAQA
QEWSDQADLFVVLGSSLTVSPANWFPQRAKEGGARLVIVNQEPTPLD-WADLVISDRIGAVLTEVCQQI----------
>tr|J2HZQ3|J2HZQ3_9BACL NAD-dependent protein deacetylase OS=Brevibacillus sp. CF112 GN=cobB PE=3 SV=1
----------------------------------------PGAVVFTGAGMSTESGLPDFRS-TGLWRGNDPQKLASTQAMRSNRESFVEFYRMRIEGLC
--SCKPHAGHEILAKWEQRGLLA-GIITQNVDGFHQRAGSRAVAQLHGTLTTVSCIRCRKR-----EEG----QCECG-G-FVRPDVVLFGESLPQSQLA
VEWTERAPLLIVLGSSLTVSPANWFPQRAKENGARLVIVNQEPTPLD-WADLVVHDKIGELLSRTEQWLHR--------
>tr|M8DBM9|M8DBM9_9BACL NAD-dependent protein deacetylase OS=Brevibacillus borstelensis AK1 GN=cobB PE=3 SV=1
----------------------------------------RHAIVFTGAGMSTESGLPDFRSRTGWWQGKDPARLASTDALRNNREEFVSFYRMRVEGLL
--SCKPHQGHVILAEWERRGQIK-GIITQNVDGFHQRAGSRRVAELHGTLATLTCMRCTNR-----QGG----ACECG-G-FLRPSVVLFGESLPEAAQA
VEWTERADLFLVLGSSLAVSPANWFPEQAKARGAKLVIINRDATHLD-IADLLIQDPIGDVLRKAEIEWKH--------
>tr|A0A0J5W2I0|A0A0J5W2I0_BACFI NAD-dependent protein deacetylase OS=Bacillus firmus GN=cobB PE=3 SV=1
----------------------------------------NYTVILTGAGMSTESGLPDFRSNNGLWNGKDPGKIASTDALNENVNEFIEFYRHRVIGLK
--ECTPHQGHYILADWEKRDIIK-SIITQNVDGFHGLAGSKKISELHGNLQTLHCQKCKKE-----GQF----CN-CG-G-VLRPSVVLFGEMLPEEAFA
ADETEKAELFIVLGSSLTVTPANQFPLIAKQNGAKLVIINMEPTDFD-YADEVIHEKIGEVLEELDRALMQWEN-----
>tr|A0A024Q6C2|A0A024Q6C2_9BACI NAD-dependent protein deacetylase OS=Virgibacillus sp. Vm-5 GN=cobB PE=3 SV=1
----------------------------------------SYVVVFTGAGMSTESGLPDFRSNQGLWNNQDPSQIASTEALNNNVEAFTQFYRERVIGVK
--TYQPHKGHYILADWEKQGIVQ-SVITQNVDGFHQQAGSKRVAELHGTLQKLHCQSCQRE-----RGY----C-ECG-G-ILRPSIVLFGETLPVDAMA
LLESEKADLFIVLGSSLSVTPANQFPLIAKERGARLVIVNREPTAFD-YADQLIQNQLGDVLAEIE-------------
>tr|W9AP37|W9AP37_9BACI NAD-dependent protein deacetylase OS=Oceanobacillus picturae GN=cobB PE=3 SV=1
----------------------------------------TYTVVFTGAGMSTESGLPDFRSKQGLWNNLDPSEIASTDALNKNVHAFTEFYRQRVLGVK
--TYEPHKGHYILADWEKQGKLK-SIITQNVDGFHQKAGSQKVAELHGTLQTLHCQSCNKA-----KEY----C-DCG-G-ILRPSIVLFGEALPQSAQA
FTEAQACDLFVVLGSSLSVTPANQFPLIAKDSGAKLVIINREETDLD-YADLVIHNNIGDILKELDV------------
>tr|A0A0J1IID9|A0A0J1IID9_BACCI NAD-dependent deacetylase OS=Bacillus circulans GN=ABW02_14305 PE=4 SV=1
----------------------------------------NYFVIFTGAGMSTESGLPDFRSNKGLWTAEKKQYLSSTSALNNHVQEFIEFYRNRVQGIH
--EFKPHHGYYILSDWERKGYVK-QIITQNVDGFHEEAGNQKVAELHGTLKKIHCEICGKE-----DNY----C-SCG-G-ILRPSIVLFGEMLPEQPRA
EEAAIKSDVFLVLGSSLSVSPANQFPLLAKQTGAKLIIINKEQTQMD-IADIVIHESIGKVLEEINLKL----------
>tr|A0A0M0GHF3|A0A0M0GHF3_SPOGL NAD-dependent protein deacetylase OS=Sporosarcina globispora GN=cobB PE=3 SV=1
----------------------------------------KYTVILTGAGMSTESGLPDFRSNNGLWNGKDPGKIASTDALNQNVKEFIEFYRHRVIGLK
--ECKPHKGHYILADWEKRDIIK-SIITQNVDGFHKLAGSKNISELHGDLQTLHCQKCKKE-----GHF----CS-CA-G-VLRPSVVLFGEMLPEHAFA
ADESERAELFIVLGSSLSVTPANQFPLIAKQNGAKLVIINIEPTDFD-HADEVIHNKIGEVLEDLDRAFKLY-------
>tr|U5L815|U5L815_9BACI NAD-dependent protein deacetylase OS=Bacillus infantis NRRL B-14911 GN=cobB PE=3 SV=1
----------------------------------------SYTVILTGAGMSTESGLPDFRSGSGLTNTVDYGKIASTEALNHHVSEFIEFYRRRVMGLK
--ECSPHAGHYILADWERRGIVQ-SIITQNVDGFHQAAGSRNVAELHGTLQQVHCQTCGKE-----EHF----CSDCG-G-ILRPSIVLFGEMLPEEAFA
AAESEKADLFIVLGSSLSVTPANQFPLIAKQCGAKLVIINMDPTDLD-YADKVINGKAGELLKELDAEIGKM-------
>tr|F7Z1I5|F7Z1I5_BACC6 NAD-dependent protein deacetylase OS=Bacillus coagulans (strain 2-6) GN=cobB PE=3 SV=1
----------------------------------------RHTVVFTGAGMSTESGLPDFRSHNGLWKKKDPSQIATTKALNENVEAFVEFYRERVLGVK
--EFGPHQGHYILAKWEQQGFIR-SIITQNVDGFHQEAGSKRVAELHGTLQKVHCQTCGRN-----NDF----C-ECG-G-VLRPNIVLFGEALPQEAFA
LEEAEKADLFIVLGSSLSVTPANQFPLIAKENGAKLVIVNMEPTQFD-YADQVIHDKIGQLLIELDKKISSPIK-----
>tr|W7KZD3|W7KZD3_BACFI NAD-dependent protein deacetylase OS=Bacillus firmus DS1 GN=cobB PE=3 SV=1
----------------------------------------NYTVILSGAGMSTESGLPDFRSNNGLWNAKDPGRIASTDALNDNVKEFIDFYRHRVIGLK
--ECSPHKGYYILADWEKRGILK-SIITQNVDGFHRLAGSENLSELHGNLQTLHCQECKEG-----GHI----CY-CG-G-MLRPSVVLFGEMLPEQPFA
AEESEKAELFIVLGSSLTVTPANQFPLIAKQNGAKLVIINMEPTEFD-YADEVIHDKIGEVLEELDHAFQQREN-----
>tr|A0A0N0YFT3|A0A0N0YFT3_THEVU NAD-dependent deacetylase OS=Thermoactinomyces vulgaris GN=ADL26_00345 PE=4 SV=1
----------------------------------------NKTVIFTGAGMSTESGLPDFRSKQGMWRDKDPTYYASTYALTHHRDPFIQFYRQRIKGLL
--KVKPHEGHTVLAEWEKKGWID-GIVTQNVDGLHQAAGSKRVAALHGSLRELVCMECQKK-----DAG----MCVCG-G-FIRPKVVLFGENLPEQERA
EALIDGVELLIVLGSSLQVSPANFFPVRAKEQGAKLVIINWEPTDFD-EADLVVNGKIGAWLQQVHAELLIKNK-----
>tr|A0A0K1X907|A0A0K1X907_9GAMM NAD-dependent deacetylase OS=Pseudomonadaceae bacterium E1148 GN=AKN89_08680 PE=4 SV=1
----------------------------------------KHTLVFSGAGMSTESGLPDFRSERGLWKKFNPSELAHVRALEHNRDEFTAFYQARLADIN
--QYQPHSGHYILARWEQHGLLQ-GIITQNVDGFHGDAGSQQVLELHGSFRDLHCHSCGAT-----GSA----C-PCG-G-TVRPGIVLFGEMLPQDTRA
EQLTRACDLFIVLGSSLSVSPANGFPHLAKQMGAKLVIINYEPTDMD-LADLVINQSIKGLLEALNQQLTAA-------
>tr|D5EFR9|D5EFR9_AMICL Silent information regulator protein Sir2 OS=Aminobacterium colombiense (strain DSM 12261 / ALA-1) GN=Amico_1280 PE=4 SV=1
----------------------------------------HHLVIFSGAGMSTSSGLPDFRS-QGLWSRYNPMALASIDAMENNREAFLDFYRYRINALK
--NASPNLGHCILSKWEEENLLQ-GIITQNVDGFHQEAGCRNVVELHGTLRKARCSRCKNL-----E-E----CPDCK-G-ILRPGVVLFGEMLPDTPRA
HELSLKSDVFMVLGSSLNVSPANFFPLEAHEAGAKLIILNREPTQYD-MASFVVRELVDA-LERIQQIMHREGG-----
>tr|H3SFZ3|H3SFZ3_9BACL NAD-dependent deacetylase OS=Paenibacillus dendritiformis C454 GN=PDENDC454_12240 PE=4 SV=1
----------------------------------------ASTVVFSGAGMSTESGLQDFRSDRGMWNDRDPAALASLDAMEEHHDEFARFYRWRIGEML
--KHGPNPGHRILADWERRGVIH-GVITQNVENYHEQAGTSAIAKLHGDLGTLRCMTCHAD-----PKRL---RCVCG-G-RVRPNIVLFGEWLPEREQA
DAMLDGVELLLVLGSSLQVSPANQFPRLAKERGARLVIVNREPTPAD-IADLIIRHSIGEVLRWTDAQLARLPH-----
>tr|C6CZ67|C6CZ67_PAESJ Silent information regulator protein Sir2 OS=Paenibacillus sp. (strain JDR-2) GN=Pjdr2_4746 PE=4 SV=1
----------------------------------------SSTIIFSGAGMSTESGLQDFRSDRGMWNNRNPIELADIEAIDSNREEFIRFYQWRIHEMN
--SHQPNDGHRILADWENRGLIK-GIITQNVENYHEQAGTRQIAKLHGDLGTLHCMKCNKM-----PEKM---VCSCG-G-FIRPNVVLFGEMLRQSALA
NKLMKDVELFIVLGSSLQVSPANQYPKRAKENGANLVIINNDPTPAD-YADIVINNSIGSSLRMIDDLLKI--------
>tr|A0A0Q9LKV6|A0A0Q9LKV6_9BACL NAD-dependent deacetylase OS=Paenibacillus sp. Soil724D2 GN=ASG85_20430 PE=4 SV=1
----------------------------------------SSTVIFSGAGMSTESGLQDFRSDRGMWNNRNPIELADIEAINSNRSEFIRFYQWRIQEMM
--NHQPNEGHHILSKWESKGLIK-GIITQNVENYHEQAGNKRIAKLHGDLGTLRCMSCDKI-----PVER---SCNCG-G-FIRPNVVLFGEMLPQASFA
ENLLLSTDLFIVLGSSLQVSPANQLPKRAKQCGTRLVIVNHDPTPLD-YADLVINLSIGEVLSKADQKLEKS-------
>tr|G9PW87|G9PW87_9BACT Uncharacterized protein OS=Synergistes sp. 3_1_syn1 GN=HMPREF1006_01657 PE=4 SV=1
----------------------------------------GGVTIFSGAGLSTESGLQDFRS-DGIWAHADPTRLASVGALEDNYEEFLEFYKARLYVPE
--EIQPNIGHKIIAKWEKEGYVD-GVITQNVDRLHQKAGSVNVWELHGSLEPVRCHSCGGD---GK------PCARCG-G-RLRPSVVLFGEMLPQRPAA
DELSDGCRTFIVLGSSLVVSPANYFPRQAKS-RARLAIVNRDPTPLD-IADIVVHEGIGAFLTEVEKDMQGR-------
>tr|A0A095XPM2|A0A095XPM2_9FIRM NAD-dependent deacetylase OS=Tissierellia bacterium S5-A11 GN=HMPREF1633_05240 PE=4 SV=1
----------------------------------------KNMYALTGAGISTESGIPDFRS-TGYYKEFDGATALSRDVLLGDPDRFYHEGFVMLKDLF
--AKKPNAGHKALKKLEDLGYLK-GVITQNIDNLHTLAGSKKVFEVHGHTRTVHCMSCHKD---LVEEEI-PRCPACQ-G-VLRPDVVMFGDMMPQDFAY
EAM-ETCDLLLVAGSSLVVAPVSYLPGMAKK----LIIINKEVTPYD-KADVVIHEGIGQALTKILSLVEEGAS-----
>tr|U7UHZ9|U7UHZ9_9FIRM Transcriptional regulator, Sir2 family OS=Peptoniphilus sp. BV3C26 GN=HMPREF1253_1851 PE=4 SV=1
----------------------------------------KKIFALTGAGISTESGIPDFRS-TGYYSKMDPMAALSKDVLLKNPKRFYSEGYVILSDLN
--DKSPNQGHIALKELEDLGYLQ-GIITQNIDNLHTKAGSSNIYEVHGETRDVRCMSCGKY---QVKNII-PKCN-CG-G-VIRPNVVMFGDMMPDDFAA
QDL-EDADLLIVIGSSLQVSPVNYLPRYVKN----LIIINNDPTPFD-YAQVVIHEPAGKTLKKIIEALK---------
>tr|E0NP08|E0NP08_9FIRM Transcriptional regulator, Sir2 family OS=Peptoniphilus duerdenii ATCC BAA-1640 GN=HMPREF9225_1897 PE=4 SV=1
----------------------------------------NGVFALTGAGISTDSGIPDFRS-TGYYQKFDPVTALSREVLMYEPERFYSEGYVILKDLF
--DRKPNKGHLALAKMEELGYLD-GIITQNIDNLHFKAGSKNIFEVHGETRDVHCIKCGAY---KVEKEI-PKCEKCG-G-TVRPNVVMFGDSMPLDFAY
TAA-SGKDTLIVVGSSLTVSPVNFFPEMFPH----LIIINNDRTPFD-RADFVFHENSSKVLSEIVEELKIV-------
>tr|G4D435|G4D435_9FIRM NAD-dependent deacetylase 2 OS=Peptoniphilus indolicus ATCC 29427 GN=HMPREF9129_1165 PE=4 SV=1
----------------------------------------KKVFALTGAGISTESGIPDFRS-SGYYKKFDPIRALSVDTMLGDPERFYSEGYLILKDLN
--DRKPNNGHIALAKLEEAGYLS-GIITQNIDNLHFEAGSKNVYEVHGETRGVHCMKCGTY---KVDGEI-PKCEKCG-G-VVRSNVVMFGDMMPDDYGT
YEL-QDTDLLIVIGSSLTVSPVNFLPRYVEN----LIIINNTPTPED-RAKFVFRENSGEVLMNIYNEVMNG-------
>tr|D7N8V8|D7N8V8_9FIRM NAD-dependent deacetylase OS=Peptoniphilus sp. oral taxon 386 str. F0131 GN=npdA PE=4 SV=1
----------------------------------------KKTFALTGAGISTESGIPDFRS-TGYYSKLDPMLALSRDILINNPKRFYKEGYVILEDLS
--EKKPNRGHIVLAELENMGLLN-GVITQNIDNLHRKAGSKNIYEVHGETGRVHCISCNEV---KVSGEI-PHCDKCG-G-VIRPNVVMFGDMMPGDFAV
EEL-MDTELLIVIGSSLTVSPVNYLPRYVKK----LVIINDTPTLQD-MAEVVVRGKSGEILSQILDEVKKLR------
>tr|E4L0I8|E4L0I8_9FIRM Putative NAD-dependent deacetylase OS=Peptoniphilus harei ACS-146-V-Sch2b GN=HMPREF9286_0831 PE=4 SV=1
----------------------------------------KKVFALTGAGISTDSGIPDFRS-SGYYSKMDPALALSKDRLLNHPEIFYKEGYKILEDLN
--DQEPNGGHKALAKMEEEGFLA-GIITQNIDNLHAKAGSKNIYEVHGETRGTHCMKCGKL---KVAGEI-PKCDACG-G-VIRPNVVMFGDMMPDDFGA
REL-DSTDTLIVVGSSLTVSPVNFLPNYVDH----LIIINNDPTPMD-RADVVIHENSTRVLEEILKELEARS------
>tr|D1VVW6|D1VVW6_9FIRM Transcriptional regulator, Sir2 family OS=Peptoniphilus lacrimalis 315-B GN=HMPREF0628_0901 PE=4 SV=1
----------------------------------------SKVMALTGAGISTDSGIPDFRG-NGYYKDMDPVRSLSKDRLLNEPEKFYKEGYKILLDLN
--SKKPNKGHLALAKMEKMGLIK-GIITQNIDNLHYKAQSSNIYEVHGETRGIHCMDCGKL---KVQGQI-PKCT-CG-G-TLRPNVVMFGDMMPKDFAI
DEM-EDTDTLIVVGTSLTVSPVNMLPRYADN----LIIINQSPTPYD-HADIVFHENSSEVLSQILEELEKNDL-----
>tr|A0A090I073|A0A090I073_9FIRM NAD-dependent protein deacetylase 2 OS=Peptoniphilus sp. 1-1 GN=cobB2 PE=4 SV=1
----------------------------------------SKTFALTGAGISTESGIPDFRS-TGYYTKMDPMKALSRDVLLNDPKRFYSEGFIILKDLY
--DKKPNKGHLALAKLEEMNLLN-GIITQNIDNLHVKAGNKNVYEVHGESRNVHCVNCGMV---KVKGEI-PKCDKCG-G-TLRPNVVMFGDMMPDDFAQ
DEL-IDTDLMIIVGSSLTVSPVNFLPNMVDK----LIIINQSPTPFD-KADVVFHEGAGEVLEKILDEINKLI------
>tr|A6TNA0|A6TNA0_ALKMQ Silent information regulator protein Sir2 OS=Alkaliphilus metalliredigens (strain QYMF) GN=Amet_1469 PE=4 SV=1
----------------------------------------KDTVILTGAGMDTESNIPDFRS-KGWWRSIDPRTVANIDTFYENYSLFHEFYDMRLRLLV
--GIQPHKGHYILSDLEKKGMIR-SIATQNVAGLHVMAGSQNVYELHGNIRKIRCNNCNHR---VE------TCGSCGDK-GLRPSVILFGETLPPKASA
LRDIQKCDLLIVIGTSLEVYPVNHLPMLTKG-KVF---INNEERSTD-AFDLTIIGKAKEVLEALNHYLLL--------
>tr|M1Z415|M1Z415_9FIRM NAD-dependent protein deacylase 2 OS=[Clostridium] ultunense Esp GN=cobB PE=4 SV=1
----------------------------------------NNMVVMTGAGMDTESNIPDFRS-DGLWYKMDPAKVATVEALHQNYPLFHEFYSARIKNMD
--NITPHEGHYVLAELEEKGYIK-SLATQNISGLHAMAGSRNIYELHGNIREIRCNECHTE---KK------NCNNCGKN-ALRPGIVLFGEMLPTNTRA
MRDVENSEILMVIGTSLQVYPVNQMPYMTRG-KVY---INMEQ-ARG-DFDIEIIGRAGEVLTEIKEMLL---------
>tr|C0GDD5|C0GDD5_9FIRM Silent information regulator protein Sir2 OS=Dethiobacter alkaliphilus AHT 1 GN=DealDRAFT_0586 PE=4 SV=1
----------------------------------------DNTVVLTGAGMDTDSNIPDFRG-GGWWKNIDPRTVANIDTFAQNYSLFQEFYSMRIKLLQ
--NVKPHPGHYILADLEKRGIIK-SIATQNISGLHRLAGSEKVYELHGNIATVRCNSCGRD---GE------NCTGCNTG-ALRPNVVLFGEALPQDVQA
LSHIQRADLLLVIGTSLEVSPVNQLPFQAKG-RVF---INKEDCSQH-SFDLTLLGNAKEVLKKLSDRLT---------
>tr|A0A0K1IVB5|A0A0K1IVB5_9EURY NAD-dependent protein deacetylase OS=Haloferax gibbonsii GN=ABY42_10985 PE=4 SV=1
----------------------------------------DTAVAFTGAGMSTASGIPDFRG-DGIWETEFDPASFHRDRFVNDPAGFWRDRVRLQERPD
--GVEPNPGHDALSALESRGVLD-AVVTQNTDGLHRDAGSDRVVELHGNAAEVVCEDCGAP---AVAGDA-PTCDDCG-G-LLKPGVVLFGERLPRVAEA
NRLAGDADVFLSLGSSLTVHPAAGLAGRAAE-GS-LVVVNFDATQYD-RADRVVRGDLAAFLPEVEKRVERV-------
>tr|I3R6T0|I3R6T0_HALMT NAD-dependent protein deacetylase OS=Haloferax mediterranei (strain ATCC 33500 / DSM 1411 / JCM 8866 / NBRC 14739 / NCIMB 2177 
----------------------------------------EFVVAFTGAGMSTASGIPDFRG-DGIWNTEFDPASFHRDRFVNDPAGFWRERVRLHERPD
--GVAPNAGHDVLAELESRGILD-RVITQNTDGLHRESGSNRVVELHGNASQVVCEDCEST---QVAGDA-ATCGECG-G-IVKPDVVLFGERLPRVAKA
NRLADKADVFLALGSSLTVHPAAGLAGRAAE-DS-LVVVNFDETQYD-SADRVVRDDLTEFLPAVEELV----------
>tr|M0IJM5|M0IJM5_9EURY Sir2 family transcriptional regulator / NAD-dependent deacetylase OS=Haloferax mucosum ATCC BAA-1512 GN=C440_04238 PE=4 SV=1
----------------------------------------DVAVALTGAGMSTASGVPDFRG-DGIWNSEFDPASFHRDRFVNDPAGFWQERVRLHERPD
--DVAPNTGHDALAKLESRGILH-TVITQNTDGLHREAGSYEVVELHGNASQVVCEDCESA---QAAGDV-ATCDKCG-G-VVKPDVVLFGEQLPQVAKA
NRLADKADVFLALGSSLTVHPAAGLAGRAAE-DS-LVVVNFDETQYD-EADRVIRDDLTEFLPAVEALV----------
>tr|M0HG21|M0HG21_9EURY Sir2 family transcriptional regulator / NAD-dependent deacetylase OS=Haloferax elongans ATCC BAA-1513 GN=C453_16723 PE=4 SV=1
----------------------------------------DVAVALTGAGMSTASGIPDFRG-DGIWNTEFDPASFHRDRFVNDPAGFWRDRLRLHERPD
--EVGPNAGHDALATLESRNVLD-AVITQNTDGLHRAAGSERVVELHGNAADVVCESCGSM---QVDDAV-ATCRTCD-G-VLKPDVVLFGEQLPRAAEA
TTLADDADIMLALGSSLTVHPAAGLAGRAAE-GS-LVVVNFDETEYD-RADVVVRADLTEFLPAVETRL----------
>tr|A4J646|A4J646_DESRM Silent information regulator protein Sir2 OS=Desulfotomaculum reducens (strain MI-1) GN=Dred_2032 PE=4 SV=1
----------------------------------------GKTIALTGAGISTESGIPDFRSNTGLWNQYDPQEVASIQALKKNPESFYALNFQWWDVCL
--KAKPNNAHFALARLEKMGWLL-GVITQNIDGLHQHAGSKRVWEVHGNLKGCSCLSCKKQ---QL------RCPFCG-G-LLRPDVVLFGDAMPEDFAE
KVM-SGCQLLLVIGSSLQVYPVASLPQLSSK----TVIINKEPTTWD-HSDVVFHEPASQVLCDLVDSLNNLQG-----
>tr|F6DPU5|F6DPU5_DESRL Silent information regulator protein Sir2 OS=Desulfotomaculum ruminis (strain ATCC 23193 / DSM 2154 / NCIB 8452 / DL) GN=Desru_
----------------------------------------GQVLALTGAGASTESGIPDFRSESGLWNGMPVEELASIRALRKDPQKFYDFHLRWWEVCL
--GAKPNDTHYALAKLEQTGWLL-GIITQNIDGLHQKAGSRHLWEVHGHLRTCYCPQCGQR---DY------LCPDCG-W-ILRPRVVLFGDPMPKDYAE
KVL-SGCQLLLVVGTSLQVHPVNTLPQRARR----MVIINHEPTPWD-SAELVFRESSGKVLTDITKHLAHIPG-----
>tr|K8DZM2|K8DZM2_9FIRM NAD-dependent deacetylase 2 OS=Desulfotomaculum hydrothermale Lam5 = DSM 18033 GN=cobB PE=4 SV=1
----------------------------------------GKVLALTGAGISTESGIPDFRSNGGLWVRFDPAEIASVQALKRDPATFYRFHLPWWQTCL
--KAAPNVGHKALAQLEKAGWLL-GVITQNIDGLHQAAGSQRVWEVHGHLRNCHCLGCGQQ---SF------FCTQCG-N-LLRPQVVLFGDPMPPDYAE
KVL-SGCQLLLIIGSSMQVQPVANLPALARQ----VVIVNREATPWD-YAELVFHESAGQVLKDLVAGLQGKTG-----
>tr|B2A496|B2A496_NATTJ Silent information regulator protein Sir2 OS=Natranaerobius thermophilus (strain ATCC BAA-1301 / DSM 18059 / JW/NM-WN-LF) GN=Nt
----------------------------------------EEPYVLTGAGISTESGIPDFRG-DGLWTKIDPMQYSTREVLMSVPEKFYEYGFERFKQLA
--NKEPNQGHKILADLEKHGVIS-GIVTQNIDGLHQKAGSKQVFEVHGNTRKCYCLGCNQE---QLEQKD-PKCKECG-G-MLRPDIILFGDQMPDLFVT
TVLKQRCDFLLVIGTSLQVYPVAALAELGIP----MGIINLEETPFD-QAEVVIQGKCGETLSQLWDHMKDELS-----
>tr|F6B2N0|F6B2N0_DESCC NAD-dependent deacetylase OS=Desulfotomaculum carboxydivorans (strain DSM 14880 / VKM B-2319 / CO-1-SRB) GN=Desca_0985 PE=4 SV=
----------------------------------------GKTVALTGAGASTESGIPDFRSDSGLWNQVDPQKSVSIRALKKDPQSFYRFNFQWWDVCL
--QAKPNACHHSLARLEEQGWLL-GVITQNIDGLHQRAGSQRVWEVHGHLRSCHCLHCGRR---EY------HC-TCG-G-LLRPDVVLFGDAMPEDYAE
QVL-SGCQLLLVIGSSLQVQPVAGLPRLARR----VVIINHDPTPWD-SAELVFRESAGQVLADVVKQLGNNTG-----
>tr|S4D6D9|S4D6D9_ENTFL Transcriptional regulator, Sir2 family OS=Enterococcus faecalis 13-SD-W-01 GN=D920_00957 PE=4 SV=1
----------------------------------------DRITFLTGAGVSTPSGIPDYRSLDGVYR-ERPEYLLSRQALLEEPQKFYTFIK----HHP
--DAEPNLIHQTIAQLEKEK--IVWTISQNIDGLHRAAGTSQLIEFHGNLYNCTCMNCGKE-------D---RHNSCG-G-QIRPMIVLYGEGFQPKVQA
VEAVSQAELIVIIGTSFQVYPFRSLIEYKQKE-AEILVINQTEIDLD-EYF-FAQYDGIEVFEQLNKGAENDKN-----
>tr|A7I3A1|A7I3A1_CAMHC NAD-dependent deacetylase (Regulatory protein SIR2-like protein) OS=Campylobacter hominis (strain ATCC BAA-381 / LMG 19568 / NC
----------------------------------------NEILILSGAGLSADSGLSTFRGNGGLWENYNVMEICSVEGFAKDRQKVLNFYDNRRIELK
--NVAPNSAHKMIAEIKAKYPDKIAILTQNIDDLLERAGCHDVVHLHGELTKLRCESCEHY-----DK----KCPKCGSS-RVRHNVVMFGEMAPFYAAR
LR---DMKLFICIGSSGEVLDVANYAYMAEF--SILNNLEK-SF-VD-NFTKVYNETAVNAALKIKLDIENFIK-----
>tr|Q4HTH2|Q4HTH2_CAMUP Transcription regulator, Sir2 family OS=Campylobacter upsaliensis RM3195 GN=CUP0709 PE=4 SV=1
----------------------------------------KKVMILSGAGLSAPSGLKTFRDNGGLWEEYDVMEVCSASGFRRNPQKVLDFYDLRRASLA
--RVKPNYAHFALAKLKAKFPHNIFMLTQNVDDLLERAKCEGVIHLHGFLSELRCLQCEMY-----NK----LCPSCQSA-NLRHNIVMFEEQAPEYQEL
LK---QTHLFIAIGTSGAVLPVGHYAKMCEK--SILNLLESDEG-LE-CFTKVYKEDILSAVDKIILDVEEFLS-----
>tr|A0A0B0Q5R6|A0A0B0Q5R6_9PROT NAD-dependent deacetylase OS=Sulfurospirillum sp. MES GN=OA34_04695 PE=4 SV=1
----------------------------------------AKVVIFSGAGISAESGLSTFRDADGLWEKYRIEEICQAGCLSWNRENTLAFYDARREQLS
--AVEPNTAHHSIAKLQAKFPNDIAIITQNVDDLFERAGCKDVLHLHGFLPRLRCEECGVY-----RTF---TCKNCGG--SFRPDIVFFGEAAPMYEDA
ME---DCQFLAIIGSSGNVVAMDHFALHVKH--SILNNLEKSDAINE-VYTKVLHQKATEAVDEIVEDVERFLR-----
>tr|W6EFC5|W6EFC5_SULMU NAD-dependent protein deacetylase of SIR2 family OS=Sulfurospirillum multivorans DSM 12446 GN=SMUL_2127 PE=4 SV=1
----------------------------------------ARVVIFSGAGISAESGLSTFRDTDGLWEKYRIEEICQAGCLSWNRENTLTFYDARREQLS
--SVTPNAAHYALSQLQEKYPNNIAIITQNVDDLFERAGCKDVLHLHGFLPRLRCEQCGAY-----RTF---TCKECGG--SFRPDIVFFGEPAPMYEEA
ME---ECQFLVIIGSSGNVVAMDHFALHVKV--SILNNLEPSDAINE-VYTKVLHQKATEAVDEIVEDIERFMQ-----
>tr|I3XY01|I3XY01_SULBS NAD-dependent protein deacetylase, SIR2 family OS=Sulfurospirillum barnesii (strain ATCC 700032 / DSM 10660 / SES-3) GN=Sulba_1
----------------------------------------AKVVIFSGAGISAESGLSTFRDAGGLWEKYRIEEICQAGCLSWNRENTLTFYDARREQLA
--SVKPNAAHYALSKLHEKYPNDIAIITQNVDDLFERAGCKDVLHLHGFLPRLRCEQCGAY-----RTF---TCKSCNG--SLRPDIVFFGESAPMYEEA
IQ---GCEFLVIIGSSGNVIAMDHFALHVKI--SILNNLERSDAINE-VYTKVLHKKATEAMDEIVGDVERFLE-----
>tr|J0L3D6|J0L3D6_9HELI NAD-dependent protein deacetylase, SIR2 family OS=Thiovulum sp. ES GN=ThvES_00017210 PE=4 SV=1
----------------------------------------YKILILSGAGLSAESGLKTFRDHNGMWENYDVMEVCSVEGFRKDRNLVNEFYDKRREDLK
--RAEPNFAHKKIAELKKKYPNEIAIVTQNVDDLIERSGCSDVLHLHGTLSDLRCEICGKY-----GE----KCPNCDEVHEIRHNVVMFGEPAPNYNKI
ID---QIEMFVVIGSSGEVLPLGAIARNFHN--SILNNLYPDET-LD-NFKRVIHKPATEGILEIEKIVEDFLK-----
>tr|A0A0A8I9W3|A0A0A8I9W3_CAMLA NAD-dependent deacetylase, Sir2 family OS=Campylobacter lari RM16712 GN=npdA PE=4 SV=1
----------------------------------------KQVMILSGAGLSVPSGIKTFRASGGLWEEHDVMEVCSATGFRKNPKKVLEFYNKRRKELA
--SVKPNHAHEIIALLKQKFPKQISILTQNVDDLLERASCEEVVHLHGFLPELRCLECENY-----DK----ICPKCQSK-SVRHNIVMFEEMAPNYKDK
LQ---NCDLFVCIGTSGQVLPVGEYARVCKQ--SILNNLDEDKY-LE-NFTKVYIEDVCTAIDKIKIDIENFLE-----
>tr|E4U1W1|E4U1W1_SULKY Silent information regulator protein Sir2 OS=Sulfuricurvum kujiense (strain ATCC BAA-921 / DSM 16994 / JCM 11577 / YK-1) GN=Sul
----------------------------------------KKVLILSGAGISAESGIRTFRDTNGLWEEYDVMEVCSLTGFERNPKLVADFYDARRRDLH
--DKLPNAAHEMIARLKQHYPDQIEVLTQNVDDLFERAGCPDVIHLHGTLTDLRCEECGWY-----GS----TCPSCESD-NIRHNVVMFGEEAPMYARA
IE---ECDLFVVIGSSGQVINTAWIAQWFEH--SILNNLESDDM-LD-FFKTLYIEKATTAAPKIEAEIEYFLA-----
>tr|A0A0Q2TGC6|A0A0Q2TGC6_CAMCO NAD-dependent deacetylase OS=Campylobacter coli CVM 41932 GN=Y855_00975 PE=4 SV=1
----------------------------------------KNIMILSGAGLSAPSGLKTFRDNDGLWEEYDVMEVCSATGFRKNPKKVLDFYDARRVQLQ
--SVKPNYAHEKIVQLKEKWGKNLFILTQNVDDLLERAGCREVVHLHGFLPELRCLSCDEY-----DK----QCPKCKSK-DLRHNIVMFEEQAPAYASL
LN---QTSLFISVGTSGAVLPVERYASMCEK--SILNIYEKDAN-LE-YFDKIYIEDIISAIDKIALDIENFMK-----
>tr|D2MYH0|D2MYH0_CAMJU NAD-dependent deacetylase OS=Campylobacter jejuni subsp. jejuni 414 GN=C414_000240017 PE=3 SV=1
----------------------------------------KNIMILSGAGLSAPSGLKTFRDNGGLWQDYDVMEVCSATGFRKNPKKVLDFYDARRLELA
--NVKPNHAHKQIAKLKEKWGKNLFVLTQNVDDLLERAGCKDVVHLHGFLPELRCLKCEEY-----NK----ICPKCKSQ-NLRHNIVMFEEQAPAYTSL
LG---QTSLFISIGTSGAVLPVEHYASMCEK--SILNIYEKDAK-LE-YFDKIYIEDILSSIDKIALDIENFMK-----
>tr|G2HWV6|G2HWV6_9PROT NAD-dependent deacetylase OS=Arcobacter sp. L GN=ABLL_1734 PE=4 SV=1
----------------------------------------AKVIILSGAGISAESGISTFRDSGGLWENHKIEDVCMLGCLEKNRVETLNFYDLRRVELK
--DKEPNHAHKVIANLKEKYKDKIAVITQNVDDMFEKAGCVDVLHLHGFLKEVKCESCENY-----GSF--EVCPKCDN--FLRPNIVFFGEMAPKYQME
FN---DCEVLVIIGTSGAVINTDMFLPDIKL--SILNNIEPSDYLME-LYTKVLHKEATKAIDEIAFDIEEFLI-----
>tr|A0A0C2ZKS2|A0A0C2ZKS2_9PROT NAD-dependent deacetylase OS=Sulfurovum sp. FS06-10 GN=KU29_05100 PE=4 SV=1
----------------------------------------EKIVIFSGAGISAESGISTFRDAGGLWDEYKIEEICTAGCLSWNREKTIEFYNKRRVQLA
--EVEPNYAHKAIATLKEKYPHEIAVITQNVDDLFERAGCQDVIHLHGYMTNIRCEQCGLY------DE---VCGKCNA--SMRPDIIFFHERAPMYEEK
MK---YCEFLVVIGTSGNVIYMDDYAKKANY--SILNNLEPSSAINT-KYSKVIYKKASSAIDEIASEIEIFLL-----
>tr|T0KF33|T0KF33_9HELI Uncharacterized protein OS=Sulfurimonas sp. AST-10 GN=M947_09680 PE=4 SV=1
----------------------------------------AKVVILSGAGISAESGISTFRDSEGLWEHYDIKDICTAGCLETNRETTIEFYDKRRLDLA
--DKEPNRAHRVIARLKAKYKDDIAIITQNVDDLFEKAGIEDIVHLHGYLTKVECEKCGLY---K-QDSF-GKCPTCASG-KIRPFIVMFGEAAPMYANQ
EIDD--CELLVVIGTSGNVIAVDILSSYVDRT----ILNNLE--------PKVLYKKATEAIDEIASEIEIFLE-----
>tr|V2PYF4|V2PYF4_9BACT Uncharacterized protein OS=Mucispirillum schaedleri ASF457 GN=N508_01612 PE=4 SV=1
----------------------------------------AKILFFSGAGLSADSGLGVFR--NGLWDKYDINKVCNIVTWRANYNMVHEFYSKRRCQYV
--DAEPNKMHKVIAELQNKYGEEVVVITQNIDNLLEKAGCRKVMHVHGHINYIHCTECLN----EYKP---LKCEKCGSV-EFKPSIIFFGEQAPKYYQA
FAGLEHCDGA-VIGTEGSVIPIAQILGTKTNGVRLLCNLDKSPYIDD-FFDEVIYERAELASEKVSAFAENILR-----
>tr|C3XIH7|C3XIH7_9HELI Uncharacterized protein OS=Helicobacter bilis ATCC 43879 GN=HRAG_01852 PE=4 SV=1
----------------------------------------KRVMIFSGAGLSAESGLRTFRDNDGLWEEFDIMEVCSASGFAKDRKKVLDFYDKRRIQLG
--EVNPNAAHKMIARLKANYPQEVVVITQNVDDLLERAGCKNVIHLHGFLPEVRCELCETY-----KL----ICESCGEE-SLRHNIVMFSEYAPNYARE
LERESENSLFVCIGTSGEVLNVAQFSQCAKK--SVLNNLES-SW-FD-CFNMCFIESAVSAAPKIERLVGEFIE-----
>tr|V8CF52|V8CF52_9HELI Uncharacterized protein OS=Helicobacter canis NCTC 12740 GN=HMPREF2087_01568 PE=4 SV=1
----------------------------------------KRVMIFSGAGLSAESGLRTFRDNDGLWEEFDIMEVCSARGFAKDRQKVLDFYDQRRIQLG
--QVAPNVAHKMIAKLKEKYPQEIVVITQNVDDLLERASCKDVLHLHGFLPEVRCESCGEY-----SS----VCGVCGEQ-SLRHNIVMFSEYAPNYASE
LERAAEESLFVCIGTSGEVLNVAQFTLYAKQ--SILNNLES-SH-LD-YFDVRFIEPAGTAAPKIKDLVEGFLR-----
>tr|A0A099TJF0|A0A099TJF0_9HELI NAD-dependent deacetylase OS=Helicobacter sp. MIT 05-5293 GN=LS68_06630 PE=4 SV=1
----------------------------------------KRVMIFSGAGLSAESGLRTFRDSDGLWEEFDVMQVCSVKGFAKDRKKVLDFFDKRRIQLG
--EVSPNAAHRMIADLKEHYPKEVIVITQNVDDLLERAGCKDVIHLHGFLPEVYCESCKEY-----KL----TCQKCGKK-SLRHNIVMFGEYAPYYANE
LEKVA-NGLFVCIGTSGEVLNVAQFTRYAGK--SVLNNLES-SW-FD-YFDVCFIESAVNAAPKIRKLVEEFIQ-----
>tr|R5J9H8|R5J9H8_9BACE Uncharacterized protein OS=Bacteroides sp. CAG:189 GN=BN523_03215 PE=4 SV=1
----------------------------------------CKLVFYTGAGMSRESGLPTFRGKGGLWDTLNIEAVAARSSWYCGRQRMLDFFNLIRSLIM
--KKGPNEGHYIIAELEDEY--EVTVITQNGDDFHERAGSTNVIHLHGEALKNASTLHPYI---N-DIHI-D-KAPDGS--QLRPYVIFFNEDIELRLAS
VEATKQANVFIVVGSTMLVYPAAELLKMIPPKC-ELYIIDPS---------IHIQSGASLGLQQLKATLKLK-------
>tr|F6DBT2|F6DBT2_THICA Silent information regulator protein Sir2 OS=Thioalkalimicrobium cyclicum (strain DSM 14477 / JCM 11371 / ALM1) GN=Thicy_0545 P
----------------------------------------PKVIIFTGAGLSAESGLSTFRS-VGLWNNHPISEVCNEATWQANYAKVHAFYNDLRSQLE
--RAEPNPAHHAIARLQQQLGQD-VVITQNVDNLLERAGVSDVLHLHGLLTQMHCTQCEK----GYQPFNQQACCYCGHKDTIKPNIVFFGGRAPNYLSA
LSGIYHPDSVIVSGTQGNVVPIDEHLAQAC--GKVLNNLAPSDNINE-SYDQVYFEPASQAWLKIEAYVQQNWL-----
>tr|V5PLK2|V5PLK2_9BURK Uncharacterized protein OS=Pandoraea pnomenusa 3kgm GN=U875_00820 PE=4 SV=1
----------------------------------------PRLYVFSGAGLSAESGIPTFR--NGIWTQENLDEVCNFLNWRKNREAVFRFYNERIAEKR
--DARPNEAHAILAAWQNTWGKDVRLVTQNVDDMLERAGALHVTHLHGDMHSLLCTCCDL----LE--YRETACPRCGEVEAVKPGIVFFHEEAPEYVRM
QLEMTDDDLYVAIGTAFQIVPPETMLPRSRWRQNFLI--DPEPR-RT-FFGCVEPESATVGLRNLESCINALMR-----
>tr|A0A0A6Q3X8|A0A0A6Q3X8_9BURK NAD-dependent deacetylase OS=Burkholderia sacchari GN=NH14_28795 PE=4 SV=1
----------------------------------------PRLYVFSGAGLSAESGISTFR--DGIWTHTSIDEVCNYHTWRRNRPAVFRFYNQRIAECS
--GARPNDAHRLLAQWQNTWGTEVHLVTQNIDDMLEQAGARQVTHLHGDMISLLCTDCDY----AK--LDGAACPSCGQVESVKPGVVFFNEAAPEYQRI
QQAMTDDDLFIAVGTAFEVIPPERLLPPTRYGRNMLV--DPAPQ-RT-FFGVVEQEPATVGLSKLEPAIERMME-----
>tr|A0A038H3W3|A0A038H3W3_9BURK NAD-dependent deacetylase OS=Burkholderia jiangsuensis GN=BG58_12675 PE=4 SV=1
----------------------------------------PRLYVFSGAGLSAESGLSTFR--DGIWTRNSVDEVCNIRTWRKNRQAVFRFYNDRIREKH
--GAEPNAAHKLLAKWQNKWGAEVQLLTQNVDDLLEKAGATSVIHLHGDLNSLLCTACDL----LY--FDAAACPICGNHEGVKPGVVFFGEAAPAYLRL
QAEMRACDLFLAIGSAFEVVPPEAMLPWDRQNENFLL--DPSPN-RR-MFGVVEAQPATTGLQHLEEHIAGLMK-----
>tr|A0A0P0KU55|A0A0P0KU55_9BURK NAD-dependent deacetylase OS=Burkholderia plantarii GN=bpln_2g10210 PE=4 SV=1
----------------------------------------PRLYVFSGAGLSAESGIPTFR--DGIWSSANLDKVCNFLTWRRNREAVFAFYNARIAEKR
--DAVPNDAHRMLAAWQDAWGTGVRLVTQNIDDLLERAGARHVVHLHGDVHSLLCTACDC----EH--YRDTACPACGEVEGVKPGVVFFNEAAPEYARM
QLEMTERDLFVAIGTAFQVVGPESLLPRERRLGNFLV--DPAPS-RP-CFGTVEAVSASVGLRNLQARIEALMA-----
>tr|A0A0P6TLR1|A0A0P6TLR1_9BURK NAD-dependent deacetylase OS=Burkholderia multivorans GN=BMUNKI379_13775 PE=4 SV=1
----------------------------------------PRLYVFSGAGLSAESGIPTFR--GGIWSQESIDEVCNFLTWRRNREAVFRFYNERIAEKR
--DARPNDAHRILASWQAMWGPGVRLITQNIDDLLEQAGALHVTHLHGDMHSMLCTACDL----EN--YRDTVCPRCGTAETVKPGVVFFQEAAPEYVRM
QHDMTDDDVFIAIGTAFEVISPEAMLPRARWCRNFLV--DPEPR-RT-FFGHVESKPATVGLRNLESRIHALMT-----
>tr|K4F6K0|K4F6K0_9CAUD Putative Sir2-like protein OS=Cronobacter phage vB_CsaM_GAP32 GN=GAP32_119 PE=4 SV=1
----------------------------------------PRLIFCTGAGLSKESGIQTFRD-EGLWDDVSIDEVCNIATFHINYNKIHNFYNKMRTGLV
--NYEPNAGHHFIAEMQKKYGDEVMHITANVDDLIERAGGS-AMHVHGFLTEVIEPYSTNV---GYTEFT---TPG---V-LSKPNIVMFGERKQIYDKV
LDSVTARDTFIIVGSSDTVIPWSVYAGVA---TAPVVNINPEVHKND-LFTYNLYRPFTETLDTVEEFISQRMD-----
>tr|L7TPF2|L7TPF2_9CAUD Putative Sir2-like protein OS=Escherichia phage PBECO 4 PE=4 SV=1
----------------------------------------KRLLIISGAGLSVESGMEPFRF-DGLWDTFKINDVCNIASLTTKYHVVHSFYNTLRVKLG
--QCEPNAMHYFIKSLEDQYGDCFLHMTSNMDDLYTRIGGH-ELKLHGNLCEVIENYSINV---GYEPYI---KHD---V-FAKPNVVMIGERLPIYENV
LKSLNENDTVIVIGSSDTVLVWSRLAAAL---P-YSVNVNIRKNDND-LFNEKVIKPATKAIPHLETIIKERMK-----
>tr|H6X4V9|H6X4V9_9CAUD Putative Sir2-like protein OS=Enterobacteria phage vB_KleM-RaK2 GN=RaK2_00502 PE=4 SV=1
----------------------------------------KRLLIISGNGLSMDSGFDLYDI-----DNFQINDVCNIASLGTKYHVVHSYYNTLRVKLK
--DIEPNEMHYYIKSLQDEYGDNFLHMTSNVDDLYTRIGGT-ELKLHGNIKEVIENYTADI---GYEPYI---CSG---I-FSKPGVTLIGEKIPIYEEI
LKSLNENDTVVVIGSSDSVLKWSHLIN-E---K-YTVLINIRKNEND-RFNERIYKSCSKSVLDLSGIISKRMV-----
>tr|V6RWE1|V6RWE1_9FLAO NAD-dependent deacetylase OS=Flavobacterium cauense R2A-7 GN=FCR2A7T_27780 PE=3 SV=1
----------------------------------GFKKMKKKLVILSGAGMSAESGIKTFRDADGLWEGHDIMEVASPIGWNKNPELVLDFYNKRRAQLF
--EVQPNRGHEIIAEMEDQFD--IHVITQNVDDLHERAGSTKVLHLHGELLKVRSIANNHILDWKTDLNLGDTDKH---GHQLRPHIVWFGEAVPAIDEA
IEIVETADYLIVIGTSLQVYPAAGLMNYAKQ-QVPVYYIDLKPATIYPNPLEVIPMSASEGMEFVKGRL----------
>tr|G8XB34|G8XB34_FLACA Silent information regulator protein Sir2 OS=Flavobacterium columnare (strain ATCC 49512 / CIP 103533 / TG 44/87) GN=FCOL_05885
--------------------------------------MKKKLVILTGAGMSAESGISTFRDSNGLWENHDIKEVASPEGWRKNPALVLDFYNKRRAQLK
--EVTPNRGHEIIAELEQKFD--VQIITQNVDNLHERAGSSKILHLHGELTKVRSTENDYIINWSEDLHIGDMAPD---GSQLRPHIVWFGEAVPGINQA
IPMLEKADILIIIGTSLQVYPAAGLMHYTRT-DTPIYYIDPKPASVNPNPIEIIPLSASEGMKNLVERG----------
>tr|A0A0A2MXF1|A0A0A2MXF1_9FLAO NAD-dependent deacetylase OS=Flavobacterium enshiense DK69 GN=Q767_04855 PE=3 SV=1
--------------------------------------MKKKLVILSGAGMSAESGIKTFRDADGLWEGHDIMEVASPIGWDKNPELVLDFYNKRRAQLL
--EVQPNRGHEIIAELENQFD--VHVITQNVDDLHERAGSSNVLHLHGELLKVRSVANNHIIDWKTDLYLGDTDKH---GHQLRPHIVWFGEAVPAIDEA
IEIVQDADILIVIGTSLQVYPAAGLINFANN-EVPIYYIDPKPATMYINPVTVIPMSASEGMEKIMSDS----------
>tr|A0A0A2M614|A0A0A2M614_9FLAO NAD-dependent deacetylase OS=Flavobacterium suncheonense GH29-5 = DSM 17707 GN=Q764_12515 PE=3 SV=1
--------------------------------------MKKKLVILSGAGMSAESGIKTFRDADGLWEGHDIMEVASPIGWSKNSGLVLDFYNKRRAQLL
--EVQPNRGHEIIAEMEHQFD--VHIITQNVDDLHERAGSTKVLHLHGELLKVRSTVNNYILDWKSDLKLGDTDAH---GHQLRPHIVWFGEAVPAIDEA
IDIVEGANYLIVIGTSLQVYPAAGLINYTNP-DIPIYYIDPKPATMYANPVTVIPMSASDGMEFVKKEL----------
>tr|H8KVJ8|H8KVJ8_SOLCM NAD-dependent protein deacetylase, SIR2 family OS=Solitalea canadensis (strain ATCC 29591 / DSM 3403 / NBRC 15130 / NCIMB 12057
---------------------------------------MKKLVILTGAGISAESGLKTFRDSDGLWEGYDINEVATPEGWRRNPELVQDFYNMRRKAVV
--EAQPNAAHYALADLEKYFE--VVIITQNIDNLHEKAGSTNVLHLHGIITKSQSSLDNLTY--GYEIKMGEKCEK---GSQLRPHVVWFGEAVPMIDPA
AKHCSKADYFAVIGTSLQVYPAAGLMNFVPF-KIPKFLVDPNAPDV-KNGVTIINEKASIGVPLMAEQL----------
>tr|A3J5K0|A3J5K0_9FLAO NAD-dependent deacetylase OS=Flavobacteria bacterium BAL38 GN=FBBAL38_09579 PE=3 SV=1
---------------------------------------MKKIVVLTGAGISAESGIKTFRDAYGLWEGHDIMEVASPIGWKKNPELVLDFYNKRRAQLL
--TVRPNKAHEILAELEEHFD--IHIITQNVDDLHERAGSNKVIHLHGELLKVRSISNNFVLDWKHDLNLGDFDLD---GNQLRPHIVWFGEDVPMIENA
IDIVETADVLIIIGTSLQVYPAAGLMNYVEN-HVPVFYIDPKPATIYPNELKVLPLTAVEGMKIVKEEL----------
>tr|A0A0A2LRP1|A0A0A2LRP1_9FLAO NAD-dependent deacetylase OS=Flavobacterium beibuense F44-8 GN=Q763_05790 PE=3 SV=1
--------------------------------------MKKKLVVLSGAGVSAESGIKTFRDAGGLWEGHNVMEVASPEGWRKNPALVLDFYNKRRQQLF
--EVVPNKAHTIIAELENHFD--VTVITQNVDDLHERAGSTKVLHLHGELLKARSVNNFDIVECTGDINEGDLHTD---GHQLRPHIVWFGEAVPAIPEA
INIVEKADYLIIIGTSLQVYPAAGLIDYAKQ-TIPIYYIDPNPGSIPHYYIENIKLTGSEGMELVYEKL----------
>tr|A0A0C1X522|A0A0C1X522_9CHRO NAD-dependent deacetylase OS=Aphanocapsa montana BDHKU210001 GN=QP59_06595 PE=3 SV=1
---------------------------------------MDKLVVLTGAGMSAESGIKTFRDDDGLWEGHDVMEVASPQGWRKNPELVLDFYNQRRRQLH
--EVEPNSGHEALSALEDIFS--TTVVTQNVDDLHERGGSSNVLHLHGELFKVRSTQHEL--EWKEDLNIGHTCEK---GHQLRPHIVWFGEAVPMLEEA
ALEVLDADIILIIGSSMQVYPAAGLVGFAQK-ARKIYYVDPNPSINYIADLKVIDAPATQGVPAVVEDL----------
>tr|A0A0F2NRH5|A0A0F2NRH5_9FLAO NAD-dependent deacetylase OS=Flavobacteriales bacterium BRH_c54 GN=VR77_11390 PE=3 SV=1
--------------------------------------MKQKIVVFTGAGISAESGIQTFRDGDGLWENHDIQQVATPEAWNENPRLVLDFYNERRKQVL
--KAKPNEAHQSLVLLEENFD--VQIITQNIDDLHERAGSKKVLHLHGEILKARSTFDEL-Y--KPTIKLGDKCPK---GFQLRPHVVWFGEPVPNMLEA
ANWCDDAKFLIVIGTSLNVYPAANILNFVST-NCVKYLIDPQIPKSFENNIKIIQKKAGEGVTELVNQL----------
>tr|K1HT19|K1HT19_MYROD Uncharacterized protein OS=Myroides odoratus CIP 103059 GN=HMPREF9716_00857 PE=3 SV=1
--------------------------------------MEKRLVVLSGAGMSAESGIKTFRDADGLWEGHDIMEVASPIGWAKNKEMVLKFYNDRRRQLL
--TCEPNAAHRAIAELQQHFK--TTIITQNVDDLHERAGSKDVIHLHGELLKVRSEVNQL--SWTTDLTALDHNEH---GHGLRPHIVWFGEMVPELERA
IPYVEEADVILIIGTSLQVYPAASLLDFAKP-DVLVYYIDLHPASTKHHKIEVIAEKASVGMQQIHESL----------
>tr|G2Z154|G2Z154_FLABF NAD-dependent deacetylase OS=Flavobacterium branchiophilum (strain FL-15) GN=npdA PE=3 SV=1
---------------------------------------MKKIVVLTGAGISAESGIKTFRDSDGMWENHNVMDVATPEGWQKNPKLVLDFYNQRRKQLN
--SVFPNKAHSILKDLEDHFD--VEIITQNVDNLHEKAGSSAIIHLHGMLTKVRSTKHNVVLDWHDDLNWGDTDSN---GHQLRPHIVWFGEAVPMIEKA
ALIVEKADILVIIGTSLQVYPAASLMQYASA-NTTIYYIDPNPAEMYPNDVYIIKEKASVGMEKLYKIL----------
>tr|A0A0N7K8L8|A0A0N7K8L8_FLAPS NAD-dependent deacetylase OS=Flavobacterium psychrophilum GN=AMR72_04220 PE=4 SV=1
---------------------------------------MKKLVILSGAGMSAESGIKTFRDAGGLWEGHDVMEVASPEGWRKNQALVLDFYNKRRQQLF
--EVQPNQGHIIAAELEKDFD--VHIITQNVDDLHERAGSTNVLHLHGELLKARSIHNFDIVDWKTDINTGDLHTD---GHQLRPHIVWFGEAVPAIADA
IDIIEDADYVIIVGTSMQVYPAAGLIEYAQR-DTLLFYIDPNPASIPKNALEVIPMTASEGMAVVRERL----------
>tr|A0A084TJA3|A0A084TJA3_9FLAO NAD-dependent deacetylase OS=Mangrovimonas yunxiaonensis GN=IA57_10070 PE=3 SV=1
---------------------------------------MKHLVVLTGAGMSAESGIKTFRDANGLWEGHDVMEVASPIGFAKNPELVLDFYNQRRRQLL
--SVSPNLAHRALADLETTYQ--VSIITQNVDDLHERAGSTNVLHLHGELLKARSTYNTDVFPWKADIKLGDLCQK---GHQIRPHIVWFGEAVPLIDEA
INICQTADILVIIGTSLQVYPAASLMAYTPK-SARVYYIDPHPA--PGNHIQLIAEKATTGMQKLTALI----------
>tr|A0A0A2LZK6|A0A0A2LZK6_9FLAO NAD-dependent deacetylase OS=Flavobacterium rivuli WB 3.3-2 = DSM 21788 GN=Q765_15675 PE=3 SV=1
---------------------------------------MKKLVILSGAGISAESGVATFRDSGGLWEGHDVMDVASPEGWRKNPSLVLDFYNKRRRQLF
--EVEPNRAHFIAAELEKDFD--VTIITQNVDDLHERAGSSKVIHLHGELLKARSVNNEDIIDLTGDINLGDLHTD---GHQLRPHIVWFGEAVPAIEEA
AYITEQADYVIVIGTSLQVYPAAGLIDFTKR-TTPIFYIDPKPASIPKNPLEVVPMVASEGMEVVAGRL----------
>tr|U5CIP2|U5CIP2_9PORP Uncharacterized protein OS=Coprobacter fastidiosus NSB1 GN=NSB1T_14325 PE=3 SV=1
---------------------------------------MKKLIVLTGAGMSAESGLSTFRSSNGLWENHRVEDVATPEGWYRNPELVLDFYNGLRKTLI
--KSEPNAGHKKLAELESDYE--VHIITQNVDNLHERAGSSHVIHLHGELMKVRSVRN-LIYPEHCEIHLGDKAED---GGQLRPHIVWFGEAVPMIEPA
IELVSEADIFVIIGTSLNVYPAAGLLNYVRA-NVPIYLIDPNDVHDPGRVSHFIRKGASEGMRELIEIL----------
>tr|F0S5X8|F0S5X8_PSESL Silent information regulator protein Sir2 OS=Pseudopedobacter saltans (strain ATCC 51119 / DSM 12145 / JCM 21818 / LMG 10337 / 
---------------------------------------MKNIVVLTGAGISAESGIATFRDQNGLWEKHRIEDVATPEGWLKNPELVLNFYNLRRQQAK
--TVKPNYAHIKLKELEKDFN--VHIVTQNVDYLHEEAGSSNIIKLHGSLFSRCSDRNKTIK--FDDMIFGDLAPD---GGFWRPDIVWFGEAVPEIENA
IPIFRKADACIIIGTSMQVYPAAGLTQYLPH-DSEIIILDVNTPPANRAKIHYVTKKATEVLMRLLGCL----------
>tr|W8EYM3|W8EYM3_9BACT NAD-dependent deacetylase OS=Hymenobacter swuensis DY53 GN=Hsw_2624 PE=3 SV=1
--------------------------------------MKKKLVALTGAGISAESGLATFRASDGLWENHRIEDVATPEGWAVNPALVLEFYNQRRGAAR
--AAQPNAGHLALAELERDFE--VVIVTQNVDDLHERAGSSRVIHLHGKLLEARSSRHELVY--SDRIELGQLCEK---GHQLRPNIVWFGEAVPLLELA
AHEAATADVFLVVGTSLQVYPAAGLVDYVRR-GTPIYIIDPHRPPVNRPNQHFITEPATIGVAQVAAEL----------
>tr|A0A0L8AN44|A0A0L8AN44_9BACT NAD-dependent deacetylase OS=Roseivirga sp. D-25 GN=OB69_04900 PE=3 SV=1
---------------------------------------MKKLVVLSGAGISAESGLKTFRDADGLWEGHSVTEVATPEAWRKNPELVLEFYNQRRKQAL
--ETKPNRAHEILKELEAHFE--VSIITQNVDNFHEQAGSSQVIHLHGQLFQSRSEKNSLIY--HWELKLGDLCEK---GHQLRPNIVWFGEAVPMMDVA
AEITEQADILVIVGTSLVVYPAASLVHYVGN-HAPVFIVDPHQPEISRSNRHFIQEKATTGMALLKEIL----------
>tr|A0A0M4HK46|A0A0M4HK46_9BACT NAD-dependent deacetylase OS=Hymenobacter sp. DG25A GN=AM218_07600 PE=3 SV=1
--------------------------------------MKKKLVALTGAGISAESGLATFRGFDGLWEGHRVEDVASPEGWARNPELVLDFYNQRRAAAR
--AAQPNAGHKALVALEQAYE--VVIITQNVDELHERAGSSHVIHLHGKLFEARSSRHELVY--SDRIELGELCEK---GSQLRPNIVWFGEAVPLMERA
MEEAATADVFAVIGTSLQVYPAANLVHYAPT-NCPLYIIDPHQPPLTRRNLHFITEPATTGVPRLAAQL----------
>tr|W0EVW1|W0EVW1_9SPHI NAD-dependent deacetylase OS=Niabella soli DSM 19437 GN=NIASO_06880 PE=3 SV=1
-------------------------------------MKLKKLVVLTGAGISAESGLRTFRDSDGLWEGYDVTEVASPEGWRHDPALVLDFYNMRRKNVA
--DAQPNAAHLGLAELEKYFE--VQIVTQNIDDLHERAGSANVLHLHGEIFKMRSDRSKPSY---NAIHLGDKAPD---GGQLRPDIVWFGEPVPMIGPA
ARLAADADIFVVIGTSLVVYPAAGLIEEVPA-SVPKYIIDKTIPQIRIPGLVTIEMPATTGVAELRRLL----------
>tr|G8TFH8|G8TFH8_NIAKG NAD-dependent deacetylase OS=Niastella koreensis (strain DSM 17620 / KACC 11465 / GR20-10) GN=Niako_2054 PE=3 SV=1
-------------------------------------MSKKKLVVLSGAGISAESGLKTFRDSDGLWEGYNVTDVATPRAWKKDPALVLEFYNQRRKNVL
--DAQPNAAHLGLAKLQDDFD--VTIITQNIDDLHERAGSKKVLHLHGEIFKMRSEHDSLVY---GDINLGDKAGD---GAQLRPHIVWFEEPVPLIQQA
VPVVLSADIFVVIGTSLVVYPAAGLVNYAPM-EIPKYVIDKVIPSTNVYNVTNIEKPATQGIQDLMELL----------
>tr|C7PUW8|C7PUW8_CHIPD Silent information regulator protein Sir2 OS=Chitinophaga pinensis (strain ATCC 43595 / DSM 2588 / NCIB 11800 / UQM 2034) GN=Cp
--------------------------------------MKPRLVVLTGAGISAESGLRTFRDSDGLWEGYNVYEVASPQGWQKDPQLVLDFYNQRRRDIK
--AAMPNAAHLGLAALQEQFD--VEIITQNIDDLHERAGSKKVLHLHGEIFSMRSVLDHRKY---SDINLGDKAAD---GGQLRPDIVWFGEAVPKIVEA
AAVVMTADVFAVIGTSLVVYPAAGLVDYLPE-GTPAFVIDRKLPQMPMTNLMKIEKPATEGIADMIKAL----------
>tr|A0A0C1KVU9|A0A0C1KVU9_9SPHI NAD-dependent deacetylase OS=Flavihumibacter sp. ZG627 GN=HY58_06660 PE=3 SV=1
---------------------------------------MKKIVVLTGAGISAESGLKTFRDSDGLWEGYDIEEVATPRAWRRDPKLVLEFYNMRRRNVL
--EAVPNAAHNALADLQNDFD--VHIITQNIDDLHERAGSKKVLHLHGEILSMRSEHDFLVS---TDMEFGALAPD---GYAWRPDIVWFEEPVPAIGEA
VPLVRSADIFIVVGTSLLVYPAAGLVDFAPY-DCPKFIVDKKIPSSGIHHLVKIEAPASEGMPMLAEKL----------
>tr|R5ASL7|R5ASL7_9BACT Silent information regulator protein Sir2 OS=Prevotella sp. CAG:1031 GN=BN456_01160 PE=4 SV=1
--------------------------------------MRKKLVISTGAGMSAESGINTFRDHDGLWENYDVMDVASADGFRRNPKLIHDFYNARRRELI
--KANPNAGHLGLVELEKWYD--TYIITQNVDNLHERAGSKNVLHLHGELMKIRSLAHERVYPGNLETSVETVDRY---GDHVRPHIVFFQEAVPNIEPA
IELASQAEIFVVIGTSMVVYPAAALLNYVRP-GVPVYYIDPNPAAVP-SNVTVLKEPATRGVADLVELL----------
>tr|R7IYE0|R7IYE0_9BACT Uncharacterized protein OS=Prevotella sp. CAG:873 GN=BN799_00050 PE=4 SV=1
---------------------------------------MKKLVVSTGAGMSAESGIATFRDAGGLWENYPVMDVASADGFARNPALIHKFYNERRKELF
--AAEPNAGHRGLVDLEKDFD--VRIITQNVDNLHERAGSSNVLHLHGQLDYVRALDNKLRWPEDPETTVDTVI-E---GHHVRPDIVFFQEAVPNFDPA
TRIVAEADIFVIIGTSLVVYPAAALINYVRR-GVPVFYIDPRPSDVP-EGVHIIRTGAGEGVARLAEIL----------
>tr|R7EV17|R7EV17_9BACT NAD-dependent deacetylase OS=Prevotella sp. CAG:485 GN=BN677_00933 PE=4 SV=1
--------------------------------------MKKKLVISTGAGMSAESGIPTFRDVGGLWENYPVMDVCSADGFRRNPALVHQFYNERRRQYM
--GCMPNAAHKALVELERDYD--VYVITQNVDDLHERAGSTRVLHLHGEIMKMRSVSNDYIEADHLDTTPQTRGRN---GDLMRPHIVFFQEPVPNIEKA
IEIARQADIFVVIGTSLVVYPAASLIQFVRP-GTPIYYIDPHPGDVSIPGVTVIRATATEGVRELQKLL----------
>tr|A0A072N1S6|A0A072N1S6_9ALTE NAD-dependent protein deacetylase of SIR2 family OS=Marinobacter sp. AK21 GN=D777_01835 PE=4 SV=1
--------------------------------------------MLTGAGISAESGLSTFRDNGGLWEQHSVYDVATPEAFARNQELVLRFYNERRRQLQ
--EAEPNPAHRLLASLEERFR--VTVVTQNVDNLHERGGSSNVIHLHGELTKARSSGYDLVY--YRDINPGDTCER---GAQLRPHIVWFGEEVPMLAAA
ADVVSTADHLLIVGTSLQVYPAAGLVHEVGL-DVPITVIDPGEPA-S-SRANVIRKGASEGLADWIAQL----------
>tr|M7CV73|M7CV73_9ALTE Silent information regulator protein Sir2 OS=Marinobacter santoriniensis NKSG1 GN=MSNKSG1_09513 PE=3 SV=1
--------------------------------------MQDHIVVLTGAGISAESGLSTFRDNGGLWEQHSVYDVATPEAFQRNPELVLRFYNDRRHQLK
--SAIPNQAHRLLAELERRYR--VTIVTQNVDDLHERGGSSQVLHLHGELTKARSTGFELVY--YGDIKPGDRCER---GTQLRPHIVWFGEEVPMLDAA
AEVVRTADHLLIVGTSLQVYPAAGLVHEVGF-DVPITVIDPGEPA-S-SRARVIRKGASEGVADWVRSL----------
>tr|G6YUG1|G6YUG1_9ALTE Silent information regulator protein Sir2 OS=Marinobacter manganoxydans MnI7-9 GN=KYE_13245 PE=3 SV=1
--------------------------------------MQDHIVVLTGAGISAESGLSTFRDNGGLWEQHSVYDVATPEAFARNQELVLRFYNDRRRQLA
--SAQPNRAHQLLAELEQRYR--VTVVTQNVDDLHERGGASNVIHLHGELTKARSSKYELVY--YRDINPGDTCDR---GAQLRPHIVWFGEEVPMLDKA
AEVVRTADHLLIVGTSLQVYPAAGLVYEVDR-DVPITVIDPGEPA-S-SRARFIRKGAVEGVAEWVAHY----------
>tr|W5YHR8|W5YHR8_9ALTE NAD-dependent deacetylase OS=Marinobacter similis GN=AU14_06470 PE=3 SV=1
--------------------------------------MRDHIVVLTGAGISAESGLSTFRDNGGLWEEHSVYDVATPEAFARNQELVLRFYNDRRRQLE
--SAQPNQAHRLLAELESRYR--VTIVTQNVDDLHERGGSSNVIHLHGELTKARSSQHDLVY--YQDIQPGETCER---GAQLRPHIVWFGEEVPMLDAA
AEMVRTADYLLIVGTSLQVYPAAGLVYEVEP-GVPVTVVDPAEPP-S-SRARFIQKGACEGVADWIASL----------
>tr|A1U4H3|A1U4H3_MARHV Silent information regulator protein Sir2 OS=Marinobacter hydrocarbonoclasticus (strain ATCC 700491 / DSM 11845 / VT8) GN=Maqu_
--------------------------------------MQEHIVVLTGAGISAESGLSTFRDNGGLWEQHSVYDVATPEAFERNRDLVLRFYNERRRQLQ
--TVQPNPAHRLLAELESRFQ--VTVVTQNVDDLHERGGSSNVLHLHGELTKARSSAYDLIY--YNDINPGDTCDR---GAQLRPHIVWFGEEVPMLDAA
AEVVRTADQLLIVGTSLQVYPAAGLVYEVDI-DVPITVIDPGEPA-S-SRARVIRKGASEGVREWVSRY----------
>tr|W5YVB0|W5YVB0_9ALTE NAD-dependent deacetylase OS=Marinobacter salarius GN=AU15_00375 PE=3 SV=1
--------------------------------------MKDHIVVLSGAGMSAESGLSTFRDNGGLWEQHSVYDVATPEAFARNQELVLRFYNERRRQLK
--SAQPNDAHRLLAELEQHYR--VTIITQNVDNLHERGGSSNVIHLHGELTKARSSTHELIY--FNDIQPGDTCDR---GSQLRPHIVWFGEEVPMIEAA
AEIVPTADHLLIVGTSLQVYPAAGLVDLVNF-DVPVTVIDPGEPA-S-SRAKVIRKGAGEGVAEWMKGL----------
>tr|A0A0H4I2K9|A0A0H4I2K9_9ALTE NAD-dependent deacetylase OS=Marinobacter psychrophilus GN=ABA45_13150 PE=3 SV=1
--------------------------------------MKRHIVVLSGAGISAESGLATFRDNDGLWEKHNVNDVATPEAFQRDPGLVLRFYNERRRQLA
--NTQPNRAHRLLAELERSYR--VTIVTQNVDDLHERGGSTQVLHLHGELTKARSSKNRAIH--YRDIRLGERSQD---SSQLRPHIVWFGEEVPMLEVA
IDIVRSADDLLIVGTSLKVYPAAGLVHEVER-DVPITVINPVTPTGR-SRARFIQKSAVEGVAEWVNSF----------
>tr|A0A0Q5SYD8|A0A0Q5SYD8_9BACT NAD-dependent deacylase OS=Dyadobacter sp. Leaf189 GN=ASG33_17095 PE=4 SV=1
---------------------------------------MKKLVVLSGAGISAESGISTFRDNGGLWDNYRIEDVATPEAWSRNQELVLDFYNQRRKQAY
--EVKPNAAHYALVELEKHFD--VSIITQNVDNLHEVAGSSNVIHLHGELFKSRSTKNELVY--SWELKTGDLCEL---GSQLRPHIVWFGEEVPMMEKA
IDVTETADIFLVIGTSLAVYPAAGLVHYVRP-GQPIYIIDPAQPDIRKPNMFFIQEKASTGMEVLTKQY----------
>tr|H7FTB2|H7FTB2_9FLAO NAD-dependent protein deacetylase of SIR2 family OS=Flavobacterium frigoris PS1 GN=HJ01_01888 PE=3 SV=1
-------------------------------------MMKKKLVVLTGAGISAESGIKTFRDSDGLWEGHNVLDVATPEGWYKNPALVMDFYNQRRKQLK
--EVNPNLGHQILAELESHFE--VQIITQNVDDLHERAGSTNVLHLHGELLKVRSTVNNFILDWKEDLNFGDFDTD---QNQLRPHIVWFGEEVPALDEA
ISLTETADYFAVIGTSLQVYPAAGLIDFTNS-KTPIYYIDPKPIKIPRNPLQVFPEVASEGMKLLKKEL----------
>tr|A0A085EIU3|A0A085EIU3_9FLAO Uncharacterized protein OS=Flavobacterium sp. EM1308 GN=FEM08_21060 PE=3 SV=1
--------------------------------------MKKKLVVLTGAGISAESGIKTFRDSDGLWEGHNVMDVATPDGWRKNPELVLDFYNQKRKQLK
--EVQPNLGHQILAELENYFD--VYIITQNVDDLHERAGSTNITHLHGELLKVRSTKNNQILDWQDDLLIGDKDQN---GHQLRPHIVWFGEQVPALEDA
ITITEQADFFAVIGTSLQVYPAAGLIDFTKK-GTPIYYIDPKPIKIPKNPLEVIPNVASEGVQIMKDKL----------
>tr|A0A0C1CFU1|A0A0C1CFU1_9FLAO NAD-dependent deacetylase OS=Flavobacterium sp. AED GN=OA85_16570 PE=3 SV=1
--------------------------------------MKKKLVVLTGAGISAESGIKTFRDSDGLWEGHNVMDVATPEGWHKNPALVLDFYNQRRKQLK
--EVEPNLGHQILAELENEFE--VYIITQNVDDLHERAGSSNVLHLHGELLKVRSTKNNYILDWQDDLNFGDLDDN---KNQLRPHIVWFGEEVPALDEA
ITITQSADYFAVIGTSLQVYPAAGLIDFTAR-ETPIFYIDPKPIKIPRNPLDVIPEVASEGMKTLKKKL----------
>tr|A0A075S8I3|A0A075S8I3_FLAPS NAD-dependent deacetylase OS=Flavobacterium psychrophilum GN=FPSM_00996 PE=3 SV=1
--------------------------------------MKKKLVILTGAGISAESGIKTFRDSGGLWEGHNVEDVATPQGWHKNPTLVLDFYNKRRQELK
--TVKPNEAHLILADLENDFD--IQIITQNVDNLHERAGSKNVLHLHGELLKVRSTKNNYILDWSENLHLGDFDDK---KNQLRPHIVWFGEDVPALEYA
VELVQLADILIIIGTSLQVYPAASLMHFAPE-DCLVYYIDPNPANVSPQNFKIIEALASKGMQILQKEL----------
>tr|J9GT41|J9GT41_9ZZZZ Transcriptional regulator, Sir2 family OS=gut metagenome GN=EVA_00144 PE=4 SV=1
--------------------------------------------------MSAESGIRTFRDADGLWEEYPVEQVATPEGYAANPQLVLDFYNQRRRQLL
--EVKPNRGHEILAELEQYFQ--VTILTQNVDNLHERAGSSQVIHLHGELTKVTSSRDACIRPEEYEVKIGDLAAD---GSQLRPYIVWFGEPVPMISMA
ARYAQEADIFLIIGTSMNVYPAAGLLRYVPF-QVPVYLIDPKEVP-IGRPVQFLRKGASAGMEELKKMW----------
>tr|U6RBP2|U6RBP2_9BACE NAD-dependent deacetylase OS=Bacteroides massiliensis B84634 = Timone 84634 = DSM 17679 = JCM 13223 GN=HMPREF1534_03240 PE=3 SV
---------------------------------------MKNLVILTGAGMSAESGISTFRDAGGLWDQYPVEQVATPEGYVANPQLVIQFYNERRKQLL
--QVKPNRGHELVAELEKYFN--VTVITQNVDNLHERAGSSHVIHLHGELTKVTSTLQNYIKPEEFEVKIGDLAAD---GSQFRPFIVWFGESVPMIEKA
IEYVETADVFLIIGTSLNVYPAAGLLNYVPR-DVPVYLIDPKEVP-IDRKVYAIRKGASDGMEELKKIL----------
>tr|H6L786|H6L786_SAPGL NAD-dependent deacetylase OS=Saprospira grandis (strain Lewin) GN=SGRA_3962 PE=3 SV=1
------------------------------------MSEKLKVVILTGAGISAESGIQTFRDANGLWEGHDVMQVASPEGFAQNPALVLDFYNQRRAQLH
--EVAPNAGHLALKDLEAHFE--VAVITQNVDDLHERAGSSRVLHLHGELFKKRSSLDEN--PCKEDILLGQTCPK---GGQWRPHIVWFGEDVPMLGVA
AAWAELADIFIVVGTSMQVYPAAGLIHYVPK-ASPKFYVDPKPAQ--LDNLKVLAEPATTGLPALVAEL----------
>tr|A4CNH4|A4CNH4_ROBBH Uncharacterized protein OS=Robiginitalea biformata (strain ATCC BAA-864 / HTCC2501 / KCTC 12146) GN=RB2501_00156 PE=3 SV=1
---------------------------------------MKRLVVLSGAGMSADSGIRTFRDAGGLWEGHPVEQVATPEGFRQDPRRVLDFYNQRRRQLS
--EVAPNKGHLALAKMEQHYH--TTIVTQNVDDLHERAGSSRVLHLHGELLKARSTGPAR--PWFEDIVLGDTCPD---GFQLRPHIVWFGEEVPMLQRA
AEVTAQADVLIIVGTSMQVYPAAGLVHYKKE-GVPLYFVDPDPQMAPHGNLEIIRERASVGLPILANRL----------
>tr|K1LH36|K1LH36_9FLAO Uncharacterized protein OS=Bergeyella zoohelcum ATCC 43767 GN=HMPREF9699_01630 PE=3 SV=1
-----------------------------------MMKDKKTFVVLSGAGISAESGISTFRDANGLWENHSIEEVASIEGFNKNPALVLDFYNQRRAQLF
--SVAPNEAHHLLVTLEEDFD--VKIITQNVDDLHERAGSTQVLHLHGELRKVRPIDT---SPWKKDLLLGDVDER---GVQLRPHIVWFGEEVPMMEIA
MEWAAQADYFLVIGTSLQVYPAAGLIHFVPE-HAKVFSINPDENYMTHKYAIHFSEIASVGMKKMIASI----------
>tr|A0A0F5JGJ9|A0A0F5JGJ9_9PORP Uncharacterized protein OS=Parabacteroides gordonii MS-1 GN=HMPREF1536_02213 PE=3 SV=1
--------------------------------------MKKKLVILTGAGMSAESGISTFRDSDGLWEKYRVEDVATPEGFTANPELVLNFYNQRRRELL
--NTKPNAGHIGLAELEKDFE--VHIITQNIDNLHEQAGSTDVIHLHGELMKACSVRD-TTYPENPDIHIGDKDPH---GVQLRPFIVWFGEAVPMIDPA
IRMVESCDIFVVIGTSLNVYPAAGLLNYVRR-GQPIYLIDPKEVNTYN-DIHFIKSGASEGVKELSKIL----------
>tr|R7JFQ8|R7JFQ8_9PORP Transcriptional regulator OS=Parabacteroides sp. CAG:409 GN=BN646_02108 PE=3 SV=1
--------------------------------------MKKRLVVLTGAGMSAESGISTFRDSDGLWEKYRVEDVATPEGFQKDPELVLNFYNQRRRELL
--NTKPNAGHLGLAALEKDFD--VRIVTQNIDNLHERAGSTHVIHLHGELMKACSVRD-TTYPAHPDIHWGDKDPK---GVQLRPFIVWFGEAVPMIDPA
IREVEACDIFVIIGTSLNVYPAAGLLNYVRR-GQPIYLIDPKEVRTYD-DIVHLQCGASEGVKRLTEIL----------
>tr|K5ZRV7|K5ZRV7_9PORP Uncharacterized protein OS=Parabacteroides distasonis CL03T12C09 GN=HMPREF1075_03672 PE=3 SV=1
---------------------------------------MKKLVILTGAGMSAESGISTFRDSDGLWEKYRVEDVATPEGFAANPKLVLDFYNQRRRELL
--NTKPNAGHLGLAALEKDFD--VRIITQNIDNLHERAGSSHVIHLHGELMKACSVRD-TTYPENPDIHLGDKDLH---GNQLRPFVVWFGEAVPMIEPS
IKLVEDCDIFVIIGTSLNVYPAAGLLNYVRR-GQPIYLIDPKDVRTYN-DIEHIQAGASEGVKRLTELL----------
>tr|A0A0E4BD87|A0A0E4BD87_TANFO NAD-dependent deacetylase OS=Tannerella forsythia 3313 GN=TF3313_0847 PE=3 SV=1
---------------------------------------MKKIVILTGAGMSAESGISTFRDSNGLWENYRIEDVATPEGFMKNPQLVLDFYNHRRRELL
--NTQPNAGHRGLADLEKDFE--VHIITQNVDNLHEQAGSTHVTHLHGELMKSCSVKN-RPYPEQPDLHVGDKAPD---GGQLRPFIVWFGEPVPKIEEA
IRYVEDCDIFVVIGTSLNVYPAAGLLNYVRK-EQPIFLIDPKEVKAYS-DIEFIRYGASEGVKRLTERL----------
>tr|K6A1A7|K6A1A7_9PORP Uncharacterized protein OS=Parabacteroides merdae CL03T12C32 GN=HMPREF1060_02909 PE=3 SV=1
--------------------------------------MKKKLVVLTGAGMSAESGISTFRDSDGLWEKYRVEDVATPEGFAADPELVLNFYNQRRRELL
--NTKPNAGHIGLADLEQEFD--VHIITQNIDNLHERAGSSHVIHLHGELLKACSVRD-TTYPENPDLHIGDKDPH---GVQLRPFIVWFGEAVPMIDPA
IRLVEDCDIFVVIGTSLNVYPAAGLLNYVRH-GQPIYLIDPKEVKAHN-DIRFIRKGASEGVKELKELL----------
>tr|A0A010M7C0|A0A010M7C0_ACIBA Sir2 family protein OS=Acinetobacter baumannii 1578804 GN=J588_1886 PE=3 SV=1
---------------------------------------MTKLVVFSGAGMSAESGISTFRDSNGLWENYDIQQVATPEAWQRDPALVQRFYNERRKNIL
--EAKPNEAHQYIAKLQDYFD--VQVITQNIDDLHERAGSSNVLHLHGNIRLTKSSG-TQFYGWKLDLE-QDFCPD---GYPLRPHVVWFGEAVPAYDEA
IQLVQSADIFIVIGSTLSVYPVAALVHEISD-QCKAYYIDLNADHLRPHRYELLKMSATQGMHKLFENL----------
>tr|A0A062DMX4|A0A062DMX4_ACIBA Sir2 family protein OS=Acinetobacter baumannii 496487 GN=J524_1172 PE=4 SV=1
---------------------------------------MTKLVVFSGAGMSAESGISTFRDSNGLWENYDIQQVATPEAWERNPALVQRFYNERRKNIL
--EARPNEAHQYIAKLQDYYD--VQVITQNIDDLHERAGSQNVLHLHGNIRLAKSSG-TQFYGWKLDLE-QDFCPN---GYPLRPHVVWFGEAVPAYEEA
IRLVQSADIFIVIGSTLSVYPVAALVHEIPH-YSKAYYIDPQADHSRPPQYKLLTMTATEGMHELFQQL----------
>tr|A0A095Z9D3|A0A095Z9D3_9BURK NAD-dependent deacetylase OS=Oligella urethralis DNF00040 GN=HMPREF2130_05015 PE=3 SV=1
-------------------------------------MSKKKLVVLSGAGISAESGLKTFRDSDGLWEEHRVEDVATIDAFNRDPELVMRFYNLRRAQLN
--TVEPNAAHKILADLEDIFD--VQVITQNVDDLHERAGSSKVLHLHGELRKVRPVDSE--SQWLDDLQLGDVDER---GVQLRPHIVWFGEMVPAMQEA
AEIASSADLLLVIGTSMKVYPAAGLIDFIPP-HCELYVIDKGLENQFCHPDNFYQCGASEGMRQLAARL----------
>tr|U6RW43|U6RW43_9BACE NAD-dependent deacetylase OS=Bacteroides sp. HPS0048 GN=HMPREF1214_00336 PE=3 SV=1
---------------------------------------MKNLVILSGAGMSAESGISTFRDAGGLWDKYPVEQVATPEGYARDPELVIHFYNERRKQLL
--DVKPNRGHELLAELEKHFN--VTVITQNVDNLHERAGSTHVIHLHGELTKVCSSRDHYIKPEEYEVRMGDCARD---GSQLRPFIVWFGEAVPMIEAA
IDIVEKADVFVIIGTSMNVYPAAGLLNYVPR-TAEVYLIDPKPVD-TSRSIHIIQKGASEGVVELKHLL----------
>tr|N9S022|N9S022_9GAMM Uncharacterized protein OS=Acinetobacter ursingii NIPH 706 GN=F943_02577 PE=4 SV=1
---------------------------------------MKKLMVFSGAGMSAESGISTFRDSNGLWENYRIEDVATPEAWQRHPEIVQRFYNERRKTII
--YAEPNIAHQYIAQLEQYYD--VEVITQNIDDLHERAGSSQVLHLHGNIRLAKSSG-QDFYGWQLDLE-RHQCPE---DYPLRPHVVWFGEAVPAYDEA
IQLLQDADIFIVIGSTLTVYPVAGLIHEIPT-HCDAFYIDPQADYSRPSQYHLIKKTASEGMKQLFEQL----------
>tr|Q3V7G9|Q3V7G9_ACIAD NAD-dependent deacetylase (Regulatory protein sirtuin family) OS=Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) GN=npd
---------------------------------------MKKLVVFSGAGMSAESGIHTFRDHDGLWENYRIEEVATPEAWQQNPSLVQHFYNERRKNIL
--AAQPNLAHQIIAQLESCYQ--VQVITQNIDDLHERAGSTHVLHLHGNIRLAKSSG-QTFYGWQLDLN-QDKCNE---GYPLRPHVVWFGEAVPAYDDA
IAMLKDADVFIVIGSTLSVYPVAGLIHEIPN-HCEAYYIDPQADYFRPHQYTLLKMTATEGMKQLYLKL----------
>tr|A0A069D0P3|A0A069D0P3_9BACE NAD-dependent protein deacetylase of SIR2 family OS=Bacteroides graminisolvens DSM 19988 = JCM 15093 GN=JCM15093_1131 PE=3 SV=1
---------------------------------------MKKLVVLSGAGMSAESGLSTFRDAGGLWDKYPVEQVATPEGYRENPALVTQFYNERRKQLL
--TVAPNRGHELLAEMEKEFD--VTIVTQNVDNLHERAGSNRIIHLHGELTKVCSSYARYVKPDEYEVKLGDLAGD---GSQLRPFIVWFGEAVPQIETA
VTFVEQADVFVIIGTSMNVYPAAGLLNYVPK-QAAVYLIDPHEVQ-VYRHIEVIRKGASEGVVELLSRL----------
>tr|F3ZR83|F3ZR83_9BACE NAD-dependent deacetylase OS=Bacteroides coprosuis DSM 18011 GN=Bcop_0458 PE=3 SV=1
--------------------------------------MKKKVVVLTGAGMSAESGIATFRGAGGLWGKYPVQQVASIEGYHQDPELVQNFYNERRRELM
--DVKPNKGHELLAKMEEDYD--MTIITQNVDNLHERAGSNRIIHLHGELIKGCSSRNRFIVPGE-EIKMGDLAGD---GSQLRPFIVWFGEAVPEIETA
LPYVREADYFVIIGTSMNVYPAAGLLHYVSY-GTPIYVIDPNSVNVSTKGMTHIHKGASQGVAELIELL----------
>tr|I9P5H8|I9P5H8_HELPX NAD-dependent deacetylase OS=Helicobacter pylori CPY3281 GN=cobB PE=3 SV=1
---------------------------------------MKNLVILSGAGISAESGIKTFRDADGLWEGHDIMEVASPYGWKKNPQKVLDFYNQRRRQLF
--EVYPNKAHKALAELEKHYQ--VNIITQNVDDLHERAGSSRILHLHGELLSVRSEKDNLVYRWEKDLNLGDLAKD---KSQLRPDIVWFGEAVPLLEEA
ISLVKQAHLLIIIGTSLQVYPAASLYTHAHK-DAFIYYIDLRPKTPIPRMSNALMKAR------CMPCK----------
>tr|A0A0Q4B7U3|A0A0Q4B7U3_9BACE NAD-dependent deacetylase OS=Candidatus Bacteroides periocalifornicus GN=AL399_06290 PE=4 SV=1
-------------------------------------MARKKLVILTGAGISAESGIKTFRDSDGLWEEYRIEDVATPEAWERNPELVQEFYNERRRQLY
--KAEPNAGHRAIAEAERWID--VEVITQNVDNLHERAGSTHVLHLHGLLTQARSSRNDLIY--GTELKMGELAED---GTQLRPHIVWFGEAVPNLEPA
AALTRKADYFAVVGSSLNVYPAAGLIAYTRE-DIPLFLVDPKPVSAPRRHIEYIQEPASTGVPKLLERI----------
>tr|A0A0C3RD42|A0A0C3RD42_9PORP NAD-dependent deacetylase OS=Sanguibacteroides justesenii GN=BA92_14725 PE=3 SV=1
---------------------------------------MKKLVVLTGAGMSAESGIRTFRDSDGLWEEYNVMDVCTPEAWERDPELVNRFYNERRKQLY
--EAKPNAGHYGLAELETEYD--VQIITQNIDDLHERAGSSKVLHLHGELKKVRSSKT-LIY--GWELKLGTKGED---GSVLRPHIVWFGEAVPNIEPA
IELVSRADILVVIGTSLAVYPAASLLHYAPA-GCRILLIDPKIPESVNSRIEFIETGASEGVRILKEKL----------
>tr|R5UNW9|R5UNW9_9PORP Uncharacterized protein OS=Odoribacter laneus CAG:561 GN=BN709_02051 PE=3 SV=1
----------------------------------------MKLVILTGAGMSAESGIKTFRDSDGLWENYRIEEVCTPEALERNPELVNHFYNERRKQLY
--AAQPNKGHTGLAELEKYFD--LQIITQNIDDLHERAGSSRVLHLHGELKKVRSSKNDLIY--SWELKPGSRCED---GSLLRPHVVFFGEAVPNIEPA
IQLVKQADIFVVIGTSLAVYPAASLLNYAPE-NIPIFVIDPKIPQQAHYGFHLIEKGASEGVAELQKIL----------
>tr|A0A0L8V475|A0A0L8V475_9BACT Uncharacterized protein OS=Sunxiuqinia dokdonensis GN=NC99_39600 PE=3 SV=1
--------------------------------------MKKKLVVLTGAGISQESGIRTFRDMGGLWEEYDITEVATPEAWERNPELVMKFYNDRRKQLY
--ECEPNAGHLGLAELENDFD--VQIITQNVDDLHERAGSSKVLHLHGELKKVRSTKYELVY--GWELKFGDRCEK---GYQLRPHIVWFGEMVPAMEEA
VPLVEQADIFVVVGTSLNVYPAAGLLHYTRD-DVPLFVVDPERPPVYRK-VTFIEEKAGRGVAILKEKL----------
>tr|F9Z7H7|F9Z7H7_ODOSD NAD-dependent deacetylase OS=Odoribacter splanchnicus (strain ATCC 29572 / DSM 20712 / JCM 15291 / NCTC 10825 / 1651/6) GN=Odos
----------------------------------------MKLVILTGAGMSAESGIKTFRDSDGLWENYRIEDVCTPEALERNPELVNHFYNERRKQLY
--EAQPNAGHKGLAELENYFD--VRIITQNIDDLHERAGSKHVLHLHGELKKVRSSKNDSIY--GWELKPGTRCED---GSLLRPHVVFFGEAVPNIEPA
TDLVRQADIFVIIGTSLAVYPAASLLHYAPE-GIPVFVIDPKIPQQARMGYHLIEKGASEGVQELKNIL----------
>tr|A0A0P7C5E9|A0A0P7C5E9_9BACT NAD-dependent deacetylase OS=Leadbetterella sp. JN14-9 GN=AFM12_05495 PE=4 SV=1
--------------------------------------MRKHLVVLTGAGISAESGLKTFRDSDGLWENHRVEDVATPEAWHRDPHLVQRFYNMRRKAAA
--EAFPNEAHKTLAELESHFS--ISVITQNVDDLHERGGSSKVLHLHGELNKVRSVKNSLIY--DRQIEMGDLAED---GGQLRPHIVWFGEAVPMIEPA
VEICRSADIFMVVGTSLQVYPAAGLIDYTPY-DIPVFVIDKKRPQANPSNIHFHQGAAGEVLPELKETL----------
>tr|B3CAH8|B3CAH8_9BACE Transcriptional regulator, Sir2 family OS=Bacteroides intestinalis DSM 17393 GN=BACINT_01493 PE=3 SV=1
------------------------------------MAMKKNLVILSGAGMSAESGISTFRDAGGLWDKYPVMQVASAEGYVRDPELVIDFYNERRKQLL
--DVEPNAGHTGLAELEKDFN--VTVVTQNVDNLHERAGSTHVIHLHGELTKVCSSRDRYVRPEEYEVKMGDKAGD---GSQLRPFIVWFGEAVPEIETA
IGYVEKADIFVIIGTSMNVYPAAGLLNYVPR-TAEVYLIDPKPVD-TMRQIHVIQKGASEGVKELKTEI----------
>tr|A0A0M9UG72|A0A0M9UG72_9BACT NAD-dependent protein deacetylase of SIR2 family OS=Candidatus Symbiothrix dinenymphae GN=SAMD00024442_93_4 PE=4 SV=1
-------------------------------------MNKKHIVFLTGAGMSAESGIATFRDSGGLWEGFDPNKVASIEGWYADRAMMQDFYNARRAQLV
--DVEPNAGHKVIAELEADCD--VTVITQNVDNLHERAGSTNVIHLHGELTKACNEA-TDVL--TRAILKDERAAD---GSFLRPFIVWFGEQVPEIARA
AEIVATADTVVIVGTSMQVYPAAGLINYATR-DASLFLIDPSEVAVS-TRVTVIKAKASEGLKQLRDAL----------
>tr|R5KD44|R5KD44_9BACT NAD-dependent deacetylase OS=Prevotella sp. CAG:1124 GN=BN467_01437 PE=4 SV=1
---------------------------------------MKKLFVLTGAGMSVESGLSTFRDADGLWENYPVARVATHEAWLQDPVYVNNFYNMLRKKLL
--AAKPNEGHRLVAALEQQYD--VTVVTQNVDNLHEMAGSSRVIHLHGELMKTCSSRDRYWRADDIDVAPGEKAGD---GSLLRPYIVFFGEAVPNISVA
ADYAQQADLFVIIGTSLNVYPAAGLVQYAKP-SVPIYLIDPKPVMAARHDVRHIMKGASEGMKELTDIL----------
>tr|A0A0D0HAV0|A0A0D0HAV0_9BACT Contig80, whole genome shotgun sequence OS=Prevotella sp. P5-119 GN=ST44_11080 PE=4 SV=1
---------------------------------------MKKIVVLTGAGISAESGLSTFRDEDGLWEQHPVERVATHEAWERDPVYVNDFYNMLRGKLL
--AAKPNDGHRLVADLEKKYQ--VTVVTQNVDNLHEMAGSTHVIHLHGELMKVCSSRDHFIKPDNLEVAPGEKAGD---GSLLRPYIVFFGEAVPNIEKA
AAEVMEADIMIIIGTSLAVYPAAGLMRFAKP-GTPIYLIDPRPTVSAKQNLHVIAKGASEGMRELSAML----------
>tr|R5LR06|R5LR06_9BACT NAD-dependent deacetylase OS=Prevotella sp. CAG:1185 GN=BN473_02116 PE=4 SV=1
---------------------------------------MKKIVVLTGAGMSAESGLSTFRDADGLWENYPVSRVATHEAWESDPVYVNNFYNMLRKKLL
--AAKPNEGHRLVAALESKYK--VTVVTQNVDNLHEAAGSSDVIHLHGELMKVCSSRDHFIRPDCLDVKPGEKAGD---GSLLRPYIVFFGEAVPNIEKA
AQEAMSADIFVIIGTSLNVYPAAGLVQYVKP-GVPVYLIDPKPVMAARHDVRQITAGASEGMRRLSEIL----------
>tr|A0A0D0IQV4|A0A0D0IQV4_9BACT Contig91, whole genome shotgun sequence OS=Prevotella sp. P5-119 GN=ST44_12875 PE=3 SV=1
---------------------------------------MKKIVVLTGAGMSAESGLSTFRDADGLWENYPVARVATHEAWETDPDYVNDFYNMLRGKLL
--EAKPNRGHELVAALQEKYD--VSVVTQNVDNLHEQAGSRKVIHLHGELMKVCSSRDHFIKPGNLTVAHGEKAGD---GSLLRPFIVFFGESVPMIEPA
VEEVEKADMMIIIGTSLVVYPAAGLVRYVRP-GAPIYLIDPKPSVSGRSDIRQIVKGASAGMEELMQIL----------
>tr|A0A0A2DWC9|A0A0A2DWC9_9PORP Uncharacterized protein OS=Porphyromonas sp. COT-108 OH1349 GN=JT26_06400 PE=4 SV=1
-------------------------------------MKKKKIVFLTGAGMSVESGLETFRDADGLWAKYRIEDVCTPEALRRNPDLVREFYNMRREEIA
--KVKPNGGHLAIAALEEEYD--VVVVTQNIDDLHERAGSTQIVHLHGEAMKCASLSDLPLP--RLALTAEDVDAR---GLPLRPFVVFFGESVPMLDEG
IRHVSEADIFVIVGTSLNVYPAAGLIHYAKP-DTPIFLIDPKEVAMS-LEFTHFRCGSSEGMQLLTAKL----------
>tr|A0A0A2EVJ7|A0A0A2EVJ7_PORCN Uncharacterized protein OS=Porphyromonas cangingivalis GN=HQ35_01480 PE=4 SV=1
------------------------------------MDRKPILTVLTGAGMSAESGLATFRDSDGLWAKYKIEEVCTPEALRANPALVIDFYNMRRRECA
--KAQPNEAHRLLAELEKDYD--VRIVTQNVDDLHERAGSTNVIHLHGELFKCASMANLPLP--RIEMTVEDKDAD---GYMLRPFIVFFGEQVPRLEDG
AREVQRADIFLIIGTSLNVYPASGLIHYTKS-DTPIFLIDPNDVHA--SKVHYIKAGASEGMKKFVEIL----------
>tr|U5Q6A2|U5Q6A2_9BACT NAD-dependent deacetylase OS=Bacteroidales bacterium CF GN=cobB PE=3 SV=1
-------------------------------------MNKAHIVVLSGAGISADSGLETFRDADGLWAKHRVEDVCTPEALIRNPELVLDFYNKRRHQLK
--SAEPNEGHKALARLEEFYD--VDVITQNVDDLHERAGSSRVLHLHGELMKCRSMKDSYIAD---DLHVGDLAPD---GGQLRPHIVFFGEPVPMFEKA
SEIASKADILIVVGTSLEVYPAASLIYNIPD-NVPVYLVDPSPLRVKLKGVRYICKRAAIGLPRLYDEL----------
>tr|B5D3U9|B5D3U9_BACPM Transcriptional regulator, Sir2 family OS=Bacteroides plebeius (strain DSM 17135 / JCM 12973 / M2) GN=BACPLE_03703 PE=3 SV=1
---------------------------------------MKNLVVLTGAGMSAESGISTFRDAGGLWDQYPVEQVATPEGYAANPKLVINFYNERRKQLL
--EVKPNRGHELLAELEKYFH--VTVITQNVDNLHERAGSTEVIHLHGELTKVTSSFQRFIKPEEYEVRMGDKAPD---GSQFRPFIVWFGEAVPMIETA
IDYVDKADIFVIIGTSLNVYPAAGLLNYVHP-GVPVYLIDPKEVR-IGRAVRVIQKGASEGMEELKKML----------
>tr|F8WXT0|F8WXT0_9PORP NAD-dependent deacetylase OS=Dysgonomonas mossii DSM 22836 GN=HMPREF9456_00860 PE=3 SV=1
---------------------------------------MRHIVVLTGAGMSAESGIATFRDSGGLWEQYSIEDVATPEGFSRNPQLVLDFYNARRKAAF
--EAKPNKGHVGLVEMEKEYK--VSIITQNVDELHERAGSTNVLHLHGELSKVRSTVD-LIYPDNCEIHLGDKCEK---GSQLRPHIVWFGEAVPMIEKA
MKIVQTADIFVVIGTSMNVYPAAGLLNYVHA-GVPVYLIDPKEVNVHP-GIHFIKKGASEGVAELRDIL----------
>tr|R8Y309|R8Y309_ACICA Uncharacterized protein OS=Acinetobacter calcoaceticus ANC 3811 GN=F935_01474 PE=4 SV=1
---------------------------------------MINLVVFSGAGMSAESGISTFRDSNGLWENYDIQQVATPEAWQKSPALVQRFYNKRRKNIL
--EAKPNEAHQYIAKLQDYFD--VHVITQNIDDLHERAGNSNVLHLHGNIRLAKSSG-TRFYGWKLDLE-NDLCPD---GYPLRPHVVWFGEAVPAYEEA
IRLVQSADVFIVIGSTLSVYPVAGLVHEISD-QCKAYYIDPKADYGRPQQYELLKMSATQGMHQLFENL----------
>tr|R7CWM6|R7CWM6_9BACE NAD-dependent deacetylase OS=Bacteroides sp. CAG:462 GN=BN666_02066 PE=4 SV=1
-------------------------------------MKKQKIVLLTGAGMSAESGIKTFRDSDGLWENYPVQQVASIEGYEADPGLVLDFYNARRAELL
--RTEPNHGHRMVAALEQHFD--VTVVTQNVDNLHERAGSSHVIHLHGELMKATSSRNSCICPARPVIRLGDKAAD---GSQLRPFIVWFGEAVPRFEDA
IAEAETADIFVIIGTSMQVYPAAGLVRYIRP-GVPVYVIDPKAVAVHASPVHTITKGASDGMDELFKML----------
>tr|A0A0A8XE21|A0A0A8XE21_ACICA NAD-dependent deacetylase, regulatory protein sirtuin family OS=Acinetobacter calcoaceticus GN=P23_1409 PE=4 SV=1
------------------------------------MTYMTKLVVFSGAGMSAESGISTFRDSNGLWENYNIQQVATPEAWQKNPALVQRFYNERRKNIL
--ESQPNQAHQYISKLQDYFE--VQVITQNIDDLHERAGSSNVLHLHGNIRLAKSSG-TQFYGWKLDLE-HDLCPD---GYALRPHVVWFGEAVPAYEEA
IRVVQSADIFIVIGSTLSVYPVAGLVHEIAA-QCKAYYIDPKADHVRPQQYELLKMSATQGMHELFKNL----------
>tr|R5RPK3|R5RPK3_9BACE Silent information regulator protein Sir2 OS=Bacteroides sp. CAG:545 GN=BN702_01403 PE=3 SV=1
--------------------------------------MKQKLVVLTGAGVSAESGISTFRDNGGLWDNYDPQQVASIEGWYKNPGLMLDFYNIRRHELE
--GVRPNDAHRAIASLQDSFN--VNVITQNVDNLHERAGSSNVLHLHGELTKVRPENDKTVF--YSEVHLGDKAPN---GHQLRPHIVWFGEPVPKIERA
IDIVSDADILLIVGTSLSVYPAAGLYRYASL-DTPIYLIDPGQVNVR-SRIQHIMAKATDGMKIFQEKI----------
>tr|R5I603|R5I603_9BACT Transcriptional regulator OS=Alistipes sp. CAG:831 GN=BN796_00123 PE=3 SV=1
---------------------------------------MKKLAVLSGAGVSKESGINTFRDSDGMWEQYPVEEVASIEGWYRNPGLVLDFYNARRRDIR
--TRQPNEAHRIIAALEKDFD--VTVITQNIDNLHERAGSSKVIHLHGEITKARGEK-KPVY--YSDIHLGDLDDR---GEQLRPDIVWFGEAVPMIEPA
AEIVSECDILLVIGTSLVVYPAAGLVNYVRH-GVPLYLVDPKPIHVG-KYYTQIQDVATAGMRRFLDLV----------
>tr|R5AXP6|R5AXP6_9BACE NAD-dependent deacetylase OS=Bacteroides sp. CAG:927 GN=BN813_00112 PE=4 SV=1
------------------------------------MNSKPKLVISTGAGMSAESGLSTFRDSGGLWDNYNVMDVASADGFARNPELVHKFYNIRRRELM
--NVEPNEGHRGLVELEKWYD--TYVITQNVDNLHERAGSSNVVHLHGELMKIRSLTHERVYPDNLETTVDTVDKY---GDHVRPHIVFFQEAVPMFERA
VELAEEADVFVVIGTSLVVYPAAALLHYVRR-GIPVYYIDPNPAPVP-DGVTVLKMGASEGVRKLVEIL----------
>tr|R6E5C4|R6E5C4_9BACE Silent information regulator protein Sir2 OS=Bacteroides sp. CAG:709 GN=BN760_00324 PE=3 SV=1
---------------------------------------MKKLVVLTGAGVSAESGISTFRDNGGLWDNYDPQQVASIEGWYQNPGLMLDFYNIRRRELE
--GVRPNDAHRAIASLQDNFN--VNVITQNVDNLHERAGSSNVLHLHGELTKVRPENDKTVF--YGEIHLGDKAPN---GHQLRPHIVWFGEPVPKIEKA
IDIVSETDLLLIVGTSLSVYPAAGLYRYAPL-DAPVYLIDPGEINVR-RRVRHIQTKATEGMKIFMSDV----------
>tr|N9DQ13|N9DQ13_9GAMM Uncharacterized protein OS=Acinetobacter bouvetii DSM 14964 = CIP 107468 GN=F941_01556 PE=4 SV=1
-------------------------------------MTMQKIVVFSGAGMSAESGINTFRDSDGLWEQHRIEDVATPEAWTRDPELVQRFYNERRKHIL
--AAVPNEAHHLIAELDDFFN--VQVITQNIDDLHERAGSQNVLHLHGNIRFAKSSG-QELFGSDLNLD-TDKCPD---GYPLRPHVIWFGEAVPAYEDA
SVSVQTADIFIVIGTSLAVYPVAGLIHEIPA-NCRAFYIDPKADYQRPEQYQLIKAGASEGMKMLFQQL----------
>tr|A0A0Q1BYY6|A0A0Q1BYY6_9GAMM NAD-dependent deacylase OS=Acinetobacter soli GN=APD01_05220 PE=4 SV=1
---------------------------------------MKKLVVFSGAGMSAESGIHTFRDSDGLWENYKIEDVATPEAWQKDPELVQRFYNERRKNIL
--NATPNSAHLAIATLEHQFD--VNVITQNIDDLHERAGSSRVLHLHGNIRFAKTSG-QELYGSELKLD-RDYCKD---GYPLRPHVVWFGESVPAYQDA
IHQIRQADIFIVIGSTLSVYPVAGLIHEISG-LCEAYYIDPKADYHRPKQYQLLKMTASEGVKTLSETL----------
>tr|B6YR36|B6YR36_AZOPC NAD-dependent deacetylase OS=Azobacteroides pseudotrichonymphae genomovar. CFP2 GN=CFPG_395 PE=4 SV=1
-------------------------------------MNRKRIAIFSGAGMSAESGISTFRDSNGLWDNYNVMQVAHIDSWCVNQSLMLQFYNERRQHLA
--SVSPNKGHRIIAEWEKDFD--VTVITQNIDNLHERAGSSHVIHLHGELTKACSSK-KHII--YNDILPGDLSVD---GSQLRPFIVWFGEDVPEMGNA
TLAVSNANVIIIVGTSMQVYPAANLIHFAKA-NTAIYLIDPAEIPILSANVEVIQEKASKGLALLKERF----------
>tr|W4UQZ4|W4UQZ4_9BACE NAD-dependent protein deacetylase OS=Bacteroides reticulotermitis JCM 10512 GN=JCM10512_1495 PE=3 SV=1
---------------------------------------MKKLVVLSGAGMSAESGINTFRDTGGLWEQYSVEEVATPEGYRRDPELVTRFYNERRKQLL
--QVEPNRGHELLAELEKEFD--VTVVTQNVDNLHERAGSSRVIHLHGELTKVCSSRDHYIKPDEFDINIGDLAGD---GTQLRPFIVWFGEAVPMIETA
VRYVEQADLFVIIGTSMNVYPAAGLLNYVGY-GVPVYLIDPNPVD-VSRKIHVIRKGASAGMAELIKTL----------
>tr|A0A015TB35|A0A015TB35_BACFG Sir2 family protein OS=Bacteroides fragilis str. 3986 T(B)9 GN=M083_4402 PE=3 SV=1
---------------------------------------MKNLVVLSGAGMSAESGISTFRDAGGLWDRYPVEQVATPEGYARDPELVTHFYNERRKQLL
--EVEPNRGHELLAELEKDFQ--VTIVTQNIDNLHERAGSSHIIHLHGELTKVCSSRDHYIKPEEFEVKIGDLAGD---GSQLRPFIVWFGESVPEIETA
IDWVEKADVFVIIGTSMNVYPAAGLLNYVPR-NAEIYLIDPKPVD-VSRPIHVIQKGASEGVAELREKL----------
>tr|A0A0P7YVT9|A0A0P7YVT9_9BACT NAD-dependent protein deacetylase NpdA OS=Algoriphagus marincola HL-49 GN=npdA PE=4 SV=1
---------------------------------------MKRLVVLTGAGISAESGIKTFRDSGGLWEGHDVMEVASPEGWRRNQNLVQEFYNLRRKQMY
--ECQPNLAHRILVELEEHFE--VHIITQNVDDLHERAGSSKVLHLHGELKKAQSSLDKLVY--HWEIKKGDKCAK---GSQLRPHVVWFGEPVPKMLEA
IELAQEADIFLIVGTSLEVYPAASLVSYVPD-HAEIYVVDPNIPSSKHHRAKHLVQPATKGVENLKKIL----------
>tr|A0A0M0TGY2|A0A0M0TGY2_9FLAO NAD-dependent deacetylase OS=Flavobacterium sp. VMW GN=AKO67_20205 PE=3 SV=1
--------------------------------------MKKKLVVLTGAGISAESGIKTFRDSDGLWEGHDVMEVATPEGWNKNQELVLDFYNKRRQQLK
--EVQPNLGHQILAELEKDFD--VYIITQNVDDLHERAGSTKVLHLHGELLKVRSVKNNLILDWTADLLTGDLDEN---GHQLRPHIVWFGEEVPALEEA
IDITETADYFAVIGTSLQVYPAAGLISYTPS-TTPVFYIDPKPISIPRNKVEVIAKTATEGVAELREKL----------
>tr|A0A0D0EWD1|A0A0D0EWD1_9FLAO NAD-dependent deacetylase OS=Flavobacterium hibernum GN=IW18_07915 PE=3 SV=1
--------------------------------------MKKKLVVLTGAGISAESGIKTFRDSDGLWEGHDVMEVATPEGWRKNQELVLDFYNKRRAQLK
--EVKPNLGHQILAELEQDFD--VHIITQNVDDLHERAGSTKVLHLHGELLKVRSTQNDLILDWNDDLYTGDLDKN---GHQLRPHIVWFGEDVPALEEA
ISIVEKADYFAVIGTSLQVYPAAGLISYTYS-ITPVFYIDPKPIAIPQNKVEVIAKIASEGVSDLRDRL----------
>tr|F4B0V9|F4B0V9_DOKS4 Silent information regulator protein Sir2 OS=Dokdonia sp. (strain 4H-3-7-5) GN=Krodi_2586 PE=3 SV=1
-------------------------------------MSKQNIVVLSGAGISAESGLKTFRDADGLWEGHDVMEVATPEGWRNNQELVLRFYNDRRRQLL
--EVTPNAAHKDLVQLEEDYN--VTIITQNVDDLHERAGSSDVIHLHGELLKVRSSKDSD--PWTTDLKKGDLCAL---GSQLRPHIVWFSEEVPLLEKA
AELVSKADFIIIVGTSMQVYPAAGLIDFAKP-NAQIYFIDPKPSIAQ-ERLTIVPEIASTGIKKVVETL----------
>tr|A0A095U0W5|A0A095U0W5_9FLAO NAD-dependent deacetylase OS=Flavobacterium aquatile LMG 4008 GN=LG45_08245 PE=3 SV=1
---------------------------------------MKKLVVLTGAGISAESGIKTFRDSDGLWEGHNVMDVATPEGWRKNQELVLDFYNQRRKQLH
--EVQPNLGHKILAELENDFD--VHIITQNVDNLHERAGSSKVLHLHGELFKVRSIIDNNILDWKIDLKTGDLDAN---GFQLRPHIVWFGEDVPALEEA
LVITQQADYFAVIGTSLQVYPAAGLVEFTLP-NVPIYYIDPNPATIKSNPVEIIPMNATEGVQFLREIL----------
>tr|A0A0A2GRA0|A0A0A2GRA0_9FLAO NAD-dependent deacetylase OS=Dokdonia donghaensis DSW-1 GN=NV36_02525 PE=3 SV=1
---------------------------------------MQKVVVLSGAGMSAESGLKTFRDANGLWEGHDVMQVATPEGWKANQELVLKFYNERRKQLL
--EVLPNQGHLDLVKLEEAYD--VHIITQNVDDLHERAGSSKVIHLHGELLKVRSCNDSQ--EWKKDLKTGDLCPQ---GGQLRPHIVWFGEEVPLMEEA
SVLVSEADYIIIVGTSMQVYPAAGLITLAQP-NAEIFFIDPAPSITQ-KGLTILPERATTGVKKVVDTL----------
>tr|A0A0Q5UW29|A0A0Q5UW29_9FLAO NAD-dependent deacylase OS=Flavobacterium sp. Leaf359 GN=ASG38_09425 PE=4 SV=1
--------------------------------------MKKKLVVLTGAGISAESGIKTFRDSDGLWEGHDIMEVASPEGWKKNPVLVLDFYNKRRQQLK
--EVLPNAAHIILAELEQHFD--VHIITQNVDDLHERAGSTKVLHLHGELLKARSTQNRHIIEWQDDLFLGNLDAS---GHQLRPHIVWFGEAVPALDEA
VRITHEADFFAVVGTSLQVYPAAGLVDFAKP-GTPLYYVDLNPARITSNELEIIPKTASEGMKILKEKL----------
>tr|I5C391|I5C391_9BACT Silent information regulator protein Sir2 OS=Nitritalea halalkaliphila LW7 GN=A3SI_10794 PE=3 SV=1
--------------------------------------MKKKLVVFTGAGISAESGLKTFRDSDGLWEGHDVMQVATPEGWAANPELVLTFYNQRRQQAQ
--EVLPNVAHQLLVELEADFD--VHIITQNVDDLHERAGSSHVLHLHGELDKVQSTLNDYIV--GAPISLGDCCPQ---GGQLRPYVVWFGEPVPAYADA
LAITREADIFLVIGTSLQVYPAAGLLYETPS-GIPVFIVDRQIPDVRPKNCIPLEGSACAMAPILKTQL----------
>tr|A0A066WU73|A0A066WU73_9FLAO NAD-dependent deacetylase OS=Flavobacterium sp. EM1321 GN=FEM21_22370 PE=3 SV=1
--------------------------------------MKKKLVVLTGAGISAESGLKTFRDSDGLWEGHNVMDVASPEGWRKNPELVLDFYNQRRRQLK
--EVKPNLGHRELAQLQIHFD--VHIITQNVDDLHERAGSKKVLHLHGELLKVRSTKNKFILEWEGDLNLGDVDSQ---KNQLRPHIVWFGESVPAFDEA
ITITETADYFAVIGTSLQVYPAAGLIAFVPQ-NIPVFYIDPNPIQIPRNPLETIPLNASEGVPYLKNSL----------
>tr|A0A0Q1BMQ7|A0A0Q1BMQ7_9FLAO NAD-dependent protein deacetylase of SIR2 family OS=Flavobacterium daejeonense GN=RCH33_1467 PE=4 SV=1
--------------------------------------MKKKLVVLTGAGMSAESGLKTFRDSNGLWEGHDVMEVASPEGWQKNPELVLEFYNQRRRQLK
--EVQPNLGHQELAQLQIHFD--VHIITQNVDDLHERAGSKKVLHLHGELLKVRSTKNKYILDWEGDLNLGDVDSF---KNQLRPHIVWFGESVPAFDEA
LNITETADYFAVIGTSLQVYPAAGLLAFVPP-TTPVFYIDPNPISIPRNPLETIPMTATKGVPVLKNHL----------
>tr|A0A0C1E0B1|A0A0C1E0B1_9FLAO NAD-dependent deacetylase OS=Flavobacterium sp. KMS GN=OA93_01180 PE=3 SV=1
--------------------------------------MKKKLVVLTGAGISAESGIKTFRDSDGLWEGHDVMEVATPEGWYKNPELVLDFYNQRRKQLK
--EVTPNLGHQILAELEKDFD--VHIITQNVDDLHERAGSTKVLHLHGELLKVRSSQNNYILDWNDDLFMTHLDDK---GNQLRPHIVWFGEEVPALEEA
IDIAEQADYFAVIGTSLQVYPAAGLISYTPA-NAPLFYIDPKPIKIPRNKIEVIPEVASKGMEILKTKL----------
>tr|R6U4M4|R6U4M4_9BACE Silent information regulator protein Sir2 OS=Bacteroides sp. CAG:770 GN=BN777_00821 PE=3 SV=1
---------------------------------------MKKLVVLTGAGVSAESGISTFRDNGGLWDNFDPNEVASIEGWHKNPALMLDFYNIRRRELA
--NVKPNAAHLAIADLQNKYD--VNVITQNVDNLHERAGSSKVLHLHGELTKVRPENDASVF--YGEIHLGDLAPN---GHQLRPHIVWFGEPVPKIERA
IDLVSEADILLIVGTSMSVYPAAGLYRYAPA-STPIYLIDPSNVNVR-KRIVHIHAKATDGMEVFKENI----------
>tr|R5BII5|R5BII5_9BACE NAD-dependent deacetylase OS=Bacteroides sp. CAG:1060 GN=BN459_00714 PE=4 SV=1
-------------------------------------MSKKSIAVLTGAGVSAESGLKTYRDNGGLWNDYDPMKVASVEGWNADPGLVLEFYNQRRAELG
--HTAPNEAHRLIAELENSYK--VNVITQNVDNLHERAGSTNVLHLHGELTKIRPENDEYVV--YGRVVLGDMAPN---GAQYRPHIVFFGEAVPKMNRA
IDIVSAADAIIIVGTSLSVYPAASLYRYASF-ETPVYLIDPAEMKFR-PRITHIRKIASEGMKDCLDLL----------
>tr|R5BEE9|R5BEE9_9BACT NAD-dependent deacetylase OS=Alistipes sp. CAG:514 GN=BN689_00679 PE=3 SV=1
-----------------------------------MNSAKKKIAVLTGAGVSAESGLSTFRGNNGLWGEYDPEEVASIQGWYRNRELVLNFYNGLRKRLS
--EVKPNAAHYAIADLEKEYS--VTVITQNVDNLHERAGSTKVLHLHGEATKVRPEDRKEVI--YDEVHLGDKAPN---GSQLRPHIVFFGEAVPNIEKA
IDIVSAADIMLIVGTSLNVYPAAGLYRYAPN-GIPIYLIDPEDVAIA-PRITQIRQVATKGMETFRRML----------
>tr|A0A0A2E7F6|A0A0A2E7F6_9PORP NAD-dependent protein deacylase OS=Porphyromonas macacae GN=HQ47_10515 PE=3 SV=1
----------------------------------AMDTGRKKIVALTGAGMSAESGISTFRDSNGLWEQYRVEDVASIEGWIRNPKLVLDFYNARRASYK
--GCEPNEGHRLLAGLEKEYE--VVVVTQNVDDLHERAGSTNIIHLHGELMKNCSDGHETVFPDNPELHLGDLAPD---GTQLRPYIVWFGEAVPKITDA
AREIETADIVLVIGTSLNVYPAAGLLAYAPS-SAPVYLIDPKPVSSSRSDIHKITAGASEGMRLFCEEL----------
>tr|A0A031LXI6|A0A031LXI6_9GAMM NAD-dependent deacetylase OS=Acinetobacter sp. Ver3 GN=CL42_00500 PE=4 SV=1
-----------------------------------MNQSKTKLVIFSGAGMSAESGINTFRDSDGLWENHRIEDVATPEAWRNNPVLVQRFYNERRKKIL
--ASEPNAAHLAIAALEQHYD--VHVITQNIDDLHERAGSKKVLHLHGNIRLAKTSG-DKFYGTELDIS-RDFCDA---GYPLRPHVVWFGESVPAFEEA
EVICQQAEIFVVIGTSLAVYPVASLVHSISP-SCDAYYIDPKADLGRPQHYTCISKSATEGMQDLAKLL----------
>tr|F2IIB0|F2IIB0_FLUTR NAD-dependent deacetylase OS=Fluviicola taffensis (strain DSM 16823 / RW262 / RW262) GN=Fluta_1832 PE=4 SV=1
--------------------------------------MKCNLVILSGAGISAESGIKTFRDADGLWENHSIEEVATPEAWKNNPTLLQRFYNERRLKVI
--SSNPNLAHHYFKELQEHFH--VQIITQNIDDLHERAGNSNVLHLHGNIRYAKSSG-SKYY--GHELKMTDFCDD---GFPLRPHVVWFGEEVPLLSDA
AEIIKQADIFIVIGTSLQVYPAARLIHNAPK-KARKIVVDPAAKKLNSTDYIILNCTAEESVSHLKQIL----------
>tr|I0KEE3|I0KEE3_9BACT Silent information regulator protein Sir2 OS=Fibrella aestuarina BUZ 2 GN=FAES_4497 PE=3 SV=1
------------------------------------MKTRKKIVVLSGAGISAESGIATFRDSNGLWENHRIEDVATPEAWRRNRELVLDFYNQRRKQAL
--TVEPNAGHQALVRLEEAYD--VTIITQNVDGLHEKAGSSHVLHLHGELSKARSSVDSLIY--GWEIKLGDTCEK---GSQLRPHIVWFGEAVPTMEEA
VDIAITADMFIVVGTSLVVYPAAGLVDFIPD-TVPIYVVDPNLPEVRRPNLTLIGEPASTGLTKLADQL----------
>tr|I2GI53|I2GI53_9BACT Silent information regulator protein Sir2 OS=Fibrisoma limi BUZ 3 GN=BN8_02685 PE=3 SV=1
------------------------------------METRKKIIVLSGAGISAESGIPTFRASDGLWENHRIEDVATPEAWYRNPVLVQDFYNQRRKQAL
--SVQPNAGHLALVKLEEYFD--VTVITQNVDNLHEKAGSSNVVHLHGELFKSRSTQDDLVY--GWEIRMGDCCEK---GSQLRPHIVWFGEAVPMMDVA
MDITEQADVFIVVGTSLAVYPAAGLIYSVRP-GIPIYIVDPNIPDVARKNMTMIPEPATVGLTRLADQL----------
>tr|D2QCS2|D2QCS2_SPILD Silent information regulator protein Sir2 OS=Spirosoma linguale (strain ATCC 33905 / DSM 74 / LMG 10896) GN=Slin_2032 PE=3 SV=1
------------------------------------MSTRKKIVVLSGAGISAESGIPTFRASDGLWENHRIEDVATPEAWHRNPALVQDFYNQRRKQAL
--SVQPNAGHLALVKLEEKFD--VTVITQNVDNLHEKAGSSKVVHLHGELFKSRSTVDSLIY--GWELKDGDVCAK---GSQLRPHIVWFGEAVPMMDIA
LDITEQADLFIVVGTSLNVYPAAGLVYAVRE-GVPVYVVDPSIPDMHKNNVTFIAEPATIGLTQLAEQL----------
>tr|R6G661|R6G661_9BACE Transcriptional regulator Sir2 family OS=Bacteroides sp. CAG:633 GN=BN744_01108 PE=3 SV=1
---------------------------------------MKNLVVLSGAGMSAESGISTFRDAGGLWDRYPVEQVATPEGYARNPELVINFYNERRRQLL
--EVEPNEGHRGVVALEKDFN--VTVVTQNIDNLHERAGSTHIIHLHGELTKVCSSRDHFIKPSEYEVHLGDKAGD---GSQLRPFIVWFGEAVPEIETA
IEYVQQADIFVIIGTSLNVYPAAGLLHYVPR-EAEVYLIDPKPVD-TSRPVHVIRKGASEGVAELRKLL----------
>tr|E6SPI2|E6SPI2_BACT6 Silent information regulator protein Sir2 OS=Bacteroides helcogenes (strain ATCC 35417 / DSM 20613 / JCM 6297 / P 36-108) GN=Ba
---------------------------------------MKNLVVLSGAGMSAESGISTFRDAGGLWDRYPVEQVATPEGYARDPELVINFYNERRRQLL
--DVKPNAGHAGLAELERDFN--VTVVTQNVDNLHERAGSTHVIHLHGELTKVCSSRDHFIKPGEYEVKMGDKAGD---GTQLRPFIVWFGEAVPQIETA
IRYVEKADIFVIIGTSMNVYPAAGLLNYVPR-EADVYLIDPKPVD-ALRQIHVIRKGASDGVEELISLL----------
>tr|W4PGR4|W4PGR4_9BACE NAD-dependent protein deacetylase of SIR2 family OS=Bacteroides pyogenes DSM 20611 = JCM 6294 GN=JCM6294_1529 PE=3 SV=1
---------------------------------------MKNLVVLSGAGMSAESGISTFRDAGGLWDRYPVEQVATPEGYARDPALVTRFYNERRKQLL
--EVKPNRGHELVAELEKDFR--VTVVTQNVDNLHEKAGSSHVIHLHGELTKVCSSRDRYVKPEEYEVKIGDLAGD---GTQLRPFIVWFGEAVPEIETA
IRYVEKADVFVIIGTSLNVYPAAGLLHYVPH-EAEVYLIDPKPVD-TSRRVHVIAKGASEGMAELRSIL----------
>tr|R5SQ92|R5SQ92_9BACE NAD-dependent deacetylase OS=Bacteroides sp. CAG:661 GN=BN750_00777 PE=3 SV=1
--------------------------------------MMKNLVVLSGAGMSAESGISTFRDARGLWDRYPVEQVATPEGYARDSELVINFYNERRKQLL
--EVKPNEGHIGVAQLEKDFN--VTVITQNIDNLHERAGSTKVIHLHGELTKMCSSRDRYIKPEEYETRATDRAGD---GSPLRPFIVWFGEAVPEIETA
IGYVEQADIFVIIGTSMNVYPAAGLLHYVPA-RAEVYLIDPKPVD-TTRPIHVIRKGASEGVKELRALL----------
>tr|D0TKR7|D0TKR7_9BACE NAD-dependent deacetylase OS=Bacteroides sp. 2_1_22 GN=npdA PE=3 SV=1
----------------------------------EGGIVMKNLVVLTGAGMSAESGISTFRDAGGLWDRYPVEQVATPEGYQRDPALVINFYNERRKQLL
--EVKPNRGHELLAELEKSFH--VTVVTQNIDNLHERAGSSHIIHLHGELTKVCSSRDHYIKPEEYEVKMGDKAGD---GTQLRPFIVWFGEAVPEIETA
IQYVEKADIFVIIGTSLNVYPAAGLLHYVPR-GAEVYLIDPKPVD-TSRSIHVIQKGASEGVAELKQLL----------
>tr|D4IJ91|D4IJ91_9BACT NAD-dependent protein deacetylases, SIR2 family OS=Alistipes shahii WAL 8301 GN=AL1_03200 PE=4 SV=1
---------------------------------------MKKLVVFTGAGVSADSGLATFRDSDGTWGNYRIEEVCIPEALDFNRRGVIRFYNERRAEML
--KAEPNAAHRAIAGLERDFD--VRVITQNVDNLHERAGSTHILHLHGELTKLRSTDDSLILGV--EQGFDDRAPD---GSLLRPHIVFFGEPVPEFDRA
AELAAGADILMVVGTSLAVYPAASLVRCVRP-DIPVYVVDPGRPAIRRNPLEVIRKRAAEGVPELADRL----------
>tr|B0MXF5|B0MXF5_9BACT NAD-dependent deacetylase OS=Alistipes putredinis DSM 17216 GN=npdA PE=3 SV=1
---------------------------------------MKKIVVFTGAGVSADSGLATFRDSDGLWANYRIEDVCTPEALRDNRAQVVDFYNMRRREML
--GKEPNAGHRAIAGLEKCFD--VEVITQNVDNLHERAGSSRVTHLHGELTKLRSSRDELIVGW--EQRLDATAPD---GSLLRPHIVFFGEAVPMFERA
AEIAGTADLMVVVGTSLAVYPAASLVRYVRP-DVPIFLVDPGNPDTARNPLTHIRSRAAEGMPELAERL----------
>tr|E4MDT7|E4MDT7_9BACT NAD-dependent deacetylase OS=Alistipes sp. HGB5 GN=npdA PE=3 SV=1
---------------------------------------MKRIVVFTGAGVSADSGLATFRDSDGLWADYRIEDVCTPEALAHNRATVIEFYNKRRREML
--AAEPNAGHRAIAELERDFE--VEVLTQNVDNLHERAGSSRVTHLHGELIRLRSSRDGLIVGW--EQRLDATAPD---GSLLRPHIVFFGESVPMFERA
AEIAQTADIMVVVGTSLAVYPAASLVRYVRP-DIPIYVVDPGNPDTARNPLTLIRKRAAEGMPELAALL----------
>tr|R6VQZ8|R6VQZ8_9BACT NAD-dependent protein deacetylase SIR2 family OS=Alistipes sp. CAG:268 GN=BN576_01912 PE=3 SV=1
---------------------------------------MKRIVVFTGAGVSADSGLATFRDSDGLWANYRIEDVCTPEALARNRALVIEFYNKRRHEML
--AARPNAAHEAIARLEQGYD--VEVVTQNVDDLHERAGSTRVTHLHGELRKLRSSRNDLIVGW--EQPLDAMAPD---GSLLRPHIVFFGESVPMFERA
AEIAQTADAMLVVGTSLAVYPAASLVRYVRP-EIPIWVVDPGNPDTGRNPLTVIRKRAAEGVPELVDDL----------
>tr|R5W4U2|R5W4U2_9BACT Uncharacterized protein OS=Alistipes sp. CAG:157 GN=BN505_00128 PE=3 SV=1
-------------------------------------MEKKKLVVFTGAGVSADSGIATFRDADGLWANYRIEDVCTPEALARNREQVIGFYNMRRRELL
--ASKPNAGHYALAGLEDMFD--VRVITQNIDDLHERAGSRQVLHLHGELRKLRSTVDRLVFGW--EQKPDDRAPD---GSPARPFVVFFGEAVPNFERA
AEIAAQADLMIVAGTSLAVYPAASLVRYVPG-GVPVYLVDPGEPDVRRNLKEHIRMRGAEGLPLLAARL----------
>tr|G5HAI4|G5HAI4_9BACT Uncharacterized protein OS=Alistipes indistinctus YIT 12060 GN=HMPREF9450_01649 PE=3 SV=1
--------------------------------------MSKKIVVFTGAGMSADSGLSTFRDADGLWDRYRIEDVCTPEALAKNRQLVIDFYNIRRKELL
--SKEPNAGHLAIRRLEDYFE--VEVITQNIDDLHERAGSSRITHLHGELRKLRSSIDTLTVGW--KQEYDTRCKD---GSLLRPFVVFFGESVPMFDRA
AQIASTADIFVIVGTSLAVYPAASLVRYIRP-DVPVYLVDPNEPDMRRNPLEAIRMRAAEGMPLLTEKL----------
>tr|B3QYR0|B3QYR0_CHLT3 Silent information regulator protein Sir2 OS=Chloroherpeton thalassium (strain ATCC 35110 / GB-78) GN=Ctha_2684 PE=4 SV=1
--------------------------------------MKKRIVIFSGAGLSAESDIPTFRDSNGLWESHRIEDVASPEGWQRNPALVLDFYAKRYEKMQ
--TCKPNSAHEAIAKLSLRHE--VICITQNIDNLLEQAGVETVWHLHGRIDVQKCEWARFQCAIKRPIAFGDACPVC--GGQLRPDVVWFGEAVDMRQSY
QELVRTTDIFIGVGTSAQVYPAAGLLSIFEK-VRDKYFIDPKPAYSVLSDFEVLNGSASEKMPLLVDQL----------
>tr|A0A081SHM3|A0A081SHM3_9CHLB Silent information regulator protein Sir2 OS=Chlorobium sp. GBChlB GN=HY22_04175 PE=4 SV=1
---------------------------------------MKRIVVFSGAGLSAESGIPTFRDSDGLWEQHRIEDVASPDGWQRDPELVLDFYGKRFQKMN
--LVQPNAAHYALAELQKKFD--VINITQNIDTLLEQAGAKNVWHLHGRLDTAKCEFGTHRCLISKPIALGDTCPKC--GGRLRPDVVWFGESVDMRQPY
EELIDTASVFIGVGTSAQVYPAAGLLTLFAD-TEQKYFIDPNPAYGALYGFSVLEGKASVKLPELAKQL----------
>tr|K9ZAG9|K9ZAG9_ANACC NAD-dependent deacetylase OS=Anabaena cylindrica (strain ATCC 27899 / PCC 7122) GN=Anacy_0099 PE=4 SV=1
---------------------------------------MPKIVVFSGAGLSAESGIPTFRGTGGLWEGYKIEDVATPLGWMQNQKMVLDFYAQRFAQMQ
--ECQPNAAHFAIAELANNFD--VVCITQNIDTLLEKAGVKDVWHIHGRIDYQKCEWPEWQCEITQPVQLGDLCPKC--GKHLRPDVVWFGEAVDMRVDN
YKIQNQVDVFIVVGTSAQVYPAANLLKFFQD-VPVKYFIDPHPHNEVLAGFTVLEGKATKYLPALVESL----------
>tr|D1QVA2|D1QVA2_9BACT Transcriptional regulator, Sir2 family OS=Prevotella oris F0302 GN=HMPREF0971_03027 PE=4 SV=1
-----------------------------------MRTEASKIVFLTGAGMSVESGFKTFRGSDGLWENYPVEQIATHHGWENDPTLVTDFYNMLRRKLW
--NALPNAGHRLIRSLERDYQ--VTVITQNVDNLHERAGSSHVIHLHGELSKVCSSHDQFIEPENSDVAPGTLAKD---GSLLRPFIVFFGESVPMIAPA
AREVASADIFVIIGTSLNVYPAAGLLQYCKP-DIPIYLIDPNPVNAGYQHVKQLQMGASEGMKALIESL----------
>tr|D5EYR7|D5EYR7_PRER2 NAD-dependent deacetylase OS=Prevotella ruminicola (strain ATCC 19189 / JCM 8958 / 23) GN=npdA PE=4 SV=1
---------------------------------------MKKIVVLTGAGMSVESGLKTFRDADGLWENYPVQKVATHEGWLADPTLVTNFYNMLRKKCW
--NVQPNEGHKLVAELEKNYD--VTVVTQNVDNLHEMAGSSKVIHLHGELMKVCSSRDRYQIPDNCEIEPGTKAGD---GSLLRPFIVFFGEAVPNITIA
AEEVQEADILIIIGTSLVVYPAAGLLHYARP-DVPVYLIDPNPINAGR--VTQIQKGASEGMKELVKIL----------
>tr|R5FNU3|R5FNU3_9BACT NAD-dependent deacetylase OS=Prevotella sp. CAG:924 GN=BN812_01895 PE=4 SV=1
--------------------------------------MKKKVVFLTGAGMSVESGFKTFRGEDGLWENYPVEKVCTHEAWERDPDFVTGFYNMLRKKLW
--VAQPNEGHRLIAQMEKEYD--VSVLTQNVDNLHEKAGSTHVIHLHGDLSKVCSSNNRYIKPEDSDVKPGTKAGD---GSLLRPFIVFFNESVPMLNPA
AREAEKADVFVIIGTSLNVYPAAGLVQYTPA-NCPIYLIDPNPVT-NFRNVTQIRKGASEGMKELLTMI----------
>tr|H1HL99|H1HL99_9BACT Uncharacterized protein OS=Prevotella maculosa OT 289 GN=HMPREF9944_00943 PE=4 SV=1
-----------------------------------MKKEISKIVFLTGAGMSVESGFKTFRGSDGLWENYPVEQIATHHGWESDPVLVTNFYNMLRRKLW
--KAQPNEGHRLIKQLESSHE--VTVVTQNVDNLHEKAGSKNVIHLHGELSKVCSSKARFIEPEHSDVEPGTLAKD---GSLLRPFIVFFEESVPMIEPA
AREVAEADTFIIIGTSLNVYPAAGLIQYCKP-GIPIYLIDPNPVNMTGRHIKQITKGASEGMRVLMESL----------
>tr|G1WE32|G1WE32_9BACT Uncharacterized protein OS=Prevotella oulorum F0390 GN=HMPREF9431_02162 PE=4 SV=1
---------------------------------------MKHLVFLTGAGMSVESGFKTFRGSDGLWENYPVEQIATHEGWERDPELVTNFYNMLRKKLW
--TATPNEGHRLIASLQNDYE--VTVITQNVDNLHERAGSKKVIHLHGELAKVCSSRAQCIEPENSDVVPGSRAKD---GSLLRPFIVFFGESVPMIEPA
IAETQRADLFIVIGTSLNVYPAAGLLHYCSP-QTPIVLIDPNPVNTADRPITTLKMGASEGMRTLIAQH----------
>tr|L1NJR3|L1NJR3_9BACT Putative NAD-dependent deacetylase OS=Prevotella saccharolytica F0055 GN=HMPREF9151_00260 PE=4 SV=1
-----------------------------------MNTKSKHLVFLTGAGMSVESGFKTFRGADGLWENYPVAQVATHEGWEANPTLVTEFYNMLRQKLF
--DAKPNEGHRLIAQLEERFR--VTVITQNVDNLHECAGSSEVLHLHGELSKVCSSRDHFIRATDAVITPGTKAED---GSLLRPFIVFFGEAVPMMDAA
MALTAQADLFVVIGTSLNVYPAAGLINFVPR-GVPIIIIDPEPISTTNGGVTQIQKGASEGMKELVETL----------
>tr|E6MR76|E6MR76_9BACT Transcriptional regulator, Sir2 family OS=Prevotella salivae DSM 15606 GN=cobB PE=4 SV=1
-----------------------------------MTNKISKIVFLTGAGMSVESGFKTFRGSDGLWENYPVDEIATHHGWEDNPTKVTNFYNMLRKKLW
--NASPNEGHRLIQSLEQQYE--VTVVTQNVDNLHERAGSTHVIHLHGELSKVCSSRDEYIEPEHSDVEPGTLAKD---GSLLRPFIVFFEESVPMIAPA
AHEVTSADLLVVIGTSLNVYPAAGLLQYCRP-GVPIYLIDPNPVNTNFQHVKQLQMGASEGMKRLTELL----------
>tr|I4ZA10|I4ZA10_9BACT NAD-dependent protein deacetylase, SIR2 family OS=Prevotella bivia DSM 20514 GN=PrebiDRAFT_1343 PE=4 SV=1
----------------------------------QSLPHRQKIVVFTGAGISKESGMETFRDLDGLWKRYDPAQIATPEGFAADTEFVLNFYNEMRKMLI
--DIEPNHAHKIVAALEEWHD--VTVITQNIDDLHERAGSSHVIHVHGELTKVTSSYDRYIQPLDKAIKVGDKALD---GSQLRPYIVWFGESLPDLGAC
VQRMQQADYLLIIGTSLTVMPAAGLINYAPF-NIPKFCIDPNNLMLP-SNIEHIKEPATRGIDIFIKRL----------
>tr|J9GKK3|J9GKK3_9ZZZZ Silent information regulator protein Sir2 OS=gut metagenome GN=EVA_04006 PE=3 SV=1
--------------------------------------------------MSAESGISTFRDAGGLWDQYPVEQVATPEGYLRDPALVTKFYNEQRKQLL
--KVKPNRGHELLATLEQQYH--VTVVTQNIDNLHERAGSSHIIHLHGELTKVCSSRDQYIKPEEYEVKIGDKAGD---DTQLRPFIVWFGEAVPEIEKA
IQVVEQADIFVIIGTSLNVYPAAGLLHYVPS-QAKVYLIDPKPVD-TSRPIHIIQKGASEGVAELITLL----------
>tr|B6VYK0|B6VYK0_9BACE Putative uncharacterized protein OS=Bacteroides dorei DSM 17855 GN=BACDOR_02344 PE=3 SV=1
----------------------------------RGGLEMKNLVVLTGAGMSAESGISTFRDAGGLWDQYPVEQVATPEGYAANPKLVIDFYNERRKQLF
--AVKPNQGHELVSEMEKFFN--VTVITQNIDNLHERAGSSHIIHLHGELTKVTSSWEAYIKPEEYEIHLGDLAGD---GSQFRPFIVWFGESVPMIETA
IEYAETADIFLIIGTSLNVYPAAGLLNYVPA-NTPVYLIDPKQVP-IGRKVHVIQKGASEGMEELKKIL----------
>tr|B3JLD0|B3JLD0_9BACE Transcriptional regulator, Sir2 family OS=Bacteroides coprocola DSM 17136 GN=BACCOP_02716 PE=3 SV=1
----------------------------------RKYLPMKKLVILTGAGMSAESGISTFRDSGGLWDRYPVEQVATPEGYAANPKLVIDFYNERRKQLL
--TVKPNRGHELIAELENFFD--VTVVTQNVDNLHERAGSHHVIHLHGELTKVTSSWQKYIKPEEYEVKMGDTAAD---GSQLRPFIVWFGEAVPMIETA
IDYAEQADIFVIIGTSLNVYPAAGLLNYVPA-HVSVYLIDPKEVA-IGRHVNVIRKGASEGMCELKKML----------
>tr|S8H1T7|S8H1T7_9BACT Transcriptional regulator, Sir2 family OS=Bacteroidetes bacterium oral taxon 272 str. F0290 GN=HMPREF9012_0132 PE=3 SV=1
--------------------------------------MMKKLVVLTGAGMSAESGFSTFRDSGGLWEQYNVEDVATPQGYERDPRLVIDFYNKRRKQLQ
--DAKPNKGHELVAGLEKAYE--VTVITQNVDDLHERAGSKNVIHLHGELTKVTSTDQEYIRPEEWEVKIGDKAAD---GSQLRPFIVWFGEAVPKIEDA
VRCVERADIFLIIGTSLNVYPAAGLLNYVPY-DVPVYLIDPKEVA-IGRKVRVIRKGASEGMEEFIKVI----------
>tr|R6CUT6|R6CUT6_9BACE Transcriptional regulator Sir2 family OS=Bacteroides sp. CAG:530 GN=BN697_01888 PE=3 SV=1
---------------------------------------MKKLVVLTGAGMSAESGISTFRDSGGLWDRYPVEQVATPEGYAANPELVLNFYNERRKELL
--HVEPNEGHKLLAELERYFD--VTIITQNVDNLHERAGSHHVIHLHGELTKVTSSRNACIRPEEYDVKIGDKAAD---GSQLRPFIVWFGEAVPMIETA
VDYAEKADVFVIIGTSLNVYPAAGLLNYVPY-DVPVYLIDPKEVN-IGRKVHVIRKGASAGMEELKEIL----------
>tr|R5UI37|R5UI37_9BACE NAD-dependent deacetylase OS=Bacteroides sp. CAG:702 GN=BN759_00252 PE=3 SV=1
---------------------------------------MKKLVILTGAGMSAESGISTFRDSGGLWEQYPVEQVATPEGYRANPKLVIDFYNARRKELQ
--RVKPNRGHELIAELEKDFD--VTVITQNVDNLHERAGSHHVIHLHGELTKVTSSRDAYIKPEEWEVKMGDLAAD---GSQLRPFIVWFGEAVPMIETA
IGYAEQADIFVIIGTSLNVYPAAGLLNYVPS-RVPVYLIDPKEVT-IGRKVHVIRKGASEGMEELKNML----------
>tr|F3QV75|F3QV75_9BACT NAD-dependent deacetylase OS=Paraprevotella xylaniphila YIT 11841 GN=HMPREF9442_02100 PE=3 SV=1
---------------------------------------MKKVVVLTGAGMSAESGLSTFRDSGGLWDRYPVEDVATPEGYARNPELVTRFYNERRRQLQ
--EVEPCRGHVLLAAMEQDYD--VTVITQNVDNLHERAGSTKVVHLHGELTKVTSSLEKYIRPEEWEVKIGDRAAD---GSQLRPFIVWFGEPVPMIEAA
INITSTADVFVVIGTSLNVYPAAGLLNYVPS-HAPIYVIDPKPVAGIGGRVHHLMKGASEGVEELMVCL----------
>tr|R6YVJ3|R6YVJ3_9BACE Transcriptional regulator Sir2 family OS=Bacteroides sp. CAG:714 GN=BN762_00364 PE=3 SV=1
----------------------------------QEEVKMKNLVVLTGAGMSAESGISTFRDSGGLWDRYPVEQVATPEGYAANPKLVIDFYNERRKQLL
--EVQPNRGHELLAELEKNFK--VTVITQNIDNLHERAGSTHVIHLHGELTKVTSSWQKYIRPEEFEVKIGDKAGD---GSQLRPFIVWFGEAVPMIETA
IDYAEQADIFVIIGTSLNVYPAAGLLNYVPR-NVPVYLIDPKEVP-LGRSVHVIQKGASEGMAELKKML----------
>tr|A0A0R2H0V1|A0A0R2H0V1_WEIVI Uncharacterized protein OS=Weissella viridescens GN=IV50_GL000564 PE=4 SV=1
----------------------------------EKIITKSPTVFIIGAGLSTASGIQDFASLQA---NFDTSALLSREAYYQHYWEQHDFM-VKYLMNQ
--TAQPNIGHQWIADLSHHQG--IKVISQNIDNLLEQAHADNLLKIHGSIDHFIDRN-VS----ETEYQYLPHTED---NLMILPDIVFYGENVKGMDQA
LSWMQTAKNVVIVGTRLNVAPVNQLTLWAKK-LEHIFVVNQEPVHPLNVPVTQITTDISD----WLQN-----------
>tr|C0EHQ1|C0EHQ1_9FIRM NAD-dependent protein deacetylase OS=[Clostridium] methylpentosum DSM 5476 GN=cobB PE=3 SV=1
--------------------------------------QSESIVFFGGAGVSTESGIPDFRSVDGLYHQYPPEQIISRSFYDTRTVE---FYEFYRDRML
FPDAKPNAAHKKLAALEQAG-KLKAVVTQNIDGLHQMAGSQNVLELHGSVHRNYCRRCGKFYD-LDFLHGVPTCS-CG--GEIKPDVVLYEESLDTMRAA
VEAIASADMLIIGGTSLVVYPAAGMVNY-YK-GDRLVLINKGSTSYDS-RDLFLQGKIGEILGQIK-------------
>tr|E3HAW9|E3HAW9_ILYPC NAD-dependent protein deacetylase OS=Ilyobacter polytropus (strain DSM 2926 / CuHBu1) GN=cobB PE=3 SV=1
--------------------------------------KSNNIVFFGGAGVSTESNIPDFRSATGLYAH-SPEYLLSRTYFDSNTEE---FYKFYKENLI
FKDAEPNDAHYALAKLEELG-KLKAVITQNIDGLHQKAGSKKVYELHGSVIRNYCMKCNEYHD-LDYISTVPRCRKCG--GLVKPDVTLYEEMLDVFGGA
IDCISKADVLIVGGTSLVVYPAASLVEY-YK-GSKLVLINKGATSYDN-KSLVIDARIGEVLKEVT-------------
>tr|R7K8Z2|R7K8Z2_9FIRM NAD-dependent protein deacetylase OS=Acidaminococcus sp. CAG:917 GN=cobB PE=3 SV=1
--------------------------------------QSSNAVFFGGAGVSTASGIPDFRGKGGLYMGLPAEVYLSHSFFVRNTEK---FFEFYRSKML
YPNAKPNVVHSTLASLEKAG-KLRAVITQNIDGLHQMAGSRNVIELHGSVNRNYCLDCGEFYG-VDY--GVPKCAKCG--GVVKPDVVLYEEPLSEWSRA
YMAIEEADLIIVGGTSLSVYPASSLLYN-TN-GKILCLINNQPTSFDS-STLVIRDDLKRVFESIS-------------
>tr|X8HSC1|X8HSC1_9FUSO NAD-dependent protein deacetylase OS=Fusobacterium sp. OBRC1 GN=cobB PE=3 SV=1
----------------------------------------KYLVFFTGAGVSTDSGLKSFRGKDGLYSTYRPEEVLSSDFFYSHRNI---FMEYVENELN
INGIKPNKGHLALAELERIG-LLKAVITQNIDDLHQMAGNKNVLELHGSLKRWYCLECGKTAD-NN------FSCECG--GIVRPDVTLYGENLNVVNEA
IYQLEQADTLIVAGTSLTVYPAAYYLRY-FK-GKNLVIINNENTQYDN-ESLVLNTNFADTMDKVI-------------
>tr|C3WDZ8|C3WDZ8_FUSMR NAD-dependent protein deacetylase OS=Fusobacterium mortiferum ATCC 9817 GN=npdA PE=3 SV=1
----------------------------------------NYVVFFTGAGASTDSGLADFRGKNGLYNEYEPEEILSHDFFFLHRDI---FNKYLTEKLS
INNIKPNNGHLAIAKLEEMG-KVKAVITQNIDNLHQDAGSKKVLELHGTLKRWYCLKCGKTSD-KD------FICECG--GVVRPDVTLYGEMLNVTSEA
IREIEKADTLIIVGTSLTVYPAAYYIEY-FK-GKNLIILNETPTSRDD-ITLVIRERFAQVMTEVM-------------
>tr|C6JPG0|C6JPG0_FUSVA Putative NAD-dependent deacetylase OS=Fusobacterium varium ATCC 27725 GN=FVAG_00725 PE=4 SV=1
----------------------------------------KYIVVFTGAGASTDSGLRDFRGKNGLYNDYEPEEILSHDFFFSHRDI---FDRYLIEKLS
INDIKPNAGHKAIAELEKMG-KVKAVITQNIDDLHQAAGSKNVLELHGTLKKWYCLSCGKIEN-TS------FNCECG--GIVRPQVTLYGEMLDITSKA
ISEIEKADTLVIIGTSLTVYPAAYYLNY-FS-GKSLVILNETPTSQDG-KQLVIRDNFSKVMIETM-------------
>tr|D6LEY3|D6LEY3_9FUSO NAD-dependent protein deacetylase OS=Fusobacterium periodonticum 1_1_41FAA GN=cobB PE=3 SV=1
----------------------------------------KHLVFFTGAGVSTESGLKSFRGKDGLYSSYRPEEVLSSDFFCSHRKI---FIEYVEEELN
INGIKSNKGHLVLAELEKMG-ILKAVITQNIDDLHQMAGNKNVLELHGSLKRWYCLSCGKTSN-KN------FSCDCG--GIVRPDVTLYGENLNVVNEA
IYQIEQADTLIVAGTSLTVYPAAYYLRY-FR-GKNLVIINNESTQYDG-ESLVLKTNFADTMEKVL-------------
>tr|U2EFR2|U2EFR2_9FIRM NAD-dependent protein deacetylase OS=Clostridiales bacterium oral taxon 876 str. F0540 GN=cobB PE=3 SV=1
--------------------------------------NSSSIVFFGGAGVSTESNIPDFRSDNGLYKEYEPETILSKSFFINHTED---FFSFYKSKMI
YKNAKPNKAHIALAKLEQIG-KLKAVITQNIDGLHQLSGSKNVLELHGSIHRNHCIKCGRHYD-LDYINNIPYCEFCG--GIIKPDVVLYEENLDILSSA
TSYISKSDTLIVGGTSLAVYPAAGLINY-YR-GNNLILINKSETPYDS-KNLIFHDSIGDILSSVI-------------
>tr|W6NE59|W6NE59_CLOTY NAD-dependent protein deacetylase OS=Clostridium tyrobutyricum DIVETGP GN=cobB PE=3 SV=1
--------------------------------------SSDNIVFFGGAGVSTESNIPDFRSEAGLYKTYPPEVMLSHSFFKSHPED---FFDFYRAKMV
YKNAKPNNAHYALAELEKRG-KLKAIVTQNIDGLHQMAGSKNVLELHGSIHRNHCTKCGKFFD-LDYLNSIPKCDDCG--GLVKPDVVLYEEGLDILNSA
IQYIKNADVLIVGGTSLVVYPAAGLVDY-FK-GKYLVLINKSSTQYDY-KNIAIHDSIGKVLKSAI-------------
>tr|A3DBH9|A3DBH9_CLOTH NAD-dependent protein deacetylase OS=Clostridium thermocellum (strain ATCC 27405 / DSM 1237 / NBRC 103400 / NCIMB 10682 / NRRL 
--------------------------------------KSGSIVFFGGAGVSTESGIPDFRSSTGIYGQYPPEVMLSHSFFMEHTEE---FFEFYKEKMI
YKDAKPNAAHIALAKLEKHG-KLKAVITQNIDGLHQAAGSENVIELHGSIHRNRCMKCNESYD-LEYLNTVPLCKKCN--GIVKPCVVLYEEPLDSIDRA
VDYIEKADMLIVGGTSLAVYPAAGLIQY-YR-GDRLVLINKSPTPYDR-RNLIIRDSIGAVLGSVV-------------
>tr|W4V5Y3|W4V5Y3_9FIRM NAD-dependent protein deacetylase OS=[Clostridium] straminisolvens JCM 21531 GN=cobB PE=3 SV=1
--------------------------------------KSSSIVFFGGAGVSTESGIPDFRTDTGIYNQYPPEVMLSHSFFMEHTAE---FFEFYKDKMI
YKHSKPNAAHFALAELEKRG-KLKAVITQNIDGLHQAAGSKNVIELHGSVHRNNCMNCSESYD-LEYLNIVPQCRKCN--GIVKPCVVLYEEPLDSINKA
VDCIETADMLIVGGTSLAVYPAAGLIRY-YR-GDRLVLINKSETPYDG-KDLIIRDSIGKVLSSVI-------------
>tr|B9DXH0|B9DXH0_CLOK1 NAD-dependent protein deacetylase OS=Clostridium kluyveri (strain NBRC 12016) GN=cobB PE=3 SV=1
--------------------------------------SSENIVFLGGAGVSTESNIPDFRSEAGIYKTYPPEVMLSHTFFMSHTED---FFDFYRKKMI
YKDAKPNDTHYALAELEKRG-KLKAIITQNIDGLHQMAGSHNVLELHGSIHRNYCTRCNKFFD-LDYIKLIPKCDKCN--GLVKPDVVLYEESLDVLNNS
VEYIRKADILIVGGTSLVVYPAAGLVDY-FN-GSNLVLINKSTTPYDN-KNIVIHDSIGKVLKSIL-------------
>tr|D8GKA5|D8GKA5_CLOLD NAD-dependent protein deacetylase OS=Clostridium ljungdahlii (strain ATCC 55383 / DSM 13528 / PETC) GN=npdA PE=3 SV=1
--------------------------------------SSTNIVFLGGAGVSTESQIPDFRSETGLYKTYPPEVMLSHSFFMSHTED---FFDFYRAKMI
YKDAKPNDAHYALAELEKMG-KLKAIVTQNIDGLHQMAGSNNVLELHGSIHRNHCTKCGKSFD-LDYLNLIPKCDKCN--GTIKPDVILYEESLNTLNKS
VEYIQQADMLIVGGTSLIVYPAAGLINY-FK-GKYLVLINKSSTSYDN-ENIVIHDSIGKVLKSIL-------------
>tr|R4K6H2|R4K6H2_CLOPA NAD-dependent protein deacetylase OS=Clostridium pasteurianum BC1 GN=cobB PE=3 SV=1
--------------------------------------NSNNIVFFGGAGVSTESSIPDFRSESGLYKTYAPEIMLSHSFFINHTED---FFDFYRAKMI
YKEAKPNPAHYALAELERKG-KLKAVITQNIDGLHQMAGSKKVLELHGSIHRNYCTNCNKFFD-LEYLDIIPKCDMCG--ETIKPDVVLYEEGLNIINES
VRFISNADVLIVGGTSLVVYPAAGLIDY-FK-GKKLILINKASTPYDR-RDLVINDSIGKILKGVL-------------
>tr|V2XUZ6|V2XUZ6_9FIRM NAD-dependent protein deacetylase OS=Firmicutes bacterium ASF500 GN=cobB PE=3 SV=1
--------------------------------------ESQRIVFFGGAGVSTESGIPDFRSVDGLYNQWPPEEILSRTFFDAQPEE---FYRFYRDKML
CLDAQPNAAHKKLAELEKAG-RLQSVVTQNIDGLHQKAGSQRVWELHGSVHRNYCMRCRKPYS-VADK-GVPRC-ACG--GTVKPDVVLYEEGLDTIEGA
VSDIRGADLLIIGGTSLAVYPAAGLINY-FR-GNRLVLINKSPTPYDD-RSLAINQPIGQVLGQIK-------------
>tr|D3E1P6|D3E1P6_METRM NAD-dependent protein deacetylase OS=Methanobrevibacter ruminantium (strain ATCC 35063 / DSM 1093 / JCM 13430 / OCM 146 / M1) G
--------------------------------------SSDNIVFFGGAGVSTESGIPDFRSESGIFKSDVPENLVSHTYYSDHTEE---FFEYYKDTLV
FDGAKPNPAHLKLAELEEKG-KLRAVITQNIDGLHQKAGSKNVLELHGSIHRNYCQICNKEYS-LDFLKGIPRCD-CG--GVVKPDVVLYEEPLDILAYA
IDYIQNADTLIIGGTSLVVYPAAGLINY-FH-GGNLVLINKSETGFDY-MNLVINEPIGETLSQIR-------------
>tr|A5UM64|A5UM64_METS3 NAD-dependent protein deacetylase OS=Methanobrevibacter smithii (strain PS / ATCC 35061 / DSM 861) GN=cobB PE=3 SV=1
--------------------------------------ASDNIVFFGGAGVSTESGIPDFRSESGIFKSDTPERLVSHSYYLEHTDK---FFSYYKDCLI
FPEAEPNPAHYTLARLEKEG-KLKAIITQNIDGLHQKAGSKNVLELHGIVYRNYCEICKKKYD-LNFLEGIPHCT-CG--GIIKPDVVLYEEALDILNKS
AQYIMSADTLIVGGTSLVVYPAAGLINY-FK-GKNLVLINKSQTDYDN-LTLVINEAIRETLAKIK-------------
>tr|A0A0N8PV49|A0A0N8PV49_9BACL NAD-dependent deacetylase OS=Paenibacillus sp. A3 GN=QJ48_07030 PE=4 SV=1
--------------------------------------DSKNIVFFGGAGTSTESQIPDFRSATGLYQTFPPEVMLSRSFFMERTAE---FFDFYRACMV
HREAKPNAAHEVLAQLEQTG-KLRAVVTQNIDGLHQMAGSRHVLELHGSVHRNYCMGCGKFFD-LDHTSMVPRCDACG--GIVKPDVVLYEESLDILSKA
RKHIAEADVLIVGGTSLTVNPAAALVGE-YG-GDKLILINQSSTPYDS-RTHVIRDSIGKVLKALV-------------
>tr|K1ALD6|K1ALD6_9STRE NAD-dependent protein deacetylase OS=Streptococcus sp. GMD4S GN=cobB PE=3 SV=1
--------------------------------------QSQRIVFFGGAGVSTESNIPDFRSSDGVYSHFTAEQLVSRTMFERYPED---FFDFYKKYLI
YPEAKPNAAHTYLAALEKTG-KLKAVVTQNIDSLHEMAGSQKVFKLHGSADRNYCLGCHRFYD-LTALAPVPNCLDCG--KVVKPDVTLYEESLDVFSQA
AQAIRQADLLIIGGTSLVVYPAASLVNY-FS-GTNLVLINKTSIPQDS-QTLVIEGKIGEVFSKLR-------------
>tr|E9FL43|E9FL43_9STRE Putative NAD-dependent deacetylase OS=Streptococcus sp. M334 GN=HMPREF0851_00174 PE=4 SV=1
--------------------------------------QSQRIVFFGGAGVSTESNIPDFRSSDGIYSLFTAEQLVSRTMFERYPED---FFDFYKKYLV
YPDAKPNLAHDYLASLEKTD-KLKAIVTQNIDSLHEMAGSQKVLKLHGSADRNYCLGCHRFYD-LTALEPVPYCLDCR--KVVKPDVTLYEEALDVFSCA
ARAIQQVDLLIIGGTSLVVYPAASLVNY-FS-GSNLVVINKSSTPQDS-QDLVIEGKIGEVFSKLR-------------
>tr|A0A0M4K025|A0A0M4K025_PROAA NAD-dependent protein deacetylase OS=Propionibacterium acnes GN=cobB PE=3 SV=1
--------------------------------------STSTV-FFGGAGMSTESGIPDFRSAGGLYTTFPAEYMLSHSCLVEHPAE---FFDFYRTYLI
HPQARPNAGHRALVALEQAG-ELSTIITQNIDGLHQEAGSRQVIELHGSVHRNRCLDCGRDHP-LSVMDGIPRCSCVG--GMVRPEVVLYEESLRDLDDA
ITAISAADLLIVGGTSLNVYPVAALLRF-FR-GRHLALINREATGYDR-ADLVIHDGLGKTLSAVQ-------------
>tr|K7RRM7|K7RRM7_PROA4 NAD-dependent protein deacetylase OS=Propionibacterium acidipropionici (strain ATCC 4875 / DSM 20272 / JCM 6432 / NBRC 12425 / 
--------------------------------------GARRAVFFGGAGVSTESGIPDFRSAGGLYTTYPAEYMLSHECFEAEPQL---FMDFYRQYLV
HPDARPNRAHRALAAMEGQG-RLEAVITQNIDGLHQDAGSARVIELHGSVHRNHCMGCGRHYG-LDV--GITVCHACG--QMIRPDVVLYGETLDVIDDA
LAAIQAADVLIVGGTSLNVYPAAGMIRF-FR-GTHLVLINLETTPYDS-DDLVIHERIGEALGEAL-------------
>tr|C7N3G1|C7N3G1_SLAHD NAD-dependent protein deacetylase OS=Slackia heliotrinireducens (strain ATCC 29202 / DSM 20476 / NCTC 11029 / RHS 1) GN=cobB PE
--------------------------------------KPGGMVFFGGAGVSTESGIPDFRSPNGLYAQIPPEDMVSHSYFVQHTAS---FFEFYCDRMI
APDAEPNPAHLKLAELEARG-TLSAVITQNIDGLHQKAGSKNVLELHGSTLRNFCEDCHEPYS-LDELAGVPHCKKCG--GIIKPDVVLYEEPLDIMMRS
LMAIASADLLVIAGTSLAVYPAAGLIDY-FK-GSHLAIVNMSPTPRDK-QDLCISAPVGQVFSW---------------
>tr|G5GIT1|G5GIT1_9FIRM NAD-dependent protein deacetylase OS=Johnsonella ignava ATCC 51276 GN=cobB PE=3 SV=1
--------------------------------------LSDNIVFFGGAGVSTESGIPDFRSQDGLYSMYPPERILSHSFFMSMRDE---FYRFYRDKMI
YTQAKPNDAHIALAKLEQIG-KLKAVITQNIDGLHQDAGSKNVIELHGSIRRNYCMKCGKSYE-LDKI-GVPKCE-CN--GDIKPDVVLYEEGLDVLNKA
IDFINAAQILIIGGTSLAVYPAAGLVNY-FK-GSKLVLINKTPTPMDS-GDLVFHGSIGQVLKSAI-------------
>tr|R6XEX9|R6XEX9_9FIRM NAD-dependent protein deacetylase OS=Firmicutes bacterium CAG:313 GN=cobB PE=3 SV=1
--------------------------------------NSNNIVFFGGAGVSTESNIPDFRSDTGLYKQYNAEEILSRTFFNNHKDI---FYKFYFDEML
HPNARPNKAHLALATLEKEG-KLRAVITQNIDGLHQDAGSKNVIELHGSVRRNHCIKCRGFYN-EEEIK-QGICPVCG--SYIKPDVVLYEESLNVVDKA
IYYISTCDVLIVGGTSLSVYPAASFIRY-FK-GKYLILINRDKTSYDD-YSIVIHDSIGKVLESVI-------------
>tr|F2BRU4|F2BRU4_STRSA NAD-dependent protein deacetylase OS=Streptococcus sanguinis SK1057 GN=cobB PE=3 SV=1
--------------------------------------QSQNIVFFGGAGVSTESNIPDFRSSDGIYSVFTAEQLVSHTMFERYPKE---FFDFYKKYLL
YPDAKPNAAHVYLADLEKAC-KLKAVVTQNIDSLHEMAGSKKVLKLHGSADRNYCLNCQRFYD-LDGLATIPRCLDCG--GIVKPDVTLYEEPLDVFQQA
AQAIHQADLLIIGGTSLVVYPAASLIQY-FA-GKHLVVINKTNIPQDS-QDLVIEGKIGEVLGKFK-------------
>tr|E8JSI0|E8JSI0_STRCR NAD-dependent protein deacetylase OS=Streptococcus cristatus ATCC 51100 GN=cobB PE=3 SV=1
--------------------------------------QSQNIVFFGGAGVSTESNIPDFRSSDGIYSVFTAEQLVSHTMFERYPQE---FFDFYKKYLL
YPDAKPNAAHAYLAHLEKTG-KLKAVVTQNIDSLHEMAGSKNVLKLHGSADRNFCLNCQRFYD-LEALATVPYCPDCG--GVIKPDVTLYEESLDTFQQA
AQAIHQADLLIIGGTSLVVYPAASLIQY-FA-GKHLVVINKTSIPQDK-QDLIIEGKIGEVLEKLR-------------
>tr|A0A0F2CN58|A0A0F2CN58_STRGN NAD-dependent protein deacetylase OS=Streptococcus gordonii GN=cobB PE=4 SV=1
--------------------------------------QSQDIVFFGGAGVSTESNIPDFRSSDGIYSVFTSEQLVSHTMFERYPQE---FFDFYKKYLL
YPDAKPNAAHAYLADLEKEG-KLKAVVTQNIDSLHEMAGSKKILKLHGSADRNYCLNCQRFYD-LDGLATIPYCLDCG--GIVKPDVTLYEEPLDVFQQV
AQTIHEADLLIIGGTSLVVYPAASLIQY-FV-GNHLIVINKTSIPQNS-QNLVIEGKIGQVFSQLR-------------
>tr|W8TK34|W8TK34_EUBAC NAD-dependent protein deacetylase OS=Eubacterium acidaminophilum DSM 3953 GN=cobB PE=3 SV=1
--------------------------------------SSRDIVFFGGAGVSTESNIPDFRSENGLYRTYPPETMLSRSFFDAHTLE---FYEFYREKIL
YPDAKPNKAHYALAQMERNG-NLKAIVTQNIDGLHQAAGSRNVIELHGSVLRNYCTSCKAFYD-LDYISTVPMCSACR--GLIKPDVVLYEEALDVIEDA
VSAIAQADTLIVGGTSLVVYPAAGLLRY-FK-GSSLVLINKSSTQYDS-RSLVIKDSIGSVLSKAV-------------
>tr|R5AD16|R5AD16_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. CAG:1013 GN=cobB PE=3 SV=1
----------------------------------------KRTIFLGGAGVSTASGIPDFRSAHGLYRQRSYEEMLSHTYFVRHMEE---FYDFMRNVML
YPDAKPNRAHYALAKLEREG-KLRAVITQNIDGLHQMAGSKSVIELHGNENRYYCLSCGKRYD-MSCT-GVPRC-ECG--GTIRPDVVLYEESLNDLRFA
IRYAQETDLMVVAGTSLVVYPVAGLVEY-LSPGARLVILNRDPTPYDS-RDLVIREDLVEVLAHCA-------------
>tr|R6YCR4|R6YCR4_9FIRM NAD-dependent protein deacetylase OS=Firmicutes bacterium CAG:94 GN=cobB PE=3 SV=1
----------------------------------------RRAAFLGGAGVSTASGIPDFRSAHGLYQQLSYEEMLSHGYFVRHTAE---FYDFLRGVML
YPDAKPNGAHYALAQLERQG-KLRAVITQNIDGLHQMAGSRNVLELHGSENRYTCLACGKRYD-MTCT-GVPRC-ACG--GTIRPDVVLYGESLNDLRQA
IRYVEEADLLLVAGTSLVVYPVAGLVEY-VRPGAKLVILNRDPTPYDS-RDLVLRGDLVEELAHCV-------------
>tr|S0J1Q5|S0J1Q5_9FIRM NAD-dependent protein deacetylase OS=Eubacterium sp. 14-2 GN=cobB PE=3 SV=1
--------------------------------------RSDNIVFFGGAGVSTESGIPDFRSVDGLYNQYPPETILSHTFYRQNPEE---FYRFYRDKML
CLNAEPNMAHKKLAELEAAG-KVKAVITQNIDGLHQLAGSRKVLELHGSVHRNYCESCHHLYD-AAYL-GVPHCQECG--GEIKPDVVLYEEGLDTIQEA
VYYISQADMLIIGGTSLAVYPAAGLVDY-YQ-GNKLVLVNKTPTPRDS-MDLVLQESIGELFGKIT-------------
>tr|A5Z3M1|A5Z3M1_9FIRM NAD-dependent protein deacetylase OS=Eubacterium ventriosum ATCC 27560 GN=cobB PE=3 SV=1
--------------------------------------GSDNIVFFGGAGVSTESGVPDFRSVDGLYNQYPPETILSHTFYRRNPEE---FYRFYHNKML
FPDAKPNAAHKALAKLEKKG-KLKAVVTQNIDGLHQAAGSETVYELHGSVHRNYCESCGKFYG-LKEMAGVPKCS-CG--GIIKPDVVLYEEGLDTIRKS
IEAISNADVLIIGGTSLAVYPAAGLIDY-YR-GNKLVLINKSSTPKDS-RDLIINDAIGKVLGQIV-------------
>tr|A0A0J6WX95|A0A0J6WX95_9FIRM NAD-dependent protein deacetylase OS=Megasphaera cerevisiae DSM 20462 GN=cobB PE=3 SV=1
--------------------------------------HSDNIVFFGGAGVSTESGIPDFRSVDGLYNQYPPETILSHSFYQNNPEE---FYRFYRDKML
CLDAKPNMAHIKLAALEKAG-KLKAVVTQNIDGLHQKAGSKNVLELHGSVHRNYCQHCHHFFD-AEYL-GVPKCDACG--GPIKPDVVLYEEGLDVIEQA
LYYISHADMLIIGGTSLVVYPAAGLIRY-YN-GHKLVLINKSSTDLDG-SDLVIRGPIGKVFGHIK-------------
>tr|R6GGD1|R6GGD1_9FIRM NAD-dependent protein deacetylase OS=Eubacterium sp. CAG:192 GN=cobB PE=3 SV=1
--------------------------------------GSDNIVFFGGAGVSTESGVPDFRSVDGLYNQYPPETILSHSFYRRNPEE---FYRFYRNKML
FPNAEPNMAHKALAKLEEMG-KLKAVITQNIDGLHQAAGSKNVYELHGSVHRNHCQDCGKFYG-FDQYEGIPRCQ-CG--GIIKPDVVLYEEGLDTIQLS
VEAIAKADVLIIGGTSLAVYPAAGLVDY-YR-GNKLVLINKSKTQKDQ-RDLVINQPIGEVLGQVV-------------
>tr|R6BVU4|R6BVU4_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. CAG:510 GN=cobB PE=3 SV=1
--------------------------------------ESHYIVFFGGAGVSTESGIPDFRSVDGLYHQYPPETILSHTFYRRNPEE---FYRFYKNKML
FLDAKPNMAHKKLAQWEAEG-KLKAVITQNIDGLHQAAGSKNVLELHGSVLRNYCEDCGAFYD-VDYK-GVPHCEKCG--GMIKPDVVLYEEGLNTVQKA
IRAISNADLLIIGGTSLVVYPAAGLINY-FR-GKHLVLVNKSATDRDS-EDLLLSASIGEVFGQLK-------------
>tr|X8HC65|X8HC65_9STRE Transcriptional regulator, Sir2 family OS=Streptococcus sp. AS20 GN=HMPREF1514_1632 PE=4 SV=1
--------------------------------------SSQNIVFFGGAGVSTESGIPDFRSSNGIYNIFTAEQLVSHTMFERYPEQ---FFDFYKKHLI
YPDARPNVAHDYLVHLEKTG-KLKAIVTQNIDSLHEIAGSKNVLKIHGSVDRNYCTNCHRFYD-LEDLRTIPYCETCG--YIVKPDVTLYEESLNVFSQA
IQAISRADLLIIGGTSLVVYPAANLVHY-FQ-GRQLVLINKSNTVQDN-QNLVIKGKIGEVLSKVW-------------
>tr|I0SCQ6|I0SCQ6_STRAP NAD-dependent protein deacetylase OS=Streptococcus anginosus subsp. whileyi CCUG 39159 GN=cobB PE=3 SV=1
--------------------------------------SSQNIVFFGGAGVSTESGIPDFRSSNGIYNIFSAEQLVSHTMFERYPEH---FFDFYKKYLI
YPNAKPNVAHEYLAYLEKLG-KLKAIVTQNIDSLHEMAGSRNVLKIHGSVDRNFCTNCHRFYD-LEDLKIIPYCETCG--CVVKPDVTLYEEPLNVFSQA
IQVISQADLLIIGGTSLVVYPAANLVHY-FQ-GRHLVVINKNNVLQDS-QDLVIKGKIGEVLGKTW-------------
>tr|T1ZEQ6|T1ZEQ6_STRIT NAD-dependent deacetylase OS=Streptococcus intermedius B196 GN=SIR_0831 PE=4 SV=1
--------------------------------------NSQNIVFFGGAGVSTESAIPDFRSSNGIYNIFTAEQLVSYTMFEHYPKQ---FFDFYKKYLI
YPDAKPNVAHIYLAHLENVG-KLKAIITQNIDSLHEMAGSKNVLKLHGSVDRNYCTNCHRFYD-LEDLKSIPYCETCG--HIVKPDVTLYEESLDVFNQA
IQAISRSDLLIIGGTSLVVYPAASLVQY-FQ-GRQLVIINKSKVVHDN-QSLIIEGRIGEVFSKVW-------------
>tr|F3A0R1|F3A0R1_9BACL NAD-dependent protein deacetylase OS=Gemella haemolysans M341 GN=cobB PE=3 SV=1
--------------------------------------SNDNIVFFGGAGVSTESDIPDFRSANGVFSVFTPEQLVSRTMFVKYPVD---FFDFYKKHLV
YPDAKPNNAHYYLAELEKQG-KLKAVVTQNIDTLHEQAGSKNVLKLHGSVDANYCTKCKSFYN-LEDLAEIPSCDKCG--GVIKPYVTLYEEELDVFNSA
INFIEKADVLIIGGTSLSVYPAANLLNY-FK-GKHLIVINKTSTPQDN-MDLVINGKIGEVFSKLE-------------
>tr|F3A7S7|F3A7S7_9BACL NAD-dependent protein deacetylase OS=Gemella sanguinis M325 GN=cobB PE=3 SV=1
--------------------------------------KSNNIVFFGGAGVSTESNIPDFRSANGIFSIFTPEQLVSRTMFERYPED---FFDFYKKNLI
YPDAKPNAAHYYLAKLEKMG-KLKAVITQNIDTLHEQAGSKNVLKLHGTVDANYCTKCGAYYN-LEQLNEIPRCDKCS--GVIKPYVTLYEEELDTFNSA
IRYIQEAEVLIIGGTSLSVYPAANLIQY-FR-GKYLVVINKTKTPQDN-MDLVINDSIGKVCKELD-------------
>tr|E5V1Q1|E5V1Q1_9BACL NAD-dependent protein deacetylase OS=Gemella morbillorum M424 GN=cobB PE=3 SV=1
--------------------------------------ESNNIVFFGGAGVSTESNIPDFRSANGIFSVFTPEQLVSRTMFEKYPED---FFKFYKEHLI
YPDAKPNKAHYYLAELENKG-KLRAVITQNIDTLHEIAGSKNILKLHGTVDSNYCRKCGKHYN-LEELAIIPLC-ECG--GIIKPYVTLYEEELDVFSSA
IKYIEQAEVLIIGGTSLSVYPAANLIRY-FR-GKNLVVINKTSTPQDR-MTLVISGKIGEVFEKIN-------------
>tr|R6DMT3|R6DMT3_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. CAG:242 GN=cobB PE=3 SV=1
--------------------------------------QSQRIVFFGGAGVSTESQIPDFRSDDGLYGDYPPETMLSHSFFEQHTKE---FFEYYFDKMV
YPDAKPNPAHIALAKLEQMG-KLSAVITQNIDGLHQMAGSRRVCELHGSVHRNFCINCGKKYN-LSQLEGVPRCS-CG--GIIKPDVVLYEEPLDVMAGA
ISYIMAADLMIVGGTSLAVYPAAGLLQY-YQ-GKELVLINKTQTPYDR-RSLVIRDNIGQVMEQAL-------------
>tr|H3NF37|H3NF37_9LACT Uncharacterized protein OS=Dolosigranulum pigrum ATCC 51524 GN=HMPREF9703_01168 PE=4 SV=1
----------------------------------------HRIVFFGGAGVSTASGIPDFRSSAGLYAELPAEEIVSASFFRKNPVQ---FFQFYFDKLV
YPEAKPNIAHQFMAQLEEQG-KNIQIVTQNIDNLHKQAGSSHVHHLHGTTEHNYCINCGRYYN-YEEILGIPRCSADQ--GIVRPDVTLYGEQLDVVDQA
IRVMKEAEVLIVAGTSLVVYPAAGLIDY-FN-GQHAIVINNQPIRTHR-LPLLFIQDMTDVFSVLS-------------
>tr|R6BK60|R6BK60_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. CAG:169 GN=cobB PE=3 SV=1
--------------------------------------NSSHIVFFGGAGVSTESNIPDFRSEDGLYGSYPPETMLSHSFFKRHTEQ---FFEYYFDRMV
YPQAKPNAAHYALAELEAQG-KLSAVVTQNIDGLHQQAGSKRVYELHGSVLRNHCIRCGASYS-LEQLEGVPRCS-CG--GVIKPDVVLYEESLDVLEGA
VRHIMAADLLIVGGTSLAVYPAAGLLQY-YG-GRELVLINKTETPYDR-KSLVIRQPIGKVLSKAV-------------
>tr|W0FJX1|W0FJX1_9BACT NAD-dependent deacetylase OS=uncultured bacterium Contig87 PE=4 SV=1
----------------------------------------RRIVFFGGAGVSTASGIPDFRSAEGLYTELNPEMILSKSFFYLQTEA---FFDFYRKHML
FPDARPNAAHCFLYELEKRD-RLRGIVTQNIDGLHRAAGNIRVYELHGNVHENYCMECNASYP-MEHLRGIPHCE-CG--GVIKPNVVLYGEPLEVCIGA
RREITNADTLIVAGTSLSVEPAASFTED-FR-GKHLVVINREPTPADG-RELVIRGDAAEVCEWLM-------------
>tr|H1HWU6|H1HWU6_9FIRM NAD-dependent protein deacetylase OS=Stomatobaculum longum GN=cobB PE=3 SV=1
--------------------------------------KSRRIVFFGGAGVSTESGIPDFRSADGLYAEYPPEQIVSHSFFLAHTEQ---FYDFYKERML
YPDAEPNAAHLALAALERQG-KLSAVITQNIDGLHEKAGSKRVLPLHGTVLKNHCLRCGKFYS-LAELSTVPHCD-CG--GIIKPDVVLYEEALDLLTEA
ARRIAEADLLIVGGTSLAVYPAAGLLRY-FG-GRHLVVINRSATPADR-DDLVIQAPIGEVLSKAL-------------
>tr|A0A090ZLS6|A0A090ZLS6_PAEMA NAD-dependent protein deacetylase OS=Paenibacillus macerans GN=cobB PE=3 SV=1
--------------------------------------ESGRIVFFGGAGISTESGIPDFRSAAGIYQTYSPEEILSRRFFDRHPEV---FFDFYKSKMI
HPEARPNPAHLFLADLERAG-KLDAVITQNIDGLHQLAGSRKVLELHGSIHRNTCMTCGRRYT-LEEMSIVPRC-ECG--GIIKPDVVLYGESLDVIEAA
VSAIAAADLLLIGGTSLTVQPAAHLVTY-FR-GDKTVLVNASSTAYDQ-RDLLITEPIGAVFGEVG-------------
>tr|C6IZS3|C6IZS3_9BACL NAD-dependent protein deacetylase OS=Paenibacillus sp. oral taxon 786 str. D14 GN=cobB PE=3 SV=1
--------------------------------------ESSNIVFFGGAGVSTESGIPDFRSAAGIYQMYAPEEILSRRFFDRHPDV---FFDFYKTKML
HPEAQPNAAHRCLAELERAG-KLSAVVTQNIDGLHQQAGSRRVLELHGSVHRNTCMECGRTYT-LKDMDVVPRC-SCG--GIIKPDVVLYGENLNVIQDT
VTAIAGADLLVIGGTSLTVQPAAHLVTY-FR-GERTVLINASSTAYDN-RDLLITEPIGEVLGAVS-------------
>tr|C4XFR7|C4XFR7_MYCFP Putative uncharacterized protein OS=Mycoplasma fermentans (strain ATCC 19989 / NBRC 14854 / NCTC 10117 / PG18) GN=MBIO_0724 PE=
----------------------------------------KHIVFFSGAGVSTASGIPDFRSADGLYSKMNPESILSRSFWRKNKKD---FYEYYFSNIA
FDNIKPNIIHETVASWCNKN-KC-HVITQNIDNLDIKAGNKYVIELHGNINRNYCLLCGKFYD-LAQIHGIPTCK-CG--GVINPDVVLYEDPLMSTNDA
AEAISNSDLLIIAGTSLSVYPAASYIHF-YQ-GKRIVILNKDTSRYENSEILLFNENMKDVFENLA-------------
>tr|R5IVY3|R5IVY3_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. CAG:7 GN=cobB PE=3 SV=1
--------------------------------------ESDNIVFFGGAGVSTESGIPDFRSVDGLYNQYPPERIISHSFYIQNPEE---FYRFYKDRML
FPDAKPNAAHKALAKLEQEG-KLKAVITQNIDGLHQMAGSKEVLELHGSVHRNYCTRCGQFYD-LDYRNGVPTCT-CG--GRIKPDVVLYEEGLDTIQKS
IDYIRNADMLIIGGTSLVVYPAAGLIDY-YR-GNKLVLINKSVTSRDS-QDLVISDSIGKVLGTVV-------------
>tr|R6WXD1|R6WXD1_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. CAG:349 GN=cobB PE=3 SV=1
--------------------------------------NSNYAVFFGGAGVSTASNIPDFRGKNGIYNTLPPEIIISHTFFTRRTKD---FYDYYKKYMV
YPSAVPNAVHIALARLEKEG-KIKAVLTQNIDGLHQAAGSKNVYELHGSVHRNYCTRCGKFYD-LDY--GVPTC-ECG--GVIKPDVVLYEEPLDVWQGA
WEEVRRADTLIVGGSSLTVYPAAGLVDM-FY-GKNLCIINATPTPFDR-RTYLSHDSLTREFENL--------------
>tr|H6LBZ5|H6LBZ5_ACEWD NAD-dependent protein deacetylase OS=Acetobacterium woodii (strain ATCC 29683 / DSM 1030 / JCM 2381 / KCTC 1655) GN=cobB PE=3 S
--------------------------------------NAGNIVFFGGAGVSTESGIPDFRSVDGLYNQYPPETILSHQFFVDNTEE---FYHFYRNKML
YLEAKPNAAHIKLAKLEAAG-KVKAVITQNIDGLHQMAGSKNVLELHGSVHRNYCVRCHQFYP-VQTI-GVPTCT-CG--GTIKPDVVLYGEGLDVMNQS
LSAITKAEVLIIGGTSLGVYPAAGLIDY-YR-GKQLVLINKTATPMDS-RNLAIKGSIGEVFKQI--------------
>tr|C4Z4Q8|C4Z4Q8_EUBE2 NAD-dependent protein deacetylase OS=Eubacterium eligens (strain ATCC 27750 / VPI C15-48) GN=cobB PE=3 SV=1
--------------------------------------ECDNIVFFGGAGVSTESGIPDFRSPDGLYNQYPPETIISHSFYQRYPEE---FYRFYKDKML
YPDAKPGITHLALAKLEKEG-KLKAVVTQNIDGLHQKAGSSNVIELHGSVLRNYCERCHKFYG-IDKI-GIPMCD-CG--GRIKPDVVLYEEGLDNVTNA
VNCIKQADMLIVGGTSLGVYPAAGLIDY-YR-GDKLVLINKSATPYDN-RDILINAPLADVFKNFM-------------
>tr|R0BP84|R0BP84_9FIRM NAD-dependent protein deacetylase OS=[Clostridium] bolteae 90A9 GN=cobB PE=3 SV=1
--------------------------------------GSDNIVFFGGAGVSTESGIPDFRSVDGLYNQYPPETIISHSFYMRYPEE---FYRFYKDRML
FTDAVPNQAHKALARLEERG-KLKAVITQNIDGLHQMAGSREVLELHGSVHRNYCTRCGQFYD-LDYVKGVPHCS-CG--GVIKPDVVLYEEGLDTLKKS
VDYIRHADILIIGGTSLVVYPAAGLIDY-YR-GNKLVLINKGATSRDS-QDLVISDPIGEVLGTVV-------------
>tr|A0A0J9BMQ3|A0A0J9BMQ3_9FIRM NAD-dependent protein deacetylase OS=[Clostridium] citroniae WAL-19142 GN=cobB PE=3 SV=1
--------------------------------------SSGNIVFFGGAGVSTESGIPDFRSVDGLYNQYPPETIISHSFYVRNPEE---FYRFYKDRML
FTHAKPNAAHQALARLEEQG-KLRAVITQNIDGLHQMAGSKEVLELHGSVHRNYCTRCGEFYG-LDHINGVPRCS-CG--GTVKPDVVLYEEGLDILQKS
VDYIRNADMLIIGGTSLVVYPAAGLIDY-YR-GNRLVLINKGATSRDS-QDLVISDSIGEVLGAVV-------------
>tr|R5YSR6|R5YSR6_9FIRM NAD-dependent protein deacetylase OS=Eubacterium sp. CAG:156 GN=cobB PE=3 SV=1
--------------------------------------ESDNIVFFGGAGVSTESGIPDFRSVDGLYNQFPPEEIISHSFYMKNKEE---FYRFYKDRML
YEGAQPNVTHKALAKLEQMG-KLKAIVTQNIDGLHQMAGSKVVYELHGSVMRNYCEKCGKFYD-FEYK-GVPHCE-CG--GDIKPDVVLYEEGLDIVEKA
IKAIEEADVLIIGGTSLIVYPAAGLIDY-YK-GDKLVLINKTMTIRDS-RDLVINDSLGKVFSEIM-------------
>tr|R5KQK0|R5KQK0_9FIRM NAD-dependent protein deacetylase OS=Eubacterium sp. CAG:161 GN=cobB PE=3 SV=1
--------------------------------------NSNNIVFFGGAGVSTESGVPDFRSVDGLYNQYPPETILSHTFFRTKTRE---FFEFYRDKML
FPDVKPNKAHYALAKLEKEG-KLKAVVTQNIDGLHQAAGSKVVYELHGSVHRNYCEKCGKFYD-FDYY-GIPECE-CG--GIIKPDVVLYEEGLNILNNS
VRAIANADVLIIGGTSLAVYPAAGLIDY-YK-GNKLVLINKSTTARDC-YDIVINQPIGEVLGQVV-------------
>tr|C0CTZ1|C0CTZ1_9FIRM NAD-dependent protein deacetylase OS=[Clostridium asparagiforme] DSM 15981 GN=cobB PE=3 SV=1
--------------------------------------ESHNIVFFGGAGVSTESGIPDFRSVDGLYNQYPPETIISHSFYVRYPEE---FYRFYKDRML
FADAKPNAAHRALAKLEADG-RLKAVITQNIDGLHQMAGSREVLELHGSVHRNYCTRCGKFYS-LDDIRGVPRCD-CG--GTVKPDVVLYEEGLDTLEKS
VRYIRQADMLIIGGTSLVVYPAAGLIDY-YR-GSKLVLINKDATARDS-QDLVINGRIGEVLGAVS-------------
>tr|U2D1Q5|U2D1Q5_CLOSY NAD-dependent protein deacetylase OS=[Clostridium] symbiosum ATCC 14940 GN=cobB PE=3 SV=1
--------------------------------------ESSNIVFFGGAGVSTESGIPDFRSTDGLYNQYPPETIISHSFYVKKPKE---FYRFYKNKML
FPEAKPNRAHMALAKLEREG-KVKAVVTQNIDGLHQAAGSREVLELHGSVHRNYCTRCGRFYS-LDDLKGVPVCD-CG--GVIKPDVVLYEEGLDVIQRS
VEYISRADVLIIGGTSLTVYPAAGLIDY-YR-GSKLVLINKSVTSRDG-QDLVICDSIGKVLGDAA-------------
>tr|R5U1A3|R5U1A3_9CLOT NAD-dependent protein deacetylase OS=Clostridium hathewayi CAG:224 GN=cobB PE=3 SV=1
--------------------------------------ESSRIVFFGGAGMSTESGIPDFRGVDGLYHQYPPETIISHSFYRQNPQE---FYRFYKNRML
FPEAEPNRAHLALAKLEAEG-KLKAVITQNIDGLHQAAGSKEVLELHGSVHRNYCTRCGKFYS-LEDLNGIPRCS-CG--GTIKPDVVLYEESLDVLSRS
VEYIIRADMLIVGGTSLTVYPAAGLIDY-YR-GNRMVLINKTVTPMDS-RDLVISGQLGEVLGEAA-------------
>tr|R5WKU5|R5WKU5_9FIRM NAD-dependent protein deacetylase OS=Coprococcus eutactus CAG:665 GN=cobB PE=3 SV=1
--------------------------------------ESDNIVFFGGAGVSTESGIPDFRSVDGLYNQYPPETIISHSFYLRNPEE---FYRFYKDKMI
FKDAKPNKAHLKLAELEREG-KLKAVITQNIDGLHQMAGSKNVIELHGSVHRNYCERCHAFYN-LDYV-GVPKCEKCG--GTVKPDVVLYEEALNNMSNA
LRYISEADTLIIGGTSLVVYPAAGLIRY-FR-GRKLVVINMSPTQSDA-NDLLIADKIGDVLGSL--------------
>tr|B7AX01|B7AX01_9FIRM NAD-dependent protein deacetylase OS=[Bacteroides] pectinophilus ATCC 43243 GN=cobB PE=3 SV=1
--------------------------------------DSDNVVFFGGAGVSTESGIPDFRGVDGLYNQYPPEEIISHSFYMRNPEE---FFRFYKDRML
YPEAEPSTTHIKLAELEQKG-ILKGVITQNIDGLHQKAGSRHVVELHGSVLRNYCEKCGRFYG-IDAL-GVPVCE-CG--GRIKPDVVLYEEGLNDISEA
VRLIEEADVLIVGGTSLGVYPAAGLIRY-YR-GHKLVLINKTPTPFDG-KDLLIHDSLGKVFGVL--------------
>tr|A0A078KQ83|A0A078KQ83_9FIRM NAD-dependent protein deacetylase OS=[Clostridium] cellulosi GN=cobB PE=3 SV=1
--------------------------------------ESKRIVAFTGAGVSTESNIPDFRSSKGVYESQPAERLLSHSYFEAHPEI---FFDYLRRFLV
FPDALPNDAHKSLAALERIG-KLSCVVTQNIDGLHTKAGNKNVCELHGSLYRNYCIKCGEKYD-LDF--DIPRCKKCG--GIVRPDVVLYEELLDVMEKA
ANEIINADMLLIMGTSLAVYPAAGFIRY-FR-GENIVIINRDATPYDG-SKLLIKAKAGETMRAVM-------------
>tr|R5AEK3|R5AEK3_9FIRM NAD-dependent protein deacetylase OS=Firmicutes bacterium CAG:102 GN=cobB PE=3 SV=1
--------------------------------------ESDNIVFFGGAGVSTESGIPDFRSENGIFHAVRPEVILSHTFFEQNPEV---FFKYYKKTLL
YPDAKPNDCHKALARLEEMG-KLKAVITQNIDDLHQKAGSKNVLELHGTLYRNYCVKCGKQFD-LDYTAGITRCDACG--GIVRPDVVLYEEGLDTIYKS
VDYISKADVLIVGGTSLNVYPAAGLLNY-YR-GNKLVLINKSATPYDN-KALVIAENIGEVFKKIV-------------
>tr|N1ZBG8|N1ZBG8_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. ASF356 GN=cobB PE=3 SV=1
--------------------------------------QSNRIVFFGGAGVSTESGIPDFRSENGIFMTFSPERILSHSFFLSNPEI---FFQYYKKNLL
YPDAKPNKAHKALAKLEKEG-KLRCVITQNIDDLHQRAGSKKVLELHGTLYQNYCTKCHKKFD-LEYTNGITKCDACG--GIVRPDVVLYEEGLDTIMEA
VDEIAKADMLIVGGTSLNVYPAAGLIRY-YN-GNKLVLINKSATQYDK-SDLIISDAIGNVLGTII-------------
>tr|F7KXL2|F7KXL2_FUSNU NAD-dependent protein deacetylase OS=Fusobacterium nucleatum subsp. animalis 11_3_2 GN=cobB PE=3 SV=1
----------------------------------------KYLVFFGGAGTSTDSGVKDFRGKNGLYKTYRPEEVLSSDFFYSHRDI---FMEYVEKELN
INGLKPNKGHMALVELEKMG-ILKAIITQNIDNLHQVSGSKNVLELHGSLKRWYCLGCGKTSD-KN------FSCECG--GIVRPDVTLYGESLNIVNEA
IYQLEQADTLIVAGTSLTVYPAAYYLRY-FR-GKNLIIINDMDTQYDG-ESLVIKDNFSYVMDKAV-------------
>tr|H3SG33|H3SG33_9BACL NAD-dependent deacetylase OS=Paenibacillus dendritiformis C454 GN=PDENDC454_12440 PE=4 SV=1
----------------------------------------RYTVFFGGAGTSTESGIPDFRSDRGLFSAYPPEMILSRSFFERDPVT---FYRYYRAKML
HPGAEPNGAHRTLAKLEEDG-IVKAVVTQNIDGLHQAAGSREVCELHGSVHRNRCMACGAEHD-LGIAEPIPHCPGCG--GMVKPDVVLYEEALDVINRA
VEHIRRADLLIVGGTSLNVMPAASFVRL-AA-GADIVIANRTPTSMDY-RAAVYREPMGALFEAAY-------------
>tr|S9U6P4|S9U6P4_PAEAL NAD-dependent protein deacetylase OS=Paenibacillus alvei TS-15 GN=cobB PE=3 SV=1
--------------------------------------SSRHVVFFGGAGTSTESGIPDFRSDNGVFADYPPEVMLSRSFYDRDPAT---FYRFYRAKML
HPSAKPNGAHRALARLEEDG-IVSAVVTQNIDGLHQAAGSKEVWELHGSVHRNRCTACGAEYG-LDALNVIPSCKQCG--GTLKPDVVLYEEQLNVISRA
IERIRESDLLIVGGTSLTVQPAASFVRL-AT-KAKLVLMNRTATSMDG-HDAVYREPMGELFTLAY-------------
>tr|J0NT05|J0NT05_9ACTO Transcriptional regulator, Sir2 family OS=Actinomyces georgiae F0490 GN=HMPREF1317_0415 PE=4 SV=1
----------------------------------------HDTVFFGGAGVSTESGIPDFRGATGFYHQIPLERVLSIDFFSACPDA---YYAWFAEETA
REGVAPNAAHRCLADLERAG-KLKAVVTQNIDGLHQAAGSKRVFELHGNWTRLECTGCGARST-IDDDERVPHCPSCS--AVVRPDIVFYGEALDTLEGA
VLAIAGADMLIVGGTSLAVYPAAGLIDY-YR-GGRLVLMNATPTPYDG-RDLIIREPIGRVFTQIQ-------------
>tr|D0WS10|D0WS10_9ACTO Transcriptional regulator, Sir2 family OS=Actinomyces sp. oral taxon 848 str. F0332 GN=HMPREF0972_02605 PE=4 SV=1
----------------------------------------NRIVFFGGAGVSTESGIPDFRGAEGFFHQIPIERVLSIDFFETHPQA---YWEWFAQENA
REGVAPNAAHRFLAELEKRG-SLSAVVTQNIDGLHQSAGSERIFELHGNWSRLLCMGCGRRFS-IADDEAVPRCPSCA--CVVRPDIVFYGEMLGVLEGA
VRAIADADMLIVAGTSLVVYPAAGLVDY-YD-GDRLVLMNATPTPYDS-RNLVIRDPVGKVFAELA-------------
>tr|F9PMU4|F9PMU4_9ACTO NAD-dependent protein deacetylase OS=Actinomyces sp. oral taxon 175 str. F0384 GN=cobB PE=3 SV=1
----------------------------------------SRIVFFGGAGVSTESGIPDFRGAKGFYHQIPLEQVLSIDFFTVHPQA---YWEWFAQEIA
REGVAPNAAHRLMADLERAG-KLSAVVTQNIDGLHQRAGSQRVLELHGNWSRLTCTGCGEHFT-LDDDGEVPHCPACS--SVLRPDIVFYGEMLDVMEGA
VRAISEADLLIVAGTSLVVYPAAGLIDY-YA-GERLVLMNATPTPYDS-RDLIIREPVGQVFQELE-------------
>tr|G9PIW3|G9PIW3_9ACTO NAD-dependent protein deacetylase OS=Actinomyces sp. oral taxon 849 str. F0330 GN=cobB PE=3 SV=1
----------------------------------------KRVVFFGGAGVSTESGIPDFRGAKGFYHQIPLEQVLSIDFFTVNPRA---YWEWFAQENA
REGVAPNAAHRFVADLERAG-RLSAVVTQNIDGLHQRAGSERVLELHGNWSRLICTGCGERFS-LSDDDAVPRCRECD--SVLRPDIVFYGEMLDVLEGA
VRAISEADLLIVAGTSLVVYPAAGLIDY-YA-GKRLVLMNATPTPYDS-RDLIVREPVGQVFQELE-------------
>tr|Z4X5R6|Z4X5R6_9ACTO Transcriptional regulator, Sir2 family OS=Actinomyces sp. ICM54 GN=HMPREF1522_0779 PE=4 SV=1
----------------------------------------PSTVFFGGAGVSTESGIPDFRGANGFYFQIPLETVLSIDFFERHPQA---YWEWFHEI--
YRPVAPNGAHRALASLEAAG-RLDAVITQNIDGLHQQAGSRAVWELHGNWERLVCTSCGAVAS-LGDVTPVPACPSCA--SQMRPDIVMYGEALDVIEAA
VSAIARASVLIVAGTSLVVYPAAGLINY-FS-GDHLVLMNATPTSADA-HDLIIREPVGATLDRVM-------------
>tr|A0A0K1N603|A0A0K1N603_9ACTO NAD-dependent deacetylase OS=Actinomyces meyeri GN=ADJ76_00790 PE=4 SV=1
----------------------------------------PSTVFFGGAGVSTESGIPDFRGANGFYFQIPLEQVLSIDFFARHPEA---YWQWFNEV--
HRPVEPNGAHAALASLEAAG-CVDAVVTQNIDGLHQKAGSHAVWELHGNWERLVCTGCGDVLP-LGEVRPVPACPSCG--AQMRPDIVMYGEALDVIEGA
VAAISRASLLIVAGTSLVVYPAAGLINY-FS-GDHLVLMNATPTSADA-HDLIIRDPVARIFDRVM-------------
>tr|S2ZNX0|S2ZNX0_9ACTN NAD-dependent deacetylase OS=Atopobium sp. oral taxon 199 str. F0494 GN=HMPREF1527_00810 PE=4 SV=1
----------------------------------------SHLVFFGGAGVSTESGIPDFRGKDGLYSRITLEEIFSLDIFEDFPEA---YYTYFRNSHH
LGEAKPNVTHRKLAQWEREG-KLKAVITQNIDGLHQAAGSENVFELHGNETRFYCSDCGHAYT-LDEEAMVPLC-ACG--GTIRPDIVFYGEGLNVFYRA
LAALAAADVLIVAGSSLVVYPAAGLLDY-YT-GHKMVIINDMPTPYDG-RDLVIHSRIGEVFSQL--------------
>tr|Z4WW78|Z4WW78_9ACTN Transcriptional regulator, Sir2 family OS=Atopobium sp. BS2 GN=HMPREF1492_1459 PE=4 SV=1
----------------------------------------DNIVFFGGAGVSTESGIPDFRGTNGLYRQFTLEEIFSLDVFFDYPAA---YYTYFRNSHH
LGEAQPNIAHKWLADLEAAG-KLRAVVTQNIDGLHQAAGSKRVFELHGNETRFYCPECGHTYT-LDQEEVVPLC-QCG--AVIRPDIVFYGEGLDTVYGA
LNAISQAEVLVVAGSSLVVQPAAGLLDY-YE-GNKMVIINDQPTPYDG-RNLVIRDRIGAVIEQLL-------------
>tr|A0A0R2LS92|A0A0R2LS92_9ACTN NAD-dependent deacetylase OS=Atopobium rimae GN=IV60_GL000927 PE=4 SV=1
----------------------------------------SHLVFFGGAGVSTESGIPDFRGKNGLYRQFTLEEIFSRDVFDDTPEA---YYTYFRNSHH
LGEAKPNITHRKLAEWERAG-KLLAIITQNIDGLHQAAGSKKVFELHGNEIRFYCSDCRHAYT-LDEEALVPLC-SCG--GVIRPDIVFYGEGLNVFYGA
LEAIAAADVLIVAGSSLVVYPAAGLLDY-YT-GERMVIINDMPTPYDR-RNLVIRRKIGEVFSQL--------------
>tr|R5QP22|R5QP22_9FIRM NAD-dependent protein deacetylase OS=Firmicutes bacterium CAG:194 GN=cobB PE=3 SV=1
--------------------------------------ESEKIVFFGGAGVSTESGIPDFRSVDGLYHQYPPETILSHTFFMRKPEE---FYRFYRDKML
CLSAKPNAAHKKLAELEKAG-KLTAVITQNIDGLHQAAGSRKVYELHGSVLRNYCQKCGKFYT-AEYL-GVPKCE-CG--GVIKPDVVLYEEGLDTIEKS
VQAIREADMLIIGGTSLVVYPAAGLIDY-YN-GNKLVLINKSETSRDS-LDLIITDSIGEVLSGIQ-------------
>tr|A0A0M2NCF7|A0A0M2NCF7_9FIRM NAD-dependent protein deacetylase OS=Catabacter hongkongensis GN=cobB PE=3 SV=1
--------------------------------------DSNRIVFFGGAGVSTESGIPDFRSVDGLYHQYPPETILSHDFFMANTKE---FFEFYRDKML
LPEAKPNSAHKKLASWEREG-KLSAVVTQNIDGLHQAAGSKHVLELHGSVHRNYCMDCGKFYG-TEYL-GIVRC-SCG--GVVKPDVVLYGESLRVLEES
VSCIASADMLIVGGTSLAVYPAAGLVDY-YM-GAKLVLVNKSATPFDH-RDLLVTDKIGDVFSKL--------------
>tr|R6H9I3|R6H9I3_9FIRM NAD-dependent protein deacetylase OS=Firmicutes bacterium CAG:137 GN=cobB PE=3 SV=1
--------------------------------------ESHRIVFFGGAGVSTESGIPDFRSVDGLYHQYPPETIISHSFYRANPAY---FFRFYREKML
PLGFQPNVTHQKLAQWEQEG-KLLAVVTQNIDGLHQKAGSRRVYELHGSVLRNYCEKCGKFYP-AEYK-GVPLC-TCG--GTVKPDVVLYEESLDTLTGS
ICAIGQADLLMVGGTSLTVYPAAGLIQY-YR-GNRLVLINRDETPYDG-YNLVLHRSLGEVFSQL--------------
>tr|A0A0A7LAP5|A0A0A7LAP5_9EURY NAD-dependent protein deacetylase OS=Candidatus Methanoplasma termitum GN=cobB1 PE=3 SV=1
--------------------------------------GSDNIVFFGGAGVSTESGIPDFRSTSGLYNQYPPEEIISHSFFMRDPEE---FYRFYRNKMV
CLDAKPNAAHFKLAELESKG-KLRAVVTQNIDNLHQLAGSKCVHELHGSVFRNYCTRCGKFYT-AEYMQGIPRCD-CG--GTIKPDVVLYEEVLDVLRKS
IQAIQEADVLIIGGTSLVVYPAAGLLQY-YL-GNKLILINKTELPQES-RALVIHGKIGEIMSQI--------------
>tr|R7N6F3|R7N6F3_9FIRM NAD-dependent protein deacetylase OS=Firmicutes bacterium CAG:95 GN=cobB PE=3 SV=1
--------------------------------------NSNNIVFFGGAGVSTESGIPDFRSVDGLYHQYPPETILSHTFYRQKPEE---FFRFYKDKML
CLTAEPNAAHRKLAEWEQQG-KLKAVITQNIDGLHQKAGSKKVLELHGSVLRNYCETCGKFFD-AEYL-GIPKCDACG--GRVKPDVVLYEEGLNTLQEA
VHYIKEADVLIVGGTSLVVYPAAGLIDY-YQ-GNKLILINKTATARDG-IDLVVQGAIGEIFSQL--------------
>tr|R5IU45|R5IU45_9FIRM NAD-dependent protein deacetylase OS=Firmicutes bacterium CAG:124 GN=cobB PE=3 SV=1
--------------------------------------ESDNIVFFGGAGVSTESGIPDFRSTDGLYHQYPPETILSHTFFYQNPEY---FFRFYREKML
PLDYQPNEAHKKLAALEQAG-KLRAIVTQNIDGLHQKAGSKNVFELHGSIYRNYCEKCGKFYP-PEYR-GIPRCT-CG--GRIKPDVVLYEESLDVIEGA
VRAIADAEVLIVGGTSLTVYPAAGLIRY-YR-GNKLVLINRDETPYDG-YNLIFRDPIGKVLGAI--------------
>tr|R7A3J6|R7A3J6_9FIRM NAD-dependent protein deacetylase OS=Firmicutes bacterium CAG:534 GN=cobB PE=3 SV=1
--------------------------------------GSNNIVFFGGAGVSTESGIPDFRSVDGLYHQYPPETILSHTFYKRKPEE---FFRFYKDKML
CLWAKPNAAHQKLAQWEKEG-KLKAVITQNIDGLHQAAGSRKVLELHGSVLRNYCEGCGKFFD-AEYL-GVPRCDACG--GTIKPDVVLYEEGLDILTEA
IHYIGQADVLIIGGTSLVVYPAAGLIDY-YK-GKKLVLINKTPTARDN-VDLVVQGSIGEIFSAL--------------
>tr|R7HAJ5|R7HAJ5_9FIRM NAD-dependent protein deacetylase OS=Eubacterium sp. CAG:38 GN=cobB PE=3 SV=1
--------------------------------------ESDNIVFFGGAGVSTESGIPDFRSVDGLYHQYPPETILSHSFYMRKPEE---FFRFYKNKML
FPKAEPSTTHKKLAKLEADG-KLKGIVTQNIDGLHQKAGSRHVIELHGSVLRNYCERCHQFYG-LDAL-GVPKCS-CG--GRIKPDVVLYEEGLDNIEEA
VRLIREADLLIVGGTSLGVYPAAGLIDY-YR-GHKLVLINKSETPYDN-RDLLIHDALGEVFSKIG-------------
>tr|R5H2B8|R5H2B8_9FIRM NAD-dependent protein deacetylase OS=Firmicutes bacterium CAG:24 GN=cobB PE=3 SV=1
--------------------------------------QSDNIVFFGGAGVSTESGIPDFRSTDGLYHQYPPETILSHTFFRQNPEE---FYRFYRAKML
APHAKPNAAHKKLAQWEKEG-KLKAVITQNIDGLHQAAGSKTVLELHGSTLRNYCMKCGRFYD-QNAL-GVPHCE-CG--GVIKPDVVLYEESLDVLKEA
VSFISHADVLIVGGTSLVVYPAAGLIDY-YR-SDKLVLINRTPTARDS-ADLVVTGSIGEIFDSL--------------
>tr|R9J3Y1|R9J3Y1_9FIRM NAD-dependent protein deacetylase OS=Lachnospiraceae bacterium 28-4 GN=cobB PE=3 SV=1
--------------------------------------ESDNIVFFGGAGVSTESGIPDFRSVDGLYHQYPPETILSHTFYRNKPEE---FYRFYRDKLI
GFEAEPNQAHKKLAQWEQDG-KLKAVITQNIDGLHQAAGSRKVLELHGSTLRNYCEHCGKFFD-VEDR-GVPVCDACG--GPVKPDVVLYEEGLDVLSEA
VQFIKNADVLIIGGTSLVVYPAAGLIDY-YR-GNKLVLVNKTPTARDG-VDLVVQGAIGEIFGQL--------------
>tr|A0A017H5X6|A0A017H5X6_9FUSO NAD-dependent deacetylase OS=Fusobacterium necrophorum subsp. funduliforme B35 GN=C095_09630 PE=4 SV=1
----------------------------------------THLVFFGGAGTSTDSGIKDFRGKNGLYQEYAPEEVLSIDFFRTHHDL---FLKYVEEKLA
IHNIKPHAGHYALVELENMG-KLKSIITQNIDNLHQEAGSKKVLELHGTLKDWYCLSCNKHDT-HN------FSCACG--GIVRPNVTLYGEMLNVTEEA
VQEIRKADVIIVAGSSLTVYPAAYYLQY-YR-GNQLVIINQSPTQYDK-QGLLIPENFARTMTKVL-------------
>tr|E5BGG1|E5BGG1_9FUSO Putative NAD+ dependent deacetylase OS=Fusobacterium gonidiaformans 3-1-5R GN=FSBG_01081 PE=4 SV=1
----------------------------------------KHLVFFGGAGTSTDSGIKDFRGKNGLYQEYSPEEVLSIDFFHRHRDL---FLKYVEEKLS
IANIKPHAGHYALVELEKMG-KLKTIITQNIDDLHQAAGSKKVLELHGTLKDWYCLSCEKHNT-HP------FQCQCG--GTVRPNVTLYGEMLNVTEAA
IREIQKADVLIIAGSSLTVYPAAYYLQY-YK-GNKLVIINQSPTQYDK-QGLLISKNFAETMTEVL-------------
>tr|U2QNF5|U2QNF5_9FIRM NAD-dependent protein deacetylase OS=Oscillibacter sp. KLE 1745 GN=cobB PE=3 SV=1
--------------------------------------SSDNIVFFGGAGVSTESGIPDFRSTGGLYHQYPPEVILSHTFYESNPEE---FFRFYRAKLL
APDAKPNAAHKKLAEWEAEG-RLKAVITQNIDGLHQAAGSRNVLELHGSVHRNHCQRCGKFYG-LEHL-GVPRCS-CG--GIIKPDVVLYEEGLDTLEAA
VRALAEADMLMIGGTSLNVYPAAGLIRY-YQ-GHRLVLLNKSPVARDL-ADLVITDPIGETLAQL--------------
>tr|B0PC38|B0PC38_9FIRM NAD-dependent protein deacetylase OS=Anaerotruncus colihominis DSM 17241 GN=cobB PE=3 SV=1
--------------------------------------ESRRIVFFGGAGVSTESGIPDFRSADGLYRQYPPETIVSHTFFMERPEE---FFAFYREKML
APDARPNAAHKALAHLESEG-KLTAVVTQNIDGLHQAAGSKNVLELHGSVHRNHCMRCGKFYD-LHAL-GVPVCS-CG--GTIKPDVVLYEEQLDVLMGA
VEALSQADLLIVGGTSLAVYPAAGLVRY-CK-GR-LAVINMSPTPLDA-GDLLIQAPIGETLKDF--------------
>tr|G9RQJ1|G9RQJ1_9FIRM NAD-dependent protein deacetylase OS=Subdoligranulum sp. 4_3_54A2FAA GN=cobB PE=3 SV=1
--------------------------------------ASEAIVFFGGAGVSCESGIPDFRSTDGLYHQWPPEEILSHDFFERRPEE---FFRFYRDKML
YPQAEPNAAHLALARLEQAG-KLKAVVTQNIDGLHQAAGSKNVLELHGSVHRNHCTRCGAFYT-LDDL-GVPRCG-CG--GVIKPDVVLYGEALDTLNAA
VRAIRRADLLLVGGTSLNVYPAAGLLRY-FT-GAALAVVNKTPTPADA-RDLVIQASIGRVLGGFE-------------
>tr|D1AK96|D1AK96_SEBTE NAD-dependent protein deacetylase OS=Sebaldella termitidis (strain ATCC 33386 / NCTC 11300) GN=cobB PE=3 SV=1
--------------------------------------NSNNIVFFGGAGVSTESGIPDFRSADGLYQ-NNPETILSHSFFLKNPEI---FFEFYKKNLI
FTEAKPNAAHNILAKMEKDK-KLKGIITQNIDALHQKAGSSNVFELHGSISRNFCMKCRKYYS-LDDLDLVPLC-SCG--GIIKPDVVLYEEELDVINGA
VKLLKNADVLIVGGTSLMVNPAASLINY-FS-GSCLALINISSTPYDS-QDIIIREKIGETFTEIY-------------
>tr|R6UU11|R6UU11_9FIRM NAD-dependent protein deacetylase OS=Oscillibacter sp. CAG:155 GN=cobB PE=3 SV=1
--------------------------------------SSRSMVFFGGAGVSTESGIPDFRSTDGLYHQYPPEVILSHTFYESNPAE---FFRFYRAKLL
APDAKPNAAHRKLAQWEQEG-KLAAVITQNIDGLHQAAGSKHVLELHGSVHRNYCEKCGKFYD-LDYL-GIPRCS-CG--GTIKPDVVLYEESLNTLNES
IRLISEADLLIIGGTSLNVWPAAGLINY-YR-GRHLVLINKSPVARDL-SDLVITDPIAATLDQL--------------
>tr|R5CTF7|R5CTF7_9FIRM NAD-dependent protein deacetylase OS=Firmicutes bacterium CAG:555 GN=cobB PE=3 SV=1
--------------------------------------ESDNVVFFGGAGVSTESGIPDFRSVDGLYNQYPPETILSHTFFTRYPEE---YYKFHREKLV
VDGVKPNAAHLKLAELERQG-KLRAVVTQNIDGLHQAAGSKNVLELHGSILRSYCSACHRPYP-ADKN-GVPRC-ICG--GVIRPDIVLYEEPLDVVSEA
IKCISEAEVLIIGGTSLNVYPAAGLINY-YR-GNKLALVNLSSTPYDS-EDLVIHEKIGKVFSQI--------------
>tr|R5B5K6|R5B5K6_9FIRM NAD-dependent protein deacetylase OS=Firmicutes bacterium CAG:103 GN=cobB PE=3 SV=1
--------------------------------------GSDRIVFFGGAGVSTESGIPDFRSVDGLYNQYPPETILSHSFFMAHPEE---YYKFHRDKLV
VDGAKPNRAHLRLAELEREG-KLQAVITQNIDGLHQAAGSKNVLELHGSIHRCYCMRCGRPYP-AERN-GVPHC-DCG--GIIRPDIVFYEECLDVVSKA
VHYIREAEVLIVGGTSLAVYPAAGLLNY-YR-GSKLVLINRSATPYDD-QNLIIHEKIGEVFAQV--------------
>tr|R5RXH5|R5RXH5_9FIRM NAD-dependent protein deacetylase OS=Firmicutes bacterium CAG:129 GN=cobB PE=3 SV=1
--------------------------------------GSDNIVFFGGAGVSTESGIPDFRSVDGLYRQDPPETILSHTYYERYPEK---FFAFYRAKLL
CPDTKPNAAHRKLAEWERAG-KLKAVITQNIDGLHQAAGSKEVLELHGSTLRNYCERCGKFYG-VEAT-GVPTCS-CG--GRIKPDVVLYEEGLNTLYKA
VRYIAEADVLIIAGTSLAVYPAAGLVNY-YR-GHKLVVINKTPLSDKT-RDLVITGAVGETLAQV--------------
>tr|R6SXP1|R6SXP1_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. CAG:448 GN=cobB PE=3 SV=1
--------------------------------------RSSRIVFFGGAGVSTESGVPDFRSTDGLYHQYPPETILSHSFFMAHTEE---FYDFYREKLL
IENALPNPAHRKLAELERAG-KMTGVVTQNIDGLHTLAGSERVFELHGSVHRNYCMRCGRFYP-RAYA-GVPRC-SCG--GIVKPDVVLYEEPLNVVAGA
VDAIRRADLMIIGGTSLAVYPAAGLIRC-FG-GQDLVLINRDPTGADD-ESLIIREPIGQVLGSMR-------------
>tr|A9NEY3|A9NEY3_ACHLI Uncharacterized protein OS=Acholeplasma laidlawii (strain PG-8A) GN=ACL_0289 PE=4 SV=1
----------------------------------------NYIVFFGGAGVSTESGIKDFRSKDGLYSQYRPEDILSRSFFFNHTKD---FYEYFRRHFL
DTGIKPNKAHMWLKDAESIG-KVKCVITQNIDGLHQMAGSKNVVELHGSAHRYYTVKKKQPID-GLTILDIPVDS-EG--DLIKPDVVLYEEPLNVVRKA
IEEISKADTLIVAGTSLTVYPAASFIEY-FK-GKHLIVINKEYMQFK----HFIEGQVGEILSQIK-------------
>tr|R6LQ91|R6LQ91_9FIRM NAD-dependent protein deacetylase OS=Coprococcus comes CAG:19 GN=cobB PE=3 SV=1
--------------------------------------ESNRIVFFGGAGVSTESNIPDFRSADGLYKQYSPEQIVSHSFFMQHTEE---FYDFYKEKMM
FLDAKPNKAHLKLAELEAAG-KLTAVITQNIDGLHQAAGSKNVLELHGSIHRNYCMRCKKQYS-ARFKEGIPTCD-CG--GTIRPDVVLYEEGLDIIQKS
IRAISEADMLIIGGTSLVVYPAAGFIDY-FH-GKYLVLINKDATARDV-GTLTIHEPIGEVLDRIH-------------
>tr|F3BBC1|F3BBC1_9FIRM NAD-dependent protein deacetylase OS=Lachnospiraceae bacterium 2_1_46FAA GN=cobB PE=3 SV=1
--------------------------------------DSHRIVFFGGAGVSTESNIPDFRSSDGIYQEYPPEQVVSHTFFQKKPEL---FYEFYKEKMM
FLDAKPNKAHLKLAEMEEKG-KLSAIITQNIDGLHQLAGSKNVLELHGSIHRNYCQRCGKFYG-AKYKEGIPICE-CG--GTIKPDVVLYEESLDVIQKS
VREIAQADMLIIGGTSLVVYPAAGFIDY-FR-GKHLVVINKSATPRDE-QDLCIQKPIGEVLEGIT-------------
>tr|R6H163|R6H163_9FIRM NAD-dependent protein deacetylase OS=Oscillibacter sp. CAG:241 GN=cobB PE=3 SV=1
--------------------------------------ESESIVFFGGAGVSTESGIPDFRSVDGLYHQYPPETILSHSFYVRRKAE---FYDFYRAKML
APWAEPNAAHRKLAQWEQEG-RLKAVITQNIDGLHQKAGSREVLELHGSVLRNYCERCGAFYG-LDTL-GVPRCPACG--GDIKPDVVLYEESLDVLAKA
VHYIRQADLMIIGGTSLVVYPAAGLVQY-FR-GRHLVVVNKGQVGSNV-GDLTIDGPIGQVFSQL--------------
>tr|R6DT57|R6DT57_9FIRM NAD-dependent protein deacetylase OS=Firmicutes bacterium CAG:176 GN=cobB PE=3 SV=1
--------------------------------------ASDNIVFFGGAGVSTESGIPDFRSVDGLYHQYPPETMLSHTFYETHTEE---FYDFYRAKML
ALDAQPNAAHRKLAEWERQG-KLKAVITQNIDGLHQKAGSQEVLELHGSVLRNHCTRCGKFYG-VERA-GIPRCT-CG--GIIKPDVVLYEESLDVMARA
IHYIRQADVLIIGGTSLVVYPAAGLIQY-YR-GHKLAVINKGGAGSGL-GAVTIDGPIGQVMAQL--------------
>tr|R5D3L5|R5D3L5_9FIRM NAD-dependent protein deacetylase OS=Firmicutes bacterium CAG:83 GN=cobB PE=3 SV=1
--------------------------------------SSDNIVFFGGAGVSTESGIPDFRSVDGLYHQYPPETILSHTFYERHKEE---FFDFYRQKLI
APEARPNAAHVKLAQWERDG-KLKAVITQNIDGLHQMAGSHEVLELHGSVLRNYCERCGKFYG-VDAL-GVPKCS-CG--GDIKPDVVLYEESLDMMEQA
LEYISRADMLIIGGTSLVVYPAAGLVQY-YR-GHKLVVINKGEVGAGV-RDLTIRAPIGEVLSQL--------------
>tr|R5VK83|R5VK83_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. CAG:167 GN=cobB PE=3 SV=1
--------------------------------------ESNNIVFFGGAGVSTESNIPDFRSVDGLYHQYPPETILSHSFYQRNTEE---FYKFYWNKMI
FPDAEPNKAHLALAALEQQG-KLKAVITQNIDGLHQKAGSKEVLELHGSVLRNYCTRCGKFYS-LEDV-GVPKCE-CG--GTIKPDVVLYEEGLDTLNKA
VHYIQQADMLIIGGTSLAVYPAAGLIDY-YS-GHKLVLINRDETPRDN-IDLVLHESIGQVLAPFT-------------
>tr|R5EMZ2|R5EMZ2_9FIRM NAD-dependent protein deacetylase OS=Firmicutes bacterium CAG:110 GN=cobB PE=3 SV=1
--------------------------------------ESNRIVFFGGAGVSTESGIPDFRSVDGLYHQYPPEVIISHSFYERNPEY---FFRFYREKML
PLGFEPNITHRILAKWEQEG-KLLAVVTQNIDGLHQKAGSKKVYELHGSVLRNYCTRCGKFYS-AEFK-GIPRC-SCG--GIVKPDVVLYEESLDTIAGS
VKAIRSADMLIVAGTSLTVYPAAGLINY-YR-GSRLVLINRDETPYDD-RDLVLHESLGDVFSQFA-------------
>tr|R7C8C3|R7C8C3_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. CAG:62 GN=cobB PE=3 SV=1
--------------------------------------ESDNIVFFGGAGVSTESKIPDFRSVDGLYKQYPPETILSHSFYIRNPEE---FYRFYRDKML
FPDADPNAAHIALANLEKQG-KLKAVITQNIDGLHQKAGSKEVLELHGSVLRNHCTHCHKFYS-LEDLAGVPHCE-CG--GIIKPDVVLYEEGLDLMERA
ISYIRDADLLIIGGTSLVVYPAAGLIDY-YQ-GDKLVLINKDKTSKDN-RNLILHEPIGEVLKPLA-------------
>tr|R7A1G4|R7A1G4_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. CAG:43 GN=cobB PE=3 SV=1
--------------------------------------ESNYIVFFGGAGVSTESNIPDFRSTDGLYHQYPPETILSHSFYMRKPEE---FYRFYRNKML
FPNAKPNRAHLALAKLEQEG-KLKAVITQNIDGLHQAAGSKEVLELHGSVLRNHCTRCGRFYG-LDDLKGVPKCG-CG--GVIKPDVVLYEEGLDVIERS
IAHIRKADMLIIGGTSLVVYPAAGLIDY-YH-GNKLVLINKSATSHDG-QDLVISDSIGKVLGDAV-------------
>tr|S7J2Q9|S7J2Q9_9FIRM NAD-dependent protein deacetylase OS=Megasphaera sp. NM10 GN=cobB PE=3 SV=1
--------------------------------------NSDNIVFFGGAGVSTESGIPDFRSTDGLYNQYPPETILSHSFFMDNTEE---FYRFYRDKML
ALDAQPNMAHIKLAELEKAG-KLKAIVTQNIDGLHQKAGSKNVLELHGSVHRNFCMHCNKFFD-AEYKNGIPKCDACG--GTIKPDVVLYEEGLDVIEQS
LYYISHADMLIIGGTSLVVYPAAGLVRY-YR-GHKLVLINKSSTDMDS-ADLVLHDPIGEVFSHVK-------------
>tr|G9YKE8|G9YKE8_9FIRM NAD-dependent protein deacetylase OS=Anaeroglobus geminatus F0357 GN=cobB PE=3 SV=1
--------------------------------------ESNNIVFFGGAGVSTESGIPDFRSVDGLYNQFRPETILSHTFYVNNKDE---FYRFYRDKML
CLDAAPNAAHLKLAELERAG-KLKAVITQNIDGLHQKAGSKNVLELHGSVHRNYCEQCRKFFD-AAYK-GIPVCDACG--GPIKPDVVLYEESLDVIAAT
VRYIREADMLIIGGTSLVVYPAAGLVHY-YQ-GRKLVLINKGATDMDG-TDLVLHEPIGEVFRNIT-------------
>tr|H1PIK6|H1PIK6_9FIRM NAD-dependent protein deacetylase OS=Eubacterium infirmum F0142 GN=cobB PE=3 SV=1
--------------------------------------KSNKIVFFGGAGVSTESNIPDFRSESGIYHAYPPESIVSADFYFNHNKL---FYKFYKENLV
YMEAEPNDAHKALSKLEQEG-KLTAVVTQNIDGLHQKAGSRNVYELHGSVNRNYCEKCGKFYD-LEYMDGVPYCS-CN--GRIKPDVVLFGEMLDTIEGA
VKAISEADLLIVGGTSLAVYPAAGLINY-YR-GKELVLINKTETPYDS-RSLVIYDSIGKVMKY---------------
>tr|G5IMQ3|G5IMQ3_9CLOT NAD-dependent protein deacetylase OS=Hungatella hathewayi WAL-18680 GN=cobB PE=3 SV=1
--------------------------------------GSDNIVFFGGAGVSTESGIPDFRSEDGLYRQYPPETIISHSFYMKNPEE---FYRFYKNKMI
FEDAKPNPAHLALARLEKQG-KLKAVITQNIDGLHQAAGSREVLELHGSIHRNYCTRCGKFYG-LDVTKGVPKCS-CG--GMVKPDVVLYEEGLDTLQKA
VYYISHADMLIVGGTSLTVYPAAGLIDY-YR-GRKLVLINKTVTPMDS-QDLVINDKLGEVLGSVV-------------
>tr|A0A0L6U410|A0A0L6U410_9FIRM NAD-dependent protein deacetylase OS=Acetobacterium bakii GN=cobB PE=3 SV=1
--------------------------------------NSENIVFFGGAGVSTESGIPDFRSVDGLYSQYPPETILSHRFFMENTEE---FYDFYRNKML
FLEAKPNKAHKKLAELENIG-KLKAVITQNIDGLHQLAGSKNVLELHGSVHRNYCLKCHQYYG-VTAV-PIPKCT-CG--GMLKPDVVLYGEGLDTVEQS
VKAIAGADMLIIGGTSLGVYPAAGLIDY-YR-GNKLVLINKTSTPMDK-QDLVINDSIGEVLGGLE-------------
>tr|R7G5L0|R7G5L0_9FIRM NAD-dependent protein deacetylase OS=Eubacterium dolichum CAG:375 GN=cobB PE=3 SV=1
--------------------------------------ASKTIVFFGGAGVSTESNIPDFRSADGIYEKYPAEYMLSSDFFYANTEA---FYDFYFHEML
YPNALPNPAHTALVRLEKQG-KLQSVITQNIDGLHQLAGSKEVVELHGSVHRNYCLKCHTFYS-LEDLKKVPRCPKCG--GIIKPDVVLYGEGLKMIHKA
IYDIAHADTLIVGGTSLAVYPAAGLLQY-FR-GKHLVLINRDATAMDL-RELVIHDPIGKVLDCVV-------------
>tr|R6EPY8|R6EPY8_9FIRM NAD-dependent protein deacetylase OS=Firmicutes bacterium CAG:145 GN=cobB PE=3 SV=1
--------------------------------------DSKSIVFFGGAGVSTESGIPDFRSEKGLYSAFSPEEILSHTFFMRHMEV---FFDYYKKNLI
YMDAQPGDAHRTLAHLEREG-KLKAVVTQNIDGLHQKAGSRNVFELHGSVLRNYCMDCGEYHD-VEYMNGIPLCRKCG--GVVKPDVVLYEEVLDCVNGA
ISAISAADTLIIGGTSLVVYPAAGLIRY-FR-GNNLVLINKQATGYDS-KNLVINDQIGKVMKI---------------
>tr|G9XAL2|G9XAL2_9FIRM NAD-dependent protein deacetylase OS=Peptostreptococcaceae bacterium CM5 GN=cobB PE=3 SV=1
--------------------------------------NSDNIVFFGGAGVSTESDIPDFRSSNGIFNAYSPETVVSHSFFMRNPEF---FYQFYKDKMI
YENAKPNNAHKALAKLEQIG-KLKAIITQNIDGLHQMAGSKNVLELHGTIHKNYCMKCNKNFD-LDYIKNIPHCDVCG--GTVRPDVVLYEESLDVLSES
LHYISNADVLIIGGTSLIVYPAASLVNY-FR-GSKLVLINKSSTSQDG-NDIVINDSIGKVLGDIV-------------
>tr|J5GNS9|J5GNS9_9FIRM NAD-dependent protein deacetylase OS=Peptostreptococcaceae bacterium AS15 GN=cobB PE=3 SV=1
--------------------------------------NSDNIVFFGGAGVSTESNIPDFRSSKGIFNEYSPETVVSHNFFMSNPEF---FYEFYKSKMV
YPEAKPNKAHIALANLEKAG-KLKAVITQNIDGLHQMAGSKNVLELHGTIHKNTCTKCAKKFE-LDYIKNIPKCDACG--GTIKPDVVLYGESLDVIEKS
IYFISNADVLIIGGTSLVVYPAAGFIRY-FK-GSKLVLINKSETAYDR-DDIVIHDSIGQVMDYCQ-------------
>tr|R5R3X3|R5R3X3_9FIRM NAD-dependent protein deacetylase OS=Firmicutes bacterium CAG:646 GN=cobB PE=3 SV=1
--------------------------------------RYDRIVFFGGAGVSTESGIPDFRSADGLYHQYPPETILSHTFFMRHPEE---FYRFYRDKML
ALDARPNAAHRKLAQLEQAG-KLTGVVTQNIDGLHQMAGSKHVMELHGSVHRNYCMKCHDHYS-ARDL-GIPRCA-CG--GMIKPDVVLYEEGLDTIRDA
IRTIARAQMIIVGGTSLAVYPAAGLLDY-FQ-GEALVLINKGATPQDK-NDLLIQKPIGQVLDQIH-------------
>tr|D2MNH3|D2MNH3_9FIRM Transcriptional regulator, Sir2 family OS=Bulleidia extructa W1219 GN=HMPREF9013_0198 PE=4 SV=1
----------------------------------------HKIVFFTGAGVSTASGIPDFRSQDGLYHQDPPEKILSHSYFMEHTAE---FFEFYRDKML
YLNVRDSYVHQFIAQLEKEG-KSVNVITQNIDGLHQKAGSGHVLELHGSVLRNYCMNCHQARS-AQFKEGIPKCSICG--GIIKPDVVLYEEGLDILYQA
IRVLDEADVCVIMGTSLVVYPAAGLLRY-FH-GDTLVLINREITPYDD-QDLVLHMDFKEIFQK---------------
>tr|R6RGD8|R6RGD8_9FIRM NAD-dependent protein deacetylase OS=Firmicutes bacterium CAG:449 GN=cobB PE=3 SV=1
--------------------------------------ESTSIVFFGGAGVSTESGIKDFRSQDGLYNEYPPEEILSHDFFFSHPKE---FYEFYFSKMI
NENISPNIAHYKLAELEKKH-KLKAIITQNIDGLHQKAGSKIVYELHGTVYKNRCCKCHKFYS-LDDLKPVPYC-SCG--GLIKPEVVLYQEPLDTLIKA
IEAIENCSTLIIAGTSLSVYPAASLIDF-FK-GKNLVLINKTSTPKDN-ITLVIHQKVGEVLSKIN-------------
>tr|A0A0K8J2A1|A0A0K8J2A1_9FIRM NAD-dependent protein deacetylase OS=Herbinix sp. SD1D GN=cobB PE=3 SV=1
--------------------------------------ESDNIVFFGGAGVSTESGIPDFRSVDGLYHMYPPETILSHSFFIRHTEQ---FYEFYKEKMI
YKDVKPNITHLKLADLEKQG-KLKAVVTQNIDGLHQEAGSKNVLELHGSVLRNFCMNCNKFYD-LNKIKNIPYCQ-CG--GIIKPDVVLYEESLDTITKA
IQFISKADILIIGGTSLSVYPAAGLIRY-YK-GRKMVLINKSVTAYDN-DDLFIQAGLGEVFKEL--------------
>tr|R6PXR5|R6PXR5_9FIRM NAD-dependent protein deacetylase OS=Faecalibacterium sp. CAG:82 GN=cobB PE=3 SV=1
--------------------------------------ESGNIVFFGGAGVSTESGIPDFRSVDGLYHQYPPEEILSHTFWEENPEE---FYRFYRDKLI
VKGAKPNAAHLRLARLEKEG-KLKAVITQNIDGLHQAAGSQNVFELHGSTLRNYCTGCGAFYD-VDFA-GVPRCPKCG--GIIKPDVVLYEEGLDVLSGA
VQAIRKADTLIIGGTSLVVYPAAGLIRY-FR-GRHLVVINMQPTGADA-QDLCIAKPIGQVLREDI-------------
>tr|R5RY92|R5RY92_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. CAG:122 GN=cobB PE=3 SV=1
--------------------------------------ESSHIVFFGGAGVSTESGIPDFRSVDGLYHQYPPETILSHSFFIRNPKE---FYKFYRDKML
IENAKPNITHLKLAELEKSG-KLSAIVTQNIDGLHQAAGSKTVYELHGSTLRNYCEKCHKFYD-VNYKNGVPLCD-CG--GIIKPDVVLYEEGLDTISNS
IKAIANADMLIVGGTSLAVYPAAGLLQY-YT-GNRLVLINKSSTPLDN-NDLLLQCGLGEVFSQI--------------
>tr|R5DVP7|R5DVP7_9FIRM NAD-dependent protein deacetylase OS=Ruminococcus sp. CAG:108 GN=cobB PE=3 SV=1
--------------------------------------KSKRIVFFGGAGVSTESGIPDFRSVDGLYNQYPPEQILSHTFFVHKTSE---FFRFYRDKML
CLDKKPNKAHYKLAELEKAG-KLSAVVTQNIDGLHQAAGSKRVYELHGSVLRNYCTKCGRFYD-AEFKN-IPKC-TCG--GIIKPDVVLYEEGLDTVTGA
VNAISKADTLIIAGTSLTVYPAAGFIRY-FG-GDNLVLINRDPTPMDK-NNLVFREKVGELLDKIT-------------
>tr|A0A011WP25|A0A011WP25_RUMAL NAD-dependent protein deacetylase OS=Ruminococcus albus SY3 GN=cobB PE=3 SV=1
--------------------------------------DSKSVVFFGGAGVSTESGIPDFRSVDGLYNQYPPETILSHTFFMDKTEE---FYKFYRDKML
CLTAKPNKAHLKLAEMEKAG-KLTAIVTQNIDGLHQAAGSKNVYELHGSVLRNYCMKCHKPYP-VEDL-GVPKCT-CG--GTIKPDVVLYEEGLDTVEGA
VESISRADCLIIAGTSLTVYPAAGMVRY-FR-GKHLVLINRDPTPMDD-MELVLHEKVGEVLDKIV-------------
>tr|W0U6Q7|W0U6Q7_9FIRM NAD-dependent protein deacetylase OS=Ruminococcus bicirculans GN=cobB PE=3 SV=1
--------------------------------------KSHRIVFFGGAGVSTESGIPDFRSVDGLYNQYPPEQILSHTFFMRHTKA---FYDFYRDKML
CLTAKPNKAHYKLAEMERAG-ILSSVITQNIDGLHTAAGSKKVLELHGSVHRNYCMDCGKFYT-AEDL-GIPKCT-CG--GIIKPDVVLYEEGLDTVTEA
VREISQCDTLIIAGTSLTVYPAAGMVRY-FQ-GDNLVLINRDKTSMDG-SDLVIHDKVGETLDKIV-------------
>tr|R6Q7F5|R6Q7F5_9FIRM NAD-dependent protein deacetylase OS=Eubacterium sp. CAG:251 GN=cobB PE=3 SV=1
--------------------------------------ECNKIVFFGGAGVSTESGIPDFRSVDGLYNQYPPEEILSHTFFYSHTID---FFKFYRDKML
IENVKPNEAHLKLAELEKVG-KLSAVVTQNIDGLHQAAGSKKVYELHGSTLRNYCTKCRKFFD-ADYKN-IPYCDECG--GLVKPDVVLYEEGLDTVNGA
LEAISDADCLIIAGTSLTVYPAASFVRY-FR-GKYLVLINRDETPMDK-NDLVIHDKVGEVLSKIK-------------
>tr|R6IZF7|R6IZF7_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. CAG:217 GN=cobB PE=3 SV=1
--------------------------------------RSRRIVFFGGAGVSTESGIPDFRSVDGLYHQYPPEQILSRSFFDENPAE---FYRFYRSKML
CPNARPNAAHYKLAELEQAG-KCTAVVTQNIDGLHQAAGSRTVYELHGSVLRNHCMHCGRAYG-VEAA-DIPRCA-CG--GIIKPDVVLYEEGLDTVEGA
VHAIARADCLIVAGTSLSVYPAAGFIRY-FQ-GEHFVLINRDPTPADK-LDLVLHQKVGQVLSQIQ-------------
>tr|R6RJ75|R6RJ75_9FIRM NAD-dependent protein deacetylase OS=Eubacterium siraeum CAG:80 GN=cobB PE=3 SV=1
--------------------------------------ESKSIVFFGGAGVSTESGIPDFRSADGLYNQVPPEELLSHEYFFEHTGK---FFEFYREKML
CLDAKPNKAHLKLAELERAG-KLTAVITQNIDGLHTAAGSKTVYELHGSVHRNYCLKCGKSYS-AEDL-GVPHCE-CG--GIIKPDVVLYGENLDTVTGA
LSAIEQCDTLIIGGTSLTVYPAAGFIRY-FG-GRNLVLINMSATPYDS-RDLAIHDKVGEVLDKIK-------------
>tr|R5XJ51|R5XJ51_9FIRM NAD-dependent protein deacetylase OS=Anaerotruncus sp. CAG:528 GN=cobB PE=3 SV=1
--------------------------------------SSNNIVFFGGAGVSTESGIPDFRSVDGLYNQYPPEEILSHDFFWHHTDY---FYRFYRDKLI
CPEAKPNAAHYKLAELEKAG-KLKAVVTQNIDGLHQKAGSKNVFELHGSTLRNYCTDCGKSFD-RQYA-GVPICDYCG--SVIKPDVVLYGESLNTVNGA
INAIASADCLVVAGTSLVVYPAAGFIRY-YK-GDKFVLINKAPTQADS-IDLVIHDSVGKVLSQIE-------------
>tr|R6R6C1|R6R6C1_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. CAG:352 GN=cobB PE=3 SV=1
--------------------------------------ESKSIVFFGGAGVSTESGIPDFRSVDGLYNQFPPETILSHTFFMRNTKD---FYDFYREKML
CLDVKPNKAHLALTKLEKEG-KLKGIVTQNIDGLHQAAGSKNVYELHGSVLRNYCMKCHKFYP-AEYAEGVPHCT-CG--GIIKPDVVLYEEGLNTINES
VKLIANCDMLIIGGTSLNVYPAAGLIQY-FN-GKYLVLINKSETPVDR-KDIVIHDSIGKVLSNVI-------------
>tr|W7UW40|W7UW40_RUMFL NAD-dependent protein deacetylase OS=Ruminococcus flavefaciens 007c GN=cobB PE=3 SV=1
--------------------------------------NSHSIVFFGGAGVSTESGIPDFRSVDGLYSQYPPETILSHTFFMSKTEE---FYRFYRAKML
CLDAKPNAAHLKLAQLEKEG-KLSAVITQNIDGLHQAAGSRKVYELHGSVLRNYCTKCGKFYD-VRYI-GVPKCE-CG--GIVKPDVVLYEEALDTVSGA
VNAIASADTLIIGGTSLNVYPAAGLIRY-FR-GEHLVIINMAPTQMDK-NELLICERIGEVFSRI--------------
>tr|R7BBW6|R7BBW6_9FIRM NAD-dependent protein deacetylase OS=Firmicutes bacterium CAG:341 GN=cobB PE=3 SV=1
--------------------------------------ECESIVFFGGAGVSTESGIPDFRSVDGLYNQYPPEEILSHTFFYNNTGE---FYKFYRDKLI
CKNAKPNPAHLKLAELERAG-KLSAVVTQNIDGLHQKAGSKNVFELHGSTLRNYCTKCGKSFD-INYE-PIPYCDECD--GLVKPDVVLYEEGLDTVNGA
LNAISNADCLIIAGTSLTVYPAASFVRY-FR-GKYLVLINRDETAMDK-NDLVIHDKVGEVLSKIK-------------
>tr|R6C1W4|R6C1W4_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. CAG:245 GN=cobB PE=3 SV=1
--------------------------------------KCDNIVFFGGAGVSTESGIPDFRSKDGLYNQYPPETILSHTFFMNKTEE---FFKFYKLKMN
SLKYQPNITHIKLAELETKG-KLKAVITQNIDGLHQKAGSKVVYELHGSVLRNYCMNCHKFYD-AEYFNGIPRCS-CG--GIIKPDVVLYEEGLDTIENS
IYAIQKADLLIVAGTSLTVQPASGLINF-FR-GRNLVLINRDSTPYDN-KNLVINDSLGKVFSNL--------------
>tr|R6N0W5|R6N0W5_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. CAG:302 GN=cobB PE=3 SV=1
--------------------------------------NSKKIVFFGGAGVSTESGIPDFRSKDGLYNMYPPELILSHSFFYDDTEE---FYKFYKDKMN
SLNYKPNVTHYYLSELEKEG-KLLGVITQNIDGLHSKAGSKKVLELHGSIMDNYCIKCHKYYD-ANYFDDIPRC-TCG--SIIKPNVVLYNESLPVWNEA
IKLIKEADTMIIGGTSLTVFPAAYLIDY-FH-GSNLVLINKDKTSYDD-RTLVINDKLGNVFSKL--------------
>tr|R6HVC4|R6HVC4_9FIRM NAD-dependent protein deacetylase OS=Ruminococcus sp. CAG:177 GN=cobB PE=3 SV=1
--------------------------------------QSHSLVFFGGAGVSTESGIPDFRSVDGLYNQYPPEQMLSHTFFERKTED---FYRFYRDKIL
SYAVKPNAAHKKLAELEERG-ILSAVVTQNIDGLHQAAGSKNVFELHGSVLRNYCTRCGRSFD-IDYI-GVPHCS-CG--GVIKPDVVLYEEALDTVRGA
VSAIASADTLIIAGTSMVVYPAAGLVNY-FN-GKHLVVINMSPTSTDS-RDLLICGKVGEVLGGVE-------------
>tr|E9SHD9|E9SHD9_RUMAL NAD-dependent protein deacetylase OS=Ruminococcus albus 8 GN=npdA PE=3 SV=1
--------------------------------------ESEKVVFFGGAGVSTESGIPDFRSVDGLYNQYPPETILSHTFFLKKTDE---FYKFYRDKML
CKGAKPNKAHLKLAEMEAKG-KLTAVVTQNIDGLHQAAGSKKVLELHGSVLRNYCMECGKYYD-MEYM-GVPKCD-CG--GTVKPDVVLYEEGLDIMEES
ITRISEADCLIIAGTSLTVYPAAGMVRY-FR-GKHLVLINRDPTPMDD-MELVLHDKVGEVLSQIK-------------
>tr|R5L3G5|R5L3G5_9FIRM NAD-dependent protein deacetylase OS=Eubacterium sp. CAG:115 GN=cobB PE=3 SV=1
--------------------------------------ESEKIVFFGGAGVSTESGIPDFRSQDGLYNMYPPEQIISHSFFMADPEE---FFRFYRDRMI
YPAAKPNAAHLKLAELERAG-KLSAVVTQNIDGLHSDAGSRNVIELHGSVRRNHCMKCGKSYG-LEFT-GVPRCS-CG--GIVKPDVVLYEEPLNDINAA
INAISDADVLIIGGTSLAVQPAAGLIRF-FN-GRRLAVINKSPTSADD-EDIVINGSIGETLGSIT-------------
>tr|R5P5S6|R5P5S6_9FIRM NAD-dependent protein deacetylase OS=Eubacterium sp. CAG:603 GN=cobB PE=3 SV=1
--------------------------------------ESNYIVFFGGAGVSTESGVPDFRSVDGLYNQYPPETILSHTFFMRNTEE---FYKFYKDKML
FKDVEPNNAHKALARLEESG-KLKAVITQNIDGLHQAAGSKNVYELHGSVHRNYCMKCHKFYD-FDYY-GVPKCE-CG--GIIKPDVVLYEEGLDILSES
IMHIANADTLIIGGTSLAVYPAAGLIQY-FR-GKNLILINKSTTPMDS-KTLVINDSIGKVLSEV--------------
>tr|R7GJ98|R7GJ98_9CLOT Transcriptional regulator Sir2 family OS=Clostridium sp. CAG:307 GN=BN598_00914 PE=4 SV=1
----------------------------------------KRIVFFGGAGVSVASGIPDFRGANGLYN-KVPEEIISHHYFLENTKE---FYEFYKDNLV
FKNAKPNPCHEALAILEEKG-YLKAIITQNIDGLHQMAGSKNVIELHGSIHRNYCMKCHKFYA-LEDTFSIPRCS-CG--GIIKPDVVLYEEALNVIEKA
IYEISNADTLIVAGTSLVVYPAASFVKF-FR-GRNLIVINLGNIAV-S-GNLKINGRVEDYLNPQN-------------
>tr|R7ITU5|R7ITU5_9FIRM NAD-dependent protein deacetylase OS=Roseburia sp. CAG:303 GN=cobB PE=3 SV=1
--------------------------------------ESDRIVFFGGAGVSTESGIPDFRSVDGLYNQYPPETIISHSFYKKNPKE---FYRFYKDRMI
YQDAKPNKAHYALAKLEQQG-KLSAVITQNIDGLHQMAGSKNVLELHGSIHRNYCEKCGKAYP-LSYA-DIPCCE-CG--GIVKPDVVLYEEGLDIVNHA
LEELRQADMLIVGGTSLVVYPAAGMIDY-YT-GSKMVLINLSATDKDQ-KDLVINGKIGEILDQVV-------------
>tr|R5GPG6|R5GPG6_9FIRM NAD-dependent protein deacetylase OS=Eubacterium sp. CAG:786 GN=cobB PE=3 SV=1
--------------------------------------ESRRIVFFGGAGVSTESGIPDFRSADGLYNQFPPEQIISHSFFLRDPEE---FYRFYRDRMI
YPQAKPNAAHLKLSELERVG-RISAVITQNIDGLHSAAGSRNVIELHGSIHRNHCMKCGKSFP-LEFM-GVPHC-ECG--GIVKPDVVLYEEPLDCINRA
INAISEADMLIIGGTSLAVQPAAGLIRF-FN-GRRLAVINKTPTSADD-EDIVINASIGEALSGIT-------------
>tr|R5J057|R5J057_9FIRM NAD-dependent protein deacetylase OS=Firmicutes bacterium CAG:822 GN=cobB PE=3 SV=1
--------------------------------------ECENIVFFGGAGVSTESGLKDFRSKDGLYNMYPPEEILNHSFFENNTEE---FYNFYKDKLN
ALDILPNVCHKYLAQLEEKG-KLKAIVTQNIDGLHQKAGSKNVLELHGTIYENNCMKCGKSYD-ASYFEGIPKCS-CG--GIIKPDVVLYEEALDIVDEA
VYRISKAELLIVAGTSLTVYPASSFVRY-FK-GKYLVIINNDKTSYDG-MNLVIHDKIGNVFSKLK-------------
>tr|R5JYC8|R5JYC8_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. CAG:632 GN=cobB PE=3 SV=1
--------------------------------------ASSKVVFFGGAGVSTESGIPDFRSVDGLYNQYPPERIISHSYYRSHPEE---FFEFYKDKMI
FTDAKPNAAHIRLAELEREG-HVQAVITQNIDGLHQMAGSKEVLELHGSIHRNYCEKCHRFYD-LDYV-GVPRCE-CG--GIVKPDVVLYEEALNTIEKA
LYYISQAEVLIIGGTSLVVYPAAGMIDY-FR-GKHLVVINKAPTPRDE-NDILIQDSIGKVFSQI--------------
>tr|R5K3I3|R5K3I3_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. CAG:264 GN=cobB PE=3 SV=1
--------------------------------------GSECMVFFGGAGVSTESGIPDFRSVDGLYNQYPPETIISHSFYMRDPEE---FYRFYKDKMI
YQDAKPNMAHKKLAELEAQG-KLAAIVTQNIDGLHQMAGSKNVIELHGSIHRNYCTKCHKFYD-LDYI-GVPKCS-CG--GIIKPDVVLYEEGLNDIENA
IRYISEADTLIIGGTSLVVYPAAGLIRY-FR-GKHLVVINMSPTQTDS-QDLLIADKIGKVLGQL--------------
>tr|R7FP29|R7FP29_9CLOT NAD-dependent deacetylase OS=Clostridium sp. CAG:288 GN=BN588_00594 PE=4 SV=1
----------------------------------------KRIVFFSGAGVSVSSGIPDFRGEHGIYK-YAPEEMISHHFFLEHTKE---FFDFYLKHLV
FLDANENECHKAIAYLEKVG-KVEAVVTQNIDGLHQKAGSKKVIELHGSIHRNHCMKCHKFYD-IKDKFPIPYCS-CG--GIIKPDVVLYEESLNDITNT
IRAISSCDTLIVIGTSLSVYPAASFIDF-FR-GKHLVVINLGQTRNRV-DELIIDGKVENYLNMEN-------------
>tr|R7NQG6|R7NQG6_9FIRM NAD-dependent protein deacetylase OS=Eubacterium sp. CAG:581 GN=cobB PE=3 SV=1
--------------------------------------NSNNIVFFGGAGVSTESGIPDFRSVDGLYNLYPPEQIISHTFFQYKPEE---FYRFYKDKMM
CLDAKPNKAHTFLAKLEEKG-KLSAVVTQNIDGLHQAGGSHTVYELHGSIHRNYCTKCHAFYD-AEFKNLIPKCTKCG--GIIKPDVVLYEEGLDTVTNA
INAISNCDTLIIAGTSLVVYPAASFIRY-FK-GNHLVLINLSETSADK-MDLVIHGKVGEVLSQIK-------------
>tr|R5JVB4|R5JVB4_9FIRM NAD-dependent protein deacetylase OS=Coprococcus sp. CAG:782 GN=cobB PE=3 SV=1
--------------------------------------ESDNIVFFGGAGVSTESGIPDFRSVDGLYNQYPPETIISHSFYRRNPEE---FYRFYKDKML
FPEAKPNKAHMKLAELEAAG-KLKAVITQNIDGLHQMAGSRRVIELHGSVHRNYCERCHKFYD-LRYI-GVPKCS-CG--GTIKPDVVLYEEGLNDIEDA
IHYISEADTLIIGGTSLVVYPAAGLIRY-FR-GRHLVVINMSPTQSDR-EDLLITDKIGSVLDQIH-------------
>tr|G8LZ43|G8LZ43_CLOCD NAD-dependent protein deacetylase OS=Clostridium clariflavum (strain DSM 19732 / NBRC 101661 / EBR45) GN=cobB PE=3 SV=1
--------------------------------------QSDNIVFFGGAGVSTESGIPDFRSANGLYNEYSPEEILSHTFFMKHTDK---FYEFYKSKMI
YKDAKPNNAHIALAKLEEEG-KLKAVITQNVDGLHQLAGSKMVLELHGSIHRNYCMNCHKAFQ-LSYLEQVPKCDDCG--GIVKPDVVLYEEALDVLEAS
LEYISKADVLIVGGTSLSVYPASGLVSY-YR-GNKLVLINKTQTPYDV-RNLILRESIGEVLSKAC-------------
>tr|F2NUY1|F2NUY1_TRES6 NAD-dependent protein deacetylase OS=Treponema succinifaciens (strain ATCC 33096 / DSM 2489 / 6091) GN=cobB PE=3 SV=1
--------------------------------------KSQKIVFFGGAGVSTESGIPDFRSVDGLYNQYPPETILSATFFHSNPKE---FYRFYREKLL
VFGIKPNITHFKLAELEKQG-KLLAVVTQNIDGLHQAAGSKKVFELHGSVLRNYCTKCGEFYD-EKYASGLPLCEKCG--SLIKPDVVLYEESLKIVSGA
IKAIGGADLLIIGGTSLTVYPAAGMIHY-FR-GENIVLINRDPTPSDG-INLVLHESLGNVFSKL--------------
>tr|U4KR96|U4KR96_9MOLU NAD-dependent deacetylase OS=Acholeplasma palmae GN=npdA PE=4 SV=1
----------------------------------------KYIVFFGGAGVSTESGLKDFRGDTGLYKEITPEVILSHSYFVKNTED---FFEYYKEVFL
RPRVNPNAAHKVLAQLEKMG-KLKSIITQNIDNLHQEAGSKKVIELHGSVYRNYAIDTKERYD-GIDILGVPKTA-DG--QIIRPDVILYEEPLNTIDDA
INEIKKADCLIVAGTSLVVYPAAGLLRH-FN-GKYLIGINRNLIDVP----YFIKGDIGKVLSQIN-------------
>tr|R5LH13|R5LH13_9FIRM NAD-dependent protein deacetylase OS=Butyrivibrio crossotus CAG:259 GN=cobB PE=3 SV=1
--------------------------------------ESDNIVFFGGAGVSTESGIPDFRSVDGLYNQYPPETILSHSFFMRNTEE---FYRFYRDKML
YKDAKPNKAHYALAELEKQG-KCKAVITQNIDGLHQAAGSKEVLELHGTVKKNYCMKCHKFYG-EEYM-GVPKCD-CG--GIIKPYVVLYEESLDVIEKA
VDYIRHADVLIIAGTSLTVYPAAGLIDY-YR-GNKLVLINKSVTPKDN-IDLVIHEPVGKTLGEIV-------------
>tr|R6MMK0|R6MMK0_9FIRM NAD-dependent protein deacetylase OS=Firmicutes bacterium CAG:41 GN=cobB PE=3 SV=1
--------------------------------------SSDNIVFFGGAGVSTESGIPDFRSVDGLYNMYPPETILSHTFFMNNTEE---FYKFYRDKLI
VKGVKPNKAHIALAKLEEKG-KLKAVITQNIDGLHQMAGSKNVLELHGSTLRNYCMDCGKSYD-IDYE-GVPKCE-CG--GIIKPDVVLYEEMLNTITKL
VQYISNADVLIIGGTSLNVYPAAGFINY-FK-GSKLVIINKAATSADK-NDLVISEPIGEVLGSLK-------------
>tr|R6YNX4|R6YNX4_9FIRM NAD-dependent protein deacetylase OS=Roseburia sp. CAG:309 GN=cobB PE=3 SV=1
--------------------------------------DSDNIVFFGGAGVSTESNIPDFRSVDGLYNQYPPETILSHTFFMRNTPE---FYRFYRNKMI
FPDAEPNKAHLALAELEKQG-KLKAVITQNIDGLHQKAGSTEVLELHGSVLRNYCMKCGKFYN-LQDISGVPKCS-CG--GIIKPDVVLYEEGLDVLEKA
VNYIKNADILIIGGTSLAVYPAAGLIDY-YR-GNKLVLINKSETSRDA-HNLVINDAIGKVFSQLL-------------
>tr|A0A0H5SZA3|A0A0H5SZA3_9FIRM NAD-dependent protein deacetylase OS=Herbinix hemicellulosilytica GN=cobB PE=3 SV=1
--------------------------------------ESDNIVFFGGAGVSTESGIPDFRSVDGLYNQYPPETILSHSFFMEHTEK---FYDFYRDKMI
YTDAKPNITHYKLAQLERQG-KLKSVITQNIDGLHQMAGSMNVLELHGSVWRNFCMKCHRFYP-LEKI-KVPHCD-CG--GIIKPDVVLYEESLNTVSKA
VKAISMADMLIIGGTSLNVYPAAGLIRF-YK-GGKMVLINKSVTPYDN-EDLLIQTGLGEVFKEL--------------
>tr|E7MPI4|E7MPI4_9FIRM NAD-dependent protein deacetylase OS=Solobacterium moorei F0204 GN=cobB PE=3 SV=1
--------------------------------------NSNHIVFFTGAGVSTASGIPDFRSTDGLYN-FPPEEILSHHFFKQHTEE---FFRFYRDKML
YPDVKPSYVHAYIASLEKRN-KKVTVITQNIDGLHQLAGSTNVLELHGSVLRNTCMQCHAKYS-LDD--TIPHCPKCN--GIIKPNVVLYEEGLDILNQS
LYALQTADTCIVLGTSLVVYPAAGLLRY-FG-GNTLVLINRDQTSYDS-TDLTIHDDFINVFPNLK-------------
>tr|R6QZS6|R6QZS6_9FIRM NAD-dependent protein deacetylase OS=Butyrivibrio sp. CAG:318 GN=cobB PE=3 SV=1
--------------------------------------ESDNIVFFGGAGVSTESNIPDFRSVDGLYNQYPPETILSHTFFMRHTDE---FFDFYRDKML
YPDAVPNKAHIALAKLEKLG-KCKAVVTQNIDGLHQAAGSREVLELHGSVLRNYCMKCLRFYD-ESAI-GIPRCE-CG--GIIKPDVVLYEEGLDTLTKA
VKYISEADVLIVAGTSLTVYPAAGLIDY-YH-GNKLILINKSATARDS-VDIVINDAVGETLDYCV-------------
>tr|R6NAU2|R6NAU2_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. CAG:413 GN=cobB PE=3 SV=1
--------------------------------------SSKRAVFFGGAGVSTESGIPDFRSADGIYM-YPPEEILSHMFFMQHTEE---FYEFYRKHL-
-CGVEPNAAHLKLAELERAG-ILAAVVTQNIDGLHTKAGSKTVYELHGSTLRNHCMKCGKFYD-ADY--GVPKC-SCG--GVIKPDVVLYQEALDTVDGA
IRAIKDADTLIVAGTSLTVYPAASFIRY-FK-GNDLIIINRDPTPQDG-SDLVIHDSIGKVLSKIN-------------
>tr|R9NCE0|R9NCE0_9FIRM NAD-dependent protein deacetylase OS=Dorea sp. 5-2 GN=cobB PE=3 SV=1
--------------------------------------DSSQIVFFGGAGVSTESDIPDFRSADGLYQQYSPEQIVSHSFFVQNTEG---FYEFYKDKMM
FLDALPNQAHLKLAELEKAG-KLTAVITQNIDGLHQAAGSKNVLELHGSIHRNYCQKCGKFYD-AAYKGGIPKCS-CG--GRIKPDVVLYEEGLDVIRKS
IQAISRADTLIIGGTSLVVYPAAGFIDH-FR-GKHLVVINKSATAREV-GELSIAAPIGEVLGRIV-------------
>tr|R7FS32|R7FS32_9FIRM NAD-dependent protein deacetylase OS=Dorea longicatena CAG:42 GN=cobB PE=3 SV=1
--------------------------------------DSKRIVFFGGAGVSTESNIPDFRSADGLYQQYSPEQIVSHSFFVRNPEG---FYEFYKEKMM
FLDAKPNAAHLKLAELEETG-KLTAVITQNIDGLHQAAGSKNVLELHGSIHRNYCMKCHKFYD-AAYKNGIPRCT-CG--GMIKPDVVLYEEGLDVISRS
IKAISEADTLIIGGTSLVVYPAAGFIDY-FR-GKHLVVINKSATAREV-GKLTIAAPIGEILGRVH-------------
>tr|G1WS31|G1WS31_9FIRM NAD-dependent protein deacetylase OS=Dorea formicigenerans 4_6_53AFAA GN=cobB PE=3 SV=1
--------------------------------------DSENIVFFGGAGVSTESNIPDFRSADGLYQQYSPEQIVSHTFFMRNTEG---FYEFYKEKMM
FLDAKPNAAHKKLAELEQAG-KLKAIITQNIDGLHQAAGSKNVYEIHGSIHRNYCQKCGKFYD-AAYKNGVPHCE-CG--GVIKPDVVLYEESLDMIDKS
IRAISQADTLIIGGTSLVVYPAAGFVDY-FR-GKHLVVINKSDTAKSV-RELTIAAPIGEVLSQIT-------------
>tr|R6WEN9|R6WEN9_9FIRM NAD-dependent protein deacetylase OS=Firmicutes bacterium CAG:227 GN=cobB PE=3 SV=1
--------------------------------------GHQNIVFFGGAGVSTESGIPDFRSVDGLYHQYPPETILSHTFFVRKPKE---FYRFYKEKML
CEGAKPNAAHKKLAQLEKAG-KLKAVITQNIDNLHQMAGSKKVYELHGSVYRNYCTKCGAFYD-FSYKHGIPVCKKCG--GIIKPDVVLYEEGLDVIEGA
VQAIREAEVLIIGGTSLAVYPAASLIDY-FK-GDALVVINRDKTPRDK-MDLVINEPIGAVFEQIR-------------
>tr|F3AEX9|F3AEX9_9FIRM NAD-dependent protein deacetylase OS=Lachnospiraceae bacterium 6_1_63FAA GN=cobB PE=3 SV=1
--------------------------------------ESKNIVFFGGAGVSTESGIPDFRSVDGLYHQFPPEVILSHTFFRRKPAE---FYRFYQAKML
CDTAKPNAAHKKLAQLEEQE-KLKAIVTQNIDNLHQMAGSKNVLELHGSVYRNHCVKCRSFYD-FAYKKGIPRCSKCG--SIIKPDVVLYEEALDVVNAS
IHAIAHADTLIIGGTSLSVYPAASLIDY-FS-GKHLVVINRDKTPQDE-MELVINRPIGEVFEQIK-------------
>tr|R6RMN8|R6RMN8_9FIRM NAD-dependent protein deacetylase OS=Firmicutes bacterium CAG:424 GN=cobB PE=3 SV=1
--------------------------------------ETENIVFFGGAGVSTESGIPDFRSVDGLYHQYPPETILSHRFFMRKPEE---FYRFYKAKML
CDTAVPNAAHKKLAEMEQKG-KLKAIVTQNIDNLHQMAGSKHVLELHGSVYRNYCMKCGAFYD-FAYKKGVPKCEKCG--GMIKPDVVLYEEGLNTVRKS
VQAISEAGVMIIGGTSLSVYPAASLIDY-FQ-GRYLVVINRDETPRDR-VDLVINAPIGEIFEQIH-------------
>tr|D1PJK5|D1PJK5_9FIRM NAD-dependent protein deacetylase OS=Subdoligranulum variabile DSM 15176 GN=cobB PE=3 SV=1
--------------------------------------KSKNMVFFGGAGVSTESGIPDFRSVDGLYHQYPPEVMLSHSFYETHTAE---FFDFYRNKLI
VHGAKPNAAHLRLARLERQG-VCKAVVTQNIDGLHQAAGSRTVYELHGSTLRNYCTRCGKFYP-VEFEQGIPRCTECG--GIVKPDVVLYEEGLDTMENA
VRAIAAADTLIVGGTSLAVYPAAGLLRY-FR-GDDLVVINKQPTPADS-MTLVLNQPIGQALREEG-------------
>tr|D4KBL8|D4KBL8_9FIRM NAD-dependent protein deacetylase OS=Faecalibacterium prausnitzii SL3/3 GN=cobB PE=3 SV=1
--------------------------------------KSSSIVFFGGAGVSTESGIPDFRSVDGLYHQYPPETILSHTFWEENPEE---FYRFYRDKLI
VKGAKPNAAHLRLAKLEQQG-KLRAVVTQNIDGLHQAAGSKTVYELHGSTLRNYCTRCGKFYD-VDFA-GVPRCTECG--GIVKPDVVLYEEGLDVLSGA
VDAIRHADTLIIGGTSLVVYPAAGLIRY-FR-GDNLVVINMQPTGADA-SDLCIAKPIGQVLSEDI-------------
>tr|R7KF99|R7KF99_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. CAG:451 GN=cobB PE=3 SV=1
----------------------------------------KKTVFFGGAGVSTASGLQDFRGSNGLYKEYPPEEILSHTFFMKHTDL---FYEFYKEKLN
SLNYKPNIIHKTLKLMEDKN-LLSSIITQNIDGFDKMAGSRNVLELHGSILRNYCLNCHKFYS-GDYFKSIPKCS-CG--GIIKPDVVLYEEALDVLTEA
IQEVSEADLLIVGGTSLQVYPASSLVTY-FR-GKHLVLINKDETPYDY-LDIVIHDDLASVFEKIN-------------
>tr|A0A0C1UIW3|A0A0C1UIW3_9CLOT NAD-dependent protein deacetylase OS=Clostridium argentinense CDC 2741 GN=cobB PE=3 SV=1
--------------------------------------NSNNIVFFGGAGVSTESSIPDFRSAEGLYNSYNPEEILSHSFFIRYPED---FFRFYKEKML
YPNASPNSSHYALSKLEKMG-KLKAVITQNIDGLHQLAGSKNVLELHGSVCKNFCVKCNKKFS-LDYLNLVPYCDNCG--GIVRPDVVLYEESLNILASS
IEAITNADTLIVGGTSLVVYPAAGLIRY-FN-GKNLVLINKSSTPYDN-YHLVINESIGKALNFIN-------------
>tr|R7L0H1|R7L0H1_9FIRM NAD-dependent protein deacetylase OS=Ruminococcus sp. CAG:353 GN=cobB PE=3 SV=1
--------------------------------------SSDNIVFFGGAGVSTESGIPDFRSVDGIYNMYPPETILSRTFFCNHISE---FYEFYKDKML
YLDAKPNKAHLALAELERRG-KLKAVITQNIDGLHQAAGSKTVYELHGSVHRNYCVRCGAMFD-AEYK-FIPECAQCG--GLIKPDVVLYQESLNTVDCA
IEAIENCDVLIIGGTSLSVYPASGLIEY-YK-GNKLVLINKSTTQYDD-RDLLISESIGETLDYCI-------------
>tr|F9M1P6|F9M1P6_STRPA Transcriptional regulator, Sir2 family OS=Streptococcus parasanguinis SK236 GN=HMPREF9962_1598 PE=4 SV=1
--------------------------------------QSHRIVFFGGAGVSTESNIPDFRSSDGVYSVLTAEQLVSHTMFERYPED---FFVFYKKYLL
YPDAKPNAAHRYLARLEETG-KLKAVVTQNIDSLHEMAGSKKALKLHGSADRNYCTGCQRFYD-LEALAPVPHCLNCG--KVVKPDVTLYEEPLDVFSQA
AQAIQEADLLIIGGTSLVVYPAASLIQY-FR-GKKLVVINKTSIPQDK-QDLVIEGKIGEVFSQLR-------------
>tr|R7F409|R7F409_9BACI NAD-dependent protein deacetylase OS=Bacillus sp. CAG:988 GN=cobB PE=3 SV=1
----------------------------------------KKIVFFGGAGVSTESGIKDFRSEDGLYSEYPPEYMLSIDLFQKDPKT---FFDFYKEKLN
CLNAKPNITHKYLKKLEDRG-KLQAIITQNIDGLHQKAGSKNVYEIHGTIYQNHCTKCHKGYP-PENFHGIPTCD-CG--GVIKPDVVLYGEMLPYS-KA
IASLKGADMLIVAGTSLTVSPANQLVMM-FE-GKYLVLINRTPTPYDS-ITLTIHENLKDVFNKIE-------------
>tr|R5A0U4|R5A0U4_9CLOT NAD-dependent deacetylase OS=Clostridium sp. CAG:1000 GN=BN451_01086 PE=4 SV=1
----------------------------------------NNIVFFGGAGVSTESGIKDFRSKDGLYNLYPPELILSSNFFYNNTEE---FYKFYKDKLN
CLNSEPNIIHNYLTKLEQKG-KLKGIITQNIDGLHTKAGNKKVYELHGTIYNNHCIKCGKYYD-AKYFNGIPKCK-CG--GIIKPDVTLYGEMLDILNMS
IHLISTCDTLIVAGTSLLVEPASSLIKL-FK-GKNLVILNRSNTKYCD-ISLVINDSLGNIFKQLH-------------
>tr|R5N509|R5N509_9FIRM NAD-dependent protein deacetylase OS=Eubacterium sp. CAG:180 GN=cobB PE=3 SV=1
--------------------------------------ESDYVVFFGGAGVSTESGIPDFRSADGLYNMVPPEVILSHSYFMSHPEE---FYRFYRDKLL
NPDVKPNIAHLKLAEMEQKG-KLKAVITQNIDGLHEKAGSKNVYNLHGSVYYNHCMKCGKAYT-FTDL-GVPHCT-CG--GIIKPDVVLYEEPLNTVNGA
VRHIMNADMLIVAGTSLTVYPAAGLIRY-FR-GRNSVLINRDANVGDD-ESLVIHGKVGEVLGGLV-------------
>tr|C6JH24|C6JH24_9FIRM NAD-dependent protein deacetylase OS=Ruminococcus sp. 5_1_39BFAA GN=cobB PE=3 SV=1
--------------------------------------KYDNIVFFGGAGVSTESGIPDFRSQDGLYHQYPPETILSHTFFMRKPEE---FFKFYRDKML
CDTAKPNAAHLKLAELEQAG-KLKAVITQNIDNLHQMAGSKKVLELHGSVYRNYCMKCHRFYD-FAHKAGVPRC-ECG--GIIKPDVVLYEEGLDTINEA
VKAISEAQVLIIGGTSLAVYPAAGLIDY-FR-GEHLVVINKSPTPRDR-YDLLIQEPIGQVFAQIH-------------
>tr|D4LNF6|D4LNF6_9FIRM NAD-dependent protein deacetylase OS=Ruminococcus sp. SR1/5 GN=cobB PE=3 SV=1
--------------------------------------ESRNIVFFGGAGVSTESGIPDFRSQDGLYNQYPPETILSHTFFMRKPEE---FFKFYRDKML
CDTAKPNAAHLKLAEMEQTG-KLKAVITQNIDNLHQMAGSKKVLELHGSVYRNHCVKCGKSYD-FKYKEGVPRC-SCG--GMIKPDVVLYEEGLDTIQES
VRVISEAEVLIIGGTSLAVYPAAGLIDY-FR-GNHLVVINKAPTPRDK-YDLLIKEPIGQVFSQIR-------------
>tr|R6KZL4|R6KZL4_9FIRM NAD-dependent protein deacetylase OS=Blautia sp. CAG:237 GN=cobB PE=3 SV=1
--------------------------------------QHDNIVFFGGAGVSTESGIPDFRSQDGLYHQYPPETILSHTFFLSHPDE---FYKFYRDKML
CDTARPNAAHLKLAELEEAG-KLKAVITQNIDNLHQMAGSHKVLELHGSVYRNHCMRCGKFYD-FDYKHGVPRC-ECG--GMIKPDVVLYEEGLDTIQDS
VRAISEAQVLIIGGTSLAVYPAAGLIDY-FR-GDALVVINKSSTPRDR-NDLLIKEPIGQVFSQIK-------------
>tr|R5WSA3|R5WSA3_9FIRM NAD-dependent protein deacetylase OS=Blautia sp. CAG:257 GN=cobB PE=3 SV=1
--------------------------------------RYDNLVFFGGAGVSTESGIPDFRSVDGLYNQFPPETILSHTFFMRRPEE---FYKFYRDKML
CDTAKPNGAHLKLAELEKAG-KLKAVITQNIDNLHQMAGSRRVMELHGSVYRNYCMKCGKFYD-FSYKNGVPHC-ECG--GIVKPDVVLYEEGLDTLTDS
VRAISQAQVLIIGGTSLAVYPAASLIDY-FR-GECLIVINKAPTPRDR-SDLLIKEPIGQVFSQIK-------------
>tr|R6D4C0|R6D4C0_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. CAG:594 GN=cobB PE=3 SV=1
----------------------------------------KKTVFFGGAGVSTESGIKDFRSKDGLYSEFPPEEILSHHFFYTNPKY---FYKFYREKLN
PTGYKPNVVHKTLAIMEEKG-LLSSIITQNIDGLHEMAHSKNVLNLHGTVYSNTCTKCHKKYD-LKYLEEIPLCS-CG--GIIKPDVVLYEEPLDTLDKA
INEIKSADTLIIGGTSLLVYPAASLINY-FN-GKHIILINKEETKSDY-KDIVIHDKLGNVFKKIK-------------
>tr|F1TAT2|F1TAT2_9FIRM NAD-dependent protein deacetylase OS=[Clostridium] papyrosolvens DSM 2782 GN=cobB PE=3 SV=1
--------------------------------------NADSIVFFGGAGMSTESGIPDFRSENGLYMTYSPETMLSHSFFVSHTDE---FFKYYTTKMI
CKEAKPNSGHIALAKLEEAG-RLKAVVTQNIDGLHQLAGSKKVFELHGSVHRNYCTKCRSFYD-LDYLNAIPRCVKCN--SVIKPDVVLYEESLDVVSGA
INSIRTADVLIIGGTSLVVYPAAGLIDY-FR-GKKLVLVNKSTTPYDS-RDLVINDSVGKVLETAV-------------
>tr|U4R4E1|U4R4E1_9FIRM NAD-dependent protein deacetylase OS=[Clostridium] papyrosolvens C7 GN=cobB PE=3 SV=1
--------------------------------------NAGSIVFFGGAGMSTESGIPDFRSENGLYMTYSPETMLSHSFFVSHTDE---FFKYYKTKMI
CREAKPNAGHLALAKLEESG-RLKAVVTQNIDGLHQLAGSKNVYELHGSVHRNYCTECRTFYD-LDYFNGTPRCMKCN--SIVKPDVVLYEEALDVVSGA
INAIRNADVLIIGGTSLVVYPAAGLIDY-FR-GKKLILVNKSPTPYDS-RDLVINDSVGKVLENAV-------------
>tr|A0A0F3FQ06|A0A0F3FQ06_9CLOT NAD-dependent protein deacetylase OS=Clostridium baratii GN=cobB PE=3 SV=1
--------------------------------------NSNNIVFFGGAGMSTESGIPDFRSSGGLYNDISPEQILSHSFFFDHTEQ---FYNFYRNKMI
YTDAKPNKGHIALAKLEDMG-KLKAVITQNIDGLHQAAGSKRVYELHGSVHRNYCTNCNKFYP-LDFLSGVPKCTECS--SIVKPDVVLYEEPLDVLNES
IKAISNADTLIIGGTSLVVYPAASLIRY-FR-GKNLILINKSSTQYDH-LTLCINDKIGEVLSQVV-------------
>tr|S0FM42|S0FM42_9FIRM NAD-dependent protein deacetylase OS=[Clostridium] termitidis CT1112 GN=cobB PE=3 SV=1
--------------------------------------GSNNIVFFGGAGMSTESGIADFRSENGLYKTYPPETMLSHSFFVSHTAE---FFKYYKEKMI
FKNASPNPGHKALAILEEKG-KLKAVITQNIDGLHQLAGSKKVYELHGSIHRNFCMNCNKFYG-LEYVGDIPLCTVCG--SIIKPDVVLYEEALEVVNGA
VSAIKQADVMIIGGTSLVVYPAAGLITY-FQ-GSKLVLINKSPTPYDS-KDIVINDSAGKILGTAV-------------
>tr|B8I377|B8I377_CLOCE NAD-dependent protein deacetylase OS=Clostridium cellulolyticum (strain ATCC 35319 / DSM 5812 / JCM 6584 / H10) GN=cobB PE=3 SV
--------------------------------------NADSIVFFGGAGMSTESGIPDFRSENGLYVTYPPETMLSHSFFVSHNDD---FFKFYRTKMI
FRDAKPNAGHLALAKLEETD-RLKAVITQNIDGLHQLAGSKIVYELHGSVHRNYCTKCRTFYD-LDYVNGTPRCIKCS--SVIKPDVVLYEESLDVVSGA
IDAIRNADVLVIGGTSLVVYPAAGLIDY-FK-GKKLVLVNKSSTPYDS-RDLVIHDSVGKVLGTAV-------------
>tr|C0ESD2|C0ESD2_9FIRM NAD-dependent protein deacetylase OS=[Eubacterium] hallii DSM 3353 GN=cobB PE=3 SV=1
--------------------------------------GTDNLVFFGGAGVSTESGIPDFRSTDGLYSQFPPETIVSHTFFMKRNKD---FFDFYKDKMM
ALDAKPNAAHYKLAEWEAQG-KCRAVVTQNIDGLHQMAGSKNVLELHGSIHRNYCMRCGKFFD-AAYKNGAPKCDECG--GLIKPDVVLYEEGLDVISKT
IHYISQADVLIIGGTSLVVYPAAGLIDY-FK-GSHLILINKSATQRDS-QDLVINDKIGEVFGQL--------------
>tr|R6MXU6|R6MXU6_9CLOT NAD-dependent protein deacetylase OS=Clostridium leptum CAG:27 GN=cobB PE=3 SV=1
--------------------------------------KSRAMVFFGGAGVSKESGIPDFRSVDGLYHQYPPETILSRSFYEKNPEE---FYRFYRDKML
YLDAEPNPAHKKLAQWEREG-RLLAVITQNIDGLHQKAGSRNVLELHGSVHRNYCRRCGKLFD-AQYLRGVPRCDQCG--GAVKPDVVLYEEALDVLQKA
AGALRQADLLIVGGTSLTVYPAAGLLRY-FQ-GSRLAVVNQTALPLDQ-EDLLIQGQIGQVFSQL--------------
>tr|E2ZBJ5|E2ZBJ5_9FIRM NAD-dependent protein deacetylase OS=Megasphaera micronuciformis F0359 GN=cobB PE=3 SV=1
--------------------------------------NSDNIVFFGGAGVSTESGIPDFRSVDGLYNQFPPETILSHTFYENNKEE---FYRFYHDKML
CLNAKPNAAHLKLAEWERAG-KVKAVITQNIDGLHQKAGSHNVLELHGSVHRNRCERCGAFFD-AEYK-GIPRCNSCG--GPIKPDVVLYEESLDVITET
IRYIQKADMLIIGGTSLVVYPAAGLVHY-YK-GHKLVLINKGETGLDT-QDLVIREPIGKVFSQVK-------------
>tr|U7UDH4|U7UDH4_9FIRM NAD-dependent protein deacetylase OS=Megasphaera sp. BV3C16-1 GN=cobB PE=3 SV=1
--------------------------------------ESDNIVFFGGAGVSTESGIPDFRSVDGLYNQFRPETILSHTFYVHNKDE---FFRFYHDKML
CLDARPNAAHLKLAELERAG-KLKAVITQNIDGLHQKGGSKNVLELHGSVHRNYCEHCHKFFD-AHYK-SVPVCNACG--GPVKPDVVLYEEGLDVVEQA
LYYISHADMLIIGGTSLVVYPAAGFIRY-YK-GHKLVLINKSPTDFDT-SDLVISDAIGNVFSQLV-------------
>tr|J1H6Q8|J1H6Q8_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. MSTE9 GN=cobB PE=3 SV=1
--------------------------------------ESSRIVFFGGAGVSTESGIPDFRSVDGLYHQYPPEEMLSHSFYVRHTAE---FFDFYRKKML
CLDAQPNAAHRKLAELEQAE-KLSAVVTQNIDGLHQKAGSRRVYELHGSVHRNYCQKCHKEYD-AEFL-GIPTC-TCG--GTIKPDVVLYEEGLDVINGA
VTAIRKADMLIIGGTSLAVYPAAGLIHY-FG-GSRLVVINRSSTPADQ-SALMISDPIGEIFSQVK-------------
>tr|A0A011VQT7|A0A011VQT7_RUMAL Uncharacterized protein OS=Ruminococcus albus SY3 GN=RASY3_13905 PE=4 SV=1
----------------------------------------ENIVFFGGAGVSTESGLPDFRGEKGLYRQLPPESYFSLRLLKYDPEE---FFKFQRKRIL
GYDVKPNAAHLKLAEWEKQG-KLRAIITQNIDGLHQEAGSKKVIELHGNIKHCHCMVCHKSYK-ISAMEGIPRCKICR--GIIKPDTVLYGEKLDLLEKA
ADHIRKADMLIVGGTSLTVTPAVSLVHE-CK-DKPLVIINLGLTPLDG-RNIRIYDKIGKVFSAL--------------
>tr|R5KLY8|R5KLY8_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. CAG:678 GN=cobB PE=3 SV=1
--------------------------------------QSNRIVFFGGAGVSTESGIPDFRSVDGLYHQYPPEEILSHTFFEKHTAY---FYKFYRDKML
CLNAEPNAAHRKLAQLEKAG-KLLAVVTQNIDGLHQKAGSKNVFELHGTTLQNHCTSCGKFFT-AEYK-DIARCDSCG--GVIKPDVVLYEESLDTINGA
VAAISSADCLIVAGTSLVVYPAAGFIRY-FK-GKHFVLINKTPTPADS-LELVIHDSVGKVLSQIR-------------
>tr|E3PXH9|E3PXH9_CLOSD NAD-dependent protein deacetylase OS=Clostridium sticklandii (strain ATCC 12662 / DSM 519 / JCM 1433 / NCIB 10654) GN=npdA PE=3
--------------------------------------ASENIVFFGGAGVSTESNIPDFRSEEGIYNIFPPETMLSHSFFINQTSL---FYDFYKTSMI
FPNARPNLAHYTLAKLEQMG-KLNAVITQNIDGLHQAAGSNNVLELHGSIHRNYCMGCHKFFD-LDYLSDVPLCDVCS--EIIKPDVVLYEEGLDVIEKS
VSAIQNADTLIIGGTSLSVYPAAGLIDY-YR-GDNLILINKGEVYKKS-KKLVFRDSVGEVLSLAL-------------
>tr|R6NF81|R6NF81_9FIRM NAD-dependent protein deacetylase OS=Acidaminococcus intestini CAG:325 GN=cobB PE=3 SV=1
--------------------------------------ESQNIVFFGGAGVSTESGIPDFRSIDGLYHQFPPETILSHTFFEAHPDE---FYRFYHDKML
CLDAKPNAAHKKLTQWERDG-RLKAVITQNIDGLHQAAGSRNVLELHGSVHRNYCQKCHKFFD-AAYR-GIPRCDTCG--GVIKPDVVLYEEGLDTLERA
VSYIRQADILIVGGTSLVVYPAAGLIRY-YQ-GKKLVLINKGTTAYDQ-DQLVISAAIGKVMEQLP-------------
>tr|G5F212|G5F212_9ACTN NAD-dependent protein deacetylase OS=Olsenella sp. oral taxon 809 str. F0356 GN=cobB PE=3 SV=1
--------------------------------------GAGNTVFFGGAGVSTASGIPDFRSADGLYNQYPPEVMLSHGFYVEHTRE---FFDFYRSRMC
APDAKPNQAHLKLAELEREG-LVSAVVTQNIDGLHQAAGSRNVIELHGSTHRNVCQRCGHVHS-QEWLKGVPRCEACG--GPVKPDVVLYEEALDVITAA
IRAIASCDLLIVGGTSLVVYPAAGLLRY-FG-GDKLAICNLQPTPQDA-SDLVCACDIARAFDW---------------
>tr|R6B9M3|R6B9M3_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. CAG:524 GN=cobB PE=3 SV=1
----------------------------------------NNIVFFGGAGVSTASGLKDFRSKDGLYNEVSPEFMLSVSCFYSFTKE---FYKYYKANMN
SLNVKPNIVHEYLAKLEQLG-KLKAIITQNIDGLHQKAGSKNVLELHGTIYKNHCIKCGKEYS-AEYFNDIPRCE-CG--SIIKPNVVLYGEMLPFV-LA
EKYISECDLLIVAGTSLIVEPAASLINY-FR-GKNLVIINNDETPYDK-RTLIINEDLTSVFKLLS-------------
>tr|R5LIV7|R5LIV7_9MOLU NAD-dependent protein deacetylase OS=Mycoplasma sp. CAG:877 GN=cobB PE=3 SV=1
----------------------------------------KNIVFFGGAGVSTASGIKDFRGKNGLYKKMPPEYMLSSALFYSKPDV---FYDYYKENMN
CTEAKPNVVHKYLAKLEKDG-KLAAVVTQNIDGLHKKAGSHNVLEIHGTIYKNHCIDCGREYK-ADYFNGVPKCS-CG--GIIKPDVTLYGEMLPFE-VA
TKYIYCADLLIVSGTSLTVEPAASLVKI-FG-GKNLVIINDSPTPYDD-ISLVIRDDMVEIFKKLK-------------
>tr|R6GRR2|R6GRR2_9FIRM NAD-dependent protein deacetylases SIR2 family OS=Firmicutes bacterium CAG:582 GN=BN721_00494 PE=4 SV=1
----------------------------------------CDIVFFDGAGTSTLSGIKDFRGKNGIYKMISPEYLLSINCLENNPFL---FYDFYKSNLN
CLDATPNIIHEYLKCLDNQN-KLRCVITQNIDGLHKRAGLTNVLELHGTIYKNHCMKCGKEYE-ASYFSDIPVCS-CG--GIIRPDVVLYGESLTYY-EA
IKVVSSCETLIVAGSSLTVNPAASLVSL-FN-GKNLIILNDNVTPYDR-CTLVIHDDLKNIFKNLK-------------
>tr|R6Y740|R6Y740_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. CAG:433 GN=cobB PE=3 SV=1
----------------------------------------NNIVAFTGAGVSTLSGIKDFRGKNGLYKEHSAEYYLSSRCFFLEPDT---FYKFYKSNMN
VLDKEPNIVHKYLTKLEKDG-KLKAVVTQNIDGLDKKSGTKNVLEIHGTIYKNYCAKCGKEYS-AEFFNGVPYCD-CK--GIIKPYVVLYGEMLNFE-KA
IYYINNADTLIVLGSSLTVEPAASLVRN-FS-GNNLIIINENDTPLDE-YTLVTHENLENVISKLN-------------
>tr|E6MGV3|E6MGV3_9FIRM NAD-dependent protein deacetylase OS=Pseudoramibacter alactolyticus ATCC 23263 GN=cobB PE=3 SV=1
--------------------------------------ASDNIVFFGGAGVSTASGIPDFRSAGGIYSQFTPEEMVSHSFFVHHPED---FFDFYRDKMV
YPDAEPNGCHKALAKLERMG-KIKAVVTQNIDGLHQKAGSEIVFELHGSVLRNYCTHCHAFYD-DKWMAGVPKCEKCG--ATVKPDVVLYEEALDQINGA
VAAIEKADTLIVGGTSLIVYPAAGLIHY-FR-GRHLVEINKSATSADN-AELVIRDDIAKVMAEAV-------------
>tr|B9E751|B9E751_MACCJ Uncharacterized protein OS=Macrococcus caseolyticus (strain JCSC5402) GN=MCCL_1312 PE=4 SV=1
----------------------------------------EKIVFFGGAGVSTESGIPDFRSADGIFMQHSPEEIISIDFFNKYPKQ---YFKFHFDKLV
YPHAKPNIAHRFITKLEQQG-KDVTVVTQNIDGLHQSAGNSKVLELHGNVQTNYCTHCKKVYQ-LEDSMGIPRCLHDG--HIIRPDIVMYGEALNVITEA
ITAIQNADMMIIAGTSLVVYPASTFVDF-FN-GETLAVINKTSLRTVR-SALIFEDYIGEVLNAIK-------------
>tr|G7MAR8|G7MAR8_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. DL-VIII GN=cobB PE=3 SV=1
--------------------------------------ESNNIVFFGGAGVSTESDIPDFRSSNGLFNEFTPEQLVSHTFYTKYPEE---FFKFYKSKLI
YPEAKPNSGHLALAKLEEMG-KLKAIVTQNIDGLHQMAGSKNVFELHGSIHRNYCVKCHEFYD-EKFLNGVPTCTKCG--GSVKPDVVLYEEGLDVIRGA
INAISKADTLIIGGTSLVVYPAAGLIDY-FK-GNNLILINKSSTSADS-KDLVIHDSIGKVLSEAV-------------
>tr|A0A069RD93|A0A069RD93_CLOLI NAD-dependent protein deacetylase OS=[Clostridium] litorale DSM 5388 GN=cobB PE=3 SV=1
--------------------------------------ESSNIVFFGGAGVSTESQIPDFRSGNGLYKTYPPEVMLSHSFFMSHTDE---FFEFYKSKMI
YGNAQPNMAHISLAKLEKLG-KLKAVITQNIDGLHQMAGSQNVLELHGSIHRNYCMGCNLFYD-LGYISNVPRCKKCG--AIVKPDVVLYEEGLDIVKSA
ISHIKECDLLIIGGTSLAVYPAAGLVEY-FS-GSGMVLINKTPTPFDY-KDLVISDPIGEVLGKAV-------------
>tr|T4VYU9|T4VYU9_CLOBI NAD-dependent protein deacetylase OS=[Clostridium] bifermentans ATCC 19299 GN=cobB PE=3 SV=1
--------------------------------------ESNNIVFFGGAGVSTASKIPDFRSSNGLFNELTPEQLVSHTFYLKYTKE---FFNFYKKKLI
YPDAKPNNAHIALAQLEKMG-KLKAIITQNIDGLHQMAGSKNVFELHGSVHRNYCVSCNEFYD-SNFLNDVPTCTKCG--HTVKPDVVLYEEGLDIIKGS
INAISKADTLIIGGTSLVVYPAAGLIDY-FK-GKNLILINKSTTPADN-KDLVINDSIDIVLFNAL-------------
>tr|R9SPC8|R9SPC8_9EURY NAD-dependent protein deacetylase OS=Methanobrevibacter sp. AbM4 GN=cobB PE=3 SV=1
--------------------------------------NSNNIVFFGGAGVSTESGILDFRSNNGIYNTASPEEIISHSYFIKNPEK---FYDYYRKNLI
FQDAKPNNCHIGLKKLEDLG-KLQAIITQNIDGLHQKAGSENVLELHGSIYRNFCMKCGRPYL-IDDVNGIPRC-KCG--GMIKPDVVLYEEPLNILSFA
VDYISTCDTLIVGGTSLVVNPAATLIQY-FK-GKDLVIINKDETPYDS-QDVLINDNIGDVFKELM-------------
>tr|R9JIZ5|R9JIZ5_9FIRM NAD-dependent protein deacetylase OS=Lachnospiraceae bacterium A4 GN=cobB PE=3 SV=1
--------------------------------------ESTKIVFFGGAGVSTESGIPDFRSVDGLYNQYPPETILSHTFYMKKPEE---FFRFYRDKML
CLDKQPNAAHKVLAKLEAQG-KLTAVVTQNIDGLHQAAGSRKVLELHGSVMRNYCETCHQAYG-VEEV-GVPRCT-CG--GRIKPDVVLYEEGLDTLQEA
VRVISEADMLIIGGTSLAVYPAAGLIDY-YQ-GSRLVLINRTPTQRDT-MNLVITGSIGEVFSQLD-------------
>tr|F7K801|F7K801_9FIRM NAD-dependent protein deacetylase OS=Lachnospiraceae bacterium 3_1_57FAA_CT1 GN=cobB PE=3 SV=1
--------------------------------------KTDNIVFFGGAGVSTESGIPDFRSVDGLYNQYPPETILSHTFYRRMPEE---FFRFYRDKML
CLDAQPNAAHRKLAQWEEEG-KLKAIVTQNIDGLHQKAGSRNVLELHGSVLRNYCECCHKFYD-AEYL-GVPKCS-CG--GSVKPDVVLYEEGLDTVTRA
VEYISKADVLIIGGTSLAVYPAAGLIDY-YR-GNKLVLVNKTPTPRDR-EDLVVQGSIGEIFSGL--------------
>tr|R9KQ13|R9KQ13_9FIRM NAD-dependent protein deacetylase OS=Lachnospiraceae bacterium COE1 GN=cobB PE=3 SV=1
--------------------------------------ESKKIVFFGGAGVSTESGIPDFRSVDGLYNQYPPETILSHTFYMKRPDE---FFRFYRDKML
FTDAKPNAAHAALAKLEEAG-KLTAVVTQNIDGLHQSAGSKKVLELHGSVLRNYCETCRKFYD-IDAL-GVPFCE-CG--GRIKPDVVLYEEGLDTLSES
VRAISEADMLIIGGTSLAVYPAAGLIDY-YH-GNKLVLINKTPTARDT-MNLVITDSIGEVFLQIK-------------
>tr|C0CNC5|C0CNC5_9FIRM NAD-dependent protein deacetylase OS=Blautia hydrogenotrophica DSM 10507 GN=cobB PE=3 SV=1
--------------------------------------THSNIVFFGGAGVSTESGIPDFRSVDGLYNQYPPETILSHTFFMRKPEE---FFRFYRDKML
CDTAKPNAAHQKLAMLEKAG-KLKAVITQNIDNLHQMAGSKKVLELHGSVHRNYCMRCGKAYD-FAYKNGTPKC-DCG--GIVKPDVVLYEEALNTLSEA
VMAISQAEVLIIGGTSLAVYPAASLIDY-YQ-GEHLVVINKSPTPRDR-YNLLIQQPIGRVFSQIT-------------
>tr|R7R6K1|R7R6K1_9FIRM NAD-dependent protein deacetylase OS=Roseburia sp. CAG:100 GN=cobB PE=3 SV=1
--------------------------------------NSDNIVFFGGAGVSTESGIPDFRSVDGIYHQYPPETILSHTFYMRRPEE---FFRFYRDKLI
YPDAKPNAAHKVLAQLEREG-RLKAVVTQNIDGLHQAAGSKKVLELHGSTLRNYCEKCHKFYG-IDVM-GIPTCD-CG--GRIKPDVVLYEEGLDILSEA
VRVISEADMLIIGGTSLAVYPAAGLIDY-YQ-GHKLVLINKSATARDS-MDLVITDSIGKVFAQIR-------------
>tr|A0A0B3VVJ0|A0A0B3VVJ0_9FIRM NAD-dependent protein deacetylase OS=Terrisporobacter othiniensis GN=cobB PE=3 SV=1
--------------------------------------SHNNIVFFGGAGVSTESNIPDFRSASGLFNEFTPEQLVSHTFFMRYPED---FFKFYKDKLI
YEDAKPNNAHIALAKLEYMG-KLNAIITQNIDGLHQMAGSRNVLELHGSVHRNYCTKCGKFYT-LEELNNVPYCDVCG--SIVKPNVVLYEEPLDVVNET
VNALSNADLLIIGGTSLVVYPAASFIDY-FN-GDSIVLINKSSTGYDT-KSVVINDSIGKVLSQVI-------------
>tr|G6BMJ8|G6BMJ8_PEPDI NAD-dependent protein deacetylase OS=Peptoclostridium difficile 050-P50-2011 GN=cobB PE=3 SV=1
--------------------------------------NHNNIVFFGGAGVSTESNIPDFRSSTGLFSQFTAEQLVSHTFFVRYPEE---FFEFYKDKLI
YPNAKPNNAHIALAKLEEMG-KLKAVITQNIDGLHQMAGSKNVLELHGSVHRNYCTKCGKFFD-LESLNNIPYCDNCG--SIVKPDVVLYEEALDVITKT
ISAISNADLLIIGGTSLAVYPAASFIDY-YK-GDYIALINKANTVYDK-SSLVINKPIGEVLYEAV-------------
>tr|A0A089HLU3|A0A089HLU3_PAEDU NAD-dependent protein deacetylase OS=Paenibacillus durus GN=cobB PE=3 SV=1
--------------------------------------ESSRIVFFGGAGTSTESGIPDFRSAAGLYLSYPPEQMLSYSFFISKPDI---FFDFYRGKML
HPDAQPNGAHQLLARLEQDG-RLSAVVTQNIDGLHQKAGSRRVLELHGSVHRNHCMSCSRYYG-LDATGTVPRCPECG--GIIKPDVVLYEEELDVLTDS
VQAIANADLLIIGGTSLTVQPAASLIQY-FQ-GKHTVLLNGEPTSYDS-RDLIITDRIGWAMDRIS-------------
>tr|A0A0A0IZ30|A0A0A0IZ30_CLOHA NAD-dependent protein deacetylase OS=Clostridium haemolyticum NCTC 8350 GN=cobB PE=3 SV=1
--------------------------------------TSSKIVFFGGAGVSTESNIPDFRSENGIYKTESPEVMLSHGFFMKHTED---FFNFYKAKMV
YKDAKPNDAHIALAKLEAKG-KLNAIITQNIDGLHQLAGSKNVLELHGSVLRNYCMKCGKSFN-LDYMNLVPYCDKCG--GIVKPDVVLYEEELNVMYNA
IKHIKEADTLIVGGTSLVVYPAAGLIQY-FN-GDNLVLINKAATPYDD-KNLVINNSIGKILKEVV-------------
>tr|A0A0L6Z8D8|A0A0L6Z8D8_9CLOT NAD-dependent protein deacetylase OS=Clostridium homopropionicum DSM 5847 GN=cobB_2 PE=3 SV=1
--------------------------------------SSSDIVFFGGAGVSTESNIPDFRSEAGLYKTYPPEVMLSHSFFMNKTED---FFDFYKAKMI
YKEAKPNDAHNALAELERRS-ILKAVITQNIDGLHQLAGSKNVLELHGSILRNFCMKCGKKFD-LDYVNVIPYCDKCN--GVVKPDVVLYEEALDVMNKA
VRHIQQADTLIVGGTSLVVYPAAGLLQY-FN-GKHLVLINKAATAYDN-KDLVISDSIGKVLKEAI-------------
>tr|A0Q3N5|A0Q3N5_CLONN NAD-dependent protein deacetylase OS=Clostridium novyi (strain NT) GN=cobB PE=3 SV=1
--------------------------------------ESSRIVFFGGAGVSTESKIPDFRSETGLYKTYSPEQMLSHSFFMKNTED---FFEFYKKKMV
YKDAKPNDAHIALAKLEEMG-KLTAVITQNIDGLHQMAGSKNVLELHGSILRNYCMKCGKSFD-LDYMNAIPYCDACG--KIVKPDVVLYEEELNVMYSA
IKHIKEADTLIVGGTSLVVYPAAGLIQY-FN-GKNLVLINKAETPYDD-KNLVIHDSIGKVLKEAL-------------
>tr|A9KPQ2|A9KPQ2_CLOPH NAD-dependent protein deacetylase OS=Clostridium phytofermentans (strain ATCC 700394 / DSM 18823 / ISDg) GN=cobB PE=3 SV=1
--------------------------------------ESNNIVFFGGAGVSTESGIPDFRSENGLYTTYSPEQLLSHSFFMRHTHD---FFAYYKSHMI
YKEAKPNPAHLALAKLEELG-KLSAVITQNIDSLHQVAGSQTVYELHGSSNRNYCMKCRKSFS-LDQMKTVPICTNCG--GVVKPDVVLYEEELKTIQKA
IDAILKADTMIVGGTSLVVWPAASLIEY-FQ-GKNLVLINKSETTYDT-MSLVIHDSIGEVLDSVI-------------
>tr|F3ZWA2|F3ZWA2_MAHA5 NAD-dependent protein deacetylase OS=Mahella australiensis (strain DSM 15567 / CIP 107919 / 50-1 BON) GN=cobB PE=3 SV=1
--------------------------------------TSNNIVAFTGAGVSTESNIPDFRSPNGLYNSYPPETIISRSFFMEHPDI---FFDFYKNQMV
YKEAQPNDCHKALARLEQLG-KLKAVITQNIDGLHQKAGSRIVLELHGTIHSNHCMNCGKFFD-LDY--GVPLCDKCG--GIVKPDVVLYEEPLDTLAEA
VRYISEADVMLVMGTSLVVYPAAGLIDY-YS-GDKLVLINKTSTSYDF-KNIVIHDSVGETMRSIM-------------
>tr|L7VJA7|L7VJA7_CLOSH NAD-dependent protein deacetylase OS=Clostridium stercorarium subsp. stercorarium (strain ATCC 35414 / DSM 8532 / NCIMB 11754) 
----------------------------------------ESIVVLTGAGASTESGIPDFRSNVGPPKKYPVEVLLSHTFFINNTEI---FYDYYMNNMV
YRDAKPNDCHKALAEMEKYC-NVLAVITQNIDGLHQDAGSSDVIELHGSTRRNYCMKCGKAFS-LDEFAPVPKCDECG--GIIKPDVVLYEEPLNDLTRA
MKLTVKADAMLVIGTSLVVYPAAGLLNY-YR-GDKLIIINMDPTPFDY-RRLVIHDSAGKVMRQIV-------------
>tr|C7RE86|C7RE86_ANAPD NAD-dependent protein deacetylase OS=Anaerococcus prevotii (strain ATCC 9321 / DSM 20548 / JCM 6508 / PC1) GN=cobB PE=3 SV=1
----------------------------------------NNIVFFGGAGVSTASGVPDFRSATGLYNRYSPEYMLSHEFFVDHPDE---FMAYCKNNLM
LEGIKPNKAHLALAKLEKMG-KLKGVITQNIDSLHQEAGSKNVIELHGNLRDYYCTKCGKSFD-LDYKGDVATCDACG--GIVRPDIVLYGEGLDNISYA
VNLIANADILIVGGTSLVVYPAAGLLDF-YK-GNKLVLINKDPTSRDA-RDYVIKGDISKIMDELV-------------
>tr|U2J0P9|U2J0P9_9FIRM NAD-dependent protein deacetylase OS=Peptostreptococcaceae bacterium oral taxon 113 str. W5053 GN=cobB PE=3 SV=1
----------------------------------------DNIVFFGGAGVSTASGIPDFRSATGLYNQYSPEYMLSHEFLERNPEE---FSHYYKEHLI
YPEAKPNKAHLALAKLERLG-KLKAVITQNIDSLHQMAGSKKVLELHGNLRDYYCTSCHKSYT-LEEMKGMSICDQCG--GFIRPDVVLYGESLNIMQKA
AEMISKCEVLIVAGTSLVVYPAASFLRY-YR-GNKLMIINRDHTSKDE-MDYVIHDDLNEVMDELV-------------
>tr|A0A095X411|A0A095X411_9FIRM NAD-dependent protein deacetylase OS=Anaerococcus lactolyticus S7-1-13 GN=cobB PE=3 SV=1
----------------------------------------NNIVFFGGAGVSTASGVPDFRSATGLYNRYSPEYMLSHKFFINHPDE---FMTYCKENLM
LDGIKPNKAHYALAKLEKMG-KLKAVITQNVDSLHQEAGSKNVIELHGNLRDYYCVNCHKNFD-LAYKKAEAHCDECG--GIVRPDIVLYGEGLDNISYA
VNLIAQADVLIVGGTSLVVYPAAGLIDF-YR-GNKLVLINKETTPRDG-IDYVIKGDIADIMDRLV-------------
>tr|H3NM93|H3NM93_9FIRM NAD-dependent protein deacetylase OS=Helcococcus kunzii ATCC 51366 GN=cobB PE=3 SV=1
----------------------------------------NNIVFFGGAGVSTESGIPDFRSSTGLYNRYSPEYMLSHDFLVEDVVG---FTKYYKENLI
VEDAKPNITHKVLAKLEKMG-KVKAVVTQNIDSLHHMAGSKNVYEIHGNLRDYYCVKCGKTYD-SDYLQEPNYC-DCG--GYIRPDVTLYGEGLPAVRNA
INAIAHADVLIIGGTSLVVYPAASFIDF-YR-GNKCILINKEQVGRNT-SNYVIMSSLGEVFRKID-------------
>tr|F0GZX7|F0GZX7_9FIRM NAD-dependent protein deacetylase OS=Anaerococcus hydrogenalis ACS-025-V-Sch4 GN=cobB PE=3 SV=1
----------------------------------------NNIVFFGGAGVSTASGVPDFRSATGLYNRYSPEYMLSHEFFVNHPDK---FMEYAKENLM
IEGIKPNDCHYALTKLEKMG-KLKGIITQNIDSLHQEAGSKNVIELHGNLRDYYCTSCGKNFD-LSYKKNLVTCDKCG--SVVRPDIVLYGESLNNINYA
VNLISQADVLIVGGTSLVVYPAAGLIDF-YR-GKKLVVINRDPTPKDN-KDYLLKGDISKIMKELV-------------
>tr|F0GTG2|F0GTG2_9FIRM NAD-dependent protein deacetylase OS=Anaerococcus prevotii ACS-065-V-Col13 GN=npdA PE=3 SV=1
----------------------------------------NNIVFFGGAGVSTASGVPDFRSATGLYNRYSPEYMLSHEFFVNHPDK---FMTYCKENLM
IDGIKPNACHYALAKLEKMG-KLKAVITQNIDSLHQEAGSKNVIELHGNLRDYYCTKCGKSFD-LSYKGTTATCDRCG--GVVRPDIVLYGEGLDNINYA
INLIANADVLIIGGTSLVVYPAAGLIDF-YN-GNKLVLINKDMTPQDS-RDYLINDDISKVMEELV-------------
>tr|C2CKA3|C2CKA3_9FIRM NAD-dependent protein deacetylase OS=Anaerococcus tetradius ATCC 35098 GN=cobB PE=3 SV=1
----------------------------------------NNIVFFGGAGVSTASGVPDFRSATGLYNRYSPEYMLSHEFFVNHPDK---FMTYCKENLM
LDGIKPNACHYALAKLEKMG-KLKAVITQNIDSLHQEAGSKNVIELHGNLRDYYCTSCGKAFD-LSYKADLVKCDSCG--GVVRPDIVLYGEGLDNISYA
INLIANADVLIVGGTSLVVYPAAGLLDF-YR-GNKLVLINQDPTSRDN-RDYVIKGDISKIMDELV-------------
>tr|B0S0T6|B0S0T6_FINM2 Transcriptional regulator Sir2 family OS=Finegoldia magna (strain ATCC 29328) GN=FMG_0296 PE=4 SV=1
----------------------------------------DKIVFFGGAGVSTASGIPDFRSATGLYNKFSPEYMLSHEFFVTHPDL---FQDYVLENLI
IDGVKPNNAHLSLRKLEKAN-KLLGVITQNIDSLDTMAGTKNIAEIHGNLRDYYCVNCGAKYD-LDYKQRPCKCEKCG--GVVRPDVTLYGEVPPEFAKA
INWINKADTMIVAGSSLVVYPASGLINY-FR-GDNLILINLDRTSYDN-MNIVIHDDIAKTLEYVT-------------
>tr|A0A0J1FZU3|A0A0J1FZU3_9FIRM NAD-dependent protein deacetylase OS=Robinsoniella sp. RHS GN=cobB PE=3 SV=1
--------------------------------------ESRNVVFFGGAGVSTESGIPDFRSVDGLYNQYPPETILSHTFFMRDPKE---FYRFYQNKML
CLDAKPNTAHRKLAQWEEEG-KLKAVITQNIDGLHQKAGSKEVLELHGSVHRNYCMKCKKPYD-AGYL-GIPSCE-CG--GIIKPDVVLYEEGLDIMSRA
ISYIAKADVLIVGGTSLAVYPAAGLIDY-YR-GNKLVLVNKTTTPMDH-NDLLVQGSIGEIFAAI--------------
>tr|R7F5S8|R7F5S8_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. CAG:354 GN=cobB PE=3 SV=1
--------------------------------------KSKSVVFFGGAGVSTESGIPDFRSKDGLYNQYPPEEILSHTFFINHTKE---FYEFYKDKMN
SLKYEPNITHIKLTELEQKG-ILKAIVTQNIDGLHQKAGSKNVLELHGSVHRNYCMKCGKFYD-AKYFNGVPKCI-CG--GIIKPDVVLYEEGLNILEEA
IYQISNCDILIVGGTSLTVYPASGLIRY-YS-GNNLILINKDATPFDN-VNLVIKDSLGNIFKNI--------------
>tr|R6BL89|R6BL89_9FIRM NAD-dependent protein deacetylase OS=Firmicutes bacterium CAG:56 GN=cobB PE=3 SV=1
--------------------------------------GSNNIVFFGGAGVSTESGIPDFRSTDGLYHQYPPETILSHSFFMRNPEE---FYRFYKNKML
CLDAKPNMAHKKLAELEKAG-KLKAVITQNIDGLHQAAGSKEVLELHGSVHRNYCMKCGKSYD-AEYL-GVPTCS-CG--GRIKPDVVLYEEGLDVMARA
IQAIQDADMLIIGGTSLIVYPAAGLIDY-YR-GNKLVVINMSVTSQDK-NDLVIQEPIGKVFAGI--------------
>tr|R8VTU4|R8VTU4_9CLOT NAD-dependent protein deacetylase OS=Butyricicoccus pullicaecorum 1.2 GN=cobB PE=3 SV=1
--------------------------------------QSDNIVFFGGAGVSTESGIPDFRSVDGLYNQYPPETILSHTFFMAQTEE---FYRFYRDKML
CLDAQPNAAHRKLAEWEQQG-KLRAVITQNIDGLHQKAGSKEVLELHGSVHRNYCMRCRKPYG-VEEA-GVPRCT-CG--GIIKPDVVLYEESLDTLDKS
LAYIQNADILIIGGTSLAVYPAASLIHY-YR-GKKLVLVNKTPTSADA-KNLVIHGAIGEIFSQL--------------
>tr|R9LVK9|R9LVK9_9FIRM NAD-dependent protein deacetylase OS=Anaerotruncus sp. G3(2012) GN=cobB PE=3 SV=1
--------------------------------------ESRRIVFFGGAGVSTESGIPDFRSVDGLYSQYPPETILSHTFFVRHTEA---FFEFYRAKML
CLDAEPNAAHHTLAALERAG-KLTAVVTQNIDGLHQAAGSKTVHELHGSVHRNYCMDCGRAYD-AAYL-GIPRC-TCG--GIIKPDVVLYEESLNTLEQS
VEAISSCDLLIIGGTSLAVYPAAGLVNY-CR-GK-IAVVNRSSTPLDA-KDLLVQGSIGETFSALA-------------
>tr|C6LLS9|C6LLS9_9FIRM NAD-dependent protein deacetylase OS=Marvinbryantia formatexigens DSM 14469 GN=cobB PE=3 SV=1
--------------------------------------ESNNVVFFGGAGVSTESGIPDFRSVDGLYNQYPPETIISHTFFLNRTEE---FYRFYKKKML
VLDAKPNMAHIRLAEWEKSG-HVRAVITQNIDGLHQMAGSKEVLELHGSVHRNYCQKCRKFYD-AEYKAGIPRCS-CG--GIIKPDVVLYEEGLDIMMKS
IRHIASADVLIIGGTSLVVYPAAGLIDY-FR-GSKLVVINRSTTSRDK-NDLVIDDSIGKVFESIH-------------
>tr|R7AZY5|R7AZY5_9FIRM NAD-dependent protein deacetylase OS=Ruminococcus sp. CAG:379 GN=cobB PE=3 SV=1
--------------------------------------QSSSIVFFGGAGVSTESGIPDFRSVDGLYN-YPPEEILSHRFFLNHTKE---FYTFYRKKIL
LCMPQPNAAHYKLAQLEQAG-RLRAVITQNIDGLHQKAGSKHVLELHGSVERNYCMDCGRAYS-ADY--DIPRC-NCG--GIIKPDVVLYEESLDVISQS
IAALQQADLLIVGGTSLNVYPAAGFLQY-FR-GNASVLINCGETQMDG-SDLLIRDKIGSVLNQIR-------------
>tr|F4XD40|F4XD40_9FIRM NAD-dependent protein deacetylase OS=Ruminococcaceae bacterium D16 GN=cobB PE=3 SV=1
--------------------------------------ESKNIVFFGGAGVSTESGIPDFRSVDGLYNQYPPETILSRSFFDRDPEE---FYRFYRNKML
CLTAKPNAAHKKLAQLEAAG-KLKSIVTQNIDGLHQAAGSKRVWELHGSVLRNRCMACGRDYS-VSAA-GVPRC-SCG--GIIKPDVVLYEESLSVLQGA
LSDIQQADMLIIGGTSLVVYPAAGLVNY-YQ-GHRLVLINKSTTPYDK-NDLVLSGPIGEILDQIK-------------
>tr|R5HZR7|R5HZR7_9FIRM NAD-dependent protein deacetylase OS=Ruminococcus sp. CAG:60 GN=cobB PE=3 SV=1
--------------------------------------KYDNIVFFGGAGVSTESGIPDFRSQDGLYNQYPPETILSHTFFMRHPDE---FYRFYQDKML
CDTAKPNAAHLKLAELEASG-KLKAVITQNIDNLHQMAGSKKVLELHGSVYRNYCMKCGKSYD-FAYKNGVPKC-TCG--GMIKPDVVLYEEGLDVISEA
VRAISQAQVLIIGGTSLAVYPAAGLIDY-FS-GEHLVVINKSPTPRDR-YDLLIKEPIGQVFSQIQ-------------
>tr|R7ECN1|R7ECN1_9FIRM NAD-dependent protein deacetylase OS=Roseburia sp. CAG:471 GN=cobB PE=3 SV=1
--------------------------------------QYDRIVFFGGAGVSTESGIPDFRSVDGLYNQYPPETILSHTFFMRHTDE---FYRFYRDKML
ALDAKPNDAHKKLAEMEEAG-KLTGVVTQNIDGLHQAAGSKHVMELHGSVHRNYCMKCHKFYD-ASYL-GVPKCE-CG--GVIKPDVVLYEEGLDVVSDA
IRTIAEAEVMIVGGTSLAVYPAAGLLDY-FR-GKALVLINKGATPQDR-NDLLIQKPIGQIFSQMK-------------
>tr|R5B178|R5B178_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. CAG:226 GN=cobB PE=3 SV=1
--------------------------------------SSKRIAFLGGAGVSTESGIPDFRSENGYFEAYPPEELLSHTFFMRHTDV---FYKYYRSALM
VTGIKPNRAHYALAKLERMG-KLTAVITQNIDGLHQLAGSRNVYELHGSIYRNHCMECGKSYT-VEQ--NVPIC-SCG--GVIKPDVVLYEEGLDTLRAA
ITHITRADMLIVGGTSLNVYPASGLIDY-YK-GNKLALINKSETPYDY-RDLIINDSIGMALDKAT-------------
>tr|A0A0M1KZU8|A0A0M1KZU8_CLOBO NAD-dependent protein deacetylase OS=Clostridium botulinum GN=cobB PE=3 SV=1
--------------------------------------NSENIVFLGGAGVSTESNIPDFRSNNGLYKSYSPETILSHSFFKNNAKE---FFQFYKDKMI
FKDAKPNLAHYALTELEQIG-KLKTIITQNIDGLHQLSGAKNVLELHGSVHRNYCVNCGEKYN-LDYLNDIPYCKKCG--SIVRPDVVLYEEGLDTISKA
IYYIQNADVLIVGGTSLVVYPAAGLVNY-YK-GKKLVLINKAETPYDK-KDLVIHDSIGSVLEKVI-------------
>tr|A0A0M1J0S9|A0A0M1J0S9_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. L74 GN=cobB PE=3 SV=1
--------------------------------------NSENIVFLGGAGVSTESNIPDFRSNNGLYKAYSPEAMLSHSFFKKHIEE---FFEFYKKQMI
YKNAKPNLAHHALAELEKMG-KLKAIITQNIDGLHQLAGSKNVLELHGSVHRNYCVDCNERYD-LEYLDDIPRCKKCG--GIVRPDIVLYEEGLDIVNKA
IYYVENADVFIVGGTSLVVYPAAGLVNY-YK-GKKLVLINKGETPYDK-GNLVIHDSIGTILEKSI-------------
>tr|W7YWV6|W7YWV6_9BACL NAD-dependent protein deacetylase OS=Paenibacillus pini JCM 16418 GN=cobB PE=3 SV=1
--------------------------------------QSNNIVFFGGAGTSTESGIPDFRSAAGLYQTYPPEVMLSHSFFVKMPDI---FFDFYRSKML
HPDAKPNGCHTLLARLEKEG-KLKAIVTQNIDGLHQKAGSHEVLELHGSIYRNYCMGCDHFYD-LEQMAMVPRCPRCR--GVIKPDVVLYEEPLDVLFRS
MEAISHADLLIIGGTSLTVHPAAELVSY-FE-GNRTVLLNMDPTPYDN-KDLLITERIGEFMMKTS-------------
>tr|A0A0M9BTW4|A0A0M9BTW4_9BACL NAD-dependent protein deacetylase OS=Paenibacillus sp. A59 GN=cobB PE=3 SV=1
--------------------------------------ESSNIVFFGGAGTSTESGIPDFRSAAGLYQTYPPEELLSRRFFDQHADI---FYDFYRGKML
HPDAAPNGCHRLLARLEQEG-RLQAVITQNIDGLHQKAGSSNVLELHGSIHRNACMDCKRFYA-LDDITTVPRCTACG--GVIKPDVVLYEEELDILYRS
VDALSSADLLLVGGTSLTVYPAAQLITY-FQ-GKHTVLLNATPTAYDR-RDLLITDPIGEVMNKVD-------------
>tr|A0A069DHV1|A0A069DHV1_9BACL NAD-dependent protein deacetylase OS=Paenibacillus sp. TCA20 GN=cobB PE=3 SV=1
--------------------------------------ESNKIVFFGGAGTSTESGIPDFRSAAGIYQTYSPEELLSIDFFMLHPDI---FYDFYRSKML
HPRAKPNGAHRLLARLEKEG-KLSAVITQNIDGLHQAAGCGKVHELHGSVHRNYCMDCAHFYD-LDAFALVPKCNKCN--GIIKPDVVLYGESLDTLYHA
VDALSEADLMIIGGTSLTVQPAAQLVTY-FQ-GRHTVLLNATPTPYDS-RDLLITEPIGRVLDQVN-------------
>tr|A0A0B0HWW5|A0A0B0HWW5_9BACL NAD-dependent protein deacetylase OS=Paenibacillus sp. P1XP2 GN=cobB PE=3 SV=1
--------------------------------------QSDNIVFFGGAGTSTESGIPDFRSAAGLYQTYPPEQMLSRSFFMKMPEI---FFDFYRSKML
HPDAKPNGCHRLLAKLEAQG-KLKAIVTQNIDGLHQQAGSEEVLELHGSVHRNYCMGCRRFFG-LEQMALVPRCPYCQ--GIVKPDVVLYEEALDVLISA
MDAIANADLLLIGGTSLTVHPAAELVSY-FK-GTRSVLLNMDPTPYDK-RDLIINDKIGEVMDQVG-------------
>tr|A0A0D3V638|A0A0D3V638_9BACL NAD-dependent protein deacetylase OS=Paenibacillus sp. IHBB 10380 GN=cobB PE=3 SV=1
--------------------------------------ESERIVFFGGAGTSTESGIPDFRSAAGLYQSYPPEEMLSHHFFVERPEV---FYDFYRTKMI
HKDAKPNTCHHLLATLEQRG-QLKSIITQNIDGLHQKAGSSRVLELHGSIHRNYCMGCAHFYD-LDTIELVPRCTSCN--SVIKPDVVLYEESLDILYEA
MEAISSADLIIVGGTSLTVQPAAQLVSY-YQ-GNRSVLLNIDATPYDH-RDLHISHKIGEVMDQVS-------------
>tr|E0RLP9|E0RLP9_PAEP6 NAD-dependent protein deacetylase OS=Paenibacillus polymyxa (strain E681) GN=cobB PE=3 SV=1
--------------------------------------QSQNVVFFGGAGTSTESGIPDFRSAAGLYQSYSPEVMLSRSFFVKHPEV---FFDFYRSKML
HPDAEPNGCHHFLASLEKQG-RLKAVVTQNIDGLHQAAGSMNVLELHGSVHRNHCMECGRYYS-LDEMNVVPKCPIDG--GIIKPDVVLYEEELNTLIQS
VQAISQADLLLIGGTSLTVHPAAGLITY-FR-GKHTVLLNTDPTSYDH-KDLLITDPIGKVMEKLA-------------
>tr|A0A0Q7SC68|A0A0Q7SC68_9BACL NAD-dependent deacetylase OS=Paenibacillus sp. Root52 GN=ASD24_14365 PE=4 SV=1
--------------------------------------ESKKIVFFGGAGTSTESGIPDFRSAAGLYQTYPPEELLSRHFFDQHADI---FYDFYRGKML
HPQAEPNGCHRLLARLENEG-RLQAVITQNIDGLHQKAGSKNVLELHGSVHRNACMDCKRFYS-LDDIRIVPRCISCG--GVVKPEVVLYEEELDTLYLS
VDAISTADLLLVGGTSLTVQPAAQLITY-FQ-GKHTVLLNATPTAYDR-QDLLITEPIGEVMNTVD-------------
>tr|R5FH76|R5FH76_9FIRM NAD-dependent protein deacetylase OS=Faecalibacterium sp. CAG:1138 GN=cobB PE=3 SV=1
--------------------------------------TSKNTVLFTGAGISCPSGIPDFRSADGLYNEYSPEQIISHSFFVAHPKE---FYEFYKSKMV
YPKAKPNAAHRYFAKLEEEG-KLSAIVTQNIDGLHQAAGSKNVLEFHGSVHRNHCMRCGKFFD-VNY--GAPKCDKCG--GLVKPDVVLYEEGIDVFEAS
VAAIENAQTVIVVGTSLAVYPAAGLLTG-FR-GENLVLVNKQATPFDR-YTLVFNEDVINVVKRLE-------------
>tr|G7VSV9|G7VSV9_PAETH NAD-dependent protein deacetylase OS=Paenibacillus terrae (strain HPL-003) GN=cobB PE=3 SV=1
--------------------------------------QSQNIVFFGGAGTSTESGIPDFRSAAGLYQSYPPEVMLSRSFFVKHPEV---FFGFYRSKML
HRDAEPNGCHRFLASLEQQG-RLKAVVTQNIDGLHQAAGSVNVLELHGSVHRNHCMECGRFYS-LNEMDVVPKCPEDG--GIIKPEVVLYEEELDTLVRS
IQAISQADLLLIGGTSLTVHPAAGLITY-FH-GKHTVLLNTDPTSYDH-KDLLITDPIARVMGELG-------------
>tr|A0A0C7SFK0|A0A0C7SFK0_CLOSO NAD-dependent protein deacetylase OS=Clostridium sordellii GN=npdA PE=3 SV=1
--------------------------------------ASNNIVFFGGAGTSTESGIPDFRSSNGLFNEFTPEQLVSHTFFVRYPED---FFKFYKDKLI
YKNAKPNKAHIALAKLEKCG-KLKAIITQNIDGLHQMAGSKNVFELHGSVHRNYCENCRKFYN-LDDLNIVPHCEECG--SIVKPDVVLYEEALDVVNKA
ISAISKADLLIIGGTSLVVYPAAGFINY-FK-GKNIVVINKDNIKLNK-NVLEINESIGEVLNKAI-------------
>tr|D4J684|D4J684_9FIRM NAD-dependent protein deacetylase OS=Coprococcus catus GD/7 GN=cobB PE=3 SV=1
--------------------------------------ASDNIVFFGGAGVSTESGIPDFRSETGIYNTCSPEQILSHTFFMRKPEI---FYDFYKSTMV
YREAEPNEAHKALAKLEKIG-KLKAVVTQNIDGLHQKAGSEKVYELHGTIMKNYCMKCGQFYD-LDYMAGVPRCEKCG--GMVKPDVVLYEEGLDTISKS
VRAIAEADVLIIGGTSLNVYPAAGFINY-YH-GNKLVLINKSETPYDH-ENLLIHDSIGKVLKACV-------------
>tr|R6XGM0|R6XGM0_9FIRM NAD-dependent deacetylase OS=Firmicutes bacterium CAG:345 GN=BN617_00498 PE=4 SV=1
----------------------------------------TNIVFFGGAGCSTESGIPDFRSAKGIYTNRSAEEIVSHSYFFQNPER---FYRFYKDKMM
FLDAKPNACHQYFAKLQET--KNVTIVTQNIDGLHQLAGSLKVYELHGSIHRNYCLKCDKFFD-ANYYDGVPYCDKCG--GMIKPDVVLYEEPLDVIYGA
IKAIENSDLLIVGGTSLNVYPAAGFIRY-YH-GVKLVNINLDDNHLTN-C-LNIKAPIAEVFKKIT-------------
>tr|R6E5Z6|R6E5Z6_9FIRM NAD-dependent protein deacetylase OS=Ruminococcus sp. CAG:563 GN=cobB PE=3 SV=1
----------------------------------------SKTVFFGGAGVSTESGVKDYRSEDGLYNTVSPETILSHSFFVSKPDV---FYDFYYKYFL
EINVEPNTAHIVLAEMEKKG-KLSSVITQNIDGLHQKAGSKNVIELHGTTAVHYCMECGKPYP-LEKKSKVPHCEKCG--GLVRPDVVLYEEPLKVVEKA
ISEISTADLLIIGGTSLAVYPAAMYIRY-FR-GSNIVLINKGKTDLDS-SDLVFRDSIGQLFGSIK-------------
>tr|D4YIE6|D4YIE6_9LACT Transcriptional regulator, Sir2 family OS=Aerococcus viridans ATCC 11563 GN=HMPREF0061_1635 PE=4 SV=1
----------------------------------------QRIVFFTGAGMSTASGIPDFRSANGLFMEYSPEEVVSHHFFTQYPKE---YFAYHFDKLV
YPEATPNIGHEFIASLEGSG-KDVSVVTQNIDGLHQKAGSSAVYELHGSTLDNYCVSCGHHYK-LEEQLGIPRCSIDQ--GIVRPNIVLYQEQLDVVNGA
VDKIRQADLLVILGTSLVVYPAAGFLNY-FR-GQYLTVVNKSPLQIPY-HALVFEDTIENVFSQLS-------------
>tr|A0A0H3IXL5|A0A0H3IXL5_CLOPA NAD-dependent protein deacetylase OS=Clostridium pasteurianum DSM 525 = ATCC 6013 GN=cobB1 PE=3 SV=1
--------------------------------------NSSNIVFFGGAGVSTESGIPDFRSSNGLFNQFTPEELVSHTSFMRYPED---FFDFYRDKLI
YQDAKPNAAHTSLMKLEKIG-KLKAIVTQNIDGLHQMAGSKNVYELHGSVHRNYCMKCHEFYD-VDFVKGIPKCSKCG--GTVKPDVVLYEESLNVINGA
VDAISKADTLIIGGTSLMVYPASGLIQY-FK-GKHLVLINKSSTSYDN-LEIVINDKIGETLKKIV-------------
>tr|D6GSE4|D6GSE4_FILAD NAD-dependent protein deacetylase OS=Filifactor alocis (strain ATCC 35896 / D40 B5) GN=cobB PE=3 SV=2
--------------------------------------NSNNIVFLGGAGVSTESNIPDFRSNTGLYNMFSAEEILSSPFFFEHTKE---FYEFYNDKMI
YKDAKPNNAHLALAKLEELG-KLKAIITQNIDGLHQLAGSRNVLELHGSVLHNHCTGCGKYYS-LDD--DIPFCKDCG--NIIKPDVTLYQEALNVFEKA
IYYIEHTDILIVGGTSLVVYPAASLVRY-YK-NNKLVLINRDETTYDS-MNLIFRDSIGDVLSRIV-------------
>tr|F2JHI4|F2JHI4_CELLD NAD-dependent protein deacetylase OS=Cellulosilyticum lentocellum (strain ATCC 49066 / DSM 5427 / NCIMB 11756 / RHM5) GN=cobB P
--------------------------------------DSNNIVFFGGAGVSTASQIPDFRSANGLFNEFTPEQLVSHTFFVKYPED---FYQFYKDKLI
YPEAQPNACHKALVKLEQMG-KLKAIVTQNIDGLHQMAGSQVVYELHGSVHRNYCLKCGAFYD-AAYLEGIPKCQRCG--GVVKPDVVLYEEGLDVISAA
VSAIAMAETLIIGGTSLVVYPAAGLIHY-FK-GKHLILINKSTTSADD-TDLVIHDAIDKVLAEAV-------------
>tr|R7FFS2|R7FFS2_9FIRM NAD-dependent protein deacetylase OS=Ruminococcus sp. CAG:330 GN=cobB PE=3 SV=1
--------------------------------------AAHRIVFFGGAGVSTESGIPDFRSQDGLYHQVPPETILSRTYFDRHPAE---FYRFYRNKMI
CLTAKPNAAHKKLAELEQAG-RLLAVVTQNIDGLHQMAGSRNVLELHGSVHRNICRSCGAVYD-AEWM-GIPHCDKCG--GMVKPDVVLYEESLSVLTRS
ISAIASADLLIVGGTSLVVYPAAGLLRY-FQ-GDSLVLINRDATQMDK-MDLCIRDAIGAVMEQIQ-------------
>tr|R7GSQ3|R7GSQ3_9FIRM NAD-dependent protein deacetylase OS=Ruminococcus sp. CAG:403 GN=cobB PE=3 SV=1
--------------------------------------NGTRMVFFGGAGVSTESGIPDFRSPDGLYHMVPPEQLLSHSYFYSHTKQ---FYQFYREKMI
CLTAKPNAAHRKLAELERAG-KLSAIVTQNIDGLHQAAGSQNVLELHGSVHRNDCLQCGARYD-AQWLEGIPHCEACG--GLIKPDVVLYEESLDILERS
IAAISQADVLMIGGTSLSVYPAAGLVRY-FQ-GDALVLLNRTPTQMDQ-QTLCISDPIAAVLEQIT-------------
>tr|U2M4B3|U2M4B3_9FIRM NAD-dependent protein deacetylase OS=Ruminococcus callidus ATCC 27760 GN=cobB PE=3 SV=1
--------------------------------------QSDRIVFFGGAGVSTESGIPDFRSQDGLYHQVPPETILSHTYFERHTAE---FYRFYRNKMI
CLTAKPNAAHKKLAELEQAG-KLLAVVTQNIDGLHQLAGSRSVLELHGSVHRNICQVCGAVYD-AEWM-GVPHCDKCG--GRVKPDVVLYEESLPTLTRS
VNAIANADLLLVGGTSLTVYPAAGLLRY-FR-GEHLVLLNRDATPMDE-QDLCIREPIGKVLEQIQ-------------
>sp|Q97MB4|NPD_CLOAB NAD-dependent protein deacetylase OS=Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787) 
--------------------------------------ESSSIVFFGGAGVSTESNIPDFRSENGLYKTYPPEVMLSHTFFKNHTED---FFEFYREKMI
FKDAKPNAAHYSLAKIEEQG-KLKAIVTQNIDGLHQLAGSKNVYELHGSIHRNYCMDCGKSFD-LEYIKTIPKCDKCG--GIVKPDVVLYEEGLDIIQNS
VKAISEADTLIVGGTSLVVYPAAGLIRY-FK-GNKLILINKSATAYDN-EDLVISDSIGKVLETVI-------------
>tr|A0A037Z2Z7|A0A037Z2Z7_CLOTT NAD-dependent protein deacetylase OS=Clostridium tetanomorphum DSM 665 GN=cobB PE=3 SV=1
--------------------------------------ESSNIVFFGGAGVSTESDIPDFRSQDGLYKTYPPEVMLSHSFFCEHTED---FFHFYKSKMI
YKNAKPNKAHYALGKLENMG-KVKAVITQNIDGLHQEAGSKEVIELHGSIHRNYCIDCGKFFD-LNYLHIVPKCDKCG--GIVKPDVVLYEEALNAINKA
INYVENADVLIIGGTSLVVYPAANLVHY-YN-GNKLILINKDSTSYDS-KSLVINDKIGEVLNQVI-------------
>tr|U6ES63|U6ES63_CLOTA NAD-dependent protein deacetylase OS=Clostridium tetani 12124569 GN=cobB PE=3 SV=1
--------------------------------------SSSNIVFFGGAGVSTESNIPDFRSEEGLYKTYSPEVMLSHSFFKEHTED---FFDFYKEKMI
YKYAKPNLAHHALAKLEKVG-KLKAIITQNIDGLHQLAGSKNVIELHGGVGRNYCMDCNKFFD-LNYLNVVPKCDVCG--GIVKPDVVLYEEPLNNINNA
VRYVENADVLIVGGTSLVVYPAANLIHY-YK-GNKLVLINKSSTPYDR-KQIVINDSIGSILGGIV-------------
>tr|R7BGA1|R7BGA1_9FIRM NAD-dependent protein deacetylase OS=Firmicutes bacterium CAG:882 GN=cobB PE=3 SV=1
--------------------------------------ESSYIVFFGGAGVSTESSIPDFRSTDGLYNQYPPETILSHSFFMQKPEA---FYEFYRDKMI
YKDARPNKAHYALAALEKCG-KLKAVITQNIDGLHQAAGSRAVYELHGTIMQNYCTRCGREYP-LEAT-GIPRCSVCN--GIIKPKVVFYEEGLDVVSGA
ISHIRKADLLIIGGTSLTVYPAAGLIRY-FA-GKHIVLINKSQTASDG-MDLIIRDPIGETLGAVI-------------
>tr|R7ESJ2|R7ESJ2_9FIRM NAD-dependent protein deacetylase OS=Anaerotruncus sp. CAG:390 GN=cobB PE=3 SV=1
--------------------------------------EAKNIVFFGGAGVSTGSGIPDFRGGDGLYGTEPPEELLSRRCLAVQPEK---FFGYYRTHMI
YPDAAPNGAHRALAELERRG-KLTAVVTQNIDGLHQAAGSVNVIELHGSVMRNYCVRCGRRYP-LAY--GVPRCEACG--ALVRPDVVLYGECLDAWSRA
EEAISAADVLIVGGTSLTVQPAASLVGL-YE-GDHLIIINKTPTPYDG-YETVIRDPIEDVLESVV-------------
>tr|R6PAG8|R6PAG8_9FIRM NAD-dependent protein deacetylase OS=Eubacterium sp. CAG:274 GN=cobB PE=3 SV=1
--------------------------------------ESNNIVFFGGAGVSTESHIPDFRSEDGLYKAYSPETLISHSFFQRHTDK---FYEYYKENLI
YLDAKPNDAHYALAKLEEMG-KLKAVVTQNIDNLHQMAGSKTVYELHGSVFRNYCTKCHKFYD-VNEMAGVPYCE-CG--GVIKPDVVLYEEPLDVWQKA
FKAVREADMLIVGGTSLVVYPAAGLVDI-YK-GDKLVLINKSHTSYDH-LKIAINDSIGKVLKSVV-------------
>tr|R6ENB2|R6ENB2_9FIRM NAD-dependent protein deacetylase OS=Firmicutes bacterium CAG:238 GN=cobB PE=3 SV=1
--------------------------------------NSSNVVFFGGAGVSTESNIPDFRSEKGLYNARSPEEMLSHSFFMQQPDT---FFDYYKKNLI
YRDAQPNNAHKALAYLEKEG-RLKAVITQNIDGLHQKAGSKKVYELHGSVLRNHCMDCGEFYD-TDFMDNIPICPKCG--GIIKPDVVLYEEALDCMMGA
INAIEKADTMIIGGTSLVVYPAAGLIRY-FC-GKKLVLINKQPTPYDG-KDLVINDAIGKVMEVE--------------
>tr|A0A095XCQ6|A0A095XCQ6_9FIRM NAD-dependent protein deacetylase OS=Tissierellia bacterium S7-1-4 GN=cobB PE=3 SV=1
--------------------------------------ESKNIVFFGGAGVSTESGIPDFRSSNGVFSKLAPEQVVSHTYYKKIPKE---FFEFYFNNMV
FPEAKPNAAHIALAKLEAEG-KVKAVVTQNIDGLHQIAGSKTVYELHGSVHRNYCEKCHKFYS-LEDLKGIPICD-CG--GVIKPDVVLYEEALPMMFGA
IDSISKADTLIIGGTSLVVYPAASFINY-FR-GKHLVVINMTPTIADR-DDLVIDERIGEVFKKVM-------------
>tr|R5Y3R8|R5Y3R8_9CLOT NAD-dependent protein deacetylase OS=Clostridium bartlettii CAG:1329 GN=cobB PE=3 SV=1
--------------------------------------KSNNIVFFGGAGVSTESNIPDFRSSSGLFSEFTPEQLVSHTFFVRYPDE---FFKFYKDKLI
YKDAKPNNAHKALAKLEEIG-KLKAVVTQNIDGLHQMAGSKTVYELHGSVHRNYCTKCHKFFD-LDSLANIPHCDKCG--GVVKPDVVLYEEGLDTIEGA
IRAISSADLLIIGGTSLVVYPAASFINY-YR-GKDMVLINKSSTGYDN-DSLVINDAIGEVLKEAV-------------
>tr|U2QDV4|U2QDV4_9ACTN NAD-dependent protein deacetylase OS=Propionibacterium acidifaciens F0233 GN=cobB PE=3 SV=1
--------------------------------------GASRAVFFGGAGVSTESGIPDFRSATGLYTTYPPEYMLSHSCWRDRPED---FYEFYRATML
HPEARPNAAHTALARLEAAG-RLAAVVTQNIDGLHQMAGSRTVHEVHGSVLRNHCTGCGRSYP-VEA--GVPRCDDCG--GIIKPEVVLYEEGLDVMAAA
VEAIGRADVLIVGGTSLNVYPAAGLLDY-FR-GEPLVLVNKSATPADR-RDLVVHDSIGAVLGAAT-------------
>tr|A0A0A8PIU7|A0A0A8PIU7_9ACTN NAD-dependent protein deacetylase OS=Propionibacterium freudenreichii GN=npdA PE=3 SV=1
--------------------------------------PADHVVFFGGAGVSTESGIPDFRSATGLYKTFPPEYMLSHSCWADHPED---FYAFYRENML
HPEAKPNAAHYALARLEKAG-RLTAVVTQNIDGLHQMAGSKRVYELHGSVLRNHCVDCHRSYP-VEV--GIPRCTVCN--GIIKPDVVLYEEGLDVMDGA
TRAIMAADVLIVGGTSLNVYPAAGLLEY-YR-GDKLVLINKSATPADN-RQLVIHDSIGKVLGQAV-------------
>tr|A0A095XX96|A0A095XX96_9FIRM NAD-dependent protein deacetylase OS=Peptostreptococcus sp. MV1 GN=cobB PE=3 SV=1
--------------------------------------DSNNIVFFGGAGVSTESNIPDFRSSDGLFSKFSPEQLVSHTFFVHYPED---FYKFYRENLI
YRDAKPNKPHIALADLEKKG-KLKAIVTQNIDGLHQMAGSKNVFELHGSVNSNTCLSCGYNMD-LEELGIVAKCPKCG--GSVKPDVVLYEESLNTIRGA
IRAISQADMLIVGGTSLVVYPAAGFLDY-FK-GKYIVLINKAETGFDK-RDLVINDSIGKVLSSLV-------------
>tr|V9W4E9|V9W4E9_9BACL Cobyrinic acid A,C-diamide synthase OS=Paenibacillus larvae subsp. larvae DSM 25430 GN=cobB1 PE=4 SV=1
--------------------------------------EGERIVFFGGAGTSTESGIPDFRSAAGLYQKYPPEVMLSRSFFQKHTEE---FYSFYYEAML
HPDACPNAAHLTLAKLEEAG-KLSAIITQNIDGLHQKAGSKCVLELHGSVHLNTCLDCGRIYG-LEHLEKVPVCKDCG--GIVKPDVVLYEDSLDVIEQA
ALELSRADVVIVGGTSLTVQPAASLIQA-YT-GPNLVLMNRTPTHMDH-LKLVLREPMGELFSALT-------------
>tr|A0A0D5NFJ0|A0A0D5NFJ0_9BACL NAD-dependent protein deacetylase OS=Paenibacillus beijingensis GN=cobB PE=3 SV=1
--------------------------------------DSGNIVFFGGAGTSTESDIPDFRSAGGLYGSYPPEVMLSRTFFMQHTEQ---FYEFYRAKMV
HPHAKPGAAHLALTELERQG-KLRAVITQNIDGLHQKAGSRNVLELHGSVERNTCMECGARFE-LDYLQAVPKCGACG--GTVKPDVVLYEEMLDTLLKA
QEAVREADILIVGGTSLSVYPAAGLVAE-YE-GDKLILINKSATPYDA-RNYLIQDSIGKVLTALI-------------
>tr|A0A089KV07|A0A089KV07_9BACL NAD-dependent protein deacetylase OS=Paenibacillus sp. FSL R7-0331 GN=cobB PE=3 SV=1
--------------------------------------NSGNIVFFGGAGTSTESGIPDFRSAAGLYQSYPPEVMLSRRFFMSSPDI---FFDFYRSKML
HPEASPNGAHRLLAELEGQG-KLKAVITQNIDGLHQQAGSRAVFELHGSIHRNHCMGCGRFYP-VEATGSVPRCKDCG--GIIKPDVVLYEEELDVLVGS
VAAIAAADLLIIGGTSLTVQPAASLITY-FN-GRHTVLLNGESTPYDH-RDLIITDRIGEVMGRIM-------------
>tr|A0A089I1H5|A0A089I1H5_9BACL NAD-dependent protein deacetylase OS=Paenibacillus sp. FSL H7-0357 GN=cobB PE=3 SV=1
--------------------------------------DSGNIVFFGGAGTSTESGIPDFRSAAGLYQTYPPEVMLSRSFFMSSPDI---FFDFYRSKMI
HPEAEPNGAHLLLAELERQG-KLKAVITQNIDGLHQLAGSRVVLELHGSIHRNHCMGCNRYYG-LEQIQRAPLCPECG--GIIKPDVVLYEEQLDVLVGA
VAAIAAADLLIIGGTSLTVQPAASLVTY-FR-GRHTVLLNRDPTPYDH-RDLIITDRIGKVMGAVQ-------------
>tr|A0A089M8L7|A0A089M8L7_9BACL NAD-dependent protein deacetylase OS=Paenibacillus graminis GN=cobB PE=3 SV=1
--------------------------------------DSGSIVFFGGAGTSTESGIPDFRSAAGLYQTYPPEVMLSRSFFMSSPDI---FFDFYRSKMI
HPEAKPNGAHQLLAQLERDG-KLKAVITQNIDGLHQLAGSRRVLELHGSIHRNHCMDCSRYYG-LDQLAGVPRCPECG--GIIKPDVVLYEEELDVLVES
VAAIAAADLLIIGGTSLTVQPAASLITY-FR-GRHTVLLNGDPTPYDH-QDLIITDRIGAVMGKIQ-------------
>tr|A0A089KPA9|A0A089KPA9_9BACL NAD-dependent protein deacetylase OS=Paenibacillus sp. FSL R5-0345 GN=cobB PE=3 SV=1
--------------------------------------DCDNIVFFGGAGTSTESGIPDFRSAAGLYQTYPPEVMLSRTFFMSSPDI---FFDFYRSKMI
HPDARPNGAHQLLAELERQG-KLKAVITQNIDGLHQLAGSQKVLELHGSIHRNHCMDCSRYYG-LEQLSIVPRCPECG--GIIKPDVVLYEEELDVLVNS
VEAIAAADMLMIGGTSLTVQPAASLVTY-FR-GKRTVLLNGDPTPYDD-RDLLITDRIGKVLGSVK-------------
>tr|W4EBH1|W4EBH1_9BACL NAD-dependent protein deacetylase OS=Paenibacillus sp. FSL R7-277 GN=cobB PE=3 SV=1
--------------------------------------KSNNIVFFGGAGTSTESGIPDFRSAAGLYQTYPPEVMLSRSFFMSSPDI---FFDFYRSKMI
HPGAKPNGAHRLLAELEESG-RLKAVITQNIDGLHQIAGSRRVLELHGSIHRNHCMGCQRYYG-LEELESVPRCEDCG--GIIKPDVVLYEEALDVLVEA
VDAIAAADLLIIGGTSLTVHPAASLVTY-FR-GQHTVLLNGEPTPYDD-QDLIITERIGEVLGRVQ-------------
>tr|X4ZW70|X4ZW70_9BACL NAD-dependent protein deacetylase OS=Paenibacillus sabinae T27 GN=cobB PE=3 SV=1
--------------------------------------ESRSIVFFGGAGTSTESGIPDFRSAAGLYLTYPPEQMLSHSFFISKPDV---FFDFYRTKML
HPGAEPNGAHRLLARLESEG-RLSAVVTQNIDGLHQKAGSRSVLELHGSVHRNHCMNCSRYYG-LDATSTVPRCPACG--GIIKPDVVLYEEQLDVLNDS
VQAIASADLLLIGGTSLTVQPAASLIQF-FR-GKHTVLLNGESTPYDS-RDLIIKDRIGQAMERIG-------------
>tr|A0A098M7R1|A0A098M7R1_9BACL NAD-dependent protein deacetylase OS=Paenibacillus wynnii GN=cobB PE=3 SV=1
--------------------------------------SSDNIVFFGGAGTSTESGIPDFRSAAGLYQTYPPEVMLSRTFFMSSPDI---FFDFYRSKMI
HSEADPNGSHYLLAKLEQEG-KLKAVITQNIDGLHQKAGSQRVLELHGSIHRNHCMGCSRYFG-LDSINTVPRCPDCG--GIIKPDVVLYEEELDLLMEA
VEAIANADLLIIGGTSLTVQPAASLVTY-FR-GQHTVLLNGEPTPYDH-HDLILTDRIGETMSKVK-------------
>tr|A0A089LQJ3|A0A089LQJ3_9BACL NAD-dependent protein deacetylase OS=Paenibacillus stellifer GN=cobB PE=3 SV=1
--------------------------------------ESSSIVFFGGAGTSTESGIPDFRSAAGLYLTYPPEQMLSHSFFISKPEV---FFDFYRSKML
HPGAEPNGAHKLLARLEHEG-RLSAIVTQNIDGLHQKAGSTRVLELHGSVHRNHCMKCSRPYG-LETLETVPHCPVCG--GVIKPDVVLYEEELDVLTDS
IQALSSADLLIIGGTSLTVQPAASLTAY-FR-GRHAVMLNAEPTAYDS-RDLIITDRIGHVFERVG-------------
>tr|R9CG61|R9CG61_9CLOT NAD-dependent protein deacetylase OS=Clostridium sartagoforme AAU1 GN=cobB PE=3 SV=1
--------------------------------------ESDNIVFFGGAGVSTESGIPDFRSSNGLFNEFTPEQLVSHSFYIRYPEE---FFNFYKAKLI
YPEARPNKAHIALAKLEEMG-KLKAVITQNIDGLHQEAGSKNVFELHGSVLRNYCISCNAFYD-EKFLEGVPTCTKCG--GRVKPDVVLYEEGLDTIRGA
IEAISKADTLIIGGTSLVVYPAAGLINY-FR-GKNLILINKSTTSADN-KNLVIHDSIGKVLEEAV-------------
>tr|S6EHQ6|S6EHQ6_9CLOT NAD-dependent protein deacetylase OS=Clostridium chauvoei JF4335 GN=cobB PE=3 SV=1
-------------------------------------------MFFGGAGVSTASGIPDFRSSNGLFNEFTPEQLVSHSFYIRYPKE---FFNFYKAKLI
YPNAKPNGAHIALAKLEEMG-KLKAVITQNIDGLHQAAGSKKVFELHGSVHRNYCVKCNSSYD-VDFLEDVPTCTKCG--GTIKPDVVLYEEGLDTIRMS
IDAISKADTLIIGGTSLVVYPAAGLIDY-FR-GKNLVLINKSTTSADN-KNLVINDSIDKVLSSAL-------------
>sp|Q8XNS6|NPD_CLOPE NAD-dependent protein deacetylase OS=Clostridium perfringens (strain 13 / Type A) GN=cobB PE=3 SV=1
--------------------------------------NSNNIVFFGGAGVSTESGIPDFRSANGLFNEFTPEQLVSHSFFERYPEE---FFNFYKAKLI
YPNSKPNDAHIALAKLEEMG-KLKAIVTQNIDGLHQMAGSKNVFELHGSVLRNYCVDCHTFYD-EKFLEGVPKCTKCG--GIVKPDVVLYEEPLDVIRGA
IDAISKADTLIIGGTSLVVYPAAGLINYYFR-GKNLVLINKSSTQADS-KDLVINDSIGKVLGKVI-------------
>tr|R6KNH2|R6KNH2_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. CAG:265 GN=cobB PE=3 SV=1
--------------------------------------DSNNIAFFGGAGVSTESGIPDFRSSNGLYSEFTPEQLVSHSFYIRYPEE---FFNFYKAKLI
YPEAKPNDAHRALAKLEEIG-KLKAVITQNIDGLHQAAGSKVVYELHGSVLRNYCTRCHAFYD-EKFLKGVPTCTKCG--GNIKPDVVLYEEGLDVISGA
IAAISKADTLIIGGTSLVVYPAAGLINY-FR-GKNLVLINKSSTSADN-KDLVIHEAIGKVLGETV-------------
>tr|A0A0M0ACZ2|A0A0M0ACZ2_CLOBO NAD-dependent protein deacetylase OS=Clostridium botulinum GN=cobB PE=3 SV=1
--------------------------------------NSNNIVFFGGAGMSTESGIPDFRSANGLFNKFTPEQLVSHSFYIRHPEE---FFNFYKAKLI
YPDAKPNSGHIALAKLEEMG-KLKAIVTQNIDGLHQAAGSKNVFELHGSVHRNYCTNCNAFYD-SDFLEGIPTCTKCE--GTVKPDVVLYEEGLDTITGA
IKAISKADTLIIGGTSLVVYPAAGLIDY-FR-GKNLILINKSSTSADS-KNLVINDSVGKVLSEAV-------------
>tr|A0A0A6PXZ9|A0A0A6PXZ9_CLOBU NAD-dependent protein deacetylase OS=Clostridium butyricum GN=cobB PE=3 SV=1
--------------------------------------ESNNIVFFGGAGVSTESNIPDFRSSNGLWNEFTPEQLVSHTFFMKYPEE---FFRFYKNKLI
YPDAKPNAAHIALAKLEEMG-KLKAVVTQNIDGLHQAAGSKNVFELHGSVLRNYCMDCNAFYD-EKFLAGIPTCPKCS--GKVKPDVVLYEEGLDTIQGS
IAAISQADTLIIGGTSLIVYPAAGLINY-FR-GKNLILINKSTTSADS-KDLVIHEAIGKVLDKAV-------------
>tr|W6RXM7|W6RXM7_9CLOT NAD-dependent protein deacetylase OS=Clostridium bornimense GN=cobB3 PE=3 SV=1
--------------------------------------ESNNIVFFGGAGVSTESNIPDFRSSNGLWNEFTPEQLVSHTFFVRYPEE---FFKFYKDKLI
YPDAKPNAAHIALAKLEEMG-KLKAVVTQNIDGLHQAAGSKKVYELHGSVLRNYCMKCNAFYD-KKFLEGVPTCPKCG--GKVKPDVVLYEEGLDVISGA
VKAISEADTLIIGGTSLIVYPAAGLIDY-FR-GKNLVLINKSTTSADN-KDLVIHDAIGKVLGEAV-------------
>tr|N9Y7I9|N9Y7I9_9CLOT NAD-dependent protein deacetylase OS=Clostridium colicanis 209318 GN=cobB PE=3 SV=1
--------------------------------------ESNNIIFFGGAGVSTESNIPDFRSATGLFNEFTPEQLVSHSFYVRYPEE---FFNFYKAKLI
YPEAKPNLSHIALAKLEKMG-KLKAVVTQNIDGLHQAAGSKNVFELHGSVHRNYCTKCGQFYD-VDFLKGAPICTNCG--CQVKPDVVLYEEGLDVINGA
VRAISQADTLIIGGTSLVVYPAAGLIDY-FR-GKNLVLINKSKTSADS-KDLVINDSIGKVLDEAI-------------
>tr|A0A084JA09|A0A084JA09_9CLOT NAD-dependent protein deacetylase OS=Clostridium sulfidigenes GN=cobB PE=3 SV=1
--------------------------------------NSNNIVFFGGAGVSTESNIPDFRSANGLFNALSPEQLVSHTYFIRFPEE---FFNFYKAKLI
YPEAKPNGAHITLANLEEMG-KLKAIITQNIDGLHQAAGSKNVFELHGSIHRNYCIKCNDSYD-MDFLNGIPTCPKCS--GTVRPDVVLYEEGLDVLKGA
IDAISKADTLIIGGTSLVVYPAANLINY-FK-GKNLVLINKSSTSADS-RDLVIHDSIGKVLSESV-------------
>tr|L1QLV4|L1QLV4_9CLOT NAD-dependent protein deacetylase OS=Clostridium celatum DSM 1785 GN=cobB PE=3 SV=1
--------------------------------------ESNNIVFFGGAGVSTESGIPDFRSSNGLFNEFTPEQLVSHSFYIRYPEE---FFNFYKAKLI
YPEAKPNKAHLALAKLEKMG-KLKAVITQNIDGLHQAAGSKNVFELHGSVLRNYCVKCHAFYD-EKFLEGVPTCTKCG--GRVKPDVVLYEEGLDTIRGA
VNAIANADTLIIGGTSLVVYPAAGLIDY-FR-GKNLVLINKTSTSADS-KDLVINDSIGKVLDKAI-------------
>tr|A0A0F4VUU2|A0A0F4VUU2_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. IBUN22A GN=cobB PE=3 SV=1
--------------------------------------KSNNIVFFGGAGCSCESGIPDFRSSNGLWNELTPEQLVSHTMFMRYPEE---FFEFYRDKLI
YPEAEPNTAHIALAKLEGMG-KLKAIVTQNIDGLHQAAGSKNVFELHGSVLRNYCLSCNAFYD-EKFLEGIPTCPRCG--GKVKPDVVLYEEGLDVITGA
VRAISQADTLIIGGTSLVVYPAAGLIDY-FK-GKNLVLINKSSTSADN-KDLVIHDAIGKVLGEAV-------------
>tr|R6GJP0|R6GJP0_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. CAG:221 GN=cobB PE=3 SV=1
--------------------------------------DSNNIVFFGGAGCSCESGIPDFRSASGLWNELTPEQLVSHTMFMKYPKE---FFEFYRDKLI
YPDAKPNAAHIALAKLEEMG-KLKAVVTQNIDGLHQAAGSKHVYELHGSVLRNYCVKCHAFYD-EKFLEGVPTCTKCG--GNVKPDVVLYEEGLDVIKGA
IAAISKADTLIIGGTSLVVYPAAGLINY-FR-GKNLVLINKSSTSADN-KDLVIHEAIGKVLGETV-------------
>tr|K6SWG3|K6SWG3_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. Maddingley MBC34-26 GN=cobB PE=3 SV=1
--------------------------------------ESDNIVFFGGAGISTESNIPDFRSSNGLFNEFTPEQLVSHSFYIKYPEE---FFKFYKSKLI
YPEAKPNNGHLSLAKLEKMG-KLKAIVTQNIDGLHQMAGSKNVFELHGSVHRNYCVKCHAFYD-AKFLEDVPTCTECG--GAVKPDVVLYEEGLDVIRGS
IDAISKADTLIIGGTSLIVYPAAGLINY-FR-GKNLVLINKSSTSADS-KDLVINDSFGKVLSNAL-------------
>tr|D6DG85|D6DG85_CLOSC NAD-dependent protein deacetylase OS=[Clostridium] cf. saccharolyticum K10 GN=cobB PE=3 SV=1
--------------------------------------ESENVVFFGGAGVSTESGIPDFRSVDGLYSQYPPETILSHSFYIRKPEE---FFRFYRNKML
FPDAKPNRAHLALAKLEREG-KVKAVITQNIDGLHQAAGSREVLELHGSVHRNYCERCKTFYS-IEQMAGVPKCS-CG--GTIKPDVVLYEEGLDVLSRS
IQHIRNADMLIIGGTSLVVYPAAGLIDY-YR-GNRLVLINKSATARDS-QDLVICGSIGEVLGEAA-------------
>tr|A0A0D0RGU5|A0A0D0RGU5_9FIRM NAD-dependent protein deacetylase OS=Lachnospiraceae bacterium TWA4 GN=cobB PE=3 SV=1
--------------------------------------ESENIVFFGGAGVSTESKIPDFRSVDGLYNQYPPETILSHSFFMRNPKE---FFRFYRNKML
FPDAMPNKAHIALAKLEQEG-KLKAVVTQNIDGLHQKAGSKEVLELHGSVHRNYCMKCGKFYG-LDELSGVPTCS-CG--GIIKPDVVLYEEGLDVIEKS
LNYIARADILIIGGTSLSVYPAAGFVDY-YR-GNRLVLINKSATPMDS-RNLVINDPIGEVLGELL-------------
>tr|R5DT31|R5DT31_9FIRM NAD-dependent protein deacetylase OS=Eubacterium sp. CAG:86 GN=cobB PE=3 SV=1
--------------------------------------NSDNIVFFGGAGVSTESGIPDFRSVDGLYNQYPPETILSHSFYIRKPEE---FFEFYRNKML
FPDAEPSTTHIKLAELEKSG-KLKGVITQNIDGLHQKAGSSHVIELHGSELRNYCERCGKFYG-IDAI-GVPKCS-CG--GRIKPDVVLYEEGLDNIQEA
VRLIKEADVLIVGGTSLGVYPAAGLIDY-YN-GNKLVLINKSETPYDR-RDLLIHDALGNVFSQI--------------
>tr|R9MA81|R9MA81_9FIRM NAD-dependent protein deacetylase OS=Oscillibacter sp. 1-3 GN=cobB PE=3 SV=1
--------------------------------------GARSIVFFGGAGVSTESGIPDFRSTGGLYHQYPPEVILSHSFYKSNPEE---FFRFYRAKLL
APEARPNAAHRKLAEWERQG-KLAAVVTQNIDGLHQAAGSRRVYELHGSVHRNYCEKCRKFYD-FDFL-DAVPR-CCG--GTVKPDVVLYEEGLDTLNGA
VRAIAAADLLVIGGTSLNVYPAAGLINY-YR-GQRLALINKSAVARDL-DGLVIADPIGEVLGQL--------------
>tr|F7NIY0|F7NIY0_9FIRM NAD-dependent protein deacetylase OS=Acetonema longum DSM 6540 GN=cobB PE=3 SV=1
--------------------------------------GSDNIVFFGGAGVSTESGIPDFRSVDGLYSQYPPEVMLSHSFYVSHTDE---FYAFYKAKLL
APGAKPNKAHIRLAEWERTG-KVKAVITQNIDGLHQAAGSKTVLELHGSVKRNYCSRCKAFYD-EQFI-GVPTCS-CG--GTVKPDVVLYEEGLDIMQQA
TAFIANADVLIVAGTSLVVYPAAGLIDY-YR-GNKLVLINRAPTSADG-KDLLIQGSVGEVLGMVS-------------
>tr|R6ZUL4|R6ZUL4_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. CAG:299 GN=cobB PE=3 SV=1
--------------------------------------ESRNVVFFGGAGVSTESGIPDFRSVDGLYNQYPPETILSHTFYLRKTEE---FYRFYRNKML
FPEVKPNRAHLALARLEQEG-KVRAVITQNIDGLHQAAGSREVLELHGSVHRNYCERCGQFYS-MEHLSGVPKCS-CG--GVIKPDVVLYEEGLDVLSRS
IEHIRNADVLIIGGTSLTVYPAAGLIDY-YR-GTKLVLINKSATSRDS-QDLVICGSVGEALAEAA-------------
>tr|V1CNI1|V1CNI1_9FIRM NAD-dependent protein deacetylase OS=Eubacterium brachy ATCC 33089 GN=cobB PE=3 SV=1
--------------------------------------GDGRVVFFGGAGVSTESGIPDFRSEQGLYKAYSPEEILSHSFFMRNEEI---FFDYYKKNLI
YNNAKPNKAHLGLAKLEENG-KLSAVITQNIDGLHQLAGSKNVYELHGSILRNSCMQCDAKYD-LAYMDTVPKCEKCG--STVKPDVVLFEEALDQITNG
IREISAADTLIVGGTSLVVYPAAGLISY-FK-GKNLILINRDETPYDS-RNLVIHEKIGKVFEEII-------------
>tr|C7GZ45|C7GZ45_9FIRM NAD-dependent protein deacetylase OS=Eubacterium saphenum ATCC 49989 GN=cobB PE=3 SV=1
--------------------------------------KSNYVVFFGGAGVSTESGIPDFRSSDGLYNVAPPEKIISHSFFVADTNT---FFDYYKKHMV
YRDAMPGAAHLKLAELEKDG-KLKAVITQNIDGLHQLAGSKNVIELHGSILRNTCMKCGAKYS-LDYMDKVPKCSDCR--GIVKPDVVLYEEGLDVITEA
VNQISNADLLIVGGTSLVVNPAASLIQY-FK-GDELVLINKDETPYDF-KTKIYRKPIGEVLC----------------
>tr|B6FZB0|B6FZB0_9FIRM NAD-dependent protein deacetylase OS=[Clostridium] hiranonis DSM 13275 GN=cobB PE=3 SV=1
--------------------------------------SHNNIVFFGGAGVSTESNIPDFRSSNGLFNQFTPEEVVSYSFFVRYPEY---FYEFYKDKLI
YQDAEPNNAHKALAYLEEIG-KLKAVITQNIDGLHQKAGSKNVFELHGSVQRNYCTKCHKFFD-LEDLETIPKCDVCG--GIVKPDVVLYEEALDTINGA
VKAIKNADLLIIGGTSLVVYPAASFINY-YR-GKDLVLINKSSTSMDG-KTLKINAPIGKILYDTV-------------
>tr|A0A084U2L2|A0A084U2L2_MYCIO NAD-dependent deacetylase, SIR2 family OS=Mycoplasma iowae DK-CPA GN=P271_22 PE=4 SV=1
----------------------------------------KNIVFFGGAGVSTASGIPDFRSSNGLFDKISPEKIVSHDFLLHETEL---FYEFYFNNLV
YPNAKPNFTHKFIAWLEKYK-NV-IVVTQNIDDLHQHGGSSNVIQIHGTTSSYHCMNCFKKYS-LKDLKPSVPLCSCT--GIIRPDVTLYQEALDTVGKA
INAISNADVLIICGSSLVVYPASFYINY-FE-GEKLIIVNKQQTSYDK-YDIVINDDMNKVFKEIK-------------
>tr|S3JL55|S3JL55_TRESO NAD-dependent protein deacetylase OS=Treponema socranskii subsp. paredis ATCC 35535 GN=cobB PE=3 SV=1
--------------------------------------ESRSIVFFGGAGVSTESGIPDFRSTDGLYHQYPPEQMLSRSFFDANPAE---FYRFYREKLI
VKGVKPNAAHKKLAELEKAG-KLTAVVTQNIDGLHQAAGSKNVFELHGSTLRNYCMKCGTPYD-IDFAEGIPHC-TCG--GIVKPDVVLYEESLDCIEGA
VRAIRDADMLIIGGTSLVVYPAASLVNY-YR-GNKLVVINKTATGGDA-ITLVIRDSIGKVLGAVK-------------
>tr|S3KHS0|S3KHS0_TREMA NAD-dependent protein deacetylase OS=Treponema maltophilum ATCC 51939 GN=cobB PE=3 SV=1
--------------------------------------ESDNIVFFGGAGVSTESGIPDFRSTGGLYRQYPPETILSRSFFDSNPAE---FYRFYKKKLI
VKGVKPNAAHLKLAELEKAG-KLKAVITQNIDGLHQAAGSKTVYELHGSLLRNYCMNCRAFYT-ADEVQGVPRCSKCS--GILKPDVVLYEESLNILSKS
IDAIAKAETLIIGGTSLVVYPAASLIRY-FS-GRRLVLINKGETSADD-RDLIIRDSIGKVFEKIR-------------
>tr|H7ENK1|H7ENK1_9SPIO NAD-dependent protein deacetylase OS=Treponema saccharophilum DSM 2985 GN=cobB PE=3 SV=1
--------------------------------------KSSRIVFFGGAGVSTESGIPDFRSQDGLYSQMPPEYMVSRTCFDKQTKE---FFEFYREKLI
IKGVEPNVTHIRLAQLEKAG-KLLAVVTQNIDGLHQAAGSKNVYELHGSTLRNFCMNCGMPYG-IDFEKGIPRCEKCG--GIIKPDVVLYEEGLDVIDGA
LEAISSADTLIIGGTSLVVYPAAGFIRN-FR-GQNLVMINKSATNADS-NDLVIHDSLGKVFEKIR-------------
>tr|D6E7S8|D6E7S8_9ACTN NAD-dependent protein deacetylase OS=Gordonibacter pamelaeae 7-10-1-b GN=cobB PE=3 SV=1
--------------------------------------KPGRMVFFGGAGVSTESGIPDFRSPDGLYAQHPPEQMISRSFFDAHPAE---FFAFYSDRML
ALDAQPNRAHRKLAELEQAG-TLSAVVTQNIDGLHQKAGSERVLELHGSVLRNFCMDCGAAYP-VDELRGVPRCPACG--GIVKPDVVLYEEALDTLQAS
VDAIARADLLVVAGTSLAVYPAAGLIDF-FQ-GDHLVIVNRTPTPRDR-QDLCLAANVGDVFDF---------------
>tr|S6CLI2|S6CLI2_9ACTN Deacetylase OS=Adlercreutzia equolifaciens DSM 19450 GN=AEQU_2086 PE=4 SV=1
--------------------------------------APGLMVFFGGAGVSTESGIPDFRSADGLYAQYPPETMVSRSFFDAHPRE---FFDFYCDRML
ALDAAPNAAHRKLAELERQG-ALSAVVTQNIDGLHQKAGSQNVLELHGSVWRNFCMGCGASCT-AEELAGVPRCAHCG--AIVKPDVVLYEEPLDTVTAA
VRAIASADLLVIAGTSLAVYPAAGLIDY-FS-GDHLAIINRTPTPRDA-HDLCIPANVGDVLGY---------------
>tr|A0A099SFP3|A0A099SFP3_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. HMP27 GN=cobB PE=3 SV=1
--------------------------------------NSSNIVFFGGAGVSTESNIPDFRSSQGLYEIYSPEVMLSHSFFKKHTDE---FFQFYKEKMI
YRNAKPNKAHYSLAKLEELG-KLKAVITQNIDGLHQESGSKNVIELHGSVHRNYCTKCKKSFD-LDYMNVIPHCDECG--SIVKPDVVLYEEALNVINKA
IYHVRNAEVLIIGGTSLVVYPAASLVQY-FN-GKHLILINKTTTDYDN-RSLVIYDSIGKILGEVI-------------
>tr|R6DLU1|R6DLU1_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. CAG:230 GN=cobB PE=3 SV=1
--------------------------------------QSDNIVFFGGAGCSCESGIPDFRSSNGLYSRFTPEQLVSHTFFMRYPDE---FFSFYKKNLI
YPDAKPNGCHIALAQLEKLG-KLKAIATQNIDGLHQAAGSKTVYELHGSVLRNYCMDCHAYYD-EKFLADIPVCPVCG--GRVKPDVVLYEESLDTIENT
IQAISHADTLIIGGTSLVVYPAAGLIDY-FH-GKYLVLINKSTTSADQ-KDLVIHDSIGEVMKTAV-------------
>tr|A0A0L8EWU8|A0A0L8EWU8_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. DMHC 10 GN=cobB PE=3 SV=1
--------------------------------------DSNNIVFFGGAGCSCESGIPDFRSSNGLWNEFTPEQLVSHTFFMKYPEE---FFKFYKDKLI
YPEAKPNAAHITLAKLEKMG-KLKAIVTQNIDGLHQAAGSKIVYELHGSVLRNYCMKCGTFYD-EKFLEGIPTCPKCG--GTVKPDVVLYEEGLDIIRGA
VDAISKADTLIIGGTSLVVYPAAGLINY-FK-GKNLILINKSTTFADN-KDLVINDSIGKVFNEVM-------------
>tr|R6PQN6|R6PQN6_9FIRM NAD-dependent protein deacetylase OS=Firmicutes bacterium CAG:466 GN=cobB PE=3 SV=1
--------------------------------------ECDNIVFFGGAGVSTESGIPDFRGEKGIFTAYRPEIILSHSFFEAHPDI---FFQYYKKNLL
YPDAKPNDCHKALAKLEEMG-KLKSVVTQNIDDLHQKGGSKRVLELHGTLYRNYCLKCGKEFD-LDYTKGITRCDKCG--GIVRPDVVLYEEGLDTIEEA
VHDISHAQMLIVGGTSLNVYPAAGLLHY-FR-GKYLVLINKSATSMDK-KDLVIAENIGEVFRKVV-------------
>tr|A0A0L6JUA0|A0A0L6JUA0_9FIRM Silent information regulator protein Sir2 OS=Pseudobacteroides cellulosolvens ATCC 35603 = DSM 2933 GN=Bccel_4672 PE=4 SV=1
----------------------------------------SNIVAFTGAGVSTESGIPDFRSSAGIFQMFPPEVILSKTFFDKYPDK---FFEFYKKFMV
YSDVKPNQCHLALAKLEDAG-KLKAVVTQNIDNLHTIAGSKNVIELHGNANKNYCVKCNKKYD-AQYLNAVPKCDSCG--DIVRPDVVLYEEMLDKLYNA
KCHIRDADMVIVIGTSLVVYPAAKLIKY-FE-GDKLVIINMADTPFDA-SMILLRQKAGEVMKQVV-------------
>tr|R6VAW4|R6VAW4_9FIRM NAD-dependent protein deacetylase OS=Roseburia sp. CAG:380 GN=cobB PE=3 SV=1
--------------------------------------ESDNIVFFGGAGVSTASGIPDFRSSDGLYSQFTPEQLVSHSFFMRYPDD---FFDFYKKNLV
YPDAEPNDCHIALAKLEEMG-RLKAVITQNIDGLHQAAGSKTVYELHGSVLRNYCTKCHSFYD-ADFLAGIPLCPKCH--GVIKPDVVLYEEGLDVITGA
IQAISEADTLIIGGTSLVVYPAAGLIDY-FH-GRHLVLINKSSTPADS-KDLVINDSIDKVMREAL-------------
>tr|R7JWI2|R7JWI2_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. CAG:277 GN=cobB PE=3 SV=1
--------------------------------------ESDNIVFFGGAGVSTASNIPDFRSSNGLYSKFTPEQLVSHTFFVRYPEE---FFAFYKKNLV
YPDAKPNACHIALAKLEDMG-KLKAIVTQNIDGLHQAAGSKVVYELHGSVLRNYCTHCHEFYD-ADFLQGVPLCPKCH--ALIKPDVVLYEEGLDVITRS
IEAIQAADTLIIGGTSLVVYPAAGLINY-FH-GKHLVLINKSSTPADG-KDLVINDSIDKVMEKAV-------------
>tr|E2SMV9|E2SMV9_9FIRM NAD-dependent protein deacetylase OS=Erysipelotrichaceae bacterium 3_1_53 GN=cobB PE=3 SV=1
--------------------------------------QSDRIVFFGGAGVSTESNIPDFRSQSGIYSKYRAETMISSDFFHEHPEQ---FYDFYFHEMV
YEQAQPNDAHRALAKLEAMG-KLQAVITQNIDGLHQMAGSKKVLELHGSIHRNRCQRCHAFYD-LDE--QIPRCPVCN--GIIKPEVVLYGESLDVMEEA
VSYIAQADVLIVGGTSLVVYPAAGLIRY-FR-GRKLILINKEETAMDQ-RDQVIHDAIGKVMKHAV-------------
>tr|R6VPW9|R6VPW9_9FIRM NAD-dependent protein deacetylase OS=Erysipelotrichaceae bacterium CAG:64 GN=cobB PE=3 SV=1
--------------------------------------QSDNIVFFGGAGVSTESNIPDFRSQSGIYSKYRAETMISSEFFHEHPEQ---FYDFYFHEMV
YERAQPNDAHLALAKLEEMG-KLKAVITQNIDGLHQKAGSHKVLELHGSIHRNRCQRCRAEYD-LQE--QVPRCPSCN--GILKPEVVLYGESLDVMEEA
ILFLSQADVLIVGGTSLVVYPAAGLLQY-FR-GSKLILINKEETAMDH-RDLVIHDAIGKVMKEAV-------------
>tr|H1BJW1|H1BJW1_9FIRM NAD-dependent protein deacetylase OS=Eubacterium sp. 3_1_31 GN=cobB PE=3 SV=1
--------------------------------------ENKHIVFFGGAGVSTESNIPDFRSQSGIYSKYPAETMISHDFFYEHTEA---FYDFYFHEMV
YPNAQPNPAHLALAKLEALG-KLDAVITQNIDGLHQKAGSKKVLELHGSIHRNRCQSCHSFFT-LED--GIPKCPNCH--HTIKPEVVLYGESLDVMEEA
VTAIANADVMIIGGTSLVVYPAAGLLRY-FR-GKTLVLLNKAVTAMDD-QDIVIHDPIGEVLQEVV-------------
>tr|F5RJB7|F5RJB7_9FIRM NAD-dependent protein deacetylase OS=Centipeda periodontii DSM 2778 GN=cobB PE=3 SV=1
--------------------------------------GSSHAVFFGGAGMSTESGIPDFRSAGGIYSEFTPEQMASHSFLMAHPEE---FFDFYRRRFV
YLAAEPNPGHYALAELERRG-ILAAVVTQNIDGLHQAAGSQTVYELHGSIRRAHCMGCGAHYG-LDYLHPIPHCS-CG--GIVRPDVVLYEESLDTVEGA
VTAIRAADTLIIGGTSLIVYPAAGLIDY-FR-GEHLVLINKSETSADA-RELVIREPIGDVLHEAL-------------
>tr|E4LGL2|E4LGL2_9FIRM NAD-dependent protein deacetylase OS=Selenomonas sp. oral taxon 137 str. F0430 GN=npdA PE=3 SV=1
--------------------------------------ASRRAVFFGGAGMSTESGIPDFRSAGGIYSEYTPEQMASHSFLMAHPEE---FFDFYRSRFV
YLAAEPNPGHYAIAELERRG-ILAAVVTQNIDGLHEAAGSKTVYELHGSIRRAHCMDCGAHYE-LDFLHPVPYCTDCG--GIVRPDVVLYEESLDTIEGS
IAAIRAADTLIIGGTSLIVYPAAGLIDY-FH-GQHLVLINRTETRADG-RELVIREPIGDVLHEAL-------------
>tr|G4HDN7|G4HDN7_9BACL NAD-dependent protein deacetylase OS=Paenibacillus lactis 154 GN=cobB PE=3 SV=1
--------------------------------------ASDYIVFFGGAGTSTESGIPDFRSAAGLYQSYPPEVMLSHSFFMKHPEV---FYDFYRSKML
HPHAQPNGCHRLLSRLAREG-KLKAIITQNIDGLHQSAGCTDVLELHGSVHRNYCMECSRFFS-LQDLDTVPRCPDCG--GVIRPDVVLYEEELDILMRS
IQEISTADLLIIGGTSLTVHPAAGLVSY-FQ-GSKVALLNADPTPYDH-RGLLIADRIGEVMTEVD-------------
>tr|V9G543|V9G543_9BACL NAD-dependent protein deacetylase OS=Paenibacillus sp. JCM 10914 GN=cobB PE=3 SV=1
--------------------------------------ASDYIVFFGGAGTSTESGIPDFRSAAGLYQNYPPEVMLSYTFFKQHPEV---FYDFYRSKML
HPDAQPNGCHRLLAKLEADG-KLKATITQNIDGLHQSAGCTEVMELHGSVHRNYCMDCSRFYG-LHDQATVPRCLSCG--GLIKPDVVLYEEELDIILRS
IQEISTADLLIIGGTSLTVHPAAGLISY-FQ-GSKVALLNADPTPYDH-RGLLIADRIGEVMNQVD-------------
>tr|F3MB91|F3MB91_9BACL NAD-dependent protein deacetylase OS=Paenibacillus sp. HGF5 GN=npdA PE=3 SV=1
--------------------------------------ASDYIVFFGGAGTSTESGIPDFRSAAGLYQSYPPEVMLSHTFFMQHPEV---FYDFYRSKML
HPFAQPNGCHRLLSRLEHDG-KLKAVITQNIDGLHQSAGCSEVLELHGSVHRNYCMDCSRFYS-LQDLDIVPRCKDCG--GLVRPDVVLYEEELDVIMRS
IQEISTADLLIIGGTSLTVHPAASLISY-FH-GSKVALLNADPTPYDH-RGLLIADRIGQVMTQVD-------------
>tr|R6Z803|R6Z803_9ACTN NAD-dependent protein deacetylase OS=Collinsella sp. CAG:398 GN=cobB PE=3 SV=1
--------------------------------------THAHSVFFGGAGVSTASGIPDFRSADGLYSQYPPETMLSHSFYEAHPAD---FFAFYRERMI
ALDAQPNQCHRKLAELERSG-KLDAVVTQNIDGLHQAAGSRCVWELHGSVHRNICQRCGTVYS-ACQVSGIPRCPACG--GRIKPDVVLYEEPLNVIEGA
VRAIASADVLVVGGTSLVVYPAAGLLQY-FQ-GDTLVIVNRDPTPQDA-RDVLISCDIAQAFAF---------------
>tr|T4BUW4|T4BUW4_PEPDI Sir2 family protein OS=Peptoclostridium difficile F501 GN=QOE_3311 PE=4 SV=1
--------------------------------------PPGGLVFFGGAGVSTESGIPDFRSPDGLYAQYPPEQMVSRSFFDANPSA---FFDFYCDRML
ALDAQPNRTHRKLAELEQAG-TLAAVVTQNIDGLHQKAGSKNVLELHGSVLRNFCMACGAAYS-VDNLASVPRCPACG--GIVKPDVVLYEEPLNTVHGA
VNAIAQADLLVVAGTSLAVYPAAGLIDF-FT-GRRLVIVNRTPTPRDR-QDLCIAANVGEVFGF---------------
>tr|S2X1P8|S2X1P8_9ACTN Uncharacterized protein OS=Propionimicrobium lymphophilum ACS-093-V-SCH5 GN=HMPREF9306_00174 PE=4 SV=1
--------------------------------------KAKRGVFFGGAGVSTASGIPDFRSATGLYTTMPPEYMLSHSCYLQDPEA---FYDFHRAHMI
FPEAKPNGAHTALARLEELG-HIKAIVTQNCDGLHQEAGSKTVWELHGSVDRNYCPDG-HVYD-KVW--GVPHCPVDG--KQVRPDIVLYEEGLNVISEA
VRAIESADLLIIGGTSLNVYPAAGMINY-YR-GSHLVLINRDATPADN-QDLVIRDSIDDVMTAAV-------------
>tr|R5ZQC9|R5ZQC9_9ACTN Transcriptional regulator Sir2 family OS=Collinsella sp. CAG:166 GN=BN511_00275 PE=4 SV=1
--------------------------------------THKRVVFFGGAGVSTASGIPDFRSVDGLYHQYPPETMLSHSFYEAHPTE---FFDFYRTKMI
ALNAKPNRCHTKLAELERAG-KLDAVVTQNIDGLHQAAGSQRVFELHGSVHRNICQSCGAVYS-AEWCSGVPACPACG--GRIKPDVVLYEEPLDVLTGA
VAAIAAADALIVGGTSLVVYPAAGLTRY-FT-GDTLAICNLAPTDQDA-NDLLISCDIAAAFAF---------------
>tr|G1WK73|G1WK73_9ACTN Uncharacterized protein OS=Collinsella tanakaei YIT 12063 GN=HMPREF9452_01790 PE=4 SV=1
--------------------------------------THSRVVFFGGAGVSTASGIPDFRSQDGLYHQYPPETILSHSFYVANRGE---FYEFYRTKMI
ALDARPNQCHLKLAQLEREG-VLSAVVTQNIDGLHQMAGSKRVFELHGSVHRNVCQRCGATFD-AEWMAGAPVCPHCR--GEIKPDVVLYEEPLDVMIGA
IEAISQADALIVGGTSLVVYPAAGLTRY-FN-GDSLVIVNRDPTPQDS-RDLLISCDIAKAFDF---------------
>tr|R7D467|R7D467_9ACTN NAD-dependent protein deacetylase OS=Collinsella sp. CAG:289 GN=cobB PE=3 SV=1
--------------------------------------THGHAVFFGGAGVSTASGIPDFRSVDGLYHQYPPETMLSHSFFVSHKPD---FYNFYRKKMI
ALDAKPNRAHTKLAELEAAG-KLDAVVTQNIDGLHQMAGSKNVFELHGSVHRNVCQRCGKTYD-AAWMAGVPICPLCR--GEIKPDVVLYEEPLDVVNGA
VEAISHADMLIVGGTSLVVYPAAGLTRF-FN-GDKLVIINRDPTPQDH-NDLLISCDIAAAFDF---------------
>tr|E0E472|E0E472_9FIRM NAD-dependent protein deacetylase OS=Peptostreptococcus stomatis DSM 17678 GN=cobB PE=3 SV=1
--------------------------------------DSDNIVFFGGAGVSTESDIPDFRSSDGLFSKFSPEQLVSHTFYVHYPED---FYAFYKDKLI
YPDARPNKAHKALAYLEKIG-KLRAVVTQNIDGLHQMAGSKNVLELHGSVNSNTCQSCGYNMD-LKELDLVPKCPKCG--GSVKPDVVLYEESLNTIIKT
IKAISEADMLIVGGTSLVVYPAAGFLDY-FK-GRHIVLINKAETSYDR-RDLVINDSIGNVLDMAV-------------
>tr|R5JEK2|R5JEK2_9FIRM NAD-dependent protein deacetylase OS=Peptostreptococcus anaerobius CAG:621 GN=cobB PE=3 SV=1
--------------------------------------NAKRIVFFGGAGVSTESNIPDFRSSNGLFSKFSPEQLVSHTFFVRYTED---FFSFYKSNMI
YKDAKPNKAHLALAKLEKMG-KLDSIVTQNIDGLHQLAGNTRVFDLHGNINHNTCTSCKAKYN-LDELDPVPRCKKCG--SIVKPDVVLYEESLDTISGA
INSISKADLLIVGGTSLVVYPAAGFLDY-FK-GDHIVLINKSSTQLDS-RDLVINESIGKVLDDAI-------------
>tr|J6IES9|J6IES9_9FIRM NAD-dependent protein deacetylase OS=Selenomonas sp. CM52 GN=cobB PE=3 SV=1
--------------------------------------ESDNIVFFGGAGVSTESGIPDFRSATGIYSKVSPEELVSHTFFERCPEE---FFDFYRKRLV
YMEAKPNDCHKALAALERMG-KLKAVVTQNIDGLHQEAGSSRVLELHGSIRRSYCMDCRAFYD-ERFQAGVPHCTKCG--GIVKPDVVLYEESLDVLDAA
VRAIAAADLLIVGGTSLVVYPAAGLLRC-FK-GRHLVLVNKTATKADE-RDLVIHDSLGEVFREVM-------------
>tr|D4MVF2|D4MVF2_ANAHA NAD-dependent protein deacetylase OS=Anaerostipes hadrus GN=cobB PE=3 SV=1
--------------------------------------ESNHIVFFGGAGVSTESHIPDFRSTDGLYHQYPPEVMVSHTFYTQHTEE---FYDFYKNKMI
FLDAKPNKAHLKLAEMERAG-KLSAIVTQNIDGLHQAAGSKNVFELHGSVHRNYCQKCGKFFD-VNYVNGVPYCDECG--GIIKPDVVLYEEGLDTINGA
VRAISKADMLIIGGTSLVVYPAAGMIDY-FK-GKYLAVLNRDATSRDK-QDLCITDPIGEVLGRIR-------------
>tr|E5VR19|E5VR19_9FIRM NAD-dependent protein deacetylase OS=Anaerostipes sp. 3_2_56FAA GN=cobB PE=3 SV=1
--------------------------------------ESSRIVFFGGAGVSTESSIPDFRSTDGLYHQYPPEVIVSHTFFVQKTEE---FYDFYKKKMI
FPDAKPNPAHLKLAELEKTG-KLTAVVTQNIDGLHQKAGSQKVFELHGSVHRNYCQKCHKFFD-VNYAGGVPRCDECG--GLVKPDVVLYEEGLDVMRGA
VDAISEADMLIIGGTSLVVYPAAGMIDY-FH-GKHLVLINKDATSRDR-QELCITDPIGKVLGQIR-------------
>tr|E3GES2|E3GES2_EUBLK NAD-dependent protein deacetylase OS=Eubacterium limosum (strain KIST612) GN=cobB PE=3 SV=1
--------------------------------------EGKSIVFFGGAGVSTESGIPDFRSSNGLYMQYPPEQVVSHSFFVNHTEA---FYDFYKNKMM
FLDAKPNAAHMKLAELEKCG-KLKAVVTQNIDGLHQAAGSRTVYELHGSIHRNYCQKCGKFFD-AVYINGVPKCDACG--GMIKPDVVLYEEALDTIQKA
VQAISEADTLIIGGTSLVVYPAASFIDY-FR-GKNLVVINKDATARES-ESLAIHDAIGKVMEQIK-------------
>tr|L0EBD2|L0EBD2_THECK NAD-dependent protein deacetylase OS=Thermobacillus composti (strain DSM 18247 / JCM 13945 / KWC4) GN=cobB PE=3 SV=1
--------------------------------------ASDNIVFFGGAGVSTESNIPDFRSAGGLFSELSPEEILSHTFFMQHTEE---FYDFYKNKMI
YKDAKPNPAHLALARLEQAG-KLKAVITQNIDGLHQQAGSREVLELHGSVHRNYCMSCGQFFP-LDALEGVPKCSRCG--GIVKPDVVLYEESLDVLEKA
RRYIEQADVLIVAGTSLRVYPAAGLIRF-FR-GRHLVLINKSPTPYDH-ASLVIHDSIGKTLKACL-------------
>tr|R5FT78|R5FT78_9FIRM NAD-dependent protein deacetylase OS=Coprobacillus sp. CAG:698 GN=cobB PE=3 SV=1
--------------------------------------GSKHIVFFGGAGVSVESGIPDFRSANGLYSEIPVESILSHTFFINHPDK---FYDFYKNKMI
YLDAKPNPCHMALAYLEKIG-KLSCVITQNIDNLHTMAGSKNVYNLHGSIYSNHCMKCNKWFD-IDYINGVPKCDECG--GIVKPDVVLYEESLDVLTKS
IEEIEKADTLIIGGTSLTVYPAAGLVRY-FN-GKNLIIINKSVSNYDN-YSLVINENIGEVFEKVM-------------
>tr|R7BTM8|R7BTM8_9FIRM Transcriptional regulator Sir2 family OS=Firmicutes bacterium CAG:475 GN=BN674_00356 PE=4 SV=1
--------------------------------------NSHRIVVLTGAGASVPSGIPDFRSAHGLYATYPAETVISHDFFMVHPKE---FYDFYKSKMV
YPDAKPNAMHALLARLERSG-KIEGIVTQNIDGLHQAAGSKKVFELHGSIWRNRCERCRKFFD-LDY--GVPHCDECG--GIIKPEVVLYGENLDVLRGA
IRAIQRADMLIVVGTSLVVYPAAGLVGY-FC-GNVTAVINKSGTYFDS-QDVLLNADCREVATWLD-------------
>tr|I0XCE7|I0XCE7_9SPIO NAD-dependent protein deacetylase OS=Treponema sp. JC4 GN=cobB PE=3 SV=1
--------------------------------------KSKNIVFFGGAGVSTESGIPDFRSVDGLYNMYPPEQIISRTFFYENTKE---FYRFYREKLL
IKGVEPNAAHYKLAELEKAG-KLKAVVTQNIDGLHQKAGSKTVYELHGSVLRNYCEYCHAFYD-EKIEEKLPHCTKCG--GLIKPDVVLYEEGLDTINNS
IMAIKNADTLIIGGTSLTVYPAAGLVDY-FH-GENLVLINKTATMQDS-RSLVVRGKIGEVLGQIK-------------
>tr|A0A095XAD6|A0A095XAD6_9FIRM NAD-dependent protein deacetylase OS=Tissierellia bacterium S5-A11 GN=cobB PE=3 SV=1
----------------------------------------QRIVFFGGAGVSTESDIPDFRGTHGLFNRYSAEEMVSHHFYVEHPEE---FFSNYKVRQM
MKDVQPNRAHIMLAKLEKLG-KLQAIITQNIDGLHQRAGSQTVYELHGSIHRNYCTKCHASYS-IDDIEPIPHCDKCG--GIIKPDVVLFEEPLDTVFNA
IQAIRDADMLIIGGTSLVVWPAAGFIHE-FG-GDAVVLINQDSTPRDQ-ADILFRESIGQVLEDAI-------------
>tr|H1CZG9|H1CZG9_9FIRM Uncharacterized protein OS=Dialister succinatiphilus YIT 11850 GN=HMPREF9453_00762 PE=4 SV=1
--------------------------------------SHHKIAFFGGAGVSTESHIPDFRGANGIYRQWTPEEMLSHHFYEEHPVE---FFTNYKNFAE
AMAAEPNRAHYALARLEEEG-KLHGIVTQNIDGLHQKAGSQNVMELHGSILRNYCTQCGRSYD-VDSLSPVPHCPYCG--GIVKPDVVLYEEPLDTMEDA
MDAIQTADMLIIGGTSLVVYPAAGFIDY-FA-GDSLVMINQDETGRDS-TDLVFHDSVGKILGEVV-------------
>tr|R6AK07|R6AK07_9FIRM NAD-dependent protein deacetylase OS=Dialister sp. CAG:486 GN=cobB PE=3 SV=1
--------------------------------------SHHRIVFFGGAGVSTESNIPDFRGANGLYRQWTPEEMLSHHFYEEHPVE---FFTMYKQFAE
AMKASPNRAHFALAKLEQEG-RLSAVVTQNIDGLHQRAGSRNVIEVHGTILTNTCEKCFATYD-AKTLTPVPHCPSCG--GVIKPDVVLYEEALDDIDEA
IDEISKADMLIIGGTSLVVYPAAGFVTY-FR-GDALVVINQDAIAQDA-RDLVFHDSVGKVLERAV-------------
>tr|R7CM38|R7CM38_9FIRM NAD-dependent protein deacetylase OS=Dialister sp. CAG:357 GN=cobB PE=3 SV=1
--------------------------------------DHQHIVFFGGAGVSTESAIPDFRGKNGLYYQWSPEEMLSHHFYREHPDL---FFTMYKKMAE
TIHAKPNAAHRALAELEKMG-KLSGVVTQNIDGLHQKAGSRNVVELHGSTLHNTCEKCRKRYD-LPEISPVPHCD-CG--GIIKPDIVLYEESLDAIDDA
VWLIRGADMLIIGGTSLAVYPAAGFINE-FS-GDALVIINRDATSKDN-ADLVFRDNIGEVLGNTV-------------
>tr|J4NVP3|J4NVP3_9FIRM NAD-dependent protein deacetylase OS=Selenomonas sp. FOBRC6 GN=cobB PE=3 SV=1
--------------------------------------SSNRAVFFGGAGMSTESGIPDFRSAGGIYSEFAPEQMASHSFLMAHPAE---FFDFYRRRFV
YLSAAPNAGHYALAELERQG-HLAAVVTQNIDGLHQAAGSKTVYELHGSIRRAHCTDCGAHYE-LDYLHPVPHCS-CG--GIVRPDVVLYEESLDTIEGA
IAAIRAADTLIIGGTSLIVYPAAGLIDY-FR-GAHLVLINRSETRADR-RELVIREPIGDVLHEAL-------------
>tr|E0P104|E0P104_9FIRM NAD-dependent protein deacetylase OS=Selenomonas sp. oral taxon 149 str. 67H29BP GN=cobB PE=3 SV=1
--------------------------------------ASRRAVFFGGAGMSTESGIPDFRSAGGIYSEFSPEQMASHSFLMAHPVE---FFDFYRRRFV
YLDAAPNAGHTALAELERRG-HLAAIVTQNIDGLHQAAGSKTVYELHGSIRRAHCVDCGAHYE-LDYMEPIPCCS-CG--GTVCPDVVLYEESLDTIEGA
VAAIRAADTLIIGGTSLIVYPAAGLIDY-FR-GEHLVLINKSETRADR-RELVIRAPIGATLHAAL-------------
>tr|E6U979|E6U979_ETHHY NAD-dependent protein deacetylase OS=Ethanoligenens harbinense (strain DSM 18485 / JCM 12961 / CGMCC 1.5033 / YUAN-3) GN=cobB P
--------------------------------------TSERVVAFTGAGVSTESEIPDFRSSGGVYESQEPEVLLSHDFFMQNPAV---FYDYLRRYLV
FPDAEPNDAHKAFAMLERQG-KLSAVVTQNIDGLHSKAGSQTVYELHGSVYRNHCLSCGRRYG-LDV--SVPQC-ACG--GMIRPDVVLYGEGLDTVEGA
VRAIERADLLLVAGTSLAVYPAAGLIDY-FH-GEHLALLNKSGTPYDR-RDLCIRAAAGATLRAAM-------------
>tr|D4JPX2|D4JPX2_9FIRM NAD-dependent protein deacetylases, SIR2 family OS=Eubacterium rectale M104/1 GN=ERE_33950 PE=4 SV=1
----------------------------------------NNIVFFGGAGVSTESGIPDFRSKDGLYNNYKPEYLLSFACLYHEPEV---FFEFYKQKMD
TRKFKPNITHEVLAKLERMG-KLSAIVTQNIDGLHQKAGSKTVYEIHSTTAHCHCMNCGREYD-GSYFDSVPHCQYCEDKAIVRPDVVLYGENLPTVVKA
ISAIENADCLIVGGTSLTVWPASTFLNY-FK-GDHLIIVNNEPLDVPTNRDLIITDTLGNVFTKID-------------
>tr|U2D1H7|U2D1H7_CLOS4 Putative NAD-dependent deacetylase OS=Clostridium sp. (strain ATCC 29733 / VPI C48-50) GN=HMPREF0262_03489 PE=4 SV=1
--------------------------------------SCDNIVFFGGAGVSTESGIPDFRSEDGLYRQWPPETILSAGFFAAHPEE---FYRFYREKML
VTGAQPGPAHLALAELERRG-KLRAVITQNIDGLHQKAGSRRVYELHGTIYQNRCLSCGALCG-PEGGKGLPRCS-CG--GLIKPEVVLYGESLDTLQGA
VDAISRCEMLIVGGTSLAVYPAAGLLQY-YR-GHRLVLINKGPTPQDG-RDLLLRGSIGPILTEAI-------------
>tr|A0A095ZKM0|A0A095ZKM0_9FIRM NAD-dependent protein deacetylase OS=Clostridiales bacterium S5-A14a GN=cobB PE=3 SV=1
--------------------------------------KSSNIVFFGGAGVSTESGIPDFRSEKGLYHAYPPEMLISHTFYVKNPNL---FFKYYKENLV
WQDVQPNDAHKALAKLEQMG-KLKAVVTQNIDGLHQKAGNKTVYELHGSVLRNFCEHCGASYD-LDYMNYIPVCNKCG--GTIKPDVVLYEEALDVIYSA
VDAISKADTLIVGGTSLVVYPAAGLINY-FR-GKNLVLINKSQTAYDN-RTLAIHDSIGKVMKFD--------------
>tr|W2BZD5|W2BZD5_9FIRM NAD-dependent protein deacetylase OS=Eubacterium nodatum ATCC 33099 GN=cobB PE=3 SV=1
--------------------------------------ASNSIVFFGGAGVSTESGIPDFRSEKGLYHAYSPETMLSRGFYDKHCET---FYMYYKENLI
HEKAEPNDAHFALAKLEREG-KLKAVITQNIDGLHQKAGSKNVYELHGSVLRNFCQNCGKGYG-LEYMNGIPKCS-CG--GTIKPDVVLYGEALNVIGGA
VDAISKADLMIIGGTSLIVYPAAGLINY-FN-GKNLVLINKDETPYDS-RNLVIHDSIGKVMKL---------------
>tr|R5PJZ4|R5PJZ4_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. CAG:127 GN=cobB PE=3 SV=1
--------------------------------------QCNSIVFFGGAGVSTESGIPDFRSTDGLYNQYPPETIVSHSFYMQRTEE---FYEFYKDKML
FPQAQPNAAHKKLAELEQAG-KLKAVITQNIDGLHQAAGSKEVLELHGSVHRNYCTKCKKFFP-LSYVEGIPTCDECG--AIIKPDVVLYEEGLDILTRS
INHIAKADMLIIGGTSLAVYPAAGLIDY-FH-GKYLVVINMASTPRDS-YDIVINGKIGEVLSQIE-------------
>tr|R5E957|R5E957_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. CAG:590 GN=cobB PE=3 SV=1
--------------------------------------DSNNIVFFGGAGVSTESGIPDFRSVDGLYNQYPPEVMVSHSFFRQHTEE---FFEFYKNKMI
ALDAKPNAAHKKLAQLEQDG-KVKAVITQNIDGLHYAAGSKEVLELHGSVHRNYCEQCGKFYP-VEYV-GVPRCEACG--AIVKPDVVLYEEGLDTMQKA
VQYIRDAEVLIIGGTSLAVYPAAGFIDY-FR-GRHLVVINMDRTAKDV-HELLIQERIGEVFERL--------------
>tr|R6U394|R6U394_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. CAG:964 GN=cobB PE=3 SV=1
--------------------------------------QCNSIVFFGGAGVSTESGIPDFRSVDGLYNQYPPEEILSHTFFVKRTAE---FYDFYRDKML
CFTAKPNAAHLFLSELEKAG-KLSAVVTQNIDGLHQMAGSKKVYELHGSVHRNYCLSCGKFFS-GEYA-GIPHCDSCG--GIIKPDVVLYEEGLDTIEGS
VRAISNSDCMIVAGTSLTVYPAAGLIRY-FG-GKYLVLINKSQTSLDS-RDLVINQPVAQVLSKIK-------------
>tr|U2WFI1|U2WFI1_9FUSO Uncharacterized protein OS=Leptotrichia sp. oral taxon 225 str. F0581 GN=HMPREF9108_01150 PE=4 SV=1
--------------------------------------ESKRVVFFGGAGVSTESGIPDFRSANGVYNLFSPEELVSHTMYEKYPEE---FYDFYKKHLV
YPNAKPNFAHKYLARLEQDG-KLTAVITQNIDCLHEMAGSKNVLKLHGTVDSNTCVICGKKYN-MEELEKIPHCSKCG--GIIKPDVTLYEEVPDTFRKA
INEISKADTLIIGGTSLIVYPAASLIHY-FQ-GKNLVLINKSKTEQDN-FNLVIHESIGEVFKKLK-------------
>tr|A0A0K2JDF2|A0A0K2JDF2_9FUSO NAD-dependent protein deacetylase OS=Leptotrichia sp. oral taxon 212 GN=cobB PE=3 SV=1
--------------------------------------NSNKIVFFGGAGVSTESGIPDFRSADGLYSIFSPEQLVSHTMYLKYPEE---FYDFYKTNLI
YPDAEPNPAHYYLAELEKKG-KLTAVITQNIDSLHEMAGSRKVLKLHGSVDKNTCMSCGKKYN-LEELKPVPHCPKCD--GIIKPDVTLYEESLDIFEEA
IYHLSQADTLIIGGTSLVVYPAASLIQY-FR-GKNLVLVNKSVTSQDN-YNLVIHDSIGKVFGQLK-------------
>tr|D0GPL1|D0GPL1_9FUSO NAD-dependent protein deacetylase OS=Leptotrichia goodfellowii F0264 GN=cobB PE=3 SV=1
--------------------------------------ESKKTVFFGGAGVSTESGIPDFRSADGLYSIFSPEQLVSHTMYLKYPEE---FYQFYKTHLI
YPDAEPNFAHYYLAKLEQQE-KLSAVITQNIDCLHEKAGSRKVLKLHGSVDKNTCIDCGKKYN-LEELEGIPHCPECN--GIIKPDVTLYEETPDVFDEA
IRHLSRADTLIIGGTSLVVYPAASLIQY-FR-GNNLILINKSETSQDN-YDLVIHDRIGEVFKQLK-------------
>tr|U2RK01|U2RK01_9FUSO Putative NAD-dependent deacetylase OS=Leptotrichia wadei F0279 GN=HMPREF9015_00325 PE=4 SV=1
--------------------------------------ESKRIVFFGGAGVSTESGIPDFRSANGVYNLFSPEELVSHTMYEKYPEE---FYDFYKKHLV
YPEAKPNFTHKYLAKLEENG-KLTAIVTQNIDCLHEMAGSKNVLKLHGTIDKNTCVICGNKYN-LEELESIPHCPKCK--GTIKPDVTLYEEVPDTFRNA
INEISRADTLIIGGTSLVVYPAASLVQY-FQ-GKNLVLINKSKTEQDH-FNLVIHENIGEVFKKLK-------------
>tr|W1Q5Y3|W1Q5Y3_ABIDE NAD-dependent protein deacetylase OS=Abiotrophia defectiva ATCC 49176 GN=cobB PE=3 SV=1
--------------------------------------DSHHLVFFGGAGVSTESGIPDFRSAQGVYSQFSAEQLISHSMYQKYPQL---FYDFYRKHLI
YPHAKPNAAHIFLAQLEASG-HLDAVISQNIDTLHEAAGSQCVLKLHGTVDRNICQECGRVYD-LKSLDGIPRCPHCG--GVLKPDVTLYEESLNVFDQA
ILAIQQADTLIVGGTSLVVYPAAGLLQY-FK-GKHLVVINKQAIPQDD-WDLVIHAPIGQVFSQLV-------------
>tr|R9MXE8|R9MXE8_9FIRM NAD-dependent protein deacetylase OS=Lachnospiraceae bacterium 10-1 GN=cobB PE=3 SV=1
--------------------------------------SSKNIVFFGGAGVSTESGIPDFRSVDGLYNQYPPETILSHTFYRNKPEE---FFRFYKDKML
CLDAKPNAAHLKLARWEQEG-KLKAVITQNIDGLHQAAGSRKVLELHGSVLRNYCERCGKFFD-AEYL-GVPKCDACG--GAVKPDVVLYEEGLDTLKDA
VSYIRNADVLIIGGTSLVVYPAAGLIDY-YD-GNKLVLINKTPTARDD-ADLVVQGSIGEIFGAL--------------
>tr|R5V4W7|R5V4W7_9FIRM NAD-dependent protein deacetylase OS=Roseburia sp. CAG:18 GN=cobB PE=3 SV=1
--------------------------------------ESGNIVFFGGAGVSTESGIPDFRSVDGLYNQYPPETILSHSFYRQNPEE---FYRFYRNKML
CLDAQPNITHFKLAELEKAG-KLKGVVTQNIDGLHQKAGSKNVMELHGSVLRNYCERCGQFVS-AEDL-GVPVCPVCG--GPVKPDVVLYEEGLNTLQDA
VFYISHADMLIVGGTSLAVYPAAGLIDY-YR-GNKLVLINKSATPMDA-RDLLIQDGLGNVFSQIK-------------
>tr|R6N114|R6N114_9FIRM NAD-dependent protein deacetylase OS=Eubacterium sp. CAG:202 GN=cobB PE=3 SV=1
--------------------------------------DSRRIVFFGGAGVSTESGIPDFRSVDGLYNQYPPETILSHTFFVKKTEE---FYRFYRDKML
CLDKKPNKAHYKLAELEKVG-KLSAVVTQNIDGLHQAAGSKRVYELHGSVLRNYCMKCGKAYT-AEFK-GIPKCE-CS--GIIKPDVVLYEEGLDTVNGA
VNAIANADMLIIAGTSLTVYPAAGMVRY-FK-GNKLVLINRDATPMDS-ADLVFHEKVGELLDKIK-------------
>tr|D6E2V0|D6E2V0_9FIRM NAD-dependent protein deacetylase OS=Eubacterium rectale DSM 17629 GN=cobB PE=3 SV=1
--------------------------------------ASDNIVFFGGAGVSTESGIPDFRSVDGLYNQYPPETILSHTFYRKHPQE---FYRFYRDKML
CLDAEPNITHYKLAELEKAG-KLKGVVTQNIDGLHQKAGSKNVMELHGSVLRNYCERCLQFVS-AEEL-DVPKCPKCG--GPVKPDVVLYEEGLNTLEDA
IYYISHADVLIVGGTSLAVYPAAGLIDY-YN-GNKLVLINKSTTPMDA-RDLLIQQGLGSVFEQIE-------------
>tr|A6P1S7|A6P1S7_9FIRM NAD-dependent protein deacetylase OS=Pseudoflavonifractor capillosus ATCC 29799 GN=cobB PE=3 SV=1
--------------------------------------ESSRIVFFGGAGVSTESGIPDFRSVDGLYNQYPPETILSHTFYEARPEE---FFRFYRNKML
FPDAQPNAAHKKLAELEQAG-KLTAMVTQNIDGLHQKAGSKNVLELHGSVLRNYCEKCGKFFS-LEDM-GVPRCDKCG--GRVKPDVVLYEEALDILTAA
LEAIQKADMLIIGGTSLAVYPAASLVNY-YR-GNKLVLINKSPTPYDR-NDLVIAAPIGQVLGGIT-------------
>tr|G4KSP4|G4KSP4_OSCVS NAD-dependent protein deacetylase OS=Oscillibacter valericigenes (strain DSM 18026 / NBRC 101213 / Sjm18-20) GN=cobB PE=3 SV=1
--------------------------------------GSDNIVFFGGAGVSTESGIPDFRSTDGLYHQYPPETILSHTFYESKPEE---FFRFYRAKLL
APSAKPNPAHVKLAELERQR-KLKAVITQNIDGLHQAAGSREVLELHGSVHRNYCEKCGKFHD-FDFL-GVPRCTACG--GRVKPDVVLYEEGLDTMERA
VRFISEADMLIIGGTSLNVYPAAGLIRY-YR-GRKLVLINKSAVAADL-NDLVITEPIGETLVQI--------------
>tr|R6RSJ5|R6RSJ5_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. CAG:58 GN=cobB PE=3 SV=1
--------------------------------------ESENIVFFGGAGVSTESKIPDFRSTDGLYNQYPPETILSHTFYMRRTEE---FYRFYRNKML
FPDAEPNRAHKALAKLEQEG-RLRAVITQNIDGLHQKAGSREVLELHGSVLRNYCTKCGKFYG-LEALEGVPRCT-CG--GVIKPDVVLYEEGLDTLQKA
VYYISNADVLIIGGTSLTVYPAAGLIDY-YG-GKKLVLINKSVTPMDS-RDLVISGPIGEILGDAA-------------
>tr|D7GS83|D7GS83_9FIRM NAD-dependent protein deacetylase OS=butyrate-producing bacterium SS3/4 GN=cobB PE=3 SV=1
--------------------------------------ESSNIVFFGGAGVSTESHIPDFRSTDGLYNQYPPETILSHSFYMRKPEE---FYRFYRNKML
FPNAEPNRAHKALAKLEKMG-KLKAVVTQNIDGLHQKAGSREVLELHGSVLRNYCTRCGKFYG-LDALNGVPKCT-CG--GTIKPDVVLYEEGLDTIEKS
VKYIANADVLIIGGTSLTVYPAAGLIDY-YR-GHKLVLINKSVTPMDN-RDLVISGPIGEVLGDAV-------------
>tr|R6EGP0|R6EGP0_9FIRM NAD-dependent protein deacetylase OS=Firmicutes bacterium CAG:65 GN=cobB PE=3 SV=1
--------------------------------------TYDNIVFFGGAGVSTESGIPDFRSVDGLYHQYPPETILSHSFYRSHPEE---FFRFYRNKML
FPKAQPNAAHKKLAELERAG-KVRAVITQNIDGLHQAAGSKTVLELHGSVLRNYCEKCHQFYG-LNAL-GIPHCEKCG--GTIKPDVVLYEEGLDTINAA
VRYIHEADVLIIGGTSLAVYPAAGLIDY-FQ-GDKLVVINKSATPRDK-NDLLIQGPIGEVFHSIQ-------------
>tr|U1WTW2|U1WTW2_9ACTN NAD-dependent protein deacetylase OS=Atopobium sp. oral taxon 810 str. F0209 GN=cobB PE=3 SV=1
--------------------------------------KARNVVFFGGAGVSTASGIPDFRSPNGLYRQYSPEEMLEHRFFMEHTQE---FYDFYRTCMI
ALGARPNQAHLKLAELEREG-KLAAVVTQNIDGLHQAAGSHQVYELHGSVHRNICQHCGKTYS-AEWVAGVPHCEYCG--GLIKPDVVLYGESLNVLYGA
AQAIAEADMLIVGGTSLVVYPAAGLVQY-FQ-GNDLAIVNMQSTPQDA-MDLVCVCDIAKAFDF---------------
>tr|E1QXW5|E1QXW5_OLSUV Silent information regulator protein Sir2 OS=Olsenella uli (strain ATCC 49627 / DSM 7084 / CIP 109912 / JCM 12494 / VPI D76D-27
--------------------------------------RASHTVFFGGAGVSTASGIPDFRSENGLYRQYPPEELLSHHLWRERPEL---FYDFYRTMMC
TPDARPNQAHLKLAQLEAED-GLDVVITQNIDGLHQKAGSKNVVELHGSTKRNHCMGCGALYD-EAWLAGVPHCKRCG--GVVKPDVVLYEEPLGDVRAA
VEAISASDLLIIGGTSLVVYPAAGLVRY-FR-GDAIIIVNLQPTPQDA-GDVVCACDIASAFDW---------------
>tr|A0A0K1F1K9|A0A0K1F1K9_9ACTN NAD-dependent deacetylase OS=Olsenella sp. oral taxon 807 GN=ADJ70_03720 PE=4 SV=1
--------------------------------------RAKDVVFFGGAGVSTASGIPDFRSPSGLYNQYSPEELLSHHFYLQHPEE---FFDFYRKMMC
APEARPNQAHKKLAQLEAEG-KLSAVITQNIDGLHQAAGSKHVIELHGSTHRNVCQSCGTVYS-QEWLSGVPVCESCG--GRVKPDVVLYEEALDDIVAA
VDAISHCDMLIIGGTSLVVYPAAGLVQY-FS-GDDLVICNMGGTPQDG-RDLVCDCDIAGAFDW---------------
>tr|U2V9Q1|U2V9Q1_9ACTN NAD-dependent protein deacetylase OS=Olsenella profusa F0195 GN=cobB PE=3 SV=1
--------------------------------------KAHDMVFFGGAGVSTASGIPDFRSPGGLYHQYSPEELLSHHLYVEHPEE---FFDFYRTMMC
APDARPNQVHRKLADLEREG-RLRAIITQNIDGLHQAAGSRNVIELHGSTHRNVCQRCGRMYS-QEWLAGVPHCEACG--GPIKPDVVLYEEALDNLVAA
VTALSEADLLVIGGTSLVVYPAAGLVSY-FS-GNDLVICNQEPTPEDA-RDLVCACDIARAFDW---------------
>tr|U5N042|U5N042_CLOSA NAD-dependent protein deacetylase OS=Clostridium saccharobutylicum DSM 13864 GN=cobB2 PE=3 SV=1
--------------------------------------ESNNIVFFGGAGVSTASKIPDFRSSNGLFSQFTPEQLVSHTFYMRYPEE---FFQFYKDKLI
YPNAKPNNAHIALAKLEQLG-KLKAIVTQNIDGLHQMAGSKNVFELHGSVHRNHCTKCHAFYD-AEFLKGVPICSKCG--GRVKPDVVLYEEGLDVINGA
IGAISKADTLIIGGTSLVVYPAAGLINY-FN-GKNLVLINKSTTSADN-KNLVINDNIDKVLFKAI-------------
>tr|A0A0K2M7D6|A0A0K2M7D6_CLOPA NAD-dependent protein deacetylase OS=Clostridium pasteurianum NRRL B-598 GN=cobB PE=3 SV=1
--------------------------------------NSNNIVFFGGAGISTESNIPDFRGSNGLFSELTPEQLVSHTFYIKYPEE---FFKFYKAKLI
YPDAKPNAGHLALAKLEEMG-KLKAIVTQNIDGLHQMAGSKNVFELHGSIHRNYCVKCHESYD-VNFLQGVPICTKCG--GAVKPDVVLYEEGLDVIRDS
INAISNADTLIIGGTSLVVYPAAGLINY-FK-GKNLVLINKSSTSADS-KNLVINDSFGKTLSDAI-------------
>tr|D9SRK0|D9SRK0_CLOC7 NAD-dependent protein deacetylase OS=Clostridium cellulovorans (strain ATCC 35296 / DSM 3052 / OCM 3 / 743B) GN=cobB PE=3 SV=1
--------------------------------------NSDNIVFFGGAGVSTESNIPDFRSSNGLFNEFTPEQLVSHTFYIKYPEE---FFKFYKDKLI
YPKAKPNAAHLALAKLEDLG-KLKAIVTQNIDGLHQAAGSKNVFELHGSVHRNYCLKCHSSYD-AKFLEGIPTCTKCG--GNVKPDVVLYEEGLDIVTGA
VEAISKADVLIIGGTSLVVYPAASLIRY-YN-GNKLVLINKSETPYDN-NDLVINDSIGKVLSSVM-------------
>tr|U2NJF4|U2NJF4_9CLOT NAD-dependent protein deacetylase OS=Clostridium intestinale URNW GN=cobB PE=3 SV=1
--------------------------------------NSNNIVFFGGAGVSTESGIPDFRSASGLFNEFTPEQLVSHTYFMRYTED---FYKFYKDKLI
YEEAKPNDAHLALAKLEKLG-KLKAVITQNIDGLHQAAGSKNVFELHGSVHRNYCTKCHKFYP-VEFLKKTPTCTDCG--GTVKPDVVLYEEGLDVINGA
VNAIAHADTLIIGGTSLVVYPAAGLINY-FK-GKNLILINKSTTSADT-KDLVIHDSIGKVLKECT-------------
>tr|A0A0B2JZ17|A0A0B2JZ17_9FIRM NAD-dependent protein deacetylase OS=Anaerovibrio lipolyticus GN=cobB PE=3 SV=1
--------------------------------------KSRSMVFLGGAGISTESGIPDFRSAKGLYNRFTPEEMVSHTFLEDHPKE---FFDYYKKNLI
YLDAKPNNAHKALAKLEEMG-KLKAVVTQNIDGLHQMAGSKRVIELHGSVHRNFCVKCHATYD-AEFVNGIPTCSKCG--GMVRPDVVLYEEALNDIIDA
EEAITKADTMIVGGTSLMVYPAASLVRY-FR-GMNLIVINKTATPADE-WDLVIHDAAGKVLKACV-------------
>tr|M1M157|M1M157_9CLOT NAD-dependent protein deacetylase OS=Clostridium saccharoperbutylacetonicum N1-4(HMT) GN=cobB2 PE=3 SV=1
--------------------------------------ASNNIVFFGGAGVSTESNIPDFRSSTGLFNEFTPEQLVSHSFYIRYPEE---FFNFYKSKLI
YPEAKPNSGHLALAKLEDIG-KLKAIVTQNIDGLHQMAGNKHVFELHGSVHRNYCTKCHEFYD-AKFLEGAPICTKCG--GSVKPDVVLYEEGLDVIRGA
VDAISKADTLIIGGTSLVVYPAAGLINY-FK-GKNLVLINKSSTSADS-KDLVINDSIGAVLSAAV-------------
>tr|C0FZZ3|C0FZZ3_9FIRM NAD-dependent protein deacetylase OS=Roseburia inulinivorans DSM 16841 GN=cobB PE=3 SV=1
--------------------------------------ESDNIVFFGGAGVSTESGIPDFRSVDGLYNQYPPETILSHSFYVNHTEE---FYRFYRDKML
CLTAKPNTTHYKLAELEKAG-KLKAVVTQNIDGLHQAAGSKNVLELHGSVHRNYCRKCGKEFD-AEYLNGVPVCDSCG--GQIKPDVVLYEEGLNTLEDA
VYYISHADMLIIGGTSLAVYPAAGLIDY-YR-GNKLVLINKSTTSMDS-RDLLIQAGLGEVFGQVR-------------
>tr|R5TE46|R5TE46_9FIRM NAD-dependent protein deacetylase OS=Roseburia sp. CAG:50 GN=cobB PE=3 SV=1
--------------------------------------DSDNIVFFGGAGVSTESGIPDFRSVDGLYHQYPPETILSHTFYMEKTEE---FYRFYRDKML
ALDAKPNAAHLKLAELEAKG-KLKAVVTQNIDGLHQAAGSKNVLELHGSVHRNYCRKCGKLYD-AQYK-GVPMC-SCG--GQIKPDVVLYEEGLDTMQAA
IRAISQAEVLIIGGTSLAVYPAAGLIDY-YR-GNKLVLINKSATPLDS-RNLVIQAPIGEVFSAVC-------------
>tr|R6NKP9|R6NKP9_9FIRM NAD-dependent protein deacetylase OS=Roseburia sp. CAG:45 GN=cobB PE=3 SV=1
--------------------------------------DSDNIVFFGGAGVSTESGIPDFRSVDGLYNQYPPETILSHSFYMRKKEE---FYRFYRDKML
CLDAKPNAAHKKLAELEAAG-KLKAVVTQNIDGLHQAAGSKKVLELHGSVHRNYCQSCGKLFD-AEYL-GIPTCDECG--GSIKPDVVLYEEGLDTLEDA
VYYISHADMLIIGGTSLAVYPAAGLIDY-YR-GNKLVLINKSTTPLDN-RDLLIQGSIGAVLSEV--------------
>tr|R7R0K3|R7R0K3_9FIRM NAD-dependent protein deacetylase OS=Roseburia sp. CAG:182 GN=cobB PE=3 SV=1
--------------------------------------DSDNIVFFGGAGVSTESGIPDFRSVDGLYHQYPPETILSHSFYMSKTEE---FYRFYRDKML
CLTAKPNAAHKKLAELEQAG-KLKAIVTQNIDGLHQAAGSKVVLELHGSVHRNYCRHCGKLFD-ARYL-GIPTCDACG--GQIKPDVVLYEEGLDTLEDA
VRYISEADVLIIGGTSLAVYPAAGLIDY-YR-GNKLVLVNKSATPMDV-RDLLVQGSIGEIFSKIE-------------
>tr|D4KTL5|D4KTL5_9FIRM NAD-dependent protein deacetylase OS=Roseburia intestinalis M50/1 GN=cobB PE=3 SV=1
--------------------------------------ESDNIVFFGGAGVSTESGIPDFRSVDGLYNQYPPETILSHTFYMRHTEE---FYRFYRDKML
CLDAKPNVTHQKLAELEAAG-KVKAVITQNIDGLHQMAGSRHVLELHGSVHRNYCQKCGKGFD-AEYL-EIPLCDACG--GKIKPDVVLYEEGLNTLEDA
VFYISHADVLIIGGTSLAVYPAAGLIDY-YR-GNKLVLINKSTTPMDG-RDLLIQAGLGEVFSQIR-------------
>tr|G2T4Z6|G2T4Z6_ROSHA NAD-dependent protein deacetylase OS=Roseburia hominis (strain DSM 16839 / NCIMB 14029 / A2-183) GN=cobB PE=3 SV=1
--------------------------------------ESDNIVFFGGAGVSTESGIPDFRSVDGLYNQYPPETILSHSFYIKYPEE---FYRFYRDKML
CLDAEPNITHKKLAELEAAG-KVKAVVTQNIDGLHQLAGSKRVLELHGSVHRNYCRKCGKGFD-AEYR-KVPLCDACG--GTIKPDVVLYEEGLDTLEDA
VFYISHADMLIIGGTSLAVYPAAGLIDY-YR-GNKLVLINKSTTPMDA-RDLLIQAGLGDVFGQIE-------------
>tr|D3LV15|D3LV15_9FIRM NAD-dependent protein deacetylase OS=Megasphaera genomosp. type_1 str. 28L GN=cobB PE=3 SV=1
--------------------------------------SSQNIVFFGGAGVSTESGIPDFRSTDGLYNQYPPETILSHSFYRSQPHE---FYRFYHDKML
CLTAQPNAAHYALAALEKEG-KLKAVITQNIDGLHQKAGSRNVLELHGSIHRNFCESCGKFFA-ASYA-DIPRCDVCG--GTIKPDVVLYEEGLDVLQAA
LQYIRQADMLIIGGTSLVVYPAAGLVRY-YR-GHKLVLINKSTTDMDT-ADLILRYPIGETFEKAG-------------
>tr|N2B5K5|N2B5K5_9FIRM NAD-dependent protein deacetylase OS=Eubacterium plexicaudatum ASF492 GN=cobB PE=3 SV=1
--------------------------------------NTNNIVFFGGAGVSTESGIPDFRSVDGLYNQYPPETILSHSFYISKPEE---FYRFYFDKIL
CLDAKPNAAHVKLAELEQSG-KLKAVITQNIDGLHQMAGSKEVLELHGSIHRNYCRKCAKRFD-AIYK-GVPLCDECG--GSIKPDVVLYEEGLDTMEKA
VMYISKADILIIGGTSLAVYPAAGLIDY-YR-GNKLVLINKSATPMDK-CDLLIQGSIGEIFSQIR-------------
>tr|B9Y8H0|B9Y8H0_9FIRM NAD-dependent protein deacetylase OS=Holdemania filiformis DSM 12042 GN=cobB PE=3 SV=1
--------------------------------------RGKRIVFFTGAGASTESGIPDFRSVDGLYQQYPPEEIISHHFFESNPKE---FYRFYRSRML
YPNARPNAAHRLMAELEKTG-RCLGVVTQNIDNLHTLAGSQHVAELHGSIMRNYCVNCHHEEG-LDFLKDLPRCPVCG--GLMKPDVVLYEEALDVMDRA
LTWIQQSDVLIICGTSLSVYPAASMVRY-FY-GDQLVVINKTATSMDK-NDLHLLAPLAETLAQLH-------------
>tr|A0A096B521|A0A096B521_9FIRM NAD-dependent protein deacetylase OS=Clostridium orbiscindens 1_3_50AFAA GN=cobB PE=3 SV=1
--------------------------------------ESRHIVFFGGAGVSTESGIPDFRSVDGLYHQFPPETILSHSFFERNPEE---FYRFYRSKML
FPQARPNAAHWKLAELEAAE-KLTAVVTQNIDGLHQAAGSKTVYELHGSVHRNHCMKCRRFYG-LDFL-GVPRCPACG--GVVKPDVVLYEECLDTMVGA
VEAIAGADMLIIGGTSLAVYPAAGLIRY-YR-GNRLALINKSATPYDR-EGLVINASLGEVLGAIR-------------
>tr|R6VTP1|R6VTP1_9FIRM NAD-dependent protein deacetylase OS=Ruminococcus sp. CAG:382 GN=cobB PE=3 SV=1
--------------------------------------SSENIVFFGGAGVSTESGIPDFRSADGIYSRIPPERILSHTFFINHTAE---FFDFYKSNMI
FPDAKPNAAHLALASLESDG-KLRAVVTQNIDGLHQAAGSKKVFELHGSVHRNHCMECGRFFD-AAYM-GIPKCDVCG--GVVKPDVVLYEEALDVCDGA
VRAIADADMLIVGGTSLSVYPAAGFVRY-YS-GSRLVIINASATRYDD-LDFTISMPIGKVLGKAV-------------
>tr|R7I9U3|R7I9U3_9FIRM NAD-dependent protein deacetylase OS=Faecalibacterium sp. CAG:74 GN=cobB PE=3 SV=1
--------------------------------------ESRRIVFFGGAGVSTESGIPDFRSQDGLYHQYPPEEILSHTFFARHPEE---FYRFYRAKML
PLDAQPNDAHRFLAQLEAGG-RLTAVITQNIDGLHQKAGSKTVLELHGSIHRNYCLKCARFFP-PEYR-GVPKCP-CG--GIIKPDVVLYEEGLDTVRAA
VRQLQQAELLIVAGTSLTVYPAASLLRF-FR-GRHIVLINRDATPLDN-QDLVLHERVGEVCRHLR-------------
>tr|F9MQ19|F9MQ19_9FIRM NAD-dependent protein deacetylase OS=Megasphaera sp. UPII 135-E GN=cobB PE=3 SV=1
--------------------------------------DASRIVFFGGAGVSTESGIPDFRSTDGLYH-FPPETILSHSFYLSHTEE---FYRFYRDKML
CLSASPNTAHQVLATLEKMG-KLTAIITQNIDGLHQKAGSQHVLELHGSVLRNFCQSCHAFFS-ADD--IIPHCPHCG--GTIKPDVVLYEESLDVLQES
VNQLQKADLLLVGGTSLVVYPAAGLLHY-YR-GKHIVLLNKAATDMDK-KDLIFRQPIGQVLGQLH-------------
>tr|U2USU0|U2USU0_9FIRM NAD-dependent protein deacetylase OS=Oribacterium sp. oral taxon 078 str. F0263 GN=cobB PE=3 SV=1
--------------------------------------EARNIVFFGGAGVSTESGIPDFRSQDGLYRQYPPEQIISHSFFEANPEE---FYRFYREKML
FPEAKPNRAHLALARLEEEG-KLRAVITQNIDGLHQKAGSKKVYELHGSVWRNHCLRCGKSYP-LDFL-GVPRCS-CG--GIVKPDVVLYEEGLDVLQGA
AEAIREADLLIVGGTSLVVYPAAGLLRY-FD-DSALVLINKSETACDG-RDLVIRESIGDVLGSVV-------------
>tr|R5HC27|R5HC27_9FIRM NAD-dependent protein deacetylase OS=Firmicutes bacterium CAG:114 GN=cobB PE=3 SV=1
--------------------------------------ESDNIVFFGGAGVSTESGIPDFRSVDGLYHQYPPETILSHSFFAQNPGE---FYRFYREKML
IQGAQPNAAHRKLAELEQAG-KLKAVVTQNIDGLHQAAGSKVVYELHGSTLRNYCTRCKKKYP-VSFL-GIPRCTECG--AIVRPDVVLYEEGLDVISGA
VNAIRKADMLIIGGTSLVVYPAAGLINY-YT-GNKLVLINKGQTSADA-MNLTINAPIGEVFSQIT-------------
>tr|C2L144|C2L144_9FIRM Transcriptional regulator, Sir2 family OS=Oribacterium sinus F0268 GN=HMPREF6123_2463 PE=4 SV=1
--------------------------------------KANYIVFFGGAGVSTESGLPDFRSVDGLYHQFPPEEILSHDFFMARPKE---FYQFYKEKLL
IPGILPNPAHYALQRLEEQG-KLKAIITQNIDGLHQMAGSKAVYELHGSIHRYYCVKHHHQIP-EEEDFSIPLCPHCH--SIIRPDVVLYQEGLDILSES
IAHIQNADLLIIGGTSLTVYPAAGLIRY-FPHSNKLVLINKEEGRLDT-EDLVLYGKIGEILSEVV-------------
>tr|R6ALU9|R6ALU9_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. CAG:138 GN=cobB PE=3 SV=1
--------------------------------------SSRRVVFLGGAGVSTESGISDFRSENGIFKAYPPEELLSHTFFVRKPDV---FFRYYKTLLL
TTDAKPNAAHAALAKLEAQG-KLTAVVTQNIDGLHQLAGSKNVYELHGSIHRNHCMRCNRFFD-AEYKNGIPYCP-CG--GMIKPDVVLYEESLDVLAGA
VAHISRADMLIVGGTSLQVYPAAGLINY-YS-GNKLVLINKTITPYDN-YNLVINDSIGKVLSAAV-------------
>tr|C9LR22|C9LR22_9FIRM NAD-dependent protein deacetylase OS=Dialister invisus DSM 15470 GN=cobB PE=3 SV=1
--------------------------------------SHNRIVFFGGAGVSTESDIPDFRGKGGLYRQWSPEEMLSHHFYAEHPVE---FFTLYKEREG
MMEAEPNRAHTALAELEKMG-KLSAVVTQNIDGLHQKAGSRKVIELHGSVLRNICQKCGRMYG-MEEMEPVPHCPGCG--GVVKPDVVLYEEMLDTIEDA
IDEISRADMLIIGGTSLVVYPAAGYVDY-FQ-GDSLVMINRDETPRDS-RSLVFRESVGKVLEAGV-------------
>tr|I5AVT6|I5AVT6_EUBCE NAD-dependent protein deacetylase OS=[Eubacterium] cellulosolvens 6 GN=cobB PE=3 SV=1
--------------------------------------ASEHIVFFGGAGVSTESGIPDFRSKDGLYNQYSPEYLLSDDCLYRQPKV---FYEFYRQKLN
VDGIEPNAAHRKLAELEQRG-KLDCVITQNIDGLHQKAGSRRVFEIHGSTLRNYCSDCGKPYP-EDY--PIPRCPECG--GQIRPDVTLYGEALPAWTSA
ERAVSGADMLIIGGTSLSVYPAASLIDY-FR-GNYLVVINRDATNRDK-SDLVFHESIGQVLSHIQ-------------
>tr|A0A0R2HAV8|A0A0R2HAV8_9FIRM NAD-dependent deacetylase OS=Kandleria vitulina DSM 20405 GN=IV49_GL000933 PE=4 SV=1
----------------------------------------SHIVFFGGAGVSTESGIPDFRSADGLYNTYAPEYLLSHDCLFNESKV---FFEYYRQKLD
TRNIKPNKAHSVLALMEKKG-KLDGIITQNIDGLHQKAGSHKVWEIHGSTLNNYCSRCGKTYP-SDYFNGLPIC-GCG--GLIRPDVTMYGEALPAWTQA
IRLIKQADCLIVGGTSLSVYPAANLVTY-FK-GKHLVMINRDQTPYDY-KDLVIHDSIGKVFGEIE-------------
>tr|M2P991|M2P991_9FIRM Uncharacterized protein OS=Eggerthia catenaformis OT 569 = DSM 20559 GN=HMPREF9943_00695 PE=4 SV=1
----------------------------------------RHIVFFGGAGVSTESGIPDFRSKEGLYNNYSPEYLLSHECLYYNSKV---FYEFYRQKMN
ILDITPNDTHNKLALMEEKG-KLDCIITQNIDGLHQKAGSKRVYEIHGTVLHNYCDCCFKRYP-SDYFKSIPLC-KCG--GMIRPDVVLYGETLPAYRQA
INAIEHADCLIIGGTSLNVYPATGMIDY-FN-GKYLILINKDRTVRDS-DSLVFHESIGYVMNQII-------------
>tr|F7V2Y8|F7V2Y8_CLOSS NAD-dependent protein deacetylase OS=Clostridium sp. (strain SY8519) GN=cobB PE=3 SV=1
----------------------------------------EDIVFFGGAGVSTESGVPDFRSKDGLYNQYRPEYLLSHSCLMNEPKV---YFEYHRQKMD
TRKIEPNNAHRYLAALERTG-KLDAIVTQNIDGLHQKAGSRNVCEIHGSALRNYCVRCGKTYP-ADYFEPVPHC-ACG--GMIRPDITLYEEGLPAVRHA
VEAIAGADMLIIGGTSLTVYPAASYIDY-FR-GKYLVIINRDELNIRKN-TLVIHEKIGEVFTRVA-------------
>tr|W3ANP4|W3ANP4_9FIRM NAD-dependent protein deacetylase, SIR2 family OS=Lachnospiraceae bacterium JC7 GN=UYO_1422 PE=4 SV=1
----------------------------------------HSIVFFGGAGVSTESGVPDFRSKDGLYNQYQPEYLLSHSCLVLEPEV---YFEFHRQKMD
TRNIEPNNAHKYLAALEKTG-KLKAVVTQNIDGLHQKAGSKEVYEIHGSALRNYCMSCGKKYP-TDHFSPVPHC-ECG--GVIRPDITLYEESLPEVRKS
INAIASADMLIIGGTSLTVYPAASYINY-FE-GKYLVIINRDELSIRRSQTLVINDKIGEVFTRLA-------------
>tr|R7NAG3|R7NAG3_9FIRM Silent information regulator protein Sir2 OS=Eubacterium sp. CAG:76 GN=BN774_01927 PE=4 SV=1
----------------------------------------NSIVFFGGAGVSTESGIPDFRSKDGLYNQYEPEYLLSEECLHHKPKV---FFEFYRQKMD
ARNVKPNITHYMLARLEKLG-KLDKIITQNIDGLHQMAGSTNVIELHGATTRNYCEKCGKKYP-ADYFEAIPRCVECN--HMIRPDVTLYGEQLPAYESA
VEAIRKADMLIVAGTSLKVYPAAGLVWE-FA-GKHLVVMNKEPLDFKLDNDIEFNCAMGDVFRALD-------------
>tr|D2RNB5|D2RNB5_ACIFV NAD-dependent protein deacetylase OS=Acidaminococcus fermentans (strain ATCC 25085 / DSM 20731 / VR4) GN=cobB PE=3 SV=1
----------------------------------------DHIVFFGGAGVSTASGIPDFRSKDGLYNQYRPEYLLSHSCLVNEPKV---YFEFHRQKMD
TRKIQPNNAHKYLAALEKTG-KLDGIVTQNIDGLHQKAGSRKVYEIHGSALRNYCMSCGKRYP-SDYFEPIPHC-TCG--GVIRPDITLYEEMLPAVENA
VRAISRADLMIIAGTSLTVYPAASFINY-FH-GKRLVILNRDPLSVHMK-TLVITENMDKVFKALA-------------
>tr|R6L5F7|R6L5F7_9FIRM Silent information regulator protein Sir2 OS=Eubacterium sp. CAG:252 GN=BN564_00872 PE=4 SV=1
----------------------------------------DNIVFFGGAGVSTESGIPDFRSKDGLYNQYEPEYLLSEECLHHKPKV---FYEFYRQKMD
ARGIKPNITHYVLAKLEQMG-KLKAVVTQNIDGLHQLAESKNVIELHGATTRNYCERCHKKYP-SDYYEAIPVCTECG--GMVRPDVTLYGEQLPAYENA
VKAIKQADMFIVAGTSLKVYPAAGLVWD-FK-GSHLVVLNREALDFKLNEDIEYTGSMGDVFAELD-------------
>tr|E0RXE9|E0RXE9_BUTPB SIR2 family protein OS=Butyrivibrio proteoclasticus (strain ATCC 51982 / DSM 14932 / B316) GN=bpr_I0238 PE=4 SV=1
----------------------------------------DNIVFFGGAGVSTESGIPDFRSKDGLYNQYQPEYLLSHSCLVYEPQV---YYEFHRQKMD
TRNIEPNDAHKYLAALEKLG-KLKGIVTQNIDGLHQKAGSVAVYEIHGSALRNYCMSCGKEYP-EDYFEPIPRC-SCG--GIIRPDITLYEEGLPQVDGA
IKAISAAEMLIIGGTSLTVYPAASFINY-FR-GKYLVIINESEISVRAAETLVIKEKIGKVFRELA-------------
>tr|B7C7W5|B7C7W5_9FIRM NAD-dependent protein deacetylase OS=Holdemanella biformis DSM 3989 GN=cobB PE=3 SV=1
--------------------------------------ESNNIVFFGGAGVSTESNIPDFRSDNGLYKKYPAEIMLSHSFYLSHPKE---FFDFYFNQMI
YSDAKPNKAHLALSKLEQMG-KLKAIVTQNIDGLHQMAGSKHVYELHGSVLRNTCTHCQAKYS-LEDMKGIPRCPKCG--AIIKPDVVLYEEGLDTLYSA
IHAIEKADLLIVGGTSLVVYPAAGLINY-FH-GKHLVLINRDTTNMDS-KDLVIHDSIGKVLDDSL-------------
>tr|R7A3X6|R7A3X6_9FIRM NAD-dependent protein deacetylase OS=Firmicutes bacterium CAG:308 GN=cobB PE=3 SV=1
--------------------------------------ESNNIVFFGGAGVSTESNIPDFRSDNGLYK-YPAEVMLSHSFYESNPKE---FFEFYFNQMI
YKDAKPNKAHLALAQLEKQG-KLKAVITQNIDGLHQAAGSKTVYELHGSVLRNTCTGCHEKYT-LDQLEGIPRCPKCN--HIIKPDVVLYEEGLDTMMNA
IQAIAQADLLIVGGTSLVVYPAAGLIRY-FQ-GKHLVLINKDKTSMDH-IDLVIHDSIGKVLSESV-------------
>tr|K9EEL1|K9EEL1_9LACT Uncharacterized protein OS=Alloiococcus otitis ATCC 51267 GN=HMPREF9698_00328 PE=4 SV=1
----------------------------------------DRIVFFGGAGVSTASGIPDFRSSEGLYMQVPAEEIISDRFFANHPKE---FFDFYFKNLV
FEGAQPNYAHTYIADLEKRG-KSVAVVTQNIDGLHEKAGSQEVYKLHGSTLDNYCLDCQQYYA-YSDQLGVPRCPKDG--AIVRPDIVLYGEQLDTLQAA
IYQISQADLLVILGTSLVVYPAAGLVDY-FQ-GDKLAVVNKTTIHPRR-TGLIIQEDINKVFKQLT-------------
>tr|R9LPU5|R9LPU5_9FIRM NAD-dependent protein deacetylase OS=Firmicutes bacterium M10-2 GN=cobB PE=3 SV=1
--------------------------------------NSSSIVFFGGAGVSTESHIPDFRSDTGLYK-YLAEQMLSHSFYVKHPKE---FFDFYFNEMI
YEDAVPNKAHLALTKLEKQG-KLKAIVTQNIDGLHQKAGSVNVLELHGSVMRNYCTQCKKSFT-LDEIQGIPRCDNDQ--AIIKPDVVLYEEGLDIIYEA
VNAISHADTLIVGGTSLVVYPAAGLIQY-FQ-GKNLVLINKESTPMDS-QTLVIHDSIGKVLDEAV-------------
>tr|R5ZDH2|R5ZDH2_9FIRM NAD-dependent protein deacetylase OS=Firmicutes bacterium CAG:536 GN=cobB PE=3 SV=1
--------------------------------------ESDNIVFFGGAGVSTESNIPDFRSDNGLYKKYPAEQMISHSFFVSNPKE---FYEFYFNQMI
FPDAKPNKAHLALAKLEKMG-KLKAVVTQNIDGLHQKAGSKNVFELHGSVLKNTCVKCHSHYT-LEEMAGIPVCPTCQ--GIIKPDVVLYEEGLDTIYGA
VQAIEQADLLIVGGTSLVVYPAAGLLQY-FH-GKHLVLINRDATSMDH-QDLVIHDSIGQVFSQVV-------------
>tr|R6D0Y0|R6D0Y0_9FIRM Transcriptional regulator Sir2 family OS=Ruminococcus sp. CAG:579 GN=BN718_00556 PE=4 SV=1
--------------------------------------ISKKIVFFGGAGVSTESGIPDFRSPNGLYRDVPPEVILSHTYFEEHPKE---FFKFYREKML
YLTASPNRAHKKLAELEAAG-KDITVVTQNVDGLHQKAGSKKVLELHGSVYRNYCTGCGQFYN-VNFANPVPECSICG--GIIKPDVVLYEESLRTIVDT
VKAMEEADMLIVAGTSLTVYPAASFLNY-FR-GRYTVVVNLSRHERED-RDIAFHQRVGDVFSRID-------------
>tr|A0A087D5F4|A0A087D5F4_9BIFI NAD-dependent deacetylase OS=Bifidobacterium scardovii GN=BSCA_1607 PE=4 SV=1
----------------------------------------KKIAVLTGAGISTSAGIPDFRGPDGVWTK---MSVYDIDAFLADKEY---SWRWQK----
-ENAQPGTAHKALVTLERAG-MLTLLATQNFDALHEKAGNDVIVNLHGTIGTSHCMKCHAKYDTADIMAPDPHCHRCN--GLIKTDVVYFGEALPAMEKS
MKRAREADEFWVIGSTLEVFPAASLVPVAA-QGVPITIMNMGRTQY-RLATRLIHEDIAVALPRLV-------------
>tr|A0A087BT87|A0A087BT87_9BIFI Sir2-type regulatory protein OS=Bifidobacterium minimum GN=BMIN_1136 PE=4 SV=1
----------------------------------------THIAVLTGAGISTSAGIPDFRGPQGVWTK---MSVYDIDAFLSDQQY---SWRWQK----
-ENAEPGDAHKALVRLEKAG-MLSLLATQNFDALHEKAGNDLIVNLHGTIGTSHCMRCHAEYRTSQIMDPDPHCHRCN--GLIKTDVVYFGEALPAMEKS
MRAVVKSDALWVIGSTLEVFPAASLVPIAA-QGVPITIMTMGRTQY-RLASRLIRDDIATALPELV-------------
>tr|X8H0B2|X8H0B2_9FIRM NAD-dependent protein deacetylase OS=Shuttleworthia sp. MSX8B GN=cobB PE=3 SV=1
--------------------------------------GASKIVFFGGAGVSTESGLKDFRSQDGLYHEYPPETILSHSFFMRQPED---FYRFYFDKLL
VGVIEPNAAHKKLAELEAAG-KLSAVITQNIDGLHQRAGSRKVFELHGSIHRNHCMSCGHFFD-GEYLAPVPHCPVCG--GIIKPDVVLYEEGLDVINGA
LEAIEEADLLIIGGTSLTVYPAAGFIRY-YR-GNHLVLINRDATGQDE-LDLVIHGSIGEILGKIR-------------
>tr|F4LPJ4|F4LPJ4_TREBD NAD-dependent protein deacetylase OS=Treponema brennaborense (strain DSM 12168 / CIP 105900 / DD5/3) GN=cobB PE=3 SV=1
--------------------------------------ESRNIVFFGGAGVSTESGIPDFRSTDGLYRQYPPETILSRSFFDAHPAE---FYRFYRAKMI
VPDAKPNAAHFKLAELEAAG-KLGAVITQNIDGLHQAAGSKTVYELHGSVLRNYCMKCGAFYP-VRALDGIPRC-TCG--GIIKPDVVLYEEGLDTVDAA
VRAISCADTLIIGGTSLVVYPAASLIDY-FH-GRRLVLINKSATAADG-RDLCITDRIGAVLDAVH-------------
>tr|U2K008|U2K008_TRELE NAD-dependent protein deacetylase OS=Treponema lecithinolyticum ATCC 700332 GN=cobB PE=3 SV=1
--------------------------------------TSSSIVFFGGAGVSTESGIPDFRSTGGLYNQYPPETILSRSFFNAYPKE---FYRFYRSKML
FPQAKPNAAHTKLAQLENAG-KLKAVITQNIDGLHQAAGSKTVYELHGSVLRNYCMNCGAFYD-VDYIKTVPVCIKCG--GTVKPDVVLYEESLNILSKS
AAAVAAADTLIIGGTSLAVYPAASLIQY-FK-GAHLVLINKGETAADG-SDLIIRSPIAEVFSQLK-------------
>tr|U2UMW2|U2UMW2_9FIRM NAD-dependent protein deacetylase OS=Mitsuokella sp. oral taxon 131 str. W9106 GN=cobB PE=3 SV=1
--------------------------------------GSSRMVFFGGAGMSTESGIPDFRSADGIYSQFRPEEMVSHTFLLQHPQA---FFDFLFGKMI
FLDARPNDGHRALASLEARG-KLCAVITQNIDGLHQMAGSKAVYELHGSLMRWSCTECGRCYF-LAYLQPIPRCRECG--GMVRPDVVLYEEPLDVIEHS
VKAIRQADTLIVGGTSLAVYPAAGLLDY-FH-GDHLVVINRTATKADQ-SSLLIREPIGEVLRAAG-------------
>tr|I0GW20|I0GW20_SELRL NAD-dependent protein deacetylase OS=Selenomonas ruminantium subsp. lactilytica (strain NBRC 103574 / TAM6421) GN=cobB PE=3 SV=
--------------------------------------DSKRVVFFGGAGMSTESGIPDFRSADGIFNQFRPEEMASHSFLVNYPEE---FFEFYRNRMM
FMNAEPNDGHRALAKLEEMG-ILRAVVTQNIDGLHQLAGSRTVYELHGSSLRWPCMKCGKVYP-MEFLRPIPHCSDCG--GVVRPGVVLYEEGLDVVENA
MRAIREADTLIVGGTSLVVYPAAGMIDY-FR-GRHLVLINKSETKADA-SDLIIREPIGKTLAAAV-------------
>tr|A0A0H3DXA8|A0A0H3DXA8_BACA1 NAD-dependent protein deacetylase OS=Bacillus atrophaeus (strain 1942) GN=cobB PE=3 SV=1
----------------------------------------KRIVVLTGAGMSTESGIPDFRSAGGIWTE---MEAMSRDYFERYPRL---FWPKFK----
-ERFEPNEGHVYLAELEKEG-KQVDIFTQNIDGLHKKAGSRHVYELHGSIQTAACPACGASYDLSHL-LDVPQCTACS--TVLKTDVVLFGDIVQHFDTL
YEKLSQADLLLVIGTSLEVAPARFVPEEASRIGMKQILINLEPTYC-DLFDLVIHRKIGEFAKELS-------------
>tr|M4KWN7|M4KWN7_BACIU NAD-dependent protein deacetylase OS=Bacillus subtilis XF-1 GN=npdA PE=3 SV=1
----------------------------------------QRIVVLTGAGMSTESGIPDFRSAGGIWTE---MEAMSLDYFLSHPRL---FWPKFK----
-ESFEPNEGHLLLAELEKQG-KQIDIFTQNIDGLHKKAGSRHVYELHGSIQTAACPACGARYDLPHL-LEVPECTACG--TVLKTDVVLFGDAVMHFDTL
YEKLDQADLLLVIGTSLEVAPARFVPEDASLIGMKKVIINLEPTYC-SLFDMVIHQKIGEFARSLG-------------
>tr|M5PEV3|M5PEV3_9BACI NAD-dependent protein deacetylase OS=Bacillus sonorensis L12 GN=cobB PE=3 SV=1
----------------------------------------RRITVLTGAGMSTESGIPDFRSAGGLWTE---MEAMSRDYFERYPKL---FWPKFK----
-ASFQPNAGHLYLAELEKRG-KDVRVFTQNIDGLHVKAGSRHVYELHGSIQTARCPKCGAGYGLEHL-LEVPRCSRCG--FILKTDVVLFGDPVQHFDTL
FDILADSDLLLVIGTSLEVAPVRFVPEEAHLIGLKKAMINLEKTPY-HLFDVVIHRKIAEFTKEIS-------------
>tr|W7RVR4|W7RVR4_BACLI NAD-dependent protein deacetylase OS=Bacillus licheniformis S 16 GN=cobB PE=3 SV=1
----------------------------------------ERITVLTGAGMSTESGIPDFRSAGGIWTE---MEAMSRDYYERYPKL---FWPKFK----
-ETYQPNDGHLYLAELAKSG-KDVRVFTQNIDGLHLKAGSRHVYELHGSIQTATCPKCGARYGLDHI-LEVPRCNRCG--FILKTDVVLFGDAVQHFDTL
FEALNESDLLLVIGTSLEVAPVRFVPEEAHLIGLKKAMINLDQTPY-HLFDIVIHQKIAEFVRKLN-------------
>tr|A0A0F5KXD6|A0A0F5KXD6_9BACI NAD-dependent protein deacetylase OS=Bacillus sp. TH008 GN=cobB PE=3 SV=1
----------------------------------------QCITVLTGAGMSTESGIPDFRSAGGIWTE---MEAMSRDYYERYPKL---FWPKFK----
-ETFQPNAGHLYLAGLEKRG-KDVRVFTQNIDGLHIKAGSRRVYELHGSIQTAVCPKCGARYGLEHI-LDVPRCSRCG--FILKTDVVLFGDAVQHFDTL
FESLDESDLLLVIGTSLEVAPVRFVPGEAHLIGLKKIMINLDDTPF-HLFDVVIHRKIAEFVKEIS-------------
>tr|A0A0M4FHL6|A0A0M4FHL6_9BACI NAD-dependent deacetylase OS=Bacillus gobiensis GN=AM592_02520 PE=4 SV=1
----------------------------------------DHITVLTGAGMSTESGIPDFRSAGGIWAE---MEAMSRSYFEQYPKR---FWPKFK----
-GNHEPNKGHLYLAELEKQG-KSIEIFTQNIDGLHKKAGSRYVYELHGSIQTGTCPKCQTKYDLSHL-LDVPRCTRCG--FIVKTDVVLFGDMVHHLDTL
FQTIEKTDLLLVIGTSLEVAPVNLVPQEAHYIGLNKALVNLEPTAY-DLFDLVIHEKIGELVSDMK-------------
>tr|A0A0A2T7U5|A0A0A2T7U5_9BACI NAD-dependent deacetylase OS=Pontibacillus yanchengensis Y32 GN=N782_17920 PE=4 SV=1
----------------------------------------NRIAVLTGAGVSTASGIPDFRSAGGIWEQ---EYYMSSGYFQEHPVD---FWKKYK----
-DNYQPNKVHSFLREFEDKG-KEVTIITQNVDGLHEKAGNSRVIEYHGSLTTATCPTCGTQYGLSHV-MDTPRCTTCN--DILKPDIVLFGDPITKHDEA
EAIIDQADVLLVLGTSLFVMPFNFLPDYAKYQNLPTILINREQTAK-ELFDYVVHDDLTQAIEEIK-------------
>tr|A0A023DGR3|A0A023DGR3_9BACI NAD-dependent protein deacetylase OS=Geobacillus caldoxylosilyticus NBRC 107762 GN=cobB PE=3 SV=1
----------------------------------------DVIAVLTGAGMSTESGIPDFRSENGIYAQ---EYYLSEYYFEKDPVD---FWRRFK----
-RNFAPNDGHRFLRQLEEMG-KKVTILTQNIDGLHKKAGSTNVIELHGTLQTATCPECGEKHDLAFI-NDVPRCERCN--EILKPDVVLFGGLVPRIEEA
FAAAAESDLLIAMGTSLEVAPVNQIPFYVATQVTYKVIINKTPTRM-DVFDLVIHGGIGETVAKVR-------------
>tr|C5D284|C5D284_GEOSW NAD-dependent protein deacetylase OS=Geobacillus sp. (strain WCH70) GN=cobB PE=3 SV=1
----------------------------------------DKITVLTGAGMSTESGIPDFRSENGIYAQ---EHYISEYYFETHPVD---FWHKFK----
-RNFAPNQGHLFLKHLEDMG-KKVTILTQNIDGLHKKAGSSRVIELHGTLQTATCPKCQTKYDLAFV-NDVPRCEQCN--EILKPDVVLFGGMVHRFEEA
LEAAYDSDLLIAMGTSLEVTPVNQIPFYVSTERAHKVIINKTPTRM-YLFDIVIHVGIGETVAKVQ-------------
>tr|I3E886|I3E886_BACMT NAD-dependent protein deacetylase OS=Bacillus methanolicus MGA3 GN=cobB2 PE=3 SV=1
----------------------------------------KTITIFTGAGMSTESGIPDFRSDNGIYSQ---ENYISEYYFEKNPKD---FWSKFK----
-RNFDPNEGHLFLKELEEMG-KNVTILTQNIDGLHHKAGNSDIIELHGTLQTATCPKCKTKYDLKFI-NVIPRCNQCN--FILKPDVVLFGGMVQHFEEA
LNKAYKSDLFIAMGTSLEVYPVNQIPVYLNSAEIKKAIINKSPTKM-YLFDIVIHEGIGDTVAKIK-------------
>tr|A0A0F6BMB0|A0A0F6BMB0_GEOS0 NAD-dependent protein deacetylase OS=Geobacillus sp. (strain Y4.1MC1) GN=cobB PE=3 SV=1
----------------------------------------KKITVLTGAGMSTESGIPDFRSENGIYAQ---EYYISEYYFKNHPVD---FWHKFK----
-RNFSPNQGHLFLKWLEDIG-KKVVILTQNIDGLHEKAGSTNVVELHGTLQTATCPKCQAKYDLAFV-NDVPRCVRCN--EILKPDVVLFGGMVQRFEEA
LQAADGSDLLIAMGTSLEVAPVNFIPSYVAAEHIRKVLVNKTPTKM-DVFDIVLHAGIGETVAKVQ-------------
>tr|A0A0L7MLS3|A0A0L7MLS3_9BACI NAD-dependent protein deacetylase OS=Bacillus methylotrophicus GN=cobB PE=3 SV=1
----------------------------------------ERIVVLTGAGMSTESGIPDFRSAGGIWTE---MEAMSREYFERRPRE---FWPKFK----
-QSYEPNAGHTYLADLEKRG-KQVDIFTQNIDGLHKKAGSSSVYELHGSIQTAACPRCGARYGLSHL-LEVPECTACG--TVLKTDVVLFGDLVQHFETL
YEKLDKADLLLVIGTSLEVAPARFVPEDAGRIGLKQVIINLEPTYC-HLFDLVIHEKIGEFAKRIS-------------
>tr|S5Z4W1|S5Z4W1_9BACI NAD-dependent protein deacetylase OS=Geobacillus sp. JF8 GN=cobB PE=3 SV=1
----------------------------------------DTIAVLTGAGMSTESGIPDFRGENGIYAH---EHYLSEYYFEKDPID---FWRRFK----
-QGFAPNDGHRFLRWLEDIG-KRVVILTQNIDGLHVKAGSTHVIELHGTLRTATCPSCGKTYELAFV-NDVPRCNECR--AILKPDVVLFGGFVPHIEEA
FAKAAESDLFLAMGTSLEVAPVNQIPFYVAAEATRKVLMNKTATRM-GIFDLVIYGGIGETVAGVR-------------
>tr|G8N5V9|G8N5V9_GEOTH NAD-dependent protein deacetylase OS=Geobacillus thermoleovorans CCB_US3_UF5 GN=cobB PE=3 SV=1
----------------------------------------NTIAVLTGAGMSTESGIPDFRSENGLYAQ---EYYLSEYYYKKDPVD---FWRRFK----
-RGFAPNDGHRFLRWLEEMG-KTVTILTQNIDGLHTKAGSTNVIELHGTLQTATCPSCGNKYDLSFI-NEVPRCEKCQ--TIVKPDVVLFGGLVPRMEEA
FAAAAASDLLLAMGTSLEVAPVNQIPFYVAAEATRKVLINKTATRM-GMFDLVIYGGIGKTVASVR-------------
>tr|A4ING8|A4ING8_GEOTN NAD-dependent protein deacetylase OS=Geobacillus thermodenitrificans (strain NG80-2) GN=cobB PE=3 SV=1
----------------------------------------NTIAVLTGAGMSTESGIPDFRSENGIYAQ---EYYLSEHYYQKNPVD---FWRRFK----
-RDFAPNAGHRFLRWLEDIG-KTVVILTQNIDGLHTKAGNTNVIELHGTLQTATCPSCGKTYDLAFV-NDVPCCGECG--TILKPDVVLFGGLVPHIEEA
FARAAESDLLLAMGTSLEVAPVNQIPFYVAAEATRKVLINKTATRM-GIFDLIIYGGIGETVAAVR-------------
>tr|A0A084HD89|A0A084HD89_9BACI NAD-dependent deacetylase OS=Bacillus sp. SJS GN=AS29_05230 PE=4 SV=1
----------------------------------------NVISVMTGAGVSTESGIPDFRSSQGLWTE---TEVMSRSYFERNPKS---FWRYFK----
-DGHQPNKGHSFLRDLESMG-KEVRIFTQNVDGLHQKAGSRHVYNMHGSIQSAECPKCKTSYGLDYI-HEVPRCSACD--FILKPDVVLFGDTVQHMEEI
YHTVDRSELLLVMGTSLEVYPVNQIPKDFRYRDKKMVLINREPTRI-HVFDLVIHASIGETLEQAE-------------
>tr|A0A0C2HR74|A0A0C2HR74_9STAP NAD-dependent protein deacetylase OS=Salinicoccus roseus GN=cobB PE=3 SV=1
----------------------------------------RRTVFFTGAGVSVKSGIPDFRSMGGLFDEHSPEYLLSREHLEDDPES---FIRFYRKRLM
LADKAPNIVHDFIAHEERTG-RSLGVITQNIDGLHHDAGSRNVDELHGSLNRFYCISCSREYP-KQDMADIAHC-ACG--SVIRPDIVLYGEMLDVINSA
IDKLATADTLVVMGSSLLVNPAAFLINY-FN-GSHLVIINRDDTPFDE-EDLVINEDMTEVIETIY-------------
>tr|A0A0M2SRP4|A0A0M2SRP4_9STAP NAD-dependent protein deacetylase OS=Salinicoccus sp. SV-16 GN=cobB PE=3 SV=1
----------------------------------------RRIVFFTGAGVSVKSGIPDFRSMGGLFDEHSPEYLLSADHLNDNPES---FIEFYRKRLL
LADKAPNIVHEYIAELEKEG-RSAGVITQNIDGLHSDAGSRHVDELHGTLNRFYCVSCSRQFT-KETMTDMKHC-SCG--GVLRPDIVLYGEMLNAIFSA
IDKISNADVLVVLGSSLVVNPAAAMTGY-FN-GEHFIIINKDPTPFDR-DSLVFNRDMTEIIESIQ-------------
>tr|E8SHC7|E8SHC7_STAPH NAD-dependent protein deacetylase OS=Staphylococcus pseudintermedius (strain HKU10-03) GN=cobB PE=3 SV=1
----------------------------------------ERIVFFTGAGVSVASGVPDFRSMGGLFDEYSPEYLLSTDYLEDDPIG---FMRFCHKRLL
LEDKLPNPVHKWIAELEQRQ-HSLGVITQNIDGLHSDAGSQHVDELHGTLNRFYCPNCQQQYT-KNEMTQLIQCQQCG--HVIRPDIVLYGETLDTMSNA
LQKITHADTLIVLGSSLVVQPAAGLISH-FQ-GEHLVIINKDTTPYDQ-QHLVIHNDMVSIVEELT-------------
>tr|G5JH10|G5JH10_9STAP NAD-dependent protein deacetylase OS=Staphylococcus simiae CCM 7213 GN=cobB PE=3 SV=1
----------------------------------------NNIVFFTGAGVSVASGIPDFRSVGGLYDDFSPEYMLSHDYLETDPLG---FMAFCHSRLL
FADKKPNVVHQWIAKLEQQG-KSLGVITQNIDGLHSDAGSQHVDELHGTLNRFYCLSCDQQYT-KEEVNNLYHCEQCG--HAIRPDIVLYGEMLDTIYNS
LSKINKADTLVVLGSSLVVQPAAGLISN-FN-GQHLVIINRDTTPYDN-DTLVINDDMLNVVNRLE-------------
>tr|A0A0A8HM22|A0A0A8HM22_STAHY NAD-dependent deacetylase OS=Staphylococcus hyicus GN=SHYC_00755 PE=4 SV=1
----------------------------------------SKIVFFTGAGISVASGIPDFRSVGGINEKHAPEYILSVDYLNDDPQG---FMSFCFDYLL
FADKTPNIVHNWIAQLEREG-RSLGVVTQNIDSLHSDAGSHKVDELHGTMNRFYCTHCHAQYT-KSNLAHLHQCDQCG--GHIRPAIVLYGEMLDTLMRA
MYKISDADTLIVLGSSLIVQPAAGLVSN-FA-GKHLVIINQDPTPYDN-QDLVIHEDMVNIIQELN-------------
>tr|A0A069F1Y2|A0A069F1Y2_STACR NAD-dependent protein deacetylase OS=Staphylococcus chromogenes MU 970 GN=cobB PE=3 SV=1
----------------------------------------NKIVFFTGAGISVASGIPDFRSVGGLNDKYAPEYMLSADYLHEDPQG---FIDFYYQYLL
FADKAPNAVHQWIAQLEAEG-RALGVITQNIDGLHSDAGSQHVAELHGTLNRFYCTECETQYT-KSYLEQLHRCEQCG--GVIRPDIVLYGEMLDTLIYA
MQLINEADTLIVLGSSLVVQPAAGLVGN-FN-HGRLVIINRDATPYDQ-QDLVIHEDMVQVIEALT-------------
>tr|U7PGM1|U7PGM1_STASI Uncharacterized protein OS=Staphylococcus simulans UMC-CNS-990 GN=SSIM_00835 PE=4 SV=1
----------------------------------------NKIVFFTGAGISVASGIPDFRSVGGLYEALSPEYLLSHDYLQDNPVG---FMDFCHEYLL
FADKKPNNVHEWIAQLEKEN-RSLGVITQNIDGLHSDAGSENVDELHGTLNRFYSINNNDEYS-KPYIDHLRNSEQDG--SPIRPDIVLYGEMLDTIMSA
ISKIKQADTLVVLGSSLVVQPASGLISN-FE-GENLVIINKDVTPYDS-DDLVIHDDMKHVINELN-------------
>tr|A0A0M5N824|A0A0M5N824_9STAP NAD-dependent deacetylase OS=Staphylococcus schleiferi GN=SSCHL_0144 PE=4 SV=1
----------------------------------------HKIVFFTGAGVSVASGIPDFRSIGGLYDEYSPEYLLSADYLHSDPIG---FMDFCHQYLL
FADKAPNPVHQWIAQLEKKK-RSLGVITQNIDGLHTDAGSHHVDELHGTLNRFYTVEGNETYT-KEEIANLYRSNSNG--SPIRPDIVLYGEALDTLLNA
IFKIKAADTLVVLGSSLVVQPAAGLISE-FE-GENLVIINRDSTPYDS-RNLVIHDDMVGVIEALQ-------------
>tr|A0A0D6DFN2|A0A0D6DFN2_STAAU NAD-dependent protein deacetylase OS=Staphylococcus aureus subsp. aureus GN=cobB PE=3 SV=1
----------------------------------------HRITFFTGAGVSVASGVPDFRSMGGLFDELSPEYLLSRDYLEDDPEG---FINFCHKRLL
FVDTKPNIVHDWIAKLERNQ-QSLGVITQNIDGLHSDAGSQHVDELHGTLNRFYCNACHKSYT-KSDIDTLKHCDNCG--GAIRPDIVLYGEMLDTIIRA
LNKIEHADTLVVLGSSLVVQPAAGLISN-FK-GDNLIIINKDRTPYDS-DTLVIHDDMVSVVKSLI-------------
>tr|L7WQF6|L7WQF6_STAWS NAD-dependent deacetylase OS=Staphylococcus warneri (strain SG1) GN=A284_03495 PE=4 SV=1
----------------------------------------SNIVFFTGAGVSVASGVPDFRSMGGLFDEYSPEYLLSRDYLQDDPKG---FINFCHKRLM
YIDKSPNIVHHWIAQLEHDE-KSLGVITQNIDGFHSDAGSKYVDELHGSLNTFYCNQCHHQYS-KKDIEQLKQCDICG--ATIRPDIVLYGEMLDVIMRA
LQKIENADTLVVLGSSLVVQPAAGLISN-FK-GDNLIIINKDYTPYDA-HSLVINDDMINVVSELN-------------
>tr|B9DIE3|B9DIE3_STACT NAD-dependent protein deacetylase OS=Staphylococcus carnosus (strain TM300) GN=cobB PE=3 SV=1
----------------------------------------NKITFFTGAGISVASGIPDFRSIGGLYDELSPEYLLSTEYFQNDPDG---FINFCHEYLL
FADKKPNIVHDWIAELENEG-KSLGVITQNIDGLHTDAGSEEVDELHGTLNRFYCIECDQDYS-KSEIENLRHCENCG--GPIRPDIVLYGEMLNTIFSA
LNKIREADTLVVLGSSLVVQPAAGLISN-FE-GKNLVIINLDSTPYDH-DDLVIHEDMVKVIEALK-------------
>tr|A0A085UFK6|A0A085UFK6_9STAP NAD-dependent deacetylase OS=Staphylococcus agnetis GN=SAGN_04050 PE=4 SV=1
----------------------------------------HKIVFFTGAGISVASGIPDFRSIGGINDAYTAEYILSADYLRDDPAG---FIDFCYQYLL
FADKKPNRVHQWIAELEAEG-RSLGVITQNIDGLHSDAGSQRVDELHGTMNRFYCTRCDATFT-KSYLAQLRHCDQCG--GHIRPDIVLYGEVLDTLMRA
MFKMNDADTLIVLGSSLVVQPAAGFVSQ-FN-HGNMIIINREPTPYDH-LDLVIQEDMVKVIAALE-------------
>tr|A0A033UE30|A0A033UE30_STAAU NAD-dependent deacetylase OS=Staphylococcus aureus C0673 GN=V070_02523 PE=4 SV=1
----------------------------------------QNITFFTGAGISVASGIPDFRSLGGLYDQYSPEYLLSTDYLQSDPEG---FMDFCFQYLL
FTDKQPNIVHQWIAQLEKDH-RSLGVITQNIDGLHSNAGSLNTDELHGTLNRFYCTKCHQIYT-KSYIDHLHHCESCD--HTIRPDIVLYGETLNTIFNA
LNKIREADTLVVLGSSLLVQPAAGLISN-FE-GQNLVIINKDETPYDA-TNIVIHDDMVAVVQELL-------------
>tr|A0A0G3W3J1|A0A0G3W3J1_STACP NAD-dependent protein deacetylase OS=Staphylococcus capitis subsp. capitis GN=cobB PE=3 SV=1
----------------------------------------NNIVFFTGAGVSVASGIPDFRSMGGLFDEQSPEYLLSVDHLNDDKES---FIDFYHKRLL
IADKKPNIVHQWIAALEREH-KSLGVITQNIDGLHSDAGSRHVDELHGTLNRFYCIKCYNEYS-KSQMEHIRYCEKCG--QIIRPDIVLYGEMLNTVFRA
LGKIQKADTLVVLGSSLVVQPAAGFVSE-FK-GDNLIIINRDRTPYDQ-SDLVIHDDMTEVVEKIM-------------
>tr|A0A0Q1CWG5|A0A0Q1CWG5_STAHA NAD-dependent deacetylase OS=Staphylococcus haemolyticus GN=SHTS_01680 PE=4 SV=1
----------------------------------------NNIVFFTGAGVSVASGIPDFRSMGGLFDEYSPEYLLSVDHLNDNKES---FIDFYHKRLL
VADKKPNIVHEWIAELEREG-KSLGVITQNIDGLHEDAGSQNIDEIHGTLNRFYCIKCGKEYT-KSYMEELRYCESCG--EVIRPDIVLYGEMLDTVFRA
LDKIQKADTVIVLGSSLVVQPAAGFISN-FT-GDNLVIINRDKTPYDR-KDLVIHNDMTEVVEEVF-------------
>tr|A0A0M2NX13|A0A0M2NX13_STACC NAD-dependent protein deacetylase OS=Staphylococcus cohnii subsp. cohnii GN=cobB PE=3 SV=1
----------------------------------------NSITFFTGAGISVASGIPDFRSIGGLYEEYPPEYLLSEAYFQNDPEG---FINFCHDYLL
FADKKPNIVHQWIAQLEQHQ-QSLGVITQNIDGLHSDAGSSHTDELHGTLKRFYCINCEQKYS-KQYIHNLRHCETCG--SAIRPDIVLYGEMLNTIFDA
LHKIKSADTLVVLGSSLVVQPAAGLISN-FE-GQNLVIINRDPTPYDS-DNLVIHDDMVSVINELC-------------
>tr|A0A0D0RS54|A0A0D0RS54_STAGA NAD-dependent deacetylase OS=Staphylococcus gallinarum GN=SH09_01605 PE=4 SV=1
----------------------------------------NKIVFFTGAGISVASGIPDFRSVGGLYDEFSPEYLLSDDYLKSDPSG---FINFCHQYLL
FADKKPNSVHQWIAQLEQDK-RSLGVITQNIDGLHADAGSTHVDELHGTLNRFYCTHCNHEYS-KNDITNLRACETCG--EPIRPDIVLYGEMLNTIFNA
LHKIKSADTLVVLGSSLVVQPAAGLISN-FE-GENLIIINRDATPYDH-DNLVINDDMVTVINKLT-------------
>tr|A0A0E1VBJ0|A0A0E1VBJ0_STAEP NAD-dependent protein deacetylase OS=Staphylococcus epidermidis W23144 GN=cobB PE=3 SV=1
----------------------------------------NQIVFFTGAGISVASGIPDFRSMGGLYDEQSPEYLLSIDHLHDNKES---FINFYHERLL
IADKKPNIVHQWIAQLENQQ-KSLGVITQNIDGLHEDAGSHNIDELHGSLNRFYCINCYEEYS-KSYMTHLKYCEKCG--NVIRPDIVLYGEMLNTVFKA
LDKIQHADTLIVLGSSLVVQPAAGFVSE-FK-GDNLVIINRDATPYDH-TSLVIHDDMTSVIEEIV-------------
>tr|K9AQ35|K9AQ35_9STAP NAD-dependent protein deacetylase OS=Staphylococcus massiliensis S46 GN=cobB PE=3 SV=1
----------------------------------------KKITFFTGAGVSVASGIPDFRSMGGLFDEYSPEYLLSSNYLQDDPEG---FTNFYHKRLL
LSDKKPNVVHDWMAQLEKEG-RSLGVITQNIDGLDADAGSQNIDELHGTLNRFYCISCHKEYE-KSYIEDLRQCEACG--SPIRPDIVLYGEMLNTVMNA
ISKISEADTLIVLGSSLIVQPAAGLISN-FQ-GKHLVIINKAETPYDT-QDLVIHDDMAEVVSALR-------------
>tr|A0A0E3D4F7|A0A0E3D4F7_STASA NAD-dependent protein deacetylase OS=Staphylococcus saprophyticus GN=cobB PE=3 SV=1
----------------------------------------NQITFFTGAGVSVASGVPDFRSMGGLFDEYAPEYLLSAEYLQNDPEG---FVDFYHKRLL
LADKQPNVVHEWIAQLEHHQ-RSLGVITQNIDGLHTDAGSANVDELHGTLNRFYCIQCEHKYD-KATMAHLRHCETCG--SPIRPDIVLYGEMLDTISNA
IQKIQEADTLVVLGSSLVVQPAAGLISY-FE-GQHLIIINKDATPYDR-DDVVIHDDMVDVVNAIR-------------
>tr|H0DFF0|H0DFF0_9STAP NAD-dependent protein deacetylase OS=Staphylococcus pettenkoferi VCU012 GN=cobB PE=3 SV=1
----------------------------------------ERIVFFTGAGVSVASGIPDFRSMGGLFDEYSPEYLLSRDYLNADPEG---YINFTHKRLL
MSDKAPNPVHEWIAQLEDEG-RALGVITQNIDGLHSDAGSHNVDELHGTLNRFYCLNCDAEYT-KEEMETLKACERCG--GPIRPDIVLYGEMLNTISRA
LNKLTSADTLVVLGTSLVVQPAAGLVSN-FQ-GDHFVIINRDETPYDN-SDIVIHDDMVDVVEALN-------------
>tr|J9HF67|J9HF67_9STAP NAD-dependent protein deacetylase OS=Staphylococcus sp. OJ82 GN=cobB PE=3 SV=1
----------------------------------------NKITFFTGAGVSVASGVPDFRSMGGLFDEYAPEYLLSTDYLQDDPVR---FVDFYHKRLL
LADKQPNLVHQWIAQLEQDK-RSLGVITQNIDGLHSDAGSLNVDELHGTLNHFYCIDCHKAYF-KYYMKHLRECEVCG--SPIRPDIVLYGELLNTIYNA
LDKIKEADTLVVLGSSLVVQPAAGLISK-FQ-GQNLVIINKDHTPYDN-HTLVIHDDMVKVVNELG-------------
>tr|A0A068E4K1|A0A068E4K1_STAXY NAD-dependent protein deacetylase OS=Staphylococcus xylosus GN=cobB PE=3 SV=1
----------------------------------------RRITFFTGAGVSVASGVPDFRSMGGLFDEYSPEYLLSTNYLQDDPEG---FVDFYHKRLL
LADKQPNTIHQWIAQLEKDH-QSLGVITQNIDGLHSDAGSLNVDELHGTLNQFYCVDCFNEYD-KTYMEHLRHCESCG--SIIRPDIVLYGEMLNTIFNA
INKIETSDTLIVLGSSLVVQPAAGLISN-FK-GKNLIIINRDATPYDH-NDLVINEDMVSVISMLN-------------
>tr|A0A0Q9XYB7|A0A0Q9XYB7_9STAP NAD-dependent deacetylase OS=Staphylococcus sp. NAM3COL9 GN=ACA31_12900 PE=4 SV=1
----------------------------------------NNITFFTGAGVSVASGVPDFRSMGGLFDEYAPEYLLSTDYLQDDPVG---FVNFYHKRLL
IADKQPNLVHQWIAQLEQNK-RSLGVITQNIDGLHTDAGSSNVDELHGTLNQFYCIECHNEYF-RNYMAHLRECETCG--NPIRPDIVLYGELLNTIYNA
LNKINEADTLVVLGSSLVVQPAAGLISN-FK-GQNLVIINRDPTPYDN-HTLVIHDDMVKVIKDLE-------------
>tr|E6MAE1|E6MAE1_STALU NAD-dependent protein deacetylase OS=Staphylococcus lugdunensis M23590 GN=cobB PE=3 SV=1
----------------------------------------QRIVFFTGAGVSVASGIPDFRSSGGLYDDYAPEYLLSINYFEDDPKG---FMNFVHQRLL
FADKTPNPVHYWIAELENKG-KSLGVITQNIDGLHEDAGSKNIDEIHGTLNRFYCLNCGKKYT-KSYIEDLIYCEDCG--KAIRPDIVLYGEMLDAVFSA
LNKIQEADTVIVLGSSLVVQPAAGFISN-FT-GDNLVIINRDATPYDH-RDLVIHDDMTKVVKDVL-------------
>tr|A0A095WQR3|A0A095WQR3_9ACTO Uncharacterized protein OS=Actinomyces sp. S6-Spd3 GN=HMPREF1627_06575 PE=4 SV=1
----------------------------------------ASTVFFGGAGVSTESGIPDFRGANGFYFQIPLEQVLSIDFFSVHPEA---YWEWFREV--
HKPVAPNGAHRALASLESSG-LLECVITQNIDGLHQRAGSRTVWELHGNWEHLLCTNCGAGYP-FSSPELVPTCPRCH--GQLRPDIVMYGEALNVITSA
VQAIAHADLLIVAGTSLVVYPAAGLLNY-FS-GSHLVLMNATPTNADA-DDLIIRDPIAQSFEAVI-------------
>tr|E6KUE5|E6KUE5_9ACTO NAD-dependent deacetylase OS=Actinomyces sp. oral taxon 180 str. F0310 GN=HMPREF9006_1847 PE=4 SV=1
----------------------------------------PSTVFFGGAGVSTESGIPDFRGANGFYFQIPLETVLSIDFFSRHPEA---YWQWFDEV--
YRPVEPNGAHRALASLEAAG-RLDAVITQNIDGLHQRAGSRAVWELHGNWERLVCPGCGAVQP-LGELRPVPSCPSCG--SHLRPDIVMYGEALDVIEAA
VTAISRASVLIVAGTSLVVYPAAGLIDY-FS-GDHLVLMNATPTSADA-HDMIIREPVAHTFDQVM-------------
>tr|J2YVJ1|J2YVJ1_9ACTN Transcriptional regulator, Sir2 family OS=Atopobium sp. ICM58 GN=HMPREF1138_1292 PE=4 SV=1
----------------------------------------PSTVFFGGAGVSTESGIPDFRGANGFYFQIPLETVLSIDFFAKHPEA---YWEWFHEI--
YRPVNPNGAHRALAALEAAG-RLDAVVTQNIDGLHQRAGSRTVWELHGNWERLVCTRCGTVAA-LADVTPVPACPSCG--GQMRPDIVMYGESLDVIEAA
VSAIARASTLIVAGTSLVVYPAAGLINY-FS-GDHLVLMNATPTLADA-HDLIVRDPVARTFDQVM-------------
>tr|V8C5M5|V8C5M5_9FIRM NAD-dependent protein deacetylase OS=Ruminococcus lactaris CC59_002D GN=cobB PE=3 SV=1
--------------------------------------ESSRIVFFGGAGVSTESGIPDFRSADGIYHQYSPEQVVSHSFFIKYPEA---FYEFYKEKMM
MLDAKPNPAHLKLAELEAAG-KLQAVVTQNIDGLHQAAGSKKVYELHGSIHRNYCMKCGKFYD-AEYKKGVPHCS-CG--GEIKPDVVLYEEGLDTMDGA
VRAIGSADTLIIGGTSLVVYPAAGFIDY-FR-GKHLVVINKSSTEKAV-RELSIAAPIGEILGSIQ-------------
>tr|R7B5W2|R7B5W2_9ACTN Sir2 family protein OS=Eggerthella sp. CAG:298 GN=BN592_00564 PE=4 SV=1
--------------------------------------DPKSVVFFGGAGVSTESGIPDFRSVKGIFNEYPPEVIVSHSFFEAHPDV---FYEFYRAKMV
HEDAKPNQAHKKLAELEQQG-ILRSVITQNVDGLHQAAGSKRVHELHGSIHRNYCMKCGKRYG-LDAMEGVPYCE-CG--GIIRPDVVLYEEALDVIQAA
VEDIAQAETLIIAGTSRVVYPAAGLVEF-FN-GKHLIVINRDPSALDK-TDHCLTMNVGEAFDF---------------
>tr|R6WJL4|R6WJL4_9FIRM NAD-dependent protein deacetylase OS=Dorea sp. CAG:317 GN=cobB PE=3 SV=1
--------------------------------------DSENIVFFGGAGVSTESGIPDFRSADGIYHQYSPEQIVSHSFFMRNTEA---FYEFYKEKMM
FLEAKPNAAHLKLAQLEAEG-KLKAVITQNIDGLHQAAGSKNVWELHGSIHRNYCRKCGKFYD-ASYKNGVPRCE-CG--GLIKPDVVLYEEGLDVIEHS
IRAICEADTLIIGGTSLVVYPAAGFIDY-FR-GKHLVVINKSATAKEV-RELTIAAPIGEVMKGLK-------------
>tr|A5KNZ2|A5KNZ2_9FIRM NAD-dependent protein deacetylase OS=Ruminococcus torques ATCC 27756 GN=cobB PE=3 SV=1
--------------------------------------ESESIVFFGGAGVSTESGIPDFRSADGIYHQFSPEQVVSHTFFMRYPEA---FYEFYKEKMM
ILDAKPNAAHLKLAELERAG-KLTAVVTQNIDGLHQLAGSKRVYELHGSIHRNYCMNCGKFYD-AQYKKGVPKCS-CG--GVVKPDVVLYEEGLDTIRGA
VEAIASADMLLIGGTSLVVYPAAGFIDY-FR-GSRLAVINKSETAKNI-RELTISAPIGEILSRIK-------------
>tr|V2Z8S7|V2Z8S7_9FIRM NAD-dependent protein deacetylase OS=Catonella morbi ATCC 51271 GN=cobB PE=3 SV=1
--------------------------------------DSKSIVFFGGAGVSTESGIPDFRSADGLYHQYSPEQIISHSFFLRYPEA---FYEFYKEKMM
CLTAKPNSAHIKLAELEKAG-KLLAVVTQNIDGLHQEAGSKKVFELHGSIHRNYCMKCRKFYD-AEFKNGIPRCE-CG--GIVKPDVVLYEEGLDVIERA
LMAISSADTLIIGGTSLVVYPAAGFVDY-FH-GKHLVVINKSDTGRNL-NELVINAPIGEIMKGIN-------------
>tr|G9WP40|G9WP40_9FIRM NAD-dependent protein deacetylase OS=Oribacterium parvum ACB1 GN=cobB PE=3 SV=1
--------------------------------------ESENIVFFGGAGVSTESGIPDFRSEDGLYHEYPPERILSHSFFLQYPEI---FYQFYKEKML
YLDAPANPAHKKLAELEEAG-KLKAVVTQNIDGLHQKAGSKVVYELHGSIHRNYCLHCGKFYS-AEFQEGVPKCS-CG--GVIKPDVVLYEESLDLIQDA
IRAIAHADTLIIGGTSLVVYPAAGFIDY-FR-GKHLVLINKAETGKTV-GDLIINAPIGEVLGKIQ-------------
>tr|E6LQK7|E6LQK7_9FIRM NAD-dependent protein deacetylase OS=Lachnoanaerobaculum saburreum DSM 3986 GN=cobB PE=3 SV=1
--------------------------------------DSKAIVFFGGAGVSTESGIPDFRSADGLYHQYSPEQVVSHSFFMKYPKQ---FYEFYKERMM
CLDAKPNAAHNKLSELESLG-KLKAVVTQNIDGLHQAAGSKIVYELHGSIHRNYCMKCGKFYD-AKYKNEVPYCT-CG--GMIKPDVVLYEEGLDVINSA
IRAIASADTLIIGGTSLVVYPAAGFIDY-FR-GKHLVVINKSDTAKAV-SNLSINAPIGEIMSGIE-------------
>tr|G9WRS5|G9WRS5_9FIRM NAD-dependent protein deacetylase OS=Oribacterium asaccharolyticum ACB7 GN=cobB PE=3 SV=1
--------------------------------------ESAHIVFFGGAGVSTESGIPDFRSEDGLYHEYPPEQIISHSFFLTKPEV---FYRFYKEKML
CLDAEPNAAHRKLAELEQAG-KLKAVVTQNIDGLHQKAGSKIVYELHGSIHRNYCLSCHKFYP-AKFKEGVPHCS-CN--GVIKPDVVLYEESLDTIEDA
VTAITNADTLIIGGTSLVVYPAAGFIDY-FR-GKHLVLINKAETGRAV-RELSIHAPIGEILEKIV-------------
>tr|F7JY99|F7JY99_9FIRM Uncharacterized protein OS=Lachnospiraceae bacterium 2_1_58FAA GN=HMPREF0991_02112 PE=4 SV=1
--------------------------------------ESSNIVFFGGAGVSTESNIPDFRSADGIYHQYSPEEVVSHSFYEKHPKA---FFEFYREKMM
VLDAKPNAAHLKLAELENAG-KIKAVITQNIDGLHQAAGSQVVYELHGSIHRNYCEKCGRFYD-AGFKAGVPVCS-CG--GRIKPDVVLYEEALDIIEKA
VRAISQADMLIIGGTSLVVYPAAGFIDY-FR-GKYLVVINKSEMAKAV-RNLSISAPIGEILGRIK-------------
>tr|K0XK82|K0XK82_9FIRM NAD-dependent protein deacetylase OS=Lachnoanaerobaculum sp. OBRC5-5 GN=cobB PE=3 SV=1
--------------------------------------DSTNIVFFGGAGVSTESGIPDFRSADGLYHQYSPEQVVSHSFFMKYPEV---FYEFYKDKMM
CLDAKPNAAHNKLSELESSG-KLKAVVTQNIDGLHQKAGSKTVYELHGSIHRNYCMKCQKSYD-ANYKNGIPYCE-CG--GMIKPDVVLYEEGLDVINAA
IRAIASADTLIIGGTSLVVYPAAGFIDY-FQ-GKHLVVINKSETGKAV-NELSINAPIGEIMSGII-------------
>tr|F7JKY4|F7JKY4_9FIRM NAD-dependent protein deacetylase OS=Lachnospiraceae bacterium 1_4_56FAA GN=cobB PE=3 SV=1
--------------------------------------ESSRIVFFGGAGVSTESGIPDFRSADGIYHQYSPEEVVSHSFFVKHPEA---FYEFYKEKMM
ILDARPNPAHLKLAELERAG-KLSAVVTQNIDGLHQAAGSRQVYELHGSILRNYCMDCHTFYD-AEYKNGIPRCEKCG--GMIKPDVVLYEEGLDTISGA
VRAISEADMLIIGGTSLVVYPAAGFIDY-FH-GKYLVLINKSETARDV-RNLAIAAPIGSVMEKIR-------------
>tr|R5XHC1|R5XHC1_9FIRM NAD-dependent protein deacetylase OS=Firmicutes bacterium CAG:212 GN=cobB PE=3 SV=1
--------------------------------------ESQNIVFFGGAGVSTESGIPDFRSADGIYHQYSPEQVVSHSFFIQHTEA---FYEFYKEKMM
MLDAKPNAAHRKLAELEMAG-KLKAVVTQNIDGLHQAAGSKTVYELHGSIMRNYCMDCHEFYD-AEYKSGIPRCKKCG--GIIKPDVVLYEEGLDTIQGA
VNAISQADMLIIGGTSLVVYPAAGFIDY-FN-GKYLAVINKSETGRAV-RNLTISAPIGEVMEKIF-------------
>tr|V6DKW0|V6DKW0_9LACO NAD-dependent protein deacetylase OS=Lactobacillus salivarius cp400 GN=cobB PE=3 SV=1
--------------------------------------ESSNIVFFGGAGVSTESGIPDFRSEQGIYNTYPPEQILSHSFFMKNPEK---FYDFYRSTMI
YESAKPNLAHLGLAKLEKQG-KLKAIVTQNIDGLHQLAGSKTVYELHGSIHRNYCMKCGKFYP-LSTTEGVPQCKECG--GIIKPDVVLYEEGLDIINNS
IKAIKKADMLIVGGTSLNVYPAASFVNY-YD-GNKLILINKSKTPYDR-YDLLIHDSIGKVFNEII-------------
>tr|F3B682|F3B682_9FIRM NAD-dependent protein deacetylase OS=Lachnospiraceae oral taxon 107 str. F0167 GN=cobB PE=3 SV=1
--------------------------------------DSKNIVFFGGAGVSTESGIPDFRSADGLYHQYSPEQIVSHSFFMRYPEV---FYEFYKEKMI
CLDAKPNAAHIKLAELEKAG-RLKAVVTQNIDGLHQAAGSKTVYELHGSIHRNYCMKCHKFYD-AKFKEGIPICE-CG--GKIKPDVVLYEEGLDTIEGA
VKAISSADTLIIGGTSLVVYPAAGFIDY-FR-GKHLVVINKSDTGRAV-NELFINAPIGEIMDKII-------------
>tr|R6PBZ7|R6PBZ7_9FIRM NAD-dependent protein deacetylase OS=Ruminococcus sp. CAG:55 GN=cobB PE=3 SV=1
--------------------------------------ESNRIVFFGGAGVSTESNIPDFRSATGIYHQYSPEQVVSHSFFMKYPEA---FYEFYKEKMM
ILGAKPNAAHLKLAELEQAG-KLQAVVTQNIDGLHQAAGSRKVYELHGSIHRNYCMKCGKFYD-AEYKNGIPRCS-CG--GMIKPDVVLYEEGLDTIQGA
VEAISSADMLIIGGTSLVVYPAAGFIDY-FH-GKHLVVINKSETARTV-RELVISASIGEVLGAIH-------------
>tr|E9RWP3|E9RWP3_9FIRM NAD-dependent protein deacetylase OS=Lachnospiraceae bacterium 4_1_37FAA GN=cobB PE=3 SV=1
--------------------------------------ESQKIVFFGGAGVSTESGIPDFRSADGLYQQYTPEQVVSHSFFVRNPEA---FYEFYKEKMM
FLEAEPNPAHEKLAQLEHVG-KLTAVITQNIDGLHQKAGSEQVLELHGSIHRNYCQKCGKFYD-AATKEGIPRCI-CG--GIIKPDVVLYEEGLDVIRRA
IRAISEADMLIIGGTSLVVYPAAGFIDY-FR-GKYLVVINKSETARTV-EDLCIRRPIGEVFAQIQ-------------
>tr|R5D8F8|R5D8F8_9FIRM NAD-dependent protein deacetylase OS=Dorea sp. CAG:105 GN=cobB PE=3 SV=1
--------------------------------------DSDRIVFFGGAGVSTESNIPDFRSADGLYHQYTPEQIVSHSFFMHNPEG---FYEFYKEKMM
YLNAKPNAAHKKIAELEAAG-KLTAVITQNIDGLHQAAGSKNVLELHGSIHRNYCMECGRFYD-AAYKNGIPHCE-CG--GMIKPDVVLYEEGLDVIQKS
IRAISEADMLIIGGTSLVVYPAAGFIDY-FH-GKHLVVINKSETARSV-GDLTIAAPIGEIMDAIV-------------
>tr|R9JZ30|R9JZ30_9FIRM NAD-dependent protein deacetylase OS=Lachnospiraceae bacterium M18-1 GN=cobB PE=3 SV=1
--------------------------------------ASSNIVFFGGAGVSTESNIPDFRSAGGIYHQYSPEQVVSHSFFVEHTDT---FFEFYKEKMM
ILDAKPNPAHLKLAELEEAG-KLSAVVTQNIDGLHQAAGSKSVYELHGSIMRNYCMDCHTFYD-AEYKNGVPRCEKCG--GLVKPDVVLYEEGLDVIQGA
IRAITDADMLIIGGTSLVVYPAAGFIDY-FR-GKYLAVINKSETGRTV-RDLSISAPIGQIMSRIE-------------
>tr|R9MI54|R9MI54_9FIRM NAD-dependent protein deacetylase OS=Lachnospiraceae bacterium 3-2 GN=cobB PE=3 SV=1
--------------------------------------DSERIVFFGGAGVSTESNIPDFRSADGLYQQYSPEQIVSHTFFVHRTES---FYEFYKEKMM
FLDAKPNAAHKKLAELEEAG-KLTAVITQNIDGLHQAAGSKNVLELHGSIHRNYCQSCRKFYD-AAYKGGIPKCS-CG--GTIKPDVVLYEEGLDVINRS
IKAISEADMLIIGGTSLVVYPAAGFIDY-FR-GKHLAVINKSTTAREV-GKLTIAAPIGEIMEKIE-------------
>tr|R6LZK4|R6LZK4_9FIRM NAD-dependent protein deacetylase OS=Firmicutes bacterium CAG:170 GN=cobB PE=3 SV=1
--------------------------------------ASDNIVFFGGAGVSTESGIPDFRSTDGLYHQYPPETILSHTFFYQHTEY---FYRFYREKML
PLEAEPNAAHRALAALERAG-KLRAIVTQNIDGLHQKAGSKNVYELHGSIWRNYCTKCGKSYS-AEFR-GVPHCA-CG--GLIKPDVVLYEEGLDTIKGA
VRAIAEADVLIVGGTSLTVYPAAGLIRY-YG-GNRLVLINRDETPYDG-YNLIFREPIGQVLGQCV-------------
>tr|R7I2X6|R7I2X6_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. CAG:411 GN=cobB PE=3 SV=1
--------------------------------------ESNNLVFFGGAGVSTASNIPDFRSSDGLYSKFSPEEAVSHTFLMRHPEE---FYEFYKQNLI
YPDAKPNACHEALVKLEKMG-KLKAIVTQNIDGLHQAAGSKVVYELHGSVHRNYCIQCGTRYDNAAYLQGVPKCEKCG--GEVRPDVVLYEEGLDVIRGA
VHAISNADTLIIGGTSLVVYPAAGLINY-FN-GKHLIQINKTKTKADS-QDLTINDDIAKVMKEAV-------------
>tr|N2APF7|N2APF7_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. ASF502 GN=cobB PE=3 SV=1
--------------------------------------ESSKIVFFGGAGVSTESGIPDFRSADGIYHQYSPEQVVSHSFFMAHTDA---FFEFYKEKMM
ILDAEPNPAHLKLAELEQAG-KLSAVVTQNIDGLHQAAGSKAVYELHGSIMRNYCMDCHVFYD-AAYKGSVPRCEKCG--GLVKPDVVLYEEGLDVIEGT
VRAISNADMLIIGGTSLVVYPAAGFIDY-FQ-GKYLVVINKSETGRAV-RDLTISAPIGQIMGGIE-------------
>tr|B0NFP9|B0NFP9_CLOSV NAD-dependent protein deacetylase OS=[Clostridium] scindens ATCC 35704 GN=cobB PE=3 SV=1
--------------------------------------DSGNIVFFGGAGVSTESNIPDFRSADGLYLQYSPEQIVSHSFFVSRTED---FYEFYKNKMM
FLDAKPNPAHCKLAQLETAG-KLTAVITQNIDGLHQAAGSRNVLELHGSILRNYCQRCGKSYD-AAYKNGIPKCS-CG--GTIKPDVVLYEESLDTVDKS
IRAISEADTLIIGGTSLIVYPAAGFIDY-FR-GRHLVVINKSATAKEV-GELTIAAPIGEVMGRIE-------------
>tr|F0YTI0|F0YTI0_9CLOT NAD-dependent protein deacetylase OS=Clostridium sp. D5 GN=cobB PE=3 SV=1
--------------------------------------ESSHIVFFGGAGVSTESNIPDFRSADGIYHQYSPEQVVSHSFFMQYTEA---FYDFYKEKMM
ILDAKPNPAHLKLAELERAG-KLKAVITQNIDGLHQAAGSKNVYELHGSIHRSYCMKCHRFYD-AQFKAGIPRCE-CG--GIIKPDVVLYEEGLDTIQGA
VNAIAEADTLIIGGTSLVVYPAAGFIDY-FR-GRHLVVINKSETAKAV-RELSISAPIGQILERIQ-------------
>tr|C0C0D1|C0C0D1_9FIRM NAD-dependent protein deacetylase OS=[Clostridium] hylemonae DSM 15053 GN=cobB PE=3 SV=1
--------------------------------------ESSRIVFFGGAGVSTESNIPDFRSADGLYRQYSPEQIVSHSFFVKNTED---FYEFYREKMM
FLDAEPNPAHLKLAELEAAG-KLTAVVTQNIDGLHQAAGSRNVLELHGSIHRNYCRKCGKFFD-ASYKHGVPKCE-CG--GLIKPDVVLYEESLDVISRS
VQAISEADTLIIGGTSLIVYPAAGFIDY-FS-GRHLVVINKSATAKEV-GDLTIAAPIGEVLGQIE-------------
>tr|A0A0G3HDX8|A0A0G3HDX8_9CORY NAD-dependent protein deacetylase OS=Corynebacterium uterequi GN=cobB PE=3 SV=1
--------------------------------------HSSETVFFGGAGVSTESGIPDFRSAAGLYAQLPPEYLLSHECLVNYPEQ---FYDFHRTKLL
HPQARPNPAHLALAELESRG-RLRSVITQNIDGLHQLAGSRTVRELHGSVHHYTCVGCHQPYG-LTQ--VVPACPECG--EMIRPDVVLYGEALDVVAAA
VADIQAAEVLIVGGTSLNVYPAAGLLRY-FR-GTKLVLINLEGTPFDA-ADLVIRDRIGAVFGEVM-------------
>tr|S3Y7H8|S3Y7H8_9ACTN NAD-dependent protein deacetylase OS=Propionibacterium sp. oral taxon 192 str. F0372 GN=cobB PE=3 SV=1
--------------------------------------DARSAVFFGGAGVSTASGIPDFRSAAGLYVTREPEYLLSHECLIAEPAE---FFTFHRTHLV
HPEAKPNRAHLALARLEDSG-HLAAVVTQNIDGLHQAAGSRTVHELHGSVERNHCVQCGRAID-LAD--VIPVCPDCG--GMVRPDVVLYGEGLDVIDAS
IRAIQQADVLIVGGTSLNVYPAAGLIRY-YR-GHRLVLINLTETPADK-GDLVIHSPIDEVLDTVV-------------
>tr|K1MKF8|K1MKF8_9LACT Uncharacterized protein OS=Facklamia hominis CCUG 36813 GN=HMPREF9706_00402 PE=4 SV=1
----------------------------------------SHLVFFGGAGVSTASGIPDFRSSKGIYMKCRAEEILSHDFFEAHPEI---FFDFYFKHLI
YPQAKPNPAHQYLATLEQQG-KSVMVITQNIDGLHQRAGSQNVIELHGTTLDNYCLKCGQHYS-LKEERGVPRCPIDQ--AIVRPNIVLYQESLDTIMSS
IEAMSQADLLIVAGTSLNVYPAASFIQY-FN-GKSCAVINQSPIRNLP-PSFVFNDRIESVFSRLK-------------
>tr|E4KP46|E4KP46_9LACT Transcriptional regulator, Sir2 family OS=Eremococcus coleocola ACS-139-V-Col8 GN=HMPREF9257_1332 PE=4 SV=1
----------------------------------------QNLVFFGGAGVSTASGIPDFRSANGVYSQMSPEEIISHDFFKQYPAE---FYDFYFKHLV
YPEAKPNVVHKYLAQLEARG-KDLTIVTQNIDGLHQAAGSQKVVELHGSVHRNYCLACGRTYN-YENVLGIPRCPFDG--GLVRPDVVLYQEQLDAMLAA
MQAISQADMMIVAGTSLVVYPAAAFIQY-FQ-GQDLAVINKTPLKIRT-EVLDYMGDMKDIFQQLH-------------
>tr|A0A0R2HX32|A0A0R2HX32_CARDV NAD-dependent deacetylase OS=Carnobacterium divergens DSM 20623 GN=IV74_GL001783 PE=4 SV=1
----------------------------------------QKIVFFGGAGVSTESGIPDFRSADGLFNQVTPEEIVSHSFLKKHPQL---FFDYYFKHLI
YPSAKPNPAHAYLAALEQQD-KSVTVITQNIDGLHQVAGSQKVLELHGSVQHNHCELCQKKYS-LNEMRGIPRCDADN--GIVRPDVVLYGEALEVIDQS
IQAIKEADLLIIAGTSLSVYPSSGLIDF-YQ-GEDLVLINKSSLSAES-QTLVIHQAVGELFQQLN-------------
>tr|F2I5H1|F2I5H1_AERUA Transcriptional regulator, Sir2 family OS=Aerococcus urinae (strain ACS-120-V-Col10a) GN=HMPREF9243_1368 PE=4 SV=1
----------------------------------------DRIVFFGGAGVSTASGIPDFRSADGLFMQVSAEEIISHSFFEKYPQI---FFDYYFDHLV
YPDAKPNACHRYLADLEAKG-KEVAIVTQNIDGLHQEAGSQKVYELHGNVWDNYCLKCKRHYR-TEDEKGIPRCSFDQ--AIVRPNVVLYEEALDEILGA
VRAIEQADLMIVAGTSLRVYPAAGLIDY-FN-GSYLAVINKTKIQVDR-KTLVFEDSLTKVFKALD-------------
>tr|F8FKJ3|F8FKJ3_PAEMK NAD-dependent protein deacetylase OS=Paenibacillus mucilaginosus (strain KNP414) GN=npdA PE=3 SV=1
--------------------------------------LSSNIVFFGGAGTSTESGIPDFRSAQGLFETHAPEEMLSRDFFLSEPEE---FYRFYRTHMI
HAQAEPNAAHQALALLEKEG-RLKAVITQNIDGLHQKAGSERVLELHGSVHRNYCMDCRKFFP-LEALQPVPHCDACG--GIIKPDVVLYQEGLDILSAA
VEAIEAADMLIVAGTSLRVYPAAGLIRY-YS-GSKLVLINKSATPYDS-SNYLVQDSIGKVLSTMA-------------
>tr|A0A0F5R1Y0|A0A0F5R1Y0_9BACL NAD-dependent protein deacetylase OS=Paenibacillus sp. D9 GN=cobB PE=3 SV=1
--------------------------------------DSRRIVFFGGAGTSTESGIPDFRSADGLYEQYLPEEILSRDFFMEHPAD---FYAFYRTHMV
YPEALPNAAHRALARLEQEG-RLTAVVTQNIDGLHQLAGSRSVLELHGSVHRNYCMDCGLKYP-LSALRPVPLCTACE--GIVKPDVVLYQENLDLLDRA
AFEIEQADTLIVGGTSLTVHPAAGLVSL-YR-GDKLIIVNRTPTPLDD-YNYISDGNVGDVLGSLY-------------
>tr|R5FNX6|R5FNX6_9ACTN Uncharacterized protein OS=Eggerthella sp. CAG:1427 GN=BN494_00965 PE=4 SV=1
--------------------------------------PKGGMVFFGGAGVSTESGIPDFRSSDGLFMQIPPEQIVSRSFFEAHPAD---FYDFYFNHMI
FPDVEPNQAHRKLAELEQEG-ILSAVITQNVDGLHQKAGSKNVFELHGSSLKNYCCSCRKQFT-FEEVAGVPRCPECG--GIIRPDVVLYEEGLSVLVGA
MKAISQAALMVVAGTSLVVYPAAGLLQY-FK-GSHLAIVNLQPTAADR-NDLCISAKVGEVFDF---------------
>tr|F7UW53|F7UW53_EEGSY Putative uncharacterized protein OS=Eggerthella sp. (strain YY7918) GN=EGYY_23570 PE=4 SV=1
--------------------------------------PSGGMVFFGGAGVSTESGIPDFRSADGVFAQCPPEQMVSRSFFDAHPAA---FYDFYCDRML
ALNAQPNQAHRKLAELEKAG-TLRAVVTQNIDALHQKAGSQQVYELHGSVLRNFCMGCGAAYS-VEQLEGVPRCPTCG--GIVKPDVVLYEETLDTLKGA
MQAIAEASFLVIAGTSLAVYPAAGLIDG-FH-GSHLAIINRTPTPRDR-YDLCLTANVGEAFDF---------------
>tr|R7CI24|R7CI24_9ACTN NAD-dependent protein deacetylases SIR2 family OS=Cryptobacterium sp. CAG:338 GN=BN613_00403 PE=4 SV=1
--------------------------------------KKGGMVFFGGAGVSTESGIPDFRSSDGLFMQIPPEQVVSHSFFMQYPEQ---FFDFYFNHMI
FPEVKPNQAHRKLAELEQEG-ILSSVITQNVDGLHQKAGSNKVLELHGSSLENYCVKCKKRFS-LEEMAGVPRCPECG--GIVRPDVVLYEEGLNVLQAA
IKEISRADLMVVAGTSLVVYPAAGLLEF-FS-GSHLVIVNLQPTSSDR-QDLCIPARVGEVFDF---------------
>tr|A0A0H4KG49|A0A0H4KG49_9BACI NAD-dependent deacetylase OS=Bacillus endophyticus GN=BEH_06375 PE=4 SV=1
----------------------------------------DTITFFTGAGMSTESGLPDFRSSNGLYKQ---TDIVSLDFYEKDPVL---FWTLFK----
-DNYVPNKGYHYISKLQEKG-KNIRVITQNIDGLHYDSGHESVYEIHGSIKKAHCRSCYREYDLEYL-NDCPKCKECG--EILKPNVVLFGDPIQQFEEA
VRDALQSDLFFVLGSSLEVGPVNQIPLIVKEHDAKLIIINREETRF-SLFDYVFHINISDAFQHIL-------------
>tr|A0A0A5G1F5|A0A0A5G1F5_9BACI NAD-dependent deacetylase OS=Pontibacillus litoralis JSM 072002 GN=N784_03515 PE=4 SV=1
----------------------------------------NHIVILTGAGVSTASGIPDFRSTDGIWEQ---EYYMSADYFFKDPVD---FWNKYK----
-QQYGPNDVHTFLKQLENNN-KEISIITQNVDGLHAQAGNKHVVEYHGSLRTATCPSCGANYDLNYI-LETPTCVKCG--DILKPDIVLFGDAITEHDKA
EAIIDQADFLLVLGTSLFVMPFNFLPEYASMQNVPTALINGEPTLK-RLFDYVIHDDLSKVVEQMK-------------
>tr|A0A0A5FW85|A0A0A5FW85_9BACI NAD-dependent deacetylase OS=Pontibacillus marinus BH030004 = DSM 16465 GN=N783_18700 PE=4 SV=1
----------------------------------------NHIAVLTGAGVSTASGIPDFRSADGIWEQ---EDYMSNEYFRHNPIE---FWAKYK----
-SNYQPNAVHYFLKELEDEG-KEVSVITQNVDGLHLEAGNQRTIEYHGTLKTASCPTCNTTYDHEFM-METPRCTTCG--DVLKPDIVLFGDPITEHDRA
EAMIDQADLLLVLGTSLFVMPFNFLPDYAKYSNIPTAIINREATSK-YMFDYVIHGDLTEVIEELK-------------
>tr|U1X4F4|U1X4F4_ANEAE Putative NAD-dependent deacetylase OS=Aneurinibacillus aneurinilyticus ATCC 12856 GN=HMPREF0083_02108 PE=4 SV=1
----------------------------------------DRIVVLTGAGISTESGIPDFRSTEGIWTE---MDMMSTSYLRRNPDR---FWPAFK----
-DEIKPNRGHYFLAALEETG-KHITVVTQNVDGLHVAAGSGHVLEIHGTIKKAYCPSCVEQYDVSYV-KEVPRCIKCG--QVLRPAVVLFGDPVEGLEDA
FAAVENCDLFLTLGSSLEVTPVNYLPGAAASDAKMTAIINREPTQM-KYFDIVLHAEIGPTLSCIA-------------
>tr|A0A087AJN4|A0A087AJN4_9BIFI NAD-dependent protein deacetylase OS=Bifidobacterium cuniculi GN=BCUN_2194 PE=4 SV=1
----------------------------------------KQITVFTGAGISTSAGIPDFRGPDGVWTK---MQVYDLDAFLSDREY---SWRWQK----
-ENAKPGAAHYALVDLEEAG-MLKLIATQNFDALHEKAGSDKVVNLHGTIGTSHCMRCHHEYPTADIMGPDPHCHRCN--GLIKTDVVYFGEMLPAKERS
IRAAQQADELWVIGSTLEVFPAASIVPAAA-QGVPITIMNMGRTQY-SLADRLIHEDIAVALPQLV-------------
>tr|A0A086YWH4|A0A086YWH4_9BIFI NAD-dependent deacetylase OS=Bifidobacterium actinocoloniiforme DSM 22766 GN=AB656_06200 PE=4 SV=1
----------------------------------------KRIAVLTGAGISTSAGIPDFRGPDGVWTK---MQVYDLDAFLTNKRY---SWRWQK----
-ETAQPGVAHRALVKLEEAG-TLTLLATQNFDALHEKAGNELIVNLHGTIGSSHCMKCGAAYRTSEIMDPDPHCRRCG--GIIKTDVVYFGEALPAMEKS
LKEVRRADELWVIGSTLEVFPAASLVPAAA-QEVPITIMNMGRTQY-GLAQRLIRGPIQDALPELV-------------
>tr|A0A087BCY1|A0A087BCY1_9BIFI NAD-dependent deacetylase 2 OS=Bifidobacterium merycicum GN=BMERY_1949 PE=4 SV=1
----------------------------------------KKIAVLTGAGISTSAGIPDFRGPDGVWTK---MNVYDIDAFMANEEY---SWRWQK----
-ENAQPGTAHKALVKLEQAG-MLTLLATQNFDALHEKAGNSIIVNLHGTIGTSHCMKCHQKYDTSDIMDPDPHCHRCN--GLIKTDVVYFGEALPAMEKS
YRLATQADELWVIGSTLEVMPAASIVPVAA-QGVPITIMNMGRTQY-RLATRLIHDDIAVALPELV-------------
>tr|A0A087E9L9|A0A087E9L9_9BIFI Sir2-type regulatory protein OS=Bifidobacterium tsurumiense GN=BITS_1342 PE=4 SV=1
----------------------------------------RSIVVLTGAGISTSAGIPDFRGPDGVWTK---TSVYDIDAFLYDQEY---SWRWQK----
-ENAQPGVAHKALVDLENAG-MLSLLATQNFDALHEKAGNDLIVNLHGTIGTSHCMSCHAKYDTADIMAPDPHCRRCN--GLIKTDVVYFGEALPAMERS
MSAAAKADELWVIGSTLEVFPAASIVPVAA-QGVPITIMNMGSTQY-RLATNLIHEDIAVALPRLV-------------
>tr|I4LMC2|I4LMC2_GARVA Silent information regulator protein Sir2 OS=Gardnerella vaginalis 0288E GN=CGSMWGv0288E_01634 PE=4 SV=1
----------------------------------------NHIVALTGAGISTSAGIPDFRGPDGVWTK---MSVYDIDAFLSSEEY---SWRWQK----
-ENAQPGTAHKSLVKLEKAG-MLDLIATQNFDALHEKAGNDIVVNLHGSIGTSHCMSCHASYNTADIMRPDPHCRRCN--GLIKTDVVYFGEALPAMERS
AQAIMHASELWVIGSTLEVFPAASLVPLAA-RGVPITIMNLGATQY-YLAERVIREDIAKALPKLV-------------
>tr|D1NWI1|D1NWI1_9BIFI NAD-dependent deacetylase OS=Bifidobacterium gallicum DSM 20093 = LMG 11596 GN=BGLCM_0167 PE=4 SV=1
----------------------------------------KQIAVLTGAGISTSAGIPDFRGPDGVWTK---MSVYDIDRFLGNKEY---SWRWQK----
-ETAQPGAAHKALVDLEQAG-MLKLLATQNFDALHEKAGNSKIVNLHGTIGTSHCMTCHAKYDTAAIMDPDPHCRRCN--GLIKTDVVYFGEALPAMERA
LKAATEADELWVIGSTLEVFPAASVVPVAA-QGTPITIMNMGKTQF-YLADRLIREDIAVALPELV-------------
>tr|E6K2D5|E6K2D5_PARDN Transcriptional regulator, Sir2 family OS=Parascardovia denticolens DSM 10105 = JCM 12538 GN=HMPREF0620_1608 PE=4 SV=1
----------------------------------------YRIAVLTGAGISTSAGIPDFRGPEGVWTK---MNVYDIQSFMTSTEY---SWRWQK----
-ENARPGVAHQALVDLEKAG-LLSLLATQNFDGLHEKAGNAVIVNLHGTIASSHCMRCHKKYDTAEIMDPDPHCRRCN--GIIKTDVTYFGEALPAMEKS
QRLVEQADEFWAIGSTLEVFPAALLAPMAA-RGVPITIMNMGATQY-GLASRLIHEPIQEALPRLV-------------
>tr|W5IHR2|W5IHR2_SCAIO Uncharacterized protein OS=Scardovia inopinata F0304 GN=HMPREF9020_00002 PE=4 SV=1
----------------------------------------YKIAVLTGAGISTSAGIPDFRGPEGVWTK---MNVYDIQAFLTSKDY---SWRWQK----
-ENAQPGVAHQALVKLEKAG-LLTLLATQNFDGLHEKAGNHVIVNLHGTIASSHCMRCHKKYKTADIMDPDPHCTRCG--GLIKTDVTYFGEALPAMELS
SQRAQEADEFWVVGSTLEVFPAASLVPIAA-RGVPITIMNMGATQY-YLADRLIREPIEQALPQLV-------------
>tr|J0LLR0|J0LLR0_9BIFI Uncharacterized protein OS=Scardovia wiggsiae F0424 GN=HMPREF9156_00948 PE=4 SV=1
----------------------------------------YKIAVLTGAGISTSAGIPDFRGPDGVWTK---MDVYDIQAFLTSTEY---SWRWQK----
-ENAQPGIAHKALADLEKAG-MLSVLATQNFDGLHEKAGNSVIVNLHGTIATSHCMSCHKKYDTAEIMDPDPRCRRCN--GLIKTDVTYFGEALPAMEKS
MERVRQSDEFWVIGSTLEVFPAAMLAPVAA-RGIPITIMNMGETQF-PLAARLIREPIQDALPELV-------------
>tr|A0A077TPI9|A0A077TPI9_PLACH Transcriptional regulatory protein sir2 homologue, putative OS=Plasmodium chabaudi chabaudi GN=PCHAS_134840 PE=3 SV=1
----------------------------------------KYIVALTGSGTSAESNIPSFRGSNSIWSKY-PKIYGTI-GFWKYPEK---IWEVIK----
-DEIGLNPGHVALSKLENL-GYLKSIITQNIDGLHEESGNTKVIPLHGNIFEALCCTCNKTVQLNKIMLLPPEC-PCG--GIFKPNIVLFGEVISLLKEA
EDEITKCDLLLVIGTSSTVSTATNLCYFAS-KKKKIVEINIEKTYITNRMDYHLLAKFSELAN-LI-------------
>tr|W4IDG6|W4IDG6_PLAFA Uncharacterized protein OS=Plasmodium falciparum NF135/5.C10 GN=PFNF135_04713 PE=3 SV=1
----------------------------------------KHVVALTGSGTSAESNIPSFRGSSSIWSKY-PRIYGTI-GFWKYPEK---IWEVIR----
-DEIEINNGHVALSTLESL-GYLKSVVTQNVDGLHEASGNTKVISLHGNVFEAVCCTCNKIVKLNKIMLLPPEC-PCG--GIFKPNIILFGEVVSLLKEA
EEEIAKCDLLLVIGTSSTVSTATNLCHFAC-KKKKIVEINISKTYITNKMDYHVCAKFSELTK-VA-------------
>tr|W7A7L2|W7A7L2_9APIC Uncharacterized protein OS=Plasmodium inui San Antonio 1 GN=C922_01785 PE=3 SV=1
----------------------------------------TYIVALTGSGTSAESNIPSFRGANSIWSKY-PKIYGTI-GFWKAPEK---IWEVIR----
-DEIEMNPGHVALSTLENL-GYLKAVITQNIDGLHEESGNSRVIPLHGSVFEARCCTCRETIQLNKIMLLPPEC-PCG--GIFKPNVVLFGEVIPILKQA
EKEIEKCDLLLVIGTSSSVSTATNLCYYAH-RKKRIVEVNISKTYITNRMDYHVRAKFSELLA-IC-------------
>tr|L1JDT4|L1JDT4_GUITH Uncharacterized protein (Fragment) OS=Guillardia theta CCMP2712 GN=GUITHDRAFT_40776 PE=4 SV=1
--------------------------------------SSNNILVLTGAGVSVSAGIPDFRSSTGIYAFPRPSCMFDRNYFDANPKPFFNFAHELWP--G
--NFQPTPCHHFIAMLEQ-KHKLLRNYSQNIDTLEQKANIRRVINCHGSFATATCVSCGHRVEGKLDILRVAKCPPSF--GVLKPDIVFFGEALHFFSSL
REDLRLVDLVVVIGTSLRVAPVSEILGEVEASVP-AILINREVVGAPNQFDVELLGDCDAVVGELCCML----------
>tr|A9UP70|A9UP70_MONBE Uncharacterized protein (Fragment) OS=Monosiga brevicollis GN=1942 PE=4 SV=1
--------------------------------------QARNIIMVTGAGISTSCGIPDFRSPDGLYAYPQPEAMFDMRYFLQNPRPFFDFAKEIWP--G
--LFQPSPSHKFVKALET-RGQLRRDYTQNIDTLEQVAGISNIVQCHGSFNTASCILCKHQVTKEDQVFAIPLCPHRV--PVLKPDITFFREDLTFYEHL
ESDLDVCDLVIVMGSSLQVQPVSRIPDVVDDSVP-QILINREPLRHA-EFSAELLGSCD--------------------
>tr|E1R711|E1R711_SPISS Silent information regulator protein Sir2 OS=Spirochaeta smaragdinae (strain DSM 11293 / JCM 15392 / SEBR 4228) GN=Spirs_2222 P
--------------------------------------ESGNILVVTGAGISTSAGIIDFRSPGGLYSRPYPEAIFDIAYFHKNPAPFFRLSAELLL--A
--DIKPTPCHHFLVDLEA-KGKIGILVTQNIDMLHEKAGSKHVIECHGSYRTGRCLSCGKRFEYKGPLLKIPYCK--G--GIIKPDVVFFGESLSFMSLF
-YRRPKVDLLLVLGTSLTVQPVSSFALDYAPRIP-SILVNRDPTPYDGRFSYVHHGELDDFAQQ---------------
>tr|H0UM24|H0UM24_9BACT NAD-dependent protein deacetylase, SIR2 family OS=Jonquetella anthropi DSM 22815 GN=JonanDRAFT_0138 PE=4 SV=1
--------------------------------------ASRRAVAFTGAGVSTDAGLPDFRGPNGLYR--DASRLFDIDAFYEDPSYYYRFHRQLRK--I
LAGIRPTVTHRFLAQWEQ-SGRLAALVTQNFDGLHEAAGSKRVFPVHGTVATNTCLRCGRGFSAAEFLAEVPHC--CG--GVIKPDVVFFGESV-FLSES
FAAAEAADFMLVLGTSLTVAPACSVPALC---PAPVVIVNKGAVHLSYREILQADCDLDDFFTQLSRLV----------
>tr|F4P494|F4P494_BATDJ Putative uncharacterized protein (Fragment) OS=Batrachochytrium dendrobatidis (strain JAM81 / FGSC 10211) GN=BATDEDRAFT_12003 P
--------------------------------------DAQNIIVLTGAGCSVSCGIPDFRSKNGIYSEEDPQQMFDIKYFRIRPETFYSFAKEIYP--S
--NFKPSPSHMFIKLLED-KGKLLRNYTQNIDTLEKTAGIKNVVQCHGSFATATCIVCGHHVAGTDHIFAVPTCP-----GIMKPDIVFFGEKLEFNRIF
QEDRKKADLLIVMGSSLKVSPVADVKDLLPQHIP-QILINLEALPHMQHFDIQLLGYCDKIIVEICRNL----------
>tr|T1FYS5|T1FYS5_HELRO Uncharacterized protein OS=Helobdella robusta GN=HELRODRAFT_66888 PE=4 SV=1
--------------------------------------RSTKIIVLTGAGVSVSCGIPDFRSRNGIYAYPDPQAMFDITYFKKNPKPFFKFAKEIYP--G
--QFKPSLSHLFIGALER-SGKLLRNYTQNIDTLEPSAGITKIIQCHGSFSTASCMVCKHKVNAEQDVMDVPKCP-----SILKPDIVFFGESLEFHRQF
EMDKEECDLLIVMGSSLKVRPVAIIPNVLPSHVP-QILINRESLSHM-NFDVELLGDCDLIVQQL--------------
>tr|C3YKX2|C3YKX2_BRAFL Putative uncharacterized protein (Fragment) OS=Branchiostoma floridae GN=BRAFLDRAFT_175074 PE=4 SV=1
--------------------------------------GSKNIVVLTGAGVSVSCGIPDFRSRDGIYAFPDPQAMFDIDYFRKNPLPFFKFAKAIYP--G
--QYTPSRCHRFIRQLEE-QGKLLRNYTQNIDTLEQEAGIHRIIQCHGSFATASCTNCKRKVDCEQDIFNVPRCP-----AVMKPDIVFFGEGLKFHQTI
TVDKDKVDLLIVIGSRLKVRPVALIPSSIPAEVP-QVLINREPLNHM-TFDVELLGDSDVIVEEICRLL----------
>tr|A7SX90|A7SX90_NEMVE Predicted protein (Fragment) OS=Nematostella vectensis GN=v1g136467 PE=4 SV=1
--------------------------------------KCKNIIVLTGAGVSVSCGIPDFRSRDGIYAYPDPQAMFDITYFNQNPKPFFKFAKEIYP--G
--QFKPSLCHRFIHQLEE-HGHLLRNYSQNIDTLEQVAGITRVIQCHGSFSTASCMRCKHKVPCEEDIFRIPVCS--P--SIMKPDIVFFGESLNFYTHL
GDDSNKADLLIVIGSSLKVRPVALIPSHISPEVP-QILINREPLRHM-TFDVELLGDCDAIVSEL--------------
>tr|B7GE06|B7GE06_PHATC Predicted protein (Fragment) OS=Phaeodactylum tricornutum (strain CCAP 1055/1) GN=PHATRDRAFT_16859 PE=4 SV=1
--------------------------------------KIDNILVLSGAGVSVAAGIPDFRTPTGLYD-PYPEAVFDLNFYRRNPQPFVSLAKEIWP--G
I-SHLPTLTHSFLTLLAN-KGLLLRNYSQNIDGLEFLANLDKLVECHGHFRTASCVRCGKAADGEETIVE-PKCS--K--GFVKPDIVFFGEGLRFHSLL
EQDLERADCVLILGTSLQVAPVSMIPDMVEKSCK-RILFNRELVGSFDDRDVFHQGDCDDSIASLSKRL----------
>tr|F4R616|F4R616_MELLP Putative uncharacterized protein (Fragment) OS=Melampsora larici-populina (strain 98AG31 / pathotype 3-4-7) GN=MELLADRAFT_27327
--------------------------------------KIKKVVIMAGAGISTAAGIPDFRSPTGLYA-PYPEAIFDMDYFIDEPEAFYTLAKELCP--G
--KFKPTITHRFMKLLEI-KGILKRVLTQNVDTLERLAGVELIVEAHGSFAEAHCL-CRHKMSLEPLL-I-IWCK--K--SLVKPDIVFFGESLRFFS-H
LSDLPEADLLIVLGTSLQVQPFASLVTQVSSDCI-RLLINLERVGDQ-GRDILFLGPTDEGVKQLCGLL----------
>tr|F0YB49|F0YB49_AURAN Putative uncharacterized protein OS=Aureococcus anophagefferens GN=AURANDRAFT_27485 PE=4 SV=1
--------------------------------------EGAQCVVMLGAGASVAAGLPDFRTPTGLYDGPYPEAVFELDFFKENPAPFYKLARALWP--G
R-ESRPTLAHDFVRLLAD-RGQLIRCYTQNIDSLEREAGVDRVVAAHGNFDTATCVDTGLEVDVSAALFGMA---KHG--GLCKSDIVFFGEALRFFETL
KPDFDAAELLLVVGTSLEVHPFASLVDLGA--MP-RALINREKVGEMLPRDVFLQGDADDTVAALMDAA----------
>tr|B8C6L3|B8C6L3_THAPS Sir2-like transcriptional regulatory protein found in-like protein (Fragment) OS=Thalassiosira pseudonana GN=THAPSDRAFT_35956 P
--------------------------------------RYKKVLVVSGAGVSCSAGIPDFRTASGLYD-PYPEAIFDVDFYKSGPMPFVTLASEIWP--G
V-KYRPTLTHCFFNLLDK-KGTLSRIYTQNIDGLESVAGVNKMVECHGHFKSSSCIACKTPHDAESSMLK-PICN-----SLVKPDIVFFGEMMRFSERV
HYDVASADLIIVLGTSLLVAPVANIPDWVPSNVT-RLLINRDLVGTFSSTDVFMEGDCDESVRKLCEMI----------
>tr|A0A0P4WAB1|A0A0P4WAB1_9EUCA Uncharacterized protein OS=Scylla olivacea PE=4 SV=1
--------------------------------------QASNILVMVGAGMSTPSGIPDFRSPTGLYD-PYPEAIFDIHYFMMDPRPFFTLAQDLYP--G
V-NYKPNIAHHFLRLLHE-EGKLQMVYTQNIDGLERLAGIEKLVEAHGSFATASCTLCGRRHDSGKAI-E-PVMC--K--GKVKPDIVFFGENLVFWD-Y
HLQVPFTDLLLVMGTSLEVYPFAKIADEVGRKTP-RVLINLSAVGSFGDNDTVLGGDLVQTVEELTKAL----------
>tr|R7T8F1|R7T8F1_CAPTE Uncharacterized protein OS=Capitella teleta GN=CAPTEDRAFT_18508 PE=4 SV=1
--------------------------------------NQKKVVVMAGAGISTPSGIPDFRSPTGLYD-PYPEAIFDIRYFDQRPEPFYTLAKELHP--S
G-KYKPNTAHWFLRLLKD-KGHLLRIYTQNIDGLERMAGIEKLVEAHGGFYKATCRACLKKYTLEEKI-A-PRCN--D--GVIKPNIVFFGEQLRFWN-F
SVDMPQADLLIVMGTSLEVYPFASIADEVLPHTA-RLLFNMEPVGPFRHNDVISAGDLVTKVSEFCDLV----------
>tr|R1DAL5|R1DAL5_EMIHU NAD-dependent deacetylase SIRT2 (Fragment) OS=Emiliania huxleyi GN=EMIHUDRAFT_77385 PE=4 SV=1
--------------------------------------TPGSVVVMAGAGVSVSSGIPDFRSPTGLYD-PYPEAIFDLDFYRRNPKPFQRLCKELWP--G
--NFAPSPTHYFFKLLHD-KGKLRRVFTQNIDSLETASGLDLVVAAHGNFDGAHRVTPGAAVPLEQAA-H-A---AHG--GPVKPSIVFFGEQLRFFELA
RADFPKCELLLVLGTSLGVHPFAGLVGETRVGVP-RLLINRDRVGEHL-TDGWVGGDSDAAVRELASLL----------
>tr|A0A067R5P7|A0A067R5P7_ZOONE NAD-dependent deacetylase sirtuin-3, mitochondrial OS=Zootermopsis nevadensis GN=L798_06575 PE=4 SV=1
--------------------------------------RSSNVLVMAGAGLSTPSGIPDFRSPTGLYY-PYPEAIFDLVYFEKDPRPFLTLAKELYP--G
G-KYQPNLGHHFVHLLHK-KGKLLRMYTQNIDGLERLSGIEKLVEAHGGFSTSSCIRCSKKHDPYEAI-Q-VYCD--K--GLVKPDIVFFGEALRFWL-H
EMDTSLADFLIVIGTSLEVYPFSSVADAVQFNIP-RLLLNRTAVGSFGDNDAILSDDIIESVKNLAIAL----------
>tr|J9EW82|J9EW82_9SPIT SIR2 family histone deacetylase OS=Oxytricha trifallax GN=OXYTRI_08948 PE=4 SV=1
--------------------------------------KFKKIVVLTGSEISASAGIPDFRSPSGVYAKPFPEAIFSLDYFKINPDAFYTFFQSFDM--D
--SFKPTPTHYFLVLLDK-MGVLHMNFTQNIDALEEKAGMEKLLQVNGTVKGARCALCQRQMNQQEHIQKVYRCY--N--GPVKPNIVLFGEAMEFLIKY
Q-KIQDCDLLVVMGTALAVSQLNILFNSAPKDVP-KVLINMENTVEHGDKNLFLEGGCDKYIELIIKNC----------
>tr|B7FZ44|B7FZ44_PHATC Predicted protein (Fragment) OS=Phaeodactylum tricornutum (strain CCAP 1055/1) GN=PHATRDRAFT_12305 PE=4 SV=1
--------------------------------------KCQSIVVLAGAGMSVSAGIPDFRSADGLYAERDPTVALDQTLFLQNPLPMLELQREFILGTH
DRRWKATLAHRFVELLHAKTGKLVRLYTQNIDGLEDQCLLDKVIAVHGSMDRAECARCHTEADFDDCIKR-----CGY--AAMKPSIVLFKSSLIFFENL
PKDVESADILIIMGTSLRVAPANSLVWRVPRSSL-RLLVNREPAGNHLTRDYFAEGDCDDMLLELMEHL----------
>tr|R1D9K4|R1D9K4_EMIHU Uncharacterized protein OS=Emiliania huxleyi GN=EMIHUDRAFT_218522 PE=4 SV=1
--------------------------------------ECRSIAILTGAGVSVAAGIPDFRSPGGMYDRADPTAVVLKDMFFANAFPYLEVRRPFILGTR
ERRWRATLSHRFAELLHAKTGKLTRLYTQNIDGLDYQTALEKIVAVHGSIGKVACEGCGAPMEFDAEVRA-----CHR--PLVKPTTVLFGSSLEFFERS
AEDLPSVDLLLVAGTSLVVSPANSLVYRVPDSAV-RAVINAEPVGQELGRDLFLGGECDDTFLALMVQL----------
>tr|B7FYX0|B7FYX0_PHATC Silent information regulator protein Sir2 OS=Phaeodactylum tricornutum (strain CCAP 1055/1) GN=PHATRDRAFT_45850 PE=4 SV=1
--------------------------------------ECQSIAILSGAGVSVASGIPDFRSPGGMYDARDPTYVVSWEIFRHNPFPYLEVRRPFILGTQ
EQTWKATIAHRFAELLHIKTNKLTRVYTQNIDGLDRQCRIEKIVPVHGTMSRVACEGCGHPADYEENVRR-----CRQ--PLVKPTTVLFGRNLEFFQCT
EHDLPDLDLLIIAGTSLVVSPANSLVYKIPGDTI-RVVVNREPVGFDLARDFFARGACEDVFLELIKLL----------
>tr|A0A0L0G5Z3|A0A0L0G5Z3_9EUKA Uncharacterized protein OS=Sphaeroforma arctica JP610 GN=SARC_04132 PE=4 SV=1
--------------------------------------RIRNIMILSGAGVSTASGIPDFRSVGGMYDQIDPIHVVSLDLFRETQLPYLELRRPFILGLG
GNQWRPTLMHFLSDVLHK-KGLLTRVYTQNIDGLDFKTSVKKIIPVHGSLMVIKCESCKTEMDSAELTRT-----CGK--PYMKPDTVLYGSSLEFFMHW
ELDAQSSDLLIIAGTSLTVGPANRLPGLIRNSVP-RLVLNNEEVGMGLSTDTLLKGSCDSGCIALLQAL----------
>tr|Q1RL34|Q1RL34_CIOIN Uncharacterized protein (Fragment) OS=Ciona intestinalis GN=Ci-Sir2-e PE=2 SV=1
--------------------------------------KCKNIIVMCGAGISTAAGIPDFRTPTGLYD-PSPQAIFEINFFKENPQPFYTLAKELYP--G
--SFKPTTCHYFIKLLEQ-KGLLRRAYTQNIDTLERVAGVDKLVEAHGTFHTAHCV-CRMEYSQDEKV-K-PHCK--E--ELVKPDIVFFGEPLRFFNLR
YEDFRLCDLLIVMGTSLKVHPFASLVDGVEDTTP-RLLINREKCGE--YRDVCWLGDCDDGCLALADLL----------
>tr|A7RNW2|A7RNW2_NEMVE Predicted protein OS=Nematostella vectensis GN=v1g228435 PE=4 SV=1
--------------------------------------KCKHIIVMTGAGISTAAGIPDFRSPTGLYD-PYPESIFEIGYFRSNPEPFFALCKELYP--G
--SFKPTMSHYFIKLLYD-KKLLLRNYTQNVDTLERIAGVDLLVEAHGSFHTAHCI-CKKEYTKEDEI-A-PRCS--E--GVIKPDIVFFGESLRFHRLV
PQDMPHCDLIIIMGTSLAVQPFASLIDRVLATTP-RLLINKEKCGR--YRDVAWLGTTDDGCLALAELL----------
>tr|R7TK56|R7TK56_CAPTE Uncharacterized protein OS=Capitella teleta GN=CAPTEDRAFT_227953 PE=4 SV=1
--------------------------------------KCTNIITMAGAGISTSAGIPDFRTPTGLYD-PNPQAIFEIHFFRKNPAPFYALAKELYP---
G-VFKPTPCHYFLRLLHE-KKLLLRHYTQNIDTLERVAGIEMIVEAHGTFATAHCI-CRKQFSQEDKV-AIPKCT--G--GLVKPDIVFFGENLRFLSCS
MKDFPKCDLLIILGTSLAVQPFASLIDRVPDTTP-RLYINLEKSESDAYRDVFWQGTCDDGCVSLSERL----------
>tr|C3Z3T3|C3Z3T3_BRAFL Putative uncharacterized protein (Fragment) OS=Branchiostoma floridae GN=BRAFLDRAFT_146719 PE=4 SV=1
--------------------------------------KCKNIIVLTGAGISTSAGIPDFRSPTGLYD-PNPHAIFEIGFFKENPEPFFALAKELYP--G
--KFKPTWCHYFIKLLSD-KGLLLRNFTQNIDTLERVAGVGAMVEAHGTFYTAHCLGCRKEYTQEEKV-N-PRCP--D--GVVKPDIVFFGEAMKFFPSV
LADFPRCDLLIVMGTSLQVQPFASLVDRVPETCP-RLLINREKCGQ--YRDVAWLGDCDEGCKALAELL----------
>tr|A0A0D7A2J5|A0A0D7A2J5_9AGAR SIR2-domain-containing protein (Fragment) OS=Fistulina hepatica ATCC 64428 GN=FISHEDRAFT_50363 PE=4 SV=1
--------------------------------------KCRHVVLMV--SISTSAGIPDFRSPTGELH-PFPEAVFDLSYFRENPQPFYTLAHELYP--G
--KYNPTLTHAFIRVLDN-HNLLHRCFTQNIDTLERRAGVSKIVEAHGSFASQRCIGCRRPFDDERCV-N-PRCE--N--SLVKPDIVFFGESLEFARAA
-REVPLADLLIIIGTSLTVNPFAALANMPSELCP-RVLINLEQVGDLGPDDVLLLGKCDEVVHKLCREL----------
>tr|M2RM52|M2RM52_CERS8 Uncharacterized protein OS=Ceriporiopsis subvermispora (strain B) GN=CERSUDRAFT_112158 PE=4 SV=1
--------------------------------------QCKNIVVMLGAGVSTSAGIPDFRSPTGLYA-PYPEAVFEISFFRENPKPFYQLAHELMP--G
--RFRPTPTHSFVRLLST-HDWLHVCFTQNIDTLERRAGVELIVEAHGSFASQRCIECKTSFDDEEHI-E-PICK--E--GLVKPDIVFFGESLLFHQSI
-PKLRNADLLFVIGTSLTVQPFASLARMVPESCP-RVLVNLDHVGDFGPDDVILLGKCDEVVQDLCREL----------
>tr|A4VDQ9|A4VDQ9_TETTS SIR2 family transcriptional regulator OS=Tetrahymena thermophila (strain SB210) GN=TTHERM_00194149 PE=4 SV=1
--------------------------------------RFKKIIVLTGAGISTNAGIPDFRSKTGLYASSYPEQIFTIDYYQQNHKPFYEICREFVQ---
K-EYEPQQSHKFITELAK-QNLLYLNITQNIDGLELKAGLKYLIQAHGNLEKSHCIECHKEDTIEEGVLKCRKT-NCQ--GKLKPSVTFFGEKLYFYKIP
L-QMRFADLIIVMGTSLKVQPFASLLSYKSKSTP-LVVLNSENVVS--DCSLFIGGDIDKNLEEIMQEL----------
>tr|W4K836|W4K836_9HOMO Uncharacterized protein (Fragment) OS=Heterobasidion irregulare TC 32-1 GN=HETIRDRAFT_239283 PE=4 SV=1
--------------------------------------KCKNVFVMLGAGVSTSAGIPDFRSPTGMYG-PRPEAVFEMSFFRVKPQPFYTLAKELYP--G
--RYRPTLSHTFIKLLSQ-KNLLRMCFTQNIDTLERRAGIEKIIEAHGSFATQRCIECRRPFDDVKFI-K-PRCE--E--GLVKPDIVFFEESLAFTQAI
-PSLQEADLLIVMGTSLTVHPFASLANRVPPDCP-RVLINLDKVGNFGIDDVVLLGECDRIAKQLCVEL----------
>tr|F9XEI5|F9XEI5_ZYMTI Uncharacterized protein OS=Zymoseptoria tritici (strain CBS 115943 / IPO323) GN=MYCGRDRAFT_100618 PE=4 SV=1
--------------------------------------HCKKVVVMTGAGISTSAGIPDFRSPTGLYA-PYAEAVFDISYFREKPEPFYTLAHELYP--G
--KFRPTITHSFIKLLHD-KGLLLKHFTQNIDTLDREAGVDLIIEAHGSFARQSCIECKASYPDDEHI-A-PRCY--K--GLVKPEIVFFGEQLEFFAAR
-GLPAEADLCIVMGTSLTVQPFASLPGMCRDDTP-RVLINQERVGGLGSDDVLILGDCDDGVRKLAEAC----------
>tr|M2N9H8|M2N9H8_BAUCO Uncharacterized protein (Fragment) OS=Baudoinia compniacensis (strain UAMH 10762) GN=BAUCODRAFT_54779 PE=4 SV=1
--------------------------------------RCSKIVVMTGAGISTSAGIPDFRSPTGLYA-PYAEAVFDISFFRQNPEPFYALAHELYP--G
--KYRPTITHSFIRLLHD-KGLLLKLFTQNIDCLEREAGVDKIVEAHGSFARQSCIECKHPYPEERHI-A-PRCH--K--GLVKPEIVFFGEQLAFFRNR
-MLPAQADLCIVMGTSLTVQPFASLPQLAARSTP-RLLVNKERVGGLGSDDVVLLGDCDEGVRKLAKAC----------
>tr|C1FHA9|C1FHA9_MICSR Histone deacetylase, SIR2 family OS=Micromonas sp. (strain RCC299 / NOUM17) GN=MICPUN_86067 PE=4 SV=1
--------------------------------------KCKRIVVMAGAGISVSAGIPDFRTPTGLYD-PHPTAVFELDYFRENPKPFYLLAKELYP--G
--NFPPTPTHRFIRLLHE-KGLLTRCFTQNIDSLEAAAGIDKIVAAHGNFDAAHCLRA---ADVNAHV-R-MRCK--D--ELVKPDIVFFGEALRFNRLA
ATDFDDCDLLIVAGTSLAVHPFAGLVDFPSEDTP-RLLVNREVVGELDYRDALWLGDCDDGFMELATLC----------
>tr|U9UUE9|U9UUE9_RHIID Uncharacterized protein (Fragment) OS=Rhizophagus irregularis (strain DAOM 181602 / DAOM 197198 / MUCL 43194) GN=GLOINDRAFT_730
----------------------------------------KRIIVMAGAGISTAAGIPDFRTPTGLYD-PYPEAIFDMTYFKENPEPFFSLAKELFP--G
--NFMPTLTHYFLTLLYR-KNILLRCFTQNIDTLERLAGLEMIVEAHGSFAKSKCL-CKKFADAAEVV-K-PICT--V--GIVKPCITFFGEAMKFFL-R
LGDFQVCDLLIVIGTSLQVQPFASLVDSVGEKVP-RLLINLEKVGDI-MRDAFYKGTCDEGVRKLAELC----------
>tr|G6D8S6|G6D8S6_DANPL NAD-dependent deacetylase sirtuin 2-like protein OS=Danaus plexippus GN=KGM_03477 PE=4 SV=1
--------------------------------------RCQNVITLSGAGISTSAGIPDFRSPTGLYH-PEPQAIFEINFFRQNPKPFFTLAKELFP---
G-SFKPTISHYFIRLLHE-KGLLLRHYTQNIDTLERGAGIEKLVEAHGTFYTSHCI-CRKEYPLDGII-AIPICT--P--GVVKPDIVFFGESLRFQHCL
QEDFQKCDMLIIMGSSLEVQPFASLIDMVPEWCP-RLLINREKAGI--IRDVARLGECDDGCQELADRL----------
>tr|A2F9H1|A2F9H1_TRIVA Transcriptional regulator, Sir2 family protein OS=Trichomonas vaginalis GN=TVAG_413390 PE=4 SV=1
--------------------------------------KAKKIIFLTGAGISTAAGIPDFRSITGFYS-PEPSDVFNIKYFKENQEPFYDLCPSLLP--G
--KYKPTFIHYFGAYMAK-KGILLKQYTQNIDGLERIAGVDKLVESHGTFSTAHCTECKKEWKLEDKL-L-LHCT--K--GFIKPDIVFFGENLSFQHNA
RIDLRSCDMLLISGTSLKVNPFASLPGTAPEDVP-RVLINLDKVAQYTTRDVYLGGDCQETFKELARRL----------
>tr|C1BMY9|C1BMY9_CALRO NAD-dependent deacetylase sirtuin-2 OS=Caligus rogercresseyi GN=SIRT2 PE=2 SV=1
--------------------------------------TYKNIVILSGAGISTNAGIPDFRSPLGLYFKPYPEAVFEGSYFRKDPLPFYSLVREIYP--S
--RLEPTLTHKFLSLLSK-KKLLRRVFTQNIDGLEGLAGIEEIVEAHGSFARSYCTSCKREYELTREIFAVPKC-SCS--GIVRPDVVLFGESMRFSQLA
ESELKKADLLLVIGTSLAVAPFNGLVGLTQSGTP-RVYISKTRPGQSNDTDLVLLDDCDAVVLQICRQL----------
>tr|A0A0K2UXZ9|A0A0K2UXZ9_LEPSM Uncharacterized protein OS=Lepeophtheirus salmonis GN=Dsec\GM23107 PE=4 SV=1
--------------------------------------RYKNIVILCGAGISTNAGIPDFRSPFGLYFKPYPEAVFEGKYFNKDPNPFYGLIREIYP--S
--QLIPTDTHKFFTLLHQ-KGLLRRVITQNIDALEYLGGLDLVVEAHGSFRRSYCTKCSETYELPDAIFHVPKC-ACG--GVVRPDVVLFGETMRFCNLA
HNDLKNADLLLVFGTSLAVAPYNGLITLTKSQIP-RVYVSKTKPGQSTPNDLVLIEDCDQVVRNLCSKL----------
>tr|C1C037|C1C037_CALCM NAD-dependent deacetylase sirtuin-2 OS=Caligus clemensi GN=SIRT2 PE=2 SV=1
--------------------------------------SYKNIVVLCGAGISTNAGVPDFRSPLGLYFKPYPEAVFEGQTFRENPLPFYSLVREIYP--S
--RLEPTDTHRFLSLLHK-KGVLLRVFTQNIDALEYLGGLERVVEAHGSFRRSYCTKCKRTYELPNAIFTVPKC-SCG--GVVRPDVVLFGENLRFWECT
QSDLKKADLLFVIGTSLAVAPFNGLVNQVKSGTP-RVYLSKTKPGNSDPNDLVLLEDCDALVRTICDRI----------
>tr|A2GAR7|A2GAR7_TRIVA Transcriptional regulator, Sir2 family protein OS=Trichomonas vaginalis GN=TVAG_362260 PE=4 SV=1
--------------------------------------HATNTVFLTGAGTSVASGIPDFRTPIGLYAKPYPEAVFDIEFFDTNPGPFFDVCRNILP--G
--TFKPSPAHYLPVLFDK-HKLLTRLYTQNIDSLDISAGLDKIVEAHGSFTYLTCRKCGSKFEFAEEFQTVVHC-CKE--GVIKPDVVFYGEDLRFHHLS
ENDFSTANLLIIMGTSLTVSPCCMLPGYCPPNCV-RVLINNEPAGKCPTRDIFLKGDLQEICEKLINAL----------
>tr|H8WVK3|H8WVK3_CANO9 Uncharacterized protein OS=Candida orthopsilosis (strain 90-125) GN=CORT_0A00850 PE=4 SV=1
--------------------------------------TKKKVCLFTGAGVSTAAGIPDFRSPTGLYSKPYAEAVFDIDFFKEDPQPFYTLAEELFP--G
--KFAPTKFHYLVRILQE-KNLLQRVYTQNIDVLDRLAGVDFIVEAHGSFATSRCIDCKKEVSIEQMMK-TPTC---D--GFIKPDITFYGEGLKFFETW
EEDVDDVEVAVIAGTSLTVHPFASLPSSVDKSSL-RVLVNREKVGDLGKKDIVALLDCDEFAETLATLL----------
>tr|H3BDU0|H3BDU0_LATCH Uncharacterized protein OS=Latimeria chalumnae GN=LOC102364335 PE=4 SV=1
--------------------------------------RCKNIIIIAGAGISTASGIPDFRTPTGLYD-PCPEAIFDIDYFTYNPKPFFSLVKELYP---
G-NYQPNYIHYFVKMLHE-KGLLLKMYTQNIDGLERKAGIEKLVEAHGTFSTASCHSCCKPFPAKEAI-N-PRCK--S--GIVKPDIVFFGEDLRFYR-F
SKDFVNADLVFIMGTSLEIEPFASIVDSARSYVP-RLLLNRDLVGPFKNTDVAELGDLIENIKRLVGIL----------
>tr|C3Z1Z2|C3Z1Z2_BRAFL Putative uncharacterized protein (Fragment) OS=Branchiostoma floridae GN=BRAFLDRAFT_223028 PE=4 SV=1
--------------------------------------KCKNVVVMAGAGISTPSGIPDFRSPTGLYD-PYPEAIFDIDYFHMDSRPFYTLAKELYP---
G-NYRPNYVHYFIRLLHE-KGLLLRMYTQNIDGLERMSGISKLVEAHGTFATASCIRCNAKYSGKAAI-K-PKCT--K--GKIKPDIVFFGEDLRFYY-Y
LKDFPLCDLLLVMGTSLEVEPFASIVNSSRGYVP-RVLFNRDPVGPFGDTDCAELGDLVQGIQRFTRIL----------
>tr|H2L301|H2L301_ORYLA Uncharacterized protein OS=Oryzias latipes PE=4 SV=1
--------------------------------------QHKRVVVMAGAGISTPSGIPDFRSPSGLYD-PYAEAIFEIGFFHRNPAPFFALAKELYP--G
--NYRPNPTHFFVHLLHQ-KGQLLRMYTQNIDGLERVAGIEKLVEAHGTFATATCTSCLQKYKGE-AVMSVPKCSACG--GVVKPDIVFFGEELHFL-KY
LTDFPLADLLIIMGTSLEVEPFASLAGAVRSSVP-RLLINRDPVGPFVPQDVLQLGEVMGGVQALVEAL----------
>tr|I3KER5|I3KER5_ORENI Uncharacterized protein OS=Oreochromis niloticus GN=LOC100693812 PE=4 SV=1
--------------------------------------QFNRVVVMAGAGISTPSGIPDFRSPSGLYD-PYAEAIFEISFFHHNPNPFFALAKELYP--G
--NYRPNLTHHFVYLLHK-KGQLLRMYTQNIDGLERLAGIEMLVEAHGTFATATCTACLRKYEGK-DVMSVPKCPTCK--GVVKPDIVFFGEELHFF-KY
ITDFPLADLLIIMGTSLEVEPFASLAGAVRSSVP-RLLINRDLVGPFTPNDVVQLGDVVSGVQALVDAL----------
>tr|A0A096MAX3|A0A096MAX3_POEFO Uncharacterized protein OS=Poecilia formosa PE=4 SV=1
--------------------------------------RCKRVVVMAGAGISTPSGIPDFRSPSGLYD-PYAEAIFEIGFFHRNPNPFFALAKELYP--G
--NYQPNLTHYFVRLLHQ-KGQLLRMYTQNIDGLERVAGVEMLVEAHGTFATATCTSCLRKYDGE-EVMSVPRCPTCK--GVVKPDIVFFGEELSFF-KY
LTDFPLADLLIVMGTSLEVEPFASLAGAVRSSVP-RLLINRDLVGPFAPHDVTQLGDVVTGVKELVDAL----------
>tr|A2F8N6|A2F8N6_TRIVA Transcriptional regulator, Sir2 family protein OS=Trichomonas vaginalis GN=TVAG_480900 PE=4 SV=1
--------------------------------------NAKKILIFSGAGTSVASGIPDFRSPIGLYSKPRPESIFTRDYFKYHPEPFFSLIKFFLP--G
--KYKPSPAHFLAKLFEN-HGILLRHYSQNIDGLDKAAGLEHLVEWHGTLSKATCRKCSKKYTLDPKILAVPRC--CG--GVIQPDVMLYGDYNDLYTHL
DKDVEQADLLFVLGTSLKVEPFPSMIENVSYSIP-RVLINADPVCTYDTRDIFIPGDIQENVIKLIEKL----------
>tr|R4XIS0|R4XIS0_TAPDE Uncharacterized protein OS=Taphrina deformans (strain PYCC 5710 / ATCC 11124 / CBS 356.35 / IMI 108563 / JCM 9778 / NBRC 8474) 
--------------------------------------SAKNIIICAGAGISTSAGIPDFRSPTGLYH-DYPEQVFDIDFFRRRPEPFYQLAHELYP--G
--NFDPTVTHSFIRLLHN-KGLLLRCFTQNIDTLERRAGIERLVEAHGSFAGNHCISCGTVADADEVI-K-PRCK--K--ALVKPDIVFFGEGLVFFQRM
-NDFRHADLLIVMGTSLQVQPFASLPDRVKLDCP-RLLINLEEVGDFSTMDVVKLGSCDDTVKELADIC----------
>tr|F6WJA0|F6WJA0_HORSE Uncharacterized protein (Fragment) OS=Equus caballus GN=SIRT3 PE=4 SV=1
--------------------------------------ACQRVVVMVGAGISTPSGVPDFRSPSGLYS-PYPEAIFELEFFFHNPKPFFALAKELYP--G
--NYRPNVTHYFFRLLHE-KGLLLRLYTQNIDGLERASGISKLIEAHGSFASATCAVCRTPAPGE-DVMVIPRCPVCT--GIVKPDIVFFGEPLRFL-LH
VIDFPMADLLLILGTSLEVEPFASLSEAVQSSVP-RLLINRDLVGPLASRDVVQLGDVVHGVEKLVELL----------
>tr|H0XXD4|H0XXD4_OTOGA Uncharacterized protein OS=Otolemur garnettii GN=SIRT3 PE=4 SV=1
--------------------------------------ACQRVIVMVGAGISTPSGIPDFRSPSGLYS-PYPEAIFELTFFFHNPKPFFTLAKELYP--G
--NFRPNVTHYFLRLLHD-KGLLLRLYTQNIDGLERVSGISKLVEAHGTFATATCTVCQSPFRGE-DVMAVPRCQACT--GVVKPDIVFFGEPLRFL-LH
MVDFPMADLLLILGTSLEVEPFASLSEAVRSSVP-RLLINRDLVGPLASRDVAQLGDVVHSVERLVELL----------
>tr|H0W7K0|H0W7K0_CAVPO Uncharacterized protein OS=Cavia porcellus GN=SIRT3 PE=4 SV=1
--------------------------------------VCQRVVIMVGAGISTPSGIPDFRSPSGLYS-PYPEAIFELEFFFHNPKPFFTLAKQLYP--G
--NYRPNITHYFFRLLHD-KGLLLRLYTQNIDGLERVSGISKLVEAHGTFASATCTVCRRSFPEK-DVMMVPCCPVCA--GIVKPDIVFFGEPLRFL-LH
VLDFPMADLLLILGTSLEVEPFASLSEAVGASVP-RLLINRDLVGTFASRDVVQLGDVVHSVERLVELL----------
>tr|C6ZII8|C6ZII8_RABIT SIRT3 mitochondrial OS=Oryctolagus cuniculus GN=Sirt3 PE=2 SV=1
--------------------------------------ACQRVVVMAGAGISTPSGIPDFRTPSGLYS-PYPEAIFELAFFFHNPKPFFTLAKELYP--G
--NYRPNFTHYFLRLLHD-KRLLLRLYTQNIDGLERVAGISKLVEAHGTFASASCTVCRRCFPGE-DVMAVPRCPVCT--GVVKPDIVFFGEPLRFF-LH
VVDFPMADLLLILGTSLEVEPFASLSEAVRSSVP-RLLINWDLVGPLAGRDVAQLGDVVHGVGKLVELL----------
>tr|D8LVU5|D8LVU5_BLAHO Uncharacterized protein OS=Blastocystis hominis GN=GSBLH_T00000340001 PE=4 SV=1
--------------------------------------EVKNIVVMSGAGISVSAGIPDFRSPTGLYY-PTPESMFDIDFFREHPECFYSFVMDLFP--E
--QYLPTYTHYFIKLLNK-KGILLRNYTQNIDGLERQAEISRLVESHGTMATCSCI-CKKPQKTEKQI-S-PRCK--G--GLVKPDIVFFNEPLKFNWMS
TADMVTCDLLIVIGTSLTVQPFAGLVHKVKENVP-RMLINREPVGPFRFRDVVYLGDCDEGVKKLCDLI----------
>tr|D8LYJ7|D8LYJ7_BLAHO Uncharacterized protein OS=Blastocystis hominis GN=GSBLH_T00000949001 PE=4 SV=1
--------------------------------------RIKKICVLTGAGISCSAGIPDFRSPTGIYY-PNPEAMFELEFFKQNPAIFYKFLKKLLP--G
--KYKPTYVHHFLKLLEN-KGILLRVYSQNIDGLERLAGLTVLVEAHGSFATASCI-CGLEYPIKECI-N-PYCS--G--ALVKPDIVFYGENLKYTWMH
TADMVSCDMLLIMGTSLSVQPFCSLIHKVRENVP-RLLINNEAVGPFRLRDVYMQSDCDEGVKELARLL----------
>tr|A7RIU3|A7RIU3_NEMVE Predicted protein (Fragment) OS=Nematostella vectensis GN=v1g83259 PE=4 SV=1
--------------------------------------KCKNIVVLTGAGISTTAGIPDFRTPSGLFN-TTARSIFEIDYFQMNPKPFFVAAKAVYP--G
--QFKPTISHYFIKLLQN-KGLLLRHYTQNIDTLERVAGIDHLMEAHGSFHTGHCM-CNKEYSQDVEI-A-PRCT--D--GVVKPDIGFFGDPMKFYQLA
AEDFPKCDLLIVMGTSLIVQPFASLIARVSVDTP-RLLINREKCGY--KRDVAWLGTTDDGCLALAALL----------
>tr|G3W513|G3W513_SARHA Uncharacterized protein (Fragment) OS=Sarcophilus harrisii GN=SIRT3 PE=4 SV=1
--------------------------------------ACQRVVVMVGAGISTPSGIPDFRSPSGLYS-PYPEAIFELDFFFHNPKPFFALAKELYP--G
--NYRPNLAHYFLRLLHD-KGLLLRLYTQNIDGLERAAGITKLVEAHGTFASATCTICRQSFSGE-DVMAIPRCPICM--GVIKPDIIFFGEQLRFF-LH
MADFPMADLLIIIGTSLEVEPFASLSEASRRSVP-RVLINRELVGPFAHNDVAQLGDIIGGVERLVKAL----------
>tr|Q4S7H2|Q4S7H2_TETNG Chromosome 13 SCAF14715, whole genome shotgun sequence (Fragment) OS=Tetraodon nigroviridis GN=GSTENG00022785001 PE=4 SV=1
--------------------------------------RCRNVVVVAGAGISTASGIPDFRTPTGLYA-PYPEAVFSIDYFSDDPLPFFSLAKALYP---
G-HHRPNYIHYFVRMLHH-KGLLLRVYTQNIDGLERLCGIDKLVEAHGSFRTASCHLCYTSYPAAAAI-S-PVCS--A--ATVKPDVVFFGEDLKYFL-H
AEDFPKADLLIIMGTSLQIEPFASLVNTVRSTVP-RLLLNRHAVGPFQRGDHMELGDLEVTVRRLAQML----------
>tr|A4S2L7|A4S2L7_OSTLU Uncharacterized protein OS=Ostreococcus lucimarinus (strain CCE9901) GN=SRT3501 PE=4 SV=1
--------------------------------------GVKNVVVMTGAGISVSAGIPDFRSERGLYA-PYPQAIFELGYFREKPEAFYKLAKDLYP--G
--LYAPTPTHYFIKLLHD-RGLLRRCFTQNIDSLECATGLDKVVAAHGNFDSAKCLNDANIYEVE-AC-A-MTCA--G--EFVKPDIVFFGENLRFFECA
QKDFEVCDLLIVIGTSLVVHPFAGLIERPKEHVP-RLLINLERCGEAQYRDALFLGQCDDGVAELCSML----------
>tr|S9YNB2|S9YNB2_9CETA Sirtuin (Silent mating type information regulation 2) 3-like protein OS=Camelus ferus GN=CB1_000147006 PE=4 SV=1
--------------------------------------ACRRVVAMVGAGISTPSGIPDFRSPTGYYT-PYPEAIFELAFFFQDPKPFFTFAKELYP--G
--NYRPNATHYFLRLLHE-KGLLLRLYTQNIDGLERASGISKLVEAHGSFASATCTVCRRPIPEE-EVMAVPHCPVCT--GIVKPDIVFFGELLRFL-LH
VADFPMADLLLILGTSLEVEPFASLSEAVRSSVP-RLLINRDLVGSLASRDVVQLGDVVHGVKRLVELL----------
>tr|A0A098KX89|A0A098KX89_CRIGR NAD-dependent deacetylase sirtuin-3 OS=Cricetulus griseus GN=H671_3g10426 PE=4 SV=1
--------------------------------------ACRRVVVMVGAGISTPSGIPDFRSPSGLYS-PYPEAIFELGFFFHNPKPFFTLAKELYP--G
--HYRPNVTHYFLRLLHD-KELLLRLYTQNIDGLERASGISKLVEAHGSFASATCTVCRRSFPGE-DVMAVPCCPVCT--GVVKPDIVFFGEPLRFL-LH
VADFALADLLLILGTSLEVEPFASLSEAVQKSVP-RLLINRDLVGSFASTDVVQLGDVVQSVERLVDLL----------
>tr|L8HNR8|L8HNR8_9CETA NAD-dependent deacetylase sirtuin-3, mitochondrial OS=Bos mutus GN=M91_08503 PE=4 SV=1
--------------------------------------ACQKVVVMVGAGISTPSGIPDFRSPVGYYS-PYPEAIFELSFFFHDPKPFFTFAKKLYP--G
--NYRPNATHYFLRLLHE-KGLLLRLYTQNIDGLERASGISKLVEAHGSLASATCTVCRRPYPGE-DVMVVPRCPVCS--GVTKPDIVFFGEPLRFL-LH
LADFPMADLLLILGTSLEVEPFASLSDAVRSSVP-RLLINRDLVGSLAGRDVAQLGDVVHGVKRLVELL----------
>tr|B3RZX6|B3RZX6_TRIAD Putative uncharacterized protein OS=Trichoplax adhaerens GN=TRIADDRAFT_26603 PE=4 SV=1
--------------------------------------ECKNIIVMTGAGLSTAAGIPDFRSPIGLFTKTSPELVFSIDYFHENPSVFYEMSRGMTE--T
--DYKPTIAHYFLKLLAD-KNLLLRHYTQNVDGLDLAAGLDKVVTAHGTMYTAHCTTCHTKYTLEQQLLKVPRC-KCQ--GVIKPDVVLYGEQLKFFTMR
SADFPNCDLLIIMGTSLKVEPFASLVEHVPEHAP-RLLINLEETGQDHRKDIFWKGSCDDGCLKLADLL----------
>tr|A0A017S4M6|A0A017S4M6_9EURO Putative SIR2 family histone deacetylase OS=Aspergillus ruber CBS 135680 GN=EURHEDRAFT_416077 PE=4 SV=1
--------------------------------------PPPKIVALVGAGISTAANVPDFRSVTGLYAPPYPEAIFDINFFKHTPEPFYAIARARKP--R
--NLRPTLTHAFLALLAK-KNLLHFIFTQNIDGLEEDAGVSHILAAHGNWKSQRCYRCKKVYPDENAIETVPYCL--R--GVVKPDVVFFGQDLKFEEKE
KTKLPEADIMLVLGTSLKVAPCSRLPRSVREGVP-RVLVNLESAGDIGDGDVVALGQCDEVIRALNEEL----------
>tr|A0A064BDP2|A0A064BDP2_ASPOZ NAD-dependent histone deacetylase OS=Aspergillus oryzae 100-8 GN=AO1008_00749 PE=4 SV=1
--------------------------------------KATRIVVLAGAGISTAAGVPDFRSPTGLYDPPFPEAIFHINYFRHTPEPFYAIARARNP--K
--NLQPTISHAFLALLAK-KNLLDFVFTQNIDGLELDAGVEKVLSCHGNWKSQRCHKCKTPYPDGEAIETVPYCQ--G--GAVKPDVVFFGEPLAFEVEE
K-RVFGADLMIVMGTSLKVAPCARLPRQVKEGTP-RLLVNMVQVGDFGPSDVCILGSCDDGVRQLADSL----------
>tr|G4VR99|G4VR99_SCHMA Putative chromatin regulatory protein sir2 OS=Schistosoma mansoni GN=Smp_084140.1 PE=4 SV=1
--------------------------------------QVNKIITMVGAGVSTAAGIPDFRSPSGIYD-PTPNAIFTIDYFRRDPRPFFEIARRLYR---
P-EAKPTLAHCFIRLLHD-KDLLLRHYTQNVDSLERLSGLEKLVEAHGTFHTGHCI-CNKQHDFENEI-AVPQCL--R--NVVKPDVVLFGDSMKFFKNL
SSDLNNCDLLIIMGTSLTVLPFCAMIHRVGNDVP-RLYINREYNDGSTKRDIFWSGNADDGVVKISELL----------
>tr|C1LH16|C1LH16_SCHJA NAD-dependent deacetylase sirtuin-2 OS=Schistosoma japonicum PE=2 SV=1
--------------------------------------KINKIVTMVGAGISTAAGIPDFRSPSGVYD-PTPTTIFSIEYFQHDPRPFFEIARRLYR---
P-EAKPTLAHYFIKLLHD-KGLLLRHYTQNVDSLERLSGLEKLIEAHGTFYTGHCI-CNKQYDFDNDI-AVPRCP--Q--NVVKPDVVLFGESMKFFKNL
TSDLSNCDLLIIMGTSLTVLPFCAMIHRVGCDVP-RLYINREYNNGSSKRDVFWSGNTDDGVVKISELV----------
>tr|A2F8E1|A2F8E1_TRIVA Transcriptional regulator, Sir2 family protein OS=Trichomonas vaginalis GN=TVAG_409810 PE=4 SV=1
--------------------------------------NYKNVIVLTGAGISTAAGIPDFRSPIGIYARRDPTFVFDIDVFMDDPKPFWWIFSHLWPKDL
--WPRPTEMHYFIGYLNQ-LGVLKRVYTQNVDGLEIPGGLDKLVQCHGALPTCHCCDCHAAVPLARQIQPVPHC-CDG--EHVKPDVTFFGEAMRFEQTL
YEDFHSCDLCIITGTSLGVYPFADLVEEVPAGIP-RFVINYDKVKAKGGKDFFIGGDCQEAVKKIIAKA----------
>tr|V9IJE9|V9IJE9_APICE NAD-dependent deacetylase sirtuin-2 OS=Apis cerana GN=ACCB11329 PE=2 SV=1
--------------------------------------ENCKIITMAGAGISTSAGIPDFRSPSGLYH-PHPQAIFELDFFLENPEPFFMLARELLP--D
D-GFKPTPSHYFIRLLWE-KGLLLRHYTQNIDTLERVAGLEKLVEAHGTFHTGRCL-CRAPYTLPEQI-KIPKCE--E--GIVKPDIVFFGEMLRFHYLA
DRDFVQADLLIIMGSSLIVQPFASLVDRVRPNCP-RLLINKEKVGT--GRDVAWLGDCDIGCQLLADKL----------
>tr|T1IPY0|T1IPY0_STRMM Uncharacterized protein OS=Strigamia maritima PE=4 SV=1
--------------------------------------TCKNIIVLTGAGVSTSAGIPDFRSPSGLYD-PHPQAIFEISYFKENPQPFFSLAKELYP--G
--SFKPTPCHYFIRLLHE-KNMLLRLYTQNIDTLERIALIEKIVEAHGTFYTSHCMNCGKEYSLPEKI-A-PKCT--K--TVVKPDIVFFGENLRFYSCT
PKDFKKCDLLIVIGTSLTVQPFASLIEQVPTKTP-RLLINKEKAGQ--YRDVAWLGMCDDGCQALADAL----------
>tr|E0VSM4|E0VSM4_PEDHC NAD-dependent deacetylase sirtuin-2, putative OS=Pediculus humanus subsp. corporis GN=Phum_PHUM420680 PE=4 SV=1
--------------------------------------KCQKIVVMAGAGISTSAGIPDFRSPSGLYD-PHPQAIFAIDYFKENPEPFFHLAKELFP---
G-SYKPTVAHYFVRLLHE-KGLLLRHYTQNIDGLEKLAGIEKVVEAHGTFYTSHCL-CKKKYSLENKI-TVPLCE--K--GVVKPDIVFFGENLRFFSLS
EEDFPKADLLIIMGSSLAVQPFASLVDRVNSNCP-RLLLNREKAGQ--YRDVAFLGDCDELCEQLVDLL----------
>tr|T1EG16|T1EG16_HELRO Uncharacterized protein OS=Helobdella robusta GN=HELRODRAFT_114428 PE=4 SV=1
--------------------------------------RCKNIISMAGAGLSTSAGIPDFRSPSGLYD-PYPAAIFDLSYFKKNPEPFFVLAKNLLP---
T-ELIPTPCHHFLKLLHD-KGLLMRHYTQNIDTLERLAGLEVLVEAHGTFNSGHCL-CRSKYDFDNKI-SVPKCM--K--GVVKPDVVLFGENLKFFSLL
IQDFSKCDLLIVLGTSLNVQPFASLVHKVPKKSP-RLYVNLQKTSG--ERDVFWKGTCDDWCQLMAKKL----------
>tr|D6WU58|D6WU58_TRICA Putative uncharacterized protein OS=Tribolium castaneum GN=TcasGA2_TC009705 PE=4 SV=1
--------------------------------------NCKNIITMAGAGISTSAGIPDFRSPSGLYD-PHPQAIFELDFFHENPKPFFTLAKELYP---
G-SFKPTISHYFIKLLIE-KDVLLRHYTQNIDTLERIAGIEKIVEAHGTFYTGHCL-CRKEYQLEERI-KVPECE--K--GVVKPDIVFFGEALKFYSLI
ENDFKKCDLLIILGSSLVVQPFASLVDRVLDTCP-RLLINREKVNN--TRDVAWIGDCDEGCQLLADKL----------
>tr|F7H1P7|F7H1P7_MACMU Uncharacterized protein (Fragment) OS=Macaca mulatta GN=SIRT2 PE=4 SV=1
--------------------------------------RCRRVICLVGAGISTSAGIPDFRSPTGLYD-PYPEAIFEISYFKKHPEPFFALAKELYP--G
--QFKPPICLLITVL-KE-NSGRARWLTPNIDTLERIAGLEDLVEAHGTFYTSHCVSCRHEYPLSEKI-S-PKCE--Q--SLVKPDIVFFGESLRFFSCM
QSDFLKVDLLLVMGTSLQVQPFASLISKAPLSTP-RLLINKEKAGQ--YRDVAWLGDCDQGCLALAELL----------
>tr|Q298C7|Q298C7_DROPS Uncharacterized protein OS=Drosophila pseudoobscura pseudoobscura GN=Dpse\GA18650 PE=4 SV=1
--------------------------------------GFKKIITMVGAGISTSAGIPDFRSPSGLYD-PYPTAIFELGYFKKKPAPFFALAKELYP---
G-SFEPTTAHYFIRLLHE-KGLLLRHYTQNIDTLDRLAGIEKLIEAHGSFHTNHCI-CKKEYDMAKEI-SLPTCT--K--KIVKPDIVFFGENLKFHNSL
DGDFKECDLLIIMGTTLEVHPFASLAQLPGPRCV-RLLINRDAVGR--TRDVAFLGDCDEGVLELAKNL----------
>tr|B4K7T2|B4K7T2_DROMO Uncharacterized protein OS=Drosophila mojavensis GN=Dmoj\GI22229 PE=4 SV=2
--------------------------------------GFKKIITMVGAGISTSAGIPDFRSPYGLYS-PHPTAIFDVENFQRNPAPFFELAKELYP---
G-SFVPTPAHYFIRLLHE-KGVLQRHYTQNIDMLERLAGLEKLIEAIGSFNTNHCL-CKQLYDMAKKI-SLPICE--K--GLVKPDIVFIGENLKFYSSP
DEDFKECDLLIIMGTSLEMQPFASLIHRAGPRCI-RLLINRDAVGR--TRDVAFLGDCDAGVWALAEAL----------
>tr|A0A0B4LHF9|A0A0B4LHF9_DROME Sirt2, isoform B OS=Drosophila melanogaster GN=Sirt2 PE=1 SV=1
--------------------------------------GFRKIVTMVGAGISTSAGIPDFRSPSGLYS-PHPTAIFDLDYFEKNPAPFFALAKELYP---
G-SFIPTPAHYFIRLLND-KGLLQRHYTQNIDTLDRLTGLDKIIEAHGSFHTNHCI-CRKEYDMDAEI-ALPKCQ--Q--GVVKPDIVFFGENLRFYSSP
EEDFQDCDLLIIMGTSLEVQPFASLVWRPGPRCI-RLLINRDAVGQ--TRDVAFLGDCDAGVMALAKAL----------
>tr|S4PWH6|S4PWH6_9NEOP NAD-dependent deacetylase sirtuin 2-like protein (Fragment) OS=Pararge aegeria PE=4 SV=1
--------------------------------------RCQNVITLSGAGISTSAGIPDFRSPTGLYH-PEPQAIFEINFFRQNPKPFFTLAKELFP---
G-KFKPTVSHYFIRLLHE-KGILLRHYTQNIDTLERGAGIDKIVEAHGTFYTSHCL-CQKEYSLEERI-TIPICT--P--GVVKPDIVFFGESLRFQMCL
QADFQKCDMLIIMGSSLEVQPFASLIDMVPDWCP-RLLINREKAGL--GRDVAWLGDCDDGCLVVADKL----------
>tr|N6TN36|N6TN36_DENPD Uncharacterized protein (Fragment) OS=Dendroctonus ponderosae GN=YQE_04077 PE=4 SV=1
--------------------------------------GCKNVVTMAGAGISTSAGIPDFRSATGLYH-PCPEAIFHLSFFRKNPKPFFVLAKELFP---
G-AFKPTACHYFIRLLHE-NGLLLRHYTQNIDALERVAGIEKLVEAHGTCYTGHCL-CRKKYGLKERI-KIPICE--P--GIVKPDIVFFGENLKFYNSI
DVDFEKCDLLIILGSSLEVNPFASLIDMPSSLTP-RLLINREKAGH--TRDVAWLGDCNDGCQLLADRL----------
>tr|A0A067QQH3|A0A067QQH3_ZOONE NAD-dependent deacetylase sirtuin-2 OS=Zootermopsis nevadensis GN=L798_03932 PE=4 SV=1
--------------------------------------NCKNVITMAGAGISTSAGIPDFRSPSGLYH-PDPQAIFEIGFFQRNPQPFFTLAKELYP---
G-SFKPTTSHYFIRLLNE-KGLLRRHYTQNIDTLERVAGLEKIVEAHGTFHTSHCL-CKQEYEIEEQI-SVPTCE--N--GVVKPDIVFFGENLRFFSCN
EKDFSKCDLLIILGSSLAVQPFASLIDRVPKECP-RLLINREKAGQ--FRDVAWLGDCDEGCQMLSDKL----------
>tr|A0A0R3X1I6|A0A0R3X1I6_HYDTA Uncharacterized protein OS=Hydatigena taeniaeformis PE=4 SV=1
--------------------------------------KVRNIITAVGAGISTSAGIPDFRSPTGIYD-PSPMSVFELSYFERNPKPFFEVARRLYR---
P-YAKPTTAHYFIRLLCD-KGLLLRHYTQNVDQLERISGLDKMVEAHGSFHTGHCL-CHKEYPFEGKI-DVPKCT--D--GVVKPDVVFFGEGLKFTRGV
KRDFPKCDLLIIMGTSLQVLPFSGIVNCTKSGVP-RLYINREYTDGS-KTDVFVKGDADDTCLRFAELL----------
>tr|A0A068XGY1|A0A068XGY1_HYMMI Chromatin regulatory protein sir2 OS=Hymenolepis microstoma GN=HmN_000916700 PE=4 SV=1
--------------------------------------KVCNIITAVGAGISTSAGIPDFRSPTGIYD-PSPMAVFDISYFERNPKPFFEVARRLYR---
P-FAKPTTAHYFIRLLAE-KGLLLRHYTQNVDQLERISGLDKMVEAHGSFHTGHCL-CRKEYPFEARI-DVPRCL--G--GVVKPDVVLFGEGLKFTHGV
QKDFPKCDLLIIIGTSLQVLPFCGIVNCTRKGVP-RLYLNREYTSGS-KTDVFVKGDADELCLRFAELL----------
>tr|A0A074ZEQ5|A0A074ZEQ5_9TREM Uncharacterized protein OS=Opisthorchis viverrini GN=T265_14142 PE=4 SV=1
--------------------------------------KAKNIITLAGAGISTAAGIPDFRSSSGIYD-PHPMAVFSLDYFKTNPKPFFEVARRLYR---
P-HAKPTLTHYFVRLLHE-KTLLRRHYTQNVDDLERLSGLDKFVEAHGTFHTGHCQ-CHEEYTFEDQI-RVPKCS--N--GVVKPDVVLFGENLKFYDGF
LQDFSACDLLLIMGTSLQVLPFAGLIHRVGPRVP-RLYLNREYSEDD-TRDVFVRGDTDSSVLKLAELL----------
>tr|G1LQG6|G1LQG6_AILME Uncharacterized protein OS=Ailuropoda melanoleuca GN=SIRT2 PE=4 SV=1
--------------------------------------RCRRVICLVGAGISTSAGIPDFRSPTGLYA-PYPEAIFEIGYFKKHPEPFFALAKELYP--G
--QFKPTVCHYFIRLLKE-KGLLLRCYTQNIDTLERVAGLEDLVEAHGTFHTSHCTSCRREYTLSEKI-S-PKCE--H--SVVKPDIVFFGENLRFFSCM
QSDFLKVDLLIIMGTSLQVQPFASLISKAPLSTP-RLLINKEKTGQKLYRDVAWLGDCDQGCLALADLL----------
>tr|A0A0P5MP46|A0A0P5MP46_9CRUS NAD-dependent protein deacetylase sirtuin-2 OS=Daphnia magna PE=4 SV=1
--------------------------------------NVRNIITMAGAGISTSAGIPDFRSPSGLYSGPYPEAIFEIEYFRKHPEPFFAMAKELYP---
K-TFEPTPCHYFLRLLNK-KGLLLRHYTQNVDALERVAGIEKLVEAHGTLHTSRCINCREEYDRKEKVLAVPRCEQCK--AVVKPDAVFFGEPLRF-RLV
EEDFPNCDLLIILGTSLVVQPFSSLVDRVPPRCP-RLLINHEEAGNEDFRDVAWLGDCDEGCYLFAEKL----------
>tr|A0A0L0HPN6|A0A0L0HPN6_SPIPN Uncharacterized protein OS=Spizellomyces punctatus DAOM BR117 GN=SPPG_02089 PE=4 SV=1
--------------------------------------GVKRILVLTGAGISTSAGIPDFRSPTGLYD-PYPEAIFDISYFRRKPEPFFTLARELYP--G
--SFRPTLSHYFIRLLQE-KGVLLRNFTQNIDTLERVAGIDSLVEAHGSFATAHCRGCGKEYTQETKI-A-PTCE--S--GLIKPDIVFFGESLRFHRLI
AADFHKCDLAIIIGTSLQVAPFSHLINMVPPQIP-RLLINREIVAVE-RRDAVFLGTCDEGCEKLAELL----------
>tr|E4YK70|E4YK70_OIKDI Uncharacterized protein OS=Oikopleura dioica GN=GSOID_T00028352001 PE=4 SV=1
--------------------------------------KVKNIVMVVGAGISTSAGIPDFRTPTGLYS-PYPEAVFDIKYFKKKPQAFYTLSKELLP--G
--FYAPTITHHFIARLGK-LGLLKRIYTQNIDGLERLAGLNRLVEAHGSFASSKCT-CKKAYPNTPKL-A-MECQDDV--AYVKPDIVFFGEGLRFHDLY
HKDLKECDLMIVMGTSLYVYPVAGIPDDVHRSCP-RILINRELVGSFRTADAFYCGNADDGSLRLAKAL----------
>tr|A8PS73|A8PS73_MALGO Uncharacterized protein OS=Malassezia globosa (strain ATCC MYA-4612 / CBS 7966) GN=MGL_0206 PE=4 SV=1
---------------------------------------------MAGAGISTSAGIPDFRSPTGLYSKPYPEALFDIQYFRRDPQPFYTLFEELYP--D
GTKYRPTLTHTFIRLLEK-KGKLLRLFTQNIDTLEHLSGLDKIVEAHGSFSKARCINCKTPVSREKKVKGVARCETLA--PPIKPDITFFGESLRFFERL
Y-DLRRANLLLVMGTSLVVQPFASLIDEVPLDCP-RALLNLERVGETGSRDIFCPGAVDKTVRLIAQKC----------
>tr|A0C2R2|A0C2R2_PARTE Uncharacterized protein OS=Paramecium tetraurelia GN=GSPATT00034557001 PE=4 SV=1
--------------------------------------EFKKITIAAGAGISVAAGLSDYRSKTGLYDKSNPEQVYDINVFRKNPSLYYSVSKEFGT--H
NLDLQPTFAHQFIYHLDR-NDQLLNCFTQNIDGLELVAGVSKVIQVHGHRRTASCIDCKKTYCVKQNVDKIMKC-DCN--GLIKPDVVFFGQSLLYFEKL
P-EISLSDLVIIMGTSLQVQPFSNMIYRINENVP-IVLINKETNLRRLNNKLLIKGDVQDIISSIMKQL----------
>tr|E5SBK0|E5SBK0_TRISP NAD-dependent deacetylase Hst2 OS=Trichinella spiralis GN=Tsp_01124 PE=4 SV=1
--------------------------------------LVKRIVVLVGAGISVPSGIPDFRSPSGFYRESDPASVFDLKLFKRDPTLFYKVAWRLFP--G
--IHKPNEVHYFIRLLQE-KDLLLRVYTQNIDD----AGINMIVEAHGSFRCGKCTQCSKKVSFIDVVRRVPLC-RCR--GVIKPDVVFFGEVLRFMK-Y
VNDIPSADLLIVMGTSLEVYPFAGIIDLVKHTTP-RLLINKIAVGQFSQNDYIYEGDVVKGILELCKLL----------
>tr|G3U401|G3U401_LOXAF Uncharacterized protein OS=Loxodonta africana GN=SIRT3 PE=4 SV=1
---------------------------------------------MVGAGISTPSGIPDFRSPRGLYS-PYPEAIFELSFFFRNPKPFFTLAKELYP--G
--NFRPNVTHYFLRLLHD-KGLLLRLYTQNIDGLERASGISKLVEAHGTFASATCTICLRSCPGE-DVLAVPSCRVCT--GIVKPDIVFFGEPLRFL-LH
VADFPMADLLVILGTSLEVEPFASLSEGVCSSVP-RVLINQDVVGTFAGRDVVQLGDVVHSVEKLVKLL----------
>tr|B0S7D4|B0S7D4_DANRE Uncharacterized protein OS=Danio rerio GN=sirt3 PE=4 SV=1
---------------------------------------------MAGAGISTPSGIPDFRSPSGLYD-PYAEAIFEINYFHHNPNPFFALAKELYP--G
--NYQPNLTHYFIRMLHD-KEQLLRMYTQNIDGLERMAGIKMLVEAHGTFATATCTVCRRDYKGE-DIMAVPKCPTCK--GIIKPDIVFFGEELHFF-TY
LTDFPIADLLIVMGTSLEVEPFASLAGAVRGSVP-RLLINRDLVGPFAHTDVAELGDVVNGVKKLVELL----------
>tr|B3RLQ6|B3RLQ6_TRIAD Putative uncharacterized protein OS=Trichoplax adhaerens GN=TRIADDRAFT_19190 PE=4 SV=1
--------------------------------------SIEKIIVLTGAGVSTASGLPDFRSPSGLYD-SDPMDIFDISFFDLNPHPFYRVAKHLHA---
S-NYKPNYCHYFLKLLLE-KNLLLRIYTQNIDGLERKAGIEKLIEAHGSFANATCRICKKRYTSSGAI-Q-PRCK--Q--GVIKPDVVFFGENLRFFTEQ
ATDFKLCDLLIVMGTSLQVYPFASLANQVSSSVP-RILINNEIVGTFGNKDVMEVGDIIKGLKKLTQSL----------
>tr|A0A093BJX5|A0A093BJX5_CHAPE Uncharacterized protein (Fragment) OS=Chaetura pelagica GN=M959_12006 PE=4 SV=1
--------------------------------------ECRRVVVMAGAGISTPSGIPDFRSPSGLYS-PYPEAIFELTYFFINPKPFFTLAKELYP--G
--NYRPNYAHYFLRLLHD-KGLLLRLYTQNIDGLERVAGIDKLVEAHGTFATATCTVCRRNFPGE-DVLAVPRCPVCT--GVVKPDIVFFGEELRFL-LH
LTDFPRADLLFVIGTSLEVEPCASLAGAVRGSVP-RVLLNRDLVGPFAHRDVAQLGDVVSGVEKLVELL----------
>tr|F6RAU2|F6RAU2_XENTR Uncharacterized protein (Fragment) OS=Xenopus tropicalis GN=sirt3 PE=4 SV=1
--------------------------------------LYRRILVMVGAGISTDSGIPDFRSPSGLYS-PYPEAIFDLRYFLREPQPFLHLARDLLP---
G-HHHPNTAHHFLRLLSD-KEVLLRLYTQNIDGLERAAGIEKLVEAHGSFSSATCTMCLKSYPGEKAV-E-PLCS--G--GLIKADIVFFGEQLRFLL-H
LTDFPRADLLFVIGTSLEVEPFASLVYAVRASTP-RVLINRDSVGPFVGLNVLELGEVTAGIKQFVQFL----------
>tr|H2ZB26|H2ZB26_CIOSA Uncharacterized protein OS=Ciona savignyi PE=4 SV=1
--------------------------------------GVKNIIVMAGAGISTASGIPDFRSPTGLYD-PYPTAVFDLDYFHSNPKPFFELAKELYP--S
G-KYRPNAVHYFVRCLHE-RGLLLRMYTQNIDGLERLAGIMKLVEAHGTFTSASCTKCGKKYNGEDKI-K-PRCQ--Y--GIIKPDIVFFGEDLRFYY-Y
LKDFPACDLLLVMGTSLQVEPFASLVDSTRATTP-RLLLNMVKVGPFTRTDLSITGDISDSIHKLADAL----------
>tr|V4AXY6|V4AXY6_LOTGI Uncharacterized protein (Fragment) OS=Lottia gigantea GN=LOTGIDRAFT_63645 PE=4 SV=1
--------------------------------------QVKNVVVVAGAGISTPSGIPDFRTPTGLYD-PYPEAIFDIDYFHRNPKPFFTLAKELFP--S
LGNYRPNYIHYFVRILHE-KGMLLRMYTQNIDGLERLAGISKLVEAHGTFATATCILCGHKCDGDDRI-D-PKCK--P--GMVKPDIVFFGEDLKFYY-H
LKDMLQADIILIMGTSLEVQPFAGIIDSVRWQVP-RILFNRDIVGPFRSKDVVAEGDILETMQKFVDMI----------
>tr|E1ZEI0|E1ZEI0_CHLVA Putative uncharacterized protein OS=Chlorella variabilis GN=CHLNCDRAFT_31016 PE=4 SV=1
---------------------------------------------MCGAGISRSCRIPDFRSPTGLYS-PYPHAVFELGYFRSNPRPFFLLAKELFP--G
--NYLPTPTHFFMKLLHD-KGLLLRCFTQNIDSLEHQAGLEAVVAAHGNFDSARCI-CRRPHDTQQAV-APCYCS--G--GLVKPDIVFFGESLRFWERV
PLDFSAADLLIVLGTSLVVHPFAGLIDHVGPQVP-RLLVNREVAGEAAYRDALYLGDCDAGVRQLCQLL----------
>tr|D3L5Q4|D3L5Q4_9BACT Transcriptional regulator, Sir2 family OS=Anaerobaculum hydrogeniformans ATCC BAA-1850 GN=HMPREF1705_02238 PE=4 SV=1
--------------------------------------KAQKICLLSGAGISTNAGIPDFRGPKGLYR-DNPERIFDISYFYRDPSLFYKFHKEFLK--A
LQQIKPTFSHYFFAKLEE-KGKLIGIITQNIDSLHQRAGAKKVYEIHGGVWESYCLKCGKKFNYEKKTMETPHC-SCG--GVIKPDIVFFGEPV-YLDKC
IELARESDLFFVVGSSLVVTPAALIPAEC---KGTIVIVNKGDFSTTYRVDLVADEDIDAFFKSIDEHL----------
>tr|I0GKX2|I0GKX2_CALEA NAD-dependent deacetylase OS=Caldisericum exile (strain DSM 21853 / NBRC 104410 / AZM16c01) GN=npdA PE=4 SV=1
--------------------------------------NAKSISVLTGAGISVNAGIPDFRGETGIYT---SENVFDIDYFFENPKPFYDFVRVMYP--V
FEKAKPTLAHKFLADLDH-NHS-VCIVTQNIDLLHEKAGSKNVIHLHGSVERSHCLKCGKEYSFEELVIKVPYC-SCG--GLIKPDIVFFSEPV-DFDKA
IECVSASDIFFALGTSLEVYPANSLVQFA---RGNKILINKKETEMDY-FDIVVHEDLDNFFKELQSKG----------
>tr|I4BYJ9|I4BYJ9_ANAMD NAD-dependent protein deacetylase, SIR2 family OS=Anaerobaculum mobile (strain ATCC BAA-54 / DSM 13181 / NGA) GN=Anamo_1767 PE=
--------------------------------------EAKKICLLSGAGISTNAGIPDFRGPKGLYR-ENPERIFDISYFYRDPSLFYRFHREFLR--A
LQQVQPTFAHKFFAKLEE-IGKLIGIITQNIDSLHQRAGSKKVYEIHGGVWESFCIKCGKAYTYEKKTFEIPRC-ACG--GVIKPDIVFFGEPV-YLDKC
IQLARESDLFFVVGSSLVVTPAALIPAEC---RGTIVVVNKGEFSTAYKVSLVVDEDIDAFFRSVNEHL----------
>tr|H0UP47|H0UP47_9BACT NAD-dependent protein deacetylase, SIR2 family OS=Thermanaerovibrio velox DSM 12556 GN=TheveDRAFT_1432 PE=4 SV=1
--------------------------------------GARRIGVLTGAGISTGAGIPDFRGPKGIYR-ENPEAIFDIRRFNEDPSEFYRFHRGLME--M
MLKAEPTFTHRFLAGLEG-SKK-VTVITQNVDGLHQRAGSKDVIEIHGGITHNFCSSCGKSYSIEQLMDLVPRC--CS--GTIRPDIVFFGEPV-QLERC
FSAASESDLMMVIGSSLNVTPAALIPSSS---KGVLAVVNLGEVNTFNRVDIMAEDDIDRFFKRVSENL----------
>tr|A0A0C7P537|A0A0C7P537_9BACT NAD-dependent deacetylase OS=Defluviitoga tunisiensis GN=sir2 PE=4 SV=1
--------------------------------------RSKNIAVLSGAGMSTNSGIPDFRGPNGIYT-QNPESIFDIDYFYEDPSLFYKFHKTFLE--M
IQQAEPTFTHKFLVQIEE-ENKLSGIITQNIDSLHQKAGSKKVYEIHGGCWDNYCLKCGKHYTQAKKMQQIPKC-KCG--GIIKPDIVFFGEPV-YLGVS
EKIMTRSDLVLVLGSSLTVMPAAFLPSLT---KGKIVVVTKGTVSTSYKGAFIVNEDLDTFFIEVAEEY----------
>tr|D1Y2P7|D1Y2P7_9BACT Transcriptional regulator, Sir2 family OS=Pyramidobacter piscolens W5455 GN=HMPREF7215_2524 PE=4 SV=1
--------------------------------------SSRSTAVVSGAGLSTAAGIPDFRGPQGIYR--EADKLFDINYFERDPSYYYRFHRECER--M
LARIEPTFTHKFLARLEA-EGRLSGIVTQNFDGLHEAAGSKTIYQIHGTIRHAHCTKCGEYYGYDKMLETVPIC--CG--GVIKPDIVFFGESV-FLTEC
ERLCSRAKLLFVLGSSLNVVPAAFLPQLC---RGKIVVVNRGEVSADYRITLRVDADLDAFFRALEAEL----------
>tr|D2Z8A5|D2Z8A5_9BACT Silent information regulator protein Sir2 OS=Dethiosulfovibrio peptidovorans DSM 11002 GN=Dpep_1678 PE=4 SV=1
--------------------------------------EAESIAVLSGAGVSTSSGIPDFRGPNGIYR-IEPERIFDIDFFSRDPAFFFKFHREFLK--A
LKEVSPSYTHRFLTALER-EGSLKGIVTQNIDALHHKAGSKNVLEIHGGVWKSTCLSCGKSYDYEKKTMEIPHC-KCG--GVIKPDIVFFGEDV-HLEES
RSIISQADLLLVLGSSLTVVPAALLPSCC---NGKIVVVNKGDVSGAYRIDLRIDGDLDEFFGDLNEEL----------
>tr|A9BHU8|A9BHU8_PETMO Silent information regulator protein Sir2 OS=Petrotoga mobilis (strain DSM 10674 / SJ95) GN=Pmob_1359 PE=4 SV=1
--------------------------------------NSNSIAVLSGAGMSTNAGIPDFRGPNGIYT-ENPERIFDLDYFYLDPSLFYKFHKKFLE--Y
ITKAEPTFTHKFLVQLEK-EGKLKGIVTQNIDSLHQKAGSKKVYEIHGGCWKNYCTKCKRKYSQEEKMNNVPKC-NCG--GVIKPDIVFFGEPV-YLTES
EILMKNSELVLVLGSSLAVIPAAMLPSLT---KGKIIVVNKGEISEMYKVALIVNEELDTFFMQVAKEW----------
>tr|G7V9H2|G7V9H2_THELD Silent information regulator protein Sir2 OS=Thermovirga lienii (strain ATCC BAA-1197 / DSM 17291 / Cas60314) GN=Tlie_0789 PE=4
--------------------------------------KANNIVLLSGAGMSTNAGIPDFRGPNGIYR-VNPERIFDIDYFLEDPSFFYKFHREFLQ--T
LKNIKPTYAHKFFAALEK-NGKLKGIITQNIDSLHQMAGSKNVMEIHGGIWKSFCIDCNKTWDYEKLVFSVPRC-RCG--GIIKPDIVFFGEMV-HLEES
QKLVKECDLLFVVGSSLVVTPAALLPRLA---RGKIIIVNKGETNKSYIPTLHVEQDIDEFFKAVNYHI----------
>tr|D5EDA6|D5EDA6_AMICL Silent information regulator protein Sir2 OS=Aminobacterium colombiense (strain DSM 12261 / ALA-1) GN=Amico_0395 PE=4 SV=1
--------------------------------------SSRKVVLLSGAGMSTNAGIPDFRGPNGIYR-TDPELIFDIDYFYQNPSFFYEFHREFLK--T
INEIQPTFSHYFFSNMEK-GGLLKGIITQNIDALHQKAGSEKVFEIHGSMWQSFCTRCGQEYDYKHKVLKVPLC-ICK--GVIKPDVVFFGENV-YLNEC
QTLIKNADILFVVGSSLTVTPAAYLPSMC---SGKIVVINKGEISHDYRIFIHGKYDIDEFFNALEVEL----------
>tr|A7HL19|A7HL19_FERNB Silent information regulator protein Sir2 OS=Fervidobacterium nodosum (strain ATCC 35602 / DSM 5306 / Rt17-B1) GN=Fnod_0747 PE=
--------------------------------------NSKFTTVLTGAGVSVPSGIPDFRSKNGVYS-WGQ-EIFDIDLFHQNPDRFYEFAKQELI--K
MLDVEPNEIHYLLAYLEK-LNIVKGVITQNIDNLHKKAGSQKVAEIHGNVRTWSCLKCGKRYDLFHKEFI-NFR-ECG--GVTKPDIVFFGEMLNEYSKA
ENWAKESDVFIAMGTSLVVYPAAQLPIYAKHSGAKLCIINKNETVLDD-ADLVIHIDLIDFAKEVRRHF----------
>tr|A8F8U9|A8F8U9_PSELT NAD-dependent protein deacetylase OS=Pseudothermotoga lettingae (strain ATCC BAA-301 / DSM 14385 / NBRC 107922 / TMO) GN=cobB P
--------------------------------------SCRYGVALTGAGISTPSGIPDFRSPTGLYS-YPE-NVFDIDYLYNNPEGFYRFCKEALI--P
MADAKPNVAHYLLAKLEQ-KGYIKAVITQNIDGLHQKAGNQNIIELHGSIYNYYCIKCLKRYTIDNMLSKVPKC-SCS--GMIRPDIVFFGEQLKALSEA
EYHSINCDLMIVFGSSLLVYPAAQFPYIAKMNGSKLIIVNSGRTGLDH-CDLKIEKELSTFAN-E--FF----------
>tr|G4FDY0|G4FDY0_THEMA NAD-dependent protein deacetylase of SIR2 family OS=Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) GN=Tm
--------------------------------------ESRLTVTLTGAGISTPSGIPDFRGPNGIYK-YSQ-NVFDIDFFYSHPEEFYRFAKEGIF--P
MLQAKPNLAHVLLAKLEE-KGLIEAVITQNIDRLHQRAGSKKVIELHGNVEEYYCVRCEKKYTVEKKLESVPLC-DCN--SLIRPNIVFFGENLDALREA
IGLSSRASLMIVLGSSLVVYPAAELPLITVRSGGKLVIVNLGETPFDD-ATLKYNMDVVEFAR-R--VM----------
>tr|Q0AY57|Q0AY57_SYNWW Regulatory protein, sir2 family OS=Syntrophomonas wolfei subsp. wolfei (strain DSM 2245B / Goettingen) GN=Swol_1033 PE=4 SV=1
--------------------------------------RSHNTVVVTGAGISTEAGIPDFRGPEGIYR-NRVMKIINIDFFRNNPLEFYKFYRQY-F--I
FPPVEPGKAHQVLAEMEK-AGIIKAIVTQNIDNLHQKAGSQKVIPIHGNGARFLCQERNCRSVHDVNTYPIPRC-QCG--GILKPDVVLFGEHI-NYPDA
MDRILGARVLVVIGSSLTVYPLAGFVKEFSTFTQYLIIINKGPTPLDH-AVVKLQE--GNTGELLEEIF----------
>tr|D7CKP6|D7CKP6_SYNLT Silent information regulator protein Sir2 OS=Syntrophothermus lipocalidus (strain DSM 12680 / TGB-C1) GN=Slip_0497 PE=4 SV=1
--------------------------------------KSKNTVVVTGAGISTEAGIPDFRGEKGIYR-QRVMNIINIDAFKRNPEAFYEFYRKH-F--M
FPPVEPSKAHFMLAELEK-RGFVKGIVTQNIDNLHQRAGSRNVIPIHGNGDRFICTRHGCGHVHPIEAYPVPLC-KCG--GILKPDVVLFGEHI-HYFDA
RDLILRAKLLVVIGSSLTVYPLAGFVKEFSTFYQDLVIINKGRTELDH-ALVKVDT--DNTGAVLEEIN----------
>tr|K4LFC9|K4LFC9_THEPS NAD-dependent histone deacetylase silent information regulator Sir2 OS=Thermacetogenium phaeum (strain ATCC BAA-254 / DSM 12270
--------------------------------------SSRNTVVVTGAGISTEAGIPDFRGEKGIYR-QKVTALLNINAFRKRPREFYEFYRRY-F--L
LPEVKPSRAHLLLADLEK-KGIIKAVVTQNIDNLHQMAGSKRVIPVHGRADRFLCTGIGCRFESDVRDYPVPKC-ECG--NILRPDVVLFGEPI-NHRLA
RDTILAAQVLLVIGSSLTVYPLAGFVSEYCTGDRTMIIINKGPTALDY-ATLKLDV--ESTAEVLEKIA----------
>tr|A0A0E3W3I4|A0A0E3W3I4_9FIRM Sirtuin family OS=Syntrophomonas zehnderi OL-4 GN=2019 PE=4 SV=1
--------------------------------------NSNYTVVVSGAGISTEAGIPDFRGQNGIYR-DQVMRIINIDFFNRYPEEFYQNYRQY-F--N
FPQVEPSPAHMALADLEK-KGYIKGIVTQNIDNLHQLAGSRNVIPIHGNAQEFICTAYHCRRIYDYANSRVPKC-ICG--AVVKPNVVLFGENI-NYMGA
REMILDARLLIVIGSSLTVYPLAGFVSEYCNTSRDLVIINKGPTQLDY-ARVKIDPGTGSTGEVLAEIC----------
>tr|K4M9N5|K4M9N5_9EURY Silent information regulator protein Sir2 OS=Methanolobus psychrophilus R15 GN=Mpsy_0074 PE=4 SV=1
--------------------------------------RSKHCVFLSGAGISTFSGIPDFRGKDGIYR-FDADKIFDIDYFRSEPQYFYSHSKDLVY--N
LEEKEPSFIHHTLAKMEK-RRIIKALITQNIDMLHRKAGSCNVIEIHGSAMESTCLSCGKKFPYERTVQEIPKC-SCN--GILKPDIIFFGEMLETITKA
MLESSIADLFVVIGSSLLVQPAASLPFYAIRNGGKLVIVNDIPTPLDR-AYLKYDDLEDVFNG-LEKHF----------
>tr|W9E060|W9E060_METTI NAD-dependent protein deacetylase, SIR2 family OS=Methanolobus tindarius DSM 2278 GN=MettiDRAFT_2829 PE=4 SV=1
--------------------------------------TSENCVFLSGAGISTFSGIPDFRGSNGLYA-YDANKIFDLAYFHKNPSYFYTHAREFIY--D
LDTKEPNLIHRTLAIMEK-KGYLSSVITQNIDLLHQKAGSKNVIEIHGSPINHRCLSCGENYSYAVLLEKVPHC-RCS--GLIKPDITFFGEMLTAITNA
LEASSKADLFVVIGSSLVVQPAASLPLYSLKGGGKLVIVNNMATPLDE-AYLKYDELGDFFNH-LSSYF----------
>tr|L0KV50|L0KV50_METHD NAD-dependent protein deacetylase, SIR2 family OS=Methanomethylovorans hollandica (strain DSM 15978 / NBRC 107637 / DMS1) GN=Me
--------------------------------------SSSHCVFLSGAGISTLSGIPDFRGSKGIYK-FDADKIFDIHYFRKDPAYFYTHGREFIY--N
LEEKEPNIIHRMLAKLED-EGMVKSIITQNIDMLHQKAGSRRVIEIHGSPAQHTCLHCGKKFPYEPIVHHVPKC-RCG--GLVKPDIVFFGEMLNSFSQA
ISESSQADLMVVIGSSLVVHPAASLPLNAIKHGCRLVIVNNMPTPLDE-AYLRYTDLEEVFRY-LEKEI----------
>tr|Q12Y78|Q12Y78_METBU NAD-dependent deacetylase, Sir2-like OS=Methanococcoides burtonii (strain DSM 6242 / NBRC 107633 / OCM 468 / ACE-M) GN=Mbur_062
--------------------------------------NSEYCVVLTGAGVSTFSGIPDFRGRSGVYN-FDADLIFSIDHFNKDPAYFYAHSKSFIY--D
LEHRQPSIVHSVLSKLEE-KGIIKAIITQNIDMLHQKAGSKNVIEVHGSPQEHVCLACGKKYSYEELLKAFPLC-ECG--GLVKPDIVFYGEMLDTIEKA
IQESSKADLMLVLGSTLVVQPAASLPLYTIENGGELVIVNDMKTPLDG-AKRLYDDLGDVFIS-VAEYF----------
>tr|A0A0E3SR85|A0A0E3SR85_METMT NAD-dependent protein deacetylase of SIR2 family OS=Methanococcoides methylutens MM1 GN=MCMEM_1313 PE=4 SV=1
--------------------------------------NSKYCVILTGAGISTLSGIPDFRGKDGIYN-FDADLIFSIDYFNEDPSYFYTHSRELIY--D
LERKEPNIIHKALAELER-RGIVKAVITQNIDMLHQRAGSENVIEVHGSPARHTCLACGKKYSFEGLLEKVPMC-ECG--GLIKPDVVFYGEMLDVIEKA
IEESSRADLIIVLGSTLVVQPAATLPLYTLDHGGELVIVNNMPTPLDD-ARSRYDDLVEVFNY-LNEEM----------
>tr|E3CZY3|E3CZY3_9BACT Silent information regulator protein Sir2 OS=Aminomonas paucivorans DSM 12260 GN=Apau_0481 PE=4 SV=1
--------------------------------------SSRRVAVLSGAGLSTKAGIQDFRGPQGLYR-SDPERIFDIDHFFRNPGFFFRFHREFLD--L
LDRVQPTGAHRFFARLEE-EGVLSGIVTQNIDGLHQKAGSRNVLEIHGGVRGNTCTGCGARYDLAELLAAVPRC-RCG--GIVKPDIVFFGEGV-ALGAC
QALMEEADLLFVVGSSLVVTPAALLPSAC---PGRIVVVNKGEISFSYRVSLHAEEDLDTFFQRVEKAY----------
>tr|G8QVK3|G8QVK3_SPHPG NAD-dependent protein deacetylase, SIR2 family OS=Sphaerochaeta pleomorpha (strain ATCC BAA-1885 / DSM 22778 / Grapes) GN=SpiGr
--------------------------------------NAKKMTVFTGAGVSTLSGIPDFRGKNGLYS-LPVEQILNISFFEKHPEIFYEWAREFWY--H
LEDYKPNVVHTTLAKMEQ-KGLVAGLYTQNIDMLHKKAGSKKVYEVHGSAEHHHCHTCNKYYCYGAQVQAVPFC-QCG--GIVKPDIVFYGENLLILARA
YEQFSHSDLCLVLGSSLTVQPAASFPYYATSNGCPLVIVNAQKTSQDG-ASLRFEDLKQTFLA-LDSWL----------
>tr|F4GJ74|F4GJ74_SPHCD NAD-dependent deacetylase OS=Sphaerochaeta coccoides (strain ATCC BAA-1237 / DSM 17374 / SPN1) GN=Spico_0486 PE=4 SV=1
--------------------------------------SSHRMVIFTGAGVSTMSGIPDFRGTHGAYS-MDVEDILSIDFFKRSPEIFYAWARDVWY--R
LDEYEPTIVHRVVAELEA-KGYIKDVWTQNIDMLHQKAGSRVVHEIHGSPARHHCIQCNAFRSYDPEVLAVPLC-RCG--GVVKPDIIFYGENLQQLMMA
REEFFHVDLCVVMGSSLVVQPAASFPLLSCRGGGKLVIVNAQPTPLDA-AFLRFPDLEAVCAD-IQAWL----------
>tr|G8QQQ9|G8QQQ9_SPHPG NAD-dependent protein deacetylase, SIR2 family OS=Sphaerochaeta pleomorpha (strain ATCC BAA-1885 / DSM 22778 / Grapes) GN=SpiGr
--------------------------------------NSKNTSVYTAFEVSRLSGVPDYRLPHGNET-IQMDRLLSWDYFISRPEVVYAWARDMWF--S
MEDYEPNRIHTLLSEGMQ-SGRIKNVITENIDMLLQRAGIGNPLELKGSPYLSYCMKCGKPFLYTPVVKEIPYC-LCG--TIVRPSILFIDEPMPIMKKA
IPAFSFCNLCIVIGSPTPRKEI--IDLFKTVRKDKLVVLSPRETCIDD-AFIKLNDIEGVMR-ELETSF----------
>tr|F0RZ34|F0RZ34_SPHGB NAD-dependent deacetylase OS=Sphaerochaeta globosa (strain ATCC BAA-1886 / DSM 22777 / Buddy) GN=SpiBuddy_1416 PE=4 SV=1
--------------------------------------NSRSTVVLTGAGISTLSGIPDFRSSSGVYA-YQVEEILSISFFKHNPEIFYEWAKEFWY--K
LDLYQPNAVHTALALLEQ-KGYLEGLFTQNIDMLHKKAGSKKCYEVHGSAEHHHCTNCNAYYSYQPLVLAVPLC-DCG--GVIKPDIVFYGENLFILSRA
YEMFNHAQLCIVLGSSLVVQPAASFPAYTVHRGAPLVIVNAQKTSFDG-ATIKFNDLQQWGQA-LLPWI----------
>tr|Q3A6W7|Q3A6W7_PELCD NAD-dependent protein deacetylase, Sir2 family OS=Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1) GN=srtN PE=4 SV=1
--------------------------------------RSRCVVTLSGAGISTAAGIPDFRGPQGLYV--DPEKVFDIDWFHREPRYFYEFTRDFVS--T
VKAIRPTFTHRFLAGLEK-AGGLAGLITQNIDMLHQLAGSRKVIDLHGSYRSAQCLFCGKSYEALSTSSKLAYC-ACN--SVLKPDIVFFGEMV-AFEAA
EQLIAQCDLLLVLGSSLKVTPASLLPYHT---QATTVVVNRGAVM---PHRFFVDGDLDVYFRAVAKHL----------
>tr|A1AML5|A1AML5_PELPD Silent information regulator protein Sir2 OS=Pelobacter propionicus (strain DSM 2379) GN=Ppro_0957 PE=4 SV=1
--------------------------------------NSKSMVALTGAGISTAAGIPDFRGPKGLYV--DPELVFEIDNFQRAPQYFYEFTSDFAT--A
VRDVAPTFTHRFLAQQEQ-AGQLEGVITQNIDILHQMAGSRNVLELHGSYRSATCQSCRTRLHELAGSSHVVHC-SCD--GLLKPDIVFFGEAV-GFGRA
EAMVAACDLLLVLGSSLNVTPASLLPYST---SAPTVIVNRGSVM---PNRYFVDEDLDDYFTKVADHV----------
>tr|Q22ZC3|Q22ZC3_TETTS SIR2 family transcriptional regulator OS=Tetrahymena thermophila (strain SB210) GN=TTHERM_00112480 PE=4 SV=1
--------------------------------------KYKQIAFLTGAGISVSAGIPDFRSPTGLYAESDPQKIFSIRYYQDNPLPFMQVIRDFFS---
R-EYHPTYAHKLIHQIYK-RKQLLINITQNIDGLELKTGISKVVQAHGHMRKAHCVNCNHIVNIEQNCKQKTQC-ICN--NLVKPKIVFFGEFLEFYQSR
D-ILPNSDCVVVMGTSLGVFPFANLINEVGTSVP-IYIINNKLPKNISNQIEFIQGDINEISKQIIDYI----------
>tr|A0A0N0G7Q9|A0A0N0G7Q9_PSEAV NAD-dependent deacetylase OS=Pseudomonas amygdali pv. lachrymans GN=AC499_0656 PE=4 SV=1
----------------------------------------MNILAITGAGLSVGSGLPTYRGAQGRYTEPV-EKIVSVDTLRNRPELLWKYWLAMHA--N
YAQATPSIGHYALKRLSE-AAGEYMEVTQNVDGLSLKAGVKNVIELHGSALRYVCQKCGYVHQLGEMAIP-PRCYPEN--ALIRPDVVMFGENVDNLFRA
IDYAAKTDLVIITGTTLGFYYLIAILATAVEAGAKVIYIDPEADREHPEKVIKATATADEALCRLVPAL----------
>tr|A0A0Q4NCB2|A0A0Q4NCB2_9PSED Uncharacterized protein OS=Pseudomonas sp. Leaf58 GN=ASF02_09100 PE=4 SV=1
-------------------------------------------MSITGAGISVGSGLPTYRGATGRYTLPV-EQIVSRQTLKENPELLWRHWHMLLM--A
LKSAAPSEAHKALKRISD-ASSDYLELTQNVDGLSLRAGLNRLVELHGSTHSYSCFRCGEKHELADMVLP-PRCYPAQ--APIRPDVVLFGENIENYNKA
MAHARSTNLLIISGTTLQFPYLMDPIAAALVNCATVLYVDPQASSDNLLEPEFRICSADVILPRIATF-----------
>tr|M2YJA7|M2YJA7_DOTSN Uncharacterized protein OS=Dothistroma septosporum (strain NZE10 / CBS 128990) GN=DOTSEDRAFT_181103 PE=4 SV=1
--------------------------------------SSQFVLALLGAGLSAS-GLPTFRG-GSCWRGRDIKSLATRTAFANDPVLVWQFYEQRRQQ--
ALWAQPNQGHIAIARLAHQ--EHFLAITQNIDGLSE-RGHSKLAPIHGSLFTAKCFDCTFETWNYLPLA-LPHCPQCRG-NLLRPGVVWFGEQLGLL---
-DDWPRVDLLLVVGTSCRVFPAAEYITRSE---AKIAHFNLEADEAY-SSDWFVQGDAAITLADVVNLA----------
>tr|A0A0E9NNQ3|A0A0E9NNQ3_9ASCO Uncharacterized protein OS=Saitoella complicata NRRL Y-17804 GN=G7K_5555-t1 PE=4 SV=1
--------------------------------------NSKRTLVLCGAGLSAS-GLPTFRG-GGLWRNHVATELVTPDAFEADPSLVWQFYHARRHA--
ALRAKPNAAHIALAEYTKA-PDKTFTISQNVDGLST-RGHDKLNLIHGNLFDLRCSGCGYVDKDNEVLT-LPMCPKCKT-NLLRPGVVWFGEGLDVI---
-DKAPRVDLMLVVGTSGVVWPAAGFAERVR---GKVAIFNMEVDQAE-PGDWVFEGPCEETIPEALQLT----------
>tr|A0A0C3D5N4|A0A0C3D5N4_9HOMO Uncharacterized protein OS=Scleroderma citrinum Foug A GN=SCLCIDRAFT_638646 PE=4 SV=1
--------------------------------------VSKNIIVIAGAGLSAS-GIPTFRDGGGLWRSLDATTLATPTAFAANPSLVWQFYHYRRVKVS
ALESKPNLAHHIIAKLS-V---SFHLITQNVDRLSV-RLQDSVFEMHGRIFDVKCTSCDYCVEDLNPLCALPRCSACH--ALARPGVVWFGETPYQL---
-NRL--ADMCLVVGTSSTVRPASLFASRVK---GKVAVFNLAPS----SADFVFRGPCETELGRVFPEL----------
>tr|A0A0C3QA80|A0A0C3QA80_9HOMO Uncharacterized protein OS=Tulasnella calospora MUT 4182 GN=M407DRAFT_123928 PE=4 SV=1
--------------------------------------SSKSLAILAGAGLSAS-GIPTYRGAGGLWRTHDAMSLATPEAFEDNPSLVWKFYHERREK--
AITALPNAAHKALASLY-LECPNPLFITQNVDSLSL-RLSESLLEMHGSLFRLRCTECERDYRDYSPLS-LPRCGSCG--GLLRPGVVWFGEVPEHL---
-SNK--CDLLLIVGTSSTVYPAAGFADIVG---GKTAVFNLERS----RADFLFIGPCEETLPQALGIA----------
>tr|I2FR13|I2FR13_USTH4 Related to NAD-dependent deacetylase Sirtuin 5 OS=Ustilago hordei (strain Uh4875-4) GN=UHOR_07790 PE=4 SV=1
--------------------------------------QARHPIALAGAGLSAS-GIPTFRGAGGLWRQHDALSLATPEAFKRDPSKVWQFYHYRRSV--
VISAAPNAAHLTIAKLLMD---SFHLITQNIDGLSA-RLQDSIIEMHGNLFKTICTNCGDAHFDRQPLS-LPRCTACG--GLLRPGVVWFGESIPEL---
-QPL--CDLILVLGTSSAVYPAAGFADRVH---GKVAVFNIDDPS-TTDLDWYFAGPIEKLLPEVLLSL----------
>tr|E6ZRI4|E6ZRI4_SPORE Related to NAD-dependent deacetylase Sirtuin 5 OS=Sporisorium reilianum (strain SRZ2) GN=sr15759 PE=4 SV=1
--------------------------------------QARHPVALAGAGLSAS-GIPTFRGAGGLWRQHDALSLATPEAFRRDASKVWQFYHYRRSV--
VLSAAPNAAHVSLARLLLE---SFHLVTQNVDGLSG-RLHNSIIEMHGNLFKTICTSCGDSRIDTQPLS-LPRCTGCG--DLLRPGIVWFGESIPDL---
-QPL--CDLILVLGTSSTVYPAAGFADMVH---GRVAVFNIDDPC-AADVDWYFAGRVEKMLPDVLGL-----------
>tr|A0A0D1CIL7|A0A0D1CIL7_USTMA Chromosome 17, whole genome shotgun sequence OS=Ustilago maydis (strain 521 / FGSC 9021) GN=UMAG_12006 PE=4 SV=1
--------------------------------------QARHPIALAGAGLSAS-GIPTFRGAGGLWRKHDALSLATPEAFQRDASKVWQFYHYRRSI--
VLSAMPNAAHLSIAKLLLS---SFHLITQNVDGLSS-RLQSSIIEMHGNLFKTICTSCGDSRIDMQPLS-LPRCTECN--GLLRPGVVWFGESIPEL---
-QSL--CDLILVLGTSSTVYPAAGFADVVH---GQVAVFNIEDAY-TTNADWYFAGPVEQLLPEVLGL-----------
>tr|A0A081CJE9|A0A081CJE9_CANAR DHS-like NAD/FAD-binding domain-containing protein OS=Candida antarctica GN=PAN0_014d5019 PE=3 SV=1
--------------------------------------QARHPIALAGAGLSAS-GIPTFRGAGGLWRSHDALSLATPEAFKRDPSKVWQFYHYRRSV--
VLAASPNAAHTTLAKLLIQ---SFHLVTQNVDGLSG-RLQGSILEMHGNLFKTICTSCGESRIDLDPLC-LPRCSGCN--GLLRPGVVWFGESIPEL---
-QSL--CDLILVLGTSSTVYPAAGFAQIVH---GQVAVFNIEQPS-D-DVDWHFVGPVETLLPQILSVT----------
>tr|A0A061H5T0|A0A061H5T0_9BASI Uncharacterized protein OS=Anthracocystis flocculosa PF-1 GN=PFL1_04295 PE=3 SV=1
--------------------------------------EAKRPVALAGAGLSAS-GIPTFRGAGGLWRQHDALSLATPEAFQRDPSKVWQFYHYRRTV--
CLAAKPNPAHMALAKLLAS---SFHLITQNVDGLSG-RMAANVLEMHGNIFKTICTRCRHSEMNYNPIA-LPRCRTCD--GLLRPGVVWFGESIPQL---
-EAI--CDLILVLGTSSTVYPAAGFAQQVR---GRVAVFNIDERN-DGLADWHFQGPVEELLPKALGLD----------
>tr|G3BFT4|G3BFT4_CANTC DHS-like NAD/FAD-binding domain-containing protein OS=Candida tenuis (strain ATCC 10573 / BCRC 21748 / CBS 615 / JCM 9827 / NBR
--------------------------------------HSKRIVALVGAGLSAS-GLPTFRGSQGLWKNFNMIDLATPDAFYIDPGLVWQFYSYRRHA--
ALKAHPNSGHLALARLSQVPSVEFVTITQNVDGLSI-RG-HKLHEIHGSLFDLRCTSCNYVDHDNDPLTSLPRCPACGD--LLRPGVVWFGESLQLL---
-DGF-PIDLMLVVGTSGTVYPANGYVDRVY---GKVAIFNTDIEDSV-EGVWGFRGDAAETLPQALDPL----------
>tr|C5MF30|C5MF30_CANTT Putative uncharacterized protein OS=Candida tropicalis (strain ATCC MYA-3404 / T1) GN=CTRG_04673 PE=4 SV=1
--------------------------------------KSKKIISLVGAGLSVS-GLPIVYGTQELYKNYNSIDLSTPDSFYIDPSLVWQYYSYKRYQ--
ALQASPNKGHIALSKLSHLDNIKYITITQNNDGLHG-QN-NKLFEIHGSLFDLKCTSCNFVDHNNHPLTSLPLCPICNE--LLRPGVVWFGESLNLI---
-DNFPSIDLILVIGTSGTVYPANSFIERVL---GKIAIFNIDIDEDI-PGVWGFKGDAAELLPIALKPL----------
>tr|M3JUV1|M3JUV1_CANMX Uncharacterized protein OS=Candida maltosa (strain Xu316) GN=G210_3059 PE=4 SV=1
--------------------------------------KSKKIIALVGAGLSVS-GLPIIHGTQSLYKNFNSIDLSTPDAFYIDPSLVWQYHSYKRYQ--
CLNASPNNGHIALSKLSQLEELAYLTITQNSDGLISDRG-GKLIEIHGSVFDLKCTSCNYVERGNHPLTSLPLFPVCGE--LLRPGVVWFGESLNLI---
-DNFPSIDLILVIGTSGTVYPANSFIERVL---GKIAIFNIDIDDDI-GGVWGFKGDAAALLPIALKPL----------
>tr|A8NIK3|A8NIK3_COPC7 Sirtuin OS=Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003) GN=CC1G_09430 PE=4 SV=1
--------------------------------------SSKQVAILAGAGLSAS-GIPTYRGGAI-WKNMDHDKLATVEGFEKDPVTCWQFHHMMRQL--
CLDATPNAAHRALASLV-VPDSPPLFITQNMDSLSP-RLDERLVEMHGNIFRQKCLQCKHVSTSTSHLALLPRCGRCG--GPLRPSVVWFGEIPEGL---
-ARH--TDMLIVVGTSCLVHPAAGFLKTVD---GKVAIFNYDAS----LADFLFLGKCEEVLPIALGIE----------
>tr|K9HC12|K9HC12_AGABB Uncharacterized protein OS=Agaricus bisporus var. bisporus (strain H97 / ATCC MYA-4626 / FGSC 10389) GN=AGABI2DRAFT_187357 PE=4
--------------------------------------RAKNVLILSGAGLSAS-GIATYRNANSLWNNFDPKKYATLEAFKDDPVGLWTFYHRRRSE--
YLLAKPNPAHYALGLLA-HRPSSIRHITQNIDALAL-RIEEAIVEMHGDIFVTRCISCQHINRSYPQLAQLPKCGRCG--GLLRPEVVWFGEVPPQS---
-ARM--CDMLLVVGTSSIVRPAADYAAQVK---GIVAVFNLGHS----EADFVFIGPCEETLPEVLQVK----------
>tr|K2SBJ5|K2SBJ5_MACPH NAD-dependent histone deacetylase silent information regulator Sir2 OS=Macrophomina phaseolina (strain MS6) GN=MPH_08615 PE=4 S
---------------------------------------SRRIMALFGAGLSAS-GVPTFRG-AGFWREYDCMTLATPGAFFRDPCLVWQFYNYRRHC--
ALKAKPNRAHVALAELAKK--PDYLAISQNIDGLCQ-RNHENLQPVHGSLFDIKCSNCSYVEKDNDPIVSLPHCPLCA--SLLRPDIVWFGESLSCV---
-HSW-KIDLMLVVGTTAQVYPAAGYIHAAV---ARIAVFNMEDSEEECEGDWFFKGDASKIVPEVLKEV----------
>tr|A8NVB6|A8NVB6_COPC7 Uncharacterized protein OS=Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003) GN=CC1G_06234 PE=4 SV=2
--------------------------------------KSTQLAILAGAGLSTS-GIPTFTGQGVPFTYSLDEKFATAQAFKEDPVRVWRFHHSIRKR--
CLNASPNAAHKALGALHADPTSSPLFITQNVDNLSL-DLSNRLIEMHGNIFRQECLQCRHVSTSSTNLADLPRCGHCK--GKLRPAVTWYGEIPQGL---
-GRY--TDMLIIVGASPLAHPAAGFIRTVE---GKVAVFHLEPS----DADWVFLGRCEEVLPRVLGLD----------
>tr|A0A0P5CPC4|A0A0P5CPC4_9CRUS NAD-dependent protein deacylase sirtuin-5, mitochondrial OS=Daphnia magna PE=4 SV=1
--------------------------------------KANAVVILTGAGVSAS-GVPTFRGAGGLWRIYSATDLATPSAFRSNPSLVWEFYHHRREN--
VASKHPNNAHKAIAEFEHR--KHVSVITQNIDELHQ-RGS-NILELHGSLFKTRC--CKKVESNYSPIC-LPRCKSCG--GLLRPYVVWFHENLIILH-I
LEKD-SCDLCLVVGTSSIVYPAAMFAPQV-AA-VPVAEFNMETTS---NFEFHFSGPCGELLPIALAP-----------
>tr|A0A0K6S9D7|A0A0K6S9D7_9ALVE Uncharacterized protein (Fragment) OS=Chromera velia CCMP2878 GN=Cvel_29124.t2 PE=3 SV=1
--------------------------------------EASRVLILTGAGVSAS-GIPTFRGAGGLWRQYQATDLATPQAFRNDPSLVWEFYHYRRDL--
VSKCEPNPAHLAIAAFQKK--RIVTVVTQNIDRLHQ-AGA-KVIELHGSLWLVKRETSGKVWEDRNPIC-LPHVVGRL--SLLRPAVVWFGEGLLTL---
-EAE-LCDLMIVAGTSSVVYPAAGFAPIV-AA-APIIEVNLESTA---MCTVGLQGKAGEILPALLGVE----------
>tr|S3BU99|S3BU99_OPHP1 Sir2 family histone OS=Ophiostoma piceae (strain UAMH 11346) GN=F503_06388 PE=4 SV=1
--------------------------------------RPARIMALCGAGLSAS-GLATFRGSAALWHTN-PMELATPEAFEADPGLVWRFYAYRRHT--
ALAAQPNAGHRALAALA-TGGPRFLCLTQNVDGLSE-RNHSSLHRMHGSLFDLRCTKCDYATENHDPLCKLPQC--DG--SLLRPGIVWFGERLQML---
-DQWDTVDLLLVVGTTAELSSALGFIDDA--E-AVVATITLDVESLQSEDDLAFVGSAADLLPLLLEPV----------
>tr|D3PHR0|D3PHR0_LEPSM NAD-dependent deacetylase sirtuin-5 OS=Lepeophtheirus salmonis GN=SIRT5 PE=2 SV=1
--------------------------------------RSKNIVVLTGAGISAS-GVPTFRGPGGYWRKYQAQNLATPEAFRADPSLVWEFYHYRREV--
MLSKQPNPAHIALARLEKKGLKKLIIITQNIDELHK-RGS-NILELHGSLFRVRC--CGIESLNYSPIC-LPSCTECG--GLIRPAVVWFGERLRIL---
-HDA-QCDLCLVVGTSSVVYPAAMLAPEA-AE-IAVAEFNVEPTP---EFKFHFAGPCGTTLPRALGLD----------
>tr|W3X4T1|W3X4T1_9PEZI Uncharacterized protein OS=Pestalotiopsis fici W106-1 GN=PFICI_06135 PE=4 SV=1
--------------------------------------KSRRIIAVLGAGLSVS-GLPTYRGATGLWRNHDATQIATPAAFRHDPGLVWQYTSHMRRL--
ALAAAPNDAHYALAELARR--PSFVTLSQNIDNLSP-RGHDQLKLLHGNLFNLRCADCGYVERGNDPITMLPQCPRCAT-SLLRPNIVWFGEALDLM---
-DAMEPIDLCLVIGTSGSVWPAAGYADLAK---ARIATVNIDISD-IKGVDWVFAGDAAAIVPRLFEPL----------
>tr|A0A0B7KD28|A0A0B7KD28_BIOOC Uncharacterized protein OS=Bionectria ochroleuca GN=BN869_000008858_1 PE=4 SV=1
---------------------------------------SRRILALCGAGLSAS-GLPTFRG-GGLWRNFEATNLATPGAFAMDPGLVWLFYGYRRHM--
CLKAKPNDAHKALAALARE--PNFLCLTQNVDNLSQ-RQHDRLFTLHGSLFDIKCS-CDWIERGNDPFC-LPKCPRCKQ-GLQRPGVVWFGESLDVI---
-DSF-PLDLMFVIGTSAIVSPAAGYIDKAK---ARIVVIDPRAEDLD-SGDFAFGQDAAKILPVLLEPI----------
>tr|A0A074YJ25|A0A074YJ25_9PEZI Uncharacterized protein OS=Aureobasidium subglaciale EXF-2481 GN=AUEXF2481DRAFT_6135 PE=4 SV=1
--------------------------------------SSKRILALLGAGLSAS-GLPTFRG-GGLWRSHDATSLATPEAFNADPVLVWQFYSYRRHM--
ALKARPNRAHLALAELARR-NPDFMTLSQNVDGLSQ-RKHEKLQLLHGSLFNVKCTSCSYQA-ENDPIVSLPKCPECHQ-GLLRPGVVWFGESLKVL---
-DTFSKIDLILVIGTSARVYPAAGYVDDAA---ARVAVINADPEDIPADKDWFFEGDAAQIVPDILKSV----------
>tr|A0A074VHH9|A0A074VHH9_9PEZI NAD-dependent deacetylase sirtuin-5 OS=Aureobasidium melanogenum CBS 110374 GN=M437DRAFT_55328 PE=4 SV=1
--------------------------------------SSKRILALLGAGLSAS-GLPTFRG-GGLWRTHDATSLATPEAFARDPALVWQFYSYRRHM--
ALKASPNRAHLALAELATK-HPGFLALSQNVDGLSQ-RRHEKLQLLHGSLFNVKCTSCSYHA-QNDPIVALPKCPECHE-GLLRPGVVWFGESLKVL---
-DKFWKIDLIMVIGTSASVYPAAAYVDDAA---ARVAVINADRADEPADNDWFFEGDAAQIVPDILKSV----------
>tr|A0A0G4LG82|A0A0G4LG82_9PEZI Uncharacterized protein (Fragment) OS=Verticillium longisporum GN=BN1708_003396 PE=4 SV=1
--------------------------------------NTPRILALCGAGLSAS-GLPTFRG-GGLWRRHDATRLATPEAFAADPALVWLFYAYRRHM--
ALAARPNPAHRALAALARA--PGFLCLTQNVDGLSQ-RGHAQLRALHGNLFGLRCSGCGYEEEENDPLVLLPSCPRCS--SLLRPGVVWFGETLALL---
-DGW-TIDLVLVVGTSAQVFPAAAYVELGA---AKVCVVDLEVGR---DVDFVFEGDAAVLLPRMLEPL----------
>tr|A0A0A3CNR7|A0A0A3CNR7_CANAX Uncharacterized protein OS=Candida albicans P37005 GN=MEU_00260 PE=3 SV=1
--------------------------------------KCRKIIALVGAGLSAS-GLPTFRGSQGLWKNFNMIDLATPDAFYIDPGLVWQFYSWRRYG--
ALRAKPNKGHYALSKLSHKNSDEYITITQNVDGLSS-RG-DSLYEIHGSLFDLKCTSCNYIDHNNQPLTSLPSCPVCHD--LLRPGVVWFGESLNLI---
-DSF-SVDLILVIGTSGTVYPANSYVERVL---GKVAIFNTDIEDNI-EDTWGFKGDAAELLPIALKPL----------
>tr|A0A0B7JWQ6|A0A0B7JWQ6_BIOOC Uncharacterized protein OS=Bionectria ochroleuca GN=BN869_000005545_1 PE=4 SV=1
---------------------------------------STRILALCGAGLSAS-GLSTYRG-GGLWRNHSPTSLATPEAFEDDPALVWLFYAWQKHM--
AIKAVPNPGHYALAELAKR--EGFLCLTQNTDGLSP-RGHDQLRIMHGNILDLKCSDCGYVEKDNDPPCLLPHCPQCKT-GLLRPGVVWFGEAVGML---
-DGW-SIDLMLVIGTGVTVQPAANYVRQAR---AAVAVVNPDADA---KKDFFFQGDAAELLPVLLEGV----------
>tr|A0A0G2HRA4|A0A0G2HRA4_9PEZI Putative sir2 family histone OS=Diaporthe ampelina GN=UCDDA912_g09373 PE=4 SV=1
---------------------------------------SNRILALCGAGLSAS-GLPTFRG-GGLWRNHEPTSLATPEAFEKDPALVWLFYAWRRHM--
CLKAQPNKGHQALAELAKK--EDFICLTQNVDGLSS-RGHDRLRLLHGSILDLKCFDCGYVERDNDPLCLLPHCPKCRK-GLLRPGVVWFGERLDML---
-DGW-PVDVMLVVGTAAVVYPAAGYTQKAS---AVVAVINPDGDA---PGDFFFQGDAAEILPELFAKV----------
>tr|A0A0P4UFA3|A0A0P4UFA3_ROSNE Putative nad-dependent deacetylase sirtuin-5 OS=Rosellinia necatrix GN=SAMD00023353_3400790 PE=4 SV=1
---------------------------------------SHRILALCGAGLSAS-GLPTFRG-GGLWRNHEPTALATPGAFAADPALVWLFYAWRKHM--
ALRARPNRGHRALAELAKR--DGFLCLTQNVDGLSQ-RGHSQLRLLHGSILDVRCADCGYVRRDDDPPCLLPHCPRCVS-GLLRPGVVWFGEALTML---
-ENW-TVDLMLVVGTAAAVYPAAGYTRKAR---AVVAVVNPDPDA---GADFFFQGSADEILPLLFEGV----------
>tr|C4Y4Q6|C4Y4Q6_CLAL4 Putative uncharacterized protein OS=Clavispora lusitaniae (strain ATCC 42720) GN=CLUG_02628 PE=3 SV=1
--------------------------------------SSKRIVALVGAGLSAS-GLATFRGSQGLWKNFNMIDLATPDAFYIDPGLVWQFYSWRRYE--
ALKAQPNAGHLALARLSRLRSKKFITITQNVDGLSA-RG-KTLYEIHGSLFELRCTSCTHVERGNVPLTSLPKCPVCQS--LMRPGVVWFGESLRVL---
-DTF-PVDLILVIGTSGTVYPANSYVDIVQ---GSVAIFNTDIDQDV-AKTWGFKGDAAELLLIALSPL----------
>tr|A0A0L0NQP0|A0A0L0NQP0_9ASCO Uncharacterized protein OS=Candida auris GN=QG37_07269 PE=3 SV=1
--------------------------------------NLKRIVALVGAGLSAS-GLPVFRG-QGLWKNFNMIDLATPDAFYIDPGLVWQFYAWRRHM--
ALAAQPNAGHRALAALSQD-SKEFLTITQNVDGLLT-RGHRHLYEIHGSLFELRCTSCTHRE-ENDPLTLLPPCPVCG--SLMRPGVVWFGESLRAL---
-DTFGPVDLILVIGTSGTVYPANGYVERVQ---GKVAIFNTDIEEDVVADTWGFQGDAAKLLPELIGTQ----------
>tr|G3AF83|G3AF83_SPAPN Transcriptional regulatory protein OS=Spathaspora passalidarum (strain NRRL Y-27907 / 11-Y1) GN=SPAPADRAFT_57964 PE=3 SV=1
--------------------------------------KSKKIVALVGAGLSVS-GLPTFRGSQGLWKNFNMIDLATPDAFYIDPGLVWQFYSWRRYT--
ALKAKPNKGHYALAKLSQMSDLTYITITQNVDGLSS-RG-ENLYEIHGSLFDLKCTSCNFVDHNNQPLTSLPQCPVCKDGSLLRPGVVWFGESLSLI---
-DNFSPVDLILVIGTSGTVYPANSYVDRVL---GKVAIFNTDIENDI-KDTWGFKGDAAELLPLALKPL----------
>tr|Q6BVM7|Q6BVM7_DEBHA DEHA2C01386p OS=Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) GN=DEHA2C01386g PE=3 SV=2
--------------------------------------KSKRIVALVGAGLSVS-GLPTFRGSQGLWKNFNMIDLATPDAFYIDPGLVWQFYSWRRIN--
ASKAKPNKGHLALAKLSKLSNIEFMTITQNVDGLSI-RG-EKLHEIHGSLFDLRCTSCNYVDHDNNPLTSLPQCPVCEDGSLLRPGVVWFGESLQTI---
-DNF-KIDLILVIGTSGTVYPANSYVDRIL---GKVAIFNTDIESEI-KDTWGFQGDAAELLPIALKPL----------
>tr|G8YG66|G8YG66_PICSO Piso0_002864 protein OS=Pichia sorbitophila (strain ATCC MYA-4447 / BCRC 22081 / CBS 7064 / NBRC 10061 / NRRL Y-12695) GN=Piso0
--------------------------------------TSRRIVALVGAGLSVS-GLPTFRGSQGLWKNFNMIDLATPDAFYIDPGLVWQFYSWRRFN--
ALQARPNKGHAALAKLSELDGIEYITISQNVDGLLR-RG-DNLYEIHGSIFELRCTSCNYVARDNHPLTSLPQCPVCNDGSLLRPGVVWFGEPLGPI---
-DNF-DVDLVLVIGTSGTVYPANSYVDRIA---GSVAVFNTDIEQEI-SKTWGFKGDAAVLLPLTLKPL----------
>tr|A3LRA1|A3LRA1_PICST Transcriptional regulatory protein OS=Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) GN=SI
--------------------------------------TCRKIVALVGAGLSVS-GLPTFRGSQGLWKNFNMIDLATPDAFYIDPGLVWQFYSWRRYN--
ALQAKPNKGHLALSALSNLSNLEYITITQNVDGLSS-RG-ENLYEIHGSLFNLNCTSCNYVDRNNHPLTSLPQCPVCKDGSLLRPGVVWFGESLNVM---
-DNF-SVDLILVIGTSGTVYPANSYVDRVV---GKVAIFNTDIEEDI-KDTWGFRGDAAELLPIALKPV----------
>tr|A0A074XQL6|A0A074XQL6_AURPU DHS-like NAD/FAD-binding domain-containing protein OS=Aureobasidium pullulans EXF-150 GN=M438DRAFT_266268 PE=4 SV=1
--------------------------------------NSASIIALVGAGLSAS-GLSTFQG-GGLWRSYDPTTLATPEAFASNPELVWQFYSHRRHC--
ATLAQPNLAHHALAEASRR--PGLLTLSQKIDDLSE-RGHEQILHLHGSLFQSRCVDCGYSRSGMSSQM-LPTCPNCT--RLLRPGVVWFGEPLEVL---
-RNWAKVDLMLVIGTSAQVYPAAGYINVAL---ARICVVNTNRDHESNEDDWFFQGDAAVILPTLLQPF----------
>tr|G7XG35|G7XG35_ASPKW SIR2 family histone deacetylase OS=Aspergillus kawachii (strain NBRC 4308) GN=AKAW_04074 PE=4 SV=1
--------------------------------------GCRRVIALLGAGISAS-GLPTFRG-GGLWRSYDATDLATPEAFDANPDLVWQFYSYRRHM--
ALKAQPNRAHYALAELARK-NKDFITLSQNVDGLSQ-RRHHQLHLLHGSLFTVKCTSCSYSR-EDDPIVSLPHCPECKD-GLLRPGVVWFGESLHTI---
-DEWGNVDLILVVGTSSRVYPAAGYVDKAS---ARVAVVNMDRNDVGSPGDWFFEGDAGTIVPEILKGV----------
>tr|W6R0H8|W6R0H8_PENRO NAD-dependent deacetylase, sirtuin family OS=Penicillium roqueforti FM164 GN=PROQFM164_S04g000193 PE=4 SV=1
--------------------------------------GCKRIVALLGAGISAS-GLPTFRG-GGLWRSHDATSLATPEAFDETPGLVWHFYSYRRHM--
ALQADPNKAHYALAELSRR-NEDFITLSQNVDGLSQ-RNHKQLHLLHGTLFTVKCTNCDYTE-DNDPIVSLPQCPKCKD-GLLRPGVVWFGEPLKTL---
-DKWGPIDLCLVIGTSARIWPAAGYVHEAS---ARVAVCNMDRKDT-PNGDWFFQGDAGVIIPEILKSV----------
>tr|Q4WMP3|Q4WMP3_ASPFU SIR2 family histone deacetylase, putative OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) GN=A
--------------------------------------GCKRILALLGAGISAS-GLPTFRG-GGLWRSYDATDLATPEAFEANPDLVWQFYSYRRHM--
ALKANPNRAHHALAELARK--RDFITLTQNVDGLSQ-RNHEQLHLLHGSLFTVKCTSCNYVRENDDPIVSLPHCPECKE-GLLRPGVVWFGESLHTL---
-DKWGPVDLILVIGTSSRVYPAAGYVDKAA---ARVAVVNMDRNDVGYKGDWFFQGDAGVIVPEILQGV----------
>tr|Q5BCE8|Q5BCE8_EMENI SIR2 family histone deacetylase, putative (AFU_orthologue AFUA_6G09210) OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / C
--------------------------------------GSKRIMALLGAGLSAS-GLPTFRG-GGLWRSYDATELATPEAFEANPDLVWQFYSYRRHM--
ALKAKPNKAHYALAELARR-KREFITLSQNVDGLSQ-RNHEQLHLLHGNLFTVKCTSCKYVRENDDPIVSLPRCPECKE-GLLRPGVVWFGESLQTL---
-DNWGKIDLMLVIGTSSRVWPAAGYAEQAA---ARVAVVNMDPNDMGKSKDWFFQGDAGVIVPEILKSV----------
>tr|A0A060T570|A0A060T570_BLAAD ARAD1B08184p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B08184g PE=3 SV=1
--------------------------------------GARRILALVGAGLSAS-GLATFRG-GGLWHGYDATELATLDAFQTDPALVWQFYACRRAQ--
ALKAKPNKGHYALAELARRGPSRFLTLTQNVDGLST-RGHDSLVHLHGDLFTVHCTSCTYRGRNENPISTLPKCPRCK--GLLRPGVVWFGETLSAV---
-DDFGEVDLILVIGTSGVVWPAASYIEQVL---GQVAVFNVEAP--S-NEDWLFLGDAAEMLPKALEPI----------
>tr|A0A0D2IJ44|A0A0D2IJ44_9EURO Rhinocladiella mackenziei CBS 650.93 unplaced genomic scaffold supercont1.3, whole genome shotgun sequence OS=Rhinocladiella ma
--------------------------------------NSKRIVALLGAGLSAS-GLPTFRG-GGLWRTYDATMLATPEAFQSDPGLSWQFYSYRRHM--
ALNAKPNRAHLALAELARR-NPNFITLSQNVDGLSP-RGHEQLKLLHGSLFDVKCWDCGYSRQNDDPIVSLPQCPSCQK-NLLRPGVVWFGEALDVM---
-SAWERIDLMLVIGTSSKVYPAAGYTQMAQ---ARVAVINLDPADA--KRDWFFQGDAAVIVPDILKSV----------
>tr|W3WQX6|W3WQX6_9PEZI Uncharacterized protein OS=Pestalotiopsis fici W106-1 GN=PFICI_11652 PE=4 SV=1
---------------------------------------SDRVMALCGAGLSVS-GLPTFRG-GGLWREFDSTDLATPDAFEDDPALVWLFYAWRRHM--
ALNAQPNAGHYALAELAKK--KNFLCLTQNVDGLSP-RGHEGIRMLHGNLLDVKCWDCGYIEHNVDPLCLLPHCPACERKNLLRPGVVWFGEALGML---
-DNW-KVDVMLVVGTAAAVYPAAGYTRKAR---AVVAVVNPDPTS---ENDFFFQGGADEFLPKLFEDV----------
>tr|A0A0D2GJM3|A0A0D2GJM3_9EURO Unplaced genomic scaffold supercont1.5, whole genome shotgun sequence OS=Fonsecaea pedrosoi CBS 271.37 GN=Z517_08614 PE=4 SV=1
--------------------------------------SSTRIVALLGAGLSAS-GLPTFRG-GGLWRTFDATMLATPEAFQQDPGLSWQFYSYRRHM--
ALNAKPNRAHLALAELARR-NPNFITLSQNVDGLSP-RGHSQLKLIHGNLFDVKCWDCGYFRKNDDPIVSLPQCPSCKK-NLLRPGVVWFGESLDVM---
-NEYGKIDLMLVIGTSAKVYPAAGYTNIAA---ARVAVINMDRSDA--KHDWFFEGDAAVIVPEILKSV----------
>tr|A0A0D1WS96|A0A0D1WS96_9EURO Uncharacterized protein OS=Exophiala mesophila GN=PV10_06495 PE=4 SV=1
--------------------------------------SSKRICALLGAGLSAS-GLPTFRG-GGLWRTYDATDLATPEAFQSDPALSWQFYSYRRHM--
ALNAKPNRAHLALAELARR-NPQFITLSQNVDGLSP-RGHDQLKLLHGNLFDVKCWDCGYHRQNDDPIVSLPQCPQCNK-NLLRPGVVWFGESLHVV---
-SAWDKVDLILVIGTSSKVYPAAGYTQVAQ---ARVAVINMDPADA--NQDWLFQGDAAVIVPDLLKSV----------
>tr|A0A072PUS2|A0A072PUS2_9EURO Uncharacterized protein OS=Exophiala aquamarina CBS 119918 GN=A1O9_01490 PE=4 SV=1
--------------------------------------SSRRICALLGAGLGAS-GLPTFRG-GGFWRTYDATVLATPGAFRTDPALVWQFYSYRRHM--
ALNAKPNRAHLALAELARR-NPDFITLSQNVDGLSP-RGHDQLKLLHGNLFDVRCWDCGYRVKNDDPIVSLPQCPSCKK-NLLRPAVVWFGETLDVL---
-NAFEKIDLMLVIGTSSKVYPAAGYTSMAN---ARVAVINVDPADA--DRDWFFQGDAAAIVPEILKPV----------
>tr|A0A017S683|A0A017S683_9EURO Putative SIR2 family histone deacetylase OS=Aspergillus ruber CBS 135680 GN=EURHEDRAFT_415834 PE=4 SV=1
--------------------------------------GCKRIMALLGAGISAS-GLPTFRG-GGLWRSYDATDLATPEAFEGNPDLVWQFYGFRRHM--
ALKAKPNRAHYALADLARK-NKDFITLSQNVDGLSQ-RNHEQLHLLHGSLFTIKCTSCNYVSENNDPVVSLPHCPKCKE-GLLRPGVVWFGEPLQVF---
-DEFGPVDLILVIGTSSKVYPAAGYVDEAA---ARVAVVNMDSNDVGRKGDWLFQGDAGVIVPEILGSE----------
>tr|W9YJ35|W9YJ35_9EURO Uncharacterized protein OS=Capronia epimyces CBS 606.96 GN=A1O3_02332 PE=4 SV=1
--------------------------------------SARRIVALLGAGLSAS-GLPTFRG-GGLWRTYDATRLATPGAFKADPGLSWQFYSYRRHM--
SLNAKPNRAHLALAELARR-NSNFLTLSQNVDGLSP-RGHEQLKLLHGSLFDVKCWDCGYIRRNDDPIVSLPHCPQCKE-NLLRPGVVWFGETLDVL---
-SRWENIDLILVIGTSSRVYPAAGYTEMAE---ARVAVINMDPGDA--KHDWFFEGDAATIVPEILESV----------
>tr|A0A0D2AYH3|A0A0D2AYH3_9PEZI Uncharacterized protein OS=Verruconis gallopava GN=PV09_04526 PE=4 SV=1
--------------------------------------SSKRILALLGAGLSAS-GLPTFRG-GGLWRTHDAMDLATPEAFDADPGLVWQFYSYRRHQ--
ALKAKPNRAHYALAELAKKGAEGFTCLSQNVDGLSQ-RGHNSLQLLHGSLFDIKCTDCKYTEQDNDPIVALPHCPQCEK-GLLRPGVVWFGEMLKTI---
-DEWDKIDMIMVIGTSARVYPAAGYVQRAG---ARVAVVNTDVNDAPEKGDWFFVGDASVLVPEMLKPV----------
>tr|C5FQF7|C5FQF7_ARTOC NAD-dependent deacetylase sirtuin-5 OS=Arthroderma otae (strain ATCC MYA-4605 / CBS 113480) GN=MCYG_04929 PE=4 SV=1
--------------------------------------KSKRILALVGAGLSAS-GLPTFRG-GGLWRSHRAPDLATPEAFGVDPGLVWQFYSYRRHM--
SLVAHPNKGHYALAALARK--PHFWTLTQNVDGLSE-RNHSQLHRLHGSLFTVKCSSCTYSRDNDDPLVSLPHCPQCSS-ALLRPGVVWFGEELDTL---
-EKFGPVDLVLVIGTSAQVFPAALYVEHGD---ARVAVINMDATHVPQATDWLFQGDASVILPEILKDI----------
>tr|W7I3B2|W7I3B2_9PEZI Uncharacterized protein OS=Drechslerella stenobrocha 248 GN=DRE_03894 PE=4 SV=1
---------------------------------------SRRILALCGAGLSAS-GLATFRG-GGLWKTHDAMSLATPQAFTKDPSLVWQFYSARRQA--
AFSAKPNPAHRALAALSIK--KDFITVTQNVDGLSP-RGHGQLFPVHGSLSTVKCTGCNYVEFNNMALTALPKCSKCS--SLLRPGVVWFGETLDLV---
-NDW-PIDLCLVIGTSGRVWPAAGYIQRCE---AKVAIINMDIWNDP-HADWLFEGDCATILPEILEPI----------
>tr|S8AF44|S8AF44_DACHA Uncharacterized protein OS=Dactylellina haptotyla (strain CBS 200.50) GN=H072_4556 PE=4 SV=1
---------------------------------------SKRILALCGAGLSAS-GLATFRG-GGLWKTHDAMSLATPNAFVKDPSLVWQFYSARRQA--
AFSAKPNPAHLALAALAVK--SDFITVTQNVDGLSP-RGHLQLQPVHGSLSTIKCTSCNYIQYDNMALTNLPHCPKCTT-GLLRPGVVWFGESLHVL---
-DEW-PIELCLVIGTTGMVWPAAGYIGQCE---ARVAIINMEIDDDP-YADWLFKGDCAQILPQILEPV----------
>tr|A0A0D2B0P8|A0A0D2B0P8_9EURO Uncharacterized protein OS=Exophiala oligosperma GN=PV06_04047 PE=4 SV=1
--------------------------------------SSKRIVALLGAGLSAS-GLPTFRG-GGLWRTYDATVLATPEAFESDPGLSWQFYSYRRHM--
ALNAKPNRAHLALAELARR-NPDFITLSQNVDGLSP-RGHSQLKLLHGNLFDVKCWDCGYYRKNDDPIASLPQCPQCQK-NLLRPAVVWFGESLDVM---
-SEWEAIDLIMVIGTSSKVYPAAGYTDMAK---ARVAVINMDRGDA--DRDWFFEGDAAVIVPEILKSV----------
>tr|A0A0D1YC63|A0A0D1YC63_9EURO Uncharacterized protein OS=Exophiala sideris GN=PV11_08050 PE=4 SV=1
--------------------------------------SSKRIVALLGAGISQS-GLPTFRG-GGLWRTYEATMLATPEAFQADPALSWQFYSYRRHM--
ALNANPNRAHLALAELARR-NPNFITLSQNVDGLGP-RGHEQLKLLHGNLFDVKCWDCGYYRKNDDPIVSLPQCPQCKK-NLLRPGVVWFGEALDVM---
-EEWEKIDLMLVIGTSAKVYPAAGYINMAA---ARVAVINMDRGDA--KQDWFFEGDAAVIVPDILESV----------
>tr|W9YRG7|W9YRG7_9EURO Uncharacterized protein OS=Capronia coronata CBS 617.96 GN=A1O1_00277 PE=4 SV=1
--------------------------------------SSKRIVALLGAGISAS-GLPTFRG-GGLWRTYDATMLATPEAFEADPGLSWQFYSYRRHM--
ALNANPNRAHLALAELARR-NPDFLTLSQNVDGLSP-RGHAQLKLLHGSLFDVKCWDCGYIRRNDDPIVSLPHCPQCKK-NLLRPGVVWFGESLDVM---
-SDWEQIDLMLVIGTSSKVYPAAGYTQLAA---ARVAVVNMDRGDA--KRDWFFEGDAATIVPEILKSV----------
>tr|A0A0F8VKU3|A0A0F8VKU3_9EURO Uncharacterized protein (Fragment) OS=Aspergillus rambellii GN=ARAM_003438 PE=4 SV=1
--------------------------------------RSKRILALLGAGLSAS-GLPTFRG-GGLWRSYDATELATPEAFEANPDLVWQFYSYRRHM--
ALKAEPNRAHLALAELARR-NKDFVTLSQNVDGLSE-RQHEQLHLLHGNLFTVKCTSCKYSRSDEDPIVSLPQCPECEG-GLLRPGVVWFGESLHTL---
-DKWDKIDLILVIGTSARVYPAAGYVDEAR---ARVAVINMDQNDVGKSNDWFFQGDAGVVVPDILKAV----------
>tr|A0A0J9XCF8|A0A0J9XCF8_GEOCN Similar to Saccharomyces cerevisiae YDL042C SIR2 Conserved NAD+ dependent histone deacetylase of the Sirtuin family involved in
--------------------------------------KSKRILALVGAGLSAS-GLPTFRG-GGLWRTYAAVDLATPDAFLNDPALVWQFYAYRRHA--
ALKAKPNRGHLALAMLARR--PEFLTLTQNVDGLST-RGHDKLLCLHGDLFTLKCTSCSYIQTNNDPLTNLPLCPACRV-GLLRPGVVWFGESLSVV---
-DDFPPVDLILVIGTSGSVWPAAGYVEQVM---GKVAVFNIDRDSQS-FEDWIFEGDAAETLPVALEPI----------
>tr|W6MI61|W6MI61_9ASCO Uncharacterized protein OS=Kuraishia capsulata CBS 1993 GN=KUCA_T00002075001 PE=3 SV=1
--------------------------------------RCKTILALVGAGLSAS-GLDTFRG-GGLWNNYNAMDLATPDAFERDPCLVWQFYAYRRHC--
ALKAKPNSGHKALSQLSRLSRLSFLTLTQNVDGLSA-RGHRALLELHGSLFSVKCTSCAYKNDFNDPLVSLPHCPRCKT-GLLRPGVVWFGEPLRVI---
-DEFKKVDLMLVIGTSLTVWPAAGYVDMVS---GRIAIFNTETSS---ECEWSVEGNAAETLPKALEPL----------
>tr|Q6C8C7|Q6C8C7_YARLI YALI0D20724p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D20724g PE=4 SV=1
--------------------------------------SSRKILALVGAGLSQS-GLPTFRG-GGIWRNYDAAELATPEAFHNDPSTVWQFYAHRRHM--
SLKAKPNPGHYALAELARR-RGRFLTLTQNVDGLSS-REHEALLKLHGDLFALKCTSCSYTTEDNDPLT-LPTCPHCKE-GLLRPGVVWFGESLKVM---
-DEFEDVDLIIVVGTSGSVWPAAGYVERVL---GKVAIFNMEIDHYQYIEGWAFKGNASEWLPKALEPV----------
>tr|W1Q816|W1Q816_OGAPD NAD(+)-dependent histone deacetylase OS=Ogataea parapolymorpha (strain DL-1 / ATCC 26012 / NRRL Y-7560) GN=HPODL_02735 PE=4 SV=
--------------------------------------NCKTILALVGAGLSAS-GLSTFRG-GGLWKQYNAIDLATPDAFLDDPGLVWQFYAYRRHK--
ALQAQPNLGHYVLAELSKL-NINFLTITQNVDGLSQ-RHHGKLLEFHGSLFGMRCTNCSYEEQNNDPLC-LPHCPACKV-GLLRPAVVWFGESLQII---
-DEFNRVDLMLVIGTSRAVWPAASYVDIVN---GKIAIFNTEPDGDE-KDCWQFIGDSAETLPVAMEPL----------
>tr|C0S043|C0S043_PARBP Uncharacterized protein OS=Paracoccidioides brasiliensis (strain Pb03) GN=PABG_01801 PE=4 SV=1
--------------------------------------GSKNVMALLGAGLSAS-GLPTFRG-GGLWRSHYVTSLATPEAFQSKPALVWQFYSYRRHM--
ALKAQPNKAHFALAALAKR-NPNFITLSQNVDGLSP-RNHSQLHLLHGSLFQVKCSSCKYVA-EDDPIVSLPKCPKCKN-QLLRPGVVWFGESLQTI---
-DDWDKIDLILVIGTSAQVFPAAGYVEMAE---ARVAVINMDTNDEPPPGDWFFQGDASVIVPELLRDA----------
>tr|C6HDD9|C6HDD9_AJECH Transcriptional regulatory protein OS=Ajellomyces capsulatus (strain H143) GN=HCDG_04220 PE=4 SV=1
--------------------------------------GSKNVMALLGAGLSAS-GLPTFRG-GGVWRSYPATSLATPEAFEANPGFVWQFYSYRRHM--
ALKANPNRAHFALAELARK-NPHFITLTQNIDGLSS-RRHSQLHLLHGSLFDVKCASCTYAT-QDDPIVSLPQCPLCKE-NILRPGVVWFGEALKTV---
-QKWDRIDLILVIGTTAQVFPAAGYVEDAD---ARVAVVNMDIEDIPPPGDWFFQGDASVVVPELLRDV----------
>tr|F2T266|F2T266_AJEDA SIR2 family histone deacetylase OS=Ajellomyces dermatitidis (strain ATCC 18188 / CBS 674.68) GN=BDDG_00487 PE=4 SV=1
--------------------------------------NSRNVVALLGAGLSAS-GLPTFRG-GGVWRSYPASSLATPGAFKANPGFVWQFYSYRRHM--
ALKAKPNRAHFALAELARR-NPNFITLTQNVDGLST-RNHSQLHVLHGSLFDVKCASCDYSR-EDDPIVSLPQCPQCKN-NILRPDVVWFGESLKTL---
-DKWDTIDLMLVIGTTAQVFPAAGYVEMAE---ARVAVINMDSSDTPPPGDWFFQGDASMIVPELFKDV----------
>tr|A0A0C3CQE3|A0A0C3CQE3_9PEZI Uncharacterized protein OS=Oidiodendron maius Zn GN=OIDMADRAFT_123652 PE=4 SV=1
---------------------------------------SKRILALCGAGLSAS-GLDTFRG-GGMWKNYDAMELATPEAFSRDPGLVWLFYSYRRHK--
ALRASPNPGHYALTELSKI--PGFITLTQNVDGLHQ-RNHEQLKLLHGSLFDIKCF-CNYLQQNNDPFHALPHCPTCTT-GLLRPGVVWFNEMLNTL---
-DSF-PIDLIMVIGTTAKVYPAAGYVSQAG---AKVALINTEADDLG-KDDFLFQGDSAKILPEILKPV----------
>tr|A7EAF6|A7EAF6_SCLS1 Putative uncharacterized protein OS=Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1) GN=SS1G_02288 PE=4 SV=1
---------------------------------------SKRVLALCGAGLGAS-GLDTFRG-GGLWRNYRAENLATMDAFTRDPGLVWLFYSYRRHK--
ALAAEPNKGHFALAELARRDEEGFVCLTQNVDGLAQ-RGHGSLKLLHGCLYDIKCADCDYRERNNDPFHLLPHCPKCTT-ALLRPDIVWFGEPLDTL---
-DRW-PVDLILVIGTTAKVYPAAGYVDVAD---AKVAVINMDAEGLG-KNDWLFLGDAGTILNEILSPL----------
>tr|W9CM58|W9CM58_9HELO Uncharacterized protein OS=Sclerotinia borealis F-4157 GN=SBOR_4011 PE=4 SV=1
---------------------------------------STRVLALCGAGLGAS-GLDTFRG-GGMWRNHRAQSLATLDAFTRDPGLVWLFYSYRRHK--
ALAAEPNKGHFALAELAKREEEGFVCLTQNVDGLAQ-RDHGSLKLLHGCLYDIKCANCDYRERNNDPYHLLPHCPQCPN-SLLRPDIVWFGETLHTL---
-DRW-PVDLILVIGTTAQVYPAAGYVDVAN---ARVAVINMDAQGLG-MDDWLFLGDAGEILEEILSPP----------
>tr|A0A010SJ77|A0A010SJ77_9PEZI NAD-dependent deacetylase sirtuin-5 OS=Colletotrichum fioriniae PJ7 GN=CFIO01_02414 PE=4 SV=1
--------------------------------------KSKRIVAVIGAGLSVS-GLATFRG-NGLWRNQDITQVASPAGFRHDPGLVWQFYTYRRHD--
ALRAKPNPAHYALAELARR--PGFVALTQNVDNLSP-RGHSQLKELHGNLFALSCVDCGYSERDNESLSILPQCPKCKN-SILRPAVVWFGEPLEVV---
-QALEPIDLFLTIGTTSKVWPAAGYAEMAK---ARVAVINTRAED-ARDKDWVFVGDAAVVLPQLLKPV----------
>tr|T0KZ34|T0KZ34_COLGC NAD-dependent deacetylase sirtuin-5 OS=Colletotrichum gloeosporioides (strain Cg-14) GN=CGLO_01959 PE=4 SV=1
--------------------------------------QSKRIVAIVGAGLSAS-GLATFRQ-SGPWTNQDMTQVASPAGFRHDPGMVWQFYTYRRQE--
ALRAKPNPAHYALAELARR--PGFVTLTQNVDNLSQ-LGHDQMKELHGNLFTLSCFDCGYVERDNTSLTVLPQCPKCKT-NLLRPGVVWFGEPLELV---
-EAVAPIDLCLVIGTSSSVWPAAGYAEMAK---ARVAVINIHADD-AKNQDWVFVGDAAVVLPELLKPV----------
>tr|C7YXF3|C7YXF3_NECH7 Putative uncharacterized protein SRT2101 OS=Nectria haematococca (strain 77-13-4 / ATCC MYA-4622 / FGSC 9596 / MPVI) GN=SRT2101
--------------------------------------KSKRIIAVIGAGLSAS-GLAVFRG-SGLWKSQDVTQVASPAGFRHDPGLVWQFYSYRRQE--
ALGAKPNPAHYALAELARQ--PGFVALTQNVDNLSP-RGHGQMKELHGNLFTLSCIDCGYVERDNECLTVLPQCPKCKA-NILRPDVVWFGEPLQVV---
-EALEPIDLCLNIGTSNRVWPAAGYAAMAD---ARVAYINTRAED-AKGRDWIFVSDAAVVLPELLKPI----------
>tr|A0A0C7MUE9|A0A0C7MUE9_9SACH LALA0S08e03730g1_1 OS=Lachancea lanzarotensis GN=LALA0_S08e03730g PE=4 SV=1
--------------------------------------HAKKVLCIVGAGMSAS-GIPTYQW-KGSWRGYTALDLATPEAFQNNPGLVWLFYSSRRLE--
ALRARPNDAHFALAELCRRTSRRVLVVSQNMDGLHQ-RGHDSLVELHGSVFGLKCTQCNYRSCNDRFLTSLPRCPECHE-GLLRPAVVWFGESLHQM---
-DQFGPVDLVLVIGSSGKVWPAMGYVERAK---SKIAIFNTTIEDLEEKNVWGFQGDAAKILPKALKPL----------
>tr|M9N0L0|M9N0L0_ASHG1 FABL004Wp OS=Ashbya gossypii (strain FDAG1) GN=FAGOS_FABL004W PE=4 SV=1
--------------------------------------GARKILCIVGAGLSAS-GLTTFQA-HGEWRGHSALELATPEAFQENPELVWVFYSARRYT--
AMKARPNNGHFALAELCRRERREILLVTQNVDGLHW-RGQASTVELHGSVFDYRCTECSYRGRNVHFLT-LPRCPRCRV-GLLRPGVVWCGESLVQM---
-DAFQKVDLVLVIGTSGRLWPAMGYVERAL---SRIAFFNTDIEDAAGKRMWAFQGNAAELLPQALEPV----------
>tr|S6EZH8|S6EZH8_ZYGB2 BN860_15720g1_1 OS=Zygosaccharomyces bailii (strain CLIB 213 / ATCC 58445 / CBS 680 / CCRC 21525 / NBRC 1098 / NCYC 1416 / NRRL
--------------------------------------QARKILCVVGSGLSQS-GIPTYQL-RGTWKGYTSLDLATPEAFQSNPGLVWLFYSNRRYI--
AMKAKPNDGHFALARLAKNRHREVFVVTQNVDGLHQ-RGQEDLCELHGSLFQLRCTSCTYKGKNTLFLTSLPHCPKCGE-GLLRPGVVWFGEPLMEM---
-DKFDHIDLVLVIGTGGKVWPAMGYVERCQ---GRVAIFNTHIEDKEKKTLWGFEGEAAVWLPRALEPL----------
>tr|G8ZUX7|G8ZUX7_TORDC Uncharacterized protein OS=Torulaspora delbrueckii (strain ATCC 10662 / CBS 1146 / NBRC 0425 / NCYC 2629 / NRRL Y-866) GN=TDEL0
--------------------------------------QAERVLCIVGAGLSQS-GIPTYQL-RGSWKGYTSLDLATPEAFQANPGLVWLFYSNRRYI--
AMRAKPNRGHYALAELSRRRNRNALVVTQNVDGLHR-RDQEKLCELHGSLFDLRCTSCTFKGSNTLFLTSLPHCPKCHE-GLLRPGVVWFGEPLLQM---
-DTFSHSDLVLVIGTSGKVWPAMGYVERCQ---GRIAIFNTKIDDKDAKSCWAFEGEAAYWLPRALEPI----------
>tr|C5DRF3|C5DRF3_ZYGRC ZYRO0B08008p OS=Zygosaccharomyces rouxii (strain ATCC 2623 / CBS 732 / NBRC 1130 / NCYC 568 / NRRL Y-229) GN=ZYRO0B08008g PE=4 
--------------------------------------QCRKILCVVGAGLSQS-GIPTYQL-RGTWKGYTSIDLATPEAFQTNPGLVWLFYSNRRYI--
AMKARPNEGHFALAELAKRRRREAFVVTQNVDGLHQ-RGQADLCELHGSLFQLRCTSCTYKGKNTLFLTSLPHCPVCHE-GLLRPGIVWFGEPLMDM---
-DEFDHIDLVLVIGTSGKVWPAMGYVERCQ---GRVAIFNTHIEDKDKRTVWGFEGEASEWLPRALEPF----------
>tr|C5DBK2|C5DBK2_LACTC KLTH0A03300p OS=Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284) GN=KLTH0A03300g PE=4 SV=1
--------------------------------------KARKILCIVGSGVSAS-GIATYQL-KGSWHGYTALDLATPEAFQNDPGLVWLFYSNRRYE--
ALRAKPNEGHYALAELCRRDKKKVLVVSQNVDGLHQ-RGHESLVELHGSVFGLRCTQCNYRSRNSRFLTSLPSCPQCHQ-GILRPAVVWYGESLDQM---
-DQFGPVDLVLVIGTSGKVWPAMGYVERAK---SRVAIFNRVIEDLDQKDIWGFQGDAAQLLPKALKPL----------
>tr|A0A061AUE6|A0A061AUE6_CYBFA CYFA0S05e04720g1_1 OS=Cyberlindnera fabianii GN=CYFA0S_05e04720g PE=4 SV=1
--------------------------------------RSRTILAVVGAGLSAS-GLPTFRG-GGLWRNYASIDLATPEAFLADPGLVWQFYSSRRYQ--
ALKVRPNKGHFALAELGRRNGKKFMMLTQNVDGLDI-RGHKTCLELHGSLFTLKCTSCTYVEKGNHPLVSLPHCPRCKS-GLLRPGVVWFGESLDVI---
-DQFNEVDLCLVIGTSGTVWPAMGYVERVG---GKVAVFNMDEKDIEMRGGWGFAGDAAEWLPLALEPL----------
>tr|F2QQR9|F2QQR9_PICP7 Sirtuin OS=Komagataella pastoris (strain ATCC 76273 / CBS 7435 / CECT 11047 / NRRL Y-11430 / Wegner 21-1) GN=SIR1 PE=3 SV=1
--------------------------------------KCRTILALCGAGLSAS-GLPTFRG-GGLWKNYSSMDLATPDAFNVDPGLVWQFYSYRRYK--
AIQAKPNNGHYALSQLSKVKGKKFLTLTQNVDGLSR-RHHEQLLELHGSLFTLKCTSCTYTENNNHPLTSLPTCPQCKT-GLLRPGVVWFGESLKVL---
-DQFQKVDLILVIGTSQSVWPAAGYVNRVL---GKVAIFNTDEEDLE-CDGWKFLGDAAELLPQALKPL----------
>tr|A0A0H5BYC5|A0A0H5BYC5_CYBJA Uncharacterized protein OS=Cyberlindnera jadinii GN=BN1211_0188 PE=4 SV=1
--------------------------------------SCKTILAVVGAGLSAS-GLQTFRG-GGLWRNYSPIDLATPDAFHVDPGLVWQFYSSRRFL--
ALKARPNKGHFALAELSRR-DVNFLTLTQNVDGLST-RRQDTLLELHGSLFTLRCTGCNYVEENNHPLTSLPHCPKCN--SLLRPGVVWFGESLKVI---
-DEFNHVDLVLVIGTSGTVWPAMGYVERVQ---GKIAVFNTEIDEED-HGGWGFKGDAAEWLPKALEPL----------
>tr|K0KK02|K0KK02_WICCF NAD-dependent deacetylase OS=Wickerhamomyces ciferrii (strain F-60-10 / ATCC 14091 / CBS 111 / JCM 3599 / NBRC 0793 / NRRL Y-10
--------------------------------------QANNILAVVGAGLSAS-GLSTFRG-GGLWRNFSAIDLATPDAFHFDPGLVWQFYSARRFN--
ALKAKPNKGHYALAELSNR-GGNFLTLTQNVDGLST-RGHDHLLELHGSLFTLKCTNCNYVDKYNHPLTSLPHCPECKE-GLLRPGVVWFGESLKAV---
-DEFNKVDLVLVIGTSGNVWPAMGYVERVK---GKVAVFNTEIDNIDQEHNWGFIGDASKWLPLALEPI----------
>tr|S3D3K3|S3D3K3_GLAL2 DHS-like NAD/FAD-binding protein OS=Glarea lozoyensis (strain ATCC 20868 / MF5171) GN=GLAREA_02559 PE=4 SV=1
---------------------------------------SKRILALCGAGLSAS-GLDTFRG-GGMWRNYRATSLATPEAFENDPGLVWLFYALRRHQ--
ALNAKPNMAHFALAELARQGEEGFQCLSQNVDGLSQ-RSHSQLKLLHSTLFNLKCFNCTYLDIDNDPLCLLPHCPSCET-GLLRPGVVWFGEALETI---
-DEWESVDLILVIGTTATVWPASSYVEIAR---AKVAVVNMDDGELG-EGDFWFQGDAAVLVPQMLEPV----------
>tr|W2RUH0|W2RUH0_9EURO Uncharacterized protein OS=Cyphellophora europaea CBS 101466 GN=HMPREF1541_06172 PE=4 SV=1
--------------------------------------KSKRIVALLGAGLSAS-GLPTFRG-GGYWRTYDATMLASPNAFRNDPGLVWQFYSYRRHM--
ALNAKPNRAHLALAELARR-NPDFITLSQNVDNLSP-RGHSQLKLLHGNLYDVKCWDCSYIRKNDDPIVSLPQCPQCKK-NLLRPGVVWFGESLDVM---
-DVFRPIDLMLVIGTSSKVYPAAGYSHIAR---ARLAVINMDEGDA--RDDWFFEGDAAVIVPEILSSV----------
>tr|A5DW75|A5DW75_LODEL Putative uncharacterized protein OS=Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-42
--------------------------------------KCKKIVALVGAGLLAS-GLPVFRGSQGLWKNYNMIDLATPDAFYVDPGLVWQFYSWRRYA--
ALQAKPNRGHLALAKLSKLPSFKFVTITQNVDGLSS-RE-QSLYEIHGSLFTLKCTSCNYVEKNNQPLTSLPRCPVCSE--LLRPGVVWFGESLDVI---
-DNF-PVDLILVIGTSGTVYPANSYVERVY---GKVAIFNTDIDSRV-KDSWGFKGDAAELLPLALEPL----------
>tr|H8X1S7|H8X1S7_CANO9 Uncharacterized protein OS=Candida orthopsilosis (strain 90-125) GN=CORT_0B07770 PE=3 SV=1
--------------------------------------KSKKIIALVGAGLSAS-GLPVFRGSQGLWKNYNMIDLATPDAFYIDPGLVWQFYSWRRFS--
ALRAEPNDGHIALAKLSHMSNLKYLTISQNVDGLSN-RRRKKLYEIHGSLFTLKCTSCNHVEKNNQPLTSLPRCPVCDG--LMRPGVVWFGESLDLI---
-DSF-APDLILVIGTSGTVYPANSYVERVL---GRVAIFNMDIEDDV-DGTWGFKGDAAKLLPVALEPL----------
>tr|A0A0H1BQW9|A0A0H1BQW9_9EURO Uncharacterized protein OS=Emmonsia parva UAMH 139 GN=EMPG_11343 PE=4 SV=1
--------------------------------------SSKRILTLLGAGLSAS-GIGTYVDEGGFWRTN-VRRLCTYGAFREDPSLIWWFYSDRRRE--
AMKAEPNKAHHALAKLA-R-MLTVCFNNHNNVGLCP-RGQTSTVYLHGDYFTIKCSSCTYSRA-DDPIVSLPRC------SLLRPGVTWFGETMAQV---
-HDWGQIDLVLVIGTAATVHPVLSLVTQA--R-AKVCVVNPDQESAQKEGNWWFRGGAAEVLPEIFKEV----------
>tr|A0A0N1P4E4|A0A0N1P4E4_9EURO NAD-dependent protein deacylase OS=Phialophora attae GN=AB675_851 PE=4 SV=1
--------------------------------------NSRRIVALLGAGLSAS-GLPTFRG-GGLWRNYDATVLATPTAFRNDPGLVWQFYSYRRHM--
ALNAKPNPAHYALAELARR-NPQFLTLSQNVDNLGP-RGHKQLKLLHGNLFDIKCWDCGYVRKNDDPIVSLPHCPKCEK-NLLRPGVVWFGESLDVM---
-NDYDKIDLMLVIGTSAKVWPAAGYSAMAK---ARVAVINMDRSDA--SDDFFFEGDAAVLVPQLLEGV----------
>tr|U1GSX5|U1GSX5_ENDPU Uncharacterized protein OS=Endocarpon pusillum (strain Z07020 / HMAS-L-300199) GN=EPUS_08327 PE=4 SV=1
--------------------------------------RSQRIVAVPGAGLSAS-GLPTFRG-GGLWRNYNATSLATPGAFRSDPGLVWMFYSYRRHM--
SLNAKPNPAHYALAELARR-KPEFLTLSQNVDGLSP-RGHDQVKLLHGSLFDVKCEDCGYIRRDDDPIVSLPHCPKCKT-SLLRPGVVWFGEMLAVL---
-DAYKKVDLCLVIGTSSQVYPAAGYASQAS---ARVAVINTDPSDA--EGDWFFKGDAADIVPEILKSV----------
>tr|A0A084ARR3|A0A084ARR3_STACH Uncharacterized protein OS=Stachybotrys chartarum IBT 7711 GN=S7711_09322 PE=4 SV=1
--------------------------------------QSKRIVALLGAGLSAS-GVPTFATFQGPWRNYVADQFSTPAAFRHDPGLVWQYYSHMRHQ--
ALMADPNPAHYALAELARQ--PGFITLTQNIDNLSQ-MGHHQLRELHGNIFNLRCFDCGYKEKSNDPITLLPRCPKCSS-NLLRPDIVWFGEPLGLV---
-NAIQPIDLCLVIGTSSTVWPAAGFPELAR---ARIAVVNIDTGN-VKGIDWVFECDASIAVPELLRPL----------
>tr|M7T5B7|M7T5B7_EUTLA Putative sir2 family histone deacetylase protein OS=Eutypa lata (strain UCR-EL1) GN=UCREL1_1133 PE=4 SV=1
--------------------------------------GARRTIAVLGAGLSAS-GIPTYRSRSALWRNHDIAAVATPAALRRDPGLVWEFYASRRRQ--
ALGADPNAAHWALAELARRGEKTFLALTQNIDGLSI-RGHDGIWNLHGSLFDLKCTDCGYRERDNEPLTVLPRCPKCKT-NLLRPDVVWFGETLDVV---
-DAL-GVDLCLVVGTSSTVWPVAGYADRAA---ARVAVVNTDPGD-AKG-DWVFVGGAAEVLPVLLEPV----------
>tr|A0A0L0HKL8|A0A0L0HKL8_SPIPN Uncharacterized protein OS=Spizellomyces punctatus DAOM BR117 GN=SPPG_09117 PE=4 SV=1
------------------------------------------MLVGIGAGVSTSAGISDYRSSNGLFA--AVKQGFDAHSFRQNARAFYQIAHHHARACL
APSCRPTPFHQVLGKWCH-AGHIRRVYSQNIDVLDEAVGI-KLVKMHGDLHRLRCPLCETQYALPDEFWSLPTCPGRV--PAVLPAVVRYGEAVEIATNM
QGDLLHIDGLLIAGTRMAIPGFRDFAKAASAVLFLAIYVNREPCQTNMYFDFQFVGDADEFALRVQDFL----------
>tr|A0A0D1X8J8|A0A0D1X8J8_9PEZI Uncharacterized protein OS=Verruconis gallopava GN=PV09_09821 PE=4 SV=1
------------------------------------LIASTRVLYVVGTELSAASGLAT-------WR--------------DDPVIVWRFYGERLLKSL
--ASQPNAAHHALAALATWH-PGWLTINQNVDGLLEQTAHPMLLGIHGSLTAVRCTVCKYVVRTPHGVSHLPRCPECG--NLLRPGVVWFGERAAGPDSV
DEWMSPVDLVIAIGTSLEVYPAAEWVSTARAEGASLLVIDIDKDNKLARNDWIFKGDAAIIMPEMFWSVERTGKR----
>tr|A0A016XFU2|A0A016XFU2_9BURK NAD-dependent protein deacylase OS=Hylemonella gracilis str. Niagara R GN=AZ34_02400 PE=4 SV=1
------------------------------------TPRKPSLVVFTGAGISAESGLATFRDANGLWNSHRPEELASIQAWRRDPALVLEFYNQRWKQLQ
--TVKPNSAHYAIAELEQAY--DVTVITQNVDDLHERAGSTKIVHLHGELMKVC-EQATY------KVEDLG--PT--G-RQLRPFIVWFGEDPLIVAQ-
--EIVKADVFIVVGTSLNVYPAASLVDDARRASPKFL-VNKEHSLGTLGEDWTVLGPATVGMSEVKHSLLTKRGK----
>tr|A0A066XWE9|A0A066XWE9_COLSU Putative Sir2 family protein OS=Colletotrichum sublineola GN=CSUB01_02380 PE=4 SV=1
------------------------------------LRSGKRILALCGAGLSASSGLPTFRGAGGLWRNHDATALATMDAFRRDPGLVWLFYAYRRHMAL
--NAQPNPAHYALAALAEK-NPDFLCLTQNVD-LSPRVGHKSLRRLHGSLFDIKCANCAYVDNTLDDDTHLPHCPSCKT-GLLRPGVVWFGEGDEALDGI
NAWISKVDLMLVIGTSAQVWPAAGYILEAQKAGARVCIINPEAEGKG-RGDFAFGRDAAEVLPLLLEPVIGKIPT----
>tr|A0A084G6M2|A0A084G6M2_9PEZI Putative SIR2 family histone deacetylase OS=Scedosporium apiospermum GN=SAPIO_CDS5436 PE=4 SV=1
------------------------------------LTENPRILLVCGAGLSASSGLPTFRGAGGLWRNHSATALATPMAFQRDPGLVWLFYAYRRHMCM
--NAVPNRGHLALAALAEKY-SNVFCVSQNVDNLLEKANYPRLRKIHGCLFGLKCSDCTWRSYTDDPAKDIPKCPQCQNRALQRPDIVWFGESDDRVDDI
QNWID-VDVVLSIGTSEAVSTAAGFLYDARAQGAVYV--NVNLDAEEEDEDFAFGGDASELLPKLFGPIIGEI------
>tr|N4V9Q3|N4V9Q3_COLOR Sir2 family histone OS=Colletotrichum orbiculare (strain 104-T / ATCC 96160 / CBS 514.97 / LARS 414 / MAFF 240422) GN=Cob_07745
------------------------------------LGSSKRILALCGAGLSASSGLPTFRGAGGLWRNHDATSLATHRAFHRDPGLVWLFYAYRRHMAL
--NAKPNPAHYALAALAEK-NPDFLCLTQNVD-LSPKAGHKELHKLHGSLFDVKCY-CAYIENTADPAEDLPHCPSCES-GLLRPGVVWFGEGDLTLREI
DAWISKIDLMLVIGTSAQVYPAAGYISTAHEAGARICTVNPEAENED-QGDFAFGRDAAEVLPLLLEPVIGKLGE----
>tr|H1VDY8|H1VDY8_COLHI Sir2 family protein OS=Colletotrichum higginsianum (strain IMI 349063) GN=CH063_09532 PE=4 SV=1
------------------------------------LRSSKRILALCGAGLSASSGLPTFRGAGGLWRNHDATALATMAAFRKDPALVWLFYAYRRHMAL
--NARPNPAHYALAALAEK-NPDFVCLTQNVD-LSPRAGHKTLRRLHGSLFDIKCANCDYIDNTLDDVVDLPHCPSCKK-SLLRPGVVWFGESDKELDGV
NAWINKVDLMIVVGTSAQVWPAAGYILEAHKAGARVCTVNPEAEDRD-QGDFAFGRDAAEALPLLLEPVIGKLRA----
>tr|A0A010RB96|A0A010RB96_9PEZI Sir2 family protein OS=Colletotrichum fioriniae PJ7 GN=CFIO01_05138 PE=4 SV=1
------------------------------------LASSKRILALCGAGLSASSGLPTFRGAGGLWRNHDATDLATMKAFRRDPGLVWLFYAYRRHMAL
--SAKPNKAHYALAALAEK-NPDFLCLTQNVD-LSPRAGHKELRLLHGSLFDIKCANCTYIDNTQDDEADLPHCPSCKT-GLLRPGVVWFGEADDALDGV
DAWIEKVDLMIVVGTSAQVWPAAGYILKAHAAGARVCTVNPEAEDEG-QGDFAFGRDAAEVLPLLLEPVIGKMRA----
>tr|E3QRN9|E3QRN9_COLGM Sir2 family protein OS=Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212) GN=GLRG_08806 PE=4 SV=1
------------------------------------LRSSKRILALCGAGLSASSGLPTFRGAGGLWRNHDATALATMDAFSRDPGLVWLFYAYRRHMAL
--NAQPNPAHYALAALAEK-NPDFLCLTQNVDGLSPRAGHKTLRRLHGSLFDIKCANCTYVDNTLDDDADLPHCPSCKT-GLLRPGVVWFNESDGALNGI
DEWIRSVDLMLVIGTSAKVYPAAGYILEARKAGARVCTINPEAEVESQRGDFAFARDAAEVLPLLLEPVIGKMPT----
>tr|M7T3C5|M7T3C5_EUTLA Putative sir2 family histone protein OS=Eutypa lata (strain UCR-EL1) GN=UCREL1_1573 PE=4 SV=1
------------------------------------VRSGARILALCGAGLSAASGLPTFRGAGGLWRNHEPTSLATPEAFAVDPGLVWLFYAWRRHMAL
--KANPNRAHYALAELAKWK-KGFMCLSQNVDGLSPRAGHPALRLLHGSILDIKCFDCGYIDNLSDKPEDLPHCPSCKT-GLLRPGVVWFGEPDELLMEV
ENWIMRIDLMIVIGTAAAVYPAAGYTRKARRRGARVAVVNPDPDAAG--ADFFFQGDAAEILPQLFEGVIGKMDE----
>tr|L2G6P5|L2G6P5_COLGN Sir2 family histone OS=Colletotrichum gloeosporioides (strain Nara gc5) GN=CGGC5_5886 PE=4 SV=1
------------------------------------LKSSKRILALCGAGLSASSGLPTFRGAGGLWRNHDATSLATMNAFRNDPGLVWLFYAYRRHMAL
--TVKPNPAHYALAALAEK-NPDFLCLTQNVD-LSPRAGHNVLRRLHGSLFDIKCA-CDYVENTADEDADLPHCPSCKE-GLLRPGVVWFGESDAGLDGV
EAWIEKVDLMLVIGTSAQVWPAAGYILKAHKAGARVCTVNPEAEDKN-QGDFAFGRDAAEVLPLLLEPVIGKIDE----
>tr|A0A0B0E572|A0A0B0E572_NEUCS DHS-like NAD/FAD-binding domain-containing protein OS=Neurospora crassa GN=GE21DRAFT_1043350 PE=4 SV=1
------------------------------------LAKADRILAICGAGLSAASGLPTFRGVGGLWRNYEATDLATPEAFASDPGLVWLFYAYRRHMAL
--QALPNAGHHALAALAKKN-PNFLCLTQNVDNLSSRAGHQQLHTLHGSLFTLQCSSCTYIDNTLDPKSHLPHCPQCK--NLLRPGVVWFGESNPGLAEI
DAWIDPIDIVLVIGTSSVVYPAAGYAEKARTKGKTSVTVNMEVGVEVDDEDLVFQGGAEEWLPRMLEPVIGVAKD----
>tr|B2ARI4|B2ARI4_PODAN Podospora anserina S mat+ genomic DNA chromosome 4, supercontig 4 (Fragment) OS=Podospora anserina (strain S / ATCC MYA-4624 / 
------------------------------------LLKSNRILAVCGAGLSAASGLPTFRGAGGLWRNHNAVDLATPEAFDADPGLVWLFYAYRRHMAL
--TAKPNPAHYALAELARK-RPGFKCLSQNVD-LHVRANHPSLSLLHGSLFTLKCT-CSWKDNIADKESELPHCPDCKT-ELQRPGVVWFGEMDEDLDDI
EEWIEPVDMVLVVGTSSAVYPAAGYAERARTKG-RVVTVNLEI-TEE-DGDFGFEGDASLLLPELLRPVIGEVKG----
>tr|I1S9M1|I1S9M1_GIBZE Uncharacterized protein OS=Gibberella zeae (strain PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084) GN=FGSG_13552 PE=4 SV=1
------------------------------------LRSSKRILALCGAGLSASSGLPTFRGAGGLWRNHDATSLATLRAFNDDPGLVWMFYGYRRHMAL
--RAQPNPAHYALAKLAEK-NEDFLCLTQNVD-ISPRANHPPLRTLHGSLFDIKCNNCSWIENYKDPRDEIPKCPECKT-GLQRPAVVWFGENDEDITGI
TSWLWKVDLMLVIGTSAKVYPAAGFIEKARHRGARIAVINPEAENEE-EGDFAFGQDAAEYLPILLEPVIGKLGK----
>tr|A0A086T430|A0A086T430_ACRCH NAD-dependent protein deacylase-like protein OS=Acremonium chrysogenum ATCC 11550 GN=ACRE_050840 PE=4 SV=1
------------------------------------LRTSRRVLALCGAGLSVSSGLPTFRGAGGLWRSYPSQELATFRAFRTNPGLVWLFYGYRRHLAL
--KAKPNDGHRALAALARTKGSEFLCLTQNVD-LSQRANHPPLLALHGSLFDIKCV-CDWIQNFDDTEDELPKCPECKT-NLQRPGVVWYGEDDPSLATA
DQFLAPIDMILVVGTSAQVWPAAGYIEKARRRGARVVVVDMNAEDPE-EDDFAFARDAAKALPVLLEPLIGKLQG----
>tr|A0A0B7K1J8|A0A0B7K1J8_BIOOC Uncharacterized protein OS=Bionectria ochroleuca GN=BN869_000005489_1 PE=4 SV=1
------------------------------------LLSSRRIIALCGAGLSAPSGLETYRGPGGLWKKYDVNKLSTATAFRDDPSFVWLLYANRRHTAL
--KAEPNNAHRALAALALE-RPEFLCMTQNVD-LSRRANHPLLLTLHGSLFNLKCT-CDWVQNFDDEKKDLPKCPQCPL-GLQRPDVVWFGEKDINVRRA
DNFVDPLDMMLVIGTSALVWPAAGYIGRARGQGARIVTIDLTAEDPE-QGDLMFAGDASELLPLLLEPVIGKMQT----
>tr|A0A063BZ20|A0A063BZ20_9HYPO NAD-dependent deacetylase sirtuin-5 OS=Ustilaginoidea virens GN=UV8b_3797 PE=4 SV=1
------------------------------------LRSSRRILALCGAGLSASSGLPTFRGAGGYWRSHDAAKLATMRAFMTDPGLVWLFYGYRRHLAL
--QAKPNAGHRALAALANK-SSNVLCLTQNVD-EFDHLGRRAREIPLSLGFTLSSYR--PHNSDPDTEEELPRCPKCKT-GLQRPGVVWFGEEDKALERI
NDWIARVDLMLVVGTSAQVYPAAGFISRAKLHGARIVNINPEAEDEA-EGDFAFGQDAAKCLPRLLEPVIGKLSD----
>tr|A0A0E9KZI8|A0A0E9KZI8_9HYPO Uncharacterized protein OS=Ustilaginoidea virens GN=UVI_057410 PE=4 SV=1
------------------------------------LRSSRRILALCGAGLSASSGLPTFRGAGGYWRSHDAAKLATMRAFMTDPGLVWLFYGYRRHLAL
--QAKPNAGHRALAALANK-SSNVLCLTQNVD-LSQRAGHPPLCTLHGSLFDIKCTTCGWIQNFDDTEEELPRCPKCKT-GLQRPGVVWFGEEDKALERI
NDWIARVDLMLVVGTSAQVYPAAGFISRAKLHGARIVNINPEAEDEA-EGDFAFGQDAAKCLPRLLEPVIGKLSD----
>tr|G2QRA2|G2QRA2_THITE SIR2 family histone deacetylase-like protein (Fragment) OS=Thielavia terrestris (strain ATCC 38088 / NRRL 8126) GN=THITE_14941 
------------------------------------LARSRRILAVCGAGLSAASGLPTFRGAGGLWRNYDATELATPEAFEADPGLVWMFYAYRRHMAL
--QAKPNPGHYALAALARK-NPDFLCLTQNVD-LHSRAGHPPLHLLHGSLFTIKCDSCSWTDNFDDPPSDLPHCPQCRT-GLQRPGVVWFGEPSRPLDAV
NAWIAAVDVVLVIGTSSVVYPAAGFAEAARAPGGRVVTVNLE-IGPG-VEDFAFEGDAAVLLPKLLAPVIGDLEG----
>tr|D5GFR3|D5GFR3_TUBMM Uncharacterized protein OS=Tuber melanosporum (strain Mel28) GN=GSTUM_00007018001 PE=4 SV=1
-------------------------------------------MALCGAGLSAASGLPTFRGAGGTWRNYEATMLATPEAFEADPGLVWQFYSMRRHMAL
--AAKPNAAHFALAELARRKGGGFRTLTQNVDGLSARANHPPIDYLHGHLFGVKCFSCDYRVDFRDPRERIPKCPKCN--NLLRPGVVWFGEVDEDLVSI
DRWID-VDSCIVIGTSGNVNPAADYAYKVRECGGKVAIVDLDVSAGGWRFDWVFEGDASKIVPELLRPLIGDITI----
>tr|K1VJU0|K1VJU0_TRIAC Uncharacterized protein OS=Trichosporon asahii var. asahii (strain CBS 8904) GN=A1Q2_01304 PE=4 SV=1
-------------------------------------LRHPRILAVCGAGLSASSGLPTFRGAGGLWRNYEATSLATPQAFKRDPGLVWTFYAYRRHRAL
--GVQPNGGHWALARLAERLGDDFLCLTQNVDKLHERAQHPALKHLHGSLFQLKCTLCPWKAD-RDSAQDLPRCPECG--GLARPAVVWFGESDADLQQA
DEWIEPVDIVLVVGTSAVVYPAAGYAELARTRNTHVVTINLEIEGGRRNNDFHFEGDASVLLPQLLEPIIGKPSE----
>tr|A0A0P7B7N7|A0A0P7B7N7_9HYPO Uncharacterized protein OS=Neonectria ditissima GN=AK830_g3987 PE=4 SV=1
------------------------------------LRSSKRILALCGAGLSASSGLPTFRGAGGLWRNHEATQLATMNAFRTDPGLVWLFYGYRRHMAL
--RADPNPAHHALAALARQ-NEDFLCLTQNVD-LSQRADHPPLRTLHGSLFDIKCANCDWIQNYDDTEEEIPKCPECGT-GLQRPGVVWFGESDADLAGV
DTWMFKLDMMFVIGTSAKVWPAAGFISRAKRLGATIVTVNPDAENEE-EGDFAFGQDAAEYLPLLLEPVIGKLPE----
>tr|A0A0J0XRV2|A0A0J0XRV2_9TREE DHS-like NAD/FAD-binding domain-containing protein OS=Trichosporon oleaginosus GN=CC85DRAFT_307447 PE=4 SV=1
------------------------------------LGRAKRILAICGAGLSASSGLPTFRGAGGLWRNYESTSLATPQAFARDPGLVWLFYGYRRHVAL
--GVSPNDGHRALAKLAER-QPGFLCLTQNVD-LHERAGHSVLRHLHGSLFDLKCSNCDWVENQDDPESELPHCPRCKK-GLQRPGVVWFGEQDHALAEV
DAWIDSVDIVLVVGTSSVVYPAAGYAERARSAGTSVVTVNLDADID---GDFAFAGDAAKLLPELLEPVIGKL------
>tr|A0A084Q8N0|A0A084Q8N0_9HYPO Uncharacterized protein OS=Stachybotrys chlorohalonata IBT 40285 GN=S40285_08225 PE=4 SV=1
------------------------------------LRSSRRIMALCGAGLSASSGLPTFRGAGGLWRNHDAKSLATPGAFARDPGLVWLFYGYRRHMAL
--RARPNAAHRALAALARVKGEGFLCLTQNVD-LSPRAGHPPLRLLHGSLFDIKCSNCDWTQNYEDPASQLPHCPACGT-GLQRPGVVWFGEGDGALAGV
DAWMDGVDLMLVVGTSATVYPAAAYIDEARARGARVVNVNPEAEDRR-EGDFAFGQDAAAYLPILLKPLIGEVPA----
>tr|G3JDG0|G3JDG0_CORMM SIR2 family histone deacetylase, putative OS=Cordyceps militaris (strain CM01) GN=CCM_04008 PE=4 SV=1
------------------------------------LLSSRRILILCGAGLSASSGLPTFRGAGGYWRHHDATRLATMQAFRTDPGLVWLFYGYRRHTSL
--QAQPNAGHRALAALAKA-NPDVLCLSQNVD-LSQRAGYPLLHTLHGSLFNIKCSNCDWMQNYDDPEEELPKCPQCNT-GLQRPGVVWFNEQDEPLNSI
DDWLKKVDLMLVIGTSAQVFPAAGYIEDARDCGAVVAVINPEAENEE-EQDFAFGQDAATCLPVLLEPIIGRAQA----
>tr|J5JNW1|J5JNW1_BEAB2 Sir2 family protein OS=Beauveria bassiana (strain ARSEF 2860) GN=BBA_06225 PE=4 SV=1
------------------------------------LQSSRRVMILCGAGLSVASGLPTFRGADGYWRHHDATRLATMQAFRTDPGLVWLFYGYRRHTCL
--KAQPNAGHRALAALAKA-NPNVLCLSQNVD-LSQRAGFPPLHTLHGSLFNIKCSNCSWMQNYDDPEEELPKCPQCNT-GLQRPGVVWFGEMDPNMASI
ESWLDKVDLMLVIGTSAQVYPAAGYIDEARDRGAVVAVINPDAENDD-QNDFAFGQDAATCLPVLLEPIIGKAQA----
>tr|A0A0A1STP3|A0A0A1STP3_9HYPO Uncharacterized protein OS=Torrubiella hemipterigena GN=VHEMI03843 PE=4 SV=1
------------------------------------LRSSRRILALCGAGLSASSGLATFRGAGGYWRNYDATALASYNAFKRDPGLVWLFYAYRRHMAL
--KAKPNAAHHALTALAQK-RPEFLCLTQNVD-LSQRAQHPPLMALHGNLFNIKCSDCDWVQNVDDPRDQLPSCPKCKA-GLQRPAVVWFGETDEALRRA
DAWMETVDLMLVIGTAAQVEPAAGYIRYARKRGASVVVVNPEAESEE-EQDFAFAQDAAEYLPLLLEPVIGKAQE----
>tr|A0A0M0UAI5|A0A0M0UAI5_9PEZI NAD-dependent protein deacylase OS=Madurella mycetomatis GN=MMYC01_G05974 PE=4 SV=1
------------------------------------LARSKRILAVCGAGLSAASGLPTFRGAGGLWRNYEATTLATPEAFDEDPGLVWLFYGYRRHMAL
--RAKPNAGHYALAALARK-NPDFLCLSQNVD-LHPRASHPSLHLLHGSLFTIKCSTCNWTDNLADAASDLPRCPECRT-GLQRPGVVWFGEGDESLWAI
DDWIHIVDMVLVVGTSSVVYPAAGFAEQARTRG-RVVTVNLDAESPG-TEDFAFQGDAAEVLPRLLEPVIGKMRE----
>tr|Q0UPM0|Q0UPM0_PHANO Putative uncharacterized protein OS=Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) GN=SNOG_06294 PE=4 SV=1
------------------------------------LNKSTRILALLGAGLSASSGLPTFRGAGGLWRTHDAVQLATPGAFQADPGLVWQFYSYRRHMAL
--KAQPNPAHYALAELARKK-PGFLTLSQNVDGLSPRAHHPSLKLLHGSLFDVKCSECTHVQNYTDTYSHLPKCPACKK-GLLRPGVVWFGEQPRDLDDV
DAFMAKIDLIMVIGTSAKVYPAAGYVDLARSKGARVAIVNMDSNDVPAGGDWFFQGDAAQIMPELLESVIGEVKM----
>tr|M2LYB1|M2LYB1_BAUCO Uncharacterized protein OS=Baudoinia compniacensis (strain UAMH 10762) GN=BAUCODRAFT_119262 PE=4 SV=1
------------------------------------LKSSKRILALLGAGLSASSGLPTFRGAGGLWRTHDSISLATPEAFNKNAGLVWQFYNYRRHMAL
--QAQPNPAHYALAELARRM-PGFMTLSQNVDGLSQRANHPMLQLLHGTLFELRCVDVCRYSNFTDKREDLPTCPKCKT-NLLRPGVVWFGESPFHLEAA
EDFLNDIDIMLVIGTSAKVYPAAGYIEKARERGARVCVINMDETDRPAGGNWFFRGDAAVLVPKLLEPVIGDIKA----
>tr|A0A074WMX9|A0A074WMX9_9PEZI NAD-dependent deacetylase sirtuin-5 OS=Aureobasidium namibiae CBS 147.97 GN=M436DRAFT_44511 PE=4 SV=1
------------------------------------LQSSQRILALIGAGLSASSGLPTFRGAGGLWRTHDATSLATPEAFSRDPGLVWQFYSYRRHMAL
--KAQPNRAHLALAELARKH-PAFLALSQNVDGLSQRAKHPALQLLHGSLFNVKCTSCSYHGNFTDTTADLPLCPKCQE-GLLRPGVVWFGESPSKLNAV
DSFINKIDLIMVIGTSASVYPAAAYVDDAREKGARVAVINAARADEPAGNDWFFEGDAAQILPEILKGVIGEVEQ----
>tr|G9ML77|G9ML77_HYPVG Uncharacterized protein OS=Hypocrea virens (strain Gv29-8 / FGSC 10586) GN=TRIVIDRAFT_168778 PE=4 SV=1
------------------------------------LRSSRRILALLGAGLSADSGLPTFRGPGGYWRNYDATQLATVRAFKMDPGISWLFYAYRRHLGL
--KAEPNLGHKALAALARR-NMDFLCLTQNVD-LSQRAEHPSLKCLHGSLYDIKCSNCDWIQNFDDTEDELPKCPQCNK-GLQRPGVVWFGEDDATMMDI
SAWIRPIDLMFVIGTSAQVYPAAGYIEKARKRGARIVTINPEAEDEA-EGDFAFGRNAAECLPILLEPVIGKPDE----
>tr|G9NN09|G9NN09_HYPAI Uncharacterized protein OS=Hypocrea atroviridis (strain ATCC 20476 / IMI 206040) GN=TRIATDRAFT_81752 PE=4 SV=1
------------------------------------LRSSRRILALCGAGLSASSGLPTFRGAGGYWRNYDATSLATVRAFRTDPGMVWLFYAYRRHLAL
--KAEPNPGHRALAALARR-NLDFMCLTQNVD-LSPRAQHPSLKCLHGSLYDIKCSNCDWIQNFDDTEDELPKCPKCHR-GLQRPGVVWFGEDDSAMMDI
SAWMNPLDLMFVIGTSAQVYPAAGYIDKARKRGARIVTINPEAEDEA-EGDFAFGKDAAEYLPLLLEPIIGKPNA----
>tr|A0A024S891|A0A024S891_HYPJE Putative SIR2 family histone deacetylase OS=Trichoderma reesei RUT C-30 GN=M419DRAFT_25614 PE=4 SV=1
------------------------------------LRSSRRILALCGAGLSASSGLPTFRGAGGFWRNYDATQLATVRAFKMDPGMVWLFYAYRRHLAL
--KAEPNKGHKALAALARR-NPDFLCLTQNVD-LSQRAQHPPLKCLHGSLFDIKCSNCDWMQNFDDTEDELPKCPQCSS-GLQRPGVVWFGEDDAHMMDI
SAWLRPVDLMFVIGTSAGVYPAAGYIDKARKLGARIVIINLEAEDEA-EGDFAFGKDAAEILPVLLEPIIGKPNE----
>tr|F7W507|F7W507_SORMK WGS project CABT00000000 data, contig 2.29 OS=Sordaria macrospora (strain ATCC MYA-333 / DSM 997 / K(L3346) / K-hell) GN=SMAC_0
------------------------------------LAKADRILAICGAGLSAASGLPPSAAPLRTWRLRRRLLRRTKPEYATQVLTKETLTTQRRHMAL
--QVKPNSGHHALAALARAK-PNFLCLTQNVDNLSPRAGHPSLRTLHGSLFTLKCSS---------APSQLPQCPRCKEQSLLRPGVVWFGESDAQLKEV
DDWIDPIDIVLVVGTSSVVYPAAGYAERARTKGVTSVTVNKEVE-----EDLAFQGGAEEWLGRMFEPLIGVLGE----
>tr|Q0CI01|Q0CI01_ASPTN Putative uncharacterized protein OS=Aspergillus terreus (strain NIH 2624 / FGSC A1156) GN=ATEG_06683 PE=4 SV=1
------------------------------------LKRSRRVIALLGAGISASSGLPTFRGAGGLWRTYEATDLATPEAFEANPDLVWQFYSYRRHMAL
--KAQPNRAHHALAELARRN-KDFITLTQNVDGLSQRAQHPSIHLLHGSLFTVKCTSCNYSRDFTDSTDVLPKCPECKE-GLLRPGVVWFGESPTHLDTV
DSWLR-VDLILVIGTSSRVYPAAGYVDKARARGARVAVVNMDRNDVGSSGDWFFKGDAGIIVPEILKGVIGEIP-----
>tr|A0A064AHB9|A0A064AHB9_ASPOZ Sirtuin 5 OS=Aspergillus oryzae 100-8 GN=AO1008_00625 PE=4 SV=1
------------------------------------LKGRKRILALLGAGISASSGLPTFRGAGGLWRTYDATDLATPEAFEANPDLVWQFYNYRRHMAL
--KAQPNRAHYALAELAKRN-KNFITLSQNVDGLSQRAGHPLLHLLHGSLFTVKCTSCSYSRDFTDSSDVLPHCPECKD-GLLRPGVVWFGESPLQLDMV
DSWMR-IDLILVIGTSSRVYPAAGYVDKARARGARVAVVNMDRNDVGSSGDWFFQGDAGTIVPEILKEIIGEI------
>tr|A1CTI6|A1CTI6_ASPCL SIR2 family histone deacetylase, putative OS=Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1
------------------------------------LKGCKRIIALCGAGLSASSGLPTFRGAGGLWRSYEAMDLATPEAFEANPDLVWHFYSYRRHMAL
--KAKPNRAHYALAELARRN-RDFITLTQNVDDLSQRANHPSLHLLHGSLFTVKCTSCTYIQEFTDSRNALPHCPECKE-GLLRPGVVWFGESPSQLRAV
DKWMDKVDLILVIGTSSRVYPAAGYVDRARQLGAKVAVINMDRNDVGSSGDWFFQGDAGVIIPEILKPVIGGL------
>tr|A0A074X3M0|A0A074X3M0_AURPU DHS-like NAD/FAD-binding domain-containing protein OS=Aureobasidium pullulans EXF-150 GN=M438DRAFT_326858 PE=4 SV=1
------------------------------------LRNSKAVLALLGAGLSASSGISTYQGSGSTWQNHLVRDLATKSRFERDPVLVWEYYRHRQAEIL
--SGVPNAGHFALAGLATIK-PDFLTITQNVDDLSQRARHPPLVPIHGSLLDLHCTNCAFSRNSHDPSPPTPSCPLCT--SLLRPSITRFGDPPPSLSTV
DSWFSTIDLMLVIGCACTVSPAADYIDKAKEKGARIAVFNVEFGRQALCEDWFFEGDAGVMVPLLLGKVVG--------
>tr|A0A0K8LII6|A0A0K8LII6_9EURO NAD-dependent protein deacylase OS=Neosartorya udagawae GN=AUD_6927 PE=4 SV=1
------------------------------------LKGCKRILALLGAGISASSGLPTFRGAGGLWRSYEATDLATPEAFEADPGLVWQFYSYRRHMAL
--KAKPNRAHYALAELARRN-KDFITLTQNVDGLSQSANHPSLHLLHGSLFTVKCTSCNYLRDFTDSQDVLPHCPECKE-GLLRPGVVWFGESPLHLEMV
DNWINGVDLILVIGTSSRVYPAAGYVDKARARGARVAVVNMDRNDVGHSGDWFFQGDAGVVVPEILKGVIGDI------
>tr|A0A074XTE2|A0A074XTE2_AURPU SIR2 family histone deacetylase OS=Aureobasidium pullulans EXF-150 GN=M438DRAFT_268577 PE=4 SV=1
------------------------------------LQSSKRILALLGAGLSASSGLPTFRGAGGLWRTHDATSLATPEAFNADPALVWQFYSYRRHMAL
--KAQPNRAHLALAELARKN-PGFMTLSQNVDGLSQRAKHPSLQLLHGSLFNVKCTSCSYHANFTDKISDLPKCPECHK-GLLRPGVVWFGEAPSKINTV
DDFIVKIDLIMVIGTSAKVYPAAGYVDRARAKGARVAVINADRADAPAGSDWFFEGDAAQIVPEILRSVIGEIEQ----
>tr|E4ZJ96|E4ZJ96_LEPMJ Similar to NAD-dependent deacetylase sirtuin-5 OS=Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8) GN
------------------------------------LNKSTRILALLGAGLSASSGLPTFRGAGGLWRTHDATSLATPEAFERDPGLVWQFYSYRRHMAL
--KAKPNPAHYALAELARKK-SEFVALSQNVDGLSPRAHHPSLKLLHGSLFDVKCSECNYVENYTDDLAHLPKCPQCKR-GLLRPGVVWFGEAPSSLSDI
DAYIKRIDLIMVIGTSAQVYPAAGYVQLACMRGARVATVNMEASDIP-GGDWFFQGDAAQILPEILKSVIGELGV----
>tr|E3RVZ8|E3RVZ8_PYRTT Putative uncharacterized protein OS=Pyrenophora teres f. teres (strain 0-1) GN=PTT_13395 PE=4 SV=1
------------------------------------LNKSTRILALLGAGLSASSGLPTFRGAGGMWRTHDATSLATPQAFERDPGLVWQFYSYRRHMAL
--KAKPNPAHYALAELARKR-EEFITLSQNVDGLSPRAQHPILKLLHGSLFDVKCSDCKYVENYTDDYSHLPHCPACKT-GLLRPGVVWFGEAPKDMEDV
DDFISAVDLIMVIGTSARVYPAAGYVDQARMKGARVAVINMDPEDIPAGGDWFFQGDAARIVPELLKSVIGEIDI----
>tr|A0A0L1HV33|A0A0L1HV33_9PLEO Nad-dependent deacetylase sirtuin-5 OS=Stemphylium lycopersici GN=TW65_03484 PE=4 SV=1
------------------------------------LNKSTRILALLGAGLSASSGLPTFRGAGGMWRTHDATSLATPGAFDRDPGLVWQFYSYRRHMAL
--KAKPNPAHYALAELARKK-PEFITLSQNVDGLSPRAKHPALKLLHGSLYDVKCSDCKYFENFTDDYAHLPHCPECKR-GLLRPGVVWFGEQPGKIEDV
EDFIQGVDLIMVIGTSAKVYPAAGYVDLARDYGARVAIINMDPNDIPAGEDWFFEGDAAQIVPELLKSVIGDIDP----
>tr|W6XSA5|W6XSA5_COCCA Uncharacterized protein OS=Bipolaris zeicola 26-R-13 GN=COCCADRAFT_9109 PE=4 SV=1
------------------------------------LAKSTRILALLGAGLSASSGLPTFRGAGGLWRTHDATSLATPEAFERDPALVWQFYSYRRHMAL
--KAKPNAAHYALAELARKK-DEFITLSQNVDGLSPRAQHPPLKLLHGSLFDVKCSDCKHFENFTDDYSHLPPCPECKR-GLLRPGVVWFGEAPRSIDDV
DAFMSGIDLIMVIGTSAKVYPAAGYVDLARSKGARVAIINMDLNDVPASGDWFFQGDAAQIVPDLLRNIIGDIDP----
>tr|A0A0B2X1T0|A0A0B2X1T0_9HYPO NAD-dependent histone deacetylase, silent information regulator Sir2 OS=Metarhizium album ARSEF 1941 GN=MAM_02788 PE=4 SV=1
------------------------------------LLSSRLILALCGAGLSASSGLPTFRGAGGLWRMHSPTKLATMRAFKTDPGLVWLFYGYRRHLAL
--KANPNPGHQALAALARK-NADFLCLTQNVD-LSQRANHPTLCALHGSLFDVKCTTCGWVQNFDDPEEELPKCPKCQT-GIQRPGVVWFGEEDENMEHI
NGWITKIDLMLVIGTSAQVYPAAGYISRARLHGARVCTVNPDAEQET-EGDFAFGQDAAEALPRLLEPVIGTLQQ----
>tr|A0A0F7ZP01|A0A0F7ZP01_9HYPO Uncharacterized protein OS=Hirsutella minnesotensis 3608 GN=HIM_05990 PE=4 SV=1
------------------------------------LRSSRRILALCGAGLSATSGLPTFRGPGGYWRNHDATKLATMEAFRTDPGLVWLFYGYRRHMCL
--RAEPNAAHRALAALARK-DRDFLCLTQNVD-LSQRAGHPALCTLHGSLFDIKCSNCGWIQNYDDSEEELPVCPQCEV-GLQRPGVVWFGEEDKKLADI
DEWMDKVDLMLVVGTSAQVWPAAGYISKAKRRGARIVTINPEAEDEA-EGDFAFGRDAAECLPQLLEPVIGKMNE----
>tr|A0A0B4ID48|A0A0B4ID48_9HYPO NAD-dependent histone deacetylase, silent information regulator Sir2 OS=Metarhizium guizhouense ARSEF 977 GN=MGU_00648 PE=4 SV=
------------------------------------LRSSRRILALCGAGLSASSGLPTFRGAGGLWRMHSPTKLATMRAFSTDPGLVWLFYGWRRHLAL
--KAKPNPGHEALAALAKK-NPDFLCLTQNVDSLSQRANHPPLCTLHGSLFDIKCTTCGWIQNFDDPEEELPKCPKCQT-GIQRPGVVWFGEEDENIENI
DEWITKIDLMLVIGTSAQVYPAAGYISEAKLHGARICTINPEAEEET-EGDFAFGQDAADALPRLLEPVIGKLQE----
>tr|A0A0F4YUP0|A0A0F4YUP0_TALEM SIR2 family histone deacetylase OS=Rasamsonia emersonii CBS 393.64 GN=T310_4442 PE=4 SV=1
------------------------------------LKGCTHILALLGAGLSASSGLPTFRGAGGLWRSYDATSLATPEAFDASPDLVWQFYSYRRHMAL
--KAKPNRAHYALAELAKRN-KNFITLTQNVDGLSQRADHPPLHLLHGSLFDIKCTSCNYSRDFTDRIEDLPQCPQCK--GLLRPGVVWFGESPAHIHVV
DEWISRIDLMLVIGTSAKVWPAAGYVDIARAKGARVAVINMDPNDIPGSGDWFFQGDAGVIVPEILKSVIGEI------
>tr|F9XGE3|F9XGE3_ZYMTI Uncharacterized protein OS=Zymoseptoria tritici (strain CBS 115943 / IPO323) GN=MYCGRDRAFT_86704 PE=4 SV=1
------------------------------------LQESRSIIALVGAGLSASSGLAVFTGADGLWENQDPFSLATPEAFRSDAARVWRFYDRRRHEAL
--QAQPNAAHFALAEASRQL-PGFITMNQNIDGLSERADHPGLLALHGSLFEVQCTNSCEYWDFTYQLQGLPNCPRCN--SILRPGVVWFGERKDELLRI
RHSFSKIDLMLVIGTAAQVMPAAGYIDVARARGARLCFVNTDRNTGTGGGDWFFEGDAAVIVPILLEPVTSQGSR----
>tr|N1Q9E5|N1Q9E5_PSEFD Uncharacterized protein OS=Pseudocercospora fijiensis (strain CIRAD86) GN=MYCFIDRAFT_76862 PE=4 SV=1
------------------------------------LVGCKRVIALSGAGLSAASGLATFRGAGGLWRSHDATSLATPGAFNRDPALVWRFYSYRRHKAM
--QADPNAAHYALAQLARRL-PGFQHLSQNVDGLSQRANHPRLQLLHGTLFEVKCNNCEYQENFVDPLEDLPQCPRCND--LLRPGVVWFGEQPTQLANV
DDYFDDVDLIMVIGTSAKVYPAAGNISRARMTGARVCVVNMDENDAPAGGDWFFKGDAGTIVPELLRPIIGDVKM----
>tr|A0A0A2KXD9|A0A0A2KXD9_PENIT Sirtuin family OS=Penicillium italicum GN=PITC_076310 PE=4 SV=1
------------------------------------LGGCKRILALLGAGISASSGLPTFRGAGGLWRAHDATSLATPEAFDETPDLVWQFYSYRRHMAL
--QADPNKAHYALAELSRRN-EDFITLSQNVDGLSQRANHPSLHLLHGTLFNVKCTNCNYSGNYTDNEEDLPQCPRCKD-GLLRPGVVWFGEPPEKLKAV
DKWIA-IDLCLVIGTSARVWPAAGYVHEARSQGARVAVCNMDPKDTPGEGDWFFQGDAGVIVPEILKSVIGEI------
>tr|A0A0F7VIX0|A0A0F7VIX0_9EURO Putative Sirtuin 5 and related class III sirtuins OS=Penicillium brasilianum GN=PMG11_05101 PE=3 SV=1
------------------------------------LKGCRRILALLGAGISAASGLPTFRGAGGLWRQYDATSLATPEAFADHPGLVWQFYSYRRHMAL
--QAQPNKAHYALAELARRN-KDFITLSQNVDGLSQRAQHPSLNLLHGSLFDIKCTSCNYTCDFTDAPADLPRCPECK--GLLRPGVVWFGEPPTDIKNV
DDWIE-VDLILVIGTSSSVYPAALYVDVARERGAKVVVVNMEKDMPN-RCDWFFQGDASVIVPEILKSVIGDV------
>tr|S7ZTN1|S7ZTN1_PENO1 Uncharacterized protein OS=Penicillium oxalicum (strain 114-2 / CGMCC 5302) GN=PDE_08741 PE=4 SV=1
------------------------------------LKGCRRILALLGAGTSAASGIPTFRGTGGLWRQYDATALATPEAFENDPGLVWQFYSHRRHMAL
--RAQPNRAHHALAELARRN-KDFVTLSQNADGLSQRAQHPSLNLLHGSLFDIKCTSCHYTRDFSDAPDDLPRCPECK--GLLRPGVVWFGEPPTDLTRI
DDWIA-VDLILVIGTSARVYPAAEYVDIARDRGAKVALVNMEKDMPR-HCDWFFQGDASVVVPEILKGVIGDI------
>tr|A0A0J9UVG7|A0A0J9UVG7_FUSO4 Uncharacterized protein OS=Fusarium oxysporum f. sp. lycopersici (strain 4287 / CBS 123668 / FGSC 9935 / NRRL 34936) GN=FOXG_05
------------------------------------LRSSKRILALCGAGLSASSGLPTFRGAGGLWRNHDATSLATLSAFKNDPGLVWLFYNYRRHMCL
--RAEPNPAHYALAALAEK-NKDFLCLTQNVD-LSQQAGHPQLRTLHGSLFDIKCT-CDWIQNYDDSPDDIPKCPQCKI-GFQRPGVVWFGENDEVMMGI
TNWLLKVDLMLVIGTSAQVYPAAGYIDKAKRKGARIAVINPEAENEE-EGDFAFGKDAAEYLPLLLEPVIGKLET----
>tr|A0A0B7KG77|A0A0B7KG77_BIOOC Uncharacterized protein OS=Bionectria ochroleuca GN=BN869_000009968_1 PE=4 SV=1
------------------------------------LRSSRRVLSLCGAGLSASSGLPTFRGAGGLWRNYDATTLATPEAFQSDPGLVWLFYAYRRHMAL
--RAEPNKAHRYLAALSRE-KPEFLCLTQNVD-LSQRANHDLLLPLHGSLFDIKCT-CDWIQNYDDSRDELPKCPACKV-GLQRPGVVWFGEKDDALERA
DDFVNPVDMMLVIGTSAQVWPAAGYIEMAXREAPEWWLWIR---VLKTRRDFAFAGDAAELLPDMLQPVVGRLQD----
>tr|V5FNQ3|V5FNQ3_BYSSN SIR2 family histone deacetylase, putative OS=Byssochlamys spectabilis (strain No. 5 / NBRC 109023) GN=PVAR5_2185 PE=4 SV=1
------------------------------------LQGCKRILALVGAGLSASSGLPTFRGAGGLWRSHEATSLATPGAFNANPGLVWQFYSYRRHMAL
--SAQPNPAHYALAELAR-K-KDFITLSQNVDGLSQRAHHPSLHLLHGSLFDIKCTSCDYSRDFTDTPDDLPHCPKCKT-GLLRPGVVWFGESPSRLNAV
DRWID-IDLMLVIGTSSKVWPAAGYVDKARRKGAKIAVINMDANDVPQSGDWFFQGDAGAIVPEILKSVIGEV------
>tr|U4LHJ0|U4LHJ0_PYROM Similar to NAD-dependent protein deacylase acc. no. Q5AI90 OS=Pyronema omphalodes (strain CBS 100304) GN=PCON_09678 PE=4 SV=1
------------------------------------LRKSKRILAVCGAGLGASSGLPTFRGAGGMWRQHNAMELATPEAFRNHPGLVWQFYSLRRHYAL
--QAKPNAAHYALAELARRRPPQFLTLSQNVDGLSNTAGHPGIEYMHGSLFRVRCMRCRYERDVMDGTDELPRCPECKT-GLLRPAVIWFGENDPQLKRI
NQYLSPVDLCIVIGTSGTVFPTAGYAGKVKEMGGKVAVVDIDCSVRPEQADWLFEGDAAELVPKMLYPIIGDLQI----
>tr|A0A0G2ENP4|A0A0G2ENP4_9EURO Putative sir2 family histone OS=Phaeomoniella chlamydospora GN=UCRPC4_g02482 PE=4 SV=1
------------------------------------LKSSTRIFALLGAGLSASSGLPTFRGAGGLWRSHDATSLATPHAFQADPGLVWQFYSYRRNMAK
--HANPNAAHFALAELAKKLNEKFLCLSQNVDGLSQRAGHTELRLLHGSLWDVKCFDCDFVRDFEDPYSSLPHCPKCHH-SLLRPGVVWFTESPTQLGSI
SSWLDHVDLMLVIGTSSVVYPAAGYTDMARDLGARIAVVNLDAGSEELVVDWMFRGDAAMVVPELVKEVIGDM------
>tr|A5DD23|A5DD23_PICGU Putative uncharacterized protein OS=Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / 
------------------------------------LRASKRIIALVGAGLSASSGLPTFRGTQGLWKNFNMIDLATPDSFYIDPGLVWQFYSWRRQLAL
--EAQPNNGHRALAKLSHVH-KDFITITQNVDGLSARANHNPLLELHGSLFELKCTGCNYIDNFNHSEKDLPCCPVCG--ELLRPGVVWFGESPLIIDTI
DNFLQKVDLILVIGTSGTVYPANSYVERVRLQGGKVAIFNTDIEEDILQDTWGFHGDAAELLPLALEPLIGQLSE----
>tr|A0A099NZ11|A0A099NZ11_PICKU Uncharacterized protein OS=Pichia kudriavzevii GN=JL09_g3588 PE=4 SV=1
------------------------------------RSKKPSILAIVGAGLSAPSGLPASHHPDIIWRNYTAIDLATPDAFDANPALVWMYYAYRRHMAL
--NASPNRAHYLLKELSECEGLEFLTISQNMDGLSRRAGHFKLVEFHGSLFSVKCTNCFYQ-NYDDELSQLPTCPLCG--DLLRPGVVWFGESPLYVDQV
DEFIIGIDLLIIVGTSHSIWPVSSYIDIAHNQGGNIAVFNTQPDDIRSTTVWEFIGDCSSTLPKVFNPIINLYKK----
>tr|N1QHM7|N1QHM7_SPHMS DHS-like NAD/FAD-binding domain-containing protein OS=Sphaerulina musiva (strain SO2202) GN=SEPMUDRAFT_56413 PE=4 SV=1
------------------------------------LKKSSRVMCLVGAGLSSASGLPTFRGAGGLWRTHDAVSLASPAAFAKDPALVWRFYSYRRHMAL
--QALPNAAHYALAELARRM-PGFITLSQNVDGLSQRAGHPRLQLLHGTLFEVKCTDCGYAANFVDPPEGLPHCPRCTE-SLLRPNVVWFGEQPVALDRL
DEYLNHIDLIMVIGTGAKVYPAAGYIDHARYRSAKVCVVNMDPNDVPPGGDWFFQGDAAQLVPELLRPIIGNLPS----
>tr|F9XAW1|F9XAW1_ZYMTI Uncharacterized protein OS=Zymoseptoria tritici (strain CBS 115943 / IPO323) GN=MYCGRDRAFT_42036 PE=4 SV=1
------------------------------------LSRSKRVLSLLGAGLSASSGLPTFRGAGGLWRSHDSMSLATPQAFAADPALVWRFYSYRRHMAL
--TVRPNPAHYALAALARKL-PGFVTLSQNVDGLSPRAEHPKLKLLHGSLFEVKCNDCGYVENYTDSREDLPTCPQCRR-ALLRPGVVWFGEAPDDVDSV
YAYLDKVDLIMVIGTGAKVYPAAGYIEEAREKGAKVCVVNMDANDAPPGGDFFFQGDAATIVPELLRPIIGEVKV----
>tr|B8LYM0|B8LYM0_TALSN SIR2 family histone deacetylase, putative OS=Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006) GN=T
------------------------------------LQRSTRILALLGAGLSASSGLPTFRGAGGMWRTFDAMLLATPGAFNDNPGLVWQFYSHRRHMAL
--NAKPNRAHYALAKLAQKN-KHFITLSQNVDGLSHRADHPPLHLLHGSLFDLRCTGCNYSTDFTDQAEDLPKCPECG--GLLRPGVVWFGEGPSHLREI
DDWIAQIDLMLVIGTSSKVWPAAGYVDYAREKGARVAVVNMDRNDAPGGGDWFFEGDASEIVPEILKSVIGEE------
>tr|C4JGE9|C4JGE9_UNCRE Putative uncharacterized protein OS=Uncinocarpus reesii (strain UAMH 1704) GN=UREG_01140 PE=4 SV=1
------------------------------------LKHSKRIVAVVGAGLSAASGLPTFRGVGGLWRRYSAIDLATPEAFNATPGLVWQFYGYRRHMAL
--LAKPNRAHYALAALARKK-PDFITLTQNVDGLSERAGHPELQRLHGSLYTIKCANCTYSRDFTDTSDLLPPCPECAT-GLLRPGVVWFGEPAEALDFA
DKWIK-VDLVMVIGTSARVSPAACYIDDGREQGARVAVINMDRTHLPRTGDWVFEGDASVILPKLFEEIVGEIEL----
>tr|A0A0J6XY23|A0A0J6XY23_COCIT NAD-dependent deacetylase sirtuin-5 OS=Coccidioides immitis RMSCC 2394 GN=CIRG_01276 PE=4 SV=1
------------------------------------LRSSKRVMAVIGAGLSAASGLPTFRGVGGLWRRYSAVDLATPEAFNATPGLVWQFYGYRRHMAL
--LAKPNRAHYALAEFAKKN-PNFIALTQNVDGLSERAGHPEIQRLHGSLFTIKCANCTYSRDFTDREEDLPPCPECST-GLLRPGVVWFGEPVEEINTV
EDWLK-VDLVLVIGTSARVFPAVSYIDRGRCKGARVAIINMDRTHLPRTGDWIFEGDASAIIPELLKEVVGEIEL----
>tr|J3PBK7|J3PBK7_GAGT3 Uncharacterized protein OS=Gaeumannomyces graminis var. tritici (strain R3-111a-1) GN=GGTG_10879 PE=4 SV=1
------------------------------------VEGRGRVLALCGAGLSASSGLLTFRGKGGMWRNHRSTDLATPEAFAENPGLVWLFYAWRRHRAL
--SVQPNAAHYALARLATRLTTRFLCLTQNVDGLSQRAGHPPLRPVHGRLFDLKCFDCGYVENFSDAASDLPACPRCAKAALLRPDVVWFGEPEDDLAEA
DAFVCPVELMLVVGTAATVHPAAGYIDLARRHGAVVAVVNPDPDAGR--DDFFFAEDAAEVLPRLVEKVAGMEA-----
>tr|A0A0L0N226|A0A0L0N226_9HYPO NAD-dependent protein deacylase OS=Tolypocladium ophioglossoides CBS 100239 GN=TOPH_07237 PE=4 SV=1
------------------------------------LRSSRRVLALCGAGLSASSGLPTFRGAGGYWRSHDATKLGTMRAFKTDPGMVWLFYGYRRHTCL
--RARPNPAHRALAALARE-NQDFLCLTQNVD-------HPPLRTLHGSLFDIKCSACDWVQNFDDPEEELPTCPKCKD-GLQRPGVVWFGEEDEDMKGI
NEWMNKVDLMLVVGTSAQVWPAAGYISRAKLHGARIATINPEAEDET-EGDFAFGRDAAESLPLLLEPVIGTMQG----
>tr|E5ATQ5|E5ATQ5_BURRH SIR2 family protein OS=Burkholderia rhizoxinica (strain DSM 19002 / CIP 109453 / HKI 454) GN=RBRH_00398 PE=4 SV=1
-----------------------------------FVLAHPRLFVLTGAGISTASGIPDYRDANGERKGRAP---IMLQAFLRSPTARRRYWA--RSALG
WKQAKPSAAHHALARLE-ALGHVEQLVTQNVDGLHRRAGQAGTIELHGNIGRAICMSCGRMHALQTDLESVPVCDHCQ--GMLKPDVVFFGEGPRRVDTA
QAALTRADAVLVVGSSLMVYSGYRFCVQAARAGKPIAAINLGRTRADPLLALKVTLPCDQALLSLLAALPSANL-----
>tr|W0P9K9|W0P9K9_9BURK NAD-dependent protein deacetylase OS=Advenella mimigardefordensis DPN7 GN=cobB PE=3 SV=1
-----------------------------------FVQQHAGLLVITGAGCSTDSGIPAYRDTEGAWMRPPP---MTFQQFMGTEAARQRYWA--RSMVG
WSKGRPNAAHQALQALE-LKGYTGLLVTQNVDGLHRQAGQSRLLELHGSLANVVCMQCDTRVNWADDLETIPPCDRCG--GILKPDVVFFGETPRRVDAV
YQALAQASAVLVVGSSLMVYSGYRFVRDAALQGKPVAAITRGRTRADAVLALKLDTACAPVLTALDAILAPLPQ-----
>tr|V8QL62|V8QL62_9BURK NAD-dependent deacetylase OS=Advenella kashmirensis W13003 GN=W822_21785 PE=4 SV=1
-----------------------------------FVHRHAGLLVITGAGCSTDSGIPAYRDTDGAWMRPPP---MTFQKFMSGEPARQRYWA--RSMVG
WSGGRPNAAHQALASLE-AKGYTGLLVTQNVDGLHRQAGQSRLLELHGSLASVICMQCQCRLDWVHDLETVPPCPRCG--GILKPDVVFFGEAPRRVDAV
YAALDKASAVLVVGSSLMVYSGYRFVRDAVRQGKPVAAITQGRTRADNVLAFKLNTACAPVLSALDTVLEPFAV-----
>tr|A0A0B8Z1Q6|A0A0B8Z1Q6_9BURK Iron dicitrate transport regulator FecR OS=Burkholderia multivorans GN=BMD20_04000 PE=3 SV=1
-----------------------------------FVERHPRLLVLTGAGISTDSGIPGYRDRNGQWTRSPP---IQLHEFLGSDVARRRYWA--RSMIG
WPRAQPNRSHTALARLG-RAGRIERLVTQNVDGLHQRAGSVDVIELHGGIHGVTCIDCGAHHALLGHLEWVPACPTCG--GLLKPAVVFFGENPRRVALA
SQALDAADALLVVGSSLMVYSGYRFCLWAQAQHKPIAALNLGRTRADPMLALKVEARCAPALEALTARLGLGLA-----
>tr|A0AE18|A0AE18_STRAM NAD-dependent protein deacetylase OS=Streptomyces ambofaciens ATCC 23877 GN=cobB PE=3 SV=1
-----------------------------------DALGAGGVLVLSGAGISTESGIPDYRGEGGSLSRHTP---MTYQDFTGSAQARRRYWA--RSHLG
WRRARPNAGHRAVAAFG-RHGLLGGVITQNVDGLHQAAGGEDVVELHGSLDRVVCLSCGAFSPFSPDLTDVVPCALCG--GVLKPDVVFFGEAPPRVEHC
RALVREAATLLVLGSSLTVMSGLRFVRQAAQAGTPVLVVNRDPTRGDTYARTRVALPLGQALTTVADRLGVPVD-----
>tr|A6WG46|A6WG46_KINRD NAD-dependent protein deacetylase OS=Kineococcus radiotolerans (strain ATCC BAA-149 / DSM 14245 / SRS30216) GN=cobB PE=3 SV=1
-----------------------------------DLLDGGRVVVLEGAGMSTGSGIPDYRGPGGSLQRHTP---MTYQEFTGSAEARRRYWG--RSHVG
WERARPNDAHRAVAALE-GAGVVTGVITQNVDGLDLAAGTREVVELHGNLDRVVCLRCGELTAFDADLTETVACRRCGE-DALKADVVFFGETPKRVARS
FELLDAARVLLVLGSSLAVMSGYRFVLHAARNGQPVAIVTAGPTRGDEKAALKVDAPLQEVLPAVLERLRLRL------
>tr|A0A0C1WWQ1|A0A0C1WWQ1_9ACTN NAD-dependent protein deacetylase OS=Streptomyces sp. AcH 505 GN=cobB PE=3 SV=1
-----------------------------------DALAAGGVLVLSGAGISTESGIPDYRGEGGSLSRHTP---MTYQDFTAGAQARRRYWA--RSHLG
WRRARPNAGHRAVAAFQ-RHGVLSGVITQNVDGLHQAAGSLDVVELHGSLDRVVCLSCRTLTPFEPDLTDVVPCTHCG--GILKPDVVFFGENPPRVEHC
RALVQAAASVLVLGSSLTVMSGLRFVRQAAQAEKPVLIVNRDPTRGDRYAHTRVTLPLGAALTSIADQLNIPMG-----
>tr|A0A0J6XQ70|A0A0J6XQ70_9ACTN NAD-dependent protein deacetylase OS=Streptomyces roseus GN=cobB PE=3 SV=1
-----------------------------------EALRDGGVLVLSGAGLSTESGIPDYRGKGGSLSRHTP---MTYQEFTGSDRARRRYWA--RSHLG
WRRARPNAGHRAVAAFE-RRGLLSGVITQNVDGLHQAAGSEGVVELHGSLERVVCLSCGTFASFEPDLTDVVPCARCA--GVLKPDVVFFGESPPRVVRC
REMVDGARSLLVLGSSLTVMSGLRFVRQAARAGKPVLIVNHDPTRGDEHALTRVALPLGPTLTALADRLDIPVG-----
>tr|A0A0N1IRR8|A0A0N1IRR8_9ACTN NAD-dependent protein deacetylase OS=Streptomyces sp. NRRL F-7442 GN=cobB PE=3 SV=1
-----------------------------------EALRAGGVLVLSGAGISTESGIPDYRGEGGSLSRHTP---MTYQDFTGSPEARRRYWA--RSHLG
WRRARPNAGHRSVAAFG-RHGLLTGVITQNVDGLHQAADSEGAVELHGSLDRVVCLSCGAFSPFAPDLTDVVPCAVCG--GVLKPDVVFFGENPPRVEHC
RELVRAASSLLVLGSSLTVMSGLRFVRQAADAGKPVLIVNRDATRGDRLALTRVALPLGPALTAVADRLGLAVP-----
>tr|A0A0B5I523|A0A0B5I523_9ACTN NAD-dependent protein deacetylase OS=Streptomyces vietnamensis GN=cobB PE=3 SV=1
-----------------------------------DALDAGGVLVLSGAGISTESGIPDYRGEGGSLSRHTP---MTYQDFTGSAQARRRYWA--RSHLG
WRRALPNAGHLAVAAFA-RRGLLSGVITQNVDGLHQAAGSGGVVELHGSLARVVCLSCGTYSPFAPDLTDVLPCANCG--GVLKPDVVFFGEAPPRVEHC
RRLVGEATSLLVLGSSLTVMSGLRFVRQAAQAGTPVLIINRDPTRGDRHALTRIALPLGAALTTLADRLGIPPA-----
>tr|A0A0Q7V4H7|A0A0Q7V4H7_9ACTN NAD-dependent protein deacetylase 1 OS=Streptomyces sp. Root55 GN=ASD51_27120 PE=4 SV=1
-----------------------------------DALRRGDVLVLSGAGISTESGIPDYRGEGGSLSRHTP---MTYQDFIAGTQARRRYWA--RSHLG
WRRARPNAGHRAVAAFG-RQGLLSGVITQNVDGLHHAAGSQGVVELHGSLERVVCLSCGAFSPFAPDLTDVVPCTVCG--GILKPDVVFFGEAPPRVERC
RELVRGAASLLVLGSSLTVMSGLRFVRQASQDGIPVFIVNLDPTRGDRYAVTRVALPLGTALTTVADGLGLRVD-----
>tr|A0A0J7ZVL8|A0A0J7ZVL8_9ACTN NAD-dependent protein deacetylase OS=Streptomyces regensis GN=cobB PE=3 SV=1
-----------------------------------GALGAGGVLVLSGAGISTESGIPDYRGEGGSLSRHTP---MTYQEFTGSAQARRRYWA--RSHLG
WRRARPNAGHRAVAAFG-RHGLLSGVITQNVDSLHQAAGSEGVVELHGSLDRVVCLGCGAFSPFEPDLTDVLPCVICG--GVLKPDVVFFGEAPPRVEYC
RKLVREAASLLVLGSSLTVMSGLRFVRQAADAGKPVLIVNRDQTRGDRHAVTRVALPLGRALTAVAGLLDIPID-----
>tr|Q82QG9|Q82QG9_STRAW NAD-dependent protein deacetylase OS=Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12
-----------------------------------RALSNGGVLVLSGAGISTDSGIPDYRGEGGSLSRHTP---MTYQDFTAGVQARRRYWA--RSHLG
WRRARPNAGHRAVAAFA-RHGLLSGVITQNVDGLHQAAGSESVVELHGSLERVVCLSCGAFTPFEPDLTDVVPCTACG--GILKPDVVFFGEAPARVQHC
RTLVDQATSLLVLGSSLTVMSGLRFVRQAAQAGKPVLIINRDATRGDPHAVTRIALPLGTALTTVAGRLDIPAD-----
>tr|W3RFK2|W3RFK2_9BRAD NAD-dependent deacetylase OS=Afipia sp. P52-10 GN=X566_19910 PE=4 SV=1
-----------------------------------ELISAKTIVPFTGAGISTECGIPDFRSPGGIWK-QRP---IPYDEFVSSQEARNESWK--RRFAM
EEAARPGRGHRALASLY-RAGKVPGVITQNIDNLHQSSDATDVIELHGNTTYARCIGCAKRYE---FNN-APSCPACD--DPIKTATISFGEAPEPMQRA
TELAQDCDLMLAIGSSLVVWPAAGFPLLAKRSGAKLAIINIQPTDQDDLADLVIRFDIGETLGPFVGN-----------
>tr|D1BKD9|D1BKD9_SANKS NAD-dependent protein deacetylase, SIR2 family OS=Sanguibacter keddieii (strain ATCC 51767 / DSM 10542 / NCFB 3025 / ST-74) GN=
-----------------------------------DLLRGRRFAVLTGAGVSTDSGIPDYRGPDSP--PRNP---MTYQQFIGDESFRRHYWA--RNHVG
WRRTSPNEGHRALTRLE-QAGLVTGIITQNVDTLHVVAGAENVVDLHGSFDRVVCLDCGHVVSFVEVIETPVACEVCG--GTLKPDIVYFGEMPKRVARA
FAMVDEAEVLLVAGSSLTVHSGLRFVKHAAKAGIPVIIVNRGETRGDPLATLTVDAGATQTLEAIARALAP--------
>tr|A0A0Q9CYC7|A0A0Q9CYC7_9CELL NAD-dependent deacetylase OS=Oerskovia sp. Root918 GN=ASE27_01290 PE=4 SV=1
-----------------------------------HLLRGKRLTALTGAGISTDSGIPDYRGPDSP--PRNP---MTYQQFVGDEAFRRHYWA--RNHVG
WQRTHPNGGHKALVRLE-ERGVLEGIITQNVDLLHEDAGSRNVIDLHGRYDRVICLSCSRVVSFLEVIESPAACEFCG--GMLKPEIVYFGENPRRVERA
YAMVDAADALLVAGSSLTVMSGLRFVKHAVKTDKPVVIVNRGATRGDPLATIKLEAGVSETLEELADRL----------
>tr|L9WU22|L9WU22_9EURY Silent information regulator protein Sir2 OS=Natronorubrum bangense JCM 10635 GN=C494_01871 PE=4 SV=1
-----------------------------------ADIRADTVVAFTGAGISAPSGVPTFRGDDGVWH-FDE---GQFTRFQRDPA---GFWA--DRLEL
QRGFEPNAAHEALAAMG-TDGHLEAILTQNTDGLHADASETTLLELHGNARRVRCTDCGRRID---AAD-LPPTCDCG--GVYKPDVVLFGEQPGVIQRA
RALARESDVFLAIGSSLVVEPAASLPRLAASPETTVGIINLESTPVDSAADIVYREDVTTVLPRLRDVLEA--------
>tr|L9VUW9|L9VUW9_9EURY Silent information regulator protein Sir2 OS=Natronorubrum tibetense GA33 GN=C496_12874 PE=4 SV=1
-----------------------------------DDIDAETVVAFTGAGISQPSGVPTFRGDDGVWK-FDE---GQFTRFQRNPE---GFWA--DRIEL
QQGYEPNAAHEALAAMG-RDDNLEAILTQNTDGLHGEADEPSILELHGNSQRVRCIDCGKRME---ATN-LPPTCDCG--GVYKPDVVLFGEQPGVIQRA
RSLAGESDVFLAIGSSLVVEPAASLPRLAASSGATVGIVNLESTPVDSSADVVVREDVTDVLPKIRDLVEK--------
>tr|L9WKQ7|L9WKQ7_9EURY Silent information regulator protein Sir2 OS=Natronolimnobius innermongolicus JCM 12255 GN=C493_19851 PE=4 SV=1
-----------------------------------DEISAETVVAFTGAGISAPSGVPTFRGDDGVWK-FDE---GQFTRFQRDPE---AFWD--DRVGL
QRGYEPNAAHEALAELG-RTDHLEAILTQNTDGLHGDAPEPAILELHGNSQRVRCTGCGTRRD---AAN-LPPTCDCG--GVYKPDVVLFGEQPGVIQRA
RTLARESDVFIAIGSSLVVQPAASLPRQAASSGATVAIVNLESTPVDGAADVIRREDVTDVLPQLVELVTDSA------
>tr|M0CEC2|M0CEC2_9EURY Silent information regulator protein Sir2 OS=Haloterrigena limicola JCM 13563 GN=C476_07786 PE=4 SV=1
-----------------------------------DDIRAETVVALTGAGISAPSGVPTFRGDDGVWR-FDE---GQFARFQRDPA---GFWA--DRVDL
QQDPDPNAAHEALAAMG-HAGALEAICTQNTDGLHGVAATTTILELHGNAQRVRCQDCGSRRD---AAA-LPPTCDCG--GVFKPDVVLFGEQPGAIQRA
RSLARESDVFLAIGSSLRVQPAASLPQLAAETDATVGIVNLDSTPYDSLADVVYREDVTTVLPRLRELVAE--------
>tr|L9Y0R6|L9Y0R6_9EURY Silent information regulator protein Sir2 OS=Natrinema versiforme JCM 10478 GN=C489_09817 PE=4 SV=1
-----------------------------------DEIDAETVVAFTGAGISAPSGVPTFRGDDGVWR-FDE---GQFARLQRDPA---GFWA--DRVDL
QRGFEPNAAHEALAAMG-RDGDLEAILTQNTDGLHGEAGEPTVLELHGNSQRVRCTDCGKRRN---AAE-LPPTCDCG--GVFKPDVVLFGEQPGVIQRA
RSLARESDVFLAIGSSLVVEPAASLPRLAASTGATVGIVNLGSTPRDDIAAVVSRADVTDALPRLRALVAE--------
>tr|L0K1L7|L0K1L7_9EURY NAD-dependent protein deacetylase, SIR2 family OS=Natronococcus occultus SP4 GN=Natoc_2678 PE=4 SV=1
-----------------------------------EAINADTAAALTGAGISAPSGIPTFRGEDGVWR-FDE---GQFTRFRSDPE---GFWA--DRLEL
QEGYEPNAGHEALAALE-RDGHLEAICTQNTDGLHADAAAESVLELHGNARRVRCTDCGRRRE---AAD-LPPTCGCG--GVFKPDVVLFGEQPGVIQRA
RSLARESDAFLAIGSSLAVEPAASLPRQASSSGATLGIVNLESTSCDEAAAVVHREDVAEALPRLRELIEG--------
>tr|L9Z921|L9Z921_9EURY Silent information regulator protein Sir2 OS=Natrinema gari JCM 14663 GN=C486_06603 PE=4 SV=1
-----------------------------------DAIRADTVVAVTGAGLSAPSGVPTFRGDDGIWR-FDE---RQFARFRRDPA---GFWA--DRVAL
EREYEPNVGHEALAAMG-RDGNLEAILTQNTDGLHGDATGTTVLELHGNSRRVRCTDCGTRRD---AAA-LPPTCECG--GVFKPDVVLFGDRPDVFQRA
RALARESDAFLAIGSSLVVEPAASLPRLAASTGATVAIVNLEPTPCDGLAETVLREDVTAVLPRLRDLTTA--------
>tr|M0BNM7|M0BNM7_9EURY Silent information regulator protein Sir2 OS=Haloterrigena thermotolerans DSM 11522 GN=C478_10713 PE=4 SV=1
-----------------------------------TAVDADTAVAFTGAGISAPSGVPTFRGDDGVWQ-FDQ---GQFARFQRDPE---GFWA--DRVDL
QRGFEPNAAHEAVAAMG-RDGHLEAVLTQNTDGLHGDADEPTILELHGNSQRVRCTDCGKRTD---AAG-LPPTCDCG--GVFKPDVVLFGEQPGVLQRA
RSLARESDAFLAIGSSLVVEPAASLPRLAASTGGTVGIVNLESTPCDDVADAVVREDVTEALPRLQELIVE--------
>tr|A0A086DYV6|A0A086DYV6_9MICO NAD-dependent deacetylase OS=Cryobacterium sp. MLB-32 GN=JF66_10050 PE=4 SV=1
-----------------------------------AILHGKQTVVLTGAGVSTDSGIPDYRGEGAP-V-RNP---MTFQTFAGNERARKRYWA--GSHLG
WRAAQPNLGHDSLVLLE-RAGIVSGIITQNVDGLHTRAGSRHVVELHGSMDRVICLVCGQAFGLNSDVDDIPACTVCG--GMLKPNVVFFGEFPTRFASA
QSLVQGADALIVAGSSLAVNSGIRLLEQARRRKLPIIVINRGATKGDGRAVLKLEAGTSETLAGLAERLCP--------
>tr|A0A0Q4SVL2|A0A0Q4SVL2_9ACTN NAD-dependent deacetylase OS=Aeromicrobium sp. Leaf245 GN=ASF05_10975 PE=4 SV=1
-----------------------------------RIVSAGRLLVLTGAGVSTDSGIPDYRGPGRL-STPTP---MTIQQLRSGPEAMQRYWA--RAHLG
WSHAEPNATHHTLVEWE-REGRLVGLVTQNVDGLHERAGHQDVVDLHGRVDRVLCMDCGDVTPWSDQLDDVAPCRVCG--GRLRPDVVFFGGSPKVVEHC
FDLVAQASAVLVLGSSLHVMSGLRFVRRAAALGTPVVVVNRGPTRGDPLATVKIDAGCAETLGDLAIAFA---------
>tr|D3Q5P5|D3Q5P5_STANL Silent information regulator protein Sir2 OS=Stackebrandtia nassauensis (strain DSM 44728 / NRRL B-16338 / NBRC 102104 / LLR-40
-----------------------------------APLEYSRVVVLTGAGISRPSGLPTYRGDDGTWD-PEA---ARAATVGTDLA---AVWR--LWGGL
AHAAQPNPAHRALAGAE-ESLASLLVVTQNVDGLHQRGGQRDVIELHGNAHRQRCLDAGCALV---VGT-IPSCAGCG--GRARPDIVLFGEQDLDLERA
WNTAAEADLLLAVGTSCGVSPAANLVAVARQAGALCVALTREPLPFNPGFHAAVTGLAERELPRWVAETR---------
>tr|A0A0Q7PWP2|A0A0Q7PWP2_9ACTN NAD-dependent deacetylase OS=Aeromicrobium sp. Root495 GN=ASD11_15950 PE=4 SV=1
-----------------------------------DVLPETGVLVLTGAGVSTDSGIPDYRGPGSV--PRSP---MTYQEFIATPEAHQRYWA--RAHVG
WSTAEPNATHHALVAMQ-REGRLHGLITQNIDGLHESAGHQDVIDLHGRIDRVRCIDCDARTRWTEELDEVAPCEACG--GRLKPDVVFFGESPKLVQHC
FDLTESARALLVLGSSLHVMSGLRFVRRAHALRIPVVIVNRGTTRGDDLATVKLDAGCAETLAAWTDLVGT--------
>tr|A0A0Q6VNQ0|A0A0Q6VNQ0_9ACTN NAD-dependent deacetylase OS=Aeromicrobium sp. Root344 GN=ASC61_07350 PE=4 SV=1
-----------------------------------DVLGDRRWLVLTGAGVSTDSGIPDYRGPGSP--VRTP---MTYQDFVRTPEGRQRYWA--RAHVG
WSGAEPNATHRALVELE-RQGRLTGLITQNVDGLHERAGHRDVIDLHGRIDRVICLQCREVTPYESVLDDVAECRTCG--GDLKPDVVFFGENPKRVERS
YALVAEAEALVVLGSSLQVMSGLRFVRAAHKRSIPIAIINRGTTRGDDLATVKLEAGCAETLAALNGTTAPA-------
>tr|E2S8I5|E2S8I5_9ACTN NAD-dependent protein deacetylase OS=Aeromicrobium marinum DSM 15272 GN=cobB PE=3 SV=1
-----------------------------------ELLAAGRVLVLTGAGVSTDSGIPDYRGPGAP--VRAP---MTFSEFVHSAEARQRYWA--RAHVG
WSSAAPNATHLRLVELD-RAGILAGLVTQNVDGLHSKAGHPGVIDLHGRVDRVICLDCSQVVPWTEVLEEVAACEACG--GRLKPDVVFFGESAKLVAHC
FALTEAASAVVVLGSSLQVMSGLRFVRRAASLGIPVAIVNRGPTRGDDLADVRIDAGCAETLLSVAGATLAP-------
>tr|A0A0F0LJX3|A0A0F0LJX3_9MICO NAD-dependent protein deacylase OS=Microbacterium azadirachtae GN=cobB PE=4 SV=1
-----------------------------------ELLADRRIAFLTGAGLSTDSGIPAYRGAGST-PRRTP---MTVQTFLGSEDAQRRYWL--GGHLG
WRTAVANPGHRAIAGLE-RAGRAVGAITQNVDGLHLAAGSARVVELHGTMRTVLCLHCGQSFSLDVRPETLPVCTVCA--GPLKPDVVFFGEYPTRFATA
EALLRSGDALIVAGSSLVVNSGIRIIERARRRSLPIVIINLEPTRADAWASATIAASTSLVLPALLELLT---------
>tr|A0A0F0KEX1|A0A0F0KEX1_9MICO NAD-dependent protein deacylase OS=Microbacterium azadirachtae GN=cobB PE=4 SV=1
-----------------------------------ELLADRRIAFLTGAGLSTDSGIPAYRGAGSS-PRRAP---MTVQTFLGSAQAQRRYWL--GGHLG
WRAAEANAGHRAIAGLE-KAGRSAGVITQNVDGLHLAAGSERVVELHGTMRTVLCLRCGQTFALDVRPESLPICTVCG--GPLKPDVVFFGEFPTRFATA
EALLRSGDALIVAGSSLVVNSGIRIIERARRRGLPIVIVNLEPTRADAWASATIAASTSVVLPALQELLT---------
>tr|A0A0Q9SXG3|A0A0Q9SXG3_9MICO NAD-dependent protein deacetylase 1 OS=Phycicoccus sp. Soil802 GN=ASG91_11115 PE=4 SV=1
-----------------------------------ALLERGDVLVLTGAGISTDSGIPDYRGPDGT-RRVTP---MQYAEFLGSSQARQRYWA--RSYVG
WQLARPNSGHEAVARLQ-RCGLVGPVITQNVDGLHQQAGATDVEELHGSLARVVCLTCGDRSSFTVVLNETPLCLVCGH-DTLKPDVVFFGESPKLVEKC
FRHTEEASALVVLGSSLKVMSGYRFVRRAAALDIPVAIITRGPTRGDEQASVQVDAPLGPTLAALLDRVAA--------
>tr|A0A0L6CNB6|A0A0L6CNB6_9MICO NAD-dependent protein deacetylase 1 OS=Luteipulveratus sp. C296001 GN=VV01_06250 PE=4 SV=1
-----------------------------------ELVRTGGLVGLTGAGLSTESGIPDYRGPDGE-RRITP---MSASELLGSTQARQRYWA--RSYVG
WRRARPNVGHEVVARLQ-RRGLLGTVITQNVDGLHQEAGATDVIELHGSLDQVVCMTCGEHYRFDRVISDLVHCVICGS-DKLKPDVVMFGESPKLVERC
FREVEASRGLLVLGSSLMVMSGYRFVRRAARLSLPVAVVTRGRTRGEAETTIKVDAPLGATLQALEAALDQ--------
>tr|A0A062VMW9|A0A062VMW9_9MICO NAD-dependent deacetylase OS=Microbacterium sp. CH12i GN=DC31_14920 PE=4 SV=1
-----------------------------------DLLRGRKIALLTGAGISTDSGIPAYRGEGAR-TRADP---MTIQRYLADEAARRRYWL--GGHLG
WRAAEPNAAHIALAEME-RDGIVSGVITQNVDGLHLRAGSARVIEVHGTMRRVVCLQCGQVFDLTVAPESVPNCTVCG--GMLKPDVVFFGEYPGRFRAA
ESLLRASDALIVAGSSLVVNSGVRLVERARRRSIPMIIVNHEPTRADAWAHVTLAGGTGDVLPALQELLQ---------
>tr|A0A0L6I0N7|A0A0L6I0N7_9MICO NAD-dependent deacetylase OS=Microbacterium sp. GCS4 GN=AKH00_01810 PE=4 SV=1
-----------------------------------ELLAGRRIALLTGAGISTDSGIPAYRGEGSR-TRSDP---MTIDRYLGDEAARRRYWV--GGHLG
WRRAEPNAAHRALAAME-STGHVTGVITQNVDGLHLRAGSSHVIEVHGTMRRVTCLHCGQVFDITVLPESVPVCTVCG--GMLKPDVVFFGEYPQRFRAA
ESLLRSSDALIVAGSSLVVNSGVRLVERARRRSIPLVIINREPTRADPWADITIAAGTGDVLPALQELLP---------
>tr|A0A0M2HPM0|A0A0M2HPM0_9MICO NAD-dependent protein deacetylase OS=Microbacterium hydrocarbonoxydans GN=cobB PE=4 SV=1
-----------------------------------DLLRGRKIALLTGAGISTDSGIPAYRGEGAR-TRSDP---MTIQKYLGDEAARRRYWV--GGHLG
WRQAEPNAGHIALAEME-AGGVVSGVITQNVDGLHLRAGSSHVIEVHGTMRRVLCLHCGQVFDITVLPESVPVCTVCE--GMLKPDVVFFGEYPQRFKAA
ESLLRASSALIVAGSSLVVNSGVRLVERARRRGIPLIIVNHEPTRADTWADLTLASGTSVVLPAIQELLQ---------
>tr|A0A0Q9D9R3|A0A0Q9D9R3_9MICO NAD-dependent deacetylase OS=Microbacterium sp. Root280D1 GN=ASE34_09560 PE=4 SV=1
-----------------------------------ELLRGRKIALLTGAGISTDSGIPAYRGEGSR-NRTDP---MTIQRYLADETARRRYWV--GGHLG
WRRAEPNPGHLSLAAME-SSGHVTGVITQNVDGLHLRAGSSHVIEVHGTMRRVLCLKCGQVFDISVLPESVPVCTVCE--GMLKPDVVFFGEYPQRFKAA
ESLLRASDALIVAGSSLVVNSGVRLVERARRRSIPLIIINREPTRADVWADATIAAGTSDVLPAIRELLE---------
>tr|A0A0F2CDU8|A0A0F2CDU8_9MICO NAD-dependent protein deacetylase OS=Microbacterium sp. SA39 GN=cobB PE=4 SV=1
-----------------------------------QLLRGRRIALLTGAGISTDSGIPAYRGEGAR-TRNDP---MTIQTYLGDERARRRYWV--GGHLG
WRRAAPNPGHIALAEME-AAGTVSGVITQNVDGLHLRAGSSHVIEVHGTMRRVLCLHCGQVFDITVLPETIPTCTVCD--GMLKPDVVFFGEYPQRFRAA
ESLLRSSTALIVAGSSLVVNSGVRLVERARRRSIPLIIVNHEPTRADPWANLTIAAGTSDVLPALQELLS---------
>tr|A0A0Q7VZB8|A0A0Q7VZB8_9MICO NAD-dependent deacetylase OS=Microbacterium sp. Root553 GN=ASD43_11035 PE=4 SV=1
-----------------------------------ELLRGTRIALLTGAGLSTDSGIPAYRGEGAP-ARSNP---MTIQTYLADERARRRYWV--GGHLG
WRRAEPNAGHRALAEME-SSGVVSGVITQNVDGLHLRAGSSHVIEVHGTMRRVLCLRCGQVFDITVLPETIPVCTVCE--GMLKPDVVFFGEYPLRFRAA
ESLLRSSTALIVAGSSLVVNSGVRLVERARRRGIPLIIVNHEPTRADTWAHVTIAAGTSDVLPALQEMLR---------
>tr|A0A010ZLA0|A0A010ZLA0_9ACTN NAD-dependent protein deacetylase OS=Cryptosporangium arvum DSM 44712 GN=cobB PE=3 SV=1
-----------------------------------TLVRDGDVVVLSGAGLSTESGIPDYRGPSGAFRNHTP---MTYQAFTRDVVARRRYWA--RSFLG
WRRAEPNDGHRAVAALQ-RNGLVGSIITQNVDGLHQAGGADRVIELHGSLDHVICLDCGEHTPFGHDLPEVVDCTGCG--GVLKPDVVFFGESPKRVARC
QQAVAEAGLLLVLGSSLTVYSGRRFVVQAKQAGVPVAIINSGPTRGDEHALVRIDAPLGSTLTALAAATT---------
>tr|A0A0C5BEH2|A0A0C5BEH2_9MICO NAD-dependent deacetylase OS=Rathayibacter toxicus GN=TI83_06560 PE=4 SV=1
-----------------------------------TLLQGHTIAALTGAGISTDSGIPDYRGAGAP-V-RSP---MTYSQFIADPHYRRRYWA--GSQLG
WRNSLPNDGHRALVSLE-EHGVLTGIVTQNVDGLHVRAGSRRVVDLHGSADRVRCLVCGQYFALDDEVEDVPDCSVCG--GLLKPDIVFFGEFPARFQEA
RVIVTSATALLVVGSSLVVNSGIRFLEIARRAKLPIVIINRGATRGDSRASVTVNGGASEILSDLAERLTGQ-------
>tr|A0A095YW46|A0A095YW46_9ACTO NAD-dependent deacetylase OS=Actinomyces sp. S4-C9 GN=HMPREF1628_07835 PE=4 SV=1
-----------------------------------DMMRENTTAIIAGAGMSTDAGIPDYRGTG---SGGQT---VDFDLFMSDPKWQRWVWQ--RNQET
WKGLSPTRAHLAVAALQ-KAGYVNGIATQNVDGLDVRAGIDRPALLHGTFDTADCVMCGANYPVVDAGANVAPCPKCG--GPLKPSVVFFGEMPAAMDLA
FQYAREAGVLLVVGSSMIVGTGVWVAQKGLRNGTKLVVINRGPTQIDAYADLRIEGGASQILTAVAEKLGVEV------
>tr|A0A0K9ETN5|A0A0K9ETN5_9ACTO NAD-dependent deacetylase OS=Actinobaculum suis GN=ACU19_05605 PE=4 SV=1
-----------------------------------ELMRGKTTVAITGAGISTDSGLPDYRGKG---TQEPS---VYFDDFARDPVWQRWVWQ--RNQET
WRNISPNAGHIAIARLE-KAGLINGIATQNVDDLHQKAGSTKVAELHGSFLRADCLQCGASYAWPEEAAQVAPCPRCG--GVIKPAIVFFGESPQAMHQS
FAWAGAADLALVVGTSLMVGTGMMVLGEALQNGVQCAIVNMGPTQADNYADLRIDGDAGPILARTAEILLD--------
>tr|K9ECS5|K9ECS5_9ACTO Uncharacterized protein OS=Actinobaculum massiliense ACS-171-V-Col2 GN=HMPREF9233_00835 PE=4 SV=1
-----------------------------------ELMRGKTTVAITGAGISTESGLPDYRGKG---TEEPS---VYFDDFESDPVWRRWVWQ--RNTET
WRALEPNEGHIAIARLE-KAGLINGIATQNVDNLHQKAGSRKIAELHGSFARVTCLGCGREFSWPTAAAEPADCPKCG--GILKPSVVFFGESPAAMRQS
FDWAGKADVALVVGTSLMVLTGMWVMGEALQHGAQCAIINLGPTQGDRYADLRIEGNAGPVLTHTADILLS--------
>tr|A0A068NJD3|A0A068NJD3_9ACTO NAD-dependent deacetylase OS=Actinotignum schaalii GN=FB03_05905 PE=4 SV=1
-----------------------------------ELMAGRTTVVIAGAGVSTASGIPDYRGTG---SDAPS---IDYDAFVSDPVWQRWVWQ--RNQET
WRGVVANDAHTALARFE-KAGLINGVATQNVDNLHQKAGSTRLAELHGNFLRVVCVECGAEFPWPEAGAEVAPCPRCG--GLLKPAVVFFGEAPRAMEQS
FAWAREADVALVVGTSLAVLTGSWVLGEALQHGAACAIINIGPTTADRYADLRVEGDVGTVLAGAADLLGA--------
>tr|K0Z3L8|K0Z3L8_9ACTO Uncharacterized protein OS=Actinomyces neuii BVS029A5 GN=HMPREF9240_01103 PE=4 SV=1
-----------------------------------SLMRGRKTVVIAGAGLSTDAGIPDYRGTG---GDRPS---VEFDDFVSDPVWQRWVWM--RNQQT
WRTLSPTPGHQALAQLE-KAGLVSAVATQNVDGLDARAGIQNLYELHGSFNRVRCLKCGQYFSLKPTAAELAPCTICG--GLLKPDVIFFGEQPMAMENS
FAAAATADVMLTVGSSLMVMTGMMVLREGAMHGAKVAIVNRGRCQGDPFADVRIEGGASEALTGLAERLLGAN------
>tr|A0A0Q8V8V9|A0A0Q8V8V9_9MICO NAD-dependent deacetylase OS=Leifsonia sp. Root227 GN=ASE16_09225 PE=4 SV=1
-----------------------------------ELLAGRRFALLTGAGVSTDSGIPDYRGEGAP-K-RTP---MTFQQFLADDTYRKRYWA--GSHLG
YRAAAPNDGHRAIAALE-LGGAANGVVTQNVDGLHKQAGSRKVVDLHGAMDRVLCLVCGQIFALDAIVTDVPDCTVCG--GHLKPDVVFFGEFPAKYREA
SALVRSSDALLIAGSSLAVNSGIRLLEEARRRKLPIVIVNRGETKGDGRATIKLNAGTTETLVELAARLT---------
>tr|U2SXB9|U2SXB9_LEIAQ Transcriptional regulator, Sir2 family OS=Leifsonia aquatica ATCC 14665 GN=N136_03765 PE=4 SV=1
-----------------------------------DLLSGRRFAVLTGAGVSTDSGIPDYRGEGAP-K-RTP---MTFQQFLADDRYRKRYWA--GSHLG
YRAARPNAGHRALAALE-AAGAANGVITQNVDGLHKQAGSQRVVDLHGSMDRVVCLVCGQVFAIDTIVTDVPDCTVCG--GHLKPDVVFFGEFPAKYREA
SAMVRASDALLIAGSSLIVNSGIRLLEEARRRRLPIVIVNRGETKGDLRAAIKLDAGTTETLVELSRRLA---------
>tr|A0A0R2PPP8|A0A0R2PPP8_9MICO NAD-dependent deacetylase OS=Microbacteriaceae bacterium BACL25 MAG-120322-bin65 GN=ABR66_04470 PE=4 SV=1
-----------------------------------DILAGKRTAVLTGAGISTDSGIPDYRGEGAP-K-AHP---MTLQSFLDSPAHRKRYWL--GSHVG
WGGATPNAGHTAIARAE-ETSIFSGVITQNVDALHHKAGSLRVVDLHGRLDKVRCIHCGQSFAIPGDIEVVPPCELCE--GVLKPEVVFFGEMPFVFDQA
SSLLARSEALVVAGSSLVVNTGMRLVTLAYKRRIPIVIINRGPTKADRMATVRIEGGTSETLALVVEGLRS--------
>tr|M5BAS7|M5BAS7_9MICO NAD-dependant protein deacetylase OS=Clavibacter michiganensis subsp. nebraskensis NCPPB 2581 GN=CMN_01690 PE=4 SV=1
-----------------------------------ELMRGRRTAVLTGAGLSTDSGIPDYRGEGAP-K-RNP---MTFQQFRSGDDFRRRYWA--GGHLG
WKAARPNDGHAALADLE-AAGVVGGLVTQNVDGLHERAGSRRVVDLHGSLDRVLCLDCGQTYALDQQVHDIPVCSVCG--GMLKPDVVFFGELPTRFRDA
GAIVSDADVLLIAGSSLAVNSGIRLLEIARRSRMPIVILNRGTTKGDTRATVRLEGGTSETLRAIATELAS--------
>tr|A0A0Q4EYU4|A0A0Q4EYU4_9MICO NAD-dependent deacetylase OS=Agreia sp. Leaf210 GN=ASE64_13690 PE=4 SV=1
-----------------------------------AALAGRRIVVLTGAGMSTDSGIPDYRGEGAP-K-RNP---MTFDQFRESHDYRRRYWA--GSHLG
WKAARPNAGHRVLAALE-DAGVVSGVITQNVDGLHARAGSTHLVDLHGSMDRVLCLNCGQAFAVDEDVTDVPACSVCQ--GMLKPDVVFFGEFPTRFQEA
SALVAGAEAILIAGSSLVVNSGIRLLEQARRRRLPIVIVNRGATKGDSRATVKLDAGATETLTELSRHLLSAKG-----
>tr|U3P8Y9|U3P8Y9_LEIXC Uncharacterized protein OS=Leifsonia xyli subsp. cynodontis DSM 46306 GN=O159_13000 PE=4 SV=1
-----------------------------------EVLSDRRFAVLTGAGVSTDSGIPDYRGEGAP-K-RAP---ITFQQFLADDRHRKRYWV--GSHLR
YRAARPNDGHRALAALE-DGGAATGVVTQNVDGLHKQAGSRRVVDLHGSVDRVLCLVCGQLFALDAIVTDVPDCTVCG--GRLKPDVVFFGEFPAKYREA
SALVRSADALVIAGSSLAVNSGIRLLEEARRRRLPIVIVNRGQTKGDARATVKLNAGTTETLTQLFRRLV---------
>tr|C0W513|C0W513_9ACTO Transcriptional regulator, Sir2 family OS=Actinomyces urogenitalis DSM 15434 GN=HMPREF0058_0957 PE=4 SV=1
-----------------------------------ALMAGRRTLAVTGAGMSTDAGIPDYRGLG---TPVEP---VDFQQFVSDPVWYRWVWA--CNHAT
WQPLRPTPGHRALARLE-EAGYLTGVATQNVDRLHSRAGQSTVWELHGAYDRVVCLECGRVLTYPRAAAETVTCSKCS--GLLKPDIVFFGESPPAMEKA
MQAAGECDVVIAAGTSLAVLTGLWIVRQAVAKGADLVVINRGPTAADELATIRVEGGTSQVLAAVADRLAR--------
>tr|N6X631|N6X631_9ACTO Sir2 family transcriptional regulator OS=Actinomyces cardiffensis F0333 GN=HMPREF9004_0060 PE=4 SV=1
-----------------------------------EAVRKGDVLVVSGAGMSTDSGLPDYRGMG---TPKAP---IDFDMFVSDPVWYRWLWY--RNEAT
WRALEPTLGHLALAALE-QEGLLLGVATQNIDRLDARAGVVSLWELHGRYDTVVCLQCGRAMLIEEEAAEAARCEHCA--GPLKPGIVMFGESPQVFTRA
LRAARAARLVIVAGTSLAVSTGMWVVQEAIQSGAMLAVINRGPTQADRFADLRIEDGTSKILKEVASRCL---------
>tr|A0A0E9ECG8|A0A0E9ECG8_CHLTH NAD-dependent deacetylase OS=Chlamydia trachomatis GN=cobB_1 PE=4 SV=1
-----------------------------------DIACGGRILAVTGAGMSTDSSLPDYRGTG---TPTTP---VDVDMFTSDPVWYRWLWY--RNEAT
WKNCQPNDGHRALATME-ASGHLLGISTQNVDRLDARAGTRNVWELHGRYDTVECLSCGSVTPLVEDLAEPAYCERCG--GMLKPSIVMFGEGPEAFGPS
LDMAASCNVVLVAGTSLAVSTGLWVVHEAMRAGASLIVVNRGATAVDRFADVRIEGGTSEVLPQIATALAG--------
>tr|F9ECR0|F9ECR0_9ACTO NAD-dependent deacetylase OS=Actinomyces sp. oral taxon 448 str. F0400 GN=HMPREF9062_0232 PE=4 SV=1
-----------------------------------RLMAGRRTLAVTGAGISTDAGIPDYRGVG---TPVDP---VDYDQFVSDPVWYRWVWA--RNHAT
WRPLSPTPGHTALARLE-EAGLVTGVATQNVDRLHSRAGQRTVWELHGAYDRVVCLRCGRVTPYPRASAEAVVCEACG--GLLKPDIVFFGESPAAMGEA
MEAAGACDVVLVAGTSLAVLTGLWIVRQALAHGAELIVINRGPTAVDELAGVHVHSGTSQALAPIAQALT---------
>tr|A0A0M4H773|A0A0M4H773_9ACTO NAD-dependent deacetylase OS=Actinomyces sp. oral taxon 414 GN=AM609_14855 PE=4 SV=1
-----------------------------------EVMAGRRTLAVTGAGISTDSGIPDYRGVG---TPIEP---VDFQQFTSDPVWYRWVWA--RNQAT
WRGLAPTPGHLALARLE-EAGLLSGVATQNVDRLHSRAGQATVWELHGAYDRVVCLTCGRMVGFPRAAAEAVTCEVCD--GLLKPDIVFFGESPPAMEAA
MRAAGECDAVLVAGTSLAVLTGLWIVRQAMAHGAEVLVINRGPTAVDELADVRVGGGTSEVLSALAGELLGGE------
>tr|E6LZY5|E6LZY5_9ACTO Transcriptional regulator, Sir2 family OS=Mobiluncus curtisii ATCC 51333 GN=HMPREF0388_1848 PE=4 SV=1
-----------------------------------GWMRGKKTVLVTGAGMSTDTGIPDYRGKG---TEIPS---VEYDQFVSDPVWQRWVWA--RNHQT
WQSLDPAPAHLAQARLE-RAGLLTGIATQNVDGLDLKAGCQEVYEMHGSFARVECVDCGEIIPYPLKAAETVPCERCG--GLLKPAVVFFGQLPAVMSRA
YAAAAAADVVLVVGSSLVVGTASYVMQAGLAKGAPLAIINRGRTMYDRAADLRIESGASPCLTALADLLGA--------
>tr|E0QMD5|E0QMD5_9ACTO Transcriptional regulator, Sir2 family OS=Mobiluncus mulieris ATCC 35239 GN=npdA PE=4 SV=1
-----------------------------------EWMRGRKTVLVTGAGMSTDTGIPDYRGQG---TTIPS---VEYDQFVSDPVWQRWVWA--RNHQT
WQKLDPAPAHLAQARLE-RAGLLTGIATQNVDGLDFKGGCKTVFEMHGTFLKVECVDCGAVTDYPLEAALTVPCETCG--GLLKPAVVFFGQLPETMNRA
RAAAAEADVVLVVGSSLVVGTASFVMQAGLIYGAPLVIINRGRTQYDHMADLRIEGGASECLTRLADLLGA--------
>tr|J0NIR4|J0NIR4_9ACTO Transcriptional regulator, Sir2 family OS=Actinomyces massiliensis F0489 GN=HMPREF1318_2209 PE=4 SV=1
-----------------------------------ALMAGRRTLAVTGAGISTDAGIPDYRGMG---TPVEP---VDYEQFVTDPVWYRWLWA--RNHAT
WRPLEPTPGHAALARLE-EAGLVTGVATQNVDRLHSRADQRTVWELHGAYDRVVCLTCGRIVSYPRDAARPVTCEACG--GLLKPDIVFFGEGPAAMSEA
MDAAGHCDVVLVAGTSLAVLTGLWIVRQAIAHGAELVVINRGPTAVDEMADVRVQGGTSQVLEPLANALGA--------
>tr|W1TK36|W1TK36_9ACTO NAD-dependent deacetylase 1 OS=Varibaculum cambriense DORA_20 GN=Q618_VCMC00003G0264 PE=4 SV=1
-----------------------------------DLMAGKKTIVVAGAGMSTDAGIPDYRGTG---SGMPT---VDMDQFLGELYWQKWVWR--RNQET
WKRLQPTPGHQALARLE-EAGLINCIATQNVDGLDRKAGCKNVQLLHGSFEEVQCLGCGAVFSVKDQAARXXXCPRCG--GTIKPGIVFFGESPGAMDRS
FAAAREADVVLAVGTSLAVLTGLWVLREAWGTGAKVAVINRGPTAADSLADVRVSGGASQVLTQVAEILLD--------
>tr|E4WJ88|E4WJ88_RHOE1 NAD-dependent protein deacetylase OS=Rhodococcus equi (strain 103S) GN=cobB PE=3 SV=1
-----------------------------------ELLHGRRVCVLTGAGISTDSGIPDYRGPDSP--PRNP---MTYQQFVGDPSFRRHYWA--RNHLG
WRAARPNTGHRAVAALE-RAGVVHGVITQNVDLLHTKAGTRQVIDLHGSYAQVRCLDCGAQTSFAEVIETMVDCEQCG--GTLKPDIVYFGESPKRVTAA
FEMVAGADALLVAGSSLTVMSGLRFVRRAARDGLPIVIVNRGATRGDEFATLKIEDGCSDVLESLVSALPG--------
>tr|I0WLN1|I0WLN1_9NOCA NAD-dependent protein deacetylase OS=Rhodococcus imtechensis RKJ300 = JCM 13270 GN=cobB PE=3 SV=1
-----------------------------------DVLGGRRLCVITGAGISTDSGIPDYRGPESP--PRNP---MTYQQFTGDPDFRRHYWA--RNHLG
WRAARPNTGHRALAGLE-RAGVARAVITQNVDLLHTKAGSRRVIDLHGTYAQVRCLACDALISFAEVITSMVDCEACG--GLLKPDIVYFGESPKRVAAA
YDVVDEAEALLVAGSSLTVMSGLRFVRHAAKRGIPIVIVNRGTTRGDEFATLTLHAGCSEALTALLDASSALPA-----
>tr|M2VDB8|M2VDB8_9NOCA NAD-dependent protein deacetylase OS=Rhodococcus triatomae BKS 15-14 GN=cobB PE=3 SV=1
-----------------------------------ALVHGRSVIALTGAGMSTDSGIPDYRGPDSP--PRNP---MTYQQFMGDAAFRRHYWA--RNHLG
WRAARPNTGHRALAALE-RAGTVRGVLTQNVDLLHTKAGSRSVIDLHGSYMQVRCMACEHRTSFAEVIEDVVDCERCG--GTLKPDIVYFGESPRRVDAA
YAMVEAADVLLVLGSSLTVQSGLRFVRHAAKRGMPVAIVNRGATRGDDYAELKLHAGCSETLTALAGSA----------
>tr|A0A0K2YCT5|A0A0K2YCT5_9NOCA NAD-dependent protein deacetylase OS=Rhodococcus sp. RD6.2 GN=cobB PE=3 SV=1
-----------------------------------ALVSRRSVVALTGAGMSTDSGIPDYRGPDSP--PRNP---MTYQQFMGDADFRRHYWA--RNHLG
WRATRPNAGHRALAALE-RSGTVRGVLTQNVDLLHTKAGSRAVIDLHGSYLQVRCMGCERRTSFAEVIEDVVDCEDCG--GILKPDIVYFGESPRRVDAA
FAMVESADVLLVLGSSLTVMSGLRFVRRAAKLGIPVAVVNRGATRGDDYATLKLDAGCSEVLLDVVRSLGHQAL-----
>tr|J7LD16|J7LD16_NOCAA NAD-dependent protein deacetylase OS=Nocardiopsis alba (strain ATCC BAA-2165 / BE74) GN=cobB PE=3 SV=1
-----------------------------------EVLGAGPTAVLTGAGISTDSGIPDYRGPDSP--PRRP---MTYQEFVGDAAFRRHYWA--RNHIG
LRRTRPNDGHLALAELQ-RAGAVGGIITQNVDTLHDAAGSSPVIDLHGRHDRVVCLDCRTVSDFADVLARVADCADCG--GTLKPDIVYFGENPKRVLEA
YAMVEAARALLVVGSSLTVFSGRRFVKRAVELGRPVVILNRGETRCDDLATLTVDQGCSEVLRALAEARRP--------
>tr|W6K3V0|W6K3V0_9MICO NAD-dependent deacetylase 1 OS=Tetrasphaera australiensis Ben110 GN=cobB PE=4 SV=1
------------------------------------LLEDRPALVLSGAGLSTDSGIPDYRGPDGT-RRVTP---MSHGEFVTSPVGRQRYWA--RSYAG
WEAARPNDGHRAITTLQ-QAGRVGAIISQNVDGLHQAAGARDVIDLHGRLAEVVCLTCDARLEFARVLDDAPRCPLCRG-DALKPDVVFFGGSPKRVERC
FALTDQARALLVVGSSLMVMSGLRFVKRAAAHGIPIAVLTKGPTRGDDLATLKIDAPITPVLSRLAGAVRPGAA-----
>tr|A0A0M2MT35|A0A0M2MT35_9ACTN NAD-dependent protein deacetylase OS=Streptomyces sp. MUSC136T GN=cobB PE=3 SV=1
-----------------------------------GQLAAGGVAVLTGAGISTESGIPDYRGASGRHRRHSP---MTYQDFVADEENRRRYWA--RGYVG
RRGARPNAGHHAVQALR-ARGYVDAVITQNVDGLHQAAGTTDAVALHGSLDRVVCLGCGTISPLLAELPEVVPCGRCG--GVLKPYVVFFGENPARTRRC
FELIDAAGSLLVLGSSLAVLSGLRFVRRAAKDGKPVSIINLGPTRGDDLAHAHAALPLGQALTELTERLGIA-------
>tr|W7STD9|W7STD9_9PSEU NAD-dependent protein deacetylase OS=Kutzneria sp. 744 GN=cobB PE=3 SV=1
-----------------------------------DVVGRGRVAVLSGAGISTESGIPDYRGDGGSLRRHTP---MTYDDFVATEHGRRRYWA--RSHVG
WRRAAPNDGHRAVAELQ-KRGLLTGVITQNVDGLHQAGGATDVIELHGSLDRVICLGCRETSAFGGELDELVDCGGCEQ-GVLKPDVVFFGENPRRVEQC
YQLVDDSDALLVLGSSLTVMSGLRFVRHAARAGKPVLIINKGRTRGDKEATVRVDRPLGQALTELVGSV----------
>tr|A0A0M8WMJ0|A0A0M8WMJ0_9NOCA NAD-dependent protein deacetylase OS=Nocardia sp. NRRL S-836 GN=cobB PE=3 SV=1
-----------------------------------PLVESGGVLVLSGAGLSTESGIPDYRGEGGSLRRHTP---MTYEEFTTSAAGRQRYWA--RSHVG
WRRAHPNAGHHAVTRLG---SRLCGVITQNVDGLHQAAGTHDVVELHGGLDRVICLNCGLVSPFAAFLPEVVDCLACG--GVLKPDVVFFGENPRRVEQC
YDLVDNAKSLLVLGSSLTVMSGLRFVRRAAAAGLPVAIINRGETRGDQFAGVRVDLPLGQSLTELADVVLRHGN-----
>tr|A0A0F0GS96|A0A0F0GS96_NOCAE NAD-dependent protein deacetylase OS=Lechevalieria aerocolonigenes GN=cobB PE=3 SV=1
-----------------------------------PIVADGGVLVLSGAGLSTESGIPDYRGEGGSLRKHTP---MTYEEFTTSSAGRQRYWA--RSHVG
WRRAHPNAGHHAVTRLD---AKLSGVITQNVDGLHQAAGSPDVVELHGGLDRVICLDCGVLSPFAAFLPEVVGCDECG--GVLKPDVVFFGENPRRVEQC
YELVGNARSLLVLGSSLTVMSGLRFVRRAADSGIPVVIINRGETRGDQYASHRVDLPLGPTLTELADLVLR--------
>tr|W7IS47|W7IS47_9PSEU NAD-dependent protein deacetylase OS=Actinokineospora spheciospongiae GN=cobB PE=3 SV=1
-----------------------------------ELVDRGGVLVLSGAGLSTESGIPDYRGAAGSLRKHTP---MTYGEFVADPDARRRYWA--RSHVG
WRRAAPNAGHRAVTALH-ARGHLTGVITQNVDGLHQAAGTPDVVELHGGLDRVVCLSCREPTPFSADLDDVVACRTCD--GVLKPDVVFFGENPRRVDLC
NALVDAAASVLVLGSSLTVMSGLRFIRRAATTATPVAIINQGETRGDQHATHRVDLPLGHALTELRSRLSA--------
>tr|D2Q1M5|D2Q1M5_KRIFD NAD-dependent protein deacetylase OS=Kribbella flavida (strain DSM 17836 / JCM 10339 / NBRC 14399) GN=cobB PE=3 SV=1
-----------------------------------DVVAAGGVVVLSGAGISTESGIPDYRGASGSLRTHTP---MTYGDFVGSEAGRRRYWA--RSHLG
WRRADPNAGHRAVATLQ-ARGYLTAVITQNVDGLHQSAGARDVIELHGNLDRVICLDCHETSPFEGELPDLVPCRRCGS-PLLKPDVVFFGENPKRVERC
YRLIDEAEAMLVLGSSLTVMSGFRFVRYAAKAGKPVLIINQGITRGDPHATHRVNLPLGHALTTLTSALA---------
>tr|A0A066TVR6|A0A066TVR6_9PSEU NAD-dependent protein deacetylase OS=Amycolatopsis rifamycinica GN=cobB PE=3 SV=1
-----------------------------------GVVARGRVAVLSGAGLSTESGIPDYRGESGSLRRHTP---MTYDEFVTSAEGRQRYWA--RSHLG
WRRAHPNDGHRAVTALR-DGGYVSGVITQNVDGLHQAAGTADAVELHGSLDRVICLDCRRTSPFTGELPATVPCALCD--GVLKPDVVFFGENPRRVEQC
YRLVDDAEALLVLGSSLTVMSGLRFVRHAARAGKPVVIVNRGETRGDRYASVRVDRPLGPALTELVSRLGEGRG-----
>tr|M0L820|M0L820_9EURY Silent information regulator protein Sir2 OS=Halobiforma lacisalsi AJ5 GN=C445_18341 PE=4 SV=1
-----------------------------------AEIRDATVVALTGAGISAPSGVPTFRGEDGVWH-FDE---GQFTRFRSDPE---GFWA--DRVAL
QREYEPNAAHEALAAMG-RDGYLDAVLTQNTDGLHRDAGEPPILELHGNARRVRCTDCGRRRD---AAE-LPPTCDCG--GIYKPDVVLFGEQPGVVQRA
RTLTRDSDVFLAIGSSLVVEPAASFPREAGATGATVGVVNLESTPVDGAADVVYRDDVTEALPRLRSLLERGAD-----
>tr|L0AJB8|L0AJB8_NATGS NAD-dependent protein deacetylase, SIR2 family OS=Natronobacterium gregoryi (strain ATCC 43098 / CCM 3738 / NCIMB 2189 / SP2) G
-----------------------------------AEIRDATVVALTGAGISAPSGVPTFRGDDGVWH-FDE---GQFTRFRSDPA---GFWE--DRIEL
QRDYEPNAAHEALTEME-QEGYLDAILTQNTDGLHGDAADATILELHGNARQVRCIDCGRRRD---AAK-RPPTCDCD--GIYKPDVVLFGEQPGAIQRA
RTLARESDVFLAIGSSLVVEPAASLPHLAVSSDATVGVVNLESTPVDDAADVVCRADVTEAVPRLQSSL----------
>tr|L9X425|L9X425_9EURY Silent information regulator protein Sir2 OS=Natronococcus amylolyticus DSM 10524 GN=C491_12987 PE=4 SV=1
-----------------------------------EAITADTAAVLTGAGISAPSGIPTFRGDDGVWH-FDE---GQFTRFRSDPE---GFWA--DRLEL
QEGYEPNAGHEALAALE-RDGYLDAVCTQNTDGLHRDAGEGSVLELHGNARRVRCTDCGRRRE---AAD-LPPTCDCG--GVYKPDVVLFGEQPGVIQRA
QSLARESDVFLAIGSSLVVEPAASLPRRAASSGATVGVINLESTPCDAAVDVVRREDVTEVLPRLRELVES--------
>tr|L9XB06|L9XB06_9EURY Silent information regulator protein Sir2 OS=Natronococcus jeotgali DSM 18795 GN=C492_12814 PE=4 SV=1
-----------------------------------EAINADTAAVLTGAGVSAPSGIPTFRGDDGVWR-FDE---GQFTRFRSDPA---GFWV--DRLEL
QEGYEPNPAHEALAALE-RDGHLEAVLTQNTDGLHADATADSVLELHGNARRVRCADCGRRRP---AAD-LPPTCDCG--GVYKPDVVLFGGQPGVIQRA
RSLARESDAFLAIGSSLAVEPAASLPRRASSSGATVGIVNLESTPCDDAADVVRREGVTEALPRLRELVVEG-------
>tr|M0MLD7|M0MLD7_9EURY Silent information regulator protein Sir2 OS=Halobiforma nitratireducens JCM 10879 GN=C446_01528 PE=4 SV=1
-----------------------------------AEIRDATVVALTGAGISAPSGVPTFRGDDGVWH-FDE---GQFTRFRSDPA---GFWE--DRIEL
QRDYEPNAGHEALAELG-RDGYLDAVLTQNTDGLHGDA-ETPILELHGNARRVRCTDCGTRRE---AAD-LPPTCDCG--GIYKPDVVLFGEQSGVIQRA
RSLTAESDIFLGIGSSLVVEPAASLPREAATTGATIGIVNLESTPVDGVADAVSHVDVTDALPRLQSLLADRDR-----
>tr|A0A063ZSY0|A0A063ZSY0_9EURY NAD-dependent protein deacetylase OS=Halostagnicola sp. A56 GN=EL22_20995 PE=4 SV=1
-----------------------------------DEIRAETVVAFTGAGISAPSGVPTFRGEDGVWR-FDE---GQFTRFRRDPE---GFWA--DRLEL
HEDYEPNVAHEALASLG-AADHLDAIITQNTDGLHERTAETTLLELHGNAHRAVCAMCSRRID---VVA-LPPTCDCG--GTYKPDVVLFGEQPGTLQRA
RSLARESDVFLAIGSSLVVEPAASLPRAASSTGATLGIVNLESTPCDDATEIVHREDVTAALPELEALLLE--------
>tr|M0C9E5|M0C9E5_9EURY Silent information regulator protein Sir2 OS=Haloterrigena salina JCM 13891 GN=C477_10598 PE=4 SV=1
-----------------------------------DEISADTVVAFTGAGISAPSGVPTFRGDDGVWK-FDE---GQFTRFRSDPE---GFWD--DRVDL
QREYQPNAAHDALAAIG-RDGHLEAILTQNTDGLHAKADDTTLLELHGNARRVRCTDCGRRRD---AAE-LPPTCDCG--GVFKPDVVLFGEQPGVIQRA
RSLARESDVFLAIGSSLVVEPAASLPRQAASTGATVGIVNLESTPVDDAADVVRREDVTEVLPRLRELLETP-------
>tr|A4X7H5|A4X7H5_SALTO NAD-dependent protein deacetylase OS=Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440) GN=cobB PE=3 SV=1
-----------------------------------GLVSGGGVVVLSGAGLSTESGIPDYRGASGAARRHSP---MTYQVFVGDPLARRRYWA--RSYLG
WRGAVPNAGHRAVARLQ-DAGLVDGVVTQNVDGLHTAAGSGGVVELHGRLDEVVCLGCGVGMSFEADLADTVDCARCDA-GTLKPDVVFFGESPPRVARC
FAMVESARLLLVLGSSLTVLSGRRFVVRAASLGIPVAIVNQGATRGDAYATVTVDAPLGRVLPVLADRFGAVRD-----
>tr|I0L4J1|I0L4J1_9ACTN NAD-dependent protein deacetylase OS=Micromonospora lupini str. Lupac 08 GN=npdA PE=3 SV=1
-----------------------------------SLVAGGQVVVLSGAGLSTESGIPDYRGPSGVARRHTP---MTFQAFTRDPLARRRYWA--RSHLG
WRRAAPNDGHRAVARLQ-RAGLVDAVITQNVDGLHGAAGSDRVVELHGRLDEVVCLDCGNLTSFVADLPDPVDCGICGT-GMLKPDVVFFGETPPRVARC
FALVEQARAVVVLGSSLTVMSGRRFVIRAAKRGIAVAIVNQGPTRGDGYATVCVDAPLGTVLPALAERVAGGAA-----
>tr|A8M397|A8M397_SALAI Silent information regulator protein Sir2 OS=Salinispora arenicola (strain CNS-205) GN=Sare_2516 PE=4 SV=1
-----------------------------------GLVSGGGVVVLSGAGLSTESGIPDYRGPSGVARRGAP---MTYQVFTQDPLARRRYWA--RSHLG
WSRAVPNAGHRAVARLQ-HAGLVDGVITQNVDGLHTEAGSGGVVELHGRLDEVVCLGCGAVGSFEADLADTVDCDRCGT-GILKPDVVFFGESPARVSRC
FALVESARLLLVLGSSLTVMSGRRFVLRAARLGIPVAIVNQGATRGDAYAAVTVDAPLGRLLPALADRVGAVAV-----
>tr|D9TDE3|D9TDE3_MICAI NAD-dependent protein deacetylase OS=Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 94
-----------------------------------RLVAAGDVVVLSGAGLSTESGIPDYRGPSGAARRHTP---MTYQEFTRDPLARRRYWA--RSHLG
WQRAAPNDGHRAVARLQ-DAGLLGGIITQNVDGLHTAAGATGVIELHGRLDEVTCLDCGNATGFDADLPDAVDCGVCGT-GMLKPDVVFFGETPARVADC
FALVERARALLVLGSSLTVMSGRRFVLRAARHGIPVAIVNQGVTRGDGYAALRLDAPLGATLCALADRVAAAPA-----
>tr|D2B5T1|D2B5T1_STRRD NAD-dependent protein deacetylase OS=Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100) GN=cobB PE=3
-----------------------------------KLLAAGEVVVLSGAGLSTESGIPDYRGPSGASRRHTP---MTYQTFVGDPAARRRYWA--RSYVG
WRRATPNSGHHAVAHLQ-RLGLVAGVVTQNVDGLHQAGGARAVVELHGSLHHVICLDCGDSSPFGAELGDVVGCRACDG-GVLKPDVVFFGETPARVREC
FALVERARLLLVLGSSLTVMSGRRFVLHAAKLGIPVAIVNQGPTRGDKYAALAVDAPLGTALPELVRLVDTRAA-----
>tr|K6WKL7|K6WKL7_9MICO NAD-dependent deacetylase OS=Kineosphaera limosa NBRC 100340 GN=cobB PE=4 SV=1
-----------------------------------ELVNGGGVVALTGAGMSTESGIPDYRGPDGA-RRVTP---MTIDQFRDEYGA-RHYWS--RAYVG
WDAARPNVGHVALAELE-RRGLVDAVITQNVDGLHQEAGSGTVLELHGTLTTVVCLDCSAVFRFAQELPGVAACEDCGG-DQLKPDVVFFGESHRVVARC
FERIESARSLLVLGSSLAVMSGLRFVRRAARMGLPVAIVTNGPTRGDELATLRLTGPLGEVLPALATAADRTT------
>tr|A0A0G3HBR6|A0A0G3HBR6_9CORY NAD-dependent protein deacetylase OS=Corynebacterium uterequi GN=cobB1 PE=3 SV=1
-----------------------------------EQFRRGDVLVLTGAGVSTESGIPDYRGPAGSLTRGRP---MTYQEFLVDHAALRRYWA--RSYVG
WTAARPNRAHYGLVEVE-RAGLLAGLITQNVDGLHHAAGQKRVVALHGDLATVVCLDCEAKEPYLQDLPEMVGCRRCGS-VRLKPDVVYFGEPPRRKDAM
SAMLGAAKAVVVLGSSLAVMSGFRLVIAAQRTGIPVSVINGGPGRADERVDVLWRTNVGDAVDALLDELEL--------
>tr|W9GAE9|W9GAE9_9MICO NAD-dependent protein deacetylase 1 OS=Intrasporangium oryzae NRRL B-24470 GN=N865_01700 PE=4 SV=1
-----------------------------------DLVSGGGVVVLSGAGLSTESGIPDYRGPDGT-RRVEP---MTYGEFAGSGEARRRYWA--RSYIG
WQAASPNRGHHHVTRLQ-QHGYVGPIITQNVDGLHQASGAEDVVELHGSLDRAVCLTCGEVTSFMDVLADTPRCLVCGN-DTVKPDVVFFGESPKVVERC
FELVDTAGAVLVLGSSLSVMSGYRFVRRAHQRGIPVAIVTRSATRGDAEATIRLHRPLGDTLDRLAEALHL--------
>tr|A0A0I9VZY9|A0A0I9VZY9_9MICO Uncharacterized protein OS=Dermacoccus sp. PE3 GN=AA983_06350 PE=4 SV=1
-----------------------------------EFVAQGDLFVLTGAGLSTESGIPDYRKPDGTR--TVP---MTFQQFLSGDDARRRYWV--RSAVG
WEAARPNGGHHAVAALQ-RAGLVQHLVTQNVDGLHAASGAD-ALELHGSLSSVQCVECGSRSDLPREVARLVACPHCDS-LVVKPDVVMFGESPTTVEHC
YAQLELSRAVLVLGSSLKVMSGFRFVSAALKAGKPVALVGLGSMRGSERADLVLHEPLGATLTATCERLGLQVQ-----
>tr|E6S7N9|E6S7N9_INTC7 Silent information regulator protein Sir2 OS=Intrasporangium calvum (strain ATCC 23552 / DSM 43043 / JCM 3097 / NBRC 12989 / 7 
-----------------------------------DLVSGGGVLVLSGAGMSTDSGIPDYRGPDGT-RRVEP---MTLGEFAGSSEARRRYWA--RSYIG
WQQARPNSGHERVTALQ-RDGYVGPIITQNVDGLHQQSGARDVVELHGSLDRAVCLTCGEVTSFREVVADPPLCLVCGR-DTVKPDVVFFGESPKLVERC
FGLVDAAGAVLVLGSSLSVMSGYRFVRHAARIGVPVAIVTRSATRGDGDATIRLHAPLASTLDALGVALRH--------
>tr|W9GE42|W9GE42_9MICO NAD-dependent protein deacetylase OS=Intrasporangium chromatireducens Q5-1 GN=cobB PE=3 SV=1
-----------------------------------DLVSAGGLVVLSGAGISTDSGIPDYRGPDGT-RRVEP---MTYGQFTGSSEARRRYWA--RSYIG
WQAARPNSNHRHVSALE-QAGYVDAVITQNVDGLHQAAGSQDVLELHGSLDRAVCLTCGEVASFMEVLADAPRCLVCGH-DSVKPDVVFFGESPKLVDES
FRLVESAGALLVLGSSLAVMSGYRFVRRARQVGVPVAIVTQSATRGDADASIRIHAPLAPTLDALGAALEP--------
>tr|A0A0A0J1A5|A0A0A0J1A5_9MICO NAD-dependent deacetylase OS=Knoellia flava TL1 GN=N798_14100 PE=4 SV=1
-----------------------------------LLRAHGPALVLTGAGMSTESGIPDYRGPDGN-RRVTP---MSHQEFTATSEARQRYWA--RSFIG
WQAAEPNAGHLAVTDLQ-AAGVFGPVITQNVDGLHQEAGTREVTELHGSLAEVVCLTCGERVDFASVLADAPRCLVCGD-DTLKPDVVFFGGAPRRVDLC
FSLTDEAPVLVVLGSSLKVMSGYRFVRRAAAHGIPVVVITRGPTRGDAETTHRIDASLGVTLSALAREVGERAD-----
>tr|A0A0Q9ML29|A0A0Q9ML29_9MICO NAD-dependent protein deacetylase 1 OS=Tetrasphaera sp. Soil756 GN=ASG78_09525 PE=4 SV=1
-----------------------------------MLHDHPGTLVLTGAGMSTDSGIPDYRGRDGT-RRVTP---MQHGEFCASTENRRRYWA--RSFVG
WQRAEPNAGHRAVAALQ-RSGVLGPVVTQNVDGLHQVAGSRDVTELHGTLAEVVCLTCGDRSPFEAVLPDLAACPVCGA-DTLKPDVVFFGGSPRRVEHV
FALTDAAPALLVLGSSLAVMSGLRFVRHAARRGIPVVGVTRGPTRGDEHMSLRVDADLAPTLQRVLAARGRAA------
>tr|A0A0A0J1J0|A0A0A0J1J0_9MICO NAD-dependent deacetylase OS=Knoellia sinensis KCTC 19936 GN=N802_07000 PE=4 SV=1
-----------------------------------LLRHRGPALVLTGAGMSTESGIPDYRGPDGS-RRVTP---MSHQEFTASGDNRQRYWA--RSFIG
WQAAEPNVGHRAVTALQ-RAGAFGHVITQNVDGLHQRAGTGDVTELHGSLEEVVCLTCGERADFATVLPDAPRCLVCRA-DTLKPDVVFFGGSPKRVDLC
FALTDAAPILVVLGSSLKVMSGYRFVRRAAAHGIPIVVITKGPTRGDAETTHRIDAPLGVTLSALAADFSHAQT-----
>tr|A0A0A0JWE7|A0A0A0JWE7_9MICO NAD-dependent deacetylase OS=Knoellia aerolata DSM 18566 GN=N801_17830 PE=4 SV=1
-----------------------------------LLRETGPALVLTGAGLSTESGIPDYRGPDGN-RRVTP---MSHQEFTATSEARQRYWA--RSFIG
WQAAEPNDGHLAVTDLQ-RAGALGAVITQNVDGLHQDAGTREVIELHGSLAEVVCLTCEGRVDFASVLADTPRCLACDA-DTLKPDVVFFGGAPKRVEQC
YALTEAASALVVLGSSLKVMSGYRFVRRAAARGIPVVVITRGPTRGDAETTHRIDAPLGVTLAALTRAVGAQVA-----
>tr|A3TJI2|A3TJI2_9MICO Putative SIR2-like regulatory protein OS=Janibacter sp. HTCC2649 GN=JNB_00175 PE=4 SV=1
-----------------------------------LLGQRGPALVLTGAGISTESGIPDYRGPDGN-RRVTP---MSQQEFVATSGARQRYWA--RSFIG
WQVAEPNAGHRAVTGLQ-RAGAFGTVITQNVDGLHQDAGTRDVIELHGSLAEVECLTCGERVDFASVLADAPRCLVCRA-DTLKPDVVFFGGSPKRVEQC
FALTEAAPALVVLGSSLKVMSGYRFVRRAAAHGIPVVVVTKGPTRADAETTHRIDAPLGVTLSALADEFAVRVN-----
>tr|A0A0Q9KW95|A0A0Q9KW95_9MICO NAD-dependent protein deacetylase 1 OS=Knoellia sp. Soil729 GN=ASG74_14830 PE=4 SV=1
-----------------------------------LLRERGPALVLTGAGISTESGIPDYRGPDGN-RRVTP---MSHQEFTATSAARQRYWA--RSFIG
WQAAEPNAGHFAVAALQ-RAGAFGPIITQNVDGLHQSAGATDVIELHGNLAEVVCLTCEERVDFASVLDDAPRCLVCRE-DTLKPDVVFFGGSPKRVEQC
FALTDAAPVLVVLGSSLKVMSGYRFVRRAAAHGIPVVVVTKGPTRAEAETTHRIDAPLGVTLSALAEVTLPRVM-----
>tr|A0A0A0JFG7|A0A0A0JFG7_9MICO NAD-dependent deacetylase OS=Knoellia subterranea KCTC 19937 GN=N803_09130 PE=4 SV=1
-----------------------------------LLRERGPALVLTGAGISTESGIPDYRGPDGN-RRVTP---MSHQEFTATSAARQRYWA--RSFIG
WQAAEPNAGHVAVARLQ-RVGAFGDVITQNVDGLHQQAGASNVIELHGTLSEVECLTCGERTDFAAVLADAPRCLVCGH-DTLKPDVVFFGGSPKRVEAC
FELTDAAPALVVLGSSLKVMSGYRFVRRAAANGIPVVVVTKGPTRGDAETTHRIDAPLGVTLSALADELAPAS------
>tr|A0A077MF15|A0A077MF15_9MICO NAD-dependent protein deacetylase OS=Tetrasphaera jenkinsii Ben 74 GN=npdA PE=3 SV=1
-----------------------------------RFLDHGPPMVLTGAGMSTDSGIPDYRGPDGT-RRVTP---MQHGEFVGSSAARQRYWA--RSFIG
WQAAAPNAGHRALAHLG-TGGLIGPLVTQNVDGLHQRAGSRNVTELHGSLAEVVCLTCGTRESFAEVLADTPRCLVCGH-DTVKPDVVFFGASPARVQRV
YALTDAAPALLVLGSSLMVMSGLRFVKRAAARGIPIAIVTRGATRGDAYAALRLDESLSPLLVAVAGIRGLTQA-----
>tr|N0E6F2|N0E6F2_9MICO NAD-dependent deacetylase 1 OS=Tetrasphaera elongata Lp2 GN=npdA PE=4 SV=1
-----------------------------------VLLRKPGALVLTGAGISTESGIPDYRGPDGK-RRVTP---MEHSEFVGSSGARQRYWA--RSYIG
WAGAEPNDGHRGVAALQ-RSGHLGAIITQNVDGLHQRAGAREVTELHGSLGDAICLDCGAVHDFAEVLADQPTCPRCDS-DKVKPDVVFFGGSPKRVDHC
FALTDAAPALLVLGSSLQVMSGFRFVRRAAARGIPCLAITRGPTRAEDLLAHHLDAPLGETLKALQERLIQ--------
>tr|A0A0Q9TJ74|A0A0Q9TJ74_9MICO NAD-dependent protein deacetylase 1 OS=Terrabacter sp. Soil810 GN=ASG96_14230 PE=4 SV=1
-----------------------------------DLVSGGGVVVLSGAGLSTESGIPDYRGPDGT-RRVEP---MTYGEFAGSSEARRRYWA--RSYIG
WQAAEPNDGHRVVTDLQ-RAGYVGPIITQNVDGLHQASGATDVVELHGSLERAVCLTCGEYATFREVLADAPRCLVCGN-DTVKPDVVFFGESPKVVERC
FSLVDGAGAVLVLGSSLSVMSGYRFVRRAHQRDVPVAIVTRSATRGDAEATLRLHAPLGPTLTELRDALGH--------
>tr|D9VLJ3|D9VLJ3_9ACTN NAD-dependent protein deacetylase OS=Streptomyces sp. C GN=cobB PE=3 SV=1
-----------------------------------DALADGGVLVLTGAGISTESGIPAYRGQGGSLTRHTP---MTYQDFTAGAQARRRYWA--RSHLG
WRRARPNAGHRAVAAFG-RHGLLAGVITQNVDGLHQAAGSDPVVELHGSLARVVCLSCGAAGPFAPDLTDVVPCARCG--GVLKPDVVFFGESPPRVEHC
RALVDAAASLLVLGSSLTVMSGLRFVREAARAGKPVLIVNQDPTRGDRHAAARVALPLGPALTTVAARLDVPVP-----
>tr|C6WFH5|C6WFH5_ACTMD NAD-dependent protein deacetylase OS=Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971) GN=cobB PE=3 
-----------------------------------DLLRPGRALVLSGAGLSTGSGIPDYRGAEGSLRKHTP---MTYQDFTASAEGRRRYWA--RAHVG
WRRAEPNDGHRAVAALQ-RAGLVDAVITQNVDGLHQDGGATDVVELHGSLYRVICLDCGATTDFTADLPAVVDCARCG--GVLKPDVVFFGENPPRVRHC
YDLVDAADTLLVLGSSLTVMSGLRFVRHAAKSGKPVAILNRGVTRGDDRAAVRVDRELGQALGELVDLLGAG-------
>tr|A0A0M8U9V2|A0A0M8U9V2_9ACTN NAD-dependent protein deacetylase OS=Streptomyces sp. H021 GN=cobB PE=3 SV=1
-----------------------------------EALSAGGVLVLSGAGISTESGIPDYRGEGGSLRRHTP---MTYQEFTASARARRRYWA--RSHLG
WRRARPNAGHRAVTAFG-RHGLLSGVITQNVDGLHQAAGSEDVVELHGSLDRVVCLSCGASGSFEPDLTDVVPCAQCG--GVLKPDVVFFGETPPRVERC
RELVDGATSLLVLGSSLTVMSGLRFVRQAAQAGKPVLIVNRDPTRGDRHAVSRLTLPLGTALTDLAARLDVPVD-----
>tr|A0A0N0SCU7|A0A0N0SCU7_9ACTN NAD-dependent protein deacetylase OS=Streptomyces sp. WM6368 GN=cobB PE=3 SV=1
-----------------------------------DALRGGGVLVLSGAGMSTESGIPDYRGKGGSLSRHTP---MTYQEFTASDGTRRRYWA--RSHLG
WRRARPNAGHRAVAAFE-RAGLLTGVITQNVDGLHQAAGSEGVVELHGSLDRVVCLACGAIDSFEPDLTDVAPCARCG--GVLKPDVVFFGESPPRVEHC
RGLVDAATSLLVLGSSLTVMSGLRFVRQAARAGKPVLIVNNDPTRGDPHALTRVALPLGPTLTDVAGRLGVPVA-----
>tr|A0A0F4JIX2|A0A0F4JIX2_9ACTN NAD-dependent protein deacetylase OS=Streptomyces katrae GN=cobB PE=3 SV=1
-----------------------------------DALRAGGVLVLSGAGISTESGIPDYRGEGGSLSRHTP---MTYQEFTASAGARQRYWA--RGHLG
WRRARPNAGHRAVAAFG-RHGLLSGVITQNVDGLHQAAGSEGVVELHGSLERVVCLSCGALSPFEPDLTQVVPCAVCG--GVLKPDVVFFGESPPRVEHC
RELVREAAALLVLGSSLTVMSGLRFVRQAADAGKPVLIVNRDRTRGDLQAVARVALPLGTALTTVAARLGVPVD-----
>tr|S4MR32|S4MR32_9ACTN NAD-dependent protein deacetylase OS=Streptomyces afghaniensis 772 GN=cobB PE=3 SV=1
-----------------------------------DALSTGGVLVLSGAGISTESGIPDYRGEGGSLSRHTP---MTYQDFTAGAQARRRYWA--RSHLG
WRRALPNAGHRAVAAFG-RHGLLSGVITQNVDGLHQVAGSEDVVELHGSLARVVCLACGAFSPFAPDLTDVVPCASCG--GILKPDVVFFGENPPRVEHC
RELVRESASLLVLGSSLTVMSGLRFVRQAAQDGKPVLIVNREPTRGDRHAFTRVSLSLGAALTTVAERLGITVG-----
>tr|A0A0M8VYH3|A0A0M8VYH3_9ACTN NAD-dependent protein deacetylase OS=Streptomyces sp. AS58 GN=cobB PE=3 SV=1
-----------------------------------AALNTGGVLVLSGAGISTESGIPDYRGEGGSLGRHTP---MTYQDFTADPRARRRYWA--RSHLG
WRRARPNAGHRAVAAFA-RHGLLSGVITQNVDGLHQAAGSETVTELHGSLARVVCLSCGAFSPFEPDLTDVMPCAICG--GILKPDVVFFGETPPRVEHC
RELVRGATSLLVLGSSLTVMSGLRFVRQAAQAEKPVLIINRDPTRGDPHAVTRVALTLGAALSTVADRLNIPVD-----
>tr|A0A0M2GKG6|A0A0M2GKG6_9ACTN NAD-dependent protein deacetylase OS=Streptomyces variegatus GN=cobB PE=3 SV=1
-----------------------------------DALSAGGVLVLSGAGISTESGIPDYRGEGGSLSRHTP---MTYQDFVAGAQARRRYWA--RSHLG
WRRARPNAGHRAVAAFG-RHGLLAGVITQNVDGLHQAAGSDDVVELHGNLARVVCLSCGAFSPFDPDLTDVVPCAVCG--GTLKPDVVFFGESPPRVEHC
RELVRGAASLLVLGSSLTVMSGLRFVRQAAQAGKPVLIVNRDQTRGDRHAVTRVSLPLGTALSTVAHRLGIPVD-----
>tr|A0A086MSN1|A0A086MSN1_9ACTN NAD-dependent protein deacetylase OS=Streptomyces mutabilis GN=cobB PE=3 SV=1
-----------------------------------DALGAGGVLVLSGAGISTESGIPDYRGEGGSLSRHTP---MTYQDFTAGAPARRRYWA--RSHLG
WRRARPNAGHRAVAAFG-RRGLLAGVITQNVDGLHQVAGSEDVVELHGSLDRVVCLSCGAFSPFDPDLTDVVPCMICG--GILKPDVVFFGENPPRVEHC
RALVREATSLLVLGSSLTVMSGLRFVRQAAEAGKPVLIVNRDPTRGDRHALARVSVPLGAALTGVADRLGIPVG-----
>tr|F2R8L5|F2R8L5_STRVP NAD-dependent protein deacetylase OS=Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 1309
-----------------------------------DALRAGGVLVLTGAGISTESGIPDYRGAGGSLSRHTP---MTYQEFTADARARRRYWA--RSHLG
WRRARPNTGHRAVAAFG-RHGLLTGVITQNVDGLHQSAGSEGVVELHGSLERVVCLSCGAFSPFAPDLTDVLPCIVCG--GVLKPDVVFFGEAPPRVEHC
RELVDQADSLLVLGSSLTVMSGLRFVRQAAQAGKPVLIVNRDPTRGDRHAVTRVALPLGAALTTAAARLGIPVD-----
>tr|A0A0L0T317|A0A0L0T317_ALLMA Uncharacterized protein OS=Allomyces macrogynus ATCC 38327 GN=AMAG_13638 PE=4 SV=1
-----------------------------------AFICHGKLLVITGAGVSTPSNIPDYRGPKGAYVDYKP---IQYQEFMGRHYNRQRYWA--RSMLG
YGHAQPNTIHHSLAEIE-AKGHLVGVVTQNVDSLHHKAGGRNVIELHGTLARVECQSCGHAIPWVQDVA-YPPCHKCGNKSVLKPAVVFFGENPPVKEQA
AELVGKASGGLVLGSTLTTYSAYRLVRDLHAAGKPVWCINKGPTRADALLTRKIEAPIQEIMADVAEML----------
>tr|A0A0Q4UXX4|A0A0Q4UXX4_9MICO NAD-dependent deacetylase OS=Curtobacterium sp. Leaf261 GN=ASF23_01040 PE=4 SV=1
-----------------------------------DLLRGKRVAVLSGAGLSTDSGIPDYRGAGSV-P-RTP---MTFQEFRSDPAKRQRYWA--GSHLG
WRAAAPNAGHRALATLE-DAGVVSGVVTQNVDGLHLRSGSRRVVEIHGSMDRVVCLDCGQAFSVDEEVADVPSCSVCG--GMLKPDVVFFGEFPAKFREA
VSIVAGADALLVVGSSLVVNSGVRLVDHAARRKKPVAIVNRGATRSDRRAALTLHAGTTETLVTLAERLVP--------
>tr|A0A0Q5RAV0|A0A0Q5RAV0_9MICO NAD-dependent deacetylase OS=Curtobacterium sp. Leaf183 GN=ASG04_11705 PE=4 SV=1
-----------------------------------ELLAGKRIAVLSGAGLSTDSGIPDYRGAGRV-V-RKP---MTFQEFRADPAKRQRYWA--GSHLG
YRAAAPNAGHHALAALE-RAGVVTGIVTQNVDGLHLRAGSRRVVEIHGSTDRALCLTCGQVFAIDEEITDVPACSVCG--GVLKPDVVFFGEFPTKFAES
VSLVADADALLVVGSSLTVNSGVRLVDHAARRKHPVVIVNRGATRSDRRAAVKIDAGTTETLQELADRLVLR-------
>tr|A0A022LYR1|A0A022LYR1_9MICO NAD-dependent deacetylase OS=Curtobacterium flaccumfaciens UCD-AKU GN=H489_0101055 PE=4 SV=1
-----------------------------------ELLAGKRVAVLSGAGLSTDSGIPDYRGAGRV-V-RKP---MTFQEFLADPAKRQRYWA--GSHLG
WRAATPNDGHRALAALE-DAGIVAGVITQNVDGLHLRAGSRRVVEIHGSMDRAVCLRCGQVFSIDEEITEVPACSVCG--GDLKPDVVFFGEFPAKFREA
VSIVADADALLVVGSSLTVNSGVRLVDHAARRKNPVVIVNRGETRSDRRAAVKLDAGTTETLVHLAERLSAAGA-----
>tr|A0A0L0BFD7|A0A0L0BFD7_9MICC NAD-dependent protein deacetylase OS=Arthrobacter sp. RIT-PI-e GN=cobB PE=3 SV=1
-----------------------------------SLLGGLRLAVLTGAGLSTDSGIPDYRGPDSV--PRNP---MTYQQFVGDEALRRRYWA--RNHVG
WRRADPNAGHAAVARLE-QRGLLSGLITQNVDKLHTAAGSIDVIDLHGTFDRVVCLECASVFPYLEDVDDMAPCPVCG--GMLKPDFVYFGENPKRVADA
YAMVDAADGLLVAGSSLTVMSGLRFVRHASKAGKPIVIINRGPTRGDEFATVKIEAGVSEALTYLADHLPDVNT-----
>tr|N1V2Z4|N1V2Z4_9MICC NAD-dependent protein deacetylase OS=Arthrobacter crystallopoietes BAB-32 GN=cobB PE=3 SV=1
-----------------------------------EILSGRPLAVLTGAGLSTDSGIPDYRGPGSV--PRNP---MTYQQFVSDELLRRRYWA--RNHAG
WRRAQPNSGHFALAEIE-RKGVLTGLITQNVDRLHQAAGSRKVIDLHGRFDQVICLDCGTIVDWTADISDVAACEVCG--GMLKPDFVYFGENPKRVAAA
YAMVDAAAALLVAGSSLTVMSGLRFVRHAAKQEKPVVIINRGQTRGDGLAAVKLEAGTSESLQALSAGLPGLAG-----
>tr|A0A0D4BYJ3|A0A0D4BYJ3_9MICC NAD-dependent deacetylase OS=Arthrobacter sp. IHBB 11108 GN=UM93_06135 PE=4 SV=1
-----------------------------------AQLQGRQIALLTGAGLSTDSGIPDYRGPGAP--VRNP---LTYQQFTQDESLRRRYWA--RNQLG
WRHAKPNSGHFAAARLE-ARGLLSGTITQNVDRLHEDAGARNVVDLHGRFDRVICLNCETEFGFVEELDSILACPVCG--GMLKPDFVFFGENPKRVERS
FEILNRAEVLLVAGSSLTVMSGLRFPRRAVKDGKSVVIINRGQTRGDDLATLKIDLGVGAALEYLANELPDLR------
>tr|A0A0N8HXT3|A0A0N8HXT3_9MICC NAD-dependent deacetylase OS=Arthrobacter sp. Edens01 GN=AO716_10995 PE=4 SV=1
-----------------------------------GLLSGRRIALLTGAGLSTDSGIPDYRGPDAP--PRNP---MTYQQFVGDPVMRQRYWA--RNHVG
WHHAVPNAGHEAVVHLE-ERGLLTGVITQNVDRLHSDAGSIRVIDLHGRFDRVVCLSCGSVYTYLEEITDVADCPVCE--GMLKPDFVYFGENPKRVRLA
YAAVDDAGALLVAGSSLTVMSGLRFVRHASKEGKPVVIINRGQTRGDDLADLKIDMGVGTALQYLARNLPDPGP-----
>tr|A0A0Q9R844|A0A0Q9R844_9MICC NAD-dependent deacetylase OS=Arthrobacter sp. Soil782 GN=ASH00_15930 PE=4 SV=1
-----------------------------------DLLAHLRLTVLTGAGLSTDSGIPDYRGPNSV--PRNP---MTYQQFVGDDALRRRYWA--RNHIG
WHRAHPNDGHRALVRME-QRGLLTGLITQNVDRLHSSAGSTKVVDLHGTYDRVVCLSCRTLFSYLEDVDDVAPCPVCG--GMLKPDFVYFGENPRRVDRA
YAMVDDAGALLVAGSSLTVMSGLRFVRHAAKQAKPVVIINRGATRGDDFASLKLELGVSESLAYLADALPGATT-----
>tr|A0A078MU94|A0A078MU94_9MICC NAD-dependent protein deacetylase OS=Arthrobacter sp. 11W110_air GN=cobB PE=3 SV=1
-----------------------------------RLLSGRRLALLTGAGLSTDSGIPDYRGPGAP--PRNP---MTYQQFIGDQALRRRYWA--RNHVG
WHRAVPNAGHRAVAELE-RRGLITGLITQNVDRLHTDAGSRQVIDLHGRFDQVICLDCGSRFSYLEEITDVADCPVCG--GTLKPDFVYFGENPKRVAAA
FDILAAADALVVAGSSLTVMSGLRFVRRAHKDGKPVVIINRGPTRGDELADLKLDIGTAPALTYLARHLPDLAA-----
>tr|H5X8F3|H5X8F3_9PSEU NAD-dependent protein deacetylase OS=Saccharomonospora marina XMU15 GN=cobB PE=3 SV=1
-----------------------------------RVLGERGVVVVSGAGISTESGIPDYRGAGGTLRRHSP---MTYQEFVGSEEGRRRYWA--RSHLG
WARARPNAGHHAVAALR-AGGYLSGIITQNVDGLHQRAGASAVAELHGSLARVVCLSCRRTSAFRADLAELVPCAACGS-GVLKPDVVFFGENPRLVRRC
YELVEEASAVLVLGSSLTVLSGLRFVRRAAEQGKPVLIVNQGETRGDSHARLRVELPLGKALTEVAGRLGCA-------
>tr|K0JZH5|K0JZH5_SACES NAD-dependent protein deacetylase OS=Saccharothrix espanaensis (strain ATCC 51144 / DSM 44229 / JCM 9112 / NBRC 15066 / NRRL 15
-----------------------------------RAVAARDVVVLSGAGLSTESGIPDYRGAAGSLRRHTP---MTYDEFTGSEAGRRRYWA--RSHLG
WRRADPNTGHHAVAALR-LAGFVSGVITQNVDGLHHAAGTSDAVELHGNLDRVVCLDCRRLTPFTADLADVVGCADCA--GVLKPDVVFFGENPRRVEEC
GRLVDEARSVLVLGSSLTVMSGLRFVRRAAGAGTPVLIVNQGETRGDRHASARVDLPLGRALTELCNILRVDLQ-----
>tr|H0K1C7|H0K1C7_9PSEU NAD-dependent protein deacetylase OS=Saccharomonospora azurea SZMC 14600 GN=cobB PE=3 SV=1
-----------------------------------RVVGDGGVVVLSGAGLSTESGIPDYRGADGTLTRHLP---MTHQEFLSSDEGRRRYWA--RSHLG
WARARPNAGHRAVAALQ-RSGHVAGVITQNVDGLHQAAGAEGVVELHGSLARVVCLDCGRTGSFRADLPELVPCSACGT-GRLKPDVVFFGDSPRRVDEC
RRLVDDARAVLVLGSSLAVMSGLRFVRQAAKAGIPVLIVNRGETRGDAHARVRVDRPLGSALTELVARLGG--------
>tr|H5XHA4|H5XHA4_9PSEU NAD-dependent protein deacetylase OS=Saccharomonospora cyanea NA-134 GN=cobB PE=3 SV=1
-----------------------------------RVVGEGGVVVLSGAGLSTESGIPDYRGADGTLRRHVP---MTHQEFVGSEAGRRRYWA--RSHLG
WARARPNAGHDAVAALQ-HGGLLSGMITQNVDGLHQAAGARGVVELHGNLGRVVCLDCGHATSFRADLPEVVSCSACGD-GVLKPDVVFFGDNPRRVEEC
RRLVDDASAVLVLGSSLAVMSGLRFVRHAARAGKPVLIINQGETRGDVHALVRVDRPLGSALTELADRLGQRVA-----
>tr|I1D0L0|I1D0L0_9PSEU NAD-dependent protein deacetylase OS=Saccharomonospora glauca K62 GN=cobB PE=3 SV=1
-----------------------------------RVVGEGGVVVLSGAGLSTESGIPDYRGVDGTLRRHLP---MTHQEFVGSEENRRRYWA--RSHLG
WARARPNAGHEAVAALQ-HGGYLTGVITQNVDGLHQAAGAEDVIELHGNLGRVVCLDCGRVSSFRAEVPEVVSCSACGT-GVLKPDVVFFGDSPRRVEEC
RRLIDAANAVLVLGSSLAVMSGLRFVRQAAGAGKPVLIINKGETRGDAHALVRVDRALGSALTELTERLGCRWP-----
>tr|I0UY03|I0UY03_9PSEU NAD-dependent protein deacetylase OS=Saccharomonospora xinjiangensis XJ-54 GN=cobB PE=3 SV=1
-----------------------------------RVVGEGGVVVLSGAGLSTESGIPDYRGEGGTLRRQAP---MTHQEFVNSEDGRRRYWA--RSHLG
WDRARPNDGHRAVAALR-RRGHLLGVITQNVDGLHQAAGADGVVELHGSLGRVVCLDCGHNSSFSAELPEVVSCAACGT-GVLKPDVVFFGDSPRRVERC
RRLIDDAAAVLVLGSSLAVMSGLRFVRQAASAGKPVLIVNRGETRGDAHAVLRVDRPLGAALIELAERLGCPVA-----
>tr|C7MQF7|C7MQF7_SACVD NAD-dependent protein deacetylase OS=Saccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101) G
-----------------------------------RVVGGRGVVVLSGAGLSTESGIPDYRGAGGTLRRHSP---MTYQEFVGSEAARQRYWA--RSHVG
WPQARPNVGHRAVAALQ-RDGYVFGVITQNVDGLHQAAGATAVIELHGSLSRVVCLECGQLSSFRADLPETVPCHACGT-GVLKPDVVFFGENPRRVEEC
YRLVDDAKALLVLGSSLAVMSGLRFVRHAAKAGKPVLIVNKGETRGDPHALVRVDRTLGPALAELADRLGCPLS-----
>tr|U2G7X1|U2G7X1_9CORY NAD-dependent protein deacetylase OS=Corynebacterium pseudodiphtheriticum 090104 GN=N579_05680 PE=4 SV=1
-----------------------------------DQLHLGPAMVLTGAGVSTDSGIPDYRGPKGKMT-HRP---MTYQEFCHDPAASHRYWA--RSFIG
WRRAVPNRTHYALVELE-RAGFVRGVLTQNVDGLHAEAGQHNVVALHGNLDTVSCLDCGLREHYLEDLPQMVGCLRCDS-ARLKPDVVYFGEAPERKQQA
RAMAAESASLIVAGSSLAVMSGYRFVLDMLASGRPVAVINGGPGRADARVDVLWRTQVGPAFDDLLDALGL--------
>tr|E3J6G8|E3J6G8_FRASU NAD-dependent protein deacetylase OS=Frankia sp. (strain EuI1c) GN=cobB PE=3 SV=1
-----------------------------------AAAAGGRVAVLTGAGISTESGIPDYRGPSGAPRNHTP---MTYQQFTGDPEFRRRYWA--RSHAG
WRAAPPNAGHRAVAALE-RAGLLAGIVTQNVDGLHQAGGARDVIELHGNLARVLCSDCGDVSAFRAVLAEIVGCRRCG--GRLEPDVVFFGATPRRVDAA
MDVVAGSRLLLVLGSSLTVMSGYRFVLRAGQLGVPVAIVNQGPTRADARAGLIVDAPLGEILPALAAHLAPQA------
>tr|H5UNG9|H5UNG9_9MICO NAD-dependent protein deacetylase OS=Mobilicoccus pelagius NBRC 104925 GN=cobB PE=3 SV=1
-----------------------------------DLVAGGRVCVLTGAGMSTESGIPDYRGPDGQ-RRVQP---MTYQEFTAGPDSRRRYWS--RAHVG
WQASRPNAGHRVVAALQ-RHGFADSIITQNVDGLHQRAGAADVLELHGTLSLVRCLTCENRIPFAETLADLATCERCGA-DTLKPDVVYFGENPKRVARA
YEAVDASQTLLVLGSSLKVMSGYRFVRHSHKAGRPVAIVTRGRTRGDAEATHRLDAGLGETLVALARTLGLEED-----
>tr|A0A0K1FB04|A0A0K1FB04_9MICO NAD-dependent protein deacetylase OS=Arsenicicoccus sp. oral taxon 190 GN=cobB PE=3 SV=1
-----------------------------------RLVHSGGVVALTGAGMSTESGIPDYRGPDGQ-RRVQP---MTYAEFTGTSAARQRYWA--RAFVG
WEAARPNAGHRALAALQ-RTGLITDVITQNVDGLHQEAGSTRVLELHGTLAVVRCLTCEDRTSFQ-ALPDLARCVVCGA-DTLKPDVVFFGEPPRRVDES
YRRVEAAEALLVLGSSLKVMSGYRFVRRAHALGIPVAIITRGRTRGDDEASWQLDAPLGPALTGIATRLGIEED-----
>tr|A0A0M8KQM3|A0A0M8KQM3_9MICO NAD-dependent protein deacetylase of SIR2 family OS=Brachybacterium sp. SW0106-09 GN=Y09_1868 PE=4 SV=1
-----------------------------------ALLRDRPVAVLSGAGMSTGSGLPDYRGRDAV--PRSP---MTYQEFMGHDLARRRYWA--RSTVG
WESALPGRSHRLLAVLSPAAFPVTAVITQNVDGLHAAAGSDPVIDLHGRLDRVRCQQCDALSSLAAEVDRYPPCPLCG--GILKPDVVFFGESRRVVASA
FTALEEASALLVLGSSLTVQSGLRFVRAARKQGKPVVILNDGPTRADPDASLRVHGRLEDVLAQWADAVGAELG-----
>tr|I6XPL5|I6XPL5_PROPF Transcriptional regulator, Sir2 family OS=Propionibacterium propionicum (strain F0230a) GN=HMPREF9154_3042 PE=4 SV=1
-----------------------------------NLFRGRPTVVLTGAGMSTGSGLPDYRGRDAV--PRSP---MTFQEFTGSDLSRRRYWV--RSTVG
WNAARPGLAHLALAGLG-RHTPLTGVVTQNVDGLHQAAGSEPVVDLHGNLARVVCLGCGRLSGVAAEVEGYPACPVCG--GMLKPDVVYFGENRRVVEAA
NALFDAAEVLLVLGSTLTVMSGLRFARQAVKQGKDVIIAGDGVTRADDLATLRIHGRLEHILPFWADALRAG-------
>tr|Z9JVS5|Z9JVS5_9MICO NAD-dependent deacetylase OS=Brachybacterium phenoliresistens GN=BF93_10525 PE=4 SV=1
-----------------------------------EILSGARTCVLSGAGMSTASGLPDYRGRDAV--PRSP---MTYQEFTGSDLARRRYWA--RSTVG
WTAARPNPGHDALARLG-PLLPVHGIITQNVDDLHRRAGSSPVVDLHGRLDAVRCLGCDALTSVAAEVDRYPPCGLCG--GVLKPDVVFFGESRPTVRRA
MAILEESGALLVLGSSLTAWSGLRFVRAAERAGTPVVILNDGPTRGDVHARLRLHGRIESVLARWESRLAPAG------
>tr|C7MA66|C7MA66_BRAFD NAD-dependent protein deacetylase, SIR2 family OS=Brachybacterium faecium (strain ATCC 43885 / DSM 4810 / NCIB 9860) GN=Bfae_29
-----------------------------------A-LPDRPVAVLTGAGMSTGSGLPDYRGRDAVP--RSP---MTYQEFMGHDLARRRYWA--RSTVG
WETARPGRAHRLLAALG-DTLFSTAVITQNVDGLHQAAGSDPVIDLHGRLDRVRCQHCDALSSLAAEVDRYPPCPLCG--GILKPDVVFFGESRRVVTAA
FTALEAAQALLVLGSSLTVQSGLRFVRAAVRTGTPIVIVNDGPTRADSLATLRVHGRIEDILAVWAGAA--EER-----
>tr|A0A022L0B3|A0A022L0B3_9MICO NAD-dependent deacetylase OS=Brachybacterium muris UCD-AY4 GN=D641_0107670 PE=4 SV=1
-----------------------------------DLLRGEPTAVLTGAGMSTSSGLPDYRGRDAV--PRAP---MTFQEFMGSDLARRRYWA--RSTVG
WTRARPNCGHELLARLQAGDLPVTGVITQNVDALHQQAGSRPVVDLHGRLDRVRCMGCDTVSGLASEVDRYPACPLCG--GILKPDVVFFGESRRVVREA
YALVEEASRLLVLGSSLTVQSGLRFVRAAVKAGTPVVIVNDGPTRGDEQATLRIHGRIEDVLAAWAGS-----------
>tr|G0PUJ9|G0PUJ9_STRGR NAD-dependent protein deacetylase OS=Streptomyces griseus XylebKG-1 GN=cobB PE=3 SV=1
-----------------------------------EALRGGGVLVLSGAGISTESGIPDYRGEGGSLSRHTP---MTYQDFTADAGARRRYWA--RSHLG
WRRARPNAGHRAVAAFG-RRGLLSGVITQNVDGLHQAAGSADVVDLHGRLDRVVCLSCGAFGPFAPDLTDVVPCAVCG--GVLKPDVVFFGESPPRVEHC
RALVDAASALLVLGSSLTVMSGLRFVRQAERSGLPVLIVNRDPTRGDRHALPRIALPLGDALTTAAGRLGVRVD-----
>tr|A0A0M8T0V1|A0A0M8T0V1_9ACTN NAD-dependent protein deacetylase OS=Streptomyces sp. MMG1522 GN=cobB PE=3 SV=1
-----------------------------------EALRGGGVLVLSGAGISTESGIPDYRGEGGSLSRHTP---MTYQDFTADAAARRRYWA--RSHLG
WRRARPNAGHRAVAAFE-RRGLLSGVITQNVDGLHQAADSEGAVDLHGRLDRVICLSCGDLSAFAPDLTDVVPCVVCG--GVLKPDVVFFGEAPPRVERC
RALVRGADALLVLGSSLTVMSGLRFVRQAADAGTPVLIVNRDATRGDRHAVTRVALPLGPALTAAAGRLGVPLP-----
>tr|D6ALG3|D6ALG3_STRFL NAD-dependent protein deacetylase OS=Streptomyces roseosporus NRRL 15998 GN=cobB PE=3 SV=1
-----------------------------------EALRGGGVLILSGAGLSTESGIPDYRGEGGSLSRHTP---MTYQDFTADAGARRRYWA--RSHLG
WRRARPNAGHRAVAAFG-RQGLLSGVITQNVDGLHQAAGSDDVVDLHGRLDRVVCLSCGTFSPFAPDLTDVVPCTSCG--GVLKPDVVFFGEAPPRVEHC
RTLVREARTLLVLGSSLTVMSGLRFVRQAAGAGTPVLIVNRDATRGDRHAVTRIALPLGSALTGAAGRLGVHVP-----
>tr|S2YHS8|S2YHS8_9ACTN NAD-dependent protein deacetylase OS=Streptomyces sp. HGB0020 GN=cobB PE=3 SV=1
-----------------------------------DALSVGGVLVLSGAGISTESGIPDYRGEGGSLSRHTP---MTYQDFTASAEARRRYWA--RSHLG
WRRARPNAGHRAVSAFE-RHGLVSGVITQNVDGLHQAAGSEDVVELHGSLDRVGCLSCGDFLPFEPDLTDVVPCTICG--GVLKPDVVFFGETPPRVEHC
RRLVDEATSLLVLGSSLTVMSGLRFVRQAAQSGKPVLIINRDATRGDRHALTRVGLPLGTALTTVAGQLGIPVD-----
>tr|F5HJ98|F5HJ98_ANOGA AGAP013148-PA OS=Anopheles gambiae GN=AgaP_AGAP013148 PE=3 SV=1
-----------------------------------KFLDKPHILVLTGAGISTESGIPDYRSEGVGLANHKP---IQHGDFVKSEATRKRYWA--RNYVG
WPSIAPNVTHYTLARLER-EGRISGIVTQNVDRLHGKAGSKQVIELHGSGFDVICIGCN-RIDMEDELSMIPPCPQCGG--NLKPEIVFFGDNPMRIEKV
VRMIIESDGVLVLGSSLTVFSGYRIILQAKELGLPVAIVNIGATRGDPKADLKISARCGEVMANLFKPAR---------
>tr|A0A0K8TT56|A0A0K8TT56_TABBR Putative sirtuin 4 (Fragment) OS=Tabanus bromius PE=2 SV=1
-----------------------------------KYLSKPNTLVLTGAGISTESGIPDYRSEGVGLATNKP---IQHIEFVKSEAIRRRYWA--RNYVG
WPEFQPNATHHALARFER-EGRILGIVTQNVDKLHTKAGSSNVIEIHGSGYTVMCLSCD-KMPMPDEIPQVPPCPNCGG--NLKPEIVFFGDNPKRILRI
TKLICESDGLLVLGSSLLVFSGYRLVLQTKDLNLPVAIVNIGPTRGDNLADIKISAKCGDIIPKLFDFQKK--T-----
>tr|Q17DV2|Q17DV2_AEDAE AAEL004004-PA OS=Aedes aegypti GN=AAEL004004 PE=3 SV=1
-----------------------------------KFLDKPHILVLTGAGISTESGIPDYRSEGVGLANHKP---IQHGDFIKFESVRKRYWA--RNYVG
WPAIAPNVTHYTLAKLER-EQRISGIVTQNVDKLHTKASSKSVVELHGSGYNVICVGCD-HIPMEDELPQIPPCPECGG--ALKPEIVFFGDNPMRIERV
VRMIIESDGVLVLGSSLTVFSGYRIVLQAKELGLPVAIVNIGDTRGDPKADLKISARCGELMQNLFKK-----------
>tr|T1PB20|T1PB20_MUSDO Sir2 family OS=Musca domestica PE=2 SV=1
--------------------------------------DKPKIVVLTGAGISTESGIPDYRSEGVGLANHKP---IQHMEFVRSPSVRQRYWA--RNFVG
WPSTEPNATHYSLARFER-EGRLQCVVTQNVDRLHTKAGSENVIELHGSGYVVKCLSCD-KIDFKDEIPQIPNCPQCDDN-RLKPEIVFFGDNPKRVNSI
AEMIYAGDGLLVLGSSLLVFSGYRMVLQAKDLNLPVAIVNIGETRADHLADLKLSAKCGDVIPKLFNFKNK--------
>tr|A0A0C7BJ48|A0A0C7BJ48_9FUNG Uncharacterized protein OS=Rhizopus microsporus GN=RMATCC62417_06636 PE=4 SV=1
-------------------------------------MIATRGSNLRTIGLSTDSGIPDYRGDQGTYRRHRP---ILYHELLSSHLYRQRYWS--RSYLG
WPQALPNGSHHALALLMTQSPYIQNIITQNVDYLHTKAPAERLLELHGTLYKVECMDCD-EYDWNAELPDIPPCTSCGS-QKMKPKVVFFGENKPITKRA
EQLVNDCSAVVIIGSSLATYSSYRLIRMAHQQNKPIGILTKGPTRADSLMAWKGEVGCTPVLVELSRRLKGTM------
>tr|A0A0C9LVE1|A0A0C9LVE1_9FUNG DHS-like NAD/FAD-binding domain-containing protein OS=Mucor ambiguus GN=MAM1_0130c06102 PE=4 SV=1
--------------------------------------MLSLVSQLI---------RAYQTIEVISYRNHRP---ILYHELASSHNYRQRYWS--RSYLG
WPESQPNATHDILKKLV-DHGYIQNIITQNVDSLHTKAPNQNLLELHGTLYKVECMDCGDSADWKAELPQIPPCLHCGS-QKMKPKVVFFGENKHVTDQA
EKFIRDSSAVLVIGSSLATYSSYRLLRLAHQLHKPIGIVTKGPTRADNLMQWKGEVGCSPVLTMVYKNLIGVN------
>tr|S2JFF1|S2JFF1_MUCC1 Uncharacterized protein OS=Mucor circinelloides f. circinelloides (strain 1006PhL) GN=HMPREF1544_04252 PE=4 SV=1
-------------------------------------MILTFPPAID--------REQTTHVFLISYRNHRP---ILYHELASSHNYRQRYWS--RSYLG
WPESLPNATHDTLKKFV-DHGYIQNIITQNVDNLHTKAPDRNLLELHGTLYKVECMDCGDSADWNDELPKIPPCLHCGS-QKMKPKVVFFGENKHVTDQA
EKFIQDSSAVLVIGSSLATYSSYRLLRLANQLNKPIGIVTKGPTRADNLMQWKGEVGCSPVLTMVYSNLIGLN------
>tr|A8X439|A8X439_CAEBR Protein CBG07777 OS=Caenorhabditis briggsae GN=CBG07777 PE=4 SV=1
-----------------------------------SLVSVEKLLIVTGAGISTESGIPDYRSKNVGLATQKP---LYYHEFMKSIECRQSYWL--RHFLS
WPQAAPNINHHTLANWES-SEQFLWLVTQNIDGLHVKAGSDKVTELHGNWRYVKCTTCG-TETFQHEMPSVPTCPCCGG--IMKTDVTFFGETSTKLNFA
FEKANECGGILTLGSSLAVLPGSRLVHQAHSQNKPIFIVNIGPTCVDHLATMKLENKISDVLKEI--------------
>tr|A0A091GR43|A0A091GR43_BUCRH NAD-dependent protein deacetylase sirtuin-4 (Fragment) OS=Buceros rhinoceros silvestris GN=N320_06241 PE=3 SV=1
-----------------------------------HFVNSKRLFVMTGAGISTESGIPDYRSEGVGLADRRP---IKHAEFVRSASVRQRYWA--RNFMG
WPSYQPNTAHMVLRDWE-NLGKLHWLVTQNVDALHTKAGSQRLTELHGCMHRVFCLDCGDQILWKAFLTDVPACRKCGG--ILKPNVTFFGDSSRKVDFV
YQRLAESDSMLVAGSSMQVYSGYKFALAAQEKRLPVAVLNIGPTRLDHFATLKLNSRCGELLPLI--------------
>tr|A0A0L0H4V4|A0A0L0H4V4_SPIPN Uncharacterized protein (Fragment) OS=Spizellomyces punctatus DAOM BR117 GN=SPPG_08128 PE=4 SV=1
-----------------------------------EFLGEGKCAVLTGAGVSTDSGVPDYRGPSGVYRDYKP---IRYQEFVSSHSIRQRYWA--RSYLG
YPQARPNRTHFAIHELE-KRSWVNGIVTQNVDGLHLG---NNVLELHGSLHKVHCLSCHHTIPLAEEIT-YPACDACGV-GMYKPSVVFFGENPSVRDES
FSLIDTSNSVLAVGTSLQVYSAFRLIQRAKAQGKRVAVLSLGPTRADGVVDVKVDDGSSDVLEDVVEGLA---------
>tr|H9JTH2|H9JTH2_BOMMO Uncharacterized protein OS=Bombyx mori GN=LOC101742457 PE=3 SV=1
-----------------------------------EFLNHNKILILTGAGISTESGIPDYRSEDVGLANHKP---IQYQEFVKYPKVRQRYWA--RNYIG
WPCVQPNVTHLCIRELEK-KGKVTSIVTQNVDRLHHKAGSEKVIELHGTSYLVQCLKCP-EIDMESELSRAPLCPKCEG--PLKPDIVFFGDNPKRVEQV
RKEVTSSDAVFVMGSSLTVYSSYRIILQARDEHKNIAILNIGPTRADDIVNIKVSTKCGDVLPELCKSLN---------
>tr|A0A0L7L9D9|A0A0L7L9D9_9NEOP NAD-dependent protein deacetylase OS=Operophtera brumata GN=OBRU01_12882 PE=4 SV=1
-----------------------------------EFLKHDKILFLTGAGISTESGIPDYRSEEVGLANHKP---VQYQEFVKYPKVRQRYWA--RNFIG
WPNIEPNITHL---------SKVTSIVTQNVDRLHHKAGSCNVIELHGTGYIVKCLSCT-EVDIEKDLSKVPLCPKCEG--PLKPDIIFFGDNPRKVELV
RNQVTSSDAVFVLGSSLTVYSSYRIILQAKEEGKDIAILNIGPTRADNLVHLKVETKCGDILPELCNSLS---------
>tr|G6CI01|G6CI01_DANPL Uncharacterized protein OS=Danaus plexippus GN=KGM_15446 PE=3 SV=1
-----------------------------------EFLKNKQLLVLTGAGISTESGIPDYRSEEVGLANHKP---IQYQEFVKYPRVRQRYWA--RNFVG
WPAIKPNATHHVIRDLEK-IGKVSSVVTQNVDRLHHKAGSMNVIELHGSGYIVKCLNCP-EIDMKSELSKTPLCPECEG--PLKPDIVFFGDNPKRVEQV
RNEVSCSDAVFVLGSSLTVYSSYRIILQAKEEGKEVAILNIGPTRADDMADLKVSTKCGDILVDICKTIM---------
>tr|A0A099YWM9|A0A099YWM9_TINGU NAD-dependent protein deacetylase sirtuin-4 (Fragment) OS=Tinamus guttatus GN=N309_13422 PE=3 SV=1
-----------------------------------HFIRSKKLFVMTGAGISTESGIPDYRSEGVGLADRRP---VQHGEFVSSARARQRYWA--RNFVG
WPSRWPNAAHLVLRDWE-QRGKLHWLVTQNVDALHGKAGSQRLTELQRCTHRVSCLGCGDQTSWKAFLTDVPACSKCGG--ILKPDVTFFGDTSRKVNFV
HQRLAESDSMLVAGSSMQVFSGYRFALAAREKRLPIAVLNIGPTRLDHFASLKLNSRCGELLPLI--------------
>tr|R7VC11|R7VC11_CAPTE Uncharacterized protein OS=Capitella teleta GN=CAPTEDRAFT_172150 PE=3 SV=1
-----------------------------------DFVGARKLVVLTGAGLSTESGIPDYRSDKVGLANRRP---VDHSEFMRNASSRQRYWA--RNFVG
WPSHLPNASHEALYAWEK-AEKLQWLITQNVDSLHHKAGSSRVSELHGCTHRVKCMDCH-LYRWDFLLTDVLDCQKCGG--ILKPDVVFFGDNIKKVEFI
YDQIRAGDGLLVIGSSLFVYSGYRFALRAVELGKPLAILNIGETRADHLVNLKVSALCGEILPQIRIS-----------
>tr|A0A0R3PFK1|A0A0R3PFK1_ANGCS Uncharacterized protein OS=Angiostrongylus costaricensis PE=4 SV=1
-----------------------------------NKVAIDRLLVLTGAGVSTESGLPDYRSEKIGLENYRP---VTIQEFMASESARKRFWS--RNFLA
WPRAKCNKAHFTVASWER-SDKFVWLITQNVDGLHMKAGSTLLTELHGCGHRVRCMQCN-VTSW-MEVDELPSCKKCGG--ILKTDVVFFGDNAQEVHLC
YEKLDECSGVLVLGSSLTVNSGFRFVYYANLQGKPVLIVNIGPTRADDFADMRISVPVTEIITML--------------
>tr|A0A0D8Y541|A0A0D8Y541_DICVI Transcriptional regulator, Sir2 family OS=Dictyocaulus viviparus GN=DICVIV_01799 PE=4 SV=1
-----------------------------------DKVAIDRLLVLTGA------GIPDYRSEKTGLANHRP---ITIQEFMACESARKRYWC--RNFLA
WPRAICNKAHLAIASWER-SEKFVWLITQNIDALHTKAGSTLLSELHGCGHRVKCMECG-VTGW-SEIEELPSCSKCGG--ILKTDVVFFGDNAQMVDLC
YEKIDECSGVLVLGSSLTVNSGFRFPYCASLQGKPVLIVNIGPTRADNFAEMRISAPVTEIITKLSLL-----------
>tr|A0A0F5CPQ8|A0A0F5CPQ8_PRIPA Sir-2.2 OS=Pristionchus pacificus GN=PRIPAC_4646 PE=3 SV=1
-----------------------------------RELSVDRLFVMTGAGISTESGIPDYRSAGVGQANHRP---VTHQEFMGSQHTRQRFWA--RNFLA
WPDAQPNETHRTIAKWER-SDRFHWLVTQNVDGLHTKAGSNRLTELHGCGHRVKCMECD-TMSW-TTIEELADCPSCDG--VLKTDVVFFGDNPRDVDLC
YEKVEESDGVLVLGSSLSVMSGYRFVHHASLRNLPIFIVNIGPTRADHLATHRIHCIASMIVPRI--------------
>tr|E5SI73|E5SI73_TRISP NAD-dependent deacetylase OS=Trichinella spiralis GN=Tsp_04138 PE=4 SV=1
-----------------------------------KYLSMRFLFVITGAGISTESGIPDYRSEGVGRAHLKP---IQYVDFLNSARVRRRYWA--RNYVA
WRSVKPNRTHAILNDWEK-NGWIHWMVTQNVDNLHCKAGSHRVTELHGNGFRVRCISCE-RWNWEADLDNMPVCDNCRG--ILKPDIVFFGENPITVHFV
EDRLSESDGLLAVGTSLQVLSVFRLVHIAYEIKMPILIVNIGPTRADDLATIKISSNCSQVLATAYE------------
>sp|A9A0B2|NPD_DESOH NAD-dependent protein deacylase OS=Desulfococcus oleovorans (strain DSM 6200 / Hxd3) GN=cobB PE=3 SV=1
-----------------------------------KVLGASRAAVFSGAGVSAESGIPTFRDPGGVWR-LNP---AEVGSLEKNPE---KLVA--MFMEL
LADAIPNPGHRALFDLE-RMGILQAVITQNIDNLHQEAGNTQVIEMHGNGFRFRCLKCRSRRS-HAASI-MPDCDLCG--SGMRPDVVMFGETME-VENA
FAAARSCDVMLALGTSGVVTPAAQIPAEAKASGAKVIVINPNENGFARVCDIYISMKTGQALPRIVEQVKKIRS-----
>tr|A0A077YVL7|A0A077YVL7_TRITR NAD dependent ADP ribosyltransferase sirtuin 4 OS=Trichuris trichiura GN=TTRE_0000007501 PE=3 SV=1
-----------------------------------DELKSKRLVVMTGAGISTESGIPDYRSEKVGRANHKP---VEFQEFMNEEPVRRRYWA--RSYVA
WPSVQPNATHKKLAEWEQ-RSRIHWLITQNIDCLHRKAGSRRLTELHGNAYSVRCMKCS-RWDWNADLPATPNCPKCGG--ITKPEIVFFGEMPVEMNDC
YIRVDEADAMLVLGSSLQVLSGFRFVYQMYEQGKPVLIVNIGGTRADDMATVKVSSKCTTVMELVDDVQALN-------
>tr|W5K406|W5K406_ASTMX Uncharacterized protein OS=Astyanax mexicanus PE=3 SV=1
-----------------------------------TFVQASRLFVMTGAGLSTESGIPDYRSEGVGLADRRP---LQHSEFVHSAKARQRYWA--RNYVG
WPSHLPNSAHYALRDWE-RKGKVHWLVTQNVDALHSKAGHQGLTELHGCSHRVVCLGCGQLTAWEALLEDVPACQACGG--ILKPQVTFFGDTARTVEFV
HNKLAECDALLVAGSSLQVYSGYRFLLAAKERQIPVAILNIGPTRADHLAQLKVSARCGEVLSSLNAS-----------
>tr|A0A0P4W6X6|A0A0P4W6X6_9EUCA Uncharacterized protein OS=Scylla olivacea PE=4 SV=1
-----------------------------------EFLTTKRLFVLTGAGISTESGIPDYRSEGVGLADRRP---IQYKQFVDSSKARQRYWA--RNYMG
WPSVIPNTAHTCLTAWER-SGKLACVVTQNVDRLHHKARTSNVLELHGSAFNVVCMNCR-QVLLTLELTQVPPCEGCGG--IMKPDLVFFGESPQRVERV
KRELAKCDALLVLGSSLYVYSGYRFILAGVERGMRMCGVNIGPTRGDPHFLFRINARCGDVLPRLHV------------
>tr|A0A0P7WY88|A0A0P7WY88_9TELE NAD-dependent ADP-ribosyltransferase sirtuin-4-like OS=Scleropages formosus GN=Z043_112080 PE=4 SV=1
-----------------------------------NFVRSRRLFAITGAGLSTESGIPDYRSEGVGLSDRRP---MQHSEFLSNAKARQRYWA--RNYVG
WPSHQPNAAHVALRSWE-TAGKLHWLVTQNVDALHSKAGSQQLTELHGCTHRVVCLGCGSVSPWAAFLTDVPSCEVCGG--ILKPQVTFFGDTDRTVRFV
HQKLAESDGVLVAGSSLQVFSGYRFLLAASERKVPVAILNIGPTRADHLASVRVSARCGEILPAILTL-----------
>tr|A0A085MJ94|A0A085MJ94_9BILA Uncharacterized protein (Fragment) OS=Trichuris suis GN=M513_01801 PE=4 SV=1
-----------------------------------DELKSKRLVVMTGAGISTESGIPDYRSEKVGRANHKP---VEFQEFMNEESVRRKYWA--RSYVA
WPSVLPNVTHKKLAEWEQ-RSRIHWLITQNIDCLHRKAGSRRLTELHGNAYNVRCMNCN-RWDWNADLPSTPSCNKCGG--IVKPEIIFFGELPIEMNDC
YVRVEEADAMLVLGSSLEVLSGFRFVYQMYEAGKPILIVNIGNTRADEMATVKVSSKCTTVMELIDDDMKALH------
>tr|F1QHM6|F1QHM6_DANRE Uncharacterized protein OS=Danio rerio GN=sirt4 PE=3 SV=1
-----------------------------------AFIQASRLFVISGAGLSTESGIPDYRSEGVGLANRRP---MQHSEFVRSEKSRQRYWA--RNYVG
WPSHQPNSAHLALRDWE-EKGKLHWLVTQNVDALHLKAGQQRLTELHGSTHRVVCLDCGELTLWEAFLEEVPACNACGG--VLKPEVTFFGDVKRTVHFV
HNKLAESDAVLVAGSSLQVFSGYRFLLAASERKLPIAIVNIGATRADHLTDIRVSARCGEVLPAIKLS-----------
>tr|K3WZS6|K3WZS6_PYTUL Uncharacterized protein OS=Pythium ultimum DAOM BR144 GN=PYU1_G010453 PE=4 SV=1
-----------------------------------SFLGRGRTVLLTGAGISTDSGIPDYRGANGVYRDFKP---LQYQEFVKAHTYRQRYWA--RSFLG
WPHAQPNASHDAVTQLQ-QHAVVSDILTQNVDRLHSKSGAKGVLELHGCLHEVECTNCRSVVKVAQDIT-YPPCLQCG--GIMKPKVVFFGENPVVKNQS
FEHVDKADALLVVGSSLQVFSAMRLLNRARERKIPIAIVNLGPTRGDDACDLRLDTHCTDVLATVAHDFSL--------
>tr|W2Q8M8|W2Q8M8_PHYPN Uncharacterized protein OS=Phytophthora parasitica (strain INRA-310) GN=PPTG_10983 PE=4 SV=1
-----------------------------------KFLGRGKTMVLTGAGISTDSGIPDYRGPNGVYRDFRP---IQFQEFIGAHTYRQRYWA--RSFLG
WPNTQPNGSHYALTELQ-QAAAISSILTQNVDRLHTKSGSHSVVEMHGSLHEVECQGCGQVTSVAKDIS-YPACSNCS--GIMKPRVVFFGENPATRMTA
LERVSDANALLVIGSSLKVFSAMRLINHAHARKIPIAIVNLGPTRADELCSLRIDKPCTSLLSEVAGLY----------
>tr|K7FZE4|K7FZE4_PELSI Uncharacterized protein OS=Pelodiscus sinensis GN=SIRT4 PE=3 SV=1
-----------------------------------RFVHSQRLLVMTGAGISTESGIPDYRSEGVGLADRRP---IQHAEFVRSASARQRYWA--RNFVG
WTSHQPNAAHLALRNWE-KLGKLHWLVTQNVDALHTKAGSQRMTELHGCTHRVLCLGCGEQTPWRAFLTDVPACSRCGG--ILKPDVTFFGDTSRKVDFV
HRRLAEADSMLVAGSSLQVYSGYRFALAAHEKKLPIVIINIGPTRSDHFASMKVNSRCGELLPLIVPR-----------
>tr|B3S4A5|B3S4A5_TRIAD Putative uncharacterized protein OS=Trichoplax adhaerens GN=TRIADDRAFT_59014 PE=4 SV=1
-----------------------------------DFMKSKKLLILTGAGVSTASGIPDYRSKGVGLANQRP---MQYSDFLENDENRKRYWS--RNFTG
WSSVKPNLTHNFIAKLEQ-LKLLHWVVTQNVDGLHQRAGSSRLTELHGTMHEVICLQCQ-IILWTVFIAELAKCE-CGG--VLKPNVVFFGGSSKINEEV
RQHVDEADSILVVGSSLQTYSAYRIISRASDMRKPIGIVSIGETRADHLASFKISINCNQLFENLQLSAYS--------
>tr|E4XH74|E4XH74_OIKDI Uncharacterized protein OS=Oikopleura dioica GN=GSOID_T00010844001 PE=4 SV=1
-----------------------------------MFLRNESLFCLTGAGISTESGIPDYRSKGVGLDNHKP---ITHQEFTRSAHKRQRYWA--RNYVG
YKIREPNENHFAIDKLIK-RGKIRNLVTQNVDGLHLKAGSHDLVELHGNNHRVVCLDCR-IIAWETILTPVCDCPYCGG--ILKPDVTFFGDNNYLVQSC
YESVRNNDACLVVGSSLFVWSGFRFIREAISNGKDVFVINIGETRADAFAKKNNLSSTRKCEVQASLLLNNFVN-----
>tr|A0A024G735|A0A024G735_9STRA Uncharacterized protein OS=Albugo candida GN=BN9_033470 PE=4 SV=1
-----------------------------------YFLGNSNTVVLTGAGISTDSGIPDYRVPNGVYRDFKP---IQYQQFVQQHEYRQRYWA--RSLLG
WPMTKPNLAHKSLTYLQ-KQGIVSSIITQNVDRLHTKSGSTNVCELHGALHEVECIACHHNIQMEIEFT-YPSCPQCG--NIMKPHVIFFGENTKVRQRS
AEIVDDAQALLVIGSSLQVYSALRLVNQAHLKKIHIGIINFGPTRADLLCQERFQNGCTELLDGVQLELVQAN------
>sp|F4P804|SIR4_BATDJ NAD-dependent protein deacylase SIR4 OS=Batrachochytrium dendrobatidis (strain JAM81 / FGSC 10211) GN=BATDEDRAFT_20316 PE=3 SV=
-----------------------------------DFLHHGQTVLLTGAGVSTDSGIPDYRGPQGIYRDFKP---IQYQQFVGPHEFRQRYWA--RSFLG
WPQAQPNASHHAIAALE-SRSHIAGCITQNVDGLHRRAENPNLLEIHGTLHWVNCISCGYKLQVYEEIK-YPHCPECN--GLLKPNVVFFGENPMVRDTS
FKMIDDAKALLVVGSSLQVYSALRLVKRAASTGKPIAILNLGFTRGDELAQIRINLGSSAVLEELASTIR---------
>tr|A0A0P1AZU1|A0A0P1AZU1_9STRA Sir2-family regulator protein OS=Plasmopara halstedii PE=4 SV=1
-----------------------------------KFLGCGKTIVLTGAGISTDSGIPDYRGPNGVYRDFRP---IQFQEFIGAHAYRQRYWA--RSFLG
WPNTQPNGSHYALTELQ-RIGMVPSILTQNVDRLHTKSGSHSVVEMHGSLYEVECQGCGQVTSIARDIS-YPECSNCG--GIMKPSVVFFGENPVTRADA
MERVSDANALLVVGSSLRVLSAMRLINHAHTRKIPIAIVNLGPTRADELCSLRIDKPCMTMLAEVADLY----------
>tr|V8NCL8|V8NCL8_OPHHA NAD-dependent ADP-ribosyltransferase sirtuin-4 (Fragment) OS=Ophiophagus hannah GN=Sirt4 PE=3 SV=1
-----------------------------------GFVRCQRLFVLTGAGISTESGIPDYRSEGVGLADRRP---VQHTEFLRNAAARQKYWA--RNFVG
WPSHQPNAAHRALSSWE-QQGKLHWLVTQNVDALHAKAGSQRMTELHGCTHRVVCLSCEARVSWTAFLPEVPSCSKCGG--VLKPDVTFFGDNCKKVDFV
YQRLEESDAVLVAGSSLQVFSAYKFALAARDRKLPMAIVNIGPTRADALASLKLNSRCGALLPSIVL------------
>tr|A0A067R0A4|A0A067R0A4_ZOONE NAD-dependent ADP-ribosyltransferase sirtuin-4 (Fragment) OS=Zootermopsis nevadensis GN=L798_10230 PE=4 SV=1
-----------------------------------TFISANKLLVLTGAGISTESGIPDYRSEGVGLASRRP---IQYQDFIKKEFVRKRYWA--RNFVG
WPSFLPNSVHFMIKDLEIKHGKVCCVVTQNVDKLHTKAGSRHVIELHGSAFKVMCSDCN-TMDMKGDISQVPSCSQCGG--VLKPDIVFFGDNPQRVEAV
KHEIENCDSLLVLGTSLTVFSSYRILLQVSENKKQIAIVNIGPTRGDKYAHIKVDTKCGDIIPKLLVH-----------
>tr|T1JHL2|T1JHL2_STRMM Uncharacterized protein OS=Strigamia maritima PE=3 SV=1
-----------------------------------DFLSSSRLLVITGAGISTESGIPDYRSEGVGLVQYRP---VQYQEFVKNSSVRRSFWA--RNYVG
WPNVEPNIVHLALSKWEK-AGRLNMLVTQNVEKLHSKAGSELVTELHGSAFRVICLTCH-RVLFTKELHQVPSCLKCGG--ILKPDIVFFGENPMRVNFV
YGKIKEADKILVLGSSLQVYSAYRFMLAARKENKPIAIVNIGATRADDLAEVKVNARCGEVLPKLNLS-----------
>tr|B4H4G5|B4H4G5_DROPE GL18326 OS=Drosophila persimilis GN=Dper\GL18326 PE=3 SV=1
-----------------------------------DFLSKPNVVVLTGAGISTESGIPDYRSEGVGLANHKP---IQHMEFLKSSNVRKRYWA--RNFVG
WPGKQANATHHALSRFER-EMRIQSVVTQNVDRLHTKAGTKNVVELHGSGYVIKCLSCE-RTDFNNEIPLIPDCPQCGG--DLKPDIVFFGDCPRRLDKI
AEMVYNSDGLLVLGSSLLVFSGYRIVLQTKDLKLPVAIVNIGDTRADHLADIKISAKCGDVIPKLFDYRTS--G-----
>tr|B4L644|B4L644_DROMO Uncharacterized protein OS=Drosophila mojavensis GN=Dmoj\GI16299 PE=3 SV=1
-----------------------------------EFLSRPNILVLTGAGISTESGIPDYRSAGVGLANHKP---IQHSEFLKSDAVRKRYWA--RNFVG
WPATQPNATHYALARFER-ELRIQAVVTQNVDRLHSKAGTKNIVELHGSGYVVKCLDCD-RIEFSDEIPAIPTCPQCDG--NLKPEIVFFGDCPRRLDAI
AKMIYTSDGLLVLGSSLLVFSGYRIVLQTKDLKLPVAIVNIGETRADHLADIKISAKCGDVLPKLFDYRPT--T-----
>tr|B4M804|B4M804_DROVI Uncharacterized protein OS=Drosophila virilis GN=Dvir\GJ16687 PE=3 SV=1
-----------------------------------DFLSKPNILVLTGAGISTESGIPDYRSAVVGLANHKP---IQHIEFLKSSSVRKRYWA--RNFVG
WPSTQPNGTHHALARFER-EMRIQSVVTQNVDRLHTKAGSKSVVELHGSGYVVKCLGCE-RIDFKDEIPAIPPCPQCGG--NLKPEIVFFGDCPRRLDAI
AKMVYNSDGLLVLGSSLLVFSGYRIVLQTRDLNLPVAIVNIGETRADHLADIKISAKCGDVIPKLFDYRAT--T-----
>tr|B4JKI2|B4JKI2_DROGR GH12046 OS=Drosophila grimshawi GN=Dgri\GH12046 PE=3 SV=1
-----------------------------------DFLSKPNILVLTGAGISTESGIPDYRSAGVGLANHKP---IQHSEFVKSASVRKRYWA--RNFVG
WPSTQPNSSHHALARFER-EIRLQSVVTQNVDRLHTKAGTKSVIEVHGSGYVVKCLSCD-RCDFKDEIPLIPPCPQCGG--HLKPEIVFFGDSPKRLETI
ARMVYTSDGLLVLGSSLLVFSGYRIVLQTKDLKLPVAIVNIGETRADHLADIKISAKCGDVIPKLFDFSNR--E-----
>tr|A0A034WQI7|A0A034WQI7_BACDO NAD-dependent protein deacetylase sirtuin-4 OS=Bactrocera dorsalis GN=SIRT4 PE=3 SV=1
-----------------------------------DFLSKSNIVVLTGAGISTESGIPDYRSEGVGLANHKP---IQHMEFVRFANVRQRYWA--RNFVG
WPSTEPNHTHHAVARFER-EGRIQSVVTQNVDRLHTKAGSKNVIELHGSGYVVKCLSCE-RIDFRDEIPAIPPCPECSG--HLKPEIVFFGDNPKRVEQI
AKMIYNSDGLLVLGSSLLVFSGYRMVLQTKDLNLPVAIVNIGETRADHLADLKLSAKCGDVLPKLFNFKK---------
>tr|W8ANG2|W8ANG2_CERCA NAD-dependent protein deacetylase sirtuin-4 OS=Ceratitis capitata GN=SIRT4 PE=2 SV=1
-----------------------------------EFLSKPNIVVLTGAGISTESGIPDYRSEGVGLANHKP---IQHMEFLRSADVRQRYWA--RNFVG
WPATVPNHTHYAVARFER-EARIQAVVTQNVDRLHTKAGSKNVVELHGSGYVVKCLTCD-RIDFRDEIPVIPPCPECGG--NVKPEIVFFGDNPRRVDHV
TEMIYNSDGLLVLGSSLLVFSGYRMVLQTKDLNLPLAIVNIGETRADRLADLKLSAKCGDVLPKLFNFKN---------
>tr|B3NV66|B3NV66_DROER Uncharacterized protein OS=Drosophila erecta GN=Dere\GG18482 PE=3 SV=1
-----------------------------------DFLSKPNVLVLTGAGISTESGIPDYRSEGVGLANHKP---VQHMEFVKSAAVRKRYWA--RNFVG
WPATQPNATHHALARFER-EERVQAVVTQNVDRLHTKAGSRNVVEVHGSGYVVKCLSCE-RIDFKDEIPLIPECTQCGG--DLKPEIVFFGDSPRRVDQI
AGMVYNSDGLLVLGSSLLVFSGYRVVLQTKDLKLPVAIVNIGETRADHLADIKISAKCGDVIPKLFDFRTS--K-----
>tr|B4MSG3|B4MSG3_DROWI Uncharacterized protein OS=Drosophila willistoni GN=Dwil\GK19907 PE=3 SV=1
-----------------------------------DFLSKPNILVLSGAGISTESGIPDYRSEGVGLANHKP---IQHLEFVKSSSVRKRYWA--RNFVG
WPSTQPNATHHALARFER-EMRVQAVVTQNVDRLHTKAGSRNIVELHGSGYVVKCLSCE-RIDFKDEIPVIPECPECGG--NLKPEIVFFGDCPRRLDKI
AEMVYNSDGLLVLGSSLLVFSGYRMVLQMKDLKLPVAIVNIGDTRADHLADIKISAKCGDVIPKLFDFRKT--N-----
>tr|A0A0A9WN60|A0A0A9WN60_LYGHE NAD-dependent ADP-ribosyltransferase sirtuin-4 OS=Lygus hesperus GN=SIRT4 PE=4 SV=1
-----------------------------------EFLKSKKLLVVTGAGISTESGLPDYRSEGVGAAKKFP---VQYQTFVKDPDFRKKYWL--RNYLG
WDNLNPNEAHLAITRLER-NNKMIHLVTQNVDSLHLKADTKKVVELHGTSYRVVCLSCS-EVDVAIDIGEVPDCPDCGG--VLKPDIVFFGDNPKRVQFV
NDLVDECDALAVCGSSLTVQSSFRIVTKAHNMQKPIAIVNIGKTRADDLVHFKIDAKCGEVLPAACDLILQENN-----
>tr|H3BG66|H3BG66_LATCH Uncharacterized protein OS=Latimeria chalumnae GN=SIRT4 PE=3 SV=1
-----------------------------------EFIRSKRLIIMTGAGLSTESGIPDYRSEGVGLAERRP---VQHFEFVRSAKARQSYWA--RNYVG
WPSCQPNPAHLALSSWE-KLGKLHWLVTQNVDALHTKAGSRHLTELHGCSHRVVCLDCGHLTPWNEFLTDVPACERCDG--TLKPEVTFFGDTSRKVNFV
HEQLAESDSMLVLGSSLQVYSGYRFVLAAKEKRLPIAILNIGATRADHLAAIKLSGRCGEVLPCILPV-----------
>tr|Q4RXF6|Q4RXF6_TETNG Chromosome 11 SCAF14979, whole genome shotgun sequence OS=Tetraodon nigroviridis GN=GSTENG00027432001 PE=3 SV=1
-----------------------------------GFVTARRLFVVGGAGVSTESGIPDYRSEGVGLADRRP---MQHAEFVRSARARQRYWA--RNFVG
WPSFEPNAAHRALQRWE-DTGKLHWLVTQNVDALHSKAGHKGVTELHGCAHRVVCLDCGAISAWKAFLEDVPPCEACGG--TLKPEVTFFGDTSKTVQFV
QERLAESDAVLVAGSSLQVYSGYRFLLAASERKLPIAILNIGPTRADHLAEVKVSGRCGEVLPLIQPS-----------
>tr|H2UPJ5|H2UPJ5_TAKRU Uncharacterized protein OS=Takifugu rubripes GN=LOC101075845 PE=3 SV=1
-----------------------------------EFVRARRLFVIGGAGVSTESGIPDYRSEGVGLADRRP---MQHAEFVRSAKSRQRYWA--RNFVG
WPSHEPNSSHRALQRWE-EVGNLHWLVTQNVDALHSKAGHKGVTELHGCAHRVVCLGCGVVSAWKAFLEDVPSCEDCGG--ILKPEVTFFGDTNKTVQFV
HQRLAESDAVLVAGSSLQVYSGYRFLLAASDKKLPIAILNIGPTRADHLVELKVSGRCGEVLPLIQPF-----------
>tr|A0A087YJP3|A0A087YJP3_POEFO Uncharacterized protein OS=Poecilia formosa PE=3 SV=2
-----------------------------------DFVRSRRLFVVTGAGLSTESGIPDYRSEGVGLADRRP---MQHTEFTRSAKSRQRYWA--RNFVG
WPSHQPNCAHRALRSWE-EKGKLHWLVTQNVDALHSKAGQTRITELHGCAHRVTCLGCGSITAWSAFLEDVPSCEQCGG--ILKPEVTFFGDTAKTVQFV
QERLAEADAVLVIGSSLQVYSGYRVLLAASDKKMPIAILNIGPTRADHLAELKVRGRCGEVLSVIQPL-----------
>tr|G3N9F5|G3N9F5_GASAC Uncharacterized protein OS=Gasterosteus aculeatus PE=3 SV=1
-----------------------------------DFVRASRLFVISGAGLSTESGIPDYRSEGVGLADRRP---MQHAEFVRSAKSRQRYWA--RNFVG
WPSRQPNSAHEALRKWE-QRGKLHWLVTQNVDALHSKTGHERLTELHGCAHRVLCLGCGDISPWRAFIEDVPSCENCGG--VLKPEVTFFGDTNKTVQFV
HDRLGESDAVLVVGSSLQVYSGYRFLLAAGDRKMPVAIVNIGSTRADHLAELKVIGRCAEVLSVMRPL-----------
>tr|I3KAE8|I3KAE8_ORENI Uncharacterized protein OS=Oreochromis niloticus GN=LOC100698520 PE=3 SV=1
-----------------------------------DFVRARRLFVITGAGLSTESGIPDYRSEGVGLADRRP---MQYAEFVRSAKSRQRYWA--RNFVG
WPSHQPNSAHKALQRWE-DRGKLHWLVTQNVDALHSKAGQKRLTELHGCAHRVTCLGCGAISAWRAFLEDVPSCDDCGG--ILKPEVTFFGDSNKTVQFV
HERLAESDAVLVVGSSLQVYSGYRFLLAARDREMPVAILNIGPTRADHLAELKVSGRCGEVLSVIQPL-----------
>tr|H2N065|H2N065_ORYLA Uncharacterized protein OS=Oryzias latipes GN=sirt4 PE=3 SV=1
-----------------------------------EFVRARRMLVITGAGLSTESGIPDYRSEGVGLADRRP---MQHAEFVRSARSRQRYWA--RNFLG
WPSHQPNLAHRALRRWE-EGGKLHWLVTQNVDALHGKAGQKRLTELHGCAHRVVCLSCSAVTPWSAFLEDVPSCQNCGG--ILKPEVTFFGDTSKTVEFV
HGRLAESDSVLVVGSSLQVYSGYRFLLAASDRKLPVAILNIGPTRADHLAKLKVSGRCGEVLSAVQLL-----------
>tr|A0A060WA42|A0A060WA42_ONCMY Uncharacterized protein OS=Oncorhynchus mykiss GN=GSONMT00069989001 PE=3 SV=1
-----------------------------------AFLRATRLFVITGAGLSTESGIPDYRSEGVGLADRRP---MQYAEYIRSAKSRQRYWA--RNYMG
WPSHQPNSAHLALQQWE-EQGKVHWLVTQNVDALHSKAGHQGLTELHGCAHRVLCLGCGAVSPWGAFIEDVPSCKDCGG--ILKPEVTFFGDTNRTVQFV
HERLAESDAVLVAGSSLQVYSGYRFLLAAADQKIPVAILNIGSTRADHLAEFRVSARCGEVLSVIQPH-----------
>tr|U9SW51|U9SW51_RHIID Uncharacterized protein OS=Rhizophagus irregularis (strain DAOM 181602 / DAOM 197198 / MUCL 43194) GN=GLOINDRAFT_339725 PE=4 SV
-----------------------------------NFFNNGKLLILTGAGVSTDSGIPDYRGPQGTYINYKP---IFYHEFAGQHRFRQRYWA--RSFLG
WPKTKPNSSHIAFTQLQ-SLGYIQNIVTQNVDGLHQKAGTKNILELHGTLHEVHCMQCGHIQKWKEDLPSYPSCDQCKK-GIYKPSIIFFGENKSVKLIA
SDMVKDCSAIMVVGSSLVTYSAFRLIKSAHDSGKNIVIINSGETRGDNLAWLKIEMLCGDILPLISQQITELI------
>tr|A0A0Q3X0X0|A0A0Q3X0X0_AMAAE NAD-dependent protein deacetylase sirtuin-4 OS=Amazona aestiva GN=AAES_17412 PE=4 SV=1
-----------------------------------HFVNSKRLFVITGAGISTESGIPDYRSEGIGLADRRP---MQHAEFIRSASARQRYWA--RNFVG
WPSFQPNTAHLVLRDWE-KLGKLHWLVTQNVDALHTKAGSQRLTELHGCTHRVFCLACGDQILWKAFLTXVPACCKCGG--ILKPDVTFFGDTCRKVNFV
HQRLAESDSMLVAGSSMQVYSGYRFALAARDKQLPIAILNIGPTRLDHFASLKLNARCGELLPLIVAPDPTS-------
>tr|C3YCU3|C3YCU3_BRAFL Putative uncharacterized protein OS=Branchiostoma floridae GN=BRAFLDRAFT_87444 PE=3 SV=1
-----------------------------------DFVTSKRLFVITGAGISTESGIPDYRSEGVGLADNRP---VQYADFLKSGAIRQRYWA--RNYVG
WPSFSPNISHETLSGWES-VGKLHWLVTQNVDSLHIKAGSRKVTELHGSAARVMCLSCP-VIPWHAFLAPVPECEKCGG--ILKPQIVFFGDNPKTVQFV
HKMLEESDAMLVAGSSLQVYSAYRFVSAARDQKKPIAVLNIGPTRGDKLADLKVSARCGDVLPQIHL------------
>tr|F6TVS6|F6TVS6_CIOIN Uncharacterized protein OS=Ciona intestinalis GN=LOC778889 PE=4 SV=2
-----------------------------------NFIKRRKLFVLSGAGLSTESGIPDYRSKDVGLANHKP---MQHQDFVKSADKRKIYWA--RSYLG
WAAWKPNAAHVKLAAMEK-DGRVEWHTTQNVDGLMVKAGAEQLTELHGQMRRVVCMRCN-LLDWSAFIREVPACRKCGG--DLKPNVTFFGDNPRKVTFV
RSIVDKCDGVLVVGSSLHVWSGYRFITQAHELGVPIAIVNVGETRADKFAAVKIDALCTDVFRAIE-------------
>tr|V9KXH6|V9KXH6_CALMI NAD-dependent ADP-ribosyltransferase sirtuin-4 OS=Callorhinchus milii PE=2 SV=1
-----------------------------------KFVRSKKLFVLTGAGMSTESGIPDYRSEAVGLAERRP---IQHSEFICSARARQRYWA--RNYIG
WPSHQPNVAHWVLSHWE-KLGKVHWLVTQNVDALHGKAESQRLTELHGCTHRVICLNCKDMTLWDEFLTDIPECQRCGG--ILKPDVTFFGDSNRKVNFV
HQRLAESDAILVAGSSLQVYSGYRFIVAAHEKKLPIALLNIGATRADALATLKIDARCGEVLSYLSESETFRLK-----
>tr|A7SK95|A7SK95_NEMVE Predicted protein OS=Nematostella vectensis GN=v1g190741 PE=4 SV=1
-----------------------------------EFIENPKIFVITGAGISTESGIRDYRSEGKGLANDRP---MEYQVFLKSAVMRQRYWA--RNYVG
WPSRQPNEAHYALAKLET-LGSVHSLVTQNVDALHTKAGSKNVIELHGCSHRVICLGCN-ITAWHAFLTSVPPCKACGG--ILKPEVVFFGDSPKIVNIA
YDRLAESDALWIIGSTVEVYSSYRFATEASKQGKPIAILNIGKTRADKLASLKVSGVCGTVLPKLDLLQRL--------
>tr|I1FX80|I1FX80_AMPQE Uncharacterized protein OS=Amphimedon queenslandica GN=LOC100633764 PE=4 SV=1
-----------------------------------SFIRSERLFVLCGAGVSTESGIKDYRSENVGLAKQRP---VNYSDFLNSSNVRQRYWA--RNTTA
WPSFKPNIAHRSLATLEH-LGKLHWLVTQNVDDLHHKAGSRQVTELHGTVFSVICLTCR-KLSWSAFVSETPTCRRCSG--ILKPDVVFFGDVPKRVEFV
SKRLAECDAMLIAGSSIETYSALRHVKQAKDLRVPVLILNIGRTRADPIADFIINAKCGDALTSVVEKMLKK-------
>tr|T1L486|T1L486_TETUR Uncharacterized protein OS=Tetranychus urticae PE=4 SV=1
-----------------------------------QFMSHSNIIVITGAGISTESGVPDYRSEKVGLANHKP---IQYQEFLSSQAVRLRYWA--RNFIG
FDKIRPNNAHYILSKWER-QEKIKWIVTQNVDQLHQKAGSLKVTELHGSGFTVKCLQCD-TISLVDDLDAVPRCPKCLG--ILKPDIIFFGDTPKRVEYI
YQKMDKCDALLVIGSSLQVYSAYRYIIAASEKSLPIMLINIGASRADNLKNVTIVRRAGQLLPLIEISS----------
>tr|N6TQF1|N6TQF1_DENPD Uncharacterized protein (Fragment) OS=Dendroctonus ponderosae GN=YQE_11882 PE=4 SV=1
-----------------------------------EFINSKKLLVLTGAGISTESGIPDYRSKEVGLENHKP---IQHIEFIKSATVRQRYWA--RNFVG
WFKSLPNSVHFSIRDLEIEDKIVHTVVTQNVDGLHLKAGSRNVIELHGTGYRVICLKCD-LYDDFEEIASPPICESCGG--VLKPDITFFGDNPKRVDLV
REKVSLSDRILVLGSSLSVFSGYRIILQALEEKKPVCIVNIGSTRADKLINLKIDAKCGDILPRIKS------------
>tr|A0A026WFF3|A0A026WFF3_CERBI NAD-dependent ADP-ribosyltransferase sirtuin-4 OS=Cerapachys biroi GN=X777_06650 PE=4 SV=1
-----------------------------------EFIGHNRLCILTGAGISTESGIPDYRSAEVGLANHEP---ILYKEFCNSEAARRRYWA--RNYVG
WPSIKPNITHKMLKDLEC-IRKVECIVTQNVDNLHSKAGSKKVIELHGTAFRVMCLNCD-KLCMTAELTQIPDCDKCGG--ILKPDIVFFGDNRRIVQNV
KANVENSDALLILGTTLTTFSAYRIVLQAVDIKKSIAIVNIGKTRADKLAHLRVEGRCGDILTKAWQPDIAIKS-----
>tr|E2BN27|E2BN27_HARSA NAD-dependent deacetylase sirtuin-4 (Fragment) OS=Harpegnathos saltator GN=EAI_15887 PE=4 SV=1
-----------------------------------EFIKHHQLCVLTGAGVSTESGIPDYRSAKVGLADHRP---IHYKEFCASEKTRRRYWA--RNFVG
WPSFKPNITHMILKDLEY-TGKIGFIITQNVDNLHSKAGCKKIIELHGTAFKVMCLNCS-KICMVTELSQIPACNNCGG--ILKPDIVFFGDNPHVVQNV
KTNVENSDALLILGTSLSTFSAYRIVLQAIDAKKPIAIINIGKTRADELVNLRVEGRCGDIFPKV--------------
>tr|W4W1S3|W4W1S3_ATTCE Uncharacterized protein OS=Atta cephalotes PE=4 SV=1
-----------------------------------EFVRYHHLCVLTGAGISTESGIPDYRSAEVGLANHKP---VLYKEFCDSEAIRRRYWA--RNYIG
WPSLKPNITHKILKHLEY-VGKVGCIITQNVDNLHLKAGSKKVIELHGTAFRVMCLNCD-KISMIAELTQVPACNNCGG--ILKPDIVFFGDNLHKVQNV
KNNVENLDALLVLGTTLSTFSAYRIVLQAIDAKKPIAIVNIGETRADKCINLKVEGRCGDILPKIWQLNISKDY-----
>tr|E9J587|E9J587_SOLIN Putative uncharacterized protein (Fragment) OS=Solenopsis invicta GN=SINV_07456 PE=4 SV=1
-----------------------------------EFVKHHRLCVLTGAGISTESGIPDYRSAEVGLANHKP---ILYKEFCDSKASRRRYWA--RNYIG
WSSIKPNITHKILKHLED-IGKVECIVTQNVDNLHLKAGSKKVIELHGTAFRVMCLNCD-KICMMAELSQVPACDNCGG--ILKPDIVFFGDNPHKVQNV
KANVESLDALLILGTSLSTFSAYRIVLQAVDAKKPIAIVNIGETRADKCINLKVEGRCGDVLSKIWQLNASKDF-----
>tr|A0A0C9PWP9|A0A0C9PWP9_9HYME Sirt4 protein OS=Fopius arisanus GN=Sirt4 PE=3 SV=1
-----------------------------------NFINSGRICVLTGAGVSTESGIPDYRSQGVGLANKRP---VLYQDFRNKEYVRRRYWA--RNYIG
WPKVRPNVTHKVLKHLED-LGIVNCIVTQNVDSLHWKAGSKNVIELHGTAFKVMCLGCD-LINVIAELSELPPCENCGG--ILKPDIVFFGDNPRVVENV
RVSVDESDALLVLGTSLTTFSGYRIILQAVDNNKPIAIVNIGETRADCHAHVKIKSRCGEVLSNIFPSHDFNRS-----
>tr|A0A088A4P0|A0A088A4P0_APIME Uncharacterized protein OS=Apis mellifera GN=Sirt4 PE=4 SV=1
-----------------------------------DFISHDNICVLTGAGISTESGIPDYRSEGVGLANHKP---VLYKDFCNSDAIRRRYWA--RNYIG
WPSIKPNNTHKILTKLEN-ANKIRYIITQNVDNLHTKAGSKKVIELHGTAFRVMCLNCN-RICMTVELTQVPICEKCDG--ILKPDIIFFGDNPRIVENI
KYNIEHSDSLLIIGTTLTTFSSYRIALQANNIGKPIAILNIGKTRVDNLAKIKVEGRCSNVLSKIYSMLN---------
>tr|E2ADS2|E2ADS2_CAMFO NAD-dependent deacetylase sirtuin-4 OS=Camponotus floridanus GN=EAG_10407 PE=4 SV=1
-----------------------------------EFIKHHRLCILTGAGISTESGIPDYRSAEVGLANHKP---ILYKEFCNSEAIRRRYWA--RNYVG
WPSLKPNITHEILRDLEY-VGKVECIVTQNVDNLHSKAGSKKVIELHGTAFRIMCFNCD-KIYMVAELSQVPACDNCGG--ILKPDIIFFGENPRIVEKV
KNNIENSDALLILGTSLATFSSYRIVLQAVEANKPIAIVNIGKTRADEFMNLKLEGRCGDILSKVWQLNASNNS-----
>tr|E0VUA2|E0VUA2_PEDHC NAD-dependent deacetylase sirtuin-4, putative OS=Pediculus humanus subsp. corporis GN=Phum_PHUM448760 PE=4 SV=1
-----------------------------------NFMKNSSVAVLTGAGVSTESGIPDYRSE-TGLKKYRP---IDYSTFLKNKAARIRYWA--RNYVG
WPSKEPNGTHFALQLYEA-AGKVSGIITQNVDGLHHKASGHNIIELHGNAYWVKCLSCK-LIFVQEEIDEIPDCEKCGG--ILKPTIVFFGDNPKTVKKA
ENLIESSDALLVMGTTLSTLSSLRIVTQAFDLCKYICIVNLGETRGDKMADIVINAKCSEILPNYNRELHAYRS-----
>tr|A0A0M8ZU10|A0A0M8ZU10_9HYME NAD-dependent protein deacetylase Sirt4 OS=Melipona quadrifasciata GN=WN51_05158 PE=4 SV=1
-----------------------------------DFISHSNICVLTGAGISTESGIPDYRSEGVGLANRRP---VLYRDFCNSADIRRRYWA--RNYVG
WPSIKPNSTHQILKKLED-LNKVRCIVTQNVDNLHTKAGSRKVIELHGTAFRVMCLSCN-RICMTADLSQVPSCKNCSG--VLKPDIIFFGDNPRVVESV
RYNIEHSDSLLILGTTLTTFSGYRIALQASHAKKPIAILNIGKTRADNLAEIKVKGRCGDVLARIYSMIDQREE-----
>tr|J9K8C7|J9K8C7_ACYPI Uncharacterized protein OS=Acyrthosiphon pisum PE=4 SV=2
-----------------------------------RFIEHKKILVLTGAGISTESGIPDYRSADVGLAKNRP---VIYQQFIKNPEVRIRYWA--RNYVG
WPSMSPNYAHKFLKNLED-KNKIVHIITQNVDNLHTKAGSKNVLELHGTAYVVHCLKCD-TIDVSIELTPVPECPKCQGN-LLIPRIVFFGDNPKRVQRV
NDFVEECDSLLVMGSSLFVYSGYRIVLGTKSANKPVAVVNIGPTRADDCVDFKIEARFGEILPLLSP------------
>tr|A0A024TQV8|A0A024TQV8_9STRA Uncharacterized protein OS=Aphanomyces invadans GN=H310_10661 PE=4 SV=1
-----------------------------------ELVKSKKILVLTGAGISTESGIPDYRSAGVGLANHRP---IQHMDFMTSAATRQRYWA--RNFMA
RGAVQPNTNHNILARWQESGRWDVTIVTQNVDRLHTKAGSRHVIELHGSSEEVLCMGCAAPIDYEDFLTQVAVCPYCGQA-MYKPNIVFFGDSPKKVDQI
YETVRQSDAMVVLGSSLHVFSGYRFAMRAKEWNIPLAIVNIGPTRADPLATLKLDAKCSAVLSQLNLT-----------
>tr|A0A067C2H3|A0A067C2H3_SAPPC Uncharacterized protein OS=Saprolegnia parasitica (strain CBS 223.65) GN=SPRG_13318 PE=4 SV=1
-----------------------------------EMLHASKVVVLTGAGISTESGIPDYRSKGVGLANHKP---IEHRDFMNHEAVRQRYWA--RNYMA
RHGAQPNANHVVLAQWQHDSRGDVRLVTQNVDRLHQKAGARDVIELHGSMDEVCCMACDAAMAFVEYLSTVAHCPLCRVG-FYKPNVVFFGDSAPTVQQI
YHDVDTADAMLVLGSSLHVFSGYRFLLRAKDAHVPIGIVNIGPTRGDGLATVKVNAKCSSVLSELHLV-----------
>tr|W4GL75|W4GL75_9STRA Uncharacterized protein OS=Aphanomyces astaci GN=H257_07017 PE=4 SV=1
-----------------------------------ELLKSKKVVVLTGAGISTESGIPDYRSEGVGLANHRP---IQHMDFMTSAATRQRYWA--RNFMA
RDAVQPNANHRVLSQWQNSGLWDVTLVTQNVDRLHTKAGSRDVIELHGSSEEVRCMGCAAPIDYQDFLSPVAVCPYCGHA-MYKPNIVFFGDSPTKVDMI
YDAVKQSDAMLVLGSSLHVFSGYRFARRAAEWKVPLAIVNIGPTRADPIATLKLDAKCSTVC-----------------
>tr|E9G957|E9G957_DAPPU Putative uncharacterized protein OS=Daphnia pulex GN=DAPPUDRAFT_223174 PE=3 SV=1
-----------------------------------VLISSTNVLILTGAGLSTESGIPDYRSESVGLANHRP---IQHQDFMKFKHVRQRYWA--RNFVG
WPNVQPNASHGILADWER-QGKISSIITQNVDRLHHKAGSKAVVELHGCAHEVKCMKCN-EISLSVELSQIPHCQQCRDNGFFKPNIVFFGDNPKRVEFV
FSQLQSSDCLLVLGSSLHVYSGYRFIVRASELGIPSAIVNIGPTRGDKFASVKLNAKCSEVLKKICI------------
>tr|A0A0P5II33|A0A0P5II33_9CRUS NAD-dependent protein deacetylase sirtuin-4 OS=Daphnia magna PE=4 SV=1
-----------------------------------MLVSSTNILILTGAGVSTESGIPDYRSELVGLANHRP---IQHQDFMRSKHVRQRYWA--RNFVG
WSTVQPNASHFLLASWER-HGKISSIVTQNVDRLHHKAGSKATVELHGCAHEVKCMKCN-EMSLSVELSQVPNCQQCRDEGFYKPNIIFFGDNPKRVEFV
FSQLQSSDCLIVLGSSLYVYSGYRFILRASELGIPSAIVNIGPTRGDKLASIKLSAKCSEVLTKICINPYLLKT-----
>tr|E0XV36|E0XV36_9GAMM NAD-dependent protein deacetylases, sir2 family OS=uncultured Chromatiales bacterium HF0200_41F04 PE=4 SV=1
-----------------------------------YLISSRRITIFTGAGISTKSGIPDFRSPKGLWK-LQP---IQYQDFVASPEMRREAWR--RKIVI
DERASPNRGHRAVAELV-KSEKCRTVITQNIDGLHQASPEQNIVELHGNGTYAVCLECGLRHE---FDR-LPICRRCN--GIVKAATVSFGQSPEAMRRS
EQSSLECDLFIVLGSSLVVFPAAAFPKIAKSNGALLVIVNHEETDQDGIADLTIHREIGQVLGDATNVD----------
>tr|C1MHV1|C1MHV1_MICPC Histone deacetylase OS=Micromonas pusilla (strain CCMP1545) GN=MICPUCDRAFT_50331 PE=4 SV=1
-----------------------------------SFIAAERLLVITGAGCSTESAIPDYRSPKGAYTGFKP---MTHQDFLRADGNRKRYWA--RSFVG
WKETSPNRAHVALAALQ-REGHVWRLITQNVDRLHHAAGSEDALELHGTTHEVICLNCDDVTPFLGELDGLPTCLKCGT-GTLKPKVVFFGDCPADASVA
KAWSERADAVLVVGSSVSTFSAYKLVKEAVTRGAPVAILTNGDTRVDDVADLKVRAVAGETLSRILDVVRREET-----
>tr|C1EAC1|C1EAC1_MICSR Histone deacetylase, SIR2 family OS=Micromonas sp. (strain RCC299 / NOUM17) GN=MICPUN_60020 PE=4 SV=1
-----------------------------------SFISKERLLVITGAGCSTESNIPDYRSPTGAYSGFKP---MTHQDFLKTEANQRRYWA--RSFVG
WRETAPNDAHRAIAELQ-RESNVWRLITQNVDRLHQVAGAEDVLELHGSTHDVQCLACGAVSCLAAELDGVPPCEKCKH-GPLKPAVVFFGDGPLTAEEA
RRASDGCDGVLIVGSSVSTFSAFRLVRDAHVRGVPVAVLTCGWTRVDEMASVKVEKLAGEVLPRVVERLRREEL-----
>tr|A0A0G4ESR1|A0A0G4ESR1_9ALVE Uncharacterized protein OS=Vitrella brassicaformis CCMP3155 GN=Vbra_13272 PE=4 SV=1
-----------------------------------DFLETQRLQVITGAGCSTESGIPDYRGPTGSYRGHRP---IQHDEYIFNPWSRQRYWA--RSMFG
YGLAKPNDAHIALARLE-AAGAVEGIVTQNVDRLHQKAGSRNVLDLHGRSDRVVCMNCGHQLSWIGNLDDVPTCQRCG--GMLKPAVIFFGDVSPIKRQV
NKQVENAEGLLVVGSSLEVFSAYRLVKLALDREVPVAIVNKGVTRLEREMVLKLDARAGHILKGLERRALQRGG-----
>tr|A0A0K1LPP1|A0A0K1LPP1_9CAUD NAD-dependent deacetylase OS=Escherichia phage Murica GN=CPT_Murica76 PE=4 SV=1
----------------------------------------RRLIIISGAGLSAESGIPTFRSGTAMWENFSIDEVCNIHTFAKNYYKVHDFYNARRVALG
--SVDPNLAHLRIAEWYSRWSGRVINLTTNVDDLLERAGVKDILHVHGYLPEITYEDAEGNVIKNIGYTE----VDTGKYTWVKPNVVFFGEVAPKMYDL
LTSLTSNDMVILVGCSNTVINFNWELFPATCKGTKLLIVNKYDSQSISRSDLYQYNGAVDAFKAFIET-----------
>tr|R9TG77|R9TG77_9CAUD Sir2 family NAD-dependent protein deacetylase OS=Vibrio phage nt-1 GN=VPFG_00091 PE=4 SV=1
----------------------------------------MRIFIFSGAGLDAESGISTFRDANGLWENHDIMQVCNINTFRDNYELTHKFYNQRRKQLA
--DVHPNSAHFKIAELCEKYDV--DNYTANVSDLLERAGCKDVKHIHGELTKIELDYADRDVTIDIGYTE----HKLRDHHYDKPAVVFFNEGAPMFWGA
IDTLLPSDIAIVVGSTLEINPIHWD-LGTTG--CKFILINPTGIDTIRMCDVFINKPATEAF----DE-----------
>tr|K9GQ66|K9GQ66_9PROT NAD-dependent protein deacetylase of SIR2 family OS=Caenispirillum salinarum AK4 GN=C882_1794 PE=4 SV=1
----------------------------------------PQLMILSGAGLSAESGIRTFRDAGGLWEGHDIDTVCNFDNWRDNLELVHGFYQARREAAA
--KADPNPAHDAVARWQTRWPT--HILTQNVDDLLERAGCTDVCHLHGRLQDMRCYDCDYE--WEHGLGPWTACPDCGSTRGVKPGVVFFGEMAPELQRA
MDSLRPRDVLLVVGTSGQVLPVARMGLEAPG--P-TILNNLEPSDVDRCFDHTLYRPAGEAV----AE-----------
>tr|V9LZF1|V9LZF1_9CAUD NAD-dependent deacetylase OS=Vibrio phage VH7D PE=4 SV=1
----------------------------------------MRIFIFSGAGLDAESGISTFRDANGLWENHDIMEVCNINTFANNYEVTHRFYNERRKQLA
--EVHPNSAHYKIAELCEKYDV--DNYTANVSDLLERAGCKDVKHIHGELTKIVQDYTSKDTVIDIGYNE----YELRTGRRDKPGVVFFNEGAPLFWGD
IDTLLPTDIAIVVGSTLEINPIHWD-LSATG--CKFILINPTGIDTIRMCDVFINKPATEAF----DE-----------
>tr|I7HPE6|I7HPE6_9CAUD Phi92_gp038 OS=Enterobacteria phage phi92 GN=PHI92_gene_038 PE=4 SV=1
----------------------------------------RRVIFVSGAGLSADSGIRTFRTDRALWEEWDLEEICDIGAFQALYAKTHEFYNKRRVELK
--DVQPNAAHIQIAKWFKEYPN-VVNLTTNVDDLLERAGVDSVIHVHGYLPEVVYRMHGDYTLVDIGYNS----INIDDYNWVKPNVVFFGEAAPLMAHL
FDTLTMQDLVVVVGCSNQVINFNWELFPALNMGTKMIVVNPG----INYEETLLYEKAADAFPAFIKM-----------
>tr|K7QKA1|K7QKA1_9CAUD Putative Sir2-like protein OS=Escherichia phage phAPEC8 GN=phAPEC8_0072 PE=4 SV=1
----------------------------------------RRLIVISGAGLSADSGVRTFRTDKALWDEYDLSEVCDIFNFRALYRKTHDFYNKRRVEMD
--SVSPNAAHYQIAEWFQEYGCDVINITTNVDDLLEQAGVVDVLHVHGFLPEVIVD----NIIKDVGYAA----IDVDDYKYVKPNVVFFGETAPLMYHI
LDGLTAQDMVIVVGCSNQVINFNWELFPALNIGTKMVVVNPG----VNYEETLLYEKAATAFEGFIKM-----------
>tr|A0A0A7RSS8|A0A0A7RSS8_9CAUD Putative Sir2-like protein OS=Enterobacteria phage DT571/2 GN=sir2 PE=4 SV=1
----------------------------------------RRLIIISGAGLSVESGVRAFRTDKALWDDYDLEEVCNIHAFRGFYHKTHTFYNKRREELE
--TVEPNLAHLRIGEWYKKYPGQVVNLTTNVDDLIERAGVPDILHIHGYLKEVVVADSSSNRIIDVGYNS----IDPDDYKWVKPNVVFFGEHAPAMYNI
FDGITSQDMIIMVGCSNQVINFYWELFPVLNLTAKLMVVNYYDSALMTRSEMYQLKGAVDAFPDFIAR-----------
>tr|G0X4Y9|G0X4Y9_9CAUD Putative Sir2-like protein OS=Salmonella phage 7-11 PE=4 SV=1
----------------------------------------PNLIVVSGAGLSVASGVRAFRTDKAMWDEYDLEEVCNIQAFRGFYHKTHTFYNKRREELG
--TVEPNVAHLRIAEWFERYKGRVKNVTTNVDDLLERAGIPEVIHVHGRLNYLRYKLEGSEQCVNIGYTQ----IEPDDYHWCKPDVVFFGELAPKMYNV
FDDIMPDDIIILVGASNQVINFIWDLFPAINRGAKLVVVNPQ----IDMSERYQMTTAEDAFPEFLAL-----------
>tr|J9QNX7|J9QNX7_9CAUD Sir2-like protein OS=Pectobacterium phage My1 GN=My1_098 PE=4 SV=1
----------------------------------------RRLIVISGAGLSVESGIRAFRTDKAMWDEYDLEEVCNISAFRGFYGTTHEFYNKRRQELE
--TVEPNLAHLRIAEWFNRFSG-VVNITTNVDDLIERAGVPEVLHVHGYLKELVVETEGDRRIVDVGYNA----INPDDYGWCKPNVVFFGEMAPEMYGI
LDTLTANDMVILVGCSNTVINFNWELLPAARRGTKVHIVNPM----INYLEQEGYAGAVEVFPTFLRT-----------
>tr|V5KSM6|V5KSM6_9CAUD Putative Sir2-like protein OS=Enterobacteria phage 4MG GN=4MG_107 PE=4 SV=1
----------------------------------------RRLIVISGAGFSAESGVRTFRTDKALWDEYDLEEVCNIHAFRGFYHKTHMFYNKRRVELQ
--TVHPNAAHMRVAEWYKNYPKQVVNLTTNVDDLLERAGVPDTLYIHGYLKELRYKLHDSEQLVDIGYNE----VDPDEFHWCKPNVVFFGEAAPALYST
LDSLTSEDMVIVVGCSNTVINFNWELFPASRMGTKIVVVNPN----VRYDEQLMYTGAVDAFPGLIKM-----------
>tr|K4IF08|K4IF08_9CAUD NAD-dependent protein deacetylase of SIR2 family OS=Salmonella phage SSE-121 PE=4 SV=1
----------------------------------------RRLIVISGAGFSAESGVRTFRTDKALWDEYDLEEVCNIHAFRGFYHKTHMFYNKRRAELP
--TVHPNLAHLRVAEWFQRYPGQVVNLTTNVDDLLERAGVPDTVYIHGYLKEIIVKDNKGKEIIDVGYNE----VDPDQYKWCKPNVVFFGEFAPEMYDI
LDTLTNEDMVIVVGCSNTVINFNWELFPAVRRGTKVLVVNPR----INYLEQEQYCGAVEAFNNFIKI-----------
>tr|A0A0A0RPK9|A0A0A0RPK9_9CAUD Sir2-like protein OS=Salmonella phage Stitch GN=CPT_Stitch109 PE=4 SV=1
----------------------------------------RRLIVVSGAGLSVDSGVRAFRTDKSLWDEYDLEEVCSLPNFEALYLKTHEFYNMRRQELQ
--TVEPNIAHLRIAEWFQRYGADVKNFTTNVDDLLERAGIPEIIHAHGYLKEVIYRQG-RNIIEDVGYTA----IAPEDYEWVKPNVTFFGETAPWQINL
FDTLTSNDMVIVVGCSNQVIDFNWELFPAVCRGTKMMVVNPQ----VRYDEQLEYAGAAEVFKHFIDQ-----------
>tr|A0A0P4VPP7|A0A0P4VPP7_9HEMI Putative sirtuin 5 OS=Rhodnius neglectus PE=2 SV=1
----------------------------------------KNIVVLTGAGISAESGIPTFRGPGGFWRTYRSQDLASVGAFKRNPSLVWEFYHYRRELVL
--NKQPNKAHIALAEAEKRLGRRLTVITQNIDGLHQRAGSKEVVELHGSLYKTLCLKCHTMDTGRGDLEDLPRCKNNNCKGLLRPYIVWFGENLH-EDTL
SYELDLCDACLIVGSSSVVYPAAMYAPTLAARGIPVAEFNLESTAATHLFKFHFEGPCTETIPEVLKDIYD--------
>tr|A0A091EEL1|A0A091EEL1_FUKDA NAD-dependent deacetylase sirtuin-5 OS=Fukomys damarensis GN=H920_04800 PE=3 SV=1
----------------------------------------KHIVIISGAGISAESGIPTFRGAGGYWRKWKAEDLATPMAFARNPSRVWEFYHYRRSIIL
--TKEPNAGHRAIAECEARLSRRLLVITQNIDELHRRAGTKNLLEIHGTIFKTQCTSCGSVVENYKNLEELPRCEVAGCGGLLRPHVVWFGENPAILEKA
SRELELCDLCLVVGTSSVVYPAAMFAPEVAARGVPVAEFNTETTPATDRFSKGRRGSD---------------------
>tr|W5FVG0|W5FVG0_WHEAT Uncharacterized protein OS=Triticum aestivum PE=3 SV=1
--------------------------------------KSNKLMVLTGAGMSTESGIPDYRIPNGAYSGFKPL---THQEFVRSIRRYWARSYAGWRRFR
--RAQPNTAHYALASLERI-GRVHTMVTQNVDRLHHRAGSK-PVELHGSVYEVICLDCGTSISRALQDFDIPSCSQCGG--VLKPDVVMFGDVPREADSA
KEAARNCDALLVVGSAVMTMSAFRLARLAHEANAPIAAINIGGTRADSIISLKINARCGEILPRVLQMG----------
>tr|A0A0K9PWW0|A0A0K9PWW0_ZOSMR NAD-dependent protein deacetylase SRT2 OS=Zostera marina GN=ZOSMA_146G00280 PE=3 SV=1
--------------------------------------QSHKLAVLTGAGISTESGIPDYRSPNGAYSGFKPI---THQEFVRSNRRYWARSYAGWRRFN
--AAQPSAAHRSIASLEKA-GRIHFMITQNVDRLHHRAGSA-PLELHGTVYSVVCLNCGTAIDRAEDNFDVPCCNKCNG--LLKPDVVFFGDVPKDATEA
MNAAKGCDSFLVLGSSLMTFSAFRLARAAFDSGASIAIVNVGKTRADDFVPLRINARVGEVLPRVIEVG----------
>tr|A0A022Q0C8|A0A022Q0C8_ERYGU Uncharacterized protein OS=Erythranthe guttata GN=MIMGU_mgv1a006842mg PE=3 SV=1
--------------------------------------RSSKLVVLTGAGISTESGIPDYRSPNGAYTGFRPI---THQEFIRYSRRYWARSYAGWRRFN
--AAQPGPAHIALASLEKA-GRIDFMMTQNVDRLHHRAGSN-PLELHGTVYVVACTECGFSLPRAEEEFHIPTCDKCNG--VLKPDVVFFGDVPKGADRA
MKAAKECDAFLVLGSALMTMSAFRLIKAAHEGGAATAIVNIGATRADDFVPLKIQARLGEILPRLLSVG----------
>tr|K4BP99|K4BP99_SOLLC Uncharacterized protein OS=Solanum lycopersicum GN=Solyc04g009430.2 PE=3 SV=1
--------------------------------------RSTKLVVLTGAGMSTESGIPDYRSPNGAYTGFKPI---THQEFLRSIKRYWARSYAGWRRFT
--AAQPSTGHIALSSLEKA-GHISFMITQNVDRLHHRAGSN-PLELHGTVYIVACTNCGFSLPRAEEDFYIPECQSCQG--VLKPDVVFFGDVPKSADAA
MEAAKGCDAFLVLGSSLMTMSAFRLIKAAREAGAATAIINIGATRADDIVPLKISARVGEILPRLLNVG----------
>tr|M0TA83|M0TA83_MUSAM Uncharacterized protein OS=Musa acuminata subsp. malaccensis PE=3 SV=1
--------------------------------------RSRKLVVLTGAGISTESGIPDYRSPNGAYTGFKPI---THQEFVRSSRRYWARSYAGWRRFL
--AAQPNAAHRALASLEKF-GRINYMVTQNVDRLHHRAGSD-PLELHGTVYSVVCLKCDNSINRAAEDFEIPNCQQCGG--ILKPDVVFFGDVPKDAEKA
KETARECDGFLVIGSSVMTMSAFRIVRAAYEANAAVAVINIGKTRCDEFVSLKINARCGEILPRVLEMG----------
>tr|A0A0Q0AZH2|A0A0Q0AZH2_PSESY NAD-dependent protein deacetylase OS=Pseudomonas syringae pv. syringae GN=ALO45_100417 PE=4 SV=1
--------------------------------------ADKPFLVVTGAGISTASGIPDYRDKDGVRRGKQPM---MYQEFLGNPARYWARAMLGWPRIR
--AAQANAAHRALAALQAK-DTITGLITQNVDALHAQAGSRDVIELHGSLHRVLCLDCQQRSERIGASFKVPNCPHCEGD-KLKPDVVFFGEVAAQAAKA
TQSVEEAEGLLVVGTSLMAWSAFRLCKAMAEQGKPVIAINHGKTRADELLEMKIEASCEQVLPWLAEQL----------
>tr|A0A0P9R770|A0A0P9R770_PSECA NAD-dependent protein deacetylase OS=Pseudomonas cannabina GN=ALO81_01266 PE=4 SV=1
--------------------------------------AEKSFLVVTGAGISTASGIPDYRDKDGVRRGKQPM---MYQEFLGNPARYWARAMLGWPRIR
--AAQPNAAHRALAELQGK-RAITGLITQNVDALHSQAGSHDVIELHGSLHRVLCLGCQQRSDRVGAAFKVPECPHCEGD-RLKPDVVFFGEVAAQAANA
TSSVAQAEGLLVVGTSLMAWSAFRLCKAMVEQGKPVIAINHGKTRADELLSMKIEAPCEQVLPWIAEHR----------
>tr|A0A0Q0KCW5|A0A0Q0KCW5_9PSED NAD-dependent protein deacetylase OS=Pseudomonas coronafaciens pv. zizaniae GN=ALO38_00406 PE=4 SV=1
--------------------------------------TDKAFLVVTGAGISTASGIPDYRDKDGVRRGKQPM---MYQEFVGNPARYWARAMLGWPRIR
--AAQPNAAHQALAALQAA-NVVNSLITQNVDALHTQAGSQDVIELHGSLHRVLCLDCQQRMDRSGAGFTVPACMYCQGE-RLKPDVVFFGEVAPQAASA
TSSVEQADGLLVVGSSLMAWSAFRLCKAMVEQGKPVIAINHGKTRADELLHMKIEASCEQVLPWLADKL----------
>tr|A0A0Q0E4Y3|A0A0Q0E4Y3_PSESI NAD-dependent protein deacetylase OS=Pseudomonas syringae pv. ribicola GN=ALO47_01901 PE=4 SV=1
--------------------------------------AERPFLVITGAGISTASGIPDYRDKDGVRRGKQPM---MYQEFVNNPARYWARAMLGWPRIR
--AAQPNAAHQALAHLQNG-HAITGLITQNVDALHTQAGSREVIELHGSLHRVLCLDCHQRHDRLGAGFKVPPCSHCQGN-RLKPDVVFFGEVAPPAAKA
MLSAEQAEGLLVVGTSLMAWSAFRLCKAMAEQGKPIIAINHGKTRADELLDMKIEAPCEQLLPVLAEEL----------
>tr|A0A0P9LYM0|A0A0P9LYM0_9PSED NAD-dependent protein deacetylase OS=Pseudomonas caricapapayae GN=ALO80_100449 PE=4 SV=1
--------------------------------------ADKPFLVVTGAGISTASGIPDYRDKQGVRRGKQPM---MYQEFVGNPARYWARAMLGWPRIC
--AAQPNAAHQALAALQAD-DVITGLITQNVDALHTKAGSRDVVELHGSLHRVLCLDCQQGSDRVGAGFKVPRCAYCHGD-RLKPDVVFFGEVAAQAAKA
TLSVEQAEGLLVVGTSLMAWSAFRLCKAVVEQGKPVIAINHGKTRADELLEMKIEASCEQALPWIAEQL----------
>tr|B4EF84|B4EF84_BURCJ Putative regulatory protein OS=Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 / CF5
--------------------------------------RHPRLLVLTGAGISTDSGIPGYRDRNGQWMRSPPI---QLHEFLGSDARYWARSMIGWPVVG
--RARPNGSHVALARLGGA-GRIERLVTQNVDGLHQRAGSDDVIELHGGINGVTCLDCGAHHARLGDTFRIPACPACGG--LLKPAVVFFGEVPREVALA
SQALDAADALLVVGSSLMVYSGYRFCVWAQAQHKPLAALNLGHTRADPILTLKVEAHCAPALDALVARL----------
>tr|A0A0P9QHL7|A0A0P9QHL7_9PSED NAD-dependent protein deacetylase OS=Pseudomonas syringae pv. delphinii GN=ALO72_100836 PE=4 SV=1
--------------------------------------AEKSFLVVTGAGISTASGIPDYRDKDGVRRGAQPM---MYQEFVGNPARYWARAMLGWPRIR
--ASQANAAHWALAALQAE-NLITGLITQNVDALHTQAGSEDVIELHGSLHRVLCLDCQQRSERADAGFKVPECPHCQGD-RLKPDVVFFGEVASHAARA
TLSVEQAEGLLVVGTSLMAWSAFRLCKAMAEQDKPVIAINHGKTRADELLQMKIEAPCEQVLPWLAERL----------
>tr|D7PD35|D7PD35_APLCA Sirtuin-5 OS=Aplysia californica PE=2 SV=1
--------------------------------------RAKHIVVLTGAGVSAESGVPTFRGAGGLWRKWRAQ---DPEAFADNPSLIWEFYHYRREVMS
--SKSPNPAHEAIAELKPL-GRRVVVITQNIDELHRRAGSENIQELHGNLFKTRCTKCGDVRVNAAPVEKLPRCQSCGG--LLRPHVVWFGELDQELRQT
SEELEKCDLCLVVGTSSVVYPAAMFAPQVAGRGVPVAEFNIEETPATDSFGFMFQGPAGQLLPRGPGCQ----------
>tr|T1KC96|T1KC96_TETUR Uncharacterized protein OS=Tetranychus urticae PE=3 SV=1
--------------------------------------QSKHIVAITGAGISAESGVPTFRGSGGLWRTFRAT---EPSAFERNPSLVWEFYSYRREVVL
--TKSPNPAHIALAELKGE-GRKLVIITQNIDELHHKAGSTNIIELHGTLFKTRCLKCGHVDSNEAPIHDLPHCKGCNG--LLRPNVVWFNELRSELQSA
EKEMSACDLVLVIGTSSAVYPAANLAPAAAARGVPVAEFNIEETSATNDFGFHFQGPCGKTLTAALAP-----------
>tr|A0A0F8AVU6|A0A0F8AVU6_LARCR NAD-dependent lysine demalonylase and desuccinylase sirtuin-5, mitochondrial OS=Larimichthys crocea GN=EH28_06066 PE=3 SV=1
----------------------------------------QNIAIITGAGVSAESGVPTFRGAGGYWRKWEAQRLATPEAFSRNPSRVWEFYHHRREVML
--TKNPNPAHLVIAECEERLGRTVTVITQNIDELHRRAGTKNLLEIHGNLFKTRCMSCGHEAKGKGDRDQLPRCEETGCHGLLRPAVVWFGET-LDSDIL
EKVLDSCDLCLVVGTSSIVYPAAMFAPQVAARGVPVAEFNMEDTPATMRFKFHFHGPCGTTLPLA--------------
>tr|L9LAM3|L9LAM3_TUPCH NAD-dependent deacetylase sirtuin-5 OS=Tupaia chinensis GN=TREES_T100000117 PE=3 SV=1
----------------------------------------KHIVIISGAGVSAESGVPTFRGAGGYWRKWQAQDLATPQAFARNPSRVWEFYHYRREVMQ
SKEKEPNPGHLAIAECEARLGRRVTVITQNIDELHRKAGTKNLLEIHVACLFNIIYFSAETQDAKIPVEKLPRCEEEGCGGLLRPHVVWFGENPDVLEEV
DRELALCDLCLVVGTSSVVYPAAMFAPQVSARGVPVAEFNTETTPATNRFRDK--------------------------
>tr|L5LI25|L5LI25_MYODS NAD-dependent deacetylase sirtuin-5 OS=Myotis davidii GN=MDA_GLEAN10017713 PE=3 SV=1
----------------------------------------NHIVIISGAGISAESGIPTFRGAGGYWRKWQAQTLATPEAFAQNPSLVWEFYHYRREVIQ
RV--KPNPGHLAIAECEARLRRRVMVITQNIDELHRKAGTKNLLEIHGSIFKTFAGKGAETQDARIPMEKLPRCEEAGCGGLLRPYVVWFGENSAILEEV
DKELALCDLCLVPCPPANQSDYMQINPTKMAAGCPNSELH-SEQQSFNYRRDK--------------------------
>tr|A0A084AZK5|A0A084AZK5_STACH Uncharacterized protein OS=Stachybotrys chartarum IBT 7711 GN=S7711_03231 PE=4 SV=1
--------------------------------------SSRRILALCGAGLSASSGLPTFRGAGGLWRNHDATSLATPGAFAHDPGLVWLFYGYRRHMAL
--RARPNAAHRALAALARVKGEGFLCLTQNVDNLSPRAGHEHLRLLHGSLFDIKCSNNG--CDWTADVTALPHCPACGT-GLQRPGVVWFGED-LDGAGI
DAWMGGVDLMLVVGTSATVYPAAAYIDEARARGARVVNVNPEAEDRWERLKEGDFGDAAEYLPILLKPLVGE-------
>tr|C7Z5C1|C7Z5C1_NECH7 Putative uncharacterized protein SRT2106 OS=Nectria haematococca (strain 77-13-4 / ATCC MYA-4622 / FGSC 9596 / MPVI) GN=SRT2106
--------------------------------------SSKRILALCGAGLSASSGLPTFRGAGGLWRNYDATTLATPTAFGQDPGLVWMFYGYRRHMAL
--NVKPNPAHYALAALAE-KNKDFLCLTQNVDNLSPRANHEQLRTLHGSLFDIKCSNGR--CDWIEDPEDIPKCPKCGK-GFQRPGVVWFNEG-LDMDGI
DNWLQKVDLMLVIGTSAKVWPAAGYIDQARDKGARVAVINMEAAKDRGDSNSKDFGDAAECLPLLLEPIIGK-------
>tr|A0A0G4P9Y5|A0A0G4P9Y5_PENCA NAD-dependent histone deacetylase, silent information regulator Sir2 OS=Penicillium camembertii GN=PCAMFM013_S009g000029 PE=4 SV=1
-----------------------------------GLMSCKRIVALLGAGISASSGLPTFRGAGGLWRSHDATSLATPEAFDETPGLVWQFYSYRRHMAL
Q--AEPNKAHYALAELSRR-NEDFITLSQNVDGLSQRANSKQLHLLHGTLFTVKCTNCNYIAEALVDKKDLPQCPECKD-GLLRPGVVWFGE-PLPTVDK
WIAAGPIDLCLVIGTSARIWPAAGYVHEARSQGARVAVCNMDPKDTPG---ELHYGDAGVIVPEILKSVIGE-------
>tr|A0A0A2V973|A0A0A2V973_BEABA NAD-dependent lysine demalonylase and desuccinylas e sirtuin-5 OS=Beauveria bassiana D1-5 GN=BBAD15_g10326 PE=4 SV=1
---------------------------------------SRRVLILCGAGLSVASGLPTFRGADGYWRHHDATRLATMQAFRTDPGLVWLFYGYRRHTCL
--KAQPNAGHRALAALAKA-KPNVLCLSQNVDDLSQRAGFQNLHTLHGSLFNIKCSNCESLIEASRDAPPLPKCPQCNT-GLQRPGVVWFGEMPNMMASI
ESWLDKVDLMLVIGTSTQVYPAAGYIDEARDRGAVVAVINPDAENGPNDFA---FGQDSTCLPVLLEPIIGKAQ-----
>tr|A0A074T7D9|A0A074T7D9_HAMHA Histone deacetylase SIR2 OS=Hammondia hammondi GN=HHA_227020 PE=4 SV=1
----------------------------------DDVRKAKYVVALTGAGVSAESGIPTFRDPDGLWKKYDPTVYATIWGFWRYPHKILDF-------MR
TNDPMPNAAHVALTDLQRL-GYLKFIVTQNVDNLHQDSGSTNVIEYHGSLLSATCRQCGKKMPLSKSMLQKDLPPKCACGGIFKPDVILFGEIPANVRDA
NREVDKCDLLLVVGTSASVSPASGLPYRAMRGGAKVVEVNLETTGLTNKFVQGRAS-----------------------
>tr|A0A0D2VL79|A0A0D2VL79_CAPO3 Uncharacterized protein OS=Capsaspora owczarzaki (strain ATCC 30864) GN=CAOG_008579 PE=4 SV=1
----------------------------------EFIEQAPKIVVLTGAGISTESGVPDYRSPVGLYVTSSHTQFREFRRYWARNYAA--F-------PS
FAQTRPNISHDVLARLEET-GKINFIITQNVDSLHSHAGSKHVLELHGNGSEVVCLSCRDRTRRSDLQVAFQFPDCSKCGGLLKPDVVFFGEVPAEVELA
RQKIRDADALLVVGSSLTVFSGFRFAKYAQELGKPIGIINIGATRADDFKIESHIG-----------------------
>tr|W4XLT3|W4XLT3_STRPU Uncharacterized protein OS=Strongylocentrotus purpuratus GN=Sp-Sirt4 PE=3 SV=1
----------------------------------HFVDKSKRLFVLTGAGISTESGIPDYRSDVGLYARSDRIQYRDFQRYWARNYVG--W-------PQ
FSSFLPNQSHLVLAEWEKV-GKIHWLVTQNVDALHTKAGSRCLTELHGCSNRIICMNCKTLTSRNALQEPFQVPSCESCGGLLKPHLVFFGDVDPEKEFV
FQRLEESDSVLVIGSSLEVYSGYRFVHTAWQQKKPIAIVNIGRTRADKLKIEGRLG-----------------------
>tr|M1WGC8|M1WGC8_CLAP2 Related to NAD-dependent histone deacetylase OS=Claviceps purpurea (strain 20.1) GN=CPUR_08365 PE=4 SV=1
---------------------------------------SRRILALCGAGLSASSGLPTFRGPGGYWRNHDATKLATMRAFMTDPGLVWLFYGYRRHSCL
--RAQPNAGHRALAALAKAN-TDFFCLTQNVDDLSQRASHDQLFPLHGSLFDIKCTTED--CDWVQHVSELPRCPKCKT-GLQRPGVVWFGESLHIVDQI
NDWVDNIDLMLVVGTSAQVYPAAGYIAKARLHGARIVTINPEAED-EAEMHKVRFGDAATCLPKLLEPIIGKMKD----
>tr|A0A0L0FR79|A0A0L0FR79_9EUKA Uncharacterized protein OS=Sphaeroforma arctica JP610 GN=SARC_08287 PE=4 SV=1
--------------------------------------CKSGIVFLTGAGISEASDIPTFRDPEGVWAKHDPREVGTRMAFQNHPERLWRILLEMVG--P
DNSPIPNAGHSALGELEK-YGYASTIITQNVDDLHEQSGNNNVIHLHGNLWSTECIVCGTPGDTTRDKDLPPRCKKCAQKGVLKPDAVLFGEILNILASA
VSAMENTPLLFVLGTSARVSPATDLPVIASNAGAKVVEINMEETQLTHTCVDYLHAPLETVLPQIVE------------
>tr|A0A0L0FNU2|A0A0L0FNU2_9EUKA Uncharacterized protein OS=Sphaeroforma arctica JP610 GN=SARC_09063 PE=4 SV=1
--------------------------------------AKGNLVFLTGAGMSAASDIPTFRDPDGVWATRDPKQCGTKEAFVHHPERLWTVLMDVVG--P
ENDPKPNLGHKALGDLEA-LGFTSTVVTQNVDDLHENAGNKDVMHLHGNLWRTFCVACGLQGTNTRTVDLPPRCDHCH--GVLKPDAILFGELLDIVDRA
SDLVKHTPLLFVLGTSARVTPASDFPIMAANHGAKVVEINMERTQLTDTCVDVMNEPLEVVLPQIVE------------
>tr|A0A067TC06|A0A067TC06_9AGAR Uncharacterized protein OS=Galerina marginata CBS 339.88 GN=GALMADRAFT_153142 PE=4 SV=1
----------------------------------------GNVAILTGAGVSVDSGIRAYRGEDGRYMN-P--------NY--KPIFYHELVDSRRSYLG
YPDAQPNTTHFALAALQHT-SYVSRIITQNVDGLHHKALQDNILELHGTLHRVHCNR-GHVFNWRQDVAIVPECPDCLLNSVHKPGVVFFGEIPKAVERS
FHDVEDSDRLLIIGTTLATYSAFRLLKHALEHKKPVMVLNVGPTRADSLPGEKLDVPSGAIMRDVARMAIGA-------
>tr|W4K0J3|W4K0J3_9HOMO Uncharacterized protein OS=Heterobasidion irregulare TC 32-1 GN=HETIRDRAFT_323334 PE=4 SV=1
----------------------------------------GNVAVLTGAGVSVDSGVKAYRGKDGRYMN-P--------NY--KCVIYHQLVEDRRSYIG
YPTTLPNPTHFALAALQHT-SVVTNLITQNVDGLHHKAIKAGILELHGTLHKVHCNH-GHGMDWAEDVALVPDCPSCLDNDTLKPDVIFFGEISKEVDRS
YNIIEECDRVFIMGTTLATYSAFRLLKHALELQKPVLFVNVGPTRADGLPGEKLDVPSGLVMRDVVKAVV---------
>tr|B0CTZ4|B0CTZ4_LACBS Predicted protein OS=Laccaria bicolor (strain S238N-H82 / ATCC MYA-4686) GN=LACBIDRAFT_244755 PE=4 SV=1
----------------------------------------GATTVLTGAGVSVDSGIKAYRGQDGRYMN-P--------NF--QPIFYHELIDERRSYLG
YPNAVPNVSHISLAALQHA-SVVPNIITQNVDGLHQKALRDAILELHGTLHRVSCNK-GHTIHWDADVAIVPDCSTCLLNAIHKPEVIFFGEIPQNVERS
FREVERCDQLLLIGTTLATYSAFRLVKHALELKKPVMLLNIGPTRADGIQEQKLNIASGVVLREVAKEIMFV-------
>tr|A0A0D7AJ06|A0A0D7AJ06_9AGAR DHS-like NAD/FAD-binding domain-containing protein OS=Fistulina hepatica ATCC 64428 GN=FISHEDRAFT_36187 PE=4 SV=1
----------------------------------------GNTAVLTGAGISVDSGIRAYRGKDGRYMN-P--------NY--KPIFYHELVDERRSFLG
YPDAQPNTSHYALAALQCS-SHVSRIITQNVDGLHHKAIQHNVLELHGTLHRVRCSH-GHLVDWQADVAVVPDCPRCLFNSVFKPEVIFFGEIPEEWEKS
YHDIEVCDRLLLIGTTLATYSAFRVLRHAQQLHKPVLVINVGPTRADGVEGERIDMPSGAILRQVATHLAYV-------
>tr|A0A0D0AJU6|A0A0D0AJU6_9AGAR Unplaced genomic scaffold GYMLUscaffold_153, whole genome shotgun sequence OS=Gymnopus luxurians FD-317 M1 GN=GYMLUDRAFT_51162 
----------------------------------------GNVTLITGAGVSVDSGIRSYRGADGRYIN-P--------NY--KPIFYHELTSERRSYLG
YPDSLPNTTHFALAALQYS-GVIPRIITQNVDGLHHKALQDSILELHGTLHRVRCKH-GHITDWKQDVAIIPECPICLQINMHKPDLVFFGEIHQSVNRS
YLDVERSDRLLLIGTTLSTFSAFRLLKHALQLQKPTLLINVGPSRADGIPGEKLDVPSGDIMRQVARNVIGN-------
>tr|A0A067NEW1|A0A067NEW1_PLEOS Uncharacterized protein OS=Pleurotus ostreatus PC15 GN=PLEOSDRAFT_1105491 PE=4 SV=1
----------------------------------------GNVTVLTGAGVSVDSGIRAYRGKDGRYMN-P--------NY--KPILYHQLVDRRRSFVG
YPDSQPNTTHFALAALQYK-SVISRLITQNVDGLHHKAIQSRILELHGTLHKVSCSS-GHVVDWKEDVVLVPDCPTCFSNCNHKPHLIFFGEIPQDVGRS
FTDVECGDRLLMMGTTLATFSAFRLVKHALEQHKPVMLLNVGPTRADDIPEEKVEIPTGTILRQVVAAVLGN-------
>tr|A0A067N6C6|A0A067N6C6_9HOMO Uncharacterized protein OS=Botryobasidium botryosum FD-172 SS1 GN=BOTBODRAFT_28251 PE=4 SV=1
----------------------------------------GNVLALTGAGVSVDSGIRAYRGNDGRYMN-P--------NY--HPIFYHELVDSRRSYFG
YPDAQPNPTHYAIAALQHA-NLVSRLITQNVDGLHPKALQSRILELHGMLRMVHCKN-GHVMSLRADVELVPECKDCAKNSILKPNVVFFGEIDQHLDRA
MNQVYNCRSVLVIGTTLATYSAYSLVKRAHELNKPIMVLNVGPTRADELSGEKFEWTSGEVLQEVCKTILGS-------
>tr|A0A0L6WJ38|A0A0L6WJ38_9AGAR NAD-dependent deacetylase OS=Termitomyces sp. J132 GN=J132_04619 PE=4 SV=1
----------------------------------------GNVAVLTGAGVSVDSGIRAYRGNDGRYMN-P--------NY--KPIFYHELMDERRSYLG
YPDAQPNTTHFALAALLHT-SVISHIVTQNVDGLHQKALQQTILELHGTLHRVHCKY-GHSVDWKEDVAIIPDCPSCLLNNIVRSTGRYVRVLP------
YQDIENSNKILIIGTTLATYSAYRLLKHALELKKPIMLLNVGPTRADGVAGVKIDMASGTIMRDVARIVLGS-------
>tr|V2X6T9|V2X6T9_MONRO Nad-dependent deacetylase OS=Moniliophthora roreri (strain MCA 2997) GN=Moror_14050 PE=4 SV=1
----------------------------------------GNVTVLTGAGVSVDSGIRAYRGKDGRYMN-P--------NY--KPIFYHELMDERRSYLG
YPDALPNTTHFALAALQYS-GIVPHLITQNVDGLHHKAIQDCILELHGTLHRVRCKH-GHVVDWLNDVAIVPECPTCLSNDVHKPDLVFFGELPSEVDRS
FRNIELADKLLLIGTTLATYSAFRLLKSALEQKKPVLMVNVGPSRADGIDGEKLDISSGTIMREVVRSVLGS-------
>tr|A0A0C2XIJ2|A0A0C2XIJ2_AMAMU Uncharacterized protein OS=Amanita muscaria Koide BX008 GN=M378DRAFT_1054375 PE=4 SV=1
----------------------------------------GNVTLITGAGVSVDSGIRAYRGQDGRYMN-P--------NY--KPILYHEFIGERRSYLG
YPDAQPNTTHYALAALQYT-NHIPRIITQNVDGLHHKAFNSRVLELHGSLHRVVCRS-GHVIDWKSDVAIVPDCPHCLSNVSVKPAFIFFGEIPEDTIEA
VQDVEASDRVLLIGTTLATYSSFRLVKHALELKKPVVMLNIGPTRADTLPGIKISLPAGLVMRDVAKAVIGS-------
>tr|A0A0D7BK20|A0A0D7BK20_9HOMO DHS-like NAD/FAD-binding domain-containing protein OS=Cylindrobasidium torrendii FP15055 ss-10 GN=CYLTODRAFT_179761 PE=4 SV=1
----------------------------------------GKTTLLSGAGVSVDSGIRAYRGHDGRYMN-P--------NY--KPIFYQELVDERRSFLG
YLNALPNTTHCALAALQYA-SVIPHIITQNVDGLHHKALERSILELHGSLHRVRCKN-GHLVDWQEDVAIVPDCPSCIDNNTHKPDLIFFGEIPTEVERS
FSDVERTDRLLVMGTTLATYSAFRILKHALDLGKQVLMVNVGPSRGDGVQGEKLDIASGAIMDAVTRTVLGS-------
>tr|A0A0D2LJX9|A0A0D2LJX9_9AGAR Uncharacterized protein OS=Hypholoma sublateritium FD-334 SS-4 GN=HYPSUDRAFT_130163 PE=4 SV=1
----------------------------------------GNVALLTGAGVSVDSGIRAYRGEDGRYMN-P--------NY--KPIFFHELMDPRRSYLG
YPDAQPNTSHFALAALQHT-SHLSHIITQNVDGLHHKAIQKSILELHGTLHHVQCSK-GHTVDWHQDVAVVPECPECMLNSAYKPRVIFFGEIPQPVIQS
YEVVENSERLLLMGTTLATYSAFRLLKHALELKKPVMLLNVGPTRADGMPSEKLDVPSGAVMRDVAKAVIGT-------
>tr|A8N8Z3|A8N8Z3_COPC7 Uncharacterized protein OS=Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003) GN=CC1G_00868 PE=4 SV=2
----------------------------------------GNVTVLTGAGVSVDSGIRAYRGPDGRYMN-P--------NY--KPIFYHELIDERRSYLG
YPDAQPNTTHFALASLSYS-GHVSQLITQNVDGLHHKALNRHILELHGTLHRVHCQR-GHAIDWHEDVAIVPECPHCFASSTHKPAVVFFGEIAKEVERS
FRDVEASDKLLLIGTTLATYSAFRLVKHALELEKPVVLLNLGPTRADNLPGDKIEWSSRSVLTEAAKTILAP-------
>tr|A0A0C3CLP8|A0A0C3CLP8_HEBCY Uncharacterized protein OS=Hebeloma cylindrosporum h7 GN=M413DRAFT_25129 PE=4 SV=1
----------------------------------------ANVTLLTGAGVSVDSGIRAYRGEDGRYMN-P--------NY--KPIFYHELMDSRRSYLG
YPDALPNTTHFSLAALQHT-SHISHIITQNVDGLHHKALQDNILELHGTLHRVHCSS-GHKVDWRQDVAIIPECPQCMLNPVHKPGVIFFGEIPSATERS
FREVEASDKFLIMGTTLATYSAFRLVKHALELKKPIMLLNVGPTRADGLPGEKIDVPSGAVMRQVAKEVIGT-------
>tr|A0A0H2R9R2|A0A0H2R9R2_9HOMO DHS-like NAD/FAD-binding domain-containing protein OS=Schizopora paradoxa GN=SCHPADRAFT_602978 PE=4 SV=1
----------------------------------------GNVVALTGAGVNVGLDTHGRRGSDGLYTI-P--------NF--KSMLYRDLIDERQSYLS
YPDAQPNATHLALTALQHS-GHISKLITQNVDGLHLKAAVDNIIQLHGTLHSVRCAF-GHSVDWAA-MMLVPKCPTCLERSIQMTDVVHFGDIPETIKQS
LKAIEDAERLLIVGASPMTPFARGLLNEALSLRKPVLMVDVGPENADSQDAEKIEIPSRSLLPSVVEQLLST-------
>tr|A0A0C3ALD2|A0A0C3ALD2_9HOMO Uncharacterized protein OS=Serendipita vermifera MAFF 305830 GN=M408DRAFT_331167 PE=4 SV=1
----------------------------------------GPVTVLTGAGVSVDSGIRAYRGKDGRYMN-P--------NY--QPILYQELVAPRRSYLG
YPDAKPNASHYGLSLLQRH-GKIGTIITQNVDGLHLRAGKKAVVELHGTLFVVRCSH-GHEIDWKADIELVPACPTCRVDRTLKPDVVFFGEVPEEKNRS
LAEVASSERLLVVGTTLATYSAYRLFQLAHNNHKPVVILNIGPTRADTVPSTKLEVPCGELLREVAERMCAN-------
>tr|G4THG9|G4THG9_PIRID Related to NAD-dependent deacetylase sirtuin type 4 OS=Piriformospora indica (strain DSM 11827) GN=PIIN_04697 PE=4 SV=1
----------------------------------------GPATVLTGAGVSVDSGIRAYRGKDGRYMN-P--------NY--QPILYQQLMAPRRSYLG
YPEAKPNIAHYSLTALEHH-GFVNRLITQNVDGLHARSGKEKLLELHGTLFVVKCRQ-GHELDWKADIELIPPCPTCLKETTIKPDVVFFGEIPEYKQQS
LQEILDADRFLVVATTMATYSAYRLLQLAHQNKKPIVIVNIGPTRGDHLQ-PQIELPCGDVLKECALRLSR--------
>tr|J9VPM7|J9VPM7_CRYNH Uncharacterized protein OS=Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) GN
----------------------------------------GKTVILTGAGVSVDSGIRAYRGKEGSYSN-P--------NY--KPILFHELVEDRRSFLG
YPDAQPNPTHIYIAALLYL-GLAPNLITQNVDNLHPKAYKPPILELHGTLAKVHCMKH--EQSWDEDVDLVPSCRICEAPTMVKPNVVFFGEIPPVVDES
FSLINSASSLLILGTSLATYSAFRLVKLALDQKKPVLMISTGPSRADGLPGEKMDRVAGDVLGVYLDSVVKG-------
>tr|A0A0F7SIT5|A0A0F7SIT5_PHARH Sirtuin 4 and related class II sirtuins (SIR2 family) OS=Phaffia rhodozyma PE=4 SV=1
----------------------------------------GRTLVITGAGVSVDSGIRAYRGKEGHYTN-P--------NF--RPVYYGELVDPRRGFLG
WPDSQPNPIHYGIAAMMWM-GLSRQLITQNVDGLHNKASDQRILALHGTLHLVHCKQK-HTVSWKMDVDLVPSCQDCG--DIVKPNVVFFGEIAEDVERA
SQAITDSSQILVLGTSLATYSAFRLIKQAKEENKPILMVSTGPSRADG-DGDKIEMEAGPVLKLALKELSVG-------
>tr|G7E2D5|G7E2D5_MIXOS Uncharacterized protein OS=Mixia osmundae (strain CBS 9802 / IAM 14324 / JCM 22182 / KY 12970) GN=Mo03669 PE=4 SV=1
----------------------------------------GKTLILTGAGVSVDSGIRAYRGDNGSYTN-K--------TY--RPIFYSEFMAPRRSYLG
YPLAQPNPSHYAIAALQYM-GLAPYIITQNVDRLHHRASISTILELHGTLKHVHCTNCKHEISWAADVDLLPKCISCG-SGPMKASVCFFGEVPAKTERS
HSLVENASNLLVVGSALATYSAFRLVKQAHEAGKQVMMINIGQSRADSFVETRIERPSTEVLLGAAQSLAES-------
>tr|E3KJ55|E3KJ55_PUCGT Putative uncharacterized protein OS=Puccinia graminis f. sp. tritici (strain CRL 75-36-700-3 / race SCCL) GN=PGTG_10050 PE=4 SV
----------------------------------------GNVLAISGAGMSVDSGIRAYRGAKGSYIN-K--------SY--RPIFFHEFLESRRSYLG
YPVAEPNVGHYAVAALMKM-GYIRHLITQNVDRLHHKAIHPNILELHGTLKHVNCLSC----DWKNDADVVPNCEKCT-VGLLKPAVTFFGELSKEAELA
NRRVSEATNLLLLGTSLTTYSAFRLVKELKEKGSQIGMINIGTTRADELID-TGGLGCSQVLKEVGLQLAAR-------
>tr|K9HJV4|K9HJV4_AGABB Uncharacterized protein OS=Agaricus bisporus var. bisporus (strain H97 / ATCC MYA-4626 / FGSC 10389) GN=AGABI2DRAFT_185963 PE=4
----------------------------------------GNVTVLTGAGVSVDSGIRAYRGHDGRYMN-P--------NY--KPILYHELMDERRSYFG
YPDALPNTTHHALAALQHA-GIVSHLITQNVDRLHHKALTPSILELHGTLSNVCCNH-GHVIDWVTDVDLIPECSQCLKNTIIKPQVIFFGEIPLSIEAS
YNAIDSSDRLLIVGTTLATYSAFRLLKRALETHKDVAVLNLGPTRADGILAQKIEHHSGLVLRDAAKSVWFP-------
>tr|A0A0C3GIB6|A0A0C3GIB6_9HOMO Uncharacterized protein OS=Piloderma croceum F 1598 GN=PILCRDRAFT_812116 PE=4 SV=1
----------------------------------------GNVAVLTGAGVSVDSGIRAYRGKNGRYLN-P--------NY--KPILYHELMDERRSYLG
FPDALPNTTHFALVALQYT-SVVSQLITQNVDGLHLKALQDRILELHGTLHKVRCKY-GHVVDWKRDVALVPDCPSCLMNSVHKPEVIFFGEIPRDVDRS
LTTIEKCDRLFIIGTTLATYSAFRLVKHALELNKPVLLLNVGPSRADGHPGEKIELASGVIMREVVKAVIGI-------
>tr|A0A0D0DUS5|A0A0D0DUS5_9HOMO Unplaced genomic scaffold scaffold_79, whole genome shotgun sequence OS=Paxillus rubicundulus Ve08.2h10 GN=PAXRUDRAFT_824083 PE
----------------------------------------GNVALLTGAGVSVDSGIRAYRGKDGRYMN-P--------NY--KPIFYHELIADRRSYLG
YPDTQPNTTHCALAALQHT-GHISRLVTQNVDGLHRKAIEERILELHGTLHRVHCQF-GHVTSWKADVELVPECPECMLNSNQKPEVIFFGEIPKAIERS
FHDVEQSDRLFLVGTTLATFSAYRLIKHALKLKKPVLLLNMGATRADDLPGEKIEISTSHVMRDTVRAVLGT-------
>tr|A0A0D0BEZ5|A0A0D0BEZ5_9HOMO Unplaced genomic scaffold CY34scaffold_8, whole genome shotgun sequence OS=Suillus luteus UH-Slu-Lm8-n1 GN=CY34DRAFT_706658 PE=
----------------------------------------GKVTLITGAGVSVASGIRAYRGKDGRYMN-P--------NY--QPIFYHELTDQRRSYLG
YPDALPNTSHYAIAALQYA-SYLPRLVTQNVDGLHHKAIQKQVLELHGTLHRVHCMR-GHTVPWREDVELVPGCPQCTLNSFHKPEVIFFGEIPSRINRS
FHDVEESERVFVLGTTLATYSAFRLVKRALELRKPVMLLNVGPTRADGLPGEKLEISSSLVLRDVVRAIL---------
>tr|F8Q3Y4|F8Q3Y4_SERL3 Putative uncharacterized protein OS=Serpula lacrymans var. lacrymans (strain S7.3) GN=SERLA73DRAFT_58639 PE=4 SV=1
----------------------------------------GNVTVLTGAGVSVDSGIRAYRGKDGRYMN-P--------NY--NKFICHGLYHFRRSYIG
YPASRPNTTHFALAALQYT-SHITKLITQNVDGLHQKSIPNNILELHGTLHRVHCKF-GHITTWREDVALVPNCPQCTLNSIQKPEVIFFGEIPKAVERS
YSDVEQCDRLFLVGTTLATYSAFRLLKHALDLRKPVMILNVGPTRADALPGEKIELASGLIIRDVVRAVM---------
>tr|A0A0C3JNG8|A0A0C3JNG8_PISTI Uncharacterized protein OS=Pisolithus tinctorius Marx 270 GN=M404DRAFT_128450 PE=4 SV=1
----------------------------------------GSVTLLTGAGVSVDSGIRAYRGKDGRYMN-P--------NY--Q--YYHELVDRRRSYLG
YPDALPNTTHCALAALQYT-SHISRLITQNVDGLHRKAINERMLELHGSLHRVHCNH-GHVVDWKDDVELIPECPQCVLNTNQKPTVIFFGEIPTIVNRS
FHDVERSDRLFVVGTTLATFSAFRLVQHAVKLGKPVLLLNMGATRGDGLPGEKIEIPASYVIRDVARTILGT-------
>tr|A0A0C3ALZ9|A0A0C3ALZ9_9HOMO Uncharacterized protein OS=Scleroderma citrinum Foug A GN=SCLCIDRAFT_111445 PE=4 SV=1
----------------------------------------GNVVLLTGAGVSVDSGIRAYRGKDGRYMN-P--------NY--RPIFYHELVEERRSYLG
YPDAQPNTTHCALAALQYT-SHISRLVTQNVDGLHKKAISERILELHGTLHRVHCKY-GHVTDWKDDVELVPECPQCRLSTNQKPAVIFFGEIPVAIDRS
FHDIEQSDRLLLVGTTLATFSAFRLVQHAIKLGKPVLLLNVGPTRVDNLRAEKIEIPTSHVMRDVVKAVLGM-------
>tr|A0A067Q5T2|A0A067Q5T2_9HOMO Uncharacterized protein OS=Jaapia argillacea MUCL 33604 GN=JAAARDRAFT_30963 PE=4 SV=1
----------------------------------------GNAALITGAGVSVDSGIRAYRGKDGRYMN-P--------NY--KPIFYHELIDERRSYLG
YPDALPNTTHFALAALQYS-SSITQLITQNVDGLHHKAFSERILELHGTLHRVHCKF-GHTVDWKADVALVPECPSCMLNSIHKPEVIFFGEIPQDVERS
FLDVAKCDRLFIVGTTLATYSAFRLLKHALELKKPVLYLNLGPTRADGITEEKIELSSSLLLRDVVRALLGT-------
>tr|J4G7P5|J4G7P5_9APHY Uncharacterized protein OS=Fibroporia radiculosa GN=FIBRA_04635 PE=4 SV=1
----------------------------------------GNVAVVTGAGVSVDSGIRAYRGAKGRYLN-P--------NY--KPIFYHELMDARRSYLG
YPDALPNTTHYALAALQYA-SVVPKLITQNVDGLHHKALERGILELHGRLRAVRCVH-GHLTDWKADVVLVPDCPECHANNIHKPEVIFFGEITKDVDRS
FHDIESCDRLFLVGTTLATFSAFRLLKHALDWRKPVLLLNVGPSRADALPGEKIEVASGAVMRDVVRTVLGT-------
>tr|A0A0C3S0U9|A0A0C3S0U9_PHLGI Uncharacterized protein OS=Phlebiopsis gigantea 11061_1 CR5-6 GN=PHLGIDRAFT_111785 PE=4 SV=1
----------------------------------------GNVTTITGAGVSVDSGIRAYRGSKGRYLN-P--------NY--KS--YQELVDPRRSYLG
YKEARPNTTHYALAALQHT-NVIPKLITQNVDGLHHKSLKERILELHGSLHKVQCSH-GHIVDWKVDVALVPECPDCLLNSILKPELIFFGEIPPEVDRS
IADIEECDRLFLVGTTLATYSAFRLLKHALELKKPVLLLNVGPTRADPLPGEKIELASGLVMRDVVRAVL---------
>tr|A0A0C3QWJ8|A0A0C3QWJ8_9HOMO Uncharacterized protein OS=Tulasnella calospora MUT 4182 GN=M407DRAFT_151698 PE=4 SV=1
----------------------------------------KNALVMTGAGVSVDSGIQAYRGSDGRYAN-P--------NF--KPIFYQELMDSRGGYLG
WRRSDPNPTHFALAALQHL-DVAPRLITQNVDGLHQRASDSRTLELHGTLNTVRCLR-GHKMPWKADVDLVPECAECAAGSILKLEVIFFGEIPNEVERS
FRMVDESDRLLLVGTTLATFSAFRLVKYALEQNKPVVLLNLGPARTDSIPQEKIELPSREVLLEACRLLAGS-------
>tr|K5ULU9|K5ULU9_PHACS Uncharacterized protein OS=Phanerochaete carnosa (strain HHB-10118-sp) GN=PHACADRAFT_213556 PE=4 SV=1
----------------------------------------GNVATVTGAGVSVDSGIRAYRGSKGRYLN-P--------NY--KPIFYQELVDARRSYLG
YKDALPNTTHYALAALQYT-NIIPKLITQNVDGLHHKALNQHILELHGSLHKVHCSH-GHIVDWKADVFLVPECPDCLLNSILKPELIFFGEIKREVDRS
QLDVENCSRLFLVGTTLATYSAFRLVKHALELKKPVLLLNVGPTRADPLSGEKIELPSGTVLRDAVRTVLGS-------
>tr|M2QQA2|M2QQA2_CERS8 Uncharacterized protein OS=Ceriporiopsis subvermispora (strain B) GN=CERSUDRAFT_112916 PE=4 SV=1
----------------------------------------GNVALITGAGVSVDSGIRAYRGAKGRYLN-P--------NY--RPIFYHELMDERRSYLG
YPDALPNTTHYALAALQHT-GVIPSLVTQNVDGLHHKALQERILQLHGTLHKVNCKF-GHVTDWKADVVLVPDCPSCLENSVHKPDVIFFGEISQEIDRS
FRDVEECDRLFLLGTTLATFSAFRLLRHALELKKPVLLLNIGPTRADGIPGEKLEIPSNLVMRDAVKAVLGP-------
>tr|S7Q9Q3|S7Q9Q3_GLOTA DHS-like NAD/FAD-binding domain-containing protein OS=Gloeophyllum trabeum (strain ATCC 11539 / FP-39264 / Madison 617) GN=GLOT
----------------------------------------GNATVITGAGVSVDSGIRAYRGKDGRYTN-P--------NY--KPIFYHELIDERRSYLG
YPDALPNTTHYALAALQYA-GLVPRLITQNVDGLHHKALRERILELHGTLHKVHCNH-GHTVDWKADVVLVPHCPSCMLNSVLKPEVIFFGEIRQQVERS
FEDVEKGDRLFVVGTTLATYSAFRLLKHALQLKKPVLMLNVGPTRADSIAEDKIDLPTSAVLREVVKALVGV-------
>tr|R7SNC6|R7SNC6_DICSQ DHS-like NAD/FAD-binding domain-containing protein OS=Dichomitus squalens (strain LYAD-421) GN=DICSQDRAFT_183322 PE=4 SV=1
----------------------------------------GNTAVITGAGVSVDSGIRAYRGEHGSYLN-P--------NY--KPIFYHELMEARRSYLG
YPDAQANPTHYALAALQYS-SVTPHIITQNVDGLHHKAINQGILELHGTLHRVRCSH-GHAIDWKADVVLLPDCPDCLKNDLLKPEVIFFGEIPAPVDRS
FEIVDSSDRLFVVGTTLATFSAFRLVKYAIEHHKPVLLLNIGPTRADQLVGETIEIPAGSVMREVVKGVLGS-------
>tr|A0A060SAF5|A0A060SAF5_PYCCI Uncharacterized protein OS=Pycnoporus cinnabarinus GN=BN946_scf184746.g34 PE=4 SV=1
----------------------------------------GNAAVITGAGVSVDSGIRAYRGHKGSYLN-P--------NY--KPIFYHELMEPRRSYLG
YPDAQPNPTHFALAALQHS-SVTPHIITQNVDGLHHKAIKEGILELHGTLHRVKCSH-GHEMEWKADVVLVPECPSCLLNSMIKPEVIFFGEIPSEVDRS
FDIVDQHDRLFVIGTTLATFSAFRLVKHAIQQHKPVLVLNVGPTRARELAVETIEIPAGAVLRDVVKQVLGS-------
>tr|A0A0H2RGB1|A0A0H2RGB1_9HOMO DHS-like NAD/FAD-binding domain-containing protein OS=Schizopora paradoxa GN=SCHPADRAFT_835150 PE=4 SV=1
----------------------------------------GNVAVLTGAGVSVDSGIRAYRGDDGRYMN-P--------NY--KPILYHELMDERRSYLG
YPDAQPNTTHFALAALQYL-GIVSRLITQNVDGLHHKAIERKMLEIHGTLHRVHCTF-GHVVDWAEDVVLIPDCPECTLNSIQKPNLIFFGEISAEVERS
YRDVEFADRLFIVGTTLATFSAFRLLKHAIELRKPVLMLNVGPTRADTIPGEKIEVQSGAVLRDIVKSLAGF-------
>tr|E6ZYY6|E6ZYY6_SPORE Related to NAD-dependent deacetylase sirtuin type 4 OS=Sporisorium reilianum (strain SRZ2) GN=sr13151 PE=4 SV=1
----------------------------------------GKALIMTGAGVSVDSGISAYRGDKGHYTN-R--------EY--RPIFYHEFIDERRSYLG
FPVAQPNRTHYSVAAIQRL-GYVPEFITQNVDNLHHAATASTILELHGTLKHVVCVSSGFRGSWAQDVELYPACPNCG-GV-LKPAVIFFGEVPDKLDHS
YRMVDGAEAMLLVGTSLATYSAFRLVKQAVEQKKRVLILNKGPTRADPQVENKIELGSSEVLSRVAGLLSN--------
>tr|R9APU0|R9APU0_WALI9 NAD-dependent protein deacetylase SIR4 OS=Wallemia ichthyophaga (strain EXF-994 / CBS 113033) GN=J056_002305 PE=4 SV=1
----------------------------------------GKTAILSGAGASVESGIRSYRGKEGHYEH-K--------KY--RPIFYHEFIEDRRSFFG
YINAKPNRVHYSVAALQYM-NLVDKLVTQNVDRLHHRATDSRILELHGTLNFAVVPSH---KLWAEDVELVPPPDGLEGSAFYKPDVVFFGELSPHQEES
IKAIEDADRVLVVGSSLATYSAFRLIKQAIESKKQVLMLNVGPSRADDYDITKIELPAADVLQGAVKLLASK-------
>tr|V5EXU5|V5EXU5_PSEBG Uncharacterized protein OS=Pseudozyma brasiliensis (strain GHG001) GN=PSEUBRA_SCAF16g05266 PE=4 SV=1
----------------------------------------GKALIMTGAGVSVDSGIAPYRGENGHYTH-T--------TY--RPIWHSEFVDKRRSYLG
FPVAKPNITHHAIAAIQRL-GYVPEYITQNVDNLHHAATQASILELHGSLARVICVSSGFEGSWAEDVDLYPSCPNCG-GV-LKPAVIFFGEVPNQLDHS
FQMVDNASAMLLVGTSLATYSAYRLVKQAVEAKKPVMILNKGPTRADPIVENKIELGSSEVLQGVARNLSN--------
>tr|A0A077R290|A0A077R290_9BASI Related to NAD-dependent deacetylase sirtuin type 4 OS=Melanopsichium pennsylvanicum 4 PE=4 SV=1
----------------------------------------GKALIMTGAGVSVDSGIAPYRGENGHYTH-K--------TY--RPIFFHEFIDPRRSYLG
FPVAKPNRTHYSIAAIQRL-GYVPEFITQNVDNLHHAATASTILELHGTLKHVVCVSSGFRGSWAQDVELYPACPNCG-GV-LKPAVIFFGEVPDKLDHS
YQMVDNANAMLLVGTSLATYSAYRLVKQAVEQNKPILILNRGPTRADPLVQNKIELGSSQVLSLVANLLSN--------
>tr|A0A061HFT0|A0A061HFT0_9BASI Uncharacterized protein OS=Anthracocystis flocculosa PF-1 GN=PFL1_03226 PE=4 SV=1
----------------------------------------GKGLIMTGAGASVDSGIAPYRGENGHYTH-K--------TY--RPIFYHEFIDERRSYLG
FPTAQPNKTHYSIAAIQRL-GYVPEFITQNVDNLHHAATASTILELHGTLKNVVCVQSGFRGSWAQDVDLYPSCPSCG-GV-LKPAVIFFGEVPDVLDHS
YQLVRDASAFLLVGTSLATYSAFRLVKQAVEDGKPVLILNKGPTRADPIVDNKIELGSSEVLNATARLLSS--------
>tr|A0A081CB56|A0A081CB56_CANAR DHS-like NAD/FAD-binding domain-containing protein OS=Candida antarctica GN=PAN0_004c2111 PE=4 SV=1
----------------------------------------GKALIMTGAGVSVDSGIAPYRGEKGHYTH-K--------TY--RPIFYHEFTDPRRSYLG
FPVAQPNKTHYSIAAIQRL-GYVPEFITQNVDNLHHAATASTILELHGTLKHVVCVSSGFRGSWAQDVELYPACPNCG-GV-LKPSVIFFGEVPDRLDHS
YAMVDDARALLLVGTSLATYSAFRLVKQAVEQAKPVMILNRGPTRADGIVESKIELGSSEVLSRVAALLSN--------
>tr|R9NX00|R9NX00_PSEHS Histone deacetylase OS=Pseudozyma hubeiensis (strain SY62) GN=PHSY_000598 PE=4 SV=1
----------------------------------------GKALIMTGAGVSVDSGIAPYRGENGRYLN-Q--------TF--RPIFYHEFTDTRRSYLG
FPRAEPNVSHYSIAALQRL-GYLQGLITQNVDNLHSAATASTILELHGTLKHVVCVGEGFMGSWAEDVELYPSCPGCG-SALVKPTVCFFGEVPDKIDNS
FHMVDQSSALLLIGTSLATYSAFRLVKQAVEQKKPVMILNKGPTRADGIVPDKIELGSSEVLSRVAALLSN--------
>tr|A0A066VFP6|A0A066VFP6_9BASI DHS-like NAD/FAD-binding domain-containing protein OS=Tilletiaria anomala UBC 951 GN=K437DRAFT_259739 PE=4 SV=1
----------------------------------------RKNLIMTGAGVSVDSGIAPYRGENGHYTH-K--------TY--RPIFFHEFTALRRSYLG
FPHALPNKTHYSIAALQRL-GHVPEFITQNVDSLHHAATAASILELHGTLAYVVCVSRGFRGSWADDVQLYPPCPSCG-GV-LKPAVVFFGEVPDELDRS
HALVASSDSFMLVGSSLATYSAFRLVKQAVEERKRVMIVNIGPTRADPIVPDKIELPSSDVLGNAAKLLAG--------
>tr|A0A0P1BJJ9|A0A0P1BJJ9_9BASI Sirtuin 4 and related class II sirtuins (SIR2 family) OS=Ceraceosorus bombacis PE=4 SV=1
---------------------------------------------MTGAGVSVDSGIAPYRGEGGHYEH-K--------TY--RPIFFHEFVDSRRSFLG
YPVARPNKTHYAVAALQRL-GAFADYITQNVDSLHHMATASSILELHGTLQHVLCVSSGFRGSWDEDVELYPACPSCG-GV-LKPGVVFFGEVPDALDRS
FELVRRASQMLIVGSSTATYSAYRLAKTMHEAGGSVMILNKGPSRADPLASDKIELGSSEVLQLVAQRLAGT-------
>tr|I4YGP3|I4YGP3_WALMC DHS-like NAD/FAD-binding domain-containing protein OS=Wallemia mellicola (strain ATCC MYA-4683 / CBS 633.66) GN=WALSEDRAFT_5944
----------------------------------------GKTAIVSGAGASVESGIRAYRGNQGHYEH-K--------KY--RPIFYHEFMEDRRSFFG
YIHALPNRVHYNVAALQYM-NLVDKLVTQNVDRLHHRASDDRILELHGTLNFAVVPNY---KLWLEDVELIPNPNGLEDRAFYKPDVVFFGELDVRQEES
VKAIHDADRILVIGSSLATYSAFRLIKQAIEAKKQVLMINIGPTRADDYDITKIELPAADVLQGAVKLLASK-------
>tr|A0A0D1E6Y0|A0A0D1E6Y0_USTMA Chromosome 4, whole genome shotgun sequence OS=Ustilago maydis (strain 521 / FGSC 9021) GN=UMAG_05239 PE=4 SV=1
----------------------------------------GKALIMTGAGISVDSGIAPYRGENGHYTH-K--------HY--RPIFYHEFVDARRSFLG
FPVAQANKGHYSIAAIQRL-GYVPEYITQNVDNLHHAATASTILELHGTLKHVVCVSSSFRGSWAQDVELYPACPNCG-GV-LKPAVIFFGEVPDKLDHS
YEMVENANAMLLIGTSLATYSAFRLVKQAVEQNKPVMVLNRGPTRADGILPAKIELGSSEVLSKVAHLLSN--------
>tr|A0A0J0XC97|A0A0J0XC97_9TREE DHS-like NAD/FAD-binding domain-containing protein OS=Trichosporon oleaginosus GN=CC85DRAFT_289273 PE=4 SV=1
----------------------------------------GRTLAITGAGVSVDSGIRAYRGEEGRYLN-P--------NY--SPIFYSELIEDRRSFLG
YPDAKPNPTHIYIAALQAL-GLAPGLITQNVDNLHRKALVTPILELHGTLARVHCLRHGHEQSWAADVELVPACALCVAKSIVKPNVIFFGELPPAVDKS
FELVEAASSLLIMGTTLATYSAFRLIKAAREQGKPVFMISLGPSRADDLDGQKMERVAGPVLRAFLDDYLTT-------
>tr|A0A066VHM1|A0A066VHM1_9HOMO Uncharacterized protein (Fragment) OS=Rhizoctonia solani AG-8 WAC10335 GN=RSAG8_09765 PE=4 SV=1
----------------------------------------RNTLVVTGAGVSVESGIRAYRGKTGRYMN-P--------NY--KPILYHELVDPRRSYLG
YPDAQPNPTHFALAALQWA-DFVPRLITQNVDGLHHKAIPGHILELHGTLHTVHCRR-NHEVDWKDDVDILPICAACLADDVMKPAVIFFGEIPQEVQQS
FSDVEASDRVLFIGTTLATFSAFRLLKHAIELNKPVMLLNLGPTRAHSVPEEIIEAASRDVLRGAARALTSD-------
>tr|M5G6P2|M5G6P2_DACSP DHS-like NAD/FAD-binding domain-containing protein OS=Dacryopinax sp. (strain DJM 731) GN=DACRYDRAFT_77675 PE=4 SV=1
----------------------------------------GNAVVLTGAGVSVDSGIRAYRGHDGRYLN-P--------NY--KPIFYQELVDPRRSYLG
YPDALPNPIHYSLAALQHT-GHCRSLITQNVDGLHKKASRRRILELHGTLFIVHCKH-GHTWDWQPDVEVIPPCERCAAETVIKPNVTFFGEIHEPLDQS
YRLVEEASRMLIVGTTMATYSAFRLIRHALGLDKPVLLLNVGPTRADSLPAEKIELPAGDVIRNVAQALCAT-------
>tr|A0A0B7FJD2|A0A0B7FJD2_THACB NAD-dependent protein deacetylase SIR4 OS=Batrachochytrium dendrobatidis (Strain JAM81 / FGSC 10211) GN=BATDEDRAFT_20316 PE=3 S
----------------------------------------GNALIVTGAGVSVESGIRAYRGTSGRYMN-P--------NY--KPILYHELVDTRRSYLG
YPDAQPNPTHFALAALQWT-GLVPRLITQNVDGLHQKAIPGHILELHGTLHSVHCKR-NHTTNWKDDVDILPVCKTCLADDVMKPAVIFFGEIPQEVQRS
FSDVEASDRVLFIGTTLATYSAFRLLKHAVELNKPAMLLNLGPTRAHGVPEEIIEAASSDVLRAATRALTSN-------
>tr|J6FC44|J6FC44_TRIAS Uncharacterized protein OS=Trichosporon asahii var. asahii (strain ATCC 90039 / CBS 2479 / JCM 2466 / KCTC 7840 / NCYC 2677 / U
----------------------------------------EGTLIVTGAGVSVDSGIRAYRGKEGAYMN-P--------NY--HFNCSEKLTPAERSFLG
YPAAQPNPLHIYLASLQAL-GLSHGLLTQNVDNLHRKALASRILELHGTLAKVHCLQN--EGTWDQDVELVPPCSQCAAEGVVKPNVIFFGELPSYVEES
FQLIDAASRLLVLGSTLATYSAFRLIKRAYEAGKPVLLISQGPSRADELD-FRMDRVAGPVMRAALENLLSG-------
>tr|A0A0N4WPV5|A0A0N4WPV5_HAEPC Uncharacterized protein OS=Haemonchus placei PE=3 SV=1
----------------------------------------DKLLVLTGAGVSTESGIPDYRSEKIGLFR-T--------NY--RPVTIQEFLASRRNFLA
WPSAQCNEAHRAIASWERS-KKFVWLITQNVDGLHAKAGSHMLTELHGCSLRVKCLGCGEITNWMKDTILLPECQKCG--GMLKTDVVFFGDVSREDDTC
YEKVEECTGVLVLGSSLYVMSGFRFPYHASLMGKPVLIVNIGPTRADEFAEMRISAPVSELEQCTGVLVLGS-------
>tr|A0A0M3K1M7|A0A0M3K1M7_ANISI Uncharacterized protein OS=Anisakis simplex PE=4 SV=1
----------------------------------------NRFLVLTGAGISTESGIPDYRSEKVGQYR-S--------NH--RPMDHSTFMKSRRNAIA
WPKSEPNATHYQIAKWEMS-DRFSWLITQNVDGLHRKAGSKLLTELHGCSHRVRCMNCNQVYPWYVDIAILPYCPSCGPGSILKTDVVFFGDVAGKIDFC
YQKLEESDGILVLGSSLAVMSGYRFVHKASLRGMPILIVNIGPTRGDHLATVKLTARCGDIIQSI--------------
>tr|E3MJE7|E3MJE7_CAERE Putative uncharacterized protein OS=Caenorhabditis remanei GN=CRE_19119 PE=3 SV=1
----------------------------------------DKLLVITGAGISTESGIPDYRSKDVGLYR-I--------SH--KPIYHQDYMRSRRNFLA
WPQAAPNINHYSLAKWEAS-ERFLWLITQNVDGLHHKAGSKMVTELHGNALGVQCTNCDYKESFKDDIILIPECPCCG--GLMKTSVTFFGDVPIDKNFC
YEKVAECDGILSLGSSLAVLSGFRFIHHANLQKKPVFIVNIGPTRADHMATMKLDYKISDVLKEM--------------
>tr|H2VXC1|H2VXC1_CAEJA Uncharacterized protein OS=Caenorhabditis japonica GN=WBGene00126196 PE=3 SV=1
----------------------------------------EKLLVLTGAGMSTESGIPDYRSKDVGLYR-I--------AH--KPIYHQEFMKSRRNYLA
WPSAAPNINHYSLAKWEAS-DRFLWLITQNVDGLHLKAGSKMVTELHGSALQVICTNCEYREMFREDVSLIPECPDCG--GIMKTDVTFFGDVSMSKNSC
YEKVDECDGILALGSSLAVLSGYRFVYHAHLQNKPVFIVNIGPTRADHMATMKLDVKLSDVLNKI--------------
>sp|Q20480|SIR41_CAEEL NAD-dependent protein deacylase sir-2.2 OS=Caenorhabditis elegans GN=sir-2.2 PE=3 SV=1
----------------------------------------DKLLVISGAGISTESGIPDYRSKDVGLYR-I--------AH--KPIYFQDYMRSRRNFLA
WPQAAPNINHYALSKWEAS-DRFQWLITQNVDGLHLKAGSKMVTELHGSALQVKCTTCDYIESFKEDIILIPECPSCG--GLMKTDVTFFGEVNMDKNFC
YEKVNECDGILSLGTSLAVLSGFRFIHHANMKKKPIFIVNIGPTRADHMATMKLDYKISDVLKEM--------------
>sp|Q20481|SIR42_CAEEL NAD-dependent protein deacylase sir-2.3 OS=Caenorhabditis elegans GN=sir-2.3 PE=3 SV=1
----------------------------------------DKLLIITGAGISTESGIPDYRSKDVGLYK-T--------AL--EPIYFQDFMKSRRSYLN
WPQALPNFNHYALSKWEAA-NKFHWLITQNVDGLHLKAGSKMITELHGNALQVKCTSCEYIETFKEDTALIPECLNCG--GLMKTDVTLFGELNTDKKVC
GKKVNECNGVLTLGTSLEVLSGYQIVNHAHMQNKPIFIVNIGPTRADQMATMKLDYRISDVLKEM--------------
>tr|A0A0B2VHE9|A0A0B2VHE9_TOXCA NAD-dependent protein deacetylase sirtuin-4 OS=Toxocara canis GN=SIRT4 PE=4 SV=1
----------------------------------------DRLIVLTGAGISTESGIPDYRSEKVGQYR-T--------NY--RPVDHTDFMSSRRNLVQ
YPRSKPNIVHKTIADWEKS-SKFTWLITQNVDGLHTEAGSRKVTELHGCGRRVRCMKCNTLYPWLEGEHLLPHCPKCGPGSILKTDVIFFGDLRGEDSTS
YEKLEQSNGMLVLGSSLQVMTGYNIVRAAFVQSMPIVIVNIGPTGADDLATMKIAAKCSDVVKEVQL------------
>tr|F1L8U6|F1L8U6_ASCSU NAD-dependent ADP-ribosyltransferase sirtuin-4 OS=Ascaris suum GN=ASU_09644 PE=2 SV=1
----------------------------------------SRFTVLTGAGISTESGIPDYRSEKVGQYR-S--------KH--RPIDYQTFMKSRRNAIA
WPRSEPNTTHHAIASWEQS-DKFNWLITQNIDGLHTKAGSRMLTELHGCGHRVRCMNCRAVFPWYVDIPILPCCPHCGPGSILKTDVVFFGDVPREDDKC
YEKLEESDALLVLGSSLMVMSGFRFVQRAHVRRMPILIVNIGPTRADHLATVKVSAKCTDIIKYI--------------
>tr|A0A0B2UZ86|A0A0B2UZ86_TOXCA NAD-dependent protein deacetylase sirtuin-4 OS=Toxocara canis GN=SIRT4 PE=3 SV=1
----------------------------------------GRFVVLTGAGISTESGIPDYRSEKVGQYR-S--------KH--RPIDYQTFMKSRRNAIA
WTQSKPNATHYAIANWEKS-DRFKWLITQNVDGLHRMAGSQMLTELHGSGHRVRCMNCKEIFPWYVDIYILPYCPHCGPDSILKTDVVFFGDVPKDTDKC
YEKLEDCDGILVLGSSLMVMSGYRFVYQASLRSMPIFIVNIGSTRADHLATMKIAARCTDIVKNI--------------
>tr|A8X440|A8X440_CAEBR Protein CBR-SIR-2.2 OS=Caenorhabditis briggsae GN=sir-2.2 PE=3 SV=2
----------------------------------------NKLVVLTGAGISTEPGIPDYRSKDVGLYR-I--------AH--KPIYHQDYMRSRRNFLA
WPQAAPNINHYSLAKWEAS-DRFHWLITQNVDGLHHKAGSNMVTELHGNALHVHCTTCDYTESFKDDIILIPECPCCG--GLMKTSVTFFGDVKMDKNFC
YEKVDQADGILALGTSLAVLSGFRFIHHAHLQKKSIFIVNIGPTRADHMATLKLDYKISDVLSEL--------------
>tr|A0A0N5APN8|A0A0N5APN8_9BILA Uncharacterized protein OS=Syphacia muris PE=4 SV=1
----------------------------------------DRFVVLTGAGVSTESGIPDYRSEKVGQYR-S--------KH--RPINHNVFMASRRNFIG
WSKCEPNINHYEMAKWESS-SKFVWLITQNVDKLHTKAGSKMLTELHGCGHRVRCMQCQRIYPWTVDIELLPFCPHCGPKSILKTDVVFFGDVPRKTDFC
YEKINECDGLLVVGSSLTVMSGYRFAYHASQRKIPIFIVNIGLTRADNLATVKLSARCSDVIPYISML-----------
>tr|A0A0N4U6G4|A0A0N4U6G4_DRAME Uncharacterized protein OS=Dracunculus medinensis PE=4 SV=1
----------------------------------------NKLIVMTGAGISTESGIPDYRSEKVGQYR-S--------NH--RPIEHRDFMQHRRNFVA
WPESKPNLIHETIASWEKT-DKFVWLITQNVDGLHTKAGSKMLSELHGCNRQVKCMNCSELYPWLVDIEIPPHCPKCGPGSILKTDVVFFGDVSSDVELC
YDKVFESDGMLILGSSLTVMSGYRFVLQAHSLQIPIIIVNIGPTRADDIATIKLSAKCSDIIKNIQILS----------
>tr|A0A0R3RFZ9|A0A0R3RFZ9_9BILA Uncharacterized protein OS=Elaeophora elaphi PE=4 SV=1
----------------------------------------KHLVVMTGAGISTESGIPDYRSPKVGQYR-T--------DH--RPVLHGDFMQSRRNYVA
WPASQPNETHQTIANWEKS-ERFTWLITQNVDGLHTAAGSKMLTELHGCSRRVICMNCHSLFSWCMDCNIIPTCPNCGPESILKTDVVFFGGIAREVNKC
YKVVESCDGMLVLGSSLTVLSGCRYVQQAYEQSVPILIVTIGPTAADDLATVKISAKCSDVIRHVPNL-----------
>tr|A0A044RVD9|A0A044RVD9_ONCVO Uncharacterized protein OS=Onchocerca volvulus GN=WBGene00238090 PE=4 SV=1
----------------------------------------RHLVVMTGAGISTESGIPDYRSPKVGQYR-T--------DH--RPVLHGDFMQSRRNFVA
WPASQPNVTHQIIANWEKS-KRFTWLITQNVDGLHTAAGSKMLSELHGCGRRVICMNCHSLYDWCLDCDIPPVCPKCGPKSILKTDVVFFGGIDPEISKC
YDMVKSCDGLLVLGSSLTVLSSYRYVQQAFEQSTPILIANIGPTAADDLATVKISAKCSDIIKHVSNL-----------
>tr|T1EG11|T1EG11_HELRO Uncharacterized protein OS=Helobdella robusta GN=HELRODRAFT_114375 PE=4 SV=1
----------------------------------------KKLLVITGAGVSTESGIPDYRSPDIGLYR-R--------TR--PILNYNDFMCSRRNFVS
WPATQPNATHKSFAHWERK-GLVHFLVTQNIDRLHMRAGSKKVVELHGNIHQVICTQCGEVTTWLKDVLVPPKCDTCG--GAMKCDVIFFGEVPQWITSV
QNLVKECDSMLVAGSSLHVYSAFHFVQLARHQDKKIAIINIGVTRADKMADIKIDAKCGDVIPHLVL------------
>tr|D7M216|D7M216_ARALL Putative uncharacterized protein OS=Arabidopsis lyrata subsp. lyrata GN=ARALYDRAFT_350148 PE=3 SV=1
----------------------------------------SRLTILTGAGISTECGIPDYRSPNGAY-S-S--------GF--KPITHQEFTRSRRSYAG
WRAAQPGPAHTALASLEKA-GRINFMITQNVDRLHHRAGS-DPLELHGTVYTVMCLDCGFSFSWAEDIEIIPVCEKCK--GVLKPDVIFFGDIPKERTQA
MEVAKQSDAFLVLGSSLMTMSAFRLVRAAHEAGAMTAIVNIGETRADDIVPLKINARVGEILHRVLDVGSLS-------
>tr|A0A059AJY0|A0A059AJY0_EUCGR Uncharacterized protein OS=Eucalyptus grandis GN=EUGRSUZ_I00121 PE=3 SV=1
----------------------------------------TKLVVLTGAGMSTECGIPDYRSPNGAY-S-T--------GF--RPITHQEFVRSRRSYAG
WRTAQPSAAHYALASLEKA-GRIDFMITQNVDRLHHRAGS-NPLEIHGTVYTVICIDCGFSFCWAADIEIIPTCQKCS--GILKPDVVFFGDVPKDWDRA
MEAARECDAFLVLGSSLMTMSAYRLIKAAHESGAATAIVNVGVTRADDLVPLKINARLGEILPRVLHTGSLS-------
>tr|D8RGY2|D8RGY2_SELML Putative uncharacterized protein OS=Selaginella moellendorffii GN=SELMODRAFT_411217 PE=3 SV=1
----------------------------------------KKLAVITGAGVSTESGIPDYRSPQGAY-S-T--------GF--KPITHQEFLKSRRSYIG
WRQTQPGPSHIALAKLEGDDARTTGMITQNVDRLHHKAGS-NPIELHGTTHQVVCLSCGNLSPWAADIEIIPACQACG--GNLKPHVVFFGDVPLDRRAA
ASMVQESDALLIVGSSVMVLSAFRLVSAAHKQGSPIAIINVGKTRADEIASFKIESTAGDVLSGFLSTQGKM-------
>tr|A9RKY5|A9RKY5_PHYPA Uncharacterized protein OS=Physcomitrella patens subsp. patens GN=SRT1504 PE=3 SV=1
----------------------------------------KRLVVITGAGTSTECGIPDYRSPHGAY-S-S--------GF--KPMTHQDFISSRRSYAG
WRSANPGPTYLSLAQLEAK-GRVKGMITQNVDRLHYKAGS-KPIELHGTTHEVICLDCGDMSDWAKDLDIIPECKKCN--GTLKPNVVFFGDVPKPRDLC
MSLARSADALLVVGSSVMTMSALRLVRAAADMGSPIAILNIGPTRADDLAHFKINARSGEVLPRLLNMGSMS-------
>tr|B7G335|B7G335_PHATC Predicted protein (Fragment) OS=Phaeodactylum tricornutum (strain CCAP 1055/1) GN=PHATRDRAFT_21543 PE=4 SV=1
----------------------------------------SQILCLTGAGLSTESGIPDYRGNNG-SYH-R--------GH--KPMVHDQFMKSRRGMVG
WKETAPNAGHVALTELERL-GRKLSLITQNVDTLHRRAGTKHLIELHGRTDQLECMQCGTKRDWLNDAAVVPPCQSCG--GFMKPSVVFFGDVPRNRAQC
QTAVEKADGLLVVGSSLAVHSAFRHVRAASKLGVPIAILNVGGTRAEGLDVLKIEAPTGQTLEGVAKV-----------
>tr|W9SBN3|W9SBN3_9ROSA NAD-dependent ADP-ribosyltransferase sirtuin-4 OS=Morus notabilis GN=L484_027147 PE=3 SV=1
----------------------------------------KKLVVLTGAGISTECGIPDYRSPNGAY-S-S--------GF--KPITHQEFLRSRRSYAG
WRAAQPGAAHIALASLEKA-GRINFMITQNVDRLHHRAGS-NPLELHGTVYSVVCLDCGFSFSWAADVEIIPTCQKCN--GVLKPDVIFFGDVPKERDMS
IEAAKECDAFLVLGSSVMTMSAYRLVRAAHEAGAATTIVNVGETRADDFVPLKINARLGEILPRVLHFGSLS-------
>tr|W1PNP1|W1PNP1_AMBTC Uncharacterized protein OS=Amborella trichopoda GN=AMTR_s00017p00253090 PE=3 SV=1
----------------------------------------EKLMVLTGAGISTESGIPDYRSPNGAY-S-S--------GF--KPITHQEFVRSRRSYAG
WRAAQPGATHKALASLEMQ-GRVKFMATQNVDRLHHRAGS-EPLELHGTVYSVVCLGCGFTFCWALDIEIIPNCLKCD--GLLKPDVVFFGDVPKDRGKA
MEAAKSCDALLVVGSSLMTMSAFRLVRAAYEVNATVAIINIGETRADELVSLKISARSGEILPRLLGMGCLS-------
>tr|A0A0K9R8J8|A0A0K9R8J8_SPIOL Uncharacterized protein OS=Spinacia oleracea GN=SOVF_094770 PE=3 SV=1
----------------------------------------NKLVVLTGAGMSTESGIPDYRSPNGAY-S-T--------GF--KPITHQEFVRSRRSYAG
WRSAQPGAGYFALASLEKA-GRISYMITQNVDRLHHRAGS-NPLELHGTVYTVGCIECGHSFCWAADIDIIPTCPKCD--GVLKPEVVFFGDVPKDREIA
METATNCDALLVIGSSLMTFSAFRLVRAAHEAGASTAIINVGISRADDIVPLKISARCGEILPRLLDTGSLS-------
>tr|M1D608|M1D608_SOLTU Uncharacterized protein OS=Solanum tuberosum GN=PGSC0003DMG400032556 PE=3 SV=1
----------------------------------------TKLVVLTGAGMSTESGIPDYRSPNGAY-S-T--------GF--KPITHQEFLRSRRSYAG
WRAAQPSTGHIALSSLEKA-GHISFLITQNVDRLHHRAGS-NPLELHGTVYIVACTNCGFSLPWAEDIEIIPECQSCQ--GVLKPDVVFFGDVPKSRDAA
MEAAKGCDAFLVLGSSLMTMSAFRLIKAAREAGAATAIINIGATRADDIVPLKISARVGEILPRLLSIGSLS-------
>tr|I1JXZ2|I1JXZ2_SOYBN Uncharacterized protein OS=Glycine max GN=GLYMA_04G210000 PE=3 SV=1
----------------------------------------TKLTVLTGAGISTECGIPDYRSPNGAY-S-S--------GF--KPITHQEFLRSRRSYAG
WRTAQPSAAHTALATLDKA-GRINFMITQNVDRLHHRAGS-NPLEIHGTVYTVICIDCGYSFCWAEDIEIIPTCHKCN--GALKPDVVFFGDVPKDRDMA
MEASRRCDAFLVLGSSLMTMSAFRLIRAAHEAGAATAIVNIGVTRADDFVPLKINARLGEILPRVLDIGSIS-------
>tr|G8A1N0|G8A1N0_MEDTR NAD-dependent deacetylase OS=Medicago truncatula GN=MTR_3g096710 PE=3 SV=1
----------------------------------------TKLVVLTGAGISTECGIPDYRSPNGAY-S-S--------GF--RPITHQEFLRSRRSYAG
WRAAQPSAAHCALAAFENA-GRVDFMVTQNVDRLHHRAGS-NPLELHGTVYNVICINCGYSLCWAEDIEIIPTCQKCN--GVLKPDVVFFGDVPKERDMA
MEASRSCDAFLVLGSSVMTMSAFRLVRAAHEAGAATAIVNVGVTRADDFVPLKINARLGEILPRVLDMGSIS-------
>tr|D9IPD0|D9IPD0_CHLRE Sir2-like protein OS=Chlamydomonas reinhardtii GN=SRT1 PE=2 SV=1
----------------------------------------SRLVVLTGAGCSTESGVPDYRSPQG-AYS-T--------GF--KPMTHQQFLASRRSFYG
WPATQPNSAHVALAELEQR-GWVQGLITQNVDRLHTAAGSRNVIELHGSSHDVICLGCGRRSSAAADVELLATCSGCGD-GPLKPDVVFFGDIPPERDRA
ADLAGGCDALLVVGSSVQVYSAFRLVEAARGAGARVLIVNVGPTRADKLADFKLEARAGEVLTRLSRHPQLL-------
>tr|D8U497|D8U497_VOLCA Putative uncharacterized protein OS=Volvox carteri GN=VOLCADRAFT_63648 PE=3 SV=1
----------------------------------------KRLVVLTGAGCSTESGVPDYRSPQG-AYS-T--------GF--KPMTHQQFLASRRSFYG
WPATQPNEAHLALADLERR-GWVSGIVTQNVDRLHTRAGSREVLELHGSSHDVVCLDCGRLSPVAADVELVAPCRDCG--GTLKPDVVFFGDLPQERERA
AALIASSDTLLVVGTSVMVYSAYRLVEAAKAAGAKLLIVNVGHTRADKLADVKVEARAGEVLVRLARHSALQ-------
>tr|V4T716|V4T716_9ROSI Uncharacterized protein OS=Citrus clementina GN=CICLE_v10001356mg PE=3 SV=1
----------------------------------------AKLIVLTGAGISTECGIPDYRSPNGAY-S-S--------GF--KPITHQQFFRSRRSYAG
WRAAQPNPAHFALASLEKA-GRIDCMITQNVDRLHHRAGS-NPLELHGTVYTVVCLDCGFSFCWAEDIEIIPTCQKCN--GVLKPDVVFFGDVPKDRDKA
MEAAKECDAFLVLGSSLMTMSAYRLVRAAHEAGSTIAIVNVGETRADDLTTLKISARLGEILPRVLDVGSLG-------
>tr|U5GAX6|U5GAX6_POPTR SIR2-family protein OS=Populus trichocarpa GN=POPTR_0005s06930g PE=3 SV=1
----------------------------------------TKLVVLTGAGISTECGIPDYRSPNGAY-S-S--------GF--RPITHQEFVRSRRSYAG
WRAAEPSAAHFALASLEKA-GRIDFMITQNVDRLHHRAGS-NPLEIHGTVYSVTCLDCNFSFPWAEDIEIIPACPKCN--GVLKPDVVFFGDVPKDRDKA
MDAAKGCDAFLVLGSSLMTMSAFRLVRAAHEAGAATAIVNLGVTRADDIVPLKINARLGEILPRVLNIGSLS-------
>tr|M5WG27|M5WG27_PRUPE Uncharacterized protein OS=Prunus persica GN=PRUPE_ppa007526mg PE=3 SV=1
----------------------------------------TKLMVLTGAGISTECGIPDYRSPNGAY-S-S--------GF--RPITHQEFLRSRRSYAG
WRAAHPGPAHIALASLEKA-GRINCMITQNVDRLHHRAGS-NPVELHGTVYSVVCIECGFSFPWAEDIEIIPTCQKCN--GVLKPDVVFFGDVPKDRDKT
IQAAKECEAFLVLGSSVMTMSAYRLVRAAHEAGAATAIVNVGVTRADDFVPLKINARLGEILPRVLDMGSLC-------
>tr|A0A0A0LK90|A0A0A0LK90_CUCSA Uncharacterized protein OS=Cucumis sativus GN=Csa_2G336650 PE=3 SV=1
----------------------------------------SKLVVLTGAGISTECGIPDYRSPNGAY-S-S--------GF--KPITHQEFVRSRRSYAG
WREAQPGPAHLSLASLEKV-GRINLMVTQNVDRLHHRAGS-DPLELHGTVYSVICLECGFSICWAEDIEIIPTCQKCN--GVLKPDVVFFGDVPKDRNKA
MEAAKNCDAFLVLGSSVMTMSAYRLVRAAHEAGAATGIVNVGVTRADDFVSMKINARLGEILPRVLHIGSLS-------
>tr|A0A0J8CPW0|A0A0J8CPW0_BETVU Uncharacterized protein OS=Beta vulgaris subsp. vulgaris GN=BVRB_4g078680 PE=3 SV=1
----------------------------------------EKLVVLTGAGMSTECGIPDYRSPNGAY-S-S--------GF--KPITHQEFVSSRRSYAG
WRSAQPGAGYFALASLEKA-GRISFMITQNVDRLHHRAGS-NPLELHGTVYTVGCLECGYSFCWAEDIDIIPTCPECD--GVLKPDVIFFGDVPKDRDRA
MEAAKSCDAFLVIGSSVMTFSAFRLVRAAHEAGAATAMINIGSTRADNIVSLKIGARCAEILPRLLHTGSLC-------
>tr|A0A061DJX4|A0A061DJX4_THECC Sirtuin 2 OS=Theobroma cacao GN=TCM_001561 PE=3 SV=1
----------------------------------------TKLVVLTGAGISTECGIPDYRSPNGAY-S-S--------GF--KPITHQEFVRSRRSYAG
WRAAKPGAAHVALASLEKA-GRINFMITQNVDRLHHHAGS-NPLELHGTVYSVICLDCGFSFCWAADIEIIPTCQRCK--GTLKPDVVFFGDVPKERDKA
MEVSRECDGFLVLGSSLMTMSAYRLVRAAHKAGATTAIVNIGTTRADDIVSLKLNARLGEILPRVLNTGSLS-------
>tr|A0A067K333|A0A067K333_JATCU Uncharacterized protein OS=Jatropha curcas GN=JCGZ_19292 PE=3 SV=1
----------------------------------------SNLMVLTGAGISTECGIPDYRSPNGAY-S-S--------GF--KPITHQEFLRSRRSYAG
WKAAQPGAAHFALASLEKA-GRINFIVTQNVDRLHHRAGS-NPLELHGTVYSVICLDCGFSFSWATDIEIIPTCQKCN--GVLKPDVVFFGDVPKDRDKA
MEAAKGCDAFLVLGSSVMTMSAYRLVRAAHEAGAAMAIVNLGVTRADDFVPLKINARLGEILPRVIDIGSLS-------
>tr|D7SWF4|D7SWF4_VITVI Putative uncharacterized protein OS=Vitis vinifera GN=VIT_07s0031g02510 PE=3 SV=1
----------------------------------------SKVVVLTGAGISTECGIPDYRSPNGAY-S-S--------GY--KPITHQEFVRSRRSYAG
WKAAQPGASHSALASLEKA-GRINYIITQNVDRLHHRAGS-SPLELHGTVYSVVCLDCGYLINWAADIEIIPTCQKCK--GVLKPDVVFFGDIPKDRADA
MAAVRGCDALLVVGSSLMTMSAFRLVRAAHEAGAATAIVNVGNTRADDFVSLKINARCGEILPRLLDIGCLS-------
>tr|A0A0D1PJB9|A0A0D1PJB9_9RHIZ Contig120, whole genome shotgun sequence OS=Mesorhizobium sp. UASWS1009 GN=QV13_17140 PE=4 SV=1
-----------------------------------QLLRL-KPLVLTGAGMSTDSGIPDYRGPEGSLRHSRP---MTYQEFLHDDAARHRYWARSWQHMN
--AANPHAGHNIIAKWNTE-GHIAGVVTQNVDGLHQQSQRGPIIALHGSMDEIECLVCGVKENRDGDARIPQHCLNCGS-DKLKPTVVYFGEIPKRKEAI
QTLLDRSGALIVIGSSLAVMSGYRILLEADRARKPIGIINLGPTRGEERATFRWRSGVKQALEWLDQE-----------
>tr|A0A0M2X8H7|A0A0M2X8H7_9CORY NAD-dependent protein deacetylase OS=Corynebacterium minutissimum GN=WU87_08790 PE=4 SV=1
-----------------------------------DQLRRGNVMVLTGAGVSTESGVPDYRGPHGSLSRHRP---MTYQEFLHDPQASHRYWARAWRVMQ
--AAHPNRTHYALVELERA-GLLTGVVTQNVDGLHEEAGQRNLIALHGDMQHVVCLSCGYEETRDGDVALSQGCVRCGS-QRLKPDVVYFGEPPTKKDAA
YAMVNESDSLLVAGSSLAVMSGFRFVLEAKKQGKRVATINGGPGRADDRVDTLWRTQVGPAFDAVLDE-----------
>tr|A0A0K2X0R4|A0A0K2X0R4_CORST NAD-dependent protein deacetylase 1 OS=Corynebacterium striatum GN=cobB PE=4 SV=1
-----------------------------------EQLRAGGVMVLTGAGVSTDSGVPDYRGPQGSLSRHTP---MTYQEFCYDSAASHRYWARSWRVMD
--AARPNRTHYALVELECA-GLLSGIVTQNVDGLHKEAGTETLIPLHGDMEHVVCLNCGYAEDRDGDVALSQPCIRCGS-ELLKPDVVYFGEPPARRDAA
RDLLARSSSLIVVGSSLAVMSGYRFMLDALKQGKEVSVINGGPGRGDPKATTLWRAQVAPAFDELLDL-----------
>tr|G0HDB1|G0HDB1_CORVD NAD-dependent protein deacetylase OS=Corynebacterium variabile (strain DSM 44702 / JCM 12073 / NCIMB 30131) GN=cobB PE=3 SV=1
-----------------------------------SQLRQGGVLVITGAGVSTDSGIPDYRGPQGSLGRHRP---MTYQEFRHDPAASHRYWARSWREMA
--SARPNATHYAVAELEDA-GMVSGVVTQNVDGLHASAGSRNLLTLHGDLARVICLECGHTEDRDGDVTLDAGCEVCGS-VLLKPDVVYFGEPPVRRERA
AEMVEKASSVLVAGSSLAVMSGYRLVLAAQQQGKQVSVINGGPGRADAKVDVLWRTSVAPAFLDLLDE-----------
>tr|E1VYN2|E1VYN2_ARTAR Putative NAD-dependent deacetylase OS=Arthrobacter arilaitensis (strain DSM 16368 / CIP 108037 / JCM 13566 / Re117) GN=npdA PE=
-----------------------------------QMLAAGRVLVVTGAGVSTDSGIPDYRGPQGSLQRHRP---MTFQEFRYRPEARQRYWARGWRHMD
--KAEPNQIHRRLVQWEET-GKISGIVTQNVDGLHRQAGSRRVIPVHGDLSIVRCLDCGNSENRDGDVELPQSCLRCGS-LALKPDVVYFGESPVRKERI
AALEAESDALLVMGSSLAVMSGYKILLNFVKRELPVALITNGHVRGEQKATWRWRVPLEQALRQLD-------------
>tr|S4XCB5|S4XCB5_9CORY NAD-dependent protein deacetylase OS=Corynebacterium terpenotabidum Y-11 GN=cobB PE=3 SV=1
-----------------------------------AQLRDGGVLVITGAGVSTESGIPDYRGPHGSLGRHRP---MTYQEFRHDPAASHRYWARSWREMA
--TARPNPTHYAIAELEDA-GLVTGVVTQNVDGLHAAAGSRSLLALHGDLARVICLQCGHTEDRDGDVTLDDGCAACGS-ELLKPDVVYFGEAPTRRHRA
AQMLEDASSVLVAGSSLAVMSGYRLILDAQKQGKQVSVINGGPGRADDRVDILWRTSVTPAFLGLIDG-----------
>tr|A0A0G3GMJ4|A0A0G3GMJ4_9CORY NAD-dependent protein deacetylase, SIR2 family OS=Corynebacterium epidermidicanis GN=cobB1 PE=4 SV=1
-----------------------------------GQLRSGGVLVITGAGVSTDSGIPDYRGPNGSLTRHRP---MTYQEFKHDPAALQRYWARSWRHMA
--AARPNRTHFALSELEQS-GFVSGVITQNVDGLHMAAGSKNVLALHGSLADVVCLNCGNLEDRDGDVALSDGCLSCGS-TLLKPNVVYFGEPPARKAQA
KEMLLAAKSVLAVGTSLAVMSGLRLVLDAEKQGKVVSVINGGPGRADPRAKVVWRTAVGPAFDALLDE-----------
>tr|W5XWU1|W5XWU1_9CORY Uncharacterized protein OS=Corynebacterium vitaeruminis DSM 20294 GN=B843_00425 PE=4 SV=1
-----------------------------------AQLRAGDVLVVTGAGVSTDSGIPDYRGPRGSLSRHRP---MTYQEFRYDPAALHRYWARSWRHMD
--SARPNRVHELFALWEGK-GLVSGVVTQNVDGLHQAAGSRNVVALHGDLSTVVCLSCGFHEPRDGDVTLGEGCLRCGS-RLLKPDVVYFGEPPVRKEKA
AALLAGSRSVLVAGSSLAVMSGLRIVIDAQKQGKEVAVINGGPGRADERVDVVWRTQLRPALEALSLR-----------
>tr|A0A072Z3V1|A0A072Z3V1_CORGT NAD-dependent protein deacetylase OS=Corynebacterium glutamicum ATCC 14067 GN=KIQ_004320 PE=4 SV=1
-----------------------------------KQLKAGNVLAVTGAGVSTDSGIPDYRGPKGSLSRHRP---MTYQEFRHDPAASHRYWARSWRVMD
--QARPNRTHYAMVELEQH-GFLSGVVTQNVDGLHAEAGTKNLVALHGDLAHVMCLNCGFGEDRDGDVFLDEGCLRCGS-LMLKPDVVYFGEPPARKKDL
KKLLDASSSLLIAGSSLAVMSGYRIVIEAQRQGKQVSVINGGPGRADSRVDILWRTRVAPAFDDILDA-----------
>tr|X5DSB2|X5DSB2_9CORY NAD-dependent protein deacetylase 1 OS=Corynebacterium glyciniphilum AJ 3170 GN=cobB1 PE=4 SV=1
-----------------------------------DQLRQSPALVVTGAGVSTDSGVPDYRGPSGSLTRHRP---MTFQEFRHDPDASHRYWARSWRRMA
--AARPNLTHYILTELEQA-GLVTGVVTQNVDGLHADAGTRNLLTLHGDLSRVICLRCGCLEDRDGDVTLDEGCRQCGS-VLLKPDVVYFGEPPHRKQRA
SRMLTDASSLLVVGSSLAVMSGYRLVLDAQKQGKTVSVINGGPGRADPKADIVWRTAVGPAFLNLIDA-----------
>tr|S5TFZ9|S5TFZ9_9CORY Sir2-like regulatory protein OS=Corynebacterium maris DSM 45190 GN=B841_00525 PE=4 SV=1
-----------------------------------AQLRAGPALVLTGAGVSTDSGIPDYRSAGGRLRTGRP---MTYQEFRHDPAASHRYWARGWRTMR
--AAHPNRTHYALVELERA-GLLRGVVTQNVDGLHRAAGTERLIHLHGDMEHVVCLDCGAVEDRDGDVTLDQGCHVCGS-RRLKPDVVYFGESPARRHAA
DRLLAESSSLLIAGSSLAVMSGYRFVLEARKAGKRVAVINGGPGRGDAKADTVWRTRVGPAFDDLLDA-----------
>tr|A0A0B2AQI5|A0A0B2AQI5_9MICC NAD-dependent protein deacetylase OS=Sinomonas sp. MUSC 117 GN=cobB PE=3 SV=1
-----------------------------------SMLGGGGVMALTGAGVSTASGIPDYRGPQGSWRKHRP---MTYQEFRHDPAARHRYWARSWRHID
--RARANSAHRILAQLETR-GVLLGVVTQNVDGLHAAAGSRNLVSLHGDLDKVVCLNCGNVEGRDGDVELPQGCLVCGS-VELKPDVVYFGESPIRKERA
TAMLAQARSLLVLGSSLAVMSGFRFVLDAVRDGKPVGIVNAGPTRGDRRAHWRWRSDVGEALEDLASS-----------
>tr|A0A095ZLD3|A0A095ZLD3_9MICC NAD-dependent protein deacetylase OS=Arthrobacter albus DNF00011 GN=HMPREF2128_10000 PE=4 SV=1
-----------------------------------RMVRGGKVLILTGAGVSTDSGIPDYRGPQGSLRRTRP---MTVQEFRADPAARKRYWARAHRLMN
--QARPNLGHRVLAEWQRR-GLLSGIVTQNVDGLHEQAGAADVIALHGDMSEVECLDCGATEPRDGDVTLSDACAVCGS-ERMKPSVVYFGENPKRRERV
EELKADSDALLVVGSSLAVMSGYRFVLDAIKRGQPTATITAGPGRADDKVDVLWRTLATPALLEVEAR-----------
>tr|D5NW99|D5NW99_CORAM NAD-dependent protein deacetylase OS=Corynebacterium ammoniagenes DSM 20306 GN=cobB PE=3 SV=1
-----------------------------------KQLRRGPAVVLTGAGVSTDSGIPDYRGPQGSLSRHRP---MTYQEFRYDPVASHRYWARSWRVMN
--QAQPNRTHHALVELERA-GLINGVITQNVDGLHKLAGTHTLVALHGDMETVMCLECGNIEDRDGDVTLDDGCTRCGS-KLLKPDVVYFGESPHRKADA
YSLLDAASSLLVAGSSLAVMSGMRFVLEARKQDKPVAIINGGPGRADTRADILWRTQVGTAFDALLDE-----------
>sp|Q8FUC8|NPD1_COREF NAD-dependent protein deacetylase 1 OS=Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 10039
-----------------------------------KLLEAGSVLAVTGAGVSTDSGIPDYRSPRGSLNQGRP---MTYQEFRFDPVASHRYWARSWRVMA
--DAQPNRTHYALVELERA-GLLSGIVTQNVDGLHRRAGSENLVALHGDLATIVCLQCGHREARDGDVTLDDGCARCGS-VLLKPDVVYFGEPPSRKTRV
AQLLDGADAVVVAGSSLAVMSGYRIVIEAQRAGKPVAVINGGPGRADHRVDILWRTRVGPAFDQILDA-----------
>tr|A0A0F6QUZ8|A0A0F6QUZ8_9CORY NAD-dependent protein deacetylase OS=Corynebacterium camporealensis GN=cobB1 PE=3 SV=1
-----------------------------------EQLRAGKVMVLTGAGVSTDSGVPDYRGPQGSLSRHRP---MTYQEFRYDQAASHRYWARSWRVMD
--AAVPNRTHYALVELERA-GLVSGVLTQNVDGLHKEAGTQRLVTIHGDMESVNCLECGQQEERDGDVALNDGCTRCGS-RLLKPDVVYFGEPPVRKEAA
YALLDDSASVLVAGSSLAVMSGYRFVLDALKAGKRVAVINGGPGRGDARVDTLWRTQVGPAFDAVLDE-----------
>tr|D7WBM6|D7WBM6_9CORY Transcriptional regulator, Sir2 family OS=Corynebacterium genitalium ATCC 33030 GN=HMPREF0291_10515 PE=4 SV=1
-----------------------------------RMLNRGPALILTGAGMSTESGIPDYRSPGGRLSKGRP---MTYQEFAHSPAAVRRYWARAMRYMR
--AAHPNRAHFALVELERA-GLIRGIVTQNVDGLHLEAGSQNVIALHGDMEHVVCLDCGRRETRDGDVELPDTCGACGG-QRLKPDVVYFGENPRRRAEA
GQWLAESTSLIAVGTSLAVMSGYRLVLDARAQEKPAAVVNGGPGRADQKVTTVWRSNVGDALDSILDE-----------
>tr|A0A076NKB6|A0A076NKB6_9CORY NAD-dependent protein deacetylase OS=Corynebacterium imitans GN=CIMIT_00390 PE=4 SV=1
-----------------------------------EQLRAGKVLVITGAGVSTDSGIPDYRSAGGRLTKGRP---MTYQEFAHSPTQVRRYWARAMQFMR
--AAAPNRTHFALVELERA-GLLTGIVTQNVDGLHAQAGSRKVIALHGDMEKVVCLDCGARHARDGDVELRADCPTCGG-QRLKPSVVYFGENPRRRQAA
HDWLEESNSVLALGTSLAVMSGYRFVIDARKQGKPVSVVNGGPGRGDPKATTLWRTGVAEAMDAILDG-----------
>tr|A0A077HMT7|A0A077HMT7_9CORY NAD-dependent protein deacetylase OS=Corynebacterium ureicelerivorans GN=CUREI_00290 PE=4 SV=1
-----------------------------------AQLRNPKTLIITGAGISTDSGIPDYRSANGRLTKGRP---MTFQEFAHSPAQVHRYWARAMHYMR
--QAQPNRAHYALVELERA-GLIRGIVTQNVDGLHTQAGSDNVIALHGDMEHVVCLDCGALHERDGDVELKDACPTCQG-QRLKPHVVYFGENPKRRQAA
AQWLEESTGVIAIGTSLAVMSGYKFILDARKQGKPTAVINGGPGRADGKVDTLWRTRVADALDEILDG-----------
>tr|C0XTR4|C0XTR4_9CORY Transcriptional regulator, Sir2 family OS=Corynebacterium lipophiloflavum DSM 44291 GN=HMPREF0298_1834 PE=4 SV=1
-----------------------------------SMLRHPRVLVLTGAGISTESGIPDYRSPGGRLTKGRP---MTYQEFAHSPTAVRRYWARAIRFMR
--AAKPNRAHFALVELERA-GLLSGIVTQNVDGLHREAGSEGVIALHGDMDCVVCLDCRSREQRDGDIELRSPCSSCGS-TRVKPDVVYFGENPRRRARA
AEMLQNSTGVIAMGTSLAVMSGYRLVLDALAQGKEVAVINAGPGRADPKVDVVWRANVGDALGLVLDG-----------
>tr|A0A010PIL4|A0A010PIL4_9MICC NAD-dependent protein deacetylase OS=Nesterenkonia sp. AN1 GN=BG28_08805 PE=4 SV=1
-----------------------------------RMLQSGDVLCVTGAGVSTDSGIPDYRGPQGSLHRHRP---MTYQEFQHDAASRRRYWARGWRQMH
--QAEPNHAHRLLADWQSE-GLLSGLITQNVDGLHRAAGADPVIHLHGDMDSVICLRCDNREARDGDVTLDQTCLVCGS-EKLKPDVVYFGESPARKAAV
EGLVAASSALLVVGSSMAVMSGFKIALTMHQSGRPIGVINGGPSRADTKADWRWRTRIAPALQTLDAL-----------
>tr|A0A011NYC8|A0A011NYC8_9PROT NAD-dependent protein deacetylase OS=Candidatus Accumulibacter sp. SK-12 GN=cobB_1 PE=4 SV=1
-----------------------------------LRLRGAPVVVLSGAGLSTASGIPAYRDRDGRWQQPAP---MQHRDFLASAAARQRYWARSWRRMG
--LASPAPGHRVLREMERR-GIVSSVITQNVDGLHQKAGSRRVIELHGGIGRVRCLACGERFARDGDAQVADDCPHCG--GMLKPDVVFFGDSPRRVSAA
LRAIDAAHALLVVGSSLMVYSGFRLADYAHRQGRPVLAINDGVTRADHLLEVKVASECGAVLERLLAR-----------
>tr|A0A011QB09|A0A011QB09_9PROT NAD-dependent protein deacetylase OS=Candidatus Accumulibacter sp. SK-11 GN=cobB_1 PE=4 SV=1
-----------------------------------GRLRDAPPVVISGAGLSTASGIPAYRDHHGHWQQPTP---IQHRDFLNSPSVRQRYWARSWPRMG
--LASPAPGHRVLSEMERR-GLVSSVITQNVDGLHQKAGSQRVIELHGGIARVLCLACGQRFARDGDAQVADDCPACG--GILKPDVVFFGDSPRRIAAA
TRAIDAAQELLVVGSSLMVYSGFRFADYAHRQGKPVLAINHGVTRADHLLELKIEGECGAILERLLAL-----------
>tr|M7MR51|M7MR51_9MICC NAD(P)(+)-protein-arginine ADP-ribosyltransferase OS=Arthrobacter gangotriensis Lz1y GN=ADIAG_01615 PE=4 SV=1
-----------------------------------RMLEAGSVLVLTGAGVSTDSGIPDYRGPNGSLLRHRP---MTYQEFLHDPHARHRYWARSWRHMA
--LASPNSSHRRLATWEAT-GKLSGIVTQNVDGLHVAAGSMNVIALHGDLEQISCLNCGALEGRDGDVSLDEGCLVCGS-PALKPNVVYFGENPARKARL
KELQARSASLLVIGSSLAVMSGYKLLLDARAAGKPVGLINGGPTRGDAKSDYRWRSNIAEALERLDA------------
>tr|A0A0N9JPG6|A0A0N9JPG6_9MICC NAD-dependent protein deacetylase OS=Arthrobacter arilaitensis GN=AOZ07_13015 PE=4 SV=1
-----------------------------------QMLNSGSVLVVTGAGVSTDSGIPDYRGPNGSLQRHRP---MTYQEFRYRPEARQRYWARGWRHMD
--KAEPNQIHRRLVQWEQE-GKITGIITQNVDGLHQQAGSKRVIPVHGDLSTVRCLNCGFSEDRDGDVELPQRCLNCDS-YALKPDVVYFGESPPRKELM
AALEAESSALLVLGSSLAVMSGYKVLLNFVKRELPVALITNGHVRGEQKATWRWRVPLETALSQLT-------------
>tr|A0A0M4JFI2|A0A0M4JFI2_9MICC NAD-dependent protein deacetylase OS=Arthrobacter sp. LS16 GN=AFL94_12955 PE=4 SV=1
-----------------------------------SMLDEGKVLVVTGAGVSTDSGIPDYRGPNGSLQRHRP---MTFQEFRYRPEARQRYWARGWRHMG
--NAEPNDIHRRLVQWERE-GRINGIITQNVDGLHQQAGSRRVIPVHGDLSIVRCLDCGHTEDRDGDVELPQACENCGS-LVLKPDVVYFGESPPRKEAM
AQLQAESTSLLVLGSSLAVMSGYRILLDFVKLGLPVALITNGHVRGEQKATWRWRVPLGQALDQLS-------------
>tr|D3LKX1|D3LKX1_MICLU Transcriptional regulator, Sir2 family OS=Micrococcus luteus SK58 GN=HMPREF0569_2088 PE=4 SV=1
-----------------------------------RLMEESRPLVITGAGVSTDSGIPDYRGPNGSLHRHRP---MTYQEFRDDPAARHRYWARSWRRMD
--QARPNEAHRILARWAAE-GRIAGILTQNVDGLHAEAGRDRLIELHGNLARVACLNCGATESRDGDVSLDQGCRVCGS-VKLKPDVVYFGESPARRAAA
EAMADDGGAVLAVGTSLAVMSGYRFVLRAERAGHETGLINLGPTRADAKARWRWRAPVADALAWLDAR-----------
>tr|A0A0K1RD51|A0A0K1RD51_9CORY NAD-dependent protein deacetylase OS=Corynebacterium riegelii GN=AK829_09630 PE=4 SV=1
-----------------------------------NQLQNPKNLVITGAGVSTASGIPDYRSKNGRLTKGRP---MTFQEFAHSPQQVRRYWARAIRMMR
--AAAPNRAHFALVELERA-GLLTGLVTQNVDGLHTQAGSQNVIALHGDMDHVVCLDCHTLHERDGDVELPAGCPTCRS-ERLKPNVVYFGENPKRRAQA
DRWLAQSTGVIAIGTSLAVMSGYKFIIDATKQGKPVTVINGGPGRGDVKADTVWRTDVGEALDEILDG-----------
>tr|A0A0K2H2D0|A0A0K2H2D0_9CORY NAD-dependent protein deacetylase OS=Corynebacterium lactis RW2-5 GN=cobB PE=3 SV=1
-----------------------------------EMLSDAPALVLTGAGVSTDSGIPDYRGPRGSLSRHRP---MTYQEFRYDSAASHRYWARSWRIMD
--RARPNRTHFAIAELERH-GFARGVVTQNVDGLHAQAGTKNVVPLHGDLATVICLYCGSREDRDGDVDLSAGCEHCGS-TMLKPDVVYFGEPPARKEAA
TKMLEEAGSLLVAGSSLAVMSGYKFVIDAQRADKPVAVINGGPGRADGRVQTLWRTPVAPAFDALLDA-----------
>tr|E0DHM3|E0DHM3_9CORY Transcriptional regulator, Sir2 family OS=Corynebacterium matruchotii ATCC 14266 GN=HMPREF0299_5178 PE=4 SV=1
-----------------------------------KQLQAGNVLVVTGAGVSTDSGIPDYRGPGGSLRHHRP---MTYQEFRGDDHARRRYWARSWRHLA
--GAQPNYVHRCLSTLEAT-GHLTGIVTQNVDGLHQAAGSRTVIPLHGDLATVICLSCGAREDRDGDVQLADGCARCGS-ALMKPDVVYFGEPPRRKQQV
ANLIDQSDSVLVVGSSLAVMSGMRIILDAKKQHKQVSVMNGGPGRADDRVDVLWRTDLATAFRQIMPQ-----------
>tr|E2S0Q1|E2S0Q1_9CORY NAD-dependent protein deacetylase OS=Corynebacterium pseudogenitalium ATCC 33035 GN=cobB PE=3 SV=1
-----------------------------------KQLREGPVMVLTGAGVSTDSGVPDYRGPRGSLSRHRP---MTYQEFRHDPAASHRYWARSWRVMD
--SAVPNRTHYALVELERA-GLVNGVVTQNVDGLHKQAGTANLVALHGDMETVVCLMCGQREARDGDVTLDEGCERCGS-ALLKPDVVYFGEPPPRRDAA
FAVLGQARSLMVAGSSLAVMSGYRFVLEAKKQGKRVAVINGGPGRGDQKVDTLWRTQVGPAFDALLDE-----------
>tr|A0A0G3H2A5|A0A0G3H2A5_9CORY NAD-dependent protein deacetylase OS=Corynebacterium testudinoris GN=cobB1 PE=3 SV=1
-----------------------------------EQLDQGPAMVLTGAGVSTDSGIPDYRGPRGSLTRHRP---MTYQEFSHDPAASHRYWARSWRQMD
--AARPNRTHFALVELERA-GVISGVVTQNVDGLHRAAGSRTLVHLHGDLDTVICLNCRMREPRDGDVTLPEGCVRCGS-KRLKPDVVYFGEPPARKARA
SEILSQSASLIVAGSSLAVMSGYRFALDARRQRKPLAIINGGPGRADAQATTLWRTQVAPAFDELLDA-----------
>tr|A0A0B6TQ48|A0A0B6TQ48_9CORY NAD-dependent protein deacetylase OS=Corynebacterium marinum DSM 44953 GN=cobB1 PE=3 SV=1
-----------------------------------GQLGRGPSLVLTGAGVSTDSGIPDYRGPRGSLSRHRP---MTYQEFRHDPAASQRYWARSWRQMY
--VAEPNRTHFALVELERA-GLLRGLVTQNVDGLHRAAGSGNLLHLHGDLDTVMCLDCGRREDRDGDVTLPQGCVRCGS-RRLKPDVVYFGEPPQRKQDA
ARMLDGAASLLVVGSSLAVMSGYRFVLDAQRQGKAVSVINGGPGRADHRVDVLWRTPVAPAFDALLDA-----------
>tr|S2YY13|S2YY13_9CORY Uncharacterized protein OS=Corynebacterium pyruviciproducens ATCC BAA-1742 GN=HMPREF1219_01453 PE=4 SV=1
-----------------------------------QQLRAKNCLILTGAGVSTDSGIPDYRGPNGSLTRHRP---MTYQEFQHDPEALRRYWARSWRHMD
--EAEPNEVHRAIAALERE-GYVCGVITQNVDGLHMEAGSHTVIPLHGDLATVVCLACGHREDRDGDVALKEHCVNCGS-MKLKPDVVYFGEPPARKAQG
RALLDASRSLLIVGSSLAVMSGYKFVLDAKAQGKPVAVINGGPGRADAKAAVVWRTDVAHAFKEITAA-----------
>tr|C2GEI0|C2GEI0_9CORY NAD-dependent protein deacetylase OS=Corynebacterium glucuronolyticum ATCC 51866 GN=cobB PE=3 SV=1
-----------------------------------RQLRATGCLVLTGAGVSTDSGIPDYRGPNGSLTRHRP---MTYQEFQHDPEALRRYWARSWRHMD
--EARPNSVHRAIAALEAR-GFVSGLITQNVDGLHTQAGSRTVIPLHGDLGSVCCLTCGHREKRDGDVALRDECENCGS-TKLKPDVVYFGEPPARKARA
RELLDKSSSLLVVGSSLAVMSGYTFVLDARAQGKPVAVINGGPGRGDKKADVVWRTDVASAFEQISAA-----------
>tr|A0A0B5CZY9|A0A0B5CZY9_9CORY NAD-dependent protein deacetylase OS=Corynebacterium humireducens NBRC 106098 = DSM 45392 GN=cobB PE=3 SV=1
-----------------------------------AQLAEGPALVLTGAGVSTDSGIPDYRGPRGSLSRHRP---MTYQEFSHDPAASHRYWARSWRQMD
--DARPNRTHFALVELEHA-GYVGGLVTQNVDGLHRDAGTENLLHLHGNLDTVMCLECGAREDRDGDVTLPQGCLRCRS-RRLKPDVVYFGEPPARKERA
AEMLEGAASLLVVGSSLAVMSGYRFVLEAQRQGKRVAVVNGGPGRADGRVDVLWRTPVAPAFDDLLDE-----------
>tr|M1URE6|M1URE6_9CORY NAD-dependent protein deacetylase OS=Corynebacterium callunae DSM 20147 GN=cobB PE=3 SV=1
-----------------------------------KLLKAGDVLALTGAGVSTDSGIPDYRGPGGSLSKHRP---MTYQEFRHDPQASHRYWARSWRLMD
--QAAPNRSHFALVELEQQ-GHINGVITQNVDGLHAAAGTKNLLALHGDLATVMCLNCGFKEDRDGDVTLDQGCVKCGS-KLLKPDVVYFGEPPGRKKKI
RELLDAASAVVVVGSSLAVMSGYRIVIEAQRAGKPVAVINGGPGRADHRVEILWRTRVAPAFDDILDS-----------
>tr|M1NI84|M1NI84_9CORY NAD-dependent protein deacetylase OS=Corynebacterium halotolerans YIM 70093 = DSM 44683 GN=cobB PE=3 SV=1
-----------------------------------EQLNLGPALVVTGAGVSTDSGIPDYRGPRGSLSRHRP---MTYQEFSHDPAASHRYWARSWRQID
--VAGPNRTHFALVELERA-GFVHGVVTQNVDGLHREAGSENLVPLHGDLATVMCLDCGHREERDGDVTLPQGCAMCGS-ARLKPDVVYFGEPPVRKRRA
AQMLADSASLIVAGSSLAVMSGYRIALDACKQGKPVAVINGGPGRADGKVTTLWRTRVAPAFDALLDE-----------
>tr|A0A0G3GTG7|A0A0G3GTG7_9CORY NAD-dependent protein deacetylase, SIR2 family OS=Corynebacterium mustelae GN=cobB1 PE=4 SV=1
-----------------------------------HQLRSGGVLVLTGAGVSTDSGIPDYRGAQGSLKRHRP---MTYQEFRFDPQALKRYWARSWRYID
--RAQPNAVHGYIAEWERA-GQVVGVVTQNVDGLHQLAGSRNILPLHGDLATVICLDCGQREDRDGDVALAAPCANCGS-TVMKPDVVYFGESPRRKERL
QDLLVDASSVLVLGSSLAVMSGMRIVIDAKKQGKPVSIVNAGPSRADNRMDIVWRSLLRPACEKISEA-----------
>tr|D2NR35|D2NR35_ROTMD NAD-dependent protein deacetylase OS=Rothia mucilaginosa (strain DY-18) GN=RMDY18_02790 PE=4 SV=1
-----------------------------------KLLKAGKVLVLTGAGVSTESGIPDYRGPGGSLHDHRP---MTYQEFRYDDAARQRYWARSWRRMR
--RAEPNRAHYALAELEQL-GAVSGVITQNVDGLHARAGSSRLLALHGDLSRIVCLDCGQDESRDGDVELDDPCLGCGS-TRLKPDVVYFGESPARKALK
DAMLAECSALLVVGSSVAVMSSYKIVLEALRAGKPVAVINGGPGRADAKATYLWRTGVGEALELMLDE-----------
>tr|A0A099HCS9|A0A099HCS9_9MICC NAD-dependent protein deacetylase OS=Rothia dentocariosa GN=ES20_01880 PE=4 SV=1
-----------------------------------GMLRAGRVLALTGAGVSTESGIPDYRGPAGSLREHRP---MTYQEFRYDDAARQRYWARSWRRMK
--EAKPNRAHYALVELEQH-GAVSGVITQNVDGLHAQAGSRNILALHGDLSTIICLTCGHREGRDGDVELDNGCIACGS-QRLKPDVVYFGESPARKERL
RHMLADSTALLVVGSSVAVMSSYKIVLDTLRANKPVAVLNGGPGRADARATYLWRTNAGDALGQLLDR-----------
>tr|D8URW8|D8URW8_9MICC Transcriptional regulator, Sir2 family OS=Rothia dentocariosa M567 GN=HMPREF0734_01077 PE=4 SV=1
-----------------------------------KMLRTGGVLALTGAGVSTESGIPDYRGPSGSLLDHRP---MTYQEFRYDDAARQRYWARSWRRMR
--RASPNRAHYALAELEHA-GAVNGLITQNVDGLHVSAGSKNVLALHGDLSSILCLDCGTRESRDGDVELDNGCTVCGS-TKLKPDVVYFGESPARKARQ
QQMLADSSGVLVVGSSVAVMSSYKIVLDALRADKPVGVMNGGPGRADARVTYLWRTGVGEGLEELLDR-----------
>tr|A0A0F6R090|A0A0F6R090_9CORY NAD-dependent protein deacetylase, SIR2 family OS=Corynebacterium kutscheri GN=cobB1 PE=4 SV=1
-----------------------------------AQLREKSVLVLTGAGISTDSGIPDYRGPNGSLTRHRP---MTYQEFRHDKQALHRYWARAWRQMA
--QAQPNNGHLFLAELERA-GMIHAIITQNVDGLHTRAGSKNVVAIHGDMSLIVCLDCGQKETRDGDVYLSEGCTHCGS-LMLKPDVVYFGEPPSTKRKV
AQLLKQSSSVLVIGSSLAVMSGMRIIIDAQKQGKKVAVINGGPGRADTRADIVWRSSITAAFSQLKEE-----------
>tr|A0A068S6E2|A0A068S6E2_9FUNG Uncharacterized protein OS=Lichtheimia corymbifera JMRC:FSU:9682 GN=LCOR_08343.1 PE=4 SV=1
-----------------------------------DMLHKGRTVIMTGAGVSTDSGIPDYRGDGGTYVKHRP---ILYHELLSSELFRRRYWARGWPEMS
--KARPNSSHHIMARFLSD-GYINHLITQNVDNLHRAAQQDQVTELHGSLYQVECLDCKTVVPRDGDVELPEPCTTCAS-RRMKPRVVFFGENRKVTTAA
ETMVRASSAMLVVGSSLATYSAYRLVRMASELGIPVGILCKGQTRADALASWKIEMGCTTVLERVQER-----------
>tr|A0A0C7BI44|A0A0C7BI44_9FUNG Uncharacterized protein OS=Rhizopus microsporus GN=RMATCC62417_06636 PE=4 SV=1
-----------------------------------DLFYKGRILVITGAGLSTDSGIPDYRGDQGTYVRHRP---ILYHELLSSHLYRQRYWSRSWPKMS
--QALPNGSHHALALLMQS-PYIQNIITQNVDYLHTKAN-ERLLELHGTLYKVECMDCDAEYDRDGDVELPDPCTSCGS-QKMKPKVVFFGENKPITKRA
EQLVNDCSAVVIIGSSLATYSSYRLIRMAHQQNKPIGILTKGPTRADSLMAWKGEVGCTPVLVELSRR-----------
>tr|M2YC35|M2YC35_9MICC NAD-dependent protein deacetylase of SIR2 family OS=Kocuria palustris PEL GN=C884_00683 PE=4 SV=1
-----------------------------------EQLAGREALVISGAGMSTASGIPDYRGPDAQ--PRQP---MSFQEFTGSPERRAHYWSRNWRNLQ
--RAEPNAAHRSLARLEAA-GAVRAVITQNIDRLHERAGSRCVIDLHGRYDRVRCMACATLIPRDADAEVAYDCPVCG--GVVKPDVVFFGESDPDVAAA
WHQTELAQALLVLGTSLTVHSARRFVRRAVRAGIPVVIVNHGQTRSDADASVKIDAQVADFLAAAEAP-----------
>tr|A0A0J1BQA5|A0A0J1BQA5_9MICC NAD-dependent deacetylase OS=Kocuria sp. SM24M-10 GN=ABL57_16510 PE=4 SV=1
-----------------------------------PLLSGRRTAVLTGAGISTDSGIPDYRGPGSA--PRTP---MTFQEFMGSPARRSHYWARNWRHLE
--RADPNPGHGVLARLEGA-GAVAGVVTQNIDRLHQAAGSLNVVDLHGRFTRVLCMRCGTRIPRDADAVVPRDCPVCS--GILKPDVVFFGENPRRVLRA
LRMVDTADALLVVGSSLTVNSGRRFVRHAVRAGVPVLIVNHGRTRGDAAARVKVDAPATEFLVRLEQR-----------
>tr|A0A0M2CS69|A0A0M2CS69_9MICC NAD-dependent deacetylase OS=Kocuria sp. UCD-OTCP GN=H488_0113185 PE=4 SV=1
-----------------------------------ALLGGRRTAVLTGAGISTESGIPDYRGPGST--PRTP---MTFDEFMGSAAMRSHYWARNWRHLA
--RARPNAGHAALARLEEW-GSVTGVVTQNIDRLHQAAGSLNVVDLHGRYTQVGCMRCATRIPRDADAVVPRDCPVCG--GVLKPDVVFFGENPRRVLRA
LRMVDAADALLVVGSSLTVNSGRRFVRHAVRADVPVVIVNHGRTRGDAAARLKVDASATAFLVGLEQR-----------
>tr|A0A081HY74|A0A081HY74_9MYCO NAD-dependent protein deacetylase OS=Mycobacterium sp. TKK-01-0059 GN=cobB PE=3 SV=1
-----------------------------------TLLAGRRIAVLTGAGVSTDSGIPDYRGPDSP--PSNP---MTIQQFTGDAAFRQRYWARNWRHMA
--DTLPNAGHRALAALEDA-SVVTGVITQNVDLLHTKAGSRNVIDLHGTYARVICLSCGHTVSRDADAVVADDCVRCA--GMLNPDIVYFGDSPKVVAAA
YRMVDEADALLVAGSSLTVFSGYRFVRHAAALGIPVAIINRGSTRGDDLATVKVDGGCSELLALLADE-----------
>tr|V7KMA4|V7KMA4_MYCAV NAD-dependent protein deacetylase OS=Mycobacterium avium subsp. silvaticum ATCC 49884 GN=cobB PE=3 SV=1
-----------------------------------AVLAGRRIAVLTGAGISTDSGIPDYRGPESP--PSNP---MTIRQFTGDPAFRQRYWARNWRHMD
--DTLPNAGHRALAALEDA-AVVTGVITQNVDLLHTKAGSRNVIDLHGSYARVICLGCGDTTSRDADAVVAEDCARCA--GMLKPDIVYFGESPKVVAAA
YRLIDESDTLLVAGSSLTVFSGYRFVRHAAARGIPIAIVNRGDTRGDHLATVKVDGGCSELLALLADE-----------
>tr|J4TIJ1|J4TIJ1_9MYCO NAD-dependent protein deacetylase OS=Mycobacterium colombiense CECT 3035 GN=cobB PE=3 SV=1
-----------------------------------TLLAGRRITVLTGAGISTDSGIPDYRGPDAP--PSNP---MTIRQFTGDPGFRQRYWARNWRHMH
--DTLPNAGHRALAALEEA-SVVTGVITQNVDLLHTKAGSRNVINLHGTYAQVICLGCGATMTRDADAVVADDCERCG--GMLKPDIVYFGESPKVVAEA
YRWVERADALLVAGSSLTVFSGYRFVRHAATLGIPVAIVNRGGTRGDDLANVKVDGGCSELLALLADE-----------
>tr|I4BLL1|I4BLL1_MYCCN NAD-dependent protein deacetylase OS=Mycobacterium chubuense (strain NBB4) GN=cobB PE=3 SV=1
-----------------------------------ELLRGRRVAVLTGAGMSTDSGIPDYRGPDSP--PANP---MTIRQFTSDRVFRQRYWARNWRHMD
--QRRPNAGHRALAALERA-GVVTGLITQNVDLLHTKAGSRAVVNLHGTYVQVVCLDCGHTMSRDADAVVGDDCPACG--GMLKPDIVYFGENPKVVDLA
YSLIDDADALLVAGSSLTVYSGYRFVRHAAAQGKPIAIVNRGRTRGDDLATVKIDNGCSPMMALLADE-----------
>tr|L0IZF7|L0IZF7_MYCSM NAD-dependent protein deacetylase OS=Mycobacterium smegmatis JS623 GN=cobB PE=3 SV=1
-----------------------------------ALLDGRRVAVLTGAGMSTDSGIPDYRGPDSP--PSNL---MTIRQFTSDAAFRQRYWARNWQHMD
--ATLPNAGHRAVAELEHA-GVVSGVITQNVDLLHTKAGSRTVINLHGTYAQVICLDCGHTLSRDADAVIGDDCPACC--GMLKPDIVYFGENPKRVEHA
YSLVDGADALLVAGSSLTVYSGYRFVRHAAALGIPIAIINRGRTRGDDLATVKIDSGCSEMLALLADE-----------
>tr|A0A064CLT7|A0A064CLT7_9MYCO NAD-dependent protein deacetylase OS=Mycobacterium aromaticivorans JS19b1 = JCM 16368 GN=cobB PE=3 SV=1
-----------------------------------SLLAGRRVAVLTGAGISTDSGIPDYRGPDSP--PANP---MTIRQFTSSQAFRQRYWARNWRHMA
--QTMPNAGHRALAHLERA-GVVTGIITQNVDLLHTKAGSRNVINLHGTYAQVVCLDCGHTMSRDADAMVTDDCPSCG--GMLKPDIVYFGESHKVVAQA
YSLMDESDALLVAGSSLTVFSGYRFVRHAAALGMPIAIINRGATRGDALATVTVDSGCSPMLALLADE-----------
>tr|F1YI67|F1YI67_9ACTN NAD-dependent protein deacetylase OS=Gordonia neofelifaecis NRRL B-59395 GN=cobB PE=3 SV=1
-----------------------------------ELIAGRRVVALTGAGLSTPSGIPDYRSPDSP--TRQP---MTIDAFLSSPESRRRYWARNWRHMD
--AAAPNAAHRALRSLQDA-GVVTGVITQNVDMLHMKAGSSPVVDLHGSYGRVRCLDCGALVSRDADAALEDDCTVCG--GTLKPDIVYFGETEKVVETA
FALVDDADVLLVAGSSLTVMSGLRFVRRAAAAGKPIAIVNRGGTRGDDLATLKIDHRCEVILPTVARV-----------
>tr|L7LK46|L7LK46_9ACTN NAD-dependent protein deacetylase OS=Gordonia sihwensis NBRC 108236 GN=cobB PE=3 SV=1
-----------------------------------ELMDGRRAVALTGAGLSTPSGIPDYRSPDSP--VRRP---MTIEAFLSSPESRRRYWARNWRHMD
--AAAPNAAHRALRTLQDA-GVLSGVITQNVDMLHMKAGSRPVVDLHGSYGRVRCLGCGEQVSRDADAALEDDCERCG--GVLKPDIVYFGETGPVVAQA
FSLVDDADLLLVAGSSLTVMSGLRFVRRAVAAGKPVAIVNRGRTRGDDLATLKIDHRCEVILPAVADR-----------
>tr|A0A0N9NBW0|A0A0N9NBW0_9ACTN NAD-dependent deacetylase OS=Gordonia sp. QH-11 GN=ACH46_08310 PE=4 SV=1
-----------------------------------DHLAGRRVVALTGAGISTSSGIPDYRSPGSP--KRNP---MTIDAFLSSPESRRRYWARNWRHMD
--AAQPNAAHRALVSLQEQ-GVVTGVITQNVDMLHMKAGSHPVIDLHGSYGRVRCLDCGAVISRDADAALEVPCSNCG--GILKPDIVYFGETPKTVERA
FAMVDDADAILVAGSSLTVMSGLRFARRAAAADKPVFIVNRGGTRGDELAELKIDHRCEVILPTAASL-----------
>tr|A0A0D5A5P8|A0A0D5A5P8_9NOCA NAD-dependent protein deacetylase OS=Rhodococcus sp. B7740 GN=cobB PE=3 SV=1
-----------------------------------SLLEGRTVTVVSGAGMSTDSGIPDYRGPQSP--PRNP---MTFQQFIGDAEFRRHYWARNWRHMD
--AAVPNDGHRALARLERA-GVVTGIITQNVDMLHTKAGSRNVIDLHGVYARVRCLNCERLISRDADAIISSDCESCS--GILKPDIVYFGESPKRVAEA
YDLVDRSDALLVLGSSLTVMSGLRFVRHASKKSKPIVIVNRGTTRGDEFASLTVHAGCSEVATALADD-----------
>tr|A0A0D0LPE7|A0A0D0LPE7_9NOCA NAD-dependent protein deacetylase OS=Rhodococcus sp. MEB064 GN=cobB PE=3 SV=1
-----------------------------------DAMAGGRVVALTGAGMSTDSGIPDYRGPDSP--PRNP---MTFQQFIGDDDFRRHYWARNWRHMD
--ATRPNAGHRALAELERV-GTVSGIITQNVDMLHTKAGSRSVIDLHGVYGRVRCLDCDRLISRDADAIIESGCEVCG--GILKPDIVYFGESPKRVRSA
YDMVDAASALVVLGSSLTVMSGLRFVRHAWKNEIPVFIVNRGTTRGDEFAAEKIEAGCSEVLAAFL-------------
>tr|M3VCM1|M3VCM1_9ACTN NAD-dependent protein deacetylase OS=Gordonia paraffinivorans NBRC 108238 GN=cobB PE=3 SV=1
-----------------------------------DMLAGCRVAVLTGAGISTESGIPDYRSPGSP--PRTP---MTLEMFLSSPEFRRHYWARNWRHMD
--AARPNSAHLALTDLQRA-GRVSTVITQNVDMLHTKAGTRGVIELHGCYGRVRCLSCDWRISRDADATLTDDCPQCG--GILKPDIVYFGEAPKLVEQA
FSVVDDADALLVVGSSLTVMSGLRFARRAHRAGKPIVIVNRGHTRADELATLKIDHRAGVVLPELSRA-----------
>tr|D5UXL7|D5UXL7_TSUPD NAD-dependent protein deacetylase OS=Tsukamurella paurometabola (strain ATCC 8368 / DSM 20162 / JCM 10117 / NBRC 16120 / NCTC 1
-----------------------------------GLLRGRRIVALTGAGVSTASGIPDYRSPGAP--RRTP---MTLQQFLGSPEFRRRYWARNWRHMD
--SARPNAAHRGVAGLP----GITGVITQNVDLLHLKAGSRGVIDLHGNYARVRCLSCDATISRDADVVVEDDCGRCG--GILKPDIVYFGESPKRVAEA
FTAVDRADALLVLGTSLTVMSGLRFVRYAHKHGKPIVIVNRGRTRGDALADVTVDVDVATALTALAER-----------
>tr|W9DHR7|W9DHR7_9ACTN NAD-dependent protein deacetylase OS=Gordonia alkanivorans CGMCC 6845 GN=cobB PE=3 SV=1
-----------------------------------DILAGRRTAVLTGAGISTDSGIPDYRSPGSP--PRTP---MTLEMFLSSPEFRRHYWARNWRHMD
--AALPNPAHLALTGLQDQ-GRVSAVITQNVDMLHTKAGTRGVLELHGCYGRVRCLRCDWRISRDADAMLADDCPHCG--GILKPDIVYFGETPKLVEQS
FSAVDEADALLVVGSSLTVMSGLRFARRAHRAGKPLIIVNRGHTRADELASLKIDHRAGVVLPALANR-----------
>tr|J9SGQ0|J9SGQ0_9ACTN NAD-dependent protein deacetylase, SIR2 family OS=Gordonia sp. KTR9 GN=KTR9_1991 PE=4 SV=1
-----------------------------------DILAGRRVAVLTGAGISTDSGIPDYRSPGSP--PRTP---MTLEMFLSSADFRRHYWARNWRHMD
--ATVPNRAHLALTELQQR-GWISRVLTQNVDMLHTKAGTRGVIELHGCYGRVRCLNCDWRISRDADATLSDDCPNCG--GILKPDIVYFGETARVVDEA
FSAVDAADALVVVGSSLTVMSGLRFARRTHRAGKPLIIVNRGVTRADDIATLKIDHEAGFVLPALATF-----------
>tr|H0QZ38|H0QZ38_9ACTN NAD-dependent deacetylase OS=Gordonia effusa NBRC 100432 GN=cobB PE=4 SV=1
-----------------------------------EVIGTGRVVALTGAGISTPSGIPDYRSPNAP--PRRP---MTIEQFMSSPDFRRHYWARNWRHMD
--AAKPNDAHRALTELQRT-GRLVGVITQNVDMLHLKAGTRNVVELHGCYGRVRCMTCTWRTTRDADAVVSDDCPGCG--GILKPDITYFGENPKTVQQA
FSLLDSADSILVAGSSLTVQSGLRFVRQAHREGKSVIIVNRGATRGDEFATLKADHFCEEVLPRLCRK-----------
>tr|M3VB80|M3VB80_9ACTN NAD-dependent protein deacetylase OS=Gordonia malaquae NBRC 108250 GN=cobB PE=3 SV=1
-----------------------------------QILDGRRTVVLTGAGISTPSGIPDYRSPGSP--VRNP---MTIGQFLSSPDFRRHYWARNWRHMD
--AARPNSAHHAIARMQRD-GSMTGVITQNVDMLHLKAGSVPTLDLHGSYGRVICLDCGNLLSRDADAVLHDDCENCG--GVLKPDIVYFGETPRVTDRA
FAMVDAAEAMLVAGSSLTVMSGLRFVRHAAQSGIPVVIVNRGGTRGDRFATLKIDHRCEVILPSLTAT-----------
>tr|G7H105|G7H105_9ACTN NAD-dependent protein deacetylase OS=Gordonia araii NBRC 100433 GN=cobB PE=3 SV=1
-----------------------------------RFLDGRRTIALTGAGLSTPSGIPDYRSPGAP--PRTP---MTIQMFLSSPEYRRHYWARNWRHMD
--AARPNAAHHALTAMERS-GHIAGIITQNVDMLHVKAGSRRMLDLHGSYGRVVCLGCGRLVSRDADVVLEDDCEQCG--GILKPDIVYFGESRKIVASA
YAMIDDADALLVAGSSLTVMSGLRFVRHAAKNGKPVAILNRGATRGDSLAALKIDQRCETVLPAVAQI-----------
>tr|D0LAK2|D0LAK2_GORB4 NAD-dependent protein deacetylase OS=Gordonia bronchialis (strain ATCC 25592 / DSM 43247 / JCM 3198 / NCTC 10667) GN=cobB PE=3 
-----------------------------------RLLAGRRFVALTGAGISTESGIPDYRSPGAP--RRTP---MTLEMFLSSPEFRRHYWARNWRHMD
--ASVPNVAHHALTDLQRS-GHLSTVITQNVDMLHTKAGTRGVLELHGCYGRVRCLGCGWTTSRDADAVVSDDCPDCG--GILKPDIVYFGESPKIVTQA
FTLVDEADALLVVGSSLTVMSGLRFARHAARTGKPVIIVNRGATRADNIAALKIDHFASSVLPALVTA-----------
>tr|M0QKQ5|M0QKQ5_9ACTN NAD-dependent protein deacetylase OS=Gordonia soli NBRC 108243 GN=cobB PE=3 SV=1
-----------------------------------ALLGERRLVALTGAGISTDSGIPDYRSPGAP--VRTP---MTLEMFLSSPDFRRHYWARNWRHMD
--AARPNDAHRALTALQRE-GRLLSVITQNVDMLHTKAGTRRVNELHGCYGRVRCLSCDWRISRDADAILSDDCPDCG--GIVKPDIVYFGESPRRVAEA
YSMVEEAEALLVVGSSLSVMSGLRFVRHAHRIGTPVVIVNRGITRGDDRATLKVDHLAGVVLPMLADS-----------
>tr|V8CWT9|V8CWT9_9ACTN NAD-dependent protein deacetylase OS=Williamsia sp. D3 GN=cobB PE=3 SV=1
-----------------------------------QLLDGRRVLALTGAGMSTDSGIPDYRSPGTP--PRTP---MTIEMFLSSSDFRRHYWARNWRHMD
--AAVPNAGHRALAALERR-GTVSGVITQNVDMLHLKAGNRAVLELHGSYGRVRCLDCEHRVSRDADVVVEDDCPDCG--GILKPDIVYFGESPKVVQQG
YSMVDDADAVLVLGSSLTVMSGLRFVRHARRTGKPIAIVNRGHTRGDECATMKIDGSCSEVLTGWLES-----------
>tr|K6W4I6|K6W4I6_9ACTN NAD-dependent protein deacetylase OS=Gordonia rhizosphera NBRC 16068 GN=cobB PE=3 SV=1
-----------------------------------ALLAGRRLVALTGAGISTESGIPDYRSPGAP--ARTP---MTLEMFLSSPQFRRHYWARNWRHMD
--AARPNAAHEAITDLQQQ-GRLIGVITQNVDMLHTKAGTRRVLELHGCYGRVRCLACDWQISRDADATVDDDCPACG--GIVKPDIVYFGESPKTVQQA
FSMLDEADALLVVGSSLTVMSGLRFARHARRTDKTVVIVNRGATRADDLADLKIDHLASVVLTALADP-----------
>tr|L7LD31|L7LD31_9ACTN NAD-dependent protein deacetylase OS=Gordonia hirsuta DSM 44140 = NBRC 16056 GN=cobB PE=3 SV=1
-----------------------------------GFLSGRRTLALTGAGMSTPSGIPDYRSPGSA--PRTP---MTIQQFLSSPDFRRHYWARNWRHMD
--ASLPNPAHHALAGLEHD-GLLTGVLTQNVDMLHIKAGSRRVLDLHGSYGRVLCLDCGHRLSRDADAVLADGCPACG--GTLKPDIVYFGETAAVVARA
YAMVDDADAVLVVGSSLTVMSGLRFVRHAVKHGKPVVILNRGATRGDEFAAVKIDGRCEQILPAVRRQ-----------
>tr|A0A0L6WMB6|A0A0L6WMB6_9AGAR NAD-dependent deacetylase sirtuin-5 OS=Termitomyces sp. J132 GN=J132_08981 PE=4 SV=1
-----------------------------------ALTRAKNVLILSGAGLSAASGIATYRNADSLWNNFDPKKYATPEAFKKDPVDLWTFYHRRRSAYL
--LAKPNAAHYALATLAHPSTAQPIHVTQNVDALALRAGADSIIEMHGDIFVTRCTSCQHLQRSLADLTVLPKCGGDGCGGLLRPEVVWFGEMPPRSGEI
ARKMSGCDMLLVVGTSSIVRPAADYAAQVKKNGGTVAIFNLGRSNGDEDADFVFIGPCEETLPEVL-------------
>tr|L7HQX2|L7HQX2_MAGOY NAD-dependent deacetylase sirtuin-5 OS=Magnaporthe oryzae (strain Y34) GN=OOU_Y34scaffold00969g35 PE=4 SV=1
-------------------------------------AKSRNIVAIIGAGLSASSGLATFRGPGGLWQNQDVFVLASPAGFVNDPGLVWQFYSYRREEAL
--KAQPNKAHRALAELARKVPG-FTMLTQNVDNLSPRAGHDQLLELHGNLFDLKCWGCGYTLDSKIDRKDLPQCPKCKS-ELLRPGIVWFGESPEDTDAL
FQDEDPIDLCLVIGTSAKVWPAAGYVDEARDKGARVAVVNLYEDDGSKNRDWSFIGDAAEVIPLILKPVIGE-------
>tr|A0A0F9XRU0|A0A0F9XRU0_TRIHA Glycosyl hydrolase family 92 OS=Trichoderma harzianum GN=THAR02_00770 PE=4 SV=1
-------------------------------------KSSRRILALCGAGLSASSGLPTFRGAGGFWRNYDATQLATVRAFKMDAGIVWLFYSYRRHLAL
--KAEPNMGHRALAALARR-NMDFLCLTQNVDNLSQRAESSQLKCLHGSLYDIKCSN--ESCDWIQDMDEIPKCPQCKK-GIQRPGVVWFGEDLAMMMDI
SARAEPIDLMFVIGTSAQVYPAASYIDKARKRGARIVTINPEAEDEAEMYKIKAFGKAAEYLPILLEPVI---------
>tr|A0A0J6I1Y5|A0A0J6I1Y5_COCPO Sirtuin OS=Coccidioides posadasii RMSCC 3488 GN=CPAG_01658 PE=4 SV=1
----------------------------------------KRVMAVIGAGLSAASGLPTFRGVGGLWRRYSAVDLATPEAFNATPGLVWQFYGYRRHMAL
--LAKPNRAHYALAEFAKK-NPNFIALTQNVDGLSERAGHSQIQRLHGSLFTIKCANEGQALEWAPDISDLPPCPECST-GLLRPGVVWFGE-PLVEETI
NTWLKPVDLVLVIGTSARVFPAVSYIDRGRCKGARVAIINMDRTHLPKPGDWIFEGDASAIIPELLKEVSARLS-----
>tr|A0A0A1TWD3|A0A0A1TWD3_ENTIV NAD-dependent deacetylase, putative OS=Entamoeba invadens IP1 GN=EIN_309190 PE=4 SV=1
--------------------------------------RSQRVVVLTGAGISVSAGIPDFRSKGGMWTRYDPKVYANYNNFLAHPEMFWKMSTELRVATS
--NKQPTKAHFALERLQR-MGKLSSLITQNVDNLHQLSGVENVIELHGTGKICHCIQCDYIVPWI----DIPRCPVCG--ALIKLDVVLFGE-PLQSDNF
FTAASSADVFLVIGSSLEVMPANQLPRRAKMSSSTVAFINKSSTRYDDFTDYTLRGDSDVLVPKLVDYVAK--------
>tr|M3SAP0|M3SAP0_ENTHI NAD-dependent deacetylase 1, putative OS=Entamoeba histolytica HM-1:IMSS-B GN=EHI8A_156600 PE=4 SV=1
--------------------------------------RSKRLVVLTGAGISVSAGIPDFRSRNGMWKRYEPKVYASYENFVNKPEMFWKMCNELRNCTE
--GKKPTKAHFALRKLEE-IGKLEEIITQNVDNLHQLAGSRKVIELHGTGKICQCIKCGYLIPWI----DIPRCPKCG--GLIKLDVVLFGE-QLEKEKF
FEVASSSDVFLVIGSSLEVMPANALPRKAKMNSATVAYINKTTTRFDNYADYVIRGESDYLIPKIVEYVIE--------
>tr|W5PQX2|W5PQX2_SHEEP Uncharacterized protein OS=Ovis aries GN=SIRT4 PE=3 SV=1
---------------------------------------SKRLLVMTGAGISTESGIPDYRSEKGLYARTDRRPI-QHGDFVRSAPVRQRYWA--RNFVG
WSSHQPNPAHWALSNWER-LGKLHWLVTQNVDALHTKAGSQRLTELHGCMHRVLCLDCGEQTTWSADVTEVPSCSRCG--GPLKPDVVFFGDTPDKVDFV
HKRVNEADSLLVVGSSLQVYSGYRFILTAREKKLPIAILNIGPTRSDDLASLKLDSRCGELLP----------------
>tr|G3VZP1|G3VZP1_SARHA Uncharacterized protein OS=Sarcophilus harrisii GN=SIRT4 PE=3 SV=1
---------------------------------------SKRLLVMTGAGVSTESGIPDYRSEKGLYARTDRRPI-QHVDFVRSAKIRQRYWA--RNFVG
WSSHQPNAAHLTLSSWER-LGKLYWLVTQNVDALHTKAGSRRLTELHGCMHRVLCLHCGVQTTWEADVTEVPSCAKCG--GPLKPDVVFFGDTHDKVDFV
HMRVKEADAILVVGSSLQVYSGYKFILAAHEEKLPIAILNIGPTRSDQFACLKLDFRCAELLP----------------
>tr|H9G6I1|H9G6I1_ANOCA Uncharacterized protein OS=Anolis carolinensis GN=SIRT4 PE=3 SV=2
---------------------------------------AQRLFVLTGAGISTESGIPDYRSEGGLYARTDRRPV-QHAEFLRSAKARQRYWA--RNFVG
WSSHRPNDAHLALWRWEQ-AGKLHWLVTQNVDALHAKAGSRRLTELHGCTHRVLCLDCGDPTGWRADVSEVPACERCG---PSKPDVTFFVDSKETVDFV
YQRLAEADAVLVAGFLAQVYSAYKFALAARDRKQPMAIVNIGATRADGFATLKLSLRCGELLP----------------
>tr|S4R999|S4R999_PETMA Uncharacterized protein (Fragment) OS=Petromyzon marinus PE=3 SV=1
---------------------------------------SRRLFVLAGAGLSTESGIPDYRSEGGLYARTSRRPM-QHAEFARSAVARRRYWA--RNFTG
WSSRRPNAAHLALGRWEQ-QGRLHWLVTQNVDALHAKAGSRRITELHGCSHRVVCLDCKEVTGWQQDVSDVPPCRSCG--GPLKPEVTFFGDNRRTVDDV
YQRL-ESDTVLVAGSSLQVYSGYRFIRAAYEEKIPIAILNIGPTRADALAQLKVSSRCGDILP----------------
>tr|T2M2B7|T2M2B7_HYDVU NAD-dependent ADP-ribosyltransferase sirtuin-4 OS=Hydra vulgaris GN=SIRT4 PE=2 SV=1
---------------------------------------CSKVFVITGAGVSTESGIKDYRSDKGLYATSKQRPI-EYLEFLKNPNKRQKYWA--RNYLA
WSSFQPNVNHHFLSAMEK-HGNLHWLVTQNVDSLHLKAGSVRVTELHGSSARVVCLTCGNKINWRSDVSEMVDCHKCG--GILKPEIVFFGDNPTVKEFC
YKMLSECDGVLVIGSSLQVYSSFRFIIAAKEKRIPIAILNIGETRGDPYAYLKLPYRAGEVLP----------------
>tr|Q28CB4|Q28CB4_XENTR Sirtuin (Silent mating type information regulation 2 homolog) 4 OS=Xenopus tropicalis GN=sirt4 PE=2 SV=1
---------------------------------------SQRLFVMTGAGISTESGIPDYRSEGGLYSRTERRPI-QHSEFVQSQAARRRYWA--RNFVG
WSSHEPNSAHVNLCKWER-AGRLHWLVTQNVDALHTKAGQCRLSELHGCTHRVICLGCQTVTSWNEDVTDVPACTKCG--GILKPQVTFFGDTRGFVFSI
YEQMKQADAMLIVGSSLQVYSGYRFALNAKELHLPIAILNIGPTRADHLAKVKVSARCGDVLP----------------
>tr|K1R299|K1R299_CRAGI NAD-dependent ADP-ribosyltransferase sirtuin-4 OS=Crassostrea gigas GN=CGI_10016083 PE=4 SV=1
---------------------------------------GRNILVLTGAGISTESGIPDYRSQGGLYATSKSRPV-IYQDFVKSDRIRQRYWA--RNFIG
WSSVQPNISHSFLKKLED-FGKVCWLVTQNVDALHFKAGSSMVTELHGSTHRVACLRCDYKTSWRADISQTPHCPKCS--GPLKPEIIFFGDNKSTVEFV
FQKVQECDQVLVVGSSLEVYSGYRFVLRASEMKKPITLLNIGPTRADKLADLKIDAKCSDVLK----------------
>tr|F7A153|F7A153_ORNAN Uncharacterized protein OS=Ornithorhynchus anatinus GN=SIRT4 PE=3 SV=2
---------------------------------------ARKLLVVTGAGVSTESGIPDYRSEGGLYARTDRRPI-QHADFVRSAGVRQRYWA--RNFVG
WSAHRPNSAHLALSNWER-RGKLYWLVTQNVDALHTKAGNRRLTELHGCMHRVLCLGCGEQTGWTADVAEVAPCGRCG--GPLKPDVVFFGDTRHKVDLV
HERVREADAVLVVGSSLQVYSGYRFILAAHEKKLPIAILNIGPTRSDKLATLKLSSRCGELLP----------------
>tr|C3YDA2|C3YDA2_BRAFL Putative uncharacterized protein OS=Branchiostoma floridae GN=BRAFLDRAFT_77952 PE=4 SV=1
---------------------------------------SKRLLVITGAGLSTESGLPDYRSVKPPRAGKDRGPV-MYQDFVKDTHVRQGNWA--RNYVG
WSSHRPNVSHRALVQWER-QGKLHWLVTQNVDDLHRKAGSERMTELHGSAFRAACLSCKHVVHWEADVTPAPHCGKCG--GPLKPDMVYFGECKDTVQLV
FEKLEESDSILVAGSSLQVYSAYRFVSAAHKQNKPVAILNIGPTRADNLAALKINSRCGDVLT----------------
>tr|A0A091D0T8|A0A091D0T8_FUKDA NAD-dependent ADP-ribosyltransferase sirtuin-4 OS=Fukomys damarensis GN=H920_14979 PE=3 SV=1
---------------------------------------SKKLLVMTGAGISTESGIPDYRSEKGLYARTARRPI-QHSDFVRSAPIRQRYWA--RNFVG
WSSHQPNPAHWALSTWER-LRKLHWLVTQNVDALHTKAGSQRLTELHGCMHRVLCLGCGEQTTWGADVSDVPSCLRCG--GPLKPDVVFFGDTPAKVDFV
HKLVKDADALLVVGSSLKVYSGYRFILTARDQKIPIAILNIGPTRSDDLACLKLSARCGELLP----------------
>tr|A0A0A1U512|A0A0A1U512_ENTIV NAD-dependent deacetylase, putative OS=Entamoeba invadens IP1 GN=EIN_389850 PE=4 SV=1
----------------------------------KAMEKAKSVTVLTGAGISVQSGIPDFRSSNGLWKRYDPAVYGTLDTFKTRPELFWSMA----EEIH
KIDAKPNDVHKELALLEK-MGVVKNIITQNVDGLHQMAGSKNVMEIHGNTRTCYCVCCGYITTWEKTEHPVPKCPKCG--GLMKLDVILFGEKLITYQSV
TKALENTDFLLVIGTSLKVAPCNIIPKSAKQNGAQVAFINCTTTMMDEYADYVVRGDLTEIIPQIAS------------
>tr|M3TES5|M3TES5_ENTHI Sir2 family transcriptional regulator, putative OS=Entamoeba histolytica HM-1:IMSS-B GN=EHI8A_109260 PE=4 SV=1
----------------------------------RSMEKSKNVTVLTGAGISVESGIPDFRSSNGLWKRYDPSVYGSYSNFKKHPELFWKMT----EEIH
KITAYPNHVHEALAELEK-IGVVKTIVTQNVDGLHQQAGSKNVVEMHGSGRACYCIDCDYISRWSKPVPPIPRCPKCG--GLLKLDVVLFGEKLVTYDEV
VEASTKTDFLLVIGTSLQVAPCNIIPFRAKHCGAQVAFINCSKTPMDEYADFVVRGDLKEIVPKIAN------------
>tr|I7M420|I7M420_TETTS SIR2 family transcriptional regulator OS=Tetrahymena thermophila (strain SB210) GN=TTHERM_00242580 PE=4 SV=2
-------------------------------------QKSKNAVILTGAGVSTASGIPDYRSGPGKWELEE-------NKKKFLEEKG-----KPQI-IL
AINAFPSPTHMAISKLYKE-NLIKSVITQNVDNLHHQSGIPDIHELHGNIISERCEKCNYVHYRYTPHNTGRICQGCD--GQLHDTLVFFGESLNIKQSA
QEQIESADLCIVVGTSLTVQSAARLVWISQQRGIPIVIINLQKTSYDS----------ALKINGLCEPIFDLI------
>tr|J9G2T7|J9G2T7_9SPIT Transcriptional regulator, Sir2 family protein OS=Oxytricha trifallax GN=OXYTRI_17562 PE=4 SV=1
-------------------------------------SQSKSFICFTGAGLSTSTGIPDYRSTAGAYELEI-------SEEDKK-SKT------RQIRSQ
VQRAKPSISHMALHALMEN-GYLKHLISQNTDGLHLKSGIPNLTELHGNTTVEYCKSCSKIYFRRCHHLTGRQCEKCG--GELADEIVHFGESPDKLVEA
LTAASQSDLCLTMGTSLRVKPANQIPIQTIKNKGQLAIVNLQYTPFDE---------AQIRMHSFTDQVLEIV------
>tr|A0A078B8N2|A0A078B8N2_STYLE Transcriptional sir2 family protein OS=Stylonychia lemnae GN=Contig12516.g13356 PE=4 SV=1
-------------------------------------ANSKNFTCFTGAGLSTSTGIPDYRSTAGQYELPP-------ETTDQQKIVF-----LNETRRQ
VQAAKPSLSHMALFALMQN-GYLKHVISQNTDALHLKSGIPNLTELHGNTTIEYCKSCSKMYFRRCNHITGRKCETCD--GDLADEIVHFGESPDKLVEA
LTVAQQSDLQLCMGTSLRVKPANQIPIQTLKNKGSIAIVNLQYTPFDE---------AHIRIHSLTDQVLVSA------
>tr|C1GFX8|C1GFX8_PARBD Cation-transporting ATPase OS=Paracoccidioides brasiliensis (strain Pb18) GN=PADG_06164 PE=3 SV=2
-------------------------------------KSSERVLVVLGAGLSAASGIGTYVDEGGYWRTHNVRRLGTYGAFREDPSLIWWFYSDRRREMM
Q--AEPNKGHYAIAELAKKMGNRMLTVCQNIDGLCPRAGQPTTVYLHGDYFTFKCSSEKCTYTRRDELVSLPRCPACS--SLLRPSVTWFGEMPSTVNRI
DDWLDQIDLVLLIGTAATVHPVLSLVVETRKKGAKVCVVNPDKTSAEGGLDEGNWGGAEEVLTEIFKGVIGAL------
>tr|M1V8L2|M1V8L2_CYAME NAD-dependent deacetylase sirtuin 2 OS=Cyanidioschyzon merolae GN=CYME_CML119C PE=4 SV=1
------------------------------------RDRTPRVLVILGAGVSTAAGIPDFRSTTGLYARLETKGQLDASRFRTQPQ---AFYSLAHELLR
GGCLQPTRAHWFVRCLAER-GYLVRCYTQNVDGLERLAGISLLVEAHGTMQRAHCTACGAAYDAKLQVVSPPRCSRCQ-AGYVKLAIIFFGELPWRVFRL
MTDLWRCNLCLIMGTSLTVAPVRWI-PEQLPKRTPRILLNRSPSGSRRPLDLWIADDAQHSVERLVDLC----------
>tr|A0A0F8C0J3|A0A0F8C0J3_LARCR NAD-dependent deacetylase sirtuin-3, mitochondrial (Fragment) OS=Larimichthys crocea GN=EH28_04334 PE=4 SV=1
------------------------------------EQQYKRVVVMAGAGISTPSGIPDFRSGSGLYDNLQQYNLPYAEAFHHNPN---PFFALAKELYP
-GNYQPNVTHYFVRLLHKK-GQLLRMYTQNIDGLERLAGIEMLVEAHGTFATATCTVCQRKYEGEEDVMSVPKCPTCK--GVVKPDIVFFGELPRHFFKY
LIDFPAADLLIVMGTSLEVEPFASL-AGAVRSSVPRLLINRDLVGPWRPQDVVQLGDVVSGVQALVDAL----------
>tr|A0A0P7XRI7|A0A0P7XRI7_9TELE NAD-dependent protein deacetylase sirtuin-3, mitochondrial-like (Fragment) OS=Scleropages formosus GN=Z043_102536 PE=4 SV=1
------------------------------------EGEYKKVVVMVGAGISTPSGIPDFRSGSGLYDNLQQYKLPYAEAFHYNPQ---PFFALAKELYP
-GNYQPNLTHYFIRLLYDK-GQLLRLYTQNIDGLERRAGISKLVEAHGTFATATCTVCRKEYPGEDDIMAIPKCSTCK--GIIKPDIVFFGELPQQFLMY
LTDFPMADLLIIMGTSLEVEPFASL-AGAVRGSVPRLLFNRDAVGPHRHNDVAELGDVVSGVQKLVDAM----------
>tr|H3AAK5|H3AAK5_LATCH Uncharacterized protein OS=Latimeria chalumnae GN=SIRT3 PE=4 SV=1
------------------------------------NRECNRIVVMAGAGISTPSGIPDFRSGSGLYDNLRHFGIPYPEAFLHDPK---PFYSLAKELYP
-GNYKPNWAHYFVRLLYKK-GMLLRMYTQNIDGLERLAGISMLVEAHGSFATASCTVCCESYPGENEVMEVPLCPICT--GVIKPDIIFFGQLPKRFFLY
LTDFPLADLLIIMGTSHEVEPFASL-AGAVRSSVTRLLINRDLVGPWRSNDVVELGEVIGGVRKFVDLL----------
>tr|G3PT13|G3PT13_GASAC Uncharacterized protein OS=Gasterosteus aculeatus PE=4 SV=1
------------------------------------ERRYAKVVVMAGAGISTASGIPDFRSGSGLYDNLQQYDLPYAEAFHHNPR---PFFALAKELYP
-GNYRPNVTHYFVRLLHEK-SQLLRMYTQNIDGLERLAGIEMLVEAHGTFATATCTVCLREHQGEEDVMSVPQCPTCR--GVVKPDIVFFGELPRHFFKY
LTDFPRADLLVVMGTSLEVEPFASL-AGAVGGSVPRLLINRDPVGPGRARDVVRLGDVVEGVRALVDAL----------
>tr|A1L2B7|A1L2B7_DANRE Sirtuin (Silent mating type information regulation 2 homolog) 3 (S. cerevisiae) OS=Danio rerio GN=sirt3 PE=2 SV=1
------------------------------------ERKFKRIVVMAGAGISTPSGIPDFRSGSGLYDNLQQYNLPYAEAFHHNPN---PFFALAKELYP
-GNYQPNLTHYFIRMLHDK-EQLLRMYTQNIDGLERMAGIKMLVEAHGTFATATCTVCRRDYKGEEDIMAVPKCPTCK--GIIKPDIVFFGELPQHFFTY
LTDFPIADLLIVMGTSLEVEPFASL-AGAVRGSVPRLLINRDLVGPSRHTDVAELGDVVNGVKKLVELL----------
>tr|V9KQZ1|V9KQZ1_CALMI Sirtuin 3 OS=Callorhinchus milii PE=2 SV=1
------------------------------------NKECQRIVVMAGAGISTASGIPDFRSGSGLYDNLQTYDIPYPEAFHCNPK---PFFVLAKELYP
-GSCWPNFTHYFVRLLHQK-GILLRMYTQNIDGLERMAGIEKLVEAHGTFATATCTVCLKAYSWEEDVMQVPQCATCS--GVIKPDIVFFGELPQKFDLH
MLDLPLADLLVIMGTSLEVEPFASL-SGMVRGSVPRVLINQDLVGSRRGGDVTELGDIVRGVERFAELL----------
>tr|F9X1B3|F9X1B3_ZYMTI Uncharacterized protein OS=Zymoseptoria tritici (strain CBS 115943 / IPO323) GN=MYCGRDRAFT_98741 PE=4 SV=1
-------------------------------------QRSNKIMVITGAGISTSLGIPDFRSHTGFYSKLADIGYSEPEEFDEDPS---IFYGLAGDILP
-DHQRISPTHAFIRLLQDN-NRLQTNFTQNIDNLEALAGISRLIQCHGSFATASCRKCKHQVPGTDDIRAVPIYDIPT-PGVLKPDITFFGELPDVFFTF
TIDAPTTDLVLILGTSLQVAPVSDM-PNFLPHGVPHVYVSRERLRH-VAVDVQLLGDCDVVVGELCKRL----------
>tr|A0A0R3SFH6|A0A0R3SFH6_HYMDI Uncharacterized protein OS=Hymenolepis diminuta PE=4 SV=1
-------------------------------------KMRSKIMVLTGAGISVSCGIPDFRSSGGIYARLKRPQLSCPEDFKSDPR---PFYSFAKDIFP
-GQFRPSLTHQFIRSLERK-SKLLQNYTQNIDTLEQVAGISKVCYCHGSFATASCMDCRRSFSGEDAVMSIPYCPHCNPTGVVKPDIVFFKELPSHFTDC
IMDRNETDLLLVIGTSLQVYPVASI-PRYLPVNIPKVLINREPIDD-LKFDFELIGDCDVIVRHLCSEL----------
>tr|A0A0P5I244|A0A0P5I244_9CRUS Putative NAD-dependent protein deacetylase sirtuin-1 OS=Daphnia magna PE=4 SV=1
-------------------------------------RSCKKILVLTGAGVSVSCGIPDFRSRDGIYARLAVPDLPDPQAFRKDPR---PFFKFARDLWP
-GQFTPSKCHKFIRLLERQ-NKLLRNYTQNIDTLEQQADIERVIQCHGSFATATCLRCQHRVPSNEDIMEIPLCPKCLNQPIMKPDIVFFGEMPDEFHQA
MLDKEECDLIIVIGSSLKVRPVALI-PCALPNHVPQILINREPLRH-MVFDVELLGDCDIIVNQLCHLW----------
>tr|A0A0L0D7S5|A0A0L0D7S5_THETB NAD-dependent deacetylase sirtuin-6 OS=Thecamonas trahens ATCC 50062 GN=AMSG_04487 PE=4 SV=1
-------------------------------------DAQGKAVVLTGAGVSTGPGAALYRGPDGVWTRR-IRNSLKLEEGSESDATAADDDDG-SGIAG
EHKPQPTLTHRGLTALVDA-GLIGCVATTNVDGLHAAAGGSNYAELHGSLYVEACSACGAELCHNPLVATGTSCKACG--GAMEATLVGFFDHQSSMEQQ
FELAATADLMIVLGSSLSVET--TLPGYTLENGGRLVIVNLQPTH--------LDDQATLVVHARSDD-----------
>tr|S9U767|S9U767_9TRYP NAD dependent deacetylase OS=Angomonas deanei GN=AGDE_01242 PE=3 SV=1
-------------------------------------VGGKGVVFLTGAGCSTESGIPDYRGPQGTYRRA-DFVPLTFQKFMQNDY-EKKRYWL-RSMLG
MTGASCNPAHTGLHALQQS-GVVSHIITQNVDGLHHLATEANLTELHGNIHLVLCMGCHRVLPRDHLQVRLVHCQHCG--GYLKPHVVLFGEVSKVVTST
VEV--GASCLVCMGTSLQVFSAYRYVLAAREAGVPVVIVNSGKTR--------ADGMESLRIHTDSVA-----------
>tr|A0A0K2SN52|A0A0K2SN52_9FIRM NAD-dependent deacetylase OS=Limnochorda pilosa GN=LIP_2403 PE=4 SV=1
-------------------------------------LGRGGVAVLTGAGCSTESGIPDYRSSQGLWKRH-PQELGTPHGMEA----WPEEFYA-FYAAR
LQEARPNQAHLALARFQQA-GLLAALITQNVDGLHQAAGAQDVIELHGSMAHTRCQRCGRKDRPERLLHDRPACRHCG--GPLRPDVVLFGELPEAAERA
FRA--SCRLFLVVGSSLQVAPAASLPGQALLAGAPLAVVNLDPTP--------YDDQARWLLR-EPAG-----------
>tr|S9TTB1|S9TTB1_9TRYP NAD dependent deacetylase OS=Strigomonas culicis GN=STCU_09303 PE=4 SV=1
-------------------------------------VGKRNVVVLTGAGCSTESGIPDYRGPHGKYRRP-DFVPLTFQAFNSNDY-QKKRYWA-RSMLG
MSGASCNATHMGLCALERA-GVVQHILTQNVDGLHHLATDARLIELHGNIHLVICMLCKHILSREHLQMRLVYCPCCG--GHLKPHVVLFGEVSTTVTVS
MDL--QSSCLLCLGTSLQVYSAYRYVLAVKGEGCPRCHCQFWQDP--------RRWGESLKIDTASVA-----------
>sp|Q57YZ9|SIR4_TRYB2 NAD-dependent protein deacylase SIR2rp2 OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) GN=SIR2rp2 PE=3 SV=1
--------------------------------------GLQRCVILTGAGCSTESGVPDYRGPNGLYRRP-NFVPLTRQVFLSGSE-HRKRYWA-RSMFG
VSGASCNDTHMGLYELYRA-GVVNRLLTQNVDGLHHLAANSGVLELHGNIHQVCCMQCGDVSPRRRLQMQLVCCEHCG--GLLKPHVVLFGEVPKCVREA
YTA--AASCLICLGTSLQVFSALRFVLAARESGVPIAIVTAGRTR--------ADGLEELKVDTNSTA-----------
>tr|G0U0Q0|G0U0Q0_TRYVY Putative transcriptional regulator/Sir2 family protein OS=Trypanosoma vivax (strain Y486) GN=TVY486_0802580 PE=3 SV=1
--------------------------------------GARRCVVLTGAGCSTESGIPDYRGPNGLYRRA-NFVPLTLQAFIKKER-EQKRYWA-RSMLG
MSGASCNAAHLGLFDLCRA-GVVEHLLTQNVDGLHHLAANYGVQELHGNIHQVCCMKCGDITSRQQLQMQLVQCERCG--GALKPHVVLFGELPPRVETA
TAA--GASCLLCVGTSLQVFSAYRHVLTARECCVPVAIVTAGVTR--------ADGLESMRVETNSVA-----------
>tr|A0A088RRR1|A0A088RRR1_9TRYP Sir2-family protein-like protein OS=Leishmania panamensis GN=LPMP_231350 PE=3 SV=1
-------------------------------------KPGRSCVVLTGAGCSTESGIPDYRGPNGRYHRA-DFVPLTFQKFMGDDN-EKRRYWA-RSMLG
MSGASCNATHMVLQAFTKS-GAVSYILTQNVDGLHHLAMDAPLTEVHGNIHNVICTSCGFLMPRARLQMQLVMCPQCD--GFFKPHVVLFGEVPKIVEST
MSV-DKASCLLCLGTSLQVYSAYRYVLEAKQLGIPVAIVNSGTTR--------GDPIADLRLNVESVG-----------
>tr|E9AWD9|E9AWD9_LEIMU Sir2-family protein-like protein OS=Leishmania mexicana (strain MHOM/GT/2001/U1103) GN=LMXM_23_1210 PE=3 SV=1
-------------------------------------KPGRGCVVLTGAGCSTESGIPDYRGPNGQYHRT-DFVLLTFQSFMRDDN-EKRRYWG-RSMLG
MSGASCNAAHMALHAFTKS-GAVAHILTQNVDGLHHLATDAPLKEVHGNIHNVICTSCGFLMPRARLQMHLVMCPRCN--GFLKPHVVLFGEVAKIVETT
MSV-DKASCLLCLGTSLQVYSAYRYVLEAKQLGIPVAIVNAGATR--------ADAIADLKLNVESVG-----------
>tr|A0A0N0P4H7|A0A0N0P4H7_LEPSE Sir2-family protein-like protein OS=Leptomonas seymouri GN=ABL78_5621 PE=3 SV=1
-------------------------------------MADRSCVVLTGAGCSTESGIPDYRGPHGRYHRP-DFEPLMFQNFCRDDN-EKRRYWA-RSMLG
MSGASCNAAHMALQAFTTS-GTVAHILSQNVDGLHHLATNAPLTEIHGNIHNVICVSCGFIAPRAQIQMRLVHCPHCG--GFFKPNVVLFGEVPKTLEAT
MKL-DKASCLLCLGTSLQVYSAYRYVVEAKRLNIPVAVVNAGKTR--------ADPVADLKLDVESVG-----------
>tr|A0A0N0VGR5|A0A0N0VGR5_9TRYP Sir2-family protein-like protein OS=Leptomonas pyrrhocoris GN=ABB37_02063 PE=3 SV=1
-------------------------------------KAERSCVVLTGAGCSTESGIPDYRGPHGRYHRA-DFVPLTFQNFKRDDN-EKRRYWA-RSMLG
MSAASCNATHMALQAFVNA-GAVAHILTQNVDGLHHLATNAPLTEIHGNIHTVICMSCGFIMPRAQLQMRLVMCPHCG--GFFKPHVVLFGEVPKTVEVT
MQV-TKASCLLCLGTSLQVYSAYRYVVEAKRLNVPVAVVNAGKTR--------ADPVADLKLDVESVG-----------
>tr|G0URT3|G0URT3_TRYCI Putative NAD dependent deacetylase OS=Trypanosoma congolense (strain IL3000) GN=TCIL3000_8_3140 PE=3 SV=1
--------------------------------------GSRRCVVLTGAGCSTESGLPDYRGPSGLYRRA-NFTPLTWRAFLSSSD-NQKRYWA-RSMFG
VSGVSCNATHVGLYRLCRA-GVVGQLLTQNIDGLHHLAYDYGVIELHGNIHNVCCLKCGNVSSRQLLQMQLVFCEHCG--GLLKPHVVLFGEVPSRVTVA
ISA--EASSLICLGTSLQVFSGYRFVLAARESSVPVAIVTSGKTR--------ADGLEDLRIDTHSTA-----------
>tr|A0A0B2UL97|A0A0B2UL97_9MICR Sirtuin-like protein OS=Ordospora colligata OC4 GN=M896_031250 PE=4 SV=1
-----------------------------------KTFAQKRVVVLTGAGISVSCGIPDFRSQKGIFNDIKKTLISGRNGISVAKETRNIYIKYLKNMVD
--LATPSLTHRFLLSYS-EISKGFRLYTQNIDGLEEKAGMAPLVYLHGNMKELACLYCGARLNFGETAGNEITCACCILVGMMHTTIIHYDQ-QHFISKM
AQNDGCCDLFIVMGTSLRVLGVKKLARYLEGTKGRRILVNLETKEFVDLFDFFWNGD----CDEFCEIVGECIGINT--
>tr|S7WAX0|S7WAX0_SPRLO SIR2-like protein OS=Spraguea lophii (strain 42_110) GN=SLOPH_1886 PE=4 SV=1
-----------------------------------DSFYHKKVVIILGAGVSTASGIPDFRSSSGIFSHIQTRYVKGERRFSLNPETRNIYLDFLKDLVD
--KSEPSLTHKFLNEYT-NKCRKFRIYTQNVDLLEEKAGIKHLVYLHGDLNTLKCLYCGYKMAFTQKQEQEIECDKCLEQGIMHPNIVHYNQ-PHHISKL
NTLDSRCDLVLVIGTSLKIFGLKAMTKYCKENGGKSIYIDLVEKEFKNLFDYMYKGP----CDEFFRKIADTEILDK--
>tr|I3EP56|I3EP56_NEMP1 Uncharacterized protein OS=Nematocida parisii (strain ERTm1 / ATCC PRA-289) GN=NEPG_01236 PE=4 SV=1
-----------------------------------SLLRKTKASFITGAGISTSAGIPDFRSENGLFKEIKKKYYSGEDSIVSNPELMNIYLELLKQSLE
--QIDPTPTHKMLE-YV-QRKYKSTIYTQNIDGLERKAGIIQVHYLHGSLDKLLCTYCQHKTDYT--LVKKEECFMCIEIGILMPDIVLYGG-PHTAASV
I-QEKNTSLLIVMGTSLKVYGVKNLLKTVKGNEGIRVYVGIEPKPMQVYFDYWIEGK----CDTFSELLMDAINGPL--
>tr|A0A086J021|A0A086J021_9MICR Uncharacterized protein OS=Nematocida sp. 1 ERTm6 GN=NESG_02264 PE=4 SV=1
-----------------------------------SLLRKTKTSFITGAGISTSAGIPDFRSENGLFKEIKKKYYSGEDSIVGNEQAMEIYIDLLKTALA
--TVLPTPTHKMLT-HV-QRMHKSTIYTQNIDGLEQKAGISEIHYLHGSLENLLCTHCHHCTPYI--LAKRIKCTVCVKIGTLLPDIVLYGG-PHTAEAV
T-KEKDTSLLIVMGTSLKVYGVKNLLKTVKTNQGIRVYVGIEPKPMQIYFDYWIEGK----CDVFSDLLMDAIHGPM--
>tr|A0A066V905|A0A066V905_9HOMO Uncharacterized protein (Fragment) OS=Rhizoctonia solani AG-8 WAC10335 GN=RSAG8_10627 PE=4 SV=1
-----------------------------------ALEAASQV-------------TIDFRSADGLYSRARSEMLRGSEQVFRDPQKLIAYGRALRTTSR
--NATPTPCHDYIATLH-GLGRLLRCYTQNIDGLQTRG----VLELHGNIQRLRCNRCSQSPDECEQVDGYVHCNKCQQPGLLLPQVLHNEGSPQSLDEL
ERADGLASLLLVVGTSIKTDGAARLVKSVHAGGGVVVYIDRAPRKWGDFFDLQLQTE----IDSWARDASGCLNALD--
>tr|A0A0B7F540|A0A0B7F540_THACB NAD-dependent histone deacetylase HST3 OS=Saccharomyces cerevisiae (Strain ATCC 204508 / S288c) GN=HST3 PE=1 SV=1 OS=Thanatepho
-----------------------------------ACGAASHVVVVCGAGISTNAGIPDFRSADGLYNKALPGLTLGPERVLQDREKLLSYGRALRIASK
--RTSPTVCHNYIAKLH-EHGRLLHCYTQNVDGLQTSN----VLELHGNIHQVQCNQCGQSPDEDPNKDGYVRCEKCGKPGLLLPKVLHNEGSIELMDEL
EQMDSVASLLYILGTSIRTDGAAKLIRAVHNNNGIVVYVDRQARKLASYFDLQIQSD----LDVWAKDACQSLNNVS--
>tr|A0A074RPX0|A0A074RPX0_9HOMO SIR2 family transcriptional regulator (Fragment) OS=Rhizoctonia solani 123E GN=V565_107940 PE=4 SV=1
-----------------------------------VMACAQQVTVVCGAGISTKAGLRDFRSPDGIYNAPLGDGILGSESTLRDPQKLREFSRIMRIQAR
--QAALPDCHKWIAELY-RLGRLVRCYTQNVDGLQTRD----VVELHGTNVYLRCHKCRQRPREPPSEDGSATCTLCSIPGILLPEVLLNEDSPSTLEAM
KEDDSHCDLLLVLGTSLRSHGAASLVRDVHAQGGMVIYINLTSSSWSSYVDLHIRVD----VEEWASENLAQLHHG---
>tr|A0A066VH77|A0A066VH77_9HOMO Uncharacterized protein (Fragment) OS=Rhizoctonia solani AG-8 WAC10335 GN=RSAG8_09715 PE=4 SV=1
-------------------------------------------MVVCGAGISTHAGIPDFRSENGIRNRTFGDRLRGSERTLLDHEKRKVFNQEMRMACR
--QTKPTTCHALIARLY-DNKQLVRCYTQNIDGLQTRD----VFELHGTNMHVKCGVCNRRPTQSPGSNGYAACPTCLSPGELFPDVLLNDQALWPIDQL
VRQDAQCHMLLIIGTRLKSKGAANLVKAVRQSGGVVVYVDWYASSWARYVDLHIQMD----LEVFAKGYLDALDSV---
>tr|A0A074RE61|A0A074RE61_9HOMO Sir2 family transcriptional regulator (Fragment) OS=Rhizoctonia solani 123E GN=V565_320090 PE=4 SV=1
-----------------------------------VLAPALRVTVVCGAGISTYAGIPDFRSDQGLYTKAFGQDLLGSERTLRDPTKLIAYNQAMRILAR
--GAVPTSCHRYIEALS-KFGRLLRCYTQNIDGLQTRD----VVELHGTNVYLRCHKCGKRPQEPTTQDGYAECPQCITPGALLPDVLLNEGSPTTLGEM
MDDDSNCDLLLIIGTSLRSTGAAGLVKGVHTHGGVVVYVNLTASVWSNYIDLHIEVE----IEEWARD-----------
>tr|A0A066VAK0|A0A066VAK0_9HOMO Uncharacterized protein (Fragment) OS=Rhizoctonia solani AG-8 WAC10335 GN=RSAG8_11420 PE=4 SV=1
-----------------------------------ILASASATTVVCGAGISTSAGIPDFRSEDGLYSLGIKDLRKPSEQILQDPDTLRAFGRA------
---------------LH-DKGRLLRCFTQNIDGLQTRE----VVELHGSNVHLMCHKCHRRPEQDIERDGVIECSRCNEPGYLLPRVLYNQDSLENLDQL
ERAAGCADLLLVIGTSLSIDGPIKLVQSVHQVGGAVVYIGKGSSKWCTYFDLHIETD----IDTWIYEASRYLAVVS--
>tr|A0A0D4E8N9|A0A0D4E8N9_YEASX Hst3p OS=Saccharomyces cerevisiae YJM244 GN=HST3 PE=4 SV=1
------------------------------------LSRSRRIACLTGAGISCNAGIPDFRSSDGLYDLVKKDCKSGREMLFRDDFKISIFAKFMERSN-
VQLAKPTKTHKFIAHLKDR-NKLLRCYTQNIDGLEESIGLTDVVQLHGDLKTLSCTKCFQTFPWSRYWSRLPLCPDCEAVGILRPNIVLYGENHPSCEII
TQGLNNPDFLIIMGTSLKVDGVKQLVKKLHDRGGLIILVNKTSSSWHGIIDYQIHSD----------------------
>tr|A0A0C9ML99|A0A0C9ML99_9FUNG DHS-like NAD/FAD-binding domain-containing protein OS=Mucor ambiguus GN=MAM1_0727c11158 PE=4 SV=1
------------------------------------IAKSKRALVVTGAGISCSSGIPDFRSADGLYNIVKQRHLRGKELLFRNEKTIKCFYTFMAESL-
ITSANPTATHEFIQSMTNK-GQLLRCYTQNIDFLEENLNIP-AIQLHGTMKQVRCTLCSATYDFTDDYESAPACPQCED-GTLRPAIVLYNEEHPQGESI
GQLQVKPDLMIVMGTSLKIPALKKFIKQAHSPGGCVVFVNRTSKEWEKVFDYEVLGD----------------------
>tr|A0A0C9LU85|A0A0C9LU85_9FUNG DHS-like NAD/FAD-binding domain-containing protein OS=Mucor ambiguus GN=MAM1_0068d04046 PE=4 SV=1
------------------------------------IDNSKRVLVITGAGISCSGGIPDFRSSDGLYDLVKKKHMKGQDLLFRDKRQTECFYTFMAESV-
ISTAMPTATHSFIRNLQER-GKLMRCYTQNIDCLEDPIDLS-VVRLHGSMDRVKCTLCAASYDFTADYEDPPVCPQCET-GTLRPNIVLYNEEHPEGETI
GKLQTKPDLMIVMGTSLKIPALKKFIKQAHHKNGRVIFINRTAKEWDKVFDYEVLGD----------------------
>tr|A0A0C7BXQ9|A0A0C7BXQ9_9FUNG Putative Yor025wp-like protein OS=Rhizopus microsporus GN=RMATCC62417_10541 PE=4 SV=1
------------------------------------IQMSKRVLVITGAGISCNGGIPDFRSSDGLYSLVKKKHLKGKDLLFKSKEQTQCFYTFMAEKT-
IDAAMPTPTHSFIHGLQES-GQLMRCYTQNIDCLEDSLKLS-VVRLHGSMDKVKCTLCPASYEFTVDYEDPPVCPQCEM-GTLRPNIVLYNEDHPESEEI
GKVQTKPDLLIVMGTSLKIPALKKFIKQAHTKSGKVVFVNRTAKEWDSVFDYEVLGD----------------------
>tr|A0A068RH32|A0A068RH32_9FUNG Dhs-like nad fad-binding domain-containingprotein OS=Lichtheimia corymbifera JMRC:FSU:9682 GN=LCOR_00716.1 PE=4 SV=1
------------------------------------IKKSRRAIVITGAGISCSSGIPDFRSTNGLYNLVKARHLKGAELLFNDVAKTQCFYTFMAETL-
VSTAQPTPTHHFLRNMQSS-GQLLRLYTQNIDDLEHVVEVP-VVQLHGTMATVKCTLCSASYKFSEEYQNAPACPKCEA-GSLRPDIVLYNEDHPDGEKI
GLQQVKPDLLIVLGTSLKIPGIKKFIKLARNKNGTTIFVNKTPKEWENVFDFQIMGD----------------------
>tr|K0KRD4|K0KRD4_WICCF NAD-dependent histone deacetylase HST3 OS=Wickerhamomyces ciferrii (strain F-60-10 / ATCC 14091 / CBS 111 / JCM 3599 / NBRC 079
------------------------------------IINCKKIIMLTGAGISCNAGIPDFRSINGLYNLIPNSSIKGKDLLFNSINTITDFAKFMSNLE-
TQKAKPTKTHKFIEKINNQ-KKLIRCYTQNIDGLESQLGLSNVIQLHGDLNSLICTACFEKLNWSMEYIQLPECPQCIHQGRLRPNIVLYGENHPFSDII
TTGLNKPDLFIIMGTSLKVHGVKNLVKSMHQRGGKILLINKDF-GWNNIIDYQILND----------------------
>tr|A0A075AV36|A0A075AV36_9FUNG Sirtuin family domain-containing protein OS=Rozella allomycis CSF55 GN=O9G_003168 PE=4 SV=1
------------------------------------FLKAKRIVVITGAGISVSSGIPDFRSSGGLYDAAKSTKSQGKSLVFRDTEKMSEFFQFMAKKK-
CDEAKPSKTHNFLNLLAEN-KKMIRLYTQNIDCLEDRLSFEIVIKLHGSLDQVRCMTCSNTFEIEDSHVEAPECISCVE-GFLRPNVVLYNENHPSGDII
SSMVDKPDLLIVMGTSLKVHGLRQLVKQFHSEEGRVFFINKTPSEWIDIFDFQLLGL----------------------
>tr|A0A061B731|A0A061B731_CYBFA CYFA0S19e02256g1_1 OS=Cyberlindnera fabianii GN=CYFA0S_19e02256g PE=4 SV=1
------------------------------------IRRARKMAILTGAGISCNAGIPDFRSSNGLYNMTQQANAKGKELAFSSEESVRNFALFMSNLH-
TKDARPTKTHRFIADKIAS-KKVLRCYTQNIDAIEAKCGLNDVVQLHGDLNSLKCTSCNKTTQWTRRIINLPECPQCIDVGLLRPSIVLYGENHPNSEMI
TQGLNKPDFLLIMGTSLKVYGVKQMVKSIHAKGGLVVLVNRDP-GWTGIIDHQINMD----------------------
>tr|A0A0L8RAT2|A0A0L8RAT2_SACEU HST3-like protein OS=Saccharomyces eubayanus GN=DI49_4871 PE=4 SV=1
------------------------------------LGRSRKIACLTGAGISCNAGIPDFRSSDGLYNLVKEESKSGREMLFRDDFKISIFAKFMERSS-
VQLARPTKTHRFIAHLKNR-NKLLRCYTQNIDGLEEDMGLTDVVQLHGDLNTLSCTKCFQTFPWDRYWSRLPLCPHCEAVGFLRPNIVLYGENHPSGELI
TQGLNNPDLLIIMGTSLKVDGVKQLVKKLHDRGGLIILVNKSPSPWHGIIDYQIHSD----------------------
>tr|C4Y9C1|C4Y9C1_CLAL4 Putative uncharacterized protein OS=Clavispora lusitaniae (strain ATCC 42720) GN=CLUG_04799 PE=4 SV=1
------------------------------------IFKAKKTSILTGAGISCNAGIPDFRSDEGLYNIVKAKYIKGQDLLFRNATTLSIFCTFMEGQH-
SLRAKATETHRFIKTLKEK-NKLLRCYTQNIDSLEKTINLNDVVQLHGNLHKLCCTQCFSRYDWTPQNQKYPECENCHLIGILRPDIVLYGENHPQAEIL
ARGLNKCDCLLIMGTSLKVDGVKKLVKSLRERGGKVIFVNKTPKQWANLVDFQVLGD----------------------
>tr|G3B5F7|G3B5F7_CANTC DHS-like NAD/FAD-binding domain-containing protein OS=Candida tenuis (strain ATCC 10573 / BCRC 21748 / CBS 615 / JCM 9827 / NBR
------------------------------------IFKSKKATLLTGAGISCNAGIPDFRSSEGLYNLVKEKYVKGQDLLFRDELTLQVFCTFMEGAS-
SLQAKPTETHKFIKLLKDK-NKLLRCYTQNIDGIESKVNLTDVVQLHGDLNQLTCTQCFSNFEWTKKYQNNPECSNCFQIGILRPGIVLYGENHPQSEIL
AQGLNRPDILIIMGTSLKVDGVKKLVKSLHEKGGKVIFINKTQSQWDNYVDYQVLCD----------------------
>tr|A5DC33|A5DC33_PICGU Putative uncharacterized protein OS=Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / 
------------------------------------IFKARKSAVITGAGISCNAGIPDFRSSEGLYNLVKEKHVKGQDLLFRSKISLAVFCTFMESSS-
TLRATPTETHKFIKILKEK-KKLLRCYTQNIDGLERNIELKDVVQLHGDLHHLSCTHCFHTTQWTPKHKLNPECQNCFMIGLLRPAIVLYGENHPQAEIL
AQGLNKPDMLIIMGTSLRVDGVKKLVKTLHDKGGKVVFVNKTPTTWENIIDYEVLCD----------------------
>tr|A0A090C345|A0A090C345_KLUMA Uncharacterized protein OS=Kluyveromyces marxianus GN=KMAR_10371 PE=4 SV=1
------------------------------------IHRSRKCVVLTGAGISCNAGIPDFRSFEGLYRMVKEQYRSGQDMLFREEEKISVFASFMESSH-
TIQAKPTKTHEFIAHLKNR-GKLLRCYTQNIDGLEEMLGLQDVVQLHGDLTTLSCTQCFKVFSWSRYWKRLPVCPKCLESGMLRPNIVLYGENHPNADFI
TQGLNKADLFLIMGTSLKVDGVKRLVKTIHDRGGLVILVNKTTGSWHGIIDYQIEAD----------------------
>sp|Q9UR39|HST4_SCHPO NAD-dependent protein deacetylase hst4 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=hst4 PE=2 SV=1
------------------------------------IRKAKRIVVVTGAGISCDAGIPDFRSSEGLFSSLRAEYCSGKELVYRDLKSVNIFHAMIRKML-
SNNARPTDFHLFLSQLAQE-SKLLRLYTQNIDFLETRLEGLTTIPLHGTLEVVSCTRCSFLKKFNP---DVTVCPDCKT-GCLRPRIVLYNEIHPDSESI
GSVCSRPDCLIVAGTSCKIPGVKRIIKEMHKQKGNVIWLNYDEKDFLNLCDLVVQGD----------------------
>tr|S9X3U5|S9X3U5_SCHCR Sir2 family histone deacetylase Hst4 OS=Schizosaccharomyces cryophilus (strain OY26 / ATCC MYA-4695 / CBS 11777 / NBRC 106824 /
------------------------------------LRKAKRIVIVTGAGISCGAGIPDFRSSVGLFSSLRSEYCSGKELVYRDLKSVNVFHEMIKKEL-
SDNAAPTDFHHFLSKLAQD-SKLLRLYTQNIDFLETRLEGLTTIPLHGTLEVVRCTRCPFVRPFHP---GLTACPECRT-GCLRPRIVLYNEGHPDSDAI
GAVCSRPDCLVIAGTSCKIPGVKRIIKEMHRQKGSVIWLNFDSKEFSNLCDIIVEGD----------------------
>tr|G8BR29|G8BR29_TETPH Uncharacterized protein OS=Tetrapisispora phaffii (strain ATCC 24235 / CBS 4417 / NBRC 1672 / NRRL Y-8282 / UCD 70-5) GN=TPHA0C
------------------------------------LNRSRKIAVLTGAGISCNAGIPDFRSSTGLYDLVKSQYRTGQEMLFRDEMKIQVFATFMEKTS-
TRLAKPTKTHRFIAHLRNR-NKLLRCYTQNIDGLEELLGLEDVVQLHGDLNSLACTRCFHTFEWNRFLARLPSCPECLAAGFLRPNIVLYGENHQSSEFI
SQGINRPDFLIIMGTSLKVDGVKRVVKTMHEKGGIVILVNKTISQWAGIIDYQIVSD----------------------
>tr|Q6FRI7|Q6FRI7_CANGA Uncharacterized protein OS=Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) GN=CAGL0H08239g PE=
------------------------------------LNKSRKIILLTGAGISCNAGIPDFRSATGLYNLIKRQYGSGKEMLFRDEMKISVFATFMEKAS-
VKLAQPTTTHKFIAHLKNR-NKLLRCYTQNIDGLEENLGLADVIQLHGDLNTLACTRCYHEFQWSRYLARLPTCPECERIGYLRPNIVLYGENHPSGEII
TQGLNKPDLFIIMGTSLKVDGVQRVVKQIHERKGLVILVNKTKSRWNGIIDYQICCD----------------------
>tr|W0W2L5|W0W2L5_ZYGBA Related to NAD-dependent histone deacetylase HST3 OS=Zygosaccharomyces bailii ISA1307 GN=ZbHST3 PE=4 SV=1
------------------------------------LSKSRKIIVLTGAGISCNAGIPDFRSSSGLYDLVKKQFKSGQEMLFRDELKISVFATFMEKSS-
VRLAQPTKTHKFIAHLKNR-NKLLRCYTQNIDGLEEGLGLEDVVQLHGDLNTLACTKCFHVFPWNRFWCRLPTCPTCEETGFLRPNIVLYGENHPSSEFI
AQGLSKPDFFIIMGTSLKVDGVKRVVRQIHERGGIVLLVNKTSSSWHGLIDYQIMTD----------------------
>tr|A7TNZ2|A7TNZ2_VANPO Putative uncharacterized protein OS=Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294) GN=Kpol_495p15 PE=4 SV=1
------------------------------------LNRSRKIAVLTGAGISCNAGIPDFRSSNGLYDLVKNQFRSGQEMLFRDELKISVFATFMEKSS-
VQMAKPTKTHRFIAHLKNR-NKLLRCYTQNIDGLEETLGLINVVQLHGDLNTLACTKCFTIFEWNRFRARLPCCPSCEEVGFLRPNIVLYGENHPTGEFI
AQGLSKPDFLIIMGTSLKVDGVKKLVKHMHERGGVVILINKTISAWAGTIDYQICSD----------------------
>tr|C5DPR9|C5DPR9_ZYGRC ZYRO0A05566p OS=Zygosaccharomyces rouxii (strain ATCC 2623 / CBS 732 / NBRC 1130 / NCYC 568 / NRRL Y-229) GN=ZYRO0A05566g PE=4 
------------------------------------LNRSRKITVLTGAGISCNAGIPDFRSSSGLYEMVKKQFRSGQEMLFRDELKISMFATFMEKSS-
VKLAQPTKTHRFIAHLKNR-NKLLRCYTQNIDGLEENLGLEDVVQLHGDLKTLACTRCFHVFPWNRYWCRLPTCPQCEETGCLRPNIVLYGENHPSSDSI
AQGLNRSDFFIILGTSLKVDGIRKVVRQIHERGGIVLLINKTSSSWHGLIDYQILTD----------------------
>tr|I2H9M4|I2H9M4_TETBL Uncharacterized protein OS=Tetrapisispora blattae (strain ATCC 34711 / CBS 6284 / DSM 70876 / NBRC 10599 / NRRL Y-10934 / UCD 7
------------------------------------INKCKSFTVLTGAGISIKSGIPDFRSIDGLYNLIKLQYQSGKELLFRDSLKIEFFAKFIENNNY
IRCAKPTQTHYFIKHLQDR-NKLMRCYTQNIDGLEEMSGLIPVIQLHGDINNLQCIKCFQEFEWTRYYLRLPNCPNCIDDGFLKPNIILYGENHSKGEKI
SNIINKNSLFLIMGTSLKVDGIIRLVKNFHKQNGLIILVNKTKSIWSKYIDYQIVTE----------------------
>tr|J7RGU7|J7RGU7_KAZNA Uncharacterized protein OS=Kazachstania naganishii (strain ATCC MYA-139 / BCRC 22969 / CBS 8797 / CCRC 22969 / KCTC 17520 / NBR
------------------------------------LSRSKRIIVLTGAGISCNAGIPDFRSANGLYKQVKSEYSSGQEMLFRDEMKISVWATFMEKSS-
VQTARPTKTHRFIAHLKNR-NKMLRCYTQNIDGLENNLGLEDVVQLHGDLNTLNCTKCFHIVQWSRSYARLPSCPNCAEVGLLRPNIVLYGENHPSGEII
SQGLNKPDFFIIMGTSLKVDGVKKLVKQIHEKGGLVVLVNKTSSSWHGIIDYQIWED----------------------
>tr|H2AT78|H2AT78_KAZAF Uncharacterized protein OS=Kazachstania africana (strain ATCC 22294 / BCRC 22015 / CBS 2517 / CECT 1963 / NBRC 1671 / NRRL Y-82
------------------------------------INKSKKVVVLTGAGISCNAGIPDFRSSNGLYNLVKAEHGSGKEMLFRDEIKISVWATFMEKSS-
CRLAKPTVTHKFIAHLKER-NRLLRCYTQNIDGLEESLGLEDVVQLHGDLNSLACTQCFQTFPWSRYRSRLPNCPRCEECGILRPNIVLYGENHPSGELI
SHGLNKPDFFIIMGTSLKVDGVKNVVKQIHERGGIVILINKTSSMWHGIIDYQIWQD----------------------
>tr|R9K0B4|R9K0B4_9FIRM Uncharacterized protein OS=Lachnospiraceae bacterium COE1 GN=C809_04570 PE=4 SV=1
----------------------------------------GKIVAVLGIEMLVEGGGYDLDSNEETYRGYTPEDMLSTSFFNAKGERFFRFYKN--EILT
MEV-KSTPAYDALLRLQAQ-GKLSAVICQNFHGIPQGIRFHKIIELNGNMNSNRCPHCSKLFDIMRNAVGIPLCDNCKK-TAVRPNIRLLGERVKLMTEA
ENACEEADVLLIMGKDMYDDR---LEYSADPRSQLKILFSQEKQLSDRKVDFVIQDEIQLFLPV---------------
>tr|R9JWG9|R9JWG9_9FIRM Uncharacterized protein OS=Lachnospiraceae bacterium A4 GN=C804_00802 PE=4 SV=1
----------------------------------------KSIVAVLGIEMLVEGGGYDLDTNEENYRGFSPEDMLSTSFFNAKVEKFYRFYKK--EILG
MQL-HSTPAYEGLEKLQQQ-GKLSAVICQNFHGIPKTVHLDKVIDLNGNIYINQCPHCDKGFDIIINSKGIPQCDRCKM--AIRPGIRLIGERVELMTQA
AVACDKADVLLILGKNMYHDK---LEYSVAPHEQLKVLFSKNEFERNSKVDFIIRDDISEFLPL---------------
>tr|A0A0J1G591|A0A0J1G591_9FIRM Uncharacterized protein OS=Robinsoniella sp. RHS GN=RHS_3412 PE=4 SV=1
----------------------------------------EYLVALGGLNMMREVGISHYHDKDEAYRGYSPEELFSARCFATNPEKFYNYYKD--DILA
TNEEEPGPAYYALAKLEAM-GRLKYIITREIYNLPQRAGCKKVINLHGNIYENHCPRCLKQFTLIKKAEGVPFCDECNI--PLHPGVRLVGEMVHVMSKA
AEEVAKADVLLVLGLHLKTEL---CRECIQYQGQRLILINSQEHYADNVADMVYHDNVQTFFPN---------------
>tr|C6LB43|C6LB43_9FIRM Transcriptional regulator, Sir2 family OS=Marvinbryantia formatexigens DSM 14469 GN=BRYFOR_05838 PE=4 SV=1
----------------------------------------RYLVAIAGSGMQRECGHQSLRDQERAYNGYSPEEMFSSAFYNTRTEPFYNFYKK--EILS
Q-DLKPGPAYKALAKLERK-GILKAVITREIYGLNREAGCKNVLELHGNIGNNHCPRCGRTYSKLKDAKKVPLCEDCML--PIRPGIRLFGEMVSQMTRM
ANEISRADVLLVLGARLDPEF---CEHNLSYKGDKVILLTNRENHGDVKADYVIHGKLNELVPQ---------------
>tr|B0G321|B0G321_9FIRM Transcriptional regulator, Sir2 family OS=Dorea formicigenerans ATCC 27755 GN=DORFOR_00642 PE=4 SV=1
----------------------------------------KYTTVLSGFEMLQENGYPAIRDGEESYDGYSVDEMFTSAFYSTRKPQFFEFYRN--ELLS
ALDIPPGKGYLEMAELEEK-GLFQTIITRRVFGLPERAGCKNVINLHGSVYENYCPHCGKKYPVIREAKRVPLCTECNA--PIRPGVCLMGEKVAVITKA
ADEVQKADVLLVLGTNLKTYL---CTQLINYEGDKLIVVNPEPHFSDKYADILVSERVDITLEK---------------
>tr|A0A0K9NB68|A0A0K9NB68_9FIRM NAD-dependent deacetylase OS=Dorea sp. D27 GN=HMPREF0980_02675 PE=4 SV=1
----------------------------------------RYTTVLSGFGMLLESGYPAIRDGDESYEGYSVEEIFSSSFYSTRKEQFYEFYRN--EILK
MLDKPPGKCFYEMAELEKR-GLVQSVITRRIYGLPQRAGCKNVVNLHGSVYENYCPHCGKEYPVITGSKRIPLCQVCST--PIRPKICLFGEMVRVITEA
AEEVRKADVLLVLGTNLKTYL---CSQLIDYEGDKLVLINPEKHFSDKLADVIVHKSVEDALGE---------------
>tr|R9MLY7|R9MLY7_9FIRM Uncharacterized protein OS=Lachnospiraceae bacterium 3-2 GN=C818_00485 PE=4 SV=1
----------------------------------------KYTTVLSGYAMLEESGYPAIRDGEASYDGYSADEMFSSSFYTARTEQFFSFYRN--EILS
ALDKPPGKCFYEMAELERR-GLFNCIITRRVFGLPETAGCKNVINLHGSVYVNYCPHCKKNYSLVRNSKRVPICEDCST--VIRPGVCLFGEMVQVITRA
AHEVQKADVLLVLGTNLKTQL---CKQLVQYEGKKLILVKETPHFADRYADLVVNERVDDTLEK---------------
>tr|R6RET7|R6RET7_9FIRM NAD-dependent deacetylase OS=Firmicutes bacterium CAG:424 GN=BN652_01383 PE=4 SV=1
----------------------------------------TYTVALCGSGVVKECGQRTLKTPQMAYEGVSPEEIFTTVYYNNRTAQFFEFYKE--EILK
KPA-KVTETARALKKMEEA-GKLQCIIDSNIYQQMKCGGCKNVIALHGSIYENTCPHCGKIYSMMRDSEKIPRCESCGT--VIRPGVKLFGEMMTIMSEA
SSQVEQADVLLLLGTSVASEV---YSKYLNHEGRYLILIHKERQFLDERADLLILEEPRKVLEK---------------
>tr|R9NFB1|R9NFB1_9FIRM Uncharacterized protein OS=Dorea sp. 5-2 GN=C817_00186 PE=4 SV=1
----------------------------------------KYTTVLSGFGMLLESGYPAIRDGEVSYDGYSMEEMFSSAFYSTRKEKFYNFYRN--ELLS
QLEKPPGKGFTGMAELERR-GLIQCIITRRIFGLPRRAGCKNVIDLHGNVYDNFCPHCGRTYPMIRDSVRVPLCEHCKT--PVRPRVCLFGEMVRVITRA
AEEIQRAEVLLVLGTNLKSYL---CSQLTDYGGQKLILVNETPHYSDRFADIVIHQRVDDLMER---------------
>tr|F0Z4F1|F0Z4F1_9CLOT NAD-dependent deacetylase OS=Clostridium sp. D5 GN=HMPREF0240_04002 PE=4 SV=1
----------------------------------------KYTVAMSGIEMLLENGYPGLRDGEESYEGYSAEEILSSAFYATRKEIFFEFLRN--EMLA
ATAVPPGTGFENLKKLEEY-HLVHSEITKRLFGLLERAGCRNVINLHGSIYDYFCPHCGKKYSIIRETEGVPLCESCKN--TIRPKICLFGEMVSIVTKA
AEEIQKADVLLVLGTSLHAAL---CHQLIQYNGDKLILITNEEHYSDRLADVLVYSRVDDALEK---------------
>tr|S2YLP0|S2YLP0_9FIRM Uncharacterized protein OS=Coprococcus sp. HPP0048 GN=HMPREF1216_01137 PE=4 SV=1
----------------------------------------KYTVVLSGNGMVLESDYMLIRDSQESYDRYSAEELFSSSLFSTRKELFYEFYRN--EMLP
QLEKPPGEGFYALAALEKK-GLIDTVITRRVYHLPTRAGCKNVIELHGNICEHYCPHCGEEYSLIRQSRRVPLCTKCNT--ALRPRAVLYGEMVQVMTKA
AEEVMRADVVLALGTNLKTTL---CEQLLGYGGNKLILITLKEHFSDKYADGVIHDRVDQTLLK---------------
>tr|R6VGK2|R6VGK2_9FIRM Uncharacterized protein OS=Firmicutes bacterium CAG:227 GN=BN546_01036 PE=4 SV=1
----------------------------------------KYLVCLLGMRVSYQSGCTNIGEPEDAYDGYSPEELFSAAFYNTRPSQFYEFYKN--EVLS
KRG-RINEGLKLLGQLEEM-GILKSIVTRDIYSLPKRAGCKNVLEIHGSIYRNICPRCRKKYPLLQERSGLPYCEKCGS--IIRPEIYLKGEMIRLLTKA
VDEVSSADVLLMLGCSMRSEL---GSMFTKYKGEKIILMNDQDHFADGKADLVIDGKAMDLMKG---------------
>tr|R5BU07|R5BU07_9FIRM Uncharacterized protein OS=Blautia hydrogenotrophica CAG:147 GN=BN499_02287 PE=4 SV=1
----------------------------------------DYLVILKGIGVSMECGCTSYRRSKYAYEGRSPEEIFSAGFYNTRVREFFEFYKN--DLIS
SLG-EINDGLKTLKKLEDM-GVLKMIITRDIFSLAHRAGCKNVIELHGSVYHNECPHCRRKYPLIRDSKGVPRCENCGT--TIRPQIVLAGEMVALSTKA
ADEVSKADTLLLLGCDMSSVL---AESFLRYTGKRVILIHNREHYADSKADLVIHGKSMDILAQ---------------
>tr|R6Q196|R6Q196_9FIRM NAD-dependent protein deacetylases SIR2 family OS=Ruminococcus sp. CAG:55 GN=BN703_01423 PE=4 SV=1
----------------------------------------KYLVCLAGMEFMREQNVAYHRDSDESYRGYSPEELFSARMFNTHAELFYEYYRN--EILS
KHL-EAGKGNEALARLEEA-GYLKTIITKGIYNMPQKAGCKNVINMYGNIYENACPRCGKIFPIIKNSDKVPLCDVCKS-TVIHPGVYLHGEMLTVISHA
VEEVAKADTILVLGMNLNSSL---CKDMLPHTGKDLIVIHKEPHYLDEKATAAYHGAVSKILPE---------------
>tr|R5T744|R5T744_9CLOT NAD-dependent deacetylase OS=Clostridium sp. CAG:75 GN=BN771_01478 PE=4 SV=1
----------------------------------------DHIVLISGLGVARAAGLNGVRAEHIAYDGYSNDEIISSMFLSKRVEIFYQYYKE--IILN
CA-LQPTSIHEGALRLQQA-GKLDAIVKRTVYPLYEMAGCDDVIELHGSVEKNYCPNCGKVYGSIRHAVGIPSCTKCGV--PLRPGFTLLGEMVGKISAA
ANAVENADLLLIVGTSIRSPL---CLNLTKYKGDKMLLLNTHEMVGDDRANYRAYGDLCELFKY---------------
>tr|R6MT15|R6MT15_9CLOT NAD-dependent deacetylase OS=Clostridium sp. CAG:253 GN=BN565_01167 PE=4 SV=1
----------------------------------------GNIVVLAGMNITYDIGLNGVTAEHIAYDGYSNDEIASSLFYTRRAELFFKYYKE--VILN
IENPQPSSIHYGIYKLQQC-SKLSAVVTRSVYSLYEKVGCNNVIQLHGSVDKNICPKCKKLYDSIKHSEGIPVCEQCGI--PLRPGFSLLGEMLGKISQA
SNAVENANILLVLGASINSTL---CRYMVKYNGDKLLLLNDKEKVGDERANYRAYGNIREMFAK---------------
>tr|R6DI02|R6DI02_9CLOT NAD-dependent deacetylase OS=Clostridium sp. CAG:230 GN=BN547_00230 PE=4 SV=1
----------------------------------------DNVVLVSGSEVMRETGLNGIRAEHMVYEGYSGEEIITSPFFSRQVDTFYDYYKN--VILN
KTNVEPTAVYKAAAKLEKA-GCISHIVTRMIYGLHQKAGCKNVIELYGSAEENRCPVCGKIFGSIKKAPGTPKCDKCNI--VLRPGFSFFGEMIGRLTKA
CNAVENADVLLVVGMALSSHT---WASTLRYEGDKLVLISNEEHPGDEKANYRMYGNLSEIFTY---------------
>tr|R6VJD2|R6VJD2_9FIRM NAD-dependent deacetylase OS=Roseburia sp. CAG:380 GN=BN635_00759 PE=4 SV=1
----------------------------------------RNIVVLSGLNTMRETGLNGVRAEHLAYEGYSNDEIVSSAFYARRSDIFYDYIKN--VTIN
KE-AVPTVVHKAVRQLQQK-GKVPHIITRTVYELYQKAGCEHVLDMHGSIEKNICPACGKLFDMIKESKGEPVCDKCRI--PIRPGFILLGERVGKVSEV
CDIVESADVLLVLGSAVRDPI---CQHFERYKGNKFILVNTEEKLGDTRADYRLYGCLSEIVPY---------------
>tr|A0A0Q1L8E7|A0A0Q1L8E7_9FIRM Uncharacterized protein OS=Lachnospiraceae bacterium TF01-11 GN=APZ18_12540 PE=4 SV=1
----------------------------------------GNIVVLAGMNITYDMGLNGVNAEHLAYDGYPNDEIVSSSFYTRRAPLFYKYYKE--VILN
IDDPQPSPIHYGIYKLQQC-SKLSAVVTRSVYSIYDKVGCSNVIKLHGSVDENVCPRCKRLYDSIKHAKGIPVCEKCGI--PLRPGFTLVGEMLGKISKA
STIVENADILLVLGAGINSTL---CRYMVKYQGDKLLLLNDIEKVGDDRADYRAYGNLRDMFAQ---------------
>tr|R7JZ56|R7JZ56_9CLOT NAD-dependent deacetylase OS=Clostridium sp. CAG:277 GN=BN584_00676 PE=4 SV=1
----------------------------------------GNIVVLSGLNVMRETGLNGVRAEHLAYEGYANEEIISSAFYARRSEIFYDYIKN--VTIN
KETAEPTVVHKAIRQLQQK-GKVPRIITYTVYGLYENAGCENVLDIHGSIQKNKCPACGKIFDMIKDSVGEPLCDACKV--PIRPGFLLLGERVGKMSEA
CDDIEAADVLFVIGFGIRESL---CQHLHKYKGNKLILVNTEEKLGDERADYRIYGKISEIVPY---------------
>tr|E7GIL5|E7GIL5_CLOSY NAD-dependent deacetylase OS=[Clostridium] symbiosum WAL-14163 GN=HMPREF9474_00758 PE=4 SV=1
----------------------------------------NYTVALCGSGMTEESGFIGIKKPERAYEGASPEEIFTSSYYNTRPMQFFKFYHE--EILD
KIP-EPGPSSHIMAAMERA-GHLHCIITSNIFDQEKRGGCENVIDLHGTIFMNRCPHCGEYYSVIQNSKGVPYCMICHS--VIRPLVSLFGEMVRIMTRT
TEEIEKAEVLLLLGTTMQSEV---FSNYVRYNGHNLIIIHKEEHYMDHKADLVIVEEPGNVLCQ---------------
>tr|D4CG93|D4CG93_9CLOT Transcriptional regulator, Sir2 family OS=Clostridium sp. M62/1 GN=CLOM621_08465 PE=4 SV=1
----------------------------------------NYTVALCGSGMMTEGGVTGIKAPERAYEGASPEYIFTSAYYNTRPEKFFNFYKE--EILK
HIP-EPAAGSYVMARMEAA-GKLQCIITANVYNQAIRGGCEHVINLHGSVFENQCPHCGELYTVMLNAKGIPSCRVCNS--TIRPKVSLFGEMVRIMTRT
TEEVEKAEVLLLLGTTLRSDV---FSNYFRYHGKYLVAIHRTPHYSDAKADMVIIDEPGHVLEQ---------------
>tr|R6YVP2|R6YVP2_9CLOT NAD-dependent protein deacetylases SIR2 family OS=Clostridium sp. CAG:299 GN=BN593_00830 PE=4 SV=1
----------------------------------------NYTVALCGSGMLTDGGVRGIKNPDRAYAGASPEYIFTSAYYNTRPEQFFHFYKE--EVLR
YIP-DPGLGSYAMARMEQA-GKLQCVITANVFNQAIRGGCEHVINLHGTVYENQCPRCGELYTVILEMKGIPCCRVCNA--TIRPKVSLFGEMVRIMTRT
TEEIEKAEVLLLVGTTLRSET---FSNYLKYHGKYLAVLHRTPHYSDEKADLTLIGEPGQILSQ---------------
>tr|R6BMI5|R6BMI5_9FIRM NAD-dependent protein deacetylases SIR2 family OS=Firmicutes bacterium CAG:56 GN=BN708_01693 PE=4 SV=1
----------------------------------------HYTVALCGSGILAETGCRTFQNQDYAYEGRSPEDIFASAYYMTRPDSFFEFYRA--EVLE
KDW-KPSESCYALKKLEDA-GKIQCILSDNIFDLEKRAGCSNVLSLRGSIYQNRCPKCGQEYPMIRDSKKTPRCRNCNN--VVRPGVTLYGEQLHLTSLA
ATEVEKAEVLLLLGTKLSSDV---YSNYVKFEGEQIVVIHEKEHYTDCKADIVIYDQPGKVLSN---------------
>tr|G5HPS6|G5HPS6_9FIRM Uncharacterized protein OS=[Clostridium] citroniae WAL-17108 GN=HMPREF9469_04588 PE=4 SV=1
----------------------------------------TYTVALCGSGMMEEGGFIGIKKQDKAYDGYGVEEMYSSAFYNTRPEQFFEFYKN--EMLH
NAP-RDTPTGPALAAMERD-GKLQCVIDSNIYDSPRRGGCRQVVNLHGSIYQNQCPRCKKKYPLIMNARRVPICETCNI--PVRPMISLVGEMVQNMTKT
TEEITKADVLLLLGTTMASEV---FRQYIKYTGSHIVIIHKQEHYLDKEASLVILDYPMNVLPK---------------
>tr|R5U371|R5U371_9CLOT NAD-dependent deacetylase OS=Clostridium hathewayi CAG:224 GN=BN544_01455 PE=4 SV=1
----------------------------------------RYTVAICGSGMMEEGGFIGVKNPDKAYDGYSAEEIFSSAFYNTRPEFFFEFYKK--EMLD
NPP-EDTASGPALAAMERA-GKLQCLITSNIYAKAQRAGCKNVINLHGTIYENKCPHCGKDYTMVRDAKKILLCDKCGI--PVRPQVSLFGEMVRRMTKT
SNEISKAEVLLLLGTTLDSEV---FGNYVKYTGRWLVIIHPNRNYLDDKADMLFLDYPKNILPK---------------
>tr|F7KE23|F7KE23_9FIRM Uncharacterized protein OS=Lachnospiraceae bacterium 3_1_57FAA_CT1 GN=HMPREF0994_04102 PE=4 SV=1
----------------------------------------SYTVALCGSGMMEEGGFVGVKYADKAYDGHSPEEIFTSAFYHTRPKQFFDFYKE--EMII
NAP-EPTDSGRVLAAMEQA-GKLQCVISSNIYELSQRAGCKNVIDLHGSIYHNYCLRCGREYSVIKHVKGIPACEKCGI--PIRPGLFFFGEMTHLISQA
SQAIHDAQVLLLLGTTLNSEV---FAHYLKYHGKWLIMIHKERHFLDDNADMVFIDQPKNILSQ---------------
>tr|U2BCA4|U2BCA4_9CLOT Transcriptional regulator, Sir2 family OS=Clostridium sp. KLE 1755 GN=HMPREF1548_02970 PE=4 SV=1
----------------------------------------SCTVALCGSGMMEEGGYIGVKNPDKAYDGYSPEEIFTSAFYNTRPKLFFDFYKQ--EMLN
GGP-EPTESETVLEKMEQD-GKLQCIITSNIYELCQRSGCKNVIELHGSIYHNICQRCGREYPVIKQAHGIPVCEDCQI--PIRPGLFFFREMAQLVTQA
VEEINRAEVLLLLGTNLNSEV---FSHYIKYQGKYLVIIHQRSHYLDDNADMVFIDQPKNILSR---------------
>tr|R5R6I7|R5R6I7_9FIRM NAD-dependent deacetylase OS=Firmicutes bacterium CAG:646 GN=BN747_02553 PE=4 SV=1
----------------------------------------SYTVAICGSGMMEEGGYIGVKFQERAYDGVSPEELFTGSYFNTRPEQFFRFYKN--EMLR
HMP-QKTESWDALAAMERA-GKLQCVISANIFSMGKKVGLKNFIELHGSVYQNRCSRCGKEYSMVRDSKGIPMCTECEG--MIRPQITLFGEMVRLITQV
TEEIERAEVLLLLGTTLNSEV---FGQYIRYNGKKLVVIHQREHYEDHHADLAIIEQPRKVLPY---------------
>tr|C5EHP8|C5EHP8_9FIRM Transcriptional regulator, Sir2 family OS=Clostridiales bacterium 1_7_47FAA GN=CBFG_01443 PE=4 SV=1
----------------------------------------NYTVALCGSGMMEEGGFIGIKKQDKAYDGYGVEEMYSSAFYNTRPEQFFEFYKK--EMLH
NAP-RDTASGPALAAMERA-GKLQCIIDSNIYDKPRRGGCRHVINLHGSIYQNQCPRCKKKYPVMAQARRVPICPSCNI--PVRPMISLIGEMVQNMTKT
TVEITKADTLLLLGTTLASEV---FRQYIEYTGRNIVIIHKQEHYLDKEAALVILDYPMDVLPL---------------
>tr|A0A0E2HKX5|A0A0E2HKX5_9FIRM Uncharacterized protein OS=[Clostridium] clostridioforme 90A8 GN=HMPREF1090_03403 PE=4 SV=1
----------------------------------------TYTVALCGSGMMEEGGFIGIKKQDKAYDGYGVEEMYTSAFYNTRPERFFEFYKK--EMLH
NAP-RDTASGPALAAMERA-GKLQCVIDSNIYDKALRGGCRYVINLHGSIYQNQCPRCKKKYPIIAGAKRIPICRDCNV--PIRPMISLIGEMVQNMTRT
TEEITKADTLLLLGTTLASEV---FCQYIQYAGRNMVIIHKQEHYLDKDADLVILDHPMNVLPQ---------------
>tr|C0CZD4|C0CZD4_9FIRM Transcriptional regulator, Sir2 family OS=[Clostridium asparagiforme] DSM 15981 GN=CLOSTASPAR_02361 PE=4 SV=1
----------------------------------------RYTVALCGSGMMEEVGLKGLKREDRAYEGASPEELFNIACYSRHPERFFQFYRE--EILK
QEM-QISPAVYELAAMERA-GKLQCLVTINLHDAPIKAGVKHAICLHGSVYHNRCPRCGRQYGVMINSVPVPLCQDCHA--VIRPGVSLFGEMVHSMSRT
AQEISRADLLLLLGTSLRSDV---YSQYIRYKGSGLIMIHRLPRPLDEKADLVVYDMPQNVLPG---------------
>tr|G5HD26|G5HD26_9FIRM Uncharacterized protein OS=[Clostridium] citroniae WAL-17108 GN=HMPREF9469_00488 PE=4 SV=1
----------------------------------------SYTVAVCGSGMMEEGGILGLKEEGRAYEGESPEELFHISCFSRRPEIFYDFYKK--EILE
KVP-SMTPSVEAMAEMERQ-GRLQCVVTTSIFDLPKAAGVENVIYLHGGIYDNTCTHCGKKYSMMKNSKHIPLCEDCGH--IIRPGTFLYGEMVGLMSRT
AEEISRAEVLLVLGTSLRSEV---YSHYIRYQGKKMIIIHRAPRPLDEKADMVVYDLPQNILPL---------------
>tr|R0C4P1|R0C4P1_9FIRM Uncharacterized protein OS=[Clostridium] bolteae 90A9 GN=HMPREF1085_01727 PE=4 SV=1
----------------------------------------SYTVAICGSGMMEEGGILGLKQEGRAYESESPEELFHISCLSRRPERFYEFYRE--EILK
KIP-DMTPSVRALARLEEE-NKLQCIVTTNIFDLPEQVGCRNVIYLHGSIYKNRCPHCGRLYSMIRDSRHVPHCKNCKT--MIRPGTSLYGEMVSIMSRT
TEEIARADVLLVLGTSLRSEV---YSNYIRYQGRKMVIIHRIPRPLDEKADMVIYDLPQNVLPL---------------
>tr|C5EK15|C5EK15_9FIRM Transcriptional regulator, Sir2 family OS=Clostridiales bacterium 1_7_47FAA GN=CBFG_00516 PE=4 SV=1
----------------------------------------RYTVAVCGSGMLEEGGILGLKQEGRAYEGQSPEELFHISCFSRRPELFYDFYRR--EILE
KIP-RMTPSVEALTEMERR-GMLQCMVTTSIYDLPRSAETKNVIYLHGGIYENTCIHCGKHYSMIRNSRHVPLCEDCGH--IIRPGTFLYGEMVQMVSRT
TQEISKADVLLVLGTSLRSDV---YSHYIRYQGKKMIIIHRAPRPLDEKADMVIYDLPQNVLPL---------------
>tr|A0A0J1GF16|A0A0J1GF16_9FIRM Uncharacterized protein OS=Robinsoniella sp. RHS GN=RHS_0194 PE=4 SV=1
----------------------------------------RYTVVLCGSGMMEEGGYTGVKKPLRAYEDASPEEIFSSAFYSTRPEQFFDFYIH--EMLQ
NPP-VITESGPALAAMEQA-GKLQCIITANIYEHGRQMGCKNIINLHGSIYHNQCPRCKKEYTLMLNAKGMPICETCKI--PIRPMVSLFGEMVRLMTKT
TEEIEKADVLLLLGTTLTSEV---FVNYIKYEGSNLVIIHDQEHYTDTKADLVIIEEPRKVLPL---------------
>tr|A0A067PHW8|A0A067PHW8_9HOMO Uncharacterized protein OS=Jaapia argillacea MUCL 33604 GN=JAAARDRAFT_142547 PE=4 SV=1
-----------------------------------AIAKSKRIVVVTGAGISCSCGIPDFRSPDGLYNLRDLFDAS----LFRDPTSASVFYTQLKRSID
--SATPSATHAFLKTLDVK-GNLLRSYTQNIDGLEERSGLVRNVQLHGDIHRVRCTFCSAELTCTKEHMEAPDCPECSAVGTLRPAIVLYDEPHPLGDEI
GTIQRKPDLLIIMGTSLKVHGFAKAVHSTSRKKRKVIFVNKTPS--GSEWEGIIDYHVMGGSDEWVTRVLDDWK-----
>tr|A0A0D7AIY2|A0A0D7AIY2_9AGAR Putative member of the Sir2 family of NAD(+)-dependent protein deacetylase (Fragment) OS=Fistulina hepatica ATCC 64428 GN=FISHE
-----------------------------------SVVNSRKIVVVTGAGISCSCGIPDFRSSDGLYNLRDLFDAS----LFRDPTSTAIFYTKLKQSID
--KVQPSETHKFLYTLEKH-KRLLRSYTQNIDGLEGKVGLMRNVQLHGDIHAVRCMSCSAEFPCTSEHLSPPDCPECLKVGSLRPAIVLYDEPHPLGDVI
GTIERRPDCLIVMGTSLKVHGLARTIHTAKKGTGKVIFVNRTPP--SAEWGSVFDYYVSGETDAWVMRVLKDWK-----
>tr|A0A0C9WLM6|A0A0C9WLM6_9AGAR Unplaced genomic scaffold K443scaffold_657, whole genome shotgun sequence (Fragment) OS=Laccaria amethystina LaAM-08-1 GN=K443D
----------------------------------------------TGAGISVAAGIPAFRGANSRHQ-EDLMSMR----VLLS----TEQCQSLAKTAA
--LARPTTFHELLGTLEKE-NILHRLYTQNIDALELKVGLDRCIPLHGSLTYVKCTVCHSRQRMEY-HFQPPTCPACLKVGQLRPDILLYGELNPWEDIT
AGIIITPAVLLVVGTSIKIRGIGPEVKA---KGGHVININQTPS--ESVLRRFFDLEVLEDCQVFAQLLIQRFQ-----
>tr|A0A0C3MJK3|A0A0C3MJK3_9HOMO Uncharacterized protein (Fragment) OS=Tulasnella calospora MUT 4182 GN=M407DRAFT_65110 PE=4 SV=1
-----------------------------------AVAKSKRVVVVTGAGISCSCGIPDFRSTDGLYNLRDLFDSS----LFRDPTSTAVFYTGLKSSID
--NAQPSPTHRFIKTLDSK-GKLLRSYTQNIDGLEERVGIVKNVLLHGDIHRVRCTLCSANFTCEQRHLDPLDCPECSSVGILRPAIVLYDEPHPLGEEI
GAIERKPDLLIIMGTSLKVHGLAQAVHQNRGLLNKVIFVNKTAP--GSEWADVIDYHVQGLTDAFVEKVVEDWK-----
>tr|F4PDA9|F4PDA9_BATDJ Putative uncharacterized protein (Fragment) OS=Batrachochytrium dendrobatidis (strain JAM81 / FGSC 10211) GN=BATDEDRAFT_14620 P
-----------------------------------ALYASKRCIVVTGAGISVDAGIPDFRSEDGLYNLRDLFDAS----LFNDPISTRLFYTELRRLTA
--NARLTRTHQFIKDIATS-NRLLRCYTQNIDCLESRLGLTQVVQLHGNLETVVCAFCQTVSEFTDEIAAPPSCSACENVGLLRPNIVLYNEHHREGDKI
SQLQKKPDMLIVMGTSLKVVGVAKRVHA----NGICVFINATVA--VKEWESIFDYQVIGRSDDVVSCL----------
>tr|G3ANU5|G3ANU5_SPAPN Putative uncharacterized protein (Fragment) OS=Spathaspora passalidarum (strain NRRL Y-27907 / 11-Y1) GN=SPAPADRAFT_61129 PE=4 
-----------------------------------CIAKAKKCTVLTGAGISCNAGIPDFRSSDGLYNLQDLFDIS----LFRDEISLSLFCTSLYKSSL
--KATATETHKFIKVLKDK-NKLLRCYTQNIDCLESTMNLLDVVQLHGNLHKLSCTSCFSNFDWNEKFQSNPECSVCYAIGVLRPDIVLYGENHPQSELL
SQGLSKPDLLIIMGTSLKVDGVSKSIHE---KGGKVIFINKTPL--SKQWKNVIDYEVLTDCDDFVRILKREI------
>tr|A0A0H5BXW4|A0A0H5BXW4_CYBJA HST3 protein OS=Cyberlindnera jadinii GN=HST3 PE=4 SV=1
-----------------------------------QLSKSRNMIILTGAGISCSAGIPDFRSADGLYARKDLFDVM----VFQRGEHVSQFCKDLRTRSL
--NAKPTRTHRFIQRQLRS-KRALRCYTQNIDGVEHRMGLLECVQLHGDVHTLRCTHCSTVVDWTPELEGLPECHECLNTGVLRPNVVLYGENHPLAETI
ATGLSKPDMLVIIGTSLKVHGVAKAVHA---RGGVVLLINDT-T--LKGWDNVIDYQVLGDCDSFFALHEAHSQ-----
>tr|A3LZ70|A3LZ70_PICST NAD-dependent deacetylase HST3 (Homologous to SIR2 protein 3) (Fragment) OS=Scheffersomyces stipitis (strain ATCC 58785 / CBS 6
-----------------------------------HIFKAKRTTVVTGAGISCNAGIPDFRSSDGLYNMQDLFDIS----LFRNEMSLAVFCTGLYKSTL
--VAKPTETHRFIKILKDK-NKLLRCYTQNIDSLESTINLLDVVQLHGNLHKLSCTNCFTNFDWNEKYQSNPQCSKCYEIGLLRPDIVLYGEHHPQSEIL
AQGLAKPDMLIVMGTSLKVDGVSASVHA---KGGKVIFINKTPL--AKQWDSVFDYEILSDCDSFVRLLKNEV------
>tr|A0A0D7ASX0|A0A0D7ASX0_9HOMO DHS-like NAD/FAD-binding domain-containing protein OS=Cylindrobasidium torrendii FP15055 ss-10 GN=CYLTODRAFT_231437 PE=4 SV=1
-----------------------------------SVSKCKKIVVVTGAGISCSSGIPDFRSSDGLYALRDLFDAS----LFRDTTSTSVFYTQLKQSVD
--SAQPTPTHNFIKLLDFK-GRLLRSYTQNIDGLEERAGLVRNVQLHGDIHRVRCIACSADYLCTSEHITSPPCPDCTQVGTLRPAIVLYDEPHPLGDDI
GSIQKKPDLLIIMGTSLKVHGLAKAVHSMKKPGGKVVFVNKTAP--GSEWADIIDYHVLGETDEWVSRVEETWR-----
>tr|J0WV84|J0WV84_AURST DHS-like NAD/FAD-binding domain-containing protein OS=Auricularia subglabra (strain TFB-10046 / SS5) GN=AURDEDRAFT_72640 PE=4 S
-----------------------------------QLSRSKRLVVVTGAGVSCSSGIPDFRSPRGLHNLRDLFDAS----VFRHADTAALFYSELKDRID
--KTTPSPTHKFLAKLGIE-KRILRIYTQNIDGLEVRAGLLSVIQLHGDIHRVRCVLCSAVYPCSPDIVTAPECPECAQIGILRPAILLYNEVHPDESTI
GTFFRGPDFLLIIGTSLRAHGIGRELHS-AEPGVRIVLVNETAP--SAEWKDIIDVHIAASCDEWVARVLDDWS-----
>tr|U9T144|U9T144_RHIID Uncharacterized protein OS=Rhizophagus irregularis (strain DAOM 181602 / DAOM 197198 / MUCL 43194) GN=GLOINDRAFT_69574 PE=4 SV=
-----------------------------------YIKSAKNIVVIVGAGISVSGGIPDFRSPDGLFAERDLFDLSR---IFISSRSLTTFYKLLKQQVI
--SARVTATHHHFAKLNNT-NKLLRVYSQNVDNLEERAGLDRIVKLHGEIDNVWCNICHKTFPFSSDVINPPECQYCMEPMLPRPNILLYNDFETVGEEI
GRVARKADCLLIMGTSLKVSGCSKAVHN---RGGKVIFINTTVA--TNNWEGVIDVHIQGASDDWAELVEAELE-----
>tr|Q6CAJ8|Q6CAJ8_YARLI YALI0D02145p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_D02145g PE=4 SV=1
-----------------------------------ILGKCKRVVCVTGAGISCSAGIPDFRSQQIAIGKRELFDAS----ILKREDTTLTFMSALKQQCQ
--ASRPTRVHEFVAKLDTA-GKLLSCYTQNIDSLEHKTEVKKIVQLHGHLDTLNCIQCSEKLQWKDRVKEMIACPTCEAVGWMRPNVVLYGEPHPEAEEI
GSRIKRPDCLVVIGTSLAVTGIAQEVKA---NGGHVIFINKTPAK-ISGFSENVDYFIQGDCDAYMRDLADRWP-----
>tr|F8PFL8|F8PFL8_SERL3 Putative uncharacterized protein OS=Serpula lacrymans var. lacrymans (strain S7.3) GN=SERLA73DRAFT_44108 PE=4 SV=1
-----------------------------------AVAKCKKIVVVTGAGISCSCGIPDFRSSDGLYALRDLFDAS----LFRDSTSTSVFYTQLKRSID
--SASPAPTHNFIKTLEAK-QKLLRSYTQNIDGLEERVGLVRNVQLHGDIHRVRCTFCSAEFPCIEEHLKAPDCPECFAVGTLRPAIVLYDEPHPLGDDI
ATIQRKPDMLIIMGTSLKVHGLAKTIRTSKSWTGKVIIVNKTPP--GSEWSDIIDYHVAGETDRWVERVLEDWK-----
>tr|J0WMT8|J0WMT8_AURST DHS-like NAD/FAD-binding domain-containing protein (Fragment) OS=Auricularia subglabra (strain TFB-10046 / SS5) GN=AURDEDRAFT_3
-----------------------------------LVGSSRRIVIVTGAGVSRSSGIPDFRSANGLYSLSDLFDAS----IFRDGHSASLFYSELKAVID
--KAKPSPTHHFMKAMLNE-GRLLRVYTQNIDGFETQCGLINVVQLHGDIHRVRCIICSASYHSSQEFANAPKCPECEKTGTLRPDIILYNESHPDSDDV
SAFCRRPDLLLVMGTSLKAYGIARAVHG-NKPQPRVIFVNETPP--LAEWRKVFDVHISGTTDDWVKLVRE--------
>tr|A0A067NSF8|A0A067NSF8_PLEOS Uncharacterized protein (Fragment) OS=Pleurotus ostreatus PC15 GN=PLEOSDRAFT_1035499 PE=4 SV=1
-----------------------------------AVAKSKKIVVVTGAGISCSCGIPDFRSSDGLYALRDLFDAS----LFRDQRSTAVFYTQLKRSID
--GVAPSRTHRFLKTLDSK-KKLLRSYTQNIDGLEEKAGLVRNVQLHGDIHRVRCVSCSAEYACAEEHLDPPECPECATVGSLRPAIVLYDEPHPLGDDI
GMIQRRPDILIIMGTSLKVHGLAKAVHSAKKMAGKVIFVNKTAP--GSEWADIIDYHVAGETDAWCERVEADWR-----
>tr|A0A0C3FWX6|A0A0C3FWX6_9HOMO Uncharacterized protein OS=Piloderma croceum F 1598 GN=PILCRDRAFT_62275 PE=4 SV=1
-----------------------------------TVAKSKKIVVVTGAGISCSCGIPDFRSSDGLYALRDLFDAS----LFRDPTSTSVFYTKLKQSID
--VASPSPTHRFIKTLDTK-HKLLRSYTQNIDGLEARAGLVKNVQLHGDIHRVRCTFCSAEAPCTEVHLKAPDCPECVTIGTLRPAIVLYDEPHPLGDDI
GTIQRKPDMLIIMGTSLKVHGLAKTVHASKTWTGKVIFVNRTPP--AGEWSDIIDYHVVGDTDTWVDKVIEDWK-----
>tr|M2RTV7|M2RTV7_CERS8 Uncharacterized protein OS=Ceriporiopsis subvermispora (strain B) GN=CERSUDRAFT_147269 PE=4 SV=1
-----------------------------------AVAKCKKIVVVTGAGISCSCGIPDFRSSDGLYALRDLFDAS----LFRNPTSTAVFYTGLKRSID
--SAKPSPTHRFIKTLDSK-RKLLRSYTQNIDGLEERAGLVRNVQLHGDIHRVRCTFCSAEFPCTEEHIVPPDCPECTDVGTLRPSIVLYDEPHPLGDDI
GSIQRKPDMLIIMGTSLKVHGFAKAVRETRSYAGKVVFVNKTAP--GSEWDGIIDYHVEGETDQWAEKVIEDWK-----
>tr|Q5KPC9|Q5KPC9_CRYNJ Hst3 protein, putative OS=Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) GN=CNA03250 PE=4 SV=
-----------------------------------AVAKARRIVTVSGAGISCSSGIPDFRSEGGLYSLKDLFSAG----TFANPQSTSIFYTELFHCCA
--SAQPTRTHHFIRKLEQK-GKLLRSYTQNIDGFERRMGLTRNVELHGDLGRVRCVLCFSDFEACDEWVEAPDCPACWKVGRLRPSIVLYDEPHPLGDDI
GQLTRRPDLLLIMGTSLKVHGLAKAVHG---KRGLVVFVNATPP--SKEWEGIIDVHIEGETDKWVEKVEEEWR-----
>tr|A0A0D0A6S9|A0A0D0A6S9_9HOMO Unplaced genomic scaffold scaffold_3, whole genome shotgun sequence OS=Pisolithus microcarpus 441 GN=PISMIDRAFT_386106 PE=4 SV=
-----------------------------------SVAKCKKIVIVTGAGISCSCGIPDFRSSDGLYALRDLFDAS----LFRDQTSTSVFYTQLKRSID
--SASPAPTHEFIKRLDSK-HKLLRSYTQNIDGLEEKAGLVRNIQLHGDIRRVRCTLCSVDLLCTEEFLCAPDCPECTLIGSLRPAIVLYDEAHPMGDDI
GKIQRKPDMLIVMGTSLKVHGLAKVVHTVKKWQGKVVFVNKTAP--GTEWSELIDYHIMGDVDKWVEKVTEDWR-----
>tr|A0A0C3AYW1|A0A0C3AYW1_9HOMO Uncharacterized protein OS=Scleroderma citrinum Foug A GN=SCLCIDRAFT_102165 PE=4 SV=1
-----------------------------------SVAKCKKIVVVTGAGISCSCGIPDFRSSDGLYALRDLFDAS----LFRDRTSTSVFYTQLKRSID
--SAMPAPTHRFIKTLDSK-RKLLRSYTQNIDGLEERVGLVRNVQLHGDIHRVRCTLCAVDIPCTDEYLSAPDCPECKLIGTLRPAIVLYDETHPLGDDI
GTIQRKPDMLIIMGTSLKVHGLAKAVHAVNKWQGKVVFVNKTAP--GSEWSDVIDYHVMGETDTWVEKVIEDWK-----
>tr|A0A0L0T4X9|A0A0L0T4X9_ALLMA Uncharacterized protein OS=Allomyces macrogynus ATCC 38327 GN=AMAG_14386 PE=4 SV=1
-----------------------------------ALYHAKRIVVVTGAGISVSAGIPDFRSENGLYALQDLFDAA----LFRAEATTRLFYQGLRDATR
--AANPTSTHRFLRHLDER-GSLLRVYTQNIDGLETRAGIPRVVELHGSLDTVRCTRCADQFPFTSRFAAAPACPSCLRTGALRPNVVLYNETHPAGDEI
ADAVKRPDVLVVMGTSLKVHGIAAAIHDRKKKHGLVILVNRTLP--AKEWGEVFDVVLTGDADDVVHHRLRSWG-----
>tr|A0A067MQ39|A0A067MQ39_9HOMO Uncharacterized protein OS=Botryobasidium botryosum FD-172 SS1 GN=BOTBODRAFT_105485 PE=4 SV=1
-----------------------------------AVARSKRIIVITGAGISCSSGIPDFRSSDGLYNMRDLFDAS----LFRDPTSTQLFYTELKASID
--AATPSPTHRFIKTLHTK-GKLLRSYTQNIDGLEEQAGLIKSVQLHGDIHRVRCTICSAEYRCEQHHVEPPSCPDCSVVGTLRPSIVLYEEVHPLGDEI
GTISRRPDLLIIMGTSLKVHGIASAVHNVNPFSRKVVFINRTPP--AGEWEGVIDYWVKSDTDPWVQKCEEDWK-----
>tr|A0A0C9XV99|A0A0C9XV99_9AGAR Unplaced genomic scaffold K443scaffold_5, whole genome shotgun sequence OS=Laccaria amethystina LaAM-08-1 GN=K443DRAFT_84095 PE
-----------------------------------SVAKSKKIVVVTGAGISCSCGIPDFRSSDGLYALRDLFDAS----LFRDATSTSVFYTQLKRSID
--AATPSPTHEFIKTLDAK-KKLLRSYTQNIDGLEARVGLVRNVELHGNIHRVRCMACSAEYPCTEDHLNPPDCPECLSVGSLRPAIVLYDEPHPLGDDI
GTIQRKPDMLIIMGTSLKVHGLARTIHA---RPFKVIFVNKTPP--ASEWADVIDYHIAAESDRWVTKVLEDWK-----
>tr|A0A0D2MPI7|A0A0D2MPI7_9AGAR Uncharacterized protein (Fragment) OS=Hypholoma sublateritium FD-334 SS-4 GN=HYPSUDRAFT_160442 PE=4 SV=1
-----------------------------------SIAKRKKIVVVTGAGISCSCGIPDFRSSDGLYALRDLFDAA----LFRDPTSTAVFYTQLKRSID
--AAEPAPTHHFIKTLDTK-KKLLRSYTQNIDGLEARVGLIRNVQLHGDIHRVRCIACSADYPCSEEYLQAPECPECLSVGSLRPGIVLYDETHPLSDDI
GSIHKKPDMLIIMGTSLKVHGLARSIHSGSKKPCKVIFVNKTAP--GSEWSDIIDCHISGETDAWTTKVIEDWK-----
>tr|A4VJ26|A4VJ26_PSEU5 Uncharacterized protein OS=Pseudomonas stutzeri (strain A1501) GN=PST_1283 PE=4 SV=1
-----------------------------------ALAAAERLLIITGAGLSADSGLPTYRGPGGLYNGATDDGVASGPTLQRQPALCWKYLAEIGRACL
--RAEPNAGHFAIAEWQRQRPGTWL-LTQNIDGFHRRAGSERLIEIHGELAPLSCMACGEIDRRPLDEPLPPRCEVCT--GVLRPAVVLFEEMLPE--RA
LARLQGFDAVLVVGTTAS----FGYILEARQSGGLVVEVNLQPTDISPLANLSLQGRAADVLSHLLR------------
>tr|A0A074YV69|A0A074YV69_9PEZI Uncharacterized protein OS=Aureobasidium subglaciale EXF-2481 GN=AUEXF2481DRAFT_44820 PE=4 SV=1
-----------------------------------LIQKSNKIMVITGAGISTSLGIPDFRSTNGFYSKLRLLGHSNPENFDEDPTT---FYTLAKDILP
-MTGKCSPTHAFIRLLQDK-QKLLTNYTQNIDNIEAYAGIEKLIQCHGSWATASCRKCKVEVPGFEDVRQVSYCQACLDPGVMKPNITFFGELPTRFDRL
THDAAIVDLIIVIGTSMKVAPVSNYVD----EKVPQIYISKEAAD-HINFDITLLGYCDDVV-----------------
>tr|A0A074XCA4|A0A074XCA4_AURPU SIR2-domain-containing protein OS=Aureobasidium pullulans EXF-150 GN=M438DRAFT_375537 PE=4 SV=1
-----------------------------------LLQKSKNIMVITGAGISTSLGIPDFRSKNGFYSKLLARGFDSPENFDEDPTH---FYELAHDILP
-VTDRCSPTHAFIKLLQDK-QKLLTNYTQNIDNIEEYAGIERLIQCHGSWATASCRKCHTEVKGFEDVRQVSLCKTCLDPGVMKPNITFFGELPSRFDRL
THDVAMVDLIVVIGTSMKVAPVSNFVD----EKVPQIYISREPAD-HINFDITLLGYCDDVV-----------------
>tr|R7YHB0|R7YHB0_CONA1 Uncharacterized protein OS=Coniosporium apollinis (strain CBS 100218) GN=W97_00391 PE=4 SV=1
-----------------------------------LLRKSKNIMIIAGAGISTSLGIPDFRSKNGFYSKLQDHGFDDPENFDEDPTI---FYSLAGDIIP
-DLRTWSPTHEFIRLVQEK-GKLLTNYTQNIDNLESHAGIEKLVQCHGSWATATCRKCKYRVPGFDDVRAVAVCKRCVEPG---PDITFFGELPEKFERI
RHDRELVDLVIVIGTTLKVAPVSQFIS----PEVPQIFISRDPIH-HINFDINLLGDCDTIV-----------------
>tr|S9RAB8|S9RAB8_SCHOY Sir2 family histone deacetylase Sir2 OS=Schizosaccharomyces octosporus (strain yFS286) GN=SOCG_01287 PE=4 SV=1
-----------------------------------QLHKAKNIVVLVGAGISTSLGILDFRSDNGFYSRLAQHGLSEPSTFREEPGI---FYTFAKELLP
-ETQHYSPSHAFIRLLEQK-NKLSTLFTQNIDNLERETGLEKVIQCHGSFATATCIQCKHKVEGYDDIRNISYCTECNQAGVMKPDITFFGELPDQFEKV
GGDLEKTDLLICIGTSLKVAPVSSLVP----ASTPQLYISRTPVR-HTQFDVNFISPCDWVI-----------------
>tr|B6K658|B6K658_SCHJY Sir2 family histone deacetylase Sir2 OS=Schizosaccharomyces japonicus (strain yFS275 / FY16936) GN=SJAG_04186 PE=4 SV=1
-----------------------------------LIQSCDNIIVLTGAGISTSLGIPDFRSDDGFYAKLAEHGLSEPMVFREDPSI---FYKFAREILP
-QTTQFSPTHAFIRLLEKK-GKLNTLFTQNIDNLEHYAGIDKTVQCHGSFAKATCVQCRYEIDGYEDIRKVPRCSKCGQPGVFKPNITFFGELPETFAKI
GEELRKCDLLICIGTSLKVAPVSGLLP----PTTPQVYISRTQLR-HTQFDVSLLSPSDWVV-----------------
>sp|O94640|SIR2_SCHPO NAD-dependent histone deacetylase sir2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=sir2 PE=1 SV=2
-----------------------------------LLKKAKNVVVLVGAGISTSLGILDFRSDNGFYARLARHGLSEPSTFRENPEI---FYTFARDLLP
-ETNHYSPSHAFIRLLEKK-NKLSTLFTQNIDNLEKKTGLNKIIQCHGSFATATCIKCKHKVDGYEDIRNVSYCNECGKPGIMKPDITFFGELPDSFNKV
GGELEETDLLICIGTSLKVAPVSSVIP----PTTPQIYISRTPVR-HTQFDVNFLSPCDWVI-----------------
>tr|S8ACU1|S8ACU1_DACHA Uncharacterized protein OS=Dactylellina haptotyla (strain CBS 200.50) GN=H072_5362 PE=4 SV=1
-----------------------------------LINKSSNIMVLTGAGISTSLGIPDFRSKGGLYSRLEGLGLSDPQIFKEDPSI---FYSIAKDILP
-TTNKFSPTHAFIELLQRK-GKLLRNYTQNIDNIEHLAGVEKLVQCHGSFATASCVKCKFQVSGFEDLRAIAKCPKCVEIGVMKPDIIFFGELPDRFHRI
VHDRAKVDLLICIGTSLKVAPVSAFLP----ANVPQIYISREPVH-HIEFDVELIGDCDDIV-----------------
>tr|E4ZMI6|E4ZMI6_LEPMJ Putative uncharacterized protein OS=Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8) GN=LEMA_P055610.
-----------------------------------LLRERKNIMVITGAGISTSLGIPDFRSKNGFYSRLLQMGYDEPENFDQDPRT---FYALAGDIIP
-DLEKWTPTHEFIRLLQDK-DKLLTNYTQNIDNVEAHAGIDKLIQCHGSWATATCRKCKFKVPGFDSVRAPAECKRCMDPGIMKPDITFFGELPNDFDRL
KIDKDLVDLVIVMGTSMKVAPVSNFLP----RDVPQIYISRDPIY-HINFDINLLGDCDVVV-----------------
>tr|A0A0D2B623|A0A0D2B623_9PEZI Uncharacterized protein OS=Verruconis gallopava GN=PV09_02389 PE=4 SV=1
-----------------------------------LLNASKKIMVVTGAGVSTSLGIPDFRSKSGFYSKLQARGFQEPETFDEDPSL---FYSLAGDILP
-DLNKWTPTHQFIRIIQDK-GKLLRNYTQNIDNIESHAGISKLIQCHGSWAHATCRKCGYKVPGFENIRAVATCKRCEQPGVMKPDITFFGELPDLFDTL
QHDRNEVDLVIVMGTSMKVAPVSNYLP----ANVPQIYISRDPVY-HINFDINLLGDCDTIV-----------------
>tr|R1GY03|R1GY03_BOTPV Putative histone deacetylase protein OS=Botryosphaeria parva (strain UCR-NP2) GN=UCRNP2_2286 PE=4 SV=1
-----------------------------------LLQKSKNIMVITGAGISTSLGIPDFRSKNGFYSKLREMGFEDPENFDEDPTI---FYKLAGDILP
-DLYNWTPTHEFIHLLQEK-GKLLTNYTQNIDNLESHAGIEKLVQCHGSWATATCRECGHQIPGFQNIREVAECQECVRPGVMKPDITFFGELPSRFTRL
RHDKDVVDLVIVIGTSMKVAPVSQILR----PNVPQIYISRDPIR-HIDFDVNLLGDCDVVV-----------------
>tr|A0A066VI74|A0A066VI74_9BASI SIR2-domain-containing protein OS=Tilletiaria anomala UBC 951 GN=K437DRAFT_239109 PE=4 SV=1
-----------------------------------LIKTARNIVVLTGAGISVSCGIPDFRSRDGIYASL--AGLDEPEYFMQQPSV---FFDFAHSIFP
-SNFKPSPSHRFIKLLEDK-EKLLRNYTQNIDTLEKAAGITRVLHCHGSFATATCTACRHKVQGKDAIFKVPQCRVCQKLGVMKPDITFFGELDSSFENA
LADRPHADLIIVMGTSLQVAPVATYMP----HRIPVILINKTPIL-HFQTDIMLLGSSDQVV-----------------
>tr|A0A0M9VQ19|A0A0M9VQ19_9BASI Sir2-domain-containing protein OS=Malassezia pachydermatis GN=Malapachy_0931 PE=4 SV=1
-----------------------------------LLTKSKKIVVLCGAGISVSCGIPDFRSKDGIYAILAAEDLDDPSTFLRDPSL---FFSFAHSIYP
-ANYEPSPSHRFVRMLEQR-GKLLRMYSQNIDTLEQKAGIERVIQCHGSFSTATCTQCGYHVDGREDIMAVPLCPRCEKYGVMKPDITFFGELPDAFEKC
VADRNEVDLILVMGTSLKVAPVARHLP----SSVPTVLINRTPIT-HMATDVMLLGDSDPIV-----------------
>tr|A0A0K6FWR2|A0A0K6FWR2_9HOMO NAD-dependent histone deacetylase SIR2 OS=Rhizoctonia solani GN=Sir2 PE=4 SV=1
-----------------------------------LIKRSKNIVVLTGAGISVSCGIPDFRSSSGIYAQINENNLEDPQYFREKPSV---FYSFASQIYP
-SNFIPSPCHRFIRLLEDK-DILLRNYTQNIDTLETEVGVTRVLQCHGSFATATCIECKTKVNGKDDIFAIPLCKTCNKKGIMKPDIVFFGELNDEFDHC
LKDRESVDLLLVIGTSLKVAPVSTHIP----HSVPQVFINKTPVT-HVNPDVVLLGDADRVI-----------------
>tr|M5GC32|M5GC32_DACSP SIR2-domain-containing protein OS=Dacryopinax sp. (strain DJM 731) GN=DACRYDRAFT_21165 PE=4 SV=1
-----------------------------------LIRNSKHILVLTGAGISVSCGIPDFRSTQGIYAQLRESELADPQFFKENPSV---FYSFAHRIFP
-SNFKPSPCHYFIKLLEDK-SKLLRNYTQNIDTLETVAGVKKVLNCHGSFATASCITCGTQFPGKEDIFAIPKCTVCIGKSILKPDITFFGELTSRFDKA
LEDREEVDLLLVIGTSLTVAPVSHHIP----HSIPQIIINKTPVP-HVNPDIVILGEADEAV-----------------
>tr|M9LUE5|M9LUE5_PSEA3 TRAPP 20 K subunit OS=Pseudozyma antarctica (strain T-34) GN=PANT_7d00291 PE=4 SV=1
-----------------------------------LLQRSKRIMVLSGAGISVSCGIPDFRSKDGIYSQLQSEGLDDPQYFLHNPAM---FYSFAHRIFP
-SNFVPSSAHRFIKLLEDR-DQLLRNYSQNIDTLEQLAGIERVLQCHGSFATASCTTCGYKCNGAKDIFAVPACPACEEFGILKPNITFFGELSDDFDRA
LADREHVDLLVVMGTSLKVAPVSGHIP----HTTPVILINKTPIL-HMATDIMLLGDCDHIV-----------------
>tr|A0A077QZH6|A0A077QZH6_9BASI Related to HST1-silencing protein OS=Melanopsichium pennsylvanicum 4 PE=4 SV=1
-----------------------------------LLATRKKIMVLSGAGISVSCGIPDFRSKDGIYSQLQHEGLDDPQYFLANPAM---FYSFAHRIFP
-SNFVPSSAHRFIKLIEDQ-GKLLRNYSQNIDTLEQIAGIEKVLQCHGSFATASCTDCGYRCKGAKAIFDVPQCPKCQEFGILKPDITFFGELSDTFDHA
LADREHVDLLIVMGTSLKVAPVSGQIP----HSTPVILINKTPIL-HMATDIMLLGDCDRIV-----------------
>tr|A0A0P1BL11|A0A0P1BL11_9BASI Sirtuin 5 and related class III sirtuins (SIR2 family) OS=Ceraceosorus bombacis PE=4 SV=1
-----------------------------------LLANARRVVVLSGAGISVSCGIPDFRSRDGIYANLLREGLADPQFFMQDPSC---FFSFANSIFP
-SNFVPSPTHRFIKLLEDR-NVLLRNYSQNIDTLEQQAGITRVLNCHGSFARATCTACGYSVDGRPDIFAVPFCPKCHAWGVLKPCITFFGELSDDFDRC
LQDRESVDLILVMGTSLKVAPVSGHMP----HRVPVVLINRTPIR-HMAVDIQLLGDADLIV-----------------
>tr|I2G6X4|I2G6X4_USTH4 Related to HST1-silencing protein OS=Ustilago hordei (strain Uh4875-4) GN=UHOR_01455 PE=4 SV=1
-----------------------------------LLQRSKRIVVLSGAGISVSCGIPDFRSKDGIYSQLQSEGLDDPQYFLSNPEM---FYSFAHRIFP
-SNFVPSSAHRFIKLIEGR-GQLLRNYSQNIDTLEQLAGIEKALQCHGSFATASCTECGYKCKGAKAIFSVPVCPACEEFGVLKPDITFFGELSDAFDHA
LADREEVDLLIVMGTSLKVAPVSGHIP----HSTPVILINKTPVL-HMATDIMLLGDCDRIV-----------------
>tr|A0DQW0|A0DQW0_PARTE Uncharacterized protein OS=Paramecium tetraurelia GN=GSPATT00002827001 PE=4 SV=1
----------------------------------------KNVLILCGAGLSHASGVPTFRGKDGYWTKFECQKVLTKEFLTSNPDLCW----EWHKDFQ
KMNKKPNAGHIAIANYKKKNPN-TLIVSQNIDNILTSIHYESIYEIHGNIKYMRCSKCTILYDM-PDLTLRPKCPKCG--EDARPHILFFDESYTRIQEL
QEKYETYDTIIVVGTMLETGCAKSTVCKFIKKKAIIIEINPEPIEVGNTYQ--IKGKSEEILPKLL-------------
>tr|A0BIG1|A0BIG1_PARTE Uncharacterized protein OS=Paramecium tetraurelia GN=GSPATT00004700001 PE=4 SV=1
----------------------------------------KNTVILCGAGLSKASGIPTSKEQNGEWIKYPLSKLKTRDFLVDNPKVYW----EWHKQYK
QLDKIPNAGHLAIKNFKEKNKD-ALIVNLSIDNLLASVYNKQIYEINGNIKYMRCLYCTTVYDI-PDLEEIPKCPICG--SKGRPHLLLLDDEILRITEI
QELSQKYETIIVIGTTLQTHFAKTMVCEFIKKKATIIEINPEPVEVGNTFW--LIGKSEEILPELL-------------
>tr|J9ILR0|J9ILR0_9SPIT NAD-dependent deacetylase OS=Oxytricha trifallax GN=OXYTRI_22650 PE=4 SV=1
----------------------------------------KAIMILTGAGLSAASGIPTFRGDNGFWTKYSDMEILTTKTLINDPQVQW----QWRYDFT
DIKCKPNAGHQAIYEFSWQNPTKTQLVTQNIDNFHIDIFVDEVHEIHGNNKYMKCFKCNEPPMD-PDERKVPICYQCG--GVMKSTTMLFDETYSRSETV
SSFQDKLDGLIVVGTALQTNFASHIVMKTLAQNIPVIEVNTEPCTTGYTFQ--VKESSLTALPAMV-------------
>tr|A0A0C3GFL4|A0A0C3GFL4_9HOMO Uncharacterized protein OS=Piloderma croceum F 1598 GN=PILCRDRAFT_225362 PE=4 SV=1
-----------------------------------QSKTCRNVFLMLGAGISTAAGIPDFRSPDGLYANLARLNLPYPEFFRRHP---EPFYMLA-KELY
PGKFRPTLTHSFVRLLASK-SLLHTCFTQNIDTLERRAGVGKIIEAHGSFATQRCIECKRPYDKMKKAVKIPRCEKE--RGLVKPDIVFFGELPDEFHRA
IPTLREADLLIVMGTSLTVRPFAMLAELVR-EGCLRVLINLEKVGLGDEDDIVCLGKCDEIVQELAREL----------
>tr|A0A0C2STN5|A0A0C2STN5_AMAMU Uncharacterized protein (Fragment) OS=Amanita muscaria Koide BX008 GN=M378DRAFT_56865 PE=4 SV=1
-----------------------------------KTDRCRNIIFMLGAGVSTSAGIPDFRSPDGTCANLHHLNLPTPEFFKHNP---KPFYVLA-KELR
PGKFRPTLTHSFVRLIHEK-GLLLKCFTQNIDTLERRAGIDKLVEAHGSFASQRCIKCKRPYDKMAEAFEFATCPKC--HGLVKPDIVFFGELPARFVGS
LDNFPEADLLIIIGTSLTVFPFARLVEFTR-SNCPRVFINLERVMFNQGDDVVLLGKCDAIIEQLCKEL----------
>tr|A0A067MJH6|A0A067MJH6_9HOMO Uncharacterized protein OS=Botryobasidium botryosum FD-172 SS1 GN=BOTBODRAFT_34903 PE=4 SV=1
-----------------------------------KSGKCKNVFIMAGAGISTAAGIPDFRSPDGIYSNLEKLGLPNPEYFRIKP---EPFYELA-RELA
PGKFKPTLTHAFIRLLHEK-SLLHTCFTQNIDTLERRAGVDKLVEAHGSFATQRCIDCREPYPDMADAIRVPVCLSC--GGLVKPDIVFFGELPPNFHSA
LPALQTASLAIVLGTSLKVRPFALLPEMVP-ETSPRLLINLDHVGFGSTDDVIVLAKCDEGVIMLCREL----------
>tr|A0A066WLA5|A0A066WLA5_9BASI NAD-dependent deacetylase sirtuin-2 OS=Tilletiaria anomala UBC 951 GN=K437DRAFT_244502 PE=4 SV=1
-----------------------------------QKGKAKQILVMTGAGTSTSAGIPDFRSPDGLYANLQKYNLPYPEFFHEKP---EPFFTLA-KELF
PGNYKPTLTHVFFRLLHEK-QKLLRVFTQNIDTLERAAGLEAIVEAHGSFASSKCTKCKTAVSDMRASIMVVRCE----GGLVKPDIVFFGELPDRFFQR
LSDFQKADLLLVLGTSLQVQPFASLIDKVPD-ECPRMLINLERVGLANARDVLYEGKCDDGVLELAMA-----------
>tr|N1JHX2|N1JHX2_BLUG1 Uncharacterized protein OS=Blumeria graminis f. sp. hordei (strain DH14) GN=BGHDH14_bgh00253 PE=4 SV=1
-----------------------------------LANRIQHIVVMTGAGISTSAGIPDFRSPGGLYANLDSLDLPDAEYFRENP---VPFYTLA-KELN
PGKFYPTLSHCFITLLNEK-ALLSMLFTQNIDCLERKAGIEKIVEAHGSFATQRCIDCKTQFPLMQVAIEVPYCLQC--NGLVKPDIVFFGELPLSFFLN
RSSISQADLVIVMGTSLSVQPFASLPAGAD-IEVPRVLINNAVVGFGSPNDVMIIGDCDAGVLELAEAL----------
>tr|A0A0H2SCM6|A0A0H2SCM6_9HOMO NAD-dependent deacetylase sirtuin-2 OS=Schizopora paradoxa GN=SCHPADRAFT_927647 PE=4 SV=1
-----------------------------------KSDACKNIFIMAGAGISTSAGIPDFRSPDGLYANLARLKLPYPEFFRNNP---KPFYTLA-HELA
PGKFRPTLTHSFIRLLAEK-NYLHTCFTQNIDTLERRAGVDKIIEAHGSFATQHCIKCKAEYPEMREKIKLPICNKC--KGYVKPDIVFFGELPDEFFSS
LEHLRSADLLIVMGTSLTVHPFASLTEIVD-ESCPRLLLNLDLVGWGSTNDVSCLMPCDDAVRKICELL----------
>tr|A0A060T3A6|A0A060T3A6_BLAAD ARAD1C35750p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1C35750g PE=4 SV=1
-----------------------------------ANGEFKRVVFMVGAGVSTAAGIPDFRSPEGLYANLARLKLPYPEYFRKRP---EAFYTLA-DELY
PGKFEPTKFHSFMKVVQDH-GCLLRVFTQNIDTLEHLAGVDKIVAAHGSFANNHCIECRRAMSRLKQIMWVPKCEKC--GGLIKPDIVFFGELPRRFFDL
SD-VDVDDLVIVAGTSLTVMPFAQLPDMVP-DETIRVLFNMEQVGFGDENDVVVLGDCDDNIAKFADMA----------
>tr|A0A0K3CNL7|A0A0K3CNL7_RHOTO BY PROTMAP: gi|472584949|gb|EMS22524.1| NAD-dependent deacetylase sirtuin 2 [Rhodosporidium toruloides NP11] gi|647400915|emb|C
-----------------------------------KDGKAKRIMLMVGAGVSTGAGIPDFRSPGGLYDNLA-------KYLEERP---EAFYTLA-QELY
PGNFRPTLSHYFFRLLQEK-GVLRGCWTQNIDTLEHLAGLELLVEAHGSFATATCLNCRTKFDDIKPRVLVVRHD----RALIKPDIVFFGELPDKFFER
LSDFSSCDLLIVIGTSLQVGPFNSLMHRVPA-TCPRLLINMESVGVESIRDVRRLGDADEGIMELARLI----------
>tr|A0A081CBY0|A0A081CBY0_CANAR NAD-dependent deacetylase sirtuin 2 homolog OS=Candida antarctica GN=PAN0_004c2386 PE=4 SV=1
-----------------------------------ASPATRNVVVLAGAGISTSPPIPDFRSPGGLYSNLAQYNLPYAEYFQRKP---QPFFTLA-KHLY
PGNFKPALAHYFLAQLQAR-NKLLRVFTQNVDTLERIAGVERIVEAHGSFATSTCIACKHRVDWIRTKVEVARCP----GGLVKPDIVFFGELPSRFFRC
IPDLKKADLLIVMGTSLQVQPFASLIDAVPA-DCPRVLLNLEKVGIASTRDVFWQGKADDAVQKLTQLM----------
>tr|E6ZUM4|E6ZUM4_SPORE Related to NAD-dependent histone deacetylase OS=Sporisorium reilianum (strain SRZ2) GN=sr16510 PE=4 SV=1
-----------------------------------AQPTTRNVVVLAGAGISTSPPIPDFRSPGGLYSNLAAYNLPYAEYFQRHP---QPFFTLA-KHLY
PGNFKPALAHYFLALLQAR-GKLKRVFTQNVDTLERIAGVDRVVEAHGSFATSTCIACKHRVDWIRARVEVARCPEA--GALVKPDIVFFGELPSRFFRC
IPDLQSADLLIVMGTSLQVQPFASLIDAVPSPTCPRVLINLERVGLASTRDVFYEGKADDGVAELVKLV----------
>tr|R9PBU7|R9PBU7_PSEHS Class I sirtuins SIR2 OS=Pseudozyma hubeiensis (strain SY62) GN=PHSY_006468 PE=4 SV=1
-----------------------------------ASPSTRNVVVLAGAGISTSPPIPDFRSPTGLYSNLAAYNLPYAEYFQKHP---QPFFTLA-KHLY
PGNFKPALAHYFLTLLQQK-GKLKRVFTQNVDTLERIAGVDKVVEAHGSFATSTCIVCKQRVEWIREKVMIARCPQE--GGLVKPDIVFFGELPARFFRC
IPDLKSADLLIVMGTSLQVQPFASLIDAVPE-TCPRVLINLERVGLASTRDVFYQGKADDGVAELVRLV----------
>tr|I2FXL2|I2FXL2_USTH4 Related to NAD-dependent histone deacetylase OS=Ustilago hordei (strain Uh4875-4) GN=UHOR_08392 PE=4 SV=1
-----------------------------------AQPTTRNVIVLAGAGISTSPPIPDFRSPGGLYCNLAACNLPYAEYFQRHP---QPFFTLA-KHLY
PGNFKPALAHYFLALLQNK-GKLKRVFTQNVDTLERIAGVDKIVEAHGSFATSTCIVCKHRVDWIRAKVMVARCPDG--EGLVKPDIVFFGELPSTFFRC
MPDFKMADLLIVMGTSLQVQPFASLIDAVSA-SCPRVLINLERVGWASTRDVFYEGKADDGVAELVKLV----------
>tr|A0A077RDV3|A0A077RDV3_9BASI Related to NAD-dependent histone deacetylase OS=Melanopsichium pennsylvanicum 4 PE=4 SV=1
-----------------------------------SAPTTRNIIILAGAGISTSPPIPDFRSPGGLYSNLASYNLPYAEYFQRHP---QPFFTLA-KHLY
PGNFKPALAHYFLTLLQSK-GKLKRVFTQNVDTLERIAGVDKVVEAHGSFASSTCIVCKHRVDWIRAKVEVARCPGV--GGLVKPDIVFFGELPSRFFTC
IPDLKTADLLIVMGTSLQVQPFASLIDAVPQ-HCPRVLINLERVGLASTRDVFYEGKADDGIIELVKLI----------
>tr|A0A060SRF0|A0A060SRF0_PYCCI Uncharacterized protein OS=Pycnoporus cinnabarinus GN=BN946_scf184657.g7 PE=4 SV=1
-----------------------------------KSPQCRRVFVMLK--LEAGS-WREYGGRHGLSSNLQRLNLPYPEYFRENP---VPFYTLA-RELY
PGRFRPTLTHTFVKLLSDH-SLLDTCFTQNIDTLERLAGVDKIVEAHGSFASQHCIECHASVDQMRKAVEIVRCGEC--GGLVKPDIVFFGELPPAFHKS
VPRLRSADLLIVIGTSLTVQPFASLTALVP-EGCPRVLINMDPAGIGTPDDVVLLGRCDEIVRDLCREL----------
>tr|K5VS10|K5VS10_PHACS Uncharacterized protein OS=Phanerochaete carnosa (strain HHB-10118-sp) GN=PHACADRAFT_131245 PE=4 SV=1
-----------------------------------KSDKCKNIFVMVR--VSTSAGIPDFRSPGGMSSNLQRLNLPHPEFFRENP---VPFYTLA-KELF
PGRYRPTPTHSFVRVLHNR-KLLGMCFTQNIDTLERLAGVSAVVEAHGSFADQHCIECGSWYDKLRDQILIAYCNEC--GGLIKPDIVFFGELPPRFHKT
IGLLRTADLLIVMGTSLTVHPFASLTRMVP-EGCPRVLVNMTSAGIGTADDVTLLGRTDEVVRELCEAL----------
>tr|M5FZZ2|M5FZZ2_DACSP NAD-dependent deacetylase sirtuin-2 OS=Dacryopinax sp. (strain DJM 731) GN=DACRYDRAFT_24170 PE=4 SV=1
-----------------------------------KSEQCRKVYIMAGAGISTSAGIPDFRSPEGLYHNLQRLNLPYAEYFRENP---IPFYTLA-KDMD
PSKFRPTLTHSFFKLMDEK-GLLNMCFTQNIDTLERRAGLEKIIEAHGSFASNSCIECKMPFDEMSEAVEPARCDSC--GGLVKPDIVFFGELPSSFFST
VPELRSADLLFILGTSLTVMPFAGICRLVP-ESCPRVLINLDAVGIGSPDDVLALGECDTVVRKLCEEL----------
>tr|A0A085W9Q2|A0A085W9Q2_9DELT NAD-dependent protein deacetylase of SIR2 family protein OS=Hyalangium minutum GN=DB31_2209 PE=4 SV=1
-------------------------------------SEARSVLALTGSGISVGSGLATR---KELWQRWDRDAAVSVFRFREDPGVLWKVI---ADFLG
TGPHAPAPGHLALAECPNLI----GIVTQNVDGLHQAAHMPSVIELHGTLLETRCHTCHSRTGREAPRAHPPLCESCG--GPLRPDVVLFGERVERMLEA
IQLVQRCDVLLVVGTAMDVAPAADLPRVARARGAVVIELKRTPSLLSRSLDTLVPGEADVVLPALMSA-----------
>tr|A0A0N8R969|A0A0N8R969_PSESX NAD-dependent protein deacetylase OS=Pseudomonas syringae pv. cunninghamiae GN=ALO74_04799 PE=4 SV=1
----------------------------------CETMTDKSFLVVTGAGISTASGIPDYRDKDGVRRGKQ---PMMYQEFVGNPAARQRYWA--RAMLG
WPRIQANAAHRALAALQVENSI-SGLITQNVDALHSQAGSQDVIELHGCLHRVLCLDCQQRSERADDLDPVPRCPHCDG-DRLKPDVVFFGENPQTAAKA
TTSVEQAEGLLVVGTSLMAWSAFRLCKAMVEQGKPVFAINHGKTRADELLEMKIDASCEQVLP-WIAEQL---------
>tr|F4Q2K8|F4Q2K8_DICFS Ankyrin repeat-containing protein OS=Dictyostelium fasciculatum (strain SH3) GN=sir2B PE=4 SV=1
----------------------------------IRQGKIKNIVLLTGAGISTNAGIPAYRTEDGIYNRNKQFSFS-MQSIQEQPT---VFFESIKNPVV
TGQIPPTKTHEFIFDLYEK---NVLLFTQNVDGLDEMVGLDKIVHAHGSLRSWRCSNCQQAVPQELVNEQIPYCQKCQQQSILRPDVIFFGELPVRYQQS
IKDLRKCDLLIIIGTSLSVYPFASLVNDVQSHVP-RILINKGPFRGVSDFDRSN-------------------------
>sp|Q55DB0|SIR2E_DICDI NAD-dependent deacetylase sir2E OS=Dictyostelium discoideum GN=sir2E PE=2 SV=2
--------------------------------LAKEMLSGKKILFITGAGLSINSGISAYRNTTSVWSNF-ITEWGTRKKFEQDPAQFWNHFWLRTHEKQ
ELDALPNSGHLAISNFVEYLG--SNVITQNVDALHLKAKVEKLVEVHGRISLYKCITKGCRFEYDDTIDNPPLCPECKK--PILPQSLLFDENFYNIEKA
MDWIQEADIFIFIGTSFSVGITEEVICHAQSERKKMFNFNIFKETKIS-GLKSIVGKSEITLPLLERQLLYE-------
>tr|V6M1S7|V6M1S7_9EUKA NAD-dependent deacytelase Sir2 OS=Spironucleus salmonicida GN=SS50377_12665 PE=4 SV=1
--------------------------------LVDILISGQTVVFLTGAGLSVSSGITPYRYSQAIWSKF-IQDQGTRKQFKRDPASYWNDFWLRTHEKS
ELKAKPNPGHFAISAILRLCN--TRIVTQNIDTLHTKAGVDRLAEVHGSLGKYKCINNRCQIATSKYASIPPRCPICQA--PMMPLTLMFDENMFGYSKA
ERWFQKAAAIVFVGTSLSVRITSDAVRLSERNKAQYFNFNVMDDDRVQ-NQKWVLGKAENTLEQVRTILIEK-------
>tr|L8GES9|L8GES9_ACACA Transcriptional regulator, sir2 family OS=Acanthamoeba castellanii str. Neff GN=ACA1_389540 PE=4 SV=1
--------------------------------LVADLCNGEVPLFITGAGLSAASGIAPYRGTTAVWTNF-VMSWGTRSKFKKNPTLWYNKFWLRTHQKP
EFKAQPNAGHYAIAAISQMCA---------------KTALHKLIEVHGRLGMYKCY------AYDESIDDAPICPSCDE--AVLPQALLFDEQFYQWDRV
DEWFHDSDVLIFVGTSFSVGVTEKALAIAQEFGKKVYSFNLYAERREDYWIQHILGPSEKTLPTLAHRMQHY-------
>tr|D2A3P1|D2A3P1_TRICA Putative uncharacterized protein GLEAN_14968 OS=Tribolium castaneum GN=GLEAN_14968 PE=4 SV=1
-------------------------------------DDYDKILVLTGAGISTESGIPDYRSEDGLYANHRP--V-QYQEFLKSEKVRQRYWA--RNYIG
WPQTQPNITHYIVQFLESV-GKVGCVVTQNVDSLHFKAGSGNVIELHGTAFRVICLKCGKNYDRHPDLREPPFCDHCQ--GVLKPDITFFGDVPKRVDKV
RQNVTQSDAILVLGSSLSVFSGYRIILQAVEEKKDVAIVNIGPTRADKHKISARYGL---IVPN---------------
>tr|M5BRQ0|M5BRQ0_THACB NAD-dependent histone deacetylase SIR2 OS=Thanatephorus cucumeris (strain AG1-IB / isolate 7/3/14) GN=BN14_04467 PE=4 SV=1
-----------------------------------LIKKSKNIVVLTGAGISVSCGIPDFRSSSGIYAQIN--ENNNYE--LEDPQQMFDYFREKPSQIY
PSNFVPSPCHRFIRLLEDR-DILLRNYTQNIDTLETEVGVTRVLQCHGSFATATCIECKTKVNGKEDIFAIPLCKNCNKKGIMKPDIVFFGELNDEFDHC
FKDRDSVDLLLVIGTSLKA-GF----SEILTHSVPQVLINKTPVT-HVNPDVVLLGDADRVIEYLCDKL----------
>tr|F8Q9G1|F8Q9G1_SERL3 Putative uncharacterized protein OS=Serpula lacrymans var. lacrymans (strain S7.3) GN=SERLA73DRAFT_95897 PE=4 SV=1
-----------------------------------LITSSRRILVLTGAGISVSCGIPDFRSRDGLYATLK--ERGEYE--LDDPQQMQSYFNI-HSPIP
PLRINSLMATIFASCIAPT-SMFLINYTQNIDTLETLAGISRVLQCHGSFKTASCLQCRHKVPGEKDILEVPYCDVCVAVGVMKPDITFFGELTDEFDHA
VEDRDKVDLLLVIGTSLKVSPV----SEIISHSVPQILINKTPIR-HINPDIVLLGNADEIVHHLCEQI----------
>tr|A0A0C3AU79|A0A0C3AU79_9HOMO Uncharacterized protein (Fragment) OS=Serendipita vermifera MAFF 305830 GN=M408DRAFT_78366 PE=4 SV=1
-----------------------------------LLQSAQRVMVLTGAGISVACGIPDFRSSDGIYARIK--ASGQYED-LDDPQEMYAYYETQLSQLW
PKDVQPSVSHKFIRLLEAK-NKLLRNYTQNIDSMESIAGVERVFYCHGSFATAKCMDCQNEVTGHDDVVQVPRCPPCVKAGVMKPGITFFGELSDNFDNL
YVDREEVDLLLIIGTSLKVKPV----SEILAHSVPQILINKTPVE-HVNPDIVLLGDCERIIEYLCDGL----------
>tr|A0A074VLK9|A0A074VLK9_9PEZI SIR2-domain-containing protein (Fragment) OS=Aureobasidium melanogenum CBS 110374 GN=M437DRAFT_59169 PE=4 SV=1
-----------------------------------LLQKSKNIMVITGAGISTSLGIPDFRSRTGFYSQLL--ARG-----FESPEDVFD----DPKEIL
PVTDRCSPTHAFIRLLQDK-QKLLTNYTQNIDNIEAFAGIERLIQCHGSWATASCRKCQTEVPGFEDVRQVSLCQNCLDPGVMKPNITFFGELPNRFDRL
EHDAAIVDLIIVIGTSMKVAPV----SEIPNYKVPQIYISREPAD-HINFDITLLGYCDDVVAELAKRA----------
>tr|N1Q796|N1Q796_PSEFD Uncharacterized protein OS=Pseudocercospora fijiensis (strain CIRAD86) GN=MYCFIDRAFT_28021 PE=4 SV=1
-----------------------------------LLQKSSKILVITGAGISTSLGIPDFRSKTGFYDKIQ--QMGRDD--IAEPQDVFD----DPGEIL
PDRSGYTPTHGFIQLLDQM-GKLQTNYTQNIDNLEGIAGINKVIQCHGSFKTASCRKCKHKVDGEDDIRNVPKCKQCEKPGVMKPDITFFGELPEDFTRF
EKDAKDTDLVIVIGTSLKVAPV----SEMPNYHVPHIYISMEPIR-HVEFDIQLLGKCDEVVAALCKKA----------
>tr|A0A0A1NHG5|A0A0A1NHG5_9FUNG Uncharacterized protein OS=Rhizopus microsporus GN=RMCBS344292_06339 PE=4 SV=1
-----------------------------------LLSKANNIMIVTGAGVSVSCGIPDFRSETGIYSRLQ--E---YE--LDDPQQMF-YFRETPKELY
PTNYEPSPSHLFVKLVEDK-GKLLRNYTQNIDTLEHKAGIKRVVNCHGSFATASCVTCGYKVDGESYIMAVPPCPKCGVVSIMKPDITFFGELPSEFDNL
ALDTQHVDLLIVMGSSLKVSPV----SEIMQQSVPQILINRTPIT-HMTFDIQLLGDCDIIVPEICRRL----------
>tr|I2JY25|I2JY25_DEKBR Hst4p OS=Brettanomyces bruxellensis AWRI1499 GN=AWRI1499_2229 PE=4 SV=2
-----------------------------------AITYSKRVVMVIGAGVSVGAGIPDFRSSNGLFQGLATKSSGSGKNVFRSDGSIKKFESMIHYTL-
SNECDPTYYHHMIDKISEQ-GRLLRLYTQNIDCLDVQLPYPKCIQLHGNIQLMNCSKCRYITPLNETFFKKVRCPECQNEGILRPRIVLYNEFHPDGEII
TESKSRPDCLIVTGTTLKIPGVRRLVKEMARNKGYVIWVNIDPPTSVEYFDLLVIGS-CQXVPGLVSL-----------
>tr|W1QBY2|W1QBY2_OGAPD Hst4p OS=Ogataea parapolymorpha (strain DL-1 / ATCC 26012 / NRRL Y-7560) GN=HPODL_04178 PE=4 SV=1
-----------------------------------SLETSKKIVAITGAGISVGSGIPDFRSANGLFQGFASKTNGSGKNVFRSPESLKEFEKMIRYTL-
SVECEPSPFHRLLDKISQE-GRLLRLYTQNIDCLDTQLPYPKTIQLHGNIKLLNCSKCHHVKELDESYFNERNCPECESGGVLRPRIVLYNEFHPDGEII
TESKNRPDCLLVVGTTLKIPGVRRLVKEMAKKNGSVIWINIEEPTSVEHFDLIVTGS-CQDIPVLLDA-----------
>tr|F2QZ40|F2QZ40_PICP7 Uncharacterized protein OS=Komagataella pastoris (strain ATCC 76273 / CBS 7435 / CECT 11047 / NRRL Y-11430 / Wegner 21-1) GN=PP
-----------------------------------ALINSQRIIVVNGAGVSVASGIPDFRSSKGIFSKYG---GSSGKDLFRSSDKIQQFTSMIRSSL-
VERSKPSKFHHFINELAKT-SNLLRVYTQNIDCLELQCPFPNVIQLHGNIKQVSCTKCHINYPLGPNFSAKMSCPECIGHGILKPKIILYNEHHPDGEAI
SEMKSRPDCLIVAGTSLKIPGVKRMVKEFAKCKGCVIWLNKEPPPSIENMDLIVVAD-CDSIPDLVSG-----------
>tr|A0A099P3A2|A0A099P3A2_PICKU Uncharacterized protein OS=Pichia kudriavzevii GN=JL09_g2081 PE=4 SV=1
-----------------------------------ALTYSKKTVFITGAGISVNSGIPDFRSANGLFQGLATKTTGSGRNLFRDPDSITMFEGMIEYNL-
SRVAEPSPFHKMINDVSKQ-GRLLRLYTQNIDCLDTQLPTPKTIQLHGSISLLNCSKCNYISELSKEYFNQRSCPSCENVGILRPRIVLYNEFHPDGEVI
TEKKSKPDCLIVSGTTLKIPGVRRLVKEMSRNKGYVIWMNIDEPPNVDYFDLVIIGD-CQVIPGLVKL-----------
>tr|W6MR83|W6MR83_9ASCO Uncharacterized protein OS=Kuraishia capsulata CBS 1993 GN=KUCA_T00003741001 PE=4 SV=1
-----------------------------------ALEYSQRMVVVSGAGISVGSGIPDFRSANGLFQGLSSQPGGSGKQVFRSEESTQKFHKMIQFQM-
SREAEPSKFHRYIDKVSGS-DRLVRLYTQNIDCLEIQLPFPKTIQLHGNVQLMSCSKCKYTTNMDPSFFEHGICPECEGCGVMRPRIVLYNEFHPDGETI
SATRAKPDCLVVVGTTLKIPGVRRLVKELSRQKGCIIWINTEMPSSVEHFDLIVVGD-CQLIPTIMEK-----------
>tr|E7NN68|E7NN68_YEASO Hst1p OS=Saccharomyces cerevisiae (strain FostersO) GN=FOSTERSO_4384 PE=4 SV=1
-----------------------------------TLRNAKKILVLTGAGVSTSLGIPDFRSSEGFYSKIRHLGLEDPQDIFLQDPSVFY--NIAHMVL-
PPENMYSPLHSFIKMLQDK-GKLLRNYTQNIDNLESYAGPDKLVQCHGSFATASCVTCHWQIPGEKIFENIPLCPYCYSYGVLKPDMTFFGEALPSRFH-
RKDILECDLLICIGTSLKVAPVSEIVNMVPS----QILINRDMVT-HAEFDLNLLGF-CDDVASLVAK-----------
>tr|Q875P9|Q875P9_LACKL HST1 OS=Lachancea kluyveri PE=4 SV=1
-----------------------------------KLKTARRVLVLTGAGISTSLGIPDFRSSEGFYSKIKHLGLDDPQDIFMQDPSVFY--NIAHMVL-
PPENLYSPLHSFIRMIQDK-GKLLRNYTQNIDNLESYAGAEKMVQCHGSFATASCVTCHWKLPGEKIFGNIPLCPYCYSYGVLKPDITFFGEALPSKFH-
REDVLKCDLLICIGTSLKVAPVSEIVNMVPA----QVLINKDPVK-HAEFDLSLLGF-CDDVAALVAQ-----------
>tr|C4YJ93|C4YJ93_CANAW Putative uncharacterized protein OS=Candida albicans (strain WO-1) GN=CAWG_03906 PE=4 SV=1
------------------------------------LSKAKKIMVVTGAGISTSLGIPDFRSFKGLYNQLKVFDLQ---TFMREPGL---FYTIAHLVL-
PPDGKFSLLHAFLKLLQDK-HKLLRNYTQNIDNLEQRAGLEKLVQCHGSFAKAKCVSCQGIFAGEKIYKQVPRCAICWKFGAIKPTITFFGELPERFHTM
DKDLQQIDLFLVIGTSLKVEPVASIIERV-PYKVPKILINKDPIPNRG-FNLQLLGLCDDVVSYLC-------------
>tr|C5M5U2|C5M5U2_CANTT NAD-dependent histone deacetylase SIR2 OS=Candida tropicalis (strain ATCC MYA-3404 / T1) GN=CTRG_01223 PE=4 SV=1
------------------------------------LTMAKKIVVITGAGISTSLGIPDFRSFQGLYTQLKVFDME---TFKKDPSL---FYTIAHMVL-
PPEGKFALFHSFLKLLEDK-NKLLRNYTQNIDNLEQRAGIEKLIQCHGSFSHAKCITCGAIFKGEKIFLQVPRCSKCWEYGVIKPTITFFGELPERFHRH
SKDLKNADMVIVSGTSLNVNPVAGLVEKV-PSHVPKILINKDQIDDMGSFNLRLIGLCDEVVAWIS-------------
>tr|A3LN35|A3LN35_PICST NAD-dependent histone deacetylase SIR2 (Regulatory protein SIR2) (Silent information regulator 2) (Fragment) OS=Scheffersomyces
------------------------------------LTSAKKIMVISGAGISTSLGIPDFRSFKGLYAQLKVFDMG---AFQKDPSI---FYSIAHLVL-
PPEGRFSMLHSFIKLLQDK-GKLLRNYTQNIDNLESRVGIDKLIQCHGSFGSASCLTCSNRFAGHKIFQHVPRCSTCWKHGVIKPDITFFGELPKKFYRL
EPDCQTCDLVIVVGTSLKVEPVSSIIDKI-PRSVPRVLINKDPIPDRD-FDLSLIGLCDDVVCHLT-------------
>tr|M3K875|M3K875_CANMX NAD-dependent histone deacetylase SIR2 OS=Candida maltosa (strain Xu316) GN=G210_3413 PE=4 SV=1
------------------------------------LSLANRIMVVTGAGISTSLGIPDFRSFKGLYNQLKVFDLA---TFMEEPGL---FYSIAHMVL-
PPEGKFALLHAFLKIIQDK-GKLLRNYTQNIDNLEERAGIDKLIQCHGSFSHARCITCNSLFAGTKIYQQIPRCSQCWKHGVIKPTITFFGELPERYHNI
KSDIRNCDMCIVIGTSLNVNPVAGIIKDI-PFDVPKILINKDPIEGMGAFNLKLYGLCDEVVSYVS-------------
>tr|G3AMT6|G3AMT6_SPAPN Putative uncharacterized protein OS=Spathaspora passalidarum (strain NRRL Y-27907 / 11-Y1) GN=SPAPADRAFT_50403 PE=4 SV=1
------------------------------------LTKSSKVLVITGAGISTSLGIPDFRSFQGVYSQLKVFDKS---TFMKDPTL---FYSNAHLVL-
PPEGKYSVLHAFIKLLQDK-NKLLRNYTQNIDNLETKAGINKLIQCHGSFAEATCITCKNKFLGAKIFQQVPRCSTCWAHGVIKPDIVFFGELPKKFHRL
HSDVKSCDLVLVIGTSLKVEPVASIIDKV-PRRVPRVLINKDPIPDRD-FDLSLIGYCDDIVSYLV-------------
>tr|C4JJT3|C4JJT3_UNCRE Putative uncharacterized protein OS=Uncinocarpus reesii (strain UAMH 1704) GN=UREG_01890 PE=4 SV=1
---------------------------------------NAQTVLLTGAGISVASGLSDYRGERGTYRRNA---S-----Y--RPIYFHEFVAARKRTLR
--DAGPNSTHSCIAALGR-KGYISSVITQNVDSFHNIAHPIPVVELHGYLRSVICVNCRHTMPWAEFLWRYPPCPRCLITGILKPAVVMFGEVDETTLAA
EEAIDEAGKLLVMGTSLATFSAWRLVERAQRRGMAIGILNMGGVRNEAALFEGANEKTELVLPEVVSRLEQ--------
>tr|C5P168|C5P168_COCP7 Sir2 family transcription regulator OS=Coccidioides posadasii (strain C735) GN=CPC735_071080 PE=4 SV=1
---------------------------------------NAQTVLLTGAGISVASGLSDYRGENGTYRRNA---S-----Y--RPIYFHEFVTARKRTLR
--DSGPNSTHFCIAELGR-KGYISSVITQNVDSFHNVAHPLPVLELHGYLRSIVCVNCRHMMSWSEFLARYPPCPRCLLTGILKPAVVMFGEVDEATTAA
EEAIDEAGKLLVMGSSLATFSAWRLVERAQNRGMSIGILNVGGVRNEASLFKEGNEKTELVLPEVVSRLEQ--------
>tr|A0A0E9NEH8|A0A0E9NEH8_9ASCO Uncharacterized protein OS=Saitoella complicata NRRL Y-17804 GN=G7K_2429-t1 PE=4 SV=1
---------------------------------------PRSTLLLTGAGVSVDSGIPDYRGPTGTYRVNK---S-----Y--RPIFFSEFTESRQRPVQ
--RARPNDIHKRVAGLWR-HGHLSQVITQNVDGLHTASSPDVTLELHGSLHKVLCLSCRGHIHWAELLRMYPACKKCDAAGILKPSVIFFGEVPESHIAA
EKAVEQADRVLVIGSSLATYSAFRLIRAAKETGKSVAVVNWGGIRGEGEILIEEEG-----LAEVESMLME--------
>tr|N1QAG5|N1QAG5_PSEFD Uncharacterized protein (Fragment) OS=Pseudocercospora fijiensis (strain CIRAD86) GN=MYCFIDRAFT_14817 PE=4 SV=1
---------------------------------------GGKTLILSGAGISVASGLADYRGSQGTYTLNK---T-----Y--RPIYFHEFTAARKRTLH
--RSTPNAAHHAVGRLGN-LGYVGKVITQNVDSFHQKAHPLSSLELHGYLRSTVCLTCRTEYDWASFLAEYPPCPKCLNDGVLKPAVIMFGEISNPVVAV
ESAIDHSSSMLILGSSLATYSAWRLVKRAKEQGKAIAAVNIGGLRGEEQFFADVAAPLEQVLPALV-------------
>tr|U4LT91|U4LT91_PYROM Similar to NAD-dependent protein deacetylase SIR4 acc. no. F4P804 OS=Pyronema omphalodes (strain CBS 100304) GN=PCON_08978 PE=4
---------------------------------------HNRTLLLTGAGISVASGLSDYRGTQGTYRLNQ---S-----Y--RPIFFHEFTSSRQRSVA
--AAKPNTAHHAIKKLWD-LGLSSGVLTQNVDSLHGWG-KDMVVELHGTLRDVICLGCGDKMEWRKLKA-YPVCPHCAKRGVLKPCVTFFGEVGEDNSRA
EELVEDAKGVLVVGSSLATYSAWRLVKEAKRQGKGIAVVNIGGIRGEEEFRDGKSQ-----LKGVVERLGE--------
>tr|C5FSW1|C5FSW1_ARTOC Silencing information regulator OS=Arthroderma otae (strain ATCC MYA-4605 / CBS 113480) GN=MCYG_05783 PE=4 SV=1
---------------------------------------NEQTVLLTGAGISVASGLADYRGENGTYRRNV---A-----Y--RPIYFHEYVGARQRTMG
--RSKPNVTHESIGRLGR-KGYISSVITQNVDSLHSQAHPLPVLELHGYLRSVICVSCRHKIPWADFLNRYPVCPRCLESGILKPAVVMFGEVNGEVVAA
EEAVDEAGKLLVLGTSLATFSAWRLVERALARGMSIGVVNVGGIRNEAALFRDIDAPAEAVMPEVAARLQA--------
>tr|D4AYL2|D4AYL2_ARTBC Uncharacterized protein OS=Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) GN=ARB_01281 PE=4 SV=1
---------------------------------------NEQTVLLTGAGISVASGLSDYRGEKGTYRRKA---G-----Y--RPIFFHEYVTARQRTMG
--RSKPNITHDTIGQLGE-KGYISAVITQNVDSLHRRAHPLPVVELHGDLRSVVCVTCAHRIPWADFFYQYPACPRCLERGILKPAVVMFGQVDDEVRAA
EEAVDEAGKLLVLGSSLATFSAWRLVERAVNRGMAVGVLNVGGFRNEALLFGSVQPPAEDILPHVAARLAA--------
>tr|A0A0N1HH45|A0A0N1HH45_9EURO NAD-dependent protein deacetylase SIR4 OS=Phialophora attae GN=AB675_2425 PE=4 SV=1
---------------------------------------VPKTVLLTGAGISVASGLADYRGKDGTYTSNP---K-----Y--RPVYYHEFLAWRKRSLL
--SSKPNSSHRAVASLDS-LGILSSCITQNVDSFHPRSHPLPTIELHGYLRSLLCLSCGTLHPWKSFLASYPPCPKCLKSGILKPNVIMFGEIPAQIAAA
EDAINSADRMLIIGSSLATYSAWRLVKQAFDQSMPIGVLNIGGVRKEEGFFPPESRSSESVLPEVVEMLRR--------
>tr|W2S6X5|W2S6X5_9EURO Uncharacterized protein OS=Cyphellophora europaea CBS 101466 GN=HMPREF1541_10598 PE=4 SV=1
---------------------------------------PPKTALLTGAGISVASGLADYRGKDGTYTSNP---S-----Y--RPVYYHEFLSWRKRSLL
--SSKPNLSHRAVASLHS-LGLLSSCITQNVDSFHPKAHPLPTIELHGYLRALLCLSCGTLHPWKTFLASYPPCPKCLKTGILKPNVIMFGEIPSNVMAA
EDAINSADRLLVIGSSLATYSAFRLAKQAFDRGIPIGILNLGGVRKEEAFFTPESRACEDVLPKVVERFKA--------
>tr|S8BGE4|S8BGE4_PENO1 Uncharacterized protein OS=Penicillium oxalicum (strain 114-2 / CGMCC 5302) GN=PDE_09156 PE=4 SV=1
---------------------------------------NRQTVLLTGAGISVASGLSDYRGDQGTYRRNK---A-----Y--RPIYFHEFTAARQRGLV
--SAKPNSTHHAVRDLGT-KGYISSVVTQNVDSFHSIAHPLPSIELHGYLRSVVCVSCRNQLPWAEFLARYPSCPTCLERGILKPAVIMFGEIDPAVAAA
EEAIDDAGRLLVLGSSLATYSAWRLVERAYKRGMPIGIINVGGVRNEAMLFGELGSPTQDILPTVVAGLPR--------
>tr|A0A0D9LGP3|A0A0D9LGP3_9EURO Sirtuin family OS=Penicillium solitum GN=U727_00433780321 PE=4 SV=1
---------------------------------------HSQTVLLTGAGISVASGLSDYRGDQGTYRRNK---S-----Y--RPIYYHEFISSRKRGLL
--KAKPNSTHWAIKGLGE-KGYISSVVTQNVDSFHSLAHPLSTLELHGYLRSVVCTSCRSQLPWAEFLARYPSCPTCLENGILKPAVIMFGEIDPLVTAA
EEAIDDAGRLLILGTSLATFSAWRLVERAHKRGMPIGIVNVGGVRNEAVLFENIGHPSQSVLPTVVSQLPV--------
>tr|B6QNA9|B6QNA9_TALMQ SIR2 family histone deacetylase, putative OS=Talaromyces marneffei (strain ATCC 18224 / CBS 334.59 / QM 7333) GN=PMAA_052070 PE
---------------------------------------NAQTVILTGAGISVASGLSDYRGENGTYVRNK---S-----Y--RPTYYHEFITARKRGLL
--KAKPNTTHKAVTDLGK-KGYVSNVITQNVDSFHMVAHPLSTIELHGFLRGVICINCHNLVPWAEFLHEYPACPHCLEKGILKPAVIMFGETSPSVSAA
EEAIDDAGRLLIMGSSLATYSAYRLVERAHKRGMAIGIINVGGVRNESQIFGNLLSKSETVLPEVASRLPV--------
>tr|A0A0D2A1E6|A0A0D2A1E6_9PEZI Uncharacterized protein OS=Verruconis gallopava GN=PV09_08322 PE=4 SV=1
---------------------------------------ASNTVLLSGAGISVASGLADYRGTNGTYTLNK---S-----Y--RPIYYNEFTSARRRNLV
--RAKPNATHYAVRDLGK-LGIVKQVITQNVDSFHPAAHPLPTIELHGYLRATVCLSCRKEYDWHEFLQEYPACPTCLNSGILKPAVVMFGEIPAAVTAT
ESAIDRASRLLVVGSSLATYSAWRLVKRAKEQGLAIAILNLGGVRGEEHFFADVPAHSDHVLPHVVKILEE--------
>tr|A0A0L6UTX8|A0A0L6UTX8_9BASI Uncharacterized protein OS=Puccinia sorghi GN=VP01_3737g1 PE=4 SV=1
---------------------------------------AGNLLAISGAGISCSYRFPSARGACQSYIINK---S-----Y--RPIFFQLSVGFRIRTVR
--AAEPNVGHYALAALMK-MGYIRHLITQNVDRLHHKAIGHPILELHGTLKHVNCLSCGHQMDWKDYADTVPNCEKCRV-GLLKPAVTFFGELSKEAEES
NVRVREAKGLLLLGTSLTTYSAFRLVKELKEDTQQIGMINIGATRADALV--------SQVLKEAALHLAA--------
>tr|R7YMV7|R7YMV7_CONA1 Uncharacterized protein OS=Coniosporium apollinis (strain CBS 100218) GN=W97_02464 PE=4 SV=1
---------------------------------------NDKTVLLTGAGISVASGLADYRGKNGTYTLNK---T-----Y--RPIYFNEFCSARKRNLH
--KARPNTAHYAVGRLGE-LGKVGGVITQNVDSFHPTAHPLPTLELHGYLRSLVCLTCRNEYSWAAFLQEYPACPTCLANGILKPAVIMFGEIPGPVEAA
EEAVDTSSRILVIGSSLATYSAWRLVKKAKENGMPIGILNIGGVRGEETFFADVPPSADQVLPEVVKMLER--------
>tr|N1QI34|N1QI34_SPHMS DHS-like NAD/FAD-binding domain-containing protein OS=Sphaerulina musiva (strain SO2202) GN=SEPMUDRAFT_146044 PE=4 SV=1
---------------------------------------GDKTVILSGAGISVASGLADYRGSQGTYTLNK--------------IYFHEFAAARKRTLH
--RSQPNQAHYAVGALAD-LGYISKVITQNVDSFHPKAHPLPTLELHGYLRSCVCLTCRSEYPWAQFLQEYPPCPKCLADGILKPAVIMFGEIPNAVVAA
EEAVDEASSVLVLGSSLATYSAWRLIKRAKEHGKRIAAINMGGIRGEEAFFQHLPAPLEQALPALVETLQE--------
>tr|N1Q4D1|N1Q4D1_DOTSN Sir2 class like protein OS=Dothistroma septosporum (strain NZE10 / CBS 128990) GN=sir2 PE=4 SV=1
---------------------------------------NGKTLVLSGAGMSVASGLADYRGTNGTYTLNK---T-----Y--RPIYFHEFSAARKRTLH
--RSNPNPAHYAVGKLGE-LGHVSQVITQNVDSFHPKAHSLKTLELHGYLRSTVCLTCRSEYSWSAFLAEYPPCPRCLADGILKPAVIMFGEIPGQVVDV
EAAVDESSRLLVLGSSLATYSAWRLVKRAKQQGKIIAAINQGGVRGEDNFFADLSMPLEETLPALVKALQM--------
>tr|F9WZ89|F9WZ89_ZYMTI Uncharacterized protein OS=Zymoseptoria tritici (strain CBS 115943 / IPO323) GN=MYCGRDRAFT_34913 PE=4 SV=1
---------------------------------------NNKTLILSGAGISVASGLADYRGTNGTYVLNK---T-----Y--RPIYFHEFSAARKRTLH
--RSRPNPAHHAVKRLGE-LGLVSTVVTQNVDSFHGEAHPLRTLELHGYLRATVCLTCRSEYSWAKFLAEYPPCPKCLAEGILKPAVIMFGEIPNSVVEV
ENAVDEASQLLVLGSSLATYSAWRLVKRAKEQGKPIAAVNMGGVRGEENFFADVPAPLEQTLPALVEELMR--------
>tr|S8A6Q8|S8A6Q8_DACHA Uncharacterized protein OS=Dactylellina haptotyla (strain CBS 200.50) GN=H072_7502 PE=4 SV=1
---------------------------------------SRSTLVLSGAGISVASGLPDYRGPQGTYTLNK---E-----Y--RPIFYGDFVHMRRRGVE
--KVRPNRTHVSVGRLWE-GGWVGGVITQNVDSLHSISHPDMITNLHGLLSTLLCLTCRKKFAWSEYLEKYPPCQECFKNGVMKPTLVFFGELREEVKEA
EQRVDNADSILVLGSSLATYSAWRLVKRAKDQGKKVGIVNLGGVRGEDGFWDDGEG-----LEGVLDVLER--------
>tr|G1XGR0|G1XGR0_ARTOA Uncharacterized protein OS=Arthrobotrys oligospora (strain ATCC 24927 / CBS 115.81 / DSM 1491) GN=AOL_s00083g191 PE=4 SV=1
---------------------------------------TRSTLVLSGAGISVASGLPDYRGPQGTYTLNK---E-----Y--RPIFYGDFVHMRRRGVE
--RVRPNKAHVTVGRLWE-GGWIGGAITQNVDSLHTMSHPDMITNLHGLLSTVLCLTCRTHSEWSEFLEKYPPCQTCLKNGIVKPTLVFFGELRDEIKEA
EGKVDAADSVLVIGSSLATYSAWRLVKRAKDQGKKVAIVNLGGVRGEDAFWDDGEG-----LEGALNILER--------
>tr|C1GKB7|C1GKB7_PARBD Uncharacterized protein OS=Paracoccidioides brasiliensis (strain Pb18) GN=PADG_07703 PE=4 SV=1
---------------------------------------RTQTTLLTGAGISVPSGLSDYRGPNGTYRLNT---A-----Y--KPIYHHEFLTSRKRTLS
--RARPNKTHIAIGELAK-KGYVGAVVTQNVDSLHDGVMDVPVVELHGCLREVVCVSCSGRMGWAERLEEYPPCPHCLESGILKPAVIMFGEVDGAVQRA
EEAVDGAGKLLVLGSSLATFSAWRLVERAVRKGMAVGILNVGGVRGEERLFGEFGERVEDVLPEVAALLEG--------
>tr|D5GQ03|D5GQ03_TUBMM Uncharacterized protein OS=Tuber melanosporum (strain Mel28) GN=GSTUM_00012119001 PE=4 SV=1
----------------------------------------RDVVILTGAGISVESGLADYRGEKGTYRLNR---T-----Y--RPIFYEEFAGARKRTME
--KAQPNRVHRSISILGK-LGVLNHVITQNVDSLHHTCHPHLTTELHGTLQTLICLTCRSPYPWAEFLHIYPPCPKCLNSGVLKPSVTFFGEILLEATKA
EEMVDKCGGILVVGTSLATYSAYRLVKASHDAGKGVGIVSLGGVRGEGLFFSEGSK-----LGGVVKNFGG--------
>tr|A0A010Q9R2|A0A010Q9R2_9PEZI Sir2 family protein OS=Colletotrichum fioriniae PJ7 GN=CFIO01_11439 PE=4 SV=1
---------------------------------------R-STVVLTGAGLSVSSGLADYRGVNGTYRVNK---T-----Y--RPIYYHEFLAARKRSLH
--KASPNHGHYAIRDMGQ-MG-IRSVITQNVDSFHSTAHPIPTLELHGYLRSTVCVTCRNEYPWAAFLVEYPACPHCLAKGILKPAVVMFGEIPNDVTAA
EEAINGAGKLLILGTSLATYSAWRLAKMALDRGMPIAVVNTGGVRGEDQISAVEDPSTDVVLPALVEQLHK--------
>tr|A0A084APF8|A0A084APF8_STACH Uncharacterized protein OS=Stachybotrys chartarum IBT 7711 GN=S7711_03047 PE=4 SV=1
---------------------------------------N-TTVVLTGAGISVASGLADYRGVKGTYRVNK---T-----Y--RPIYYHEFIGARKRSLH
--GASPNSGHYAIRDLGD-LG-VHSVITQNVDSFHPKAHPIPSLELHGYLRATVCVSCKTEYPWAELLQAYPPCPRCLTSGVLKPAVVMFGEIASSVTAA
EEAIDSAGKLLVMGTSLATYSAWRLAKRAKDRGMPMALVNIGGVRGEDQLFTSTPPPTDELLPALVAQLRS--------
>tr|E3RXQ2|E3RXQ2_PYRTT Putative uncharacterized protein OS=Pyrenophora teres f. teres (strain 0-1) GN=PTT_14208 PE=4 SV=1
---------------------------------------TGKTLLLTGAGISVASGLADYRGTKGTYTLNK---G-----Y--KPVYFHEFCDARKRTLE
--RAGPNRAHVACGELGK-LGVVGGVVTQNVDSFHPIAHPLPTTELHGYLRNLVCLTCRSEYPWSAFLAEYPACPTCLKKGVLKPAVIMFGEIPVKTVAA
ETAVDEAGRVLVIGSSLATYSAWRLVKKAKEMGLPIGVLNIGGVRGEETFFGDVGESAETVLPEVVGILEG--------
>tr|M2UQ03|M2UQ03_COCH5 Uncharacterized protein OS=Cochliobolus heterostrophus (strain C5 / ATCC 48332 / race O) GN=COCHEDRAFT_1178137 PE=4 SV=1
-----------------------------------------KTLLLTGAGISVASGLADYRGANGTYTLNK---T-----Y--RPIYYNEFCDARKRHLE
--RARANAAHVACGELGR-LGVVGRVITQNVDSFHPTTHPLATIELHGYLRNLVCLSCRNEYSWAAFLAEYPACPTCLEKGVLKPAVIMFGEIPAATVAA
EQAVEAAARVLVIGSSLATYSAWRLVKKAKEMRLPIGVLNMGGVRSEETFFGDMNNNAERILPSVVEILAQ--------
>tr|W6ZVE9|W6ZVE9_COCMI Uncharacterized protein OS=Bipolaris oryzae ATCC 44560 GN=COCMIDRAFT_34799 PE=4 SV=1
---------------------------------------AKKTLLLTGAGISVASGLADYRGANGTYTLNK---T-----Y--RPVYYHEFCEMRKRNLE
--RARANAAHVACGELGS-LGVVGGLVTQNVDSFHPTTHPLPTIELHGYLRNLVCLTCRNEYSWAEFLAEYPACPTCLEKGVLKPAVIMFGEIPAATVAA
EQAVEAAGRILVIGSSLATYSAWRLVKKAKEMHLPIGVLNMGGVRGEETFFGDIKDNAERILPSVVGVLQQ--------
>tr|G2QDA5|G2QDA5_MYCTT Uncharacterized protein OS=Myceliophthora thermophila (strain ATCC 42464 / BCRC 31852 / DSM 1799) GN=MYCTH_81379 PE=4 SV=1
---------------------------------------PRSTVVLTGAGLSVASGLADYRGPNGTYRVNK---T-----Y--RPIYYHEFLTARKRTLR
--NAQPNPGHYAVRDLGR-LG-VSAVVTQNVDSFHPRAHPIPTLELHGYLRSTVCTSCRTEMPWDAFLQEYPACPKCLSDGILKPAVVMFGEIADGVKAA
EEAIDGAGKLLVLATSMATYSAWRLAKRAKDRGMPVAIVNIGGVRGEEAFFAGLDPSTETLLPALVRELRQ--------
>tr|Q2H6R0|Q2H6R0_CHAGB Putative uncharacterized protein OS=Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970) GN=C
---------------------------------------PRSTVLLTGAGLSVASGLADYRGTNGTYRVNK---T-----Y--RPIYYHEFLSARKRTLR
--NAAPNAGHYAVRDLGK-LG-LSSVITQNVDSFHPRAHPIPTLELHGYLRSAVCTSCRNELPWDAFLREYPACPTCLSSGILKPAVVMFGEIASSVEAA
EDAIDGAGKLLVLATSMATYSAWRLAKRAKDRGMPIGIVNIGGVRGEDLFFGGLDPSTDSLLPALVHDMRQ--------
>tr|G0SHM1|G0SHM1_CHATD Putative NAD binding protein OS=Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719) GN=CTHT_0070520 PE=4 SV=1
---------------------------------------PLSTVVLTGAGLSVASGLADYRGAKGTYRVNR---T-----Y--RPIYYHEFLTARKRTLR
--DAEPNAGHYAIGELGK-LG-VRSVVTQNVDSFHRRAHPLPTLELHGKLRATVCVSCGGEFEWEGFLREYPACPKCLMDGVLKPAVVMFGEIAPEVQAA
EEAIDNAGKLLVLATSLATYSAWRLAKRAKDRGMPIAIVNIGGVRGEEVFFADVSPSTEELLPALVQELRG--------
>tr|A0A0M0U773|A0A0M0U773_9PEZI NAD-dependent protein deacetylase SIR4 OS=Madurella mycetomatis GN=MMYC01_G06450 PE=4 SV=1
---------------------------------------PPSTVVLTGAGLSVASGLADYRGTHGTYRVNK---T-----Y--RPIYYHEFLSARKRTLN
--KASPNVAHYAIRDLGR-LG-VSGVVTQNVDSFHARAHPIPTLELHGYLRSTVCTSCWNEFPWNTFLQEYPACPKCLNSGILKPAVVMFGEIPDRVRAA
EDAIDGAGRLLVLATSLATYSAWRLVKRAKDRGMPIAIVNMGGVRGEEIFFADLDGSTESLLPALLSELRQ--------
>tr|G2R9B2|G2R9B2_THITE SIR2 family histone deacetylase-like protein OS=Thielavia terrestris (strain ATCC 38088 / NRRL 8126) GN=THITE_43883 PE=4 SV=1
---------------------------------------PRSTVVLTGAGLSVASGLADYRGANGTYRVNK---T-----Y--RPIYYHEFLAARKRTLR
--SAAPNAGHYAVRDLGR-LG-VSRVITQNVDSFHPRAHPIPTLELHGYLRSTVCTSCWNEFPWDAFLREYPACPKCLSSGILKPAVVMFGEIANGVQAA
EDAIDGAGRLLVLATSLATYSAWRLAKRAKDRGMPIAIVNIGGVRGEDAFFADLDPSTDSLLPAVVHELRQ--------
>tr|N4VJC8|N4VJC8_COLOR Sir2 family transcriptional OS=Colletotrichum orbiculare (strain 104-T / ATCC 96160 / CBS 514.97 / LARS 414 / MAFF 240422) GN=C
---------------------------------------P-STVVLTGAGLSVSSGLADYRGVNGTYRVNK---T-----Y--RPIYYHEFLAARKRSLH
--KASPNNGHHAIRDLGQ-LG-IRSVITQNVDSFHSKAHPIPTLELHGYLRSTVCVTCRNEYPWAAFLVEYPACPQCLTHGILKPAVVMFGEIANEVTSA
EEAIDGAGRLLVLGTSLATYSAWRLAKRALDRGMPIAIVNTGGVRGEEKLAAVPDPSTDAVLPALVEQLQQ--------
>tr|B2AXF9|B2AXF9_PODAN Podospora anserina S mat+ genomic DNA chromosome 7, supercontig 1 OS=Podospora anserina (strain S / ATCC MYA-4624 / DSM 980 / F
---------------------------------------PPSTVVLTGAGLSVASGLADYRGVKGTYRVNK---T-----H--RPIYHHEFISTRKRTMS
--MANPNSGHYAIRDLGK-LG-VKGVITQNVDSFHPRAHPMPTVELHGYLRSAVCITCRNEYPWKDFLKEYPACPTCLTRGILKPAVVMFGDISPEVHDA
NKTIDNAGRLLVMGTSLATYSAWRLAKRAKDRGMPIAVINMGGVRGEEAFFTDLDPSTESLLPALVQAMRK--------
>tr|A0A0P4UES7|A0A0P4UES7_ROSNE Putative sir2 family protein OS=Rosellinia necatrix GN=SAMD00023353_4100790 PE=4 SV=1
---------------------------------------RQSTAVLTGAGISVASGLPDYRGTKGTYRVNK---T-----Y--RPIYYQEFLHARKRTLQ
--NGRPNATHFAIKHLND-LG-VRSVITQNVDSFHPQAHPLPTVELHGYLRSCICASCHQELPWAAFLEEYPACPTCLAEGFLKPAVVMFGEIRHSVAAA
EQMINDADRLLVLGTSLATYSAWRLAKQAKDQGKPIAIVNLGGVRGEDAFFGHLDPSTDEILPSLVEQLRR--------
>tr|A0A0L1JAD1|A0A0L1JAD1_ASPNO Putative SIR2 family histone deacetylase OS=Aspergillus nomius NRRL 13137 GN=ANOM_002725 PE=4 SV=1
---------------------------------------HSQTVLLTGAGISVASGLSDYRGENGTYVTNK---T-----Y--RPIYFHEFLTFRKRGLV
--KAKPNSTHWAIRDLSA-KGYLSSVVTQNVDSFHPIAHPLPTIELHGYLRSVVCTSCHNQFPWAEFLAKYPACSTCLEKGVLKPAVTMFGEIHPAVTAA
EEAIDDAGRLLILGSSLATFSAWRLVERAHKRGMPIGIINIGGVRNESVLFGKMEPNSDLILPPVAAQLPS--------
>tr|A0A0J5PR51|A0A0J5PR51_ASPFM SIR2 family histone deacetylase OS=Aspergillus fumigatus Z5 GN=Y699_00367 PE=4 SV=1
---------------------------------------HSQAVLLTGAGISVASGLSDYRGEKGTYVTNK---F-----Y--RPIYFHEFLSSRKRGLL
--KAEPNSTHWAIRDLAA-KGFVSSVVTQNVDSFHSIAHPLPTIELHGHLKSVVCTSCRNQFSWAEFLARYPSCPTCLENGILKPAVVMFGEIDPGVTAA
EEAIDDAGRLLILGSSLATYSAWRLVERAHRRGMPIAIINLGGVRNESVLFETSSDPSEAILPPVVSLLPK--------
>tr|A1C4S7|A1C4S7_ASPCL Sir2 family transcriptional regulator, putative OS=Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / 
---------------------------------------HSQTVLLTGAGISVASGLSDYRGENGTYVTNK---T-----Y--RPIYFHEFLTSRKRGLA
--KAKPNTTHWAVRDLSA-KGFVSTVVTQNVDSFHSVAHPLPTIELHGYLRSVVCTSCRNEFSWAEFLARYPSCPTCLESGILKPAVIMFGEIDREVMAA
EEAIDDAGRLLILGSSLATYSAWRLVERAHKRGMPIAIINLGGVRNESVLFGAGTDSSEAILPPVVAQLPR--------
>tr|Q0CE82|Q0CE82_ASPTN Putative uncharacterized protein OS=Aspergillus terreus (strain NIH 2624 / FGSC A1156) GN=ATEG_08002 PE=4 SV=1
---------------------------------------NAQTVVLTGAGISVASGLSDYRGENGTYVTNK---T-----Y--RPIYFHEFVKFRKRGLV
--KAKPNLTHWAIRDLGA-KGYISSVVTQNVDSFHSIAHPLTTLELHGYLRSVVCLSCRNQFPWAEFLARYPSCPTCLEKGVLKPAVVMFGEIDPRVVAA
EEAIDDAGRLLVIGSSLATYSAWRLVERAHKRGMPIGIINIGGVRNESALFGSAHDHSESVLPPVVSQLPE--------
>tr|A0A0F8U881|A0A0F8U881_9EURO Putative SIR2 family histone deacetylase OS=Aspergillus rambellii GN=ARAM_002805 PE=4 SV=1
---------------------------------------YSQTAILTGAGISVASGLSDYRGENGTYVTNK---A-----Y--RPIYFHEFAAARKRGLL
--KAKPNSTHWAIKDLGA-KGYISSVVTQNVDSFHSVAHPLSTLELHGYLRSVVCLSCRNQFPWAEFLEKYPSCPTCLEKGILKPAVIMFGEIDPAVVAA
EEAIDDAGRLLILGTSLATFSAWRLVERAYKRGMPIGIINLGGIRNESVLVKEADQHSDAILPSLIEQLPN--------
>tr|G7XMZ1|G7XMZ1_ASPKW Silencing information regulator OS=Aspergillus kawachii (strain NBRC 4308) GN=AKAW_06291 PE=4 SV=1
---------------------------------------HSQTVLLTGAGISVASGLSDYRGENGTYITNK---T-----Y--RPIYYHEFVAFRKRGLL
--KAKPNSTHWAIKDIGT-KGYISSVVTQNVDSFHSVAHPLPTLELHGYLRSAVCINCRTEVPWAEFLKKYPACPTCLEKGILKPAVIMFGEIDPAVVGA
EEAIDDAGRLLVLGSSLATYSAWRLVERAYKRGMPIGIINIGGVRNESILFSKAEQPSQDILGPVAAQLPS--------
>tr|A0A0F7TZS3|A0A0F7TZS3_9EURO Putative Sirtuin 4 OS=Penicillium brasilianum GN=PMG11_10628 PE=4 SV=1
---------------------------------------NTQTVLLTGAGISVASGLSDYRGDQGTYRRNK---S-----Y--RPIYFHEFATSRKRGLV
--KAKPNSTHWAIRDLGV-KGYISSVVTQNVDSFHSLAHPLSTLELHGYLRSVVCTSCRNQFSWAEYLARYPSCPTCLERGILKPAVTMFGEIDPAVTAA
EEAVDDAGRLLVLGSSLATYSAWRLVERAHKRGMPIGIINIGGVRNEAMLFGQLGSPAQAILPTVVSGLPR--------
>tr|A0A017SGS0|A0A017SGS0_9EURO DHS-like NAD/FAD-binding domain-containing protein OS=Aspergillus ruber CBS 135680 GN=EURHEDRAFT_411579 PE=4 SV=1
---------------------------------------NSQTVLLTGAGISVASGLSDYRGENGTYITNK---T-----Y--RPIYYHEFVTSRKRGLQ
--KAKPNTTHWAIKDLGA-KGYLSSVVTQNVDSFHSFAHPLPTIELHGYLRSVVCTTCQNQFSWAEFLAKYPSCPTCLEKGILKPAVIMFGEIDPTVTVA
EEAIDDAGRLLVLGSSLATFSAWRLVERAYKRGMPIGIINVGGVRNESLIFGAPQHLSENVLPPIAIQLPP--------
>tr|C8V3N2|C8V3N2_EMENI Silencing information regulator [Source:UniProtKB/TrEMBLAcc:Q71SB1] OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 1
---------------------------------------NSQTVLLTGAGISVASGLSDYRGENGTYVTNK---R-----Y--RPIYFHEFATSRKRGLL
--KAKPNSTHWAIRDLGV-KGYVSSVITQNVDSFHSIAHPIPSIELHGYLRSVVCLSCRNQFPWAEFLARYPSCSTCLEKGILKPAVIMFGEIEPPVLAA
EEAIDDAGRLLVLGTSLATYSAWRLVERAYKRGMPIGIINIGGVRNESVLLKEADKHSDAILPSVASQLPS--------
>tr|K1Y221|K1Y221_MARBU Sir2 family protein OS=Marssonina brunnea f. sp. multigermtubi (strain MB_m1) GN=MBM_02391 PE=4 SV=1
---------------------------------------PNSTVILTGAGISVASGLADYRGTNGTYRVNK---T-----Y--RPIYYHEFLAARKRNLH
--KARPNLAHYAIKSLGE-LG-VRSVVTQNVDSFHSAAHPLPTLELHGYLRALTCVTCHKDLPWAAFLVKYPACPHCLMNGILKPAVVMFGEIATTVDAA
EKAIDGSGRLLILGTSLATYSAWRLAKRANERGMPIAILNIGGVRGEEAFFQNLPMGTDRVLPGLVDQLKR--------
>tr|A0A0B1PF05|A0A0B1PF05_UNCNE Putative sir2 family protein OS=Uncinula necator GN=EV44_g6369 PE=4 SV=1
---------------------------------------PTSTVLLTGAGLSVASGLADYRGANGTYKVNK---N-----Y--RPIYYHEFISARKRNLY
--KARPNVAHFAIKELGK-MEIVRSVITQNVDSFHLMAHPLPTLELHGSLREVRCISCNKRYSWKDFFDEYPACQNCLSNGILKPDVIMFGEITSNNEAA
EQAIDNSGRLLVLGTTLATYSAWRLAKRAKDRGMPISIINLGGVRNEEYFYQDVLDKTDEVLPELVGILKT--------
>tr|W3X5M0|W3X5M0_9PEZI Uncharacterized protein OS=Pestalotiopsis fici W106-1 GN=PFICI_08010 PE=4 SV=1
---------------------------------------A-STLVLTGAGVSVASGLADYRGTNGTYRVNK---T-----Y--RPIYYSEFIQARKRTLH
--KAKPNAGHYAVKQLGD-LG-VQQVITQNVDSFHSIAHPISTIELHGYLRALVCVSCRHELPWAAFLQEYPACPRCLAHGILKPAVVMFGEIPTQITEA
DHAVESADKLLVLGTSLATYSAWRLAKRAKDRGIPVGIVNLGGVRGEEALCADLDPSTDLLLPEVVKELKQ--------
>tr|G2YRB5|G2YRB5_BOTF4 Similar to sir2 family transcriptional regulator OS=Botryotinia fuckeliana (strain T4) GN=BofuT4_P128630.1 PE=4 SV=1
---------------------------------------PQSTVILSGAGISVASGLADYRGSKGTYVLNK---S-----Y--RPVYYHEFIAARRRNLH
--KAKPNPAHYAIKDLAD-MN-VKRVVTQNVDSFHSEAHPLATVELHGYLRALTCVTCRKDLPWAAFLAEYPPCPHCLENGILKPAVVMFGEINAQVEAA
EQAIDDSGRLLVLGTSLATYSAWRLARRAQERNMPIAILNLGGVRGEEAFFKDLSGGTDIVLPALVDQLNR--------
>tr|A0A0C3HV72|A0A0C3HV72_9PEZI Uncharacterized protein OS=Oidiodendron maius Zn GN=OIDMADRAFT_154915 PE=4 SV=1
---------------------------------------PASTVILSGAGISVASGLADYRGANGTYRLNK---K-----Y--RPIYYHEFLAARKRNLH
--KARPNTTHFAVKDLGD-MG-VRSVITQNVDSFHSAAHPIPTLELHGYLRAVRCVTCHNEQPWAAFLAEYPACPHCLANGILKPSVVMFGEIDGRVEAS
EHAIDGSGKLLVLGTSLATYSAWRLARRALERGMPIAILNLGGVRGEEEFFQNLPIGTDKVLPGLVNRLKE--------
>tr|M2N6W4|M2N6W4_BAUCO Uncharacterized protein OS=Baudoinia compniacensis (strain UAMH 10762) GN=BAUCODRAFT_36090 PE=4 SV=1
---------------------------------------AGRTVILSGAGISVASGLADYRGSNGTYTLNK---T-----Y--RPIYYHEFCAARKRNLH
--RSRPNKAHEAVGRLGE-LGLLSSVITQNVDSFHPIAHSLRTLELHGYLRSTVCLSCRTEYNWAVFLAEYPACPVCLANGILKPAVIMFGEIPNSVLAV
ESAVDEAARILVLGSSLATYSAWRLVKRAQEQKKPIGVVNLGGVRGEEQFFANIATPLEEMLPMLVERLSQ--------
>tr|A0A074W5D2|A0A074W5D2_9PEZI DHS-like NAD/FAD-binding domain-containing protein OS=Aureobasidium melanogenum CBS 110374 GN=M437DRAFT_79493 PE=4 SV=1
---------------------------------------KDRTVLLTGAGISVASGLADYRGTKGTYTLNK---T-----Y--RPIYFHEFVAARKRNLN
--KSKPNPAHKAVAELGR-MGYLSSVITQNVDSFHPQAHPLRTLELHGYLRSAVCTTCRTEYDWSSFLDEYPACPSCLAKGILKPNVIMFGEIPDATVAA
EKAIDEAARVLVLGSSLATYSAWRLVKRAREQSMPIGIVNIGGVRGEEQFFAHLSPVLEEMLPNLAKELGQ--------
>tr|T5C770|T5C770_AJEDE Uncharacterized protein OS=Blastomyces dermatitidis ATCC 26199 GN=BDFG_01508 PE=4 SV=1
---------------------------------------NELTVLLTGAGISVASGLADYRGENGTYRRNL---T-----Y--RPIFYHEFISARKRTLV
--NSSPNDTHLAIAELGR-KGYISSVITQNVDSFHSKAHPIPVVELHGYLRSLVCVNCRRSMSWSEFLDQYPPCPHCLENGILKPAVIMFGEVDERVERA
EEAVDEAGKLLVLGSSLATFSAWRLVERAIARGMSIGILNVGGVRNEARVFQAANGQAEFVLPLVAAQLNA--------
>tr|J3P7L3|J3P7L3_GAGT3 Uncharacterized protein OS=Gaeumannomyces graminis var. tritici (strain R3-111a-1) GN=GGTG_09505 PE=4 SV=1
---------------------------------------PASTVCLSGAGLSVASGLADYRGDKGTYRLNK---T-----Y--RPIYYHEFLAARRRTLQ
--KAKPNVAHRAIRDLAD-LG-ISSIVTQNVDSLHWAPDQPNIVELHGYLRTLVCTSCRTEYPWAAFLAEYPACPKCLANGILKPAVIMFGEISPSVLAA
EEAVAGAGKLLVIGTSLATYSAWRLAKMAKDRGMPLAIVNIGGVRGEDAFFIDIDASTEVILPAVVEALGR--------
>tr|L7JQY7|L7JQY7_MAGOP NAD-dependent deacetylase sirtuin-4 OS=Magnaporthe oryzae (strain P131) GN=OOW_P131scaffold00027g9 PE=4 SV=1
---------------------------------------PSTTTCLTGAGVSVASGLADYRGDKGTYRVNK---S-----Y--RPIYHHEFLAARRRSLQ
--KARPNAAHRAIANLAK-MG-VSSVVTQNVDGLHHAACEPNIVELHGYLRALVCTTCKNEYPWAVFLEQYPACPSCLAHGILKPAVVMFGEIAGSVAAA
EEAVTGAGKLLVLGTSLATYSAWRLAKLAKDKGKPIAIVNMGGVRGEDAFFVEIDHPTEVILPALVEALGR--------
>tr|A0A0N0RTC6|A0A0N0RTC6_9HYPO NAD-dependent protein deacetylase SIR4 OS=Escovopsis weberi GN=ESCO_001281 PE=4 SV=1
---------------------------------------APATAILSGAGLSVASGLADYRGPKGTYRLNK---A-----Y--RPIYHHEFLHSRKRSLH
--RAAPNAAHHAIRDLAR-LG-VASVVTQNVDSFHLRAHPIPSVELHGYLRSTVCTSCHAEFPWAAVLDDYPPCPRCLADGILKPAVVLFGAISPPVQAA
EDAIDLAGKLLVLGTSLATYSAWRLARRAKDRGIPIAVVNMGGVRGEEAFFDDVDPPTDQLLPALASHLHA--------
>tr|M1W1P7|M1W1P7_CLAP2 Related to sirtuin type 4 OS=Claviceps purpurea (strain 20.1) GN=CPUR_04992 PE=4 SV=1
---------------------------------------D-STVVLTGAGLSVASGLADYRGVKGTYRVNK---T-----Y--RPIYHYEFVSVRKRSLD
--KAHPNAGHYAIRDLGN-LG-IRSVITQNVDSFHPKAHPIPCLELHGYLRATVCTSCKTEFSWAALLAEYPPCPKCLADGVLKPAVVMFGEIESQVTTA
EDSIDRSGRLLILGTSLATYSAWRLAKRARDRGMPIAIVNVGGVRGEETFFADVDPSTDEVLPALVSRLRE--------
>tr|A0A0L9SZ19|A0A0L9SZ19_9HYPO Uncharacterized protein OS=Ophiocordyceps unilateralis GN=XA68_4800 PE=4 SV=1
---------------------------------------S-EAVVLSGAGLSVASGLADYRGVNGTYRLNK---S-----Y--RPIYYAEFLDSRKRGLQ
--AASPNAGHYAIGQLGE-LG-IRSVVTQNVDSLHQRAHPLPSLELHGYLRATVCTSCQAEFSWADLLRRYPPCPRCLADGILKPAVVMFGEIIEPVRAA
EDAIDGAGKLLVLGTSLATYSAWRLARRAKERRMPVAIVNMGGVRGESQFFDQLDPAIDQILPALVSVLQK--------
>tr|A0A0A1TP87|A0A0A1TP87_9HYPO Putative Sir2 family transcriptional OS=Torrubiella hemipterigena GN=VHEMI08812 PE=4 SV=1
---------------------------------------P-STVVLTGAGLSVASGLADYRGAKGTYRVNK---S-----Y--RPIYYHEFIHARKRTLD
--RAAPNPGHYAIRDLAR-LG-VRSVITQNVDSFHQQAHSVPIIELHGYLRSTVCVSCHSEFPWDELLQEYPPCPKCLENGILKPAVVMFGEIRDSVHAA
EDAIDAAGKLLVLGTSLATYSAWRLAKRAKDRGMPIAIVNIGGVRGEELLFKDLDPSIDPLLPTLVTELGH--------
>tr|A0A0F7ZQD2|A0A0F7ZQD2_9HYPO Uncharacterized protein OS=Hirsutella minnesotensis 3608 GN=HIM_03366 PE=4 SV=1
---------------------------------------R-SAVVLTGAGLSVASGLADYRGTNGTYRLNK---T-----Y--RPIYYYEFLEARKRSLH
--KASPNAGHYAVRDLGD-LG-INSVITQNVDSFHPKAHPIPSLELHGYLRATVCTSCRSEFPWDELLRQYPPCPRCLADGILKPAVVMFGEIATQVSAA
EEAIDGAGKLLVLGTSLATYSAWRLAKRAKDRGMPIAIVNMGGVRGEEHFFADVHPKTDEFLPALVSELRK--------
>tr|T5AAK6|T5AAK6_OPHSC Silencing information regulator OS=Ophiocordyceps sinensis (strain Co18 / CGMCC 3.14243) GN=OCS_05515 PE=4 SV=1
---------------------------------------P-SAVVLSGAGLSVASGLADYRGVKGTYRVNK---S-----Y--RPIYYAEFLDARKRSLH
--KASPNAGHYALGDIGD-LG-IRSVITQNVDSLHPKAHPIPSLELHGYLRSTVCTSCRGEYSWAQLLQQYPPCPRCLTNGILKPAVVMFGEIAAPVMAA
EEAIDGAGKLLVLGTSLATYSAWRLAKRAKDRGMPMAIVNLGGVRGEDSFFTELSPATDQLLPALVSELGK--------
>tr|A0A086T1L0|A0A086T1L0_ACRCH NAD-dependent protein deacetylase-like protein OS=Acremonium chrysogenum ATCC 11550 GN=ACRE_060230 PE=4 SV=1
---------------------------------------P-STLVLSGAGLSVASGLADYRGPKGTYRVNK---S-----Y--RPIYHHEFLNARKRSLH
--KAVPNPGHYAIKHLGE-LG-VRSVITQNVDSFHPKAHPVPTLELHGYLRSTVCTTCRTEFPWAALLKEYPPCPKCLSHGILKPAVVMFGEIAGSVTAA
EQAVDSAGKLLVLGTSLATYSAWRLAKRANDRGMPMAIINMGGVRGEDQFFTNLSPATHELLPALVSHLRQ--------
>tr|A0A0D9NSI5|A0A0D9NSI5_METAN Uncharacterized protein OS=Metarhizium anisopliae BRIP 53293 GN=H634G_07847 PE=4 SV=1
---------------------------------------D-STVVLTGAGLSVASGLADYRGVKGTYRVNK---T-----Y--RPIYYYEFVGARKRTLH
--KATPNAGHYAIRDLGN-LG-IRSVITQNVDSFHPKAHPIPSLELHGYLRSTVCTSCKTEFSWAALLEEYPPCPKCLADGILKPAVVMFGEIARHVAAS
EDAIDGAGRLLVLGTSLATYSAWRLAKRAKDRGMPIAIVNMGGVRGEDRFFTDLDPLTDQLLPGLVSRLRQ--------
>tr|A0A0L0NDG2|A0A0L0NDG2_9HYPO NAD-dependent protein deacetylase SIR4 OS=Tolypocladium ophioglossoides CBS 100239 GN=TOPH_03190 PE=4 SV=1
---------------------------------------T-STVVLTGAGLSVASGLADYRGPNGTYRVNK---T-----Y--RPIYHYEFLGARKRSLH
--KASPNAGHYAIRDLGE-LG-IRTVITQNVDSFHPEAHPIPTLELHGYLRATVCTSCRREFPWADLLREYPACPRCLADGILKPAVVMFGEIASNVTAA
EQAIDSAGRLLVIGTSLATYSAWRLAKRAKDRGMPIAIVNMGGVRGEEQFFADLDPSTDQLLTELVSELRK--------
>tr|A0A063C9G4|A0A063C9G4_9HYPO Silencing information regulator OS=Ustilaginoidea virens GN=UV8b_1295 PE=4 SV=1
---------------------------------------K-STVVLTGAGISVASGLADYRGVRGTYRVNK---S-----Y--RPIYHYEFVSARKRTLH
--KAVPNAGHYAVRDLGK-LG-IHSVITQNVDSFHSKAHPIPSLELHGYLRCTICTSCKTEFSWATLLEEYPPCPKCLLDGILKPAVVMFGEIASHVAAA
EDAIDNAGKLLVLGTSLATYSAWRLAKRAKDRGMPIAIVNMGGVRGEDIFFADLDPSTDQLLPALVSQLRR--------
>tr|G3JQ38|G3JQ38_CORMM Sir2 family transcriptional regulator, putative OS=Cordyceps militaris (strain CM01) GN=CCM_07541 PE=4 SV=1
---------------------------------------SSKTLILTGAGLSVASGLPDYRGVHGTYRVNK---S-----Y--RPIFYHEFLASRKRATH
--NAAPNVAHYAVRDMGA-LG-LSGVVTQNVDSFHPRAHPMPTVELHGYLRTVVCTSCRSELDWKAFMEEYPPCPKCLENGILKPNVVMFGEIATSVDAA
EAAVNASARLLIMGTSLATYSAWRLARQAKARGMPIAIINAGGVRGEDQFFADLDPMTNEILPALVEELRK--------
>tr|A0A0B7JYD1|A0A0B7JYD1_BIOOC Uncharacterized protein OS=Bionectria ochroleuca GN=BN869_000004314_1 PE=4 SV=1
---------------------------------------SPKTVVLTGAGLSVASGLADYRGVKGTYRVNK---T-----Y--RPIYYHEFLSARKRSLH
--KAAPNLGHFAVRDLSS-LG-VRSVITQNVDSFHSMAHPVPTLELHGYLRSTVCTTCRSEFSWAALLQEYPPCPKCLERGILKPAVVMFGEIASHVDNA
EKAVDQAGKLLVLGTSLATYSAWRIAKRAKDRGMPIAIINMGGVRGEEQFFTDLDPSTDELLPQLVSELRQ--------
>tr|A0A0G0AE24|A0A0G0AE24_TRIHA Uncharacterized protein OS=Trichoderma harzianum GN=THAR02_04607 PE=4 SV=1
---------------------------------------H-STVVLTGAGLSVASGLADYRGPNGTYRVNK---T-----Y--RPIYYNEFVQARKRSLL
--KAKPNSGHYAIRDLGQ-LG-ISAVITQNVDSFHHIAHPIPSLELHGYLRSTKCTTCHTEYSWAALLEEYPPCPRCLADGVLKPNVVMFGEIPTHVTAA
EDAVDNAGKLLVLGTSLATYSAWRLAKRAKERGMPIAIVNMGGVRGEDQFFEDVDPSTDDLLPTLVSQLRQ--------
>tr|G9NUL6|G9NUL6_HYPAI Uncharacterized protein OS=Hypocrea atroviridis (strain ATCC 20476 / IMI 206040) GN=TRIATDRAFT_299367 PE=4 SV=1
---------------------------------------H-SAVVLTGAGLSVSSGLPDYRGINGTYRVNK---T-----Y--RPIYYNEFTQARKRSLL
--KANPNTGHYAIRDLGE-IG-ISAVITQNVDSFHPRAHPVPSLELHGYLRSTKCTACHTEYPWAALLQEYPPCPRCLADGILKPNVVMFGEIPSHVTAA
EDAVDNAGKLLILGTSLATYSAWRLVKRAKDRGMPIAIVNMGGVRGEDQFFADLDPSTDEVLPALVSQLRQ--------
>tr|A0A024S277|A0A024S277_HYPJE Silencing information regulator OS=Trichoderma reesei RUT C-30 GN=M419DRAFT_38017 PE=4 SV=1
---------------------------------------S-STVVLTGAGLSVASGLADYRGPNGTYRVNK---T-----Y--RPIYYNEFVQARKRSLQ
--KAKPNAGHYAIRDLGD-LG-ISAVITQNVDSFHPKAHPIPSLELHGYLRSTSCTTCRTEYPWADLLQEYPPCPRCLADGVLKPNVVMFGEISNHVSAA
ENAIDSAGRLLVLGTSLATYSAWRLAKRAKDRGMPIAIVNMGGVRGEDQFFVDVNPSTDDLLPALVSQLRQ--------
>tr|F0XAD7|F0XAD7_GROCL Sir2 family histone deacetylase OS=Grosmannia clavigera (strain kw1407 / UAMH 11150) GN=CMQ_3300 PE=4 SV=1
---------------------------------------PQATVAITGAGLSVASGLADYRGANGTYRVNK---T-----Y--RAIYHHEFIAARKRTLR
--KAAPNAAHYAVRDLGR-LG-LHAVVTQNVDSFHRLAHSPATVELHGYLRATVCTSCFREFSWAAFLVEYPACPHCLAQGILKPAVVMFGEIAPAVHAA
EAAVDQAGRLLVLATSLATYSAWRLAKRARDRGMPIAIVNMGGVRGEEAFFDSVGLSTDSLLPMLVDELQR--------
>tr|A0A0D2IP33|A0A0D2IP33_9EURO Uncharacterized protein OS=Fonsecaea multimorphosa CBS 102226 GN=Z520_05222 PE=4 SV=1
---------------------------------------RNKTVLLTGAGISVASGLADYRGVNGTYTQNK---N-----Y--RPIYYHEFISSRKRGLH
--RSKPNAGHYAIRDLGK-LGLVDRVVTQNVDSFHGLAHPLKTVELHGFLRALVCLSCRRLIDWAEFLQQYPACPHCLKRGVLKPNVIMFGEISADVTAA
EEAIDSAAKILVVGSSLATYSAWRLVKRAHERGMGIGILNMGGVRKEEVFFGDLLPPAEEILPAVVDAIRA--------
>tr|A0A0D1YTF2|A0A0D1YTF2_9EURO Uncharacterized protein OS=Exophiala sideris GN=PV11_01549 PE=4 SV=1
---------------------------------------SDKTVLLTGAGISVASGLADYRGQNGTYTQNK---S-----Y--RPVYYHEFVASRKRGLH
--RSKPNATHYAIRDLGQ-LGFVNNVVTQNVDSFHSLAHPLPTVELHGFLRALVCLSCRKLMDWATFLQEYPACPSCLKRGILKPNVIMFGEIPASVAEA
EAAIDGASKILILGSSLATYSAWRLVKRAHEQGMGIGILNMGGVRKEEAFFGDYQTPSEEVLPAVVEQLRQ--------
>tr|A0A0D2BUF9|A0A0D2BUF9_9EURO Uncharacterized protein OS=Exophiala xenobiotica GN=PV05_04804 PE=4 SV=1
---------------------------------------TNKTVLLTGAGISVASGLADYRGPNGTYTQNK---S-----Y--RPIYYHEFVASRKRGLH
--RSQPNDTHYAIRDLGR-LGCVDTVITQNVDSFHPLAHPLPTVELHGFLRSLICLSCKTLMDWAAFLQDYPACPSCLRRGVLKPNVIMFGEIPAPVAAA
EAAIDAASRILVVGSSLATYSAWRLVKRAHERGMGIGILNMGGVRKEEAFFGDYHHPAEEVLPAVVECIRL--------
>tr|A0A0D2DZT0|A0A0D2DZT0_9EURO Uncharacterized protein OS=Exophiala oligosperma GN=PV06_01218 PE=4 SV=1
---------------------------------------GNKTVLLTGAGISVASGLADYRGQNGTYTQNK---N-----Y--RPIYFHEFVAARKRGLH
--RSSPNATHFAIRDLGR-LGLVDSVITQNVDSFHRLAHPLHTVELHGYLRSLVCLSCKNLMDWAAFLQEYPACPTCLKRGVLKPNVIMFGEIPASVTEA
EAAIDAASKILVVGSSLATYSAWRLVKHAHERGMGIGILNMGGVRKEELFFGEHRHPAEEILPAVVDLVQE--------
>tr|S3BRX9|S3BRX9_OPHP1 Sir2 family protein OS=Ophiostoma piceae (strain UAMH 11346) GN=F503_01493 PE=4 SV=1
---------------------------------------PSSTVVLTGAGLSVASGLADYRGDNGTYRINK---T-----Y--RPIYFHEFVAARKRTLH
--KAKPNASHYALRDLGR-LG-VQSIITQNVDSFHRIAHPTSTVELHGYLRSAVCTTCHGEVPWAEFLYEYPPCPHCLANGILKPAVVMFGEISPAVHAA
EGAIDQAGRLLVLATSLATYSAWRLATRAKDRGMPIGIVNMGGVRGEDVFFAGIDPATDAVLPPLVEELQK--------
>tr|A0A0C2EZ94|A0A0C2EZ94_9PEZI SIR2 family histone deacetylase OS=Sporothrix brasiliensis 5110 GN=SPBR_01758 PE=4 SV=1
---------------------------------------PSSTVVLTGAGLSVASGLADYRGENGTYRVNK---T-----Y--RPIYFHEFLAARKRTLH
--EAKPNTSHYALRDLGR-LG-VHSVITQNVDSFHHAAHPPSTVELHGYLRATVCTTCYREYPWAEFLADYPPCAHCLANGILKPAVIMFGEISPSAHAA
EAAVDGAGRLLVLATSLATYSAWRLAKRAKDRGMPIAVVNMGGVRGEDAFFADLDDPTDAVLPPLVDELHR--------
>tr|A0A0B0EGC1|A0A0B0EGC1_NEUCS DHS-like NAD/FAD-binding domain-containing protein OS=Neurospora crassa GN=GE21DRAFT_1247664 PE=4 SV=1
---------------------------------------PNRTVILTGAGLSVASGLADYRGVNGTYRVNK---D-----Y--KPIFHHEFLATRQRGLG
--RAGPNPGHYAIRDLGN-LLTITGVITQNVDSFHKMSHPIQTVELHGTLASVVCTSCRNQFPWADFLREYPACPSCLKEGVLKPAVIMFGEISAEVSEA
EKAIDNAGRMLILGTSLATYSAWRLAQRAKLRGMPIAIVSIGGVRREEMFFEDLDPATEQLLPALVEELKT--------
>tr|A0A0D2IYD4|A0A0D2IYD4_9EURO Rhinocladiella mackenziei CBS 650.93 unplaced genomic scaffold supercont1.7, whole genome shotgun sequence OS=Rhinocladiella ma
---------------------------------------QNKTVLLTGAGISVASGLADYRGENGTYTQNK---S-----Y--RPIYYHEFVAARKRGLH
--RSKPNAAHFAIRDLGR-LGLVGSVITQNVDSFHPLAHPLHCVELHGFLRNLICLSCKKPMDWASFLTEYPACPSCLKRGVLKPNVIMFGEIPASVALA
EAAIDSASKILVVGSSLATYSAWRLVKRAHEQGMGIGVLNLGGVRKEEVFFGDYTHPAEEILPSVVDVIRS--------
>tr|A0A072PIH4|A0A072PIH4_9EURO Uncharacterized protein OS=Exophiala aquamarina CBS 119918 GN=A1O9_04402 PE=4 SV=1
---------------------------------------SRKTVLLTGAGLSTASGLADYRGTNGTYTQNK---T-----Y--RPIYFHEFVASRKRGLN
--RSQPNAGHKAIRDLWQ-LGLVSSVVTQNVDSFHNMAHRLRTIELHGYLRRLVCLSCRHEMDWSAFLQDYPACPTCLKRGVLKPNVIMFGEIPQATTAA
EEAIDGAAKLLVVGSSLATYSAWRLAKRALDRNMPIAILNIGGVRKEDAFFEGVERAAEDILPGVVELVRR--------
>tr|A0A0P7BBC6|A0A0P7BBC6_9HYPO Uncharacterized protein OS=Neonectria ditissima GN=AK830_g8856 PE=4 SV=1
---------------------------------------H-STVALTGAGLSVASGLADYRGVKGTYRVNK---E-----Y--RPIYYPEFLKARKRSLH
--KASPNTGHHAIRDLGQ-LG-IRSVITQNVDSFHPQAHPLPTLELHGHLRSIVCTTCTSEFSWAALLKEYPSCPKCLSNGVLKPAVVMFGEINPIIDAA
EDAIDSAGKLLVLGTSLATYSAWRLAKRAQDRGMPMAIISIGGVRGEDGFFNELDPSTDDLLPALVSELRK--------
>tr|S0E9F3|S0E9F3_GIBF5 Related to sirtuin type 4 OS=Gibberella fujikuroi (strain CBS 195.34 / IMI 58289 / NRRL A-6831) GN=FFUJ_08640 PE=4 SV=1
---------------------------------------PSSAVVLTGAGLSVASGLADYRGAKGTYKVNK---T-----Y--RPIYYPEFLKSRKRNLQ
--KASPNKGHYAIRDLAS-LGLIRSVITQNVDSFHPRAHPLPALELHGYLRAVVCTTCKNEFSWAELLEKYPSCPKCLSSGILKPAVVMFGEIDNHVHAA
EEAIDNAGKLLVVGTSLATYSAWRLAKRAQDRGMPIAIISMGGIRGEDKFFAGMDPSTDDLLPALLSALRN--------
>tr|A0A093XL47|A0A093XL47_9PEZI Uncharacterized protein OS=Pseudogymnoascus pannorum VKM F-3557 GN=V490_04825 PE=4 SV=1
---------------------------------------PNSTVILTGAGISVASGLADYRGTNGTYRVNK---T-----Y--RPIYYHEFVQARKRNLV
--RSEPNATHRAIRDLGH-MG-IKSVVTQNVDSFHLLAHPLPALELHGYLRSLRCISCHNELPWAELLEEYPACPTCLATGILKPAVVMFGEIATSVEAA
ERAIDSSGRLLILGTSLATYSAWRLARRAKDRGMPIAVVNLGGVRGEELFFEHLDASSDKLLPSLVDHLHR--------
>tr|A0A094AN30|A0A094AN30_9PEZI Uncharacterized protein OS=Pseudogymnoascus pannorum VKM F-4281 (FW-2241) GN=V493_01654 PE=4 SV=1
---------------------------------------PNSTVILTGAGISVASGLADYRGNNGTYRVNK---T-----Y--RPIYYHEFVQARKRNLD
--RAEPNATHGAIRDLGH-MG-IKNVVTQNVDSFHLVAHPLPTLELHGYLRALRCISCHSELPWAELLEEYPACPSCLATGILKPAVVMFGEIASPVEAA
EHAIDSAGRLLVIGTSLATYSAWRLARRAKDQGMPIAIINLGGVRGEELFFENLDGSSDKILPSLVDYLHS--------
>tr|A0A094D7J0|A0A094D7J0_9PEZI Uncharacterized protein OS=Pseudogymnoascus pannorum VKM F-4515 (FW-2607) GN=V496_06997 PE=4 SV=1
---------------------------------------PSSTVVLTGAGISVASGLSDYRGNNGTYRVNK---T-----Y--RPIYYHEFVQARKRNLD
--RAEPNATHRAIRDLGH-MG-IKSVVTQNVDSFHLIAHPLPALELHGYLRALRCISCHNELPWAELLEEYPACPTCLSTGILKPAVVMFGEIASSVEAA
EHAIDSAGKLLVVGTSLATYSAWRLARRAKDQGKPIAIVNIGGVRGEELFFDHLDGSSDKLLPSLVEHLHT--------
>tr|A0A093ZB86|A0A093ZB86_9PEZI Uncharacterized protein OS=Pseudogymnoascus pannorum VKM F-4246 GN=V492_06355 PE=4 SV=1
---------------------------------------PNSTVVLTGAGISVASGLADYRGNNGTYRVNK---T-----Y--RPIYYHEFVQARKRNLD
--RAEPNATHRAIRDLGH-MG-IKNVVTQNVDSFHLIAHPLPALELHGYLRALRCVSCHNELPWAELLEEYPACPTCLATGILKPAVIMFGEIPSPVVAA
ENAIDSAGRLLVLGTSLATYSAWRLARRAQERGMPIAIVNLGGVRGEELFFENLGGPSDKLLPTLVDHLHT--------
>tr|A0A0G2ET59|A0A0G2ET59_9EURO Putative sir2 family histone OS=Phaeomoniella chlamydospora GN=UCRPC4_g01891 PE=4 SV=1
---------------------------------------KSKTLFLTGAGLSTSSGLADYRGVGGTYTLNP---S-----Y--RPIYYHEFLESRQRTMR
--AARPNAAHHAIATLAS-AGDISAIITQNVDSFHTLAIGVPIIELHGYLRALVCITCHNHLPWARFLDEYPPCPTCLANGVLKPNVTMFGEIHPEVAAA
ENAVETVDRVLVIGSSLATYSAWRLIKRAHDLGMKIGILNLGGVRKEDGFYSEEVRKAEDILPEVVKLLGA--------
>tr|A0A0P4WM13|A0A0P4WM13_9EUCA Uncharacterized protein OS=Scylla olivacea PE=4 SV=1
-------------------------------------GKCKNIITMAGAGISTSAGIPDFRSPTGLYNNPFPEAIFDIEFFKSNPKP---FFVLAKDLYP
-GAFNPTPSHWFIRLLHEK-GILLRHYTQNIDTLEHIAGLEKVVEAHGTFRTSHCIACRKEYSWMKEIDNIPTCEECS--GLVKPDIVFFRESLPRFQLM
QTDFPKCDLLLILGTSLTVQPFAMLINNVPS-SCPRLLINREKAGAMNIRDVALLGDCDDGCVKLVDMLG---------
>tr|A0A0N7Z8L8|A0A0N7Z8L8_9HEMI Putative sirtuin 5 (Fragment) OS=Rhodnius neglectus PE=2 SV=1
-------------------------------------NQFQSVITMVGAGISTAAGIPDFRSPKGLYHNPYPQAIFELVYFLKQPEP---FFQIARELFP
-GSFHPTAAHYFLKLLQEK-GLLLRHYTQNIDNLERTAGLEKLIEAHGTFYRSHCVNCKRQYTWMKEITDVPLCESCG--CVVRPDIVFFGEALPKFNYS
AEDFGKCDLLIVMGSSLTVEPFASLVRSVKR-DCPRIVINDRPVGHTNHRDVFIEGSCDDGCRKLAATFG---------
>tr|A0A069DSW9|A0A069DSW9_9HEMI Putative sirtuin 5 (Fragment) OS=Panstrongylus megistus PE=2 SV=1
-------------------------------------QQVRYIITMVGAGISTAAGIPDFRSPKGLYHNPYPQAIFELGYFIQQPEP---FFHLARELFP
-GSFEPTVAHYFIKLLNDK-DLLLRHYTQNIDSLERTAGVDKLVEAHGTFYTSHCLNCEREYTWMKEITDVPLCEDCG--SVVKPDIVFFGEALPKFQNI
ATDFDKCDLLIIMGSSLTVEPFASLVRKVKR-NCPRIIINDRPVGHSSNRDVFIEGSCDDGCRKLADVLG---------
>tr|C1BNZ8|C1BNZ8_CALRO NAD-dependent deacetylase sirtuin-2 OS=Caligus rogercresseyi GN=SIRT2 PE=2 SV=1
-------------------------------------GKARKIITMVGAGISTSAGIPDFRTPSGLYARGNPTDLFSMNYFRMNPKP---FFKLAKDLLK
-SSFRPTPCHYFIKLLESK-GLLLRHYTQNIDTLERKAGVDLLVEAHGSFASSTCLSCGLRYDWMEKVMDVVTCEDCH--GIVKPDIVFFGESLPRFGLV
FQDFPFCDLLIIMGTSLQVQPFASLVNQVPE-TTPRLLINMEVVGNERYRDVAEIGSCDAGCSKLAEALG---------
>tr|C1BVG4|C1BVG4_LEPSM NAD-dependent deacetylase sirtuin-2 OS=Lepeophtheirus salmonis GN=SIRT2 PE=2 SV=1
-------------------------------------GKARRIITMVGAGISTSAGIPDFRTPSGLYSREDPTDLFSMGYFRTNPKP---FFQLAKDLLK
-SNYSPTPCHYFIKLLESK-GLLLRHYTQNIDCLERKAGVDLLVEAHGSFASSTCQLCGSRYDWMEKLVDVVCCSGCG--GVVKPDIVFFGESLPRFNLV
FQDFPYCDLLIIMGTSLQVQPFASLVNQVQD-TTPRLLINMQVVGDERYRDVAEIGTCDDGCKKLAEALG---------
>tr|C1C279|C1C279_CALCM NAD-dependent deacetylase sirtuin-2 OS=Caligus clemensi GN=SIRT2 PE=2 SV=1
-------------------------------------GKAQRIITMVGAGISTSAGIPDFRTPSGLYSRGDPTDLFSMNYFRANPKP---FFQLAKDLLK
-TNYIPTPCHYFIKLLESK-GLLLRHYTQNIDTLERKAGVELLVEAHGSFASSTCLHCGWRYDWMEKVMEIVFCEGCG--GVVKPDIVFFGESLPRFRLV
FQDFTSCDLLIIMGTSLQVQPFASLVNRVRD-TTPRLLINMEVVGDGRYRDVAEIGKCDDGCKKLAEALG---------
>tr|A0A0N4V5P7|A0A0N4V5P7_ENTVE Uncharacterized protein OS=Enterobius vermicularis PE=4 SV=1
-------------------------------------NKANRVIVMCGAGISTSAGIPDFRSPSGLYDNPDPLAVFDINFFRQKPEP---FFAVARKLFP
-ENLKPTPCHYFIRLLDQK-GVLRRCFTQNIDSLEYVSGLERIVTAHGSYHTGRCLSCNKKYTWMRALDNCKVFRSCK--GIVKPDIVFFGENLPRFRCA
ATDFPQCDLLIIMGTSLVVQPFAGMVNEVGK-NVPRLLINLTEAGNKNYRDVFWKGTCDDGVM----------------
>tr|A0A0L8IAL6|A0A0L8IAL6_OCTBM Uncharacterized protein OS=Octopus bimaculoides GN=OCBIM_22024899mg PE=4 SV=1
-------------------------------------DKCKNIITMAGAGLSTSAGIPDFRSPSGLYDNPHPQAIFEINFFRECPEP---FFKLVKNMWP
-SDLKPTPSHYFLKLLDEK-GLLLRHFTQNIDGLERMAGIEKIVEGHGTFQTSHCINCKAEYDWIKEIDEIPHCTECK--GLVKPDIVFFGEHLPKFA-V
QKDFKNCDLLIILGTSLTVMPFAALVSMVPN-STPRLYINLTKDNESN-RDVFWQGTCDDGCEKLAELLD---------
>tr|M7B6Q0|M7B6Q0_CHEMY NAD-dependent deacetylase sirtuin-2 OS=Chelonia mydas GN=UY3_15080 PE=4 SV=1
-------------------------------------EKCRNVVCIVGAGISTSAGIPDFRSPTGLYANPYPEAIFEINYFKQHPEP---FFALARELYP
-GQFKPTVCHYFIRLLKEK-GLLLRCYTQNIDTLERVAGLEDLVEAHGTFFTSHCLSCKKKYTWMKEITVTPKCDKCQ--SLVKPDIVFFGENLPRFTLM
QSDFQKVDLLIIMGTSLQVQPFASLVSRVPT-NTPRLLINKEKTGQVAYQDVAWLGECDQGCTALAELLG---------
>tr|U3EQS2|U3EQS2_MICFL NAD-dependent deacetylase sirtuin-2-like protein OS=Micrurus fulvius PE=2 SV=1
-------------------------------------EKCKNIVCMVGAGISTSAGIPDFRSPTGLYANPYPEAIFEIGYFKQNPEP---FFTLARELYP
-GQFKPTVCHYFIRLLKDK-GLLLRCYTQNIDTLERVAGLEHLVEAHGTFYTSHCISCRMSYSWMKEISVTPRCEKCQ--SVVKPDIVFFGENLPRFSLM
QSDFQNADMLIIMGTSLQVQPFASLVSRVPT-NTPRLLINKEKTGE-AY-DVAWLGDCDEGCLALAELLG---------
>tr|K8F9W3|K8F9W3_9CHLO NAD-dependent deacetylase sirtuin-2 OS=Bathycoccus prasinos GN=Bathy10g02400 PE=4 SV=1
-------------------------------------DACKNIVVMCGAGVSVSAGIPDFRTPTGLYDNPYPQAVFEIGFFKSNPEP---FYLLASHLQP
-GKFEPTKTHKFIKLLETK-KKLRRCFTQNIDSLETKAGVEKVVAAHGNFDTARCLHAQD---KVMEVGAPM--RQCE--EYVKPDIVFFGENLPRFKLA
KVDFNNCDLLIVMGTSLQVQPFAGLIEYPDI-DCPRILINREKVGEV-GRDVLFLGDCDEGVRQLCEHLE---------
>tr|F4WSY1|F4WSY1_ACREC NAD-dependent deacetylase sirtuin-1 OS=Acromyrmex echinatior GN=G5I_09047 PE=4 SV=1
----------------------------TLSDVVRLIRSSKKIIVLTGAGVSVSCGIPDFRSRDGIYSRPDPQAMFDIDYFSQDPRPFYKFA---REIY-
PGQFKPSPCHRFIKMLEKQ-KKLLRNYSQNIDTLEQVAGIENVIECHGSFATASCTKCKYQVRANEDIQRIPTCPKCRSQGIMKPDIVFFGEGLPAFHDA
MKDKDDCDLLIVIGSSLKVRPVALIPSSIP-SHVPQILINREPLPH-LKFDVELLGDGDIIINQICHLMGDTYEEV---
>tr|A0A0K8TSH7|A0A0K8TSH7_TABBR Putative nad-dependent histone deacetylase sir2-like protein (Fragment) OS=Tabanus bromius PE=2 SV=1
----------------------------TVSDVVRLLRNSKNIIVLTGAGVSVSCGIPDFRSIDGIYSRPDPQAMFDIQYFSKDPRPFYKFA---KEIY-
PGQFTPSACHRFIKLLEKK-KKLLRNYTQNIDTLERIAGIENVIECHGSFATASCTKCNFKTSADDDIQRIPLCPICHQSGIMKPDIVFFGEGLPAFHSA
MIDKDKCDLLIVIGSSLKVRPVALIPSSIP-ADVPQILINREQLCH-LQFDVELLGDSDVIINQLCHLLGNDWTEI---
>tr|A0A060W009|A0A060W009_ONCMY Uncharacterized protein OS=Oncorhynchus mykiss GN=GSONMT00078134001 PE=4 SV=1
----------------------------TLEDVVRILHESKKILVLTGAGVSVSCGIPDFRSRDGIYARPDPQAMFDIEYFRRDPRPFFKFA---KEIY-
PGQFQPSPCHKFISMLGKH-GKLLRNYTQNIDTLEQVAGVQRIIQCHGSFATASCLICKHKVDCEEDIQVVPHCPRCRPLAIMKPDIVFFGENLPLFHRA
MQDKDEVDLLIVIGSSLKVRPVALIPTSIP-HEVPQVLINREQLPH-LNFDVELLGDCDVIVNELCHRLGGDFEQL---
>tr|W5U624|W5U624_ICTPU NAD-dependent protein deacetylase sirtuin-1 OS=Ictalurus punctatus GN=Sirt1 PE=2 SV=1
----------------------------TIEDVIRLLNDCKKILVLTGAGVSVSCGIPDFRSRDGIYARPDPQAMFDIEYFQRDPRPFFKFA---KEIY-
PGQFRPSLCHRFIAMLDKK-EKILRNYTQNIDTLEQVAGVQRVMQCHGSFATASCLVCKHKVDCDEDIQVVPHCPRCHPFAIMKPDIVFFGENLPAFHRA
MQDKDEVDLLIVIGSSLKVRPVALIPSSVP-PEVPQVLINREPLLH-LNFDVELLGDCDVIVNELCHRLGGDFEQL---
>tr|A0A0C9QA08|A0A0C9QA08_9HYME SIRT1 protein (Fragment) OS=Fopius arisanus GN=SIRT1 PE=4 SV=1
----------------------------TLNDVVRLIKDSKKIIILTGAGVSVSCGIPDFRSRDGIYSRPDPQAMFDINFFAQDPRPFFKFA---REIY-
PGLFKPSPCHRFIKMLEKH-KKLLRNYSQNIDTLEQVAGIENVIECHGSFATASCTKCKFQVTAETDIQRIPLCPKCSSLGIMKPDIVFFGEGLPAFHDS
IKDKDECDLLIVIGSSLKVRPVALIPSSIP-SHIPQILINRESLPH-LKFDVELLGDGDIIINQLCHLMGEEFLQL---
>tr|K7IZZ5|K7IZZ5_NASVI Uncharacterized protein OS=Nasonia vitripennis GN=LOC100122518 PE=4 SV=1
----------------------------TMSDVVELIKNSKNIIVLTGAGVSVSCGIPDFRSRDGIYSRPDPQAMFDINYFSQDPRPFFKFA---REIY-
PGQFKPSPCHQFIKMLEKQ-KKLLRNYSQNIDTLERVAGINNLIECHGSFATASCTKCKYQVKSDAEIQTIPMCPKCQAQGVMKPDIVFFGEGLPAFHDA
MSDKDVCDLLIVIGSSLKVRPVALIPSSIP-SHVPQILINRESLQH-LEFDVELLGDGDVVINQLCHMLDGSFKEV---
>tr|A0A067QLW9|A0A067QLW9_ZOONE NAD-dependent deacetylase sirtuin-1 OS=Zootermopsis nevadensis GN=L798_15407 PE=4 SV=1
----------------------------TLVDVVRLLKGANKIIVLTGAGVSVSCGIPDFRSRNGIYSRPDPQAMFDIQYFSQDPRPFFKFA---REIY-
PGQFKPSPCHRFIKMLEKH-KKLLRNYSQNIDTLEQVAGIQNVIECHGSFATASCTRCKHKVTADEDIQGIPVCPCCPSRGIMKPDIVFFGEGLPVFHES
MKDKDECDLLIVIGSSLKVRPVALIPSSIP-PDVPQILINREPLPH-FSFDVELLGDSDVIINQICHMMGNKWTEV---
>tr|D6WFJ9|D6WFJ9_TRICA Putative uncharacterized protein OS=Tribolium castaneum GN=TcasGA2_TC002584 PE=4 SV=1
----------------------------TLDDVVRLVKGAQNIIVLTGAGVSVSCGIPDFRSRDGIYVRPDPQAMFDISYFSQDPRPFFKFA---RDIY-
PGKFTPSPCHRFIKMLENY-GKLLRNYTQNIDTLEKVANIEKVIECHGSFATATCTKCGHKVTADEIVQQIPLCEKCHSSGIMKPDIVFFGEGLPTFHEA
MQDKTECDLLLVIGSSLKVRPVALIPSSLP-PHVPQILINREPLPH-CHFDVELLGDCDVIVNHLCHLFGGVWKEG---
>tr|V5GRI9|V5GRI9_ANOGL NAD-dependent protein deacetylase sirtuin-1 (Fragment) OS=Anoplophora glabripennis GN=SIRT1 PE=4 SV=1
----------------------------TLDDVVRLLKGAQNIIVLTGAGVSVSCGIPDFRSRDGIYSRPDPQAMFDISYFSQDPRPFFKFA---KDIY-
PGKFQPSPCHRFIKLLEKH-GKLLRNYTQNIDTLEKVAKIERVIECHGSFATATCTKCSHKVTADDTVQKIPSCEVCHASGIMKPDIVFFGEGLPTFHEA
MVDKSQCDLMLVIGSSLKVRPVALIPSSLP-SHVPQILINREPLPH-CHFDVELLGDCDVIINHLCRLLGNMWEEG---
>tr|W8CBS6|W8CBS6_CERCA NAD-dependent protein deacetylase sirtuin-2 OS=Ceratitis capitata GN=SIRT2 PE=2 SV=1
--------FSRLALHPDQSSKVIPD--LSFDGFLSHWKGFKKIVTMVGAGISTSAGIPDFRTPGGLYDNPHPTDIFELDYFIENPKP---FYALAKELY-
PGNFRPTPVHYFIRLLNEK-NLLVRHYTQNIDSLERLAGLEKMVEAHGTFHTNHCLECGLEFSWMKEIDTIPLCDACN--GIVKPDIVFFGEGMPFYDMP
AEDFKNCDLLIVMGTSLEVYPFASLVGHAEP-NCLRVLINRTSIDPTNKRDINFIGDCDDAVWKMAEAL----------
>tr|A0A0A1X192|A0A0A1X192_BACCU NAD-dependent deacetylase sirtuin-2 OS=Bactrocera cucurbitae GN=SIRT2 PE=4 SV=1
--------FSRLSVHQHEHDTVIPN--LTFEGFLKHWKGFKKIITLVGAGISTSAGIPDFRTPGGLYDNPHPTDIFELDYFLENPKP---FFSLAKELY-
PGNFIPTPTHYFIRLLNDK-GLLVRHYTQNIDSLERIAGIDKMVEAHGTFHTNHCLECTTLYSWMKEIDTIPLCDHCA--GIVKPDIVFFGENMPFYNMP
TEDFKDCDLLFVMGTSLEVYPFASLVGYAEP-TCLRVLINRTSVNPVNKRNITYVGDCDDAVWKITDAL----------
>tr|A0A0K8VP96|A0A0K8VP96_BACLA NAD-dependent deacetylase sirtuin-2 OS=Bactrocera latifrons GN=sirt2_0 PE=4 SV=1
--------FSRLSVHQEPATGVIPS--LTFDGFLQHWKGFRKIITLVGAGISTSAGIPDFRTPGGLYDNPHPTDIFELDYFLDNPKP---FFSLAKELY-
PGHFTPTPTHYFIRLLNDK-GLLVRHYTQNIDSLERIAGIEKMVEAHGTFHTNHCLECTTLYSWMKDLDTLPLCDHCG--GIVKPDIVFFGENMPFYNMP
TEDFKDCDLLFIMGTSLEVYPFASLVGYAEP-SCLRVLINRNVVGPVNKRDISYVGDCDDAVWKIAEAL----------
>tr|A0A0N4TSP9|A0A0N4TSP9_BRUPA Uncharacterized protein OS=Brugia pahangi PE=4 SV=1
--------MTKLEKEKEKDKQKLSS--LTIEGIAEYIREVKNIIVLTGAGISTSAGVPDFRSPGGLYDNPDPMAIFDISYFKKHPEP---FYKLAKDLF-
PSHLKPTPCHYLIRLMDEK-GLLLRWYTQNIDSLEFVTGIDKLVTAHGCHHTSTCLSCRAKFDWIMNVVKVAHCDKCG--GIVKPDIVFFGENLPFFNYS
IRDFPKCDLLIIMGTSLVVHPFAGLVDEVND-DVPRLLINLTEAGKDNYRDVFWQGTTDDGAWKLAELL----------
>tr|A0A0N5D4N1|A0A0N5D4N1_THECL Uncharacterized protein OS=Thelazia callipaeda PE=4 SV=1
--------ISKFGNDKPNLRQKLSS--LTIEGVVEYILNIKNIIVLTGAGISTSAGVPDFRSPGGLYDNSNPMLIFDISYFMKNPEP---FYKLAKNLF-
PTNLKPTPCHYLIRLMDEK-GLLLRWYTQNIDSLEFMTGIEKLVAAHGCHHSSTCLSCYAKYDWIMNLVNVAYCEKCG--GIVKPDIVFFGENLPFFSCS
KKDFPKCDLLIIMGTSLVVQPFAGLLDAVKE-EVPRLLINLTEVGEDNYRDVFWRGTTDDGAWKLAELL----------
>tr|A0A0K0CWV5|A0A0K0CWV5_ANGCA Uncharacterized protein OS=Angiostrongylus cantonensis PE=4 SV=1
--------FSRYIHEGRCLKYKLRS--FSLEGIAEYIKRPCNVIVMSGAGISTSAGVPDFRSPGFF-------------------------------AF-
VFIFKPTLCHYFVRLLDKK-GILRRWFTQNIDSLEFLTGIDKVVTAHGSCRTSTCITCGKKFDWLTNLGLVPRCDKCE--GVVKPDITFFGENLPFFQCV
LSDFPKCDLLLIMGTSLVVQPFASLVNEVAE-DIPRLLINKEEVGKDNKRDVFWGGSCDDGCKRLAELL----------
>tr|W2T0E9|W2T0E9_NECAM Transcriptional regulator, Sir2 family OS=Necator americanus GN=NECAME_12546 PE=4 SV=1
--------------EGHCGKSKLKT--FSLEGIADFIKRPNNIIVMTGAGISTSAGIPDFRSPGGLYDNPDPQAVFDISFFHENPEP---FFALSKELF-
PETLKPTPCHYFIKLLNKK-GILRRWFTQNIDSLEFLTGVDKIVTAHGSHRTSTCLRCHKKYDWLTELCLVPKCDKCE--GVVKPDITFFGENLPFFQCA
ISDFPKCDLLLIMGTSLVVQPFASMVNEVSE-EVPRLLINKEEAGKDNKRDVFWRGSCDDGCRKLAELL----------
>tr|U6P404|U6P404_HAECO NAD-dependent histone deacetylase domain containing protein OS=Haemonchus contortus GN=HCOI_00711200 PE=4 SV=1
--------------EGHCVKSKLKS--FTLEGIADFIKHPSNVVVMTGAGISTSAGIPDFRSPGGLYNNPDPQAVFDISFFHENPEP---FFALSKELF-
PENLKPTPCHYFVRLLEKK-GILRRWFTQNIDSLEFLTGIEKVVTAHGSHRTSTCTQCSKKFDWLEDLCLVPRCDKCE--GVVKPDIIFFGENLPFFQCA
ISDFPKCDLLLIMGTSLVVQPFASLVNEVSQ-DVPRLLINKEQAGKENRRDVFWSGACDDGCRRLAELL----------
>tr|B4KGM7|B4KGM7_DROMO Uncharacterized protein OS=Drosophila mojavensis GN=Dmoj\GI18096 PE=4 SV=1
-------------EPKRRTKLSNVNTF---DDVIDLVHKSERIIVLTGAGVSVSCGIPDFRSTNGIYARPDPQAMFDINYFKRDPRP---FYKFAREIY-
PGEFKPSPCHRFIKMLETK-GKLLRNYTQNIDTLERVAGIQRVIECHGSFSTASCTKCKYKCNADADIQRIPVCPQCQPNGIMKPDIVFFGEGLDEYHTV
MTDKDKCDLLIVIGSSLKVRPVAHIPSSIP-ASVPQILINREQLH-HLKFDVELLGDSDVIINQICQRLSG--------
>tr|A0A0M4EFZ8|A0A0M4EFZ8_DROBS Sir2 OS=Drosophila busckii GN=Dbus_chr2Lg1565 PE=4 SV=1
-------------EPRRRIKLETVNTF---DDVITLVRKSQRIIVLTGAGVSVSCGIPDFRSTNGIYARPDPQAMFDINYFKRDPRP---FFKFAREIY-
PGEFSPSPCHRFIKMLEIK-GKLLRNYTQNIDTLERVAGIKRVIECHGSFSTASCTRCRYKCNAEADIQRIPVCPRCQPRGIMKPDIVFFGQGLDEYHNV
MTDKDRCDLLIVIGSSLKVRPVAHIPSSIP-PNVPQILINREQLP-HLKFDVELLGDSDVIISQICHRMAA--------
>tr|A0A0A1XKX9|A0A0A1XKX9_BACCU NAD-dependent deacetylase sirtuin-1 OS=Bactrocera cucurbitae GN=SIRT1 PE=4 SV=1
-------------EPPRRQKLRYINTF---EDVIQLIQQSRNIIVLTGAGVSVSCGIPDFRSSDGIYSRPDPQAMFDINYFSRDPRP---FFKFAREIY-
PGQFKPSPCHRFIKLLEGK-QKLLRNYTQNIDTLEQVAGIKNVIECHGSFSTASCTKCKVKCTADEDIQRIPVCRRCQPNGIMKPDIVFFGEGLEEFHTV
MSDKDKCDLLIVIGSSLKVRPVALIPSSIP-ANVPQILINREQLH-HLEFDVELLGDSDVIINQLCHRLGD--------
>tr|A0A0G4IQM3|A0A0G4IQM3_PLABS Uncharacterized protein (Fragment) OS=Plasmodiophora brassicae GN=PBRA_000852 PE=4 SV=1
--------------IQARVKLNDVNTL---DDACDLIRKSSNIIVLSGAGVSVSCGIPDFRSKNGIYARPQPESMFDIRLFRENPDIFYSFAH---ELF-
PGRFQPSLTHHFISLLERR-GKLLRNYSQNIDDLEHYACISKVYQCHGSFATASCVTCMHQVPGDEAIRRKPLCPMCHGFGVMKPDIVFFGEPLQEFDNL
STDLPKVDLVIVVGSSLVVHPVASVIGLLE-PHIPIVLINREVVGH-PH------------------------------
>tr|I1FPN8|I1FPN8_AMPQE Uncharacterized protein OS=Amphimedon queenslandica GN=LOC100639948 PE=4 SV=1
--------------PPARELLDHVTKI---DDVVSLIQKSKNIIVLSGAGISVSCGIPDFRSPEGLYSQPDPQAMFDIQFFKVDPRPFFSFAK---EIY-
PGTYKPSPSHRFVKLLEER-GKLLRNYTQNIDTLEESAEIKRVIYCHGSFSTASCTKCKHKIEIGEEIEMIPYCPVCPAVGIMKPDIVFFGEGLESFHDQ
QQDKTEVDLLIVIGSSLKVRPVSLIPELLP-PDVPRVLINREPLQY-IQ------------------------------
>tr|H2AQ13|H2AQ13_KAZAF Uncharacterized protein OS=Kazachstania africana (strain ATCC 22294 / BCRC 22015 / CBS 2517 / CECT 1963 / NBRC 1671 / NRRL Y-82
------------------------------KVLSDKVKPNAKVIFMVGAGISTSCGIPDFRSPTGLYSNLYAEAIFDIEFFEDNPLP---FYTLATELY-
PGKFKPSKFHYLLKLFQEK-KILKRVYTQNIDTLEQEAGIDIIIEAHGNFAKNHCIKCRKEFDMDVGRCDFVKCDECD--GLIKPNIVFFGENLPFFDDD
LSLLSSEYIIIVAGTSLAVYPFASLPEEVPT-DIPRALINLETVGDPRKTDILFEGTTDDAAQLLAEELG---------
>tr|C5DXC7|C5DXC7_ZYGRC ZYRO0F03960p OS=Zygosaccharomyces rouxii (strain ATCC 2623 / CBS 732 / NBRC 1130 / NCYC 568 / NRRL Y-229) GN=ZYRO0F03960g PE=4 
------------------------------RSVSKHLQPDAKVIFMVGAGISTPCGIPDFRSPTGLYSNLFPEAVFDVDYFEENPKP---FYTLAKELY-
PGNFKPSKFHYLMKLFEDK-GRLRRIYTQNIDTLEREAKIKYIVEAHGSFASNVCIGCSQRFPVETIEFDYARCDKCD--SLIKPSIVFFGEGLPFFDED
LEWLKGKHLVIVAGTSLSVYPFASLPSEVPL-GFKRVLWNYEVVGEPRGGDLVFKGGSDEAAQELAKELN---------
>tr|S6EUU7|S6EUU7_ZYGB2 ZYBA0S09-00606g1_1 OS=Zygosaccharomyces bailii (strain CLIB 213 / ATCC 58445 / CBS 680 / CCRC 21525 / NBRC 1098 / NCYC 1416 / N
------------------------------KKVAEHLKSDAQVIFMVGAGISTPCGIPDFRSPTGLYSNLFPEAVFDIDYFEENPKP---FYTLARELY-
PGNFKPSRFHYLMKVFEEK-GRLHRVYTQNIDTLEREATIKYLVEAHGSFASNECISCSKSYSVDRIEFEYALCDKCD--SLVKPSIVFFGESLPFFEKD
LEWLKKKNLVIVVGTSLSVYPFASLPSEVPS-EVPRVLWNYEVVGDPRSSDVIFKGSSDEAAEELAMEMG---------
>tr|G8ZR49|G8ZR49_TORDC Uncharacterized protein OS=Torulaspora delbrueckii (strain ATCC 10662 / CBS 1146 / NBRC 0425 / NCYC 2629 / NRRL Y-866) GN=TDEL0
------------------------------KKFADHLKPDAKVIFMVGAGISTSCGIPDFRSPTGLYHNLFAEAVFDVDYFEENPKP---FYTLAQELY-
PGTFQPSRFHNLMKLFEDK-KRLQRVYTQNIDTVEHQALIEYVIEAHGSFASNHCIKCAKKYPLEKPEFDYARCDECD--GLVKPAIVFFGEGLPFFEQD
QQWLLKRHLVMVVGTSLTVYPFASLPQEVPE-TVLRALINKELVGDPREKDIIFHGEADLAAELLAEEMG---------
>tr|A7TQV8|A7TQV8_VANPO Putative uncharacterized protein OS=Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294) GN=Kpol_1011p1 PE=4 SV=1
------------------------------TVLANHLKPDSKVIFLVGAGASTSCGIPDFRSPTGLYHNLYAEAVFDVDYFKENPKP---FYTLAKELY-
PGNFKPSEFHYLMKLFEDK-GRLKRIYTQNIDTLEREAGIELVIEAHGSFASNHCIECAKEFPLSVGEFSYAKCSECK--GLIKPKIVFFGENLPFFDDD
VEWLSTEDLIIVAGTSLTVHPFASLPSEVPD-TSRRGLFNLGLVGDPRDDDIFIEGLLDEIAHKLATELG---------
>tr|A0A090BBT2|A0A090BBT2_KLUMA NAD-dependent deacetylase HST2 OS=Kluyveromyces marxianus GN=KMAR_20204 PE=4 SV=1
------------------------------KTLAKYLKPEAKAIFMVGAGISTSSGIPDFRSPTGLYHNLYAEAVFDIDYFKKDPKP---FYTLAEELY-
PGNFKPSPFHCLMKLFEEK-GRLKRIYTQNIDTLEREAKIEYIVEAHGSFASNHCVECGKEFPRETEEELYAKCDECD--GLVKPKIVFFGEGLPFFDLD
SSLEDEKIVCIVGGTSLSVFPFASLPMEAPE-GWQRVLINREVVGDRRSSDLIYQGSTDDAAFLLASELG---------
>tr|Q6CKF6|Q6CKF6_KLULA KLLA0F11033p OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) GN=KLLA0_F11033
------------------------------KKLAKYLQPDVKVIFMVGAGISTSSGIPDFRSPTGLYHNLYAEAVFDIEYFEQNPKP---FYTLAKELY-
PGNFKPSPFHYLMKLFESK-NRLKRIYTQNIDTLEREANIEFIIEAHGSFASNHCIDCGKEFPKEADGGNYATCDGCG--GLIKPKIVFFGEGLPFFDLD
SSTK-EKTVCIVCGTSLTVYPFASLPMEAPN-SWLRVLLNREIVGDRQDTDLIFKGSADYAAFLLAQELC---------
>tr|M9N598|M9N598_ASHG1 FAGL018Cp OS=Ashbya gossypii (strain FDAG1) GN=FAGOS_FAGL018C PE=4 SV=1
------------------------------NKVAKYIKPKAKVVFLVGAGISTSCGIPDFRSPTGLYHNLYAEAVFAIDYFQRDPKP---FYTLAREMY-
PGKYIPSRFHYLMKLFESK-GYLKAVYTQNIDTLEREAGIDYIIEAHGSFATNHCIDCDKTFPTET-SGEYARCEDCE--GLIKPRIVFFGEDLPFYDKL
LSEMQEDYLVIVAGTSLVVYPFASLPSETPR-KVHRVLMNMEVVGDPRKTDIIIHGETDHIAEELARALG---------
>tr|A0A0A8LAB3|A0A0A8LAB3_9SACH WGS project CCBQ000000000 data, contig 00015 OS=Kluyveromyces dobzhanskii CBS 2104 GN=KLDO_g4055 PE=4 SV=1
------------------------------KKLSECLNPDVKVIFMVGAGISTSSGIPDFRSPTGLYHNLYAEAVFDIDYFEKNPKP---FYTLAKELY-
PGNFKPSPFHYLMKLFENK-NRLKRIYTQNIDTLEREAEIEFIIEAHGSFAANHCIDCDKEFPREV-EGKYALCDNCG--GLIKPKIVFFGEGLPFFDLD
SSAK-EKTVCIVCGTSLTVFPFASLPAEAPN-SWIRALLNREIVGDRKKNDLIFQGSADEAAFLLAQELN---------
>tr|A0A0D4XB14|A0A0D4XB14_YEASX Hst2p OS=Saccharomyces cerevisiae YJM195 GN=HST2 PE=4 SV=1
------------------------------RKIAAHMKPNAKVIFMVGAGISTSCGIPDFRSPTGLYHNLYPEAVFDVDFFQSDPLP---FYTLAKELY-
PGNFRPSKFHYLLKLFQDK-DVLKRVYTQNIDTLERQAGVDLIIEAHGSFAHCHCIGCGKVYPPQVPIKDFVKCDVCG--ELVKPAIVFFGEDLPFSLND
SEWLRQRPLVIVVGTSLAVYPFASLPEEIPR-KVKRVLCNLETVGDKRPTDLIVHQYSDEFAEQLVEELG---------
>tr|Q6FKU1|Q6FKU1_CANGA Uncharacterized protein OS=Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) GN=HST2 PE=4 SV=1
------------------------------KVVAEHLKPSSKVIFLVGAGISTSSGIPDFRSPTGLYHNLYAEAVFDIEYYQENPQP---FYLLADELY-
PGNFKPSKFHYLMKVLEKN-GRLRRVYTQNIDTLEREAGIDYLVEAHGSFAKNHCIGCDKEFPLDDKEFEYLRCPECE--ALIKPKIVFFGENLPFFDTD
LEWLE-NSIVIVAGTSLTVYPFASLPNDVPN-NVRRVLCNLDVVGDPRDMDLKFSEHTDDFANQLVKELG---------
>tr|I2H319|I2H319_TETBL Uncharacterized protein OS=Tetrapisispora blattae (strain ATCC 34711 / CBS 6284 / DSM 70876 / NBRC 10599 / NRRL Y-10934 / UCD 7
------------------------------TQIVEHLNPESKVIFMVGAGISTSCGIPDFRSPTGLYHNLYAEAVFDIEYYKKNPKP---FYILANELY-
PGKFKPSKFHYLMKLFQDK-NRLQRIYTQNIDTLEREAGISYVIEAHGSFAENECIECKKKYPLKVKKFKYARCDNCN--GLIKPKIVFFGENLPFFDED
LELLNSNDIVIVAGTSLTVYPFASLHEEIPK-AIKRILINFDKAGQPRNTDLFFKGSSDDAAVELVQNLN---------
>tr|A0A0L8RAS1|A0A0L8RAS1_SACEU HST2-like protein OS=Saccharomyces eubayanus GN=DI49_5441 PE=4 SV=1
------------------------------KKIAAHLKPGAEVIFMVGAGISTSCGIPDFRSPTGLYHNLYPEAVFDVDFFQSNPLP---FYTLAKELY-
PGNFEPSKFHHFLKLFQDR-NLLRRIYTQNIDTLERQAGIDLVIEAHGSFAHCHCIECGKIFPQHVPIKDFVKCDACD--ELIKPAIVFFGEDLPFSSKD
SKWLRQEPLVIVVGTSLAVYPFASLPEEIPR-KVKRVLCNLETVGDKRPTDLVVNLYSDAFAEQLVEELG---------
>tr|J4TXD6|J4TXD6_SACK1 HST2-like protein OS=Saccharomyces kudriavzevii (strain ATCC MYA-4449 / AS 2.2408 / CBS 8840 / NBRC 1802 / NCYC 2889) GN=YPL015
------------------------------RAIAAHLKPSAKVIFMVGAGISTSCGIPDFRSPTGLYHNLYPEAVFDVDFFQSDPLP---FYTLAKELY-
PGTFKPSKFHHLLRLFQDK-NLLRRVYTQNIDTLERQAGVDLIIEAHGSFAHCHCIGCGKIYPPQGPIRNFARCEVCN--ELIKPAIVFFGEDLPFSSSD
SEWLRQQPLVIVVGTSLAVYPFASLPEEVPR-KVKRVLCNLETVGDKRSTDLIVNQYSDAFAEQLVEELG---------
>tr|B6JXE7|B6JXE7_SCHJY Sir2 family histone deacetylase Hst2 OS=Schizosaccharomyces japonicus (strain yFS275 / FY16936) GN=SJAG_01075 PE=4 SV=2
------------------------------KNVADDIKKYKNICVMVGAGISTAAGIPDFRSPTGIYHNLYAEAIFDLEYFRENPKP---FFELAYELM-
PGRYMPTPTHYFLRLMNEK-GLMLRCFTQNIDTLERIAGVDKIVEAHGSFQYNRCIECKEMADSGYETKDVPLCEKCK--GYVKPTIVFYGEGLPFFYED
ME---KCDLALVIGTSLLVHPFADLPEIATE-NCQRLLINREVVGD-RESDLMVLGDCDALVRQLCKYLD---------
>tr|S9RA35|S9RA35_SCHOY Sir2 family histone deacetylase Hst2 OS=Schizosaccharomyces octosporus (strain yFS286) GN=SOCG_01215 PE=4 SV=1
------------------------------EKVASLIKKVNQICVMVGAGISTAAGIPDFRSPTGIYNNLYAEAVFDLSYFRKNPRP---FYELAYELM-
PEKFRPTYTHYFIRLLHDK-GLLKRCYTQNIDTLERLAGIDLLVEAHGSFQYSRCIECYEMSDTEYKQKQVPQCVHCK--GFVKPMITFYGEGLPFFEDD
TT---NCDMALVLGTSLLVHPFAELPEIVPD-SCERVLINREIAGD-RKNDTIVLGDCEVHIRSLCEMLG---------
>tr|C0S0X1|C0S0X1_PARBP Uncharacterized protein OS=Paracoccidioides brasiliensis (strain Pb03) GN=PABG_01236 PE=4 SV=2
----------------------------------IKEKNVRRIVVLTGAGISTAAGIPDFRSPDGIYANPHPEAVFDISYFRKNPRP---FYSLSKEMF-
PGRYRPTIAHTFIKLLYDK-GLLLKLFTQNIDCLERQAGVGMIVEAHGSYATHSCIDCKSPYPDDLESNDIPLCLKCC--GFVKPDIVFFGESLPSFFMN
RTLTTAAELCIIMGTSLTVQPFASLPSLCK-EGVPRLLINLNRVGGSRPDDVLLLGECDDGVLKLADAL----------
>tr|C4JFD5|C4JFD5_UNCRE Putative uncharacterized protein OS=Uncinocarpus reesii (strain UAMH 1704) GN=UREG_00949 PE=4 SV=1
----------------------------------IKEKDVKKIVVMVGAGISTAAGIPDFRSPDGIYANPTPEAVFDIEYFRTDPRP---FYALTKEML-
PGKAKPTLTHSFIKLLYDK-GRLLKLFTQNIDCLEREAGIEMIVEAHGSFATQSCIECKSPYPADLEANDVPLCPGCL--NLVKPDVVFFGEPLPTFLLN
RTLPAAADLCIVMGTSLTVRPFSSLPSLCR-DETPRILINLTQAGGSRPDDVLVLGECDDGVMKLAEAL----------
>tr|A0A0J6I2G8|A0A0J6I2G8_COCPO NAD-dependent deacetylase sirtuin-2 OS=Coccidioides posadasii RMSCC 3488 GN=CPAG_01876 PE=4 SV=1
----------------------------------IHEKNARKIVVLVGAGISTAAGIPDFRSPDGLYANPTPEAVFDIQYFRTDPRP---FYALTKEML-
PGKCKPTITHSFIKLLYNK-GRLLKLFTQNIDCLEREAGIEMIVEAHGTFATQSCIECKTPYPGELEANDVPLCPECM--NLVKPDVVFFGEALPSFFLN
RTLPAAADLCIVMGTSLSVQPFSSLPSLCR-EGIPRLLINLTQAGGSRPDDVLLLGECDDGVMKLADAL----------
>tr|A0A0G2IBK7|A0A0G2IBK7_9EURO NAD-dependent histone deacetylase SIR2 OS=Emmonsia crescens UAMH 3008 GN=EMCG_06247 PE=4 SV=1
----------------------------------IKEKNVRRIVVLTGAGISTAAGIPDFRSPDGVYANPDPEAVFDISYFRKNPRP---FYALSKEMF-
PGRYRPTLTHSFIKLLYDK-GRLLKLFTQNIDCLEREAGVEMIVEAHGSYASHRCIDCKASYPDDLDADDVPLCLECQ--GLVKPDIVFFGEPLPVFFMN
RTLTAAADLCIIMGTSLSVHPFASLPSLCR-EGCPRLLINLNRVGGTRPDDVLLLGECDDGVLKFAEAL----------
>tr|W6QK36|W6QK36_PENRO NAD-dependent deacetylase, sirtuin family OS=Penicillium roqueforti FM164 GN=PROQFM164_S05g000194 PE=4 SV=1
----------------------------------VKQHNVKKVVVMVGAGISTSAGIPDFRSPDGIYANPEPEAVFDIGFFRRNPKP---FYALAHELY-
PGRYRPTVVHSFIKLLYEK-GMLLKHFTQNIDCLEREAGVDKIIEAHGSFASQRCIECKETFPDEEAKSNVPHCHKCN--GLVKPDIVFFGESLPEFFES
RSLPEEADLCIVMGTSLSVQPFASLPSMVS-PGVPRVLINMERVGGSRSDDVLVIGDCDAGVRKFAKAL----------
>tr|S4RPQ6|S4RPQ6_PETMA Uncharacterized protein (Fragment) OS=Petromyzon marinus PE=4 SV=1
-------------------------------------GKCKNIVCMVGAGISTAAGIPDFRSPTGLYDNLHPQAVFDIGYFRENPEP---FFALAKELY-
PGQFKPTVSHYFIRLLKDK-ECLLRCYTQNIDTLERVAGLNELVEAHGTFHTSHCLGCRHEYCWMKEIDKVPRCEKCK--SVVKPDIVFFGEALPKFTCV
QSDFPKCDLLIIMGTSLVVQPFASLTSRVPD-STPRLLINLEKSGQCDYRDVAWLGTCDDGCLEFAELL----------
>tr|Q68BG1|Q68BG1_CHICK NAD-dependent deacetylase SIRT2 OS=Gallus gallus GN=sirt2 PE=2 SV=1
-------------------------------------ERCRRVVCMVGAGISTAAGIPDFRSPTGLYANLYPEAIFDISYFKQHPEP---FFALAKELL-
PGQLKPTVCHYFMRLLKEK-GLLLRCYTQNIDTLERVAGLEELVEAHGTFQTAHCLRCRHQYDWVKEISLVPKCDKCQ--SVVKPDIVFFGENLPRFSLL
QSDFQKVDLLIIMGTSLQVQPFASLVSRVPA-STPRLLINKEKTGQSDYRDVAWLGDCDEGCLALAELL----------
>tr|H9GFI4|H9GFI4_ANOCA Uncharacterized protein OS=Anolis carolinensis GN=SIRT2 PE=4 SV=2
-------------------------------------EKCKNVVFMVGAGISTAAGIPDFRSPTGLYANLYPEAIFEINYFKKHPEP---FFALARELY-
PGQFKPTVCHYFMRLLKEK-GLLLRCYTQNIDTLERVAGLEDLVEAHGTFFTSHCISCKKMYSWMKEISLIPKCEKCQ--SVVKPDIVFFGENLPRFSLM
QSDFQNVDLLIIMGTSLQVQPFASLVARVPT-NTPRLLINKEKTGESDYRDVAWLGDCDEGCYALAEFL----------
>tr|K7IUV9|K7IUV9_NASVI Uncharacterized protein OS=Nasonia vitripennis GN=LOC100123744 PE=4 SV=1
-------------------------------------HNVKKIVTMAGAGISTSAGIPDFRSPSGLYHNLHPQAIFELDFFKSNPEP---FFVLAKELL-
PEGYKPTPSHYFIRLLHEK-GLLLRHYTQNIDTLERLAGLEKLVEAHGTFHSGRCLDCQASFDWMKEIATVPKCEECE--GVVKPDIVFFGEMLPRHRLI
DQDFPEAELLIIMGSSLLVQPFASLVDRVKR-SCPRLLINKEKVGMQD-RDVALLGECDKGCQLLAEKL----------
>tr|A0A022T3S8|A0A022T3S8_9HYME NAD-dependent deacetylase sirtuin-2-like protein OS=Microplitis demolitor GN=K425_1138 PE=4 SV=1
-------------------------------------NNCRNIITMAGAGISTSAGIPDFRSPSGLYYNLYPQAIFEIDFFKSNPEP---FFVLAKELF-
PEKLKPTLSHCFIKLLSDK-GLLLRHYTQNIDTLERISGLEKLVEAHGTFHSSRCLECRTIYDWLKKVETIPKCEKCE--GVVKPDIIFFGEMLPRYQSI
EHDFPKADLLIIMGSSLVVQPFASLIDKVKS-SCPRLLINKEKVSVQDERDVAWIGDCDKGCKLLADKL----------
>tr|V4B5Z2|V4B5Z2_LOTGI Uncharacterized protein OS=Lottia gigantea GN=LOTGIDRAFT_206064 PE=4 SV=1
-------------------------------------KKCKNIITMAGAGISTSAGIPDFRSKTGLYDNLCPEAIFTIDYFKENPEP---FFVLAKELF-
PGKFKPTPCHYFIRLLHDK-GLLLRHYSQNIDTLERVAGLEKLVEAHGTFHSSHCLICDKQYTWIKEIDTIPKCDECD--GVVKPDIVFFGEALPRAECY
AEDFGKCDMLIVMGTSLKVQPFASLTSRVPV-ECPRLYINLEKTDDSSYRDVFKQSTCDDGCLELADKI----------
>tr|A0A026W657|A0A026W657_CERBI NAD-dependent deacetylase sirtuin-2 OS=Cerapachys biroi GN=X777_09767 PE=4 SV=1
-------------------------------------KESCKIITMAGAGISTSAGIPDFRSPSGLYHKLHPQAIFELDFFMKNPEP---FFTLARELL-
PEGFKPTLSHYFIRMLWEK-GLLLRHYTQNIDTLERVAGLDKLVEAHGTFHTGRCLKCRAPYTWMKEIGVIPKCEECE--GVVKPDIVFFGEMLPRQMLA
DRDFEQADLLIIMGSSLVVQPFASLIDRVRS-TCPRLLINNEKVGMQDYRDVAWLGTCDTGCQLLADKL----------
>tr|A0A0C9R9B4|A0A0C9R9B4_9HYME Sirt2 protein OS=Fopius arisanus GN=Sirt2 PE=4 SV=1
-------------------------------------TGCKKIITMAGAGISTSAGIPDFRSPSGVYSNLHPQAIFDIDYFAENPEP---FFALAKLLL-
PEGYKPTPSHYFVRLLWEK-GLLLRHYTQNVDTLERIAGLEKLVEAHGTFHTGRCLKCRCPYDWMKEIGPIPKCEECE--GVVKPDIVFFGEMLPRHTLI
EHDFVRADLLIIMGSSLVVQPFASLIDRVPS-TCPRLLINREKVGLQDERDVAWVGDCDTGCELLAEKL----------
>tr|H2NYQ5|H2NYQ5_PONAB Uncharacterized protein OS=Pongo abelii GN=DKFZP468D2219 PE=4 SV=1
-------------------------------------ERCRRVICLVGAGISTSAGIPDFRSPTGLYDNLYPEAIFEISYFKKHPEP---FFALAKELY-
PGQFKPTICHYFMRLLKDK-GLLLRCYTQNIDTLERIAGLEDLVEAHGTFYTSHCVSCRHEYPWMKEIEVTPKCEDCQ--SLVKPDIVFFGESLPRFSCM
QSDFLKVDLLLIMGTSLQVQPFASLISKAPL-STPRLLINKEKAGQSDYRDVAWLGDCDQGCLALAELL----------
>tr|H0VIX1|H0VIX1_CAVPO Uncharacterized protein OS=Cavia porcellus GN=SIRT2 PE=4 SV=1
-------------------------------------ERCRRVICLVGAGISTSAGIPDFRSPTGLYANLYPEAIFEITYFKKHPEP---FFTLAKELF-
PGQFKPTVCHYFIRLLKEK-GLLLRCYTQNIDTLERVAGLEDLVEAHGTFYTSHCTSCRHEYTWIKELDVTPKCEKCQ--SVVKPDIIFFGENLPRFSYM
QSDFRKVDLLIIMGTSLQVQPFASLIGKAPL-STPRLLINKEKAGQTDYRDVAWLGDCDQGCLALADLL----------
>tr|A0A059LPP4|A0A059LPP4_9CHLO Sir2 family protein OS=Helicosporidium sp. ATCC 50920 GN=H632_c396p1 PE=4 SV=1
-------------------------------------GKAKNIVVMCGAGMSVSAGIPDFRTPTGLYARLHPQAIFEIDYFRRTPQP---FFHLARHLF-
PGTYLPTPAHHFLVLLHAK-GLLTRIYTQNIDSLEVQAGLSVVVPAHGNFDSARCIDCRAPHEHVRDVEGVARCSNCN--GLVKPDIVMFGEDLPRFELL
KVDFPKADLLIVLGTSLIVHPFASLIDHVKL-DVPRVLINREVVGEPDHRDVLMLGDCDDGCRELARLL----------
>tr|Q5U250|Q5U250_XENLA Sir2 protein OS=Xenopus laevis GN=sirt2 PE=2 SV=1
-------------------------------------EKCKNVICMVGAGISTSAGIPDFRSPSGLYSNLYPEAIFQIGYFKENPEP---FFALARELF-
PGQFKPTICHYFMRLLKEK-GLLLRCYSQNIDTLERVAGLEDLVEAHGTFYSSHCVGCGAEYSWMKEIDLIPKCEKCN--NLVKPDIVFFGESLPRFSAV
KSDFPKVDLLIVMGTSLQVQPFASLVSKVSS-KTPRLLINKELTGQGDYRDVAWLGDCDDGCLALADFL----------
>tr|H2ZEV4|H2ZEV4_CIOSA Uncharacterized protein OS=Ciona savignyi GN=Csa.1012 PE=4 SV=1
-------------------------------------DKCKNIIVMSGAGISTAAGIPDFRSPSGLYDNLNPQAIFEINFFKKNPQP---FYTLAKELY-
PGNFKPTTSHYFIKLLEQK-GLLKRAYTQNIDTLERVAGVDKLVEAHGTFHTSHCVDCAKEFSWVKDIDEIPRCESCE--NLVKPDIVFFGEALPRFELR
FDDFESCDLLIIMGTSLKVHPFASLVGGVKD-TTPRLLINREKCGEIDYRDVCWLGNCDDGCLALADLL----------
>tr|V9KYZ6|V9KYZ6_CALMI NAD-dependent deacetylase sirtuin-2 OS=Callorhinchus milii PE=2 SV=1
-------------------------------------GKCNRIICIVGAGISTSAGIPDFRSPTGIYDNLYPEAIFEIDYFKKHPKP---FFELAKELF-
PSQLKPTICHYFIRMLRDK-KLLLRCYTQNIDTLERVVGLRHLIEAHGTFYRSHCVNCMKKYDWMKDIQTIPFCQNCY--SLVKPDIVFFGEGLPKFEAM
QMDFPSCDLLMIMGTSLQVQPFASLVNRVPR-STPRLYINKERFPKKDYRDVAYIGLCDDGCLDLAELL----------
>tr|A0A0C9XS58|A0A0C9XS58_9AGAR Unplaced genomic scaffold K443scaffold_10, whole genome shotgun sequence OS=Laccaria amethystina LaAM-08-1 GN=K443DRAFT_128922 
-----------------RDKLPQYNTI---ADAIQLIRQSQRIVILTGAGISVSCGIPDFRSRNGLYASYDPQQMFDINYFREHPS---AIY--------
PANFVPSPCHRFIKLIEDQ-GK---NYTQNIDTLETLAGVQRVLQCHGSFATASCLLCRRRVPGLTDIQKVPLCTVCNAPGIMKPDITFFGEKLDEFDHY
AEDRDKVDLLLVIGTSLNVSPVAEILSHLP-HSIPQILINKTPIRHI-NPDIVLLGNADEIVEYLCTELAW--------
>tr|A0A0D7AM85|A0A0D7AM85_9AGAR SIR2-domain-containing protein OS=Fistulina hepatica ATCC 64428 GN=FISHEDRAFT_69437 PE=4 SV=1
-----------------REKLPNYNTI---EDALQLIRQSRRIILLTGAGISVSCGIPDFRSRDGLYASYDPQQMFDIQYFKQNPKYPSQIY--------
PSNFVPSPCHRFIKLLEDK-DKLLRNYTQNIDTLETLAGVTRVIQCHGSFATASCIQCRRRVQGSREIRKVPLCKSCNPPGIMKPDITFFGEKLDDFDHA
DGDRDQVDLLIVIGTSLKVAPVADLITHLP-HSVPQILINRTPIRHI-NPDIVLLGNADTVIEYLCERLDW--------
>tr|A0A0C3Q8G0|A0A0C3Q8G0_9HOMO Uncharacterized protein OS=Tulasnella calospora MUT 4182 GN=M407DRAFT_30332 PE=4 SV=1
-----------------RTKLPQYNTV---DDSRAEYVR--PFLRSNNWGLKVFPPTADFRSANGLYAAYDPQQMFDINYFKEHPEVFSQIY--------
PSNFIPSPCHRFIKLLEDR-AVLLRNYTQNIDTLESKLGVQKVLRCHGSFATASCLQCRRKVPGTDAIKEIPICSVCKATAIMKNDITFFGEAVDDFDKY
LEDHGKVDLLLVIGTSLKVAPVSELLTHLP-HS---ILINKTPVPHV-NTDIVLLGDADAVVKYLCSRLRW--------
>tr|A0A0L6WPE9|A0A0L6WPE9_9AGAR NAD-dependent histone deacetylase sir2 OS=Termitomyces sp. J132 GN=J132_05510 PE=4 SV=1
-----------------RDKLTPYNTI---SDAVNLIRSSRRILILTGAGII-----------------------FYTH-------SNSQMY--------
PSNFVPSPCHRFIKLIEDK-GQLLRNYTQNIDTLETLAGVQRVLQCHGSFATASCLQCRRRVPGFADIQRVALCTMCTPPGIMKPDITFFGEKLDEFDNA
AEDREHVDLLLIIGTSLKVSPVAEILSHLP-HSVPQILINKTPIRHI-NPDIVLLGNADDIVQYLCDALGW--------
>tr|A0A0C2TFE9|A0A0C2TFE9_AMAMU Uncharacterized protein OS=Amanita muscaria Koide BX008 GN=M378DRAFT_76769 PE=4 SV=1
-----------------RDKLPQYNTI---DDAVQLIHNSSRILILTGAGISVSCGIPDFRSKNGIYATYDPQQMFDISYFRESPRFSTDIY--------
PSNFVPSPCHRFIKLMEDK-GKLLRNYTQNIDTLETAAGVQCVLQCHGSFASASCLQCCRRVPGSGDIHQVPLCTVCNTPGIMKPDITFFGEKLDEFDRS
EADRERVDLLLIIGTSLKVAPVADILTHLP-HSVPQILINKTPIRHV-NPDIVLLGSADDIMLHFCNKLGW--------
>tr|A0A0D2Q2F0|A0A0D2Q2F0_9AGAR Uncharacterized protein (Fragment) OS=Hypholoma sublateritium FD-334 SS-4 GN=HYPSUDRAFT_1068851 PE=4 SV=1
-----------------RDKLPQYNTI---ADAVQLIHQSRRILILTGAGISVSCGIPDFRSRDGLYASYDPQQMFDINYFKENPSVFSQIY--------
PSNFVPSPCHRFIKAVEEH-QKLLRNYTQNIDTLETLAGVQKVLQCHGSFAMASCLQCRNRVPGTGDIQKVPLCKLCNTPGIMKPDITFFGEKLDEFDHS
AEDRFKADLLLIIGTSLKVSPVAEITSHLP-HSIPQILINKTPIRHI-NPDIVLLGNADDIVLHLTNELGW--------
>tr|A0A0C3GBW2|A0A0C3GBW2_9HOMO Uncharacterized protein OS=Piloderma croceum F 1598 GN=PILCRDRAFT_814025 PE=4 SV=1
-----------------REKLPNYNTI---TDAVSLIRESQRIVILTGAGISVSCGIPDFRSQNGIYASYDPQQMFDIQYFKENPSVTRQIY--------
PSNFIPSPCHRFIKLVEDK-NKLLRNYTQNIDTLETLAGVSRVLQCHGSFATASCINCRRRVPGSNDIQKVPLCPACNAPGIMKPDITFFGEKLDNFDHA
LEDREKVDLLLVIGTSLNVAPVADVVSHLP-HSVPQILINKTPVRHI-NPDIVLLGNADDIVHYLCKELGW--------
>tr|D8Q0R7|D8Q0R7_SCHCM Putative uncharacterized protein (Fragment) OS=Schizophyllum commune (strain H4-8 / FGSC 9210) GN=SCHCODRAFT_108004 PE=4 SV=1
-----------------RERLPQYNTI---DDAANLIKGAQRIMILTGAGISVSCGIPDFRSSTGLYANYDPQEMFDIHYFRENPAVFHEIY--------
PSKFVPSPCHRFIKLVEDK-GKLLRNYTQNIDTLETLAGVKRVLNCHGSFATASCIQCRRRVPGTEAIKKVPVCSVCCPTGIMKPDITFFGEKLDDFDDA
REDRDKVDLLIIIGTSLKVSPVADLIMHLP-HSVPQILINKQPVRHI-NPDIVLLGDADRIVEHLCSVLGW--------
>tr|A0A0D0CWM5|A0A0D0CWM5_9AGAR Unplaced genomic scaffold GYMLUscaffold_27, whole genome shotgun sequence OS=Gymnopus luxurians FD-317 M1 GN=GYMLUDRAFT_244490 
-----------------RDKLPQYNTI---ADAVDLIRNGKRILILTGAGISVSCGIPDFRSRNGLYAQYDPQQMFDINYFRENPSVFSQIY--------
PSNFVPSPCHRFIKLIEDK-GQLLRNYTQNIDTLETLAGVERVLQCHGSFATASCLLCRRKVPGSSDIRKVPLCSVCNPPGIMKPDITFFGEKLDNFDRS
EEDRENVDLLLVIGTSLKVAPVADILSHLP-HSVPQILINKTPVKHI-NPDIILLGNADDIILHLCGALGW--------
>tr|A0A0H2S4L0|A0A0H2S4L0_9HOMO SIR2-domain-containing protein OS=Schizopora paradoxa GN=SCHPADRAFT_918787 PE=4 SV=1
-----------------RERLQQYSTL---DDALFLLRRAQRIIVLTGAGISVSCGIPDFRSRNGLYAMYDPQQMFDITYFKEHPNVFHQIY--------
PSNFKPSPCHRFIKALEDR-EKLLRNYTQNIDTLETLTGIKRVLQCHGSFATASCINCRTKVIGTDDIKRIPLCKICNEPGIMKPDITFFGEKLDDFDDK
MEDRKLTDLLLVIGTSLKVAPVAEILTHVP-HSIPQIVINKTPIRHI-NPDIMLLGDADDIVKYLSDRLGW--------
>tr|V2X0N9|V2X0N9_MONRO Histone deacetylase OS=Moniliophthora roreri (strain MCA 2997) GN=Moror_11657 PE=4 SV=1
-----------------RERLPQYSTI---DHAVDLIRKSQRIIILTGAGISVSCGIPDFRSRNGLYASYDPQQMFDITYFKENPSVFSQIY--------
PSNFVPSPCHRFIKLVENK-E-K--NYTQNIDTLETAAGVQRVIQCHGSFATATCLLCRRRVPGKSEIRKVPLCPVCNTPGIMKPDITFFGEKLDEFDRS
EEDRHKADLLLVIGTSLKVAPVADLISHLP-HSIPQILINKTPIRHI-NPDIVLLGNADDIVIHLCERLGW--------
>tr|A0A0C3CL31|A0A0C3CL31_HEBCY Uncharacterized protein OS=Hebeloma cylindrosporum h7 GN=M413DRAFT_363794 PE=4 SV=1
-----------------RDKLSQYNTV---ADAVQLIRQSQRILILTGAGISVSCGIPDFRSRDGLYASYDPQQMFDIRYFKENPSVFSQIY--------
PSNFVPSPCHRFIKAVEDQ-GKLLRNYTQNIDTLETLAGVQRVLQCHGSFATATCLECRQRVPGTADIRKVPLCKICNTPSIMKPDITFFGEKLDDFDNS
AEDRFKVDLLLVIGTSLK------------------ILINKTPIRHI-NPDIVLLGNSDDIVLYLSRELGW--------
>tr|A0A0D0BHN1|A0A0D0BHN1_9HOMO Unplaced genomic scaffold CY34scaffold_3, whole genome shotgun sequence OS=Suillus luteus UH-Slu-Lm8-n1 GN=CY34DRAFT_797500 PE=
-----------------REKLPQYNTV---ADAVSLIQASKRVVVLTGAGISVSCGIPDFRSHNGLYATYDPQQMFDIHYFRENP-FYSQIY--------
PSNFIPSPCHRFIKAIEDR-GKLLRNYTQNIDTLETLTGITRVLQCHGSFATATCIQCRRRIPGTKDIRRVPFCTVCMQVGVMKPDITFFGEKLDDFENA
EDDRNKVDLLIVIGTSLKVSPVSEILSHLP-HSVPQILINKTPVRHI-NPDIVLLGNADDIVQHLCEQLSW--------
>tr|S7RQ65|S7RQ65_GLOTA SIR2-domain-containing protein OS=Gloeophyllum trabeum (strain ATCC 11539 / FP-39264 / Madison 617) GN=GLOTRDRAFT_138386 PE=4 S
-----------------REKLPQYNTI---DDAVELIRTSQRIIILTGAGISVSCGIPDFRSRNGLYASYDPQQMFDIHYFRENPAVFSQIY--------
PSNFTPSPCHRFIKLIEDK-NKLLRNYTQNIDTLETLAGVQKVLQCHGSFATATCLNCRLKVPGVQDIRRVPLCKVCNPPGIMKPDITFFHEKLDAFDRA
MEDRDKVDLIIIMGTSLQVAPVSETITYLP-HSVPQILINKTPIKHI-NPDIVLLGNADDIVHHLCGKLGW--------
>tr|W4K0R4|W4K0R4_9HOMO Uncharacterized protein OS=Heterobasidion irregulare TC 32-1 GN=HETIRDRAFT_387618 PE=4 SV=1
-----------------REKVPQYNTI---DDAVNLIKVSKRILILTGAGISVSCGIPDFRSENGLYANYDPQQMFDIQYFKENPSVFKQIY--------
PSNFTPSPCHRFIKLIEDK-GKLLRNYTQNIDTLETLAGVRNVLQCHGSFATASCLHCRMRMPGSTEIGEVPQCKQCSNPWIIKPDITFFGEKLDAFDDA
HVDRGEVDLILVIGTSLKVSPVSEILTNMP-HSVPQILINKTPVKHI-NPDIILLGNADPIIQYICDCLQW--------
>tr|A0A067P7E8|A0A067P7E8_9HOMO Uncharacterized protein OS=Jaapia argillacea MUCL 33604 GN=JAAARDRAFT_41808 PE=4 SV=1
-----------------RERLTRYNTV---DDAINLIRKSQRIMILTGAGISVSCGIPDFRSRDGLYATYEPTQMFDIHYFRENPSVFSQIY--------
PSNFTPSLCHRFIKLIEDK-NKLLRNYTQNIDTLETLAGVRNVLQCHGSFATASCLHCHQRVPGTDDIHRVPLCKKCNAPGIMKPDITFFHEKLDDFDHS
LEDRDKVDLLIIMGTSLQVSPVSEIISYLP-HSVPQILINKTPIRHI-NPDIILLGNADDTVKHLCSKLGW--------
>tr|F8P8I7|F8P8I7_SERL9 Putative uncharacterized protein OS=Serpula lacrymans var. lacrymans (strain S7.9) GN=SERLADRAFT_442077 PE=4 SV=1
-----------------REKLTQYNTI---SDVVSLITSSRRILVLTGAGISVSCGIPDFRSRDGL---------FDIQYFKENP-FYSQIY--------
PSNFVPSLCHRFIKLLETR-GKLLRNYTQNIDTLETLAGISRVLQCHGSFKTASCLQCRHKVPGTKDIHRVPYCDVCVAVGVMKPDITFFGEKLDEFDHA
VEDRDKVDLLLVIGTSLKVSPVSEIISHLP-HSVPQILINKTPIRHI-NPDIVLLGNADEIVHHLCEQIGW--------
>tr|A0A0C9ZDX1|A0A0C9ZDX1_9HOMO Unplaced genomic scaffold scaffold_127, whole genome shotgun sequence OS=Pisolithus microcarpus 441 GN=PISMIDRAFT_632382 PE=4 S
-----------------RERLPQYNTI---EHAVSLIQRSRRIIILTGAGISVSCGIPDFRSRNGLYASYDPQQMFDIHYFKEHP-HTSQIY--------
PSNFIPSPCHRFIKLIEDK-GKLLRNYTQNIDTLETQAGIERVLQCHGSFKTATCLLCRKQVPGVREIRRVPYCKTCLEAGVMKPDITFFGEKLDEFDRA
LEDRNKVDLLLVIGTSLKVSPVSEILSHLP-HSVPQILINRTPIRHI-NPDVVLLGNADDIVQYLCERLHW--------
>tr|A0A0C9WFW5|A0A0C9WFW5_9HOMO Unplaced genomic scaffold scaffold_10, whole genome shotgun sequence OS=Hydnomerulius pinastri MD-312 GN=HYDPIDRAFT_88766 PE=4 
-----------------REKLPQYNTI---LDAVSLISNAERIVVLTGAGISVSCGIPDFRSRNGLYAT------FDIRYFRENP-TASQIY--------
PSNFIPSPCHRFIKVIEDK-RKLLRNYTQNIDTLETQAGITRVLQCHGSFKTATCLQCQTKVPGAREIQRIPYCKACYEVGVMKPDITFFGEKLNDFDQA
IDDREKVDLLLVIGTSLKVSPVSEILSHLP-HSVPQILINKTPIRHI-NPDIVLLGNADDIVQHLCEHLKW--------
>tr|A0A0D0DP45|A0A0D0DP45_9HOMO Unplaced genomic scaffold scaffold_342, whole genome shotgun sequence OS=Paxillus rubicundulus Ve08.2h10 GN=PAXRUDRAFT_499911 P
-----------------REKLFQYNTI---SDAVSLIVNSKRIVILTGAGISVSCGIPDFRSRNGLYATYDPQQMFDIHYFRENPSVFSQIY--------
PSNFIPSPCHRFIKLLEDK-GKLLRNYTQNIDTLETLAGISRVMQCHGSFKTATCLQCRTKVPGIREIQRVPYCKLCLEVGVMKPDITFFGEKLDDFDQA
VDDRDKVDLLLVIGTSLKVSPVSEILSHFP-HSVPQILINKTPIRHI-NPDIALLGNADDIVQHLCEHLRW--------
>tr|K5XF27|K5XF27_AGABU Uncharacterized protein OS=Agaricus bisporus var. burnettii (strain JB137-S8 / ATCC MYA-4627 / FGSC 10392) GN=AGABI1DRAFT_12635
--------------------VGFYNTI---EDAVKLIQGSRRIMILTGAGISVSCGIPDFRSRDGLYASYDPQQMFDIQYFKDDPPDNSQIY--------
PSNFIPSPCHRFIKCVEDK-GKLLRNYTQNIDTLETLAGVRRVLQCHGSFATATCLQCHRKVPGTTEIRKVPLCLVCNPPGIMKPDITFFGEKLDQFDHA
IEDRNQVDLLIVIGTSLKVSPVAEIIDHIP-HSVPQILINKTPIRHI-NPDIILLGDADAIILYLCEELGW--------
>tr|A0A067SMM4|A0A067SMM4_9AGAR Uncharacterized protein (Fragment) OS=Galerina marginata CBS 339.88 GN=GALMADRAFT_79039 PE=4 SV=1
-----------------RDKLAKYNTV---SDAVDLIRKSGRILILTGAGISVSCGIPDFRSRDGLYASYDPQQMFDIQYFRENPSGYSQIY--------
PSNFVPSPCHRFIKAVEDR-GKLLRNYTQNIDTLETLAGVKTVLQCHGSFATASCLQCRQRVPGSADIHRVPLCKVCNTPGIMKPDITFFGEKLDDFDRS
AEDRWKVDLLLVIGTSLKVSPVAEILSHLP-HSIPQILINRTPIRHI-NPDIVLLGNADNIILHLCKELGW--------
>tr|A0A0D7BHY2|A0A0D7BHY2_9HOMO SIR2-domain-containing protein OS=Cylindrobasidium torrendii FP15055 ss-10 GN=CYLTODRAFT_392565 PE=4 SV=1
-----------------REKLPQYNSI---RDAVQLIQQSKRILILTGAGISVSCGIPDFRSRDGLYASYDPQQMFDITYFREKPSVFNKIY--------
PSNFIPSPCHRFIKLVEDK-GKLLRNYTQNIDTLETLTGVKTVIQCHGSFASASCIECHHKVPGKAAIRTIPLCTVCHPTGIMKPDITFFGEKLDVFDRS
EADREQVDLLLIIGTSLKVSPVADLISHIP-HSIPQILINKTPIRHI-NPDIVLLGNADAIIEHLADELNW--------
>tr|A0A060S5L7|A0A060S5L7_PYCCI Uncharacterized protein OS=Pycnoporus cinnabarinus GN=BN946_scf184851.g33 PE=4 SV=1
-----------------RERLSQYNTI---DDVVRLIQASSRILILTGAGISVSCGIPDFRSRNGLYASYDPQQMFDIEYFRENPDICSKIY--------
PSNFIPSPCHRFIKLIEDK-GKLLRNYTQNIDTLETLAGVKRVVQCHGSFATASCINCRARVPGADDIQRVPICKACNVPGIMKASG---CKKLDAFERS
MEDRHQVDLLIIIGTSLKVSPVSETI--------SKILINKTPIRHI-NPDVVLLGDADDIVKHLCRKLGW--------
>tr|A0A0C3PCB9|A0A0C3PCB9_PHLGI Uncharacterized protein OS=Phlebiopsis gigantea 11061_1 CR5-6 GN=PHLGIDRAFT_130573 PE=4 SV=1
-----------------REKQTAYNTI---DDAVDLIKQSRNIVILTGAGISVSCGIPDFRSTNGLYAQYDPQQMFDIHYFREKPSVFYQIY--------
PSNFIPSSCHRFIKLIEDK-GKLLRNYTQNIDTLETRAGVRKVLQCHGSFATASCINCKLCVPGNDDIHRVPVCKACSVPGIMKPDITFFGEKLDAFEKA
LEDRPKVDLLLVVGTSLKVSPVSEILTHLP-HSVPQILINKTPVKHI-NPDIVLLGNADEIL-----------------
>tr|S8FHT4|S8FHT4_FOMPI Uncharacterized protein OS=Fomitopsis pinicola (strain FP-58527) GN=FOMPIDRAFT_149580 PE=4 SV=1
-----------------REKLPQYNTV---DDAVRLIRERKRILVLTGAGISVSCGIPDFRSKHGLYASYDPQQMFDIHYFREKPCVIYNIY--------
PSNFTPSPCHRFIKAIEDR-GKLLRNYTQNIDTLETLAGVKRVLQCHGSFATASCLNCKVRVQGKKEIQEVPLCKLCNTPGIMKPDITFFGEKLDEFDRA
LEDRGLIDLLIIIGTSLKVSPVSDIIAHLP-HSVPQILINKTPIRHI-NPDIVLLGNADAVVTHLCRKLGW--------
>tr|K5VVB0|K5VVB0_PHACS Uncharacterized protein OS=Phanerochaete carnosa (strain HHB-10118-sp) GN=PHACADRAFT_213432 PE=4 SV=1
-----------------REKLPMYNTI---DDAVDLIKKSCHIMILTGAGISVSCGIPDFRSRNGLYAQYDPQQMFDIHYFREKPSVFSQIY--------
PSNFIPSPCHRFIKLIEEK-GKLLRNYTQNIDTLETRAGVQNVLQCHGSFATASCIDCKVTVPGNSDIHTIPVCRLCSSPGIMKPDITFFGEKLDAFEKA
IEDRPKVDLLLVIGTSLKVSPVSEILTHLR-HSVPQILINKTPVRHI-NPDIVLLGNADEIVQHLCQKLDW--------
>tr|J4H331|J4H331_9APHY Uncharacterized protein OS=Fibroporia radiculosa GN=FIBRA_04667 PE=4 SV=1
-----------------RNKISELNTI---DDAVNLIRTRKRILVLTGAGISVSCGIPDFRSRHGLYTTYDPQQMFDITYFRENPSVFSKIY--------
PSRFIPSPCHRFIKAIEDR-GKLLRNYTQNIDTLETLAGVKRVLQCHGSFATASCLNCRVRIPGVDDIHRVPLCKVCSVPWVMKPDITFFGEKLDEFDRS
LADRQEIDLLVIIGTSLKVSPVSDIIAHLP-HSVPQILINKTPVKHI-NPDIVLLGDADDIVQHLCKKIGW--------
>tr|A0A096MDG6|A0A096MDG6_POEFO Uncharacterized protein OS=Poecilia formosa PE=4 SV=1
----------------------------------INSGKCKNIICMVGAGISTSAGIPDFRSPTGLYANLYPEAIFQIDYFKKHPEP---FFALARELY-
PGQFKPTICHYFIKMLKDK-GVLRRCYTQNIDTLERVAGLDDLIEAHGTFYTSHCVKCKKEYNWMKEKDEIPKCEKCS--SLVKPDIVFFGENLPFFTSM
KMDFPRCDLLIVMGTSLQVQPFASLVGRVSK-SCPRLLINMEKTGQADYRDVAQISTCDDGCLALADLL----------
>tr|W5NAE3|W5NAE3_LEPOC Uncharacterized protein OS=Lepisosteus oculatus PE=4 SV=1
----------------------------------IQSPASKNVICMVGAGISTSAGIPDFRSPTGLYANLYPEAIFQIDYFKKHPEP---FFALARELY-
PGQFKPTVCHYFIRMLKDK-GLLRRCYSQNIDTLERVAGLDDLVEAHGTFYTSHCVSCRKEYTWMKEKDEIPKCDKCS--SLVKPDIVFFGENLPFFTSL
QMDFPRCDLLIIMGTSLQVQPFASLVGKVSA-RTPRLLINKEKTGQSDYRDVAYLGTCDDGCLALADLL----------
>tr|F1QE37|F1QE37_DANRE NAD-dependent protein deacetylase sirtuin-2 OS=Danio rerio GN=sirt2 PE=1 SV=1
----------------------------------ILSGKCKNIICMVGAGISTSAGIPDFRSPTGLYANLYPEAIFQIDYFKKHPEP---FFALARELY-
PGQFKPTVCHYFIKMLKDK-GLLRRCYSQNIDTLERVAGLEDLIEAHGTFHTSHCVSCRKEYSWMKNQEEIPKCDSCG--SLVKPDIVFFGESLPFFTSM
KADFPQCDLLIIMGTSLQVQPFASLVSRVSN-RCPRLLINMEKTGQSEYRDVAHLSTCDDGCMTLAELL----------
>tr|G3NQH4|G3NQH4_GASAC Uncharacterized protein OS=Gasterosteus aculeatus PE=4 SV=1
----------------------------------IKSGKCENIICMVGAGISTSAGIPDFRSPTGLYANLYPEAIFQIDYFKKHPEP---FFALAKELY-
PGQFKPTLCHYFIKLLKDK-GYLRRCYTQNIDTLERVAGLDDLIEAHGTFYTSHCVSCRQKYNWMRDKEDIPRCDKCK--SLVKPDIVFFGESLPFFTSM
KMDFPRCDLLLIMGTSLQVQPFAGLVGRVSK-SCPRLLINMEKAGQRICRDVAHISTCDDGCLAFAELL----------
>tr|H2LXA0|H2LXA0_ORYLA Uncharacterized protein OS=Oryzias latipes PE=4 SV=1
----------------------------------IKSGKCKNIICMVGAGISTSAGIPDFRSPTGLYANLYPEAIFQIDYFKKHPEP---FFTLAKELY-
PGQFKPTICHYFIKLLKNK-GLLRRCYTQNIDTLERVAGLEDLIEAHGTFYTSHCVSCRKEYSWMKEKDAIPKCEKCN--SLVKPGQVLIKNSFPKLCFL
WDDGISVNL--VYGFYFGLRPLGKS-SVLVM-VCPAS--------RSVFMDVAHISSCDDGCLALADLL----------
>tr|L8YHH2|L8YHH2_TUPCH NAD-dependent deacetylase sirtuin-2 OS=Tupaia chinensis GN=TREES_T100006844 PE=4 SV=1
----------------------------------M--------------QSERSAGIPDFRSPTGLYANLYPEAIFEIGYFKKHPEP---FFALAKELY-
PGQFKPTICHYFIRLLKEK-GLLLRCYTQNIDTLERVAGLEDLVEAHGTFYTSHCVSCRREYTWMKEKEVTPKCEKCQ--SVVKPDIVFFGENLPFFSCV
LQDFQKVDLLIIMGTSLQVQPFASLIGKAPL-STPRLLINKEKTGQTPYRDVAWLGDCDQGCLALADLL----------
>tr|I3L8A1|I3L8A1_PIG Uncharacterized protein OS=Sus scrofa GN=SIRT2 PE=1 SV=1
----------------------------------A--------------GISTSAGIPDFRSPTGLYANLYPEAIFEIGYFKKHPEP---FFALAKELY-
PGQFKPTICHYFIRLLKEK-GLLLRCYTQNIDTLERVAGLEDLVEAHGTFYTSHCISCRQEYTWMKVKCRVKKKRHCQ--KVMRQQCRILNPLIGDQT-V
LMDTSRVGYYIVLGATPGILGFHRPLGHSPL-VTPSLLLSFPERGKTPYRDVAWLGDCDQGCLALADLL----------
>tr|C1MPE3|C1MPE3_MICPC Histone deacetylase OS=Micromonas pusilla (strain CCMP1545) GN=MICPUCDRAFT_15302 PE=4 SV=1
----------------------------------ITSGKAKNVIVMVGAGISVSAGIPDFRTPTGLYDNLHPTAVFELDYFRENPSP---FYLLAKELY-
PGQYPPTPTHHFIHLLHKK-GILLRCFSQNIDSLEAATGLELIVPAHGNFDTARCLNGHDA-DEVRQHGIPMRCKDCD--ELVKPDIVFFGENLPFHTLA
RRDFPECDLLVIAGTSLEVHPFAGLIDFPNE-DVPRFLVNREKVGEMERRDALFLGDCDAGFAELARLL----------
>tr|A0A061S5V6|A0A061S5V6_9CHLO NAD-dependent deacetylase sirtuin 2 OS=Tetraselmis sp. GSL018 GN=SIRT2 PE=4 SV=1
----------------------------------INSGRASKVVVLCGAGISVSAGIPDFRSPTGLYENLRPEAVFDIDFFRENPRP---FYDLAKELF-
PGRFRPTPTHFFIRMLHEK-GLLLRCYTQNVDSLETQAGLEMLVAAHGNFDSSSCIKCGAAYSFTREAGTPAKCRLCR--SLVKPNIVFFGESLPFFTLC
SSDLAEADLLIVMGSSLQVQPFASLVDMVGR-RTPRLLINRERVGEGSYRDALCLGNCDDGVRELSQLL----------
>tr|L8GIH5|L8GIH5_ACACA Sitruin, putative OS=Acanthamoeba castellanii str. Neff GN=ACA1_329490 PE=4 SV=1
----------------------------------IQKGKCANIIVMCGAGISVSAGIPDFRTPTGLYYNLTPASIFDIDYFVENPEP---FYTLAKELY-
PGSYKPTVVHHFIRLLADK-GLLLRNYTQNIDGLERIAGVEKVVEAHGSFFGAHCIKCEKVHDEIRDVTDGPICDECD--GFVKPDVVFFGEPLPFHTLA
ERDFEKCDLLVVLGTSLQVQPFSKLIDKVPS-TVPRLLINRQEVGKKDARDIEFLGDCDMGIGILAELL----------
>tr|Q011Q8|Q011Q8_OSTTA NAD-dependent deacetylase sirtuin-2, sirtuin family, class I OS=Ostreococcus tauri GN=OT_ostta09g02160 PE=4 SV=1
----------------------------------VKSGRAKNVVVMTGAGISVSAGIPDFRS-SGLYARLYPQAVFELGYFKDRPGP---FYRLAKELY-
PGAFAPTPTHYFIKLLHDK-GILRRCFTQNIDSLERATGLEKVVPAHGNFDGAHCLRGHEA-DEVADAGTPMICSKCG--EYVKPDIVFFGENLPFFECA
QEDFEVCDLLIVIGTSLVVHPFAGLIERPKE-DVPRLLINMEKCGEADYRDALYLGACDDGIAELSELL----------
>tr|L8FQ89|L8FQ89_PSED2 Uncharacterized protein OS=Pseudogymnoascus destructans (strain ATCC MYA-4855 / 20631-21) GN=GMDG_05648 PE=4 SV=1
-------------------------------------GKAKRVVVLTGAGISTSAGIPDFRSPTGLYSNLYPEAVFDISFFRQNPAP---FYMLAQELY-
PGKYKPTVAHAFIALLAKK-GLLHMLLTQNIDCLERAAGVEKVVEAHGSFASQGCIDCKTEYPGEFFVGDIPYCEACG--GLVKPDITFFGESLPRFHMN
THVPAQADLMIIIGTSLSVHPFASLPDMAL-EGTPRVLLNMERVGTSRPDDVLLLGDCDGQVRRLADELG---------
>tr|W9CN03|W9CN03_9HELO Uncharacterized protein OS=Sclerotinia borealis F-4157 GN=SBOR_3764 PE=4 SV=1
-------------------------------------GKAKDIVVLTGAGISTSAGIPDFRSPTGLYANLYPEAVFDIDFFRENPAP---FYMLARELY-
PGKFYPTVSHAFLALLDKK-GLLTMLFTQNIDCLERRAGVEKVIEAHGSFASQRCIDCKTEYPEDLAVGDPASCLQCG--GLIKPDIVFFGEQLPAFHIH
KLDPATADLVIVMGTSLSVQPFATLPSLPA-EEVPRLLFNMVSVGDSRLDDVVVLGDCDSGVRKFADALG---------
>tr|A0A0K8TSI2|A0A0K8TSI2_TABBR Putative chromatin regulatory protein sir2 (Fragment) OS=Tabanus bromius PE=2 SV=1
--------------------------------------GFKKIITMVGAGISTSAGIPDFRSPGGLYHNLHPTAIFQMDYFYENPKP---FFVLAKELY-
PGSFKPTPCHYFVKLLNEK-GWLLRHYTQNIDTLERVAGIDKIVEAHGTFYTNHCLGCRKEFSMMKQIDVVPTCDKCN--GIIKPDIVFFGENLPFHDLP
SKDFRECDLLIIMGTSLEVQPFASLVDRTND-KCLRLLINREKVG-KNRTDIAWIGDCDEGVQAIADAI----------
>tr|D3TQC6|D3TQC6_GLOMM NAD-dependent histone deacetylases OS=Glossina morsitans morsitans PE=2 SV=1
--------------------------------------GFKNIITMVGAGISTSAGIPDFRSPGGLYDNLHPSAIFESHYFEQNPKP---FFALAKELY-
PGSFNPTPSHYFVRLLHEK-GLLLRHYTQNIDTLERVAGIEKLVEAHGTFYTNHCMGCDMHYSMMKQIDKLPTCTNCK--SVVKPDIVFFGENLPFYTLP
GKDFNKCDLLIIMGTSLEVQPFASLVDRAGR-RCLRLLINRTKVGGNNTRDIAYVGDCDDGVWALVGAL----------
>tr|B4NFY9|B4NFY9_DROWI Uncharacterized protein OS=Drosophila willistoni GN=Dwil\GK22445 PE=4 SV=2
--------------------------------------GFKKIVTMVGAGISTSAGIPDFRSPGGLYDNLHPTAIFDLDYFMKNPKP---FFALAKELY-
PGSFEPTPSHYFVRLLHEK-GLLQRHYTQNIDTLDQLAGIEKIVEAHGSFYLNHCLKCRKEYDMMKQIDKLPKCEKCK--GVVKPDIVFFGENLPFYSLP
DEDFKDCDLLIIMGTSLEVQPFASLIRHAGP-KCVRLLINREPVGRANIRDVGYLGDCDAGVEALAKAL----------
>tr|A0A0L0CJ84|A0A0L0CJ84_LUCCU NAD-dependent protein deacetylase Sirt2 OS=Lucilia cuprina GN=FF38_05023 PE=4 SV=1
--------------------------------------GFKNIITMVGAGISTSAGIPDFRSPGGLYDNLHPSAIFEMDYFEENPQP---FFALAKELY-
PGSFNPTPSHYFVRLLHNK-GLLLRHYTQNIDTLERIAGLDKLVEAHGTFFTNHCLGCRKLYSMMKQIDSVPTCSVCN--SVVKPDIVFFGENLPFYTLP
AKDFNKCDLLIIMGTSLEVQPFASLIDRANS-KCVRLLINRTKVG-NNTRDIAYIGDCDDGCLALAEAL----------
>tr|A0A0M4EQZ4|A0A0M4EQZ4_DROBS Sirt2 OS=Drosophila busckii GN=Dbus_chr3Rg2264 PE=4 SV=1
--------------------------------------GFKKIVTMVGAGISTSAGIPDFRSPDGLYNNLNPTAIFDVQYFENHPQP---FFELAKELY-
PGSFSPTPSHFFVRLLHEK-GLLQRHYTQNIDTLDRLAGIEKIVEAHGSFYTNHCLNCSKEYDMMKKIDELPKCEGCK--GLVKPDIVFFGENLPFYDSP
DIDFEECDLLIIMGTSLEVQPFASLIRRAGP-RCIRLLINRDAVGRPNIRDVAFLGDCDAGVRELAEAL----------
>tr|B4PP86|B4PP86_DROYA Uncharacterized protein OS=Drosophila yakuba GN=Dyak\GE25662 PE=4 SV=1
--------------------------------------GFRNIVTMVGAGISTSAGIPDFRSPGGLYSNLHPTAIFDLDYFEKNPAP---FFALAKELY-
PGSFIPTPAHYFVRLLNDK-GLLQRHYTQNIDTLDRLTGLDKIIEAHGSFHTNHCIKCRREYDMMKEIDRLPKCKKCN--GVVKPDIVFFGENLPFYTSP
DEDFQDCDLLIIMGTSLEVQPFASLVQRPGL-RCLRLLINREAVGQANTRDVAFLGDCDAGVMALAKAL----------
>tr|B4JXU9|B4JXU9_DROGR GH14148 OS=Drosophila grimshawi GN=Dgri\GH14148 PE=4 SV=1
--------------------------------------GFKKIVTMVGAGISTSAGIPDFRSPGGLYNNLHPASIFDRDYFEQNPSP---FFVLAKELY-
PGSFVPTPAHYFVRLLHDK-GLLQRHYTQNIDTLDRLTGLEKIIEAHGSFNTNHCLRCREEFDMMKKIDELPSCEQCM--GLVKPDIVFFGENLPFYTRP
EEDFDDCDLLIIMGTSLEVQPFASLIHRAGP-RCIRLLINRDAVGRSNTRDVAFLGDCDAGVLAVATAL----------
>tr|B4KA24|B4KA24_DROMO Uncharacterized protein OS=Drosophila mojavensis GN=Dmoj\GI10678 PE=4 SV=2
--------------------------------------GFKNIVTMVGAGISTSAGIPDFRSPGGLYNNLHPTAIFDVDYFQRNPTP---FFELAKELY-
PGSFEPTPAHYFVRLLHDK-GLLQRHYTQNIDTLDRLAGLHKIIEAHGSFYTNHCLNCNQEYDMMKKIDELPKCEECK--GLIKPDIVFFGENLPFYSSP
EEDFRDCDLLIIMGTSLEVQPFASLIHRAGP-RCVRLLINRDAVGRSNTRDVAYLGDCDAGVLALAEAL----------
>tr|B0XXD4|B0XXD4_ASPFC SIR2 family histone deacetylase, putative OS=Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) GN=AFUB_047930 PE=4 
------------------FRSDKMTDI---ENIANLIGQVHKIVVLVGAGISTAAGIPDFRSPTGIYDRLYPEAIFHINYFRHTPEP---FYAIARARH-
PRSLKPTITHAFLALLEKK-GLLHFVFTQNIDGLERDVGIDKILNAHGSWRTQRCWKCKTPYPDDLAIGTVPYCQDCG--GAVKPDIVFFGQPLPEFDEK
EKEVSEADMMLVMGTSLKVAPCSRLPRLAR-EGIPRVLVNREKVGDKRAEDVSILGDCDDGVRKLADALG---------
>tr|A1CD03|A1CD03_ASPCL SIR2 family histone deacetylase, putative OS=Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1
-----------------------MEEI---EKIATLIGQIRRIVVLVGAGISTAAGIPDFRSPTGIYDRLYPEAIFHINYFRHTPEP---FYAIARARH-
PRTLKPTITHAFLALLAKK-NLLHFLFTQNIDGLERDTGVNKILNAHGSWRTQHCWKCKTSYPDDLAIGVVPYCQDCG--GPIKPDVVFFGQSLPEFEDE
EKKVPEADLMIVMGTSLKVAPCSRLPGQVR-EGVPRVLINREKAGDVRPNDLCILGDCDDGVRKLADILG---------
>tr|B6H5J7|B6H5J7_PENRW Pc14g00270 protein OS=Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255) GN=Pc14g00270 PE=4 SV=1
--------------------ASMEPDI---QSIVDRIGKATRIVVLTGAGISTGAGIPDFRSPTGLYDKLYPEAIFHVNYFSHTPEP---FYAIARARH-
PGNLKPTVTHAFLALLAKK-NLLHFVFTQNIDGLEQDAGVDKVLWTHGNWKSQHCYKCKSSYPDDLAIGEVPYCLGCG--GAVKPDVVFFGQSLSEFDEK
EKEVLEADLMLVMGTSLRVAPCSRLPRLVR-RGIPRVLINNEKAGDNRDDDVCILGSCDDGVRQLADALG---------
>tr|A0A0L1JC70|A0A0L1JC70_ASPNO SIR2 family histone deacetylase OS=Aspergillus nomius NRRL 13137 GN=ANOM_002424 PE=4 SV=1
------------------PPTSQQYAL---DNIANLIEKIARIIVLAGAGISTAAGVPDFRSPTGLYDKLYPEAIFHINYFRHTPEP---FYALARARN-
PKNLKPTVSHAFLALLAKK-NLLDFVFTQNIDGLEIDAGVEKVLSCHGNWKSQRCHKCKTPYPDGLAIGQVPYCQDCG--GAVKPDVVFFGEPLPAFEVE
EKRVSDAELMLVMGTSLKVAPCSRLPRLVK-EGTPRLLVNMTQVGDTRQSDVCILGSCDDGVRRLADSLG---------
>tr|A0A0F7TXT0|A0A0F7TXT0_9EURO Uncharacterized protein OS=Penicillium brasilianum GN=PMG11_09997 PE=4 SV=1
------------------AYEIETIDL---PTIASRISQITRVVVLTGAGISTAAGIPDFRSPTGLYDKLYPEAIFHISYFSHTPEP---FYAIARARH-
PGNLKPTISHAFLALLAKK-NVLHFAFTQNIDGLEEDMGVDKILWAHGNWKSQHCWKCKAEYPDDLAIGEVPYCQECG--GAVKPNVVFFGQSLSEFDEK
QRLVPEADLMLVMGTSLKVAPCSQLPRLVK-EGTPRVLINMERAGDNRNQDVCVLGPCDDGVRKFADELG---------
>sp|P0CS88|HST22_EMENI NAD-dependent protein deacetylase hst2-2 OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) GN
------------------TQCQNQTTL---DSICKDIGKITRIVALVGAGLSTSSGLADFRTPTGLYAKLYPEALFHISYFKHTPEP---FYAIARGRH-
PWNTKPGVGHAFLALLEKK-GVLGFVFTQNIDGLELDAGVERVMNLHGDWSDQHCIKCRSSYPADRAIGEVPFCVNCE--GIVKPAIVMFGESLPGFDSR
EEELSTADLLLVIGTSLKVAPCSEIPRRLP-SHVPRVLVNRELVGNTRESDVCLLGDCDAWLREVARHLG---------
>tr|A0A0P4W4Y7|A0A0P4W4Y7_9EUCA Uncharacterized protein OS=Scylla olivacea PE=4 SV=1
---------------PRREKLRHINTI---EDVVRLIKSCRKIIILTGAGVSVSCGIPDFRSRDGIYARPDPQAMFDIHYFRRDPRPFFKFAR---EIY-
PGQFTPSLCHRFIRLIEQH-NKLLRNYTQNIDTLEQVAGITNVIQCHGSFATATCQRCGRRVDAEDDIFRIPRCSQCEGQPIMKPDIVFFGEGLDEFHDK
AEDKDECDLLIVVGSSLKVRPVALIPSSLPP-HVPQILINREPLRH-LTFDVELLGDCDVIINELCHRLDNGWE-----
>tr|V5HCG0|V5HCG0_IXORI Putative histone deacetylase silent information regulator protein sir2 (Fragment) OS=Ixodes ricinus PE=2 SV=1
---------------PRRAKLPHVNTL---DDVVHLLRSCTRILVLTGAGVSVSCGIPDFRSRDGIYARPDPQAMFDIHYFRKDPRPFFKFAK---EIY-
PGQFLPSPSHRFIKRLEES-GKLLRNYTQNIDTLEQMCGIRNVITCHGSFATASCTRCRHKVDCHDDIFRIPLCPECPPMAVMKPDIVFFGEGLPEFHQA
ARDKAECDLLIVMGSSLKVRPVALIPSSIPA-DVPQILINREPLKH-VTFDVELLGDCDVIIHELCHRLGWEVT-----
>tr|A0A087TER3|A0A087TER3_9ARAC NAD-dependent deacetylase sirtuin-1 (Fragment) OS=Stegodyphus mimosarum GN=X975_07395 PE=4 SV=1
---------------PKRSKLSHINTL---DDAVNLLRTSKRIIVLTGAGVSVSCGIPDFRSRNGVYARPDPQAMFDIHYFRRDPRPFFKFAK---EIY-
PGLFQPSPSHHFIKLLEKQ-GKLLRNYTQNIDTLEHAAGIQNVITCHGSFATATCTVCGYRVDSSDDIFRIPYCPICPARGIMKPDIVFFGEGLDEFHEA
ANDKDVCDLLIVMGSSLKVRPVAMIPSSIPT-NVPQILINREPLKH-LTFDIELLGDCDVIIGEICQRLETDWV-----
>tr|L7LWW2|L7LWW2_9ACAR Uncharacterized protein OS=Rhipicephalus pulchellus PE=2 SV=1
---------------PRRTKLAHVNTL---DDVVHLLRNCQRVLVLTGAGVSVSCGIPDFRSRNGIYARPDPQAMFDIHYFRKDPRPFFKFAK---EIY-
PGQFTPSASHRFIKLLEDN-NKLLRNYTQNIDTLEQTCGIHNVITCHGSFATASCTRCHHKVDCNEEIFRIPLCPKCSLMAVMKPDIVFFGEGLQEFHQA
SHDKTQCDLLIVMGSSLKVRPVALIPSSIPP-EVPQILINRESLKH-VTFDVELLGDCDVIIKELCNRLGWDVA-----
>tr|J9K5K3|J9K5K3_ACYPI Uncharacterized protein OS=Acyrthosiphon pisum PE=4 SV=2
---------------PIRNRLRSVSSL---DDVVRLLKTSNRIMVLTGAGVSVSCGIPDFRSHNGVYARPDPQSMFCIDYFSKDPRPFFKFAR---EIY-
PGQFKPSPSHQFIKVLEKK-GRLLRNYTQNIDTLEQVVGINNVIECHGSFATASCTQCGHKVSAEPDVFRIPRCPICVNTGIMKPDIVFFGEGLDSFHKA
EDDKNNCDLLIVIGSSLKVRPVARIPNMLDK-HVPQILINRERLPH-MNFDVELLGDSDVIVDHLCRMLGSDWT-----
>tr|A0A0A1TAB2|A0A0A1TAB2_9HYPO Putative Sir2 family protein OS=Torrubiella hemipterigena GN=VHEMI07398 PE=4 SV=1
--------------LAKRAKLMQYNTV---DDAVDLIAKSKNIMVVTGAGISTSLGIPDFRSKGGLYSRSDPQEVFDISMFREDPSI---FYSIAKDILP
-ATTRFTPTHKFISMLHDR-GKLLTNYSQNIDNLEIAAGIDKLVQCHGSFGTASCIDCKYQVPGETDIGVIPKCPRCAADGLMKPDITFFGEELPEFRRL
THDRDKVDLVIIIGTSLKVTPVSEIVNFLPP-EIPQLYISREAIT-HTRFDINLLGDCDVVVAELCSRLGWPLVHDMV-
>tr|W9Q667|W9Q667_FUSOX NAD-dependent histone deacetylase SIR2 OS=Fusarium oxysporum f. sp. pisi HDV247 GN=FOVG_04456 PE=4 SV=1
--------------LSKRAKLLRHNTV---DDAVDLITKSNNIILITGAGISTSLGIPDFRSKGGLYSKSDPQEVFDIGVFRQDPTI---FYSVAKDILP
-STDRYTPTHKFIAMLHEK-GKLLTNYSQNIDNLEVKAGVDKLIQCHGSFGTATCVQCGYKCPGEAEIDKIPRCPRCIQAGVMKPDITFFGEALPEFRRL
THDRDKVDLVIVIGTSLKVTPVSEIVSWLPA-HIPQIYVSRQAVN-HINFDIDLLGDCDVVVSELCRRLRWPMVHDMV-
>tr|A0A0J5PEV8|A0A0J5PEV8_ASPFM Histone deacetylase SIR2 OS=Aspergillus fumigatus Z5 GN=Y699_06565 PE=4 SV=1
--------------FSRRPKLPQYNTI---DDAVRLLKESKNIIVLTGAGISTSLGIPDFRSKDGLYSQSDPQEVFDIHVFREDPNI---FFSIAKDILP
-TEKKFSPTHAFIKLLQDQ-GKLLTNYTQNIDNIEANAGIEKILQCHGSFATATCVKCHHKVKGEEDIGIVPECVACKEPGVMKPDITFFGEDLPEFRRL
LHDRDKVDLVIVIGTSLKVAPVAEVPGVLPR-NVPQIYISRTPVT-HTCFDIDLLGDCDVVVSELSRRAGWELNHDMI-
>tr|A0A0D9MQE5|A0A0D9MQE5_ASPFL Sir2 family protein OS=Aspergillus flavus AF70 GN=P034_00102103 PE=4 SV=1
--------------FSRRQKLPQYNTI---DDAVKLLQESKNIIVLTGAGISTSLGIPDFRSKDGLYSQSDPQEVFDIQIFREDPGI---FYSIAKDILP
-TEKKYSPTHGFIRLLQDK-GKLLTNYTQNIDNIEANAGIEKIVQCHGSFATATCVKCQYKVSGDADIGNVPECTSCQKPGVMKPDITFFGEDLPEFQRL
IHDRDKVDLVIVIGTSLKVAPVAEVPGVLPR-HVPQIYISRTPVS-HTGFDIDLLGDCDVVVSELCRRAGWDFKHEMI-
>tr|A0A0F7VIH3|A0A0F7VIH3_9EURO Putative Sirtuin 5 OS=Penicillium brasilianum GN=PMG11_04804 PE=4 SV=1
--------------FARRPKLPQHNTI---EDAVRLLQESKNIVVLTGAGISTSLGIPDFRSKDGLYSKSDPQEVFDIHVFREDPSI---FFSIAKDILP
-TEKKFSPTHGFIKLLQDK-GKLLTNYTQNIDNIEANAGVEKLVQCHGSFATATCVKCGFKVLGDADISKIPECTACHEPGVMKPDITFFGEDLPEFQRL
IHDRELVDLVIVIGTSLKVAPVAEVPGILPR-HVPQIYISRTPVS-HTGFDIDLLGDCDVVVSELCRRAGWNLQHHMI-
>tr|A2Q9C4|A2Q9C4_ASPNC Aspergillus niger contig An01c0250, genomic contig OS=Aspergillus niger (strain CBS 513.88 / FGSC A1513) GN=An01g07390 PE=4 SV=
--------------FSRRPKLPQYNTI---DDAVKLLKESKNIVVLTGAGISTSLGIPDFRSKDGLYSQSDPQEVFDIQVFREDPSI---FFSIAKDILP
-TEKKFSPTHAFIRVLQDK-GKLLTNYTQNIDNIEANAGVENIVQCHGSFATATCVKCQYKVKGDEEIGVIPQCDSCRKPGVMKPDITFFGEDLPEFRRL
LHDRDQVDLVIVIGTSLKVAPVAEVPGVLPR-TIPQLYISRTPVS-HTEFDIDLLGDCDVVVSELCRRAGWELKHEMI-
>tr|B8LWF6|B8LWF6_TALSN Histone deacetylase SIR2, putative OS=Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006) GN=TSTA_076
--------------FAKRQKLNEYNSI---EDAVNLLKKSKNVIVITGAGISTSLGIPDFRSKDGLYSRNDPQEVFDISLFHEDPSI---FFSVAKDILP
-TEKHFSPTHAFIKLLQDK-GKLLTNYTQNIDNIEANAGVEKIVQCHGSFATATCTKCGFKVPGDATIGKIPLCKRCKEPGVMKPDITFFGEDLPEFRRL
VEDREVADLVIVIGTSMKVAPVADVPSIIPS-TVPQIYISRTPVS-HIGFDIDLLGDCDVVVAELCRRAGWELEHSMI-
>tr|A0A0B2X0B1|A0A0B2X0B1_9HYPO NAD-dependent histone deacetylase, silent information regulator Sir2 OS=Metarhizium album ARSEF 1941 GN=MAM_02820 PE=4 SV=1
--------------LSKRIKLTDYNTV---DDAVDLVQKSKNIIVITGAGISTSLGIPDFRSEGGLYAKNDPQEVFNIDIFKDDPSI---FYSIAKDIIP
-ATDRYTPTHKFITMLHQR-GKLLTNYSQNIDNLEVKAGVDKLIQCHGSFGTATCIQCGYKTHGDADIGKIPRCPRCLQAGVMKPDITFFGEKLPEFKRL
THDRDKVDLVIVIGTSLKVTPVSEVSNWLSP-NVPQIYVSRQAVN-HINFDIDLLGDCDVVVTELCRRLGWPLRHEMV-
>tr|A0A0J6F3W4|A0A0J6F3W4_COCPO NAD-dependent histone deacetylase SIR2 OS=Coccidioides posadasii RMSCC 3488 GN=CPAG_01190 PE=4 SV=1
--------------YSKRLKLPQYNTI---DDAVELLKRSKNIIVLTGAGISTSLGIPDFRSKDGLYAKNDPQEVFDIGLFLEDPTI---FYSVAKDILP
-TEKRFSPTHAFIKLLQEK-GKLLTNFTQNIDNVEANAGISKLIQCHGSFATATCIQCKTQVPGEAETGLVPQCQECLKPGIMKPDITFFGEDLPAFDRL
IHDREIADLVIVIGTSLKVAPVSEVPGIMPR-DVPQLFISRTPVT-HIDFDIDMLGDSDVVVAELCRRAGWDLQHEMI-
>tr|T5BQ34|T5BQ34_AJEDE NAD-dependent histone deacetylase SIR2 OS=Blastomyces dermatitidis ATCC 26199 GN=BDFG_05662 PE=4 SV=1
--------------YSRRVKLSQYNTI---DDAVELLKKSKNIIVLTGAGISTSLGIPDFRSKDGLYSKTDPQEVFDIRLFHEDPNI---FYSIAKDILP
-TEKKFSPTHAFIRLLQDK-GKLLTNFTQNIDNLEANAGIENLIQCHGSFATASCVKCKYQVPGEQHVGALPECTACKKPGVMKPDITFFGEDLPAFKRL
IHDRDLADLVIVIGTSLKVAPVAEVPGILPR-HVPQIFISRDPVS-HIDFDINMLGECDVVVSELCRRAGWDLQHEMI-
>tr|A0A017S788|A0A017S788_9EURO Chromatin regulatory protein Sir2 OS=Aspergillus ruber CBS 135680 GN=EURHEDRAFT_461669 PE=4 SV=1
--------------FSRRQKLPQYNTI---DDAVKLLKGSKNIIVLTGAGISTSLGIPDFRSKDGLYSQSDPQEVFDIHIFREDPRI---FFSVAKDILP
-TENKFSPTHGFIRLLQDK-DKLLTNYTQNIDNIEANAGVDKIVQCHGSFATATCFKCQHKVSGDTDIGIIPECLECKKPGIMKPDITFFGEDLPEFRRL
VHDRERADLVIVIGTSLKVAPVAEVPGVLPR-NVPQIYISRTPIS-HTGFDIDLLGDCDVVVSELCRRAGWDLKHEMI-
>tr|V5GBH6|V5GBH6_BYSSN Histone deacetylase SIR2 OS=Byssochlamys spectabilis (strain No. 5 / NBRC 109023) GN=PVAR5_8086 PE=4 SV=1
--------------FSKRQKLSQYNTI---EDAVELLKKSNNIIVITGAGISTSLGIPDFRSKDGLYARNDPQEVFDINLFREDPSI---FFSVAKDILP
-TEKKFSPTHAFIRLLQDQ-GKLLTNYTQNIDNIEANAGVEKIVQCHGSFATATCVKCGHKVPGEAEIGNIPECTACKEPGVMKPDITFFGEDLPEFRRL
IHDRDKADLVIVIGTSLKVAPVAEVPGILPR-DVPQLYISRTPVS-HIGFDIDMLGDCDVVVSELCRRAGWNLKHEMI-
>tr|K1W5M3|K1W5M3_MARBU Sir2 family protein OS=Marssonina brunnea f. sp. multigermtubi (strain MB_m1) GN=MBM_09679 PE=4 SV=1
--------------LSKRIKLPHYNSI---DDAVNLIKTARNIIVLTGAGISTSLGIPDFRSKDGLYSKNDPQEVFDIRIFREDPTI---FYSVAKDIIP
-STDRFTPTHAFISLLQQK-GKLLTNYSQNIDNIETTAGIEKLIQCHGSFATASCIECGYQVDGHLDIGRIPHCDRCINSGIMKPDITFFGEALPRFDRL
THDKDLVDLVIVIGTSLKVAPVSEVVPYLPA-HIPQMYISRTPVS-HVNFDVDMLGDCDVVVAELCRRAGWDLEHEMI-
>tr|A0A0C3HIF5|A0A0C3HIF5_9PEZI Uncharacterized protein OS=Oidiodendron maius Zn GN=OIDMADRAFT_41286 PE=4 SV=1
--------------LSKRIKLPQYNTI---DDAVALIQKSTNIVVLTGAGISTSLGIPDFRSKDGLYSKNDPQEVFDIEVFKEDPTI---FFSIARDILP
-STDRFTPTHAFIYLLQQK-GKLLTNYSQNIDNIESVAGIEKLIQCHGSFATASCVECKYQVPGESDIGLIPRCDRCIAAGVMKPDITFFGEPLPKFDRL
THDKNLVDLVIVIGTSLKVAPVSEVVPYLPP-HIPQMYISRTPVS-HVNFDIDMLGDCDVVVAELCRRAGWELSHEMI-
>tr|A0A061HMX5|A0A061HMX5_BLUGR NAD(+)-dependent histone deacetylase OS=Blumeria graminis f. sp. tritici 96224 GN=BGT96224_4427 PE=4 SV=1
--------------LSKRIKLPQYNTV---DDAVNLIINAQNIIVLTGAGISTSLGIPDFRSKDGLYSKKDPQEVFDINVFREDPSI---FYSIAGDILP
-ATDRFTPTHAFIHLLQEK-GKLLTNYSQNIDNIESIAGIDKLIQCHGSFATASCVKCKYQVPGEADIGRIPRCENCTDAGVMKPDITFFGEPLPRFDRL
THDKNLVDLVIVIGTSLKVAPVSEVVPYLPA-RIPQMYISRTPVS-HVNFDMDLLGDCDVVVTELCRRAGWDLRHEMV-
>tr|A0A0B1NXI8|A0A0B1NXI8_UNCNE Putative nad-dependent histone deacetylase sir2 OS=Uncinula necator GN=EV44_g6388 PE=4 SV=1
--------------LSKRIKLQQYNTI---DDVVALLQKSKNIVVLTGAGISTSLGIPDFRSKDGLYSKNDPQEVFDINIFKEDPSI---FYSIAGDILP
-ETNRFTPTHAFIYLLQQK-GKLLTNYSQNIDNIETVAGIEKLIQCHGSFATASCVDCKYQVPGDTDIGRIPLCENCTQAGVMKPDITFFGEALPRFARL
THDRHLVDLVIVIGTSLKVAPVSEVVPYLPA-QIPQIFISRTPVS-HVNFDVDLLGDCDIVVAELCKRAGWDLNHEMV-
>tr|A0A0B7K6T1|A0A0B7K6T1_BIOOC Uncharacterized protein OS=Bionectria ochroleuca GN=BN869_000006738_1 PE=4 SV=1
--------------LSKRAKLNRFNTV---NDAVDLIEKSNNIILLTGAGISTSLGIPDFRSKGGLYSKNDPQEVFDIDVFKSDPTI---FYQVAKDIIP
-STERYTPTHKFIAMLHER-GKLLTNYSQNIDNLEIKAGVDKLIQCHGSFGTATCIKCGYKVNGESDIGIIPRCTRCVQAGVMKPDITFFGESLPEFRRL
THDRDKVDLVIVIGTSLKVTPVSEIVSWLPS-HIPQIYISRQAVN-HINFDIDLLGDCDIVVTELCKQLHWPFKHEMV-
>tr|U4LQ96|U4LQ96_PYROM Similar to NAD-dependent protein deacetylase hst1 acc. no. C8V3W5 OS=Pyronema omphalodes (strain CBS 100304) GN=PCON_02630 PE=4
--------------MIQRTRIPHVNSV---EHVVDLLRKSKNIIVLTGAGISTSLGIPDFRSKGGLYSRNDPQEVFDINIFNDDPTI---FYSVAKDILP
-ETKQFSPTHAFIALLQSK-NKLLTQYTQNIDNLEHLAGIEKLIQCHGSFATASCTKCGHKVPGETEICQIAKCDNCLRAGVMKPDITFFGEQLPTFKRL
VQDRMKADLLVCIGTSLKVAPVSEIIGFLPE-NVPQIYISKTPVN-HIEFDVELLGPCDEVVAELCRLAGWTLTHEML-
>tr|D4AW63|D4AW63_ARTBC Uncharacterized protein OS=Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) GN=ARB_00428 PE=4 SV=1
--------------SSKRLKLPDYNTI---DDVVQLMQKAKNIIVITGAGISTSLGIPDFRSKDGLYSKSDPQEVFDIEVFREDPSI---FYSIAKDILP
-TEKRYSPTHAFIRLLQDK-GKLLTNFTQNIDNIEGAAGIEKMIQCHGSFATASCMDCKHQVPGEQTIGEIPKCARCEEAGVMKPDITFFGEELPIFKRL
LHDRELTDLVIVIGTSLKVAPVAEVPGIIPC-DVPQVHISRTPVS-HIEFDVDMLGDCDVVVSELCRRAGWDLQHDMI-
>tr|A0A086T965|A0A086T965_ACRCH NAD-dependent protein deacetylase-like protein OS=Acremonium chrysogenum ATCC 11550 GN=ACRE_032480 PE=4 SV=1
--------------LSRRAKLSRYNTV---DDAVDLIRRSSNIIILTGAGISTSLGIPDFRSKGGLYSKSDPQEAFDIDVFKQDPTI---FYSVAKDIVP
-AIDRYTPTHKFIAMLHEH-GKLLTNYSQNIDNLEVMAGVDKLIQCHGSFGTASCIQCGYRIQGEKDIGRIPECPRCVQAGIMKPDIIFFGEPLPEFKRL
THDRDKVDLVIVIGTSLKVTPVSEIVSWLPS-HIPQIYVSRQAVN-HINFDIDLLGDCDVVITELCRRLGWDLNHEMV-
>tr|A0A094KH78|A0A094KH78_9PEZI Uncharacterized protein OS=Pseudogymnoascus pannorum VKM F-4520 (FW-2644) GN=V502_02955 PE=4 SV=1
--------------LSKRSKLSSYNTI---DDVVKLLDKCKNIIVLTGAGISTSLGIPDFRSKDGLYAKSDPQEVFDINLFKEDPSI---FYSVARDILP
-TTSRFTPTHAFIKLLQDK-NKLLTNYSQNIDNIEGVAGVEKLIQCHGSFATASCTKCGAQVAGEADIGLIPRCKRCVQAGVMKPDITFFGEALPTFDRL
THDKDIVDLVIVIGTSLKVAPVSEVVPFLPA-HIPQIYISREPVK-HVNFDVDMLGDCDVVVAELCRRAGWELEHEMI-
>tr|A0A0A2JBL4|A0A0A2JBL4_PENEN Sirtuin family OS=Penicillium expansum GN=PEX1_055520 PE=4 SV=1
--------------FSRRPKLPQYNSI---DDAVRLLRESRNIIVLTGAGISTSLGIPDFRSKDGLYSKSDPQEVFDIHVFREDPNI---FFSIAKDILP
-TEKKWSPTHAFIRLLQDK-GKLLTNYTQNIDNIEANAGVEKIVQCHGSFATATCVKCGFNVPGDAEIGNVPRCTACKEPGVMKPDITFFGEDLPEFERL
IQDRELADLVIVIGTSLKVAPVAEVPGILPR-NVPQIYISRTPVS-HTEFDIDLLGDCDVVVSELSRRAGWDLQHHMI-
>tr|R4X7D0|R4X7D0_TAPDE Chromatin regulatory protein sir2 OS=Taphrina deformans (strain PYCC 5710 / ATCC 11124 / CBS 356.35 / IMI 108563 / JCM 9778 / N
--------------YSKRERLPDVKTV---EDVATLLQSCKNIIVITGAGISTSLGIPDFRSEGGIYSRTDPQELFDIHLFRESPYM---FYNFAKELIP
-VERGYSPTHAFIRLLQDQ-GRLLRQYTQNIDNIESTVGIDRLVQCHGSFKSATCLTCHKVVPGETDIGNVPRCADCIRYALMKPDITFFGEQLSDFTQI
MKDKDEADLVLCIGTSLRVQPVADIPRLIPK-HIPQIFISREKAGREYVFDVELLGTCDSYVSHLVKQLGLTQEFELL-
>tr|A0A084GGM4|A0A084GGM4_9PEZI Histone deacetylase OS=Scedosporium apiospermum GN=SAPIO_CDS0826 PE=4 SV=1
--------------LNKRAKLPHLNTV---QDAADLISRSKNIICLTGAGISTSLGIPDFRSKGGLYSKNDPQEVFDIEQFRADPSI---FYSVAKDILP
-STDRFTPTHAFIAMLQQR-GKLLTNYSQNIDNLEAKAGISKLVQCHGSFATASCIECGFKTDGESDIGTLPRCPECAKAGVMKPDIIFFGEALPDFLRL
THDRDVVDLVVVIGTSLKVSPVSEIVSYLPS-HVPQIYISRTPVE-HLNFDIDLLGDCDVVVVELCRRMGWELEHEMI-
>tr|A0A0G4LGA6|A0A0G4LGA6_9PEZI Uncharacterized protein OS=Verticillium longisporum GN=BN1708_003402 PE=4 SV=1
--------------LAKRAKLPSHNSL---DDAVALLTRSRNIMVITGAGISTSLGIPDFRSKKGLYAQHDPQEVFDINVFRDDPTI---FYTVAKDIIV
-NTDRYSPTHAFIAMLDRM-GKLLTNYTQNIDNVEARAGIDRIIQCHGSFATASCLECGYNCPGEDAIKQIPRCPKCVAGGVMKPDITFFGEGLPAFRRL
AHDRDRVDLVLVIGTSLKVTPVSEIVSWLPP-HVPQLCISLDPIN-HINFDIDLLGHCDVVVAELCRRAGWDLRHDMV-
>tr|J5JP00|J5JP00_BEAB2 Sir2 family protein OS=Beauveria bassiana (strain ARSEF 2860) GN=BBA_06260 PE=4 SV=1
--------------LSKRAKIARYNSV---DDAVDLIAKSSNIVLITGAGISTSLGIPDFRSKGGLYSKSDPQEVFDIDVFKEDPSI---FYSVAKDIIP
-ATERYTPTHKFIAMLHQR-GKLLTNYSQNIDNLEIKAGVDKLIQCHGSFGTASCVQCGHRIAGEFDIGIIPRCPKCTQAGVMKPDITFFGEALPEFRRL
TNDRDKVDLVIVIGTSLKVTPVSEIVSWLPS-HIPQIYVSRQPVN-HINFDIDLLGDCDVVVAELCRRLGWPLRHEMV-
>tr|A0A0M8N8Q3|A0A0M8N8Q3_9HYPO NAD-dependent protein deacetylase hst1 OS=Escovopsis weberi GN=ESCO_003826 PE=4 SV=1
--------------LEKRAKLPQHNTV---DDAVRLIQRSSNIIVITGAGISTSLGIPDFRSKDGLYAKSDPQEVFDIALFREDPAI---FYSVARDIIP
-STSRFTPTHRFLAMLHER-GKLLTNYSQNIDNLEVKAGLDKLIHCHGSFGTATCMRCGFHAPGESDIGKIPRCTKCIDVGVMKPDIVFFGENLPEFKRL
TNDRDKVDLVIVIGTSLKVTPVSEIVSWLPP-HIPQIYLSRQAVS-HINFDIDLLGDCDVIVAELCRRLGWDLVHEMV-
>tr|J3NH76|J3NH76_GAGT3 NAD-dependent histone deacetylase SIR2 OS=Gaeumannomyces graminis var. tritici (strain R3-111a-1) GN=GGTG_00614 PE=4 SV=1
--------------LQKRAKLFQYNTV---DDAVSLLKRSKNIVVLTGAGISTSLGIPDFRSKDGLYSMDDPQQVFELSLFHEDPSI---FYSVARKVLP
-NHNRCSPTHAFIALLQQK-GKLLTNYTQNIDNIEEVAGIERLVQCHGSWSTATCTRCGHRVPGKTTVGGIPRCLKCAPGGVMKPDITFFGEQLPRFERL
FHDRDLVDLVIVIGTSLKVKPVSELVPVLPA-HVPQIYISRDAVS-HAHFDIDLLGDCDVVVAELCRRAGWDLNHEMV-
>tr|G4MS03|G4MS03_MAGO7 NAD-dependent histone deacetylase SIR2 OS=Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) GN=MGG_02488 PE=4 SV=1
--------------LQKRAKLEQYNSF---DDAVNLIKRSKNIIVLTGAGISTSLGIPDFRSKNGLYSMDDPQQVFDLGLFHEDPSI---FYSIARKVLP
-NHERCSPTHAFIAMLQEK-GKLLTNYTQNIDNIEETAGIERLVQCHGSWSSATCIRCGHKVPGKTVVGGIPRCEKCGVEGIMKPDITFFGEALPRFERL
LHDRDLVDLVIVIGTSLKVKPVSELVPVLPA-NVPQIYISRDPVS-HVHFDIDLLGDCDVVVAELCRRAGWDLDHEMI-
>tr|A0A0F4ZF68|A0A0F4ZF68_9PEZI Uncharacterized protein OS=Thielaviopsis punctulata GN=TD95_000961 PE=4 SV=1
--------------MSHRPKLMNVNTV---QDAVNLIRKSSNIVVVTGAGISTSLGIPDFRSKGGLYSQSDPTDVFDIEIFREDPSL---FYSVAKDILP
-STHRYTPTHGFIAELDRR-NKLLTNYTQNIDNLESFAGIDRLIQCHGSFKTATCFTCGLRVPGDAHIGRIPPCPRCTALRIMKPDITFFGEQLPAFDRL
EHDRALADLVIVIGTSLKVKPVSEISSFLPA-DVPQIYISRDPIG-HINFDIVLLGECDVIVAELARRLHWDFTHEMI-
>tr|A0A0F8AZR3|A0A0F8AZR3_CERFI NAD-dependent protein deacetylase hst1 OS=Ceratocystis fimbriata f. sp. platani GN=CFO_g3623 PE=4 SV=1
--------------LARRVRLDAYRSL---DDVVGLIERANNIIVVTGAGISTSLGIPDFRSKDGLYSQYDPTDVFDIDVFREDPSL---FYSVAKDILP
-STKRFTPTHAFIADLDRR-GKLLTNYTQNIDNIESAAGIDRLVQCHGSFKTATCFTCGFRVDGELEIGNIPACSRCAALAVMKPDITFFGEALPAFDRL
THDRDKVDLLIVIGTSLKVRPVSEISAVLPP-DVPQIYINRDPIG-HVTFDILLLGDCDVVVAELAKRLKWDFKHEMI-
>tr|G0SAN3|G0SAN3_CHATD NAD-dependent histone deacetylase-like protein OS=Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719) GN=CTHT_0
--------------LSKRAKLTKYNTV---DDAVALLHKCNNIIVLTGAGISTSLGIPDFRSKGGLYSKNDPQEVFDITVFRQDPSI---FYSVARDILP
-NHDRFTPTHAFIKLLQDK-GKLLTNYSQNIDNLEAKAGIDKLVQCHGSFATATCTKCGRKVPGESQIGDIPRCTAT--NGVMKPDITFFGEPLPEFRRL
THDRDRVDLVIVIGTSLKVAPVSEVVPYLPP-HIPQIYISRTPVS-HVNFDIDLLGDCDVVVAELCRRAGWELKHEMI-
>tr|Q2GSR2|Q2GSR2_CHAGB Putative uncharacterized protein OS=Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970) GN=C
--------------LSKRAKLPKYNSV---DDAVDLLKKSKNIVVLTGAGISTSLGIPDFRSKGGLYSKSDPQEVFDITVFRQDPTI---FYSVARDILP
-SHDRFSPTHAFIALLQNK-GKLLTNYSQNIDNLEAKAGIEKLVQCHGSFATASCVKCGHRVPGESEIGDIPRCRKCAQCGVMKPDITFFGEPLPEFRRL
THDRDLVDLVIVIGTSLKVAPVSEVVPFLPA-HVPQLYISRTPVS-HVNFDIDLLGDCDVVVAELCRRAGWDLDHEMV-
>tr|M1VU84|M1VU84_CLAP2 Related to NAD-dependent histone deacetylase OS=Claviceps purpurea (strain 20.1) GN=CPUR_00801 PE=4 SV=1
--------------LSKREKLSAYNTV---DDAVRLLTQCSNIIVITGAGISTSLGIPDFRSKGGLYSKGDPQEVFDINVFRQDPSI---FYSIAKDIIP
-ATGRYTPTHQFIAMLHQR-GKLLTNYSQNIDNLEVKAGLSKLIQCHGSFGTATCVQCRYQTNGEAEIGHIPRCPRCIQAGVMKPDITFFGEALPEFERL
THDRDKVDLVIVIGTSLKVSPVSEIVSFVPQ-HVPQIYVSREPVT-HVEFDIDLLGDCDVVVAELCRRLGWPMVHDML-
>tr|A0A063C9U7|A0A063C9U7_9HYPO Putative histone deacetylase SIR2 OS=Ustilaginoidea virens GN=UV8b_881 PE=4 SV=1
--------------LSKRVKLGSYNTV---DDAVRLIAKCGNIVVITGAGISTSLGIPDFRSKGGLYSKGDPQEVFDIDVFKQDPTI---FYSVARDIIP
-ATDRYTPTHKFIAMLHQR-GKLLTNYSQNIDNLEVKAGLHKLVQCHGSFGTASCVRCGHQVQGDIDIGNIPRCPRCVRAGVMKPDITFFGEALPEFQRL
THDRDKVDLVIVIGTSLKVRPVSEIVSWLPS-SVPQIYVSREPVT-HINFDIDLVGDCDVVVTELCRRLGWPLVHEMV-
>tr|Q07FY7|Q07FY7_XENTR Sirtuin (Silent mating type information regulation 2 homolog) 3 (S. cerevisiae) OS=Xenopus tropicalis GN=sirt3.2 PE=2 SV=1
-------------------------------------NCCTNIIVMAGAGISTASGIPDFRTPSGLYDNPYPEAIFDINYFVCNPNP---FFHLAKELF-
PGKYKPNLVHYFIKLLHDK-GLLLRCYTQNIDGLERLAGIEKIVEVHGTFFSASCSLCYTPFPANEAIGNPPCCKFCA--GPVKPDIVFFGEDLQTFTQA
YQDFPKADLLIIMGTSLKIEPFASLVNTVKP-SIPRLLINREKVGFARRRDVAELGDLCDIIHTMVSRL----------
>tr|A0A0L8FVJ2|A0A0L8FVJ2_OCTBM Uncharacterized protein OS=Octopus bimaculoides GN=OCBIM_22006692mg PE=4 SV=1
-------------------------------------NDISKIVVLVGAGLSTNSGIMDFRTPTGLYDNPYPEAIFDIDYFKYNPKP---FFALAKELY-
PSKYRPNYNHYFLRLLHDK-GLLLRLYTQNIDGLERLSGIAKLIECHGTFAHATCLSCRKKYKGNEVIEDVAKCKHCK--GIVKPDIVFFGEDLKSFFQY
HKDMSRAELVLIMGTSLEVHPFAGIIDYVPS-TVPRILFNMKAVGFRRANDFTVAGDLTESLEKLVTQL----------
>tr|B3RLQ5|B3RLQ5_TRIAD Putative uncharacterized protein OS=Trichoplax adhaerens GN=TRIADDRAFT_52084 PE=4 SV=1
-------------------------------------KSCKNILILAGAGISTSSGIPDFRSPTGIYSISSPTDAFDIDYFRSNPAV---FYELAKDLY-
PGQYRPNYAHYFIKLLCDK-GLLGRMYTQNIDGLERLADISKLVEAHGTFSSATCTCCKKTFNGDFIIKIIPKCDRCS--GIIKPDIVFFGENLKRFYKL
YKDIAGCDLVIVMGTSLQVEPFASLVDKIPQ-RTPRVLINKEIVGFTRFTDIIYTGDIVDGLKELAKNA----------
>tr|A0A0C2YIH9|A0A0C2YIH9_HEBCY Uncharacterized protein OS=Hebeloma cylindrosporum h7 GN=M413DRAFT_445656 PE=4 SV=1
----------------------------------ISSKDCQRIVLMVSVGISTSAGIPDFRSPTGMLNLPHPEAVFEIGFFSKNPVP---FYTLAHELY-
PGKFRPTIAHSFIRLLDEK-SLLHMCFTQNIDTLERRAGVHKIIEAHGSFATQKCINCKQPYDGDKHIKKIARCESCR--GYVKPDIVFFGEGLPRFINS
MSNLQEADLLIVMGTSLTVQPFASLAEMVDD-SCPRVLINLDHVGDGRSDDVVLLGKCDDIVTKLCNELG---------
>tr|K9HFV4|K9HFV4_AGABB Uncharacterized protein OS=Agaricus bisporus var. bisporus (strain H97 / ATCC MYA-4626 / FGSC 10389) GN=AGABI2DRAFT_224508 PE=4
----------------------------------IKSNKCKNIVLMLGAGVSTSAGIPDFRSPTGLLKLPYPEAVFEIEYFRRNPVP---FYTLAQELY-
PGKFRPTIAHSFIRLLHDK-GLLLKCFTQNIDTLERRAGVEKIIEAHGSFAAQRCIDCEAPYDDFLHIKTIPRCDGCR--GLVKPDIVFFGESLPDFIES
IPLLQQADLLIVMGTSLTVHPFAMLAGLVET-KCPRVLINLEEVGDSRTDDVLLLGRCDEMVRELCQELG---------
>tr|A0A0C9XKZ1|A0A0C9XKZ1_9AGAR Unplaced genomic scaffold K443scaffold_174, whole genome shotgun sequence OS=Laccaria amethystina LaAM-08-1 GN=K443DRAFT_681985
----------------------------------IKSDGCTNIVLMLGAGVSTSAGIPDFRSPTGLLNLPHPEAVFEISFFRRNPVP---FYTLAHELY-
PGKFRPTIAHSFIRLLAEH-SLLFQCFTQNIDTLERRAGVKKIIEAHGSFATQRCIDCGEPFDDEMHIKKIATCEECG--GLVKPDIVFFGESLPNFIRA
IPLMREADLLIVMGTSLTVQPFASLAQRVDD-SCPRVLINLDRVGDGRSDDVVLLGKCDDIVRDLCKELG---------
>tr|A0A0D2NWU3|A0A0D2NWU3_9AGAR Uncharacterized protein OS=Hypholoma sublateritium FD-334 SS-4 GN=HYPSUDRAFT_40027 PE=4 SV=1
----------------------------------MKSKDCKNVMMMLGAGVSTSAGIPDFRSPTGLLNLPHPEAVFEINFFRRNPVP---FYTLAHELY-
PGKFRPTITHSFIRLLAEK-GLLHTCFTQNIDTLERRAGVEKIIEAHGSFATQRCIDCSETFDDNDHIKKIARCVSCG--GYVKPDIVFFGEALPIFIRA
VPNLRKADLLIVMGTSLTVQPFASLAERVDD-SCPRVLINLDHVGSGRSDDVALLGKCDEVVRDLCKELG---------
>tr|N9UZ15|N9UZ15_ENTHI NAD-dependent deacetylase sirtuin-3, mitochondrial, putative OS=Entamoeba histolytica HM-1:IMSS-A GN=EHI7A_190330 PE=4 SV=1
----------------------------------MKYRKPSNVVVMAGAGISTSAGIPDFRTPTGLYDNLFPTAVFDINYFKSNPKPFYTIASELMPGLG
--KYFPTPTHYFLTYLNKL-GYISMLFTQNIDGLEIQSGFEKLVMAHGNYYSGHCLKCKKSFKQSYFIRKVCYCDSCK--GLVKPDIVFFGEGLPQFFNN
FEKVEECDLLIVLGTSLLVQPFASLIDLTK-KNTPRVYINMKDFNSFKINDLQIIGKCDESILEIAEYMGIG-------
>tr|A0A0A1UGH7|A0A0A1UGH7_ENTIV NAD-dependent deacetylase sirtuin-2, putative OS=Entamoeba invadens IP1 GN=EIN_370090 PE=4 SV=1
----------------------------------MKAKHPKKIVVMAGAGMSTSAGIPDFRTPTGLYDNLYPTAVFDIDYFEENPQPFYTLAKELMPGIG
--KYFPTPTHHFVGFLNNL-KVLSMLFTQNIDGLETVANIDKTVFAHGHYNTGHCLKCKKLVQKDEFIMKVSKC-KCG--GVIKPDIVFFGENLPRFFDS
FKYVKDCDLLICIGTSLVVEPFASLAEMPE-LGTPRVLINMEDVGDFYKDDLKLLGKCDDIIFDIVNEIGQK-------
>tr|C4LSH3|C4LSH3_ENTHI Sir2 family transcriptional regulator, putative OS=Entamoeba histolytica GN=EHI_151300 PE=4 SV=1
----------------------------------IRKNHVKNIIALVGAGMSTTAGIPDFRSPTGLYFNLYPEAVFDMNYFPSNPAPFYEVMKVMFPGQG
--TYFPTKCHRFLKLLNDK-GILKMVYTQNIDGLESVAGIDKVICSHGTFRSSHCLSCHKKYPTSVFIKEIIHC-NCG--GLIKPDIVFFNESLPEFFES
IKKFDDCDMLLIIGTALVVYPFANLVDHVP-INCPRVCINREKVGKMLGRDVALLGGCDDIASELAKYLEWE-------
>tr|A0A0A1U0N8|A0A0A1U0N8_ENTIV NAD-dependent deacetylase sirtuin-2, putative OS=Entamoeba invadens IP1 GN=EIN_097040 PE=4 SV=1
----------------------------------IVSHNVRNIIALVGAGMSTSAGIPDFRSPTGLYFNLYPEAVFDMEYFPTNPAPFYEVMKDMYPGLG
--KYFPTKCHRFLKMLNDM-GRLKMIFTQNIDGLEKEAGIEKVVYSHGTFRTARCLKCGMKFDTNVFITEIIRC-QCG--GLIKPDIVFFNESLPAFFEN
VEQFDDCDMLFVIGTAMVVYPFALLMEQVS-VNCPRIVFNREEIGKSQGRDAGLMGNCDDIAEEMCKAVGWK-------
>tr|A0A0R3TMG4|A0A0R3TMG4_HYMNN Uncharacterized protein OS=Hymenolepis nana PE=4 SV=1
---------SLFAEKSSRKPLKQFHSL---EAAINLLKEKSKILVLTGAGISVSCGIPDFRSRNGVYARRNPQDMFDLKFFKSNPNPFYTFAKE---LF-
PGQFKPSYTHRFIRLLEKK-SKLLRNYTQNIDTLEEIAGISKIIHCHGSFATASCLTCHSQLPGEEAIQHVPFCPHCRPLGLMKPDIVFFSESLSEFYTL
EKDVKDVDLVLVMGSSLKVRPVSHIPNSLP-NHVPQILINREPLS-NHQFDVELLGECDVIVEYLCKQLGWDV------
>tr|A0A068Y3X5|A0A068Y3X5_ECHMU NAD dependent deacetylase sirtuin 1 OS=Echinococcus multilocularis GN=EmuJ_000698900 PE=4 SV=1
---------SLLSETNNRKRLKQYSTI---ESVVQLLRESSHILVLTGAGISVSCGIPDFRSQDGVYARHSPQDMFDLQYFLRNPNPFFNFAKE---LF-
PGQFKPSYAHRFIRLLERK-SKLLRNYTQNIDTLEQVAGIKKVIQCHGSFATASCVSCGYKVRGEEAIQRIPHCPHCRPHGVMKPDIVFFGEGLPEFESL
HQDLREVDLVLVMGSSLKVRPVSHIPDSVP-SKVPQILINRESLS-NHNFDTELLGDCDVILEHLCRQLEWSV------
>tr|A0A0R3WZJ1|A0A0R3WZJ1_HYDTA Uncharacterized protein OS=Hydatigena taeniaeformis PE=4 SV=1
---------SLLSETTSRKRLKQFSTL---ESVVQLLRDSSRILVLTGAGISVSCGIPDFRSRNGVYARRSPQDMFDLQFFLRDPNPFFTFAKE---LF-
PGHFKPSYAHRFIRLLERK-SKLLRNYTQNIDTLEQVAGIENIVQCHGKFATASCVSCSYKVRGEDAIQRIPHCPQCRPYGVMKPDIVFFGEGLPEFEYL
HQDLREVDLVVVMGSSLKVRPVSHIPDSVP-GKVPQILINRESLS-HHNFDTELLGDCDVILQYLCRQLGWNV------
>tr|A0A0R3UPJ2|A0A0R3UPJ2_9CEST Uncharacterized protein OS=Mesocestoides corti PE=4 SV=1
---------SVLSGQPHRRRLEQFATL---DSVVKLLRHRSRILVLTGAGIS-----------------------------------------E---LF-
PGQFKPSFAHRFIKLLERK-GKLLRNYTQNIDTLEQAAGITRVIQCHGSFATASCVTCQYQVPGEAAIQRVPRCPRCCPSGIMKPDIVFFGEGLPEFTSL
QEDVHHADLILVIGSSLKVEPVSHIPDSVV-PEVPQILINRESLT-SHNFDTELLGDCDVILEELCSRLGWNL------
>tr|N6TP08|N6TP08_DENPD Uncharacterized protein (Fragment) OS=Dendroctonus ponderosae GN=YQE_03809 PE=4 SV=1
-------------------KLRHVNTL---DDVVRLLK------VLTGAGVSVSCGIPDFRSRDGIYSRPNPQAMFDINYFSQDPRPFFKFAKD---IY-
PGKFKPSPCHRFIKLLEKH-NKLLRNYTQNIDTLEKEASIERVIECHGSFATATCTKCEHKVGADNIVQKIPMCEKCHGSGIMKPDIVFFGEGLDTFHDA
MSDKTEGDLLVVIGSSLKVRPVALIPNSLPA-HVPQILINREPLSH-CHFDVELLGDCDVIINHLCKMLGQNWEEG---
>tr|V3ZNN2|V3ZNN2_LOTGI Uncharacterized protein OS=Lottia gigantea GN=LOTGIDRAFT_108079 PE=4 SV=1
-------------------KLENINTF---EDVVHLLKTCKKIMVLTGAGVSVSCGIPDFRSRDGVYARPDPQAMFDIHFFKGDQRPFFKFAKE---IY-
PGQFEPSKCHKFIKLLDDH-NKLLRNYTQNIDTLEQVAGIKNVIQCHGSFATAQCMACKHKVDADKDIQVIPACPVCPPYAIMKPNIVFFGESLEEFHRQ
MDDKDECDLLIVIGSSLKVRPVALIPNSLPA-HVPQILINRERLRH-MDFDVELLGDCDVIVNELCKHLGEGWDKL---
>tr|A0A091GK20|A0A091GK20_9AVES NAD-dependent protein deacetylase sirtuin-1 (Fragment) OS=Cuculus canorus GN=N303_11370 PE=4 SV=1
-------------------KRKDINTI---DDAVKLLQECKKIMVLTGAGVSVSCGIPDFRSRDGIYARPDPQAMFDIEYFRKDPRPFFKFSKE---IY-
PGQFQPSLCHKFIALMDKE-GKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVDCEGDIQVVPRCPRCPPLAIMKPDIVFFGENLEQFHRA
MYDKNEVDLLIVIGSSLKVRPVALIPSSIPH-EVPQILINREPLPH-LHFDVELLGDCDVIINELCQRLGSEYTKL---
>tr|A6XDL2|A6XDL2_SCHMA Sirtuin 1 OS=Schistosoma mansoni GN=Sirt1 PE=2 SV=1
-------------------RLRRINSL---EKVLSLLSTCTSILVITGAGISVSCGIPDFRSRDGIYARSSPQAMFDMSYFKRNPIPFFKFAKE---LF-
PGQFSPSITHRMIALLESK-DKLLRNYTQNIDTLEQAAGITRLIQCHGSFASATCTNCKLKVSSDEAIQSIPRCTNCWPYGVLKPDIVFFGEGLNEFHDS
LNDIKQTDLVLVIGSSLKVRPVSHIPNAVPR-QVPQILINREPLSN-HDFDVELLGDCDVIVSELCHRLGWEVSGL---
>tr|F7FBX2|F7FBX2_MACMU Uncharacterized protein OS=Macaca mulatta GN=SIRT1 PE=4 SV=1
-----------------------------IEDAVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARPDPQAMFDIEYFRKDPRPFFKFAKE---IY-
PGQFQPSLCHKFIALSDKE-GKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVDCEAIPYNSP------IVKI--MKLASYCGNLLLFHTS
MKYKDEVDLLIVIGSSLKVRPVALIPSSIP-HEVPQILINREPLPH-LHFDVELLGDCDVIINELCHRLGGEYA-----
>tr|V9KET2|V9KET2_CALMI NAD-dependent deacetylase sirtuin-1 (Fragment) OS=Callorhinchus milii PE=2 SV=1
-----------------------------IEDVVKMLRESKKIMVLTGAGVSVSCGIPDFRSRDGIYARPDPHAMFDIEYFRKDPRPFFKFAKE---IY-
PGQFQPSLCHRFIALLDKQ-QRLLRNYTQNIDTLEQVTGIHRIVECHGSFAMASCLACKYKVDCEADVFVVPQCPRCPPLAIMKPDIVFFGENLPLFHRS
MKYKDEVDLLIVIGSSLKVRPVALIPSSIP-HDVPQVLINREPLSH-LNFDVELLGDCDVIINELCHRLSGEFE-----
>tr|A1L2V3|A1L2V3_XENLA LOC100036963 protein OS=Xenopus laevis GN=sirt1 PE=2 SV=1
-----------------------------IDDAVKLLQESKKIIVLTGAGVSVSCGIPDFRSRDGIYARPNPQAMFDIEYFRKDPRPFFKFAKE---IF-
PGQFQPSLCHRFIAMLDKE-GKLLRNYTQNIDTLEQVAGIEKIIQCHGSFAEASCLVCKYKVDCEADIFIVPRCPQCSPLAIMKPDIVFFGENLPQFHRA
MKYKNEVDLLIVIGSSLKVRPVALIPSSIP-HEVPQILINREPLPH-LHFDIELLGDCDVIINELCQRLDGKYS-----
>tr|H3AHF8|H3AHF8_LATCH Uncharacterized protein OS=Latimeria chalumnae GN=SIRT1 PE=4 SV=1
-----------------------------LEDVVRLLQECKKIVILTGAGVSVSCGIPDFRSRDGIYARPDPQAMFDIDYFRRDPRPFFKFAKE---IY-
PGQFQPSPCHKFIAMLDKE-GKLLRNYSQNIDTLEKVAGIQKIIECHGSFATASCLICKYMVDCEVDIFVRYRKSLFPLLFFPRTWALFFGNDLKIVCLE
LSYKESQNVFVCIGYSLQIHPSLLQSSSIP-HEVPQILINREPLPH-FNFDVELLGDCDVIINELCHRLGGEYK-----
>tr|A0A023FB47|A0A023FB47_TRIIF Putative nad-dependent histone deacetylases and class i sirtuins sir2 family OS=Triatoma infestans PE=2 SV=1
------------TEPPKRNRLAKTTSL---EDVIQLLQTCSKIIILTGAGVSVSCGIPDFRSKDGVYARPDPQAMFDINYFRQDPRPFFKFAKE---IY-
PGQFKPSPCHRFIKMLEKQ-KKLLRNYTQNIDTLEKVAEIENVVECHGSFATATCTRCGHRVTCDKDVQSIPFCTECGKRGIMKPDIVFFGEGPERFHDA
MAFKDKCDLLIVIGSSLKVRPVALIPSSLP-ADVPQVLINRERLPH-MNFDVELLGDSDVIVDHLCRILGGDWKE----
>tr|A0A0P5S1V9|A0A0P5S1V9_9CRUS NAD-dependent protein deacetylase sirtuin-1 OS=Daphnia magna PE=4 SV=1
------------SEPPRRERLRHINSI---SDAVRLLRSCKKILVLTGAGVSVSCGIPDFRSRDGIYARPDPQAMFDIHYFRKDPRPFFKFARD---LW-
PGQFTPSKCHKFIRLLERQ-NKLLRNYTQNIDTLEQQADIERVIQCHGSFATATCLRCQHRVPSNKDIQRIPLCPKCSNQPIMKPDIVFFGEGPDEFHQA
MVLKEECDLIIVIGSSLKVRPVALIPCALP-NHVPQILINREPLRH-MVFDVELLGDCDIIVNQLCHLLGPQWED----
>tr|T5A8E8|T5A8E8_OPHSC NAD-dependent histone deacetylase, silent information regulator Sir2 OS=Ophiocordyceps sinensis (strain Co18 / CGMCC 3.14243) G
-------------------------------------GRGKNIVVLTGAGISTAAGIPDFRSPTGLYNNLYAEAVFEIEFFRQHPEP---FYVLAKELY-
PGKFHPTVSHAFIALLARK-GLLLMLFTQNIDCLERIAGVDKIVEAHGSFATQRCIECKSEFPDDRMVGKVPHCADCG--GMVKPDIVFFGESLPAFSQK
LHMTAMADLVLIIGTSLTVYPFAELPDMAR-EGKPRVLFNMERVRRGRSDDVVELGPCDDGIRTLADAL----------
>tr|A0A084FW89|A0A084FW89_9PEZI Sir2 family protein OS=Scedosporium apiospermum GN=SAPIO_CDS10044 PE=4 SV=1
-------------------------------------GKAQQIVVLTGAGISTSAGIPDFRSPTGLYANLYPEAVFDIQFFRKNPLP---FYVLAKELY-
PGNFHPTLSHAFISLLATK-GLLHKLFTQNIDCLERAAGVDRIIEAHGSFATQRCIECKTPFPDELMVARVPKCVTCS--GLVKPDIVFFGEALADFSMN
SDALRAADLVIILGTSLTVYPFAALPDLCL-PKTPRLLFNLERVGTGRPDDVLVLGPCDAGVKQFAEEL----------
>tr|A0A0L0N0W5|A0A0L0N0W5_9HYPO NAD-dependent protein deacetylase hst2-1 OS=Tolypocladium ophioglossoides CBS 100239 GN=TOPH_07612 PE=4 SV=1
-------------------------------------GDKKRIVVLAGAGISTAAGIPDFRSPTGLYNNLYAEAVFDIDFFRKHPEP---FYVLAQELY-
PGKFHPTVSHVFIALLAQK-GLLQMLFTQNIDCLERRAGVHKIVEAHGSFATQRCIECKTEFPDDKMVGKVPQCMDCG--GTVKPDIVFFGEPLEEFIKN
SIHTSMADLMLIIGTSLSVYPFAALPELPR-DDMPRVLFNMEKVGKSRTDDVIQLGAVDDSIRKLADEL----------
>tr|A0A0M8N574|A0A0M8N574_9HYPO NAD-dependent protein deacetylase hst2-1 OS=Escovopsis weberi GN=ESCO_004044 PE=4 SV=1
----------------------------------ITSGAVKRIVVLTGAGISTAAGIPDFRSPTGLYHNLYAEAVFDISYFRERPEP---FYILAKELY-
PGHFHPTVSHAFIALLARK-RLLSRLFTQNIDCLERRAGVDAIVEAHGSFATQRCIECAAPFPDADMVGRVPRCPACPARGLVKPDITFFGEALPAFSEQ
SHAVAMADLVLVVGTSLSVFPFARLPEMARD-AVPRVLFNLERVGSGARADVLELGACDDGVRRLADLL----------
>tr|G9N2U3|G9N2U3_HYPVG Uncharacterized protein OS=Hypocrea virens (strain Gv29-8 / FGSC 10586) GN=TRIVIDRAFT_194055 PE=4 SV=1
----------------------------------IKSGNARRIVVLTGAGISTAAGIPDFRSPTGLYSNLYAEAVFDISYFRNHPEP---FYVLAQELY-
PGKFHPTVSHAFIALLAEK-GLLQMLFTQNIDCLERAAGVHKIVEAHGSFATQRCIECKVEFPDADMVGDVPHCNEC--KGLVKPDITFFGEALPDFSEK
SHNTVMADLVLIIGTSLTVYPFASLPEMARK-EVPRVLFNMEKVGSGSRVDVLELGACDDGIRKLANLL----------
>tr|M1VD20|M1VD20_CYAME NAD-dependent deacetylase sirtuin 1 OS=Cyanidioschyzon merolae GN=CYME_CMT600C PE=4 SV=1
----------------------------TLSDVVSLLRNSENILVLCGAGISTSLGIPDFRSEGGIYERDDPQMLFDLDQFLVDPRPFYEFAAEIF----
PPERKPSFCHRFIAQLERS-GKLLRCYTQNIDGLERAAGISRTIFCHGSFDTLRCVKCNRSRAICEQIGNVIYCERCPE-PVMKPGIVFFGEPLPFFDSI
EDDLRRADMLLVIGTSLQVAPVADMPRSLD-ASVPQILVNREVVARAIQFDVELLGDCDFIVRLIAELLGW--------
>sp|Q54GV7|SIR2D_DICDI NAD-dependent deacetylase sir2D OS=Dictyostelium discoideum GN=sir2D PE=2 SV=1
------------------------------EKVCQLFESSKNIVIITGAGVSVSCGIPDFRSKGGVYETPRPESLFDIHYLRANPLPFFEFAKEIF----
PGNHKPSPTHSFIKLLDEK-GKLLRNYTQNIDTLEHVAGIEKLVNCHGSFSTATCITCKLTVDGTTMKMEIPLCQQCNDQSFMKPDIVFFGENLDRFDQC
LKDVKDIDLLIVMGSSLQVQPVSLLPDIVD-KQIPQILINRELVAQPHEFDYVYLGDCDQFVQDLLNKV----------
>tr|F1A483|F1A483_DICPU Putative uncharacterized protein (Fragment) OS=Dictyostelium purpureum GN=DICPUDRAFT_84948 PE=4 SV=1
------------------------------DKVIELFQNSKNIVIITGAGVSVSCGIPDFRSKGGVYETPQPESLFDIHYLKSNPRAFFEFAKEIW----
PGSHRPSPTHHFIKKLEVE-GKLLRNYTQNIDTLEHVAGIEHLVNCHGSFKSATCITCNYNVPADDMKMEIPYCKKCSDSSFMKPDIVFFGESLDRFDQC
VQDIKKVDLLVVMGSSLQVQPVALLPDILD-KNVPQILVNREIVAQPHEFDYVYLGDCDSFVNELSAKL----------
>tr|F4Q4Y0|F4Q4Y0_DICFS NAD(+)-dependent deacetylase OS=Dictyostelium fasciculatum (strain SH3) GN=sir2D PE=4 SV=1
------------------------------DDVVNLFKTCKNILIITGAGVSVSSGIPDFRSKGGVYETPEPECLFDIHYLLQDPNPFFEFAKEIY----
PGRHKPSPTHYFIKELDER-GLLLRNYTQNIDTLEHVAGIEKLVNCHGSFSTASCISCKFTVDCSQDRQQIPYCQQCDDKSFMKPNIVFFGENLDRFDHC
REDRPKVDMVIVMGSSLKVQPVSLLPEYIN-PNVPQILINREIVGQPHQFDYAYLGDCDTFVKEMKEKL----------
>tr|D3BEI1|D3BEI1_POLPA NAD+-dependent deacetylase OS=Polysphondylium pallidum GN=sir2C PE=4 SV=1
------------------------------EDAVNLISKCKNIVVVTGAGVSVSCGIPDFRSKGGVYDTPEPESLFDIRYLREDPRPFFEFAKEIY----
PGSHKPSPTHYFLKKLDEH-GKLLRNYTQNIDTLEHIVGIEKLVNCHGSFKTATCVTCNTMVEGAAMKQEIPYCVNCNNTSFMKPDIVFFGENLDRFDQC
GLDRDNVDLLIVMGSSLKVQPVALIPEILD-SKIPQILINREIVGQPHEFDYVYLGDCDNFVKEIDNKV----------
>tr|C5DEF2|C5DEF2_LACTC KLTH0C08690p OS=Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284) GN=KLTH0C08690g PE=4 SV=1
-----------------RMRLANF---HTLDDFCDKLKTAKKVLVLTGAGISTSLGIPDFRSSEGFYSKDDPQDVFNYEIFMQDPSV---FYNIAHMVL-
PPENLFSPLHSFIRMIQDK-GKLLRNYTQNIDNLESYAGIEKMVQCHGSFATASCVTCHWKLPGEKNIMELPLCPYCYHYGVLKPDITFFGEALPKFRFI
RDDVMKCDLLICIGTSLKVAPVSEIVNMIPA-SVPQVLINKDPVRH-AEFDLSLLGFCDDVAALVTQKCG---------
>tr|G0VK49|G0VK49_NAUCC Uncharacterized protein OS=Naumovozyma castellii (strain ATCC 76901 / CBS 4309 / NBRC 1992 / NRRL Y-12630) GN=NCAS0I02150 PE=4 
-----------------RLKLPYF---STLDNFVDKLKNSKKVLVLTGAGVSTSLGIPDFRSSEGFYSKDDPQDVFNYEIFMQDPSV---FYNIANMVL-
PPENIYSPLHSFIKVLYDK-GELLRNYTQNIDNLESYAGIEKLIQCHGSFATASCVTCHWHLPGEKNILELPLCPYCYEYGVLKPDITFFGEALPKFESI
REDILQCDLLICIGTSLKVAPVSEIVNMLPA-SVPQVLINRDPVRH-AEFDLSLLGYCDDIAALVTEKCG---------
>tr|W6MWU3|W6MWU3_9ASCO Uncharacterized protein OS=Kuraishia capsulata CBS 1993 GN=KUCA_T00003844001 PE=4 SV=1
-----------------RRRIPSY---NTIEQFVETLEKAQNVLVLTGAGISTSLGIPDFRSSQGFYSQTDPQEVFDIDFFREDPSI---FYSIAKMIL-
PPDHSFTPMHGFIKLLEQK-GKLLRNYTQNIDNLEANAGIEKVVQCHGSFASATCVTCGYKTPGENDISRVPICPLCSKYGVMKPDITFFGEALPRFNCI
REDMSKCDLLICVGTSLKVAPVSEVVNLIPS-HVPQVLINKYPVKH-YEFDVSILGFCDPVIAHICNKLG---------
>tr|G3AN37|G3AN37_SPAPN Putative uncharacterized protein OS=Spathaspora passalidarum (strain NRRL Y-27907 / 11-Y1) GN=SPAPADRAFT_61518 PE=4 SV=1
-----------------RSRLENV---TTVTDVVNLIQNSDKIMVITGAGISTSLGIPDFRSSQGFYSMSDPQEVFDLRLFHADPSL---FYSIAYMIL-
PPENIYSPLHSFIQVLQSK-GKLLRNYTQNIDNLESYAGIDKLVQCHGSFATATCVTCGVTVPGETEIKEIPYCPPCTKFGVYKPDITFFGEPLPLFDRI
NHDIQQCDLLISIGTSLKVAPVADIVDKLPQ-TTPQILINKDPIDH-CNFDVSLLGYCDDVASYLSNELG---------
>tr|A3GHS5|A3GHS5_PICST NAD-dependent histone deacetylase (Fragment) OS=Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11
-----------------RERLDNV---RTIDDVLDQIQGASKILVITGAGISTSLGIPDFRSSKGFYSMSDPQEVFDLEIFHADPSL---FYSIAYMIL-
PPEEIFSPLHSFIKVLQSK-GKLLRNYTQNIDNLESYAGIDKLIQCHGSFASATCVTCKYQVKGETQIKEIPYCPKCIKFGVFKPDITFFGEPLPAFDSI
GYDLGECDLLISVGTSLKVAPVADIVDKVPE-NVPQILINKDPIDH-CNFDVSLLGYCDDVASFLANRLG---------
>tr|K0KVG1|K0KVG1_WICCF NAD-dependent histone deacetylase SIR2 OS=Wickerhamomyces ciferrii (strain F-60-10 / ATCC 14091 / CBS 111 / JCM 3599 / NBRC 079
-----------------RTRLDDI---HTVEHALEKISKAQKILVLTGAGISTSLGIPDFRSSKGIYSKTDPQEVFDLETFREDPTI---FYSVANMIL-
PPLDSYTPLHAFIKNLNDQ-GKLLRNYTQNIDNLESNVGIDKIIQCHGSFATATCQTCRWNIDGSKYIMELPICPHCFKYGVMKPDITFFGEDLPKFNSI
KQDVLNCDLLICIGTSLKVAPVSEIVNMIPG-DVPQILINKDLVEH-SEFDVSLLGYCDQVATYLCDKLG---------
>tr|J5S1E1|J5S1E1_SACK1 SIR2-like protein OS=Saccharomyces kudriavzevii (strain ATCC MYA-4449 / AS 2.2408 / CBS 8840 / NBRC 1802 / NCYC 2889) GN=YDL042
-----------------RLRLSNF---FTVDHFVQKLHTAQKILVLTGAGVSTSLGIPDFRSSEGFYSRDDPQDVFNYNIFMHDPSV---FYNIANMVL-
PPENIYSPLHSFIKMLQAK-GKLLRNYTQNIDNLESYAGIDKLVQCHGSFATATCVTCHWNLPGERKILELPLCPYCFKYGVLKPDITFFGEALPKFKSI
REDILECDLLICIGTSLKVAPVSEIVNMVPA-HVPQVLINYDPVKH-AEFDLSLLGYCDDVAAMVAQKCG---------
>tr|G0WE49|G0WE49_NAUDC Uncharacterized protein OS=Naumovozyma dairenensis (strain ATCC 10597 / BCRC 20456 / CBS 421 / NBRC 0211 / NRRL Y-12639) GN=NDA
-----------------RLRLSNF---YTVDHFVNALKTSKRILVLTGAGVSTSLGIPDFRSSEGFYSRDDPQDVFNYDIFMQDPSV---FYNIAHMVL-
PPDNLYSPLHSFIKLLQDK-NKLLRNYTQNIDNLESNAGIENLVQCHGSFATASCVTCHWKVPGEKNILELPLCPYCYKYGVLKPDITIFXKSLPKFRTI
KEDILKCDLLICIGTSLKVAPVSEIVNMVPA-HVPQILINRDPVRH-AEFDVNMLGFCDDVAALVAQKCQ---------
>tr|I2H5I4|I2H5I4_TETBL Uncharacterized protein OS=Tetrapisispora blattae (strain ATCC 34711 / CBS 6284 / DSM 70876 / NBRC 10599 / NRRL Y-10934 / UCD 7
-----------------RLPLSSF---SHPSSIIPILLSAKNIIVLTGAGVSTSLGIPDFRSSEGFYSRDDPQDVFSLDIFRKDPSV---FYSIAHLVL-
PPQRMFSPLHAFIKLLQDR-GSLLRNYTQNIDNFESHAGVDKLVQCHGSFATATCFTCGWKIAGERNIMELPLCPHCIDFGVLKPDITFFGESLPRFSLL
RKDLEKCDLLLCIGTSLKVAPVSDIPKLLND-NVPRFLINRDPVSH-GQFDINLLGLCDDTAVYLSKLCN---------
>tr|G0VCX8|G0VCX8_NAUCC Uncharacterized protein OS=Naumovozyma castellii (strain ATCC 76901 / CBS 4309 / NBRC 1992 / NRRL Y-12630) GN=NCAS0C03490 PE=4 
-----------------RLRLSNF---YTIEHFVDKLKTANRILVLTGAGVSTSLGIPDFRSSEGFYSKDDPQDVFNYDIFMQNPSV---FYNISHMIL-
PPDNIYSPLHSFIKMLQDK-GKLLRNYTQNIDNLESYAGIENLVQCHGSFATASCITCHWKLPGEKNIMELPLCPYCYKYGVLKPDITFFGEALPKFKTI
REDILKCDLLICIGTSLKVAPVSEIVNMVPA-HVPQVLINRDPVRH-AEFDLNLLGFCDDVAALVAQKSG---------
>tr|A7TQE2|A7TQE2_VANPO Putative uncharacterized protein OS=Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294) GN=Kpol_479p29 PE=4 SV=1
-----------------PLRRPHY---MTIEKFIAKLKSAKKIIVLTGAGISTSLGIPDFRSSEGFYSKDDPQDVFNLQIFRENPSV---FYNIAYMVL-
PPENIFSPLHSFLKLLQDK-DKLLRNYTQNIDNLESYAGIEKMVQCHGSFATASCFSCHLNVPGEKSIVTLPLCPVCYDFGVMKPDITFFGEPLPKFNSI
EKDVKGCDLLICIGTSLKVSPVSDIVNMVPQ-HVPQILINKDPIRH-CNFDLSLLGYCDDIAAYISKLCD---------
>sp|Q757M7|SIR2_ASHGO NAD-dependent histone deacetylase SIR2 OS=Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) GN=SIR2 PE
-----------------RIRLANF---FTLDHFISKLKSAKKVLVLTGAGISTSLGIPDFRSSKGFYSQDDPQDVFNLDIFMENPSV---FYTIAEKIL-
PPEHKFSPLHSFIKMIQDK-GKLLRNYTQNIDNLESYAGIENIVQCHGSFATASCVTCHLKMPGERQIREIPLCAYCYPFGVIKPDITFFGEALPEFTNI
RQDVLQCDLLICIGTSLKVAPVSEIVNMVPA-HVPQVLINRDPVKH-AEFDLTLLGLCDDVAAFIAQKCG---------
>tr|A0A0A8LAG7|A0A0A8LAG7_9SACH WGS project CCBQ000000000 data, contig 00010 OS=Kluyveromyces dobzhanskii CBS 2104 GN=KLDO_g4301 PE=4 SV=1
-----------------RIRLTNF---HTVDDFVAKLKTAKKIIVLTGAGISTSLGIPDFRSSEGFYSKNDPQDVFSLEVFTEDPSV---FYNIAHMVL-
PPENLYSPLHSFIKMIQDK-DKLLRNYTQNIDNLESYAGVEKMVQCHGSFATASCVTCHWKIQGERNILQLPICPYCYSFGVLKPDITFFGEALPKFRLI
KEDVLQCDLLICIGTSLKVAPVSEIVNMIPA-HVPQVLINKDPVKH-AEFDLSLLGLCDDVAALVAQKCG---------
>tr|C5MB00|C5MB00_CANTT NAD-dependent histone deacetylase SIR2 OS=Candida tropicalis (strain ATCC MYA-3404 / T1) GN=CTRG_03242 PE=4 SV=1
------------------------EDVTTLDDALELIAKSNKILVITGAGISTSLGIPDFRSSKGFYSMSDPQEVFDLELFHIDPSL---FYSIAHMIL-
PPEKMFSPMHSFIRVLQDH-GKLLRNYTQNIDNLESYAGIEKLVQCHGSFATASCVTCGYRINGEDKIKEIPLCQQCTKYGVFKPDITFFGEALPNFDHI
REDILECDLLICAGTSLKVAPVSDIVDKVPE-KIPQILINKDSITH-CNFDVSLLGYCDEVVSYVADKLGVEWDL----
>tr|C4XZ95|C4XZ95_CLAL4 Putative uncharacterized protein OS=Clavispora lusitaniae (strain ATCC 42720) GN=CLUG_01277 PE=4 SV=1
------------------------ENFYTVEHVLDKLRTAKKILVITGAGISTSLGIPDFRSSKGFYSRSDPQEVFDLDIFRTDPSI---FYSIAYMIL-
PPDNVYAPLHRFIKLLQDK-NKLLRNYTQNIDNLEANAGIDKMIQCHGSFAFSTCVTCGYQVPGETLMKEIPYCPMCAKYGVMKPNITFFGEALPVFDNI
NRDLADCDLVISIGTSLKVAPVADIVDKVRP-EVPQILINKDPIQH-CNFDVSLLGYCDDVVSYLCHRLGSEWAI----
>tr|G3B989|G3B989_CANTC SIR2-domain-containing protein OS=Candida tenuis (strain ATCC 10573 / BCRC 21748 / CBS 615 / JCM 9827 / NBRC 10315 / NRRL Y-149
------------------------QTFYSIDHVLEKIKSSNRILVITGAGISTSLGIPDFRSSKGFYSQSDPQEVFDLDFFRQDPSI---FYSIAHMIL-
PPTGAFTPLHEFIKLLESK-NKLLRNYTQNIDNLEENVGLSKVVQCHGSFANATCMTCKYKVPLEADIKTPSLCPRCEKYGVFKPDITFFHEKLPRFDLI
KQDILECDLLISIGTSLEVAPVADIVKRLPG-TVPQVLINKTPILH-NEFDVSLLGCCDDVASFLCMKLG--WEL----
>tr|A0A0L0P3T0|A0A0L0P3T0_9ASCO Uncharacterized protein OS=Candida auris GN=QG37_02221 PE=4 SV=1
------------------------ENFYTVEHALDKIKSAQKVLVITGAGISTSLGIPDFRSSKGFYSRTDPQEVFDLEIFHTDPSI---FYSIAHMIL-
PPDNIYAPLHKFIRLLQDK-GKLLRNYTQNIDNLEANAGIEKMIQCHGSFAHATCVTCGYKVPGETNMKEVAYCPHCAKYGVMKPDITFFGEALPAFDTI
NQDLRECDLIISIGTSLKVAPVADIVDKVPA-DVPQILINRDPIHH-CNFDISFLGYCDDVAAYLCNRLGPDWAL----
>tr|G8XZF0|G8XZF0_PICSO Piso0_005596 protein OS=Pichia sorbitophila (strain ATCC MYA-4447 / BCRC 22081 / CBS 7064 / NBRC 10061 / NRRL Y-12695) GN=Piso0
------------------------DDVYSVDHVLDKIKSANRILLITGAGISTSLGIPDFRSSQGFYSQSDPQEVFDLDFFHTDPNI---FYSIAYMIL-
PPEKTYTPMHAFIRLLQDK-GKLLRNYTQNIDNLEMYAGIDKLVQCHGSFATATCVTCKYKVNGEDSIKVIPYCPKCDKYGVMKPDITFFGESLPRFDII
RQDLADCDLLISVGTSLKVAPVASIVESIPP-GIPQVLLNRDPIDH-CSFDVTLLGYCDDAASYLCNRLGEEWNL----
>tr|M3JC93|M3JC93_CANMX NAD-dependent histone deacetylase SIR2 OS=Candida maltosa (strain Xu316) GN=G210_5371 PE=4 SV=1
------------------------DDVCTVDDALNLISKSNKILVITGAGISTSLGIPDFRSSRGFYSMSDPQEVFDLELFHVDPSL---FYSIAHMIL-
PPEQMFSPMHSFIKVLQDK-GKLLRNYTQNIDNLESYAGIENLVQCHGSFATASCVTCGVQVDGEEQIKTIPVCPDCTKYGVFKPDITFFGEALPNFDHI
REDILECDLLICAGTSLKVAPVSDIVDKVPE-KIPQILINKDPIDH-CHFDVSLLGYCDDVASYIANKLGESWSL----
>tr|A5DSX8|A5DSX8_LODEL NAD-dependent histone deacetylase SIR2 OS=Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL
------------------------PTAKTFEDALDLIQKSHKILVITGAGISTSLGIPDFRSSQGFYSMSDPQEVFDLLIFNSDPSL---FYSIAHMVL-
PPENTFSPLHSFIYLLQQK-GKLLRNYTQNIDNLESYAGIEKMVQCHGSFATATCVTCRNTVAGETTIKEIPYCPRCEAYGVYKPDITFFGEALPRFDLI
NTDISECDLLISIGTSLKVAPVADIVDKIPQ-NIPQILINRDPIDH-CNFDISLLGYCDDVAALISHRLGDDWKL----
>tr|Q6BPH5|Q6BPH5_DEBHA DEHA2E13596p OS=Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) GN=DEHA2E13596g PE=4 SV=2
------------------------DDFYCVEHVVDQIKKAKKILVVTGAGISTSLGIPDFRSSKGFYSQSDPQEVFDLDFFHSDPNI---FYSIAYMIL-
PPEKSYTPLHAFIKLLQNK-GKLLRNYTQNIDNLESNVGIEKLIQCHGSFATASCVTCKYQVKGEKKIKEVPYCPKCKNYGVMKPDITFFGEPLPRFNMI
RQDLMECDLLISIGTSLKVSPVADIVERIPE-HIPQVLINKDPIDH-CNFDVSILGYCDDTANYLCKRLGKGWEL----
>tr|A0A0A3ED99|A0A0A3ED99_CANAX NAD-dependent histone deacetylase SIR2 OS=Candida albicans P78048 GN=MG3_00919 PE=4 SV=1
------------------------EDITTINDALKLIENSKNIMVITGAGISTSLGIPDFRSSQGFYSMSDPQEVFDLDLFLNDPNI---FYSIAHMIL-
PPNHIYSPLHSFIKLLQDK-NKLLRNYTQNIDNLESYAGIENLIQCHGSFATASCITCGYKVDGEIEIKEIPYCPKCNEFGVMKPDITFFGEQLPNFIAI
NQDINKVDLVLVIGTSLKVAPVADIVGKIPE-HIPQILLNKDPINH-CQFDVSLLGYCDDVASYIANELGESWDL----
>tr|A0A0G4LIT3|A0A0G4LIT3_9PEZI Uncharacterized protein OS=Verticillium longisporum GN=BN1708_003532 PE=4 SV=1
----------------------------------IKAGKAERIVVMTGAGISTAAGIPDFRSPTGLYANPYAEAVFDIDYFRKHPEP---FYCLAKELY-
PGHFHPTVSHAFIALLAHK-GLLLMNFTQNIDCLERRAGVDLIIEAHGSFATQRCIACQAPFPDDAMDEVVPRCADCSGGGLVKPDIVFFGEALPRFRDN
THLAARADLVLVLGTSLSVYPFAGLPEHAP-PGVPRLLLNRERVGRVRADDVVELGACDDGVRRLAALL----------
>tr|A0A0F4Z951|A0A0F4Z951_9PEZI Uncharacterized protein OS=Thielaviopsis punctulata GN=TD95_003959 PE=4 SV=1
----------------------------------IKKGKAKKIVVLTGAGISTAAGIPDFRSPTGLYNNPYPEAVFDIDFFRKHPEP---FYVLAKELY-
PGKFFPTISHAFIALLAHK-KLLSKLFTQNIDCLERRAGVSLIIEAHGSFATQRCIECKSEFPEKEMAGIVPRCGKCK--GLVKPDIVFFGEGLPEFTLN
THLAREADLILVLGTSLTVYPFAGVADMPP-RETPRVLFNREQVGNMRPDDVLELGPCDQGIRRLARLL----------
>tr|M1W9Q2|M1W9Q2_CLAP2 Related to NAD-dependent histone deacetylase OS=Claviceps purpurea (strain 20.1) GN=CPUR_00756 PE=4 SV=1
----------------------------------VKSGSPKQIVVLAGAGISTSAGIPDFRSPTGIYSHPDAEAVFDIDFFRENPLP---FYCLARELY-
PGKFYPTVSHAFLALLAKK-GVLLKVFTQNIDCLERRVGVEKIVEAHGSFATQRCIDCKKEFPDREMDATVPYCKDCR--GIVKPDIVFFGEAMPLFRDN
CQYPATADVILVMGTSLSVAPFSATPDMAP-GGTPRVLINKERVGSLRTDDVLLLGTCDDGVRKFADEL----------
>tr|A7RLD5|A7RLD5_NEMVE Predicted protein (Fragment) OS=Nematostella vectensis GN=v1g179325 PE=4 SV=1
---------------------------------------------MAGAGISTPSGIPDFRTPTGLYDNLEPTAIFDIEYFWYDPRP---FFCLAKTLY-
PGNYQPNYVHYFVKLLHDK-GFLLRMYTQNIDGLERLAGLEKLVEAHGTFSTASCISCHHSYDGEQENGDIPRCEKCK--GVIKPDVVFFGEDLKRFYSF
EIDFRKCDLLLVMGTSLEVEPFAGIVNEVSR-STPRVLINRESVGPLRPKDVVLKGDIVSSVKRLAKLL----------
>tr|A9V9C1|A9V9C1_MONBE Predicted protein OS=Monosiga brevicollis GN=28881 PE=4 SV=1
---------------------------------------------MAGAGISTSAGIPDFRSPTGLYDNLYPEAIFTLDYLRSKPEA---FFTLAKELY-
PGNFDPTPCHYFIKLLQDK-GVLLRHYTQNIDTLERAAGVDLLVEAHGSFAQAACIDCSHRHDTEWDKDAVPRCESCG--GIVKPSIVFFGEDLRRFGQL
SEDFEKCDLLIVLGTSLTVHPFAGLATMPKP-EVPRLLINRDSVGEDTNRDARYLGSCDDGVWHLARGL----------
>tr|R7T6P1|R7T6P1_CAPTE Uncharacterized protein OS=Capitella teleta GN=CAPTEDRAFT_162715 PE=4 SV=1
---------------------------------------------MTGAGISTGSGIPDFRTPTGLYDNLQPQAIFDRNYFEGNPRP---FLTLAKELY-
PGKYQPNSIHYFLRLLHEK-GLLLRVYTQNIDGLERMAGILKIVEAHGSFQTASCIRCRQPHSPDEMSGSIPRCRGCL--GLVKPDIVFFGEDLKRFFYY
LKDFPQADLLIVMGTSLEVEPFAEIVDSVRH-YIPRILFNRVAVGPRRMNDVCSLGDLDTNVTYFAKML----------
>tr|A0A0Q3Y7K5|A0A0Q3Y7K5_ALLMI Sirtuin (Silent mating type information regulation 2-like protein) 3 isoform A OS=Alligator mississippiensis GN=SIRT3 PE=4 SV=1
-------------------------------------KECSRVVVMAGAGISTPSGIPDFRSPGGLYSNLYPEAIFELSYFFHNPKP---FFTLAKELY-
PGNYKPNYAHYFLRLLHDK-DLLMRLYTQNIDGLERVAGINSLVEAHGTFATATCTVCRRTYPGEDEADKIPHCPVCT--GLIKPDIVFFGEELPRFFLH
MTDFPMADLLFVIGTSLEVEPFASLAGAIR-SSVPRVLINRDLVGPQQYNDIAQLGDVVSGVEKLVELL----------
>tr|V8NFU8|V8NFU8_OPHHA NAD-dependent deacetylase sirtuin-3, mitochondrial (Fragment) OS=Ophiophagus hannah GN=SIRT3 PE=4 SV=1
-------------------------------------KECHRIVVMAGAGLSTPSGIPDFRSPGGLYSNLYPEAIFELSYFFQNPKP---FFRLAKELY-
PGNYRPNYAHYFLRLLFDK-GLLLRLYTQNIDGLERVAGIDKLVEAHGTFASATCTVCRRSYSGEDDTDKIPKCPVCT--GVVKPDIIFFGEELPRFFLH
LTDFPMADLLFIVGTSLEVEPFASLAGAVR-GSVPRVLINRDLVGPSQHNDVAELGDVISGVEKVVELL----------
>tr|L5K7W9|L5K7W9_PTEAL NAD-dependent deacetylase sirtuin-3, mitochondrial OS=Pteropus alecto GN=PAL_GLEAN10000357 PE=4 SV=1
-------------------------------------GGCPRVLVMVGAGISTPSGIPDFRSPGGWYSNLYPEAIFELPFFFHNPKP---FLALAKKLY-
PGHYRPNVIHYFLRLLHDK-GLLLRLYTQNIDGLERASGISKLVEAHGSFASATCTVCRRTSPGENDVDRVPRCSVCT--GIVKPDIVFFGEPLPRFWLH
VVDFPMADVLLILGTSLQVEPFASLSEAVR-NSVPRVLINRDVVGPPRSRDVVQLGDLVHSVEKLVELL----------
>tr|K9J567|K9J567_DESRO Putative sirtuin 5 (Fragment) OS=Desmodus rotundus PE=2 SV=1
-------------------------------------QACQTVVVMVGAGISTASGIPDFRSPGGVYSTLYPEAIFELSFFLDNPRP---FFAWAKDMY-
PGNFRPNVIHYFLRLLHDR-GLLRRLYTQNIDGLERASGISKLVEAHGSFSSATCTVCGKASPEQDAADRVPRCTVCT--GLVKPDVVFFGEALPRFFLH
VVDFPTAELLLILGTSLKVEPFASLSEAVR-SSVPRVLINREAVESPRSRDVVQLGDLVDSVERLVELL----------
>tr|A0A024FZX8|A0A024FZX8_9STRA Uncharacterized protein OS=Albugo candida GN=BN9_008500 PE=4 SV=1
-----GVRLVQPSIP-ARQKLSHVNTF---DDVIDVLRNAKKILVLAGAGISVSCGIPDFRSENGIYSRLNPQCMFDIDYFRSNPRPFFAFAKQLFPDKD
RLTFVPSQSHYFLKLLEDK-GKLLRVYSQNIDMLEHAAGIERSVLCHGSFATATCLACKRKYPNSADIQCVPMCAHCGSEGIIKPDIVFFGEPLPRFDSI
KRDENDVDLVLVMGSSLKVNPVRSIVGRIRK-DAPMILINREPVGRPHQFDVELLGYSDDIVQELCRRLDWKL------
>tr|W2LAA3|W2LAA3_PHYPR Uncharacterized protein OS=Phytophthora parasitica GN=L914_08266 PE=4 SV=1
-----GIRLIKPAATRPREKLDSVNTL---QDVASLLRSSKKIVVLAGAGISVSCGIPDFRSENGIYSRLNPQCMFDIEFFRSNPKPFFAFAKELFPKSS
GFTFVPSPSHYFLKLLEEK-GKLLRIYSQNIDMLEHAAGIEHAVLCHGSFATATCLACKRTYPNDADVQRVPMCQSCNSDGIVKPDIVFFGESLPRFDSV
KSDEGEADLVLVMGSSLKVNPVRSIVGRFKK-DTPMILINREPVGRPHKFDVELLGYSDEIVQELCRLLGWEI------
>tr|A0A0L0H9S1|A0A0L0H9S1_SPIPN Uncharacterized protein OS=Spizellomyces punctatus DAOM BR117 GN=SPPG_09397 PE=4 SV=1
-----------------RPKRPDINTL---EQAIELLRTCKNIMVLTGAGVSVSCGIPDFRSKNGIYSRLDPQQMFDIEYFRIQPQTFYSFAR---EIY-
PSNFKPSPSHLFIKLLEEK-GKLLRNYTQNIDTLEQVAGIKRVVQCHGSFATAKCIVCGYKVPGDADIKKVPMCPVCGEDGIMKPDITFFGEMLPEFDRL
FADKEKVDLLIVMGSSLKVSPVADVKDKIP-HHVPQILINMESLPH-MGFDIHLLGYCDTICAQLCRMLGWDLK-----
>tr|A0A068RL82|A0A068RL82_9FUNG Sir2-domain-containing protein OS=Lichtheimia corymbifera JMRC:FSU:9682 GN=LCOR_02601.1 PE=4 SV=1
-----------------RNRLEHVNTL---EDVVSLLAKANNVMIVTGAGVSVSCGIPDFRSETGIYSRLDPQQMFDIKYFRENPQIFYSFAK---ELY-
PSNYEPSPSHLFVKLMEEK-GKLLRNYTQNIDTLEHKANIKRIVNCHGSFATASCVTCGYKCDGKEYIQKVPPCPKCAVISVMKPDITFFGESLPEFDRL
LADTEVVDLLIVMGSSLKVSPVSEIMSQIP-HSVPQILINRTPITH-MTFDMQLLGDCDVIVPELCRMLGWDLR-----
>tr|A0A0M9VQ57|A0A0M9VQ57_9BASI Nad-dependent histone deacetylase OS=Malassezia pachydermatis GN=Malapachy_0877 PE=4 SV=1
---------------------------------------------MAGAGISTSAGIPDFRSPTGLYASLYPEALFDINYFRKNPKP---FYTLFEELYP
-DKYRPTITHCFFKLLDKK-GKLLRVFTQNIDTLEHLSGLERIVEAHGSFAKARCMECKTKVSKNEASGEVARCEMPTCVPAIKPDITFFGENLPRFFRR
ISDFHRADLLLVMGTSLVVQPFASLIDEVPA-YCPRALFNLEKVGEGETRDIFCQGKVDDTIRALAELC----------
>tr|A0A0B7NHA4|A0A0B7NHA4_9FUNG Uncharacterized protein OS=Parasitella parasitica GN=PARPA_12221.1 scaffold 44939 PE=4 SV=1
---------------------------------------------MSGAGISTAAGIPDFRSKTGLYHNLYAEAVFDIEYFLEKPEP---FYALAKELYP
-GKFLPTKTHYFIQLLQKK-GVLLRNFTQNIDTLERMTGLDYIIEAHGSFATASCVECDTKADSERLDGKVPHCEEC--NQLIKPDITFFGENLPRFFEN
LHDFEAADLLIIIGTSLQVQPFASLIDDVPP-HVPRLLINKELAGVHSDRDVAYLGTCDEGVDKLAALL----------
>tr|A0A0C7C545|A0A0C7C545_9FUNG Putative NAD-dependent deacetylase sirtuin 2 OS=Rhizopus microsporus GN=RMATCC62417_12791 PE=4 SV=1
---------------------------------------------MTGAGISTAAGIPDFRSKTGLYHNLYAEAVFDIDYFEENPQP---FYTLAKELYP
-GQFLPTKTHYFIKLLQEK-GILLRNFTQNIDTLERLTGLDYIVEAHGSFATASCIKCKNPAEIDRKAGKVPKCVFC--KGLVKPNITFFGESLPRFFNR
LIDFEKADLLIVIGTSLQVQPFASLIDEVPD-HVPRLLINRELVGVHSNRDVAYLGSCDEGVQKLAELL----------
>tr|I1CLY9|I1CLY9_RHIO9 Uncharacterized protein OS=Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880) GN=RO3G_14180 PE=4 SV=1
---------------------------------------------MTGAGISTAAGIPDFRSKTGLYHNLYAEAVFDIDYFKETPEP---FYALAKELYP
-GRYLPTKTHYFIKLLQEK-GLLLRNFTQNIDTLERMTGLEYIVEAHGSFATASCIECKTKANSDRKAGKVPRCEDC--KGLIKPDITFFGESLPRFHDH
LSDYEKADLLIVIGTSLQVQPFASLIDDVAD-TVPRLLINRELVGCYSNRDASYLGSCDEGIEKLANLL----------
>tr|A0A068S0N4|A0A068S0N4_9FUNG Nad-dependent protein deacetylase sirtuin-2isoform 2 OS=Lichtheimia corymbifera JMRC:FSU:9682 GN=LCOR_06942.1 PE=4 SV=1
---------------------------------------------MSGAGISTAAGIPDFRSKTGLYDNLYPEAIFDIEYFPEKPEP---FYALAKEIYP
-GKFYPTKTHYFIRLLHEK-GLLLRNFTQNIDTLERLAGLDLIVEAHGSFATASCIECNEKADTERKKGEVARCEEC--DGLIKPDITFFGENLPRFFDL
LDDFDEADLLIVIGTSLQVQPFASLIDNARD-DTPRLLINKELAGVYSKRDVAHLGDCDVGVEELASLL----------
>tr|C3Y212|C3Y212_BRAFL Putative uncharacterized protein OS=Branchiostoma floridae GN=BRAFLDRAFT_125988 PE=4 SV=1
------------------------------SQLVDIVCESQHLVVHTGAGISTSAGIPDFRGPKGVWTLEQKGE---------TPHF----D------TT
FESACPSPTHMALVELERL-GIVKYVISQNVDGLHVRSGFDKLSELHGNMFVEQCDKCGKQYVRDTVVPTGGQCTRCR--GKLHDTILDWEDSLPDLTLA
DEHSRRADVALVMGSSLQIVPSGNLPLLTKRRGGKLVIINLQASKHDKHADLRIHGYVDEVMSMVMNRLGIN-------
>tr|X5HY17|X5HY17_POLMI Sirtuin 6 OS=Polyandrocarpa misakiensis GN=PmSIRT6 PE=2 SV=1
------------------------------DALTSLLKESKCTVVHTGAGISTSSGIPDFRGPKGVWTLEEKGL---------EPEC----N------IR
FDEAVPSYTHRVLVELESA-GLVHYVVSQNVDGLHVRSGFDRLSELHGNMFIQICNKCKRDYVMNYVSPTGVKCTKCR--GNLHDSILDWEDSLPELDRA
DTMSRAATLSLTLGTSLQILPAANLPLHAKKNNGTLVVVNLQPTKHDRRADLRIHYYVDDVIKGVMENLGIK-------
>tr|A0A0B6ZQJ5|A0A0B6ZQJ5_9EUPU Uncharacterized protein OS=Arion vulgaris GN=ORF72827 PE=4 SV=1
------------------------------DQLASLVRCSKHIVVHTGAGISTSAGIPDFRGPKGVWTLEEKGE---------SPQF----D------IT
FDSAEPTATHMALVALERA-GIVKYVVSQNIDGLHLKSGFNRLSELHGNMFIEECNKCGYQYIKKYCVPTGGSCTTCR--GKLIDTILDWENSLPDLNTA
VEQCKKSDLTICLGTSLQILPSGNIPLLTKKNGGKIVIVNLQPTKHDKKCDLKIAAYVDDVMRRLCEALDVD-------
>tr|R7UXV9|R7UXV9_CAPTE Uncharacterized protein OS=Capitella teleta GN=CAPTEDRAFT_150121 PE=4 SV=1
------------------------------QQLASWIRESRHFVVITGAGISTSCGIPDFRGPQGVWTKEQRGE---------EVKF----G------VT
FEEARPSQTHMALVAMERK-GFLKHVISQNVDGLHLRSGFDRLSELHGDMFVEDCEHCHTQYIRTNIVPTGQTCTRCR--GRLRDTILDWEDALPDAVAA
EENCKIADLCLCLGTSLQIVPCGNYPMLTKRNKGKIAIVNLQTTKQDRNAQLRIHAYVDTVLLKVCQELKIS-------
>tr|A0A0L8FVN7|A0A0L8FVN7_OCTBM Uncharacterized protein OS=Octopus bimaculoides GN=OCBIM_22006578mg PE=4 SV=1
------------------------------LQLTTLIRESKHVVFHTGAGISTSAGIPDFRGPKGVWTLEMRGE---------EPKV----D------IT
FESAKPTLTHMALVALEKA-GFVHFLISQNIDGLHLRSGFNRLAELHGNMFVEECDKCFIQYISESSVPTGDNCLICR--GQLTDTILDWEDNLPDLQAA
NKEAKLADLSVCLGTSLQIKPSGRIPVLTKKNGGKLVLVNLQPTPLDRLCDLRINAYVDRVMKGVCQLLDVD-------
>tr|G0QYJ9|G0QYJ9_ICHMG Sir2 family histone, putative OS=Ichthyophthirius multifiliis (strain G5) GN=IMG5_150240 PE=4 SV=1
----------------------EKTKKFSRQKLVEGFQTFKNVVFLTGAGISVSAGIPDFRTPTGLYSQPYPEAVFTLAYFRKNPLP---FYKLAKEFLQ
-CRAHFTINHYFMAKVYQQ-GALLANFTQNIDGLEIEAGIEKIIQAHGHFRSARCIDCSEKVEIEKEKEEILKCEKCN--GLIKPDIVFFGEQLPEFIQK
VKLLKQADLVIIMGTSLVVQPFSSLVEFID-SKVPLVLINRENNVVKNDSFLFIEGDLDNNVRLLLKDIG---------
>tr|H2KTG0|H2KTG0_CLOSI NAD-dependent deacetylase sirtuin-2 OS=Clonorchis sinensis GN=CLF_102963 PE=4 SV=1
----------------------PKLTSVDLEGIAELIKAVKNIVTMAGAGISTAAGIPDFRSPSGLYDNPYPMAVFTIDYFVENPEP---FFKVAKGLYR
-PEAKPTLTHYFFRLLHEK-KLLRRHYTQNVDDLERLTGLDKLIEAHGTFHTGHCITCKKLYSLEFSNDKIPKCKSCD--GVVKPDIVFFGEALPKFHTN
VNDFSVCDLLIIIGTSLTVAPFCMLVDKVG-ADVPRLYINREVPEMGNKTDVFFRGDADDGVQHLSELLG---------
>tr|W5M391|W5M391_LEPOC Uncharacterized protein OS=Lepisosteus oculatus PE=4 SV=1
------------------------------QDVARFIQEYKRIVVMAGAGISTPSGIPDFRSPSGLYDNLYAEAIFEINYFRHNPKP---FFALAKELY-
PGNYLPNLTHFFIRLLHDK-GLLHRMYTQNIDGLERMAGISKLVEAHGTFATATCTVCRTSYPGEAEISKIPKCPSCK--GVLKPDIVFFGEELPQFFLY
LTDFPMADLLIVMGTSLEVEPFASLAGAVR-SSVPRVLINRDLVGYPRPNDVVEQGDVITGVQKFVDTL----------
>tr|W5UDY9|W5UDY9_ICTPU NAD-dependent protein deacetylase sirtuin-3, mitochondrial OS=Ictalurus punctatus GN=SIRT3 PE=2 SV=1
------------------------------EDIAKGIREYKRIVVMAGAGISTPSGIPDFRSPSGLYDNLYAEAIFEINYFNHNPKP---FFALAKELY-
PGNYRPNLAHYFIRLLHDK-GQLLRMYTQNIDGLERMAGIVKLVEAHGTFATATCTVCRREYQGEDDIGTVPHCSQCK--GVIKPDVVFFGEELPHFFLY
LTDFPIADLLIVMGTSLEVEPFASLSSAVR-GSVSRLLINRDLVGWSRYSDVAELGDVVSGVRKLADTL----------
>tr|Q2H5A0|Q2H5A0_CHAGB Putative uncharacterized protein OS=Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970) GN=C
----------------------------------IKSGQARRIVVMTGAGISTAAGIPDFRSPTGLYANLEPEAVFDLSFFRQNPQP---FYVLARELYP
-GRYRPTISHAFLALLARR-GLLHMLFTQNIDCLERAAGVDRIVEAHGSFASQRCVDCKGEFDGE----------------VMRAF-VARGEVPRAFFEF
SGMTKEADLILVMGTSLQVHPFAGLPNMAEE-ETPRVLFNLEEVGSGRADDVMVLGDCDAGVRKLAEELG---------
>tr|A0A090CF94|A0A090CF94_PODAN Putative NAD-dependent deacetylase sirtuin-2 HST2 OS=Podospora anserina (strain S / ATCC MYA-4624 / DSM 980 / FGSC 10383) PE=4 
----------------------------------ILSGRAKRIVVMTGAGISTAAGIPDFRSPTGLYANLEPEAVFDLGFFKVNPRP---FYVLAKELYP
-GNYHPTVSHVFVRLLAEK-GLLHQLFTQNIDCLEREAGIEKIIEAHGSFASQRCIECKTEFDAG----------------KMREF-VSQGELPKAFFDR
RDMAEEADLVLVMGTSLQVHPFAGLVDLAAE-RVPRVLFNLERVGSGQADDVLALGDCDEGVRRLADELG---------
>tr|G2R0D0|G2R0D0_THITE Uncharacterized protein OS=Thielavia terrestris (strain ATCC 38088 / NRRL 8126) GN=THITE_68068 PE=4 SV=1
----------------------------------IKSGRARRIVVMTGAGISTAAGIPDFRSPTGLYANLEPEAVFDLGFFRQNPAP---FYALARELYP
-GRYRPTIAHVFVALLARK-GLLRMLFTQNIDCLERAAGVHLVVEAHGSFATQSCIDCKAPFDGE----------------RMRAC-VARGELPRDFFEK
SAAVKEADLILVMGTSLQVHPFAGLPNMADP-EVPRVLFNLQQVGSGRADDVMVLGDCDAGVRMLADELG---------
>tr|K1X4R8|K1X4R8_MARBU NAD-dependent deacetylase sirtuin-2 OS=Marssonina brunnea f. sp. multigermtubi (strain MB_m1) GN=MBM_06261 PE=4 SV=1
----------------------------------IKSGRPKRIVVMTGAGISTSAGIPDFRSETGLYANLHPEAVFDISFFRERPEP---FYVLAKELYP
-GRFYPTVSHAFIALLSEK-RMLTMLFTQNIDCLERQAGVDKIVEAHGSFASQRCIECKTEYPED----------------QMKEA-VEEGRLPASFFQH
RDLPMTADLIIVMGTSLSVQPFASLPSMAGD-GVPRVLINKEKVGDGRLDDVEILGECDEGVRELADALG---------
>tr|J9Z4N1|J9Z4N1_SPOSC SIR2 OS=Sporothrix schenckii GN=SIR2 PE=2 SV=1
----------------------------------ILDGKVRRIVALTGAGISTAAGIPDFRSPTGLYANLYAEAVFSIDYFRENPHP---FYILAKELYP
-GQFHPTVAHAFLSLLAAK-GLLRMLFTQNIDCLERAAGVDLIVEAHGSFATQRCIDCRTSFPDD----------------EMREH-VRDARLPQRFHEL
GKLPADADLVLVLGTSLTVYPFAGLPTMVPD-HVPRVLFNREVVGDGRADDVLELGSCTAGVLKLADALG---------
>tr|M7UNR4|M7UNR4_BOTF1 Putative nad-dependent deacetylase sirtuin-2 protein OS=Botryotinia fuckeliana (strain BcDW1) GN=BcDW1_2901 PE=4 SV=1
----------------------------------IKSGKAKNIVVMTGAGISTSAGIPDFRSPTGIYANLYAEAVFDIDFFRENPAP---FYVLAKELYP
-GQFYPTVSHAFVALIEKK-GLLRMLFTQNIDCLERRAGVEKVIEAHGSFATQRCIDCKTEYPDD----------------MMKKA-IEDGDLPEAFHAN
KMIPATADLVIVMGTSLSVQPFATLPTLAPE-TVPRLLFNMISVGDGRLDDVAILGDCDSGVRKLADALG---------
>tr|K3UJU0|K3UJU0_FUSPC Uncharacterized protein OS=Fusarium pseudograminearum (strain CS3096) GN=FPSE_07580 PE=4 SV=1
----------------------------------IKSGRSKNIVVLTGAGISTAAGIPDFRSPTGLYANLYAEAVFDISYFREHPEP---FYVLANELYP
-GKFHPTVSHAFIALLARK-QLLQMLFTQNIDCLERVAGVDRIIEAHGSFAKQRCIECKEEYPDD----------------KMKEH-VFGGKLPKAFDNN
TFQVAMADMVLVVGTSLSVYPFAALPGLAQE-GKPRVLFNMEQVGQGRSDDVIELGDCDAGIRKFADELG---------
>tr|A0A016THA2|A0A016THA2_9BILA Uncharacterized protein OS=Ancylostoma ceylanicum GN=Acey_s0102.g3468 PE=4 SV=1
----------------RREKLSAYNTF---EDAVELFRTRKRILILTGAGVSVSCGIPDFRSKDGIYARPDPTAMFDIRYFTHNPAPFYDFAMEI---F-
PGQFEPSVSHKFIRQLEVN-NQLLRNYTQNIDTLEKQAHIERVVECHGSFAKATCLNCSAKFDGDDDVKRVAHCPRCTV-GVIKPDIVFFGEDLGDFSQM
AIDKDEVDLLVVIGSSLKVRPVSLIPFSVN-PNVPQILINREPLS-GYRADIELLGNCDEIIEDICLALGG--------
>tr|H3F9R1|H3F9R1_PRIPA Uncharacterized protein OS=Pristionchus pacificus GN=WBGene00108481 PE=4 SV=1
----------------KRIKLINYNTF---QDAVELFRKSKRILMLTGAGVSVSCGIPDFRSKDGIYSRPDPSAMFDIQYFRRNPKPFYDFAKEI---F-
PGMFEPSFSHKLIAHLEKS-DKLLRNYTQNIDTLEKVAGIERVIECHGSFSSASCINCNAVYTPDENVKTVAYCRVKCD-GVIKPNIVFFGEDLHDFTQM
AIDKHEADLVVVIGSSLKVRPVSLIPFAVS-PDVPQILINREPIG-HYTSDIELLGNCDDILREIAIQMGE--------
>tr|A0A0N4XY74|A0A0N4XY74_NIPBR Uncharacterized protein OS=Nippostrongylus brasiliensis PE=4 SV=1
----------------TRNKLPQYNTF---EDAVELFRHRKRILVLTGAGVSVSCGIPDFRSKDGIYARPDPTAMFDIRYFNTNPAPFYDFASEI---F-
PGQFEPSISHKFIRQLEVN-GQLLRNYTQNIDTLEKQANIEKVVECHGSFSKATCLKCHAKFDGDEDVKRVAHCPHCTD-GVIKPDIVFFGEELDTFTQM
AADKDELDLLVVIGSSLKVRPVSLIPFSVD-HNVPQILINREPLS-GYRADIELLGNCDEIIEDICIALGG--------
>tr|A0A0N5CMG6|A0A0N5CMG6_THECL Uncharacterized protein OS=Thelazia callipaeda PE=4 SV=1
--------------RPKRIRLPQFNSF---DDAVELFRRCNRILVLTGAGVSVSCGIPDFRSKNGVYARPDPTAMFDIKYFQKNPKPFFEFARE---LF-
PGRYRASLCHYFIKALEDD-EKLLRNYTQNIDTLEQVAGIKRIVQCHGSFATATCRSCGVKVDSEEDIGRVAMCRICNQEGVLKPDIVFFGEDLDDFEKM
AEDRNKVDLVVVIGSSLKVQPVALLPYNVGE-KVPQILINRESLPH-YSTDIELLGNCDDIVTQLALALG---------
>tr|A8PZF9|A8PZF9_BRUMA NAD-dependent deacetylase SIRT1, putative OS=Brugia malayi GN=Bm1_38355 PE=4 SV=1
--------------RPKRTKLSEFNSF---DDAVELFKRCSRILVLTGAGVSVSCGIPDFRSRNGVYARPDPTAMFDINYFSKNPKPFFEFARE---LF-
PGRYEASMCHYFIKALEDS-GKLLRNYTQNIDTLEQVAGIKRIVQCHGSFATATCRNCGLKVDSEEDIGRVAMCRVCSHEGVMKPDIVFFGEDLDDFEKM
AEDREMVDLVVVIGSSLKVQPVALLPYNINP-EVPQILINRESLPH-YATDIELLGNCDDIVAQLALVLG---------
>tr|A0A0B2VX43|A0A0B2VX43_TOXCA NAD-dependent protein deacetylase sir-2.1 OS=Toxocara canis GN=sir-2.1 PE=4 SV=1
--------------RPRRDKLLGYNTF---DDAVELFRRSRRILVLTGAGVSVSCGIPDFRSKDGIYARPDPTAMFDINYFVQNPKPFFEFARE---IF-
PGQFEASICHYFIKVLEIE-GKLLRNYTQNIDTLEQVAGITRIVQCHGSFSKATCRHCGSKFDGNEDVKRIAMCQRCGDKGVLKPDIVFFGEDLDEFDRM
VEDKSEVDLVVVIGSSLKVQPVALIPFSVDA-SVPQILINREPLPH-YTADIELLGNCDDIITQIALALG---------
>tr|G8C0V3|G8C0V3_TETPH Uncharacterized protein OS=Tetrapisispora phaffii (strain ATCC 24235 / CBS 4417 / NBRC 1672 / NRRL Y-8282 / UCD 70-5) GN=TPHA0M
----------------TRIRLSNFSSP---MDFVNRLKEAKNILVLTGAGVSTSLGIPDFRSSEGFYSKDDPQDVFNFDIFMQDPSV---FYNIAHLVL-
PPDNICSPLHSFIKMLQDK-GKLLRSYTQNIDNLESYAGIEKLVQCHGSFATASCVTCHWQLPGEKIIMELPLCPYCYPCGVLKPDITFFGEALPKFKTI
RKDILECDLLICIGTSLKVAPVSEIVNMLPA-HVPQVLINKDPVKH-AEFDISFLGLCDDVVAYITEL-----------
>tr|A0A0D4GC41|A0A0D4GC41_YEASX Hst1p OS=Saccharomyces cerevisiae YJM1356 GN=HST1 PE=4 SV=1
----------------TRLRLPNFNTI---DHFTATLRNAKKILVLTGAGVSTSLGIPDFRSSEGFYSKEDPQDVFNLDIFLQDPSV---FYNIAHMVL-
PPENMYSPLHSFIKMLQDK-GKLLRNYTQNIDNLESYAGIDKLVQCHGSFATASCVTCHWQIPGEKIILELPLCPYCYQYGVLKPDMTFFGEALPRFKTI
RKDILECDLLICIGTSLKVAPVSEIVNMVPS-HVPQILINRDMVTH-AEFDLNLLGFCDDVASLVAKK-----------
>tr|Q2UZW1|Q2UZW1_CANGB NAD-dependent histone deacetylase OS=Candida glabrata GN=SIR2/HST1 PE=4 SV=1
----------------TRIRLSNFYTI---DHFVSKIKKAERILVLTGAGVSTSLGIPDFRSSEGFYSKDDPQDVFNYDIFMQDPSV---FYNIAHMIL-
PPENMYSPLHSFIKMLQDK-GKLLRNYTQNIDNLESYAGIEKLVQCHGSFATASCVTCHWQIPGEKIIMELPLCPYCYQYGVLKPDITFFGEALPKFKTI
REDIMKCDLLICIGTSLKVAPVSEIVNMIPA-YVPQVLINKDPVKH-AEFDIELLGFCDDVATVVAQK-----------
>tr|J7RCF8|J7RCF8_KAZNA Uncharacterized protein OS=Kazachstania naganishii (strain ATCC MYA-139 / BCRC 22969 / CBS 8797 / CCRC 22969 / KCTC 17520 / NBR
----------------TRVKLSNFTTV---DDFASRLQSASNVIVLTGAGVSTSLGIPDFRSSEGFYSKQDPQDVFNYEIFRRDPSV---FYSIAHMVL-
PPSGIYSPLHSFIKMLADK-NKLLRNYTQNIDNLEAAAGVEKLVQCHGSFATASCVTCHWKVPGEKVIVELPLCPYCVQYGVLKPDITFFGEALPKFKSL
REDIPKCDLLVCIGTSLKVAPVSDIVSMLPI-DVPQVLINRDPVKH-AEFDLSLLGYCDDIASLVTDS-----------
>tr|J7S399|J7S399_KAZNA Uncharacterized protein OS=Kazachstania naganishii (strain ATCC MYA-139 / BCRC 22969 / CBS 8797 / CCRC 22969 / KCTC 17520 / NBR
----------------TRLRLANFFTL---DHFVDKLQSANKILVLTGAGVSTSLGIPDFRSSQGLYSRDDPQDVFNYDIFMQDPSV---FYNIAHLVL-
PPENIYSPLHSFIKLLQDK-GKLLRNYTQNIDNLESYAGIEKLVQCHGSFATASCVTCHWQLPGEKIIMELPLCPYCYQYGVLKPDITFFGEALPKFRTI
REDIDKCDLLICIGTSLKVAPVSEIVNMVPA-HIPQVLINRDPVKH-ANFDLNLLGLCDDVAALVSQK-----------
>tr|C5DR31|C5DR31_ZYGRC ZYRO0B05148p OS=Zygosaccharomyces rouxii (strain ATCC 2623 / CBS 732 / NBRC 1130 / NCYC 568 / NRRL Y-229) GN=ZYRO0B05148g PE=4 
----------------TRLRLSNFTTP---DAFVERLQSAKSILVLTGAGVSTSLGIPDFRSSEGFYSKEDPQDVFNYDIFMQDPSV---FYNIAHLVL-
PPENIYSPLHGFIKMLQDK-GKLLRNYTQNIDNLESYAGIEKVVQCHGSFATASCTTCHWKLPGDKIILELPLCPYCYMHGVLKPDITFFGEALPKFKTI
REDILKCDLLVCIGTSLKVAPVSEIVNMVPS-HVPQILINRDPVKH-AEFDLNLLGYCDDVATLIAQK-----------
>tr|H2ARV5|H2ARV5_KAZAF Uncharacterized protein OS=Kazachstania africana (strain ATCC 22294 / BCRC 22015 / CBS 2517 / CECT 1963 / NBRC 1671 / NRRL Y-82
----------------TRISLSNFYTL---DHMVAKLKTAKRIIVLTGAGVSTSLGIPDFRSSEGFYSKDDPQDVFNLDIFLQDPSV---FYNIAHLVL-
PPENIYSPLHSFIKMLQDK-GKLLRNYTQNIDNLESYAGIEKLVQCHGSFATASCITCHWQLPGEKIIMELPLCPYCYHYGVLKPDITFFGEALPKFKTI
REDVLKCDLLLCIGTSLKVAPVSEIVNMLPA-HVPQILINRDPVKH-AEFDIDLLGFCDDVAALVAQK-----------
>tr|H2AWR0|H2AWR0_KAZAF Uncharacterized protein OS=Kazachstania africana (strain ATCC 22294 / BCRC 22015 / CBS 2517 / CECT 1963 / NBRC 1671 / NRRL Y-82
----------------TRIRLLSFNRI---EDLVTKLHSASNIIVLTGAGVSTSLGIPDFRSSEGFYSQDDPQEVFSYDHFMRDPSI---FYSIAKMVL-
PPENMYSPLHSFIKMLHDK-GKLLRNYTQNIDNLESYAGIERLIQCHGSFATASCVTCHFQLPGEKIIVEVPLCPYCYDYGVIKPDITFFGEALPKFKSI
RHDLTQCDLLICIGTSLKVAPVSEIVNMLPA-HVPQVLINRDPVKH-TDFDLSLLGYCDDIASAITQK-----------
>tr|Q6FNA6|Q6FNA6_CANGA Uncharacterized protein OS=Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) GN=SIR2 PE=4 SV=1
----------------TRLRLMNFFTI---DHLVERLEKAKRIVVLTGAGISTSLGIPDFRSSEGFYTKEDPQDVFNYEIFLRDPSV---FYNIANMVL-
PPENIYSPLHSFIKLLQDK-RKLLRNYSQNIDNLESYAGISKLIQCHGSFATASCVTCKWSLPGEKIIFEIPLCPHCYKFGVIKPDITFFGEPLPRFKTV
KEDIFRCDLLLCIGTSLKVAPVSEIVNMLPA-HVPQVLINRDPVRH-AEFDISLLGYCDDIATMIAQK-----------
>tr|I1CN02|I1CN02_RHIO9 Uncharacterized protein OS=Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880) GN=RO3G_14543 PE=4 SV=1
---------TRYLRKRR--RLDYVNTL---EDVVELLRKANNVMIVTGAGVSVSCGIPDFRSETGIYSRDDPQQMFDIEYFRETPEIFYSFAKE---LY-
PANYEPSPSHLFVKLVEEK-GKLLRNYTQNIDTLEHKANIKRVVNCHGSFATASCVTCGYKVDGKEFAQQVPPCPRCVVGCIMKPDITFFGERLPEFDNL
LLDTEHVDLLIVMGSSLKVSPVSEIMQQIP-HSIPQILINRTPIT-HMTFDIQLLGDCDIIVPEICRMLQWDLKHP---
>tr|A0A0C9N735|A0A0C9N735_9FUNG SIR2-domain-containing protein OS=Mucor ambiguus GN=MAM1_0355d09984 PE=4 SV=1
---------THYLRKRR--RLDYVNTL---DDVADLLSKANNIMIVTGAGVSVSCGIPDFRSEKGIYSRDDPQQMFDIEYFRESPEIFYSFAKE---LY-
PAKYQPSPSHLFVKLVEEK-GKLLRNYTQNIDTLEHKTNIKRVVNCHGSFATASCVTCGYKVDGKEFAQKVPPCPKCLQVSIMKPDITFFGEQLPEFDNL
LVDTEQVDLLIVMGSSLKVSPVSEIMSQIP-HSVPQILINRTPIT-HMTFDIQLLGDSDVIVPELCRMLNWDLRHP---
>tr|G0RC35|G0RC35_HYPJQ NAD-dependent histone deacetylase OS=Hypocrea jecorina (strain QM6a) GN=TRIREDRAFT_120404 PE=4 SV=1
------------------------------DDAVRLIDKSQNIIVITGAGISTSLGIPDFRSQGGLYSKSDPQEVFDIEVFKQDPTI---FYSVAKDIIP
-STDRFTPTHKFIAMLHER-GKLLTNYSQNIDNLEIKAGLEKLIQCHGSFGTASCVQCRYQIEGEKDIGKIPRCTRCLSAGVMKPDITFFGEELDEFSRL
ENDRDKVDLVIVIGTSLKVTPVSEIASFLPP-HIPQIYISRQSVTH-INFDIDLLGDCDVVVAELCRQLKWPLV-----
>tr|N4VNU8|N4VNU8_COLOR Histone deacetylase OS=Colletotrichum orbiculare (strain 104-T / ATCC 96160 / CBS 514.97 / LARS 414 / MAFF 240422) GN=Cob_07726
------------------------------DDAVELLQRSRNIIVLTGAGISTSLGIPDFRSKGGLYSQNDPQEVFDISVFKQDPTI---FYTVAKDILP
-STNRFTPTHAFISMLQQK-GKLLTNYTQNIDNLEAKAGIDKMIQCHGSFATATCVQCGFKCVGEEDIGKIPRCPRCIQVGVMKPDITFFGEALDEFSRL
EHDRDKVDLVIVIGTSLKVTPVSEIVSWLPP-NIPQLYISRQAVNH-INFDIDLLGDCDVVVSELCRRAGWPLK-----
>tr|A0A084QIB5|A0A084QIB5_9HYPO Uncharacterized protein OS=Stachybotrys chlorohalonata IBT 40285 GN=S40285_08496 PE=4 SV=1
------------------------------GDAVELINKSNNIILITGAGISTSLGIPDFRSKGGLYSKSDPQEVFDIGMFKQDPTI---FYSVAKDIIP
-STDRYTPTHKFIAMLHER-GKLLTNYSQNIDNLEIKAGVDKLIQCHGSFGTATCVECGYKTDGEDDIGNIPRCPRCVEAGVMKPDITFFGEALDEFSRL
VHDRDKVDLVIVIGTSLKVTPVSEIVSWLPP-HIPQIYVSRQAVTH-INFDIDLLGDCDVVVAELCRRLKWPLK-----
>tr|A0A0P7BAR8|A0A0P7BAR8_9HYPO NAD-dependent protein deacetylase hst1 OS=Neonectria ditissima GN=AK830_g9096 PE=4 SV=1
------------------------------EDAVDLIQNSKNIILLTGAGISTSLGIPDFRSKGGLYSKSDPQEVFDIDVFRQDPTI---FYSVAKDILP
-STDRYTPTHKFIAMLNER-GKLLTNYSQNIDNLEVKAGVEKLIQCHGSFGTATCVQCGYQMEGEKEIDKIPRCPRCIQAGVMKPDITFFGEALDEFSRL
ENDRDKVDLVVVIGTSLKVTPVSEIVSWLPS-HVPQIYISRQAVSH-INFDIDLLGDCDVVVTELCRRLGWPFK-----
>tr|T5AJI2|T5AJI2_OPHSC NAD-dependent histone deacetylase OS=Ophiocordyceps sinensis (strain Co18 / CGMCC 3.14243) GN=OCS_01527 PE=4 SV=1
------------------------------DDAVGLLARCSNIVVITGAGISTSLGIPDFRSKGGLYSKNDPQEVFDIDLFRQDPSI---FYSVAREIVP
-ATDRHTPTHRFIAMLHQR-GKLLTNYSQNIDNLEVKAGLDKLVQCHGSFGTASCVQCAFQIQGDTDIGNIPRCPRCLEAGVMKPDITFFGEALDEFSRL
EHDRDKVDLVVVIGTSLKVTPVSEIVSWLPP-HIPQLYVSRQAVNH-INFDIDLLGDCDVVVAELCRRLDWPLE-----
>tr|A0A0L9SGN6|A0A0L9SGN6_9HYPO Uncharacterized protein OS=Ophiocordyceps unilateralis GN=XA68_997 PE=4 SV=1
------------------------------DDAVRLMDRCSNIVVITGAGISTSLGIPDFRSKGGLYSKNDPQEVFDIDVFKQDPSI---FYSIAKDIVP
-ATDRFTPTHQFIAMLHQR-GKLLTNYSQNIDNLEVKAGLDRLVQCHGSFGSATCVQCGHGMPGDAHIGQVPRCPRCLKAGVMKPDITFFGEPLDEFSRL
EHDRDKVDLVVVIGTSLKVTPVSEIVSWLPP-QIPQIYISRQPVNH-INFDIDLLGDCDVVVAELCRRLHWPLR-----
>tr|A0A0F7ZJU0|A0A0F7ZJU0_9HYPO NAD-dependent protein deacetylase hst1 OS=Hirsutella minnesotensis 3608 GN=HIM_06026 PE=4 SV=1
------------------------------DDAVSLINKCSNIIVITGAGISTSLGIPDFRSKGGLYSKNDPQEVFDIDVFKQDPTI---FYSVAKDIVP
-ATDRYTPTHKFIAMLHQR-GKLLTNYSQNIDNLEIKAGLDKLIQCHGSFGTASCVQCGYQIQGEKDIGNIPRCPRCTQAGVMKPDITFFGEALDEFSRL
ENDRDKVDLVVVIGTSLKVTPVSEIVSWLPP-HIPQVYVSREAVSH-INFDIDLLGDCDVVVAELCHRLGWPFE-----
>tr|N1QKG5|N1QKG5_SPHMS SIR2-domain-containing protein OS=Sphaerulina musiva (strain SO2202) GN=SEPMUDRAFT_146700 PE=4 SV=1
--------VTRAFYKRKKLT--QYNTV---DDAARLIKESHKIIVITGAGISTSLGIPDFRSKTGFYDKYEPQDVFDIYEFDRDPTL---FYDLAGDILP
DQKLGVTPTHAFIKLLQDK-GQLRRNYTQNIDDLESLAGIDKTIQCHGSFATASCRKCKTKVDGKADIQRVAHCQKCIAPGVMKPDITFFGEQLPFFHRF
THDSKITDLVIVIGTSLKVAPVSEMPHHFN-RNTPHIYISMEPIKH-VEFDIQLLGKSDDVVVELCRRAGWNLKHEKV-
>tr|M2NNY5|M2NNY5_BAUCO Uncharacterized protein OS=Baudoinia compniacensis (strain UAMH 10762) GN=BAUCODRAFT_144801 PE=4 SV=1
--------ITRTYYKRRKLA--HVNTI---DDAANLLRNSNKILVITGAGISTSLGIPDFRSKSGFYDKYEPEEVFDIQNFDEDPSI---FYRLAGDIMP
DLN-RYSPTHAFIKLLQDK-GRLQTNYTQNIDNLEELAGISRLIQCHGSFATATCRKCGDRVAGSEDIKRVARCKQCQNAGVMKPDITFFGEQLNFFNRF
TRDQKETDLVIVIGTSLQVKPVSELPQYVP-AEVPLIYVSKQQIEH-INFDIQLQGECDHVVYELCRRAGWKLEHEMI-
>tr|A0A0F4GWY9|A0A0F4GWY9_9PEZI Uncharacterized protein OS=Zymoseptoria brevis GN=TI39_contig287g00011 PE=4 SV=1
--------IFRAYYKRKKLP--QYNTI---DHVAALVQRSNKIMVITGAGISTSLGIPDFRSKTGFYSKYEPEEVFDIHNFDEDPSI---FYGLAGDILP
DHQ-RISPTHAFIRLLQDN-NRLQTNFTQNIDNLEALAGISRLIQCHGSFATASCRKCKHQVPGTDDIKRVPICQRCVQPGVLKPDITFFGEALPFFTRF
TIDAPTTDLVLILGTSLQVAPVSDMPNFLP-HGVPHVYVSREKLRH-VAVDVQLLGDCDVVVGELCKRLGWSLEGVEG-
>tr|N1Q3W7|N1Q3W7_DOTSN Uncharacterized protein OS=Dothistroma septosporum (strain NZE10 / CBS 128990) GN=DOTSEDRAFT_68672 PE=4 SV=1
--------IVRFYHKRSKLA--QYNTI---EDAAKLLQSSRNIMVITGAGISTSLGIPDFRSKTGFYDKYEPEEVFNIDNFDTNPEI---FYRLAGDILP
DQK-RYSPTHGFIRLLQDH-NRLQTNYTQNIDNLEELAGIDRIIQCHGSFATASCRKCKHQVKGTEDIKQVAQCKRCLEAGIMKPDITFFGEALPFFETF
TRDAQETDLVIVIGTSLKVAPVSEMPNFLP-KAVPHIYISRETIKH-VEFDIQLLGNCDDVVYELCRRAGWDLKHEMI-
>tr|A0A0G2F4D6|A0A0G2F4D6_9EURO Putative histone deacetylase OS=Phaeomoniella chlamydospora GN=UCRPC4_g00153 PE=4 SV=1
--------PDEAFYGLLKLR--QYNSV---EDAVELIRKSCNIIVVTGAGISTSLGIPDFRSKTGFYDKLEPSEVFDLNIFRTDPDI---FFSVAGDILP
PSEPQFTPTHAFIKLLEDK-QKLLTNYTQNIDNVESYAGIDKIIQCHGSFATATCQKCQYQAPGESEIKEIAYCPKCKAPGVMKPDITFFGEALPFHQRI
VEDQHKVDLVIVIGTSLKVDPVGSIPAALD-PDTPQIYISKSRCKH-IDFDIEFNGDCDLVCAELARRLEWDLKHEMV-
>tr|R7WG59|R7WG59_AEGTA NAD-dependent ADP-ribosyltransferase sirtuin-4 OS=Aegilops tauschii GN=F775_08708 PE=3 SV=1
--------------------------------LYRFIDKSNKLMVLTGAGMSTESGIPDYRSPNGAYSGFKP---LTHQEFVRSIRARRRYWAR--SYAG
WRRAQPNTAHYALASLERI-GRVHTMVTQNVDRLHH-RAGSKPVELHGSVYEVICLDCGTSISRESDIFDIPSCSQCG--GVLKPDVVMFGDNVPRADSA
KEAARNCDALLVVGSAVMTMSAFRLARLAHEANAPIAAINIGGTRADSIISLKINARCGEILPRVLQM-----------
>tr|A0A0P4U1Y5|A0A0P4U1Y5_ROSNE Putative histone deacetylase OS=Rosellinia necatrix GN=SAMD00023353_2000910 PE=4 SV=1
-----------------RAKIMAHNSV---DDAVQLLRKSRNIVVLTGAGISTSLGIPDFRSKTGLYSQNDPQEVFSIDVFRDDPTI---FYTVAKDILP
-ATKRFSPTHAFIAMLQNQ-GKLLTNYSQNIDNIEANAGIEKLVQCHGSFATASCQRCGHRVRGDTDIGKIPRCGKCVAAGVMKPDITFFGEPLPEFKRL
VHDRNLVDLVIVIGTSLKVAPVSEVVPFLPS-HIPQIYISRTPVSH-INFDIDLLGDCDVVVAELCRRAGWNLKHPMV-
>tr|M7TMF1|M7TMF1_EUTLA Putative histone deacetylase protein OS=Eutypa lata (strain UCR-EL1) GN=UCREL1_1878 PE=4 SV=1
-----------------RAKLDTYNSI---DDAVHLIQRSRNIVVLTGAGISTSLGIPDFRSKNGLYNQNDPQEVFNIEVFREDPTI---FYSVAKDILP
-ANKQFTPTHAFIAMLQNK-GKLLTNYSQNIDNIEANAGIEKLVQCHGSFANATCQRCGHQVLGDSDIGRIPRCVKCIAAGVMKPDITFFGEALPEFRRL
VHDRNIVDLVIVIGTSLKVAPVSELVPFLPP-DVPQLYISRTPVTH-INFDIDLLGDCDVVVAELCRRAGWDLQHEMI-
>tr|W3WYS8|W3WYS8_9PEZI NAD-dependent protein deacetylase hst1 OS=Pestalotiopsis fici W106-1 GN=PFICI_10314 PE=4 SV=1
-----------------RAKLMSYNTV---DDAVSLIQDAKNIIVLTGAGISTSLGIPDFRSATGLYTQNDPQEVFDIEVFRQDPTI---FYTVAKDILP
-TTKKFTPTHAFIAMLQAK-GKLLTNYSQNIDNIEANAGIEKLLQCHGSFAKATCQKCGYKVPGEADISRIPRCDRCITAGIMKPDITFFRENLPEFDRL
RRDMTRVDLVIVIGTSLKVSPVSEVVPSLPP-HVPAIYISRTPVGH-IDFDIDLLGDCDVVVAELARRAGWNLDHEMI-
>tr|R8BWJ5|R8BWJ5_TOGMI Putative sir2 family protein OS=Togninia minima (strain UCR-PA7) GN=UCRPA7_751 PE=4 SV=1
-----------------RAKLSRYNSV---DDAAELLKNSHNIIVLTGAGISTSLGIPDFRSKTGLYSKSDPQEVFDITVFRQDPTI---FYSVARDILP
-EQDRYSPTHAFIAMLQQK-GKLLTNYSQNIDNLEAKAGIDKLVQCHGSFATASCILCGYKVQGESDIGRIPRCPKCAPGGIMKPDITFFGEPLPEFRRL
THDREKVDLVIVIGTSLKVAPVSEVVPFLPP-HIPQLYISRTPVSH-VNFDIDLLGDCDVVVSELCRRAGWDLRHEMI-
>tr|H0EE33|H0EE33_GLAL7 Putative NAD-dependent histone deacetylase sir2 OS=Glarea lozoyensis (strain ATCC 74030 / MF5533) GN=M7I_0701 PE=4 SV=1
-----------------RVKLPAYNSV---DDAVELIKKSSNIIVLTGAGISTSLGIPDFRSATGLYSKNDPQEVFDISKFRENPKI---FYSVARDLIT
-DEPRTTPTHAFIALLQQK-GKLLTNYSQNIDNIEATAGIEKLVQCHGSFATASCIECRYQVPGTTSIEKIPQCPRCIEPGVMKPDITFFGEPLPRFDRL
THDKDKVDLVIVIGTSLKVAPVSEVVPFLPP-HIPQMYISREPVSH-VNFDVDMLGDCDVVVAELCERAGWELKHEMI-
>tr|D3YT50|D3YT50_CAEEL Yeast SIR related OS=Caenorhabditis elegans GN=sir-2.1 PE=1 SV=1
----------------------------SLADAVELFKTKKHILVLTGAGVSVSCGIPDFRSKDGIYARPDPTAMFDIRYFRENPAP---FYNFAREIF-
PGQFVPSVSHRFIKELETS-GRLLRNYTQNIDTLEHQTGIKRVVECHGSFSKCTCTRCGQKYDGNEEVMRVAHCKRCE--GVIKPNIVFFGEDLGEFQHV
TEDKHKVDLIVVIGSSLKVRPVALIPHCVD-KNVPQILINRESLPH-YNADIELLGNCDDIIRDICFSLGGSF------
>tr|E3M5G7|E3M5G7_CAERE CRE-SIR-2.1 protein OS=Caenorhabditis remanei GN=Cre-sir-2.1 PE=4 SV=1
----------------------------SLADAVELFKTRKNILILTGAGVSVSCGIPDFRSKDGIYARPDPTAMFDIRYFRNNPAP---FYNFAREIF-
PGQFTPSVSHRFIKELESA-GRLLRNYTQNIDTLEHQTGIKRVVECHGSFSKNTCTECGDQTDGMVDVMRVARCKKCD--GVIKPNIVFFGEDLGDFRCV
TEDKNKVDLIVVIGSSLKVRPVALIPHCVG-KDVPQILINRESLPH-YNADIELLGNCDDIIRDICFSLGGSF------
>tr|R7QMB6|R7QMB6_CHOCR Uncharacterized protein OS=Chondrus crispus GN=CHC_T00000174001 PE=4 SV=1
-------------------------------DVAKLIDDARNIVVLTGAGVSVSCGIPDFRSKGGLYDAEDPQAIFDLEEFKMDPTLFYSFAK---DVMP
SNDLRPSPTHRFIAELEAR-GKLLRNYSQNIDGLERRAGVERVILCHGSFLTATCMRASCRASISVEAGTVPLCRKCVHMGVLKPDIVFFGENLPRVDNL
ETDALRADLVLVLGTSLQVSPVARIPQYFHD-QVPRILVNRELVT--YDFDVELLGNCDSVVAELRKALSWD-------
>tr|L8HHW7|L8HHW7_ACACA NADdependent deacetylase sirtuin, putative OS=Acanthamoeba castellanii str. Neff GN=ACA1_174690 PE=4 SV=1
-------------------------------PVPSVNGASNRIMVVSGAGISVSCGVPDFRSPGGLYERTDPQAIFDFDLFRSDPTPFYSLCK---DLFP
KESLNPSPSHYFIKLLEDK-HKLLRNYTQNIDTLECKAGLKRIMHCHGSFATASCIQCAHR--VSDEADKIPKCPKCRIKNVMKPDIVFFNEPLSKFLSL
DKDLDKVDLLVVMGSSLRVQPVSIIPEEVRS-EVPQILINRELVGEPDQFDYFLQGECDSIIVEICKRLGWT-------
>tr|F2UI01|F2UI01_SALR5 Sirt3 protein OS=Salpingoeca rosetta (strain ATCC 50818 / BSB-021) GN=PTSG_08102 PE=4 SV=1
--------------------------------------NCKKVVVMAGAGISTSAGIPDFRSPTGLYDNEEPEDVFSIDFFRENPNP---FYDLAKELY-
PGHFKPTPSHHFVRLLQDK-GILLRHYTQNIDTLERMAGVDKVIEAHGSFATAHCTDCQEEADWVKFAGDIPHCQRCG--GVVKPDIVFFGESLPRFTRG
RKDLADADALIVMGTSLKVHPFASLISYARK-DVPRILINRDRVGEDGYRDVFMGGTCDDGVRVLAR------------
>tr|A0A067QKL1|A0A067QKL1_9HOMO Uncharacterized protein OS=Jaapia argillacea MUCL 33604 GN=JAAARDRAFT_187428 PE=4 SV=1
-------------------------------NISLAVAKSKKIVVMTGAGISCSCGIPDFRSSDGLYNLYKGRDLFDASLFR-DPTVFYTFISQLKRSID
--GATPSPTHAFLKTLDTK-RKLLRSYTQNIDGLEERSGLKRNVQLHGDIHRVRCTFCSAELACTEEYMQAPDCPECSAVGTLRPAIVLYDEPHPLGDQT
TDLNRKPDLLLIMGTSLKVHGFKKLVKEFAKHPGKVIFVNKTASEWEGIIDYHVMGGSDEWVTRVLEDWKR--------
>tr|S7S3G6|S7S3G6_GLOTA DHS-like NAD/FAD-binding domain-containing protein OS=Gloeophyllum trabeum (strain ATCC 11539 / FP-39264 / Madison 617) GN=GLOT
-------------------------------AVSLAVAKSKKIVVVTGAGISCSCGIPDFRSSDGLYNLYKGRDLFDSSLFR-DPTLFYTFISNLKRSID
--SAKPSPTHRFIKTLDTK-GKLLRSYTQNIDGLEERCGLKRNVQLHGDIHRVRCMLCSADLVCGEEHLEAPDCPECSAVGTLRPAIVLYDEPHPLGEQT
SDINRKPDLLIIMGTSLKVHGFKKLVKDFARHCGKVVFVNKTAPEWEGIIDYWVQADTDTWSEKTLDEWKK--------
>tr|W4KNU6|W4KNU6_9HOMO Uncharacterized protein OS=Heterobasidion irregulare TC 32-1 GN=HETIRDRAFT_308239 PE=4 SV=1
-------------------------------SLSLAVAKSKRIVVVTGAGISCSCGIPDFRSSDGLYALYRGRDLFDASLFR-DPTVFYTFVSQLKQSVD
--GAKPSPTHHFLKTLDAK-KKLLRSYTQNIDGLEERAGLKRNVQLHGDIHRVRCTFCSADLHCTEEYLLAPDCPECVAVGTLRPAIVLYDEAHPLGDQS
SDIARKPDLLIIMGTSLKVHGLKKLVKDFARNAGKVIFVNKTAPEWNGIIDYHIEGETDEWVERLLDEWRR--------
>tr|A0A060STE1|A0A060STE1_PYCCI Uncharacterized protein OS=Pycnoporus cinnabarinus GN=BN946_scf184935.g35 PE=4 SV=1
------------------------------------------------MYQTYERVSQDFRSSDGLYSLYKGRDLFDASLFR-DSTVFYTFISQLKKSID
--VASPSPTHRFIKTLDSK-KKLLRSYTQNIDGLEERAGLKRNVQLHGDIHRVRCTFCSADYPCTQEHVTAPDCPECASVGTLRPAIVLYDEPHPLGDHS
ADIARKPDMLIIMGTSLKVHGFKKLVKDFARLAGKVIFVNKTAPEWDNIIDYHVVGETDRWVEKVVEDWKK--------
>tr|A0A0K3CF82|A0A0K3CF82_RHOTO BY PROTMAP: gi|342321067|gb|EGU13005.1| putative Hst3 protein [Rhodotorula glutinis ATCC 204091] OS=Rhodosporidium toruloides G
-------------------------------AVALAVAKGKRTVLLVGAGISTNAGIPDFRSSGGLYSSLKGPDLFSASVYS-SPDEHLRFIAHFKQSLD
--DIEATATHDFMRLLKKR-GKLQRVYTQNIDGLEGVGGLKDYVQLHGSVHAVRCTSCAFVRRWTEEDVHVGACPECEERAYLRPSIVLYSESPPSSSSL
SDLSSGPDVMLVLGTSLRIPGFKKLVKEFSRRG-VRVLVNREEGEWKGVFDYEVIADTDSFVTRLIEGWKR--------
>tr|F8NF44|F8NF44_SERL9 Putative uncharacterized protein OS=Serpula lacrymans var. lacrymans (strain S7.9) GN=SERLADRAFT_444740 PE=4 SV=1
-------------------------------DISLAVAKCKKIVVVTGAGISCSCGIPDFRSSDGLYALYKGRDLFDASLFR-DSTVFYTFISQLKRSID
--SASPAPTHNFIKTLEAK-QKLLRSYTQNIDGLEERVGLKRNVQLHGDIHRVRCTFCSAEFPCIEEHLMAPDCPECFAVGTLRPAIVLYDEPHPLGDQT
ADIARKPDMLIIMGTSLKVHGLKKLVKDFAKTSGKVIIVNKTPPEWSDIIDYHVAGETDRWVERVLEDWKK--------
>tr|A0A0D0DPJ4|A0A0D0DPJ4_9HOMO Unplaced genomic scaffold scaffold_1, whole genome shotgun sequence OS=Paxillus rubicundulus Ve08.2h10 GN=PAXRUDRAFT_182675 PE=
-------------------------------NISLAVAKCKKIVVVTGAGISCSCGIPDFRSSDGLYALYKGRDLFDASLFR-DKTVFYTFVSQLKRCID
--SATPAPTHHFIKTLDTK-QKLLRSYTQNIDGLEERVGLKRNVQLHGDIHRVRCTLCSTNFPCTEDYLVAPDCPECQLVGTLRPAIVLYDEAHPLGDQT
SDIARRPDMLIIMGTSLKVHGLKRLVKDFAKSAGKVIFVNKTPPEWADIIDYHVAGETDRWAEKVIEDWKK--------
>tr|M5FRY2|M5FRY2_DACSP DHS-like NAD/FAD-binding domain-containing protein OS=Dacryopinax sp. (strain DJM 731) GN=DACRYDRAFT_95811 PE=4 SV=1
-------------------------------AISLAVAKSKRIVVVTGAGISCSCGIPDFRSSDGLYNLYKGRDLFDASLFR-SPDLFYTFIAELKNAVN
--AAEPGATHRFLRLLEGK-GKLLRSYTQNIDGLEERAGSKRNVQLHGDIHT-------------------PPCPACVSQGYLRPAIVLYDEPHPLGDQA
QDVARGPDMLIIMGTSLKVHGLKRLVKDFASRAGKVIFVNRTPPEWNEVIDFHVQGETDTWVLRVEEEWRR--------
>tr|A0A0C3KB71|A0A0C3KB71_PISTI Uncharacterized protein OS=Pisolithus tinctorius Marx 270 GN=M404DRAFT_998266 PE=4 SV=1
-------------------------------DISLSVAKCKKIVVVTGAGISCSCGIPDFRSSDGLYALYKGRDLFDASLFR-DQTVFYSFISQLKRSID
--SASPAPTHEFIKRLDNR-HKLLRSYTQNIDGLEEKAGLKRNIQLHGDIRRVRCTFCSVDLPCTEEHIVPPDCPECTSVGSLRPAIVLYDEAHPMGDQS
QDIARKPDLLIVMGTSLKVHGLKKLVKEFAKTAGKVVFVNKTPPEWSDVIDYHIMGEIDQWIEKVTEDWRR--------
>tr|J7SBU2|J7SBU2_9APHY Uncharacterized protein OS=Fibroporia radiculosa GN=FIBRA_00120 PE=4 SV=1
-------------------------------NLSLAVAKCKKVVVVTGAGISCSCGIPDFRSSDGLYALYKGRDLFDASLFR-DPTVFYTFISQLKRSID
--SASPSPTHRFIKTLDTK-RKLLRSYTQNIDALEERAGLKRNVQLHGDIHRVRCTFCSAEFSCTEEHLIPPDCPECITVGTLRPAIVLYDEPHPLGDQS
ADISRKPDMLIIMGTSLKVHGFKKLVKDFARSAGKVIFVNKTPPEWEGIIDYHVIGETDKWAERVVEEWKK--------
>tr|K9IB61|K9IB61_AGABB Uncharacterized protein OS=Agaricus bisporus var. bisporus (strain H97 / ATCC MYA-4626 / FGSC 10389) GN=AGABI2DRAFT_189378 PE=4
-------------------------------ELSKSVYKSKRIVVVTGAGISCSCGIPDVRSSNGLYALYKGRDLFDASLFR-DPIMFYTFISELKRSID
--AVTPSPTHHFIKALDAK-RKLLRSYTQNIDGLEEKVGLKRNIQLHGDIHRVRCASCSAEYPCTEEYLTAPDCPECLVVGKLRPAIVLYDEPHPLGDQT
ADAARKPDLLIIMGTSMKVHGLKKLVKDFAKSGPKVIFVNKTAPEWSDVIDYHVVGETDVWVSRVLDDWKT--------
>tr|A0A0D0B7G1|A0A0D0B7G1_9HOMO Unplaced genomic scaffold CY34scaffold_199, whole genome shotgun sequence OS=Suillus luteus UH-Slu-Lm8-n1 GN=CY34DRAFT_14190 PE
-------------------------------DISLAVAKSKKIVVVTGAGISCSCGIPDFRSSDGLYSLYKGRDLFDASLFR-DSAVFYTFISQLKRSID
--AATPAPTHQFIQTLDTK-HKLVRSYTQNIDGLEERIGLKRNVQLHGDIHRVRCTFCSTEMPCTEEHLKAPNCPECTSIGTLRPAIVLYDEPHPLGDQT
MDIARKPDMLIIMGTSLKVHGLKKLVKDFAKTGGKVVFVNKTPPEWSDIIDYHVAGETDAWVDKVLEDWKK--------
>tr|K5WPK1|K5WPK1_PHACS Uncharacterized protein OS=Phanerochaete carnosa (strain HHB-10118-sp) GN=PHACADRAFT_180496 PE=4 SV=1
-------------------------------NLSLSVAKCKKIVVVTGAGISCSCGIPDFRSSDGLYALYKGRDLFDASLFR-DATVFYTFISQLKQSVD
--RASPSPTHRFLKALDAK-GKLLRSYTQNIDGFEEQVGLKRNVQLHGDIHRVRCTLCSAEFLCTPEYLIAPDCLECASVGTLRPAIVLYDEPHPLGDQT
ADLARRPDMLIIMGTSLKVHGFKKLVKEFARTAGKVIFVNKTPPEWEGIIDIWVQGESDKWVEKVTEDWKK--------
>tr|A0A0C3PS02|A0A0C3PS02_PHLGI Uncharacterized protein OS=Phlebiopsis gigantea 11061_1 CR5-6 GN=PHLGIDRAFT_101690 PE=4 SV=1
-------------------------------NLSLSVAKCKKIVVVTGAGISCSCGIPDFRSSDGLYALHKGRDLFDSSLFR-DAKVFYTFISQLKQSID
--RASPSPTHKFLKTLDAK-RKLLRSYTQNIDGLEEQAGLKRNVQLHGDIHRVRCTFCSAEFPCTSEHLVPPDCPECLSIGTLRPAIVLYDEPHPLGDQT
ADLARRPDMLVIMGTSLKVHGFKKLVKEFARTAGKVIFVNKTPPEWEGIIDYWVEGESDTWVEKVLDDWKK--------
>tr|G4TX68|G4TX68_PIRID Related to HST3-Silencing protein OS=Piriformospora indica (strain DSM 11827) GN=PIIN_09907 PE=4 SV=1
-------------------------------SLSATVFKSRRIVVVTGAGISCSCGIPDFRSSDGLYNLYKGRDLFDASLFR-DKTVFYTFISGLKAAID
--KAEPSPTHHFLTTLDKK-GKLLRSYTQNIDGLEERSGLKKNIQLHGDIHRVRCTACSASYPCSEEHMTSPECPECKQVGHLRPAIVLYDEAHPLGDQT
TDLGKRPDLLIIMGTSLKVHGLKKLVKEFAKGSPKVIFVNKTAPEWSNIIDTHVEGTTDEWVERVTSDWKH--------
>tr|A0A0C3BQZ4|A0A0C3BQZ4_9HOMO Uncharacterized protein OS=Serendipita vermifera MAFF 305830 GN=M408DRAFT_325449 PE=4 SV=1
-------------------------------GLSSAVVKSRRIVVVTGAGISCSCGIPDFRSSDGLYNLYKGRDLFDASLFR-DKTVFYTFISGLKAAID
--KASPSPTHHFLHTLHKR-GKLLRSYTQNIDGLEERSGLKKNIQLHGDIHRVRCNVCSASFPCEEEHMTAPDCPECKQVGTLRPAIVLYDEPHPLGDQT
SDLSKRPDLLIIMGTSLKVHGLKKLVKEFAKGSPKVIFVNKTAPEWAGVIDLHVQGTSDAWVERVISDWKH--------
>tr|A0A0L6WHL0|A0A0L6WHL0_9AGAR NAD-dependent histone deacetylase HST3 OS=Termitomyces sp. J132 GN=J132_05327 PE=4 SV=1
-------------------------------DLSLSVAKNKRIIVITGAGISCSCGIPDFRSSDGLYNLYKGRDLFDASLFR-DGIVFYTFISKLKQSID
--VATPSPTHRFIKTLDTK-KKLLRSYTQNIDGLEERVGLKRNVQLHGDIHSVRCMSCSAEYPCTSDHLIAPDCSECASVGTLRPAIVLYDETHPLGDQS
ADVARKPDLLIIMGTSLKVHGLRKMVKEFAKYGGKVIFVNKTPPEWNDIIDYHVEGDTDSWVEKVIEDWKK--------
>tr|D8PSB4|D8PSB4_SCHCM Sirtuin 5 and related class III sirtuins OS=Schizophyllum commune (strain H4-8 / FGSC 9210) GN=SCHCODRAFT_269896 PE=4 SV=1
-------------------------------ELSRAVVKSTKIVVVTGAGISCSCGIPDFRSSDGLYALYKGRDLFDASLFR-DTTVFYTFISQLKQSID
--KATPSPTHHFIKALNEK-KKLLRSYTQNIDGLEERAGLKRNVQLHGDIHRVRCITCCAEQPCIPEYVIAPDCPECLKVGSLRPAIVLYDEPHPLGDQT
SDVGRKPDCLIIMGTSLKVHGLKKLVKDFAKAACKVVFVNRTPPEWAGIIDYHVEADADSWVKMTMEEWKS--------
>tr|A0A0C3CVB3|A0A0C3CVB3_HEBCY Uncharacterized protein OS=Hebeloma cylindrosporum h7 GN=M413DRAFT_209505 PE=4 SV=1
-------------------------------DISLSVAKGKKIVVVTGAGISCSCGIPDFRSSDGLYAMYKGRDLFDAALFR-DPTVFYTFISQLKRSID
--DAEPAPTHHFIKTLDSK-KKLLRSYTQNIDGLEARVGLKRNVQLHGDIHRVRCVACSADYPCSEEHLKAPECPECLSVGSLRPSIVLYDETHPLGDHT
TDLGRKPDMLIIMGTSMKVHGLKKLVKDFARSSYKVIFVNKTAPEWADIIDYHISGETDRWTNKVIEDWKK--------
>tr|V2XFU5|V2XFU5_MONRO Hst3 protein OS=Moniliophthora roreri (strain MCA 2997) GN=Moror_399 PE=4 SV=1
-------------------------------DLSLAVAKCKKIVVVTGAGISCSSGIPDFRSSDGLYNMYKGRDLFDASLFR-DPAVFYTFISKLKRSID
--SATPTPTHHFIKTLDSK-KKLLRSYTQNIDGLEERVGLKRNVQLHGDIHRVRCRSCSAEFPCLEEYLQCPDCPECLQVGQLRPAIVLYDEFHPLGDQC
SDLARKPDMLIIMGTSLKVHGLKKLVKEFAKHVGKVIFVNKTAPEWSDVIDYHVVGETDMWVDKVIEDWKK--------
>tr|A8N9A9|A8N9A9_COPC7 Hst3 protein OS=Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003) GN=CC1G_00984 PE=4 SV=2
-------------------------------DLSLAVAKRKKIVLVTGAGISCSCGIPDFRSSDGLYNLYKGKDLFDASLFR-DSTVFFSFIAELKKKID
--VAKPSATHHFIKTLDSK-NKLLRSYTQNIDGLEERVGLKRNVQLHGDIHR-----------------VAPGCPECTSVGSLRPAIVLYDEPHPLGDQT
TDLSKKPDMLIIMGTSLKVHGLKKLVKEFAKSTFKVIFVNKTPPEWSDYIDYHVQGDSDTWVNRVIEDWKR--------
>tr|A0A0H2S8U9|A0A0H2S8U9_9HOMO DHS-like NAD/FAD-binding domain-containing protein OS=Schizopora paradoxa GN=SCHPADRAFT_897958 PE=4 SV=1
-------------------------------NLSLAVAKSKKIVIVTGAGISCSCGVPDFRSSDGLYNLYKGRDLFDASLFR-DATVFYTFIAKLKQSID
--SVEPSRTHHFIKTLDNK-GKLLRSYTQNIDGLEERVGLKRNVQLHGDIRRVRCTLCSADFPFSEEYTVAPDCPDCASIGTLRPAIVLYDEPHPLGDES
SDLSRKPDLLIIMGTSLKVHGLKKLVKEFSKTGGKVIFVNRTPPEWDSIIDFHIEGDTDAWTDRVLEDWKK--------
>tr|L8HEA7|L8HEA7_ACACA Transcriptional regulator, Sir2 family protein OS=Acanthamoeba castellanii str. Neff GN=ACA1_361150 PE=4 SV=1
------------------------------ARLVDLIRDSHKIVFLTGAGVSTESGIPAFRDNGGVWGKYS-EKHELFQNFVAEEEAQVNYWRMLYAIA-
-AHAKPNPSHHIAAHLAAQ-GRLLGVLTQNIDGLYLTAGLARLVELHGTSTRARCLTCDALYPMEATVEPVPHCLAPGCGGVLKPDTISFGQRLANVTRA
RQWLDECDLLIVMGTSLRVAPVNKYPTISLNKRTPLVMANMEETMYDDFAEVLLDGRCGEMMAALQDQLQRT-------
>tr|D2VK77|D2VK77_NAEGR Putative uncharacterized protein OS=Naegleria gruberi GN=NAEGRDRAFT_80274 PE=4 SV=1
------------------------------EKIIELIQNSSKILGLTGAGISVESGISAFRNSGNSWEKWN-QDEMTYQNILSKKKIRDDYFEMLKEQI-
-SKAEPNGSHHLFAQLKEK-GKLLKVITQNIDGMHQKAGLDKVIEIHGSSRGVVCTKCRTLVEDPEKIKSLPDLVTCKCGGVLKPNTISFGEELSKLIEA
RQQCRECDLMIIMGTRLLVSPVNQLPKLVAARNVPVVIINLESTPFDRNSVAVMNGKSGETCNYILHRLTSI-------
>tr|A0A015KD97|A0A015KD97_9GLOM Hst2p OS=Rhizophagus irregularis DAOM 197198w GN=RirG_022680 PE=4 SV=1
-----------------------------------KTGKAKRIIVMAGAGISTAAGIPDFRTPTGLYDNLYPEAIFDMTYFKENPEP---FFSLAKELF-
PGNFMPTLTHYFLTLLYRK-NILLRCFTQNIDTLERLAGLEMIVEAHGSFAKSKCLKCKKFADWMKEVGEVPICTSCRV-GIVKPCITFFGEAPSKFFLR
LGDFQVCDLLIVIGTSLQVQPFASLVDSVGE-KVPRLLINLEKVGDDYMRDAFYKGTCDEGVRKLAELCG---------
>tr|I1FUE0|I1FUE0_AMPQE Uncharacterized protein OS=Amphimedon queenslandica PE=4 SV=1
-----------------------------------ASNDANRIIVMTGAGISTAAGIPDFRTPTGLYDNLSPQSIFDISYFPMNPKP---FFHLAKEMY-
PGNFKPTLCHYFIRLLETK-GLLLRSYTQNIDTLERRAGIEHLVEAHGAFHLAHCITCGKEYPYVKEQDKIPLCTETYK-GIVKPDIVFFGEAPKRFGLA
SKDLQKCDLLIVMGTSLTVQPFASLPSKVRE-DCPRLLINYEKVGEDAYRDVFLQGTCDEGVKELAKRLG---------
>tr|G8XZL4|G8XZL4_PICSO Piso0_005662 protein OS=Pichia sorbitophila (strain ATCC MYA-4447 / BCRC 22081 / CBS 7064 / NBRC 10061 / NRRL Y-12695) GN=Piso0
-------------------------------EAAKTVYKARRTVVLTGAGISCNAGIPDFRSSDGLYNMFKGQDLFDISIFRDEMTLFLSFMEQLYSFSE
--TASPTETHRFIRTLKDK-KKLLRCYTQNIDGLEQKLGLSDVVQLHGSLGHLACTSCFCNFDWNSEYRLSPDCQNCYLYGFLRPNIVLYGENHPQAESG
KDKSMRPDLLIIMGTSLRVDGVKKLVRAMHARGGKVLFVNKTPVSWSSVIDYEVLCDCDRFVELLRDEI----------
>tr|Q6BPA4|Q6BPA4_DEBHA DEHA2E15202p OS=Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) GN=DEHA2E15202g PE=4 SV=2
-------------------------------EVSKIIFKSRKAVVLTGAGISCNAGIPDFRSSDGLYNMFKGQDLFDISIFRDEVTLFCTFMESLYSSSI
--DAKPTETHRFIKILKEK-KKLLRCYTQNIDGLEDKMNLNDVVQLHGNINNLACTQCFHSFNWNVEYRSNPECKNCYLIGMLRPNIVLYGENHPQSENG
KDVNLKPDLFIIMGTSLKVDGIKRLVKTLHNRGGTVLFVNKTPISWSNIIDYEILCDCDEFVKLLKYEI----------
>tr|A0A060T7M4|A0A060T7M4_BLAAD ARAD1D00616p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1D00616g PE=4 SV=1
-------------------------------TVQREIQKSRKVVLITGAGISCNAGIPDFRSTNGLYNLYKGKDLFDTVLFSNSRSVFYSFMAALRQQIL
--QARPTSTHRFIHFLKCR-KKLLRCYTQNIDNLEAKVVHSDVVQLHGDIERLRCMLCTRQYEWFEEAETAPTCPSCMNVGSLRPDIVLYGEEHPDGDRC
QDLRANPDCLIIMGTSLKVTGIRKLTRTLKARGGICVLVNASDLSWDNVIDYHIKGDCDDWIETLRQ------------
>tr|W6MMQ2|W6MMQ2_9ASCO Uncharacterized protein OS=Kuraishia capsulata CBS 1993 GN=KUCA_T00003466001 PE=4 SV=1
-------------------------------SITSSVSKSRKVVVLTGAGISCNAGIPDFRSSEGLYNMHKGKDLFDISLFRDEDTIFCTFMEQLYSHTI
--CANPTETHKFLRRLMER-KKLIKCYTQNIDGIERKVGMEDTVQLHGDLNSLACTQCFQTYSWEEKHKEMPECPDCVAIGILRPNIILYGENHPHAERG
QDANRAPNLLLIFGTSLKVDGVKKLVRTMHEKNGLVIFINQTQISWDGIIDYQIQADCDEWIINLKKEI----------
>tr|W1QKI1|W1QKI1_OGAPD Uncharacterized protein OS=Ogataea parapolymorpha (strain DL-1 / ATCC 26012 / NRRL Y-7560) GN=HPODL_00091 PE=4 SV=1
-------------------------------QINKSISKSKKVVVLTGAGISCSAGIPDFRSAHGLYNLKKGKDLFDISLFRNDESLFCKFMQQLYTKTC
--TARPTKTHWFIRRLKKH-GKLLKCYTQNIDGLERQCDLDDVVQLHGDLNRLSCTMCFSRFAWDDESSELPDCPNCVAVGVLRPDIVLYGEHHPHADRG
SDMAKNPNLLIIFGTSLKVDGVRKLVRQLHERDGKVIFINDCEVSWDKVIDYQIKSDCDEWCEYIEKQI----------
>tr|A0A0J9XCY3|A0A0J9XCY3_GEOCN Similar to Saccharomyces cerevisiae YOR025W HST3 Member of the Sir2 family of NAD(+)-dependent protein deacetylases OS=Geotrich
-------------------------------EIAFKLAKSRKFIAVTGAGVSCNAGIPDFRSEDGLYNMYKGKDLFDAVLFSSPDTVFFTFMAHLRDCIL
--KARSTQTHKLLKVLKEK-KKLLRCYTQNIDGLETHENL-DVIQLHGDIHKLKCMHCSQLFDWTEDSTEAPECPACRIVGRLKPNIVLYGEEHPDGDRC
SDFKSKPDFLLIAGTSLKVVGIQKLVRQAKAKGGVVIFVNKTEVGWKDVIDYHIEADCDEWVTNLKTRI----------
>tr|F2QST7|F2QST7_PICP7 Similar to SIR2 family of putative histone deacetylases OS=Komagataella pastoris (strain ATCC 76273 / CBS 7435 / CECT 11047 / N
-------------------------------MINQKVSKSKKMLCLTGAGISCNAGIPDFRSNKGLYNLKKGQDLFDISLFRQEETIFNRFMHSLYEHSR
--QIQPTDTHLFIKHLYER-KKLIRCYTQNIDGLERKLGLTQIVQLHGDLHKLSCTNCSNKFSWNLEYEESPECPKCLEIGILRPNIILYGENNEYSERG
QDLNKRPNILLIFGTSLKVNGVQSLVKKIHEDKGIVIYINKTPLNWNSIVDFHIQADCDEWVQHLRANF----------
>tr|A0A0A4BW65|A0A0A4BW65_CANAX Uncharacterized protein OS=Candida albicans P57055 GN=MGK_04087 PE=4 SV=1
-------------------------------EVIKFISKSKKMTVLTGAGISCNAGIPDFRSSDGLYNMHRGQDLFDISLFRDEMSVFCTFMESLYKSSL
--NAKPTETHKFIKILKDK-NKLLRCYTQNIDCIEQHINLNDVVQLHGNLHKLSCTNCFSQFNWNEEFQLNPECSKCMDIGLLRPDIVLYGEHHPQMEQG
SDLKSRPDCLIIMGTSLKVAGVKSLVKSLHNKGGKVIYVNKTKLSWKNYIDYEVVSDCDEFVRMLKTEI----------
>tr|D8LJJ1|D8LJJ1_ECTSI Sir2-type regulatory transcription factor silent information regulator protein OS=Ectocarpus siliculosus GN=Esi_0026_0040 PE=4 SV=1
--------------------------------------AGGSVTALTGAGMSTDSGIPDYRGPKGSYSRHKP---MTHDEFLSSEDNRKRYWA--RSTFG
WDRARPNEAHVALAGLEAA-GKVDSVITQNVDGLHQKAGSRNVVNLHGRNDKVGCMSCRFESSWIADVFVVPACPRCG--GILKPTVVFFGDNIPRVEDT
YRIVDESELLIAAGSSLQVYSAYRLVKRAADAGKKVVVINLGETRAERLDILKVEAGVSNVLPKLL-------------
>tr|K7IS10|K7IS10_NASVI Uncharacterized protein OS=Nasonia vitripennis GN=LOC100118450 PE=3 SV=1
-------------------------------------NTSGKICVITGAGISTESGIPDYRSEGGLFATSDR-RPVSYQDFCKSDKTRRRYWA--RNYAA
WPLFQPNVTHKWLKNMEDI-GKVSCVITQNVDNLHIKAGSKNVVELHGTGYRVVCLSCNNKIDRFPDVFKIPPCSKCG--GIMKPDIVFFGDNVPVVERV
QNEVEEADSLLVLGTSLTTFSGYRIVLQAVEAVKPIAILNIGDTRGDEHAQIRVHGRCGEILPMLTD------------
>tr|W2WNF3|W2WNF3_PHYPR Uncharacterized protein OS=Phytophthora parasitica CJ01A1 GN=F441_12501 PE=4 SV=1
------------------------KTLDSIADFVKVLKKAKKVVVIAGAGISVSCGIPDFRSKDGIYAMPEPECLFQIDYFRDDPAPFFEVVRNA---FA
-NSPKPSPTHWFLKLLQDK-KKLLRVYTQNIDGLEEAAGVTRCIPCHGSFAYSACMRCKKRVPTSTLMGIIPSCSECR--GVLKPEITFFGEILDKVSTM
TKDRLQADLLLVMGTSLKVAPVMEIPGYLPS-HIPQVVINKTALKKEEEFDMSLLGDCDDIIRYICAQAGWDL------
>tr|A0A024TGS5|A0A024TGS5_9STRA Uncharacterized protein OS=Aphanomyces invadans GN=H310_13210 PE=4 SV=1
------------------------PRLESLDDAVQALKKAKHIVVVVGAGISVSCGIPDFRSKDGIYALPDAESLFDMDFFRSNPMPFFRFAAAF---FK
-DSFTPSPTHRFLRRLHDQ-NQLLRVYSQNVDGLEAAAGVTNVIQCHGTLATSSCMSCDYTVDTSAALGVIPRCPHIH--GILKPNITFFGETLQATRHA
PLDRNKADLVLVMGTSLQVSPVADIPVYLNA--VPQILVNMQSVRPHRGFDVECLGPSDAIVEYLITAMDGRV------
>tr|A0A0R3UGL0|A0A0R3UGL0_9CEST Uncharacterized protein OS=Mesocestoides corti PE=4 SV=1
-----------------------------------ADGKARQIVVMAGAGISTASGIPDFRSPTGLYANLYPEAIFDINFFKRRPSA---FYALAKELYP
TGKYRPNIAHYFFRLLYQK-RILRRVYTQNIDGLERVAGVSKLVEAHGTFATARCLQCGRPVPARIDHGKVARCFRCK--GLVKPDVVFFDEALPKFWRY
REDIPKSDLIFVMGTSLETQPFSKLVAASR-PNTPRILLNKHPVGPFKPNDLVALGDISCLIRELCTLL----------
>tr|W6UJD1|W6UJD1_ECHGR NAD-dependent deacetylase sirtuin-3 OS=Echinococcus granulosus GN=EGR_03429 PE=4 SV=1
-----------------------------------SEGKAHDIIVMAGAGISTASGIPDFRSPTGLYANLYPEAIFDINYFKIRPSA---FYALAKELYP
TGKYRPNIAHYFFRLLNQK-RLLRRVYTQNIDGLERVAGISKLVEAHGTFATAQCLKCEKSIPARIDRGKVARCYRCR--GLVKPDIVFYNEDLPKFWRY
REDIPKGDLIIVMGTSLEVQPFSKLIVATH-SNTPRVLFNKHIVGPFRPKDFVALGDISTLIRELCALL----------
>tr|H2TFY2|H2TFY2_TAKRU Uncharacterized protein (Fragment) OS=Takifugu rubripes GN=LOC101066119 PE=4 SV=1
----------------------------------VKLGRCKNVVVVAGAGISTASGIPDFRTPTGLYANYYPEAVFNIDFFSNDPLP---FFSLAKALY-
PGSHRPNYIHYFIRVLHHK-GLLLRMYTQNIDGLEKLCGIDKLVEAHGSFSTASCHLCYTAFPAAEAKDKVPLCSFCA--ATVKPDVVFFGEDLPKYFLH
TKDFPKADLLIIMGTSLQIEPFASLVNTVRS-TVPRLLLNRHAVGFERRGDHMELGDLVATVRRFAEML----------
>tr|M3ZHI5|M3ZHI5_XIPMA Uncharacterized protein OS=Xiphophorus maculatus PE=4 SV=1
----------------------------------VKLGRCKNILVVVGAGISTPSGIPDFRTPTGLYANYYPEAIFNIDYFSNDPQP---FFSLAKALY-
PGCHRPNYIHYFIRMLHHK-GLLLRLYTQNIDGLENVCGIDKLVEAHGSFATASCHLCYTPYPAEEAKDNIPTCSFCA--ATVKPDVVFFGEDLPKYFLH
TKDFPKADLLIIMGTSLKIEPFASLVNTVRS-TVPRLLLNRHAVGFERRGDHMELGDLADSVRRFAEIL----------
>tr|W5NDS6|W5NDS6_LEPOC Uncharacterized protein OS=Lepisosteus oculatus PE=4 SV=1
----------------------------------IQQRPCRNIIVVAGAGISTASGIPDFRTPSGLYANYYPEAIFDIDYFTCDPQP---FFSLAKELY-
PGCYRPNYVHYFVRMLHEK-GLLLRMYTQNIDGLERISGIEKLVEAHGTFSSASCHLCYTKFPVTEAKNKVPRCKNCQ--GTVKPDVVFFGEDLPKFFLH
TKDFPKADLLIIMGTSLQIEPFASIVNTVKA-TVPRLLLNRDPIGFQKRTDFMELGDLVDGVKMFARHL----------
>tr|I2JQS1|I2JQS1_DEKBR Putative sir2 family histone deacetylase OS=Brettanomyces bruxellensis AWRI1499 GN=AWRI1499_4809 PE=4 SV=1
------------------------------NDVCNALQKAXHILVLTGAGISTSLGIPDFRSSTGFYSRDDPQDVFSVDLFRQDPSI---FYSIAHLIL-
PPDKACTPLHAFIKLLQDK-GKLLRNYTQNIDNLEANAGVENLVQCHGSFATASCFTCNYKVPGEVLAQEIAYCPFCAVFGVMKPDITFFGEDLPRYNFI
KEDVKKCDLLLCIGTSLKVAPVSEIVNKVPN-DVPQILINRDPIDH-CEFDVELLGYCDQAITWLCNE-----------
>tr|C4QWX8|C4QWX8_PICPG Conserved NAD+ dependent histone deacetylase of the Sirtuin family OS=Komagataella pastoris (strain GS115 / ATCC 20864) GN=PAS_
------------------------------DHLIEAIKTSKNILVLTGAGISTSLGIPDFRSSEGFYTKDDPQTVFDLEYFKQDPSL---FYSIAHLVL-
PPEGSFTPLHGFIKLLADK-GSLLRNYTQNIDNLEANAGIEKVIQCHGSFATASCITCKYKIPGETINSELPLCPFCIKYGVMKPDITFFGEDLPVFDNI
IQDVKNCDLLLCIGTSLKVAPVSEIVNKVKP-EIPQVLINKDPVTH-TEFDISLLGYCDELIVYLCEA-----------
>tr|W1QHL6|W1QHL6_OGAPD NAD-dependent histone deacetylase SIR2 OS=Ogataea parapolymorpha (strain DL-1 / ATCC 26012 / NRRL Y-7560) GN=HPODL_00539 PE=4 S
------------------------------EHVKNALENAKNVLVLTGAGISTSLGIPDFRSSQGFYARDDPQDVFSLEVFKRSPEV---FYSIAHMIL-
PPEAAYTPLHGFIRLLQDK-GKLLRNYTQNIDNLEANAGVEKIVQCHGSFATASCITCKYKVPGETLRQEIAYCPFCENFGVMKPDITFFGEDLPQFTTI
KSDIEKCDLLICIGTSLKVAPVSEIVNLVPN-HVPQILINKDPIYH-CEFDVDILGYCDHVITYLTGK-----------
>tr|A0A099NYY9|A0A099NYY9_PICKU Uncharacterized protein OS=Pichia kudriavzevii GN=JL09_g3779 PE=4 SV=1
------------------------------KHVVDALSKAENIIILTGAGISTSLGIPDFRSSQGFYSKDDPQEVFSLDVFRRDPSI---FYSIAYMIL-
PPEDSSTPLHAFIKLLQDK-GKLLRNYTQNIDNLEGNVGVEKLVQCHGSFATASCITCKYNIPGETLSKKIAYCPFCESFGVMKPDITFFGENLPRYDTI
KEDIEKCDLLITIGTSLKVAPVSEIVNRIPA-HVPQILINRDPINH-CEFDVEFLGYCDQAITWICGK-----------
>tr|V3ZQZ0|V3ZQZ0_LOTGI Uncharacterized protein (Fragment) OS=Lottia gigantea GN=LOTGIDRAFT_196160 PE=4 SV=1
------------------------------YQLAEKIKSCKNIVVYTGAGISTAASIPDYRGPNGIWTLLKKGQEPR------------------AQDLS
--DAEPTFTHMSITKLQQQ-GHISYVVSQNCDGLHLRSGFNALSEVHGNMYLETCYSCKPEYVRLFDVTTGRTCHKCG--GMLKDTIVHFGEKPYHWKKA
AKAANNADMILCLGTSLKVLPCLWAMDKRPSQRPTLCIVNLQWTPKDDNSALKINGRCDEVFDRVMKFLNLS-------
>tr|G3GXB6|G3GXB6_CRIGR NAD-dependent deacetylase sirtuin-7 OS=Cricetulus griseus GN=I79_002406 PE=4 SV=1
--------------------------------MDIA-SERKKCEVSISQHLIRGSSCPCLTQPFYLFSLLS-----CS-----------------AADLS
--EAEPTLTHMSITRLHEQ-KLVQHVVSQNCDGLHLRSGLTAISELHGNMYIEVCTSCVPEYVRVFDVTTGRTCHKCG--TQLRDTIVHFGERPLNWEAA
TEAASKADTILCLGSSLKVLPRLWCMTKPPSRRPKLYIVNLQWTPKDDWAALKLHGKCDDVMQLLMDELGLE-------
>tr|M3W8F1|M3W8F1_FELCA Uncharacterized protein (Fragment) OS=Felis catus GN=SIRT7 PE=4 SV=1
------------------------------PEEAGVLGSRREELDRVGAGVRAAASIPDYRGPNGVWTLLQKGRSVS------------------AADLS
--EAEPTLTHMSIARLHEQ-KLVQHVVSQNCDGLHLRSGLTAISELHGNMYIEVCTACTPEYVRVFDVTTGRACHKCG--AQLRDTIVHFGERPLNWEAA
TEAASKADTILCLGSSLKVLPRLWCMTKPPSRRPKLYIVNLQWTPKDDWAALKLHGKCDDVMQLLMDELGLE-------
>tr|A0A0A9YPJ5|A0A0A9YPJ5_LYGHE NAD-dependent deacetylase sirtuin-7 (Fragment) OS=Lygus hesperus GN=SIRT7_0 PE=4 SV=1
------------------------------MKLASAISSSQYMVVYSGAGVSTAASIPDYRGSNGIWTRLQQGKDIG------------------EHDLS
--VAEPTTAHMAIYRLYRQ-GMVKHVVSQNCDGLHLRSGLRALSEVHGNMNLEVCTKCNL-VWRNFDVTTARRCTQCC--EPLRDTIVHFGERPINWNGA
CAAAKQADMILCIGSSLKVLPWLWGMDKPVKKRPQLYIVNLQWTPKDDQATVKINGKCDEVMKLVMSYLKLD-------
>tr|H2XLI8|H2XLI8_CIOIN Uncharacterized protein OS=Ciona intestinalis GN=LOC100185848 PE=4 SV=1
------------------------------IDLAKALQTAKHAVVYTGAGISTAANIPDYRGTNGVWTRLKSGKDVNS-----------------CQNLV
--SAVPTFTHMCIEALVRH-HIVQHVVSQNCDGLHVRSGVDKLSELHGNMFCEICPNCDA-YYRLFDVTTGRTCDKCN--EGLKDTIVHFGERPHNWESA
ESNAYDADLILCLGSSLKVLKQLWLTERTKRNRPKLYIVNLQWTPKDSQATSKINGSVDEVMKIVMLYLSIV-------
>tr|F7D2Y2|F7D2Y2_XENTR Uncharacterized protein (Fragment) OS=Xenopus tropicalis GN=sirt7 PE=4 SV=1
------------------------------LQLAGAFRAAEHVVIYTGAGISTAAAIPDYRGPSGVWTLLNKGRTVN------------------AGDLS
--EAQPTFTHMCIVRLHSA-GLVQHIVSQNCDGLHLRSGLEAISEVHGNMFIEVCTLCSPEYVRLFDVTTGRFCHNCG--AELRDSIVHFGERPLNWEGA
VQASEKADVILCLGSSLKVLSCLWGMNRARARRPKLYIVNLQWTPKDSVATLKINGKCDDVMQILMEELNLN-------
>tr|Q5ZJG7|Q5ZJG7_CHICK Uncharacterized protein OS=Gallus gallus GN=RCJMB04_18f9 PE=2 SV=1
------------------------------VELAAAIRNAKHLVIYTGAGISTAASIPDYRGPNGIWTLLQKGRSIS------------------TTDLS
--EAEPTLTHMSIACLHKH-NLVQHVVSQNCDGLHLRSGLSAISELHGNMYIEVCTSCTPEYVRVFDVTTGRMCHKCG--AQLRDTIVHFGEKPLNWEAA
TEAASKADVILCLGSSLKVLPRLWCMSKPPPRRPKLYIVNLQWTPKDDLAALKLHGRCDDVMRLLMEELGLQ-------
>tr|A7T2R8|A7T2R8_NEMVE Predicted protein OS=Nematostella vectensis GN=v1g176429 PE=4 SV=1
------------------------------CQLVGAIREAKTLAIYTGAGISTAARIPDYRGPNGIWTRLAKGERLG------------------SYNLC
--DAEPTLSHMSITKLYQE-GLVRHVVSQNCDGLHIRSGLQALSEVHGNMFTEVCTECEDIYYRLFDVTTGRFCTDCG--SPLRDTIVHFGEKPLNWQAA
FDVAKIADCILCLGSSLKVLHALWGMNRVKHRRPKLFIVNLQWTPKDESASLKIHARCDNVMKRVMEKLGLE-------
>tr|H0UX59|H0UX59_CAVPO Uncharacterized protein OS=Cavia porcellus GN=SIRT7 PE=4 SV=1
------------------------------RELASAVRSAKYLVVYTGAGI-SAASIPDYRGPNGVWTLLQKGRSVSS-----------------AADLS
--EAEPTLTHMSIMHLHEQ-KLVQHVVSQNCDGLHLRSGLTAISELHGNMYIEVCTSCIPEYVRVFDVTTGRTCHKCG--AQLRDTIVHFGERPLNWEAA
TEAASKADTILCLGSSLKVLPRLWCMTKPPSRRPKLYIVNLQWTPKDDWAALKLHGKCDDVMRLLMGELGLE-------
>tr|V8P8X9|V8P8X9_OPHHA NAD-dependent deacetylase sirtuin-7 (Fragment) OS=Ophiophagus hannah GN=SIRT7 PE=4 SV=1
------------------------------SKLSAVVQGAKHLIVYTGAGISTAASIPDYRGPNGVWTMLQKGRSIR------------------ATDLS
--EAEPTLTHMSIACLHNN-KLVKHVVSQNCDGLHLRSGLEALSELHGNMYIEVCTSCTPEYVRIFDVTTGRLCHKCG--AQLRDTIVHFGEKPLNWEAA
TEAASKADVILCLGSSLKVLPHLWCMSKPPRHRPKLYIVNLQWTPKDDLAVLKLHGRCDDVMKLLMDELGLP-------
>tr|E4WSC2|E4WSC2_OIKDI Uncharacterized protein OS=Oikopleura dioica GN=GSOID_T00000658001 PE=4 SV=1
------------------------------AKLIEMIREAQHPIVYTGAGISTSANIPDYRGTGGVYSAMAAGQDIK------------------QCNLV
--TATPTLGHMALSGLIKN-KIFKFLLSQNCDGLHLRSGIEQLSEIHGNMFMENCDEG--FFYRAFDVTTGRACSDCE--EDLYDAIVHFGEMPYRWETA
ETHSSKTDLIICIGTSLKVLKVLWP------KKCKLVIINLQWTPKDKHADLLIRGQSDQILCEVAKAFDVA-------
>tr|G3W881|G3W881_SARHA Uncharacterized protein OS=Sarcophilus harrisii GN=SIRT7 PE=4 SV=1
------------------------------RELALAVQNAKYLVIYTGAGISTIAKLSDILGERKMKIMLRIGRGER------------------GVHES
--SMKPFLTFLLFLKLGKV-RLIFNTVIRGFTALHLPS--NSLRALGGNHFSPVCTSCTPEYLRVFDVTTGRTCHKCG--AQLRDTIVHFGERPLNWEAA
TEAASKADTILCLGSSLKVLPRLWCMTKPPSRRPKLYIVNLQWTPKDDLAALKLHGKCDDVMQLLMDELGLE-------
>tr|B7Q994|B7Q994_IXOSC Chromatin regulatory protein sir2, putative OS=Ixodes scapularis GN=IscW_ISCW021135 PE=4 SV=1
------------------------------RALAGAIGAARRLVVYTGAGISTAARIPDYRGPEGVWTLLQKGMVPQ------------------VQDLS
--RARPTFTHMAIAQLQQA-GLVKHVVSQNCDGLHVRSGLTCLSELHGNMFLEVCPSCKPQYFRLFDVTTGRKCHGCS--SELVDTIVHFGETPLNWQGA
GKAADRCDAILCLGTTFVVLRCLWAMDRPARERPKLYIVNLQWTPKDDIAALKVNGRCDEVMQAVMGFLNIR-------
>tr|I3KMP4|I3KMP4_ORENI Uncharacterized protein OS=Oreochromis niloticus GN=LOC100700228 PE=4 SV=1
------------------------------RQLAVAVKQASHLVVYTGAGISTAASIPDYRGPNGVWTQLQKGRAI-S-----------------SSDLS
--KAEPTLTHMCIKMLHKE-KLVKHVVSQNCDGLHLRSSLHALSELHGNMFIEVCTSCSPEYVRLFDVTTGRKCSHCG--SELRDTIVHFGERPLNWRGA
TEAAKMADVILCLGSSLKVLTNLWCMNRPASKRPKLYIVNLQWTPKDDLAVLKIHGKCDDVMRLLMEELNLQ-------
>tr|W5U8J4|W5U8J4_ICTPU NAD-dependent protein deacetylase sirtuin-7 OS=Ictalurus punctatus GN=SIRT7 PE=2 SV=1
------------------------------KQLAEAMRQARHVVVYTGAGISTAASIPDYRGPNGVWTQLQKGRAV-R-----------------HSDLS
--EAEPTLTHMCIQMLHKV-KVVQHVVSQNCDGLHLRSGLHALSELHGNMFIEVCVSCSPEVIRLFDVTTGRRCAHCR--GELRDTIVHFGERPLNWKGA
AAAAEQADLILCLGSSLKVLACLWCMKKTAAKRPKLYIVNLQWTPKDDLATLKIHGKCDDVMRLLMEELGVE-------
>tr|F1Q4W1|F1Q4W1_DANRE Uncharacterized protein OS=Danio rerio GN=sirt7 PE=4 SV=1
------------------------------KQLAEAVQRAKHLVIYTGAGISTAASIPDYRGPNGVWTQLQKGRSV-S-----------------TSDLS
--QAEPTLTHMSIWMLHKM-KMVQHVVSQNCDGLHLRSGLHALSELHGNMFIEVCDSCSPEFIRLFDVTTGRSCPHCR--AELRDTIVHFGERPLNWKGA
AEAAQRADLILCLGSSLKVLSCLWCMNRPASKRPKLYIVNLQWTPKDNLATLKIHGKCDAVMALLMEELALA-------
>tr|H2M9M7|H2M9M7_ORYLA Uncharacterized protein OS=Oryzias latipes GN=sirt7 PE=4 SV=1
------------------------------QQLAAAVRQASHLVVYTGAGISTAASIPDYRGPNGVWTQLQRGQAV-S-----------------SSDLS
--QAEPTLTHMCIRMLHEE-KLVKHVVSQNCDGLHLRSGLHALSELHGNMFIEVCTSCSPEYVRLFDVTTGRSCSCCG--AELRDTIVHFGERPLNWEGA
VEAARRADVILCLGSSLKVLSCLWSMNRPVNKRPKLYIVNLQWTPKDDLAVLKIHGRCDDVMRRLMEELNLQ-------
>tr|G3Q5K8|G3Q5K8_GASAC Uncharacterized protein OS=Gasterosteus aculeatus PE=4 SV=1
------------------------------KQLAAAVEQAKHLVVYTGAGISTAASIPDYRGPNGVWTQLQKGRTIRN----------------SSSDLS
--KAEPTLTHMCIRMLHKE-NLVRHVVSQNCDGLHLRSGLHALSELHGNMFIEVCTSCSPEYVRLFDVTTGRRCSHCG--GELSDTIVHFGERPLNWKGA
SEAAEKADVILCLGSSLKVLPCLWCMNRPGSKRPKLYIVNLQWTPKDDLAVLKIHGKCDDVMSLLMEALNIQ-------
>tr|M4AEU3|M4AEU3_XIPMA Uncharacterized protein OS=Xiphophorus maculatus PE=4 SV=1
------------------------------KQLAAAVKQANHLVVYTGAGISTAASIPDYRGPNGVWTQLQKGRTV-S-----------------SSDLS
--KAAPTVTHMCIRMLHKE-KLLKHVVSQNCDGLHLRSGLQALSELHGNMFIEVCTSCSPEFVRLFDVTTGRRCSHCG--SELRDTIVHFGERPLNWKGA
AEAANEADVILCLGSSLKVLACLWSMSRPANKRPKLYIVNLQWTPKDDLAVLKIHGKCDDVMRLLMEELNIQ-------
>tr|W5KHN0|W5KHN0_ASTMX Uncharacterized protein OS=Astyanax mexicanus PE=4 SV=1
------------------------------KQLAEAMRQAQHAVIYTGAGISTAASIPDYRGPNGVWTQLQKGRTV-M-----------------ASDLS
--DADPTLTHMCIRMLHKI-KMVQHVVSQNCDGLHLRSGLPALSELHGNMFIEVCVSCSPEIIRLFDVTTGRRCPHCG--AELKDTIVHFGERPLNWKGA
AEAAEQADLILCLGSSLKVLACLWSMKKPAAKRPKLYIVNLQWTPKDDLATLKINGKCDDVMRLLMEELCTE-------
>tr|A0A0P7UED5|A0A0P7UED5_9TELE NAD-dependent protein deacetylase sirtuin-7-like (Fragment) OS=Scleropages formosus GN=Z043_115341 PE=4 SV=1
------------------------------SQLAAAVRGARHLVVYTGAGISTAASIPDYRGPNGLWTQLQKGRSV-S-----------------TSDLS
--AAEPTLTHMSIRMLHKE-KLVQHVVSQNCDGLHLRSGLHALSELHGNMFMEVCTSCSPEYVRLFDVTTSRRCPQCG--GELRDTIVHFGERPLNWKGA
MEAAAKADVILCLGSSLKVLTCLWCMNKSTDKRPKLYIVNLQWTPKDDLATLKIHAKCDDAMRLLMQELDIT-------
>tr|B3RPH8|B3RPH8_TRIAD Putative uncharacterized protein OS=Trichoplax adhaerens GN=TRIADDRAFT_53549 PE=4 SV=1
------------------------------DQLAEAVRCAKCLVIYTGAGISTAAQIPDYRGPNGVWTQLARGRRAT------------------GRDMI
--EAEPTFTHMAIVELYKA-NLANYVVSQNCDGLHLRSGLSALSEVHGNMYMEVCSNCQPEYFRLFDVTTRRTCDVCG--NNLVDTIVHFGERPHNWQTA
IDWANKTDMILCLGSSLKVLHPLWGSKRAKSKRPKIFIVNLQWTPKDSYSTLKINAPCDIVMKSLMRKLDIC-------
>tr|W5N4B7|W5N4B7_LEPOC Uncharacterized protein OS=Lepisosteus oculatus PE=4 SV=1
------------------------------KELAAAVRAATYLVVYTGAGISTAASIPDYRGPNGVWTLLQKGRSV-S-----------------ASDLS
--EAEPTLTHMCIGKLHEE-KLVQHVVSQNCDGLHLRSGLQALSELHGNMYIEVCTACSPECVRLFDVTTGRHCSRCG--AELRDTIVHFGERPLNWKGA
AEAAAKADAILCLGSSLKVLACLWCMNRTPNKRPKLYIVNLQWTPKDDLAALKIHGKCDDVMKLLMEELDIQ-------
>tr|V9KUD3|V9KUD3_CALMI NAD-dependent deacetylase sirtuin-7 OS=Callorhinchus milii PE=2 SV=1
------------------------------KLLVTAVQEARYLVIYSGAGISTAASIPDYRGPNGVWTSLQSGRAVS------------------ATDLS
--EAEPTLTHMCIAQLYKE-KLVQHVVSQNCDGLHLRSSLKALSELHGNMYIEVCTYCTPEYVRLFDVTTGRRCHKCA--NEMRDTIVHFGEKPLNWKGA
AEAAKKADVIICLGSSLKVLPCLWCMNRAPHKRPKLYIVNLQWTPKDDFATLKIHAKCDDVMKLIMEEQGIE-------
>tr|H3AKL9|H3AKL9_LATCH Uncharacterized protein OS=Latimeria chalumnae GN=LOC102361134 PE=4 SV=1
------------------------------MRLAWAIREAKRVVMYTGAGISTAASIPDYRGPNGVWTLLQKGRALS------------------QAELS
--EADPTFTHMCIMKLQQE-QLVHHVVSQNCDGLHLRSGLHALSELHGNMYIEVCTSCSPEYVRLFDVTTGRKCHSCR--GDLRDTIVHFGERPLNWKGA
AAAAEEADAILCLGSSLKVLACLWGMNKQPHRRPKLYIVNLQWTPKDDQAALKIHGKCDDVMTLLMEELGLK-------
>tr|A9V9J9|A9V9J9_MONBE Predicted protein OS=Monosiga brevicollis GN=28831 PE=4 SV=1
------------------------------TKVATLLQQARTAVVYTGAGLSTASGIPCYRGQHGIYTKTAKNSTADTTVAP--------TPAPTTLDLT
--ACSPTRAHQALTALVQG-GVVQHVVSQNVDGLHRRSGLQHLSEIHGNAFLEYCPVCSNLYARRFDVTTGRNCPACA--TPLLDTIVHYGEAVHNWEGI
EALLPQVDLILVLGSSLKVLKPLWQ---PLQKKASLIVVNLQWTPLDARAALVVRATCDAFLEALLNALPPA-------
>tr|H2XW94|H2XW94_CIOIN Uncharacterized protein OS=Ciona intestinalis GN=sir2-a PE=4 SV=1
------------------------------KDVAELISGVRNIIVMAGAGISTGSGIPDFRTPTGLYDNLAPTAVFDRDYFNVNPKP---FFELAKELYP
SGKYRPNIVHYFVRCLHEK-GLLLRMYTQNIDGLERLAGISKLVEAHGTFSTASCTKCGKKCKGEDKILVIPRCPLCY--GTIKPDIVFFGEDLKRFYYY
LKDFPSCDLLLVFGTSLQVEPFASLVDSARF-TTPRLLLNMVKVGFGRRHDLAVTGDIMDSIQTFVDEL----------
>tr|H3AAK4|H3AAK4_LATCH Uncharacterized protein OS=Latimeria chalumnae GN=SIRT3 PE=4 SV=1
------------------------------EDIARKIRECNRIVVMAGAGISTPSGIPDFRSPSGLYDNLYPEAVFEINYFLHDPKP---FYSLAKELYP
-GNYKPNWAHYFVRLLYKK-GMLLRMYTQNIDGLERLAGISMLVEAHGSFATASCTVCCESYPGEDEVMKVPLCPICT--GVIKPDIIFFGQELKRFFLY
LTDFPLADLLIIMGTSLEVEPFASLAGAVRS-SVTRLLINRDLVGFSRSNDVVELGEVIGGVRKFVDLL----------
>tr|A0A0P7AQ21|A0A0P7AQ21_9HYPO NAD-dependent protein deacetylase hst2-1 OS=Neonectria ditissima GN=AK830_g10409 PE=4 SV=1
-------------------------------------GAVKRIVVLTGAGISTAAGIPDFRSETGLYNNLYAEAVFDIGYFRQHPEP---FYVLAKELY-
PGTFQPTVSHAFIALLARK-GLLQMLFTQNIDCLERAAGVEKIIEAHGSFASQRCIECKTEFPDDKIVGEVPHCGECN--GLVKPDIVFFGESLPAFNSN
TYQATMADLMLIIGTSLTVYPFAGLPEMAM-QGKPRVLFNMEQVGQGRRADVIELGSCDAGIRKLADELG---------
>tr|J4KN88|J4KN88_BEAB2 Sir2 family protein OS=Beauveria bassiana (strain ARSEF 2860) GN=BBA_05610 PE=4 SV=1
-------------------------------------GDVKRIVVMTGAGISTAAGIPDFRSPTGLYNNLHAEAVFEISYFKENPEP---FYVLAKELY-
PGKFHPTVSHVFLSLLAQK-GLLHMLFTQNIDCLERAAGVEKIIEAHGSFATQRCVECKKEFPDDEMVGDVPRCIDCN--GLVKPDIVFFGEALPAFSEQ
SHKAAMADLALIIGTSLQVYPFAGLPQMVR-ESIPRVLFNMEKVGQGTRADVVSLGPCDDGVRQLAAELG---------
>tr|F4WPE5|F4WPE5_ACREC NAD-dependent ADP-ribosyltransferase sirtuin-4 OS=Acromyrmex echinatior GN=G5I_07622 PE=4 SV=1
-------------------------------------DRHHHLCVLTGAGISTESGIPDYRSAEGLYARSNRKP-ILYKEFCDSEAIRKRYWA--RNYIG
WPSLKPNITHEILKHLEYI-GKVGCIVTQNVDNLHLKAGSKKVIELHGTAFRVMCLNCDHKISRHEDVFNVPACDNCS--GILKPDIVFFGDNVEKVQNV
KDNVENLDALLILGTTLSTFSAYRIVLQAIDAKKPIAIVNIGETRADKCINLKVEGRCGDILPKIWQLN----------
>tr|A0A074ZU15|A0A074ZU15_9TREM Uncharacterized protein OS=Opisthorchis viverrini GN=T265_05947 PE=4 SV=1
------------------------------DQLVEHISRSRHMLVLTGAGVSTESGLPDYRSEVGLYARTDRR-PVEFQTFLRNEEAR-RFYWA-RNFIG
WPQVQPNTSHHILADWASK-NWLFAIITQNVDRLHHLAGCNRILELHGTSHYVVCLNCQHRFGRAEDVFKIPTCPQCGD-GILKPDVVFFGENLWRKTEA
AQLVDNADSLLCLGTSLQVGSSYRLILQACERKLPVSIVNIGPTRADSLVQLRLYSRISTTL-----------------
>tr|D8LES8|D8LES8_ECTSI Similar to sirtuin OS=Ectocarpus siliculosus GN=Esi_0014_0023 PE=4 SV=1
----------------------------SLEKLVNLLRTCKRVVVVTGAGISVSCGIPDFRSEHGVYDLSSAEDLFDLEFFVDDPEPFFKFAKVL----Y
PGNYVPSLTHRFIKALENR-GKLLRNFTQNIDGLEAQVGLKKYVACHGSFLTASCLKCKRKRTAREEVQRVPRCPSCQ--GVVKPDITFFGERLPSVKRA
VEDHKKADLFLVLGTSLKVQPVSRILQFIPP-HVPQVLVNRELIRISDGFDLHLLGDCDDVIQHLYT------------
>tr|A0A0L0SFJ7|A0A0L0SFJ7_ALLMA Uncharacterized protein OS=Allomyces macrogynus ATCC 38327 GN=AMAG_07014 PE=4 SV=1
------IAVQRFI--RRRQRLPNVSTL---GHAVELLQKSSRIMVVTGAGISVSCGIPDFRSKNGIYSREDPTQMFDLEYFRRKPETFYSFANEI---Y-
PSNFKPSPCHAFVALLEQQ-GKLLRNYTQNIDNIEQLAGIERVIQCHGSFRTARCVTCGYKVPGNAEAKTVPKCPKCPPFPVIKPDIVFFGEQLPEFDQI
KPDLAATDLILVIGSSLKVAPVSEILSSVPD-HVPQLIINRELLPLAHHFDVHLLGNADTVVMELCRRA----------
>tr|Q6MFN0|Q6MFN0_NEUCS Related to NAD-dependent histone deacetylase OS=Neurospora crassa GN=B8I24.120 PE=4 SV=1
--------------IQKRAKLMKYNTI---DDAVELLKRSKNIIVLTGAGISTSLGIPDFRSKTGLYSKSDPQEVFDINIFRQDPNI---FYSVARDILP
-NTERFSPTHAFIALLQQK-GKLLTNYSQNIDNLEAKAGIDKLVQCHGSFATATCVKCGYKVPGESEIGRIPRCRKCAQCGVMKPDITFFGEALPEFTRL
THDRDLVDLVIVIGTSLKVAPVSEVVPFLPP-HIPQIYISRTPVSH-VNFDIDLLGDCDVVVSELCKRAGWDLQH----
>tr|A0A0G2FLK9|A0A0G2FLK9_9PEZI Putative sir2-like protein OS=Diaporthe ampelina GN=UCDDA912_g05101 PE=4 SV=1
--------------LSKRAKLQQYNSV---DDAVALLKKSKNIIVLTGAGISTSLGIPDFRSKTGLYSKNDPQEVFDISLFKQDPSI---FFSVARDIMV
-ETERFSPTHAFIALLQKH-GKLLTNYSQNIDNLESKAGIDKLIQCHGSFATATCFTCYHQVPGDDDIGKIPRCPKCGIGGIMKPDITFFGEALPEFSRL
VHDRDKTDLVVVIGTSLKVAPVSELVPFLYP-HIPQIYISRTPVNH-HNFDIDLLGDCDVVVAELCRRAGWDLRH----
>tr|B2AR57|B2AR57_PODAN NAD-dependent histone deacetylase Pasir2 OS=Podospora anserina (strain S / ATCC MYA-4624 / DSM 980 / FGSC 10383) GN=PODANS_4_85
--------------LKKRAKLTRYNTV---DDAVALLKEKKNIIVLTGAGISTSLGIPDFRSATGLYSKNDPQEVFDLSVFRQDPTI---FYSVAKDILP
-SEDRYTPTHQFIRMLQER-GKLLTNYTQNIDNLESKAGIEKLVQCHGSFATASCVKCGEKVVGDSEIGKIPRCRKCPSAGVMKPDIIFFGEPLPEFQRL
THDVDRVDLVIVIGTSLKVAPVSEVVPYLPS-HIPQIYISREAIGH-NNFDIDLLGDCDVVVAELCRRAGWELGH----
>tr|A0A0H5R9Z1|A0A0H5R9Z1_9EUKA Uncharacterized protein (Fragment) OS=Spongospora subterranea PE=4 SV=1
--------------------------------AAIASGRLRKVIILCGAGISVSAGIPDFRSPTGLYYRPRPEAVFDITYFRKRPEPFYTLASELWPGS-
-GKFVPTIGHHVLRLLADK-GIVHRIYTQNIDGLERLAGIDLLVEAHGTFSAASCIDCKSPYPVDRIIFEVPYCSLCG--GLVKPNVVFFGEQLPRRETI
YEDLSECDLLLVIGTSLTVQPFASLVDMVPD-SCFRVLINRDLVGVHHSNDVFWQGDCDDGLTLLAQ------------
>tr|D2VAB4|D2VAB4_NAEGR Silent information regulator family protein OS=Naegleria gruberi GN=NAEGRDRAFT_65800 PE=4 SV=1
--------LQCFTD----------SNNNSNSKDIQELIDDHSIVVLTGAGLSTASGIPDFRTPKGLFVNPDPMAIFDSDYFQTNPEPFFE---LTRD--F
TTGYKPSKAHYFLKLLEKK-NKLLRLYTQNIDGLETKSGIELLVNCHGMYDTAKCQHCKKEYLLPTV-VKIPKCDDCGN--VIKPDIVMYSDDLPE--KY
KDDLTTPKCFICIGTSLSVMPVCRMPYFIINREG--VFTHIKSPVREKHLDLFLGGKTMTI------------------
>tr|Q6FU79|Q6FU79_CANGA Uncharacterized protein OS=Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) GN=CAGL0F05621g PE=
--------FAR-GKSGRKPRLKSRPAPFTIDDAAYAFQYSKKIVAVVGAGISVAAGIPDFRSSEGLFETASGKELFDFNRVYSSDEMSKKFHSMIVDLHS
SQKSEPTKFHLLLDHLASQ-QRLVRLYTQNIDGLDTRLENPTTIQLHGSVDYMECNLCAKIDCFNPEGEIIPLCPQCKELGKLRPRVVLYNEVHPEGDLI
NKDLQKIDFLLIAGTSLKIPGVLQMCKKFVKNKGIVIYFNKEMPTQKGHIDLIVLGDCQNI------------------
>tr|A0A0D4LLH4|A0A0D4LLH4_YEASX Hst4p OS=Saccharomyces cerevisiae YJM320 GN=HST4 PE=4 SV=1
--------LPQLKKRNRKPRLSYRPELNSLDADAYALNYSKRMVVVSGAGISVAAGIPDFRSSEGIFSTGSGKDLFDYNRVYGDESMSLKFNQLMVSLFR
SKNCQPTKFHEMLNEFARD-GRLLRLYTQNIDGLDTQLPHPSTVQLHGSIKHMECNKCLNIKPFDPETEIIPSCPQCEEVGKLRPRVILYNEVHPEGDFI
NNDLKRIDCLIIVGTSLKIPGVKNICRQFHANRGIVLYLNTSMPPKDKFVDLVVLGDCQHV------------------
>tr|A7TMS1|A7TMS1_VANPO Putative uncharacterized protein OS=Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294) GN=Kpol_1030p1 PE=4 SV=1
--------LTQLKKNTRKPRLKFRPAPFTIDDNIYALKHSRRVIVGTGAGVSVAAGIPDFRSSQGLFTSSSGKELFDYNRVYSSDNMSIKFNEMIKKLHK
SSSTEPTAFHELINSIALD-GRLQRLYTQNIDGLDVRLPHPKTIQLHGSIHYMECNKCSKIEEIDTSTQIVPSCKQCLEVGRLRPRVVLYNEVHPEGDLI
NLDIKKPDCLIIAGTSLTIPGVKSLCKQFRDSKGIVIYMNKEMPSKDGNIDLIVLGDCQKA------------------
>tr|H2ARB2|H2ARB2_KAZAF Uncharacterized protein OS=Kazachstania africana (strain ATCC 22294 / BCRC 22015 / CBS 2517 / CECT 1963 / NBRC 1671 / NRRL Y-82
--------FRSVSS-----KSKYRPKPNTL--NLHVLQNSQQMVMITGAGISTHAGIQDFRSQNGLYRTTSMKSLFDYNQVYSNEQTTANFNKLMVDIYE
SNNADPTPFHLLIDKINRQ-GRLRRVYTQNIDSIEWKLLSSKLVQLHGTILKTKCNKCQKIEDFETQLPLIPNCKQCEEVGKIRPMITLYNEPYHESDTL
NHDLYKIDCLLIVGTTLSIQSVKTLAVNFKSKGGYVIFISNEMPSDKKGIDLIVLGDCQKL------------------
>tr|G0W721|G0W721_NAUDC Uncharacterized protein OS=Naumovozyma dairenensis (strain ATCC 10597 / BCRC 20456 / CBS 421 / NBRC 0211 / NRRL Y-12639) GN=NDA
--------LSELKKITRKPTLKYRPIVNTVQDNLCSFKYSNKIIVIAGAGISTATGIPDFRSNSSSKEG-ETKSLFDYNYVYSNDDSIEKFNKLMNHLNH
SNTVKPTKFHHFLNDLLEK-NKIQRIYTQNIDGLEKKAVSNKIVQLHGDINFMTCNFCHIRTSYDPT-QLIPDCLYCMEIGKFRPSIVLYNELHPSGEEI
KIDLKFPDLLVIVGTTLKIPGVISMVKNFKSRKGIILFIANELPSQDGHIDLIVLGDCQAI------------------
>tr|G0VBR3|G0VBR3_NAUCC Uncharacterized protein OS=Naumovozyma castellii (strain ATCC 76901 / CBS 4309 / NBRC 1992 / NRRL Y-12630) GN=NCAS0B03050 PE=4 
--------ITQLKK-PRKPPLRYRPIENTLRDELYALTHCQRIVVIAGAGISTHAGIPDFRSS--SKSS-STKSLFDYNYVYSDNETTLRFNTLMNKLNK
SREASPTKFHTFLNELASQ-GRLLRSYTQNIDGLENKL--EKTIQLHGDVNLMSCTLCHKTSPYDSTGSLVPDCTHCMEIGKLRPKVILYNELHPDGEEI
RLDVKVPDCLIIVGTTLRIPGVINMVKAFRSRKGIILLITNEPPSQKGNTDLVVLGDCQEL------------------
>tr|C5DSZ8|C5DSZ8_ZYGRC ZYRO0C04246p OS=Zygosaccharomyces rouxii (strain ATCC 2623 / CBS 732 / NBRC 1130 / NCYC 568 / NRRL Y-229) GN=ZYRO0C04246g PE=4 
--------LPQLKKSNRKPRLKYRPDPFSLNDDAYALRHSKRIVTVAGAGISVAAGIPDFRSKTGLFKSSSGKDLFDFNQVYSCDEMSIKFNGMITDLHR
AQESQSTAFHSMLNEIAAE-GRLQRLYTQNIDGLDTRLTHPVTIQLHGSINHVECNMCSKIDKLDPSTQVVPTCSQCEEVGKLRPRVVLYNEMHPEGDLI
SHDIKKPDCLIVVGTSLQIPGVKQLCKQFRARKGIVLYLNKDLPSQDGWVDLIVLGDCQDV------------------
>tr|W0VIU0|W0VIU0_ZYGBA Probable NAD-dependent histone deacetylase HST4 OS=Zygosaccharomyces bailii ISA1307 GN=ZbHST4 PE=4 SV=1
--------LTQLRGSNRKPRLKFRPQPFTLNDNAYALRHCRRIVVIAGAGVSVAAGIPDFRSKEGLFSSASGKDLFDYNQVYSSDEMSYKFNGMIANLHR
SQGAQPTAFHSMLDEIASE-GRLQRLYTQNIDGLDTRMKHPVTIQLHGSVNHVECNMCSKIENFDPSAQVVPTCPQCEEIGKLRPRVVLYNEVHPEGDLI
ASDLKKPDCLIIVGTSLQIPGVKSLCKQLADRKGIILYMNKELPTKDGSIDLIVLGDCQEV------------------
>tr|G8ZXI7|G8ZXI7_TORDC Uncharacterized protein OS=Torulaspora delbrueckii (strain ATCC 10662 / CBS 1146 / NBRC 0425 / NCYC 2629 / NRRL Y-866) GN=TDEL0
--------LKQLKTRSRKPRLKYRPEPNTLDDNAYALQHSRRVIMVTGAGISVAAGIPDFRSSNGLFSQSSGKELFDYNNVYSSDEMNMKFNKMISSLHD
SKRSTPTNFHHMMDEIALE-GRLQRLYTQNIDGLDTRLLNPQTVQLHGSIHHMECNKCSIVADMDTAAQVVPTCAQCEEVGKMRPRVVLYNELHPEGDII
NSDLKKPDCLIIAGTSLQIPGVKAICKQFRDSKGIVLYMNQEMPKRDGHIDLLVLGDCQNV------------------
>tr|G8BZX2|G8BZX2_TETPH Uncharacterized protein OS=Tetrapisispora phaffii (strain ATCC 24235 / CBS 4417 / NBRC 1672 / NRRL Y-8282 / UCD 70-5) GN=TPHA0L
--------VLQLTKAARKSRLKYKPALNEIDENEHVLLQSKKIVVVAGAGISVEAGIPDFRSSDGLFTMASGKELFDFNRVYSSDEMSKQFNLMIKKLHH
SKNSVPTDFHKYLNELSKS-GRLLRVYTQNIDGLETRLSHPNIIQLHGSIHHMQCNKCRKVSGMEPTIEYVPSCKECMEVGKMRPRIVLYNEVHPEGDII
NMDMKKPDCLIIAGTSLNIPGVKSMCKQFRTSKGYVIYVNKELPSKDGGVDLIVLGDCQNI------------------
>tr|J7S3R6|J7S3R6_KAZNA Uncharacterized protein OS=Kazachstania naganishii (strain ATCC MYA-139 / BCRC 22969 / CBS 8797 / CCRC 22969 / KCTC 17520 / NBR
--------LSQLKS-----KSRRR-TPFHKNRKLSVLNDCENIVMITGAGTSTHCGIPDFRSQNGMYTKAATKSLFDMNSIYSDTEQIQRFNQLITSLRE
SCKSTPTPFHQFINKLAQQ-GRLRRLYTQNIDSLETKLPSPVLIQLHGSVHYTQCTKCNHVTRLDPSKPLIPLCKHCAEVGKLRPRITLYNEPHPEGDII
NLDTTSVDCLMIVGTKLDIIGVKQICSNFQKRRGVVIFISDELPDRDGGIDLIVHGDCQRV------------------
>tr|A0A0A8L730|A0A0A8L730_9SACH WGS project CCBQ000000000 data, contig 00049 OS=Kluyveromyces dobzhanskii CBS 2104 GN=KLDO_g2339 PE=4 SV=1
--------INDLKRKSRKPRLRYRPELNTLDDDAYVLKHSKRIIVVQGAGISVAAGIPDFRSANGLFTTKSGKDLFDFNHVYSSDSMSISFNSLMSTLYS
SRTSKPTAYHSFISQLCEN-NQIKRIYTQNIDGLENETQKSLVVQLHGSIHHMSCLKCKKKYAMDPSGEIVPQCPECKEVGKLKPSVVLYNEYHPEGDTI
NKDISNPDALIIVGTSLKIPGVKQMVKQFRTKKGFVIWINREPPPPNNGYDLIVSGDCQNL------------------
>tr|W0TGI2|W0TGI2_KLUMA NAD-dependent histone deacetylase HST4 OS=Kluyveromyces marxianus DMKU3-1042 GN=KLMA_50570 PE=4 SV=1
--------INELQKRCRRSKVKYRPELDSLDADASVLTNSKKIIVVQGAGVSVAAGIPDFRSSDGLFTTKSGKDLFDFNNVYSSNSMSISFNNLMSQLYH
SSNCKPTSYHKFINNLVEN-KQVKRIYTQNIDGLETKFPSSIIVQLHGSIKHMSCLKCKKVYDMDPSGEIVPQCPECKEIGKLKPNVILYNEYHPEGDII
NKDLSNPDTLLIVGTSLQIPGVRQMVKQFRSKKGSVIWINCEKPSPKKGCDLIVLGDCQNI------------------
>tr|Q6CQA7|Q6CQA7_KLULA KLLA0D18535p OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) GN=KLLA0_D18535
--------INDLSRTTRKPRLKYRPELDTLDNDAYVLSYSKRIVVVQGAGVSVAAGIPDFRSANGLFTTKSGKDLFDFNHVYSSNSMSISFNSLMSKLHS
SCTSKPTAYHSFINQLCEK-NQVKRIYSQNIDGLETKFQTPQVVQLHGSIHHMSCMKCRKKYDMDPSGEIVPQCPECKEVGRLKPSVVLYNEYHPEGDII
NKDLSNPDALLIVGTSLKIPGVRQMVKQFRAKKGFIIWVNNELPPPTNRCDLVVLGDCQNL------------------
>tr|A0A0C7N4A2|A0A0C7N4A2_9SACH LALA0S03e02938g1_1 OS=Lachancea lanzarotensis GN=LALA0_S03e02938g PE=4 SV=1
--------LPALRKKTRKPRLKYRPQPNSLSLNAYALQHSKRTVVIAGAGVSTDAGIPDFRSSEGLFSTSSGKDLFDYNVVYSNAEMGLRFNRLIAGLHE
CLQVSPTRFHNFLNSMAQE-GRLRRLYTQNIDALEDQTTHPATIQLHGSIKHMSCNKCSKIYGLDPSREVVPLCPQCSEVGKLRPRVVLYNETHPEGETI
TNDLNKPDCLIIVGTTLKIPGVRSMCKQFHDARGIVVWINTELPAKDECIDIIIVGDCQMV------------------
>tr|A0A0P1KR29|A0A0P1KR29_9SACH LAQU0S04e08790g1_1 OS=Lachancea quebecensis GN=LAQU0_S04e08790g PE=4 SV=1
--------FPELRKKARKPPLRYRPERNTIDQNAYAFEHSRRVVMVAGAGVSVAAGIPDFRSSGGLFSTASGKELFDFNRVYSSAEVGLKFNRMIADMHA
CQETRPTEFHRLANTIAKE-GRLTRLYTQNIDSIEDGMSHPKTVQLHGSIRHMFCNKCSKIYDMDPSREVFPLCPQCTEVGKLRPRIVLYNEIHPEGESI
SKDLGRPDCLIIVGTTLKIPGVRAMCKQFHQSNGIVLWLNTELPTKDGFIDLIVVGDCQKV------------------
>tr|I2H8A0|I2H8A0_TETBL Uncharacterized protein OS=Tetrapisispora blattae (strain ATCC 34711 / CBS 6284 / DSM 70876 / NBRC 10599 / NRRL Y-10934 / UCD 7
--------LPTLLEIVRKPRLKYRPINNTIDTELYSFKYCKNMIVVTGAGISVASGIPDFRSSEGIFKT-NGKDLFDYNFVYSNDANILKFNKMLNSLHQ
SNKSKPSKFHYFLNDLSSM-GKLKRLYTQNIDCLDTNLDHPKTIQLHGSLNDVICNKCDYKIAYNPCNALVPECPQCQEIGKLRPRVILYNEFHPEGDII
SLDLSRLDCLVIVGTSMKIPGVKSMCKEFRKSKGYILFINKEMPSKDGGVDLIVLGDCQIL------------------
>tr|M9N6D6|M9N6D6_ASHG1 FAGL118Wp OS=Ashbya gossypii (strain FDAG1) GN=FAGOS_FAGL118W PE=4 SV=1
--------LPALRKVRRKPRLTYRPATNSLAHDAYALQHSRDIVVVTGAGISVAAGIPDFRSSDGLFATKSGKHLFDFNHVYSSDDMSMQFNRMIVDIHG
SQRFEPTEFHRLLDGLAQQ-GRVRRIYTQNIDCLENKLANPKTIQLHGSINHMCCNKCRKIYDMDPTGDVIPVCPECEEVGKLRPYIVLYNEVHPEGEKV
AKDLLKCDCLIIVGTSLQIPGVKTICRQFRARKGIVLWVNKELPTQDGGMDLIIVGDCQDL------------------
>tr|G8JT95|G8JT95_ERECY Uncharacterized protein OS=Eremothecium cymbalariae (strain CBS 270.75 / DBVPG 7215 / KCTC 17166 / NRRL Y-17582) GN=Ecym_4171 P
--------LPALKMLKRKPRLKYRPERNSVDDDAYAFMHCKNIVAITGAGISVAAGIPDFRSSDGLFASGSGKRLFDFNYVHSSEEMNIKFNKMISDMHT
CQVLEPTRFHKLLNILSIS-GRLRRIYTQNIDCIENKLDGPTTIQLHGSINHMSCTKCRKIYDMNTERSVIPVCPECEEVGLLRPYIVLYNEVHPVGEKV
MKDLLKCDCLLIVGTSLKIPGVKTICKQFRSRKGIILWINRDMPSQDGGVDLFVLGDCQDL------------------
>tr|F6SLD6|F6SLD6_CIOIN Uncharacterized protein OS=Ciona intestinalis GN=sir2-c PE=4 SV=2
---------SIISEPKRRKKLDTVNTL---SDAIRLIKTSKKILVLTGAGVSVSCGIPDFRSRDGIYSRLNPQAMFDIHYFKHDPRPFFKFAKE---IY-
PGQFKPSRAHRFISLLEKT-GRLLRNYTQNIDTLEQVAGISKVVQCHGSFATASCCSCDYKTNCEADIQVVPHCPRCPSPGVIKPDIVFFGENLPQFHQM
TSDKDDADLLIVIGSSLKVRPVALIPNSIPD-HIPQLLINREPLSH-MTFDIELLGDCDVILSEISKRLGGEFN-----
>tr|T1KPX6|T1KPX6_TETUR Uncharacterized protein OS=Tetranychus urticae PE=4 SV=1
------------------------PHVNTLDDVVELIKKCKNIIVLTGAGVSVSCGIPDFRSANGIYARPDPQAMFDIEYFRDDPRPFFKFAKE---IY-
PGQFQPSIAHKFIKLIEDK-GKLLRNYTQNIDTLEKAAGIEKVITCHGSFATATCTVCGYKTNSDEDIQRLPLCPKCPETPVIKPDIVFFGESLSEFHSM
AMDKDKCDLLIVMGSSLKVRPVALIPTAIPP-EVPRILINRESLKH-ICFDVELLGDCDDVVQQICRKIGGDW------
>tr|K7TXK8|K7TXK8_MAIZE Uncharacterized protein OS=Zea mays GN=ZEAMMB73_713945 PE=3 SV=1
--------------------------------FYQFIDKSKRLMVVTGAGMSTESGIPDYRSPNGAYSTFKPLSQASSFFFLALLLAQRRYWA--RSYAG
FRRAQPNAAHYALASLERI-GRVHSMVTQNVDRLHHRAG-SNPLELHGSVYEVICLECGTSISREQDVFEIPSCHQCG--GVLKPDVVMFGDNVPRAESA
KEAARTCDALLVVGSALMTMSAFRLARLAHEANAPIAAVSIGETRADSILSLKINARCGEILPRILQM-----------
>tr|A0A0D2D8E1|A0A0D2D8E1_9EURO Uncharacterized protein OS=Cladophialophora immunda GN=PV07_03565 PE=4 SV=1
------RRLSSPAKRVPQIRPRLN-QYYTLDHAVSLLKSSKNIIVLTGAGISTSLGVPDFRSANGVYNLDDPQELFHIDNFKADPEE---FFKQAAKVFP
PDVPKYSLTHAFISMLQSK-GKLLTNYTQNIDGLELAAGVSKLIQCHGTLATATCMSCGKRTTARKYAGGVPYC-KCTLKGLLKPDMTFFGEDIASAPRL
KIDKSKVDLLVIVGTSLKVEPVNEMLLNIPV-TVPQIWISKDRCQREVKVDIELLGECDLVLEEIARR-----------
>tr|A0A0D1YGE4|A0A0D1YGE4_9EURO Uncharacterized protein OS=Exophiala sideris GN=PV11_07529 PE=4 SV=1
------RRLDSPTKNAPQIRPRLQ-QYHTFDHAVSLFKSSKNIVVLTGAGISTSLGVPDFRSQNGVYNLDDPQELFHIANFKTDPGE---FFKQAAKVFP
PSVPKYSATHAFLAMLQSK-GKLLTNYTQNIDGLEVAAGLSKVIQCHGTLATATCMTCGKRTTARKYAGKIPFC-KCSLKGLMKPDMTFFGEPISAAPRL
EDDTTKVDLLVIIGTSLKVEPVNDMPLVIPP-QVPQIWISKDRCTRDVKVDIELLGECDLILEEIARR-----------
>tr|A0A0D2IPA7|A0A0D2IPA7_9EURO Rhinocladiella mackenziei CBS 650.93 unplaced genomic scaffold supercont1.4, whole genome shotgun sequence OS=Rhinocladiella ma
------RRLSSPSKNISQVRPRLN-QYYTLDHAVSLFKSSKNIIVLTGAGISTSLGVPDFRSTSGIYNLDDPQELFHIDNFKSDPNE---FFKQAAKVFP
PDVPRYSLTHAFISVLQSK-GKLLTNYTQNIDGLEAAAGVSKLIQCHGTLSTATCMSCGRKTTARKYAGGIPFC-KCSLKGLLKPDMTFFGEHISSAPRL
EVDKSKVDLLVIIGTSLQVEPVNDMLLAIPP-TVPQIWISKDRCQRQVKVDIELLGECDLILEEIARR-----------
>tr|W9Y5Z0|W9Y5Z0_9EURO Uncharacterized protein OS=Capronia epimyces CBS 606.96 GN=A1O3_05725 PE=4 SV=1
------RRLSSPLKNVSQIRPRLN-QYYTLDHAVSLFKSAKNIIILTGAGISTSLGVPDFRSTDGIYNLDDPQELFHIDNFKADPAE---FFKQAAKVFP
PSVPRYSSTHAFVAMLQSK-GKLLTNYTQNIDGLEIAAGVSRLIQVHGTLATATCMSCGKQTTARKYAGGIPFC-KCSLKGLLKPDMTFFGEHISSAPRL
DTDKRKADLLVIVGTSLKVAPVNDMLLAIPP-TVPQIWISKDRCQRQVKVDIELLGECDLILEEIARR-----------
>tr|H6BW15|H6BW15_EXODN NAD-dependent histone deacetylase SIR2 OS=Exophiala dermatitidis (strain ATCC 34100 / CBS 525.76 / NIH/UT8656) GN=HMPREF1120_04
------HRLSSPFADVPQIRPRLN-QYYTIDHAVSLFKTCKNIVILTGAGISTSLGVPDFRSSNGVYALDDPQELFHIDNFKANPEE---FFKQAAKVFP
PGVPRYSSTHAFIAMLQSK-GKLLTNYTQNIDGLETAAGISKLIQVHGTLATATCMSCGKKTTARKYAGDIPVC-KCSLKGLLKPDMTFFGEHISSAPRL
EEDRDKIDLLVIIGTSLKVAPVNEMLTAIPP-TVPQIWISKDRCQRQVKVDIELLGECDVVVEEIARR-----------
>tr|A0A0D2EAK2|A0A0D2EAK2_9EURO Uncharacterized protein OS=Exophiala xenobiotica GN=PV05_08010 PE=4 SV=1
------RRLSSPVKKAPQVRPRLN-QFYTFDHAVQLFKRSKNIIVLTGAGISTSLGVPDFRSTNGVYNLDDPQELFHIDNFKTDPGE---FFKQAAKVFP
PDVPRYSATHAFLALLQAK-GKLLTNYTQNIDSLETAAGVAKLIQCHGTLSTATCMSCGKRISARKYEGNTPFC-KCSRKGLLKPDMTFFGEHISSAPRL
EVDKAKVDLLVIIGTSLKVAPVNDMLLAVPS-TVPQIWISKDRCQREVKVDIELLGECDLIIEEIARR-----------
>tr|A0A0D2BPB7|A0A0D2BPB7_9EURO Uncharacterized protein OS=Exophiala spinifera GN=PV08_08116 PE=4 SV=1
------RRLSSPAKNISQIRPRLN-EYYTFDHAVQLFRRSKNIIILSGAGISTSLGVPDFRSTNGVYNLDDPQELFHIDNFKMDPGE---FFKQAAKVFP
PNVPRYSATHAFIALLQAR-GKLLTNYTQNIDGLEIAAGVDKLIQCHGTLSTASCMSCGKRVSARKYQGNIPFC-KCSLKGLLKPDMTFFGEHISSAPRL
NIDKTKVDLLVIIGTSLKVAPVNDMLLAVPP-TVPQIWISKDRCQREVKVDIELLGECDLIVEEIARR-----------
>tr|A0A072P245|A0A072P245_9EURO Uncharacterized protein OS=Exophiala aquamarina CBS 119918 GN=A1O9_10771 PE=4 SV=1
------RRVASPAKKV-QVRPRLN-QYYTIDHAVSLFKKSKNIVVLTGAGISTSLGVPDFRSKTGVYNLNDPQDLFHIDNFKTNPEI---FFKQAKKIFP
PEVPKYSSTHAFISLLQAK-GKLLTNYTQNIDGLETVAGVTRLIQCHGSLSTASCMSCGKQVSAKKYGGSIPVC-KCSMKGLLKPDMTFFGEHVSSAPRL
ASDKSKVDLLVIIGTSLKVAPVNEMLFMVPP-TVPQIWISKERCQREVKVDIELLGECDLIIDEICRR-----------
>tr|W9YAD8|W9YAD8_9EURO Uncharacterized protein OS=Capronia coronata CBS 617.96 GN=A1O1_06601 PE=4 SV=1
------RRLSSPLKEGLQIRPRLN-QYYTLDHAVALFKSAKNIVTLTGAGISTSLGVPDFRSKNGVYDLNDPQELFHIDNFKADPDE---FYKQAAKVFP
PKVPKYSPTHAFIAMLQSK-GKLLTNYTQNIDGLEAAAGVDKLIQVHGTLATASCMTCGKRTTARKYAGGIPFC-KCSLKGLLKPDMTFFGEHISSGPRL
EMDKGKVDLLVIIGTSLKVAPVNDLLLAIPP-TVPQIWISKDRCQRQVKVDIELLGECDLVLEEIARR-----------
>tr|A0A0D1Z2B4|A0A0D1Z2B4_9EURO Uncharacterized protein OS=Exophiala mesophila GN=PV10_08563 PE=4 SV=1
------RRTMSPAKG--QTRPRLN-QYYTIDHAVSLLQSKKNIVVLTGAGISTSLGVPDFRSSQGVYSLNDPQELFHIDNFKEEPQE---FFRQAAKVFP
PSVPRYGPTHAFISMLEAK-GKLLTNYTQNIDGLETAAGVSKLIQCHGTLSTASCMSCGKQVTARKYAGNIPFC-KCSQKGLLKPDMTFFGEHVASATRL
DIDTMKVDLLVIIGTSLKVAPVNQMLLKIPS-SVPQIWISKERCTREVKVDIELLGECDLIVQELCRR-----------
>tr|G7YSW3|G7YSW3_CLOSI NAD-dependent deacetylase sirtuin-1 OS=Clonorchis sinensis GN=CLF_109731 PE=4 SV=1
---------------TPRPRLPQVNTL---EKVVELLQSSRFILVVTGAGISVSCGIPDFRSRDGIYARLSPQSMFDMSYFLRNPLPFFKFAKEI---F-
PGQFAPSLTHRFVALLESK-GTLLRNYTQNIDTLEQAAGITRLIQCHGSFATATCTSCKYQVSGDEITQSIPYCPRCHPFGVLKPDIVFFGEDLSEFDTL
AGDVEKADLVLVIGSSLKVRPVAHIPNSIPE-SVPQILINREPLTN-HDFDVELLGDCDVIVNELCHHLNW--------
>tr|U5H4R3|U5H4R3_USTV1 Uncharacterized protein OS=Microbotryum violaceum (strain p1A1 Lamole) GN=MVLG_02300 PE=4 SV=1
-----------------RDRLEQHSTV---DDVVELIRKSKNIMVLTGAGVSTSCGIPDFRSPTGLYAKEDPQQMFDLDYFKEKPNVFYSFAKE---IY-
PSNFTPSPCHRFVKVLEDN-DKLLRNYTQNIDGLFERAGVRKMLNCHGSFATASCLRCRTQFPGSADVSRVPLCPHCTAKPLIKPDIVFFGEPLPTFDRS
LLDREQVELLIVIGTSLRVSPVATIVSQLP-HSVPQVLINRDPIT-HANFDVVLLGDGDTIVTHLCGRLGKAFE-----
>tr|W4YSD6|W4YSD6_STRPU Uncharacterized protein OS=Strongylocentrotus purpuratus GN=Sp-Sirt1 PE=4 SV=1
------------------------------DDAIQLLKTCKNILVLTGAGVSVSCGIPDFRSRDGVYARPDPQAMFEISYFRKDPRPFYKFAKE---LF-
PGQFKPSTSHKFISQLEEH-QKLLRNYTQNIDTLEQAAGIKGVIQCHGSFATATCTRCGLSVDSDDDVQMIPICPQCGPMAVLKPDIVFFGEGLPFYDKL
NDDKETADLLIVMGSSLKVRPVATIPSLLPK-KVPQILINREPLPH-LNFDIELLGDCDVIINEILHRLGDGWDH----
>tr|E4Y6Z5|E4Y6Z5_OIKDI Uncharacterized protein OS=Oikopleura dioica GN=GSOID_T00025298001 PE=4 SV=1
---------------------------LSLDDIVDLIKKSKNIMILTGAGISVSCGIPDFRSKNGLYAKLDPPSMFCLKFFKGDQRPFFRFAKE---IY-
PGSFKPSPSHRFIAELEQR-GKLLRNFTQNIDGLEQEAGIKNVIQCHGHFHTATCLDCQAKYKSSEDIQQIPRCKRIRT-KIIKPDIVFFGENLPHFHKA
VDEKDKADLLIVMGSSLKVGPVNEIPDALD-KSVPAILINRESLRYASEFDGELLGNCDDIVAILAKKL----------
>tr|A0A0C3L6D4|A0A0C3L6D4_9HOMO Uncharacterized protein OS=Tulasnella calospora MUT 4182 GN=M407DRAFT_242626 PE=4 SV=1
-------------------------------------DECKNVFLMVGAGISTSAGIPDFRSPTGLYANLYPEAVFDIRYFSQNPKP---FYTLAAELY-
PGYYRPTITHSFIRLLAEK-GKLYTCFSQNIDTLERRAGVEKIFEAHGSFATQRCIKCKTEYPSEEMMAEVPHCTSCD--GVVKPDIVFFGEGPDTFESA
IRNLEEADLLIIMGTSLTVYPFAALRSMVPA-KCPRVLINLDRVGDGAADDVALLMPCDEAVRKLCDEIGDGWT-----
>tr|S3CLX1|S3CLX1_OPHP1 Sir2 family protein OS=Ophiostoma piceae (strain UAMH 11346) GN=F503_00235 PE=4 SV=1
-------------------------------------GKARRIVVLTGAGISTAAGIPDFRSPTGLYANLYAEAVFSIDYFRENPNP---FYVLAKELY-
PGQYHPTVSHVFLALLARK-GLLKMLFTQNIDCLERATGIDLIVEAHGSFATQRCIECRMVFPDKEHVASVPICPNCGKPGLVKPDIVFFGESLPRFHEL
HAAASDVDLVLVLGTSLSVFPFASLPKLAP-ESVPRVLFNREAVGFGTRDDVLSLGICDAGIRKFAEAL----------
>tr|F0XJ94|F0XJ94_GROCL Sir2 family histone deacetylase OS=Grosmannia clavigera (strain kw1407 / UAMH 11150) GN=CMQ_2489 PE=4 SV=1
-------------------------------------GRARKIVALTGAGISTAAGIPDFRSPTGLYANLYAEAVFSIDYFRQNPRP---FYVLAKELY-
PGQFHPTVSHAFLALLACK-GLLNMLFTQNIDCLERAAGVDRIVEAHGSFATQRCIDCGTAFDDAAHVARVPRCGQC--GGLVKPDIVFFGESLPRFHEL
HETPDGTDLLLVLGTSLTVYPFAGLPSLAP-DGVPRVLFNREQVGLGERDDVLALGSCDDGVRRLAAAL----------
>tr|A0A0K6FNZ2|A0A0K6FNZ2_9HOMO NAD-dependent histone deacetylase SIR2 OS=Rhizoctonia solani GN=hst2 PE=4 SV=1
--------------------------------------GKRKVVLMVGAGISTSAGIPDFRSPTGLYANLYPEAVFDIHFFRDNPLP---FYTLAHELY-
PGKFRPTITHSFIKLLSDK-GMLHMCFTQNIDTLERLAGVEKLIEAHGSFAENHCIDCGAEFPSDEMVVNIPKCKKCG--GLVKPDIVFFGESLQKFHDS
VHTLPFADLALVIGTSLTVHPFARLPEMVSD-RCPRALLNMEPAGNFGRADVVHLAPCDDAVRELCDLLG---------
>tr|L8WN28|L8WN28_THACA Sir2 family histone deacetylase Hst2 OS=Thanatephorus cucumeris (strain AG1-IA) GN=AG1IA_06616 PE=4 SV=1
--------------------------------------GKKKVVLMVGAAPRLG--FLTLDPPRGYPTPGATLAVFDIHFFEQNPLP---FYTLAHELY-
PGKFRPTVTHSFIKLLSDK-GMLQMCFTQNIDTLERLAGVSQLVEAHGSFAENHCISCGAEFPADEMVVNVPRCKNCG--GLVKPDIVFFGESLERFHES
LSLLPFADLALVIGTSLTVHPFARLPQMVSD-RCPRALLNMETAGQFNR---IRLAPCDDAVRELCDLLG---------
>tr|A0A074YG42|A0A074YG42_9PEZI Uncharacterized protein OS=Aureobasidium subglaciale EXF-2481 GN=AUEXF2481DRAFT_5276 PE=4 SV=1
------------------------------------EGHAKRIVVMTGAGISTSAGIPDFRSPTGLYANLYAEAVFDISFFRENPTP---FYTLAHELY-
PGKYRPTVTHSFIRLLHEK-GLLLKLFTQNIDCLEREAGVESIIEAHGSFARQSCIDCKSPYPQEEEAKTIPRCHKCH--GLVKPEIVFFGEQLPAFFDN
IDVPTEADLCIVLGTSLQVQPFASLPGACK-SGVPRVLINMERVGGLRSDDVLLLGDCDAGVRKLAKAI----------
>tr|E0W166|E0W166_PEDHC NAD-dependent deacetylase HST1, putative OS=Pediculus humanus subsp. corporis GN=Phum_PHUM569840 PE=4 SV=1
--------------------------INTLEDAVNLIKTSQNIMVLTGAGVSVSCGIPDFRSRNGIYSRPDPQAMFDIQYFNKDPRPFFKFA---RDIY-
PGQFKPSPCHRFIRALEQK-GKLLRNYTQNIDTLEQVAGIEKVIQCHGSFATASCTRCKRKVQADEDVQKIPICVTCEQRGIMKPDITFFGEGLEDFHEA
MGDKDKCDLLIVIGSSLKVRPVALIPSSIPA-SVPQILINLEPLPH-LNFDVELLGESDVIVDHICRLLGEEWE-----
>tr|R9P7H9|R9P7H9_PSEHS Transcription regulator OS=Pseudozyma hubeiensis (strain SY62) GN=PHSY_004908 PE=4 SV=1
--------------------LPQYNTI---TDALSLISTRSKIMILSGAGISVSCGIPDFRSHDGIYASDDPQDMFDKSYFLTNPSMFYSFAHR---IF-
PSNFTPSSTHRFIKLVEEQ-GKLLRNYSQNIDTLEQLAGIEMVLQCHGSFASASCTDCGYRCKGSDAIKRVPRCPRCEEFGILKPDITFFGEKLSDFDHA
LADREEVDLLIVMGTSLKVAPVSEILGHIP-HSTPVILINKTPIL-HLATDIMLLGDCDRIVEYLCRKLG---------
>tr|V5F3L0|V5F3L0_PSEBG Uncharacterized protein OS=Pseudozyma brasiliensis (strain GHG001) GN=PSEUBRA_SCAF1g00553 PE=4 SV=1
--------------------LPQYNTV---DDALQLLSTRRRIMVLSGAGISVSCGIPDFRSKDGIYSTDDPQDMFDKQYFLSNPSMFYSFAHR---IF-
PSNFVPSSAHRFIKLLEDR-GQLLRNYSQNIDTLEQIAGIEKVLQCHGSFASASCTDCGYTCKGSADIQRVPKCPRCEQFGILKPDITFFGEKLDKFDHA
LADREHVDLLIVMGTSLKVAPVSEILGHIP-HSTPVILINKTPVL-HLATDIMLLGDCDRIVQYLCRKLG---------
>tr|E6ZT06|E6ZT06_SPORE Related to HST1-silencing protein OS=Sporisorium reilianum (strain SRZ2) GN=sr12260 PE=4 SV=1
--------------------LPQYNTV---ADAIGLLATRKRVMVLSGAGISVSCGIPDFRSKDGIYATDDPQDMFDKQYFLANPAMFYSFAHR---IF-
PSNFVPSCAHRFIKLLEDR-GQLLRNYSQNIDTLEQVAGIQRVLQCHGSFASASCTDCGYTCKGSGAIQKVPSCPRCDEHGILKPDITFFGEKLDTFDHA
LADRDHVDLLIVMGTSLKVAPVSEILGHIP-HSTPVILINKTPIL-HLATDIMLLGDCDRIVEYLCRKLG---------
>tr|A0A0D1CD62|A0A0D1CD62_USTMA Chromosome 2, whole genome shotgun sequence OS=Ustilago maydis (strain 521 / FGSC 9021) GN=UMAG_00963 PE=4 SV=1
--------------------LPQYNTI---SDALDLLSTRKRIMILSGAGISVSCGIPDFRSKDGIYAIDDPQDMFDKTFFLSNPSMFYSFAHK---IF-
PSNFVPSSAHRFIKLIEER-GQLLRNYSQNIDTLEQLVGIERVLQCHGSFASASCTDCGFRCKGSEAIQSVPSCPRCEQFGILKPDITFFGEKLSSFDHA
LADREQVDLLIVMGTSLKVAPVSEILGHIP-HSTPVILINKTPIL-HLATDIMLLGDCDRIVEYLCRKLG---------
>tr|A0A023ESR7|A0A023ESR7_AEDAL Putative sirtuin 5 (Fragment) OS=Aedes albopictus PE=2 SV=1
--------------------------------------GFKKIVTMVGAGISTSAGIPDFRSPTGLYNNLYPQAIFELEYFYQNPKP---FFQLAKELY-
PGTFKPTPSHYFVKLLEQK-GLLIRHYTQNIDTLERIAEIEKIVEAHGTFFTNHCLQCRAAYTLDFKTDEIPTC-ACG--GVIKPDIVFFGEGLPRFHLP
HKDFAECDLLIIMGTSLTVQPFASLVEYVND-DCVRLLINRDKVGGGGRRDVAWTGDCDDGCLFLADKL----------
>tr|A0A0D6ESS5|A0A0D6ESS5_SPOSA SPOSA6832_04675-mRNA-1:cds (Fragment) OS=Sporidiobolus salmonicolor GN=SPOSA6832_04675 PE=4 SV=1
----------------NRDRLEQYQTV---DDVVNLIRKSKRILVLTGAGVSTSCGIPDFRSPTGLYARDDPQDMFDLSYFRERPDVFYGFAKE---IY-
PSNFVPSPCHRFVRLLELN-DKLLRNYTQNIDGLFEQVGVERMLNCHGSFASASCLLCHRRFPGSSDVQRVPLCPFCVAKPLIKPDIVFFGRTDEL----
-------SWV----YVVGVSPVAQLPSHLP-HSIPQILINRDPVGH-HNFDICLLGDGDTIVRFLCRKLAEA-------
>tr|G7E9G8|G7E9G8_MIXOS Uncharacterized protein OS=Mixia osmundae (strain CBS 9802 / IAM 14324 / JCM 22182 / KY 12970) GN=Mo05982 PE=4 SV=1
----------------RRERRTDVSTL---EDALRQIKTARNIIILSGAGVSTSCGIPDFRSSDGIYAKDEPQQMFDLQFFRHNPQVFYSFAHS---LY-
PSNFLPSRTHSFIRLLEKH-GKLLRNYTQNIDTLEQRAGIKRVLNCHGSFATASCMRCRRAFPGEEDVKRVPLCPYCTAKPILRFDICLFGEPLPDEFDL
CLDREKIDLLIVIGSSLSVAPVSELTAHIP-HSVPQILINRDPTPH-VNFDVCLLGDCDVVVSWLCDQLAKA-------
>tr|A0A0K3CIH1|A0A0K3CIH1_RHOTO FGENESH: predicted gene_8.474 protein (Fragment) OS=Rhodosporidium toruloides GN=FGENESH: predicted gene_8.474 PE=4 SV=1
----------------NRDKLMEYNTP---QDVVDLIRKSKRILILTGAGVSTSCGIPDFRSSTGLYARDDPQDMFDLAYFKRSPNVFYSFAKE---IY-
PSNFVPSPCHRFVRLLEME-GKLLRNYTQNIDGLFEQVGVERMLNCHGSFATASCLICRRRFPGTPDVSRVPLCPFCTPKALIKPDIVFFGEALSDEFDH
RLDREEVDLLIVMGTSLRVSPVAQLPSHLP-HSIPQILINRDPLPH-QNFDVCLLGDGDTIVRWLCEELGKS-------
>tr|A0A026W6E6|A0A026W6E6_CERBI NAD-dependent deacetylase sirtuin-6 OS=Cerapachys biroi GN=X777_09873 PE=4 SV=1
-------------------------------LLAEWIQGARHVVVHTGAGISTAAGIPDFRGTNGVWTLEQKG-L--------KPTMS----------IS
FDEAIPTKTHMALKKLIEA-KKVKFIISQNIDGLHLRSGIQHLAELHGNMFTEQCDKCGRQFIRNFATKLDTVCRPCR--GRMHDTILDWEHNLPDLSLS
DLHSSVADLSICLGTTLQIIPSGNLPLYTKKYGGRLVICNLQPTKHDKKADLIVNGNVDEIIVAVMKKLGVE-------
>tr|B7QJK7|B7QJK7_IXOSC Chromatin regulatory protein sir2, putative OS=Ixodes scapularis GN=IscW_ISCW014656 PE=4 SV=1
-------------------------------RLADWMQSSKHVVVITGAGISTSAGIPDFRGPNGVWTLEQKG-E--------KPTLN----------IS
FDDAVPTPTHMALVALAER-AKLQFLVSQNVDGLHLKSGFDTLADLHGNMFVDRCNQCRRQFIRDTATRTGEPCPLCR--GRLHDSILDWEDELPAIEAA
DAHCRVADLVLCLGSTLQIVPCGTLPLLAKKSAGKIIVCNLQPTKLDKSANLILRAYVDDVMTKLMAKLGID-------
>tr|K7IVH1|K7IVH1_NASVI Uncharacterized protein OS=Nasonia vitripennis GN=LOC100113582 PE=4 SV=1
-------------------------------LLADWIKGARHVVVHTGAGISTSAGIPDFRGPNGVWTLEQKG-L--------KPDSS----------TS
FDEAIPTKTHMALKKLIDT-NKVKFIISQNIDGLHLRSGVQYLAELHGNMFVEQCDKCGRQFIRNFATKLETVCRPCR--GKMHDTILDWEHNLPDLALA
DLHSSVADLSVCLGTTLQIIPSGNLPLYTKKYGGRLVICNLQPTKHDKKADLIINGKLDDVIESVMKKLGLE-------
>tr|W4XPP2|W4XPP2_STRPU Uncharacterized protein OS=Strongylocentrotus purpuratus GN=Sp-Sirt3 PE=4 SV=1
------------------------------EDVARRIKKSKNIVVMAGAGISTPSGIPDFRSPGGLYDNLYPEAIFDIDFFRKNPKP---FFTLAKELYP
SGKYRPNYVHYFVRMLYEK-GLLLRMYTQNIDGLERLAGIDKLVEAHGTFTRCTCTKCGYQHEGEDVIDKIPRCMRCT--GVVKPNIVFFGEDLKRFFYY
MKDMPLCDLLIVMGTSLEVYPFAGIVDSVRP-FVPRLLINREVVGFSRHNDLAVTGDLVECVQKFA-------------
>tr|M7U5Z2|M7U5Z2_BOTF1 Putative chromatin regulatory protein sir2 protein OS=Botryotinia fuckeliana (strain BcDW1) GN=BcDW1_2296 PE=4 SV=1
------------------------------DDAVELIRGAKKIIVITGAGISTSLGIPDFRSANGLYAQNDPQEIFNIEKFKEDPSIFFGVAK---VILP
-EIRRFSPTHQFIALLQAH-GKLLTNYTQNIDNIESMAGIDKIIHCHGSFATATCQVCGHKVKGDDDIKHIPRCKMCPPSGIMKPDITFFGENLPVFDRL
KHDRDQVDLVITIGTSLKVAPVSEVVPYLP-SNVPQIQINRDPVGH-LAFDIDLVGECDVVVSKLCKELDWDISHEMV-
>tr|W9C379|W9C379_9HELO Chromatin regulatory protein Sir2 OS=Sclerotinia borealis F-4157 GN=SBOR_8364 PE=4 SV=1
------------------------------DDAIELIRNAKKIIVLTGAGISTSLGIPDFRSANGLYAQTDPQDVFNIELFQEDPTIFFGIAK---DILP
-SLGRFSPTHKFIWLLQNK-GKLLTNYTQNIDDIESAAGIENLIQCHGSFATATCQKCGHKVKGDDEIKHIPRCRKCILAGIMKPDITFFGEQLPTFDRL
KRDRDQVDLVITIGTSLKVAPVSEVVPYLP-SHVPQIQINRDPVRH-VDFDIDLLGDCDIVVVELCKALGWNLEHEMI-
>tr|A7EMW8|A7EMW8_SCLS1 Putative uncharacterized protein OS=Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1) GN=SS1G_06667 PE=4 SV=1
------------------------------DDAIVLIKNAKKIIVITGAGISTSLGIPDFRSANGLYAQSDPQEVFNIDLFREDPTIFFQIAK---NILP
-SVVRFSPTHQFIKVLQDK-GKLLTNYTQNIDGIESAAGIENVIQCHGSFATATCQQCSTQVKGTPEIKNIPRCKVCKIPGIMKPDITFFGESLPKFDRL
KHDRDQVDLVITIGTSLKVAPVSEVVPYLP-SNVPQIQINRDPVSH-VEFDIDLLGECDVVVSELSKALGWSLDHEMI-
>tr|A0A0D2UH90|A0A0D2UH90_CAPO3 SIR2 family histone deacetylase OS=Capsaspora owczarzaki (strain ATCC 30864) GN=CAOG_005116 PE=4 SV=1
--------------------LEDVNTI---DDVVRLIKTSKNIVILSGAGISVSCGIPDFRSKDGVYARPDPHAMFDIEFFRSDPRPFFQFAKELF----
PGNFLPAASHYFISMLDQK-GQLLRNYTQNIDTLEHVAGVKNMLQCHGSFATASCMVCHAQSDGMEQVQIVPRCSQCGPQAIIKPDIVFFGEQLPAFDSL
MQDRQKVDLLIVMGSSLKVQPVAHIPGCFD-ESVPRILINREPLPR-VAFDVELLGNCDQIVQELCARLGPEY------
>tr|A0A0G4HR52|A0A0G4HR52_9ALVE Uncharacterized protein OS=Chromera velia CCMP2878 GN=Cvel_30476 PE=4 SV=1
-------------------------------------SNHSRIVVISGAGCSTESGLPDYRGPLGSYRKHKP---IKHDEFVKQEPARKRYWAR--SMMG
FSSARPNEAHVSIARLEVA-GLVDGVITQNVDGLHQKAGSSQVVDLHGRTDRVLCLNCGWKSSWQQDLFQVPVCSRCG--GMVKPDVTFFGDNVRIREEA
YRLVDEAGALLVVGTSLEVFSAYRFVLRAGERGLPVGVVNLGPTRAEREVKMRAEGPCGLLLSQATGRLE---------
>tr|J3NPL1|J3NPL1_GAGT3 Uncharacterized protein OS=Gaeumannomyces graminis var. tritici (strain R3-111a-1) GN=GGTG_03219 PE=4 SV=1
-------------------------------------GDVRRIIVLTGAGISTAAGIPDFRSPTGLYSNLHAEAVFDIEYFRKHPEP---FYYLAKELY-
PGNFYPTLSHAFIALLHKK-GLLHVDFTQNIDCLERHAGVSRIVEAHGSFATQRCIDCRAEFDGDRHVGVVPHCDECN--GLVKPDIVFFGEPLPGFREN
SHKVVMTDAVIIIGTSLSVYPFAGLADMVP-AGVPRLLLNKQRVHGDRSDDVVEIGPCDDGVRRLADLL----------
>tr|G7PNM6|G7PNM6_MACFA NAD-dependent deacetylase sirtuin-3, mitochondrial (Fragment) OS=Macaca fascicularis GN=EGM_05241 PE=4 SV=1
------------------------------QDVAELIRACQRVVAMVGAGISTPSGIPDFRSPSGLYSNLYPEAIFELPFFFHNPKP---FFTLAKELY-
PGNYKPNITHYFLRLLHDK-GLLLRLYTQNIDGLERVSGISKLVEAHGTFASATCTVCRRPFPGEDDVDRVPRCPVCT--GVVKPDIVFFGEPLPRFLLH
VVDFPMADLLLILGTSLEVEPFASLTEAVR-SSVPRLLINRDLVGWRRGRDVAQLGDVVHSVERLVEL-----------
>tr|A0A085M2R2|A0A085M2R2_9BILA Uncharacterized protein OS=Trichuris suis GN=M513_07558 PE=4 SV=1
------------------------------PEVAQLIMRSKRIVVVAGAGISVSCGVPDFRGIGGLYRMYNPEQVFSIDFFDVHPEL---FYEVAKELY-
PAGLRPSLTHRFFALLEKK-NKLLRMYTQNVDTLEEKAGIENIIYCHGSFATASCRTCGVQVEGAILAQKVPHCKRCKAVSVMKPDITFFGESLPFFDYI
SGDMERLDLLLVVGTSLKVNPVNLIPDSVP-LNVPRVLINCDKVE--KTFDIDIICRCDDAIRQLMEMMGE--------
>tr|J9IKI8|J9IKI8_9SPIT Histone deacetylase 14 OS=Oxytricha trifallax GN=OXYTRI_03232 PE=4 SV=1
------------------------------KDLIDGLVKFKRIVVLTGAGISVSAGIPDFRSPGGVYANLFPEAIFTLDYFKINPEAFYTFCQSFD----
MDTFKPTPTHYFLVLLDKM-GVLHMNFTQNIDALEEKAGMEKLLQAHGTVKGARCALCQRDMDEQEHIGVVYRCSECN--GPVKPNIVLFGEAPKDFFKK
YQKIQDCDLVLVMGTALAVSPFNTLVSSAPK-DIPKVLINRENTVEDGDDKLFLQGDCDEIIKKIIKDC----------
>tr|A0A078B2P2|A0A078B2P2_STYLE Nad-dependent deacetylase sirtuin-2 OS=Stylonychia lemnae GN=Contig18101.g19241 PE=4 SV=1
------------------------------RDLIDGLTQFKKIVIMTGAGISVSAGIPDFRSPGGVYANLFPEAIFTLPYFIENPEAFYTFCQEFD----
LDIYKPTPTHLFITLLDQM-GVLLMNYTQNIDNLEEKAGLNKLLQAHGSASGAKCAICKMDMDEQEQIAEVYRCLNCK--GPVKPNIVLFGEAPSDFFKK
SQMISSCDLLLIMGTALAVSPFNSLVSSAPK-NTPKVLINRENLAQDDDDKLFLEGNCDDIIQKIVKDC----------
>tr|A0A0B2URY5|A0A0B2URY5_TOXCA NAD-dependent protein deacetylase sirtuin-2 OS=Toxocara canis GN=sirt2 PE=4 SV=1
------------------------------------QGKAKNIIFMVGAGISTSAGIPDFRSPTGLYDSPDPMCIFDIGYFSRNPEP---FYRVAKKLFP
-TTLKPTPCHYFIRMMDEK-GLLLRCFTQNIDSLEFVANIDKFVTAHGSHRTSTCLKCREKYDWITEICVVARCDKCN--GIVKPDIVFFGENLPFFNRS
ISDFPKCDLLIIMGTSLVVQPFASLINEVA-DDVPRLLINLTEAGRDNYRDVFWQGTCDDGVFLLAELL----------
>tr|F1KVX2|F1KVX2_ASCSU NAD-dependent deacetylase sirtuin-2 OS=Ascaris suum PE=2 SV=1
------------------------------------QGKAKNIIFMVGAGISTSAGIPDFRSPTGLYENPDPMCIFEINYFAKHPEP---FYILAKKLFP
-STLKPTPCHYFIRMMDEK-GLLLRCYTQNIDSLEFVANIEKLVTAHGSHHTSTCLRCHEKYDWITEISTVARCEKCN--GVVKPDIVFFGENLPFFNCA
IADFPKCDLLIIMGTSLVVQPFAGMVNEVA-GDVPRLLINLTEAGRDNHRDVFWQGTCDEGALLLAELL----------
>tr|E5RZ24|E5RZ24_TRISP NAD-dependent deacetylase SIR2-like protein OS=Trichinella spiralis GN=Tsp_07421 PE=4 SV=1
------------------------------ELAVRLIQQSRKIMVLVGAGMSVSCGISDFRSANGIYARPDPTAVFDIDYFYENPKPFFSFVKELF----
PGNYRPSLSHRFLKCLEDE-GKLLRVYTQNVDTLEKQVGLHKVVYCHGSFDTATCMECGFKVDCEEAVEAIPTCRNCAQHGVMKPDIVFFGESLPFYESV
AADQSQVDLLIVIGSSLKVRPVSLIPRALQ-ASVPLILINRETLN--LFFDVELLGDSDVICEELCSRLSESF------
>tr|M2XTW5|M2XTW5_GALSU NAD-dependent histone deacetylase SIR2 OS=Galdieria sulphuraria GN=Gasu_53280 PE=4 SV=1
------------------------------QDLARIIKQASHILVVSGAGISVSCGIPDFRSAGGIYERFDPQEIFDLNVFKESPELFYSFAKE---IIP
RESTEPSLSHRFIRDLECH-QKLLRNYAQNIDGLESIAGIDRVVYCHGSFSAAHCLRCNAHYSLDDDIVRVPYCSFCGNPNIIKPDIVFFGEALDFFDCF
ESDRETADLLLVIGTSLQVAPVSKIPFCIS-AEIPQVLINLEPVGPSDWFDLELIGPCDVIIERLYQLLG---------
>tr|A0A067N447|A0A067N447_9HOMO Uncharacterized protein OS=Botryobasidium botryosum FD-172 SS1 GN=BOTBODRAFT_28366 PE=4 SV=1
--------------------------INTISDVLSLLRASKNIVVLSGAGISVSCGIPDFRSPDGLYARYDPQDMFSITYFKEKPYVFYSFAH---KIYS
-SDFQPSPSHYFLKSLEDQ-NKLLRNYTQNIDTLEMKAGVRRVIQCHGSFATASCVECGYQVNGSEHSQQIPVCPMCAEPYIMKPDITFFGEQLDEFDLL
VEDKDKVDLLIIIGTSLKVSPVSEIPVEIP-HSVPQILINKTPVSH-ANPDVIMLGDADYIIEYLCRELRWG-------
>tr|A0A0L8FRB6|A0A0L8FRB6_OCTBM Uncharacterized protein OS=Octopus bimaculoides GN=OCBIM_22010267mg PE=4 SV=1
-----------------RQKLNYVNTI---DDVVHLLKTSQKIMVLTGAGVSVSCGIPDFRSRNGIYARPDPQAMFDIHYFRNDPRPFFKFAKE---IY-
PGQFEPSKCHKFIKLIEDH-NRLLHNYTQNIDTLEQQAGIKKVIQCHGSFATATCMNCSSKVSAREDIFVIPRCQVCTS-AIMKPDIVFFGENLPHFHQM
AEDKEQCDLLIVIGSSMKVRPVALIPNYIPA-HVPQILINREPLKH-MTFDVELLGDGDIIVNDLCKRLGEGWKE----
>tr|A0A0R3SJ57|A0A0R3SJ57_HYMDI Uncharacterized protein OS=Hymenolepis diminuta PE=4 SV=1
------------------------------QAAIDLLKEKSKILVLTGAGISVSCGIPDFRSRNGIYARFNPQDMFDLKFFKSNPNPFYTFAKE---LF-
PGQFKPSYTHRFIRLLEKK-SKLLRNYTQNIDTLEEIAGISKIIHCHGSFSTASCLTCYHQLPGEELRPEVGECAPLL--GLMKPDIVFFSESLPEFYTL
DKDVRDVDLVLVMGSSLKVRPVSHIPNSVP-HHVPQILINREPLS-NHQFDIELLGDCDVVVEYLCKELGW--------
>tr|A0A061BI19|A0A061BI19_CYBFA CYFA0S33e00210g1_1 OS=Cyberlindnera fabianii GN=CYFA0S_33e00210g PE=4 SV=1
----------------TRSRLPDFNKV---SQAVEAIQNANKILVLTGAGISTSLGIPDFRSSKGIYAMEDPQEVFDLQTFKADPEI---FYQVAHMVL-
PPENVWTATHQFIKLLSDK-GKLLRNYTQNIDNIEATVGIEQYIQCHGSFATAICRTCKREIEGHKRKQEMPVCSRCYEMGIMKPGITFFGEDLPFHANI
ENDCRECDLVVCIGTSLKVSPVNDIVNLVGE-DVPQILINKDDIT-HSEFDVTLLGLCDEVVTFLSDELN---------
>tr|A0A0H5C832|A0A0H5C832_CYBJA SIR2 protein OS=Cyberlindnera jadinii GN=SIR2 PE=4 SV=1
----------------NRLRITDMNTV---AQAVDAIKSAKNIIVLTGAGISTSLGIPDFRSAKGIYSLDDPQQVFDLETFRYDPEI---FYKVAHMIL-
PPEGKWTPTHAFIKELSNH-NKLLRNYTQNIDNLEASVGIDKYIQCHGSFAHATCRTCGYKVDGTKRAQQLPVCARCFTLGIMKPDITFFGEDLPFYENL
PDDIRKCDLLICIGTSLKVAPVNEIVNKIRP-EVPQILINKDDIS-HAEFDISLLGYCDEVTVYLTNKLG---------
>tr|A0A0L1HJ26|A0A0L1HJ26_9PLEO Nad-dependent deacetylase sirtuin-2 OS=Stemphylium lycopersici GN=TW65_87006 PE=4 SV=1
--------------------------------------LAQKIVVMTGAGISTSAGIPDFRSPTGLYANLYPEAVFDIGFFRNNPEP---FYTLAQELY-
PGKFRPTITHSFITLLHQK-GLLLKLFTQNIDCLEREAGVDKIIEAHGSFATQCCIDCKKPYPKERHSKSVPHCVDCN--GLVKPEIVFFGEQLPAFFDN
RDLPAQADLCIVMGTSLSVHPFASLPQLCED-TTPRLLINSEKVGDGARDDVLLLEDCDGGVRKLAE------------
>tr|A0A0D2DRB3|A0A0D2DRB3_9EURO Uncharacterized protein OS=Exophiala oligosperma GN=PV06_03835 PE=4 SV=1
------------------------------QEIADVLARSHKVLLVTGAGISTSCGIPDFRSKDGLYNIIPEQNLFDSRVF-QNATLFYQFIASLRQKIR
DEVQSTSSTHKFIRVLRD-GGRLVRCYTQNIDGLEGREGLCEVVQLHGDLERLRCSMCATQFEWTDEETAAPSCQQCYSVGSLRPNIVLYGEDHPLLTPL
FDAGSQPEVLVIMGTSLKVFGLQKIVREFHSSQGRVIFVNRTKPAWDGIIDDFVAMDCDDWIHDLK-------------
>tr|L8G1J0|L8G1J0_PSED2 Uncharacterized protein OS=Pseudogymnoascus destructans (strain ATCC MYA-4855 / 20631-21) GN=GMDG_02329 PE=4 SV=1
------------------------------QEIADALSKSKKVVVITGAGISTNCGIPDFRSENGLYTLIQAQELFDSIIW-TDKSIFYTFISSLRQKIL
KDVTSTTDTHKFIRALRD-GGRLVRNYTQNIDMLERREGLVEVVHLHGSLDFLRCGLCARLANWEDDDREAPECPWCSEVGRLRPDIVLYGEEHPLVGPL
HDLSLSPDMLLILGTSMRVHGLKVMVREFHGRGGSVVFVNQTKPPWGDVIDYWVEWDCDAWVADLK-------------
>tr|A0A0D1X7Q7|A0A0D1X7Q7_9EURO Uncharacterized protein OS=Exophiala mesophila GN=PV10_01600 PE=4 SV=1
------------------------------QEIADILSGSHKILLVTGAGISTSCGIPDFRSKDGLYNIIPDQDLFHSRVF-HNATIFYQFIASLREKIK
NEVQATSSVHKFVRVLRD-GGRLMRCYTQNIDGLEAREGLCEVVQLHGDLDRLRCTVCAAQFEWTEEETAAPSCQKCKTTGSLRPNIVLYGEEHPLLTPL
FDASCQPEVMVIMGTSLKVFGLQKMVREFHGQKGRVIFVNRTRPAWDGIIDDFVAMDCDDWVEDLK-------------
>tr|W2RLR3|W2RLR3_9EURO Uncharacterized protein OS=Cyphellophora europaea CBS 101466 GN=HMPREF1541_08952 PE=4 SV=1
------------------------------QDIADTIASSHKILIVTGAGISTSIGIPDFRSKDGLYNLIPEQDLFDSRVF-NSATIFYRFIASLREKIH
DDVKETSATHKFIRVLRD-GGRLMRCYTQNIDGLEAREGLCEVVQLHGDLDTLRCSVCATQWTWTENETFAPRCKKCARVGSLRPNIVLYGEDHPLLSPF
YDAGSQPDVLIIMGTSLKVFGLQKIIREFHAQKGKVIFVNRTKPAWDNFIDYFIPMDCDDWIDDLK-------------
>tr|A0A094ERM6|A0A094ERM6_9PEZI Uncharacterized protein OS=Pseudogymnoascus pannorum VKM F-4515 (FW-2607) GN=V496_09824 PE=4 SV=1
-------------------------------------------MCLRP---LGSLQTAAYLSENGLYTLIQAQELFDSIIW-TDRSIFYTFISSLRQKIL
NDVKSTTDTHKFIRALRD-GGRLVRNYTQNIDMLETREGLVEVVHLHGSLHSLRCSLCARLASWEDEDREGPECPWCSEVGRLRPDIVLYGEEHPLVGPL
HDLSLNPEMLLILGTSMRVHGLKVMVREFHGRGGSVVFVNQTKPPWGDVIDYWVEWDCDAWVADLK-------------
>tr|A0A0D2AJH8|A0A0D2AJH8_9EURO Uncharacterized protein OS=Cladophialophora immunda GN=PV07_10678 PE=4 SV=1
------------------------------QEIADCLANSHKVLLVTGAGISTSCGIPDFRSKDGLYNMIPGQELFDSRVF-QHATIFYQFIASLRQKIR
DEVRSTSSVHKFVRVLRD-GGRLMRCYTQNIDGLELREGLCEVVQLHGDLEKLRCTMCSTQYPWTDEQTAAADCPKCRDVGALRPNIVLYGEDHPLLTPL
FDASCQPDVLIIMGTSLKVFGLQKIVREFHSHKGRVIFVNRTRPAWDGIIDDFVAMDCDDWVDDLK-------------
>tr|W9YH89|W9YH89_9EURO Uncharacterized protein OS=Capronia epimyces CBS 606.96 GN=A1O3_02089 PE=4 SV=1
------------------------------QEIADLLVGSHKILLVTGAGISTSCGIPDFRSKDGLYNMIPEQDLFDSRVF-QNATMFYQFIASLRQKIR
DEVCSTSSVHKFVRVLRD-GGRLMRCYTQNIDGLEGREGLCEVVQLHGDLEKLRCTMCATQFEWTDEETAAPSCPKCKATGSLRPNIVLYGEDHPLLTPL
FDAGSQPEVMIIMGTSLKVFGLQKIVREFHARKGRVIFVNRTRPAWEGIIDDFVAMDCDDWVEDLK-------------
>tr|V9DNK7|V9DNK7_9EURO Uncharacterized protein OS=Cladophialophora carrionii CBS 160.54 GN=G647_00327 PE=4 SV=1
------------------------------QEIADTLAGSHKVLVVTGAGISTSCGIPDFRSKDGLYNMIPSQGLFDSRVF-QNATVFYQFIASMRHKIR
DEVRSTSSVHKFIRVLRD-GGRLMRCYTQNIDGLEAREGLCEVVQLHGDLDKLRCTMCSTQYEWRDEETAAPSCPKCKEVGSLRPNIVLYGEDHPLLTPL
FDAGCRPEVLVIMGTSLKVFGLQKIVREFHSHKGRVIFVNRTRPAWEGIIDDFVAMDCDDWVDDLK-------------
>tr|A0A0N1P069|A0A0N1P069_9EURO NAD-dependent histone deacetylase HST3 OS=Phialophora attae GN=AB675_5639 PE=4 SV=1
------------------------------QDIADIIAASHKVLVVTGAGISTSIGIPDFRSKDGLYNLIPESDLFDSRVF-QDATMFYRFIASLREKIY
DEVKDTSGTHKFIKTLRD-GGRLMRCYTQNIDCLESREGLCEVVQLHGELDTLRCSVCSTQWTWTENETFAPRCKKCAKVGSLRPNIVLYGEDHPLLSPF
YDASCQPDVLIIMGTSLKVFGLQKIIREFHGQKGKVIFVNRTRPAWDSFIDYFVPMDCDDWVIDLR-------------
>tr|A0A0D1YGZ6|A0A0D1YGZ6_9EURO Uncharacterized protein OS=Exophiala sideris GN=PV11_07771 PE=4 SV=1
------------------------------QEVADILAGSHKVLLVTGAGISTSCGIPDFRSKDGLYNIIPEQDLFDSRVF-QNATMFYQFIASLRQRIR
DEVRSTSTTHKFIRVLRD-GGRLMRCYTQNIDGLEAREGLCEVVQLHGDLEKLRCTMCAKQMDWTDEETAAPSCQSCRVVGSLRPNIVLYGEDHPLLTPL
FDAICQPEVLVIMGTSLKVFGLQKIVREFHSQKGRVIFVNRTRPAWDGVIDDFVAMDCDEWVEDVR-------------
>tr|A0A0D2I897|A0A0D2I897_9EURO Rhinocladiella mackenziei CBS 650.93 unplaced genomic scaffold supercont1.6, whole genome shotgun sequence OS=Rhinocladiella ma
------------------------------QEIADTLVRSHKILLITGAGISTSCGIPDFRSKDGLYNIIPEQELFDSRVF-HNPTIFYQFIAHLREKIR
GEVRSTSSVHKFVRVLRD-GGRLMRCYTQNIDGLESREGLCEVVQLHGDLEKLRCTMCSTPFAWTDAETAAPKCPQCQTVGSLRPNIVLYGEDHPLLTPL
FDAGCQPEVMIIMGTSLKVFGLQKIVREFHAHKGRVIFVNRTRPAWEGIIDDFVAMDCDDWVEDLK-------------
>tr|U1GFH5|U1GFH5_ENDPU Uncharacterized protein OS=Endocarpon pusillum (strain Z07020 / HMAS-L-300199) GN=EPUS_07352 PE=4 SV=1
------------------------------QDIADRMVKSHKILLITGAGISTSCGIPDFRSKDGLYNLIPEQELFDASVW-KNAEVFYRFIASLRQKIR
DEVKETSPTHKFIRTLRD-GGRLMRCYTQNIDGLERRENLCEVVPLHGDLEVLRCTLCLERSPWTEEMTLAPECSVCARVGSLRPNIVLYGEEHPLLAPL
FDLGSGPEILIIMGTSLKVHGLQKVVREFHARKGKVIFVNRTKPAWENVIDSYVAMDCDDWVMDLK-------------
>tr|A0A072PDY5|A0A072PDY5_9EURO Uncharacterized protein OS=Exophiala aquamarina CBS 119918 GN=A1O9_05435 PE=4 SV=1
------------------------------QDIADILASSHKVIVVTGAGISTSCGIPDFRSKDGLYNIIPEQDLFDSRVF-QDVRVFYQFIASLRQKIR
DEVRATSSVHKFLRVLRD-GGRLMRCYTQNIDGLETREGLCEVVQLHGDLQKLRCTMCAVQYEWTDEETAAPNCQKCKAVGCLRPNIVLYGEDHPLLTPL
FDASCQPEVMIIMGTSLKVFGLQKMVREFHAHKGKVVFVNRTRPAWEGTIDDFVCMDCDDWVDDLR-------------
>tr|U4LQF5|U4LQF5_PYROM Similar to NAD-dependent histone deacetylase HST3 acc. no. Q5A1W9 OS=Pyronema omphalodes (strain CBS 100304) GN=PCON_02958 PE=4
------------------------------QEIADNVARSKKIVVVTGAGISTNCGIPDFRSTDGLYNLVKSQ-LFDAVLW-NDPSLFYTFLANLRREVI
-AVPDTTAVHKFIRTLAE-TGRLLRCYTQNIDGLEEREGLCQVVQLHGDLRSLRCTNCQLLTEYTASSVEAPVCEACEAVGFLRPNIVLYGEEHPQVGAI
ADIKAAPDMMIILGTSLKVHGLKIIVRQFHAKGGKVIFVNNTPPSWEGVIDEYVEMDCDKWVADVR-------------
>tr|A0A0L0VZS8|A0A0L0VZS8_9BASI Uncharacterized protein OS=Puccinia striiformis f. sp. tritici PST-78 GN=PSTG_02258 PE=4 SV=1
------------------------------NDLAILIGRVENVIIMAGAGISTSAGIPDFRSPTGIYANYYPEAIFDIDYFKENPAP---FYTLAK-ELN
PKNFQPTKTHQFFKLLEIK-NKLKKCFTQNIDTLERLAGLSLIVEAHGSFATSRCIECHAEMSDNEFMPLVVKCPACLKTALVKPDIVFFGEQLPKFFDS
LSDFQEADLLIVLGTSLQVQPFASLISTVPI-NCPRLLINLEAVGEIGIRDVLVLGNTDDVVEELCDLLG---------
>tr|E3KY50|E3KY50_PUCGT Putative uncharacterized protein OS=Puccinia graminis f. sp. tritici (strain CRL 75-36-700-3 / race SCCL) GN=PGTG_15092 PE=4 SV
------------------------------DDVATLIGRVENIIIMAGAGISTSAGIPDFRSPTGIYANYYPEAIFDIDYFKKNPAP---FYTLAK-ELN
PKNYRPTKTHQFFKLLETK-KKLKRCFTQNIDTLERLAGLSLIVEAHGSFATNRCIVCRAEMSDDRFMPLVVKCPECIGTALVKPDIVFFGEQLPKFFGS
LTDFQEADLLIVLGTSLQVQPFASLISTVPI-NCPRLLINLEKVGDIGIRDVLVLGTTDDGVEELCDLLG---------
>tr|A0A0C7N0R9|A0A0C7N0R9_9SACH LALA0S09e01376g1_1 OS=Lachancea lanzarotensis GN=LALA0_S09e01376g PE=4 SV=1
----------------------GCDSDFVQLQAIKQINRARRVLVLTGAGISCNAGIPDFRSSSGLYELYSGQEMFDISLFREENKVFASFMEKLYSSA-
-RVAQPTKTHRFIAHLKNR-GKLLRCYTQNIDGLEETLGLLDVVQLHGDLNKLSCTQCFATCDWNRMLGQLPNCPRCQDIGLLRPNIVLYGENHPFITQG
LIDIGRPDLFFIMGTSLKVDGVKKLVRNIHERNGLVILINKTKINWHGIIDYQILSDCDDWVDHLQE------------
>tr|A0A0P1KWS0|A0A0P1KWS0_9SACH LAQU0S11e03356g1_1 OS=Lachancea quebecensis GN=LAQU0_S11e03356g PE=4 SV=1
----------------------PLEEDIELIKQVKQISKSRKILVLTGAGISCNAGIPDFRSSSGCYELYSGQEMFDISLFREEQKIFATFMEKLYSSA-
-RIAQPTRTHRFIAHLKNR-GKLLRCYTQNIDGLEENLGLLDVVQLHGDLNRLSCTQCFKTFNWNRGLGQLPSCPRCEDIGLLRPNIVLYGENHPFITQG
LLDIGRPDLFFIMGTSLKVDGVKKLVRNFHERNGLVILINKTRINWHGIIDYQILSDCDAWVDHLKD------------
>tr|L2GMI6|L2GMI6_VITCO Uncharacterized protein OS=Vittaforma corneae (strain ATCC 50505) GN=VICG_00942 PE=4 SV=1
----------------------NIDSDFLL---NKSLLDHKKCVFVVGAGISVASGIPDFRSPTGIFASLNGRQLFTYNFGIKEGSIYLKYISSLKRLC-
-DSSHPNVTHHFLANFPK-----SRTYTQNIDGLEESAGMTKGVYLHGNLSFLVCQYCGFRKKFNEADGDEIACSECSEVGVLHPGIIHYQQIHPFISKI
CKDM-DCDLLIVIGTSLAVEGVKKLVKMFAS-EGKRILVNLTK-EWGDYFDYFYEGDCAEFARTVGS------------
>tr|I1FXD0|I1FXD0_AMPQE Uncharacterized protein OS=Amphimedon queenslandica GN=LOC100638465 PE=4 SV=1
--------------------------EFTIERLAHDLAKFKKIIVMTGAGISTSSGIPDFRTPTGLYDNLEPTAIFDITYFSRNPKPF---FTLAQELY-
PGKYSPNSVHYFIKLLQEK-GFLLRNYTQNIDGLERLAGISKLVEAHGSFSTASCTLCHAKHNSDDAISTIPKCKHCS--GVVKPDVVFFGEDLPQRFHA
LVDFAHCDLLIVMGTSLEVEPFASLATSTR-FDTPRVLINRELVGFKRPMDLSLTGDLTDQISELVR------------
>tr|K2SEV8|K2SEV8_MACPH Cytochrome P450 OS=Macrophomina phaseolina (strain MS6) GN=MPH_07426 PE=4 SV=1
--------------------------------------RAKKVVVMTGAGISTSAGIPDFRSPTGLYANLYAEAVFDISYFRNNPLP---FYTLAQELY-
PGKYRPTITHSFIRLLYEK-GILLKLFTQNIDCLEREAGVDMIVEAHGSFAEQACIECGASYPDDKHIMEPPRCEQCG--GLVKPKIVFFGEQLPSFFDN
RDKPAEADLCIVMGTSLTVQPFASLPNFVR-DGCPRLLINKEQVGSIRGDDVMLLDDCDTGVRRLAEA-----------
>tr|A0A0G2G882|A0A0G2G882_9PEZI Putative cytochrome p450 OS=Diplodia seriata GN=UCDDS831_g09059 PE=4 SV=1
--------------------------------------GAKRVVFMVGAGISTSAGIPDFRSPTGLYANLYAEAVFDISYFRNNPLP---FYTLAHELY-
PGKYRPTITHSFMRLVHDK-GLLHKLFTQNIDCLEREAGVDAIVEAHGSFAGQACIDCGQDYPDDAHIMEPPRCRRCD--GLVKPKIVFFGEQLPAFFDA
RDAPAEADLCVVMGTSLSVQPFASLPNFVG-DACPRVLINKEQVGSLRPDDVLLLDDCDAGVRRLADA-----------
>tr|F4NYJ7|F4NYJ7_BATDJ Putative uncharacterized protein OS=Batrachochytrium dendrobatidis (strain JAM81 / FGSC 10211) GN=BATDEDRAFT_18937 PE=4 SV=1
-----------------KLCILKDSSI---ESFVEYLKECSKVIVMTGAGISTSAGIPDFRTPTGLYDNLYPEAIFDIAYFRQKPQA---FYTLARELF-
PGNYNPTPTHHFIKKLADN-CMLLRNYTQNIDMLERMVGVDFLVEAHGSFHLARCVDCGKTYTIQEFITPIPRC-ECG--GLIKPDIVFFGESLPFYDLL
VDDFQRCDALIVMGTSLQVQPFAGLVNQVGP-LVPRLLVNKDM------------------------------------
>tr|W5LLL0|W5LLL0_ASTMX Uncharacterized protein OS=Astyanax mexicanus PE=4 SV=1
----------------------------------MKLGRLRNVVVVAGAGISTASGIPDFRTPTGLYANYYPEAVFNIDYFSDDPRP---FFSLAKELY-
PGRHRPNYIHYFIRMLHQK-GLLLRMYTQNIDGLEKMCGIDKLVEAHGSFATASCHLCYTPFPSEEAKDNIPTCSFCS--ATVKPSVVFFGEDLPTYFQH
AQDFPKADLLIIMGTSLQIEPFASLVNTVKS-TVPRLLLNRHAVGFERRRDYLELGDLVHSVRKLAEIL----------
>tr|F1QVT1|F1QVT1_DANRE Uncharacterized protein OS=Danio rerio GN=si:dkey-103i16.6 PE=4 SV=2
----------------------------------MKLGRVRNIVVVAGAGISTASGIPDFRTPTGLYANYYPEAVFNIDYFSDNPHP---FFSLAKELY-
PGHHRPNYVHYFIRMLHQK-GLLLRMYTQNIDGLEKLCGIDKLVEAHGSFATAACHLCYTPYPAEEAKGSVPICTFCA--GAVKPNVVFFGEDLPKYFQH
AEDFPKADLLIIMGTSLKIEPFASLINTVKS-TVPRLLLNRDAVGFERRADYMELGDLSESVRKLAEIL----------
>tr|A0A095ETF2|A0A095ETF2_CRYGA NAD-dependent histone deacetylase SIR2 OS=Cryptococcus gattii R265 GN=CNBG_5794 PE=4 SV=1
---------------RRRERLQDISSL---DDAVSLLARAKKIIVLSGAGISTSCGIPDFRSSTGLYAQDDPQQMFDIRYFREKPEVFYSFAKQ---IY-
PSNFVPSPCHRWIKMLEDR-GVLLRNYTQNIDTLENLAGVERVLQCHGSFKTASCLRCKQQVPGRTYSQEIPYCGSCSEPGIIKPDITFFGQALDEFDEL
FKDREEVDLLVVIGTSLKVAPVSEVLTHIP-HSVPQIFINLTPVYH-VHPDISLLGDADSIVTYLSDRLG---------
>tr|A0A0N4U3H0|A0A0N4U3H0_DRAME Uncharacterized protein OS=Dracunculus medinensis PE=4 SV=1
---------------------------------FKQFSRSKKIIIVTGAGISVSSGIPDFRSKGGIYSRLHPSSMFEMDYFKLNPRPFFEFVRE---IF-
PGQFKPTLCHRFIKALEIE-NKLLRNYTQNIDTLENLAEIRRVVFCHGSFKSATCLNCHECVPIDELIGEIAMCKKCDASGVLKPDIVFFGEDLEEFNRL
NEDKDEADLLVVIGSSLKVQPVALLPYHVKK-DVPQILINRERLPH-YYADIELLGNSDDIITQLILALG---------
>tr|A0A060WLS5|A0A060WLS5_ONCMY Uncharacterized protein OS=Oncorhynchus mykiss GN=GSONMT00002991001 PE=4 SV=1
----------------------------------VKLGRCKNVVVVAGAGISTASGIPDFRTPTGLYANYYPEAIFNIEYFSNDPRP---FFSLAKELY-
PGSHRPNYIHYFIHMLHLK-GLLLRMYTQNIDGLEKISGIEKLVEAHGSFATASCHLCYTPFPAQEASDKVPVCTFCQ--ATVKPDIVFFGEDLPKYFLH
SKDFPKADLLIIMGTSLQIEPFASLVNTVR-STVPRLLLNRDAVGPQRRGDFIELGDLVDTVRRFGEF-----------
>tr|A0A010RW09|A0A010RW09_9PEZI ATP synthase F0 OS=Colletotrichum fioriniae PJ7 GN=CFIO01_09784 PE=4 SV=1
-------------------------------------GDVKKIAVMTGAGISTAAGIPDFRSPTGLYANLYAEAVFDISYFRKHPEP---FYYLAKELY-
PGKFHPTVSHAFIALLAKK-GLLQMNFTQNIDCLERRAGVDKIIEAHGSFATQRCIECKDTFPADRQDENVPKCDSCG--GLVKPDIVFFGEALPAFRDN
THLPAMADLIVVMGTSLSVYPFAGLAEASK-SGVPRLLLNRERVGQGRRADVVELGTCDAGVRKLAAL-----------
>tr|A0A0A9YER2|A0A0A9YER2_LYGHE NAD-dependent deacetylase sirtuin-2 OS=Lygus hesperus GN=sirt2_1 PE=4 SV=1
--------------------------------------EIKKVVTLSGAGISTAAGIPDFRSPDGLYDKLYAQAVFERKYFDKNPKP---FFALLKETL-
CKEYKPTIAHYFIKLLEEK-GLLLRHFTQNVDGLERLAGVTRMIEAHGTVYTSRCMKCKTEYDWLRDQKSIPYCQECQ--GIVKPNVILFGETLDQFSAV
NKDLPRCDLLIVMGTSLVVEPFASAVKKVHS-SCSRIIINNIPVGEDSWRDIFIQGSCDDGVLHLAKL-----------
>tr|A0A058ZD17|A0A058ZD17_9EUKA Uncharacterized protein OS=Fonticula alba GN=H696_01250 PE=4 SV=1
--------------------------------VVDIIRRARRICVLTGAGISVSSGIPDFRSSGGVYSLYTPEAIFDLNYFRTNPGPFFAFASEMFPGMT
--KYHPTPTHYFIRLLQDH-GQLERNYAQNIDGLELEAGITKLVQCHGSFATATCQLCARKYQADDIVHIIPRCE-CDENSVIKPDIIFFSESLPTFDDA
NQDSDHIDAMIVIGTSLQVSPVSLVPSLLP-RGVPRILINRELVST-ATFDAEILGDCDKVIVELCRRLG---------
>tr|A0A060VRM4|A0A060VRM4_ONCMY Uncharacterized protein OS=Oncorhynchus mykiss GN=GSONMT00072728001 PE=4 SV=1
------------------------------EALAQLIRESQYLVVHSGAGISTSSGIPDFRGPKGVWTMEERGE---------SPH----FDT----T--
FEEARPSLTHMALLGLQRA-SYLKYLISQNVDGIHVRSGFNLLSELHGNMFVEECGKCGKQYVREKVIGTGKYCESCR--GKLISTILDWEEALPDLNRA
EEASRRADLALTLGTSLQIKPSGDLPLFTKRKGGKVVIVNLQPTKHDKHAHLRINGYVDEVMSQLMELLGL--------
>tr|A8E5H0|A8E5H0_DANRE Sirtuin (Silent mating type information regulation 2 homolog) 6 (S. cerevisiae) OS=Danio rerio GN=sirt6 PE=2 SV=1
------------------------------ETLAQWIRESQYMVVHSGAGISTSTGIPDFRGPNGVWTMEERGE---------TPH----FNT----T--
FEDARPSLTHMALLQMQRT-GHLKYLISQNVDGLHVRSGFDRLSELHGNMFVEECEKCGKQYVRDTVVGTGRYCDSCR--GKLISSILDWEDSLPDLNRA
DEASRRADLALTLGTSLQIKPSGDLPLLTKRTGGKLVIVNLQPTKHDKHAHLRIYGYVDDVMGQLMKLLGL--------
>tr|M4AY07|M4AY07_XIPMA Uncharacterized protein OS=Xiphophorus maculatus GN=SIRT6 PE=4 SV=1
------------------------------ETLAQLIKESEYLVVHSGAGISTSSGIPDFRGPKGVWTLEEKGE---------SPH----FNT----T--
FEDARPSLTHLALLGLQRA-GYLKYLISQNVDGLHVRSGFDKLSELHGNMFVEECEKCGRQYVREKVIGTGRYCEACR--GKLISTILDWEDALPDLNRA
DDASRRADLALTLGTSMQIKPSGDLPLLTKRKGGKVVIVNLQPTKHDKHAHLRINGYVDDVMKQLMELLDL--------
>tr|C5L539|C5L539_PERM5 NAD-dependent deacetylase sirtuin-2, putative OS=Perkinsus marinus (strain ATCC 50983 / TXsc) GN=Pmar_PMAR014862 PE=4 SV=1
--------------------------------------CGKRIIVMAGAGISVSAGIPDFRTPGGLYYNGRPEDMFSMDFFKKNPYPFYHFAKHLWP---
TGQHRPTPTHYFVRLLQEK-GLLHRMYTQNIDGLERLAGVENLVEAHGTFSTASCIKCRAVVDPIDAIGNPVMCDVCSSVGLIKPDIVFFGESLPRFHLM
QSDFETCDLLIVMGTSLKVAPFNRLVSDVPD-TTVRLLVNREKQPGAGYRDIWMESDCDSGVEKIVDMM----------
>tr|A0A0L0FMS4|A0A0L0FMS4_9EUKA Uncharacterized protein OS=Sphaeroforma arctica JP610 GN=SARC_09745 PE=4 SV=1
----------------------------------IKSGKCKRIVVLQGAGVSTSAGIPDFRGPKGLYSQYYPEAIFDIGFFEKNPVP---FFSLAKSLF-
PGNFKPTYTHFFVRMLQEK-SLLKRCFTQNIDALERRAGIDLTVEAHGSFASGTCMDCGKGYPQDYVNDQLPCCAKCE--GVVKPDIVFFGENLPRFERA
NEDFDECDLLLIMGTSLKVAPFSHLCTFVDK-TCVRLMLNLEVPKVPSNRDVRYLGTCDEGCRQLTAML----------
>tr|H9J6E4|H9J6E4_BOMMO Uncharacterized protein OS=Bombyx mori GN=Sirt2 PE=4 SV=1
-------------------------------------DRCKKIITLSGAGISTSAGIPDFRSPTGLYHNLQPQAIFEINFFRQNPKP---FFTLAKELF-
PGSFKPTISHYFIRLLHEK-GLLLRHYTQNIDTLERGAGIEKLVEAHGTFYTSHCLDCRKEYPLEFFADQIPICTECP--GVVKPDIVFFGESLPRFQML
EEDFKQCDMLIIMGSSLEVQPFASLIDMVPD-SCPRLLINREKAGVRSYRDVARLGDCDEGCQDLADRL----------
>tr|A0A0K0EIP1|A0A0K0EIP1_STRER Uncharacterized protein OS=Strongyloides stercoralis PE=4 SV=1
---------------------------FTLEGIAKYIKENPKICFMVGAGISTSAGIPDFRTPTGLYDNYDPQDIFDLQFFDEDPRP---FYTLAKELF-
PTGVKPTTCHYFIKLVDEK-GLLKRCFTQNIDSLERIANIQKVVFAHGNHITSTCRVCKKKYNWLQANKLVPFCEECN--GVVKPDIVFFGENLPFFLGA
IHDIPACDLLIIMGTSLVVHPFASIVHEVRP-EVPRLLINMAAVGKKNIRDVFWPGACDDGVMELARLL----------
>tr|A0A0N4ZDP0|A0A0N4ZDP0_PARTI Uncharacterized protein OS=Parastrongyloides trichosuri PE=4 SV=1
---------------------------LTLEGIANYIKESPKICFMVGAGISTSAGIPDFRTPTGLYDNYDPQDIFDLSCFDEDPRP---FYTLAKELF-
PAGAKPTTCHYFIKLVDEK-GLLKRCFTQNIDSLETIANISKVVFAHGNHLTSSCRICKRKYDWLQEDNIVPLCEGCV--GVVKPDIVFFGENLPFFLGA
IHDIPTCDLLIIMGTSLVVHPFASIIHEVKP-HVPRLLINMTAVGKKNIRDVFWPGTCDDGAMELARLL----------
>tr|R7UFJ9|R7UFJ9_CAPTE Uncharacterized protein OS=Capitella teleta GN=CAPTEDRAFT_181192 PE=4 SV=1
-------------------------------RIAAMITKAKHLVAFTGAGISTSAGIGDFRGKSGKWTEEDRHGYDEPEAKRSRVDSDSNGVEG--EEVP
YEDLRPTFTHDAIFKLSEM-NHLKHIISQNADGLHLLSGITGLSELHGNVFIERCEKCGHRYERSFYKAHAKECTTCGCDGHLMDSIINFGDLLEILKKA
EDEAKKSDVMLILGSTVTVTPASALVTMGTK-PLKLIICNRQKTQFDDICGARVFGDCDVLMREVMKCILSQ-------
>tr|R7TRL9|R7TRL9_CAPTE Uncharacterized protein OS=Capitella teleta GN=CAPTEDRAFT_224786 PE=4 SV=1
-------------------------------RVTRMMKDSQYAIAFTGAGISTAAGIYDFRGKNGKWTERDREKYF-------------QYRRH--RDFC
YEELRPTYTHEAILKLLQL-GYIKHVISQNTDGLHRLSGIDKLSELHGNSFHEKCEKCQTRYERPFA--PPRICVHCHCDGPLMNTIINFGDSLEVLSIA
DEHAKRNDLVLCLGTTLRVTPACDLVEAGVR-PLRLVICNRQPTSFDRMCGARVYGDCDHFMREIMTSLLSA-------
>tr|K1PNH5|K1PNH5_CRAGI NAD-dependent deacetylase sirtuin-6 OS=Crassostrea gigas GN=CGI_10020906 PE=4 SV=1
-------------------------------HVAKLIKKSEYCIAFTGAGISTAAGIGDFRGITGKWTERDKAKKQ-------------GTK-V--PPRN
LQALRPTYTHEAIVKLLEK-GYMKHVISQNLDGLHRLSGVGQISELHGNGFVEKCEKCKKRYVRNFR--PVNKCTKCRCNGYLMNTIINFGDYLEVLDGA
EKHAEQSDLVLALGTTLQVSPANNLVESGQD-PTRLVICNRQVTDYDQTCGSRVFGDCDKMMRELMRSVLPG-------
>tr|K1PW50|K1PW50_CRAGI NAD-dependent deacetylase sirtuin-6 OS=Crassostrea gigas GN=CGI_10020907 PE=4 SV=1
-------------------------------RIAELLKQSNHCIAFTGAGISTAAGIGDFRGINGKWTTQEKVKQY-------------GVSKT--RGHN
MLDLRPTYTHEALLKLTDL-GYIKYVISQNTDGLHRLSGISKISELHGNAFMEKCEKCGNRYEWCRQ--PANTCERCGCGGFLMNTIINFGDYLEVLGSA
KHHAKRADLVLALGTTLQVSPANSLVEMGQK-PTRLVICNRQSTPYDNVCGSRVFGDCDKLMSEIMRNVLPK-------
>tr|I1G0C7|I1G0C7_AMPQE Uncharacterized protein OS=Amphimedon queenslandica GN=LOC100632618 PE=4 SV=1
-------------------------------MIVHLIMFSKHCVTFTGAGISTSAGIGDYRGKRGKWTKEDRKEEE---------------EEE--EGVP
YEQLRPTYTHESLVKLMEL-GHLKYVITQNGDGLHSLSGIDKLAELHGNVFEEFCESCDTKYARPYYINYGSQCPQCSCPGQLKDSIINFGDDLRVLTAA
TREARKCDLLLSLGSSMTVTPASDLISMGKK-PLSVVIINRQKTSFDDLCGVRVFGDTDDVMRLIMKELLKD-------
>tr|K1Q4C1|K1Q4C1_CRAGI NAD-dependent deacetylase sirtuin-6 OS=Crassostrea gigas GN=CGI_10023489 PE=4 SV=1
-------------------------------RVAGWLLSAKHCVVFTGAGISTAAGIGDYRGKSGKWTEMDHEQVSKIEQIFASGDEDQEDRGD--EGVD
YEELRPTFTHEALCRLVDL-DLVKHVVSQNGDGLHGLSGIEHLSELHGNVFIEKCEKCHHRYERTFYIEHAKRCDTCGCKGFLKDTIINFGDNLEILNRA
FEHAQQCDLMICLGSTLTVTPANELVEVIQK-TGRLVICNRQKTDYDDDCGCRVYGDCDTFIREILKNVIGD-------
>tr|C5LN96|C5LN96_PERM5 Neurofilament triplet L protein, putative OS=Perkinsus marinus (strain ATCC 50983 / TXsc) GN=Pmar_PMAR015517 PE=4 SV=1
--------------------------------------YWKRVVVLAGAGISVSAGIPDFRSPTGIYANRAPEDLFSIHYFRHDPYPFYRLCHE--AQLG
RGAHEPTAAHRFIAWLAEK-GALLRCYTQNIDSLEIDAGVELVVQAHGHLRSARCIDCGCPYGGDRDLEKPVHCAACY--GLVKPDVVFFGENLPFFDCV
QEDLSQATLLVVMGTSLQVGPCNQIPILLP-RTTPRLLVNLTPPPHDNYRDVFVEKDTDSASEELRKKL----------
>tr|A0A0L0V0F6|A0A0L0V0F6_9BASI Uncharacterized protein OS=Puccinia striiformis f. sp. tritici PST-78 GN=PSTG_13823 PE=4 SV=1
---------LKFLKARKKLPE--YNSI---DDAVSLIQRAEKILILTGAGISTSCGIPDFRSENGLYSQDDPHDMFDLPFFKSNPAPFYKFLKTIFPTST
TKSIIPSDSHRFIKMVESH-SKLLRNYTQNIDTLEMRAGVKNLIQCHGSFAKFTCLKCRAKYPASEFIGRVVLCPICSSLGLMKPDIIFFGEGLTEFDEA
IERRFECDLVIVIGTSLKVAPVSEIIKYVP-DGVPQILINRDPIYHGREFDICLFGQSDLILRELSRRLGPGWQ-----
>tr|A0A0J0XMD2|A0A0J0XMD2_9TREE SIR2-domain-containing protein OS=Trichosporon oleaginosus GN=CC85DRAFT_285808 PE=4 SV=1
----------------RRTKLAAHNSV---ADALALLRSARRIMVLSGAGISTSCGIPDFRSATGLYATDDPQQMFDIAYFREHPEVFYSFAKQ---IY-
PSNFVPSPCHRWIKMLEDR-GVLLRNYTQNIDTLESQAGVSRVLQCHGSFATASCLRCRARVPGHEYIQRIPFCPTCAAPGIIKPDITFFGQALDAFDEL
FRDREEVDLLVIIGTSLKVAPVSEVLSHIP-HSVPQIFINLTPVTH-VRPDILLLGDADSIVSYLSHEL----------
>tr|A0A0A3K591|A0A0A3K591_BURPE Sir2 family protein OS=Burkholderia pseudomallei ABCPW 111 GN=X946_2868 PE=4 SV=1
------------------------------DAAVRALSGADALLVAAGAGIGIDSGLPDFRGAEGLWRAYAFHEIASPRAFRERPRLAWGFYGHRLAMYR
--AVVPHEGFGILRRWAGAMRNGAFVFTSNVDGHFQKAGFVRIVEIHGSIHAMQCLRCSA-HTWSAPVGDVPTCAHCG--GIARPNILMFDDAEWLHDAL
RDWLARAVVVVEVGAGTAV-PTVRFFSER--IGDDVIRINLREAHARRADVIGLPGGALETLRALDAA-----------
>tr|A0A0P0H5I6|A0A0P0H5I6_BURPE NAD-dependent protein deacetylase OS=Burkholderia pseudomallei GN=cobB_2 PE=4 SV=1
------------------------------DAAVRALSRADVLLVTAGAGIGIDSGLPDFRGAEGLWRAYAFHEIASPRAFHERPRLAWGFYGHRLAMYR
--ATVPHEGFGILRRWIGAMRHGGFVFTSNVDGQFQKAGFERIVEVHGSIHAMQCMSCSA-HTWDAPVGALPRCPRCG--GLARPNILMFDDADWLHEAL
RAWLARAVAVVEVGAGTAV-PTVRAFSER--TGDDVIRINVREAHARRADVIGLPGGALETLRALDAA-----------
>tr|F2UAD1|F2UAD1_SALR5 Sir2 family transcriptional regulator OS=Salpingoeca rosetta (strain ATCC 50818 / BSB-021) GN=PTSG_05413 PE=4 SV=1
------------------------------KLAAQLLGTSTAIVVAAGAGMSLDSGLPDYRSPAEWTAALRYEDMAKAAHFDDSPRVVWAWYKHRYDTYQ
--AAQPHAGYAVLKRWCDGARDGYRVFTSNVDGFFQRAGFSSVVECHGSMARLQCTSKHG--IWKSDAAEVPRCRGCQ--RHARPNILLFKDTAWERGRY
GAWLDADLAILEVGAGNLV-PTVRLEVER--VVASRIRINPGRDVQWPGQHVVIRGKAFDILTSIDAA-----------
>tr|A0A0K6SB72|A0A0K6SB72_9ALVE Uncharacterized protein OS=Chromera velia CCMP2878 GN=Cvel_12728.t2.CR2 PE=4 SV=1
------------------------------NQLAALCRNAKHIVVHTGAGVSTAAGIPDFRGPKGVWTAKQK-R--------KKPPA--------SK--S
FDEARPTVTHLALAALYHA-GLVKYIVTQNVDGLHLKSGISALSEVHGTVFAEHCDRCHTEYPSWTEIHTGRGCPRCG--GGLRDKITDWDSDLPDKDRA
EDEHEKADLLIVLGSSLRVQPANQFPKYTFEEPGDLVIVNLQETELDSLCTLRFFGRCDNVMELLMQNLGL--------
>tr|A0A0G4IK50|A0A0G4IK50_PLABS Uncharacterized protein OS=Plasmodiophora brassicae GN=PBRA_004223 PE=4 SV=1
------------------------------AELARLVRSSRHCIVHTGAGISTSAGVHDFRGPDGVWTRQQR-K--------LPPLH--------GV--A
FGDAVPTITHMAIVALVRA-GLVKHVVSQNVDGLHVRSGLQHLCEVHGTAFAEWCDKCQCEFRRADEVATGNACKRCG--GPLRDLLCDWDSNLPEVEYA
IEQHRMADLAICVGTSLRIRPAGLWPLRTIREPGRICVINLQKTHLDRRCAVRIFARCDHVFTMLMDELGV--------
>tr|L7ITZ2|L7ITZ2_MAGOP NAD-dependent deacetylase sirtuin-2 OS=Magnaporthe oryzae (strain P131) GN=OOW_P131scaffold01535g18 PE=4 SV=1
--------------------------------------SPPGIIILAGAGISTSAGIPDFRSPTGLYDNLSPTDVFDINFFRTNPQP---FYSLAPELY-
PGRYAPTISHAFVALLARK-GLLAMLFTQNIDGLEKAAGVDLVVEAHGSFDSQRCIDCAQEFPAADHTSSVPHCGKCG--GLVKPDIVFFGEQLDRFFRA
REALEARQVVIVMGTSLSVPPFCELPVRAA-DGVPRLLFNREVVGFGERQDVVELGDCDSGVRKLAEML----------
>tr|A0A0F7SMI8|A0A0F7SMI8_PHARH Sirtuin 5 and related class III sirtuins (SIR2 family) OS=Phaffia rhodozyma PE=4 SV=1
----------------KRERLREYSTW---TDAIELIRRSKRILVLTGAGISVSCGIPDFRSTTGLYAKYDPQQMFELSYFKETPAVFYSFAHQ---IY-
PSNFTPSPCHRWIKLLEDK-GKLLRNYTQNIDTLESQVGIKNVLQCHGSFATASCLRCRRQMPGSADIRTIPRCTPCIQPAVIKPDITFFGEPLDRFDRC
FADRESVDLLLVIGSSLQVAPVSEVLAHLP-HSVPQILINKTPLKYF-DPDINLLGDADGIVRLLSEKLE---------
>tr|A5E2E7|A5E2E7_LODEL Putative uncharacterized protein OS=Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-42
------------------------------NETIKHIFKSKKTTVITGAGISCNAGIPDFRSDDGLYNMYRGQDLFDINLFRDDVSLFCTFMEGLYLS--
TLSARPTETHKFLKHLKDR-GKLLRCYTQNIDSLEKEVGILDVVQLHGNLHKLSCTRCFASFEWNEKYQNTPECQNCHKIGVLRPDIVLYGENHPQISQG
TDLRSKPDCLIIMGTSLKVDGVKKLVKSVHKKGGKVIFINKTKLSWEKFIDYEVLCDCDEFVRILKR------------
>tr|A0A0L0P7Z4|A0A0L0P7Z4_9ASCO Uncharacterized protein OS=Candida auris GN=QG37_00287 PE=4 SV=1
------------------------------HEVAKIIYKARKITALTGAGISCNAGIPDFRSDDGLYNLYKGQDLFDISLFRNQETLFCTFMEGLYKH--
SLAAKATETHRFIKTLKEK-NKLLRCYTQNIDSLEKRIGILDVVQLHGNLHKLLCTQCFSHYEWTPEAQENPECENCYLIGILRPDIVLYGENHPQLTRG
IDLGIKCDCLLIMGTSLKVDGVKKLVRSIHDRDGKVIFINKLPLPWANLVDYEILTDCDDFVRLLKK------------
>tr|H8X830|H8X830_CANO9 Hst3 histone H3 K56 (H3K56) deacetylase OS=Candida orthopsilosis (strain 90-125) GN=CORT_0E05440 PE=4 SV=1
------------------------------NEAIRYISKSKKTTVITGAGISCNAGIPDFRSENGLYNMYRGQDLFDINLFRDETSLFCTFMERLYHY--
SLLAKPTESHKFLKHLKDK-GKLLRCYTQNIDSLEQNVGILDVVQLHGNLHKLSCTNCFAEFEWNSEFKVNPECSNCYNIGLLRPDIVLYGENHRQLSQG
NDLKSKPDLLIIMGTSLKVDGVKKLVKSIHERGGKVLFVNKTNLSWHQYVDYEILCDCDQFIRILKA------------
>tr|S3C2N2|S3C2N2_OPHP1 Sir2 family protein OS=Ophiostoma piceae (strain UAMH 11346) GN=F503_02850 PE=4 SV=1
------------------------------DDAVHLLQTRKNIIVLTGAGISTSLGIPDFRSKTGLYSRSDPQEVFDINVFKDDPTI---FYSVARDILP
-STDRFTPTHAFIAMLQQR-GKLLTNYSQNIDNLEAKAGISKLIQCHGSFATASCVVCGYRVDGETTIGRIPRCPQCSAGGVMKPDITFFGESLPEFSRL
THDRDKVDLVVVIGTSLKVAPVSEVVPFMPA-HIPQIYISRTPVTH-INFDIDLLGDCDVVVSELCRRAG---------
>tr|A0A0C2FEJ7|A0A0C2FEJ7_9PEZI NAD-dependent histone deacetylase SIR2 OS=Sporothrix brasiliensis 5110 GN=SPBR_06821 PE=4 SV=1
------------------------------QDAVHLLQKSRNIIVLTGAGISTSLGIPDFRSKIGLYSRNDPQEVFDIHVFKEDPRI---FYSVARDILP
-STDRYTPTHAFIAMLQQR-GKLLTNYSQNIDNLEAKAGISKLIQCHGSFATATCVTCRYRVEGESTIGQIPRCPRCAAGGVMKPDITFFGEALPEFSRL
THDRDKADLVVVIGTSLKVAPVSEVVPYMPP-NVPAIYISRTPVNH-INFDIDLLGDCDVVVSELCRVAG---------
>tr|A0A0J9XAX3|A0A0J9XAX3_GEOCN Similar to Saccharomyces cerevisiae YPL015C HST2 Cytoplasmic member of the silencing information regulator 2 (Sir2) family of NAD(+)-dependent protein deacetylases OS=Geotrichum candidum GN=BN980_GECA06s02771g PE=4 SV=1
------------------------------DKLATDIGRFRNIVFMVGAGISTSAGIPDFRSPTGLYANLYPEAIFELDYFRKHPDP---FYQLALEINP
EKYNEPTIFHKFIADLAQR-GWVKRVYTQNIDTLERLAGVELIVEAHGSFAGNHCLDCRRPMSQARELKGRVNCDACKK-GLVKPDIVFFGEGLPRFECI
EEDFGAPDLVIVAGTSLTVHPFAGLPEMVGQ-KTVRVLINRDEVGSFRANDLVLLTSCDKFV-----------------
>tr|W7XB68|W7XB68_TETTS SIR2 family transcriptional regulator OS=Tetrahymena thermophila (strain SB210) GN=TTHERM_000672189 PE=4 SV=1
--------------------------------------QINNILFLTGAGISTSSGIPDFRSPNGLYSKEYPEQIFEIKYFTKNQMP---FYEMDKEFF-
--SNKPTSAHYFMAEVNRR-EQLLFVFSQNVDGLELEAGLEKLCQVHGNYRGARCQKCGFKHDINKFVQVIYKCENCKR-GPVRPNVVFFGESLDGFTKN
TYKIAAADCVFIMGTSMQVAPFNLTVEKIS-KNVPVIVINRDMVYLPYKKYIHLKNDIDDNIEKLMTDL----------
>tr|M8BII2|M8BII2_AEGTA NAD-dependent deacetylase sirtuin-6 OS=Aegilops tauschii GN=F775_11566 PE=4 SV=1
------------------------------EELAVMVQKSKHLVVFTGAGISTSSGIPDFRGPKGVWTLQRAGK--------GVPDASLPF---------
-HRAAPTLTHMALVELERA-GLLKFVISQNVDSLHLRSGFEKLAELHGNSFKEVCPCCKTEYLRDFEIETPRRCADCG--ARLKDTVLDWEDAPPEMNSA
EEQCRTADLVLCLGTSLQITPACNMPLLSIKNGGKVAIVNLQATPKDKKASLVIHGLVDKVIAGVMCI-----------
>tr|K1VLQ3|K1VLQ3_TRIAC Histone deacetylase OS=Trichosporon asahii var. asahii (strain CBS 8904) GN=A1Q2_05434 PE=4 SV=1
----------------RILRQRSKLTQYSVEDALELLKSSKNIMILSGAGISTSCGIPDFRSATGLYATYDPQQMFDISYFREHPEVFYSFAKQ---IY-
PSNFTPSPCHLWIKSVEDR-GCLLRNYTQNIDTLEQLAGVKNVLNCHGSFSTASCLRCKRRQPGDAHRQEIPWCEPCRAPGIIKPDITFFGQALEAFESL
YEDREKVDLLVIIGTSLKVAPVSEVLSHIP-HSVPQIFINLTPVTH-VNPDISLLGDADSIVTYLSDRLG---------
>tr|L8GM51|L8GM51_ACACA Transcriptional regulator, Sir2, putative OS=Acanthamoeba castellanii str. Neff GN=ACA1_076810 PE=4 SV=1
---------------------------------AELVRGARHLVVYTGAGVSTAANIPDFRGPQGVWTLMDQ-------GLEA-------------EGIP
LEAAVPTYTHMALVALQER-GVLRHLVSQNVDGLHLRSGIDNLSELHGNCYVEICDSCGAEYFRDFDVCTGRRCEDCYH-GQLRDNIINFGEQLPVLVNA
QDHSRKADVVIAIGTSLRVEPAASLPLKSVKRGGKLAIINLQKTPYDSSAHLRIFAHCDHVMQLLMQTLGV--------
>tr|F4PS83|F4PS83_DICFS 6-phosphogluconate dehydrogenase, decarboxylating OS=Dictyostelium fasciculatum (strain SH3) GN=gnd PE=3 SV=1
-----------------------------------KSGKAKNIIVLTGAGISVAAGIPDFRSPTGLYQNLYKTAIFDMEYFVENPKP---FFILAKELY-
PGSFNPTPVHHFIKLLSDK-GLLLRNYTQNIDTLERVAKIDYLVEAHGTFASAKCIKCKKVHSCEKDADEIPTCQDCS--AVVKPDIVFFGESLPRFSMV
QADFPKCDLMIVIGTSLQVQPFASLVAMAPA-NTPRLLINNEEVGISNKLDCKWIGDCQDGINELTTLLD---------
>tr|A0A0F7SG63|A0A0F7SG63_PHARH Sirtuin 2 (Silent mating type information regulation homolog) 2 ( cerevisiae) OS=Phaffia rhodozyma PE=4 SV=1
------------------------------KGFARLIAKAKNVVVMTGAGCSTNAGIPDFRSPDGLFHNYEPESIFELNFFRSNPAP---FYELAKELY-
PGKFLPTLTHFFIRLLQKH-GHLRRVFTQNIDTLERISGISFIVEAHGSFATSSCIDCHKPVDSMTHSSRIPYCKSCG--GLIKPDITFYGESLDRFFDC
IRDMSECDLLIVMGTSLKVHPFASLVDRVHP-TTPRMLINNEIVCGDEGRDVLVKGDCDSGCRSLAKEL----------
>tr|A0A0A3HME5|A0A0A3HME5_9BACI Uncharacterized protein OS=Lysinibacillus manganicus DSM 26584 GN=CD29_19640 PE=4 SV=1
------------------------------KKIAQFIATSEKIVVLTGSGISSGSGIQDYKKVESLWKK-DPFTMADLKVFANEPESFWNFYIFMKHLLH
IKAISTNDDHLFFVWLEKQLNKEVTIVTQNVDGLHQKAGSKKVVEYHGNIFECICPSCNSSYKLVNTANGLPRC-RCG--AILRPNVVFFGDEVHYQKQS
IEEVKQADLIIVMGTTLKTFPFNELVYHKN-EDANLILINEFHVEIEVDFDVVALGDITDICHKLWEEINQ--------
>tr|L7IP91|L7IP91_MAGOY Transport protein SEC7 OS=Magnaporthe oryzae (strain Y34) GN=OOU_Y34scaffold00021g4 PE=4 SV=1
-----------------------------------KSGKVKRITVMTGAGISTAAGIPDFRSPTGLYSNPEPEAVFDISFFRDRPEP---FYVLAKELY-
PGKFQPTISHAFIALLSKK-GLLQMNFTQNIDCLERQAGVEKVIEAHGSFATQSCIECKELFPDDEMKEIVPRCASCN--GLVKPNIVFFGEPLPTFSEK
CHLVAESDLAIIIGTSLTVYPFAGLPELVP-RGSPRLLLNKVRVGQTRSDDVVELGSCDAGVRKLADLL----------
>tr|A0A0N1GY19|A0A0N1GY19_9EURO NAD-dependent protein deacetylase hst4 OS=Phialophora attae GN=AB675_11651 PE=4 SV=1
---------------------------------LKAIKKRRKIVVVAGAGISVAAGIPDFRSADGLFQSLSGKELFDASVYKDDSAT-SSFHDMVRRLAL
SRDARPTLFHRLLARLSAE-GRLLRVYTQNVDGLENRLPWPKTIPVHGGLEKMVCQKCQYLADLDEELFRPPPCPECQTIGKLRPRMVLYHESPDE--EA
IGFKTRPDCVIVVGTSMKIKAMNRIAEEMCGKEGTTIWINHDPPPAKNLWDLVVRADADDIAQ----------------
>tr|W2SC13|W2SC13_9EURO Uncharacterized protein OS=Cyphellophora europaea CBS 101466 GN=HMPREF1541_00334 PE=4 SV=1
---------------------------------LKALRKRRKIVVIAGAGISVSAGIPDFRSSHGLFRSLSGKELFDASVYKDDSST-SSFHEMVRKLSQ
SQDAKPTLFHRLLARLSTE-GRLLRLYTQNVDGLESKLPWPKTIQLHGGLEKMMCQKCRQISNFEEELFQPPQCPECLTVGRLRPRIVLYNEHPDD--EA
IGFRTRPDAVIVVGTSMKIPAVRRITAEMCDKEGTTIWINRDPAPKDDCWDLIVRGDADEVAQ----------------
>tr|A0A0D2BJZ1|A0A0D2BJZ1_9EURO Uncharacterized protein OS=Exophiala xenobiotica GN=PV05_08402 PE=4 SV=1
---------------------------------LKALRNRKKIVVIAGAGISVSAGIPDFRSSHGLFNSLSGKMLFDASVYKDDHST-SSFHDMVRKLSK
SENAKPTAFHRFLARLSVE-GRLLRLYTQNVDGLESSLPWPQTIQLHGGLEKMMCQKCRHISDFEAHLFDPPLCPQCVAVGKLRPRIVLYNEHPDD--EA
IGFRTRPDAVVVVGTSMKIPAVRRIVHEMCDREGTTIWINRDPVPKDNLWDLVVKGDSDEVAR----------------
>tr|U1GC74|U1GC74_ENDPU Uncharacterized protein OS=Endocarpon pusillum (strain Z07020 / HMAS-L-300199) GN=EPUS_06207 PE=4 SV=1
---------------------------------LKTLRKRRKIVVVAGAGISVAAGIPDFRSSHGLFENLSGKGLFDASVYKDDSST-STFHDMVRDLSS
ASKAKPTLFHQLVARLSCE-GRLLRLYTQNIDGIDTSLPWPQTIQLHGGLEMMMCQKCQHTSGFQPELFQPPLCPKCMEIGKLRPRIVLYNEHPDE--DA
IGLRTRPDAIIVVGTSMKIPGVKRIVREMCSRDGVSIWINRDPVPKEDCWDLVVKGDSDEVAR----------------
>tr|V9D616|V9D616_9EURO Uncharacterized protein OS=Cladophialophora carrionii CBS 160.54 GN=G647_06413 PE=4 SV=1
---------------------------------LKAVRNRRKIVVVAGAGISVSAGIPDFRSSHGLFKSLSGKMLFDASVYKDDHST-AEFHKMVRKLSK
ADNAKPTLFHRFLARLAVE-GRLLRLYTQNVDGLESSLPWPKTIQLHGGLEKMMCQKCRHISDFQAHLFDPPLCPQCVAVGKLRPRIVLYNEHPDD--EA
IGFRTRPDCVIVVGTSMKIPAVRRIVREMCDREGTTVWINHEPVPKDDCWDLIVSGDSDEVAR----------------
>tr|G1WZZ1|G1WZZ1_ARTOA Uncharacterized protein OS=Arthrobotrys oligospora (strain ATCC 24927 / CBS 115.81 / DSM 1491) GN=AOL_s00006g192 PE=4 SV=1
---------------------------------NDILNKKKKIIVIAGAGISVCAGIPDFRSSNGLFASVSGKQLFDASVYRDDQST-SDFHDMVRNLHA
ANVAEATAFHHLLASLAAS-GKLLRLYTQNVDCIETGLAWPKTIQLHGGLDKMNCTKCRAIKDFKPEIFVPPDCPDCVDIGKLRPRMVLYNEHPDE--DA
IGLKARPDCLIVVGTSLKIPGVQRLVRELCDRGGKTVWINRDDPPGQGLFDLIIKGDCETLAK----------------
>tr|D2VCI1|D2VCI1_NAEGR Silent information regulator family protein OS=Naegleria gruberi GN=NAEGRDRAFT_66580 PE=4 SV=1
------------------------------EHLVNLINQSKHIVLYTGAGISRAAGIRDYRSPNGVWTMKEK-GVKTV-A-KKDE-----------S---
-KIIFPTRTHMAISTLYNA-GKIQYVTSQNVDGLHVKSGIKNMSELHGNTNVEICHKCNIEYVRNFDHRTGRFCEKCK--SELEDTIINFNENLPQLERA
EENASKADLAIVVGTSMRVNPACSLPQMCKENGGKLVIINLQLTPKDKKADLRIFAEADKVIDTVMKKLAL--------
>tr|D2VZT9|D2VZT9_NAEGR Silent information regulator family protein OS=Naegleria gruberi GN=NAEGRDRAFT_81867 PE=4 SV=1
------------------------------DELAQLLQSSKHVVFYTGAGISTSAGISDFRGPNGIWTMKEK-GMKAK-A---SS-----------S---
-TIKLPTPTHMAIATLYQR-GMIKYVTSQNVDGLHVKSGFKDISELHGNTNVELCKNCNCEYLRTFDHKTGRMCEHCG--HELEDSIINFGENLPQLDRA
ELNAKKADLAIVLGTSLRVSPACDLPEMCLKKGGKMVIVNLQKTPKDKKSSLRIFAKTDDVINGIMERLSL--------
>tr|G8BCH4|G8BCH4_CANPC Putative uncharacterized protein OS=Candida parapsilosis (strain CDC 317 / ATCC MYA-4646) GN=CPAR2_803900 PE=4 SV=1
----------------KRDRLDDVSTY---EDAINLIRDSKRILVITGAGISTSLGIPDFRSSKGFYSMSDPQEVFDLEIFQTDPTL---FYSIAHMIL-
PPGHTFTPLHSFIQVLQSK-NKLLRNYTQNIDNIESYAGIENLVQCHGSFATATCLTCGDNIPGESEIQELPRCKACDRFGIYKPDITFFGEALPRFDHI
GEDIINCDLLISIGTSLKVAPVADIVDKIP-HYVPQILINKDPIEH-CNFDVSLLGYCDEVISFIANKLGDDWKL----
>tr|H8WWF7|H8WWF7_CANO9 Uncharacterized protein OS=Candida orthopsilosis (strain 90-125) GN=CORT_0A03930 PE=4 SV=1
----------------KRDRLDDVSTY---QDAIDLIRESKRIIVITGAGISTSLGIPDFRSSKGFYSMSDPQEVFDLEIFHTDPTL---FYSIAHMIL-
PPEHTFSPLHSFIQLLQSK-NKLLRNYTQNIDNIESYAGVENLIQCHGSFAGATCTSCGHNVPGESDIQELPRCKKCEPFGVFKPDITFFGEALPRFDHI
REDIMNCDLLISIGTSLKVAPVADIVDKIP-HYVPQILINKDPIDH-CNFDVSLLGYCDEVISFIADKLGDDWKL----
>tr|S7ZTY4|S7ZTY4_PENO1 Uncharacterized protein OS=Penicillium oxalicum (strain 114-2 / CGMCC 5302) GN=PDE_07191 PE=4 SV=1
------------------------------KLLVDTLRHQKDIIAIAGAGISTAAGIPDFRSPDGLFKSYSGKLLFDAAVYQ-DETLTGPFHELVRSLWE
AANCQPTKFHEMLASLGKE-NRLKRLYTQNIDGLETSMKWPITIQLHGSITKMVCQKCRHLSNLDPEKFEAPDCDECAGVGRMRPRVVLYNEHPDEITSV
MDIKSRPRALVVAGTSLKIPGVRRLVKSLRGKDGVTMYIGKEPLVFEDCFDLIVQGSTDEVAD----------------
>tr|A0A0F7TQ93|A0A0F7TQ93_9EURO Uncharacterized protein OS=Penicillium brasilianum GN=PMG11_07573 PE=4 SV=1
------------------------------KLLVDTLRHQKDIVAIAGAGISTSAGIPDFRSTDGLFKSHSGKLLFDAAVYQ-DDALTGPFHELVRSLSV
AAKCQPTKFHEMLASLGQE-NRLKRLYTQNIDGLETSMKWPITIQLHGSITKMVCQKCRHLENLEPNKFDPPDCEECAGVGRMRPRIVLYNEHPDEITSV
MDIKSRPRVLIVAGTSLKIPGVRRLVKSLRSKDGVTMFINNEPPAFENCFDLIVQGSTDDVAD----------------
>tr|A0A0A2K8U1|A0A0A2K8U1_PENEN Sirtuin family OS=Penicillium expansum GN=PEX1_024020 PE=4 SV=1
------------------------------HLLVQTLRHQKDIVVIAGAGISTAAGIPDFRSTDGLFKSHSGKLLFDAAVYQ-DDALTAPFHEMVRSLSE
VANIKPTAFHKMLARLGIE-SRLKRLYTQNIDGIETSMGWPVTIQLHGSIEKMVCQKCRYLDNFKPDMFDPPACEECTVIGRMRPRIVLYNEHPDEITSV
MDIKSRPRVLIVAGTSLKIPGVRRLVKSLRSKDGVTMFINNEPPSFDNCFDLIIKGSCDEVAR----------------
>tr|A0A0J6YN04|A0A0J6YN04_COCIT Sir2 family protein histone deacetylase Hst4 OS=Coccidioides immitis RMSCC 2394 GN=CIRG_08215 PE=4 SV=1
------------------------------ELLVSALQNKRKIVVVAGAGISVSAG-PDFRSSHGLFKTHSGKELFDASVYL-DSTMTSSFHDMVRLLSD
AATAKPSAFHHLLARLAKE-DRLLRLYTQNIDGIDTSLPWPRTIQLHGGLKKMICQKCRHTSDFKAHLFDPPLCPECCEVGKLRPRIVLYNEHPDEIGSV
VDLRTRPDALVVVGTSLKIPGVRRIVKEMQGKDGITMWINHDSPVFEHCWDLVVQGDCDEVAE----------------
>tr|C1G4Q0|C1G4Q0_PARBD Uncharacterized protein OS=Paracoccidioides brasiliensis (strain Pb18) GN=PADG_01916 PE=4 SV=1
------------------------------GLLLKALQKKRKIVVIAGAGISVSAG-PDFRSSHGLFKTHSGKQLFDASVYR-DNSMTSSFHDMVRSLSR
AASAKPTAFHHLLARLAKD-GRLMRLYTQNVDGIETSLPWPRTIQLHGGLEKMVCQKCRHTSDFEAELFDPPLCRKCCEVGKLRPRIVLYNEHPDEIGSV
VDLRARPDALIVVGTTLKIPGVRRIVKEMRGKDGITMWINHEPPVFESCWDLVIKGDCDEVAR----------------
>tr|A0A017S2X5|A0A017S2X5_9EURO DHS-like NAD/FAD-binding domain-containing protein OS=Aspergillus ruber CBS 135680 GN=EURHEDRAFT_416619 PE=4 SV=1
------------------------------DLLVKTLQKHRKIVVIAGAGISTSAGIPDFRSTDGLFKSHSGKLLFDASVYQ-DDTLTASFQDMVRSLSE
AEKTSPTAFHHMLASLGQE-NRLTRLYTQNIDGIETSMPWPRTIQLHGSLDKMVCQKCRHLGTFDRDMFDAPECPECSRVGKMRPRIVLYNEHPDEITSV
MDIRSRPDALIVVGTSMKIPGVRRLVKSLKGKNGVTMWINNEPPTFEDSFDLMVKGDCEEVAR----------------
>sp|Q5BE04|HST4_EMENI NAD-dependent protein deacetylase hst4 OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) GN=A
------------------------------NLLVNTIRNHKKIVVIAGAGISTSAGIPDFRSDDGLFKTHSGKLMFDAAVYQ-DEALTASFQEMVRSLSE
AEKSSPTAFHHMLARLGSD-NRLTRLYTQNIDGIETSMPWPRTIQLHGSLEKMVCQKCRHMSTFDRVMFDAPECPECVLIGKMRPRIVLYNEHPDEITSV
MDIRSRPDALIVVGTSLKIPGVRRLVKSLRSRNGVTMWINNEPPSFEDCFDLLVKGDCEEVAR----------------
>tr|A0A093V6K5|A0A093V6K5_TALMA NAD-dependent protein deacetylase hst4 OS=Talaromyces marneffei PM1 GN=GQ26_0142090 PE=4 SV=1
------------------------------NLLTKTLRNQRKIIVIAGAGISTSAGIPDFRSSDGLFKSHSGKLLFDAAVYR-DDSLTASFHEMVRTLSK
AADTKPTAFHHMLARMAKD-NRLSRLYTQNIDCIETSLQWPTCIQLHGSLDKMVCQKCRHLAEFDPNLFEAPACPACTEVGKMRPRIVLYNEHPDEIAAV
MDIRSRPDTVIVVGTSLKIPGVRRLVKSLRSPKGIAMWINNEPPVFEDCWDLVVKGNCEEVAR----------------
>tr|V5GDP9|V5GDP9_BYSSN SIR2 family histone deacetylase (Hst4), putative OS=Byssochlamys spectabilis (strain No. 5 / NBRC 109023) GN=PVAR5_8950 PE=4 SV
------------------------------ELLKKTLRKHRKIVVIAGAGISTSAGIPDFRSTDGLFKSHSGKLLFDAAVYR-DDSLTASFHEMVRSLSE
AAKSTPTAFHHLLARLAKE-NRLSRLYTQNIDCIETSMPWPRTIQLHGSLDKMVCQKCRHLSEFQRELFDAPLCPACSEVGKMRPRIVLYNEHPDEIASV
MDIRSRPDALIVVGTSLKIPGVRRLVKDMRGRNGVTMWINNDLPVFEDCWDLMVTGDCEEVAR----------------
>tr|A0A0F4YH67|A0A0F4YH67_TALEM SIR2 family histone deacetylase (Hst4) OS=Rasamsonia emersonii CBS 393.64 GN=T310_8523 PE=4 SV=1
------------------------------DLLVKTLRTRRKIVVIAGAGISTSAGIPDFRSSNGLFKSHSGKLLFDAAVYR-DESLTASFHEMVRTLSE
AARSSPTAFHHMLARMAQD-NRLVRLYTQNIDCIETSMPWPRTIQLHGSLDKMVCQKCRHLADFRRELFDAPLCPACSEVGKMRPRIVLYNEHPDEIASV
MDIRSRPDALVVVGTSLKIPGVRRLVKNLRSRNGITMWINNEPPVFENCWDLMVQGDCEEVAR----------------
>tr|A0A0F8WP82|A0A0F8WP82_9EURO Putative SIR2 family histone deacetylase (Hst4) OS=Aspergillus ochraceoroseus GN=AOCH_004632 PE=4 SV=1
------------------------------DLLVKTIRRHRKIVVIAGAGISTSAGVPDFRSTDGLFKSHSGKLLFDAAVYQ-DENLTASFQDMVRSLSE
AANTSPTAFHHMLARLGHE-NRLTRLYTQNIDGIETSMPWPRTIQLHGSLDKMVCQKCRYLRDFDRAMFDAPECPECSIIGKMRPRIVLYNEHPDEITSV
MDIRSRPDALIVVGTSLKIPGVRRLVKSLRGRNGITMWINNEPPSFEDCWDLMVRGDCEEVAR----------------
>tr|A0A094DNN9|A0A094DNN9_9PEZI Uncharacterized protein OS=Pseudogymnoascus pannorum VKM F-4515 (FW-2607) GN=V496_05160 PE=4 SV=1
------------------------------QRLLKVLRTKRKIVVIAGAGISVSAGIPDFRSSTGLFTSHSGKHLFDAAVYK-NDDDTASFHEMVREMSH
TRQANPTMFHHMIATIAEE-GRLMRLYTQNVDGIDTSLEWPKTIQLHGGLEKMVCTKCRALSDFDGSLFEPPSCKACEEIGRLRPRIVLYNEYPDEIGAV
TDLKSRPDAVIVVGTSLKVPGVKRIAREMRGKDGFTAWINNMPPVFKDCWDLVIRGDCDEVAR----------------
>tr|A0A0C9R7Q0|A0A0C9R7Q0_9HYME Sirt7_0 protein OS=Fopius arisanus GN=Sirt7_0 PE=4 SV=1
-------------------------------RLAGAISRASSLAVYTGAGISTAASIPDYRGTNGVWTRMQGKEIGN-------------------HDLS
--LAEPTVTHMALYALYKA-RVLKHIVSQNCDGLHLRSGIPFLSEVHGNMYVEVCRGCKPEYLRLFDVGTGRHCHECN--SLLQDSIVHFGERPWNWNGA
CRASKQADVILCLGSSLKVLKKYPWLWQAH-KRCSLYIVNLQWTPKDENATLKINGRCDEVMKRVMSHLGL--------
>tr|K7IWQ7|K7IWQ7_NASVI Uncharacterized protein OS=Nasonia vitripennis GN=LOC100120550 PE=4 SV=1
-------------------------------RLAAAISRATSLAVYTGAGISTAASIPDYRGTNGVWTRLQGKDIGN-------------------HDLS
--QAEPTITHMALYALYKA-RMLKHIVSQNCDGLHLRSGIPLLSEVHGNMYVEVCRTCKPEYWRLFDVSTGRTCHKCN--SPLQDSIVHFGERLWNWNGA
SRAAKQADVILCLGSSLKVLKKYPWLWQVA-KRPQLYIVNLQWTPKDDNAVLKINGKCDQVMKIVMSHLGI--------
>tr|T1HCW3|T1HCW3_RHOPR Uncharacterized protein OS=Rhodnius prolixus PE=4 SV=1
-------------------------------KLASAIKHSQHLVIYSGAGVSTAASIPDYRGSNGIWTRLQGKDIGN-------------------HDLS
--AAEPTVAHMALYALYRK-GLLKYVVSQNCDGLHLRSGLPALSEVHGNMNLEVCTDCNVQVWRSFDVKTARRCSQCF--HPLRDTIVHFGERAWNWSGA
CQAAKQADVILCIGSSLKVLKKYPWLWGAK-KRPQLYIVNLQWTPKDDQASLKINGKCDDVMKLVMRYLNL--------
>tr|F4WBC8|F4WBC8_ACREC NAD-dependent deacetylase sirtuin-7 OS=Acromyrmex echinatior GN=G5I_02836 PE=4 SV=1
-------------------------------RLAAAISRATSLAVYTGAGISTAASIPDYRGTNGVWTRMQGKDIGN-------------------HDLS
--QAEPTLTHMALYALYKA-RILKHVVSQNCDGLHLRSGIPFLSEVHGNMYVEVCRTCKPEYWRLFDVGTGRLCHRCN--SVLQDSIVHFGERPWNWNGA
TRAAKQADVILCLGSSLKVLKKYPWLWQVQ-KRASLYIVNLQWTPKDENAILKINGKCDEIMRKIMSHLGL--------
>tr|D7EHQ9|D7EHQ9_TRICA Putative uncharacterized protein OS=Tribolium castaneum GN=TcasGA2_TC002298 PE=4 SV=1
-------------------------------ILAQAIAQAQHLVVYTGAGISTAAKIPDYRGPNGIWTRLQGKDIGA-------------------HDLS
--MAEPTYTHMALSELYRN-KILKYVVSQNCDGLHLRSGLPALSELHGNMYIEVCKTCKPEYWRLFDVKTSRRCYVCN--EPLVDTIVHFGERQWNWAGA
CKNAEKATTIVCLGSSLKVLKKYPWLWRAK-KRPNLYIVNLQWTPKDDVANVKIHGKCDQVMEAVMNLLDI--------
>tr|C4JSC8|C4JSC8_UNCRE Putative uncharacterized protein OS=Uncinocarpus reesii (strain UAMH 1704) GN=UREG_05367 PE=4 SV=1
---------------SKRLKLPQYNTI---DDAVELLKRSKNIVVLTGAGISTSLGIPDFRSKDGLYSKNDPQDVFDISLFLEDPSI---FFSVAKDILP
-TEKRFSPTHAFIKLLQDK-GKLLTNFTQNIDNLEANAGVSKLIQCHGSFATATCTKCHIQVSGDAIVGLVPQCQACTDPGVMKPDITFFGEDLPAFDRL
INDRDIADLVIVIGTSLKVAPVSGVPGIMP-QNVPHLFISRTPVSH-IDFDIDMLGDCDVVVSELCQRAGWDLKHEMI-
>tr|A0A0C2H4W8|A0A0C2H4W8_9BILA Transcriptional regulator, Sir2 family OS=Ancylostoma duodenale GN=ANCDUO_00822 PE=4 SV=1
------------------------------SELAQMLLRSKCVFVVTGAGISTSAGIADFRGPKGVWTIEKEGRVAESV--------------------D
FSRARPTLTHRALRLLEER-GLVKFVVSQNVDGLHPKSSFNRLAELHGNVFCEQCERCSRRYYREFATEGTPKGRACR--GRLRDTTLDWEDALPDLTTA
YSFFQNADLSLCLGTSLQIVPVSDMPLLAKKNGGKMVTVNLQATKHEKKTDLAIHGFVDDVMVRVLKHLDIPL------
>tr|U6NKF2|U6NKF2_HAECO Uncharacterized protein OS=Haemonchus contortus GN=HCOI_00273300 PE=4 SV=1
------------------------------AQLADLLRQSRCTFVVTGAGISTSAGIADFRGPNGVWTIEKEGRVAESV--------------------D
FTRARPTLTHHALRILEER-GLIKFLVSQNVDGLHPRSSFNRLAELHGNVFCEQCERCSRRYYRNFPTEGTPKGRACR--GRLRDTTLDWEDALPDFTIA
YNY--HADLSLCLGTSLQIVPVGDMPLLAKKNGGKMVTVNLQATKHEKKTDLAIHGLVDDVMMRVLSHLGIKL------
>tr|A0A0K0D3C9|A0A0K0D3C9_ANGCA Uncharacterized protein OS=Angiostrongylus cantonensis PE=4 SV=1
------------------------------EALARLLLQSKCVFVVAGAGISTSAGIPDFRGPNGVWTTEKDGRVPESV--------------------D
FTHARPTFTHHALRVLEER-GLIKCVLSQNVDGLLPRSSFNRLAELHGNVFCERCEKCSRHYYRDFAIEGNPNGRTCR--GRLRDTTLDWEDALPHFTIA
NNY--NADLSLCLGTSLQIVPVGDMPLLAKRNGGKVVTVNLQATKHEKKVDLAIHGLVDDVMNRVLRFLGISL------
>tr|A0A0R3TTF2|A0A0R3TTF2_HYMNN Uncharacterized protein OS=Hymenolepis nana PE=4 SV=1
----------------------------------ISTGKAKNIITAVGAGISTSAGIPDFRSPTGLYSNLDPMDVFDLNFFEDNPEP---FFKVAKSLY-
HPNAKPTLAHYFIKLLNDK-GLLLRDYTQNIDMLERTAGIEKLIEAHGSYNTGRCLKCKKKYPFEYFEQKVPTCSKCD--EVIKPDIVFFGEDLPRYKGV
QKDFRKCDLLIIMGTSLKVAPFNHVIDYPN-SKVPRLLINRELSENDNLRDVFFQGDSDDGCLRLAELL----------
>tr|V6LV53|V6LV53_9EUKA NAD-dependent histone deacetylase Sir2 OS=Spironucleus salmonicida GN=SS50377_11414 PE=4 SV=1
-----------------RLRLPQISSF---DTVLRLFQTCKNIVFLVGAGISVSSGIPDFRSKNGIYANLRPTDMFDLSFFKENPLPFFKFVPEIM---P
QSKYKPTLTHKFISQIFQT-NKLCRIYTQNIDCLELKSGVQKILSAHGSFASSSCMVCKKKVGLEEDIYEIPLCQVCCPACILKPDIVFFGEKVDTLDFI
AKDSLKIDLLIVMGSSLKVKPIAGLIGAIPR-HVPQILINRERISGAHEFDVEMIGNCDDCLLRVAKGLK---------
>tr|A0A0L0D8W2|A0A0L0D8W2_THETB Sir2 family histone deacetylase Hst2 OS=Thecamonas trahens ATCC 50062 GN=AMSG_00557 PE=4 SV=1
------------------------------DAFVGKILELRNVIVLAGAGLSVAAGVPDFRSDAGLYAAYFPEAVFELDFFRSNPRPFYALASAMFSET-
-DTVSPTLAHWFLRLLHDR-GLLLRVYTQNIDGLEADTGLEVVIPVHGSFVDAHCIDCGASYEIDVVSADIPRCADCA--GLIKPAIVFFGESLPFFEHS
REDVAIADAIIVMGTSLTVQPVASLPSRVSP-TIPRLLINRERTPADNYRDVLALGNLDDQVVRLCHALGPDW------
>tr|A0A085NHS5|A0A085NHS5_9BILA DNA helicase OS=Trichuris suis GN=M514_18824 PE=3 SV=1
---------------RRRRRLEQYNTI---NDVVNLIKQSKKVMVLTGAGVSVSCGIPDFRSKGGLYEMSDPQTIFDIKYFRYNPRPFFVFAKVNRQEIY
PDLFSPSLTHRFIKYLELE-GKLLRNYTQNIDSLENAAGIERVVYCHGSFTTASCITCKFKVDIEPDILRIPICPHCGTKSIMKPDVVFFGEDLPAFTNL
TKDQSEVDLLLVIGSSLKVGPVNAIPGMLR-DDVPQVLINREPLPN-YTFDVELLGNCDEIFNELALRLGEPF------
>tr|R9AGA9|R9AGA9_WALI9 NAD-dependent histone deacetylase SIR2 OS=Wallemia ichthyophaga (strain EXF-994 / CBS 113033) GN=J056_004549 PE=4 SV=1
-----------------RSRISIPETY---DAAINLISISSNILVVSGAGISVNRGIPDFRSPDGIYDQDEPEQIFDLATFVAHPRL---FYSVAKNIMP
-THFSPGPAHKFVKALQDS-DTLLRNYTQNIGPLERKAGVDLLLECHGTFAFLECLRCGEMYNTDDFSGGVPVCTKCIKIPYLKPTITFFGEDVSDYQRV
LDDSQATDLILVLGTSMSVAPISEFISHIP-HKVPIVVINKTPIK----------------------------------
>tr|I4YJB9|I4YJB9_WALMC DHS-like NAD/FAD-binding domain-containing protein OS=Wallemia mellicola (strain ATCC MYA-4683 / CBS 633.66) GN=WALSEDRAFT_3461
------------------ENVITSKDL---NDAIKLIEKSSKIVVVSGAGISVNCGIPDFRSKGGLYDSSDPQEIFSYYVFTNHPKL---FYSIVKSILP
-SNFSPGRAHSFIKALQDN-DKLLRNYTQNIDTLERKAGITNLLECHGSFAFLECLRCERIYNSDDFSGEIPVCTECKRIPFLKPTITFFGEDVPDYQNV
LEDSQIVDLVLVLGTSMAVAPISELLAHIP-HKVPVIVINNTPIK----------------------------------
>tr|A0A0L0T985|A0A0L0T985_ALLMA Uncharacterized protein OS=Allomyces macrogynus ATCC 38327 GN=AMAG_15777 PE=4 SV=1
----------------------------------HALYHAKRVVVVAGAGISVSAGIPDFRSENGLYALSKGQDLFDAALFRAEARLFYQFMAGLRDATR
--AANPTLTHRFLRSLDER-GSLLRVYTQNIDGLESRAGITRVVELHGSLDTVRCTRCADQFPFTSRFGAAPACPSCLRTGALRPNVVLYNETHPAGDEI
ADLRKRPDVLVVMGTSLKVHGIKRLVRDFHKKHGLVILVNRTPLPWGDVFDVVLTGDADDVVHQWVLEWQ---------
>tr|A0A0L0S418|A0A0L0S418_ALLMA Uncharacterized protein OS=Allomyces macrogynus ATCC 38327 GN=AMAG_18009 PE=4 SV=1
----------------------------------PVLHRAKRIVVVAGAGISVSAGIPDFRSPDGMYALHRGQDWFDAGVFRTEARLFYSLMGSMRAAAL
--AASPTPTHEWLAALESR-GSLLRCYSQNIDDLEPRAGLDSLVQVHGTLSRVRCVVCHRTAPHSDEVGNAPPCVACETIGVVRPDVVLYNETHPAGDEI
ADANRRPDVLIVMGTSLAVPGIKHLVRDMRTRNGHVILVNRTTLAWEGVFDTVITADADTVVEGWNHEFA---------
>tr|T1INU6|T1INU6_STRMM Uncharacterized protein OS=Strigamia maritima PE=4 SV=1
--------------------------INTLDDVIDLLRTKQKIIVLTGAGVSVSCGIPDFRSRDGIYARPDPQAMFDIHYFRKDPRPFYKFAK---EIY-
PGQFDPSLSHKFIKLLEKH-EKLLRNYSQNIDTLEQIADIERVIQCHGSFATATCTKCCFKVDSKDDIQNIPKCPKCKDLAVMKPDIVFFGEGLDEFHTM
AQDKDECDLLIVIGSSLKVRPVALIPHSVS-VDVPQILINREPLKH-MSFDVELLGDCDVIINEICLRLGPGWDQ----
>tr|A0A0M0UEZ8|A0A0M0UEZ8_9PEZI NAD-dependent protein deacetylase hst4 OS=Madurella mycetomatis GN=MMYC01_G02236 PE=4 SV=1
----------------------------SLGRLLSALRKKKKIVVIAGAGISVSAGIPDFRSSTGLFATHSGKHLFDASVYKHDSS-TESFHTMVRELAQ
MSKAKPTPFHHMLASIAAE-GRLMRMYSQNIDTLDTQMPWPTTIQLHGGLEKMVCTKCGHLEPFNASLFEPPLCEKCKEIGRLRPRIVLYNEYPDEINVK
ADLRRVPDAVIVVGTSLKIPGVRRIVKEMCQRDGITAWINLDPEPQEDCWDLVIRGKCDDIA-----------------
>tr|G4U8G1|G4U8G1_NEUT9 DHS-like NAD/FAD-binding domain-containing protein OS=Neurospora tetrasperma (strain FGSC 2509 / P0656) GN=NEUTE2DRAFT_100675 P
----------------------------NLDRLLTALRRKKKIVVIAGAGISVSAGIPDFRSSTGLFATHSGKHLFDASVYKHDDS-TESFHTMVRELAQ
LSQAKPTPFHHMLASMAEE-GRLLRLYTQNIDTLDTQMPWPVTVQLHGGLEKMVCTKCSHLEPFNAELFEAPLCAKCKEIGRLRPRIVLYNEYPDEINVK
ADLKRVPDAVIVVGTTLKIPGVRRLVKEMCQRDGITAWINIDPEPQEDCWDYVIRGKCDDVA-----------------
>tr|R8BC48|R8BC48_TOGMI Putative dhs-like nad fad-binding domain-containing protein OS=Togninia minima (strain UCR-PA7) GN=UCRPA7_7604 PE=4 SV=1
----------------------------QLDRLLSVLRKKKKIVVIAGAGISVSAGIPDFRSSHGLFQTHGGKSLFDASVYRDDKS-TEEFHKMVRDLSR
LQSAKPTPFHHMLASLAEE-GRLMRLYSQNVDCIDTSMKWPATIQLHGGLEKMVCTKCGQIDDFEASLFQPPPCKKCEAIGRLRPRMVLYQEYPDSIAVN
SDLRRVPDAVIVVGTSLKVPGVQRIVKLLCRRDGFTAWINLESEPQGDLWDLVVKGKCDDIA-----------------
>tr|A0A0G2FQ07|A0A0G2FQ07_9PEZI Putative dhs-like nad fad-binding domain-containing protein OS=Diaporthe ampelina GN=UCDDA912_g03916 PE=4 SV=1
----------------------------NLERLLNILRRKKKIVVIAGAGISVSAGIPDFRSREGLFKTHGGKSLFDASVYKDDKS-TEEFHKMVRDLSS
LKEAKSTPFHHMLATIAQE-GRLMRLYSQNVDCLDTSLKWPVTIQLHGGLEKMQCTKCSHVNSFDGSLFQPPLCEECREIGRLRPRMVLYNEYPDEIKVQ
ADLRRVPDAVIVVGTSLKVPGVRRIVRELCLRDGFTAWINLDPVPQDDLWDLVVRGKSDDIA-----------------
>tr|G0SEV8|G0SEV8_CHATD NAD-dependent histone deacetylase-like protein OS=Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719) GN=CTHT_0
----------------------------GLNRLLTALRKKKKIVVFAGAGISVSAGIPDFRSSTGLFAS-NGKHLFDASVYKHPHL-IADFHSMVRKLAE
LSKAEPTPFHHMLASLAAE-GRLMRMYSQNIDTLDTKMPWPTTIQLHGGLEKMVCILCGNIEPLRPELFDLPLCEKCEEIGKLRPRIVLYNEPPDEINVK
ADLRRVPDAVIVVGTTLKVPGARRLVKEMCKRDGLTVWINIDPEPQDDCWDLVVRGRADDVA-----------------
>tr|B2AYT2|B2AYT2_PODAN Podospora anserina S mat+ genomic DNA chromosome 1, supercontig 2 OS=Podospora anserina (strain S / ATCC MYA-4624 / DSM 980 / F
----------------------------NLQRLLTALRKKKKIVVIAGAGISVSAGIPDFRSSTGLFTTHSGKHLFDASVYKHDSS-TTSFHDMVRELSQ
MSEAKPTPFHHMLASIASE-GRLMRLYTQNIDSLDTQMPWPTTIQLHGGLEKMVCTKCNHLETFNPSLFQPPLCEKCKEIGKLRPRIVLYNEYPDEIMVK
ADLRRVPDAVVVVGTTLKIPGVRRLVKELCQRDGLTAWINLDPEPQEDCWDLVIKAKCDDVA-----------------
>tr|A0A0D9NYX5|A0A0D9NYX5_METAN Uncharacterized protein OS=Metarhizium anisopliae BRIP 53293 GN=H634G_05831 PE=4 SV=1
----------------------------HMERLLSALRKKKKIVVVAGAGISVSAGIPDFRSSTGLFAAHSGKHLFDASVYKHESS-TSSFHTMVREMSE
MKNAHPTPFHHLLASLAQE-GRLLRLYSQNIDCIDTSMKWPTTIQLHGSLDKMVCTKCADIQPFQGDIFDAPLCESCKNIGRLRPRFVLYNEFPDEINVR
ADLRARPDAVLVVGTTLKVPGTRRLVKQLCQKDGLTAWLNIDPEPKDDCWDLVVKSTCDNIA-----------------
>tr|S3E243|S3E243_GLAL2 DHS-like NAD/FAD-binding protein OS=Glarea lozoyensis (strain ATCC 20868 / MF5171) GN=GLAREA_07677 PE=4 SV=1
----------------------------KLKKLTEVLRSKRKIVVIAGAGMSVSAGIPDFRSSTGLFTTHSGKELFDASVYKDDRA-TSSFHDMVRELSH
RKQAKPTPFHHMLATLAEE-GRLLRLYSQNVDGIDTSLEWPKTIQLHGGLEKMVCTKCKTCLDFDAALFEPPDCPVCTEIGRLRPRMVLYNEFPDGIMVE
ADLKTKPDAVIVVGTTLKIPGTRRLAREMCQRGGFTAWINLDQPPSDDCWDMVVTAECDDIA-----------------
>tr|A0A0B1P1U4|A0A0B1P1U4_UNCNE Putative sir2 family histone deacetylase OS=Uncinula necator GN=EV44_g1541 PE=4 SV=1
----------------------------KLKKLLEIFRTKRKIVVFAGAGISVSAGIPDFRSSTGLFKTFSGKQLFDADVYRSNDA-TSSFHAMVRELSR
KKNVKPTPFHDMLATLAEE-GRLLRLYTQNVDGIDVRIQWPKAIQLHGGLGKMVCSKCSHLADFDASLFEAPPCSQCEEVGRLRPRILLYNEHPDEIAVF
ADINKGPDAVIVVGTSLQVPGIRRLAREMCLKNGFTAWINHDPEPSDDCWDMVVRADCDDIA-----------------
>tr|A0A0F7ZQ59|A0A0F7ZQ59_9HYPO Uncharacterized protein OS=Hirsutella minnesotensis 3608 GN=HIM_04016 PE=4 SV=1
----------------------------HLQRLLSALKKKKKVVVIAGAGISVSAGIPDFRSSTGLFATHSGKHLFDASVYKHDSS-THSFHTMVREMAH
LKNASPTPFHHLLASLANE-GRLLRLYSQNIDCLDTSMPWPPTIQLHGGLQNMVCTKCTEVKPFNADLFDAPLCESCKVIGRLRPRFVLYNEFPDEINVR
ADLKARPDAVIVVGTTLKVPGTRRLVKEMCQRDGLTAWINIDPEPKEDCWDLVVRSKCDDVA-----------------
>tr|A0A0A1TKX4|A0A0A1TKX4_9HYPO Uncharacterized protein OS=Torrubiella hemipterigena GN=VHEMI06338 PE=4 SV=1
----------------------------QMDRLTAELRKKKKIVVIAGAGMSVSAGIPDFRSSNGMFAQHSGKHLFDASVYKHDSS-TQSFHNMVREMVA
MKNAKATPFHQLLASLAKE-GRLLRLYSQNIDCIDTNLPWPATVQLHGGLENMVCTKCGELSPFDESRFDAPLCKTCKEIGRLRPRFVLYNEFPDEINVS
ADLRARPDAVLVVGTTLKVPGTRRLVKELCQRDGFTAWINPSPEPKDDCWDLVVKAKCDDVA-----------------
>tr|T4ZWX8|T4ZWX8_OPHSC Sir2 family histone deacetylase Hst4 OS=Ophiocordyceps sinensis (strain Co18 / CGMCC 3.14243) GN=OCS_06678 PE=4 SV=1
----------------------------HLQRLLSALRGKRKIVVIAGAGISVSAGIPDFRSSTGLFATHSGKHLFDASVYKHDSS-TQSFHAMVRDMAH
LKGAVPTPFHHLLASLAKE-GRLLRLGSQNI--VDTSMEWPPTIQLHGGLQKMVCTKCGDLKPFNGDLFSAPLCEMCEEIGRLRPRFVLYNEFPDEINVR
ADLKSRPDAVIVVGTTLKVPGTRRLVKEMCQKDGFTAWINIDPEPKEDCWDLVVRSKCDNVA-----------------
>tr|G0R744|G0R744_HYPJQ Deacetylase OS=Hypocrea jecorina (strain QM6a) GN=TRIREDRAFT_54330 PE=4 SV=1
----------------------------QEKRLVAALRKKKKIVVIAGAGISVSAGIPDFRSSSGLFARHSGKHLFDASVYRHDSS-TQHFHAMVREMDE
LKKATPTHFHRLLASLAQE-GRLMRLYSQNIDGLDANMKWPATIQLHGGLQKMVCSKCGHLAPFNSELFDAPLCEACTVIGRLRPRFVLYNEYPDEINVS
ADLKARPDCVIVVGTTLKVPGTRRLVKEMCQRDGLTIWINTDAEPKLDCWDLVVRSPCDKVA-----------------
>tr|K3UYD8|K3UYD8_FUSPC Uncharacterized protein OS=Fusarium pseudograminearum (strain CS3096) GN=FPSE_02025 PE=4 SV=1
----------------------------LLNRLRDTLRKKKKIVVIAGAGISVAAGIPDFRSSTGLFASHSGKHLFDASVYKHDDT-TESFHAMVREMAA
KKSAKPTPFHHLLASLAHE-GRLLRLYSQNIDCIDTSMEWPTTIQLHGGLQKMVCTKCSSLQEFDGEIFTPPLCPTCKDIGRLRPRFVLYNEYPDEINVS
ADLKTRPDAVVVVGTTLKVPGTRRLVREMCQKNGVAIWINLDDEPKDNCWDIVVRSKCDNVA-----------------
>tr|C7YHD8|C7YHD8_NECH7 Putative uncharacterized protein OS=Nectria haematococca (strain 77-13-4 / ATCC MYA-4622 / FGSC 9596 / MPVI) GN=NECHADRAFT_1031
----------------------------QMERLLTALRKKKKIVVIAGAGISVSAGIPDFRSATGLFATHSGKHLFDASVYKHDAT-TRSFHNMVREMAQ
MQSAKPTPFHHLLASLAQE-GRLLRLYSQNIDCIDTSMKWPATIQLHGSLEKMVCTKCGQLQPFDGSVFDAPLCGACVVIGRLRPRFVLYNEFPDEINVR
ADLKARPDAVLVVGTTLKIPGTRRLVKELCQRDGITAWINLDSEPKDNCWDIVVRSKCDNVA-----------------
>tr|M7T1D4|M7T1D4_EUTLA Putative nad-dependent histone deacetylase sir2 protein OS=Eutypa lata (strain UCR-EL1) GN=UCREL1_9444 PE=4 SV=1
----------------------------LLDQLTSALRKRKKIVVIAGAGISVSAGIPDFRSSHGLFATHSGKHLFDASVYKHDST-TASFHNMVRELAH
LRNAEPTPFHHLIASLAKE-GRLLRLYSQNVDGLDTSMTWPKTIQLHGGLAKMVCSKCGEISDFDGSLFETPPCKACEEIGRLRPRMVLYNEFPDEINVK
ADLRARPDAVLVVGTSMKIPGVRNMVKDMCQKDGLAAWINLDAEPSDDCWDLVVQGKCDHVA-----------------
>tr|W9Q5C0|W9Q5C0_FUSOX Uncharacterized protein OS=Fusarium oxysporum f. sp. pisi HDV247 GN=FOVG_00884 PE=4 SV=1
----------------------------QLKRLIDTLRKKKKIVVIAGAGISVSAGIPDFRSSTGLFATHSGKHLFDASVYKHDST-TQSFHAMVREMAT
MKAAKPTPFHELLASLAQE-GRLLRLYSQNIDCLDTQLKWPVTIQLHGGLQKMVCTKCNNIREFNGEVFDAPLCPTCKDIGRLRPRFVLYNEYPDEINVS
ADLKARPDAVLVVGTTLKVPGTRRLVREMCQKNGTAIWINVDDEPKDNCWDIVVRSKCDDVA-----------------
>tr|A0A0P7BC77|A0A0P7BC77_9HYPO NAD-dependent protein deacetylase hst4 OS=Neonectria ditissima GN=AK830_g8494 PE=4 SV=1
----------------------------RMERLVAALRKKKKIVVIAGAGISVSAGIPDFRSSTGMFATHSGKHLFDASVYRHDES-TQSFHAMVREMAQ
MQTAKPTPFHHLLASLAQE-GRLLRLYSQNIDCIDTSMKWPATIQLHGGLEKMVCTKCNQLEPFNGEVFDAPLCRTCEVIGRLRPRFVLYNEYPDEINVS
ADLKTRPDAVLVVGTTLKVPGTRRLVKEMCQKNGLTVWINLDSEPKDDCWDIVVRSKCDNVA-----------------
>tr|A0A0L0NM94|A0A0L0NM94_9HYPO NAD-dependent protein deacetylase hst4 OS=Tolypocladium ophioglossoides CBS 100239 GN=TOPH_00170 PE=4 SV=1
----------------------------HLQRLLSALRKKKKIVVIAGAGISVSAGIPDFRSPTGLFATHSGKHLFDASVYKHNSS-TQSFHTMVREMAQ
MKTASPTPFHHLLASLAKE-GRLLRLYSQNIDCIETSMEWPLTIQLHGGLQKMVCTKCGDLQPFNGELFNAPLCEACEEIGRLRPRIVLYNEYPDEINVR
ADLKARPDAVLVVGTTLKVPGTRRLVKELCQKDGFTAWINIDAEPKEDCWNLVVRSKCDNVA-----------------
>tr|J4WHY4|J4WHY4_BEAB2 Sir2 family protein OS=Beauveria bassiana (strain ARSEF 2860) GN=BBA_01435 PE=4 SV=1
----------------------------QMDRLLSVLHKKKKIVVVAGAGISVSAGIPDFRSSNGLFATYSGKHLFDASVYKHDSS-TQSFHKMVRDMSA
MAKAVPTPFHHMLASLAQE-GRLLRLYSQNIDCLDTQMEWPKTIQLHGGLQHMVCTKCSELSPLKAELFNPPLCAACTEIGRLRPRFVLYNEYPDEINVS
ADLRTRPDAVIVVGTTLKVPGTRRLVKELCQKDGFTAWINLSPEPKDDCWDMVVQSECDNVA-----------------
>tr|A0A0L9SGM5|A0A0L9SGM5_9HYPO Uncharacterized protein OS=Ophiocordyceps unilateralis GN=XA68_253 PE=4 SV=1
----------------------------HLQRLLSALRTKKKIVVIAGAGISVSAGIPDFRSSTGLFATHSGKHLFDASVYKHDAS-TQSFHTMVRQMAH
LSKAAPTPFHHLVASLAKE-GRLLRLYSQNIDCIDTSMEWPPTIQLHGGLQKMVCTKCGDLQPFNGDLFDPPPCAECEQIGRLRPRFVLYNEYPDEIKVR
ADLKARPDAVVVVGTTLKVPGTRRLVKEMCQKDGFTAWINVDPQPKDDCWDLVVRSRCDDVA-----------------
>tr|W9CDW1|W9CDW1_9HELO Uncharacterized protein OS=Sclerotinia borealis F-4157 GN=SBOR_5611 PE=4 SV=1
----------------------------QMKRLVSVLRGKRKIVVVAGAGISVSAGIPDFRSSTGLFSSHSGKELFDASVYKDDSS-TTSFHSMVRELSH
LKNAKPTPFHHMLATLAEE-GRLLRLYSQNVDGIDIALEWPKTIQLHGGLAKMVCSKCGHLQDFDGALFEAPDCDNCVEIGRMRPRMVLYNEYPDEIAVA
ADLKKVADAVIVVGTSLKIPGIRRLVKEMCSKNGFTAWINLDGEPGEDCWDLIVRGECDEVA-----------------
>tr|F0XKY6|F0XKY6_GROCL Sir2 family histone deacetylase OS=Grosmannia clavigera (strain kw1407 / UAMH 11150) GN=CMQ_8130 PE=4 SV=1
----------------------------ELSHLIQALQKKKKIVVIAGAGISVSAGIPDFRSSTGLFTTHSGKHLFDASVYKHDAS-TSSFHAMVRELAH
LQKARPTSFHHMLASIATE-GRLMRLYSQNIDGIDTALKWPVTIQLHGGLEKMVCSKCGNLESFDGSRFDPPECDECAEIGRLRPRIVLYNEYPDEINVR
ADLRRGPDAVIVVGTSLKIPGVRRLVKELCQRDGMTAWINVDNEPQEECWDTIVRGSCDDIA-----------------
>tr|A0A086SU48|A0A086SU48_ACRCH NAD-dependent protein deacetylase-like protein OS=Acremonium chrysogenum ATCC 11550 GN=ACRE_086720 PE=4 SV=1
----------------------------HLKRLVTALRKKKKIVVVAGAGISVSAGIPDFRSSTGLFAPQSGKHLFDASVYKHDAS-TQSFHTMVREMAD
MKKAQPTPFHHLLASLAQE-GRLLRLYSQNIDCIDTSMDWPTTIQLHGGLENMVCTKCGKLDEFRGEIFDAPLCEWCKEIGRLRPRFVLYNEYPDEINVA
ADLKARPDAVLVVGTSLKVPGTRRLVKEMCQRDGFTAFINIDSEPKEDCWDLVVRAKCDKVA-----------------
>tr|A0A0B7JPJ1|A0A0B7JPJ1_BIOOC Uncharacterized protein OS=Bionectria ochroleuca GN=BN869_000002939_1 PE=4 SV=1
----------------------------LRQRLVTALKKKKKIVVIAGAGISVSANIPDFRSSTGLFAAQSGKHLFDASVYKHDAS-TQSFHTMVREMAE
MNKAKPTPFHQMLASLAQE-GRLLRLYTQNIDCIDTSMKWPKSIQMHGGLEKMVCTKCGDLSPFRGEVFDAPLCAACEEIGRLRPRFVLYNEYPDEINVR
ADLKTRPDAVLVVGTSLKVPGTRRLVKEMCQRDGFTAWINVDSEPKEDCWDVVVRSKCDVVA-----------------
>tr|A0A084B4T9|A0A084B4T9_STACH Uncharacterized protein OS=Stachybotrys chartarum IBT 7711 GN=S7711_05638 PE=4 SV=1
----------------------------QMDRLVSVLRKKKKIVVIAGAGISVSAGIPDFRSANGLFATHSGKHLFDASVYKHAAS-TQSFHTMVREMAE
MNKAKPTPFHHLLASLANE-GRLMRLYSQNIDCIDIKMEWPVTIQLHGGLEKMVCTKCSDLQDFQAELFEAPLCGACKDIGRLRPRFVLYNEYPDEIKVS
ADLKARPDAVIVVGTSLKVPGTRRLVKELCQKDGFTAFINVDSEPKYDCWDLVVRARCDDVA-----------------
>tr|A0A0M9VTR2|A0A0M9VTR2_9HYPO NAD-dependent protein deacetylase hst4 OS=Escovopsis weberi GN=ESCO_000995 PE=4 SV=1
----------------------------QMERLATLLRKKKKIVVIAGAGISVSAGIPDFRSSSGLFARHSGTQLFDASVYKHDSS-TESFHTMVREMAD
MRRAEPTPFHHLLASLSQE-GRLLRLYSQNIDCLDTNMKWPTTIQLHGGLQKMVCSKCHQLEPFQSELFDAPLCNACRVIGRLRPRFVLYNEFPDGINVA
ADLKTRPDAVIVVGTTLKVPGTRRLAKEMCQRDGLTVWINLEPEPKEDCWDIVVRAKCDDVA-----------------
>tr|J3P9G9|J3P9G9_GAGT3 Sir2 family histone deacetylase Hst4 OS=Gaeumannomyces graminis var. tritici (strain R3-111a-1) GN=GGTG_10150 PE=4 SV=1
----------------------------LLTRLMTALRKKKRIVVIAGAGISVSAGIPDFRSSNGLFTTHSGKQLFDVSVYKDDFS-TSAFHKMLKELAT
IERAQPTPFHHMLASMAQE-GRLMRLYTQNIDCLDTDMEWPKTIQLHGGLQHMVCTKCGRLQDFDHRRFDPPSCPICEAIGRLRPRIVLYNEYPDAIEVS
ADLRRIPDAVIVVGTTLKIPGVRRLVREMCKRDGFTAWINVDGEPQDDCWDLVVKARCDDVA-----------------
>tr|A0A0G2GT77|A0A0G2GT77_9EURO Putative sir2 family histone deacetylase hst4 OS=Phaeomoniella chlamydospora GN=UCRPC4_g04308 PE=4 SV=1
----------------------------SLDLMLKALRRRRKIVVVAGAGISVSAGIPDFRSSHGLFRTHSGKQLFDASVYKNDSS-TESFHNMVRSLSN
LAKAHPTPFHRLLARLAKE-DRLLRLYSQNVDGIECTLPWPKTIQLHGGLEKMVCHKCKQISKFDPEMFTPPLCQACEEIGRLRPRIVLYNETPDEIAVA
SDLRARPDAVIVVGTSLKIPPVRRIVKEMCLQNGITMMINKENMALDDCFDVLIEGESDEVA-----------------
>tr|G2XF42|G2XF42_VERDV NAD-dependent histone deacetylase SIR2 OS=Verticillium dahliae (strain VdLs.17 / ATCC MYA-4575 / FGSC 10137) GN=VDAG_08774 PE=4
----------------------------KLDRLVDTLRYQKKIVVIAGAGISVSAGIPDFRSKQGLFATHSGKHLFDASVYKHDET-TEKFHKMVCDLAT
MKSAKPTKFHHLLASLAAE-GRLMRLYTQNVDCVDTNMPWPKTIQLHGSVEHMNCSKCGQITPLNTELFVAPLCAECTEIGRLRPRMVLYNEYPDEINVS
SDLKGRPDAVIVVGTSLKIPGVRRLVKELCQRGGFTAWINLDSEPQDDCWDLVVRGKSDDVA-----------------
>tr|A0A0P4U6C2|A0A0P4U6C2_ROSNE Putative sir2 family protein OS=Rosellinia necatrix GN=SAMD00023353_0802120 PE=4 SV=1
----------------------------LLAQLTDALRKKKKIVVIAGAGISVSAGIPDFRSSSGLFATHSGKHLFDASVYKHDST-TSHFHTMVRDLSQ
LKDAKPTSFHHFLASLAKE-GRLLRLYTQNVDGLETSMEWPKTIQLHGGLEKMVCSKCNEISQFDASLFEAPLCKGCEEIGRLRPRMVLYNEYPDEINVR
ADLRTRPDAVIVVGTSMKIPGVRNMVKDICKRAGMTAWINLDSEPSDNCWDLVVRGKCDDVA-----------------
>tr|L2GJ71|L2GJ71_COLGN Nad-dependent histone deacetylase sir2 OS=Colletotrichum gloeosporioides (strain Nara gc5) GN=CGGC5_15093 PE=4 SV=1
----------------------------KLARLVSALKKRKKIVVIAGAGISVSAGIPDFRSKKGLFATHSGKHLFDASVYKHDSS-TEKFHKMICDLSN
MKAAEPTPFHHLLASLAHE-KRLLRLYSQNVDCIDTSMEWPTTIQLHGSVEHMVCSKCADIKPLKTELFVAPLCEECVMIGRLRPRMVLYNEFPDEIKVS
VDLKSRPDAVIVVGTSLKIPGVRRLVKELCQRDGFTAWINTDSEPQDDCWDLVVRGKCDDVA-----------------
>tr|G4MSV1|G4MSV1_MAGO7 Sir2 family histone deacetylase Hst4 OS=Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) GN=MGG_04588 PE=4 SV=1
----------------------------LLARLTKVLRKKKRIVIIAGAGISVSAGIPDFRSQSGLFKS-NGKHLFDVSVYHDDSL-TSAFHKMVRELAT
KQAASPTPFHHMMASIAQE-GRLLRLYTQNIDCLDTGMEWPKTIQLHGGLAKMQCTKCGDVKDLDPELFDPPLCAVCEEIGRLRPRMVLYNEAPESVTVA
ADLARVPDAVIVVGTTLKIPGVKRLVTEMCRRDGFTAFLSVEP-PQEECWDIVVRGKCDDVA-----------------
>tr|A0A060SZ10|A0A060SZ10_BLAAD ARAD1A16082p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1A16082g PE=4 SV=1
-----------------RKRLPYPRKV---EEFCEVLKKAKNVLVITGAGISTSLGIPDFRSETGLYSRSDPQEVFDIHLFREDPSI---FYSIAREILP
GSEKRPSPTHAFIKLLHDK-GKLLRNYTQNIDNIEANAGVEKLVQCHGSFATVTCQTCGYKDQGYADIAKVPKCPKCTPAHVLKPDITFFGEPLPRFDDP
EGDAAKCDLVICIGTSLKVAPVSEIIRIVS-RDTPQVYISKTAIRH-NEFDVTLLGPSDDVVEWLVDRINES-------
>tr|A0A0J9X9A4|A0A0J9X9A4_GEOCN Similar to Saccharomyces cerevisiae YDL042C SIR2 Conserved NAD+ dependent histone deacetylase of the Sirtuin family involved in regulation of lifespan OS=Geotrichum candidum GN=BN980_GECA05s06775g PE=4 SV=1
------------------------PQTFHMDTLVDTIRKAKNIIVLTGAGISTSLGIPDFRSKSGLYNKSDPQEVFDLGLFNSDPSV---FYSVAKEILP
-VTTKFSPTHAFLRLLQEK-GKLLRNYTQNIDNLEHFAGIEKLVQCHGSFATATCQTCMYQTPGEDDISRIARCPKCCPFGVMKPDITFFGEPLPKFEQT
GGDADRCDLLLCIGTSLKVSPVSETVRIIP-HSVPQFYISKTPISH-IDFDLTLLGACDDIVEHLCRELGWELDHPM--
>tr|A0A0G4HJ15|A0A0G4HJ15_9ALVE Uncharacterized protein OS=Chromera velia CCMP2878 GN=Cvel_7063 PE=4 SV=1
-------------------------------------GKVKNVVVMTGAGLSVAAGIPDFRSPGGLYSQPRPEDIFTLSYYKKKPEPFCKLAQE---IF-
PGKYHPTRAHFLAPLLAQK-GLLLRHYTQNIDNLDQTAGSENLIEAHGSFRDVHCTNCSKQHPWLRDMEDTKMV-PCN--GPVKPDIVFFGEPVPKFMNS
ETVAASADLLLILGTSLEVMPFASLLGKVSP-LCPRVLINKTPVAINNYRDVFLQGTTDDGVTQLCRELG---------
>tr|A0A0G4GAR5|A0A0G4GAR5_9ALVE Uncharacterized protein OS=Chromera velia CCMP2878 GN=Cvel_21032.t1.CR1 PE=4 SV=1
-------------------------------------GKAKNIVVMTGAGLSVAAGIPDFRSPGGLYSQPEPEDMFNLDFYTENPEAFCTFAKE---LF-
PGNFHPTRAHFLSPLLAKK-GLLLRHYTQNIDNLD--AGVEKLVEAHGSFRDAHCTGCRKRFPWVR--ETKEKV-PCN--SPVKPDIVFFGESLPRFN--
EDDMPKCDLLIVLGTSLEVMPFASLTSKVSH-MCPRLLINKTPVALNNYRDVFLQGTCDDGVTILCEELG---------
>tr|A0A086TIG0|A0A086TIG0_9FUNG NAD-dependent deacetylase sirtuin 2 OS=Mortierella verticillata NRRL 6337 GN=MVEG_12422 PE=4 SV=1
-----------------RIRILKDDTV---ESIAENQGKAKKIIVMTGAGISTAAGIKDFRSPTGLYDDYFPEAVFDLAFFKETPGP---FYRLAKELF-
PGKYRPTLTHYLLPLLAKK-GLLLRSYTQNIDSLEKMAGLDLLVEAHGSFSTAKCIQCAIVSEWVKEISNIPYCKRCG--GLVKPEITFFGEDLPRFDMA
QTDFVDCDLLIVLGTSLKVEPFNKLITQVST-RCPRLLINREKAGQESQRDAWFLGDCDVGVKKLVSL-----------
>tr|A0A0B6Z6J2|A0A0B6Z6J2_9EUPU Uncharacterized protein (Fragment) OS=Arion vulgaris GN=ORF50768 PE=4 SV=1
---------------------------------------------------------PDFRSRGGVYARPDPQAMFDINFFRSDPRPFFKFA---REIY-
PGQFKPSPCHRFIRMLEEK-GRLLRNYTQNIDTLEQVSGIQKVVQCHGSFATSKCTVCGHVVDSDADIQVIPRCPRCSPGAIMKPDIVFFGESLPHFNQM
AADKDDCDLLIVIGSSLKVRPVALIPNSLP-ASIPQILINRERLPY-LNFDVELLGNCDDIIGELCRRLGPGWEE----
>tr|A0A0F4YIK2|A0A0F4YIK2_TALEM RNA methylase family protein OS=Rasamsonia emersonii CBS 393.64 GN=T310_7999 PE=4 SV=1
----------------KRQKLPEYNTI---EDAVELLKKSKNIIVITGAGISTSLGIPDFRSKTGLYSRSDPQEVFDIRLFREDPSI---FFSIAKDILP
-TEKKFSPTHAFIRV-------------------------EKIVQCHGSFATATCTKCKYQVPGETTVRKVPECKRCKEPGVMKPDITFFGEDLDEFGRL
HHDRDIADLVIVIGTSLKVAPVADVPAIMP-SNVPQLYISRTPVSH-IGFDIDLLGDCDVVVSELCRRAGWELKHEMI-
>tr|A0A0D2M8X9|A0A0D2M8X9_9CHLO Mono-ADP-ribosyltransferase sirtuin 6 OS=Monoraphidium neglectum GN=MNEG_8254 PE=4 SV=1
-------------------------------RLAEMVRCAERVVAFTGAGISTACGIPDFRGPGGVWTLQRAGKP--------PPRLQTS----------
FVYAKPSLTHMALVALMQA-GKLTYICSQNVDGLHLRSGVPQLAELHGNCFAERCRRCGAEYVRDFEMDTGRGCTRCR--GKLHDHILDWEDALPELDET
ERRADEADLSICLGTSLQIVPAANLPLRTLKTGGQLAIINLQATPKDRRATLVVHARVDGVMALLLRRLG---------
>tr|E1Z747|E1Z747_CHLVA Putative uncharacterized protein OS=Chlorella variabilis GN=CHLNCDRAFT_20462 PE=4 SV=1
-------------------------------RMAELVRGARRIIAFTGAGISTACGIPDFRGPEGIWTLQRAGQP--------LPRPKVS----------
FTHAKPSLTHQVLAALMLT-GKLDYLVSQNVDGLHLRSGIPCLAELHGNCFAERCHACGTEYVRDFEVETGRKCSQCS--ASLRDQILDWEDALPELELS
EDHAKEADLAICLGTSLQITPACNLPLKATREPGQLVIVNLQRTQAVKSGGLVCHARCDEVMRLLARKLQ---------
>tr|S7RN74|S7RN74_GLOTA DHS-like NAD/FAD-binding domain-containing protein OS=Gloeophyllum trabeum (strain ATCC 11539 / FP-39264 / Madison 617) GN=GLOT
------------------------------GKLLKAILKAKRIAVVCGAGISVHAGIPDFRSPEGLFQTLSGRDLFDASVFNSESSLFCQMIAHLSELS-
-QTAVPTPFHNLLRTLDDR-GRLLRVYTQNIDALESKCGLRRCIPLHGTLQRVHCQTCHHSFPLEDHLSQPPACPECASVGKLRPSVVLYNEDHREGEVV
RKDLAGADLLLVVGTSLRVPGTKRIVREFAKRNMKSIYLNLDFTRWEGVFDVWVKGDAQSFAQMLDEEIG---------
>tr|A0A0L6X2Y3|A0A0L6X2Y3_9AGAR NAD-dependent histone deacetylase HST3 OS=Termitomyces sp. J132 GN=J132_10197 PE=4 SV=1
------------------------------SRIIKFILKAKRIVVICGAGISVQAGIPDFRSTDGLFKSLSGKDLFDASVFNSEHALFCQMIAQLWSLS-
-QAAKPTAFHNVLRALDDR-GKLLRVFTQNIDAIEEKCGLK-CVPLHGTLQSMHCQICNCSFPLEEYLPQPPQCPECTSVGKLRPSVVLYNEAHKDGEVV
KKDLSGADLLLVVGTSLRVPGTKRMVREFAKRGMKAIYLNLDFTRWEGVFDAWIQGDAQVFAEMLQAEIE---------
>tr|A8NUH2|A8NUH2_COPC7 Hst3 protein OS=Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003) GN=CC1G_07104 PE=4 SV=2
------------------------------PKVIQAIMKAKRIVVICGAGISVQAGIPDFRSQDGLFKTLSGKDLFDASVFNTEQSLFCQMMAQLADLS-
-QNAEPTSFHHFLRALNDH-GRLLRVYTQNIDAIEQKCGLKRCIPLHGTLQEMYCQACRRSFPLQDHLPQPPDCPECTNIGRLRPSVVLYNEAHHDGDVV
QKDLSGADLLLVVGTSLKVPGTKRMVREFAKRGIKAIYLNLDFTRWEGVFDAWVQGDAQTFAEMMREEIR---------
>tr|A0A0C9X4E8|A0A0C9X4E8_9AGAR Unplaced genomic scaffold K443scaffold_370, whole genome shotgun sequence OS=Laccaria amethystina LaAM-08-1 GN=K443DRAFT_113516
------------------------------AKVIQAILKAKRIVVICGAGISVQAGIPDFRSPDGLFKSLSGKDLFDASVFNSETSLFCQMVAQLSDLS-
-QAAQPTAFHHLLRELDQR-GRLLRVYTQNIDAIEQKSGLKRCIPLHGTLQSMHCQICSHSFPLHLYLPHPPQCPECAAIGKLRPSVVLYNEAHKNGEVV
KKDLSGADLLLVVGTSLRVPGTKRMVREFSKRGMKAVYLNLDFTRWEGVFDAWIQGDAQEFAEMVRGEIG---------
>tr|A0A0D0BEG2|A0A0D0BEG2_9HOMO Unplaced genomic scaffold CY34scaffold_129, whole genome shotgun sequence OS=Suillus luteus UH-Slu-Lm8-n1 GN=CY34DRAFT_805734 P
------------------------------RKAIKAILKAKRLVVVCGAGISVSAGIPDFRSESGLFQTLSGRDLFDASVFNNEHSMFCQMIAQLSELS-
-QAASPTPFHQALRSLDDR-GRLLRVYTQNIDAIELKSGLRRCIPLHGTLQTLHCQTCMHTFPLENYVSTPPYCPECTQVGKLRPSVVLYNELHKDGEVA
RRDLSGVDTLLVVGTSLKVPGTKRLVREFSKRGIKSIYLNFDFTRWDGVFDMWLQGDAQNFADLLQEEIA---------
>tr|A0A0C9TVJ0|A0A0C9TVJ0_PAXIN Unplaced genomic scaffold PAXINscaffold_22, whole genome shotgun sequence OS=Paxillus involutus ATCC 200175 GN=PAXINDRAFT_13531
------------------------------RKAARAILKAKRLVVVCGAGISVNAGIPDFRSPTGLFQTLSGKDLFDASVFNSEHSLFCQMIAQLSELS-
-QAASPTPFHQLLRSLDER-GGLLRVYTQNIDAIESKSGLKRCIPLHGTLQTLHCQTCTHTFPLEDYMDTPPYCPECTQVGKLRPSVVLYNEMHRDGEVV
RRDLSGADLLLVVGTSLRVPGTKRIVREFSKRGMKSIYLNLDFTRWEGVFDAWVQGDAQGFARILTEEIS---------
>tr|F8NXQ3|F8NXQ3_SERL9 Putative uncharacterized protein OS=Serpula lacrymans var. lacrymans (strain S7.9) GN=SERLADRAFT_449479 PE=4 SV=1
------------------------------RRVVKAIMKAKRLVVVCGAGISVKAGIPDFRSPDGLFQTLSGKDLFDASVFNSENSLFCQMIAQLSELS-
-QSATPTSFHRLLRTLDDR-GGLLRVYTQNIDAIESKSGLKRCIPLHGTLQTLHCQTCTHSFPLEQYLPAPPYCPECTRVGKLRPSVVLYNEMHKDGEVV
RRDLSGADVLLVVGTSLRVPGTKRIVREFAKRGIKSIYLNLDFTRWEGVFDAWVQGDAQDFASILDDEIE---------
>tr|A0A094GRV8|A0A094GRV8_9PEZI Uncharacterized protein OS=Pseudogymnoascus pannorum VKM F-4518 (FW-2643) GN=V500_01549 PE=4 SV=1
--------------------------------------KVKRVVVLTGASISTSAGIPDFRSPDGLYSNLYPEAVFDISFFRQNPAPFYMLAQELYPVRG
WEREKVIEAHGSFAS---KKGLLYMLFTQNIDCLERAAGVEKVIEAHGSFASQRCIECKTEYPDESMIGDIPHCEECE--GLVKPDITFFGESLPRFHSN
THVPAQADLLIIIGSSLSVYPFASLLDFAL-EGTLRVLLNMERVGSSRPDDVLLLGDCDGQVRRLADELG---------
>tr|G3JGP9|G3JGP9_CORMM Histone deacetylase SIR2, putative OS=Cordyceps militaris (strain CM01) GN=CCM_04691 PE=4 SV=1
------------------------------EDAVQLIARSAHIVIITGAGISTSLGIPDFRSKTGLYAKGDPQEVFDIDIFKEDPSV---FYSVAKDILP
-ATERYTPTHAFIAMLHRR-GKLLTNYSQNIDNLEVKAGVDKLIQCHGSFGTASCVQCGFQTAGEPDIGVIPKCPRCAQTGVMKPDITFFGEALDEFSRT
ENDRDKVDLVIVIGTSLKVTPVSEIVSWLPS-HIPQIYVSRQPVTH-INFDIDLLGDCDVVVAELCRRLGW--------
>tr|A0A0E9NE63|A0A0E9NE63_9ASCO Uncharacterized protein OS=Saitoella complicata NRRL Y-17804 GN=G7K_2176-t1 PE=4 SV=1
------------------------------DEVAHAVAKAKRVMVVTGAGISCNAGIPDFRSSDGLYNLIKGKDLFDISLFN-TPETTSTFYTFLRRAIL
--DATPTPTHRFIRTLKDK-SKLLRCYTQNIDGLETREGLEDVVQLHGDIHSLVCTLCQQKAPWTPELMSAPSCLHCESSGVLRPNIVLYGEEHPTLALI
NRDRRRIDCLLVIGTSLRIPGFKKLVKDAAQYGGKVVFVNLGAPSVSGVLDWWVEGDSDAWV-----------------
>tr|I6NE33|I6NE33_ERECY Uncharacterized protein OS=Eremothecium cymbalariae (strain CBS 270.75 / DBVPG 7215 / KCTC 17166 / NRRL Y-17582) GN=Ecym_5587 P
-----------------------------------QINKSRKVMVLTGAGISCNAGIPDFRSSDGLYSLYSGQDMFDISLFQEEEKVFATFMDSLHSSTI
--MAKPTRTHEFIAHLKNK-KRLLRCYTQNIDGLEEQLGLEDVVQLHGDLNSLSCTQCFKAFNWSRSWGALPPCPRCHEVGILRPNIVLYGENHPSITHG
MDAKGKPDLLIIMGTSLKVDGVKKLVKSIHERSGIVLLINNTNCNWHGIIDYQLVSDCDEWVSDLKKRIP---------
>tr|M9N1U9|M9N1U9_ASHG1 FAEL229Wp OS=Ashbya gossypii (strain FDAG1) GN=FAGOS_FAEL229W PE=4 SV=1
-----------------------------------QIGRSRKIMVLTGAGISCSAGIPDFRSSGGLYNMYSGQEMFDISLFREEEKVFATFMDSLHSSAI
--QAKPTRAHEFIAHLKNR-GKLLRCYTQNIDGLEEHLGLEDVVQLHGDLNSLSCTQCFEVFNWTRSWGELPPCPRCCAVGILRPNIVLYGENHPSITQG
MDAKGKPDLLIIMGTSLKVDGVKKLVKSIHERSGIVLLINSTTCNWHGIIDYQILAECDAWVADLKKRLP---------
>tr|G4ZQI6|G4ZQI6_PHYSP Putative uncharacterized protein OS=Phytophthora sojae (strain P6497) GN=PHYSODRAFT_506237 PE=4 SV=1
--------------------------------LAELIANSRHLVAFTGAGISTSVGIPDYRGEHGIRTKNDKSKRDGSEGDENDAK----NEAARIKIPD
FNSLVPSTTHMALYELHR-LGYLKHVVSQNVDNLHLKSGVSALTEVHGNATQAKCETCEKIYPWTG-LCDDPECVSHG-NGRLKRNVVGFDEPLGDIDLA
IDECEAADVALVLGTSLRVEPFSEMAGDYA---GSLCIVNLQPTTLDRRAGVRLFEKTDVVMEKTMQFLMKD-------
>tr|K3XAV4|K3XAV4_PYTUL Uncharacterized protein OS=Pythium ultimum DAOM BR144 GN=PYU1_G014323 PE=4 SV=1
--------------------------------LAELIAKSKHLVAFTGAGISTSVGLPDYRGDNGIRTKGVEKHSMRRGSTSSSDS----ESGKQVVIPD
FNSLVPSKTHMALYELHR-LGYLKHLVSQNVDNLHLKSGLSALTEVHGNATQAKCETCEKIYPWTG-LCDDPACVSHG-NGRLKRNVISFDEPLDDIDHA
IDECEAADVALVLGTSLRVEPFSEMAGEFA---DALVIVNLQPTTLDKRAGVRFFEKCDVVMEKTMKFLLGE-------
>tr|M4B9U7|M4B9U7_HYAAE Uncharacterized protein OS=Hyaloperonospora arabidopsidis (strain Emoy2) PE=4 SV=1
--------------------------------LANLIANSRHLVAFTGAGISTSVGIPDYRGEHGIRTKHDKVKVVHSMKEDSDAK----FEDEQGEIPD
FNLLVPSTTHMALHELHR-LGFLKHIVSQNVDNLHLKSGVNALTEVHGNATQAKCETCEKIYPWTG-LCTDSKCVSHG-NGRLKRNVVGFDEPLGDIDTA
IDECEAADVALVLGTSLRVEPFSEMAGEYA---GSLCIVNLQPTMLDRRAGVRLFEETDVVMEKTMQFLMND-------
>tr|W2NY26|W2NY26_PHYPR Uncharacterized protein (Fragment) OS=Phytophthora parasitica GN=L914_03841 PE=4 SV=1
--------------------------------LAELIANSRHLVAFTGAGISTSVGIPDYRGEHGIRTKNKKRQ-ESSDADESDVK----IEESKPIIPD
FNKLVPSTTHMALHELHR-LGYLKHVVSQNVDNLHLKSGISALTEVHGNATHAKCETCEKIYPWTG-LCDDPECVSHG-NGRLKRNVVGFDEPLGDIDLA
IDECEAADVALVLGTSLRVEPFSEMAGDYA---GSLCIVNLQTTTLDRRAGVRLFEKTDVVMEKMMQYLMND-------
>tr|A0A024GQK6|A0A024GQK6_9STRA Uncharacterized protein OS=Albugo candida GN=BN9_104670 PE=4 SV=1
--------------------------------IAELIAHSKTLVAFTGAGISTSTGLPDYRGENGIRTSRRKQP---------------------NQNTD
LNHLVPSKTHMALVELHR-IGLLHHVISQNIDNLHLKSGLSVLTEVHGNATHAICETCEKVYPWNG-LCNDRKCESHG-NGRLRRHVISFDQPLGDIDCA
IEKCEEADVALVLGTSLRVEPFCEMAGEFA---DSLVIVNLQKTTLDRRAGVRLYADCDTVMEKVMQYVMKD-------
>tr|A0A0N7L8B5|A0A0N7L8B5_9STRA Mono-adp-ribosyltransferase sirtuin-6-like protein OS=Plasmopara halstedii PE=4 SV=1
--------------------------------LAMLIANAKHLVAFTGAGISTSVGIPDYRGENGLRTKNKLQTIKSSDDIIVVPE----NEILVPIIPD
FHNLVPSPTHMALFELHR-LGFLKHIVSQNVDNLHLKSGITALTEVHGNATHAKCETCEKVYPWTG-LCDDPNCVSHG-NGRLKRNVVGFDEPLGDIDIA
IDECEAADVALVLGTSLRVEPFSEMAGEYA---GSLCIVNLQPTTLDRRAGVRLFAETDIVMEKMMQHLLND-------
>tr|R9ALE6|R9ALE6_WALI9 NAD-dependent deacetylase sir2A OS=Wallemia ichthyophaga (strain EXF-994 / CBS 113033) GN=J056_004688 PE=4 SV=1
------------------------------KRLAEILTATRRVIVMAGAGVSTGAGLPDFRSPTGLYDNLYPEAVFDVDFFREQPEP---FYALAKELY-
PGSYLPTMTHYFFRLLEVR-GILKRVFTQNIDTLERVAGVEKMVEAHGSFVRARCIDCKVVSDGAYMQGVIPRCQECS--AYVKPDITFFGEALPRFDQL
-DDLGECDLLMVLGTSLEVHPFASLIGLVE-KSVPRALLNLERVGEDGSRDIFCGGRTDNVIVELAKE-----------
>tr|I4YFI1|I4YFI1_WALMC SIR2-domain-containing protein OS=Wallemia mellicola (strain ATCC MYA-4683 / CBS 633.66) GN=WALSEDRAFT_31899 PE=4 SV=1
------------------------------KRLAEILTETKKVIIMAGAGVSTSAGLPDFRSPTGLYANLYPEAVFDIDFFREQPKP---FYALAKELY-
PGSFLPTITHYFFKLLENK-GLLKRVFTQNIDTLERVAGVDLMVEAHGSFAKARCVSCKELSDGEYMRSEIPVCQECADNAFVKPDITFFGEALPNFDKL
-DDFNHCDLLIVLGTSLKVNPFASLISFVG-GDTPRALLNLEQAGVGGSRDIFCKGKVDDVVVNLAEE-----------
>tr|K1QDT0|K1QDT0_CRAGI NAD-dependent deacetylase sirtuin-6 OS=Crassostrea gigas GN=CGI_10027454 PE=4 SV=1
--------------------------------LAEFVRASRHLVVHTGAGISTSAGIPDFRGPKGVWTLEQKGE---------KPNVSV----------T
FDNARPTLTHMALVALERA-GIVKYVITQNVDGLHSRSGFNRLSELHGNMFVEECDKCGSQFINSSALPTGNPCLKCR--GRLRDTILDWEDSLPDLELA
DKHAKEADLNLTLGTSLQIVPSGNLPLAARKKGGKLVIVNLQPTKHDSKATLKIHAFVDEVMSALCSELGI--------
>tr|A5DJ74|A5DJ74_PICGU Putative uncharacterized protein OS=Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) GN=PGUG_03325 PE=4 SV=2
-------------------------HFYSLEHVIDGLQSAKKILVLSGAGISTSLGIPDFRSSQGFYAKSDPQDVFDLGIFHTDPTV---FYSIAHMIL-
PPEHSFTPMHAFIKTLDDK-GILLRNYTQNIDNLESNVGIDRVVQCHGSFATATCVTCKNTIPGHEINKEVAYCTKCTNYGVMKPDITFFGESLPKFDTI
NEDLHECDLVISVGTSLKVAPVADIVDKVPP-SVPQILINRDPITH-CNFDVSLLGYCDDVAE----------------
>tr|L8HF60|L8HF60_ACACA Transcriptional regulator, Sir2 family protein OS=Acanthamoeba castellanii str. Neff GN=ACA1_153540 PE=4 SV=1
--------------------------------LAGMIRDSKHCVFFTGAGVSTSAGIPDYRGPEGVWTLKA-----TGGQ--RKT-----------KAVP
MLSALPTVTHMAMVKLHDV-DRMHYLVSQNVDGIHRKSGIQRLCELHGNSNLEVCCWCGKEYMRDFDTETGRRCTGCG--GPLLDTIINFGENLPDLERA
YDECDKADLIVCLGSSLTVSPANDLPKRVAKRGGNLVIVNLQRTPLDSLSTLRIHGRTDEVMKGVMEELGI--------
>tr|H1VGP9|H1VGP9_COLHI Uncharacterized protein OS=Colletotrichum higginsianum (strain IMI 349063) GN=CH063_10247 PE=4 SV=1
-----------------------PQDYIHLENIACLIDTALRVVVVTGAGISTKAGIPDYRSKNNNSR--YRRSLFHSSVFS-DPEKFYKEVTRMHQMAK
--DANPTETHHFINDLHRA-GKLVRYYTQNIDCLEDKVGLCECVLLHGSVHCLQCSFCCKVYSWDDDDGKEPFCPGCAKVGTLRPNIVLYGEEPQFIEVI
RDLHQRPDILLIMGTRLTTYGVKYLIRVFHEQNGKVVYVNLTKPAWDNVIDYWAEQECDI-------------------
>tr|A0A0C3HE37|A0A0C3HE37_9PEZI Uncharacterized protein (Fragment) OS=Oidiodendron maius Zn GN=OIDMADRAFT_165156 PE=4 SV=1
-----------------------PEVDFHMQEVADTIGKSKKVVVVTGAGISTNCGIPTNFDSSGSSRPFKGRDLFDSIIWA-DAYSFYMFITSFRQKND
--VKSTSPTHKFIRTLRDG-GRLVRNYTQNIDSLEEREGLAECVQLHGSLVSLRCGLCGKLSRWDEAEGQAPDCPSCTEVGRLRPDIVLYGEEPSLVPLV
YDLGLGPDVLLIMGTSLKVHGLKILVKEFHTKGGKVIFVNRTKPEWSDVIDYWVECDCDA-------------------
>tr|A0A066VK87|A0A066VK87_9HOMO Uncharacterized protein (Fragment) OS=Rhizoctonia solani AG-8 WAC10335 GN=RSAG8_07212 PE=4 SV=1
-----------------------------MNTLRGSTETGSEA-VVDRIDFRSQDGLYRMST-AARAENTNIMALLSALSLK-DSTKLNRFIYDFFAEAV
--TAEATRAHKMIQMMHSC-KILLRYYTQNIDGIDDQLGIPQFVQLHGSVRWLKCTLCNWGEPLSNLWGSVLHCPVCPTPGIVRTAVVLYDEEVYSINCF
QDISQKPDLLLVMGTSLSSIRSNSLIQLVHQANGLSIFMNTAPP-TTRFFDYHLAGNLED-------------------
>tr|M2LB35|M2LB35_BAUCO Uncharacterized protein OS=Baudoinia compniacensis (strain UAMH 10762) GN=BAUCODRAFT_333228 PE=4 SV=1
-----------------------PATADMLQTVARQLLNKRQIIVFTGAGISTAAGISCFQGPYANPQ---ARMMLEA--FQ-LNNFFWTFITELRQQCK
--GKRPTVFHRMIDGFSQR-QQLKWTFTQNIDGLERLCGHLKVTYLHGRLDQLRCTKNAAHKT-----GVYGECPVCIEVGRLRPDIVLYGEDPESIEQI
MKLAPQADALIIAGTSMTIAAARNAVETLGLEGSEVFWVNLQRVK-EHLIDVPLLTVLDM-------------------
>tr|A0A0G4HT79|A0A0G4HT79_9ALVE Uncharacterized protein OS=Chromera velia CCMP2878 GN=Cvel_31314 PE=4 SV=1
--------------------------------------HFRSVLLMTGAGVSTNSGIPDYRSAGGMYASIDPTFVANIRLFRQNPLPLLEVK---REFLG
NGTFRPTATHMFARILHEK-GYLMRVLTQNIDGLHTAAGVEKVLEVHGSIRNCVCSECGTSFPFQNFVKGSFQCESCN--GIIRPAVVLFGESLPSFDVA
DEEVSKADLLLVAGTSLTVAPANQVPSVVPL-SCVRLVINGQRVGEDSQRDLLLEGDLDEGVAALCR------------
>tr|A9TX70|A9TX70_PHYPA Class IV sirtuin OS=Physcomitrella patens subsp. patens GN=SRT1502 PE=4 SV=1
------------------------------KHLAQLVRESKYAVVYTGAGISTAAGIPDFRGPSGVWTLQAKGKVA-------EPD----F---------
-TKLNPTLTHYVLRSFIER-GHFHYIVTQNIDSLHLRSGVEKQSELHGNYSLETCPLCDARYFWKGDLRTGRLCEADGCAGELESSVVLFGESLPEVNSA
WDHTYKADLALVLGSSLKVGPACDMPAQVGKNGGKLVIVNLQHTPFDGRASLVIHARCDDVLRLLAEELDLSEQNPS--
>tr|L8HKV1|L8HKV1_ACACA SAP domain containing protein OS=Acanthamoeba castellanii str. Neff GN=ACA1_290800 PE=4 SV=1
-------------------------------QLAKLVEASRRMVVYTGAGISTSAGIPDFRGKNGLWVRGAPKRA--------------------VVELT
--TIEPTPTHRVLAELERM-GKVHFIVSQNYDNLHIKSGFEKLAELHGNLFAEICAKCGMKYYRDYEVLTRRSCDQCD--GALRDTIVHFGEGFDVFAAA
VAKSKEADLTLCLGSKLSVTPACDMPFYCKQGEAKVAICNLQPTDKDHEADLVIHHTCDEVMTALLDILNQR-------
>tr|A0A0D2AIC6|A0A0D2AIC6_9PEZI Uncharacterized protein OS=Verruconis gallopava GN=PV09_02335 PE=4 SV=1
------------------------------AKLLKVLHKRRKIVVVAGAGISVSAGIPDFRSSTGLFKTLSGKDLFDASVYKDGNS-TTSFHAMIRNLAT
TKDAQPTPFHHLLATLAQE-GRLLRLYSQNVDGIDTSLKWPKTIQLHGTLEHMTCTKCHRISEFKPELFSPPPCGNCEEIGVLRPRMVLYNEHPDDIGVK
ADLRTRPDALIVVGTTLKVPGVRRIVKEMRDKDGVTIWINNDPPPADYEWDLIVQGPCDLVA-----------------
>tr|R7Z000|R7Z000_CONA1 Uncharacterized protein OS=Coniosporium apollinis (strain CBS 100218) GN=W97_06666 PE=4 SV=1
------------------------------RRLIKALHNKRKIVVVAGAGISVSAGIPDFRSSKGLFRSLSGKDLFDASVYRDGTS-TSVFHDMVRELSH
TKSAKPTAFHHLLATLAKE-GRLLRLYSQNVDGLDTCLPWPKTIQLHGGLDNMVCSKCNDVQPFQAALFVPPLCGVCEAVGKLRPRMVLYNEHPDDIGTR
ADLKTYPDAVIVAGTTLKVPGVRRIVREMRNRDGLTVWVNNDPEPSDLCWDLVVTGPCDEVA-----------------
>tr|R1EWE5|R1EWE5_BOTPV Putative sir2 family histone deacetylase hst4 protein OS=Botryosphaeria parva (strain UCR-NP2) GN=UCRNP2_1183 PE=4 SV=1
------------------------------DVLLKVLHKKRKIVMIVGAGISVAAGIPDFRSSKGLFSTLSGKELFDASVYRDPDT-TATFHEMVRSLSQ
AKSAKPTAFHHLIATLADE-GRLLRLYSQNVDGIETSLEWPKTVLLHGGLEKMVCAKCNDVTDFEPNLFIPPPCKACEEIGLLRPRMVLYNENPDDIGTA
ADLRTRPDAVIVVGTTLKVPGVRRITREMRDKDGLTVWINNEPEPKDLCWDLVVRGPCDAVA-----------------
>tr|R0I9P0|R0I9P0_SETT2 Uncharacterized protein OS=Setosphaeria turcica (strain 28A) GN=SETTUDRAFT_43991 PE=4 SV=1
------------------------------QRLLTVLHKKRKIVVIAGAGISVSAGIPDFRSATGLFNTLSGKDLFDASVYQDDTS-TSTFHDMVRTLSH
TKSAQPTAFHHLLATLAQE-GRLMRLYTQNVDGIDTSLPWPKTVQVHGGLDYMSCSKCHAVTPFDAEKFSPPPCPSCVQIGRLRPRMVLYNEYPDDIGAS
YDMRMRPDAVIVAGTTLKVPGVRRIAREMRDRDGVTVWLNNDPEPVDLKWDLVVKGPCDEVA-----------------
>tr|Q0UMU7|Q0UMU7_PHANO Putative uncharacterized protein OS=Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) GN=SNOG_06917 PE=4 SV=1
------------------------------QRLLNVLHKKRKIVVIAGAGISVSAGIPDFRSATGLFNSLSGKDLFDASVYQDDNS-TSTFHDMVRTLSQ
TKSAQPTAFHHLLATLAQE-GRLMRLYTQNVDGIDTSLPWPKTVQVHGGLDYMVCSKCHDLAPFDADMFTPPPCPTCVEIGRLRPRMVLYNEHPDDIGAA
ADMRLRPDAVIVAGTTLKVPGVRRIAREMRDKDGVAVWINNDPEPLELVWDLVVKGPCDEVA-----------------
>tr|A0A010S511|A0A010S511_9PEZI Sir2 family protein OS=Colletotrichum fioriniae PJ7 GN=CFIO01_11097 PE=4 SV=1
------------------------------ARLVSALKKRKKIVVIAGAGISVSAGIPDFRSKTGLFATLSGKHLFDASVYKHDSS-TEKFHKMICDLAT
VKAAKPTHFHHLLASLAAE-NRLLRLYSQNVDCIDTNMEWPKTIQLHGSVDHMVCSKCSDIKALETELFEAPLCKTCEDIGRLRPRMVLYNEFPDEIGSS
VDLKSRPDAVIVVGTSLKIPGVRRLVKELRSRDGFTAWINTDSEPQDFCWDLVVRGKCDDVA-----------------
>tr|G8BMP5|G8BMP5_TETPH Uncharacterized protein OS=Tetrapisispora phaffii (strain ATCC 24235 / CBS 4417 / NBRC 1672 / NRRL Y-8282 / UCD 70-5) GN=TPHA0A00880 PE=4 SV=1
------------------------------SSLVDILERSKNIIVLTGAGISTSLGIPDFRSSQGFYSQDDPQDVFNLNIFRQNPSV---FYNIA-NMVL
PPENIYSPLHSFLKLLQDK-NKLLRNYTQNIDNLESYAGLDKMIQCHGSFASASCFTCGYSMPGNKINREIPLCPKCINYGVMKPDITFFGEALPRFEQI
SKDIKQCDLLITIGTSLKVAPVSEIVNMLSK-HVPQILINKDPVNH-ANFDLSLLGYCDDVVAYISKLL----------
>tr|F0XMI9|F0XMI9_GROCL Cytoskeleton assembly control protein OS=Grosmannia clavigera (strain kw1407 / UAMH 11150) GN=CMQ_5961 PE=4 SV=1
-------------------------RYNSVDDAVQLLQKSQNIIVLTGAGISTSLGIPDFRSKTGLYSRSDPQEVFDINVFREDPSI---FYSVARDILP
-ATDRFTPTHAFIAMLQQR-EKLLTNYSQNIDNLEAKAGIDKLVQCHGSFATASCVACGYRVDGESIAGDIPHCPECAAVGVMKPDITFFGEPLDEFQRL
TEDRDRADLVVVIGTSLKVAPVSEVVPFMPP-HVPQIYISRTPVHH-INFDIDLLGDCDVVVAELCRRLGWDLQH----
>tr|A0A0P4W8L8|A0A0P4W8L8_9EUCA Uncharacterized protein OS=Scylla olivacea PE=4 SV=1
---------------------------------AGWMRESKHTVIHTGAGISTAAGIPDFRGPNGVWTLEK-EGL--------KPDV----------NIS
WDDARPTLTHMAIVSLEQR-GYVQYVVTQNIDGLHLRSGLQKLAELHGDMFVDKCNLCQRQFVRSSAASEGKACPRCR--GKLHDNILDWEDGLPDLDLA
ISHSCVADLSLCLGTTLQIVPSGNIPVDTKKRGGRLVICNLQPTKQDRHADLIINTYVDILMKRLLELL----------
>tr|U1HWN9|U1HWN9_ENDPU Uncharacterized protein OS=Endocarpon pusillum (strain Z07020 / HMAS-L-300199) GN=EPUS_06215 PE=4 SV=1
------------------------------KDAIALVQHSKNIMVITGAGISTSLDIPDFRSRGGLYSTEDPESVFSRDTFEQDPRP---FFSVAAKILP
PTDGRYTPAHAFLRLLQDK-GKLLTLYTQNIDGIDLTAGIDKLVQLHGSFETATCISCAHRVRGEERKCEVPICTECARVGIMRPDIVFMGEPPPYLKRF
QRDCAQVDLLIVMGTSLPVEPVNTMPNKIPP-AVPQIYIGKNEMSLEGDFDIQLLGECDVIA-----------------
>tr|F9FTP0|F9FTP0_FUSOF Uncharacterized protein OS=Fusarium oxysporum (strain Fo5176) GN=FOXB_09771 PE=4 SV=1
-------------------------------EIVALIKKSKHFIVFTGAGVSTSAGIPDFRGPEGAWTLRA-QGRA-------RT-------GKATST--
-LQAIPTPTHMALVELQNQ-GVLKYLVSQNCDGLHRRSGIDRISELHGNSNRECCKDCGKEYIRDFDHRTGRKCTACG--GNLLDTIINFGEFLPPLKLA
QSHAKKADLCIALGSSLSVPPASGIPETCGKRKSKLITCNLQETFMEGIADMHIWAESDVLMTRVMNRLG---------
>tr|A0A0D2MSX8|A0A0D2MSX8_9CHLO NAD-dependent deacetylase sirtuin 2 OS=Monoraphidium neglectum GN=MNEG_2330 PE=4 SV=1
--------------------------------------------------VSVSAGIPDFRTPTGLYSQLTPEAVFEMNYFRRNPKPFHILAKE---LF-
PGNFAPTPAHVFMKLLLDK-GLLLRVYTQNIDSLEHQAGLDRVVAAHGNFDTAHCIKCGRQHSVDYEADKICHCSSCG--GLVKPDIVFFGESLPFYDMA
EVDFPRADLLIVLGTSLVVHPFASLIGCVG-GSVPRLLINRERVGEDEYRDVLHLGDCDDGCRRLAAL-----------
>tr|F5HMW1|F5HMW1_ANOGA AGAP001220-PB OS=Anopheles gambiae GN=AgaP_AGAP001220 PE=4 SV=1
-------------------------------KLAQAIAKANHLIVYTGAGISTSAKIPDYRGSQGIWTLLQGKDIGE--------------Y-----DL-
-SLADPTYTHMALFELHRR-GILKHVLSQNCDGLHLRSGLPSLSEVHGNMYVEVCKQCKPEYWRLFDTKTNRRCRRCG--GPLIDTIVHFGERLWNWAGV
TPHTEKTDLILCIGSSLKVLRKYTWLWATDKKRPKIFIINLQWTPKDKVSTLKINGKCDQVMMLVMKHLN---------
>tr|B3LXN3|B3LXN3_DROAN Uncharacterized protein, isoform A OS=Drosophila ananassae GN=Dana\GF16275 PE=4 SV=1
-------------------------------QLANIISQAKHLVCYTGAGISTAALIPDYRGSQGIWTLLKGQEIGE--------------H-----DL-
-SSANPTYTHMALYELHRR-RILHHVVSQNCDGLHLRSGLPSLSEIHGNMYVEVCKSCRPIYWRQFDTKTHRLCHRCS--EPLYDTIVHFGERLWNWAGA
TANADRADVILCLGSSLKVLKKYTWLWQMDRQRAKICVVNLQWTPKDSIASIKINGKCDRVMAQLMHLLH---------
>tr|A0A0M4ENE3|A0A0M4ENE3_DROBS Sirt7 (Fragment) OS=Drosophila busckii GN=Dbus_chr3Rg951 PE=4 SV=1
-------------------------------KLANIISQAKHLVCYTGAGISTSALIPDYRGSKGIWTLLKGQDIGE--------------H-----DL-
-SRANPTYTHMALYELHRR-RLLRHVVSQNCDGLHLRSGLPSLSEIHGNMYVEVCKQCKPAYWRQFDVKTHRLCHRCS--EPLYDTIVHFGERMYNWTSA
TQHAERADVILCLGSSLKVLKKYTWLWQMDRQRAKICVVNLQWTPKDNIAGIKINGKCDNVMEQLMRALN---------
>tr|A0A0A1X3W6|A0A0A1X3W6_BACCU NAD-dependent deacetylase sirtuin-7 OS=Bactrocera cucurbitae GN=Sirt7 PE=4 SV=1
-------------------------------DLAAIIAQSKHLICYTGAGISTSALIPDYRGSKGIWTLLKGEDIGE--------------H-----DL-
-SAANPTYTHMALYELHRR-RLLRYVVSQNCDGLHLRSGLPSLSEIHGNMYMEVCKHCKPVYWRLFDTKTNRLCHRCS--EPLYDTIVHFGERLWNWAGA
CHHAEKADVILCLGSSLKVLKKYTWLWQMDKQRAKICIVNLQWTPKDSIATIKINGKCDRVMEILMRALN---------
>tr|K1R7D0|K1R7D0_CRAGI NAD-dependent deacetylase sirtuin-7 OS=Crassostrea gigas GN=CGI_10013956 PE=4 SV=1
------------------------------QQLAEAIRTSNSVVVYTGAGISTAASIPDYRGPNGVWTLLQKGQ---------QPEA---------QDLS
--DAEPTITHMCITQLYRN-GHVKHVVSQNCDGLHLRSGFPFLSEVHGNMYIEICNHCKPEYIRLFDVTTDRSCHSCG--KPLKDTIVHFGEKPYRWKEA
AKAANNCDIILCLGTSLKILPCLWCMDRRLQKRPKLYIVNLQWTPKDDTATLKINGRCDDVMRRIFEILR---------
>tr|A0A0L8HEZ4|A0A0L8HEZ4_OCTBM Uncharacterized protein OS=Octopus bimaculoides GN=OCBIM_22016988mg PE=4 SV=1
------------------------------DQLAEAIKKSKGICVYTGAGISTAASIPDYRGPNGVWTLLQKGQ---------ELKP---------QQFT
--DAEPTKTHMGLLTLYKH-GKLKHVVSQNCDGLHLRSGLSILSEVHGNMYLEMCYKCKPEYLRLFDVTTSRRCHYCK--NLLSDTIVHFGEKPYRWKEA
AAAAENCDVILCLGTSLKVVF------LKPSKRPKLFIVNLQWTPKDVCATLKINGRCDDVMDQIMKKLG---------
>tr|S7PVN2|S7PVN2_GLOTA DHS-like NAD/FAD-binding domain-containing protein OS=Gloeophyllum trabeum (strain ATCC 11539 / FP-39264 / Madison 617) GN=GLOTRDRAFT_81021 PE=4 SV=1
------------------------------QALALLIRGAQRVVVYTGAGISTSAGIPDFCGPQGVWTRQE-EGI---DA---------------RVAI-
PDTTSPTPAHMALVRLVE-LGKVSLVVSQNMDGLHLRSGIARLAELHGNRNVEVCTLCGMGYFRRKDHQTGRRCDVCA--GPLRDSIVQFGESLPAWARS
VEESKRADLGIVLGSSLLVSPASDVPLALVRAGTPLAIVNLQRTPLDASAALRLGAPTDAVMAGVLRALGEDV------
>tr|E1F5B1|E1F5B1_GIAIA NAD-dependent histone deacetylase Sir2 OS=Giardia intestinalis (strain P15) GN=GLP15_646 PE=4 SV=1
------------------------------EAFIYQLRRARKVIFLVGAGISVSAGIPDFRSKNGIYNRQKPTDMFNLDFFRNNPIPFYRFCPEI---FP
GPQFKPTVVHLFMRLLEKR-GQLQRIYTQNIDCLEVQAQIKYIINCHGSFHTFACIDCGAKFPMELDVEGDDLCSNSGQRGILKPQIIFFGEKLSDLEEF
DDDSSVADMFIAIGSSLRVKPVSGILGKLP-RTVPQVLINLESVGRPHNWDLELLGDCDIIMRYLLTEL----------
>tr|R1CJV5|R1CJV5_EMIHU Uncharacterized protein OS=Emiliania huxleyi GN=EMIHUDRAFT_195308 PE=4 SV=1
------------------------------AALAELMRGSRHILFCTGAGISTPAGLRDYRGPDGIWTEAQASGLVVGEGMVDSP---WDETMF-R-RM-
-PAARPTFAHRAIAQLGED-PLVKHVITQNEDGLHRRSGVPRLSELHGSAFVEVCGNYASSDESSSSEARERRPAGCG--ALTRPYKLAVGFPVHKLRAA
KEHMQLADLVVAWGTSMSI-----LANYFDP------WHRESRALDEDLAELKIEADVDEVAAKLLRELGL--------
>tr|A0A0E9NMJ5|A0A0E9NMJ5_9ASCO Uncharacterized protein OS=Saitoella complicata NRRL Y-17804 GN=G7K_5213-t1 PE=4 SV=1
-------ALSRFLSKRQKLA--QYNTV---SDAVELIRNAKNIIVLTGAGISTSLGIPDFRSDTGIYAKNDPQEMFDIDVFRSDPSIFYSFAR---LILP
PSSSRFTPTHAFIRLLQDK-GKLLTNYTQNIDGVESVAGIEKLVQCHGSFGGAGCVTCGYKCPGEGDIGRIPKCPLCLELGVMKPDITFFGEPPPTFSRL
TPDAECCDLLIAIGTSLKVSPVSEILGLLPP-HVPAVYVGIEAVKH-VEFDVQLLGV----------------------
>tr|A0A087TQH4|A0A087TQH4_9ARAC NAD-dependent deacetylase sirtuin-7 (Fragment) OS=Stegodyphus mimosarum GN=X975_10477 PE=4 SV=1
------------------------------AQLSQALKESSFTVVYTGAGISTSAEIPDYRGPDGIWTLLQQKEI--------------KF-----KDLS
--LAEPTFTHMALKQLHKE-GFISHIVSQNCDGLHLRSGLSALSEVHGNMFIEVCPKCKPQYIRLFDVKTGRFCKKCG--TELHDTIVHFGEKLWNWKGA
VKAVSKADLILCLGTSLRVLRRYHGLWMTHIKRPKLYIVNLQWTSKDTQATLKIHGKCDEVMKQVTTNLGVN-------
>tr|A0A023GJ54|A0A023GJ54_9ACAR Putative class iv sirtuins sir2 family (Fragment) OS=Amblyomma triste PE=2 SV=1
------------------------------KELANAIAEAHHLVVYTGAGISTAACIPDYRGPAGVWTLLNKHQLP-------------DV-----QDLS
--QACPTFTHMALAQLQRA-GHVKHVVSQNCDGLHVRSGLSCLSEVHGNMFLEVCPRCKPQFFRLFDVRTGRQCPACS--AELVDTIVHFGETLWNWKGA
GRAADRCDAILCLGTSLKVLRRYRCLWGLDRDRPKLYIVNLQWTPKDESAVLKINGRCDDVMRTVMEHLQLT-------
>tr|G0WCA1|G0WCA1_NAUDC Uncharacterized protein OS=Naumovozyma dairenensis (strain ATCC 10597 / BCRC 20456 / CBS 421 / NBRC 0211 / NRRL Y-12639) GN=NDA
----------------------------------KLLNKSKRIIVLSGAGISCNAGIPDLDHQMVLYESVSGKEMFDISLFRDELKVFAAFMEKLYSNVK
--LAQPTKTHKFIAHLKNR-NKLLRCYTQNIDGLEEILGLEDVVQLHGDLNSLACTRCYHNFPWSRYWGQLPMCPECERVGVLRPNIVLYGENHPSITQG
LDLSGKPDFFIIMGTSLKVDGVKKVVKQMHERGGLVLLVNKTNIGWSGVIDYQIMCDCDEWVEYLEEQLPD--------
>tr|G0VHT7|G0VHT7_NAUCC Uncharacterized protein OS=Naumovozyma castellii (strain ATCC 76901 / CBS 4309 / NBRC 1992 / NRRL Y-12630) GN=NCAS0G00840 PE=4 
----------------------------------KLLNKSRKIIVLTGAGISCNAGIPDFRSSKGLYESVSGKEMFDISLFRDEVKVFATFMEKLYANVK
--LAQPTKTHKFIAHLKDR-NKLLRCYTQNIDGLEENLGLEDVVQLHGDLNTLACTRCFHTFPWNRFWGELPTCPECERIGFLRPNIVLYGENHPSISQG
LDILGRPDFFIIMGTSLKVDGVKKVVRQMHERGGIVILINKTSVGWNGVIDYQIWSDCDTWVTYLEDMIPD--------
>tr|A0A0P5W0T8|A0A0P5W0T8_9CRUS NAD-dependent protein deacetylase sirtuin-6 OS=Daphnia magna PE=4 SV=1
-----------------------------------LFAECTAVVMHTGAGISTPAGIPDFRGPKGVWTLEKK-GL--------KPQIN----------VS
FDDAEPTFTHMAIIALFQK-NFLHYVVSQNIDGLHLKSGLSKLSELHGNMFIGQCSLCSRQYIRRKAVTLPVDCPSCR--GKLHDTILDWEHELPDLGLA
DIHSNVADLSICLGTTLQIVPSGTLPLATKRKGGRLVIINLQPTKWDKKADLVINTYVDDVMKLLLKELN---------
>tr|V2XQ59|V2XQ59_MONRO Sir2 family histone deacetylase hst4 OS=Moniliophthora roreri (strain MCA 2997) GN=Moror_12365 PE=4 SV=1
------------------------------TQVIKSILKARRIVVICGAGISVKAGIPDFRSPEGLFQSENPKDLFDASVFNSEQTT-ALFCQM-ISRLS
SKEAEPTPFHRSLKALDDS-GKLLRVYTQNIDAIESKCGLPRCIPLHGTLQTLHCQVCTHSFLLEDYISVPPDCPECTSVGRLRPSVVLYNEAHKDGEGV
GEDVSGADLLLVVGTSLRVPGTKRMVREFAKHPLKAIYLNLDFTRWEGVFDAWLQGDAQTFAEMLQEEIRK--------
>tr|M2R5H2|M2R5H2_CERS8 Uncharacterized protein OS=Ceriporiopsis subvermispora (strain B) GN=CERSUDRAFT_117653 PE=4 SV=1
------------------------------KKVIKAIMKARRIAVVCGAGISVQAGIPDFRSSEGLFQTDNPKDLFDASVFCSENTT-SLFCQM-IAQLS
SQAAAPTAFHQLLRALDDR-GRLLRVYTQNIDALESKSGLPRCIPLHGTLESMHCQTCTHSFPLRDHLPVPPYCPECTAVGKLRPSVVLYNELHKDGEEV
GDDIAGADLLLVVGTSLRVPGTKRIVREFSKAPIKTVYLNLDFTRWEGVFDVWVRGDAQAFAQLVREEMAG--------
>tr|A0A0C3RZX8|A0A0C3RZX8_PHLGI Uncharacterized protein OS=Phlebiopsis gigantea 11061_1 CR5-6 GN=PHLGIDRAFT_127294 PE=4 SV=1
------------------------------KRVVKAILRAKRIAVLCGAGISVQAGIPDFRSETGLFQTENNRDLFDASVFNSEATI-MLFCKM-IAKLA
SKLAQPTPFHRMLRTLDDR-GRLLRVYSQNIDALEQKAGLPRCIPLHGTVQNMHCQTCLHSFALENYLEELPICPECSQVGKLRPSVVLYNELHKDGEEV
GEDLMGADLLLVVGTSLRVPGTKRMVREFSKAPIKTIYLNLDFTRWEGVFDVWIRGDAQEFAQLVQEEIER--------
>tr|S8E9S8|S8E9S8_FOMPI Uncharacterized protein OS=Fomitopsis pinicola (strain FP-58527) GN=FOMPIDRAFT_1119769 PE=4 SV=1
------------------------------QKVIKAIMKARRIAVVCGAGISVNAGIPDFRSSEGLFQTDNPRDLFDASVFNSEGTT-SMFCQM-IAQLA
SEVALPTSFHHLLRALDER-RRLLRVYTQNIDALEQKCGLPRCIPLHGTLQQMHCQICTHSFPLRDYLPKPPYCPECNAVGKLRPSVVLYNEMHKDGEEV
GDDIAGADLLLVVGTSLRVPGTKRIVREFSKPPIRTVYLNLDFTRWEGVFDVWVRGDAQEFARLVLEEMKR--------
>tr|A0A0B7F9P6|A0A0B7F9P6_THACB NAD-dependent histone deacetylase HST3 OS=Candida albicans (Strain SC5314 / ATCC MYA-2876) GN=HST3 PE=3 SV=1 OS=Thanatephorus c
--------------------------------IALAVAKARRIVVVTGAGISCSSGIPDFRSGDGLYNLYKGRDLFDAALF-RDPGVFYSFMAELKTQID
--SAHPAPVHDFLAMLDDK-GKLLRSYTQNIDGLEERAGLAKNVQLHGDIHRVRCTLCSASYPCSPNHGVPPDCDKCG---TLRPAIVLYDEPHPLGDQT
SDLGKKPDLLIVMGTSLKVHGLRLLVKSFHSSLYNVLFVNRTPPPWTSIIDYHVQGDTDAWVSHVLGEW----------
>tr|N6TUQ0|N6TUQ0_DENPD Uncharacterized protein (Fragment) OS=Dendroctonus ponderosae GN=YQE_01808 PE=4 SV=1
-----------------------------------WIEEAKHVVVHTGAGISTAAGIPDFRGPNGVWTLEKE-G--------KKPNIN----------IS
FNDAVPTKTHMALKYLIEK-EYIHYVISQNIDGLHLRTGLTHLAELHGNMFIGQCDTCDSQFVRTTATSLEEFCKSCR--GKLKDTILDWEADLPDLEMS
DYHSSLADLNICLGTTLQIVPSGNLPLRCKKYGGKVVIVNLQPTKHDKKADLIINTYVDNVIEKVMKHLN---------
>tr|R4XIZ9|R4XIZ9_TAPDE NAD-dependent deacetylase hst4 OS=Taphrina deformans (strain PYCC 5710 / ATCC 11124 / CBS 356.35 / IMI 108563 / JCM 9778 / NBRC 8474) GN=TAPDE_003558 PE=4 SV=1
--------------------------------IADNVLDAKRIVFVSGAGISCSAGIPDFRSMNGLYSTIKGKDLFDVSLFQSTTELFYRYMANLRTKTL
--AATPTATHRLLKTLRER-KKLLRAYTQNIDGLEARAGLNDTIQLHGDIHTLKCFLCAETFDYSDAAGEAPDCPTCADIGTLRPDIVLYGEQHPAGEQI
ADLKKKPDCLLIAGTSLKVPGLKRLVKDFHDQGGLVILVDLTEPAWMDVIDYHVQGRSDDFVALL--------------
>tr|A0A0J1B881|A0A0J1B881_9TREE DHS-like NAD/FAD-binding domain-containing protein OS=Trichosporon oleaginosus GN=CC85DRAFT_257749 PE=4 SV=1
----------------------------------LRVVKARRVVVVSGAGISCSSGIPDFRSGDGLYSLYTGKDLFSSGLF-STPETTSIFYTFIAELIA
CQAAEPTRTHHFIRRLEAK-GKLLRSYTQNVDGFERRLGLTRNVELHGDLGRVRCVLCSADFEACEQEGEAPSCPACEEVGTLRPSIVLYDEAHPLILQA
HDMKRRPDVLLIMGTSLKVHGLKHLIKDFHERKGIVVFVNATAPNWEGVIDYHVQGPTDDWVDLVQED-----------
>tr|J6EM72|J6EM72_TRIAS Member of the Sir2 family of NAD(+)-dependent protein deacetylase OS=Trichosporon asahii var. asahii (strain ATCC 90039 / CBS 2
----------------------------------CRVSKAKKVVVVSGAGISCSSGIPDFRSADGLYALYNGKELFSSGLF-MNPNTTSIFYTFIAELLA
CQAANPTRTHHFIHRLERK-GKLLRSYTQNVDGFERRLGITRNVELHGDLGRVRCVLCYTDYEARQEEGEAPECPACQAIGSLRPSIVLYDEPHPLILQT
YDMRRGPDVLLIMGTSLKVHGLKRLVKDFHEKKGVVVFVNATAPSWEGVIDYHIEGQTDAWVERFEED-----------
>tr|B6K5R3|B6K5R3_SCHJY Sir2 family histone deacetylase Hst4 OS=Schizosaccharomyces japonicus (strain yFS275 / FY16936) GN=SJAG_04039 PE=4 SV=2
------------------------------QPLASVLQKSKRIVVITGAGISCQAGIPDFRSSTGLFKTLSGKEMFDNSVYR-NIEIFHEMIKQLYEL--
SKNANPTDFHYFLAKLAKE-SRLLRLYTQNIDYLETRLEGPLTIALHGTLEMVSCTKCGYIQKFDPSFFGLTACPECRIEGCLRPRIVLYNESHPDIGSV
QDLKSKPDCLIIAGTSCKIPGVKRIIKQMRRQKGSVVWMNHDPPNFDHLCDVIVTGDCQTAVKE---------------
>tr|A0A0D2AT17|A0A0D2AT17_9EURO Uncharacterized protein OS=Exophiala spinifera GN=PV08_12104 PE=4 SV=1
------------------------------LRECSSFLRTARVVVVTGAGISRSCGIPDFRSPGGLFSQTSGKDLFQVDLLR-TVRVFMQFTAALYTRL-
GALEEASATHWFLRCLHDR-GQLIRCYTQNIDGLEARVGLCPIIQLHGDVRFVRCTICDHRSSWTDAALTSITCPRCLDCGSLRPDILLYGETHSNLQLA
NDDGLRPTALLIMGSALRVPGCKDLVKRFSKQNGRVISVNPTRPSWGQIIDDHFSMECDDWVGD---------------
>tr|A0A0L0HTT9|A0A0L0HTT9_SPIPN Uncharacterized protein OS=Spizellomyces punctatus DAOM BR117 GN=SPPG_00465 PE=4 SV=1
------------------------------SKVATALWRSKRCVVVTGAGISVSGGIPDFRSADGLYNLYKGKDLFDATLF-KDPVLFYTFMAELKQVIN
--QANTTPTHHFVKDLDER-GQLLRCYTQNIDCLELRLQSARIVQLHGDLDHVVCTICQAMFDFSDDFKGPPSCPTCVEIGTLRPNIVLYNEHHSRGDTA
YDVKKRPDMLIVMGTSLKVVGIKRLVKDLAKRNGQVVFINNTEIEWDDVFDYHILGKTDDVVAELEQEMK---------
>tr|A0A078B6Z8|A0A078B6Z8_STYLE Silent information regulator protein sir2 OS=Stylonychia lemnae GN=Contig6034.g6456 PE=4 SV=1
-------------------------------KAAEYLKNCKNIMILTGAGLSAASGIPTFRGSNGFWTKEDPTEILTLKCFDQNPSIAWQWHYDFIDLMK
--TCKPNNGHQAIYELQKFSKLNTLLVTQNIDNFHTVTGTEDVLEVHGNVLYMRCYKCNDFYLSPPPISHVPLCQKCE--SVMKPHCMFFDESYEELYTV
SEYLDRLDGLIVIGTALQTSLANQIVQKTLALEVPVVEINPEPCVK-NGFGVIVKESSLTSLPTIVKQLISL-------
>tr|R0JJC8|R0JJC8_SETT2 Uncharacterized protein OS=Setosphaeria turcica (strain 28A) GN=SETTUDRAFT_181656 PE=4 SV=1
--------------------------------------RAGSTLLLTGAGISVASGLADYRGTNGTYTLYRP---IYFSEFCASHETRKRYWA--RSFIG
WERARPNRTHEACADLGRL-GVVERVITQNVDSFHPTAHPLPTTELHGYLRSLVCLTCRNEYSRRAQVFRYPACPVCLEGGVLKPAVIMFGESIPTKAAA
EQAVDAAGRILVLGSSLATYSAWRLVKKAKEMHLPIGILNIGGVRGEDTFALRLSDNAEILLPQVY-------------
>tr|A0A0F4Z9N8|A0A0F4Z9N8_9PEZI Uncharacterized protein OS=Thielaviopsis punctulata GN=TD95_002453 PE=4 SV=1
----------------------------------------QSTVVLSGAGLSVASGLADYRGENGTYRVYRP---IFYNEFVANHAARKRYWA--RSFLG
WQNAAPNPGHYAVGDLGRM-GFVNAVITQNVDSFHHEAHPLQTTELHGYLRAVKCITCKSEFPRDVDMFRYPPCPRCLEGGVLKPAVVQFGENIRVKDTA
QSHIDNAGKLLVLGTSLATYSAWRLARSAKERGMPIAIVNIGGVRGEEIFGVRVELPTHILLPQLV-------------
>tr|N1QCQ9|N1QCQ9_PSEFD Uncharacterized protein (Fragment) OS=Pseudocercospora fijiensis (strain CIRAD86) GN=MYCFIDRAFT_2219 PE=4 SV=1
------------------VDVEQQAQL---DRLLNVLHKRQKIVVIAGAGMSVSAGIPDFRSSQGLFRSLSGKHLFDASVYKDDVSSFHDMVSTMSRLT-
-KDAKPTAFHHMLATIAQE-DRLLRLYSQNVDGIDTSMDWPRTVQLHGGLDYMVCSKCHELSDLDPSLFVPPLCSRCEEIGRLRPRMVLYNEHPDDIGAT
KDDLKRPDAVIVVGTTLKVPGVRRIVREMCRRGGVAIWINSDPPPIADCWDIIVRGPCDEVA-----------------
>tr|A0A074Z3I3|A0A074Z3I3_9PEZI Uncharacterized protein (Fragment) OS=Aureobasidium subglaciale EXF-2481 GN=AUEXF2481DRAFT_61265 PE=4 SV=1
------------------LRPDEKTQL---DRVLNVLHKRQKIVVVAGAGISVSAGIPDFRSSTGLFNSLSGKDLFDASVYKDASSSFHQMVREMSHMT-
-KSAQPTLFHQMLATLAQQ-DRLLRLYSQNVDGIDTSLEWPKTIQLHGGLDKMVCSKCHELSDFHADLFVPPVCTNCEEVGMLRPRMVLYNEHPDDIGTT
REDLKRPDAIIVVGTTLKVPGVKRIVREMCRKDGVAIWINAGSEPSGDCWDIVVKGTCDEI------------------
>tr|F9X1M4|F9X1M4_ZYMTI Uncharacterized protein (Fragment) OS=Zymoseptoria tritici (strain CBS 115943 / IPO323) GN=MYCGRDRAFT_54552 PE=4 SV=1
------------------IHPDEQDQL---DRLMQVLHKRQKIVVIAGAGISVSAGIPDFRSSGGLFRSLSGKNLFDASVYRDDNSSFHDMVSTMSKLT-
-KDAKPTAFHHMLATIAQE-DRLLRLYSQNVDGIDTSLDWPRTVQLHGGLSKMVCSKCHELSDLDPELFIAPLCPRCEEIGRLRPRMVLYNEHPDDIGAT
KEDLKRPDAVIVVGTTLKVPGVRRIVREMCRRGGVTVWINNDPPPVSDCWDIIVNGTSDAVA-----------------
>tr|N1QJ59|N1QJ59_SPHMS DHS-like NAD/FAD-binding domain-containing protein (Fragment) OS=Sphaerulina musiva (strain SO2202) GN=SEPMUDRAFT_32066 PE=4 SV
------------------VHPDQQRQL---DRLVNVLHRRQKIVVIAGAGISVSAGIPDFRSSQGLFRTLSGKDLFDASVYKDDASSFHDMVNTMSRLT-
-KDAKPTAFHHMLATIAQE-DRLLRLYSQNVDGIDTGLEWPRTVQVHGGLDKMVCSKCHDLADLEPTLFVPPTCTRCVEIGRMRPRMVLYNEHPDDIGAT
KDDLKRPDAVIVVGTTLKVPGVRRIVREMCRKGGVAIWINSDPPPITDCWDIIVQGPCDNVA-----------------
>tr|A0A060T5F6|A0A060T5F6_BLAAD ARAD1B10868p OS=Blastobotrys adeninivorans GN=GNLVRS02_ARAD1B10868g PE=4 SV=1
------------------TNSTLRRDL---ALLHHVFESSRRLIVVTGAGISVYAGIPDFRSQEGLFASLSGKSMFDASVYQDDKSNFHATVRDLHKLV-
-SDAQPTPFHQYLDQISST-GRLVRLYTQNIDCLDTNLPYPRTIQLHGALNVMACSKCQWMGELKPDIFEVPDCPECVEIGKLRPRIVLYNEAPDAIGSS
EADISRPDGLVVVGTSFKIPGVRRLVRELAAR-GAAIWINTDSPSPSTTFDLIVRADCQLIP-----------------
>tr|G6DFK5|G6DFK5_DANPL Putative chromatin regulatory protein sir2 OS=Danaus plexippus GN=KGM_22599 PE=4 SV=1
-------------------------------RLARALRDAKHLVVYTGAGISTAADIPDYRGPRGVWTRLQRGEVG-------------------RVEV-
-SRAQPTFTHMALTALWAR-GSLKFVVSQNCDGLHVRAGLRALAELHGDMFAERCAACRRVYLRAFDTTTRRLCHDCG--RELRDTIVHFGERSWNWSGA
LRHAAAADVVLCLGSSLKVLPRLWRMQSAPHQRPALYIVNLQWTPKDGVAALKINARCDAVMAQVARRLRLR-------
>tr|H9J7P0|H9J7P0_BOMMO Uncharacterized protein OS=Bombyx mori GN=LOC101745061 PE=4 SV=1
-------------------------------RLARALRNAKHLVVYTGAGISTAADIPDYRGPHGVWTRLQRGEVG-------------------RVEV-
-SRANPTFTHMALTALWAR-GALKFVVSQNCDGLHLRAGLRALAELHGNMFAELCAPCRKLYLRSFDTTTRRLCHACG--TELRDSIVHFGERAWNWAGA
LRHAARADVVLCLGSSLKVLGRLWRMHSAPSSRPALYIVNLQWTPKDSVAKLKINARCDTVMRQVARRLRLR-------
>tr|A0A0D8Y1F5|A0A0D8Y1F5_DICVI Transcriptional regulator, Sir2 family OS=Dictyocaulus viviparus GN=DICVIV_05476 PE=4 SV=1
-------------------------------KLAKLLLQSKFVFVLTGAGISTSAGIADFRGPNGVWTIEKQGRVAESVD--------------------
FTLARPTYTHRALKLLEER-GIIKFLVSQNVDGLHPRSSFNRLAELHGNVFCERCEKCSRRYYRDFATYTGRTCETCR--GRLRDTTLDWEDALPDFTIA
YNYAKNADLSLCLGTSLQIKPVGDMPLLAKRNGGKMVTVNLQVTKHEKKADLAIHGLVDDVMTRVLNYLGISLD-----
>tr|A2DZ01|A2DZ01_TRIVA Transcriptional regulator, Sir2 family protein OS=Trichomonas vaginalis GN=TVAG_256040 PE=4 SV=1
-------------------------------TVINLIKNKGKTCVITGAGISAP-QLPTFRSRSGLWDVLKAPDL-SKSVFYQNPLPSWRLAANIRNLQL
NKTLKHTLAHNVLHQMVID-GYVSDLLTQNCDSLHSYDDEEKVVELHGAATDGVCEKCHELRNVDVETDTSPVCNVCG--SVLKPQVAFFEDTIRHRDAA
YNALSSCDLLLVVGTYCAVDPVLSFVRNAKRNGTILVEINPAESNGSQFMDVSIRYSANDAFKLIAENLY---------
>tr|A2DP91|A2DP91_TRIVA Transcriptional regulator, Sir2 family protein OS=Trichomonas vaginalis GN=TVAG_016210 PE=4 SV=1
-------------------------------NLANLIRNKGNICIITGAGISAH-VLPTFRSSKGLWDVVADKSL-DKFQFYSQPDVSWKLWASIRDLQK
QKFLYPSKAHRVIHYLMKY-GYIDTLLTQNIDSLHSFQGDSKIIELHGKVTEGECEKCNRKTPVDHKSGKCPKCPVCN--SNLRPTVAFFQDLIKARQKA
TKICQTTDLLILIGTHCVVDPVVTLVAEAFQSGATVVEINPDETRISDKCDMKFYEKADEALVAVGNILF---------
>tr|T0S2I2|T0S2I2_9STRA Uncharacterized protein OS=Saprolegnia diclina VS20 GN=SDRG_03389 PE=4 SV=1
------------------------------ERIAHLIATAKHLVVFTGAGVSTSTGVPDYRGENGIRKSSKKK--------QRSNAVIPDL--------H
--TLVPSPAHMALAELYRM-GRVKHVVTQNVDNLHRKSGIDALTELHGNATFGRCDTCEYVYEEAFPVFTQAACPSKS-NGYLQRYVIGFDAPMDDIDAA
IDHCEAADVALVLGTSLRVEPFCEMAGSFA---KHLVLVNLQPTKLDKRAGARVYDTCDRVLARVLQILKRD-------
>tr|W4G4T7|W4G4T7_9STRA Uncharacterized protein OS=Aphanomyces astaci GN=H257_10828 PE=4 SV=1
------------------------------KRLAQLIKTSKHLVAFTGAGISTSTGVPDYRGENGIRTKKSRL--------AKSPPVIPDF--------H
--SLVPSPTHMALYELYRL-GYLKHIVSQNVDNLHRKSGIVHLTEVHGNATFARCDTCEKVYKDNFPLSNSDACPSHG-NGRLKRYVIGFNEPMDDIDVA
IDHCEVADVALVLGTSLRVEPFCEMAGDFA---NHLIIVNLQKTRLDKRAGVRLFASCDVVMARVMQHLM-E-------
>tr|A0A024UA13|A0A024UA13_9STRA Uncharacterized protein OS=Aphanomyces invadans GN=H310_05543 PE=4 SV=1
------------------------------KRLAHLIKTSKHLVAFTGAGISTSTGVPDYRGENGIRKKSR-R--------TTVPPVIPDL--------H
--SLVPSPTHMALYELYRL-GYLKHIVSQNVDNLHRKSGIAHLTEVHGNATFARCDTCEKVYKDNFPLTNNDACPSHG-NGRLKRYVIGFNEPMDDIDIA
IDHCEIADTALVLGTSLRVEPFCEMAGDFA---KQLIIVNLQKTRLDKRAGVRLYASCDLVMSRVMEYLMAD-------
>tr|A0A0C3BD55|A0A0C3BD55_9HOMO Uncharacterized protein OS=Piloderma croceum F 1598 GN=PILCRDRAFT_818584 PE=4 SV=1
------------------------------NKVIKAIMKAKRIVVICGAGISVQAGIPDFRSPEGLFQTLSGKDLFDASVFNSEHT-TSLFCQMIAQLSN
SQAAMPTPFHKILRALDDR-GKLLRVYTQNIDAIESKSGLPRCIPLHGTLQTLHCQTCTHTFPLEDHLGTPPYCPECTAVGKLRPSVVLYNETHKDGEGV
RKDLSGADLLLVVGTSLRVPGTKRIVREFAKSMLKSVYLNLDFTRWEGVFDAWVQGNAQDFAEILGQEIEE--------
>tr|K5XU62|K5XU62_AGABU Uncharacterized protein OS=Agaricus bisporus var. burnettii (strain JB137-S8 / ATCC MYA-4627 / FGSC 10392) GN=AGABI1DRAFT_41488
------------------------------RKVIQAILKARRIVVVCGAGISVQAGIPDFRSPEGLFQTLSGKDLFDASVFNSEHT-TSLFCQMIAQLSR
SQDAEPTSFHRVLRALDDR-GKLLRVYTQNIDAIEQKTGLPRCIPLHGTLQSVHCQTCTHSFPLQEHLGQPPQCPECTSIGKLRPSVVLYNEAHKDGEGV
SKDLSGADLLLVVGTSLRVPGTKRIVREFSKDSIKAVYLNLDFTRWEGVFDVWLQGDAQTFARMLQEEIEK--------
>tr|A0A0C3B8P5|A0A0C3B8P5_9HOMO Uncharacterized protein OS=Serendipita vermifera MAFF 305830 GN=M408DRAFT_325981 PE=4 SV=1
------------------------------DRAARAVAKAKRIVVVSGAGVSVQAGIPDFRSPDGLFQQLSGKELFDASVFHSEST-ASIFYKMIARLAR
VEHAEPTPFHSMLKGLDDR-GQLLRCYTQNIDGIEEKAGLPRCVPLHGTLKSLHCITCGATASLSELAGSAPACQQCSEVGVMRPSIVLYNEDHREGERV
KRDLAPPDLLLVAGTSLRVPGTKRIVKEFSKSPIRTIYLNLDFARWESTFDMWVQGDIQEFVQRVQVAMKQ--------
>tr|V6M3U6|V6M3U6_9EUKA NAD-dependent histone deacetylase Sir2 OS=Spironucleus salmonicida GN=SS50377_11898 PE=4 SV=1
------------------------------EDSVQLIRDASSILILAGAGISVSAGIPDFRSPTGIYDQPTPTSIFDIAYFPKRPRP---FFHLSKSIFP
STEFQHTVTHAFFAYLQKT--KQTQILTQNIDDLEIQAGA-VANPVHGSFMSAKCVSCGRSFPTINAVDAVSFC-VCG--GVVKPGIVFFGENVNIPQQI
SQL--APDLLIVAGTSLRVGPVNQIPLMVK---CPKIFINREAPPAEYAFEQFLQGDCDDVVEVLLEQLGA--------
>tr|A0A0D0WN51|A0A0D0WN51_CRYGA Unplaced genomic scaffold supercont1.15, whole genome shotgun sequence OS=Cryptococcus gattii CA1873 GN=I314_05243 PE=4 SV=1
-----------------------------LRQVVARVRTANRIVVVSGAGVSTAAAIPDFRSASGLFSGHSIKDLFHVRCL-AHPTLLAKHITSLSSL--
STAAPPTPFHTYLSSLDNE-GRLLRCYTQNIDGLEVKTGLPRVIPLHGLLSTLHCTLCHTILPLPPHLPTSVPCPTCELSGTLRASVVLYGEEHPEGKSV
SRDLKGVDMLLVCGTSLSVPGVKRVVKEMAKQDVKTVFVNEEPPEWDGIFDIWVQGDVQKFVENYLQ------------
>tr|D2JWX0|D2JWX0_9TREE Putative Sir2 family histone deacetylase Hst4 OS=Filobasidiella depauperata PE=4 SV=1
-----------------------------LRQVILCLHKSKRIVIVSGAGVSTAAAIPDFRSVSGLFNEYSVKDLFHVRCL-AHHTLAAKHITYLSSL--
SLLAPPTPFHRYLSSLDQE-GRLSRCYTQNIDGLEKKAGLPKVIPLHGLLSTLHCTLCSTRFPLPPYLPSLIPCPTCQLSGFLRASVVLYGEEHSEGKAV
ARDLKSVDYLLVCGTSLSVPGVKRVVREMSKQEIKTVFVNEEPPEWEGVFDVWVQGDVQRFIG-YLD------------
>tr|A0A0J1B1L4|A0A0J1B1L4_9TREE DHS-like NAD/FAD-binding domain-containing protein OS=Trichosporon oleaginosus GN=CC85DRAFT_328993 PE=4 SV=1
-----------------------------LCTVVRRIRGAKRVVVVCGAGVSTAAQIPDFRSAHGLFARRNVKDLFHVKSL-TSPALLPDHLSTLSRL--
AGEAQPTAFHAFMRDIDRE-GRLLRVYTQNIDGLEERAGLVRCIPLHGLLSSLHCTQCAASVPSAAHA-APIPCPRCDEVGTLRASVVLYGEEHPQGSVM
ERDLRGADLLVVAGTSLSIPGVKRIVKEMAKPPVRVVYVNAEPPEWDGVFDVWVHGDVQDFAA-LVA------------
>tr|K1VQC2|K1VQC2_TRIAC Uncharacterized protein OS=Trichosporon asahii var. asahii (strain CBS 8904) GN=A1Q2_02891 PE=4 SV=1
-----------------------------LEDVVRRVRGARRIVAVAGAGVSTAAAIPDFRSSKGLFSGTGVKDLFHVKSL-TSPALLAKHLTDLCER--
ANRASPTAFHVLLASLDGD-GRLLRCYTQNIDGLEQRVGLPRCIPLHGLLSKLRCSLCSTFVPIDDHLPSTIPCPTCDLVGALRADVVLYGEEHPEGSVV
GRDLRGVDLLLVAGTTLAIPGVKRIVKEMAKPPIRTVFINNEPPEWDGIFDVWVQGDVQDFAA-LVE------------
>tr|M1JKD1|M1JKD1_ENCCN Sir2-like protein involved in telomeric silencing OS=Encephalitozoon cuniculi GN=ECU03_0460 PE=4 SV=1
----------------------------------IKMFAKRRVVVITGAGISVSSGIPDFRSKSGLFNDISGNDLFTYSLSM-SKELRKGYISKLKNMV-
-DKAQPSATHEFLSLYSDI-SRRFRIYTQNIDGLEEKAGLTRLVYLHGNMKSLGCLYCGYKIEFGDAAGEEIVCAGCVRVGVFHTTIIHYNQSHPFISKM
AEHDNTCDLFIVMGTSLKVFGVRRLVKYFCRTRGRRILVNLDRPSFGELFDFFWNGDCDEFCRVLKDGLG---------
>tr|I6ZSU9|I6ZSU9_ENCRO SIR2-like protein involved in telomeric silencing OS=Encephalitozoon romaleae (strain SJ-2008) GN=EROM_030350 PE=4 SV=1
----------------------------------IKMFSRRKVAIVVGAGISVSSGIPDFRSRSGIFNDISGSDLFTYSTSM-SKEMRKDYMSKLKDMI-
-DRAAPSPTHEFLSLYSDV-SKKFRMYTQNIDGLEEKAGLATVVYLHGNMKKLGCLYCGYKVDFGDTTGEEIVCSACIRVGVFHTTIIHYNQSHPFISKM
TQYDCDCDLFIVMGTSLKVFGVKKLVKYFCRTRGRRILVNLDKPSFGDLFDFFWNGDCDEFCKALNEELG---------
>tr|I6TI47|I6TI47_ENCHA Sirtuin-like protein OS=Encephalitozoon hellem (strain ATCC 50504) GN=EHEL_030370 PE=4 SV=1
----------------------------------IKMFSKRKVAVVVGAGISVSSGIPDFRSKSGIFSDISGSDLFTYSMSM-SKEMRKNYMSKLKGMV-
-DRAVPSPTHEFLSLYSDA-SRKFRMYTQNIDGLEEKAGLAKLVYLHGNMKKLSCLYCGYKIEFGDSAGEEIICPNCIKVGVFHTTIIHYNQSHPFISRT
AQNDSDCDLFIVMGTSLKVFGVKKLVKYFCRTRGRRILVNLDKPSFRELFDFFWNGDCDEFCKALGEELG---------
>tr|S3C8L2|S3C8L2_OPHP1 Sir2 family protein OS=Ophiostoma piceae (strain UAMH 11346) GN=F503_06953 PE=4 SV=1
------------------------------GYLLRALRTKKKIVVIAGAGISVSAGIPDFRSSTGLFTTLSGKHLFDASVYKHDSST-SSFHTMVRELAH
TQTAKPTAFHHMLASLAQE-GRLMRLYSQNVDCIDTNIEPPTTIQLHGGLAKMVCSKCGQLEDFDGSLFEPPPCVPCTTIGRLRPRIVLYNEYPDEIGNV
ADLRRGADAVIVVGTSLKIPGVRRLVKELCLRDGFTAWINVDAEPAEDCWDLVVRGGSDDVA-----------------
>tr|W3XNW3|W3XNW3_9PEZI Uncharacterized protein OS=Pestalotiopsis fici W106-1 GN=PFICI_01483 PE=4 SV=1
------------------------------NRLTSTLRQKKKIVIIAGAGISVSAGIPDFRSSKGLFKTLSGQQLFDASVYKHNDST-ETFHAMVRALSD
TKQAKPSAFHHMIASIAEE-GRLLRLYTQNVDGIDTSMPSPKTVQLHGGLDKMSCSKCSELYDFDGSVFEPPPCPGCTEVGRLRPRMVLYNEHPDQITKV
ADTKTRPDAVVVVGTSMKIPGVRKLVQDLCYRDGFTAWINLDQEPVDDCWDLVVRGKCDDVA-----------------
>tr|A0A0C4DT61|A0A0C4DT61_MAGP6 Sir2 family histone deacetylase Hst4 OS=Magnaporthiopsis poae (strain ATCC 64411 / 73-15) GN=MAPG_03118 PE=4 SV=1
------------------------------TRLMTVLRKKKRIVVIAGAGISVSAGIPDFRSSTGLFTTLSGKHLFDASVYKDDSST-SSFHTMVKELAA
TERAQPTPFHHMLASMAQE-GRLMRLYTQNIDCLDTEMEPPKTIQLHGGLAHMVCTKCGRLQDFDPKCFEPPPCSICEAVGRLRPRIVLYNEDPDAIGQV
ADLRRLPDAVIVVGTTLKIPGVRRLVREMCKRDGFTAWINVDGEPAEDCWDLVVKARCDDVA-----------------
>tr|A0A0C2ID33|A0A0C2ID33_9PEZI Sir2 family histone deacetylase OS=Sporothrix brasiliensis 5110 GN=SPBR_04718 PE=4 SV=1
------------------------------GYLIRALRKKKKIVVIAGAGISVSAGIPDFRSSTGLFTTLSGKHLFDASVYKHDSST-SSFHSMVRELAH
TDAAVPTPFHHMLASIAHE-GRLMRLYSQNVDCIDTKMPPPTTVQLHGGLAKMVCSKCGQLEDFDGSLFEAPACSQCTVIGRLRPRIVLYNEYPDEIGMV
ADLRRGADAVIVVGTSLKIPGVRRLVKELCHRDGFTAWINVDPEPAEDCWDLIVRGSSDDVA-----------------
>tr|A0A067T782|A0A067T782_9AGAR Uncharacterized protein OS=Galerina marginata CBS 339.88 GN=GALMADRAFT_244772 PE=4 SV=1
------------------------------SRVVHAIMKAKRIVVICGAGISVQAGIPDFRSSDGLFQTINPKELFDVSVFNSEQK-TSLFCQM-IAQLS
SQAAEPTSFHHVLRALDDR-GRLLRVYTQNIDAIEQKSGLPRCIPLHGTLQSMHCQICNHSFPLPPYLGQPPSCPECTAIGKLRPSVVLYNEAHKDGEVV
QRDLGGADLLLVVGTSLRVPGTKRMVREFAKRPPKAIYLNLDFTRWEGVFDAWIQGDAQEFAEVLRAEIVKEA------
>tr|A0A067Q152|A0A067Q152_9HOMO Uncharacterized protein OS=Jaapia argillacea MUCL 33604 GN=JAAARDRAFT_194385 PE=4 SV=1
------------------------------TKVLKTILKAKRIAVVCGAGISVQAGIPDFRSSDGLFQTLNPRDLFDASVFNSEHT-TSLFCQM-ISRLS
SQAASPTPFHKLLRTLDDR-GRLLRVYTQNIDALESKSGLPRCIPLHGTLQEMHCQSCNHSFPLADHIGVPPPCPECTAVGKLRPSVVLYNEMHKDGEVV
RKDLAGADVLVVVGTSLRVPGTKRIVREFSKRPLKTIYLNLDFTRWEGVFDVWIKGDAQMFANMLVAELEKED------
>tr|A0A0C3CA44|A0A0C3CA44_HEBCY Uncharacterized protein OS=Hebeloma cylindrosporum h7 GN=M413DRAFT_162127 PE=4 SV=1
------------------------------ARTVRAIMKAKRIVVICGAGISVQAGIPDFRSSEGLFQSINPKELFDVSVFNSEQK-TSLFCQM-IAQLS
SQAAQPTAFHHLLRALDDR-GKLLRVYTQNIDAIEQKSGLPRCIPLHGTLQSMHCQTCNHSFPLLPHHGQPPPCPECTSIGKLRPSVVLYNEAHNDGEVV
RKDLSGADLLLVVGTSLRVPGTKRMVREFAKRLPKAVYLNLDFTRWEGVFDAWVQGDAQEFAAVLRAEIEKEA------
>tr|A0A0D2Q3N9|A0A0D2Q3N9_9AGAR Uncharacterized protein OS=Hypholoma sublateritium FD-334 SS-4 GN=HYPSUDRAFT_36454 PE=4 SV=1
------------------------------TKAVQAIMKAKRIVVICGAGISVQAGIPDFRSAEGLFQTINPKELFDVSVFNSEQR-TSLFCQM-IAQLS
SQTAEPTSFHHVLRALDDR-GRLLRVYTQNIDAIEQKSGLPRCIPLHGTLQAMHCQICNHSFPLHDYMGQPPQCPECTSIGKLRPSVVLYNETHKDGNVV
QKDLSGADLLLVVGTSLKVPGTKRMVREFAKRTPRAFYLNLDFTRWEGVFDAWIQGDAQHFAEILQAEIEKET------
>tr|A0A0N5CYQ8|A0A0N5CYQ8_THECL Uncharacterized protein OS=Thelazia callipaeda PE=4 SV=1
---------------------------------ADILKKSKCTIVYTGAGISTAASIPDYRGPNGVWTLAE-KGIVSLK--CADPI--------------
--QSEPTASHMILKEMCRK-GLIRHVLSQNCDGLHLRSGLKMLSEIHGNMHIEVCQHCEPQYIRPYDVTTGRMCEVCN--NELADTIVHFGEAPWNWNGI
IPLISKCDVILCIGTSLTVLKEYSFLWPKSKSNTQIAIVNLQWTPKDRVSCLKINAKCDTVMKKLANIFE---------
>tr|E1G527|E1G527_LOALO Transcriptional regulator OS=Loa loa GN=LOAG_08259 PE=4 SV=2
---------------------------------AGLLKKSKCTVVYTGAGISTAASIPDYRGPNGVWTLAE-KGIVSLK--CANPV--------------
--ESGPTASHMILKEMCRS-GLVRHILSQNCDGLHLRSGLKMLSEIHGNMHIEVCQHCEPQYIRPFDVTTGRMCLVCN--NELADTIVHFGEAPWNWNGI
ISLIDRCDLILCIGTSLAVLKEYHFLWPKPRCGTQIAIINLQWTPKDRLSCLKINAKCDIVMEKLAGLLG---------
>tr|A0A0L0D5N8|A0A0L0D5N8_THETB SIR2 family Histone deacetylase OS=Thecamonas trahens ATCC 50062 GN=AMSG_03889 PE=4 SV=1
----------------------------------QRLGRTPRIVVLAGAGLSVSAGIPAYRTSDGVYSTAAGRSAFQASAVASDPVS---FYAKMAELFG
TGEITPTSAHYFVAELAAR-GELAAILTQNVDMLEVAAGIDKIVEAHGTMRRFRCLDCSSEAVWPRVLGDVPVCAACG--STLRPCVVFFGEGLPSFTEA
RNVMEHADLLIVIGTSLMVYPFGALVNEVSL-LTPRVLINREPVGPDNYRDVALLGDADDGAHALAA------------
>tr|A0A0N0NKC3|A0A0N0NKC3_9EURO NAD-dependent protein deacetylase hst1 OS=Phialophora attae GN=AB675_3078 PE=4 SV=1
------------------------------DDAVRLLKESKNIGILCGAGISTAVGIPDFRSKDGLYNSTDPQQLFYRETFEDDPKAFWTDVFPIIQVLR
AIAAIPSKVHSFFDLLQSK-GKLNTIFTQNIDALELAADVDKIIACHGSWDTATCLSCDGKIHANDPVHKLPLC-ECGRRGLLKPDITFFGESVSSYQRL
DAVKDDLDLLIIIGTSLAAAPVSQLPLEIPP-DVPQIWVSNKTKSLVLQVDIELIGDADSIITELCAR-----------
>tr|W2RL74|W2RL74_9EURO Uncharacterized protein OS=Cyphellophora europaea CBS 101466 GN=HMPREF1541_08752 PE=4 SV=1
------------------------------QDAVDLLKESEDIVILSGAGISTSVGIPDFRSQQGLYNLSDPQQLFYRDMFEQYPKEFWRDVRPIRQLLN
LINAVPSAVHSFLELLQTK-DKLLTNFTQNIDALELDAGVEKIVACHGTWETATCLSCAGKVAAQSPVGKLPLC-VCGKPGLLKPDITFFGESVENYYTL
DAIRDEVDLLIIVGTSLAAQPVSELPLSLPR-DVPQIWISNERTNKVLQVDIELIGDADSIVRELCAR-----------
>tr|A0A061B1X6|A0A061B1X6_RHOTO RHTO0S08e08196g1_1 OS=Rhodosporidium toruloides GN=RHTO0S_08e08196g PE=4 SV=1
--------------------------------LALAVAKGKRTVLLVGAGISTNAGIPDFRSSTGLYSSGPPTTLKGPDLFSASPDEHLRFIAHFKRSLD
DETRPATATHDFMRLLKKR-GKLQRVYTQNIDGLEGVGGLGDYVQLHGSVHAVRCTSCAFVRRWTEEDVHVGACPECEGRAYLRPSIVLYSEPPPLSSLS
LSDLPGPDVMLVMGTSLRIPGFKKLVKEFGSRGGVRVLVNREEIGGKGVFDYEIIADTDSFVTRLIEGWKR--------
>tr|A0A0D6EKR1|A0A0D6EKR1_SPOSA SPOSA6832_02216-mRNA-1:cds (Fragment) OS=Sporidiobolus salmonicolor GN=SPOSA6832_02216 PE=4 SV=1
--------------------------------ITLAVAKSKKAVVLVGAGISTNAGIPDFRSKTGLYPPASGSTLKGPSLFSSSSHQHLHFLSTFKSTLD
ST--PPTATHGFLNILKKR-GQLRRVYTQNIDGLEEK-GLGDFVQLHGSIHRVRCTACDYVAVWTDKPAQVAECPRCEDRSFLRPAITLYDEASPA-SVS
LSDLGGPDLMLVMGTSLKIPGFKKIAKEFKAKGGVRVLVNREEIKGKDVFDYHILADSDTFVNRVVGDWKR--------
>tr|A0A0P9F9H0|A0A0P9F9H0_RHOGW Uncharacterized protein OS=Rhodotorula graminis (strain WP1) GN=RHOBADRAFT_47122 PE=4 SV=1
--------------------------------LTLAVARSKRAVLLVGAGISTSAGIPDFRSQTGLYSTPPPATLKGPALFSASPDEHLRFIAAFKRSLD
STPGPATPTHDFMRLLKKR-NKLLRVYTQNIDGLEGVGGLGDYVQLHGAVHAVRCTGCDFVRTWTDEDGSVGVCPQCEERAFLRPSITLYNEAPPSAALS
LSDLPGPDVMLVLGTSLKIPGFKKLVKEFKSRGGVRVLVNREEVGSRDVFDYQVLGDTDAFVTRLVGDWKR--------
>tr|U5H029|U5H029_USTV1 Uncharacterized protein OS=Microbotryum violaceum (strain p1A1 Lamole) GN=MVLG_00769 PE=4 SV=1
--------------------------------MTAAIAKAKRVVVAVGAGISTSAGVPDFRTKSGLYARADSNLLKGPAMFTSAVSAHWQFMTRLKRSVD
HAERGVTKTHAFFDTLHRR-GQLGRVYTQNIDGFELTSQLGDVVQLHGSLGRVKCSSCAWVGEWDERHSMSVDCPACVSRSFVRPSIVLYDERSPA-EQI
TCDLRKPDLLIVMGTTLKIPGFKRLVVDMRKNGGLAIFVNREKNAAKKVFDYQVIGSTDDFVDRLLKRWKQ--------
>tr|W0SG77|W0SG77_9RHOO Uncharacterized protein OS=Sulfuritalea hydrogenivorans sk43H GN=SUTH_02147 PE=4 SV=1
----------------------------------DRARPAGATLVLTGAGVSTASGIPDYTA--GHWLAPVPASRYSYGAFLADAESRSLYWDACREVA-
-ARAKPNNGHLALAGLEAS-GYILATITQNVDGLHQAAGSRQVGELHGTIFSVRCLACDHEAEWPADLHASPCCEMCG--GLLKPAVIAFGESIATWHDA
TEKAAQCGAILVVGSQLAVSSASALLASARARGVPCVFLTLGSLAVPFPGDTVIDGPAELVLPALARLLE---------
>tr|A0A099KHU3|A0A099KHU3_COLPS Urea transporter OS=Colwellia psychrerythraea GN=ND2E_3743 PE=4 SV=1
----------------------------------NRLR-AKHCVAITGSGIR-KGALPDYPS--GQWLDPVPITSYTLAEFKASKRCRYLYWKASYQQA-
-LTMNKNNIDKQLDSL-LN-YYLSGLFTETVDSLLTN-EQHPIYECYGSIKNLYCLDCAQQQAWPPPLQRDLHCQHCS--GLLKPQILAADENIECYQAL
QTNMANCGSLLVIGVPAVTPVVSMIIENANANKIPIIFIGTLPSTYLEAKDIQLTGDIANWLTYINWFTN---------
>tr|Q480E0|Q480E0_COLP3 Putative membrane protein OS=Colwellia psychrerythraea (strain 34H / ATCC BAA-681) GN=CPS_2874 PE=4 SV=1
----------------------------------NRLR-AKQCVAITGSGIR-KGTLPDYPS--GQWLDPVPITSYTLAEFKASKRCRYLYWKASYQQA-
-LTINKNNIDEQLDYL-LN-HYLSGLFTETVDSLFNT-EQHPVYECYGSIKRLYCLDCAKQQAWPPPLQRDLHCQHCS--GLLKPQILAADENIECYQAL
QKNMMECGCLLVIGVPTITPVVSMIIENANANKIPIIFIGTIPFGYFEEKDVQLTGDIAHWLAEINGFIN---------
>tr|A0A087SJV4|A0A087SJV4_AUXPR 3-isopropylmalate dehydratase OS=Auxenochlorella protothecoides GN=F751_3646 PE=4 SV=1
------------------------------EKLIQLVSEARSIIAFTGAGISTSTGIPDFRGPNGVWTAQK---LGTA-----LPKATVEF---------
-ANAAPSLTHQALLALHGT-GKLKYLVSQNVDGLHRRSGFPALAELHGNCFLERCSTCGATFTRDFEVETGRFCEVCR--GPLTDTVLDWDDALPELKEA
ELRAKHADLAICLGTSLQIRPACNLPLRTVRQAGKLVIVNLQRTQHDKKGGLVIHARTDDVMRGLMAGLH---------
>tr|A0A0A9YF61|A0A0A9YF61_LYGHE NAD-dependent deacetylase HST1 OS=Lygus hesperus GN=HST1 PE=4 SV=1
-----------------------------LQDVVHCVQNSKQILIVSGAGISVAAGIPDFRSIYGIYNTFDVDNLFNLETFLQRPQPFYTFL---YTMLL
WKDIQPTRMHQFFHQLQRN-NQLLRIYTQNVDMLEKKVGIDKLLFCHGSAHTYTCMTCRRKVSWRILKEILPCCYLCT--GLLKPDIIFYGESLSIFTTI
QHDAAICDLVLVVGTSLTVSPVNTFLQLIPT-HVPIINISREPILFVYMFSYQCIGDADTVAQALLKGITD--------
>tr|R7UG42|R7UG42_CAPTE Uncharacterized protein OS=Capitella teleta GN=CAPTEDRAFT_228445 PE=4 SV=1
--------------------------------LAQAIRNAKSVVLYTGAGISTAASIPDYRGPSGVWTLLQ-QGI--------QPKV---------QDLS
--VAEPTYTHMAIKKLHQM-GVVKHVVSQNCDGLHLRSGLPALSEIHGDMFIEVCHSCNPEYLRLFDVQTGRLCSDCG--QELRDSIVHFGERPYNWEEA
AQAADQADLILCIGTSLKVYPCLWSPHKPPTQKPELYIINLQWTPKDDGAILKINGKCDVVLKQLLLHLG---------
>tr|D2VRI8|D2VRI8_NAEGR Silent information regulator family protein OS=Naegleria gruberi GN=NAEGRDRAFT_71599 PE=4 SV=1
------------------------------SQLAQVLKNCKHCTVYTGAGISTSAKIPDYRGPKGVWTLKSSNEIAK---------------------ID
IEQALPTFTHYAIKHLIK-LGFVKYVVSTNVDGLHRRSGLDELSELHGNCYREVCADCGKEYLRGFDVLTGRFC-ECG--GKLKDTIIHFSESLPELDNA
IDHSKKSDLSLVLGTSMMVNPAAQLPKMALKKGSIMCIVNLQKTPCDNLSALRVFSKTDEFMRLVMEELGELDN-----
>tr|A0A061D3Y4|A0A061D3Y4_BABBI Transcriptional regulator, Sir2 family domain containing protein, putative OS=Babesia bigemina GN=BBBOND_0205940 PE=4 SV=1
------------------------------KKLSTLLSDSKYTLLHTGAGISTAAGIPDFRGPSGVWTVMKRRKMTDGDCTAKNTGDAVEYGHKKLEPVE
FSQAMPSEAHLAILALLRA-GHVQAVITQNIDGLHAISGMSECSELHGNVFIERCISCGRRFLRPYVISTGNHCGICHFCGVLTDVVLWFDRYEDHFKRA
ISYAEEADLHLALGSSLHVEPACHYASSERKEDAPLVIVNYQKTRLHGEADVVLHCDVNKICTRLLKSL----------
>tr|A7AWG1|A7AWG1_BABBO Transcriptional regulator, Sir2 family domain containing protein OS=Babesia bovis GN=BBOV_I003070 PE=4 SV=1
------------------------------KQTVELLTRAKNVVLHSGAGMSTAAGIPDFRGPSGVWTVMKKRKMTDGDCTVKDTSNCVEFGTTKLEPVE
FSHALPSEAHLATLALLRA-GYIRTVITQNIDGLHAISGMSECIELHGNVFIERCIFCARRYLRPYVISTGSHCGLCNFYGILTDVVLWFDRYEDHFKRA
ISHAEEADFHLTLGSSLHVEPACCYASSERKENAPLVIVNYQKTRLDPEADVVLHCDVNQICKKLLKTF----------
>tr|A0A0F4ZEX1|A0A0F4ZEX1_9PEZI Uncharacterized protein OS=Thielaviopsis punctulata GN=TD95_002336 PE=4 SV=1
------------------------------DMLLNALRKKKKIVVIAGAGISVSAGIPDFRSGHGLFKTLSGKQLFDASVYKDNNM-TESFHAMVRQLSA
TKAAEPTPFHHMLASLAEE-GRLLRLYTQNIDCIDTSGPWPTTIQLHGSVQHMVCSKCNFLSELQGDLFVPPSCARCHEVGKLRPRIVLYNESPDE--EA
IDLRARPDAVLVVGTTMKIPGLKRLVKELRRRDGFTAWINLDPEPQEDCWDLVVKARCDDVA-----------------
>tr|A0A0C3HFJ2|A0A0C3HFJ2_9PEZI Uncharacterized protein (Fragment) OS=Oidiodendron maius Zn GN=OIDMADRAFT_77062 PE=4 SV=1
------------------------------KKLVDTLRRKRKIVVVAGAGISVSAGIPDFRSSTGLFNTLSGKHLFDASVYRSDSS-TSSFHDMVRELSH
TQEAKPTPFHHMLATIAEE-GRLMRLYTQNVDGIDVAAPWPKTVQLHGGLSKMVCTKCGHLSDFNGALFEPPSCQECEVIGRLRPRMVLYNEFPDE--EA
IDLKSRPDAVIVVGTSLKVPGIRRLVKELRRRGGCTAWINYDPEPVDDCWDLVVRGECDEVA-----------------
>tr|D2VDV6|D2VDV6_NAEGR Silent information regulator family protein OS=Naegleria gruberi GN=NAEGRDRAFT_67056 PE=4 SV=1
-----------------------------------YVKDSKHLVIYTGAGISTESGIIDYRGPKGIWTMLKQG---------KEPVKSVPF---------
--IKFPTKCHMAISELYKQ-KKLKYLTSQNVDGLHLESGIDCMSEIHGNTNIEICKECEIEYVRDYSVTTGRFCNKCG--KELFDTIVNFNDPLDWFERA
LEHSKLADVAIVLGTSLKVLPICDLPQLCKFHKGKLIIVNLQTTPKDIYADVKINMKTDEFMERLMNGLGY--------
>tr|A0A0F7SVK2|A0A0F7SVK2_PHARH Sirtuin 5 and related class III sirtuins (SIR2 family) OS=Phaffia rhodozyma PE=4 SV=1
-----------------------------------SVAKSKKIVVVSGAGISCSCGIPDFRSQDGLYNLYTGKDLFSSSLFRSSTSLFYSFIAELKLSI-
-DAVEPSKTHLFVKKLDEK-GKLMRSYTQNIDGLERRAGLTKNVQLHGDIHQVRCMVCQSSYDFTPEYGDAPECPACEETGVLRPSIVLYDENHPNGDQT
HDLSKTPDLLLVLGTSLKVHGLKRLVKELRPHGGRVVFVNKTEPQGKGVFDYWVKGDCDAFVSKVEEEW----------
>tr|A0A0L0DFJ6|A0A0L0DFJ6_THETB Uncharacterized protein OS=Thecamonas trahens ATCC 50062 GN=AMSG_12024 PE=4 SV=1
----------------------------------GLIAQARKGYFFTGAGLSTSAGISDYRGPNGVWTRRA-QGR-------SAPRG---------V--R
ITQATPTYAHMAVAALVET-GEMRGVVSQNVDGLHRRSGVADIAELHGNCYLEVCWKCEMEHDVSERINRVPKCGRCG--AVLKDSIIHFGENLPDLEKA
FAWGRKADLCVVLGSSLRVTPAADVPAETAGRGGDLVIVNLQKTPLDDEASLIIRGRIDDVMTRVMAELGR--------
>tr|D7G3Z0|D7G3Z0_ECTSI Chromatin regulatory protein sir2, putative OS=Ectocarpus siliculosus GN=Esi_0054_0036 PE=4 SV=1
---------------------------------ASLLRAAPIAVAHTGAGLSTAAGIPDFRGKDGVWTLENQG----------QPLP---DYEK-----C
WDNAMPTLGHMALVGLVNE-GFVHAVISQNVDGLHLRSGIEKLCELHGNLFMEICSGCGKEFRRTADVGTGRRCRECGE-GLV-DALLDWEDELRDYEQA
VDLSERGGVSLCLGTSLQISPSKDLPAKA----DKMVIVNLQKTCKDARAAIVIRAKIDAVMRCVMQEL----------
>tr|E0VRL7|E0VRL7_PEDHC Chromatin regulatory protein sir2, putative OS=Pediculus humanus subsp. corporis GN=Phum_PHUM399890 PE=4 SV=1
---------------------------------AKWINEANHVVIHTGAGISTSAGIPDFRGPRGVWTLQA---------KGEKPDLSKDF---------
-NEAIPTVTHMAIMKLVEK-QKVKYVVSQNIDGLHLRSNLKYLSELHGNMFTEQCNSCNRQFVRSSPVPTNKNCPPCR--GRLHDTILDWEHNLPELGMA
DYHSCLADLSICLGTTMQIVPSGNLPLYTKRHGGKLVIVNLQPTKHDRKANLLIHAYVDEVMTMLMKHLN---------
>tr|S8BM03|S8BM03_DACHA Uncharacterized protein OS=Dactylellina haptotyla (strain CBS 200.50) GN=H072_10182 PE=4 SV=1
------------------------------QEIADSICRSGQVLMVTGAGISTNSGIPDFRSANGLYNLYKGKDLFDAISF-TNPIILYSFLAELRQTVK
-TIKDSTPTHKFIKTLSET-GRLLRCYTQNIDGLEALDGLCEVVQLHGDLEMLRCTQCAKLHDYDEEKGEAPECPDCTRVGTLRPNIVLYDEMHPQGDHY
DATRMTPDLLLIFGTSLKVIGLKRIVKAFKSRGGKVVYINATPASWGDIIDFHIKMDCDAWIKDLK-------------
>tr|A0A0G4N541|A0A0G4N541_9PEZI Uncharacterized protein OS=Verticillium longisporum GN=BN1723_005151 PE=4 SV=1
--------------------------------------RSPTTVILSGAGLSVSSGLADYRGAKGTYRVYRP---IYYHEFLASHEARKRYWA--RSFLG
WPRARPNAGHRAIADLGGGLGLVSAVITQNVDSFHPQAHPMPTLELHGYLRNTVCVTCHSEFPRDAEVFRYPACPSCLAAGILKPAVVMFGESIDEVKAA
EAAVDGAGRLLVLGTSLATFSAWRIAKRALDRGMPIAVVNVGGVRGEEQVDWRVELSTDKVLPAVVETLRRNN------
>tr|W9YGM9|W9YGM9_9EURO Uncharacterized protein OS=Capronia coronata CBS 617.96 GN=A1O1_05331 PE=4 SV=1
--------------------------------------STGKTVLLTGAGISVASGLADYRGEKGTYTQFRP---IYFHEFVASHEARKRYWA--RSFLG
WRRAAPNATHYAIRDLGR------SVITQNVDSFHHMAHPLPTIELHGFLRSLICLSCRRLMDREAELFRYPACPHCLKVGILKPNVIMFGESIAAVKAA
EAAVDAASKILVVGSSLATYSAWRLVKHAHERGMGIGILNMGGVRNEETVAWRASLPAEEILPGVVDYIRSQR------
>tr|H6C7H9|H6C7H9_EXODN NAD-dependent deacetylase sirtuin 4 OS=Exophiala dermatitidis (strain ATCC 34100 / CBS 525.76 / NIH/UT8656) GN=HMPREF1120_07660
--------------------------------------GGGKTVLLTGAGISVASGLADYRGSKGTYTQYRP---IYFHEFVASHEARKRYWA--RSFLG
WRRASPNAAHYAVRDLGR------TVITQNVDSFHPIAHPLPTIELHGFLRSLVCLSCKRLIDREAELFRYPACPHCLKVGILKPNVIMFGESIASVKAA
EAAIDAANKVLVVGSSLATYSAWRLVKRAHERGMGIGVLNLGGVRKEEAGDWRASLPAEEILPSVVEYIRSQR------
>tr|W9XDG8|W9XDG8_9EURO Uncharacterized protein OS=Capronia epimyces CBS 606.96 GN=A1O3_09429 PE=4 SV=1
--------------------------------------NTSKTVLLTGAGISVASGLADYRGEKGTYTQYRP---IYFHEFVASHEARKRYWA--RSFLG
WRHASPNATHYAIRDLGR------SVITQNVDSFHPLAHPLPTIELHGFLRSLVCLSCQRLMDREADLFRYPACPHCLKVGILKPNVIMFGESISAIKAA
EAAIDAAGKILVLGSSLATYSAWRLVKRAHDRGMGIGVLNLGGVRKEEVSQARASLPTEEILPGVVDYICNQR------
>tr|G4TMZ1|G4TMZ1_PIRID Related to HST1-silencing protein OS=Piriformospora indica (strain DSM 11827) GN=PIIN_06604 PE=4 SV=1
----------------------------TLSDAVKLIWRAQKIMVLTGAGISVSCGVPDFRSPDGIYAQDDPQEMFSLAEFVRRPAMFYSFIGQLW----
PEDIEPSLAHEFIRHLEIK-G-------KNIDSLETVAGVEAVFACHGSFATASCMDCGKKVPGSDAIGRIPRCQPCVDQKTIRPKAKAVGDNAPLMDLL
FSDREEVDLLLIMGTSLKVKPVSEILGHIP-HSIPQILINKTPIEH-ANPDIVLLGDCDDIVARLCHELGYIL------
>tr|R0M3Q4|R0M3Q4_NOSB1 NAD-dependent deacetylase hst4 OS=Nosema bombycis (strain CQ1 / CVCC 102059) GN=HST4 PE=4 SV=1
--------------------------------------YKKKVVIITGAGISVASGIPDFRSKSGIFAEFNGSDLFTYKFGI-NKETRRIYLKKLKKLV-
-EECKPSYTHLFFKYFVER-SRKFRVYTQNIDGLEIKGGLTELVHLHGDLKFLKCINCGIKEEFKEEFGLEIQCKSCKSPTYLHTNIIHYYQDHPLISNR
IQNDTGCNLLIVVGTRLDVFGVENMVKYFTNKKITSIFINPEHPKKKNYFEFYYPGKSDEFFENLKEEIE---------
>tr|T0L6G6|T0L6G6_9MICR Sir2-like protein involved in telomeric silencing OS=Nosema apis BRL 01 GN=NAPIS_ORF02337 PE=4 SV=1
--------------------------------------INKNVVIITGAGISVKAGIPDFRSKTGIFSDFKGEDLFTYKFGL-NDSTRHIYINNLKKLI-
-DNAKPTFTHNFFKWYQNK-CNKLRVYTQNIDGLEEKGGFDSLVYLHGNLKYLKCIRCGSLEEFNDVKDNFGNCKKCEKQTFLHTTIVHYYQDHPFISKC
IRDDSCADLCIVVGTSLNVFGVRNMIKYFYKMKCECFFVNIEDCRNDKYFKYLFKGSSDEFFSKIKEYSN---------
>tr|C4VA59|C4VA59_NOSCE Putative uncharacterized protein OS=Nosema ceranae (strain BRL01) GN=NCER_101498 PE=4 SV=1
--------------------------------------SQKKVVIIAGAGISVSSGIPDFRSKTGLFQDYKGEELFSYKFGI-ESRTRKIYLENLKRLI-
-NNSNPSYTHKFFKWYAQ--VTSLRVYTQNIDSLEEKGGLDNLVYLHGNLKYLRCLYCGSQSEFNNPT-NSPKCTICAEPKYLHTNIIHYHQDHPLISKC
IRKDSNLDLLIVVGTSLNVFGVKNMVKYFSKFCKNRIFVSLSNCSSSKYFTHFYKGTSDDFFRHVKKSVE---------
>tr|A0A0L1I2D5|A0A0L1I2D5_9PLEO Nad-dependent histone deacetylase sir2 OS=Stemphylium lycopersici GN=TW65_09346 PE=4 SV=1
------------------------------QRLLSVLRKKRKIVVIAGAGISVSAGIPDFRSATGLFKTLSGKDLFDASVY-QDDTLTSIFHDMVRKISQ
TKSAKPTAFHHLLATLAQE-GRLLRLYTQNIDSIDTSLGWPKTVQLHGGLDYMVCSKCQTMTPFDAEQFNPPPCLSCLEIGRLRPRMVLYNEYPDDISCA
YDMRKIPDAVIVVGTTLKVPGVRRIARELCNRNGVTIWINNDHEPVVDKWDLVVKGPCDEVA-----------------
>tr|D4B3Y5|D4B3Y5_ARTBC Uncharacterized protein OS=Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) GN=ARB_03174 PE=4 SV=1
------------------------------KLLLRTLREHRKIVVVAGAGISVSAGIPDFRSSHGLFSTLSGKQLFDASVY-QDESMISSFHDMVRTLSK
SASAKPTAFHHLLARLAHE-GRLLRLYTQNVDGIEASLGWPTTIQLHGGLHTMVCQKCSKASSFEADLFDPPLCAECEKIGKLRPRMVLYNEYPDEISVV
ADLRARPDALVVVGTSLKIPGVRRIVKEMCRRNGTTVWINHDPLPSEDCWDLAIKGDCDKVA-----------------
>tr|S8BMQ3|S8BMQ3_DACHA Uncharacterized protein OS=Dactylellina haptotyla (strain CBS 200.50) GN=H072_5394 PE=4 SV=1
----------------------------------DILNKKKKIIVIAGAGISVCAGIPDFRSSNGLFASYSGKQLFDASVYKDDK-STSDFHDMVRNLYS
MTEAQPTSFHHLLASLATS-GRLLRLYTQNVDCIETSLAPPKTIQLHGGLDKMNCSKCRVIKEFIPDIFTPPDCPDCVDIGKLRPRMVLYNEHPDQIGST
ADLRARPDCLIVVGTSLKIPGVQRLVRELCARGGKTVWINRDEPPATGLFDLVLKGDCETL------------------
>tr|U4LGV0|U4LGV0_PYROM Similar to NAD-dependent protein deacetylase hst4 acc. no. Q5BE04 OS=Pyronema omphalodes (strain CBS 100304) GN=PCON_10033 PE=4
----------------------------------KLLRKKKKIVVIAGAGISVNAGIPDFRGSDGLFAT-SGKDLFDASVYKDNF-LTASFHDMVRDLHG
LSRAQPTQFHHLLATLATE-GRLLRLYSQNVDCIETRLEPPRTIQVHGGLEKMNCQKCGWVGPLEPGLFEPPDCPECKEIGKLRPRIVLYNEFPDAIGSS
ADIKARPDAVIVVGTSLKVPGVKRIVSEMCKRGGLCVWVNKNDPPPAYAFDLVIRGDCEEL------------------
>tr|W7IGN9|W7IGN9_9PEZI Uncharacterized protein OS=Drechslerella stenobrocha 248 GN=DRE_02139 PE=4 SV=1
----------------------------------DILNRKKKIIVIAGAGISVRAGIPDFRSSNGLFASYSGKQLFDASVYKDDK-STSDFHGMVRNLHA
MNDAQPTAFHHLLASLAAS-GRLLRLYTQNVDCIETSLPPPKSVQLHGGLDKMTCSKCRVIKDFKPDIFKPPDCLDCLDVGKLRPRIVLYNEHPDEIGST
ADLKARPDCLIVVGTSLKIPGVQRLVRELCARGGKTVWINCDEPPATGLFDLIMKGDCETL------------------
>tr|I1F9M9|I1F9M9_AMPQE Uncharacterized protein OS=Amphimedon queenslandica PE=4 SV=1
--------------------------------IADWVRGSKHTILFTGAGISTSAGIPDFRSGPGVWEVR-AQGT-------SRPNT---------KITP
ILQASPTPTHMAIVKLHES-GLCKFTVSQNVDGLHRRSGLNQLSEMHGNTNMETCKKCGRQYLRDFQHTTSRLCDACK--GQLKDSIINFGENLPELTKA
FNHAQKADVCIVLGSSLRVRPACQVPEVVAGNKGKVVICNLQKIPQPSNNVLPVYSMCDTFMKKLMHELQ---------
>tr|M2M067|M2M067_BAUCO Uncharacterized protein OS=Baudoinia compniacensis (strain UAMH 10762) GN=BAUCODRAFT_28731 PE=4 SV=1
------------------------------DRVLNVLHKRQKIVVIAGAGMSKSAGIPDFRSKNGLFSSLSGQHLFDASVYKDDAS-TKQFHQMMSRLV-
-KDAKPTPFHHMLATIAKE-ERLLRLYSQNVDCLETNMGKPRTLQLHGGLDKMVCTKCHEIYDLDPELFDAPLCSECEKIGRLRPRMVLYHEDPDNIGTA
ADLKRKPDAVLVVGTTLKVKGLQRIVMEMCRKGGLAIWINPELPPTTDLFDIIVQGTCDEVA-----------------
>tr|B8CFK0|B8CFK0_THAPS Histone deacetylase HDAC silent information regulator protein 2 Sir2 sirtuin (Fragment) OS=Thalassiosira pseudonana GN=THAPSDRAFT_264809 PE=4 SV=1
--------------------------------------LCKSIIVLAGAGMSVSSGIPDFRSAGGLYDTLRPELLLDKGMFLRNPLPMLELKRDF--ILG
ESRWKATLAHRFVELLHSKLGKLTRWYTQNIDGLEMQCKTEKVVPVHGSMGQAACEYCEAPVDFDEFCSIRVVCEECGH-PTVKPTIVLFRGMPKEFVRT
AEDLPECDLLIIIGTSLTVAPANSLVYRVPPTSLR-LVMNNERVGEDSVRDVFAHGHSDEMCLELADRL----------
>tr|L8WVS3|L8WVS3_THACA Hst3 protein OS=Thanatephorus cucumeris (strain AG1-IA) GN=AG1IA_05520 PE=4 SV=1
------------------------------RDVYQAINDARRIVVLCGAGISVHAGIPDFRSPNGLFQSLHPRDLFDAAIFKQSEETMAMFYKMISHLAT
SDAAQPTPFHEMLHSLDAR-GQLLRVYTQNIDALEERAGLPRCVPLHGTLKHLYCPSCYFTLPLCAPLGNSLACPQCAEVARLRPGVVLYNEPHREAERV
RKKRSGEDLLIVAGTSLRIPGAKRIVREFSKTAVKTVYLNFDFVEWDGVFDVWVQGDIQMFARGFE-------------
>tr|X8JNZ0|X8JNZ0_9HOMO NAD-dependent deacetylase Hst4 OS=Rhizoctonia solani AG-3 Rhs1AP GN=RSOL_493760 PE=4 SV=1
------------------------------QDVYQAMNDARRIVVLCGAGISVHAGIPDFRSPSGLFQSLHPRDLFDATVFK-SEETTALFYKMISHLAT
SDAAQPTPFHDMLRGLDAR-GQLLRVYTQNIDALEERAGLPRCVPLHGTLKNLYCPSCYLTLPLCKPLGNPLACPQCTEVARLRPGVVLYNEPHREAERV
RKRRGGDDLLIVAGTSLRIPGAKRIVREFAKPAVKTVYLNLEFVEWDGVFDVWVQGDVQTFARGFE-------------
>tr|M5G455|M5G455_DACSP DHS-like NAD/FAD-binding domain-containing protein OS=Dacryopinax sp. (strain DJM 731) GN=DACRYDRAFT_114334 PE=4 SV=1
------------------------------REVAQAIACGKRVVVVCGAGVSVAAGIPDFRSPAGLFKTLNPKDVFDTRVFQ-SPQSLSLFNRTMSALAS
SAHAQPTSFHSLLRHLEDR-GKLLRVYTQNIDALEEKAGLPRCIPVHGTLRSLYCVSCGYSTPLRP-LGTAPSCPKCAEIGRLRPSVVLYGEEHNE--VV
AKQSRRPDVLVVVGTSLQVPGTRRIVKEFSKEPIKTVYVNFDYTDWEGVFDVWIQGDAQVFAAAVL-------------
>tr|D2VN87|D2VN87_NAEGR Silent information regulator family protein OS=Naegleria gruberi GN=NAEGRDRAFT_70408 PE=4 SV=1
------------------------------KQMADLIKNSKHCCIYSGAGISTSAKIPDYRGPKGCWTLTN-EGKA-------NEI----------KNIE
IEQALPTFTHYAVSHLVKI-GLVKFVISTNVDGLHRRSGLAHLSELHGNCFLEVCKKCKKEYLRGYDVLTGSLCESCG--GELIDTIVHFNETPPELESA
ISHSEKCDLSIVLGTSMLVNPAAQLPKMNV--NNLMCIVNLQKTPYDKQSNVRVFSKTDLFMTLLMTELQE--------
>tr|S3D239|S3D239_GLAL2 DHS-like NAD/FAD-binding protein OS=Glarea lozoyensis (strain ATCC 20868 / MF5171) GN=GLAREA_11947 PE=4 SV=1
--------------------------------------DPKSTVVLSGAGISVASGLADYRGTNGTYRVYRP---IYYHEFLASHEARKRYWA--RSFLG
WTKARPNIAHYAVKNLGDM-GFVRSVVTQNVDSFHSIAHPEPTLELHGYLRALTCVTCHNDLPRAADVFRYPACPHCLAAGILKPAVVMFGESIAVKEAA
EEAIDGSGRLLILGTSLATYSAWRLAKRAKERGMPIGILNLGGVRGEELFDCRVEMGTDKVLPDLVNQLRRT-------
>tr|D8Q1N0|D8Q1N0_SCHCM Putative uncharacterized protein OS=Schizophyllum commune (strain H4-8 / FGSC 9210) GN=SCHCODRAFT_256939 PE=4 SV=1
--------------------------------------APGDVTVITGAGISVDSGIRAYRGHDGRYMNPDYKPIFYHELV--DPTPVQRYWL--RSYLG
YRDALPNTSHYALAALQHS-SIVTRLVTQNVDGLHHRALPERILELHGTLHQVRCRRGHLFQDWKEDFFVIPECPTCLQNNVHKPEVIFFGESIPYKERS
IHDVEHASRVMLIGTTLATYSAFRLVKHALELKKPVLLLNVGPTRADGLPVEKIEIASGAILRDVVRLVL---------
>tr|F1KYN2|F1KYN2_ASCSU NAD-dependent deacetylase sirtuin-7 OS=Ascaris suum GN=ASU_14160 PE=2 SV=1
------------------------------KKLANFLRNSKCTLVYTGAGISTAASIPDYRGPNGVWTLAE-KGITVS--KCGDPV--------------
--QSCPTTSHMVLKEMCRR-GIVRHILSQNCDGLHLRSGVKMLSEIHGNMHIEVCTRCDPPFIRPFDVTTGRVCTVCN--TELVDTIVHFGEVPWNWRGV
TSLIDECDLILCVGTSLAVLKQYQFLWPKTKSHTQIAIVNLQWTPKDRFSCLKINAKCDTVFEKLAKMLS---------
>tr|A0A0M3IYC5|A0A0M3IYC5_ANISI Uncharacterized protein OS=Anisakis simplex PE=4 SV=1
------------------------------KKLASYLRNSKCTLVYTGAGISTAASIPDYRGPNGVWTLAE-KGIAHS--KCGDPI--------------
--ECCPTTSHMVLKEFCRR-GIIRHILSQNCDGLHLRSGLKMLSEIHGNMHIEVCTHCDPPFIRPFDVTTGRACTVCN--TELVDTIVHFGEVPWNWKGV
TSLIDECDLIVCVGTSLAVLKQYQFLWPKAKGQTQIAIVNLQWTPKDRSACLKINARCDTVFEKLAKLFS---------
>tr|A0A0L0DH15|A0A0L0DH15_THETB Sir2 family protein OS=Thecamonas trahens ATCC 50062 GN=AMSG_07623 PE=4 SV=1
-------------------------------------RGGGRLLVITGAGCSTDSGVPDYRSPSGEYN---P---IQYKEFLEEPATRVRYWAR--SFMG
FQAAEPNAIHAALAAWQQNKGANVQIVTQNVDSLHLQAGSEALLELHGHLREVECLGCGAREPREADLFAVPPCPSCGASAARKPSV-------PVAERS
IELAESADALLVVGSTLSTFSALRLARRVAQRRRPIGLVNIGPTRADTLPVLKYEALASALIPRL--------------
>tr|F2UGQ4|F2UGQ4_SALR5 Putative uncharacterized protein OS=Salpingoeca rosetta (strain ATCC 50818 / BSB-021) GN=PTSG_07922 PE=4 SV=1
--------------------------------------QGKPVVIFTGAGISTAAKIPDYRGPNGVWTRRDR-GLP-------PPKS--------R---G
FDGAKPTFTHRVIVSMLES-NLADYIVSQNVDGLHLKSGVNQISELHGNSFKETCVDCERTYLREHSVITGRACEHCRKQGMLRDSIIHFGESLPALATA
EHMCRRAGVVLCIGSSLHVTPAADLPILCEQVGGHMHIVNLQQTGRDDEGGVVVHEKCDKVMFLVASHL----------
>tr|A0A0L0DPU8|A0A0L0DPU8_THETB Transcriptional regulator OS=Thecamonas trahens ATCC 50062 GN=AMSG_10302 PE=4 SV=1
--------------------------------------ADGETVIFTGAGISTSCGIPDFRSPNGVWTLKA-Q------GR------------KRKKTTP
TTKAIPSATHMGIVAMLRS-GTAKFLISQNCDGLHRRSGVAKLAELHGNSNIEYCRSCGAEYLRDRDHFTGRHCERAGCGGKLWDSTIDFGQSLPPLRAA
YAASQTAALHIVFGSSLTVSPACDMPAETAAAGGRMVIVNLQKTPLTENADLHIYAKTDDVMCALLSQLG---------
>tr|A0A099NT93|A0A099NT93_PICKU Uncharacterized protein OS=Pichia kudriavzevii GN=JL09_g4802 PE=4 SV=1
-------------------------------DILQCINKSRKIAILTGAGISCNAGIPDFRSDNGLYNKKKGKDMFDVSVYRSTVEIFNNFIYELYQQVL
--QCKPTRTHEFIRKLNDK-NKLIKCYTQNIDGLERNCGLSDVIQLHGDLHQLCCNSCKFSYQWNEDISNLIECPKCVNIGIIRPNIVLYGEEHPYSENL
NKLNKKPNILLIFGTSLKVEGVKNLVRKMSKDKGMVILVNKDPISQSNYIDFQVVSDCDAFC-----------------
>tr|L0B0Q8|L0B0Q8_BABEQ Transcriptional regulator, Sir2 family domain-containing protein OS=Babesia equi strain WA GN=BEWA_002530 PE=4 SV=1
-------YASRLKKNDNKGPLGTLQLFDTPTDVHQLLSASDNAILHTGAGVSTGAGIPDFRGPSGVWTIMKKRSVTSDCVFRTNSKLSVTYGRKRKEAVE
FVLALPSEAHLAILELLKA-GVVKFIITQNIDGLHPLSGVSQLAELHGNVFTERCISCGRRYQRPYVAFTGETCGICSFSGVLTDVVLWFDKYEEHYNKA
VEVSRAADLHVSLGTSLHIEPACHYASIDRNPDSPLVIVNFQKTKLDPEANEVIHSDVNKLFISLLKRF----------
>tr|A0A0N5ATV5|A0A0N5ATV5_9BILA Uncharacterized protein OS=Syphacia muris PE=4 SV=1
-------------------------------KLAEYMKASKCTLVYTGAGISTSAKIPDYRGPNGVWTLAEGIEVK----KCADPV--------------
--ECSPTTSHMVLKEMCRR-GMVRHILSQNCDGLHLRSGVKMLSEIHGNMHIEVCSNCNPQYVRSFDVNTGRNCTVCN--AELQDTIVHFGERPWNWNGV
VGLVDQCDLILCLGTSMAVLKEYQFLWPKPRSNTKIAIVNLQWTPKDRASCLKINAKCDLVLENLAKLL----------
>tr|N1JA76|N1JA76_BLUG1 NAD-dependent deacetylase OS=Blumeria graminis f. sp. hordei (strain DH14) GN=BGHDH14_bgh06318 PE=4 SV=1
--------------------------SFELQQIADTLAKSRKVVVLTGAGISTNCGIPDFRSEDGLYSLSSPNELKTPRTIWSDPLKFYMFISSFRERIK
-SIKSTSETHHFLRQLRDS-GRLVRTYTQNIDCLEEKEGLSETVLLHGSLSALRCGLCSQLCNWDEDGGSAPDCPHCIAVGRLRPDIVLYGEEHPNSSLV
THDLKCPDILLVMGTSLRVHGLKVIVKEFHSKGGKVVFVNKTGPSEANIIDYWVDWDCDEWVLDLKER-----------
>tr|E1F2G4|E1F2G4_GIAIA Transcriptional regulator, Sir2 family OS=Giardia intestinalis (strain P15) GN=GLP15_3933 PE=4 SV=1
------------------------------LHLARTLRTGQAVVFVTGAGLSYASGITPYRYSKAIWSNF-VMASGERRTFKEDPDQYWNSFWLRTHEIP
FINAKPNQGHIAIAKIMRK--ADAFVITQNIDTLHTKSGANRLVEIHGRLGLYKCVNQDCPYSRSISIIKIPRCPGCL--SPIMPHALMFDEQYHRYYEA
EQWLRAADAIVFVGTSFSVNITQDAINIALERDIELYSFNIAQEKIDSLELQWIIGPSEETLPLLDRILTELMS-----
>tr|F0Z6Q6|F0Z6Q6_DICPU Putative uncharacterized protein OS=Dictyostelium purpureum GN=DICPUDRAFT_85737 PE=4 SV=1
------------------------------ESLAKEMLSGKKVLFITGAGLSISSGISPYRNSNAIWGSF-ITTWGTRKKFIEDPQSFYNVFWLRTHEKQ
YLDALPNPGHLSITNFVEL--CNANVITQNVDELHLKAKVSKLIEIHGRISMYKCITKNCTYEYDETIINPPPCPSCS--NPILPQSLLFDEDYHRYHEA
MDWIEEADIVVFIGTSFSVGITEEVVYQAQTNNKKMYNFNVFKTKV--KNMRPIIGPSEITLPLLERQFLYEAQ-----
>tr|A0A058ZC32|A0A058ZC32_9EUKA Uncharacterized protein OS=Fonticula alba GN=H696_02433 PE=4 SV=1
--------------------------------------PAHRAVAVLGAGISTSSGIPDFRSLTGVYEQARGQDLFDASVFY-DPERTRDFLRLMAVLAQ
SRRASPTPVHKFLRELEGE-GKLLRAYTQNIDKLERKAGLRTVVELHGTLDTVYCTLCHETFPLVEDLLGFPVCPACKAVGRLRPSVVLYNESHPRAEDV
ERALDQPTLLMVMGTSLKVDGCRHLVRQLRNNGGISLYFDNSPPEWLGIFDWHIMGDLDQAV-----------------
>tr|A0A061B833|A0A061B833_CYBFA CYFA0S21e02124g1_1 OS=Cyberlindnera fabianii GN=CYFA0S_21e02124g PE=4 SV=1
----------SHTKQKRKPKLRYRPNISEQDDEIYAFKYSKKMTVVTGAGISVASGIPDFRSSNGLFQGLKSKALFDSSVYS-DGETTAMFHAMINQLYD
TENSKPTDFHKIMDTVSSE-GRLLRHYTQNIDCLEAQLPNPPTIQLHGTIKHMYCSKCRWSSEMDPHLNEAPACPECEEIGCLRPRIVLYNELHPDGEHI
LDLKSKPDCLIIAGTSLKIPGVRRLVKELAAVNGCVIWINRDEPSMDQYIDLIITGDCQD-IPSIVDNYDR--------
>tr|A0A0H5CGU1|A0A0H5CGU1_CYBJA HST4 protein OS=Cyberlindnera jadinii GN=HST4 PE=4 SV=1
----------KALKTKRKPKLQYRPAISEQDDLVYAIKHSKRMCVVTGAGISVASGIPDFRSSNGLFQGLKSKALFDSSVYN-DGESTAKFHAMVNTLHE
TSMSKPTEFHRMMDHVSED-GRLLRHYTQNIDCLENQLEHPPTIQLHGTIRHMYCAKCRWNSELEPQLSEPPACPECLEVGCLRPRIVLYNEFHPDGENI
SDLRSKPDCLIIAGTSLKIPGVRRLCKELAASNGCVIWINRDQPSVDEFIDLIVMGDCEN-VPKVVANYDS--------
>tr|K0KHH8|K0KHH8_WICCF NAD-dependent deacetylase hst4 OS=Wickerhamomyces ciferrii (strain F-60-10 / ATCC 14091 / CBS 111 / JCM 3599 / NBRC 0793 / NRRL
----------VVTKPKRKPRMKYRPEILDQDDLIYALKYSRKITCVTGAGISVASGIPDFRSSNGLFQGLKSKALFDSNVYR-DYESTAKFHAMIRQLYE
TNESEPTDFHKMLNDISKD-GRLLRLYTQNIDCLETDLSDPPTIQLHGTIKYMYCSKCRWNSTLQPELNEAPACPECTEIGCLRPRIVLYNEFHPDGEHI
LDLKSKPDCLIIAGTSLKIPGVRKLVRELAAARGCVIWVNVDEPTVDEHIDLIVTGDCQN-IPKIVDSYDQ--------
>tr|Q0D1D9|Q0D1D9_ASPTN Putative uncharacterized protein OS=Aspergillus terreus (strain NIH 2624 / FGSC A1156) GN=ATEG_00245 PE=4 SV=1
------------------------------DLLTKTIRRHRKIVVIAGAGISTSAGIPDFRSTDGLFKSLQAKLLFDAA-VYQDENLTASFQDMVRSLSE
AAKTSPTAFHHMLARLGQE-GRLTRLYTQNIDGIETSMPWPRTIQLHGSLDKVVCQKCRHLTDFDSAMPDAPECPECSRVGKMRPRIVLYNEHPDAITSV
MNIRSRPDALIVVGTSLKIPGVRRLVKSLRRRNGVTMWINNEPPVFEDCWDLMVKGNCEEVA-----------------
>tr|R7QBA3|R7QBA3_CHOCR Uncharacterized protein OS=Chondrus crispus GN=CHC_T00003572001 PE=4 SV=1
----------------------------------RRIRSSSHVVLHTGAGISTSAGIRDFRGPKGVWTTESSRAK-TTD--KQDGA---------SNTC-
FEDAVPTLTHMAITAMHAM-GFIHYVISQNVDGLHLRSGLSALSELHGNLFVDWCPVCKSETRRDSEVPSGKRCGRCD--GMLTDKALDWDDALPDLELA
REHGDKADLAVVVGTSCQMDPARGLPFRGK---GDVVIVNLSRTDYDKRAAFTVRAQTDAVFA----------------
>tr|G7Y848|G7Y848_CLOSI Phosphatidylinositol glycan class Z OS=Clonorchis sinensis GN=CLF_102563 PE=4 SV=1
----------------------------------RLMVESAYTVVHTGAGISTPVGIPDFRGPKGVWTLEKL---------GEKPTVSV----------S
FEKAMPSLAHRILVELERK-NLIQYLITQNIDGLHFRSGFNRLSILHGDMFLEVCDTCGSFFARSTPVFTKPSGRGCR--GRLCDTILDWESDLPDYHLA
IEHSNRADLHICIGTSLQMYPAASLPLLPRRHRSKLVIINLQKTKLSKRANLNIHAPADVVLDAIAKKFH---------
>tr|K8F489|K8F489_9CHLO NAD-dependent deacetylase sirtuin-6 OS=Bathycoccus prasinos GN=Bathy09g00290 PE=4 SV=1
-------------------------------------KKKTGVIVHTGAGISTAAGIPDFRGPKGIWTLQKAENLPTS-------------------SVP
FPLASPTVTHMVLCGLQKA-GYIRYVVSCNVDGLHYRSGIEEVGELHGNCFAERCETCECEYFRDFEMETGRRCRRCA--GKLRDQVLDWDDALPELCRA
ENEAKKAKLALVLGSSLQIVPSGDLPLLTRTTGGQLAIVNLQATEKDQFADLVVHAKTDQVMLQVAKYLN---------
>tr|T1JMX0|T1JMX0_STRMM Uncharacterized protein OS=Strigamia maritima PE=4 SV=1
--------------------------------LAEFIRNTNRLVIYTGAGISTAASIPDYRGPNGVWTLMQKKKIGS-------------------HELS
--DAEPTTTHMVVAQLYDK-GILSHVVSQNCDGLHMRSGLPVLSEVHGNMYMEVCIKCRPEYIRLFDVKTGRKCYECG--NDLIDTIVHFGEKLPNWLGA
VKAAEKCDMILCLGSSLKVLRKYTCLWEMNRSRPVLCVVNLQWTPKDHVATLKINGKCDEVMVEMMKQLQ---------
>tr|L8HMR6|L8HMR6_ACACA Transcriptional regulator, Sir2 family protein OS=Acanthamoeba castellanii str. Neff GN=ACA1_084880 PE=4 SV=1
------------------------------DRLAKMVKQSKYTVFFTGAGVSTSAGVGDYRGPSGAWTKRKIKELLGAGRTAEDESELTKLKAKARVKID
MCDAQPTPTHMAMATLIR-LGLAHYVVTTNLDGIYRKAGLEQLCCLHGDIYVERCSGCGYDFERNYHVHKVGTCSRCGSGGGTKDTHINFGELLDDWNEA
DTHCRRADLCIIAGTSMSLRHITHFPFLAR----QVVLINLQPTPDDDEATLRIWAKCDPVFEGLMARLD---------
>tr|W7U2V3|W7U2V3_9STRA Transcriptional sir2 family OS=Nannochloropsis gaditana GN=Naga_100010g71 PE=4 SV=1
--------------------------------LAHFIQEKKKIAFLVGAGLSAASGVPVFRGENAIWVKR-VTSMGTKAAFLRDPVTWYEFWFPFKHQYT
--RASPNAGHEALARLSNL-DPNLLVVTQNIDSLNRQTRQDKLVEIHGRLGLYHCSSNNYCETWAQALTHVPRCTECGT-GYMMPLALMFDEMYDQSDKA
LAAFEEADALVFVGTSFQV-NISNLAIEARKRGIPIFNFNIRDGLAKRYDVFNIIGPAEETLQKLLEQVEACLEKDSL-
>tr|D2UZP8|D2UZP8_NAEGR Silent information regulator family protein OS=Naegleria gruberi GN=NAEGRDRAFT_62017 PE=4 SV=1
--------------------------------------HKGKICLFTGAGISSSAGLKTYRGKDGIWLKQDDTTK------NSNDS----------DNL-
--KYFPTLTHMSIKKLYDM-GYIKYIITQNSDNLHWKSGISDTIEIHGNSYKEHCEKCDKTFIRQDDHLTVNKCEQCG--GPLKDLIVNFGEKLKLWKKA
VKFVENSTLVLAVGTKLSVEPVNSLVTMND--DHKLIICNLQLTPFNDNANLVIRCKSDELFSRLMGKVIDN-------
>tr|B0WK67|B0WK67_CULQU Chromatin regulatory protein sir2 OS=Culex quinquefasciatus GN=CpipJ_CPIJ006726 PE=4 SV=1
--------------------------------LAQAIARSNHLVVYTGAGISTSAKIPDYRGSQGIWTLLAGKDIG--------------EYD-------
LSLADPTYTHMALFELHRR-GILKHVVSQNCDGLHLRSGLRSLSEVHGNMYVEVCKSCKPNVYWRFDHNTNRRCRKCG--KPLVDTIVHFGERLWNWAGV
TPHTQKTDAILCLGSSLKVLRKYTWLWAMDKKRPKLFIINLQWTPKDNVSSIKLNGKCDEVMRLVMKHLN---------
>tr|A0A0L0VMP4|A0A0L0VMP4_9BASI Uncharacterized protein OS=Puccinia striiformis f. sp. tritici PST-78 GN=PSTG_06478 PE=4 SV=1
------------------------------QRAIKAVLNAKRVAVVVGAGISTSANIPDFRSSTGLFASLSGRDLFDVNAWK-DPDTLSGMLAELHKMCG
--AAQPTAFHQFLKRLDDD-GKLSRVYTQNIDGLEEKAGLPRVIPLHGTLKNLSCLTCKHSVLMSDYIGEPILCPQCQSVGLLKSGVVLYGEEHNAGDTS
RDLLRRPDLLIVAGTSLKVPGTKRLVKELSKKPIHTIFLNNEFAPWKETFDVWIKGNVDQFIRL---------------
>tr|F4RTA4|F4RTA4_MELLP Putative uncharacterized protein OS=Melampsora larici-populina (strain 98AG31 / pathotype 3-4-7) GN=MELLADRAFT_117100 PE=4 SV=1
------------------------------KRAIKAVLSAKKIAVVVGAGISTAANIPDFRSSTGLFASLSGRDLFDINAWK-DPETCSGMLAELHGVCE
--KAQPTKFHEFLKNLDEE-GKLSRVYTQNIDGLEEKAGLPRVIPLHGTLKHLTCSVCKSTELMSDYIGELIYCSQCETVGVLKSGVVLYGEEHKEGETS
RDLMRRPDLLIVAGTSLKVPGTKRLVKELSKKPIHTIFLNNEFSPWKDTFDVWVKGDLVKFIEM---------------
>tr|R1EY06|R1EY06_EMIHU Uncharacterized protein OS=Emiliania huxleyi GN=EMIHUDRAFT_450371 PE=4 SV=1
------------------------------EAFAQRLARARQVIVMLGAGASVSAGIPDFRSPTGLYSQLFPEAVFDLTFFADNPRP---FYRLAKE-LW
PGNHAPTPAHHFISLLAAR-GILRRCYTQNIDSLESAAGVPLTVAAHGNFDAAHAWSASRPLLWQGEEAVEALNEESG--GLVKPDIVFFGEQLPRFGRL
PADFDACDLLLVMGTSLQARD------------VPRLLINREPTGADPPRDAFFEGDCDAGVTELAR------------
>tr|A0A0D2CMR4|A0A0D2CMR4_9EURO Uncharacterized protein OS=Exophiala xenobiotica GN=PV05_09914 PE=4 SV=1
------------------------------EELAATLRESQRIVCVAGAGISTSAGIPDFRSAQGLFVRLSGKEILSASVYEHESAALHSFVRNFIELV-
-DAARPTPFHHFLDRIAAK-GKLQRLFTMNIDDLDVSIPPPKTIQLHGTISKMECTKCHRISNLDRALFSMPLCPRCSRKHGLRPRFTLYDESVRAIGNA
EEDKSRPDLVLVVGTSLQIPSVTRLIHKFG-HFAKLLWINIEPPPEPFGFDYIYRAPCDDFARWISTE-----------
>tr|D2V3E2|D2V3E2_NAEGR Predicted protein OS=Naegleria gruberi GN=NAEGRDRAFT_30659 PE=4 SV=1
------------------------------QKLAGQLASGKKLLFVTGAGISQISGIPTYRGDNSIWSNH-ILDMGTRKMFQRDELHWYSFWLHKREYF-
--VAKPNEGHLAIARLSKL--CNLRCITQNIDHLHSKTSLSHIIEVHGRLGLYKCINSRKKYAKDTTIKSVPKCPFCK--TLLLPQALLFDEKYDQWRKA
LQWIADCEVICFVGTSFSVGVTAECLSIAKDNDKTLYNFNIRVDKEKNPGMYHIVGKSEISLPFLFNTLVE--------
>tr|T1IZX7|T1IZX7_STRMM Uncharacterized protein OS=Strigamia maritima PE=4 SV=1
----------------------YSTNVWSVDDAVQLIKAVEKIVVMAGAGISTPSGLPDFRYPTGLYSQLYAEAIFDILYFENDQRP---FFDLAQELY-
PGNYRPNITHYFVRLLQEKI---------NYYGL---AGIDLLIEAHGTFSVATCIKCRQTYDGEEDIMLIPKCTKCK--AVIKPDIVFFGEQPPRFTHL
-IDMPECDMLIVMGTSLEVEPFASCAEAVA-QLTPRLLINQDAVGVDSATDVVLEGDLVKNVELLVQK-----------
>tr|L0PAA5|L0PAA5_PNEJ8 Uncharacterized protein OS=Pneumocystis jiroveci (strain SE8) GN=PNEJI1_003459 PE=4 SV=1
-------------------------------------TKSKKVVVFVGAGISTGAGIPDFRSENGLFASIMGQDLFDVS----NDENIQQFHTMISDLYR
SASAKPTLFHQYIAALARS-SRLMRLYTQNIDFLETRMPCPKTIQLHGGLQNMICSKCCWVGPFDPDIFTLPSCQQCIEVGKLRPRIVLYNEYLDAIGTT
YDLKEKPDALIVAGTSLKIASARRIVREMKASHGITIWINTTDFEFENKFDIIVKGDCQKIAN----------------
>tr|M7NQV3|M7NQV3_PNEMU Uncharacterized protein OS=Pneumocystis murina (strain B123) GN=PNEG_02080 PE=4 SV=1
-------------------------------------TKSKKVVVFVGAGISTGAGIPDFRSENGLFATLSGQDLFDISVY-KNENDMKRFHKMISDLYR
SASAKPTLFHEYLAALARS-SQLIRLYTQNIDFLETRMPYPKTIQLHGGLQNMICSKCYWTGPYDPDIFSLSVCHQCIEVGKLRPRIVLYNEYLDAIGTE
YDLKEKPDALIVAGTSLKIAGARKIVREMKASHGVTIWINTSDFEFEKKFDIVIKGDCQKVAD----------------
>tr|M1VDT0|M1VDT0_CYAME NAD-dependent deacetylase sirtuin 6 OS=Cyanidioschyzon merolae GN=CYME_CMM136C PE=4 SV=1
--------------------------------LAQWLRACGDVVVHTGAGVSTAAGVRDFRGPHGVWSEASRPGVAPGEPLTRDGARCADVIDPRTQDCS
LELAAPTWSHWALTELVRR-GLVRRIVTQNIDGLHLRSGLHRLSELHGNIFAEQCERCGQIFLNDVVVRTGHQCVYCAQRASTRDMLLDWEDPLPDLMGA
TEDSRNARLCLVMGSSLQMVPAATLPALCLKDGARLVIVNASWTARDDAAHLVIRAPTDMVMLLLLDELA---------
>tr|A0A084QWX6|A0A084QWX6_9HYPO Uncharacterized protein OS=Stachybotrys chlorohalonata IBT 40285 GN=S40285_09498 PE=4 SV=1
------------------------------ERLVTALRKKKKIVVIAGAGISVSAGIPDFRSSTGLFATVSGEQLFDASLYNHNET-TESFHTMIREIAK
TENAKPTPFHHFLASLAQE-GRLMRLYSQNIDCIDTKMKPPATIQLHGSLQYMVCTKCGSLKLFEAELFETPLCEDCVLIGRLRPRLVLYNEYPDAMVSS
ADLKTCPDAVVVVGTSLRVPGTRRLVKELCRNNGFTAWINIDSEPKKDCWDLVVRAKCDDIA-----------------
>tr|A0A0C2WJT9|A0A0C2WJT9_AMAMU Uncharacterized protein OS=Amanita muscaria Koide BX008 GN=M378DRAFT_172726 PE=4 SV=1
----------------------------------AVLKQAKNIVVLAGSGLSAASGLPTFYDTDGRWGYYSLMSIGSPRAFHENPSQFWKICHYYREAAR
--HAIPSSAHKAIALLCSSEASKFCLVTRNIDNLSNRALSSLAIEMCGNIFTVNCTNCNLTWNFDIDIKELPTCSRCS--GLLRPGVTWLDRHVDLQVRS
-IILRQCDLVLIVGMAPFFMST--FLEQDGRNNRKVAVFNIKPPSG-IEADFVFLGPCQETLIKALD------------
>tr|A0A0J9XBY8|A0A0J9XBY8_GEOCN Similar to Saccharomyces cerevisiae YDR191W HST4 Member of the Sir2 family of NAD(+)-dependent protein deacetylase OS=Geotrichum candidum GN=BN980_GECA08s03321g PE=4 SV=1
-----------------------------------VFKHSRRLVVITGAGISVSSGIPDFRSTTGLFTLLSGKQMFDASVVYNDTTSTQNFHTTIHDLC-
-SKSEPTPFHKCINEISKD-KRLLRLYSQNIDCLDANMSHPTTIQLHGSIQKMNCTKCNWMGDFDASVDVAPECPECKEIGRLRPRVVLYNEFPDAIGQV
ADLTSRPDGLIVVGTTLKIPGVRRLVREMSAKGA-TVWMNIDDPPQEGCFDLIVKGDCQ-IIPQLMADY----------
>tr|M5C300|M5C300_THACB Uncharacterized protein OS=Thanatephorus cucumeris (strain AG1-IB / isolate 7/3/14) GN=HST3 PE=4 SV=1
-------------------------------------GAVSHVVVVSSAGISTNAGIPDFRSADGLYNKAGFSELLGPEMFDADREKLLH-YGRAMGALR
SKRTSPTACHNYIAKLHEH-GRLLHCYTQNVDGLQTSAG--RVLELHGNIHHIQCNRCGQPPDENPDVDGYVKCKKCGKPGLLLPKVLH-NEGSWFMDEL
EQTDSIASLLYILGTSIRTDGAAKLIRALHNNNGIVVYVDRQILKLASYFDLQIESD----------------------
>tr|A0A0G4EN53|A0A0G4EN53_9ALVE Uncharacterized protein OS=Vitrella brassicaformis CCMP3155 GN=Vbra_12509 PE=4 SV=1
-------------------------------RLADLIRRAESVVVHTGAGISTTCGIADFRGPSGVWTLQKKVELG-AET---HK---VRFGDEERDAVD
FEKAIPSYGHQFICDLWRA-GRLRYLITQNVDSLHARTGGDVMAEVHGNVCMERCEDCGRRFLRDYQMTTGHKCHICSYPGECV-DVLDWEDNLERYSKS
EKMSRDAELNLCLGTSLRMDPAGQWPMNAKNRNAKLAIVNIQRTSLHDEADLVIHSPIDTVLEAVAAKLH---------
>tr|G4TXD8|G4TXD8_PIRID Related to HST4-member of the Sir2p family of NAD(+)-dependent histone deacetylases OS=Piriformospora indica (strain DSM 11827) GN=PIIN_09981 PE=4 SV=1
----------------SKLRQPKDHAL-QLERAARTIAKARRVVVVCGAGISVQAGIPDFRSSTGLFQQLNPKELFDAQHVFHSESTASVFYKMVARLIM
ADEAHPTPFHRLLKGLDDR-GQLLRCYTQNIDGIEERAGLPRCIPLHGTLKTLHCASCGNTSPLREHVGTAPSCSQCSEVGVMRPSIVLYNEDHREGEKV
RQRRAPPDLLIVAGTSLKVPGTKRIVKE---------------------------------------------------
>tr|K1W565|K1W565_MARBU Sir2 family histone deacetylase OS=Marssonina brunnea f. sp. multigermtubi (strain MB_m1) GN=MBM_09794 PE=4 SV=1
------------------------------RRLIDALRTKRKIVVIAGAGISVSAGIPDFRSSTGLFKTMSGKDLFDAGVYRNNDST-SAFHDMVRELSH
TKNAKPTPFHHMLATLAEE-GRLMRLYTQNVDGIDTALGPPQTIQLHGGLEKMVCSKCGEISNFEGKLPEAPLCSECSEIGRLRPRMVLYNEYPDAIGSA
WDLKKGPDAVIVVGTRLTIPGTKRLTKELAKRGGFTAWINLEADPAGDCWDMIVKAECDT-------------------
>tr|A0A0G2EKY7|A0A0G2EKY7_9EURO Putative hst3 protein OS=Phaeomoniella chlamydospora GN=UCRPC4_g02880 PE=4 SV=1
---------------------------------------------VTGAGISTSLGIPDFRSKDGLYSLITPSDIASSKRVWKNPESTSTFYTSLRKQIH
QEVKQTSQTHKFIRVLRD-GGRLMRCYTQNIDGLESREGLSEVVPLHGDLDKLRCNLCQKLADWTDALGEAPPCQACSSVGLLRPNIVLYQEQHPQLAPS
FDMAHGPNVLIIMGTSLKVHGLQNLVREFAKKDGRVIFVNRTKPSENDFIDDWIEMDCDDWISDL--------------
>tr|A0A0L0CKB7|A0A0L0CKB7_LUCCU NAD-dependent protein deacetylase Sirt7 OS=Lucilia cuprina GN=FF38_08499 PE=3 SV=1
-----------------------------------IILQAKHLICYTGAGISTAALIPDYRGSKGIWTLLQGEEIGDH-------------------DLS
--AANPTYTHMALYELHRR-GILRYVVSQNCDGLHLRSGLPSLSEIHGNMYVEVCKNCKPNVYWRLDMKTNRLCHKCS--EPLCDTIVHFGERLWNWAGA
CHHAEKADVILCLGSSLKVLKKYTWLWQMDRQRAKICIVNLQWTPKDTLAQVKINGKCDRVMEMLMNALK---------
>tr|Q23A43|Q23A43_TETTS Uncharacterized protein OS=Tetrahymena thermophila (strain SB210) GN=TTHERM_00833750 PE=4 SV=1
------------------------------QEGAQLFKDKKKVVFLTGAGISVASGIPTFRGVGPLFEKYQNEEISTYNFMKNKPDIFWERNL---IFLG
QLGKKYNVSHLKIQQLVNQYGPQAVIVTQNTDGLHCQAFCPDVFEVHGSKTFLRCDNCKDKYPQKYNSYKDFICETCK--TQARPNVLYFDESYNRINTL
KELTSDMDLLISIGTQLDTGYAAQTVSSAVQQKIPVIEISLTPVI--QKGGLTLKGKAEEVVPQLCDLVMELN------
>tr|B7G8W4|B7G8W4_PHATC Predicted protein OS=Phaeodactylum tricornutum (strain CCAP 1055/1) GN=PHATRDRAFT_39523 PE=4 SV=1
------------------------------LELAERLVEGQEVVIITGAGLSVASGIRPFRSTNGLWNDV-IWTTATREAFRKDPKR---WYNDFWPHFQ
DTTYYPNAGHLALQALHDRY-ENLRQITQNIDGLQEPN--NHLIEAHGRVGLYKCIPHEDEESSDDEIPEAPACPACG--GDVLPQALLFDEGYYDFERA
EAWLESAEAIVFCGTSFAVRITHVALEHARVHKVPVYNFNLHDVLESRLNVTNIIGPSDETLPKLVEACDEA-------
>tr|A0A0J9XCK3|A0A0J9XCK3_GEOCN Similar to Saccharomyces cerevisiae YDR191W HST4 Member of the Sir2 family of NAD(+)-dependent protein deacetylase OS=Geotrichum candidum GN=BN980_GECA09s02155g PE=4 SV=1
----------------------------------HVFKHSKRLVVITGAGISVHAGIPDFRSSTGLFRIYRGKQMFDASIVYNDSTQTKIFHSTLHSLCT
--SSSSTPFHQFINEISAN-NRLLRLYTQNIDCLDTSAASPRTVQLHGSIRYMNCSKCQWTSEFQPSSDSVPECPECLKIGRLRPKVVLYNEFPDVIGQI
TDLTSRPDGLIVVGTSLKIPGVRRMVREMSASKGATIWMNIDDPPQEGCFDLIVKGDCQ-IIPRLLDDYEQE-------
>tr|Q6CB00|Q6CB00_YARLI YALI0C23034p OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=YALI0_C23034g PE=4 SV=1
------------------------------------FHNSQRLVVITGAGISVHAGIPDFRSDKGLFVSYNGKALFDASVFR-EPATTMHFHSAIQKLC-
-QDAKHTPFHHFLNSISEQ-NRLARLYSQNIDCLDTSLPHPTTVQLHGSISKMNCMKCGWMSDLDPELEDMPLCPACVEVGKLRPRIVLYNEFPDAIELS
ESLHSRPDGLIVVGTTLKIPGVKRIVREMAAMNGGVVWLNRDDPPFEGVFDLLVKGDCQL-VPKLLQDFETEQE-----
>tr|A0A0N8Q015|A0A0N8Q015_RHOGW Uncharacterized protein (Fragment) OS=Rhodotorula graminis (strain WP1) GN=RHOBADRAFT_45153 PE=4 SV=1
------------------------------QHVARTVLKAKRIAVVCGAGISTATGIPDFRSGAGLFESYSGKDLFDVGLFQSE-QTASIFYNMIHKQA-
-DGVAPTAFHSWLKQLDND-GKLFRVYTQNIDALEEKAGLPRCIPLHGHLSTLSCSFCKLVTPTAAYLGTAPLCPACLAVGVLRPDVVLYGEEHKDGEEI
QRLGQRPDLLLVVGTTLKVKGTKRLVRELAKAPVHTIYLNAEFSPWADVFDVWCRGDIQEFVAALARE-----------
>tr|W4H106|W4H106_9STRA Uncharacterized protein OS=Aphanomyces astaci GN=H257_03072 PE=4 SV=1
--------------------TLPMAAV---ASAAEKILRADILLVAVGAGFSADSGLPVYKDIALAYHQVDYQDLCDPYWIYDDISIFLGFWGESFNQYR
--NTTPHAGYDILKRWKQRLTSPFFVFTSNVDSHCTRVFANEVYDVHGNTDHWQCAGCCNDWPFDVDSSPLLQCPRCK--GPGRPNVLMFRDKHWIWEDA
VEDVSKRLVVLEIGCGTRV-QDNKTANQSWKAKTTKSSCRPCSKA----------------------------------
>tr|W4H271|W4H271_9STRA Uncharacterized protein OS=Aphanomyces astaci GN=H257_03070 PE=4 SV=1
--------------------AASSSLI---RDAAEKVKGADYLLIMTGAGFSADSGLPVYMDIADAYSKVEYHDLCDPCWIRDDLPVFYGFWGDCFNMYR
--DTTPHAGYEILQRWKARVPDPFFSFTSNVDAHFLKFFQNEVYEIHGNTEHWQCANCSKAWPFEVDAAEGLACPECG--GPARPNVLMFGDADWIWIAR
VQDASKRLVILEIGCGTRV-PSVRIQSEQLRYQAHLIRVNPDMED----------------------------------
>tr|A0A024UBZ8|A0A024UBZ8_9STRA Uncharacterized protein OS=Aphanomyces invadans GN=H310_04865 PE=4 SV=1
--------------------ALPMAAI---VTAAEKILRADILLVAVGAGFSADSGLPVYKDLAQAYYEVDYQDLCDPYWVYEDYSVFLGFWGDSINLYR
--NTTPHPGYDILKRWKERFTAPFFIFTSNVDSHCTRGFANEVYDVHGNTDDWQCAGCSTNLPFDVDTSPMFECPQCK--GPLRPNVLMFRDKHWIWENA
VLEVTKRLVVLEIGCGTRV-HTVRHHCEELEGQATLIRVNPEVDD----------------------------------
>tr|W4GZV3|W4GZV3_9STRA Uncharacterized protein OS=Aphanomyces astaci GN=H257_03071 PE=4 SV=1
--------------------MDDDAAL---GAAADDILSADFLLVAVGAGFSADSGLPVYNDIAAAYKALEYHDLCDAHWAHANLPLFYGFWGDCFNMYR
--DSSGHAGYEILREWKLRLTEPFFVYSSNVDAHFRRMFANEVYEIHGTTERWQCAGCP-GWPFPVDPPPFLECPKCH--GPARPNVLMFGDTSWLWEAA
VEEATKRLVVLEIGCGLRV-PSVRMECEMQCDQVRHIRINPTDID----------------------------------
>tr|W4H038|W4H038_9STRA Uncharacterized protein OS=Aphanomyces astaci GN=H257_03072 PE=4 SV=1
--------------------TLPMAAV---ASAAEKILRADILLVAVGAGFSADSGLPVYKDIALAYHQVDYQDLCDPYWIYDDISIFLGFWGESFNQYR
--NTTPHAGYDILKRWKQRLTSPFFVFTSNVDSHCTRVFANEVYDVHGNTDHWQCAGCCNDWPFDVDSSPLLQCPRCK--GPGRPNVLMFRDKHWIWEDA
VEDVSKRLVVLEIGCGTRV-ETVRENNEELEGQATLIRVNPEVED----------------------------------
>tr|A0A024UB22|A0A024UB22_9STRA Uncharacterized protein OS=Aphanomyces invadans GN=H310_04863 PE=4 SV=1
---------------------MATTKI---REAAEKIRGADYLLIMTGAGFSADSGLPVYMDIADAYNKLEYHDLCDPCWIRDDLPVFYGFWGDCFNMYR
--DTTPHAGYAILQRWKARVPDPFFSFTSNVDAHFLKFFTNEVYEIHGNTENWQCADCSRRWPFNIDAAQGLTCSVCA--GPARPNVLMFNDNNWIWIGH
VQEATKRLVVLEIGCGTRV-PSVRIQSEHIKFQAHLIRVNPVMEP----------------------------------
>tr|A0A024UAI0|A0A024UAI0_9STRA Uncharacterized protein OS=Aphanomyces invadans GN=H310_04864 PE=4 SV=1
----------------------MDAAL---RAAADDVLSADFLLVAVGAGFSADSGLPVYNDIAAAYKAIEYRDLCDAQLAHVNLPLFYGFWGDCFNMYR
--DTKGHAGYDILRKWKELVNDPFFVYSSNVDAHFHQHFSNEVYEIHGTTEYWQCAGCQ-GWPFTVDLPPFLQCPQCH--GPARPNVLMFGDKSWIWEAA
VEEASKRLVVLEIGCGMRV-PSVRMECEMEENQVRHIRINPMDAD----------------------------------
>tr|T0SEK1|T0SEK1_9STRA Uncharacterized protein OS=Saprolegnia diclina VS20 GN=SDRG_01321 PE=4 SV=1
----------------------MDEKC---RQAAALIRDADFIMIAAGAGFSADSGLPVYNDIAEAYNTVDYQDLCDPYWIHEDLKLFYGFWGDCLNMYR
--STTPHRGYQILQKWKQRVGDPFFIYTSNVDHHFTQFFSSEIYEIHGNIELWQCAGCSASWPFEIDRDPLLSCSTCR--GPARPNILMFSDRKWIWEAA
MEEVEKKVVVIEMGCGMRV-PSVRHECEMLKRQANLIRINPDTSD----------------------------------
>tr|A0A059F0A5|A0A059F0A5_9MICR Uncharacterized protein OS=Anncaliia algerae PRA339 GN=H312_02046 PE=4 SV=1
---------------------------------------NKKCVVITGAGISVSAGIPDFRSKEGIFSHYNGTELFSYS-FGLNPSTYLKFISEFKELS-
-SSLSPSFSHNALKNFLN-YQKKYTVYSQNICGLEKKAGIENLVHLHGDTENLKCMSCGRLHLFTHEHGKEIECIECKTRGYLHPNIVHYEEEHPNCAEL
IKVIKHLNLLIVIGTSLKPYGVKQVIKYFLSNNYISLYINKESPNLSSFFTHAWIGSVEDFFKILFDSLND--------
>tr|B8BR55|B8BR55_THAPS Uncharacterized protein OS=Thalassiosira pseudonana GN=THAPSDRAFT_20859 PE=4 SV=1
--------------------------------LARIILSNEPVVIITGAGLSAASGIRPYRGVNGLWSEV-IWKQSTREEFRKNPLQ---WYNSFWLYFP
PEFYEPNEGHEVIAKLASLPNTNVKVITQNMDGLHSMTRHSRLIEAHGRLGLYKCIGESDSTDRSDDISEPPLCPSCH--RPCPPQALQFDEGYYQFEKM
ERWIENASLVIFVGTSFAVSLTDRALEHARQEGKLVYNFNLDGGVLESNAWENVVGDVQRTLPELMRACEER-------
>tr|A0A0K3APA0|A0A0K3APA0_BABMI Uncharacterized protein OS=Babesia microti strain RI GN=BmR1_III04450 PE=4 SV=1
-------------------GPLDKCQIFDPKSQVQHLKTCNFAIVHSGAGVSTSSGISDFRGPCGIWTIEKKLQV-DSDCTLRDNSLVVQYGKVFQKAVD
IWLALPSKVHLIIAKLVTT-GHIKHIITQNVDSLHNCRGLSQISELHGNLFVEACEVCGRRYLRAFVIPSGHYCGLCSFVG-ICTDVVWFDSYDPLYYQA
IHYSKLADLHLCLGSSLAIQPACEYPSVERRPDSNLYIVNYQKTSLDDEATQVIHEDVNYVITQLVSN-----------
>tr|K7GXX1|K7GXX1_CAEJA Uncharacterized protein OS=Caenorhabditis japonica GN=WBGene00124448 PE=4 SV=1
-------------------------------------ATGKPVLVLVGAGVSTGSKLPDFRGKHGVWTLQKEGKEA-------DGV---D----------
FKLALPGVSHRSILALHKA-GYIKTIITQNVDGLDRKVGIKDLIEVHGNLFLEKCTTCQREYVREDIVMTGRKCEACR--GKLQDVTLDWDSAPKHLARI
RRAWKETSHLLCIGSSLEIIPMGSLPIDAMNKNIKTTTINYQETAHEKLVETAIHADVKLVLYSLCAALQ---------
>tr|A0A0R2AXK6|A0A0R2AXK6_9LACO Uncharacterized protein OS=Lactobacillus brantae DSM 23927 GN=FC34_GL001104 PE=4 SV=1
------------------------------NQLTELINSHHHIVALTGAGISTSAGINDLMHTS-----HATSAISSKANLKARPEE---FYQAMHKNLG
PFQNGPTIAHKALAKLEQT-GHLDAVVTTNVDYLHELAGNNKVADIWYSFNDNHCIENGHQYDINTLQGGVPYCPVDG--SLISPGPTYHGTSQNAIQNA
MQWMDQADMVLVIGSNGYY-------DRVN-TQVPLVQINPAATEFDRQATLNIHATADEVLKNF--------------
>tr|X6M8F1|X6M8F1_RETFI Transcriptional regulator, Sir2 family protein OS=Reticulomyxa filosa GN=RFI_27626 PE=4 SV=1
------------------------------TKLAEAIKNSKHFIAFTGAG-----GIQCVLEGAGVWTRQAADG--KG-----------ETYKKGKST-S
MFKAMPSKTHMALVALFEA-GYLKHLTSQNVDGLHRISGFDGLDELHGNCKLEVCSECRRQYLRDFEVETGRLCSSCK--GALKDTIIHFGETLPDINSA
FANANTADVCLAIGSSLTVTPAADVPKRVGKTSNTLCIVNLQKTPLDQYAKIRIYAKCDSVMELLMQKLE---------
>tr|A0A094F9J0|A0A094F9J0_9PEZI Uncharacterized protein OS=Pseudogymnoascus pannorum VKM F-103 GN=V499_00620 PE=4 SV=1
----------------------------------DAFRQRKRIVIIAGAGISASAGIATFQDLPV-----KGRDVFSMNSYNDDASTLNETMCRMYSSI-
-RSASPTQFHHVIEELAKE-GRLHRLYTQNIDGLDTQLPSPTTIQLHGDLRTVKCQGNPTHGSFNPELGALPCCAICKNIPLMRPRVWLYDDYDYADTSA
SDLRSKPDAVIVVGTSLKVESRRKFAIDMRKCGGLSAWINLKPPPQPKCFDMVVKGDSDIIA-----------------
>tr|A0A094HRM0|A0A094HRM0_9PEZI Uncharacterized protein OS=Pseudogymnoascus pannorum VKM F-4519 (FW-2642) GN=V501_02383 PE=4 SV=1
----------------------------------DVFRQKRKIVVIAGAGMSATAGIPTFEKLQVDGKNVKGKDVFSRNSYINDDRRLHKAICEMHQLI-
-MAANPTQFHLLIASLAEE-GRLHRLYTQNIDGLDTQLETPKTIQMHGNLRTVQCIGNATHTEFNPENGAEPWCSMCEEVYGTKPRVLLYDEPDFEDSIQ
HDLKAKPDAVIVVGTALKVMAAKSLVRDMQQARGYTAWINLRPPPNDKCFNIAIKGNCEDIA-----------------
>tr|E1ZSC1|E1ZSC1_CHLVA Putative uncharacterized protein OS=Chlorella variabilis GN=CHLNCDRAFT_141212 PE=4 SV=1
------------------------------ERLLEVAATSQRIVVFSGSGLSASSGMSTFSTRGGLYERYDGKMLFTYLFFDRQRPEAQAFFADIYSEAV
--RAEPAPGHHALRQLLDA-GRLHRHYTLNIDGLAEEVGMGVTVEMHGNVRHLVCPECYATQPMTAAIKEAVPCGDCGH-GAMRFKVMMYDDGPDVMELM
EEDVKAADLVLWVGISFQQSASTLYFRKVREGETVQALVNPSDEALFNQSVLEVLAEADEVLPLMADRLRQH-------
>tr|I0YJB6|I0YJB6_9CHLO DHS-like NAD/FAD-binding domain-containing protein OS=Coccomyxa subellipsoidea C-169 GN=COCSUDRAFT_60150 PE=4 SV=1
--------------------------------MLDAAASASSLLIFTGSGLSATSGMSTFSTKGGLYERFDGKKLFTYSFFEKQRLEAMAFYADIYAEAK
--RAKPSAGHRALAAIAAM-GKMQRHYTMNIDGLAESVGLGQTLEMHGNIHELVCPECGAVSEVTPQIKRALRCGQCGD-ADLRCRVMLYDDGPEVFDVL
EDDVAAVDMILWVGISFQQSASTAYFRRVRDQECKQVVVNLSEDCLWNTDVIEVLASSDEALPKLAARLAQT-------
>tr|M7WJZ6|M7WJZ6_RHOT1 NAD-dependent deacetylase HST3 OS=Rhodosporidium toruloides (strain NP11) GN=RHTO_02413 PE=4 SV=1
-------------------------------------DSSAQVVAAVGAGISTSAGIPDFRGSCGIYSSSSPTHLFSYSSL-VHPESRFRFMGDLRKAAR
KADEPPTAFHGLMKRLERS-DKLMRVWSQNVDGLERQAGLGKVVALHGSLDEVVCGVCRWREKWRKRHGKALPCPQCRGLSSLRPSILLYDDSTSSLSAA
SDLSAGPDCLIVAGTSLRIPGFRRIVKDVRKRKGVCVFVNGEKVEWDEVFDYHFLGSTDTF------------------
>tr|A0A093YKL0|A0A093YKL0_9PEZI Uncharacterized protein OS=Pseudogymnoascus pannorum VKM F-3557 GN=V490_00229 PE=4 SV=1
---------HRVRKRARKMRGSLQTIREPLDDLRELVRSSEKIVVISGAGISVSAGYPTFEDMRRSK-K----TSFNRSLYSTSDE-ITGFHSTVRGMLH
SDLTEPSPFHKVMDELART-RPHFRHYTQNIDCVERLLPDAKTIRLHGRVDQARCGICNWVCDYKPHLFDSLYCQRCLQIGRLRPNVLLYGEPHPILETA
RHDLRIPELVLIVGTKLSI-PGARFCHAARSVGGASFWISKEEPMWSSLCDYVLIGDCDK-------------------
>tr|A0A0R1JAS5|A0A0R1JAS5_9LACO Sir2 silent information regulator family NAD-dependent deacetylase OS=Lactobacillus tucceti DSM 20183 GN=FC72_GL001451 PE=4 SV=
------------------------------DQIKQILDSPTPILVTASNGFSIGEGINIFQKIGDLIPKYHFNSILSAISYPDNLLDAWQVWARLINYFV
-GSYHISSQMESLKQLLK--NKDYLIATSNGEYHFNLAGFNSVLATEGDWGTLQCFDHDDLVSSLPTLDLLPKCEICG--NVLLPHLPFNENYLKKFSTF
FNSAHQALTILELGVGQNH-PNLRKPIFDSAPQVNYIIINRDHIVVPSKKTIEFSENVEDVLQEIT-------------
>tr|J8TLH9|J8TLH9_9ENTR SIR2 family protein OS=Pectobacterium wasabiae CFBP 3304 GN=Y17_0061 PE=4 SV=1
------------------------------TSAAHSIQEADAIIIGASNGLSIAAGIHLFMDKGDFRLQHGFRNIIRGCFHSPRESEKWAFFSRVFDYFL
-HDRMPDPVIADLYNLVK--DKNYFVVTSNIDAHFPVGGFARVFEFEGNCRNLQCAACHDLYPGDEPVELIPECPKCG--GHMQVHIETSRLFLKHQKAF
SDFLEKKIVFLELGVGARN-QLIKAPFMSHEPHARYITFNVGELYIPDSKSIGLDGDIGYHLRQLV-------------
>tr|F4XC34|F4XC34_9FIRM Uncharacterized protein OS=Ruminococcaceae bacterium D16 GN=HMPREF0866_00945 PE=4 SV=2
------------------------------RPVAEKIQKADAILIGASNGLSITEGLHLFEDLGDFKDKYGLRCLLHGMGARPSEEVKWAFWSRLIHHYC
-GQYQPTQVMQDLKAIVG--SRDYFVLTSNGECHFEGSGFEKIYEIEGTWLTMQCARCHDLYPTLEPSDLVPRCPCCG--GPMEVHMAAGPNMVPARQRF
QRFLEKKLVVLELGIGWRN-QLIKAPLMRDEPNATYITINLGEVYIADHKSFGLDGALSDILSSLR-------------
>tr|D7GTI9|D7GTI9_9FIRM NAD-dependent protein deacetylases, SIR2 family OS=butyrate-producing bacterium SS3/4 GN=CK3_14220 PE=4 SV=1
------------------------------NPIAEKFREADAILIGASNGLSITEGLHLFERLGDFKRKYGLGCILQGMMAGPSEEEKWVFWARLIHHYC
-GQYRPTPVMNDLKAVVG--EKDYFVVTSNGEGHFELCGFDKIYEIEGNWFTMQCARCHDLYPSLEPTELVPRCPKCG--GPMDIHMGAGQRMIPAQARF
QNFLGKKLVVLELGIGWRN-QLIKAPMMRAEPNATYVTLNLGEIYITDEKSFGLDGRLDELLPALR-------------
>tr|A0A0M1NB20|A0A0M1NB20_9BACI Uncharacterized protein OS=Bacillus sp. FJAT-21352 GN=AM232_12650 PE=4 SV=1
------------------------------QEVLSKIKKADSIVIGASNGLAISEGINIFLEHGDFRKKYGFRNIVQGAFYSPSEEEKWAFFSRMYAYFL
-NNKEASPVMKNLYELVK--DKNYFVVTSNTDSHFTLTGFPRLFEIEGNSRYLQCSNCHNIYQGDEPSNLIPKCPECG--GPMQVHVEVDLNFLRSFQAY
QDFIGKKIVLLELGIGARN-QLIKAPFMNNEENATYITFNKGELYIPDDKSIGIDGDIAEVLQQLV-------------
>tr|A0A0J0H9G1|A0A0J0H9G1_ENTAS Uncharacterized protein OS=Enterobacter asburiae GN=ABF77_12880 PE=4 SV=1
------------------------------YHALTRIQEADAVIIGASNGFSIASGIHLFWHHGDFGKRHGFASIIQGCFHHTCEAEYWAFYSRLFDYFI
-NVRAPGEVMENLLALVN--HKKFFVLTSNIDGHFVKAGLEHLFEIEGSGLNLQCANCHDLYSGAEPDALIPCCPVCG--GKMRVHVEVDSGFLKSFRSY
RRFLESRTVFMELGVGARN-QLIKAPFMQYNPESSYITFNKGELFIPAARSVGIDGDIGHNLAMLA-------------
>tr|C6JES6|C6JES6_9FIRM Uncharacterized protein OS=Ruminococcus sp. 5_1_39BFAA GN=RSAG_02443 PE=4 SV=2
------------------------------QEISQIIKEADGILIGASNGLSIAEGYNIFQENGDFREKYGLRCVLHGFSVPK-VEERWAFVSRLVKAKA
-MQDEPSEIMKNIYALVK--DKEYFVVTSNAEDHFVPAGFERVFEMEGKLTQMRCKNCHDVYPNQKPKELLPKCPKCG--GDMEVNWGEMSSFTEKAARY
QEFIGKKLVILEFGIGWRN-QMIKAPLMQAEPQARYITFNKGEIYIPEEKSIGVDGNLTVALKEIR-------------
>tr|D4LRG3|D4LRG3_9FIRM Uncharacterized protein OS=Blautia obeum A2-162 GN=CK5_19910 PE=4 SV=1
------------------------------RNIYKAIQEADALLIGASNGLSISEGYNIFQKDGDFRSRYGIRNILQGLFFQPTEESKWAFFSRLISRKC
-YLEQPGPVMEDLYRLVG--SKDYFIVTSNGEDHFVPAGFDKVFEMEGRLTQSRCQNCGTPYENQNPSELVPCCSCCG--GPVTVNMANSNAFFQKMQDY
QNFIGKRLAILELGVGWRN-RMIKEPFMSAEPEAVYITFNKGEVYIPSGKSIGVDGDIGEALKEIC-------------
>tr|T5LA38|T5LA38_STEMA Uncharacterized protein OS=Stenotrophomonas maltophilia MF89 GN=L681_00925 PE=4 SV=1
------------------------------RAALERIQAADAVVIGASNGLSISEGIHIFAAHSEFRRQHGFHCIIQGCFHPPSEAQEWAFFSRMHAYFT
-RDKAPGEVMRNLRDLVQ--NKQHFVVTSNIDAHFRLAGFDHLFEIEGNCQQLQCANCHDLYLGVESEHLIPKCPQCG--GPMQVHIEVDRMFLKRRRAF
SEFLGKRIVFIELGVGARN-QLIKAPLMREEPQASYLCFNRGEVYIPGGKSIGIDGDIAQALRRLA-------------
>tr|F7SFE0|F7SFE0_LACJH Uncharacterized protein OS=Lactobacillus johnsonii pf01 GN=PF01_01267 PE=4 SV=1
------------------------------EEIKKWLADADAVIVTAGNGFAQMEGLDMFPIEKNIREKYHVKTIADALDKDDSWDEKWQFWSQLINEYS
-VEYEPSKAMKQLKELLD--GKNYFIATSTFGHFFEKAGFDKIFNVFGDWTMMQCSSLNHTRSDLS-QGEVPKCEDCN--SPMELHMPLNTHFFPANTRF
RWFLTNKVVVLELGVDPTS-PQLLDPMAKEFKDWHYVAADLSQDELPDKRSVGLEMALPEAIEKIS-------------
>tr|I7IVH7|I7IVH7_9LACO Uncharacterized protein OS=Lactobacillus hominis DSM 23910 = CRBIP 24.179 GN=BN55_08130 PE=4 SV=1
------------------------------EQAKTWLKDADNIIVTAGNGFSIMEGLDMFDVESKTAKKYHVHTIADALDKKDSWDEQWKFWSELIQEYS
-LDYEPSKTMKELRALLD--GKDYFIATSSYGHFFEKAGFERIFDVFGDWTQMQCSSLNHVRSDVE-QGSVPKCEDCN--SPMELHMPLNAHFYPANTRF
RWFLDKKVVVLELGVDPTS-PQLLDPMISSHPTWRYIAADLSQDDLPDKTAIGLNTSISNVIKDLK-------------
>tr|D6S2L8|D6S2L8_9LACO Uncharacterized protein OS=Lactobacillus jensenii JV-V16 GN=HMPREF0526_10551 PE=4 SV=1
------------------------------EKARKIINEADAILITAGNGFASLDGFDMFKIQPDLVEKYNFKTIGDALDRRSNWDEQWSIWRRFIDNYS
-INYQASSMMQNLKTLLK--GKEYFIATSYYIHAFENAGFDKIFNIFGDWTTMACSSINHLKSDLQ--YGVPKCEICN--SEMEIHMPLTAHFYPANTRL
RIFISKKVAVLGLGVDELS-PQLLEPITHSFESWHYISADLCITDLPQKRSIAAESNSESLLEGLI-------------
>tr|A0A0R1S9C6|A0A0R1S9C6_9LACO Uncharacterized protein OS=Lactobacillus psittaci DSM 15354 GN=FC23_GL000957 PE=4 SV=1
------------------------------EKAKKLINDADCILVTAGNKFAIADGLDMFKVQPDLVEKYDVHTIGDALDKKPSWPEQWAMWRRFIDDYS
-VNYQPSDAMLQLKQLLT--GKDYFIATSYFTHAFENAGFDKIFNIFGDWTTMACSSVNHLKSDLA--QGVPKCEICN--SEMEIHMPLTEHFYPANTRM
RIFIDKKMLVLELGVDETS-PQLLDPIAHMFDSWKYIAADLASDELPEEKALAFNTNVANFLKELS-------------
>tr|D0DPK4|D0DPK4_9LACO Uncharacterized protein OS=Lactobacillus jensenii SJ-7A-US GN=HMPREF0527_01223 PE=4 SV=1
------------------------------EKAKKLIDDADCILVTAGNKFAIADGFDMFKVQPDLVEKYDVHTIGDALDKKPSWPEQWTMWRRFIDDYS
-VNYQPSDAMLELKQLLT--GKDYFIATSYFTHAFENAGFDKIFNIFGDWTTMACSSVNHLKSDLA--QGVPKCEICN--SEMEIHMPLTAHFYPANTRM
RIFIDKKMVVLGLGVDELS-PQLLDPILHSFENWHYISADLDSSDLPQKRSIGTGSNSKSLLEGLI-------------
>tr|A0A0R2KRV5|A0A0R2KRV5_LACAM Uncharacterized protein OS=Lactobacillus amylovorus DSM 16698 GN=IV44_GL000122 PE=4 SV=1
------------------------------TKVKEWLKDADAVIVTAGNGMAKEEGLDIFDDEGKVADKYDVHTIGDALDKKDTWDEQWAFWSQLVNEYS
-LEYEPSETMLALKELLK--DKQYFIATSTFGHFFENAGFNRIFNAFGDWTRMQCSSVNHQKDDRE-KGEVPKCEDCN--SPMELHMPLNANFFPANTRF
RWFLDKKVVVLELGVDETS-PQLLDPMVKEFPNWHYVAADLADNDLPDKRSAGFATDSHDMMMKLT-------------
>tr|A0A0R1UIA3|A0A0R1UIA3_9LACO Uncharacterized protein OS=Lactobacillus kalixensis DSM 16043 GN=FC46_GL000171 PE=4 SV=1
------------------------------STAKKWFKDSDAVIVTAGNGLSQEEGLDIFDNRGEIAEKYDVHTIGDALDKKDSWDEQWQFWSKLINDYS
-LNYEISPSMKRLKQLLE--GKEYFIATSTFAHFFENADFNRIFDVFGDWTKIQCSSINHQKDDRE-KGEVPKCDVCN--SPMELHMPLNAHFFPANTRL
RWFLDKKVTVLELGVDETS-PQLLDPMVDKFPSWHYVAADLDEEDLPDKQSLACSSNIHDFLKELV-------------
>tr|A0A0R1PEC7|A0A0R1PEC7_9LACO Uncharacterized protein OS=Lactobacillus kefiranofaciens subsp. kefirgranum DSM 10550 = JCM 8572 GN=FC94_GL000192 PE=4 SV=1
------------------------------TQVKEWIKNADAVIVTAGNGFAQTEGLDIFDDQGKVADKYDVHTIGDALDKKASWDEQWDFWSQLINEYS
-LEYEPGETMLALKKLLQ--GKEYFIATSTFAHFFENAGLNRIFNAFGDWTEMQCSSINHKFSDIE-KGEVPKCEDCN--SPMELHMPLNAHFFPANARF
RWFLDKNVVVLELGVDETS-PQLLDPMVKEFANWHYVAADLADEDMPDKCSAGFATNSHDVLMNLT-------------
>tr|Q5FIL3|Q5FIL3_LACAC Putative uncharacterized protein OS=Lactobacillus acidophilus (strain ATCC 700396 / NCK56 / N2 / NCFM) GN=LBA1649 PE=4 SV=1
------------------------------TKANEWLKDADAVIVTAGNGMAKEEGLDIFDNQGEIAEKYDVHTIGDALDKEDSWEEKWTFWSKLINEYS
-LQYEKSENMKALEKLLE--DKEYFIATSTFAHFFENAGFNRIFDAFGDWTKMQCSSINHQKDNRE-KGELPKCEDCG--SPMELHMPLNAHFFPANTRF
RWFLEKNVVVLELGVDATS-PQLLDPMVNQFSNWHYIAADLANDNLPDKRAIGFGSDTHETLMNLT-------------
>tr|I7LFQ8|I7LFQ8_9LACO Uncharacterized protein OS=Lactobacillus gigeriorum DSM 23908 = CRBIP 24.85 GN=BN52_09220 PE=4 SV=1
------------------------------EQAKNWLKAADAIIVTAGNRYANYEGLDIFTQEPKWAKKTKANNIGNALEAPLSWEDKWAFWSDLIQRYT
-LSYQPSHQMEQLQAVLA--DKPYFIANSSFAHLFEQAGFARIFNIFGDWTKTQCSSINHNTDDLE-NGKVPKCTVCG--KELELHMPLNSNFFPANHDF
RWFIKVNLVVLQLGVDVLS-PQLVAPVINQFSTWHFISCDLEASALPDKRSYSEASDPKELLAKLV-------------
>tr|I7JWZ8|I7JWZ8_9LACO Uncharacterized protein OS=Lactobacillus pasteurii DSM 23907 = CRBIP 24.76 GN=BN53_08675 PE=4 SV=1
------------------------------QEAKTWLKDADAVIVTAGNRMAINEGLDIFMQEPDWAEKTEANNIANALDVPSSWQEKWQLWSDLIDRYT
-VNYQASEQMKQLKSLLA--DKPYFIASSSFAHLFEKAGFDKIFNIFGDWTKTQCSSINHHTDDLA-SGQVPVCKTCG--KELELHMPMTPHFYPANHDF
RWFIDAKLVVLQLGVDLSS-PQLAAPVIEGFPNWRFISCDLPNGSLPYDRVYTESSDPKTLLAKLM-------------
>tr|A0A0R2DL39|A0A0R2DL39_9LACO Uncharacterized protein OS=Lactobacillus taiwanensis DSM 21401 GN=FD18_GL001789 PE=4 SV=1
------------------------------EEIKKWLAEADAVIVTAGNGFAQMEGLDMFPIEKKISEKYHVKTIADALDKNDSWDEKWQFWSQLINEYS
-VEYEPSKSMKELKILLT--DKNYFIATSTFGHFFEKAGFDKIFDVFGDWTRMQCSSLNHTYSDLS-QGEIPRCEDCD--SPMEIHMPLNAHFFPANTRF
RWFLTKKVVVLELGVDPTS-PQLLDPMVKEFKDWHYIAADLSQDDLPDKRSAGLGMALPEVIEKIS-------------
>tr|A0A0R1PQT7|A0A0R1PQT7_LACHE Uncharacterized protein OS=Lactobacillus helveticus DSM 20075 = CGMCC 1.1877 GN=FC11_GL000263 PE=4 SV=1
------------------------------TKVKEWIKDADAVIVTAGNGMAKEEGLDIFDDQGKIADKYDVHTIGDALDKKDSWSEQWSFWSELVNEYS
-LQYEPCETMQALKQILQ--DKDYFIATSTFAHFFENAGFKRIFDAFGDWTKMQCSSINHQKDDRETEDLVPKCEDCN--SPMELHMPLNANFFPANTRF
RWFLDKKVVVLELGVDETS-PQLLDPMVKEFPNWKYVAADLADEDMPDKRAAGFATNSHDVLMNLT-------------
>tr|N2AKX2|N2AKX2_9LACO Uncharacterized protein OS=Lactobacillus sp. ASF360 GN=C821_00598 PE=4 SV=1
------------------------------EQAKKWLSDADAVIVTAGNRFAQEEGLDIFDNKGEIAEKYDVHTIGDALDKKDSWGEQWAFWSELINQYT
-LNYVPSENMGNLKKLLD--DKQYFIATSTFAHYFENSGFNRIFNVFGDWTTMQCSSVNHQKSDIELESLVPKCEICN--SEMEIHMPLNAHFFPANARL
RWFLDKKVVVLELGVDETS-PQLLDPMISDFPNWHYITVDLKKEDLPGKKSAVLNSDVHNLLKQLT-------------
>tr|D5GZB4|D5GZB4_LACCS NAD-dependent protein deacetylase, SIR2 family OS=Lactobacillus crispatus (strain ST1) GN=LCRIS_01676 PE=4 SV=1
------------------------------VTAKKWLKNANTVIVTAGNGMAKEEELDIFDDQGKIADKYDVHTIGDALDKRDTWSEQWAFWSELINEYS
-LQYEPSETMLALKKLIR--DKKYFIATSTFGHFFENAGFNRIFNAFGDWTKMQCSSINHQKDNRETADLVPKCEDCN--SPMELHMPLNANFFPANTRF
RWFLDKNVVILELGVDETS-PQLLDPMVKQFPNWHYIAADLADADLPAKRAMGFDSNSHEMLMNLI-------------
>tr|C2EPT4|C2EPT4_9LACO Sir2 family NAD-dependent protein deacetylase OS=Lactobacillus ultunensis DSM 16047 GN=FC57_GL001573 PE=4 SV=1
------------------------------TKVKEWLDKADAVIVTAGNGMAKEEGLDIFDDQGKIADKYDVHTIGDALDKKDTWSEQWSFWSELVNEYS
-LEYEPSETMLALKKLLK--DKQYFIATSTFGHFFENAGFNRIFNAFGDWTRMQCSSINHQKDDRPSDDLVPKCEDCD--SPMELHMPLNANFFPANTRF
RWFLDKNVVVLELGVDETS-PQLLDPMVKEFANWHYVAADLADEDMPDKRAVGFATDSHNMLMSLA-------------
>tr|A0A0R1YNP8|A0A0R1YNP8_9LACO Uncharacterized protein OS=Lactobacillus hamsteri DSM 5661 = JCM 6256 GN=FC39_GL000063 PE=4 SV=1
------------------------------TDAKKWLKDADAVIVTAGNGMAREEGLDIFDDQGKIADKYDVHTIGDALGKKDSWAEQWAFWSQLINEYS
-LEYEPSETMLALKALLK--DKQYFVATSTFGHFFEGAGFNRIFNAFGDWTKMQCSSINHQKDDRETEEMVPKCNVCN--SEMELHMPLNAHFFPANTRF
RWFLDKNVVVLELGVDETS-PQLLDPMVKEFPNWKYIAADLEEDDMPDKRSYASDSNSHKLMEELS-------------
>tr|A0A0D6A4S7|A0A0D6A4S7_9LACO Uncharacterized protein OS=Lactobacillus acetotolerans GN=LBAT_1377 PE=4 SV=1
------------------------------DQAKKLIASADAVIVTAGNGMAKEEGLDIFDDEGAIAEKYDVHTIGDALDKKASWAEQWEFWSKLIAEYS
-LNYEPSTTMLNLKTLLK--NKKYFIATSTFGHFFESAGFNRIFNAFGDWTKMQCSSINHYKDDRETEEMVPRCEVCN--SEMELHMPLNANFFPANTRF
RWFLDKKVVVLELGVDLTS-PQLLDPIVHEFPNWNYIAADLSQKDLPAKKSLAFNADPHTLLTGLT-------------
>tr|D4YTM3|D4YTM3_9LACO Uncharacterized protein OS=Lactobacillus amylolyticus DSM 11664 GN=FD39_GL000441 PE=4 SV=1
------------------------------TKAKKWLNDADAVIVTAGNGMAREEGLDIFDDLGDVAEKYDVHTIGDALDKKASWTEQWTFWSQLINNYS
-LNYEPSESMLALKKLLK--GKEYFIATSTFAHFFENAGFNRIFNAFGDWTKMQCSSINHLKDDRETEDLVPKCEVCN--SEMELHMPLNAHFYPANARM
RWFLDKKVAILELGVDETS-PQLLDPMVKEFGDWHYLAADLRQDDLPDKRSLAFDSNSYDLLMNLA-------------
>tr|A0A0F4LV94|A0A0F4LV94_9LACO Uncharacterized protein OS=Lactobacillus apis GN=JF72_02080 PE=4 SV=1
------------------------------NKAQQLLNEADVVIVTAGNKMAKNEGLDLFEQDPEVASKYHVNSIGDALDHKDSWAEQWLFWSQLIEKYS
-LNYVPSPAMKKLRELIG--EKKFFIATSTFGHFFEQADFNRIFNAFGDWTVMQCSSVNHAKSDQEITKLVPKCEQCG--QPMEIHMPLNEHFYPANTRF
RWFLEEKVVFLELGVDETS-PQLFEPIIRQFPQWTYVAADYQQEMLPLDKSAAVNADAASLLQALV-------------
>tr|A0A0F4LG83|A0A0F4LG83_9LACO Uncharacterized protein OS=Lactobacillus melliventris GN=JF74_03650 PE=4 SV=1
------------------------------NKAKQLVQEAEAVVVVAGNGLAKVEGLDLFERDPSIVQKYDVHSVGYALDQHPSWSEKWQLWSSLIQKYS
-FDYRPSSTLKNLLQLIS--HRQYFVATSAFGHFFETAGFNRIFNAFGDWTKAQCASINHLSNIQTLAKLVPKCEVCG--QPLEIHLPLNDHFYPANSRF
RWFLEKKTVFLELGVDETS-PQLREPIEHAYPQWSYVAADYPQETLLPERSAGTNADTVSLINNLV-------------
>tr|A0A0F4LM93|A0A0F4LM93_9LACO Uncharacterized protein OS=Lactobacillus kullabergensis GN=JF76_03420 PE=4 SV=1
------------------------------NKARQLVQNADTVIVVAGNGLAKTEGLDLFEQSPGVVQKYDVHSVGFALDQHSSWSEKWQLWSNLIQKYS
-VDYHPSKTLQKLKQLID--NKQYFIATSAFGHFFETAGFNRIFNVFGDWTKAQCSSINHLKDCQSIEELVPKCDVCG--QPLEIHMPLNEHFYPANTRF
RWFLDKDTVFLELGVDETS-PQLREPIEHAFPQWSYVAADFKQKNLLPERSAGTNADAASLINNLV-------------
>tr|A0A089ZKD3|A0A089ZKD3_9LACO Uncharacterized protein OS=Lactobacillus sp. wkB8 GN=LACWKB8_0365 PE=4 SV=1
------------------------------DKAQYLVQNADTVVVVAGNGLAKAEGLDLFERAPDIVQKYDVHSVGYALDQHSSWSEKWQLWSSLIQKYS
-LAYRPSETLKQLKQLIG--NRQYFIATSTFGHFFETAGFNRIFNAFGDWTKMQCSSINHLQDSHNLEHLVPKCEVCG--QPLEIHMPLNDHFYPANSRF
RWFLDKNTVFLELGVDETS-PQLREPIEHAYPQWSYVAADFPQETLLPERSAGVNGDTASLINYLV-------------
>tr|A0A0R1U091|A0A0R1U091_9LACO Sir2 silent information regulator family NAD-dependent deacetylase OS=Lactobacillus equi DSM 15833 = JCM 10991 GN=FC36_GL000012
------------------------------KLARKWIKQADAVLVTASNGFAISEGVNLFRQAGNMVTKYRLPNLLSAFSYDPHDVERFRMYGRVAEFYN
-YSYHASPVMQKLQGLLA--GKDYLVWTSNTEGHFKQAGLP-VLEVEGSWLEGICQNDHV--DLKNTVADVPLCDICG--GTVKLNLAGPDF---QVDAF
QNFINRKLLVLELGIGAHN-QLIKAPSMQANHNSRYITINKGELNIPAARAIGFDADLSLALEELL-------------
>tr|A0A0K2LCE4|A0A0K2LCE4_9LACO Uncharacterized protein OS=Lactobacillus heilongjiangensis GN=JP39_06140 PE=4 SV=1
------------------------------NQAKQILNSAPHVLVTASNGFSIGEGINIFQKVGDLIPKYHFNSILSALSYPDNLLDAWQVWARLINYFV
-GNYHISPQMQSLKQLLK--SKDYLIATSNGEYHFNLAGFNSVLATEGDWGTVQCFGHDNEIKSLPTFDSLPKCETCG--NILLPNLPFNAKYLKKFSAF
LNSTHNPLTVLELGVGQNH-PNLRKPIFDAAPQANYIIINRDHIVIPDKQTIEFSGNIEDVLRDLT-------------
>tr|A0A088RD95|A0A088RD95_9SPIO Sir2 silent information regulator family NAD-dependent deacetylase OS=Treponema putidum GN=JO40_05735 PE=4 SV=1
------------------------------EKLKQILSEAKTVVIGAGSGLSTSAGFT-FEKYSDFAAKYGFHDMYSGGFTPESLEERWAYWSRYIMINR
-YMNPPKPVYEDLFSLVK--DKDYFVLTTNVDHCFQKAGFDRLFYTQGDYGLFQCSECHETYDNEKPAELVPHCPVCG--KPMSMNLRADITFVTASKRY
ENFLSGKVLFLELGVGGNT-PGIKYPFWQLNLNADYACINFGEAVVPLNQSICINEDIGEVLKEIK-------------
>tr|J0SXF4|J0SXF4_9ACTO Uncharacterized protein OS=Actinomyces sp. ICM47 GN=HMPREF1136_0726 PE=4 SV=1
------------------------------TTLREAIEAADSILIGAGAGLSAADGDH-FDARADFRDQRGITDAYSGGFYPPTSEERWAFWSRMISLLR
-YEAGPGQVYADLLGLVS--ERDYFIITTNVDHRFQTSGFDHLFYTQGDYGLLQCSVCHDTYDNEKPSELIPQCPRCG--EEMTTNLRVDARFVQAAGRY
EDFLVDRVLYLELGVGMNT-PSIKFPFWRYNPEATYACVAL-DASAPADRSLLIRGDIAEALASAR-------------
>tr|A0A0A0WXF6|A0A0A0WXF6_9SPIO Sir2 silent information regulator family NAD-dependent deacetylase OS=Treponema sp. OMZ 838 GN=JO41_01095 PE=4 SV=1
------------------------------EQLKQIISEAETVVIGAGSGLSTSAGFT-FKKYSDFAVKYGFQDMYSGGFTPASLEERWAYWSRYIMINR
-YMDPPKPVYDNLLSLVR--NKDYFVLTTNVDHCFQKAGFDRLFYTQGDYGLFQCSECHHTYDNEKPSELVPHCPVCG--KPMSMNLRADDTFVTAANRY
QTFLPGDVLFLELGVGRNT-PGIKYPFWQANPNAQYVCINFGEAFAPYKRSLCINDDIGAVLQELL-------------
>tr|A0A087BL08|A0A087BL08_9BIFI SIR2 family protein OS=Bifidobacterium merycicum GN=BMERY_1238 PE=4 SV=1
------------------------------DLLKTAWHEADAVIIGAGSGLSTAAGFT-FERYSDFAATYGIRDMYSGGFYPASLEEYWAYWSRFITVNR
-YHDVPKPVYADLLKLVA--GKDYFVITTNVDHCFQKAGFARLFYTQGDYSLFQCSVCRQTFDNEAPTELVPSCPYCG--RPMTMNLRCDDTFVEAAERY
DDFLERKVLFLELGVGGNT-PVIKYPFWQASTDAVYACSNLGEANCPARQSICINADIGDVLARLR-------------
>tr|A0A0E2E3K2|A0A0E2E3K2_TREDN Uncharacterized protein OS=Treponema denticola H-22 GN=HMPREF9726_02091 PE=4 SV=1
------------------------------EKLKQVLSEAETIVIGAGSGLSTSAGFT-FEKYSDFAVKYGFHDMYSGGFTPESLEEHWAYWSRYIMINR
-YMDPPKPVYKDLFSLVK--DKDYFVITTNVDHCFQKAGFDRLFYTQGDYGLFQCSECHETYDNENPTELVPRCPVCG--KPMRMNLRADHTFVTASKQY
EKFLSGKVLFLELGVGGNT-PGIKYPFWQENPNARYACINFGEAVVPPKQSICINDDIGEVLKKMV-------------
>tr|A0A0A0DEG5|A0A0A0DEG5_9STRE NAD-dependent protein deacetylase of SIR2 family OS=Streptococcus sinensis GN=SSIN_1787 PE=4 SV=1
------------------------------KEAKKLLDEADAVLIGAAAGLSTAAGLD-FQQHSDYIEKYGMTDMYSAGFYPQTLEEKWAYWSRHVLLNR
-YG-ESLPLYQDLYNLVK--DKEYFVMTTNVDGQFEKAGFDRLFEIQGNYGEFQCSVCHQVYSNEEPSELIPYCPRCQ--APMNMHLRIDSTFVEEQEAL
QKFVDKKLVLLELGVGYNT-PTIKYPFERIFPNVNLIRLNIEDKPKKG---ITINQDIK---EVLA-------------
>tr|Q98QC4|Q98QC4_MYCPU Uncharacterized protein OS=Mycoplasma pulmonis (strain UAB CTIP) GN=MYPU_4420 PE=4 SV=1
------------------------------EIFLQAIEQAELLVLGIGAGLPGSVGFG-FEKNGDFIKEYKLVDMLQASLFEPNWPSYWAFQSRFTSINY
-YDQPVSESFLKLKELIK--DKNYFIITTNSDSCLEKANFDKIFYIQGKYKHFQCSKCHNLYEDKEPYELIPRCPKCD--SFLEINKRIYKGMVEQKAKY
EAFVDKKTLFLELGVGYTT-PQIKIPFQKQNPQSFYLSISNKTYRLNPKQALLLEVDLKDFFEKF--------------
>tr|U4S7U0|U4S7U0_HAEPR Sir2 family protein OS=Haemophilus parasuis 12939 GN=HPS12939_0647 PE=4 SV=1
------------------------------QQAKQRIEQADFMVIGVSAGFFAAAGLT-FTQRQPFIQRYGMKDMYSAGFYPETEEEKWAYWAEHIWVNR
-FEPSALPLYQQLFALMK--DKNYFVITTNVDSQFAKAGFDKLFEVQGNYGELQCAKCHSVYDNETPTALVPKCPVCG--GKMEIHLRVDHRFVEAQQRY
ATFAQGNTVYLELGIGFNT-PTIRYPFEQYNPQATLIRLNRDHPEGFAEFLALQDTAKKLPNSHRT-------------
>tr|J6HTL5|J6HTL5_9FLAO Uncharacterized protein OS=Capnocytophaga sp. CM59 GN=HMPREF1154_1054 PE=4 SV=1
---------------------------------------MKNIIIGAGAGLSAAGGLDYFTAQFPHFAKRGYKNIMQILGSYHNALEYYAVWARHIHNIR
-YIPKATDPYLWLKEQVK--DKDYFVITTNVDHQFHKAGFDRIFAMQGDYGLFQCATCSDLYDNKERPEDIPHCPHCG--NYLVPNLRMDSSFVENAAAY
KAFLSEPVLLLEYGVGFNT-PTIRYPFEQRFPDVTLIRINTHNPEVPNCFSIGSD--QLSVVNSQW-------------
>tr|A0A0Q4QW02|A0A0Q4QW02_9BACL Sir2 silent information regulator family NAD-dependent deacetylase OS=Paenibacillus sp. Leaf72 GN=ASF12_17000 PE=4 SV=1
-----------------------------------RLDKADTILLGGGAGLSAAAGIA-FTDHGPFIEKYGFTDLYTSSFYPATEEEKWAYWAKHISLSR
-YEAGATKLYQDLFRLVQ--NKPYFVITTNVESQFEKGGFPRVFEIQGNYSYLQCAKCHNLYYNEQPAELVSKCPICG--GKMDPNLRMNRYFVQRDTSY
KNFLEKKIVFLELGVGFNT-PGIRYPFETYNEKAILIRLNKDHPEGMQAKTVSFTEDMQEVVLAVT-------------
>tr|A0A0A3APG7|A0A0A3APG7_9PAST Sir2 silent information regulator family NAD-dependent deacetylase OS=Chelonobacter oris GN=OA57_10310 PE=4 SV=1
------------------------------HQAKQRISQADFILVGAGAGFSTAAGLT-FEENQPFIRHYGMRDMYSAGFYPDCEEEKWAYWAQHILINR
-FEPPALPLYRQLLELVK--TKNYFVLTTNVDAQFEKAGFARLFATQGDYGYLQCATCHDLYSNAEPIALVPQCPICS--GKMVMHLRIDQHFIEAQKRY
TQFAQGSAVYLELGVGYNT-PTIRYPFEQFNRDAVLIRLNRDEPAGYDAQTICFTEDPNLVMAQLL-------------
>tr|R6HSU7|R6HSU7_9FIRM Uncharacterized protein OS=Firmicutes bacterium CAG:582 GN=BN721_00092 PE=4 SV=1
------------------------------LKIKDLIRNADAIVIGAGAGLSASAGID-FKKNPELVKAYGMTDMYTSSFYEDTEEERWSYWAKHINYSF
-IAPPPLRAYKELLEIVK--DKNYFVITTNVDGQFENSGFEKVFEVQGSYGKMQCSKCHNLYDDTEDSNLIPICPVCG--EKMEINIRKDAFFDELSDNY
ENFINKKLILIELGVGFNT-PGIRFPFEKYHDNITLIRINDKYNDMVHNRAICVKDDCANAITNIL-------------
>tr|C6AKJ2|C6AKJ2_AGGAN Sir2 silent information regulator family NAD-dependent deacetylase OS=Aggregatibacter aphrophilus (strain NJ8700) GN=NJ8700_097
------------------------------KVVKSALETADVVLIGAGAGFSAAAGLT-FTDNQPFIKKYGMTDMYSAAFYPTKPEQKWAYWAKHVWHNR
-WQPDTLPLYRELFDLVK--DKNYFVLTTNVDAQFEKAGFDRLFAMQGDYGKLQCKNCHDLYSNESPTALVPHCPKCG--GEMTMHLRVDGNFVEVQARY
AKFAHGKSVYLELGVGFNT-PAIRYPFEQYNPNALLVRLNRDYPEGFADKTVAFAEDPNKVLHALL-------------
>tr|A0A0Q7TBB4|A0A0Q7TBB4_9BACL Sir2 silent information regulator family NAD-dependent deacetylase OS=Paenibacillus sp. Root52 GN=ASD24_04090 PE=4 SV=1
------------------------------DRAKAIIQEADYILLGGGAGLSAAAGIT-FTDHGDFIDKYGFTDLYSSGFYPETQEDKWAYWARHIQLNR
-YDTGTTQLYLDLYELVK--NKKHFVISTNVESQFEKAGFASIFEIQGNYGYLQCEKCHDLYDNEEPTNLVPKCPVCG--GTMDVNLRINEYFVQSERMY
RSFLNQNVVYMELGVGFNT-PGIRYPFERYNEHATLLRFNQDEPAGLAHKTIAFTEDMNQAFQLIR-------------
>tr|A0A089LNV0|A0A089LNV0_9BACL Sir2 silent information regulator family NAD-dependent deacetylase OS=Paenibacillus borealis GN=PBOR_30905 PE=4 SV=1
------------------------------ERAKRALEGAEYVLLGGGAGLSAAAGIT-FTEHEPFINKYGFTDLYTSSFYPKTEEENWAYWAKHISVNR
-FEIGATSLYEDLFQLVK--EKEYFVISTNVESQFVKAGFPKVFEIQGDYSYLQCEKCHDLYYNESPTELVPKCPVCG--GKMDVNLRKNGYFVQADRRY
TQFLKGRIVYAELGVGFNT-PGIRYPFERYNDNAALIRFNLEHPEGAPFKTIAFTEDMREIVRDLM-------------
>tr|R9T6L6|R9T6L6_9EURY Uncharacterized protein OS=Candidatus Methanomassiliicoccus intestinalis Issoire-Mx1 GN=MMINT_12880 PE=4 SV=1
------------------------------KRLRCEIEETDAIVIGGGSGLSTSAGLT-FEENSDFITRYDLTNMYTGGFYPQTAEEYWAYWSRYIYVNR
-YNKTTGQPYLDLLKIVK--NKDYFVITTNVDHQFQIAGFDRIFCTQGDYGLWQCSKCHQTYDNEMPSELIPHCPICG--RKMCVNLRIDNNFVEAAENY
SMYINSRILFLELGVGCNT-PAIKYPFWRYNPQAVYACINLGEAHTAKPRSICIDEDIGKVLR----------------
>tr|A0A087AH13|A0A087AH13_9BIFI SIR2 family protein OS=Bifidobacterium choerinum GN=BCHO_0143 PE=4 SV=1
------------------------------ERARDVLAGARRVLIGAGSGLSTAAGLCYFRRHASFIERYGITDMYSAAFYPKDEADKWAYWAHHASVNN
-LEQPALPLYEELYDWAK--ERDYFVMTTNADSQFAKAGFDRIFTPQGDYAHIQCARCDGVYDAREDPSLIPHCPTCG--GPMAMHLRMDESFVQQQRRY
VDFVEQPTVLLELGVGWNT-PTIRLPFERQ-TGMPLVRMNRDDTAIDPTNGIALEGDIAQLLPAVL-------------
>tr|R6L8B4|R6L8B4_9FIRM NAD-dependent protein deacetylase OS=Blautia sp. CAG:237 GN=BN552_00668 PE=4 SV=1
------------------------------GRLRTALEEADAVVIGAGAGLSTSAGFT-FRAHSDFAAKYDFSDMYSGGFYPETLEEYWAYWSRYIYINR
-YMDAPKPVYEKLLELVR--DKDYFVLTTNVDHCFQKAGFDRLFYTQGDYGLFQCSECCQTYDNEEPTELVPHCPYCG--KPMTMNLRADNTFVQAAERY
SNFLGLKTLYLELGVGYNT-PGIKYSFWQLNHQNTYACLNYGQAECPNSQAICINSDIGEVLERI--------------
>tr|R5LPC3|R5LPC3_9SPIR Uncharacterized protein OS=Brachyspira sp. CAG:700 GN=BN758_00931 PE=4 SV=1
------------------------------QKLKEEIENSEYILIGAGAGLSTSAGFL-FEDNKDYIKKYGFTDMYSAGFYNPTLEEYWAYFSLNVYINR
-YDIEENETYLNLYNIVK--NKNYFVITTNVDGRFADSKFDKIFAVQGDFSLFQCSKCRQTFYNEKPTELIPKCPYCG--RNMSMNLRVDSTFVQQKSKY
ENFLNSKILFLELGVGFNT-PSIKYNFWRLNKKSVYASINLGECYSASERSICIDADIFEVLKKLI-------------
>tr|A0A0H0UDT6|A0A0H0UDT6_BRAHO Sir2 silent information regulator family NAD-dependent deacetylase OS=Brachyspira hyodysenteriae GN=SR30_04905 PE=4 SV=1
------------------------------EKLKSAIEKSDYILIGAGAGLSSSAGFL-FDDNKEYKEKYGLTDMYSAGFYNPSLEEFWGYFSLFVYINR
-YDLKADETHLNLLNIVK--NKNYFVITTNVDGRFEEANFDRLFKVQGDYSLFQCSVCKQTFYNEKPSELIPKCPHCG--ANMSMNLRSDNTFVQAKDKY
KSFLNKNILFLELGVGFNT-PGIKYSFWELNKNSIYASINLNNCLAISNRSICIDDDISKVLKYIK-------------
>tr|I7AVD8|I7AVD8_9BACT NAD-dependent protein deacetylase OS=uncultured bacterium scaffold00090 PE=4 SV=1
------------------------------SKLKKTLETSDAVVIGAGAGLSTSAGFV-FKRYSDFEKKYGFHDMYTGGFHPQTPEEHWAYWSRYIYVNR
-YMDAPKPVYNALFDLVK--DKDYFVITTNVDHCFQKAGFDRLFYTQGDYGLFQCSECCKTFENEDPCDLLPVCPHCG--KPLTMNLRSDDKFVEAAERY
ENFLNLNVLFLELGVGYNT-PVIKYPFWQVNPKAVYACVNYGEAIGPKQQAVYFNGDIGKVLDELD-------------
>tr|A0A0J1GDE3|A0A0J1GDE3_9FIRM Uncharacterized protein OS=Robinsoniella sp. RHS GN=RHS_0782 PE=4 SV=1
------------------------------DKLRSALAQADTVIIGAGAGLSTSAGFV-FQENHGFAEKYHFNDMYSGGFYPDTLEEHWAYWSRYIWINR
-YTQAPKPVYDQLFDLVK--DKDYFVLTTNVDHQFQKAGFDRLFYTQGDYGLFQCSECCQTYDNEEPTELIPHCPVCG--KPMSMNLRADNTFAQAAERY
SEFLNTKVLFLELGTGMNT-PSVKFSFWRNWSNATYACINMGEAYAPDAKSICINEDIGSVLKQI--------------
>tr|G2GTD6|G2GTD6_STRSL Uncharacterized protein OS=Streptococcus salivarius M18 GN=SSALIVM18_04431 PE=4 SV=1
------------------------------QDAKRIIEEADKIVIGAGAGLSAAAGLT-FEVFKDYIARYGMQDMYSAAFYPETAEERWGYWAKHIYHNR
-YQPEGFSLYRDLFDLVK--DKDYFVITTNVDGQFMKTGFARFFEVQGNYGEWQCSVCRQVFDNRGPTDLIPYCPHCG--APMTMHLRVDQAFVQSYEAY
LGFLDQKVVFLELGVGYNT-PTIRYPFEKAPLSSTGSRLSLPTRPLFTKRSKRIDSDSAQSLPVAR-------------
>tr|I2NFF1|I2NFF1_STRPA Uncharacterized protein OS=Streptococcus parasanguinis F0449 GN=HMPREF9971_1452 PE=4 SV=1
------------------------------QEAKKIIEEADKIVIGAGAGLSAAAGLT-FEVFKDYIARYGMQDMYSAGFYPETPEERWGYWAKHIYHNR
-YQPEGLSLYRDLFDLVK--DKDYFVITTNVDGQFMKTGFARFFEVQGNYGEWQCSVCRQVFDNEGPTDLIPYCPHCG--TPMTMHLRVDQAFVQSYEAY
LGFIDQKVVFLELGVGYNT-PTIRYPFEKAFPKAHLIRLNRDDLEGFAEKT-SINDDMR---EVLQ-------------
>tr|W1WIA5|W1WIA5_9ZZZZ Uncharacterized protein OS=human gut metagenome GN=Q604_UNBC18704G0008 PE=4 SV=1
------------------------------KKLREVLDEADAVVIGAGSGLSTSAGLT-FEKYSDFIEKYNIPDMYSGGFYPETLEEYWAWWSRHIYYNR
-YIDVPKPVYEHLLNLVK--NKDYFVITTNVDHCFQRSGFDRMFYMQGDYGLWQCSECHQTYDNEEPSDLIPYCPVCQ--KPMTMNLRCDNTFVQAKNRY
DNFINSKVVYLELGVGANT-PVIKYPFWKMNPKATYVCINYGEAIAPGEQSICIDDDIGDVINKLQ-------------
>tr|G9R333|G9R333_9FIRM Uncharacterized protein OS=Coprobacillus sp. 3_3_56FAA GN=HMPREF1021_02327 PE=4 SV=1
------------------------------LKLSQAIKKCDAILIGAGAGLSSAAGLS-FKKYNDFITKYHLQDMYSAGFYPPSLEKYWAYWSRHIYYNR
-YLEAPKDTYKKLLNLLI--NKDYFVITTNVDHQFQIAGFIKLFYTQGDYGLWQCSKCHQTYDNYEPSSLIPYCPICN--APMTMNLRCDKTFVQAQERY
YHFLYSKIVYLELGVGYNT-PGIKYPFWQINPKAIYACINQDIIDLPSKQTIMINDNIHNVLS----------------
>tr|D6KHA8|D6KHA8_9FIRM SIR2 family protein OS=Veillonella sp. 3_1_44 GN=HMPREF0873_00137 PE=4 SV=1
------------------------------ERVKDFLNTADAVLVGIGAGMSTAAGLT-FHKYDDFHKKYGITDMYSGGFYSESMEEYWAWWSRHIFYNR
-YDILAGEPYIRLMELLQ--NKNYFVITTNVDHQMQFAGVDRFYYMQGDYGLWQCSECHQTYDNEEPTELIPHCPRCG--ELMTMNLRVDGAFVQAQKRY
ASFIDKKTVLLELGVGYNT-PMIKYPFMRHNIDTLYVPVNIEKQSIPFQNTVLFNKDIQKVLNDLL-------------
>tr|R5QN35|R5QN35_9FIRM Uncharacterized protein OS=Coprobacillus sp. CAG:235 GN=BN550_01213 PE=4 SV=1
------------------------------IQLSKCIEECDAIIIGAGSGLSTAAGLT-FEKYSDFIKKYHLRDMYSAGFYSESLEEHWAYWSRHIYYNR
-YINSPKDTYQKLLELVK--DKDYFVLTTNVDHQFQRAGFDRLFYTQGDYGLWQCSVCHQTYDNEEPTELVPRCPHCH--APLTMNLRCDNTFVQAYNRY
EDFLNCKVLYLELGVGGNT-PAIKYPFWKSNKNAIYACINYEDISCPIKRSLLIKGDIDQVINNLL-------------
>tr|A0A0J8YZU8|A0A0J8YZU8_9FIRM SIR2 family protein OS=Coprobacillus sp. 8_1_38FAA GN=HMPREF0979_01371 PE=4 SV=1
------------------------------KDIYAKIQEADAIVIGAGAGLSTAAGYE-FKKYSDFEEKYGIHDMYSGGFYPDTLEEYWAWWSRQIYYNR
-YVDYL-ELYQKLYQLVQ--DKDYFILTTNVDHCFQKTGFERLFYTQGDYGLFQCSSCHNTYDNKKPTSLVPHCPRCG--KPMTMNLRCDDTFVEAYLRY
QDFIDLKIVYLELGVGQNT-PGIKYSFFRENKKATYICINK-DAYCPRKRAYCINEDIKDIIG----------------
>tr|R6QA09|R6QA09_9FIRM Uncharacterized protein OS=Eubacterium sp. CAG:274 GN=BN582_01845 PE=4 SV=1
------------------------------EKLKEKIEKADVIVIGAGAGLSTSAGLT-FEKYSDFKRKYGIKDMYSGGFYPNSLEEYWAWWSRHIYVNR
-YDIKPTEVYINLLKLVE--NKNYFVITTNVDHQFQISGFDRLFYTQGDYGLWQCSKCHNTYDNEEPTELVPYCPICG--APMNMNLRCDDSFVQAEQRY
EDFINMNVVFLELGVGGNT-PVIKYPFWRENENSTYCCINLSEIYIPREQSICIESDIGDVLKRMV-------------
>tr|A0A099TGN4|A0A099TGN4_9HELI Sir2 silent information regulator family NAD-dependent deacetylase OS=Helicobacter sp. MIT 05-5293 GN=LS68_00965 PE=4 SV=1
------------------------------SKIKSELEAVDAILIGAGAGLSASAGLT-FFKYADFHAKYGITDIYLGGFYPDTLEEYWAWWSRHILYNR
-YEQPPLVVYENLLSFVK--NRNYFVLTTNVDHCFQNAGFDRLFYTQGDYGLLQCSVCHNTYDNEDPTELIPYCPVCG--KPMTTNLRSDDKFVQACKRY
EDFIDKRILLLELGVGGNT-PAIKYPFWRMNPQAMYVCINNGEAFAPKAQSLCLNGDIGKVLEMMK-------------
>tr|R9KFL7|R9KFL7_9FIRM Uncharacterized protein OS=Lachnospiraceae bacterium A2 GN=C810_04556 PE=4 SV=1
------------------------------DRLKDELGNADAVLIGAGAGLSTAAGLT-FRKYSDFADKYGIRDMYSGGFYSNSVEEHWAWWSRHIWYNR
-YQPGSTEVYRNLYDLIN--EKDYFVLTTNVDHQLQLAGFDRIFYTQGDYGLWQCSECHQTYDNEEPTELIPHCPVCG--KPMSMNLRCDDTFVQAGQRY
SDFVKLHILYLELGVGANT-PVIKFPFWRENEKAVYACINFGEASCPKKQSICIDEDIKKVLSALV-------------
>tr|R6RK56|R6RK56_9FIRM Uncharacterized protein OS=Firmicutes bacterium CAG:424 GN=BN652_02068 PE=4 SV=1
------------------------------KRLKQAIDNADAILIGAGAGLSASAGYT-FQKHADFNQKYGISDMYSGGFYPETLEEYWAWWSRHIYYNR
-YDQPQNKVYQMLLKLIQ--DKDYFVLTTNVDHLFQINHFDRLFYTQGDYGLWQCSKCHQTYDNEAPSDLIPYCPVCG--APMTMNLRCDNSFVQANTRY
EDFVNSKLLLFELGVGNNT-PVIKYSFWKINPNAVYSCVNLSDAYAPTQQSVCLDGDIGAILKKVS-------------
>tr|R6MJE6|R6MJE6_9FIRM Uncharacterized protein OS=Firmicutes bacterium CAG:41 GN=BN647_00326 PE=4 SV=1
------------------------------IRLKEKLDKADAVVIGAGAGLSTAAGFT-FEKYSDFKQKYGFTGMYSGGFYSETLEEYWAYWSRYIYINR
-YMDIPNNLYDMILSLVN--GKDYFVITTNVDHCFQKACFDRLFYTQGDYGLLQCPTCCNTFDNEDPTELIPLCPHCK--KPLTTNLRCDNSFVQAAERY
DNFLGQNIVFLELGVGYNT-PAIKYQLWRSNKNSIYVCINKGESVCPEKQSIYLDEDIYKVIK----------------
>tr|A0A078MCJ3|A0A078MCJ3_9STAP Uncharacterized protein OS=Jeotgalicoccus sp. 13MG44_air GN=BN1048_02255 PE=4 SV=1
------------------------------EILKGLIDEADAVVVGIGAGMSAADGFT-FKNNPDFIEKYNWLDMLQASLFKPTLEEYWAFQSRFIVLNY
-LEQPAGEAYIALKEMIE--NKPYHVITTNADNAFYAADYNKVLYYQGEYVRMQCSDCHDTYRDDEPSELIPYCPKCG--APMEKNKRTEKGMVEQRDDY
NAFLKGKVMYLEIGVGHTT-PQIKHPFWRRNENALFVTMNQKTYRIPESQTVFLTEDIGETILNAH-------------
>tr|S9ATK1|S9ATK1_STRAG Deacetylase SIR2 OS=Streptococcus agalactiae FSL C1-487 GN=SAG0007_03925 PE=4 SV=1
------------------------------EILSQLIEESDAIVVGIGAGMSAADGFT-FEEAPDFIAKYQLLDMLQASLYDEDWEEYWAFQSRFVALNY
-LDQPVGQAYLDLKDILA--KKEYHIITTNADNAFAVADYNKVFHIQGEYGLWQCSQCHQTYRNDQPSNLIPKCPKCD--QPFEINKRNEKGMVEQRQRY
ENFLNDKVLYLEIGVGHTT-PQIKHPFWRSNENSLFVTLNHKHYRIPQSRSVQLTQHIAELIAEAK-------------
>tr|U2RCI4|U2RCI4_9FIRM Uncharacterized protein OS=Oscillibacter sp. KLE 1745 GN=HMPREF1546_00965 PE=4 SV=1
------------------------------EQLKGALASADAVVVGAGAGLSASAGMT-FRRYSDFQSRYDIQDMYSGGFYPESLEEYWAWWSRQILVNR
-YEKAPKPVYGDLLKLIK--DKDYFVLTTNVDHQFQLAGFDRLFYTQGDYGLWQCSKCHQTYDNEEPTELVPRCPRCG--RPMAMNLRCDDTFVQAARRY
EDFLGRRLLFLELGVGGNT-PGIKYPFWKLNRSAAYACINQKESYIPPGRSVCIPADIGHILKRLT-------------
>tr|U2EU32|U2EU32_CLOS4 Uncharacterized protein OS=Clostridium sp. (strain ATCC 29733 / VPI C48-50) GN=HMPREF0262_02946 PE=4 SV=1
------------------------------------------MVVGAGAGLSTSAGLT-FEKNADFKARYGIGDMYSGGFYPGSLEEYWAWWSRHILLNR
-YDQPPGGPYLDLLRLLA--GRDYFVLTTNVDHQFQLAGFDRLFYTQGDYGLWQCSRCHDTYDNEEPGELVPRCPVCG--APMAMNLRCDGRFVEAALRY
RAFLGRRLLFLALGVGGNT-PVIKYPFWQANPRATYCCINLGEASAPRGRAICIDADIGQALAALD-------------
>tr|R9M370|R9M370_9FIRM Uncharacterized protein OS=Oscillibacter sp. 1-3 GN=C816_02209 PE=4 SV=1
------------------------------------------MAVGAGAGLSASAGLA-FKAHKDFAEKYGIEDMYSGGFYPASPEEYWAWWSRHIMVNR
-YARAPGPAYGDLLKLLE--GRDYFILTTNVDHQFQLAGFDRLFYTQGDYGLFQCSGCCQTWDNEGPAELIPRCPRCG--RPAAMNLRADDAFVQAARRY
EDFLRGAVLYLELGVGMNT-PGIKYAFWQANPEAVYACVNLGQSFCPAGRSVCLDGDIGRVLAALR-------------
>tr|A0A0A8B321|A0A0A8B321_9ACTN Sir2 silent information regulator family NAD-dependent deacetylase OS=Coriobacteriaceae bacterium 68-1-3 GN=JI75_03575 PE=4 SV=
------------------------------GRLKEAIESADAIVVGAGAGLSTAAGFT-FERLGDFAAKYGIRDMYSGGFFPAAPEERWAWWSRHIWCNR
-YEPAPKDTYGKLLELLD--GRDFFVLTTNVDHQFQQAGFPRLFYTQGDYGLWQCSECHDTYDNYAPSELVPTCPRCG--KPMTMNLRADGTFVEAAARY
RAFLTGRVLYLELGVGMNT-PIIKYPFYRYNPEAIYACVNYGEAYTAVDRSIVLDADIDAVLGELL-------------
>tr|A0A096DFB9|A0A096DFB9_9FIRM Uncharacterized protein OS=Clostridium orbiscindens 1_3_50AFAA GN=HMPREF9460_01261 PE=4 SV=1
------------------------------EQVRQALHEADAVVIGAGSGLSTSAGLT-FQEHGDFIQKYKIQDMYSGGFYPDTLEEHWAWWSRHILINR
-YEKAPKPVYDELLKLIH--DKDYFVLTTNVDHQFQLAGFDRLFYTQGDYGLWQCSECCQTWDNEEPTELVPHCPVCG--RPMTMNLRCDNTFVQAYSRY
EDFLNAKVVYLELGVGGNT-PVIKYPFWKYNAKAFYVCVNLSESCCPKKRSICLNRDIGTALHELY-------------
>tr|R6H8E8|R6H8E8_9FIRM Uncharacterized protein OS=Firmicutes bacterium CAG:137 GN=BN490_01060 PE=4 SV=1
------------------------------AALKELICHADAILVGAGAGLSASAGLT-FEQNADFRQKYGISDMYSGGFYPDTLEEYWAWWSRQIYINR
-YDITPGRPYRELRKLIT--GKDYFVLTTNVDHQFQLAGFDRLFYTQGDYGLWQCSRCHRTYDNEDPTGLIPRCPVCG--APMTMNLRCDGTFVQAALRY
EDFISLSILYLELGVGMNT-PGIKYNFWQQNANARYVCINKDMAFAPRGQSLFLEADIGKVLDELT-------------
>tr|A0A073IPU2|A0A073IPU2_9BACT Uncharacterized protein OS=Synergistes jonesii GN=EH55_09790 PE=4 SV=1
------------------------------RLLKREIETSDALLVGAGAGMSAAAGMT-FEKNADFHKKYGITDMYSGGFYRETPEEYWAWWSRHILLNR
-YEAGVGKTYSDLFELLR--DKDYFVLTTNVDHQFQLAGFDRLFYTQGDYGLWQCSECHQTYDNEKPPKLLPLCPLCG--ALMTMNLRSDDKFVQAAERY
AAFLDTHLLLLELGVGSNT-PLIKYPFWQANSNAVYACVNSGEAFIPRSRGIRLNADIGKVLNELK-------------
>tr|C0E4V9|C0E4V9_9CORY Uncharacterized protein OS=Corynebacterium matruchotii ATCC 33806 GN=CORMATOL_02034 PE=4 SV=1
------------------------------ETIANELEQADKVLIGAGAGLSAADGFE-FQEHGDFAAAYGMTDAYTAGFYPPDETEKWAYWSRYINYNR
-YLKKPGSVYQNLLALVH--DKDYFVLTTNVDHCFQRAHFNRLFYTQGDYGLWQCATCHQTYDNHDPAELVPRCPRCG--GQMTTNLRADDTFVQAAKRY
QNFAQSRTLLLELGVGMNT-PAIKYPFWRYNPRAHYATVSL-DAVAPKERSTVVQADIASVLRLLA-------------
>tr|I7WIV6|I7WIV6_STRCB Uncharacterized protein OS=Streptococcus canis FSL Z3-227 GN=SCAZ3_05705 PE=4 SV=1
------------------------------EQLAQLIKEADALVVGIGAGMSAADGFT-FETAPDFIAKYQFLDMLQASLFDEDWQEYWAFQSRFVALNY
-LDQPVGQSYLDLKEILE--TKDYHIITTNADNAFWAANYDKIFHIQGEYGLWQCSQCHQTYQDDHPSQLIPHCPKCG--APFEINKRNEKGMVEQKARY
ETFLEDKVLYLEIGVGHTT-PQIKHPFWKSNPNALFVTLNHKHYRIPLQQSLELTEHIAQLISAAK-------------
>tr|H7EKU8|H7EKU8_9SPIO Putative uncharacterized protein OS=Treponema saccharophilum DSM 2985 GN=TresaDRAFT_0962 PE=4 SV=1
------------------------------EKIKSVLENAEALVVGAGAGLSTSAGFT-FEKYADFQARYGFSDMYTGGFYPKTLEEHWAYWSRYIMINR
-YMDATIPVYEELFELVK--NKNYFVLTTNVDHCFQKAGFDRLFYTQGDYGLWQCSECHKTYDNQLPSELVPRCPVCG--KPMSMNLRADDTFVEAAGRY
EDFLYGKIVYLELGVGGNT-PGIKYPFWNYNPKAKYICINKGEAVVPKNQSICVNNDIYEVLKEL--------------
>tr|A7VYK9|A7VYK9_9FIRM Uncharacterized protein OS=[Clostridium] leptum DSM 753 GN=CLOLEP_03687 PE=4 SV=1
-------------------------------------------MIGAGAGLSASAGFT-FEKFGDFIEKYGLSDMYSGGFYPETLEEHWAYWSRYIYINR
-YMDAPKPIYNELLRLVD--GKDYFVLTTNVDHCFQKAGFDRLFYTQGDYGLWQCSKCHQTYHNETPGKLVPYCPVCG--APMAMNLRTDMTFVEAARRY
EDFLGLHILFLELGVGSNT-PAIKYPFWKYNPKTVYACINLGEAVCPDKQSICINTDLAGVITALK-------------
>tr|G9PHC9|G9PHC9_9ACTO Uncharacterized protein OS=Actinomyces graevenitzii C83 GN=HMPREF0045_01657 PE=4 SV=1
------------------------------SRLLEALTNADAVVVGAGAGLSTSAGFT-FQKYADFIEAYGFSDMYSAGFYPKTLEEQWAYWSRHIWYNR
-YVPAPKDTYDKLAQLLA--GKYFFVLTTNVDHQFQLAGFPRLFYTQGDYGLWQCSQCHATYDNYESSELVPHCPRCG--EPMSMNLRADHTFVEAAQRY
QDFMADKVLYLELGVGANT-PGIKYPFWQYNPLATYACINFGQAQAPIERSILIDGDIHQALTQAL-------------
>tr|A0A0K1F0G6|A0A0K1F0G6_9ACTN Sir2 silent information regulator family NAD-dependent deacetylase OS=Olsenella sp. oral taxon 807 GN=ADJ70_02615 PE=4 SV=1
------------------------------KELVEVIHAAEAVVVGAGSGLSTAAGLT-FRRHSDFIEARGFTDMYTAGFFPPTLEEQWAYWSRHIWYNR
-YVKAPKDTYKKLLKLLD--CKDFFVLTTNVDHQFQLAGFPRLFYTQGDYGLWQCSVCHNTYDNREPTELVPHCPKCD--EPMSMNLRADDTFVEAANRY
SDYLEGRVLYLELGVGMNT-PAVKYPFWRYNPQARYACVNYREAYAPAGRSFLLSGDIDKVLFEAL-------------
>tr|E1QYB5|E1QYB5_OLSUV Uncharacterized protein OS=Olsenella uli (strain ATCC 49627 / DSM 7084 / CIP 109912 / JCM 12494 / VPI D76D-27C) GN=Olsu_0253 PE
------------------------------TRLVEAIASADAVVVGAGAGMSTAAGLT-FERLPDFIERYGFADMYSAGFYPPTPEEHWAYWSRYVWCNR
-YEAAPKDTYGKLLRLLG--GKDLFVLTTNVDHQFQLAGIPRLFYTQGDFGLWQCSVCHDTYDNFGPSELVPHCPVCG--RPMAMNLRADSTFVEAATRY
REFLRGRVVYLELGVGMNT-PVVKYPFWRYNPDATYVCANYGETYAPDGRSILLDADIDATLSAAL-------------
>tr|R7CC19|R7CC19_9CLOT Uncharacterized protein OS=Clostridium sp. CAG:62 GN=BN737_00110 PE=4 SV=1
------------------------------NRLKEKMEKADAVIIGAGAGLSTSAGFT-FNRYSDFIAKYGFSDMYSGGFYPETLNEHWAYWSRYIYINR
-YQDAPRPVYENLLKLVK--DKDYFVLTTNVDHCFQKAGFDRLFYTQGDYGLFQCSKCCSTFDNEVPDYLIPRCPHCG--APLSMNLRADSTFVEAASRY
DDFLNLNVLFWELGTGYNT-PVIKYPFWQAWPDAFYACINLGQTEVPLNKSIGISKDAGEVIENLL-------------
>tr|G5KG79|G5KG79_9STRE Uncharacterized protein OS=Streptococcus urinalis 2285-97 GN=STRUR_1240 PE=4 SV=1
------------------------------ELLGRLMKEADAIVVGIGAGMSASDGFT-FEEAPDFIKKYGFFDMLQASLFDESWEEYWAFQSRFVVLNY
-LDQPVGQSYLDLKSILA--RKDYHIITTNADNAFDIAGYDKVFHIQGEYALWQCSQCHQTYRDDNPQNLVPKCPKCH--APFEINKRNVKGMVEQKKRY
QQFLSGKILYLEIGVGNTT-PQIKHPFWKANPDSLMISLNHKSYRIPKKQFLCLDQDIASLITETK-------------
>tr|K1LUX9|K1LUX9_9LACT Uncharacterized protein OS=Facklamia ignava CCUG 37419 GN=HMPREF9707_01561 PE=4 SV=1
------------------------------DLLKGLIEEAEVVVPGIGAGMSAATGFT-FEEAPDFIEKYNFFDMLQAFLADEDWEEYWAFQSRFALLNY
-FDQPVGQSYVDLKDILE--GKTYHIITTNADNAFYAANYDKVFYIQGEYGLWQCSDCQQTYQDEAPTELIPYCPHCH--APLEVNKRDVRGMVEQEAAY
TDFLGKKILFLEIGVGHTT-PQIREPFQEANPNALYVTMNQKRYRIPPPQSVRITEDIYTL---FN-------------
>tr|A0A0R1L2Q1|A0A0R1L2Q1_9LACO Sir2 silent information regulator family NAD-dependent deacetylase OS=Lactobacillus sunkii DSM 19904 GN=FD17_GL001486 PE=4 SV=1
------------------------------DTLRSLIDQADATVIGVGAGMPAADGFS-FEDNADFIEKYHFYDMLQAFLAKEDWSEYWAFESRFVLLNG
-IDQPEGKLYHHFQQFLE--NNEYTILNTNGDNTLEKAHFDRVFNYQGQFSRMQCSKCTPTYRDDDPEDLIPRCPNCG--APLEVNKRTDQGMVEEEKNY
HDFLGKKVLNLEIGVGHTT-PWIREPFWKKSPDAMYVMVNQKDYLIPDGQKVRLNGDIAQVVGQL--------------
>tr|F2I857|F2I857_AERUA Uncharacterized protein OS=Aerococcus urinae (strain ACS-120-V-Col10a) GN=HMPREF9243_0578 PE=4 SV=1
------------------------------GLLRALMEEAQAILVGIGAGMSAADGFT-FEQAPDFIEKFNLFDMLQASLYDPSLEEYWAFASRFAIMNG
-IEQEAGKAYQHFNQYLQ--GKNYFIITTNADNAFPKAGYDKVHYYQGKYVLMQCKKCQPTYRDDAPSELVPYCPNCG--APLELNKRTENGMVEHQAAY
EDFVYDKILYLEIGVGNTT-PQIRQPFQAKNPKALYVMMNQKPYHIPPSQSLRLTDDIQKTLCEL--------------
>tr|A0A0R1YSQ5|A0A0R1YSQ5_9LACO Uncharacterized protein OS=Lactobacillus parafarraginis DSM 18390 = JCM 14109 GN=FD47_GL002368 PE=4 SV=1
------------------------------DQLRSLITEADATVIGIGAGMPAADGFM-FEKPADFIEKYHFYDMLQGFLADEDWSEYWAFESRFVLLNG
-IEQPEGKLYHHFQQFLD--GQNYTIINTNGDNTLEKAHFDRVFNYQGQYSRLQCSKCTPTYRNDDPEDLIPRCPNCG--APLEVNKRTDAGMVEESTLY
HQFIGKKVLFLEIGVGNTT-PWIRQPFWRSNPNARYVMVNQKDYKIPENQSFRLTQDMNDIIGNL--------------
>tr|C2D2Z3|C2D2Z3_LACBR Uncharacterized protein OS=Lactobacillus brevis subsp. gravesensis ATCC 27305 GN=HMPREF0496_1915 PE=4 SV=1
------------------------------DQLRALIDEAEATVVGIGAGMPAADGFS-FETHADFIQKYHFYDMLQAFLADEDWSEYWAFESRFVLLNG
-IEQPEGKLYHHFRAFMD--HGHYTIINTNGDNTLEKAHFDRIFNYQGQYSRMQCSKCTPTYRDDDPESLIPKCPNCG--APLEVNKRTDAGMVEEAKNY
HDFLGRKVLYLEIGVGNTT-PWIRKPFWKRNPNALYVMLNQKDYQIPEGQSLRLNQDMTQVIGHL--------------
>tr|K9EPY6|K9EPY6_9LACT Uncharacterized protein OS=Alloiococcus otitis ATCC 51267 GN=HMPREF9698_01560 PE=4 SV=1
------------------------------SQLGQLIDQADAILVGAGAGLSAAAGFT-FTQAPDFIAKYNFFDMLQAFLDDEDLREYWAFQSRFALLNY
-FDQAVGQAYLDLKDILE--GKDYHVLTTNADNAFEAGGFDKVFRIQGEYGLWQCSRCHQTYQDEAPEDLIPYCPKCG--APLEVNKRDVHGMVEQEERY
RAFLEGKIVYLEIGVGVTT-PQIRKPFQDSNPQALYVTMNQRPYRISPEQAVRITDDISQV---LH-------------
>tr|G9PS09|G9PS09_9BACT Uncharacterized protein OS=Synergistes sp. 3_1_syn1 GN=HMPREF1006_02109 PE=4 SV=1
------------------------------ERLREALAGADAVLVGAGSGLSAAAGLV-FERNADFIAKYGFTDMYSAAFHRPSLEEHWAYWSRHICLNR
-YDRPVGAPYRDLLAAVR--GRDHFVLTTNVDHLFADAGFERLFPTQGDYGLWQCSRCHDTYGNETPQALVPRCPRCG--APLAMNLRVDGSFVEAKGRY
LAFPGLRVVFLELGVGGNT-PGIKYPFWRLNPDSLYICANRGEAFAPAERALCIDGDIAPLLAAAR-------------
>tr|B7AUW2|B7AUW2_9FIRM Putative uncharacterized protein OS=[Bacteroides] pectinophilus ATCC 43243 GN=BACPEC_02510 PE=4 SV=1
------------------------------KAALDRIEGADAVVIGAGAGLSTSAGFT-FEKYADMERAYGFHDMYSGGFYNDSSEKLWGFWCRYIYINR
-YMDAPKPVYQDIFERVK--NKNYFVLTTNVDHCFQKAGFDRLFYTQGDYGLFQCSQCHKTYDNEEPPELVPVCPKCG--RPMSMNLRSDCTFVQAAERY
ERFLNTKTAFVELGVGYNT-PGIKYPFWQENPKASYICINKGEAYAPRDRSVCIDGDIYDYTDRNE-------------
>tr|E8LBB5|E8LBB5_9FIRM Uncharacterized protein OS=Phascolarctobacterium succinatutens YIT 12067 GN=HMPREF9443_00124 PE=4 SV=1
------------------------------KCLQAALQECEAVVIGAGSGLSTAAGYT-FQKYADFAEKYGIRDMYSGGFYPPTQEEFWGYWSRYIFINR
-YMDAPKPVYEKLLRLVA--DKDYFVITTNVDHCFQKAGFDRLFYMQGDYGLFQCSECCRTYDNEISAELIPYCPICG--KPMTMNLHCDATFVQASQRY
KEFLGLRVLFLELGVGMNT-PAIKFPFWHNWENAAYACINLGEAYAPEAKSICINEDIGVALQKLI-------------
>tr|D5U7I3|D5U7I3_BRAM5 Uncharacterized protein OS=Brachyspira murdochii (strain ATCC 51284 / DSM 12563 / 56-150) GN=Bmur_0671 PE=4 SV=1
------------------------------KKLKSSIEKSDYILIGAGAGLSVSAGFP-FNKYSEYKDRYGLTDMYSAGFYKPTLEDFWGYFSLFVYVNR
-YDIPADETHLNLLEIIK--NKNYFVITTNVDGRFEEAKFDKLFKVQGDYSLFQCSVCRQTFYNEKSKELIPKCPHCG--KNMTMNLRCDNTFVQSMDRY
KKFLNKNILFLELGVGYNT-PAIKYSFWDLNENSIYASVNLNDSYAPDERSICINDDISKVLEYIK-------------
>tr|H1HUR1|H1HUR1_9FIRM Uncharacterized protein OS=Stomatobaculum longum GN=HMPREF9623_01331 PE=4 SV=1
------------------------------KNLQAALSEADTVVIGAGAGLSASAGFI-FEKYSDFAAKYGIKDMYSGGFYPATPEEHWAYWSRYIYINR
-YMDAPKPVYETLLNLVA--DKDYFVITTNVDHCFQKAGFDRLFYTQGDYGLFQCSECCQTFENEAPTELLPVCPHCG--KPLTMNLRSDDRFAEAAERY
ENFLGGKILFLELGVGYNT-PVIKYPFLQANPNAIYICINQGQAVCMQKRSVCIDADIGQVLQSLY-------------
>tr|A0A060RGQ2|A0A060RGQ2_9STRE Uncharacterized protein OS=Streptococcus gallolyticus GN=BN963_SGAL_00727 PE=4 SV=1
------------------------------NDIVKKLEKADAVLIGIGAGLSASAGLT-FDNYSDFKEKYGIEDMYSGGFYPATKEEYWAWWSRHIFINR
-YEAPVGQPYIDLLDIVK--HKDYFILSTNVDHQVQKAGFDRLFYTQGDYGLMQCSVCHYNYDNKDPSNLIPTCPRCG--APMTNNLRIDNRFVEAQKRY
SEFLKKTIIYLELGVGMNT-PGIKYPFMQYNPKATFITLNQETFKYPDKQLIQLDGDIGKNLQAIR-------------
>tr|A0A0R1TRE6|A0A0R1TRE6_9LACO Sir2 silent information regulator family NAD-dependent deacetylase OS=Lactobacillus apodemi DSM 16634 = JCM 16172 GN=FC32_GL000
------------------------------AEVKEFIEDADVILIGIGAGMSAAAGLQ-FEKHADFKDKYGITDMYSGGFYPQTKEEYWAWWSRHVYINR
-YKPKALKPYLDLLKLVK--DKNYFVLTTNVDHQTQKAGFDRLFYTQGDYGLFQCSVCHNTYDNEAPTELIPKCPKCG--ADMTMNLRIDNRFVEAQARY
EKFLQKKIVYLELGVGMNT-PGIKYPFLQSNPQAEFITFNAQRFEYPVPQIIQIVGDIAENLSELV-------------
>tr|S5ZZ45|S5ZZ45_9SPIO Uncharacterized protein OS=Treponema pedis str. T A4 GN=TPE_0987 PE=4 SV=1
------------------------------SIIADTLKKADAVIAGIGAGMSTAAGFT-FEKYSDFQARYGIQDMYSGGFYPPSLEEYWAWWSRHIYYNR
-YDVPIGEPYIALFNILQ--DKNYFIITTNVDHQIQKAGFDRLFYTQGDYGLWQCSVCHNTYNNEQPSALIPYCPVCA--APMTMHLRSDGTFVEAHKRY
TDFLHKRNVFLELGVGNNT-PGIKYPFMKWNNNARYISINMEAYHIPPEQTLFIQGDIKHVLKDIS-------------
>tr|H1BJQ9|H1BJQ9_9FIRM Uncharacterized protein OS=Eubacterium sp. 3_1_31 GN=HMPREF0984_00616 PE=4 SV=1
------------------------------EKLHALLQEADAILIGAGAGLSTAAGLR-FYRYQDFIDAYHFTNMYEAGFYPATLEEYWGYWSRHIYHNR
-YAAQVNTVYADLLSLVK--DKNYFVITTNVDHQFQLHGFARLFYTQGDYGLLQCSHCHATYDNEKPKELIPYCPYCH--APMTVNLRYDANFCEAQKRY
QQFLDDHIVYLELGVGNNT-PGIKYPFWQHNPQAYYVIINQLEAYCPMKQSLVIEKDIASVLKEIK-------------
>tr|D0BLX4|D0BLX4_9LACT Uncharacterized protein OS=Granulicatella elegans ATCC 700633 GN=HMPREF0446_00977 PE=4 SV=2
------------------------------QQLKSLFEEADAIVVGIGAGMSAADGFT-FESAPDFIEKYQLLDMLQASLFQASWEEYWSFQSRFIALNY
-LDQPVGAAYVELKEMLE--TKPYHIITTNADNAFEVAGFDKVFHIQGEYGLLQCSQCHPTYRKDEPYELIPFCPECG--APLEINKRNEKGMVEQKAHY
DSFLTGKVVYLEIGIGFTT-PQIKTPFQKTNPNAVYVSMNHKHYRVPLNRTLLLSENIAILIHETH-------------
>tr|C5NWN5|C5NWN5_9BACL Uncharacterized protein OS=Gemella haemolysans ATCC 10379 GN=GEMHA0001_1175 PE=4 SV=1
------------------------------EKLAQLIDEAEAIVIGIGAGMSAADGFT-FTSNKDFVEKYKFLDMLQASLFDPSSQEYWAFQSRFVLLNY
-FDQPVGDSYLALKNILK--DKNYHIITTNADNAFDVAGYDKVFHIQGKYGLMQCSKCHATYQDEADYRSIPLCPECG--APLEVNKRNEKGMVEHLDKY
NEFLDKKTLFIEIGVGFTT-PQIKYPFYRDNPNALMITMNQKKYQFPESRVLWFNQNSKDLTLDVE-------------
>tr|C8NG25|C8NG25_9LACT Uncharacterized protein OS=Granulicatella adiacens ATCC 49175 GN=HMPREF0444_0870 PE=4 SV=1
------------------------------SLLADLFQEADAIVVGIGAGMSAADGFT-FEDAPDFIEKYQFLDMLQASLFHPSWEEYWAFQSRFIALNY
-LDQPVGQSYVELLEMLK--AKPYHIITTNADNAFWVAGYDKVYHIQGEYGLFQCNQCHATYSDDAPYELIPFCPECG--APLEINKRNEKGMVEQKARY
DAFLNDKVLFLEIGVGFTT-PQIKNPFQKQNPNTLFVSMNHKHYRIPLEQTVQLSENIAPLIHGTY-------------
>tr|H3NCL2|H3NCL2_9LACT Uncharacterized protein OS=Dolosigranulum pigrum ATCC 51524 GN=HMPREF9703_00293 PE=4 SV=1
------------------------------EKLCELIAEADAVVVGIGAGMSAADGFL-FTDHADFIEKYGLIDMLQASLYDESITEYWAFQSRFIALNY
-LDQPVGPSYLALKSLLA--DKPYHIITTNADNAFWVADYDKVFHIQGEYGLMQCSQCHATYRKDDPYELIPYCPRCG--AYLEVNKRNEKGMVEQLERY
EAFLTGQVLYLEIGVGFTT-PQIKQPFTDENPAAIYVPMNQKRYRLPQQRTIRLTDDIQQTLTQAN-------------
>tr|B0MEF3|B0MEF3_9FIRM Uncharacterized protein OS=Anaerostipes caccae DSM 14662 GN=ANACAC_01948 PE=4 SV=1
------------------------------RVLKQKLSQAEAIVIGAGAGMSAAAGLL-FEKNKDFIERYGLRDMYSAGFYPPSPEEKWAYWSRHIYLNR
-YDMPSGKAYTDLFQAVR--DKNYFVLTTNVDHQFWLSGFERIFAVQGDYGLFQCKKCHPLYDNETPKSLIPKCPVCG--GEMEVNIRKDEYFIEAAGRY
KRFLDKRILFLELGVGMNT-PGIKYPFWQANPKAVYVCVNSGEAYSPRAQSICIDGDIGKLIDICV-------------
>tr|C0D3F1|C0D3F1_9FIRM Uncharacterized protein OS=[Clostridium asparagiforme] DSM 15981 GN=CLOSTASPAR_03792 PE=4 SV=1
------------------------------EMIRETLQQAQAIVIGAGAGLSAAAGLT-FRRYGDFIRKYGMMDMYSAGFYPETQEEKWAYWSRHIYYNR
-YDQPAGKTYLDLYRLVR--DQPYFVLTTNVDHQFWLAGFDRIFATQGDYGLFQCAGCHKLYDNEAPTELVPKCPVCG--GEMEVNLRCDGNFVEASVRY
REFLGRRVVFLELGVGMNT-PGIKFPFWQAWPQAFYICVNLDQAWAPEDCSLCLNGDLSRILEKL--------------
>tr|N9XTQ5|N9XTQ5_9CLOT Uncharacterized protein OS=Hungatella hathewayi 12489931 GN=HMPREF1093_00545 PE=4 SV=1
------------------------------STVRTFIEEAEAVVVGAGSGMSAAAGLT-FREKGDFIEHYGMTDMYSAGFYPPTQEEKWAYWSRHIYCNR
-YDVQAGKPYLDLYQLVK--DRNYFILTTNVDHQFQLAGFPRIFAAQGDYGMFQCAKCHKLYENEKPSELVPKCPVCG--GDMEVNLRCDRYFVEACAGY
TGFINRRLVFLELGVGMNT-PGIKYPFWQDEKHGFYICINQGEAWGPEEKSLYVNMDIAEALEAVR-------------
>tr|C0BYF4|C0BYF4_9FIRM Uncharacterized protein OS=[Clostridium] hylemonae DSM 15053 GN=CLOHYLEM_04843 PE=4 SV=1
------------------------------EKVKQKINEADAVVIGGGSGLSAAAGYT-FQRNAEFIARYGLKDMYSAGFYPPTKEEKWAYWSRHICCNR
-YDQEQNDLYMSIRALVE--GRDHFVITTNVDHQFQAAGFDRIFATQGDYGLFQCAKCHDLYDNEEPSSLIPKCPVCG--GDMEVHLRCDGYFVEALNRY
EEFIGNKILFLELGVGMNT-PGIKYPFWQAYEQAFYICLNKGQAWAPQEKALCIDADIADVVKSLQ-------------
>tr|U2BDJ7|U2BDJ7_9CLOT Uncharacterized protein OS=Clostridium sp. KLE 1755 GN=HMPREF1548_02818 PE=4 SV=1
------------------------------GELAALLKNADAVVVGAGSGLSAAAGLM-FTANREFIERYGLRDMYSAGFYPPTQEEKWAYWSRHIYYNR
-YDVAPGKPYLDLYALLK--DKNYFILTTNVDHQFWLAGFPRIFATQGDYGLFQCAKCHKLYNNETPSELVPRCPVCG--GYMEVNLRCDGYFVEACVRY
EDFLDGRVVYLELGVGMNT-PGIKYPFWQDNPAAVYVCINLSEACAPWERSICISEDIAQVLKELA-------------
>tr|S3LBZ5|S3LBZ5_9SPIO Uncharacterized protein OS=Treponema vincentii F0403 GN=HMPREF1222_00893 PE=4 SV=1
------------------------------EALKTALEKADALLVGAGAGLSTSAGFT-FEKNADFHAKYGFSDMYTGGFYPTTPEEHWAYWSRNIMINR
-YADAPKPVYENVCKLVD--RKNYFVLTTNVDHCFQKAGFDRLFYTQGDYGLFQCSECHQTYDNEAPSELIPYCPRCG--KPMSMNLRSDSTFVEAAQRY
ADFLDGRILFLELGVGANT-PGIKYPFQQANPQAIYACINYGEAYCFDERAICIDGDIGEVIAEFL-------------
>tr|A7B8S4|A7B8S4_9ACTO Uncharacterized protein OS=Actinomyces odontolyticus ATCC 17982 GN=ACTODO_00023 PE=4 SV=1
------------------------------TTLREAIESADAILIGAGAGLSAADGDN-FDERADFHAERGITDAYSGGFFPPTSEERWAFWSRMISLLR
-YEASPGQVYADLLNLVR--GRDYFVITTNVDHRFQNSGFDRLFYTQGDYGLLQCSACHDTYDNESPSELIPHCPRCG--EEMTTNLRIDNRFVQAAGRY
QDFLSGRVLHLEMGVGMNT-PSIKFPFWRFNPEATYACVAL-DAAAPKDRSLVIRGDIAEALASAR-------------
>tr|A8FQZ2|A8FQZ2_SHESH Uncharacterized protein OS=Shewanella sediminis (strain HAW-EB3) GN=Ssed_0653 PE=4 SV=1
------------------------------SNSRALLQECDAVLIGAGSGLSTAAGIE-FQRNPDYIAKYGMRDMYSAGFYPASLEEKWGFRSKQVKLNR
-YDTKVGDVYLKLLDLVR--HKPYFVITTNVDAQFERAGFDNIFAVQGDYGKFQCTVCHNLYDNESPSELVPYCPNCG--EPMMLHVRIDNTFVEAKQGY
SEFLNQKLLLLELGVGFNT-PTIRFPFEQRFPHTHLIRLNKHNARSLD--NLLVEGDI-------C-------------
>tr|S3K5F6|S3K5F6_TRESO Uncharacterized protein OS=Treponema socranskii subsp. paredis ATCC 35535 GN=HMPREF1221_00067 PE=4 SV=1
------------------------------ERLNEALSKADTVLIGAGAGLSTSAGFT-FEKYSDFRAKYGFTDMYTGGFYPKTLEEFWAYWSRYIMINR
-YTDAPKPVYENLRKLAD--GKNYFVLTTNVDHCFQKAGFDRLFYTQGDYGLWQCSVCHDTYDNEAPSDLIPYCPRCG--KPMSMNLRSDSTFVEASERY
GNFINEKILFLELGVGSNT-PGIKYPFWRANPRSLYACINYGEALCPDERSICIDGDIASVLEKMR-------------
>tr|S3KT66|S3KT66_TREMD Uncharacterized protein OS=Treponema medium ATCC 700293 GN=HMPREF9195_02381 PE=4 SV=1
------------------------------ERLKAALTEADTVLIGAGAGLSTSAGFT-FEKHADFRAKYGFSDMYTGGFYPTTLEEHWAYWSRYIMINR
-YADAPKPVYENLRKLID--GKNYFVLTTNVDHCFQKAGFDRLFYTQGDYGLFQCSVCHQTYDNEAPKELIPYCPVCG--KPMSMNLRADDTFVEAAQRY
ADFLNSRILFLELGVGANT-PGIKYPFQHANPQSVYVCINYGEAFSPQQRSICINGDIGEVITELI-------------
>tr|A0A0M3RKH8|A0A0M3RKH8_9ACTO Sir2 silent information regulator family NAD-dependent deacetylase OS=Actinomyces sp. oral taxon 414 GN=AM609_02525 PE=4 SV=1
------------------------------------MDKADAVVVGAGAGLSIADGDA-FAERADFIARYGFTDAYTAGFHPASPEEKWAYWSRHISLLR
-YETGPGAVYADLLALLD--GRDFFVLTTNVDHRFQKAGLPRLFYTQGDYGLFQCSACHDTYDNADPAGLVPRCPRCG--EPMSTNLRADATFVQAADRY
ARWLNGRVLHLELGVGMNT-PGIKYPFWQHNPRATYAAVSL-DPVAPRDRCVLVDADLAPVLARLA-------------
>tr|U1R1I9|U1R1I9_9ACTO Uncharacterized protein OS=Actinomyces sp. oral taxon 877 str. F0543 GN=HMPREF1550_00522 PE=4 SV=1
------------------------------AALSSLAEWADAIVIGAGAGLSIADGDA-FEERADFMEARGITDAYSGGFYPPTPEERWAFWARMISLLR
-YEASAGHVYRDLFDLVR--DHDFFVVTTNVDHRFQMAGFPRLFYTQGDYGLFQCATCHNTYDNRGPSPLLPRCPRCS--GPMTTNLRVDGRFVQAARRY
ADFCRGRVLHLELGVGANT-PGIKYPFWRLNPEARYATVAL-DACAPHDRSLVVRADIAAVLASAV-------------
>tr|G9PLV5|G9PLV5_9ACTO Uncharacterized protein OS=Actinomyces sp. oral taxon 849 str. F0330 GN=HMPREF0975_01376 PE=4 SV=1
------------------------------RRLADAASQADAVVLGAGSGLSAAAGLS-FTRLPDFIEEFGLTDMYSSGFYPPTPEHRWAYWSRHIMANR
-YNEPILPLYQDLRTILDSGDTGYFVITTNVDHAFVRNGFDRLFATQGDYGLWQCSVCHATWSNESPSSLLPVCPKCG--EPAAMNLRVDGTFVEVADRY
RRFLSDRVLYLEIGVGWNT-PSIKFPFWQYNTSAVFATLNQ-EPEVPRQRSIAVPGDIAASIEAWK-------------
>tr|F3P8Q1|F3P8Q1_9ACTO Uncharacterized protein OS=Actinomyces sp. oral taxon 170 str. F0386 GN=HMPREF9056_01421 PE=4 SV=1
--------------------------------------------------MSAAAGLS-FARLPDFIEEFGLSDMYSSGFYPPTPEHRWAYWSRHIMANR
-YDNPILPLYQDLRAILNGVDTDYFVITTNVDHAFARNGFDLLFATQGDYGLWQCSVCHATWSNESPSSSLPTCPRCG--EPAAMNLRVDSTFVEAAERY
HRFLSDRVLYLEIGVGWNT-PSIKFPFWQYNSSATFATLNQ-EPEVPQQRSIAVPGDIAASIEAWK-------------
>tr|A0A078M6C9|A0A078M6C9_9STAP Uncharacterized protein OS=Jeotgalicoccus sp. 13MG44_air GN=BN1048_01163 PE=4 SV=1
------------------------------GRLSMALDEADAVLIGVGAGMAAADGFT-FTESPDFIEKYCWLDMFQASVFDETLNEEWAFFSRFVDLNY
-MSQPLGESYVRLNELLE--GKNYHIITSNADNAFEIAGFNRVFDVQGKYNLLQCSQCTQRYNNEAPDDLIPYCGECG--APMELNRRNTDWMVEDQKLF
NNFLNKKILLLELGCGYMA-PQIKHPFQKERSNALYMTVNLKDYSMPHDRLVWLQEDIKKLLSDVE-------------
>tr|E0QGT8|E0QGT8_9FIRM Uncharacterized protein OS=[Eubacterium] yurii subsp. margaretiae ATCC 43715 GN=HMPREF0379_0236 PE=4 SV=1
------------------------------IKIRKIINEADAIVIGAGAGLSTSAGFS-FDKYRDFVDKYGFSDMYSGGFFPTSVEEKWAYWSRYVYINR
-YSPVPNDTYAKLFELIR--DKNYFVITTNVDHCFQKSGFDRLFYTQGDYGLFQCSRCHKTYENYGDSKLIPRCPICG--EYMSMNLRSDDTFVESAKRY
AEFISKKIVFMELGVGMNT-PGIKYNFWNRFEKANYICINYDDATYPSEKSISIEGDLDEIIERLG-------------
>tr|R7FPG7|R7FPG7_9CLOT Uncharacterized protein OS=Clostridium sp. CAG:288 GN=BN588_00734 PE=4 SV=1
------------------------------EVLKKHIDDAEVIVIGAGAGLSSAAGFE-FLKYKYMHDMYGYTDMYSAGFHNKSPEEKWAYWSKMIYVNR
-YKVGPTKLYKHLLNIIK--NKNYFVITTNVDHQFQLSGFDRLFYTQGDYGLFQCSKCHNTYDNKEPTKLVPKCPVCG--SLMETNLRKDNYFVEALNRY
EKFLEKKILFLEIGVGWNT-PGIKFPFMQYFKNAFYISINNDPSDIPNDKAIHIKEDLNILLKL---------------
>tr|E3GM87|E3GM87_EUBLK Uncharacterized protein OS=Eubacterium limosum (strain KIST612) GN=ELI_1729 PE=4 SV=1
------------------------------RWLKKAIETAEAVLIGAGAGLSSSAGMT-FKWLPDFIRAYHFPDMYSAGFYPDTPEEHWGYWSRYIYHNR
-YEENDRKPYEILLGLVG--HKDYFVLTTNVDHQFQLSGFDRLFYTQGDYGLWQCSRCCDTWDNEAPSAFLPHCPVCG--APMTMNLRCDNNFVQAHSRY
EDFFSSRLLLLELGVGGKT-PVIKYPFWQANPRAAFACINLGEAVCPQKQSVCIDGDIGKVLL----------------
>tr|F3AK45|F3AK45_9FIRM Uncharacterized protein OS=Lachnospiraceae bacterium 9_1_43BFAA GN=HMPREF0987_00819 PE=4 SV=1
------------------------------NRLKNEIKNADAIVIGAGAGMSTSAGLT-FEKYPDFHKKYGISDMYSGGFYPETLEEYWAWWSRHIYINR
-YDITAGKPYMDLLNIVK--DKDYFVLTTNVDHQFQLAGFDRLFYTQGDYGLWQCSRCHDTYDNEEPSDLIPKCPVCG--APMTMNLRCDNSFVQAASRY
EDFIESHLLFLELGVGSNT-PVIKYPFWQANPKAIYACVNHGEAYCPQKQSICFDMDIAEMLENVR-------------
>tr|W1Q6J5|W1Q6J5_ABIDE Uncharacterized protein OS=Abiotrophia defectiva ATCC 49176 GN=GCWU000182_000086 PE=4 SV=1
------------------------------QQLLALLKEAQAVVVGIGAGMSAADGFT-FQEAPDFIEKYGFLDMLQASLFDPSWSEYWAFQSRFVCLNY
-LDQPVGPSYLALKDLLK--DKDYHIITTNADNAFWVADYDKVFHIQGEYGLMQCSRCHATYRDHAAYEDIPLCPKCG--APLEINKRNEKGMVEQLGRY
KDFLGDKVLYLEIGVGFTT-PQIKQPFHQMNPDALLVTLNQKQYRMPRDRTVWLSQDSKDLLLACV-------------
>tr|G5K2Y7|G5K2Y7_9STRE Uncharacterized protein OS=Streptococcus ictaluri 707-05 GN=STRIC_1155 PE=4 SV=1
------------------------------EQLAQLIAEADVLVIGIGAGMSAADGFT-FENTPDFIEKYKLLDMLQASLYDEDWQEYCAFQSRFVALNY
-LDQPVGQSYLDLLDMIK--NKAYHIITTNADNAFWAAHYDKIFHIQGEYGLWQCSQCHQTYKNDEPAELIPLCPKCG--EPFEINKRNEKGMVEQKERY
EAFLTGKVLYIEIGVGHTT-PQIKHPFWKANPDALLVTLNHKHYRMPLQQSLELTQHISQLIAETK-------------
>tr|A0A0P7J3N9|A0A0P7J3N9_9BACI Deacetylase SIR2 OS=Lentibacillus amyloliquefaciens GN=AOX59_01605 PE=4 SV=1
------------------------------DLLNQLIDEAEAIVIGIGAGMSAAAGFT-FTDAPDFIAKYRFLDMLQASLFDEDEQEYWAFQSRFSLLNF
-FDQPVGQAYVDLRLIMA--GNNYHVITTNADNAFYAAKFDKVFRIQGEYGLWQCSECHQTYHDEVPANLVPHCPKCG--AGLEINKRNEKGMVEQNERY
GQFLDKKILFLEIGVGHTT-PQIKHPFQQENAKALFVTMNQKDYFIPHPQTVRIDADIAEV---LH-------------
>tr|A0A0A3HPK9|A0A0A3HPK9_9STRE Deacetylase SIR2 OS=Streptococcus phocae subsp. salmonis GN=NX86_01985 PE=4 SV=1
------------------------------EQLAQLLTEADAVVVGIGAGMSAADGFT-FEEAPDFILKYQFLDMLQASLFQEDWEEYWAFQSRFVALNY
-LDQPVGQSYVDLLQILS--TKPYHIITTNADNAFWAAGYHTVFHIQGEYGLWQCSQCHQTYKDDNPSHLIPYCPKCG--APFEINKRNEKGMVEQHKRY
EDFLKDKVLYLEIGVGHTT-PQIKHPFWKMNPNALFVSLNHKHYRIPKPQSLELTQDISSLIHQTN-------------
>tr|G7SIZ9|G7SIZ9_STRSU SIR2 family protein OS=Streptococcus suis ST1 GN=SSUST1_0306 PE=4 SV=1
------------------------------ELLAGLLAEADAVVVGIGAGMSAADGFT-FEVAPDFIAKYGFLDMLQASLFDESTEEYWAFQSRFVALNY
-LDQPVGASYIHLREILE--TKPYHIITTNADNAFWVADYDKVFHIQGEYGLWQCSRCHDTYRDDAPYDLIPRCPVCD--APFEINKRNEKGMVEQKARY
DAFLTGKVLYLEIGIGFTT-PQIKTPFQTQNSHALYVCLNQKHYRLPLERSLTLAEDSAQLLKETH-------------
>tr|C7N881|C7N881_SLAHD Uncharacterized protein OS=Slackia heliotrinireducens (strain ATCC 29202 / DSM 20476 / NCTC 11029 / RHS 1) GN=Shel_21050 PE=4 S
------------------------------ERLACALEEADAVAIGAGAGLSTSAGMV-FHTYDDFETKYGFTDMYSGGFTRETPEEQWAFWSRMIAMNR
-LVKAPGTAYTDLFELVK--DKDYFVITTNVDHQFQLSGFDRLFYTQGDYGLLQCPLCHRTYENEDPTDLLPTCPKCG--RPMAMNLRIDDTFVEASKRY
ADYLSGKVVYLELGVGMNT-PGIKYPFWRGNKHATFACINLGMAAAPEDQCILIDADIQQTLAKLL-------------
>tr|K9CJZ5|K9CJZ5_9FIRM Uncharacterized protein OS=Selenomonas sp. F0473 GN=HMPREF9161_01230 PE=4 SV=1
------------------------------KALEKSLADAETILVGAGAGLSAAAGYD-FLKYSDFHTTFGIEDIYSGGFYPPSRELYWGWWSRSIYVNR
-YAPLPRDTYARLLSLVR--ERDYFVLTTNVDHAFQRARFDRLFYTQGDFGLFQSSAAAGTYDNEGPTALIPYCPDDG--REMTTNLRADESFVEAAARY
RDFLGRRTLLLELGVGMNT-PGVKYPFWRARTGVTLASVNLGMRYVPPPQSIVIDGDIDAVLRIVS-------------
>tr|G5H2R5|G5H2R5_9FIRM Uncharacterized protein OS=Selenomonas noxia F0398 GN=HMPREF9432_01212 PE=4 SV=1
------------------------------AKLKNALASAECILIGAGAGLSSAAGYD-FLKYSDFHERFGIEDIYTGGFYPPTRGLFWAWWSRSIYINR
-YAPMPEDVYPNLLRLAA--GRDYFVLTTNVDHAFQRTGFDRLFYTQGDFGLFQSSRAAGTYDNEKPAYLIPYCPDDG--TEMTTNLRVDASFVEAATRY
EDWLGRRMLLLELGVGANT-PDIKYPFWRARADVTLAAINLG-AYVPDGRSIALDGNLEEVLRELL-------------
>tr|A0A0K1FGD8|A0A0K1FGD8_9FIRM Sir2 silent information regulator family NAD-dependent deacetylase OS=Selenomonas sp. oral taxon 478 GN=ADJ74_04275 PE=4 SV=1
------------------------------TRITDALRAADCVLIGAGAGLSTSAGYD-FMTYADFHERFGMTDIYSGGFYPPSREIFWAWWSRSIYVNR
-YAPMPEDVYPNLLHLVR--EKDYFVLTTNVDHAFQRTGFDRLFYTQGDYGLFQSSQAAHTYDNEDPTELIPRCPDDG--AEMTTNLRADSSFVEAAARY
TDYLGRRTLLLELGVGMNT-PGIKYPFWRARADVTLVTVSRD-AYVPKDRSVVLGSDIGAVLRELV-------------
>tr|L1N2S4|L1N2S4_9FIRM Uncharacterized protein OS=Selenomonas sp. oral taxon 138 str. F0429 GN=HMPREF9163_01266 PE=4 SV=1
-------------------------------KLKNALASAECILIGAGAGLSTAAGYD-FLKYSDFHARFGIEDIYSGGFYPPTREMFWAWWSRSIYINR
-YAPLPGDVYGNLLHLVA--GRDYFVLTTNVDHAFQRVGFERLFYTQGDFGLFQSSTHARTYDNEEPTALIPYCPDDG--AEMTTNLRADASFVEAAARY
TDYLGKRTLLLELGVGMNT-PGIKYPFWRARTDVTFATVNLGMGYVPPAQSIVIDSDIAEVLRLMA-------------
>tr|G5GNB6|G5GNB6_9FIRM Uncharacterized protein OS=Selenomonas infelix ATCC 43532 GN=HMPREF9334_00870 PE=4 SV=1
-------------------------------QLKNALASADCILIGAGAGLSAAAGYD-FLKYSDFHTRFGIEDIYSGGFYPPSREMFWAWWSRSIWINR
-YAPMPADVYPNLLHLVE--GRDYFVLTTNVDHAFQCSGAARIFYMQGDYGLFQSSRTAGTYDNEEPSDLIPYCPDDG--MEMMTNLRADASFVEAAARY
TDYLGRRTLLLELGVGMNT-PGIKYPFWRARADVTFAAVNLGIEYVPPPQSIVIDGDIAKTLRMLA-------------
>tr|F5RJW2|F5RJW2_9FIRM SIR2 family protein OS=Centipeda periodontii DSM 2778 GN=HMPREF9081_0533 PE=4 SV=1
------------------------------RTIQKRPLLCRLHSDRRGGGLSAAAGYD-FLKYSDFHERFGIEDIYSGGFHPPAREMFWAWWSRSIYINR
-YAPLPGDVYADLLRLVR--GRDYFVLTTNVDHAFQRAGFDRLFYTQGDYGLFQSSKAAGTYDNEEPTDLIPYCPDDG--AEMTTNLRADERFVEAAERY
TDFLGKRTLLIELGVGMNT-PGIKYPFWRARTDVTLVSINLGRAYVPDERSIVIDGDIAEVLRDIA-------------
>tr|E7N4S9|E7N4S9_9FIRM Uncharacterized protein OS=Selenomonas artemidis F0399 GN=HMPREF9555_02024 PE=4 SV=1
------------------------------NALKKALADAETILIGAGAGLSTAAGYD-FLKYSDFHAAFGIEDIYSGGFYPPSRELYWGWWSRSIYINR
-YVPLSGDTYARLRSLVR--GRDYFVLTTNVDHAFRRAGFDRLFYTQGDFGLFQSSKQAGTYDNEEPTELIPHCIDDG--REMTTNLRVDSSFVEAARRY
EDFLGKKTLLLELGVGMNT-PGIKIPFWQARADVTLATVNLGAPYVPSARSIVIDADIDEVLCAAY-------------
>tr|E6MBK6|E6MBK6_STALU Uncharacterized protein OS=Staphylococcus lugdunensis M23590 GN=HMPREF0790_1809 PE=4 SV=1
------------------------------DILLRAIYEADAVVVGIGAGMSAADGFT-FTQNPDFIEKYGFFDMLQASLHPDSWQEYWAFESRFVVLNY
-LDQPVGASYLALKSLLA--QKAYHIITTNADNAFLAADYDKVFHIQGEYILWQCSQCHATYRDDDPWTLIPHCPKCD--APMEINKRKQVGMVEQLERY
NAFLHGKVLYLEIGIGYTT-PQVKHPFQRRNPDALFMTLNKKAYRIPQARTIHLNEDIATLMTTAQ-------------
>tr|A0A0M2P4W9|A0A0M2P4W9_STACC NAD-dependent protein deacetylase of SIR2 family OS=Staphylococcus cohnii subsp. cohnii GN=UF66_1232 PE=4 SV=1
------------------------------DVLAQAIDEADAVVVGIGAGMSASDGFT-FTQNPDFIEKYGFFDMLQASLHTESWQEYWAFQSRFVALNY
-LDQPVGASYVALKEILK--NKAHHIITTNADNAFAVAGYDKVFHIQGEYILWQCSQCHPTYRDDEPRELVPHCPKCD--APMEINKRKQVGMVEQLSRY
NQFLEGKVLYLEIGIGYTT-PQVKHPFQRRNPDALFMTLNKKAYRIPQERTIHLTDDISTLVLEAN-------------
>tr|A0A0Q9XJB6|A0A0Q9XJB6_9STAP Deacetylase SIR2 OS=Staphylococcus sp. NAM3COL9 GN=ACA31_12150 PE=4 SV=1
------------------------------DILADALNEADAVVVGIGAGMSASDGFT-FTQNPDFIKKYGFFDMLQASLHTESWQEYWAFQSRFVALNY
-LDQPVGASYSALNQILS--NKDYHIITTNADNAFAVAGFDKVFHIQGEYILWQCSQCHATYRDDAPRERLPHCPECD--APMEINKRKQVGMVEQLSRY
NQFLEDKVLYLEIGIGYTT-PQVKQPFQRRNPNALFMTMNKKAYRIPEDRTIHLTEDISTLMIEAN-------------
>tr|D4YF21|D4YF21_9LACT Uncharacterized protein OS=Aerococcus viridans ATCC 11563 GN=HMPREF0061_0460 PE=4 SV=1
------------------------------KMLQEAVAEADAVVVGIGAGMSAADGFT-FENNPDFIEKYGFFDMLQASLFDPSTQEYWAFESRFITLNY
-LDQPVGASYIALKELLA--NKPHHIITTNADNAFAVADYDRVFHIQGEYILMQCSQCHQTYRDDDPYDLIPHCPECG--AVMEVNKRKGKGMVEQKARY
DDFLGQAILFLDIGVGYTT-PQVKTPFQEANPKAMYVQLNKKLYRIPDGQTYRLDGDIADTIIGAN-------------
>tr|A0A068E3X7|A0A068E3X7_STAXY NAD-dependent protein deacetylase of SIR2 family OS=Staphylococcus xylosus GN=SXYLSMQ121_0194 PE=4 SV=1
------------------------------DQLADALQEAEAIVVGVGAGMSAADGFT-FTQHPDFIAKYGFFDMLQASLHPESWQEYWAFESRFVVLNY
-LDQPVGASYVALKQILE--AKDYHIITTNADNAFAVADYDKVFHIQGEYILWQCSQCHATYRDDDPRALVPHCPKCD--APMEINKRKQVGMVEQLLRY
NQFLEAKVLYLEIGIGYTT-PQVKHPFQRKNPNALFMTLNKKAYRIPVERTIHLTDDISTLILEAN-------------
>tr|A0A0M2NJT8|A0A0M2NJT8_9STAP NAD-dependent protein deacetylase of SIR2 family OS=Staphylococcus pasteuri GN=UF70_2019 PE=4 SV=1
------------------------------SILAQAIDEADAVVIGIGAGMSASDGFT-FTSNPDFIEKYNFFDMLQASLYPGSWQEYWAFESRFVKLNY
-LDQPVGASYVALKNILK--DKDYHIITTNADNAFLVANYDKVFHIQGEYILWQCSQCHATYRDDDPWELIPHCPKCD--APMEINKRKEVGMVEQLDRY
NAFLTGKVLYLEIGIGYTT-PQVKHPFQRRNPDAIFMTLNKKAYRIPNDKTIHLTEDISTLITDAQ-------------
>tr|A0A069G0L7|A0A069G0L7_STAAU Putative N-acetyltransferase YedL OS=Staphylococcus aureus subsp. aureus CO-98 GN=CO98_1311 PE=4 SV=1
------------------------------DILAQAIDEADAIVVGIGAGMSASDGFT-FTQNPDFIEKYNFFDMLQASLHPDSWQEYWAFESRFVKLNY
-LDQPVGPSYVALKKMLE--HKDYHIITTNADNAFLVADYDKVFHIQGEYILWQCSQCHATYRDDDPYELIPHCPKCD--APMEINKRKQVGMVEQLDRY
NHFLNGKVLYLEIGIGYTT-PQVKHPFQRRNPNAVFMTLNKKAYRIPKDRTIHLTEDIASLIINAQ-------------
>tr|W4N7L5|W4N7L5_9BIFI Transcriptional regulator, Sir2 family OS=Bifidobacterium moukalabense DSM 27321 GN=BMOU_1352 PE=4 SV=1
------------------------------TALAQAWKAADCILIGAGSGLSTSAGYT-FDCLADFKARYGITDMYSGGFHPGTLEEYWAWWSREIYYNR
-YIPAPKPVHERLLDMLRRAAKDYFVLTTNVDHCFQHAGFDRLFYTQGDYGLWQCSLCSQTYDNEEPSELIPHCPRCG--RPMTMNLRADGTFVEAARRY
SDYVDSRILLLELGVGGNT-PGIKYPFWQDNPQATYACLNLGEAVAPRDRSICINADIDATL---T-------------
>tr|C9LYS2|C9LYS2_SELS3 Uncharacterized protein OS=Selenomonas sputigena (strain ATCC 35185 / DSM 20758 / VPI D19B-28) GN=SELSPUOL_02633 PE=4 SV=1
------------------------------ERLRQALFEAEAVVVGAGAGLSVAAGYL-FQKHADFIERYHFRNMYEGGFYPPTLEEKWAYWSRYIWINR
-YEERQNALYQRLLSVLC--SKDFFVITTNVDHFFQDNGFPRLFYTQGDYGLWQCSVCHDTYDNYDPRELVPHCPRCG--EPMGMNLRADSTFVEAAKRY
QEFLTGRVLYWEFGVGANT-PGIKYPFWAKNPAAVYCVMNQGEAVAPQAQSILVDGDIDASLKALQ-------------
>tr|S3AMI0|S3AMI0_9ACTN Uncharacterized protein OS=Atopobium sp. oral taxon 199 str. F0494 GN=HMPREF1527_01462 PE=4 SV=1
------------------------------ECLREAISKADALVVGAGAGLSTSAGFT-FERYGAYEEAYGFHDMYSGGFYPRSLEEYWGYWCKHIWYNR
-YVPAPKDTYKKLLRLLP--GRDFFALTTNVDHQFQLAGFPQLFYTQGDYGLWQCSICHKTYDNYDASELVPRCPVCG--EPMTMNLRSDATFVEASRRY
GRFIHDRTLYLELGVGGNT-PGIKYPFWRHNPQATYACINFGEVFAPKEQSILIDADIDIVLNDLL-------------
>tr|A0A087CQ53|A0A087CQ53_9BIFI Putative SIR2 family protein OS=Bifidobacterium ruminantium GN=BRUM_1768 PE=4 SV=1
------------------------------ERFAKAWREADCVLVGAGSGLSTSAGYT-FDRLSDFKERYGIADMYSGGFYPDTLEEYWAWWSRAIYYNR
-YVPAPKPVHHMLLNMLRSGKDEYFVLTTNVDHCFQKAGFDRLFYTQGDYGLWQCSLCAQTYDNERPSDLVPHCPRCG--RPMMPNLRCDASFVEAARRY
GDFLNSRILLLELGVGGNT-PAIKYPFWRGNPNATYACLNLGEAAAPANRSICVNADIFATL---G-------------
>tr|G5F2W0|G5F2W0_9ACTN Uncharacterized protein OS=Olsenella sp. oral taxon 809 str. F0356 GN=HMPREF1008_00704 PE=4 SV=1
------------------------------GELARRIREADAVLVGAGAGLSAACGPEFFLARGDFHERFGITDLYSGGFYPPGATTRWAWWSRHVWYAR
-YDCPVGEPYRDLVALLR--GREHFVLTTNVDHQFQRAGVDRLFYTQGDYGLWQCSVCHDTYDNYEPEELVPRCPRCG--EEMSMNLRADSTFVEAAGRY
RAFLGDKVVYLEVGVGNNT-PGIKYPFWKANPRATYAQVNATESLAPAERAILIRDDAARVLAGLR-------------
>tr|A0A077UG39|A0A077UG39_9STAP SIR2 family protein OS=Staphylococcus schweitzeri GN=ERS140147_00418 PE=4 SV=1
------------------------------EVLRTAIDEADAIVIGIGAGMSASDGFT-FTENPDFIEKYRFFDMLQASLHPGSWQEYWAFESRFIKLNY
-LDQPVGQSYLALKSLME--GKQYHIITTNADNAFDVADYDHVFHIQGEYILQQCSQCHATYRNDEPWEMIPRCPKCD--APMEVNKRKEVGMVEQLQRY
NAFLDDKVLYLEIGIGYTT-PQVKHPFQRRNENALYMTMNKKAYRIPNERTIHLTDDISSLITTAL-------------
>tr|G5JHK1|G5JHK1_9STAP Uncharacterized protein OS=Staphylococcus simiae CCM 7213 GN=SS7213T_04666 PE=4 SV=1
------------------------------GVLAQAINEADAVVIGIGAGMSAADGFT-FTNHQDFIAKYNFFDMLQASLYPGSWQEYWAFESRFIQLNY
-LDQPVGESYIALKQMMS--TKDYHIITTNADNAFWAADYDHVFHIQGEYILQQCSQCHATYRNDDPWELIPHCPKCD--APMEVNKRKEVGMVEQLERY
NAFLQGKVLYLEIGIGYTT-PQVKHPFQRRNTNALYMTLNKKAYRLPQSRTIHLTEDIRHLITEAQ-------------
>tr|R6KFZ3|R6KFZ3_9FIRM SIR2 family protein OS=Eubacterium sp. CAG:252 GN=BN564_00423 PE=4 SV=1
------------------------------KKLEELLNKSDTIVIGAGAGLSTSAGFT-FEDNSDFIEKYGFKDMYSGGFYPESLEEHWAYWSRYIYINR
-YMDVDNGTYKRLFELVK--NKDYFVLTTNVDHQFQKAGFDRLFYTQGDYGLFQCSECSDTYDNEDPSKLIPYCPVCG--KPMSMNLRADDTFVQAGGRY
SDFMKDRVLFLELGVGMNT-PGVKYNFWNYNPDASYVCINYGEAFAPKDRALCIDGDICEVLSAIH-------------
>tr|C6LDJ6|C6LDJ6_9FIRM Uncharacterized protein OS=Marvinbryantia formatexigens DSM 14469 GN=BRYFOR_06605 PE=4 SV=1
------------------------------RRIKELLQNADAVIIGAGAGLSTSAGFT-FEENPDFIKKYGIRDMYSGGFYPESPEEYWAYWSRYVFINR
-YLDRDNGTYERLYGLVK--DKDYFVLTTNVDHQFQKAGFDRLFYTQGDYGLFQCSVCHNTYDNEKPTELIPRCPVCG--KPMTMNLRADSTFVQAGERY
SDFLGLKMLLLELGVGMNT-PGIKYPFWQANKEAVYVCINKGQAYAPKDRSICINGDIGEILQQL--------------
>tr|E6UCV8|E6UCV8_RUMA7 Uncharacterized protein OS=Ruminococcus albus (strain ATCC 27210 / DSM 20455 / JCM 14654 / NCDO 2250 / 7) GN=Rumal_2304 PE=4 SV
------------------------------DRLKKEIQTADAIVIGAGAGLSTAAGFT-LQKYADFVEKYGFRDMYSGGFYPETSEEMWAYWSRYIYINR
-YMDVDNGTYKRLFELVK--DKDYFVLTTNVDHQFQKAGFDRLFYTQGDYGLWQCSECHQTYDNEEPSELVPHCPVCG--KPMSMNLRADDTFVEAAERY
DEFLGLHILFLELGVGMNT-PVIKYPFWKYNPKAVYACLNFGEAYAPDEQSILINGDIHELLNVLA-------------
>tr|J9UUC1|J9UUC1_BRAPL SIR2 family protein OS=Brachyspira pilosicoli B2904 GN=B2904_orf1529 PE=4 SV=1
------------------------------EKLKLAIEESDYILIGAGAGLSASAGFL-FDDNSEYREKYGLTDMYSAGFYNPTLEDFWGFFSLFVYINR
-YDIPADETHLNLLDIVK--NKNYFVITTNVDGRFEAANFDRLFKVQGDFSLFQCSICKQTFYNEKPSELIPKCPYCK--ANMSMNLRSDDTFVQAKDKY
KAFLDKNILFLELGVGFNT-PGIKYSFWRLNKNSIYASINLKNVFSIPERSICIDDDISKVLKYIK-------------
>tr|B9Y347|B9Y347_9FIRM Uncharacterized protein OS=Holdemania filiformis DSM 12042 GN=HOLDEFILI_00222 PE=4 SV=1
------------------------------AALRKALKEAQAVVIGAGAGLSISAGFS-FYEHQDFADAYGFQDMYSGGFYPDTLEEYWAYWSRYIELNR
-YSPARYPVYERLLELVQ--GKDYFVITTNVDHQFQRAGFDRLFYMQGDYGLWQCSVCHQTYDNEAPSRLIPRCPRCG--KPMSMNLRIDATFVEAARRY
GDFLHKKILFLELGVGLNT-PGIKYPFWQTNPQAMYACLNLGEVYAPEERSICLSVNIRDFYLTSS-------------
>tr|R9MTS5|R9MTS5_9FIRM Uncharacterized protein OS=Lachnospiraceae bacterium 3-2 GN=C818_01190 PE=4 SV=1
------------------------------QSLRLALNGADAVLIGAGAGLSASAGFI-FQKYKDFALKYGFRDMYSGGFYPESLEEHWAYWSRYIFINR
-YMAPPKPGYQKLYELIQ--NKDYFVLTTNVDHCFQNAGFDRLFYTQGDYGLFQCSKCCQTYDNESPPELVPHCPVCG--RPMSMNLRADSTFVEATGRY
KDFLSQKMLILELGVGMNT-PGIKYPFWRANPKAIYACVNFGETYVPEKRSVCINADIGEILKH---------------
>tr|I0R4A8|I0R4A8_9FIRM Uncharacterized protein OS=Lachnoanaerobaculum saburreum F0468 GN=HMPREF9970_0853 PE=4 SV=1
------------------------------QRLKDELRSCDAVLIGAGAGLSTSAGLT-FEKYFDFSKAFGIKDMYSGGFYPPKKEIFWAWWSRHIYFNR
-YIDTPKPVYKDLLELVK--DKDYFVITTNVDHRFQMAGFDRLFYTQGDFGLFQSMDNCKTYDNKTPSEFIPKTPE-G--FDVTTNLRADNSFVEASSNY
ADFLNLHILFLELGVGANT-PVIKYPFWQYNKNSIYACLNLKEAFCPESRSICIDGDIGEALK----------------
>tr|A0A0F0CI88|A0A0F0CI88_9CLOT Uncharacterized protein OS=Clostridium sp. FS41 GN=CLFS41_14480 PE=4 SV=1
------------------------------QRAASMISKADAVLVGAGAGLSAAAGLT-FKENSEFIGRYGMRDMYAAGFYPPTEEERWGYWSKHVWVNR
-IEPGALPLYRKLCDMVT--TRKHFVLTTNVDHQFWKAGFENIFATQGDYGKIQCAGCHDTYDATDPSCMVPVCPVCG--GPMAMNLRCDQYFVEAAKRY
SAFLLKETVVLELGVGFNT-PAIRFPFEKRNGRWSFIRLNTDGAAVPAKRAAGINGDMTESLEGIC-------------
>tr|G5IFB1|G5IFB1_9CLOT Uncharacterized protein OS=Hungatella hathewayi WAL-18680 GN=HMPREF9473_02188 PE=4 SV=1
------------------------------QRAARWLKEADAVLIGAGAGLSTAAGLN-FTENGEFIERYGMPDMYAAGFYPPTEEERWGYWSRHALVNR
-IEPEGLPLYRELHELVK--AKEHFVLTTNVDHQFWKAGFDRIFATQGDYGLIQCQKCHSTYDATEPPSLVPRCPVCN--GPMTMNLRCDQYFVEAAARY
EAFLGKQLVLLECGVGFNT-PVIRFPFEHAHPAWRLIRLNLDEAVVPEHRSAGISMDIARSILDIK-------------
>tr|A5KL84|A5KL84_9FIRM Uncharacterized protein OS=Ruminococcus torques ATCC 27756 GN=RUMTOR_00988 PE=4 SV=1
------------------------------DRAAKNIRNTDCVIIGAGAGASTAAGIQ-FTDNAEFIKKYGMTDMYAAGFYPPSEEAKWGYWSKHALMNR
-FDPPALPLYTELYDLVK--NKEYFVLTTNVDHQFYKAGFDRIFATQGDYGKIQCQKCHSTYDAKDPSELVPKCPVCG--GNMAMNLRCDNYFVEAADRY
AGFLDKKVVLLELGVGFNT-PIIRFPFEKRNSSYSLIRLNMDEAVVPEERAIGIGGDMAKAITDIR-------------
>tr|D6E262|D6E262_9FIRM Uncharacterized protein OS=Eubacterium rectale DSM 17629 GN=EUR_02760 PE=4 SV=1
------------------------------DRAVEYIRNADCILIGAGAGASTAAGIS-FTDNAEFIEKYGMTDMYAAGFYPPTEEAKWGYWSKAALLNR
-FDLPALPLYKELYDIVK--RKEYFVLTTNVDHQFYKAGFDRIFATQGDYGKIQCQKCHPTYDAQEPSELVPKCPVCG--GRMEMNLRCDNYFVEAADRY
ADFLNKKVVLLELGVGFNT-PIIRFPFEKRNSSYSLIRLNMDEAVVPEKRAIGIEGDMERAITDIR-------------
>tr|C5EGG5|C5EGG5_9FIRM Uncharacterized protein OS=Clostridiales bacterium 1_7_47FAA GN=CBFG_01010 PE=4 SV=1
------------------------------RRAAGLLNRADAVLIGAGAGLSTAAGLV-FTENGEFIERYGMRDMYAAGFYPPTEEERWGYWSRHAYVNR
-IEPQALPLYLKVFEMVC--GREHFVLTTNVDHQFWKAGFEDIFATQGDYGLIQCAKCHGTYDATGPSGMVPRCPVCK--GPMAMNLRCDGYFVEAAGRY
GDFLGRRLVLLELGVGFNT-PVIRFPFEKGNREWSLIRLNLDEAAVPEYRAVGINMDLAVCVGDIR-------------
>tr|F7UYI9|F7UYI9_EEGSY NAD-dependent protein deacetylase OS=Eggerthella sp. (strain YY7918) GN=SIR2 PE=4 SV=1
------------------------------DRLHRALCEADAVLIGAGAGMSTAAGLT-FDKNADFRDRFGITDMYSGGFYPPDAETFWAWWSRHIFINR
-YEAKPGKPYRDLFNLVR--DKDYFVITTNVDHQFHLAGFDRLFCTQGDYGLFQCSGCTQTYDNEAPSDLIPRCPHCG--SPLTTNLRIDDRFVQANARY
HAFCDANVLYLELGVGMNT-PVIKYPFWNKNKHATYCCINKGEACAPEERSILLDADIGEVLSNAF-------------
>tr|R5FQ49|R5FQ49_9ACTN NAD-dependent protein deacetylase OS=Eggerthella sp. CAG:1427 GN=BN494_00228 PE=4 SV=1
------------------------------KRLKDKLEEADAILIGAGAGLSTAAGLT-FEKNADFKNTFHITDMYSGGFYSPDLETYWAWWSRHIWINR
-YEPGPTSLYRNLLQIVK--DRNYFVLTTNVDHQFQLAGFDRLFYTQGDYGLFQCSKCTQTYNNEAPTALIPHCPHCG--APLTTNLRVDNSFVEAQNRY
RSFVNKRILFLELGVGGNT-PVIKYPFWQLNPQATYASINLKESFSPRSQSILINADIQKVLLHLL-------------
>tr|A0A0K2RYN7|A0A0K2RYN7_9MICC NAD-dependent protein deacetylase OS=Rothia mucilaginosa GN=RM6536_0435 PE=4 SV=1
------------------------------ERAAKAIQEADLIVIGGGSGFSTAAGHV-FTNNAPYIQKYGMTDMYSAGFYPKSLEEKWGYWARHILFNR
-YETGSLPLYEQLRELVA--DKEYFIVTTNVDSLFEKSGFDRIFEQQGNYGAFQCSRCTQVYDNEEPSELVPMCPRCG--APLTTHLRIDGSFVNQEKRW
EEVLGKKVLLLELGVGFMT-PTIRFPFERHLDTATLVRLNRDYPQATEEKTVSFAEDAH---QVLR-------------
>tr|A0A086ZPF5|A0A086ZPF5_9BIFI NAD-dependent protein deacetylase, SIR2 family OS=Bifidobacterium boum GN=BBOU_0535 PE=4 SV=1
------------------------------SRLKKEIETADAIVIGAGAGLSTSAGMT-FDRYFDFARKYGIQDMYSGGFYPPDAETSWAWWARNIYFNR
-YMDPPRPVYQQLLSLVQ--DKDYFVITTNVDHQFQRAGFDRLFYTQGDYGLFQSVNSTQTYDNEEPAALIPKCPDDG--SDVTMNLRVDGSFVEASAAY
ADFLGRHVLYLELGVGANT-PVVKYPFWQLNEKAVYACINYGEAFCPGGRSICVNGDIGDVFTSLS-------------
>tr|I5AX63|I5AX63_EUBCE Uncharacterized protein OS=[Eubacterium] cellulosolvens 6 GN=EubceDRAFT1_2679 PE=4 SV=1
------------------------------LRLQKEINDADAVVIGAGAGLSTSAGFT-FQKYSDFEEKYGFHDMYSGGFYVRDPEISWAYWARNIYINR
-YMKAPKPVYERLLELVK--EKDYFVITTNVDHQFQKAGFDRLFYTQGDYGLFQSVNAIRTYDNEEPSELIPKCPDDG--SDVAMNMRADDSFVEASAAY
SDFINLHVLYLELGVGANT-PVIKYPFWQLNEKAVYACLNYGESFCSEDRSICIDGDIATILQES--------------
>tr|F7KWU8|F7KWU8_FUSNU SIR2 family protein OS=Fusobacterium nucleatum subsp. animalis 11_3_2 GN=HMPREF0401_00069 PE=4 SV=1
------------------------------KKLKNEIKNADAIIIGAGAGLSTSAGLT-FKKYFDFAEKYGIKDIYSGGFYPPNNETKWAWWARQIYFNR
-YIDPPKPVYRNLLSLLK--DKNYFVITTNVDHQFQRAGFDRLFYTQGDYGLFQSVNEIQTYNNEDPTALIPKCPDDN--SDMTTNLRIDDSFVEASEAY
YNFLNKHILFLELGVGANT-PMIKYPFWQMNEKSIYACINYGEVFCPQDRSICIDGDIGSVLELIK-------------
>tr|H1HUY8|H1HUY8_9FIRM Uncharacterized protein OS=Stomatobaculum longum GN=HMPREF9623_01408 PE=4 SV=1
------------------------------ARLKQEIEMSDAIVIGAGAGLSASAGLT-FERYFDFAKKYGIHDIYTGGFYPPDAETRWAWWARHIYFNR
-YIEPPRPVYRKLLTLVK--DKDYFAITTNVDHQFLRAGFDRLFCTQGDYGLFQTVDRNGTYDNEEPAELIPKCPDDG--ADLTMNLRADDSFAEASAAY
SDFLNLRVLYLELGVGGNT-PVVKYPFWQLNKNAVYACVNYGEAFCPRDRSICIDGDIGEVLELL--------------
>tr|D7N7F7|D7N7F7_9FIRM Uncharacterized protein OS=Peptoniphilus sp. oral taxon 386 str. F0131 GN=HMPREF0629_00747 PE=4 SV=1
------------------------------KILKNEIQNAEAVVVGAGAGLSTSAGMI-FEKYFDFAKKYGIKDMYSGGFYSPDSETKWAWWARNIYFNR
-YVEPPIPVYRKLLSLLE--NKNYFVITTNVDHQFQRAGFDRLFYTQGDFGLFQSINKNQTYDNKNPSSLIPKCPDDN--SDVTMNLRADDSFVEASEKY
YNFLNKHVLFLEFGVGSNT-PVIKYPFWQMNEKAIYACINCGEAFCPQGRSICIDGDIGEVLNDIE-------------
>tr|C4GD69|C4GD69_9FIRM Uncharacterized protein OS=Shuttleworthia satelles DSM 14600 GN=GCWU000342_01914 PE=4 SV=1
------------------------------ARLKQEIKTVDAVVIGSGAGLSTSAGLT-FERYFDFARKYGIRDIYSGGFYPPDDDTRWAWWARHIYFNR
-FIEPPKPVYQELLALVK--DKDWFSITTNVDHQFQRAGFDRLFYTQGDYGLFQTADRNGTYDNEEPAELIPKSPEDG--SDVTMNLRADDSFAEASAAY
SDFLNLHVLYLELGVGANT-PVVKYPFWQLNKNAVYACVNYGEAFCPGDRSICIDGDIGEVLKALL-------------
>tr|F7V4Z7|F7V4Z7_CLOSS NAD-dependent protein deacetylase, SIR2 family OS=Clostridium sp. (strain SY8519) GN=SIR2 PE=4 SV=1
------------------------------SGLKKEIEEADAIVVGAGAGLSTSAGLT-FERYFDFARKYGIQDMYSGGFYPPDEETRWAWWARHIYFNR
-YIDAPKPVYRELLSLVK--DKDYFVVTTNVDHQFQRAGFDRLFYTQGDYGLFQSANSMQTYDNEEPVSLIPKCPDDG--SDVTMNLRADDSFVEASAAY
ADFLNLQVLYLELGVGANT-PVVKYPFWQMNEKAVYVCINYGEAFCPSNRSICIDGDIGDVFAKMK-------------
>tr|G5GK17|G5GK17_9FIRM Uncharacterized protein OS=Johnsonella ignava ATCC 51276 GN=HMPREF9333_01907 PE=4 SV=1
------------------------------KILKNEIQNADAIVVGAGAGLSTSAGFS-FEKYFDFAEKYGMKDIYSGGFYPPDNETRWAWWARHIYFNR
-YIEPPEPVYRKLLSLLK--DKNYFVITTNVDHQFQRAGFDRLFYTQGDYGLFQSVNKIQTYDNEDPTSLIPKCPDDN--SDVTINLRADDSFVEASEEY
YNFLNMHILFLELGVGANT-PVIKYPFWQMNENAVYACINYGEAFCPGGRSICIDGDIGKAINDIM-------------
>tr|I5AXR9|I5AXR9_EUBCE NAD-dependent protein deacetylase, SIR2 family OS=[Eubacterium] cellulosolvens 6 GN=EubceDRAFT1_2908 PE=4 SV=1
------------------------------DRLKEEIGAADAIVVGAGAGLSTSAGFT-FKKWSDFEEKYGFQDMYSGGFYPKTKEGFWAYWSRYIYINR
-YLDAPKDTYSKLYNLVK--DKDYFVITTNVDHCFQKAGFDRLFYTQGDYGLFQSLNAIRNFDNEDDSSLIPKCPIDG--SDVTMNLRSDDTFLEASAAY
SDFLNMQVLFLELGVGSNT-PVIKYPFWQMNDRAVYACLNYGEAFCPGDRSICIDGDIGEVLKQM--------------
>tr|X8ITB4|X8ITB4_9FIRM Uncharacterized protein OS=Mogibacterium timidum ATCC 33093 GN=HMPREF0581_0741 PE=4 SV=1
------------------------------SRLKYELDNADAIVIGAGAGLSTSAGLT-FEKYFDFAKKYDIRDMYSGGFYPPDDETRWAWWARHIYYNR
-YIDAPKQVYQELYEFVK--DKDYFVITTNVDHRFQRAGFDRLFYTQGDYGLFQSVNSLQTYDNEEPTDLIPKCPDDG--SEVTMNLRADDSFVEASAAY
YDFLGLHVLYLELGVGANT-PVVKYPFWQLNEKAVYACINYGEAFCPGNRSICIDADIYEVLRKYA-------------
>tr|A0A086ZQJ5|A0A086ZQJ5_9BIFI NAD-dependent protein deacetylase, SIR2 family OS=Bifidobacterium boum GN=BBOU_0257 PE=4 SV=1
------------------------------TRLTNTIHDADTMVVGAGSGMSTSAGYT-FERYSDFARAYGIGDMYSGGFAEPDLNTYWAWWSRHIYINR
-YMAPPKNTYGLLRSLLD--GHDYTVITTNVDHCFQRAGFPRLFCTQGDYGLFQSSRGTSTYGNERPDGLIPYCPEDG--SPMAPNLRCDDTFAECAERY
QTFLGSRTLFLDLGSGGNT-PIFKFPFMQSNRNAIYTSINLGEAVTAPDRSILIDADIDATLRDIA-------------
>tr|M4RH85|M4RH85_9BIFI NAD-dependent protein deacetylase, SIR2 family OS=Bifidobacterium thermophilum RBL67 GN=D805_1661 PE=4 SV=1
------------------------------TRLTDAIQQADVIVVGAGAGMSTSAGYT-FDRYRDFANTYGISDMYSGGFYDPDLNVMWAWWSRHIYINR
-YMAPSKDTYSLLLNLLD--GRDYTVITTNVDHCFQRAGFPRLFCVQGDLGLYQSSLGTSTYSNERPDELVPYCPDDG--SPMALNLRIDDTFVQCAERY
QSFLGSRTLFLDLGSGGNT-PIFKFPFMQSNRNATYASINLGEAVTAPDRSILIDADIDTTLRNIA-------------
>tr|F7V4K4|F7V4K4_CLOSS Putative uncharacterized protein OS=Clostridium sp. (strain SY8519) GN=CXIVA_17170 PE=4 SV=1
------------------------------ERLRRELETADAVVIGAGAGLSTAAGLT-FNRYFDFAETYGIQDMYSGGFYPPDEETRWAWWARHIYFNR
-YIDPPKSVYHQLLSLVN--EKDYFVITTNVDHQFQRAGFGRLFYTQGDYGLFQQEDSLQTYDNRDPTELIPACPDDG--SAVTMNLRADDTFVEASAAY
AEFLSRHVLFLELGVGANT-PVIKYPFWAANPRAFYACVNRGEAYCPRERSVCIDGNIEEVLQKMF-------------
>tr|F5T3Z8|F5T3Z8_9FIRM Uncharacterized protein OS=Oribacterium sp. oral taxon 108 str. F0425 GN=HMPREF9124_1697 PE=4 SV=1
------------------------------LNLKEKIQNAEAIVLGAGSGLSTAAGFT-FQKYFDFAKKYPIQDMYSGGFFPESPEEFWAWWSRNIYFNR
-YIDIHSDVYGNLKKIVE--GKDYFVLTTNVDHQFQKAGFERLFYTQGDFGLFQSTRTVATYDNREPTELIPICPDDG--LPMTMNLRIDETFVEAAKRY
QDFLRKHVLYWELGVGMNT-PVIKFPFWRENPNAYYACLNLGEAGCSEERSICLNADIAKVLRDLL-------------
>tr|G9WT79|G9WT79_9FIRM Uncharacterized protein OS=Oribacterium asaccharolyticum ACB7 GN=HMPREF9624_00113 PE=4 SV=1
------------------------------RKLKEKIQNAEAIVLGAGSGLSTAAGLT-FHKYFDFAKKYPIQDIYSGGFFPESPEGFWAWWSRHIYFNR
-YVDAPSDVYGNLKKIVE--GKDYFVLTTNVDHQFQRAGFERLFYTQGDYGLFQSSRTLATYDNQEPTDLIPICPDDG--LPMAMNLRVDENFVEAAKRY
QDFLGKHVLYWELGVGMNT-PVIKFPFWRDNPNAYYACLNLGEAGCSRDRSICLNADIGQVLRDLL-------------
>tr|U2R8Q9|U2R8Q9_9FUSO Uncharacterized protein OS=Leptotrichia wadei F0279 GN=HMPREF9015_01237 PE=4 SV=1
------------------------------ELLKNEIQNADAILVGAGSGLSTSAGFT-FEKYFDFIKEYGITDMYSGGFYPPNDEIRWAWWARHIYFNR
-YVKAPKPVYDELFSLLK--DKDYFVITTNVDHQFQKAGFDRLFYTQGDYGLFQSVNQIQTYDNEEPAELIPKCPDDG--SDMTTNLRADSSFVEASEEY
SNYLNMHILFLELGVGRNT-PVVKYPFWYMNKKAVYACINYREAFCPIDRSICLDGDIGEVLGEIY-------------
>tr|E6MJH7|E6MJH7_9FIRM Uncharacterized protein OS=Pseudoramibacter alactolyticus ATCC 23263 GN=HMP0721_2162 PE=4 SV=1
-----------------------------------MLDAADAVVIGAGSGLSTAAGFN-FHKYQDFIDKYGIRDMYSGGFYPPSAEIQWAWWSRHIWLNR
-YVKAPKPVYSELLDRVK--DMDYFVLTTNVDHQFQQAGFNRLFYTQGDYGLFQCSKCHNTYDNKEPEKLVPRCPVCK--EEMTVNLRCDDSFVEAADCY
SEFINSNIVYLELGVGMNT-PVIKYPFWQANLKAYYVCLNLNEAYVPDDRSISIDGDILDVIKKL--------------
>tr|G0VMK3|G0VMK3_MEGEL Uncharacterized protein OS=Megasphaera elsdenii DSM 20460 GN=MELS_2178 PE=4 SV=1
------------------------------QQLQRALHDSAAVVIGAGSGLSTAAGLT-FRRYSDFIRKYGIRDMYSGGFFHSDVREYWAWWSRAIYINR
-YVPAPTDVYRRLYDLVR--DKDYFVLTTNVDHQFQKARFDRLFYTQGDYGLFQEKYVTATYDNEAPAALWPRSPEDG--QDLVPNLRCDDTFVEAARRY
QQFLQGRVLYLELGVGMNT-PGIKIPFWQQNPQAIYACVNASDARSPERQAIGIEGDIADVLTALE-------------
>tr|D4J1Z0|D4J1Z0_BUTFI Uncharacterized protein OS=Butyrivibrio fibrisolvens 16/4 GN=CIY_13210 PE=4 SV=1
------------------------------KRLLQEIKEADAIVIGADAGLSTSAGLT-FEKYYDFAKRFGIRDIYSGGFYPPSEEIRWAWWARHIYFNR
-YIDAPKPVYRDLLKMVS--DKDYFVITTNVDHQFQRAGFDRLFYTQGDYGLFQSVNAIQTFDNEKPSELIPKCPDDG--SDMTMNLRADDSFVEASAAY
SDFINLHVLYLELGVGANT-PVIKYPFWQLNEKAVYACLNYGESFCPEDRSICIDGDIATILQEFG-------------
>tr|G9X034|G9X034_9FIRM Uncharacterized protein OS=Peptostreptococcaceae bacterium ACC19a GN=HMPREF9629_01785 PE=4 SV=1
------------------------------LRLKSELTSADAIVIGAGSGLSTSAGFT-FEKYFDFAKKYGINDMYSGGFYPEDVQTRWAWWARHIYFNR
-YVKTPKPVYDKLFSLIK--DKDYFVITTNVDHQFQKAGFDRLFYTQGDYGLFQSVNDIKTYDNEDPIELIPKCPDDG--LDMTLNLRADDSFVEAYERY
NEFLKMHTLYLELGVGANT-PVVKYLFWQNNEKAVYACINYGEAFCPRDRSICIDGDIGEILNKIV-------------
>tr|A0A0K2JDR5|A0A0K2JDR5_9FUSO Uncharacterized protein OS=Leptotrichia sp. oral taxon 212 GN=AMK43_08625 PE=4 SV=1
------------------------------ELLKNEIQKADAVVIGAGAGLSTSAGFT-FEKYFDFIKEYGIRDIYSGGFYPPNDEIRWAWWARHIYFNR
-YVKAPKPVYNELFSFLK--DKDYFVITTNVDHQFQKAGFDRLFYTQGDYGLFQSVNQIQTYDNEEPAELIPKCPDDG--SDMTTNLRADSSFVEAAEKY
SEFLNMHVLFLELGVGANT-PVIKYPFWYMNTKAVYVCINYQEAFCPNERSICLEGDIGEVLKGIQ-------------
>tr|V2XJA0|V2XJA0_9FIRM Uncharacterized protein OS=Catonella morbi ATCC 51271 GN=GCWU0000282_002363 PE=4 SV=1
------------------------------SRLKSELESADAVVIGAGAGLSTSAGFT-FEKYFDFARKYGISDMYSGGFYPPDAETKWGWWARHIYFNR
-YVESPVPVYKNLLSLVK--DKDYFVLTTNVDHQFQKAGFDRLFYTQGDYGLFQSVNAIQTYDNEEPTELIPKCPDDG--SDMTTNLRADSSFVEACKSY
NDFLGRHILYLELGVGANT-PVIKYPFWQKNNKAVYACINYGEAFCPKDRSICIYGDIGAIFKKCV-------------
>tr|I5AX88|I5AX88_EUBCE Uncharacterized protein OS=[Eubacterium] cellulosolvens 6 GN=EubceDRAFT1_2709 PE=4 SV=1
------------------------------SRLKTEIKEADAIVIGAGAGLSTSAGLT-LEKYYDFAKRFGIRDMYSGGFYPPSEEIRWAWWARHIYFNR
-YIDAPKPVYRDLLKMVS--DKDYFVITTNVDHQFQRAGFDRLFYTQGDYGLFQSVNAIQTFDNEEPSEMIPKCPDDG--SDMTMNLRADDSFVEASAAY
SDFLGQHILFLEIGVGANT-PVIKYPFWQNNPKAVYACLNYNEALCPRERSLCIDGDSGEVIEQLM-------------
>tr|C9KLM1|C9KLM1_9FIRM Uncharacterized protein OS=Mitsuokella multacida DSM 20544 GN=MITSMUL_04105 PE=4 SV=1
------------------------------AVLREKLAQADALLVGAGAGLSTAAGLS-FQKYADFAEKYGIRDMYTGGFYPSSPEIYWAWWSRHIYFNR
-YVDAPSDVYPTLRHLVE--DKDYFVLTTNVDHQFQRSGFDRLFYTQGDYGLLQSVQEVATYDNREPKELVPVCPDDG--RAMMVSVRCDGRFVEAQARY
KAFLDDAILYLELGVGLNT-PVIKYPFWYKNPNAFYTSINLSGAACSSKRSLCIEADIGKVLHDLS-------------
>tr|A0A0B2JYU7|A0A0B2JYU7_9FIRM Uncharacterized protein OS=Anaerovibrio lipolyticus GN=NZ47_07780 PE=4 SV=1
------------------------------ERLKTEIKNTQAIVIGAGAGLSTAAGLT-FEKYCDFAEQYGINNIYAGGFFPPSEEIKWAWWARHIYFNR
-YVDPPKSVYKDLLSLVE--NQDYFVLTTNVDHQFQRAGFDRLFYTQGDYGLFQSTNSDETYDNEEPSELIPKCPDDG--SPVVMNLRSDDTFVEAAIAY
NQYINKHVLYWELGVGANT-PGIKFPFWEANKNAVYACVNYGEAFCPEERSICIDGDIAELLQRL--------------
>tr|J5GN83|J5GN83_9FIRM Uncharacterized protein OS=Peptostreptococcaceae bacterium AS15 GN=HMPREF1142_1682 PE=4 SV=1
------------------------------EKLKNEIKNTKAIVIGAGAGLSTSAGLS-FEKYFDFAEKYGIRDMYSGGFYPPNGETRWAWWARNIYFNR
-YVAPTKPVYKKLLSILK--DRNYFVITTNVDHQFQRAGFDRLFYTQGDYGLFQSVNKIQTYDNEESTSLIPKCPDDH--SDVTMNLRADDSFVEASESY
YEFLDRHILFLELGVGANT-PVIKYPFWQKNKKATYACINYGEAFCPRDRSICIDGDIGEILDVI--------------
>tr|E0QGA7|E0QGA7_9FIRM Uncharacterized protein OS=[Eubacterium] yurii subsp. margaretiae ATCC 43715 GN=HMPREF0379_0055 PE=4 SV=1
------------------------------EKLKNQIKKSDAIVVGAGAGLSTSAGLS-FEKYFDFTEKYGIRDMYSGGFYPPDDEIKWAWWARNIYFNR
-YIEPPKAVYKKLLSILK--DKNYFVITTNVDHQFQRAGFERLFYTQGDYGLFQSINKNQTYDNGNPTNLIPKCPDDN--SDVTMNLRADDSFVEASESY
YEFLDKHILFLELGVGANT-PVIKYPFWQRNKNAIYACINYGEAFCPIDRSICIDGDIGEILDVI--------------
>tr|M2Q4E6|M2Q4E6_9FIRM Uncharacterized protein OS=Eggerthia catenaformis OT 569 = DSM 20559 GN=HMPREF9943_00679 PE=4 SV=1
------------------------------KMLKNEIQNAEAVVIGAGAGLSTSAGLT-FERYFDFAKKYGISDMYSGGFYPPDSETKWAWWARHIYFNR
-YVEPPIPVYRKLLSLLK--NKNYFVITTNVDHQFQRAGFDRLFYTQGDYGLFQSVNKIQTYDNEQPTSMIPKCPDDN--SDVTTNLRADDSFVEASEAY
YNFINKRILFLELGVGANT-PVIKYPFWHMNERAVYICINYGETFFPSDRSICIDGDIGKVLNEIG-------------
>tr|X8K2X2|X8K2X2_9FIRM Uncharacterized protein OS=Eubacterium sulci ATCC 35585 GN=HMPREF9092_0171 PE=4 SV=1
------------------------------DMLKDALENSDSVVIGAGAGLSTSAGFT-FDRYFDFARKYGIKDMYSGGFYPPDDETRWAWWARHIYFNR
-YVKASKPVYENLLALIE--DKDYFVITTNVDHQFQKAGFDRLFYTQGDYGLFQSLNRNQTYDNEKPSGLIPRCIDDN--SDVTMNLRADNSFVEASERY
YNFLHSKALYLELGVGANT-PVIKYPFWHSNKNAKYACINYGESFAPMDRSICIDGDIGEVIKKLL-------------
>tr|A0A0B4S0E8|A0A0B4S0E8_9FIRM Uncharacterized protein OS=Parvimonas micra GN=NW74_00800 PE=4 SV=1
------------------------------EFLKNEIENADAIVIGAGAGLSTSAGFT-FEKYFDFSKKFGITDMYSGGFYPPDRETLWAWWARHIYFNR
-YIEPPKSVYRDLFSIVK--DKEYFVITTNVDHQFQRAGFDRLFYTQGDYGLFQSVNQNQTYDNEEPTDMIPKCPDDD--LDVTMNLRADSSFVEASKEY
YNFLDKHILFLELGVGNNT-PVIKYPFWQINKNSVYACINYKEAFCPTDRSICIDGDIGDVLEKIM-------------
>tr|K0XT59|K0XT59_9FIRM Uncharacterized protein OS=Lachnoanaerobaculum sp. OBRC5-5 GN=HMPREF1135_00583 PE=4 SV=1
------------------------------QRLKNEIRSCDAILIGAGAGLSTSAGLS-FDKYFDFGKAFGIKDIYSGGFYPPKKEIFWAWWARHIYFNR
-YVDAPKPVYKDLLNLVK--DKDYFVITTNVDHQFQRAGFDRLFYTQGDYGLFQSINDCKTFDNKEPTDLIPKTPS-G--DDVTTNLRADDTFVEASSNY
ADFINLHILFLELGVGANT-PVIKYPFWQYNKKAVYACLNYGEAFCPEDRSICIDGDIGEILSQIK-------------
>tr|R5IBP9|R5IBP9_9FIRM Uncharacterized protein OS=Ruminococcus sp. CAG:60 GN=BN729_00606 PE=4 SV=1
------------------------------QQLKEAIEEADAVVIGAGAGLSTSAGFV-FSKYGDFAGKYGFEDMYSGGFYPDSLEEYWGYWSRYIYINR
-YMNAPKPVYENLLRLVQ--EKDYFVLTTNVDHCFQKAGFDRMFYTQGDYGLWQCSRCHHTYDNRKPSELVPHCPKCG--APMTMNLRADSTFVEAASRY
DDFIRMKVLFLELGVGYNT-PGIKYPFWQANPKAVYACINYRDAACQTNQAICIEGDIERL------------------
>tr|F0ELN0|F0ELN0_ENTCA Uncharacterized protein OS=Enterococcus casseliflavus ATCC 12755 GN=HMPREF9087_2322 PE=4 SV=1
------------------------------QKVYQKITEAEAIVIGAGSGLSAAAGLT-FKKYRDYIDHYHLTDMYSAGFYPDSLETYWGYWSKHVFHNR
-YQPEALPLYKELLSLVE--EKNYFVITTNVDHQFQKTGFDRLFYTQGDYGLFQCSRCHNTYENESPKHLIPYCPKCG--QPMRVNLRIDQFFVQAANRY
KEFLGTKIVFWEIGIGNNT-PSIKYPFQERTNQSTYIVCNQQAQRIPD-KTIILQGNIVEAIREID-------------
>tr|D4CEY4|D4CEY4_9CLOT Uncharacterized protein OS=Clostridium sp. M62/1 GN=CLOM621_08003 PE=4 SV=1
------------------------------SRLKHQLDTADAVIIGAGAGLSASAGFT-FEKYGDFIQKYGFRDMYSGGFYPETLEEHWAYWSRYIYINR
-YLDAPKPVYGDLLRLVR--DKDYFVLTTNVDHCFQKAGFDRLFYIQGDYGLWQCSRCSQTYDNEAPGELVPHCPVCG--APMSMNLRADMTFVEAAQRY
EDFLRMHILYLELGVGGNT-PSIKYPFWRCNPKAAYACVNLSEAYCPKRQAICIEGDIGRTLNALH-------------
>tr|R6CNW3|R6CNW3_9CLOT Uncharacterized protein OS=Clostridium sp. CAG:242 GN=BN558_01464 PE=4 SV=1
------------------------------SRLKQEVLTADAIVIGAGAGLSTSAGLT-FEHYGDFIQKYGFHDMYSGGFYPETLEEHWAYWSRYIYINR
-YLDAPKPVYNDLLKLVQ--DKDYFVLTTNVDHCFQKAGFQQLFYTQGDYGLWQCSKCHQTYDNEFPSELVPHCPICG--APMSMNLRADMTFVEAAAQY
ENFLGQHILYLELGVGNNT-PGIKYPFRKYNPKAVYACINLLDSYCPKEQTICISRDIGMVLNELS-------------
>tr|R5BU10|R5BU10_9FIRM Uncharacterized protein OS=Blautia hydrogenotrophica CAG:147 GN=BN499_00023 PE=4 SV=1
------------------------------KKLKFEIEHADAILIGAGAGLSASAGLV-FYENSDFAGKYGLRDMYSAGFYPETLEEYWAYWSRHIYVNR
-YQPQIDEPYTSLLKLVQ--DKDYFIITTNVDHSFQKAGFDRLFYTQGDYGLWQCPRCCNTYDNYNPTSLIPYCTHCG--SPMTMNLRIDNTFVEASLRY
HDFIHLHILYLELGVGYNT-PIIKYPFWQANIKAVYACVNYKENFVPPKQSICINVDIKQVFN----------------
>tr|A0A0D8J5L4|A0A0D8J5L4_9FIRM Sir2 silent information regulator family NAD-dependent deacetylase OS=Ruminococcaceae bacterium 585-1 GN=TQ39_02525 PE=4 SV=1
------------------------------ERLKQALETADAVLIGAGAGLSASAGFT-FHRYSDFEAKYGFHDMYSGGFYAPTPEEHWAYWSRYIQVNR
-YEDAPRPVYDSLYRLIS--EKDYFVLTTNVDHCFQKAGFDRLFYTQGDYGLLQCCECHRTYDNRAPTALIPRCPKCG--KPMAVNLRSDDRFAEAAGRY
ADFLGMHILLWEIGVGYNT-PGIKYPFWQANPNAVYACLNSGQAVCPGRQSICIDGDAGMLLQALL-------------
>tr|R5HDU0|R5HDU0_9FIRM Uncharacterized protein OS=Firmicutes bacterium CAG:114 GN=BN469_01199 PE=4 SV=1
------------------------------ARLRETIQTAEAIIIGAGAGLSTSAGFS-FKENPDFIAKYGFSDMYSAGFYPETLEEHWAYWSRYIFINR
-YQNPPKPVYQNLFHLVQ--SKDYFVLTTNVDHCFQKAGFDRLFYTQGDYGLWQCSKCHNTYDNETPSELVPYCPLCG--APMSMNLRADSTFVEAANRY
QNFLGQHILYLELGVGENT-PGIKYPFWNHNANATYACVNLSEADIPAPQSIGVYGDIGDVLREIV-------------
>tr|B1C2M0|B1C2M0_9FIRM Uncharacterized protein OS=[Clostridium] spiroforme DSM 1552 GN=CLOSPI_01482 PE=4 SV=1
------------------------------YKLKNAFLQADAIIIGAGAGLSTAAGFT-FMKYSDFHEKYGIANMYAGGFYPDSLEEYWAYWSRYIYINR
-YQEPLKPVYQKLYQLVK--DKDYFVLTTNVDHCFQKAGFDRLFYSQGDYGLFQCSKCQPTYDNEKPTQAIPYCPHCG--ALMTMNLRIDDTFVEAAKCY
HEFLKQHILFLELGVGNNT-PGIKYPFWNLNKNALYACINVQDTYYPKKQTICIQEDIYKVIK----------------
>tr|S0ILY2|S0ILY2_9FIRM Uncharacterized protein OS=Eubacterium sp. 14-2 GN=C805_03778 PE=4 SV=1
------------------------------KNLRQKIQHAEAILIGAGAGLSASAGFT-FEDHSDFMETYGFQDMYSAGFYPETPEEYWAYWSRYVYINR
-YRNPPETVYHDLYSLIQ--HKDYFVLTTNVDHCFQKSGFDRLFYTQGDYGLWQCSRCHNTYDNEIPSELIPHCPFCG--APMSMNLRSDSTFVEAAGRY
QDFLNRNILYLELGVGNNT-PGIKYPFWQYNPNAFYICINLAETCVPAKQSICIALDAGTILKQLA-------------
>tr|D1Y218|D1Y218_9BACT Uncharacterized protein OS=Pyramidobacter piscolens W5455 GN=HMPREF7215_2045 PE=4 SV=1
------------------------------QKLRAALRDCPTVVIGAGAGLSAAAGFD-FRKYGDFAARYGFSDMYSGGFYRETFEEQWAFWSRSIYVNR
-YMDAPKRTYRRLRELVR--GKDYFVVTTNVDHCFQKARFDRLFYTQGDYGLWQCSTCHRTYDNREPSKLIPLCPKCG--KPMTMNLRSDDAFVEAARRC
EEFLTGKALYLELGVGSNT-PGIKYPFQIFNPDAVYALVNAQPQSVPEARSIAVVGDIDATLEALR-------------
>tr|R5IM76|R5IM76_9CLOT Uncharacterized protein OS=Clostridium sp. CAG:7 GN=BN757_02617 PE=4 SV=1
------------------------------LQIKEKIEEAEAVVIGAGAGFSTSAGFV-FEKYSDFRKKYGFSDMYSGGFYPKTLEKHWGYWCRYIYINR
-YMDAPKPVYQNLYDLVK--EKDYFVLTTNVDHCFQKAGFARIFYTQGDYGLFQCSECHKTYDNEEPTGLIPYCPRCG--KPMSMNLRSDQTFVEAAERY
EKFIKQKIVFLELGVGYNT-PGIKYPFWQNFQHAFYVCLNQGEAYAPEKKSVCMNEDIGEILKEL--------------
>tr|R6YC46|R6YC46_9FIRM Uncharacterized protein OS=Firmicutes bacterium CAG:94 GN=BN815_00993 PE=4 SV=1
------------------------------ERLAAALQEADAVLVGAGAGLSTSAGFA-FRRYGDFEAAYGFHDMYSGGFYPPTLEEHWAYWSRFIFLNR
-YCDPPKPVYQNLLELVK--EKDTFVLTTNVDHCFQKAGFDRLFYTQGDYGLWQCSKCHDTYDNQEPTELVPRCPVCG--APMSMNLRADNTFVQAAQRY
EWFLELRVVFLELGVGYNT-PGIKYPFWQANPRATYVCINYQDALCPRQQSLCIQRDIHQVLEQLV-------------
>tr|R6PIR5|R6PIR5_9CLOT Uncharacterized protein OS=Clostridium nexile CAG:348 GN=BN618_01106 PE=4 SV=1
------------------------------EKLEKQIQQADAIIIGAGAGLSTSAGFH-FKEYGDFANKYHFIDMYSGGFYPETLEEHWAYWSRYIYINR
-YMDAPNPVYNKLYSRVK--EKDYFVLTTNVDHCLQKAGFDRLFYTQGDYGLFQCSECHQTYNNEAPSELVPHCQKCG--KPMSMNLHADGTFVQASNRY
YEFLNLFILFLELGVGENT-PAIKYPFWRANPKAVYACINWGQAYAPKERSICIDQDIGEVLGKII-------------
>tr|A0A0D0SBG6|A0A0D0SBG6_9FIRM TWA4_scaffold00001, whole genome shotgun sequence OS=Lachnospiraceae bacterium TWA4 GN=P261_00544 PE=4 SV=1
------------------------------EQLKNEIKTADAIVIGAGAGLSTAAGHS-FEKYSDFKENYGIQDMYSGGFYPSSLEEYWGWWARHIYVNR
-YLNDSNGTYENLLDLVK--GKDYFVLTTNVDHQFQKAGFDRIFYTQGDYGLWQCSKCHNNYDNEQDSELIPRCPKCK--SPMTMNLRCDDTFVQANHCY
SDFINLHVLFLELGIGMNT-PVIKYPFWKYNKNAVYACLNYGEAYAPRSRSICIDADIKKVFE----------------
>tr|C0ETF3|C0ETF3_9FIRM Uncharacterized protein OS=[Eubacterium] hallii DSM 3353 GN=EUBHAL_00684 PE=4 SV=1
------------------------------EQLKEKIEEADTIIIGSGAGLSTSAGFT-FTKYSDFQKKYGFQDMYSGGFYPESFEEHWAYWSRYIYINR
-YMDAPKPVYEKLYDLVK--EKDYFVLTTNVDHCFQKAGFDRLFYTQGDYGLFQCSVCHQTYDNEEPSELVPVCPKCG--KPMSMNLRADNTFVEAAERY
SEFLHTKTVFLELGTGYNT-PGIKYNFWNDWDDATYACINLNEAAAPTEKSICVGADIGEVLNQIF-------------
>tr|A0A095XCK2|A0A095XCK2_9FIRM Uncharacterized protein OS=Tissierellia bacterium S5-A11 GN=HMPREF1633_15425 PE=4 SV=1
------------------------------LEVKEWLKEADAVILGIGPGLSKAGGVSLLMEEMPDLKARGLETVLKGMRVYWNPSEYWAFWSNLIKNLR
-YETKPMEVYKEVFDLVK--DKPYFVISTTVDGQIEKAGFDRVYMPQGDMAYSQCYECNNRYYNEKREDILGRCPSCG--KYLVPNIRMEENFVAQRKEF
VDFVDKKLLFLEFGEGFDQ-AGIRYPFETELDKAKLVRFNTSDPEVPEDKALGIKEPIEKCLKDLM-------------
>tr|M1LSB1|M1LSB1_9CLOT NAD-dependent protein deacetylase, SIR2 family OS=Clostridium saccharoperbutylacetonicum N1-4(HMT) GN=Cspa_c20740 PE=4 SV=1
------------------------------REAVELIKNADYVVIGAGSGFTASGGIYYLFKKFPKHYQMGFKNILEMQSAFDNVLSYWGYWARHIQNIR
-YNTPATKPYLTLMELLK--NKEYFICSTNVESQFEKAGFPKMFAPQGNYGLFQCSKCTQVYDNKEKEEDIPRCPKCG--EFLVPNLRVDDTFVQNISKY
EKFIDKKLVLLELGVGYNT-PGIRYPFENNYPFANLIRINMSAAGVPTKKSVSISEDIGKALSDIL-------------
>tr|R9SNK7|R9SNK7_9EURY SIR2 family protein OS=Methanobrevibacter sp. AbM4 GN=Abm4_1356 PE=4 SV=1
------------------------------KKAYDAISDAENIVIGVGSGLSAAGGLNYFFKEYPQYARLGYKTIGDIMGKFMNACKYWGFWSHHINEIR
-YKTPATEPYLNLYKLVK--DKNYYIISTNVDYQLEKAGFSKIFEPQGQYSQFQCIICSNVYYNEKSSDDIPYCPNCG--EFLIQNLRCDNRFVENYNNY
VEFIDKNTVLLELGVGYNT-PTIRFPFEQYYLNMTLIRMNLGDARIPSK-RISIDNDLNKSLKDIV-------------
>tr|A0A0A7FZ26|A0A0A7FZ26_9CLOT SIR2 family protein OS=Clostridium baratii str. Sullivan GN=U729_2119 PE=4 SV=1
------------------------------NDVVKKIEDADAIVIGIGAGMTASGGINYTVKEFPEYYNLGFKSIMEIQSAFKNKLSYWGYWSRHIDKIR
-YKTELLAPYKNLVKIIS--NKNYFICTTNADGQTQKSGFDKIFAPQGNYDVFQCIVCSRVYSNESDEKFIPKCPKCG--DYLIPNLRCDDKFVENLDQY
RNFIEKNIIFIELGVGFNS-PGIRFPFEQYSQNATLIRINKGMAMVPKSKSICIDDDINEVLTQIL-------------
>tr|A0A0C7JY86|A0A0C7JY86_CLOSO NAD-dependent protein deacetylase OS=Clostridium sordellii GN=UMC4404_06521 PE=4 SV=1
------------------------------NDIVKKIENADAIVIGIGAGMTASGGISYIVKEFPEYANLGFKSIVEIQSAFRNKLSYWGYWARHIDRIR
-YKTKLLAPYKNLVEIIS--NKNYFICTTNADGQTQKSGFNKIFAPQGNYDVFQCIVCSRVYFNENDEKFIPKCPKCG--NYLIPNLRCDDKFVENLDKY
RDFINKNIVFLELGVGFNT-PGIRFPFEQDSPNATLIRINKGMATVPKSKSICIDDDINEVLIQIL-------------
>tr|F4MQ48|F4MQ48_MYCML Uncharacterized protein OS=Mycoplasma mycoides subsp. capri LC str. 95010 GN=MLC_5030 PE=4 SV=1
------------------------------KKLND--------LINQNDSLIIAIGSEIFENNSDFIKEFCFIDFKQASVYPLDIKNYWAFFSRYIKLNY
-FDQKLDNSFIDLKNYLD--NKNYFIITTNRDNSLELAGFDKIFYLDSKLNLLECSKCSDLYINDDELEQIPVCKKCN--SYLKVHQRFCQVFIKTQNNY
QKFIDKKMLFWEIGINFNN-QLVKKPFWQEFKKATYLAMNKKIYRIPLSKTITYTNDLNLAIKNLE-------------
>tr|L5L823|L5L823_9MOLU Uncharacterized protein OS=Mycoplasma feriruminatoris GN=D500_0801 PE=4 SV=1
------------------------------KQLDD--------LINQNDSLLIAIGSEIFENNSDFIKEFNFIDFKQASVYPLDISNYWAFFSRYIKLNY
-FDKKLDKTFIDLKNYLE--NKNYFIITTNSDNSLEQAGFDKIFYLDAKYNLLECSNCTDLYTNDLSLDLIPRCSKCN--SFLKVHQRYCRTFIQSENKY
QNFIDKKMLFWEIGVNFNN-QLVKQPFWKSFSNATYLAMNQKVYRIPLSKSITYTNDLHLAIKNLL-------------
>tr|A0A0C2W7F2|A0A0C2W7F2_MYCCA SIR2 family protein OS=Mycoplasma capricolum subsp. capricolum GN=MCGM508_03965 PE=4 SV=1
------------------------------VKLDK--------LICDANSIVVALGPEIFEENFDFIKEFKFIDFKQASVYPLDISNYWAFFSRFIKLNY
-FDKKQNQILSNLKNYLE--NKNYFILTTNSDQSLEDLNFDKVFELEAKYNLLECSKCSNLYTNDQDLELIPRCSKCN--SYLKVHRRFCQVVIESKNKY
QEFLNQKILFWEIGVNYNY-HLIKKEFWKEFKNATYLAMNQKVYRIPLSKTITYTNDIYQAINNLL-------------
>tr|K7X9A2|K7X9A2_MYCHR NAD-dependent protein deacetylase of SIR2 family OS=Mycoplasma hyorhinis SK76 GN=MOS_316 PE=4 SV=1
------------------------------EKLLSLINEAEHILVGIGSGLTSADGIG-FEDNADFISRYKFLDMLQASLFHDNWQTYWAFHSRFIKLNY
-LEQPAGKSFINLAKILE--NKDFFIITTNSDNSIEAAGFDKVFYIQGKYNLLQCSQCHNRYQNDQDMSLLPHCPQCD--AFLEVNKRIYKGMVEEQKNY
LSFINKKTMFLEIGVGYTT-PQIKHPFWNKNPSSLYVVLNNKNYRIDKNKTIIFNDDLDKIIDEVK-------------
>tr|A0A0C5WW44|A0A0C5WW44_9MOLU Deacetylase SIR2 OS=Mycoplasma dispar GN=MDIS_03765 PE=4 SV=1
------------------------------KKIKEIIKKADAILVGVGSGITDADGNN-FSHNQDFIEKYKFIDMLQASLFDDSWQIYWAFHSRFAKINY
-LDLKASPSFLNLKKVLE--NKNYFIITTNSDSFFEKSDFPKIFYIQGKYNLMQCSKCKNLYKNDNDFKLLPRCPECD--AFLEINKRIFKGMVEQKKKY
NDFIEKNIIFLEIGVGFTT-PQIKFPFQEKFKNATYLVLNQKRYRKNKEKSHFFYEDIKILLEKIA-------------
>tr|S5G9J8|S5G9J8_MYCHY Uncharacterized protein OS=Mycoplasma hyopneumoniae 7422 GN=MHL_3081 PE=4 SV=1
------------------------------IKIKKILDSADAIVVGVGSGLTSADGNN-FSDNKDFIEKYRFLDMLQASLYDGSWETYWAFHSRFAKVNF
-LDLIESESFFNLKKILE--NKNFFIITTNSDSFFEKSGFDKIFYIQGKYNLMQCSKCKNLYQDDGDYNLLPKCPECN--AFLEINKRIFKGMVEQKANY
NNFIDKKLVFLEIGVGFTT-PQIKFPFQEKFKHAKYLVINQKKYRTNKEKSYFFHEDIKLLLQKIT-------------
>tr|N9V1G9|N9V1G9_9MOLU Uncharacterized protein OS=Mycoplasma bovigenitalium 51080 GN=MBVG_4600 PE=4 SV=1
------------------------------KKLNNLISQADAIVLGIGSGMTAADGIG-FQENSDFIKAFGFLDMLQASVYHDDIQNYWAFHSRFMKLNY
-FDQQPSQSFINLKQYLA--DKNYFIITTNSDNALEAAEFDKIFYIQGKYNLLQCEKCHNRYSNDAPLDLIPRCPKCN--SFLEVNKRLEKGMVEEKARY
EAFIDKKILFWEIGVGYST-PMIKHPFWLEIPHAQYLAMNNRVYRLPQSKTIVETNDIKDSIASLL-------------
>tr|A0A059XQS2|A0A059XQS2_9MOLU SIR2 family protein OS=Mycoplasma californicum GN=MCFN_01160 PE=4 SV=1
------------------------------SKLNELIMQADAIVVGIGSGMTAADGIG-FRENSDFIDEFGFLDMLQASVYHEDIRNYWAFHSRFMKLNY
-FDQPASQSFMNLKQYLS--DKNYFIITTNSDNALEAVDFDKIFYIQGKYNLLQCEKCHNRYSNDEPYELIPLCPECG--AFLEVNKRLGKGMVEEKARY
EQFINKKILFWEIGVGYST-PMIKHPFWEKFDKATYLAMNNKSYRLPQAKTVVETNDIKETIQALL-------------
>tr|E4PYV9|E4PYV9_MYCBG Uncharacterized protein OS=Mycoplasma bovis (strain ATCC 25523 / PG45) GN=MBOVPG45_0011 PE=4 SV=1
------------------------------KELDALINEADAIVIGIGSGMTSADGIG-FVENKDFIDEFKFLDMLQASVYHDDIQNYWAFHSRFMKLNY
-FDQPASESFLKLKEYLK--GKSYHIITTNSDNSLEAADFDKIFYIQGKYNLLQCSRCHNLYSNDKPLEIIPRCPKCN--DFLEVNKRLGKGMVEEKKMY
EDFIGQKILFWEIGVGYST-PTIKFPFWEKYLSSKYIAMNNKSYRTPLQRTYVWTDDIKDTINKLL-------------
>tr|M9WAK8|M9WAK8_9MOLU Uncharacterized protein OS=Mycoplasma putrefaciens Mput9231 GN=MPUT9231_6300 PE=4 SV=1
------------------------------KQINALLANADAIVIGIGSGMTSADQIG-FQKNKDFIDKFMFLDMLQASVYDKDIQNYWAFHSRFMKLNY
-FDQPATESFINLKNYLD--DKNYFIITTNSDNSLEASGFDKIFYIQGKYNLLQCSKCHNLYSNDKDLDLIPRCVKCN--EFLEVNKRLHKGMVEEKQAY
EQFIDKKLVFLEIGVGYAT-PTIKQPFWKKYQNSIYLTLNNKLYRVPKNRTYNCFEDIKKTINELL-------------
>tr|A0A0L1IJ48|A0A0L1IJ48_9MOLU Uncharacterized protein OS=Mycoplasma sp. HU2014 GN=AB668_01690 PE=4 SV=1
------------------------------KQLNDLLVNADAIVIGIGSGMTSADQIG-FQENKDFIDEFKFLDMLQASVYDKDIQNYWAFHSRFMKLNY
-FDQQATESFINLKNYLN--DKNYFIITTNSDNSLEVSGFDKIFYIQGKYNLLQCSKCHNLYSNDKDLNLIPRCVKCN--AFLEVNKRLCKGMVEEKQAY
EQFIDKNIVFLEIGVGYAT-PMIKHPFWEKYQNSTYLTLNNKLYRIPQNRTYNCFEDIKITIAKLL-------------
>tr|W5UT57|W5UT57_9MOLU Uncharacterized protein OS=Mycoplasma bovoculi M165/69 GN=MYB_01485 PE=4 SV=1
------------------------------KEILDLLSDADTIVVGIGAGLTAAANIG-FEQHGDFIEKYRLLDMLQASLFDPNWQTYWAFHSRFIKLNC
-FDLPKSSIFSKLKDILE--TKNYFIITTNSDNSLLVNGFNKIFYIQGKYDLLQCSQCSNLYQKNESLELLPKCPNCD--AFLEVNKRIFKGMVEQKQKY
ESFLDKKVVFFEIGVGYTT-PQIKWPFWQINPKAKYLVLNSKNYHLQEKQSKIFNEDIAKLIEQIW-------------
>tr|C5J6L4|C5J6L4_MYCCR Uncharacterized protein OS=Mycoplasma conjunctivae (strain ATCC 25834 / HRC/581 / NCTC 10147) GN=MCJ_004200 PE=4 SV=1
------------------------------QEILALINQAEAIVVGIGSGLTAADGIG-FEEHGDFIEKYRFLDMLQASLFDPNWQTYWAFHSRFIKLNY
-FDLPKSASFLKLKEILA--NKNYFIITTNSDSSLEVNDFDKIFYIQGKYNLLQCSKCQNLYKNDKNATLLPKCPNCD--AFLEVNKRIYKGMVEQQKAY
DDFLDKKVLFWEIGVGYTT-PQIKWAFWKLNRKSTYLVFNAKNYHISSKQTKIYHYDIAKLIDKVW-------------
>tr|A8H4N4|A8H4N4_SHEPA Uncharacterized protein OS=Shewanella pealeana (strain ATCC 700345 / ANG-SQ1) GN=Spea_2201 PE=4 SV=1
------------------------------TSIPALLNQADAILIGAGAGLSAAAGINYKFAQFPGWVKKGFTAQYQLMGYPWTQLEQWGYYKAHLEYVY
-FGQDDNQLYRQLRRAVA--DKDYFVMTSNVDGLFYKNGFDRFYSPQGDYGKIQCTTCSDVWDIRPDEIAIPRCPNCG--GEMFIHARIDGSFIDERIKL
IDWLDKQLLLLDLGSGFNT-PTIRMPMEQMLPNANLIRVNLDHAEVPATKAIGIEADLNEFIEVLT-------------
>tr|B1KG03|B1KG03_SHEWM Uncharacterized protein OS=Shewanella woodyi (strain ATCC 51908 / MS32) GN=Swoo_2432 PE=4 SV=1
------------------------------EHAREALADAEVVFIGAGAGLSASAGLDYAFAEFPGMLQYGFRFQYQLMGYPDDEALKWGYLATGLNHVY
-HSQQ-TQVYQDLLSLVD--ERDSFVITSNVDRYFHKNGFDNIYTPQGDYERFQCMTCTDVWDGRENRSTLPVCPNCG--GPVFMNVRGGSWFIEQADAI
SNWLNRKMAIVEIGAGFNT-PGIRLPLENKLPDARLIRISKEHADGPVSLQMTADEALSKMISG---------------
>tr|A0A090TXE1|A0A090TXE1_9VIBR NAD-dependent protein deacetylase of SIR2 family OS=Vibrio maritimus GN=JCM19240_379 PE=4 SV=1
------------------------------KRIAEKLAQADAVLIGAGAGLSAAAGINYRFAEFPGWVKKGFTAQYQLMGYPWTQLEQWGYYKAHLEYVY
-FGQQHNPLYQRLFDLVK--DKDYFVMTSNVDGLFYKNGFDRLYTPQGDYGKIQCTVCSQVWDIAPDERGIPKCPNCG--SHMFIHARIDGSFIDEYRNL
MTWLNNQVLLLDLGSGFNT-PTIRLPMENQMPNAHLVRVNLEHDEVSLHKASLFKQDIKGFISELT-------------
>tr|A0A011PQV0|A0A011PQV0_9PROT Uncharacterized protein OS=Candidatus Accumulibacter sp. BA-93 GN=AW11_01291 PE=4 SV=1
------------------------------KDTCVLIKESDGILIGAGAGLTAAAGLNYAFARFPAWKRRGFLRQYDLVGYRWTPLEMWGYWATQLNYVY
-YSQSTNPLYQKLRSLIG--DRNCFVMTSNVDELFHKNGFDRIYSPQGSYGKIQCTICCQAWDMKPDEAAVPVCPNCG--GTMFPNVRVDGSMVDQRERL
LRWLGKKLLLLDLGSGYNT-PAIRLPMERDFANSALIRVNMEHADVPRHKSICIKGDISEFIEQTS-------------
>tr|A0A0C5V8H7|A0A0C5V8H7_9GAMM NAD-dependent protein deacetylase, SIR2 family OS=Gynuella sunshinyii YC6258 GN=YC6258_03649 PE=4 SV=1
------------------------------VKVKALLNECDAVLIGAGAGLTSAAGIDYAFARFPGWIKRGFTAQYQLMGYSWSQEEQWGYYKTHLDYVY
-FSQQSNPLYQSLYQLVK--DKDYFVMTSNVDGHFYKNGFDRIYAPQGDYGLIQCTQCTKVWEIKPSALGIPKCPVCG--SDMFIHVRIDASFIDERQAL
FDWLRKRVLLIDLGSGFNT-PTIRLPMEKILADATLVRVNLDHANTTLNKVISVQSDIAEFIKNIS-------------
>tr|A8FSV1|A8FSV1_SHESH Phosphatase OS=Shewanella sediminis (strain HAW-EB3) GN=Ssed_1313 PE=4 SV=1
------------------------------STAKAWLEESEFILFSAGAGMTAAAGINYLFKRYPAMLQYGFNAQYELIGFDWTPDLQWGYWAAHVNFVR
-FKWPQTEVYQQFHQLID--NENTFVMTSNVDAMFERNGFDRIYTPQGDYALLQCTTCTDVWPWKADNSLIPCCPNCG--GTVFPNVRSDASFIDNGRGL
EKWLDKKGVIIEVGAGFNT-PSIRWPNEHCMPDWKLLRINFTHADVPDKRAIGFKGNAANIIQNLQ-------------
>tr|A0A0F5ZQF2|A0A0F5ZQF2_9GAMM Uncharacterized protein OS=Grimontia sp. AD028 GN=RN22_24125 PE=4 SV=1
------------------------------RNVSTLIKDADAILIGAGAGLTAAAGINYKFAKYPGWKKKGFNAQYELMGYPWSQQEQWGYYKVHLEYVY
-FSQGANPLYEALYDLVR--DKDYFVMTSNVDGLFYKSGFSRFYAPQGDYGKIQCTKCSQVWDIKPSEQGVPKCPNCG--EDMFIHARVDGSFIDERQAL
IQWLEKKVVVLDLGSGFNT-PTIRIPMEQHFPNASLVRVNMDNASTPPFKATSIKGDIAEFVHQTR-------------
>tr|A0A0M8WG70|A0A0M8WG70_9NOCA NAD-dependent protein deacetylase of SIR2 family OS=Nocardia sp. NRRL S-836 GN=ADL03_14725 PE=4 SV=1
------------------------------MTVERLLDEADRVLVAAGAGLSAAAGYDYRFAEFPVLHRMGLRARYQLIGLP-PPRLLWGYWSVHVDDIR
-FGPAPNPMYARLREVIG--ARDNFVLTSNVDGLFARNGFTDVWSPQGDYGRYQCETCTRTWDSRPEASAVPTCPRCA--GPVFLNVHKGPEYVADGQRL
REWV-GDLLVVEIGAGYST-PTIRRPVESRLPRARLVRINRDHAEVPAERSVSVRADVAEVLGLP--------------
>tr|A0A0F0GRR1|A0A0F0GRR1_NOCAE NAD-dependent protein deacetylase of SIR2 family OS=Lechevalieria aerocolonigenes GN=UK23_30765 PE=4 SV=1
------------------------------MTFERWLDESDRVLIAAGAGLSAAAGYDYRFAEFPALHRKGLWARYQLIGLP-PPRLLWGYWSVHVNDIR
-FDPAPNPLYRRLRSTIG--ERDHFVLTSNVDGLFARNGFGDVWSPQGDYGRYQCETCTRTWESRPEAGAVPSCPRCG--GAVFLNVHKGPEYVPAGRRL
RSWL-GRLLVVEIGAGFST-PSIRWPVESRVPGARLVRINRDHAEVPGAL--AVRADVTEVLA----------------
>tr|A8RH19|A8RH19_CLOBW Uncharacterized protein OS=Clostridium bolteae (strain ATCC BAA-613 / WAL 16351) GN=CLOBOL_00289 PE=4 SV=1
------------------------------LALKRRLEQADAVVIGAGSGLSAAAGLT-FEDHREFIERYGMRDMYSAGFYPPTQEEKWAYWSRHIYYNR
-YDMPAAKLYRDLYAMMK--DKNHFVLTTNVDHQFWLAGFQCIFATQGDYGLFQCKQCHKLYDNEAPSCQVPKCPVCG--GDMEVHLRCDGNFVEAAVRY
ETFLEKTLVFLELGVGMNT-PGIKYPFWRKWKQAFYISVNLEQAWVPDDRSLVLKADIAHVLEHLA-------------
>tr|A0A0K9NG50|A0A0K9NG50_9FIRM SIR2 family protein OS=Dorea sp. D27 GN=HMPREF0980_00428 PE=4 SV=1
------------------------------KRLHDLIMEADAVAIGGGSGLSAAAGYE-FQKNAEFIDRYGMTDMYSAGFYPPTMEEKWAYWSRHIYCNR
-YDQKQSRLYMDIRSLVD--EKEYFVITTNVDHQFWAAGFDRIFAVQGDYGQFQCAKCHSLYDNERPAALIPKCPVCG--GNMEVHLRCDGYFIEACGRY
EQFIGKKLVFLELGVGMNT-PGIKYPFWQAYEHAFYICVNKGQAWAPADKALCVDTDIAEAVEQLM-------------
>tr|F7K3D0|F7K3D0_9FIRM Uncharacterized protein OS=Lachnospiraceae bacterium 3_1_57FAA_CT1 GN=HMPREF0994_00363 PE=4 SV=1
------------------------------KELHRCLEQAEAVVIGAGSGLSAAAGFT-FEEHREFIEKYGMTDMYSAGFYPASQEEKWAYWSRHIYYNR
-YDQPAGTAYTQMLSLVK--ERNYFVITTNVDHQFSLAGFERIFAVQGDYGLFQCKKCHKLYDNERPSELVPKCPVCG--GDMEVNLRCDIFFVETAEGY
ERFIGKKVLFLELGVGMNT-PGIKYPFWQWNPRASYVCINLGEALAPEERSLCINGDICKVISEVL-------------
>tr|C8P8A7|C8P8A7_9LACO Uncharacterized protein OS=Lactobacillus antri DSM 16041 GN=FC31_GL000865 PE=4 SV=1
------------------------------KIFADKIKKADHIVIGGASGLSAAGGGDFYKKHAKFYEKYGFKGAFAGMQHRDSQEEFWGYLATFLYTTQ
-HAEIRQP-YKDLQAILK--DRDYFIVTTNQDTQAIKA-FPKVAQIQGDHRFFQCSQCTDVWDAVKPTELIPRCPHCG--AEAFPWVRGYGNFLEEYQKI
SDDLHDKILFVELGVGRMT-PMIQEPFWANLPGAFDVMVNKDYQFLPEDKGVAIKGDIAKVLDDVK-------------
>tr|C7N0U2|C7N0U2_SLAHD Uncharacterized protein OS=Slackia heliotrinireducens (strain ATCC 29202 / DSM 20476 / NCTC 11029 / RHS 1) GN=Shel_00960 PE=4 S
------------------------------RRIRQALDTADLVLIGASNGLDMAEGLNIFAEAGDLAQACGARSVLEGMYRSGNLAQAWAWQARFACREW
-LDYNPGAVMEPLRKLVG--QTDHFVLTCNTDARFMRAGFDFVMQTEGTVARMVCSACCDRHASAEDLRLIPACPHCG--APLTLAVDEMRLQHPQMDVL
RDLLGGNIVVLELGVGLRN-GVIKQLLARAEPNLTYAIFNYNQVVFPQARCVGVDGDMAQAFETMA-------------
>tr|F3MLG8|F3MLG8_LACHE Uncharacterized protein OS=Lactobacillus helveticus MTCC 5463 GN=AAULH_07001 PE=4 SV=1
------------------------------DELIKHVKEADAIIVGAGSGMSNAAGMDFFMKHKYFYDKYHFEGIFNGFYTRDSKEEHWAFMLESLKMIL
-NIPPQKPTYEYLKKLIG--NKPVHFVTTNQDTLFKKF-FPQVSEIQGSWDYYQASNSTDLYSTKKPTELIPKSDING--SELILGARGP-QFLEEHQKW
NKFMSEKILFLEMGVGRMT-PMIQEPFWKQLKNSFYININPKDAMTNPDRSLLIGDDINEVLKEVS-------------
>tr|A0A0R1L3J0|A0A0R1L3J0_9LACO Uncharacterized protein OS=Lactobacillus futsaii JCM 17355 GN=FC88_GL001897 PE=4 SV=1
------------------------------NELVNQIKNADAIVVGAGSGMSNAAGMNFFLKELYFHEKYHFEGIFNGFYNHDSEEEHWAFILKALKMIF
-SIPPQKQTYEYLKTLLS--DKPVHVITTNQDMIFKKF-FSNVSEIQGSWSLFQSSNQTDLYPTASSLDLIPKSQVDG--AELIPWVRGP-EFLEEYQKI
NKFINEKILFLEMGVGRMT-PMIQEPFWENLPQSFYININPKDALTSPERSLLIDEDINETLKKAA-------------
>tr|A0A0R1TTB8|A0A0R1TTB8_9LACO Uncharacterized protein OS=Lactobacillus equi DSM 15833 = JCM 10991 GN=FC36_GL000011 PE=4 SV=1
------------------------------NALLRQINEADAILVGAASGMSTAAGMDFYNTERYYADKYGFHGIFNGFYNHESEEEHWGFYLAALDMIL
-NLPAQKPTYKNLKRLLK--DKDYHIMTTNQDTLFFQD-FPKISEIQGSWNYFQSERSSDLYSTRQPKTAIPYSPVNG--AKLIPWARGP-EFLEEHKKI
NQFLGQKILFLELGVGRMT-PMIQEPFWENMKQAFYVNINPKDALTHPDRSLLIHEDINNVLAAAV-------------
>tr|A0A0P0DW91|A0A0P0DW91_9LACO Sir2 silent information regulator family NAD-dependent deacetylase OS=Lactobacillus gallinarum GN=AO203_02930 PE=4 SV=1
------------------------------DELIKHVKDADAIVVGAGSGMSRATGLAFYMDNKYFAKKYGFNGLFQGFYNRESEEEHWAFLLELYKMMN
-EIPPQKPTYEYLKNLIG--DKPVHYVTTNQDMLFTKY-FPEVSEIQGSWHYFQSSRMSELYPTKGPSKLIPKSDVDG--APLIPWVRGP-EFLEEHAKW
NKFMGEKILFLEMGVGRMT-PMIQEPFWEQMPDSFYININPQDARTNPDRSLLIGEDINEALKEAN-------------
>tr|A0A0R1YDN4|A0A0R1YDN4_9LACO Sir2 silent information regulator family NAD-dependent deacetylase OS=Lactobacillus hamsteri DSM 5661 = JCM 6256 GN=FC39_GL0004
------------------------------QELINQVNQADAILVGAGSGMSNAAGMNFFMKHKYYYDKYYFNGIFNGFYTRDSLEEKWAFQLIAWDMIF
-NIPPQKPTYTYLKTLLQ--NKPTHIITTNQDGLFKRY-YPQISEIQGSWYFMQSKDSNDLYDAKEDKKYIPTSPING--STLQVWARGP-EFLEEYQKV
NKFLGKKILFLEMGVGRMT-PMIQEPFWEKMKNSFYININPKDALTNPDRSLLIGDDINEVLKQAA-------------
>tr|C2EN98|C2EN98_9LACO Sir2 silent information regulator family NAD-dependent deacetylase OS=Lactobacillus ultunensis DSM 16047 GN=FC57_GL000186 PE=4 
------------------------------DELLKQVKAADAIVVGGGSGMSNAAGMDFFMKYKPYYDKYHFEGIFKGYYTPDSKEEKWAFMLYAYKLIF
-NEPPQKPTYEYLKTVIG--NKPVHYVTTNQDGLFKKY-FGAVSEIQGSWSFMQSSNETDLYDAKKDSQYFPKSPIND--AELIAWVRGP-QFLEEYKKF
NKFLGEKILFIEMGVGRMT-PMIQEPFWDQMKDSFYININPKDALTNPDRSLLIGDDINEVLKEAA-------------
>tr|A0A0R1X6A5|A0A0R1X6A5_9LACO Uncharacterized protein OS=Lactobacillus panis DSM 6035 GN=FD32_GL000856 PE=4 SV=1
------------------------------ENVVAHINNADAIIIGAGSGMSNAAGMNFFMKYRDFYQKYHFEGIFKGFYNRASEEERWAYLLKMLKMVS
-TIPPQNDVYNYLKTIVH--NKPYHIITTNQDMLFKKF-FPHVSEIQGSWGFFQSKNATDLYPINRPTTLIPKSKVDG--TPLIPWVRGP-EFLEEYEKA
NRFLLKKVLFIEIGVGRMT-PMIQEPFWENLAHSFYINFNPQDALTNPDRSLLISTDTAKALQSIA-------------
>tr|G5JNY6|G5JNY6_STRCG Uncharacterized protein OS=Streptococcus criceti HS-6 GN=STRCR_1517 PE=4 SV=1
------------------------------TTLLEKIQQADAILVGTGSGMSAATGLNFYNATRYYADKYGFNGMFEGFYTHHTEEEQWGYYLGALDMIL
-NLKAPKPTYAYLKHLLG--DKPFHIVTTNQDTVAFRY-FPVISEIQGSWHYFQSQHYSDLYSTKIPSQYIPKSKVDG--SPLIPWARGP-EFLEEHQKI
SCFLGQKILFIELGVGRMT-PMIQEPFWENMPDSFYVNINPKDALTHPERSLLIHDDINTILEEAV-------------
>tr|A0A0R1PIR8|A0A0R1PIR8_9LACO Uncharacterized protein OS=Lactobacillus frumenti DSM 13145 GN=FD27_GL000003 PE=4 SV=1
------------------------------ETVVTHINDADAIIIGAGSGMSNAAGMDFFMKYSDFYQKYHFEGIFKGFYNRESQEERWAYLLKMLKMVS
-TIPPQNRVYDYLKTIID--NKPYHIITTNQDMLFKKF-FPHVSEIQGSWGYFQSKNSTDLYPTASPTELIPKSEVDG--TPLIPWVRGP-EFLEEYEKA
NQFLLKKILFIEIGVGRMT-PMIQEPFWENMPQSFYINFNPRDALTNPDRSLLINSDTAKALQNIS-------------
>tr|D1PQM1|D1PQM1_9FIRM Uncharacterized protein OS=Subdoligranulum variabile DSM 15176 GN=SUBVAR_06690 PE=4 SV=1
------------------------------EVLLDKINGAEAILVGAAAGMSASCGFDFFERYGDFHRKYGFVGAFNGFYYNPSPEAHWAFLARMGYMEY
-ECPTGKP-YYDLMRLLS--GKNFHIMTTNQDFQFTRV-VPKLSAIQGDSRYYQCSRCHDIYWNKEPAELIPRCPRCG--AEMEPWVRGY-TFLEEYRKI
QEFLERKILFLELGVGRMT-PMIQEPFWNYLPQAYYITINPKDALLPQQKGWAIQEDIAAVLRDAV-------------
>tr|A0A0M5JR18|A0A0M5JR18_9BACI NAD-dependent protein deacetylase OS=Bacillus sp. FJAT-18017 GN=AM500_18280 PE=4 SV=1
------------------------------DTLLEKIESADAIVVGGAAGMSEAIGHSFFLKHGKFADKYGIKNLFEGFYYRSTREERWAYLATEIKFIY
-DAEAGHP-YLDLSQLLQ--GKNYFIVTTNQDAQFSKT-FPKVSPIQGDLRYFQCGSCHDVYFNKEPTELIPFCPKCG--QEMEPWVRSY-VFLEELIKY
NEFLDKKVLFLELGVGTMT-PMIKEPFWNYWPDAYYITINPKDALLPRDKGLAIHKDIAVVLQDAL-------------
>tr|A0A0R1KMS7|A0A0R1KMS7_9LACO NAD-dependent protein deacetylase, SIR2 family OS=Lactobacillus coryniformis subsp. torquens DSM 20004 = KCTC 3535 GN=FC16_GL00
------------------------------QKAVTALTNADYIVVGGASGMSAASGPDWYLKKKTFENKYHAGSLWRNYYLEASRGDYWGFKISLAHFVL
-HEPIYQP-YADLRSILK--TKSFDVVTTNQDGQFSKA-FPDVAIIQGDWSYFQCSTCHDVYPSTAPEDLIPRCPQCG--AEMHEWVRGY-HFLEQYAKY
QKFVDKRTVFLELGVGMMT-PMIKEPFINYNPHATYITINPKDALVPPARGIPIKADLATVLAVLK-------------
>tr|A0A0J0HBY6|A0A0J0HBY6_ENTAS Uncharacterized protein OS=Enterobacter asburiae GN=ABF77_12875 PE=4 SV=1
------------------------------ATIYHKLQGADAILVGGASGMSTANQHDFFRDNSEFQRNYGIRNLCDALYYRPSSEERWAYLAKHGTLMF
-DEPPGQT-YIDLHTLIK--DKNYFIITTNQDMQFSKL-FPKLCYPQGTSHWLQCGQCHDVYPSEPPTALLPRCPRCG--AEMEPWFRSP-VFLEYMDRY
QDFIHKKIVLLELGVGPMT-PNIKHPFSIYWANAFLVRINKGEPPTHDEKTITLDCDIAQVLSDLV-------------
>tr|T5LBZ7|T5LBZ7_STEMA Uncharacterized protein OS=Stenotrophomonas maltophilia MF89 GN=L681_00920 PE=4 SV=1
------------------------------ATIARKLDEADAVLVGGASGMSTANQHDFFRDNGEFRDAYGIRNLCDALYYRQTSEERWAYLSKHGALLY
-DEPPGKT-YVDLHALIK--DKNYFIVTTNQDLQFSKL-FPKLCYPQGTSHYLQCGICHDVYPSEDPKTLIPKCPRCG--AEMEPWFRSP-VFLEGMRRY
QDFIHKKILLIELGVGPMT-PNIKHPFSVLWPQAFLLRINKGELPTHANKAITLDADIAQVLHDLR-------------
>tr|D4LRG0|D4LRG0_9FIRM NAD-dependent protein deacetylases, SIR2 family OS=Blautia obeum A2-162 GN=CK5_19880 PE=4 SV=1
------------------------------RTLLDKLNSAEAILVGAAAGMSASCGYNFFQKYGDFHKKYGFTGAFNGFYYHPSPEAHWAFLVRMGYMEY
-ECPTGQP-YYDLMELLE--GKNYHIMTTNQDFQFTRV-VSKLSAIQGDSRYYQCSRCHDIYYNKDPAKMIPRCPKCG--AQMEPWVRGY-TFLEEYRKI
NEFLEKKILFLELGVGRMT-PMIQEPFWNYLPKAFYITINPKDALLPEQKGLAIKEDIALVLQEAV-------------
>tr|B3JN84|B3JN84_9BACE Uncharacterized protein OS=Bacteroides coprocola DSM 17136 GN=BACCOP_03396 PE=4 SV=1
------------------------------DLLKKKIDEADAIVVGGASGMSAASGFVFYKMLGGLAEKYNIHNYFDLFYDRLSRGELWASMLRATRYIY
-ECYTGET-YKDLAKLLQ--GKNYYIATTNQDAQFFRV-FPKITRIQGDNRYWQCSRCHDIYYNKEPDELIPRCPHCG--EELAPWVRSH-TFLEEMKRY
LDFLRRKVLFLELGVGMMT-PMIKEPFMNYFPDAFYATVNPQHAIVPKKKSLAISDDIAVTLKKLL-------------
>tr|A5ZR51|A5ZR51_9FIRM Uncharacterized protein OS=Blautia obeum ATCC 29174 GN=RUMOBE_01478 PE=4 SV=1
------------------------------SFLAEKIRQADAVLIGGGSGLSSAAGYNHMEECQDFKEWYGLKSPFDGFYYCSSPEQQWAYYARYIQSM-
-WDAPTGQPYYDLRDIVA--EKEVFVLTTNIDMQFERI-FQRICDYQGNSGYVQCSQCHDIYSNVETSELLPRCNECG--RIMVPWVRDDT-FLEGVRRY
ENFLDKNVVLLELGVGEMT-PSIKLPFWEYNEKVFYACLNQKKSSTPEDKGIYIAGDLAETLRDLK-------------
>tr|D1PQM0|D1PQM0_9FIRM Uncharacterized protein OS=Subdoligranulum variabile DSM 15176 GN=SUBVAR_06689 PE=4 SV=1
------------------------------EWLAQQIARADAVVIGGGSGLSSAAGYDHLSGPEKFRKYYGFTSPFAGFYHCSSYGEQWGYYSQYIRAM-
-WEAPTGRPYLDLKEIIG--NKPVFVLTTNADGQFFRV-FPKICAFQGDFGYCQCSQCQDLWENRDPENAVPRCPDCG--RVLVPWVRDDT-FLENLTRY
HDFLGKRLLLLEVGVGEMT-PSIKLPFWQANEMVFYACMNQKESDVPEDRGLYIQGDLAETLAALR-------------
>tr|D7GTI8|D7GTI8_9FIRM NAD-dependent protein deacetylases, SIR2 family OS=butyrate-producing bacterium SS3/4 GN=CK3_14210 PE=4 SV=1
------------------------------QELAERIAQADAVVIGGGSGLSSAAGYDHLSEAAPFREQYGFTSPLAGFYHCSSYGEQWGYYSQYMRFM-
-WEAPTGQPYLDLQAFLA--DKSVFVLTTNVDQQFFRV-FPQICAFQGDFSYCQCSQCRDIWENREPEEAVPRCPDCG--RMLVPWVRDDT-FLESLHRY
HRFLDKKVLLLELGVGEMT-PSIKLPFWEANENVFYACLNREVSHRPEGRSLYLQGDLAETLAALR-------------
>tr|R6CEM8|R6CEM8_9BACE NAD-dependent protein deacetylase SIR2 family OS=Bacteroides sp. CAG:530 GN=BN697_01754 PE=4 SV=1
------------------------------DILKSKIEEADAIVVGGASGMSAASGFRFFRQMGSLREKYGFRNMFDGFYHPTTKGEHWALKLRTIKYVY
-ECETGET-YTDLAELLE--GKNYYIVTTNQDAQFYRV-FPRITRLQGDWRYFQCKDCHDIYYNKDPKADIPRCPVCG--GEMDVWVRSR-EFLEELQRY
MSFLRRKMLFLELGVGMMT-PMIKEPFMNYWPHAFYVPINPQHAIIPKGKSLAVNDDIAFALKEIL-------------
>tr|F0R2V8|F0R2V8_BACSH NAD-dependent protein deacetylase, SIR2 family OS=Bacteroides salanitronis (strain DSM 18170 / JCM 13567 / BL78) GN=Bacsa_1958 
------------------------------DLLRKKIDEADAIVVGGASGMSAASGFVFFRQLGGLAKKYDRHNMFDLFYDRPSQGEQWALMLRTIRYVY
-ECHTGET-YTDLAELLE--GKNYYIVTTNQDAQFYRV-FPHITRIQGDWRYWQCSQCHDIYDNHTPDKLIPRCPRCG--RPMAPWVRSR-EFLQEMKRY
YEFLDRKMLFLELGVGMMT-PMIKEPFMNYWPKAFYATLNPQHALVPKDRSLAIGDDIAVTLKQLL-------------
>tr|A0A0D0S6L0|A0A0D0S6L0_9FIRM TWA4_scaffold00001, whole genome shotgun sequence OS=Lachnospiraceae bacterium TWA4 GN=P261_00681 PE=4 SV=1
------------------------------QQVLDWIEEADAVVVGGASGLSTANGFDYFEKYGDFGKIYNEPSAWQLLYHRNCDEERWAYMARSGAVM-
-LDLEAGQTYKDLYELVK--DKDHYVITTNQDAQFSKV-FDKIFTIQGDAHWMQCSECSEIYPSEEKTEDVPHCPKCG--AVMEPWVKSFI-FQYEAEKY
KAYLNDKVLFLGLGIGRMT-PEIKHPFMNYWPDARCAFLNLGEPEPIKDKSVALNVDILETLQEMV-------------
>tr|S0F720|S0F720_9BACE Uncharacterized protein OS=Bacteroides coprophilus DSM 18228 = JCM 13818 GN=BACCOPRO_01374 PE=4 SV=1
------------------------------DLLRKKIDEADAIVVGGASGMSAASGFKFFRRIGSLEQKYGFHNFFDGLYDRHTRGEHWAMLLRVAKYIY
-ECETGGT-YKDLAELLR--GKNYYIATTNQDAQFFRV-FPRITRIQGDWRYWQCKRCHDIYYNKEPDELIPRCPHCG--GVMDAWVRSH-TFLQEMQRY
MDFLNRKTLFLELGVGLMT-PMIKEPFMNYWPHAFYATLNPQHALVPKKKSLAISDDIAITLKQLL-------------
>tr|C7N0U1|C7N0U1_SLAHD NAD-dependent protein deacetylase, SIR2 family OS=Slackia heliotrinireducens (strain ATCC 29202 / DSM 20476 / NCTC 11029 / RHS 
------------------------------KAFAHMVEQADCILVGAASGLSAAGGGDFYRAYGKFAEKYGFQGAFAGMMHPETAEERWGYLATFLNTTL
-SVPVRQP-YVDLDAVIR--DKEFFILTTNQDTQFMKL-YPKVAEIQGDHRFFQCQHCTDVWDATEPADLVPRCPHCG--GEAFPWVRGYGNFLQQYRKV
SDWLQEKVLFIELGVGRMT-PAIQEPFWASLPQASYVGINNVTQFLPEDRGIAIRGDIAEVLTDVR-------------
>tr|A0A0R1SCI3|A0A0R1SCI3_9LACO NAD-dependent protein deacetylase, SIR2 family OS=Lactobacillus versmoldensis DSM 14857 = KCTC 3814 GN=FC27_GL000317 PE=4 SV=1
------------------------------KILAEKIEEADHIIIGGASGLSAAGGGDFFKKYGKFEQKYDLNGAFSGMTYPKTREEYWGYLATFLNTTL
-HAEVRKP-FKDLQAILQ--GKDYFILTTNQDTQAIKA-FPKVAEIQGDHRFFQCSNCTDVWDAVKPTDMIPKCPNCG--AEAFPWTRGYGNFLEEYQKI
SDDVDDHLLFIELGVGRMT-PMIQEPFWATLDNTYDVMVNRDYQFLPKDKGQAIKADIDQVLDDVR-------------
>tr|A0A0R1SLM4|A0A0R1SLM4_9LACO NAD-dependent protein deacetylase, SIR2 family OS=Lactobacillus versmoldensis DSM 14857 = KCTC 3814 GN=FC27_GL000334 PE=4 SV=1
------------------------------KILAEKIKEADHIVIGGGSGLSAAGGGDFFRKLGKFADKYGFDGAAAGWSYPSTREEFWGYLATFLYTTQ
-HAPIQKP-YLDLQKILK--GKDYYVLTTNQDTQTVKA-FPRVSQIQGDQRFFQCSNCNDVWDAVKPTELIPKCPTCG--AEAFPWNRGFGNFLEEYKKV
SDDIDDKLLFIELGVGRIT-PMIQEPFWAALDGAYDVMINRDYQFLPE-------------------------------
>tr|A0A0R1KKH8|A0A0R1KKH8_9LACO NAD-dependent protein deacetylase, SIR2 family OS=Lactobacillus paralimentarius DSM 19674 GN=FC78_GL001053 PE=4 SV=1
------------------------------NILAEKINEADHILVGGASGLSAAGGGDFFRKYGKFAEKYGIKGAFSGMQYRPSREEYWGYLATFLHTTQ
-HAEIRKP-YKDLQAILQ--DKDYFILTTNQDTQAIKA-FPKVAQIQGDHRFFQCSACSDVWDAVKPTELIPRCPNCG--AEAFPWVRGYGNFLEEYKKV
SDDVDNHLLMIELGVGRMT-PMIQEPFWAGLEGSYDVMINRDHQFLPEDKGQAIKGDISQALADVR-------------
>tr|A0A0R1ITJ3|A0A0R1ITJ3_9LACO NAD-dependent protein deacetylase, SIR2 family OS=Lactobacillus farciminis KCTC 3681 = DSM 20184 GN=FC68_GL000232 PE=4 SV=1
------------------------------QILADKIKEADHIIVGGASGLSAAGGGDFFRKYGKFAEKYGIKGAFSGMQYPPSREEYWGYLATFLHTTQ
-HAEVRKP-FRDLQEILK--DKDYFILTTNQDTQAIKA-FPKVAQIQGDHRYFQCSQCSDVWDAVKPTELIPRCPNCG--AEAFPWVRGYGNFLEEYQKI
SDDVDDHLLLIELGVGRMT-PMIQEPFWGGLDGAYDVMINRDYQFLPEDKAQAIKGDISQVLDDVK-------------
>tr|A0A0R1K596|A0A0R1K596_9LACO NAD-dependent protein deacetylase, SIR2 family OS=Lactobacillus alimentarius DSM 20249 GN=FC67_GL000762 PE=4 SV=1
------------------------------KILADKIKEADHIVIGGASGLSAAGGGDFFRKLGKFAKKYGFKGAAAGWSYPPTREEYWGYLATFLYTTQ
-HAEIQKP-YRDLQKILK--GKDYYFLTTNQDTQGVKA-FSRVSQIQGDHRFFQCSNCNDVWDAVKPTEMIPRCQNCG--AEAFPWTRGFGNFLEEYQKV
SDDIDDKLLFIELGVGRVT-PMIQEPFWAGLDGAYDVMINRDFQFLPEDKGQAIKGDIAQALDDVL-------------
>tr|R9WE46|R9WE46_LACRE NAD-dependent protein deacetylase, SIR2 family OS=Lactobacillus reuteri I5007 GN=LRI_0117 PE=4 SV=1
------------------------------QLFAQKIKEADHIIIGGASGLSAAGGGDFYKKHAKFYEKYGFKGAFAGMRHHESREEFWGYLATFLNTTL
-HAEIRQP-YKDLQEILK--DKDYFIVTTNQDTQAIKA-FPKVAQIQGDHRFFQCSICTDVWDAVKPTEMIPRCPHCG--AEAFPWVRGYGNFLEEYQKI
SDDINDQILFVELGVGRMT-PMIQEPFWANLPNTFDVMVNKEYQFLPENKGVAIKGDITQVLDDVK-------------
>tr|A0A0R1Y6G2|A0A0R1Y6G2_9LACO Uncharacterized protein OS=Lactobacillus pontis DSM 8475 GN=FD34_GL001133 PE=4 SV=1
------------------------------KVFAEKVKEADHIIVGGASGLSAAGGDDFYQQAKRFYEKYHFTGAFAGMRHRSSRGEFWGYLATFLHTTL
-HAPIREP-YKDLQAILR--DKDYFILTTNQDTQAIKA-FLKVAQIQGDHRFFQCSQCTDVWDATEPDAMIPRCPHCG--AEAFPWVRGYGNFLEQYQKI
SDDLDQHLLFLELGVGQMT-PMIQEPFWANLPGAYDVMVNRDYQFLPQDKGVAIKGDIAKVLKDVR-------------
>tr|A0A0R1J8Y7|A0A0R1J8Y7_9LACO Nad dependent acetylase OS=Lactobacillus tucceti DSM 20183 GN=FC72_GL001450 PE=4 SV=1
------------------------------KKFSKMFNDAEYVVIGGASGLSAAGGGDFFYENGKFSKKYGFKGAFAGMRYPPNRETYWGYLATFLNTTL
-NASIRQP-YQDLAAILN--DKDFDIVTTNQDTQFIKS-FDKVSEIQGDHRFFQCSNCTDVWDATEPTDLIPRCPRCG--AEAFPWVRGYGNFLEEYAKI
SNALGSKTLFIELGVGRMT-PMIQEPFWTYLSNANYISVNRDSAFLPENKGLAIQNDIAKVLHDVR-------------
>tr|A0A0Q1BE17|A0A0Q1BE17_9FIRM NAD-dependent protein deacetylase OS=Lachnospiraceae bacterium TF01-11 GN=APZ18_06455 PE=4 SV=1
------------------------------QEFVRRVQEAECIIVGGASGLSAAGGGDFFREHGKFADKYGFKGAFSGMMHRSTRNEHWGYVATFLNTTQ
-NAPIREP-YLDLDRILQ--GKDFHILTTNQDTQFVKI-YPKVSEIQGDHRFFQCSQCQDTWDAVQPDELIPHCPHCG--AEMFPWVRGYGNFLQEYEKI
SKYIDRKILLIELGVGRMT-PMIQEPFWKNLKDAYYISVNSEYQFLPEDKGIAILGDIGTVLKDLR-------------
>tr|A0A0D0S6K2|A0A0D0S6K2_9FIRM TWA4_scaffold00001, whole genome shotgun sequence OS=Lachnospiraceae bacterium TWA4 GN=P261_00671 PE=4 SV=1
------------------------------KEFKKQIKEADCVIVGGASGLSAAGGGDFYRKYGKYAKKYGFKGAFAGSFYQSDPAEKWGYLATFLHTTQ
-NAEIRKP-YLDLDELLK--GKEFFILTTNQDTQFVKL-YPKVAQIQGDHRFFQCSRCSDTWDSVRPTDMIPRCPHCG--AEAFPWVRGYGNFLQQYQKI
TDYIDEKILFLELGVGRMT-PMIQEPFWERLPQTHYISLNDQYDFVPEDRAMAIKGDIATILENAL-------------
>tr|R7CSM4|R7CSM4_9FIRM NAD-dependent protein deacetylases SIR2 family OS=Dialister sp. CAG:357 GN=BN625_00424 PE=4 SV=1
------------------------------DRLVQEIRDADCIIVGGASGLSAAGGGNFFKKYGKFEEVYHFNGAFDGMFRHNDRAAFWAFLATFLHTTL
-TAPIRAP-YHDLDALLK--GKDFFVITTNQDTQFIKL-YPKVAELQGDYRFFQCASCQDTWDAVQPKGMIPRCPHCG--GEAFPWVRGYGNFLQQYEKA
SSYIDAKILFIELGVGRMT-PMIQEPFWQMLPHARYIGVNNQFDFLPRDKGMTILGDIAEVLTAAV-------------
>tr|D7GTI7|D7GTI7_9FIRM NAD-dependent protein deacetylases, SIR2 family OS=butyrate-producing bacterium SS3/4 GN=CK3_14200 PE=4 SV=1
------------------------------NRLVQEVKEADCVVVGGASGLSAAGGGDFYRKYRPFAEKYHFKGAFAGMMHPETREEYWGYLAAFLHTTQ
-IAPVRHP-YLDLDALLK--GKDFFILTTNQDTQFVKL-YPKVAEIQGDHRFFQCAACTDTWDAVKPTDLIPRCPHCG--GEAFPWVRGYGNFLQQYEKI
SRYVDSKILFLELGVGRMT-PMIQEPFWNLFPHARYIAINDKYDLLPKDKGMTIVADIAQVLRDAR-------------
>tr|A0A0K2LCP5|A0A0K2LCP5_9LACO NAD-dependent protein deacetylase OS=Lactobacillus heilongjiangensis GN=JP39_06135 PE=4 SV=1
------------------------------EQFSKMLNDAEYVVIGGASGLSAAGGGDFFYETGKFSEKYGFKGAFAGMQYPPNRETYWGYLATFLHTTL
-NAQIRQP-YQDLAAILQ--DKDFDIVTTNQDTQFIKE-FDTVSEIQGDHRFFQCSNCTDVWDATKPTDLIPHCPHCG--AEAFPWVRGYGNFLEEYTKI
SNALGAKTLFIELGVGRMT-PTIQEPFWTYLPNASYISVNHDNAFLPENKGLAMQNDTAKVLHDVR-------------
>tr|V6LEA6|V6LEA6_9EUKA Sir2 family protein OS=Spironucleus salmonicida GN=SS50377_17576 PE=4 SV=1
--------------------------SFLNSSLAEQIIKADFVLIGAGAGFSVDSGLKTFRDIAPFYQQLTYDDLCDPLWLKRNYLIFYGFWGTCYNAYQ
--THKPHAGYQNLISFLQSNSKDFFIYTSNIDGFFTNFDTEQLYEFHGQLRYWQCSGCSQIYTFNEDLTCLPRCCFCE--QLLRPHVLMFEDFSDDTNKE
DKQLTQNLLILELGCGLKV-PSLRIEFERRTQKSVLLRINPSEVG----------------------------------
>tr|A0A094AR01|A0A094AR01_9PEZI Uncharacterized protein OS=Pseudogymnoascus pannorum VKM F-3557 GN=V490_01341 PE=4 SV=1
----------------------------------HLIKSKRRIVAIIGAGVSTAAGVPDFSSNTDRFKKYSVKDLFDEAMLNTE-QSVNAFKDVLHKA--
AESAHPTRFHHLLATLAEQ-KQLLRLYTQNIDDLDTRLAPPQTIQLHGSVSKMICPTCHEHVGFKPELFTIRRSDRLA--GNFRPTITLYQDSFEKIQQV
IDLKRKPDLLIVAGTSLKIKAVKKMVELFHDPSGSTVWINMKDEPQSNPWDLKINSNCER-------------------
>tr|A0A093ZL99|A0A093ZL99_9PEZI Uncharacterized protein OS=Pseudogymnoascus pannorum VKM F-4246 GN=V492_00115 PE=4 SV=1
----------------------------------DIFRQKKRIIIIAGAGISASAGIATFQDLPV-----KGRDVFSINSYNDDASTMCRMYSS----I-
-RSASPTQFHHVIEELAKE-GRLHRLYTQNIDGLDTQLPSPTAIQLHGDLKTVKCQGNPTHLSFNPREGSLPCCTICKNIPLMRPRVWLYDDYDYAMVSA
SDLRAKPDAVIVVGTALKVESRRKFAIDVRKCGGLSAWINLKPPSKQKCFDIVIKGDSDTIA-----------------
>tr|M7P4X8|M7P4X8_PNEMU Uncharacterized protein OS=Pneumocystis murina (strain B123) GN=PNEG_02678 PE=4 SV=1
------------------------------SKIIDIIEKSKKSVVITGSGISYDKKISGFSSSDGLYKFIKAKDLLDSLMFRDETSIFYSFMAELRTLIL
--SAKPMNTYKFIKILRDR-SSVLRCYTENIDGLGLQEELNNMTESNEDVNKLKCMICGIKCDYERLLRNGPVIEKRGKIGFLRPGIVLYGNTHPILAET
SDVKKWPDLLLIIGISLKIIAINSLIKDIHSNGGKVIFVNRTEPCNKGIIDWYVEADSDEWIEELK-------------
>tr|A0A0F7VGC1|A0A0F7VGC1_9EURO Uncharacterized protein OS=Penicillium brasilianum GN=PMG11_04546 PE=4 SV=1
------------------------------FKARTWLKQADTLIISAGAGLSAAAGL-DYTSPT-LFAKHKLYDVFGYTGW-DSPAEKWGYYFTHLDMVR
--RWPESDVYRTLRELTSRFGERWFVRTSNADGLFVKNGFGRVATPQGGYRFLQCLRCRHGLETKPDERMVPKCEFCG--GEMTLCVSYFDAAPFGWREL
ESEESGSVVILELGVGLNTPAVLRWPNEDSSQRFRLIRVGMDAAGVELELAVGISGDIKAALDALI-------------
>tr|A0A0D9MEH3|A0A0D9MEH3_9EURO Uncharacterized protein OS=Penicillium solitum GN=U727_00431100151 PE=4 SV=1
------------------------------TKARTWINEASNLIISAGAGLSAATRL-DYTSTA-LFDKHRLYDVFGHVDW-DSPGQKWGYYFLHLNMVR
--SWPTSPVYNTLRELVGRFPSKYFIRTTNADGFFLKNGFEFISTPQGQYRFLQCFNCRPDFPSDPDSTKIPHCPFCG--GEATICVHYFNAGPFAWKGL
DGYGSATTVILELGVGLNTPGVLRWPNENISRGFRLIRVGMGASGVELELAVGVSADIKTALDLLT-------------
>tr|G4YNX2|G4YNX2_PHYSP Putative uncharacterized protein OS=Phytophthora sojae (strain P6497) GN=PHYSODRAFT_471191 PE=4 SV=1
------------------------------QSAARAIQDADYLLVAAGAGLSAAAGL-DYTSEA-VMKKFTMYHQIGYTNW-DEPLM-WGWLFKHISLVR
F-GWVPAPTYDYVKNIV-AFHGSAFIKTSNADGMFEQEGFKSIYLMQGEYGRIQCSKCSEDWSARPDPAEIPRCPKCG--GKMFLLLDSFLQSALEYANV
LDRDGKKLAILEVGAGFNTPGVLRLPNERY--GVQLVRVNPDYP-MQS--GVGVAEDANAVLEYIS-------------
>tr|G5ABJ5|G5ABJ5_PHYSP Putative uncharacterized protein OS=Phytophthora sojae (strain P6497) GN=PHYSODRAFT_252048 PE=4 SV=1
-------------------------------GARVVIQDADYLLVSAGAGLSASAGL-DFRSEA-VMKMFTLYNFIAFRDW-DEALM-WGFYFKNASMIW
F-DWMR------IQDIV-QFEGSSFVQTTNVDGLFQQEGFKSVFVMQGDFGRILCAKCSQEWDIKPDPADLPKCPKCG--GRTSAFLDTFIDSGVEYDRV
MEQYGKKLVILEVGIGFNTPGVLRIPDEQL--GVQLVRVNQESP-IQC--GVEVPEDATDVLDYIA-------------
>tr|A0A0L0DID1|A0A0L0DID1_THETB Appr-1-p processing domain-containing protein OS=Thecamonas trahens ATCC 50062 GN=AMSG_00941 PE=4 SV=1
------------------------------ARVAAALAAADGVLVTCGAGLSAAAGV-DYTSAE-VHARFNMYQYIGGAPR-DPAVK-WGYLARQVKEVR
F-GTDMHDTYDRLRTLV----LPYFCLTSNVDGLLHRLGFRRVVERQGSYALMQCLEECSSWPSEPTSAPPPVCPVCG--SNVFLNVAWFDERPRALDGF
A--VDDNLIVLEIGVGYNTPTVIRRPNEQA-RGATLIRINTDHA-AAIS-TVLVPMDANAFLRAIA-------------
>tr|M3K6U0|M3K6U0_CANMX Uncharacterized protein OS=Candida maltosa (strain Xu316) GN=G210_2210 PE=4 SV=1
------------------------------QEARQWLDDADYLIISAGAGLSASEGL-DYMSKE-LFHRETLYGTIGF-PW-PTKLDFWNFFIYHYDNLY
N-KWPQTATYQKLLNIKKF--QDSFVITTNADGFFVKNGFNKVLTAQGNYYYIQCSKCRIDRPIKESTEDIPTCHFCG--SEMTMFLASFNEMIVNYTNV
VKS-NKKCVILELGVGLNTPSILRWPNENDANNFKLIRVGLGPSAIEID-TIVIDADVKQAVDLLS-------------
>tr|A0A0A6KWI9|A0A0A6KWI9_CANAX Uncharacterized protein OS=Candida albicans P75010 GN=MGE_02129 PE=4 SV=1
------------------------------NKAHSWLQEADCLIISAGAGLSASEGL-DYTSKE-LFQRESLYGTIGY-PW-PTKLDFWNFFVYHYINLY
K-KWGKTDTYQRLLNLSRF--EDSFVITSNADGFFVKNGFDRVLTVQGNYANIQCSKCRSDRSMEEAKDQIPRCEYCG--SEMTVFLDYFNPAIVNYSGI
VRT-NQKAVILELGVGLNTPSVLRWPNEDEPENFKLIRVGTGPSSADDE-TVVINGDIKKVVQLLN-------------
>tr|C5M797|C5M797_CANTT Putative uncharacterized protein OS=Candida tropicalis (strain ATCC MYA-3404 / T1) GN=CTRG_01729 PE=4 SV=1
------------------------------DQAKKWLQDADSLIISAGAGLSASEGL-DYSSKE-LFHKESLYETIGF-PW-PSHVEFWNFFIYHYINLY
K-KWPRTTSYQHLLKLSEY--QDSMVLTSNADGFFVKNGFERVFTIQGNYANIQCSICQPDRPMEESSDDIPKCQFCG--SEMTMFLDHFNTEIVDYRAS
LAS-KKKVVILELGVGLNTPSVLRWPNEEEPEQFKLIRVGLGPSSINID-TVVINGDVKQVIGLLV-------------
>tr|B9WC14|B9WC14_CANDC Uncharacterized protein OS=Candida dubliniensis (strain CD36 / ATCC MYA-646 / CBS 7987 / NCPF 3949 / NRRL Y-17841) GN=Cd36_2155
------------------------------DKAKAWLQEADCLIISAGAGLSASEGL-DYSSKA-LFQRESLYGTIGF-PW-PSKLDFWNFFIYHYTNLY
K-KWGPNDTYQKLLGLLQF--EDSFVITSNADGFFVKNGFDRVLTVQGNYANIQCSKCRPDRSMDESKDQIPRCHYCG--SEMTMFLNYFNSAIVNYNRI
INT-NKKAVILELGVGLNTPSVLRWPNEDEPANFKLIRVGMGPSSVDNE-TVVINGDIKKVVQLLN-------------
>tr|A3LYE6|A3LYE6_PICST Uncharacterized protein OS=Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) GN=PICST_62714 P
------------------------------EVSKKLIQDTDYLIVSAGAGLSASVGL-DYSSNE-VFDKHRLYETIGH-QW-PSKLVEWSFWFHHYETVS
--RWPASESYQKLVRMLC---TNSFVITSNADGFFIKNGYKKVYSIQGNYYWIQCPICTQDRPMDADSSHIPRCENCG--HIMTMCLWKFNDTPMTYNKI
VRE-NQKAVLLEFGVGLNTPSVLRWPNEESENNFTLIRVGNGPSSVEYENFIVIDADASEVIDLLV-------------
>tr|W4HCY0|W4HCY0_9STRA Uncharacterized protein (Fragment) OS=Aphanomyces astaci GN=H257_00511 PE=4 SV=1
------------------------------AEAAALIRDSDFVLISAGAGLSAAAGL-DYTSPD-VFAKHTMYEFIGPQDW-TPALQ-WGYYFAQTNLVR
Y-QWQPTPVYTLLKALF----KNTFIHTSNADGLLEQQGFQRIYTAQGDYSRLQCLKCSQQWDIRPDSEAIPRCPKCR--GAMMLNVRWFIESAQ-YDDA
HTQRAKTLVVVEIGAGFNTPGVLRIPNEKE--GVALVRLNIHDH-VTS--GVGVSEDAAVALQVIM-------------
>tr|A0A017SFI1|A0A017SFI1_9EURO Appr-1-p processing enzyme family protein OS=Aspergillus ruber CBS 135680 GN=EURHEDRAFT_377284 PE=4 SV=1
------------------------------LKAQQWIKEADTLIISAGAGLSAATGL-DYTSPA-LFAKYRLYDVFGFQEW-ISPAQKWGYYFNHLNMVT
--TWPASLMYSALRQFTQRFE-RYFIRTSNADGFFAANGFNRITTPQGQYRYLQCFACRRDFLSEPDTSKIPRCEYCG--GELTICVDYFNPVRFAYEDT
ARL--SNTVILELGAGMNTPIVLRWHDEDRKGNVRMIRAGIGAAGADMEEAVGIEGGLDHLLDVLI-------------
>tr|W3XHW6|W3XHW6_9PEZI Uncharacterized protein OS=Pestalotiopsis fici W106-1 GN=PFICI_02841 PE=4 SV=1
------------------------------GRARDWLLSADAILISAGAGLSAADGL-DYTSPA-LFSKYTLYSVFGFSEW-PSEQHRWGYYFTHLNMVK
--SWPRSSMYTGLISWLNR--AEVHVRTSNADGLFLANGWDALSTPQGSYAVLQCLKCRPDAPSAPAPDKIPQCQFCR--GKMNICVNWFNERPFAWADT
R-GRGKRLVILELGVGQSTPGVLQWPNEDDGGKTLLVRVGLGVDAVELALATYIDGDIQALLSSLC-------------
>tr|A1CAU9|A1CAU9_ASPCL Appr-1-p processing enzyme family protein OS=Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1
------------------------------RKARQWIQEADALIISAGAGLSAAIGL-DYTSPA-LFKQHRLYDVFGFNGW-DSGNQKWGYYFQELNMVR
--CWPASSVYAQLLQLASGFG-DYFIRTSNADGLFVANGFRRVSTPQGQYRYLQCLACRRNFESAPDSSMIPGCKYCG--GELTLCVDYFNQAPFAYEQI
ASE-SKTTVILELGVGMNTPSVLRWHNEDE-PQVKLIRAGIGASGAHLEQAIGILGDLKEIIPCLT-------------
>tr|A2QSI2|A2QSI2_ASPNC Aspergillus niger contig An08c0280, genomic contig OS=Aspergillus niger (strain CBS 513.88 / FGSC A1513) GN=An08g10810 PE=4 SV=
------------------------------IQAKAWLAAADTILISCGAGISAATGL-DYTSTT-LFDRHRLYDTFGRRDW-PSESVRWGFYFSHLAMVR
--RWPRSSLYTSLLKWLSRFQDRVHVRTSNADGLFAAHGLAQLSTPQGQYAFLQCLECRPDFPSAPAQDKIPTCSFCG--GAMSICVDWFNERPFPWEAF
LTDLTRNVVIIELGVGLSTPGVLRWENEEEDGRVRLVRAGLGDAVVELALATSIEGDLQDVVRAIV-------------
>tr|A0A0I9ZKV6|A0A0I9ZKV6_GIBFU Phosphatase ous to the C-terminal domain of histone macroH2A1 OS=Gibberella fujikuroi GN=LW93_9188 PE=4 SV=1
------------------------------SLGRDWLASADAVLITAGAGLSAAEGL-DYHSRD-LFKKNSLYSVFGFNDW-PSEEHRWGYFFTHLNMVA
--NWSNTPTYQALILWLNF--QDAFVRTSNADGLFLANGWEQLSTPQGSYGYLQCLNCRVDVPSAPDSSKIPLCRFCG--SKMSICVSWFNQAPFEWTRV
L-REKKNLVVLELGVGMNTPGVLRWPNEDMDGRVKLIRVGMGPEAVEQDLSTCIQGDIGRAIPLLL-------------
>tr|C7Z089|C7Z089_NECH7 Putative uncharacterized protein OS=Nectria haematococca (strain 77-13-4 / ATCC MYA-4622 / FGSC 9596 / MPVI) GN=NECHADRAFT_4736
------------------------------ALAREWLDDADAVLVTAGAGLSAAEGL-DYHSRS-LFAENSLYSVFGYNDW-PSEEHRWGYFFTHLNMVS
--NWPKMPSYQALISRLKF--PDAHVRTSNADGMFLANGWQQLSTPQGSYAYLQCLECRVEVRSAPDSSKIPRCKYCG--AKMSICVPWFNQAPFEWSRI
L-REKKKLVILELGVGMNTPGVLRWPNEDSNGLVKLVRVGLGPEAVDQDLSTYVDGDISQVMPLLV-------------
>tr|A0A0P7BDV6|A0A0P7BDV6_9HYPO Uncharacterized protein OS=Neonectria ditissima GN=AK830_g1677 PE=4 SV=1
------------------------------EKARQWLESADAVLVCAGAGLSATEGL-DYTSSA-LFKKHTLYSVFGFTGW-PSEQDRWGYFFTHLNMVS
--TWPASPTYQTLISALNF--PDAHVRTSNADGFFLANGWEQLSTPQGSYAILQCIKCRPDVQSSPDPEKVPFCRFCG--SKMSICVAWFNEEPFEWNRV
L-REGKRLVILELGVGMNTPGVLRWPNEDSDGNVRLVRAGLGHEVVDLELATTIESDLKLIVAELL-------------
>tr|H3GM62|H3GM62_PHYRM Uncharacterized protein OS=Phytophthora ramorum PE=4 SV=1
------------------------------QRALEAVQGADYLLVAGGAGLSAAAGL-DYTSEA-VMKKFMMYSSIGYTNW-DEPLM-WGYLFNQISMVR
F-DWVRAPTYDYVKAIV-SFDGSAFIKTSNADGMFEQEGFKSLYIMQGEYGRIQCSGCAKDWDARPDPAGIPKCPRCG--GRMFLLLDSFLQSALEYAQA
LDHDGKKLAILEVGAGFNTPGVLRLPNERY--GVQLVRVNPEYP-MQS--GVGVAEDANTVLEYIS-------------
>tr|W2K7X0|W2K7X0_PHYPR Uncharacterized protein OS=Phytophthora parasitica GN=L917_18342 PE=4 SV=1
------------------------------QSALRAVQDADYLRVAAGAGLSAAAGL-DYTSEA-VMKKFVMYSSIGYTKW-DDALM-WGYLFKQISFAR
F-DWVRAPTYDYVKKIF-LFNGSAFVETSNADGMFEQEGFNSVYIMQGDYGRIQCLKCAQDWSSRPDPAGIPKCPRCG--GKMFLLLDTFLQSALEYAGV
LNRDGKKLAILEVGAGFNTPGVIRIPNERY--GVQLIRVNPEYP-MQS--GVGVAEDANAVLEYIS-------------
>tr|M4C5V0|M4C5V0_HYAAE Uncharacterized protein OS=Hyaloperonospora arabidopsidis (strain Emoy2) PE=4 SV=1
------------------------------RRALEAIRDADYLLVSAGAGLSAAAGL-DFGSED-VMKMLTLANMICFRRW-DDALK-WGFFFKNASIIR
Y-DWARAPTYAYLKSIA-RFEGSVFTKTSNGDGIFEQEGFSALFVMQGDFGLIQCAQCTPEWDIKPDPAGIPKCPKCG--GRMSTFLNTFLESGIDYTRV
MDQKSKKMVILEVGAGFNTPTVLRLPDERF--GVQLVRVNPEYP-MRC--GVGVTDDATSALDYIS-------------
>tr|A0A098DNW6|A0A098DNW6_GIBZA Uncharacterized protein OS=Gibberella zeae GN=FG04612.1 PE=4 SV=1
------------------------------QVAQDWLGSADAILVTAGAGLSAAEGL-DYHSRD-LFKKHSLYSVFGYNEW-PSEEYRWGYYFTHLNMIS
--NWSNTPTYQALIPWLDF--SDAFVRTSNADGLFLANGWGQLSTPQGSYAYLQCLNCRNDVPSTPDSSKIPICRFCG--SEMSICVSWFNQTPYNWSRI
T-KEKKKLVILELGVGMNTPGVLRWPNEDEQGLVKLIRVGIGAEAVEQDLSTFIQGDIQRVVPLLL-------------
>tr|Q0CUC7|Q0CUC7_ASPTN Putative uncharacterized protein OS=Aspergillus terreus (strain NIH 2624 / FGSC A1156) GN=ATEG_02707 PE=4 SV=1
------------------------------LKARSWLEEADFLIITAGAGLSAAIGL-DYTSQE-LFQKHRLYDVFGFTGW-ESPRQKWGYYFLHLDMVR
--KWPTSKLYKTLRTLANRFHSKYFVRTSNVDGQFVNNGFERISTPQGQYRFLQCYACRPDFPSGPDESKVPRCKYCG--GELTLCVDYFNPSPFAWDEV
SQQSRPTAVILELGVGLNTPGILRWPNEEEAGGYRLIRAGLGAAGVELEFAVGIMGDLSIILDGLI-------------
>tr|A0A0F0II56|A0A0F0II56_ASPPA Macro domain protein OS=Aspergillus parasiticus SU-1 GN=P875_00117157 PE=4 SV=1
------------------------------SKARSWLQEADYLIISAGAGLSAAIGL-DYTSTS-LFQKHRLYDVFGFNDW-DSPNQKWAYYFLHLNMVR
--TWPASKLYETLRELAARFDDRYFVRTSNADGRFVANGFEKVSTPQGQYRFLQCFACRPDFPSDPDETKIPACQYCG--GELTLCVDYFNSGPFAWDDV
ARN--RRAVILELGVGLNTPAVLRWPNEEENPGFRLIRAGIGASGADLELAVGIEGDLNLVVEALV-------------
>tr|J5SN00|J5SN00_TRIAS Uncharacterized protein OS=Trichosporon asahii var. asahii (strain ATCC 90039 / CBS 2479 / JCM 2466 / KCTC 7840 / NCYC 2677 / U
------------------------------VPDPSIFDNVGGLIIHAGAGLSADLGL-DYTSRD-LFYKLSLYETIGY-EW-DD---QWGWIFAHAHRVL
--NWGQTSVYSDLKRLVTL--VPYTIMTSNADQLFAQSGFERIFTPQGCYARFQCLACTPDFDSKPTPELIPSCEKCG--GAVFLNVDWFLETAYGYEEM
FRTQNKRVLVLELGSGFNTPSVIRYPSEME----DLVRVNLQHP-IQVG---GYKMGAGEFLAACV-------------
>tr|C4M8N0|C4M8N0_ENTHI Putative uncharacterized protein OS=Entamoeba histolytica GN=EHI_114350 PE=4 SV=1
------------------------------NRVIKFFKNATHIIIGAGAGLSVDAGL-SFMDTK-LFSEMSLYQTMGFEDF-KTENQKWGFFAVMADYMR
Y-KEVNFDTYKKLLDLLKY--KNYFVKTTNVDGLFERSGYNKFFNPQGDFKYIQCSTCSQDYLFKPD-SCIPKCPKCG--KEMTQNLEFFVEKPHVFEDA
IKN--GKVLFIEFGVGGNTPIHILIPFENI-ENTMLVRINLDKSFQVPT-YSAFHTTGKQFVEWLW-------------
>tr|L7FNL5|L7FNL5_ENTIV Uncharacterized protein OS=Entamoeba invadens IP1 GN=EIN_118830 PE=4 SV=1
------------------------------IKVVNFLKDATHVVIGAGAGFSVDAGI-DFMNTK-YFRSFKMLETIGFHDF-NEESQFWGFFAVTITEMR
Y-KPLTNRYYKQLLDTLQL--KKYFIKTTNVDGLFERSGFDKVFHIQGDMNQIQCSKCTDEYEFKPE-KYIPKCPRCG--GKMTFNLDLFVDGPNFYGEG
MND---KMILFEFGVGRGTPVHIRFPFEKN-KNVLLVRINMDKDLLVDD-YAGFGMSGKEFIEEMV-------------
>tr|A0A0F4YY72|A0A0F4YY72_TALEM Putative phosphatase-like protein OS=Rasamsonia emersonii CBS 393.64 GN=T310_3379 PE=4 SV=1
------------------------------VKARKWIQEADYLIISAGAGLSAAVGL-DYTSAD-LFRKHRLYDAFGFDAW-ESPQQEWGYHFTRLDLVR
--SWPPSTLYGRLLRLAERFGQRYFVRTSNADGQFVVNGFERVATPQGQYRYLQCLACRRDFPSDPDVTKIPHCPYCG--DELTVCVDYFNPAPFAYRQV
TQDARKKTVILELGVGLNTPGVLRWPNEDEEGRFRLIRAGIGAAGAELELAVGIAGDLNGVVAALV-------------
>tr|R1G891|R1G891_BOTPV Putative appr-1-p processing enzyme family protein OS=Botryosphaeria parva (strain UCR-NP2) GN=UCRNP2_8914 PE=4 SV=1
------------------------------ETARGWISQADFLLITAGAGLSAAAGL-DFTSQS-LFRKHRLYDTFGWDEW-PSKAHKWGFYFTQLQLAR
--TWPASPLYASLLDLAARFDGRFFVRTSNADGFFPANGFERFSSPQGAFKYLQCLRCRPDFRSKPDKSKIPVCEYCG--GDVFLCVDWFNERPFEYDQI
ERE-GKTAVVLELGVGMSTPGVLRWPNEQREGKVKLIRGGEQAAGVDLANAIGIEGNINDIVTGLR-------------
>tr|K2S238|K2S238_MACPH Appr-1-p processing OS=Macrophomina phaseolina (strain MS6) GN=MPH_06310 PE=4 SV=1
------------------------------QTAREWIYQAEYLLITAGAGLSAAAGF-DFTSQS-LFRKHRLYDTFGWDEW-PSKAHGWGFYFTQLQLAR
--TWPASSLYTSLLELASHFDGRFFVRTSNADGFFPNNGFERFSSPQGAFRYLQCMKCRPDFRSKPDDSKIPVCEFCG--GEVYLCVNWFNERPFEYDQV
ELE-GKTLTILELGVGMSTPGVIRWPNEEREGKIKLVRGGEQAAGIDLANAIGIEGHISDIVQGIR-------------
>tr|A0A0C1C401|A0A0C1C401_9EURO Uncharacterized protein OS=Aspergillus ustus GN=HK57_00419 PE=4 SV=1
------------------------------RKAQSWLRSADYLIISAGAGLSAATGL-DYTSPD-LFAKHRLYDVFGYDGW-DSPLQKWGYYFTHLNMVR
--TWPPSPLYASLRELAERFGRRCFIRTSNADDLFVANGFSRITTPQGQYAFLQCFDCRTEFASGPDSSMIPLCEFCG--GELTLCVDYFNSSPFAYEQV
SNDAGPKGVILELGVGMNTPSVLRWANDEEERGFRLIRAGLDAAGADMELAVGISGDINAVVDMLI-------------
>tr|C8VJV3|C8VJV3_EMENI Uncharacterized protein OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) GN=ANIA_11190 PE=4 
------------------------------KTARSWLEQADYLIISAGAGLSAATGL-DYTSTD-LFANYRLYDVFGFSGW-KSPAQKWGYYFHHLNMVK
--TWPKSPLYASLLEITSRFG-RCFVRTSNADGLFLANGFSRISTPQGQYAYLQCFACKREFPSAPDESKIPRCRYCS--GELTLCVDYFNDSPFGYEHV
SSEQGRSAVILELGVGMNTPSVLRWHNEEENGGSRLIRAGFDAAGVRLEVAVGVAGELNAVVDLLR-------------
>tr|U4LSX2|U4LSX2_PYROM Similar to Uncharacterized protein SAR0322 acc. no. Q6GJZ1 OS=Pyronema omphalodes (strain CBS 100304) GN=PCON_04258 PE=4 SV=1
------------------------------AKAAEMIRGADALLVTAGAGLSASYGL-DYTSQE-LFSTHCLYEIIGH-KF-ASAVDLWGYFFSHISTIC
--NWALTTVYDDLLALT-RFDDNYFVRTSNADGLFSRHGFERISTPQGDYRFIQCTACRPDFPSDASEEGVPLCPYCG--GDMFLCVGTFNDYPFEYNHV
KKE-GKKLVVLEIGSGWNTPGVIRWPNEAE--GATLVRIGMKGSEVGFGKAVGISGDAGWIVKELL-------------
>tr|A0A0D2UI13|A0A0D2UI13_CAPO3 Appr-1-p processing enzyme family protein OS=Capsaspora owczarzaki (strain ATCC 30864) GN=CAOG_005340 PE=4 SV=1
------------------------------SKATQWLRDADYVLIAGGAGLSAAAGL-DYNDRA-LFKRLCMYEFIGFTNW-TPELQ-WGYLLSQLDKAR
Y-NWPL--VYG---NLL-IAAEHHFVLTSNADGMFERNGFTRVYTAQGEYGRMQCLKCTQ-WPTRPNADVVPRCPNCG--GPVMMNVNWFIDQPYEFKST
---RDKRLVVIEVGAGFNTPMVVRYPCEDE-PQARFIRINTEHS-VSLN-SVSFDQDATTVLERLR-------------
>tr|M7TJU7|M7TJU7_EUTLA Putative appr-1-p processing enzyme family protein OS=Eutypa lata (strain UCR-EL1) GN=UCREL1_6003 PE=4 SV=1
------------------------------SRARNWLAMSSRLIISAGAGLSASTGL-DYTSSA-LFTKHSLYSVFGFDEW-PSDAARWSYNMHHLEVVR
--RWPRSKLYDDLLSFARRFKKKWFVKTSNADGFFAKHGFARICTPQGQYAFMQCATCREDWPSEPDDYEVPTCKFCG--ADLTLCVDYFIEAPFEYKEC
LAEDAVTTTILELGVGMNTPSVLRWHNEHQKGKFRLVRLGLDAAGVALELAVGLYGDIARLFEVLD-------------
>tr|A0A074YFS0|A0A074YFS0_AURPU A1pp-domain-containing protein OS=Aureobasidium pullulans EXF-150 GN=M438DRAFT_390698 PE=4 SV=1
------------------------------QAARTITREADYLIISAGAGLSASAGL-DYTSAD-LFSKHCLYDVFGFQSW-PSEQARWSYFMNHLIIVR
--DWQQQELYSNLWRTITRFGDRYFVRTSNADGLFVRHGLSRVSTPQGHYAQLQCIRCRKNFDAAPADFPVPVCPYCN--SDLVLCVSYFNDHPFQYERA
LESSANKVVILEIGVGMSTPSVLRWHNEDEEGQIKLVRVGRDAAGCELEVGVGVQGDISDILAAIM-------------
>tr|A0A010RTM6|A0A010RTM6_9PEZI Uncharacterized protein OS=Colletotrichum fioriniae PJ7 GN=CFIO01_03934 PE=4 SV=1
------------------------------DRARQWLDAADAVIVSAGAGLSASDGL-DYTSSA-LFAKNTLYSVFGFNSW-PTEQVRWGYYFTHLAMVK
--SWPESRMYRTLISWLKF--ENAHVRTSNADGLFVSNGLERLSTPQGSYSVFQCLGCRPEMPSAPEPSKVPLCKFCN--GKMNICVHWFNEKPFDWRDV
VHREERTTVILELGVGMSTPGVLRWPNEDMGGKVKLVRVGKGPETVDLALATSIDGEISAVVSELL-------------
>tr|A0A066XYK7|A0A066XYK7_COLSU Uncharacterized protein OS=Colletotrichum sublineola GN=CSUB01_07902 PE=4 SV=1
------------------------------DKARHWLRSVDTVIISAGAGLSASDGL-DYTSSD-LFAKHTLYSVFGFDGW-PTEQVRWGYYFTHLGMVR
--SWPRSKMYRTLIAWVKF--ANAHVRTSNADGLFVANGLGRLSTPQGSYSVFQCLQCRPEVFSAPDKSKVPFCRFCG--GKMNICVAWFNETPFDWRNV
LTDANKTTVILELGVGMSTPGVLRWPNENMKGRVKLVRVGLGPETVNLELATSIEGNISTVVMELL-------------
>tr|T0LY60|T0LY60_COLGC Uncharacterized protein OS=Colletotrichum gloeosporioides (strain Cg-14) GN=CGLO_03515 PE=4 SV=1
------------------------------DRARQWLTTADAVIVSAGAGLSASDGL-DYTSTA-LFAKHTLYSVFGFNGW-PTEQVRWGYYFTHLGMVS
--SWPKSPMYGTLISWLTF--ENAHVRTSNADGLFVANGLEKLSTPQGSYSVFQCLACRPEVLSGPDPSKVPLCKFCG--GKMNICVHWFNEKPFQWRNI
VHREDKTTVILELGVGMSTPGVLRWPNEDMGGKVKLVRVGMGPETVDLDLATSIDGDITTVVSELL-------------
>tr|N4V1W1|N4V1W1_COLOR Appr-1-p processing enzyme family protein OS=Colletotrichum orbiculare (strain 104-T / ATCC 96160 / CBS 514.97 / LARS 414 / MAF
------------------------------ERARQWLESADAVVVSAGAGLSASDGL-DYTSPA-LFAKHTLYSVFGFDRW-PDERVRWGYYFTHLGMVA
--SWPRSTTYGTLISWLRF--ESAHVRTSNADGLFIANGLERLSTPQGSYSVFQCLACRPEVPSAPDANKMPICRFCG--AKMMICVGWFNETPFEWDKV
MARRDKTTVILELGVGMSTPGVLRWPDEDVGGRVKLVRVGMGPEAVELDLATSIDGDISTVVRELF-------------
>tr|D8TL05|D8TL05_VOLCA Putative uncharacterized protein OS=Volvox carteri GN=VOLCADRAFT_116301 PE=4 SV=1
-------------------------------------------------------GMSMFSTRNGLYERFKVIKLFTYSFYRQRRAEVQAFFAQIYSEAQ
--ASRAATGHYAMAQLLQL-GALQRHYTLNIDGLSEVVGMDSTVEMHGNIRQLVCPTCHAVEPLSRHNQQPVPCSACGQ-DQLRFKVMLYDDDPEVFDVL
EEDLQVCDMVVWAGISFQQSASVEYFRRVRHNAVPQVLINPSEEPYFNPNELDLRETSDIAFPAMAERIREAI------
>tr|A0A0D2MLJ9|A0A0D2MLJ9_9CHLO Uncharacterized protein OS=Monoraphidium neglectum GN=MNEG_4212 PE=4 SV=1
--------------------------------------------------------MSMFSTKGGLYERFKIIKLFSYPFYKQRRVDVQAFFAQIYSEAQ
--SSRAAQGHHALAELWRM-GVLARHYTLNIDGLAEVVGMDVTVEMHGNIRDMVCPECHAVEVLSRPIRQPVPCTKCGQ-GEMRFKVMLYDDEPEVWESL
EADL-QADMVIWVGISFEQSASTEYFRKVRYDACRQVLVNPSDEALFNRRDLEVLAGADDVLTSLAERLGKLH------
>tr|G2YHT9|G2YHT9_BOTF4 Uncharacterized protein OS=Botryotinia fuckeliana (strain T4) GN=BofuT4_P015820.1 PE=4 SV=1
--------------------------------LRELVRSSKKIVVISVAGISASADFPTFADMQKSKTSFD-RSLYSPSMISFHPT----FRGMC-ERLH
SDLTESSHFHKVMDELGRT-RPHFWHYTQNIDCVERLLPDAKTIRLHGRVDQARCA-CKEARPER---------SLTI--GRLRPNVLLYGEPHPILEAA
KHGLRICPLVLIVGTKLRIPGAKSICHAARSDGA-SFWISKEEPALKSVCDYVLIKDCDEVIPL---------------
>tr|U5HC55|U5HC55_USTV1 Uncharacterized protein OS=Microbotryum violaceum (strain p1A1 Lamole) GN=MVLG_04743 PE=4 SV=1
------------------------------SDIATAMAQARNTIVMLGAGASTKAGITDFRSKGGWYSRQAPEASSSPSFFFRNPSTSLKFFASFKNQVD
QSSRGVTSLHRFLGELNVM-RKLGRVYSQNIDGFERSGGLSDTVQLHGTVQDARCSECDHE-E------------WCGA--WV----V--QE----WASG
EKRISSKSTVLVCGSSLRIDGFVKMAGAVRARGGMCVLVNRERVSWEEVFDYHVMADCDDFMDRIRTEW----------
>tr|A0A0K0FQB2|A0A0K0FQB2_9BILA Uncharacterized protein OS=Strongyloides venezuelensis PE=4 SV=1
------------------------------EEAIEIINKSKKIVVLNGYQTIANSKVPHWKVNRDLLRKNSYKDIFDIECYKRNPFPLHEYANSFE-H--
W-SYEISNSLNFIKLLSDS-GRLLRCYSENIDGMEYLAHVQQFCAVNGSIACSICRICRRHYPWNSPIANLKYCEWCS--AVVVPCISFEKDIKSKYCTL
EYDALNADLLLILGTSLDVSPFNLLPKLFP--LIPKIMITKSFNPNTFIPDFICLGDPDTII-----------------
>tr|A0A0N4Z381|A0A0N4Z381_PARTI Uncharacterized protein OS=Parastrongyloides trichosuri PE=4 SV=1
------------------------------EDVKDSINKAKRIVVLNGYQTIEKSKVPHWKTNKDVLKRHTYKDIFDMALYKSNPFPLHEFANAFE-H--
W-TYDISNSLRFIKSLSDN-NKLLRCYSENIDGMEYIANIELLVTVNGNIVCSKCFECKRHYPWDCPIANLKYCDICM--SVVIPCISFEKDIKSKYQSL
KYDVMHADLVLIIGTSLDVSPFNLIPQLFN--SVPKIMISKSFNVNTFVPDFTLLGDPDDIV-----------------
>tr|A0A0K0E1Z8|A0A0K0E1Z8_STRER Uncharacterized protein OS=Strongyloides stercoralis PE=4 SV=1
------------------------------EEVIEIIKKSNKIVVLNGYQTISNSKVPHWKVNRDLLRKNSYKDIFDIEYYKKNPFPLHEYANSFE-Y--
W-SYELSNSLKFIKSLSES-GKLLRCYSENIDGMEYLARIHQFCAVNGSIACFICKICGRHFPWNSPIANLKYCELCM--AVVVPCILFEKDIKSKYYTL
EHDSLQADLLLILGTSLDISPFNLIPKLFP--LVPKIMITKSFNVNTFIPDFTCLGDPDDIV-----------------
>tr|B5HLL9|B5HLL9_9ACTN Putative uncharacterized protein OS=Streptomyces sviceus ATCC 29083 GN=SSEG_08344 PE=4 SV=1
------------------------------------LGEADRVLITAGAGLSAAAGY-DYGDEDRFRELFPAHRLGLRSGVPLPPELWWGYWAVHIDDIR
F-SAEPNPLYQQLRSLVG--DKDHWVMTSNVDALFARSGFDRIFTPQGDYGRYQCTTCTPTFDSRPDTGPLPRCPNCG--GEVEINVRIGPEFVPAGRRL
QDWLGSADLILEFGAGFNTPGVIRWPGENLTRHARLVRVNPTHPEPDDLATLSVPAGAGHLLNA---------------
>tr|L8GYZ2|L8GYZ2_ACACA Phosphatase OS=Acanthamoeba castellanii str. Neff GN=ACA1_060580 PE=4 SV=1
------------------------------ALAVQFVRRADYLIISAGAGLSASVGL-DYTSEA-VFARYPAMHLCMYQFIPISEELKWGYLLTHAHRAR
F-TWGPTELYTQLLRLAEQTGGRYFVKTSNADGFFEQSGFSRVFTPQGDYGNMQCLSCNGKVVFPTDPSAMPRCPRCG--GPVFFNVRWFIESPYQGQAY
RRFVERTVVILEIGAGFNTPGVLRWPNERQHECVRLVRLNTDYPEVPEQRAVGLPLDAAVVVPLFL-------------
>tr|S9PF99|S9PF99_9DELT NAD-dependent protein deacetylase of SIR2 family OS=Cystobacter fuscus DSM 2262 GN=D187_010340 PE=4 SV=1
------------------------------ELARRWLAESERVLIGAGAGMSAAAGI-DYGDTA-TFARFPAFVLAQYQFIGLTPAQHWGFWSTHVKHVR
F-GEDERPAYQTLRHLVK--DKDTFVLTSNVDMLFPRNGFARLFTPQGDYARMQCRK----ETWPTDPDALPRCPRCG--GDVFMNVRSFLEEPYVARRF
RQWMRRRLLVIEVGAGFNTPSVVRWRMEHHHPDARLIRINLTDPELPER-AVSLAMGASQAFELLG-------------
>tr|F6CE41|F6CE41_LACKZ Sir2 silent information regulator family NAD-dependent deacetylase OS=Lactobacillus kefiranofaciens (strain ZW3) GN=WANG_0645 P
-----------------------------AQLAHNWIKDADAILVTASNGLSISEGLNLFTNDGVLVDKYPIQNLLSAFSFPKNKLDHWRAIARIVEYYG
-NNYETSNYMSDIKDLID--NKPYFIWTSNVDHHFSLAGFKNVFEIEGNWFEGVCSEHPEKFQLGNTEADIPTCDKCG--SELDLNMA--GDNFKQVTKL
QNFLNKKLVVLELGIGPRN-QMIKMPTMQADPNAHYITINQGQLMIPNDRSIGFDSSLASTFKEILS------------
>tr|J7LKI8|J7LKI8_LACHE Sir2 silent information regulator family NAD-dependent deacetylase OS=Lactobacillus helveticus R0052 GN=R0052_00260 PE=4 SV=1
-----------------------------AQIAKKWIDESDAILVTASNGLSISEGLNLFADDGNLVDKYHLSNLLTAFSYQPDELDYWRVIARTVGYYS
-NNYQPSVYMQDLKKIIG--DKLYFAWTSNVDHHFALAGFDNLFEIEGNWLDGVCSAHPKKVNLAKTKADIPTCDKCG--APMNINTTA-NQDFKQINAF
QDFIDKKLVVLELGIGPRN-QMIKVPSMQVDRNSRYITINKGELNILDDRSIGFSASIGDAFKETMT------------
>tr|G5JNY5|G5JNY5_STRCG Uncharacterized protein OS=Streptococcus criceti HS-6 GN=STRCR_1516 PE=4 SV=1
-----------------------------LELAKKWIKDSDALLITASNGFAISEGLNLFTDNKGTFDRYHFQNLLSAFAYPDSPLERWSVLAPVINYFS
-YGYQDSAVMKQLKALIA--DKDYYIWTSNTDHHFVQAGLKNVFEIEGNWLEGICSNGHS-QDLSIQDRDLPVCQVCG--ESLELNLP--GDHFKKLTEI
QDFIGKSLLVIELGIGASN-QLIKAPSMESHPNHRYITINKGEVYIAPDQAIGIDGLLITALEELLT------------
>tr|A0A0R1P8G8|A0A0R1P8G8_9LACO Sir2 silent information regulator family NAD-dependent deacetylase OS=Lactobacillus frumenti DSM 13145 GN=FD27_GL000004 PE=4 SV
-----------------------------IKTAQQWLSDADAILVTASNGFSISEGLNLFAHDGDLVEKYNLPNLLGALNYHPDELDKWRVYARIAEYYN
-YNYYPGELMGKLRQIIG--DKPYFIWTSNVDHHFALAEFSNLLEIEGNWQTGICSNHPKDVDLKETEEDLPTCAECK--APLSLNIP--GSAFKQVSGF
ENFLDRKILVLELGIGPQN-QMIKAPSMQGNERSHYITINKGQLNIPSDRSIGFSSTIVDAFDALIT------------
>tr|A0A0R1L3S3|A0A0R1L3S3_9LACO Sir2 silent information regulator family NAD-dependent deacetylase OS=Lactobacillus futsaii JCM 17355 GN=FC88_GL001896 PE=4 SV=
-----------------------------IKIAKKWMNEADAVLITASNGFSISEGLNLFANDGELQDKYHFQNLLSVFGFKPNELEQWRAYARIIEFYS
-INYESSDLMQNLKRMID--KRPYFVWTSNVDHHFDLAGLENNLEVEGNWLEGVCSQD-KDVDLKNTESDIPKCSECG--SSLKLNLP--GDFFKKVTKF
SDFLDKNLLVLELGIGPRN-EMIKAPSMQGNGKSHFITINKGELYIPDERSIGFSTSIDTAFQELLT------------
>tr|A0A0R1YDE6|A0A0R1YDE6_9LACO Sir2 silent information regulator family NAD-dependent deacetylase OS=Lactobacillus hamsteri DSM 5661 = JCM 6256 GN=FC39_GL0004
-----------------------------VKLAHEWLENADAILVTASNGFSISEGYNLFANDGDIVEKYHLPNLIMAGNFQPSPVEHWRVLARIGEYYF
-NNYEESPYMSDLKEIIG--NKPYFIWTSNTEHHFDLAGLHNTLEVEGNSLEAVCSKHPDEFPLSSTEDDLPVCDKCG--APLEPNII--GDDFERLNKF
QEFIDKNLLVLELGIGPRN-QMIKAPSMQADKNSHYITINKGELLIPDDRSIGFSSSIGLAFKELLT------------
>tr|C2EN97|C2EN97_9LACO Sir2 silent information regulator family NAD-dependent deacetylase OS=Lactobacillus ultunensis DSM 16047 GN=FC57_GL000187 PE=4 
-----------------------------ASTAKEWIDNADAILVTASNGFSISEGLNLFANDGDLVDKYHLPNILTALSFDPNALDKWRAYARIIEYYG
-NNYEKTNYMQDLKKIIA--DKSYYIWTSNIDHHFELAGLNNTFEIEGNWFEAICSKNPKKFRLGETEDDIPKCDQCG--APLSLNLP--GDNFQKLAGF
QSFINKKLLVLELGIGPQN-QMIKAPSMQSSPNIHYITINKGQLFIPDDRSIGYSASIGTAFKELLT------------
>tr|A0A0D2YBF5|A0A0D2YBF5_FUSO4 Uncharacterized protein OS=Fusarium oxysporum f. sp. lycopersici (strain 4287 / CBS 123668 / FGSC 9935 / NRRL 34936) GN=FOXG_13
----------------------------SLSLAREWLSSADAVLVTAGAGLSAAEGL-DYHSRE-LFKRFGLTSLYSVFGFNDWEEHRWGYFFTHLNMVA
--NWSNTPTYQTLIPWLRNFGQDAFVRTSNADGLFLANGWERLSTPQGSYGYLQCLNCRVVVSSAPDSSKIPLCRFCG--SKMSICVSWFNQVPYQWKAW
KSRVKKNLVILELGVGMNTPGVLRWPNEDLDGRVKLIRVGMGPEAWEEGLSTCIQGDIGRAIPLLL-------------
>tr|A0A0G2IDB1|A0A0G2IDB1_9PEZI Putative appr-1-p processing enzyme family protein OS=Diaporthe ampelina GN=UCDDA912_g02396 PE=4 SV=1
----------------------------SLEAARTWLDSADAVLISAGAGLSASDGL-DYTSPA-LFARYGLRTLYGVFGFAEWEQVRWGYFFTHLAMVR
--AWPASHVYHTLISWLGRFDKGAHVRTSNADGLFLANGLDRLSLPQGAYAVLQCLACRPTVPSAPDPGKVPVCQFCG--GRMNICVSWFNEVPFRWKQF
RRDVEKTTVILELGAGMSTPGVLRWPNEDLRGRVKLIRVGLGPETWGAGLAISIDGDISAVVRELL-------------
>tr|A0A0N0V558|A0A0N0V558_9HYPO Phosphatase OS=Fusarium langsethiae GN=FLAG1_10079 PE=4 SV=1
-----------------------------LRIARDWLRSADAVLVTAGAGLSAAEGL-DYHSRD-LFKKFGLTSVFGYNGW-PSEEYRWGYFFTHLNMIS
--NWSNTPTYQALIPWLREFGPDAFVRTSNADGLFLANGWKQLSTPQGSYAYLQCLNCRADVPSADDSTKIPVCRFCG--SKMSICVSWFNQSPYDWKAW
KAKEKKKLVILELGVGMNTPGVLRWPNEDLSHGVQLIRVGMGPEAWDSGLSTFIQGDIQRVVPLLLDNV----------
>tr|K1WUR3|K1WUR3_TRIAC Uncharacterized protein OS=Trichosporon asahii var. asahii (strain CBS 8904) GN=A1Q2_01102 PE=4 SV=1
-----------------------------------IFDNVGGLIIHAGAGLSADAGL-DYTSRDLFYKLYPLRSLYETIGYE--WDDQWGWIVAHAHRV-
-LNWGQTSVYSDLKRLVSTLDVPYTIMTSNADQLFAQSGFERIFTPQGCYARFQCLACTPDFPWIEKPELIPSCEKCG--GAVFLNVRWFLETAYRYERT
AEAQNKRVLVLELGSGFNTPSVIRYPSEMLAERADLVRVNLQHPEIHSQEGRGYKMGAGEFLAAWQD------------
>tr|A0A066VCU2|A0A066VCU2_9HOMO Uncharacterized protein (Fragment) OS=Rhizoctonia solani AG-8 WAC10335 GN=RSAG8_09719 PE=4 SV=1
------------------------------AAIINTIAKTEKILLMSGPGISVACGLPHLDMDNGGSNYETLQNALNAQAKS-VPEDFNKYMADLRIRA-
-RSAPMSAFHLLLRRALRE-KRVMRCLTTNFDGLDEQPDPEKVIRMYGDNRFLRCCMCPGMCSAEDRLDGVVYCPPCTQMRLLRPAVDILPELHRLRTKV
IQDAKSCQLLLIVGLPLKSGEVYDLMRELAQRYGAVIYVDNQPIRGRGSIDFHLHVGIEEFATRVLAAM----------
>tr|X8IWN7|X8IWN7_9HOMO SIR2 family transcriptional regulator (Fragment) OS=Rhizoctonia solani AG-3 Rhs1AP GN=RSOL_032800 PE=4 SV=1
------------------------------NAVLEAIAKTEKIMILSGSEVSVASGMPALTQTNAFSSQMPLRAMQDRDLFQ-LAEDYNKVMAARRIQA-
-RSAPANAFDQYFHQVLQK-KHVVKYLTTSFDGLEANKKRGKIVRMHGDNRFLRCSTCPGMTEKDELSGATLLCAHCSESYSLRPAVQSLGDMLPIRNKV
VTAAKGADLLIIAGISLQSDEIMELVREISARYGGVVYIGSQPIRGRYYVDFHLKMDVDECAKQILGVM----------
>tr|A0A0B7G6A7|A0A0B7G6A7_THACB Uncharacterized protein OS=Thanatephorus cucumeris (strain AG1-IB / isolate 7/3/14) GN=RSOLAG1IB_11022 PE=4 SV=1
------------------------------NAVVEAIAKTDRIIFLCGPDLSTAAGMAALNKPNGIASQMSLSALPDRGLSQ-LPNKYNMAMAERRIRA-
-RSAPINTFHQYFQRVFGL-KHVVRYLTTSFDALEAAGKRSKVIRMHGDNRILRCCTCPGVREKDGLRGATLLCEDCPLSNHLRPAVQAIGDMLPLRNKV
ITGAKSTDLLLIAGISLQADEIMDLAQEIAGRYGGVVYIGEQPICGRYHVDFHLKMDPDECAHHIFDAM----------
>tr|R9JCV2|R9JCV2_9FIRM Uncharacterized protein OS=Lachnospiraceae bacterium 28-4 GN=C807_00790 PE=4 SV=1
-----------------------------KDILLEKIEDAELVLVGIGEEFEES-----VPKVEPEFSD-----ALR--RMEEQEKDAWPYFKKAYLDR-
SKGDKTKEAYSILDNLLE--GKNYFIVSTRTDDYIYKTKLERIVTPCGGYRFCRCAECNKQYPADGDKIEQPVCPACG--KNLVFNLVGYIEELPQWNQY
MKWLNKKLCVLELGVGMKYPTVIRWPFEKINQKANIFRVHSKLYQLTKDRGYKIEKKPMDFLIN---------------
>tr|R6BX02|R6BX02_9CLOT Uncharacterized protein OS=Clostridium sp. CAG:510 GN=BN687_00034 PE=4 SV=1
-----------------------------LMEIKEKIQAADMVLVGIGEEFEDEAF-LQEK---ENYAE-----ICG--K-IAEAGAQWPYVNYLFLKE-
--DTRLKKAYEGLTSLLQ--GKNYFILSYCMDGLLSEQELDRMAEFCGNWRHFTGEPENEKALYR-ADLKAPVSLKTC--QPCEFNTLYFEEPKENWDRY
LKWLNKKLCILELGAGMRNLNTIRIRYEKINLKSDFIRIHEYLYQIPAERGTGIQKNAVYAMEE---------------
>tr|U2AZL0|U2AZL0_9CLOT Uncharacterized protein OS=Clostridium sp. KLE 1755 GN=HMPREF1548_01574 PE=4 SV=1
-----------------------------TKELLAEIADAQMVLVGIGKEMEET-----YKKMESFYSS-----LMA--QAEKEEDAAAQYLQCYYREK-
NPDSGKIDAYNRLADLLE--GKNYFVVSLCTDDYIYSSKLGRIVTPCGGFRALQCHSCSTDEPLVWEKVDFPVCAECC--SIMYFNRIDYKEELPQWEKY
TKWLNRKLCILELGAGMEYPTVIRFPFEKVNQKARFYRVHSRLYQMTKEKGVSIQANPEEFLKN---------------
>tr|R9MVJ0|R9MVJ0_9FIRM Uncharacterized protein OS=Lachnospiraceae bacterium 10-1 GN=C819_02493 PE=4 SV=1
-----------------------------KKRIVAKIDEADMVLVGIGEELDQI-----IKANKTYI------------KLREKTESTWPFMKSILVEE-
QI-EESKKIYHNLFHILD--KKNYFVVSTCQDCLVRYGGFERIVEPCGGYSMLQCSDCSTEYSVSEADLEPPRCPYCG--KFLVFNNIDYNEELRKWMIY
KKWLNKNLCILELGVGMNYPSVIRWPFEKINQKSELFRVHSRLYQITKDRGYGICQKPEDFIRE---------------
>tr|F7KLL0|F7KLL0_9FIRM Uncharacterized protein OS=Lachnospiraceae bacterium 3_1_57FAA_CT1 GN=HMPREF0994_06748 PE=4 SV=1
-----------------------------TNELLQDIADSQMVLVGIGKEMEEN-----YQGMNTFYGP-----LLA--QAEEEKDRAAQYLRCHYVRR-
HPNPRIKKAYEKLTALLD--GKNYFILSLSEDDYIFNSGLERIVTPCGGFRELQCTECNAEESLVTESVDFPVCTDCC--GILWFNRIEYREELTQWEKY
TKWLNHKLCILELGAGMEYPSVIRFPFEKVNQKSVFYRVHGKLPYLTSERGISAKTDAITFLSE---------------
>tr|R9JSF2|R9JSF2_9FIRM Uncharacterized protein OS=Lachnospiraceae bacterium A4 GN=C804_00093 PE=4 SV=1
-----------------------------QTILVEKITDADMVLVGIGEEFHED-----FKEIHPNLMS-----ALE--EVDINETLEWPFLEHRFLIE-
HKDGSLEEAYKKLYELVK--DKNYFVITTCIDEIIQRAPFERVVAPCGNYQMLQCSECCNTYPSKDASLEEPKCPVCG--KSLVYSNILYVEEQKQWENY
TKWLNKKLCILELGVELNLPNIIRWPFEKVNQKASFFRINASLYQMTSGKGVSIAMNAVDFLRE---------------
>tr|E0S2L0|E0S2L0_BUTPB Uncharacterized protein OS=Butyrivibrio proteoclasticus (strain ATCC 51982 / DSM 14932 / B316) GN=bpr_I1238 PE=4 SV=1
-----------------------------EQRLSELIEKADQCIIGIGSEWNWV-----KSGINCRYSQ-----ILE--Y-CKQEGNQWPIVEYEFAYY-
NNDNRIEEAYKGLRKLIG--DKKYFLVSDLFLQDALLYGFSKVVYPCGNYMYLQSTNKDPLEAQKVES-VFSKPFSEG--KELYLNQKRYNESKGRWDEY
MQYLNSNLLIIELGVGLEHPTVVRWPFEKVNKKAHFVRVHEKLYHHTGDKTDSIQMNSVDFILQ---------------
>tr|R9KGS3|R9KGS3_9FIRM Uncharacterized protein OS=Lachnospiraceae bacterium COE1 GN=C809_02856 PE=4 SV=1
-----------------------------QRLLLEKLSQAQVVLVGIGEEFNEG-----FEDIGPELMS-----ALE--EVDTNPTLEWPFLEKCYLTQ-
HNEGRIIDAYAALYELIK--HKDYFIVTTCIDGNIGKVDFERIVEPCGSYAALQCSKCNDTVLPEAASLERPVCRFCD--APLAFNNILYVEAKSQWEKY
TDWLHKELCVLELGVGMSLPGIIRWPFEKANKRASFFRINEQLYHITENKGISIAMHAADFLNG---------------
>tr|R7R8T1|R7R8T1_9FIRM Uncharacterized protein OS=Roseburia sp. CAG:100 GN=BN450_02664 PE=4 SV=1
-----------------------------TEILKEKLADAEVVLIGIGEEFNEK-----FDRIAEQLVK-----GLE--LVDAKEELAWPYFEKIYLQE-
QNQSDILSAYRNLYELVK--DKNYYIVTTCIDGLIQKAGFEKIVEPCGNYEKMQCSACSTRYESEEAQVEQSVCPDCG--APLAFNNIVYVEELPQWQKY
TKWLNHRLCILELGVGMNLPNVIRWPFEKVNQKASFFRINESLYQIAGDKGIGIEENACDFLMK---------------
>tr|R6RLE0|R6RLE0_9FIRM Uncharacterized protein OS=Anaerostipes sp. CAG:276 GN=BN583_00665 PE=4 SV=1
-----------------------------LKDYVSRIQDADLVLVGIGPELSAYEL-IDFKTEIEHYQK-----LLR--MDEEDKDVIWQAYERHYLLN-
HS---QVSYFKKLEEVLD--QKDYFVITSNNDGLIFHSGLNRLTAPCGSGDFFQCKGCSEQYPADLDKIEHLECPKCG--APLVYNIRTYIEGLNSWAAY
TKWLNKKLFILELGEGFGVPGLFRWPFEKMNEKAYMVRVNRTLYQIGKGKADAVKMDSKDFLEI---------------
>tr|B0NWI6|B0NWI6_9CLOT Uncharacterized protein OS=Clostridium sp. SS2/1 GN=CLOSS21_00079 PE=4 SV=1
-----------------------------LKDYKEQIQDADLVLVGIGRELRADRV-IDFKKAIEHYQN-----LID--K--EDEDSKWTVYEREYLLS-
MK---ETDLFKELEEVLE--GKEYFVVTSNDDGLLYHTHLDHVTAPCGNGDFFQCSACDEQYPANLDKIEHLECPKCG--KQLIFNVRTYIEGLNSWASY
TKWLNKKLFILELGEGFEVPSLFRWPFEKMNEKATFVRVHHSLYQIGKEKGIGIKMDSRDFLNI---------------
>tr|A0A0K6G9A4|A0A0K6G9A4_9HOMO Eukaryotic translation initiation factor 3 subunit B OS=Rhizoctonia solani GN=RSOLAG22IIIB_05768 PE=4 SV=1
------------------------------ATVIETIAKTEKIMLMSGPGVSIACGLSYLDEQDSQYGS-SLQNACSLLAKSVSEDKLAAFMVDLRIRA-
-RSAPMSIFHLLLQRTLRE-KRVMRCLTTSFDGLDQQPDIEKVIRMYGDNRFLRCCMCPGIYSAEEDSKGIVFCPPCTRMRLLRPAVDIHPTLQGLRSEV
MKEAKSCQLLLIVGLPLKSGEVYDLMRELHHSYGAVVYVDNETIRGRGIIDFHLQMDIEDFSSRILVEMDNHRE-----
>tr|A0A066V2D3|A0A066V2D3_9HOMO Uncharacterized protein (Fragment) OS=Rhizoctonia solani AG-8 WAC10335 GN=RSAG8_11426 PE=4 SV=1
------------------------------SEVLATIGRTQKMMVLSGENVGLAAGLLPVSAPGQGQTN-TLRGLCSPTPDQLP-ERLALNMTRRRIAA-
-RSAELTKFHHLLGRLFDE-GRLISYLTESFDGIEERSSFDRVVMLYGDNRLLRCCMCRMTLEDAAT-----------LTRALRPAVQGSGAMLEDRQAM
KGAAGKCQLLLILGISLKDPEILDLTRELRSNYGGVVYVSPQALRGGDHIDFHLKVEPEVAIDGISSALDKAND-----
>tr|M5CEG6|M5CEG6_THACB Uncharacterized protein OS=Thanatephorus cucumeris (strain AG1-IB / isolate 7/3/14) GN=BN14_08419 PE=4 SV=1
------------------------------ADIVAGIARTKKILVMSGDGAHLLSGLLPLESPGDFRRK-PLRTVATRGELSS--NELCMYMVERRVAA-
-RKATPGKMIDFLKRLCDD-GRLSKCLTTSIDGFECQSSVDLVIPLYGDNRLLRCATCRVLSEEDSEGDEPASCRRCTLSRWLRPAVQLYGLFVHDSALI
TQFHGGSKLLLIVGTQPKDPELLNLTRELHDADGAVIYIDPSPLHGTDHIDIQLQSDVDVVLGDVLSAMDREPI-----
>tr|A0A0K6G3K6|A0A0K6G3K6_9HOMO Alpha-mannosidase OS=Rhizoctonia solani GN=RSOLAG22IIIB_10430 PE=4 SV=1
------------------------------NEVLTTIGRTQKMMVLCGEDVCLAEGLLVACEL---------------TAERRTLQHLWIIFTKNNSCG-
-KSPVGQAGGAELCRLFDE-GRLVRYLTESFDGVEERCWFDRVTMLYGDNRQLCCCTCRKTSVSEADEGVTVICPDCNRTRALRPTVQLAGAILPEREAL
KAAAETCQLLLIIGTSLKDVDILDLTRELHSKYGAVVYVNSRSLRGGDHIDFHLLAEPEVVVDGILFALDEANN-----
>tr|X8IZS3|X8IZS3_9HOMO Uncharacterized protein (Fragment) OS=Rhizoctonia solani AG-3 Rhs1AP GN=RSOL_052980 PE=4 SV=1
------------------------------SEVLATIARTQKMMILCGENVCLAEGLLPVGAPGQGVPN-TLRGLCSPTAEQLP-DKLALNMTRRRIAA-
-RSAPLTTFHDLLGQLFDQ-DRLVSCVTGSFDGVEERCRFDRLVMLYGDNRQLRCY-----------------------TRALRPTVQFSGAMLEDRQEM
KKTAEACQLLLIIGLSLKDTDILDLTRELRSKYGGVVYVNPLPLRGGDHIDFHLKVEPGVVVDGILSFLGEPNS-----