>seq_1
MRVPEKYSTLPAEDRSVHIVNICAIEDLGYLPSEGTLLNSLSVDPDAECKYGLYFRDGKRKVDYILVYHHKRASGSRTLARRGLQNDMVLGTRSVRQDQP
LPGKGSPVDAGSPEVPMDYHEDDKRFRREEYEGNLLEAGLELENDEDTKIHGVGFVKIHAPWHVLCREAEFLKLKMPTKKVYHISETRGLLKTINSVLQK
ITDPIQPKVAEHRPQTTKRLSYPFSREKQHLFDLTDRDSFFDSKTRSTIVYEILKRTTCTKAKYSMGITSLLANGVYSAAYPLHDGDYEGDNVEFNDRKL
LYEEWASYGVFYKYQPIDLVRKYFGEKVGLYFAWLGAYTQMLIPASIVGVIVFLYGCATVDENIPSMEMCDQRYNITMCPLCDKTCSYWKMSSACATARA
SHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLRKESRNKETDKVKLTWRDRFPAYFTNLVSIIFM
IAVTFAIVLGVIIYRISTAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLTFKAFLLKFVNSYTPIFYVA
FFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKFIRYLKLRRQSPSDREEYVKRKQRYEVDFNLEPFAGLT
PEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAIRAKDIGIWYNILRGVGKLAVIINAFVISFTSDFIPRLVYLYMYSQNGT
MHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSEHKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKE
KVLMVELFMREEQGKQQLLDTWMEKEKPRDVPCNNHSPTTHPEAGDGSPVPSYEYHGDAL
>tr|H2V5J0|H2V5J0_TAKRU Anoctamin OS=Takifugu rubripes GN=ANO1 PE=3 SV=1
----------------------------------------QTPEEQIHCQQGLYFEDGQRRVDYVLTYHVKKPTGGRSSRQS------------------
-NL-L-----------TE--NDHKTFQREEFEKQLVDMGLELEKEED-KVQGVGFLKIHAPWKVLCREAELMKLKMPTKKVYEVKQSGSVTEKISSLVSK
ILEPLHPQVEERQPKNIKHLSHTFSREKHHLFDLSDKESFFDSKTRSSIVFEILKRTKSK-ANYNV-ITSLLGSGVYMAAYPLHDGDINEE-TESNDRKL
LYEEWANYSVFFKYQPIGLVRKYFGEKIALYFAWLGLYTQMLIPASLVGVIVFLYGCATVDDNIPSMEICHPENNITMCPLCDQVCSYWKLSTACGTARA
SHLFDNPATVFFSIFMALWAAMFMEHWKRRQMRLNYEWDLTGFEDEEEALKDHPRAEYEFQVLQKSFRKHQHLM-TGMEKLTYQDRLPAYMTNVVMMLLM
IGVTFATVFGVIFYRISTKAALHMSSNPVTRSHVQLTVKTTAAIINLVVILILDEVYGAVARWLTVLEVPKTDKSFEERLIFKTFILKFVNAFSPIIYIA
FFRG-FVGRPGSYLYVSESYRMEECAYGGCLMELCIQLSITMLGKQLIQNNLFEIGIPKLKKLLRYIQSKQGAV-PEEERQKKLQRYETDHFLEPFAGLT
PEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVGARAKDIGIWYNILRGVAKVAVIINAFVISFTSDFIPRMVYQYKYSQEGS
MHGFVNHTLSFFNVSHFQEGSEPLDQLHLGYPVEICRYKDYREPPWSNTPYELSKEFWTVLAVRLSFVIVFQNVVMLMSDIVDWLIPDIPKDISVQIHKE
KILLVDLFMKEEQGKVRNLES---------------------------------------
>tr|H3CGQ0|H3CGQ0_TETNG Anoctamin OS=Tetraodon nigroviridis GN=ANO1 (2 of 2) PE=3 SV=1
----------------------------------------QTPEEQSPCQRGLYFEDGERRVDYVLTYHVKKPSGGRSGRQA------------------
-SL-L-----------TE--NDQKTFRREEFERQLVDMGLELEKDED-KTQGVGFLKIHAPWNVLCREAELMKLKMPTKKVYEVKQSGSVTQKISSLVSK
ILEPLHPHVEEHQPKNIKHLSHTFSREKQHLFDLSDKESFFDSKTRSSIVFEILKRTKSK-AKYNV-ITSLLGSGVYMAAYPLHDGDINEE-VESNDRKL
LYEEWANYSVFFKYQPVGLVRKYFGEKIALYFAWLGLYTQMLIPASLVGVIVFLYGCATVDDNIPSMEICHPENNITMCPLCDRVCSYWKLSSACGTARA
SHLFDNPATVFFSIFMALWAAMFMEHWKRRQMRLNYEWDLTGFEDEEEALKDHPRAEYEFQVLQKSLRKHQIVA-SHMEKLTYQDRLPAYMTNVVMMLLM
IGVTFAIVFGVIFYRISTKAALHMSSNPITRSHVQLTVKTTAAIINLVVILILDEVYGAVARWLTVLGE-----TPVLAGTPVP-VRTQVPERTPVLTGT
PVPE-LTLLPAGLWSSWSSTPLVHMIWLGCWMFLH---DLSLQGANIIQL-------------TRWDNETKAN----AN---RRGSGRVRNARPPLADLA
KSVARPVIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAARAKDIGIWYNILRGVAKVAVIINAFVISFTSDFIPRMVYQYKYSPDGS
MHGFVNHTLSFFNISCFQEGREPLDQLHLGYPVDICRFTPS----YLGDTIEYSSFEFKHNCSPGADLFRYDNVVMLMSDVVDWLIPDIPKDISVQIH-E
KILLVELFMKEEQGK---------------------------------------------
>tr|T2MBD3|T2MBD3_HYDVU Anoctamin OS=Hydra vulgaris GN=ANO7 PE=2 SV=1
----------------------------------------EIYDEDMSGERGTYFRDGKRKIDFVLVYVEEKNQM-------------------------
---------------------TRLVGFRKRFLSNLKRSSVEMEEERCN-ENILHFIKCHCPFEVLKYYAEELSFKAPLARQ-------------------
---KF-----RLP--PPDYFTATFQADKFHLFLGENPSTYFTDTERTRI-YEILERAP---------IERLVAEGVFAAAYPLHVPREEGPEPQLNQRQV
LKMYWGRWGKWLKYQPLDLIRSYFGEKIGLYFAWLGQYTAWLLLPSVVGLLVFVYGCVTVNDNRDALDICEHAWTYKMCPLC-IGCKYWDLKTSCTRAKL
SYLFDNAATVFFAVFVSFWA-FFLEFWKRKEITLAYRWDCLDYESEV----EQPRPTYAALAPT-------RNPEPS------KQRVPRIYSGILIVITM
VSLVLI-MLG-IVYKLLVYRP---L-RNETA--ALQIANITGAVCNLICIMILSRVYEKVALALTHWEMHRTQTEYEDNLTFK---FQFVNFYASIFYIA
FIKG--TGYPGNYT------RMEE-GPGGCLVELAQQLVIIMVGKQMI-GNVQEVMIPLIKQKWKKRKRGK-------KTIELKPRWEDDYELVEN-GLF
AEYLEMVIQFGFITIFVAAFPLAPFFALANNIFEIRIDSNKLICETRRPIADRAQDLGIWYDILDAVAKIAVISNAFLIAFTSNFLPKLLYRSSISP---
LEGYLNYSLAVS-----PHNTTL----------QPCRYRDFRDEEGR-----LTAFYWHLLAMKLGFVIVFEHFVFATHKFIDFLVPDIPEELDIAIKKE
AYQAKKAMSDHPNLIIANSEEEL-------------------------------------
>tr|A0A074ZBW2|A0A074ZBW2_9TREM Anoctamin OS=Opisthorchis viverrini GN=T265_07620 PE=3 SV=1
----------------------------------------VHNNEPTRKIQGYYFADGKRKIDYVLVWEDNPDEKHPSK---------------------
---------------------RTNRRLRNEYLANLHKIGVETELEVVP-TTQTYYLKLHIPWTLMCDYAEMLHLRAPLEVG-------------------
---AL-----HIP--PTEYYTCQFKKSKIEKFLGNVPDSYFNSTQRHQV-YEILASQP---------IDRLIEENVYSAAYVLHETEEDL-PEQMNPRQI
LYWYWARWGCWYRYQPVNHIRQYYGEKIGFYFAWLGLYTAWLLPAAIVGIMVFLYGLFTMNNYTPSNEACDSD--NVMCPIC-QGCRYWHLKDMCFYLRV
SYLFDHPGTVFYAIFMVIWG-TFLEYWKRKNAKLAHRWDVLDYELEE----ERPRPQYSALCSE-------KNLEPR------TRRILRLIAGLLCVLWM
IVLVMV-IVA-IIYRLLIMVP---L-KNKLR--AGIYASMSGALVNLVVIMCLGKVYEKLAQKMTEWEMHRTQSEFDNQLIFK---FQFINFYSSIVYIA
FFKG--VGYPGHYT------RNED-NNGGCLIELAQQLLVIMVGKQLI-NNCQEILIPKIRGWWHKKSKGLNK----NSTITSDCVYLDDYKLIPY-GLF
DEYLEMVLQFGFITIFVAAFPLAPFFALLNNWIEIRLDANKLVCETQRPLAERAQNIGVWFRILDILVRLAVISNAFIIAFTSNFLPKLLYKYEI-----
LVGFTNFTLAWA-----PNNTTK----------LPCQYTAFRDPQGE-----YTMFYWRLLALRLIFVIVFEHVAFLLADLFDFLIPDVPSSLEERIQRE
RFLAKQALLDVHLETSKTSEKFD-------------------------------------
>tr|W5MKX8|W5MKX8_LEPOC Anoctamin OS=Lepisosteus oculatus PE=3 SV=1
----------------------------------------ERPRLQSPHPRGNYFKDGKTKIDFVLVWEVKTLSQRKRRARGR-----------------
-Y-------------------AQHQRWRDKFVRNLQSSGLLLET----ERKTIHYLKLSAPWEVLVYYAEELCLRAPLQ---------------------
---KL-----CVP--PVDYYTCAFRRSKMSRFLGEDRDSYFSSTQRHRI-AEVLARTA---------MERLLSEGAYTAAFPLHEFKT----SELNLAEC
CS-PRPSSCTYSSYSSSCVGQWSLPQCCALFPPAAGFYTAWLLPAAAAGTLVFISGIVTMGTNTPAEEICSSRGRYLMCPLC--TCSTWNISDICSMAKL
GYLFDHPGTVVFSVFMSLWA-TFLEYWKRKSATLAHHWDCTDFREVE----ERPRPEFAATAPK-------QNKEPE------KDRISRILTGSMVIIIM
LCVVMI-LVT-IMYRGIVSMMMYHT--SALR--AGNIANISGSMVNLALILLMGQLYTALAQQLTKWEMHRTQTQHEDAFTFK---FQFVNFYSSPFYVA
FFKG--VGYPGHYG------RNED-GPGGCLIELAEQLFIIMVGKQII-SNIQEFLIPKVKSWLQKRELAALRG----I-PQEPKRWEEDYELLQC-GLF
EEYLEMVLQFGFITIFVAAFPLAPLFALLNNWVEIRLDAQKFVCEYRRPVAERAQSIGVWFHILEALSQLSVIVNAFLIAFTSDFLPRLLYQYRFD----
LHGYVNFTLAEA-----PASYTHAN-------HTGCRYKAFRDSDGS-----YTLFYWELLAVRLGFIIVFEHVVFFVLRVIDGVVPDVPESLELQVRRE
RYLAKQALADNQEVLMVSRGCVS-------------------------------------
>tr|A0A0K2TIG4|A0A0K2TIG4_LEPSM Anoctamin OS=Lepeophtheirus salmonis PE=3 SV=1
----------------------------------------DT---------MECADFEGMRIDFILVWNESGNAK-------------------------
---------------------IASAERRRVFESNLQKEGLVLEHLPR-EPSGLHFIKIHAPDTVLKRYAEILKLRLPMKFD----F-RV-------V---
-VESFRVDQKLFK--KANELTATFSRDKEYLFDT-DDPDFFAPYMRSRI-EFILKRKRISD-D----IDRCLSDGTYTASYPLHD--------STGTRKL
LYEEWASFSKILKYQPIDAVRDYYGVKIAIYFAWLGFYTNLLIPPAIFGFIVFIYGVLSL-YDIPSQSLCRELQTLYMCPAC-VFCDYWDLRESCLHSKI
MYLFDNEMTIVFAIFMSFWA-LFLEFWRRYSEEITHRWNVRGYDPEE----EHPRPKYLAQLKDVK-----INTEPF-----WKRKFPGLLLSVSTVIFM
ICLGFV-VVG-ILYRMSMVVALSLVNEETIK--ASLFISSTGASINLVCILIFNQVYGYVAIQLTELELHRTQTQFDDSLSLK---LQFVNYYASIFYIA
FFKG--VGYPGNYI------RQEECSPGGCYMEVCLQMAIIFVGKQFL-LSVVEYQLPRIWKILNTLTV---MA----EEKCVYPQWIQDYKLVEYQGLF
YEYLEMVIQYGFITIFVTAFPLAPLFALLNNLFELRLDAKKLLVHHRRPVAQRVKDIGVWLNILDSVGRIAVLTNGLIIAFTSDFVPRMLYKLRYSE--T
LKGYLNFTLSKFNPNDFSTTS---------LT-EYCFYHGYRYPPGH-KEYEVTQVFWHVMAARLCTVVVYQNFVNMSVMAIRWIIPNFNTGLKEKIRRE
AYLTNEIIIRTELLKAKGELDAN-------------------------------------
>tr|A0A0L0CAW4|A0A0L0CAW4_LUCCU Anoctamin (Fragment) OS=Lucilia cuprina GN=FF38_01525 PE=3 SV=1
--------------------------------------------------AQRHFEDGIREVDFVIGFHHFDIQF-------------------------
----------------------DHVKKRHIFERNLAKEGLQVELDFT---QCIHFIKIHAPQEVLYSYAEILKIKMPM-------E-FL-----------
-VPCFKLSPTKFP--KQKRIYSEFQINHKSLYDS-QQSSFFDAGTRNSI-YFILERLHFSDD-----IEKLLAEGVYTCAYTLHD-----------DRNL
LLNEWATVNRLLHNQPLDHIKEYFGAKIAIYFAWLGFYTNMLIPLSLIGLLYLLFGFLTR-WDTVSKEICDH-RTIIMCPSC-RLCDYWELKEICIAAKV
NYLIDNYGTVGYAFITSIWDALFLELWKRYVAKLVHKWGLTGYTQEL----EHARPQFLAKLKKNKKLA----FEPF-----WFTKCLPSITNYSILLLF
ICISLM-TIS-IVYRMAQRAAQNIVGTD-PV--TVFYFPMASTVIELSMITALANIYNSLAIVLTNWEYCRTQKEYDESVTTK---FHFINYYSSLFYIA
FIKG--VGYPGKYN------RREECHHGGCLLELSIQLTIIMLGKQVF-FGMLEMLMPPLKICLSLISSRRGE------SLQGNNQWCKDYYLLAWNMMY
LEYLEMVIQYGFVTLFGLAFPLAPLLALINNLFETRLDAYKMLNYLRRPVAQRACDIGVWLGFLNMITKLAVASCAVLIAFSTNFITKLVYISIISK--T
LKGYTDFVLSHFNTKDFELQP---------LN-EVCRYWDFRNPPSS-RPFERPMIYWQILAAKLVFIVLYQNFIGLIQNIISWSIPDVSRDLQKRIDRE
NYLLREFIIEYEKLLALEQNYEL-------------------------------------
>tr|A0A0K8TMI8|A0A0K8TMI8_TABBR Anoctamin (Fragment) OS=Tabanus bromius PE=2 SV=1
--------------------------------------------------TWRRFQDGERSVDFILAYRGDDN-N-------------------------
---------------------PQNLIKRRIFEGNLESEGLELEREK---TQKIHFLKIHATHGTLCQYSEILKVKMPIRLKQE---------MKS-----
---FVKVDKS-LF---EHALKFEFSRAYDY-FDT--DPSFFDASTRSMV-QFILDRQKFTEDG----IQRLINDGVYTAAYPLHD-------ITGSQRNL
LLNEWASVRQWIRHQPLDTIKDYFGVKIALYFAWLGFYTHMLIPASIVGLICFFYGLITLSSDTVSQDICHDNNTILMCPQC-VKCDYWYLKETCVYSKI
SYLFDNNFTVVFAFFMSFWA-LYLELWKRHSANIIHRWGLTDFCYQA----EHPRPQYLARVRNSKKT---FNLEPF-----WKVRFPTYLMSFSAVFLF
ICLALA-VFA-VLYRMSLTASRSYY-GT-TM--KIMVLPATGAVINLVAITILNYIYDYLAIYLTNIEYRRTQTEYDESLALK---FQFVNYYSSIFYIA
FFKG--VGYPAKYNR-----RQEECSPGGCLMELCIQLVIIMVGKQAM-NSILEMLIPWIFKKFKS-ITTKFGI-TEEACLISCNQWTEDYKLLAWRGLF
DEYLEMIIQYGFITLFVVAFPLAPLFALINNVLEMRLDAKKFLKFYRRPVPQRVNHIGIWYNIMSILGRLSVGSSAFIIAFSSNFIPMMVYKIIVN--GT
TSGYLNYTLAQFNTEHFESNYNVS----MSQNVTTCRYADFRNPPDDPRRYKRPIIYWHILAARLAFIVIFQNIVEVVQMLVAWAIPDVPGKLRDRIKRE
DYLTREIIIEQEKKRPKSQTPTP-------------------------------------
>tr|W5JVK2|W5JVK2_ANODA Anoctamin OS=Anopheles darlingi GN=AND_001144 PE=3 SV=1
----------------------------------------MS-TMPTEEVTWRYFQDQKRIVDFVLAFNSQTVTDT------------------------
---------------------QIAYAKRMLFQQNLEQEGLQIETES---CQRIHFVKIHVPEQVLSQYCEFLKTKMPMKLA----D-KI----DFSI---
-QSSNRIHQDIFK--SEYRLLYEYSRNKPYLFDD-HDPNFFTPSVRIAV-NFILKRTSFSDKQ----IQRLIEDKVYLDAYPLHD--------SRCQRTL
LLQKWASIKKCVKPQPLDHIKEYFGVNIAMYFAWLDFYTHMLIPAAIAGLICFFYGLFTY-NNWMSREICRD-DSTIMCPQC-ENCDYWYLNSTCTISKF
AHIFDNDMTIFFSVFMSIWA-IYLETWKRYSSKIQHRWGITEYSSKL----EPPRPQYLARLADVKK----FNHEPF-----WTKKFPSFVFSYSVIFLC
MLLTIA-VFG-IVYRMSLMTSRNIYGVQGSP--KLITFPAVTATINLAFSTLISWLYKHVAVYMTNIEYRRTQTEYNESLNLK---FEFVNYYSSIFYIA
LLKG--PGYPGKYS------RQEKCSPGGCLMELCIQLAIIMIGKQAI-AAVKENVIPFLVQKFKEFRSVLCIR---DEQLISYNQWAKDFNLINWRTLF
KEYLKMVIQYGFITIFVVAFPLGPLFALLNNVLETRLDARKFLLYYKRAVPQRARDLGIWYNIMHVVGKLAVITSACIIAFSSNFIPRMMYKLTVSS--T
HEGFINHTLAYFNVADFEDN----------SN-TICRYSGYRNPPDH-QPYELTTMYWQILAVRVAFVVIYQNLVGFMQIVLAWAIPDVPEWLQDQIKHE
RYLTNEHIIEQEKLKMLNIASAA-------------------------------------
>tr|A0A084VQW9|A0A084VQW9_ANOSI Anoctamin OS=Anopheles sinensis GN=ZHAS_00007745 PE=3 SV=1
----------------------------------------VYFSSLPNNQCCRYFDDQTTIVDFVLAYKPQTDS--------------------------
----------------------INNERRQKFIDKLTKAGLITEKDA--SQDDTHYVKINVPDKILKKYCEFMKMKLPMKLD----D-RI----KVSP---
-RG--RFNPTKRP--VEYRLLHEYSESKSYLFDE-KRGNFFSTGIRIAV-NFILERSSFKEKP----IRQLLKEHPFYAAFPLHD------DTTRSIRAR
LLVDWASVKKCLTYQPLDDIKEYFGVKIALYFTWLGFYTAMLAPAALVGFLCLLYGILTF-TNRISKEVCND-STTIMCPQC-KYCGYWYLNSTCMISKI
AYIFDNEATIFFSIFISVWA-LYLKLWKRYVSRIQYRWGVLDYCSMA----EPPRPEYSARVKNCKR----YNEESF-----WTQKLPTVICSYSVVYVL
ISMTVA-VFG-IVYRMSLKTSEKFYGDSATV--KLIVFPMTTATINLLVSTFLTQLYKKVAKKMTDIEYRRTQTEYNDSLNVK---FDFINYYSSIFYIA
FLKG--PGYPKEYN------RQEECSTGGCMVELTIQLATIMIGKQLI-AIIKEYFIPFLKQKYKTLITWYYTN---MELPQSSGQWIRDNKLLSWLSLF
KEYLKMVIQYGFITIFAVAFPPASIFALVNNMIETRVDAQKYLQFYKRAVPKRVRNLGMWYKAMQVITKIAVISNAYIIAFSSNITHRLIYMLFVNP--T
DEGFVNHTLAYFNTSHFEAA----------KNVEICRYAEYRNPPES-NPYERSLLYWKILAIRLALMVIYQNLVGVVQEKKRTTAI-------------
TYVHMER-----------------------------------------------------
>tr|H2TU13|H2TU13_TAKRU Anoctamin (Fragment) OS=Takifugu rubripes PE=3 SV=1
----------------------------------------------------------------------------------------------------
------------------------------------------------------FTRLHAPWPVLCREAEFLKIKVPTKTSYKLKEESGFGSRMSSVWRT
LKQPFQPKVPHQDQESTKFLSHCFSR-----YNITSKDTFFDNATRGRIVYEILRRTVCARTCQTI-ISTLIAKGVYDAAFPLHDGDFAVVVEEKNDRQV
LHQEWARYSAFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQLLIPASVVGIIVFGYGVATMNTNIPSQEMCDDSLNFTMCPLCDGACDYWHLSTACGTARA
SHLFDNPGTVFFAIFMSLWAVLFLEQWKRRQISLSFSWDLTGIEEDE----VETVTCPVLC--CS----PASP------PRPRYDNVPVFLISSNTGPCW
FGLTFSAVFGVIIYRITVSALMAMSPDPETKSNVRVTVTATAVIINLVVILILDEIYGSVALWLTELEIPKTETNFEERLILKAFLLKFMNAYAPIFYVA
FFKG-FAGRPGNYVYVFNDYRMEECAPGGCLIELCIQLSIIMLGKQLIQNNIFEIGIPKLKKLFRELKNKSPA-ARE-E-ERPPQQWNLDHDLAPFEGLT
PEYMEPVIQFGFVSLFVASFPLAPLFALLNNVIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILSGMGKFSVIINAFVISFTSDFIPRLVYQYMFSQTGT
MHGFIDHTLSHFNVSNFKPGTAPENSEH--GNITVCRYKDYREPPWSPDAYAFSKHYWCVLAARLAFVILFQNLVMFLSLVVAWIIPDVPKTIVEQLKRE
KKLLVDVFLQEEKEKFQLIQSLF-------------------------------------
>tr|F6SJY7|F6SJY7_MONDO Anoctamin OS=Monodelphis domestica GN=ANO7 PE=3 SV=2
-------------------------------------------MSKQELGRGKWCGWGRPRTDFVLVWEEKLWLPGRG----------------------
---------------------RQQQRWRGKFQRNLQAAGLLLEE----EQRAVHYLKLSAPWEVLIYYAEDLCMRAPLQ---------------------
---RL-----RLP--PLGFYTCAFRRSKLSKFLGDAPESYFSNTQRHRV-AEILARTA---------IARLLAEGVYTAAFPLHEPGYP--GADLNPRQL
LYSYWARWRCWHKYQPLDHVREYFGEKVAIYFAWLGFYTAWLLPAAIVGTLVFLSGLLTIGTNTPAKEICASGGTFVMCPLC--TCATWNISEICPMAKL
GYLFDNPGTVFFSIFMSFWA-AFLEHWRRKNATLAHHWDCADFQEEE----ERPRPEFAAMAPQ-------QNKEPP------RARLSRMVTGSMAILVM
LCVVMI-LVS-IMYRGIVSIVMFHT--NPLM--AGNIANISSTFLNLVLILLMGKVYTSLAEQLTKWEMHRTQTLHEDAFTFK---FQFVNFYSSPFYVA
FFKG--VGYPGQYG------RNED-GPGGCLIELAQQLFIIMVGKQLA-NNVEEFVLPKIKAWWQKRQLAGLWG----M-GHDPRRWEDDYELIEC-GLF
EEYLEMVLQFGFITIFVAAFPLAPLFALLNNWVEIRLDAHKFVCEYRRPVAERAQGIGVWLLILETMAHLSVIVNAFLIAFTSDFLPRLLYQYEHH----
LQGYVNFTLAQA-----PHTYLAQG------NHTPCRYKAFRDETGN-----FTLFYWKLLAVRLGFILAFEHVVFFFLRLIAWLVPDVPAELALQVKRE
RYLAKQALADNQDALFSMK-----------------------------------------
>tr|G1MT92|G1MT92_MELGA Anoctamin (Fragment) OS=Meleagris gallopavo GN=ANO5 PE=3 SV=2
----------------------------------------PQIDKRHESKDSIFFRDGVRRIDFVLSYVDDLNKEWEKKK--------------------
---------------------RVREERRKEFESNLQKAGLELETEDKKEDGKIYFVKIHAPWEVLITYAEVLNIKVPIRND-------------------
---PFRLPEKVM---EPDYFTAPFSKD----YLINDESTFFSPSMRNRI-NYILTRCPYGTEE----IKRLLNNGTYSAAYPLHD----KAPNCDNERYT
LYMEWARFLRFYKEQPLDLIRKYYGEKIGIYFAWLGFYTEMLFLAAVVGVICFLYGLFTMD---N-KEICDPAGEIIMCPLCDRECEYWRLNTTCQSSEY
SHLFDNVATLFFAIFMGIWV-LFLEFWKRRQARLKYEWDLVDFEEEQ-------RPEYEAKC---------KNMEPLT-------QAVRF-ISGTTVLFW
VSLIIA-MIA-IVYRLAVYAAFASLENTQLQ--PQLATSVTASCLNFVIIMILNFIYEKIAIWITDM--PRTHMEYENRLTMK---FQFVNYYSSCFYVA
FFKG--VGYPGAYTYMFNRW-NEECDPAGCLIELTTQLTIVMAGKQIW-GNIQEAIVPWICNWWGRRK-------RSNPENL-YSRWEQDHDLQTFLGLF
YEYLEMVIQFGFITLFVASFPLAPLLALMNNILEIRVDSWKLTTQYRRPVAAKAHSIGVWQEILNGMAILSVVTNAFIVAFTSDMIPRLVYYYAYSE-SP
MSGYINNSLSVFEISDFPERNKPK--ENPE--FEQCRYRDYRYPPDHERKYLHTMQFWHILAAKLAFIIIMEHVVFIVKFFVAWMIPDVPADVKAKIKRE
KYLTQKILHEYELEKLKERLCQG-------------------------------------
>tr|H3C3C4|H3C3C4_TETNG Anoctamin OS=Tetraodon nigroviridis GN=ANO2 (2 of 2) PE=3 SV=1
----------------------------------------------------LFFSDGRRKVDYILCYKSKERRA-------------------------
--FKHRL-------SISS--NEEKALMREDFEAGLVEAGLQIERDKENNNQGQTFIRLHIPWPILSREAELQKIKVAVKKKCELRKRTGIAGLWDSFVTK
VNTPFQPDTPDFDTHHFKTLKHPFIRDKLHLYDIKSTETLFDNATRSRIVAEIISRTSCRQPYQT--INSLIARRVYDSAFPLHDGSFTRRKDQRNDRQL
LHEEWANYGVMHKYQPVDLIRKYFGEQIGLYFAWLGVYTQLLIPPSVLGIIVFLYGIFTVDDNVPSQETCNDSLNITMCPLCDGVCDYWHLSTVCSLARA
SYLFDNGATVLFAIFMSLWAACFLEHWKRRQMCLKHSWDLTSLEDEEERVQEELRPEYEEALQEKKIKLKAT-CGQEPDSLDVEDHLSGYLVNVATLLFL
IFVTFSAVFGVAVYRICMLSVWSMNPDPEAKASVRMTVTTTGIILNMLVVLVLEEVYGAIAVWLTETELPKTTEEFEERLIVKSFFLKSMNAFAPIFYVA
FFKG-FAGRPGDYVYVFGDYRMEECAPPGCLIELCIQLSMIMLGKQLIQNNVFEVLIPKLKKMYRTIQEEKGKKNEKEEEKRPKQQFDKDYVLEPFEGVG
SEYMEMIIQYGFVSLFVASFPLAPAFALLNNVIEIRLDAAKFVTEIRRPDAVRCKDIGIWYNILCGISKFSVITNAFVISFTSEFVPRMIYQYMYSTNGT
LNGYTDHSLSYFNVSDFPPGTAPTTTLIT-GVSVCR-YKDYRDPPWKPDAYTQSKEYWSVLAAKLAFVIFFQNLAMFLSMLVAWMIPDVPRTLREQLKKE
NMMLMEFLLNQDQE----------------------------------------------
>tr|I3LFE1|I3LFE1_PIG Anoctamin OS=Sus scrofa GN=ANO5 PE=3 SV=1
------------------------------------------FKKDEQSKDSIFFRDGIRQIDFVLSYVDDIKKEAELKA--------------------
----------------------KRKMRRKEFEQNLRKTGLELEIEDKMEDGRTYFVKIHAPWEVLVTYAEVLGIKMPIKSD-------------------
---PLKLPKNVK---HPEYFTAQFTRH----FLIENESSFFPSSARNRI-YYILSRCPFGIE-----IERLLNSHTYSAAFPLHD----PSPNPVNERYI
LCQNWARFSYFYKEQPFNLIRDYYGEKIGIYFVFLGFYTEMLFFAAIVGLVCFIYGLFSMH---NSTEICDPEGQIIMCPLCDLMCDYWRLNSTCLASKF
SHLFDNESTVFFAIFMGIWV-LFLEFWKQRQARLEYEWDLVDFEEEQ-------RPEFEAMC---------MNMEPLC-------SIPWY-LSGATVTLW
MSLVVA-MVA-IVYRLSVFATFASFESEALK--PQITTSLTGSCLNFIVILILNFFYERISAWITKM--PRTHQEYESSLTLK---FQFVNFYSSCFYVA
FFKG--VGYPGKYTYLFNVW-SEECDPAGCLIELTTQLIIIMTGKQIF-GNVKEAIYPLVLNWWRRRK-------RTNSEKL-YSRWEQDHDLETFLGLF
YEYLETVIQFGFVTLFVASFPLAPLLALLNNIIEIRVDAWKLTTQYRRPVAAKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDMIPRLVYYYAYST-QP
MKGYVNNSLSTFLIADFPNYTVPSEKRDF-T----CRYRDYRNPPDHEDKYFHNMQYWHVLAAKMTFIIIMEHVVFLMKFLLAWMIPDVPKDVLERIKRE
KLMTVKILHDFELNKLKENLRIN-------------------------------------
>tr|K7GAR2|K7GAR2_PELSI Anoctamin OS=Pelodiscus sinensis GN=ANO5 PE=3 SV=1
----------------------------------------LRISKKHQSKDSVFFRDGVRRIDFVLSYVDEPNKEEEKKV--------------------
-----------------------------EFEKNLQKSGLELETEDKKEDGKTYFVKIHAPWEILITYAEVLNIKVPIRND-------------------
---PFRLPEKVM---EPDYFTAPFSKS----YLIHDENTFFSPSIRNRI-YYILTRCPYGTEE----IKRLLSNGTYTAAYPLHD----KAPNCDNERYT
LYMEWARFLRFYKEQPLDLIRKYYGEKIGIYFAWLGFYTEMLFLAAVVGLICFLYGWFTMA---N-EEICDPEGKIIMCPLCDKKCEYWKLNTTCESSKY
SHLFDNVATLFFAIFMGIWV-LFLEFWKRRQARLKYEWDLVDFEEEQ-------RPEYEAKC---------KNVEPLT-------QTVRF-ISGTTVLFW
ISLIIA-MTA-IAYRLAVYASFAQIETTQLQ--PQLATSVTASCLNFVIIMILNFLYEKIAVWITDM--PRTHLEYENRLTMK---FQFVNYYSSCFYVA
FFKG--VGNPSNYTYMFGSL-NEECDPAGCLIELTTQLTIVMAGKQIW-GNIQEAIVPWIWNWWGRRK-------RCNPENL-YSRWEQDRDLQSFLGLF
YEYLEMVIQFGFITLFVASFPLAPLLALMNNILEIRVDSWKLTTQFRRPVAAKAHSIGVWQEILNGMAILSVVTNAFIVAFTSDMIPRLVYYYAYST-SP
MSGYINNSLSVFQISDFPANKTPE--NNPE--FLTCRYRDYRNPPGHEKQYLHTMQFWHILAAKMAFIIIMEHIVFIVKFFVAWMIPDVPADVKARIKRE
KFLTQNILHEYELEKLKQKLCEC-------------------------------------
>tr|I3K1C2|I3K1C2_ORENI Anoctamin OS=Oreochromis niloticus GN=LOC100697197 PE=3 SV=1
---------------------------------------------------GLYFSDGRRKVDYVLVFHQRRHTSIRSPASAS-----------------
-VSQDRL-------SIVS--NHEMRLIRQEFEANLIEAGLEIERD---KSHGPSFTRVHAPWPVLCREAEFLKIRVPTKTSYELKEETGFGSSMSTVWRT
LTKPFQPKVPHQDHGRTKFLSHCFSRDKLHLYNITSKDTFFDNATRGRIVYEILRRTVCARTCQTI-ISTLIAKGVYDAAFPLHDGDYKVILEERNDRQV
LHEEWARYSAFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQLLVPASIVGIIVFGYGVATMDTNIPSLEMCDQRLNFTMCPLCDQACDFWHLSTACGTAKA
SHLFDNPATVFFAIFMSLWAVLFLEQWKRRQISLSFSWDLTGIEEDELLLQEHPRPRYETILLQKRQKKQNNESALDREKLTWKDRLPGYLINVSSILFM
FALTFSAVFGVIIYRITVSAIMAMSPDPEIRHNVRVTVTATAVIINLVVILILDEIYGAVAVWLTELEIPKTETNFEERLILKAFLLKFMNAYAPIFYVA
FFKG-FAGRPGNYVYVFNDFRMEECAPGGCLIELCIQLSIIMLGKQLIQNNIFEIGIPKLKKLVRTLKEKETT-KRE-E-EKPPQQWNLDYALAPFEGLT
PEYMEMIIQFGFVSLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAARAKDIGIWYNVLSGMGKFSVIINAFVISFTSDFIPRLVYEYMYSPTGT
MHGFIDHTLSYFNVSDLKPGTAPQNSEL--GNITLCRYKDYREPPWSPDAYQFSKQYWCVLAARLAFVILFQNLVMFLSLVVAWVIPDVPKTIVEQLKRE
KKLLVDVFLQEEKEKLQLIQSLF-------------------------------------
>tr|I3JNH6|I3JNH6_ORENI Anoctamin OS=Oreochromis niloticus GN=LOC100690910 PE=3 SV=1
----------------------------------------SEIDKQKYSKDSVFFRDGVRRIDFVLSYIDDKDDQ--RKQ--------------------
-------------------------ERRRVYESNLQKVGLELETEDKTEDGKTYFVKIHAPWEVLATYADVLKIKVPFKND-------------------
---PFRLPEHIM---EPDYFTAPFNKS----FLIEDKETFFPPSTRNRI-YYILARCPYFKDE----IKRLLNNGTYTAAFPLHD----KSPNCESERFN
LYKYWAKFFCFFKEQPLNLVRKYYGEKIGIYFAWLGFYTEMLFFAAVVGTICFVYGFLTYD---N-KEICSEEGNIVMCPLCDQKCTYWRLNITCNSSWQ
SHLFDNVATVFFAIFMGIWV-LFLEFWKRRQARLEYEWDLVDFEEEQ-------RPEYETKC---------LNMEPIT-------KCARI-LSGATVLLW
ISLIIA-IIG-IAYRLAVYASFASIKNNTLD--PQLATSVTASCINFVIIMILNLLYERVAIKITDM--PKTHLEYENKLTVK---FQFVNYYSSCFYVA
FFKG--VGYPGNYTYMFGS--NEECEPGGCLIELTTQLVIVMTGKQVW-GNIQEALVPWLMNWWGSRK-------RSHPESL-YSRWEQDYDLQGFLGLF
YEYLEMVIQFGFITLFVASFPLAPLLALINNIIEVRVDAWKLTTQFRRPVAAKAHSIGAWEEILGGMAVLSVVTNAFIVAFTSDMIPRLVYMYAYRT-LN
MKGYINNSLSVFNISQFTLEERPE--EYPSSI-TTCRYRDYRYPPDDKKRYEHNMQFWHILAAKLAFIIIMEHVVFMVKFFVAWMIPDVPSDVRARVKRE
RYLVQEYLHNYEVEKLKIQLSQN-------------------------------------
>tr|G3WGN3|G3WGN3_SARHA Anoctamin (Fragment) OS=Sarcophilus harrisii GN=ANO5 PE=3 SV=1
----------------------------------------LMFDKRQQSKDSVFFCDGIRRIDFVLSYVDDPKQEGEKKK--------------------
---------------------K------KVFSLLLMKSGLELETEDKKEDGRTYFVKIHAPWEVLTTYAEVLNIKMPIRND-------------------
---PFRLPKKVM---EPDYFTAPFSKQ----FFIEDENTFFSPSVRNRI-YYILSRCPYGTEE----IKRLLTNGTYTAAYPLHD----KAQNSGNERYT
LYTEWARFLRFYKEQPLDLIRRYYGERIGIYFAWLGFYTEMLFFAAVVGAICFFYGLVTMT---NLVKICNESGAIIMCPLCDVKCEYWKLNTTCESSQY
SHLFDNVATLFFAIFMGIWV-LFLEFWKRRQARLEYEWDLVDFEEEQ-------RPEYEAKC---------KNLEPLT-------QALRF-FSGATVLFW
ISLIIA-MIA-IVYRLSVYAAFASIENTELQ--PQLATSVTASCLNFVIIMILNFLYERIAVWITDM--PRTHLEYENRLTMK---FQFVNYYSSCFYVA
FFKG--VGYPGAYTYMFSKW-NEECDPAGCLIELTTQLTIIMAGKQIW-GNIQEAILPWVWNWWRRRR-------RTNSEKL-YSRWEQDHALQSFLGLF
YEYLEMVIQFGFITLFVASFPLAPLLALMNNILEIRVDSWKLTTQYRRPVAAKAHSIGVWQEILNGMAVLSVVTNAFIVAFTSDMIPRLVYYYAYST-SP
MSGYINNSLSVFQISDFPNTTLPA--GSTG--FTTCRYRDYRYPPDHEKKYLHTMQFWHILAAKMAFIIIMEHIVFIVKFFVAWMIPDVPSEVKARIKRE
KFLTIQILHEYELNKLKENLCNR-------------------------------------
>tr|F6TYB8|F6TYB8_ORNAN Anoctamin (Fragment) OS=Ornithorhynchus anatinus GN=ANO5 PE=3 SV=1
----------------------------------------LMFDKRHQSKDSVFFRDGTRRIDFVLSYVDDPKQEGEKKV--------------------
---------------------E--------FEKNLLKAGLELETEDKKEDGKTYFVKIHAPWEVLATYAEVLNIKMPIRSD-------------------
---PFRLPEKIM---EVDYFTAPFSKQ----FIIEDENSFFLPSTRNRI-YYILSRCPYGTEE----IKRLLSNGTYTAAYPLHD----KAQNCGNERYT
LYTEWARFLRFYKEQPLDLIRRYYGEKIGIYFAWLGFYTEMLFFAAVVGAICFFYGLFTMD---N-KEICDSSGKIIMCPLCDEKCEPWRLNSTCASSEY
SYLFDNVATLFFAIFMGIWV-LFLEFWKRRQARLEYEWDLVDFEEEQ-------RPEYEAKC---------KNMEPLT-------QALRF-FSGATVLFW
ISLIIA-MIA-IVYRLAVYAAFARFENAQLK--PQLATSVTASCLNFVIIMILNFLYERIAIWITDM--PRTHLEYENRLTMK---FQFVNYYSSCFYVA
FFKG--VGYPGSYTYMFSRW-NEECDPAGCLIELTTQLTIIMAGKQIW-GNIQEAIVPWIWNWWRRRK-------RTNSEKL-YSRWEQDHDLQSFLGLF
YEYLEMVIQFGFITLFVASFPLAPLLALMNNILEIRVDSWKLTTQYRRPVAAKAHSIGVWQEILNAMAILSVVTNAFIVAFTSDMIPRLVYYYAYSV-SP
MAGYISNSLSEYQIPIVANSTITS--NTSV--YSICRYRDYRYPPSHEKKYEHTMQFWHILAAKMAFIIIMEHIVFVVKFFVAWMIPDVPEEVKARIKRE
KFLTIKILHEYELNKLKENLCER-------------------------------------
>tr|Q6DDQ3|Q6DDQ3_XENLA Anoctamin OS=Xenopus laevis GN=ano5 PE=2 SV=1
----------------------------------------SEIDKHVQSKDSVFFWDGIRRIDFILSYTDETNKEAEKKA--------------------
---------------------D--------FEFNLHKSGLELETEDKKENGKTYFLKIHAPWEVLTTYAEVLNIKMPLKDD-------------------
---PFKLPPEVM---EPDYFTAPFRKD----FRIEDKEKFFTPSTRNRI-YYILSRCHYGEEE----IKRLLNNGSYLDAYPLHD----KTRSC--ERYT
LYSHWAKFTRFYKEQPLDLIRKYYGEKIGIYFAWLGFYTEMLFYAAVVGFFCFLYGWITMD---S-KEICDPGGQIIMCPLCDKRCEFWRLNSTCEPSQY
SHMFDNVATLFFAIFMGIWV-LFLEFWKRRQARLEYEWDLVDFEEEQ-------RPEYEAKC---------KNMEPPS-------KAVRF-FSGATVLFW
ISLIIA-IIA-IVYRLWVYAAFASIENNLLE--PQLATSVTASVLNFITIMILNFLYERVAIWITDM--PRTHLEYENRLTMK---FQFVNYYSSCFYVA
FFKG--VGYPADYTYLFGKW-NEECDPAGCLIELTTQLTIVMAGKQIW-GNIQEAFVPWTWNWLKRRK-------RNHPENL-YSRWEQDGDLQTFLGLF
YEYLEMVVQFGFITLFVASFPLAPLLALLNNILEIRVDSWKLTTQFKRPVAAKAHSIGVWQEILNGIAILSVVTNAFIVAFTSDMIPRLVYYYAYTQ-MP
MSGYISSSLSIFNVTDFKEQSMPT--KNDM--VLSCRYRDYRYPPGHGKEYQVTMQYWHILAAKMAFIIIMEHVVFLVKFFVAWLIPDIPSEVKARVKRE
KFLTQKILHEYELEKLKEKLSNK-------------------------------------
>tr|A0A069DXF7|A0A069DXF7_9HEMI Anoctamin (Fragment) OS=Panstrongylus megistus PE=2 SV=1
----------------------------------------MEQNCTSPEIKSTMFRDNMRTVDFVLA-WLEGK-G-------------------------
---------------------ADLQIKREAFEKRLEEEGLILERDC---MDRLHVVKLHAPVEVLKRYCEILKLRMPMKIPTE---------VKS-F---
---CVRLDTS-VF---KFRLTAEYSRHKSY-FAE--SEHFFSPQIKTIV-DFILERTCFSLET----IQKLISDGVYKAAYPLHD-------DPTCLRGL
LLKEWALVNRWAMYQPIDQIREYFGVKFALYFAWLGFYTHMLVPASIVGLLCFLYGCFTIFSDRLTNDICNESLNITMCPLC-RTCDYWKLSDTCTYARF
TYLFDNPATIVFAVFMSFWA-LFLELWKRYSASVAHRWGLTDFCLQS----EPPRPKYLARLATNKKSK--TNKEPF-----WSVRLPAVMLSFSVVFLL
VLVAVA-VFG-VLYRMSVLASVSLVEDQ-SA--AMFIIPATAAMINLVFIITLNFVYDKIAVFLTELELLRTQTEFDESLTVK---FQFVNYYTSIMYIA
FLKG--VGYPAKYNR-----RQEECNPGGCLMELCIQLAIIMIGQQAV-NGVIEMTLPLVYKWLNT-LTMKAGLDDTAIVDPTHKQWTEDYKLLDYRGLF
YEYLEMVMQYGFVTIFVSAFPLAPLFAMINNIFEMRLDARKFLTYYRRPVPRRAPNIGVWFRILNVLGRLAVISNAFIIAFSSTFIPKLVYKMTISP-HT
DEDFLQHSLAWFDTRDFADGTAPR----FP-NVSYCRYSAYREPPDGLRPYKRTDLYWHVLAARLGFIVAFQNVVSLVMIAVQWCIPDVSPKLKDQIKRE
AYLTSELIIQHETLRAKQGSGDA-------------------------------------
>tr|J9K6P9|J9K6P9_ACYPI Anoctamin OS=Acyrthosiphon pisum GN=LOC100165230 PE=3 SV=2
---------------------------------------------IRPESITFDSTPGDISVDFVLVSSSKAK-A-------------------------
---------------------IDGWNRRSAFEERIKEQGLLLEEDV---VGGLTFVKVHAPIPVLRRYCEILKLRMPMKYPEK---------IKK-V---
---FITIDPG-PF---KYILTAEYSREKSY-FNE--DPEFFSAEVRTLV-DFILNRVSWGKDQ----IQCLLDGGVYRAAYPLHD-------TENSLRHQ
LYVEWAMMSKWIRKQPIDQIKEYLGVKYAFYFTWLGFYTHLLIPAAILGLIVFFYGIFTFPNNRFSSDICNDK-DTIMCPLC-RTCDYWELSNTCFYARL
TYLFDNDLTVIFAFLMSIWA-LFLELWKRYSATITHRWGLTGFTFEA----EHPRPQYLARLAGSNHT---VNIEPL-----WK-KIPATLFSISVLLLL
IMVAIA-VFG-VLYRMSVLASLSLTNQS-MS--SNIFIPTTAAIINLVCIQLLNFVYDKVAIYLTEMELLRTQTEFDESLTIK---FQFVNYYTSIIYIA
FLKG--VGYPAKYLR-----RQEECSPGGCLMELSIQLFIIMVGQQAL-NTVVEMIIPVGLNWFNS-LTENTGRSEEDLATAVKKPWIEDYKLLDWRGLF
PEYLEMVMQYGFVTLFVTAFPLGPFFALLNNVFEMRLDAKKFMKYFRRPIPHRVPNIGVWYRVLDILGKLAVITNAFIIAFSSNYIPRMVYISLVSE-NT
DKGFLNNTLAYFDTKDFESGIAPL----SSTNVTYCRYKDYRNPPWSPQKYERPTFYYEVLVARLTFIVIFQNIVSLVKVAVQWLIPDVPNALSDRIKRE
SYLTTQMIIKNEAKKAAEV-----------------------------------------
>tr|A0A0F8AK08|A0A0F8AK08_LARCR Anoctamin OS=Larimichthys crocea GN=EH28_08795 PE=3 SV=1
----------------------------------------AQLVEYNDKPDSLFFNDGERRIDFILVYEDEDKKEF--EK--------------------
---------------------QRRKRRREYFEASLMKMGMELEATQ--TNDKLMFVKVHMPWDVLCTYAEVLHIKLPIQND-------------------
---PFYPNENLI---EAEYFTAPFEKD----FHIRDKDMFFTPAMRSRM-YYILSRAPYEIR-----ITKLLDSGVYKAAYPLHD----KSQDCPNERYL
LYQEWAHPKSFYKMQPLDLIRKYYGEKIGIYFAWLGFYTIMLALAAVVGLGCFIYGYKTQE---S-KEVCDPEGKIVMCPQCDRECKYWRLNSTCEASKK
LCIFDNFGTLVFAVFMAIWV-LFLEFWKRYQAELEYEWDTVEFL--E-------RPEYEAKC---------KNVKPYT---TC--RCVRV-IGIGTVLFW
IMLIVA-IVA-TIYRLAAFFAFSARRA--LE--PQMATSVTASLISFVVIMILNLLYERFAIWITDF--PRTKTDYENSLTLK---FQFVNYYSSCFYIA
FAKG--VGFPGDPVYLMGKY-NEECDPGGCLIELTTQLSVIMGGKAIW-NNIQEVLLPWLKNMLSRY-------CRVASEKV-IPRWEQDYQLQPVLGLF
YEYLEMVIQFGFVTLFVASFPLAPILALVNNLFEIRVDAWKMTTQFRRIMPEKAQHIGAWQPILQGIAILAVATNAMIIAFTSDMIPRLVYYYPYGD-NT
MQGYINSSLSIFNTNDFS-NYS-RP------------YRDFRYPPGHPKQYEYNIYYWHVIAAKMAFIIVVEHIVYLTKFILSYVIPDVPYAVKEQIKRE
KYLTQVILHETNLKLVSKRLIPG-------------------------------------
>tr|G3Q4R9|G3Q4R9_GASAC Anoctamin (Fragment) OS=Gasterosteus aculeatus PE=3 SV=1
--------------------------------------------EFNDKPDSLFFNDGVRRIDFILVYEDEDKKEF--EK--------------------
---------------------QRHKRRREYFEASLMEMGMELEATK--IDDKLLFVKVHMPWDVQCTYAEVLHIKLPIQND-------------------
---RFYPNEDLI---EAEFFTAPFEKD----FYVRDKDVFFTASMRSRM-FYILSRAPYEIR-----ITKLLDGGVYKAAYPLHD----TSESCPNERFL
LYEEWAHPKSFYKMQPLNLIRKYYGEKIGIYFAWLGFYTRMLALAAVVGLSCFIYGYKTQE---S-KEVCSPDGNIVMCPQCDRECNYWKLNSTCEASKK
LCIFDNFGTLVFAVFMSIWV-LFLEFWKRYQAELEYTWDTVEFL--E-------RPEYEAKC---------KNVKPHT---AC--RCVRV-IGIGTVLFW
ILLILA-IVA-IVYRLAAFFAFSAKRA--LE--PQMATSVTASLISFVVIMILNILYERVAIWITDFT-PRTKTDYENSLTMK---FQFVNYYSSCFYIA
FFKG--VGHPGDPVYLLGKY-NEECDPGGCLIELTTQLSIIMGGKAIW-NNIQEVLLPWVKNLILRH-------CRGASEAA-IPRWEQDYRLQPLLGLF
YEYLEMVIQFGFVTLFVASFPLAPILALVNNVFEIRVDAWKITTQFRRIVPEKAQDIGAWQPILQGIAILAVATNAMIIAFTSDMIPRLVYYYPYGD-HT
MQGYINSSLSVFNIDDFS-NYS-KP------------YRDFRYGPGHPRQYEYTIYYWHVIAAKMAFIIVVEHIVYLTKFILSYVIPDVPYAVREQIKRE
KYLTQVVLHETNLKLVTKRRKIV-------------------------------------
>tr|H2ME71|H2ME71_ORYLA Anoctamin OS=Oryzias latipes GN=ano6 PE=3 SV=1
--------------------------------------------EFNDKPESLFFNDGIRRIDFILVYEDEDKKEF--EK--------------------
---------------------QRRKRRREYFEASLMKMGLELEATPS-VNDKLMFVKVHLPWDVLCTYAEVLHIKLPIRND-------------------
---HFYPDEKLI---EVEFFTAPFEKN----FYIKDKDLFFTPSMRSRM-CYILSKAQYEIR-----ITKLLNSGVYKAAYPLHD----KS-EAPSERYL
LYNEWANPKNFYKMQPLDLIRKYYGEKVGIYFAWLGFYTMMLAVAAVVGLGCFIYGLKSQE---S-KEVCDPDGKIVMCPQCD-LCKYWILNSTCETSQK
LSIFDNFGTLVFAVFMSIWV-LFLEFWKRYQAELEYEWDTVEFL--E-------RPEYEARC---------KNITPFT---SC--RCVRI-IGIGTVCFW
IMLILA-IVA-IVYRLAVFITFSYQRN--LE--PQMATSVTASLISFVVIMILNILYERVAIWITNF--PRTRTDYENSLTMK---FQFVNYYSSCFYIA
FVKG--VGYPGKPVKLLGEY-SEECDPGGCLMELTTQLAIIMGGKAIW-NNIQEVLLPWVKNWLFRR-------CSNVTEKV-TPRWEQDYQLQAILGLF
YEYLEMVIQFGFVTLFVASFPLAPVLALINNLFEIRVDAWKFTTQSRRIVPQKAQDIGAWQPILQGIAILAVATNAMIIAFTSDMIPRLVYYFPYSD-HT
MRGYINSSLSVFNISDSPFDLTDIA------------YRDFRYPPGHPWQYEHNIQYWHVLGAKLAFIIVVEHIVYLTKFLLSYVIPDVPYAVKERIKRE
KYLTHVILHETSLKLVTRRLKPL-------------------------------------
>tr|H2UZR1|H2UZR1_TAKRU Anoctamin (Fragment) OS=Takifugu rubripes GN=LOC101067953 PE=3 SV=1
----------------------------------------PRLAEFNDKPDSLFFNDGARKIDFILVYEDEDKKEF--EK--------------------
---------------------QRRKRRREYFEASLMKMGLELEATQS-IDDKLTFVKVHMPWDMLCTYAEVLHIKLPIQND-------------------
---HFYPNEDLI---EADYFTAPFEKD----FHIADKDSFFTPSMRSRM-YYLLSRAPYEIR-----ISKLLDSGVYKAAYPLHD----RTPDCPNERFL
LYQEWAHPKSFYKMQPLDLIRKYYGEKIGIYFAWLGFYTIMLTLAAIVGLACFIFGYKTQE---S-KEVCDPEGKIVMCPQCDRECNYWRLNSTCEASKK
LCIFDNFGTLVFAVFMSIWAVLFLEFWKRYQAQLEYEWDTVEFL--E-------RPEYEAKC---------KNVKPYT---GC--RCVRV-LGIGTVIFW
ILLILA-IVA-TVYRLAAFFAFSARRA--LE--PQMATSVTASLISFVVIMILNILYERVAIWITNF--PRTKTDYENSLTLK---FQFVNYYSSCFYIA
FFKG--VGFPGDPVYIMGKY-NEECDPGGCLIELTTQLSIIMGGKAIW-NNIQEVLLPWVKNLIFRY-------CSAT-EKI-IPRWEQDYRLQPYLGLF
YEYLEMVIQFGFVTLFVASFPLAPVLALVNNLFEIRVDAWKITTQFRRVVPEKAQDIGAWQPILQGVAILAVATNAMIIAFTSDMIPRLVYYFPYGE-HT
MEGYINSSLSVFNTRDFL-EDS-RP------------YRDFRFPPGHPRKYEFDMRYWHVIAAKMAFIIVVEHIVYLTKFVLSYVIPDVPYAVREQMKRE
KYLTQVILHETNLKLVTKRLRPV-------------------------------------
>tr|I3K105|I3K105_ORENI Anoctamin OS=Oreochromis niloticus GN=ano6 PE=3 SV=1
----------------------------------------AQEVEFNDKPDSLFFNDGVRRIDFVLAYEDEDKKEY--EK--------------------
---------------------QRRKNRRECFEDNLMKMGMELEATQ--LDEKLVFLKVHMPWDVLCTYAEVLHIKLPIQND-------------------
---HFYPDEKLI---ESEFFTAPFEKN----FCIKDKDHFFTPSMRSRM-YYILSRAPYEIR-----ITKLLDGGVYKAAYPIHD----KSPECPNERYL
LYEEWAHPKSFYKMQPLDLIRHYYGEKIGIYFAWLGFYTRMLTWAAVVGIGCFIYGYYTRD---S-KEVCDPDGKIVMCPQCD-TCQYWTLNSTCNTSKN
LCIFDNFGTLVFAVFMSVWV-LFLEFWKRYQAELEYEWDTVEFL--E-------RPEYEAKC---------KNVKPYT---AC--RCVRV-IGMTTVIFW
IMLILA-VVA-TVYRLAVFFTFSRERY--AE--PQMATSVTASLISFVVIMILNTLYERVAIWITDF--PRTKTDYENSLTLK---FQFVNYYSSCFYIA
FAKG--VGYPGKPVYLLGKY-NEECDPGGCLIELTTQLAIIMGGKAIW-NNIQEVLIPWLKNLIYRR-------CHVTTEKV-IPRWEQDYQLQPSLGLF
YEYLEMVIQFGFVTLFVASFPLAPALALLNNIIEIRVDAWKLTTQFRRAVPEKAQHIGAWQPILQGITILAVVTNAMIIAFTSDMIPRLVYYYPYGN-NT
MKGYINSSLSVFSTNDFQ-TVDDDY------------YRDYRFPPGHPKQYEYNMFYWHVIAAKMAFIIVVEHIVYFTKFILAYIIPDVPYAVKEQIKRE
KYLTQVILHETNLKLVSKRLKAT-------------------------------------
>tr|F1QNZ8|F1QNZ8_DANRE Anoctamin OS=Danio rerio GN=ano6 PE=3 SV=1
----------------------------------------VPIVDFNGNQDFLFFNDGKRRIDFVLVYEYEESKNGSNKK--------------------
---------------------RRKKRRREFFEGSLMNKGLHLEMTQS-VDEKLFFVKLHMPFDVLCANAEVLHIKLPIKND-------------------
---PFYPNEDVI---EPDYFTAPFRKD----FQLKERRELFTPTMRSRM-YYILSRAEYDIK-----ITKLLAGGIYKAAYPLHD----KSEDCPNERYL
LYSEWAHPKNFYKMQPLDLIRKYFGEKIGIYFAWLGFYTFMLSLAAAFGLGCFIYGYRSRE---S-KEVCDPDGQIVMCPQCDNNCPYWRLNTTCESSKR
LCVFDNFGTLVFAVFMSVWV-LFLEFWKRYQAKLEYKWDTVEFQ--Q-------RPEYEARC---------FSSNPYT---AC--KCMRV-CGIGTVLFW
ILLIVA-VVG-IVYRLAMFMVFSMQRSDLLE--PQMATSITASIINVIIIMILNIVYEKVAVWITDF--PRTKTEYENSLTLK---FQFVNFYSSCFYIA
FFKG--VGYPGEPVYWLGKF-NEECDPGGCLTELTTQLSIIMTGKAVW-NNIQEVLLPWLKNLMFRH-------CQVGSEKA-IPRWEQDYQLQPMLGLF
YEYLEMVIQFGFVTLFVASFPLAPLLALVNNLFEIRVDAWKFTTQFRRIVPEKAQDIGAWQPILQGVTILAVVTNTAIIAFTSDMIPRLVYYSPYVE-HT
MAGFIDSSLSVFNISHFDDKTRPRDDIKPI-------YRDYRNPPDHQNPYQFNVYYWHVIAAKLAFMIVVEHIVYFTKFMLSYLIPDVPEALNEQIKRE
RFLTRDILNNSQLTDLIKPIR---------------------------------------
>tr|G3Q658|G3Q658_GASAC Anoctamin (Fragment) OS=Gasterosteus aculeatus PE=3 SV=1
----------------------------------------------------LYFSDGKRKVDYVLVLHQRRNGSIRSHASAA-----------------
-VSHDRL-------SIVS--NHEVRLIRQEFEASLLEAGLELERD---KTYGPSFTRLHAPWPVLCREAEFLKIKVPTKTSYELKEESGFGSSMSTVWRK
MNHPFQPKVPHQEQERTKFLTHCFSRDKLHLYNITSKDTFFDNATRGRIVYEILRRTVCVRTCQTI-ISTLIAKGVYDDAFPLHDGDYKVILEEKSDRQV
LHNEWAKYSAFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQLLIPASIVGIIVFCYGVATVDSDVPSLEMCDERLNFTMCPLCDGACDFWQLSTACGTARA
SHLFDNPATVFFAIFMSLWVALFLEHWKRRQISLSFSWDLTGIEEDE----EHPRPKYETILLEKLMQEIP--GRAAIEKLTWKDRLPGYFINVSSVLFM
FGLTFSAVFGVIIYRITVSALMAMSPDPDTKSNVRVTVTATAVIINLVVILILDEIYGAVALWLTELEIPKTETHFEERLILKAFLLKFMNAYAPIFYVA
FFKG-FAGRPGSYVYVFNHYRMEECAPGGCLIELCIQLSIIMLGKQLIQNNIFEIGIPKLKKLVRALKDKGTA-KME-E-ERPPKQWNLDYALAPFDGLT
PEYMEMIIQFGFVSLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILSGMGKFSVIINAFVISFTSDFIPRLVYQYMFSQTGT
MHGFIDHTLSYFNVSNFKPGTAPQNLEQ--GSITVCRYKDYREPPWSPDAYTFSKQYWCVLAARLAFVILFQNLVMFLSLIVAWGIPDVPKTIVEQFKRE
KKLLVDVFLREEKEKFQLIQSLF-------------------------------------
>tr|G1KQX7|G1KQX7_ANOCA Uncharacterized protein (Fragment) OS=Anolis carolinensis GN=ANO5 PE=4 SV=2
----------------------------------------LRIDKRHQSKDSIFFRDGVRRIDFILAYVDDPKIEGEKKV--------------------
---------------------E--------FENNLAKAGLELETEDKKENGKTYFVKIHAPWEVLTTYAEVLNIKMPIKND-------------------
---PFRLPEIVM---EPDYFTAPFSKE----YLIDDENTFFSPSVRNRI-FYILTRCPYGTEE----IKRLINNGTYSAAYPLHD----KAPKCENERYT
LYREWARFPRFFKEQPLDLIRKYYGERIGIYFAWLGFYTEMLFFAAVVGSICFLYGAFTMN---N-REICEPSGEIIMCPLCDIKCDYWRLNSTCETSEY
SHLFDNVATLFFAIFMGIWV-LFLEFWKRRQARLEYEWDLVDFEEEQ-------RPEYEAKC---------KNLEPLT-------QALRF-ISGTTVLFW
ISLIIA-MIA-IVYRLAVYAAFASIENTQLQ--PQLATSVTASFLNFVIIMILNFLYERIAIWITDM--PRTHFEYENRLTMK---FQFVNYYSSCFYVA
FFKG--VGYPGSYTYMFDRW-NEECDPAGCLIELTTQLTIIMAGKQIW-GNIQEAFVPWIWNWWGRRK-------RNNPENL-YGRWEQDHDLQNFLGLF
YEYLEMVIQFGFITLFVASFPLAPLLALMNNILEIRVDSWKLTTQFRRPVAAKAHSIGIWQEILNGMAILSVVTNAFIVAFTSDMIPRLVYYYAYST-SP
MSGYINDSLSVFRISDFLEKNRPE--ENPG--FSTCRYRDYRYPPDHEKQYTHTMQFWHILAAKMAFIIIMEHVVFVVKFFVAWMIPDVPAEVKAKIKRE
KYLTQKILHEYELYKLKQKLCEG-------------------------------------
>tr|A0A023EW84|A0A023EW84_AEDAL Anoctamin (Fragment) OS=Aedes albopictus PE=2 SV=1
----------------------------------------EE-LHKDCHGTWNRFQDGKRVVDFVLAYNGQDQSE-------------------------
----------------------DMARKRATFQQNLQAEGLEIEPEC---SQRIHFIKIHVPQEVLSRYCEIMRMQMPTALP----D-NI----DFSV---
-SGFVIIDRDKFR--KEYQLQHEYSRDKSYLFDD-GQPDFFTPSIRIAV-HFILERTYFNVGE----LRKLLNDGVYLDAYPLHD------E-VECQRTL
LLQEWASVIRWIKHQPLDHIKEYFGVKVAMYFAWLGFYTHMLIWASIVGLLCFFYGLLTF-DNRISQDICND-NSTIMCPQC-AKCDYWRLNDTCMTSQL
AHIFDNNFTIVFAVFMSIWA-LYLEMWKRYSSAIQHRWGITDYCSLA----EPPRPQYLSRLKDSKK----FNQEPF-----WTKKLPSFLYSYSVIFLF
ITLAIA-VFG-IIYRMSLMTSRNIYGDPDAV--KLLLLPATAAIINLIVSTILNFAYDYVAVYMTDIEYRRTQSEYNESLNLK---FQFINYYSSIFYIA
FVKG--PGYPAKYN------RQEECSPGGCLMELCIQLAIIMIGKQII-SLILEILIPFLLQKFREFRSVLGIE--NGEKLICCNQWTKDFTLISWRSLF
EEYLKMIIQYGFITIFVVAFPLGPLFALLNNVFETRLDAKKFLLYYKRAVPQRVRSIGMWYNVMHVVGKVAVISSAFIIAFSSNFIPRLVYMYVVSS--T
DRGYLNHTLAYFNVSDFEPG----------EN-TECRYHEYRNPPG-VRAYKRPLIYWHILAIRLAFVVIYQNVVSFVQIVVAWAIPDTPGRLQDQIKRE
QYLTNEFIIQQEKLKTRERKCGR-------------------------------------
>tr|W5JDY9|W5JDY9_ANODA Anoctamin OS=Anopheles darlingi GN=AND_007342 PE=3 SV=1
----------------------------------------RR-LHKDCRGTWKYFQDQKRVVDYVLAYNGEEEEN-------------------------
---------------------PIAHAKRMVYQRNLEQEGLQIETES---CQRIHFVKIHVPDQVLSHYCEIMKMQMPMKLA----D-KI----DFSI---
-QSFVIIDRSIFA--PEYRLLYEYSRDKPYLFND-REPNFFTPSLRIAV-NFILERAYFSNNL----IRRLVEDQVYLDAYPLHD--------SSCQRAL
LLQEWASVRKWIKHQPLDHIKEYFGVKIAMYFAWLGFYTHMLIPASVVGLICFFYGLLTY-ENRISQEICND-NNTIMCPQC-EYCDYWYLNSTCTISKL
AHIFDNEMTIVFSIFMSIWA-LYLEMWKRYSSKIQHRWGITEYCSLA----EPPRPQYLARLKNIKK----FNQEPF-----WTKKFPSFVYSYSVIFLF
ILLTIA-VFG-VVYRMSLMTSRNIYGDHGSV--KLIIFPATTAVINLLVSTILTYAYHYVAVYMTNVEYRRTQTEYNESLNLK---FEFVNYYSSIFYIA
FVKG--PGYPAKYN------RQEECSPGGCLMELCIQLAIIMVGKQAI-GAVTEIVIPWAIQKFKEFRSVLGIE--SDERLICCNQWTKDFNLINWRSLF
NEYLKMVIQYGFITIFVVAFPLGPFFALLNNVVETRLDAKKFLLYYKRAVPQRVRDLGIWYNIMHVVGKVAVISSAFIIAFSSNFIPRLMYMHVVNP--T
DEGFVNHTLAYFNVANFEDH----------TN-TTCRYSEYRNPPDH-SPYKRPSIYWHILAIRLAFVVIYQNLVSFVQIVVAWAIPDVPGRLQDQIKRE
QYLTNEYIIEQEKLKMQRGAAGG-------------------------------------
>tr|B0XDV5|B0XDV5_CULQU Anoctamin OS=Culex quinquefasciatus GN=CpipJ_CPIJ017302 PE=3 SV=1
---------------------------------------------MYSKYTWNRFQDGKRVVDFVLAFNGHLQND-------------------------
---------------------EEADRKRKIFQENLIREGLEIEPET---TQRIHFIKIHVPPEVVSRYCEHMKIMMPIVLK----E-NI----EFSI---
-GGFVIIDRDKFR--REYRLLHEYSREKCYLFDA-DAPDFFTPSIRIAV-HFILERARFGLE-----LRKLLNDQVYLDAYPLHD------E-LECQRTL
LLEEWASVIRWIKHQPLDHIKEYFGVKIAMYFAWLGFYTHMLISASIVGLLCFFYGLLTF-ENRISQEICQD-NTTVMCPTC-AKCDYWMLNDACTYSHI
SHIFDNNFTIVFAVFMSIWA-MYLELWKRYSSDIQHRWGVTDYCLLA----EPPRPQYLARLKDTKK----FNQEPF-----WTKKLPSMLYSYSIISLF
IVLALS-VFG-VIYRMSLMTTRNIYGNPDDA--KLLLFSGTTAVINLMVSTVLNYAYDYVAVYMTDIEYRRTQSEYNESLNLK---FQFINYYSSIFYIA
FIKG--PGYPAKYN------RQEECSQGGCLVELCIQLAIIMVGKQVI-ALILEIMLPFCWQKLKEFRSVLGLAKPGGEQLICCNQWTKDFNLLSWRSLF
EEYLKMIIQYGFITIFVVAFPLGPLFALLNNVFETRLDAKKFLLYYKRSVPRRVRDIGIWYNVMHVLGKIAVISSAFIIAFSSDFIPRLYYKYLLNE--T
EAGFVQHTLAVFNVSDFEEG----------TN-TQCRYQEYRNPPDHPRPYKRPLFYWHMLALRLAFVVIYQNVVSFVQIVVAWAIPDVPGRLQDQIKRE
QYLMNEYIIKQEKRLTDRRKGGG-------------------------------------
>tr|M4APW2|M4APW2_XIPMA Anoctamin OS=Xiphophorus maculatus GN=ANO1 (2 of 2) PE=3 SV=1
----------------------------------------LNPEESINCYHGLFFQDGQRRVDYILTYPVRKSGGGRSSRQSD-----------------
-HS-L-----------TE--NDHKTFRREEFEKNLKEMGLELEKDEE-MIPGLGFVKIHAPWNVLCREAELMKLKMPTKKVYEVKQSSNFMKKISSLVNK
VLEPLHPNVEDHHSKNIKHLSHSFSREKQHLFDLSDKDNFFDSKTRSSIVFEILKRTKCK-AKFSM-ITSLLGSGVYSAAYPLHDGAIEEE-AEPNDRKL
LYEEWANYSVFYKYQPIGLVRKYFGEKIGLYFAWLGLYTQMLIPASLVGVIVFLYGCATVDDNIPSMEICDPKNNITMCPLCDRVCSYWKLSTACGTARA
GHLFDNPATVFFSIFMALWAAMFMEHWKRRQMRLNYEWDLTGFEDEEEALKDHPRAEYEFRVMQKSLKKEK------VEKLTCRDRLPAYMTNIVMMLLM
IGVTFAIVFGVILYRISTKAALYMSSSPTTRSHVQLTVKTTAAIINLVVILILDEVYGAVARWLTVLEAPKTEKNFEERLIFKTFILKFVNAFTPIIYIA
FFRG-LVGRPGRYLYVFESYRMEECSDGSCLMELCIQLSITMLGKQLIQNNLFEIGIPKLKKLIRYIQSEQGAF-QEEERQKKLRRYETDHFLEPFGGLT
PEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAARAKDIGIWYDILRGVAKVAVVINAFVISFTSDFIPRMVYQYMYSPDGS
LHGFVNHTLSYFNVSHFEHGKETMDPMPYGYPIEVCRYKDYREPPWSLTPYEISKEFWAVLAVRLAFVIVFQNVVMLMNDIVDWLIPDIPKDISQQIHKE
KILLVELFMRQEQGMINILERGG-------------------------------------
>tr|I3J8B8|I3J8B8_ORENI Anoctamin OS=Oreochromis niloticus GN=ANO1 (1 of 2) PE=3 SV=1
----------------------------------------LTPEENTRSQHGLFFQDGQRRVDYVLTYSVKKSSGSHSTRQSV-----------------
-HL-L-----------TE--NDQKAFRREEFEGKLRDMGLELEKDED-KIPGVYFVKIHAPWNVLCREAEFMKLKMPTKKANKINQSNSIVEKISTLISK
ILEPLHPHVEEHQPKNIKHLSHTFSREKQHLFDLSDKDYFFDSKTRSSIVFEILKRTKCK-AKYSM-ITSLLGSGVYTAAYPLHDGEIDEE-ADPNDRKL
LYEEWANYSVFYKYQPIGLVRKYFGEKIGLYFAWLGLYTQMLIPASLVGVIVFLYGCATVDDNIPSMEICHPRNNITMCPLCDRVCSYWKLSTACGTARA
SHLFDNPATVFFSIFMALWAAMFMEHWKRRQMRLNYEWDLTGFEDEEEALKDHPRAEYEFKVMQKSLRKRQADI-FQIEKLTFQDRLPAYMTNIVMMLLM
IGVTFAIVFGVILYRISTKAALHMSSSLITRNHVQLTVKTTAAIINLVVILILDEVYGAVARWLTVLEAPKTDKSFEERLIFKTFILKFVNAFSPIIYIA
FFRG-LVGRPGSYLYVFDSYRMEECAHGGCLMELCIQLSITMLGKQLIQNNLFEIGIPKLKKLIRYIRSKQGAF-QEEERQKKLTRYETDHFLEPFGGLT
PEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAARAKDIGIWYNILRGVAKVAVIINAFVISFTSDFIPRMVYQYMYSPDGS
MHGFVNHTLSYFNVSHFQDGKEPMDPSHFGYPVVICRYKDYREPPWSNTPYELSKEFWAVLAVRLAFVIVFQNVVMLMNDIVDWLIPDIPKDISLQIHKE
KILLVELFMKEEQGKSYIIDSST-------------------------------------
>tr|G3NCR8|G3NCR8_GASAC Anoctamin OS=Gasterosteus aculeatus GN=ANO1 (1 of 2) PE=3 SV=1
----------------------------------------LTPQESSLCQHGLFFLDGQRRVDYVLSYPSKKPSSGRSGRQAT-----------------
-HL-L-----------TE--NDQKILRREEFEGKLRDMGLELEKDEE-KISGVSFVKIHAPWNILCREAELMKLKMPTKKVYEVKQLRGVVEKISSLVSK
VVEPLHPQVEEHQPKNIKHLSHTFSREKQHLFDLSDKDYFFDSKTRSSIVFEILKRTKCK-AKYSM-ITSLLGHGVYTAAYPLHDGDINEE-AVPNDRKL
LYEEWANYGVFYKYQPIGLVRKYFGEKIGLYFAWLGLYTQMLIPASLVGVIVFLYGCATVNDNIPSMEICNTMNNITMCPLCDRVCSYWELSSACATARA
SHLFDNPATVFFSIFMALWAAMFMEHWKRRQMRLNYEWDLTGFEDEEEALKDHPRAEYELRVMQKSTSKDQ--C-STIKKLTCQDRLPAYMTNLVMMLLM
IGVTFAIVFGVILYRISTKAALYMSANPVTRSNAQLTVKTTAAIINLVVILILDEVYGAVARWLTVLEVPKTDKSFEERLIFKTFILKFVNAFTPIIYIA
FFRG-LVGRPGSYLYVFESYRMEECAHGGCLMELCIQLSITMLGKQLIQNNLFEIGVPKLKKLIRYIRSKQGAF-QEEERQKKLQRYETDHFLEPFAGLT
PEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAARAKDIGIWYNLLRGVANVAVIINAFVISFTSDFIPRMVYQYMYSPDGS
MHGFVNNTLSYFNVSHFQQGKEPMDPLYLGHPVQMCRYKDYRDPPWSTTPYEISKEFWAVLAVRLAFVIVFQNVVMLMSDIVDWLIPDIPKDISLQIHKE
KILLVDLFLKEEQGKAGNLE----------------------------------------
>tr|F7B4Z3|F7B4Z3_MACMU Anoctamin OS=Macaca mulatta GN=ANO1 PE=3 SV=1
----------------------------------------LSVDPDAECKYGLYFRDGRRKVDYILVYHHKRSSGSRTLVRRV-----------------
-QHS-------------D--TDDKRFRREEYEGNLLEAGLELERDED-KIHGVGFVKIHAPWNVLCREAEFLKLKMPTKKMYHINETRGLLKKINSVLQK
ITDPIQPKVAEHRPQTMKRLSYPFSREKQHLFDLSDKDSFFDSKTRSTIVYEILKRTTCTKAKYSMGITSLLANGVYAAAYPLHDGDYEGENVEFNDRKL
LYEEWACYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQMLIPASIVGIIVFLYGCATVDENIPRGPFCPPQPHVTACASWASRCPQRRLQWAEIVPLH
SSLGDN-SKTLLIVLITIFSATFMEHWKRKQMRLNYRWDLTGFEEEEKALLDHPRAEYEARVLEKSLKKEYIPAGTDKVKLTWRDRFPAYLTNLVSIIFM
IAVTFAIVLGVIIYRISMAAALAVNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVA
FFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKRQSPPDHEECVKRKQRYEVDYNLEPFAGLT
PEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGT
MHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKE
KVLMVELFMREEQDKQQLLETW--------------------------------------
>tr|G3PIG9|G3PIG9_GASAC Anoctamin OS=Gasterosteus aculeatus GN=ANO2 (1 of 2) PE=3 SV=1
----------------------------------------PLPESGIDLGPGLFFADGKRKVDYVLCYKLKKRHASRPRLSIT-----------------
-SNGSIP--------LPV--LEEKAVMREEFEAGLLDAGVQLQRDK---ANGLGFIRLHIPWPILSREAELQKIKVPVK-----KKCEL-AGLWDSIMRK
VNI-FQPDVP-DF--HFKTLKHPFIRDKLH-YDIKSTDTVFDNATRSRI-AEIISRVTCRQTC----INSLLARGVYDSAFPVHD------KDQRNDRQI
LHEEWANYGVMHKYQPVDLIRKYFGEQIGLYFAWLGVYTQLLIPPSVLGIFVFLYGIFTVDANVPSQETCDDNLNITMCPLC-GVCDYWRLSTVCSLARA
SYLFDNGVTVLFAIFMSLWA-YFLEHWKRRQMCLKHTWDLTSLEDEEDRVQEELRPEYEEVLQEKKAKM--AQRELD-----IEDHLSGYLINVSTLLLL
IFVTFS-VVG-AVYRICMLSVWSMNPDP-AK--VRMTVTTTGIILNMLVVLVLEEVYGAIAVWLTELELPKTKEEFEEKLIFK---LKSMNAFAPIFYVA
FFKG--GGRPGDYVY-----RMEECAPPGCLIELCIQLSMIMLGKQLIQNNVFEVLIPKLKKMYRTIQEEKVKKENATEEKRPKQQFDKDYALEPY-GVT
PEYMEMIIQYGFVSLFVASFPLAPAFALLNNVIEIRLDAAKFVTEIRRPDAVRCKDIGIWYNILCGISKFSVITNAFVISFTSEFVPRMVYQYMYSV-GT
MNGYTEHSLSYFNVSNFPPGSAPTTA----TGVSMCRYKDYRDPPWDTEAYTFSKQYWSVLAAKLAFVIFFQNFAMFLSMLVAWMIPDVPRSLREQLMKE
NMMLMEFLLNQDQEETLHPALQR-------------------------------------
>tr|L7M0W3|L7M0W3_9ACAR Anoctamin OS=Rhipicephalus pulchellus PE=2 SV=1
----------------------------------------DGTAAVVDESGCVYLSGSRRKVDFVLAYSPA-----------------------------
----------------------KHQAIRDIFEEELSKAGLVLEHVP--NPSGLCFVKIHAPWEVLSCFAEIMRLKMPVKWSLD-----------------
---CEPVEIRSMG---QKQFAVTFSMSKEY-FDIEPKEDFFSAAQRAQV-HFILQRKSFSRDT----IGRLLADGVYLAAYPLHE------EDSEAPRTK
LRRKWASLLAIFRYQPLDEVRRYFGVKIGLYFAWLGFYTTMLLPASLLGLGCFLYGVATLGKHRPVHEMCTGSSQLLMCPLC-NGCEYWRLRDSCTQARL
GYLSDNGATVVFSIFMSLWG-AFLELWKRYSARITYQWDLSGFDTLE----ENSRPEYLARLSRLKKR---VEGISF-----WRIRLPFGLLSVSVVLLL
VLLAVA-VVG-IVYRMSVRATLALQSEE-MS--IPLITSTTAALLNLLCILLFNMLYTRLAVYLTEMEMPRTQTEYDDSLTLK---LQFVNCYSSIFYIA
FFKG--VGRPGKYNT-----QQEECGLGGCFVELSIQLAIIMVGKQAF-SAISEMALPYAMRLWSH---M--SF-SN-NEHQPKQPWERDYLLPDMTGLF
HEYLEMILQYGFVTLFVAAFPLAPLFALLNNVLEIRLDALKLLGSYRRPVAVRVRDIGIWYRIMDSLGKLAVLTNAVLIAFTSDLVPRLYYRWKVSP-GT
LDGFVDFSLSYFDVQDYDEGVRHG---NTSLGSRYCRYADHRTPPWVENQYKRTSQYFEILVWKFAFVLLFENIIAFLMTLIRWIIPDVPKTIREKIRED
NRLTNEIIILQELRRRHVDSPPP-------------------------------------
>tr|A0A0C9R9J9|A0A0C9R9J9_9HYME Anoctamin (Fragment) OS=Fopius arisanus GN=Ano1_0 PE=3 SV=1
--------------------------------------------VPHSNTGSLFFKDEIRSIDFVIVWDEHDE-E-------------------------
---------------------LRNIEYRKIFESNLELEGLHLEQEP--EPSGLRFTKVHAPREVLRRYAEILKLRLAMKLSRE---------VNT-CFRI
FFS-FYVDQT-IF---KHQYTAVYSRDKEY-FDL--APDFFSSATHSRI-QFILDRTKFSEVN----IDRLISERAYVAAYPLHD------S-PDSIRCL
LYTHWASLSKFLNHQPLDYIKEYFGVKIGLYFAWLGFYTHMLVPASVIGLLSFIYGCISLSSNLPSEDICHGNNSIDMCPLC-KICGYWNLRETCLHSRL
TYLFDNPSTVFFAVFMSLWA-LFLELWKKYSAEITHRWDLTGLDAQE----EHPRPQYLARLSHIQKK---LNLEPF-----WSMRLPATILSFSVVLLL
IAVAMA-VIG-ILYRMSILTTLSVY-GE-IT--AILFTTATAACLNLCCIFLFNWLYVWLAEYLTEMELLRTQTEFDDSLTLK---LQFVNYYASIFYIA
FFKG--VGHPSTYNR-----RQEECGPGGCLTELCIQLSIIMIGKQAM-NSFLEMMFPLFYKWLNT-WKVRNNPKE-DTTSRKLPPWVRDYKLVEWRSLF
PEYLEMVLQYGFVTIFVAAFPLAPFFALVNNVFEMRLDAKKLLTMYRRPVSQRVRDIGIWYRILDSVAKLSVITNGFIIAFTSNFIPKIVYQLSVSE-GS
LEGFLEYSLSKFNTSDFEEDMRPQ---DVRRHVDVCRYPDFREGPGEDGKYQVTSTYWRILAARLAFVVVFENIVALVMILVRWCIPDMSPELRDRIRRE
TYITNEIIIQQEALRACGRGVD--------------------------------------
>tr|A0A022T5Y5|A0A022T5Y5_9HYME Anoctamin OS=Microplitis demolitor GN=K425_619 PE=3 SV=1
-----------------------------------------------DETLNLYFTDGIRSIDFVIVWDEHDE-E-------------------------
---------------------LRCTEFRKIFEENLELEGLQLEYES--EPSGLRFIKIHAPQEVLRRYAEILKLRLPMKLIRE---------VNS-WITN
FMK-YYVDTT-IF---KHRFTAVYSRDKEY-FDY--IPEFFTPATHSRI-QFILDRTKFTKNK----IDRLISEHAYVAAYPLHD------T-PASMRYL
LYTHWASLRKCFHYQPLDYIKEYFGVKIGLYFAWLGFYTHMLVPASIVGLICFIYGCLTLYTNQPSEDICNGNKSIYMCPLC-HICGYWDLKETCLHGRL
TYLFDNPSTVFFSIFMSLWA-LFLELWKKYSAEITHRWDLTGIDAQE----EHPRPQYLARLAHIKKK---INAEPF-----WSMRLPATILSFSVVLLL
ITVAMA-VMG-ILYRMSLLTTLSVY-GH-IT--AILFTTATAACLNLCCIFLFNWIYIWLAEYLTELELLRTQTEFDDSLTLK---LQFVNYYASIFYIA
FFKG--IGHPRTYNR-----RQEECGPGGCLTELCIQLSIIMIGKQFM-NSLLEMLFPLYYKWINT-WKVHIKSKNDKFILRKHLPWLRDFKLVEWRSLF
PEYLEMVLQYGFITIFVAAFPLAPFFALINNIFEMRLDAKKLLIMYRRPVGQRVRDIGIWYRILDSISKLSVITNAFIIAFTSNFIPKLVYQLKISD-YS
LEGFLEYSLSKFNTSDFLSEHRPL---INTEDIEICRYPDFRESPTSPNKYNFTNIYWYILAARLAFVVVFENAVALVMIFVRWCIPDISPKLADKIRRE
IYITNEIIIQHEAQRACSRSSAA-------------------------------------
>tr|C3ZNN9|C3ZNN9_BRAFL Anoctamin (Fragment) OS=Branchiostoma floridae GN=BRAFLDRAFT_235819 PE=3 SV=1
----------------------------------------------------------------------------------------------------
---------------------DQKARRRREFEKNLIEAGLDLERDDE-KDHGMCFVRLHAPWKVLSQYAEILKIKMPTKKIYEIKERAGIKAKAYALWRK
TIRPLQPSAQAKQVDPYKHISYTFSRDKEHMFHIESRETFFKPSTRSLVVHEILKRTRYSQKDYAI-ITNLIAQGVYTAAYPLHEGEFEGDNIPPNPRQM
LFDEWGSYSKFVKFQPLNLIRNYFGEKIGMYFAWLGLYTKLLIPSSFVGLIVFLYGVFTMDDNVPSDEVCEA-YNITMCPLCDRECKYWRLSDSCKSARF
SHLFDNEVTVFFSIFMSLWATWFLENWKRKQMELNYAWDLSGFEEEE----EQPRPEYEARLVKHRIEQSDP----------KKQTLFAVGVSSVTILTM
FTVTLAAVFAVIMYRLSVASALAIYPNS------GQIVSGTAVTLNLIVILILDEIYGSVAAFLTQLECPRTETEYEDKLIFKLFLLKFVNSYASIFYVA
FFKG-FMGRPGQYIYAAPGLRMEECGPGGCLYELCIQLSIIMAGKQLIQNNVMEIGMPKLKKFLRECTCFGLCKA--DKAGPRDTRWEEDLVLEPFSGLS
PEYLEMIIQFGFVTIFVASFPLAPLLALVNNVLEIRLDARKFVQELRRPMAERAKDIGIWYNILKGITKISVIVNAFVIAITSNFIPRTVYQYMYSPDGS
LHGFIDWSLSTFNVSDFEPGSEPRDNRSLGEVVQFCRYRDFRDAPWEAEPYKYNLAYWHIFAARLGFVICFQNFIIFLRDFIGYIIPDVPKELDEQIKKE
NKIMMDALIHEENVRQGEVDVDM-------------------------------------
>tr|K9IUD0|K9IUD0_DESRO Anoctamin (Fragment) OS=Desmodus rotundus PE=2 SV=1
----------------------------------------PEFEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKENSKKG--------------------
---------------------EKQRRKRQAYESNLIHDGLQLEATRS-LDDRLVFVKVHAPWEVLCTYAEIMHIKLPLKSD-------------------
---VLQVDESII---EQEFFTAPFEKN----FYIHDRDTFFNPATRSRI-YFILSRIKYQVR-----INRLVNSGIYKAAFPLHD----PSSSCPNERYL
LYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGFMNRN---C-KEVCDPDGKIIMCPQCN-ICPFWELNITCASSQK
LCIFDSFGTLVFAVFMGLWV-LFLEFWKRRQAELEYEWDTVE-L--Q-------RPEYEARC---------INEEPFT---TW--KCIRV-LCTSAVLFW
ILLIIA-VIG-IVYRVSVFFTLSKERPSETD--PHLATSITASLINFVIIMILNIIYEKVAIMITDF--PRTQTDYENSLTMK---FQFVNYYSSCFYIA
FFKG--VGHPGDLVYWLGKY-NEECDPGGCLLELTTQLTIIMGGKAIW-NNIQEVLLPWVKNLFG-----RY--CVSGSEKI-TPRWEQDYHLQLMLGLF
YEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKMTTQYRRMVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYPPYGT-YT
MEGYINNSLSIFKVADFQNRSLENPY-----------YRDFRNPPGHPQEYKHNIYYWHVIAAKLAFIIVMEHIIYSVKFFISYAIPDVSKSTQSKIKRE
KYLTQKLLHENHLKDMTKNMGVL-------------------------------------
>tr|L5MF79|L5MF79_MYODS Anoctamin OS=Myotis davidii GN=MDA_GLEAN10022528 PE=3 SV=1
----------------------------------------SYQEEFNGKPNSLYFNDGQRRIDFVLVYEDESRKENNKKG--------------------
---------------------EKQRRKRRAYESNLIHDGLQLEATRS-LDDKLVFVKIHAPWEVLCTYAELMHIKLPLKND-------------------
---VLQVDESII---EQEFFTAPFERS----FYIRDKDTFFNPATRSRI-YFILSRIKYQVS-----INKLVSSGIYKAAFPLHD----PSFTCPNERYL
LYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAIVGVACFLYGYLNRN---C-KEVCDPDGTIIMCPQCDRLCPFWKLNITCESSQK
LCIFDSFGTLVFAVFMGVWV-LFLEFWKRRQAELEYEWDTVE-L--Q-------RPEYEARC---------INEEPFT---TW--KCIRG-LCASAVLFW
ILLIIA-VIG-IVYRLSVFIVFSAKPKNLTD--PQTATSITASLISFVIIMILNTIYEKVAIMITNF--KYFTLCST---PNK----VEGNLLQCC--DA
NMPG--LGKLFSNPYWRE----EACSRGQCLVSVF--LKIALGES------HVQSRWIWIKNLIG-----RY--RVSGSEMV-TPRWEQDYHLQLMLGLF
YEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKMTTQYRRMVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYPPYGD-YT
MEGYINNTLSIFKIADFKNRSKGNPY----------QYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFIIVMEHVIYSVKFFLSYAIPDVSKRTRSKIKRE
KYLTQKLLHENHLKDMTKNMGVI-------------------------------------
>tr|K7IMU6|K7IMU6_NASVI Anoctamin OS=Nasonia vitripennis GN=LOC100124067 PE=3 SV=1
----------------------------------------NYPSQTETNVVNESQNNSAEGVDFVLAYVDNGNSV-------------------------
------------------------AQKREAFERSLLDQGLHLEYEQN---RQLCFVKIYASEEVLCRFCEIMKLRMPI-------N--I-----------
-LFFAQLDPTKFP--TEYKLAAEYSRDKDYLFDT-KDKNFFPTHIRVMV-DFILER-----------IQRLLAAGVYSAAYPLHD--------G-STRAL
LYEEWGDTKKWVKLQPLDTIREYFGINFAMYFAWLGFYTYMLIPASIAGLLCFFYGLIGM-SNQLAEDACGTWKETIMCPQC-KTCDFWRLSETCLLTRV
TYLFDNPAMVYFAAFMSVWA-FYLELWKRRAAELSYRWGVVGWDRTA----DHSRPQYLHALANAKL----LNKESF-----WKVRVPATFFSFSVVLLL
TALALA-VFA-VLYRMASITSTSLFGREVSA--KTFAIPAIAAGINLVCILVLNYIYDWLAVYLTEMELLRTQAEFDDSLTLK---FQFINYYASIFYVA
FLKG--VGYPKKYN------RQEECAPGGCLMELSIQLVIIMVGKQAV-YTVMEMFLPILYKYWALFRIHTGLK------IVPRSQWIRDLKLLDWRGLY
DEYLEMVIQFGFITLFVVAFPLAPFFALANNIFEMRLDATKFLRHYRRPVPRRARDIGIWGRILDALARISVTTNGFIIAFSSTYIPRLVYMTVVSP--T
DIGFLNHSLALFDTKDFANG----------EN-TTCRYAEYRNPPDHFLPYKRPSIYWHILAARLAFVVVFQNAVGLFTMAVQWCLSDKPRKLRDQIKRE
TFLTEELIIKSEAERAKSKLTDD-------------------------------------
>tr|A0A0C9R3F4|A0A0C9R3F4_9HYME Anoctamin OS=Fopius arisanus GN=Ano5_4 PE=3 SV=1
----------------------------------------NLPFPMYS-MKDSESESQRQQIDFVLAYMDNGNLT-------------------------
------------------------ALRREEFEKELRDQGLELEYEQN---RQLVFIKIHAPKEVLCRFCEIMKLKMPI-------E--L-----------
-IFCAQLDPSKFP--REAVLLAEFSRDKDYLFDL-ADDNFFLPNVRAMI-DFILER-----------IQRLVVNGVYSAAYPLHD--------G-TTRAL
LYNEWASTRKWVKLQPLDTIQEYFGVNVALYFAWLGFYTYMLIPASIAGLLCFFYGLITL-SNEIGKDACSPWDTIIMCPQC-RNCDYWRLNTTCILTKM
TLLFDTPATVVFAVFMSFWS-LYLELWRRKSEQLSYHWGLVGWDQGA----EHPRPQYLSMIQKAGLLN--LNTESF-----WSVRVPATMLSFSVVILL
VLVAVA-VFA-VLYRMSMITSNSLFGKEMSN--KTFALPSVAAAINLACILVLNYFYDWLAVYLTEMEMLRTQPEFDDSLTLK---FQFVNYYASIFYVA
FLKG--PGYPKKYN------RQEECAPGGCLMELSIQLAIIMVGKQAV-ATALEMILPILFKWWALFRIHTGLK------IPSRSQWIRDFKLLDWRGLY
DEYLEMVIQFGFITIFVVAFPLAPLFALANNVLEMRLDATKFLRHYRRPVPRRAKDIGIWKQILDALARISVTTNAFIIAFSSNLIPRLVYMKAVSP--S
DVGFLNHSLAYFNTRDFQEN----------GN-SECRYPEYRNPPDHPLPYKRPSVYWRILAARLIFVVVFQSVVGLFTMSVQWCLSGVPRKLRDRIKRE
AYLTEEIIIKREAERARERARLF-------------------------------------
>tr|M3XM57|M3XM57_MUSPF Anoctamin OS=Mustela putorius furo GN=ANO7 PE=3 SV=1
--------------------------------------------HQEAAGR--MGSPSKPRVDFVLVWEEDLKLGEQQDSTI------------------
---------------------DTHAAWRETFLENLRAAGLCVDQ----GPGTVHYILLSAPWAVLCYYAEDLRLKLPLQ---------------------
---WL-----GIP--PPEYYSCQFKLSKLSRFLGDNQDTFFTSTKRHQI-FAILAKTP---------IDQLLAEGVFTAAFPLHDPLEG--ASGLTQRQI
LFQYWARWHKWYKCQPLDHVRSYFGEKVALYFAWLGFYTGWLLPAAAVGTLVFLVGCFMVFSDVPTQELCSSADNFEMCPLC--DCPFWLLSSSCSLVQA
SRLFDHGGTVFFSMFMALWA-LLLEHWKRMSATLAYRWGCSDYEDIE----ERPRPQFAASAPM-------LNDEPE------RSRLRRVLAGSVVVVMM
VAVVIM-LVS-ILYRAIMAILMSRL--NTLA--ASRIASFTGSVVNLVFILILSKIYMALAHILTRWEMHRTQTKFEDAFTLK---FQFVNFYSSPIYIA
FFKG--VGYPGNYH------RNEE-AAGGCLIELAQELLVIMVGKQII-NNVQEILVPKLQSWWQKFRLRSKKR---R-EAAGQEPWEADYELLPC-GLF
QEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARKFVCQHRRPVAERAQDIGIWSHILAGIAHLAVVSNAFLLAFTSDFLPRAYYRGTRA----
LHGFVNFTLASA-----PPAFAAAH-------NRTCRYQAFREDDGQ-----YSPTYWNLLAIRLAFVIVFEHVVFSISRVLDLLIPDIPESVEVKVKRE
YYLAKQALAENEALSGTNGAKDT-------------------------------------
>tr|A0A096NXV2|A0A096NXV2_PAPAN Anoctamin OS=Papio anubis GN=ANO7 PE=3 SV=1
--------------------------------------------QQVAACRAGAGSPAKPRIDFVLVWEEDLKLDWQQNSAS------------------
---------------------DTHRTWRETFLDNLRAAGLHVDQ----GNTTVHYALLSASWAVLCYYAEDLRLKLPLQ---------------------
---WL-----GIP--PPEYYSCQFRVNKLPRFLGDNQDTFFTSTKRHQI-FEILAKTP---------IHQLLAEGVLSAAFPLHDPPEG--APHLNQRQV
LYQYWARWGKWYKYQPLDHVRRYFGEKVALYFAWLGFYTGWLLPAAVVGTLVFLVGCFLVFSDIPTQELCGSKDSFEMCPLC--DCPFWLLSSACALAQA
GRLFDHGGTVFFSLFMALWA-LLLEYWKRKSATLAYRWDCSDYEDIE----ERPRPQFAASAPT-------PNDEPE------RSRARRMLAGSVVIVMM
VAVVVM-LVS-ILYRAIMAIVVSRS--NTLA--ASRIASLTGSVVNLIFILILSKIYVSLALVLTRWEMHRTQTKFEDAFTLK---FQFVNFYSSPIYIA
FFKG--VGYPGNYH------RNEE-AAGGCLIELAQELLVIMVGKQVI-NNMQEVLIPKLKGWWQKFRLCSKKR---S-PGASQERWEEDYELVPC-GLF
DEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARKFVCEYRRPVAERAQDIGIWFHILAGITHLAVTSNAFLLAFSSDFLPRTYYQWTRA----
LRGFVNFTLARA-----PPSFSAAH-------NRTCRYRAFRDDDGH-----YSQTYWNLLAIRLAFVIVFEHVVFSIGRLLDLLVPDIPESVEIKVKRE
YYLAKQALAENEALFGTNGAKDE-------------------------------------
>tr|G1P567|G1P567_MYOLU Anoctamin OS=Myotis lucifugus GN=ANO7 PE=3 SV=1
--------------------------------------------HQAATCR--VGNPAKPQIDFVLVWEEDLRLGQQQDSAT------------------
---------------------DTHRAWRETFLDNLRVAGLHVDQ----EDSAVHYILLSAPWAVLCYYAEDLRLKLPLQ---------------------
---WL-----GIP--PPECYSCQFKVSKLSRFLRDDQDTFFTCTNRHQI-FEILAKTL---------IDQLLSQGVFKAAFPLHEPPEG--APGLNQRQV
LFQYWARWRKWHRYQPLDHVRRYFGEKVALYFAWLGFYTGWLLPAAVVGTLVFLVGCFMVFSDTPTQELCSSADSFQMCPLC--NCPFWLLSSACALVQA
GRLFDHGGTVFFSVFMALWA-LLLEYWKRKSATLAYRWGCFDYEDIE----ERPRPQFAASAPT-------LNEEPK------RSRMRRVLAGSVLVLMM
VAVVVM-LVS-ILYRAIMAILVSRS--NTLA--ASRIASLTGSVVNLVFILVLSKIYVALAHILTRWEMHRTQTRFEDAFTLK---FQFVNFYSSPIYIG
FFKG--VGYPGSYH------RNEE-AAGGCLIELAQELLVIMVGKQII-NNVQEILVPSPSPVPTW----KRGG---S-AAASQTPWEADYELLPC-GLF
DEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARKFVCERRRPVAERAQDVGIWFPILAGITHLAVISNALLLAFSSDSCRGTYYRWTRA----
LRGFVNFFLQKT-----QDPH-TES-------HISCRYRAFREDDGH-----YSGTYWNLLAIRLAFVIVFEHVVFSIGRILDLLVPDIPESVQIKVKRE
YYLAKQALAENEALLGTNGAKDD-------------------------------------
>tr|A0A0F7ZEN0|A0A0F7ZEN0_CROAD Anoctamin OS=Crotalus adamanteus PE=2 SV=1
----------------------------------------QKNKGCLVNSTANFFSDEKTR-DFILVWESDCQNPEGQNEEKG-----------------
-N-------------------EMHKEWREKFLHKLQMKGISIEK----TKKVVHYILLSAPWSVLCYYAEDLRLRVPLQ---------------------
---KL-----GIP--PLDNYTCHFKANKLRWFRGDDHETFFSSTQRHRI-YEILSTIS---------IERLLNEEVFTAAFPLHDLSEE--TSLLNQRQI
LFHYWAKWSKWKKYQPLNHIRRYFGEKIALYFAWLGFYTAWLLPAAVVGTLVFIIGIFLMFHDIPTQEICSSGDKYKMCPLC--VCPYWNLSSVCPMFQA
GRLFDHGGTVFFSIFMSLWA-TFLEYWKRMNATLTYRWDCSDFEDIE----ERPRPQFAALAPM-------VNEEPK------RTRFNRIITGSMVIIIM
IAVVII-LIS-ILYRAIISVIVSRS--NVLV--ASRIASLTGSVVNLLFILLLSKIYIALALFLTKWEMHRTQTTFEDAFTFK---FEFINFYSSPIYIA
FFKG--VGYPGHYD------RNED-APGGCLIELAQELLVIMVGKQVI-NNIQEILIPKMKTWWHKQD-LSESN-----DNFMKQLWESDYKLLPY-GLF
AEYLEMVLQFGFITIFVAACPLAPLFALLNNWAEIRLDAQKFVCEYRRPVAERAQGIGIWFHILEVITHFAVISNAFLIAFTSDFLPRLYYQYTRA----
LQGYIDFTLAYA-----PKSFDLNN-------NATCRYRAYREQNGR-----YSLPYWNLLAIRLGFIIVFEHVVFFIARMIDMMVPDIPEAVAIKVKRE
QYLAKQALAENKALIEVIDVVNP-------------------------------------
>tr|F6SK27|F6SK27_CALJA Anoctamin (Fragment) OS=Callithrix jacchus GN=ANO7 PE=3 SV=1
--------------------------------------------QQVAGCG--AGSPAKPRIDFVLVWEEDLKPDRPQDSAA------------------
---------------------DVHRTWRETFLDHLRAAGLRVDQ----GDSAVHYALLSASWAALCYYAEDLRLKLPLQ---------------------
---WL-----GIP--PPEYYSCRFRVSKLPRFLGDNQDTFFTSTKRHQI-FEILAKTP---------IHQLLAEGVFSAAFPLHDPPEG--APRLNQRQV
LFRHWARWGKWSKYQPLDHVRRYFGEKVALYFAWLGFYTGWLLPAAVVGTLVFLVGCFLVFSDIPTQELCGSQDSFEMCPLC--DCPFWLLSSACALAQA
GRLFDHGGTVFFSLFMALWA-LFLEYWKRKSATLAYRWDCSDYEDIE----ERPRPQFAASAPM-------PNDEPE------RSRARRMLAGSVVIVVM
VAVVVM-LVS-ILYRTIMAILVSRS--NTLT--ASRIASLTGSVVNLIFIVILSKIYVTLAHVLTRWGRVAHGRGTC--FSFS---FVFFPLPSSPLSSF
LRTN--VGHPGNYH------RSEE-AAGGCLIELAQELLVIMVGKQVI-NNMQEVLIPKLKGWWQKFRLRSK-R---S-SGAGREPWEADYELVPC-GLF
DEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARKFVCEYRRPVAERAQDIGIWFPVLTAITHLAVTSNAFLLAFSSDFLPRAYYQWTRA----
LRGFVNFTLARA-----PPHFTAAH-------NLTCRYRAFRDDHGH-----YSQTYWNLLAIRLAFVIVFEHVVFSIGRVLDLLVPDIPESVQIKVKRE
YYLAKQALAENEALFGTNGAKDE-------------------------------------
>tr|T1PLD3|T1PLD3_MUSDO Anoctamin OS=Musca domestica PE=2 SV=1
----------------------------------------NDFYMKCEKNPSLFFDDGVRSIDFVLVYKINPQ-T-------------------------
---------------------DQHEEKRHIFEMNLLSEGLEIERAC--EKEQIYFVKVHAPLEVLRRYAEILKLRMPMKIPSS---------LKG-LIKF
FMR-IYVDER-NF---AQRFTAIYSRDKEY-FDI--QDNFFTPAVRSRI-QFILDRQRFTPKS----IERMVASNIYCAAYPLHD------E-KNTMRHT
LYTHWASVRKWYRYQPLDYIKEYFGVKIGLYFAWLGFYTYMLLLASVVGVFCFIYSWSTLKDFEPVKEICGGKKNITMCPLC--WCDFWDLKETCFYAKI
SYLIDNPSTVFFAVFMSFWA-LFLELWKRYSAEITHRWDLTGFDVHE----EHPRPQYLAKLQHLPHT---TDREPF-----WRMKLPAAVFSFSMVLLL
VALTLV-VLA-VVYRMATMASLMLRKTN-NT--AIVLATSSAAFLNLCMLYVLNYVYNRLAEYLTELEMWRTQTQFDDSLTLK---LQFVNYYASIFYVA
FYKG--VGRPGAYTL-----RQEECSSGGCLTELCIQLAIIMIGKQAF-NSILEVIMPMIWRKIGA-IRVGLSKKEHDKHK-DTERWVRDLKLLDWRSLF
PEYLEMVLQYGFVTIFVAAFPLAPLFALLNNILEMRLDAKKLLTHHRRPVSQRVRDIGVWYRILDCIGKLSVITNGFIIAFTSELIPQWVYRH-YSP-SS
LEGYLDFSLSKFNTSDSNQTRSL-----SADNLTTCLYADFREPPTSEKRYHFSNIFYLVLACRLCFVVVFENFVALVMIIVRWCIPDMSVGLRDQIRRE
AYITNEIIIEQETRRARTERAKG-------------------------------------
>tr|H3CVI8|H3CVI8_TETNG Anoctamin OS=Tetraodon nigroviridis PE=3 SV=1
----------------------------------------LQTDKLQTNRDTVFFRDGVRRVDFVLSYVDDKDGE--KKQ--------------------
-------------------------ERRKEFEANLEKAGLELETEDKSKDQITYFLKIHAPWDILATYAEVLKIKVPFKSD-------------------
---PLRLPEHIM---QPDYFTYPFNKQ----FLISDKDTFFPPSTRSRI-FYILGRCPYYNEG----IKRLLSNGTYAAAFPLHD----RAAECESERYN
LYKNWARFLCFYKEQPLNLIRKYYGEKIGIYFAWLGFYTEMLFFAALMGVICFTYGLLSYD---N-KEICDPDGSIVMCPLCDKKCPFWKLNSTCLSSWQ
SHLFDNEGTVFFAIFMGIWV-LFLELWKRRQARLEYEWDLVDFEEEQ-------RPEFEIQC---------LNMEPVT-------KCARF-LSAATVIFW
ISLIVA-IIG-IAYRLAVHAAFASIKDPMIQ--PQLATSATASCINFVIIMILNFFYERVAIWITDM--PKTHLEYENKLTVK---FQFVNYYSSCFYVA
FFKG--VGYPGDYTYMFGNR-NEECDPGGCLIELTTQLVIVMTGKQMC-GNI--ALLPVMRNWWSGRK-------RHHPENH-YSRWEQDHVLQNFLGLF
YEYLEMVVQFGFITLFVASFPLAPLLALFNNILEIRVDAWKFTTSFRRPRGLGPRTSAPWLEGSTAVAVLSVVTNAFIMAFTSDMIPRMVYLYAYSN-SN
MIGYVNNSLSVYNISHIPERSMPE--EHEDTT-TTCRYRDYRYPPGHQREYTHTMHFWHILAAKM-FIIIMEHVVFMVKFFVAWLIPDVPSDVKARIKRE
RYLVQEHLHNYEVERLKMQLSAS-------------------------------------
>tr|A0A0P7TXW7|A0A0P7TXW7_9TELE Anoctamin-5-like OS=Scleropages formosus GN=Z043_123144 PE=4 SV=1
------------------------------------------------------------------MTKVAASLL--CQP--------------------
-------------------------ERRKEFEANLLKVGLQLETEDKSDDGKTYFLKIHTPWEVLATYADVLKIKVPFKND-------------------
---PFRLPETVM---EPDYFTSPFDKN----FLIDNKETFFPPSTRNRI-YYILARCPYYKEE----IKRLLNNGTYTAAFPLHD----PSSNCESERYN
LYKYWARFFRFYKEQPLNLIRKYYGEKIGIYFAWLGFYTEMLTYAAVVGLICFIYGLFTYD---N-QEICNPEGQIVMCPLCDKKCGYWKLNSTCESSWQ
SNLFDNVGTVFFAIFMGIWV-LFLEFWKRRQARLEYEWDLVDFEEEQ-------RPEYETKC---------LNMENRS-----AAFIVKL-LCWTTVVLW
MALIIA-MIG-IAYRLAVYAAFSSIKENSLQ--PQLATSVTASCINFVIIMVLNFLYERVAIWITDMERPKTHLEYENKLTMK---FQFVNYYSSCFYVA
FFKG--VGYPGKYTYMFGGQ-NEECDPGGCLIELTTQLVIVMAGKQVW-GNIQEALVPWLWNWWGSRK-------RNHPESL-YSRWEQDHDLQNFLGLF
YEYLEMVIQFGFITLFVASFPLAPLLALLNNIIEVRVDAWKFTTQFRRPVAAKAHSIGAWEEILNGVAILSVVTNAFIVAFTSDMIPRLVYYYAYHP-PT
MEGYINNSLSIYEISQFPEHNRPDQSENPVTIITTCRYRDYRYPPGHKREYSHSMQFWHILAAKLAFIIIMEHVVFVVKFFVAWMIPDVPSEVKARIKRE
CYLIQEYLHNYEVEKLKLQLSQS-------------------------------------
>tr|A0A093Q9X7|A0A093Q9X7_9PASS Anoctamin (Fragment) OS=Manacus vitellinus GN=N305_03252 PE=3 SV=1
----------------------------------------AEWVDFDDKPDSLFFSDGQRRIDFVLVYEDESKKITHKRS--------------------
---------------------NH-KRKRQVYESNLINNGLQLEATRS-LDEKLIFVKVHAPWEVLCTYAEVMHIKLPLQND-------------------
---FFKVDENII---EQEFFTAPFQKE----FYIHDKDTFFNPATRSRI-HFILSRVEYATK-----INKLLDTGIYKAAFPLHD----LSPNCPNERYL
LYREWAHPKNIFKLQPLDFIRKYYGEKIGIYFAWLGFYTNMLTVAAVVGVGCFLYGCLTKD---C-QEVCDPNGNIIMCPQCDKVCTYWNLTITCESSKK
LCIFDSFGTLVFAVFMGIWV-LFLEFWKRRQAELEYEWDTVEYL--E-------RPEYEARC---------MNQEPYT---AC--KCIRM-FCTSAIFFW
ILLIIA-VIG-IVYRLSVFLVFSATSQHL----PQTATSVTASVISFVVIMILNIIYEKVAILITDF--PRTQTDYENSLTTK---FQFVNYYSSCFYIA
FFKG--VGHPGNPVYWLGKY-NEECDPGGCLLELTTQLAIIVGGKAIW-NNIQEVLLPLVKNLIGRY-------SAARSEKV-VPRWEEDYHLQPILGLF
YEYLEMVIQFGFVTLFVASFPLAPLLALINNMLEIRLDAWKLTTQFRRMVPQKAQDIGAWQPILQGIAILAVVTNAMIIAFTSDMIPRLVYYPPYGS-HT
MKGYINSTLSIFNISDFKNASK--PFS-P----NKHLYRDLRYPPGHQHQYEHNIYYWHVIAAKLAFIIVMEHVIYFVKFIISYAIPDVSQKTKSKVKRE
KYLTQKLLHENDLKVVKKNMGKI-------------------------------------
>tr|B3RRJ5|B3RRJ5_TRIAD Anoctamin OS=Trichoplax adhaerens GN=TRIADDRAFT_54261 PE=3 SV=1
----------------------------------------SGVHTKEKKSNSVYFNDGERRIDWVLTYKISSDA--------------------------
---------------------HKNSERRKAFLDSLRDLAKVQLEEQ--VDKVTNYIKIHAPWTTLLEYAEIMRFNMPIKSA------------PEPTCQT
CPS-FELDSPYL---YNPHYTCAFKNSAI--FLIEDRDTFFTSAQRSAV-DYILKRVDYKEND----AYRLISKGAFEKSFPLHD------HAPENDRQL
LRQEWARPGRWYKFQPLDLVRKYFGEKIGIYFAWLGFYTGMLIPASILGVLCFLYGLFTMGSDKVSSEICSYNKQFYMCPLC-ELCPYWELRTTCNYAKA
S--------------------LFLEFWKRRQARIAFEWDLLDYEAEE----EPLRAQYEAKCAEEGSY---VNEETP-----TK-RLPRYFLGDISIVFM
ICLVIA-VFA-IIYRLGITYLLLRTN-I-IS--ASIFTSITAAAINLVVIMLLGVVYKILAYKLTDWERYRTQSEYDRAFTVK---FQFVNYYSSLFYIA
FFKG--SGSPNNYNR-----RQQQCSSGGCLVELCIQLAIIMVGKQAW-NNILEFILPKIKNWIARRNIDKED----DGSEKDIPLMEEDEDLQELQGLF
FEYLEMVIQFGFITLFVAAFPLAPFFALLNNVIEIRLDAYKFITQLQRPLAAQAPNIGAWYGILDSISKMAVITNAFVIAVTSDFIPRMVYEYGNVS-GT
LDGYVNFSLSYFNVTDFPSSEIPKANLSGQYTSTFCRYSGY----QTEYPYSYNLNYWRIMTVRLAFVVVFEHLIFFIKFAIGYAIPDIPKSLRLTIKRE
EYLAKQALEDDKLVRNNSNA----------------------------------------
>tr|G3NR20|G3NR20_GASAC Anoctamin OS=Gasterosteus aculeatus PE=3 SV=1
----------------------------------------SPIDKQQHSKDSVFFRDGERMIDFVLSYVEDKDGE--RKQ--------------------
-------------------------ERRRLYEANLVNVGLELETEDKSEDGKTFFVKIHAPWEVLATYADVLKVKVPFKND-------------------
---PFRLPEHIM---EPDYFTAPFDKS----FLIDDKETFFSPSTRNRI-YYILSRCSYYRDE----IKRLLNNGTYTAAFPLHD----RSANRESDRYN
LHKHWARFFCFFKEQPLNLIRKYYGEKIGIYFAWLGFYTEMLLFAAIVGTICFIYGFLTYD---N-KEICSEEGNIVMCPLCDKKCGYWKLNTTCNSSWL
SLFTINEQC-SSP------Y-WGFGFWKRRQARLEYEWDLVDFEEEQ-------RPEYETKC---------LNMEPIT-------QCART-LSGATVLLW
ISLIIA-IIG-IAYRLAVYAAFASIKDSALQ--PQLATSVTASCINFVIIMILNLMYEKVAVWITDMECPKTHLEYENKLTVK---FQFVNYYSSCFYVA
FFKG--VGYPGKYEYMFG---NEECDPGGCLIELTTQLVIVMTGKQVW-GNIQEALVPWLMNWWGSRK-------RNHPESL-YSRWEQDHDLQGFLGLF
DEYLEMVIQFGFITLFVASFPLAPLLALINNIIEVRVDAWKLTTQFRRPVAAKAHSIGAWQEILNGMAVLSVVTNAFIVAFTSDMIPRLVYMYAYQP-MN
MKGYINNSLSVFNISAIPLENKPDDGESPSSI-TTCRYRDYRYPSGHEKEYHHTMQFWHILAAKLAFIIIVEHVVFVVKFFVAWMIPDVPSDVRARVKRE
RYLVQEYLHNYEVEKLKIQLSQN-------------------------------------
>tr|H2LMT2|H2LMT2_ORYLA Anoctamin OS=Oryzias latipes GN=LOC101164640 PE=3 SV=1
------------------------------------------IQKQQQSKDSVFFRDGVRRIDFVLSYVDDKDGE--RKQ--------------------
-------------------------ERRRVFEANLVKVGLELEIEDKSDDRKTYFVKIHAPWEVLATYADVLKIKVPFKND-------------------
---PFRLPEPIM---EPDFFTAPFDKS----FLIEDRDKFFLPSTRNRI-YYILSRCSYIRDE----IKRLLNNSTYTAAFPLHD----KSVNCDSDRYN
LYKYWAGFFSFFKEQPLNLIRKYYGEKIGLYFAWLGFYTEMLFFAAVVGTLCFVYGVLTYD---N-KEICSDEGNIVMCPLCDKKCGFWKLNTTCNNRI-
-YLTMLEQC-FLP------F-WEYGFWKRRQARLEYEWDLVDFEEEQ-------RPEYETKC---------LNMEPIT-------KCARI-LSGATVLLW
ISLIIA-IIG-IAYRLAVYAAFASIKDSPLE--PQLATSVTASCINFVIIMILNLMYERVAVWITDM--PKTHLEYENKLTVK---FQFVNYYSSCFYVA
FFKG--VGYPGDYAYMFGKW-NEECDPGGCLIELTTQLVIVMTGKQVW-GNIQEALVPWLMNWWASRK-------RSYPESL-YSRWEQDHDLQGFLGLF
YEYLEMVIQFGFITLFVASFPLAPLLALFNNIIEIRVDAWKLTTQFRRPVAAKAHCIGAWEEILNGMAVLSVVTNAFIVAFTSDMIPRLVYMYAYQP-MN
MKGYINNSLSVFNISEIPLPNRPEDGENPLSI-TTCRYRDYRNPPGHENQYSHTMQFWHILAAKLAFIIIMEHVVFLVKYFVAWMIPDVPSDVKARVKRE
RYLVQEYLHNYEVEKLKIQLSQQ-------------------------------------
>tr|W5UCP5|W5UCP5_ICTPU Anoctamin OS=Ictalurus punctatus GN=ANO5 PE=2 SV=1
----------------------------------------AKVDKNHQSKDSVYFRDGVRRIDFVLSYVDENEGE--RKQ--------------------
-------------------------ERRKQYEANLQKAGLELELEDKSEDGKTYFLKIHVPWAVLATYAEVLKIKVPFKND-------------------
---PFRLPDSVM---EPDYFTAHFDNS----FLIENKDTLFPNSTRNRI-YYILSRCPYNKED----IKRLLNNGTYTSAFPLHD----RSPNCDNERYS
LYQSWARFCRFYKEQPLNLIRRYYGEKIGIYFAWLGFYTEMLFYAALVGLICFIYGLATYD---V-KEICDENGEIIMCPLCDKKCGYWKLNSTCNSTWQ
SHLFDNTATVFFAIFMGIWV-LFLEFWKRRQARLKYEWDLVDFEEEQ-------RPEYETKC---------RNLEPVT-------KCARS-LSGATVLFW
ISLIIA-IIG-IVYRLAVFAALASIKDSPLE--PQLATSVTASCINFIIIMILNFLYERVAIWITDM--PKTHLEYENKLTVK---FQFVNYYSSCFYVA
FFKG--VGYPGKYTYMFNEW-NEECDPGGCLIELTTQLVIVMAGKQVW-GNIQEALVPWLQNWWSSRS-------RSHPESL-YSRWEQDYDLQNFFGLF
YEYLEMVIQFGFITLFVASFPLAPLLALMNNILEVRVDAWKLTTQFRRPVAAKAHSIGAWDEILNMIAVFSVVTNAFIVAFTSDMIPRLVYLYAYHP-LT
MDGYINSSLSIFNISQIPPSNRPDNGENPASVITTCRYRDYRYPPGHPNEYQVTMQFWHILAAKMAFIIIMEHVVFVVKFFVAWLIPDVPSDVKARIKRE
RYLVQEYLHNYEVEKLKEQLSQN-------------------------------------
>tr|W5MHZ7|W5MHZ7_LEPOC Anoctamin OS=Lepisosteus oculatus PE=3 SV=1
----------------------------------------LQIDGQHQSKDSVFFRDGVRRIDFVLSYLDDHTKDGEKKQ--------------------
-------------------------ERRKEYESNLQKAGLELETEDKSEDGKTYFLKVHAPWEVLATYAEVLKIKVPFKND-------------------
---PFRLPDEVM---EPDYFTSPFEKD----FLIDNKDTFFPPSTRNRI-YYILSRCPYWKE-----IKRLLSNGTYTSAYALHD----RALNCESERFT
LYKEWARFLRFYKEQPLNLIRKYYGEKIGIYFAWLGFYTEMLFFAAIVGLICFCYGASTYH---ND-RLAD--GHEILSTMCPL---TWSFIQSLPPRNQ
SHLFDNVGTLFFAIFMGIWE-TIH------FTLISYKWSRSDYEEEW-------DRSTLDFC---------LCMEPLT-------KCARF-LSGATVIFW
IALIIA-IIG-IAYRLAVYAAFASLKDNPLQ--PQMATSVTASCINFVIIMILNFLYERVAIWITDM--PRTHLEYENRLTMK---FQFVNYYSSCFYVA
FFKG--VGYPGKYIYMFAKW-NEECDPGGCLIELTTQLVIVMAGKQVW-GNIQEALVPSHFPKRRRCR------LT----------CEMFHEMVQLS-VL
LSSPNAVIQFGFITLFVASFPLAPLLALVNNIIEIRVDAWKFTTQFRRPVAAKAHSIGAWQEILNGIAIVSVVTNAFIVSFTSDMIPRLVYYYQYSS--S
MEGYINNSLSIFNISQFSDQNRPENGENPITVDTTCRYRDFRFPPGHEKEYSHNMQFWHVIAAKLAFIIPGQHVVFMVKFFVAWLIPDVPTDVKARVKRE
RYLIQEYLHNYELERLKNQLSQQ-------------------------------------
>tr|W5LEX6|W5LEX6_ASTMX Anoctamin OS=Astyanax mexicanus PE=3 SV=1
----------------------------------------ATVDKQHQSKDSVYFRDGKRRIDFVLSYVEDKE-D--RKQ--------------------
-------------------------ERRKLYEENMQKAGLELELEDKTEDGKTYFLKIHAPWEVLATYADVLKIKVPFKND-------------------
---PLLLPDHVM---DPDYFTSPFDKS----FLIDDKETLFPPSTRNRI-YYILSRCFYNRDD----IKRLLNNGTYTSAFPLHD----KSTHCESERYS
LYRYWARFFRFYKEQPLNLIRKYYGEKIGIYFAWLGFYTEMLFYAALVGLICFIYGAATYD---V-KEICDDDGQIVMCPLCDKKCGFWKLNSTCNSTWQ
SHLFDNTATVFFAIFMGIWV-LFLEFWKRRQARLEYEWDLVDFEEEQ-------RPEYETKC---------RNMEPVT-------KCARA-LSGATVLFW
ISLIIA-IIG-IAYRLAVFAALASVKDSPME--PQLATSVTASCINFVIIMILNFFYERVAIWITDM--PKTHLEYENKLTIK---FQFVNYYSSCFYVA
FFKG--VGYPGKYTYMFNG--NEECDPGGCLIELTTQLVIVMTGKQVW-GNIQEALLPWLKNWWSSRK-------RSHPESL-YSRWEQDYDLQNFFGLF
YEYLEMVIQFGFITLFVASFPLAPLLALMNNILEVRVDAWKLTTQFRRPVAAKAHSIGAWDEILNMIAVFSVVTNAFIVAFTSDMIPRLVYLYAYHP-LT
MQGYVNNSLSIFNISQLHSDNTPDPGENPASVITTCRYRDYRYPPGHEYEYSHTMQFWHILAAKMAFIIIMEHVVFVVKFLVAWLIPDVPSDVQARVKRE
RYLVQEYLHNYEVDKLKKQLNEM-------------------------------------
>tr|E7F4N6|E7F4N6_DANRE Anoctamin OS=Danio rerio GN=ano5a PE=1 SV=1
----------------------------------------AEVDKQQQSKDSVYFRDGVRRIDFVLSYIDDKDGE--KKQ--------------------
-------------------------DRRKVFEANLQKAGLEVETEDKSEDGKTYFLKIHVPWEVLATYADVLKIKVPFKND-------------------
---PFRLPDHVM---EPDFFTSTFDKS----FLIEDKETLFPASTRNRI-YYLLSRIPYST------IKRLLNNGTYTSAFPLHD----RSDNCESERYS
LYKNWARFSSFYKEQPLNLIRKYYGEKIGIYFAWLGFYTEMLSYAAVVGLLCFIYGVATFD---N-REICNETGQIVMCPLCDKKCGYWKLSTTCSSSWQ
SYLFDNAATVFFAIFMGIWV-LFLEFWKRRQARLEYEWDLVDFEEEQ-------RPEYESKC---------LNMEPLT-------KCARS-LSGATVLFW
ISLIIA-IIG-IAYRLAVFAAFASIKDSPLE--PQFATSVTASCINFVIIMVLNFLYERVAIKITDM--PKTHVEYENKLTIK---FQFVNYYSSCFYVA
FFKG--VGYPGNYAYMFGPW-NEECEPGGCLIELTTQLVIVMVGKQVW-GNIQEALVPWLRNWWVSRS-------RNHPESL-YSRWEQDHDLQNLLGLF
YEYLEMVIQFGFITLFVASFPLAPLLALMNNILEVRVDAWKFTTQFRRPVAAKAHSIGAWEEILNMIAVFSVVTNAFIVSFTSDMIPRLVYQYVHNT-AS
MSGYITHSLSIYNISEFPPENRPDDDENPDGNYTTCRYRDYRYPPGHEKQYTHNMDFWHILAAKLAFIIIMEHVVFVVKFFVAWLIPDVPSDVKARVKRE
RYLIQEYLHDYEVEKLKNQLSLN-------------------------------------
>tr|A0A087X9R6|A0A087X9R6_POEFO Anoctamin OS=Poecilia formosa PE=3 SV=1
----------------------------------------SETERLQPNRDTVFFRDGVRRIDFVLSYVDDKDER--KQ---------------------
-------------------------ERRKEFEANLQKEGLELETEDKSKDHKTYFLKIHAPWEVLATYADVLNIKVPFKSD-------------------
---PFRLPDHIM---QTDYFTYPFDKN----FLINDKETFFPPSTRNRI-FYILARVPYYREG----IKRLLNNGTYTAAFPLHD----RAAECESERFN
LYKHWARFLCFYKEQPLNLIKKYYGEKIGIYFAWLGFYTEMLFFAAVMGVICFTYGALSYG---N-EEICDANGSILMCPLCDKKCPFWKLNSTCFSSWQ
SHLFDNEGTIFFAIFMGIWV-LFLEFWKRRQARLEYEWDLVDFEEEQ-------RPEFEIKC---------ENMEPVT-------KCARF-FSGATVIFW
ISLIVA-IIG-IAYRLAVYAAFASIKDPMIQ--PQLATSVTASCINFVIIMILNFFYEKVAIWITDM--PKTHLEYENRLTIK---FQFVNYYSSCFYVA
FFKG--VGYPGKYSYMFGNF-NEECDPGGCLIELTTQLVIVMAGKQVW-GNI--ALLPLMRNWWSSRK-------RHNPENH-YSRWEQDYVLLNFIGLF
YEYLEMVIQFGFITLFVASFPLAPVLALFNNILEIRVDAWKFTTQFRRPVASKARNIGAWQEILNSVAILSVVTNAFIMAFTSDMIPRMVYLYAYSK-AS
MSGYINNSLSVYNISQIHPDNMPE--E--NST-TTCRYRDYRYPPGHERQYTHTMQFWHILAAKMAFIIIMEHVVFVVKFFVAWLIPDVPSDVKARIKRE
RYLIQEYLHKYEVERLKVQLSAS-------------------------------------
>tr|G3PSB7|G3PSB7_GASAC Anoctamin (Fragment) OS=Gasterosteus aculeatus PE=3 SV=1
----------------------------------------LQTKKLQQNTDTVFFRDGVRRVDFVLSYVDDKDGE--KKQ--------------------
-------------------------ERRRAFEANLEKDGLELETEDKSKDQKTYFLKIHAPWKVLATYADVLKIKVPFKSD-------------------
---PFRLPEHVM---EPDYFTYPFDKT----FLINDKDTFFPPSTRNRI-YYILARCPYYKEG----IKRLLSNGTYTAAFPLHD----RAAECESERFN
LYQHWARFLIFYKEQPLNLIRKYYGEKIGIYFAWLGFYTEMLFFAAVMGVICFTYGLLSYD---N-KEICDANGSIVMCPLCDKKCPFWKLNSTCLSSWQ
SHLFDNEGTIFFAIFMGIWV-LFLEFWKRRQARLEYEWDLVDFEEEQ-------RPEFEIQC---------LNMEPVT-------KCARF-LSTATVIFW
ISLIVA-IIG-IAYRLAVYAAFASIKDPMIQ--PQLATSVTASCINFVIIMILNFFYERVAIWITDM--PKTHLEYENRLTMK---FQFVNYYSSCFYVA
FFKG--VGSPGDYTYMFGPW-NEECDPGGCLIELTTQLVIVMSGKQLW-GNI--ALLPLIRNWWSSRK-------RHHPENR-YSRWEQDHALLNFLGLF
YEYLEMVVQFGFITLFVASFPLAPLLALFNNILEIRVDAWKFTTQYKRPVASKARNIGAWQEILNAVAILSVVTNAFIMAFTSDMIPRMVFLYSYDE-KS
MRGYVNNSLSVYNISHIPERNMPE--ERDDST-TTCRYRDYRYPPGHQKQYTHTMQFWHILAAKMAFIIIMEHVVFVVKFLVAWMIPDVPTGVKARFKRE
RYLIQEYLHNYEVERLKLQLSAS-------------------------------------
>tr|I3J462|I3J462_ORENI Anoctamin OS=Oreochromis niloticus GN=LOC100704073 PE=3 SV=1
-----------------------------------------QTDKLHPSKDTVFFRDGVRRIDFVLSYVDDKDGE--KKQ--------------------
-------------------------ERRRAFEANLEKTGLELETEDKSKDQKTYFLKIHAPRDVLATYADVLKIKVPFKSD-------------------
---PFRLPGNIM---EPDYFTYHFDKT----FLIGDKDTFFPPSTRNRI-FYILSRCAYYKEG----IKRLLSNGTYTAAFPLHD----KGAE---ERYN
LYKHWARFLCFYKEQPLNLIKKYYGEKIGIYFAWLGFYTEMLFLAAVVGLICFIYGVLSYD---N-KEICDPKGSIMMCPLCDKNCTFWRLDSTCLSSWQ
SHLFDNEATVFFAMFMGIWV-LFLEFWKRRQARLEYEWDLVDFEEEQ-------RPEFEIKC---------LNMEPLH-------RCARY-LSGATVTFW
ISLILA-ITG-IAYRLAVYASFASIGNHGTL--PQLATSVTASCINFVIIMILNFFYEKVAIWITDM--PKTHLEYENRLITK---FQFVNYYSSCFYVA
FFKG--VGYPGNYTYMFGKW-NEECDPGGCLIELTTQLLIVMAGKQLW-GNI--ALLPLMRNWWSSRK-------RHNPENH-YSRWEQDHVLQNFLGLF
YEYLEMVIQFGFITLFVASFPLAPLLALFNNILEIRVDAWKFTTQFRRPVASKARNIGAWQEILNSVAILSVVTNAFIMAFTSDMIPRMVYLYAYSN-TS
MKGYINSSLSEYRIPDFYG---SS--SNIGLS-GLYRYRDYRHPPGHENEYTHTMQFWHILAAKMAFIIIMEHVVFVVKFFIAWMIPDVPSDVKARIKRE
RYLIQEHLHNYEVEKLKLQLSAS-------------------------------------
>tr|H2LP37|H2LP37_ORYLA Anoctamin OS=Oryzias latipes GN=LOC101167353 PE=3 SV=1
----------------------------------------IETDKLQPTRDTVFFRDGVRRIDFVLSYVDDKDEK--KQ---------------------
-------------------------ERRRAFEANLEKTGLQLETEDKSKDQKTYFLKIHAPWDVLATYADVLKIKVPFRSD-------------------
---PFRLPDDII---QCDYFTYPFDKN----FLIEDKDTFFPPSTRNRI-FYILARCPYYAEG----IKRLLSNGTFNAAFPLHD----KADDGESERYN
LYKHWARFLCFYKEQPLNLIRKYYGEKIGIYFAWLGFYTEMLFFAAVMGLICFTYGVLSYD---N-KEICDPDGSIVMCPLCDKKCPFWKLNSTCLSSWQ
SHLFDNEGTVFFAIFMGIWV-LFLEIWKRRQARLEYQWDLVDFEEEQ-------RPEFEIKC---------INSEPFS-------KCARF-LSATTVLLW
ISLIVA-IIG-IAYRLAVYAAFASIKDPLIQ--PQLATSVTASCINFAIIMILNFFYEKVAVWITDM--PKTHLEYENKLTMK---FQFVNYYSSCFYVA
FFKG--VGYPGAYSYMLGNL-NEECDPGGCLIELTTQLVIVMAGKQLW-GNV--ALLPLMRNWWSSRK-------RHNPENH-YSRWEQDYVLQNFLGLF
YEYLEMVIQFGFITLFVASFPLAPLLALFNNILEIRVDAWKFTTQFRRPVASKARNIGAWQEILNAVAILSVVTNAFIMAFTSDMIPRMVYLYVLSK-RS
MSGYVNSSLSIYNISQIHPQNMPE--E--RST-TTCRYRDYRNPPGHQREYDHNMQFWHILAAKMAFIIIMEHVVFVVKFFVAWMIPDVPSDVKARIKRE
RYLIQEYLHNYEVERLKMQLSAS-------------------------------------
>tr|A1A5Z4|A1A5Z4_DANRE Anoctamin OS=Danio rerio GN=ano5b PE=2 SV=1
----------------------------------------REIDKFDQNRDSVFFKDGVRRIDFVLSYVDDKEGD--KKA--------------------
-------------------------ERRREFEANLEKAGLELETEDKSDDRKTHYLKIHAPWEVLATYADVLKIKVPFKSD-------------------
---PFRLPENIM---EPDYFTAPFDKS----FLIDDKDTFFPPSTRNRI-YYILTRCPYYKED----INRLLNNGTYTSAYPLHD----KAMQCESERYH
LYRYWARFLCFYKEQPLNLIKKYYGEKIGIYFAWLGFYTEMLFYAAVMGVICFVYGVLSYE---N-KEICDPKGMIVMCPLCDKKCSYWKLNSTCLSSWQ
SHLFDNEGTVFFAMFMGIWV-LFLEFWKRRQARLEYEWDLVDFEEEQ-------RPEYEQKC---------LNMEPFP-----SK-CARF-LSGATVLFW
TCLIVA-IMG-IAYRLAVYAAFASVKDSSIQ--PQLATSVTASCINFVIILILNFLYEHVAIWITDMI---THLEYENKLTMK---FQFVNYYSSCFYVA
FFKG--VGYPGNYSYMFGKW-NEECAPGGCLIELTTQLLIVMAGKQMV-GNVQEALLPLVRNWWSSRK-------RSHPEST-YSRWEQDHDLQNFFGLF
YEYLEMVIQFGFITLFVASFPLAPLLALFNNILEVRVDAWKFTTQFRRPMAAKARNIGAWEEILNVVAIMSVVTNAFIMAFTSDMIPRLVYLYAYHP-AN
MTGYITNSLSIYNISQIPEDNLPEAGENPSSTITTCRYRDYRYPPGHLRQYTHTMQFWHILAAKLAFIIIMEHVVFVVKFFVAWLIPDVPSEVKARIKRE
RFLVQEYLHNYEVEKLKMQLSQS-------------------------------------
>tr|B4DZA5|B4DZA5_HUMAN Anoctamin OS=Homo sapiens PE=2 SV=1
----------------------------------------PEFEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKG--------------------
---------------------EKQRRKRQAYESNLICHGLQLEATRS-LDDKLVFVKVHAPWEVLCTYAEIMHIKLPLKND-------------------
---VLSVDESII---EQEFFTAPFEKN----FYIVDRDAFFNPATRSRI-YFILSRVKYQVI-----INRLVNSGIYKAAFPLHD----QSPSCPNERYL
LYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQD---C-KEVCHPDGKIIMCPQCDRLCPFWKLNITCESSKK
LCIFDSFGTLVFAVFMGVWV-LFLEFWKRRQAELEYEWDTVE-L--Q-------RPEYEARC---------IDEEPFT---AW--KCIRI-LCASAVFFW
ILLIIA-VIG-IVYRLSVFIVFSAKPKNITD--PQTATSITASIISFIIIMILNTIYEKVAIMITNF--PRTQTDYENSLTMK---FQFVNYYSSCFYIA
FFKG--VGYPGDPVYWLGKY-NEECDPGGCLLGLTTQLTIIMGGKAIW-NNIQEVLLPWIMNLIG-----RF--HVSGSEKI-TPRWEQDYHLQPMLGLF
YEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYPPYGD-YT
MEGYINNTLSIFKVADFKNKSKGNPY-------TTCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFIIVMEYLALLPRLGHSGMILAH---CNLRLPVD
CCMCYRFVDEIRLSDFIDSLYYI-------------------------------------
>tr|F6SVE8|F6SVE8_HORSE Anoctamin OS=Equus caballus GN=ANO6 PE=3 SV=1
----------------------------------------PETAEFNGKSDALYFNDGQRRIDFVLVYEDERRKETNKKG--------------------
---------------------VKQRRKRQAYESNLICDGLKLEATRS-VDDKLVFVKVHAPWEVLCTYAEIMHIKLPLKND-------------------
---FFQVDENII---EQEFFTAPFEKN----FYIQDRDTFFNPATRSRI-YFILSRVSYEVK-----INRLVNSGIYKAAFPLHD----PSVSCPNERYL
LYREWAHPRSFYKKQPLDLIRKYYGEKIGIYFAWLGYYTKMLLLAAVVGVACFLYGYINQD---C-KEVCDPRGEIIMCPQCDKGCPFWRLNITCESSKK
LCIFDSFGTLVFAVFMGIWV-LFLEFWKRRQAELEYEWDTVE-L--Q-------RPEYEARC---------INEEPFT---AF--KCIRM-VCASAVLFW
VLLIIA-VIG-IVYRLSVFIVFYAKPKASTD--PQTATTITASIISFIIIVILNMMYEKVAIMITNF--PRTQTDYENSLTMK---FQFVNYYSSCFYIA
FFKG--VGYPGDPVYWLGKY-NEECDPGGCLFELTTQLTIIMGGKSIW-NNILEVVFPWVMNICR-----LY--FASSTEKK-TPRWEQDYHLQLMLGLF
YEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKMTTQYRRMVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYPPYGN-YT
MKGYINNTLSIFNTSDFTERSRENLD----------EYRDFRYPPGHPQQYKHNIYYWHVIAAKLAFIIVMEHLIYSVKFFISYAIPDVSKSTKSKIKRE
KYLTQKLLHENHLKDMTKSFGVI-------------------------------------
>tr|F6YBM4|F6YBM4_HORSE Anoctamin OS=Equus caballus GN=ANO3 PE=3 SV=1
----------------------------------------SKNDMNYIASSGLLFKDGKKRIDYILVYRKSNIQ--------------------------
------------------------YDKRNTFEKNLRTEGLMLEKE---ANPDIMFIKIHIPWDTLCKYAERLNIRMPFRKK--------SMGR-----LQ
--HPMVLDKTAFP--NSDCYTGPFSRA----FIINNKDTFFSNATRSRI-YHMLQHTKYEHG-----ICKLINNGSYIAAFPPHE----SLYGPQNNRHL
LYERWARWGMWYKHQPLDLI-LYFGEKIGLYFAWLGWYTGMLIPAALVGLCVFFYGILTMN---SSNEICKA-TEVFMCPRCDKNCSLQRLNDSCIYAKV
SYLFDNGGTVFFAIFMAIWA-VFLEFWKRRRSTLTYTWDLIEWEEE--------RPQFEAK-----YY---VNPEPFS-------KVTRL-VSMSGIFFM
ISLVIT-VFA-VVYRLVVMERFASFWNFI-Q--QF-ATSAAAVCINFVIIMLLN-AYEKIAYFLTNL--PRTESEWENSFALK---FQFVNLNSSIFYIA
FFLG--VGHPGHYNKLFN--RLEECHPSGCLIDLCLQMGVIMFLKQIW-NNFMEG-YPLIQNWWSRHKIKQEI-------NASIPQWENDWNLQPMHGLM
D--LEM-LQFGFTTIFVAAFPLAPLLALLNNIIELRLDAYKFVTQWRRPLPARATNIGIWYGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGP-NC
LKGYVNNSLSFFDLSELGMGKSE-HLGPPHLCTSNSLYRDYRGPPWSSKPYEFTLQYWHILAARLAFIIVFEHLVFGIKSIIAYLIPDVPKHLYDRIRRE
KYLVQEMMYEAELEHLQQERR---------------------------------------
>tr|Q4RHQ9|Q4RHQ9_TETNG Anoctamin OS=Tetraodon nigroviridis GN=GSTENG00034215001 PE=3 SV=1
----------------------------------------CPQAEFNDKPDSLFFNDGVRKIDFVMVYEDEDKKDFE-----------------------
---------------------QRRKRRREFFEASLMNMGMELEATQSV-NDKLMFVKVHMPWDMLCTYAEVLHIKLPIQNDWQF----------------
---HFYPNEDLIK--ETEYFTAPFEKNRQEFFHI-DKDSFFTPSTRSRM-RACLLGHCR--------QRRLQG-RLPRPRLPVQRD---AAEVLRREDRH
LL----------RLVGLLHHHAHAGGGPGLFHLWIQDSGDQHVEVEAQGSAAVTLGFHFS-SWHCSKEVCDPEGKIVMCPQC-RECKYWRLNSTCEASKK
LCIFDNYGTLVFAVFMAIWV-LFLEFWKRYQAELEYQWDTVEFLEQE----QPARPEYEAKCIYER-----KNKEFT-----GCGRCVRVSLGIGTVIFW
ILLILA-IVA-TVYRLAAFFAFSARLRAQEY--PQMATSVTASLISFVVIMVLNVLYERVAIWITNFELPRTKTDYENSLTLK---FQFVNYYSSCFYIA
FFKG--VGFPGDPVYILGKYPGLQCDPGGCLIELTTQLSIIMGGKAIW-NNIQEVLLPWVKNLIFRYCTSAT-------SEKVIPRWEQDYRLQPFLGLF
YEYLEMVIQFGFVTLFVASFPLAPVLALVNNLFEVRVDAWKITTQFRRVVPEKAQDIGAWQPILQGVAILAVATNAMIIAFTSDMIPRLVYYWSFSVTHT
MEGYINSSLSVFDTSNFSNDSRP-------TG-SSCRYRDFRFPPGH-RQYQFNMHYWHVIAAKMAFIIVVEVGPGPPEGEANPCVSSAARRLPDQVRPV
LRDSRRAVRRAGADQAGEVPDPG-------------------------------------
>tr|F7CQ03|F7CQ03_MONDO Anoctamin OS=Monodelphis domestica GN=ANO3 PE=3 SV=2
-----------------------------------------KKEMKVTATPSLFFKDGKKRIDYILVYKKSSLQ--------------------------
------------------------VEKRSTFERNLREEGLMLERE---TNSDIMFVKIHCPWDTLCKYAERMNIRMPFRKK--------TLNS-----LY
--RPMQLDKEALP--ETDCYTAPFSRA----FTITNKDTFFNNSTRSRI-HHVLQRTKYEDG-----INKLLNNGTYEASFPPHE----RHHGAKNHRHL
LYKRWACWGMWYKYQPLDLI-RYFGEKIGLYFAWLGWYTGMLIPAAFVGLFVFLYGVFTMH---SSKEICQA-TEILMCPMCERSCMLQKLNESCIYAKV
THLFDNGGTVFFAIFMAIWA-VFLEFWKRRRAVLTYDWDLIDWEEEE-------RPQFER------KY---VNPEPFM-------KLLRL-ISILGIFLM
ISLVLT-VFA-VVYRLVAMEHFASFWYFV-K--QF-ATSGTGVCINFVIIMFL-VVYEKVAFFLTNL--PRTELEWENSYALK---FQFVNLNSSIFYIA
FFLG--SGRPGKYNKLFD--RLEECHPSGCLIDLCLQMSVIMVLKQTW-NNFMEG-YPLFHNWWTQHKIKRNE--QV----LKLPQWEKDWNLQPMHGLI
D--LEM-LQFGFVTIFVAAFPLAPLLALMNNIIEIRLDAYKFVTQWRRPLPARATNIGIWYGILEGIGVLAVITNAFVIAITSDYIPRFVYAFRYGP-RC
LKGYVNSSLSVFDLSELGP-G---H-------SGYCRYRDYRAPPWSSNPYELTLQFWHVLAARLAFIIVFEHLVFGIKSFIAYLIPDMPKDLSDRVRRE
KYLVQEMMYDAELEHLQKQRK---------------------------------------
>tr|W5MCV4|W5MCV4_LEPOC Anoctamin OS=Lepisosteus oculatus PE=3 SV=1
----------------------------------------LCPEDDTQCGQGLYFHDGKRKVDYILTYHIKKPSGSK--KYSS-----------------
-RFS-------------E--NDDKRFRREEFEGNLTEMGLELERDEDTKTPGVGFVKIHAPWNVLCREAEFMKIKMPTKKVYEVKQGSNLVEKINAFINK
VTEPLHPNVEENRITTVKHLSYPFSREKQHLFDLSDKDSFFDSKTRSSIVYEILKRTKCTKAKYSM-MTSLLANGVYTAAYPLHDGDTNGENRAPNDRKL
LYEEWASYSVFYKYQPIDLIRKYFGEKIGLYFAWLGVYTQMLIPASIIGIIVFLYGCATVDDDIPSMEMCDKRNNITMCPLCDKVCGYWKLSTGCATARA
SHLFDNPATVFFSIFMALWATMFMEHWKRRQMRLNYKWDLTGFEEEEEAVKDHPRAEYEFRVMQKTLKKEGVMGGTEKEKLTCRDRMPAYVTNLVMMLLM
IGVTFAIVFGVILYRVSTKAALAMSSNPVTRSNVRLTVKATAAIINLVIILILDEVYGAIARWLTLLEVPKTDKSFEERLIFKTFILKFVNAFTPIIYIA
FFRGRLVGRPGNYVYAFKSFRMEECAHGGCLMELCIQLSITMLGKQLIQNNLFEIGIPKLKKLIRYIKSKRRPFQE-EEREKKLQHYETDYFLDPFAGLT
PEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPIAARAKDIGIWYNILRGIGKIAVIINAFVISFTSDFIPRLVYQYMYSPDGS
MHGFVNHTLSYFNVSHFQEGTEPHIPSNLGYKVEICRYKDYREPPWSPSAYDISKEFWAVLAARLAFVIVFQNVVMFMSDFVDWLIPDIPKDISQQIHKE
KILMVELFMKEEQGKLNMLESLV-------------------------------------
>tr|A0A0P7VB60|A0A0P7VB60_9TELE Anoctamin-1-like OS=Scleropages formosus GN=Z043_110819 PE=4 SV=1
----------------------------------------KAGEAASGDQHDLCSKDGQKHMDYILTYSTKKLFSDLHP--S------------------
-LS-L-----------KE--KEEKVLCREEFEDNLKKMGLHLEKDES-RISGVGFLKIHAPWDILCREAEFLKLKMPTKEFYQAT-PQHKMRKLNAFFKR
ITAPLLPNVGDTETEDIKKVCYPFSREKLHLFDLSDMDSFFDTKTRSLIVFEVLKRAKCNRGENSW-LNSLIAHGVYTEAYPLHD--------------V
LYREWASYSNFYKYQPISLIRKYFGEKIGLYFAWLGLYTQMLIFAAIVGVLVFLYGCITVDDDIPR-QICDKRNNITMCPLCDKSCSYWKLTMACGTARA
SHLFDSTATVLFSIFMALWAAMFMESWKRRQMRLNYMWDLTNFEEEE----DHPRADYKIKVHQKTLNRMQ----AKAAKLTWRDRMPAYMTFIAIMLLM
FLMTFAILFGVIIYRVTTQASLQMSSMPSIRANVRLTVKSTAVIINVVVILILDEVYSKIARWLTILEVPKTDKSFEQRLILKTFILKFLNAFSPIFYIA
FIRG-LIGRPGNYLYIYKSYRMEECAHTGCLMELCIQLSITMLGKQLIQNNLFEIGIPKLKKLIRRIKTKRAPV-QEEQDDKDLKRYEADFFLEPFVSLN
PEYMEMIIQFGFVTLFVASFPLAPLFALLNNVIEIRLDAKKFVAELRRPVAARAKDIGIWYNLLRGISKAAIIVNAFVIAFTSDFIPRLVYQYGYSPDGT
MHGFINHTLSYFNVSHFQAETHPLQPLHLGYKVEVCRYKDYRMAPWSFNPYDISKVYWAILAGRLAF-----NVVMLLSDFVDWVIPDIPKEIITRIYEE
KMQMVEFFMREEHSLYSMPMLDN-------------------------------------
>tr|A0A0P7Z527|A0A0P7Z527_9TELE Uncharacterized protein OS=Scleropages formosus GN=Z043_105027 PE=4 SV=1
----------------------------------------LVPEENTHCRQGLYFQDGQRRVDYVLTYHIKKQSSSR--RHSS-----------------
-RLT-------------D--NDDKRFCRDEFESSLMEMGLELEKDEHTKTPGVGFVKIHAPWHVLCREAEFMKLKMPTKKVYEVKQGSNLVEKINTFITK
LTEPLHPNVEENRIQNVKHLSYPFSREKQHLFDLSDRDSFFDSKTRSSIVFEVLKRTKCTKSKHSM-ITSLLANGVYMAAYPLHD--------------L
LYEEWASYSVFYKYQPVGLIRKYFGEKIGLYFAWLGVYTQMLIPASLVGVIVFLYGCATVDDDIPSMEICDKRNNITMCPLCDRACSYWKLITACGTARA
SHLFDNPATVFFSIFMALWAAMFMEHWKRRQMRLNYIWDLTGFEDEE----DHPRAEYEFRVMQKALKKEH----PEKVKLTCKDRLPAYMTNLVMMLFM
IGVTFAIVFGVIVYRISTTSALYMSSNPTTRSNVRLTVKTTAAIINLVVILILDEVYGAVARWLTILEVPKTDKSFEERLIFKTFILKFVNAFTPIIYIA
FFRGRLVGRPGSYLYVFESYRMEECAHGGCLMELCIQLSITMLGKQLIQNNLFEIGIPKLKKLIRYIKSKRRAFQE-EEQDKKLQRYETDHFLEPFAGLT
PEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVVELRRPIAARAKDIGIWYNILRGISKVAVIINAFVISFTSDFIPRLVYQYMYSPDGS
MHGFVNHTLSYFNVSDFQEGKDPLEPTDLEYKVEICRYKDYREPPWSPTPYEISKEFWTVLAVKLAFVIVFQNVVMLMSDVVDWIIPDIPKDISVQIHKE
KILMVELFMKEEQGKMQTLESKD-------------------------------------
>tr|A0A060VT94|A0A060VT94_ONCMY Anoctamin OS=Oncorhynchus mykiss GN=GSONMT00077238001 PE=3 SV=1
----------------------------------------LTPEENTQCQHGLYFQDGERRVDYILTYHIKKPSSSRSNRQSS-----------------
-RFT-------------D--NDDKRYRREEFEGNLRDMGLELEKDEDTKTPGVGFVKIHAPWHVLCREAEFMKLKMPTKKVYEVKQCSGVGAKINTLVNK
ATEPLHPNVEENRGQHVKHLSYAFSREKQHLFDLSDRDSFFDSKTRASIVFEVLKRTKCTKAKYSM-ITSLLGSGVYTAAYPLHDGDVDGENVEPNDRKL
LYEEWASYSVFYKYQPIGLVRKYFGEKIGLYFAWLGLYTQMLIPASLVGVIVFLYGCATVDNNIPSMEICHPRNNITMCPLCDRACNYWKLKEACGTARA
SHLFDNPATVFFSIFMALWAAMFMEHWKRRQMRLNYEWDLTGFEEEEVSLSDHPRAEYELCVMQKSLKKEH----TEKEKLTCRDRLPAYMTNIVMMLLM
IGVTFAIVFGVILYRISITAALHMSNNPTTRSNVRLMVKTTAAIINLVVILILDEVYGAVARWLTVLEVPKTDRSFEERLIFKTFVLKFVNAFTPIIYIA
FFRGRLVGRPGSYLYVFESYRMEECAHGGCLMELCIQLSITMLGKQLIQNNLFEIGIPKLKKLIRYIKSKRRSFQE-EEREKKLQRYETDHFLEPFAGLT
PEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVAELRRPVAARAKDIGIWYNLLRGVAKVAVIINAFVISFTSDFIPRLVYQYMYSPDGS
MHGFVNHTMSYFNVSDFQDGKEPMDPHHLGYQVEMCRYKDYREPPWSNTPYVVSKEFWAVLAARLAFVIVFQNVVMLMSDIVDWLIPDIPKDISLQIHKE
KILMVELFMKEEQGKMQFIDSMT-------------------------------------
>tr|A0A087YP15|A0A087YP15_POEFO Anoctamin OS=Poecilia formosa PE=3 SV=2
----------------------------------------PEIGKQKLSKDSVFFRDGMRRIDFVLSYVDDKDCE--KKQ--------------------
-------------------------ERRRIYEDNLKNAGLELETEDKSEDGKTYFVKIHAPWEVLATYADVLKIKVPFRTD-------------------
---PFRLPKNIM---EPDYFTAPFSKS----FLIDNQDTFFPPSTRNRI-YYILSRCLYVSEN----IKRLLNNGSYTSAFPLHD----RSVNCESERYD
LYKHWARFFCFFKEQPINRIRKYYGEKIGIYFAWLGFYTEMLLFAAVVGAICFLYGFLTYD---N-KEICSDEGKIVMCPLCDKKCSYWKLNTTCNSSWQ
SHLFDNVATVFFAIFMGIWV-LFLEFWKRRQARLEYEWDLVDFEEEQ-------RPEYETRC---------ENLEPIT-------KCARS-LSGATVLLW
ISLIIA-IIG-IAYRLAVYAAFASIKDSPLE--PQLATSVTASCINFVIIMILNLMYEKVAVWITDM--PKTHLEYENKLTVK---FQFVNYYSSCFYVA
FFKG--VGYPGKYAYMFG---NEECDPGGCLIELTTQLVIVMTGKQVW-GNIQEALLPWVMNWWGSRK-------RSHPESL-YSRWEQDHDLQSFLGLF
YEYLEMVIQFGFITLFVASFPLAPLLALFNNIIEIRVDAWKLTTQFRRPVAAKAHSIGAWEEILNGMAVLSVVTNAFIVAFTSDMMPRLVYMYAYQP-MN
MKGYINNSLSVFNVSEFEDSSRPEEAENPM---TTCRYRDYRYPPGHEKQYFHTMQFWHILAAKLAFIIIMEHVVFLVKYFVAWLIPDVPSDVRARVKRE
RFLVQEYLHDYEVNKLKIQLSQQ-------------------------------------
>tr|T1HSW8|T1HSW8_RHOPR Anoctamin (Fragment) OS=Rhodnius prolixus PE=3 SV=1
------------------------------------------------DRDSLFFKDCKRRIDLVMVYEEDDIELGVL----------------------
---------------------TIRMETRQQFLKNLEKEGLELELEKKQFDQKTYFLKIHVPWKVLTRYAEVMNLKMPIKFLAWVIECEE-----------
-RMLFDLNPNVIA--EPSFYTATFSRDREEQFVVDRE-TFFTSAQRSQI-FQILLRTKYDE------IRRLLNNGTYLSVFPLHE------NGLVFDRRL
LYLEWARPGRWYKKQPLWLVRKYFGDKIALYFAWLGFYTEMLIPPAIVGLLCFLYGLSTMDDNIPSKEICNANGNITLCPLC-KVCSYQKLVDSCVFSKI
TYLFDNPATVFFAIFMSFWA-TFLELWKRRQAIIAWEWDLQYTEE-D----EEARPEFEATVK---T----TNKEPA------GQKAWRMVVTSSTVLFM
IMVVLS-VLG-IVYRLSVVTYIYEGGNSFVK--AKIFTSITGATLNLIIIMILTKCYHSIAVWLTNQENPRTQIEYEDSYTFK---FEFMNFYSSLIYIA
FFKG--FSYPG---------KGDVCDPAGCLFELCIQLAIIMVGKQFF-YNFVELGYPAVLNWWRKRSHRSL-----KDRSREYTRWEKDYQLQDPLALF
EEYLEMGKYFQKKKSYENGL-------------------QILHLQSRRPLAERVEDIGAWYGILQGVTYCAVVSNAFVIAYTSDYIPRMVYKLVYSPTND
LAGYIDSSLSVFNTSHYLDDMGA-------WE-DTCQYRGYRNGPDHP-PYGLSPQYWHVFAARLAFVVVFEHIVFALTGIMAYAIPDVPSEIRTQIQRE
RLLSKEAKFEHGIKSNNKEEDEY-------------------------------------
>tr|H2U329|H2U329_TAKRU Anoctamin (Fragment) OS=Takifugu rubripes GN=LOC101076811 PE=3 SV=1
--------------------------------------------KQQHSKDSVFFRDGRRRVDFVLSYVDDKDGE--RKQ--------------------
-------------------------ERRKVYEANLENVGLELETEDKSEDGKTSFVKIHAPWEVLATYADVLKIKVPFKND-------------------
---PFRLPDHIM---EPDYFTAPFNKS----FLIDDQETFFPPSTRNRI-YYILSRCSYLKDE----IKRLLNNGTYTAAFPLHD----RSPNCESERYN
LYKHWARFFCFFKEQPLDLVRKYYGEKIGIYFAWLGFYTEMLFFAAVVGTICFIYGFLTYD---N-KEICSEAGNIVMCPLCDKKCGYWKLITTCNSSWQ
SHLFDNVATVFFAIFMGIWV-LFLEFWKRRQARLEYEWDLVDFEEEQ-------RPEYETKC---------LNMEPIT-------KCARL-LSGATVLFW
ISLIIA-IIG-IAYRLAVYAAFASIKDSPLQ--PQLATSVTASCINFVIIMILNLMYEKVAIWITDM--PKTHLEYENKLTVK---FQFVNYYSSCFYVA
FFKG--VGYPGNYIYMFGEW-NEECDPGGCLIELTTQLVIVMTGKQVW-GNIQEALVPWLRNWWGSRK-------RSHPESL-YSRWEQDYDLQVFLGLF
QEYLEMVIQFGFITLFVASFPLAPLLALFNNIIEVRVDSWKLTTQFRRPVAAKAHSIGAWQEILNGMAILSVVTNAFIVAFTSDMIPRLVYMYAYQP-MN
MKGYINNSLSVFNISEFPGSTAPSQRA---VL-FPCRYRDYRYPPGHQKQYTHTMQFWHILAAKLAFIIIMEHVVFLVKFFVAWMIPDVPSDVRARIKRE
RYLVQEYLHDYEVERLKNQLSQN-------------------------------------
>tr|T1J757|T1J757_STRMM Anoctamin OS=Strigamia maritima PE=3 SV=1
----------------------------------------NKPLYTPSSLETIYFRDGKRKIDYVLAYEEGSMSS-------------------------
---------------------ENKLEKRDVFLENLIEQGLELEKEDKAQDGKTFFIKIYAPWSVLTQYAEIMSLKMPIKVD-------------------
---PFDYDKNLIP--DPPYFTSAFNRQRESQFVINKE-TFFTSAQRSRM-WQILTRTHYSLDD----VMRLLNNGTFKAAFPLHEESKYQMFEGAYTRTL
LYQEWARWGCWYKKQPLQLIRKYFGVKIGIYFAWLGFYTSMLIPPAIVGVLCFLYGVFTLS-SIPVNDICNDKGNFTICPLC-KSCRFKRLHESCFFAQV
SYIFDNPATVFFRFLWLFVT-TFLEFWKRRQARIVWEWDLGNYDEEE----ETTRPEFELQVK---T----INLEPF------WNKALRVAAASSAVLLM
VAVVLA-VFG-VVYRIATATALHSSTAEFIR--AKITVSVTSALINLTIILILDRVYQKIAIILTNLERPRTQTEYENSFTFK---FQSVNFYSSLIYIA
FFKG--FLLSFVSLSHTLSHLLLQCDPAGCLFELCVQLSIIMVGKQVL-NNLKEILFPLVVNWWAARKSK-------ANTKQLYTRWEKDYDLRPTLTLF
YEYLEMVIQYGFITIFVASFPLAPLFALLNNVAEIRIDAFKFVTQVRRPMAARANSIGAWAQILQMISTIAVLVNAFVIAYTSSFIPEMVYRY-NSGNFS
LNGYINDVLAVYNTSDFSAEVRP-------HY-ELCRYRDYRIAPPHP-KYERSIEYWHVFAARLAFVVTFEHLVFVLTSLLAYVIPDAPFDVRTNLRRE
KILGKEALYDAELQKLRNENVN--------------------------------------
>tr|H2YZL6|H2YZL6_CIOSA Anoctamin OS=Ciona savignyi PE=3 SV=1
---------------------------------------------PQRPKTTLYFHDGVRYIDYVIAYEQGDEGK-------------------------
---------------------GKVEELRRKYEENLKEKGLQIEHEP--QDQKTCFVKVHVPWEILLRNAERMKMKMPLKEK----------SCFGSIYRK
MVS-CLLNSEGVE--PD-YYTSEFVRDKMD-FDIKDEKTFFTNSQRSRI-YRLMSETRFGTK-----INNLIGEGGYLAAFPLHE------PANANLRRL
LYWEWARWGRWYKFQPLDLIRLYLGDKVAIYFAWLGFYTEALFYPTFVGFIVFIYSIIACL-YNHSQEVCDETGNLTMCPLC-EDCSYWKLKTSCLASRI
TYVFDNEATIFFAVFMSMWA-MFLEFWKRRQFQLSYEWDLVDYDEER----DLIRPEYEAQVTR---E---LNMEST-----KD-KYTRTCFSLVTVFFW
ILVIIA-VFA-IVYRLAISAIFAVSIDL-LG--PAMLTTITASLLSLIVIMLLNKVYEKVALWLTELELPRTQTEFEDRFTFK---FQFVNFYSYLFYIA
FFKS--TGSPGNYNY-----RWEECDAGGCMYELSIQLIIIMFGKQLW-NNIVELVLPWAQTKYRQWKSQKVS---AEMKDNEYTRWEQDYDLNQFMDLF
YEYLEMVIQFGFVTLFVAAFPLAPVLALINNIIEIRLDANKFICELRRPLAHKCSDIGAWYYLLEFIGNLAVVTNAFTIAITSEAIPKLVYYYVYSL---
--GYVNNSMSYFNTSDFDLRSVPNNRDPFG-------YPGYLSPPNANPPYAFTTQYWHNIAGKLAFIIVVEHVVFLLKRLLDYLIPDRPRKLRDKIRRE
HFLVQNMMFKAETDKLRQQFSRK-------------------------------------
>tr|A0A0N4ZJA1|A0A0N4ZJA1_PARTI Anoctamin OS=Parastrongyloides trichosuri PE=3 SV=1
----------------------------------------PKRICWN--REDCFLSDGISLIDYVLVYKNDIYNLENPEQKQ------------------
---------------------IKNHSKRRIFQSNLKSFGLKIEEMRSEDENKIIYVLISAPFHVLSRQAEILKLKMPVLSEGLF----------------
---SRNNDVEERL--MKLKYRSFFMEEKIECFENNNPELFFGRSERIRL-YDLLLRTKFGFEE----IEKMISRGIYNDAFPLHE------VVERTDREL
LYEYWGLMRSFWRLQPLDLIKRYFGTKIGIYFAWLGYYTKSLFFPSIIGVIIVIIGGITLS-NVPSNEVCGNYENIYLCPAC-KYCNFQILKNNCLYTKI
SYIFYNYYSVLFSVIMCIWS-LFLRGWKRYHSEISYKWGITDFEIED----ETIRPDFRTNIK---R----INEESG------YTKIFKWLCSTITLIVF
ICLVIG-GVG-ITYKMSVAVSLYGSDNELYK--AILIASIVTGMANLCFILVLNKIYNYVAYQLTCWECPRTQNDFDNSFTLK---FQFVNYYSSLFYIA
FVKG--S-------------SGEQCDPSGCMVELVIQLGCIMIGKQFV-AAIIERMLPLFWI----WQRSSKKR-------LVKRQCDKDYLLNSVQYLF
YEYLEMVIQFGFVTFFAAAFPLAPFFAFINNIIEIRIDAMKFIEAFRRPMPGHTKNIGVWEKILEGMSHLSVPINGCIIAFTSDFIPQLFYLYT---KGS
MNGFVDYSLSVYEV---RKK----------NGIETCRFKNFYNN--------NHEDWWKIMVLRCAFVLIFEHVVFCAKLIIVYIIPEIPTKIIYQLQRE
RFLDKKAVLKQHNLDIK-----I-------------------------------------
>tr|A0A0N5BL02|A0A0N5BL02_STREA Anoctamin OS=Strongyloides papillosus PE=3 SV=1
----------------------------------------KSKISWE--KEACFFSDGIRIIDYVLAYEDER-GGESDGDFD------------------
---------------------KTKAVKRKIFQENLTALGLEIEEMPSHLTNRIIFVLIHAPFHVLCKQAEILKLKMPVLSEGWL----------------
---SMKPELEKRF--AKPKFRSPFIEERIECFENHDPDNFFPRAERSRL-YDLLLRTKYSPDI----IERMIARGIYNDAFPLHEQ---T-ISETTDREL
LYRYWASLYSFWRLQPLDLIKRYFGTKIGIYFAWLGYYTKSLIWPSMIGLIVVMIAVSTSI-DIPSNDVCGSDAKVYLCPTC-KYCNFQKLRNNCAYAKL
TYIFDNYYTVIFAAVMCLWG-LFLEGWKRFHSEIAYKWGMLDFEVED----ETMRPDFQSKIK---T----INEEPA------KEKIFKWFCSGMTVLFF
VCLVIA-AVG-IIYRVSFTFSLYGSDNEFYR--AIVITSLLAGLINVCVIMLLNRLYNKLAFQLTCWECPRTQSDFDNSYTLK---FQFVNYYTSLFYIA
FFKG--NSVPNALDK----TSLEQCDPSGCMVELVIQLGTIMIGKQML-TAIIERLLPKFWI----WLASLKNRFENQKGSNVMNQCDLDYGLNQVQYLF
DEYLEMVIQFGFVTLFVTAFPLAPMFALLNNIIEVRIDAQKFVCTFRRPMPAHAKNIGVWEGILSGISYTAVLVNACIIAFTSDFIPKLYYLFFKS-NGD
LQGYMDYSLSYFDATLIHNK----------NDVNVCRFRGFYKPTCKFDDYSVNDDWWKIMVMRCAFVLIFEHFVFALKVLIAYIIPDIPTKIVYQIQRE
RHLSRKAMLNQHDFNFK-----K-------------------------------------
>tr|A0A0N4Z324|A0A0N4Z324_PARTI Anoctamin OS=Parastrongyloides trichosuri PE=3 SV=1
----------------------------------------KSKISWS--KESCFFSDGIRIIDYVLAYEDDKF-TEAENDND------------------
---------------------KTKSVKRKIFQQNLMNIGLEVEEIESHAANRIKFVLIHAPFHVLCKQAEILKLKMPVISEGWL----------------
---SLKPELEKRF--IKPKFRSPFIEERIECFENHDPDNFFPRAERSRL-YDLLLRTKYSQEN----IERMISRGIYDDAFPLHEK---NSDAETTDREL
LYKYWASLYSFWRLQPLDLIKRYFGTKIGIYFAWLGYYTKTLVWPSMIGIIVVIIAGFTAI-DIPSNDVCGSDSKVYLCPTC-KYCNFQLLGNNCVYAKL
TYMFDNYYTVFFAVVMCLWG-LFLEGWKRFHSEIAYKWGMLDFEVED----ETMRPDFQSKIK---T----INEEPT------KEKVFRWFCSGMTVLFF
VFLVIA-AVG-IIYRVSFTFSLYGSDNEFYR--AIVITALLTGFINVCFIMALNRCYNWLAFKLTVWECPRTQSDFDNSYTLK---FQFVNYYTSLFYIA
FFKG--NSVPNALDK----TSLEQCDPSGCMVELVIQLGTIMIGKQMF-TAIIERLLPKFWI----WFASLKNRIEEPKIETKINQCDLDYSLNQVQYLF
DEYLEMVIQFGFVTLFVTAFPLAPVFALLNNIIEVRIDAQKFISTFRRPMPAHAKNIGVWEGILSGISYTAVLVNACIIAFTSDFIPKLYYLFFKS-QGD
LQGYMNYSLSYFDASLINNQ----------NDVHICRFRGFYKPTCKFNEYNVNDDWWKIMVMRCAFVLIFEHFVFALKVLIAYIIPDIPTKIVYQIQRE
RHLSRKAMLNQHDYNFN-----K-------------------------------------
>tr|A0A0N5A4W3|A0A0N5A4W3_PARTI Anoctamin OS=Parastrongyloides trichosuri PE=3 SV=1
-------------------------------------------EIYQ-NVNSTYLSDGKSLVDYVLAFKV------------------------------
---------------------DKLMRARKNFEFNLRARGLKLEIKKGE-DSEVCFTLVHAPFEILLRQAEILYMKMPTLNDGII----------------
---KLDKNIRHRL--EEMYFKETFRRKALHRFVNDSPKEFFSKSDRSRM-YDLLMRTYYRIEN----VQNLLESGSYVAVYPPHE------IEEASDRQI
LYQTWASFTQFYKLQPLDLVKEYFGTRIGIYFAWLGYFTNFLFWPAIFGPLFMLYGVLTAK-DIPSNDICSESSSTFICPSC-TYCDYTQLKDSCLYAKI
TYIVDNFSTAIFAFLMSIWG-LFLEGWKRYNARIAYKWGIYNEGIEH----ETIRPDFQYKVK---K----MNSEPV------SIKLLKLFFSGVSFLFI
VALALA-ILG-LVYRMLLMGTFHSYKSDFRH--GMWIIFITTAIMNLLFIIIMNLVYHKVAYKLTIWECPRTDSEFDNSYTLK---FEFVNNYASLFYIA
FVKG--SGVPGN-------IRVENCDATGCMAELMIQLFVIMCGSQIS-YSILELISPLLCIRFQRLKSIVD--YKNVVNKEELPQYERDYGLYTVLFLF
DEYLEMIIQYGFITLFVAAFPLAPLFAFLNNILEIRTDARKLVSMYQKPTPLHSSNIGMWQIILEYLSNIAVTINALVIAFTTDVIPKSYYY--YT-HGS
LEGYMEYALSYADTSKWDKV----------TNVTTCRFKDFRKPPCSLNHYGFSYEFWRILALKIIFVFLFERIVSSIQSFTSYIIPDVPESITMLQQRQ
KHLRRKSLLESWEKIYHGDNEKN-------------------------------------
>tr|A0A090MXG6|A0A090MXG6_STRRB Anoctamin OS=Strongyloides ratti GN=SRAE_2000007900 PE=3 SV=1
----------------------------------------KDNLSQQ-NINSTYLCDGKSLVDYVMVYKT------------------------------
---------------------EKLISGRKNFEYNLRVRGLKIEIRKSE-DSDICFTLIHAPFNVLLRQAEILYLRMPVRNDGII----------------
---KLNKNIKHRL--EEMYFKETFRQSRLTHFINDKPDIFFSKSDRSRM-YDLLIRTHYKCQD----VQKLLESGIYLAVFPPHE------IDQASDRQI
LYDNWASFTKFYKHQPLDLIKEYFGTKIGIYFAWLGYFTKLLFWPAIIGPLFFIYGLTTAK-DIPSNDICYESSLTYICPSC-TYCDYTQLKDSCLYGKI
TYIVDNFSTGIFAFFMSIWA-LFLEGWKRYNARISYKWGIYNQGIEH----ELIRPDFQYKVK---N----INLEPT------SLKLFKLFFSGVSFLFI
VALALA-ILG-LVYRMILMSTFHSYKTDFRH--GMLIIYVTTAIMNLLFIIIMNLVYHKVAYKLTIWECPRTDSGFDNSYTLK---FEFVNNYASLFYIA
FIKG--SGVPGN-------IRVENCDVTGCMAELMIQLFVIMFGSQLS-YSFFELITPYICINLQKYKIFVD--FKKISNKNDLPEYEKDYGLYQVLFLF
DEYLEMIIQYGFVTLFVAAFPLAPLFAFLNNILEIRSDGRKLISMYQKPTPLHSSNIGMWQIILEYLSSIAVTVNGLVIAFTTDVIPKSYYY--YT-RGS
LNGYMEYSLSYADTSKWDKV----------TNVNMCRFKDFRKPPCSLNHYGFSYEFWKILALKIIFVFVFERVVSSIQSLTSYIIPDVPESITMLQQRQ
RYLRRRSILETWAKENQEECIN--------------------------------------
>tr|A0A016SZT8|A0A016SZT8_9BILA Anoctamin OS=Ancylostoma ceylanicum GN=Acey_s0152.g2884 PE=3 SV=1
----------------------------------------FFSLEWD---KNCYFSDGKRQIDYVLAYEEDNNNEATSASPS------------------
----S-----------V----EKKQNRRFYFETNLQKMGLQIERVNISQLGRTRFVLLHAPFPVLEKQAQLLTVKLPVQSDGLV----------------
---DFDERVKKVL--EPDFFTAPYSSDRRKQFVNDRPDILFPHSERSRM-YDLLTRAHYDDPH----IERLVAQGVYSAAYPLHQ------GSEVSQREL
LYNHWVSWRNVLKYQPLDCIKRYFGTKIAFYFAWLGYYTRSLYLAAFVGIITVLFGFWNVG-DVVSNDICGRDSKTLICPQC-NYCDFTPLNNSCVYAKV
SYLFDNGSTVIFAALMSIWA-LFLEGWKRYHAEIAWKWGLLDFVIEE----DTVRPEFQYRVK---T----FNDESG------KKKAANFFAAMVTVVFF
MCLVLA-VFG-VVYRVICMRLLASMDNPTVD--AFLIVSATAAFINLAIIITMNYFYNSLAHRLTRWECPRTQADFDNSYTFK---FQFANYYSSLFYIA
FFKG--SQLPGH-------KRLEGCDPAGCFVELVIQLAIIMCGKQFF-SAFVEFAYPNVMSLLRKWQLMVPIVESCKKVGKDMARWEADYYLNPTQFLF
DEYLEMVLQFGFCTLFVAAFPLAPFFAVLNNILEIRLDAYKFLVNTQRPVPAQARNIGVWLKILDVISKFSVTINALVIAFTSDFVPKTMYWFAK---HS
MIGYVDSSLSYFDASEFNMK----------HNVTECRYRGWRRSPCSLDFLGLSMEWWKVFAARLLFVVVFEHVVFVIKIVVEYLIPDVPTRIFVQQQRE
KYLVRKALLNDLASGRETANGPS-------------------------------------
>tr|D2A0B2|D2A0B2_TRICA Anoctamin OS=Tribolium castaneum GN=GLEAN_07305 PE=3 SV=1
----------------------------------------VKTYKQWRDRRWRYFTNGELCVDFVLAYDKEGKPE-------------------------
------------------------VAKREHFEANLQHVGLILEKEES---QRIHFVKIHVPREVLCQYAEILKLRLPI----------------------
-VFRVRLDPKIFP--KKYRLTAEFNREKNYLFDV-DDPDFFNEAVRITV-SYILEREKFGIE-----VHRLISEGIYKAAYPLHD--------N-SKRVK
LLKHWAQVSKCVKYQPLDEVKEYFGIKFALYFAWLGFYTHMLIPASLVGILCLVYAATTL-QDTLCKDLCNS--DIIMCPRC-KVCDYWKLSEGCLYAKI
QHFVDNPATIFFAVFMSFWS-LYLELWKRYSAGITHRWGLTGFDLKA----EPPRPEYLIRLADAK-----LNNESF-----WKVKLPSIILSFTLALLW
VFIAVF-VFG-VIYRMSLITSEVLYEDK--I--RIYILPITAAIINLVCILILNIFYQRLAVWLTEMELQRTQTEYDDSLALK---FQFVNYYSSIFYIA
FLKG--VGYPAKYN------RQEECNPGGCLMELTIQLAIIMIGKQAI-NAVAEMVVPLLTKMYNSVKVSMGIQ----IGIISCNQWTEDYKLLDLQSLF
SEYLEMVLQYGFVTIFVTAFPLAPLFALINNILEMRLDAKKFIKYFRRPVPQRVTNIGVWFPIMGILGRISVVSNAFIIAFSSHFIPKLVYMMEVNP--T
EDGFLDSTLAYFDTADFED-----------MN-SICRYAEYRNPPNVTIKYKRPLIYWHILAARLAFVVAYQNLVTFVVTAVEWTIPDIPRKLNDQIKRE
AYKTNETIIKYETERARLKHRKR-------------------------------------
>tr|E4YMJ7|E4YMJ7_OIKDI Anoctamin OS=Oikopleura dioica GN=GSOID_T00029738001 PE=3 SV=1
-----------------------------------------MQNYLRCRDETLFLDGVKKKIDFIIIYSFSADSELRNHHES------------------
---------------------------RRTLKQRLRSKNLIIEDDNEEDESQKYFMKIHAPMIVLKKQAEILSINCRLQRK-------------------
---KERIEGGVLE--PEDYFTAIYRHDLHDYFAKRNEEDFFTDSQRIRM-ANMLNTIKWEGK-----IRAFLEEGAILGYYPLHD------VPKHSLRAY
LNRNWSSWKNFYRAQPLDEIRDYYGEKIALYFGFLGFYTNSLIAFSFIGFIVMIYGLATF-SDTVVTETCNMT-DVVLCPKC-FDCTFDLASDMCQPLKI
TYIFDNVFTLGYAFIISIWA-TFLELWSRKNFFLEYEWDLTKIDKDM----DPPRARYQAVASQNR-----LNKEPL------STTYPRKLLSVSVVLFF
IMLVIA-VIA-IVYRMVLSVIVNDFDFVGQV--PSILVTTTASLISLILIMGFNVIYHKAAAKLTELEVPRTQQEFDDSYSFK---FQFVNYYSNLFYIA
FFKD--VGYPTNYL------RWAGC-DGGCSYELAIQLIITMVGKQLI-NNVMEIVLPALNKWWTRKKNVDNL------GLDINARWKADSMLSSSVNYL
NDYIELAIQFGFAVLFSCAFPLAPLFAFLNNIFEIRIDAAKYVKYSQRPIPERTKNIGIWYPIFRFLAILAVITNGLQLAITSKTVPRIVYSAMGKSELP
LAGFARSIYSVYQIPDDYNG----------DN-TECHYEGYRDENLE-----PTIDYWSDRYARVLFFILYEHAVFITVWFIVWLIPNKPQSLKNMIKQE
EYIVQTILKDKAKKDLSKKNS---------------------------------------
>tr|V3ZIV9|V3ZIV9_LOTGI Anoctamin (Fragment) OS=Lottia gigantea GN=LOTGIDRAFT_108628 PE=3 SV=1
----------------------------------------------------LLFNDGKRHIDYILAWSIKGK-Q-------------------------
---------------------EEGKNARSIFEKNLRKEGLEIEYDT---GSEIHYAKVHAPYKVLIRYADILAIRMPMKHPCY---------RVSNLGKT
FLK-FLLDRD-AV---KRNYTCPYSTDKNY-FETENGELEFSNSARSRI-DYILRRKAFKDDT----VKKMINDEFYSAVYPLHE-------SAMNARKL
LYDYWAHWKNMLKFQPLDHIRRYFGEKIGMYFAWLGFYTTMLVPAAIVGFLVFIYGLFIMHASTSSKELCDPANNMTMCPLC-KQCPYWKIHEACSHQSA
SRIFDNDATVFFAVFMSLWG-LFLEFWKRKEATIQYKWDLSNFVSEE----EPPRPEYLSRLESWTTL---VNKEPF-----WRRRFPVFLCSYGVMIFL
AAVAIG-VVG-IAYRVSMLAALHILQEK-VY--AGLITTITAALINLVIILILNIVYGYLAFWLTDWECLRTQSEYDNSITLK---LQFVNYFASIVYVA
FFKG--VGRPGDYST-----RQEECEPGGCLIELCIQLAIIMVGKQLIQNNFIEIVVPKIIKMIK----KKISK-ETRAQKLAKTPWEKDYKLGSATSLF
YEYLEMVLQFGFLTIFCSAFPLAPLFALLNNVIEIRVDANKLITGLRRPMAERAADIGIWYSVLYGISRIAVISNAFIISLTSDFIPRLVYKMAYSE-KT
SQGYLNHSLAIFNTSHFSMSHMP-----DPGHVELCRYRDFRNPPDHKDAYAFSDVFWHNLAARLAFVVVFENVVIVVTSLIAWMIPDVPTILKEQIRRE
AYITNEVVLKTELLRARGETIDA-------------------------------------
>tr|A0A0Q3Z4Z9|A0A0Q3Z4Z9_ALLMI Uncharacterized protein OS=Alligator mississippiensis GN=Y1Q_031077 PE=4 SV=1
----------------------------------------AELVEFDRKPDSLFFNDGQRRIDFVLVYEDESKKENRTKK--------------------
---------------------KRKQRKRENYESNLISNGLELEATRS-LDEHLIFVKVHAPWEVLCTYAEVMHIKLPLQND-------------------
---LFRVDENII---EQEFFTAPFEKD----FYIQDKDMFFNPATRSRI-YFILSRVEYEVR-----INKLLDSGIYKAAFPLHD----KSPNCPSERYL
LYKEWAHPRKIFKLQPLDFVRKYYGEKIGIYFAWLGFYTQMLLLAAVVGLGCFLYGCITKD---C-QEVCDPNGNIIMCPQCDRECTYWNLTITCESSKK
LCMFDSFGTLVFAVFMGIWV-LFLEFWKRRQAELEYEWDTVEFL--E-------RPEYEARC---------MNEEPYT---AC--KCVRM-CCTSAVFFW
ILLIIA-VIG-IVYRLSVFLVFSSTPRHI----PQTATSVTASIISFIIIMILNIIYEKVAIMITDY--PRTQTDYENSLTMK---FQFVNYYSSCFYIA
FFKG--VGYPGDPVYWLGKY-NEECDPGGCLLELTTQLAIIVGGKSIW-NNVQEVLLPWIKNLIGRC-------CAARSEKV-IPRWEQDYHLQPILGLF
YEYLEMVIQFGFVTLFVASFPLAPLLALINNLLEIRIDAWKITTQFRRMVPQKAQDIGAWQPIMQGMAILAVVTNAMIIAFTSDMIPRLVYYPPYGN-YT
MKGYINNTLSVFAVSDFRKESK--PVPLS--------YRDFRYPPGHEHQYEHNTYYWHVIAAKLAFIIVMEHIIYFVKFIISYAIPDVSKKTKSKIKRE
KYLTQKLLHENHIRVMKKNVGNI-------------------------------------
>tr|M7B488|M7B488_CHEMY Anoctamin (Fragment) OS=Chelonia mydas GN=UY3_10947 PE=3 SV=1
--------------------------------------------EFDQKPDSLFFNDGQRRIDFVLVYEDENKNENRKKS--------------------
---------------------KQ-MRKRRAYESNLISNGLQLEATRS-LDEKLIFVKVHAPWEVLCTYAEVMHIKLPLKND-------------------
---LFRVDENII---EQEFFTAPFEKA----FYIQDKDIFFNPATRSRI-HFILSRVEYAVR-----INKLLDSGIYKAAFPLHD----RSPNCPNERYL
LYKEWAHPRSIYKLQPLDLVRKYYGEKTGIYFAWLGFYTQMLSVAAVVGLACFLYGYITKD---C-QEVCDPNGNIIMCPQCDQECTYWNLTITCESSKK
LCIFDSFGTLIFAVFMGVWV-LFLEFWKRRQAELEYEWDTVEFL--E-------RPEYEARC---------TNQEPYT---AC--KCVRI-FCISAVFFW
ILLIIA-VIG-IVYRLSVFLVFSAKPRHI----PQAATSVTASIISFIIIMILNIIYEKVAIMITDF--PRTQTDYENSLTMK---FQFVNYYSSCFYIA
FFKG--VRFPGDPVYWLGKY-NEECDPGGCLLELTTQLTIIMGGKAIW-NNIQEVLLPWVKNLIGRC-------CAARSEKT-IPRWEQDYHLQPVLGLF
YEYLEMVIQFGFVTLFVASFPLAPLLALVNNLLEIRVDAWKITTQFRRMVPQKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYPPYGD-YT
MKGYINNTLSVFNISDFKNESK--PVPLP-------VYRDFRYPPGHQYQYEHNIYYWHVIAAKLSFIIVMEHVIYCVKFIVSYVIPDVSQKTKSKIKRE
KYLTQTLLHENHLKVVEKKMGKI-------------------------------------
>tr|F6YYR5|F6YYR5_XENTR Anoctamin (Fragment) OS=Xenopus tropicalis GN=ano6 PE=3 SV=1
----------------------------------------AEIVEFDENLDSLYFTDNQRRIDYVLVYEDETMKEHIAKK--------------------
---------------------KQ-KKKRQAYESNLIKSGLHLEATRS-SDGKIIFVKVHAPWEVLCTYAEVMHIKLPLQND-------------------
---IFRVSEDII---EQEFFTAPFEKD----FYIQDKETFFTPATRSRI-HFILSRVEYAIK-----INKLLDSGIYKAAFPLHD----VSSRCPSERYI
LYKQWAHPFSILKFQPLDLVRKYYGEKVGIYFAWLGFYTRMLIVAAVVGVACFLYGVKSQE---C-KEVCDPSGSIIMCPQCDKACNYWYLNITCESSKK
LCIFDSFGTLVFAVFMGIWV-LFLEFWKRRQAELEYEWDTVEFL--E-------LPEYEAKC---------KNQEPYT---AF--KCLRV-CCTSAVFFW
ILLIVA-VVG-IVYRLSVFLVFSATPRAVVE--PQTATTITASIISFIIIMLLNMLYEKVAIIITDF--PRTRTEYENSLTTK---FQFVNYYSSCFYIA
FFKG--VGYPGDPVYWFGKY-NEECDPGGCLLELTTQLTIIMGGKAIW-NNIQEILVPWVKNLISRC-------R-SGSKAV-LPRWEADYLLQPALGLF
YEYLEMVIQFGFVTLFVASFPLAPVLALVNNLLEIRVDAWKITTQWRRMVPEKAQDIGAWQPIMEGVAILAVVTNAMIIAFTSDMIPRLVYYPPYGN-NT
MQGYINNTLSVFSVSDFQSESK--PVAVN--------YRDFRYPPGHEHQYEHSVYYWHVVAAKLSFLIVMEHIVYFVKFIIAYIIPDVSNETKDKIKRE
KYLTQKLLHERHLRVMKKQMGGL-------------------------------------
>tr|G1KAT6|G1KAT6_ANOCA Anoctamin OS=Anolis carolinensis GN=ANO6 PE=3 SV=2
----------------------------------------PEWAEFNLQPDSLYFNDGQRRIDFVLVYEDENKKEGHKKS--------------------
---------------------KQ-MRKRQAYQSNLISRALQLEATRT-LDEKCIFVKVHVPWEVLCKYAEIMHIRLPLQSD-------------------
---FFSVDKEII---EQDFFTAPFEND----FYIQDKDTFFTPATRSRI-YFILCRGEYAIR-----INKLLDSGIYKAAFPLHD----QSPTCPNERYL
LYREWAHPRNILKLQPLDLVRKYYGEKIGIYFAWLGFYTQMLLLAAIVGLGCFLYGYFTRD---C-QEVCDPNGNIIMCPQCDQECTYWNLTITCESSKK
LCIFDSFGTLVFAVFMGIWV-LFLEFWKRRQAELEYEWDTVEFL--E-------RPEYEARC---------VNQEPYT---TC--KCMRM-FCTSAVLFW
ILLIVA-VIG-IVYRLSVFLVFSATPRHI----PQAATSVSASIISFIIIMILNMVYEKVAIMITDF--PRTQTEYENSLTTK---FQFVNYYSSCFYIA
FFKG--VGYPGDPVYWLGKY-NEECDPGGCLLELTTQLTIIMGGKAIW-NNIQEVLLPWLKNLIGRC-------CANRSEKI-LPRWEEDYHLQSILGLF
YEYLEMVIQFGFVTLFVASFPLAPLLALINNLLEIRVDAWKITTQFRRMVPEKAQGIGAWQPIMQGIALLAVVTNAMIIAFTSDMIPRLVYYPPYGN-YT
MKGYINNTLSVFAVSDFRNESK--PAFHP--------YRDFRYPPGHEYQYHHNIYYWHVIAAKLSFIIVMEHIIYFVKFAISYIIPDVSKETKSKIKRE
KYLTQMLLHENPLKSVKKNIGSI-------------------------------------
>tr|E5S756|E5S756_TRISP Anoctamin OS=Trichinella spiralis GN=Tsp_10982 PE=3 SV=1
----------------------------------------SIGS----IGSRKSDGQKPNLADFVLVYEKQPNV--------------------------
---------------------DKLMAQRCFFEQNLRTEGLQLEVES--PSSRVCFVKIYAPFGLLCRRAQRLQMKLPVRAV---QQVLP--NE----LQR
SKKFTIDEE------PTLHITAPFIQS-LDLYNA-EEEKLFSTNQRSRI-FDLLQRTRCD-------IGWMLSIGAYKAAYPPHD-----------TRQI
LRLTWANFSCMLKPQPLQLIRSYFGEKIAFYFAWLGYYTAWLTLPGLFGLICFVCS-LSWTSSDHLAEICNSNGNLTMCPVCIENCVPWKLASSCESAIW
NYTFDNYAGILMAVVTLTWA-FFLETWKRREASLAFQWDAFDVEEYS----EGLRPEYETEIHRLNSS---STQEPLLKS----A-------SLSGVLLL
-GAVLL-LVA-IVIRIEIYGL-LKKI---WFAYQYEVTSMIIHLCTFAVVMTLGLIYEQSAHRLTDFECPRTQTDYLNSYIWK---FELLNNFGPIFYAA
LIRG--FSLPNEQTH---------CDPGGCLNEPVQAIAILLLARLLI-SNAAELGYPLMKKVLKGRRLVTSEVVEGANGGRNQPTWRKDFALNEPDGVY
AEYLEMMVQFGYVTLFVSIFPLAPMICLLNNIVEVRLDAINFVVSYRRPVPIRVAGIDTWHRCLNIILKLAIICNGAVLAFTSEILPKVIHNFYFQQD-Q
NESYLEFTLISFNTTSWPQYKTY-------EENQICYYRD---------MYQHTVKGQQITIARLVFI-AFVMFFYLLHWLVHTLLPKIPSDISNSMRRA
NLIAREVFYGKDVDLGSLEYSSG-------------------------------------
>tr|A0A0N5DJY3|A0A0N5DJY3_TRIMR Anoctamin OS=Trichuris muris PE=3 SV=1
----------------------------------------TLRQ-----KQLDLESLRHRLPDFVLVYDKTQGG--------------------------
----------------------DLKRCRDYFEQNLTREGLLLDLDT--DSTKLCYVKVYAPFALLCHRAQRLQMKVPMQQL----------------LKR
SKSLTNLEQ------HPVQVSAPFVHS-LDLYHW-DEDCFFTINQRIRM-HDLLIRARCD-------MQWLLKTGAYKAVYPPHD-----------VRQV
LRYTWANFASALKPQPLNLVQSYFGEKIAFYFAWLGYYTCMLTIPGIAGLLCFVYT-MSQLGSDHLEQICSHNATITMCPVCVENCVPWTLEQSCDSAKW
NYTFDSKANIAMTIVTLVWA-LFLETWKRREATLAYTWNAYDAEQVS----GAVRPEYEAESHRVTEC---SDHEPLCKR----G-------SAAGVLLL
-LMVLM-MIA-IAIRIEIYGL-LKGF---WLVYQFEVTSMVIHLCTFVVVMTLGVLYERSAHRLTEFECPRTETAYLNSYVWK---FELLNNFGPIFYAA
LIRG--FSLPSDQTH---------CDPGGCLNEPVQAIAILLLARLLI-SNAAELGYPLLKKVLKGRRLGTSEVVDSGGSGRYQPQWRKDFTLNDLDGVY
TEYLEMMVQFGYVTLFVSLFPLAPLICLLNNIVEVRLDAINFVLSYRRPVPYRVSGIDTWNTCLSIILKLAIVCNSAVLAFTSETIPRVMHRTLFNDS-S
SGSYLNFTLVPFNTSSWPGYKEL-------DAPSICYYRD---------TYQNTLEWQTVTIARLVFI-TLVMFFYVIHWFIQTLLPKLPSDVRNSMQQA
NTIAREAFYGKELAVGVVDHSAH-------------------------------------
>tr|E5SY63|E5SY63_TRISP Anoctamin OS=Trichinella spiralis GN=Tsp_10873 PE=3 SV=1
----------------------------------------SGAH----FSDGTCFGDGHRRIDFVFTFKKSSKH--------------------------
-----------------------HTERRQFFEQNLIAEGFHLEYQE--HKDYMCFVLVHVPDDVLLRYAEMWKVKLPVPGE---TRN----------TER
IKYAILNDH------AKHHFLWPYNSE-KECFDL-AESCFLTEAQRQAI-WQVLQGIQND-------IEMLLRIKVYDHAYPLND-----------VRKF
LSDNWASHRQMFNKQPLHHIYRYYGHKVSYYFAFMGFYTRMLIPAAIAGIIATLFG-LLNMDNDVADEVCDAEGNLTMCPICEPNCELWELAEGCMRTKL
SYVMDNEATLLMSCFIIVWE-VLVKLWKRREAALAFEWGTDDLEESD----EIIRPDYLVHAHKERL------DKEMEPCGNLSI-------SLSITLLM
-VSSSA-LVG-SLLRVLLYGE-FRKL---FKKYSIDFARWTVHGFIFIAVFVYEKIYDLICHRLTTMERPRTEKDYWFSFLWK---FELLNEFIPIFYVA
FFKE--INTPLDLHG---------CDPGGCTSEVTELISVLLLARLIV-KNVIGSGLVWMRHMLDRCKSIYVHK-----VDNNYPQWRKDFYLEELDGVA
EEFMEMIIQFAFCTLFVVAFPLAPLLCFINNLIELRMDAKKM-VHHRRPVPVRVSGIEIWNTFFEWIVQISVLTNAAFISFSSDLIPKLYYRSKYSPDNT
FLGFANFSLSRVFTYEWIKYSEE-------NVT-ECWYKGYRSR---YPPYNVKPQWWEITAVRLGFT-ILVCAFYVFTFIVNKAINDRPEWTCTNETRE
NYNVTAALVPQQMIEALMRAYSE-------------------------------------
>tr|W5LEW6|W5LEW6_ASTMX Anoctamin OS=Astyanax mexicanus PE=3 SV=1
-----------------------------------------ARGNNPAIPSGLTFRDGKKRIDYILVYKKSSPQ--------------------------
------------------------VEKRCTFERNLRAEGLMLEKE---TNNDIMFVKIHAPWDTLCKYAEQMNIRMPFRKK--------TLGS-----R-
FHLPMKLDKEALP--ESDCYTAPFSRA----FTINNRDSFFSNSTRSRI-HHVLQRTKYEDG-----INRLLGNGTYEAAFPPHE----RHHGAQNHRHL
LYERWARWGIWYKYQPLDLI-RYFGEKIGLYFAWLGWYTGMLIPAALVGLFVFLYGLFTMD---SSKEICEA-NTTIMCPMCEVNCSAWKLSDSCVYAKV
THLFDNGGTVFFAIFMAIWA-VFLEFWKRRRAELTYDWDLIDWEEEE-------RPQFEA------KY---VNPEPFT-------KLSRL-VSVSGIFFM
VGHRIQ-SEI-MIHDLIVIEQQ-AFYYIY-Y--DF-ELKNTRTCTRGVILIIIKINKKKVYFLLETY--PQRTRKIGFSRKVT---FFFIFVKGVFFKLI
FQVG--NSKNS-----LRHCKIIVCSSYNFFIDICLNMNIVVLFYKLY-SRCFKGKIKLLQNWWSRRKMRRAG--NNVECKEKMPQWDKDWNLQPMHGLV
D--LEM-LQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPMPARATDIGIWHGILEGIGVVAVITNAFVIAITSDYIPRFVYAFKYGP-QC
LRGYMNSSLSVFDMGEPQNESQY-Q-------TRYCRYRDYRAPPWSSEPYEFTLQFWHVLAARLAFIIVFEHLVFGIKTFIAHLIPDMPKDLCERMRRE
KYLMQEMMYEAELEHLQKERK---------------------------------------
>tr|Q16MH3|Q16MH3_AEDAE Anoctamin OS=Aedes aegypti GN=AAEL012300 PE=3 SV=1
----------------------------------------GSIFAIGSTKRNLKFKDGIRTVDFVLTRNPDHA---------------------------
----------------------DKQVRRCYFEKNLTEEGLQIEPDDFEDSKKARFTKIHVPQETLLRYCEIMRIKMKVNSGADG-N-NV----RVSL---
-TGFLNLNE------EGNPILYEYSRGKDYLFGK-NVAMSVAPTVRTAV-HYIMERTNCGDKK----LTKLLEEGVYLDAFPLHD--------EECKRTW
LLQEWASMVHWIKLQPLTEVKDYFGTHVGMYFAWQGFYTNMLIWASSAGMLCFLFGLVTF-SNQVSQDICRD-NSTIMCPQC-AICDYWKLGDTCLSSRL
AYLFDNKLTIWFALFMSVWA-VYLKMWKRYVSHLQHKWGVRDYDAQV----EPPRPQYLARLLERNSKITNLNKERF-----WSTKLPSLLYSYSVILLF
IGLAVA-VFG-VIYRMSLLTARHIYGDPADV--KRLMFSAVAAIIDLALSIALDVAYNAVAVRMTNIEYHRTQNDYNESLNLK---FQFVNYYSSIFYIA
FLKG--PGYPAKYN------RQEECQPGGCLMELSVQLAIIMIGKQTV-SLIRDFSIPYFVKQYREWRKRNSKE----DDSVDSNEYTEDDSLISWRCRY
DDYVKMVIQYGFITIFVVAFPLAPLFALLNNVFETRLDAMKYLKFYKRPVPKRVRDIGMWYDIMDVIAKMAVVSSAFIIAFSSTFIPRLVYMSVVNR--T
DEGFLNHTLAYFNVEHFQAG----------HN-SMCRYQEYRNPPFG-RPYKRPLIYWHIFAFRLAFIVIYQNVVSTVQGLVNWIIPDTPSRLQEQIKQE
QYYINQRIMSGERAKAKRTVKSL-------------------------------------
>tr|F1NTF5|F1NTF5_CHICK Anoctamin (Fragment) OS=Gallus gallus GN=ANO2 PE=3 SV=2
----------------------------------------Q-GEAM-DSMSGMHFRDSNRKVDYL-VYHYRKRLTQHQPGAGS-----------------
-PRPMHRAA---SMAIVS--NEEKRLQREEYECNLVAAGLEIEKDTE-KSQGLNFVRIHATWQVLSREAELLKIKMPTKK-YEIKEEGGIVKKLSEIWRK
LSEPLQPQVPQ--EDKMKSLSYPFSREKIYLYNIRDKDTFFDNATRSRIVHEILKRTS-TKTRNSM-ISTLIANNVYDAAYPLHDGEYEY-NDDMNERKL
LYREWARYGVFYKFQPIDLIRKYFGEKIGLYFAWLGLYTEFLIPSSVVGIIVFLYGCITIESDIPSKEMCDQRNSFTMCPLCDKFCDYWNLSSACSTARA
SHLFDNPATVFFSIFMALWEATFLEQWKRLQMRLSYFWDLTGLEEEEEEKQEHPRPEYETKLLQKKLKNKNNEPEDGEDKLTWNDRMPGYAVNFGLILFM
ITLTFSAVFGVIVYRITTSAALSLSTNETTRSNVRVTVTATAVIINLVVILILDEIYGAV-KWLTEIEVPKTEKTFEERLILKAFLLKFVNSYAPIFYVA
FFKG-FVGRPGHYVYVFDGYRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKLKKLFRKMKDERTE-KMDTNQPKDPQQWDLDYSLEPFTGLT
PEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEVRLDAKKFVTELRRPDTVRAKDIGIWYNILSGIGKLSVIINAFVIAVTSDFIPRLMYQYAYSQNGS
MHGFINHTLSYFNVSHLKAGTQPENSPFA-QDILFCRFKDYREPPWSQNQYEFSKQYWAVLSARLAFVIIFQNLVMFLSVLVDWMIPDIPKDISEQIKKE
KSVLVDFFLTEERKKLKLIESFI-------------------------------------
>tr|G1NM98|G1NM98_MELGA Anoctamin (Fragment) OS=Meleagris gallopavo GN=ANO2 PE=3 SV=2
----------------------------------------QGEAMDS--MSGMHFRDSNRKVDYVLVYHYRKRLTQHNPGAGS-----------------
-PGPMHRAA---SMAIVS--NEEKRLQREEYESNLMAAGLEIEKDIE-KSQGLNFVRIHATWQVLSREAELLKIKMPTKKMYEIKEEEGIVKKLSEIWCK
LSEPLQPQVPQEDS-KMKSLSYPFSREKYFLFSLQWVSKFHSTAPSMRKVHEILKRT-STKTRNSM-ISTLIANNVYDAAYPLHDGEYE--NDDMNERKL
LYREWARYGVFYKFQPIDLIRKYFGEKIGLYFAWLGLYTEFLIPSSVIGIIVFLYGCITIESDIPSKEMCDQHNTFTMCPLCDKFCDYWNLSSACSTAQA
SHLFDNPATVFFSIFMALWGDLFVKKWKRLQMRLSYFWDLTGLEEEEEIKQEHPRPEYETKLLQKKLKNKNNE-KDGEDKLTWNDRMPGYAANFGLMLFM
ITLTFSAVFGVIVYRITTSAALLFSTSETTRSNVRVTVTATAVIINLIVILILDEIYGAVAKWLTEIEMPKTEKTFEERLILKAFLLKFVNSYAPIFYVA
FFKG-FVGRPGHYVYVFDGYRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKLKKLFRKMKDERTE-KMDTNQPKDPQQWDLDYSLEPFTGLT
PEYMEMIFSFLFIYLFIYLFIYLFIYAWLKNFFLEELKRKKISTQLRRKMPYGTTFTGIWYNILSCIGKLSVIINAFVIAVTSDFIPRLMYQYAYSQNGS
MHGFINHTLSYFNVSHLKAGTQPENSPFA-QDILFCRFKDYREPPWSQNQYEFSKQYWAVLSARLAFVILFQNLVMFLSILVDWMIPDIPKDISEQIKKE
KSVLVDFFLKEEHKKLKLIESFI-------------------------------------
>sp|Q6IFT6|ANO7_RAT Anoctamin-7 OS=Rattus norvegicus GN=Ano7 PE=2 SV=1
--------------------------------------------QQVAPSR--VGSSANPPIDFVLVWEEDLRS---RENPT------------------
---------------------DTHEIWRETFLENLRVAGLKIDQ----EAAAVHYILLSAPWAVLCYYAEDLRLKLPLQ---------------------
---WL-----GIP--PPEYYSCQFKASKLQWFLGDNQDTFFTSTKRHQI-FEILAKTP---------IDQLLAEGVFSAAFPLHDVPES--VLGLTQRQV
LFKHWARWGKWRKYQPLDHVRRYFGEKVALYFAWLGFYTGWLLPAAVVGTVVFLAGCFLVFSDVPTQELCHSSDTFDMCPLC--DCSFWLLSSACTLAQA
GRLFDHGGTVFFSLFMALWA-LLLEYWKRKNATLAYRWDCSDYEDIE----ERPRPQFAATAPM-------LNDEPE------KNRVRRMLAGSVVLLMM
VAVVIM-LVS-ILYRAVMAIIVSKS--NALS--ASRIASLTGSVVNLVFILILSKVYVILAQVLTRWEMHRTQTAFEDAFTLK---FQFVNFYASPVYIA
FFKG--VGYPGNYH------RNEE-PAGGCLSELAQELLVIMVGKQII-NNVQEVLVPKLKGCWQKLCSRRKKA---G-MGANPAPWEADYELLPC-GLF
HEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARKFVCEYRRPVAERAQDIGIWFHILAGLTHLAVISNAFLLAFSSDFLPRVYYSWTRA----
LRGFLNFTLARA-----PPTFTSAH-------NRTCRYRAFRDDDGH-----YSPTYWTLLAIRLAFVIVFEHVVFSTGRFLDLLVPDIPESVEIKVKRE
YYLAKQALADNEALLGATGVKGE-------------------------------------
>tr|F7CRW6|F7CRW6_HORSE Anoctamin OS=Equus caballus GN=ANO7 PE=3 SV=1
--------------------------------------------HQAAACR--VGSPAKPRIDFVLVWEEDLKPGQQQDNTT------------------
---------------------DMHGDWRETFLDNLRAAGLCVDQ----ADSAVHYVLLSAPWAVLCYYAEELRLKLPLQ---------------------
---WL-----GIP--PPEYYSCQFKVSKLSRFLGDNQDTFFSNTQRHQI-FEILAKTP---------IDQLLSEGVFSAAFPLHDPPEG--APGLNQRQV
LSQHWARWRKWNKYQPLDHVRRYFGEKVALYFAWLGFYTGWLLPAAAVGTLVFLVGCSMLFSDTPTQELCSSADSFEMCPLC--DCPFWLLSSICALVQA
GRLFDHGGTVFFSLFMALWA-LFLEYWKRKSATLAYRWGCSDYEDVE----ERPRPQFAASAPT-------LNDEPE------RSRLHRVLAGSVVVVMM
VAVVVM-LVS-ILYRAIMAILVSKS--NTLA--ASRIASLTGSVVNLIFILILSKIYVALAHVLTRWEMHRTQTKFEDAFTLK---FQFVNFYSSPIYIA
FFKG--VGYPGNYH------RNEE-AAGGCLIELAQELLVIMVGKQII-NNVQEILVPKLKGWWQKVRLRSRKR---A-VAAGRAPWEADYELLPC-GLF
DEYLEMVLQFGFVTIFVAACPLAPLFRGSSQIICARGPSLPFLPREPRALWDRTESILYFFSLYAHLELMAFVNHICLVYFTNFLLPRSFRSRLL-----
--EVPSCCSFSISPQ--PPGTYSAI-------PISCRYQAFRDDDGQ-----YSRTYWNLLAIRLAFVIVFEHVVFSIGRVLDLLVPDIPESVEIKVKRE
YYLAKQALAENEALFGAGGAKDN-------------------------------------
>tr|M3WDA7|M3WDA7_FELCA Anoctamin (Fragment) OS=Felis catus GN=ANO7 PE=3 SV=1
--------------------------------------------HREAAGR--VGSPSKPRVDFVLVWEEDLRLGRQQGGAS------------------
---------------------DTRGAWRETFLDNLRAAGLHVDQ----ENGAVHYVLLRAPWAVLCYYAEDLRLKLPLQ---------------------
---WL-----GLP--PPEYYSCPFKVSKLSRFLGDNQENFFTSTERHQI-FAILAKTP---------IDQLLAEGVFSAAFPLHDPPEG--APGLTQRQV
LFRYWARWSQWNKYQPLDHVRRYFGEKVAFYFAWLGFYTGWLLPAAAVGTLVFLAGCFLVFSDIPTQELCSGADHFEMCPLC--DCPFWLLSSACTLVQA
GRLFDHGGTVFFSVFMALWA-LLLEYWKRQSATLAYRWGCSDYEDIE----ERPRPQFAASAPT-------PNDEPE------RSRVRRVLAGSTVVVMM
VSGWSM-LVS-ILYRAIMAILVSRS--NTLA--ASRVASFTGSVVNLVFILVLSKIYVALAHILTRWEMHRTQTKFEDAFTLK---FQFVNFYSSPIYIA
FFKG--VGYPGNYH------RNEE-AAGGCLIELAQELLVIMVGKQII-NNVQEILVPKLQGWWQKFRLRSKKR---S-EAVGQAPWEADYELLPC-GLF
DEYLEMVLQFGFVAIFVAACPLAPLFALLNNWVEIRLDARKFVCEHRRPVAERARPTWFWQFHLQKTYSTMIC-LSSVLVVTSFSFPIVFFPLKNF----
YRGFLRFFRNTPSSR--HSQASQAQ-------NYTIRYQAFREDDGQ-----YSATYWNLLAIRLAFVIVFEHVVFSIGRILDLLVPDIPESVEVKVKRE
YYLAKQALAENEALSGTNGAKDN-------------------------------------
>tr|T1FWX8|T1FWX8_HELRO Anoctamin OS=Helobdella robusta GN=HELRODRAFT_62245 PE=3 SV=1
----------------------------------------------------VFFNDGVRRIDYILVWSSNKARD-------------------------
---------------------ATKESFRKTFVNNLIEEGLHVEEDI--ESRNVQFAKVHAPFEVLARHTDNMKLKMPIKVSWG---------RMTGCFKK
FLS-FELDPY-RV---TKKFTCTFQKEKMY-YDVTPKENFFSRATRCRI-DFILRRTEYGHEH----IKNLIANGTYLSAYPLHE-------SRMSIRKL
LHDNWASSSVWFKVQPLDYIRSYFGEKIGFYFAWLGYYTYALIPASIVGLLVFIYGLVYINSDPIAKDSCE-KNMFIMCPKC-KRCSFWGYHRMCYYILV
THLFDNAATVFFAAFMSLWG-IFLEFWKREQASIQYLWDLKNFEEEE----EPPRPEYLVKISESKYT---KNKEPF-----WKRKMPVYLTSASVMFFL
ILVAIA-VLG-TAYRIAILSVMYTNDH--VY--APLIGSISAAIINLILIFILNFVYEKLAIKLTDWECLRTQHDYDNSLRYK---LQFVNFYSSLFYIA
FIKG--NGPPNERSK-----RLEECDGGSCLTELCIQLAIIFVGKQLIQNNLVEIVLPFVSRIKRA-IRMCLRN-KNK--KLILKPWEKDFNLEEMLGLL
QEYLEMMIQFGFVTLFVAAFPLAPCFAFINNLIEIRSDANKFVTQYRRPMPARAVSIGVWYEILHAITRISIVTNACIIAFTSSFIQRELYKRVYSS-NT
LNGFLNNSLAYFDVNDFVNGTAPKTEDIKEKNTTYCRYLDYREPPWSAKKYQYTTQYWHLMASQFIFVVLFENIIVLITCFVAYLIPDTSTQVSHMMRRE
AVVVNEILLKTELNRAKGFKPGL-------------------------------------
>tr|K7IMJ8|K7IMJ8_NASVI Anoctamin OS=Nasonia vitripennis PE=3 SV=1
----------------------------------------NSGFSYYDAASSLYFRDGIRPIDFVIVWDEFNH-E-------------------------
---------------------YRCKEMRKTFENNLENEGLNLEYEC--EPNGLCFIKISTPREVLRRYSEILKLRMPMKI-QE---------VNS-FFRQ
IMS-YYVNSA-IF---RHKFTAVYSRDKEY-FDT--SPDFFTPATRSRI-QFILDRTRFTIDK----IERLINEKAYTAAYPLHD------T-PDSMRYL
LYTEWASVNKCLNYQPLDYIKEYFGVKIGLYFAWLGFYTHMLLPASVVGLICFAYSLFTLYSNEPSKDVCMSN--YTMCSLC-HFCGTWNLRDTCFHSKV
TYLFDNPSTVFFAVFMSLWA-LFLELWKNYSAEITHRWDLTSLDIHE----EHPRPKYLARLAHVKKK---VNVEPF-----WKVRLPATIFSCSVILLL
IAVAMA-VLG-VLYRMSVLTALYGFSNN-VT--AILLTTATAAGINLCCIVVFNWIYVWFAEYLTEIELPRTQTEFDDSLTLK---LEFVNYYASIFYIA
FFKG--IGYPGKYNR-----RQEECGPGGCFLELCIQLGIIMIGKQAV-NSILEMLFPLFYKWLNT-IRVHVGLGQ-KNLSRMHLQWVRDYKLVQWRSLF
PEYLEMVLQYGFVTIFVAAFPLAPFFALVNNVLEMRLDAKKLLTMYRRPVSQRVRDIGIWYRILDSISKLSVITNAFIIAFTSNFIPRLVYRIVVSE-HT
LKGFLENSLAKFNTSDDP----------FNEESTICRYPDYREPPDSPKKYQYTDLFWHILAARLAFVVVFENIVALVIIIVRWCIPDMSPRLRDKIRRE
AYITNEIIIQHEAQRACKLPVDE-------------------------------------
>tr|A0A087YMM3|A0A087YMM3_POEFO Anoctamin OS=Poecilia formosa GN=ANO2 (2 of 2) PE=3 SV=2
--------------------------------------------------------DGKRKVDYILCYKYKKRRS-------------------------
--C-KRL-------SISS--NEEKALMREEFEAGLLEAGLQIERDKEDKLNGISFIRLHIPWSILSREAELQKIKVAVKKKCELRKRTGIAGMWDTVISQ
LNRPFQPDVPDNDIHNFKTLKHSFIRDKLHLYDIKSTATLFDNATRSRIVAEIISRTTCTRTCQTT-ISSLLARGVYISAFPLHDGPFTRRKDQRNERQL
LHEEWANYGVMFKYQPVDLIRKYFGEQIGLYFAWLGVYTQLLIPPSVLGIIVFLYGILTVDTNVPSQETCDDNLNITMCPLCDAVCDYWRLSSVCSLARA
SYLFDNGATVLFAIFMSLWAACFLEHWKRRQMCLKHSWDLTSLEHEEERVQDELRPEYAEALQEKKAKLKAN--------LTYLKFFNLYFTVSLGLCFT
IFVTFSAVFGVVVYRICMLSVWSMNPDPEAKASVRMTVTTTGIILNMLVVLVLEEVYGAIAVWLTELELPKTEEEFEERLIFKSFFLKSMNAFAPIFYVA
FFKG-FAGRPGDYVYVFGDYRMEECAPPGCLIELCIQLSMIMLGKQLIQNNVFEILIPKMKKMYRTIQEEKGKKENETEEIRPKQQFDKDFALEPFEGVS
PEYMEMIIQYGFVSLFVASFPLAPAFALLNNVIEIRLDAAKFVTEIRRPDAVRCKDIGIWYNILCGISKFSVITNAFVISFTSEFVPRMVYQYMYSGNGT
MSGYTEHSLSYFNVSNFPPGTAPTTTLIT-GVSMCRRYKDYRDPPWASDAYTFSKQYWSVLAARLAFVIFFQNLAMFLSMLVAWMIPDVPRSLREQLKKE
NMALMEFLLGQDQ-----------------------------------------------
>tr|W5K9D4|W5K9D4_ASTMX Anoctamin OS=Astyanax mexicanus GN=ANO2 (1 of 2) PE=3 SV=1
----------------------------------------A-----PCPREGLCFADGRRRVDYVLVYHCKKRHS-------------------------
---QSHH-------SIVS--NVEKALIREEFERGLQEEGLEIERDKG--MKTVRFTRLHVPWSVLSREAELLKIKVPTKRTYELKEKTGLAGAISSFWEK
LNQPFQPGVPELVNP-TRVLSLPFNREKLHLFDIKSKNTLFDNATRGRIVLEILRRTACTQTFYN--ITSLLAKGVYDSAFPLHDGDFNSSKENRNDRQL
LHEEWANYGVCFKYQPADLIRKYFGEQIGLYFTWLGVYTQLLIPASAMGIAVFIYGWLTVDTNVPSQEMCDKRLNFTMCPLCDSVCDYWQLSSMCSTARA
SYLFDNHATVAFAIFMSLWAAVFLEHWKRRQRCLQHRWDLTGIDEEEIYAKDELRPAYEDFLLQKREKKNK----FASESLTWKDRLPGYCINVSSILLM
VGVTFSAVFGVILYRIIVFAVMSMNPDHEAKANVRVTVTTTAVIINLLVVLVLDEIYGAVAVWITELEIPRTEAAFEEHLILKAFLLKSMNAFAPVFYVA
FFKG-FAGRPGDYVYVFQDFRMEECAPAGCLIEVCIQLGMIMLGKQLIQNNVFEIAIPKLKKMYRTYKEEKEGGKKDKDPNRPRHRWDLDYELEPYEGLS
PEYMEMIIQYGFVTLFVASFPLAPLFALLNNVIEIRLDAAKFVTEIRRPDAVREKEIGIWHNILSGISKFAVITNAFVISFTSEFIPRMVYQYLYSETGT
MHGFTDHTLAYFNTSNFKPGTAPNSTRFD-RELRICRYKDYRDPPWSPESYQLSKQYWSVLAARLAFVIFFQNLAMFLSMLVAWLIPNVPRSLKERMKHD
KALLMDLLLSEEAEKQRRQSQRP-------------------------------------
>tr|E7F3A3|E7F3A3_DANRE Anoctamin OS=Danio rerio GN=si:ch73-86n2.1 PE=3 SV=2
----------------------------------------G-----PGPGGGLCFADGHRRVDYVLVYHCKKRQA-------------------------
---HHRH-------SVVS--NGLKDKIREEFERGLQEEGLEIEQDKELKMRTVRFTRLHVPWSVLSREAELLKLRVPTKKTYQLKEKTGLMGVMSSFWMK
INQPFQPGVPEPQNP-TRVLSQPFSRDKLHLLDIKSENSLFSNAIRGRIVYEILRRTACTQSCQT--ISSLLAKGVYDSAFPLHDGDFDSSKEHRNDRQM
LHEEWANYGAFYKYQPMDLIRKYFGEKIGLYFAWLGVYTQLLIPASALGVAVFLYGCLTVDTNVPSQEMCDERLNFTMCPLCDRVCDYWQLSSICSTARA
SYLFDNHATVGFAIFMSLWAAVFLEHWKRRQRCLQHSWDLTGMEDDE----NELRPAYEDFLHKKQEKKAKA-GGLASESLSWTDRLPGFCINISSILLM
VGVTFSAVSGVILYRIIVSAVMSMNPDHEAKANVRVIVTTTAVIINLLVVLVLDEIYGAIAAWITELEIPKTEATFEEHVILKAFLLKSMNAFAPVFYVA
FFKG-FAGRPGDYVYVFKDFRMEECSPGGCLIEVCIQLGIIMLGKQLIQNNVFEIAIPKLKKMYRTYKEEKDGSDDDKDSKREPQRWDLDYDLEPYEGLS
PEYMEMVIQYGFVTLFVASFPLAPVFALLNNVIEIRLDAAKFVTEIRRPDAVSAKEIGIWYNILSGISKFAVITNAFVISFTSEFIPRMVYQYLYSETGT
MHGFTNHTLAYFNTSNFKPGTAPHDTDFD-RHLRICRYKDYRDPPWSPESYQLSKQYWSVLAARLAFVIFFQNLAMFLSMLVAWLIPDVPRSLKEQLKRE
KTLLMDLLLTEEADK---------------------------------------------
>tr|I3KD17|I3KD17_ORENI Anoctamin OS=Oreochromis niloticus GN=ANO2 (2 of 2) PE=3 SV=1
----------------------------------------PPPESGIELGPGLFFADGKRKVDYVLCYKYKKRRTSKPRLSLS-----------------
-SNGSLPIPI--PMPIPI--QEEKALMREEFEGGLLEAGLQIERDK---SNGMGFIRLHIPWSILSREAELQKIKVAVK-----KKCEL-AGMWDSVATK
INT-FQPDVP-DF--NFKTLKHPFIRDKLH-YDIKSTETLFDNATRSRI-AEIISRTTCRHSC----INSLLARGVYVAAFPLHD------KDQRNDRQL
LHEEWANYGVMHKYQPVDLIRKYFGEQIGLYFAWLGVYTQLLIPPSVLGIIVFLYGILTVDTNVPSQETCNDSLNITMCPLC-GVCDYWRLSSVCSLARA
SYLFDNGATVLFAIFMSLWA-WFLEHWKRRQMYLKHTWDLTSLEDEEIIQRTYVRIEYEEALQEKKAKM--AQQELD-----IEDHLPGYLINISTLLLL
IFITFS-VFG-AVYRICMLSVWSMNPDP-AK--VRMTVTTTGIILNMLVVLVLEEVYGAIAVWLTELELPKTTEEFEERLIFK---LKSMNAFAPIFYVA
FFKG--AGRPGDYVY-----RMEECAPPGCLIELCIQLSMIMLGKQLIQNNVFEILVPKLKKMYRTIQEQKGKNESETEEKRPKQQFDKDFTLEPF-GVS
PEYMEMIIQYGFVTLFVASFPLAPAFALLNNVIEIRLDAAKFVTEIRRPDAVRCKDIGIWYNILCGISKFSVITNAFVISFTSEFVPRMVYQYMYSV-GT
MSGYTEHSLSYFDVSNFPSGTAPNTT----TGVSMCRYKDYRDPPWATDAYTFSKQYWSVLAAKLAFVIFFQNLAMFLSMLVAWMIPDVPRSLREQLKKE
NMLLMEFLLTQDQEKSEEMKVKR-------------------------------------
>tr|W5MRH3|W5MRH3_LEPOC Anoctamin OS=Lepisosteus oculatus GN=ANO7 PE=3 SV=1
----------------------------------------QAEEGEARPQDKNVFSDGVTR-DFVLVWEEEVRENPKATEP-------------------
---------------------DMHQKYRKRFLSRLQKVGIQMDK----EKTRITYVLLNAPWSVLCYYAEEISLRVPLQ---------------------
---KL-----GIA--PPDFYTCQFRNNKLERFLGDNQDTFFKNTQRHQI-YEILARMP---------IDRLVSENIFTAAYPLHDPPGQ--PETLSLRQI
LYQYWARWACWKKYQPLDHIREYYGEKIALYFAWLGFYTGWLLPAAFVGTLVFVFGIWLMMTDVPAREICDGTDNFVMCPLC--ICSFWNLSSICITYKA
GLLFDHGGTVFFSIFMSLWA-TFLEYWKRTTAILSHRWDCSEFEEIE----ERPRPEFTAMAPM-------RNEEPK------SLRFNRTMTGCMVIIIM
ITVVLM-LIA-ILYRTILSIVIYRS--NPFI--AGRIASLTGSVLNLLAILLLSRAYIFLAHILTRWEMHRTQTKYEDAFILK---FQFINFYSSPVYIA
FFKG--VGYPGNYH------RNED-GAGGCLIELAQELLVIMVGKQVI-NNVQEFICPKLRSWWQKRKFHNKEA----KSDVCLPPWEADYQLLVC-GLF
DEYLEMVLQFGFITIFVAACPLAPLFALLNNWVEVRLDAHKFVCEYRRPVVERAQDIGIWFHILQVITHLAVVSNAFLIAFTSDFLPRLYYRYTTE----
LKGYVNFTLSFA-----PESFTQNN--------TMCRYRGFRDQKGH-----YLPEYFNLLAIRMGFVIIFEHFVFFIGRMIDMMVPDIPEEVEIKIKRE
HYMAKEALAENQSLGQKVYLEEP-------------------------------------
>tr|E7FD02|E7FD02_DANRE Uncharacterized protein OS=Danio rerio GN=si:dkey-83h2.5 PE=4 SV=1
----------------------------------------------KPQENKNVFSDGVTT-DFVLVWEESGSP-LKSADG-------------------
---------------------DTHRKWRTEFLSKLQEAGLHQEM----GKTKTTYVLLSAPWNVLCYYAEEISLRVPLQ---------------------
---KL-----HIP--PPDYYTCPFRTTKLERFLGENKDTFFKTTQRHQI-YEILARTP---------IGRLVSEKVLTAAFPLHEPKTQ--PQCLNMRQI
LHHYWARWACWRKYQPLDHIREYFGEKIALYFAWLGFYTGWLLPAAVVGFIIFLFGIWLMVTDVPAEELCSSGNAFIMCPLC--ICSHWNLSSICYTYKA
GLLFDNGGTVFFSIFMSLWA-TFLEYWKRTSSILSHRWDCSEFEEIE----ERPRPEFTALAPM-------RNEEPE------ARRLSRTLTGNMVIILM
ISIVLI-LMA-ILYRTILSIIIYRS--SAFI--AGRIASLTGSMLNLLVILLLSRLYTYLAQCLTRWEMHRTQTEYENAFILK---FQFVNFYSSPVYIA
FFKG--VGYPGSYN------RNED-GASGCLIELAQELLVIMVGKQVI-SNIQEFVLPKLKTWWHKRKLKPARS--EPDTNSQINPWENDYQLLVC-GLF
DEYLEMVLQFGFITIFVAACPLAPLFALINNWVEVRLDAQKFVCEYRRPVVERAQDIGIWLTILQFISYLAVISNAFLIAFTSDFLPRLFYRYT-A----
MSGYINFTLSVA-----PANFTQNE--------MSCRYRGLRDEKGQ-----NTQDYYHLLAIRLSFVIIFEHVVLLIGRIIDWIVPDIPEEVEIKIKRE
HYMAKEALAENQSLSKSVLEEM--------------------------------------
>tr|W5KS51|W5KS51_ASTMX Anoctamin OS=Astyanax mexicanus GN=ANO7 PE=3 SV=1
----------------------------------------------APQKDRNVFSDGVTR-DFVLVWDEPVTP-LKASEP-------------------
---------------------ATHRKWREEFLSKLQTAGLQQEQ----SKTKTTYVLLSAPWNILCYYAEEISLRVPLQ---------------------
---KL-----HIP--PPDYYTCQFHTKKLERFLDENKDTFFKTTQRHQI-YEILSRTP---------IARLITEGAFTAAYPLHEPRGP--PESLSTRQI
LYQYWARWACWKKYQPLHHIREYFGEKVALYFAWLGFYTGWLLPAAVVGFFLSLFGIWLMVTDVPAQEVCHNGENIVMCPLC--ICSYWNLSSICTTFRV
GLLFDNGGTVFFSIFMSLWA-TFLEHWKRTCAVLSHRWDCSEFEESE----ERPRPEFAAMAPT-------RNEEPE------TSRFRRIITGNMVIIIM
VAVVLI-LIA-ILYRSILSIIIYKS--NAFI--AGRIASLTGSVLNLVVILLLSKVYTYLAQILTRWEMHRTQTKYEDAFTLK---FQFVNFYSSPVYIA
FFKG--VGYPGNYY------RNED-GASGCLIELAQELLVIMVGKQVI-NNVQEFVLPKIKAWWNKRKLHPTQR--GANITENVAPWETDYELLMC-GLF
SEYLEMVLQFGFITIFVAACPLAPFFALVNNWVEIRLDSQKFVCEYRRPVAERAQDIGIWFTILQVITYLAVISNAFLIAFTSDFLPRLYYRYTTE----
LRGYMDFTLSVA-----PNNFSQSH--------MQCRYRGFRDDKGH-----HTPEYYNLLAIRLGFVIIFEHVVFLIGRMIDWMVPDIPEEVEIKIKRE
QYMAKKALAENQSLEEVLLNET--------------------------------------
>tr|I3JH93|I3JH93_ORENI Anoctamin OS=Oreochromis niloticus GN=ano7 PE=3 SV=1
----------------------------------------TTRSKQPVPQLGNYFRDGRTKIDFVLVWEIRSRRKRREKGTNM-----------------
-A-------------------AQLAQWREKFVQNLESVGLVMEK----EKKTIHFLKISAPWDVLVCYAEELCLRAPLQ---------------------
---KL-----CIP--PLDYYTCAFRKSKMSRFLGEDQDTYFTNTQRHRV-YEILARTA---------VDRLLNEGAYTAAFPLHEPKHE--PDELNQRQV
LYYYWARWCKWYKYQPLDHIREYFGEKIALYFAWLGFYTAWLLPAAVVGTLVFVSGVMSMGTNTPAEEICNSGASYTMCPLC--TCKAWNMSEICTLTKL
GYLFDHPGTVFFSVFMSFWA-TFLEYWKRKMATLAHHWDCMDFHEEE----ERPRPEFAAMAPT-------QNKEPE------KTRLSRMFTGSMVIIMM
LCVVMI-LVT-VVCRGIISVVIFHS--SPLR--AGTIANISSSIVNLGLILLMGQVYTALAEQLTKWEMHRTQTQYDNAFIFK---FQFVNFYSSPFYVA
FFKG--VGYPTNYG------RNED-GAGGCLIELAQQLFIIMVGKQLI-NNVQEFILPKVKAWRQKRTLAKVLG----A-SHEPRRWEEDYKLVEC-GLF
EEYLEMVLQFGFITIFVAAFPLAPLFALLNNWVEIRLDAHKFVCEYRRPVAERAQNIGVWFNILEALSHLSVIANAFLIAFTSDFLPRLLYQYKFD----
LNGYVNFTLAYA-----PLNYTEYPMCR---------YKAFRDNNGN-----YTLFYWELLAVRLGFIIAFEHVVFFVLRAIDWIVPDVPESLELKMKRE
RYLAKQALAENQEALLVSRARAA-------------------------------------
>tr|M4ADD8|M4ADD8_XIPMA Anoctamin OS=Xiphophorus maculatus PE=3 SV=1
--------------------------------------------------MGNHFRDGRTKIDFVLVWEIRSRGKQRGKGKSN-----------------
-G-------------------AQQAEWRDKFVQNLQSAGLLLEK----EKKTIHFLKVSAPWDVLVYYAEELCLRAPLQ---------------------
---RL-----CVP--PLDYYTCAFRKSKMNRFLGEDQDSYFTNTQRHQV-YEILARTV---------VDRLVNEGAYTAAYPLHEPSHE--ADELNQRQV
LHYYWARWCKWFKYQPLDHIREYFGEKIALYFAWLGFYTAWLLPAAIVGTLVFVSGVMSMDTNTPAEDICTSGAKYPMCPLC--TCDAWNMSDICTMAKL
GYLFDHPGTVLFSVFMSFWA-TFLEFWKRKMATLAHHWDCMDFHEEE----ERPRPEFAATAPT-------ENKEPE------KTRLSRMFTGSMVIVLM
LCVVII-LVT-VMCRGVISVMMYQS--SPLR--AGTIANICSSIVNLGFILVMGQVYTALAEQLTKWEMHRTQTQHDNAFTLK---FQFVNFYSSPFYVA
FFKG--VGYPTNYG------RNED-GPGGCLIELAEQLFIIMVGKQLI-NNIQEFIIPKVKAWRQKRTLASVLG----E-QDEPRLWEEDYKLVPC-GLF
EEYLEMVLQFGFITIFVAAFPLAPLFALLNNWVEIRLDAHKFVCEYRRPVAERAQNIGVWFNILEALSHLSVIANAFLIAFTSDFLPRLLYQYKFR----
LNGYVNFTLAYA-----PLNYTDYPRCR---------YKAFRDNDGM-----YTLFYWELLAVRLGFIIAFEHVVFFVLRAIDWIVPDVPESLELKIKRE
RYLAKQALAENQEALLSSSNKKS-------------------------------------
>tr|F6YFE4|F6YFE4_CIOIN Anoctamin OS=Ciona intestinalis GN=LOC100182959 PE=3 SV=2
---------------------------------------------EKDQIKECYFRDGIRKIDFVLVYEDEHCEKTEELSS-------------------
---------------------EQQEKWRNKFIRCLKQTGVTIEE----EEKTIHYFKLNCPWHLLTYYAEELNIRAPLQI--------------------
---KF-----HLP--PKLYFTCTFRKSKISNFLGDNHDTYFSATERGRI-WEILQTTL---------IERLLCDGVFTAAFPLHDPKPIDLLEKLNKRQI
LYEYWARWGRWYKYQPLDHIRDYFGEKIGIYFAWLGFYTAWLLPVAFIGFIVFLAGLIGINMNPEAKDVCGSGNSYMMCPPC--GCKKWPLSKSCIMMKL
AYLFDNNGTVTFAIIMSFWA-FFLEFWKRKSANIAHHWEVMDYEEEE----ERPRPEYNARAPT-------VNVESP------KQRLRRMFTGFAILIIM
LVVVVI-VLS-ILYKCLIGVVMSHS--DKIH--VSTIRSVSGALLNLILIMLMSNVYTAVAEWLTRWEMHRTQTEYENALTFK---FQFVNYYSSIFYIA
FFKG--VGYPGHYG------RNEA-GSGGCLIDLALQLFIIMVGKQAI-NNVQELILPKLFQWWQRRQVKKAFG----QKSKMTKPWEKEYKLVHY-GLF
EEYLEMVLQFGFITIFVAAFPLAPLFALLNNWIEIRLDASKLVCEMRRPVAERAQNIGVWYEILDALVQIAVITNAFLIAFTSEFIPRILYKYEVGA---
LKGYTNHSLSYA-----PTSAVSYTQKT--KSLGDCRYKGYRDWEGH-----HTLYYWKLLACKLAFVITFEHLVFFIGRMIDWSVPDVPESLQYKIKRE
HYLAKQALADNRDNSMNNKGESS-------------------------------------
>tr|H3B189|H3B189_LATCH Anoctamin OS=Latimeria chalumnae GN=LOC102360131 PE=3 SV=1
----------------------------------------NSSSCSP-DLKGNYFRDGTTKIDFVLVWEEKLQPHKKKKVRYT-----------------
-Y-------------------SKHQRWKEKFIRNLHNAGLLMEK----DRKTIHYLKLSVPWDVLAYYAEELCMRAPLQ---------------------
---KL-----RIP--PMDYYTCAFRKSKLEKFLGENHDAYFTNTQRHRI-YEILARTA---------IDRLLNEGVYSAAFPLHEPEYE--PEELNPRQI
LYNYWARWSKWYKYQPLDHIREYFGEKIAIYFGWLGFYTTWLLPAAIVGTFVFISGLISMGTNTPAEEICNSGGRYPMCPLC--NCGTWNISEICSMAKL
GYLFDHPGTVFFSIFMSFWA-TFLEYWKRKNATLAHHWDCMDFEEEE----ERPRPEFAAMAPL-------QNKEPE------KDRLSRIITGSMVIIIM
LCVVMI-LVT-IMYRGIISMIMYRT--NTLM--AGNIANISSSMVNLILILLMSQVYTSLAEQLTKWEMHRTQTHYEDAFTFK---FQFVNFYSSPFYVA
FFKG--VGYPGHYG------RNED-GPGGCLIELAQQLVIIMVGKQII-SNIQEFIVPKVKAWLQRRKLAAIRG----I-SQEPKRWEEDYELIEC-GLF
EEYLEMVLQFGFITIFVAAFPLAPLFALLNNWVEIRLDAQKFVCEYRRPVAERAQDIGVWFNILEALAQLSVIVNAFLIAFTSDFLPRLLYQYEYD----
LRGYVNFTLSYS-----PHNYVINN-------HTMCRYKSFRDENGN-----QTLFYWKLLAVRLGFIIAFEHVVFFILRCIDWMVPDVPESLEVKVKRE
RYLAKQALADNQDVLLTVSQDSI-------------------------------------
>tr|T2MD20|T2MD20_HYDVU Anoctamin OS=Hydra vulgaris GN=ANO4 PE=2 SV=1
----------------------------------------G---RKEMTSNDLYFEDGIRTIDYILAYEVAEDKNNLSEQK-------------------
-----------------------KKDERNMFLDNLKAEGLEIEETSSLEEDVIRFIKVHAPFNVLCEYAENLKMKMPIKYDWYYY---------------
---PFVIRDKYTR--EKKYFVKVFDRDQISEFIYDKP-NFFSTIKRRRI-YSILEKVKYGKG-----IDNLQARGIFLDIFPLHR-------IPINDRQY
LQEDWASIRRVFKYQPIEAIRNYFGEKVALYFAWLGFYTSFLVPASIVGLLCFLYGIFSTF-SPIVKEVCNPHYKFYMCPLC-KLCSYYLLHQGCFYSKI
THYFDNNSTLFFSVFMSLWA-IYLEFWKRKEKSLAYEWHTMDFEEDE----EQPRPEYLAKVT---Q----KNKEPI------SQRYSRIFGAFGVALFF
VILVIS-VFG-IVFRAAFYIFLIRQNNRAIR--SKMVVSASAACVNLLAINMLKFVYERIAVKLTNWENPRTFTEYEDSFTIK---FQFVNTYASIFYVA
FFKS--FVGSPGNYN-----RFDGCSVQGCFLELTIQLVIIMVGQQII-GNVMEIGIPFLKNKYRNWRYAKL-----SYTEANQPQWVADFEGEIQFSLF
WQYLEIVLQYGFVTMFVAAFPLAPLVALLNNIVEIRLDAVNFIHNFRCTHANPAQDIGAWYGILATLTMLSTIVNGFVLAFTSELIPHLVWIYYKSPDGK
LDGYVNWSMSKFRVSDFKNNSRP-------LKQEFCRYPGFHNET----PYGYSEDYWIVLTARLAFIIAFQAFVISVKETIAYIIPDIPKSLELKIKRE
KYLAEKQERRHKEKIGKRRPSKI-------------------------------------
>tr|W5KZI6|W5KZI6_ASTMX Anoctamin OS=Astyanax mexicanus PE=3 SV=1
----------------------------------------EKPATPPAPPPGNYFRDGQTKIDYVLVWEIKSRRKRRARGKGR-----------------
-G-------------------AQLARWRDRFIQNIQSAGLLLEK----AKKTIHYLKLSAPWDVLVYYAEELCLRAPLQ---------------------
---KL-----WVP--PVDYYTCAFRKSKMEKFLGEDHQNYFSITQRHRI-YEILARTV---------AARLLNEGAFKAAFPLHEPDYE--PDQLNKRQI
LYHYWARWSKWYKYQPLDHIREYFGEKIALYFAWLGFYTAWLLPAAIVGTFVFVSGIMTMGSNTPAKEICESGGHYLMCPLC--TCKPWNMSDICPMAQV
GYLFDHPGTVFFSVFMSFWA-TFLEYWKRKNATLAHHWDCMDFHEEE----EPPRPEFAAMAPA-------ENKEPE------KARISRMLTGSMVIVIM
LCVVMI-LVT-IIYRSIVSVMMYET--SSLR--AGNIANISSSMVNLALILLMGQVYTALAEQLTKWEMHRTQTQYEDAFTFK---FQFVNFYSSPFYVA
FFKG--VGYPGHYG------RNED-GPGGCLIELAEQLFIIMIGKQLI-NNVQEFVIPKVKAWRQKKALASVKK----G-GLEPQRWEQDYELVAC-GLF
DEYLEIVLQFGFITIFVAAFPLAPLFALLNNWAEVRLDAHKFVCEYRRPVAERAQNIGVWFIILEALSHVSVIVNAFLIAFTSDFLPRLLYRYKFN----
LHGYVNFTLAYA-----PPSYNYSS-------HGMCRYKAFRDENGS-----YTLVYWELLAVRLGFIIAFEHVVFSVLRVIDWMVPDVPESLELKVKRE
RYLAKQALADNQEALLQATRLAT-------------------------------------
>tr|T1ISC6|T1ISC6_STRMM Anoctamin OS=Strigamia maritima PE=3 SV=1
----------------------------------------TMNNNAIPEDKDTYFRDGKRKIDFILVYEESNSSTSDSSSPKL-----------------
-T-------------------QKLEYWRQKFMSNLRKAGLDMEEEVIE-SITTHFIKLSAPWSVLVHYAEELNMRAPLQ---------------------
---TL-----HIP--PLNFYTCAFKKSKIDRFLGDNHDSYFISTQRHQV-CEILQTAT---------IDRLISRGVYTAAYPLHEPEA---PEQLNMRQI
LFEYWARWGRWYKYQPLDHIREYFGEKTAIYFAWLGFYTGWLLPAAIVGLLVFMYGVVTMDLYVPAKEICESGDAFKMCPQC-IGCTYWSLSDICVLSTV
SYLFDHPGTVFYAIFVSFWA-SFLEYWKRKSASLAHHWDCLDYADEE----ERPRPEFAAKAPL-------RNREPK------ALRGKRMVAGLGVLLVM
ISLVII-IVA-IVYRVLISIP---L-QNQLR--ATTIASMTGAVVNLIFIIALSRVYTRLAHLLTEWEMHRTQTEFEDNLIFK---FQFVNFYSSIIYIA
FFKG--VGYPGHYN------RQED-GNSGCLVELAQQLIVIMIGKQII-NNAQEILIPKIKAWRHRKKVTT--------KNKEKTRWEEDYQLIEN-GLF
DEYLEMILQFGFITIFVAAFPLAPLFALLNNWVEIRLDAHKFVCEMRRAVAERARNIGVWFTILEALAQLAVISNAFLIAFTSDFLPQLLYTAHF-----
LQGYINYTLSYA-----PNGTMT----------EECRYRDFRDEHGQ-----HTLFYWELLAIRLVFVIVFEHVVFGICRLIDILVPDIPSSLELKIKRE
RYLAKQALADSDTIMKAASRKDD-------------------------------------
>tr|K1QDE4|K1QDE4_CRAGI Anoctamin OS=Crassostrea gigas GN=CGI_10022869 PE=3 SV=1
----------------------------------------LDGDRGDQYNFSCFFSDGKRQTDFVLVYEEELDNAKKKS---------------------
---------------------SIYDKWRAKFMVNLRKNGLELEEERIQ-KKITFFIKIHAPWDVLCFYAEDLCFRAPLQ---------------------
---FL-----HIP--PMDFYTCQFKTSKLERFLGDNKDTYFTNTQRHRV-WEILSTTG---------IERLLEEDVFKAAFPLHDPVHGI--EDMNLRQI
LYEYWARWGKWYKYQPLDHIREYFGEKIGIYFAWLGFYTAWLLPAAVVGIIVFVYGIVSMVNNVAVNDVCSSDKDYKMCPLC-IGCAYWYLSDVCTYVKI
AYLFDHPATVAYAVFVSFWA-TFLEYWKRKNASLAHHWDVLDFEDEE----ERPRPEYAAKAPT-------KNKEPP------RDRIPRILSGFAVIIIM
MSLVLI-IVA-IMYRILVSIP---L-QNKLR--ANLIASTSSAVVNLILIMALGKVYEKLALKLTQWEMHRTQTEFEDQLTFK---FQFVNFYSSIIYVA
FFKG--NGYPGHYT------RNEE-NNGGCLIELTQQLAVIMIGKQMI-NNAQEILIPKVKAFMHRCKVSL--------KNAVRSRWEEDYQLIEN-GLF
EEYLEMVLQFGFITIFVAAFPLAPLFALLNNWVEIRLDAHKFVCETRRPVAERAQDIGVWFKILDALAQLAVISNAFLIAFTSEFLPRLLYQYQY-----
LQGYINFTLAVS-----PSGTLN----------QTCRYKEFRDEKGE-----YTLFYWHLLAVRLAFVILFEHVVFGICKLIDFLVPDVPEALELKIKRE
RYLAKQALADTDAIMKIARGDDE-------------------------------------
>tr|T1JS39|T1JS39_TETUR Anoctamin OS=Tetranychus urticae PE=3 SV=1
-------------------------------------------PYRFFDEQTSYFKDGKSKIDYILVYEERTRSNVSFETQDE-----------------
-T-------------------RKERKYRERFINNLRKIGLLIEEEVLPSSPTIYFFKISIPWPVLAQYAEKLNVRAPLQYP-------------------
---IL-----KIS--PLQYFTCPFKISKIDRFLNDEPDTIFTTNQRIRL-HEILQSTV---------IARMLNEEIFTGAFPLHEKEY---PNEMNKRQV
LYQYWARWSCWYKYQPLDHVQQYFGEKIAIYFAWLGFYTSWLLPAAVVGLLVFIYGVATIGQDVVSKEICESGTKYRMCQNC-PGCPYEYISQTCFFARL
SYLFDQPGTVFYSIFVSFWA-AFLEYWKRKSASLSYHWDVMSFEEE-----EKSRPEFVARAPF-------RNQEPN------RIRYQRMAAGLMLIALM
LSLVVV-VVA-IIYRLLVSIP---L-MNPLS--ASIIASSTGALANLIFIMLLSPVYEKLAFRLTQWEMHRTQTEFDNHLTFK---FQFFNYYSSIFYIA
FFKG--IGTPGNYA------RNEN-SNNGCLGELAQQLGVIMIGKQII-NNAQEILWPKMKTWWHQRRTNIPS------GKEGMTRWELDYSLLPY-GLF
EEYLEMVLQFGFITIFVAAFPLAPFFALLNNWVEIRLDAQKLVCQTRRPIPERAQNIGIWFSILTFLAQIAVISNAFLIAFTSDFLPKLVYSFEN-----
LHGYLDFSLSWA-----PANTTS----------LPCRYRDFRDPNGN-----LTLTYWKLMFVRIAFVCIFEHVVFSVSKLIDVIVPDVPRRLEVQIKRE
RYLAKQALADSDTILQAATEKIA-------------------------------------
>tr|A0A0N8D395|A0A0N8D395_9CRUS Anoctamin-5 OS=Daphnia magna PE=4 SV=1
----------------------------------------NGKQVKHPKSIGTYFRDGRRKIDYVLVHEEVSLAPSRSRNHN------------------
----TTIQS---SLPLPF--RNRKIDTRKTFIDKLKSQGIEIEEEFAEKRTNVRFIKLHAPFPLLAHWAEELGFRARILQA----------RLF----KS
---CFAQEIPG----PKVCCTYPFRRS-IATLLGLDSESYFTSTERSRI-NEILARTTYGDRR----IERLLKEGVYTASYPLHE------QEKLNPRQI
LHGYWARWSKWSKYQPLDNVREYFGEKIAFYFAWLGFYTGWLIPPSIVGVLIFVYGLLTVD-DPASSQVCRSIGQYPMCPLC-QGCHQWDLSDVCTYSKL
SYLFDHPGTVAFAIFVSFWA-TFLEYWKRYSARLAHRWDVVDVEREE----IRPRPEFALKAPS-------TNAEPHSVR-------KRIMAGVCFVFLM
VCMVII-IVA-IVYRIVVSIPLFQHT---LKSQAQVIANLSGAVVNLVLIMALGRFYEKLAYKLTTWEMHRTQIEFEDNLTFK---FQFVNLYASPFYIA
FFKG--VGYPGNYLH-----RNEECSAGGCLVELSQQLFIIMVGKQVI-NNAQEILWPKVQAWWQNRKVEFTQ------DKGKSKRWEADYQLVEN-GLF
QEYLEMVMQFGFITIFVAAFPLAPLFALLNNIVEIRLDAQKFVCNTRRTVGHQAKNIGIWLRILEFLVHLAVISNAFLISFTSEFLPKILYQYEHSW--S
MDGYVNFTLAISPKG---------------SMIEPCYYRSFRDEDGN-----LTAFYWKLLVVRLAFVVIFEHFVFGVCRLIDAVVPDVPKTLAIKMKRD
RYLAKQILQDPEHHIRISECT---------------------------------------
>tr|R0L3E7|R0L3E7_ANAPL Anoctamin OS=Anas platyrhynchos GN=Anapl_09044 PE=3 SV=1
----------------------------------------AGEASLGEKSTANVFSDGCTR-DFVLVWETVPRELSGQKGSRE-----------------
-N-------------------TIHRTWRKKFLDKLHAAGLHMEKSNLGEKKVVHYLLLSAPWSVLCYYAEELQLRVPLQ---------------------
---RL-----GIP--PLDYYTCPFKVNKLQWFLGDEQDTFFSTTQRHQI-YEILATTQ---------------------------PPEE--SGSPSPRQV
LFQYWANWRKWSKYQPLDHVRKYFGEKVAFYFAWLGFYTGWLLPAAVTGTVVFIAGIFLVFSDVPAQEICESKEQFRMCPLC--SCPYWQLSDTCSTFMA
GRLFDHGGTIFFSIFMSLWA-LFLEFWKRTNASLAHRWDCSEFEDIE----ERPRPQFTAMAPM-------INEEPK------RSRIHRILAGLVVLIML
IAMVVL-VIS-ILYRTVVAILLSSS--YFFV--ASHIASISSSVVNLFFILILSKIYISLAHLLTKWEMHRTQTKYEDAFTFK---FQFVTFYSFPMYIA
FFKGXXLSYPGNYW------RNEECSPGGCFIELAQELLVIMVGKQII-NNVQEVAIPKLRCWWHKHKLLSTKK--GGPVPAEQAPWVVNHQLLAF-GLF
DEYLEMVLQFGFITIFVAACPLAPLFALLNNWVEIRLDARKFVCDYRRPVAERAQGIGIWFSILEVITHLAVSSNAFLIAFTSDFLPRVYYEYIHD----
LRGYVNFTLAYA-----PWDFVQQS-------NTVCRYRAFRDQDGN-----LTLTYWHLLAVRLGFVIVFEHVVFFIGRVIACLVPDIPESVEVKVKRE
RYLAKEALAENKRSSRSHSPKRS-------------------------------------
>tr|A0A068X6H1|A0A068X6H1_HYMMI Anoctamin OS=Hymenolepis microstoma GN=HmN_000607100 PE=3 SV=1
----------------------------------------LDGNEYYSTSPEMFFQDGKRRIDYVLVFKSGEVDE-------------------------
----------------------TVKSKRYAFLSALAEQMIEIEVENCQARQDLVFVKLHASWSTLIRVAEVLQFRKPLKVK-------------------
---CFDLDSKNIF--LPAPYRAPFSRSRMGLFEI-DYDKFFTPSERSLV-DFVLKRTGTRTRVMGPLIDNLINEKVFLAAFPLHE----TSMVENNMRTL
LTSQWANLKMMLKYQPLDYIRLYFGESIAFYFAWLGLYTYWLIPVGIFGLLVFCLSAIDI-DDRVVEDVCNGGGEIVMCPTC-KGCKLWLLNSSCFATKM
THLVDNIGTVLFAVFMAIWA-LFMENWKRYQNVLAYRWNVQNLESID----EPPRPEFLALIKKRGY----VNEEPF-----WSKKLPITTLSFVSVLFG
ILLCLA-LIG-IFYRLVVNTLLLQSQNVFIN--AGMITTVTSSCINLVCIFILKFVYDKIAVKLTDMENHRTQSEYDDSLTLK---LQFVNFYSSIFYIA
FIQG--ASLPGDDS------RSSGCDNGNCLFQLFIQLAIIMVGKQFL-NFLTENTIPPIKRCLSVYFAQRRSNTLKGPDRPILYNCRINYTLLDGRPLF
EEYLEMLIQYGFITMFVPAFPIAPLFALLNNMVEIRTDAKKFLRLMRRPTIKREKGIGIWFGILSVVSSLAIRTNACLIAFTSDFLARMTYALYYSP--N
LVGYVEFSLSYMNVSRFTLTAK--------GN-TYCRYRDFREPPTS-YPYTYTPVYWHILAVKFAFVFIFENVAIALCAFLAKCIPDMPKSLVIISRHE
ARVIGELELDDDKEDAWEPPTSQ-------------------------------------
>tr|U6JHY6|U6JHY6_ECHGR Anoctamin OS=Echinococcus granulosus GN=EGR_10154 PE=3 SV=1
----------------------------------------EYYS----ESPEMFFRDRKRRIDFVLVYKAEETD--------------------------
---------------------TVSKSKRFAFLSALAEQMIEIEVENCQANDDLVFVKLHASWSTMIRVAEVLQFRKPLKAK---T---------------
---CFELDP------LPSPYRAPFSRT-MNLFDIEDYDNFFNPTERSLV-DYVLKRTGTCECTGPGTIDHLINDKVFIAAFPLHD----SSQTEVNMRTL
LNDQWGSLKNMIKFQPLDYVRLYFGESIAFYFAWLGLYTYWLIPVGIFGLLVFCLS-AIDIDDRIVDDVCNRGSEFVMCPTCSRGCKFWLLNASCLATKM
THLVDNISTVLFAIFMSIWA-LFMENWKRYQNVLGHRWNVQHLEPVD----EPPRPEFLALLKKRGYK---VNEEPF-----WSRKLP-TVLSFSSVILG
-VLCLA-LIG-IFYRLIVNTLLLQHE---ISSMAGIITTVTSSCINLVCIFILKLVYDKIAVKLTDMENHRTQSEYDDSLTLK---LQFVNFYSSIFYIA
FIQG--AGLPGDRSI---------CDNGNCLFQLFIQLAIIMVGKQFL-NFVTENTLPPIKRCLVVYFAHRRSMPTSGDGRPILYNCRANFTLLDGRPLF
EEYLEMLIQYGFITMFVPAFPVAPLFALLNNMFELRTDAKKFLRLLRRPVRKRENGIGIWFGILTAISALAIRTNACLIAFTSEYLVRMTYILYYSPNRT
LEGYLDFTLSYMNASRFDLTPKDE------KNSTYCRYRDFREPPTAPDPYAYTPVYWHVLAVKFAFVFIFENVALALTALIARCIPDMPQNLTIISRHE
ARVVNELLLQNEEIEDKEKSFEP-------------------------------------
>tr|L9L1V9|L9L1V9_TUPCH Anoctamin OS=Tupaia chinensis GN=TREES_T100000384 PE=3 SV=1
----------------------------------------TKFQKHKHSKDSIFFRDGIRQIDFVLSYVDDVKKDGDLKA--------------------
-------------------------ERRKEFEQNLRKTGLELEIEDKREDGKTYFVKIHAPWEVLVTYAEVLGMKMPIRSD-------------------
---PVKLPENVK---RPEYFTAQFSRH----FLIEDQSRFFPSSSRNRI-YYILSRCPFGIE-----IERLLNSNAYSSAYPLHD----PSPNPPNARYI
LHQHWARFSYFYKEQPLDLIKDYYGEKIGIYFVFLGFYTEMLFVAAVVGLACFIYGLLSME---SSIETCDPKGQMIMCPLCDLVCDFWRLNSTCLAAKF
SHLFDNESTVFFAIFMGIWV-LFLEFWKQREARLEYEWDMVDFEEEQ-------RPEFEAMC---------RNMEPLY-------RVPWY-LSGATVTFW
MTLVVA-MVS-IVYRLSVFATFASFETEALK--PQITTALTGSCLNFIIILILNFFYEKISAWITKM--PRTYQEYESSLTLK---FQFVNYYSSCFYVA
FFKG--VGYPGKYTYLFNVW-SEEVRILLR---AV---------FHVF-TF--ITPNSMALNWWRRRR-------RTNSEKL-YSRWEQDHDLETFLGLF
YEYLETVIQFGFVTLFVASFPLAPLLALLNNIVEIRVDAWKLTTQYRRPVAAKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYYYAYST-QP
LRGYLNNSLSVFLIADFPNYTVPPEKRDF-T----CRYRDYRYPPDHEKKYFHNMQFWHVLAAKMTFIIIMEHVVFLFKFLLAWMIPDVPKDVVERIKRE
KLMTVKILHDFELNKLKENLGLD-------------------------------------
>tr|A0A0Q3ZU63|A0A0Q3ZU63_ALLMI Uncharacterized protein OS=Alligator mississippiensis GN=Y1Q_005732 PE=4 SV=1
----------------------------------------VSNSSQGEQDTANVFSNGHTR-DFVLVWETACRPQEGQGDEGS-----------------
-D-------------------VLHKFWRKKFLNKLQAIGIRMEK----KKKAVHYLLLSAPWSVLCYYAEDLSLRLPLQ--------------WS-----
---RL-----GMP--PLDHYTCQFKVNKLQWFLGKEQDSFFNSTQRHQI-REILATTP---------VDRLLNEGVFTAAFPLHDPPEG--ANTLNQRQI
LFQYWACWRNWNKYQPLDHIRQYFGEKIAFYFAWLGFYTAWLLPAAVVGTLVFIMGVFMMFDDVPSQEICESEDQFQMCPLC--KCPYWLLSSICSMFMA
GRLFDHGGTVFFSIFMTLWA-MFLEYWKRMNATLAHRWDCSDFEDIE----ERPRPEFVAMAPM-------RNEEPK------RNQIHRILAGSMVIIMM
ISVVVM-LIS-ILYRAIVSLLVASS--DFFV--ASRIASLTGSVVNLIFILMLSKIYIALAHFLTKWEMHRTQSKFEDAFTFK---FQFVNFYSSPIYIA
FFKG--VGYPGHYG------RNEE-GPGGCLIELAQELLVIMVGKQMI-NNVQEIVLPKLKGWWQKYNLRSKTT---SSAPVPPAPWQSNCELLVP-GLF
DEYLEMVLQFGFVTIFVAAFPLAPLFALLNNWAEIRVDAQKFVCEYQRPVAERAQGIGIWFYILEVITNLAVISNAFLIAFTSDFLPRLYYQYTYA----
LRGYVNFTLAYA-----PATFVSQY-------NITCRYRAFREVTGQ-----YSLIHWNLLAIRLGFIIVFEHVVFFITRLIELMVPDLPESVEIKVKRE
RYLAKQALAENQVLLEAKGGLSK-------------------------------------
>tr|A0A087YEY8|A0A087YEY8_POEFO Uncharacterized protein OS=Poecilia formosa PE=4 SV=2
----------------------------------------ANLVEYNNQPDSLFFNDGVRSVDFILVYEDEDTKPF--DK--------------------
---------------------KRHKKRREYFEGCLMKMGLELEATPS-HGDNLMYVKVHVPWEVQRTYAEVLHIKIPIEND-------------------
---HFKPNEKLI---EVDHYTAPYQKH----FLKMDKERFFTPSMRSRM-NFIMCRAPYEIR-----ITKLLNTGVYKAAYPPHD----KSESCPNERYL
LYKEWAHPKNFYKTQPLDLIRKYYGEKIGIYFAWLGFYTKMLAFASVVGLACFFYGYHIQE---S-KEVCDPDGKIVMCPQCD-LCNYWILNSTCDTSKT
LTIFDHFGTLVFAVFMAVWV-VFLEFWKRYQSQLEFEWDTVEFL--E-------RPEYDAAC---------INVQPFT---FC--RCFRI-IGIGTVLFW
IVLILA-IVA-IIYRLAVFFSLSIKKNP-LE--PQMATSVTAGLINFVVIMILNTLYERVAIWITDF--PRTRTDYENSLTLK---FQFVNYYSSCFYIA
FVKG--VGHPGQPVYILGKY-NEECDPGGCLIELTTQLAIIMGGKAIW-NNIQEVLLPWVKNLIFRY-------CRVTPKKVEPPRWEQDFELQPFLGLF
YEYLEMVIQFGFVTLFVASFPLAPFLALVNNIIEIRVDAWKMTTQFRRILPEKARDIGAWQPILQWIAILAVATNAMIIAFTSDIIPRLVYYEE--G-HS
MSGFINSSLSYFNTDDFSKATVTDA------------YRDFRFPPGHPRQYQYNMHYWHVIAAKMAFIIVVEHVAYLTKFILASVIPDISHTTREHLKRE
RYLTQAIIHEVRLNLVSKRLKPV-------------------------------------
>tr|A0A099Z517|A0A099Z517_TINGU Anoctamin OS=Tinamus guttatus GN=N309_14548 PE=3 SV=1
----------------------------------------LKSETNAMASSGLFFKDGKKRIDYILVYKKSSPQ--------------------------
------------------------VEKRSTFEKNLRAEGLMLERE---TNSDIMFVKIHCPWETLCKYAERMNIRMPFRKK--------TMGS-----LQ
--RPMKLDKEALP--ETDCYTAPFSRA----FTINNKDSFFSNSTRSRI-HHMLQRTKYEDG-----INRLLNNGTYEAAFPPHE----RHHGAQNHRHL
LYERWARWGMWYKYQPLDLI-RYFGEKIGLYFAWLGWYTGMLIPAALVGLFVFLYGLFTMD---SSKEICEA-NETIMCPMCERNCTLQKLNESCMYAKV
THLFDNGGTVFFAIFMAIWA-VFLEFWKRRRAVLTYDWDLIDWEDEE-------NSYIRIVFAIWVIF---VSPEPFP-------KLSRL-VSVSGIFFM
ISLVLT-VFA-VVYRLVAMEQFASFWYFI-K--QF-ATSGTGVCINFMIIMSL-VVYEKVAYLLTDL--PRTESEWENSFALK---FQFVNLNSSIFYIA
FFLG--AGRPGKYNKLFN--RLEECHPSGCLIDLCLQMGVIMVLKQMW-NNFMEG-YPLLQNWWSRRKMKKGG--QLMEHKISLPQWEKDWNLQPMHGLM
D--LEM-LQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPMPARATDIGIWYGILEGIGVLAVITNAFVIAITSDYIPRFVYAYKYGP-KC
LKGYVNSSLSVFDLSELGM-G---Y-------SGYCRYRDYRAPPWSSTPYEFTLQFWHVLAARLAFIIVFEHLVFGIKSFIAYLIPDMPKDLCDRMRRE
KYLVQEMMYEAELEHLQKERK---------------------------------------
>tr|A0A0Q4AK45|A0A0Q4AK45_ALLMI Uncharacterized protein OS=Alligator mississippiensis GN=Y1Q_000145 PE=4 SV=1
----------------------------------------G--EHDKNKSNGLYFRDGKCRIDYILVYRKSNLQ--------------------------
------------------------TEKREVFERNIRAEGLQMEKES--TNSDIIFVKLHAPWEVLGKYAEVMNVRMPFRRK--------FM-------NR
IEKPMKLDKETLP--ENDCYTAPFSQQ----FIIHNKDTFFNNATRSRI-HHILQRVKYEEG-----LNRLLSNGSYEAAFPLHE----KNHGAENHRHL
LYECWASWGVWYKYQPLDLV-RYFGEKIGLYFAWLGWYTGMLFPAAFIGLFVFLYGVTTLS---CSKEVCQA-TDIIMCPICDKYCPFMRLSDSCVYAKV
THLFDNGATVFFAVFMAVWA-VFLEFWKRRRAVIAYDWDLIDWEEEEVQQVV--RPQFEA------KY---MNPEAFA-------KCSRL-VSASGIFFM
ICVVIA-VFG-VIYRVVTVSTFAAFWALI-N---QVATTGTAVCINFSIIMLLNVLYEKVALLLTNL--PRTESEWENSFTLK---FQFVNLNSSTFYIA
FFLG--TGHPGAYLRLIN--RLEECHPSGCLIDLCMQMGIIMVLKQTW-NNFMEG-YPLIQNWWTRRKLRQEH----SHRKASFPQWEKDYNLQPMYGLF
D--LEM-LQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLASRAKDIGIWYGILEGIGILSVITNAFVIAVTSDFIPRLVYAYKYGP-KC
MVGYVNASLSVFLVSDFENRSEPASNGSEFSPLKYCRYRDYRDPPHAPVPYGYTLQFWHVLAARLAFIIVFEHLVFCIKHLISYLIPDLPKDLRDRMRRE
KYLIQEMMYEAELERLQKERKER-------------------------------------
>tr|I1GDN9|I1GDN9_AMPQE Anoctamin OS=Amphimedon queenslandica PE=3 SV=1
----------------------------------------RKQERDTEDQDTVYFKDGVRKIDICLTYKDLIDAKKGKGDEE------------------
---------------------AKRADKRKAYFEALERKGLQFEYQDPK-DGETWFVKVHATFPALEKGAEDLLIRMPIQVDWYRSTL-------------
---FFDPKVPKPF--HADFFTAPYVAKKRANFHGDDEANFFSSAQRSFI-WNILENTQYGPNEDQVGVSRLVQNSTFTSAFFLHD------E-IDNERQL
LHYEWSHPKNFYKYQPLENIRHYFGEKIGLYFAWVGFYTSWLGFASIVGIIVMIAGLFTLSYNELARDICNDTAEFYMCPLC-ETCDFWYYRSACGFARV
SLLFDYGGTVFFAAFMACYA-LFLEFWKRTEKQLQYQWDTLGFEEAE----QRERPEFVQAIKKKIKNYP-KNYEPA------FDIAPKLVLGFVILITM
VIAVLG-VFA-LIYRLAVSTSIYRLVQNLGP--ADLTVSITGSLIQLVFIVIMNQVYERLATWLTSWELHRTTTEYEDSFTFK---FQFINFYTSIFYIA
FIKG--TGYPGGYD------RLDECSAYGCLLELTIQLAIIFLGKQVL-NDISELGVPYAKTILKKVMRYRKEK---TEEDDSFVRWEKDFELIPLHGLF
FEYLELVIQYGFVTIFVAAFPLAPFFAWVNNVIEIRLDAHKFIQVFRRPLAERAQDIGLWFHLLRFVTNLSVVTNALLIAFTSQFIDRELFDRVYKNNSG
RGGFVRWATSSFSLTALLQSATPNGDTNFPNTSATCRFRGQVDPDGE-----FPLEYWRLITVKLSFVIVFEHFIFILGILLDWLVPDIPKSVEDEIRRE
KLLASKLAQQAKEEDARGDRDRT-------------------------------------
>tr|I1GDN8|I1GDN8_AMPQE Anoctamin OS=Amphimedon queenslandica PE=3 SV=1
----------------------------------------DTDRSDEEERNTVYFNDGVKKIDMILTYKKDDDEDEEGE--P------------------
---------------------SSNAAKRKAFFKKMIEHGLEIERQKPQ-DHQTWFIKVHATFPALEKGAEDLLIRMPIQVDWYRTRC-------------
---FFEPKIPKQF--YKDFFTAPYVAENRQNYRGNNEAEFFSSAQRSTI-WHILENIQYGQTEEQVG----KSDGVFSDSFPLHD------E-IDNERKL
LFNQWSHPKNFYKYQPLENIRHYFGEKIGLYFAWVGFYTSWLGMASIVGIIVMIAGLFTISYNELARDICNNTKEFYMCAPC-ETCDFWYYRSACGFARV
SLLFDFGGTVFFAAFMACWA-LFLEFWKRTEKQLQYDWDTLGFEEAE----QRERPEFVQAIKNKIKDYP-HNDEPK------HHYIPKILLGTSVLLTM
VAAVLG-VLG-LVYRLAVSTSFYRLTQKLGP--ADLTVSITGSLIQLIFIVIMNQVYERLAAWLTSWELHRTTTEYEDSFTFK---FQFINFYSSIFYIA
FIKG--TGYPGGYL------RLDECSAYGCLLELTIQLAIIFLGKQVL-NNVTELGIPYFKTIIKKYMRRRKEK-IVEEEDNKFLRWEKDYELVPLHGLF
FEYLELVIQYGFVTIFVAAFPLAPFFAWVNNVIEIRLDAHKFVTVFRRPLAERAGDIGIWFHLLRFVTNLSVVTNALLIAVTSQFIDRELFDRVYKDNSG
DGSYARWATSEFQFTNLLRSVDDSGKTTFPKNETTCRFRGQVNEDGT-----HPLTYWHLWTCKLAFIIVFEHFIFILGILLDWLVPDIPKSVEDEIRRE
RLLASRMSAETKKKGTGGKGGSK-------------------------------------
>tr|F1PQ46|F1PQ46_CANLF Anoctamin (Fragment) OS=Canis lupus familiaris GN=ANO6 PE=3 SV=2
-------------------------------------------EEFNGKHDSLFFNDGQRRIDFVLVYEDESRKETNKKG--------------------
---------------------EKQRRKRQAYESNLICGGLQLEATRS-LDDKLIFVKVHAPWEVLCTYAEIMHIKLPLKND-------------------
---VLQVDESII---EQEFFTAPFEKN----FYIHDRDTFFNPATRSRI-YFILSRIQYQVR-----INKLVSSGIYKAAFPLHD----RSPSCPSERYL
LYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLFLAAIVGVACFLYGYVNQN---C-KEVCHPDGKIIMCPQCDKICPFWKLNSTCESSKK
LCIFDSFGTLVFAVFMGVWV-LFLEFWKRRQAELEYEWDTVE-L--Q-------RPEYEAQC---------INEEPFT---TW--KCIRV-LCASAVLFW
ILLIIA-VIG-IVYRLSVLVVFSTKSQTFTD--PQTATSITASVISFIIIMILNTIYEKVAIMITNF--PRTQTDYENSLTMK---FQFVNYYSSCFYLS
CFMF--TGHPTK-SFFTNKYKIFQCEPGGCLLELTTQLTIIMGGKAIW-NNIQEVLLPWIKNLIG-----RY--HASRTEKK-SPRWEQDYHLQLMLGLF
YEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKMTTQYRRMVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYPPYGN-YT
MEGYINSTLSYFNVSDFKSRSRGSSA-----------YRDFRNPPGHPQEYKHNIYYWHVITAKLAFIIVMEHVIYSVKFFISYAIPDVSKRTKSKIKRE
KYLTQKLLHENHLKDMTKTMGVI-------------------------------------
>tr|G3QQA7|G3QQA7_GORGO Anoctamin (Fragment) OS=Gorilla gorilla gorilla GN=ANO6 PE=3 SV=1
-------------------------------------------EEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKG--------------------
---------------------EKQRRKRQAYESNLICHGLQLEATRS-LDDKLVFVKVHAPWEVLCTYAEIMHIKLPLKND-------------------
---VLSVDESII---EQEFFTAPFEKN----FYIADRDVFFNPATRSRI-YFILSRVKYQVI-----INRLVNSGIYKAAFPLHD----QSPSCPNERYL
LYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQD---C-KEVCHPDGKIIMCPQCDRLCPFWKLNITCESSKR
LCIFDSFGTLVFAVFMGVWV-LFLEFWKRRQAELEYEWDTVE-L--Q-------RPEYEARC---------INEEPFT---AW--KCIRI-LCASAVFFW
ILLIIA-VIG-IVYRLSVFIVFSAKPKNITD--PQTATSITASIISFIIIMILNTIYEKVAIMITNF--PRTQTDYENSLTMK---FQFVNYYSSCFYIA
FFKG--VGYPGDPVYWLGKY-NEECDPGGCLLELTTQLTIIMGGKAIW-NNIQEVLLPWIMNLIG-----RF--HVSGSEKI-TPRWEQDYHLQPMLGLF
YEYLEMIIQFGFVSLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNYIIIFNCQDLLYRYCYCIQYEE-FS
LSAYILQLRPLFKWGLCLQYSGKKIC-------FVFRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFIIVMEHVIYSVKFFISYAIPDVSKRTKSKIQRE
KYLTQKLLHENHLKDMTKNMGVI-------------------------------------
>tr|A0A0N5DHN5|A0A0N5DHN5_TRIMR Anoctamin OS=Trichuris muris PE=3 SV=1
----------------------------------------SRSQGWSKRLNNGFNEGQYPRTDYVLVYNM------------------------------
---------------------SQDEERRNFFEDHLEDEGLQLDRVIEDDGKKYCFVLIHAPWDFLIRQAEVLKMRMPVRNDGWL----------------
-------TIVADT--NRHYFTALFRRDKLDQF-MENQETFFTSAQRSYM-FDILARTEFDVQR----ILRLLNAGTYCAAYPLHE----GPDKPLSDRQE
LFRRWANIKRWWDYQPYDLIRRYFGEKIALYFVWLGHYTVCLFPISILGILCVVYGFWTLN-DIPSKEICN--SDLMMCPNC-VGCDFWKLGSSCTYARV
THLFDNGCTVLFAALMSLWA-LFLEAWKRRQGELSWRWNLCDFDLEE----DVIRPEFEICAK---K----LNMEPF------SERVLRLIASSVTVLFC
LCLVLA-TFS-ILYRIIVSHHFDRHETTYVR--ASVVASFSAALLNLLIVMILDQAYAKLAWRLTNWEFPRTESEFENSYTFK---FQFINYYSSLFYIA
FFKG--AKLPGP-------TRPEACDPNGCMVELLIQLAIIMVGKQFI-NNVMEIGVPMMYNYLRKKKS------TGTAALTSAMAWARDFLLNPVDFLL
GEYLEMILQYGFVTLFVAAFPLAPAFALLNNIIEVRLDAYKYVVTYRRPLPSRTKDLGVWMHILVGISRMAVLTNACVIAFTSDFVPRMVYRHLFSTNSS
LEGFVGGELSMFNPFSFC-R----------CNLTSCRYEDYRKPPCTADSYSTNTKWWIVLAMRILFVLLFENLVFTVKMLFEWFVPDLPFKVHVQIQRE
KYLAKQALYDNAFKEQSPKHLSR-------------------------------------
>tr|A0A085N7G8|A0A085N7G8_9BILA Anoctamin OS=Trichuris suis GN=M514_22454 PE=3 SV=1
----------------------------------------AKSERSFERLTNGFNEGEQLRVDYVLVYNI------------------------------
---------------------SHDDERRNFFEEHLEDEGLILERVTEEDGTKYCFVLIHAPWEFQVRQAEVLKMRMPVRNDGWL----------------
-------AIVADV--SRHYFTAMFRGDKLNQF-LEDKETFFTSAQRSRM-FDILARTEFDVQR----ILRLLNAGTYCAAYPLHE----GPKEPPSDRQL
LFKGWANFARWWDPQPYERIKRYFGVKIALYFVWLGHYTACLTPVSILGVLCVLYGFWTME-DVPSKDICT--SELMMCPNC-VGCDFWKLGSSCTYAKA
TYLFDNTCTVIFAALMSLWA-LFLEAWKRRQGELSWRWNLCDFDLEE----DVVRPEFEICAK---K----LNMEPF------SERVLRLIASGVMVLFC
LCLVLA-TFS-ILYRIIVSHHFDRHETTYVR--ASVVASFSAAILNLIIVMILDQAYARLAWRLTNWEFPRTESEFENSYTFK---FQFINYYSSLFYIA
FFKG--AKLPGP-------TRPEACDPNGCMVELLIQLAIIMVGKQFV-NNIMEICLPLLFNYMRKK-S------PKTAKLASAADWVNDFLLNPVDFLL
GEYLEMILQYGFVTLFVAAFPLAPAFALLNNIIEVRVDAYKYVVSYRRPLPARAKDLGVWMHILVGISRLAVITNACVIAFTSDFVPRMVYRHFFSANGS
LTGYLNEELSMFNPFMFC-R----------CNLTSCRYEDYRKPPCTADGYSMNTKWWIVLAMRILFVLVFENLVFVVKMFFEWFVPDLPFKVHVQIQRE
KYLAKQALYENAFKQQTRKKRST-------------------------------------
>tr|A0A096N448|A0A096N448_PAPAN Anoctamin (Fragment) OS=Papio anubis GN=ANO5 PE=3 SV=1
----------------------------------------LMFQKNQQSKDSIFFRDGIRQIDFVLSYADDIKKDAELKA--------------------
-------------------------ERRKEFEKNLRKTGLELEIEDKRAPGKIYFFYIYPSPCSLLLLLTVYGKRKIIPDD-------------------
---EILAQ-------KEEVWTGTINYD----LPSIIRACIYIQCRHFKI-YYILSRCPFGIE-----IERLLNSNTYSSAYPLHD----PSPNPTNERYI
LHQNWARFSYFYKEQPLDLIKNYYGEKIGIYFVFLGFYTEMLSFAAVVGLACFIYGLLSME---NSTEICDPEGQMIMCPLCDQVCDYWRLNSTCLASKF
SHLFDNESTVFFAIFMGIWE-LFRKYWKQRQARLEYEWDLVDFEEEQ-------RPEFEAMC---------LNMEPLY-------RIPWY-LSGATVTLW
MSLVVT-MVA-IVYRLSVFATLASFESDALK--PQITTSLTGSCLNFIVILILNFFYEKISAWITKM--PRTYQEYESSLTLK---FQFVNFYSSCFYVA
FFKG--VGYPGKYTYLFDKW-SEECDPGGCLIELTTQLTIIMTGKQIF-GNIKEAIYPLALNWWRRRK-------RTNSEKL-YSRWEQDHDLESFLGLF
YEYLETVIQFGFVTLFVASFPLAPLLALINNIVEIRVDAWKLTTQYRRTVASKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYYYAYST-QP
MKGYVNNSLSVFLIADFPNHTAPSEKRDF-T----CRYRDYRYPPDDENKYFHNMQFWHVLAAKMTFIIVMEHVVFLVKFLLAWMIPDVPKDVVERIKRE
KLMTIKILHDFELNKLKENLGIN-------------------------------------
>tr|I3N1J6|I3N1J6_ICTTR Anoctamin OS=Ictidomys tridecemlineatus GN=ANO6 PE=3 SV=1
----------------------------------------PTQEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKG--------------------
---------------------EKQRRKRQAYESNLICQGLQLEATRS-LDDKIVFVKVHAPWDVLCTYAEIMHIKLPLKND-------------------
---VLRVDERLI---EQEFFTAPFEKN----FYIVDKDSFFNPATRSRI-YFILSRVKYQVV-----INRLVSSGIYKAAFPLHD----RSPSCPNERYL
LYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQD---C-KEVCDPDGKIVMCPQCDKICPFWKLNITCESSKK
LCIFDSFGTLVFAVFMGVWV-LFLEFWKRRQAELEYEWDTVE-L--Q-------RPEYEAQC---------INEEPFT---AW--KCIRV-LCASAVLFW
ILLIIA-VIG-IVYRLSVFIVFSAKPSTVTD--PQTATSITASIISFIIIMILNTIYEKVAIMITNF--PRTQTDYENSLTMK---FQFVNYYSSCFYIA
FFKG--VGYPGDPVYWLGKY-NEECDPGGCLLELTTQLIIIMGGKAIW-NNIQEVLLPWIMNLIG-----RY--HVSGSEKK-TPRWEQDYHLQPMLGLF
YEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRMVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYPPYGD-YT
MEGYISNTLSIFNIADFKNKSKGDSF-------TTCRYRDFRNPPGHPQEYKHNIYYWHVIAAKLAFIIVMEHIIYSVKFLISYIIPDVSKSTRSKIKRE
KYLTQKLLHESHLKDMTKNMGAI-------------------------------------
>tr|I3MP31|I3MP31_ICTTR Anoctamin OS=Ictidomys tridecemlineatus GN=ANO5 PE=3 SV=1
----------------------------------------LMFQKRAQSKDSIFFRDGVRQIDFVLSYVDDIKKDAELKA--------------------
-------------------------ERRKEFEQNLRKTGLELEIEDKREDGRTYFVKIHAPWEVLVTYAEVLGIKMPVKSD-------------------
---PVRLPQEVK---RPEYFTAQFSRH----FLIEDEATFFPSSSRNRI-YYILSRCPFGVE-----IDRLLTSNTYSSAYPLHD----PAPSTVNERYT
LYQNWARFSYFYKEQPLDLIKDYFGEKIGIYFVFLGFYTEMLLIAAVVGLACLIYGILLMD---NSIDICDPEGQLIMCPLCDQVCDYWRLNSTCLISKL
SHLFDNESTVFFAIFMGIWV-LFLEFWKQRQARLEYEWDLVDFEEEQ-------RPEFEAMC---------MNLEPLW-------RIPWY-LSGATVTFW
MALVVS-MVA-IVYRLSVFATFASFESEALQ--PQLATSLSGSCLNFIVILILNFFYEKISAWITKM--PRTYQEYESSLTLK---FQFVNYYSSCFYVA
FFKG--VGYPGKYTYLFNVW-SEECDPGGCLIELTTQMTIVMTGKQIF-GNIKEAIYPLVFNWWRRRK-------RTNSEKL-YSRWEQDHDLETFLGLF
YEYLETVIQFGFVTLFVASFPLAPLLALLNNIIEIRVDAWKLTTQYRRPVAAKAHSIGVWQDILYGMAVVSVATNAFIVAFTSDIIPRLVYYYAYST-HP
LKGYVNNSLSVFLIADFPNHTAPSEKREF-T----CRYRDYRNPPEDKDKYIHNMQFWHVLAARMTFIIVMEHVVFLVKFLLAWMIPDVPKDVEERLKRE
KLMTVKILHDFELKKLKENLGIN-------------------------------------
>sp|Q75UR0|ANO5_MOUSE Anoctamin-5 OS=Mus musculus GN=Ano5 PE=2 SV=1
----------------------------------------LMFQRSEHSKDSVFFRDGIRQIDFVLSYVEDLKKDGELKA--------------------
-------------------------ERRREFEQNLRKTGLDLETEDKLEDGKTYFVKIHAPWEVLVTYAEVLGIKMPIKSD-------------------
---AVKLPSSVK---TPEYFTAQFSRH----FLIEDEATFFPSSTRNRI-YYILSRCPFGVE-----IERLLNSNTYLSAYPLHD----PS-TRPNERYN
LCKNWARFSYFYKEQPFHLIRNYFGEKIGIYFVFLGYYTEMLLFAALVGLACFIYGLLSME---NSTEICDPDGQMIMCPLCDEVCDYWRLNTTCLHSKF
SHLFDNESTVFFALFMGIWV-LFLEFWKQRQARLEYEWDLVDFEEEQ-------RPEFEAMC---------MNMEPLC-------RIPWY-VSGTTVTFG
MALLLS-MVS-LIYRLSVFATFASFESEALQ--PQLATALSGSCLNCIVILILNFFYEKISAWITKM--PRTHQEYESSLTLK---FQFVNYYSSCFYVA
FFKG--VGYPGSYTYMFNIW-SEECGPAGCLIELTTQLTIIMIGKQIF-GNIHEAFQPLIFNWWRRRR-------RTHSEKL-YSRWEQDHDLQVYRGLF
YEYLETVIQFGFATLFVASFPLAPLFALMNNIMGIRVDAWKLTTQYRRPVAAKAHSIGVWQDILFGMAIVSVATNAFIVSFTSDIIPRLVYFYAYST-EP
LSGYVNNSLSVFLIADFPNHTVPMEKKDF-T----CRYRDYRYPPDHEDKYSHNMQFWHVLAAKMTFIIVMEHVVFLFKFLLAWLIPDVPKDVVEKIKRE
KLMTIKIIHDFELNKLKENLDVE-------------------------------------
>tr|G3T7Y2|G3T7Y2_LOXAF Uncharacterized protein (Fragment) OS=Loxodonta africana GN=ANO5 PE=4 SV=1
----------------------------------------LMFKKCLQSKDSIFFRDGVRQIDFVLSYVDDIKKEGDIK---------------------
------------------------VERRREFEINLRKTGLELETEDKREDGKTYFVKIHAPWEVLITYAEVLGMKMPIRSD-------------------
---PLKLKKAVK---HPEYFTAQFTRH----FLIEDESTFFPTSARNRI-YYILSRCPFGTE-----IERLLNSKTYSSAFPLHD----PSPSPVNERYI
LHKNWARFSYFYKEQPLNLIRRYYGEKIGIYFVFLGFYTEMLSYAAVVGLACFIYGLLSME---DSREICDPEGQILMCPLCDQLCDYWRLNTTCLASKF
SHLFDNESTVFFAIFMGIWV-LFLEFWKQRQAKLEYEWDMVDFEEEQ-------RPEFEAMC---------LN-EPLC-------RIPWY-LSGATVALW
MSLVIA-MVA-IVYRLSVYATFATVESEALE--PQLTTSLTGSCLNFIVILILNFFYEKISAWITKM--PRTYQEYESSLTLK---FQFVNYYSSIFYVA
FFKG--VGYPGKYTYMFNIW-SEECDPAGCLIELTTQLTIIMFGKQIF-GNVKEAIYPLALNWWRRRK-------RTNSEKL-YSRWEQDHDLESFLGLF
YEYLETVIQFGFVTLFVASFPLAPLLALLNNIIEIRVDAWKLTTQYRRPVASKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYFYAYST-DP
LKGYINNSLSVFLIADFTNRTAPAEKRGI-T----CRYRDYRYPPEHESKYSPNMQFWHVLAAKMTFIIVMEHVVFLVKFLLAWMIPDVPKDVVERIKRE
KLMTVKILHDFELNKLKENLRLN-------------------------------------
>tr|H0WNM0|H0WNM0_OTOGA Anoctamin OS=Otolemur garnettii GN=ANO5 PE=3 SV=1
----------------------------------------LMFQKLKQSRDSIFFRDGIRQIDFVLSYVDDAKKDAEIKA--------------------
-------------------------ERRKAFEQNLRKTGLELETEDKKEDGRTYFVKIHAPWEVLLTYAEVLGIKMPIKSD-------------------
---AVRLPPNVK---HPEYFTVQFSRH----FLMDDPSKFFPSSTRNRI-YYILSRCPYGIE-----IERLLNSNTYLAAYPLHD----PSPNPVNERYI
LYQNWARFSYFYKEQPLDLIRNYYGEKIGIYFVFLGFYTEMLLVAAVVGLGCFIYGLLSMN---NSMEICDPQGQMIMCPLCDVLCDYWRLNSTCLASKI
SHLFDNESTVFFAVFMGIWV-LFLEFWKQRQARLEYEWDLVDFEEEQ-------RPEFEAMC---------INLEPLR-------RIPWF-CSIATVVLW
MALVLS-MVA-IVYRLSVFATFASFEKDALK--PQIATSLTGSCFNFIVILILNFFYEKISAWITKM--PRTYQEYESSLTLK---FQFVNYYSSCFYVA
FFKG--VGYPGKYTYMFNVW-SEECDPGGCLIELTTQLTIIMIGKQIC-GNVKEAIYPLVLNWWRRRK-------RTNTEKL-YTRWEQDHDLESFLGLF
YEYLETVTQFGFVTLFVASFPLAPLFALLNNIVGIRVDAWKLTTQYRRTVASKAHSIGIWQDILFGMAVLSVATNAFIVAFTSDIIPRLVYYYAYST-HP
MRGYVNNSLSVFLIADFPNHTVPSGKQDF-T----CRYRDYRHPPDNDRKYFHNMQFWHVLAAKMTFIIIIEHIVFLVKFLLAWMIPDVPKDIEERIKRE
KLMTIKIIHDFELKKLKEHLGID-------------------------------------
>tr|H0VPW8|H0VPW8_CAVPO Anoctamin OS=Cavia porcellus GN=ANO5 PE=3 SV=1
----------------------------------------LMFQKSKQSKDSIFFRDGIRQIDYVLSYVDDIKKDADIKA--------------------
-------------------------ERRKEFEQNLRKSGLELEIEDKREDGRTYFVKIHAPWEVLATYAEVLGIKMPIQSD-------------------
---PVKLPESVK---RPEYFTVQFNRH----FLIDDKSTFFKSSSRNRI-YYILSRCPFGVE-----IERLLNSNTYSSAYPLHD----SSPNPVNERHI
LYKNWARFSYFYKEQPLDLIRDYYGEKIAIYFVFLGFYTEMLFIAALVGLACFIYGLLSMN---NSMEICDPNGQMIMCPLCDQVCDYWRLNTTCWASKF
AHLFDNESTVFFAIFMGIWV-LFLEFWKQRQARLGYEWDLVDFEEEQ-------RPEYEAMC---------MNMEPLF-------HIPWY-LSGATVTLW
MALVVT-MVA-IVYRLSVFAAFASFESDTLQ--PQLATSLTGSCLNFIVILILNFFYEKISAWITKM--PRTYQEYESSLTLK---FQFVNFYSSCFYVA
FFKG--VGYPGKYTYLFNVW-SEECDPGGCLVELTTQLTIIMIGKQIF-TNIKEAIYPLVFNWWRRRK-------RTNSEKL-YSRWEQDHDLQSFLGLF
YEYLETVIQFGFVTLFVASFPLAPLFALMNNIVEIRVDAWKLTTQYRRPVAAKAHSIGVWQDILAGLAVLSVATKAFIVAFTSDIIPRLVYYYAYST-EP
LAGYVNNSLSVFLIADFPNHTVPLDKRDV-T----CRYRDYRNPPGDENKYLHNMQFWHVLAAKMTFIIIMEHIVFLVKFLLAWMIPDVPKDVVDRIKRE
KLMTVRILHDFELNKLKEKLGLN-------------------------------------
>tr|F6ZLF5|F6ZLF5_XENTR Anoctamin OS=Xenopus tropicalis GN=ano4 PE=3 SV=1
----------------------------------------VLSAPEKNKTSGLFFNDGKRRIDYILVYRKTSLQ--------------------------
------------------------SEKREIFERNIRAEGLHLEKES--VNSDIIFVKLHAPWEVLGRYAELMNVRMPFRRK--------FM-------SR
MEKPMRLDKEKIP--ENDCYTAPFSQQ----FIINNKDTFFNNATRTRI-HHILQRVKYEEG-----LNRLLTNCTYEAAFPLHE----KNHGAENHRHL
LFECWASWGVWYKYQPLDLV-RYFGEKIGLYFAWLGWYTGMLFPAAIVGLFVFLYGMFTLD---CSREICQA-TNITMCPLCDKYCPYMRLSDSCIYAKV
THLFDNSATVFFAVFMAVWA-PVLAFQSTVKGQP--------------------RPQFEA------KY---VNPEAFA-------KCSRL-VSASGIFFM
ICVVIA-VFG-VIYRVVTVSTFAAFWALI-N---QVATTGTAVCINFCIIMLLNVLYERVALFLTNL--PRTESEWENSFTLK---FQFVNLNSSTFYIA
FFLG--TGRPGAYLRLIN--RLEECHPSGCLIDLCLQMGIIMVLKQTW-NNFMEG-YPLIQNWWTRRKLRQEH----IHGKTALPQWEKDYNLQPIYGLF
EYFLIT-LQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFITQWRRPLASRAKDIGIWYGILEGIGILSVITNAFVIAVTSDFIPRLVYAYKYGP-KC
MVGYVNASLSVFLVTDFENHSNSSRNGREFQYVKYCRYRDYRDPPSAPEPYAYTLQFWHVLAARLAFIIVFEHLVFFIKHLISYLIPDLPKDLRDRMRRE
KYLIQEMMYEAELERVQKEKKER-------------------------------------
>tr|A0A087XW87|A0A087XW87_POEFO Anoctamin OS=Poecilia formosa GN=ANO4 PE=3 SV=2
----------------------------------------VPEVDRRNKSSGLCFGDGKSLIDYILVYRKSSSQ--------------------------
------------------------SEKREMFERNIRAEGLRMEKE---TNSDVIFLKLHAPWDVLCRYAELMNIRMPFRRK--------FL-------SR
MEKPMKFDNDTLP--ENESFTAPFSRS----FIIHNKDTFFNNATRSRI-HHILQRVKYEEG-----LNRLLTNNSYDAAFPLHE----KNHGAENHRHL
LYECWAWWGVWYKYQPLDLI-RYFGEKIGLYFAWLGWYTGMLFPAAVVGLFVFLYGVFTLE---CSKEICQA-TDTIMCPICDQYCPYLRLSDSCIYAKV
THLFDNGATVFFAVFMAVWA-VFLEFWKRRRAVLAYDWDLIDWEEEE-------RPQFEA------KY---MNPEAFT-------KYSRL-VSSSGIFFM
ILVVIA-VFG-VIYRVITVSTFAAFWALI-N---QVATTGTAVCINFCVIMLLNVLYERVALFLTNL--PRTESEWENSFTFK---FQFVNLNSSTFYIA
FFLG--TGRPGAYLRLIN--KLEECHPSGCLIDLCMQMGIIMVLKQTW-NNFMEG-YPLIQNWWTRQRLKREH----HIPKASLPQWERDYNLQSMYGLF
D--LKM-LQFGFTTIFVAAFPLAPLLALINNIIEIRLDAYKFVTQWRRPLPSQAKDIGIWYGILEGIGILSVITNAFVIAVTSDFIPRLVYAYKYGP-GC
MMGYVNASLSVFRVSDFEKRSQPRTNGSELEAVKYCRYRDYREPPDSPEPYTYTLQFWHVLAARLAFIIVFEHMVFAIKTLIAYLIPDLPKDLRDRMRRE
KYLIQEMMYEAELERLQKEKDEK-------------------------------------
>tr|I3JNJ0|I3JNJ0_ORENI Anoctamin OS=Oreochromis niloticus GN=ano3 PE=3 SV=1
----------------------------------------SVQGKNPTASSGLFFRDGKKRIDYILVYKKSSPQ--------------------------
------------------------VEKRCTFEKNLRAEGLMLEKE---TNNDIMFVKVHATWDTLCKYAEQMNIRMPFRKK--------TLGS-----MQ
TSMPMKLDKEALP--ETDCYTAPFSRA----FTINNRETFFSNSTRSRI-HHVLQRTKYEDG-----INRLLGNSTYEAAFPPHE----RHHGAQNHRHL
LYERWARWGMWYKYQPLDLI-RYFGEKIGLYFAWLGWYTGMLIPAALVGVFVFLYGLLTMD---SSKEICEA-NTTIMCPMCEENCEPWTLSDSCVYAKV
TYLFDNGGTVFFAIFMAIWA-VFLEFWKRRRAELTYDWDLIDWEEEE-------RPQFEA------KY---VNPEPFS-------KLSRL-VSVSGIFFM
ISLVLT-VFA-VVFRLIAMEKFASFWHFV-K--QF-ATSGTGVCINFMIIMSL-VVYEKVAYLLTNL--PRTESEWENSFALK---FQFVNLNSSTFYIA
FFLG--AGRPGKYNKLFS--RLEECHPSGCLIDLCLQMGVIMFFKQIW-NNFMEG-YPLLQNWWSRRKMKKGG-GQNVENKAQLPQWDKDWNLQPMHGLV
D--LEM-LQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPMPARATDIGIWHGILEGIGVLAVITNAFVIAITSDYIPRFVYAFKYGPNEC
LQGYVNSSLSVFDMGELNN-RN--H-------SGYCRYRDYRAPPWNTVPYEFTLQFWHVLAARLAFIIVFEHLVFGIKSFIAYLIPDMPKDLCDRMRRE
KYLMQEMMYEAELEHLQKERK---------------------------------------
>tr|U6P3S7|U6P3S7_HAECO Anoctamin OS=Haemonchus contortus GN=HCOI_01117700 PE=3 SV=1
----------------------------------------FFALEWD---KNCYFSDGKRQIDYVLAYEDDSANGTTSTDGST-----------------
-P--AE----------I----EKKRTRRFNYECNLQRMGLQIERVSISTLGRTRFVLLHAPFALLEKQAQLLSVKLPVQSDGFV----------------
---DFDERVKKVL--EPDFFTAPYSSDRRQQFVNDRPDILFPNAERSRM-YDLLTRAHYDSVT----IERLLAQGVYNAAYPLHQ------GGEVSQREL
LYNHWVSWRNILKYQPLDCIKRYFGTKVAFYFAWLGYYTRSLYVAALLGIIAVLFGIWNLS-DVVSNDICGNDANTIICPQC-NYCDFQLLKNSCLYAKM
SYLFDNGITVIFAALMSVWA-FFLEGWKRYHAEIAWKWGLLDFVVEE----DTVRPDFQFRVK---T----YNEESG------KKKFANFCAGGVTVLFF
MCLVLA-VFG-VVYRVICMRLLASMDNPTVD--AFLIVSSTAASINLSIILCMNYFYNSLAHRLTRWECPRTQADFDNSYTFK---FQFANYYSSLFYVA
FFKG--SQLPGT-------KRLEGCDPAGCFVELVIQLAIIMCGKQFF-SALVEFAYPNFMRLLRRWQLMVPIVETNKKAGHVMNRWEADYYLNPTQFLF
DEYLEMVLQFGFVTLFVAAFPLAPLFAVLNNIFEIRLDAYKFLLTIQKPVPAQAKNIGVWLSILDMISKFTVPINALVIAFTSDFIPRTLYLLAN---SS
MIGYVDSSLSYFDATDFDIK----------HNVTQCRYRGFRRSPCSLDHLGYSLVWWKVFAARLLFVVIFEHIVFVIKLLIEYLIPDVPARIFVQQQRE
KYLVRKALLSELVSGKSSANGPS-------------------------------------
>tr|A0A0R3PYK7|A0A0R3PYK7_ANGCS Uncharacterized protein OS=Angiostrongylus costaricensis PE=4 SV=1
----------------------------------------FFALEWD---NHCYFSDGKRQIDYVLAYEDDFQIDVI-NDSAS-----------------
----L-----------T----EKKRIRRFNFETNLEKMGLQIERANISMLGRTRFVLLHAPFSVLEKQAQILSVKLPVQSDGFL----------------
---DFNERTRKAL--EPDFFTAPYSSDRRKQFVNDRPDILFPNSERSRM-YDLLTRAHYDDVI----IERLLSQRAYSAAYPLHQ------GKELSQREL
LYNHWASWRNIFKYQPLDCIKRYFGTKVAFYFAWLGYYTRTLYLAAIVGVISVIYGFSNIS-DIVSNDICGDDTKILICPQC-NYCDFQLLGNSCVYAKM
SYLFDNGSTVVFTALMSVWA-LFLEGWKRYHTEIAWKWGLLDIVIEE----DTVLPEFQFRVK---T----YNEESG------KKKLANFTAAAATVLFF
ICLVLA-VFG-VVYRVICMRLLASMDNPAID--AFLIVSITAAAINLVVIIAMNYFYNSLAHRLTRWECPRTQADFDNSYTAK---FQFANYYSSLFYIA
FFKG--SQIPGT-------KRLEGCDPAGCFVELVVQLATIMCGKQFF-SAFVEFAYPNFMSLMRKWQLMVPLVEHSKKVK-NLTRWEADYYLYPTQFLF
YEYLEMVLQFGFVTLFVSAFPLAPLFAVINNIFEIRLDAYKFLITTQKPVPAQAKNIGVWLSILDVISKFSVIINALVIAFTSDFVPKTMYYLTK---QT
MIGYVDSSLSYFDASAFKLK----------RNVSQCRYRGWRRSPCSLDQLGLSSEWWKVFAARLLFVLIFEHIVFVIKMIVEYLIPDVPTKIFIQQQRE
KYLVRKALLSELAAGRGSANGPC-------------------------------------
>tr|A0A0D8Y2Z7|A0A0D8Y2Z7_DICVI Anoctamin OS=Dictyocaulus viviparus GN=DICVIV_03318 PE=3 SV=1
----------------------------------------FFALEWD---KNCYFSDEKRQIDYVLAYEDDPQYNGVINETPS-----------------
----P-----------F----EKRRIRRYNFEANLQKMGLQIERVNISMLGRTHFVLLHAPFPVLEKQAQILSVKLPVQSDGLL----------------
---DFDERTRKAL--EPDFFTAPYSSDRRKQFVNDKPEILFPSSERSRM-YDLLTRAHYDDLI----IERLLSQGAYSAAYPLHQ------GKELSQREL
LYNHWASWTNILKYQPLDCIKRYFGTKIAFYFAWLGYYTRSLYLAAFIGVVSVFYGFLNIS-DIVSNDICGLDSRILICPQC-NYCDFQLLNSSCIYAKM
SYLFDNGGTVVFAALMSVWA-LFLEGWKRYHAEISWKWGLLDLVVEE----DTVRPEFQFRVK---T----YNEESG------KKKLANFTAGAVTVLFF
ICLVLA-VFG-VVYRVICMRLLASMDNPTID--AFLIVSTTAATINLAVIICMNYFYNSLAHRLTRWECPRTQADFDNSYTFK---FQFANYYSSLFYIA
FFKG--SQLPGT-------RRLEGCDPAGCFAELVIQLATIMCGKQFF-AAVVEFAYPNFMSLLRKWQLMVPIVENSKKMN-HMARWEADYYLNPTQFLF
DEYLEMVLQFGFVTLFVAAFPLAPFFAVLNNIFEIRLDAYKFLITTQKPVPAQAKNIGVWLSILNVISKFSVTINALVIAFTSDFVPKTMYYLSK---HT
MLGYVNSSLSYFDASDFRLK----------HNVSQCRYRGWRRSPCSLDQLGFSSEWWRVFAARLLFVFIFEHVVFVIKIIVEYLIPDVPTKIFVQQQRE
KYWCAKLFYLDLASGRTSMNGPS-------------------------------------
>tr|A0A0N4USF9|A0A0N4USF9_ENTVE Anoctamin OS=Enterobius vermicularis PE=3 SV=1
-----------------------------------------AVVGHG--SSDMYFPDGIRRIDYVLAYSTEDLLERRDSG--------------------
---------------------PPKARKRETYEKNLRSLGLDLLDVEGK-CQNTRFVLIHAPFKLLMKQAETLTVKMPVLSDGVL----------------
---NFDQETNERL--EPNYFTAPFVSSRIKCYVGDNPDTFFDGSERSRM-YDLLIRTKYGEDD----ISRLLQNGAYTAAYPLHE------VKECSNREM
LYWKWAQIGNFYKYQPLSLIKKYFGSKVGIYFAWLGYYTKILMPASLIGFLFFLYGLVTFS-DIPSNDICGSDAEILMCPTC-EYCDFTRLNSSCIYSKL
SYVFDNSSTVFFAAIMSIIA-LFLEGWKRYHAELAWKWGLLDFEIDE----ETVRPEYQVKVKAMKE----FNWEPT------KLRLLRFIGSGVTVLFF
LLLVLA-VAG-IIYRTVLIQVLY--RQDSLQ--ASLLTFSTAAVLNLIVILIMSYVYTFLAYKLTEWECPRTQASFESSYTFK---FQFINYYSSIFYIA
FIKG--SGVPGG--------SPEGCDPAGCMVELVIQLAIIMCGKQFF-SAFVEIALPVLMKIFRTWRFAVGE-KEIRTSSEDIPRYERDYVLNPTQFLF
NEYLEMVIQFGFVTLFVSAFPLAPLFALINNIIEIRMDAYKFTITSRRPMPERAKDIGMWLRILDGISKVAVLVNAFIISFTSDFIPKLVYQWVYN-HDE
LYGYVNDSLSYFDASSLT-V----------QNITVCRFRDYREKPCTLKNYSITTQWWIVLAFRLAFVLVFEHIVFFTKALISYLIPDMPSKIFVQLQRQ
RFLARQARLSNMKTTGNNHPASP-------------------------------------
>tr|F1KT40|F1KT40_ASCSU Anoctamin OS=Ascaris suum PE=2 SV=1
----------------------------------------TRYHSWR--CKPMFFSDGIRRVDYVLAYETKDSTEESSTD--------------------
---------------------EKRASKRHHFEENLCKLGLELEHVEGK-CSNAHFVLVHAPFGLLLKQAENLSVKMPVQSDGML----------------
---TFSEETNERL--EPNYFTAPFITDHLECYVGDDPNSFFETSERSRM-YDLLLRTRYDSEE----IERLMKNGTYTAAYPLHE------VNRCSNREM
LYWNWCRYNNFYKYQPLSLIRRYFGSKIGIYFAWLGYYTKVLFPASVAGVLCFLFGLLTYS-DIPSNDICGSDAVVMMCPTC-KYCAFTPLNASCVYSKL
SYIFDNNATVLFAALMSIGA-LFLEGWKRYHAELAWKWGLLDFEVDE----ETVRPEYQLRVKEART----LNMEPF------RQRILRFFASSITVLFF
LLLVMA-VVG-VVYRIVLLQVLY--RVDGMK--ASILTFTTAATLNLIVILILSYFYTFLALKLTDWECPRTQTEFDNSYTFK---FQFINYYSSIFYIA
FIKG--SSVPGG--------RPEECDPAGCMVELVIQLAIIMCGKQFW-NAFVEIAWPLVRNMVRSWWMGMP--REIECAKAEVPRWERDYVLNPVQFLF
DEYLEMVIQFGFVTLFVSAFPLAPLFALLNNIMEIRLDAYKFLITTRRPLPQRAKDIGIWLPILDGISKAAVLINAFVIAFTSDFVPKFVYRWVYH-HQE
LYGYVNNSLSIYDARS-M-A----------PNITICRFRDYRNPPCSVTEYSVTMQWWIVLTFRLAFVLVFEHVVSAVKAFIAYIIPDMPSKIFIQLQRQ
RFLARQARLSDMGNTASARNAAN-------------------------------------
>tr|H2Y3G9|H2Y3G9_CIOIN Anoctamin OS=Ciona intestinalis GN=LOC100185864 PE=3 SV=1
----------------------------------------LFRELDERPKATLYFHDGVRFIDYVIAYQDNDEHE-------------------------
---------------------DKDDGQRQHYEENLEKAGLMLEREP--QDQNTYFVKVHVPWPILLKYAERMKMKMPLKER----------GCVKTLYRK
LVA-CVLNTEEMT--PD-YYTTEFVRDKMD-FDIQDEKSFFANSQRSRI-HRIMSETRYGPK-----INNLISSGVYECAFPLHE------AINANMRRL
LYWEWARWGRWYKFQPLDLIRLYLGDKVAIYFAWLGYYTEMLFYPTIVGFIVFIYSIIAVWFYAPTQEICDETGNLTMCPLC-EDCSYWKLKTSCLAARI
TYVFDNEATIFFAIFMSLWA-MFLEFWKRRQFELSYEWDLVDYDEQR----DLVRPEFEAQVTK---E---LNMEAA-----KD-KYTRTCLSLVTVFFW
ILVVIA-VFA-IVYRLAISAIFAVSVDL-LG--PAMLTTITASMLSLVIIMCLNKVYEKVAIWLTNMELPRTQTEFEDRFTFK---FQFVNFYSYLFYIA
FFKG--SGTPGHYTY-----RWEQCDAGGCMYELSIQLIIIMFGKQLW-NNFIELVMPWLQHKYRQWKSQKVS---TEMKDNEYTRWEQDYDLNQFMGLF
YEYLEMVIQFGFVTLFVAAFPLAPVLALVNNIIEIRLDANKFICELRRPLAHKCSDIGAWYYLLEFIGNLAVVTNAFTIAITSEAIPKLVYYYVYSL---
--GYVNNSMSYFNTSDFEARSMPNNPDPFGYYFNTCRYPGYLSPPTASPKYEYTTQYWHNIAGKLAFVIVVEHVVFFLKRLLDYLIPDRPRKLRDKIKRE
HFLVQHMLFKAETQQLLKQLSQD-------------------------------------
>tr|K1PYR2|K1PYR2_CRAGI Anoctamin OS=Crassostrea gigas GN=CGI_10003562 PE=3 SV=1
----------------------------------------QAKQQMINEKATLVFRDGKRKIDYVLAYEPEDNE--------------------------
---------------------LKKEQRRNTFEKNLIEEGLELEHEG--KNGKTCFTKVHVPWETMLRYAELLNVKMPLAND------------FENCWKK
FPS-FELDEDLL---PN-YFTAPFNRSRM--FVIKDKDTFFTHAQRSKI-YEILSRAHFLDLD----VRKLVDNQTYNAAYPLHD------VGKDNDRHL
LYELWARPGRWYKYQPLDQIRGYFGEKVGIYFSWLGFYTSMLIPVAIAGVVAFIYGLATIMDDVPSTEICEDPSNYTMCPMC-QRCSYWHLSDSCTYSRA
TYLFDNPATVCFAIVMALWA-FFLEFWKRRQAEIEYEWDVADFEEGE----ETVRPEYEASVSR---R---TNEEPG-----WS-KGFRYFTSFSILLFF
LALVLA-VFS-ILYRIVMSAILYGNS-E-IK--ASFISSISAACINLVIILILNMFYQRVAYFLTELEQHRTLTEWEDAFTFK---FQFVNFYSSIFYIA
FFKG--VGRPGDYNR-----RQEECDPSGCLIELCIQLGIVMVGKQII-NNVKEILIPKLMVWFRSRQSLK-----ETSEEKVYSRWEQDYNLASMLGLF
DEYLEMVIQYGFVTIFVAAFPLAPLFALLNNVIEIRVDAYKFTTQWKRPLAERAQDIGIWFGILRGISAIAVISNAAIIAFTSEFIPKLVYLYGY-S-QT
LSGYTNFSLSEFKVQYFAPQSVPDDPKMEIGNVTQCRYRGYADDPSSPGEYKYTMAYWHILAAKLAFVVVFENLVVFCTWLVMYLVPDMPYKVKLQMLRE
NFLAKEALFSADSIQKQRERKNA-------------------------------------
>tr|R7UV80|R7UV80_CAPTE Anoctamin OS=Capitella teleta GN=CAPTEDRAFT_153854 PE=3 SV=1
----------------------------------------------------MFFRDGQRRIDYILAYHDTDDI--------------------------
----------------------ELISWRDKFEENLKKEGLELETEH--QDGKTHFVKVHAPWDVLTRVAELTKMKMPIKYD------------DTGCLSK
LPN-MLIEDGVI---PE-YFTADFSRERMK-FIIEDQNTFFTNAQRSFI-YELLLRTRYTET-----IDRLIRHAAYSAAFPLHE------ISIGIYLQL
LYETWARPGRWLYFQPTDLVRKYYGEKVGIYFTWLGFYTTMLIPASILGVIVFIYGCATLFKNPPSEEVCDESGNLTMCPLC-RHCSYWKLKTSCMYSRL
TYLFDNGGTVFFACFMAIWA-LFLEFWKRKQAELQYDWDVADFDYEE-----HVRPEFEARCKK---R---LNMEPI-----YS-RIPRWCTSFSVVLFM
ICCVIC-VFG-IMYRVVVVTLLYSVP-N-VQ--ASITTSCTAAVISLIIIMLLNRLYEKVALFLTELERPRTESEYEDSYTFK---FQFINYYSSLFYIA
FFKG--AGRPGDYDY-----RAEECDPAGCLIELCIQLGIVMIGKQAY-NNFKEITLPKIMNWMRSRGAKKN-----ETEENLYTRWEQDYDLNAVMGLF
DEYLEMVIQYGFTTIFVAAFPLAPLCALINNIIEIRLDAYKLTTQMRRSVALRAQDIGIWLNILQGITFMAVLTNAFIIAWTSDFVPKLVYRYTQ-E--T
LDGYVNQSLSFFDVKDFQERSIPKNNASELGDVTYCRYKDQREPPWSPNRYDYTSTHWHTFCAQLAFVIIFEHLVFFLTWLVAYLVPDVPARIRMLMLRE
VYLAKEAKYDASFSTLHSDRRQE-------------------------------------
>tr|H2Z2F0|H2Z2F0_CIOSA Anoctamin OS=Ciona savignyi PE=3 SV=1
---------------------------------------------------MPTFRDGETNIDFILVYSEDDEN--------------------------
---------------------ERHKEMRKTFESHLAKEGMRFETEWL-DHGGTSFIKINASWETLCRWAQISRLKKPFVNDEKV---------SQNDYLT
G---CFKETNYTY--DESFFTATFDKNRLD-FLMESKETFFTKTERYRL-NNILQITSYGEN-----ISQLLSEGAYLDAYPPHE------GSALGPRQT
LYWTWARMGAWARPQPLDLIRLYFGEKIAIYFAWLGFYTMMLIPASILGIVVFLYGVVTLGTEPLVKDICAS--NFTICPLC--TCGFTPLRGSCTYSKI
TYVFDNSGTVVFAFIMSIWA-FFIELWKRYRARLSYRWDTEDFEQEE----DLVRPEYVIVSNK---K---LNMEST-----KI-KARRVAFSVSTLVLM
LLLVIF-LFG-IVYRTITSVLAYQVTKD-IR--IRLIISITASIINFIVITIMDKVYSKLAIKLTNLEAPRTRTEFEDSYTLK---FQAVNYYSSIVYAA
FFKG--AGSPYGYNT-----RLEECDPTGCLIDVCISLAIVMILKQAL-NNTQELLIPIIKSWWARRKVNKGSA--------DDNPTFQDFTLSQFLGLF
SEYLEMVIQFGFITLFVAAFPLAPFFALLNNIIEIRVDAYKFIVQLRRVPPLRGNDIGMWLDILQSISTISVLTNGLVIGITSSFIPKVVYSLLYGPLPC
ISGFLENSLGEIAVQDIRSMNIAVNTS---NSTPSCRFNAFVTPTT--N--PNQINYWHILAGRLIFLLIFEHIVFGLKSFVDIVISDVPSDLAIASRRQ
KLLEIQLFY---------------------------------------------------
>tr|F6YP84|F6YP84_CIOIN Anoctamin OS=Ciona intestinalis GN=LOC100185539 PE=3 SV=2
------------------------------------------------------FRDGKSSIDYILVYKNDDEK--------------------------
---------------------EKHREWRRNFEANLEEEGLRLETVYS-KKNGINFVKIHASWDALCRWAEIGRMKKPFANDKVI---------NRTC---
C---SKDSIKYAY--DESYFTATFDRKRLD-FIMTDRATFFTPTERYRL-HEILRVTGFGED-----MTRLLSDGVYLDAYPPHD------GSNLGPRQA
LYWIWARPGAWARPQPLELIRMYFGEKIAIYFAWLGFYTMMLVPAAVFGIIVFLYGLFSVGGEETVQAVCNS--NLTVCPVC--TCSFDPLKTSCTYSKI
SYVFDNTGTVVFAFVMSIWA-FFIELWKRQRARLSYRWGTQDFEEEE----DLVRPEFIVVSDK---K---LNLEST-----KL-KARGIAFSVSTLFFM
LVLVVI-LIG-IVYRTISSVLAYQATSG-IQ--IRLIISITASIINFIIITILDVIYNKLALKLTNLEAPRTRTEFEDSYTLK---FQAVNYYSSTVYAA
FFKG--AGSPYRYHT-----RLEECDPTGCLIDVCINLAIVMILKQAL-NNTKELLIPVISSWLARRKAKKAQN--------P--NAENDYPLSKYLGLF
SEYLEMVIQFGFITLFVAAFPLAPFFALLNNIIEIRLDAYKFVTQLRRVPPLRCNDIGMWLSILQSISTISVLTNGLVIGITSSFIPKTVYSLLYGPSSC
LSGFIDSSLGEIGVKNISVMNHIAHNF---LLPETCRFRAFPTPILNSN--TNQLNYWHVFAGRLIFLLIFEHIVFGLKTIVDLLISDVPTDLAIASRRQ
KLLEVRMFYNQVSLRLGKIYPRR-------------------------------------
>tr|V3ZDU0|V3ZDU0_LOTGI Anoctamin (Fragment) OS=Lottia gigantea GN=LOTGIDRAFT_106472 PE=3 SV=1
----------------------------------------------------LYFQDGKRRIDFVLTYRDDDKDKEKDKK--------------------
------------------------IARRKFFEDNLIKDGLELEYEERAKADKVRFVKVHCPWEVLTTYAEIMSMKMPLAND-------------------
---PFDVDEDYL---VPDYFTAAFSRS----FVIEDQETFFSSAQRSLI-NEVLSRCVYETTVS---IKNLVNAGVYTAAFPLHE----PHKGKANDRHL
LYETWARPGRWYKFQPLDHIRKYFGEKIGIYFAWLGYYTGLLIPAAMVGLAVFLYGCIQMF---DQEEICDENGNVTMCPLCDERCTYWKLKKSCLYTRA
TYLFDNEATVFFAAFMALWA-FFHEMWKRKQAEIEYDWDVADFEE-E-------RPEFEAQV---------MNDERFL-------KLARF-SSFTVVIFM
LLLVVA-AFG-ILYRVTVAAIFYSVQEDI----ANLLTTVTAAIINLIIIVILSMVYLRIAEFLTNF--HRTETEWEDSFTFK---FQFINHYSSLFYIA
FFKG--LGRPGKYNRELNGK-QEECDPAGCLIELCIQLAIVMVGKQAL-NNFKEIILP-IMNLYKTWG------K---QKQK-LPRWEDDYNLAVMLGLF
DEYLEMVIQFGFVTIFVAAFPLAPLFALINNIIEIRLDAYKFVTQWRRPLAVRGQDIGIWFGILRGISTIAVITNSVIIAFTTEFIPKLVYVY--GY-EN
LHGYVNFSLSTFKVKDFEDESRPANNNSEVLFLNCFRYRDFRD----KDNYNFDMDFWHVLAARLAFALIFILLVFFFSWLVSYIVPDIPKTVKLQVLRE
KYLAKEAIMEAESLRRRKNDKNG-------------------------------------
>tr|Q1AP37|Q1AP37_STRPU Anoctamin OS=Strongylocentrotus purpuratus PE=2 SV=1
------------------------------------------AKKDDNKVNDLFFKDGKRRIDFVLAYRKQESE--------------------------
---------------------EKRVKKRQNFEANLIDEGLQLEYENSEHDGRTFFVKVHAPWDLMTRYAEELKIKMPIENN------------VFNCIDK
LWT-FELSEEYV---PD-VFTAPFIRDRAS-FIMESQDTFFPNNIRNRV-YEILERMRYDAND----IDHLIANGSYFAAYPLHE------HGPQNDRHL
LYEEWARSGRWYKKQPLDLIRCYFGEKIGIYFCWLGFYTEMLTWAGFVGLIVFLYGCISLPSSVVVQEICAGT-DIIMCPLC-KRCPYWTLSDSCFYSKL
TYLFDNEATVFFACFMSLWA-MFCEFWKRRQNTIDYDWDLFGFEEQE----ENIRPEFEAKAPD---R---VSPEKF-----SK-RFPRFSTSVPTIAFM
ILLVMA-VMT-IVYRIVVKTAIFAID-Q-IS--ASIITSVTASMISLILIMILQILYERIAVWLTNLELHRTETEYEDSFTFK---FAFVNYYSTSFYIA
FFKG--PGTPADYGR-----RQEECDPAGCTQELFINIAITMCGKQFF-NNFMELAMPVLMNFWRSRTGRKE----EKSGKGRYEQWEQDADLADLRGLF
KEYLEMVVQFGFSTIFVAAFPLAPLFALLNNLVEVRLDAYKFISQLRRPVAKRAQDIGAWYAILVTVGNLSVLTNALVIAFTSEFIPRQVFKYYYGG-AT
LNGYTNWSLSYFNTVDMQNDSKPTDPSYPRLNVSVCRYRGN------DEHYNVTLDYWLVIAIKLAFILLYEHFVLFTKFFVAYIIPDMPEFVKNQIKRE
TYLGQQALRTALTEQRGKSKKLV-------------------------------------
>tr|A0A0A9Y8D0|A0A0A9Y8D0_LYGHE Anoctamin OS=Lygus hesperus GN=ANO5_1 PE=3 SV=1
----------------------------------------QVKPAKWN-EGVSHFEDHVRTVDYVLAWDTSITPS-------------------------
---------------------PFPENKREVYQRNLIGEGLELEEDHEYNVSTLKFIKIHVPKNTMANYAEILKFRQPIREL----K-SIRRKTYLQL---
-LGHIYVDSSTFP--VGFRYSTTYSRDKHYLFDD-DEDNFFTPTSRARV-HFILDRTEFEEPP----ISRLINLGVYTAAYPLHD--------G-TLRHT
LLNEWGSVKRWYRYQPLDYIKDYFGVKVALYFCWLGFYTCMLFPAAIIGLIVFLSGFIHV-SSVLTKEVCDDGDKTIMCPLC-KFCDFWFLNQSCTYSTI
LSVFDNGTTVFFAAFMSIWA-LFLELWKRYSAEVTHRWDLTGYDTHE----EVARPQYLARVERYYTMK---NDEPY-----WTVKLPATFFSFSVVALL
VILAVV-CVG-IVYRMAMITASAFYGVDVLS--ALVIINITAGVLNLIALMVLTWLYDWVALVLTEFEMVRTQSEFDDSLTFK---LQFINYYTSIFYLA
FIKG--IGYPKQYT------RQEECDTGGCLFEVTAQLAIIMVGKQVT-STFLELVYPVLMKYWRAGFKKQYWK----LWGEEGPQWVQDYFL---LDIF
SEYLEMVLQFGFVTIFVSAFPLAPLCALVNNLFESRCDAKKILMHYRRPVAVRVKSIGVWLTILNFVSKFAVFSNALIIAFTSEFIPHLVYRFSVSP--S
LEGYTNHSLSYMNTTELDWIG---------FD-DVCRYKDYRYPPEH-NKYAHTTMYWTVLASRLIFMVLFENIVVFLVLLISWAIPDIPGKLKDKIRRE
AHIVNHIMLEEARKSKRDCGKPD-------------------------------------
>tr|A0A087UTC1|A0A087UTC1_9ARAC Anoctamin (Fragment) OS=Stegodyphus mimosarum GN=X975_22901 PE=3 SV=1
----------------------------------------IDSASMMSVESAVFFDDKRRRIDFVLVYSTDPT-E-------------------------
---------------------AEHARCRSIFEENLVEEGLELEHVY--EETGLVYVKIHCPWEVLSRYGEILKFKMPMKSLDF---------SKY-YFRN
LFSLMNPDAC-GV---NYRFSTVYTRDKEY-FDVRKKEDFFSPAQRSRI-QFILKRKSFTNDH----IKKLLADGIYTAAYPLHE------S-PTNPRYF
LLKHWASYSCLFKTQPLDEIKHYFGVKIGLYFAWLGFYTYMLIPASIVGILCFIYGCLTLNSNVPSNEVCNSN--LVMCPKC-NECRYWYLNESCNAVRA
TYLVDNAATVFFAIFMSLWG-VFLEMWKRYSADITHRWDLTGFDTYE----EHPRPEYLARLANERKK---LNYEPF-----WRKRLPYTLMSTSVVLLL
VTVAVA-VVG-ILYRISVNAALLLSQD--LS--AAIITSTTAALLNLICIMIFNQFYTYAATCLTELELHRTQTEFDDSLTLK---LQFVNYYSSIFYIA
FFKG--LGHPGGYNL-----RQEECGTGGCLMELAIQLAIIMVGKQAL-NNMMEIMLPWLT-WLYQWWQIKKRR-NSGGTSHVSTRWEEDYALAEWTHLF
FEYLEMILQFGFVTIFVAAFPLAPLFALLNNILEIRLDARKLVCSYRRPVGVRVQNIGIWFRIMDSIGKLAVLTNGVIIAFTSDMIPRIVYRLTVSE-FT
LNGFVNHSLSYFNTSDFLNQSHHVVLPNSKEEVAVCRYRDYRNPPFSENKYAYSEEYWHLLSVRFAFVLVFENVILMTTTLTRWLIPDIPKKLMERIRHE
NFITNEIMIAQELRRAKGLASSP-------------------------------------
>tr|A0A090XD13|A0A090XD13_IXORI Anoctamin (Fragment) OS=Ixodes ricinus PE=2 SV=1
----------------------------------------EEGPPPVEEPGCVYLEGSRRKVDFILVYSPA-----------------------------
----------------------KNQAVRDIFEEELLKAGLLLEYVP--NQSGLCYVKIHAPWDVLSCFAEIMRLKMPVKWSLD-----------------
---CDTVEVARKG---HKQFAVTFAMSKEY-FDIPCKEDFFTSAQRAQI-HFILQRKSFSRKR----VSRLLADGVYLAAFPLHE-------GEGSPRAR
LRKQWASLLALFRGQPLDQIRRYFGVKVGLYFAWLGFYTYMLIPASVVGLACFLYGVFTLSSHVPVREMCADRGSLLMCPLC-NGCEYWRLQDSCTQAKL
SYLFDNGATVFFVVFMSVWG-AFLELWKRYSARITYQWDLSGFDTLE----ENARPEYLARLSKIKKR---IESSPF-----WKVKLPYSMLSCSVILLL
VLLAVA-VVG-IVYRMSVRATLALSNDE-MS--IPLITSTTAALLNLLCILLFNMVYTRLAVYLTDMEMPRTQTEYDDSLTLK---LQFVNCYSSIFYIA
FFKG--VGRPGKYNL-----QQEECGAGGCFLELSIQLAIIMVGKQAF-GALSELALPYAMRLWSH---L--SL-TPKDARLPKEPWERDYTLPDMTGLF
QEYLEMILQYGFVTVFVAAFPLAPLFALLNNTLEIRLDALKLLGSYRRPVGVRVRDIGIWYRIMDSLGKLAVLTNAVIIAFTSDLVPRMYYRWKVSP-GS
LEGFVDFSLSYFDVRDYGENVRHG---NTSLGARYCRYSDHRTPPWVENQYKRTAQYWEILVWKFAFVVIFENLIATLMTLIRWVIPDVPKSIREKIRED
NKLTNEIIILQELRRRHAIDPVP-------------------------------------
>tr|T1K2V6|T1K2V6_TETUR Anoctamin OS=Tetranychus urticae PE=3 SV=1
----------------------------------------ENDFDRHPDPDSHFFDDGERRIDFVIVNKSAQLFR-------------------------
---------------------ERFDKYRDLFEKNLIKEGLQLESCSGHGNSLLRFTKIHAPWGVLSRYAELLHFKMPVKVE-------------------
-EQ------------RGEKFTATYRLDKEYMFDIDKKENFFSQAQRSRI-DHILKRVSYGDS-----IDKLIEDGAYEAAYPLHE------H-SDRTRMQ
LYTNWASLWRLLDQQPLDDICNYMGAKFAMYFAWLGFYTTLLIPASIAGVVCFIYSIATY-YDPVSNSICTKLDDVAMCPLCSHDCDYWLLSSSCIDTFF
SYLFDNPSTIFFAIFMSVWS-FFTQFWKRYSVSITYQWDISSLDYYD----EIPRPEYLNKLDKNGK----LNYESF-----WKKRLPYMILSGSLVLFF
LSILIG-VFG-IFYRVSVKTALSEDLDPKIG--SSLISASSASFINVIFIIIFNWVHTKVAYKLTEMELPRTQTEFDNSLTLK---LEFVNYYSSLFYIA
FIKG--VRHPGDLY------NKEQCGLGGCFVELTIQLAFIMIGKQAI-FALLEMLQPWFEKKKLEKIINFN-----PKDILLLPQWEADYPLNNWTALF
YEYLEMIIQFGMVTIFVVAFPLAPLFALINNAFEIRLDARKFLSHYKRPVAVRIKDIGVWFHIINALGKLSILTSALTIAFTSSLVPKTYYYL---K--S
LDGFISWSISYYETKNLPQNLTD-------SLSTTCAYSGLRHPPGG-EQYKPTEEFWEILAYRLIFVVIYHNTILLFDTLLDWIIADVPKKLYRRIRQN
TYLTNEFIIAQEAIKTENDNKKS-------------------------------------
>tr|T1JP88|T1JP88_STRMM Anoctamin OS=Strigamia maritima PE=3 SV=1
----------------------------------------ITPIRVMTNSSALYFRDGMRKIDFMLAHSVDSE-P-------------------------
---------------------STGNEIRKTFESSLLEDGLQLEYEY--DDKRVQFIKIHASWEVLTRYAEIMKFKMPMKSKFQ---------SEVAIKDT
YLGCFKYDDT-LF---DKRFTCHFSREKEY-FDIINRDAFFSTAQRGLI-YFILRRSSFSLDK----IHKLMAEGVYTAYYPLHE------KDAPTPRGL
LYSEWASLRKIFKQQPLDHIKHYLGVKCGLYFAWLGFYTYMLIPASIVGFFCFVYGLVTMNDFIPSKEVCEFGQNITMCPVC-LLCDYWKLNQTCIHTKI
TYLFDNPATLVFAVFMSFWS-LFLELWKRYSANITHRWDLTGFDPNS----QQPRPEYLAKLAKLKKTK----DEPF-----WRWQVPTTIISWSIVLLM
ATIAVA-VLG-IFYRMSVMTALALYYDESNN--APLITSVTAAMINLICIMILNQVYRRIAVHLTELELPRTQIEYDDSLTLK---LQFINYYASIFYIA
FIKG--IGRPGAYNR-----RQEECGPGGCLMELSIQLSIIMIGKQVL-NTIMEMSLPVILRAYKS-IKSKTTI-KRSTSASTKTSWERDYPLLAWQELF
GEYLEMVLQFGFVTIFVAAFPLAPLFALLNNLFEMRLDAKKILTYYQRPIGRRVKNIGIWYRILDGIGKLAVITNAFIIAFTSNFIPRMVYLNFMND-GT
LQGYVNYSLSYFNTSDFTLDERPR----DPNGIEVCRYEDYRKHFSARHQYSYTHYFWHVLAARFAFVVVFENVIVFVVTLLRWLIPDESRQLREAIRQE
NYVINELIVQQEFVRARVELFRT-------------------------------------
>tr|Q4SSV5|Q4SSV5_TETNG Anoctamin (Fragment) OS=Tetraodon nigroviridis GN=GSTENG00013246001 PE=3 SV=1
----------------------------------------------------LCFSDGRRKVDYVLVFHQRRHSSIRSPASVS-----------------
-ASHEML-------SVVS--NHEMRMIREEFEANLLEAGLEIERDSERKTHGPSYTRLHAPWPVLCREAEFLKIKVPTKTSYKLKEESGFGSRMSTVWRK
LNQPFQPKVPHQDQESTKFLSHCFSRDKLHLYNITSKDTFFDNATRGRIVYEILRRTVCVRTCQTI-ISTLIAKGVYDSAFPLHDGDFAVVVEEKNDRQV
LHEEWARYSAFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQLLIPASIVGIIVFGYGMATMNTNIPSQEMCDDSLNFTMCPLCDGACDYWHLSTACGTARA
SHLFDNPGTVFFAIFMSLWAVLFLEQWKRRQISLSFSWDLTGIEEDE----EHPRPKYETILLQKRQRKQTTEGAAAVEKHDLEMDWLDTCINVSSILFM
FGLTFSAVFGVIIYRITVSALMAMSPDPEIKSNVRVTVTATAVIINLVVILILDEIYGSVALWLTELEIPKTETNFEERLILKAFLLKFMNAYAPIFYVA
FFKGRFAGRPGNYVYVFNDYRMEECAPGGCLIELCIQLSIIMLGKQLIQNNIFEIGIPKLKKLLRELKNKNPA-ARE-E-ERPPQQWRTWTT--PWLLLR
VSPLNSWARFGFVSLFVASFPLAPLFALLNNVIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILSGMGKFSVIINAFVISFTSDFIPRLVYQYVFSQTGT
MHGFIDHTLSHFNVSNFKPGTAPQTSEL--GNITVCRYKDYREPPWSPEAYAFSKHYWCVLAARLAFVILFQNLVMFLSLLVAWVIPDVPKTIVEQLKRE
KKLLVDVFLQEEKEKFQLIQTLF-------------------------------------
>tr|W5KEV4|W5KEV4_ASTMX Anoctamin OS=Astyanax mexicanus PE=3 SV=1
----------------------------------------QELGTLEQNEDSVYFRDGKRRIDFVLSYVDDKDGD--KKA--------------------
-------------------------ERRRLFEANLEKTGLHLELEDKLDDRKTYYLKIHAPWEVLGTFADVLKIKVPFKSD-------------------
---PFRLPPDIM---EPDYFTAPFDKR----FLIKDQETFFPPSTRNRI-YYILTHCPYYKED----IKRLLSNSTYTSAYPLHD----KATLCESERYH
LYKHWARFLCFYKEQPLNLIRKYYGEKIGIYFAWLGFYTEMLFFAAVVGVICFVYGLLSYD---N-KEVCDPDGKIVMCPLCDKMCSFWKLNLTCLSSRT
IHLFDNAGTVFFAVFMGIWV-LFLEFWKRRQARLKYEWDLVDFNEEE-------RPEFELKC---------KNEEPIK-------KCPRL-VSGATVLFW
TCLVVA-IIG-IAYRLAVYATFAGRK---IQ--PQQTTAVTASLINFAIILILNFLYGHVAIWITDM--PKTHSEYENSLTTK---FQFVNYYSSCFYVA
FFKG--VGYPGEYTYMFG---NEECAPEGCLIELTTQLGIIMSGKQLV-ANIQEIVLPLLKNWWTNRK-------RVQS--G-SSQWEQDHALKSLFGLF
DEYLEMVIQFGFITLFVASFPLAPLLALFNNILEVRLDAWKFTTQLQRPVAIRARNIGAWNEILNVVAVLSVITNAFIMAFTSEMIPRLVYLYAYHP-AT
MAGYISNSLSVYEISDLRAKNLSHFDANPTNI-TKCRYRDYRYPPGHPQEYKHTMQFWHILAARLAFIIIMEHIVFVVKFLVAYLIPDVPSDVRDRIRFE
QCLVQNRLVNEELKMIKSS-----------------------------------------
>tr|G1S833|G1S833_NOMLE Anoctamin (Fragment) OS=Nomascus leucogenys GN=ANO3 PE=3 SV=1
----------------------------------------SKNDMNYIASSGPLFKDGKKRIDYILVYRKTNIQ--------------------------
------------------------YDKRNTFEKNLRAEGLMLEKE---ASPDIMFIKIHIPWDTLCKYAERLNIRMPFRKK--------SMGR-----MQ
--TPMVLDKSAFP--ESDCYTGPFSRA----FIINNKDTFFSNATRSRI-YHMLERTKYENG-----IRKLINNGSYIAAFPPHE----SQHGPQNNRHL
LYERWARWGMWYKHQPLDLI-LYFGEKIGLYFAWLGWYTGMLIPAAIVGLCVFFYGLFTMN---SSQEICKA-TEVFMCPLCDKNCSLQRLNDSCIYAKV
TYLFDNGGTVFFAIFMAIWG----HYFLSLFSEAVHTWFLLHREIAR-------AKMQELV-----SF---NLRHPCP-------KVTRL-VSVSGIFFM
ISLVIT-VFG-VVYRLVVMEQFASFWNFI-Q--QF-ATSAAAVCINFIIIMLLN-AYEKIAYLLTNL--PRTESEWENSFALK---FQFVNLNSSIFYIA
FFLG--VGHPGKYNKLFD--RLEECHPSGCLIDLCLQMGVIMFLKQIW-NNFMEG-YPLIQNWWSRHKIKRGM-------DASIPQWENDWNLQPMHGLM
D--LEM-LQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGP-NC
LKGYVNNSLSFFDLSELGMGKSG-Y----------CRYRDYRGPPWSSKPYEFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRRE
KYLVQEMMYEAELEHLQQQRR---------------------------------------
>tr|H3AL09|H3AL09_LATCH Anoctamin OS=Latimeria chalumnae GN=ANO1 PE=3 SV=1
----------------------------------------LAPDQDAVSKNGIYFRDGKKKVDYVLAYHYKKSGSLRKHAGRI-----------------
-QQN-------------E--SDDKRLRRAEYEGKLMETGLELERDEETKTHGVGFVKIHAPWNVLCREAEFMKLKMPTKKVFESKETHGIMQKIHSLAYK
LTKPIRPKVKEHKENLVKHLSYPFSREKQHLFDLSDKDSFFDSKTRSTIVYEILKRTTCTKAKYSM-ITSLLANAVYSAAYPLHDGDCEGENADPNDRKL
LYEEWASYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQMLIPASIVGIIVFLYGCATVDEDIPSMEMCDQRENISMCPLCDKTCSYWKLSSACSTARA
SHLFDNPATVFFSIFMALWAAMFMEHWKRRQMRLNYRWDLTGFEEEE----DHPRAEYEAKVLQKTQRKEH----TEKEKLTWKDRFLAYLTNFVGIIFM
IGLTFAIVFGVIIYRISTATAIAVSSSPSAKSNVRVTVTATAVVINLVVILILDEVYGSIARWLTQIEVPRTDKSFEERLIFKAFLLKFVNAYTPIFYVA
FFKGRFVGCPGSYVYLFQSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKSKRQSSVQLEEHAKKKKRYETDYNLEPFSGLT
PEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVAELRRPVAVRAKDIGIWYNILRAVGKLAVIINAFVISFTSDFIPRLVYLYMYSRDGT
MHGFINHTLSYFNVSHFQPGTEPTDPLELGYAVQICRYKDYREPPWSENKYDISKEFWAVLAARLAFVIIFQNLVMFMSDFVDWIIPDIPKDISEQIHKE
KVLMVELFIKEEQGKLQLLESFS-------------------------------------
>tr|A0A0B2VX62|A0A0B2VX62_TOXCA Anoctamin OS=Toxocara canis GN=ANO5 PE=3 SV=1
----------------------------------------SSKSEGE-TRRYAYFSDGWRRVDYVLAYEA--NENADSEDEP------------------
---------------------SNKAKRRRIYESNLKMRGLELEHVKGE-CSNIRFVLVHVPFDLLCKQAEKLGIEMRVRSDNCL----------------
---TFPEEIQAFI--EPRNQYYPFTCDD---FSGGDAENLFSSADRIFI-HDILCRTRYGRGD----IENMLKREIYTAAYPLHEE---EEMKKFSTRQF
LYWLWAKLRYFYKFQPLFLIKEYFGSKIAIYFVLVGYYTKFLIPCALLGVICFLFGLFTIS-DLPSSEICRKENDVIMCPSC-KWCDYTRLNSSCFFSKL
SYIFDNISTVVFAILMSVGA-LFIEGWKRYNADVAWRLGLLDTGSHE----EGIRLAYLLQSLRSSN----DPEPPL------SKRLPTILASGVTVVFF
LCLILG-VIG-IVYRIVLMQVLY--RVNSMR--AAIFTSVTTAILNLIVILAMSYVYSFLALKLTDWEYPRTQSEFEKSYTVK---FQFINYYSSIFYVA
FFKG--SGLPGR--------RPEDCDPAGCMVELVILLTTIMFGKTAY-NAAMEFFNPVILTLFRGCTLKIP--REMDSAIVRVPRWEWDYALTPTQFLF
DEYLDIVIQFGFVTLFVSAFPLAPLFALINNLLEARLDAYKFVVATRRPLPERAKDPGVWLSIMDLISKAAVLTNAFVIAFTSDFIPRMVYL--YG-HPS
LEGYVNSTLSLFESSSLHTP----------HNVTACWFRDFRKPPCTLDKYGVTSLWWVILSFRLGFVIVFAHAVLAVKAFIAYVIPDMPTRVFIQLQRQ
RSLSFAELSEGTRRSM--------------------------------------------
>tr|A0A0M3JR94|A0A0M3JR94_ANISI Anoctamin OS=Anisakis simplex PE=3 SV=1
----------------------------------------GTPQSEE-TTRYVYFSDGRRQVDYVLAYEADSSLISNQEEES------------------
---------------------SKKSKRRRMYEENLKIKGLELEYVKGE-CSNMSFVLVHVPYDLLSKRAEKLGIEMRVRADGPL----------------
---GFSNEINALI--EPRNQYHPFTSDDVECFCGEDAENFFSSADRILI-NDILSRTKFGRGD----IQNMLKSEIYSAAYPLHEE---PIMRDFSTRQF
LYWLWAKLRYFYKFQPLFLIKEYFGSKITIYFVLVGYYTKYLVPCALIGLLCFFYGLLTIS-DVPSNQICERSNDIVMCPSC-KWCDYKRLNSSCFYSKL
SYIFDNISTVLFAILMSVGA-LFVEGWKRYNADVAWRLGLLDTGSHE----IRIRLAYLLQSLRSSD----DPEPPL------RKRLPTILASGVTVIFF
LCLILS-VIG-IVYRIVLMQMLY--RVDMMR--AAVFTSVTTAILNLIVILIMSYFYSFLALKLTDWEYPRTQSEFEKSYTVK---FQFINYYSSIFYVA
FFKR--SGLPGR--------RPEDCDPAGCMVELVILLATIMFGKTAY-NAFMEFFNPVILTLFRGFTLKIP--REMNSAAFRAPRWELDFALTPTQFLF
DEYLDIVVQFGFVTLFVTAFPLAPLFALINNVLEARLDAYKFVVATRRPIPERAKDPGIWLSIIDTLSKAAVLTNAFVIAFTSDFIPRMVYL--YT-NPN
LDGYVNSTLSIFESSSLHAP----------HNVTTCWFRGYRKPPCTLDKYGVTHMWWIVLSFRLGFVVVFAHVVLAVKALIAYLIPDMPTRVFIQLHRQ
RSGSLGGLSEGTERTV--------------------------------------------
>tr|A0A0N5CME9|A0A0N5CME9_THECL Anoctamin OS=Thelazia callipaeda PE=3 SV=1
----------------------------------------SGSRPKH--YETMYFKDGKRKIDYILTYDYDEMDGEDDSS--------------------
---------------------EKRASKRLQYEINLRQLGLELEHVDGK-CKKTRFVLVHAPFSLLLKQAESLSLKMPVLSDGIL----------------
---TYDEKTNVRL--ETNYFTAPFIASHIKCYVGEDPDTFFDDSERSRL-YDLLIRTRYDTDE----IQRLIKNGTYTSAFPLHE------AEKCTDREL
LYWNWARITNIYKFQPLSLVKKYFGSKVGWYFAWLGYYTKVLMFVSVIGIMCFSYGVSTVS-DIPSNDICGSDAKAILCPTC-KYCDYTRLNSSCIYSKL
SYVFDNTSTVVFAALMSIFA-LFLEGWKRYHAEVAWKWGLLDFEVDE----ETIRPEYQLRVKKAKT----FNQETF------RDKFLRFVGSGVTVLFF
LFLVLA-VIG-IIYRIVFSQVLY--RIDRMK--ANLVTFTTAATLNLAVILAMSYLYTYLALKLTDWECPRTQRDFDNSYTFK---FQFINYYSSIFYIA
FVKG--SSVPGR--------RPEECDPAGCMVELVIQLAIIMCGKQFW-NGFVEFAWPLLMTWLRSL--QLL--TEEMGRYGMIARWEHDYILNPVQFLF
DEYLEMVIQFGFVTLFVSAFPLAPLFALLNNILEIRVDAYKYVVATRRPMPERERDIGIWLPILNMISRAAVL--ACIIAFTSDFIPRFVYRFVYM-HDD
LYGFVNSSLSFYDSSKIF-V----------ENITVCRFRDYRKVPCTIDEYGLTMRWWIVFSFRLAFILIFEHTVALVKAAVAYVIPDIPANIFIQLQRQ
RFLARQARISDITSTANIHNDFK-------------------------------------
>tr|A0A044R030|A0A044R030_ONCVO Anoctamin OS=Onchocerca volvulus GN=WBGene00247693 PE=3 SV=1
----------------------------------------SKLQRND--FQTTYFKDGKRKIDYVLTYECNDIDDEKESS--------------------
---------------------ERKVIKRLQYEANLRQLGLELEHVEGK-CKRTHFVLVHAPFLLLMKQAESVCLKMPVLSDGIL----------------
---TFDEKTNERL--EPNYFTAPFIAAHLECYVGENPDTFFDDSERSRL-YDLLIRTKYDTHD----IERLIKNGTYTSAFPLHE------ADRSTDREF
LYWNWARITNICKYQPLSLIKKYFGSKVGWYFAWLGYYTKTLIPASVIGILCFIYGILTIS-DIPSNDICGSDAEVILCPTC-RYCDYTRLNSSCIYSKL
SYVFDNTSTVIFAAMMSVFA-LFLEGWMRYHAEVAWKWGLLDFEVDE----ETIRPEYQLRVKKSKT----INLETF------THRFLHLIGSGITVLFF
LFLVIA-VIG-IIYRIVFSQVLY--RVDKMK--ANLLTFTTAATLNLIVILAMSYFYSYLALKLTDWECPRTQLEFDNSYTFK---FQFINYYSSIFYIA
FVKG--SSVPGR--------RPEECDPAGCMVELVIQLAIIMCGKQFW-NGFVEFAWPVLMTWLRSL--RVL--IEKLSGRGRIARWEQDYILNPVQFLF
DEYLEMVIQFGFVTLFVSAFPLAPFFALLNNIFEIRVDAYKYVVASRRPVPERARDIGIWLPILSLISRAAVLVNACIIAFTSDFIPRFVYRFVYM-HDE
LYGYVNNSLSFYDSSGIF-V----------ENITICRFRDYRKSPCAIDDYGFTTQWWIVFAFRLAFILIFE--MAMVKAMIAYVIPNIPANIFIQLQRQ
RFLARQARISDITSAVSARNGLE-------------------------------------
>tr|A0A0P7WBS1|A0A0P7WBS1_9TELE Anoctamin-6-like OS=Scleropages formosus GN=Z043_121582 PE=4 SV=1
----------------------------------------SPQTEFNNQPDSLFFNDGQRRIDFVLVYEDEDKKEF--EK--------------------
---------------------QRRKRRREFFEADLMVRGLELEASRSVLDDKVVFVKVHMPWDVLCTYAEVLHIKLPIQND-------------------
---LCEPSKDVI---EVDYFTAPFEKD----FCVKDRAQFFAPDMRSRM-YYVLSRAYYEVR-----INKLLDGGVYKAAFPLHD----KSVQCANERYR
LYQEWAHPKNFYKTQPLDLIRKYYGEKIGIYFAWLGFYTYMLAGAAIVGLGCFIYGYQTQH---S-KEVCDPLGRIVMCPQCDKECTYWMLNSTCDSSKK
LCIFDNFGTLVFAVFMSIWV-LFLEFWKRYQAELEYEWDTVQFL--E-------RPEYEAKC---------INEKPYT---SC--KCLRV-CGAGTVLFW
VALIIA-IVG-IVYRLAAFFTFSSNRKELLQ--PQMATSVTASVISFVVIMVLNILYERVAIWITDF--PRTRTEYENSLTLK---FQFVNYYSSCFYIA
FFKG--VGFPGKPVYWLGTY-NEECDPGGCLIELTTQLTVIMGGKAIW-NNIQEVLFPWVKNLISRC-------CRVRSEKV-IPRWEQDFQLQAYLGLF
YEYLEMVIQFGFVTLFVASFPLAPLLAFLNNVVEIRVDAWKITTQFRRMVPEKAQDIGAWQPILQAVAILAVATNAMITAFTSDMIPRLVYYFPYGD-HT
MEGYINGSLSVFDIHNFSTESE--PLTKPY-------YRDFRYPPGHPWEYQHNIYYWHVIAAKLAFIIVLEHVVYLTKFILCYMIPDVPLAVKEKIKRE
KYLTQVILHEANLKLVSKHLKPI-------------------------------------
>tr|W5NI34|W5NI34_LEPOC Anoctamin OS=Lepisosteus oculatus PE=3 SV=1
----------------------------------------AEFVEFNNKPDSLFFNDGTRRIDFVLVYEDEDKKEY--DK--------------------
---------------------QRRKRRREYFEASLMKMGLELEATH--LDEKVIFVKVHAPWEVLCTYAEVLHIKLPIQND-------------------
---YFYPSKELI---ETEYFTAPFEKD----FCIKDQDTFFTPSMRSRI-YYILSRALYEVR-----ITKLLGSVVYKAAYPLHD----KSKNCPNERYL
LYNEWAHPKSFYKMQPLDLIRKYYGEKVGIYFAWLGFYTKMLAFAAVVGLGCFIYGYQTKE---S-QEVCDPQGNIVMCPQCDRECAYWRLNSTCESSKK
LCIFDNFGTLVFAIFMAVWV-LFLEFWKRYQAELEYEWDTTEFL--E-------RPEYEAKC---------LNVKPYT---TC--KCMRV-CGIGTVFFW
ILLIIA-VVG-IVYRLAVFFSFSANRR--LE--PQMATSVTASIISFIIIMILNIVYERVAILITDF--PRTKTEYENSLTMK---FQFVNYYSSCFYIA
FFKG--VGHPGDPVYWLGKY-NEECDPGGCLLELTTQLTIIMGGKAIW-NNVQEVLIPWLKNLISRY-------CSVGSEKV-IPRWEQDYQLQPMLGLF
YEYLEMVIQFGFVTLFVASFPLAPLLALLNNIFEIRVDAWKITTQFQRGVPEKTQDIGAWQPILQGIAILAVATNAMIIAFTSDMIPRLVYYYPYGD-YT
MRGYINSTLSIFRIDDFSNASKPLPEKNPY-------YRDLRYPPGHPRQYEHSIYYWHVIAAKLAFIVVVEHVVYFTKFILSYGIPDVPLEVKEQIKRE
KYLTQKLLHEANLKLVTKRLKPV-------------------------------------
>tr|A0A087Y4Z4|A0A087Y4Z4_POEFO Anoctamin OS=Poecilia formosa PE=3 SV=2
----------------------------------------P-----QASSEGLYFCDGLRKVDYVLVFHHRRHGSLRCTGTAS-----------------
-VSQDQL-------SIVS--NHEMHLIRQEFEANLLEAGLEVERD---KTHGPSFTRIHAPWPVLCREAEFLKIKVPTKQSYELREESGFGSSMSSVWRK
LNQPFEPKVPHQDHGSTKFLSHCFSRDKLHMYNITSKDTFFDNATRGRIVYEILRRTVCVRTCQTI-ISTLIAKGVYDAAFPLHDGDFKVTLEERNDRQV
LFEEWARYSAFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQLLIPASIVGIIVFGYGVATVDTNIPSLEMCDERLNFTMCPLCDGACDYWHLSTACGTARA
SHLFDNPATVFFAIFMSLWAVLFLEHWKRRQISLSFSWDLTGIEEDEAKSDEHPRPKYETILLEKRQRKQGSMPYTVAEKLTWKDRLPGYFMNISSILFM
FGLTFSAVFGVIIYRITISALMAMSPDPETKSNVRVTVTATAVIINLVVILILDEIYGTVALWLTELEIPKTETNFEERLILKAFLLKFMNAYAPIFYVA
FFKG-FAGRPGSYVYVFNDYRMEECAPGGCLIELCVQLSIIMLGKQLIQNNIFEIGIPKLKKLIRTLKEKEPT-KKD-E-ERPPRQWNLDYALVPFEGLT
PEYMEMIIQFGFVSLFVASFPLAPLFALLNNVIEIRLDARKFVTELRRPVAARAKDIGIWYNILSGMGKLSVIINAFVIAFTSDFIPRLVYQYMYSQTGT
MHGFIDHTLSFFNVSNFKPGTAPHSDKF--PQLFV-FYKDYREPPWSSDAYQFSKQYWSVLSARLAFVILFQNLVMFLSLMVAWVIPDVPKTIVEQLKRE
KKLLVDLFLQEEKEKFQL------------------------------------------
>tr|H0ZNY1|H0ZNY1_TAEGU Anoctamin (Fragment) OS=Taeniopygia guttata GN=ANO2 PE=3 SV=1
----------------------------------------------------LHFRDSKRKVDYVLAYHYRRRLAQHVPGAAS-----------------
-PE-ASV-------ALVS--NEERRLQREEYERNLLEAGLEIEKDPE-KSQGLSFVRIHAPWQVLSREAELLKIKMPTKK-YEITEEKGILKTLNEIWCK
LTEPLQPQVPQQ-EDKMKTLSYPFSREKIYLYNIKDRDTFFDNATRSRIVREILKRTS-TKARNSM-IGTLIANNVYDAAYPLHDGEYEG-NDDMNERKL
LYQEWARYGAFYKFQPIDLIRKYFGEKIGLYFAWLGLYTEFLIPSSVVGIIVFLYGCITIESDIPSKEMCDQRNAFTMCPLCDKFCDYWNLSSACATARA
SHLFDNPATVFFSIFMALWA-MFLEQWKRLQMRLSYFWDLTGLEEEEVIQKEHPRPEYETKLLQKKLKKKNGNDAERRDKLTWTDRMPGYAANFGLILFM
ILLAFSAVFGVIVYRITTAAALSFSANETTRSNVRVTVTATAVVINLVVVLILDEIYGAV-KWLTEIEIPKTEKIFEERLILKAFLLKFVNSYASIFYVA
FFKG-FVGRPGRYVYVFEGYRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKLKKLFRKLKDERTE-KMDTNQSKDPQQWDLDYILEPFTGLT
PEYMEMIIQFGFVTLFVASFPLAPVFALLNNIIEVRLDAKKFVTELRRPDTVREKDIGIWYNILSGIGKLSVIINAFVIAVTSDFIPRLMYQYAYSQNGT
MHGFINHTLSYFNVSQLKAGTQPENSLFG-QEVSFCRFKDYREPPWSPHQYEFSKQYWAVLSARLAFVILFQNLVMFLSVLVDWMIPDIPKDISEQIKKE
KTMLVDFFLKEEHEKLKLIESFM-------------------------------------
>tr|A0A093QCG9|A0A093QCG9_9PASS Anoctamin OS=Manacus vitellinus GN=N305_07553 PE=3 SV=1
----------------------------------------------------MHFRDSKRKVDYVLAYHYRKRLARPPPGPGS-----------------
-PERARRSA---SLALVS--NEEKRLQREEFERNLVEAGLEIEKDPE-KSQGLSFVRIHAPWQVLSREAELLKIKMPTKK-YEITEEGGILKTLNEIWCK
LTEPLQPQVPQQ-ENKMKNLSYPFSREKIYLYNIKDKDTFFDNATRSRIVREILKRTS-TKARNSM-ISTLIANNVYDAAYPLHDGHYEG-NDDMNERKL
LYREWARYGAFYKFQPIQLISGKQLLHLGYSFAYLSCKTALDILISA-----ESAGCGRCALVIPSKEMCDQRNAFTMCPLCDKFCDYWNLSSACATARA
SHLFDNPATVFFSIFMALWA-MFLEQWKRLQMRLSYFWDLTGLEEEE----EHPRPEYETKLLQKKLKNKT----DEKEKLTCSDRMPGYAANFGLILFM
IMLTFSAVFGVIVYRITTAAALSFSTNETTRSNVRVTVTATAVIINLVVILILDEIYGAV-KWLTEIEIPKTEKTFEERLILKAFLLKFVNSYAPIFYVA
FFKG-FVGRPGRYVYVFKGYRMEEA--RGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKLKKLFRKLKDERTE-KVDTNQAKDPQQWDLDYTLEPFTGLT
PEYMEMIIQFGFVTLFVASFPLAPLFALLNNVIEVRLDAKKFVTELRRPDTVRAKDIGIWYDILSGIGKLSVIINAFVIAVTSDFIPRLMYQYAYSQNGT
MHGFINHTLSYFNVSHLKAGTEPENSLFA-QDVLFCRFKDYREPPWSPNQYEFSKQYWAVLSARLAFVILFQNLVMFLSFLVDWMIPDIPKDISQQIKKE
KSVLVDFFLKEEHEKLKLIESFM-------------------------------------
>tr|F7E7C8|F7E7C8_XENTR Anoctamin (Fragment) OS=Xenopus tropicalis GN=ano2 PE=3 SV=1
----------------------------------------Q-Q----TKPSGMHFGDGKRKVDYVLAYHYRYRSSHHNGSPKH-----------------
-NNSDH----------S----EEKKIQREEFEQNLMEAGLELEKDPE-KSQGLNFVRIHAPWPVLSREAEFLKIKVPTKK-YEVKQDTGILKKLYSLWNK
CTKILQPKVPQFSENKMKHLSYPFSRDKMHLYDIKDKDTFFDNATRSRIVHEILKRTSSVKAKYSM-ITTLIANNVYDSAYPLHDGDYDH-KNETNERML
LHREWARYGAFYKYQPVDLIRKYFGEKIGLYFAWLGLYTWLLIPASLVGIIVFLYGCATIDADIPSQEMCDQEQGFVMCPLCDKACDFWKLSSACGTARA
SHLFDNPATVFFSVFMALWA-LFLEYWKRLQMRLSYFWDLTGLEEEEHQSQEHPRPEYETKLLLMKEKSKG--RRNKKEKLTWRDRIPAYLVNFSAILFM
IALTFSAVFGVIIYRITTAAALAVSTSEVTRSNVRVTVTATAVIINLVVILILDEIYGSV-KWLTEIEVPKTEKTFEERLILKAFLLKFVNSYASIFYVA
FFKG-FTGRPGSYAYIFHGYRMEECAPGGCLIELCIQLSIIMLGKQLIQNNLFEIAIPKFKKLYRKFKDERAE-GNNLNNTKEPQQWVRDYALEPFTGLT
PEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEVRLDAKKFVTELRRPDAVRAKDIGIWYNILSGIGKFSVIINAFVISVTSDFIPRLVYQYMYSENGT
MHGFLNHTLSYFNVSHLKPGTQPENSQFA-QNVEICRYKDYREPPSSPNQYDFSKQYWTILAVRLAFVILFQNLVMFLSAVVDWLIPDIPKDISEQIKKE
KTMLVNVFLKEEHKKLQLLENFL-------------------------------------
>tr|U3I550|U3I550_ANAPL Anoctamin OS=Anas platyrhynchos GN=ANO2 PE=3 SV=1
----------------------------------------------------MHFRDSKRKVDYVLAYHYRKRLAQHQHGASS-----------------
-PEPMNRAG---SMTVVS--NEEKRLQREEYEHNLVAAGLEIEKDAE-KSQGLSFVRIHAPWQVLSREAELHKIKMPTKK-YEIKEEGGILKKLNKIWCK
LTEPLQPQVPQ--ENKMKSLSYPFSREKIYLYNIRDKDTFFDNATRSRIVHEILKRTS-TKARNSM-INTLIANNVYDAAYPLHDGEYEG-NDDMNERKL
LYQEWARYGVFYKFQPIDLIRKYFGEKIGLYFAWLGLYTEFLIPSSVVGIFVFLYGCITIESDIPSKEMCDQRNAFTMCPLCDKFCDYWNLSSACATARA
SHLFDNPATVFFSIFMALWEAMFLEQWKRLQMRLSYFWDLTGLEEEEEEKQEHPRPEYETKLLQKKMKNKNNEPPDEKDKLTWNDRIPGYAANCGLILFM
IMLTFSAVFGVIVYRITTAAALSFSTNETTRSNVRVTVTATAVIINLVVILILDEIYGAV-KWLTEIEVPKTEKAFEERLILKAFLLKFVNSYAPIFYVA
FFKG-FVGRPGHYVYVFDGYRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPYVSQPYPLPHFIPTA-IQG-LGRCPANEWM--NYSKYLARGH
PRISLPVIQFGFVTLFVASFPLAPLFALLNNIIEVRLDAKKFVTELRRPDTVRAKDIGIWYNILSGIGKLSVIINAFVIAVTSDFIPRLMYQYAYSQNGT
MHGFINHTLSYFNVSHLKAGTQPENSPFA-QDVLFCRFKDYREPPWSPNQYEFSKQYWAVLSARLAFVILFQNLVMFLSVLVDWMIPDIPKDISEQIKKE
KSVLVDFFLKEEHEKLKLIESFI-------------------------------------
>tr|H9H972|H9H972_MONDO Anoctamin OS=Monodelphis domestica GN=ANO1 PE=3 SV=2
----------------------------------------LAVDPDTHCKYGLYFRDGKRKVDYILVYNYKRTAAHKILARRV-----------------
-LHG-------------D--VDDRRFRREEYEGNLLEAGLELERDEDTKIHGLGFVKIHAPWNVLCREAEFLKLKMPTKKMYQINQSRGLINKINSVLQK
ITEPIQPRVGDHGSQTVKRLSFAFSREKQHLFDLTDKDSFFDSKTRSTIVYEILKRTTCAKAS---TITSLLANGVYSAAYPLHDGDFEGD-VEFNDRKL
LCEEWATYRAFYKYQPIDLVRKYFGEKVGLYFAWLGVYTQMLIPASIVGIIVFLYGCLTVDENIPSMEMCDQWNNITMCPLCDRTCSYWKLSSACATARA
SHFFDNPATVFFSVFMALWAAMFMEHWKRKQMRLNYIWDLTGFEEEEETVKAHPRAEYEAKVLEKSLRKDSLPVGMDKEKLTWKDRLPAYLTNLVSILFM
IGLTFAIVFGVIIYRISTAAALAISS----RSNVRVTVTATAVIINLVVIIILDELYGSIARWLTLIEVPKTDKNFEDRLIFKAFLLKFVNAYTPIFYVA
FFKGQGATTPHVVQDGF------QAGPGSVWRGRCVH---HHVGKQLIKNNLFEIGIPKMKKFFRYLKQRP---ADHEESTKKKQRYEVDYNLEPFAGLT
PEYMEMSEYAGKASALLQLVPVVPCSAGLPSPLTLSLDRESGRDSLLAPPRGCVSSSGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSSNGT
MHGFVNHTLSSFNVSDFQPGTAPNDPQDLGYEVQICRYKDYREPPWSENKYEISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWIIPDIPKDISQQIHKE
KVLLVDLFMKEEQGKQHMLETLK-------------------------------------
>tr|G1KIN6|G1KIN6_ANOCA Anoctamin (Fragment) OS=Anolis carolinensis GN=ANO2 PE=3 SV=1
----------------------------------------QVGATERTVPGMMHFRDSKRKVDYVLAYHYRKRISH--VGDGS-----------------
-PGLLHRPP---SLAIIS--NETKWEQRNQFESNLVEAGLEIEKDVE-KSQGLSFVRIHAPWNVLSREAEFLKIKMPTKKKNYNKKNRPD----IKIWFN
KILKLTYLLSNTQV-TFKKKSLMYASSSYLKYNISDKDTFFDNATRSRIVHDILKRTYSTKAKNSM-INTLIANNVYEAAYPLHDGEYE--NKEMNDRKL
LYQEWARYGVFYKFQPVDLIRKYFGEKIGMYFAWLGLYTEFLIPSSIVGIIVFLYGCVTIESDIPSKEMCDHHNTFIMCPLCDKICDYWNLSTACATAQA
SHLFDNPATVFFSIFMALWATMFLEQWKRLQMRLSYFWDLTGLEEEELQLQEYPRPEYETKLLRKNLKQKIEESEDEKEKLTWKDRTPGYLVNFASILFM
LYIIRTTNFGLVIYRIQNMMAYNEINKKNTKISLYIENIVTKIVLNFKSLMIDHQIYQLILSLLFMAEVPKTEKAFEERLILKAFLLKFVNSYAPIFYVA
FFKG-FVGRPGKYVYVFAGYRMEECAPGGCLMELCIQLSIIMLGKQLIQNNVFEIGVPKLKKLFRKLKDERSG-KSDLNLSKRPQQWELDYVLEPFTGLT
PEYMEMIIQFGFVTLFVASFPLAPVFALLNNVIEIRLDAKKFVSELRRPDTVRAKDIGIWFNVLSGIGKFSVIINAFVISVTSDFIPRLVYQYAYSFNGT
MHGFINHTLSYFNISDFKTGTQPENSQFH-QEVSFCRFKDYREPPWSENQYEFSKQYWSVLAARLAFVIIFQNLVMFLSILVDWMIPDIPKDISEQIKKE
KSVLVDFFLKEEHEKLKLIENFI-------------------------------------
>tr|K7FTC6|K7FTC6_PELSI Anoctamin OS=Pelodiscus sinensis GN=ANO1 PE=3 SV=1
----------------------------------------LCQDPDANCKYGLYFRDGKRKVDYILVYHYKKSSVSRTLARRI-----------------
-HHN-------------D--SDDKRFRREEYEGNLMEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFLKLKMPTKKVYQINQGHGLLKKINSVIQK
ITEPIQPKVAEHKPQTMKRLSYPFSREKQHLFDLSDKESFFDSKTRSTIVYEILKRTTCTKAKYSMGITSLLANGVYSAAYPLHDGDYEGENVELNDRKL
LCEEWASYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQMLIPASIVGVIVFLYGCATVNDNIPSKEMCDERNNITMCPLCDKTCSYWNMSSACATARA
SHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKAHPRAEYEAKVLEKSLRKEYLPAGTDKEKLTWKDRFPAYLTNFVGIIFM
IGLTFAIVFGVIIYRISTAAALAISSTNSGRSSVRVTVTATAVIINLVVIIILDEVYGCIARWLTQIEVPKTDKNFEERLIFKAFLLKFVNAYTPIFYVA
FFKGRFVGRPGDYVYIFHSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYIKLKRQRPLDHEEHMKKKQRYEVDYNLEPFAGLT
PEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRAVGKLAVIINAFVISFTSDFIPRLVYLYMYSENGT
MHGFVNHTLSYFNVTDFQEGTAPNDQMGPDHKVHICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWIIPDIPKDISQQIHKE
KVLMVEVFMKEEQGKLQMLETWK-------------------------------------
>tr|T1G0M9|T1G0M9_HELRO Anoctamin OS=Helobdella robusta GN=HELRODRAFT_71534 PE=3 SV=1
--------------------------------------------------SQLTFRNGNKRIDFVLIWETKPT-D-------------------------
---------------------ESKKEIRESFERNLVKEGLQLEWDI--EGRHLQCTMVHAPLELLTRYAGILKIRMPIEEAWD---------MMDDAVLK
VLQ-FQLDPL-RV---KKKFTYPYDSTKTY-LLNRKLYFLFSHATRSRI-DYVLRRKEYFKPL----IKRLLADSVYNAAYPLHE-------SRMSMRKL
LYDNWANWRSWYKVQPLNYIRTYFGEKIGLYFAWLGYYTYFLIFPSFVGFIVFVYGIFSMGDDVVSKESCDERNNFTMCPLC-KLCAYWSLDQICSSIRA
MHLFDNGATVFFAIFMSFWA-IYLEMWKREQAGIQFLWDLRNFEEEE----EPPRPEYFTRKAKSKYV---YNEEPF-----WRRQIPVHCASFSAVLFL
VAVAIA-VVA-VFYRISIITSIYMMND--LY--AAIVVSITAACINLVVIFILNFFYTKLAILLTEWECFRTQSEYDNSLTFK---LQFVNYYSSLFYIA
FIKG--GSQENYLTV-----QRQEECQGSCLTELCIQLAIIFVGKQLIQNTLIEIYLPYVFVWLK--KKLCTSR-EERQLMKHYKPWEKDYALEDVMGLF
NEYLEMMIQFGFVTLFVAAFPLAPFFALINNIIELRSDANKFVTQLRRDVPIRTATIGIWYDILYGLSKFSILTNALIIAFTSSFIQRQLYTHVYST-GS
LDGFVNNSLSFFNVSDMPENVAPLEVLIKPNGTVFCRYQDYREPPWSSRKYKYSAQHWNMVAAQFIFVLIFENLIVLLVGLIAYIIPDVPYKLHQQMRQE
TILTHELVLETELKRAKGSGGEV-------------------------------------
>tr|A0A060VYH2|A0A060VYH2_ONCMY Anoctamin OS=Oncorhynchus mykiss GN=GSONMT00080783001 PE=3 SV=1
----------------------------------------KSDEAASGPKQGPTFQDGQRRVDYVLTYHVQKPQSVRRK--T------------------
-SR-F-----------AD--YDDKRFRQTEFEDNLREVGLELEKDEG-KIPGIGFLKIHAPWNVLCREAEFMKLKMPTKKVYEVKQGSNVVERINLFIHK
VTAPLHPKVEPNRPQNVKHLSHPFSREKQHLFDLSDRASFFDSKTRASIVYEVLKRTRCTKAKYTM-ITSLLGNGVYTAAYPLHDGDVDGM-AEANDRKI
LYEEWASYSVFYKYQPIGLIRKYFGEKIGLYFAWLGVYTQMLIPAAIVGVIVFLYGCATVDNDIPSMEICDPRNNITMCPLCDRACSYWKLKTACGTARA
SHLFDNPATVFFSIFMALWATMFMEHWKRRQMRLNYIWDLTGFEEEE----DHHRAEYEIQVMQKTLKKQD----DTKVKLTCTDRAPAYMMGLFIMLFM
IGVTFAVVFGVILYRISIRAALHMSSNPTARSNIRATVKGTAAVINLVIIIIMDEVYGAVARWLTLLEVPKTDKSFEERLIIKTFVLKFANAFSPIVYLA
FFRG-MVGRPGDYVYVIGSYRMEECAHAGCLMELCIQLCITMLGKQLIQNNLFEIGIPKIKKLIRRRKSDMDSQ-QQEDYNMTLQRHEKDHFLGPFVGLS
PEYMEMIIQFGMVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTEVRRPIAARAKDIGIWYNLLRGLSKVAVIVNAFVISFTSDFIPRLVYQYMYSPDGS
MHGFVNHTLSYFNVSDFQPGTAPLQPMHLGYEVQICRYKDYRETLWSNTPYDLSKEFWAILACRLAFVIVFQNVVMLMSDFVDWLIPDIPKDISLQIHKE
KILMVELFMKEEEGKKLLRDNH--------------------------------------
>tr|G3PN04|G3PN04_GASAC Anoctamin (Fragment) OS=Gasterosteus aculeatus PE=3 SV=1
-------------------------------------------------RLGPYFTDGRRRVDYVLAYHIQKPSSIRRQ--P------------------
-SR-F-----------GD--NNDKRFRRDEFEENLLETGLQLEKDEG-KIPGIGFLKVHAPWNVLCREAEFMKLKMPTKKVYEVKQGSNVVEKIRLFIHK
VTAPLHPKVDANRPQSVKPLSHPFSREKQHLFDLSDRDKFFDSKTRNSIVYEVLKRTKCTRAKYSM-ITSLLANGVYTSAYPLHDGDIEGV-AEANDRKL
LYEEWASYSVFYKYQPIGLIRKYFGEKVGLYFAWLGVYTQMLIPAAIVGVIVFLYGCATVDGNIPSMEICDPRNNITMCPLCDRACSYWKLVTACGTARA
SHLFDNPATVFFSIFMALWAVLFMEHWKRRQMRLNYIWDLTGFGEEEEEHKDHNRAEYEFRVMKKTMRQDN-RMEGEKVKLTCTDRMPAYLTTVVMMGFM
ILVTFAIVFGVILYRISIKAALHMSTSTVARSNIRATVKTTA----------VDEIYGAIARWLTTLEVPKTDKNYEERLIFKTFVLKFVNAFTPIVYLA
FFRG-LVGRPGSYLYVVGSYRMEECAHAGCLMELCIQLCITMLGKQLIQNNLFEIGIPKLKKLLRRRKSDLEE-----EVNKTLQRHEKDHMLGPFTGLS
PEYMEMIIQFGMVTLFVASFPLAPLFALLNNIIEIRLDAKKFVMELRRPIAAKAKDIGIWYNLLRGLSKVAVIVNAFVISFTSDFIPRLVYQYMYSVDGT
MHGFVNHTLSYFNVSDFQPGTDPIQPMHLGYKVEICRYKDYREPPSSSTPYELSKEFWAVLAARLAFVVVFQNVVMLMSDFVDWLIPDIPKDISLQIHKE
KILMVELFMKEEQGKR--------------------------------------------
>tr|A0A0R4IJ67|A0A0R4IJ67_DANRE Uncharacterized protein OS=Danio rerio GN=ano1 PE=4 SV=1
----------------------------------------QADEKPKDPKLWPYFKDGHRRIDYVLTYHIQKPQNTGKQ--S------------------
-SK-S-----------CL--GDDQRLRREEFEENLREMGLEMEKEEG-KIPGVGFLKIHAPWEVLCREAEFMKLKMPTIKKYEVSHGNSIVEKASRFMQK
FTAPLQPKVGDRQIEHEKHLSYPFSREKQHLFDLSDRNSFFDSKTRSSIVYEILKRTKCTRAKYIM-IISLLGNGIYTSAYPLHDGDIDDV-AEINDRKI
LYEEWASYSIFYKYQPIGLIRKYFGEKVGLYFAWLGVYTQMLIPAAIVGVIVFLYGCATVDDNIPSMEICDERNNITMCPMCDRACSYWKLVTACGTARA
SHLFDNAATVFFAIFMALWAAMFMEHWKRRQVRLNYLWDLTGFEDTE----SHPRAEYEFHVMKKSLRKEK----AGNVKLTCTDRMPAYMTIIITMIFL
ICVTLAIVFGVVLYRVSIMTALHMSSTPTFRSNIRATVKTTGAIINLIIIIIMDEVYGAVARWLTIMEVPKTDKSFEERLIFKTFVLKFANAFTPIVYLA
FFRG-LIGRPGKYIYVMGSYRMEECAHAGCLMELCIQLCITMLGKQLIQNNLFEIGVPKIKKLLRQRKID--PK-HQEELNKTLHRHEKDHFLGPFVGLN
PEYMEMIIQFGMVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPIAVRAKDIGIWYTLLRGLSKVAVIVNAFVISFTSDFIPRLVYQYMYSPDGT
LHGFVNHTLSYFNVTHFQPGTEPLEPMHLGYQVDTCRYKDYRDPPWSDTPYEFSREFWAILAARFAFVILFQNVVMLMSDFVDWLIPDIPKDISLKIHKE
RNLIIELFMKREQGKKYRNTMN--------------------------------------
>tr|S4R5B8|S4R5B8_PETMA Anoctamin (Fragment) OS=Petromyzon marinus PE=3 SV=1
-------------------------------------------------KGGPYMRDGKRRVDFVLAYHFKRHRSFPGSPTSE-----------------
-ENTATTL------EVIT--AKEQMICREEFEQNLMDARLELEWDEE-QAEGHGYLRIHAPWLVLIREAEFLKIKMPTKKVFEMKQSSGVLHGLG---AR
INHALQPNVPHSQEASQKKLSFPFSRDKQKLFDIKSEDSFFDSATRSRIVFEILKRVKCTKGPYKM-ITSLIANGVYTSAFPLHDGELH--GSEVNDRKL
LHDEWASYNKFYKYQPLELIKKYFGEKIGLYFAWLGVYTQMLIPPSVVGIAVFLYGWLAAEKDIPGFETCVIGQNITMCPTCDKLCKYKRLSENCDRVRS
SHLFDNITTVLFSIFMALWATTFLEHWKRIETRLNYTWDLNGMEESE----QQLRPEYEAKLLEKKRKVDI----TEEYGLSWRDQLPSFLINCSCILFM
VLLSFAIVVGMIFYRITMNVLLANSTDPYLKSNRSAIIMATAFLINLVIILILDEIYGSIARWLTVIEVPKTEEEFETRLIFKSFMLKFVNSYTSIIYVA
FLKG-ITGYPKKYYYILPNYRMEECAPGGCLQELALQLCIIMLGKQLLQNNLFEVGIPKIKKLCRYLHKKDHHKKEDG-----MELGCKDYELEPFTGLN
PEYMEMVIQFGFVTLFVASFPLAPFFALLNNVIEIRLDGKKFVTELRRPTAVRAKDIGTWYVILNGVAKLAVIINALVIALTSDFVPRLIYMYFYSPDGS
LRGYVNYTLSYFNVSDYAPGIIIES------NYTLCRYK-------------------------------------------------------------
------------------------------------------------------------
>tr|A0A087XTB6|A0A087XTB6_POEFO Anoctamin OS=Poecilia formosa PE=3 SV=2
----------------------------------------ASDGSLLHLPHGPYFSDGQRRVDYVLTYGIQKPSAVRRQ--S------------------
-SK-L-----------SD--NDDKRFKREEFEQNLQEMGLELEKDEG-KIAGIGFLKIHAPWAVLCREAEIMKLKMPTKQVYEVKQGSNLVEKIRLFIHK
VTDPLHPKVGPKRPEDVKSLSLPFSKEKQHLFDLSDRDKFFDSKTRSSIVYEVLKRIRWTRPNYSL-ITSLLANGVYTSAYPLHDGDIDGV-AEPNDRKL
LFEEWASYSVFYKYQPIGLIRKYFGEKVGLYFAWLGVYTQMLIPAAIVGVIVFLYGCATVDDNIPSMEICDPRNNITMCPLCDSACSYWKLETACGTARA
SHLFDNPATVFFSIFMALWAVLFMEHWKRRQMRLNYVWDLTDYGMEEEEYKDHNRAEYELRVAEKTMRQDQ----DEKVKLTCTDRMPAYLTTVVMMSFM
IFITFVIAFGVILYRISIKTALHLSTYPAARSNIRATVKTTAAIINVIVIIILDEIYASIARWLTTLEVPKTDKSFEERLIFKTFILKFVNAFTPIVYLA
FFRG-LVGRPGKYLYVVGSYRMEECAHAGCLMELCIQLCITMLGKQLIQNNLFEIGIPKLKKLLRKRKSELTSK-QEEELHKTLKRYEKDHVLGPFVGIN
PEYMEMIIQFGMVTLFVASFPLAPLFALLNNIIEIRLDAKKFVLELRRPIAAKVKDIGIWYNLLRGLSKVAVIVNAFVIAFTSDFVPRLVYQYTYSPDGT
MHGFVNHTLSYFNVSDFQNGTEPNPPNFNVKV---CRYKDYREPPWSNTPYELSKEFWAILAVRLAFVIVFQNMVMLMSDFVDWLIPDIPKDISFQIHKE
KLLMLDHFMKEEGRRRDNHNHDG-------------------------------------
>tr|H2L3M2|H2L3M2_ORYLA Anoctamin OS=Oryzias latipes GN=ano1 PE=3 SV=1
-------------------------------------------------KLGPYFRDGHRRVDYILEYSIQKPNSARRH--S------------------
-TI-F-----------GN--DDDKSNKRKEFEENLQEAGLELEWDEE-HVPGVGFLKIHAPWDILCREAELMKLKMPTKKTYEIKQGSNLVEKIRLFIHK
ATAPLHPKVESNQQPGLKHLSHPFSREKEHLFDLSNKDKFFDSKTRSSIVHEVLKRTKCERDHYSM-ITSLLANSIYMAAYPPHDGDINGM---RNDRRL
LYEEWASYSVFYKYQPVGLIRKYFGEKVGLYFAWLGVYTQMLIPASIVGVIVFLYGCATVDSNIPSMEICDPRNDIIMCPLCDRACSYWKLVTACGTARA
SHLFDNEATVFFSIFMALWAVLFMEHWKRRQMRLNYTWDLTGFGEEEEEHKDHNRAEYEIRVMEKTMRQDQSFCREEKVKLTCIDRMPAYMTVVAMMAFM
ITLSFTMAFGVILYRISIKAALHMASA-AGQSNIRATVKGTAAVINVVIIIILDEIYAKVARWLTILEVPKTDKSFDNRLIFKTFILKFVNAFTPIVYLA
FFRG-LVGRPGKYLYVVGSYRMEECAHAGCLMELCIQLCITMLGKQFIQNNLFEIGIPKLKKMLQKRKMD--PQ-EEEKQNKILPRHQKDHLLLPFAGLN
PEYMEMIIQFGMVTLFVASFPLAPLFALLNNIIEIRLDAKKFVKELRRPVAAKAKNIGIWYNLLRGLSKVAVIVNAFVIAFTSDFIPRLVYQYTYSPDGT
LHGFVNHTLSVFNVRDFEPNTQPIYPNHLGYNVETCRYKDYREPPWSSTPYELSKEFWSILAVRLAFVIVFQNVVMLMSDFVDWLIPDIPKDITLQIHKE
KIHMMELFMKEEQGKRR-------------------------------------------
>tr|I3KNV4|I3KNV4_ORENI Anoctamin OS=Oreochromis niloticus PE=3 SV=1
-----------------------------------------MKDLCPDTVLGPYFSDGMRRVDYVLTYHIQKSGSTRRR--S------------------
-SR-F-----------GD--NDDKRFKRDEFEENLRKTGLELEKDEE-TIPGIGFLKIHAPWNVLCREAEFMKLKMPTKKVYEVKQGSNVVEKIRMFIHK
VTAPLHPKVNTSRSQCEKPLCHAFSREKQHLFDLSDKNKFFDSKTRSSIVYEVLKRTKCMKPKYPL-LTSLLANGVYTSAYPLHDGDIVGV-AEPNDRKL
LYEQWASYSVFYKYQPIGLIRKYFGEKVGLYFAWLGVYTQMLIPAAIIGVIVFLYGCATVDDNIPSMEICDPRNNITMCPLCDQACSYWKLVTACGTARA
SHLFDNAATVFFSVFMALWAVLFMEHWKRRQMRLNYVWDLTGFGEEEEEHKDHNRAEYEFRVMQKKLKQEHARLSDEKVKLTCTDRLPAYMTTVVMMGFM
ITVTFVIVFGVILYRISIKAALHMSSHPVVRYNIRATVKTTAAIINLIIIIVLDEIYGAIARWLTRLEVPKTDKSFEERLIFKTFILKFVNAFTPIVYLA
FFRG-LVGRPGNYLYVVGSYRMEECAHAGCLMELCIQLCITMLGKQLIQNNLFEIGIPKLKKMLRKRKSELDSI-QEQVLHNTLKRYEKDQLLGPFVGLN
PEYMEMIIQFGMVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPIAAKAKDIGIWYNLLRGLSKVAVIVNAFVIAFTSDFIPRLVYQYMYSPDGT
LHGFVNHTLSYFNVTDFDPGTEPLQPMHLGYKVSVCRYKDYRDPPWSSTKYELSKEFWAILAARLAFVIVFQNVVMLMSDFVDWLIPDIPKDISLQIHKE
KILMVELFMKEEQGKR--------------------------------------------
>tr|H3B4R3|H3B4R3_LATCH Anoctamin OS=Latimeria chalumnae GN=ANO3 PE=3 SV=1
----------------------------------------LQEDLRSTAPSGLFFKDGKKRIDYILVYKKSSPQ--------------------------
------------------------IEKRSTFEKNLRAEGLMLERE---TNSDIMYVKIHTPWDTLCKYAERMSIRMPFRKK--------AMDR-----FH
--QPMKLDKEALP--ETDCYTAPFSRA----FTINNRDSFFSNSTRSRI-HHVLQRTKYEDG-----IVKKPGTGGHFQGIPPHE----RHHGAQNHRHL
LYERWARWGMWYKYQPLDLI-RYFGEKIGLYFAWLGWYTGMLIPAALVGLLVFLYGVFTTE---SSREICEA-NDTIMCPMCDRTCSFWNLSDSCVYAKV
THLFDNGGTVFFAIFMAIWA-VFLEFWKRRRAVLTYDWDLIDWEEEE-------RPQFEA------KY---VNPEPFT-------KLSRL-VSVSGIFFM
ISLVLT-VFA-VVYRLVAMEQFASFWDFI-R--QF-ATSGTGVCINFMIIMSL-VVYEKVAYLLTNL--PRTESEWENSFALK---FQFVNLNSSIFYIA
FFLG--AGRPGKYNKLFE--RLEECHPSGCLIDLCMQMGIIMVLKQMW-NNFMEG-YPLLQNWWSRRKIKRGG--QTMDNKVFLPQWEKDWNLQPMHGLM
D--LEM-LQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPMPARATDIGIWYGILEGIGILAVITNAFVIAITSDYIPRLVYAFKYGP-KC
LKGYMNSSLSVFDMSDLGG-N---D-------SGYCRYRDYRAPPWSSAPYEFTLQFWHVLAARLAFIIVFEHLVFGTKSFIAYLIPDMPKDLCDRMRRE
KYLVQEMMYEAELEHLQKDRK---------------------------------------
>tr|A7RKU7|A7RKU7_NEMVE Anoctamin OS=Nematostella vectensis GN=v1g159852 PE=3 SV=1
----------------------------------------N---DNTVGPTGRFFNKGGHKVDYVLVYETCQEREDKDPKF-------------------
---------------------ADFERKRDAFEAALSEQGLVIERESITDKVKRHFVKLHVPWRTLSSKAEELMLKAPLQND-------------------
---PFRIKDSSIP--KPKCFMAYFKERKVDKYMGAEPEKMFTALDRHYV-QRICYATRFAEG-----LKQLVYEGAYCANYPLHD-------YPSNDRQR
LKKDWSSMKRIFKYQPLDTVKGYYGTAIALYFAWLGFYTAMLIPLAIVGLLVFIYGIGSSA-SPTVRDACDTNNKFYMCPLC-RTCSYWDLVTTCMYARV
THFFDNDGTVFLAIFTSVWA-LFLEFWKRRQAVLAYEWHVANFEEEE----EQIRPEFAATAP---T----KNLEPR------RTLYQRYGAIGSVVAFM
ILLVIA-VIG-VVYRAAVFAALSGNSDSTIRIGSRIITSMTAALINLLCINILKLFYNRLAVWLTNWENPRTKTDYEDSFTYK---FQFVNTYASIFYIA
FFKS--VVGTPGRYK-----RLEGCSAQGCFLELCVQMLIIMVGQQII-GNITEVAIPAIMTWIKERK---------EPKNKQLPQFEQDYNLQPQHNLF
WEYLEIVLQYGFVTMFIAAFPLAPLFSLLNSIVEIRVDAINFVSQFRRPDTMIAEDIGAWYRILETLTRLSVLINAFVLSFTSEFIPKLVYKLKYAPEGT
LEGYLNNSLSAINVTEWEPGTAP-------NYETFCRYKGYHDNT----PFKFNKQYWHVIAARLAFVFVFQYTVYAITSFIAWAVPDQPRSLELRSKRE
EHLTKKILYNKG-RSGR-----L-------------------------------------
>tr|F7AK56|F7AK56_CALJA Anoctamin OS=Callithrix jacchus GN=ANO2 PE=3 SV=1
----------------------------------------E-PVSSEARLSRMHFHDNQRKVDYVLAYHYRKRGAHLA----Q-----------------
-GSLGHSL------AIIS--NEERKEQREEFEHNLMEAGLELEKDLE-KSQGSIFVRIHAPWQVLAREAEFLKIKVPTKK-YEIKAGGSIAKKFSAVLQK
LSSPLQPRVPEH-SNKMKNLSYPFSREKMYLYNIQEKDTFFDNATRSRIVHEILKRTACSRANNTM-INSLIANNIYEAAYPLHDGEYDS-EHEMNDRKL
LYQEWARYGVFYKFQPIDLIRKYFGEKIGLYFAWLGLYTSFLIPSSVIGVIVFLYGCATIEEDIPSREMCDQQNAFTMCPLCDKSCDYWNLSSACGTARA
SHLFDNPATVFFSIFMALWA-MFLENWKRLQMRLGYFWDLTGIEEEEVNTHEHSRPEYETKVREKMLKESNTNDDDDEDKLTWKDRFPGYLMNFASISFM
IALTFSIVFGVIVYRITTAAALSL--NKATRSNVRVTVTATAVIINLVVILILDEIYGAV-KWLTKIEVPKTEQTFEERLILKAFLLKFVNAYSPIFYVA
FFKG-FVGRPGNYVYVFDGYRMEECAPGGCLMELCIQLSIIMLGKQLIQNNIFEIGVPKLKKLFRKLKDE-TE-GTDSAHSKHPEQWDLDYSLEPYTGLT
PEYMEMIIQFGFVTLFVASFPLAPVFALLNNVIEVRLDAKKFVTELRRPDAVRTKDIGIWFDILSGIGKFSVISNAFVIAITSDFIPRLVYQYSYSHNGT
LHGFVNHTLSFFNVSQLKEGTQPENSQFD-QEVQFCRFKDYREPPWAPNPYEFSKQYWFVLSARLAFVIIFQNLVMFLSVLVDWMIPDIPTDISDQIKKE
KSLLVDFFLKEEHEKLKLMDEPG-------------------------------------
>tr|F6WXA5|F6WXA5_XENTR Anoctamin (Fragment) OS=Xenopus tropicalis GN=ano1 PE=3 SV=1
----------------------------------------LGTDQDSACKHGLYFRDGQKKVDYILAYTYKKSSGSRTPNKKN-----------------
-HHS-------------N--SDDKRFRREEYEGNLIETGLELERDEETKQHGVGFVKIHAPWNVLCREAEFMKLKMPTKKFYQINQTPGLMQKLSSFIQK
ISEPIQPKVAGLRPQTVKPLSYPFSREKQHLFDMSDKDSFFDSKTRSSIVYEILKRTTCTKAKYSMVITSLLANGVYSAAYPLHDGDYESE-AEANDRKL
LCDEWASYSVFYKYQPIDLVRQGVAEDLGLTHHSRLCYLQLLYYAKKAILLRFPWRCVTIDTTLPCMEMCDNRYNITMCPLCDRTCNYWKMSSACGTARA
SHLFDNPATVFFSVFMALWAASFMEHWKRRQMRLNYRWDLTGFEEEEGMVKDHPRAEYEAKVLQKSLKKEYVPAGTEKEKLTWRDRFPAYLTNVVGIIFM
IGVTFAIVFGVIMYRISTAAALAMSSNPNTRANVRVTVTATAVIINLVVILILDEVYGAIARWLTQIEVPKTDQTFEERLIFKAFLLKFVNAYTPIFYVA
FFKGRIVGRPGDYYYIFQSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKSKRQSYKDHEEHLKKKQRYEEDYDLEPFAGLT
PEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFITELRRPVAVRAKDIGIWYNIIRGLGKLAVIINAFVISFTSDFIPRLVYLYMYSPDGT
MHGFVNHTLSYFNVTDFKPGTEPSEPVDLGYKVELCRYKDYREAPWSPHKYDINKDYWAVLAARLAFVIVFQNLVMFMSDFVDWIIPDIPKDISEQIHRE
KVLMVEVFLKEEQGKLQMLETWK-------------------------------------
>tr|W5LPJ9|W5LPJ9_ASTMX Anoctamin OS=Astyanax mexicanus PE=3 SV=1
----------------------------------------G-----HEPGKGLYFADGKRKVDYVLVYQYRRPSSVHD----S-----------------
-PGQHRL-------SVIS--NGEKLMIREEFEANLREAGLEMERD---KVHGQGFIRVHAPWQVLSREAEFLKIKVPTKKSYELKEEKGLSGTMSTIWRK
MNQPFQPKVPNLQ-DRTKYLSHSFSRDKLHLYNIESKDTFFDNATRSRIVYEILRRTACTRTCQTM-ITTLIAKGVYDSAFPLHDGDFKGESEDKNDRQL
LHDEWARYGAFYKYQPVDLIRKYFGEKIGLYFAWLGVYTQLLALASLVGIIVFLYGCFTIDSNVPSLEMCDEKQNFTMCPLCDRACEYWHLSTACGTARA
SHLFDNPATVFFAIFMSLWAVMFLEHWKRRQNSLNYSWNMTGMEEEE----EHPRPKYETILLQKRQRKRRSETTPGDEKLTWKDRMPGYFINISSILLM
FGVTFAAVFGVIMYRITVSALLAMSPDAQIKSNVRVTVTATAVIINLVVILILDEIYGSVAVWLTELEIPKTETNFEERLILKAFLLKFMNAYAPIFYVA
FFKG-FAGRPGDYVYIFNDYRMEECAPGGCLIELCIQLSIIMLGKQLIQNNVFEIAIPKLKKLFRTIKEKKMI-EREEQAGRTLRQWHLDYNLEPFDGLT
PEYMEMIIQFGFVSLFVASFPLAPLFALLNNVIEIRLDAKKFVTELRRPDAVRAKDIGIWYNILSGMGKFSVIINAFVISFTSDFIPRLVYQYMYSETGT
MHGFIDHTLSYFNVSHFKEGTAPSGST-----ITVCRYKDYREPPWSGTPYQFSKHYWSVLAARLAFVILFQNLVMFMGLLVAWVIPDVPKNISEQLKRE
KTLLVDVFMNEEKEKLQLIQSLF-------------------------------------
>tr|A0A0R4IKC5|A0A0R4IKC5_DANRE Uncharacterized protein OS=Danio rerio GN=ano2 PE=4 SV=1
----------------------------------------D-----QDPRKRLYFADGRRKVDYVLVFHYRKRSSIRGS---------------------
-PSQHRL-------SIIS--NGEKIMIREEFEGSLKDAGLEIERD---KAHGHAFIRLHAPWQVLSREAEFLKIKVQTKKSYELREEKGLAATMNEVWRK
LNQPFQPKVPHQEQERTKFLTHCFSRDKLHLYNIQSKDTFFDNATRSRIVYEILRRTACTRTCQTM-ITTLIANGVYDSAFPLHDGDFHSSAEGKNERQL
LHDEWARYGAFYKYQPIDLIRKYFGEKIGLYFAWLGVYTQLLIPASVVGIIVFFYGWATVETNVPSQEMCDETQNFTMCPLCDRVCDYWQLSTACGTARA
SHLFDNPATVFFAIFMSLWAAMFLEHWKRRQISLNYSWDLTGMEEEE----EHPRPKYETILLQKRQRKKKNEAATGHEKLTWRDRLPGYLINISSILFM
FGVTCSAVFSVIIYRITISALMAMSPDPDVKSNVRVTVTATAVIINLVVILILDEIYGMVAAWLTELEIPKTETNFEERLILKAFVLKFMNAYAPIFYVA
FFKG-FAGRPGDYVYVFHDYRMEECAPGGCLIELCIQLSIIMLGKQLIQNNVFEIGIPKLKKLCRTLKDKDRE-KIVEQ-PGRRQQWHMDYDLEPFDGLT
PEYMEMIIQFGFVSLFVASFPLAPLFALLNNVIEIRLDAKKFVTELRRPDAVRTKDIGIWYNILSGLGKFSVIINAFVISFTSDFIPRLVYQYMYSETGT
MHGFINHTLSYFNVSNFKPGTMPSTSD-----ITVCRYKDYREPPWSNEPYQFSKQYWSVLAARLGFVILFQNLVIIMSMLVAWLIPDMPKNISEQLKKD
KTLLVDVFLNEEKEKLQLIQSLF-------------------------------------
>tr|W5NKC5|W5NKC5_LEPOC Anoctamin OS=Lepisosteus oculatus PE=3 SV=1
----------------------------------------Q-----PDTRNGLYFSDGKRKVDYVLAYHYRKRSPP----LST-----------------
-PGALGL-------AVIS--NEEKMRSREEFEKNLMEAGLEMEKD---KIQGIGFVRLHAPWLVLSREAEFLKIKVPTKKVYEVKEEGGVMATLNSAWDT
ITKPLQPKVPHLQ-SKTKYISHSFSREKLHLYNISEKETFFDNATRSRIVYEILKRTSCIRTCQST-ITTLIANGVYDSAFPLHDGTF---TEEKNERQI
LHQEWARYGAFYKYQPVDLIRKYFGEKIGLYFAWLGVYTQLLIPASLVGIIVFFYGCATVDTDIPSLEMCNEDKNFTMCPLCDGPCDYWHLSTACSTARA
SHLFDNPATVFFSVFMSLWAAMFLEHWKRRQMRLSYRWDLTGLEEEEDRVKEHPRPKYETKLLQKRQKKRRSEGGVGKEKLTWKDRMPGYIINFTSILFM
FGVTFSAVFGVIVYRIITSAIIAMSPDPQTKANVRVTVTATAVIINLVVILILDEIYGAVATWLTEIEIPKTEKDFEERLILKAFLLKFMNSYAPIFYVA
FFKG-FVGRPGDYVYIFNHYRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKLKKLYRKLRDKGTA-ETDD-NQRLSRQWDLDYNLEPFTGLT
PEYMEMIIQFGFVSLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPDAVRAKDIGIWYNILSGMGKFSVIINAFVISFTSDFIPRLVYQYMYSETGT
MHGFIDHTLSYFNVSHFKPGNAPTLSQYD-KEVTVCRYKDYREPPWSPNAYDFSKQYWSVLAARLAFVILFQNLVMFLSELVDWMIPDIPKDISEQIKKE
KTLLVDVFLKEEKEKLQLIQSLF-------------------------------------
>tr|A0A0Q9W634|A0A0Q9W634_DROVI Uncharacterized protein, isoform D OS=Drosophila virilis GN=Dvir\GJ18522 PE=4 SV=1
----------------------------------------------WKLRTYRRFNDGRRSVDFVLAYKGEDVD--------------------------
---------------------EVAASKRRIFEANLMSEGIQLEYYK---EQWVHFVKLHAPAEVLYRYAEILKIKMPLKIPEQIADTPDFKT-VSRICRS
LFSSVQLNTELFP-ERTPRIHLEFARKYLELYDE-EHPNFFDESTRYSIINFIMQRQQFEGGEDNLGIEKLIEDGVYLCAYTLHDKD---------TRGK
LLKEWANIGKWKNLQPLDHIKDYFGPKVALYFAWLGFYTQMLIPVSILGILFFVYGFLTWNSDPISFDICNDNET-IMCPQCDRGCKFWSLNETCTSSRF
NYLIDNQMTMVFAFVMAIWAVIYLELWKRYSAGLVHRWGLTGFNHHV----EHPRPQYLAKISNSKRSDKLKTFD--PDVPFWSTKFLPNFTSYSIMVLF
ICISLIAVAAIIIYRMAQRASHTILANENTMTYRIMVLPITAGFLDLIVISILDMVYSKLAVRLTNYEYCRTQTEYDESLTIKNYVFQFVNYYSSLFYIA
FLKGKFVGYPSKYNRIF-SFRQEECNPGGCLMELCVQLVIIMVGKQAV-NAIVEILIPFLMRTAKEFSQRYDWYRSEQKLVPSTNQFTEDFNLLPTSSLY
EEYLEMVVQYGFITLFSLAFPLAPLLALINNVIEVRLDAIKMLRFMRRPVGMRARNIGVWQSIMTVVTHIAVASSAMIIAFSSNFIPKLVYKAT-HDDPE
LNNYLNFTLATFYTKDYGTQSLLDVSVQ--ANVTECRYIEFRNDPWENPPYKRPMIYWKILTARLAFIVIYQNIITMLQGILRWAVPDVSGRLLKRIKRE
NFLLREHIIEYEKRQAQEVTQSQ-------------------------------------
>tr|B4JJD6|B4JJD6_DROGR Anoctamin OS=Drosophila grimshawi GN=Dgri\GH12469 PE=3 SV=1
-----------------------------------------------DDETYRRFNDGKRSVDFVLAYKGEDVD--------------------------
---------------------KTA--RRTKFEDNLRREGLELEYYK---EQWVHFIKLHAPVEVLHRYAEILKIKMPLKIPKDIIDERDLNTCFSRLCRT
LFSSVQPDTVKFP-IRQPRIHMEFACKYLELYDK-EHPNYFDASTRYSIINFIIERQHFERGEENLGFEKLVEDGVYLCAYALHEKD---------ERDN
LLMGWANIGKFKNLQPLDHVKDYFGPKVALYFAWLGFYTQMLIPVSILGILFFLYGFVTWNSDPISQDICNGNDT-IMCPQCDKGCMFWRLSETCTSSRF
NYLIDNEMTLVFAFIMAIWAVTYLELWKRYSAGLVHRWGLTGFNQHV----EHPRPQYLAKVASSKKNAETRSFD--PYVPFWSIKFFPNFTSYSIMVLF
ICISVIAVSAIIIYRMAQRASHSILGNENSMTYKIMVLPITAGFLDLIVISILDLVYSSLAVKLTNYEYCRTQTEYDESLTIKNYVFQFVNYYSSLFYIA
FLKGKFVGYPSKYNRIL-SFRQEECNPGGCLMELCVQLVIIMVGKQAV-NAIVEMLIPYLRRTARECNQRHGWFKSDEIVVPSTNQFTEDFNLQSTNSLY
AEYLEMVVQYGFITLFSLAFPLAPLLGLINNVMEVRLDAIKMLRFFRRPVGMRARNIGVWQGIMTVVTHIAVASSAMIIAFSTNFIPKLVYKHT-HDDPE
LNNYLNFTLATFYTKDYTTQTLLDVSAQ--ENITQCHYTEFRNAPWLDQPYKRPMIYWKILTGRLAFIVIYQNIIALVQGIIRWAVPDVSARLLKRIKRE
NFLLREHIIEFEKRKAHELAQTP-------------------------------------
>tr|A0A0M4EX25|A0A0M4EX25_DROBS Anoctamin OS=Drosophila busckii GN=Dbus_chrXg48 PE=3 SV=1
----------------------------------------------WKLRTYRRFNDRERSVDFVLAYHVNKQQ--------------------------
---------------------DVAIRKRQIFEANLMREGLQLEHEQ---VQLMHFIKLHAPAEVLQRYAEILKIKMPLKIPEQIEETHEFKTCLSRLCRS
MFSSVQLNTELFP-ERAPRIHMEFADKYAELYDK-QHPNYFDASTRYTIINFILQRQHFVMGEDNLGVEKLINDGVYQCAYTLHDEV---------DRSR
LLKEWANIGKWKNLQPLDHIKDYFGAKVALYFAWLGFYTQMLIPVSVLGILFFLYGFVTWNSDPISQDICNGNET-VMCPQCDRDCNYWRLNETCTSARF
NYLIDNSMTVFFALVMAIWAVVYLELWKRYSAGLVHRWGLTGFTHHA----EHPRPQYLAKVSNSKRKAKLKSLD--PDVPFWSIKFLPNFTSFSIMVLF
MCISIIAISSIIIYRMAQRASNSILGNENSMTYKILVMPMTAGFLDLIVISILDMVYRMLAVKLTNYEYCRTQTEYDESLTIKNYVFEFVNYYSSLFYIA
FLKGKFVGYPAKYNRIL-GFRQEECNPGGCLMELCMQLIIIMVGKQAV-NAIVEMLIPYLMRTFKEFSYRYGWMK--EQKLVPHNQYTEDFHLLPANSLY
AEYLEMVVQYGFITLFSLAFPLAPLLALINNVMEVRLDAIKMLRFLRRPVGMRAHDIGVWHNIMIVVTRIAVASSAMIIAFSTNLIPKLVYRAT-HDDPE
LSNYLNFTLATFYTKDFQVQPLLLDSSY--SNITECRYTEFRNNPWEQQPYKRPMIYWKILTARLAFIVVYQNIITMLQGILTWAVPDVSGRLLKRIKRE
NFLLREHIIEFEKQRAAAQAQTP-------------------------------------
>tr|A0A0Q9XSV7|A0A0Q9XSV7_DROMO Uncharacterized protein, isoform C OS=Drosophila mojavensis GN=Dmoj\GI11145 PE=4 SV=1
----------------------------------------------WKSRTYRSLKDG-RSVDFVLAYNGDDSD--------------------------
---------------------TAAKKQREIFEENLKREGLVLEPYD---QQWVHFTKVHAPMPVLERYAEVLKIKMPMKIPEQIAEQRELKTCWSRMCRR
LFSSVQLNNEVFP-ERSQRIHMEFARKYLELYDK-EHPNYFDDSTRYSIINFIMQRQHFEKGDESLGIEKLIEDGVYLCAYALHDKV---------KRDD
LLKEWASLRNWKKMQPLDHIKDYFGAKVALYYAWLGFYTQMLIPISVLGILFFLYGFVTWNSDPISYDICKGNET-IMCPQCDRGCKFWHLNETCASSRF
NYLIDNKMTMVFAFVLSIWAVAYLELWKRYSAGLVHRWGLTGFNHHV----EHPRPQYLAKLRKSKKKDTPKTFD--PDVPFWSFKFLPNFTSYSIVVLF
ICISLIGVAAIIIYRMAQRASSSIIGNEDSMTYKIMVLPITAGFLDLLVISVLDLVYSKLAISLTNYEYCRTQTEYDESLTIKNYVFQFVNYYSSLFYIA
FLKGKFVGYPSKYNRIF-SFRQEECNPGGCLMELCMQLVIIMGGKQAV-NAVIEMLIPFLMRVFNELSQRYDFLKNEK-KVPSINQFTEDFNLLPANSLY
EEYLEMVVQYGFITLFSLAFPLAPLLALINNVIEVRLDAIKMLRFVRRPVGMRARNIGVWQNIMAVVTHISVASSAMIIAFSTNFIPKFVYKAT-HDDPE
LDGYLNFTLAAFYTKDYKTQSLLDASNA--ANVTLCHYIEFRNDPWVDPPYKRPMIYWKILMARLAFIVIYQNIISMLQGILRWAVPDVSARLLKRIKRE
NFLLREHIIDYEKSQVQEITQQQ-------------------------------------
>tr|A0A0Q5T3J8|A0A0Q5T3J8_DROER Uncharacterized protein, isoform F OS=Drosophila erecta GN=Dere\GG18823 PE=4 SV=1
----------------------------------------------EPATTYRRFDDGKRSVDFVLAYNGETQL--------------------------
---------------------EEHRRKCEIFEANLQREGLQLEHNK---VQRVHFIKIHAPTEVLYRYAEILKIKVPLKIPDQIAEAHEFKTCCSRMCKS
LFSSVQLNTALFP-EREPRIHLEFSRNYLELYDT-EHPNFLDASTRYSIINFILQRQHFVEGEDNLGIEKLVQDGVYTCAYTLHDKD---------DRER
LLKEWANISKWKNLQPLDQIKDYFGAKVALYFAWLGFYTQMLIPISIFGVLCFLYGFVTWSSDPISRDICDDNGT-IMCPQCDRSCDYWRLNETCTSSKF
NYLIDNNMTVVFAFSMAIWAVVYLEFWKRYSAGLVHRWGLTGFTHHV----EHPRPQYLAKISRTKRAGKARNLD--PDVPFWSIKFLPNFTSYSIMVLF
ICISVIAIAGIIIYRMAQRASHSILGSENSMTFKVMILPMTAGIIDLIVISLLDMVYSNLAVKLTNYEYCRTQTEYDESLTIKNYVFQFVNYYSSLFYIA
FLKGKFVGYPAKYNRVL-GFRQEECNPGGCLMELCMQLVIIMAGKQVV-NAIVEMLIPYLMRTFKELSYRHGWYK--DQRLVPYNQFTEDYNLLPANSLY
AEYLEMVVQFGFITLFSLAFPLAPLLALLNNVIEVRLDAIKMLRFLRRPVGMRARDIGVWHSIMTVVTRIAVASSAMIIAFSTNLVPKIVYAAS-MGDPE
LNNYLNFTLAVFNTKDFQVQPLLGGSQH--VNETVCRYTEFRNPPDDPHPYKRPMIYWKILTGRLAFIVIYQNIITMMQGILRWAVPDVSGRLLKRIKRE
NFLLREHIIEYEKQHAMKMVQTE-------------------------------------
>tr|B4NDR8|B4NDR8_DROWI Anoctamin OS=Drosophila willistoni GN=Dwil\GK25421 PE=3 SV=2
----------------------------------------------WKLRTYRRFNDGKRSVDFVLAYNGEDLI--------------------------
---------------------EEHRRKREIFEANLQREGLELEHYV---GQRVHFIKLHAPLQVLYRYAEILKIKLPLRIPEQIEEEHEFKSCLTRMCRS
LFSSVQLNTALFP-EREARIHLEFSQKYLELYDT-EHPNFFDASTRYSIINFILQRQHFVEGEDNLGVEKLIQDGIYTCAYTLHDKE---------ERDR
LLKEWANIGKWKNLQPLDHVKDYFGAKVALYFAWLGFYTQMLIPVSIIGIICFIYGFITWNSDPISRDICNDNGTTIMCPQCDRSCDYWKLSETCTSSKF
NYLIDNSMTVVFAFVMAIWAVVYLEFWKRYSAGLVHRWGLTGFNHNV----EHPRPQYLAKISRSKKAQKAPNLD--PDVPFWSIKFLPNFTSYSIMVLF
ISISIIAIAAIIIYRMAQRASSSILGSENSMTYKVMVLPMTAGIIDLVVISILDLVYSKLAVKLTNYEYCRTQTEYDESLTIKYYVFQFVNYYSSLFYIA
FLKGKFVGYPAKYNTVL-GFRQEECNPGGCLMELCMQLVIIMVGKQIV-NAVIEMLVPYLMRTIKRYIQHYNWYRHEEPRLVPCNQFTEDYNLLPMDSLY
AEYLEMVVQYGFIILFSLAFPLAPLLALINNAIEVRLDAIKMLRFFRRPVGMRARDIGVWHNIMTVVTRIAVASSAMIIAFSTNLIPKLVYKHS-TGDHE
LNNYLNFTLAYFNTQNFQSPPISTSSQY--ANITECRYTEFRNPHWDEHPYKRPMIYWKILTIRLTFIVVYQNIISMLQGILRWAVPDVSGRLLKRIQRE
NFLLREHIIEYEKHQAQAQLQVQ-------------------------------------
>tr|A0A0Q9WGN2|A0A0Q9WGN2_DROVI Uncharacterized protein, isoform B OS=Drosophila virilis GN=Dvir\GJ24534 PE=4 SV=1
----------------------------------------------AELNTSLFFEDCTRSIDFVLAHTINAHEPT------------------------
--------------------E-ENAEKRRVFQENLVQQGLEVELSQ---KDQIYFVKIHAPLEVLRRYAEILKLRMPMVIPSVVRSTKSVYSSLKTVCQF
FMRNIYVDEQYFP-RRAHRFTAIYSRDKEYLFDI-RQDCFFTTAVRSRIVEFILDRQRFPAKRMAFGIERLVAEGVYCAAYPLHDGE---------IREL
LYTNWASVKKWYRYQPLDDIKEYFGVKIGLYFAWLGYYTYMLLLASIVGVACFLYSWISLKNYVPVKDICLRNSNITMCPLCD-WCEFWNLKETCNYAKI
TYLIDNPSTVFFAVFMSFWATLFLELWKRYSAEITHRWDLTGFDVHE----EHPRPQYLARLEHIEPTRTDTNKE--PTVPFWRMKLPATVFSFSVVVLL
IALAFVALVAVVVHRMSMLAALKVDGSGMTTSKAIVLAAASAAFVNLCLLYVLNYLYNHLAEYLTELEMWRTQTQFDDSLTLKIYLLQFVNYYASIFYIA
FFKGKFVGHPGEYITVF-KYRQEECSSGGCLTELCIQLAIIMIGKQAF-NTILEVYLPMFWR--KVLAIQVGLSRGNKPDKTKDERWMRDFKLLDWRSLF
PEYLEMVLQYGFVTIFVAAFPLAPFFALLNNILEMRLDAKKLLTHHKRPVSQRVRDIGVWYRILDCIGKLSVITNGFIIAFTSDMIPRLVYRSLKSPDGT
LNGYLDFTLSEFRISDSSKLQSLA-GDF--SNITTCKYTDYREPPTSPEKYHLTSMYYIILACRLGFVVVFENFVALVMILVRWCIPDMSVELRDQIRRE
VYITNEIIIDQEAQRARFERAKR-------------------------------------
>tr|B4JYY8|B4JYY8_DROGR Anoctamin OS=Drosophila grimshawi GN=Dgri\GH22385 PE=3 SV=1
----------------------------------------------AELNTSLFFADCKRSIDFVLAYKINSHAPT------------------------
--------------------E-EYADKRRIFEERLIKQGLEVEISH---LDQIYFVKLHAPLEVLRRYAEILKLRMP--IPSVVTSTKSVFSSLKTVWQF
FLRNIYVDENLFP-KRAHRFTAIYSRDKEYLFDI-RQDCFFTTAVRSRIVEFILDRQRFPAKRMAFGIERLIAMGVYCAAYPLHDGD---------IREL
LYTNWASVKKWYRYQPLDDIKEYFGVKIGLYFAWLGYYTYMLLLASIVGLACFLYSWISLKNYVPVKDICLRNVNITMCPLCE-WCEFWDLKETCNYAKI
TYLIDNPSTVFFAVFMSFWATLFLELWKRYSAEITHRWDLTGFDVHE----EHPRPQYLARLKNIKPTRTDTNKE--PTVPFWRMKLPATVFSFSVVLLL
IASAFVALVAVVVYRMSLVATLNNDRSGMTTSKAIVVATSAAAFVNLCLLYVLNYLYSHLAEYLTELEMWRTQTQFDDSLTLKIYLLQFVNYYASIFYIA
FFKGKYIGHPGQYIKVF-QYRQEECSSGGCLTELCIQLAIIMIGKQAF-NTILEVCLPMFWR--RVLVIKVGLKKGNKPNKGKDERWMRDFKLLDWRSLF
PEYLEMVLQYGFVTIFVAAFPLAPFFALLNNILEMRLDAKKLLTHHKRAVSQRVRDIGVWYRILDCIGKLSVITNGFIIAFTSDMIPRWVYRYK-SENGS
LDGYLDFTLSEFKISDSAELRRLA-SDS--SNITTCKYTDFREPPNSPNQYTYSDMYFIILACRLAFVVVFENFVALVMIFVRWCIPDMSVELRDQIRRE
IYITNEIIINQEAQRARFERSRR-------------------------------------
>tr|A0A0M4EP19|A0A0M4EP19_DROBS Anoctamin OS=Drosophila busckii GN=Dbus_chr3Rg2215 PE=3 SV=1
----------------------------------------------PELNTSLFFDDCTRSIDFVLAYKINANELL------------------------
--------------------E-DNAEKRRVFQENLIHQGLEVELSK---KEQIYFLKIHAPLEVLRRYAEILKLRMPM-IPSVVRSTKSVYSSLKGIFQF
FLRNVYIDENYFP-KRAHRFTAIYSRDKEYLFDI-RQDCFFTTAVRSRIVEFILDRQRFPAKRMAFGIERLISEGAYAAAYPLHDGE---------IREL
LYSNWASVRKWYRYQPLDDVKEYFGVKIGLYFAWLGYYTYMLLLASIVGVACFIYSWVTLKNYVPVQDICLRNTNITMCPLCD-WCEFWNLRETCIYAKI
TYLIDNPSTIFFAVFMSFWAALFLELWKRYSAEITHRWDLTGFDLHE----EHPRPQYLARLEHIEPTRTDTNKE--PTVPFWRMKLPATVFSFSVVVLL
IALAFVALIAVVVHRMSVLAALKVDGSNMTTSKAMILATASAAFVNLCFLYILNYLYNHLAEYLTEMEMWRTQTQFDDSLTLKIYLLQFVNYYASIFYIA
FFKGKFVGRPGEYNEVF-HYRQEECSSGGCLTELCIQLAIIMIGKQAF-NTILEVYLPMFWR--RVLAIQVGLSRGNKADKSKDERWMRDFKLLDWRSLF
PEYLEMVLQYGFVTIFVAAFPLAPLFALLNNILEMRLDAKKLLTHHKRPVSQRVRDIGVWYRILDCIGKLSVITNGFIIAFTSDLIPRLVYRYR--HNGS
LVGYLDSTLSEFLIVDSPKLHSLA-GDN--TNITTCRYADFREPPSSTEKYHLTRDFYIILACRLAFIVVFENFVALVMIFVRWCIPDMSVELRDQIKRE
VYITNEIIIEQEAKRARFARIRR-------------------------------------
>tr|A0A0M8ZZT9|A0A0M8ZZT9_9HYME Anoctamin OS=Melipona quadrifasciata GN=WN51_00448 PE=3 SV=1
----------------------------------------------CGTAFSLYFRDEIRTIDFVLVWDEYNMEAQ------------------------
-------------------TY-RCTEHRRVFEKNLEKESLQLEYEQA-EPNGLHFIKIHAPREVLRRYAEILKLRLP---SIIPNSSNV-----------
------------------LIKEVNSRDKEYLFNL-DSPNFFTAATRARIIQFILDRTRLIETKFAFGIERLISEKAYVAAYPLHDGD---------LRYL
LYKEWASLKKCLHYQPLDYIKEYFGVKIGLYFAWLGFYTHMLIPASIVGLLCFIYSCATLYSNEPSEDICNGNGTIEMCPLCDHICGYWDLKETCLHARI
TYLFDNPSTVFFSIFMSLWATLFLELWKRYSAEITHKWDLTGLDAQE----EHPRPQYLARLAHIKKKSLNTNEE--PKVPFWKMRVPATILSFSVVLLL
IAIAMAAVLAVVLYRMSVLTALSVYGHPMVTSYAILFTTATAASINLCCIIVFNWVYVWLAEYLTEIELLRTQTEFDDSLTLKIYLLEFVNYYASIFYIA
FFKGKFVGYPGNYNRFF-QYRQEECGPGGCLMELCIQLSIIMVGKQTM-NTILEMLFPLFYKWLNTLKVHVGMK-DGKVTTRKYLQWIKDYKLVEWRSLF
PEYLEMVLQYGFVTIFVAAFPLAPFFALLNNIFEMRLDAKKLLVMYRRPVGQRVIDIGIWYRILDSISKLSVITNAFIIAFTSNFIPRLVYRITVSDNYS
LEGFLDHSLSKFNTSDLQNGTKPFLPTH--KQVEICRYPDYRESPDSQNKYQYTIMFWHVLAARLAFIVVFENIVALVMILVRWCIPDMHPKLRDKIRRE
AYITNEIIIQQEALRASERSADD-------------------------------------
>tr|D6WLJ8|D6WLJ8_TRICA Anoctamin OS=Tribolium castaneum GN=TcasGA2_TC014363 PE=3 SV=1
----------------------------------------------SCRIPTIYFNDGMRSVDFVLVWDAFREDAT------------------------
--------------------T-EAYQKRKLFENNLVRDGLELEYVPQ-ESNGLNFIKIHAPKEVLRRYSEILKLRMPL-MPRQMSRTNFIVEGITSQWDK
LKSYVIVDSEKFP-EKDQRFTAIYSRDREYLFDV-DSPCFFTPAIHSRIVQFILDRKRFSDNHFAFGIERLLNDSVYSAAYPLHDGD---------LRYL
LYNEWTALSKWYRYQPLDYVKEYFGVKIALYFAWLGFYTHMLLPAAVVGLACFIYSCVTLYYNKPSEDICNGNFTFKMCPLCNHWCNYWDLKETCTHARI
TYLFDNATTVFFAIFMSFWAALFLELWKRYSAEITHRWDLTGFDIQE----EHPRPQYLARLAHVKRQEVNTNME--PHVPFWRLRVPVTIFSFSVVMLL
VTLALATVVAIVVYRMSVLFALRVYADTVDNSQAILFTTCTAACINLFCIVIFNWIYNYVAEYLTEFELLRTQTEFDDSLTLKIYLLQFVNYYASIFYIA
FIKGKFIGSPDDYSKLF-GFRQEECGPGGCLMELCIQLAIIMIGKQAM-NTVLEMLFPLFYKWLNTVKVKTGLSKS---YKKSRPQWLKDYKLVEWRSLF
PEYLEMVLQYGFVTIFVAAFPLAPFFALLNNVLEMRLDARKLITFYRRPVSQRVKDIGVWYRILDSIGKLSVVTNGFIIAFTSEFIPRIIYTMYVSKDHS
LTGYLNFSLSYFNTSHFQNESAP-RN-Y--ASEAICRYPDFRQPPESSQRYQPTAIYWHILAARLAFVVVFENIVAFIIIIIKWCIPDIPGDLKDRIRRE
AYITNEIIIKQETIRAQNGYLYP-------------------------------------
>tr|U4UV79|U4UV79_DENPD Anoctamin OS=Dendroctonus ponderosae GN=D910_11423 PE=3 SV=1
----------------------------------------------TPEVQISRLPSPQRSVDFVLVWHTVESDS-------------------------
--------------------E-DASEKRRIFEKNLIDEGLDLEYENQ-ESSKLKFVKI----------------------PRQVHRTNFFVEGVSEQWAK
VKEWIFLDKDKFP-ENDQRFTAIYSRDREYLFDI-NSPCFFTSAIHSRIVQFILDRKRFSDNRFAFGMERLIDDNVYAAAYPLHDGD---------LRNL
LYTEWACLGKWYRYQPLDCIKEYFGVKIALYFAWLGYYTHILLAPAIVGLACFIYSLATMYSHKPSNDICDVGLEEKMCPHCDIWCDYWNIKETCVHSRI
TYLFDNSTTVFYAVFMSLWATTFLEMWKRYSAEITHRWDLTGFDVQE----EHPRPQYLARLAHVKRKCVNTNME--PHVC-------------------
--MALATVLAVVLYRMSILVSLKVHSDKMDNSSAILFTTVTAASINLVAILIFNQIYNYVAEYLTEFELLRTQTEFDDSLTLKIYLLQFVNYYASIFYIA
FFKGKFVGSPKRYNRVF-GYRQEECGPGGCLLELCIQLAVIMIGKQAM-NTVLEMLFPLFFKWLNTLKVMIENQNA---FQE--------------TTSP
AKDLDPVLQYGFVTIFVAAFPLAPFFALLNNILEMRLDAKKLLTMYRRPVSQRVRDIGVWYRILDSIGKLSVVTNGFIIAFTSDFIPRLVYQISINPNGS
LEGYVNNSLSYFNTSDFEAGRSGRTN-N--SIDTVCRYPDYRNPPWSSEKYERTALYWHILAARFIFVVVFENLVVLVMIILKWCIPDMPGKLRDRIRRE
AYITNEIIIKQETLRAQRAHSCS-------------------------------------
>tr|H9J1C7|H9J1C7_BOMMO Anoctamin OS=Bombyx mori PE=3 SV=1
----------------------------------------------INNNPSLTFNDGVRSIDYVLVWESGRNDAT------------------------
--------------------T-EAYEQRRIFEQNLEHDGLQLEREEPEGLYGLNFVKIHVPVDVLRDYSEILKLRMP-------VKTSNFIDRVEATWDK
FISKIRVDPELFP-ERRHRLTAIYSKDKEYLFDT-TSECFWTPSIRSRIVQFILDRKKFSK-PFAFGINRLISNCTYSAAYPLHDGD---------LRYL
LYTEWAAVSKCLKYQPLDYVKDYFGVKIGLYFAWLGFYTHMLIPASLVGLICFIYSAATVYSNKPSEDICNYNSTIKMCPQCDYFCEFWDLKATCLQSRI
TYLFDNSTTVFFAIFMSFWAACFLELWKRYSAEMTHRWDLTGFDVYE----EHPRPQYLARLAHVKRRQLNTGNE--PMVPFWRMRLPATLMSFSVVALL
VLLALATVLGVVLYRMSLLGAARHNDNVLITYSPIMFTTATAACINLCFIFLFNYIYQYLAEGLTEKELLRTQTEFDDSLTLKIYLLQFVNYYASIFYIA
FFKGKIIGRPGEYIRFF-GHRQEECAPGGCLLELSIQLAIIMVGKQFI-NTIVEMMMPYLLSWWNIIRTI-GRK----RQLKSPLQWVKDFKLVDFMGLF
PEYLEMILQYGFVTIFVAAFPLAPLFALINNVLEMRLDARKFLTCFRRPVPQRVTDIGVWYRILDSIGKLSVITNGFIIAFTSEFIPRLVYAF---THGS
LEQYVNNTLADFNITVLEHP-------P--LNSTFPGYWDYKN----GKDYAHSTWYWHIIGARLAFVVVFENVVALGTIIVKWAIPDMSGELRDRIRRE
AYVINSYILEETRARSQAGRDSQ-------------------------------------
>tr|A0A067QQS1|A0A067QQS1_ZOONE Anoctamin OS=Zootermopsis nevadensis GN=L798_14445 PE=3 SV=1
----------------------------------------------MILTSPSMFLDEGHSVDFVLVWTDSSEACN------------------------
--------------------K-DALKKREVFEHRLEEEGLILEREQ---NRSLHFIKIHAPVEVLGRYAEILKLRMP---DEDIEPSFDIMLEVKSMVRR
LVEFVLVNPTVFH-PQEHRLTAEFNREKIYLFDV-DSENFFTAAVRTTVVDFILERMQFSEDNFCFGVNRLISEGVYSAAYPLHDGD---------YRHS
LHKEWASIRKWIMYQPIDHIKEYFGIKFGLYFAWLGFYTHMLIPAAVVGLICFFYGLATMYSNTLSEDICNRRLNIVMCPLCD-TCRYWNLTDACDYARV
TYLFDNSSTVFFAFFMSFWGTLFLELWKRYSADITHHWGLSGFDLQA----EHPRPEYLARLRDAKYPKINTQEE--PYVPFWKVRVPATILSFSVVLLL
ITVAVGAVFGVVLYRMASVGPKS----IFEGQNKIILIPATAAVINLVCIMLLNYLYDWLAVKLTEMELLRTQTEFDDSLTLKIYLFQFVNYYTSIFYIA
FLKGKFVGYPAKYNRVF-GWRQEECNPGGCLMELCIQLAIIMVGKQAY-NTVLEMVIPLLFKWWNTFKIKTGLQAK--ENGKIKKQWTEDYKLLGWRGLF
PEYLEMVLQYGFVTIFVAAFPLAPFFALLNNVLEMRLDAKKFLRFYRRPVPKRVKDIGVWFCILDILGRISVVTNAFIIAFSSNFIPRIVYMMTVSQDHT
DVGFLNHSLAYFDTAHFSHSL----TNI--PHVDICRYPEYRNPPWHERPYKRPLIYWHILAARLAFVVVFQNVVSFVMMAVQWLIPDTSRHLRDKIRKE
AYLTNEIIIDQERKRAQAMNRGQ-------------------------------------
>tr|E0VLJ2|E0VLJ2_PEDHC Anoctamin OS=Pediculus humanus subsp. corporis GN=Phum_PHUM288550 PE=3 SV=1
----------------------------------------------SNERSSSFFKDGYRSIDYVLVWDKFQPRSL------------------------
--------------------D-INVEKRQIFEDNLRGEGLDLEYENE--VDGLNFIKIHAPLQVLRRYSEILKLRMP---PQGVDRTNSFFDKCNASIYS
VLKHIYVDKKIFP-RKSHRFTAVYSRDKEYLFDV-NSPGFFTPAIHSRIVQFILDRQRFSLDDFAFGIERLINENVYRAAYPLHDGD---------LRYT
LFNEWGSIKRFYRYQPLDYVKDYFGVKIALYFAWLGFYTHMLVPASIVGLVCFIYSCCTIYQNQPSQDICENQLKIKMCPLCDFFCDYWDLSETCLHARV
TYLIDNPSTVFFAIFMSFWAAMFLELWKRYSAEITHRWDLTGFDINE----EHPRPEYLARLAHVEKKHVNTNME--PYVPFWKVRFPATMLSFSIVLLL
VAMAVAAVLGVVLYRMSLLAALSVYGDSVITSYAILFTTATAATINLFCIFIFNWIYSWLAECLTELEFLRTQTEFDDSLTLKIYLLQFVNYYASIFYIA
FFKGKFIGYPGNYNRLF-GYRQEECGPGGCLMELCIQLAIIMVGKQAA-NTILEMLFPLFFKWLNLRWLRTELRGS---I-KGAWQWLKDFKLIQWRGLF
PEYLEMVLQYGFVTIFVAAFPLAPFFALINNVFEMRLDAKKLLTFYRRPVTQRVRDIGVWFKILNSIGRLAIITNGFIIAFTSEFIPRLVYVLHVNVNKS
LDGYLNHSLSYFDVTEFPKESAPQNT-V--YNISYCRYPDYRQGPWQEKPYSTTSTYWHVLAARLAFVVVFENAVVLVILLVQWCVPSIPGYLKDKIRRE
AFITSEIIIKQETERARRAGLTP-------------------------------------
>tr|A0A0R1E0M9|A0A0R1E0M9_DROYA Uncharacterized protein, isoform B OS=Drosophila yakuba GN=Dyak\GE25120 PE=4 SV=1
----------------------------------------------GEINSSLFFEDCIRSIDFVLAYRINSHEPT------------------------
--------------------E-ENTEKRRVFEANLISQGLEVEASQ---KDQIWFVKIHAPLEVLRRYAEILKLRMPL-IPSVVRSTKSVFSSLKHVFQF
FLRNIYVDEEIFP-KRAHRFTAIYSRDKEYLFDI-RQDCFFTTAVRSRIVEFILDRQRFPAKNMAFGIERLIAEGVYSAAYPLHDGE---------IRAL
LYKHWASVPKWYRYQPLDDIKEYFGVKIGLYFAWLGYYTYMLLLASIVGVICFLYSWFSLKNYVPVKDICQSNTNITMCPLCD-WCNFWDLKETCNYAKV
TYLIDNPSTVFFAVFMSFWATLFLELWKRYSAEITHRWDLTGFDVHE----EHPRPQYLARLEHIPPTRVDTNKE--PTVPFWRMKLPATVFSFSVVLLL
IALAFVALLAVVVYRMSMLAALKVGASPMTTSSAIVLATASAAFVNLCLLYILNYMYNHLAEYLTELEMWRTQTQFDDSLTLKIYLLQFVNYYASIFYIA
FFKGKFVGHPGEYNKLF-DYRQEECSSGGCLTELCIQLAIIMVGKQAF-NTILEVYLPMFWR--KVLAVQVGLSRNINPDKTKDERWMRDFKLLDWRGLF
PEYLEMVLQYGFVTIFVAAFPLAPFFALLNNILEMRLDAKKLLTHHKRPVSQRVRDIGVWYRILDCIGKLSVITNGFIIAFTSDMIPRLVYRHYVNKNGT
LDGYLNFTLSEFKVADSPTLYSLA-GDL--SNITTCRYTDFRLPPSSPEKYTLSSMFYIILACRLGFVVVFENFVALVMILVRWCIPDMSVELRDQIRRE
VYVTNEIIIEQEAHRARFERAKR-------------------------------------
>tr|Q175J3|Q175J3_AEDAE Anoctamin OS=Aedes aegypti GN=AAEL006656 PE=3 SV=1
----------------------------------------------PSVNNSLYFADGVKSVDFVLVWKTSLEEEI------------------------
-------------------HLEIREKKRFIFEQNLIRDGLELERELI--ENEIHFIKIHAPLEVLRRYSEILKLRMP---PAGVSRTTSILSRLKGFAGK
IVHYFLVEEKYFP-PRSHRFTAVYSRDKEYLFDL-KQACFFTAAVRSRIVQFILDRKRFSEDSYAFGIERLITEEVYIAAYPLHDGE---------IRHL
LYTKWAAVSKWYRYQPLDYIKEYFGVKIGLYFAWLGYYTYMLLLASIVGILCFIYSWKTLRYNTPSEEICSKENNIMMCPLCDHWCDYWELSETCLHARA
TYLFDNPTTVLFAIFMSFWATLFLELWKRYSAEITHRWDLTGFDVHE----EHPRPQYLARLAHVRRKKINTNEE--PQVPYWRMKLPATILSFSVVLLL
VCLAIVAVLAVVLYRMSVLATLSVYGDEVTTSVAILFTTATAATINLCLIVVFNWMYTYLAEWLTERELLRTQTEFDDSLTLKIYLLQFVNYYASIFYIA
FFKGKFIGYPGNYNRFF-NFRQEECGFGGCLMELCIQLGIIMIGKQAV-NTVLEMAIPIFYKWLNSLKVRIGKQRS---LKSKGQRFVKDLKLVEWRGLF
PEYLEMVLQYGFVTIFVAAFPLAPFFALMNNILEMRLDAKKLLTFYRRPVSQRVRDIGIWYRILDSIGKLSVITNGFIIAFTSDFIPKLIYRLNISSDGS
LNGYLNYTLAYFNTSDFQKGSEPFQS-Q--YNVTVCRYPDFREPPGSSNPYEKTTMYWLIMAARLAFVVIFENIVAIVMILVRWCIPDMSQDLRDQIRRE
AYITNEIIIKQETLRARMDRESE-------------------------------------
>tr|A0A0A1WMC3|A0A0A1WMC3_BACCU Anoctamin OS=Bactrocera cucurbitae GN=Ano1_3 PE=3 SV=1
----------------------------------------------WKFRTRRRFQDGKRSVDFVLAYIGDDDY--------------------------
---------------------IENRRKREIFETNLIKEGLHLEHDN---TQRIHFIKIHAPLEVLCRYAEILKIKLPMKIPELIEDDFRIKDCLTTACSR
FFSWLKVSPE-----RPYRIHFEFSRNYEHLFDW-EQPNFFDAGVRNSIINFILERQNFVEGEDNLGIEKLLEDRVYHSAYPLHDDT---------DRDF
LLQEWATLRKWIHLQPLDSIKEYFGAKVALYFAWLGFYTHMLIPVSVLGILCFVYGFVTWNSDPISRQICNDNQTTLMCPQCDRNCDYWLLEKTCNSSKM
NYLIDNNITVVFASIMALWAVFYLELWKRYSATLVHRWGLTTFSQHV----EHPRPQYLSKLQKHKDTERWHNLE--PDVPFWRIKFLPSFTSYSIMVLF
ICVSLIAIFSMIVYRMAQKASHSILGSDNSMTYKIMVLPMTAGIIDLIVISMLDYVYTSLAVYLTNMEYCRTQTEYDESLTVKNYIFQFVNYYSSLFYIA
FLKGKFVGYPAKYNRIL-GFRQEECNPGGCLMELCMQLVIIMVGKQAV-NAIVEMFFPYIMRFIRKLSARMGMRK--EEKLISCNQWTEDYHLEPSNSLF
SEYLEMVLQFGFITLFGLAFPLAPLLALINNVIEVRLDAIKMLKLIRRPVAQRASNIGVWYNMMAIVARIAVASSAMIIAFSTNLIPKLVYTTA-TNDAS
LEGYLNFTLAYFNTEDFQVQPVLHGSIY--ENATSCRYTEFRNAPWDDNPYKRPTYYWKILTGRLAFIVVFQNVIGVIQGIIAWAIADEPSKLRKRIKRE
GFLLREHIIEYEKKTAAEKAAAR-------------------------------------
>tr|A0A0L0C4Q6|A0A0L0C4Q6_LUCCU Anoctamin OS=Lucilia cuprina GN=FF38_03303 PE=3 SV=1
----------------------------------------------WKFRTRRRFQDGQRSVDFVLAFSGADHK--------------------------
---------------------LDNIKKREIFEANLEKEGLHLERDN---TQRIHFIKIHAPHEVLCRYAEILRIKLPMKIPDQIAEEFELSESVRSCCAK
IFKSVQLNPEKFP-PKPKRIYFEFQRNYEHF---------------------------------------------------------------------
-------------LQPLDSIKEYFGAKVALYFAWLGFYTHMLIPVSIIGILFFIYGFVTWNSDPISREICNDNNATLMCPQCDRNCDYWQLKATCNSSKI
NYLIDNNITVVFAFVMSIWAVLYLELWKRYSARLVHRWGLTGYTHDV----EHPRPQYLAKLRKNKKADKLNSFE--PDVPFWTTKFLPSFTSYSIMVLF
ICISIIGIFSMVVYRMAQRASHSIFGNEDSMTYKIMFLPMTAGVIDLILISILDYIYGSLAVTLTNWEYCRTKSEYDESLTIKNYVFQFVNYYSSLFYIA
FLKGKFVGYPAKYNRIL-GFRQEECNPGGCLMELCMQLVIIMVGKQAV-NAIVEMLIPYLTKTFKKFGTRCGMRK--EEKLVSCNQWTEDYHLIPWHSMF
LEYLEMVLQYGFITLFGLAFPLAPLLALINNIIEVRLDAIKMLKFIRRPVAERAHDIGVWFSIMTVVTKIAVASCAMIIAFSTNLIPKLVYKTA-THDET
LEGYLNFTLAYFNTKDFQIQPLIVGSPY--TNVTSCRYTEFRNPPWDENPYKRPMIYWKILTARLAFIVVFQNIIGVLQTIIAWAIPDVSGKLLKRIKRE
NFLLREHIIEYEKIMAQKA-AAK-------------------------------------
>tr|R7TUE0|R7TUE0_CAPTE Anoctamin OS=Capitella teleta GN=CAPTEDRAFT_222303 PE=3 SV=1
------------------------------------------------RGRNIFFDDGIRRIDYVLAYPSKYKDSSEQ----------------------
---------------------ENQEKKRLVFERNLEEEGLELEHDIV-DGREIQYTKVHAPWEVLVRYAEIMKTRMPIKVPDEIRSQS-MWEIMADYMSA
LLSPFQLDPAVVP-PVPKKFTHVFERDKSYLFAIERKEMFFSHAARSRITDYILRRKKYSDEESSFGIKRLISMQTYSAAYPLHEVTFFSSWTRPSMRRL
LYENWAHWRNWFKVQPLDYIRVYYGEKTGLYFAWLGYYTYMLIPASILGLAVFIYGVVTIDDSVVAKESCDWSNNFTMCPLCNKRCPYWNYAAVCTDVYA
SHMFDNALTVAFSMFMGLWGTVFLEFWKREQAAIQFKWNLLNFQEEE----EPPRPEYLIRLSTSKFKKKHKIMEP--FLPFWRRRVPVFAASASVMLLM
CLAAVGVVIGIIVYRMSTLSALYLQDEELLYKNAGIVASTTAACINLVAIFILNFAYSKLAEILTDWECLRTQSEYDSSLSFKLYVLQFVNYYSSIFYIA
FFKGRFAGRPGNYNTFF-GARQEECQ-GGCLMELCIQLAIIFVGKQLLQNNLMEIFLPRVKRWIKEKCCSGED----KVDKSRLRPWEKDLSLNEMQGLF
YEYLEILIQFGFVTLFVAAFPLAPFCALLNNIIEIRADADKFVTQYRRPMAQRSKDIGIWYEVCYVVSRLAILTNAFLITSTSSFIERLVYEMEYSDSGG
LEGFVNSSLAYFNVSDFDQIEVPDDPNGEYLNITLCRYKGYNEPPWANDPYAYTTQYWHIMAAQFIFVVVFENVIIVLTSLLAYMIPDMPRKLTEQVHRE
AYLTNEIILKTELEIAKGQQPDLS------------------------------------
>tr|A0A0P5IEU7|A0A0P5IEU7_9CRUS Anoctamin-5 OS=Daphnia magna PE=4 SV=1
------------------------------------------------HNSTTFFDDGVRKIDFVLVWDELLPS-NVS----------------------
---------------------EISDCKREVFESNLEKEGLQIEYVDT-PGVSLHFIKLHAPDEVLRRYAEILKLRMPMKIEQDVINCVGMVHEVKSRFDS
ILDYFRPDPHLFP-VKAQRFSAVYSRDKEYLFNVD--EDFFTSSIRSRIVDFILKRKRFKEDTDAFGIERLLTEGVYSAAYPLHDGSDH---VDGNLRSL
LRTEWTALNKLHRYQPLDYVKDYFGVKIALYFAWLGFYTHTLLFASVVGFFCFLFSFLSLPSNIPSNDICSGRFNVVMCPICDNSCDYWYIFETCLHSRA
AYLFDNGTTVFFAVFMSFWAVLFLEMWKRYSAEITHRWDLTGFDHQE----EHPRPQYLARLTHVKAKRVNVVLEP--RVPFWRIKVPAALLSISLILLL
VSMAMASVMGVILYRMSLLASLSIHNDQNITANAMLITTATAAFINLCCILLFNRFYEKIALWLTEQELPRTQSEFEDSLTLKMYLLQFVNHYASIFYIA
FFKGKFIGYPGDYNRFF-GYRQEECGTGGCLVELCIQLAIIMVGKQAMN-TCMEMVLPMVFKWFNSIRVRKQP----KESQAYKAQWAKDYQLVAWEALF
AEYLEMVLQYGFVTIFVAAFPLAPLFALLNNVLEMRLDARKILTLHRRPVAQRVKDIGVWYTILDCLGKLSVATNGLIIAFTSDFIPRLIYTLKYSPDHS
LSGYVNYTLAYFSTSDFSHAQQVSN---ASAAVDICRYRDLRETPWLPNKYALSADFWYILAARLTFVLVFQNFVALVTMVIRWIIPDVPRKLSERIRQE
AYFTNEIIIKQEMIRARGSVRGAQ------------------------------------
>tr|E2AZ67|E2AZ67_CAMFO Anoctamin OS=Camponotus floridanus GN=EAG_05077 PE=3 SV=1
-----------------------------------------------IDSETLYFRDGHRRIDMVLVYQEENEG--------------------------
---------------VMTEIEARRREHRRVFQQNLLKEGLQLELEPKEFDGKTYFLKLHIPWKIKVQYAEVMSLKLPTKFTWDTDGAKKFMERWRRWVQW
ARKIHTWDTTK-YPEEPNFYDYIDSGDLEERFIVKERDNAYTPAQRSLIVMQILLRTRYDENHEKSGIRRLLADGTYLDCFSLHEGPYNKPNGEILDRYL
LYLIWARPSQWYKKQPLWLIRRYFGEKVALYFAWLGFYTKCLYPPAVVGLLCFFYGLGSMEDNVPSKEICDSNGNITLCPLCDKACTYQKLGDSCIFSKL
TYLFDNPATVFFAIFMSFWATTFLELWKRRQAVIVWEWDLQNADY-D----EEPRPEFEASVKTFRINPVTKERE--PYLPAWS-KAVRFLATGSIVFFM
ICVVLGAVLGTIVYRISLVAVFYGGGGSFLKRHAKIFTSMTAALINLVIIMILTRIYHRLARWMVNMENPRTQTEYEASYTFKIFLFEFVNFYSSLIYIA
FFKGRFFVHPGDADARFYRIKTDVCDPAGCLSEVCIQLAIIMVGKQCF-NNFVEILSPKLWNWWRKRTQVAAT----KNHDRRYTCWEKDYQLQDPLALF
EEYLEMILQYGFVTLFVAAFPLAPLFALLNNIAEIRLDAYKMVKEARRPLAERVEDIGAWFGILRGVTYVAVVSNAFVIAYTSDFIPRSVYAFVYSPTED
LVGYIDSSLSEFNTSDYREDMKSDVED---EHPETCQYRGYRNGPEDNEPYGLSPQYWHVFAARLAFVVVFEHVVFALTGIMSYVIPAVPHSLSTQLRRE
RLIAQEEKYEKEIKG---------------------------------------------
>tr|A0A0L7R9Y8|A0A0L7R9Y8_9HYME Anoctamin (Fragment) OS=Habropoda laboriosa GN=WH47_11435 PE=3 SV=1
-----------------------------------------------LDPETLYFRDGRRRIDMVLVYREDNNG--------------------------
---------------VMTEIEARRKEQRRVFQQNLLKEGLQLELEPKEFDGKTYFLKLHIPWKIKVQYAEVMNLKLPTKFTWQ-EDAKKLWEKWMRWIKW
IKKIHTWDIKK-YPEEPSFYDSIDSGDREERFVVKDRDTAYTPAQRSLIVMQILLRTRYDENHEKAGIRRLLADGTYLDCFSLHEGPYNKPNGEIFDRHL
LYLIWARPSQWYKKQPLWLIRRYFGEKVALYFAWLGFYTKCLYPPAIVGFLCFMYGVGSMEDNIPSKEICDDGGNITLCPLCDKACSYQRLGDSCLFSKL
TYLFDNPATVFFAIFMSFWATTFLELWKRRQAVIIWEWDLQNVES-D----EEPRPEFETTVKTFRINPVTRERE--PYLPAWS-KALRFCATGSIVFFM
ICVVLGAVLGTIMYRISLVPVFYSGGGTFLKNHAKIFTSITAALANLVIIMILTRVYHRLARWMVNMENPRTQTEYESSFTFKIFLFEFVNFYSSLIYIA
FFKGRFFVHPGDTDARFFRIKTDVCDPAGCLSEVCIQLAIIMVGKQCF-NNFVEILSPKLWNWWRKRNHVAAT----KDHARPYTYWEKDYQLQDPLALF
DEYLEMILQYGFVTLFVAAFPLAPLFALLNNIAEIRLDAYKMVKEARRPLAERVQDIGAWYGILRGVTYVAVVSNAFVIAYTSDFIPRSVYAIVYSPTKD
LVGYIDSSLSDFNTSDYRDDMKSDMDR---NHPETCQYRGYRNGPDHTDPYGLSPQYWHVFAARLAFVVVFEHIVFALTGIMSYVIPAVPHSLSTQLQRE
SLLAQEAKYEKGLKS---------------------------------------------
>tr|K7J4Y8|K7J4Y8_NASVI Anoctamin OS=Nasonia vitripennis GN=LOC100121414 PE=3 SV=1
-----------------------------------------------FEYDTLFFRDGRRRIDMVLVYRDDTGG--------------------------
---------------VMTEQEARNREQRRVFEQNLLKEGLQMELEPAEFDGRTNFLKLHIPWKVKVQYAEVMNIKLPCKFTWD-ENAKKSWKRWMRCLNW
VRSIHLWDTSK-YPEEPSFYESADPGDREERFVVKDRDTAFTPAQRSLIVMQILLRARYDEVHEKAGIRRLLADGAYVDCFSLHEGVYNKPNGQILDRYL
LYLIWARPGQWYKKQPLWLIRRYFGEKVALYFGWLGFYTRALYPPAIVGLLCFFYGLGSMEDNVPSKEICDSKGNITICPLCDKACPYTKLGDSCLFARL
TYLFDNPSTVFFAIFMSFWATTFLEMWKRRQAVLAWEWDLQDGEG-D----EEPRPEFEASVKTFRINPVTRERE--PYLPVWS-RTLRYVATGSIVFFM
ICVVLGAVLGTIIYRISLVAVFH-GGGYFLKRHAKIFTSLTAAFINLIIIMILTRIYQKLARWMVNMENPRTQTEYEASFTFKIFLFEFVNFYSSLIYIA
FFKGRFYVHPGDAESRFYRIRTDVCDASGCLSEVCIQLAIIMIGKQVF-NNFVEILSPKLWNWWRKRTHVAAT----KDQSRPYTSWEQDYQLQDPLALF
DEYLEMIIQYGFVTLFVAAFPLAPLFALLNNIAEIRLDAYKMVKEARRPLAERVEDIGAWYGILKGVTYAAVVSNAFVIAYTSDFIPRTVYAFVYSPTDD
LVGYIDSSLSEFNTSHYTADMRSEEDQQ--RAPPTCQYRGYRNGPDHEDPYGLSPQYWHVFAARLAFVVVFEHIVFALTGIMSYIIPEVPRSVATQRQRE
RLLAQEAKYEKGVKG---------------------------------------------
>tr|Q0IEX5|Q0IEX5_AEDAE Anoctamin OS=Aedes aegypti GN=AAEL007716 PE=3 SV=1
-----------------------------------------------LDPESLMFRDGRRKIDMILCYEEEDEG--------------------------
---------------VMTEIEALKRHQRKIFQESLVKEGLEIEIEHKSFDEKTYFIKVHIPWRTESRYAEVMNLKLPVKFTEELRKHQKWLAYW----NK
LMSVTEYNYSR-IEKEPSFYSATANGNPEEQFIVKDRCTTYNSAQRSLIVMQILMRTRFDETEKNVGIKRLLNDGTYLACFPLHEGRYERNSGAIFDRRL
LYLEWARPAKWYKKQPLCLIRKYFGDKIALYFCWLGFYTKMLYAPAIVGFFCFLYGLASMDDNIPTKEICDENGNITLCPLCDRACSYQQLSESCLFAQL
TYLFDNPSTVFFAIFMSFWATTFLEMWKRKQSVLIWEWDLQNIEN-E----EDTRPEFETSVKTFRTNPVTREKE--PYMPTWD-RAIRFFATSSAVLFM
IAVVLGAVLGTIIYRISLVSVIYSGGGRFFRKHAKLFTTMTAALINLIIIMILTRIYHKLAIYLTNLENPRTQTEYEDSYTIKIFVFEFMNFYSSLIYIA
FFKGRFFDYPGDDVARFFRLKGDICDPAGCLSELCIQLAIIMVGKQCW-NNLMEYFFPAFYNWWRQRKHKQLT----KDETHLHMAWEQDYHLQDPLALF
DEYLEMIVQYGFVTLFVAAFPLAPLFALLNNIAEIRLDAYKMVTQSRRPLAERVEDIGAWYAILKIITYTAVVSNAFVIAYTSDFIPRMVYKYVYSPQFT
LHGYIEHSLSVFNTSDYKDEWGTKT--E--SDPDICQYRGYRNGPTDEEQYGLSPHYWHVFAARLAFVVVFEHIVFVLTGIMQFIIPDIPVEVKTQMQRE
QMLAKEAKYQHGLKK---------------------------------------------
>tr|A0A0K8SA97|A0A0K8SA97_LYGHE Anoctamin OS=Lygus hesperus PE=3 SV=1
-----------------------------------------------PDRDSLFFEDGKRRIDLVMVYEEDSVG--------------------------
---------------PLPELEHMRTETRREFHRNLQKLGLELELEDKKFDQKTYFLKVHVPWKLLTRYAEIMNLKMPIKFSWEDKQQEEPYPFL----FP
LLKIFDLDTKL-IDEEPSFYTATFSRDREEQFIVKDRETFFTSAQRSQIAWTILMRTKFDEDQKNVGIRRLLNNGTYLSAFPLHEGSYDRDNGVRFDRRL
LYLEWARPGRWYKKQPLWLVRKYFGDKIALYFAWLGFYTEMLIPAAIVGLLCFFYGLLSMEDNIPSREICDGSGNITLCPMCDKVCRYQKLSESCLFSRI
TYLFDNPATVFFAIFMSFWATTFLELWKRRQAVIAWEWDLSYTEE-D----EEPRPEFEATVKTFRVNPVTRQKE--PYMPPSQ-RAWRYTITVSTVLFM
ICIVCAAVLGTIVYRLSVVNYIYLSSNTFIKRHAKIFTSITGATINLITIMILTRLYGEIAIWLTNQENPRTQIEYEDSFTFKIYFFEFMNFYSSLIYIA
FFKGRFFSYPGDQDSRLARIKGDVCDPAGCLFELCIQLAIIMVGKQLF-NNFLELAYPAMINWWRKRIHKSQT----KDKSRAYTRWEQDYQLQDPLALF
EEYLEMVLQYGFVTLFVAAFPLAPFFALVNNIGEIRLDAFKMVAQSRRPLAERVEDIGAWYGILQGVTYCAVVSNAFVIAYTSDYIPRMVYKLVYSKTND
LVGYIDSSLSAFNTSDYLDEMGVDKDEG--DDPEICQYRGYRNGPEDKEKYGLSPQYWHVFAARLAFVVVFEHIVFALTGIMAYTIPDVPSEIRTQIQRE
RMLQKEAQFERGVNV---------------------------------------------
>tr|A0A022T590|A0A022T590_9HYME Anoctamin OS=Microplitis demolitor GN=K425_602 PE=3 SV=1
-----------------------------------------------PDPETLFFRDGRRRIDMVLVYQEETEG--------------------------
---------------VITEIEAKKREQRRVFQENLLKEGLQMELEPKEFDGKTFFLKLHIPWKIKIQYAEVMNLKLITKLTWG-DGKKKFWEKMGNCLNL
FKRIHSWDTKL-YPEEPSFYTGQDSDSREERFLVKDRESSYTPAQRSLIVMQILSRTRYDDVHEKAGIKRIIADGTYLDCFCLHEGPYDSPDGVPLDRHL
LYLIWARPSQWYKKQPLWLIRRYFGEKVALYFAWLGFYTRALYLPAIVGLLCFIYGLLSMQDNVPSNEICDPNGNITLCPLCDRACAYRRLGDSS-----
--------------------TSFLELWKRRQAVIVWEWDLQNADG-D----EDPRPEFETTVKTFRINPVTRERE--PYMPLLS-RVWKNMVTGSLVFFM
ICVVLGAVLGTIIYRVSLVAVFYGGGDSFISKHAKIFSSTTAAVLNLIMIMLLTRVYQRLAKWMVNMENPRTQTEYEDSFTFKIFIFEFVNFYSSLIYIA
FFKGRFYVHPGDADARFFRIKTDVCDPAGCLSELCIQLAIIMIGKQLF-NNFMEILSPKLVNWWRKRTHVART----KDHERPYTSWEQDYQLQDPLALF
DEYLEMIIQYGFVTLFVAAFPLAPLFALLNNIGEIRLDAYKMVKEARRPLAERVEDIGAWYGILKGLTYAAVVSNAFVIAYTSDFIPRCVYAFVYSPTND
LVGYIDSSLSEFNTSDFREDMINPSIT---SPPPKCQYRGYRNGPDHTDPYGLSPQYWHVFAARLAFVVVFEHFVFSLTGVMSYIIPETPSAVTTQLSRE
RLLAQEAKYEKGVKG---------------------------------------------
>tr|A0A0C9REX8|A0A0C9REX8_9HYME Anoctamin OS=Fopius arisanus GN=Ano5_3 PE=3 SV=1
-----------------------------------------------TDHETLFFRDGRRRIDMVLVYQEETEG--------------------------
---------------VMTEIESKRREQRRIFQENLLKEGLQMELEPKEFDGKTFFLKIHIPWKIKVQYAEVMNLKLLTKFTWG-DATKKFWEKWSNFLSF
LQRFHMWDTSL-YPEEPNFYATHDSGDREERFLVKDRETAYTPAQRSLIVYQILMRARYDETHEKAGIRRLIADGTYIDCFCLHEGPYNRPDGVPLDRHL
LYLIWARPSQWYKKQPLWLIRRYFGEKVALYYAWLGFYTRSLYLPAIVGLLCFVYGLSTMEDNIPSKEICDPEGNITLCPLCDKACDYRKLKESCLFSRL
TYLFDNPATVFFAIFMSFWATSFLELWKRRQAVIVWEWDLQNVDG-D----EEPRPEFETSVKTFRINPVTRERE--PYMPAYS-RAWRYCVTGSLVFFM
ICVVLGAVLGTIIYRISLVAVVHSGGGSLLQRHAKIFTSMTAALINLIIIMILTRIYQKLAKWMVNMENPRTQTEYEDSFTFKIFFFEFVNFYSSLIYIA
FFKGRFYVHPGDADARFFRIKTDVCDPAGCLSELCIQLAIIMVGKQCF-NNFMEILSPKMVNWWRKRTHVAAT----KDHERPYTYWEQDYQLQDPLALF
DEYLEMILQYGFVTLFVAAFPLAPLFALLNNIGEIRLDAYKMVKEARRPLAERVEDIGAWYGILKGVTYAAVVSNAFVIAYTSDFIPRSVYAYVYSKTND
LQGYIDSSLSDFNTSHYSEDMIGN---R--NGPPICQYRGYRNGPAHSDPYGLSPQYWHVFASRLAFVVCFEHMVFALTGLMSYVIPETPSAVSTQLSRE
KLLAQEAKYEKGVKG---------------------------------------------
>tr|E2A0E0|E2A0E0_CAMFO Anoctamin OS=Camponotus floridanus GN=EAG_04381 PE=3 SV=1
-----------------------------------------------GTKYSLYFCDEIRSIDFILVWDEYNGEA--QT---------------------
---------------------YRNVERRRIFEINLEKEGLQLEYEQV-ETNGLHFIKIHAPKTVLRRYAEILKLRLPMKLSSYQTSNI------------
--------------------------------------------------------------------------------PIIQEGDLR---TADSMRYL
LYKEWASLRKCLHYQPLDYIKEYFGVKIGLYFAWLGFYTHMLIPASIVGLLCFIYSCATLYYNKPSEDICNYNGTIEMCPLCDHFCGYWDLKETCLHARI
TYLFDNPSTVFFSIFMSLWATLFLELWKNYSAEITHRWDLTGLDAQE----EYPRPQYLARLAHIKKRSINTNTE-EPKVPYWKMRFPATILSFSVVLLL
IAVAMAAVLGVVLYRMSVLTALSVYGNPMVTSYAILFTTATAASINLCCIILFNWLYVWLAEYLTELELLRTQSEFDDSLTLKIYLLEFVNYYASIFYIA
FFKGKFIGYPGNYNRFFN-FRQEECGPGGCLLELCIQLSIIMIGKQTV-NTILEMLFPLFYKWMNTLKVHVGAKDNMRYSSRKNLQWIRDYKLVEWRSLF
PEYLEMVLQYGFVTIFVAAFPLAPFFALLNNVFEMRLDAKKLIIMYRRPVGQRVRDIGIWYRILDSISKLSVITNAFIIAFTSNFIPRLVYLITVSDNYS
LEGFLEHSLSKFNTSDLKSDT---QPKNQ-TSVEICRYPDYRESSDSPNKYDYSIIFWHILAARLAFIVVFENVVAFVMILVRWCIPDMSPKLRDKIRRE
AYITNEIVIHQEALRALERPETD-------------------------------------
>tr|A0A026W5Q0|A0A026W5Q0_CERBI Anoctamin OS=Cerapachys biroi GN=X777_09671 PE=3 SV=1
-----------------------------------------------GTKYSLYFVDEIRSVDFVLVWDEYNGEA--QT---------------------
---------------------YHNVEHRKVFEKNLEKEGLELEYEQV-EPNGLHFIKIHAPREVLRRYAEILKLRLPMKLLCQMSSSNIIIKEVNTFIRR
IMGKYYLDKTIF-PTMKQNFTAVYSRDKEYLFDL-DMPNFFTSATRSRIVQFILDRARFTETKEDFGIERLISDRAYVAAYPLHDGNLH---TADSMRYL
LYTEWASLRKCLHYQPLDYIKEYFGIKIGLYFAWLGFYTHMLIPASIVGLLCFIYSCATLYYNEPSEDICNGNGTIEMCPLCDYFCGYWDLKETCLHARI
TYLFDNPSTVFFSIFMSLWATLFLELWKKYSAEITHRWDLTHLDTQE----EYPRPQYLARLAHIKKKSINTNTE-EPKVPYWKMRVPATILSFSVVLLL
IVVAMAAVLGVVLYRMSVLTALSVYGHPMVTSYAILFTTATAASINLCCIILFNWLYVWLAEYLTEIELLRTQTEFDDSLTLKIYLLEFVNYYASIFYIA
FFKGKFVGYPGEYNRFFG-FRQEECGPGGCLLELCIQLSIIMIGKQAM-NTILEMLFPLFYKWMNTLKVHVGMKDDKRYSSRKHLQWIRDYKLVQWRSLF
PEYLEMVLQYGFVTIFVAAFPLAPFFALLNNVFEMRLDAKKLLTMYRRPVGQRVRDIGIWYRILDSISKLSVITNAFIIAFTSNFIPRLVYRITLSDNYS
LEGFLEHSLARFNTSDLKNGTQPMTSLGQ-SPVEVCRYPDYREPPDSPHKYEYTTMFWHILAAKLAFIVVFENIVALVMILVRWCIPDMSPKLRDTIRRE
AYITNEIVIHQEALRACERPEING------------------------------------
>tr|W4WJV1|W4WJV1_ATTCE Anoctamin OS=Atta cephalotes PE=3 SV=1
-----------------------------------------------GTRYSLYFRDEIRSVDFVLVWDEYNGEA--QT---------------------
---------------------YRSVERRRIFEKNLEKEGLQLEYEQV-ESNGLHFIKIHAPKEVLRRYAEILKLRLPMRLPCHMTSSNIIIEEVNSLFRR
VMNKYYVDTTIF-PTMRQNFTAVYSRDKDYLFDL-DSPNFFTSATRSRIVQFILDRTRFTETKEDFGVERLISEHTYVAAYPLHDGNLH---TPDSMRYL
LYTEWASLRKCLHYQPLDYIKEYFGVKIGLYFAWLGFYTHMLIPASIVGLLCFIYSCATLYHNEPSEDVCIGNNTIAMCPLCDHFCDFWNLKQTCLHSRI
TYLFDNPSTVFFSIFMSLWATLFLELWKKYSAEITHRWDLTGLDAQE----EYPRPQYLARLAHIKKKSVNINVE-EPQVPYWKMRLPATILSFSVVLLL
IIVAMAAVLGVVLYRMSVLTALSVSGHPMVTSYAILFTTATAACINLCCIILFNWLYVWLAEYLTEIELLRTQTEFDDSLTLKIYLLEFVNYYASIFYIA
FFKGKFTGYPGNYNRFFG-SRQEECGPGGCLLELCIQLSIIMIGKQAM-NTILEMLFPLFYKWLNTLKVHVGSKDNKRYSSRKYLQWVRDYKLVQWRSLF
PEYLEMVLQYGFVTIFVAAFPLAPFFALLNNVFETRLDAKKLLTMYRRPVGQRVRDIGIWYRILDSISKLSVITNAFIIAFTSNFIPRLVYRITVSDNYS
LEGFLDHSLAKFNTSDLGGTQ-PNMTLNQ-VPIEICRYPDYREPPNSSNKYKYNIMFWHILAARLAFIVVFENVVALVMILIRWCIPDMSCKLRNRIRRE
AYITNEIIIHQEALRACERSDTDG------------------------------------
>tr|H9JNR6|H9JNR6_BOMMO Anoctamin OS=Bombyx mori PE=3 SV=1
----------------------------------------------GLEPESLMFRDGRRRIDMVLAYEEEDYG--------------------------
---------------VMTEAEAKKRDYRRTFHENLIKEGLELELENKCFDEKTWFLKIHIPWKTEMRLAEVIGMKLPTKRFWSDKQVE-RDKRWYSKWRR
IWKIYEYEHSRI-EPEPSFYAATECVRREEQFLVKDRHTQFSPAQRSLLVMQILLRVRYDNTETKMGIRRLLNDGTYLGCFPLHEGRYDTDDGTVTDRRL
LYLEWARPSKWFKKQPLWLVRRYFGDKIGLYFCWLGFYTKMLYAPAIVGTLCFLYGLASMEDNIPSQEICDLKGNTTLCPLCDKACKYQTLADSCLFAKL
TYLFDNPATVFFAIFMSFWATTFLELWKRKQSVLRWEWDLGGVDY-D----EDPRPEFETSAKTFRTNPVTREKE--PYLPVWQ-KTMRYIATSSAVLFM
VAIVMGAVLGTIIYRISMVSVIYGGSGFFIQRHAKIFTAMTAALINLIIIMILTRIYAKVAVYLTNMENPRTQTEYEDSYTFKIFFFEFMNFYSSLIYIA
FFKGRFYDYPGDDQAEFFKLKGDICDPAGCLSELCIQLAIIMIGKQFF-NNFLELGFPKFHNWWRRRSHRAVT----RDPSKPHMAWEQDYHLQDPLALF
DEYLEMILQYGFVTLFVAAFPLAPLFALLNNIAEIRLDAYKMVTQARRPLAERVEDIGAWYGILRGITYAAVVSNAFVIAYTSDFIPRMVYKYVYSPDNT
LAGYIDHSLSLFNTSDYREDWGADENE---VDPPVCAYRGYRNPPDHADPYGLSPHYWHVFAARLAFVVVFEHVVFGLTGLMQLFIPDLPSELRIQMQRE
ALLAKEAKYEHGRRRLST------------------------------------------
>tr|N6U0P0|N6U0P0_DENPD Anoctamin (Fragment) OS=Dendroctonus ponderosae GN=YQE_08383 PE=3 SV=1
----------------------------------------------NPNPDSLFFRDGRRKIDMVLVYEEEELG--------------------------
---------------VMTEAEAKRRDNRKIFQENLVKEGLELELEHKNFDGKTWFLKIHLPWKTKTRYAALMGMKLPVKRFWDDKDQT-KGLSTWQTWVN
HWRLCEYNHELI-PKEPSFYDATEGRDREEQFVVKDRTTSYSNAQRSLIVMQILLRAKYDDTD-KVGIRRLLNNGTFLSVFPLHEGRWEQADGSVLHRRL
LYLEWANFGKMLKRQPLNLVRTYFGDKIGLYFCWLGFYTKMLISPAIVGTLCFMYGVLTMDDNTATHEICDPKGNITLCPLCDKACTYTKLVDSCKFAKL
TYLFDNPATVFFAIFMSLWATVFLELWRRKQSVIQWEWDLQGTEQ-D----EEPRPEFETSVKTFRTNPVTREKE--PYLPTSQ-KVFRMVITGSAVFFM
LFVVLAAVLGTIIYRLSLVTIIYGSQNLFLKNHAKIVTSVTAALINLIFIMSLTRGYHRLAIYLTNLESPRTTTEFEDSYTFKIFLFEFMNFYSSLIYIA
FFQGRFFDYPGDTISEFFRVKGDICDPAGCLSELCIQLAIIMIGKQML-NNFVEIFNPKFYNWWRYRSHRSNT----KDLSRKHTRWEEDYHLQDPLALF
DEYLEMILQYGFVTLFVAAFPLAPLCALINNVAEIRLDAYKMVTQARRPLAERVEDIGAWYGILKAITYAAVVSNAFVIAYTSDFIPRMVYKYKYSAEED
LVGYIDSSLSVFNTSDYHENMGPDDKA---QTPDVCQYRGYRNGPNESDAYGLSPQYWHVFAARLAFVVIFEHVVFALVGIMQYVIPDVPSELNTQIQRE
TLLAKEAKYEHGLRKTEY------------------------------------------
>tr|D2A4M0|D2A4M0_TRICA Anoctamin OS=Tribolium castaneum GN=GLEAN_15391 PE=3 SV=1
----------------------------------------------VLDPESLYFRDGRRKIDMVLVYEEEELG--------------------------
---------------VMTEAEARRRDHRRVFQENLVKEGLELELEHKDFDGKTWFLKIHLPWKTKTRYAAVMGMKLPIKRFWDDKNQN-KKETFWAKLQR
KFSFTQYNTDLI-PEEPSFYEATKGADREEQFVVKDRVTSYSSAQRSLIVMQILLRVKFDETD-KVGIRRLLNDNTYLACFPLHEGRWERNDGKILDRRK
LYLEWARPGKWMKKQPLCLVRKYFGDKIALYFCWLGFYTKMLIAPAIVGTLCFLYGLFTIDDNIPTKEICDPLGNITLCPLCDKACKYQKLIDSCKFARL
TYLFDNPATVFFAIFMSLWATVFLELWRRKQSVIQWEWDLNGTDQ-D----EEPRPEFETSVKTFRTNPVTREKE--PYLPASF-KVVRFFVTGSAVFFM
LAVVLCAVLGTIIYRLSLVSVIYGGGGTFLKRHAKIVTSVSAALINLIIIMCLTRFYHRLTIYLTNMENPRTQTEYEDSYTFKIFLFEFMNFYSSLIYIA
FFKGRFYAFPGDAAIIFSRVKGDICDPAGCLSELCIQLAIIMVGKQVF-NNFVELFNPKFYNWWRYRTHRSNT----KDLTRKHTRWEEDYHMQDPLALF
DEYLEMILQYGFVTLFVAAFPLAPLCALLNNVAEIRLDAYKMVTQARRPLAERSEDIGAWYGILRAITYTAVVSNAFVIAYTSDFIPRMVYQYKYSPTED
LVGYIDSSLSTFNTSDYHADMGGDNNEE--PPPSICQYRGYRNGPEDIDKYGLSPQYWHVFAARLAFVVIFEHIVFALTGIMQYVIPDVPSELKTQIQRE
TLLAKEAKYEHGLKKSDN------------------------------------------
>tr|A0A0F8ATW0|A0A0F8ATW0_LARCR Anoctamin OS=Larimichthys crocea GN=EH28_02466 PE=3 SV=1
-----------------------------------------------QSKDSVFFRDGLRRIDFVLSYVDDKD---------------------------
---------------------EKKQERRKVYEANLEKVGLQLEVEDKSEDGKTYFVKIHAPWEVLATYADVLKIKVPFKNDPDNTEM--PM-NW------
MSTPFRLPDIMHP--EPDFFTAPFNKSKSDFFLIDDRETFFPPSTRNRIVYYILSRCSYFRDKDKKGIKRLLNNGTYTSAFPLHDSRYWTRANCESERYN
LYKHWARFFCFFKEQPLNLVRKYYGEKIGIYFAWLGFYTEMLLFAAIVGTICFVYGVLTYDDNEWSKEICSEEGNIIMCPLCDKKCGYWKLNTTCNSSWQ
SHLFDNVGTVFFAIFMGIWVTLFLEFWKRRQARLEYEWDLVDFEEEQ--QQLQLRPEYETKCSNRKM-----N---------------R--------ITQ
ISLIIACIIGVIAYRLAVYAAFASIKSPTLQITPQLATSVTASCINFVIIMILNLMYERVAVWITDMEIPKTHLEYENKLTVKMFLFQFVNYYSSCFYVA
FFKGKFVGYPGKYAYMFGSERNEECDPGGCLIELTTQLVIVMTGKQVW-GNIQEALVPWLMNWWGSRKARSH-------PESLYSRWEQDHDLQGFLGLF
YEYLEMVIQFGFITLFVASFPLAPLMALINNIIEVRVDAWKLTTQFRRPVAAKAHSIGAWQEILNGMAVLSVVTNAFIVAFTSDMIPRLVYMYAYQPDGQ
MKGYINNSLSVFNISAFPLDNKPDDDENPFSIHTTCRYRDYRYPPGHEMQYKHTMQFWHILAAKLAFIIIMEHVVFFVKFFVAWMIPDVPSDVRARVKRE
RYLVQEYLHNYEVEKLKIQ-----------------------------------------
>tr|A0A034VTW3|A0A034VTW3_BACDO Anoctamin OS=Bactrocera dorsalis GN=ANO1 PE=3 SV=1
-------------------------------------------------NETLFFTDGVRSIDFVLAYKVDLDAS-------------------------
---QE----------------AINAHKRFKYEANLLQNGLQMEVDIR-EQQHIHFVKIHAPLDVLRRYAEILKLRMPMKEDYSRSRKPGAFSSLKSVVQF
FLRHIFVDER-YFPRRAYRFTAIYSRDKEYLFDI-HHRCFFTNAVRSRIVQFILDRQYFDNPDKAFGIDRMVESNVYCAAYPLHDGEIT---EKGTMREA
LYTHWASVKKWYRYQPLDYVKEYFGVKIGLYFAWLGFYTYMLLLASLIGIICFVYSLITLKDYVPVQDVCSNENNLTMCPLCD-RCDFWYLKETCFYAKI
TYLFDNPSTVFFAVFMSFWATLFLELWKRYSAEITHRWDLTGFDVHE----EHPRPEYLSRLGHVKNTRTRIDTNQEPVVPFWRMKFPATILSVSVVFLL
ILLAFVALVAVVVYRMSMLGTFKLNSSTMTTSSAIMLATASAAFVNLCLLYMLNYVYTQLAEYLTELEMWRTQTQFDDSLTLKIYLLQFVNYYASIFYIA
FFKGKFVGHPGKYNTIF-DYRQEECSSGGCLTELCIQLAIIMIGKQAF-NTILEVIMPKIWRKIMAIQVGLSRLKTHDVNKEKVERYLRDLKLLDWRSLF
PEYLEMVLQYGFVTLFVAAFPLAPFFALLNNIFEMRLDAKKLLANHRRPVSQRVRDIGVWYRILDSIGKLSVITNGFIIAFTSDFIPRLVYRAS-SEGHT
LAGYLNFTLSEYNITESDNLRSLAG---DDSNIRTCFYADFREPPTSPRKYYLTSTFYIILACRLAFVVVFENFVALVMILVRWCIPDMSVELRDQIRRE
VYLTNEIIIAKEAERARLGL----------------------------------------
>tr|A0A0Q3Z8Z7|A0A0Q3Z8Z7_ALLMI Anoctamin 7 OS=Alligator mississippiensis GN=ANO7 PE=4 SV=1
-------------------------------------------DKRHQSKDSVFFRDGVRRIDFVLSYVDDPNKD-------------------------
--------------------EEKKADRRREFESNLQKSGLELETEDKKENGKTYYVKIHAPWEVLITYAEVLNIKVPIKNDCTIEN----------PIDC
MLSPFRLPEKVMH-PDPDYFTAPFRKDRQELYLIHDESTFFSPSVRNRIVFYILTRCPYGTEKKKFGIKRLLSNGTYTAAYPLHDCQYKKSPHCDNERYT
LYMEWARFLRFFKEQPLDLIRKYYGEKIGIYFAWLGFYTEMLFLAAVVGLFCFLYGLFTMDANMSSKEICDPAGEIIMCPLCDVDCNYWRLNTTCRPSEY
SHLFDNVATLFFAIFMGIWVTLFLEFWKRRQARLKYEWDLVDFEEEQ--QQLQLRPEYEAKCTQKKKNPVTQEMEPY--LP-LTSKAVRFCISGTTVLFW
TSLIIASMIAVILYRLSVYAAFASIKNTQLQLTPQLATSVTASCLNFVIIMILNFLYERIAVWITDMEIPRTHLEYENRLTMKMFLFQFVNYYSSCFYVA
FFKGKFVGYPGNYTYMFSHWRNEECDPAGCLIELTTQLTIVMAGKQIW-GNIQEAIVPWIWNWWGRQRARCN-------PENLYSRWEQDHDLQRFLGLF
YEYLEMVIQFGFITLFVASFPLAPLLALMNNILEIRVDSWKLTTQFRRPVASKAHSIGVWQEILNGMAVLSVVTNAFIVAFTSDMIPRLVYYYAYSPNSP
MSGYINNSLSVFRVSSFSVKPKDQ------GDIDFCRYRDYRYPPDHELQYSHTMQFWHILAAKMAFIIIMEHVVFIVKFFVAWMIPDVPADVTARIKRE
KFITQKILHEYELNKLKE------------------------------------------
>tr|A0A0L0CJY0|A0A0L0CJY0_LUCCU Anoctamin (Fragment) OS=Lucilia cuprina GN=FF38_13116 PE=3 SV=1
------------------MTKLAPFED----PPEIELSAPNDYFEKHEPNPSLFFDDGVRSIDFVLVYKIDLQH--------------------------
-----QVL------------EEDHAEKRRVFEANLEAEGLEIERVCK-EKEQIYFVKIHAPLEVLRRYAEILKLRMPMKIPGVVRSTRSVFSSLKGIFTF
FMKHIYVDER-YFPRRAQRFTAIYSRDKEYLFDI-RQDNFFTPAVRSRIVQFILDRQRFTPKEMAFGIERLVTYNVYCAAYPLHDGEIY---EKNTMRHT
LSTHWASISKWYRYQPLDYVKEYFGVKIGLYFAWLGFYTYMLMLAAVVGLICFLYSLLTLKDYVPVQEICSNTTNITMCPLC-NWCNFWDLKETCFYAKI
SYLIDNPSTLFFTVFMSFWAALFLELWKRYSAEITHRWDLTGFDVHE----EHPRPQYLARLQHLPNTRTDTNKEP--TVPFWRMKFPAAVFSFSVVLLL
IALAFVALVGVVIYRVSMLAILKVGDSPMNTSSAIMLASASAAFLNLCFLYVLNYLYNHLADYLTEKEMWRTQTQFDDSLTLKIYLLQFVNYYASIFYIA
FFKGKFVGHPAKYNKIFDE-RQEECSSGGCLTELCIQLAIIMIGKQAF-NSVLEVIMPKIWRKIMALKVGLTRCSKEDKHHKDTERWWRDLKLLDWRSLF
PEYLEMVLQYGFVTIFVAAFPLAPFFALLNNILEMRLDANKLLTHHRRPVSQRVRDIGVWYRILDCIGKLSVITNGFIIAFTSDMIPRWVYRGLNSEDGS
LHGYLNFTLSEFRTSDSDSELRS---LSIKYNITSCKYTDFREPPTSPNKYYLSSTFYIILACRLGFVVVFENFVALVMILVRWCIPDMSVELRDQIRRE
VYITNEIIIEQEARRARFE-----------------------------------------
>tr|E0VCR5|E0VCR5_PEDHC Anoctamin OS=Pediculus humanus subsp. corporis GN=Phum_PHUM095280 PE=3 SV=1
-------------------DNVSRINDIEYA--SGGLLSGVDEEYRPPKSETLLFSDGKRRIDMVLVYEEEDLGVMRE----------------------
-------------------SEALKKEKRKRFKENLEREGLEFELEDKKFDEKTYFLKIHAPWQVMTRYAELMNIKMPIKRLISVKEEND-DGSIKAFFNK
---LFEYDHTRIP-DEPSFYKATFTRNEEDQFVVKDRESFFTGAQRSQIVWEILMRAKYDVT-EKVGIRRLLNDQTYIAAYPLHEGAYDEDNGFLYDRRL
LYLEWARPSKWFKKQPLWLVRKYFGDKIALYFAWLGFYTNMLALPAIVGVFCFLYGLGSLEDNIPGNEICDLKGNLTLCPMCDKACRYIKLGDSCMYAKM
TYLFDNPSTVFFAIFMSFWATTYLEMWKRQQSIIVWEWDLQNIED-D----EEPRPEFETSVKTFRINPVTR--EREPYMPLWN-KALRFLATSATVLCM
IFVVIGAVLGTIIYRISLVAVIYSGGGTLLKDHAKIFTSMTAALINLIIIMILTRFYHSLAIWLTNIENPRTQREYEDSFTFKIFLFEFVNFYSSLIYIA
FFKGRFFMHPGDTAAEFLKLKGDVCDPAGCLSELCIQLAIIMIGKQCL-NNVLELLYPKFWNWWYRRVHSSHT---KKGFTRKLTRWEEDYQMQDALALF
EEYLEMVLQYGFVTLFVAAFPLAPLFAFLNNIGEIRLDAYKMVTQSRRPLAERVQNIGAWYGILKGLTYTAVVSNAFVIGYTSDFIPRMVYKFVYSPTND
LRGYIKSSLSEFNTSDYTEDMGPEDD----PDPPICYYRGYRNPPNHPDPYDLSPQYWHVFAARLAFVVVFEHFVFALTGIMAYIIPDVPTSVRTQMLRE
NLLAKEAKYEKGLR----------------------------------------------
>tr|M9PI24|M9PI24_DROME Anoctamin OS=Drosophila melanogaster GN=CG6938 PE=3 SV=1
------------------------------------------------DPESLMFRDGRRKVDMVLAWEEEDLGV-------------------------
----------------MTEAEAKRRDNRRSFMENLIKEGLEVELEDKSFNEKTFFLKIHLPWRLETRLAEVMNLKLPVKRFWD--EENVNMQYWKDVWQR
LTKKIQLDQTLLE--GETTFKATANGNPEEQFIVKDRATAFTSAQRSLMVMQVLIRTPFDESD-RSGIRRLMNDGTYLGCFPLHEGRYDRPSGISLDRRV
LYQTWAHPSQWYKKQPLCLVRKYFGDKIALYFCWLGFYTEMLVYPAVVGTLCFIYGLATLEDNTPSKEICNEYGNITLCPLCDKACSYQRLSESCLFSRL
TYLFDNPSTVFFAIFMSFWATTFLELWKRKQSVLVWEWDLHNVDMD-----EENRPEFETNATTFRMNPVTREKEP--YMSTWN-RSIRFVITGSAVLFM
ISVVLSAVLGTILYRITLVSVIYGGGGFFVKEHAKLFTSVTAALINLVVIMILTRIYHRMAIKLTNLENPRTHTEYEDSYTFKIFFFEFMNFYSSLIYIA
FFKGRFFDYPGDDQARFFRLKNDICDPAGCLSELCIQLAIIMVGKQCW-NNFMEYLFPKFWNWWRQRKHKQATK----DESHLHMAWEQDYHMQDPLALF
DEYLEMILQYGFVTLFVAAFPLAPLFALLNNVAEIRLDAYKMVTQARRPLAERVEDIGAWYGILRIITYTAVVSNAFVIAYTSDFIPRMVYKFVYSETHT
LAGYIEHSLSIFNTSDYKEEWGASVSE---KDPDTCQYRGYRNGPKDYEPYGLSPHYWHVFAARLAFVVVFEHVVFVITGIMQFIIPDVPSEVKTQMQRE
QLLAKEAKYQHGIKRAQGDSQ---------------------------------------
>tr|A0A0P7WX40|A0A0P7WX40_9TELE Anoctamin-7-like (Fragment) OS=Scleropages formosus GN=Z043_112603 PE=4 SV=1
----------------------------------------------------------------------------------------------------
---------------------------------PARELGSDLFAHFEEEKTRVTYVLLSAPWSVLCYYAEEISLKAPLEVPTNL----HWSKK---VLDK
LSNLMAQDVPN---PPKDYYTCQFRNNKLERFLGENKDTFFTNTQRHQILYEILARTPYGVMKGEVGIDRLVAEKVFTAAYPLHEGPFKVAPCSLSMRQI
LFRYWARWACWRKYQPLDHIREYFGEKVALYFAWLGFYTGWLLPAAIVGLLVFLFGIWLMTTDV----PAG--GTFIMCPLCN-ICTYWNLSSICTTFKA
GLLFDNGGTVFFSMFMALWAVTFLEYWKRTSAVLAHRWDCSEFEEIE----ERPRPEFTAMAPMTLRNPVTGAEE--PYFPQ-HRRFNRTITGCMVIIVM
LSVVLIFLMAIILYRSILSIIIYRSKNSFLHLQAGRIASLTGSVLNLLVILMLSRLYTFLAQVLTRWEMHRTQTKYEDAFILKVFIFQFVNFYSSPIYIA
FFKGRFVGYPGKYHTFF-GIRNEDCGAGGCLIELAQELLVIMVGKQII-NNVQEFVFPKLRTWWQNRKHNPHGGNQGARKKPTLMPWEKDYKLLVCEGLF
NEYLEMVLQFGFITIFVAACPLAPLFALLNNWVEVRLDAQKFVCEYRRPVVERAQDIGIWFNILQVICHLAVISNAFLIAFTSDFLPRLYYRYTT--EGT
LKGYVNFTLATAPHSYA-------------ENQTTCRYYGYRDPEGH-----LLPEYYQLL----------AHVVFFIGRLIDMMVPDIPGEVEVKIKRE
HYMAKEALAENQVRLMIS------------------------------------------
>tr|F2TWL5|F2TWL5_SALR5 Putative uncharacterized protein OS=Salpingoeca rosetta (strain ATCC 50818 / BSB-021) GN=PTSG_11592 PE=4 SV=1
----------------------------------------------------------------------------------------------------
---------------------------------SLRDLGFELETE--SPDGELLFIKVHAPFELLLQEAEKSKIKKTLKEASHLQEQKSFADR---LFLS
LSQYLQPDVEE----EPDSFSADFRMCIRDQFENEDEDKFFTSGERSSLVWEKLTRVPYGAKDSQVGIKKLLTNGTFAAAFPLHDGPHKIDPYDVNDRKT
LYEVWGQLKLCFIFQPYDLIRKYFGVKIGLYFAWLGFYTYALLVPGILGFIVFINGLANYRQQRDAIDVCE--SNFTMCPLCNEGCERWNLTEACNMYQA
SYWFDNEATIAFAFFMSVWASIFIDFWKRRNAELGYDWDVLDFAEE-----ERDRPQFRG--TTKRKNPVTGKEE--KYYPG-YKRSVKQVGSFATMVVM
LAVVIIIVFSVIVYRIAVRAALAAQ----DGSQASTITAVTAGVINLAGIVLMNQVYGRLAVTLTDWENHQKESEYEGSLTSKIFLFSFVNSFASIFYIA
FFKGKFVGRPGAYTKLL-GYRQDECPPYGCMLELTIQLAIIMVGRQII-NNIVEMLLPAVMRKVRNIM-----APELKEKARRLLPWENEYLNLPQYGMF
PEYLEMILQFGFLSLFVSAFSLAPFFALLNNILEIRIDAHKLLTVYRRPPAQRAANIGIWDEVMTFISYFSVLTNGLVIAFSSNFIPREVWRYAH--DGT
LHGYIDAIYPLSPVDPAD-----------DPDFANCHYFGLREADGT-----RGQFYYEVIAARLGFLIIFEHIVFLCKFLFQWLIPDVPQAVTLAVKRE
EYLARLALDSALDDEVAD------------------------------------------
>tr|A0A061IBB7|A0A061IBB7_CRIGR Anoctamin OS=Cricetulus griseus GN=H671_3g8704 PE=3 SV=1
----------------------------------------------EQSKDSIFFRDGTRQIDFVLSYVEDTKKDS------------------------
---------------------ELKAERRREFEQNLRKTGLELEIEDKSEDGKTFFVKIHAPWEVLLTYAEVLGIKMPIKSDIPRPNYLPLSYM-------
-LGPVKLPATVKYP-HPEYFTAQFSRPRQELFLIEDEATFFPSSTRNRIQYWK--------------------------------PS--KSPTHINERYI
LRQNWARFSYFYKEQPLDLIRDYYGEKIGIYFVFLGYYTEMLLIAALVGLACFIYGLLSMENNQTSMEICDPNGQMIMCPLCDEVCDYWRLNTTCLHSKF
SHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEWDLVDFEEEQ--QQLQLRPEFEAMCKLKKM-----N--PV------T-K-------------M
GL-LLSSMVSIIVYRLSVFATFASFESETVKFTPQLATNLSGSCLNCIAILILNFFYERISAWITKMEIPRTYQEYESSLTLKMFLFQFVNYYSACFYVA
FFKGKLVGYPGKYTYMFNLWRSEECDPAGCLVELTTQLTIIMIAKQLF-GNIHEAFQPLIFNWWRRRKSRTN-------SEKLYSRWEQDNDLQVFLGLF
YEYLETVIQFGFVTLFVASFPLAPLFALINNIMEIRVDAWKLTTQYRRPVAAKAHSIGIWQDILYGMAIVSVATNAFIVAFTSDIIPRLVYFYAYSKTEP
LSGYVNNSLSVFLIDDFPNHTVPMGKKDF----ITCRYRDYRNPPDHENKYVHNMQFWHVLAAKMTFIIVMEHIVFLFKFLLAWMIPDVPKDVIEKIKRE
KLMTVKIIHDFELNKLKENLDYEYSNF---------------------------------
>tr|G1S826|G1S826_NOMLE Anoctamin (Fragment) OS=Nomascus leucogenys GN=ANO5 PE=3 SV=2
----------------------------------------------QQSKDSIFFRDGIRQIDFVLSYVDDIKKDA------------------------
---------------------ELKAERRKEFEKNLRKTGLELEIEDKREDGRTYFVKIHAPWEVLVTYAEVLGIKMPIKSDIPRPKHTPISYV-------
-LGPVRLPLSVKYP-RPEYFTAQFSRHRQELFLIEDQATFFPSSSRNRIQYWK--------------------------------PS--EPPNPTNERYT
LHQNWARFSYFYKEQPLDLIKNYYGEKIGIYFVFLGFYTEMLFFAAVVGLACFIYGLLSMEHNTSSTEICDPEGQMIMCPLCDQVCDYWRLNSTCLASKF
SHLFDNESTVFFAIFMGIWVTLFLEFWKQRQARLEYEWDLVDFEEEQ--QQLQLRPEFEAMCKHRKL-----N--AV------T-KEMEPYMPATVTLWM
SL-VVTSMVAVIVYRLSVFATFASFESDSVKLTPQITTSLTGSCLNFIVILILNFFYEKISAWITKMEIPRTYQEYESSLTLKMFLFQFVNFYSSCFYVA
FFKGKFVGYPGKYTYLFNEWRSEECDPGGCLIELTTQLTIIMTGKQIF-GNIKEAIYPLALNWWRRRKARTN-------SEKLYSRWEQDHDLESFLGLF
YEYLETVTQFGFVTLFVASFPLAPLLALINNIVEIRVDAWKLTTQYRRTVASKAHSIGVWQDILYGMAVLSVATNAFIVAFTSDIIPRLVYYYAYSTTQP
MTGYVNNSLSVFLIADFPNHTAPSEKRDF----ITCRYRDYRYPPDDENKYFHNMQFWHVLAAKMTFIIVMEHVVFLVKFLLAWMIPDVPKDVVERIKRE
KLMTIKILHDFELNKLKENLGINSNEF---------------------------------
>tr|G1SCV2|G1SCV2_RABIT Anoctamin OS=Oryctolagus cuniculus GN=ANO5 PE=3 SV=2
----------------------------------------------EQSKDSIFFRDGIRQIDFVLSYVDDLRKDA------------------------
---------------------EIKAERRKEFEQNLRKSGLELEIEDKREDGRTYFVKIHAPWEVLVTYAEVLGIKMPIKSDVPRNEDTPLTYM-------
-LSAVKLPASVKYP-HPEYFTAQFSRHRQELFLIDDPSTFFPSSARNRIQYWK--------------------------------PS--EPPNPVNERYT
LHQNWARFSFFYKEQPLDLIRNLEGRRMVVYVVLLEYFTLIEYFTLIEYFSCFLYLFLSFKSNFSSFDIIDRFQQMTLASSKNYVTCYWNLAGFCLAQKS
YHLLFSKHLLIMLVFIHAIVTLFLEFWKQRQATLEYQWDLVDFEEEQ--QQLQLRPEFEAMCKHRKM-----N--TV------T-KEMEPHMPATVTLWM
TL-VVACMVAVIVYRLSVFATFASFQSESVRLTPQLTTALTGSCLNFIVILILNFFYEKISAWITKMEIPRTYQEYESSLTLKMFLFQFVNYYSSCFYVA
FFKGKFVGYPGQYTYLFKTWRSEECDPGGCLIELTTQLTIIMTGKQIC-GNIKEAIFPLILNWWRRRKSRTN-------SEKLYSRWEQDHDLESFLGLF
YEYLETVIQFGFVTLFVASFTLAPLLALMNNIIAIRVDAWKLTTQYRRPVAAKAHSIGVWQDILFGMAVLSVATNAFIVAFTSDIIPRVVYHYAYSITHP
LQGYVNNSLSIFLTADFPNHTLPVDKRDF----TTCRYRDYRHPPDHTDKYLHNKQFWHVLAAKMTFIILMEHIVFLFKFLLAWMIPDVPKDVVDRIKRE
KLMTVKILHEFELNKLREDLGVQPSEL---------------------------------
>tr|Q4S1F6|Q4S1F6_TETNG Anoctamin OS=Tetraodon nigroviridis GN=GSTENG00025579001 PE=3 SV=1
----------------------------------------------------------------------------------------------------
---------------------PLHDERRKIYEANLEKVGLELETEDKSEDGKTSFVKIHAPWEVLATYADVLKIKVPFKNDI--PDNKDIPMNWL-----
-STPFRLPGH-IMHPEPDYFTAPFNKSKSDFFLIDNQETFFPPSTRNRIVRYILSRCSYFKDKDKKGIKRLLNNGTYTAAFPLHDSRYWTRPNCESERYY
LYKYWARFFCFFKEQPLDLVRKYYGEKIGIYFAWLGFYTEMLLFAAIVGTICFIYGFLTYDDNQWSKEICSEAGNIVMCPLCDKKCGYWKLSSTCNSSWQ
SHLFDNVATVFFAIFMGIWVTLFLEFWKRRQARLEYEWDLVDFEEEQ--QQLQLRPEYETKCSKRKLNRITQNTICVRRSVHLEGCVSAMSLSCCVSVLK
ISLIIACIIGVIAYRLAVFAAFASIKSPTLKITPQLATSVTASCINFVIIMILNLMYEKVAIWITDMEIPKTHLEYDNKLTMKMFLFQFVNYYSSCFYVA
FFKGKFVGYPGDYAYMFSKWRNEECDPGGCLIELTTQLVIVMTGKQVW-GNIQEALVPWLMNWWGSRKARRHP-------ESLYSRWEQDHDLQGFLGLF
YEYLEMVIQFGFITLFVASFPLAPLLALFNNVIEVRVDAWKLTTQFRRPVASKAHSIGAWQEILNGMAILSVVTNAFIVAFTSDMIPRLVYMYAYQPDGN
MKGYINNSLSVFNISQIPEANSPED------EVNPVWYRDYRYPSGHEKQYAHTMQFWHILAAKLAFIIIMEHVVFLVKFFVAWMIPDVPSDVRARVKRE
RYLVQEYLHNYEVEKLKDQL----------------------------------------
>tr|L9L0W1|L9L0W1_TUPCH Anoctamin OS=Tupaia chinensis GN=TREES_T100008854 PE=3 SV=1
-----------------------------------------------QDSRGNFFRDGKTKIDFVLVWEEKLRPPRRAGRQR------------------
---------------------LLQRRWRAKFQRNLRAAGLLLEEEHSQGARSVHFAKLSAPWELLVFYAEELSLRAPLQRP-N-PDSDGS----AELLRR
LRNPLQQ---HVPNKPLDFYTCSFRRSKMDRFLGDSHDSYFSNTQRHQVVAEILARTVYGKRKAEMGIARLLAEGVFTAAFPLHEGPFELPGADLNPRQL
LYSYWACWGRWHKYQPLDHIREYFGEKVAIYFAWLGFYTAWLLPAALVGTLIFISGLVTMGTNTPAEEICASGGAFLMCPLCN-TCATWNISEICPMAKL
GYLFDHPGTVFFSIFMSFWAMAFLEHWKRKSATLAHHWDCSDFRDEE----ECPRPEFATLAPQMAWNPVTGLKEPL------RNRLPRLLTGSAAILIM
LCVVMIFLVSVIMYRGIISIAMFHTGNPMLMTQAGNIANISSTVLNLVLILLLGQVYTSLAEQLTRWEMHRTQSLHEDAFTFKVFIFQFVNFYSSPFYVA
FFKGRFVGYPGRYGTLLG-MRNEDCGPGGCLIELAQQLFIIMVGKQLV-SNVEEFVVPKLKAWWQKRQLAELR---AVQVGQELQRWEEDYELLECEGLF
QEYLEMVLQFGFITIFVAAFPLAPLFALLNNWVEIRLDAHKFLCNYRRPVAQRAQGIGIWLLLLEAMAHLSVIVNAFLIAFTSDFLPRVLYQYEH--HNQ
LHGFVNFTLAPAPPAYLAQ-----------GNHTPCRYKAFRDAQGN-----LTLFYWKLLAVRLSFIIAFEHVVFFFLRLIAWLVPDVPAALATKIKRE
RYLAKQALADNREVLLS--------------VCKAHGPWSHPHQNDYVP-----------
>tr|A0A0Q4AH23|A0A0Q4AH23_ALLMI Uncharacterized protein OS=Alligator mississippiensis GN=Y1Q_031960 PE=4 SV=1
-----------------------------------------------PSARGNYFRDGATKIDFVLVWEEKLRPPKKRGRPR------------------
---------------------ERHEQWKRKFLKNLRGAGLLTEKEETL-RKTIHYLKLSAPWDVLVYYAEELCLRAPLQQP-N-PDCNSS----DEVLRR
LRNPMYQ---RVPNKPSDFYTCAFRKSKLDRFLGDSRDTYFTHTQRHRIVYEILARTVYGKRKAEVGIERLLNEGIYTAAFPLHEGPFEMPGEELNPRQV
LYHFWAQWRCWYQYQPLDHIREYFGEKIAIYFAWLGFYTAWLLPAATVGTFVFLAGLVTMGTNTPAQEICESGGQFLMCPLCD-TCQTWNISEICPMAKV
GYLFDHPGTVFFSVFMSFWAVTFLEYWKRTNATLAHHWDCMDFQEEE----ERPRPEFAAMAPQMEQNPVTGVKEPE------RARLSRILTGSMAIVIM
LCVVMIFLVSVIMYRGIVSMMMYHTGNTILMTQAGNIANISSTMVNLVLILLMSQVYTSLAEKLTRWEMHRTQTLHEDAFTFKVFIFQFVNFYSSPFYVA
FFKGRFVGYPGQYGKLLG-MRNEDCGPGGCLIELAQQLFIIMVGKQIV-SNIQEFFIPKLKAWRQKRKLARVR---GSQISQEPRRWEEDYELIECEGLF
EEYLEMVLQFGFITIFVAAFPLAPLFALLNNWVEIRLDAQKFVCEYRRPVAYRAQDIGVWFFILEVLAQISVIINAFLIAFTSDFLPRLLYQYEH--DSQ
LHGYINFTLAYAPQSYVA------------SNHTLCRYKAFRDTTGN-----YTLFYWKLLAIRLGFIIAFEHVVFFCLRLIDWLVPDVPESLEVKIKRE
RYLAKQALADNHDVLLT--------------VSPDSPSPA----SSLSP-----------
>tr|A0A084VUQ2|A0A084VUQ2_ANOSI Anoctamin OS=Anopheles sinensis GN=ZHAS_00009326 PE=3 SV=1
-----------------------------------------------LDPESLMFRDGRRKIDMILCYEEEEQGV-------------------------
----------------MTELEALKRHQRKLFHENLVREGLEIEVEDKMFDGKTYFVKIHIPWRTESRYAEVMNLKLPVKRFISVKVIFGQQNKILGYWNR
LMSLTEYNHERI-EKEPSFYSATANGNPEEQFIVKDRCTSYTSAQRSLIVMQILMRTRFDETVNNVGIRRLLNDGTYLACFPLHEGRYDKDSGALFDRRL
LYLEWARPIKWYKKQPLCLVRKYFGDKIALYFCWLGFYTKMLYAPAIVGLFCFLYGLASMDDNIPTKEICDEKGKTILCPLCDRACSYQQLHESCFFAQL
TYLFDNPSTVFFAIFMSFWATTFLELWKRKQSVLVWEWDLQNIENE-----EDMRPEFETTVKTFRINPVTREK--EPYMPTWT-RAIRFFATSSAVLFM
ISIVMGAVLGTIIYRISLVSVIYSGGGSFFRTHAKLFTTMTAALINLIIIMLLTRIYHKLALYLTNMENPRTQTEYEDSYTVKIFVFEFMNFYSSLIYIA
FFKGRFYDYPGDDVARKSEFKGDICDPAGCLSELCIQLAIIMVGKQCW-NNFMEYFFPAFYNWWRRRKHKQLTK----DETHLHMAWEQDYHLQDPLALF
DEYLEMIVQYGFVTLFVAAFPLAPLFALLNNIAEIRLDAYKMVTQSRRPLAERVEDIGAWYGILKIITYTAVVSNAFVIAYTSDFIPRMVYKYVYSPQFS
LHGYIEHSLSTFNTSDYKEEWGTKTE----SDPDTCQYRGYRNGPDADEQYGLSPHYWHVFAARLAFVVIFEHIVFVLTGIMQFIIPDIPIEVKTQMQRE
QLLAKEAKYQHGLKKSHETDY---------------------------------------
>tr|A0A084WPM2|A0A084WPM2_ANOSI Anoctamin OS=Anopheles sinensis GN=ZHAS_00020494 PE=3 SV=1
--------------------------------------------SLWKSRTWKYFQDQKRIVDYVLAFNGEETD--------------------------
---------------------PIAVAKRTIFQRNLEAEGLEIETEN---CQRIHFVKIHVPANVLSHYCEIMKMQMPMRKDEKIHEFS-IQSTLVRWFRR
PLFNFVIDRK-KFAEPEYRLLYEYSRDKPYLFND-HDPNFFTPTIRIAVAHFILERTYYSENKKDIGIRRLVEDLVYMDAYPLHDGCTD--QKSSCQRAL
LLEEWASISKWIKHQPLDHIKEYFGVKIAMYFAWLGFYTHMLIPASVVGLICFFYGLLTYPANQMSKEICGD-NTTVMCPQCDRLCDYWMLNTTCGVSKL
SHIFDNEMTIVFSIFMSVWATLYLEMWKRYSSRIQHRWGITEYCSLA----EPPRPQYLSRLKNIKKTM--FNTGPEPSPPFWTKKFPSFLCSYSVIFLF
IMLTIMAVFGIVVYRMSLMTSRNIYGDGGSVSRKLIIFPAMTAVINLLASTVLTYVYQYVAVYMTDVEYRRTQTEYNESLNLKIYLFEFVNYYSSIFYIA
FMKGKFPGYPAKYNRILT-LRQEECSPGGCLMELCIQLAIIMVGKQAI-GGITEILIPFLVQKFKEFRSVLGIEDENGERLICCNQWTKDFNLINWRSLF
NEYLKMVIQYGFITIFVVAFPLAPFFALLNNVFETRLDAKKFLLYYKRSVPQRVRDLGIWYNIMHVVGKVAVISSAFIIAFSSNFIPRLVYMSVVNPTGT
DEGFVNHTLAYFNVSDFEPNVAPEESKL--HNVSICRYTEYRNSYDDPHPYKRPLIYWQILALRLTFVVIYQNLVSFVQIVVAWAIPDVPSRLQDQIKRE
QYLTNEYIIEQEKLKIQRTAT---------------------------------------
>tr|Q7QEP9|Q7QEP9_ANOGA Anoctamin OS=Anopheles gambiae GN=AgaP_AGAP000095 PE=3 SV=4
--------------------------------------------TQWKSRTWKYFQDQRRIVDYVLAFNGEDEN--------------------------
---------------------AEAKQRRAIYQRNLESEGLQIETEN---CQRIHFVKIHVPENVLSHYCEIMKMQMPMKKEDKIRDFS-IQSTLVRLFRR
PLFNFVIDRQ-KFAPPEYRLMYEYSRDKPYLFDD-REQNFFTPSIRIAVAHFILERTYFSEAKKDIGIRRLMEDQVYLDAYPLHDGCTD--LRSSCQRAL
LLEEWASISKWIKHQPLDHIKEYFGVKIAMYFAWLGFYTHMLIPASVVGLICFFYGLLTYPANRISQEICDD-NGTIMCPQCDKYCDYWYLRTTCNISKL
AHIFDNEMTIVFSIFMSVWATLYLEMWKRYSSRIQHRWGITEYCSLA----EPPRPQYLSRLKNIKKMM--FNTGQEPSPPFWTKKFPSFLYSYSVIFLF
ILLTIAAVFGIVVYRMSLMTSKNIYGDGGSVSGKLIIFPATTAAINLLASTALTYAYQYVAEYMTNVEYRRTQTEYNESLNLKIYLFEFVNYYSSIFYIA
FMKGKFPGYPAKYNRILH-LRQEECSPGGCLMELCIQLAIIMVGKQAI-GAITEILIPFLVQKFKEFRSVLGIDSENGERLICCNQWTKDFNLINWRSLF
NEYLKMVIQYGFITIFVVAFPLAPFFALLNNVFETRLDAKKFLLYYKRAVPQRVRDLGIWYNIMHVVGKVAVISSAFIIAFSSNFIPRLMYMNVVNPTGT
DEGFVNHTLAYFNVSHFEANAAPENSTF--SNITICRYSEYRNPPDDPRPYKRPSIYWQILAIRLTFVVIYQNLVSFVQIVVAWAIPDVPTKLQDQIKRE
QYLTNEYIIEQEKLKMALSGT---------------------------------------
>tr|E0W2D0|E0W2D0_PEDHC Anoctamin OS=Pediculus humanus subsp. corporis GN=Phum_PHUM590010 PE=3 SV=1
-------------------------------------------------GNSIYFSDGIRKIDYVLVFTKNLEDPKK--RKSLDKIATESITNILSQDNI
DL-------------------SKKEQWRNQFLTNIKKSGLEIEEEIIEGKKAFIFLKIHATWPVLCRYAEELNLRAPLLKTSDLNGSDTFLKY-------
-FGITNPMELTMPTQPLHFYTCPFRENKLHRFLGENKDTYFTTIQRIWIVNEVLSSAVFGTQKGEVGINRLVHEGVFNAAYPLHDGPYLPEPEELNPRQI
LYEYWARWGRWYKYQPLDHIRNYFGEKVGFYFAWLGFYTSWLFPAAAVGILVFLYGLITVFDNPYANDVCEKPGKYKMCPQH-EFGKFWDLYDICTYIRI
SYLFDHPGSVFYSIFISFWAVSFLEYWKRKCVTIAYQWDCTDFQGVE----EKPRAEYAAKAPYIAVNPVTGVREPM--FP-KNERGKRIATGLGLVFVM
ISVVIIFIFAIIVFRIAIAIPLHNMN--MTRGYAHTMANLTGAGLNFIIIMIMSKFYEWLAQKLTRWEMHRTQSEYDDNYTFKVFVFQFVNFYSSIFYIA
FFKGRFVGYPGNYVYIFNM-RNEECEEGGCLIELAQQLAIIMIGKQVI-NNFMEVGMPWAKSWWLKIQVKRKNS---KNSNSEHIQIQEDYYTSPNDGLF
QEYLEMVLQFGFITLFVAAFPLAPLFALLNNWVEIRLDAQKFVCHTRRVIPERTEDIGMWFKILQYLAHIAVITNGLLIAFTSRFLMKLLYQYEYN--WS
EKGYYDFILSWA-----PNG----------TYTERCRYRGQRDENGN-----YTMFFWKLLAVQFAFVLAFEYFVFTVCRLIDVFVADVPPKVDIKIRRE
RYLAKQALLDNSLNNSERI-----------------------------------------
>tr|A0A0K0E0M2|A0A0K0E0M2_STRER Anoctamin OS=Strongyloides stercoralis PE=3 SV=1
----------------------------------------------SWEKEACFFSDGIRIIDYVLAYEDERFNAESDI----------------ENEQI
IMD---EKETGREYGSIK---KTKAVKRRIFQENLIALGLDIEEMPSHSSNKIIFVLIHAPFHVLCKQAEILKLKMPIIHSEEVNQVNGWLDTW--LIKK
FRTTMKPELERRFE-IKPKFRSPFIEERIECFENHDPDNFFPRAERSRLVYDLLLRTKYNSEESQIGIERMISRGIYYDAFPLHEPKKQLNINETTDREL
LYKYWASLYSFWRLQPLDLIKRYFGTKIGIYFAWLGYYTKSLIWPSMIGLIIVLIAVSTSINDIPSNDVCSSDEKVYLCPTCEKYCNFQKLRNNCVYAKL
TYIFDNYYTVIFAVVMCLWGTLFLEGWKRFHSEIAYKWGMLDFEVED----ETMRPDFQSKIKTKRINPVSKEEEPR------KEKLFRWFCSGMTVLFF
ICLVIAFAVGVIIYRVSFTFSLYGSDNEFYRNNAIIITSLLAGFINVCFIMILNRCYNWLAFKLTVWECPRTQTDFDNSYALKVFLFQFVNYYTSLFYIA
FFKGRFNSVPNALDKTNDDTSLEQCDPSGCMVELVIQLGTIMIGKQMF-TAIIERLLPKFYIWFASLKNKSAKKKNPQKEDKVMNQCDLDYSLNQVQYLF
DEYLEMVIQFGFVTLFVTAFPLAPMFALLNNFIEVRIDAQKFICTFRRPMPAHAKNIGVWEGILSGISYTAVLVNACIIAFTSDFIPKLYYLFFKS-NGD
LQGYMDYSLSYFDATLVSNSTIY-------NDVNICRFRGFYRPTCKFDDYNVNDDWWKMMVMRCAFVLIFEHFVFALKVLIAYIIPDIPTKIVYQIQRE
RHLSRKAMLNQH------------------------------------------------
>tr|F7BTQ0|F7BTQ0_MONDO Anoctamin OS=Monodelphis domestica GN=ANO7 PE=3 SV=2
----------------------------------------------------LDFSPKPERIDFILVWEEIGSKKEDKGKRKN-----------------
--KKA------------KRKEYAHRIWRWKFLEQLQATGIHMEQHIVKRKRSIHYVLLGAPWTVLCHHAEILRIKMPLQAMPSQSNWSDLMRK-LGIWN-
---PLYQEVP---QTPQDYYTYPFQESELSRFLGENPQTFFASTQRHKIVYEILEKTPFGHQRGLFGIQQLLSQKVFHAAFPPHDGPYQIPPHELNQRQI
LFRYWAKWSKWRKYQPMYHIRRYFGEKIAFYFAWLGFYTAWLLPASVFGIVVFLSTFFGSSADVPTDEICNASLDYEMCPSC-EDCPFWKLSTICEAVKT
GQLFDNKGIVIFSVFMSLWAVMFLENWKRKSARLAYQWDCLDSKVSRSPCEPLLQARGHFTARK--LE---GSDEGHPAGLDWSSQLPRFVLQAA-----
-VVTLL-LIAIILYRAGIAILVSKSSNIFFLTWVTQIANFTSALLNLSFILLLIKIYIPIAYVLTSWEMHKTQSKFEDALVWKVFVFHFVNIYSVPIYIA
FFKGRFSGYPGHYGTFF-GMQNENCINNSCLIELAQEMLVIMVGKQIF-NTLLEIFIPKLQSWKHKHKLRSSRKR--KKEKTSEILWEANYELLESQGLF
QEYLEMVIQFGFITIFVASCPLAPLFALLNNWLEIRTDAQKFVCQYRRPMAEKAQNIGMWFFLLQFITHLAIISNAFLIAFTSNFLQRTYYKYAYAW--D
LHGYTNFTLAQAPPGDAQGSSEE---LREGKAHLSFRYQAFREDDGQ-----HSFTFWKLLAIRLAFIVVFEHLIFFLGWLNDLVGPDIPASVKIEEKQE
------------------------------------------------------------
>tr|G7Y2S8|G7Y2S8_CLOSI Anoctamin (Fragment) OS=Clonorchis sinensis GN=CLF_100151 PE=3 SV=1
--------------------AVCDSRSIVWQPSGGLLVKN----------RDLYFTDGKRSIDYVLAYSRTKTTEVHAAKRTAFLKGARCCGQILGRVGP
SPPTEPIQPTSAAIPVYPEPNPQQKWSRKESTSSMDRYRFRAEHEESADLSDLVFVKLHAPWKTMERYAEMFNFRKPLKMDPEMPSCSD-----------
---CCDVDKSVLK-PLRNTFTWPFQKQRLYLFDIQNQDEFFTAVERAMVLDYILRRTPCVFEDNDVGITKMLSDGVFSAAYPLHELSESREFNCVNNRIL
LKRYWASYKSFGRPQPLDYIRYYFGEAVAFYFAWLGFYTSCLAPVAFLGVLIFLFGLIGMFNDPIVKDVCEYGSSIIMCPLCDVRCQFWRLNSSCLRSKL
TRLVDNEGTVLFGVIMALWAILFLELWKRRQVSLAYQWSVYSLEPVD----QPPRPEFLALLQKGFPSK--LNSGEEPVVPFWRMRVPCFCVSFTSVLFG
VLLTLACLVGVILYKLVMKVVFYQQPNEFVQSVAGMLTTITGSVINLILIFILKFIYNRLAIKLNDLENHRTQVEYDNSLTLKLYLLQFVNYYSSIFYIA
FIQGTTAAVPGADKSIV---QSTGCDQGDCLFELFLQLVIIMVGKQLL-NFIQETMMPVILRLIRKVRADCQRRHEVKTRSDRLLACRSDYTLLDPRPLF
DEYLEMMIQYGFITMFVPAFPLAPFFGMLNNLFEIRGDAKKFVNQYRRPVLERVGTIGIWYSILLVLSSLAIRTNACVIAFSTQFIDRWVYRMHYSADHT
DAGFKNFTLSYMDSSRFPGV----------SNTTYCRYDDYRKPPWEDPEMSHTLIFYHVLAVKFIFVFIFEIWVTVLTSLIAAMIPDVPKRVKKRIYFE
ANETNRLILDAELHHKQKRP----------------------------------------
>tr|F2U1Q0|F2U1Q0_SALR5 Uncharacterized protein OS=Salpingoeca rosetta (strain ATCC 50818 / BSB-021) GN=PTSG_02268 PE=4 SV=1
----------------------------------------------------------------------------------------------------
-------------------------------------------------WMRVVFVKMHVPFTVRCAVAQKLQLMMPLKRSIRLARRVGPALAVNSAINE
QDAFLILDDEEIDEETLQEITAEFSLVRASAFRNSKPDLFFTPAQNLRLTRQILLERPFTKSVRSRGYQLLVADGAYSAVFPLHDTTAATTNPYANLWLK
LVLFWSNWRNWRHHQPLRLVKNYFGEKVAFYFLWLEFYTTWLVAPALLGFVVFFLGFALQANRTDVKEYCAS--NKTMCAVC-SSCDQFTLQESCNAYKT
GYLFDNGATVVFSLIMSVWSTLFLEFWKRTQNRKAYAWRVRNFEE-T----EPHRPQFRSEGVK-------TDTGPKPFFP-FNKRLRRYIVSFLTVTVM
LGIVILAVVGVILARTVIRTRLYESSSESVSKASGAITSVIGASLSLFIILALGKVYARIALTLTRWENHERESEFERALAIKVFLFEFVNNFASIFFVA
FFKGQFIGRPGKFVEFF-GYRQDACPEYGCLIELTIQLSVIMVGKQSM-GNVKEVVIPYLFGVWKRWSLARRMLHKDDKPFNKILPWAVQYGYTAYPGLF
REYLEMILQFGFTTLFVASFPLAPIFALLNNIVEIRLDAKKHMHVLQRPFGFGAENIGIWQHVLSWVSIVAVITNAFVIAITSSFIPRYVYTRL---NGD
LAGFVDASLAKSPVTDPT------------SNQFDCYYSGYRNPDGS-----YSTLHFQIMMARFAFVLIFEHVVYTFKYLLSLVIYDVPSDVEIKIRRE
EYQAKIALDRE-------------------------------------------------
>tr|F2UIG4|F2UIG4_SALR5 Putative uncharacterized protein OS=Salpingoeca rosetta (strain ATCC 50818 / BSB-021) GN=PTSG_08258 PE=4 SV=1
----------------------------------------------------------------------------------------------------
---------------------EKRERERLRFELNLMRKGLVIERESS--GKHIAIVKVHCPFKRLCERAQVMQMKLPLKKDYERLQNDEVLALKY-RLRR
VFEAVLPDDASRFD-TDRSSTAHFSIEHAEKFENETPHKFFSPAQRSVLVRYILLNTKYGHNETKVGIDRLMRKGTYVDAFPLHDSSFDLPNNAYGLRAI
LLETWGRFWCVLRAQPLGLVREYFGEKVAFYFAWLGFYTTWLIIPSVVGFLTLFYGVAQFQGRADTTQVCQS--NVTMCAVCD-TCEKWQLNSSCTAAEA
TYIFDNEATIAFAFFMSLWATVFTEYWKRSQAELSFDWNMVDHDD-F----EPLRPQFRASTTRKNLI-TDQ-NEP--HYPAYR-RYLKYILTASTVLTV
CATVIIILISTIVYRIAVYTAYVTR-QPDQQDQASLIASGTAAVINLILIITLSFFYRYLAVWLTDWENHKTTSKYEQHLTIKIFTFQFFNSFGSLFYIA
FFQHQDIGVPGDYDT-FFGYQSDSCPAYGCLLELTIQLAVIMVGRQAF-NNVLEIGLPLLKAWWRKCRLRLKT-----TQHNDLLPWEEDYLLLDALGLF
DDYLEMCMQYGFITLFVASFPLAPFFALINNIFEIRVDASKFIGLWRRPIAERAAGLGLWRQVLEFLTLASVITNGMVISFTSNFVDKLVYRE---SRGS
LDGFYL---AITAES---PYDGPL------DIYRNCRYFGVRDADGE-----YKKLFYEILMGKLAFFIVFEHVVFLTKFLAQVIIPDEPRWVTIARKRE
VYQARAIIEG--------------------------------------------------
>tr|E4X0U9|E4X0U9_OIKDI Anoctamin OS=Oikopleura dioica GN=GSOID_T00014907001 PE=3 SV=1
----------------------------------------------------------------------------------------------------
----------------------KHRKFVECFERNLLAEKLFVERRMEINNKSKEFVLIGISEELLEDYAEKLEIKLPEKESYRFDPMSP--NLLAPMWQK
LANKFYHKKEHYIDSELIKLSNPDSG-KLDHYTNNDLKKVFSNSVRIRVIQYILKHTAYGKNT-EVGIDRLLAEEVYEDAYPLHEADEEVKIKESNLRTI
LRETWASWAKSFYFQPLFLVKRYFGPQIGIYFTWLGWYTQMLILPSALGLLVTLMGFAVFDDSPVQRAMCND--TRIMCPPCDRSCRFTVLDDSCASAKI
SAAFDNKWTVIYALFMATWAKIFCHLWTRKEAKMTNDWNLTE--DSI----DSVRVQFENRAKKMQERRGNLNKEEGSYKVSYVRKLPYLFVSVSIILTL
CLIIFG-VLTVQLYRLWMASFLTGLWNDHITENSVLIASASSVCLSMVFIYSLDWVFRLVASWLTELEMPKLDTAYEKSYTLKVFMFNAVNFWGSIFYIA
FIKGHGTGTPLRYSRWQGYYRLEECHPAGCLMEVSLQLGIILMIKQVV-SNFVELAWP----WWNARKQKKINR------GSDEKPWVRDYLLAKNLCLL
NEYQEMAIQFGFITIFVATFPLAPFFALMNNVIEIRLGAYKFIKLHRRARFVMARSIGAWVGILRTVSSIAVLTNALVAGYTSDIVPRVVYSLMYAQNEC
YKGYVDWSTQSVHISELDYGHRENNDFFKQDARCKCYYRGFDTEP-----------FYIVLSARLMFILIFEHIVQFMKWTVLRMLPNQTEKLKENLKKE
R-----------------------------------------------------------