>seq_1
QEGEFDEMIMEMDMRLENEHTLPNWSYQKKWIPAPLDAADKQIVGDVVIFADPLGLADQLKSFANSEQTYITVEPGQAFKQLTHTHFIIHPNRPSDYEQL
FETLRSYGVSVKHIIHLWNYTNQEDKLYVSKAKQAQKTGSMSALFLTKAISVYEEQVAITFVSTHAMNVPEDHIHDVEKATTAGLMTAVQHEWPFIKVQC
LDFSLAESVSSHSHAMAMMAELTHDQDCHVAAYRQGVRYIPFLAPLHLEKEQKRKEPPFESSGLYVITGGLGGIGRLVSEQLLTSYQAHLVLLGRKEREA
LSSDQQETLSLLEKQAKVHGGKVLYEKADITAEKEVEAIISRHEVAGNRRLDGIIHFAGIIQEELLADMTSVSLNDMYEAKVYGTIALHEAASKRRNVLF
LSSSSARTLKGGMTVGAYCAANEFVEQFAHYQKLTSTVKPYCFSFSMWDEIGMSEGSMIKGMLKERGYLPISKQAGFQTMLACLMTDAPLIYTGLDRSKK
EIHEMIHADAEMQTEQTFYVFFKTDQTKAVEERLYQSIHTCLQSRLSGEYAVHLFPEEYWKETEDGSPDEAYFHELIEESGMDADNRAPHTETEKLLAHI
WSELLDVSDVSCGDHFFLLGGHSLKATQMLSAVRQKTGFDVPLAVLFEHTRLGELADWIDSNAKADEVIPMR
>tr|K2MKW1|K2MKW1_9BACI Nonribosomal peptide synthetase subunit OS=Bacillus xiamenensis GN=BA1_08356 PE=4 SV=1
QEGEFDEIIKEMDIRLENEHTLPDWSYQKQWTPAPLDAADKQTIGDMVIFADTLGLADQLRSLSNSEQASITVEPGQTFKQLTHTHFIIHPNRPSDYEQL
FETLRSYGVSVKHIIHLWNYTNQEDKLHVAKAKQAQKTGSMSALFLTKAISVYEEPVAITFVSAHAMNLPEDHTHDVEKATTAGLLTAVQHEWPFIQVQC
LDFSLTESASSHSHASAIMAELTHDKDSHVTAYREGVRYIPLLTPLHLEKEQRVKKPPFEASGLYVITGGLGGIGRMLSEHLLTTYQAHLVLLGRKEQEA
LSAEQQETLSLLKEQAKVYGGTVLYEKTNITDAKEIEAAISRHEVTRDQRLDGIIHFAGIIQEELLADMTSVSLNKMYEAKVYGTIALHEAASKRQNVLF
LSSSSARTLKGGMTVGAYCAANEFVEQFAHYQKMTSTVKPYCFSFSMWDEVGMSEGSMIKGILKERGYLSMSKQAGFRTILACLMTDAPLIYTGLDRSKK
EIQEMV--DAEMQTEQAIYVFFKTDQTNAVEERLYQSIHTCLQSRLSGEYTVHLYPEEYWKETEDGMPDEAYFHELIEESGLDSENRAPQTETEKLLAHI
WAELLDVSDISCGDHFFLLGGHSLKATQMLSAVRQRTGFDVSLAVLFEHTRLGELADWIDSHAKADEAIPMR
>tr|A0A081L7S4|A0A081L7S4_9BACI Peptide synthetase OS=Bacillus sp. DW5-4 GN=BA70_09620 PE=4 SV=1
QEGEFDEIIKEMDIRLENEHTLPDWSYQKEWTPAPLDAAEKQIVGDIVIFADALGLADQLKSLSNSEQTYITVEPGQEFTQLTHTHFIIHPNRPSDYEQL
FETLRSYGVSVKQIIHLWNYTNQKDKLHVAVAKEAQKAGSMSALYLSKTVAVYEEPVEITFVSAHAMNLPEDQTHDVEKATTVGLMTAVQHEWPFIKVQC
LDFSLTESASSRSHASAIMTECTYDKRSHIAAYRGSVRYIPLLSPLHLEKEQKMKKPPFESSGLYVMTGGLGGIGSLLSEHLLKSDQAHLVLLGRKEREA
LSAEQQDILTSLEKQAKDHGGTVLYEKVDITDAKEVEALISRQEVARGKRLDGIIHFAGIIQEELLADMTSVSLHDMYEAKVYGTIALHEAASKRQNVLF
LSSSSARTLKGGMTVGAYCAANEFVEQFAHYQKLTSTVKPYCFSFSMWDEIGMSEGSMIKGILQERGYLPISKQVGFQTMLACLMTDAPLMYMGLDRSKK
EIEEMV--HAEIQKEQAIYVFFKTDQTKAIEERLYHSIHTCLQSRLSGEYSVHLYPEECWKETEDGMPDEAFFNELIEESGQNSEDRAPQTETEKLLAHI
WSELLDVSNISCGDHFFLLGGHSLKATQMLSAVRQRTGFDVPLAVLFEHTRLGELADWIDSHAKADEAILIR
>tr|A0A0Q9ISG2|A0A0Q9ISG2_9BACI Non-ribosomal peptide synthetase OS=Bacillus sp. Root920 GN=ASE42_00680 PE=4 SV=1
QEGEFDEIIKELDIRLENEHTLPDWSLQKKWTPAPLHEAEKQTEGNMVIFADTLGLADQLRSLSSNEQTYITVEPGQAFTQLTHTHFIIHPNRPSDYEQL
FETLRSYGVSVKQIIHLWNYTTQEDTLHAALAKEAQKTGSMSALYVTKAVAAYDEPVEITFVSANAMNLPEDQTHDVEKATTAGLMTAVQHEWPFIKVRC
LDFSLTETDAGRSHASSIMTELTHDTSHHIAAYREGVRYTPLLTPLHLEKEQRMKKPPFESSGLYVMTGGLGGIGRMLSEYLLTSYQAHLVLVGKKAREA
LSEEQQDVLISLENQAEKHGGTVLYEKVDITDAQAIEALISREETALGKRLHGVIHFAGIIQEELLRDMTSVSLDAMYEAKVYGTIALHEAASKRQNVLF
LSSSSARTLKGGMTVGAYCAANEFVEQFAHYQRLTSTVKPYCFSFSMWDETGMSEGSMIKGMLKERGYLPIPKRAGIQTMLACMMTEVPLIYIGLDRSKQ
EIQEMI--QGETQTEQVIYVFFKTDQTKAVEERLYQSIYTCIQSRLSGEYFVHLYPEEYWKETEDGMPDEVHFNELIEESGHASEDRAPQTETEKLLAHI
WSELLDVSNISCGDHFFLLGGHSLKATQMLSAVRQKTGFDVPLAVLFEHTRLGELAEWIDSHAKADEAILIR
>tr|A0A0P7G794|A0A0P7G794_9BACI Non-ribosomal peptide synthetase OS=Bacillus sp. NH7I_1 GN=AKG37_14140 PE=4 SV=1
QEGEFDEIIKELDIRLENEHTLPDWNYQKKWIPAPLHEAEKRTAGDIVVFADTLGLADQLRSLSADEQTYITVEPGQAFTQLTHTHFIIHPNRPSDYEQL
FETLRSYGVSVKQIIHLWNYTAQEDTLHAAMAKEAQRTGSMSALYVTKAIAAYEEPVEITFVSAHAMNVLEDQTHHVEKATTAGLMTAVQHEWPFIKVRC
LDFSLTESDAAHYHALSIMTELTHDTSQHIAAYREGVRYIPFLSPLHLEKEQRMKKPPFESSELYVMTGGLGGIGRMLSEHLLSSYQTHLVLLGRKARET
LSAEQQDVLNSLEKQAEKHGGTVLYEAVDITDAKAIEALISKQEVSLGKRLHGVIHFAGMIQEELLRDMTSVSLHAMYEAKVYGTIALHEAASKRQNVLF
LSSSSARTLKGGMTVGAYCAANEFVEQFAHYQRLTSTVKPYCFSFSMWDEIGMSEGSMIKGMLKERGYLPIPKRAGIQTILACLMTDASLIYMGLDRSKQ
EIQAML--HAEIQAEQAVYVFFKTDQTKAIEERLYQSIYTCLQSRLSGEYTLHLYPEEYWQETEDGMPDETYFNELIEESGHDSEDRVPQTETEKLLAHI
WSELLEVSNISCGDHFFLLGGHSLKATQMLSAVRKRTGFDVPLAVLFEHTRLGELADWIDSHAKADEAIPMR
>tr|B4AIW9|B4AIW9_BACPA Linear gramicidin synthetase subunit D OS=Bacillus pumilus (strain ATCC 7061 / DSM 27 / JCM 2508 / NBRC 12092 / NCIMB 9369 / NC
QEGEFDEIIKELDIRLENEHTLPDWSYQKKWTPAPLHETEKQTEGDMVIFADELGLADQLKFLSNQEQTYITVEPGQAFTQLTPTHFIIHPNRPSDYEQL
FETLRSYGVSVKQIIHLWNYTNKKDTLQAEIAKEAQKAGSMSALYVTKAIAAYEEAVEMTFVSAHAMNLPEDKVHHVEKATTAGLMTAVQHEWPFIKVRC
LDFSLTESV-GHSHVSAIMTELIHGTSQHVAAYREGVRYIPLIAPLHLEREQKRKKPPFESSGLYVMTGGLGGIGRMLSEHLLTSYHAHLVLLGRKAREA
LSAEQQDVLTSLEKQAEKRGGTVHYEEVDLTDAKALEALISRQEVAHGKRLHGVIHFAGIIQEELLADMSSASLHAMYEAKVYGTIALHEAASKRQNVLF
LSSSSARTLKGGMTVGAYCAANEFVEQFAHYQRLTSTVKPYCFSFSMWDEIGMSEGSMIKGMLKERGYLPIPKRAGLQTMLACLMTDAPLIYMGLDRSKQ
DIQEMLHA--KSRTEKAVYVFFKTDKTKAIEERLYQSIYTSLQSHISGEYSVHLFPEEYWKESEDGMPDEPYFKALIEESGQEAEDRAPQTETEKLLASI
WSELLDVSNVSCGDHFFLLGGHSLKATQMLSAVRQKMGFDVPLAVLFEHTRLGELAAWIDSHAKVDEAVQVR
>tr|N0D686|N0D686_9ACTN Uncharacterized protein OS=Streptomyces fulvissimus DSM 40593 GN=SFUL_6816 PE=4 SV=1
RDGLFTDRTAGQDGDERRRAALPGVAYSRVWTADVLLPGTPELLGALLAPARPVGTYADLSGFLGSGDRVVWVPGG--EVRLVPLTAEVDPGSPEAYAQL
GAALRRAGIESLEIAHLWALGPRAESEETGDILGAQARGVFSVQNLLRELPA--AGVAITYAAVFTRDALGGLPPGYASAPLAGFVRSEGHALTHI----
-DLSGR----YDDLAALFAYEAAQPLDGRSVVLVDGLRHKQAVEPLTLPATG---TTLDGQDGFLVVTGGLGGIGRILVALLLRRFRRNVLVLGRREAPA
VRD----RVAAFESIAREHGGAFTYAQSDLQDPALLRETIRQHAASSGQPLHGVFHLAGMVHEALVADQSTEELTEVFKPKVAGLHHLGGLLAQEHDAFL
VTFASARSLAPGATVSAYVAASDFAGHYSAHLR-SQGIRATSVAWGVWDETGMSENLRVNRALHRRGIETIEPLQGLGALLDALRTDRPAVHIGVDGSRL
PHGLAVGDQDGEPQPTCVVTDFG------DFERLFVAVEDAVRGHLGGSR-LRYEILDELPVDRNGLVDRDMVLDRLDVLRGAVTVEPPRNATEERIRDI
CRAVFRVGTIGVTENLFDLGADSIATIQLLARLRDDGVAVVSHEEFYKEPTVRHLAEQAAAGPDVPAAVVPR
>tr|A0A0F7FZN4|A0A0F7FZN4_9ACTN Nonribosomal peptide synthetase OS=Streptomyces xiamenensis GN=SXIM_47760 PE=4 SV=1
RDGEFADRAVGESGGGRARAALPGVVDVRVWTSEVLLPGTRDLLTALTAVPAPIGAYRDVGRFAADPADVVWAAPGAD----SVLVTEVDPRDEEAYRSL
ASTLRAAGADTVAVAHLWAMDTGG-DDGHRDVLDAQDRGVFSLQHLWRLLPE--AGVTLTRTTVVTRAALGPLDPGYRAAAVSAFVRGEGHTAVHI----
-DLSGT----GGDVVEVVRREETTAADGTSVAYVDGVRHLQGLEALPLPEGP---SPLALRDGFVVVTGGLGGIGRLLTAFLLRHFGRDVLVLGRRDPER
AER----EIAELRALAREHGGAFTYRRCDLGDASALRAAVEGHAASSGLPLQGVFHLAGVIHEALIAEQSVADLRAVYAPKVRALHLLGELLLERHDAFL
VAFASARSLAPGTTVSGYVSASDFAAHHAAHLR-SRGLAATSVAWGVWEETGMSRNLRVNRSLSRRGIGTMDPLRALLALSRAVGTDASGVHLGVDGARL
PSSLPVREDRPDLDDVCVITDFA------TFEEAFAEIAAALRPDH-GDRPPRYALLDEVPLDRNGAVDRSAVLSRLDVLRGEVTVEGPRGPLEERIRDI
CRAVFRVDTIGVTENLFDVGADSIATIQLLARLRDENVVQVSHQAFYAEPTIRHLAEQAAAAEHRAGEPAPP
>tr|A0A0N7CPA4|A0A0N7CPA4_9ACTN Nonribosomal peptide synthetase 1 OS=Streptomyces sp. M10 GN=vlm1 PE=4 SV=1
RDGLFSDRTAGQDGEERNRAAVRGVAGSRVWTADVLLPGVPDLLEALLAPARPVGVYADLTGFLGSADRVVWVPGGGGTVRLV-LTAEVDPGSPEAYAQL
AQALRGAGVDSLEIAHLWALGAP----GDGDILGAQSRGVFSVQNLLRELPA--AGVTLTYATVFTRDALGVLPPGYGSAPLAGFVRSEGHALTHI----
-DLSGP----GGDLAALHEIEAAQPYDGLSTLYVDGLRHRQAVEPLALPATG---ASLDGEDGFLVVTGGFGGIGRMLVALLLRRFRRNVLVLGRRDASA
VRD----RISEFEAIAREHGGVFAYARSDLQDAAQLRETVRDHATTSGLPLGGIFHLAGMVHEALVGEQSTEELTEVFRPKVAGLHLLGELLVWEHDAFL
TTFASARSLAPGATVSAYVAASDFAGHYSAHLR-ARGVRATSVAWGVWDETGMSRNLKVNRALHRRGIETVEPLQALGALLGALRTDRPSLYIGVDGSRL
PQGLAVEEPV--HETACVVTDFS------EFERLFAAVESAVRERVGGTRPVRYAILDELPVDRNGQVDRDMVLDRLDVLRGAVTVEEPRNATEERIRDI
CRTVFRVGTIGVTENLFDLGADSIATIQLLAKLRDDGVAVVSHEEFYREPTIRHLASQAAPEPGTPDALPAT
>tr|H8MSA9|H8MSA9_CORCM Putative non-ribosomal peptide synthetase OS=Corallococcus coralloides (strain ATCC 25202 / DSM 2259 / NBRC 100086 / M2) GN=pks
EKGLLVPAWQRGRKNTAAPEVLNGSVYRRNWVPHGLTPVQA-LPDTVVVFAPAGEPGKRLTAALATGQRVLVVEPGTGFALNGGDRLTVLPGDAGDAARL
VEHLA-DTAAGAPLIYAWPLAGRSGTESFDATEAL-LALLPPL---ARRFG---KNHPRLLAVTHGAATGELL-GDPKAAMIGALLRVVREET-RAAVRA
VDIDSL----E-AFAEVVLGELTDPSGEVECAYRRGLRRVSRLEPVRLQEQ----GGTLRQGKRYVVIGGLGGIGRALVRYLVTAFGARVAILGRRAERA
LDPASAA---ALTGLRQL--GAVTYGAGDVSDGDGLRGALARASESLGGTPDGVFHLAGGFFEQPLEQLELGKALGGMIAKVSGSREVVEAAEALGIPWV
ALFSSVNGYFGGPGLATYAAANRFQEALAGSWNG-KRTRVCTLAWSMWDETGLSRGYANKELTRERGFVVFSPDAALQLLDSALSQAQDTLFIGLDATRP
RMRVEL-DMSPEPLT--CLTARTSAEP--R-------AIHALGDAFGIELTVRPRSSTAAPAKAAGVEAL------------AARTATDPAAIAEQLTAL
WCDVLKLEELAHDANVFDLGAHSLLLPNMQGRIRESFGVEPTVVDLFQYPTVAKLTAYLASR----------
>tr|A0A093SZ49|A0A093SZ49_9ENTR Uncharacterized protein OS=Pectobacterium betavasculorum GN=KP22_16090 PE=4 SV=1
ADASIKPLWESTP------NRLVNQIFRRLWQPLAISETSL-PVQRILMFCAETCNLADVEKAFAGTDQLRIQDSSSQFEWTEAI---------------
QAQLN-SQQPVSHIIYIAD----SD--ELTIAEQA-TSLLAPLLALLQTWE---KALPLTVVTLHGQYHTDQP-VNPVNSLVTSLVRSAREEIPRLSCRV
VDMTDI----SQMTVEDLLTEIRSSAQDSEIAWRDGLRYVSRLARLKISGN----GADSSINPKYVLIGGLGGAGSILAERLAQNADAHIWLIGRTPVEN
MNAESLM---RLARLKKVS-THVHYRVADVADYPNIAEIIAQIQAAEGGNIGRIYQLAGSFRQWQIKEINPAEDFALLDSKVQGSSNLYTIAKEFSVPSL
VFCSSANGYLSGAGVALYAVANRYQEALAELAQQEAQLHVTSAGWSMLEDTGLSQGYVHKALTEAKGYIVADPHQAIALLDPVIASGEHACVVGLNPDAP
AMAGEF-WFKPMADV--AADSAESC----------------------------------------ANQAE------------ETAGDNSADAVAEKIATI
WQELLDLDELGWDENLFDLGANSLLLPQVILRIERELGFRPALVDLFQYPDVASLAEFVSDN----------
>tr|U5WXG6|U5WXG6_MYCKA Uncharacterized protein OS=Mycobacterium kansasii ATCC 12478 GN=MKAN_02195 PE=4 SV=1
LGCAPGADI--R------PEV--------LCTPTLESATPG-PALPVLLLSDREEFTAALAQALRS---RGHALSTSAFELTDAQERRRIR---------
--SLL-DGGP-EHVVHVLPVGPPTP--EV---AGR-CADLAALLRVMEQTG---GSV---VA---------PT-GCEYGQSLAAFAHSAGRDLPRLKVRF
IGSAVS----PEAVADELSR-----EEPAEVDLGLPVRRILAAAPIRAAGE-----SALQRAGRYLVIGGLGGVGRHVCEYLLRQFGAHLLVVGTSELDC
TQPAGPRG-RNLLALREM--GDVTYLAVDVADAMALRAAVEVFEQQHGGPIDGMFALAGELVPRSAVQLSAADIDDMLYAKGRGAIAVERLLAERAHAIE
VYFTSVHSLVGAPELAAYAAANRFQDVLAARHRD-RGRRAWSIAWSRWAGPGMSLDVAGGDLAAEMGLATIDPAVGIDALDAVLRSRPGWYAVGLDTGNR
RLAHLAGGLRPLERI--EVRMA-GPAT--D-------VTAAVTDAFGVPVPAHVVGQQ-----PAGPPAP------------A--AAGDQGSAMAVLAGI
WAELLKLPDVSAADDFFELGGHSLLVPRLQERVLQLLGVALPAVAVFEYPTLRELARVIEDR----------
>tr|K0ETZ1|K0ETZ1_9NOCA Linear gramicidin synthetase subunit d OS=Nocardia brasiliensis ATCC 700358 GN=O3I_015030 PE=4 SV=1
ADGELAARVVD--GVGGASGTTPDCVYVTRWRPVPPSPRHATLRGPIVLFADASGVAAEFT---RQLPDYLLVRQGTDFRR-TEDGFVIDPDLDQHWAAV
RAAL----GTPQTVVYLWSLAAETD---------------KHLVSAIQCCT---HDLRLITVSRGAHVTGTES-GIVAAAATAAVTAVYRQEYPGSEAVH
IDLAESA---PERTARDLAIALDHSTAYPEVAWRQGRPYLPALTRVDAPVTV---PSPLRTDGRYVVLGGAGGIGTELVRDLAATLRARFLIVGRRALDG
PN-NTALQ-DNWRKLRDAG-AQVEYAAVDLRDESAVRAAVTAAENRWGAPLDGVIQLAGEYRLRTLRAEQPADWDLTATGHLRGLLVAAALVRERPSSQL
ILGSSLMGEFPAAGCAAYAATNALSRALTAELRRRDGMPITRLAWSLWRATGVNAGNRYEAAAAARGFLALRPDDAVRLTVETLCRPPGDYQIGIDRRGT
DVRALVDDTRDLAL--------T--------------------EPAGTAPPADLAPVA-----AA-TL--GHM------IRA------------------
LDG-FTGLPLSAHTPLSALGRTSVQMVQVHARLEGALDTAIPHEMFFAAPTLGALAGALHES----------
>tr|W5WF89|W5WF89_9PSEU Uncharacterized protein OS=Kutzneria albida DSM 43870 GN=KALB_6152 PE=4 SV=1
RNGAFDEVLSEIEGAPEPE-ALPNWFFDRAWLPAEQEARAELPTGPWLLL-APDGAQIPA------EDNVII-VRQHEFD---GD-----------YLTL
VER-----HKPSVVLHGFGLARGEG----DQL----HTGVYSVRGAL--LA---G-VQLLVLTQGGSWREGDR-VDVAKAALPGLIRTAAAERVLPVVRQ
IDVDGG------DLLAVVRAELAARGQNDLVSYRDCQRLVPRLRPVAVGDDL---PPNVRVGGLYLLTGGLGGIGYEVAQYLLAAYQAKLLLVGRSEV--
----GPED-ERLADLQAL--GEVEYRSLDVADSAALAAAVTEAERAHG-PLTGVLHLASADVQHTVAREPLSAFSGIYQAKVFGTLALAELLEDRPEAVL
VLFSSVNGDFGGSSFGAYSSANSFLNGFADHWGRERGRPVRCLAWSMWAGVGMNQGSPTA-AAASRGFRAITDEQGLESLLFALATEHVHLLIGLDGRNE
HIVRELAPEQLRNSE--IVLAHTGPEI--DPA---ALS----EVVRRSPLPVRILAVREIPRDAEGGVDQARLLAAVDRPSGGHRHVEPATELERKLAEL
WAEVLGQQRIGREDRFFDLGGSSLRAAQLIARTNSALGTRLLVHQLYEHPTIGELAPVLAKE----------
>tr|T2S2F2|T2S2F2_SACER Peptide synthetase OS=Saccharopolyspora erythraea D GN=N599_07620 PE=4 SV=1
RAGKFADALRALEGGPVEEPSEDNWFFERVWTAQSIVESES-RAGVRVLFADVEREQWLG------EHDVVV-LPGTRFARD-GNRFSIDDANPAHYREL
LTAVRSDFGRIDAVVHAWAAT-PGG----AGL----RSGALSVRMLL--LA---SWPEVLVLTTGGVRGDGDA-VDVAKGALPGLVRTAVAEGAVPVLRQ
VDLPAAT---PERWAAIVRAELDAVPDADVVAHRGGTRLVPRLRPVEPEAGS---SPALVQGGVYAITGGLGGIAQQIAEYLLAAYQARLLLIGRSPVAE
G---TPKA-ERLADLRTL--GEVEYRALDVGDTAALHSAVAQAERRWGRSLDGVLHLASNDVEHTVARASRGEFARTYRAKVHGTMAIAEVLRDRPDTLL
VLFSSVNAEFGGSSFGAYSSANSFLNGFADHWGHELGRPVRCLSWSMWTGSGMNRGSPSA-AAASRGFVPIDDASGLSSLLTALGQDRVNLLIGLDGRNE
DIIAELAPEHSRSTE--IVVAYSGAGV--DEA---ELREATAELVARCEAPVRFSRVDRVPRDAAGRVDQAGLLAAAASAGERRRYAEPETDLERRLAAI
WGEVLGRERVGRDDAFFELGGNSLRAAQLVARINGTLPARMAVHQLYDHPTVGRLAEVLDKA----------
>tr|B4XY94|B4XY94_STREG Azi1 OS=Streptomyces sahachiroi GN=azi1 PE=4 SV=1
REGLFDDRCYG---GG-TDAPDEAPDSEASVPALAVVWEPADPDGPLVACVSGDVPDWLP------VSTAQIVV-GP------D-AV--ELASA--LERA
FATAGEDEGAVPQVLFVAASDPATA----GDA----GVLSEFLA-V---VA---RIAELTVLTRGAVPAPGDT-VVPGRTGLTALVRTARSERLLARTAL
IDAPADA---GA---AELAALATVRHSGDVIAVRDGRPLQQRLRAVPLPEVFDVPADVLPRGGTCLITGGLGGLGRAVAEHLVVTHGARLLIVGRTPQER
LD--TGAR-EALEVLHAI--GEVRYRTADAADPDALAGAVAEAEASWGCGLDLVLHLAGAAVDHELRAESAQWLATMLHPKAGGCAALDGVLATRPDTAV
VLYSSVNGLFGGTGFGAYAAANAVLDGWAQRWAA-AGRRAQSLAWSMWDGPGMNQGSPLVAAGRHRGLTLIDPTRGTLALLGALHAGPVHLLIGADPANE
QIKPLLAADQLGGGT--VAVAVVPADT--DPQ---QVRAAVSAQLADRGIFARVVVTSRIERDRSGTPDPAAVLAAGAGGAS---YLPPEGRLEALLAEA
AAEVLGVARVGRDDSFFSLGCDSIRAVQLAEALSGQLDSPVSVGSLYESPTVRSLAARIAG-----------
>tr|S5TV27|S5TV27_9BACT Long-chain-fatty-acid--CoA ligase OS=uncultured bacterium esnapd17 PE=4 SV=1
QAGRLQAYTDE---SA-EDAPTEAWLLERVYAPAPVVPAPLDADDPLAGVLAQRFPATVI------VD--QECR-GT------DDGVALDLRDAEQHRRA
LS---YLESVPARVIYCLAASP--A----DLD----GPATELLL-A---LA---EAADVTVLTRHALRDERDL-VDPARATLPALVRTAQAEGTVGAIRL
LDVPVDV---DA---ADILAAGQ-PAGTEIAAVRDGTAYVERLRVVEEPPGLAIPADLLRPGGTVLLTGGLGGLGAQVAQYLLAAVSARLLVVGRTPEAQ
LT--PARA-AVLEELRDL--GEVDYVALDVADAGALRDAVAKAEQRWDAPLDVVLHLAGVDVAHTLANEQPAWLADMLAPKLGGARAIDSLLAERPDTSV
VLFSSVNGFFGGSSFGAYAAANAGLDGYALRWAA-QGRTARSLAWSMWTDTGMNQGSPLTAAAEHRGLRAIDASRGLALLLATLNQDRPYLLVGADPDHD
AIRPLLADDQLDGAE--IVVAVVGDAA--AQA---AVSHVP-------G--VRVVGVQEIPRHADGR---LNVKALGPARRA---YDPPEGELETAIAEI
LAEVVKQERVGRDDSFFTLGGDSLRAMQVVGRLKERLREPVPVSLLYEHPSPRELAAALSG-----------
>tr|A8CF88|A8CF88_9PSEU KtzG OS=Kutzneria sp. 744 GN=ktzG PE=4 SV=1
RAGRFDDRVI---TVAAP--PADTRLVTREWTELPSSPAADDETGVRLVLGDDSDRERLG------IDTVVSVRRGDGFGQDAPGRYQVAPGDRGQLRSL
LRAVTERHGRIASVVHAFPLARGGE----RLL----AITTELTALL---T-----EVRLLVLTAGALWRDGDS-VDLGACALPGLIRTAVSEHPTMRVRQ
LDLPAD----DGEWAQAVRRELADRNHAGVVAARDGRRWQPKLTPLAETETET-VTAPVRTGGRYLVTGGLGGLAVEIAGHLLAAYGVRLLLVGRSTVD-
----GAKA-DRLAELSAL--GDVDYVQADVADAGALEAAVASAEARWGHGLDGVLHLAAADPRHTLANEAAATFAEQYRPKVSGTLAVAAVLDRRPDASL
VLFGSVNGEFGGNSFGAYAAASCFLVGFAEYWRHERRRSVKCLAWSMWTDVGVNAGRPVE-AARRRGFRAIDPDAGLRLFLDAMAAPGHYLLLGLDLANP
TIVADLGPGGVHAGE--LLVAYAPDGV--DPG---VVRAAIAAGIRDAVVPVRLVALPRIPRGVDGSVDTERLLLDAPGRRRRT-PAAPRSDLEREIAGV
WSAALGRTAIGRDDSFFELGGNSLRATRLLALVDDRLGVRVSTQELYESPTVAGMAAAVRER----------
>tr|A0A0M3U7F4|A0A0M3U7F4_9PSEU Uncharacterized protein OS=Pseudonocardia sp. EC080625-04 GN=FRP1_29800 PE=4 SV=1
REGRFDDRVE---TGGL---PEAAWTLSRRWTVLPDVSATDDSRGAVVVLADGD-VPVDD------GRTVVAVS----------------RGDTESVSAA
LTGVARRYGSIDSVVLAWTLPNQSR-----------EAAEEYTAMFLSATA---AAASLLVLTQGAVHVDGDH-VDLGAGVLTGLVRTAGAESPVVLTRL
VDLPEN----RSEWGRALTIELGDRETAGVVAVRDGVRWVRRLRPLSGDDPE--GSSPLTAGGLYVLTGGLGGLGYELASYLLGAYNAKVLLLGRSPAE-
----GERA-ERLRELHEL--GEVGYHAVDIADTGAVVDAVREAEQRWDRTTDVVLHLAGADPRHTLLTEQQATFDYFYRAKVAGTVTVGHLLEDRPQAKA
VLFGSVNGEFGGNSFGAYSAANSFLTAFADHWHHERGRDVRCLAWSMWAKVGMNAGQATG-AVEQRGFRVIHPDEGLETLVEVLRSGHRQLVIGIDTTNP
QIIPEMDGDVLGANE--LVVAWTGADC--DPV---AVERAVADAGRTCPVPVRPVRLAKLPVTVHGAVDVAQLLLDAATACDGGEVVEPIDPLEVRVAAV
WSEILNRARVGRDQSFFDLGGSSLRASQLLSALDDRLSVRVRTQELYENPTVAGLAEVLEQR----------
>tr|D6A434|D6A434_9ACTN AMP-dependent synthetase and ligase OS=Streptomyces ghanaensis ATCC 14672 GN=SSFG_06825 PE=4 SV=1
QAGAFDHELAELSAAGHDHDEPASWLFTTKWVRATADPGPA-GSGVWLVFGEGDLAARLRA--ARPDGPVVPVTTGTTFLRDA-GSYRVDPLDPAHHAEL
LAAVRREHGTPGALVHAWATGAGSA----GTR----GPDLP--AGSLHSL-----GLPLYVVTNGAL-TPDDP-VEPVHATVNGLVRTANAEGGAPWVRQ
LDLRPDD---P-DPAASVLAELGDRGADEVVARRDGRRLVPRLTPLHEAAPD--ATHRIRPGGLYLLTGGLGQIGVRLARFLLTEHGVRLVLTGRTAPT-
----GDRA-GRLAELAGL--GDVVHHQADVTDLDAMRAAVAGAEQRFGQELDGLVHLAGAGFAHLLTAEDAAEFRRMFQAKVTGTEVVAEVLRDRPDALL
VLFSSVNGHFGGTAFGAYSSASGFLPAFAAHWRR-LGRPVQCQSWSRWTTDQ-DGGVGLE-ALRRHGYREIDPEHGVRLFRTALADPAEHVLIGLDDRNE
HIARELDPAFLGPLQ--VTVSYHGQPG--DR-----VRQ---------------AVVSAVGSGVAVRV--EPAQ-----AAQGGDGPEPVGELEHAVAEI
WRAALRSTSLNSTDHFFEQGGNSLTAMRLVDRLNVAFDVQLTVQHLYDHPTVEKLAREIERL----------
>tr|G0LWA4|G0LWA4_9ACTN Non-ribosomal peptide synthetase OS=Streptomyces himastatinicus ATCC 53653 GN=hmtK PE=4 SV=1
RAGAFAGRTI---GAA-PD-GEDPWVFRRQWTEIPAAPDAPDGTGVRLVIAEEEDRARLR------VDPLVAVDRGGEPTRRAPGHYAARTHDRGELRRM
LAAVTADHGPIGTVVLAPPLSGGAD----RLA----AATAELSALV---AD---GEPLLLLVTAGAQYRDGDT-VDLGTCALPALVRTAAAENPRLVIRQ
LDLPAE----ADAWPAALSAELADRDRTGVVAVRDGRRRQPRLAPVERDGAD--PAPPLLAGGLYLVTGGLGGIGHDIAGYLTAAYGARLLLVGRSPAD-
----GEKA-ARLAELTAL--GEVVYRQLDVTDAAALEAAVTDAETRWGRPLDGALHLAGADPRHTVANESGEVFAAQYGAKVAGTLAVAEVLATRPDASL
VLFGSVNGEFGGHSFGAYSAANGFLAGFADHWHHERRRAVHCLAWSMWSGIGMNRDQPAA-PAHSRGFRSIDAPDGLRLFLEAISVPHHYQVVGLDAANP
AVMDELVPEQLRTGE--VLVAYTADDI--DPE---TVRAAVAPSTRDRPVPVRLVRVDHLPRDAAGRVDTARLLAEAVGKPGRRTVTPPADDLERRVAAL
WSEALNCPEVGRDDSFFDLGGNSVRATRLLALVDDAFAVRVPTQRLYENPTVQAMAAVVAEA----------
>tr|A0A0M9YD45|A0A0M9YD45_9ACTN Uncharacterized protein OS=Streptomyces sp. WM4235 GN=ADK55_30005 PE=4 SV=1
RSGVFDGRAI---GADEPE-PADAWLFERRWGPAPAAAPAPRADGVRVVLAEDTDLTRLA------VDSVVTVRRGAGPVREAPGRYVAALDDRDALRLL
LATVAADHGPVGTVILTLPPEPDGD----RLA----RATAEFAALA---AD---GAAGLLVLTSGSVHQDGDT-VDLGTCALPALVRTAADEDPGRPIRL
ADLPATD---PGAWPAAVRGELADRDRRGVVAVRGGTRLRPLLAPVAPGPAADRAPGLPSAGGRYLVTGGLGGIAHDVAGYLVAAHGARLLLVGRSPAD-
----GERA-DRLAALRAL--GDVEYRQLDVADTAALTAAIAAAEARWGRGLDGVLHLAGADPRHTVARETPEGFAAHYRAKVAGTLAVADVLETRPDAHL
VLFGSVNGEFGGHSFGAYSAANAFLAGFADHWHHERHRPVHCLSWSMWTGTGMNRGRSAA-AAVSRGFRVIDPADGLQLFLDAVASPHHRLAVGPDPSNP
AVMDELVPDRLRAGE--AVVAYTAEGV--APE---TVRAAAAAGLRRCPVPIRLVEVTAVPKRADGNVDTAALLRDAPGRPRRA-FTAPVGEREEKLAAL
WSQALDGARVGRDTSFFDLGGNSIRATRLLALVEDAFAVRVGTQELYEHPTLAAMAEAIGRR----------
>tr|F8C9S6|F8C9S6_MYXFH Putative non-ribosomal peptide synthetase OS=Myxococcus fulvus (strain ATCC BAA-855 / HW-1) GN=LILAB_00720 PE=4 SV=1
EAGELVAEHHRALSILGGPATMPPCLAVARWVPRPLASSVSKTQGAVVVIADEAFAGAMRE----QMR-REVV--------------RVAPEASGDLVHV
LGALAERGLPCGDVVVRLPDVGGEAPADAEARRVVLAASVAPLLRALQA------AVRVLAVLPETGTGTHGA-GTQAALLAPGLLWAAAAEVPGLEARV
TWAPSDA---S-AAAHAAAREVTSQDAAREVAWRDGTRWERLFTPWTPPPLA--APQRLKREGLYLVTGALGGLGREWARQLRQGVDARLLLVGRRAHGP
E----------ARALEAEL-GAAKYLSVDVTDEAALREAVRHAEAHFGQPCDGAFHFAGTLTPTPVADETPESFVQGAAAHALGALSIAAVLEGRPQAVC
VFAASLMGTLGAGRHAAYCAGTAFLERLAERLTA-QGRHAAAVSLSQVRETGLARALGT----APPGYRVLEPSQALASVALAGEHAPAHLLVGVVASAW
PWRQAGLGSGRYLDA--AHVFLVPP-P-------------R---PEGLS-GAVLHPLTEWPRRADSSVDREALAAD-LSGTG---DGTPAGPFETVVMEA
FREVLGAQGVGAGSDFFTLGGSSLQATRVVARINERTGLRLREVALFEHPTATALADHVRRV----------
>tr|Q1DBW8|Q1DBW8_MYXXD Putative non-ribosomal peptide synthetase OS=Myxococcus xanthus (strain DK 1622) GN=MXAN_1603 PE=4 SV=1
EAGELGAEYHRSLSVLGGPATMPPCLAVSRWVPRPLATRV-GTRGAVVVIADEAFAGALRE----QAD-YEVV--------------RVAPEASGELVRA
IEALAERSVPCGDVVVLLPEAQEVPAVSDAVPQAAVASRMAPLLHALQSRG---EGVRVLAVLPESGGD--DA-ASLAALLTPGLLWTAAAEVPGLEARV
AWTPPDA---S-ATAHAVARELASQDAAREVAWREGTRWERVFTPWTPPPLA--APQRLKRGGLYLVTGALGGLGREWARQLRQGLDARLLLVGRRPHGP
E----------ARALESEL-GTAKYVSVDVTNEVALRNAVRDAEAHFGQSLDGAFHFAGTLTPVALEHETPETLVQGAAAHALGARAIATVLKDRPQAVC
VFAASLMGTLGAGRHAAYCAGTAFLERFAERLTA-QGRHAVAVSLSQVRETGLARSLGA----APPGYRVLEPSQALASVALAVEHMPAHLLSGVVGAAW
PWRQAGLGEGQGLDA--AHVFLVQR-P--G--------DVP---PEGLS-DAVLHSLPEWPCRADGAVDREALAAD-LSGAG---DGAAAGPFETVVMDA
FHEVLGAQGVGVGSDFFTLGGSSLQATRVVARINERTGLQLREVALFEHPTATALAEHVRRV----------
>tr|A0A084SW96|A0A084SW96_9DELT Peptide synthetase OS=Cystobacter violaceus Cb vi76 GN=Q664_14145 PE=4 SV=1
ESGELADERREAERVLGGPATLPRCLAVPRLVPRPQVPAGVSLSETVLLFSPSGFATALKE----TISPVEWV--------------ALAPD--ANPLHT
LETLEAQSLRFEDVVYVMGR-------ASRAGSAELARSISPLLRLVQGRA---AAVRLWVVAPRAEGSSF----DAAPLLVPGLLWSAKADAPNLSVRL
LWVPSET---P-DAAAFVAGELQGLRSAREVSFHDGQRWERGFTPWVPSRLE--GAQRLRREGLYLVTGALGGIGQAWARHLKHSLGARLVLVGRRARDA
A----------AEALEREL-GA-TYAQVDVTDSARLRAVLDEAESRHGRPFDGVFHFAGNFEPVPLEAEAPETFIQHAAAHVLGALALAEAFQPRPEALL
FFASSVMGTVGWY-ATSYCAATGFIDRFVEHLAA-RGRRAVAVSLGPVKATGMARTLRA----SPVGSRTLEPQQVLAALVLALESGRTHVLVGVDGSAP
AWRTAGLGAGEPLEQ--AHVFFTQASP--G--------VLP---VKGEPGVTALHPRPAFPRRPDGQVDAEALAA---ESFG---EGVPTGPLEEMLVEA
FREVLGVEAVGTHSDFFSLGGSSLQATRVMARIQERLGLRLRESVLFDQPSVSRLAAHLQEL----------
>tr|D7BUR9|D7BUR9_STRBB AMP-dependent synthetase and ligase OS=Streptomyces bingchenggensis (strain BCW-1) GN=SBI_00139 PE=4 SV=1
TAGSFDERLRRLEVVEEGPRTVPPWFFAPVWEEAPLRGAAPPAPNPLVVFADDHQDGLLTGATAARMPPVIVVRPGPYGLREQADGYRLDPEDEAGYRAL
LTAIAREHPQVDGIVHAWSLAGDA---VPGGL----RRGALSVARLV--AD---SPAALLVATRLPVAAPTAA-GSLANGALTGLVRSVATERGEGVTRL
IDVADNA---GRALITAIRAELAS-SGETLTRYAAGRRLAARLQPIAAPALSR-PGEAFHEGALYAITGGSGGIGQEIAHHLAAAYGAKVLLLGRRDAAE
T-----PA-PSPLPPEGK--GEIRYERADVTDPDALGDAVARAEQTWRQPLAGVLHLAGRSLAHVVAREPSEEYEQTLAPKTAGTLAAAHLLDDRPDACL
LLFSSVNGYFGGTGFGAYAAASSFQDAFAAYWSRSRGRDVRSLAWSQWSGVGMNADGPMTAAAAARGFRPITPAQGLGSLLLACTGAERHLLIGLDAHNP
DISPLLADTATRR-A--VLLGYTGGRA--ED------VLTAAAGVTGGGVPVHVASVPALPHTPAGEIDGTALARLAIGSGDPSRTRPPKAGLETDIARV
VCDVLGRGFIGREESFFEVGGNSLFAARLQHEVARRLERRLPLRALYRHPTVRALATALREQ----------
>tr|A0A080NS94|A0A080NS94_DELAC AMP-binding enzyme family protein OS=Delftia acidovorans GN=DR66_1988 PE=4 SV=1
ETGAFDREIKDAACLIGGAGTIPAWFARPVWRPRQHDALPAMAHALTALCGAGAALA-----------QLQALQPRHRWMAL-----DDTGSPADAVAA-
----L-REWAPDVLVLAGE--------------QALAP---GLLQAA-RAP---GGGRLLVCAGTAQD-------EGQRAMARAVLRSLEAEMPALRCRH
VAWGDAG---VALDAAGLCAELGCSQREPEVLWHAGVRRVRRLVPLVPLVPLVAGHQGFQEQGLYLLAGGLGGVGFLLARHLLGRYRARLLIVGRAPAVE
------RR-QPLELLSRS--GTLLYVQADVTDPAALQAAVAQAQQHFGQPLAGVVQLAAESRLALCAEEEEQCFARAQRAKVEGTRHLHALIAHDPRALF
LVAGSVMGLLGGRRVAAYAAGDAWQMAFVERQAHSGGARCRYLGFSAWRDIGLSRQVSNPALFAASGYLSIDEAQGLQAFELAVRGEQPVMTVGLDLGHP
RHAAVREGAIYGADE--LVWVREGAVD--ARRAGPSAPHRWLHDACGRPVSVPVLNVASLPTDARGELDRAALLR---LAAGMASSAAPRNAFERYMVRL
WCKALGLADCGVDDDFFSLGGNSLGAAQIAARTRELFRVDISMAELLRHPCMADFCQRVIAL----------
>tr|J2USJ4|J2USJ4_9BURK Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II OS=Herbaspirillum sp. CF444 GN=PMI16_00407 PE=4 SV=1
EAGVFDAEIKQAACLLEAAGTIPHWFSEPFWKACPIAVTAGEVHGQSAVLGDASGDAAIR--------ALARAAGDIDWRQFV---LEEQPDPLPSLGRL
FNAMA-QQGLPDVILILPG--------------WARLP---RLLSLCQATA---RGVRLIVCGGADAA-------E--HAAAAAFLRTAAAEIDGVHCMH
IQFSGKD---LG-----ILGDLRQPTRETELAYIDGARHLRRWRNVE----LSADRPALRSGGLHLISGGLGGVGLLLARHLLDRHDAKLLIVGRTEAAQ
LD--AARA-TALRELERS--GRVLYVSADVADAAALGAAVAQARARWQCGLDGVLHLAGEGRQTELRRETAATLAQMMHAKVAGSLALQALADAHPGARL
VLVGSVAGMVAGRQDAAYAAANAWQAALAEQL-AAGNTRCHYLGFSSWRHTGMSKNGAPVSTVEAAGYFSLEPEHAVASFDIALSASRPVLAIGLDLQHP
RHAGLQDAAIAVDEA--LVVEAG-------GA---AQGAVMLRDHFGRSLPVAVLAVDAIPRNEAGGVDREQLTR---IAGGFLQLGRPDSEFERYMAQL
WKQILDLSICGVHDDFFALGGNSLRAAQIAAATRERFRLNAAMPDLLQNPTVAGFCAHVQRS----------
>tr|D6B3W6|D6B3W6_9ACTN Actinomycin synthetase II (Fragment) OS=Streptomyces albus J1074 GN=SSHG_00057 PE=4 SV=1
EAGEFDGAVRETQLLLGTAATVPDWFLHPLWRPAENLHAA-TPAGHRLVLAGPAAVAEEVAGAVRDAGLCTVVTEGPAPERNGAAAYRVRPGEAGDLAAV
LERLEADGRTPDTVVHLAATEDAE--------DGAAPGSDVSLLVLAQART---GGVDLLFVTAGAQATPEER-PTASHAAAGALLKSLREELPWLRGVH
LDLSGGS---AGDRAAAVLAEAAGFPADTEVARREGLRYVRRLAPLPDSAPRT-APAPAPADGFHLVSGGLGGVGSEVAAHLLKEPGTRLLLIGRTGLPP
EDPASSRI-EAFRRLRGL--GEVRYETADVTDAAQVRAAVRRAADAWGVPLVSVLHLAGAFDERPVRELTPQEWREALAAKVDGAWALHRVAAGHPVTSF
VTFSSVNGFFGGAMNAAYSAANAALDDLALRRRRE-GLPGQSLAWSMWRERGMSLGYQLTSLTEARGYRVLDAQAALRSFDLARTLDLPHLLIGADRTAP
WVRSHVLAPVRQVRR--TAARVVLD------------EGTDLGALYGAAARA------------AGPEGTFVLRSASSGRSEDTGGADELRRLESELAAV
WCTVLGRDRVGRDENFFDLGGNSLLLVAAQTAVNKALGCELGVVDLFSRPTVRALARHLSQQ----------
>tr|A0A060Q371|A0A060Q371_9NOCA Putative non-ribosomal peptide synthetase/polyketide synthase OS=Nocardia brasiliensis PE=4 SV=1
ADGELADRVVD--GIGGVSGTTPDCVYVTEWRSVPPSPRHVTLRGPIVLFADESGVAEEFT---RQVPSYLLVRRGATFRR-TEDGYVIDPDLDEHWAAV
RSAL----GTPQTVVYLWSIAAEID---------------KHLVSAIQCCT---HDPRLITVSRGARVIGTES-GIVAAAATAAVTAVYRQEYPGSEAVH
IDLAESA---PERTARDLAIALDHSTAYPELAWRQGRPYVPALTRVDAPITE---PRPLRANGRYLVLGGAGGIGTELVRNLAATSRAQFLILGRRALDA
PN-NTALQ-ANWRKLWDAS-AQADYAAVDLRDEAAVRAAVAAAENRWGAPLDGVIHLAGEYRLRALRAERSADWDLTAAGHIRGLLVAAALVRERPGSRL
IIGSSLMGEFPAAGCAAYAATNALSRALTAELRRRDGTPITRLAWSLWRETGVNAGNRYEAAAAARGFLALRPDDAVRLTAETLCRPPGDYQIGIDRRGT
DVRALVDDARDLAL--------T--------------------EPAGTAPQADLAPVA-----VA-TL--GHM------IRA------------------
LDG-FTGLPLSAHTPLSALGRTSVQMVQVHARLEGALDTAIPHEMFFAATTLGALAGALHES----------
>tr|A0A0E3JHU8|A0A0E3JHU8_9BACT NRPS/PKS hybrid protein OS=uncultured bacterium AB_162 PE=4 SV=1
VDGSYDEIVKRLDLVESNGRTVPECVYELGWEAVSPVAARSG--APRVVVMDGLGLGDSLSRLWPE--GVERVRPGSDGSRNPAGELVIDPSDPGGWSLM
LDSAL-DATGDNVLVYLPTYGSGAPGE-------ALDPGCSHFLALCR-AS---RATRLVVASRAARRAEPVA-EDPGMAPVAAFLMAVSAEVPGLDGCL
VDLEGGS---LDSDVQALFEICNGEWPGPELAWHDGAPHVRLLRSVVLETAD--AEPPFCDGGFYLVSGGLGGVGSELLAELQERWDLDLLVIGRTPLSA
AEGESSRR-RALEKLGSAG-GTVEYRVADVAERDQVEALVADAERRLGRSIDGALHLAGEYDGRLLADEPAGVHAAAFRSKAAGARVLGEVCAARPGSVF
VAFTSAFGHVATLGGAFYAAANRYVDAYAAHLRQVRGISAYSLSWGMWRGTGMAAGGDSEAWLERRGMIGLAPEEARHLALAALHGPPGHLIVGFDGATS
LAPARIASRRSTNLE--TVSLEVPQR----SS---GWSPPPLEDDFGRVVPVALAELQDD---RASRGDDRL---------A---TGEAADRLREVISTA
VGEVT-GTPLDEDRPFYDAGLDSLTILRIHNRIEERLGIEFERSALFEHPSVRSLAGFLTTQ----------
>tr|A0A0E3M0J9|A0A0E3M0J9_9BACT NRPS/PKS hybrid protein OS=uncultured bacterium NM_1663 PE=4 SV=1
LDGAYDDIVKRADLAAASSRTVPECAYELAWEPVSSLSARTG--EPRVVVMDDAGLGGALSSLLPG--ETERVLPGRRGSRGPGGELVFDPTDPSAWTSM
LDMAL-GASGSNLVVYLPAYGVTGPAN--GTGSESIDRRCRDLLALCR-AG---RAIRLVVATRAARSIDLVA-EDCSVASAAALLMAVSAEVAGLDGCF
VDLEGRS---IDADARALCDTCSSGWPGPELAWQAGVPYVRCFRSVTLDSAG--AEPPFRDGAFYVVSGGLGGVGSELLAELQERWHLNLLVIGRTPLSA
DGGASSRR-RAFERLGGGG-GSVEYQVADITDAARVEAIVEDAERRLGRSIDGALHLAGEYEGRLLADQPVSTGEAVFRSKAVGARVLGEICAARPGSVF
VAFTSTFGYVETLGGAHYAAANRFVDAYAAHLRLTRGVPAYSLSWGQWRGTGMAVDGAGEAWLGRRGIISLSPTEARHLAVAVLRRPPGHYIVGLDGAHS
TTPARIVSDRPTNLE--TVSVVVPAL----PA---DWTPPPLEDDFGSAVPVALAEPDEH---HASDSGERN---------LDSDVSSANARLGEVIREI
IGQVT-SQRLDDDRAFYEAGLDSITILRVHNRLEEQLGIEFERGVLFEYSTVRSLAAYLAAH----------
>tr|A0A0M0SSN3|A0A0M0SSN3_9CYAN AMP-dependent synthetase OS=Hapalosiphon sp. MRB220 GN=AMR41_05690 PE=4 SV=1
EAGEFNNILKQLDINTGNTNTLPDWFYRKIWRLKQAATYT-NYTGLYLVFLDRLGLGKSICRELNRRNPYITVEAGLQFFKLNRDSYCINPNEPEHYEHL
LESLKADDFCIAQILHLWTYDDYAG--SLEALEDAQQQGIYSLLFLIQAIQ---GSVELQVISSYAQFSPGDK-IAYEKSTLIGFLKTVPLELSWLRCRH
IDLEIQP---VEVNAEHIQRELSVAGSDAEIAYRNGRRLSSSLAKVDMLDQQT-QDIPLKQGGIYLVTGGLGGIGTYLCQFLIKEYNAKLITVGRTELPD
RTRLSKRI-KSYLSIEAVG-GEFIYKAVDICNLDGLLDVVTQAESIWNEQLSGIIHLAGEENDHWVTVETQKTFDSMLRPKVHGTWTLYQLIKNNPQAVF
ISFSSVNSVFGGATFSAYSAANSFLDCCSVYQRYHLHQQTYCFNWAQWDNLGMSQGNPERDAALGMGYYIISKEQGLSSLLAALYRNQAHLIIGLDGSNR
NIQRYTDSKSYSIQN--LTAYFTASND--SSKA--SFTELIVRDRFGTKSTCNFVGLQQMPLTDTGEIDREQLKTKSQERSGASKWVAPRTEIERQLASI
WQQLLSVPQIGIHDNFFELGGHSLLATQLISRVQDMFQLELPLRSLFENPTVAQLSSVIVQR----------
>tr|D8G898|D8G898_9CYAN HctE OS=[Oscillatoria] sp. PCC 6506 GN=OSCI_3900012 PE=4 SV=1
IAGDFDSILKHLDIATSNGNTLPDWFYRPIWRPKVAIPAT-TITGATLIFLDSIGLGTYLNVELENRNPCIKVAIGDEFTKIDTNHYKINPKHAEHYLQL
LASLLEDKIAIVRILHLWTYQAYLG--NLEALEESLDLGVYSLLFLTQSLK---AAVQLQVISSYSQPSPDDK-IASEKAPILGLVKTIAQEIVGLKCRH
IDLPIDS---VAVNAPYILTEIQTDSNDSEVAYRNGQRLIPRLEKVYLTIAEK-QKLPFQAGGMYLLTGGLGGIGVEIAKYLLETYQARLLLVGRTQLPP
RSVVAQKI-GAYLALEKLG-GEIIYEAVDICDFTQLQQVVNQAQSLWQCKLQGVIHSAGIYQEGLLVKETKDSFAKTLHPKVFGTWVLHQLILKHPNPLF
ISFSSVSSFFGGAMVGAYSAANHFLDCFAHYQKYQCSIESYCFNWSTWNEVGMSQGYRGKDALHARGYKSMSAKEGLHSFLTGLYNDRANLLIGLDGSKS
FIQQYTEVTEAVKHP--LNL------------------------------ECES--------------P-KS--------QRKKTATTAKTEVEKTIASI
WKQVLNIDDLDIHDSFFDLGGNSLLVAQVTGKLQEFLQRDISMSEMFQYPTISSIAKHLDSP----------
>tr|M1MGY2|M1MGY2_9CLOT Polyketide synthase PksJ OS=Clostridium saccharoperbutylacetonicum N1-4(HMT) GN=pksJ3 PE=4 SV=1
LDGKFNEIINKIE------DENLNYILTKEWVRKEIQYK-QLSNICV-INNDKN-IDELF----------EKN--NVSFKS-------------------
IDNIA-D-AQENDILLDFFFYDENDL--SQNLSYVLDKASTHIKDIMKI-------LTIIFPTKQSINESDMT-FRINNGFINGLLKTVCLENPFLRCRI
VDFDK-------LNISLLVNELNLSIKDEVAVYRDSKRYIPCLKTANKGN-C--NEAIIQYDSLVLVVGGLGGIGIHVSKYLINKYNSKLLIIGSSDLEK
N------I-DRYNKLINIS-EDVIYCKADVTNYQEILDSVNKAEHQFEIKLSTIVNLSGKMSDHTLENEEFKNMLDSSSVKLLGTYNLEKIRKSKEDASM
IVFCSLTGNFGGISMGAYSLANTLQENYCQSLIN-LGERVFCINWSMWSKTGLNKYSNSSS-AVFGGFNELDIDQGIGYLNFIIENNIKSSYVGINRDCL
KMRYQVHDFYDMSLI--INLDDKNK-----QKVKNYS-------NLTSRLVC--------------KIDKS----------RFN-SDANISELQNKLMMI
WKDNLKVEEIHINDNIFDLGGNSLTIFKIVEIISYEFNMNIKPIDIMIYPNIYQLSTYLYSK----------
>tr|E6UAT1|E6UAT1_RUMA7 AMP-dependent synthetase and ligase OS=Ruminococcus albus (strain ATCC 27210 / DSM 20455 / JCM 14654 / NCDO 2250 / 7) GN=Rumal_
LKGMYRKYTDSAAGISTSEDEKNKPLMTRIWQEKPCTHEAE--QDCTLLVGTIR------GSIHSLIENYTKVLP--------FSKYDTLPADT--HVSV
I--------------MDFG--QDSD--------------IHTKITILQDEE---YGVVLNVFTSGGFYKPGDS-VN-ENAVFNGILQSYQMENGNIFVKQ
IDVAEGD---ML-----PGAEEITQTNDHVIVYRSGVRYVPYLVSADVDTSV---TQPITEGGLYLVTGITGGVGRKITSFLARNYNCRFIAVGRKSEEA
A------R-EIFRSEQMDE-SVLAYRNIELSDTDQLSSFVADAEQMDGSTLAGILHFAGSVSLHFLVSETMGSFDEALAPKGYAVSSLCKLLEGRPDCRM
LLLSSVNAFFGGSSLAAYSGANSFLNEMALSCME-KHPQVYCINFANLSNIGMSADIPDKESSKKNGFYLLTLEEAASVMLYVLAHHIRFSFYGINLQNR
NMQQFCCEPMQ---Q--RIIAYLPKEP--GQIS--SILGNTAELRFGRLADYEIQSLHRMPQLEA-WKD-TLRSR--GLFASASRLLQPSTETEQAIYNI
WKEVLQIEDFGIDKSYFTIGGNSLNSFRTLEKMNRHFNTELTIADFFTYNSVQEFAELLDQR----------
>tr|W4LZU6|W4LZU6_9DELT Uncharacterized protein OS=Candidatus Entotheonella sp. TSY1 GN=ETSY1_00090 PE=4 SV=1
EAGAFNDVLKHLDSQLEAVNRLPSWFYRPIWRRQNAVRHT-DHRGTYLIFMDRIGLGDHVGKLLAKRHACVRVETGTDFAQLSPHHYCMDPVNPSHYRRL
LDDLATKQVRPDHILHLWTYSKSTG--SLELLEQAQELGLYSLLCLIQAIN---QAVRLQVISSDVQYSSGEK-VACEKAPLLGLLKTISQEISWLTCHH
IDLSVDR---NEINSAHLLQELCVLQKDQEVAYRDGYRWVPRLQNVDFHHEAP-HDIPFKPGGMYLLSGGLGGIGVELARHLLQHYQARLLLVGRTPMPD
MLSVVQHL-QAYQELKRLG-GEVMYRAVDLADKLRLQQAVSQAKSRWGCELDGVIHLAGIFQPRLIMEETRTSLAASLRAKMLGTWSLYQLIKDQPHGVF
IAFSSVNGFFGGATASAYAAASCFLESFMACQQRHRYPQSYCFSWSMWDEVGMSRDYQMKSLSRAKGYHAITAEQGLSSFLLGLRYHQTHLLVGLDGGNP
HIRRHCETLSPGMQT--LRAYCTVKND--VSIS--NLQDVEVLDRFQVPCPCDVLQLQEMPLTPDLNIDRHALSVLAASPGGEADYVPPRTSTEETLVAI
WCEVLKLDRIGIHDNFFALGGHSLIATQVISRIRRAFRVELSLPNLFESPTVASLAERIDAL----------
>tr|Q3MCQ4|Q3MCQ4_ANAVT AMP-dependent synthetase and ligase OS=Anabaena variabilis (strain ATCC 29413 / PCC 7937) GN=Ava_1609 PE=4 SV=1
NTGEFKSVIKHVDILLGNANTIPDWFYRQVWQPKNPITFNSSLTNCTLVFLDAFGLGTYLCQILSERNQYITVSPGEDFRKINHSHYTITPGQAKDYKLL
LKSLATDNITIGQILHLWNYDQYLG--SIEALEAAQEKGIYSLLFLVQAVQ---GVIQLLFISSYVQSSSDDP-IAYEKSPVLGLLKTIPQELPCLNCRH
IDLPFAE---VEKTGTYLLQEMQVSSKEREVAYRNGQRFIPRLEKVDFTSKPK-SPISFKHRGTYLITGGLGGIGIEIARYLLKHYQARLLLVGRTPLIH
H-VITQHQ-KAYQELSQLG-GEVIYEAVDICDLNHLQIIVEKAQSQWCKNLDGVLHLAGTSHEQMILEETQENLAAILRPKVFGAWTLHQLVKDNKGSIF
INFSSVNGFFGSTAVGAYAAANSFLDGFSHYQNSHSELTSYCLSWSMWHEIGMSQGYQLKNLIRTKGFYVMSSSQAISSMLATLQHQQTHLLIGLDGSNQ
NIQLWQS-QAFNLQK--LSAYFTTHSD--DIF---KLQHLTVEDRFGNSCNCNLVKLKEIPLTESGAIDKNKLIRQ-FTGQDTGTHVAPRNKLEQQIADI
WEQVLGRPVFSVHHNFFELGGNSLVGTQVISRLRNTFSIDLSLQSLFKLPTVAELASNIEVI----------
>tr|A0A0M4SRC4|A0A0M4SRC4_9NOSO AMP-dependent synthetase OS=Nostoc piscinale CENA21 GN=ACX27_12195 PE=4 SV=1
NSGEFKSIIKPIDILLGNSNTIPNWFYRQVWQPKSSIAFNSNVTNSTLVFLDSCGLGQYLCQILSENNPYITVSPREDFRKINRSHYTITPGQAKDYQLL
LESLAADNIIIGQILHLWTYEQYIG--SSDALEQAQEHGIYSLLFLTQAVQ---GAVQLLFISSNTQSSVDDS-IAYEKSAVLGLLKTIPQELPWLNCRH
IDLPVAK---VETNGAFILQEIQVSSKEREVAYRNGQRFIPRLEQVDFTSQPK-SSISFKQGGTYLITGGLGGIGIEIARYLLQHHQAKLLLVGRTPLTL
E----KSI-KIYQELEPLG-GEVIYEAVDICDLQHLQIIVAEVQSKWGKNLDGILHLAGAFHEQLVVDETQESLISILYPKVLGSWTLHQLIKDNHGSIF
INFSSAHGFFGSTAVGAYAAANSFLDCFSHYQNTHSELASYCFSWSMWDDTGMSQGYQMKNLIRAKGFYIMSSSQAISSMLTGLQHQQTNLLIGLDGSNQ
NIQRWQS-QFFNLQK--LTAYFTAS----NEV---KLLDLQVQDRFGTSCTCNLVQLNEMPCLENGEIDRTSLMRK-INSQEIKERIEPRNEIEYKIAQC
WQQVLKVPLLGIYDNFFELGGNSLLAGQVIARLREDFSLELSLQRLFQTPTIAGLAQAIEAI----------
>tr|U5QGL8|U5QGL8_9CYAN AMP-dependent synthetase and ligase OS=Gloeobacter kilaueensis JS1 GN=GKIL_1830 PE=4 SV=1
EAGEFLSLQKRMDVLQNNQRTIGDWFYSKQWRQRVLE--VSDPKGAVLVFVDDSGLGSILKPHL----ECVQVEAGEGFQKLGKGHYRLNPTSVEQYGQL
LGSVESEGLHLRHILHLWGCRPYRQ--A-SDLLRAQETGLQSVLALVQAMH---DGLALRVVTNHLQALPGDP-IDCAGSTVLGLLRSLDQELPWLDCRH
IDLPVEE---GEHCRDALLAELVSGRGEREVAYRQGRRWVARLQKVDMVAQVK-QPVPFQKGGFYLLTGGLSGIGRSVAKQLLSQYQARLLFVQPTIEKE
------QR-EALAALMDSG-AEVIAREIDLTNLCGLQEAVEGAKQRWGRHLDGVLHLEQPYRESLVVEETPEQLARFLYPQLQTSWTLHQLLAGQPVGFF
LRIAHASGELGGIVAAGFAAAQSFASAFVQYQRQAGLQNSYCFSFGFWEDFEPGRDYPWRPLAAARGYRFLSRREGWHSLLAALAQGTPSLVAGIDGRSP
AVRPYCLDDLHPLEQ--LTAYYSGE-----IL---PSTLQAIPDRFGRASSCNCMRVKAIPRQLNGQVEEQALIAQSHSRRESVTQAAPQEQVARTIAAV
WQQVLQVDRVGLDDSFFDLGGHSILLVQVQQQLQQVLGRQIALLDLFTYPTVGTLAQFLKQG----------
>tr|A0A073CRH4|A0A073CRH4_PLAAG Mvd OS=Planktothrix agardhii NIVA-CYA 126/8 GN=aerA PE=4 SV=1
EAGEFNPVLKQIDILLENANTIPDWFYRKVWKSKSPVNLK-SSNNYTLIFLDQLGLGEFLAAQIKVKNPFVTVLAGEEFSKLSGDRYTIKPGEAEHYQHL
MESLAEQKITIGNIIHLWTYQEYQG--RIEQLEQAQEQGIYSLLFLVQAIH---DLIQLLFVSSHSQCTSIDE-IAYEKSPVLGLIKTLAQEIPWLNSRH
LDLPIDK---NEINGAYLLQELYVLSKEREIAYREGNRFISGLEKVNLPEQLK-QELPFKSGGIYIITGGLGGIGIQVAQYLLKNYQARLLLIGKTALPE
KHEFSLKI-KNIQALEHLG-GEVIYQAVDVANFTQVQQAVDEVKQHWKGELDGVIHLAGIYKNCLLLDETKQGLAAILRPKVLGTWILHQLLKESQGGIF
ISFSSLASFFGWAALGSYAAANTFLEHLNNYQKSKHLFPSYCYSWTTWQETGMSKGYQMQYLTRSQGYYDMTVQQGLDSFLASLYHNQGQLMIGLDGSNS
KIKRSTS-LSEGLQK--LTAYYIPKPP--NPIH--LGDHLILKDRFGTPYNCSLIPRQSLPLKDQGEIDKQQLIKE-LQGQENREWIAPRTEAEGKVAQI
WQNVLNLPQIGIHDNFFELGGHSLLASQVISRLRDVFSVELSLHSLLEYPTVASLTQTLEVL----------
>tr|R7I2Q0|R7I2Q0_9CLOT AMP-dependent synthetase and ligase OS=Clostridium sp. CAG:411 GN=BN648_00257 PE=4 SV=1
EMGMFDEILQITE------ETQKQYVLRKTMTEIKNSLQDTKVNNCI-VDTSF--LDKPF----------FTT--TIESKQ-------------------
I-----------AEVYDYIF----------------QN----VRKYLQT-------QKVVFPVL----YQKEQ-FSWYRGILPALFRTLAMENTNFHFKL
LFLEE-------NENDLIERECNSLDGYDVVYYSNGKRYIETYETYNAVCKRE-NAAAFMDNKLVVLVGGFGGIGRLLSKYLLENYRNIRLLILGRKKKE
D------V-KELL-ALYPK-EQVLYGTADVTRYEQLDEVIEQAKQEVGREIGCIFNLTARGITHAIEKKREDLYTESAVVKLLGLKNIECVR-MKNNCKM
YVLGSVTADFGMVNMSAYAVSNLLAEEYCSHLPQ---EQVVFIGSSGWNNIGMNLKKNSEDTSKSGFLEGFTAETGIRMLDNILTSGVGSCFAGINHEFK
GLQYCITDPFEENLQ--LVVTSEEQ-----ELVKKYS-------LCQKKITV--------------RIDPL----------RQVRQRDNTEGIEQEIKHI
WEEYLAKDIKSFDDNLFDIGGNSLTVFQITEAVNQIFALQLNPIDIMTHSTIRSFSLLIREL----------
>tr|I4HMI7|I4HMI7_MICAE Non-ribosomal peptide synthetase/polyketide synthase hybrid enzyme OS=Microcystis aeruginosa PCC 9809 GN=MICAH_2230003 PE=4 SV=
GNGEFNSILKEIDILLENDQTIPDWFYQKVWKPRSPVNLK-PSKYCTLIFLDCLGLGASLAEKIQGQNPCITVLAAEEFSQISQNCYTLRPGTANHYQQL
MASLSERKIILSNIIHLGTYQDYQG--TIEQLEKALEKGTYDLLFLVQAIH---DLIELLFVSSYSQFIENDE-IGYEKSPVLGLIKTLAQELPWLNTRH
VDLPLDQ---TEINVSYLLQELSVLSKEREIAYRNGKRLIAGLEKVNLLQHSQ-QELPFKSGGIYLITGGLGGIGRQIAQYLLKNYQARLLLIGKTPLPE
KHQLSLKI-KNLQALENLG-GEVIYQGVDVANFPQVKQAVEQVKKQWQGELNGVIHLAGIYKDCLLLDENQEGLSTILRPKVIGTWVLHQLLKESQG-IF
ISFSSLASFFGGAALGSYAAANSFLESLNSYQKSKNLFPSYCYSWTTWQETGISQGYQMQYITRSQGYYDMTVRQGLDSFLTSLYHNQRQLMIGLDGSNS
KINRFTS-RSEGCQK--LTAYYTRKTV--QSVN--LPNHVSLKDRFGTSYQCPLVLRQSLPIKDNGDIDKRQLLKE-LQGKENNELIAPRTEAERQVANI
WQKVLNLSQIGIHDNFFELGGHSLLASQVISRLRDVFSVELSLHSLLEYPTVASLTQTIEVL----------
>tr|F4XJ07|F4XJ07_9CYAN Acyl-CoA synthetase/AMP-acid ligase II OS=Moorea producens 3L GN=LYNGBM3L_04630 PE=4 SV=1
-AGEFDPILKQVDCLLGNENTLPDWFYRKVWHRKEAVTLRTPTNGRTLIFLDSLGLGEVLCSKLGK-DQCVAVEPGAPDAQLTGNRYSIDPTNPDHYQQL
LKSLVETDQPIPQILHLWTYDEYRGEESSEALEQAQNQGTYSLLFLIQALDGLKSQLNLTVVSSYTQPTSPQDDIAYEKSPILGLIKTCPRELPWLNCRH
IDIPVDD---HHINGFHILREMAVCQKEREVAYRNRNRLVPLLEKADLPQLEKQ-ELPFKQKGMYLISGGLGGIGVEIAKFLLNHYQAPLLLVGRTPLPE
PSTKFAPAYQNLEQLAEQLGGEIRYEAVDICDLAQLQQVVERAQSDWQANLQGVIHLAGIAPEHFLVEETRNSFAATLRPKLLGSWVLHQLIKDKPDSVF
ISLSSVLAFFGGATIGAYAAANNFLECFCYYQRHKTLVRSYCYGSSTWVETTLNRSKQIRESRRALGQYGIFNQQGINSILAGLHHDQHSLILGLDGSNP
YVRRYTQQPPYHRQRVSVYFTAVTELSVAQLQRL------EAFVPFGTSITPKFKQLQAMPLTPAGEIDREQLIS----PSKDTENVLPVTDIERQLASI
WQKVLGVSQIGIDDNFFGLGGNSLLAVQLSGEIEKTFGKQLPLAALFQAPTIKQLAHLLCQS----------
>tr|U9VTY0|U9VTY0_9CYAN Uncharacterized protein OS=Leptolyngbya sp. Heron Island J GN=N836_08730 PE=4 SV=1
-TGHFDQRVKQTDILLANENTIPDWFYEKVWVAKSAHGEAQSVTGLTLILADSSGLGQALQEKLASSDACLLVEAGAEFSQLTAEGYTLNPHNPQHYEQL
WAALSKRDQPITQIVHCWQYGELLSG-SLEELVTTQDLGLYSVLWLVQTLASQPDHATLQIVASNAQATHDQESVAYEKSPLLGLVKTISKEIPWLDCRH
LDLAIAP---IQENVTYIVDELQVLQQEREVAVRDGLRRVPRLQPVGFNDEPAQ-DIPIQPGGFYIISGGLGGVAVEIAQYLMRHYQAHLLLLGRSPLPE
RSEWTAERLL---LLEAIDCDRIQYSAIDICEFDQLLKVVEQLKSQWQVPLNGIFHLAGTAPERLLLQESQASLADTLRPKMQGTWSLHQLAMGQESCLF
VSLSSVISLFGGATVGGYAVANSFLESFSQYQRCEAGLQSYCFGSSTWSQIGVNKGYQGTDARRAQGQMAMSVHQGLDSLLIGLTHRKYQLIFGLDGTKR
PVQCLKNVPVALTHRFQAYGTLAIGHPTNHLAPT------IVDERFDTPSHCEFTVLPELPLTVTGELDREQLSTI--VAAKNPGQTAPRNPVEQELVQI
WQTVLDVDSIGIDDNFFELGGTSVLAARLFLQIEQSFGRVLPLATLFQSPTIEQLAQVLAQS----------
>tr|K9X829|K9X829_9NOST Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II OS=Cylindrospermum stagnale PCC 7417 GN=Cylst_6440 PE=4 SV=1
-AGDFQEVLQEIDIYLNQDKGIPDWFYQKIWRRKEILHSPEISAGFYLLFLDSSGLGESLGAKLNQ--PWIGVEMGTSFAKLSANRYCINPQNPADYQQL
LDSLSQEMKHISQILHLWTYKEYVEESSLEMLEKAQVSGVWSLLFLVQALAKTHNKVNLMVVSTQSQGIDAKDLIAYENTPLLGLLKTIPHEIPWLSCRH
VDLQIDP---VNINRELVLRELKAVTKEPEITYRQETRWIPRLKKIDVTQNFPE-KIPFRQGGMYVITGGLGGIGKKLATYLLKNFQARLLLLGRTSLPP
QNEWIAERFQTLK----QLGGEICYETLDVCDLHNLDQVVQKAQSLWQCSLDGVIHLAGIFQERLLIEETQETFAQVMYPKVLGTWSLYQLIKNKPDALF
ITSSSVNGFFGGAMVGAYAAANRFQEHFSHNQISRNIKQSYCFNWSQWDEVGISRGYSMKILSRNRGYLSISDQQGLESFLIGLCYSSFPLWIGLSGKNP
YIRGYLESKPENVEQLVAYVVNKISLPEKHLSEL------VLSDCFGTLSISSVVELKEMPLTATGVIDYQSLVARIGFSSKSGKLIQPNNEMENQIAQI
WKNILGFSEISIHDSIFAIGGSSLKMIQIHHQLEDSLGQKFSITEMFQYPTIHTLAKHLAQF----------
>tr|B3PCU3|B3PCU3_CELJU Putative BarE protein OS=Cellvibrio japonicus (strain Ueda107) GN=CJA_3004 PE=4 SV=1
-AGAYSKAIQDMDLLLGNEHTLVNWFFTDKWVLAPVAKSAVATRNDLVFFTDRHNAQTLL-QAAGTSVFCI--VPGAECERLSEKLWAVRPGQDEDFYQV
LLQITAESSG-YDVINLWPLYSDTHS---------------------QVLPGTLNSLKYLLVEQ-----FDSQLFSADVEMASGLLRTARYELPGLTTRC
LKIEADH---FNRLLNLILQEVNSTGHEDSVAFLGQQRLKKSLECLHVTQEKL--LPALRRDGTYLITGGLGGIGFEVAQSLVRTVGCQLILIGRSAADA
APVR-----SKMAQLQGMANARVDYHAVDVTDPLQVQALFASI-----PALDGVIHMAALYEANTIEQESMESIAKQARVKLHAAQHLALCQEKNSTGLF
ISFSSIFGYFGAATLGAYTAVNSALEAFSRHLHSHSQLRSLCIAWSNWDDIGMSRGYKNS---DAKGFLALTARQGFQSLLIALEVNEPVVYIGLDETKN
YVAREIVGDCVATSQVAIYYESSMGEPHVDLC-----------DYRGNKIPVIYKPTNGLPRRNDGSVDVDALNL----STPMARSVRAANFTEKQLRGI
WAEILDADHFSLEDNFFEVGGSSILVPTLVKVISETFAKPYTAVEFFKYPCIAEAARYLDAL----------
>tr|A0A0R3IUS4|A0A0R3IUS4_9MYCO Peptide synthetase (Fragment) OS=Mycobacterium sp. H110 GN=AOT93_27775 PE=4 SV=1
-DGEFADIVRRVQTSSASANSLPNWFFRPVWHRRDRLRPA-PIDGAVLILGESGDLGAQLADRLTAQVRVVRATVADVTTAIRTVVYLAAPRAPGDIADS
-------------------------------SPEPLPVGVFDVVRIVRTVFDEERGDGLYVVGSGIEQVTDTDEADPGLAPIPVLLRSAVAEMPGLRVRF
VDLDRTD---QTAGADHVAGELGYSTKDIEVAYRDGARWVKGLER--LPDEPTV-GVAIPSGGLHLISGGLGGLAYELARLLIERFGVRVLLVGHRDPDE
RQS-----YQRLRDI--AGDEAVRFEVADVRDADQVWDAVTSAEDRWGIQLSGIWHLAGAYREQPLATTTESDLTDISTAKVAGARVLHHIALRRPGIRF
VSFSSVNGFFGGSTVGGYSAANAYLDAFTLYQRRS-GISAHSIAWTMWDRVGMSAQVEHLEGTRASGYRVVGRVEALNSLLVALAHDVPHVLVGLDDTKS
AIRARLSGVAPTGQVLVA-----------DLK-------------------QTAPEFPDMPVRDR----YDRIVPTRQSAGVARQWVAARGDTERRVSAI
WRQVLGSDSFGVTDSFFDIGGNSVLLALAQRLVQEEFGRPIALVDLFRYPTVSSLAAYLSSS----------
>tr|A9AYS6|A9AYS6_HERA2 AMP-dependent synthetase and ligase OS=Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785) GN=Haur_2414 PE=4 SV=1
-NGEFSSITKPIDLALANQQTLPRWFFSKQWQPVSKRHNSALLKPSYAIFSDDTTLARELIDVLEQHHDWVLISAGETFSQQG-QHYTINLHDPEHYHQI
AATLAATN--IHDYVHLYSCDLPSEIEHVGDLAAAQYRGTYSLLFLTQALAKQKLSASLTVVSQRSHANQSDQV-IYAAAPIHGLLKTMPLEIDWLSCQH
VDLDAASA---TTNSQQIYYELAQPKPSAEVAYRAGQRLVPQLVEAAQSSPV---ESPLVKGGLYLVTGGLGGIGSQFARWLLQNYNARLLITGSTELPL
GSDWALGTDSSLSKRLIDISNDVHYQAVDITDSAQLARLINDAEQRWNQPLAGVFHFAGAGNLAWITNESLATFEMMFAPKVYGTWALQRALSQRPELPI
VAMSSINSFFGGATFSAYSAANSFLDSFMLHQRQTSHPKALCLNWTQWDNIGMSLNNQIRSLSAERGYNVIGLQQGLQSLLAGISQNQYPLMIGLNADSP
ALRQHLAVSQPLQQNLYTTHQHGPDRYR------------QLANSYFGSATLEWYRVAELPRTSSGAIDLAAL-GQLDATNQQTALDQPTNIIEEQLVSI
WQEILGKPKIGIHDNFFALGGHSLLATQLVSRLRDGFNLEVRLYQLFAAPTIAELANCIAEL----------
>tr|I3TWS9|I3TWS9_TISMK DidF OS=Tistrella mobilis (strain KA081020-065) GN=didF PE=4 SV=1
-AGRFGGLVAAPAAGDQGVVDLP--LARPVWRPAALR-RPDPATRAVIHQ-----------------------------SDGGDA---VAA---------
-------------------------------IAALRDR--------LAPLLTEGSGLRL--GVRGLEADPGDPTPEPATAALAAWAASLAQETARLELRV
VDLDPGAD---AAREAELAEEAGHADPEPVVARRGSRRLARRLEPLDLPAPR---VLPITAGGIWLLAGGTGGLGVELAELLGRRFGARLLLVSRSDATA
DPMKAL----------SAAGVEHLAMTADVTDRAALDAAIHAARSHWGAPLAGIVQMATDGALDGGLADSDAALAATIGPKLEGTRNLVAIARDHGDLPL
IGFGTVNALFGAPTLGAYSAANAAMAAVLAGERTAATGPVTTIDWSMWDGLGLAQGAPARARTRALGYRIIGRSQGLRALLAALALDRPRVVAGVDAGSP
VMRRPRAAPPRPL-----LVPVTRGSVI------------NATDRFGRRVTIGTG-----------------A-AAPAGPG---VADPPRGPVETRIAAL
WCELLERPAIGRHENFFEIGGHSLLLARLRARMVPLAGREIGIVELFRHPTIRDLARLVAAD----------
>tr|U5QGL0|U5QGL0_9CYAN Amino acid adenylation domain-containing protein OS=Gloeobacter kilaueensis JS1 GN=GKIL_1820 PE=4 SV=1
-AGEFLPLQKRMDVLQNNQRTVGDWFYSKQWRQRVLEVSDKEPKGAVLVFVDDSGLGQSLR----PELECVQVEAGEGFQKLGKGHYRLNPTSVEQYGQL
LGSVESEGLHLRHILHLWTYQERQVLESAQAVEAAQQKGLYSVLALVQALAARHDGTALRVVSSGAQALPGEEP-AWEQGGLTGLLKTVGQELPWLDCRH
IDLPLEEG---ERCRDGLLAELVSGRGEREVAYRQGRRWVARLQKVVARVKQ---PVPLRKGGFYLLTGGLGGIGLEVAKHLLTRYQARLLLVGRAEAKA
D-------------RLENLGGAVLYRQADVCDLQAMEAAVEGAGSHWQGALDGIFHLAGAYNE-LLVEQSVVSLQEVLRPKLTGSWVLHQLLRKRPEALF
VGFASVVGYFGAATLGAYAAANSAQEAFAAYQRANGYGQSYCTSWSIWDDIGMSQNNRQ--TLQARGFQAIPAHQGVHSLLAALSSGESHLLIGLDDSRA
AIRLHLENPDRQLLNACLTRPFGGIRTL------------RLPDRFRQPSRCEATQLAALPRTADGRIDREKL-RTLGRAGRVAERIAPRNDLERQLARL
WQEVLNVPEPGIADSFFALGGSSLMLTQLVSRIRDHFRVDLPLQILFGTPTLAGMAKLILAR----------
>tr|A7IE19|A7IE19_XANP2 AMP-dependent synthetase and ligase OS=Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2) GN=Xaut_1011 PE=4 SV=1
-AQLAQ---------GAGARTVPAWFHAESWVRRDLDAEPVPP-RGVVFLGGPDGLAAALAQALEREGPV--VSAGAD-VDGGLQ---VALA--------
-------DARADTVVDLRPLA---PVPAGETLDDFRARAGLELAATLALLQQLGRGPPLTLVTRGG--AGSGEGIDPVRAALRGLLRTAAQEMPGLACRQ
IDVGGLDA---TDLMARLAREIRAPAGEAEVALRPTGRFVPRLEPVGRPREP---ALRLKTGGRYLITGGTGGIGRALASHLAARCRARLLVVGRSAGGS
EED----------------GPDLLTRAVDVTDADALEAAIRVAEEHFGGPLDGAFHLAGISPAG-LAQETAEGLAAAFAPKAVGARVVIEAMARRPGGFV
VLWSSVNAIFGGAEAGAYAAANAALAGM-----VGEGTRVLCLNWSRWQDLGMSAPAGAAEFAAARGFRTLPVEDALASLEAALALGTSPLSIGLDGASP
FVRARVRQPARPLQLAGFVVPRPGPAND------------DLADRFGTPIPCPLRVLDAMPRSADGTIDTEAL-SRHEGVA---AVESGQDGVEAELAAI
WSVLLKRSSIAPDDNFFTSGGHSLVAAGLVHRVRAAFGVDLPLRILFEAPTLRGMARWIAAN----------
>tr|I3TWS5|I3TWS5_TISMK DidB OS=Tistrella mobilis (strain KA081020-065) GN=didB PE=4 SV=1
-AGDFDARLAALGLTRDRGPGLPDWFLEPGD------A-PAPPLAGAPRLGL------------IEDR--------------------------------
-------------------------LPRGMALADAIDRR-------RALLARLAG-QTLVTVTPAG--DV-------TAAAVDAFTAAAAEELPGLHLRR
IVMADGTP----ALIT---DEI-ARGTLPVVHLAAGGRTRPVLHPARLPDTP---AQGIAPGQSWLVTGGHGGLGRALIRHLLDRGVASVTVIGRHMATA
DDP----------------RVHAL--SLDLAAADA------GARLAVLGRFDGIAHLAGLYRER-AAEEDGRAVAELAAPKT-GMLPAL-ARLLRDDGLL
IAFSSVVAHLPAAGTAAYAAANAALEAEAAALRRPGGPHLVTIAWTNWDGPGMGAAVGAAGLARGRGLLPIPPADGLASLDVVLAAGLTRAVIGADRRHP
MIAARCIDPELSPARAVLLV--AGATLR------------RAEDIFGTPAGPGLRHVDHLPESDDALVVLA-----AGGDT---AAVAPRTATETALAAI
WSELLPAPVAGIDADFFAAGGHSLLAARIVTRINDHFGLHLTPAALFDAPTIRALAAHVDGV----------
>tr|F7NDS7|F7NDS7_9FIRM Lichenysin synthetase A OS=Acetonema longum DSM 6540 GN=ALO_00920 PE=4 SV=1
---NYEAL---QRAQQTAAGSWDQWLYEPVWRPQENGREAVNGQGIWLIFAHRSGIGERAKRLAERGERAVVVYPGESFACLEKDIFCSSPSRQDMNRLF
QETLHSGRDCCRGILHTWSAGAGRKEISAADLEQAQELGCLHVLQLVQAVRECSGMFNRPRLWLVTKGSQPVLAVDVAQAPLWGLGRTLALEQQELWGGL
VDLDAA--APDEQAADRLIADLLVHDGEDQVAYRQGRRYIARLQR-HIPSGKRDISFRCAANGSYLITGGLGDLGMQVARWLVQQGAKWLILMARTELPP
RSAGYITNIKELEAM----GASVYLAAVDVGDERQFKAFLTRYREEYWPPVRGVVHAAGTVADALLTACEPAAFRAVLRPKVQGAWHLHHLLQDDPLDFF
ILFSSISTLVSSPRLGSYAAANAFLDALAH-QRRQLGLPALSINWGPWADIGMAARSQKTA-LTAAGTNPIPPAAGLQ------------ILEALAGRDL
-EQVAVMD---M-DWEQWGAIFQQAGKAGLFEDLLQEIAATVSSAASGEGSVRA------------GL-------------LGAGPEERRQLLEQYLCGQ
TAQVLKLPRLDVNAALNGMGLDSIMAVELKNKLERTLGVVVPMVNFLQGPSIAELAAQVQEL----------
>tr|A0A0D3V7R8|A0A0D3V7R8_9BACL Uncharacterized protein OS=Paenibacillus sp. IHBB 10380 GN=UB51_07420 PE=4 SV=1
---DFDEII--KDLHFSNENTIPDWMYRMQWNKKNLLTTKRSVSGTTVIFSDSCGLVEELSHEWDRN-NFIQVQVGQRFEKLNENVFRMNPKLLEDYCLF
SE-LTNKGVIINEIIHLWNYDEVWMVTNVDALREAQFLGSYSLLFLAKALSRYAPDHSI-RFTVVASRLHGVLEVSFEKSTLVGILKTMEHELTDFSFKL
VDV-----YPSENAAQTVRNEFFNYDDNHIVAFRNGERYVPVLKK-INPLHSSRKPLPFVKGGLYLITGGLGGIGKQVAAHLLDNYNAKLLIIGRTPLPE
RRYERIQHLLELESQAK-DGAFVAYHATDLCDANKLKQIINDVEQSENTRFSGVIHLAGILHEERLADASVEKLEEMYEAKVYGTFVLTQLLKGQKEALF
VSSSSVTTLSAPMMLGAYCSANTFLETFSSFQRQTLNMDSRCFSWSLWDGIGMSRETAFTG-ATTSGYLHITNKLGMFSLLSGLKTGHSQIYVGLDGTHP
NQKLSVTK---SRNQTVFHAFFKVE--TGVNEHSVLSINKTQLKAVL--SSNNG------------NV-------------LYA---EPRTSTEQVLVGI
WSKLLKVGRIGVLDNFFVLGGHSLKAIQLFSIVRQSFGVDISFKELFSQPTIEGLAYHIDQA----------
>tr|Q6E7J8|Q6E7J8_9CYAN JamL OS=Lyngbya majuscula PE=4 SV=1
---LFDLVAQANTLLMTLEADLSNWFYEINWQTQPLPSTNGNQTGNWLVFALTSELTECGKELAQKGHNCIWVSPGSEYQQLDAQHYQINPTVAEQSQLL
QD-----NADIKGIVHLWGVDETKE--SVGELAKAQELGCATALHLVQGLTQAGLTQVV-PMWLVTQGTQTVLVVQPQQGSLWGLGRVMRLEHPELTCCR
VDLDPK--SPVADTLPILVDELLFNNQEDQIAIRQGVRYVARLVQ-QQPSTEVAEQKSIQAEASYLITGGLGALGLEVAQWMVKEGARNIVLTGRSAPKE
AA----KTIRELE--T--AGASVNVLLGDVSTQEDVTKIFQQMVEASLPPLKGVIHAAGVLDDGVLQKMSWERFTKVMAPKVSGTWYLHQLTQDLPLDFF
VCFSSMASMLGNYGQGNYAAANGFMDAIAHY-RRGQGLPGLSINWGAWATAGMAARLAREH-QNMQSSVAIDPESGMQALGSLLSGSQSQ----------
---VGVFP-------VNWPEFFRQMP--GMAKLPFFSVEQSQKDR------ILE------------QL-------------NVASDREQEKLLTSYLQSR
VAHFMGMTQIELEKSLTVMGLDSLMAVELRNQIQTELAVDIPATRFMEGITIIALATEIKQQ----------
>tr|Q20CI8|Q20CI8_BACCE Cereulide synthetase B, CesB OS=Bacillus cereus GN=cesB PE=4 SV=1
RLGYYEKLSKEIDILLQNDRTIPAWFYEQGFVRKETEITFPKETRKIVIVGESTAFVTTIKRKLEVGHHCYLVGNRE------------------AYLSI
LKQ---E--EIDDVINLLNYEKQD--ADGNEIEKIRNANENGIFFISETIKAGKENLRIFTVTNNCEYSNIMKN-KYHFGTLDGFSRSVNLEL--PNLMC
IRIDLD---VSENDVNSIIKEIAAIHRDDKVVYREGKRYVDSLQPIDMPLSL-QNEIALIKDGIYVVTGGLGGIGKEVCKLLLQQFSAKLFIVGRTALST
SPT----HLASLEELQGFS-KDVHYIDGDLSDAAFVASISAKVEEIWGTELDGILHLAGAGSEIDCTTESKAYYEEMFAAKVFGTVNLFQLIEGKKDALF
LHFSSVNSYFGGASFTAYAAANNFQDTFCQYVSNQGYKNAICINWSMWYDIGMSRNNTNNELMAEKGFLLLPMKQAVYSLLAVLRTGVNNIFVGLDASKS
NIRKSMKQ-KKELGLKAIV--YHTDE---------VDLS-IEAKK-----HVSFLKVDEIPIDEKGCVQIGKLQDLHKNVGKTEMFQEPQSEAEKTLAKI
WRDVLKANKIGRDSNFFELGGHSINATQLVSKIYSVCRVRMPLKNVFQYTTLATMARVLEELLD--------
>tr|N0D736|N0D736_9ACTN Uncharacterized protein OS=Streptomyces fulvissimus DSM 40593 GN=SFUL_6815 PE=4 SV=1
QDGTLDERLHAVATRGTGASFIPPWFFVETEQPR-----IPAADGQPVTLGGGPAERAEVTRVL---SEALSVRADG-----------------------
--ETERPDGTVDAVVDLRLTRA---GWDGRAVYELISDTT-----KAIGAHAGPAKLRIALVTAAGQAHDDL--ARAHLGALQGYVRSVNAEAGEPVVVW
CDLDAV----DEANVNLLARELVTYAAAPAVAYRSGVRTERALSPAPRDPAGV--PAEIKEGGQYIVTGGLGGVGRELCRFLAEKYGARLVVVGSTPAEQ
LDE----SRSALRALE-AR-TRTRYVSVDLASADAPELLRAALRSAAEGRVDGAFHLAGLGGEALGARVDDGRLARYTALKVHGMAALAGA--LTKDALL
VGFSSVNAYFGGAGYAEYSASNSALNASVRSLRDQGYRRALSLGWSAWSGTGMSGGAGASMPIERRGFLSLDVDLALESVDIAVRRNQPVTYIGLDGAHP
DVASHVRR-KPGWEPVPRY-FYVAE--SEL----PSEIT-ELAP------ALRSSRVAQIPRKGDGHVDTVRLLQ---TVSSTTAAAPPETATEQRLAAL
WEEILGTENLARDDDFFMLGGHSLMAARLANDIRRAFGVTVALHEFFKSSRLSAVASLIDEKS---------
>tr|A0A0F7CQC3|A0A0F7CQC3_9ACTN Vlm2 OS=Streptomyces xiamenensis GN=SXIM_47770 PE=4 SV=1
AAGEYDEELRATALRGARQRVIPPWFFTETTHPR-----VPAPAGRPVDLGGSPADREAVGRTL---AAALTVVSGP-----------------------
--AAEHPTETLDAVVDLTLTRD---GWDASDVLRLITATA-----ERQAAEPGRA-RKILLVSVGDRGRDAA--ARAHLGALQGYVRSVHGDAHDPAVIW
CDLDTL----DEANAAALAAELTAPSGAAVVAHRAGVRSERVLAPAPAVAPGTAAAPVLTAGGTYLVSGGLGGVGREVSRFLADRHQARLILVGSTPLDR
LDA----ERRELNALA-AR-TEVRYLAVDLAAPDAAARLREA---AGPGAVDGAFHLAGLG--TLGQTVDAERLARYTAVKVGGLFALAEV--AGPAAPL
IAFSSVNAYFGGVGHTEYSASNSALNEAVRVLRAQGHRAAVSLGWSAWTGLGMSKG--NTVPIERRGFLSLDPDLALESLLLALGHDRAVTYVGLDGAHT
DVAAQVRH-KPGWRLVPTY-YYAAD--GEI----PAEIA-ALAA------GAESALVPQIPRRRDGQVDTVRLLQ---SAGTRATGDRPATETERRLAAV
WERILGTEDLARDDDFFSLGGHSLMAARLGNDIRAEFGVTLALHEVFEDPTLSAIARVIDEKS---------
>tr|Q1PSF3|Q1PSF3_9ACTN Vlm2 OS=Streptomyces tsusimaensis GN=vlm2 PE=4 SV=1
QDGTLDERLHAVGTRGAGAAFVPPWFFVETDQPR-----VPAADGRPVVLGGEAAERAEVTRVL---SRDLAVQAPG-----------------------
--E--APEGTLDTVVDLRLTRA---GWDGRAVSELIADTT-----KAIGAH-TAATLRIALVTVAGRARDDL--ARAQLGALQGYVQSVNAEAGAPVVVW
VDADTV----DEANVALLARELVAYAPAPAVAYRAGARTERALAPAPRDPGGV--AAEIKEGGRYLVTGGLGGVGRELSRFLAEKYGARLVLVGSTPAGQ
LDE----ERAALKALE-AR-TDVRYVSVDLAAADAPDRLRAALRSVADGRIDGAFHLAGLG--GLGARLDADRLERYTALKVRGMAALAGE--LAKDALL
VGFSSVNAYFGGAGYTEYSASNSALNASVRTLREQGYRRAMSLGWSAWTGTGMSGGAGAGMPIERRGFLSLDVDLALESVDIAVRRNQAITYIGLDGTHP
DVASQVRK-KPDWALVPRY-FYVAD--SEL----PSELT-GLSA------ALVTSKVDRIPRKADGHIDTVRLLQ---AASTTAAAAPPETPTEQRLAAL
WEEILGTENLARDDDFFMLGGHSLMAARLANDIRREFGVPIALHEFFKSSRLSAVAALIDEKS---------
>tr|A0A0K6JUC1|A0A0K6JUC1_BACPU Linear gramicidin synthase subunit B OS=Bacillus pumilus GN=lgrB PE=4 SV=1
KDGAFRDIEQALDLASENEQTLPDWFFKRIWAKEKIGPAQPFA-DHVLVFEDEKGLYQSLYAQFQKNQPYISVRKGHEFLRLSKGMYQINPRIKGDYVRL
IAALEADELKTGRMLHLWNVSDKEDIVDPAHFKELHASTNQSILYLYQALRQNKEPIRFVVVTKGGQFVQPEDDLHVEKTPLVGLLKTIPQEWEGAEVSH
LDIEAE---NVEQDAKHIAEELSAIHIKTEVSYRNGDRFVPKLEKVNMMEAP-QTEGFLEYEGLYLLTGGLGGIGFELSKQML-QFGLKLVLIGRTSLED
SLE----KKEAFSQLKGF--GDVIYVQADVTNLCDIEQAIYEAEKHFGQSIRGVLHLAGAGQQADLAHTTEEDFTKEMSGKADGAWVLQEAFKYDPTVPL
VFFGSVNGFFGGTTFGAYSAANSFLDGLAHALTFQEGRRAISLNFSMWDNLGLSKGHTGAALTVRKGFQLIGKKQGLHSLCLGVRLNEAHLFIGLDGANP
DIAGYLQP-APIPVFEKKL-FYTVQPGKEV----HVEIT-SVAAG-----KWDIQQVQEIPKKKDGSIDHEALKLNHDKNAQSLEKQLPETKTEQVLAAI
WEDILDVDRVYKEDQFFDLGGHSLKATQTISRINHEFSMKAPLKILFESKHLAHLAQMIDDIKG--------
>tr|A0A0J6R6Z5|A0A0J6R6Z5_9BACI Peptide synthetase OS=Bacillus sp. LK10 GN=VK97_03050 PE=4 SV=1
KDGVFHDIERALDLASENEQTLPDWFFKRIWVKENIGPSQPISTDHVLVFEDEKGLYPSLYAQFQMNLPYVSVKKGHEFLRLSKGMYQMNPRIKGDYVRL
VAALEADELKIDRMLHLWNVSDKEMIASPAQFKELNASTSQSILYLYQALRQNKEPMRLVVVTKGGQFVKPQDELHVEKTSLAGLLKTIPQEWEGAEVSH
LDIEAE---NVEQDAKHIADELGAIHLKAEVSYRHGQRLVPKLEKVNMMTAP-QTEGFLEYEGLYLLTGGLGGIGFELSKQML-QFGLKLVLIGRTSLEE
DRE----KEASFSQLKDL--GDVLYVQADVTNLCDVEQAIYEAEKHFGQSIRGALHLAGAGQHVDLAHTTEEDFVKELSGKADGAWVLQEAFKHDPSVPL
VFFGSVNGFFGGTTFGAYSAANSFLDGLAHALTYHEGRRAISLNFSMWDNLGLSKGHTGAALTVRKGFQLIGKKQGLHSLCLGVRLNEAHLFIGLDGANQ
EIAEHLQP-APIPHFEKKL-YYTVQSGKEV----DAKIT-DIIEG-----KWDIRQVEDIPKKQDGSINHEALKQFHHKHAQPFEKQLPETKTEQVLAAI
WEDILEVDRVYKEDQFFDLGGHSLKATQTISRINHEFSIKAPLKILFESKNLAHLAQMVDDING--------
>tr|W6I0M6|W6I0M6_BACPU Nonribosomal peptide synthase OS=Bacillus pumilus GN=BPJ03490 PE=4 SV=1
KEGVFRDIERALDLASENEQTLPDWFFKRTWAKEHIGPSQPAA-DQILVFEDEKGLYQSLYAQFQRNQPYVSVKKGHEFLRLSKGMYQMNPRIKGDYVRL
VAALEADELKTGCILHLWNVTDKEAIVKPAQFTEMHARSNQSILYLYQAWRQNKEPLRLVVVTKGGQFVNAEEDLHVEKTSLVGLLKTIPQEWEGAEVSH
IDIEAE---QVEQDAKHIADELSVIHIKAEVAYRKGHRFVPKLEKVDMMSVP-QTEGFLEYEGLYLLTGGLGGIGFELSKQML-QFGLKLVLIGRSSLED
NLE----KKEAFSQLKDL--GDIIYVQADVTDLADVERTIYKAEKHFGQSIRGVLHLAGAGQQADLAHTSEEDFTKELSGKADGAFVLQEAFKHDPAVPL
VFFGSVNGFFGGTTFGAYSAANSFLDGLAHTLTFQEGRRAISLNFSMWDNLGLSQGHTGAALTVRKGFQLIGKKQGLHSFCLGARLNEAHLFIGLDGANP
EIAAYLQP-AQIPTLEKKL-FYTAMPGKEV----HVEIA-NITKD-----GWDIQQVQEIPKKQDGSIDHEALKLNHHKHGQSFEKQLPETETEQVLATI
WEDILDVDRVYKEDQFFDLGGHSLKATQTISRINHEFSIKAPLKILFESKHLAHLAQLIDDIKE--------
>tr|A0A0P7GG95|A0A0P7GG95_9BACI Non-ribosomal peptide synthetase OS=Bacillus sp. NH7I_1 GN=AKG37_14135 PE=4 SV=1
KDGVFRDIERTLDLASENEQTLPDWFYKRIWAKELISPTQPST-DHVLVFEDEKGLYQSLYAQLQKNQPYISVRKGHEFLRLSKGMYQMNPRIKGDYVRL
VAALEADELKPGCMLHLWNVSDKEDTLDPAQFKERHAGTCQSILYLYQALRQNKEPIRLVVVTKGGQFVQPQDDLHVEKTSLVGLLKTIPQEWEGAEVSH
LDIEAE---NVEQDAKHITEELSAIHLKAEVSYRKGHRFVPKLEKVDMLEAP-QTEGFLEYEGLYLLTGGLGGIGFELSKRML-QFGLKLVLIGRTTLEG
SVE----KEEAFSQLKGL--GDVIYVQADVTNLADVEQAMYEAEKHFGQSIRGVLHLAGTGQHADLAHTSEEDFTTEMSGKAAGAWVLQEAFKYDPTVPL
VFFGSVNGFFGGTTFGAYSAANSFLDGLAHALTFQEGRRAISLNFSMWDNLGLSKGHTGAALTVRKGFQLIGKQQGLHSLCLGARLNEAHLFIGLDGANP
EIAEYLQP-ASIPVFEKKL-FYTVQTDKEV----RVEIT-SVTEG-----NWDIQQVQEIPKKLDGSIDHEALKRNHHKSVKSLEKHLPETKTEQMIAAI
WEDILDVDRVYKEDQFFDLGGHSLKATQTISRINHECSIKAPLKILFESRHLAHLAQMVDDIKG--------
>tr|B7I0Z6|B7I0Z6_BACC7 Linear gramicidin synthetase subunit D OS=Bacillus cereus (strain AH187) GN=BCAH187_C0024 PE=4 SV=1
-NGAYREITQKIDCHLQNEKTLSQWFYREKLVESKLGKSVSSQKE-------TYVFFRQGKSFHHLTQSVVIVDVGETFGEIHPNHYQINPKNKMDYVRL
FEELAKRNVEVFHLLHAWNYCDTVPFRSVEDLANAQYLGVFSVMFALQAIMH--AKLPLRRVTVIATNSVGLKEMNYSCSTLEGYVKTLPAEFENLQVKY
IDIEGKDIQF---DTETVWKELQQQETIPVVLYRDEKRYKIGLEKVPML-EQKEKNIPFQQQGFYIITGGLGGLGTLVAKLLLERYSANVLLLGRTEIET
NAE-KMRLLDSLKE-YEQYGGTVQYKMCNVMDLDAMRKVVHSQEERLQQKVNGIIHLAGIIQEILIEKQTEKELHAMFEAKVYASWVLHEIVKERQDCLY
ITTSSARTLLPGMTISAYCSANRFVENFAYYQR-SQNVNSYCFSWSFWNEIGMGTNLLIKNALIAKGFQLIDDQKGIYSLLAGLKGNEPNVFVGINHEKE
EMAHLIGT--EEQETQQL-TIYITPEYLHILEEVFSIL---NREEFGGLE-KEIVILPKLPLDEYGKVDQTRLAHASDSRFGKKQHIVPRNDIEEKIAFI
WEGLLNKKDISVLDHFFELGGDSLKATQMISALKKNFAVTITQQEFFQSSTVEELASLVEK-----------
>tr|A0A081L7S5|A0A081L7S5_9BACI Peptide synthetase OS=Bacillus sp. DW5-4 GN=BA70_09625 PE=4 SV=1
-DGAFRDIERALDLASENEQTLPDWFFKRIWAKEHTGPSLPASTDHVLVFEDEKGLYQSLYAQFETNQPYVSVKKGYEFLRLSKGMYQMNPRIKGDYVRL
VAALEADELKTGRMLHLWNVSDKEKIVDPAQFKELHESTSQSILYLYQALRQNQEPIRLAVVTKGGQFVKPQDDLHVEKTALVGLLKTIPQEWEGAEVAH
IDIE---AENVDQDAKRIAEELSAIHMKAEVAYRQGHRLVPKLEKVDMIEAPQT-EGFLEYEGLYLLTGGLGGIGFELSKQM-LQFGLKLVLIGRTPLEE
--------DGEKEKAFTKGLGDVIYVQADVTHLSDVEQAIYEAEKHFGQSIRGALHLAGAGNVSTLAHTSEEDFIKELSGKADGAWVLQEAFKHNPTVPL
VFFGSVNGFFGGTTFGAYSAANSFLDGLAHALTFQEGRRAISLNFSMWDNLGLSKGHTGAALTVRKGFQLIGKKQGLHSLCLGVRLNEAHLFIGLDGANP
EIAHLQPASMPRFKKKLYYTVQP------GKEVNLDDITG----VTVGDWDIRE--VPDIPKKQDGSIDHEALKLNHYQNVHQIEKQLPETKTEQVLAAI
WEDILEVDRVYKEDQFFDLGGHSLKATQTISRINHEFSIKAPLKILFESKHLAHLAQMVEDI----------
>tr|R8CX55|R8CX55_BACCE Amino acid adenylation domain-containing protein OS=Bacillus cereus HuA3-9 GN=IGA_03667 PE=4 SV=1
-KGQYIDIQKRMDLTLGNENTLPNWFFRKTWIKRQLSVGIQKTIDAALIFGSHEGVAGNLASHIRGGGKAVIVEVGKEFLQLSEDHFIVNPNRQNDFEAV
LSKIK---VTPTYFVHAWQCDVESNM----------ELGLYSLISLFNAIDKGISPLNLTLITKYAWGVLETELANPMAAAMTGILKTAEQERIGLQCLH
FDFD---SLAPALVAKAAYQELMHGDMEKELAFRKGNRMIPKLINAELLKDVST--SPIKREKLYLVTGGTKGIGSLTVKMLIEEFAAKVLIVSRSKVEK
--------DTEFAKYIEKHKKKILFVQADVANLVAIADAVKKAEDYWQEPILGAFHFAGVMEERLIEEESPESIATVIKGKVMGAESLIEIFSSRPDSFL
MLSSSVNGYFGGFKAGAYSAANAYLDALPSAVG-ENGPKIYSISWTQWEEIGMNKDSLLVELSKAKGFMSISASQGMASLLATLCQSSGNMIVGLNPNKH
YVAHMILPVRPGDLLQCYYSGEV------QPNRILGNLSKYDEFGTVFDFNIIW--LEEMPVDAMGAPDKSLLKKAINKEFTSSKFREPQSNTEKKLADI
WKEILNANKIGVADNFFELGGNSLLATQLVSRIRSHFKIELLIESLFKNATLGALGEEIDSK----------
>tr|K9WBM1|K9WBM1_9CYAN Polyketide synthase family protein OS=Microcoleus sp. PCC 7113 GN=Mic7113_1753 PE=4 SV=1
--------------------------------------------SCWLVFVDECGIGSQIARIENEGQDVISVRVGEQFDQVSEWEYTINPQRKEDYHSL
LKKLDFLDKIPSTVIHSWSITSHEQIPGVELFEEAQHLGFYSLLFLTQALSKQTIPLRLWVLSNSMYAVESTDVSYPEKITLLGLCKVIPQEYSNITCQS
VDLVLPKLGSKDKLIDQLLAEITGKSSDLVIAYRANQRWRQVFEPVRFDNPVES-PKQLRQGGVYLITGGLGGFGLTLAKYLVQTVQAKLVLTGRSALPP
KEEWVSTRIRKIQE-LEDLGADVLVISADVANEIHMRRVITQTEKR-FGKLNGVIHAAAILDDKSILDTSYTESNWHFQAKVYGLYTLDKVLQDREDFCI
LMSSMGAIF-GGTGFASYTAANLFMDAWVHRQNQLGNSNWCSVNWFHYEDAFLALRGIAPDP----RKIEVFHEQVVEIFKRLLSNRIPQVIWQSDIETE
-----V-------------------------DKLIKH----KSSQ-------Y--PEKVKSEATPSLYPRS----NL-----RTTYVVPSSEIEHRIAQL
FQEFLGIDKVGIHDNFFELGGNSLIATKMFLIIRQELQVEIPLISLFQKPSVAELALFIEEI----------
>tr|C6WBZ9|C6WBZ9_ACTMD KR domain protein OS=Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971) GN=Amir_3682 PE=4 SV=1
--------------------------------------------ETCLLLSEGPL-GREVARLEDLGVHAVFAPVDP-----------DGRADQHRYREL
LADLTARDRTPRLIVHLRPFEAA-GADDLDAVREGQITGLHSLLHLAQAIGAGSEPVRLVAVTRGAQAVLG-DLAHPEHATVASAVKVIPRELPRVSATA
IDVDAGSA----GLADRIVAELL---SPTEVAYRGPQRFERD--YHPL-PLG----RAPEPGGVYLICGGLGGIGLSVAEHLAP--TARLVLTRRTPFPG
SGAD--VLADRLAA-LTAGGAEVLVRQADVADETRMREVLAEAESR-FGPVTGVVHAAGAPDA---QRRSRHDTDDAMASKVLGPVVLDTILGDRPAFFV
LCSSIGSVLHLKFGEVGYVAGNDFLDAFAAHRASRRPGLTVSIAWTDWRDEGMWGTV-H--PKLDDLLGAISRSEGTELFARILAGNP-RVVCALDLGAL
LA--RH-------------------------EAFST---------ED----HRA---A-VLRIARSRRDRS----AL-----SSAYREPGTATERGVADC
WATLLGDDPIGADDNFFELGGDSLVALRLLAVVRERYGVELSMAQ-FEGPTISDLAAAVERG----------
>tr|A4KUB0|A4KUB0_STRHI TlmVIII OS=Streptoalloteichus hindustanus GN=tlmVIII PE=4 SV=1
--------------------------------------------GRCLLFSSG-PLGHAVERLVAAGVDV---------ERVADPAICFDPDRPEHYREL
VA---GRGGAPRLVVHLWALEDALARGPSGLMPEVQRRGLHSLLHLARALGAAGGPTRLVAVTGGAQEVLGDDLRHPEHATALAAVKIIPREYPGMACTA
VDLDLTRLDDLDWLAERVVDELLAARESTVVAYRGRRRFRLDHAPCPLEPGDPA--VGPRPGGVYLVCGGLGGIGLNLAEDLGR-LPAKVVLTHRRPFPA
AEDWTSVAINRLRG-IIEAGGEVLVAPADLTDSDAVRAVVAEAERR-FGPLTGAVHAAGVPDAGVIHRRTTADTEAAIAAKVHGTAVLDEVLGDRPDFFV
LCSSIGSVLHLKFGEVGYVAGNDYLNAYAAYRAARRPGITTAIAWTDWLESGMSAVAQERLVDRAGDLLGATRDEGVEVFRRVLRAGGPQVVSTQDLDAL
-----L-------------------------ARHDAY----TTGDHL----A------VVGLSAHGGRSRA----RL-----STAYAAPRSDLERTLAGW
YAELLGYDQIGRDDDFFELGGDSLLALRLRSMVRSGYGVEVSVAQLFDAPTVTGLATLVGHA----------
>tr|M3C9I4|M3C9I4_STRMB Beta-ketoacyl synthase OS=Streptomyces mobaraensis NBRC 13819 = DSM 40847 GN=H340_10245 PE=4 SV=1
--------------------------------------------GGCLLLGDGDT-AKAVARLEALGVPVTTV--GG-----------GRPPGPERYREL
VGP------ATRLAVDLWPLRDASHRGGAAGVRTAQDAALHNLLHLARAFGALRHPARVVTVTTGAHDVLGDDLAHPEHATVPAAAKVIPREYPWIACTA
LDVEPGLD----RLADLIVRELG---ETTVTACRGRRRFTPCPVRQPL-PAA----PAVRPGGVYLVCGGLGGIGLHLAEYLGR--ARTVVLTHRRPFPA
PGAWPEAVVRRLRS-LAATGATVVVRRADLTDHDAMRALADEVEQA-HGPVRGVVHAAGVPDA---QRRDRAGTDAALAAKLTGTLVLDEVFAHRDDFLV
LCSSIGTVLHLKFGEVGYVAGNEFLDAYAAHRAARRPGRTLSIAWTDWRE-GMWAAA-Q--RRLGDLLGAISPEEGVDVFARLLAADP-NVVSAQDLDEL
LA--RH-------------------------AAYTT---------DD----HLA---A-LLRIAAA-RDRS----AP-----AAPYAAPHTPAQRRIAGW
YRDLLGVEHVGLDDDFFALGGDSLLALRLLSQLRDAYGVEISVAR-FDEPTVAALAAATGPP----------
>tr|A0A081BVS0|A0A081BVS0_9BACT JamP protein OS=bacterium UASB270 GN=U27_03387 PE=4 SV=1
--------------------------------------------QQWLVFLNECGLNSKIVQLQQHHQEVFIVKAGSSFSKMTDHEYTLNMRQPEDYNLL
FNDLQSMNVRLNKIVHLWNVTGNEREQILERLDISQNRGLHSFLSLAKAIGNHSDEIALLVVSNNMQEVTGDELLYPEKATLLGAVKIIPQEYQAVRCRS
IDIVLPESGQEAKLVEQLLRDFTTPSEDIIVAYRGNYRWKQTFEPLRLEHARKE-HTRLRDRGVYLITGGLGGIGLVLAEHLAQKARVKLVLTGRSAFPA
KEEQISQKIRKIQA-IEATGSEVAVFSADAANLEQMAEVVAQTEKQ-FGQIHGIIHCAGIP-YKVIQRRSREDTEEILAPKVKGTLILEHLSQHTRDFFI
VCSTIGAILHMKFGQVGYSAANEFLDAFTYYKTSRDGTFNVSINWNDWKEVGMSERAEQRWVASAVRHGIMLPSEGAEVFDRILEQSAPRIVSTQDLPTL
-----I-------------------------VKDAEA----A---AT----F-L-ETPQTSKAAKSTDARP----EL-----STTYTEPGNTIEQELVEL
WQQFLGIEPIGIYDDFFELGGDSLLGTQIMARSRETFNVDIPMGRLFEDPTIAGIAAYIAKN----------
>tr|V5UVT2|V5UVT2_SORCE Polyketide synthase OS=Sorangium cellulosum GN=mscG PE=4 SV=1
--------------------------------------------QRWLVFLDRSGWGEALAQLRAGGGEVVVVRPGDVFQGEGGRDFVVDPASAEQHRQL
AGALDQGAGVPRRVVHLLGIGRAADGD-------EQLTAFAGLASLIAALGRRDPAIELTVVSRGAQSVTGDEDLDPGSAALPALVRAAEQEHAWLTCRS
VDVSDRELG--AWLADRLIAEALSSSPAQLVAYRGKHRWEPTFEPLATGPDGQ--AGGLRQGGRYLVVGGLGGAGLGIALHLAGAFAAQLLLVEDPDVPA
PAD------------PR--AASVQVIRARIDDPGELSRAVREAEAR-LGGIDGVVYAAGVDD-AGIGDLRVADVVSRLAHHGRAIPALESALAGRSDFCA
VSSSLSAILG-GRGLGAYAACSLLRDAHVRRQ--RSAQRWVAVNWDRWLDGARREGREVFHAEGAGPSQGLEPEQALRALERILASPLDQVVCSGDLAAR
-----L-------------------------AQGRRA----EPDAAP----A-R-RAE-GAGAPADGDDRP----DL-----STRYVAPRDEPEEAIAEV
WRELLGMTRIGVEDDFFELGGHSLLATRFLVRLEERLGTQLTIADFFQRPTIAALAARARET----------
>tr|V5UWF6|V5UWF6_9DELT Polyketide synthase OS=Jahnella sp. MSr9139 GN=mscG PE=4 SV=1
--------------------------------------------RRWLVFLDRAGWGEALVALRSARDEVVVVRAGAAFEGQAQGGFVVDPSIPEHHRRL
VEALDQGAGVPGRIVHLAGLDRTPGDA-------ERLAAFVSLASLIGALGRR--PLSLTVVSNSAEAVTGEEDLAPGGAALRALARAAGQEHATLTCRS
VDVSERELG--PWLVERLIAEARSISPEPLVAYRGRHRWVASFDPIPIGGNDE--VGRLRQGGRYLVVGGLGGVGLAIARHLAGARAAKLLLLEEPGVQQ
PVE------------PAPGAVAIEVIRARLDDPGELSRCVREAEER-LGGLDGVVYAAAIDD-GAVGDLRTPDVVSRMARHERALPALEAALAGRRDFCL
IGSSLSAILG-GRGLAAYAACHLLRDAFVRQQ--RTAQPWITVNWDRWLDGPRRE-------AA-GEPLGLDPAQALRALERILDDPLDQVVCSGDLAAR
-----L-------------------------DQARRV----EIDAAP----P-A-QRAGEALPPAEAGDRP----DL-----PTPYVPPRDEIEEATAAI
WRELLGITDIGAEDNFFELGGHSLLATRFLVRLEEQLGVQLKIADFFGHPTVAELAALVRDA----------
>tr|A0A0B9C847|A0A0B9C847_PECCC Polyketide synthase type I OS=Pectobacterium carotovorum subsp. carotovorum GN=RC88_06745 PE=4 SV=1
----------------------------------------------ILMFHHDDSFSGQFS-LIQQGASLLHVVAGEKYA--GDDHYRIEPGNEMHMKLL
IQDLAETAMLPDWVVHLWCLGNQDET-----TDRIQSQGLYTMVAWCKAYNELTVNFHTLLVADRMISIVGEEDIEPAKSTLLGISQVLPKEYQDIQCHL
VDIAPNFQA---QTIRMLLAEMG---SSSEIAIRGVHRFVKDYARYSVSETQL---SLLSGNKTILIVGGLGNFGLELAEFVALNYQAQVYLTTRTRFPA
RSEWVSEKILHLQR-IEDLGGRVEILTADITCLQDLVQINTLLQTR-HRRVDGVIHAAGTVD--MIHTKTRDSLEQVFSPKIAGTMNLCDVFLPLNDFIL
LCSSMNAIIG--LGQVDNTAANAFVDAWAEHCHQRGYTQVLAINWGAVNEARARNY-SAQP-QFEHIKNKMSQDEIFEVYRRLFS-TGSRVVSTLDFNKV
-----I-------------------------ENWSRV----GSVASLT-QKV---T---------SRSRDE----FV-----QTSWKDPLSTYEITVAKH
WEALLGIDRVGNDDNFFELGGNSLIVLQLISLLKKDYPIKMHAMA-YEHPTVREFAAHVEQL----------
>tr|E5B8A6|E5B8A6_ERWAM Beta-ketoacyl synthase OS=Erwinia amylovora ATCC BAA-2158 GN=EAIL5_2891 PE=4 SV=1
----------------------------------------------VLMFHHHDQFSSLFS-LIRQGATLLQVSTGEKYA--AEDHYQVVPGDEKQIAQL
INNMSENKILPDWVVHLWLLGNRDAT-----TDSIQSQGLYTMVAMCKAYSQLPVDFHTLLVADRMVSIVGEEEIEPVKSTLLGISQVLPKEYQDIQCHL
VDISPDFQP---QIALRLLAEMG---VSSEIAVRGAHRFVKDYARYTLPAAQL---SLLAGDKTILIIGGLGNFGLELAEFVALNYQARVYLTTRTRFPA
RSAWVSEKIRCLQR-IERLNGKIEILTADITCREDILRINTLLRDR-HERIDGVIHAAGTVD--MIHTKTRDSLEQVFAPKITGTINLCEVFLPFNDFIL
LCSSMNSIIG--LGQIDNTAANAFVDAWAEHCHQRGYPQVLAINWGAVNEARSRNY-SALP-QFEHIKNKMSQEEIFEVYRRLFA-SGSRVVSTLDFNQV
-----I-------------------------ENWSRV----GSVASLM-QKV---T---------PRSRDE----FV-----QTAWSEPTTEYEASVARH
WGVLLGIEQVGNDDNFFELGGNSLIVLQLIGFLKEDYPIRMHAMA-YEHPTVREFAAHVEQL----------
>tr|C5AG73|C5AG73_BURGB TubD protein OS=Burkholderia glumae (strain BGR1) GN=bglu_1g16910 PE=4 SV=1
-----------------------------------------------AD-----------------AARCTYVVPGTGFAA----TFAIDPAREDDYRQL
LDALAAGAGLPRYVVHAWLTPEADWDG-PARFAEHQTPGLFSLIYLARTLNLATGSCSVLVAASQLVALP-GEALHPDKATVLGISRTLQKEYAFIDCRI
VDVAARELF-ASPSAARLGL----LAANEIVALRHGRRWQSVYERFAVPAE-----PQVAAEGLYVVFGGLGELGLSVADYLASRAACTILLLNSSRFVP
REQWPYRKIERIRA-MERRGATVCIERCDITDAQALGATLDAARAR-HGAIHSVIHAAGRVENGMIDNKDIAHFDTVFAAKVYGTYHLLAYLRP--TKLI
LCSSMNSIIG--LGQIDNAAANAFVDAIAQTGL-AAELGVCSTNWGAVNAERLTRPN-----VLHMR-NHMTEQEIAAVYDRILHWNGPRLIS-TDFDSV
-----L-------------------------EHWGEV----SKVTELARAQE-----AGT---------RAG----E-----DDGQV-YRSDLHRFVERS
WAAILGA-RLGWDDVLLEQGAHSLSAVQFVSMIKDRYQI--GLMIIYEIRTLGLLVEHIEAK----------
>tr|A0A096YVV4|A0A096YVV4_BURTA 3-beta hydroxysteroid dehydrogenase/isomerase family protein OS=Burkholderia thailandensis (strain E264 / ATCC 700388 / DSM 132
-----------------------------------------------AA-----------------AARCLYVVPGAGFGE----TYCIDPASEGDYQRL
IETLAARGRLPRRVVHAWLAAEAAWDG-PANFANCQTLGLFSLIFFARSLNRVSAACSIVVAASQMAALP-REEVNPDKATVLGISRTLQKEYPFIDCRI
VDIASHELF-ATDSAAQLGL----LPENEIVVLRGARRWQTTYQRFAVPAK-----PDVQARGVYVIFGGLGELGLNVAAHLASRAPCTLLLVNSKRFVA
RDEWPYKKIEKIRE-MEKAGATVLLQQCDVADAKRVDAVLDDARER-HGVIHSVIHAAGRVENGMIDNKDVRHFETVFEAKVYGTYNLLSYLKP--TKVI
LCSSMNSIIG--LGQIDNAAANAFVDAVAQTSL-AASLGICSTNWGAVNAERLTRPN-----VLHMR-NHMTEREIAAVYDRILHWNGPRLIS-TDFDSV
-----L-------------------------EHWGEV----SKVTELARAAE-----AGE-----QASARAP----D-----DDGYA-YRSELHRFVETS
WARILGV-HVDWDGVLLELGAHSLSAVQFVSMVKDRYDV--SLMIIYEIRTLGLLVEHIETK----------
>tr|A0A0A8FBP2|A0A0A8FBP2_9ENTR Polyketide synthase OS=Dickeya zeae EC1 GN=W909_06750 PE=4 SV=1
--------------------------------------------RGVVIFMDKAGVAERIAQLEQQGARVCRVVAGKPFSRKSPLSWVIDPALPQDLEAF
ASSLRKQAFPLDHVIMCWPVAR-RALS--------ATDYYECLLNIARQFTDYQTPLLLHVISNALHVVTPDEQGDPARALLVGPCRVLEKEFEQLTCRS
IDIDLPPRPARDHNLAPLMAELTS-GDDSFVALRGGVRYIQSLEPIVAEPVDEE--LPVMRHGRYLLTGGFGGIGMTIAQWLAQHYQAHVILLGRSDVPP
EPQWKSLKIKQLQK-IKQLGGTVSVIAVDLGNTRQVSQALKAVSRT-QGMIHGVFHCAGIADR-LIQQRTAADSLAVFNAKVQGTLVLERYFRRRPDFFV
QCSSLAATVG--MGQVAYCSANAYQDAWAIA-RQRTHTRYLSVGWDSWQEVGMAVDS-----LKAVIRHGIRPQEGSELMARLLARQESQYISTRGLPLP
-----D-------------------------ADTTTQ----P---D-------A-QTE--ELETQQLYPRP----PL-----ANAYIEPRDAVETTIARI
WQEKMGIGPIGIEDDFFELNGHSLMAVQIIAQIRQQLAVSFPVGFIYDYPTIAGLAGQVRLR----------
>tr|A0A0A3ZJW2|A0A0A3ZJW2_DICCH 6-deoxyerythronolide-B synthase OS=Dickeya chrysanthemi GN=NM75_05100 PE=4 SV=1
--------------------------------------------RGIVLFMDKTGMAERLAQLEQQGARVCRVTAGKRFSRKNPLNWVIEPNAPQDLAAL
ASSLEKQKFPLDHLILCWPVSR-RALP--------AIGHYETLLSIARQFAGAQTPLLLHVVSNGLHAVTPTDRCDPARSLLVGPCRVLEKEFEQVVCRS
IDIDAPSRVAFDRNLAPLLAELGA-GDEQFVALRGGARYIPSLEQVVAEPADEA--LPVLTHGRYLLTGGFGGIGMTVAQWLAQHYRAHVILLGRGDVPP
QSRWKSLKIRQLQK-IQQLGGTVTVIAADLGNARQVTQALKAVTHA-HGAIHGVFHCAGVADR-LIQQRTPADSLAVFKAKVWGTLVLERYFRRRPDFFV
QCSSLAAAVG--MGQVAYCSANAYQDAWATA-RRRTHTRYLSIGWDSWQEVGMAVDS-----LKAVIRHGIRPQEGCELLARLLVRQAPQYISTRGLPLP
-----D-------------------------ADTPAE----D---D-------A-PAE--G-QETSLYPRP----PL-----SNAYLAPRDHIEQTIARI
WQEKMGLGPIGVDDDFFELNGHSLMAVQIIAQIKQQLKVAFPVGFIYDYPTIAKLAGQARLR----------
>tr|T2I4E7|T2I4E7_SERPL Putative polyketide synthase OS=Serratia plymuthica GN=zmn18 PE=4 SV=1
--------------------------------------------RTVVLFMDRLGSAKRLAMLENQGARVRRVSKGIRFRILRSGSVTVNPQRPQDFHLL
AEYLRSQQQAPDALIHGWSITRSRALS--------ATLHYESLLHIARHFHPEDAPLDLFVLSNHLHALAGDEQSDPGKALIIGPSRIIPKEFSQIRCKS
IDFIPPSRYATTRALSTLLAEMQH-DEAPMVALRGAQRYAPLTE-LDCGPQTEP--FSFCNGGNYLITGAFGGIGSTIAENLARRHRARLLFIARGELPP
EAEWKSRRIAFLRQ-LQQAGAQVTVISADLADKRSVGRGIAAFTQR-YGTLNGIFHCAGVADG-LIQNRSADDSQRVFQAKVQGTRVLEACLRQHADFFV
VCSSLAAFVG--VGQVAYCAANAWQDAWALNQRRDARTRYLAIGWDAWRDVGMAVDS-----LRKTLRDAITPKEGWTLLTQLLARNGGHYISTRGLPLV
-----D-------------------------SDANVQ----T---D-------I-AQPDREGLQPALFPRP----PL-----SSEYLEPRNETERQITAA
WQEKMGIGPLGIEDDFFELNGHSLMAVQIIALIRQRLNVSLPVGFIYDHPTVAALSEQVLMR----------
>tr|K9EKE9|K9EKE9_9CYAN Polyketide synthase family protein OS=Leptolyngbya sp. PCC 7375 GN=Lepto7375DRAFT_0333 PE=4 SV=1
--------------------------------------------AAWLLFVDDTAHSQAIARLSMA-HVAVTVHPGDSFSRLDQHTFTVNPHRPEDYRAL
LNGLG--DHRPTEILHGWSLTSATD------FNEIQAQGCQSLLYLTQALTQCHHDLRLTVLAANILNVTGTEPLSPGHATILGPCTVIPQEYRQITSRL
VDWPVNADSDLNVLLAELAAGSEEPSVEPTVAYRHGLRWVQRFSPMPLPEAEP---ALLRQQGVYFITGGLGNVGLTLAASLA-PWQAKVALLSRRSLPD
REQWICDKIRQIQT-METAGVEVLILAADVADAAQLGGAIAKTEAR-FGPINGVIHAAGAV-EQMIAETGSAELEQQFQAKVTGLQNLAAALEGKSDFGL
LCSSLASVLG-GLGFAAYSAANYFMDTFAQQRS-QASFPWMSINWDGWRFQPDEHPE-----LGTMADFALTPAEGNAVWQRLFAYAVPQMVSTGDLTAR
-----Q-------------------------QQWQPA----PA---------------PADEANRPQYDRP----AL-----AGDYQAATTPLEQEVVEI
WESFLGIRPIGIDDSFFELGGHSLLATQIMVHLRQQFQVDIPLRCLFDQPTVAGLARAIVEY----------
>tr|U9W039|U9W039_9CYAN Polyketide synthase OS=Leptolyngbya sp. Heron Island J GN=N836_21435 PE=4 SV=1
--------------------------------------------QAWLLFVDDTALGQGIVQLTA---TTVTVHTGASFERLDEHTFTVNPHRPEDYRAL
LNALG--EYRPNEILHGWGLTSATE------FDEIQAQGCQSLLYLTQALTQCHHDLRLTVMAANILNVTGTESLSPAHATILGPCTVIPQEYRQITSRM
VDWPVDADSDLKVLLAELTAEPD----EPTVAYRHGMRWVQRFTPMPLPEAEP---ALLRQQGVYFITGGLGNVGLTLAASLA-PWQAKVALLSRRSLPD
RSEWICDKIRQIQT-MEAAGLEVLILAADVADAERLRSAIAQTEAR-FGRLNGVIHAAGAV-EQMIAETGKAELEQQFQAKVTGLQNLAVALEGKSDFGL
LCSSLASVLG-GLGFAAYSAANYFMDAFAQQQSKAASFTWMSINWDGWRFQPDEHPE-----LGTMADFALTPAEGSAVWQRLFAYAVPQMVSTGDLKAR
-----Q-------------------------QQWQSA----PP---------------MADEANRPQYDRP----AL-----AGDYQAATTPLEQEVVEI
WESFLGIRPIGIDDSFFELGGHSLLATQIMVHLRQQFQVDIPLRCLFDNPTVAGLADAIVQH----------
>tr|A1TTJ1|A1TTJ1_ACIAC Beta-ketoacyl synthase OS=Acidovorax citrulli (strain AAC00-1) GN=Aave_3732 PE=4 SV=1
--------------------------------------------TVLLLGGAGLPLAERLARLAERRARVVQVAADEGFRRDADGGFGLRPDARGDHAAL
WRA----LGPVTHAFHFWGLEEARGGA----SMAAWQRGYFSLLALAQGRE--DEPLSLTAVIDRAEEVAGSEPLEPGKATVAALARVLGQEMPRIACRV
VDVLVPNAG-EAQLADALAGEPAR-ADEFCVAWRGAQRWVKTYEPAPAPA------RRLRQGSVVLITGGLGSVGLALARHLGRRHGARLVLLGRTPLPP
RAEWQRRRLAQLQA-MEADGIEWMAVAADVTDAAQWRGALQAVHGR-FGGVNGVVHAVMEPGG-MLATRTRAEVEAAFAAKMQGTLAMVDALR--PDFVL
LCSSVASWVG--LGRSDYAAANAWLDAFATARR-DSPWPVFSVNWDAWRDVGVGAGMDVP------EGMGLDERTGMEVFDRVVNGPQPQTVSVTPLAQR
-----L-------------------------RPLDG-----LV-DAL----E-AQ-----APSGGAAHPRP----VL-----STPYRAPEGELEDNLAAL
WTEALGIHGIGADDNLFELGGDSLLAIRLLARVRKAYAVDIHPAA-FKAPRIADLAQLVELR----------
>tr|H8MFK6|H8MFK6_CORCM Polyketide synthase type I OS=Corallococcus coralloides (strain ATCC 25202 / DSM 2259 / NBRC 100086 / M2) GN=ppsE5 PE=4 SV=1
--------------------------------------------TWWLLLPDDEGLGARLAKLGEAGQDVVRITPAAVTAKHDEHHWSLALGG---EATV
LEALTAQGRAPDHVLHLGTLGLGDAH-GEADFESALGKGFLGLLSLAQALGRQTRPVSLVAVTNRMQA-LGDEAPNPELATVLGPVRVIPQEYGHLSAKA
VDVRLPASGQETALVEALLSEAATPKLETVIAYRGGARWVQHFEHVPADAPRTA-QLPLRDGGVYLLIGGFGTLGFSHAKSLAKRAKAKLVLAGRTALPE
RSQWVSRRIRQVRE-LEALGAEVHTVSVDAGNKVQVKEAVDAALTH-FGALHGVVFAAGDV-QAAIPDTRPEDVRDTFHGRVRGLYALEEAVRGRSDFCV
LSSSLAAVLG-GLGLASYSAATSFMDAFATKQAQTSPVPWMSVGWDAWQYESRAGGAQSP--F---GALAITASEGEDAFEQLFQLGVSHVVSTSNLRAR
-----A-------------------------RKWAQP----AAAQEK----A----EAKQAGSSLGTTPRP----AL-----QNAYVPPRDELEEKIARL
WQTTLGIDQVGVHDNFFELGGNSLVGVKLIARVREQFGVALPAVTLYEGPTVGALAKLLKAA----------
>tr|V6MB70|V6MB70_9BACL Polyketide synthase OS=Brevibacillus panacihumi W25 GN=T458_00170 PE=4 SV=1
--------------------------------------------QTWLVLEGEDPWSRLLVRLMEQNQTVISVRKGHAYQVLDENVFVIRPNREEDYAAC
LQEVAARGLRPDHLLHVWLLEEKEFQDPYSVFETYVESGFDSLLSLARTWETCTNAVRLTLLSDRLHDVMGNEQIIPEKTVALAAGKVIAQEFPQIQVSA
VDLDLRHDSSVDNLADFVIEQCRSKHREGVVAYRGNRRFVPAYENMEIETSTP---LSLPQLETCLITGGLGDLGLLIAEVLVKQGVHKLALLGRTPVPK
RAEWMTEKIRRVQS-LEQMGARVMVLEADVSSLDQMRQATDEIIEQ-WGSLDGIFHAAGAV-ERFIRETTADLSSQHFVAKVQGLYVLDTLVTQLRTCCI
LISSLASLLG-GMKSAHYAAANQFMDSFSVCSNRAGKTMWASWNLDAFLFGAEKEQVN----LISFSENAMRPHEFALILPALLARIMGRVVSTIDLNQR
-----S-------------------------QEWVST----GAFAP----------EQAILAHQAALHPRP----SL-----QNPYVAPRNEIEKKICDI
WQRTLGIDQVGIQDNFFELGGNSLVGIKLIAQINEAFSTTLLPVRLYEGPTVQTFAELLGDN----------
>tr|C6CCJ8|C6CCJ8_DICDC 6-deoxyerythronolide-B synthase OS=Dickeya dadantii (strain Ech703) GN=Dd703_3070 PE=4 SV=1
----------------------------------------------WLIFVQEGEASEWLA-IEQRGQPLIRVYAGDTFS--SAKRYVVAVEEPASYLQL
IEHLSSEG--VSHILHGWLFSSKPVS-----SQHALAQGFYSGLSLLKALAAKGQ-QQVWWITDSVFQVLGHETPVPYSALINGLNRVVTQESGRLICRQ
LDLCSGDDI---LAVPAIINEVN---NETLIAFRAGQRWVFAAEPLPLAPVS----ASQTQAGVYIITGGLGQFGLATASYFIRDPQARVILTSRADVGL
YHGQETTRLAALEA-LWRKGAQVDVVQTDAGDEHQVNALLEQTIAR-YGKVTGLVHAAGLIGQ-SFIESDREHCERIFRAKVQGTQILIDALKDIPQFVM
FVSSLSPLLG--LGLTAYAAANSFMDSCATRLNRSQDKHWVSVNWEGWIRQGGVSAD-----YDTFQQLSLSDTEIRLCFERILA-HLSNVVSTGSLTER
-----L-------------------------QRWSTI----AGMAEIT-GTI---D--------------------E-----SLTLGTRRDDKATVILDM
ARQLLGNPALGPDDDLFKFGADSLTAIQLIARIRDLFKVDLPMQT-FDRPTVTSLVCSISAK----------
>tr|U7QEH2|U7QEH2_9CYAN Short chain dehydrogenase family protein OS=Lyngbya aestuarii BL J GN=M595_4608 PE=4 SV=1
--------------------------------------------KSWLIFIDSLGIGTEIAKLINAGQEVVMVSRGETFDEVGYRTFEINPQEKQDYQAL
IEDLNLREFHPDYIVHLWGIEDDK--PSNSSLKTDRNQEFYSLLFLTQAINPGDNTIQVFVVTNPIYNVMGSEEVNPEKATVLGLCLGIGQEYPQLSCRH
LDVMVPTAKNHKKLSDCLLAEFIDEPTELTVAYRDYYRWKRTFKPIRIDANQDK-NIQLRQGGVYLIVGDFSGIGHVLAKYLTENLQAKLILVSSKEIPA
YS-------------------YYLTFKADITNEDAMQAIVEKIDEQ-FGELHGVIYSTPMS-EHLLQQLKPEKCEYGFQEQVKGLLVLEKVLRDKQDFYL
LQSSLSSII-GGIGLAAYSAANQVIDAFANFKNNQNLANKISTLWYSVNWDAIAYQTEQKT-VTNLAEFTLKPDEVCQVFQRILSLKPTQVVSKGDLDTR
-----I-------------------------NQWVKF----KPVS-------EKIDNPQTLQSSASGHSRP----NL-----SQEYVAPRDEIEQAIAII
LQEVLGIEEVGVNDNFFDLGGHSLLAIQAISRLRETFQVELPLRNLFETPTVAGIATVIAQN----------
>tr|Q1D6B7|Q1D6B7_MYXXD Polyketide synthase type I OS=Myxococcus xanthus (strain DK 1622) GN=MXAN_3619 PE=4 SV=1
--------------------------------------------RCWVVFTDGGPLASRLVRLEEAGQYVVTVHAGAAFSRDDERRFTVAPSAPGDYAAL
LSALEDLTPRPEVFVHLWSLTPQGEREILTRFQAAQALGYYSVVHLGQALAGL--PLRVEVISNHLFDPDGRAEALPEKAPLLGPCQVLSQQHVHITARG
VDVILP--G-VAALAEQLVAELATEARDVRVALRGSRRWVQELSPVRLTETAA--PRPLRERGVYLITGGLGRVGLLLASHLARTKQARLALVGRTPLPP
RRLWASLLIRRVRE-LESHGAEVLVLSADVSKPHWMQEVLAEVDQL-FGALHGVLHCADLPLPPPP-SATNPDAEARFRAKVRGTYVLEDVLRDRADFVM
LFSASAAVLS-PFGDTPSTAANLFVDAFAAHR--SAGTPWMSVAWDPWPRAA----------GAGLEPYAMTENEATEAFQRVVTGGDGPVVATGDVSRR
-----L-------------------------TAWLQR----AVALP-----K-----------VARK--V------R-----TGDEELPANELERVIAAL
WQEVLGVEQVARHDHFFELGGHSLLATQVVGRLRSRLQLDLSLALLFTSPTVAGLAKAIADL----------
>tr|A0A0F7BM31|A0A0F7BM31_MYXFU Polyketide synthase OS=Myxococcus fulvus 124B02 GN=MFUL124B02_19435 PE=4 SV=1
--------------------------------------------RCWVLFVDGLGVGEALARLEEAGQDVVRVRQGGAFMRDAAKRYALDARLRGDYATL
WKDLADQDLSPSVVVHLWSLGSSGEEPSPELFRKVQDTGYYSLLHLGQALAKG--PVRVEVVTDRVQDVAGEGTALPEKATLLGPCKVIPQEQEHVSTRC
LDVVAPAPG-VEKLAERLLAELSQRSRDAVVAWRGSLRYAQTHSPLRLEPAGE--ATPLREKGVYLITGGLGGVGLMLAEHLARTLHARIALLGRTALPA
PSEWVARRILRVRE-LEQAGAQVMVVHADVADAAQLEAAVAKVEAR-FGALNGVLHCAGVTQPSPLTDIGRSESETQFGPKVHGTYALEQVLSRRSDFVL
LFSSNAAVLG-GLGYLTYASSNLFMDAFAQA--GRSGTRWVSASWDPWPEET----------KHSMDQYAMTPAEGAEAVRRLVTLGDGQVVATGDLAQR
-----W-------------------------RLWIQR----ETSQP-----V-----A--GARAAGK--PR----RS-----KTPFVAPGSELEKQLAAL
WQEVLGVDSVGLNDNFFDLGGHSLLATRVAGRLRTQFDLDIPLAKLFEAATVASLAKLVADH----------
>tr|L7UAL4|L7UAL4_MYXSD Polyketide synthase type I OS=Myxococcus stipitatus (strain DSM 14675 / JCM 12634 / Mx s8) GN=MYSTI_03594 PE=4 SV=1
----------------------------------------------WVVFVDGLGVGEALC-LEDSGQDVVRIRQGSAFM--AARRYALDPRVRGDYATL
WKDLADQELSPSVVVHLWSLGASGAG-GPELFRDVQDLGYYSLLHLGQALATGSRPVRLEVVTDRLANVAGESTALPEKATLLGPCKVIPQEQEHVSTRC
IDLVAPEPRGVEQLAERLLSELS---KDAVVAWRGNLRFAQALSPLRLEPSGD---APLREQGVYLITGGLGGVGLMLADHLARTFKARLALLGRTAMPA
PTEWMAQRILRVRE-LEKAGAQVMVVHADVANAEQLEAAVAQVEAR-FGALNGVLHCAGVTHSSPLTDIGRSESETQFGPKVYGTYALEKVLSRRADFVL
LFSSNAAVLG--LGYLTYASSNLFMDAFAQARAGHTGTRWVSASWDPWPEETK---HTNV--RTSMDQYAMTPREGAEAVQRLVT-LDGHVVATGDLAQR
-----W-------------------------RLWIQR----DTSKPAQ-GAR------------TAGK-PR----RS-----KTPFVPPASDLEKQLATL
WQEILGVDSVGLNDNFFDLGGHSLLATRVAGRLRTQFNFDIPLAK-FEAATVAALAKLVADH----------
>tr|F8CAR7|F8CAR7_MYXFH Polyketide synthase type I OS=Myxococcus fulvus (strain ATCC BAA-855 / HW-1) GN=LILAB_26135 PE=4 SV=1
--------------------------------------------RGWVVFTDGGPLASRLVRLEEAGQHVVTVSAGGAFSREGERRFTVSPGAPGDYAAL
LSGLEDSPHRPEVFVHLWSLTPREARADLTRFQAAQALGYSSVAHLGQALAGL--PLRLEVISNHLFDPDGQAEALPEKAPLLGPCQVLTQQQVHITARG
IDVILP--G-APALAEQLVAELVTTARDFRVALRGSRRWVQELSSVRLTESSS--PRPLRERGVYLITGGLGRVGLLLAGHLARTKQARLALVGRTPLPP
RRLWASVLIQKVRE-LEAHGAEVLVLSADVSKPRWMKEVLAEVDQR-FGALHGVLHCADLPLPPPL-SATGPEAEARFRAKVRGTYVLEEVLRGRADFVM
LFSASTAVLS-PFGDTPSTAANLFVEAFAAHQ--GSATPWMSVAWDPWPRAA----------GADLEPYAMTEAEAAEAFQRVVTGGDGPVVATGDVSRR
-----L-------------------------TAWLQR----AVAQP-----K-----------VSRK--A------R-----TGEEAPPANELERVIAGL
WQEVLGVEQVARQDHFFELGGHSLLATQVVGRLRSRLQLDLSLALLFTSPTVAGLAKAIADL----------
>tr|A0A0H4WVT9|A0A0H4WVT9_9DELT Malonyl CoA-acyl carrier protein transacylase OS=Myxococcus sp. (contaminant ex DSM 436) GN=A176_002367 PE=4 SV=1
--------------------------------------------RGWVVFTDGGPLASRLLLLAEAGQDVVTVQAGTSFAREDDHRFTVAPGQPADYVSL
LEALKGRAHRPEVFVHFWSLTKQGDVASSERFRDTQSRGYYSLLFLAQALGKA--PVRVEVISNHVHDPDGAAEALPEKATMLGVCKVLPQEHQHVATRC
IDVVLP--E-ADTLARGLLAELSTRTRDMLVAFRGTRRWVQEFTPVKMGG-DA--PHPLRERGVYLITGGLGGVGLLLAEHLAETQRARLVLLGRSAFPA
RESWISKLIHRVRA-MEAHGAEVLVLAADVSDAARMRTVVEQVESR-FGVLHGVLHCAGVTHDSSLTELGTQASETQFQPKVYGTYALDEALRGRDDFVL
LFSSNAAVLG-GLGYLTYASANVFMDAFASNARGVGGTRWVSASWDGWPEET----------KHSMDQYAMTREEGAEAVRRLATQGDGPVVATGDLTHR
-----L-------------------------AVWIHR----DAPAT-----R-----P--SGSASRQ--A------R-----KGTYVPPANETEQAIAAM
WQEVLGVEQVGRHESFFDLGGHSLLATRIVGRLRSAFNVDLPLAKLFEVSTVSGLAQAVTVA----------
>tr|B8I980|B8I980_CLOCE Beta-ketoacyl synthase OS=Clostridium cellulolyticum (strain ATCC 35319 / DSM 5812 / JCM 6584 / H10) GN=Ccel_0978 PE=4 SV=1
--------------------------------------------ECWLLMDNGQQMSKLLADFASNNIHVISVTAGEDFIRHGNNEFTIKPSRKEDYNTL
FEAIYEEGYSIKRVVHLWGLYEKEKEL--DHYSKFMDLCFYSIINVTKAIGRYASPLTIDIVTSNMERVKQDEEVCAEKAVVLGPCRVIPQEFPNITCNS
IDIDLNGKATA----AEIVRELYANCSGDTIAYREGKRWRQDFEEIEIGENNIQ-QPRLKEKGVYLITGGLGGIGLVLAQYLAEETQAKLILTGRSVFPE
KSEWINKKICLLKT-LEAAGAEVVVARADSADKVQMQELIASIRQR-FGGINGVIHTAGVP-GGIIQMRSADKMEAVLAPKVKGTLVLEEVLKGENDFLV
LCSSTLAILG-GIGQVDYCAANSFLDAFAHNYMLKYGTYAVSINWDAWEEVGMAVNSAAQYAPLKKEEDFI--DITHPLFKRYKKETDRVVESKFDIESC
---------------------------------WLLK----EHR-V-----M-GSTIPGTYLEMASATFNI----LT-----ENSYVELQDVDEKENKQV
YTV------FEREDDSYILRVKSFDGQKTVEHVSEEFGT-LDLKEIIGKC---NTSVYIPDT----------
>tr|A0A0E4HBZ6|A0A0E4HBZ6_9BACL Non-ribosomal peptide synthase/amino acid adenylation enzyme OS=Paenibacillus riograndensis SBR5 GN=PRIO_1737 PE=4 SV=1
----------------------------------------------CLLFANDDLISRELL-LRSSGQRVIPVYRGHEFS--DDGEYTIHPESLADYQQL
FAVLQEKQVEADNLIHLWSLENRVSA-DAAAFHESQKNGFYSVTYIVQCLHQFNKAVRIAVVTDEVFPVTGQETLHPENAPLIGLGIVIPQEMQHIRHLT
VDIQAASAAEARELARMLLEELG---RDRQVSYRGLQRWVPIYQPIKLEPQIV---DLFRTNGVYVLTGGAGMIGWIIAEHLAINYRASIAIIQRS-FPV
RPEWTSRTIQEMIQ-AEKLGANIAIYPADVSDYGQMADAIGAIECE-LGAINGVIHCAANMGE-PVTRLDEALCRTIFQPKVDGLLVLDKLLEDKEDFCL
LMSSTAAVLG--YGFAAYSAASVFMDTYMKIRNKHRQVKWKTVDWEAWRREAKAE------AGYSIGDLAMSPEEGIEALTRVLS-AYHHMHSPGILDKR
-----L-------------------------AEWVQL----QGISEGK-PVQ---P-----RDGQKKRQRP----AA-----MVEYEKPSNHLEKQIAGI
WEEFLGIRDISIHDNFFELGATSLTLIRIKSIVEETLSLQIPIVD-FANPTIAALAKRIGQI----------
>tr|A0A0J6BUC7|A0A0J6BUC7_BREBE Uncharacterized protein OS=Brevibacillus brevis GN=AB432_12605 PE=4 SV=1
----------------------------------------------FLVFANRDSLSNEVI-LSSTGQIPIVIYEGVEFA---ERAYTVNPTSSSDYEKL
FVSLTENNIQIDHVLHLWSAGHKSSA-DVLAFHKTQQTGFYSIMYIVRCIQRYHRVIRMAVVTNEAMAVTGQETLFPEHSPLIGLGHVIPQELQNIRHLT
VDIQTAALEDVKRMAQMVVEEFA---SDRLIAYRHFQRWVPSYQPIKLTEA-----DPFRKNGVYVITGGAGMIGWIIGSYLAKQYQATIAIIQRS-FPL
KQEWRSMRIREMME-AEQLGATIEVYRGQVDDYPQMSHIIAEIEAT-HGIIHGVFHCAANMGQ-PIDQLNADLCQTIFQPKIDGLLVLDQVLEQKSDFCL
LMSSTASVLG--YGFAAYSAANVFMDSYTNKRNKQHSVKWKTIDWEAWRNHEKVE------IGYSIGDLAMTPEEGIEALRRVLS-VYHHLHSPGDLEMR
-----L-------------------------DQWIRF----QGSPEGN-AVT---V-----KSARKKRKNT----SS-----MVDYEKPSNQLEQRIAEI
WEEFLGIQEISTHDNFFDLGATSLTLIRMKSILDEEFNRQIPIVD-FANPTISSLAKRIQQD----------
>tr|C7Q555|C7Q555_CATAD Beta-ketoacyl synthase OS=Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897) GN=Caci_6994 PE=
--------------------------------------------GPWLVLSDDER-TETLIRLGEAGAEVVAVRPGAAFD--DVGDFVI--PRLDDFAEL
FES---MLVAPRTIVHGFSLGGVVFDAPVISFSAAQERGYHSALALARYLVDDATPLDLVLLTSGATTVAGADLRHPEHATLAAIAATLSQENPRLRARE
IDIDAVAAGTAERFRAEAVLAAA---YEGPVAERAGQTWLRRYLRH---PLP----AAFKNGDRVLITGGLGDVGLTLSRHLAT-GYGCLILCTRSTLPP
RSAWRTRHVQNILA-LEASGAEVIAMTADVADPVAMQAVVDAAVAR-FGGIDVAVHGAGVQDR-FAHLTEREQSEAHLDAKIRGFLVLDQVLAGHCERRI
TLSSLSAVLG--LTLGAYAASNAGLDAYARAARAAGSGRWVTVDWDTWNIDERLDGH-G--PT--VTDFTMAPAEGVDVFERALAASVGHVIS-------
TGPARL-------------------------AQWVT---------GG----GAD---GGDDDDVRERYARP----DL-----PTPFEEPRPGTEAALAEI
WSAALGVEPVGALDDFFALGGHSLVAIKVTTRIRKTLNASVPATA-LEAPTVRGLAALIDG-----------
>tr|A0A0E4CVH1|A0A0E4CVH1_9BACL Uncharacterized protein OS=Paenibacillus riograndensis SBR5 GN=PRIO_1751 PE=4 SV=1
----------------------------------------------FLLFIDDSGLGEGIQ-LSAKGNRVCTVKMGAGFG--HRDQYEIDPDNAEHYLQV
FRQVFQTGHPVWKIVHMWSSREYMPD----------SGGFYSLLHMGKSFGMIHQQIQLTVVTSAFQSVMGNEVLTPSNAAATGAVHVIQQELQNVRTAL
IELAGEDTGYDQAALELLLEEFI---PERFLAVRGRRKWVRAFEPMQMDHPA----LKQKRDGVHVILGGLGGIGLTAAQALAEQGAGTLILTGRTSFPP
EAEWINQKIRKIIE-LQEQGAQVYLYQVQVSDEKRMNGLFTSIEHT-HGKIQGVIYSAGTVVDFSISGITREMCEAEFEAKIRGLIILERMIRGKDEYCM
VNSSISTILG--IGLAAYTAANQFMDSFVQMMNQQNRTRWMAVDWDAWNFSASDKAG-----GTERLDQFIHPAEGGAVIKALFQVMTEHIVSTTELEPR
-----L-------------------------ALWVNH----SRNNEPG-SQR---E------------------------------SRKELSIEQLLQER
IREATGLSGMGADENFFDAGITSIDIVGMNDSIQQHINRPILISS-YEYPTIKKLAGYLQGE----------
>tr|A0A0C4WWG1|A0A0C4WWG1_9GAMM Polyketide synthase type I OS=Azotobacter chroococcum NCIMB 8003 GN=Achr_38910 PE=4 SV=1
--------------------------------------------GSVLLLSDAHGLGERLAHL-QAQRPVIRVERGAEFARLGERRYAVRPGERDDFERL
LRAVEAESGPLADICHLWSLDPAGLPA----PDEALERGFHSLLALAQALEATRRSVVLSVVANQLEDVTGVEPLCAEKATLHGPCKVIPQEYPHVACRL
IDVVLPPAG-EERLARQLAAELATPEGTPVLAYRGPHRWLKTFESV----R-----PRLRRQGVYLITGGLGGIGLALARHLAGNWQARLVLLGRSALPP
RDEWLAARLQQLLA-LEALGAEVLVLQADVADPAQLRQAVDAARQR-FGALHGVVHAAGAAGG-VLAGKSRADAEKVFAPKLQGTRHLLEALA--TDFVL
LCSSLTAITG--FGQADYCAANCFLDALAAESR-QADRFVLSVNWDTWRETGMAAGQRLP------EKVGIAPEQGGRLLEALLGGPTAQTVSTLDLERQ
-----F-------------------------AQMRTS----ELAERL----L-SP-----AR--RQQHARP----AL-----QTAYVAPDGELEEDLAAL
WSEFLGISPIGVDDNLFELGGDSLLAIQLLARVRSAYGVELHPAA-FKTPTVAALAMLVETR----------
>tr|A0A0K1JVC9|A0A0K1JVC9_9BURK Polyketide synthase OS=Massilia sp. NR 4-1 GN=ACZ75_05725 PE=4 SV=1
--------------------------------------------GPILLLADETSFADKLASL-LAGREVVRVERGSGFERIAANCYAVRPGDAGDLAQL
LQALES--AAVIDVCHMWALNSGSQP-------DALERGFHSLLALAQALDS-VGAAAITVLSDGLADVTGTEQLHPQQAALYGPCKVIPQEYPNISCRL
LDIVLPAAG-EQTLV----NQVIGVQGGTLVAYRGPHRWLKEYEAL----S-----QRLRRHGVYLITGGAGGVGMALARYLARTWQAKLVLASRNALPS
D-------APGLLE-LEALGAEVLAVQVDVGDAGQMTAAVAAARAR-FGALNGVIHAAGIAGG-LIATKQRASVEKVFAPKLQGTMVLLDAVK--ADFVL
LCSSLTAVTG--FAQADYCAANAVLDALSQRAS-GDGPWLVSVNWDVWRDLGMATGHQLP------EDEGIAAADAGPLLERILSGPLPQVISTIGLERQ
-----M-------------------------ARGASM----ELADRL----L-PP-----PR--RQQHARP----AL-----SEAYAEPSGPLEEGLAAL
WIEFLGIAPVGTNDNLFELGGDSLLAIQLLAKVRGAYGVELHPAG-FKNPTVAALAVMVETR----------
>tr|N6YXT2|N6YXT2_9RHOO Beta-ketoacyl synthase OS=Thauera phenylacetica B4P GN=C667_00485 PE=4 SV=1
--------------------------------------------GSMLVIGDPNGLTDRLCEL-RAGRTVVRVEQGHEFAQMGAHRYAVRPGERADLERL
LRHVEAEVGLPSDVCHLWNVELGDVPS----PEEVLERSFFSLLALAQVLGA-GRKVSLTVVANQLEDVTGTEPLCPEKATLHGPCKVMPQEYPHLACRV
VDVLPSADA-LDRVV----QQIVAMDGESVVAYRGPHRWVRTFEPAHPALR-----QRLRKNGVYLITGGLGGIGLTFARYLARQWQARLVLIGRNISSD
Q-------AKAVAE-LEALGAEVLPLQADVADAVQMRAALDEVRRR-FGVLHGVVHAAGVAGG-MIAQRERAAVEQVFAPKVLGTQVLMSQIA--ADFVV
FCSSLASLAG--LGKVDYAAANAYLDAVAADAR-SPGASVVSVNWDGWREVGMAAGTPLP------DQFGIGPEQGVLIFERVATGFHPQVVSTTDLSAR
-----L-------------------------DVNGD-----AILSIM----A-AP-----PHRPDRSHPRP----RI-----SAEYVAPSGDLECGLARI
WTDVLGIAPLGADDNLFELGGDSLLAIQLLAKVRSTYGVDLHPAV-FRDPTIAALAVLIEMR----------
>tr|J2KPR3|J2KPR3_9BURK Polyketide synthase family protein OS=Variovorax sp. CF313 GN=PMI12_02852 PE=4 SV=1
--------------------------------------------TCTLVFGEAGGLAGQLVHLRESAHPVVWVEQGPGFVEIGPRHYAVRPGERADHEQL
LRKVQGGIGPVSNIHHLWGVDGEFAAP---SSSELLERGFFSLLALAQALDSTERKLLLQVVTNRMEDVSGLEPLCPEKATLFSLAKVIGQEYPHIGCRV
VDVVLPVSG-EAWLVAQLAADAPA-RDEPLVAYRGPHRWVKGYEPLALPA------QRLRTHGVYLITGGLGGVGLSVARHLARSWQARLVLLGRSPLPE
RAAWLRQKLLQLLE-LEALGGEVLVLSADVADAAQMQAAAAQARQR-FGAIHGVIHAAGHASG-MISQRTRAMVEAVFAPKLRGTQILLEAVR--PDFVL
FCSSISSMAG--LGMSDYAAANAYLDALAAQRR-SAGHAVFSVNWDAWRDLGMAAGMVLP------EGVGMDGPEGALALERIVNGPHAQVISTTDLAQR
-----L-------------------------GELDS-----GMLALI----E-NA-----ARATRRNHPRP----AL-----DTPYVAPGGDLETGLAAV
WQDMLGITAVGVNDNLFELGGDSLLAIQILARVRKAYDIELHPAA-FKAPTIADLALLVETR----------
>tr|A0A0P9B6C7|A0A0P9B6C7_VARPD Polyketide synthase OS=Variovorax paradoxus GN=APR48_34060 PE=4 SV=1
--------------------------------------------GCTLVIGNADEFQRAFVHLRQAGHAVVRVDHAQAFAEHAPHHYALRAGERADHEAV
LRKVRSAFGPVARIHHLGGIDADAPVA-DAAAETALERGFFSLFALAQALEAVERRLSLQAVLTQSEDVAGDELLCPEKATVFSLCKVIGQEYPHIDARV
ADVVLPAAG-QARLFAQLAAGAHA-TDETRIALRGPHRWVRGYEPL--PA------QRFRQGGVYLVTGGLGGVGLAVARHLAASWQARLVLLGRSPVPA
RTEWLRAKLRQLLE-LEALGSEVLALSADVADAAQMRAVAAQARER-FGAVHGVIHAAGHADG-MIGQRTRARVDAVFAPKLRGTRCLLEALR--PDFVL
LCSSISSMAG--LGMSDYAAANACLDALAALQR-SAPYPVVSVNWDAWRDLGMAAGRVLP------EGIGMDGPEGARALERIVNGPFAQVISTTDLAQR
-----L-------------------------GQLDN-----GMLALV----E-TA-----VRKKRRSHPRP----AL-----STAYAAPDGDLEQGLAGL
WQEMLGIAGVGVDDNLFELGGDSLLAIQILARARKAYEVELHPAA-FKAPTIRELAVLVETR----------
>tr|E6V980|E6V980_VARPE Beta-ketoacyl synthase OS=Variovorax paradoxus (strain EPS) GN=Varpa_4326 PE=4 SV=1
--------------------------------------------GCTLVFAETSGLTDALIQLQAEAHPVFRVTPGSGYAETGAHQFTVRPGERADHEEL
LRKVQAESGPVAKVYHLWSVDGQPSSS-LPQSEDVLERGYFSLLALIQAIDSTARELSIEVIANQIEDASGLEPLCPEKATLFSLCKVIAQEYPHIACRV
TDIVLPVPG-EAWLARQLAAPAQA-HDETLVAYRGPHRWVKTYAPL--PS------QRLRSKGVYLITGGLGGVGLAVARHLAESWQARLVLLGRTPLPE
RSEWLRTRLAQLIE-LENLGGEVLVVAADVADAASMQAAVAEARAR-FGMVQGVVHAAGHANG-MIATRTRAAIDEVFAPKLQGTRFLLDALR--PDFVL
LCSSISSMAG--LGMSDYAAANAYLDGLAALQR-SATYPVISVNWDAWRDLGMAAGRVLP------DGIGMDGPEGARAVERIVNGPFAQVISTTDLNQR
-----L-------------------------GELDN-----GMLDLL----E-TA-----AKKKRREHPRP----AL-----ATPFVAPEGELENVLAGI
WQDMLGIASVGIDDNLFELGGDSLLAIQILARARKAYEVELHPAA-FKAPTLRDLAILVETR----------
>tr|A0A0M8SG13|A0A0M8SG13_9ACTN Uncharacterized protein OS=Streptomyces sp. WM6372 GN=ADK52_05045 PE=4 SV=1
--------------------------------------------ERWLVFADETGVGRRLARLEALGATVRVVSRGADWHREGEREYVLDPARAEHFGRL
AEALRAEGPLPGRVVHCWSVGDDADRA-PEDVRALLHRSFDSLVHWAQAVEAETQQQRWDVLSSEVHSVLGDEPLCPPKAAVQGLCRVLPQEYPTLSCVQ
FDLRLEGPQ--PGLVEQLLADLSA-PGERTIALRGRHRWAPAYAVGEPPARD----SPVRDGGVYLLTGGLGKIGLLMARALADRAKVRLVLLGRTGLPP
REEWVRSAVRAVQE-IEALGSEVLVTATDVSDRAAMLALKARILEE-FGPIDGVLHCAGTTGA-EISVLGEEEASWHFGPKLYGTQVLHEVLADQRDFAL
ICSSIASLLG--LGFGAYAAANAVLDAFAQKHH-SADLPWTSVNWEAWYFSEDRADS-----ELAVRDLALTPAEGRRVFDALLDAAQAQITSTGDLALR
-----Q-------------------------ELWSDP----SA-----------------AAAPVTRHERP----NL-----RNPFVAPSGETEQRVAEI
WQELLGVESVGAQDNFFELGGSSLLGLQVVHRLRQELSVAVPLTI-YEGPTVRALVDNLRAA----------
>tr|A0A0N0YHG7|A0A0N0YHG7_9ACTN Uncharacterized protein OS=Streptomyces sp. NRRL S-4 GN=ADK82_17930 PE=4 SV=1
--------------------------------------------QRWLVFADETGVGRRLARLEGLGATVRTVVQGAEWHRKSEREYVLDPAQPDHFHRL
AEALRAEGALPGRVVHCWSVGDDADRA-PEDVRALLHRSFDSLVHWVQATEAETQQQRWDVLSTEVYAVLGDEPLCPPKATVQGLCKVLPQEYPSLSCVQ
FDLRVESRQ--PGLVDQLMADLAA-PGERTLALRGRHRWAPAYVTGAPPSRG----SPVRTDGVYLITGGLGKIGLLMARALADRAKVRLVLLGRKGLPP
RSSWVRSAIRAVQE-IEALGSEVLVTATDVSDRAAMLALKERVLRE-FGPVNGLLHCAGTTGA-EVAVLGAEEASWHFAPKLYGTQVLHEVLADQHDFAV
ISSSIASLLG--LGFGAYAAANAALDAFAQRHH-SAALPWTSVNWEAWYFSEDRADS-----DLAVRELALTPAEGRLVVDGILDAAQAQIISTGDLTLR
-----Q-------------------------ELWSDP----VA-----------------VPAPARRHERP----NL-----RNPFVAPDSETEHQVADI
WQELLGVESVGVQDNFFELGGSSLLGLQVVHRLRQELAVAVPLTI-YEGPTVRVLIDNLRTA----------
>tr|A0A0A6P534|A0A0A6P534_9GAMM Uncharacterized protein (Fragment) OS=Candidatus Thiomargarita nelsonii GN=OT06_47975 PE=4 SV=1
--------------------------------------------SSWIIFADQG------ILLQAQGERCVLVFVGQNYEK----HYTINLSNPDDFQRL
LEDSLAHYPPCRGIVHLWSQDNGFEND----LRHAQILG---VLHLVQSLIQASQFPHLWLVTQGGQAIGQ----NIEQSSLWGLGRTIMLEHP--EFQC
VCLEGKTDTNPAL-ITLMLKEL--LYKCFPIAKVVAFRYLAQAKQIGKVVI-SL--SIVHGNSSYLITGGTGSLGLQMAQWL-EQGAQHLILMSRQTTTT
DIV-----KHTIAQ-IEQTGAFVSIATADVSDENELNRVLEQIN--QTAPLRGVIHAAGVLEDGMLIGQNWERFEKVLAAKVYGAWNLHQLTAP--DFFV
MFSSAASLLG--RGQSNYAAANAFLDSLAHQRH-QQGLVATTINWGPWAQGGMALSTT----TIGFK--PINTLEGLELMERIIS--ITQIVM-PDWHK-
-----Y-------------------------TTADN---------VLFTTDK-PA-------KP----LAELS-LKLEK-AG--GY-EEKHILSNFVHET
AQQVLGTQ-LDANKSLMELGLDSLQAVEMRNRLGKGLET--TLSLLFNYPSINKLVGYLEKE----------
>tr|K0K8B3|K0K8B3_SACES Polyketide synthase type I OS=Saccharothrix espanaensis (strain ATCC 51144 / DSM 44229 / JCM 9112 / NBRC 15066 / NRRL 15764) GN
--------------------------------------------AWLLFLDADGR-AQALAVLTAAGQVVTTVLPGAEYR--RRGVYELDPARPEHYRQL
FAELRALVRTPSTVLYCWPLAPSA---------DD-TRDYFGLVRLARAVAAEVHDLRLGVVTSGAFAVTGAEHADPVARMLSGPVLVLPTEYHNLDCVQ
LDLPAHADG---TA-TALTRAVL---TDPVLALRGDRWWRREPARATA-PPA----LPVRRGGVYLIVGGLTGIGAALAERLTT-GHGAVVLLSRSAHE-
----P-----TVRA-LADAGATVAAERADVSDVVALTAALDRVRAR-FGRIDGVVHAAGVAGG---ERRTDLEMAGVLAPKVAGARTLLAALRPGEDFVV
LCSSLAAVVP--YGQCDYSAANAYLDGLAE--SRSDGRLVLSAAWDTWGETGMLRDA-EVPGDLEVLARALTTAQGVRAFEALLAGRH-VLARA-GIGEP
LDLGAD-------------------------GPWS-------------------------TGGGVTTAPRP----DL-----AEPYVAPRGELEAQLAEL
WQELLGVDDVGVNDNFVQLGGHSLMAAQLAARVRAAYEIEIPVRV-FEGATVAGLATMVEEA----------
>tr|A0A0M9YV40|A0A0M9YV40_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. WM4235 GN=ADK55_05620 PE=4 SV=1
--------------------------------------------TWLVLCDAEGA-TQPVILITARGQIVTVVRPGPEYR--RRGVYEIDPGDPSQYAKL
LADLRGLVRPPTAIVHGWGLAPAA---------DDGTQGYFGLVRLARAMTEAVNDVRLGVLTAGAFRVLDGERPDPAAALLSGPVQVLPEEYANLRCAQ
VDLAPGAR----SA-LDVLRAVV---PARLLALRGADLLTRAVEPTRP-VAP----AGSAPGAVWVVTGGFGGIGRTLAGHLAR-TAGAIALLGRHPVT-
----DEPAAEFVGD-LRARGTEVLCLRADVADAHSLAEALDRVRET-FGGIDGVVHAAGVPGG---ELRDDDEARAVFAPKTAGIRNLLAALRPGEGTLL
LCSSLATLVP--YGQADYAAANAYLAAAGEAEDARGERRVITVNWDMWASVGMASDA-EVPADLRMLAGALTPAQGTRAFAALLEGPQ-GVARA-GAEVT
DDGLTA-------------------------EPTA-------------------------ARPSTTLLPRP----EL-----ATAYTAPGTPTEERLAEI
YGEMLGIDRVGIHDDFLDLGGHSLLAAQVVARLRAEFGVDVPARA-FEGGRVADLAVDIEDR----------
>tr|A0A062U4M9|A0A062U4M9_9RHOB Uncharacterized protein OS=Hyphomonas sp. T16B2 GN=HY2_01130 PE=4 SV=1
--------------------------------------------GKWVVLADNAAFGKALAGFETGGAEALLGTPSGTCAGDA----------ADSIRTL
NALINEANGALSGIIIALGLEDGANIP----------RLRYDVLS---ALARHERPVRIVLATRGGLPVLEETVTDPEVALAFGAISVLAAETTHLMPQH
VDFADDGKA-SQTNARRLLAEAG-REKFELQLAWRKHRWLRRFEPIELPRAER--TDILKQKGVYLITGGLGGIGRTLARQLAEKVSARIVMTTRNAVPP
RDAWMASVIKTVRE-IESLGGEIHIEQADVVDREAMQGVVDRTREA-WGEISGIIHAAGVPGGN---LETEQEVTETFAPKVDGLRVLADVLGDTEDFVA
LMSSINAVRG-IAGNAAYSSANAFLDSFAASR-PAAWENILLFNWEAWRDVGMASRVDR---SRLLYRVSITPDAGADIFQRVLAS-VDQLVSNYNLAFV
-----L-------------------------MQERAE----LILRAH---GA-D-TSQ--ANAEGAAFSAA----TG-----D---VRFGREEEQQIAMI
WEELLGGEMQGPHENFFERGGHSLMATRVLSRLNAVTGVKLTLRDIFDSPTIGELADCVVSH----------
>tr|A0A059G3M2|A0A059G3M2_9RHOB Polyketide synthase family protein OS=Hyphomonas oceanitis SCH89 GN=HOC_15577 PE=4 SV=1
--------------------------------------------GNWLIVADNPISGERLVGFEASGASALLALVDKDPASVS------------FESQL
SDFAGQLSGGLRGVIIAVGLETDNNIP----------RKRYDLLG---ALARMVEAIRILVVTRGGIPVFDEPVSDSQAALVFGPISMLAVESENLMPQH
IDFSANGDA-SDLNIRRLLAEAS-QEKFESIVAWRERRWLRRFEPVALPPSQQ--LASLKERGVYLITGGTGGIGRTLALWLARNASTRIVLTSRKPLPP
RDEWTSQIIKGILE-IQAAGGEVSVECADVTDRDAMRGVIDRMLQK-WGQIDGIIHAAGSPGGK---MDDPDEVSLTLSSKVDGLNIMAELLRDTPDFIA
VMSSINGILA-APGNAAYSSANAYLDAFPNSR-PDSWKRVMVFNWDAWRDVGMATRIEV---AERFLEKAITPEAGAEIFARLLGS-INQVVTPYNLPQV
-----A-------------------------GRQRQE----IWKRGL---DT-V-LNG--SLPSDASF-GT----SI-----P---IRFAREEERVIAAI
WEELIGGEMEGAHENFFERGGHSLMATRVLSRLNSVAGVKLTLRDVFDAPTIGELADCVIEK----------
>tr|A0A0Q7LDF8|A0A0Q7LDF8_9BURK Polyketide synthase OS=Variovorax sp. Root473 GN=ASD34_10335 PE=4 SV=1
--------------------------------------------GCTLVLGDANSFTDRLGTLREQGGRVILALRGKKFARTAEGQYAMRPAERVDHEAL
LREVESEAGPVTRLFHLWSLDGDAPAP----HAAAYEAGYFSLLALGQALDIGRAPLALTVVTDRVEDVAGTETLAPEKSTVLGIAKVLGQESPTIACRV
VDVVLPAPE-EADLACRVVEEAAA-QEDFVVAYRGPHRWTKTYDALPAQM------QRLRQGGVYMITGGLGGVGLALARYLSKTWQARLVLLGRTPLPE
RTEWLRRRLQQLIE-LEANGAEMMPIAADVTDPAQLRNALAAVHAR-FGAVNGVVHAVVQPDG-MIAQRTQALVEAAFAPKIAGTLALLDALR--PDFVL
FCSSVASLIG--LGRSDYAAANAYLDALAHARR-SSALPVFSVNWDAWRDVGVAVGMDMP------EGVGLDERTGVSAFERIANGPLPQTVSISPFAPR
-----L-------------------------RPLDG-----LF-ESL----D-DP-----APEARTGHPRP----VL-----QTAFVAPEGDLEEGLAEL
WTEALGIAPVGANDNLFELGGDSLLAIRLLSRVRKAYGVELHPAA-FKAPTIAGLAALVELR----------
>tr|T1XDC7|T1XDC7_VARPD Putative polyketide synthase OS=Variovorax paradoxus B4 GN=VAPA_1c38700 PE=4 SV=1
--------------------------------------------GCTLVLGDANSFTDRLATLRERGEKVVLALRGPRFARTAPGQYALRTAERSDHEAL
LREVEAEAGPVLHLHHLWSLDGDRPAA----HAQVFEAGYFSLLAFAHALDAVRGTLALTVVTDRVEDVAGTEPLAPEKATLLGLAKILGQEYPSIGCRV
VDVVLPAPE-EAELARRVADEAWA-PDEFLVAYRGPHRWRKRYAPLPDVP------QRLREGGVYLITGGMGGVGLAMARYLSRTWRAKLVLLGRTPLPG
RSDWLRRKLQQLID-LEADGAEVLPVAADVNDAAQLRGALAAVHAR-FGAVHGVVHAVVHPDG-MIAQRTPALVEAAFAPKIAGTLALLDALR--PDFVL
FCSSISVLIG--LGRSDYAAANAYLDALATARR-SSPLPLFSVNWDAWRDVGVALDMDLP------EGVGLDERTGVLAFERIANGPLPQTVSVSPLAPR
-----L-------------------------RPLDD-----LF-DSL----D-DP-----AAEVRTGHSRP----VL-----QTPYAAPEGELEEALASF
WSDALGIVPVGVHDNLFELGGDSLLAIRLLARVRKAYGVELHPAA-FKAPTIAELATLVELR----------
>tr|A0A0F7BLQ8|A0A0F7BLQ8_MYXFU Polyketide synthase OS=Myxococcus fulvus 124B02 GN=MFUL124B02_19450 PE=4 SV=1
--------------------------------------------KDWVVFLDSTGVGSALAELEEQGHRVARVTPGARLEELGENHFSLDPADADEPGFL
LLALKSKDFKVENIIHLWSLDSREGEQGNERFEQAQARGFHPLLRLTRALTEA--PVELTVVGRQALDVESSDEIAPERATLPALCKVIPQEHDFLSCRY
VDLGRG--PDTRALRQEVT-STATEAREPVVAWRGTNRLVQTHEPVRLEADTQ--PRPFRHRGVYVITGGLGGVGLMIARYLARQHQARLVLVSRWGLE-
----GGHKRRAVRE-LEAAGAEVMLARADVADDMLLSVAITQGALR-FGEVHGVIHAAGLAG-GLLSGLDAAACEPHFRAKVHGTYALELALAGRVDFVM
LVSSNASVLG-GLGLAAYGAANAFLDAFATSK--QGLTRWVSTNWDGWPSVD----------EESLDAFAMTEDEAVEAFRRVAESSGGQVVSTGDLEAR
-----V-------------------------ARWLKR----EGAQK-----N-----Q--DTSGGATHERP----QL-----GTEYVAPTDDLELALAKV
WQEQLGLSRLGIHDNFFDLGGNSLLWLKIVGRLKRELGREVSLTSVFEAPTVAALAKKLGAL----------
>tr|F8CAR8|F8CAR8_MYXFH Polyketide synthase type I OS=Myxococcus fulvus (strain ATCC BAA-855 / HW-1) GN=LILAB_26140 PE=4 SV=1
--------------------------------------------RGWVVYQEAGGVGAALARLEQQGHRVVRVTPGPGFRQVTERDFTVDGREREDHARL
LRALEARDFKVERVVYLWSLDVS-----GADFDEAQARGFFGVLRLAQALSSV--PVELTVVGREALEVESADAVAPERATLPALCKVIPQELDTVACRY
VDVRAP--S---VLLREI----TSEALEPVVAWRGAHRQVQAYEPLRIEADTP--VWPLKQRGVYLITGGLGGVGLRMADHLARTRQARLVLVGRTGAE-
----DGRRLRAVRA-LEAAGAEVLVARADVADEAQLRAVLAEVDAR-FGALDGVIHAAGLAG-GLLGGMDPATCAPHFRAKVHGTYALERALAGRADFVL
LVSSNATVLG-GLGLGAYAAANAFLDAFAAAG--RGGTRWLSTNWDGWPLDSA---------EGSIDQFAMTPAEAVEAFRRVVEAPEGQVVSTGNLDAR
-----V-------------------------AQWVRR----EGAGA-----K-----K--D-AGGALHSRP----ML-----GTEYVAPTDDVERALVRV
WQEQLGLEQLGIHDNFFDLGGNSLLWLKIVGRMKRELGRDVPLTSVFEAPTVATLAKKLGQG----------
>tr|A0A0H4WRN5|A0A0H4WRN5_9DELT Malonyl CoA-acyl carrier protein transacylase OS=Myxococcus sp. (contaminant ex DSM 436) GN=A176_002371 PE=4 SV=1
--------------------------------------------KGWLLFVDSGGVGQALARLRQQGHVVTTVEAGASFSRLDTHRYVVDPRVREDLGAV
LRALKESPRPVEQVVHLWSLDAA------SSFDEAQELGFYSVLRCFQALTEV--EVDLTVVGREALEVESADTVAPERATLPALCKVIPQEQPSLTCRY
VDARGP--G-VDALLREV----TSGSTDPVVAWRGRHRHVQQHESLRLEADSL--TTPLKQGGAYLITGGLGGVGLMLADALARRCQAKLVLVGRAGLK-
----GGR-QRAVQA-LEAAGAQVLVLSADVADEARMREVVAEAEQR-FGPLSGVIHAAGLAG-RLLSGLDAASCAAHFRAKAHGTLVLERVLAGRTDFVM
LLSSNAAVLG-GLGLAAYGAANAFLDAFAASR--D-GARWLSTNWDGWPVAE----------EGSIDQFAMSADEAVEAFRRVVEAPSGQVVSTGGLDAR
-----L-------------------------AQWLRR----GRVVE-----T-----P--AAAGGALHARP----AL-----GTDYVPPANDAERTLAQV
WQEMLGLEQLGVHDNFFDLGGNSLLWLKIVGRLKRELGRDVPLTSVFEAPTVALLAKKLAQP----------
>tr|L7UA36|L7UA36_MYXSD Polyketide synthase type I OS=Myxococcus stipitatus (strain DSM 14675 / JCM 12634 / Mx s8) GN=MYSTI_03597 PE=4 SV=1
--------------------------------------------RTWVVFQDSTGPGEALVELVRAGQRVVRVTPGTHLQELGEHHFSLDPTAPEETFFL
LNALKAKGLDVERVVHLWSLDGSS----TTDFDSAQERGFHSVLRLTRALVEA--RVELTVVGRMALEVESTDEVQPALATVPALCKVIPQEHDGVACRY
VDLGRG--TTVSALARELL----SDSAEPVVALRGAQRLVQTHEPLRLEQDAM--AQPLRTRGVYLITGGLGGVGLLLAGELARSHQARLVLVGRSGLE-
----GGHKQRAVRE-LEAAGAEVLVVRADVADESRLRGVLAEAEAR-FGAVHGVIHAAGLAG-GLLAGLDAAACAPHFRAKVHGTYALERALDGRSDFVL
LVSSNAAVLG-GLGLGAYGAANAFLDAFAASQ--AGTTRWLSTNWDGWPVAE----------EGSLDAFAMSSTEAVEAFRRVVESAGGQVVSTGDLPAR
-----V-------------------------ARWVRK----EGASA-----E---------APTGTVHERP----QL-----GTEYVAPTDDVELALAKV
WQEQLGLAQLGIHDNFFDLGGNSLLWLKIVGRLKRELGRDIPLTSVFEAPTVATLAKKLGGP----------
>tr|Q1D6A5|Q1D6A5_MYXXD Polyketide synthase type I OS=Myxococcus xanthus (strain DK 1622) GN=MXAN_3631 PE=4 SV=1
--------------------------------------------QNWLVFTDTGGLGDALARLAESGGRVTRVSQGSDFRRVDDGVFEVDPTRPETYAAL
LNALAEDSCRPERIVHLWSVDSAGE--GLAGLEHAQRTGFFSLLFLSQALAGQ--PVQMTVVSSGVQAVTGHEVLAPEKATLLGACRVLPHEVPGLSCRS
IDVEAP--RTLQALVARMVGELATGSSNGAVALRGPSRWEQSFEQVRISAPAAD-ASRLRPRGTYLITGGLGGIGLVLAESLARQVQARLVLVGRNALPE
RDTWVSQRIRQVLA-LEALGSEVLVLPADVGDAEQMAEVLRQARQA-FGELHGVIHAAGVPA-GLR---TQKAVEDVLRPKVSGTWILHALLRDTPDFFV
LCSSRTAYTA-EPGQIDHCAACAFQDAFAHQA--TGNVPIISLAWDTWREVGQAVTTQM---PDAMLAHALTPAEGVDVFERVLAQ-PTHVVSTEDLRAA
-----M-------------------------ARSASL----LQDL----------------MGPMETDAAP----AA-----ERAAPASMDEAERELADI
WQRFLGVESVALHENFFELGGNSLIGLKVINEVKRRFGKDLPVVSLFENPTLSAMARLLTRG----------
>tr|Q08QQ6|Q08QQ6_STIAD Oxidoreductase, short chain dehydrogenase/reductase family OS=Stigmatella aurantiaca (strain DW4/3-1) GN=STIAU_6404 PE=4 SV=1
--------------------------------------------QRWLLVTDGQDLDSLLARLRRDGHSVTVAIAGSQAQRTAEDTYEVVPGSRASYAEL
LTLLEKAGRSPERIAFLRPLASCGP--GPEGERKALEVAFHEPLALGQALAEL--PRHLVIVSSGVQAVGGHEPLHPEKAALLGICRVLPQELPHLTCKS
VDVTPP--TLLALLVEQLAQELTGPSSNATLAWRGVHRWEQSYESLSLPPPA---TAPLRPQGTYLITGGLGGLGLVLAEHLARAVQARLVLVGRTPVPE
RQQWLGSKLRKLLE-FEALGARVLALSADTADATHMEEVLHRARAE-FGELHGVIHAAGVPA-GLR---TREATEEILRPKVHGARVLDRLLNGTPDFFL
LCSSLTAVAG-DFGQVDHCAANAFLDAFAQKA--EGARHIMSLGWDTWREVGQAVTTAL---PAQMLAHALSPQEGVDVFGRALAH-QPHLVSTRPLPSV
-----L-------------------------ARSPSL----LQEL----------------AGAGAPSPST----SP-----PPATLSSVDEVESLLGDI
WRRLLGISHVHAHDNFFELGGNSLIGLKLVAEIKQRMGLEFPIVQLFKKPTLGGMARLLSPP----------
>tr|F8CAS9|F8CAS9_MYXFH Polyketide synthase type I OS=Myxococcus fulvus (strain ATCC BAA-855 / HW-1) GN=LILAB_26195 PE=4 SV=1
--------------------------------------------RHWLLFTDASGVGGALARLEEGGGRVTRVSPGSDFRRVDDGGFEVDPARPETYAAL
LAALAAESQRPERIVHLWSVDDAGD--GVAGVAHAQRTGFFSLLFLAQALAGQ--PVHLTVVSTGVQAVTGHEVLAPEKATLLGACRVLPHEVPGLSCRS
IDVEAP--GAQRLLAARLADELSAGSSNGAVALRGPHRWEQSLEPVRLPAPAPD-ASRLRPRGTYLITGGLGGIGLVLAESLARQVQARLVLVSRSGLPE
RGDWTSQRLRQVLA-LEALGSEVLVLSADVGDAEQLEEVLRKAREA-FGELHGVIHAAGVPA-GLR---TQAAVEDVLRPKVLGTWLLHALLRDTPDFFM
LCSSRTAYTA-EPGQIDHCAACAFQDAFAHKV--TGGAPVISLGWDTWREVGQAVTTQM---PDAMLAHALSPAEGVDVFERVLAQ-PAHVVSTEDLRAA
-----M-------------------------ARSASF----LQDL----------------MGPMETDAAP----TA-----ARAVPTNMDEAERELADI
WQRFLGVERVSLHENFFELGGNSLIGLKVINEVKRRFGKELPVVALFENPTLSAMARLLTRG----------
>tr|W4LZ94|W4LZ94_9DELT Polyketide synthase OS=Candidatus Entotheonella sp. TSY1 GN=ETSY1_00115 PE=4 SV=1
--------------------------------------------QHWLVFVDACGLGTQLVRLQQRGQTVITVTAGDEFGQHDAFTYTLNPSEKGDYQAL
FRALQTGETQPNTIAYLWGVTPAAEV-------VEGTPDFYSVLFLAQALGERTDPIRMAVIANQSQAVTGEEPLVPEKSTLIGPCRVIPQEYPHITCRH
IDIVLQKAQGTEWLVDQLLTELVTDAPDPVIAYRGQHRWAQTFEPVELGQ-RD---SALRPQGVYLITGGLSDTGLVLAHYLAQTAQAKLVLTDTMPFPD
RVEWTRHKVEQLQA-MEALGAEVIVLQADETELTQMQEAVEHARQR-FGPLNGVIHIAASR-GGLMQLKSPEQAHQILAPRVIGTQILTTVLHDTPDFLA
LFGSQVSVTG-GFGLIDECAANAFLDAYAHSHGPQCPFPVVAIDWASWHWDQHFEQLAAGVPQLLRETYGITPDEAGEAFERILSSGQPQIVSTQDLQTA
-----I-------------------------EQQNAV----TSTNV-----S--------GQLDTVQPAAP----L------DRDFAAPINETEQRVAAV
WQDTFGIEPIGRDDNFFDLGGHSLLAIQLISRLRDALHLDLPLSSLFESPTVAELAAITTAR----------
>tr|W4LZT5|W4LZT5_9DELT Polyketide synthase OS=Candidatus Entotheonella sp. TSY1 GN=ETSY1_01950 PE=4 SV=1
--------------------------------------------SCWLVLADAEGLGEQLVRLQQQDQTVITVSAGETFHQHDALTYTMNPLQKADYQAL
FQALRTSQQQPDTIVHLWNVTQTAAD-------VEELPAFYSLIFLAQSIGEQTEPIHLAVIANQMHTVTGEEQLVAEKSVLHGPSRVMPQEYPHLTCRS
IDVGLPPAGGRPGLIDQLFTELITDTPDAVVAYRGQRRWVQTFEPVTLDQ-ES---SPLRPQGVYLITSGLSDTGLIFAHYLAQTVQAKLILMAPAPFPG
QAAWTSRKIEQLRA-IEALGAEVLVLSATET--IDIQAVVAQACQH-FGQLHGVIHIPATR-GGLMQLKTAEQAHQVLAPRVVDTQILETALQDIPDFLA
LFGSNVGVTG-GLGLVDECAANAFLDAYAHRRESAQPYPVIAIDWSGWHWDDHFEQLAAGAPQMLRETYGITPEEAGQAFELALSSAQPQIVSTRDLQTF
-----I-------------------------DEQNTL----TTSNV-----V--------RQQDTMQPIQS----LS-----EGDFVAPATEIEERVAAV
WQDVFGLERVGRDDNFFDLGGHSLLAIQLVSRLRDALQLDLPLSSLFETPTVAGLAALAADT----------
>tr|A0A0D8ZQK5|A0A0D8ZQK5_9CHRO Beta-ketoacyl synthase OS=Chroococcales cyanobacterium CENA595 GN=UH38_17145 PE=4 SV=1
--------------------------------------------YCTLIFIDKIGLGIEIARLQLEGQDVITVQEGAKFTKFDDRAYSLNPQQRDDYDLL
LNELIAQNTIPTAIAHLWNVTAFDN-TKIESVEQLQDKGFYSLLFLAQAVGRQTSQLQITVVSNNMQSVIGKDCLYPEKATLLGAVKIIPQEYAHISCRS
IDIVIPTDV-YEKLVDSLINELKTQSSDIVVAYRGVNRWVQTFEPVRLEKHK-E-TSKLKQGGVYLITGGMGGVGLTLASHLAKSIQAKLVLIGRSAFPA
KSEWISQKIRKLQE-IENFGAEVLAISADVSNLEQMQKVFTTVKEK-FQHINGIIHCAGVADAGRR---TREMTAEIMAPKVKGTLVINSLLKDIQDFFI
FCSSLSSVIYSKFSEVGYCAANEFLDTFAYYKTHIEGTFTVSINWNDWLDVGM-----SIE-AVTFLMDAVSPAEGVEVLERVL-NSVPQIVSTQDLTAL
-----I-------------------------ERDRDF----NPQA----------MLDSLKTTASATYPRP----QL-----TNAYVAPRNETEKIIAEV
WQNLLGIEEVGIYDNFFELGGDSLSIVKLHRQLQKRLQRDLFTTDLFEYPTINALAQYLSPA----------
>tr|M4T757|M4T757_9NOSO Polyketide synthase OS=Nostoc sp. 'Peltigera membranacea cyanobiont' PE=4 SV=1
--------------------------------------------GCWLIFIDECSLGEKIVRLTLEGNNAIIVRIGEQFSSEDRRVYTINPRRQDDYYAL
IKELNRLELTPNRILHLWNLTLNSGTETIESLERCETLGFYSLVFLAQALAEQTNPMQIGIVSNNLQEVTGSEVLDPGKAFILGPCKVIQQEYSNIACCS
IDIIIPETEQQEKLVDRLLAEFTVQLSDRVVAYRGNYRWVQTFEPVRLDRVVEA-KPQLRERGVYLITGGLGGVGLFNAEYLAKTVKAKLILIGRSAFPN
RDEWVSRKILKLQE-LEALGAEVLVFKADVTNREQMEAAITQANNR-FGQINGVIHNALED-KGQK---TLEIGRIVFTPKIIGTIILDNLFKNVEDFFV
LTSSQASVI-GGIGLVEYTAKNAFLDAFAYYSASKDGKFIKSINWDIWNTPEWMAKTKLYR-VAET---GLTLEEGMESFERILFSSMPQIVSKSDFNNL
-----I-------------------------NQKLIN----LKDT-------LNLEEESSVSRVKKTHSRP----DL-----RNAYIAPRNEIERTLTEI
WQEIFSIEQVGIYDNFFELGGDSLLATIVISQLRKTLKIEVPYKSFFDEPTITKLALVVEEI----------
>tr|K9XCC5|K9XCC5_9CHRO 6-deoxyerythronolide-B synthase OS=Gloeocapsa sp. PCC 7428 GN=Glo7428_1765 PE=4 SV=1
--------------------------------------------HCSLIFIDEYGVGSELVHLQQLGQEIITVKVGEKFHQLDRNTYAINPNQADDYYKL
LLQLREQGKTLKTITHLWSLTQ-----QILSWEATQNLGFYSLVYLAQAIVQQDT-IELLVIANYLYDITGNEKLYPEKATILGACKVIPQEYPNIRCRL
ADILLPTST--EDIIKQLLAELTAESEDLIIAYRNNYRWVQTFESVALESATED-KIRLRTDGVYLITGGMGGMGLTFAEYLAKTVQAKLILLGRSLPSD
----N----EKIKQ-LEALGAEVLVVAADVTNEEQMQSAIAQSLER-FGTIHGVIHAAGIA-AGLK---TPEIAEKVFAPKVQGTITLNNILKNINDFLV
LCSSLSAIQ-GGFGQVDYCAANIFLDAFAHWNTTRNNQFTIAINWNTWQQVGMAVNTDV---PDESLKNAILPAEGVEVFSRIL-ANLPQVVSTQDLQVG
-----L-------------------------EQLHQL----VLSL-------SLAQKPINCQVSASRHSRT----LQ-----ESTYVEPRNEIEQTIANI
WKELIGIEKVGVHDNFFELGGHSLLAVQTISRLREAFQVELPLRTLFDAPTVSELAHVIVEK----------
>tr|K9U3Y8|K9U3Y8_9CYAN Beta-ketoacyl synthase OS=Chroococcidiopsis thermalis PCC 7203 GN=Chro_3720 PE=4 SV=1
--------------------------------------------DCSLVFIDEYGLGSELVQLQQLGQNVITVKGGKEFNQLDSNTYAINPSQADDYLNL
LRQLREQGKTPKTITHLWSLHQ-----QTLSWETTQNLGFYSLVYLAQAIGQQDP-IQILVIANHLHDITGNEELFPEKTTILGACKVIPQEYPNISCRL
VDILLPTST--ENILEQLLAELTAELEESIIAYRNNYRWVQTFEPVTLEPTTED-NIRLRQQGVYLITGGMGGIGLVLAEYLAKTVQAKLILLGRSLPSD
----R----EKIKQ-LEALGTEALVLAADVTNEEQMHSAIAQSLER-FGTIHGVIHTAGVA-AGLK---TPEIAERVFAPKVQGTITLNNVLKNINDFLV
LCSSLSSIQ-GGFGQVDYCAANTFLDTFAHWNTTTNNSFTVAINWDAWQQVGMAVNTNV---PDESLKNAILPSEGVEAFSRIL-ANLPQVVSTQDLLAG
-----I-------------------------EQLNQS----VLSL-------SFAKKSVNCQVSASRHSRT----LQ-----ENTYVAPRNEIEQTVANI
WEELIGIEKVGIYDNFFELGGHSLLAVQTISRLREAFQVELPLRTLFDAPTVSELANVIALK----------
>tr|K9WUC0|K9WUC0_9NOST Polyketide synthase family protein OS=Cylindrospermum stagnale PCC 7417 GN=Cylst_1519 PE=4 SV=1
--------------------------------------------GCYLFFVDECGVGLQIIQLQQLGYDIIAIEASEQFNQLNSNTYTINPAKADDYQNL
LRQLGEQGKIPQTIIHLWSITQ-----ETLSWETTQDLGFYSLVYLAQAIGQQNA-IKLLVIANHLYEITGSEKLSPEKATILGACKVIPQEYPHISCRL
VDVLLPTSA--KDFVEQLLAELTDESESPIIAYRGNYRWVQTFEPILLEKPAED-KIRFRQGGVYLITGGMGGIGLVLAEYLAKTVQAKLVLLGRSLPSE
----DSPQMEKVRQ-LEAFGAQVLVLAADVTNQQQMQNAIAQALES-FKEIHGVIHTAGIP-GGLK---TPEIAESVFAPKIQGTLILNNVLKDINDFLV
LASSLSSIQ-GGFGQVDYCAANAFLDAFAHWNTSINSRFTVAINWDAWQEVGMAANTIV---PDESLKNAILPEEGVDAFSRIL-ANLPQVVSTQDLQTS
-----I-------------------------EQINKL---------------GLPQKSVKSQLSATRHTRT----LQ-----ASTYIAPRNQTEEIIANI
WQELIGIEKVGIYDNFFELGGHSLLAVQTISRLRENFQVELPLRTLFDAPTIADLATVIVEK----------
>tr|G6FSF5|G6FSF5_9CYAN 6-deoxyerythronolide-B synthase OS=Fischerella sp. JSC-11 GN=FJSC11DRAFT_1702 PE=4 SV=1
--------------------------------------------TCYLVFVDECTIGSQIVHLQQTGQDAIAVLVGAEFSQVNHNTYTINPTQKDDYYTL
LQTIHQQGKIPETIIHFWSLTH-----IHQSLETIQNHGFWSLIYLAQALGQQDSKIQLFVVSNHLYDVTGNEELLPAKATILGPCKVIPQEYPGIKCRQ
IDVVLPTSR--DNLVQELLAEITAESNESIIAYRNHHRWVQVFEPITLEKPTSR-KTRLRQKGVYLITGGTGGIGLEIAKYLAQTVQAKLILIGRSQLPA
KEHWTHHKIQKLQE-LETLGAEVLILPADVTNYEQMQSAVAQSLEN-FGEIHGVIHAAGVA-SGLK---TLEIVNSVFAPKLQGTLVLNEVLQDINDFLV
LCSSLSSIY-GGFGQVDYCAANAFLDKFAHFNTSKNGKLTLAINWDTWQEVGMAVNTAV---PEETLKNGLLPTEAVEAFERIL-ANLPQIVSTQELQLV
-----I-------------------------DQFNQF----LSSS-------FLNSKSENTHLSGTRHART----LQ-----ETTYVAPRNEIEQSIANI
WEELIGIDKVGIYDKFFELGGHSLLAVQTISRLRETFQVDLPLRTLFEAPTVAELAIVIAEK----------
>tr|F6AUU6|F6AUU6_DELSC 6-deoxyerythronolide-B synthase OS=Delftia sp. (strain Cs1-4) GN=DelCs14_2099 PE=4 SV=1
--------------------------------------------GCMLLLAEAGTLAESLAAWSDTPAPVVRIEPGPLHERLGPARHALRMTERSDWTRA
LGQIAAEIGPVACICDLWSLGTLDDA-------QAAERCLLGPLALAQALEAVAGRQQMLLVTDGLEDVTGTESLQPAKAMLHGPCLVIPQELPGMACRI
VDVLPVQSG-GM---AALAQRILAE-APACVALRGPHRWTRRYERIAGQTAPAV-TPRLRRGGCYLITGGLGGMGLALARHLAEHWQARLVLLGRSALPE
RGQWLRARLQQLLE-LERLGAQLCLVQADVGSEAQLRTALEQAQRA-FGGIHGVIHAAGLAGG-MLADKRAHEVMQVLAPKLQGTRALLAALA--PDFML
LCSSLAAVAG--LGRIDYAAANACLDALAVAGR-TAGWPLISVGWDGWRGVGMAAGTSMP------EGVGIAPEQGVHLFERILAGPQPHVVSTTDLETR
-----R-------------------------HADLA-----ELLDQA----L-PA---TTTAGPVPTQVRP----GG-----MAGFVAPEGDLETGLAAL
WSGFLGVAPVGAEDNLFELGGDSLMAIQLLARVRQAYGVEIHPAA-LRTPTVRRLAELVETR----------
>tr|K9X846|K9X846_9NOST Polyketide synthase family protein OS=Cylindrospermum stagnale PCC 7417 GN=Cylst_6459 PE=4 SV=1
--------------------------------------------SSWLVFIDDCGLGSQIVRLERDDCDVISVKVAAEFTQQSDRTYTLNPQQADDYNTL
VRQISAQREFPNTIVHLWSVTKNSQTIILEGVDKAQDLGLHSLIFLAQALGKHIHEIQLTAISNNVQPVTTEEELCPEKATILGAIKIIPQEYSSISCRS
IDIVLPKSGNECKLIDQLLNELQAKSSDLFIAYRGLHRWVQTFEPVRLNKPSET-KLRLREQGVYLITGGLGGVGFTLGEHLAKSLQAKLILLGRSAFPA
PEKWISRKIRKIQE-LEQLGAEILVVSADVANEEQMQAVIAKAQQR-FGSINGVIHTAAVV-YAVIQRRVKEMTESVLAPKVRGTLVLSKLLEHVEDFLI
LCSSVGVVLYTKFGEVSYVAANEFLDVFSYYNTCKNGTFTVSINWDDWQEVGMSVEAVKNA-VKKYLQNALLPSEGADVFMRILNSSFPQVVSTEDLTTR
-----I-------------------------KLNDS---------F-----S-KSFESLEVTISKTAHPRP----EL-----SNVYVAPHNELEQTISEI
WQQQLGIEKVGIYDNFFELGGHSLLATQVISRIREAVQIELSLNNLFEEPTVAGISAI-VEK----------
>tr|A0A0I9VPM5|A0A0I9VPM5_9BURK Polyketide synthase OS=Delftia tsuruhatensis GN=AA671_12420 PE=4 SV=1
--------------------------------------------QVALVFGDGSATAETLVALRAQGIDVVCVEAGAAPACLAPGRHAVRPGERRDCEDL
LDAVQAQFGPVDAIYHLWAMDAAAPA--------PLERGFHSVLALAQALEARRTRRLLLVAAGGSEDVTGAEALNPEMAAVFPLCKAIGQECPSIDCRF
VDVAQAGS--QARLARQLLDEARALAADTAIALRGAHRWRKTYEPLQWQD------PRLRRQGVYLITGGLGGVGLALARHLAAHWQARLVLVGRTALPA
RSQWLRQQLLQLLA-LEAEGAQVLTLAADVADAAQMQAALAQAHQR-FGALHGVVHAAGHADG-MLSTRTRDSVERTFAPKLRGTRLLLDLLGGQADFVL
LCSSISSLTA--LGKSDYAAANACMDALAALSR-QRAWPVISVDWDAWRDLGMAAGMRIP------EGIGWSGAEAAAVFERIVNGDPHQVISTTDLQQR
-----L-------------------------GEIDA-----GLVDAL----A-EEAFAEPGSQAGGGHPRP----AL-----QTAYVAAEGELQQALAAL
WTDMLGIAPVGVDDNLFELGGDSLLALQILGRVKKRFGVELHPAA-FKAPTVGELAVLVETR----------
>tr|H3SBB6|H3SBB6_9BACL Polyketide synthase subunit OS=Paenibacillus dendritiformis C454 GN=PDENDC454_04009 PE=4 SV=1
--------------------------------------------SLWVVFSPEDGIIPRLVRMREAGRDVVAVHPSDSFSPLNDWAYRIHPGEAEHYERL
LRTLTEAGRAPDRIIHAWLAAEAGEADIPSDENRALDRGYYSLLALARAIGSCQEELHLAVVTSYMQEVTGDERLQPEQAAAIGACLVIPQEYGHVRCRS
IDIADSLRQRQQALAERLHAEIAAPSDDLFVAYRGAHRWVQKYARLPAPAA----GTGLRKHGVYLITGGLGGIGLTLAEHLAKTVQAKLILVGRSGLDG
EGAA---KRGALDE-LERYGSEVLVCKADVCDEARMKQVAAEAVAR-FGAIHGVIHAAGIS-GALIQRRTRETDERALAAKVNGTRVLDRVLAGMRDFLV
LCSSLTTALG-GVGQAGYCAANAYLEAYACRKRAEGGTPVIAIAWDGWQAVGMAAAAEQEIAAIGPDKLTRLPEEGVAVFRQALACRRPQVVSTTDLPLR
-----V-------------------------HAARAS----TLHS-----------LMDKRDGTGPQAARS----DL-----GTAYAPPEDELEQTMADL
WRDYLGLDQVGLHDNFFELGATSLDIIQMNAKLQRALGREVAVVDMFTHPTIHSLAESLRRA----------
>tr|A0A0M1NJ26|A0A0M1NJ26_9BACL Polyketide synthase subunit OS=Paenibacillus sp. FJAT-22460 GN=AM231_21035 PE=4 SV=1
--------------------------------------------ATWLVFAPEHGVCSRLAGLQQAGHGVISVYPSDSFAKLNDQVYGIDPRQQEHYTRL
LQNLKEAGTIPERIVHAWLTEESIHTETASRSTRILDNGYLSLIALAQAMGTCQDELQLTVVTSGMQEVTGEERLLPEQAAVLGACLVIPQEYGNVRCRS
IDIADSLGQRPQALLGRLQAEIIAISADTFVAYRGLNRWVQTYVPIPVPAASEE-NSSLREEGVYLITGGLGGIGMTLAEHLAKTVRAKLVLVSRSGIGD
EADWLATQLRMFEE-LEQYGAEVLVCKADVSNEQQMEQAVARAIDR-FGTIHGVIHAAGTA-GALIQRRTREIEERALTAKVDGTRVLERVLAGRKDFIV
LCSSLTSVLG-ALGQAGYCAANAFLDAYAYRKRALDNTHVVAIDWDGWQTVGMAAAAEQEVAIAGPGKQTRLPEEGIAVFRYALACGLPQVVSTTDLSLR
-----L-------------------------HAARTS----SLQS-----------LVDGKGGLSRTTPRS----DV-----STPFASPEDELEQTLAEL
WRDYLGIDQVGLHDNFFELGATSLDIIQMNSKLQRSLQQEVSVVDMFSHPTIYTLAGLLRRV----------
>tr|A0A081P0N0|A0A081P0N0_9BACL JamP OS=Paenibacillus sp. MSt1 GN=ET33_11230 PE=4 SV=1
--------------------------------------------RTYLLFHDRYGLAEALSGLKSEGHDVVVVLEGGGFRQVEEDVFTIHPAQGRSYEEL
LHALAAQKRFPDTVVHLWNVVEPESEGIAQRYAWSQQLGLYSLMHLAQAIGMQAKRTDLIVLTGSLQWVAHEQVRSPERATLFGALRVIPQEYAQIRART
VDVSLADLASSGRLIRQLLQEIE-YGGDFVVAYRGMQRFTQIYEPVKLPEADP---AAFRDGGVYLVTGATSEIGLQLCEEIARTAKVSFVLIGDASFPA
AREWTAGIIKRIRA-LEQNGTPLLHASADLTDEAGLRDIVRQAEQR-FGMIHGVLFAQEPYGG-LIQLGDRERSERVIAPQALGLLALESLLRSHPELMV
VFSRTISFTG--VGLMDQCASHHFVDAFAKWHA-AAGGRTVAVNWGMWQDDVWVRKQTELPADIMQATFGITGAEGLEAIRRIAASGLSQAVSTQSIHDA
-----A-------------------------GNGWLH----AAGQG-----A----------ASDSRQGRADAYQAG-----DWVQEPPQTEAEHKIAAI
WETLFGIPGIGRRQSFFDLGGNSLLSIQLVARLRQAFHGDIPMDVIFQSPTIAELAESIAQT----------
>tr|H0U5B0|H0U5B0_BRELA Short chain dehydrogenase family protein OS=Brevibacillus laterosporus GI-9 GN=BLGI_540 PE=4 SV=1
--------------------------------------------QRWLIFQDKQGLGKQVRYAERLGLEVVTVVPGQTFSKIDEKVFTIDIMSEESYQEL
FKTLDIDNLLPDKIIHMWSIQHTDEQE---GDEQLEHYGLYSMLYIAKQLGIYQQKMEIIALSNNLQEISNEEILMPVRSTILGPLRVIAQEYPQIKTRY
IDVQLTDMLKSDRLLKKVLDEIL-STSDFMVAIRGTHRFVQKFEQTRLPEKKSH--PSFRDKGIYLITGATQEIGLSVSEEIANTVKASLILIGDPDFPV
MEQWIASKIKRIRL-LQQNCEQVRYHSAHLTDEEEMRQVIRSAEDS-VGRITGIVYAAERFSG-FIPLKSKDSCYQNIAQQVYGPLVLEKLIDHMNEFML
LFSRTFSLTG--VGQMDNCVANVFLDTFARYQT-AKGIPTIAINWGMWKNDNWIRSQTGMPLEMLQEQYGITAKEGTHVMNRILTSDYSQVVSTQDIHSA
-----I-------------------------HEFNQY----DTLQ------------------SSTYSHRANDRKQA-----ADTYVAPRDETERKIADI
WQDLFGIPAISTKANFFELGGNSLLSIQLVTRLRNTFYNDIPMDILFQSPTIVELAQAITMS----------
>tr|F8FI38|F8FI38_PAEMK JamP OS=Paenibacillus mucilaginosus (strain KNP414) GN=KNP414_04854 PE=4 SV=1
----------------------------------------------YLLFADQGGLAGALR-LVRRGCEVVMVLSGDGHGQERDGPFVLASDGPQAYEEL
LRGIRAFGRLPDKIVHLWNTDVHSKQGLQEDYQAAQRSGLYSLISLAQALGMQGQPVELIAVTSRLLQVAHEPVFLPERATLLGALRVMPQEYGHLRTRV
IDVEPGGAARGRMLLGQLANEIG---SDFVTAYRGPFRYIPSHEEVRLPAIGE---GIFRSGGVYLVTGAAGGMGLPVCEAVAREVQASFILLGDPSFPP
PEAWTRDTITRIRA-LEASGSRILYASPDLTDEHQTALVLQQAEAR-FGRMDGVLFASEPYS--LIQWKDPARTGETLAPHVLGLAVLSSLLRDR-GFMV
LFSRTISVTG--IGQLDLCAYGSFLDAWARAES-AAGVPVVSISWSMWQEDVWLERMTGIPQGILQTAYGLSAGEGVQVIEGLAA--LPQAVSTQDLEKA
-----R-------------------------HSWASL----HESDGT----L------------SSDAPSP----GG-----PAERTAPRNEVERTLAGM
WETMFGVSGIGIHQNFFELGGNSLHSIQLVARLRQTFHGSIPMDI-FQSPTIAELAEAVAST----------
>tr|S9U724|S9U724_PAEAL JamP OS=Paenibacillus alvei TS-15 GN=PAALTS15_16331 PE=4 SV=1
----------------------------------------------YLLLSDNCGVSETLK-LERFGNTVILAHSGD--LNDNDSRLVYNPAQSDSYERL
IGNIAYHRRLPNKVIHLGNLDADLSNNRYQSYENIQQQGLFSVVSLAQAIGLQFQDVELIVLTGNLLQIAHERVANPERATLVGALRVIPQEYARIGTRL
IDVDVADFSFSRRYVRQLAIEIS---LEFLVAYRGFHRYVQTIEGVRLPLSEQ---ISIRDGGVYFITGADGGIGLLMAEAIAKAVKAKLILIGESPLPD
ISEWTTKHIRSIRA-LEQNGSEVWYASASLADEVELKQIIVEAEER-FGSIHGMLIASEPYD--LIQLKDIQETTQRIVPYLVGLSVLASSLNNP-AFLV
LFSRTVAITG--AGQMDLCAYNWYADTFAKHRT-ATGYPTLSVNWSMWQEDVWLDRQKEIPPQMVQKQYGIAATEGIHALERMLA--LPQIVSKQNFQTA
-----S-------------------------QDWQSI----HTSPVI----I------------NSGAGET----HE-----EVSHSVPRNETEEKIAAI
WQTLFGISDIGVHRSFFDLGGNSLHAIQLVARLRHQFHGDIPMDI-FHHPTVAELAEAVSRS----------
>tr|A0A0P9E0P6|A0A0P9E0P6_9BACL JamP OS=Paenibacillus sp. A3 GN=QJ48_07450 PE=4 SV=1
--------------------------------------------RTYLLFHDRHGLGEALSGLKNKGHDVVAVLEGGGFRQVEEDVFTVHPAQGRSYEEL
LHALAAQQRFPDAVVHLWNVAEPESEEIAQRYARSQQLGLYSLMHLAQAIGMQAKPTELIALTGSLQWVAHEQVRSPERATLLGALRVIPQEYAQIRARA
IDVSLADLASSGRLTRQLLQEIE-HGEDFIVAYRGMQRFTQLYEAVKLPEADP---AAFRDGGVYLVTGATSEIGLQLCEEIARTAKVSFVLIGEASFPG
AREWTAKIIKRIHS-LEQNGSPLLYASADLTDEAGLRDIVRQAERR-FGAIHGVLFAQEPYGG-LIQLGDRERSERIIAPQALGLLVLVSLLRSHPELMI
VFSRTISFTG--IGLMDQCASHHFVDAFAKWHA-AAGGRTVSVNWGMWQDDVWVRKQTELPANVMQAQFGITGAEGLEAIRRIAASWLSQAVSTQSIHDA
-----V-------------------------GSGWLH----AAGHA----------------ASDSRNSRTDTHRDG-----EAPQEPPQTEAEQKIAAI
WETLFGIPGIGRGQSFFDLGGNSLLSIQLVARLRQAFHGDIPMDVIFQSPTIAELAESIAQT----------
>tr|A0A0C2LKV2|A0A0C2LKV2_9CYAN Polyketide synthase OS=Scytonema tolypothrichoides VB-61278 GN=SD80_11160 PE=4 SV=1
--------------------------------------------ERWLLFIDECGVGSELGRLEQSGKNVIVVKVGHQFTKLSEGIYVINPQNCDDYDVL
FQELIALGKTPHNIAYCWSISTLNT------LEQNEFLEFKILLFLTQSLNNQTNRLQIWVISNKIQEVNGNETLSPEKATVLGLCKVIPQEYSNITCRS
IDVVLTNRRCDSHIIDQIINEFRAKSSELVVAYRDRYRWVQTFESVRLESVVEE-KTPLRKQGVYLFCGGLESLGVVLAQYLVKTLQAKLIFIEEWAFPE
KHEYVSRKIQKLQK-LGDLGAEVLIVRADTTNYEQMYQSLA--PEK-IGEIHGVIYSTGRT-ENSIPEIGQTELEKLLDSQRQNLTVLEQVLEKRKDFCI
IFSSLSSILG-GFGLALYSGVNQLIDTFSQRHNQTRSLPWIVINWDKLQLNTTQEQK-----TLSGMELAITETESVEVFKRILSLRGTQVVSTVDLKAR
-----C-------------------------ERT-----------FHL--DSKLS--KFSQVNSSSSYSRP----NL-----SNSYVAPTNELEEQITEI
WQEVLGIAQVGIYDNFYELGGDSLIATQLVSRLRAKFPVELPLRDLLVQAMIPAKQAEMIEQ----------
>tr|A0A0M4T2E0|A0A0M4T2E0_9NOSO PscL OS=Nostoc piscinale CENA21 GN=pscL PE=4 SV=1
--------------------------------------------SIWLLFVDDLGVGEQILKLKNQGNTVVTVHQGDEFQKISTTSYQINPYSNSDYELL
IQELLSSGIQPENIAYFWSLSQIEN------SQPDKYLECKSLLSLIQSISKLKHHLQIKVITNNILEVNGNEKLNPEKSTILGLCQVISQEYPNITCQC
IDIVFNGDR-NNQIIDQISNELISTSLDNVIAYRDRHRWVQTFTPSHLDAIVDE-NTPFRNRGTYLFAGGLDNLEFLLAEYLTKTCQAKLIFIESSQFPK
QENFISQKIQHFIA-LEEIGAAVLLLRADKTNYEQMHQILA---KN-VEQINGVIYATGIK-EQSLPEITVAELENILKSQRHQITILEKVLQNYDDFCC
IFSSLTSILG-GFGLCLDAAVYQLLDSFGNQHNQNNSCPWYIINWDNIQLHTTPEST-----ITSGTTLAITATAIIEVFQRVLAIQGTQMISPVDINVK
-----K-------------------------TQIIN---------R-----N-SLETQSKQLDSSPRYSRP----SL-----NNSYIAPTNELEKQITEI
WQEVLGIKEIGIYDNFYELGGDSLIATQLVSRLRAKFPVELPLRDLLVEAMIPMKQAEIIEQ----------
>tr|K9QFB1|K9QFB1_9NOSO 6-deoxyerythronolide-B synthase OS=Nostoc sp. PCC 7107 GN=Nos7107_3486 PE=4 SV=1
--------------------------------------------EDWLFFVDDLGIGEQLAVLINQGKNVINVKRGEQFKQIDNSNYIINLYIKEDYDLL
LKEIISSGGNIQNIVYVWSLDYLNE---------SKYLEFNSLLFLTQSIGKLS-DLQLWVISNNIQQVNGYEQLEPEKATILGLCKVISQEYSHITCRC
VDIDLTNRQGYYESIAQLANELTSVSSDLVVAYRNSYRWVQTFEPIRVEAILEE-KTPLRQQGVYLFPGGLGDIEVAIAQYLATNFQAKIIFIEDENFPE
KDDFVSRKIERLLV-LEQLDPTVLVIRIDATNFS---------WEK-IGEINGVIYKTGIK-EDSISEIQDRESTDLFNFQHHHIRLLTQVLQNQNDFCV
VFSSVSPILG-GCGLSLDAAASYFLDTFINQHNCKNSLPWYIINWDKFNQAQQ---------T---SELAISAKEAVEVFQRIFTLEGTQVISPVDINTR
-----N-------------------------NQIFN---------PH----FFTN-SKSFELDSSSRYSRP----NL-----SNAYVAPTNNLEQQITEI
WQEVLGITEIGIYDNFYELGGDSLIATQLVSRLRAKFPVELPLRDLLLQAMIPAKQAEMIEE----------
>tr|A0A0D6YL79|A0A0D6YL79_MASLA Polyketide synthase OS=Mastigocladus laminosus UU774 GN=SP67_06205 PE=4 SV=1
--------------------------------------------TKWLFFVDDLGVSEELIALENQDNNIIIVKTGEKFEKKDECIYTINPCIDQDYHIF
FKELIALGKFPKNIAYFWSLNNYNN------YHSENYLEFQSLLFISQSLSKLDQSLQLWVVSNHIQEVDGNEIINPEKATVLGLCQVISQEYPQITCRS
IDIALTNYLYESKIIDQLLNEFTAVSSDLVVAYRGSHRWVQTFEPVHLTSAVEE-KLPLKKHGVYLFFGGLDSIEVVLAEYLIKNFQAKLIFIEDLDFPE
QYDFISCKIQQLQV-LENLSADILVIRADKTDEQQIRQIFL--SEN-IEQINGVISSTGIK-EKSIPEIGKIESKNLFDFQRRQITVLAQLLENINDFCI
VFSSLSSILG-GFGLGLYSAANHLIDTLINQHNQNNYLPWYTIKCDKIQLNFTPKSD-----TISGEKLAINPTETIEVFKRILSLDKTQIVSTVDIKTR
-----H-------------------------NHA-----------FNL--DYPAS--KYSQLYLSPRYSRP----QL-----SNSYIAPTSELEKQITQI
WQDVLGIAEVGIYDNFYELGGDSLIATQLVSRLRAKFPIDLPLRDLLLKAMIPAKQAEMIEQ----------
>tr|M4T9Q7|M4T9Q7_9NOSO Polyketide synthase OS=Nostoc sp. 'Peltigera membranacea cyanobiont' PE=4 SV=1
--------------------------------------------KEWLLFVDDCGVGVQLIRLEQHDKNVIVVEKGQEFRKLREGVYTINPQNRDDYDVL
FKELILLGRIPQNIAYLWSLNTFEN------RQLSKYLEFQSLLFLTQTIGKERDRLQIWLISNQIQEVNGNETLDPEKATVLGLCKVIPQEYPNITCRN
LDFVLTNRRFDSYIVDQIINEFIALSPDLVVAYRDRYRWIQTFDSVHLSAG-AD-KNILRKEGVYLFPGGLESFAVVLAGYLAKTLQTKLIFIEDSPFPE
NDEYVSRKIQRILI-LEELGAEVLVMRADPTNYEQMHQILG--SDN-IGQIHGVISSIGIT-ENSIAEIQKTELEKLLDTQIHKITILEKVLHNQKDFCI
ILSSLSSVLG-GFGLALYSGVNQLIDTFTQRHNQTTYFPWKIINWDKLQLNATQEEK-----ILSGVELAITETESIEVFKRVFSLAGTQVISTLDFKAR
-----C-------------------------EYASR-----MLRDRTFKGDSIAA--KFSQLDSSSHYSRP----NL-----SNSYVAPTNELEKQIVEI
WQEVLAITEVGIYDNFYELGGDSLIATQLVSRLRAKFPVELPLRDLLLQATIPAKQAETIEQ----------
>tr|K9WB71|K9WB71_9CYAN Polyketide synthase family protein OS=Microcoleus sp. PCC 7113 GN=Mic7113_1745 PE=4 SV=1
--------------------------------------------EQWLLFVDEWGVGSQLVKLEQNGKNVLVVKVGEKFTQLSEGVYAINPQNRDDYEAL
FQELIAQDKIPHNIAHLWSLNTFDN------RQLGKYLEFNSLLFLTQSLGKLNEYLQIWVVSNQTQEVSGNETLVPEKATVLGLCKVIPQEYPNITCRS
IDVALTNRQCDSPIIDQILGEFTALSSDLVVAYRDRYRWVQTFEPMRLESVIEE-KTRLRQQGVYLFPGGLESLGVVIAEYLAKTLQAKLIFIEDSAFPG
RDEYVSRKIRKLLV-LDELGAEVLVVRADATNYDQMHQSLA--PEK-VGQIHGVIYSTGIT-ENSISEIDSTTLEKQLDYQRHKITVLEQIIQNKNSFCI
IFSYLSSILG-GFGLALYSGVNQLTDTFTQRQNQTKCPPWLSINWDKLQLNATQEQT-----VFSGVELAITEIESVEVFKRILSLGGTQVVSTVDLKTR
-----C-------------------------DRLWRG----TQRHHTFNLDSLPS--KHSQADLSSRYSRP----NL-----SNSYVAPTNELEKQIAEI
WQEVLGIAQVGIYDNFYELGGDSLIATQLVSRLRTKFPVELPLRDLLLQAMIPVKQAEMIEQ----------
>tr|G6G0G1|G6G0G1_9CYAN 6-deoxyerythronolide-B synthase OS=Fischerella sp. JSC-11 GN=FJSC11DRAFT_4610 PE=4 SV=1
--------------------------------------------SCILLFVDECGLGNKLLQLQQQNYDVISVKVAHNFTRLNESEYTLNPQQPDDYDAL
IQELFKQQKLPKKIVHLWSVTPGCQQQDFEKVEQAQTRGFYSLLFLAKALARQNDDFEITVISNHLQPVTPTELVSPEKATLLGAIKVIPQEYANITCRS
IDVIIPANGQEQKLVESLLGELSISSCEKVIAYRGGNRWIQCFEPVRLEQVKSN-TPRLKQGGVYLITGGLGGIGLVLAEYLATQVKAKLVLIGRRAFPN
QQEWISCKIRKLQQ-LQQLGAEVLVLAADVTDLQQMQQAIASAYST-FGQLNGVFHAAGIV-GKAIDKITKTDCEQQFQAKVHGLIVLEKVLKNTQDFCL
LLSSLSSVLG-GLGFVAYSAANNFMDTFVHQHNQNHPVSWISVSWDSWQLETENQQS-----TSSVSEFAFNAQEGVEALQRILNYSFNHVVSTGELQAR
-----I-------------------------DQWID-------------------LKSFPQTNLLSLHPRP----DL-----QNPYVPLTNEIEQKIANI
WQEVLGIKDVGLYDNFFELGGDSLLIIQVRNKLLKTLNKNLSIADLFEYSTISALAEYLGEK----------
>tr|A0A0N1G4G9|A0A0N1G4G9_9ACTN 6-deoxyerythronolide-B synthase OS=Actinobacteria bacterium OK074 GN=OK074_3106 PE=4 SV=1
--------------------------------------------EPVLLFADA---AARL---TEHAGEVFTVAAGDAYARD---TWTVRPDSEEDHGRL
VADLLAEDRLPARVVHAWAAGQLPAERGIERFEQAQRTGLYSLIALVKALSAQTRPLQLDVVSAGAYAVPAEPEPASELVTLGVAARVVGQEHGNIGSRH
FDLPAPVDE-----LRTLAAELTGFRPEVAVTLRGATRWTADMAPVRADWTAT---SRLRERGVYLITGGLGEIGSTIARWLHEC-GARLALLTRDALPP
REGWTALRIVRLRA-LEAAGAEPFLVNADVADEAGLRAAVERVEAH-FGALDGVVHAAGLPSQ-AITAASVEQCQWHFVPKAHGQIVLEKVLADHPDFCL
LLSSLAGVLG--LRLLGYGAANHFMDAAAERRG-LDRTVWISAAWDVWQHHDEKRAL-----SASMDDKAIQPDEGLEVIRRLLTLRISHVVSTWDIGHR
-----L-------------------------DQWVRD----DRVARP---SA-------------GVAAEP-----D-----DAAAGLGDRDLTEQVTRM
VRHSLGTEDITPDGDIFEFGGDSLLIVKLLSDVREQFSVEVPLAD-LGEPTSRALAALVQER----------
>tr|X0N2L4|X0N2L4_STRA9 Polyketide synthase OS=Streptomyces albulus PD-1 GN=P354_30000 PE=4 SV=1
--------------------------------------------DPVLLFADA---AARL---TRHAGEVLTVTAGTDYARD---TWTIRPDSEEDHARL
VRDLLAEERLPDRIVHAWSTAPLPAERGKERFEQAQRHGVYSLIALVKAVSAHTHPLQLDLISAGAYALPAEPEPAAELAPLAVAARVIGQEHGNIGSRH
FDLPGTPDD-----LRTLAAELAGRRPEVATTLRGATRWIADLEPVRADWTAK---SRLRDGGVYLITGGLGEIGSTLAHWLRECPGARLALLTRDPLPP
RETWTALRMTRLRA-LAAEGPEPLLVHADVADEDALRTAVEQVTGH-FGALDGVVHAAGLPSQ-AITAASVEQCQWHFAPKAHGQIALEKVLADHPDFCL
LLSSLAGVLG--LRLLGYGAANHFMDVAAERRG-LDRTVWISAAWDVWQHHDEKRAI-----SASMDDKAIQPEEGLEAVRRLLTLRVSHVVSTWDVAHR
-----L-------------------------DQWVRD----ERIARP---TT-------------GGTAAA-----A-----ADG-AGGADDLTEQVARL
VRGALGREDMPLDGDIFEFGGDSLLIVRLLSDVRDQFSAEVPLAD-LGEPTPRALARFVQER----------
>tr|A9FNK2|A9FNK2_SORC5 Polyketide synthase type I OS=Sorangium cellulosum (strain So ce56) GN=sce8261 PE=4 SV=1
--------------------------------------------AHWLVFTDEEAIGSRLVRIERAGRRVTRVRSGERFERAAERSFTLRLDQPEDYAAL
LRDLGASAGPPTRVVHAFSLGDPRGPHDPGAFREAQRRGSASLLWLARALGQQ---AHLVALASGLHDLTGREALRPEHAPLLGVCRSVPLEYPHLRCRV
IDLEAPVPD-ADRVVERILAEARSDAADTVAAYRGHHRWAPAVEPVALRPAQA--APLLRERGVYLITGGLGGIGLRLADHLARTARARLILTGRSAPT-
-----DEQRARLLA-LEKAGAEVIALRADAADASQMRAAAREAIDR-FGALHGVIHAAGVAA-G---RLTADALDAELSPKALGALAIDEIARALKDFVL
LCSSITALSG-GLAHAGYAAANAFLDAYAQAR--RAGPYTVSVNLDRWRNVGMAARAEA---RLDVIRNGMSPEEGLQVFHRVLSQALPQVVSVRPLHGL
-----P-------------------------SDDEGA----ALARRL---GA-G-GAAAA-----RSHEPP----RR-----AGAAALSPEAITAQVTAI
WARAFGIDPIDPRKDFFALGGESLLALQILNRVREAFQVEVPLRAFFERPTVAALAERIHEA----------
>tr|S4YFD6|S4YFD6_SORCE Uncharacterized protein OS=Sorangium cellulosum So0157-2 GN=SCE1572_48225 PE=4 SV=1
--------------------------------------------AHWVVFADEAEIAPRIVRLERAGRRVTRVRSGERFARPAERAFTLRPDQPEDYAAL
ARELGADAGRPARIIHAFSLDG-----DTGAFQDAQRRGSISLLWLARTLSKL---AHLIALACGLHDLTGREALRPEHATLLGICRSIPLEYPHVRCRV
IDLEAAAPD-VDPIAARILAEARSDAGDPVVAYRGPHRWAPAVEPVPLKPAQG--AALLRERGVYLITGGLGGVGLWLSDYLARTVRARLILTGRSAPT-
-----DEQRLRLTA-LEQAGAEVVTVRADVTDAAQMRAAAREALAR-FGALHGVIHAAGVAG-G---RLSADALHAELAPKALGAMALDEIARSLRDFVL
LCSSVTALSG-GLARAGYAAANAFLDAFAQAR--RPGPYTVSVDLDRWRNVGMAARAEA---RLDVILDGMRPEEGQQAFHRVLSQALPQVVSARPLQGL
-----P-------------------------SDDEGA----ALARRL---GA-G-DAAADAAAAAGRDEPP----RR-----AGAAALSPEAVTAEVTAI
WSRAFGLDPLDPKKDFFELGGESLLALQILNRVRETFQVELSLRDFFERPTVAAVAQRIQAA----------
>tr|L8EHB1|L8EHB1_STRRM Beta-ketoacyl synthase (Fragment) OS=Streptomyces rimosus subsp. rimosus ATCC 10970 GN=SRIM_40558 PE=4 SV=1
--------------------------------------------DPVLLFADE---AARL---AAHAGEVLTVRAGTAYGRD---TWTLRPDSEEDHARL
IADLLAEERLPDRVLHAWSTAPLPAERGRERFETAQRHGLYSLIALVKALSEHTKPLQLDLISAGAYAVPAEPEPAAELVPLAVAARVIGQEHGNIGSRH
FDLPAAVDE-----LRTLAAELAGQRPEVATTLRGATRWIADLEPVRADWTAK---SRLREDGVYLITGGLGEIGATIAKWLRECPGVRLALLTRDPLPD
RAEWTSLRIQRLRA-LEDGGGEPLLVHADVADEDALRAAVDQVTAH-FGALHGVVHAAGLPSQ-AITAASAEQCEWHFVPKAHGQIALEKVLSGHDDFVL
LLSSLAGVLG--LRLLGYGAANHFMDAAAERRG-LDRTVWISAAWDVWQHHDEKRAI-----SASMDDKAIQPEEGLEAIRRLLTLRVSHVVSTWDIGHR
-----L-------------------------DQWVRD----ERIARP---TA-------------GAAAAV-----A-----DAE---AADDLVGQVARL
VRGALGAEDMPLDGDIFEFGGDSLLIVRLLSDLRDQFSVEVPLAD-LGEPTPAALARLVQER----------
>tr|Q83DF0|Q83DF0_COXBU Polyketide synthase OS=Coxiella burnetii (strain RSA 493 / Nine Mile phase I) GN=CBU_0788 PE=4 SV=1
----------------------------------------------WIIFANQSVLCEKTC-LLSMGENIIKIFPGEEII--TYNTFTINPAEKSHYEEV
LRKSVSTDEAHYVILHFWGVDSSEIKS-NLLNSTELYQGLYSGIFIAQALNRIHASIFWGMVTTHLYSVLGNEKINPLKSTVLSLSRVLPLENSNIRMCQ
IDVDSLMNEYANEVISQVVKNLSC--VANTIVLRHQKRWKPTYQEINVTEFSN---ITIDPQGTYLITGGLGGMGLAIAKWLSKNSGITILLLSRSVFPA
QNSWISEKIKQLKK-IVRKGCQVEILKGDIADYRQIKVLLSKVEKQ-TGPIRGIFHLAGISG--LTALKNIETVQAVLQPKIQGTWVLARLFRKKVDFFV
SASSLTAIAG--VGQIDYCAANIFLDHFLEQNPFKYCERLLTINWNAWRSVGMAANVAGA--KVLYAGNSVTPEQGIKVLNTFLR--YRQVVSRYQPEEE
-----I-------------------------KRIKRM----FQPEEKI--DL----------------SAA----NR-----MKPKESNQLNVFDVMGQT
WKAVLGVSKINKTDTFYDCGGDSLTMIQLIVALEKHFGITIILQD-IRETSFGGMVRFVEAL----------
>tr|A0A0C1T7N1|A0A0C1T7N1_9CYAN Uncharacterized protein OS=Scytonema millei VB511283 GN=QH73_41305 PE=4 SV=1
--------------------------------------------SCTLVFIDECGLGEALVRLR-QGQMAIAVRVGSQFGQIEENVFAVNPQQAQDYEAL
LQALHARQQFPDSMIHLWTLTPHSQIGDVEIFERVQVRGFYSLLFLAQALGKQGDRLQLIAISNHLHSVTAEEILCPEKATIMAALKAIGQEYPHVSCRS
IDVMIPD---AEKFVERLLEELTDASADVAIAYRRGQRWVQAFESVKLPKTNT---ALLRTGGVYLITGGLGNIGLVLAEYLAQSVKAKLILTGRSAFPA
KDEWINGKIRKIQQ-LEALGAEVMVAAADVANINQMQAVIERAELQ-FGRLNGVIHAAGVL-ERTIEKIETINCERQFQSKVYGLFVLEKVLQGREDFCL
LMSSLSSVLG-GLGSVAYAAANLFMDAFVHQQKQNNSIPWIGVNWDIWQFKNNKNIF-----TSSLAEFAIAPEEGIDALQRILSQDFEQVVSTGDLQSR
-----I-------------------------ERSIQV----K-----------HSEPDIPQESLSSAYSRP----NL-----PNCYVAPRDRLEQTIANL
WQQLFGIEQLGIHDNFFDLGGESINGMTFINQFQKQLGQIVHISAIFEAPTVAEFAAYLQKK----------
>tr|A3INX2|A3INX2_9CHRO Polyketide synthase type I OS=Cyanothece sp. CCY0110 GN=CY0110_07434 PE=4 SV=1
--------------------------------------------DCWLIFMDEYGLGNALIRLKSQQQEVIQVKMGTDYQKINNHQYIINPEVKEHYQPL
VEQLLASHKNP-IIAHLWTVNSV------QCFEESQALGYQSIIYLTQAIGQRMASLSIGVVSSQIQQVTGEEILCPEKATVLGPVKVIPLEYLNLTCRN
IDLVISDRC-EQPFVDQLITELTLSSSDSFVAYRGNYRWIENYEKITLEKNEK---SRLRSEGVYLITGGTGGIGLALAEYLAKTVQAKLVLLSRSANPN
NQE-------SINK-LEQLGSEVLVLQADVSNEQQMQEAFNKINHK-FGCLNGIIHAAGLL-KGEQ---NSDLSDPVFAAKVKGTLVLDKMCKNIQDFLY
LWSSVGTILG-EFGQVDYDAANIFLDKFVNQK---SDYFTAAINWDLWREIGLASNLSW--YKNENLKQGMATEEGIEAFSRILAEDKSQIVATRGIETM
-----I-------------------------EIFKPS----KSQ---------SLKQQETTSKNHSAYPRP----NL-----STSYVAPRNKKEEIISEI
WKTILGIEKIGIYDNFFELGGHSLLATQVTSRIQETLNVQITVRELFEHQIIAKLAEFLENS----------
>tr|K9ZNK8|K9ZNK8_ANACC 6-deoxyerythronolide-B synthase OS=Anabaena cylindrica (strain ATCC 27899 / PCC 7122) GN=Anacy_5461 PE=4 SV=1
--------------------------------------------VSWLVFVDNTGFGDAFCRLKTHQHKVIQVKIGNCFSQINEQVYTINPQIREDYEKL
FQKISQLGKVP-LIAHLWSLNPH------ESFEKSQELGLYSLLNLSYVIAKQTESLKIGVISSDIQIVIGDENIHPEKATVLGGCKVIPQEQPNITCRS
IDIVISK-L-ENELIDKLIVEIVADTSEDVIAYRNNYRWVQTFAAIPLEKTAT---KQLRQKGVYLIVGGLGGLGLGIAEYLAKTAQAKLALIGRSTLPE
KSAWSSQKIRKLQE-IEKLGAEVLVLSADVADEVQMRSAVTQINAK-FGAIHGVIHAAGVR-GGLK---TSAMIKAVFAPKVQGTLVLDTIFKDVPDFLV
FWSSIAAFTG-GYGNVDYVAAHTFLDRFAQCSSL----PTITINWNAWQEAGMAIQLQEKY-KLEILKNGITLEEGIEAFNRILVSGLSQVVTPQNMQET
-----M-------------------------TQYANM----G-----------VFADKLAKTTVKANYPRP----HL-----SNSYVLPRNQIEQTIADI
WQEVIGIEKVGIYDNFFDLGGDSLIGVRVINSIQEEFHIQLSTVSIFEAPTVSQLAQLLNPE----------
>tr|K9PIC3|K9PIC3_9CYAN 6-deoxyerythronolide-B synthase OS=Calothrix sp. PCC 7507 GN=Cal7507_2758 PE=4 SV=1
--------------------------------------------RCWLVFVDESGLGSSMVRLE-QGHSVIQVKIGGEFSRNSDRIYTINPQQQKHYEQL
LAEILVSESIS-YIAHLWSISFT-----------EQDMGFYSLLYLAQAIGNQTNSIHIGVVSSNIQDVTGTEIIYPEKATLLGACKVIPQEYANITCCS
IDVVPAS-F-ENQ----IITEIAAQSTDTVVAYRGNYRWLPTYTAVRLEKAQK---IPLQPKGVYLITGGLGGIGLAIAQYLAETVQAKLVLVSRSHLPS
KDEWTTSKIRQVQV-LENLGAEVLVLSADVTNAAQMQMVAERSQQV-FGHIQGIFHAAGVA-GGLK---TPEMAANVMAPKVTGTLVLEETFKDNNDFLV
LFSSLSSIVG-GAGQIDYCAANIFLDVFASYKASKTKTFTTSINWDAWQEIGMGVKTTEIPDVLETLRTGISSKDGLDSLSRILQSGLNRVVSTKDLQTV
-----L-------------------------KQKHD-----G-----------IHE----ELNPQKIQNSP----SA-----HERYLAPRNEIEQQIAQI
WQEQLGIEVVGVNDNFFELGGHSLLAVRLVSRLREIYQVELSLRTLLEAPTIAEVANAITEN----------
>tr|A0A068J4P2|A0A068J4P2_9BACT Putative NRPS/PKS hybrid synthase module B7B OS=uncultured bacterium PE=4 SV=1
--------------------------------------------GRWLIFSDGGRLAENIILLADGEREIIVVTPGDSFTATGAGEYCLQPGSHDDMAAL
FAALRQRDAVPETILHLWSAAPAATPD-DDGSGAALEKGFYTLLHLAQVLSERAEPLELVVVACGTHSVNGDETLYPQHAALSGLCRVIPQEQDRVRCRS
IDIEASNDGDQGKIARRIIAELSHAATDPVVALRNSGRWIPEFEAVTLDETAVP-PPGLRQNGVYLITGGLGNIGLQLGQYLARAVSARLVLLGRSELGP
RSDWLGRKILAVRA-LEDAGAEVLVLSADVADAAQMREAIEQVSAK-FGQIDGVIHAAGAT-QDMLRDLDRAACERHFLPKIRGVQVLDQALEGHSDFCI
LMSSLASLLG-GLRFAAYASANAFLDAFARSRAAGEGLSWLSVNWDGWQFGDPDSSDN----ST-VAGLA-TASEGVDVFSRLLQVKIPRLVSTSDLQAR
-----L-------------------------DQWTRP----QQKAAV----A-----DGLSGASSAGQSGP------------------DEGIEKRLCAI
WSGLLGVDGIAVDDNFFDLGGDSLLALQVTSRLRESRIADLSTATVLESPTIAELTRRILKQ----------
>tr|T2IRQ7|T2IRQ7_CROWT Malonyl CoA-acyl carrier protein transacylase OS=Crocosphaera watsonii WH 0005 GN=CWATWH0005_5575 PE=4 SV=1
--------------------------------------------QNCLILTDESELSNALISLQKSNQNIVTVSIGDEFTQIAEKQYIINPKSAEDYQKL
WKSLPQ---KPHKILNLWLNKKVEIF------EQCQDLGFYSLVYLSQTIGQQ-ETVTMTAIAEGLHDVIGTETLNPGKATILGASKVISQEFPNINCQT
IDITAHN-----ISINSLLTELLT-TEDTVVAYRGHHRWVQTFEPLPLAEAEK---IPLKQKGIYLIAGNFEGLGLVYAQWLKQTINAKLVLIGPKNLPP
QTEWVTRCVRQMQA-LGTGGTEFLFFNADLSNKEQVKEIIDQTIEK-FGKIDGVIHAGTMGDS-PLPRLTPEECDRQWKTKIKGLLVLEEVLQGHTDFYL
LQSSLSSVVG--LGFAAYAAANTFMDTFATQRNQTGSTPWYTLNWDACQLDDVSPE------KTALLDLAMTPQEVWDVSGRILAHAHPQIVSPGDLSTR
-----M-------------------------NQEIVP----PTFADR----E----AL-------SSYQRP----SL-----NTPYEAPRNDIEEQVAEA
LQELLGIEKVGINDNFFELGGHSLLAIQAISRLREEFQVELPMRKLFESPTVAGIAKLIEEN----------
>tr|B1WWV9|B1WWV9_CYAA5 Polyketide synthase type I OS=Cyanothece sp. (strain ATCC 51142) GN=cce_3080 PE=4 SV=1
--------------------------------------------QNWLILTDESKLANALINLQKYQQTVITVTIGEEFIEIDENQYSINPQNAENYQKL
WQNLTQ---KPQRILNLWPMKEIKTF------EQCQDLGFYSLVYLSQTIAQQ-EAIKMTVMTEGLQDVIGTETLNPGKATILGACKVIPQECPHIHCQT
IDITAHN-----LSINSLLTELLT-TKDAVVAYRGSHRWVQTFEPLPLAEVET---IPLKQEGVYLIVGDFEGLGLVYAQWLRQTVNAKLVLIGRKDLPP
QEQWITRCVRQLQA-LGTGGTEFLFFNADLTDKKQIKAIIAQATEK-LGNINGVIHAGTMGDA-PLPHLTPKECDRQWKTKVKGLLVLEEVLQGQPDFYL
LQSSLSSVVG--LGFAAYAAANTFMDTLATQRNQTGTIPWYSVNWDACQLDAMPQE------KTALLDLAMTPQEVWEVSRRIFACAHPQIVSPGNLSTR
-----M-------------------------NQEMRH----STPEDP----E----AL-------SSYHRP----TL-----NTPYEAPRNAIEKQVAEA
LQELLGIETVGIHDNFFELGGHSLLAIQAVSRLREEFQVELPMRKLFESPTVAGIAKLIEEN----------
>tr|L8LWI8|L8LWI8_9CYAN Polyketide synthase family protein OS=Xenococcus sp. PCC 7305 GN=Xen7305DRAFT_00002070 PE=4 SV=1
--------------------------------------------SRYLVFVDELGIGDRIIKLRDNGQTAIAVSQGENFSQN-KDTYTINPNNPEDYQKL
IQDLVTSGKIPQKIIHLWNIPPQIPNP---NPQLPNSLDFWSLIYLAQAIEQNQQKTQILVGTNNLYDIIGDETLAYEQADILGAIKVIPQEYSEIDARQ
IDLAISETD--DYNIEQLITEFTTDTKDKIVAYRQNRRWVQTFESISLTKNSPE-QSKLKPQGIYLITGGMGGIGLALAEHLARTVQAKLILLGRSEFPN
REHWTSQKICQLKN-LETLGAEVLPVTADVCERDAMEQAIALACNR-FGTINGVIHGAGVA-GGLK---TPAIAETVFAPKVTGTLVLNQVLQTIDDFLV
LCSSLTSIV-GGFGQADYCSANAFLDILAHHNR--NNCPTVAINWDAWQEVGMAKNTTV---PADNLQQGMLSGEAIEVFERAL-ASLSQVVSTQDLPTV
-----I-------------------------EQNNNF----LTQY-------M-----AQPENSASSDSRS----LE-----RKNYVAPSNEIEKTIAKI
LQEVIGLKGIGIHDNFFELGGHSLLAVQVTAQLREIFQVDLSLQTLFEAPTIAQLANIIINQ----------
>tr|K9XVV6|K9XVV6_STAC7 6-deoxyerythronolide-B synthase OS=Stanieria cyanosphaera (strain ATCC 29371 / PCC 7437) GN=Sta7437_2670 PE=4 SV=1
---------------------------------------------SYLIFVDSSGIGKQLVQLRQNGTEVSTVYCGDKFSQH-DHNYKINPTNPEDYHSL
LKAISLTSNLPTKIIHLWSLSPHL----------PYNQSFYSLIYLAQALEQQKHKIKIVVGTNSLYDIIGNETLFYEQATVLGALKVIPQEYTYLDCRQ
VDLVIPESE-------NLITEFTTDTKDKIVAYRGNRRWVQTFEPIPLAKNTQE-KSKLRQEGVYLITGGMGGVGLVLAEYLARTVQAKLILLGRSQLPS
QETWISQKITKIRD-LEALGAEVLTLTADICDRAQMQNAIAVALKR-FGKINGVIHAAGVA-GGLK---TPEIAESVFAPKVTGTLVLNQVLAGIDDFLV
LCSSLSSVV-GGFGQADYSGANAFLDVFARCNH--SNCHTVAINWDAWQEVGMAVNTEI---PPDNLKNGLLSAEAVEVFERAL-VSLAQVVSTQDLATA
-----I-------------------------EQNNNF----LATY-------T-----TQPDSNYQ---------HL-----SKNYVAPSNKIEKTIAKI
WQEVIGFEKIGIHDNFFELGGHSLLAVQVTSRLREAFNLDLPLRTLFEAPTIAQLADAIADQ----------
>tr|A0A0M4SLG8|A0A0M4SLG8_9NOSO PscB OS=Nostoc piscinale CENA21 GN=pscB PE=4 SV=1
--------------------------------------------DCWLVFIDACGIGNQIVLLQNERQNVITVKIGKEFSQISYGEYTINPHSRNDYDTL
IKQLHNLGQIPHKITHLWNITSYNNQIDLENFAATQDISFWSLLFLIQALGEQTKPVAINIVSNNMQQVLDEEYLCPEKATILGLCKVIPQEYAHISCRS
IDITIPLVNQRQQLINNLYRELQTVASEQVIAYRGNQRWIQCFEPLPIASQTST-NNKFRNRGVYVITGGLGGIGLAIAEHLAKTVQAKLVLIGRSEFPK
KVDWLKTKIKKLQL-LEELGAEVLVLKADVTNLEQMQSAINQVCDR-FGKIHGVIHAAGTP-AGLK---TPELAAKVFQPKLQGTIVLNTVLQNLNDFLV
LFSSTTAIT-GGLGQVDYCAANAFLDGFAHNNFYQHQIPTISINWDWWEWDSWQKSLLAFAPNMKY---GISFAEGIDAFERIL-SQLPQVVSTKNLQTV
-----I-------------------------AEHQAF----A----------VPFLKNSASPQSQTAHPRP----IL-----ETAYLEPSSAVEQKIAEI
WQELLGIDQVGVDDNFFDLGGHSLIATQIVSQLRQDFQVELSLRHIFEAPTVAELAVVIEDI----------
>tr|A0A0C2LK67|A0A0C2LK67_9CYAN Uncharacterized protein OS=Tolypothrix campylonemoides VB511288 GN=SD81_21600 PE=4 SV=1
--------------------------------------------HCWLVFIDSCGVGSQIVQLKGKHQNVITIKIGEQFCQIGDWEYTINPQSRDDYDAL
LKTIRNLGKIPNKITHLWNITPYNDVTPIEYFEAAQDISFWSLLFLTQALGEQTNSLQISVVSNNMQQLLDEDYLCPEKATILGACKVIPQEYSHISCRS
IDITLPQTGQWQQVIDNLLVEITTTISEQVIAYRGNQRWVQYFEPLPIENQTVS-NTKLRKGGVYLITGGLGEVGLVIAEHLAKTVQAKLVLIGRSGLPP
KAEWQSKKIKKVKL-LEELGAEVLVLTADVANLEQMQSVIDRVGDR-FGEIHGVIHAAGTP-AGLK---TTELAAKVFQPKLKGTLVLNAVLQDLNDFFV
LFSSNTAIT-GGIGQVDYCAVNAFLDAFAHYNFYQQKIPTVSINWDWWQGNNWADSLMSAIPGLKY---GITFTEGVDAFNRIL-SILPQVVSTQSLQTI
-----I-------------------------ERVNSF----A----------TFSHKESSSNLSTDKHPRP----IL-----ETVYVEASNAVERKIADI
WQELLGIEKVGIDDNFFDLGGHSLIATQLVSQLRQDFQVELSPRHIFEAPTVAELALVIEDM----------
>tr|D8G9D1|D8G9D1_9CYAN Polyketide synthase type I OS=[Oscillatoria] sp. PCC 6506 GN=OSCI_4080017 PE=4 SV=1
--------------------------------------------QSWLVFIDGCGIGSQIVRLEKENQDVIVVRVGEKFSQLREWEYTIHPQNKDDYNAL
IKVLSDLNKIPQIIAHLWNITSNDRIHALEDLEETQVFSFYSLIFLAQALGEKSDSIEIAVVSNNLQELTDEGELYPEKATLLGPCKVIPQEYSNITCRS
IDITLPESGQWEQLIDQLLAELAVELSYPVIAYRGNRRWAQCFEPLPVKDKTLR-TPKLRQGGVYIITGGLGGIGLAIAEHLAKIAQAKLVLIGRSGLPP
KSEWLSTKIEKVQL-LEELGAEVLVIKADVANLEQMQAMVKQVCVR-FGDIHGVIHAAGVP-AGLK---TTELANSVLEPKMKGTLVLDAVLKDLKDFFV
FFSSFTSIY-GGFGQVDYCAANAFLDAFAHYKFARHQVLTVSINWDWWQWDSWQDALLSFEPQMKY---GITFQEGIEALGHIL-SCLPQVVSTRNLQAV
-----I-------------------------EQHEDF----ELTT----------LLEKSKDRPQSIHSRP----NL-----KTAYIAPSNDTEYRIAGI
YQELLGIDSVGINDSFFDLGGNSLIGIQLISRLRQDFQIELSIPSLFQSPSVAELAFVIEEI----------
>tr|A0A0D6YFV4|A0A0D6YFV4_MASLA Uncharacterized protein OS=Mastigocladus laminosus UU774 GN=SP67_20355 PE=4 SV=1
--------------------------------------------SSTLMFIDECNLGCQLVKLQQHNQDVISVKVGSEFTKLSDRLYTLNPQQPDDYDAL
LNELLTQEKFPEKIVHLWSVTSIGDTIGLEGLDKAQDIGIYSLLFLTQVLVKQTNEFQITVVSNNMQPVTGEEVLCPEKATILGAVQVIPVEHSNINCRS
IDVVLSSSGQEEKLVDQLLTELTTQSSDSVIAYRGVHRWVRTFEPVKLDKAIKG-KSRLREEGVYLITGGLGGVGLVVAEHLAHTVHAKLILTGRSAFPE
RDKWISNKIQKLLA-IEALGSEIQVVSADVANLEKMQEIITQAEKR-YGQINGVIHCAGVV-YAVIFRRSREMTESVMAPKVNGVLVLDQILKNVEDFLI
LFSSLSSILNTKFGQVGYCAANHFLDAFAYHKTYKDSIFTVSINWDDWQEVGMSVEALKRFNIAILQKNSLLPSEGIDVFTRILESEFPRVVSTQDLKIL
-----L-------------------------EQDRVS--------N------ILSLKVAEPTLSKPTYKRP----QL-----SNPYIAPTNETEKIIANV
WQNVLGIEQVGIHDNFFELGGDSLIGVQVISQLNKELNMKIPAVSLYQSPTVSSFAKTLNTE----------
>tr|K9ZQZ9|K9ZQZ9_ANACC 6-deoxyerythronolide-B synthase, Phenylalanine racemase (ATP-hydrolyzing) OS=Anabaena cylindrica (strain ATCC 27899 / PCC 7122)
--------------------------------------------SSYLVFLDECGLGWQLVRLQQQGHDVITVQVGTEFEKLS--SYSLNPQSSDDYDAL
VQQLLLKQQLPHTIVHLCNVTLDP-----EVINEWQTTGFNSLLFLAQALGKHMGEYRLVVISNHLQSVVGDEILSPQKSTLLGPVQVIPQEYPNFNCCS
IDIVLPVAGQYEKLLENLLTELRVASSEQLIAYRGVSRWVQTFEPVRLEKAKDE-TPRLRPGGVYLITGGLGGLGLVLAEYLAKTVQGKLILTGRSAFPQ
RDEWITATIRKIQE-LETFGAEILVVNADVASLAQMKKAIACGQLQ-FGTINGVIHAAGVP-GGVMQIKSIEEAHKILSPKVTGTLVLENIFQDVQDFLV
LCSSIAAIKG-IFGQVDYTAANSFLDAFARHKNSKNSTFTVAINWDAWQQVGMAAKASQQLVST-QTSAGLLPSEGIDAFVRILSSKLSQVVSKNDLHQT
-----E-------------------------QQLINH----Q----------AEFLATLEINLSQPAHPRP----LL-----SSAYIAPRHEHEQTLINI
WQEILGVSRIGINDNFFELGGDSLLAVRFISQVREKLRIELPINSLFAASTVADLAKYFERE----------
>tr|A0A0D6YFB2|A0A0D6YFB2_MASLA Polyketide synthase OS=Mastigocladus laminosus UU774 GN=SP67_20345 PE=4 SV=1
--------------------------------------------KQWLVFVDEHGVSLQLVKLKQKGKDVITVKVGKRFTKLSEGIYTINPQNRDDYDAL
LKDLIALSKTPQNIAHFWTLNTWDN------YQTSEYLEFNSLLFLAQTLGKHTNRLQIWVVSNQIQEVNGDEKLNPEKATVLSLCKVIPQEYPNITCRS
IDVVLPQSDQEEKLIDQLLSEFMASSSDLVVAYRNRYRLVQTFEPMRLEPAVEE-KIPLKKQGIYLFTDGLEGIGVALAEYLAQTVQAKLIFVENSILPE
KEQYISRKIRKLQA-LEELGAEVLVVFADVNNYKQMYQNLT--PEK-IGQIHGVIHSSEKI-ENSIQETDKIDLEKLLHFKCYSICVLEEVLQGRQDFCI
ILSSLSSVLG-GFGLAAYSAANLFLDVFTRRHNQTDTLPWLTINWDRWQRDETKKQQ-----TFYETELAITQTEGVEVFKRILSLGETQVVSTVDLKAR
-----S-------------------------DRS-----------FKL--ESLPTNPSPSQWNSSSRYSRP----NL-----SNPYVPPTNQLEKLIAEM
WQEILGIEQVGIYDNFFELGGDSLIATQLVSRWRATFPVDLPLRDFLLQASTVAKQAEMIEE----------
>tr|A8ZKN3|A8ZKN3_ACAM1 Polyketide synthase type I, putative OS=Acaryochloris marina (strain MBIC 11017) GN=AM1_A0231 PE=4 SV=1
--------------------------------------------TCDLVLIHDGGFVNDLIHLEQQNPNLIFVQPSTAFAQLNDRFYTVNPQSSDDYQTL
IQTLVSQHKRLQKIVHLWTLSTSEKPNDPELVQRCQFSGFYSLLFLAQALAKQSDGIQITVISNYLQSVTGNDPLAPEKSLLLGPIRVIPQEYPTIHCRS
IDINLPSPNQAERLTGQLLHDICCPITEPIIAYRGHQRYVQAVEKIRLDEPSKE-DSHLRQNGVYLITGGLGHIGLTLARYLAESMQAKLILMGRSTLPE
KGEWISRKIRQIQA-LEALGAEVLVVSADVSNEAELRSAISQAESQ-FGAINGVIHGAGLV-AEAISQLDLVTCEQQFQPKVYGLLVLEKVLNDKPDFCL
LLSSLSSVLG-GLGHASYAAANLFMDALTHYHNQTHSSPWISINWDAWNQDSDTEKM-----AFSLAQFSIEPDEGIRALQQILLHPQSQVVSTADLSAR
-----I-------------------------DQWIRP----KAIGKK----L--------ALESSHSHERP----TL-----STDYIPPEHKAEKILADI
FQQVLGVKPIGIYDSFFDLGGDSMIGIQLISKIRSHFQIELSIQHLFEAPCIADLAFNIEAL----------
>tr|H1XP65|H1XP65_9BACT Beta-ketoacyl synthase OS=Caldithrix abyssi DSM 13497 GN=Calab_2570 PE=4 SV=1
--------------------------------------------QNWLILKDDTGLARNFVFILKEPLKLTTVEPGTAFHDQGENKFAMPIDHKESFEKL
FEQLKASDRLPQHIVHCWNINASSQSS---ILDEAFISGYLSLLYLVQTLQKVTQPLTLTIVTNHLFQVTGYDAYAPLKAIILGLSKVIPQEFPNISCKI
IDLKLPHDVSLEPMSQNLIQEVFAHTDDPVVAFRARDRWTLEFRRIELPQSNPL-HGYLKNEGRYLITGGLGRIGLRLAHYLSRQVKARLALLEVADFPQ
ETSWVSQKIKTLQT-IKENGSEILILKADITDAASVQQAVSRAEER-FGGLDGVIHAAGLV-EQPIPELTREDLEAQLGPKLVGALNLRRALHQKTDFVL
LQSSVSAILG-GYGFGAYAAANAGLDALVYLQNQDSNSNWLSVNWDGWNFDETMPSANQ---AQEVARLALTPEEGLAAFERIFANPFGQLVSTGDLHQR
-----I-------------------------ARWVKG----VQK-------------EETDDKEKAMHDRP----EL-----PYEFVAPQNELQEEIAVV
WRKLLGIQNIGINDNFFDLGGNSLMGTQLISELRAKFQVELPLRALFEDATISGVAKIIEQE----------
>tr|A0A060Q3I1|A0A060Q3I1_9NOCA Putative polyketide synthase OS=Nocardia brasiliensis PE=4 SV=1
--------------------------------------------GPYLVFTDPETCSAELAHKALGGADVVTVSPGTEFA--TAGGYQLRPGAADDYAQL
TTALADRNLLPRTVVHLWSVQGPQ---SVHGVGAHQRLGFDSLLTLSGHLSRHVDGCRILVVTDHAQSCDAEDELYPGKTTLVGPALTVGQEYPGLAVRT
FDVRTPVED-WSELAESVVAELD---SAAVVARRGRRRLVQRLQPRTL---A----AYVRDGGVYVITGGTGSIGLQMAAHLAAAGSGLFVLLARTPLPD
LDDPE--RAVAVRE-LVRAGAQVLVLPCDIGDRAAASAAIALARKR-FGPIDGVIHAAGLLTD-TIENTTPELVAAHFRAKVDGTLALAHALRDERDFVV
LLSSMSAVLG--IGFTAYAAANAFQDQFVTLRGLPGGSAWRTACWDTWQATRQGEKP-G---VASLDTYSFAPADALAVFDRLIAGGR--AVSA------
GQLERL-------------------------EAWVP---------AG----DPF---D-----------------SG-----VVPAAATVEDYRRELARL
WQAALGVDQVGLHENFFESGGNSLVGLQLINAINKQFRVVVPTVA-FEAPTVDEMAGYLLTA----------
>tr|A0A0F5YFU1|A0A0F5YFU1_9CYAN Polyketide synthase OS=Limnoraphis robusta CS-951 GN=WN50_13390 PE=4 SV=1
--------------------------------------------KCWLIFVDEIGLGEKIVRLIAENQVVAEVRIGEKFIQLTETLFEINPEKFDDYQYL
IKILKQNNFVPNEILHFWGTESAEHFNLEIDFESYQNKSFYSLLALVQAITQQDTLVKLTTVTNNIHDVLGTEAFNPAQVTQLGLCKVISQEYPHITCKN
IDVALPENS-FTKGIDQLIAELQQ-YTEPVVAYRDRYRWIQTFESVLLPEHSA---TRFIKNGVYLIVGDLEGLGLVYAQYLTQELEAKLILIGRSTLPE
KHQWISKCIRKLQA-LETSGAEFLFFSADLADETKMQSIVTQAYEK-FGQINGVIHAGTMGDS-PLQDLDLEKCHNQFQMKVIGLITLAKIFEGQKDFYL
LQSSLSSIVG--VGFGAYTAANLFMDAFANQQNKTSSTPWISVNWDACQWDESTSQ------KTALIDLAIKPDEVWQISKRILSENISQLVSPRDLHAR
-----I-------------------------EQSIQQ----KTYENS----E----ILQLADQLNSNHARP----HL-----QTDYSAPRNEIEQIIANA
MQDLLGIEKVGIYDNFFELGGHSLLAIQIISRLREKFQIDIPMRELFESPSVAGIAKIIEEN----------
>tr|U7QE17|U7QE17_9CYAN Short chain dehydrogenase family protein OS=Lyngbya aestuarii BL J GN=M595_4603 PE=4 SV=1
--------------------------------------------KCWLIFVDEIGLGEKIVRLTAENQVVAEVRIGEKFIQLTETLFEINPEKFDDYQYL
IKILKQNNFVPNEILHFWGTESADHFNLEIDFESYQNKGFYSLLALVQAITQQDTPVKLTTVTTNIHDVLGTEPLNPAQVTQLGLCKVIPQEYPHITCKN
IDVAVGKNS-FAQVIDQLIAELQP-STEPVVAYRDRYRWIQTFESVLLPEHYA---TRFIKNGVYLIAGDLEGLGLVYAQYLTQELEAKLILIGRSTLPE
KHQWISQCIRKLQA-LETSGAEFLFFSADLADETKMQSIVTQAYEK-FGQINGVIHAGTMGDS-PIQDLDLEECHHQFQMKVRGLMTLAQIFEGRKDFYL
LQSSLSSIVG--VGFGAYTAANLFMDAFASQQNKTGSTPWISINWDACQFEESSSQ------KTALIDLAITPNEAWQVSQRIISQDISQIVSPRDLHAR
-----I-------------------------EQSILL----KTSENL----D----TSHSTEHLTSNHARP----HL-----KTSYTEPRNEIEKIVANA
MENLLGIEKVGIYDNFFELGGHSLLAIQIISRLREEFQIDIPMRELFESPTVAGIAKIIEEN----------
>tr|A0Z9T4|A0Z9T4_NODSP Malonyl CoA-acyl carrier protein transacylase OS=Nodularia spumigena CCY9414 GN=NSP_27060 PE=4 SV=1
--------------------------------------------QRYLVFCHGGGVGEKLVQLEKIGQDVITVKPGERFTQAGD-NYTIALDHPEDYKTL
WLQLQTDDQLPDVILHSWTLQELTNF------QQQQNLGFYSLLWLIQALSSS-PSVRICVLTQQVHNVLGNETLNVDDATILGLVKVIPQEYPNLTCQH
IDVSIPN-----LNLQQIVREITTRGLGSAIAYRGKTRWLQEFTPISLPDAEV---LPLISGGVYVIAGDLEGLGLIYAKFLSATVKAKLVFLGRSDLPQ
PKLWVSHCIQQLQA-LQAQGCEFLFNSVDLAQIDQVEEAIAHSLTQ-FGTINGVIHAAAMGDA-LIRNLTMDECEKQFSPKIHGLLTLEAALKNQPDFFL
LQSSLSAVVG--IGFAAYAGANCFMDAISHQHSQNSNTPWISINWDAVSLAITT--------PTALVDLAMTPQEVWQVTQRILAQPAAQIVSPIDLESR
-----P-------------------------QSQIPE----NS-------------------ISASNHARP----QI-----STTYVSPSNEIEARVTQV
MENLLGISPIGIHDNFFELGGHSLLAIQAVSQLRSEFQVELPMRQLFESPTIAGIAKIIREN----------
>tr|Q8YTS8|Q8YTS8_NOSS1 Polyketide synthase type I OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=all2635 PE=4 SV=1
--------------------------------------------QRYLVFCHAGNAGERLVHLQETGQEVVTVKPGEGFTQEGD-NYAIAPHNPEDYKTL
WLQLQTDDKLPDVIIHSWTLQERTNF------QQQQNLGFYSLLWLTQALSSS---LSIYVLTQQVQNVLGNENLNPDDATILGLVKVIPQEYPNLTCQH
IDVSISD-----INFQQLVREINIKGLRMSVAYRGKTRWIQEFQPISLPE--P---LPLITGGVYVIAGDLEGLGLIYAKFLAATVNAKLVFLGRSDLPQ
PKEWVSHCIQQLQG-LQAQGCEFLFTTVDLAEISQVEDAIAQALTR-FGKINGVIHAGVMGDA-LIRNLTIPECEKQFHTKIHGLLALETALKNQPDFFL
LQSSLSAVVG--IGFAAYAGANCFMDAIAHQRTQNSNTHWISINWDAVSLAITT--------STTLIDLAMTSQEVWQVTERILAQPAAQIVSPVDLASR
-----Q-------------------------QSQPLE----Q---------------------STTNHARP----QI-----TATYLPPSNEIEARVTQV
MESLLGIAPIGVNDNFFELGGHSLLAIQAVSQLREEFQVELPMRQLFESPTIGGIAKIIIEN----------
>tr|A0A0F7BLM5|A0A0F7BLM5_MYXFU Polyketide synthase OS=Myxococcus fulvus 124B02 GN=MFUL124B02_19445 PE=4 SV=1
--------------------------------------------RVWLVFEDEASPTDALLAAPGEERRVLRVRPGTAFRRTGDSEFTVAPGSLSDFRAL
LGALRDAGLLPDAVLHLWSLTPGLP----TSFAQAQASGYHSLVALARALIEHEKPCSIWVVTNNVHEVTGDEALSADKATVLGPCQVVSQEQPFLRLRH
VDVVTDADFLAPASLQSLRAELRSTALDTMVALRGPHRWVRTLEPLPLPDATGA-QVLSRPGGVYLLVHGLSGVGAMNARLASISPGAKLVCLEPSDLPS
REHWLSQRIRRARQ-LETLGAEVVVLSVDVTRQESLREAVDAALAR-FGALHGVVYGAWLP-EQLVSETGPDESAWHFDARVRGLALLDQVLGERPDFRV
VASSISSVLG-GMATVAHTAASAWQDTFAQA-ATRAGRRWVSLDWDVVRVEDYGAHP-----GAALDRLAIAPEQGAEALARVLSQTGAWWVSTHDPVAR
-----Q-------------------------ARPRAV----E--------------AVDSTPAARPQHPRPS---NL-----RSAYVAPTTEMERTLTEL
WQQTLGVAPIGIQDNFFELGGDSLIAVQLSDRLKRRLDISVPASSLYEGVTVKALAALLQPP----------
>tr|L7UBF3|L7UBF3_MYXSD Polyketide synthase type I OS=Myxococcus stipitatus (strain DSM 14675 / JCM 12634 / Mx s8) GN=MYSTI_03596 PE=4 SV=1
--------------------------------------------RVWLVFEDAASTADSLLPEPGAEQGVVRVKPGTGFQRHNDTDFTMAPGSQADLREL
VTTLRESGRLPDAVLHLWSLTAEPS----ASFAQTQASGYHTLVALSRVLVELERPCTVFVVSNHVHDVTGDEVLSADKATVLGPCRVIPQEHPHLRFHH
VDVVTEAGVLSPASLQALRTELRAAPREAVVALRGAHRWVPVLESLPLPEAPAP-HPTARAGGVYLLVHGLGGVGAMNARLAKLSPGAKLVCLEPVGFPA
RDAWQAQRIRRARE-LEAMGAEVHVVSVDLTNEEALRAAVDSTVTR-WGALHGVVHAAWLP-QKLVSETGPDETAWHFDPRVRGLALLDTVLGDRPDFRV
VASSISAVLG-GISTVAHTAASAWQDAFAQA-ATRAGRRWTSVGWDVVRVEDYGAHL-----GAAIDRLAVAPEQGAEVLDRMLAHAGPWLISTHDVKAR
-----Q-------------------------APPQPL----P--------------AQ--EVVARPLHPRPS---NL-----RSAYVAPTTELERLLADL
WQQMLGVTPIGIQDNFFELGGDSLVAVQLTDQLKRRLNLSVPASSLYEGVTVKALAALIQPP----------
>tr|A9AV06|A9AV06_HERA2 Beta-ketoacyl synthase OS=Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785) GN=Haur_3962 PE=4 SV=1
--------------------------------------------HTWLLLVDDSGLGLVLARLKQHGQTVVTIAPGAAFAAIDPASYTVRPAEREDYISV
IKKLAREGIEPSRVLHLWLASPAESAGSPAEVDGILERGFYSLLALTQALGNQ-ERCEVNVVTTGVHAVVGQEAVNATKSTVIGPCKIIPQEHPNLTARS
IDVIWAPDRGCEELVDRLVVELASTPTGVVIALRGQHRWVQAYEQIHLPEFSHP-HARLRDQGVYVITGGLGGIGLALAEYLVASVRAKVVLIGRTALPS
RERWTGHRVHCIRQ-LEASGAEVLVLQADVADAGQIAAAIDQAVAR-FGAINGVFHAAGVP-VGLMQLKTAEAAASVLAPKVQGTLAIAQAVRSLPDFLV
LFSSVAAAAGGGQGQADYCAANIFLDSYAQLH-HRDNGVTISIGWGEWHWDAWSEGLQGFTEEVSRRTFGIDFADGMEALRRILAYDLPQIVSPRDLTFL
-----V-------------------------EASQRS----FAA------------FLKMEDREQSRYPRP----AL-----AVAYAAPRNDLETRIATI
WSDVLGIDPIGIDDNFFDLGGNSLLGLDLFGRMRKALKLNFPAYVLYESPTVELQAAHITNL----------
>tr|A0A0C1RDM4|A0A0C1RDM4_9CYAN Uncharacterized protein OS=Tolypothrix bouteillei VB521301 GN=DA73_0203475 PE=4 SV=1
--------------------------------------------SNTLVFIDECGLGSQLVKLELEGQNVITVKVGSEFIKLRDDVYTLNPREENNYNAL
LNELRTQGKTPQTIVHLWNVTSEGEAEGPESIDKSQDLGFYSLLFLAQALGQQSEKLRIAVVSNNMQEVTGVEALCPEKATLLGPVKVIAQEYPNISCCS
IDIASAPQRQEEKLIDQLLHELQTQFSDRVIAYRGSHRWVQTFEPVQLDKPNEA-TPGFRKGGVYLITGGLGGIGLVLAEYLATTAQAKLILIGRSALPP
TEEWVSLKIRKVRK-LEELGAEVLAIAADVSNLQQMQEAIAKAKAR-FGQIHGVLHAAGVP-GGAIIGKTRDSVEKILAPKVKGTLVLDSIFKDTPDFFV
LTSSITSI-IGGFGQVDYTSANAFLDAFTHYKNSQGDNFTVCTNWDTWQEVGMAVNVSL---PDEMLKLAILPAEGVDAFSRILGTQLSQVICPRDLHLR
-----E-------------------------AWENT---------P-------KFLEPSETISSRPSHPRP----EL-----SNAYVAPRNELEQTIANI
WQQLLGIEQVGVYDNFFELGGHSLLATQLISRMRETFQVELPLNSLFEESSVAGLAER-IDK----------
>tr|A0A0K1JV17|A0A0K1JV17_9BURK Uncharacterized protein OS=Massilia sp. NR 4-1 GN=ACZ75_04085 PE=4 SV=1
--------------------------------------------DGWAIVGGADQQVAALSTLADLGQAAECASSAAGLGALA-------PGI-------
-----------RTVIALDGIADHM----------PSTELYYRALALLHGLSRR--PTTVLFVTRWTFAVPREREIEPERAAVIGLAIAAAQEYPQLSCRL
IDLDAAALSFGGAHAAALLAEA-LPQAAPWIAYRGAQRWVLTFEPAPLAPVQP---LAPAFEGCYLITGGLGKIGLLIAEFLARRGAATVVLTGRRAMPP
RTQWSDPRLGRLRM-IEAMGTKVVLCSGDGGVAADVARLVAEARAQ-GGKIHGVFHAAGLTA-AGFADIGRDVSEAHFAAKPRAARLLAEALRDDPGFIC
LMSSISAVLG-GIGFGPYAAANAMLDALAAQ----GATRWLSVNWDGWSFDTQ---------GAASSEALICADDGIDVLERVLAAPIRQLVSVAPLGPR
-----L-------------------------QRWLQP----PAAVA-----A-----P--AAAPSASHERP----EM-----SAGFVAPTPGRQTLVADL
WRDLMGISPIGADDNFFELGGHSLLAIQVVSRLREALQRDLPVRILFDHPTVAALAAALDAL----------
>tr|H8MFK9|H8MFK9_CORCM Malonyl CoA-acyl carrier protein transacylase OS=Corallococcus coralloides (strain ATCC 25202 / DSM 2259 / NBRC 100086 / M2) GN
--------------------------------------------QRWLVLEADTPVASRVSRLRQAGADVVSLVAGQGASDPVTKRFAVDPSSPDALGEH
LERLRGEDWSPAHVAYLWPLVKDS-----RDLESGLATSFHGLLALAKAVGPG--PVTLDVVTTGAQDVTGEEPLLPWQAAAVGASRVLPQEYPGLTVRA
VDVTWPAPE-SGPWMERLVTELAA-GKDPVVALRGPYRHVEAFETIDVPAPTE--QG-LKDGGVYVIVGGLGRVGLALAEQLTQAVKPKLVLLSRRTLPA
PGEWTSKAIDRMRA-LERSGAQVLALRADAGVPGQLDKALQVAEAK-FGRIDGVFYAAGDGG-ASVAEATPEATTPLLSGRFGGLTRLAEALASRQDFVV
VQSSLTVVLG-GMAVSAVAAAHAGMDAVAARR--LGGTRWYTVDWDVWGVGE----------GF-RPDAVIPPTEGFRLLRALLTQPGGRFASLGSLEAR
-----R-------------------------QVARDG----AST-----------SRA--GGSGSGKHPRP----PL-----ANAFVAPRDETEEKVAAL
WQDLLGVESVGITDNFFELGGHSLLGVQLLSRIREAFQVELSMRALFESPTVEVMTVAIVEA----------
>tr|H8N207|H8N207_CORCM Malonyl CoA-acyl carrier protein transacylase OS=Corallococcus coralloides (strain ATCC 25202 / DSM 2259 / NBRC 100086 / M2) GN
--------------------------------------------GGWLLFVDGPGT--AVARLRRSGCSVVEVVPGSDFLPLAADRFAMDGTRPEHHAWL
LEALGDARPERVAFLDGWALAGHAPGS--AHVEAAIARSFYPPLYLARAMEAR--VTSLTVVTAGAHDVTGEEPLDPAQALALGPCRVLPQEGPGWRCRA
VDVTVPPKESARMWLDTLVAELESDPRDAVVALRGRHRWVEDFAPVSLPDV-S--TGLLREGGVYLITGGLGRMGLALASRLATEVRARLVLVGRTGLPP
REAWTSRKLRVLED-LERQGAEVLVVSADVTSDEDCQRMVALARER-FGALHGVIHAAGVVG-PLVSEVVPSRCGLLFEAKVHGLLALTRALKAEPDFVM
LQSSLSTVLG-GLGFAAYASANHFLDAFAAER--HGETPWLSVDWDGWTE------------E--AGRLGLTLEEGARAFQRILGLGGGRLVSTGELSAR
-----R-------------------------ARGTVP----SEAAAA----V-A-GAP--GSRPASAHARP----AL-----GTPYVAPEDAIQQQIAEL
WQELLGVDRVGIHDNFFELGGHSLLGMQVVSRLRELFSVEVSIRGLFETPTVLGVVNAILEA----------
>tr|D8PF63|D8PF63_9BACT Putative Polyketide synthase OS=Nitrospira defluvii GN=NIDE2152 PE=4 SV=1
--------------------------------------------DHWLVFVGDRETESVLRQLESRVASVTAVFPGAGFECHADGSYRVRPDSREDHASL
LEELTARGQVPHCLLHAWGLESTGTDTADTRMRTAQERGFLHLVILAQTFGGR---CSILVLARGLHDVTGDELLRPEWTTMLGACLVIPQEYAVLSCRL
LDLDRRAFQ-VNVWGERLVTEAGLSRGAPVVAYRGQHRWVRTFEPLCLDAKGG--DLPFRQGGVCLITGGLGGVGLHVAEHLIRTVRARLVLVGRSHPT-
-----AEQREFVAA-LERLGNEVLVCRADVADRAQMQRVIDEAHQR-FGGIHAVVHSAGVAG-G---LKTPNAVWEEFRAKVQGAAVIDALFRDEPELLL
FCSSLTAVAG-GVGQSAYCAANAFLDALAHAR--REARRVISVNFDRWRHIGMARQAEA---TLDSDVDGMDAVEGLEVLRRILAGPLAQVQSIRDLPAV
-----M-------------------------ASVSHL----GLLDRG---GL-S-QKAK-----------------S-----TDELIVEKEGLEAQLAAL
WRQVLGLEHVGLEGDFFQLGGESLSALQILNRIQELHHVELSLREFLSAPTIHGLAGQIRTA----------
>tr|I4MQ87|I4MQ87_9BURK 6-deoxyerythronolide-B synthase OS=Hydrogenophaga sp. PBC GN=Q5W_1764 PE=4 SV=1
--------------------------------------------GTWLIAGGADALAEALARVREAGASALRIKEAGEAESAV----------AQA----
----RAGGQPVVGAFALWGLGAGAATP----------KQRDWLHHAPVALAAASEPVRVIVATAGAHSVLGEPVAQSAAALAVGPVLALPLEMPGLRGRQ
IDLEAGV---DDLAAQHLCDEAVARDEEDMVARRQGQRWLRRHEHTALPAANA--DLPLSEGAVVLMTGGLGGMGLAIAQRLAERRRARLLLTARTALPP
RAEWHSLTITALRA-IEAAGGEVELAQADAADASAMAAAVQAARAR-WGRIDAVIHAAGVAGGS---LKTPESIEAVLAPKLDGLRVLRELLADTPELVV
LMSSINAVLG-APGVADYASANAVLDAFAESV-PPAWRRVVAFDWGAWREVGMAAKLEV---PAAYLAKAIGTQDGLDAFERVLAS-LRRVVVPYDLPKA
-----L-------------------------SLTRAA----ALKPPA---EA-P-RTE--SAPREATPAKD----AA-----PAGARLPQGEVQTRLAAI
WVELLGVDSVAAHDDFFHLGGHSLLATRVLARIRESMGVQLALRDMFDASTLQALAQRVQEG----------
>tr|E3FPD0|E3FPD0_STIAD Polyketide synthase subunit OS=Stigmatella aurantiaca (strain DW4/3-1) GN=STAUR_4158 PE=4 SV=1
--------------------------------------------SGWLVFLDPTGIGQRLVKLEAGGAEVTCVSLGTEFSRKGEKRFELAPGQQAQFRML
GEELQRLGRLPGHVVHLWGLTPETAGQEETVVRSQQELGFYSVLFLSQALAEH--PLQLDVIAHGTQDVTGEEPLSPGKAMVLGLCTVIPQEHPAMRCRS
IDVEPPEAGRLS---ARLFQEVLSEVHGHGVAYRGHRRWVEFFEPVRLGAPGE--DGLLRERGVYLITGGLGRIGLVLAEHLGAAVQARLVLVGRSFFPE
RGAWTSQKIRRLLA-LEQKGAEVLVARADISQPAEVEALLAKVQAR-FGGLNGVVHGAATTG-EPIREADKDACENQFRSKIHGLRVLRDALRGKVDFVL
LQSSLASILG-GFGFCAYSAANRFLDALAALR--GGSTRWISVNWDGWEFGG----------VGQSGALPMSASEGVEAFQRILSGDASNWVSAEALESR
-----L-------------------------AVWIE-----QKGSAK----A-A-QDK--PVEVASLHQRP----DL-----PTEYVAPRDDLEAEIAGI
WAELLGVQQVGIHDSFFLLGGHSLLGMQLLSRIREQLKGDIPLRSLFETPTVAGLALLVVQQ----------
>tr|I1D2G6|I1D2G6_9PSEU Polyketide synthase family protein OS=Saccharomonospora glauca K62 GN=SacglDRAFT_02241 PE=4 SV=1
--------------------------------------------TWLVVGATGSV-VERLV---HSAARMIRVSWDASFA--GGDRFTVSPHEVSDWTKV
LRTVSESGSVPARVVFGAD--------------ERDFTALYGLMLLMRAWRDCVDDVEVGVVSVSGLPVAGESEVFPERGMLAALCRVIDQEMPQARCRF
VDITPATSP---RLLTRLVTELR---TDDCVAYRGDTRWVRGFVPARL--DR----TRLRDGGCYLISGGLGRIGAVIGDLLAT--RKAIGVIRRSVVPD
RADWPVAEITTIRR-LEAAGATVAAASADVSDPERFAAAVARLENE-LGPFDGVFHVAGVVTD-PLAEATPERARPHLAAKADGVRVLADVFAGREDFVL
LCSSIASVLG--IGFPAYAAANLYTELFAAARSAEGGTPWTALAWEGWTVDDRAAPE-----TAYLIDE----NDAREVLERVLSGDA-QLNS-------
TGDARF-------------------------DQWSG---------TR----E-----T-SAPRSSAAHARP----EL-----QTTYVAPRNDTERRLAEI
WQDLLGIDRVGVHDNFFELGGHSLLGTRVIARVLRELRVQVPLHT-LTEPTVAGLASAVAEL----------
>tr|A0A0M9E7J1|A0A0M9E7J1_9DELT Polyketide synthase subunit OS=Candidatus Magnetomorum sp. HK-1 GN=MHK_004304 PE=4 SV=1
----------------------------------------------WIIFLDHEGIGKQII-LSDKNVNIITVEKGKKYQ--GSNAYTLNASNHNEYEML
IKSLDGITI--HQIVHLFQVSSD-----TNDYSQLMNNGFYSLLFLGQALGKHSQ-IIVTTISNNMKDITGNDKIYPEKSAILGPLLVLQQEYQNINCRN
IDIVLPGKEQEKRLIEQITSELI---GNLQIAFRGNYCWYQTYEKITLEKPET---QLYRKNGVYLITGGLGSAGFEISKYLAKKVNAKLILVCRTKIPS
KENWISERIRKIQT-IEMAGAEVFIGAANVKDLSEMKAIIEEAESQ-LGGINGVIHAAGLVDA-YIADTDVSECKKHFDAKIHGTKILDQLFQEHDDFCV
LFSSLASILG--LGFAAYSAANIFLDHFVEAKNQNIRKNWKTINWGDLNFDKPEESTQNFDTVINLEALIINPDEMINTLERILLSNVNEWVTPGSLYAR
-----I-------------------------AQWVKY----DSMDHED-TST---S--------NEFHSRP----DL-----FNPYTEPTNETEKKLSNI
WENLLGISPIGINDNFFELGGNSLLLTQLASKVRNTFQLDIPLHH-FEKTHIKPLAKQIDTI----------
>tr|A0A080MEG8|A0A080MEG8_9PROT Beta-ketoacyl-acyl-carrier-protein synthase I OS=Candidatus Accumulibacter sp. SK-02 GN=ppsE PE=4 SV=1
--------------------------------------------GPWLLFTTGEGFSEHLAQLQADGQAVIRVLPGTQAGWSGERRYTLDPARRADYDSL
LAALSSAGQLPKTVLHAWNLAPAAGAPDRESFARAQDLGFNSLLYLAQALGERTEALRIGVLGTGIQALTPGEQPIPERAGVLAACIVIAQEYASVDSRC
YDLLPPAVGAEQALGRQILREIGSDAPDAIVAYRDGVRWVQHYQPRHLEPVSGP-PARLRPQGVYLISGGLGAIGYALAEELVRSVQARLILTGRSALPP
AAEWDNQRIARVRA-LERLGAEVLVVSADVADDDAMTRALAQARSR-FGHIDGVIHGAGIV-EQAVQDTRPEHCAEHFRPKVDGLLVLHRLLRDDPDFYI
LLSSISAVLG-GLGYAAYAAANAYLDAYAAHASRQSGPAWLSIGWDAWLSAASADRHGMG--AV-VNTLAMSTAEGVDAFRRILAADGAQVVSTSDLPTR
-----V-------------------------EQWVKR----KPRAA-----A-----------TPMADATP--------------SITYATAMQTAIARI
WENVLGVSQIAAQDNFFDLGGDSLLLMDVIARLKAGYGIVLNPREIMFQ-TLAQLAAQCEAR----------
>tr|W4LZV7|W4LZV7_9DELT Uncharacterized protein OS=Candidatus Entotheonella sp. TSY1 GN=ETSY1_00050 PE=4 SV=1
--------------------------------------------LCWLVFVDDCGLGPQLAQLQQGGQTVITVTAGEAFHQQDTLTYTLNPSREADYQDL
FNALRTAETLPDRIVHLWGVTPASPGP--ATTDTIQNHGFYSLLSIARGLGEHTEPLHISVISNQLQAITGDESLLAEKATLLGPCRVIPQEYPHITCRS
VDIVLPQQTAAHGLVEQLMTELISETPEVIVAYRGQHRWVQIFESVRFNSERA---TALRPGGVYLITAGLSDTGLTLAHHLAQTVQAKLILLDATPFPD
PSDWTSHKIDQLRT-MADLGAELLVMQADVTELAEMQSALKQAEQR-FGPLHGVFHLTSTR-SGLIQLKTAEQAQQVLAPSVIGTRVLNALLRDQRDFLA
LFGSVVSVTG-GLGQVDECAANAFLDAYTYSHDLPQPCHVVTIDWPGWQWDDYFEQSMASFPQVQRERYGITPEELGQATAQLLASDLSHVVSTQNLDLV
-----I-------------------------ELQTGQ----TTTNL-----V--------AQLDTAGSAQP----RS-----EGTYVAPANEIEAKIAKV
WAEEFGIEQVGRDDNFFDLGGHSLMAIQVISRTREVLEIDLPLSSLYSHPTVAALAELHMTT----------
>tr|S4Y1D7|S4Y1D7_SORCE Uncharacterized protein OS=Sorangium cellulosum So0157-2 GN=SCE1572_31230 PE=4 SV=1
--------------------------------------------STWLVFIGDEGLGAALVGLARRGHEVVAVVAGERFEQTGPQRYTIDPAAKGDVASL
FARLEVEGRMPDRIVHAFCTSPADGARGGAALEIERRLGFDSLLLLAQVIAAQPKPLMLGVITTRAHSVIGTEVIEPLRALVLGPCRVIPQEMPHVSCRN
IDVDLPGEG-RAEIAARLIADLERESPDAVVAYRGGRRWVESIELTDVGRRSA---PRLRQRGAYLITGGLGGIGLVAAELLAREAHARLILVGRTGLPA
RQGWTSRKIVRIRA-LEEAGAEVTIAAADVSDFDAMRSVIEEARTR-FGRIDGVIHSAGIA-GGVIQLRMPTAAWRVMAPKVGGTLVLDALLRDERDFLL
ICSSLASLVG-GATQIDYCAANAFLDAYAQSREGEEGCRVISVQWDTWSDVGMAVDFELP--ADETLKRGISSSEGAEVLGRILSAGSGPLICTSDLPAY
-----K-------------------------QSVTT-----------------R-RSQHEAPAARPLHSRP----TT-----TGAYVAPETETERRIAVI
WQDLLGLEQVGANDDFLQLGGHSLLATQVLSRVLLTLKVGISLPQFFDVPTVAGLSRLVDAA----------
>tr|S0FVE6|S0FVE6_9FIRM Beta-ketoacyl synthase OS=[Clostridium] termitidis CT1112 GN=CTER_1459 PE=4 SV=1
--------------------------------------------GTWLIFEDETGLSENIVTLKEEGVQLVTVSKGHQYCKMNQSAYTINPKTKEHYVSL
VKDVFK-GNKPGSILHLWNVTEEELGCTLEFSEECLSHGFHSLLCLAQALGETDHNIKMAVVSNNMQVISDEKVCYPAKAVITGPCKVIPMEYSNIFCQS
IDLVLKGIGEKSRFAKAILAEISAEEPQTTIALRGNHRWLPTIECTTLESINER--SWVKEGGTYLITGGLGGIGLAAALRMAREAKVNLILTRRSAFPE
KDQWAGDIIKQVKA-LEALGSEVMAIQADTSDLEQMSEVIRQAKSR-FGSIHGVIHAAGIS-NGLIQEKQAEAADKVFAPKVAGTLIIDELFKDEDDFMA
LFSSSSSILG-EAGFIDYCGANAVLDAYAHYRSQMSNTFTVSVNWDEWDEVGMAVKTGSR--S---KRQKITVHEGLTLLERIIASKLAQVVVPDDFMGR
-----L-------------------------QEIEEF----RMSSV---------RGNSGAKVTNQSNNRP----NL-----DVPYTAPQNELEEVIAGI
WQEQLGVYPVGIHDDFFELGGHSLLATSLITILRKKFHRNVNLQSFFEQSTVAQLAKILGDS----------
>tr|G3J047|G3J047_9GAMM 6-deoxyerythronolide-B synthase OS=Methylobacter tundripaludum SV96 GN=Mettu_3715 PE=4 SV=1
--------------------------------------------PEWLVFADELGLADALAEQTQNGRQVFKVNPGSGFAQPHERAYTVNPVQPADFDAL
LEALQQQNALPQQIVYLWGFSQSNPAA-------DLNRHCDSLLALIQALGRLRLPIELTVVGNNMQAIGADHPIDPAKAALLGLLRTLPWEYPNLSCRA
IDIPLPATEQLHSLASRLARELSIPAQDPLVILRTGYRWLPSLEAVRPDSPRET-ACLLRNGGVYVITGGLDGIGFLFARQVAAMVQAKLVLTTAGSLES
-----AANAQQLQE-LEALGSEVLPIQLVDYDTPSLNAVLNQAEHR-FGRIDGIIHAADMS-PRLMQDIHKTEQDAYWQAQQLTLNALKQSLEHRNEFCL
LMSSLAAEVG-GIGQAAHAAACVYTEAFARQHNQTGAYPWIVVHWDVWQEEGDRTDINSA--L---AEIA-TPEEGGNAFQRLMALGSTCIIATSDPRFR
-----R-------------------------KAFSRL----QE------------DQPGATPAAGRRHERP----DL-----SNPYEPPRNEDEAAMAEL
WQEFLGIDPIGIHDNFFDLGGHSLLATQLVTRLQQSFKVGVELVLFFTAPTIAELSEALLQK----------
>tr|B2IXJ8|B2IXJ8_NOSP7 Beta-ketoacyl synthase OS=Nostoc punctiforme (strain ATCC 29133 / PCC 73102) GN=Npun_R3024 PE=4 SV=1
--------------------------------------------GCTLVFSDDCGLGLGIVQLELEGETVITLKVGSEFHQISERLYSLNPKNHQDYDTL
LQELHRQGLQPQKIIHLWSVTENYTPEEIAEFDKAQETGFYSLLFLAQTLAKHIDELQITVVSNNVQQVTGVDIVCPAKATILGPVKVIPQEYPNITCRN
IDIIIPKSS--DKLVEQIVAELTCDNLDKVIAYRGYHRLVQTFEPVQWDESVVG-TPRLREKGVYLITGGLGKISLLLAEHLAKTVQGNLILIGRSPFPA
KDSWISQKIQKLIE-IESFGGKVLIINADVSNQQQMQAAIDLAKEK-YGRVNGVIHAVAIA--DAIEQTSYQECLQQFQPKIHGLLVLEKIFQNQKDFCL
LLSSLSSILG-GLGFVAYSAANNFLDIFAHKYNPNNSIPWISINWDAWQFDSEPKIT-----GN-LAELALNPQEGIKIFQYIFSQPVNQWVSTGNLQAR
-----I-------------------------DQWIQL----KILGN-----R-----KDLSASSITHHARP----NL-----RNAYIAPSNEIEKCLVNI
WQDLLGIEPIGIEDNFFELGGNSLTAIQIISRLREIYLIDLPVNDFFETPKIISLTETIFQA----------
>tr|A0A0C2LQD8|A0A0C2LQD8_9CYAN Uncharacterized protein OS=Scytonema tolypothrichoides VB-61278 GN=SD80_00755 PE=4 SV=1
--------------------------------------------SNTLVFIDECGLGSQLVKLELEGHNVITVKVGSEFTKLSECVYTLNPGQGNDYNTL
LNELRTLGKTPQTIVHLWNVTPNSEAEGLESIDKAQDLGFNTLLFIAQALGKQNDKLHIAVVSNNMQELTGVEVLCPEKATLLGPVKVIAQEYPNISCCS
IDVVIPPKGHEEELTLQLLAELTTQSSDKVIAYRGLHRWVQTFEPVQLDKSNEA-TPQLRKEGVYLITGGLGGIGLVLAEYLAKTAQAKLILIGRSALPV
KEEWVSLKIRKVEE-LEQLGAEVLAIAADVSNQQQMQEAIAKAKDR-FGQINGVIHAAGVP-GGVIQAKTTDRVEKILAPKVKGTLVLDSIFKDTPDFFV
LTSSITAI-IAGVGQVDYASANAFLDAFTHYKNSKRGTFTVCTNWDTWQEVGMAVNAAL---PAEMLKGAIAPDEGVDAFSRILESKLSQVICPRDLQIR
-----E-------------------------DWENT---------P-------KLSEPLETISSRPTHPRP----EL-----SNAYVAPGNELEQTIANI
WQQLLGIEQVGIHDNFFELGGHSLLATQLISRMRETFQVELPLNSLFEESSVAGLAER-IEK----------
>tr|K9X6G3|K9X6G3_9NOST Beta-ketoacyl synthase family protein,acyltransferase family protein,phosphopantetheine-containing protein OS=Cylindrospermum s
----------------------------------------------WLVFVDACGLGKELV-LEQQKHDLITVFVGKQFA--SDNAYIINPQRQDDYEAL
IQQLRQLDRIPQAIAHFWNVTSYDQS-ADRDFENSQYLGFYSLLFLTQALDKQTYPLQIITVTNNLHEVTGEESLNPEKATLLGPCKVIGQEYPNIFCRS
VDVVIPKST-NEKLIDYLIEEFT---DDLIVAYRGHHRWVQTWEPVQLGAVIE---TRFRNRGVYLITGGLGNIGFTFAKYLAKAFKAKLILLGRSDLPI
KENFVSRQIQKVKA-LEELGAEVLVISADVANFEQMQVAIAQADEY-FGKINGVIHAAGIVGDNLIQEIGKAECEMHFQSKVHGLFVLQKLLHSREDFCL
LLSSISSILG--LGFVAYSAANLYMDAFTYQQNRTKTVPWISLNWEGSPVDKEEQQNTNN--QSTLAELFITTTESVEVFKRVFS-ILSQIISLGELQAR
-----I-------------------------NQWLKL----ESIRDVE-PSK---QDTERQKDSPQLRPRA----NL-----QTAYVPPRTPVEFVVANL
WQQLLNIERVGIYDNYFELGGHSLVAVRLMAQIQRKFGQNIPLAA-FQAPTVEKLASVLQET----------
>tr|Q6E7J4|Q6E7J4_9CYAN JamP OS=Lyngbya majuscula PE=4 SV=1
--------------------------------------------TTHLVFVDEFGFGDKIVKIERDGQNVITVKVGTEFKKLSDRLYNLNPEQENDYHAL
CQELRERNENPKTILHLWSVAPNSKDKEIEWVEKSQNLGFYSLLFLTKALGRQSGELLLGVVTNNMQKIGSEALLNPEQATVTGPILTIGQEYPNIICRS
IDVVVPESGEEEILIEQIGSELAIEQSEKMVAYRMGDRWVQTFEPVRLEEGDKT-NPRLKPGGVYLITGGLGGIGLILAEHLAKTVQAKLILIGRSKIPP
AEEWISQKIHKIRK-LEALGSEVLNICADVANLQQMQDAISKALKR-FGQLNGVIHAAGIV-DKTIAKAAKTECEQQFKPKVKGTLVLAKTLEKLEDFCI
LMSSLSSVLG-GLGFVAYSSANSFMDAFVHQHNQTSVVPWIGVNWDGWQVIEAKKTS-----KSSLVELAILPEEGINVFQRILSTNLHRIVSTANLQDR
-----I-------------------------NQWVKL----KSLQQ-----SDKKKSDKSKTEPSSFHSRP----KL-----ATSYIAPRNQTEQTIANI
LQQILGIEQIGIQDDFFDLGGDSLIAVQVIYKLRETLQIDLPLEAILNTGTIAQLSESIQAT----------
>tr|A0A0M0SRD7|A0A0M0SRD7_9CYAN Uncharacterized protein OS=Hapalosiphon sp. MRB220 GN=AMR41_08275 PE=4 SV=1
--------------------------------------------LCWLVFIDACGLGSQLVQLEQNSQDVTTVMLGEQFTRHGESVYTINPRKRDDYDAL
LKELHALNKAPKTIVHLWSVTPNADTSEIEFFEKSQYLGFYSLLFLAQALGEQTDPLQIVVVSNNMQEVTGVEALCPEKATVLGPCRVIPQEYPHITCKN
IDIVISESEDERGLLGCILSELAAPPSNLVVAYRETHRWVQTFEPLKLEESVKE-TLQLRSHGVYLITGGLGGIGLVLAEYLAKTVQARLVLIGRSAFPR
KDQWVSRKIRKLQV-IENLGAEVLIKSADVANLEQMLSAITQAYEC-FGEIHGVIHAAGIV-TETIQETSQVECSEQFQAKVRGLFVLKKVLQGRADFCL
LTSSLSSVLG-GLGFVAYSAANLFMDAFAYI-CKQTGTPWISTNWDGWKLQEEKKQN-----IATLAKLVITPTEGVEVFQRLLSISPVQVVSTGDLQAR
-----V-------------------------DQWIK---------RE----SLGN-TKSPKVDSSSLHLRP----NL-----HNAYVAPKDDVEQTLANI
WQEFLGIRQVGVHDEFFELGGHSLLAVQLMARIEQQFKKNLPLATLFQNSTIERLATILRQP----------
>tr|A0A068J707|A0A068J707_9BACT Putative NRPS/PKS hybrid synthase module B6B OS=uncultured bacterium PE=4 SV=1
--------------------------------------------TDWLVIGDRTRVSDRLVQLKLRGDRIVSVGFGESFERVSADSFTISPEDT-DCARL
VDALIEESRQIDKVVYLWTSEVDGSF-----APRETDLGFYTPMFLAKALNELRPALDLYFVTADAQQVTGDEEIRPARALVAGVSRVCGQEMPHIRARC
IDLEDFNGQAVERNIDCLLAEMSLPEDSREIAYRGRYRWVKTTEPMPLAGQQAG-TGHLKHKGVYLITGGLGGIGRALAGFLAENYQARLVLVGRTQLPE
ASARVSEKLKFIGE-LEASGAQVLTVGCDVADFEAMKVAVETATGT-FGGIDGVIHAAGLP-GGLIQLKDRQSAEKILAPKVQGALVLDALFADGSDFML
YCSSLAAVLG-GVGQVDYTAANIFLDALALQ-RQRRGLYTVSVNWDIWGEAGMAAAAEVPAGYEKALDAGIRSAEGVEVFTRVLQQNYPLIVSTRAVLQA
-----A-------------------------AGSARR----KPEIGNYGIEQT--LGDESEPGQGAEDAGE----AL-----PETYIAPRDELESLLCNI
WQEMFGIRQIGIEDDFFELGGHSLLAVQILSRIYESTDVKISLNDFFDAVTIAKLAEKISQQ----------
>tr|A0A0N7ATF0|A0A0N7ATF0_9DELT Polyketide synthase OS=Myxococcus virescens GN=benB PE=4 SV=1
----------------------------------------------VLVFLPVSRFGQSVV-LRRRGMQPITVEAGDGFA--GDSAFGLSPTEEDHYEQL
LEALG---GPPGQVLHIASTGRTGSR--QERAEATWRHGFQPLVLLARALGRRST-VRLVVATDSQYAVSGTERLLPESALLAGPCRVIPLEYFNLRCHQ
VDVSLGGLEQWAQHAACLVDELS---DEPVVAYRGGQRFVQHFERLTLTAP-----PLFRPEGVYLVTGGLGGLGLAIAAEIAKTPSTRLVLLGRSGLPP
RETWLQERIRAVRE-LEASGAAVHVVEVDVSDGPGMRQALQGIRER-FGQVHGVVHAAGVPG--MIQRKDLEEARRVLAPKLDGLIHLEPLWEEGADFVC
LFSSSIALSG--IGEVDYCAANAYLDAFARELS-RRGIRALSINWGPWKWDAWQGHSVALPEAALRDTYGLTMEEGQRAWRELLS--TDQAVAPAGLKMA
-----I-------------------------DGIGKD----F-LQE--------------SQGTQSRHPRP----PL-----LVAFVAPRDALEERIAAA
WQDALGIESVGVNDNFFDLGGQSLGALQVISRINSEMKTTLPGAT-FEAPTVAGLARLLRQE----------
>tr|A0A0K1EKL5|A0A0K1EKL5_CHOCO Polyketide synthase OS=Chondromyces crocatus GN=CMC5_053580 PE=4 SV=1
--------------------------------------------GTWLILSDEGGLGDALAHLCAAGQQVVTVLAGQAFSGLDTERCYLRPASFGDYDRL
VAQLCAAGRRPARILHLWNVDSDRQEGGAPTFEQAQHVGFHSLLFLMQALREHDDPIQLWFLARDLHSIERHDRPRPEKVTALGALRVIPQEYPCITCRS
IELPPAEGRTGRRLLDHVLAEIAEISSDVDVAYRGDQRWVQGFAPAPLAVPRGS-CPVLREGGVYLVTGGLTGLGAVTSVYLARTARAKVAIVDSLSLPP
RATWMREAITTIQA-LEGLGVEPLVVCADVADADALAAVMVQVEAR-FGALHGVVHAAGAR-EAALSELDVGEVARQLGPRVQGLLALEEALGARSELLV
VQSSLSSVLG-GLGLAAHTAASRCMDALAHVQASHRAATTLVINWDALRPESDRSSGEVGRDVADASAGAISAADAALALHRILWSRGAQVVSPTHLPTR
-----L-------------------------SRWVER----SEP------------VVASPGGRASAHARP----HL-----ATPYVEPSSETEQLIARM
WQELLGIDQVGVQDSFFQLGGHSLLGTQLVTRLRQTFHVELSLRAIFEDPTVAGLALAIEAL----------
>tr|V6MC03|V6MC03_9BACL Polyketide synthase OS=Brevibacillus panacihumi W25 GN=T458_00155 PE=4 SV=1
----------------------------------------------WLFFANESFVSRHVHVQEDSEAEVYTIFAGTDYK--GPYEFTIEPDNPTHYEML
VKALHGSSPFPSRIVHAWHVDHDEESNWPHAFWQQQRLGFRSLLSLTQAMSRQDQNCMISVITSGLSDVTGDEILVPEKSTLLALLKVIPQEYRNMTCRH
IDIPVALANGTERLLAQLTEEIL---VDPTVALRGARRYRQTYEAVSLPKSDT---AILRQGGVYLITGGLGRLGMLFADYLAQQVQAKLVLTGRTILSA
LENELR---AIIEK-WQSIGGEVLMLQADVASLEQMRAAVAQAIHR-FGRIDGVIHTAGIMGA-DILDTDEEMIQKNFLPKVQGFYVLQDALKDVPDFTL
YLSSLSATLG--LGASAYAAAHTFLDYAARNSSHAKSSPVISVDWDGAATDTET----------------------LDAIDRIFAAKEIPLVSTRRLSDM
-----V-------------------------KKWLTS----APDPLHS--EK---Q------STGSSYARP----HL-----KNAYVAPQTELEQLIAAI
WSPLLGIEQIGVHDRFFDLGGDSLIGTQLISRLRATFEIDLTLRM-FEIPTVAEQAALIEEI----------
>tr|U5QK65|U5QK65_9CYAN Beta-ketoacyl synthase OS=Gloeobacter kilaueensis JS1 GN=ppsE PE=4 SV=1
--------------------------------------------GDWLVVAAG-TSGAAIVALEQRGQTALLLPNAPDLARQRT----------------
------------GILYLASDTKD-------ELESAWQQNCAPLLPLVRGCVQIDVPPRLYLVTQGAQVIESQENPVLEHIPLWGLGRVIAQEHPELWGGL
IDLDPAFDPAATA----LVTQLFSPDDEDQIALRGDARYVARLVRQKVEGGE----LSVRADGTYLITGGLGALGLQVARYLVERGARHLVLVGRNPPSV
T------AQTVLDE-LTASGATVSPVQADVSIAGEVEQLLAEIRQE-HPPIVGILHAAGVL-DGVIDKLDWSRFERVLAAKAAGAWHLHRLTQGDPELFV
LFSSIASLLG-SPGQANYAAANAFLDGLAQH-RLSQALPALSINWGPWAEVGMAARLDAQRHPWQG--LETPPEQALAALAGLTGTGTA------SLAVM
-----P-------------------------VRWQAF----LAQFPA---GHL---PPLLVSAASSPAAGPVLTQQL-----EQALPGERRLLVAHLRDQ
AARVLGIDNLDIRQPLHSLGLDSLLALNLTRQLGAALGRSLSATLLFNYPTVEGLAAHLAEE----------
>tr|A0A0K1EF47|A0A0K1EF47_CHOCO Polyketide synthase OS=Chondromyces crocatus GN=CMC5_036380 PE=4 SV=1
--------------------------------------------RCCLLYADSHGLGARMERLRRDGYEVILVRPGESFAAEGATAFTVDPTSASDHASL
LGALRRAGRVPSMILFLWGVTTPTRAPDAARAEAAQVFGFHSLMALAQALGEVREEVRLGVVTSYMHKVTEGAALCPEKTTVLGPCRALSREYGNVSCIS
IDVDLPEPRQEGRLIDQILAEVSLERTESIIAYRNGERWIRTYEPARMDRPDGL-PSRIREGGVYLIIGGLGFLGSTFAEHLARVARARLILTGRTVLPP
RAMWLRRKIRTVLQ-LERLGVEVVCMSADVTRIDDMREVVGRAVDH-FGRIDGVIHAAGST-TGSIQGTSREEAEAVLAPKLVGAVVVDDALRGLRDFIL
LCASRQAVLG-GARLASQSAASTFLGAFAQRQAAVGGPLTIAVEWDPWQRSESSDDRTPGDGVESSAGHVLSREEVLDAWMRILTNPTPQVVAKREEVAR
-----Q-------------------------RQSASS---------------IAPSKEVDESIPRSVHPRP----DL-----GTAYVAPRDPLERAIAET
WEKLFGIERIGAHDNFFDLGGDSLLAVQVISRLRGVVNMDLPGHSLLNAPTVAALAELIAQS----------
>tr|A0A017T2M8|A0A017T2M8_9DELT Malonyl CoA-acyl carrier protein transacylase OS=Chondromyces apiculatus DSM 436 GN=CAP_6179 PE=4 SV=1
--------------------------------------------RCCLLYADSHGLGARVERLRRDGYEVITVRPGAGFAVDGASAFVVDPASASDHASV
FGALRAMNRVPSMILFLWGVAPPVRAPDASRLEAAQILGFHSLVALAQAVGASREEVRLGVVTSNMQKVTETAVLCPEKCTVLGPCRSIPREYPNVSTIC
IDVDLPEPRQEGRLIDQILAEVNLERTESVIAYRNGERWIRTIEPARMDRPEGL-PPRIREGGVYVILGGLGLLGSTLAEHFARVARAKLVLTSRTVLPP
RETWLRRRLRSILH-MEKLGGEVLLLKADVTQPEEMRAAIAEARQR-FGRIDGVIHAAGIT-TDTIQATTRESADAVLGPKLQGALVLDDALRGFRDFII
LCASREANLG-GARLATQSAASMFLDAFAQRPAAVDGPLTIAIDWDPWQFSEGPRVEEREEADSGAFAASLTREDALDALMRILTNPVPQVVARREEQAA
-----P-------------------------RQAPGS---------------IAPSKEVEDSIPRSVHPRP----DL-----GTAYVAPRDPLERAIAET
WEKLFGIDRIGVHDDFFALGGDSLLAVQVISRLRGVVNMDLPGHSLLNARTVAALAELIAQS----------
>tr|S4XYJ6|S4XYJ6_SORCE Uncharacterized protein OS=Sorangium cellulosum So0157-2 GN=SCE1572_29775 PE=4 SV=1
--------------------------------------------QCCVVFADSYGLGARMERLRRDGYKVITVRPGEGFAETGEGEFTVAPASRADHASL
FGALRAAGVSPSRIMFLWGVTKPARAPDAGRLAEAQRLGFASLVALAQGIGDARDEVRLGVVTSHMQKVTDAAVLCPEKATLLGPCEAIPRAYPNVSCIS
VDIDLPEPRQEARLIDQLLAEVTLEQTEPVIAYRNGERWVRIFEPARMDRAEGL-PPRLREGGVYLIAGGLGAVGSALAEHLAKVARAKLVLAGRTALPP
REAWLRRKIGAVLE-MERLGAEVLLVTADVTRLDDMQRAVAEGLQR-FGRIDGVIHAAGAR-AVPLQRMTREEGEALLAPKLDGALVLDESLRGLRDFVA
LCAARTAGAR-GAGLAGQCAATAFLGAFAQRRAAGDGPLTIAIEWDPWQRQDASRGKDPEPAADAAAEEGISRDEALDAWMRVLTSPTPHVVLKREAQAK
-----Q-------------------------RPSASS---------------IAPSRDVEEGIPRSVHPRP----DL-----GTAYVAPRDPLERAVAET
WEKLFGIERIGVHDDFFALGGDSLLAVQLISRLRSVVNMDLPGHSLLNAPTVAALADLIAQS----------
>tr|G9CIA1|G9CIA1_9NOSO NpnA OS=Nostoc sp. 152 GN=npnA PE=4 SV=1
-AGEFDNIIQQFGINLDNPNLLPNWFYRQIWRQKAPVTQISAINGNFLVFIDQLGVGEYLGEFQKHGQKWVGVEVGVDFRQLSSNRYEIAPNNPEHYQLL
LSALAANNFQIDNILHLWTYDARISESSLESLEQAQTLGVYSLLFLVKALAKFDRAIALTTVSSYTQFTSHSDEIAYEKSPLVGLLKVIDQEIPGLTSRH
LDLSVDEPAV---NAGQILQEISVLPCESEVAYRQGQRWIPRLEKVDFSPQS---KPAFKSGGMYLISGGLGGVGVEIAKYLLKHYKARLLLVGRTHLPE
KSDLHTQKIAVYEE-LEQLGGKIIYEAVDVCDLPRLQQIVEQAQSRWGCELDGVLHLAGTYQERSLLEENHQSWSTAIRAKVSGAWVLNQLLKDYPQAAM
ISFSSVSRCLGGATVGTYVAANQFLESFAHYQR-SQGLKSYCFSWSLWDAIGISQDQQRSKLAQTKGYCAISARQGLYSLLIGLHHNQAHLLIGLDGSNR
HIRGYVEDTY-ALEKLTA--YFTVSDNSSIEERLSQL---RVRDRFGTPSTCNFVQLQKMPLTTTGIIDRDKLIK--GDLREPSEQAQPTSDIERQVAQI
WQEVLGLEEVGIDDNFFELGGHSLLLVQAQSKLQESFQIPVSIVDMFKYPSISALAKYLSQG----------
>tr|A0A0F7EFE9|A0A0F7EFE9_BRELA Polyketide synthase OS=Brevibacillus laterosporus GN=EX87_01510 PE=4 SV=1
-AGEFDEIIKQIETQNEDPHTFPEWMYARKWEERPISVLSPLPQETYLIFRDTLGLGDQWSSLSQNGSTMIIVDQGESFKKRGEFHYEINQHEQKDYQLL
CEELKKESVTIHHVLHLWTYQEDLAEKELSYLKESQFLGSFSLIFLLQALHKVGMPKTLTFVSSNVFSLENPEHSAYEKATIPGIIKTMKHEFPNTIAKF
VDIDTN-HPPYHPLL-ALQAEQGLPDEESVVIYSKGKRFVPKLQQVNLQEANKKTL-PLVEKGFYVVTGGLGGVGKQIAQYLIQKFDANILLLGKTALPS
ATDKQSEALRELEKLTAR-ENQIIYKSTDLSDVTVLEEAI--NESMLGEKVDGIIHLAGVYYEKPLLEESIESLEHMYESKVAGTYLLGKLVEKYPEAIL
VTSSSSSGLSSGYGVGAYTSANMFVETFTDYVAQRDGV--QCFAWSLWNDIGLGQQFDMKDLLIRKGHQPISPQKGIFSFELGLMLEHNMLYIGLNKGVS
EIATLCSEAVE--KELVTTVYFSTTHNQFSLSEMYSTI----RLH---------------TIDEKGHSTKVIFRQ-VDQLHSDAEDVSNNRRMEEEIKQL
WSEILQVDQLQAFDSFFDLGGSSLKATQLLSSVQSRFGVAIPLKVFFENPTIKGLIHRM-------------
>tr|A0A0K2M6K0|A0A0K2M6K0_9NOST Uncharacterized protein OS=Anabaena sp. wa102 GN=AA650_10330 PE=4 SV=1
-IGEFKPILKRIDILLGNSHTIPNWFYRQIWQPKSP-LINKDYLNLILVFLDSWGLGDYISRILSQYNPYITVSSGENFLEINNSCYQISPKEAEHYQLL
FNSLANKNIVVGQIIHLWTYDEYTGDIELEALKLAQTPGIYSLLFLVQALAKVDHSVKLLFISNHIQSILSTDLIAYEKSPALGLIKTIPQELPWLDCRH
IDLTFGEVEKNGDY---ILQELQISSKEREVAYRNGQRFVTRLEKVDLSKEPKH-PIPFQQGGTYLLSGGLGGVGVEIAKYLLRNYQARLLLIGRTPLPE
KST---WDLHLQKKDLEQLGGEVIYEAVDICDLNNLQAIVEKAKNKWGKNLDGIIHLAGRFHEQFVLAETQENLSALLRAKMLGSWTLHQLIKDKKDSFF
INFSSINSFFGGSAVSAYAAANSFLDCFSHYQKYQSALQSYCFAWSMWDEIGMSAGYQMKNLTRAKGFYAMPSSQAISSMLAALHHNQRHLFIGLDGNRN
ISRWQVET--ESLQKLT--AYFTASPVEIDADFQVKD-------DFGTVCTCKLVQVSEIPLTENGAIDRDKLVRRFI-RQETGVLIAPRNEVEEKIAQI
WQQVLNIPSLGIDDNFFELGGNSLLATQVISRIRKAFGVETSLQNLFQAPTIAQLSQLIAV-----------
>tr|K6YQV2|K6YQV2_9ALTE Uncharacterized protein OS=Aliiglaciecola lipolytica E3 GN=GLIP_1058 PE=4 SV=1
-AGHFYQQIKTADMLLGN-HCIPAWLFQPSWQLTQP-VLIQSLAQKKVIFAHQNTISIELVNQLKTLGEPILVTGSDTLSLNGNDPLQIRSVQSEDYTAA
MAHIADNKTSIDYVLCLWSLQDEDDTST----WDENSPQLYSAIVACAGICSYDQQLQLMYVTQGAQSWQSSQV-TADNAGLPALIKTLKQELPDINYVH
IDLALNEPDAASK----IIIELQSKQAGKDIIWSNQQRFSAELNPCRLTSIETD-PLAPNQPAGFVLSGGLGGIGQQLIKTLLHSAHAKILIIGRSSLED
VKQ---QHVNLSKWL----TANLSYVTADVTNSEAVNLAVKTWLSEQQVTLHSIFHLAGGYHEATLQEESVQGFSDLAVAKLAGANSFANILTQFPAANL
INFSSTAGVFGGATIGAYAAASCALDGLSHNLR-QQGLRCFDINWSSWRSTGMSEGNTAIEALRARGILELDIEAALNSLRLILGQGAGQYIVGLDPNPI
IRRLMPN----CLNSLTP-TVFSSEGTAGSEKLDFVD-------NFAQSFETPLLQIDKIPLLSDGQVDEAALTLIAT--QGNTEVVPAKTETEKAVVEI
WKKILNLDTVSIQWNFFDVGGQSITATKLIAAIRTQFAVNWTLKDIFSAATCEQQAAAIEQ-----------
>tr|A0A0P9KI65|A0A0P9KI65_9PSED Peptide synthase (Fragment) OS=Pseudomonas coronafaciens pv. atropurpurea GN=ALO66_04628 PE=4 SV=1
-DGSLESYFPAIDTTLQHRTIASVWCEQLQCEQVSNSVATQVVARDLLLFEASQGKSQQLDPQSSAYNPGGLHLRGERFYEHHIDTLDISDLPGEERQAR
ALQLDDHQLLVHIIADGWSLNVLIDEFSQLAYWKQHSASRYSLRLSA--L--------SAAVRNTAQAWQSTSFMFYETQGLIRLPGLLAEELPWHSREK
FDLQLHSEDRNGRL---NLFDYADELFERDTIVRLAQHYVRLLTQVQLLSAPAHVALQANRLAHYLRDKGVGPDVVDRLAYMLEDSGVELLLTGDLPSCT
VAM---DMLHLDNWPLHLHGDNLAYVIYTSGQKAPISFDVSVWECFWPLITGSRLLLAR----------PGEHRDPHRIAQMVNEYTLHPLLQLFIDPLT
QQCSSLRRLFSGGEALPSELRNRVLEQLPNVQLNRYGPTETAINVTHWGGIGLARGYLNRPGLTAERFIADPLGQPGERLYRRWAADALEYLGRLDQQVK
LRGFRVEP--QEIEPQLI-GYYTGAGQDVHAERLALE-------LPDYMVPAQLVRLDSMPLSPSGKLDRRALPEPQW---QTREHVEAQTDLQKQIAAV
WRQVLGVLRVGLRDDFFELGGHSLLATQIISRVRQACDIDLPLRALFEASELGAFAEQVQT-----------
>tr|A0A0D6WVN2|A0A0D6WVN2_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. MBRL 601 GN=SF12_07640 PE=4 SV=1
---------------ARRHTDPAQWFYAPSWQQTAPAPPADAAAHSWLVFADETGVGGELADLLELGATVRTVRAGSEWSRKGEGVYVLDPGSPEHYTRL
AEALREEGSPPDRVLHCWSVGSDADGTDPQNVRALLDRGFHSLLHWAQATESGSVPQRWDVVSSEVCSVTGDEALCPPKAAVQGIVRVLPQEYPSLTCVH
LDLAGGQTAPA--AVDAILPALSLPAGERTLALRGRRWWAPTFVAAEQPRRD---SAPVRADGVYLITGGLGKIGMLMARALAERERVRLVLLGRTGPEA
TRD----LIRGVRAL-EELGSEVMVCAADVSDPVRMREVKEAVVQAYG-RVDGLLHCAGTTGAEAVADLGERESAWHFDPKLYGTYVLDEVLADQELDFA
LLCSSIASLLGGLGFAAYAAANAVLDAFAQRHHG-AGQPWSSVNWEAWRFTAAPRDEAIGSAVQALALDPDEGRRVTDALLAAV----------------
------------PQAQVVVS---TSDPVRRREQWVA---------------P---------AAEAAMPRQQHERPNLR-----NPYVAPDSETERQVAVI
WQELLGVQSVGVHDNFFELGGSSLLGLQVVHRLRQELSLPVPLTVVYEGPTVRALGGLVDD-----------
>tr|G6FNP7|G6FNP7_9CYAN Phosphopantetheine-binding protein (Fragment) OS=Fischerella sp. JSC-11 GN=FJSC11DRAFT_0494 PE=4 SV=1
---------------LETKQNIADWFYIPSWKRSLLPQS-CR-DEKWLLFIDECGLGCELANRLKQGKNVTTVKVGEKFTKLSEGIYTINPYNYEDYDTL
LTELIALNETPQNIAYLWSISSLDT----PKLGDF--LEFKSLLFLIQTLKQKTERLQIWVVSNQIQEVNGNETLDPEKATVLGLCKVIPQEYPNIICRN
IDFVLKDSR-DFNILDQLLSEFSALSSDTVVAYRHNYRWVQVFEPVHLSAVE---ETPLRKHGVYLFPGGLDSFGVVIAKYLAKTLQAKLIFIDDSTEDE
VSG----KISKLQAL-EELGAKVLVVRADPTNSEQMYH--SLSPENIG-QIHGVIYSTGITRENVIPEIGKTDLEQLLDAQLRKYVVLEQVLQNRKLDFC
IIFSSLSSILGGFGLGLYSGINQLTDSFTQRHNQTNSFPWISINWDKLQLNAIQEQKTGQTSGVELAITETESVEVFKRVFSIG----------------
------------EGTQVVVS---TIDLKARWE-HT---------------------------LDPGVCSSRYSRPNLS-----NSYIAPTNELEKQITEI
WQEVLGIAQVGIYDNFYELGGDSLIATQLVSRLRAKFPVELPLRELLLQAMIPIKQAEMIE-----------
>tr|A0A0A6RNC8|A0A0A6RNC8_9GAMM Uncharacterized protein (Fragment) OS=Candidatus Thiomargarita nelsonii GN=OT06_48620 PE=4 SV=1
---------------SDKKPDIADWFYLPSWKRSVLQTS-EVLVYTWLVFIDECGLGSQLVKRLEQAHDVITVKIGATFTQLGERHYSLNPAQREDYDAL
FS---ALDKTPENIVYFWPVQPLNC----PSYSEVENLCFYSPVFLAQALEQGMDEISISIISNNMQQVAGETVLYPEKATLLGPVKVIGQEYPNLTCRS
IDLVLPNAW-QEKLIDQLFLELSAKVYDLVIAYRDNHRWVQTFEPVQLKSPS---VRILRKNGVYLITGGLGGIGLVLAEHFAKTVQAKLILIGRSTDNA
ISH----KIKKLQTL-ETFGAKVLVVSADVANQPQMQEVFSLARTQFG-QINGIIHAAGVPCGGM---KTRTTTAPILATKVRGTKILADLSKDISLDFM
VLFSSLSSIRGDFGQVDYCAANAFMDAFTHQLQH----FSICINWDTWQEVGMAANADSHTENLQRGILPSEGIEVFERILANA----------------
------------L-PQVLVS---TRDFDFQFSTSD---------------------------SDN---NKSNQRPQLQ-----NAYIAPSNDIEQTLADI
WQKLLGIEPIGIHDDFFELGGHSLLATQVISRMRDAFGVVLPLPTFFEVATIAQ----LAE-----------
>tr|A0A0N0SDQ8|A0A0N0SDQ8_9ACTN Uncharacterized protein OS=Streptomyces sp. WM6372 GN=ADK52_07360 PE=4 SV=1
----------------MRRDDITQWFYAPSWQREALPAG-EQ-TRHWLVFADAVGVGEAVAGRLRAGAAVTVVEAAGAWADRGDGRYAVDAGNGSDYERL
IDTLRNPAGAPTRIVHSWNVTAPGE-------EGSLRHGFESLILLAQALRHASEPRRIWVLSNGLHSITGAEVLSPLKATLLGPCRVLPRELPGTACRS
VDLDYGAALTERELVR-LMAEAEPERGPETVAHRGGHRWSQHFVQQRLPRGD---RPVVRKGGVYLVTGGTGGLGLALAGHLAA-AGARIALTSRTGRSR
LSN----VVRELVRL-RDAGAELLVCQADVSDRAAMDEAVRQTVGRWG-GINGAFHMAGVPSGGL---KDLRAAAEVLLPKVRGTLVLEGALAGQELDFL
VLFGSNGANMGSAGQVDYCAANCFLDAFAQDRGRTR--RVIAIDWGPWREVGMAADAA-ADQMDQRAMSPSEGLRALDTILAGV----------------
------------SEPQVVVS---PAELSALFENAFS---------------L----------QDTEPRGAVHERPDIL-----TEFVAPRTDAERTICEV
WQELLGIEKVGIQDSFFDLGGNSLIAIQVVSTVNTRLGAKLALGDLYEGLTVSHLAAVAEK-----------
>tr|S9Q7I8|S9Q7I8_9DELT Uncharacterized protein OS=Cystobacter fuscus DSM 2262 GN=D187_007048 PE=4 SV=1
---------------MNAEQDMPGGFSLPSWRPTLPPSAAWD-ACWWLLLPGPEGIGARLKQRLEAGQRVILLTPGPRLAQLGENHWSLQPAEAADYDLL
LRLLLPQGLAPDRVLHLWSLLPPRNGELEAAFEPAQEGGFQSLLFLLQALRQA-RPLSLVVLTHRM-QALGEESPCPERATVLGAVRAASRESPHVTCRS
VDVNLPAPGSWQRLADWLLSECAAASSSEDVVYRGQQRHVRAFTPIELPTAA---QLSPRERGVYLVLGGFGTLGSSHAEALARHVRARLVLVSRSLGDP
LSR----RIRHVRAL-EALGAEVRVISADVGDRDQLQSALEETLAHFG-ALHGVVFCVGSMNASLLADLTPDDVRVLFQSRVRGLYALEEVLRGRPLDFC
LLASSLAAVHGRGASAAYAAAMNFMDAFALRQAQRSPVPWVSVDWDGWASDDADALHS-VAPLGSRPITAAEGAELFTGVLSLG----------------
------------DVARVAVT---PRAPSAPATAQPP---------------P---------SAEPPSAARKASRPDLD-----TAYVAPRDEVEESIAKV
WESMLGITGVGIYDNFFELGGDWRTGMTVMTQVREKTGVPLPPVSLQEGPTVELLAQRLRA-----------
>tr|R8MA24|R8MA24_BACCE Uncharacterized protein OS=Bacillus cereus HuB13-1 GN=IGG_03072 PE=4 SV=1
------------------RSNIAEWFYTPGWMEKEIVDVTKGSTKSWLLFLDNEHIGLALKEKLERDGRVITVGVGPSYKKISLNEFTICPTEQEDYYQL
FNELQKQECLPEEIVHLWNVDNKD------LGIETLDTGFYSLISLAKTISKFLYPININVMTNNMQKVVGDESIIAEKSTLLAPIKVFPQEYPNIRCRS
VDFMLSDNEE--ALISNLYFEIQTDIIDTVIAIRNNTRYIRIYEPIPDENELASKIPNIRSEGVYLITGGMGGVGLKLAEYLARTVKAKLILVSRTALP-
-DREEWDQLHEQIQKLESLGAKVMTAVADVADEEQMRNVIHQAE-ANFGHINGVIHAAGVLRVKSMEKISRIECEEQFLPKVHGVLVLDKLLSNYDLDFC
YLVSSLSPILGGLGFVAYSAANLYLDSFSDKVSNTSNNRWTSINWGDWQYTGAQNKIFN---AQSIEALEMTSEEGQKTFQCVLGLSGL-----------
---------------NQVIIS-----SGDLNKRFDQW--------------IN---LNSRKRIS-GLETQ--------TQTKTGDKFRNQDEVEEIIIGI
WKEFYSVDTVNVNENFFDLGATSLHIIQIHERLINRLEKQISIGVMFEYPSIRSLARYLSGD----------
>tr|A9AV11|A9AV11_HERA2 Beta-ketoacyl synthase OS=Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785) GN=Haur_3967 PE=4 SV=1
------------------RADIADWFYRPEWAPAALNAPTNDSKQRWLIFVDAMGIGAGVRQRLAEHGEAVTVTIGEGFKRLDTHHYELAPTRLADYLDL
IAAIQGQDPLPTHVLHLWSLTPLA------GIAAAQDYCFTSLLNLARAFEAQTDSIHMLVVSKGMQAVDPSDIPDADNATLLGACTVIGQENTSIIVRS
VDLDVDLDARHDGYAAGLIAEGQSGSHDLHVAYRDGQRFAERYVPLRLE---ALSQPILRPGGVYLMTGGLGGVGLILAEHLARTAQAKLVLVGRQGLP-
-ERAAWDALREHVRTIESAGGVVEVVAADVADPEQMRRAVAIAE-ARFGPINGVLHAAGISDDTAIQTLEQATYAAHFQPKVYGLYALEAALGDRPLDFC
VLCSSVSSVLGGLGFAGYAAANCFIDAFTQRHNRTHAVPWVSVNWDTWHLRAGQ--DVT---GLTVAQYEMSPAEGAAAFERVAAARGH-----------
---------------SQIINS-----TGDLDARIRQW--------------VR---LESIRNDAAVAP-APAS---NGRPELSTTYVAPIGEYEQRVSAI
WQHVLGIDEIGLHDNFFDLGGNSLIALQLIARLKKEFKTHISAVALFEAPTVSTMAQYLRPE----------
>tr|A9AV10|A9AV10_HERA2 Beta-ketoacyl synthase OS=Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785) GN=Haur_3966 PE=4 SV=1
------------------KPDIADWFYQPAWVRAELLGAP-VKPGCWLVFADQHGLGNAVGQRLILAGRVVQIEAGSDFVQFDEQHFQIRPGQIDDYQNL
LKTAIGAGYLPTHVLHLWSLAPAA------GRAAIQEYGFTSLLNLAFALGSQDDPVELLVATASIQAVDPSDLPDADNATILGACTVIGQENLSITVRN
IDLSLPADLNSELPVAALVAECQKQNSDLHVAYRGNQRFVQQYQPLRLE---VPESPAVRPGGVYVITGGLGGVGLVLAEHLARTAQAKLVLVGRQGLP-
-ERAAWDALREHVRMIEAAGGSVLVVAADVAMVAGFQRVIAATE-QQFGSINGVLHAAGISDSTAIQLLEQATYAAHFQPKVYGLYALEAALGDRPLDFC
VLFSSISAVLGGLGFAGYAAANCFIDAFTERHNRTHAVPWVSVNWDTWQLKVGQ--DVI---GATVAQYEMSPAEGAAAFERVAAARGH-----------
---------------TQIVNS-----TGDLDARIRQW--------------VR---LESVRADAAAAA-DTAV---QTVPR---GTPLSSSEYEQRVAMV
WQQILGIDEVGIDDNFFDLGGNSLVALQLVTRLKKELKTQIPMVALFEAPTVRAMSQLLRPE----------
>tr|A9AV08|A9AV08_HERA2 Beta-ketoacyl synthase OS=Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785) GN=Haur_3964 PE=4 SV=1
------------------HADVADWFYRPDWAPTALGAP--AAPGRWLILPDAHGLGTAVAASLRAAGTVTL---------------AAGPADAAAYGSL
FATLRADGGLPSHILWLGGLTPLD------SAQAAQATGYYDLLQLAQAVSAQDEAVQLVVVTAGMQAVGANTIPVAEHATLLGLATVIGQENLTIRVRS
VDLAVADDA----AVGLLAAECLATSDALRVAYRDGQRLEETYQPIRLE---APGSPVVRSGGVYVITGGLGGVGLVLAEHLAQTAQAKLVLVGRQGLP-
-ERAVWDALREHVRMIEAAGGVVEVVAADVAQVADLQRVLATAE-ARFGTLHGVLHAAGISDPQAISTLGPKECEWHFQPKAYGLYALEAALGDRPLDFC
VVFSSVSSVLGGLSFGGYAAANSFMNAFTQRHNRTHAVPWVSVNWDTWQLKVGQ--DVI---GATVAQYEMSPAEGADAFERAAATRNE-----------
---------------PVIINS-----TGDLDARIRQW--------------VR---LESVRAAEAPSG-EL------LQSSVASGEMLSLNDYEQRVAAV
WQQILGIDEVGIDDNFFDLGGNSLIALQLVSRLKKELKTQISVLALFEAPTVRAMTQLLRPQ----------
>tr|A0A0H0SSK8|A0A0H0SSK8_9BACL Polyketide synthase OS=Brevibacillus formosus GN=AA984_04320 PE=4 SV=1
------------------EEPAQIQLKNVVWTRPIVVQPAENGEITFEIYSEIDAMDAVMLHNLPSQGDTLYVGEGKVSVSEMENPFVLHPSLMDSYVRY
SANSSADDKVALMLSAVWDVTPVE------KGIAGQDQGVILCFRTIKALLRGRKELGWSIITVQSQPVRHTDVVNPCHASIHGLIGSMAKEYPNWKIRL
LDVEAESEWPLDDMV-----RLPRDRQGRPWVYRQGEWYRQQLLTVD---HPPIDQTRMKQGGIYVVVGGAGGIGEAWTEYMIRTYQAQIIWIGRRQKN-
-EEIQ-------MDRLAAYGPAPDYIAADAAQQNALQQAYEQIK-QTYQRIDGVVHSAMVLVEESLENMQEVGFRAVLSSKVDVSVNIASVFENEPLDFV
LFFSSLMAVTKAPKQSNYAAGCTFKDAYAHQLTQAWPCAVKLINWGYWSSGQVEHQEMVETRLEEIGIGLIQPPEAMQAIETLLAGAML-----------
---------------ADVVISFQVINAGEFDLIIRQT--------------LRNCNLQNVRKDLAEGPSVPLEASTLPIPANA-DRGISTDMLRAYFKQL
VGETLKFDQIDSSAALEEYGIDSIMIVQMTNVLRKKLH-QISTTLFFEYQTIDALVEHFMTT----------
>tr|A0A0F6Y0Y3|A0A0F6Y0Y3_BRELA Beta-ketoacyl synthase OS=Brevibacillus laterosporus GN=EX87_22650 PE=4 SV=1
------------------NENIAEWFYLPTWESAPFTKQEKQENKKYLIFIDEENVGSELANRLRKSGHVSIVRSGAAYSQKSEGEYVIQASEENNYKQL
FQNLRYHDTLPDEIIHMWNVNKDE------IGIASMEFGYYSLIHLVKAISEQIEPLQISVITSQMQKVTDTDRVQPEKAMLLAPVKVIPQEFQNIRCRS
IDIAGTDEQSLKDVIEPLFTELTSKIVDTVIAYRNQGRYVRTFSRVPVE---EATVPQLRKKGVYLITGGLGGIGTKLAEYLAKSIQAKLVLVGRTQLP-
-PRAEWEVLANNIQQMEEYGAEVLVISADVAHENQMRDVIAQAE-DKFGSIHGVIHAAGILRVKSMERITKEKCEEQFQPKLYGTLTLEKVLRDKPLDFC
MLVSSLSPILGGLGFVAYAAANLYLDAFAEKQSLLNPNRWISVNWGDWQYTGKENKTFV---SESIEMLEMTPTEGIKTFQCVLGLKGV-----------
---------------HQVVIS-----SGNLYSRFNQW--------------IN---LEALQEERSGMSGKGKAP-KQQKRIQSMKNRTRMAEIEQLISEI
WMDFYRVGSVNPAENFFQLGATSLDIIQIHNKIVKGLEKHIPIEAMFEFPTIQLLAKHLSGD----------
>tr|A0A0B2B809|A0A0B2B809_9ACTN Amino acid adenylation protein (Fragment) OS=Mumia flava GN=LK11_44245 PE=4 SV=1
------------------VAPHAHPLYHVVWEQQAALAQVAADASPWLIFADASGVGERLAVLLRARGSCSLVRPGPDYVAGAEAGWQVAPERPDDFVRL
LNETAAPG---QRIVFLWALDEAV------GE-------STALLHLVHALVGWSTRPRISVVTRDAVEAGEAGLAQAALSGLARGAMIEHPEWFGIA---
IDLDPAAPE---DETHALLQEMLGESREEQVALRHGARHVARLSPLAQA---ETAALPVDPDAAYLITGGFGALGLHTARWLAARGAGTLILVGRQGAA-
-SDESQRA----IAELRERNVTLRCERLDIADPAAVAAFFAALR-RDGVPLKGIVHAAGIV----IMQVERDELDAVLQPKVAGAWLLHQQSEHFPLDFF
LLFSSIASAWGSREQAHYSAANRFLDALAH-HRRGQGLPALSVNWGPWAEGGMTEAEAL---LRRVGIRSLAADRALDVLNRLPAVPQV-----------
---------------AVVDIDLA-LFQGSYEARGPKP---------------F---LDRVRVAKSAPS-APAMP-ALSDASPRERKRLLADSIDRA----
VAQVLGAGTLDRDLGFFEMGMDSLMALDVRTHLENALGIPLSVALLFDHPTVNALADFLAEQ----------
>tr|D3P6E4|D3P6E4_AZOS1 Polyketide synthase OS=Azospirillum sp. (strain B510) GN=AZL_d03970 PE=4 SV=1
------------------HRTAADWLYRVSWKPSPAMEVTATAPSHWLILADDGGVGQALAARLAQGATCRLLSLDGIAAED------GMAVGAAEFAEP
IDSLIRNAGGGPGVVSLWGLDAHLDPDGDAEIEPARRRAFGNLLLLTQALARHPAVPRLWVVTRNAVSATGTEPQAVVQGGLWGFGRSVSLEAPALWGGL
ADLEAADADGSEVEVAALADHLLRDDGEDQVAFRDRTRYVARFVRQPVPERTTLATAGSSVAGCWLITGGLGALGVETARWLIQRGVRDLVLASRRGADD
PA--AKPVIEMLEG----LGARVTVAKADIGRRKDVQRLLQKLG-RGSVPLRGIVHSAGVLDDATIPQMGWEKFRRATIPKLDAAWYLHRYSRDLPLDAF
VVYSSILSLFGAGGQVNYTSGNGCLDALVTHRR-RLGLPALAINWGPWAAVGLATLSQGEAIWRARGLIYIPPEVGAEALDAVVGSEIEQAATINDWT--
-----------------------------AFARQFTRPPRYYEEVLPAA-------------AVAESAE---PAALPDGLT-----STE---PAQRRSAL
VAATLLTKPVDPTRPLRELGLDSLMAVTLINRVEAGLSVRIPAVVLIRGPSIEELVDEVWPD----------
>tr|M2Z4U9|M2Z4U9_9PROT Phenolpthiocerol synthesis polyketide synthase ppsA OS=Magnetospirillum sp. SO-1 GN=H261_13828 PE=4 SV=1
------------------HRPDESGLYQLRWEEEAAPAAAGGGPAAWLLLGGDGGTGPALAAALAEGAVVRRVVSADVPA------------TPEVMGEL
LRSFAAPAGRRPGIVHLCGLDAAGQAQ---TDETAQRRVLGTALALAGILALFQAGARLWLVTRNAVAASADDPAEILQAGLWGFGRSLAVEMPALWGGL
IDLEAGDDGV-----APLAARLARPDRETQSAFRRGRHLVARLAAIAPPEP--------ESGGTYVVTGGLGAIGRRVAEWLARRKAEVLVLVGRQGGKA
AD--AAAVTRAIEA----IGARVVIVKADMGDRADVRRLMRRVG-ALGPPLRGIYHSAGLVDDGMVEGMDWAQFRRVLAPKLDGAWWLHEASRDAGPCDF
VLFSSVLSLLGSAGQANYTAANACLDALAAHRR-SLGLPALAVNWGPWAEAGMAGGLRAQAVWQARGLSFISSETGGRAFDLLFGGGLGQVAAQVDWT--
-----------------------------AFIGQFAETPPLLAHLQGKV-------------GAGPAAG---LVELRASLA-----SGS---PARRRAAL
TAAALLSEPIEPGRPLREVGLDSLMAVTLTNRIEAAAGLLIPTFNLIRGPSIDQLIDELWPD----------
>tr|Q2W5X2|Q2W5X2_MAGSA Phenolpthiocerol synthesis polyketide synthase ppsA OS=Magnetospirillum magneticum (strain AMB-1 / ATCC 700264) GN=amb1949 PE=4
------------------ADGEDGWLYVPRWDDRPVPPVKASGPLTWLLLGGDG--AKPLKEALRTGAACRLVAAKDCPT------------DLEGFSRL
LEGFAAEAGAGKGILHLGAVDAPGEEA--WGDEGAQRRLYDSVLGLSRALGGFLVAPKLHLVTRNAADATGTEPAHVLGAGMWGMGRSLALEAPALWGGL
IDLEAGGASGAE--AQLLAAHLAAADDEAQVALRGGKRLAARLVRAPVPER--------GEGGTYLVTGGLGALGVLTAEWLAARKAAHLVLVSRQGDKA
AN--AAEVLARLEA----LGAKVTIAKADIAKEGDVARLLGRLA-KAEPALKGIYHSAGVLDDGLVDQMDWTKFRRALAPKLDAGWWLHKHSQGLKLHDF
VLYSSVLSVIGSAGQTNYTTGNACLDALAAHRR-ALGLPALSVNWGAWASAGMADGLQGEAIWRARGIHYIEPDLGREAFDLLFDGAAGQAVLPADWP--
-----------------------------TFLRQFQVPPRFYAELQGGA-------------VGGLAAD---IEALKQAMA-----APE---PGIRRAAI
TDTTLMTAKVESDRPLRELGLDSLMSVTLINRVESATGLRIPAVKLIKGPSIDELVADVWPD----------
>tr|A0A0F5A735|A0A0F5A735_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. MUSC164 GN=VT50_27160 PE=4 SV=1
------------------Q--PYESLYQVEWVPTAPDTFVASGAGRWALVGPDLGAADVTVDTH------------P------------------DLAAL
AVAIDAG-ATAPVVLAAQVSR------TRPELAEAVRAGHRALDLLKGWL-DEFGASRLVFLTRGAIAAGAD-VADPAAAAVWGLVRSAQSEHPGRFV-L
ADLDDHDGS--R---RILPAAL---ADEPQFVVRDGEVLAGRLARVPAPG-TVTSGPTWDPRGTVLVTGAASGLGGLVARHLVGHGVRHLVLVSRRGLAA
DG--AAELRTELAD----LGADATVAACDTADRDALAALLAALP--DEHPLTAVVHTAGVLDDGVVE-LTPERIDRVLRPKVDAVLNLHELTAGLDLSAF
VLFSSLSGTLGGTGQANYAAANAFLDAFAQRRR-AEGLPAQSLAWGLWEERSGMTGKAHMRRLAREGVTPMASEEALALFDTACGIDT-ATLARLNAS--
-------------------------------AWRAQDGPALLRGVIGPAKSTG-----GSGA------D---SAELRRRIG-----SMN---PAARRQAL
LERALHDNARMPDRGFLELGFDSLTAVGLRNQLGTATGLRLPATLLFDYTTSRALAGYLADE----------
>tr|W4M159|W4M159_9DELT Uncharacterized protein OS=Candidatus Entotheonella sp. TSY1 GN=ETSY1_00130 PE=4 SV=1
--------------------PAMDWLYDITWQPMPYS-PGSVQSGSWLVLAGETGLGKTLAARLARGQRCVLVSASQADQTG-------------LADLL
RGSM-GAGQPPCGVVYLWGVDTDSTPAEL---PELTHRLCVQVLDLVQAI-E--MTPQLWLVTQGAQAVGKTDRLQVQQAPLWGLGRTIAREHPELQCVC
LDLPADATSEDNA--HTLFEAL--TDAENQIAYRQGTRYVARLVR------RSGIPLPIHETGGYLITGGLGGLGLRVAQWLVAEGARQLVLCGRQGAAT
PA--ARQAVEALQQ----IGAKVVILQADVAVQNDVVRMLTAA--QELAPLRGIIHAAGVLDDGILLQQSGARFATVMTPKVAGSWHLHQLTEIIPLDFF
VCFSSTASVLGAPGQGNYAAANAFMDALAHHRR-ALGLPGLSVNWGGWSEVGLAAASN----EPSSGIGAIPPEQGVQVLGVLLRRETAQATMPVDWT--
-----------------------------VLRQQFPSRDPL---LTLQQ-------------DGSEHRL---RGDELARLQ-----TAD---TVTRQQLL
IAQLLAGASGGAEMSLTALGLDSLMTIEFANRIKAELAVSVPVRKFLEGTSIAQLAQYLNTL----------
>tr|A0A0A4GSQ2|A0A0A4GSQ2_9PSED Uncharacterized protein OS=Pseudomonas mediterranea CFBP 5447 GN=N005_01590 PE=4 SV=1
------------------------WLTTVEWVPQPSRTPDQSPGGMWLFIGGTGELVQGIGKGLSNDGPVVHALFADDCRRVSAHLWHIRMGFPEDLHEL
FQSLPVSAQCPLGVVHLGGTDPIAAQDRREQEDLAPLTGLYSVVATLQALAASSEVARFWIVTRAAVNVRSA-LISVAQAPLWGLAKVIAQEEPAAWGGF
IDLPPDLEDV-LSLAAQLML----GQEDQFAIRQGGVHVPR---LVEASP-VKSRHVALSPQATYLVVGGFGGLGREVLAWLVEKGARHLAVIGRKSLDA
TGST---VLESFRH----QGVSIDYLRLDIATGEAAETLASYIG-TLQWPLRGVLQLAGTVEDAVLSKLSASSLHHVLLPKLQGTQVLDRVTRDQPLDFF
IGFSSISASLGFKGQANYVAANSAMDAIMENRV-SSGLPGLSIAWGPWSSEGMASRVFLSALGI----NFISAQAGLQRLWDNL-SAQGVMGAPIDWK--
-----------------------------PYKAHLQSSN--YLSLI---ESTAE---GDTVP-------------FLDTVS--------SLDGEQRQAFI
LGGGFDA--DAMDKSLTMMGFDSLMTVEFRNSL-KKLGINFPLGRLIVGATLNDIGDFVLEH----------
>tr|W7YD27|W7YD27_9BACL Malonyl CoA-acyl carrier protein transacylase OS=Paenibacillus pini JCM 16418 GN=JCM16418_325 PE=4 SV=1
-------------------AVSSAECYQPRWVPAPIALAEPQVTGTVLLWMDDQGIGSSLSELLSKGRHVIELFEGEQYEQISDDSYSLSLS-EEHFIQM
WEDVREAG---VHFIYLGALSGPDHAKERTE-LALQMRGVHGLFHLARSFAKWKLPLEWLVVTSGAVVVDGKEVIRPHHAAMAGLGKVLNQEFPNLQVRF
MDMDEVLPEVS------IEQEL-LEERDFHVAYRDGIRYTLEIAPLKQNL-RADHEVVVKAGGTYLITGGTGGIGLELASYLSSLAPVNLILINRSLVPE
RQEARITRLQAIEN----NGSQLHCYRADVSDEAEMISVLEEVS-RDYGPIHGVIHAAGVAGDGMILRKESAVFTNVLAPKIQGAWLLDKYVNSEHLDFF
VLLSSVTAITGGLGQGDYTAANSYLDAFAHHRR-LEGKPALSINWPAWKETGMAVNY----HDAPAVWKSLATHKALQYFDLLLHSGVPQAIGELDMETT
----------------------------ANLIDQLPFRF----------SKVESGIITDPLQYTNQSAQ---AVLTLTGKS-----ETDISPLEQQVAQ-
--TVLGL--EEVYESFYDMGGDSILAAQLYRKLDQHFPQTVDISDIFSYPSVIEMAEYLDSL----------
>tr|D7F198|D7F198_9CYAN Polyketide synthase OS=[Oscillatoria] sp. PCC 6506 GN=cyrC PE=4 SV=1
------------------QAQIYDWLYEVVWQPQLLPLSVATEGRQWLIFADASGYGEALAAQLQQGDITTLVYAGQEYRSANNEYFRIDPTQGEDYERL
LAVL-----PRLGIVHLWSLDIPSLDR--SDLIENVQLNTGTLLHLLQAV-E-TRTPSLWLVTNNAQAVRKDDVVGVLQSPLWGMGKVIALEHPELNCVS
IDLDREGLPNEQA--KFLAAELTAIPHESQVAWRNGTRYVARLKRY-----ATSPKMLIRPDATYLITGGLGSLGLLVARWMVEQGATHLVLIGRGQ-PQ
PA--AQQQLQEIAA----LGATVTVAQADVGIRSQVADVLAQI--DKAYPLAGIVHAAGVVDDGILLQQNWARFRKVFVPKLEGAWHLHTLTKEMSLDFF
VCFSSSAGLLGNAGQANYAAANAFLDAFAHYRR-RQGLPALSINWDAWSDVGMAARLASATVGQDSSTLEIAPEQGLQLFAYLLQPS-AQIAISTDG---
------------------------------LRTMYDT--AFFALLNQEQ-------------STPPHEV---GPTLLEQLQ-----QTR---PKEREKML
LRAVLSPELPAVHQPFTELGMDSLMSLELRRRLEESLQIQMPATLAFDYPMVDRLAKFLLTQ----------
>tr|A0A0R0MCJ5|A0A0R0MCJ5_9NOST Polyketide synthase OS=Cylindrospermopsis sp. CR12 GN=ASL19_09690 PE=4 SV=1
------------------QKPICDWLYEVVWQPQLLTLSVETEGRQWLIFADASGHGEALAAQLQQGDIITLVYAGLKYHSANNKYFQIDPIQREDYERL
FAAL-----PPLGIVHLWSLDILSLDK--SNLIENVQLGSGTLLNLIQTV-E-TPTPSLWLVTKNAQAVRKNDLVGVLQSPLWGMGKVIALEHPELNCVS
IDLDGEGLPDEQA--KFLAAELTTIPHESQVAWRNRTRYVSRFKGY-----APSSKMPIRPDATYLITGGFGGLGLLVARWMVEQGATHLFLMGRSQ-PK
PA--AQKQLQEIAA----LGATVTVVQADVGIRSQVANVLAQI--DKAYPLAGIIHTAGVLDDGILLQQNWARFSKVFAPKLEGAWHLHTLTEEMPLDFF
ICFSSTAGLLGSGGQANYAAANAFLDAFAHHRR-IQGLPALSINWDAWSQVGMTVRLASTTVGQDSSTLEISPEQGLQIFAYLLQPS-AQIAISTDG---
------------------------------LRKMYDT--AFFALLDQEQ-------------STLSHEV---GLTLLEQLQ-----QAR---PKEREKML
LRAVLSPELPAVHQPFTDLGMDSLMSLELRRRLEESLGIQMPATLAFDYPMVDRLAKFILTQ----------
>tr|B5X0I3|B5X0I3_STIAD CrpB-like protein OS=Stigmatella aurantiaca (strain DW4/3-1) GN=dkxI PE=4 SV=1
------------------ADSTRELLFELAWREQRASQEVVSPPGHWLLFADSGSVAERLKELVQHSRTCVTVSPGAGYEKLGRDHYRLDPADPAGFDRL
FQDL-SAGGVAPTVAYLWGLDER-GAAELEELAGVTARSSAGALHLVQAM-AWAQRPALWMVTRGAVAAVPSDVGGLSQTPIWGLGRAAAIEHPELGCRL
ADLDGDEGAPARL--FQLMAE------------------------------SRSSPVRIRSDGTYLLTGGMGALGLATAEWLVEEGARQLVLVGRGE-PG
EA--VKARINALTA----RGCHVTVTRADVSRREEVQRLVEGIS-ARESQLLGIFHIAGVLDDGVFMLQSRERIAQVFVPKVLGAWNLHLATAQLPLDLF
VMYSSAASLVGVAGQANYVAANSFLDALAYHRS-RQGLPALSVNWGRWSGEGMAAKTK--GSTQGVDAGNLSPRRALQILGDLLMLDVVQMGVSFAVA--
-----------------------------AVDSAL-SPGPLFSELMEQA-------------RSSSVAR---MHELLGELK-----SAD---SVRRRGLL
THPLLFAPDHEKKVSLNEMGLDSLRAVELKNRIGRELGVDLPMARFIDGTNLEGIVEALHSQ----------
>tr|S9NWG4|S9NWG4_9DELT Malonyl CoA-acyl carrier protein transacylase OS=Cystobacter fuscus DSM 2262 GN=D187_009448 PE=4 SV=1
------------------SDSWRESLFELVWREQRAPWAIPTRPGRWLLLADSGGVATQLKERVQHSGTCVTVTQGAGYERIDPSHYRLDPTDAASFDRL
LREV-SEGGAAPVVACLWGLDER-GATELEGLADATARGTAGVLHLTQAM-TWAQRPVLWLATRGAVAAAPADVEGLAQVPIWGLGRAAAIEHPEFGCRL
VDLDTHEDAPARL--FQLIVE------------------------------SRATPVRILADGTYLITGGMGALGLATAQWLVRSGARHLVLTGRGE-PG
DE--AKATISALTA----SGCQVTVARADISRPEDVQCLVEEIS-ARGPRLRGIFHSAGVLDDGVMLLQDRERFSRVFAPKALGAWNLHLATAQLPLDLF
VMYSSAASLIGVAGQANYVAANGFLDALAHHRS-RRGLPALSINWGRWAGAGMASKTR--GGISASDASSIPPQQALRILEELLAREVTQMGVPFNVS--
-----------------------------ATEATA-SPGPLFSGLMEQP-------------RSVGASR---MHELLDELK-----RAD---STRRRVLL
ARPLLFAPEHEKEISLNEMGLDSLRAVELKNRIGRELGVELPMARFIDGTSLDGIVEALHTQ----------
>tr|A0A0F7BMW2|A0A0F7BMW2_MYXFU Polyketide synthase OS=Myxococcus fulvus 124B02 GN=MFUL124B02_24075 PE=4 SV=1
------------------ADSSRELLLELAWRELEAPRAASLQSQRWLLLADSSGVADGLKVQVRRGGTCVWVTPDA---SDEPGHVHVDPNQPEGFVRL
LQSL-SEEGAAPTVVCLWGLDEP-GAEALES-----TRSATGVLHLVQAM-SWAQRPALWLVTRGAVAATPGDVDGLAQSMLWGLGRAAALEHPELGCRL
VDLDEGEDAPARL--FERMTR------------------------------NSANPVGVHADGAYLITGGLGALGLATAAWLVDAGARHLVLVGRGA-PG
EA--TKLRLDELGA----RGCEVTVARADVSRLDDVRRVLEEVS-ASGTRLRGIFHVAGVLEDGVFLRQDRERLARVLAPKVMGAWNLHHATAGLPLDLF
VMYSSAASLVGVAGQANYMAANTFLDALAHHRR-AKGLPALSVNWGQWAGGGMAQKA----RTATSDATSLPPQRALRILEELLGRELTQVGLPVDAS--
-----------------------------TQGASL-SEVPLFSELVGKE-------------PSASTGR---MVELLEEFT-----RSD---GARRRGLL
THPLLFPPEHEKKISLNELGLDSLRAVELKNRMGRELGVDLPMARFIDGTGVAGIVEALHEQ----------
>tr|Q1D4F1|Q1D4F1_MYXXD Polyketide synthase OS=Myxococcus xanthus (strain DK 1622) GN=MXAN_4297 PE=4 SV=1
------------------SGAMQELLFELAWREQPAPSAVASQSGPWLLLVDSDRVADEVRTLAQRAWICVVATPGASYERVDANHYRLNPHDAAGFDRL
LQDV-S----APAVAYLWGLGDR-S----EALSGAVTSSTLGALHLVKAM-GWAQPPALWMVTESAVAATPTDVEGFAQASLWGFGRAVAIEHTEFMCRM
VDLEPGSESLERL--FLLMAQ------------------------------ERAAPVRIRPDGVYLVTGGLGALGLETAEWLVGAGARHLLLVGRSE-PT
DA--ANARLAALTA----RGVGVTVARADVSRQEDVQRLVASVS-ERGLSLRGIIHTAGVLEDGVILHQDAERFSRVFAPKVQGALNLHRATAGMPLDLF
VMYSSAASLVGVAGQSNYVAANSVLDALAHHRN-RLGLPALSINWGRWAGAGMAAKS----RPEASDAASLSPEVALQVFEQLLEQGAVQVGVPFSVS--
-----------------------------SLEAGP-SPGPLFSELMEQA-------------RSAAASR---MHELMEELK-----RAD---GERRRALL
TRPLLFAPDHEKRISLNEMGLDSLRAVELKNRIGRELGVDLLMARFIDGTTLDGIVDALSTQ----------
>tr|F8CN02|F8CN02_MYXFH Polyketide synthase OS=Myxococcus fulvus (strain ATCC BAA-855 / HW-1) GN=LILAB_29635 PE=4 SV=1
------------------SAATQELLYELAWREQPAPTAVATQAGSWLLLVDSEGLAREVQALAQRSWRCVVATPGTGYACVDAGHYRLDPYDAAHFDRL
LQDV-SADGAAPAVACLWGMGDR-S----EARSGALTASTVGALHLVKAL-PWPHRPALWMVTEGAVAATPTDVEGFAQAALWGFGRAAAIEHTELACRM
VDLEPGAEALERL--FHLMAQ------------------------------GGTAPVRIQPEGVYLVTGGLGALGLATAEWLVGAGARHLLLVGRGG-PS
DA--ANKRLAALTA----RGADITVARADVSRLEDVQRLVAGVA-ERGQHLRGVIHTAGVLEDGVILHQDRERFSRVFAPKVRGALNLHRATVGLPLDLF
VMYSSAASLVGVAGQSNYVAANSVLDALAHHRR-HQGLPALSLNWGRWAGAGMAAKS------EASDAASLAPEVALQVLEQLLEQGAVQMGVPFSVS--
-----------------------------SLESGP-SPGPLFSELMEQA-------------RSAGASR---LQELVDELK-----RAD---GERRRVLL
TRPLLFAPDHEKKISLNEMGLDSLRAVELKNRIGRELGVDLLMARFIDGTTLDGIVDALSNQ----------
>tr|A0A0H4WWG6|A0A0H4WWG6_9DELT Malonyl CoA-acyl carrier protein transacylase OS=Myxococcus sp. (contaminant ex DSM 436) GN=A176_002592 PE=4 SV=1
------------------SGAMQELLFELAWREHAAPAGVANHPGACLLWVDAGHDAEAVRALAERAWSCVVVTPGPAYEHVEPGLYRVDPMDPAGFERL
LQDV-VAAGTVPTVAYLWGRSER-A----ESPSGEVPWNTVGALHLVKAL-NWAQRPALWMVTEGAVAVAATDVDRFTQASLWGFGRAAAIEHTELRCRM
VDLEPGDDALARL--FHLMAE------------------------------EQAAPVRIQPEGVYLVTGGLGALGLATAEWLAGAGAKHLLLVGRSA-PG
DE--AKARLQSLSS----RGVDVTVARADVSRWDDVQRLVDGVA-ERGSRLRGVIHTAGVLEDGVILHQDRTRFSRVFAPKVQGALNLHRATAGLSLDLF
VTYSSAASLVGVAGQSNYVAANSVLDALAHHRR-RMGLPALSINWGRWAGAGMAAKS----RGEVSDGSSLAPELALQVFEQLLEQGAVQMGVPFSVA--
-----------------------------SLESGP-SPGLLFSELMEQA-------------RSAGASR---MHELMEELK-----RAD---SERRRALL
TRPLLFAPDHEKKISLNEMGLDSLRAVELKNRIGRELGVELLMARFIDGTTLDGLVDALHTQ----------
>tr|L7UHB6|L7UHB6_MYXSD Polyketide synthase OS=Myxococcus stipitatus (strain DSM 14675 / JCM 12634 / Mx s8) GN=MYSTI_06012 PE=4 SV=1
------------------SDSARELLFELAWREQA-ARTLPLLSGRWWVLADAGGAAHALKEQVRHGGSCEVVTPGPGYERSEPGLTRLDPSAPEGFTRL
LTEL-SSEGAAPTVVCLWGLDEP-EAEALESLAGATSRSAAGVLHLVQAM-SWAQKPVLWLVTRGAIHAAPGDVTGLAQSTLWGLCRAAAIEHPELSCRM
VDLDDSEDAATRW--FERLTV------------------------------NRASPVSIQADGAYLVTGGLGALGLATAAWLVEAGARQLVLMGRGA-PG
DE--AQARLEALRA----RGCEVFVARGDVSRLEDVRRVVEEVS-ARGSTLRGLFHTAGVLEDGVFLRQDRERLARVFAPKVLGAWNLHQATEGLPLDLF
VMYSSAASLVGVAGQANYVAANTFLDALAHHRR-AKGLPALSINWGRWSGGGMAEKG----PGRAPDATSLSPQRALRVLEELLGRDLAQVGVPVNLS--
-----------------------------SVEATP-SAGPLFSELAEQA-------------RSVTTVR---LVELLEEFK-----RSD---GTRRRGLL
KHALLFPPEHERTISLNEMGLDSLRAVELKNRMGRELGVDLPLARFIDGSGLAGIVEVMHEQ----------
>tr|I0J6Y8|I0J6Y8_SORCE Polyketide synthase OS=Sorangium cellulosum GN=pelB PE=4 SV=1
------------------QDALEGCVHEVVWRRAERLP-SLGATGAWVVFSDR-GVGAGLHGRLGAGQRCVRVFAGEGYEQIEPDLYRIDPGKRDDYARL
LREAFGEEGS-CGVVHLFSLDAAPIEAATEALAAELAGGSVSAAYLTQAL-HGRDAPRLFLVTRGAQGVHEH-AVSVGQAPVWGLGRTIALEHPEVQCTR
IDLAPGASEADA---ARLAREL-----EDQVALRGD---------------S-ARRFSLRPDASYLITGGLGGLGLSLARWLVEQGARHVALVGRRGAGP
EA---QQAIREMEE----AGARVLVEPADVSCRDEVERLFARVE-EKLPPLCGIVHAAAVLDDHTLLEQSEESFRKVFGPKALGAWHLHALSEGRALDFF
VMYSSGASLFGSPGQGNYAAASAFVDALSRERA-RRGLASMSIQWGAFAEVGLAAAQNRGKRLSSRGVASFTPAEGLEALRRLLLNPRAEVGVRFDAR--
-----------------------------QWSEFYPVAAPLFAELTD-REAP--------RV------R--------QALE-----EAA---PHERLPLL
ERAVLRLDPRRRGAPFQSLGMDSLMSLELRNRFEASLGIRLSAILLFTYPNVSALSRHLLAM----------
>tr|D6U8P2|D6U8P2_9CHLR Acyl transferase OS=Ktedonobacter racemifer DSM 44963 GN=Krac_0080 PE=4 SV=1
------------------RQRLNQLLYSIQWEQQVSTE-VQESRKRWLIFGAH-GPAQKLVEYLANGAECIVVTPGNTYKQVQVQHYELNPTSPEEFHHL
FSELYQGGQT-IGIVYLWSLLTQPVNEASHALFEDQELVSIGTLHLLQAL-TKETTPRLYLVTSGVHAIEEQ-TTALSQAPLWGLGRVIVYEHQDLHATL
IDLDPTPSEESI---KALCKEI-----ADEVALRGK---------------QESSETLFRQDGTYLITGGLGGVGLRTAQWMIEQGARSLVLMGRRGPSE
EA---QATLHMMRD----TGATVHLMLADVSQEEQLALALDEIR-RRMPPLRGIFHSAVVLDDSTLLQLDRERFQGVMPPKVDGAWNLHRLTLNDPLDYF
VLFSSAASLIGSPGQGNYAAANAFMDMLAFYRR-QQGLPALCINWGRWGEVGQAM-KDRGERLDVRGFASMKPKEGLAILGELLRQSPPQVGMSFHLP--
-----------------------------KWSQFYPNLTSLFADLVAGAAEP--------RL------T-------GDMLV-----TLD---EEARHQAL
SQSVLGHASLNAYQPLNRLGIDSLMSVELRNRIRADLDVTIAVTTFLKGVTFEQLIGEILEG----------
>tr|D2AZU2|D2AZU2_STRRD 6-deoxyerythronolide-B synthase OS=Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100) GN=Sros_4286 P
------------------ERKAGRLLYGVEWAELEPLT-VP-ERAPWLVVSDS--LGAELCASLAAGGEPLLVQPGAGYRRLGPHRCVLDLASTEDWTML
IKEQSESGAW-PRAVVRL-STAPPVEEATDALERS-----YEVLALVKGL-SDQAAPRLWLVTTAAQTPDGS-DVNPAETAVWGIGRVIPYEHPELRCSM
IDLPEDPDSGIL---RALSAEI-----ETEIALRDG---------------S---PVPVRPDGTYLITGGCGGVGLLTAEWLVKNGARHLVLVGRGGAPE
GV---TDRIAAMRS----AGAQVLIARTDIASRVAVADLLDDIA-RHMPSLRGVVNSAVVLDDGTLAQLDRARFLAPMPPKVHGSWHLHELTRHLPLDFF
LLYSSAASVIGSPGQGNYSAANGYQDGLAWHRR-ANGLPALTVNWGQWSATGQVA-KSKDLRLNERGFAGFAPAEGLAVLDRLLPSLHAQASMSFDPT--
-----------------------------AWTHYFPALRSLLRHLVP--AA---------EL------E-------PADLA-----GLG---NEQAEQLI
AAAIVQLPRAKAAQRPHRMGLDSLMAVQLRNRIAADLGVTLPVAVFLQRRTIGDLATVTLTH----------
>tr|A0A0C2PTN1|A0A0C2PTN1_9CYAN Uncharacterized protein OS=Tolypothrix campylonemoides VB511288 GN=SD81_24665 PE=4 SV=1
------------------SESIHDWFYEVEWRPQARLEIETSAAKNWLIFTDNLGVGQQLAAQLTLGDICTVVTAGQQYQQLSPTHFTINPEQKEDYSLL
LEQI-AISTPDIGVVHCFALQGAQTSTLTTALEAESQLGCKTTLMLVQAL-KSLHKPRLWLVTRGAQLLAPDHMSAIAQSSLWGMKKAIALEHPEFRCTC
IDLDASATISEQA--HALLAEV--FDLEDQVLLRKDTRYVARLVRSRSLSRESGTGLSCHPEGTYLITGGLGALGLLVARWLVERGARNLVLLTRSR-PN
PQ--AQTQLQSLEQ----TGVRVEFVQADVSNYDSLAQAFSHIQ-QSLPPMRGIIHSAGVLDDATVLQQNWEKFATAMAPKVQGAWHLHQLTQTQPLDFF
VLFSSAASLLGSPGQANYSAANAFLDALAHYRS-SLGLVGQSIHWGAVSQVGMAARRD--VLVQKYGMGVISPPQVLEALSLVLHPTVVEVGVPIQWS--
-----------------------------QGLQ------ANWSFLAQQI-------------LTATSAT---ESEFLQQLK-----AAT---PNRQRNML
MSKILIKQAYSPRQRLFDLGIDSLMAVELKNLLESQLNCSLSSTLVFDYPTPQVLVDYLMSQ----------
>tr|D0LS56|D0LS56_HALO1 Acyl transferase OS=Haliangium ochraceum (strain DSM 14365 / JCM 11303 / SMP-2) GN=Hoch_1186 PE=4 SV=1
------------------NASLDGWLYENAWREAPRQA-EAGAEGTWLVVTEHEGLGEALCAALKRGGSCIVASMGASFADRGGDNFELDPEVAGDWSQW
LSAARAAAASDIGVVYLPAATALA-GEPLETALAAQRLVTVAPLLLTQAL-AGRDPPRLLLITRNVWAGDDA-PSACAQAPLWGLGSTVDFEHPELRCTR
IDLGAQSAADAA---EDIVSEIVSSHDERAIKLHGDERQVLRLTQVRPDEPSVLETGQMDSEKSYLITGGCGGLGLSVARAMVQRGARHLMLLGRSGGND
AS---ARAVAEMEA----EGAELRVVAADVADEARMGEVIAELR-ETMPPLGGIIHAAGILDDAVITHLDVARLHRVMAPKMLGAVNLDRLTRDCELDFF
VLFSSATTLIGSPGQANYCAANTFLDAFAHHLR-ARGRRALSINWGAWTEVGLAAAQNRGARLEHRGLGAMNPEQGAEAFLSVLSSAHAQIGMSLDVR--
-----------------------------QWQQYYPKAAPLFSELGAKGEN---------EF--------------VSALR-----AAP---AAQRAMLM
EEEVLRIPADRADASFRGLGLDSLMAIEFRNRLESISGLTLSATMVWSYPTPRALAAELLRR----------
>tr|Q6V1N9|Q6V1N9_9ACTN Plm5 OS=Streptomyces sp. HK803 GN=plm5 PE=4 SV=1
------------------GA-DATSLYTVEWPVKELPE-DGSAARTWALIAAAEGVE---LSHC------------T------------------SLPAL
AAALDATDAPVPAVLVPCFLPHSPGCPPDADLVERAHYAATVLDLVRTWL-DAFEASRLLLLTRGAVTPDAGHLSDAVGSLAWGLVRTVQNEHPGRVL-V
ADLDDDPAS--W---SVLPGVL---HEEPQVAVRRGVAHVPRLTPAR----AAERPAPFDSMGTVLVTGGTGGLGSLLARHLVVHGVRHLLLTSRRGPQA
PG--AAELAAELIE----LGAQVTVAACDMADSDAVEELIGSLP--AGHPLTAVIHTAGVLDDGLVE-LTRERLNTVLRPKADAAVVLDRLTRHLDLTAF
VLYSSVGGTFGGPGQGNYAAANAFLDAVAHRRR-AEGLPGLSLGWGLWSDTTGMAAETHVDRLNRSGLVTMSPAEGLALFDAAISGEYGPVVVRLDLP--
-----------------------------ALKARATSGASVLADVVGPARAAK-----SGTV------S---GAALRTSLS-----ELP---EDERRRML
LDAVLHHQDGTDEQPFKDLGLDSLTAVELRNRLASATGLTLPATLLFDLPSPSALAHHLLTR----------
>tr|A0A0E9AG82|A0A0E9AG82_MYCTX Phenolpthiocerol synthesis type-I polyketide synthase PPSA OS=Mycobacterium tuberculosis GN=ppsA PE=4 SV=1
------------------YCDATNFVHTIDWQPQTVP--ATHPGAEQVTHPGPV-IGDDGAALC------------------TLEGAGYQPA--------
---VMSDGVSQAYVVYVADSDPAGAD--EVDFAV---RICTEITGLVRTL-RDDKPAALWILTRGVHE--SV-PSALRQSFLWGLAGVIAAEHPELWGGL
VDLAINDDLGEFG--PA-LAEL--KPSKSILVRRDGVVLAPALAPVRGE--PARKSLQCRPDAAYLITGGLGALGLLMADWLADRGAHRLVLTGRTPLPP
RRDRRIDAIRALEM----RGVTVEAVAADVGCREDVQALAARDR-DGAAPIRGIIHAAGITNDQLVTSMTGDAVRQVMWPKIGGSQVLHDAFPPGSVDFF
YLTASAAGIFGIPGQGSYAAANSYLDALARARR-QQGCHTMSLDWVAWRGLGLAA--AQ-LVSE--ELARM------GSRDIT--P------AFTAWE--
-----------------------------FVDG-YDVAQVVPMPAP---AG---------ADG-SGANA---YLLPARNWS-----VMA---ATEVRSEL
EQAELRVPEKETDRPFAELGLNSLMAMAIRREAEQFVGIELSATMLFNHPTVKSLASYLAKR----------
>tr|G9NQL7|G9NQL7_HYPAI 6-methylsalicylic acid synthase OS=Hypocrea atroviridis (strain ATCC 20476 / IMI 206040) GN=TRIATDRAFT_45540 PE=4 SV=1
-------------------EDSGSLVHQLVWVPPAFKEQR--DLTHVIMVSSDL-LLEAYSTQL---NKVTRVTCRNRV---------------VELSDL
SAAL----SEKGIVVYAPPAIESAAQVADEE-------FIWQTASIVKALAIGSVLAKFFVLTNRVFSGE---VTSLAHGALYGLARIIASEHPDIWGGL
IDSESSSDFPMLA--IRYVD------DYDILRINDGLPRRAIMRR------GIANTLMPKPEGTYIVTGGLGDFGLETCNFLIEKGARNVVIVSRRGLPL
PNYAVINRIRAFEA----QGATIHTLALDITLPDAADLLKAIRA-LNIPPVLGVVHAAGVLEDSSLVETTRDSFARVLAPKVNGALALHSAFPPGSLDFF
IMYSSIGQLVGTVGQASYGSSNAFLDALATHRR-AQGDNTVAFQFTAVRGLGMATGTLLMTELRSKGITDITAGEAFR-----------------AWE--
-----------------------------HLGRYDVESATRCLPLL---LLEDIVVTAANSM-ATVTTN---NDTIDDGTV-----PAH---PLDREKWV
DKRVLMMDDIDLQTRLSDLGLDSVMTVALRQAFQAVFKIKVPLTLTWSHPTLKHLVPWFLSR----------
>tr|U5WV50|U5WV50_MYCKA Polyketide synthase OS=Mycobacterium kansasii ATCC 12478 GN=MKAN_24040 PE=4 SV=1
------------------SSDARSFVHTIDWQPRVDVV-QAHPAPGRLTGPQPV-IGDDGAPLR------------------HLENAGYPPA--------
---A----VSDAYLLYVADSQPATAE--EVDFCV---RVTAEIGSLVRTL-EGERSAALWIVTRGVHE--SV-PSALRQSFLWGLAGVIAAEHPELWGGL
VDLPAGADLAESA--PI-LAEL--APSKSILVARDGVVLTPALAPVRGT--PVRQPLQCRPDAAYLITGGMGALGLLMADWLADRGARRLVLTGRTPLPP
RRDKKIGAIRALEM----RGVTVEAVAVDVGCREDVQALTKRDR-DGAAPIRGIIHAAGVTNDQLVTQLTEDAVRQVVWPKVAGSQVLNEAFPAGSVDFF
FLTASAAGIFGIPGQGSYAAANAYLDALARARR-QQGCHTMSLDWVAWRGLGFAA--AQ-IVSE--ELKRM------GSRDIT--A------AFTAWE--
-----------------------------YADG-YDVAQVVPVPST---AA---------VPGAVGAAA---HLKPAQDWS-----QMP---ATAVRTEL
EKAELRLPETDTDRPFAELGLNSLMAMAIRREAEQFVGIELSATMLFNHPTVATLARYLTNR----------
>tr|A0A0C1XZX4|A0A0C1XZX4_9CYAN Polyketide synthase OS=Hassallia byssoidea VB512170 GN=PI95_00105 PE=4 SV=1
------------------RPDLADWFYIPSWKRSMPPQSKN-QPEYWLIFVDECGLSEKMVQQLLAGQDVITVKIGEQFERESECRYTIHPQQQDDYDTL
FKELRQLNKIPDKIVHLWSVTPDIEAE--IELQEKIELGFYSLLFLAQAIGHN-TDSQVTVISNNMQAVTGT-VLCPEKALVLGPCQVIPLEYPNISCRS
IDIVVPKSESSQQLIDQLLAEL--QTCNQVIAYRGLHRWVQDFEPVRLDA-TVAENPRLRERGVYLITGGLGGVGLTLAEYLAQSIQAKLVLLGRSPFPE
PDESKIRKLQSIEA----LGSEVMVIGADVANSEQMSVAIAKVN-QRFGQINGVIHAAAVFGGGMIQLKTKEDAANAIAPKVRGTRVLEALFKQTKLDFF
VLCSSLSSFAGASGMVDYTAENAFLDFFAHYSA-SKYGFIKSINWDRWNSLGMAVPVH---ITGEELTGGMTTFEGI--------------------E--
-----------------------------AFRRILCSSTQVFSSLIL--EEKLAQLPTHSRP-------------NLANAY-----VAPGNEVERSLAEI
WQQLLGI--EQIHDNFFELGGDSLFATQLVSQLCKTFQIELSYKGFFNGPTVAELA-IIVQK----------
>tr|M4TB58|M4TB58_9NOSO Polyketide synthase OS=Nostoc sp. 'Peltigera membranacea cyanobiont' PE=4 SV=1
------------------KPNISDWFYLPTWKQAKLLEPTK-QKQCWLVFLDSCQLGSQIAQQLQQGQEVITVTVGEEFSQLSDRTYAINPQCRHNYDAL
FQALRAIEKIPQTIAHFWGITANIESEIS----FGQHIGFYSLLYIAQALSQNTTSVEIMVVTNNLYDAIGQ-KLIPEKGTILGTCKVIPQEYPNLTCRN
IDVIIPESGNFNQIIEQLMVEF--QSNDLVVAYRSSHRWIQIFESTQIPE-VVEETTRLKTGGIYLIAGDAGNLGLTFTEYLAQTVQAKLILIGNIGLPQ
RNENYIKKILALEE----LGTELLIIEADVANVEQMQAAIHQSY-DYFNQINGVFYVTPM-GNKSTQEISQTETESLFHSKVDALYVIEKVLQGKELDFC
LVQSSLSSVVGGLGLVAYSAANLFTDAFVNKLN-QISSPWFSVNWDAVKYEEKPE---NIAFGADLNELVMTPKEAW--------------------D--
-----------------------------VSLRVLSMGSQFLQIRLLKHPDNSQDISQHSRP-------------NLQTPY-----IASSNEIEQKIVSI
WQELLGI--EKVNDNFFELGGHSLLAVQVTSRLREIFQVELPLQSILFDAPVAGLA-LIATT----------
>tr|K9U384|K9U384_9CYAN Beta-ketoacyl synthase OS=Chroococcidiopsis thermalis PCC 7203 GN=Chro_3663 PE=4 SV=1
------------------KPDITDWFYIPSWKRSLPPEPAG---KCWLVFVDECGLGERIVKRLLEGREAIAVLVGEEFRRISDRVCTINPATRADYQAL
LAELGDRDRQPQVIAHLWNITPSDRPL------EKAQFSYDSLVYLAQALGREKHSVQIQVVSNNLQGVWGS-LLYPEKATILGLCRVIPQEYAQIACRS
IDIVLPEAGK-EKLTEQLIAEF--NSSDIAIAYRETHRWVEAFEPVKLES-TVAKKTRLQQGGVYLLTGGLGGMSLVIAEYLAKTVQPKLVLLGRSVFPH
RDECKIRRLQAIEN----LGAEVLVLSADVANLAQMQDAIASST-ERFGQIQGVFHTAGVYGGGLIQLKTPETADGNLVPKVQGTKVLDLVLKDTHLDFF
ILFSSIASIRGQVGYADYCAANSFLDAFAHYKS-LRDNFTASINWENWQSVGMSIAVQ---LTGKEWQQGMTSSEGL--------------------D--
-----------------------------ALSRILGC-QQALQTQIPP-LQTVADCKFHPRP-------------TLSNTY-----VSPRDEIEQAIADI
WQETLGI--DSIYDDFFELGGDSLVALPMVAQLRDTFQVELPLPTLFNKANVAALA-VIIDN----------
>tr|A0A0C1X6N6|A0A0C1X6N6_9CYAN Uncharacterized protein OS=Hassallia byssoidea VB512170 GN=PI95_57870 PE=4 SV=1
------------------KANIADWFYVPRWKESTPPELAG-QKLCWLVFVDAYGIGDEIAKRLQQGQDAIAVTMGQQFTKLNDRTYAINPQQPDDYNAL
FQALQKQDLNPNAIAHFWSVTPNDTLLNNHQLFEDFQLGFRSLLFLAQAVGENTDPIKLMVVTSNIYDVTGE-RLCPEKATVLGPCKVIPQEYPNLTCCC
IDVVIPYSE-TQQLVDNLLTEF--QTSENIVAYRGHHRWVQTFEKIHLDD-NIAGKTRLKQEGVYLITGGLGGIGLVLAEYLAKTVQAKLILIGRKELPE
RSHRKLQKVLALEE----LGAQVQLKSADVANPEQMQAVIAQAL-KQFGQINGVIHAAGIAGGGVVQLKTPDTATSVLAPKVNGTLVLEEALKNINLDFF
VLCSSITSILGDFGQVDYCAANAFLDAYAQRH--ATTGFTVSINWDAWQEVGMAVETDIKQGREESLKKGILSQEGV--------------------E--
-----------------------------AFGRILRI-KQILQSVIRGKELALLSEPTYPRP-------------NLGNNY-----VAARNEVEQIVAEI
WQQVLGI--EKIHDNFFDLGGNSLISIQVISQMQKELNIQIPLVSLYKSPTVSSLA-ILSGD----------
>tr|S0FN33|S0FN33_9FIRM Polyketide synthase like protein OS=[Clostridium] termitidis CT1112 GN=CTER_0311 PE=4 SV=1
------------------ISNVAEWLYVPSWKSSFVTDKKN-RTGRWLIFVDEYGIGARMTDILANGCEVVTVTAGDEFVQTSRDTFKMNFESSEDYKTL
FSTLKSREELPGEILHLWSMDESRKAG--YTFFEEAQKGFYSMLYLVQALDLDSQPVKIAAVSNSSFNIGGG-TYCPERYTLAELCKIISQEFANISCRF
IDVEVMTSQP-AELAKKLIGEI--VDEKREIAYCRNKRWVRDFERIRAEE-I-GESEPVKEKGVYIITGGTSNMGFEFLKYISKRTKGKIIILEELPFPH
EREQRIRELQKLKH----EGPDIRIVPADFTDQEKIIKLVS-EV-KGLGSINGVIHAAEVEENEIFSETDKKKCEKHFKYKAKALYLLDNALKGSNPDFA
IAVSSLATIMGGLGYAAYASSNAFIDAYANKNA-GDGNHWTSINLDAWKAAGRQDLV--TDFSTSLSRLAMTSEELE--------------------K--
-----------------------------VIGMVLSLSEQILSERISGDEQEKDSGKLHTRP-------------NLQTPY-----AAPENDLEKTIAEV
WAKAFGF--DKVFDNFFDLGGDSLVAIHVVNQIKKLLKREIPAVSLYQTLNIRGMA-LLQQD----------
>tr|A0A0C1XXB7|A0A0C1XXB7_9CYAN Polyketide synthase OS=Hassallia byssoidea VB512170 GN=PI95_00115 PE=4 SV=1
------------------ELNLADWFYIPVWKQSQPLEPAK-QKSCWLVFVDRCDVGSLIVKRLQQGQDVITVTVGEQFTKLGDRAYCINPQQKDDYDAL
FQAVGQRDLTPQKIVHLWGIIASDRTP--IESFETSQLGFYSLLFLAQALGQGTDALQIQVVTNNIHDVTGD-SLCPEKATVLGPCKVIGQEYPNIACRN
IDIVIPKSGTGKKLIEQLIAEF--QPTDLVIAYRGHHRWVQTFEAVRLEE-ASPEKTRLRQKGVYLITGGLGGIGLILAEYLAQTVQPKLILISRSGLPE
KDERKIKKVQALEQ----LGAEVLVKSADVADLEQMERAIALVT-DRFGEIHGVIHAAGIVGEKSQQETYITDCQCQFQPKAHGLFVLEKVLQGKALDFC
LLLSSLASILGGLGYVAYSAANIFMDAFVHKQS-QTNPPWISVNWDVWQLREQEEQ--NITYKTTLAGLAIIPTEGV--------------------K--
-----------------------------AFQRILSKSRQVLQARILR-DIEQNYSPIHPRP-------------NLANDY-----VAPRTHVEQTVANI
WQQLLGI--EQIHDNFFELGGHSLLATQVISQLRKSFPIELPLRSLFSEYSIAELA-LIEQM----------
>tr|G6FSF1|G6FSF1_9CYAN 6-deoxyerythronolide-B synthase OS=Fischerella sp. JSC-11 GN=FJSC11DRAFT_1698 PE=4 SV=1
------------------KPNMADWFYVPAWKRVMLLEPNP-HKSCWLIFVDPCGVGSQIAKRLQAGQDVIIVTIGEEFTKLSDCIYTINPQQQDDYTTL
MQTLRELGKTPQNIAHFWGVTANTTSLGKVEDFCKSQLVFYSLLFLAQQLTHHTTPVQIIAITNNMHEVVGQ-QLQPEKATVLGPCKAIAQEYPHMSCRS
VDIVIPESETFKQLIDQLMAEL--QPSDLVVAYRNGHRWVQTFEPIQLNE-VVPEKTRLREGGIYLIVGDVKGLGLVFAEYLAQTVHAKLILIENSELPA
RNEDQIRRIQALEE----LSGDVLIIKADVVNEEQMQQAMTIAY-ERFGQIHGVFYVPEISGNKSTHEIGKTECEQEFKSKVHGIFVLEKVLQDKKLDFY
LLQSSLSSILGGLGLVAYSAAYLFMDAFVHQKK-QQNSPWFSVNRQAFISDLEKE---YVSLGSTATELFMTPKEVW--------------------E--
-----------------------------AFQRILSMGSQILQARILETVSNSKNSSQHSRP-------------NLQTVY-----VAPRNEIEQTIANI
WQEILGV--SLVNDDFFELGGHSLLAVQVTSRLRETFQVDLPLNSILFEASVAGLA-VIAQQ----------
>tr|A0A0D6KJI3|A0A0D6KJI3_9CYAN Beta-ketoacyl synthase protein OS=Tolypothrix sp. PCC 7601 GN=FDUTEX481_09444 PE=4 SV=1
------------------KPNIADWFYLPTWKRASLPQQTT-QPKCYLVFIDECGLGEKIVTRLLEGGEVITVKVANEYSCQSDRSYTINPEQPQDYKFL
CQELRNLGKTPSHIIHLWSVTPDNLEE-----PQQYELGFYSLVFLAQAIAFYKDNLHIQVISNHLQMVTGS-QLCPEKALIMGPCKVIPQEYVNLTCNS
IDLVLPTTDSWQQLINQLLTEI--QTPEQVIAYRGNHRWVQDFEAIKLDT-SIQGNQRLRQNGVYLITGGLGGVGLVLAEYLAKTVQAKLILVGRSPFPQ
PNEQKIRKLQNLQA----FGAEIMVISADVANYEQMSAVVKKLN-LQFGQINGVIHAAAVFGGGMIQLKTKKIADEALAPKVQGTRVLNEIFQNTRLDFF
VLCSSLSAFVGTSGLVDYIAENSFLDAFAHYHA-AQHSFITSINWDRWNSLGMAVAVH---ITKGELTAGMTAEEGI--------------------E--
-----------------------------AFNKILAHSNQILYSQLL--EEQLAQLAIHPRP-------------NLDNAY-----VPPSNELEITLADI
WQKLLGI--DSIHDNFFELGGDSLFATQLVSQLCKTFQVELSYKGFFNFPTVVELA-TIAKN----------
>tr|A0A0C1Y9I9|A0A0C1Y9I9_9CYAN Uncharacterized protein OS=Hassallia byssoidea VB512170 GN=PI95_00120 PE=4 SV=1
------------------NPEMANWFYIPSWKRSPLP--NR-VLSCTLVFIDECGLGEELVKRLLEDQDAIAVRIGSEFTKLSDRLYTLNPRQRDHYETL
LNQLLAQNKFPKTIVHLWSVTPFDRIE--LETVDKSQTGFYSLLFLAQALGHNTDELQIAVISNNMQEVAGE-LLCPEKATLLGPIRVIPQEYPNINCRS
IDVVIPKSANWQKLIDQLLCEL--HTSDRVIAYRGFHRWVQNFEPVRLDE-AKKETPKLRERGVYLIAGGLGGIGLVLAQHLALKVRAKLILTGRSAFPA
PDECKIRKVQELEE----LGAEVLVINADVTNSEQMQQAIAQAQ-KQFGQLNGVIHAAGVPGGGVIQRKTPEMAESILAPKVKGTLILDSILKDVQLDFF
VLCSARTGILGGFGQVDYVGANAFLDAFAHHKT-HQNGFTVSIDWCAWQEVGMAAEARSDISQTSQLKQELLPLEGI--------------------E--
-----------------------------VFRRILGS-TQVLQSRDIEGKQDNGFKPTQQRP-------------SLINPY-----VAPKNETEQTLADI
WQELLGI--EAIHDNFFELGGDSLLIVQVRSKLREKLNKDISISDSFEY-SINALA-YLTRK----------
>tr|A0A0D6YIA8|A0A0D6YIA8_MASLA Non-ribosomal peptide synthase (Fragment) OS=Mastigocladus laminosus UU774 GN=SP67_11340 PE=4 SV=1
------------------KPNISDWFYIPIWKQSTPLEFVTKKNSRWLVFVDDYGVGDAVAKRLQQSQDIVTVRVAEKFTQLNKYTYTINPQQKNDYDTL
LQELYKQSLIPNAIAHFWSITPNDILLCNAQSFENCQLGFWSLLYLIQAFGQNSDFLKLRVVTNNVHNVIGD-KLCPEKATILGPCKIIPKEYPNVNSCL
IDVVIPSTNITEKLIDYLITEL--QETENIVAYRGHHRWIQSFESIRLDK-NILGKTNLKKGGIYLITGGLGGIGLVLAEHLVKTVQAKLILIGRKGLPE
RSHRKINKILEFTE----LGSEVEVKSADVASYEEMQLVVTEAL-EKFGQINGIIHAAGIAGGGIIQLKTEDIVNSVFTPKIQGTLVLKEILKNINLDFL
VLCSSQSSILSEFGQVDYCAANAFLDVYADYCT-SKSDFTVAINWGSWQEVGMAVETELKLQREQELKKGILSEEGA--------------------E--
-----------------------------AFNRILLS-SHVFQAVILEQELALISQSSHPRP-------------NLANAY-----VAPSNEVEQALADI
WQQFLGI--EKIHDNFFELAGDSILAIQIVAKAN-TLGIKLTSQQMFMHQTIAELVTVIETN----------
>tr|A0A0N7AYN3|A0A0N7AYN3_9DELT Polyketide synthase OS=Myxococcus virescens GN=benC PE=4 SV=1
------------------SKEPAGWLYVPTWRRALPLPS---MRQRWLVLADTQGLGSELTEVLGLGQLVYEVRAGPRNEAISPYTFQLDPSSTDGFKAL
SEWLE---QPVDHLFHLWPFDLGEGVT-----HERRLLGLESVFGLVQALGKWTAPTALRVVAPHAFDVTGG-APIPEAAALAGPCKVISLEYPTWTSQL
VDLEPS-TDRGAQAARWLVREA--ASGDDVVAYRSGVRWLRAYEPLPSTH-LDAAEQGFREHGTYVITGGLGGVGLALAERLARHFRARLVLLGRTGLSA
PHASLAERIRGMEA----AGAEVLVIAADVAEPSSLRTALQQAQ-ERFGSIQGVLHAAAVLRDGPIQLKHMEAMHEVLRPKLDGARTLLTAASDFKMEFV
ILFSSLAAVLGNVGQADYAAANAALDALAHGHV-QDRPRVLSINWDAWLEVGAAHALAARGPLAWLLDEGLTVEEGW--------------------E--
-----------------------------VLQMALRAGPQLLGRLA---EEAHEKRPEVSRE-------------RLTTRH-----VAPRNDTERLIAQA
WTRHLGL--RGVYDRFVDLGGHSLIAIRVLAELKNHFGVDLPLGAIFRAPTIAELAEQALLD----------
>tr|A0A0C1UIN1|A0A0C1UIN1_9CYAN Polyketide synthase OS=Hassallia byssoidea VB512170 GN=PI95_00065 PE=4 SV=1
------------------KSDIADWFYLPFWKQSVPPRLAE-QKSCTLVFIDECGLGSQLVKKLQQGQDAIAIQIGSKFSKLSDRLYTLNPRQSNDYDAL
LNELVAQNKIPKTIVHLWSVTPDDCAE--IECFDSAQLGFYSLLFLTQALGQNTDEFQITVVSNNIQSVTAE-MLCPEKATVLGLVKVIPQEYSNISCRS
IDIALPRQGSWEKLVDYLLDEL--KSSELVIAYRGLNRWVQTFEPVRLSE-ANGKTSRLRNGGVYLITEGLGNIGLILAEYLAQ-MQAKLVLIGHNSFPE
KDERKIRKVQALEE----LGAEVLVLSADVTNFEQMQSAIAFVT-NHFGNIHGIIYAAEIVGDNSQQEIYQTDYQCQFKSRANGLFVLEKVLQGRELDFY
LLISSLSSILGGLGYAAYSAANIFMDSFAHKQN-QTNPPWISVNCDRWQLGE--EQ--NTANRTTLAELFITPEEGI--------------------K--
-----------------------------AFQRILTSDKQVLQARFLLGDIEQTSFIFHPRP-------------NLGNDC-----VAPRTHVEQTLADI
WREILCI--EQIHDDFFELGGHSLLAVHLMAKIKKQLGQNIQLSALFQGATIKHLA-ILHEQ----------
>tr|B2J0Y5|B2J0Y5_NOSP7 Beta-ketoacyl synthase OS=Nostoc punctiforme (strain ATCC 29133 / PCC 73102) GN=Npun_R3425 PE=4 SV=1
------------------KPDIADWFYLPLWKQSAPPELAE-QKFCTLVFTDECGLGSQMVKRLQQGQDAIAIQIGSEFSKVSECLYTLNPRQSNDYDAL
LNELLVQNKIPKTIIHLWSVTPDYHAE--LEWFDSAQLGFYSLLFLTQALGQNTDKFKITVVSNNIQSVTAE-MLCPEKATVLGPVKVIPQEYSNISCRS
IDIALPKPGSWEKLVDYLLDEL--KSSKLVIAYRGLNRWVQTFEPVRLSE-SKGKTSRLRNGGVYLITEGLGNIGPILAESLAQTVQAKLVLIGQKNLPE
KDECKIRKLQALEE----LGAEVLVLSADVTNLEQMQRAIAFVT-EHFGDIHGVIYAVEIVDDKSLQETSQTDYQCHFQSKANGLFVLEKVLQGRQLDFY
LLISSSSSILGGLRSVAYSAANIFMDIFAQKQN-QINPPWISVNCERWELGE--EK--NTASRTTLAELFITPEEGI--------------------K--
-----------------------------AFQRILTSDKQVLQARFL-SDVEQTSFILHPRP-------------NLGNDY-----VAPRTHTEQTLANI
WQEILCI--ESINDDFFELGGHSLLAVHLIAKINNQFGKNIQLSAIFQSPTIKQLA-ILHDR----------
>tr|A0A0F7BMR9|A0A0F7BMR9_MYXFU Polyketide synthase OS=Myxococcus fulvus 124B02 GN=MFUL124B02_23210 PE=4 SV=1
------------------KTDVGDWFYVPSWKRGPRHEPALGDAGHWLLFVDELGVGDALAE--RLGNAVITVRSGTRFHQDGPNRFTIDPRAPADYDAL
LGALQVQGITPSRMVHLWSVTTSEHAT--LEAVERARLGLDSLLLLAKTLGRGTEALRLWVVSNDLHEVHGD--VTPEKALLLAPCKVIPLEYPNIQCTS
VDLVVPTRAGRETPVTQLLEEL--TSSDAIVAYRGPHRWVRTLEPVRLEA-PPEPPTVLRKHGVYLLTGGLGKVGLTLAEYLARSVQAKLVLTQRSPFPD
PRERHILALRELEK----LGAEVLVLRADVADAEQMRTALSRAT-ERFGPIQGVIHSAGVLGDGAIQQKSPEELSRVLAPKVVGTLVLHDLFADAPLDFF
LLFSSLSAIEPGFGQVAYSAANNFLDAFVHGRM-ARAHRVACISWDVWRGEGMAYDALQKMKEEDFDQRGILRHEGV--------------------E--
-----------------------------VFRRVLGS-RHVYLQVL---SELYLEASLHARP-------------KLGNSY-----ERPRGETEESLAPL
WQELLGI--DGATDDFFELGGDSLIGTQLISRVNRSFGVKLSTKSIYTHPTLRGMST--DEA----------
>tr|S9QCF5|S9QCF5_9DELT Malonyl CoA-acyl carrier protein transacylase OS=Cystobacter fuscus DSM 2262 GN=D187_003411 PE=4 SV=1
------------------KADIADWFSVPSWKRSSRRPIEESTPEHWLLFVNGDRERHLLAERLRRGQHVVTVKAGAGFRQDGPNQFTLDAEHPDDYDAL
LRELQAQGLRPSAIVHAWSLSRPEEDE--LASVEEARLGLDSVLHLARSFGLGTDPVRLWMVTNDMQDVLGE--ISPAKALLLAPCKVIPLEYPNIQCFS
VDISLASRGPRGEPLEQLMEEL--GSSDPVVAYRHGHRWVRTTEPVRMEQ-APASASPLKQGGTYLITGGLGKVGLTLADYLARTYQARLVLLQRTPLPA
PGERLLRNVRELEA----RGSEVMVLSADVSHLEQMRAAVARAT-TRFGRIDGVIHSAGVLGDGGIQHKTQPELLRVLAPKVTGTLVLDTIFKDNPPDFL
VLFSSLSSLEPGFGQVAYSAANNFLDAFVSSRA-ARRYHVACINWDVWRGEGMAYDARQKLKEEDFRQRGILPEEGV--------------------E--
-----------------------------VFRRVMGC-RQVYLDML---SQLYIETPGHARP-------------QLGNAY-----EPPEGETEKTLADI
WQELLGI--QGATDNFFDLGGDSLIGTQLLSRVRKSFGVKLSTKSIYGHPTIRSLSS--DEA----------
>tr|B2J0Z0|B2J0Z0_NOSP7 Beta-ketoacyl synthase OS=Nostoc punctiforme (strain ATCC 29133 / PCC 73102) GN=Npun_R3430 PE=4 SV=1
------------------KPDIADWFYIPSWKRTMPPQPIT-QPGCWLVFVDEFGLGERLVKQLLENQDVITVKVGEQFQQSSEYTYTINPEKEDDYNTL
LKGLRTLGKIPRRIVHLWSVTSNSYTN------SAIELGWSSLLFLGQAMSDKTDAVEIAIVSNNLQEVTGS-MLCPEKALVLGACKVMPLEYANINCRS
IDVVIPESESGEQLIKALIAEL--YTSDQVIAYRGRNRWVQDFEPVQLHG-TVAGN-LLREQGVYLITGGLGGVGLLLAEYLAQTVQAKLILLGRSAFPD
QDKQKIQKLQAMKT----LGAEVMVVSTDVTNLEQMSAVLKKAN-QRFGEIHGVIHAAAVYGGGMMQLATKETVASAIAPKVQGTRVLETLFQESKLDFF
VLCSSLSSFAGTSGMVDYTAANAFLDSFAQYSA-AKYGFIKSINWDRWNNVGMAVPVH---ITGKELIAGMTAFEGI--------------------E--
-----------------------------AFKRILCSSTQVFLSLIL--EEKLAQLSTHPRP-------------NLANTY-----VAPNNEIERNLADI
WQQILGI--EKIHDNFFELGGDSLFATQLVSQLCKVFQIELSYKGFFNGPTVADLA-VIVQK----------
>tr|B9ZUK0|B9ZUK0_CHOCO Polyketide synthase OS=Chondromyces crocatus GN=cndE PE=4 SV=1
------------------KRPLDDWFYVPSWKRSLLPTR---STNSVLIFA-DARLAPPLAARLALDGKVTLVSPGAEYSRTESGHYTIDPRSSAQHHSL
FSDLRARNALPTAIVHLWMTDPEAVSP--AAPSESALLGFYSPLFIAQALALATAPVHLMLVSTHLQAVRGD-AVRPERAVLLGPCKVIPQEHRTVRCTS
VDLDIDAHAAGTTQLDQLVAEL--DVRDAIVAYRGPHRWVQTLDPVQLSP-STGTPSRLRQQGTYLITGGMGGVGLAIATYLARTVKARLALVGRSPLPA
REQQKLQAIREIEA----LGGEVLPLIADVTHAEQVKSALEQSI-ARFGALHGIVHAAGDFGGNLIVRKSPEETTRIIAPKVHGLLHLDHALAGRQLDLF
ISCSSLTGVVGGPGQVDYVAANAFLDAFAHSRS-GRPTATLSLNWDDWKDVGAAFKIR-AAWREEHYQTAMTTAEGI--------------------E--
-----------------------------VLKRALAH-DQVLGPRMAEDLEQFGQRTARPRP-------------ALGTTY-----VAPRTPMERRLTEI
WQDLLGV--DPIHDDFADLGGHSLIATQLVSRLREAYRLDIPLRRVFESPTISDLAQSLLVA----------
>tr|A0A0F7C1V4|A0A0F7C1V4_BRELA Uncharacterized protein OS=Brevibacillus laterosporus GN=EX87_22655 PE=4 SV=1
--------------------NMADWFYVPSWERVPLSGGYGAME-SVLIFADDTSLSKCLLEKLKQISTIVVVYKGATYRKIDDRSFVIHPSETNHYDQL
LREMQELGFTATKVLHLWSVNEDKYELDTTRVEQAIDFGFYSLVFFVQALGRQMNPLDILVVTNNTQEVTGEEELQPEKATVLGFVKIAPLEYSNVNCRH
IDILSIDPYKREKVAQQLLAELETVSEDKVVAYRNNYRWVQIMKKS--YWEARKSTPRLKQHGVYLITGGMGGMGFAIAKDFAQNYQAKLILIGRSEFPP
RMNNSIQKIREILQLE-TDGAEVMVVRADVSNQLQMADVIQC-ANERFGGINGVVHAAGIADYAGLINRTRETVETILKPKIHGTLALDYLLREQKDFVL
CSSIGNVSYHRKVGQVAYNVANEFLDAYAFYKTARDGVHTVSINWPDWQEVGMSIESAWAKALHTNLQDGLNQSEGVEVFKRALHSASPQVVV----SSE
DLIKKI--------AEG-------------------SAH--FQAVEQGQFSREINQ---RPKLS-------------------TNYVAPKSEIEGKLANI
WQKMFGIEQVGIHDNFFDLGASSLDLIQVNRKVKEMLNLDISVVTMYEYPTIASLAAYLIQE----------
>tr|A0A068J4Q3|A0A068J4Q3_9BACT Putative NRPS/PKS hybrid synthase module E2C OS=uncultured bacterium PE=4 SV=1
--------------------DLADWFHVPSWERTVFPSDMGGWKENWLIIANDPELVAGFKATLEGRATVDVALFGTAYVHRDDGVYEIGAAELDDYVDL
IGSLKLGSAGALNVLHLGGLCRRA-VLVRGLVGPSQDHGFYSLVNLAKAIGEQDIPIRIGFVTSQVHEVTGEETLNPVMATALGACGVMPKEYPHVKSFS
VDLPAIISVGFDIWVTRLLGEFHSPEPGAVVAYRGQYRWKRTYVTQKDTGEGNHRLPGLRDRGVYLITGGTGGIGLVIAKFLAKTCRARLVLLKQSAFPA
KSKDAERVLQALLEIE-SLGGEVDVLACDVSDEDGMVNAVQE-VLSRHGAIHGVIHSAGLIG-VGLIANDRSAAEQIFSPKVDGSLVLYRALKDVSDVVF
NSSITSV--TTPYGHVDYSAAHAFLDTFAAYWSDHSEVRVLTINWPGWREVGMLANLK--PGLEKWLRRAIRTEDGLEAFRRALASGLPHLVV----SPE
GLEDAE--------PSA-------------------EL---LTRSPGGART----P---VEESR-------------------SAVDGPRDEIEQAVHQI
WCNVFGISPLGIHDNFADLGGHSLLAMQIVSRIRRTYPITYTLRRFFEYPTIAGTSSAIRAQ----------
>tr|A0A0F9MHW3|A0A0F9MHW3_9ZZZZ Uncharacterized protein (Fragment) OS=marine sediment metagenome GN=LCGC14_1072140 PE=4 SV=1
--------------------AVENWFYQSNWQLSEPLINHVGKSKDVVYLCRNRSFLETLLATSG-------VNKHNVFADISTTVLSFNPLHSQLCNSF
AEKLNKSNKMTL----V--YCDSFLGADEHEQQVQNNNDFIALINIVAACVQQWVEIDLYVATEQVFRVDGNEQINTLSALLRGVVKVAPQEFSNVSCYH
VDFASTGEKSSQRVASQLFSETQNHSANKEVAFRGNARWIRELSKFDR--IVDASERNLRSGAHIFITGGLGNIGMTLAKWLAEFGVAKVTLLSRKGKD-
----SI---AAMP--K-LEHGELHIVQGDVSNFESLQSGLHD-AVARFGEIHTVIHAAGNIHDSALVDTDEVVCEQQFSSKVTGLLNLDCALESYNQCVL
MSSVAVE--LGGLGFTAYTAANAYMDAFCNKKQNEGDTAWISINWDGWAFGADAARSP-----------SLTAQEGVESMFWVLRMHSGVVIN----SKT
NLHERT--------KKWIE---------------FEQDN--SAV---------LYD---RPELS-------------------KAYCAPQSETQKALVQL
WQEALGISNLGINDNFFELGGDSLLATRLVGNVCKRFNVTDAVKDFFAESTIISAAQRIDSH----------
>tr|H2JD26|H2JD26_9CLOT Amino acid adenylation enzyme/thioester reductase family protein OS=Clostridium sp. BNL1100 GN=Clo1100_0888 PE=4 SV=1
--------------------DISDWFYLPLWKQSAPSILNSDNNKTWLVFTNNISFNSKLLEALKEKEDVIKVTKGSDFNKVDDSEYTINVNREEDYNNL
LNELQKNGELPSNILFLWGIDEDERTLELDSINEKLDTGFFSLVYILKALLKQSDKVRIVVATNNLHNINGAEKVNPAKSAVLGPCKVIPQEAPFIECKN
IDICIPDEVTK-KLIKKVLADIFDEKTETVVAYRNCIRYTPSYSPMRLTQDANRENSSFKNNGVYLITGGLGNIGLKLAEYLAEKYSAKLILTGKSEFPR
RDDEQIMKIQSLLYLE-KQGAKILTYTCDVADQESMETIVDE-AERHFGHIDGVIHAAATMRDSLTVQLNKEDCIEQFNPKIHGLLTLYKVFKDREDLTV
TSSTSAL--LGGLGFCAYSAANIFMDSFVNEFNRVASKEWLTVNWEGWRFNSDKTQFSFSTSL---DELLMEPEQGVEAFERIMNPGIGQVII----SSG
DLNKRV--------DKWIK---------------LDSIN--STESKD----SGNKQ---RPNLK-------------------NSYVMPANKLEETIAKV
FADFFGYDEIGIDDNFFDLGASSLDMIQITNNLRRQLNTNIPILKLFTFSTIRTLAANLQNS----------
>tr|A0A059VU53|A0A059VU53_STRA9 Beta-ketoacyl synthase OS=Streptomyces albulus GN=DC74_397 PE=4 SV=1
--------------------PLDQWFSTPVWRQAIGTLDAAEPIAPVLLFADAGGTAARLTR--HAFGEVLTVTAGTDYAR-DGDTWTIRPDSEEDHARL
VGDLLAEERLPDRVVHAWSTAPLPAERGKERFEQAQRHGVYSLIALVKAVSAHGHPLQLDLISAGAYALSPAEPEAAELAPLAVAARVIGQEHGNIGSRH
FDLPGTDDRSR-----TLAAELARRRPEVATTLRGATRWIADLEPVR-ADWTAKATSRLRDGGVYLITGGLGEIGSTLAHWLRRECPARLALLTRDPLPP
REDDPTLRMTRLRALA-AEGPEPLLVHADVADEDALRTAVEQ-VTGHFGALDGVVHAAGLPSEQWAIAASVEQCQWHFAPKAHGQIALEKVLADHPDCLL
LSSLAGV--LGGLRLLGYGAANHFMDVAAERANRLDRTVWISAAWDVWQHHQDEKRAIIGRSM---DDKAIQPEEGLEAVRRLLTRDVSHVAV----STW
DVAHRL--------DQWVR---------------DERIA--RPT-TGGT-----AA---AAADG-------------------AGPDGGADDLTEQVARL
VRGALGREDMPLDGDIFEFGGDSLLIVRLLSDVRDQFSAEVPLADVLGEPTPRALARFVQER----------
>tr|W4LVP7|W4LVP7_9DELT Uncharacterized protein OS=Candidatus Entotheonella sp. TSY1 GN=ETSY1_05325 PE=4 SV=1
--------------------DFSDWFYVEDWQSKGLEEV--GSMSNWLILTQPEQLR-----WLAEQASVVVVQPGAGYARREAGDLTINPDEPSDYDRL
FAELLAGGMFPARIVHAWKWGRKEEVTVLEHLDAEQKLGLYSLQYLIQALGRLRHPVRVDVISDQVFAVMANESVYPEHATLIGACKVIPLEYPDVHCRL
LDIPVGEA--------SLQQELGADTQDPLVAYRDGKRFIPGVKPRP-LDEACENLAHLKSGGTYLITGGLGGIGHAVARFLARTVQANLVLVGRRPLT-
---EQDQRMSRLRELE-SLGARVLYVAADVAELASMRQVIAQ-AVAEFGPIDGVVHSAGVADSAGAILRTREMTEEMLRSKVRGTLVLEAVLAGQPDWAL
FSSISNVLYHNRYGQLSYVAGNSFLEAFAARLR-HRGQFAVAIAWDEWQDVGMAAEVAFAASFGKQPLDSFSPQDGERAFHRALASDVATVMI----STR
DLRLRI--------RLD-------------------VHA--KSPFEA-AREMAVNA---GVASP-------------------SNQDMASLSGKQQIAQM
WQRILGVADIGHDDNYFALGGDSLSAVRFLAEVNREFGEQVPFAAMVEFPTPAMFAEYLELD----------
>tr|A9AV11|A9AV11_HERA2 Beta-ketoacyl synthase OS=Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785) GN=Haur_3967 PE=4 SV=1
--------------------DAGDWYAVPSWKRAVAHDELAGDQGSWLVLADGEGLAAGLTAWLERGQTVITVTPGAAFAQHSATAYTVRAGSREDFTAL
LQTLERHGQMPSRIVHAWLATPKVGAAQLVGLAESLDLGFYSLLALAQALGEQDIWCEINVLTSEMHDINGREELNVAAAAVIGPCKIIPVEYPNLTARS
IDILLPASAERATLVAQIGAELATPPTGDLVAFRGAHRWVQMMEPVALPTAPASH-PRLRTGGVYLLTGGLGGIALGLARDLAATLQAKLVLVNRSSLPD
LEAGVGRRILDLEA----LGAEVLVIQADVTDAVAMARAVAEAQARFG-TIHGVLHTAGVPGVGLMQLKDAATAAAELAPKVQGTLALTRALAGVPDFLV
-LFSSVTSATGGPGQVAYCAANAFLDAYARKHATDHGRSWGEWLWDAWSDSAEDQ-LRFRAYRRTFGITFDEGAEALRRILACRIS-----HL--FVTTE
DVVAMFE--------DSK--GSALQR-------------AA---RQEDAAQRYPRPE----------VST--------------SFVEPQSELEQQVSAI
WSEVLGIAPIGVNDNFFDLGGNSLIGIQIVTRLRRTFQVALPLTILFDAPTVEEMSIAIEMMLI--------
>tr|A9AV07|A9AV07_HERA2 Beta-ketoacyl synthase OS=Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785) GN=Haur_3963 PE=4 SV=1
--------------------DVGDWFAAASWKRGLPFDAEAKESRCWLVFQDACGVGAGLAAWLERGQTVITVTPSAAFTQLGDSHYSVRPAERDDCTAL
LQALERQGQTPSRIVHAWLVAPADHASDLVVLDQTLQMGFYSLLALTQALGDQGVGCQIDIMTSDMQEVTGHEPLQIAKATVIGLSKIIPQEYPNLTARS
IDLSLLAGLLSQQLIAEIATELVHPPTGDQIAFRGIHRWVQVFEPLNLPAAPASH-PRLRMGGVYLLTGGLGGIALGLARDLAATLRAKLVLVNRSSLPD
LEAGVGRRILDLEA----LGAEVLVIQADVTDAVAMAQAVNQAQACFG-TIHGVLHTAGVPGVGLMQLKDAATAAAELAPKVQGTLALTRALAGVPDFLV
-LFSSVTSATGGPGQVAYCAANAFLDAYARKHVTDHGQSWGEWRWDAWSEPEEIQ-AKFRAYRSTFGITFEEGAETLRRLLARRFP-----HL--FVTSD
DLLAMVE--------GSK--QIFASGGG----------LVGNQ-EQESVRSTYPRPE----------VGT--------------SFVEPQSDLEHQIAGL
WSELLGIAPIGANDNFFDLGGNSLLGISLFGRMRKTLKLKLPAHVLYEAPTVKAQADYISQEQA--------
>tr|A0A066TQ73|A0A066TQ73_9PSEU Uncharacterized protein OS=Amycolatopsis rifamycinica GN=DV20_37350 PE=4 SV=1
--------------------PEEQWLNLPTWRQTSAAPAA-PRPASWLVFAR-PGLAEDVLGGIRTGDPVTVVRPGAGYRPGP--DATVRPGDIGDLLAL
LRDLKRSGTRLDRVVHLWNLDDGD----------ALSLGLHTLVALARAAGELGLW-TLDLAATGTQRVLHDGELRPDAATLTGPNLVIPMEYPGVQTRL
IDVDAAAGV-------GVVAELHRPAPGRTVALRGSRRWLPGYEVLAPQPIEQAR-EVLREHGVYLITGGLGGIGLAMAERLARDSHAKLVLFGRRGLPP
AAETIRDRVLAIEA----LGGEVAVVEGDVAEEADVRRAVAVAVERFG-ALHGILHTAGVPGTGLMQFKEPGDADQVLAPKLPGSRALSAATEGLDDFVA
-LFSSITSVTGGPGQVDYCAGNAWLDAYAAGH---GGRSWGEWTWNAWDDEEDIQ-TYFREHRAKFGIDFEQGWRTLLRALASGEP-----HV--VVSTQ
DLPAVTA--------VAA--RFSVDA-------------VTSA-AHGKTADRHPRPE----------LVT--------------PFQEPEGDAERAVAEA
WCDALRLDRVGASDNFFELGGTSLLGISLLATLRTAYPDELPPHIIHEAPTVAALAKIAAGGPE--------
>tr|C2XEJ3|C2XEJ3_BACCE Polyketide synthase type I OS=Bacillus cereus F65185 GN=bcere0025_31530 PE=4 SV=1
--------------------NISEWFYTPQWKSSTLFEPNHDVNETWIVFVDQEGLGNELVKDLNKGQRVVTVEPGFAFNKENNDRFIINPEERTDYVKL
LDEVQEIYGLPTRIIHMWGITNEERQASIEYVNCKQNLGFYSMFYLTQALGDKNISISIRIITNGVQQVIGDEELIPEKSTVLGTSLVVPQEYSYLSCSS
VDVVLPLNKEKNRLINQLVEECLSNTNDKMIAYRGNKRFVQTYEPLQLEQPAKEK-LPLRKNGVYLITGGLGGIGTILAKHLAQTLQANLVLLTRTGLPN
LKEMYSDRILEIEE----TGSKVYVLAADVTDQSQLYEAIHKAEQKFG-KINGVIHGAGILGGKTFNLIQKEDCEEQFSAKIYGLLNLEECLRNKDDFCV
-LMSSISAVLGGLGYVSYAASNIYMDVFAQYINRYSKLPWISVNWSDWKYWEDEEDMQIGASVHELSMTPEEGVQAFNIALWKQGE-----VL--IHSPG
ELQARID--------QWV--LLNSFN-------------DEKE-EELDSTLYHSRPQ----------LLT--------------EYVAPRNEVEEKLSKI
WRNIFKVSEVGVHDDLLELGGDSLKAITIVSKIHKEFNVEVPIKELFTLSNIEKLANYISRADK--------
>tr|A9AV10|A9AV10_HERA2 Beta-ketoacyl synthase OS=Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785) GN=Haur_3966 PE=4 SV=1
--------------------DAGDWYAVPSWKRAVAHNIV-TEPGCWLVLVDGEGLATRLTAWLDRGQTVIAVTPGAAFTQHSATAYTVRPASREDFTAL
LQTLERQGQTPSRVVHAWLATAGDPAADEAGFDHTLQHGFYSLLALAQALGDQGVWCEINAVTVAMQEVTGQEDLRIAAATVIGPCKIIPVEYPNLTARS
IDILLPASAERATLVAQLGAELATPPTGDQVAFRGAHRWVQMMEPVALPAVPASH-PRLRTGGVYLLTGGLGGIALGLARDLAATLRAKLVLVNRSGLPD
LEAGMGRRILDLEA----LGAEVLVIQADVTDAVAMARAVAEAQARFG-TIHGVLHTAGVPGVGLMQLKDAATAAAELAPKVQGTLALTRALAGVPDFLV
-LFSSVTSATGGPGQVAYCAANAFLDAYARKHATDHGQSWGEWLWDAWSEAPEVQ-AEFRAYRKNFGITFAEGAEALRRILACQIP-----HL--FVTTE
DLLNMFE--------GSK--RSAART-------------QAEP-TEQQARTRYPRPE----------VG---------------SFVEPQGELEQSIARV
WADVLAIEAIGANDNFFDLGGNSLLGIGLINQLRRNLKLKLPAHVLYEAPTVATLADYINQS----------
>tr|I0F1D5|I0F1D5_9BACI Polyketide synthase subunit OS=Bacillus sp. JS GN=MY9_0752 PE=4 SV=1
--------------------PMDQWFYLPSWERKIKSADSKAESGKTLVFHEGTAFGDRLVQAMRQGHETVIVTRDRQFKKINSGLYVINPSDGTHYERL
FSSLASDGLLPNCVMHLWSVSEQEE--SYKTFSTYSENGYYSLIFTAQAASNQKQECNMFVLTSGIHEVTGEEQINPEKSTILGPLKVIPQEYNHLKCWN
IDIPPLPDLTEEELIDQIMMETDAAGEDQIISYRNRRRWVQMYQPVQLNKASGLP-NMIRPKGVYLITGGLGGIGFVLSKLLAQEGNVRLILTGRSELPQ
CEDPTSVKIKELER----LGAKVTALQADAGSLSDMQAVMRKIHTEFG-ELNGVFHAAGLPGSSSFRAITIEGGEDQFQSKVRGLKVLESLLENENDFCF
-LFSSISALLGGLGFSAYSAANIYMDAFAARVNQRSKTPWVCVNWDAWNFWGQLE-STIGESIAELAILPEEGAALFQYVLDINNR-----HL--LVSTG
DLGHRMK--------QWI--SMNADS-------------IAKE-E-KKAGALHTRPE----------LNN--------------PYVAPRNKTEQVICGI
WQDFMGLEQVGIHDNFFDLGASSLDIVQVTNRLNKELGTNEAVVTLFTYPSVAALAQFISPDQE--------
>tr|H3SBB7|H3SBB7_9BACL Polyketide synthase subunit OS=Paenibacillus dendritiformis C454 GN=PDENDC454_04014 PE=4 SV=1
--------------------NMADWFYYPSWERTVLQEVPDDGRHDWLIFADGCGLADELAALAQEGHRAVKVEAGTAFAKRDPDTFTLAPAVAEQYALL
LEELRAREFTPDRVVHLWNVSPADEKLPDESEGRQQELGYYSLIFLAQALRRQKEDVRIAVVSTDMQEVTGLERLSPGKMTLLGPSLVIQQEYSGMTCVS
IDIDAPEGGHHRRTAERIAAELSVPASDRLIAYRGPYRWVQQYKPLALRQADPPA-APFRERGVYLITGGLGGIGMLTAEYLARHYRARLILTGRSSFPA
LAEPSSRKIQQLEA----LGAEVTYIQADLSDEAQMSRVFESIDAAYG-GVNGVVQAAGLPGTESFRAIEGGQTDEQFRAKVQGLQTLSKLLAGREDVCI
-LFSSIASVLGGLGFSSYSAANLYMDAFARRQNRAGGTKWLCVNWDAWEFWEEHR-STIGESLVELAILPAEAPDLFRYVYRCGSN-----QI--IVSTG
DLDMRID--------QWI--RHAG---------------KKKE-EPAGSGTTFGRPN----------LTN--------------PYVAPRNRIEKTIADV
WKQFFRMDEVGIHDNFFDLGASSLDMIQLTGKLNEALGESIAVVDLFTYPSIHALAQRLTRNGQ--------
>tr|A0A0M0VXU2|A0A0M0VXU2_9BACI Polyketide synthase subunit OS=Bacillus sp. FJAT-18019 GN=AMS62_15360 PE=4 SV=1
--------------------DMADWFYYPSWERALLEEQPHHNSHNWLVFKDDCGIADELAASINMGERTVMVKAGNAFCAHENGTFTLSPSSAEHYVRL
LEELQKRDFVPDRVAHLWNVSSSGDEEEEAVERRQQEEGYYSLIYLAQALRKHKEDIRIAVVSSGMQEVTGMERLSPGKMTLLGPCMVIQQEYSGITCVS
IDIDVQEERQKRRIADNVILEISSPPSDRLIAYRGSYRWVQNFKPVELRQAEKPA-APFRQQGVYLITGGLGGIGMLTAEFLARNYGARLILTGRSSFPD
LAEPLSRKILQLEE----LGAEVTYMQADLSNEEQMRDVFKFIDREYG-RLHGVVQAAGLPGGESFRAIEGDQSDEQFRAKVQGLQTLGRLIADREEICI
-LFSSIASILGGLGFSAYSAANLYMDAFARKQNRAGGTKWLCVNWDAWEFWEEHR-STIGESLVELAITPAETPDLFRYVYPCGSN-----QI--IVSTG
DLQTRID--------QWI--RHAG---------------KKED-SHAAGGASFSRPD----------LTT--------------PYAAPRNRVEKTIAEV
WKQFFRIDEVGIHDNFFDLGASSLDMIQVTAKLNEALDESIAVVDMFTYPSIHALAQRLTHSEE--------
>tr|A9AV08|A9AV08_HERA2 Beta-ketoacyl synthase OS=Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785) GN=Haur_3964 PE=4 SV=1
--------------------DLETWSAIGSWKRSGPAASARNEPHYWLMLVDDDGLAVDVTAWLQRGQTVIAVTPGAAFAQHSATAYTVRPASREDFTAL
LQTLERQGQTPSRVVHAWLATAGDPAADEAGLDHALDHGFYSLLALAQALGDQGVWCEITVITAAMQEVTGQEDLRIAAATVIGPCKIIPQESPTLTARS
IDILLPASAERATLVAQIGAELATPPTGDLVAFRGVHRWVQVFEPLPLPAAPASH-PRLRMGGVYLLTGGLGGIALGLARDLAATLQAKLVLVNRSGLPD
LEVGVGRRILDLEA----LGAEVLVIQADVTDAVAMARAVAEAQARFG-TIHGVLHTAGVPGVGLMQLKDAATAAAELAPKVQGTLALTRALAGVPDFLV
-LFSSVTSATGGPGQVAYCAANAFLDAYARKHATDHGQSWGEWLWDAWSEPEEVQ-ARFRAYRSGFGITFAEGADILRRILAEPLT-----HV--FVTSE
DLLPMAE--------RSR--RSSA-ARE----------LAALR-EQQSARPTYPRPE----------VG---------------SFAEPQNDLERQIAGI
WSEVLGIAPIGANDNFFDLGGNSLLGLELFSRMRKALKAKLPAYVLYEAPTVATQAVYLAPTPQ--------
>tr|A0A0H0SSK8|A0A0H0SSK8_9BACL Polyketide synthase OS=Brevibacillus formosus GN=AA984_04320 PE=4 SV=1
--------------------LMGTTMLTPVWNAVLVEKGE------------------------ATSEKVVIVCAEEKLQRHYPQASVIQLQPIDSIEVI
ASKLEEQGMIN---HILWVAPDSPVDSVKESLMNEQERGVIHVFRLIKALLALGYDLGWTIITVQAQAINKKDKVHPTHASIHGLIGSMAKEYPNWKVRL
VDLEA---AELRDVF-----ALPADAHGNAWAYRRHAWYRQQLMPVQSPSIN--Q-TVYRQHGVYVVIGGAGGIGQAWSEYMIGTYQAQIIWIGRRKKDE
---SIQNKINQLAS----LGPAPHYIEADATDRESLQSAYEEIMKQYG-KINGVIHSAIVLLDRSLANMDETTFRAGLVPKVEVSVRISQVFGQEPDFVL
-FFSSINSFTKSPGQSNYASGCTFKDAFAHQLAKEWTCAVKVMNWGYWGSQERME------QIGIGSIEPSEGMEALEALL-GPMN-----QV--ALMKT
TKPLEME--------GINTSSMASIQNK----------LKVKE-MP---KAAYFASE----------ADT--------------GADSLFDDVQATIIQL
ASQILKVEEIDADIELKEYGFDPVKLTEFSAKINQKYKLELTPAVMMDYPTLKHMTEFLVNTTL--------
>tr|A0A0F6Y0Y3|A0A0F6Y0Y3_BRELA Beta-ketoacyl synthase OS=Brevibacillus laterosporus GN=EX87_22650 PE=4 SV=1
--------------------NISEWFYTPQWSSVPLQKAKSLAEQRWLIFTDEGGLGTKVAAGLTVAKSVVVVKVGETFEKLAENCYQLNLKEESHYSML
LSELSEDDKLPTRIAHFLGVTSIEGNAALRLSD-FQERGFYSLFHLMKSLVGKQIQIDIKIISNNVHEILGDEPLIPEKATVLSPAIVAPQEYSYLNCSH
IDIVFPSMSKEKKLVEQLMAECCSPSTDKLVAYRGKNRWVQGYVPQSLDNGEETP-SPLREKGVYLITGGLGGIGLILAEYLVKTVRAKLILTGRSGLLG
IEEPISQKMQELEK----MGGEVLLFACDVADKDQMQAVITQAEQIHG-SLNGVIHGAGVLGGNTFNLMKKTDCEDQFKSKMYGLRVLSEVLREKQDFCL
-LMSSIASVLGGLGFTAYSAANLYMDYFVQKYNRDALVPWISVNWSDWKYWDETEDKTVGGSIWELSMLPEEGVQVFQRILSG-ET-----WV--ANSPG
DLQVRIN--------QWV--HLQSLR-------------SEEE-NES-EVVLHARPM----------LMS--------------SYVEPRTELEKELVEI
WQKIFRVNQIGIEDDFFELGGDSLKGITLVSRIHKELHVEIPVAQLFDTPTIETLCTYIQNAEK--------
>tr|Q09D72|Q09D72_STIAD Linear gramicidin synthetase subunit D OS=Stigmatella aurantiaca (strain DW4/3-1) GN=STAUR_0025 PE=4 SV=1
-GGRFAQTLRALDLHQGNANTVPAWFFRKVWRPKEASPRAPVPGGACLLFLKGEGLGPLLREALLREGRCITVTPGPAFARTGPDAFCLAPADAEAYPRL
LATLAEEGVRLAQVLHLWTADAQG----APPPAEVQREGVLSLLLLTQALTRQRTPLRLQVVSHHAQSTSPGEDVEPDKALMLGLIQTIPQEVPWLDARH
LDLPRG---APEEEVPWVLRELEALPREREVAWRRGQRLVPRLEQVPPSALG-PRSPPFVSGGVYLLSGGLGSLAVELSRRLLKQFRARLLLLGRTPLEA
PHAGRREAWKELVALAAKQGGAVHYEAVDAGDAGALGDAVSRAEARWARPLDGILHLAGVLEERILAEETVEHFLSVLRPKVEGTRALEQLLGTRPGAFF
VGFSSVNASFGGFSVAAYSAANRFLEHFVEARRGAQGTRHFCFSWSQWEVTGLVLSETEERLANARGYQTLSLSRGWNSLLVALGHASGNLLVGLDARSL
PIRVRMGVLARAVQPQAFVTGSPGQDTGAG------AALPEVRDGL-GLRTPVLQRVERIPRTASGAVDTGALLALENGLPRAQERLALQGEAERKVAAI
WKEALGVEEVGALDNFFELGGHSLLLSQVRGRLAQDFGRPLPVLELFRYPTVRTLAAYLSG-----------
>tr|A0A078L2Z9|A0A078L2Z9_9GAMM Polyketide synthase PksJ OS=Legionella massiliensis GN=pksJ PE=4 SV=1
-------------------------------------------PKTWFIFANEQQPYLE-QCIRDAGHFLYTIKSGKEFKQLTDSSFVIDPTQKSHYGKL
LGLVKIRGE-QGVILHAWLLENGNSK-------TTLFDGPFSILYLSQLLSE--LHPKIQFNLTLASNLFGNEQIIPIKAAVLGPCKVIPLEQENLFCKV
IDLDQKEKI-TAKLANALFHDMTRDCAKDEIAYRAENRWIRVLDPCSDYLES-LNSPRIKTKGVYLITGGLGGIGLSLAQHLATNYQANIILLSPNLLSL
EQDEKLKLLADIRSKAE----SLTIEQASVENKSRIRGIVKSILEKFG-RLDGVIHAAGLAGGGVAQLKTLDEYNRVLEPKLQGTETILKALYDVPLDFI
VFLSSTTSILG--YPGDYCSANRVLDAFANTNPFKHPVFCVSMNWQAWRDVGMAAESETKSLNESNSYTAREAVILFEKIVNSDLN--QVIISKSDPNKL
---------------HISI--NS------------------LAKDP--------------------LPSIES--------------SVDDNGITSLVLQI
WRDILGINDIGLDDDFYELGGHSLLAITLLAKIKKQFNTKIPTAALFEAKTIRSLSELIQTY----------
>tr|S9U975|S9U975_PAEAL Amino acid adenylation protein OS=Paenibacillus alvei A6-6i-x GN=PAAL66ix_19044 PE=4 SV=1
---------------------------------------------VLLIVGEHWQEQLA-NKFRGEGMDVVQMYFSPQYRQLERQVYEVNINKEDQIADV
LKQLRDSGQIVNTCIHISSSQPLQDR-------MVVDGILAPAWYLTRQLAL--HTAATPARFHITRNASGDAIVDPLQSFIVSLNRSANHEYPLLESRC
IDLEASEWA-KDVSLQHIYNEVCWHDETKEVAYRHATRYVRYLKESV--PSK-TKRELFRNDGVYLVTGGTGGIATEICRAIASKYRATFVLLGRTREEN
M---SQRQLADIRALAELG-ADVQYFAVNIAERNELESTVERISTQYG-NVDGVIHAAGVLGKRVLLEASMEDYQDVYEAKVYGTVLLDMLLREHMVDFF
MTFSSVDAILSEKNLGHYTSANHFMDQYALQQRQLGRQ-FISIQWGGWQFTGMGSKNEELSHIHELGYDRKQGIGAFWTITGARSS--HLMVTGLDEQDL
---------------QALDKYFK------------------LEPDLRKRM------------NASSAKPSIA--------------DISLESIESTVARV
WTEMLEMEQPDVNENYFSIGGDSILGIDITVQLSQIYQLQLDANTLFRYDTIRSLSRFIHEQ----------
>tr|W2E5S9|W2E5S9_9BACL Putative non-ribosomal peptide ligase/ polyketide synthase hybrid OS=Paenibacillus larvae subsp. larvae DSM 25719 GN=ERIC1_1c04
-------------------------------------------VTCWLIFADGIGEYMA-ERLKKDHRHVITVDIGTGFRKISEQEYVMDPGIPANYQAL
FSELQASGRFPDRIIHLWSISSSSTS-------QAQDAGFYSCMYIAQSIGL--LKVTKQIRAVITSNMTGEEALNPEQATVLGFVKICPLEYANISCQS
IDITTNIET-PD-LIERILGDISAPQPDLMIAYRGSYRWTPLYKQVQLDNNG-LSAERLKENGVYLITGGMGGIGFAMAQHLSKRIRANYVLLGRSPFPD
RQESTIKKIRGIQGMEENG-SEVMIVSADLSCSEQMEEAIARIRARFG-KINGVIHAAGIADYEGIQNRTKEMSEKILAPKVKGTLILDSLLEDEELDFL
VLFSSNGNMSYHYKFGSYNAANEFLDAYANYKRASSKAYTVSINWCDWKDVGMSVEAAEKERLKTAAITISEGMDVINYVLSSLLS--RVIVSPVDLQAE
---------------IAFEEFLK------------------MVKDQETYSL----------KEQGAETDRHM--------------PAKTGEIQNTLISI
WTDLLGDEEIGIHDNVFDLGANSLDMIQANSRLKAIMKQDIPIVTMYTYPTIHTLAEHLTRG----------
>tr|V3T1K6|V3T1K6_9ENTR Beta-ketoacyl-acyl-carrier-protein synthase I, 6-deoxyerythronolide-B synthase OS=Serratia sp. ATCC 39006 GN=Ser39006_03352 PE=
---------------------EQTHSYTPMWLADGAVTA-CEGEGCCLLLCQQQGLQSNLQRLWASGMQSLLVTHGEKAGQDSDDSFTACFSDVQQLTAC
FRRLKQASRLPRTVVHYGSGENSEDAQKAL----------SGLVNIIRAYKAGDAELKLLIITQYLYSDKGGS-ESACQAVKTGFARVINQEYRDIHCQL
VDFESDKV---ADIAAGLLFELANPSGQVIVLYREAQRWLAHWQSSRLTGQQ---SPGFRQGGVYLITGGLGNIGFALALRLIHKFQAKIVIITRSDGLS
--DYQQ-------QQLSGKQNNLLICQGSCANPDQLQQSVTEAE-QVFGPIQGVIHAAGWASEESVENMDEAFIRRHFNAKVAGTQALVQIFADKSLDFC
LLMSSISAQLGGIGMAAYAGVNHYLDCMARYQR-SKGLPWISVNWDRWQGARGWNNAYLKRVLGERQIAVEHGLDCIEHIVQNTANCQLLVSGK------
DVLGQLNTQN--H----------------------ISIASATVADET-----------------NGLPLRV--KDRTH---LNSRFVDARNPLERLITDV
FEEHFGFSGISIHDNFFDLGASSVDLVRLHLKLNKRVDTPLTIANFLNYHSIYTLARFIEGDAATDE-----
>tr|D3HQ94|D3HQ94_LEGLN Putative polyketide synthase of type I OS=Legionella longbeachae serogroup 1 (strain NSW150) GN=LLO_0722 PE=4 SV=1
---------------------PKDWCFQLQWQHQPCIKNQKIQDNHWLLLG------KHLSRFQAQGLSVVSEEDNYPLEKLNGVLFAMGLDFPNDIESN
V-----------------------------TFQK---NTLKRLLALIKELNQKSIKLQLIVLTNAITELAAGK-LNLSNSPLIGFCRTLVLELPQFHTVL
IDSEKTDD---EHYIAQVIDELDDPYYEHIVAYRDKKRFIARLKKNKLVDR----RRSLYGEGRYLVTGGCGGLGLVTAQALLSSGAREVILTSRNVNKP
--AIEEAI---KKLKYNYTGRTIRAISLDVTDKEKLQALLVDLN-S-DGLLKGIIHAAGAAVKAALIEHTDNDIDHLFSAKVLGGWYLHELSQNIDLDFF
VVYSSISSVFGSNKESVYSGTNSFLDALIAERQ-RLGMVGTAIDWGPWGEVGMAKKRSQDQGLKQSLISNEQGHAFIKILINEQLSHAAIISPD------
YLKFML-DFV--P----------------------KPLPAFLANILI-----------------GVGQVSDQDYLEVN---VENRLQAC-IDLVTSICKE
ILEISDAEDLDENEGFFELGFDSLMITELATKLKENLAPTVTATIGFDYPSINKLAQYIESELDKHL-----
>tr|W0BHC0|W0BHC0_9GAMM KR domain/condensation domain/beta-ketoacyl synthase, N-terminal domain/beta-ketoacyl synthase, C-terminal domain/phosphopantet
---------------------PKEWAFQVQWEAVALDRNNKIQGNTWLLIG------KPLAGFRAQGLQVILEDESYSLDKLSGIIFAASLEPANDIDVM
I-----------------------------DFQK---NVIKKLLNLLKELNNKAVELQLIVLTNGIAELPAGN-LNLSNAPLVGFCKTLVLELPQYHTLL
IDVDNAGD---EHHAGRVVAEIHGDCYEHIIAYRNDKRLAARLKKITLTEK----KQTLNSKGRYLITGGCGDLGLVTAQALLSAGARELILISRQVDKP
--GLKESI---KKIQLTYSDATIRPLSLDVSNKEELRHLLSELN-E-DGLLKGIIHAAGVAIKAPLLAHQDENVDYLFSAKVNGGWYLHELSQGCNLDFF
VVYSSVSSSFGSNKESVYGAANSFLDALMAERR-RLGLVGTTIQWGPWGEIGMAKQRSRNQDLKRALIDKEQGFSFIKILINGELEHATIISPD------
YLKFML-DFV--P----------------------KPLPVCLVDELT-----------------SVEPI-SQAYLKLD---DHRRFKAC-RDMVSDICKE
ILELSATEDLNEDDGFFEIGFDSLMITEMATALKKKLEPHITVSIGFNYPSINKLAKYIESELNDYL-----
>tr|K2KT85|K2KT85_9GAMM Beta-ketoacyl synthase OS=Idiomarina xiamenensis 10-D-4 GN=A10D4_11184 PE=4 SV=1
---------------------ITHWWYKPVWRESTLKQRNSAAAERLLVFCDDLGYAKAANRIQSTQTDSILVIKGDGYSRLDDNSFQIRATHPEDYDRL
IRQLQREARLPSKIGHFFTVTDGQEPQAQMLEL-----GYFSLMWLVQAFGKLLDPLDIIVVSSGIHEVVKGEIIDPYKSMILGPCKGISQEAPHILLRN
IDICVDNS---TDLVQALRKELLAQPKDPIVAYRGGVRLLQDFEPFLVESIH---DAVLKQHGVYLITGGLGGVGLVLARHLAKKVQAKLVLCGRSALPE
--REQWSQWLRKIQELESFGAEVIVLSVDAGDEQQLKAVIDKTY-ETFGTLNGVVHAAGISESWAFKDVARDDSDYQFRPKVHGVIALQKALADKQLDFV
VLTSSVSAVLGGMTLIPYAAANIFMDNFTRIHR-TAVTRWLSVNWDTWRLSESQHETV-GKTVLEFEMSQQEGAEAFERLAYYMPSDHIVESTG------
NIQARLDQWV--R----------------------E--PFNRVNSAE-----------------PVVKTQL--YARPA---LSTTFIASSNEVEERVSKV
WHNVLGIEEIGIHDNYFDLGGTSLTAIQLVAELQREFSVPVSPVVIFEAPTVHELAKIFDDGAHKDK-----
>tr|A9AV09|A9AV09_HERA2 Beta-ketoacyl synthase OS=Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785) GN=Haur_3965 PE=4 SV=1
---------------------IADWFYTPVWEAQPLPAKGAQPAGPYLVFVDEQGFGAQVGRLESNGVTVIKVRQGGAFAQLDATSFAVRPDIRDDYAVL
FSALQTNRLLPQAIVHLWNVASNARVSADEAGFGAQVYGFYSLLHLAQAVGGLESTLPITVFSNSTQPVTGNERLYAEQSPSAVTCRVIGQENPAVFCRN
VDICVPEQ---AGLAMLLEQELLVPSQDIAVAYREGRRFVQHYRADRLEPIV---PAPLRMGGVYLITGGLGGIGTAIAGYLAEKAQAKLVLLGRTPLPP
--REEWDGLAAKIRAMEAHGAEVLTLSADVGDPAQLSAALAEIR-RRFGALHGVVHGAGHLDQSGFQDVGHEPCEAHFKPKVYALYHLEAMLRDQELDFC
LLLSSVSSVLGGLGYVGYTAANYFMDIFTHRLQ-SPSNRWISVNWDTWHLKAGQHDG--ATV-AQYELFPFEGVDAFGRILER-APVQIINSTG------
DLDTRIKQWV--L----------------------L--ESIRSNAA------------------SSSPAAS--HERPA---IDTQYVPVNSEYERRIAAV
WQQVLGIGQIGIDDNFFDLGGNSLTALQLISRLKKEFKTQISAVAIFEAPTIRAMAQYLMPDAPPAV-----
>tr|C7Q561|C7Q561_CATAD Beta-ketoacyl synthase OS=Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897) GN=Caci_7000 PE=
---------------------VLVEVLRPRWSAAPIAAGA--ALGKVVLVADTGGVAEALEVLTASGAEVVTVSGGTALTREEHAAIVAREAAEDRTTVV
D-----LRLLDR-------------PAGDAADLDGRDVVQ-PLARLLDAWG-GTGSARMLVATRGGQPVGGDVPRPA-QHAAAVLQVVANLEYLNLECGT
VDVGADAD---A-VAAALAAEIPSDVDDVLVGYRDGERHVRDYVPADAAPAP---VHRIRSGGSYLITGGLGDLGMILAEHFAASGAGRLILTSRTGSPA
--GG--SRL-DRLEALRASGVEILTPAVDVTDADAMRAVLADAL-ADGRRLDGIVHAAAVTHPDTFRAVDDEAVGLHFGAKVGGALVLDTLLETQAPEFC
LLFSSTSSILGGIAFACYAGGNAALAAIGQRNG-QSPTRWISTSWDTWSVTIDSHHV--GAVMVKHSMTREQALAAFDATLAG-PGPSLVVAAG------
GLTDRLPRAM--T----------------------L--TDVI------------------------GGGEK--FPRPD---LPQPYSAPSTDTERSLADL
WSHLLGVEPVGVKDAFFDLGGNSLLALQMLALVKKRFGVAIPAVTLFEAPTVQGLAAILDNQGATDK-----
>tr|F5LIX5|F5LIX5_9BACL Phosphopantetheine attachment domain protein OS=Paenibacillus sp. HGF7 GN=HMPREF9413_5748 PE=4 SV=1
---------------------KKNAFYGTNWMLQPAIQKTQNVQGNVLVFCDQGEYARALAEQIQHQDRLFFVSIGKKFSQID-ATQFTVGEDEEDYDKL
LA---AIGVNLCSVYHFSTVNFTRTDVSAERYGEELHQGLYSV-VYLTRAILIRDSVEFV---LLTDYAHEVACIKPANAAFLAVAKSTATEYPNLRYRC
IDIDEAT------DMETVLDEVLTENPTFRVAYRNNQRFTEALTVIEQKQ-ESMREMEIKQTGVYLITGGTGGLGLQMAIDLGNRGARTICLLARKALPD
RSTWQIESILYL----ENLGCTVLLRYTDVSDRVQMESILSEL-KEAYGPINGIIHCAGMAGDGFLFNKNMNTFRDVVRPKINGTVVLDALTRGEKLDFF
ILFSSMTSLLGGPGQSDYTAANAFLDAYAPYLR-KKGIPVQTVNWPGWSEVGMAVDYQVAD--AVTLFRSLETEVAIQALNEIIKYDLSNVIPGINYDIL
-QQ--IGENN-----LP-FRLSPWLKK---------NLDRHI-SRHQKKQVAKQTIAPDIH-----------------IIG---KN-DNYTTTENEVAFR
YAVVLDLREIDIYESFNSLGGDSIHAMELLKEINAIYPRTIDITDIFTHSSVEELAGLIDKK----------
>tr|K4Z767|K4Z767_PAEAL Polyketide synthase subunit OS=Paenibacillus alvei DSM 29 GN=PAV_8c00070 PE=4 SV=1
---------------------SQHQYRTTHWIACPDFDKAVSVVKEDD--CILIMYREQLN-------SFLMLQMRQYFGE-R-MIAVELG-EACDFDTI
LS---SLAKKIKYIVHIASLMHEEIQTVS-QLITEMELLFKSTFNLVKELLNVRHSINLV---IFTSNATKVEWIQPLSYGLSGMVNSIGREYANIKTRV
IDIDNDT------SADVLIEDMLSNESLHAVSYRRNIKYMQQLHNVTQGTTLDDEQMTLIDNGVYIITGGLGGMGLAIAQHLFSLNPTIHVVLLNR-TYS
RDTFSLEQVQSL----WAQGYSLDIMQVDIANYVQMDDTLQQL-RDTHGAICGVIHAAGIAGDGFIMNKTWQTYESVLRPKIAGTWILHELTREDPLSFF
VMCSSYASIFGAAGQSDYVAANAFLDSFSYYRR-ALGLPSLTINWTGWRESGMAVTSGIRE--EGVYVRFLNDEEGATAFWHALKTKLPQVLIGIDSKAL
-QM--EHDKP-----IISFANSSNYKG---------N---------QSHRSKGTTPEDEIV-----------------VIG---KSMSDITDIERNVIYA
WSQTLGTDQVDIHAKFFESGGNSLLAAYLQKELDKFYPGIIVITDMFVYSTVVEIAQYIEKK----------
>tr|A0A0A6PJ68|A0A0A6PJ68_9GAMM Uncharacterized protein (Fragment) OS=Candidatus Thiomargarita nelsonii GN=OT06_15295 PE=4 SV=1
---------------------LSDWLYTVAWQSKVEQLVSPQ-PDSWLILADQGGVGAKIAELLQARGHC----------------VQLYAKTSVDFEPI
LKTLFSLG-----IIHLWSLDVAGSEELLSAIEQAQRLGCESVLHLVQTL-S-EVSPRLW---LVTQGAVPVSPLNVAQSPLWGLGKVIALEHPDWWGGM
LDLAPEMPL---DAAKSLLTEIQNSQGEDQVAFRNGQRYVARLVRYRRPQIIQ--AMPLDADNTYLITGGLGALGLIFAQWMAARGAQHLALIGRSNASH
AR----EILDQL----ARNGTKVRVFQADVSCQVEMAKVLESI-KISMPPLRGIVHAAGILDDGVLVQQNWERFMRVMAPKVVGTWHLHTLTQDLPLDFF
VCFSSSSTLMGATGQGNYVAANTFMDALAHHRR-ARGLPSLSINWGVWADAGMAANLGSYDQFAEYGIGKIATKQGLQVFGELLEQNAVQVGVMVNWSKL
LQQ--FSPNN-----EPPLSELVNQIH---------QV--------TEQQPARQLEELQFK-----------------KASP-DERIARLTAYLQTQVAN
ALRLN-TAQLDVQQPLNNIGVDSLMAVELRNKVRKELGVDVPIVKFMEGASVVDLATQLSLQ----------
>tr|A0A0D6YGX9|A0A0D6YGX9_MASLA Uncharacterized protein OS=Mastigocladus laminosus UU774 GN=SP67_20875 PE=4 SV=1
-------------------------------MNSVP--NFET-SNCWLIFVHSSTALNQLINLLKQAGRVITVELGDDYKRRSQDNFVINSSRKSDFQRL
YREAFPTG-----VIFAWGNAPVAEYA------DIVYKSSHAVLNLIQTITT-QKLPDLW---LVTRNANQITSIQPQQSCLWGLGAVINQEYPQMRCVC
LDLSSTEEP---DEAEFLFQELHTFSNELRLALRQGNRYGARLVSATIPPAQK--QQFVSKEGAYLITGGLGKLGLLLAQWLSKMGASHLVLCSRNIKS-
LP----EAIASL----RQNGTQITVIGADITSAVDIQQIFSRF-GADLPPLRGVIHAAGILDDGLLSNQNWARYENVMRPKVEGTLLLDNYTRNLSLDFF
ITFSSAAVILGSPGQSSYAAANSFMDALMQKRQ-SLGLPGISINWGAWDTEN------EIEKFASWGIQSMSSDLALKYLSELIMGNVSQGVIIINLSKF
NQI--FTINQ-----L-FFAELLIAKQ---------DI----------SNSAKLLEKL--------------------SIPI-DERAESLIQGIEQILRE
VTGLSANNFIPQQTSFLELGLNSLMVLEFKNRLETNLACSLSASIIFDYPTLTSLSTYIREE----------
>tr|A0A0E8NRH9|A0A0E8NRH9_MYCTX Phenolpthiocerol synthesis type-I polyketide synthase PPSA OS=Mycobacterium tuberculosis GN=ppsA_1 PE=4 SV=1
---------------------ATNFVHTIDWQPQTVDATHPGVPGPVAIIGDD---GAALCETLEGAGQ-------------------------------
--PAMSDGVQARYVVYVADSDPAGADETV----DFAVRICTEITGLVRTLAEADKPAALW---ILTRGVHESAPSALRQSFLWGLAGVIAAEHPELWGGL
VDLAINDDL---GEFGPALAELLAKPSKSILVRRDGVVLAPALAPVRGEPARK--SLQCRPDAAYLITGGLGALGLLMADWLADRGAHRLVLTGRTPLPP
RRDWQIDAIRAL----EMRGVTVEAVAADVGCREDVQALLAARDRDGAAPIRGIIHAAGITNDQLVTSMTGDAVRQVMWPKIGGSQVLHDAFPPGSVDFF
YLTASAAGIFGIPGQGSYAAANSYLDALARARR-QQGCHTMSLDWVAWRGLGLAADAQLVSELARMGSRDITPSEAFTAWEFVDGYDVAQAVVVMPAPA-
------------------------------------GA--------GSGANAYLLPARNWS-----------------VMAA-TEVRSELEQGLRRIIAA
ELRVP-EKELDTDRPFAELGLNSLMAMAIRREAEQFVGIELSATMLFNHPTVKSLASYLAKR----------
>tr|S9T389|S9T389_PAEAL Beta-ketoacyl synthase (Fragment) OS=Paenibacillus alvei A6-6i-x GN=PAAL66ix_17562 PE=4 SV=1
---------------------GERLLYQVEWMEQARSKNTKA-NEKMVLIGNDPDIIDRFHERLNGYGPSIRVIQSDKYVEHDDNIFFVAYTNKHDVKRL
LENIR-YGKDTCKLIYISTADEAKLNNLADQLKNTVEKECSGLLHLVQSITEYSNKMKIK---VITNNVHQIAATSLYQAPLWGFTEVIRLEHTLLWDGI
IDTDTHMLK---NEIDDIINEILHGEEKQVVLGEQHKRYIPRLIRNSKSRANKELAIRIDDDAAYLITGGTGSIGQVYTEYLINRGAKNIILVSRSQASG
KL---LETMNSW----KEKGVHITLEQADVSDEADVIAMVQKL-KQNNLTIKGVVHAAGIIDDKMIKDQTWNSFENAFKTKVWGSFHLHHALQDESLDFF
VMMSSISSVVGNMGQANYAAANYFMNRFAAYRR-SLGMPAMSICWGPWEEAGMATSNSNILKIENKGLYGMSKELGKKMIDKVFHKDLASIVVVANWELF
SQR--TGVDE-----VTALSNFITDNH---------SR--------QGEQS-AAKEDVKLH-----------------ELSE-TERSEYLLSLLHKAAAD
IIGFQDINQLSVDSSFTEQGVDSLMIFSLRNEIKALLDLQVDISVFFNYPSLRKLNGYLVTE----------
>tr|Q2SW15|Q2SW15_BURTA Polyketide synthase OS=Burkholderia thailandensis (strain E264 / ATCC 700388 / DSM 13276 / CIP 106301) GN=BTH_I2363 PE=4 SV=1
--------------------DPGGWLYAPRLRQSAPLERPIDTRRHWLVLLDEHGVGARVATRLREAAQVAEIAYADEMDA-----QAIDA---------
--AAAAAADRPSSVIALWGLAAEP----ARDDDSMLKRHYIRPARLLRAWADRTGDVDVTFVADGALAAQFGAPAAPEKAMLLGLARALPAEYPGWRARV
ADVDAA----AADLVECIVAEACARSADDAAIHRHGSRWVETLEPIGAATTQ---AMAIRRDGVYLVTGGNSGMGRAIGRHLVE-RGARVVALSRRGG--
-----------------QSIPGLTAIAVDVSDLDALRRAVAQIRAEHG-PINGVVHSAGMPPHALLRTAADTAMRDVLAGKFLGARNLRQVLCADSLDFV
VLCSSLRAHVPAAGASDYMAANLALEALGASWA-ADGTRVRAIAWDTWTEIGMAT-VSDERFVPEDLTAGLSADEGVRVLEMASACE-------------
-------------SPRIAV---STRK---LDPLKARAREA---FSLARA-----------ADAHQPAAGSRHPRP-----VLAVPYVPARTALEARLATI
WSDVLGFEPIGVIDDFFDLGGDSVATLQIVARAKEQG-IHLDTHLAFGAHTIEELAAAG-VE----------
>tr|V5IZL2|V5IZL2_9PSED Polyketide synthase SpiC2 OS=Pseudomonas sp. Q71576 GN=spiC2 PE=4 SV=1
--------------------NPADWLYTPRLRQSMPLEQLIDSQRNWLVLLDDHGVGQRIAAALRDAAQVVELVYTDDTVS-----DVIHT---------
--QVEADWSRPLSVISLWSLAAQD----SSDDREVLQRHYLRPAQVLRAWADKAGDVDVTFVVNGAF---FGSPTAPEKAMLLGLARALRLEYPSWLARV
MDVEML----AQDTVECILAEATACSADDAVIHKYRSRWVETVEPVTISGGH---TLPIRRGGVYLVTGGNSGIGLAISRYLIDSWGAHVIALSRRGG--
-----------------QSGQGFTAVAANLDNIDELRQVVVSIQAEHG-PINGLVHCAGMPPHALLRTATDAAVKEVFAGKFFGALNLQRVMLQMPLDFV
VLSSSLRAHIPAAGSGDYMAANLALEALATSWA-ATGARVLSIAWDTWSKVGMAATASDARFVTDELAEGMSVEEGVKLFEAASQCG-------------
-------------LSRVVV---STRP---FSALKAHAQEA---FSVGRA-----------GEVAQRVSSTRHPRP-----ALNTVYIPARTALESQLAQI
WSEILGYDTIGIKDDFFDLGGDSVATLQIVARAREQG-LNLETSRAFEAHTIEEFAAATRIE----------
>tr|W3V5C5|W3V5C5_PHOTE Putative polyketide synthase component OS=Photorhabdus temperata subsp. khanii NC19 GN=PTE_03088 PE=4 SV=1
--------------------KNAPGLLVPFWRPVRLPGEK---------PYVVLLVDHSLAFFTSGLDKQIES-------------VSLNMLCPAQVRSA
LAGLSIGS-QKDSLVLSLAFPTDG----FS----FSPTSLQILSELGKTLAEFSTSVHIYLITSYFSRTGRLTESVLTMAALKALALVMPQEIPGINCAF
LCIQNP-------VLTGLLQTPLH-----PLKLNDEGLFVEDFRCPDAEEVL---DEARFTGKTYVITGAGGRMAGAMAKVIARRFQGRLALISRQSADS
PAMKR------LQEELKEAGAGVEIFPYALESEADALASFESIRHRLG-DISVVIHAAGVTDGDSFSPLNADHYRAQLEPKARVAEVLAKVFESIPVEYC
FVTSSMSTFFGGIAHAAYATANLFLDSWGQIQN-RRPPRWVVVNWETVHFEADPRG----D------EVAFAGAEFPALFERSLREH-------------
-------------ENQKIF---SAGQ---FMDRLYAWGGR---RTSSG-D---------RRAQLAGGVK-LKPRPE----TLTSVYQLPANDIQKEIVAI
WSGILGVDGISIDDRFMELGGDSLKTIVMAEKVYKKLGKRVSIQDFFVQPTIREIERQFLND----------
>tr|Q2SGN4|Q2SGN4_HAHCH Polyketide synthase modules and related protein OS=Hahella chejuensis (strain KCTC 2396) GN=HCH_03442 PE=4 SV=1
--------------------KNAAGMLTPFWKSIRLRKPSR----------RVLLAPASTEALTAGLTQDIEV-------------LDCNPLCSVQLRGA
LAELAAGA-RSEALTLTLAFPADG----LS----MNTESLQALADLGRALTDFSASVHIYLLAPSFLAVDQEADQVLTTAALKSLALVAPQEIPGIACAC
VEICNP-------ALASVLASPMH-----PLKLSAEGLFVEDFRSPDEEEVL---DASHFTGGTFVITGAGGRMARAMAKTLAQRFQGRLALISRQSADS
PAMQN------LRQELTAAGAGVEVFPYALESESDALALFESIRQRLG-AIQVVIHAAGVTDGDSFAPLDADRYLAQLAPKARVAQTLARVFESAPVETC
FVTSSMSAFFGGIAHAPYAAANLFLDGWSQRRN-NRLTRWVTVNWETIHFEEASPK----D------ETALLGAEFPALFERSLRER-------------
-------------ENQKIF---SAGQ---FSDRLYSWGGR---RPANGEGQ--------TS-SSVNSIK-LKPRPA----TVAAAFAAPGNALQEEIAAI
WSGILGVEGVGVDDRFMELGGDSLKTIVMAEKVYKKLGKRIAIQDFFAQPTIREIERQCLLE----------
>tr|D3V7K2|D3V7K2_XENBS Putative polyketide synthase type I OS=Xenorhabdus bovienii (strain SS-2004) GN=XBJ1_2690 PE=4 SV=1
--------------------KNTAGLLTPFWKPLRLPAEK---------PDTVLLVDQTLASLASGLDNQIEV-------------VSLDMLCPVRMRNV
LAKLSSGSSQKNSLVLSLAFPTEG----FS----FAPASLQILSELGRALAEFSTSVHIYLIAPAFSMTGYLAESVLTVAALKALALVIPQEIPGVSCAF
LSIQNP-------ALTRLLQTPLH-----PLKLNDEGLFVEDFRCPDAEEVL---DAAYFSGKTYVITGAGGRMAKAMARVIARRFQGRLALISRQPADS
PAMRS------LQEELKDAGAEVEIFPYALESEADALALFESIRRRFG-EINVVLHAAGVTDGDSFSPLNADHYCTQLAPKAQVAAVLANVFESIPVEYC
FVTSSMSAFFGGIAHAPYAAANLFLDGWGQMQN-RRLTRWVVVNWETVHFDEDRRA----D------EVALSGAEFPALFERSLREH-------------
-------------ENQKIF---SAGQ---FMDRLYAWGGR---RAAKI-D---------HRPQAGGNVK-LKPRPK----TLTSVYQSPANEMQKEIAAI
WSSILGIDGIGIDDRFMELGGDSLKTIVMAEKVYKKLGKRVSIQDFFSQPTLREIERQLVND----------
>tr|A0A0M0TCW6|A0A0M0TCW6_9ENTR Polyketide synthase OS=Xenorhabdus sp. GDc328 GN=AFK69_04015 PE=4 SV=1
--------------------NISDWFYQSVWQQDILRNK-NVKTALLFKLGDNSEQSTLYEQALINHHKIQ-VRLGQQCKLEISAPGTIRGLNSEDHANL
FKFLNNNQMSIEDIIIDC----TG----VNL---TVNEQLASVLYLLKSHRAFCNLKDITLLIQNAREVCNEPDIDPSAAAMLVISTIIRQEFHEVSCRA
IDVGHV-----KDSAEILIREIEA--GNKTVIYRNNRRWTETFLPSIPFMDE---TSRLKKEGVYLLIGGRGFIGHTFSQYLATEYNANLVISSRAKYEH
DQK---------WQSVADAAKTLEFVQADASDHDAMKKLIHDLVANYG-RIDGVFYLAGLSDDASFRSIDIGYIDSHLVPKQKGITVLEQVLEPVDYDFC
LIVSSLAPILGGVGFFAYAAASAYLDAFVLRHN-RRNKTWSLINWDGWELAE---KEKINA-VGSSLHLLVTRSEGVSLLEKVLGYE-------------
-------------EQALVI---STAD---INARIAQWSAP---AVHDNE--------------TAIQHGDYAARP-----DLDSEYVLPKSDIEKELVSV
WQDFLGIEPIGLKDDFFELGGNSLKAITLLSRIHKNCKIDVSLTHFFKNPTIEDIVILSASQ----------
>tr|A0A077QGI7|A0A077QGI7_XENBV Polyketide synthase involved in xenocoumacin synthesis OS=Xenorhabdus bovienii str. Intermedium GN=xcnH PE=4 SV=1
--------------------NMSDWLYQAAWQQHILRSE-CTKSALIFKLGSSNEQSTLFEKALLNHQKVR-VKVGSEFELEIEALSTLRCLNYDDYKNL
FDLLNNNEISIEEMVIDC----IN----VDL---SLNEQLAVVLYLLKSHRAFSPLMNVTLLTQNGVVVCNEPDINPFAAAMMSISTVIRQEFHELCCKV
IDVGAL-----NDSADKLIREIAE--DNKNVVYRNNRRWAEVFLPYSPIMDE---TSRLKKEGVYLLIGGRGFIGHTFAQYLATEYNANLIITSRSRQNI
DDK---------WQQVSNDAANLEFAQVDASDRVAMDAFIQDTTAKYG-RIDGVFYLAGLTGEASLRSIETDYIDSHLISKQKGIEVLEQVLEPVNYDFC
LILSSLAPILGGLGFFAYAAASSYLDAFVLRHN-RQNKKWTLINWDGWELAE---KTELNA-IGSSLHLLVTKEEGISLLEEVLKYE-------------
-------------KDAVVI---STAD---INARIAQWSNP---SLSKNE--------------EGSDDSGYSARP-----DLDSEYVAPNSEIEKKLVSI
WQEFLRIESIGMKDDFFDLGGNSLKAITLLSRIHKSCQIDVSLTHFFKNPTIKDIVALTDSQ----------
>tr|A0A068QR15|A0A068QR15_9ENTR Polyketide synthase involved in xenocoumacin synthesis OS=Xenorhabdus doucetiae GN=xcnH PE=4 SV=1
--------------------NMSDWFYQSVWQQDILKHK-HAKTALLFRLGECSEQSTLYKQELNNHHKIQ-VNIGSKCEFEIGIPSTLRALHVEDYENL
FRFLNKNEVPIEEIIIDC----TG----GNL---AVNEQLASALYLIKSHRAFCNLTDITLLVQNAREVCNEPDIDPRAAAMLAISTVIRQEFHEVNCRA
IDVGNP-----DDSAEILIREIEA--GNKTVIYRNNRRWTEAFLSYSPFVDN---ISCLKKEGVYLLIGGRGFIGHTFSQYLATEYHAHLVISSRSKHEY
AGDQ-------KWQSVAEASANLEFIQVNASDRVAMEKLINDMVAKYG-RIDGVFYLAGLTDDASFRSIEMEYIDSHLVPKQKGIMVLEQVLEPVDYDFC
LVISSLAPILGGVGFYAYAAASAYLDAFVSQHN-RKNKTWTLINWDGWELAE---KDKINE-VGSSLHLLVTRNEGTFLLEDVLKYE-------------
-------------RQAVVI---STAD---INARIAQWSAP---SIHDNE--------------AETQYEDYSVRP-----DLDVEYILPNSEIEEKLISI
WQDFLRIKPIGLKDDFFELGGNSLKAITLLSRIHKNCKIDVSLTYFFKNPTIEDIVILCGSQ----------
>tr|K9V185|K9V185_9CYAN 6-deoxyerythronolide-B synthase, Aspartate racemase OS=Calothrix sp. PCC 6303 GN=Cal6303_2599 PE=4 SV=1
--------------------NITDWFYLPVWKQSIPLEQETQQKLACLVFADKYEFADQFKQLLTQQEDIT-VEIGDEFCQLDRHRYVINPQRPEDYEVL
LKDLQKRDFQPNTICHYWSIAPND----ILLKENYQYFGFYSLLYLAQAIGKQDNPCKLLVVTNNLYSVIGEEKLCPQKATILGACKVIPKEYGNINCSL
VDLVIE----SVDVLNNLLAEIGKIQNNQIVAYRGSYRWLQSFEPVALDDGS---KAKFKQGGVYLITGGLGGIGLVLAEHLAKTVQAKLILIGRGGLPE
RCQWEQYQKIQKMRSLEESGMQFMVTSADVTDSQQMQAVVNQALQKFG-QINGVIHAAGVAGGG-VTQLTQEMVRNVLAAKVDGTLILDDICQQLNLDFF
VVCSSKTAILGEFGQIDYCAANAFLDAFATSRT-ASSGLTISISWDTWQEVGLAVETVLPDQKREEMKKGILPEEGIEVFNRVMGSN-------------
-------------LPHVVI---STQD---LPSLIQQSNAD---KYLEDALQ-------AGKLSSVNLSKAKHSRP-----NLGNTYVTPQTKVECILTDI
WQEILGIDQIGIHDNFFELGGNSINTIQIASNANKAG-LKLTTQQFFQHQTIAELATNLALE----------
>tr|K9QFU2|K9QFU2_9NOSO 6-deoxyerythronolide-B synthase, Phenylalanine racemase (ATP-hydrolyzing) OS=Nostoc sp. PCC 7107 GN=Nos7107_3478 PE=4 SV=1
--------------------NIAEWFYTPVWKQSRLLD-LSQKQLNCLVFVDKYGVGSEFSKQLAQQQDIT-VRLGEQFSQLDEKVYCINPQQPDDYDLL
LKALQQRDFQLNTIAHFWSVTPKY----ISL-NEYDNLSFYSLLFLAQAIGKQDDSLKLMVVTSNLYDVTGEENLCPHKATVLGPCKVIPKEYRHINCSL
VDLIIP----AAQNLDKLIAELTLEQTNEIVAYRGSHRWVQTFDVVPLEDVS---KNKLRKGGIYLITGGLGGIGLVLAEHLAKTFQSKLILVSRKGLPE
RSQWEQWLQIQKVRSLEELGAEIEVISADVTNLAQMQAVIAQALQKFG-QIHGVIHAAGVPGGG-VTQLTRDMADHVLAAKVQGTLILEEVLKDINLDFL
VLCSSKTSILGEFGQIDYCAANAFLDAYAYRNC-ISDRFTVSISWDTWQEVGFAVETVLPDQERAEIKKGILPSEGIEVFNRILASN-------------
-------------LPHVVV---STQD---LPELIKQNNSP---QYLQEQLQL-----LDSKLSSVNLAKAKHPRP-----NLGNDYIPPETEIEQILAEI
WQEILGIEKIGIYDNFFELGGNSINTIQIAAKANQAG-LQLTSQQFFHYQTIAELATDLAIT----------
>tr|W1IR82|W1IR82_9ENTR Putative polyketide synthase type I OS=Xenorhabdus cabanillasii JM26 GN=XCR1_1390018 PE=4 SV=1
--------------------KNAPGLLLPFWKPVRLPKEN---------LRAVLLLDHSLAELSNGWDTQVEM-------------TSLDMRCPMQIRNA
LTTLSGEQ-PANSLVLSLAFPPNS----FS----FATDSLHILSEWGKALAEFSTSVHIYLVLPDT--VRYLVESSLTEAALKTLALVMPQEIPGITCAF
LYLQNV----QHVSLTRLLQTSLH-----PLKLNAEGLFVEDFRCPDVEEVV---DESHFMGKTYVITGAGGRMGKAMAQVIAQRFQGRLALVSRQSADT
PAMQH------LQAELREAGASAEIFPYALETEADALALFESIRQRLG-DIHTVIHAAGVTDGDSFSPLNAGHYHAQLKPKAQVAEILAKVFEHNPVEYC
FVTSSMSAFFGGIAHAPYATANLFLDGWARRQN-QRPPRWIVVNWETIHFDGEQRR---N-------EVALSATEFPALFERSLRER-------------
-------------ENQKIF---SAGQ---FMDRLYAWGGR---RAANG-R---------SKPQTVNRIK-LKPRPN----TLTSVYQPAVSEMQKEIAAI
WSHTLGVDNMGIDDKFMELGGDSLKTIVMAEKVYKKLGKRISIQDFFAQPTIREIERQFSSE----------
>tr|A0A068QX34|A0A068QX34_9ENTR Putative polyketide synthase type I OS=Xenorhabdus doucetiae GN=XDD1_2711 PE=4 SV=1
--------------------RNSAGLLLPFWKPHRLPKETAEKTSHSLLLIDQLLLDRALASQARAWDSQIET-------------VKLNILCPKQVRNA
LVGLSPGL-HKNALVLSLAFPADG----FS----FAPDSLQTLSELGKVLAEFSNSVHIYLIASAV--IGDSAESVLTEAALKALALVLPQEIPGIDCAF
LSLQEP----N--ALTRLLQTPLH-----PLKLNSEGLFVEDFRCPDAEEVV---DESDFMGKTYVITGAGGRMAKAMAKVIAQRFQGRLALISRQSADS
AAMQR------LLLELKEDGAGVEIFPYALEREEAALALFESIRHRLG-DIHTVIHAAGVTEGDSFSPLNAEHYRAQLQPKAQVAAVLANVFESIPVEYC
FMTSSMSVFFGGIAHAPYATANLFLDGWGQRQN-RQPPRWIVVNWETVHFDEQSRP---TE------EVAFSAAEFPALFERSLRER-------------
-------------ENQKIF---SAGQ---FMDRLYAWGGR---RIANGNGN--------SKRQVTNSIK-LKPRPE----TLPSVYQSPVNETQKEIAAI
WSQILGIDGIGIDDKFMALGGDSLKTIVMAEKVYKKLGKRIAIQDFFAQPTIREIERQFLHE----------
>tr|I3TWS8|I3TWS8_TISMK DidE OS=Tistrella mobilis (strain KA081020-065) GN=didE PE=4 SV=1
--------------------DPTDWFWLPVSREIPPPSAGAVITGPVLILADALGVSAILADRLRAAHGTL-VTPGSAFAAAGPDRFTLDPADPGQFRSL
IAAL---DAEPRTILHAWALRGPR----PPAAAAVQSRGLHALLHLLQALGSPGPERRLLVAADRL-LPVTDNDLRPDHAPLLGAAKIVSQEYDRILCRM
VDPGTA----A--LADILLAELTEAEAPRVTSWRGGRRFVGEEAPRRLTGDG---RARFVPGGVTVITGGLGGMGLAFAEEVAELAPGALVLIGRSVFPD
PEDWEDWLSIRRLQAIIARGTRLMVATADVADAGAVEAVLAEARRRFG-PITALLHTAALADYEGVIHGARARTDRVMAAKLQGTLVLDQATRNDPLTLF
LLCSSLGTVLVKFGQVGYAAANEFIDAFARARA-ADPGATVAIRWSDWRDSGMSVA-----IDESDYSDGLTDLEGRLAMRRAAGQA-------------
-------------APLIGV---SQHD---LRMLVAQDPL---------R-----------AKAFLAETDRAHARP-----ALAQDYVAPRTAAEREVARI
WQRLLGIDRVGALDDFYDLGGHSLLATQVLSRITERLKVEVPLDAFLDDPTVEALAGLIDAA----------
>tr|B1ZYL3|B1ZYL3_OPITP Erythronolide synthase OS=Opitutus terrae (strain DSM 11246 / PB90-1) GN=Oter_1966 PE=4 SV=1
--------------------DPADWFYVPGWRRGLAL-APPITGGEWALIPDASGLAERLAARLRGLAARI-GADPTKLL--------------------
--------------GARWIVSLRD----VSAA--ASEPKLDELCALGRVLSSQAAETRLTVVATGLHAFPGENSAEPAKSLLLGAARVLPNEIAGMSVRV
IDVARA----ELSLLDALIAEARG--EDEFVALRGRERWMQTLEPVRLEVGE---AKPCRPGAVVVITGGFGGLGLALAESLFERARARLVLVGRS--TA
AAAAQ-----QRIDALIARGAEVITAVADVTDESALQRVHAQIRSRFG-GCQGVIHAAGVAGGG-ALARDPVAAAAVRAAKVAGTLVVDRVFGAEALDFF
VLMSSLTAQLGEFGQADYAAANAFLDAYATARR-REGVPMVAIGWDAWRDVGMAARFEPQGEL------RLTNAEGAEVLVRAVAAG-------------
-------------VPHVIV---STVD---LAWRRRQTRAP---KGTTSG-----------ATKDAVPARAAHPRP-----ALPVTFAPPQTATQRKIAAV
WEELLGVAPVGVNDDFFALGGHSLLASQAVARLRDAGVNGLTLATFFEAPTIVRLAATVAAD----------
>tr|C7PT87|C7PT87_CHIPD Erythronolide synthase, Aspartate racemase OS=Chitinophaga pinensis (strain ATCC 43595 / DSM 2588 / NCIB 11800 / UQM 2034) GN=C
--------------------TVNDWYYKLHWTPLAAKDSTSFKDRLLLVFTDNEGVSDALITLLEEKNRVR-VSPGNEFEMVSDKLFRVNYTEEKDYRLL
SDSLHALY-VLDGIIYLSGFKPMA----PAL-AAQLQTAFYGLFNACKTFSKYFKNFNLAVLTANVHAVVDDAQLSPVAALTPGMIKASLAEYYTLRTTC
VDVDGE----KTTSIATLLWEELSDEVIRFVAYRNGKRYVQELNRVDEVQGN---PYQLEQQGVYLVTGGHSGIGYEMATALATRAKATLLIIGRRSAAD
VAGQ--------IAKLEQLGSKVHYFTADISNESDMQTLFADIKKRFS-RLAGVIHSAGIGSSGVAIE-NIADVNNTFAPKVQGSILLEEHTRSLQPGFF
VVFSSIGALVPASSSADYSAANIFQDAFAAYWR-NKGRNFISINWPDWKETGLSYRKTLLQALRYSYLSPITSADGIEAFFSALSQR-------------
-------------QERFIV---VKAD---FRNFIINPYFK---IGT---------------------IKKLQGEEQ----DTESKTANGFSPTELQLAGI
WHEVLKLDQVRLEDDFYELGGHSLNIIRMLNRIEQQMNVTLPIEELLRNSTLGGIAAHIDAI----------
>tr|A0A0A0CQP4|A0A0A0CQP4_PHOLU Polyketide synthase OS=Photorhabdus luminescens GN=KS18_09965 PE=4 SV=1
--------------------RMSDWFYQHGWKQQPLSTS-SDETTLLLRLGQPLAPTCCMESSLQRYKKIK-IHVGNEKVFDLDGENQIRLDNQEDFNQF
FKLLEQSHVSVSNIVIDC----ID----SAL---AVDELLSQILHLLKSYRVQTSLKNITLLVKYAVVVCNEKSIDPSSAAVMAISTVIRQEFPDLSCRA
IDVGDM----ATDGATKLLAEIAY--GSETVAYRNNRRWCEDFVPYMPLARN---HASLKKEGTYLLIGGAGFIGKTFSNYLAKEYQANLIITSRSGSHL
DNS---------WQQINKQASSLQLIQADAKELDAMSELVQNVIKDHG-KIDGVFYLAGITGEASLRSIDKAYIQAHLEAKQKGIKVLEQALAEVDYDFC
VVISSLAPILGGLGFYAYAAASAYLDAFVIQHN-QYNNNWTLINWDGWEVAV---KSDINE-IGTSLHLLVTKEEGILLLADVLNYE-------------
-------------KDALII---STAD---INARIAQWSKP---SQLEEQG-------------NDNSNKEYSGRP-----DLECDFVTAGNEIETQLVGI
WETFLRIKPLGIEDDFFDLGGNSLKAITLLSQIHKSCNIDVPLTYFFKHPTVKEIAEFAGSQ----------
>tr|A0A0A8UQW5|A0A0A8UQW5_LEGHA 6-deoxyerythronolide-B synthase OS=Legionella hackeliae GN=LHA_2073 PE=4 SV=1
-----------------------PSLYKPVWSHQLANIDRKIREHTWIVFQDNTEIGNQLISLLRDYNKLFIVEPGKSYQLLDSNHFRISLKTKSDYLKL
FEHLKT-ELKHPILFHTTSCNPLFGKLSNEEIDTQLNASFYSLLFIAQAYREIDTPLRCGVLTQGTQRILGTELISPVNASLIGACRVISQEHPNIVCKV
IDSNPVEFSSSKNTCLSLLNNDDWLTQNILTAYRNGYQWDLSYTLAETTKIH----NRFRDKGIYLITGGLGGIGLAVSELITEEVNNPTLIFLSRTPML
PETKLYPKIKLL-NHLKQKGADLYFYNVDIADSEALRETIQQCKTKFG-AINGLIHCAGVAGGGLVQLKTREIADTVFRPKIHGTFNLLKAFKDISLDFV
VLMSSIAALTGEQGQIDYCAANACLDAFALSNA-FQSKFVISLNWNTWRDVGMAIETKLNWLD--RG-NDISPEQGKQVFLQALRTNF------------
--------------TNLAVSNFD-------IKS-YSKLV---MEKD----NV--------SGSPDIRASRTDL-------NIANNYQAPRNSIESQLAQL
WQESLGIENIGTEDNFFDLGGHSLKALKLIEKINRHFHRSLVINQLYQTPTIAELSDVISS-----------
>tr|D5T6Q8|D5T6Q8_LEGP2 Polyketide synthase module OS=Legionella pneumophila serogroup 1 (strain 2300/99 Alcoy) GN=lpa_03123 PE=4 SV=1
-----------------------CSLYKPLWSHEKIAVTANLKNFDYVIFKDKTGIGQKIINILKNHDEPIVVELSEEFRQLSKTHISINPGEKSDYNQF
VSSLKN-TLRHPIIFHCFSCDSSESFLDTQQIENRLKLGFYSLLYLTQAFLNDNIPIRLAIITSGTQNVIGTEKISPINASLVGASRVIPQEHHNISCEL
FDINLYETTQNITNAIIIVSQAAQDLPYQLTAYRNSYRWELSYSPNHNKTVL----QRLTDNGIYIITGGLGGIGLSLCHSILKNTKSPTFILCSRTPVI
DESPHHHKVLQL-KKLKELGAAIVCYQAHIGNDKDVDRFITFCKSRFK-TINGLIHAAGVAGGGLLQLKTKENADNILLPKIHGTYHLAKALREFHLDFV
VFMSSIASITGERGQIDYCAANACLDTFANSNL-FYTQCLLSINWNTWRDVGMSVETQIDFFA--RG-NTISPLQGQELFLKALSSNC------------
--------------SNLIVSNYN-------IED-YSSLI---LDNN----P---------ADTEEHKVSRDTF-------SMSHEFCAPQGSIEKRLAKL
WQDNLHIVDIGRNDDFFALGGHSLKALHLIENINSILGVNLSIQHLYQAPTIAKLAELIYS-----------
>tr|Q5WUR2|Q5WUR2_LEGPL Uncharacterized protein OS=Legionella pneumophila (strain Lens) GN=lpl2106 PE=4 SV=1
-----------------------CSFYKPVWSHEKIAVIAHLKNFDYVIFKDKSGIGQNIINILKNHDEPIIIEPGQEFRRLSKTHININPGEKSDYNQF
VSVLKN-TLRNPIIFHCFSCDSSEDFLDAQQIENGLNLGFYSLLYLTQAFLNDNMPIHLAIITTGTQNVIGAEKISPINASLVGASRVIPLEHHNISCAL
FDIHLYETTQNITNVVIIVNQVVKDLPCQLTAYRNGYRWELSYSSNHSKTVL----QRLTDNGIYLVTGGLGGIGLSLCHSILKNTKHPTFILCSRKPVI
DESPYHHKALQL-QKLKINGATVVCYQANIGNDKDVDRLITFCKSRFK-TINGLIHAAGVAGGGLLQLKTKASADNILLPKIHGTYYLAKALRQFHLDFV
VFMSSIASITGERGQIDYCAANACLDAFANSNL-FHTQCLLSINWNTWCDIGMSVETQIDFFA--RG-NTISPLQGQELFLKALSSNC------------
--------------SNLIVSNYN-------IED-YSSLI---LDNN----P---------ADTEEHKVSRDTF-------SMSHEFCAPQGSIEKRLAKL
WQGNLHIVDIGRNDDFFALGGHSLKALHLIENINSILGVNLSIQHLYQAPTIAKLAELICS-----------
>tr|D3HN57|D3HN57_LEGLN Putative polyketide synthase OS=Legionella longbeachae serogroup 1 (strain NSW150) GN=LLO_3443 PE=4 SV=1
-----------------------TVLYSPVWTRGALSVNTKISDYQWVVFKDSMDIGQQIINVLSFYNRPIIIESGDEFIIHSQSHFTINPVVKEHYIDC
FKCLRE-TLNHPKLIHCWSLDENQGLDDDATIEASFDKGFYSLMYVIQSFVEVKNELGFCIITRGTQHILGTERLSPANATLSSFCRVVPLEHPLIRCLM
ADIDRDVKGVELTAIFAILADKS---RDILVAYRNNYRWLPAYVAIENNSLK----TRLSDNGIYLITGGLGGVGLALSEAIASQVCQPVLILSSRKPYP
PQEEDHDTVSRL-KYIQSLGASINLYPCDVTNDQDVSQLLHWIFLKYG-KLNGLIHAAGRAGNGVLQLKTHEKAYQVLSTKIYGAYYLAKATQKLILDFV
VLMSSIAAVVGAKGQIDYSAANASLDAMAQSNL-FHSKFTLSLNWNTWRDVGMSVHSSLNLLN--LG-NDISSKEGQSLFLNALSTSY------------
--------------RQLVISNYE-------LDR-YQALL---ANTV----NE--------KEETKNKVSRKHL-------NIKNTYSEPQDELEKQLAKL
WQECLHIDSIGREDNFFALGGHSLKAMTLIEQMNTLFNCSLSIQHMYKAPTIALLRQLISE-----------
>tr|A0A098G7E3|A0A098G7E3_9GAMM Polyketide synthase module OS=Legionella fallonii LLAP-10 GN=LFA_3028 PE=4 SV=1
-----------------------GALYKPVWSYEAIEHPSHLNEFNYILFKDKTGIGEQIAEILIKQGKPIVIEQGQEFKQLSPTHFTINVSEPSHYTQL
MSSLKD-TLHHPIILHCFSYDDVQEFLDTAQIEHRLHLGFYSLLYMTQSLLSETIPIHVALITSGTQRIVGTENICPINASLLGSSRVIPLEHHNISCEF
IDINTKDNVALI---LNLLNQKQKEKSHKVTAYRNGYRWELSYAPFQSKTPS----NRFSDHGIYLITGGLGGIGLALSNAIARHAVSPTLILCSRKAIP
PQSPYHTKIEQL-HQLKELGANIECFQADIGNYEEVVDVVTFCKNNFG-RINGVIHAAGIAGGGLIQLKTKEAVHQVLVSKIHGTYHLAKALQEFNLDFV
VLMSSIASITGEQGQMDYCAANACLDSFAQSHL-FHTSCLLNINWNTWREVGMSVETNMSLFS--RG-NTISPTQGQELFLKALASRC------------
--------------SNLVTSNYS-------VEE-YDQLI---RDNK----P---------IIDEEHKVSRDTF-------HMNQEFKAPKGPIEKQLATL
WQENLHIVAIGREDDFFALGGHSLKALTLIEHINTTLGTHLSIQHLYQAPTIAQLAEVIGA-----------
>tr|G8NU16|G8NU16_GRAMM Long-chain-fatty-acid--CoA ligase., 6-deoxyerythronolide-B synthase OS=Granulicella mallensis (strain ATCC BAA-1857 / DSM 23137
-----------------------AVLYRRHWELLKSTPGRSASVGHWLILADSGGVGAQLAELSRKGNCSLISEVEVE--KLS-----LNDQTL------
---------QG--VVHLGSLDLEPDMAG----RSKVSSS---VLALVRMLKGNGSKTHLWLVTAGAMPILEQDVPAVSQAALWGLGQAIEAEHPELWGGL
LDVDPARPSA----CLLAIE------GEARLALRDGQRYAAKILHDHQPMES----NLFEENATYLITGGVGGLGTRLTKWLLER-AGNVALLGR-----
-----------T-VPQQSVNEKTRFFRCDLANTDETMAVVREIENSMP-PLKGIFHLAGTLDDGLLLAQDGERFYRSGAGKAEGAWNLHLASRDIALDHF
VLFSSMASLVTLPGQGSYAAANFVLDTLAHHRR-ATGKPALSVNWGPWADLGMAATEYVERMSS-FG-VAALPADALTMLGQLMSSGAIQI---------
------------GVTQLASAKLS-------RKS-VSAIT---SSQL----A-GL-----PTERHEGLDRDTEF-------VIALRSCASVDWLAARLLEI
FSETLRVEAITSTQSFLEMGGDSILALELTNRLSSTLGRTLPGTLLFTFPTIAALTDHLLR-----------
>tr|A0A081PA50|A0A081PA50_9BACL Uncharacterized protein OS=Paenibacillus sp. MSt1 GN=ET33_12790 PE=4 SV=1
-----------------------QWLYEPVFRPTTAITWPKECSGLWVVFEEERGGWMDVLERLEHASPVVRIREASGFEQLSERVYGLNPARLEQYALL
FDALAA-GEGPMRVLCSWAEPDSPGGV----------SGFLQLSRALQAHAGEGNSAHLCIVAEGLYNIAGETDIRPERMTVAGLGQVWMQEHALAAFHL
ADALMPSRRSQADAILEFMS------AGSPRIYRGNQRWMLEYEPVHAKRPE----EEAQAAGTYLLIGPFDRKMQAFAQYLVQPGLTRIVIINEQPVMP
DKAAARQAAAHA-LRLEELGAEVHFVPIAFPKQRALAEAVDQAAALYG-EVTGVLYTDWSSEEMTFTAADGQAVEAELDRTAQGLDELARALAPHRPDFC
LIQSSIASELGGLGLSLHAAAAAYTEAFVRRHE-LTDSRWRCIQWDAWTSGPVSSDREVSELA---R-LAIRPEEGVRLWTKLMACDTI-----------
--------------SQCLVSTAD-------FAA-RRAYA---LQSQ----NRQAE---QTGPGKGNLALRPRP-------ALTVPLVTPRHDMEQQLADA
WSELLGMEPIGIHDDFFNLGGHSLLATQVISWVNSHFPIEFPLKLFFEYPTVAEVAEAIEA-----------
>tr|V3T1K6|V3T1K6_9ENTR Beta-ketoacyl-acyl-carrier-protein synthase I, 6-deoxyerythronolide-B synthase OS=Serratia sp. ATCC 39006 GN=Ser39006_03352 PE=
-----------------------QWFYRPTWRPLALADGTPPPAGCILVFMDDIGVASECSILSAQGHTPIAVAKSSSFRQFGERSFAINPACLQDYLDL
FSALRGRLGEDLQLYHFFSLGKPEDPLDADDIAPMMSVGFYSLLHIANALAE--TTNTLSVISNHLYQIAAEQHTAGAKGALQAACLVIPQEHPHIQCHS
IDVMVPDHPRQSRLIQQLCFLMAKSSRPAAAILRDNSLWGRSYERLAANAAQ-TAATPIRKRGVYLITGGFGSIGRLLASHLATQYQASVILSTRGMDDN
--TEGREKHQWLQTL-RASGAQVEIICADVTDYHAMEKGLA-VAEEICGAVNGVIHCAGLVGQMYLKPTAPTDCEEIFSAKITGVQVLAALFEGKKDFCL
CMSSISSVL-GGLGHAAYIAANIYMDYFVQQQNL-----TADFRWLSVNWDGWQTERMQAQRITQDKF-AMSPAEGIAACEWALAQNETDLL--------
-----VHSTA----------DLDARIKQWVTLDSLQ---DQPR-------SVFPRPQ----------LDTPY--------------VAPEDTLQQALCTM
MQERLGVDKIGINDDFFQLNMDSFIIVQITNMIKKQLNVDIPVVTFYKYPNINVLSAIIQQLGY--------
>tr|K2KT85|K2KT85_9GAMM Beta-ketoacyl synthase OS=Idiomarina xiamenensis 10-D-4 GN=A10D4_11184 PE=4 SV=1
-----------------------YCVSTPVWQQSNLV-TQITEQLRWIVLGKELSLCQRLEQLSVKGIEPICVVEGEQTEATDDNHWIVNPNQPHALEAL
IKEAE-LGLQSVRVLNLWPLAVTLDDTAKKRLL-----RVREALDASQALES--VFVQLLRVTQGAQSVTGEEELYAEQALLS-IELALNDSEKQKQWRT
LDVMLPAPQSALTLAEQLVSEMGASSEQSCLALRGKHRWVKSVDTINLELGS-QDYLNDVKGRTFALVDGVNDLGLTIAYQLACAGAANIIVATNETLDR
STDVLAQKIWQLKVI-EDNGCSVQLIVEDSKTELGAAAIYQ-HAKASDSPLHSVLLMT----QGHIQSC--LESITALS-KVTQDSGADERFNVEPEHRL
LLQSYQNALAGT----AACAAK------------VS-SIICHIGKGNLQWEEA-----------------------SAAVLRIMSAHLNVAY--------
-----YTANS----------------SVETETESYA---AALS-------SRYQRPE----------LENEY--------------RAPETQLQKQLAGI
WTDLLCIDAIGIDDNFFELGGHSLLATRLFARINRDFGLSLQLRNIFESSTIAEQADLIEVLLQ--------
>tr|A9AV09|A9AV09_HERA2 Beta-ketoacyl synthase OS=Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785) GN=Haur_3965 PE=4 SV=1
-----------------------DWLAAPSWKRSIQAAARLAEPHCWLMLADE-GLAAETAWLEQRGQTVITVMPGASFAALGQARYMLRPTSREDFTAL
LQTLERQGHAPSRVVHCWLFGAQEDALSDATLTATLDVGFYSLLALAQALGD--QGV-INAVTAAMQEVTGQENLQVAASTVIGPCKIIPQEYPNLTARS
IDILLPAGA-ATALVAQLGTELATPPTGDQVAFRGAHRWVQVFEPITVPAAP-ASHPRLRTGGVYLLTGGLGGIALGLARDLAATLQAKLVLVNRSGLDR
AEQGVGRRIQQVLDL-EVLGAEVLVIQADVTDTVAMARAVA-EAQARFGTIHGVLHTAGVPGVGLMQLKDAATAAAELAPKVQGTLALTS--AGIPDFLV
LFSSVTSATGGGPGQVAYCAANAFLDAYARKHATDH-GQTVAVSWGEWLWDAWSEGL-QGFAAYRTTF-GITFDEGADILRRILAEPLAHVF--------
-----VTSEDLLP-----MAERSRRESRGLEELQRQ---QEAR-------PTYPRPE----------VGTSF--------------VEPQSVIEQQIAGI
WSTVLGIAPIGLHDNFFDLGGNSLLGLDLFSRIRKALKVDKPAYVLYEAPTVATQAAYLTPAPE--------
>tr|C7Q561|C7Q561_CATAD Beta-ketoacyl synthase OS=Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897) GN=Caci_7000 PE=
-----------------------QWLHLPVWRQTAAP-AAVDLPESWLVFSRD-GVADRVERLRGSGAAVTVVRPGAAYA---EGDYAIRPGNLDDTRQL
LRDLRVAGGVPSRVVHLWALGSSDPV----------VDGLHTLVALARAAGE--VGV-LDVVTAGAQQVLPGDATDPLAATLTGPALVVPVEYPSVTARL
IDLDAQP----PKTVAALTAELARPAADRIVALRHGRRWVCGFETMPEEALP-SAAPILRESGVYLITGGLGGIALGMAERLAAECHAKLVLFGRTGLPR
ETDETRERVRKVQAL-LDLGADVEIVVGDLGRPEDVRRAVT-TALDRFGALHGVLHAAGLPGMGLMQFKEPGELDTVLAPKVAGTLALAE--EEIPDFLV
LFSSITSATGGGPGQVDYCSANAFLDAFAAQQSAAG-RPVVSVDWGEWLWNAWSAGL-DGYAENRTRI-GIGFDEGWRCLLRALASGEPRVV--------
-----VSTQDFGS-----LVRLSAEFTD-AVAATAA---LDGG-------ALHPRPE----------LMTPF--------------QEPEGATEETIARM
WRESLRLDGVGALDNFFELGGNSLLGVTIVTALRKEFGLDDPPHTLYEAPTVAALAEVVDKARS--------
>tr|A0A089NFM6|A0A089NFM6_9BACL Polyketide synthase OS=Paenibacillus graminis GN=PGRAT_09285 PE=4 SV=1
--------IFKPDFGDNSGSNARKWLHEWKWRPEPLAEDNSLAAGAVLVWKGETEFGRELESVLDTERNPVYVSFGDEPHYDGDRSFTIRMDREEDYSAM
LRQLPG---AVSAVIHLSNYAREKLRT-PELLTQAVNDGIWSLYFLGQTLVLQGRDVRLIIVTNKAFRLEGDQEPAQTAAAAVGQVI--DLEHEGIHVSV
LDMNKDEYLTGQEFAAALNASLKLRNDGEVTAIRSGTAYLRTLERMPEQVAG--EGFEPYSGETYLITGGTGLVGSRIAEALVRQAQINLVITGRRPVPA
EPG----RLLELEK----LGAQVMYAAVDVTSRTQMEELLDRIHAVYG-PLHGVIHAAGRMEYAKLLARSQDEIEQVLAPKWQGTIITDLVTRQEPLRFF
AALSSVSASAWASGLGDYAAANAFLNGYCIFRA-GDPGRSLSINYSLWKDTGAGTDKLVDLALKGQGLQPLAHEEAAAAFLRALSSTGSDVHV-LDLVEP
EYSALPSRQQEPMRVAERPFTHR--STREIRDIVYQAIGEELR---------------------------------------------------------
----ISIRNLDAGMNFTELGLDSVGATRVVADIGGKLNTELYPTLIFEYQTPEALASHIAEQ----------
>tr|X4ZXT0|X4ZXT0_9BACL Beta-ketoacyl synthase OS=Paenibacillus sabinae T27 GN=PSAB_07810 PE=4 SV=1
--------TFKPDFGADSEANGSGLFHEWQWKPADLTGGTLFNEGALIVWNGNLEIGGELERLTDTERNPVYAASGDKFHFDGKRSFTIRPDHAEDYADL
LEQVPG---RLSAVIHLSHYLQEELHA-ENLLKG-VNEHFYSLLYLGQGLVRHGSDVQLVIVTDKAYALPDDAGPNQAAAATLGQVI--GTENDGIRVSI
VDMNKQEYPSGRELAKALTLAIQQQADEEISAIRGGVRYERTLEKMPAPAVG--QAINLNDGETYLITGGTGLVGGQIALALARQARINVVLTGRKQLPP
DHP----LLPKLEE----LGAQVMYAAVDVTDQAQMEELLRSIHAAYG-PLHGVVHAAGQLEYTKILSRSVNDMDSILAPKWKGTIITDLVTRQEPLRFF
AALSSVSATAWASGLGDYAAANAFLNSYSSYRT-KVPGRSLSVNFSLWSDTGAGTENLLELTLRSQGLKPLAHSRAADAFLRALGTARPDIHI-LDLVKT
ERPAALKAERHPAAAAARTQVYH--TAKEIRETVYRTIAGQLQ---------------------------------------------------------
----IPVSHLEAGKNFMELGLDSLGAVQVVSKLGGIFNTELYPTLIFEYQTPEELSAHIVEL----------
>tr|A0A089ISP4|A0A089ISP4_PAEDU Polyketide synthase OS=Paenibacillus durus GN=PDUR_08950 PE=4 SV=1
--------TFKPDFGESSGGYGRSLFHEWVWKSEPFADDYRLPEGAVLVWNVSPDIGRELESLLDPERNPVYLSFGDKLQYDGERSFTVRVDQAEDYSAL
LQQVPG---NLAAVIHLSNYSQDKLPA-SALLNSVLNESFYSLFHLSQAIVRHESNVQLVIVTNKAFMLEGDQGPVQAAAVTLGQVI--DLENEGIRVSA
IDMDRDEYPSDRDFAAALSNAMKQQTDTEIAAIRSGARYVRALEKMSVQADR--ESIELHDGETYLITGGTGLVGGRIAAALARQARINVVLTGRRKLPP
DNG----LIPELEE----LGAQVIYAAVDVTDQAQMEDLLRKIHDAYG-PLHGVIHAAGQLEYAKLLTRSLGDIDNMLAPKLNGTVITDLVTRQEPLRFF
VTLSSVSASAWASGLGDYAAANAFLNGYSCYRA-NDPGRSLSINYSLWKDTGAGTEDLLQLTLKAQGLKPLAHEEAAAAFLRALASTGPDIHI-LDLLKA
ESFTAPRTERTTVAV-RQASVYR--SAREIREIVYQAIAEQLQ---------------------------------------------------------
----ISVRSLEVGMNFMELGLDSVGATKVIAELGSRLNTELYPTLIFEYQTPEALSAHIEEI----------
>tr|A0A0F7CGZ1|A0A0F7CGZ1_PAEDU Polyketide synthase OS=Paenibacillus durus ATCC 35681 GN=VK70_04635 PE=4 SV=1
--------TFKPDFGAGSEASGSGLFHEWQWKPAALESNTKINEGAVLVWNGNLEIGGELERLMDAERNPVYVASGDKFHFDGKRSFTLRSGNAEDYADL
LEQLPS---KLSVVIHLSNYLQDELQT-ENLLNS-INENFYSLLHFGQGIVRHGSQVHLVVVTNKAYNLLADAGPNQAAVATLCQVI--DLENDGIQVSV
IDMNKEEYSSDRDFVKALTTAMKQKADEEIAAIRGGVRYVRTLEKMPAPAVG--KGIELHDGETYLITGGTGLVGGQIALALARQARINVVLTGRRQLPP
DHR----LLPKLEE----LGAQVMYAAVDVTDQAQMEELLRKIHASYG-ALHGVVHAAGQLEYTKLLSRSVSDIDSVLAPKWKGTIITDLVTRKEPLRFF
ATLSSVSATAWASGLGDYAAANAFLNGYSSYRT-KEPGRSLSVNFSLWSDTGAGTEDILELTLRSQGLKPLVHSKAADAFLRALGTARPDIHI-LDRIKS
ERSTVLNAERQPAAS-SHSLVYR--SAKEIREMVYRTIAEQLQ---------------------------------------------------------
----IPVSHLETGRNFMELGLDSLGAVQVVSKLGSLFNTELYPTLIFEYQTPEELSAHIEEV----------
>tr|M1MZ76|M1MZ76_9CLOT Polyketide synthase modules OS=Clostridium saccharoperbutylacetonicum N1-4(HMT) GN=Cspa_c29360 PE=4 SV=1
--------TYKPDFGRESIKVPNEWFYNWKWAPGFQEAFSSLQAGNVVIFDDGSGINEEVEKLLDPDKNKVSIRAGETYSYDGDRKFVVNPLIESEYVEV
FNAIPG---SIATVIHLWNLKQEISNL--EAVFRVINGNLYSVLYIGKALSRLNEGIKLLLATNLGVPIDEKHKPHQSIAITLTLAL--DQENSFINAHC
VDLDKNEFESNREIAKVLFNEIMSETNSEIVVIRDGVRYIRDLINVIELNET--SEIKFKDGETYLITGGLSAVGGAIAKAIVKKAKVNLVLTGRKELPL
REE----LILELEE----FGASVSYEVVDVTKMDDMKALMIRINNRYG-SIHGVIHAAGTVDSSKLLNKEIQVVNDVIEPKLQGAVITDLVTRKEPLKFF
VMISSVSCSIWSAGLGDYSAANSFLSAYSFYRA-GQPGKSIAINYSLWASIGMGADEGADLALKAQGLNPLAPKKAVEAFMRVLSDGNQSVHI-IDKIEN
EASK------------AVKFNFK--KVNNVKEVVYSVIAEQLH---------------------------------------------------------
----IEKDHLDIGQNFLELGLDSLGAIKVMETLGNKLGMELYPTLIFEYQTPETLAEYIEKV----------
>tr|A0A0E4H8A7|A0A0E4H8A7_9BACL Beta-ketoacyl synthase OS=Paenibacillus riograndensis SBR5 GN=PRIO_1961 PE=4 SV=1
--------IFKPDFGDASGSHARKWLYEWKWRPEPLAEDNSLAAGAVLVWKGETEFGKELESLLDPERNPVYISFGNEPHYDGDRSFTIRMDREEDYSTM
LRQLPG---AVSAVIHLSNYAREKLGT-AELLTQALNDGIWSLYFLGQALVLQGSDVRLVIVTNKAFRLEGDLEPAQAAAAAVGQVI--DLEHEGIHVSV
LDMNKEDYPSGREFAAALHTSLLLRADGEVTAIRSGTAYSRSLERMPEQAAG--EVFEPCSGETYLITGGTGLVGSRIAEALARQARINLVITGRKPVPA
NPE----LLLELEK----LGAQVMYAAVDVTSRAQMEELLARIHDVYG-PLHGVIHAAGQMEYAKLLTRSQDEIEQVLAPKWQGTIIADLVTRQEPLRFF
AALSSVSASAWASGLGDYAAANAFLNGYCIYRA-GDPGRSLSINYSLWKDTGAGTDRLVELALKGQGLQPLAHEAAAAVFLRALSSPGSDVHV-LDLVEP
EAFALPPSRQEPARLAEQKFIHR--SAREIRDIVYQAIGEELR---------------------------------------------------------
----ISVRHLETGMNFTELGLDSVGATRVVADIGGKLGTELYPTLIFEYQTPEALASHIAEQ----------
>tr|A0A0M2JC79|A0A0M2JC79_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces mangrovisoli GN=WN71_31690 PE=4 SV=1
--------RFGT------IGRTHP------WLADHLIMDSVIMPGAAFVEADLAGCDHEMEPLVLPERGGIVQTTVGEPDESGRRPLTVHSRPEDDTEAP
FVHVSG---TLATARTAAPYDFTEWTP-VEAAPGGDGEA-WAVLGLALWLADDR-DARLVLVTRGALPLDGR--PDPAAAAVWGLVRSAESENPGRFV-L
VDVDPA--AAWPTVTGALRRA--VATEEPLALYDGEIRAARLTALPPTETGA--EPASWSADGTVLVTGGTGGLGALVARHLATVHGVRHLLTSRRGPDA
P-E----LAAELGE----LGARATIAACDVADRAALADLLAGIDPAH--PLTAVVHTAGTVADG--PSLTPDHLDDVLRPKLDGALNLHELTAEHDLDAF
VLFSSAATVFGSPGQANYAAANAFLDALAHQRR-AAGLPAVSLAWGVWAESGGMAREGDLKRLARAGAAAMTAAQGLALFDAAVTAAGAEVPMRSGELPP
SLVRVPR-RRSAAAEAGSPLTDL--DAKELLDLVRGHAATVGH---------------------------------------------------------
----GSGSSLAAQRTFKELGFDSLTAVELRNRLTTATGLRLPATLIFNYPTPTALAAHLHTE----------
>tr|A0A060LNM6|A0A060LNM6_9BACI Uncharacterized protein OS=Bacillus lehensis G1 GN=BleG1_0358 PE=4 SV=1
--------TFSPSFGDYSNAQLLRWFHEWQWVEDLGKAYQPDRNGVTLVVSSESDCHRSIAYLRETGEDLIRVENGSTFNQKDSYCFTVNPSKASDWEHL
KSVLPS---DIKNVVFLSYGSQKVGDE--K-----YIESWKDFLTLASFTSMQSNQMRILVVTKQLHPLMKTDSPYQALDATFANVL--DTEAHVYAS-T
IDVEED------DCGVVIEEELKRFPPEEVALIRKGKRYVRALTQNRQMSFE--DEINIEENDTYVFTGGAGSIGSEIALELASKAPINLVITGLTPLEE
SEQ----LFSRLKS----LGARVSYFAVDVGNRQEMDRVLTEVRTLYG-RVDGVIHGAGLLSPESLMKRDQESVKAVLNPKINGTRVLDELTRNDSLKFF
VMLSSISASIWSAGLGDYAAANAFLDQYSYYRT-TKPGKTIAINYSLWEKEGIARSSLSTFIKKTQGLESVSSSLGSKVFFQALNANGEPLHV-LKEKTN
SPM-----KREPIEKAKQQNVTL--EKGAIRNLVYQITADQLQ---------------------------------------------------------
----CPVDELETNRNFEELGIDSIRAVTVLDQIAQSLKLELNPTLLFEYQTPYELSKYLEDV----------
>tr|B9E1U5|B9E1U5_CLOK1 Uncharacterized protein OS=Clostridium kluyveri (strain NBRC 12016) GN=CKR_1419 PE=4 SV=1
--------TYRPDFGMENIKVPNSWFYSWNWKAELDNSLSSLPAGSVVIFDDGNGIGEEFKSMFDEKENKIVVSLGSEYSWDSNKNFIINPLVEKDYIEL
FKNIPE---PIAAVIHLWNLKREAWKS--EFVFRVIQEDIYSILCIGKALKELNENIRLLLATNSGISVTENYKPHQSITVTLALAL--DQENTFINSCC
IDIDKKEYKSNKELAEILFNEIGKEINDEILVIRGGIRYVRDLINTGELNKY--SKIQFNDGETYLITGGASAVGGEIAKAFAKKAKVNLVLTGREKLPL
IEE----LILSLEK----LGANVTYEAVDVTKINEMEVLMEKVNNIYG-SIQGVIHAAGTWDFSKLLDKSIDTVNSVIEPKVQGAVITDYVTRKEPLKFF
VMLSSVSSSIWSAGLGDYAAANSFLSTYSFHRA-SEPGKTIALNYSLWAKTGMGANNMASMAVKVQGLNPLPAEKAVEALMRVLSDGSQRIHI-LDKLEI
KPLS------------VNTLDFK--KSQNIRETVCKIIADQLQ---------------------------------------------------------
----VHQEELDIGQNFLELGLDSLGAVKVMEKLGHNLGIELYPTLIFEYQTPDSLAQYIEKV----------
>tr|A7GTF8|A7GTF8_BACCN Beta-ketoacyl synthase OS=Bacillus cytotoxicus (strain DSM 22905 / CIP 110041 / 391-98 / NVH 391-98) GN=Bcer98_3193 PE=4 SV=1
--------IFKPDFGEEL--RFMDWLYEWKWEMETPLYIENDKRGSILVFDDEQQVGKEVCGILEQINTSVVVIPGNEFHYDGDTRFTIRPESIEDYMMM
LQHIQG---DSISIIHLWNGTKESVTP-TLFLQSALFQTSYSIILMAKALKIKAKNVEFIVVTDRAFAVLQDEEPQQSISAVIGQVI--DQENSEFSSCI
LDVDNRAYENKFELAELIVRELSMGRQEEIVAIRGGKRFVRKLERIV-PSKK--QEITIQDNETYVITGGTGHIGGEIARAFFKKAKVNLVLTGREQLPS
REN----VIQDLEN----QGAKVEYFAVDVTNEQKMKEMIQAVKQLYG-SIHGVVHAAGTIHHSKLLSKDLNDIQQVMSSKVQGTIIADMVTRQEPLKFF
VTLSSISASIWAANLGDYAAANAFLNGYSQYRK-NTPGRSLSINYSLWADKGLSEMDLSALAVKAQKLNPLSSEGGTQAFFEVLQYEGKSVHI-LDRQED
NVAE----KVVVLSPSAHPVRYK--TAKEIKEIVYQVIAAEIN---------------------------------------------------------
----CDAESLEVTKNFLELSIDSLKATKVIAEIGKQLNTELYPTLLFEYQTPEALAEYIEKT----------
>tr|W4DZ45|W4DZ45_9BACL Linear gramicidin synthetase subunit D OS=Paenibacillus sp. FSL R7-277 GN=C173_11855 PE=4 SV=1
--GKYDAVLKKLEI-VRNKNTVKPWIFKKVWKPLSLEEGTVPC-VNILVFEDRHGLAGEFIECMGDETRVISVKQEDCFQVYDRNHYGCDYTRYEGCKEL
FDYFKQIGWKADHMIYLPTYQIN--ASGDTDISSSSQLGVFSLIHLLQVLADNDASTSLYVGSSNVFQDAGGLGTRYDNAALIGFMATLDTENTGLRSLL
IDLEGRDI---KQDARLLRAEIMHGETVKEISYRDGRRLTWKLRNVPLRKAE--PKTRIKQGGNYVVTGGLGGIGTKICSQLIENYQANLLILGRSDLGT
LEDNDS-RVQ-HYNQLVALGTSISYRQADVCDLDSIVQAVEDYEQSKGIQIDGIIHLAGNSSSYLITAIEQQTFAEEFNAKVYGVLNLFELLKSRKEAML
ITFSSVTSLLGSATFSAYAAGNSFLEMFCKYAAGQLGYAVKCISWTMWDKIGMTAGSLINSLSESIGQHVISEQDGLLFFEALLNLGDDMVYVGIDENNV
HISHRIDEKVYAKEYLAVYRQ-------EDTEALLQLENAKVLDDYGA-----VSTLKMLTVNRDGEV--------IEEEQAEPYVEA-STDAERIISNI
WSEVLAAGKIGMNDNFFELGGHSLKATQVVSRIKKEYGIEFAINDLFYHPTVGALAKLVEE-----------
>tr|A0A0M0WWP6|A0A0M0WWP6_9BACI Phosphopantetheine attachment protein OS=Lysinibacillus sp. FJAT-14745 GN=AMS59_10485 PE=4 SV=1
------------------------SFYGLRWTPQAAEEREFSPEGNILILADRSGFAKELTDRIQTADNLYFVSFGEVYAQLDSTHYTVG-GAEEDYVKL
LEDI---GVDFSTVYHLSTLDFNQSDYTLEQYPETLNQGLYNLAYLTRSFLKINGNVNFVLVTEHAHDVDGEEAIKPANASFLALAKTTQAECPEYEYRS
IDIDSR-T----DMNTVLNEVLRSGEQTFRVAYRNNVRYTEVLTALDVQRD-DIEVVKIKKEGVYLITGGTGGLGLETALNLGGLGPCNICLIGRRQLPA
VLKKDKDLIRGIQRL-ESKGCNVILRYSDACDVEQMTSITEELKKVYG-HINGVVHCAGVAGDGFLFRKDMDVFNRVINPKIYGTIILDQLTRDQELDFF
ILFSSMQSLFGGPGQGDYTAANTFLDSYAPYLW-KKGLAAQTINWSGWSETGMAVDYQVNDS----NFRSLETQVAINALNNVINSNMSNVVPGK-IN-F
DVLGQIGADN---------LPFA------LS----AGLKKNLARQKSKNR---------------DM-GSNEVKQDLVILG-KS---KEYTETEKNVAYL
YAIVLDLKEIDIYENFNSVGGDSIHAMQLLKELGALYPGMVDVSDIFTHPTVEELAEFIDKK----------
>tr|K4ZHS7|K4ZHS7_PAEAL Polyketide synthase subunit OS=Paenibacillus alvei DSM 29 GN=PAV_8c00060 PE=4 SV=1
------------------------VFYGMNWMLQSATIQKTQVQGSILVFCDHGEYARALAERIQPQDRLFFVSIGKEFSQIDETHFTVG-EDEEDYDKL
LAAI---SVNLCSVYHFSTVDFTRTDVSAERYGEELHQGLYSVVYLTRALLRIRDSVDFVLLTDYAHEVTGEEAVKPAHAAFLAVTKSTAAEYPNLRYRC
IDIDEA-T----DMETVLDEVMT-DNPTFRVAYRNNQRFTEALTVIEQKQE-SIKRLEIKQTGFYFITGGTGGLGLQMAIDLGNKGAQTICLLARKALPT
LLS-DGDLIESILYL-ENLGCTILLRYADVSDMVRMESILSELKAAYG-PINGIIHCAGMAGDGFLFNKNMNTFRDVIRPKIDGTVVLDALTKGETLDFF
ILFSSMTSLLGGPGQSDYTAANAFLDAYATYLR-KKGIPALTVNWPGWSEVGMAVDYQVADA----VFRSLETEAAIQALNEIIKYDLSNVIPGQ-IN-Y
DVLQQIGENN---------LPFK------LS----AWLKKNFDRHISRHN---------------TK-KKQVAKQDVHIIG-KN---DNYTTTENEVAFR
YAIVLDLREIDIYESFNSLGGDSIHAMELLKEINAVYPRTIDITDIFTHSSVEELAGLIDKK----------
>tr|F5LIX7|F5LIX7_9BACL Phosphopantetheine attachment domain protein OS=Paenibacillus sp. HGF7 GN=HMPREF9413_5750 PE=4 SV=1
------------------------QYRTTHWIACSDPIDKAVVDDCILVMYRQGQLSS-LMLQM----RQY---FGERIIAVE------L-REACDFDTI
LSSL---AKEIKYIVHMASLIHEEMQTGSQTEMELLFKSTF--NLIKALLNQVRHSINLVIYTSNATKVTGEEEIQPLSYGLSGMVNTIGREYANIKTRV
IDIDND-T-----SADVLIEDMLSNESLHAVSYRKNVKYMQQLNNVTHGTALNDEQMTLVDNGVYIITGGLGGMGLAISQYLFRLNPIHIVLLNRTY--L
L-SEPIDKLEQVQSL-WSQGYSLDIMQVDIADYIQMDDALQQLRDAHG-AVRGIIHAAGIAGDGFIMNKTWQTYESVLRPKIAGTWVLHELTRNDPLSFF
VMCSSYVSIFGAAGQSDYVAANAFLDSFSYYRR-TLGLPSLTINWTGWRESGMAAVSGIREE----GVRFLNDEEGAAAFWHALKTKLPQVLIGD-ID-Y
KALEMEHDNL----------IIS------LF----ENS--------SNHR---------------GN-DQSHWSKDKEIVG-KSM--SDITDIERNVIYA
WSQTLGNDEVDIHAKFFESGGNSLLAAYLQKELDKFYPGIIVITDMFVYSTVVEIAQYIETK----------
>tr|W4BQD1|W4BQD1_9BACL Beta-ketoacyl synthase family protein,phosphopantetheine-containing protein OS=Paenibacillus sp. FSL R7-269 GN=C162_20681 PE=4 
------------------------NNYGRVYRPYPLPM---P-SGTVVLAGRISRTER-LLQALK--------ERGHR-------VIEIT-SDSGDWEQP
LKLL---SNELSQAIFVWD---TPGALSSQSWGEVDEAVYQGAAFLKAWSTALKTQAGVIALTHRGWSVGDDETLHPGQAALGGLWRVGALEFETMNLRC
IDQDEE-T-----SSDVMLDEFADVGRPTFLAYRKGQAYEPVVEDCAVPTQ-AALPVPV-HSGMFVLSGGTGSLGMEVAGLLARRGVKRMALLGYRTIPH
LVESSMDRLKQWLEL-ERVLEVLEVRSVRIEDFEAVAALMSELRSDHG-PIQGVIHLAGRAGSGFLFQKTEETFREVYAPKANGALNLHLVTLEDQPEIF
IQFSSISSLLLNPGQSDYTAANMFMDSLAAYRR-QMGLPALSLQWPAWRETGIAWRMNAVDE----DFTPLNTDEALALFDRIVWRGLPPVIMPG-RT-F
KTNGYIQQKP-------------------------------------------------------KM-LHNTVPQRTQITG---I--TEPDEFDLEVAGI
WARTLELDKVEADDEFSSIGGNSLLTSQMLREYEKIYPGIMEIADLFTYTTIHKQAGYVREQ----------
>tr|H0BQL8|H0BQL8_9ACTN Putative uncharacterized protein OS=Streptomyces sp. W007 GN=SPW_7556 PE=4 SV=1
------------------------GGYGYGYRRTGAPPRAGT-GGTVLLCGGFGPLGP-LTGELR--------AAGYD-------HLHVA-DA-DDDRI-
---G---EGRFAFALL-AA---VPDDDAAPLTERVIEPVDRTVALLRLLSARPELTGGLLALTRSALAVTDEEAPDPGQAGVLGLTRIAALEYRALGIRC
VDVGEG-T-----PPTVLIAEAQATGRPPLVLYRGAQPYEPVVERHPVTLR-EPASGPVPPDGVTLISGGTGGLGQAVARDLLRQGFGPVVLLGSEREGS
A-------------P-ADGPAVAEVVRLDMGDPAAVRRTVLGLRERHG-RIGGVIHLAGRPGIGFLHTKSTDEFMAVYRPKALGAIALHEATQDDDLDFF
VMFSSVSGLLLTHGQSDYTAANLVLDGLAQYRR-AQDLPALSIQWPAWRETGMAARLHAVDE----DFSPVDPAEGTRLLRA-LMTGHPAVLMPG-RR-R
AATAVTGAAG-----------------------------------------------------------RTPDTTERPVVG---L--DGAGAVEQAVAEI
WARTLDVTGLDAYDEFDHLGGNSLLTAQMLRYYDERFPGLMDITDLFRFTTIADQAMCIASR----------
>tr|J7L0S3|J7L0S3_NOCAA Short chain dehydrogenase family protein OS=Nocardiopsis alba (strain ATCC BAA-2165 / BE74) GN=B005_2046 PE=4 SV=1
------------------------GGYGHGYRKASPPVEVGT-TGTVLLCGDFGSMDD-LTDELR--------SAGHD-------HLHVA-DTAAVDRI-
---D---EGRFAFAIL-AG---VPEDDGTPLAERAVEPVERTVSLLKGLAARPELGAGLLAVTRSALAVTGEE-VDPGQAGVLGLTRIAALEYRALGIRC
VDIDEH-T-----PPKALITEARATDRPPLLFYRGERPHEPVVERHAVVPR-DETPGPTPPDGAVIISGGTGGLGAAVARDLAGQGFRNLVLLGSEGRGF
G-------------P-QDDPAVAEVLRLDMGDPEAVERTVREIRERYG-RIGGVIHLAGRPGVGFLHTKTIDEFMAVYRPKALGGIALHEATRDDDPRFF
VVFSSVSGLLPIHGQTDYTAANLVLDSLAQYRG-ARNLPALSVQWPAWREVGMAERLGAVDE----DFPPLDPAEATGLLRE-LMAGRPPVIMPG-RK-R
PAANVAEPAR-------------------------------------------------------R--ADGPGAADRPVSG---L--DHVGEIERAVAEI
WARTLDVTELDAYDEFVSLGGNSLLTSQMLKLYDERFPGLMDITDLFRFLTIADQAACVASR----------
>tr|H0KBQ2|H0KBQ2_9PSEU Beta-ketoacyl synthase OS=Saccharomonospora azurea SZMC 14600 GN=SZMC14600_22875 PE=4 SV=1
---------------------------RPVWEPAPIEESVPPEGAYLLLARTKDERARLCE-ALRAEAVVVLAEPGAEFARQAEHHFVLNTGHEDDVARL
LSELADDGVDVRAVVHALARPD--------GTGSEFDDGVGSLLPLCKALLARRGELRMVYLCP---------AGSPAHEAVAGFARSARLENPRLLCHV
VSG-ATDAASFRDA----VRELGVDATRPEQVHRRRVRGYRPMEPESGPL----TTVPLRDGGVYVITGGAGGVGLLLAEHITRQVTSTIVLTGRSEPSD
AV---SARMAALE----TRGSTVRHARVDVTDEDAVRRLVAD-LREEHGGVHGVVHAAGVLRDGFLFRKSRADLAAVLAPKVTGARVLDRATAREDLDFF
VLCSSVAAVFGNVGQTDYAYANAFLDHYASLRQELRSGRTVSIAWPHWQNGGMALSQDAQALRRRTGLTSMSTAECLAAFDDALRSSQSCV---------
----VV----------------ATG----DRDR-----IVEQLAPGGEVRPKAIAV-----------------------APEPMSDTTARRRVLDLLRDT
VGEKVGVNDVETTVPLTRYGIDSVVVTELTNALGDHFPD-LAATAFFEYETLEALADHLADE----------
>tr|A0A0K0PD94|A0A0K0PD94_9CYAN Malonyl CoA-acyl carrier protein transacylase OS=Scytonema sp. PCC 10023 PE=4 SV=1
---------------------------APSWRLEDNSPLPNLEESCLLVYPLS--CLPLADAITSSSHKCFRVQLGLASGRLGENLWEVKADDPLAWHCI
PALMEKVGSSPLTIYFLSGNQTQWGDDNLEVLEESQLQGIVSLFRLFKGIISHNFPLCLKYQ-IKS-----EEAINPLTASLQGFTSSLAREYPQLEVSC
LDIDLDDATEEKRQT--WVAPILTEPQGEVVALRRGRRTLLPINLP---SV---PKMPFRTKGVYFILGGAGGIGLELCRYLTEAVQAKVILVGRSELDA
QK---KETIRTIE----SKGGNILYLKADATDLDSMKKAVAE-ARTRYGKIHGVFHSAIILKDKTLENMDESTLRMALDIKVRGSVILHKIFHEESLDFM
LFFSSAIAFSGNAGQANYAAGCTFKDAYAHSLAKKKGFPVKVINWGYWGTVGIVASEDFNKKLAAGGLYSIQPEQGMESITRVLSHPLNQV---------
----MPI---------------NANEKNAYEEYD----KEQLRTRLSIKIVSATDHYNQCVASNVAAYTKASPVKSRSPVIQKPERARKATDLKTYIEEN
LVQALDVSDINIKKPLSDYGVDSITGVDLINRINKTLKLQLRTTALFDHANIEGFSNAILDE----------
>tr|A0A0K0PDD5|A0A0K0PDD5_9CYAN Malonyl CoA-acyl carrier protein transacylase OS=Planktothrix paucivesiculata PCC 9631 PE=4 SV=1
---------------------------APSWTIEENSSRPT-KESILLVYPLP--CLPLADALVFNNHKCLRFQLGLTTRKLGEDLWEIKADDLLAWNSI
LALREKIGSSSLTIYFLGGVYKNSENDNLEVLELSQQQGVMSLFRLFKSMISDNFHLRLKYQ-IKL-----GEAIDPYNASLHGFTSSLAREYPQLEVSC
IDINLEDVTEEKRQA--YITPILTEPQGEAVAIRQGKRKLLPINPP---SV---SKIPFRSKGVYFILGGAGGIGLELCRYLTETVQAKVILVGRSELDT
DK---KEIIRSIE----SKGGEILYLKADATDLDSMKKAVTQ-AQNRYRKIHGVFHSAIILKDKTLEKMDESSFRMALDIKVLGSVILHKIFQGEALDFM
LFFSSAIAFSGNIGQANYAAGCTFKDAYAHSLAQKQDFPVKVINWGYWGTVGIVASEDFNKKLAAAGLYSIQPEQGMESISRILSHPLNQV---------
----MSI---------------NANQKNAHEKYD----KQQLRTSLSIQIVSTTDHYNQSVARNVLAYTKADSVKLRSPLIQKPKKERKTTDLKSYIEEN
LIQALDMSDINMKKPLSEYGVDSITGVDLINRINQTLKIQLRTTALFDHANIEEFSTAILNE----------
>tr|A0A0K0PEK4|A0A0K0PEK4_9DELT Malonyl CoA-acyl carrier protein transacylase OS=Candidatus Entotheonella sp. (ex. Theonella swinhoei) PE=4 SV=1
---------------------------------------------------------------LE-GLRCIRVCIGERFRLLEPHYYQLNPRQYDDYASL
AQALRQNASWPRRVVHLWQSNEPDVN-HDQHLSLQLERGFYSLCHFTRALMQHTFACDILAW-QP----------EPACAAVSGFAHTLALEHPGFSCKT
IEIPAFLARTIDLL----LSELQ--ALSDTTVLQRWVQHFCEWQASPIEV----VSKYPRPHGVYLITGASGSLGAQFARHIAAQVKATFVLCARSERTP
AC---EQLINTL-R---TMGSEAVYIRSDLSQRDHVFKLIEE-IQARFKALHGIVHSAGVISDALVFNKTHHQIAQVLAPKVYGTVYLDEATKDIPLDFW
VLFSSTTAVTGNVGQSDYACANRFMDEFAVWREQQRSGKTLAINWPYWRDGGMSMSPGYQGWMERTGLQALPTSEGVAAWDDLLNAPSGHA---------
----YVV---------------AYG----FREL-----LSRMFARPQSAAAQ--PS-----------------------ADEATSSETLYEDTMSWLQHE
IASVVKASDIDVDTAFHQFGLDSVVMRQTNVVLEKKLGA-LPKTLLLEYTTIRDLTDHLSTQ----------
>tr|S4XKK3|S4XKK3_SORCE Uncharacterized protein OS=Sorangium cellulosum So0157-2 GN=SCE1572_03900 PE=3 SV=1
---------------------------------------------------------------GL-ARRILWVRPGARFDISAPDAIAVDPSSPDDYRQL
WAHLAGPGSAPAALVLLWPWRLSARAADAGDVERALAHGIRAIELLARAMCGAPPETRLVLE-VR-------AGDQPLGEAAAAYGRSLRPLLPQVRFLS
LMLPGDLRRLADLL----DRELSDAPHREVAY-----RGLGP--AEPIPSE---DGAALRERGHYLITGGAGGLGRIFARHLARRCQARLLLLGRSPLDE
RL---RAELTSLEE----LGAEIMYHQADVTRARDLEGALAE-AKRRFGPLHGVIHAAGVITGRLLTDKSHAEFEATLRPKIAGTPAIDAVTAGEPLDFF
VAFSSASSWLGDMGQGDYAVANRFMDAYCLHREGLRRGRSVSIAWPLWRDGGMRFADLEQRYLRSSGLTLVEERHGIEAFEAILAGGPVQV---------
----MP----------------LVG----DLSL-----LAPIL---GLSAPRAKPSFNAAAVD---------GVAREAPAGGGGAAGPAREQIEADLRKS
IAAHFKVNELELDDHLGALGFDSLMLTELADRMSRRYGVEVLPTVFFSHNTVRSLAAHLVEA----------
>tr|A0A060DS91|A0A060DS91_AZOBR Uncharacterized protein OS=Azospirillum brasilense GN=ABAZ39_27230 PE=4 SV=1
---------------------------------------------------------------LA-LGPALLVTPGTALRHG-GGRAEIDPADAAHYRSL
IQDAVSRGAGPAAIVVAWAGRLPTD--PAV-------QGIHAVRHILRAVIDAGHLVRLLED-SAD-----AAAAAAVFDAVAAYAPSVKPLLPNLGVTC
LRVDPSIAALAARL----CGELA--PEPEVAYVVRRVRVLGPVSTALAPSG---DGVAIRAGGVYLITGGAGALGRIMARHLAARGAGQVVLVGRSAPEA
---------VSLEE---LAGPVFSYRQADVTDAASLGAAVAE-VLERFGALHGVIHAAGAFTGRPLTAKTPEEFAATLAPKLDGTVALDRATADLPLDFF
AVFSSVSAELGDFGQCDYAVANRFQSAWGLWREGRRQGRTLSIGWPLWRDGGMHTEAAEELYLRTAGLAALESAEGAELFDRILRSGRSNV---------
----LL----------------LKG----EPER-----AARLFATRGIAGPRRAAAASLVA--------------SALPPTAAADGAPIADRLRRDILHG
IAQSASVPTVERAGHLGDLGLDSLMLSDLADRLNAGLGIALSPTTFFSHGDLDSLTSHILAE----------
>tr|A1KQR7|A1KQR7_9BURK RhiB protein OS=Burkholderia rhizoxinica GN=rhiB PE=4 SV=1
---------------------------VEKWQR--FQDLVPSTGRLLLISNDPQGHKQLIARYPQ--------------------AGSLLLDGHESIEQL
TERLREVGPI---EHLIWLAPATLAQENLDGMIRAQQHGVLSCFRLIKALLALALQPLTWVLTVSNEADAVTGPVAPAHASVHGLIGVMAKEYSHWRVRL
VDLPVGDVDPLSLP-----------PRGDALVCRDDVWYLAPYLPLSKWGD---VDSLYRDEGVYLVIGGAGGIGRLWSEYLIRTRRAQIIWLGRREQNS
DI---DQAIAELA----KLGPAPRYLRADASNHAALRQAVAQ-VYTEYGRIHGVVHAAIQLQDQSLARMDEQRFTTGLAAKVDVCVRLAEMFAHQPLDFM
LFFSSLQSFTKSAGQSNYAAGCTFKNAFGHYLAQQCSYPVKVINWGYWGHVGSVASEDYRRRMAEVGLGSIEGEQAMAALDMLLAGPLSQL---------
----TFL---------------RTSQRSSEHEI-----IEQMKQRSGLHCPTAYDFFNEVMLNAMVEFAPKRLAVQAAPASREVTPQALKDQTVHYLKQM
IGGLFKIRQIDAGEPLETYGIDSILVVQLTNLLRDKLSG-ISSTLFFEYQTIDALADHFVES----------
>tr|D8P4C8|D8P4C8_RALSL Polyketide synthase, rhizoxin biosynthesis OS=Ralstonia solanacearum CFBP2957 GN=rhiB PE=4 SV=1
---------------------------VEKWRRSSFQDLTPPDGRLLLIGNDPEGHRQLTTRYPQ--------------------AVALLLDGSESVEQL
IEQLRGAGPA---EHLVWLAPAAPVRADVGGMVRAQQGGVLACFRLIKALLALAFRPLAWAQAVFGDAGAMAEPVSPAHAGVHGLIGAMAKEYRHWRVRL
VDLPAGDLNLLSLP-----------PHGDALACRNDVWYLAPCLPPPGPGA---ADSLYRDRGVYLVIGGAGGIGRLWSEHLIRTRRAQVIWLGRREQNS
QI---DAAIAELA----RLGPAPRYIRADAGNHAALSEAVAQ-VCAEYGTIHGVVHAAIQLQDQSLARMDQQRFAAGLAAKVDVCVRLAEVFEHQPLDFM
LFFSSLQCFTKSAGQSNYAAGCTFKNAFAHYLAQQRAYPVKVINWGYWGHVGSVASEDYRRRMGEAGLGSIEGEPAMAALETLLGGPLAQL---------
----TFL---------------RASRRGREREV-----IAEMKQRSGLARPVAYDFFNDVMLDAMVEFVKVAPKAPAVPASREVTRAVLKDQAVRYLKEV
VGGLFKIRQIDAREPLETYGIDSILVVQLTNLLRDKLSG-ISSTLFFEYQTIDALADHLVAS----------
>tr|K9EIF2|K9EIF2_9CYAN KR domain-containig protein OS=Leptolyngbya sp. PCC 7375 GN=Lepto7375DRAFT_0419 PE=4 SV=1
------------------------------------------NAAIAIIGGTPEQLRAIHKNYPA----------------------PLQL---PNTADL
KQWSAVLDRLPELDHILWIAPETEPLLVDDRVIEAQDIGVIQVFRLVKALLSLGYKTLGWAQAVLQ-----TEPIHPIHAGIHGFVGSMAKEFPQWQVRL
LDLDAQPALWTIP------------PQGEALAYRGNQWALIPVQDL---AV---NPEPFRTQGTYIIIGGAGGLGEVLSRHLIQHWQAQVIWVGRRPLNL
DI---QTKIDALA----ALGAAPWYLSADAANVSDLERVRNA-VQQKCGSIHGVVHSALGSYDQSLTAMDEAQFRSVLSAKVDITVRVAQVFAEEPLDFI
LFFSSLASFGKVRGMSSYVAGCVFQDAFALRLSQICSIPVKVINWGFWSIGGGARITLRRHLQETEGVQPINADVGMGVLAQCISSNISPL---------
----AFI---------------KSDASNGVIEN-----SATLRQRTGVTITVEDHFFNTALAEVAAAWIASPGVERGQPPES---HTVPTVDKSAYVQQC
LSRTLRLDRFELDVSFSDYGVDSILGAQFITLVSAALDIDLNTTIIFNYPTVERLSAHVVEA----------
>tr|A0A0G8EZ61|A0A0G8EZ61_BACCE Uncharacterized protein OS=Bacillus cereus GN=B4077_3540 PE=4 SV=1
--------------------NISEWFYTPQWKSSTLFEPNHDVNETWIVFVDQEGLGNEVKDLLNKGQRVVTVEPGFGFNKENNDRFIINPEERTDYVKL
LDEVQEICGLPTKVVHMWGITDEERQASIEYVNCKQNLGFYSIFYLTQALGDKSDSISIRIITNGVQQVIGDEELIPEKSTVLGTSLVVPQEYSYLSCSS
VDVVIPLNKELKRLINQLVEECLSNTNDKMIAYRGNKRFVQTYEPLQLEQPAKEKLPL-RKNGVYLITGGLGGIGTILAKHLAQTVQANLVLLTRTGLPN
YSD----RIRKVLE-IEETGSKVYVLAADVTDQSQLYEAIHKAEQKFGK-INGVIHGAGILGGNLIQELEKEDCEEQFSAKIYGLLNLEECLRNKDLDFC
VLMSSISAVLGGLGYVSYAASNIYMDVFAQYINRYSNLPWISVNWSDWKEKDMQIGA----SVHE---LSMTPEEGIQAFNIALS-------------WK
QGEVLIHSPGELQADQWVLNSFNDE----KEEEL--------DSTLYHSRP--------------------------QLL---TEYVAPRNEVEEKLSKI
WRNIFKVSEVGVHDDLLELGGDSLKAITIVSKIHKEFNVEVPIKELFTLSNIEKLANYISRADK--------
>tr|L7UIH3|L7UIH3_MYXSD Non-ribosomal peptide synthetase OS=Myxococcus stipitatus (strain DSM 14675 / JCM 12634 / Mx s8) GN=MYSTI_04971 PE=4 SV=1
---------------------GRDWTYEVSWEPRPLAPAGTARPETWLVFTDEGGVGVSLASLEAGGARCVWVRPGAAYSSQGGSAFTVDPARADDFARL
FREVAGPGPACRGAVFLWGLDARAE-----------VPACQGALLLAQELARAVVSPRLWMVTRGVQCTGHESVPAVLNAELWGLGRAMALEHPDSWGGL
IDLDAVAD---AREPELLMAELRQSPEGEQVAYREGQRWVARLTRCPVSNPARPPGARVHPEASYLITGGLGALGLHVARWLVDQGARHLVLMGRSAVGE
AAR---DEVRSL----AQAGASVDCVQGDVSHPEDVSRIL-GAIAASGYPLRGVVHAAGVVEDATLLSLDWKRFERVLAPKQQGSWNLHQQTKSLPLDFF
VLFSSSSAVLGAAGQSNYAAANAFMDALAHHRQ-ALGLPAVSINWGPWSGAGMAASLE--VPEQRRWFDWIDPAQGLELLGQVLDSGRTQVAVPVDWSRY
ARR------------------Q-------------------------SESGAVGLLRNVLDDARVSLPRVVPMWERLKGQ--------QRNRQETLFDHI
HQQVAQVLQMSGGLGLFDAGLDSLLAIELRNRLQTSLGRPLAATLVFEHPSIDSLTEHLATE----------
>tr|Q70P96|Q70P96_9DELT MelD protein OS=Melittangium lichenicola GN=melD PE=4 SV=1
---------------------GSQWTHEVRWEAQPHDAGEAVLEGTWLVLADATGTGDALVSLRGRGVRCVVARPGAAYAAHDGQTFTLDPSRMEDFSRL
LRDASAPGPPCRGIVHLWGLEPDAPVT-LASLREAQRLGCESVLHLTQALVRFPVRPRMFLVTRGTQRTGQETPPALAQSALWGLGRTLALEHPEFSPAL
VDLDSRAP---STEDASLIAELLHVPRGEQVAYRQGQRYVARLARYAGSD-ARSAASRLRPDGAYLITGGLGGLGLQVARWMVERGARHLVLMGRKEPGE
AAK---ESLRAL----RQAGAEVTLASGDVSQPGDVARVL-ASLAQTKTALRGVMHLAGVVDDGTLLHQNASRFERVLAPKQAGGWNLHEQTRGMDLDLF
VLFSSSASLLGAAGQGNYAAANAFLDALAHHRR-ALGLKAVSINWGAWSGHGMAAAFA--SPEQQRGSEWIDPERGLEALGQAMEEGPAAVAVPVDWNQY
VQR------------------F-------------------------AS--SANFLRKLIEPGRVGTPGEATLVDRLKGL--------PRGRQEVLLDHV
HQQVHQVLALAGNDRLFDAGMDSLMAIELRGRFQSSLGRTLAATLVFDHPTIDALTHHLATE----------
>tr|Q5MD34|Q5MD34_9DELT CtaD OS=Cystobacter fuscus GN=ctaD PE=4 SV=1
---------------------NSQWTHEVRWESQPREAGETVLEGTWLVLADSTGTGDALVSLRAKGARCVVARPGPTYVAQDEQTFTLNPERVEDFTRL
LQDASAPHPPCRGIVHLWGLEKDAPVS-LASMREAQRLGCESVLHLTQALVKLTVFPRLWLVTRGTQRTGQETPPSLAQATLWGLGRTLALEHPEFSPTL
VDLDPSEP---STEDASLLAELHQAPRGEQLAYRQGQRHVARLARYEGAD-TRSTAPRFHPEGAYLLTGGLGGLGLQVARWMVERGARHLVLMGRKEPNE
AAR---ESLRAL----RQAGAEVTLASGDVSQPGDVARML-ASLAQTKTALRGVMHLAGVVEDGTLLNQEASRFERVLAPKQAGGWNLHEQTRDMDLDFF
VLFSSSASLLGAMGQGNYAAANAFLDTLAQHRR-ALGLKAVSINWGAWSGHGMAAALY--SPEQQRGAEWIDLERGLEALGQALEQGPATVAVPVDWNRY
VQR------------------F-------------------------AS--AASFLRKLIDPARTGAPGETPLAERIKGL--------PRGKQEALLELV
HQQVHQVLALAGSDRLFDAGMDSLMAVELRSRFQSNLGRPISSTLVFDHPTIDSLTQYLATE----------
>tr|Q9RFK8|Q9RFK8_STIAU MtaD OS=Stigmatella aurantiaca GN=mtaD PE=4 SV=1
---------------------GREWTYDVSWEQRPRSGIDAVLEGTWWVLADSAGVGTRLVALQSHGARCVVVRPGPAYEARADRTFVLNPARVEDFERL
LVDSQGPALPCRGILHLWGLDEAP------SLEAAQELGCRSVLNLAQALGKLEVSPRLWIATRGTQRTGHEQPPSLTHAALWGLGRTLAVEHPELSVAL
LDLDERAH---ASEDSLLIEEFLLDPDGEQVAFRNGRRYVSRLARCAVPN-TQPSATRLREDVSYLLTGGLGAIGLHVARWMVERGARHLVMMGRTEAGS
AAQ---EALQSL----REAGARIRLEQGDVSQPGDVARVL-ASLAQSGPPLRGVMHLAGVVEDSMLQQQDWPRFKRVLAPKLQGSWNLHHQTKEMDLDFF
VLFSSSSALLGAAGQGNYAAANAFLDSLAHHRR-ALGLKAVSINWGPWSGGGMAASFA--GSEQRRWVDWIEPAQGLELLGWALDAAQAQVAVPVDWAKY
FQR------------------F-------------------------GDTGATKFLSRLLEETRSGTAKQPKLLERLKGL--------TRNRQDVLLEYV
YSQVTQVLPLAGNQRLFEIGMDSLLAVELRNRFQSTLGRPLSSTLVFDHPTVEALTGYLAAE----------
>tr|G4RJD0|G4RJD0_CHOCO Non-ribosomal peptide synthetase/polyketide synthase OS=Chondromyces crocatus GN=croI PE=4 SV=1
---------------------PATPLHRIAWEPAPAVAPGMVSSGPCWIFADEGNAGSSLRHLERTGVHCHLIRRGERLDTPGPGIHTLDPDQPEQLDQL
LDTL--AQGKPRGIVILWPLDESPGDPGMGGALAATQRLCSRALTLVQKLAPSAGDGRLWLVTRGAQTVGTNAPVSPTQAALWGFGRVLASEHPEFQSGL
IDLDPESS---ADEASHLAAALLASTDEDQIALRGGRAHHA--RPQPDT-LPVSGRRPVLGGGVHLITGGLGGLGLLLGRWLAHAGAETIVLMSRSTPGP
EAI---RALDEL----KTGPARVRVMQVDVSRADALSAAL-DTLRREEGPLRGIFHLAGSLSDAVLLRQDPERLHAVLAPKVAGASLLHALTLHDPLEHF
VLFSSIAAVLGTPGQANYAAANAFLDGLAQHRR-ALGRPALSIQWGPWAGAGMAAEQG----AADRGFESMPPEQALALLERLLGGAAGDIGVRVDWRLL
LAR------------------L-------------------------PTVP--PLLVEQLPAEARTARAAAGPPAWIRSL--------EPEDEGLLRARL
LDLVRQSLPIDPRMPLHELGLDSLMAVDLREAIGKSVGLRFPATLLFNHPSIEALVAFLRRE----------
>tr|C5ANC8|C5ANC8_BURGB Short-chain dehydrogenase/reductase SDR OS=Burkholderia glumae (strain BGR1) GN=bglu_2p0590 PE=4 SV=1
---------------------GTDRLFAPRWQRLDDLVI-PLPADDCLIAGDGAGAGAALARLRGVGVRCLRIDAASHTSDELT-VALADPASEAAWRDT
LRAAAARAQGTLQVVDLRALDLGVGAEVPADALAVQAQLCGGALALVGALTQVDRPVRVNFITRGAQEPGGTNVERAAQATLIGLARVVAAEHPEWGCRT
IDLDPATA---DP-AAALAPLLHAAPDELQLAIRDGAVHAARLKPARRD------APSLESNGSYLITGGLGGLGLRLAQQLAKAGVKRLVLMSRGAPDA
AAT---TAIDAL----RQLGCTVDLARCDVADPAAMRLAWHETVLSGPFPLKGIFHAAGALRDGVLGGQSWAEFAVPLHAKVAGALNLHALSLDAPLDCF
VCFSSISALFGTAGQANYAAANAYLDALVGARR-TLGLPATSIQWGPFAEVGMAASLD--RAHRDKGLQLLAPDELLKHIEAARRADVATVVINDDWQRY
AQT------------------E-------------------------PSEGVRKLLADWLPTEAADTAR-HDERDRFDAL---------PALRDALAIYL
QAQIAVMLEVAPTRGFLELGLDSLAAVEFRSKVQRDLRLSLPATFAFDYGNVELGADFLFER----------
>tr|F4XMC8|F4XMC8_9CYAN Amino acid adenylation domain protein OS=Moorea producens 3L GN=LYNGBM3L_21990 PE=4 SV=1
---------------------LENCLYQVEWRIKELQSS---KPKNWLIFTNSQGVGQQLVLLQSQDQGCTVVFPGKEYEQIAEHKFRIDPANPQHYQQL
WEKI----SNIDGVVHLWSLDSS-L-----DLELASRISCGSTLYLIQTLLKGKPP-RLWFATRGAQAVGANAVPGVAQSPLWGMGKVIGLEYPEFNSVL
VDLDPNPA---VDEIQTLWAEIQSEDKEDQVAFRNQARYVARLVSRSPV-VETNKPLVFHNDRSYLITGGLGDLGLLVAQWMVEQGAKNLVLVGRSSPKP
AIE---HKLRKL----ENLGARVVVAQADVSNAGQVTELL-TKIEQSSFPLGGIVHCAGVVEFSGLSQQDWQRFAQVLVAKVQGTWNLHALTQNQPLDFF
VCFSSISSLLGSHGLGSYGAANAFLDSIAAHRQ-ALGLPALTVNWGPWGEIGMGAKLS--TDHQGRGLANVAPKQGLFALEQLLQQDLAQVGVSVDWQKW
LRQ------------------F-------------------------HSLP--PFYEDVAPNTTVNTTVNLDFKTELEAV--------PANQRDLLVERV
RTQIAKTLQIELGQRLIDLGLDSLMAVELRNHLQSSVGCSLRSTLVFDYPTIEAMVDYLSQE----------
>tr|F4Y2Q3|F4Y2Q3_9CYAN Polyketide synthase module OS=Moorea producens 3L GN=LYNGBM3L_69620 PE=4 SV=1
---------------------IADWFYIPSWKRSIPPAYEKLLESDTLVFIDECGLGEKLAKLAIQGSDVVRVSRGSEFAKQSDRVYTINPTQADDYHTL
LQELKQ-LKNPSSIIHLWSVTPNNHTEGIESFEASQDLGLYSLIFLAQALDKLIDPLQLTVVSNNLQEVSGEEVLSPEKATLLGACKVIGQEYPNINCRS
IDIVLPPS---QKQLTQLLAEITAQSEDLTIAYRGKHRWVQKFEPMGLE-TPGAETLPLTEEGVYLIIGGLGAIGLSLGLHLAKTVRAKLILIGRSQFPS
RKI---QKLQAM----EAMGAEVMVLSADVADGQQMEAVV-AQAEARFGNINGVIHSVMFTGDKATKTDIWQHF----QGKVQGTIVLSKVLHNKNLDFC
ILMSSIASVLGGLGDVAYSAANLFMDVFVHQNR-SNSVPWLSVNWETWEFEKQDQNY-------EIAEFAITPEEGIQAFERVLSTQELNIGDQARIDRW
VK-----------------------------------------------------LKSVKQQNNSHNQVPVTFRKQLETV--------PVGEQGLLLTHV
RAQVAKVLRITLEQKLIDLGLDSLMSIELRNALQLSLGFSVPSTLLFDYPTPEALTSYLAQE----------
>tr|B1GYG6|B1GYG6_CHOCO Hybrid polyketide synthase/nonribosomal polypetide synthetase OS=Chondromyces crocatus GN=ajuL PE=4 SV=1
--------------------------HETVWREHHPSADSIRAPARWLLLADEGGVGEALARLRARGSHVVIARRGAQCSEESPGLWTVAPDRPEDLVEL
LTRAFPAGGGPGAVVYLWTLDAPALSGDAT-PEAAEPLTCGSLLLLTQTLARHDLGPRLWLVTRGAQPVEAGAPVAAQQAPALGIGWTLALEHRTLWGGA
IDLDPRAP---DGEIEALCDALCAPGGEDRIALRSTPDRGLRRVPR--A-FDSVPAWRPQRGSTYLVTGGLGGLGLRLARWLVERGARSLVLMGRSAPSP
AAS---EILSTL----RERGAHVEIAQGDVARAEDVTCTL-SIIAHHASPLGGVFHAAGVLDDGMLVGQDPARFHRVLAPKVQGAWNLHVATRDLPLDSF
VLFSSGASLLGSAGQSSYAAANAFLDALAHQRR-AEDLPALSVHWGPWAEAGMAASLT--QQDLERGVGLIPPAEGLALLGELLGGAPPEVAVPMDWNKA
SET------------------F-------------------------GRTG--RLLSELTRA-------PVKMRSWLDPL--------P--EHDALLTHL
QRRIADLLLPEANQGLFGMGLDSMMTLELRSRLELEASQPMPATLLFTYPTIDALTRYLLGE----------
>tr|L8LXN2|L8LXN2_9CYAN Amino acid adenylation enzyme/thioester reductase family protein OS=Xenococcus sp. PCC 7305 GN=Xen7305DRAFT_00005970 PE=4 SV=1
---------------------LENALYQIEWQPKKLDSTANTNTQNWLILADTQGIGEKLAKLQAQNQSCTLVFPAQEYQQVEANEFHIDPYNPQHFQQL
VTDL----PAPNRIIHLWSIDIAKPEL-TEDISQSSQLGCGSTLHLVQALLGNDPP-SLWLVTQGTQAVAKY-VTGIAQSPLWGLGKAIAAEHPELNCVR
LDLDPQEK---EDAVKILWSEIQAQDIEDQIAWRNNIRYVSRLKRHSKS-ATNGESLTIKQDSTYLIAGGLGDIGLKVANWLVDKGATHLVLLGRSHPKS
TAI---TQLDKL----QQLGVKVIVTQADIANHEQVDSVF-KQIKKTLPPLKGIIQAAGTTDDGIVRNLTWDKFAKVLAPKVQGSWNLHTCSAACDLDFF
VVFSSIASLLGSAGHSNYVAANSFLDSFAAYRR-SQGLSALAINWAVWANIGLASRNL---QVLDRGIGSITAKQGLQILDRLLQEQPTQVGFPIDWSLF
SEE------------------S-------------------------WSDA--NFFKDLKQES-ARSLISLTFRQQLAKT--------TVENQKLLSNHV
CTLIAKTLKLDISARLIDWGLDSLMSIELRNHLQSSLSCSLRSTLFFDYPTTETLLEYLASQ----------
>tr|E3FL92|E3FL92_STIAD Modular polyketide synthase OS=Stigmatella aurantiaca (strain DW4/3-1) GN=STAUR_4014 PE=4 SV=1
--------------------DLSEKLFQVRWQSMPLAPAVPE-RGPWLLVADRGPAGEELAALKREGQVCHVLAAPESAVTGEA------------LLQR
VEEALA-LEAYRGVVYLSALEAEQE--SPQGKSQAALEGVSGAVQVLQAIAKLERGPRLWLVTRGAQALESPRPLALAQAPLWGLGLAVRDEHPELRCTL
IDLDPDPAADG---VGCLFQELLTPDREDRIAWRGGARFAQRLSFLEAVPEP--GTAPISPDGTYLITGGLGGIGLRCARWLVDAGARHLALLGRSGPSE
---AARSVLGALE----AEGVTVRVLQADVAVREDVSKVLSALRV-DMPPLRGVLHAAGLLDDALLVRQDRDRIQRVLQPKVAGALNLDLETRGDPLDFF
VLFSSIAAMLGGEGQGNYSAANAFLDALAFARR-AQGLPAHSLAWGPWAEVGMVAARSESAHLAALGIESIPPDEGVAILGRLLRAASAHVGIFIDWTRW
------------------QQRHA-EGHAPLLAGILKQQAAA----P--------SQ------DS-SEE-APDI-QELIRA----TPEERQKRAEAFLRRE
VTRILDLPLADGRLPLVRFGFDSLMSLKLKARLESTLGLSISAAKLLSGLSLDKLVALVLER----------
>tr|A0A059KPH2|A0A059KPH2_9BURK Uncharacterized protein OS=Sphaerotilus natans subsp. natans DSM 6575 GN=X805_09770 PE=4 SV=1
--------------------PWQDWLHRVDWSRDAFGTALPAPASDWAAQ--GGGAYETCVALETLAGQVLAAWRQAGVAFEPGARWTVAVPAHRRLTGR
LLEILGELGWDEGTGTDWTVRAVPA--EP-------LRRCGDLLDVLQGRVEGDTRHRLYAESPIHRLMEGLRLLEVGG-GTGGTTVGVLPRLPAQRCDT
LDIERSPLEQGF--ARGQADV----------VLAANVLHATRDL----SVGT--EALRCEAQATYLITGGLGGLGLATADRLVARGARHLLLLGRRAPDA
---AAQARLAALA----AQGVEVRVAAGDVADGAALAALLASIDP-RW-PLRGVVHAVGVLDDRPVLHQDGASLDRVLGPKVRGAWNLHRLTQGMRLDFF
VMYAAAAGLLGNRGQANHAAANTALDALAAHRR-ALGLPALAIDWGAWADIGAAAQLMRGAELVSRGLTAMAPEQALAALEALMATGARAPAHLIDWATY
------------------LRSSGEVGRLPYFAALAALQPPG----T--------PAGSSPGAGATTTAAPVPLRQQLAEV----RGAERAEILTGWLQQA
VADTLRLTLPDSHTGFSDLGMDSLMTIELRRHLSRALELPLPSTIAFEYPSVAQLRDHLLAE----------
>tr|Q3LRL4|Q3LRL4_9DELT MmxC (Fragment) OS=Cystobacter fuscus GN=mmxC PE=4 SV=1
--------------------GQRDALYEIGWKR-QPLGGVPA-SGRWLVFTDGSGTAEALAELRWSGCRPVLVHPGEAFVRHDGEHFTLDAQRAEDYARL
LAEAVPPGESLGGVVHLWAMRG-------ESLHAAHLLGCASALHLAKAL--VGAAARLWLVTRGARTLSGSAPLALEQVPLWGLGAVFSQEHPDQCGAL
IDLEPTASEQD---ALAIWRELGATDGERQVMIREG------------EPRD--AMPRLRPDASYLLTGGLGGLGLSLARWMVEQGARNLVLIGRGGPRP
---EAQEALRALE----TAGARILVLQADVSKREEVRRVLEE-AG-RLAPVRGVVHAAGVLDDGVLLQQDWERFARVLAPKVDGAWHLHELTRERELDFF
VLFSSAATLLGAPGQGSYAAANAFLDALAHHRR-ALGLPALSINWGPWAEVGMAARL--ASHFQAQGIEAFSPDVGLRMFGRALAHGQPQLTLLVQWSRY
------------------LAQYPRGAAPTLLAELSGRAVAE----P--------EA------SE---QPSAEFRRRIESAE----PRQRLSLLMEHVRGE
AARVLGLDPLESRQRLFEVGMDSLMALDLRKRLQNSVGAALPSTLVFDYPTTEALASYLHDE----------
>tr|A4D934|A4D934_9NOSO CrpB OS=Nostoc sp. ATCC 53789 GN=crpB PE=4 SV=1
--------------------KFNNWLYQIHWQTQSISIDLTK-SGSWLLFSPPTGIGKHLVELEQQGWHCILVTPGENYQQLESQHYQINPNHPEEFLHL
LQSSLEQQPPLRGIIHLWSLDSTIA--L-QELQKSQELGCGSVLHLVQALVKNQDMAPLWLVTQGSQSVGESLPIQFQQTPLWGLGRVIAQEHRELQCRC
LDLDPTMEDSQT--VAALLEELLSPGDENQIAYCQGVRHVARLERQQKEYKS--LDNLIQAEASYLITGGLGALGLKTAEWMVQQGVKYLVLTGRRQPSA
---KAQQTIEQLQ----KAGAQVLVLCGDISQQENVARIIESIKV-SLPALRGIIHAAGILDDGLLLNMNWEKFTQVMAPKVQGAWHLHNLTQNLPLDFF
VCFSSMASILGSPGQGNYAAANAFMDGLAHHRR-GMGLPGLSINWGPWAQEGMAANLDSQDRMVSKGMTFLSSEQGLQVLGQLLEQSIPQVGVLIQWSVF
------------------QEQFSFGNQIPLLSQLVKESKSQ----Q--------KA------LK-TKTKHNEFLEQLKAA----LPREREKLLIIYIKDE
ISQVLSLSQIDMQQPLNTMGLDSLMAVELHNRLQTDLLVDISIVKFIEDISIVDLATEVNEQ----------
>tr|A0A0B5ET01|A0A0B5ET01_9ACTN Modular polyketide synthase OS=Streptomyces albus GN=SLNWT_0891 PE=4 SV=1
--------------------GDAETLNRTVWAQAGLFLFRLVEVEVAAVNGPRASVLSGDADAEAVGHRIKRLAVSHAFDLCSPAYWVRHQDCLPTDTGA
EP-HGSAAPPQDRFVLL------------RALTEAVAGGPVAVLACPASATLDEVGGRLWCLTRGAVSVSSGEVPDPVLAQVWGFGRVVALERPQTWGGL
VDLPRDGKGG---------------------------------------------ADWRMPSGPVLVTGGTGALGAGVARWLAGRGAEHLVLAGRRGASA
P--GAEELVRELE----ALGVRVDVVACDVSDRGSVAALLA------EFVFSAVFHVAGVVDDGVVGSLSAERFAGVWGPKAGGAELLDELTRGMDLSAF
VVFSSFAGAVGGAGQGNYAAANAQVDALVERRR-AEGLPALSLAWGPWADGGMAVDE--VERMRLAGMTPLRQDTAFGVLDRALAADLTTATVVIDWERF
------------------APGFTSARPSPL---------------L--------AALPEVAAGQRGGPEAEPLTARLAGL----SPAERHEALLDLVGTH
AAAVLGHGGIDAEGAFKDLGFDSLTAVELRNRLGAATGLALSATLVFDHPTPNALAAHLLGK----------
>tr|S4XS92|S4XS92_SORCE Uncharacterized protein OS=Sorangium cellulosum So0157-2 GN=SCE1572_16945 PE=4 SV=1
--------------------GAGELLYRLEWRRKDLEGGGKP-RGAWLVLSDRGGTGAALSALERRGESAVRVLAAERYERVEPRRYRLDPSDASGYAAL
LADAFSEEQPCRGVVHLFGLDATAP--E-ETLLEDQRLGSLSALLLSKALVGRGFRPRLYLVTRGAQSAGEAQSVRVSQAPLWGAGRAVGAEHPELGCTR
VDLEEGAPEHG---VEALVDELVAREREPEVALRGSGRYVARLVRGPAGVEG--SGVRLRPDGSYLITGGLGGLGLSVGRWMVERGARHVVLVGCSGPTE
---QARAAMREME----SAGAQVLAVQADVSQRASVARLLSELGQ-RLPALRGVVHAAGVAVDSTVEEETEERLLRALAPKVQGAWNLHSLLSSPPLDFF
VLYSSTMSVLGPPGSVNYAAADAFLDALAHHRR-AQGLAATSIGWGLFSDVGAAARAGVAERLASRGMPGLTEAQGAEVLARMLAGGEAHALAMRHWIEF
------------------YPSAA---TSPLWEELRNERVEA----A---------P------GA---GRAAELRKALEAM----RPEDRPAALQQLVREQ
AALVLRLDRIERDTPFMSLGFDSLMGLELRNRLEAGLSVALPATLVWTYPHIAALSTYLLGK----------
>tr|D9W5P0|D9W5P0_9ACTN Modular polyketide synthase OS=Streptomyces sp. C GN=SSNG_07470 PE=4 SV=1
--------------------GATDGLFRLDWTELPAG-----AAGNWAVLGSDPAGIAAAL-----------------------EGAGAAVDRYEDLAA-
-L-AAADGTA--QTVVL---------------------------------------SRLVVLTHGAVATRGEDATGLAHSPAWGLIRSAQAENPGRLL-I
ADLDTTAESAAA--LRGAVA--ALVHDEPQTALRAGTALAPRLVRAGS-------PQGWDPDGTVLITGGTGTLGALLAKHLVHHGVRHLLLAGRRGPDA
P--GAAELVAQIA----DLGGTAEVVACDAADRDALAALLAAIP--ADRPLTGVVHAAGVVDDGVFASLTPARMERAMRPKTDAAWNLHELTRDLDLSRF
VLYSSAAGVTGNSGQANYAAANTYLDALAHHRR-AQGLPATSLAWGMWHQTSELTAGDDLARFSRGGVTPLTAEQGLALFDAAVDQDEALSVPVLDPAAL
------------------RDSAGGAGLPALYRSLVRTPVRR----A--------AGA----AAAAEPDG-SALLRKLAGL----SAERRRGVLLDLVRTN
VAAVLGHSSVEADRAFKELGFDSLTAVELRNRLGAATGLRLPATIVFDHPTPVELADHLRDE----------
>tr|D0LQW0|D0LQW0_HALO1 Acyl transferase OS=Haliangium ochraceum (strain DSM 14365 / JCM 11303 / SMP-2) GN=Hoch_2954 PE=4 SV=1
---------------------RQDGLLRVDWSDPRAF-----AAQEWALVGPEDASLISHAN----------------------SLTH-----HQDLNAL
LE-SIERGGA--EVVVVPSYDVA---------------------------------ARLIVVTRGAIATRDEDVLGLAQASLWGLVRVAQSEHPDASLTL
VDVDNREDSLHA--LFGLFGAPNALAAEPQLAVRAGNVSVPR-------------ARPFDPAGTLLITGGTGTLGRLLARHVVKHGARHLLLASRQGLAA
P--GASELVSDLA----EAGAEATVVACDVSDRSALQRLVAAVP--ANHPLTGVLHLAGVLDDAVIESLTPKHFDTVLRVKLDAAYHLHELTLEHDLAAF
VMFSSLSGVLGSAGQANYAAANTFLDALAHHRK-AQGRHGLAIDWGYWEDRSALTAHTALQRFARSGLRPLSAQEGLALFDAALTRPDAVLVAVLDAMAL
------------------AKH--ANALPPLLSGLVPAKVAR----P--------MAST--GT------SVASLQQRLASL----VVEERAPALLEIVCSE
VATVLGLAALDPERPLQELGLDSLMALEIRNRLSAATGLRLRATLLFDHPTAAALTQALLGW----------
>tr|A0ZEC2|A0ZEC2_NODSP Malonyl CoA-acyl carrier protein transacylase OS=Nodularia spumigena CCY9414 GN=NSP_42160 PE=4 SV=1
--------------------KAKNCFYQSQWKQLNSIITVKS-EKSWLVFVHPGAGLHQVINLQQAGERVITVELGDGYKCRSQDDFVINFEQKSDFHRL
YQEAYPAGEFPTGVIFT------------TEYADPVYKSFHSALHLIQTVT-THWQPDLWLVTRGANKIL-ENSLQPQQSLLWGLGAVINNEYPQMRCVC
LDLSPTAEPDE---GEFLFKELHTPSNELRLALRQGNRYGARLVSATI-PAQ--KQQLVSQEGAYLITGGLGKLGLLLAQWLSEMGASHLVLCSRNLKSP
P--EAI---TSLA----KNGTQITVICADIASPTDIEEIFARFGQ-DLPPLRGVIHAAGVLDDGLLSNQNWQRYQNVMRPKVEGTLLLDRYTRDLSLDFF
VTFSSAAVVLGSPGQSNYAAANTFMDALMQQRQ-SLGLPGISINWGAWDTENEI-----KKRLAGWGIESMSAQTGFKYLSQLILANVSQSVIIIDWANF
------------------QAAFNL--NQMFFAEVIQPKEQQ----E---------------------KISAKILEKLNSV----YIDERTAVLTKEIEHV
LRELTGLAIIPQKTSFLDLGLNSLMVLEFKNSLERELGCNLPSSVIFDYPNLTELITYLQVE----------
>tr|A0A0M4KKD6|A0A0M4KKD6_9DELT Polyketide synthase OS=Nannocystis sp. MB1016 GN=ncyB PE=4 SV=1
--------------------PSDEWFLEQAWEAVA--PAKPG-RGRFLLLGAGGGLGAALRGLEAAGHAVVHA-VAGAPGAVPAGCWAFDDGHPAGLRAL
LADVFQGTG-PTAVVHLRSLEGDDE--VADEVAEALARGCDSALHTVQALVGVESRARLWLVTRGAQAVV--APADVGQAPLLGLARVVAMEHPELRCAR
VDLDPARPGDE---AALLVKELLADAAEDEVAWRGATRQVLRLVRRAPGRSP--STWAPRADGSYVITGGLGGLGLATAAWLVERGARHLVLIGRAGVTS
A--EQREAVAALE----LRGAQVTVARADIAVREQVARVLAEV----TAPLAGVVHAAGVLDDGLLLQQDRRRLRAVMAPKIDGALHLDALTRGLPLDLF
VLFGSAAGLLGAPGQGNYAAANVFLAALAHRRR-ADGLAGLCVDWGAFAEVGLAAASADGERLAARGLRSLSPAEGLAALGRLLDAGVTQAAVVRQWAEF
------------------FPAAATSA---MLSRLLTGPASA----R---------S------GD---G--EALRARLMGA----GAQARVVLLLERLREE
AARVLRLPELAVETPLTALGMDSLMGLELRNRIEAALGLRIPATLLWIYPTVTALAEHLAGL----------
>tr|A0A0Q9PS62|A0A0Q9PS62_9GAMM Uncharacterized protein OS=Frateuria sp. Soil773 GN=ASG87_18855 PE=4 SV=1
--------------------VVQPRV--YRWRELPFVRSISE-LGATVVAGAGGGV-AQLVALASRGVS--------------VSHWASITDAAIESLIL
VCDPITASGP----------------------MDDALVG---TFTELQALLGGNIARRVVILLPH----SRAAEADALLAARLGLSRALLHEYPEICWQV
LDLPDGLDERT---VEGVVVA---------------------------SQQL--GEWQAEPNRTYLISGAFGGIGLRLCHWLLDHGARHLLLCGRSGRSL
P--EQLR--AHAH----ALGAELRIEVADIGETHVREQLLTA-LA-GMPSLSGIFHAAGITDDGLLSTLNEKRVRAMLAAKCQGTRTLLDIAKSNGAALF
VSFSSMSAHLGVPGQSTYGAANAAMEAMTVAQG-GRHLCALSVAFGPWAEAGMAARLGSHDRAHAMGIRPLLPDQALASLGTLIQGGQSGVRLMFDWERF
------------------ANAVP----PCLLSQLPINDVPS----P--------RPH----NSP---DSLRALRHALASRE---TLADANEACLRYCVDV
FAAV-TAQTIDVELAPVALGMDSLLAIEIRRRLDRELGIHLEAATLLEIPSLRELAIYLLRQ----------
>tr|A0A0Q2MA37|A0A0Q2MA37_MYCGO Polyketide synthase OS=Mycobacterium gordonae GN=AO501_21650 PE=4 SV=1
--------------------DATRLLYTLGWNEVPPPTAETA-DDTWLIAGFDE-----------------------LADVVPGSLRTNDIVDPERWVQL
FAQAKDGGAPISGIVWRSGRRP-------TEFAGRLEGELDQLLTLVRTALQQDLKGGLWVVTERAVATEG-EPVDPVQAALWGLGRTVIAEQPQLRCRL
VDHDGSQDAVQW--LARLLAAPAAPVTEPELALRQGKFLVSRLLPWAR--------LAPRGDRTYLITGGLGALGLHTAAYLAQLGAGDIVLTSRHLPDA
---EAQQAIAIIE----RYRCRIHVFGADVGDESQVAELLNRIRA-ELPPLAGVAHLAGLLDDALLPQQSLERFRTTLAPKAFAAWHLHRLTKNDDLEFF
IMYSSISGVLGSPGQANYAAANALLDGLVAERN-AQGLTATSVNWGPWAKGGMAASHAARVNLGAQGLIPLDPTAALSALGELFAEGTGQATVIANWQRT
------------------AKVL--GGSRPAILDYVLPSAVA----A--------TQ------G------DSELLRQLHEI----PEGQRADFLTEYLQQE
VQSFLRLAPPAATSRFLDLGTDSLMAVELRNRLLGQFGGTISATAVFDYPTIRSLAEYLASQ----------
>tr|Q9KIV3|Q9KIV3_STRAT 8,8a-deoxyoleandolide synthase 2 OS=Streptomyces antibioticus GN=oleAII PE=4 SV=1
--------------------SAEHAMFRVEWVEEGSAGGA--GAGTWAVLGPRVPAAVRTMG----------------------TALDTPPQSLADLAA-
-L-----GDT--DVVVVTSLLSLAS--GA---------------------------SRLVLVTRHAMTVASDPEPDLLLAPVWGLVRSAQAENPGRFV-L
ADIDGDEASWDA--LPRAVA-----SAASEVAIRAGAVYVPRLARATD-------PAALDAEGTVLITG-AGTLGALVARHLVEHDVRRLLLVSRSGVAP
------DLAAELG----ALGAEVTVAACDVANRKALKALLEDIP--PEHPVTGIVHTAGVLDDGVVSGLTPERVDTVLKPKVDAALTLESVIGELDPALF
VIFSSAASMLGGPGQGSYAAANQFLDTLARHRA-RRGLTSVSLGWGLWHEASGLTGGADRDRMSRAGIAPMPTDEALHLFDRATELGDPVLLPMLNEAAL
------------------EDRAADGTLPPLLSGLVRVRHRP----S--------ARAG--TATAAPATGPEAFARELAA------APDPRRALRDLVRGH
VALVLGHSAIDAEQAFRDIGFDSLTAVELRNRLNAETGLRLPGTLVFDYPNPSALADHLLEL----------
>tr|I0J6Y3|I0J6Y3_SORCE Polyketide synthase OS=Sorangium cellulosum GN=pelD PE=4 SV=1
--------------------ALVGSVHEVTWRQVDPLPSFPP-QGAWLVFSDQRGVGAALKALSGVGQRCVRVFVGGGFERIEPDLYRIDPTKPGDYQRL
LREALGEEGSCRGAVHLFSLDA-------ETLSADLGRGSVSAAYLAQALVRHGFRPRLFLVTRGAQAVEG-EPVSVGQAPLLGLGKTIALEHPELRCTR
IDLSAAGGEGE---AELLARELGARGREDQIALRGEGRYVARLVRGSFLRRE--AAIALRADRSYLITGGLGGLGLSLARWLVEQGARHLALVGRRGPGP
---EAQQAIREME----EAGAQVLVASADVSRRGEVERLFARVEE-RLPPLCGIVHAAAVLDDHTLLEQSEESFRKVFGPKALGAWHLHALSEGRALDFF
VMYSSAASLFGSPGQGNYAAANALLDALAHERE-RGGLRSMSIQWGAFAEVGLAAAQDNGKRLSSRGGASFTPAEGLEALRRLLLNPRAEVGVVRQWLEF
------------------YPGT---AGLPFLAEVMAEDASD----R--------GS------G----GPPLAL-ERLKSA----PAGERPALLERHLLEQ
AGSVLRL-KMDRGAPFQSLGMDSLMSLELRNRLEASLGIRLSATILFTYPTAGALAEHLLER----------
>tr|H2JD28|H2JD28_9CLOT Non-ribosomal peptide synthase/amino acid adenylation enzyme OS=Clostridium sp. BNL1100 GN=Clo1100_0890 PE=4 SV=1
--------------------NIAEWFYVPQWVRSTPGYNCKSNSSQWLIFRDTLGISDEIKYFTKNGINVVTVTMGKSYERVDKKRFIIDPTQSGDYERL
FNEITSTGITIGKIAHFWGVDSIAEECQMGSFDCAQDAGLYSILKIAKALAKLEIHKEIRL-DVITNNVTGEEPTCPEKATALAASIVIPQEYSYIKSRC
IDIVVPEGHKGSNLVHQLGAELLSESPDRVIAYRSGFRWVMIYEQVKLEQQ-VNTEIPLKSQGVYLITGGLGGVGYALAEHIVKEYKAKVILTGRTVLEK
LETPQEDKISNIRKLALEYGTILLFDASDASDEDKMKYIVDRAEEEFG-AITGVIHSAGVLDGSLINDLDLAECKTQFNSKVYGLLVLERIFRDKETDFC
VLMSSIASVLGGLGHVAYSAANLFMDYYVQKINSFNNKNWKSVCWSEWQKDGSNEKITIGATIAE---LSMSPDEAIDAFERILSFE-------------
GQGQIVCSPGDLQQRLN--QWVKPNHTDSGESEKSENIPKTYRPVLSNR----------------------Y--------------VEPQSQIEKELAEI
WKDLFRISEVGIFDDFFELGGDSLKAITVINNIYKKFEVELPLTDFFKFSTIEKLGAYLTAS----------
>tr|Q4S1K1|Q4S1K1_TETNG Chromosome 6 SCAF14768, whole genome shotgun sequence OS=Tetraodon nigroviridis GN=GSTENG00025512001 PE=4 SV=1
----------------------QACFYHNELFVIPSEGNFQKGHIKAIVFEDKLGVAEGLRPYLHAESA---------LVENK-EYWT--ADE---LHRA
VLCSCTS-ADIENVLFLWGVEDLSRLSSEK-MLDSMVTCCQLFCRIVLALKDSKRSFTVR---VVTHRSSETTVRVSAGFVLSGLTRACAAEMVDLSFQL
IDLASVTCE---D-IKMLAHVIHTS-NLQEVTINKGELLTTRIERTDVTAGQSKSGPLFKQGCVYIVTGGLSGLGLETVKFIARNGGGCIATLSRSSLS-
--NEMQFEMESLRRRY---GVRILNVQCDVSVSMQVADAISNTKAFPFCPIKGVFHSAAVLHDAFIENLDASLFRKVLKPKVNGTLNLHRATLYKELDFF
VCYSSISSFIGNPSQANYAAANSFLDIFCHYRR-NLGLAGQSINWGPLNV-GLLFNKEFQRFLEAKGMMVMDVSDIHEALEKSLTLNRPQVICKFNFKNL
NIHVLSQ-------------------NASLRDRLAALVGSGLKDAD--TE----------------TC------------DTDTEL-ASSSHPRENVRSI
VSDISSISKLNEDVSLHALGIDSMLAMTLQNKIFQETGVNVPLVKILDPNTLANLESLVI------------
>tr|A0A060WJC3|A0A060WJC3_ONCMY Uncharacterized protein OS=Oncorhynchus mykiss GN=GSONMT00048563001 PE=4 SV=1
----------------------ESFFFHNELFTITDNTHVS-RKPKALIFEDILGVGTALRPYLHQTSF---------FVLNR-EFGT--NPQ---VRDL
VSHSLGDAVDSQEVLFMWGVQDLSHLSTEM-ALECLVDCCEHYRQIVLALKENECSCTIR---VITYRSAETTVHVSPGFVLSGMTRACAAEIPGLSFQL
IDLASVSSE---D-IQALVHVINTS-KHPEVMISRGQIYSTVIVRTPIK---SSEGTLFKKSCVYIVTGGLSGLGLETVKFIAHRGGGCIATLSRSPMS-
--AEMQLEMDTLQRRC---GVSIMSVQCDVSVSGQVVNAITAIQMFPSCPIKGVFHSAAVLHDALIEALDRSHFNEVLRPKVNGALNLHYATQHNKLDYF
VCYSSISSFIGNASQSNYAAANSFLDTFSHYRR-NLGLAGQSINWGPLNL-GLLLNRDFQRFLEAKGMMIMEVSEVHEALEKCLLMNNPQVICKFNFRNL
SNHVLSQ-------------------NASLRGRLTALVEQELENTN--MT----------------EP------------IVQQ-----LSTAHENVRAM
LSEITSVSIVNDDTALYALGIDSMLAMTLQNYIFQERGVNVPLVKLLDPNTLSTLVTLLK------------
>tr|H2LF10|H2LF10_ORYLA Uncharacterized protein OS=Oryzias latipes PE=4 SV=1
----------------------EEYFYHNSFTIVPEGS-TASPPPKALVFSDELGISEGLKQHLDQESR---------YVSITHANHIV-NDG---FLSL
LANLSTDIKNFDEALFLWYTEDLTSLPPDCHLLQNLPNCCDVFRQIVVELRKFKFPHAIR---VVTYRSSDITVRISPGFVFAGLTRSFAAEMSDLSFQL
IDMGMISPE---N-ITALSEVLRKYPKFPELVVKDGKILRPSIVHSPLDFT-PTKKQFFKERAVYIVTGGVSGLGFETVKFISQRGGGNIVSLSRSKPS-
--AEVQQKMYALEKEH---GNCIASMQCDVSVFENLHMVITAIQKFPGCPIRGVFHSAVVLHDGIVEALNRSLYEKVFKPKVNGVLNLHHATQHCPLDYF
VCYSSISAFLGNPSQSNYAAANSFLDMFCHYRR-QLGLPGQSISWGALKL-GLLHNKELQHILEVFGIMGLELAEIRKSLEQCLILNRPQAVCRFNFKNI
SYNVFSH-------------------NSSLTMRLYALVEEAVRKSR--QG----------------FF------------QT-K-QTN-LIPPREYITTL
LSETLGLDKVRDESFLSALGMDSMQAMTVQNLILQERSVSLPLVKLLDPTTLSTLVASLT------------
>tr|A0A0P7ZBH4|A0A0P7ZBH4_9TELE Putative polyketide synthase 16 (Fragment) OS=Scleropages formosus GN=Z043_102245 PE=4 SV=1
----------------------REFFFESEINVTATENN-SSHKPKALVFADLQGVALALKQYLHDDSS---------YMDFKHDK-----EE---VLGL
LLAL-DFSLDHEEILFIWGVFDLTNLETEN-VMQRLLTCCECFRQLVLKLYEAKFSHPLR---IITYGSSEKTVNINSGFVLPGLTRGCAAEFEFFKFQL
IDIESISYK---D-IEALGQVIRSYPKYPEIIISDGQIHSVTLSHTPFKDNHEKQKVRFQRNAVYVVSGGLSGLGFETVKFIAERGGGYIVTLSRRKPT-
--HETQLVIDSLQSTY---RITILCQQCDISITSQVEEAFSDIKKFPH-PVKGVFHSAVVLSDGLISTLNESLFEKVLKPKVNGVLNLHRVTRKSKLDYF
VCYSSIASCMGSAAQSNYCAANSFLDLFCHYRR-RMGLAAQSINWGPLNL-GLLLNKDLHTFMESKGVTPMSISEAHESLEQSLLLNSPQIVCKFSFKNL
AA--SRQ-------------------NDSLRQRLYGVLETVLQTAM--EP----------------DP------------RVEMVNSSLTSAPEEYIRLL
LCEICDAELLEDNVLLTTLGVDSMLVITLQNHIYWERGISIPLVKLLDPQTLSTLISYLK------------
>tr|F6ULR9|F6ULR9_MONDO Uncharacterized protein OS=Monodelphis domestica PE=4 SV=1
----------------------DDFLFENKWKPISPVPVHSMDSPPFLVFADKFGIAQQLKKYLHSQSK---------YITSEEWEAMQ-NSE------E
SGKDRKKEEGFHDVLFMWGIQKFSEETPGMLITKYSAKCCETFSQVILALRGKNAPCSVT---IITHRATSRNIQISPGPVLSGMTRCCFVEVPDITFKM
VDISFPSTQ---D-IASLAEAVIKYKDYPELWIDQGRMYISEIRRTPYELPLAAEKKLFKSNAVYIVSGGLSGLGFETVRFIAQKGGGSVVILSRRSPN-
--AEQQLEIQSMEKQNE--GCKIISLQCDVTVHSEVNKVISSINIFPKVPIKGVFHSAVVLDDAHLEALNVSRFEKVLSPKVAGVINLHYATRGHKLDYF
VCYSSVTSFLGNATQANYAAANSFLDMFCHYRR-NCGLAGQSINWGALNL-GLLLNKDLQKFLASKGILTLQKSEIYEYLEKSLLLNNPQAVVKFDFKAL
KNYFFSQ-------------------VPSFKIRFAKFLQNEYNAVA--EP----------------N-------------SMAH-QDSSAMATQDYIYSL
VSELSNINPITMNTPLMSLGMDSMSAMTLQNRLFQDKKVDVPLIKLLDPNTLMTIQSLLE------------
>tr|M4A1P6|M4A1P6_XIPMA Uncharacterized protein OS=Xiphophorus maculatus PE=4 SV=1
----------------------EEYFYHNDFSIIPESS-TSSKPPKALVFSDHLGISKALQPHLDQESR---------FVSFTHAKDIL-SNG---FPSL
LSNLSANIKNFNEVLFLWGKEDLTSQSPDA-VLHNLASCCEIFRQIVQELKRIQFPKAIR---AVTYRSSDITVHISPGFALAGMVRSFAAEIPDLSFQL
IDIGSIFTE---D-IKALSEVLRSHPKYPELVIKDGLILKPSIVRTPLEVT-PVKKQLFRKRAVYLVTGGLSGLGFETVKFISQRGGEYIVILSRSKPT-
--AEVQQEILNIQQQY---GNSITSMVCDISVSERVQKVILEIQKFKGFPIKGVFHSAVVLHDGLIETLNRALYEKVFKPKVNGVLNLHHATKHCHLDYF
VCFSSISAFLGNASQTNYAAANSFLDLFCHFRR-KLGLPGQSISWGPLNL-GLLLNKEFHRFLEAKGMMLLDVVEVHKSLEQCLILNRPQAVCRFHFRII
RYNILSQ-------------------NKALSLRLSVLVNEAFQNFK--EE----------------ES------------KT-E-QSD-SVSPKEYVFSL
LSETIGIDQLSDDSPLTSLGMDSMQAMTLQNMMFQERGVNVPLVKLLDPNTIWTVVTILS------------
>tr|H2MBT4|H2MBT4_ORYLA Uncharacterized protein OS=Oryzias latipes GN=LOC101169644 PE=4 SV=1
----------------------KEYFYHNTYTVASEKV-ASCSPPKALVFSDHLGISEGLQKQLDQESR---------YVPVTHAKDIL-TNG---FSSL
LANLKTCIKNFDEVLFLWGKEDLTSLKADT-VLHNLASCCEVFRQIVLKLKQIQFLKSIR---AITYRSSDITVHVSPGFAIAGMTRSFAAEIPDFSVQL
IDVCSVSSE---D-IAALFEVLRSYPKYPELVVKDGQIFKPSIVRTQPEVT-PAKRQMFRRRAVYIVAGGLSGLGFETVKFISQRGGKHIAILSRSKPT-
--PDVQQEINNVEKQC---GNRIKSLECDISIFEHVHDALTTIQMFPGCPVRGVFHSAVVLHDGLIESLDRSLYEKVLKPKVSGVLNLHHATQQCQLEYF
VCYSSISAFLGNASQTNYAAANSFLDMFCQYRR-RIGLPGQSINWGALNL-GLLLNKEFQRFLEAKGMMVLDVAEIHKSLEQCLLLNQVQAVCRFHFSNI
RYNILSQ-------------------NKALTMRLSALVEEAFQKSR--EV----------------DP------------QL-R-ETK-AVSPKEYMFSL
LCETVGVDLLREDSLLSSLGIDSMQAMTLQNLIFQERGVNVPLVNLLDPSTFSTVIALLS------------
>tr|G3NMY1|G3NMY1_GASAC Uncharacterized protein (Fragment) OS=Gasterosteus aculeatus PE=4 SV=1
----------------------EEYFYHNTFSVIPEGL-TSAPPPKALVFCDRIGISSALQPFLDSRSS---------FVSFTNEKDIL-SHG---LPSL
LANLNTALKNFDEVLFLWGKEDLTSLPAED-VLQICASCCETFRQIVLELKRICFPNSVR---AVTYCSSDITVHISPGFALAGMTRSFAAEIPDLSFQL
IDIRTISAK---D-IAALVQVLRSHPKYPELVVKDGLILKPSIVRTPLEIA-PTKKQLFRRRAVYIVAGGLSGLGFETVKFISQRGGGYVVVLSRSKPT-
--PAVHLEMHNVETQC---GNCITAMECDVSVSESVHDVVDAIRKFPGCPIRGVFHSAVVLHDGLIETLDRSLYQKVLKPKVNGALNLHHATLRCQLDYF
VCYSSISAFLGNASQTNYAAANTFLDMFCQYRR-KLGLPGQSINWGALNL-GLLLNKEFQRFLEAKGMMVLDVAEIHKSLEQCLVLNRPQAVCRFHFRNI
RYNILSQ-------------------NAALTMRLSALVDEAFQKSK--EQ----------------DS------------RT-K-ESE-SVSPRDYVVSL
LCETIGVDRLKDESPLSSLGIDSMQAMTLQNRIFQERGVNVPLVKLLDPNTLSTVVLTLS------------
>tr|A0A087XTQ5|A0A087XTQ5_POEFO Uncharacterized protein OS=Poecilia formosa PE=4 SV=1
----------------------KSLFFHSETVALAEERDVDGSKIKAIIFEDHMGIAKGLRPYICTDSV---------IVGIR-KKLS--ADE---VKCL
VIHSLSN-DNLKKVLFIWGVENLTHLSSEM-ILESFVTCCETFRHIVLSVKETKRLCAIN---VITYRSTELTVHVSPGFVLSGMMRSCSAEIADIHFQH
IDLASVTSE---D-IQTLACVIKTK-QQQDVRISKGQASTTRIAQTPVKDSRTKPARLFEQRCVYIVTGGLSGLGLETVKFIAHNGGGCIAVLSRSVPS-
--DEIRFQLDLLQKRS---GVSVLNIQCDVSESKQVVDSITKIGRFPSCPIKGVFHSAAVLHDSLIESLDESLFRKVLKPKVSGTLNLHFATLHNKLDYF
VCYSSISSFIGNASQCNYAAANAFLDTFCHYRR-NLGLAGQSINWGPLNL-GLLLNKGFQKFLETKGMMTMGVHEVHKTLQRCLVMNRPQVICKFNFKNL
SLHVLSQ-------------------NPSLRERMATLVETAIKDEI--HK----------------TP------------KVQH-----SFTAYETVRII
VSEMLNIDAVDDDSCLSALGIDSMLAMTLQNKIYQETEINVPLVTILDPNTLTTLVSFVQ------------
>tr|H2MBT8|H2MBT8_ORYLA Uncharacterized protein OS=Oryzias latipes GN=LOC101169887 PE=4 SV=1
----------------------QSLLFHNESVPVGLQTDLENCKIKAIVFEDKLSIAKGLKPYLSPESV---------LVEGKG---KLTADK---VRDM
VLDSLSN-EALTDVLFLWGVEDLTHLSAEM-MLNSLVTCCEFFRQIVLAVKESKRSCTLR---VITHRSTEMTVHVSPGFVLSGLTRACAAEVVDLSLQL
IDLAFVTSE---D-IQVLARVIRTC-KHQEVRISNGQIWGTSITQTQVKIEHKRPEKLFKKKGVYIVTGGISGLGLETVKFIACNGGGCIATLSRRILS-
--EEMQFEMNLLQKRF---GVSIIHIQCDVSSLVQVVNAISEIQRFPSCPITGVFHSAAVLHDALIPSLNEDLFRKVLQPKVCGVLNLHHATLHNKLDFF
VCYSSISSFIGNASQCNYAAANSFLDAFCHYRR-NCGLAGQSINWGPLNV-GLLLNKEFQRFLEAKGMRIMSLHEIHETLRMSLVMNRPQVICKFNYRNL
HHHVLSQ-------------------NASLRERLSVLVAARLKDG----S----------------EP------------KVQP-----LSSTRQRLRTV
ISEMLNTRELEDDASLCALGVDSMLAMTLQNKIFQETGVNVPLVLILDPSTLTSLEEFVH------------
>tr|E6ZJA9|E6ZJA9_DICLA MxaC OS=Dicentrarchus labrax GN=MXAC PE=4 SV=1
----------------------QSRFFHNEIIAIPDKRDLQKGQIKAIVFEDKLGIAKGLRPYIHPESA---------FVESR-QDWM--ADQ---VRNV
VFHSLTS-VDLENVLFFWGVEDLSYLSSEK-ILDRLVTCCELFRQIVLALKENKRCYTVY---VITYRSTETTVHVSPGFVLSGMTRACAAEMMGLSFHL
IDLASVTNE---D-IQMLVHVINSC-NQQEVMISKGHASTPRIVRTPMSYRPTRPGQLFKQRCVYIVTGGLSGLGLETVKFIARNGGGCIATLSRSTLT-
--EEMQFEMELLQRKY---GVLVMNVQCDVSVSMQVVDAVSQIQRFSSCPIKGVFHSAAVLHDALIETLDQSLFEKVLQPKVSGALNLHYATLHSKLDFF
VCYSSISSFIGNPSQCNYAAANSFLDTFCHYRR-NLGLAGQSINWGPLNL-GLLLNKDFQKFLEAKGMMIMDVCDIQEALEKCLLMNRAQVICKFNFKNL
NIHVLSQ-------------------NASLRERLSALVEIELKDDI--SN----------------EP------------TV-H-----LSSTHGSVRTF
VSDISNVSVLDDDSALCALGIDSMLAMTLQNKIFQETGVNVPLVRILDPNTLATLETIVM------------
>tr|A0A0Q3S445|A0A0Q3S445_AMAAE Putative polyketide synthase 1-like protein OS=Amazona aestiva GN=AAES_187730 PE=4 SV=1
----------------------NELMFENKWKEISLSQINRGAMPRVLVFADKFGIAEKLKKYLHPDSR---------YIMYEDWEXLL-EGH-------
-TQNKRAEENYDEILFLWGIQKLNERFPSKVVDX-LSKCCEAYRQVIVALREKMSRCSVR---VITYRTTERYVHVNCGFALYGMTRACIVEAPEIXFQM
IDLSSASSL---D-ISVLADVLVKHKEYPELCIXQGRTYIAEIRRTPFVDAGESQ-KLFKPNAVYVVVGGLTGLGFETVKFIAKNGGGCIAIFSRKMPS-
--NEKQEEMKALQEQYK--EIKVLFVQCDVTSTNDVEKAFQSVSIFAGNPIKGVFQSAVVLHDGRLEVLKLADFQKVLSPKVAGTLNLHWATRGQQLDYF
VCYSSVTSFLGNSTQTNYAAANSFLDIFCLYRR-NCGLSGQSINWGALNL-GILLNQNLXSILESKGIDILQVHEIHEYLRKSLLMNNPQVVAKLNYQTL
LHHVFSQ-------------------ITSLRSRFLSFLSEEYRNKL--ET----------------SE------------KIQV-EDAALIKPEDYIISL
VTELTNLSPLTMNTALSSLGIDSMLAMAIQTRVFQERKVNIPLLKLLDPHTLSNLVVVLE------------
>tr|W5L5F9|W5L5F9_ASTMX Uncharacterized protein OS=Astyanax mexicanus PE=4 SV=1
----------------------KEFFYHTDFKVNSENQNPKTPFPKALVFADHLGLAEALKKHLAPTSK---------YLSFKHAEELL-HEG---FQAL
MLKLNSDVKPFDEILFIWSDTNLTTCSADR-TLETMVNCCEVFRKIVTALKSGSFPHSIR---TVTYRASETTVQVTLGFVLSGMIRACAAEVSELLFQL
VDISSVSSQ---D-VAAFAQVLKSYPKYPELLVKDGQVLKSNIVRTSLRNSQLGAKQLFQKRSVYIVTGGLSGLGFETVKFIAQRGGGHIVILSRSAAS-
--PEMQQEISTVKNQN---DVEILSLQCDVSVIRQVEKVISVIQTFPMCPIKGVFHSAVVLHDGLIESLNRALYEKVLKPKVCGALNLHHATRHCKLDYF
VCYSSISSFIGNASQSNYAAANSFLDTFCHYRR-NIGLAGQSINWGALNL-GLLLNKDFQRFLESKGMAIMEVNEIHQCLQECLLLNRPQVICKFNFRNL
RTHVLSQ-------------------NASLRMRFSALVQEAFRNDQ--IA----------------EL------------ET----TKSKSSPHEYVRSV
LCNTLGVKELSEDMTLADLGVDSMLAMTLQNLFAQEKGVNIPLVKFLDSSTLAALAAVVA------------
>tr|W5ML50|W5ML50_LEPOC Uncharacterized protein OS=Lepisosteus oculatus PE=4 SV=1
----------------------EEYFFHNELTAISEDFNSS-HRSVALVFADQLGVAQALRQHLHHSCT---------YIPFQ-DSGKFADRE---LPAL
I--SQHVPRQYKEVLFLWGIQNLNNLTTEE-VLECLVCCCEVYRQIVKTMKEKKSPNVIR---AVTYRSTENTVHISPGFVLSGMIRSCAAEIPGLTFQL
IDIGSVSSE---D-ITALAQIINSHTRYPEVVISKGQIFTTEITRTAIKNVQETEKQLFQQNSVYIVTGGLSGLGFETVKFIAERGGGCIAILSRSAPS-
--AEKKIEITDLQNHF---GVSVISLQCDVSVSEDVMKAITDIQRFPSCPIRGVFHSAVVLRDGLIDILEKSHFEKVLRPKVNGVLNLHYATRYCKLDYF
VCYSSITSFIGNSAQTNYAAANSFLDVFCHYRR-NLGLSGQSINWGALNL-GLLLNREFQRFLEAKGMMIMEVPEIHECLEHCLLQNNAQVVCKFSFKNL
SNHVLSQ-------------------NASLRMRLLALVTEELKNTR--ET----------------EP------------QVEE-S-TLASSADEYVKSL
LCEVGNVDVMRSDTGLSALGIDSMLAMTLQNRIFQDRNVNVPLIKLLDPSTVSSLVLVLQ------------
>tr|W5K168|W5K168_ASTMX Uncharacterized protein OS=Astyanax mexicanus PE=4 SV=1
----------------------EEYFYHNSYSIATEYDGISSLLPTSLVFADHVGIARGLQPYLDESSK---------CISPTKTKALL-EQQ---FDSL
LSELKPNFTHFAEILFMWGSGDLTSYKTEN-VLDCMSTCCEILRKIVAGLKAMSFQNSIR---VVTYRSSEDTVYISPGFVLSGMTRACAAELPDLSFQL
IDMSSVSVD---D-IKALAKVLKSYPKYPELVIKDGQILKPQISHTTGINTQPKAKKLFHKNSVYIVTGGLSGLGFETVKFIAQRGGGTIVILSRSAPS-
--HLMEQEINHVKNQC---QSLITCLQCDVSVSEHVHQVVAQIKQFPSNPIKGVFHSAVVLHDGLIESLNKSLYEKVMSPKVNGVINLHHATKRCNLDYF
VCYSSISAFLGNASQTNYAGANTFMDTFCQYRR-NIGLPGQSINWGALNL-GLLLNKEFQRFLEAKGMMILEVTEIHESLEQCLLINKPQAVCRFNFKNI
RYNVLSQ-------------------NKALTMRLSALVEEAFKKAK--VV----------------DS------------SSKQ-TTNPVSSPKEYIKSV
ISETIGVEKLTEETPLSTLGLDSMLAMTLQNLIFQEKGVNIPLVTLLDPDTLSGLVKMFG------------
>tr|Q5RJ12|Q5RJ12_DANRE Novel protein containing a beta-ketoacyl synthase, N-terminal domain (Fragment) OS=Danio rerio GN=si:dkey-61p9.11 PE=4 SV=1
----------------------KEYFFHNSFDIISEDD-MLDTQIKALVFSDQLGIFKALQQHLDSRSR---------CVSFSDSSTLL-EGG---VETL
LSKLASSVKNFQEILFMWSDADLTTLESEK-VLESMAGCCEMFRKTVRYLKALQFPGVIR---VITYRSSESIVSINPGYVLTGMTRACAAELQELSFQL
IDMGSGTSE---D-IKALVQVLRSYPKYPELVVKEGNILQPEITHTPLPSMQPK-NNLFKKKSVYIVTGGLTGLGFETVKFIAQKGGEHIVILSRRNPN-
--PEMQQEISQLSSRC---GSVIKSLPCDVSVSEQVDQTIANVKLFPSSPIKGVFHSAVVLHDGLIERLDKSLYEKVMRPKVNGVINLHRATIQCNLDYF
VCYSSISAFIGNASQTNYAAANTFMDTFCQYRR-NIGLAGQSINWGALNL-GLLLDKVFQRFLEAKGILLLEVPEIHESLEQCLLINKPQVVCRFSFKNS
WNSVLSQ-------------------NKSLNARLFKIAKEAFIRAG--VN----------------PS------------RPEQ--PMTSSSPHDYLRFL
ISETAGVEKLNDDVHLFELGIDSMLAMTLQNHIFSYRGVNIPLVTLLDPNTLSTITKILE------------
>tr|W5K186|W5K186_ASTMX Uncharacterized protein OS=Astyanax mexicanus PE=4 SV=1
----------------------DSYFFHNERLAVQASSNIC-SKPKAVVFEDTLGIASALKPYLHPSSV---------FFSPADANWSTSPAE---L---
-----QVANGAEKVLFVCSFQNLSHLKPQS-VLEHLVDICELYRQVVLVMRKCKHLLTIH---VVTYRSSENTVHISPGFVLSGLTRACAAELSEISFQL
IDLGTVSTE---D-IEALVYVICSYKEYPEVMIRKGQVYSTVITRTPINTTKPKTKHLFTQKAVYIVSGGLSGLGFETVKFIAHSGGCCIATLSRNAAN-
--EETKLQISRLTKRY---GVKILTLQCDVSVSEQVLEAITIIHKFPSCPIKGVFHSAAVLHDGLLETLDKSIFEKVLRPKVNGALNLHYATVNSKVDYF
VCYSSISSFIGNASQANYAAANSFLDTLCHYRR-NIGLAGQSINWGPLKL-GLLLNKGFQTFLESKGLMIMEVPEIHEALKHCLLENRPQVVCKFNFRNL
RNNVLSQ-------------------NASLKGRLTALVEKELESKL--VN----------------EP------------RKN-----LQSSFDEYIRCM
LSNICNVDALEDETVLATVGIDSMMAMTMQNRMFQETGVNIPLVALLDPNTVSSLISLFT------------
>tr|A0A060WJB8|A0A060WJB8_ONCMY Uncharacterized protein OS=Oncorhynchus mykiss GN=GSONMT00048557001 PE=4 SV=1
----------------------EEYFFHNDFSVVSDDY-KPINKPKALVFADQIGVSEAMQKHLSSQSQ---------YISFTHANDLL-SRG---FKAL
LSKFKSDL-SFAEILFVWSNDNVTSHETEA-ILENMVNCCEMFRQIVLELKAMKFPNSIR---AITYRSAENTVRISAGFALSGMTRSCAAEMSDLSFQL
IDISSVSTE---D-IRALSQVLDSFPQYPELVVKDGQILKPYIVHTPTESS-PKPNQLFQKNSVYIVTGGLTGLGFETVKFIAQRGGGYIVILSRSSPS-
--TDLQQEISNIESQS---GATVVSLQCDVSISAQVVNTVIAIERFPSCPIRGVFHSAVVLHDGLIEILDKSLYEKVLKPKVNGALNLHHATKLCKLDYF
VCYSSISAFIGNAAQTNYCAANSFLDTFCQYRR-NIGLAGQSISWGALNL-GLLLDKDFQRFLAAKGMMVMGVAEIHESLEQCLLLNRPQVVCKFSFKNL
MRHVLAH-------------------NASLNIRLGALVDEGITKEK--GE----------------VA------------GYDQ-TTV-SMSPSDYVKSV
LRETLGVENLNDDSSLTALGIDSMLAMTLQNLLFQDRGVNVPLVKLLDPNTLSTLVAMLK------------
>tr|A0A060WRM8|A0A060WRM8_ONCMY Uncharacterized protein OS=Oncorhynchus mykiss GN=GSONMT00048561001 PE=4 SV=1
----------------------EEYFFHNDFRVVSEDI-KSSQARKALVFSDQVGVSKAMQPHLSSMSK---------YIPFAHAKEFL-NHG---FPTL
LANLNSDIKNFEEVLFMWGEEELTSVKTET-VLENIVNCCEIFRQLVLELRASNFPNSIR---VITYRSAENTVRISPGFALSGMTRACAAEMADLSFQL
IDISSVSTE---D-IRALSQVLKSYPKYQELVVKDGLIFKSDIVHTPMESIQPKPNQLFQKNSMYIVTGGLTGLGFETVKFISQKGGEYIVILSRSSPT-
--PDIQQEICNLEKQY---GAHIICMGCDVSVSEHVLRAIGLIKKFPSCPIRGVFHSAVVLHDGLIESLDKSLYEKVLKPKVNGALNLHHATKHCKLDYF
VCYSSVAAFIGNVSQTNYAAANSFLDIFCHYRR-NIGLAGQSINWGPLNL-GLLLNKDFQRFLEAKGLMVMDVTEIRESLEQCLQLNKPQAICKFNFKNM
KYNVMSQ-------------------NASLTMRMTALVEEAMQKDK--LK----------------ES------------RSGH-NAA-SSSPSGYIRSV
LSETIGVDKLNDDSPLSALGIDSMLAMTLQNLIFQERGVNVPLVQLLDPNTLSTLISNLM------------
>tr|C3ZIP9|C3ZIP9_BRAFL Putative uncharacterized protein (Fragment) OS=Branchiostoma floridae GN=BRAFLDRAFT_247081 PE=4 SV=1
----------------------EDLVFTTTWTPAQSQWGNEFCELKCLVLQDDCGISNQLEPFVSSDSV---------FISLEDFKRTDYRNDERAFPKL
LQEM-DVN-NFDFVLHCCGISQLDPEKLDAEALTRVELACASLRQVMKMLITDGSRVPVK---IITRNVQFSDVSDLAGAPLWGLIRCAIREGAYPLLQL
VDLSSGNNF---E-IYTLLHELVARESYTEIMCVQSAKYYLEIVSSTLRSEQCGRKALFRRDASYVIVDGLTGLGFFTIEFLAERGAGNIVTVSRTQPQ-
--ADTVTELRRVGEKY---GSKIICLVADVTSYKSMTAALDKLDCLPGIPLKGVFLSTAVSSDRILINQSHAQFKMGLDAKVVGTWNLHLTTRHLNLDYF
VCYSSMSSVLGTGGQTSYGAANAFLDGIACLRR-QMHMVGQSINWGALQL-KTLHRDKMAKILEQNGIRDLYKDRVSECLENCLLLNPVQIVVDLDRSRL
AA--MTK-------------------RFPDVRRFEKLVGDIDDVTA--DD----------------VM------------LS--TAQGRREAIGALTRNV
FVNLLNAEPVTMQRSVVNMGMDSLLALTAQNIFKNKFQVDVPWIALLGKKTIESINDQVF------------
>tr|C3YVH3|C3YVH3_BRAFL Putative uncharacterized protein (Fragment) OS=Branchiostoma floridae GN=BRAFLDRAFT_205831 PE=4 SV=1
----------------------ADMFYTTSWTGYSSDWKNKTCHLRCLVLEDECGIMDHIKPLVSSESV---------FIPLQDIESIDYKNDEQALQKM
LQVN-NVNADVDLVLHCCGISLLEAETTDTESLARIQLACASLRQLIKMAVASGQTIPLK---VVTRNSSV----DLAGTPLWGLVRCAIREAAYPSLQL
VELSRGDHW---E-THTLLHELVTGESYTEIMFVRSKKYFLEIQSSTLHAEQCTRQTLFRKDASYIVVGGLTGLGFLTVRFLAERGAGHIAIMSRSQPK-
--QDVVAELKTLEETF---GARIIYLQADVSSYDSVNSALEELISFPRIPLKGVFHSAVVISDGVLINQDHVQFQRGMGAKVSGTWNLHLATRHLNLDYF
VGFSSVSSVLGNGGQTSYGAANSVLDGIVHLRR-QLGLSGQVINWGALQL-GLLERDRVAKFLEQIGILPIDKDCICESLETCLIANPSQTVVNLDRPKF
RQ--FLQ-------------------ELPDFKRLEVVLGGPAESSP--DD----------------TA------------VVKMDKRAQQKSLGDFTRLL
FVKLLSAEDVNMYTSIVNLGMDSQLALNAQSIFRKQLNVDVPVVALLSQETVQSISDLV-------------
>tr|A0A0Q6Y750|A0A0Q6Y750_9BURK Uncharacterized protein OS=Rhizobacter sp. Root1238 GN=ASC98_22085 PE=4 SV=1
----------------------VGDVYELQWVAATDGSLATEATGDWLLLSDDTGVAAALRASLQRHGGRCTEVVGERFQRLASNRWSVDPRDAAQMQSV
VTDWR-SH-TPRGVVALWSLDTPGADPRD---AAAELRASGSLLHVLQALAADAEPVALW---LVTRGAQAVGPESSAAAGAWAFLGVLAVEHPDIPLRA
IDIDATGIEALA--------ELLS-SPRPRVALRGPTRHEPRLARRHAPSTQGRVSFEVRPDASYLVTGGLGALGLHTARWLQRAGARQLALLGRHAPS-
--AEAQQAIHEIEAA----GTQVRCFAADAGDGAALQRVLETVREMA--PLRGIVHAAGTLDDGIALRQQWPRCAAVLHGKARAAQHLHELTRTLPLDFF
VMYSAAGLLLGAPGQCAYAAANAELDALAQMRR-AQGLPALSVAWGPWAQGGMATQLAGHDPWRDRGLLPIEPAHGFERLEQLLRDGAVHAVLTIDWQRF
IATL---P------------------AGVDAA----FFDGVLPRAS--TP----------------APAAA-------DASPATPSGRRAAALAAHLTER
ALQVLGLEPPDPKTPLKDLGLDSLMAVELRNALTRSIGRPLSATLLFDYPTVAALTAHLM------------
>tr|A0A062U1G3|A0A062U1G3_9RHOB Uncharacterized protein OS=Hyphomonas sp. T16B2 GN=HY2_01100 PE=4 SV=1
----------------------PVELYTTDWHPIELQS--AKVAASWLIISGDHQ---ELAKALAA-GKDNAR--IIS-------------AADPEALDK
ALDWL-STPEPRQVLDLSSLDTDDA-IAV----------IKTGLAHVQCV--ASRSIRYA---SISQGAFQTGQHSISGRALQGFVSTAALEHPELEIHC
LDIDPDTDEGHEQ-VSEAVCGAVS-AGPVKLALRDGKWFAPRLAPAKQLE-EPRRKPVIHADGSYLITGGLGGLGLYTAKWLASQGAKHIVLTGRSAPD-
--EKAKNMITEIEAT----GASVHVFQADIGDKDAVAALLATIDTLP--TMKGIVHAAGALRDGPVMTRTPEDVDIVVQGKLRGAMFLDQMTRDLSLDFF
VLYSAAGASLGAPGQSLYAAANSGLDALAAARR-RDGFAALSVAWGFWSNAGMGARLAGRDTWSTRGLGAITPENGFPAMATLLASGNPAMAAKVDWARF
LETA---P------------------KDIDLS----MFDGLSRDTG--LA----------------ASNTP-------SSSASLSREAIKVELRRITESA
VRSIIGMDEEGRAEPLKDLGLDSLMAVELRNDLARTLGLRLSATLLFDYPTIDRLCGYLA------------
>tr|I4MQ95|I4MQ95_9BURK Polyketide synthase OS=Hydrogenophaga sp. PBC GN=Q5W_1772 PE=4 SV=1
----------------------EELLYHVHWQALPAAG-REPVAGRWLLLADRGGVGDALAAQLQQQGAHGTVLAGDALDAVAQ----------------
-------G-PWRGVVHLWGLDTPSFADAATPDLSDDWPALGSALALAQ----ALVPAPLF---LVSRGACVVVGEQPRAAGLDGLVSVIEQEHPELRARA
IDLDPADSAVQAD---RLLAELLA-GVPSRLALRGARRFAPQLRRPTADAAQT--AATVRADASYWITGGLGGLGLETARWLVAGGARHLVLSGRRAPD-
--EHAQSVIAELRAQ----GATVRAVEADAADGARMQAVLEEIRDMP--PLRGVVHAAGALDDAVLQRQTWPRAQAVLRGKAQGAWVLHHITRDRPLDFF
VLYSAAGLWLGAAGQGLYPAANARLDALAQARR-RAGLPALSVAWGAWGGVGMAARGAGHDAWGARGLRPITPATGFAALARAMREDAAHLVLAIDWPRF
LAQR---P------------------GAADSE----LFRAVAGGAG--PT----------------ATAAS-------APTPGLPSGQRRAALVAYLGER
TLQVLGLDAADPRAALKDTGLDSLMAVELRNALAKAFAQPLPATLLFDYPTLDALAAHLL------------
>tr|A0A059G3R7|A0A059G3R7_9RHOB Beta-ketoacyl synthase OS=Hyphomonas oceanitis SCH89 GN=HOC_15547 PE=4 SV=1
----------------------PVKLYTTSWKAESRDGEPNDHAQSWLVISDEKLG-EELAEALAD-IAVCAR-MVRS-------------EAAPSEFNA
ALDWL-ADPEPRQIIDLVGLARDLDASEH----------VIRTLRHTQAI--AKSSTSLA---ILTQGAFATENLSISGASVQGFIATVSLEHPELSIRG
IDLDPAVNNYDKE-LALALSAQLS-RGSAKLAMRGTEWLSPRISPANLSD-EPRLTAPVRTDATYWITGGLGGLGLYTAQWLANSGAQHIVLTGRRSAT-
--ESAKAAIAEIEKS----GAIVHVLKNDVGDDTSNAQVLALINTMP--PLRGIIHAAGTLRDGPALTREPEDVESVFRGKFQGACSLDRQTRELPLDFF
VCYSAAGTILGASGQTLYTAANTALDALIVKRV-REGYPGSSIAWGGWSGAGMLAGLSAREGWAERGLVDITPDSGFPQLEQALQSGIPNIAVAVDWRMF
TATA---P------------------SGLDLG----PFSELTHSSA--IA----------------SLSA--------GRIPTATPSERRAKLQQCVETA
ARDIIGLDSPDPDHPLKDMGLDSLMSVEMRNELSRGIGLRLTATLLFDYPTVNRLIEYLD------------
>tr|E0UL81|E0UL81_CYAP2 Beta-ketoacyl synthase OS=Cyanothece sp. (strain PCC 7822) GN=Cyan7822_5857 PE=4 SV=1
----------------------GDWLYQNTWQPQPPVSD--ETANRWLIFSDQSHLGQQLIAQLQQQGHDCVIAAGSTYQLLAQNLYQVNPSNPEDFQRL
LAESLD-NAAYGGIIHLWNAENCSENPPDLALLAAQVKACASVLYLVQALAKANMASRLW---LVTRGSQAVD--NVEQASLWGLGGVIAMEHPALHCTR
LDLAPTPE-T-EE-VQNLLKEFAASS-ETQIAYRQNSRFVLRLERYRMDEQE-KRENLINSESSYLITGGLGALGLKVAEWLIEG-AKSVILVGRQHPS-
--DIAQAKIAQLEAS----GAKVVTMQADISNAQAVDHLITTIASMP--PLRGIIHAAGVLKDGLVTGQTWEQFIEVMKPKVMGSWILHQSTRDIPLDFF
VCFSSIASVLGSPGQSNYAAANSFMDMLAHYRR-SMGLPALSINWGPWSEGGMTTGLSDQERWAAQGLNLISPEQGLKFLEKLLKQDAAQAVMPINWTKF
LAQF---P------------------YNQIPSFYETFVQ----SSQ--PK----------------Q-------------AQSVAPKERQSLLKSFIRLQ
VAQVLGFSSSDVQQGFVELGMDSLMAVELKNRLQNNLGLAISPSLAFDYPTVAALTDYLL------------
>tr|A0A0Q3XMK0|A0A0Q3XMK0_ALLMI Uncharacterized protein OS=Alligator mississippiensis GN=Y1Q_005996 PE=4 SV=1
----------------------NDLMFENNWKEIFPVQSYSGEAPRVIVFADKLGIAQLLKKYLHHKSR---------YVMYEDWEIFL-EAK---KPEM
TAEHKKTEEGYCEVLFMWGIQKLSEELPGKLVAQ-LTKYCEAYRLIILALREKKSKCSVR---MITYRTTEKNVHINPGFALCGMTRTCIVEVSEIMFQM
IDISSSSML---D-ITALADVIVKCKDYPEIWINQGRIYTSEIRRTPFKDVNEAEKKMFKQNAVYIVVGGLTGLGFETVRFIAQNGGGSIAIFSRRSPN-
--KEKQKEIKALQDQYE--GSKIVSLQCNVVSASEVERAVQSVKIFSKRPIKGVFHSAVVLHDGHLEVLNMSHFEKVLSPKVAGVVNLHCATRGQELDFF
VCYSSVTSFLGNSTQANYAAANSFLDMFCHYRR-NSGLSGQSINWGALNL-GILLNQNIQNILESKGIDILQVHEIYDSLKKSLILNNPQAVIKLNFGTL
TNHVLSR-------------------IASLRSRFTTLISEEVGNQH--QL----------------SE------------QSAP-KNVSLIKSEDYVISL
VSHLMNANPLTMNTSLVSLGMDSMLVMTLQNRIFHERRVDIPHLADIPERHAVAFGLVLC------------
>tr|M7BY84|M7BY84_CHEMY Phthioceranic/hydroxyphthioceranic acid synthase OS=Chelonia mydas GN=UY3_05838 PE=4 SV=1
----------------------NDLLFENKWKEIFPTQTSLGEAPRVIVFADKLGIAQQLKKYLHNESR---------YVMYEDWETLL-EAK---SSEM
TAQHKKREEDYQEVLFMWGIQKLNDEFPSKVVAH-LAKCCEAYRQIIVALREKKSSCSVR---IITYRTTDRNVHLNPGFALCGMTRTCVIEVSGITFQM
IDISSLSTL---D-ISALADVIVKYKDYPEIWINQGRIYASEIRRTPFKDVSEAQKKMFKQNAVYIVAGGLTGLGFETVKFIAQNGGGCIVILSRSNPS-
--SEKQEEIKALQNQYE--GSRIVSLQCNVISHLQVEKAISSITIFPKSPIKGVFHSAVVLHDGRLEALNLSHFEKVLSPKVAGAINLHRATIGQELDYF
VCYSSVTSFIGNSTQANYAAANSFLDVFCHYRR-NCGLSGQSINWGALNL-GLLLNQNIQNILEFKGIDILQIHEIYEYLKKSLILNNPQAVVKLNFGTL
SNHVLSR-------------------IASLKSRFYTLISEELGSKL--DL----------------SE------------QSTS-LNISPINSEDYVTSL
VSYLSNTNLLTMNTSLASLGMDSMLAMTLQNRIFHERRVEIPLVKLLDPYTMSS-VLLLE------------
>tr|C4NCC1|C4NCC1_9CYAN Polyketide synthase OS=[Oscillatoria] sp. PCC 6506 GN=anaF PE=4 SV=1
----------------------DDWLYRIGWEVKPLAITKKSKAGSWLIFSDGGEVSNSLAELLNKQGDRCIFVPGSSFSLLEGDRYQINPAERQDFQQL
ISAIVKKESVCRGIVYLWGSDRNLE----ISDVTTALDLCTGALYLVQALSEIPHMPRLC---LVTHNGQPVT--QVEQSPLVGLARAIVLEHPELETVC
VDLNSRQA-K--E-IEMLVAELLFPE-EEQVAFRNEE----------------AHSPNINSSGSYLITGGLGALGLQVANYLVEG-ARHLLLVGRQGAAS
--PEAQAAVKQLEDK----GASVKIVKTDISQPDSVATLI---ETDI--PLRGVVHTAGVLDDGMLRNQTHKRFSKVMAPKVKGTWNLHQLTKEMPLDFF
VCFSSMTSVLGALGQGNYAAANTFIDALCHHRQ-ALGLPATSINWGPWASSGMATRLDLQNRWEAIGFGMIPPNQGMYLFGNLLKGQISQGVMPINWSKY
PVDS---------------------------TFLTEFRK----TTD--KK----------------K-E----------EEKAAEKDRHYPLLLAHVQSQ
VSKVLGYQKASVTEGFFDLGMSSLTSVELRNNLQNSLGCRLPATLTFDYPTVKKLVDYLM------------
>tr|A0A097PUK1|A0A097PUK1_9NOST Anatoxin-a synthetase F polyketide synthase OS=Cuspidothrix issatschenkoi LBRI48 GN=anaF PE=4 SV=1
----------------------DDWLYRIGWEVKSRVLSKTSKAGNWLIFSDGGEVSSSLADMLNKQGDRCIFVQGSSFSLLESDHYQINPAEPKDFQNL
LSAIVKKESVCRGIVYLWGLDQKLE----MSDVTTALDLCSSVLYLVQALSAIPPMPHLC---LITRNAQAVT--QLEQSPLWGLARVIVLEHPELETVC
IDLGSDQV-S--E-IEMLLQEMLFPE-EEQVAFRNGE----------------SQLAKIDSSGSYLITGGFGALGLQVANYLVEG-ARHLLLVGRQGAVS
--PEAQAGVKQLEDK----GALVKIVKTDISQPDSIPMLI---ATDI--PLRGVVHVAGVLDDGMVRDQTRQRFLKVMNPKVQGTWNLHKLTKEMPLDFF
VCFSSMTSVIGALGQGNYSAANAFMDALCHHRH-ALGLPAVSINWGPWATSGMATQLDLQSRWEAIGFGMIPPSQGMHLFANLLNAKAPQGAMPINWSKY
TVES---------------------------AFFTDFRK----NTD--QK----------------K-E----------EQKAASKEQRQPLLVAHVQSQ
VSKVLGYEKVSVSEGFFDLGMSSLTSVELRNNLQNSLGCRLPATLTFDYPTVKKLVDYLM------------
>tr|K9X6S3|K9X6S3_9NOST Polyketide synthase family protein OS=Cylindrospermum stagnale PCC 7417 GN=Cylst_6228 PE=4 SV=1
----------------------DDWLYRIAWEVKPSASAQRSKTGSWLIFSDGGEVSSSLADLLNKQGEQCIFVQGSSFSLLNDDRYQINPDEPQDFQKL
LSAIVKKESVCRGIVYLWGLERKLE----MSDVTTALDLSAGMLYLVQALSEIPPMPRLS---LVTCNTQAIT--KLEQSSLWGLARVIVLEHPELETVC
IDLSQHQV-N--E-VEMLVEEILFPE-EEQVAFRNGE----------------SQSAKIDSSGSYLITGGLGSLGLQVANYLVEG-ARHLMLVGRQGAVS
--PEAQAGVRQLEDK----GALVKIVKTDISQPDSVATLI---ETDI--PLRGVVHVAGVLDDGMLRDQTQKRFSKVMAPKVQGAWNLHQLTKEMPLDFF
VCFSSMTSVLGALGQGNYAAANAFMDALCHHRH-ALGLPAVSINWGPWATSGMATRLDLQSRWDAIGFGMISPSQGMHLFANLLNSKASQGAMPITWSKY
PVES---------------------------AFLTDFRK----STE--QK----------------K-E----------QEKAAEKDQRQALLVAHVQSQ
VSKVLGYQKASVSEGFFDLGMSSLTSVELRNNLQNSLGCRLPATLSFDYPTVKKLVDYLM------------
>tr|K9X335|K9X335_9NOST Polyketide synthase family protein OS=Cylindrospermum stagnale PCC 7417 GN=Cylst_4418 PE=4 SV=1
----------------------EDWLYEVEWVLQEHNTDKLDTKRNWLILADDQGIGQQLVARLRSQGESCTIIAANEYEQIAEHEFRLNPASPEHFQQL
CQAVP----HVHGVVNCWSLNAASIQ--TAADLVAAKISCGSTLHLVQAMLENY-PPNLW---LVTQGAQALEKVGLAQSPLWGMGQVIALEHPELNCVL
VDLDPNVT-D--A-DRVILSEISSQS-EGQVAFRDGKRYVARLVRTQP---D-YHGISFREDSSYLITGGLGDLGLLVARWMVEG-ARHLVLVGRSAVK-
--PAVRSQLEQLELS----GAKVVVAQVDVSDYEQVAQLLDSLPSSP--PLQGIIHTAGVLDDRLLKQQNWESFRRVMPPKVQGAWNLHTLTQKLPLEFF
VLFSSCVSMLGAVGQANYVAANAFLDSLAFYRR-SLGLPSTTINWGAWGEVGMAARNQVIERLNRVGMGAIASNQGLQVLEKLLLEQPIRGVIPLNWSQF
REKQ----------------------W-TASPFFTNFTK----GSE--QS----------------S-K-----------QQAVPVRERKALLVAHVSSH
LAQVLGWNPPDRKRSFFEMGMDSLTSIELRNRLQTSLGSSLPSTLVFDYPTLEELVDYLA------------
>tr|Q7NJ78|Q7NJ78_GLOVI Gll1954 protein OS=Gloeobacter violaceus (strain PCC 7421) GN=gll1954 PE=4 SV=1
----------------------NDWFYELAWQPLPLPAPATRPPGRWIVLSGNSALGADLATRLEAQGHSSVRVSEQFAILEPARHYALNGQKPEDFRRL
MREIV--NLPLLGVVHLWSLEEASGP-----------ALWESALHLVQALV--LAQAPLW---LVTRGTQALGQLAVEHNALWGLGRVIALEHPELWGGL
VDLDVEPGRDEAR-L---LAQLQAPDGEDHVAWRGEERLAARLVQTRQGR--AGAPP-AWESGGYLVTGGLGNLGLQVARWMVEQGARHLALVGRRAPS-
--PEAEAALAGLRKL----GAQICVLQADICDPHQAQAVLEHFDALP--PLRGIVHAAGVLDDGLLVQQNRERFAAVLAPKVQGAWHLHTLTRQIDLDFF
VLFSSVAGLLGSPGQGNYAAANACLDALAHHRR-ALGLPALSINWGPWAEGGMAAALSYQERIAAQGVSAIPVQRGLKALEWMLRQAVPQGVLPVQWAKF
-----VQPF----------------LPGRLPSLLRQIAREVQPRQS--AA----------------VPA-----------PSSLGFEPCYALLLTHLRGQ
LAQVLGLAPSDLEQPVNELGLDSLMTTELKRRIEGELGVSVPVVLLLQNPSLSQLAWKLA------------
>tr|I4HCX3|I4HCX3_MICAE Uncharacterized protein OS=Microcystis aeruginosa PCC 9807 GN=MICAF_5650001 PE=4 SV=1
----------------------SKNCYKVEWQLSPLNLKKPSQGEKWLIFNDNQGVGKALVTTLNDAY-ILVS-SGQTYQKLVSGHYQINPNNVKDFQRL
LQDIT---EPITKVVYLWGLDSDINSQP------SQTRSYASLLYLTQALAQCKTPPKLW---VITQQAQPVNDVKIAQTSLWGMGQVIALEYPNLWGGL
IDLEEKQP-SSQA-I---IAEITENLGEDRIAFRDHQRYVARLVPNKAIK---NINF-KKTEASYLITGGLGSLGLSLADWLIEKGANHLILTSRRALA-
--DHSQVKIKALEDK----GATIQVIAADVSDHQQTRQLFHQIENCP--PLQGIIHAAGVLSDRTIDKMDFHCFESVFNPKAAGAWNLHQLSQDLSLDFF
VCFSSISALIGSRGQIHYAAANHFLDGLMHYRR-ESGLTGLSINWGPWAKGGMATQ--YEEGLKRLGINPLQPNLALDTLDALINGNVT-MVAEIDWSKF
-----KTIV----------------AAKGRVAFLEALFKQDQDNFG--QT----------------V---------------KNPPHRRVTLLTTRLQQE
VAQVLGIHGLDTDQGFFEMGMDSLMSVELKHRLEGLFSVSLPSTFAFEYPTIGDVVQYFV------------
>tr|A1YBR0|A1YBR0_SORCE AmbH OS=Sorangium cellulosum GN=ambH PE=4 SV=1
----------------------AEHHYETEWRLAERERPAEPRRGGWLILDDQAERAAALQDYLEARGQTCVRVAADTYARRGARDYQIDPREPEHFARL
LGEQEDASSDRCGVVHLWSAHSSPAPTLE--SIQAQALGSISALHLVQALARAGWPPRLW---LVTQEVQAIKNTSVAQAPVWGFGATVALEMPELQCTL
LDLDATPNID-A--L---GQELLSASDEDRIALRGAERHVARLVPHVPEQ--APEPLSFKADATYLLTGGLGGIGLVVLEWMAARGARHFALLGRSGPS-
--ASAQPVLDRMRED----GAQVRTFSVDVADRERLRTVLAQITSMP--PLAGIIHAAGVGDQKMIPDLDGPSLQAIGRPKVDGSWNLHELTSELPLDFF
VLFSSVSSLFGSHGQSSYAAGNAFLDALSHHRR-ALGLPALSLNWTAWTDVGMATPIITSRYLATQGMGALSSREGVAALEQLFRASSAQGVVPLSIPSL
PRKPFYSVV----------------APPTAPTPTAQT---------------------------------------------ARPPGERQEAIEGTLREL
FARALRMPPKKLTEALQNLGVDSLIALELRRRIDEELGVKLQAAEIARVANVRELAQLVT------------
>tr|A7IE16|A7IE16_XANP2 Beta-ketoacyl synthase OS=Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2) GN=Xaut_1008 PE=4 SV=1
----------------------RDSLYHLEWHERPRASHSADAAGLWLLSGVPGAVADSLAEALRQRGVEVRLVGGDLAADIAA----------------
-------AAALRGMVLLEDGAGGTDVQE---A--VFEAVAGRALPAVKALA--EGGARLF---IVTHGAIACDGDDLVAAPLWGFGRVVGLEHAEIWGAQ
IDLDPADPAGSAA-A---ADEMLDLGADREIALRAGRRRVGRLARLPKPD---AGPVLLRPDASYLVTGGLTGLGLETARFLVARGARRLILIGRTALP-
--PRAVAAVRGLEQL----GASVRVEAFDVADEARLAAFLAAYEAHP--PIRGVVHAAGVIQDALLLRMTGEDIAAVMRPKVAGALALHRQTADLPLDHF
VLFSSASSVLGQVGQAGYGAANAFEDALAAHRR-AAGLPATAINWGPWADIGLFARL-LAERAGLSGVEPIAPEQGMAALDHLMARGETQLVLNADWAQV
PASARLELL----------------QAASAPD---------TPST------------------------------------SLMAPAERKAELRARLGAI
VAAVLRFDAKDHRRALTTLGMDSIMAVEIRNRVRRQFDLTPSIVDLFTGSVARLADW-LD------------
>tr|A0A074LK99|A0A074LK99_9BACL Uncharacterized protein OS=Tumebacillus flagellatus GN=EL26_14360 PE=4 SV=1
----------------------DSWLYEVQWEETPLPATPAEQQGLWLMLCDTAGVGDALADLWQQQGRTCIRLSGDSFQELGPLRFAVDPAREEDIRQA
LQIAYTLSEPLAGALHLWSLDIPIESMAQKERLLASRLALQSSVALVKTLSSDPLRTKVH---FVTRGAQAVDS-HVNQAPLWGLARSLPMEHPHLWGGL
LDLDPNASSA-Q------SAEWLNLTEEDQTAIRNGRLYNARLRTPDKAK---GEPTPISEDGTYLISGGLGGLGLETAKWLAKQGARHLLLLGRTPMA-
--PRSAATLLDLEQQ----GVQVETAAVDVSDAEQIRACLHQRRGVP--AVRGVFHLAGNAEGSLLTDLSAQTLSNILSPKLAGAWALHTALEGAELDCF
VLFSSASSLMPSPMISAYGAANASLDAFAHYRR-SLGLPALSINWGPFAQVGMAMQNTQNERQSFGALQLIQPEEALDGMRRLLAGSGSQAVFPINREMW
-----YQLY----------------ERNRTFPLLRALST-----------------------------A-----------PV--ASALKVDHVENYVSQQ
VANVLRLSVKDVQESMLNLGMDSLMLTELKNRIETDLNVSLPLVKLLQGPSVHQLSEMIR------------
>tr|A0A0H4WWB1|A0A0H4WWB1_9DELT Malonyl CoA-acyl carrier protein transacylase OS=Myxococcus sp. (contaminant ex DSM 436) GN=A176_002820 PE=4 SV=1
----------------------YDWTYAHAFEAT-AEELPAKSTGAWLVFADQGGLGAELAKALEQSGAQDVVRRGERFARDSSGHFQIRRGEAADVRGV
VDAVG--RVRIQNVAYLFGLDASPGGESE---------DVQALLDVVLAL---APGASIR---IVTRDAQRALPDAVSAASLIGFARVVPAEMPHLKTRS
IDLPRDASASQEL-VERLARELLA-EKEEEVALRDTRRLARRLNARPLPEWEAVDERLFDANATYLVTGGFGGFGLALARWMVAEGARHLVLTGRKGAST
--PEARQLVQDLEAA----GARVTPAAADVSSMDDMRALFARIADHP--PLKGVLHTAAVLDDAPLPDLNLQRIQRVMTPKAGGAWILHELTQERPLDLF
VLFSSVAALIGNPRQGNYVAANSYLDALAEHRA-ARGLAAVSIHWGVLGEFGMAQDEAVRTYLESLGLNPMAPATVLTALKRVLRLRTAQGLFDVQWAKL
GRAA---P------------------HLGKSARTEHLLG----------------------------SAQG-------GGQNGLSTDDRRPELEKFLVER
LATILQIPTREPQKPLSLLGVDSLLSMQVQRTIREALGIEIPALELLRAGSLVEVAGNLS------------
>tr|Q1D518|Q1D518_MYXXD Polyketide synthase type I OS=Myxococcus xanthus (strain DK 1622) GN=MXAN_4077 PE=4 SV=1
----------------------YDWTYTHAFEAT-AEELPAKSQGTWLVFADQGGIGAELTRELQRTGIQDLVLRGETFVRESNHRFQIRPGNAEDVRSL
VEAVG--RVRIQHVAYLAGLDARPGVESN---------DVQALLDVVLAL---APGASLR---IVTRDAQRAAPDALSATPLIGFARVVPAEFPHLRTRS
IDLPKSASASQEL-IERLARELLA-EQEEEVALRDTRRFVRRLSAKPLPEWEAADEPLFDANATYLVTGGFGGFGLALARWMVAEGARNLVLTGRKGAST
--PEAKQLVQDLEAA----GARVTAAAADVSSMDDMRALFARIATHP--PLKGVLHTAAVLDDAPMPDLNLERIQRVMSPKAGGAWILHELTQDRPLDLF
VLFSSVAALIGNPRQGNYVAANSFLDALAEHRA-ARGLAAISIHWGVLGEFGMAQDEAVRTYLESLGLNPMAPATVLTALKRVLRLRTPQGLFDVQWSKL
GRAA---P------------------HLGKSARTSHLLG----------------------------SAQG-------GAQSGLAPEARQPELEKFLVER
LATILQIPMREPQKPLSLLGVDSLLSMQVQRTIREALGIEIPALELLRAGSLVEVATNLS------------
>tr|A0A085WP69|A0A085WP69_9DELT Malonyl CoA-acyl carrier protein transacylase OS=Hyalangium minutum GN=DB31_6457 PE=4 SV=1
----------------------YDWTYEHVFEEARPEEAGAKSSGGWIVFADRGGLGAELVRALERSGVQDIVQRGEAFARESATRFQVRPGEAEDAGRL
VDALG--LARFRNIAYLFGLDASQVADAG---------DVLEFLRVVMAV---APGASLR---IITRDAQRAIPDSLAAAPLIGFSRVVAAEFPHLRTRT
VDLPQGASAAQEL-IERLARELLA-EQEDEVALRDTRKFVRRLKQRPLPEWEAADERLFDANATYLVTGGFGGFGLALARWMVTEGARHLVLTGRKGAST
--PEARQLVQDLEAA----GVRVTGVAADVSNRDDMRALFARLATHP--PLKGVLHTAAVLDDAPLPELNLERLQRVMAPKAGGAWILHELTQDRPLDFF
VLFSSVAALIGNPRQGNYVAANTFLDALAEHRA-ARGLAATSIHWGVLGEIGMAQEEAVRAYLESLGLHAMPPASVLAALKRVLRIRTPQGIFDVSWPKL
GRAA---P------------------NLGRIARTAHLIG----------------------------DSQD-------GAQSELSPEARQPEIERFLAER
LSLILQIPVRDPQKPLSALGVDSLLSMQIQGAIREALGVEIPVLELLRGASLVQVASTVS------------
>tr|Q50JA4|Q50JA4_STIAU Polyketide synthase OS=Stigmatella aurantiaca GN=mchA PE=4 SV=1
----------------------YDWTYEHIFEEAKPEEGGAKSSGGWIVFADRGGIGAELARALERSGVQDLVQRGEAFVRESDTRFQIRPGDAGDAGRL
VEALG--LARFRNIAYLFGLDASQVADAA---------DVSEFLRVVMAL---APGAAIR---IVTRDAQRAVPDSLAAAPLIGFSRVVAAELPHLRTRT
IDLPRAASAAQEM-IERLARELLT-EQEDEVALRDTGRFVRRLKSKPLPEWEAADERLFSADAAYLITGGFGGFGLSLARWMASEGARHLVLTGRKGAVT
--PEAKQLIQDLEAA----GVRVTGAAADVSNKDDMRALFARIATHP--PLKGVLHTAAVLDDAPLADLNLERIQRVMAPKAGGAWILHELTKDRPLDFF
VLFSSVAALIGNPRQGNYVAANSFLDALAEHRA-ASGLAAASVHWGVFGESGMAQGEAVRAYLESLGLHAMPPASVLGALKQVLRIRAPQGIFDVSWPKL
GRAA---P------------------ALGRTLRTAHLIG----------------------------DTQG-------GAQSGLTLEARQPEIERFLTER
LALILQIPVRDPQKPLSMLGVDSLLSMQVQGTIREALGIEIPALELLRGGSLVQVASTLS------------
>tr|C1F4N8|C1F4N8_ACIC5 Monooxygenase, luciferase family/oxidoreductase, short chain dehydrogenase/reductase family/phosphopantetheine attachment site 
--------------------DFAPLLYRRSWIEAAAPDSPADRTGTWLVLAHHSDLADGLSSFLQGVGTCKIIQPEEGQL--------------------
--HLTGPSFAWRGVICLLP--DI-----NT-------------ALTAQALTG--TNIPLWLVTQGAMPLPDSAPCSMKDAAVWGVGRALAVEQPANLGGL
IDLDPAGSS-----GYDLGQVLRSNGGEDMIALRGGTRYVARITRDDIPAKP-AKRLRFRKDATYLVTGGAGGLGQQVIQWLQSKGAENIAVLSRRMEAS
LRD-----------------G-ITTFRCDVTQHNEVAAVLDQIR-QSMPPLRGVFHLAGMLDDARLADLNMDRLQLAGAAKSGGAWNLHELLADTDLDHF
VLFSSMASLVTMPGQGSYAAANASLDALAHTRR-AVGKTALSINWGPWSGAGHAYGKRAHEALAALGIAPLAPELALAALNFLMERDVTQAGAQVDWQRL
---------------------F----------KNDPQAKSPLLSNFLPARQ---Q-----KA-----ATET---ALVQELGTCAP-GTRATLLIDHLTVI
LVDILRLPLVDSTQSFFHLGLDSILALEFTARISAGIGRPLPATTFFTHSTLDALAAHILNS----------
>tr|D6TD66|D6TD66_9CHLR KR domain protein OS=Ktedonobacter racemifer DSM 44963 GN=Krac_11725 PE=4 SV=1
--------------------DLSSWLYELRWEKQDFATNPEERSGTWLIFADRQGVGQRLAQHLQARGQCALVQAGSHYGALGLGRYQVQPQLNDVQRVI
SRVQETFATPLRGVVHLWSLSEQ-----TTAQTLEHDSALGVMQSLAQNTSA--QLPRLWLVTRDAQAVTDNAALAVAQSPLWGLGRTCAMEHPEIWGAL
IDLSSQEGIEE--GAQQLYASLLDTSREDQVAFRQGERYVARMVRSHDFVA---RDLHIRAQGSYLVTGGLWGLGFEVARWLAQKGARSLILAGRTQVPP
RSEWDRIPATDRGIRELEAEGVVHCVQLDVTDEAQLRAFLADHMRQGHPPIKGILHAASVWQVKPLINLDASALDAVFRPKVIGSWLLHTLFQESRLDFF
VSFSSGASLFGSAAQGNYAAAGAFMDSLAHYQR-AQGLPAISIDWGAVSEIGFGEGQRVHEYWESHGIQRISPRDVLAALELLIPQQAAQVGLKLDWQLL
---------------------R----------EFYPQIALPLVSYLVEDTSEQRT-----PT------STG---SGIDAILRATD-SERLSLLEQYLSEQ
VAAVLRVPRLDSDQPLTTLGLDSLMAIELKNRLEQALGVRVPIVTFLQGPSIAQFASQLLEQ----------
>tr|A0A0C2LZ49|A0A0C2LZ49_9CYAN Uncharacterized protein OS=Scytonema tolypothrichoides VB-61278 GN=SD80_31605 PE=4 SV=1
--------------------NLNDWFYEVQWEPTSPLNNQPEQLGSWLIFADSSGVAQKLAAVLTARGTCFIISP-SKDQVSEQGQFWIDPRPEQMHQFI
ENVLEPNQPLCKGAIHLWSLSDE-----MTSSSLQTSSVLSLLQALSNVKQS--VLPRLWLVTKGAQSTGESSLPAIAQTALWGFGKTCATEHSDLWGGM
VDLDPQATKDE--AASQLLSVISTQDVEDQLVFRHGQPYVPRLVQKRESVEN-ALPFSWRNNYSYLLTGGLGGIGLQVAQWMVEQGARHLILLGRTPLPP
RSTWTEVKEDTSAILNLEAQGAVYLASVDVADETQMSEMLETLKEQGCPPVRGVVHMAGI--GKLLQELDAERANQVLRPKVMGGWLLHRLFEKVDLDFF
ILFSSATHQLGSRGVGDYSAGNAFLDALADYRK-AQGLPAVSIEWGPWAEVGMARNDR----LARFGIGSITPEQGLEAMSRALRQNSPSVWIPINWSQL
---------------------L----------QMDQIAKSPFLSKLSRQVFSQQQ-----LK-----ASES---EILQKLKQHQP-NERFSVLTAYIQGE
VAKVLMLEKPDPQQGFFDMGMDSLMAVELKNRLEASFGASLPVTLTFEYPTIKDVVGYLVRE----------
>tr|A0A0J5X7D7|A0A0J5X7D7_BURCE Short-chain dehydrogenase OS=Burkholderia cepacia GN=VL15_08540 PE=4 SV=1
--------------------DFAALLYQRVWRPSSVEAAGASAHGEWLILADRGGVGAQLSALLESAGTCALHFADA-SA--------------------
--ALPALDRPLKGVIHLWSLADV-----AARRRASA-SVLQLVRALARAPSA--RQARLWLVTSGAMNVLDGESTAVAQAPLWGLGRAIAVEHAPLWGGL
IDLDPAQPS-----ATDIVQAVLAGGREDMIAFRGGQRHVARIARDNEF-VS-HRPVRFHPDAAYLVTGGLGGLGLRLAAWLAGNGAGKVVLLGRSKPSA
AAEKIL-----------QTLD-ARFIHADLSRRGDVADAIDEIA-RSMPPLKGVFHLAGVLDDALLARQDDDFFHRAGSGKADGAWYLHELTANLPLDHF
VLFSSMAALITMPGQSNYAAANSFLDALAQHRR-AQGKPALSVNWGPWAEIGHAYGRRAHEQLGALGVGTLSPELAIATLERLMASGVAQSGARIDWPTL
---------------------F----------RVDAPAGSALFSELAQPAA---Q-----PA-----QQET---ALLRQLHPCAP-RERLELIAGTLAKM
LAETLRLPDIAPEQSLLDLGLDSLIALELTDRLTKVFGRPFRATLFFSYPNLQALARYVLGE----------
>tr|Q0B1F2|Q0B1F2_BURCM Short-chain dehydrogenase/reductase SDR OS=Burkholderia ambifaria (strain ATCC BAA-244 / AMMD) GN=Bamb_6477 PE=4 SV=1
--------------------DLSALLYQRVWRPSSVDAAGASAQGEWLILADRGGVGAQLADLLQSAGTCTLRFADA-TP--------------------
--ELPAPDRPLKGIVHLWSLADI-----AARRRASA-SVLQLVRALARAPAA--RQARLWLVTSGAMNVLDGESSAPAQAPLWGLGRAIAVEHAALWGGL
IDLDPAQPS-----AAHIVQAVQAGGREDMIAFRGGQRYVARIARDNEF-VS-HRPIRFHHDATYLVTGGLGGLGLRLASWLAANGAGKVVLLGRGAPSP
AAEKIL-----------STLD-ARFIRADLSRREDVAQALGEIA-HSMPPLKGVFHLAGALDDALLTRQDDDAFHRAGSGKADGAWYLHELTADLPLDHF
VLFSSMAALITMPGQGNYAAANSFLDALAQHRR-AQGKPGLSVNWGPWAEIGHAYGRRAHEQLAALGVGTLSPELAIAALERLMASGVVQSGARIDWPTL
---------------------F----------RVDAPAGSALFSELAQPAA---Q-----PA-----QQET---ALLRQLHACAP-RERVELITDTLAKM
LAETLRLSDIAAEQSLLDLGLDSLVALELTDRLNKVFGRPFRATLFFSYPNLQTLAQYVLNE----------
>tr|A0A0D5EGX4|A0A0D5EGX4_9BURK Natural product biosynthesis luciferase-like monooxygenase domain protein OS=Burkholderia ubonensis MSMB22 GN=BW23_5767 PE=4 SV
--------------------EVAALLYQRVWRPSSGDAAGRSAHGEWLILADRGGVGAQVAALLESAGTCALCFADA-TP--------------------
--HLPAPDRPLKGVIHLWSLSDI-----AARRHAST-SVLQLVRALARAPSA--GQARLWLVTSGAMNVLEGEATAVAQAPLWGLGRAIAVEHAALWGGL
VDLDPAQPS-----AAHVVQAVRAGGREDMIAYRRDQRYVARIARDNEF-VS-HRPIRFHGDATYLVTGGLGGLGLRLASWLAANGAGKIALLGRGEPSP
AAEKIL-----------RTLD-ARVIRADLSRREDVAAAIGEIA-RSMPPLKGVFHLAGTLDDALLTRQDDDAFHRAGSGKADGAWYLHELTADLPLDHF
VLFSSMAALLTMPGQGNYAAANGFLDALAHHRR-AQGKPGLSVNWGPWAEIGHAYGRRAHEQLAGLGVGTLSPELAIAALERLMASGVVQSGARIDWPTL
---------------------F----------RVDAPAGSALFSELAQPAA---Q-----PA-----QQET---ELLRQLRSCAP-RERIELVTGTLAQM
LAKTLRLSDIAPEQSLFDLGLNSLIALELTDSLTKVFGKPFRATLLFSYPNLQTLAQYVLNE----------
>tr|I2DZ62|I2DZ62_9BURK Uncharacterized protein OS=Burkholderia sp. KJ006 GN=MYA_5597 PE=4 SV=1
--------------------DLSGLLYQRVWRPSSADATGASSAGEWLIFADRGGVGAQLAGLLESAGTCTLQFDDT-TP--------------------
--ALPALDRPLKGVIHLWSLADI-----AARRRASA-SVLQLVRALAGAAAG--PQPRLWLVTSGAMNVLDGEATAVAQAPLWGLGRAIAVEHATLWGGL
VDLDPEQPS-----AADVVQAIRAAGREDMIAFRRGQRHVARIARDNEF-VS-HRPVRFHRDATYLVTGGLGGLGLRLASWLADNGAGQVVLLGRSAPSA
EAEQML-----------RTLG-ARFIRADLADRDDVVQALAEIA-HAMPPLKGVFHLAGALDDALLTRQDDDFFHRAGSGKADGAWYLHELTADLPLDHF
VLFSSMAALLTMPGQGNYAAANSFLDALAQHRR-AHGKPALSVNWGPWADIGHAYGRRAHEQLAALGVGTLSPDLAIATLERLMAAGVAQSGAHIDWPTL
---------------------F----------RVDAPAGSALFSELAQPAA---Q-----PA-----QQET---PLVRELQACAP-RERLALVTDTLAKM
LAETLRLADIAPEQSLLDLGLDSLVALELTDRLAKTFGKPLRATLFFSYPNLQTLARFILDE----------
>tr|A0A066Y6T0|A0A066Y6T0_9ACTN Uncharacterized protein OS=Streptomyces olindensis GN=DF19_13900 PE=4 SV=1
--------------------PGRDLCYRTDWTAVS-AAPADTESGRWLVLADRAGTGEALAMALREAGSVEVVQADAASDAAHIR------------QAL
YGAL-ADGPL-KGVVLARPLLPD-----ATTDQVRAAAALALVRACLVDVPT--RCGRLWLLTRGAQPVGTVTAAGVLQAPVWGLGRVLAAEHPELWGGL
IDLDARTAPDE-AASAALLSAVLTGAVDDQLAVRDGSLLAARLVRAEMAAPA-PAAPDIDPDGTYLLTGGLGDLGLAMAGWLAERGARHLVLVGRRGVSD
DT-QREAVD------GLTGRGVVHVAVADVARADDVAALRAELEREGMPPVVGVAHLAGIARGAMLAGLDVEQLREVAEPKVAGAWNLHRVFGDAS--LF
LLVSALPAVFGGVGAANYAAANAFLDALAHHRR-GLDTDAVALGYGPWNGIGLAGGL---EQLSRLGVGSMAPAEALDVFGRVLARRPAQVTARLDWPEV
---------------------F----------TAVPSAATGQFAAFLEEFGGTSA-------------------HLLERCAQAAP-QEQRTIVGDYLTER
LAAVLQTGDIDPQVPVVEMGLDSLMALELRVRVKADLGVVVPMVRLLEGPSVEQLTDHVLGL----------
>tr|F8CI87|F8CI87_MYXFH Short-chain dehydrogenase/reductase SDR OS=Myxococcus fulvus (strain ATCC BAA-855 / HW-1) GN=LILAB_09175 PE=4 SV=1
--------------------PVDALTYALDWRPRTAPAPAAAGPGTWWVLMDGRGVGKALATRLEARGTVVRITAGATFQSLGPRDYQVAPDAAQLRRLV
EALLVAGGPVPRGLVHLWSLPAQ-----TTVETLEAETVLGLVQALV-SGAV--RPPRLWLVTRGCQPPAAG---ALASATLWGLGRVVSAEHPEVWGGL
VDLEPDAPGDA--SAAALCGVLLAPGGEDQFVLRGEAQAVARLARRRLPSGG--PATRLRADAGYLLTGGLGDLGLGMARWMVERGARHLVLMGRSPLPP
REDWAYVAPGSRAIRELEALGAVYPAAVDVADRDAVATFLRGYHAEGGPALRGVLHSAGVIQPATLMNLGADALHAVLRPKVAGAWVLHALLEDTPLDFF
VLISAVPGLVGGSGASNYAAANTFLDALAHHRR-ARGLPALSVDYGPWSEVGLAGGL---PMLERQGIGSMSPPQGLAALDRALTQPDAQLAASLDWPRF
---------------------F----------RAFAHATTPLLAEQVKEAGEGPA-----RS-----PEAG---ALQAALSEAQP-GARSELVREYLRTQ
VARVLARSRLDVNASLMSLGLDSLMSIDLRNRIESDLGVVIPMVNLLRGPSIAQLVDDVLPA----------
>tr|B4VZM3|B4VZM3_9CYAN KR domain family OS=Coleofasciculus chthonoplastes PCC 7420 GN=MC7420_2488 PE=4 SV=1
--------------------QYADWFYELQWQPQPLLSSPIREPGSWLIFADLTGIGQALAQRLEAQGICRLVYAAEEDAVAQEGQILLNPEPEAMQALI
EQM--ETLPPCRGVVHLWSLPEA-----TTLSSLDKDSTLHLIQALQRTNRS--QLPQIWLVTQGAQRIGEAVPPAIAQAPLWGVGRSLAMEIPQMWGGL
IDLDHDVSPVN--AANALFEQLWYPDQESQIALRCEQRYVPRLVPSPKQSIP-KQPLSLQSDGTYLITGGLGHLGLNTARWLVENGARHIVLMGRGEASS
---TAQQAI-----RQLEALGVVLVVKADVCNQADVVEVLEKIN-AYSPPLRGIFHAAGV--FHRFSDMTPDLIQSILAAKVIGTWNLHQITLGLKLDFF
VCISSITSLWGAEGLAYYAAANQFLDLIAHYRH-HLHLPALTVNVGALAGGGMHQGVALREIVTQIGLKYYEPQLFLKTLESSLVRGVAQPIVDIDWAIF
---------------------K----------QLYEARRRTLLKEIEVKSPQPVQ-----PL-----GKLG---QVLQQLKETSS-SDRDEFLITYLQEN
VALVLKLKQPSSEQNLTEIGMDSLTAMEFKNSIHQELGIDIPIVQFIGGTTIAALAAEINKQ----------
>tr|A0A0C1TWP4|A0A0C1TWP4_9CYAN Uncharacterized protein OS=Hassallia byssoidea VB512170 GN=PI95_57895 PE=4 SV=1
--------------------NLNDWFYELQWEATSLPNNQPEQQGSWLIFADSSGVGQKLAALLTARGTCFIISP-SEYHVSEQGQFWIDPCPEQMHQLI
ENVLGPNQPQCKGAIHLWSLSHE-----MTSASLETSSVLSLVQSLSNVKQS--VLPRLWLVTTGAQSIGS-SLPAVAQTPLWGLGKTCATEHSDIWGGM
VDLDPQATKDE--AASQLLNVICGQDVEDQLVFRQGQPYVARLVQ-RESVEN-ALTFSWRKDCSYLLTGGLGGIGLQVAQWMVEQGARHLILLGRTPLPP
RSTWSEVEEGSSAILNLEAQGAVYLASADVADETQMSEMLQTLKERGCPPVRGVVHMAGI--GKLLLELDATRMNQVLRPKVMGGWLLHRLFEKVDLDFF
ILFSSATHQLGSRGVGDYSAANAFLDGLADYRT-AQGLPAVSIEWGPWAEVGMARNDR----LARFGIGSITPEQGLQAMSRALCQNSASVWIPINWSQL
---------------------L----------QMDRFAKSPFLSKLSSQVLSQRE-----LN-----AIES---EILQKLKQHSA-SDRLSVLIAYIQGE
VAKVLKLEKPDSQQGFFDMGMDSLMAVELKNRLEASFGVSLPVTLTFEFPTIKDVAGYLAKK----------
>tr|E6U7B9|E6U7B9_ETHHY 6-deoxyerythronolide-B synthase OS=Ethanoligenens harbinense (strain DSM 18485 / JCM 12961 / CGMCC 1.5033 / YUAN-3) GN=Ethha_02
------------------------FYFRFAWRERALARQETAQKQPVLFCSDGSAQAEAIRTALVERGHAISTRFCKRFEKRANSEYSLGSSA-EDSTAF
LREMQE--GRWKKIVFFRASEKSRMARETLDAKETVENGLYRMLSLVKAIEKQSQKAEFIVVTDRAEEVTGEETLHPENAMYSSLGKTVNQECCRVKCRV
IDLDEH--T---S-PAAAVDEILFG-KDQAVALRNDRRLIQRLEPVHLHKTEN-GNDPFREGGVYVITGGSGALAAHVAKWIAARRGTHLILIGRSPIDA
AGGSQAATLETME-AIRALGSSAEYIQADVADERAAAEAFDRIRRTYG-RLNGVIHMAGITGNRMIVNMERSDFETVLAPKVFGTWNIDRLTQGDDLDFF
LLFSSGVSFIGETGLAAYAAANQFLNSFAQCRR-RT-RSVQAFDWVVWENQRMMDGYSRNVDGWFEQIRPNDALACMRE----LMPRR--------ESGL
LIGRLNRKNRY---EKSMFSHLP-------F-EVSEEVQRMVRITERAAAPDH--T----ETGRRA----------------ASPHPADPRTIEGTLTGI
FREVLGYQEIDIHDNFFDLGGNSILLKKLHQKVDEAFPGQVEVADFFAYTTVSKMAAHLAQT----------
>tr|W4BCK0|W4BCK0_9BACL Beta-ketoacyl synthase family protein,phosphopantetheine-containing protein OS=Paenibacillus sp. FSL R5-192 GN=C161_02760 PE=4 
------------------------HHYELGWVCEPERNSDKLSEGHVVIFMDEKREDRSLRKALQKQG-LIEVFDGPSFLQVSSGEYVISHQR-ESMEQL
WAHLGE--LMITQIIY---I--------------QQQQSFHPFFYLLQEMIRTSEPVDVVLLTNPIHSITGTEEVFPQAALMFGLGLAGRKEDSRLQCRS
IQVDAE--T---S-LQDILAELDHESDDYGVAYRAGTRYIQQFEAMDPSQYPK-RDYKIRNDGLYLITGGLGGIGLEIGLQLAERPGITLALVNRTALPW
DS-DALVKIRSVQ-QMEAAGATVLSYQADISDEASMRVILSELRQQYG-RIAGVIHGAGVAVGGDHPDRTIEEAECVLRPKVQGTQVVDQLTREDNPDFF
VMFSSIATLFSGPGQADYVAANAYQDAYAAYRN-RELDGTMTVNWSTWKETGAAAATGYG-DTLFKAMTNKEALAWLDQ----VEGRQ--------IERV
LIGQMSTDRGM----LKMIRNYP-------F-RLSPELENWIDSRLQRSSPKA--P----VTPRQD----------------AVADDGEYTPWEKQVADV
CQAVLGFNEIHIHDSFFELGADSILVKQMYAQLDRQYPGVLVVADLFEHPSVHRLGGYLADK----------
>tr|W4DBL4|W4DBL4_9BACL Beta-ketoacyl synthase family protein,phosphopantetheine-containing protein OS=Paenibacillus sp. FSL R7-277 GN=C173_20391 PE=4 
------------------------FMYRTSWSVNESEDPRPFEASIVLIFKDRSGYAGELASGLRNYGEVVEVEYGHGFQRAGDNRYIIGYSE-NDIFRL
LDEIQP--ASSLRIVHMATIGNS-----IAGEDEQPELGVYSLFHISKAIEALINKAELYLITQNANEITSFKEMNPGNAAFLGLGKAVNLENHRLQVSA
IDFDQH--V---F-INKIIDEMGARHTALDVAYREGKRYTGSLESVSINMVDDHHPVVYKENGVYVITGGTGSLGLLFAKHLASQAKVNLALINRSELPW
TASKALRKIEDLL-QIESTGASVTVYAGDVTIESDMSAILNDLRRKFG-TINGIIHGAGVAGRELVLDESRDSLERVMEPKVKGAVILDRLTEKDQLDFF
VLFSSVVALTGGIGVGGYTAANAYLDGFASWRS-RRGKRTLSINWPTWRHSVEHTLTTFDSKHLFKLLKVDDALRGFQA----AVSKS--------VSRL
IIGELNYSGNL----MYLERFLP-------I-EFSPEIKRKLARLEKRTKHRT--P----AVDKQA----------------AQ-GGNKCSTTEQRLSEI
WSRVLGVEEISIYDHFDDLGGDSIMVAQLFKELELEYPGRLEIVDVFSYSSISSMAQFLDRN----------
>tr|A0A0K1EJE0|A0A0K1EJE0_CHOCO Polyketide synthase OS=Chondromyces crocatus GN=CMC5_048540 PE=4 SV=1
------------------------------------------------------------------------------------------------ADGL
LDAIEDLPQPLHGVVYLRGVDAQLAPAPDTALATDASRVLAGALHVAQALARRERTPHLWLVTCGAQRLGATAPVAVAQAPLWGLGRTLALEHPELSCKL
VDLAPPSAAADAPLVSALA-ELLTDGPDEEIALREGTRHVGRLAQRPLSRPD---ATPIRNDGTYLITGGLGGLGLSAAAWLVGRGARHLVLVGRK-GAT
TPAQ-----IDALRALREAGAHVVTAQADVASRAQVAAMLDTAAVA-MPPLRGVLHAAGVLDDGTLLTQRRERLQRVFEPKADGAWHLHTLTRHLPLDFF
VLYASAASLVGSAGQSNYAAANAFLDALAHHRR-ALGLPAVSIDWSAFAEVGMAADLTASARNAHAGLRLIQPDEGTAILGALLDAGAQIGVIPLEGGQW
S-------------------------------RHPRAATS-----------TRLAELVRGGPRA--AAPAVSIDAA---LSA-APEEARAAMIERVVVEQ
IASVARPAQIERETALTSIGLDSLMGLELRTRLEAALTVRLASTLVWKHPTVAALAAHLHTE----------
>tr|A0A0D8BGD2|A0A0D8BGD2_9ACTN Polyketide synthase family protein OS=Frankia sp. CpI1-S GN=FF36_02636 PE=4 SV=1
------------------------------------------------------------------------------------------------GVRL
VDDLGDV-GEELQVVHLWSLTGAAEPDSVEAALRAQNAGCMSAVRVVQALVEARSPTRLWLVTRGAVQPTGTTPLAVGQATLWGLGRSLQQEAAAVWGGL
IDL--DPAA--EPAVAALLLEAADHRAEDQIALREGRRYVARLVHTRLPQPR---PAVLRREGSYLITGGFGGLGLEVARSLARRGARRLILVGRT-PVP
PREQWAGRRVAAVRELESLGASVTVESFDVSDEAAARAFLERHERECRPAILGVVHAAGAGDVAPLTDLEPDDLEWCLRPKAMGAWVLDRLFADRPLDFF
VLFSSTSSILSSPFVAAYAAANAFLDALALQRR-NAGRPGLSINWGIWERTGMAARGA-ATPGHSRGMGVLRPDQALRVLHRLLGHDLQVAVVPVDWSEW
G-------------------------------HRYQAVSL---------S-ALLSELLDAPAGAPAPGRRLPARAD---LLA-LPAQQRADALATRLLLA
TAVTLRPSAVGLDRPLIELGLDSLMAVELRNELEGRLGVSLPISVFLRGATVQALAERIVDA----------
>tr|J7H193|J7H193_9ACTN Type I polyketide synthase OS=Streptomyces sp. CNQ-418 GN=mpy6 PE=4 SV=1
------------------------------------------------------------------------------------------------ANGL
LNDWV--SEHPCRVLLLSGLDAPRDHTDAWGLEEYAARGDLLAVELVRLLAEREDEATVTLVTRGAMPAGDELVTTPSAHTLWGLGRVFALEHPERWGGA
IDVAPDPAADDTTEIERLV-ALERTSTEDEQALRGPDVYVSRVLPREPEPRA---PPPVRADGSYVITGAFGAIGLSLADWLARAGAGRLVLLGRT-PLP
DRTTWNRNRIRAVRELERLGVEVTVVTADVADEATMLAVFQELNGH-PLPLRGVVHAAGVSQPQFVRDVDADTYRAVWRPKVIGGWLLHQLTRTAELDFF
LGFSSIAATWGSQHLSSYAAGNAFLDGLALHRR-GQGLPALSVAWGPWELESNLFDEEVMNFLTSTGLFPLSQDQCLRLLGGLLSGPRQQVVCAVDWSIY
K-------------------------------PVMEARIE---------R-PILRGIEFSDDTG--DAETDALIKR---LRQ-DTPDARTERVTGLLRDV
VADVAGADTVERDADVMGYGLDSLMVMDVVRQCQRRLGVSVKASQLFERTTLGDWADLVDQR----------
>tr|A3R4U3|A3R4U3_9ACTN Polyketide synthase OS=Streptomyces sp. UC 11065 GN=dox24 PE=4 SV=1
------------------------------------------------------------------------------------------------AAAL
LERWRGAAATADRVVLLSGLDAPEEAADADTLVEYRDRTELTLVAVVQGLLAREDRATVSLVTRGTVPAPEQAVSSPFGNTLWGLGRVVALEHPEHWGGA
VDLDGSGPL--TDDIPGLA-ALLDVRAEDQQALRGGTRYAARLMPHRLGQRR---TPRVRQDGSYLVTGAFGGIGQVLSRWLAINGAGRLVLLGRT-PLP
PRADWDRERIALVRDLEATGAAVEVVAADVSDVGQMLPVMERLAVD-ARPLAGVVHAAGLSVPQFLRDITPADYDAVWRPKVVGGWLLHQLTEGADLDFF
LGFSSIAATWGSQHLSSYSAANAFLDGLAEYRQ-GQGQAALTVSWGPWELESNLFGEDVLAFLMSTALRTLSAPQCLKLLGALLAGPHQAVVCAADWATY
K-------------------------------PVMEARIE---------R-PLLRTLEVVEDYG--DPA-PVLEEL---ARA-GGPRERGRRLVGYLRDV
LGEVLSADGIEPAADVMSHGLDSLMVMEVVKRCKKDLRVSVRPNQLFERSTLEDWAELLGSE----------
>tr|K4R1B2|K4R1B2_9ACTN Polyketide synthase OS=Streptomyces davawensis JCM 4913 GN=pltC PE=4 SV=1
------------------------------------------------------------------------------------------------A-PD
LDDWLPDGVAPHRVVLLTGLDAPRDAADAESLTAFRDRAELAAVALVQGLTARAARTGLSLVTRGAVPALGQGVTSPFAGTLWGLGRAIALEHPEHWAGA
IDLDPQAGE--TDEGSALA-ALADTAAEDQQALRGEARRVARLVKFPLTARR---RPTIDRLGTYLITGAFGGIGQALARNLADSGAGKLVLLGRT-PLP
PRQRWNRERVDFVSALEETGVLVDVVAADVNDIEDMLPVIQGLATG-LMPLRGVVHAAGTSVPQFLRDIPPSDYDAVWRPKVVGGWLLHQLTEGLELDFF
LGFSSIAATWGSQHVTSYAAANSFLDALAEYRQ-AQGLTALTVSWGPWELTSNLFGADVVEFLTSTGLRMLSAPQCLRLLDALLAQGAQAVVCSADWSVY
K-------------------------------PVMEARAD---------R-PVLRTVEIDEGIG--TST-AVLQAL---EGA--DAAGRATVLTGYLQQV
LGEVLAPESVLPEADVMSHGLDSLMVMEVVKRCKGDLGISVRPSQFFERTTLEDWVRLLDTE----------
>tr|A3R4R5|A3R4R5_9ACTN Polyketide synthase OS=Streptomyces vitaminophilus GN=pyr24 PE=4 SV=1
------------------------------------------------------------------------------------------------ATEL
LARWRVPTDTADRIVLLTGLDAPEEAADAEALVEYRDRTELTVVSLVQGLLAREDKATVSFVTRGTMPAQRGDVSSPFGNTLWGLGRVVALEHPEHWGGA
VDLDPAGPL--TDDVARLA-ALLDVRAEDQQALRGDTRYVARLVPHSVTQRS---TPPVRSSASYLITGAFGGIGRALSRWLAINGAGKLVLVGRT-PLP
PRTDWDRERIDLVRELEATGALVEVAAADVCDPAQLLPVMEDLAVD-SRPLAGVVHAAGLSVPQFLRDITPDDYDAVWRPKVVGGWLLHQLTEGAELDFF
LGFSSIAATWGSQHLSSYSASNAFLDGLAEYRR-GLGQAALTVSWGPWELESNLFGEDVLAFLMSTGLRTLSAPQCLKLLGALLLGSEQAVVCAADWATY
K-------------------------------PVMEARIE---------R-PLLRTLQIVEDFG--AGS-PVLEEI---GRA-AGPRERVERLVGYLRDV
LGDVLSADAIEPEADVMSHGLDSLMVMEVVKRCKKDLRVSVRPNHLFERSTLVDWADLLSGE----------
>tr|A0A0F7ZT85|A0A0F7ZT85_9HYPO Uncharacterized protein OS=Hirsutella minnesotensis 3608 GN=HIM_07865 PE=4 SV=1
-----------------ATDRLDRFRFVINWQQIDTAASISGLGGSWGLLCPAGEVAWAEE-V----ESTLLLRSGLRQ---------LR---------R
ISGL-SDAQQLDGVLCLWDSDAKDVPLAARKL-------TAAALSQVQEAAR--GLFALPIVWVT-RNAVGTSSSGIAAAPLWGLMRTAQAENPNLKLRL
IDLDEG----PTGL--AALAPAIMLPAEPQCAMRQGKVLVPRLQPFRPRAGLPSQGPLVRRDGAVLITGGTGGIGRYVARWLAAHGVRDLVLISRRGPEA
PGA--EALVAELA----QLGAEAELVAGDVADVNSLRAILSRFGGS--RPLRGVIHAAGVLDDGVLSALTPQRCDTAFAPKADGAWNLHQLTQGMDLDLF
VLFSSVSGIMGAAGQGNYAAANTFLDALAYRRR-AEKQPATSVAWGLWTGEGMAANMSCLARYLRSGLDPLSPEDGLELLGQAARSGALTVAAAYNVQRL
QECHNDGHEL----PPLLR-------------SLIRTRHGRWQMRHGEGR------------------GQSESRGLRATLDSAA-PEEHPAITLVMVRLA
VAQTLGFSSVDVDVPLRDMGIDSLTAVLTRNQLAALTGLSLPAGIALQHPNLTTLSQFLLSQ----------
>tr|A0A0F5NHF2|A0A0F5NHF2_9MYCO Beta-ketoacyl synthase OS=Mycobacterium nebraskense GN=WU83_02785 PE=4 SV=1
-----------------TEAGLRDWMYQLRWQPASLSER--AEAGSWLILSDGGITAETLRDLESHSQTCALVEPGLDNQDFERNSYRLDPTQPEFRLLL
EDAFTDARPPCRGVVHLWDLLAAPAADTSESLDSATTLGPVSVLHLVQALAA--GWSAPPRLWLVTGGSQVTEPVSIAQAPVWGMARTIEHEHPELRCTC
VDLSVG----GGPE----FREVWADGRDGDVALRGGRRYVERLNHYDA--PEPTETVAFTEEATYLITGGLGALGLVVAKWMAEHGARHLVVMGRGGAS-
ASA--QESLDALR----AGGTEVIVAQADVAKADEVAAVIESIGESM-PPLRGVVHAAGIADDAILQCLDEQKLRKVMAPKVQGAWNLHALTSDAELDFF
VLFSSAASLLGPPGAANYAAANAFLDALAWHRR-AEGRPALSVNWGPWAELGFFTRSELQSYFAQYGVEAMSAADSLRALSSLLARSTQAVVLDIDWARW
QPDV----------QPPLL-------------AELGVAPSGDQPQ--GAT------------------ASGPGNGLSDELQGAT-PEERRRLLESYLCEL
AAGKLGLAP-DIQAPLNTLGVDSLITLELRMQVERDLGVVVPVTKLLEGPSVASLAEWLCDH----------
>tr|A0A0C2QT40|A0A0C2QT40_9CYAN Beta-ketoacyl synthase OS=Scytonema tolypothrichoides VB-61278 GN=SD80_11865 PE=4 SV=1
-----------------LTASIQDWLYEVQWQQLPRDVELSDKAGTWLIFADLEGVGQTLAKLRSQGHKCILVYPGNI-YSLKEGTWSINPYSPVFELLF
QEVLG-MELPLQGIVHLWSLEAEWALDLTSSLEQAQIFGVGSVLHLLQALII--SASPLPRLWLVTRGAVPV--PGVAQAPLWGLGKVVALEHPELWGGM
LDLAPN----STND----LAEISDSLGEDHIAFRNGSRYVARLVPKQQ--KQS-KQVALRSDGTYLITGGLGALGLKVARLLVSLGARQLVLLGRNTEK-
DSV--QSTLRQLE----ELGAKVIVQKADVSDEADMRNVLETIQATM-PPLRGIVHAAGILDDGILQQQSWERFSRVMAPKVRGAWNLHTLTKGLPLDFF
VVFSSAASLLGSPGQGNYAAANSFLDALANYRR-LQGLPGLSINWGPWAEVGMAASLARHQAANAMGLDSIAPELGLQVLKQLLQVSSQIGVLAVDWSVL
RQQLSVSHQL----PPLLF-------------ELFGKIKTQAE----TDV------------------LSAQQCDIVQQLQAAP-ASDRLALLTAYIQGE
VAKVLKFAPPDPKQNFFDMGMDSLTSVEFKNHLQNDLGRFFPSTLVFNYPNINALVQYLSQQ----------
>tr|B1ZYK8|B1ZYK8_OPITP Beta-ketoacyl synthase OS=Opitutus terrae (strain DSM 11246 / PB90-1) GN=Oter_1961 PE=4 SV=1
-----------------SGDPLAGYTYEVRWPAEPLGVPAAPAAGRWLVLGPAPQ---ELESFDANGQTLER-------AEAFRGDWR------------
-------------------GALFWAGDEP---G------ESEAARLLR---A--MQTANVPLWIATRGAVATARVRLDHAPLWGMGKVYALEHPERWGAL
IDLPAD----PTAV--D-AELLGHPAGEDQVAWRGGVRHVARLEPAPL--PPVSPLPVLRADAAYWVTGGTGALGLQVAQWLVARGARRLVLTARRSPG-
VTA--LARIADLE----KAGVTVRCLAADVAVEQDVRRVLAQVGAEL-GPVRGIVHAAGVVSRVSIAELTPEALADVLRPKLGGARALDAATAGHELDFF
VLFSSIAALWGAKGQAHYAAANAALDALAQQRR-ATGRPALSVGWGPWSGGGMAGPEE-QALLARYGVSPLDPAVALAALDRALGGTAQVAVARVDWAVF
KEFFELHGA------KPFL-------------ALVGGRREPAA----AGR------------------LE----AELAALATAA-PEQRRGGMEAFLQQQ
VAAVLGFKDPEVRQGFFALGMDSMMAVDLGRRLSQACGRTLSSTLVFDHASIHLLAAHLVET----------
>tr|A0A0E3ZRR5|A0A0E3ZRR5_9BACT Uncharacterized protein OS=Spirosoma radiotolerans GN=SD10_02295 PE=4 SV=1
-----------------IKDSLDEHVYLPQWVSEPLQSPANPSKRTWLIFADKKGVGTELARFEQNGHKTIKVFNGNCTFKIDESTYQLDGQNPDLQVLL
QDGVIHQ--QPNGFIYLWAADADTNARHSTAFP-----AYAQFLNIIRVVGL--PCTDHTPFWVVTQPVSSV--DSVSESPYWGFAKSAWLEYPQLKGGI
ITMDSQ----HGPA----VSELVSQQSEDSVWFDDENRRVYRLKKAS---PLSESPLTLDRTGLYVITGGLGFLGIKFLQWMVAHGAQHIVLTTRKNIPP
LAA--LKQVKAFR----QGGIDVKVVTLDIASHDQLREFIASVKLDG-LLLKGVVHTAGDSEYRSIETIDPQAISRILQPKIVGGWNLHQVTKDADLHFF
ICLSSITAIWGGKNQALYAAANQFLDGLSIHRK-ALGLPGLTVNLGPIAGGGMAGDST--TMFEKVGIQAMDAEAIFPVISKLIASASQAVLARIDWDKF
DAVYRMHAVS----PVLMM-------------AKVPEPKHRDE----GG---------------------QMASESLKKLEALY-PADRHTYLLELLNDK
VADVLGYRTVPLDIGLFDLGLDSIMALSLKESLEKEFQVKLKQTVAFNYPTIHRMANYLMSE----------
>tr|A0A0C2Q5J7|A0A0C2Q5J7_9CYAN Beta-ketoacyl synthase OS=Tolypothrix campylonemoides VB511288 GN=SD81_07450 PE=4 SV=1
-----------------VAASIKDWFYEIDWQVKPRQVD--HKPGTWLILADSKGVGKTLAELHSRGHTCILVYAGDT-YKTQEGTWSINPSNPTFKRLF
QEALG-SLMPLQGVVHLWSLEAELASKLTSSLEQAQTLGVGSLLYLIKELRF--NHESLPRLWLVTRGAVSV--PGIAQASVWGMGKVVALEHPELWGGM
LDLAPH----TTDK--SHLAEIEDSFGEDHLAFRNGNRYVAHLVRKQL--PEP-KKVVLRSDGTYLITGGLGALGLSVAQWMVERGAKQLVLIGRRIPS-
SKA--QETLRQLE----QKGAKILVVQADVSEREDVSRLLEEVKNSM-PPLRGIVHAAGVLQDGMLLGQTWESFHRVMAPKVQGAWNLHTLTQNLELDFF
VCFSSVSALLGSPGQGNYAAANHFLDVLAHYRH-GLGLPALTVNWGPWAGGGMAVEEL-QTRLSRMGIEGLQPEQAIAALESLLAANVQTTVANVDWSLF
KDLYEAQ--G----KRSLL-------------ELLGEQPQEAQ----LPQ------------------QSAQPSEILQRLQAAA-PSERISLLIAYIQGE
VAKVLRLESPDPQQGFFDMGMDSLMAAEFKNRLEVNFLTSVPVTLMFDFPTIKDLAWYIGKE----------
>tr|K9T4M8|K9T4M8_9CYAN Polyketide synthase family protein OS=Pleurocapsa sp. PCC 7327 GN=Ple7327_2136 PE=4 SV=1
--------------------NLEDWLYEVVWQPSKRQKTGQKTAENWIIFADRQGIGVKLAKALEEGDRAILIFLGQSYAISDEGHYQIDPTQPDDFQRL
FEQI-K---PCCKVVHLWGLEVTTDL----Q--QAQVLGCGSVLHLVQALIKARQLPKLWLATRGTQPVIDSTPIQVQQSSLWGLGRVIRLEHPDLPCKC
LDLDPSE---ESDDILTLLEELYSPDAEDQIAYRQGIRYLPRLMQRTSQDYGKSQPFMIREDGSYLITGGLGALGLQVARWLVEQGAKHLVLVGRSQSSQ
---AAQETISQLE----KAGARVCVIQADISNPEDVARIIVFYQKQSKIQLRGIIHAAGILDDGVLLKQTWERFERVMAPKVQGAWNLHVATQDLPLDFF
VCFSSIASLIGSPGQGNYAAANAFMDALVHYRR-GMGLPALSVNWGVWADVGMAALSAQNQALEQQGLSAIALQPGLQLLKE-LLQQAT-----------
--QVGALPV-----NWSI---FLKQLPETFFEAVTPKSE---------------------EKLVQ---PRSEFLQQLE----SAASSDRKTLLFDRVRSQ
VAKVLGFSLIEPQQNFGDLGMDSLMAVELKNSLQTSLGISIPLTSAFDHPTIELLTNYLAQE----------
>tr|A0A0A6P5Y7|A0A0A6P5Y7_9GAMM Uncharacterized protein OS=Candidatus Thiomargarita nelsonii GN=OT06_42525 PE=4 SV=1
--------------------DLSDWLYTVAWQSKVE---PQAEPDSWLILADQGGVGAKIAELLQAGEHCVQLYAKTSV----------------DFEPI
LKTL-QTEPFSLGIIHLWSLDVAGSEELLSAIEQAQRLGCESVLHLVQTLSRHEVSPRLWLVTQGAVPV--KSPLNVAQSPLWGLGKVIALEHPDWWGGM
LDLAPEMP--LD-AAKSLLTEIQNSQGEDQVAFRNGQRYVARLVRYRRP-----QAMPLDADNTYLITGGLGALGLIFAQWMAARGAQHLALIGRSNASH
----AREILDQLA----RNGTKVRVFQADVSCQVEMAKVLESIKI-SMPPLRGIVHAAGILDDGVLVQQNWERFMRVMAPKVVGTWHLHTLTQDLPLDFF
VCFSSSSTLMGATGQGNYVAANTFMDALAHHRR-ARGLPSLSINWGVWADAGMAALGSYDQNFAEYGIGKIATKQGLQVFGE-LLEQAV-----------
--QVGVMQV-----NWSK---LLQQFSPNLLSELVNQIHQVE---------------ETEQQPAR---QLEELRLQFK----KASPDERIARLTAYLQTQ
VANALRLNQLDVQQPLNNIGVDSLMAVELRNKVRKELGVDVPIVK---FMEGASVVDLATQL----------
>tr|B2J016|B2J016_NOSP7 Beta-ketoacyl synthase OS=Nostoc punctiforme (strain ATCC 29133 / PCC 73102) GN=Npun_F3360 PE=4 SV=1
--------------------TTDNWLYQIAWQRQNLEPASNKQPSSWLIFADQGGLGQKLAQLLTAGDRCIMVSAGAVYQQLQADRYQINLAHPEDFGRL
IQD--N---PCQGIVHLWSCDATT---------EPQLTSCGSVLFLLQAIYNAKALPSLYLVTKGTQTVGQLTPLQVQSATLWGLGRVIALEHPELHCVR
LDINPDA---PEDHIPSVAQELLVPSREDQIAYRQGLRYVARLVRSDVAEYGKPKETTIQADSSYLITGGLGALGLQVAQWLVEQGAQNLVLMGRRGVSP
---ENQPAIEQLE----QAGARVLVVTADVSQQEDVSQMLATL--ASMPPLRGIIHAAGLLADGMLLRQTWENFELVMAPKVAGAWNLHTLTKELDLDFF
VCFSSVSALLGSPGQGNYAAANAFMDALAHHRQ-ALGLPGSSINWGPWADAGMAALSSREQAWAAQGVQPIPLEPGLQILAK-VVQQLA-----------
--QVGVLPV-----DWSK---FTAQFPSDFLAEFTNAIS---------------------KV-TP---QVAELRQQLE----AAAPKQRPILLMNYVRSQ
IAKVLNLTEIDPKEGFLQLGMDSLMAVELRNRLQSSLGCSVPASLIFDYPTVDALVSYLIQE----------
>tr|L8LKG2|L8LKG2_9CHRO Polyketide synthase family protein OS=Gloeocapsa sp. PCC 73106 GN=GLO73106DRAFT_00011610 PE=4 SV=1
--------------------QSEADLYEIVWQIQPQQTEKDSRIRNWLIFAETEEFAVPLANCLKKRMQVILVLAGENYAQK-EEHYLINPYKSQNWERL
FREN-L---ENFGIIHLGG---SPSF----CPEKNQKLGCGSVLHLMQGLNLYNQCQKLLLVTRNTQKVEDEPDLNPEQASLWGLARVIRLEYPDLACIC
LDLEPTN---LEKDLVILQKEILQNDLEDQIAYRDGDRYVPRLTKKQKPQYGK----MLSADASYLITGGWGALGLKIANWLVQKGAKSLILLGYSQPSA
---EALAQIQTWQ----QSGVEVKPLQANLGDRQAIEHLFRDY-----PQIRGIIHSAGTIEDAYLINQNWESFERVFASKIAGTWHLHQATEKLNLDFF
VCFSSIVSLLGSQGQGNYVAANAFMDALMHHRR-QLGLSGLSINWGPWSHQGMAALE--QKGFSQRGIATIPPDVGLAILEE-LLLRYT-----------
--QVAVFSV-----DWKQ---FFLKSPPQFLSEFYAPTNLE-----------------KSS-----------------------TPVHNLESLKQYLQTQ
IAQVLGFSDIDPEQDFQEFGLDSLMIVEFKTKLEKYLAITLENSIISQYSSVNLLADYLLKE----------
>tr|A0A073C9W9|A0A073C9W9_PLAAG Pks5 OS=Planktothrix agardhii NIVA-CYA 126/8 GN=pks5 PE=4 SV=1
--------------------PELPDLYRLTWKSKPRLSAQTRKTASWLIVSDCPEFGVKLAKSLEEGDRCSIIHPENVSGKLQ-----------------
---------PCEQIIYLWSSDQTFDE------------TGASLLDLVQRITQQPTPPRLWIVTYSSPLS------KQTKNYAFGLAKVIRLEHPNLASIC
INFESFNLISLNQNFQTLLEELENPDEENQIVYRQGVRYVPRLNAYQPDNLGK-QDITIREDSTYLITGGLGALGLQVAQWLVTKQAKNILLVGRSEPSQ
---HAKNVIEKLK----NQGVTIQVIKADITDLEAVEKVIKPYTINQLPPLRGIIHAAGVLNDGILEKQTWERFREVLAPKVTGTWNLHTATLNLPLDFF
VCFSSITALIGSPGQSNYVVANSIMDGLMEYRR-LLGLPGLSINWGAWDEAGMAALSNQNQGLLAQGMKAIAPQQGLKVLDQ-LLSEIP-----------
--QIGVFSV-----DWSA---FIEQVPDGFLEDLISQDKAR-----------------KPEVNAN---QKLDFLQQLA----TASTSDRKTILSEKIRSE
LATVLGYSSINLEDNLSDLGMDSLMAVEFKNRLQNCLGSTFSLSSVFDYPDLEALVDYFLTD----------
>tr|A0A0A0WDX2|A0A0A0WDX2_9NOST PuwB OS=Cylindrospermum alatosporum CCALA 988 GN=puwB PE=4 SV=1
--------------------NWQNWLYQVEWRQQVRFISAAAQPKHWLLLCDNHGLGEQLAAQLRQGEICTLVFPGELAEKLDEQTFAINPQQPEDFQQL
LRDI-SHQPAIHGVVHCWSLDTVGADVLSSDLQGASQQSCGSTLHLVQGLVKASLSPRLWLVTRGAQS-VGDAVSGVAQSAIWGLGKVIALEHPELKCVR
VDLDPDV---LGDAAPALFAEVWADDAEDQVAFRNGLRYVARLIRSAQSQRGK-AELTLRGDRTYLITGGMGGLGLLIARWMVENGAKHLVLLGRSIPSK
---SAIETLEVLQ----NKGAEVMVVQADVTDVAQMTQVIAEIER-SHFPLSGVIHAVGVLDDGVLQQQTWERFARVMAPKVEGAWHLHQLTQNLPLDFF
VLFSSVASLFGSPGQANHAAANGFLDALAAYRQ-QQGLPGLSINWGVVADIGAAARQA--DGVKTKGMGTISPPQVLEILAQQLQTPAA-----------
--QVGVVPV-----DWSK---FIAQSTPWFFSDFQQ---TDD----------------SQE-QPS---QNSELRQQLE----VIPKNEQRAYLTNYLCTQ
VAKVLGLNSIDIQQGFFDLGMDSLTSVELRNRLQTSLGCSLPSTLTFKYPTVAALVDYLAVE----------
>tr|L8M2H9|L8M2H9_9CYAN Polyketide synthase family protein OS=Xenococcus sp. PCC 7305 GN=Xen7305DRAFT_00038270 PE=4 SV=1
--------------------TIEDWLYEVNWQPQNLDCKTNELPNNWLIFSQDGDMAWELEKQLP--GDSILVFPGAAFKAIAANQYQINPTQIEEFQRL
WQEK-S---SDSQSWGIIYLDLGANG----R--SPLQHGCAAILHLMQSSATEQ-LSQLVIVTQDTQFKT-----KNLSGAIWGLARTINLEYPKLNCIC
LDLEAND---IEQNASLILEELQHGNLETQIAYHNHQRHIPRLVRQNN-EYGKRGWGEIRNDGCYLITGGLGSLGLQVATWLVAEGAKHLILIGRNQLSD
---TARKTIAELE----ELEVTIKLEFADICDSLQLEQII-----QVQLPLRGVIHAAGILDDGLLKSLSWERFQAVLEPKITGAWNLHLATVRLDLDWF
VSFSSVVSVFGAVGQGNYAAANAFMDNLMSYRR-NLGLPGLTINWSIWDDVGMASLTPQQQQLSQQGLTAIAPEQGLKVLKR-LLQQVT-----------
--QSIVFPV-----DWSA---FLAQQPDNFFERFKTPTT---------------------TQEP----QATTFLQQLE----TTPESDRQQILQEHIREQ
IAKVLGFPEIDTQENFADLGMDSLMAVEFKNNLQASFGDAISLTATFDYPNIELLTEYIEGE----------
>tr|K9XRL8|K9XRL8_STAC7 6-deoxyerythronolide-B synthase, 8-amino-7-oxononanoate synthase OS=Stanieria cyanosphaera (strain ATCC 29371 / PCC 7437) GN=St
--------------------NLSEHLYQLVWFPNSNHNIYQVCVDHWLIFADRYGVGEKLAEELEKDRSCLLVFPKALEDCVENFRYSLDRNSREDWQKL
LKDV-Q---TNIGIVFLWSLDETEDF----V--TTQQQGCGSVLYLIQSLLENKQVAKLLLVTQETQAVANQASLQVQHSSLWGLGRVINTEHPQLNCTL
LDLDGFD---P---VTCVLSELNSIQQEHQVAYRQGNRYVARLDRYKLLDYGKTALTQINDQGSYLITGGLGALGLQVARWLVDKGARNLILVGRSKPNS
---EAKVIIQQLE----ETGAQIEVIQADIANLEAVNRIVRA---SSSPLLKGIIHAAGIIDDGLLQQLSWERFAKVISPKIMGAWNLHLATQNLPLDFF
VCFSSITSILGTFGQGNYAAANSFMDALMHYRR-SFGLPGLSINWGLWDDLGMAALNAEVKAFSDEGLETIELNSGLELLEQ-LLLQHS-----------
--QLAVFPV-----DWSK---FLSAKPENFFQLFKPKSE---------------------VKNQ----PISNLNPIF----------SNISAFQQHIQTQ
VAKVLGFSSVDVQENFADLGMDSLMAVELKNQLQTSLKIDIPLTITFDYPTVEALANYLFEK----------
>tr|F4PZ76|F4PZ76_DICFS Putative polyketide synthase OS=Dictyostelium fasciculatum (strain SH3) GN=pks29 PE=4 SV=1
--------------------PSQ-HIKQSFIQPKQSPNI--EPIDH-LLFITST-FTTKLIQQAGSMTKSIGLFSSDDL---------MNPD------LL
LDSM-EKNDKKVTIIYLESMEEMTID----SLTPKSTQY----LHLHLVIRQEQLPVKLIALRSGFFN---------------ECLTSIAREFGYKCGN-
FEFGTMVMTT----LDQIL-SNYSKLGELDYKLSTIQVMVERVLLSKNSKDGKRLSYNLDCQGTMLVTG-QSGISVECIYYCLAPKLTNIIVLSFSKPKF
EMH-IIKTNY--------PHVKLHYLQCDLGHYNSLKSSIQSLYQSRMEPVSVVIHCAVTYVS---EKISLGEHAVAMSAKAVGAWNLHNLFEELKLNHF
HLFSSVGQYLV-RESTSYGVANLFLDSLAMYRR-SIGLEATSVAWGSIGSTGRAVNQGSNAT-QGLGMSFLPLSCIYGVLRSSFANKTPI----------
-TRIMCASF-----LTKR---FIGSHQFLTFGHLLDEDLGV------------------T-AK-K-----------------KNNAQDGGNSIENMIIDH
IAEALSIELLSPDTKLKDYGVDSMVSIQIKTWLEQEFGKTQIHSQIS-NGSLNSIIQAVSNR----------
>tr|F4QFA2|F4QFA2_DICFS Polyketide synthase OS=Dictyostelium fasciculatum (strain SH3) GN=DFA_11170 PE=4 SV=1
--------------------PSK-FIKQSIYQPKNSPSN--ESFDH-LLFITSSSLLARLIEQSKQNNNNISLFSVDDI---------MDET------IL
LDSF-NKDNTQVAIIYLESIEEMKID----NLELKSMQL----IRLHQIIRKEQLPIKLITLIASQLN---------------HCLIPICREYQR--PSL
FMFDSISITS----LSQIL-ANHQHIGEKHVRLDTIQLSIERFVETPNAKDSKRLHYQLDVQDTLLITG-QTGVAVESLQYIISPRLRDIIVVSYSSPKY
EIN-DIKTKY--------QHVQLHYLQCDIGNYSQLASSIQQLYQSTIRPVKSVIHCANNYVFSLSDDLTLDVHHKALSAKAIGAWNLHNLFEELKLNHF
HTMSSMAQFTG-RESFSYSVANSFLDNLALHRR-SLGLSGTSIIWGSIGSTGRVAIKGSNEG-ELVGFNLLPLYTVYGILRASFINHTPF----------
-TVLQCASL-----S-TK---FVASSPNLLFCLSSDVIPK-------------------R-ST-N-----------------IN-GSQQQDNIENKILEF
IAETLSIELLNGDTKLKDYGVDSMIAIQIRSWVESEFKKSNLQAQIS-NGTINSITETINRI----------
>tr|F4Q303|F4Q303_DICFS Polyketide synthase OS=Dictyostelium fasciculatum (strain SH3) GN=DFA_08563 PE=4 SV=1
--------------------PSK-FIKQSIYQPKNSPSP--NRYDH-LLFITSSSLLKRLIEQSKKIQNNICLFSVDDI---------MDES------TL
LDSY-KD-GSKVVIIYLESVEEMKID----NLELKSMQL----IRLHQIIRKEQLPITLISLISSQLN---------------QCLIPICREYER--PSL
FLFDSVSMIS----LSQIL-ANHQHIGEKHVKLNSIQLSTERFIETPNAKDSKRLNYSLDIQDTLLITG-QTGVAIESLQYIISPKLRDIIVVSYSAPKY
EIN-DIKTKY--------KHLQLHYLQCDIGNYNQLALSIQQLYQ-NIKPVKSVIHCANNYVFSLSDDLTMDVHHQALSAKAIGAWNLHTLFERLKLNHF
HTMSSIAQFAG-RESFSYSVANAFLDNLAQYRR-NLGLQGTSIIWGSIGSTGRVADKGSNEG-LSVGFDIMPLHSVYGILRACFINDTPF----------
-TVLQCTSL-----SINK---FVSASPNLLFCLMSNVIPK-------------------N-TI-H-----------------NNLSASLQDNIENKILEF
ISETLSIELLSGDTKLKDYGVDSMISIQIRTWIENEFKKSNFQAQIS-NGTINSIIETINRN----------
>tr|F4QC64|F4QC64_DICFS Fatty acid synthase OS=Dictyostelium fasciculatum (strain SH3) GN=DFA_11312 PE=4 SV=1
--------------------PSQ-FIKKSIYQPKNSPSP--DNIDK-ILFITSTSTSTRLISQASSISKQVKSISSDDI---------SDES------SL
LDSY-QQ-GEKVVIIYLESLVEMNSS----NLDKKSMQL----IRLHQILRKEQLPVKLITLITGQLN---------------QCLVPICRDYDR--PSM
FSFDSISISS----LNQIM-ANSNHIGEKNIKLQVIQVNVERIIDAPKAKDSKRVHYQLDVQDTLLMTG-QTGVAVESLHYIIAPQLRDIIVVSYSSPKY
EIN-HINKHQ--------AHLRLHYVQCDIGNYDQLSSSIQQLYKSTIKPVKSVIHCANTYVFADADDVTIENHRQAMMAKAIGALNLHNLFEKLKLNHF
HLLSSIAQYSG-RESFSYAVANSFLDHLAQHRR-NCGLAATAIIWGSIGSTGRVASKLSNEA-SSIGAHMMPLSTVYGVLRSSFIDSTPF----------
-TSIICAAI-----KVDR---FLSETPNLLFCHLSSIVAK-------------------K-SN-N-----------------N----DNQDNMNDKIIEF
IADLLSIELLNGDTKLKDYGVDSMNAIQIKSWIEVEFKQSNIQAQIS-NGTINSIIENVNRI----------
>tr|F4Q8K0|F4Q8K0_DICFS Putative polyketide synthase OS=Dictyostelium fasciculatum (strain SH3) GN=pks30 PE=4 SV=1
--------------------PAK-QIKESVTQPKNSPSL--EKIDH-ILFITSSSLSTKLIQQANLITLDISFFSSNDI---------MDDN------QL
IDAY-CSSNKKVVILDISTLDPMNVD----NLVSKSMEY----LRLQQIIRREKLQIKLISLRTSTLN---------------DCLSPISREFNFKSGSL
FSFESLALSS----IKQIL-SNYQALGEGEFKLEMVQVNVERLVYARDVKDSKRHSYELDVQGTLMMTG-QTGVAAECLYYLIAPKLSNIIIVTHSKPKF
EMH-TIQSQN--------PHLTLHFIQCNISNYDQLRLSVKQLYETTIEPVKVLLHCANQYMATTADDITLEDHQQALSAKAIGAWNLHHLFEELKLNHF
HLFSSMAQYLV-KGNTSYGVGNAFLDGLARHRR-ECGLEGTAIAWGSIGSAGQVAHQGSNAS-SSNGLILLPLSYVYGVLRSSFINQTQL----------
-TRTICGNV-----SLKK---FVESLPFLSLTQYLT---I-------------------S-NK-K-----------------SMMGGVDTNSNENKIINH
IAETLSIELLSPDTKLKDYGVDSMVSIQLKTWIDQEFGKTQIHSQIS-NGSINSIIETIQRS----------
>tr|F4Q2B0|F4Q2B0_DICFS Putative polyketide synthase OS=Dictyostelium fasciculatum (strain SH3) GN=pks39 PE=4 SV=1
--------------------PSKDIIKQSIFQPKNSPLL--GEYDH-LLFITSSSLSDRIIKQSTLVSNSVGVFSSDDI---------MNES------SL
LDAL-NNNSGKVVIIYLESTEEMKAN----NLELKSIQL----VRLYQIIGKEQLSVKLITLISGQLN---------------QCLVPIRREYDR--LYT
HQIDSVTICS----LAQIL-SNNHYTGEEEFKLGKIQVLVERLVHGSDQKDSKRLDYHLDVQDTLLITG-QTGIAVESLYYIISPKLRDIIVVSFSSPKY
EIN-HFNKSNNNNN---NTQPNIHYIKCDVGDYSQLKSLILDLYKQTIKPVKTVIHCANIYQTVRAEDINIESHHQAMSGKATGAFNLHNLFEELKLNHF
HLLSSFAQYIP-TNGLSYSIGNAFLDGLARYRR-ERGLEATSIAWGSIGQAGKVAEKVVDLT-NSFGFTMIPLSYMYGVLRSSFINQTPF----------
-TNLLCVDI-----VTKK---LVTNQPNLINCHFLDIGAN-------------------I-KN-D-----------------S--TLSNTDSIEIKILDY
VSEILSIELLSGDTKLKDYGVDSMVSIQIKSWIETEFKSC-SQSQIA-HGTINSIIETIKRN----------
>tr|F4QC62|F4QC62_DICFS Putative uncharacterized protein OS=Dictyostelium fasciculatum (strain SH3) GN=DFA_11310 PE=4 SV=1
--------------------PSR-YIYKTELQPKNSPSLINNQLDS-IIFITSSSIQQRLIEQANNMRENVTLFSSDNL---------INDDDNN---LL
LES---Q--KRSLIIYLESLEEMTSD----NLVVKTMQH----LKIHQIIRKAQIEVRMLTLIDSPLN---------------ECLIPNCREYQDQGSVL
FEFDSIPISN----LDQLL-SNSSLLGDKEFTLKDLQVMVEREFKSPLSKDYKRVNYTLEIQDTLLITG-QTGMSVECLQYVISPQLRDIIVLSFSAPKY
EIN-QTKMKNH-DG---SSTLAIHYIKCDVGNYSALESSIVELYKTAIKPVKTVIHTANFYHVLGADSINLENHNEAMSAKAVGAYNLHNLFVKLQLCHF
QMLSSVATLIS-KGNTSYGVGNAFLDGLAKHRR-QCGLAATSINWGSIGSTGKVSDKGARTN-GSLGLSMLPLSVVYGVLRSSFISQTPF----------
-TQLRCFDA-----NLKH---FVSAIPYLRFTPLVTFDSTS------------------A-TK-Q-----------------NNQGVGGNDTIESMVIDQ
ISDILSIQLINTDTKLKEYGVDSMVAIQIKSWIEGQFNKLNLQSQIS-NSSINMIIDLIKK-----------
>tr|T2LFB8|T2LFB8_9GAMM Beta-ketoacyl synthase-like protein OS=Halomonas sp. A3H3 GN=HALA3H3_970020 PE=4 SV=1
-----------------------HFSYLVELTPAPLHAETAQ--RRHLVV-ASEALAANLVEALQSGAS-----------ALL-----VSQSAPAELLPA
LAQM-AQAELTLNVVDLRGLG-----A---NSTEAQTARCN--HALQWTLALEQLAASLWLVTNGVSDLPASATDAPGDAVLWGFGRSLANEAVGHSVYL
LDIPAAV---SEPALHAWATLLTQPDSENEALIDNQGHRFATRLRTLPAMPGKTAAMQLSADASYLVTGGLGGFGLRTAQWLVEKGARQLILLSRSGPTS
E--EAQAAIASFE----QQGVTILAAACDITDRTALADVLERAKG-ELAPLRGIVHAATVIDDGLIRNLDAERIQKVLAPKIDGARHLDALTREAELEFF
VLYSSATTLFGNPGQANYVAANHWLEAFAANRR-AAGLPATCVRWGAIEDVGFLANTRTRDAQERLGGSALRSDDALKVLEQ-MLLAGP-----------
--SLGVLEL-----EWGA---LARFLPTARFNEIARASDDD------------------G--SAD---ADDDISALLA----DLSPEELHSTVTDLLRAE
LASILLIDKLDIHRSVYDMGFDSLMGVELMTAIENRLGVQVSVMVLSEASTLDKLAGVLIQK----------
>tr|A0A0B2B9T1|A0A0B2B9T1_9ACTN Beta-ketoacyl synthase OS=Mumia flava GN=LK11_42005 PE=4 SV=1
--------------------LPARFVYRLEEVPLPGDVNTLARSEQWLVMHAAGSFGGRLADALARGYPADIVDVTHAADAIA-----LPAGQPAHVV--
FCAT-PLAG-----------------D---DLMAAQRNGVIALAELVRALGMQ-AATRLTVVTRGGA--AGAANAHPEQATLWGLGRVLANEHPELACRL
IDVDRAA---DRIP-DALIRELTGAAIEEEVVLGVHGRQVPRMLT----APGKAGSLALDPHGTYLVVGGTGGLGFASARWMVERGARRLTLASRSGELA
A--AAREEVERWRA---TLGVTVDVVSCDVTDAAAVDAMIEAIVR-RGGPLKGVLHSAMSIDDGLVRNLDDARMAAVLAPKVAGAWNLHRATRALPLDLF
VVYSSATTYLGNPGQSNYVAANTFLEALVEHRR-AAGLPGTFMAWGPLEDVGFLAHADTREAQSRIGGASITSDEAMVALER-VLVAAA-----------
--GEAVVRL-----DWHA---VARGMPAARYSLLQSHAKGG------------------D--ARD---GGTQLREEVL----ALPRDEAIALVARTLQGQ
IARILHMTRIALDKSVLDMGMDSLMGMELGLAVEEAFEVKLSVMAIAEGASVTTLAGRIVDS----------
>tr|Q4C7P4|Q4C7P4_CROWT Beta-ketoacyl synthase:Acyl transferase region:Zinc-containing alcohol dehydrogenase superfamily:Phosphopantetheine-binding OS=
--------------------SLENWLYGVKWNKQPLTANINTEAKNWLILGDRQGIASHLVQTLESGENCIVAYSDSHYQQIGAKDYQVNPQNEQDISRL
LEKK-Q----FDQIIYLWGLDDPSEEDLIDTLETGSENHCRSILQLIQNSY--NKPPRFWLVTKGVMATKNDPVVSITQSSLWGLGKAISLEHPEFNSVC
VDLEINTE--LKQQVKVLLEEINANSPENQIAFSKNTRHVARLVPQKLSQRGKQSSLKFSEDGTYLITGGLGDLGLLVAQWMIEKGAKNIVLMGRNEPKL
---EQKQKIKALE----TLGGNITIAQGDVSNKEQLATILKAISPSPLSPLKGIIHAAGVLDDGVLKQLTWERFNKVMSPKVQGAWNLHNLTKDKPLDFF
VLFSSAASLLGSPGQANHVTANTFLDTLAHYRR-SQGLPALSINWGLWSDIGAAARQV-----KRQGVGAIAPDEGITILEM-LMKDLA-----------
--QVGVVPI-----KWDE---FLQIEQNIFFSNFKQ---QKA----------------TST---N---SSSNFLQQLE----DIPPEEKENYLREHIRAE
ISQVLGFNDVDMEIGFFDLGMDSLTAMEFKNRLQNTFACTFPSTIAFDYPTGDALVSYIATE----------
>tr|A9AUI9|A9AUI9_HERA2 Beta-ketoacyl synthase OS=Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785) GN=Haur_1873 PE=4 SV=1
--------------------IGDDLFYSVKWLPDQASQPPHQALGSWLILGDQQGLGQELAQLFQAGESSVLVTPADNYEQLDEHHFQLNPRELSQFQQV
LQAN-L---PYRGVIHLWGLDAVDTEELLTTLSEAQGLGCDAAVQLIQAVVELDELPRIWLVTRGAQSVPEQATIAVAQAPLWGLGRVLATEHPELMGAL
IDLDPTK---SSNEAFELFQAITTGIDGEQLALRQNQRYLARLMRDSFD----KQGLGLRPDASYLITGGLSGIGLEVARWMLQQGARRLILLGRTTIPD
RSASRIAAIKELE----NLGASIHVASIDVSDEEQLAMFLAEYQQQGWPPIRGVIHSAGLIKDQLLMRMDQETFDVVNRPKIFGSWLLHRLLRKSPLDFM
IMFSSATSIMGMFGQANYAAGNAFVDALAHFRR-SQGLPAMSINWGLWAETGIVALKM--NDLNQSGVIGMTSEQGLEVMAQ-LFQRPI-----------
--QIAPMLT-----DWQR---WQQAYPQTFFKSHFELVNAQIA-------------RQTDQVAVP---SQSGIVQELL----LLEPEQRQTRLEMHLRDV
IATVLRLDRIDLDQPLNRLGLDSIMAVELKNRIEVDLGVSLSIVELLQGASIAQLTQRILPS----------
>tr|B1WWV7|B1WWV7_CYAA5 Polyketide synthase OS=Cyanothece sp. (strain ATCC 51142) GN=cce_3078 PE=4 SV=1
--------------------TLDNWFYRVKWQKQPLFSNIDADGKNWLILGDRQGIASQLVQILESGKNCIIAYAEKTYQQLGQQDYQINPQRPQDWQRL
LSKQ-S----FEHIIYLWGLDTPSEEDLLETLETISENHCLSILHLIQHSY--TNPPRLWLVTKGTIATDDDLISGIAQSSLWGLGKAIALEHPEFNCVC
LDLDANTP--LKQQIKLLLDEISSNSPENQIAFRKGTRHVARLVPQKLPQRGKASTLKFREDGTYLITGGLGGLGLLVAQWMVEKGARNLVLMGRNQPNT
---TQKQKIQALK----ALGANIIVAQGDVSNQEQLEAILQNIETASSAPLKGIIHAAGVLDDGVLKQLTWERFNKVMSPKVQGAWNLHTLSQDKPLDFF
VLFSSAASLLGSPGQANHVTANTFLDTLAHYRR-SQGLPALSMNWGVWSDIGAAARQV-----NRQGVGAIAPSQGIASLEQ-LMKDMT-----------
--QVGVVPI-----NWNK---FLQFNPNIFFANFKP---KKA----------------KLA---E---NKNNFLQQLQ----TIPPEDKRDSLKDYIRSE
VAQVLGFNDINMETGFFDLGMDSLTSMEFKNRLQNSFGCTLPSTLAFDYPTGEALVNYLATE----------
>tr|B4WGT1|B4WGT1_9SYNE KR domain family OS=Synechococcus sp. PCC 7335 GN=S7335_1374 PE=4 SV=1
--------------------TPHRWLHELVWQVKTHDQPSNQNAKFWLLFSDRQGVGKQVAKELRNSDRVIEVMLADTYQLDLTDTCRLNSLDPAAFGQL
FDDV-PTLVLACQIVYLWALDANRII----GDLLDQERICGGLLHLVQTLAKFP-KVRLWLLTQNAQSIA-PSPLDLQQSPLPGLARTLRLEQPELGCTS
IDLPQPF---TDRAQDLLVQDLCAPGPEEQIAYRQDNRFVARILPQNKASYGKPHQPLINPQATYLITGGLGALGLKLARWLAEQGARHLVLMGRRSPSE
---SARQAINELQ----RSGIAVETIQADVSNLSALESALSPYLTLLKGPLKGIFHLAGTLEDSLLINQSWQNFAKVMKPKVMGAWNLHTLTKSIDLDHF
VCFSSIVSVMGSLGQSNYAAANAFLDSLAHHRQ-SLGLPALSLNWGPWAEAGMVALDERSKKMVEQGLTQILPEVGLDLMSQ-LMQQKA-----------
--QIGIIPI-----DWAT---FMATASGQLLSAVKPVTA---------------------PQPR----IQSGVLSQLAKCSPEERLRQRAQILTGYLRTQ
LAKVMGFSAIAPDQQFGDLGMDSLMAVEFSNRLQKNLNHPIPQTLAFDYPTIDALANYLSHE----------
>tr|A0A0P8A0W8|A0A0P8A0W8_9CYAN Polyketide synthase module OS=Phormidesmis priestleyi Ana GN=HLUCCA11_05235 PE=4 SV=1
--------------------SKTQWLHEIVWRSHPLPQTHKLAQKRWGLCGEVLGVSSI-VALLQEGQPFEALYQA------------------------
------EDQVFDGVVYTLPTRPLPTDVTDIALVTATETICRQALETIQMLAKQPNSPRLYFVSTDVTP-----ETQLVHAGLWGLLHTAQLEHPGLRCTY
IQAETP---------EQIVAELLSDSVETQVIYRDRTRHVARIENYPEESTGKPSAVKFHTDASYLITGGLGGLGLVMAEWMAKQGARRVILLGRQAPDS
---TAQIVIDRLI----NNGISVEVMSADVADSIAMATALDRINQATDHPLRGVIHAAGVLDDGLIQQLTWENFEPVFAAKATGAWNLHTLTQNNELDFF
ILFSSAAALFGSPGQANHAAANAFLDGLAHYRN-QVGLPALSINWGAWSTVGSALYQQQ-GIEHFPGIETIDPKSGIAQLEK-IWSTTP-----------
--QVGIVPI-----DWQV---FLTQNNLQFQTQAQTHAQTHAQTHAQTH-GLMAERNRGVTSPSS---ISSSLLIDLT----HATPEQKRERLDLYLCNQ
ICKTLGFSELDRQTGFFDLGMDSLTALELKNSLQTDLGLVLPSTLAFDYPTVEALLDYLAAQ----------
>tr|A0A0G2IGJ5|A0A0G2IGJ5_9PEZI Putative lovastatin nonaketide synthase OS=Diaporthe ampelina GN=UCDDA912_g00221 PE=4 SV=1
--------------------GAREICFNLEWKPDVDILEDDAISRVFIAHTADAAVAAAVASAVGGTRHAVSVVRFADLA----------------QH-R
LKN--TC-----CIVAMETTAPFLAS----SF---SEAE----FGLLRQLLT--TAGGLLWLTLDPHE-------DPRMALIAGLLRTVRWERDLDGSDL
LHLP--CAELV---ASSVVGVSLSPDRHADYLVDGGFVQTARIVAAPAVGPGKPAPTRLRPDATYLLPGGAGGLGRSIARWMAAQGARNLVFLSRGGDGA
A--TTRELLAELG----AAGVRAAALRCDVGDEAQLVAALGEAARLGFPRVAGVVQGAMQLRDSAFEFMSHAQWEECLGPKVQGTWNLHRHLP-ADMDFF
VMLGSVAGLVGNRGQSNYAAGNTFQDALAVHRR-ARGLAATCIDLCNIMSVGFVANQETLNKLFFFAHDGISEDEFLSLVEFHLDAAAGGEG-------L
APQVGVGLA-----PLSV---FKLPEPTFLFRQLRSAGGEAGG--------------AADGAPDQD-GAAVSVTNALKF--A-ESPEAAAELICGALVRR
LSRTMRIPDVDVGKPIHVYGVDSLVAMEIRNYLASECGSEVSVLEIMGNKSIEALSG---DI----------
>tr|G7XBG1|G7XBG1_ASPKW Fatty acid synthase S-acetyltransferase OS=Aspergillus kawachii (strain NBRC 4308) GN=AKAW_02699 PE=4 SV=1
--------------------KGSKLATHLQWKPDIRFMS--------LLCTSYQTWMQSLAVCLSSG---------YDVH----------------WC-T
FEE---DLPTE-NVIAVLDFDRPFLY----DI---SQAT----YTKIQSWLA--SVKRLLWVTHSMQIE----CKDPRYCLILGLTRTLRYELNVDVG-T
CEIDLFEEAP------VVMGG--QTIRDFEFILHRGVGHTGRAAITKVTTIGKQAGFSFSSTSSYMLVGGLRGIGRAVVRWMVEHEARNFTFLSRSAGNH
E--EDQQFAKELE----SQGCRVVMVAGSVTDPDTVQRT----IQQAERPVA---------GDQLFDKMSYEEWTTSLATKVQGTWNLHNALQDHSVDFF
IVFSSAVSMIGNSGQANYAAANSFLDGFVQYRR-GLGLPASLVSLGPVDEMGLMSQPELLSKQLSH--HMMGEGDVLKAFQLALLSADGLSSR------R
PAVVVAGLS-----P-AV---V-TSDPWLRFSSLPKG-TDMSN--------------AGGVDDEQ---LQRKFASARDDP-TSLIDGSCEALIIEKLGK-
QIAMHNGLEEMGVDQYSSLEVDSLMSLQIKHWLGRKVEVEVSLGDIMKARTVGNIAKLVTEY----------
>tr|A0A0F4YNJ2|A0A0F4YNJ2_TALEM Lovastatin nonaketide synthase OS=Rasamsonia emersonii CBS 393.64 GN=T310_6161 PE=4 SV=1
--------------------RTAKFCHTVEWKPDVDLLK----------------------------------------S----------------NR-D
LRN--THCV------SLMELERSVLA----DP---TEEE----FANIRHLLS--TCDGLLWVTGDFTS-------NPELNMIAGLIRAVRWERDLEGPNT
LAISDPRPSIM---VQAILKSNTDKD-NGEYVFQDGVFFTNRLVDATEMAPGKPVQMKFEEKASYVLAGGFGGIGRSIARWMASRGAKNLIFLSRSGAAS
S--AAQETIQELE----SRGVTVRVFSCDVSDKDRLVAVLEE-CKTSLPPIRGCIQGSMVLADKIFENMSYEKFRAATRPKVQGSWNLHACLP-RDMDFF
ILLSSATGLVGNRGQANYAAGNTYQDALAAHRV-SLGLHATSLDLGTLLSIGYVANRQLLGHYVASLLGSVREEEIHSVIEYCVKPT-GPSK-------R
PIQIASSVT-----TAAE---YRMPTPSWLFTQLASTSSSATT--------------GPGGEESA---SGLNIASLLES--A-TSLADAAAVVADAIRTK
LSKLLNISNIDPSKSVSSNGVESLVAVEFRTWLAKVLAADIPLLDILGTMPITEL---SVKV----------
>tr|E4V736|E4V736_ARTGP Fatty acid synthase S-acetyltransferase OS=Arthroderma gypseum (strain ATCC MYA-4604 / CBS 118893) GN=MGYG_08825 PE=4 SV=1
--------------------PNSRLVSRCQWKPDIDFLP--------LLHH-VHRWAYTVESHLTEG---------YAVH----------------WC-T
LDQ---VPAGQ-VIISLLDLETPFFD----NI---SEED----FHTFQTCISTKGDCRIIWVTHGSQLE----CADPRYGQVLGLARTLRFELDVDFS-T
FEIDKFDANI------SLCKH--WLDPEYEFLLQDGIIHVGRFHWTPLDTYGKKKPIILSPNGSYLLVGGLGGLGRAITTWMIERGARHFIFLSRSAGES
D--SDKAFLQEVA----AQECTATIVKGSVADLDDVKQA----STVSLKPIIGIIHMAMVLRDQTFEKMTYDNWNTPLASKVQGTWNLHNVFKDAPLDFF
ILFSSVVALGGNTGQANYTTANAFLDTFVRYRK-SMNLPAWAINIGFMQGIGYASNSKLVDKANSI--QMVDESYLFDALQAAMSKSGAGSGQ------F
AIGLGTSKP-----P-SD---F-KAQPLWRFTMYQNLQTRVDK--------------PGTITAAD---LKDLIEDVKKDP-TILDTPETEEKIAKELRI-
LIGSRVGHEDRDKQEIDNMAIDSLMTIEIRSWFRRNLSLDIPLMEISNAKTVGGLTATTLNA----------
>tr|C5FXC7|C5FXC7_ARTOC Fum1p OS=Arthroderma otae (strain ATCC MYA-4605 / CBS 113480) GN=MCYG_07786 PE=4 SV=1
--------------------LNSRLVSRCQWKQDIDFVP--------LLHH-PHHWGHMVESFLSEG---------YAVH----------------WC-I
LDQ---VPANK-TVISLLDLDGPFFD----NI---SEED----FRAFQTCMSTRSNCRILWVTRGSQLE----CADPRYGLVLGLARTLRFEMDVDFS-T
IEVDRFDKNI------SLCKH--WLDPEYEFFLQNDIVHIGRFYWTPLNTYGKQT-INLSPHGSYLLVGGLGGLGRAVTTWMVEKGARHFIFLSRSAGES
D--SDKAFLHELA----AQECTATVVKGSVADFGDVKQA----ATVGLKPVVGIIHMAMALRDQAFEKMTYDSWHTTLAPKVQGTWNLHNVFKDVPLDFF
ILFSSVVALGGNTGQASYTAANAFLDTFVRYRQ-SMNLPAWAVNIGFMQGIGYASNLKLVDTANSI--EMVDESYLLDALQVAMSNSGAGSGQ------F
AIGLGTSKP-----L-SD---A-KTQPLWRFTVYENIQKQVEK--------------IGTISGAD---LKSLVEEVEKDP-SILDTQDTEEKIAKELRV-
LIGSRAGLENADKKEIDNMAIDSLMTIEIRSWFRRNLSLEIPLMEISNAKTVGGLTTTTLNA----------
>tr|G4N917|G4N917_MAGO7 Fatty acid synthase S-acetyltransferase OS=Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) GN=MGG_14831 PE=4 SV=1
--------------------ESRAGCFGQNWHEDVDLLS-----DEFVVTPASQKLAQAIVDTIKSGK------KCTSLA----------------WE-D
VT----KEQGQYCICL-AEWESPILV----DL---TDEN----WTRLRDVVL--GSAGTLWVTGGAAMD----TPEPLKSLMVGLARAIRNENA--GVLT
LDLET--AADMRQGCDAVLGE----TPDGEFAARRGRVFVPRVERLPGVTPGKPKV-PIVADATYVV-AGLGGICREIGRWLAEKGAKHLVFLSRTAASS
A--ENKEFSAGLEK---TYGAKIHAFDCDVGDKTALAGVLEA--IGHLPKVRGCVTGAMVLHDTLFDSMTADHVRTTVGPKVHGTWNLHEQLP-ADMDFF
VMLSSLAGVMGHRGQGNYGCGNIFQDYVAAHRR-GLGRRATTVDIGYLLSVGFVAHDEYVDHAMGL--KVMRSSDLHGLLATAMEAD--LDA-------S
PAQVMCGLP------------YRDDAWYWRFAALRNVGAA-------------------G-AAAGS-GGGISLREELARC-GPGDDEAAVDLITRALVQR
LAKLMMMPDIDAGRPLSAYGVDSLVAVEVRNWVSKEVVVEVSVFDLMANVPMRVLAA---NL----------
>tr|C3H370|C3H370_BACTU Uncharacterized protein OS=Bacillus thuringiensis serovar huazhongensis BGSC 4BD1 GN=bthur0011_29060 PE=4 SV=1
--------------------NIKDWFYLPSWERKTLKSIKKEQKYKWLIFNDHLNRFNRLIEKLKREGDVIEVKTGGVFSEKSDGLYTICPSQKMHYEML
FSELEQKDLLPNKIIHAWSFNPVNEVIDQERIERSMDEGYYSLLYIAQAIGKYEGALQLNIFTDRMFEVTGELNLKPEQATILGFSKICNLEFQNIKCRT
IDMDTD---SQQMFEEAGLMESFVDSTDIVVAYRGRHRWAQTIIQSPFEEEDVE-IDRLREGGVYLITGGLGGIGFEIAKDLANVPNVKLILIGRSEFPR
NQWEQYEVISDLLT-MESQGAEYMILSSDVSNQDDMKQAIEKAKSRFGS-INGVIHAAGVADYLGIMNREKESNNKILAPKIKGTLVLDALLKDEPIDFF
VLCSSIGNVAYHMKFSGYNAANEFLDAFAFYKRAHDGVFTVAINWPDWQEVGMSLKSAE------------IWAKQFNMDMESVL------HDGVT----
-----VEE----------------------GLKVFRSIINRNQQQVVVSIDLHWKLL----------NGANYYNELLEKGSSSTTYRPPTNEIEQQLYEL
LKDMFGIEEIGIYDNFFDLGMSSLDLVRINVKLKEAFKRDLPIVVLYEHTSIKSLAKYLSN-----------
>tr|A0A0F4QHA7|A0A0F4QHA7_9GAMM Uncharacterized protein OS=Pseudoalteromonas rubra GN=TW77_18075 PE=4 SV=1
--------------------DVSDYLYEPVWMAKFIDEEESRNPKSAVIFVDKHGLYKGVVEKLKSNSRVYTVSLLEGGGEDDCVDYFIEKNEFASYSKV
LGDIKKKEPGLDLIIHAFNVQA--DSDDIHNQDDYFELGAYSLLYLAQGLHESDQECVLKVLGTNTLNVGQ--SVNPFKQALTASVRVIENELPFISSQL
IDVSEV---IQQQLPNSCMQTILGEVEHQVVAIKNGVPWYRQYQKVSVTLADPS-KLPVKANNVYLITGGSGGIGLEVANFLSEHSSVEIVLVSRTPIER
ASWNSIDVVEKIKA-VESKGSRVHTYTADISDCEQFTQTYQAIVKEVGK-PNGIFHTAGVPGGRLLSLLSKQDAQKVFAPKVAGSLNILKTIDLEYVDFV
INFSSISAL--NGSIFDYATANAFQDGLSNINALC-QQKVKTINWDTWKEVGMAVKSVA------------P--KGYQTLLEQQL------KSGLE----
-----NNE----------------------GLKALSFALSCNKRHLVVSSSPHFDIP----------FD----LELIKDAGSDSNHDRTITATEQSMKNL
WKDILGVEVMSRSDDFFELGGDSLSLSKLLAHINHQWQLNLSLKQAFEKTDFHSMLRLVEG-----------
>tr|A0A0Q4QFQ0|A0A0Q4QFQ0_9BACL Uncharacterized protein OS=Paenibacillus sp. Leaf72 GN=ASF12_16675 PE=4 SV=1
--------------------AEATLHYAMQWRKCSRSPEPSGIDGAAVVFMDRAGVGQTAASLRESGRLVIEVEDDGPCTANSNEGYQID-GSKASYLQL
MQALKD--VPFGQIIHLLALDAHDVSDSLETLKRRQASGAYSLFYLTKALVQAEIQQPLALHILNAVEATGAELLIPDHAPVYGMGKVMAKELSNVSCKY
MDIEESVPL------GQIIGELQ-ANDVYGVALRNGDRYTEIFAEVQLETSR---RLELQEQGIYLITGGLGGIGLEVAKWFAAQSKVNLALISRTPLPP
SSEEASDKLRIV-KELERLGATVECISADAADYSAMEKVIADLKSKYGQ-IRGIVHGAGVSNDGPLADRGDDMFNAIYAPKVYGTWVLDALTKDQKLDFF
IMFSSVATIFSAFGQGDYAAANAYLDAYAPYRQ-RRGGRTLTVNWTTWKETGMAFDG---------GHVFDTIFRTLPTELALEGFA-SLLQSGAS--RA
LIGQIHYDGAGA----------------MLLERSGVSCSDSIRKRIAAKKDSKRKQDGNVQKKERSAEGVVMLGR-------E---AGSYSELEQKLALC
CKLVLGYEEIDIYDNFFEMGADSLVLMKLQGEIETHTFEMVTISDLFEYSTVVQLAEHLQKQ----------
>tr|S9TCG8|S9TCG8_PAEAL Amino acid adenylation protein OS=Paenibacillus alvei A6-6i-x GN=PAAL66ix_04999 PE=4 SV=1
--------------------PLQNRFYRMEWRKENNQPEAWLSTGTALVFMDNSGRGKAIEAFHSRRRKTIIVD---ECKRIDATRFTID-GTRESYCEL
MRNLED--VDISQIVHLWTLNYTGMASQVDEIRESQKLGMHSLYYLTKAIANANISNEIDWVTVYYTEVTGDERLIPENAPAYGIGKVITKEHPNVKCRY
IDIEESTTD------SVVIREVAAVSGHYIVALRNGERYTEVFTERELER-R---TAGIREEGTYLITGGLGGIGLEVAKYLAAERRINLVLLNRSGVPP
REQG-TRRIKAL-KELERMGANVECLHADVAVREDLEQAYLHIKKKYGV-INGIIHAAGISSDGPIVDRGDEMFEYIYAPKVYGTWLLDSLTDDDNLDFF
IMFSSVATIFSAFGQSEYVAANAYMDAYSAYRN-KQGKQTLTINWSTWKETGMAYES---------GHALDTIFKALSTADAIEGLD-TLLHSNVT--RA
LVGEIKYEGSGA----------------LLLERSGVPCSETIMNLIAEKKQKQQ-KPRSAKKNESGMNGVILHGR-------D---DGAYSEIERDLAEC
CKKVFGYHDFDIFDNFFEMGADSLHLMKLQSEVEAQALTSLSMGDLFEYTTIFELAKYIERR----------
>tr|J3AWZ0|J3AWZ0_9BACL Putative polyketide synthase component,beta-ketoacyl synthase family protein OS=Brevibacillus sp. CF112 GN=PMI08_04770 PE=4 SV=
--------------------DAADWSYRPTWKRAAFSD--WSAKRSAIIFHDVE-LAEAVEACKRQ--FAQPFRGGAPCAENGC--GLAD-DSQASYTDV
LQTYWQ--KTKTEAILYMALSEDEFVEDQEQAARMLDATYDSLLHLVQALDEVNGAAAIRLAVVRLFDVLGSEPLNPWKATLLGLVRGIPLEFPDRNCQL
IDISCQEQLVA---SGLLLQEIAG-GQDELFALRGKAKWLPLYEPVSLPARS---GAALKDGGVYLITGGTGGIGLELADYIASHCQASLILLGRSFFPA
KEEGKQDAIAQM-RQLEQKGAQVYVCQADVSDFPALAATLQRVQQEAGA-IHGVIHAAGLPGSGLIQQAKKETSHQVILAKAAGCLNLNRILRANDLDFF
VLCSSISTLSPMIGQSDYNAANAFLDAYAEYRN-RDGNEAINLKWDIWKNVGMAVKS---------GIAPSPSFQAGGKELFVARLSQSLLFSTGT--VG
TIGTIER-PPGS----------------VHLEALKARCADRNVQVMAGKASVAERIDGNKPSDDFGQIGIDIFGKALAAQGKRPPLSAPATDLQKALCAI
YENHLGIAPIGIADDFFELGGDSLKAIHVSTSIRKQCQANITLTDFFQEKTIEKLAAFIANS----------
>tr|A0A022PLI7|A0A022PLI7_PHOLU Amino acid adenylation enzyme/thioester reductase family protein OS=Photorhabdus luminescens BA1 GN=BA1DRAFT_00451 PE=4 SV=1
-------------------ANVAQWCRHPRWLPKPLGEA-KQNRAPWLIFGAQAAEL-SDLWQA-AAPGSIVVEDANEFLQQSTYRFSLRKDQPEDYQRL
IDCLIQQQVLPERIIWCWTAAVIEA---------A-FEQLAA---AIKALTGHHKAFNITLLS---RGLQAARVEACNAAPALGLLGILAAEYPGYSARH
IDLDDD----TFATYQSLITELYTDMQPTSITLKQGERELQTFTELDEIPR----RQILRDGGVYLITGGLGGIGQLLARHISDKCSKKLGILSRRETNT
SE----ALFDALRKS----GAEIMMLRADVADSAALNDALAQMRAKFG-AINGVIHSAGIEASGLLEHGTSQNWRHVMAAKVSGTQQLMTAISQDSDFVL
LCSSLA-SLVGGIGQADYAAANRYLDAVAHYWR-QQAIPVTSVNWDTWSEVGMAVDYAAR--RK-------ESVIGLSNQEGCAIFD-------------
---LAI----AGMEAQIVVSKFT------T--VR--------RPQL-----------------------------------QNSSAISDSASPEEAVRQL
WYELLGEETIHLEDDFFELGGHSLLATQMISRLRDHFQHCLTLAEFLEQPTMARVVRSLSDDKK--------
>tr|A0A0Q0D9U0|A0A0Q0D9U0_PSEAP Amino acid adenylation OS=Pseudomonas syringae pv. aptata GN=ALO85_04588 PE=4 SV=1
-------------------TEPLDWCQAPAWRPALPPRSDSPLQGPWLVVMRGVAAD-NSMLFSL-PPDSVCIADAGD---SGTAVAIIARGDAQAYEQL
FNTLAAQEALPSQIIYMAGGAQPEHAA-----ITL-FTDLMS---LVQAYIPHAANTVLSLVT---EGACQVDPNSC-VATLSGVVRTLTWELPQIQCRH
FDLPLA----NAAENETLLLQALQHIDPSTLALRKQTFHEPCLRALQVLQP----PQQFEEGGTYVVTGGLGGMGLALASHLAAKVKATLVLMSRSATVD
VG----QALQALEQQ----GARIQHMAVDCADREVFTAALHQVRRQHG-RISGAIHAAGVQASGLIQLSQANAWAQVMGSKVVGTDVLIEVLREEPEFIF
LCSSLA-SVLGGLGQADYAAANAYLDARAQACR-QEGMPVVSLNWDAWAQAGMRVAYDRA--HP--EQAPIDEVRGLTNAEGCQLFE-------------
---LAL----AQNTAQIVVSKAQ------DLQQL--------INQLQRGGTTSA-------------------GRATALFDSGAERVAPRNAVEQEVAQL
WQELLGGDMPGVLDNFFDLGGHSLLGSQLISRIRSRFQQCLTLAEFLDEPTIERIARSLGSGAD--------
>tr|A0A0N7J2E2|A0A0N7J2E2_9BURK Thiotemplate mechanism natural product synthetase OS=Burkholderia plantarii GN=bpln_2g02060 PE=4 SV=1
-------------------RDLADWCRVPRWRDEAASAGRARLDAPWLVFADDTAV--AGRLAAHAPAGSLTIVPGERFAHADAACITLRANAADDYRRL
LEWLGQASIAPSQIVYGWSAADPLD---------A-FERLAL---LVQALGARHLATTLTLVT---RGWRTAQADDG-AATMAGLLQAVNWEFPKLLVRH
LDRDDD----SDATLTALADELAHATVPSTLAFAAGRRQTLRYVPIESEGE----SLAVRDGGTYLITGGLDGIGYEIAHHLATAGRGKLGLVSRSGLDR
RR----QRVAALEQA----GAEVLVLQADIGDAQQSAQAFSAVRARFG-EINGIAHSAGLEASGLLGSGTPQAWRRVLGPKVDGTRHLVAQLGETRDFVL
LCSSLA-SVLGGLGQADYSAANASLDASARHLR-RRGIRAVSVNWDAWAETGMALAYAAR--AAKAGKGAAAPIRGLSNQEGRALFA-------------
---LAA----AGGEAQVTVSKYG------SIERL--------IERELAQRHA-----------------------DSGARAGESRQDGGAETVEAFVSRL
WRDMLGVDALTADDDFFELGGHSLLATQLISRIRERYDHCLTLAEFLDMPTIARIAASIEAAQD--------
>tr|A0A0F6G6M6|A0A0F6G6M6_BURPE Amino acid adenylation domain protein OS=Burkholderia pseudomallei MSHR2543 GN=BG16_5266 PE=4 SV=1
-------------------RDVAQWCRTVSWRDAPAARA-L-PPERWLVFGDE--------WFALAPAGSVLVREDDAFRAHGDNGYGVRPGEKADCDRL
LARLAEQGGVPAHVVYGWAQTDVDR---------A-FAGLAA---LLQALGAHPADFRVSLVT---KGARSARTDACAAAAPAGLLKAVRWEYPRIVCRH
IDIDDA----SDATIDALRAELSSEPATSSIALAGARREAPGFAALPAVAR----DDVLRDGGAYLITGGASGIGLELAAHIASRRRDRLALLSRSPHDE
NA----ARFAALDEA----AASVLRLTADVAHAAQLADALRTVRARFG-RIDGVIHAAGVEASGLLETGTPDAWRRVMAAKVHGARHLFDQLAGDPDFIV
LCSSLA-AVVGGLGQADYAAANGYMDALAQYWR-QRGVAAIAIDWDTWSDTGMAFDHAAR--TRRSND-RPGALPGLANREGRALFD-------------
---LAL----AHDAPRIVISKRG------FEQDR--------RDAP-----------------------------------TRARRAAAPGDAQAALVAL
WQELLGVEQVGVDDDFFDLGGHSLLATQLISRVRDQYARSPTLGEFLEEPTIARLLRAIDHTGG--------
>tr|F1TIW2|F1TIW2_9FIRM Beta-ketoacyl synthase (Fragment) OS=[Clostridium] papyrosolvens DSM 2782 GN=Cpap_0012 PE=4 SV=1
----------------------------AEWKGKPVHTNKTEMPENIILFMDFNREHEIFAEQIKASINIVQVYPGSRYEKISDIKYVVNVEDKDSFVLL
FNELKDRNIDLANIVHLWNYSKERSGIHLEQFDRSQYLSSYSLYFIVQVLSKLRTRSTIRIISSNSVVFEEDYI--EQKSTVHAVANVINQENIGVKCFS
IDSD--EN-IG--IYEVLLNELS-DPSQELVTYRRNSRWVRDIVKLN--KGKFD-NIYFKSQGTYVITGGLGGVGSEIAKFIAKNYKSNIALIGRSNKET
AI------IDEL----KEYGAKAAYYKADVADEVSMSQCIGRIEEDFG-GITGVIHAAGIVKDCISVNSSIEDVKEVFAPKVKGTLILDKLLRKENLDFM
ILFSGMVSFYPNQGQSAYAGANMFMDSFAFKRQMEQKARTIAINWWFWGETGMAAKPDIIESLKSRNLSPITNKQGIDAFKRILSTGAVQVLMNND-SQA
PIEVAVQHSK--P----------------TAD----SVAKGIVVKKGSNQIGLLK-----------TLTKKYLISKIDKLIGIVIDETDT----------
------------NTAFLDLSIDSITLINLSSELEKDAGIMLYPTVFFEYNNVEKLSSYLLEE----------
>tr|F1TBP3|F1TBP3_9FIRM 6-deoxyerythronolide-B synthase OS=[Clostridium] papyrosolvens DSM 2782 GN=Cpap_2600 PE=4 SV=1
----------------------------PYWTEIEKEQIKPLTLKTLLVFEDIKGKDSPLVKFYENGCKVIKVSKEFSYKKINEDQYNINPYNKEDYQNL
FSSLHKDGIAAEGIIYAFDLNRQEVADHFAAVEDGKVLGLIALINSMRVYN--LDETHIAVVTSNAFIVDKGYN--YQAAVA-GLIRTIPHEYGNIKGVL
IDIE--EN-SLERTLKLIADYLMNQYKKEIVSIRNGRLFAQTFKKFC--INQDM-NLPLQDQGVYVIAGGLGGIGLEIAKAIAAKVKARLILIGRSPFPE
RS------IQDI----EAKGSQVITLAVDVCNEKQLTSALESIRTKFD-HINGVINAAGILEDALINRVTKEVYEKVTKAKILGSCLLDYATNKDNLDFF
VIFSAMVTYFGNAGQAAYSCANAFEDSFAAYRNFVKGKKTIVINWGVWEEVGLVADSVSKKSLEERGIIPLSTSEAIEGFYSCLTEKHFQFGIGKL-SKD
-LENLIS--R--L----------------ITT----KLSRSISNSLSGHFTMDIE-----------KLLKEYLLKKINELRENSSKPMNY----------
------------KTSFLDAGLDSITIVNFTENFENETGIKLYPTVLFEYPTIQELSKYLLKN----------
>tr|A0A0L6JKS6|A0A0L6JKS6_9FIRM 6-deoxyerythronolide-B synthase, Aspartate racemase OS=Pseudobacteroides cellulosolvens ATCC 35603 = DSM 2933 GN=Bccel_1693 PE=
------------------------------------------------ILEDVNGIGKEAVRLRNDGMTVIEVECGNEYKKSSTINYTIS-GDEEDFKKL
FADLRGEKIA--RIVHMFSITSAT-VDSVKKLDEKLDNGVLSLFHMYRSLESGVKDLDVVLLSQYVNEVDEKCI-NPENAAMFGLGKVINMENPEIRCRA
IDVDGE------TNIEQMILEIYAGYKEYNVAYRRGKRYIQELDCIDAEEY-REKEIKLKHDGVYIITGGLGGLGLETAKFLASKGKITIALLSRTKMPE
REEKNGTDKKKDILYIEKTGARLVCCSVDVSKEEELRETVARLKSRFG-RINGVVHSAGIGAGGSIRNDTEEIFKEVLKPKIQGTWLLKQVTGDDAPDFF
AVFSSPITLMGGAGSGSYTSANAYLDSFTAYNN-KLGNRTIAMSWAPWEETVKAAGLVMDK--SRHMFDILSTTEITGSFWEVLNKNSPMVIVGRINYKS
ILYLAFRI--------------S-QRIRSQMERLSA------------RNET----------SRENLSILKTAD-----VKLTGREHGWYSTSEKQLANV
LGQVLGYNELNINHNFYELGGDSIIAARAVGILNKQMGLNIKIADLLKNPNLREFAQYIELK----------
>tr|W4DAU6|W4DAU6_9BACL Putative polyketide synthase component OS=Paenibacillus sp. FSL R7-277 GN=C173_20446 PE=4 SV=1
------------------------------------------------VLGGGGERERALASLQADTENVIPVTIT-DYCAKEGERFFIT-GDRTGYQWL
FRQIGISGKV--QLVHMTSVGSVNAADDYMELGTSMIDPVINLLTLIRTFQMQIQEAELVIVTRYAYLV-TDLV-QPVNAALHGFAKSFHWEFPQVGCKC
IDIDDA------TELSVITREVLCQSPYFITALRAGRRYYEELNPMSETTVHELRNVGIKENGLYLITGGFGGIGLELAKYLSGKKKVRLILLGRSRLPD
TDA-------DMIKQMENSGSTIIHYAADIADFDRMKQIMEEIRVIHG-PLNGIVHCAGNGMVI--HELSEDSLRGILRPKVQGTWILDRLTCNEPPDFI
CLFSSAMTLIGGYGAAGYTAANSYMNSYASMRC-SASTPFINIRWPEWTDTGLAECKQTNL--RKELFEPLLLERAIRYFDWVLHHNVHDLIPGRINWGC
ELQLPIRF--------------S-ESVNEEFHKRQQ------------LRP--------------------DAD-----SRIQVNNKTATRTIEQKIGSL
IGELLSYEHVDYNQNFFELGVDSIIAAKIINRIQNQLNCSLEVADIFRYPTVHQLSGHLETL----------
>tr|B8I5I0|B8I5I0_CLOCE Condensation domain protein OS=Clostridium cellulolyticum (strain ATCC 35319 / DSM 5812 / JCM 6584 / H10) GN=Ccel_2383 PE=4 SV=
------------------------------------------------FFSDKSRSCNEINRLEAKGIKVIEVNTGEEYGVLGKDKYSVG-YSQEDFYQL
FSQESIKDIN--YIVYSPD-SGLPDTSDIKILENKLENSVYNLFRLTKAWQKTGKDIKIVILSTYVNSVTEECL-NPENAALFGMAFVLKKEYPNLKIKC
IDMDEG------CEAESIISEFQTVHKTRMIAFRNGRRYIEQLKRVKREQN-PSNSVKIRENGVYIITGGLGGIGLEIAKHMASGTNLNVIMINRSEMPE
RSQETEKDLKKSIMDIESLGSKVTYYNGDVSDMQSMKLIIEDVIKNYG-KINGIIHSAGIAGNGAITK-DEKRIKEVMAAKVKGTWIIDSLTSNLNMDFL
LLFSSAETLTTSAGQSDYTAANYYMDTYCYYRN-KRNQPTFCINWAAWKETGMAKEHNADR---DGVFMVLSTANGVRVFDEVLKSGQPRVIAGQLNYNL
LASLPVTL--------------E-PELSAVLDRSKK------------TRKSD---------IIAGTTKQDTVD-----IKLTGKTDDQITKTEQAIGYI
WASIFQSNEINVYDSFYDQGGDSIFAMKITNVIRNTWGINISITDVMNNQSIYELGKYIDSE----------
>tr|S0FJD0|S0FJD0_9FIRM Beta-ketoacyl synthase (Fragment) OS=[Clostridium] termitidis CT1112 GN=CTER_5158 PE=4 SV=1
------------------------------------------------VFKNTNTLSNKLEMFKQHEKPVIEVSIGNKYNKVNDTKYEIE-NRENDYKRV
IEEVKREGIS--QIIHLLTLTDNEPIYSAEMLEEILNKSTHSLRYIVKGLHQSLKGVNIALISQYVETVDEKVI-RCENAALFGLGKVINVENYDIKCKF
IDIDDS------TDVTNIKRELSFENCESNIAYRNNKRFVKALDVLDIQKL-DNVNTEVRDEGVYIITGGIGNVGLEAAKFIASGHEVKIALINRSKMPE
RGQHQGTDIIRLINDIESNGSVVEFFSADVSKEEEIIPLIDSFRCKFS-KINGVIHCAGIGVGGRVEDDSDEIFNKVLAPKVQGTWLLDKATENDKLDFF
IAFSSPITLTGALGSGSYTSANAYLDSFVMYRN-RLGKRTINIGINKFK----VKSNIIDD--DKRLFRPINEDDIANAFMLVFSKNIQSVIVGLLNYDN
EIYLPFII--------------D-NNLKQNMKLHRE------------KQVVQ---------LKTTVTNAKSTH-----YRLKGNNEQGYTETENLLGSV
FCSVLGLDEIDIYDNFYELGGDSIIAAKIVNIINKEKQLDIKITDLLRNPSIKLFAKTLDIN----------
>tr|A0A0A6PNY8|A0A0A6PNY8_9GAMM Uncharacterized protein (Fragment) OS=Candidatus Thiomargarita nelsonii GN=OT06_07260 PE=4 SV=1
--------------------TIKECFYQLTWQPKPGVSKEHQSTGTWLIFADTGGVGKALAQLLQKRGASILVYAG-----------EINPANPTDFENF
FQK--RLDTNLQGIVHLWSLDAPLPDELTVTALEQ-SLGCASVLHLVQTLEHY-NSTSLWLVTQNAVPVKSGHLTALAQSPLWGLGKVLALEHPDKWGGM
IDLAPVGD-----NAATLLTEILAPDTEDMIAYRDGQRYVARLVPNCLTDSS---AISLATKASYLITGGLGALGLRVAQWLIAQGARHLILTSRRQP--
-SKQAQETI----NQLRQDGVNVLVANADVANQSEISMLFETIGNTM-PPLRGIVHAAGVVGYEPIKDIALDSLQAVLRPKVQGAWILHQLTQKMSLDFF
VCFSSIASVWGSKGQAHYAAGNHFLDMLAHYRH-GLGLPALTINWGPWADDGMASSEQAQTWLNRQGVETLPPQSAIEALSYLLGTKE--CQCTVNWSLF
KEIYTLREQ------RPLLEHIKVSQPQTVVEIPPVDILQQLKNAQKSDG---YEL-------------------LTTYLQEEVTKIVG---------LE
FSE-----WPALQQGFFEMGIDSLMAIELKNRLVASLGASLPATLIFDYPNIQDLAKYIGHK----------
>tr|A0A0J6WI14|A0A0J6WI14_9MYCO Phthiocerol/phenolphthiocerol synthesis polyketide synthase type I PpsB OS=Mycobacterium chlorophenolicum GN=ppsB_4 PE=4 SV=1
--------------------VPAEWFCALTWPVKPLAE--APSHGAWLVVGDA-RIGEAMARLLGGPVTL-----------------------AAGDDGL
ADAVA-----ATHVLY--APQERDGDELGYELFEAGAI--------A--SAASPARPALYLVTRNAQPVSEGDRANPAQAVLWGLGRTLALEHPEIWGGL
VDVDASVPA---PVTARW---VLAGDGEDQVVYRAGTRRVARLVHQPPTAAG---TAVLDPNRAHLVIGATGNIGPRLIEQLAAMGAKTVVAVSRNPG--
--GRLDELT----ARLATTGTTVVTAAADASDETALRALFDRFGTDL-PPLGGIYLAAMSGGPVTLAEMTHDDVVAMFRSKMDAAALLHTLSLGHPVEQF
VLFSSISGVLGSRWLAHYAATTTFLDTFAFARR-AAGLPATAINWGLWKSLADVQEGFEKQATAESGLEPMDDDTAIEALRLFVGPVAP-ARATADWPRL
AAAYHTRAQ------LHILDDLLAEDAG--TQAALTPFRGELRAADPERR---RDL-------------------LADHVGAQVAAAMG---------LA
SAH-----TLDPTVGFFQFGMDSLMSVTLQRSLSESLGEVLPASVVFDYPTIEALTDYLASV----------
>tr|A0A0J6VRH7|A0A0J6VRH7_9MYCO Phthiocerol/phenolphthiocerol synthesis polyketide synthase type I PpsB OS=Mycobacterium obuense GN=ppsB_2 PE=4 SV=1
--------------------VPAEWFCDLTWPVKPLVA---AEQARWLVVGDV-RVGEAMAHLLGSPVTR-----------------------AAADDGL
AEAMA-----ATHVLY--APDAGDAGDLGYGLFETGAI--------A--AAASPTPPAVYLLTRNAQPVNEGDRADPAQAVLWGLGRTLALEHPDIWGGL
IDVDASVPA---PVAARW---LLAGDGEDQVVYRAGARRVARLVHQLPTAPA---SAGLNPDVAHLVIGATGNIGPRLIEELARMGAKTVVAVSRNPG--
--GRLDALT----ARLAAAGTTVVTAAADAADEAALSALFDRFGTDL-PPLGGIYLAAMSGGPVTLAEMTHDDVVAMFRSKIDAVALLDTLSLDHPIEQF
VLFSSISGILGSRWLAHYAATTTFLDTFAFARR-AAGLPACAINWGLWKSLADVQTGFEKQATAESGLEPMADDVAISALRLFTGPGAP-ARTTADWPRL
AAAYHTRAQ------LHILDDLLADDAT---TTALTAFRTALRDTPPEQR---KDL-------------------LGDHVGAQVAAAMG---------LA
SAH-----TLDPTVGFFQFGMDSLMSVTLQRSLSESLGEVLPASVVFDYPTIEALTDYLASV----------
>tr|X8FDM2|X8FDM2_MYCUL Short chain dehydrogenase family protein OS=Mycobacterium ulcerans str. Harvey GN=I551_3205 PE=4 SV=1
--------------------AVDSCHYRVGWPTKPLADTETASGTRWLVFADA-ELGAELGLAAGAQTVD--------------------PSALTEESEL
LAALG-----VEHVVY--APPAGKSLDAAYQLFHQVRL--------V--AVKASLTAKLLLVTRNAQPIAEGDRANPAHGVLWGLGRTIALEHPEIWRGI
IDLDESMPA---ELAAPK---ILGTDGEDQVVYRCGGRHVPRLQRRTAPAVA---PVTLDPNSSQLVIGATGNIGPYLIRQLAQMGAKTVVAVSRNPG--
--QPLQELA----ESLAAEGTNLVIEAADATDEAAMTALFDRFGADL-PPLDGIYLAAFAGGPVLLNEMTDADVRAMFAPKLDAAALLHRLSLKVPARHF
VLFSSISGLIGSRWLAHYTATSGYLDALAYARH-ALGLPATTVNWGLWKSLADAEHDA-SQVSVGSGLLPMQDEVAIGTLPLLMNPAAG-VHSVADWPLL
AAAYRTRWS------LHIVDDLLRDFAE--ASTIPASHLS-----AQEVR---TEF-------------------E-AGLRRIVAREL----------RV
SES-----DLETDRPLAELGLNSLMAMAIRREAEMFVGIELSATMLFNHPTVASLASYLANR----------
>tr|A0A0A6P3X6|A0A0A6P3X6_9GAMM Uncharacterized protein (Fragment) OS=Candidatus Thiomargarita nelsonii GN=OT06_50335 PE=4 SV=1
--------------------TIKDWLYQIEWQSQPRSSAEIQSADRWLIFADQGGVGQALAEFLETRGYCVLVYAG-----------KVPPMRLADFKRL
FNE--EK-ISISHIIHLWSLDAALSEELSLSALEQAQLNCGSVLHLVQTLCNKSVLPRLWLVTRGAVPIGQ-HPLSLAQSPLWGLGKVVALEHPEFWGGM
LDLSPDATF---DETGMLLAVIQDSQGEDHIAFRNGQRYVARLVAKPPELRS---SVGFDAHYTYLITGGLGALGLKVAQWMVAQGVRYLVLTGRHGAS-
-TNQAQETL----KQLEQAGAQVRVAKADVANQEDMSRVFAEMEAEM-PPLRGIIHAAGLLDDGVLHQQNWERFKRVMAPKVAGSWHLHTLTQEQQLDFF
VCFSSIASLLGSPGQGNYAMANAFMDALTYYRQ-AQGLPSLSINWGPWAGTGMAANLDHGR-FADRGIKTLQPDMAIAALEYLLGTDC--VQSSVDWNLF
KAFYEATER------WSLLEQLTEVPTERGTESV-PTILQDLENASAKER---WEW-------------------LISYLQGEVAKILG---------FP
PSQ-----LPDIQQDFALMGIDSLMAIDLRNRLQTKLGRSMPST----------------------------
>tr|A0A061A1W0|A0A061A1W0_9ACTN Beta-ketoacyl synthase OS=Streptomyces iranensis GN=SIRAN6340 PE=4 SV=1
----------------SVRSAVDGWRYRVTWKPVSERLGTGVLGGCWLVVVPAEAWAAGVVRMLAGRGDVRVV---ESA--------------AVDRAGL
ADELRTAGGSVAGVFSLLAVESA--------------SGLLRTAALVQALGEVGVGARLWVATRGAVSVGRSGVVSPAQALVWGFGRVAALELPERWGGL
VDLSES--VDERA-LGRLAGVLAPGSGEDQVAVRASGVFGRRLVRVVGSRTS--GDEGWRASGSVLVTGGTGALGAHVARWLVANGAEHVVLTSRRGLEA
PGA--AELRDELAA----SGARVTVAACDVADRDALAELLASI--PAEFPLTAVVHAAGVLDDGVLDALTPERFASVLRAKADAALHLDELTRGLNLSAF
VLFSSITGSVGAAGQGNYAAANAYLDALAELRR-AQGLPATSIAWGPWADSGMAGDDAMERRMRREGMPPMAPESAVAALRQALDLDDAVTVADIEWENF
TRTLTAVR----------------------PSPLIAELAAVAG-------PGAATGADTVKVVTD-ADSASPLGERLSG--------LPRAEQDRALLLV
RASVLGHGAVAAGRAFKELGFDSLAAVELRNRLNAATGLRLAATLSYDYPNATALADHLRTE----------
>tr|A0A056EQB8|A0A056EQB8_MYCTX Phenolpthiocerol synthesis type-I polyketide synthase PpsB OS=Mycobacterium tuberculosis BTB05-013 GN=X094_03036 PE=4 SV=1
----------------SESRALEDWCHQLAWPIRPAVSADPPSTAAWLVVADNELCHEL-ARAADSRVS----------LSPPAL---AAGSDPA---AL
LDALR--NPPVPGEL--LDI---ESAYQV--FHATRRLAAA------MVASSATAISKLFIMTRNAQPISEGDRANPGHAVLWGLGRSLALEHPEIWGGI
IDLDDS--M--LA-VRHVLTAAH-TDGEDQVVYRSGARHVPRLQRRTLP---G-KPVTLNADASQLVIGATGNIGPHLIRQLARMGAKTIVAMARKPGAL
D-----ELTQCLAA----TGTDLIAVAADATDPAAMQTLFDRFG-TELPPLEGIYLAAFAGRPALLSEMTDDDVTTMFRPKLDALALLHRRSLKSPVRHF
VLFSSVSGLLGSRWLAHYTATSAFLDSFAGARR-TMGLPATVVDWGLWKSLADVQK---TQISAESGLQPMADEVAIGALPLVMNPAAATVVVAADWPLL
AAAYRTRG----------------------ALRIVDDLLPAP--------------------EDV-GKGESEFRTSLRS--------CPAEKRRDMLFHV
GATVMGMPPLDPSAGFFQLGMDSLMSVTLQRALSESLGEFLPASVVFDYPTVYSLTDYLATV----------
>tr|A0A066Y530|A0A066Y530_9ACTN Uncharacterized protein OS=Streptomyces olindensis GN=DF19_21895 PE=4 SV=1
----------------RVDAALTGRRYEVVWRPVTERPV-PGPAGHWLLVTPGADWAEAALGALAARGRVTVLERTGAG--------------PEDRAGI
AERVAEAGGPVDGVLSLLALDERPHPAH-----GALPSGVAALLGLVQALADLGTRVPLWSLTCGAVSAFDGPLLHPVQAQVWGLGRVVALEQPQVWGGL
IDLPRE--PGAEE-WRRLCAVLAGG-EEDQLAIRPGGARVRRLVPAPVP--A--GGPVWRPGGTVVVTGGSGALAPHLARWLADGGAEHVVLVSRRGPDA
PGH--AALSAELAG----RGTGVTALSCDITDRESVRALLREAA-RLGGPVRAVVHAATATRLAPLTATGAAELADVLGAKALGAVHLAELADPDDPPEL
VFFSSIAAVWGSGEHGAYAAANAFLDAYAEQLR-QRGRAATAVAFGAWRSDELP-AELDEEQLERQGLPLLEPRLALAGLGRELA-GGPVALVDVRWETF
APVFASAR----------------------PRPLLDEIPAVRG-------ALRGAPPDAGGT-----SADGERLRRLAR--------LPEAARAREVLVV
TSAVLGHSRPAPGRTFKELGFDSLTAVALRNRLRAATGLPLPVTLVFDHPSPQALARFLTGR----------
>tr|Q1MX75|Q1MX75_9ACTN Type I polyketide synthase OS=Streptomyces sp. NRRL 11266 GN=tmnAII PE=4 SV=1
----------------RTDAALNSRRYEIGWRPSAERRT-PGPGGHWLLVTRDGAWAGAADTALRARGRVTVVALDERA--------------ADDRADV
TRRVSAAGEAVDGVLSLLALDERAHPGH-----PALPSGVAGLLGLVQALVELDVAAPVWSLTCAAVSALDDVPAYPLQAQTWGLGRVVALEQPQLWGGL
VDLPER--PGDED-WQRLCAVLAGG-DEDQVAVRPGGLRVRRLLPAPAP--A--GGPAWQPSGTVVVTGGSGSLAPHLARWLADGGAEHIVLASRRGPDA
PGH--AALAEELGG----RGVRVTALSCDLTDRDSVRSLLERSA-EPGRPVRAVVHAATATHLEPLAGASAAGVADVLAAKALGAVHLAELLAG-EDAEL
VFFSSIAAVWGSGEHGAYAAANAFLDAYAEQLR-GQGRKVTSVAFGAWRSEQLP-EELDEAQLTRQGLPLLDPEVALTGLGRELA-GGPVTLVDVDWETF
APVFASAR----------------------PRPLLDEVPAARG-------ALRSAADG-AGT-AA-AGGAGELLKRLAQ--------LPEAARGREVLVV
TAAVLGHGRPAPGQTFKELGLDSLTAVALRNRLRAATGLPLPVTLVFDHPSPQALARFLTGQ----------
>tr|A0A0F7N228|A0A0F7N228_9ACTN Uncharacterized protein OS=Streptomyces sp. CNQ-509 GN=AA958_00665 PE=4 SV=1
----------------RTDAALAGQRYEIGWRPAAERRT-PGPDGHWLLVTRTGDWADAAGAALSARGGVTVVELDERA--------------DDERAGI
ARRLSAAGEAVDGVLSLLPLDERPHPGH-----AALPSGVGGLLGLVQALAGLGVAAPVWSLTCAAVKALDDVLAHPEQAETWGLGRVVALEQPQLWGGL
VDLPER--PGDED-WLRLCAVLAGG-DEDQVAIRPGGPRVRRLLPAPAP--A--DSPVWQPGGTVVVTGGSGSLAPHLARWLADGGAEHIVLASRRGPDA
PGH--EALAAELAG----RGVGVTALSCDLTDRDSVRALLRRAA-ELGGPVRAVVHAATSTRLEPLADATAAGVAEVLAAKALGAVHLAESMDPDGPAEL
VFFSSIAAVWGSGEHGAYAAANAFLDAYAQQLR-GRGRKVTSVAFGAWRSEVLP-EGLDEAQLERQGLPLLDPELALAGLGREVAGGGPVTLVDVDWETF
APVFASAR----------------------PRPLLDEIPAVRG-------ALRSAEAGGTGA-AD-GGDTGERLRKLAG--------LPEAARGREVLVV
TAAVLGHSRPAPMRTFKELGFDSLTAVALRNRLRAATGLSLPVTLVFDHPSPQALARFLTGQ----------
>tr|A0A014MKN4|A0A014MKN4_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. PRh5 GN=Z951_43200 PE=4 SV=1
----------------RERSTVDGWRYQIAWTPVSEL-SERALTGTWMVMVPQAELVTSAATMLERQGDVARIVLDGAA--------------DIDRAAV
AERLRTADGAVGGVLSLLALDEDPCAEH-----TVVPRGLALNLVALQALVDAGVEAPLWVATRGAVSVTGSTLRSAAQAQMWGLGRVAGLEHPRLWGGL
VDLPET--FDERA-AARLSGVLGGGEFEDQVAVRTSGVFTRRLVRATAPRS---TARPWTARGSVLVTGGTGGVGGQVARWLASAGAEHLVLTSRRGPEA
DGA--AELRDELTA----LGAEVTIAACDAADREALAAVLAAI--PERYPLSAVVHAAGVLDDGVLDAMSVERVAGVLRPKVDGARNLHELTEGLDLSAF
VLFSSLAGAIGGAGQGSYAAANAYLDALAQQRR-AQGLAATSVAWGPWAEGGMAVDGALEDRLRRGGMAAMTPELAVKALQQALDLQEHLAIADLDWERF
VPAYTAVR----------------------ASRLLDEVPEARR-------ILAALGGGTAAV--F-ETGGSELRERLAG--------MSEAEQERALLLV
TAMVLGFPSVESQRAFRELGFDSLTAVELRNRLDAATGLRLPATIVFDHPTPVALARRLRTD----------
>tr|Q8RJY2|Q8RJY2_STIAU StiE protein OS=Stigmatella aurantiaca GN=stiE PE=4 SV=1
----------------SDGDETKEWLYESQWRRETPPLTASVGPGRWLILGDRGGVGETLMRRLEERGKCTFALAGNSFQRVSERRYEIRPGQTEDFQRL
VQEVFR-SLPCKGVVHLWSLDGVSTQELTLAIHAAQPLGVESALSVVQSIAWAGLRDRLWLVTAGAHVAGGEGPVAVAVAPLWGLGGTIVQEHPELRCSR
VDLSGA--RRKEE-IDALIETLW-DGSEDQIALRGGERFVARLAHWTGERARRDGEVAIRSDGTYLITGGYGGLGLTFARWLVDRGARHIILAGRNGAPE
SA---RGAIEELRK----AGAEIIAAKMDVADAEQTARVLEEAR-KTLPPLRGVIHSAVVLDDGVLLKQNRQRLERAMAPKVDGTWNLHRLTLDCPLDFF
LLFSSLASMLGAPGQGNYTAAGAFQDAFVFYRR-ALGLPAMTINWSPWSDVGQAVVANRGERLAQGGLQSINPEQGVRVLERLLQH-AQIGVMRLDLRQW
RQFYPKNA----------------------SSPLFAELMRALN-------TA---------PTKV-ASDSSVRVALQSL--------EPGPRRREMLEHL
QAQVLRMSDLDRSTPLRSLGFDSLVAVEFRNRIEASLGLTLSATLAWNHPTIEAMTTHIADK----------
>tr|A0A089VFG6|A0A089VFG6_CHOCO Polyketide synthase OS=Chondromyces crocatus GN=croB PE=4 SV=1
----------------SASGAIDQWFYEIQWWPSPLPAKTAAQGKRWLVFADQQGVGEALRAEIESRGTCVVAFLGEQLRQVSPGRYEVSPDRAAL----
-AALLA-RVDLTGVVHLWNLDLVPPAKTSLTLHDAERLGCGSLMALVQAIAGAGMRDRLWIVTAGAHAVGTRG-VAIAQAPAWGLGATIAHEHPELRCTR
IDLDGG--AGPAD-ASTLLAALG-VDGEDQIALRSAVRYVARLARTAS-AAQQDLPTALRDDGTYLITGGLSGIGLTVAEWMVQRGARHLALVGRSGASP
AA---ESALAPLRA----AGAEITTFQADVSQPEAMARVFSQID-ASMPPLRGVIHSAVALDDGVLLQLDPARLRSVMAAKMDGAFNLHLLTQERPLDFF
ILFSSLASILGSPGQGNYTAANAFVDALAHHRK-SLGLPALSLNWAPWSEVGLAVVTKRGERLAYRGLKSITPEQGKDVMERVLAS-SQVGVMLLDLRQW
RQFYPRSA----------------------SSPLLSEIAREQG-------NG----------APV-EPEAPLRSVLIAE--------ESVERRRTLLEHV
QGHVLRLSQIDPQTPLKSFGFDSLMAVELRNRLEASLGLTLSATVVWSYPTVAALVAHLASK----------
>tr|Q6DNE5|Q6DNE5_9CYAN CurH OS=Lyngbya majuscula GN=curH PE=1 SV=1
----------------SLQPDVSNWLYQLQWQPSEVKETPLATSRMWLLFVPEGVWAEQLTSSLAQLDQYVVVSPGDDFRYLSEYHYQVCPTQKESFQQL
LQKIVEKGVTLQGVVHLWSLL--SDSQQL---NQAQELVCGSTLHLIQALGEVFDSQPLWLVTQGAQCIAA-TTIHVQQSPLWGLGRVIALEHPEFKCHR
VDLDPD--NASEG-VEMLLQELL-PDAEDQVAYRQGERHVARLERFVPQSSGEEQKKEIQAQGSYLVTGGLGALGLEVSKWLVDKGARHLVLMGRRSPSA
EA---QIKIAQLED----MGVKVSVQLADVSCSQQVSQMMERIE-RELPSLRGVIHAAGVLDDGVLQNMSWQQFVKVMLPKVQGTWHLHQLTKDLPLDFF
VCFSSMSSLLGNLGQGNYAAANEFMDAVAHYRR-SMGLPGLSINWGAWASSGMAASGQHQQRLETIGIRAIEPQQGMQALGSLLSQ-PQVGVLPINWSKF
VSTLPGGQ----------------------KMPFLEALISTEP---------------------S-LTQKSAFREQLEA--------AAVSERQELLTHI
RAKALGWRKIGMRQPLFDLGLDSLMAVELKNRLESSLETNLSSTLLFDYPTVEALVEYLAND----------
>tr|F4Y424|F4Y424_9CYAN CurL OS=Moorea producens 3L GN=LYNGBM3L_74440 PE=1 SV=1
----------------YSEVAVKQWVYELKWETKKHQQLSPNKPGNWLIFADQQT--QALKTVLAKQNNCLIVTPGSSYKQLDDQHYQLNPTNAQEFQQL
IKELFTTQDTLEGVVHLWNIN--TSTEEL---EAAQELGCASVLYLVQALVSNSQSSPLWLVTQGTQNVEENPKLAVQQAPVWGLSRVIALEHPELKCRR
VDLDQT--RNSEA-LEALGKELL-PDDEDQIAIRGGVRYSARLARRTQ----KEQQIAFGTEGSYLLTGGLGALGLEVAQWMVKQGARHIVLNGRRTPSE
TA---QETIQQLEQ----TGAKISVILGDVSKEEDVASILKQIE-ASQAPLRGVIHAAGFLDDGVLQQMSWERFRKVMAPKLQGAWYLHQLTQKLPLDFF
VCFSSIASLLGSPGQGNYAAANAFMDTLADYRR-SMGLPGLSINWGAWAQGGMASRSQHQSRLRTTGMNLITPEKGLQVLGELLSQ-VQVGVFPINWSQF
LGQLPVGH----------------------TISFLEAFASRKL-------QK------------E-TTKDENFLEQLAL--------AIESERNQILIYL
QGKLLGFDLPNPELGFFDMGMDSLLTVELRNLLSSNLGCSISAAELFGTSNIQNLAEHLIKE----------
>tr|E3FQI4|E3FQI4_STIAD Tylactone synthase modules 4 & 5 OS=Stigmatella aurantiaca (strain DW4/3-1) GN=STAUR_1685 PE=4 SV=1
----------------ILEGDPAEFLYSFLWSQKALGAGAGSSPGRWLVFADHGGVGLAVARALKEAQVCTLVHPSPGIATLRHEDYHLDPSRPEHFTAL
MEAVCPQKHLPPGILYFWGLDLLGTAAEPSAWEQTQALGCGPLLRLLQALGPFREMA-VQLVTRGVFVPGERAPVHIEQSALLGLFNTFRIERPAFRCLH
MDLEPG--PRRLE-VRQLLQEVL-HEGEEQVAFRKGLRFVSRWERMKDLPASSDEPPIIRAQGTYLLTGGLGALGLEVAQWLVNQGARSLVLLGRRGPSA
EA---LPLLERLRA----AGASVEVLQADVTELGSLTQVMAHLRTPGRPPLVGVLHAAGLLDDGTLQELTEERFLKVMEPKVKGTWNLHLLTKDLPLDFF
VCFSSMASALGSLGQGNYAAANAFMDALMHQRR-ALGQPGLSINWGSWASVGMAATPQHRKQAAARGIHTLPTPLALAALGVLLRG-PQAGVAAIDWERF
IRQVRLGI----------------------PLKLIEVLVASAS-------RG---------SSAP-AESPELFRARLRE--------APPLQRRELLLFM
RARMLGFAKIDPHHRLVELGLDSLSSVELKNHLEITLGCSLPAALLFDFPTLDALAVHLHDE----------
>tr|Q091C2|Q091C2_STIAD CrpB-like protein OS=Stigmatella aurantiaca (strain DW4/3-1) GN=dkxH PE=4 SV=1
----------------GLDSDFSEWMYRMTWSPCDAAEKRPSGQQHWVIFTDEGGFGNELMALLSQRGRFTPVRKGREFSSSPDGF-QLNPEESGHFKSL
IASCG--NEPVSGFLYLWGLDGSSNEEPSLGLEAAQVTGCVGALYLTQALARASWSARLILVTRGTQRLASDQGPRIAQAPLWGFGQAVATELPELRCLR
VDLAAE--PRLGD-LGTFIRALS-PGSEAQLAVRNGALHAARVERTRLRTGAA-KKVAISAASSYLIAGGLGGLGLRLARWLVDRGAQYLVLLGRSGPSP
EA---QRQIEALEA----KGVRVQVALADLASHEEVAAVLAGLR--SAPPLRGIFHSAGVLRDGTIGNQTSGNFHEVLAPKVQGAWNLHLLSSGMELDFF
VCFSSVASLIGTPGQSNYVAANAFLDALAHLRH-AQGKPAITINWGSWAEAGMAARRAEAGRPGTLGFGAIPVEQGLSVLEQLLGS-HQLGVFPVDWTRL
TEQLPGLA----------------------SQALVRAFVRGVP---------------------L-QNQPPVFLQQWEL--------APPNRRMELLRHV
TAVTLGMAKISGGERLFELGVDSLLAVELKNRLASSLGKSLRSTLVFDFPTVNGLVAHLAGE----------
>tr|A0A0F7BMD0|A0A0F7BMD0_MYXFU Polyketide synthase OS=Myxococcus fulvus 124B02 GN=MFUL124B02_24080 PE=4 SV=1
----------------GLDVDWQDWLYRVTWRPCASQDERPT-GQHWVLFIGDGGVGDTLAALLEQRGRVTRVRQGR--TLD--------PARPDSFDRL
FSEWD--GAAPHGLVYLWDDDE-E------------ASSCEGALHLVQALVRASWTPRLIIITRGTQTLSSDHEPRIAQATLWGLGQAVSTELPELRCLR
VDLPRE--PAKGE-AEACLRAFA-AEQEQQVVVRTEGLYTARLERARARAVT--RKLELSSEASYLVAGGLGGLGLRLAGWLADRGARHLVLMGRHGPSA
EA---QRQLDALAT----RGVHVRVALADLASRDELAAVLAPSN--DAPPLRGLFHAAGVLHDGTLAHLTAEHFREVLAPKVQGAWNLHVLTAGMPLDFF
VCFSSAASLLGTPGQSNYVAANAFLDALAQLRR-AQGRPALTLDWGSWAETGMAARPVSTRSPTALGFGAIPVERGLEVLERLMGG-SSLGVFPVDWTRL
AEQWPGLS----------------------RQAFFQGLLGGTP---------------------M-EPRAPAFRARLDA--------AAPNRRLELLRHV
AARTLGLARLSGGERLFDLGFDSLLAVELKNRLAGSLGKSLRSTLVFDFPSVAGLVTHLAGE----------
>tr|L7UED9|L7UED9_MYXSD Polyketide synthase OS=Myxococcus stipitatus (strain DSM 14675 / JCM 12634 / Mx s8) GN=MYSTI_06013 PE=4 SV=1
----------------GLEVDWREWLYRVTWSPCASPEARVS-DPHWVLFTDEAGFGEEVAALLEQRGRVTRVRQGSEFLQGPTGF-QVDPARPAHFEQL
FSTWD--GASPQGLLYLWGLDAGDSLE------SAQRSGCVGALHLVRALAQRSWAPRLVIATRGTQALPADQGPRIAQAPLWGFGQAVSTELPELRCLR
VDLPGE--PVPTD-AEALLRACA-PEQECQVAVRTGALHTARLEHARPRAMS--RKLEVSPAASYLIAGGLGGLGLRLAGWLADRGAKHLLLLGRRGPSP
EA---QRRIEALEA----RGVHVRVAQADLASRDAVAAALSEAR--GAPPLRGLFHVAGVLHDGTLVHQTAEQLHEVLAPKVQGAWNLHELSAGLPLDFF
ICFSSAASLLGTPGQSNYVAANAFLDALAHLRH-AQGLPALTLNWGSWAETGMAARSAAEGTSSAMGFETIPVERGLEVLERLMGG-GSLGVFPVDWRRL
GEKWPGLS----------------------RQAFFQGLLGTTP---------------------H-APRAPVFRAQLEA--------AAPTRRLELLRHV
SSRTLGLARLSGHERLFDLGFDSLLAVELKNRLASSLGRNLRSTLVFDFPSVAGLVSHLAGE----------
>tr|F8CN03|F8CN03_MYXFH Polyketide synthase type I OS=Myxococcus fulvus (strain ATCC BAA-855 / HW-1) GN=LILAB_29640 PE=4 SV=1
----------------GLDNDFQDWLYRLNWTPSAVTEDHSS-SAHWAIFASEDGFGSELVQVLSRRGRCTLVRKGEAFSSTAQGF-HVNPSSPEDFARL
AQGWA--HQPPTGVLYLWGLDDAGGDADAR-LDAAQESGCLGALRLTQALTRGA-GTRLVLVTRGTQRLPADHGVRVAQAPLWGFGQAVATELPELRCLR
IDLPAE--PRPED-LGTFVRALA-PDAESAAAIRGGSLFTPRLERARSRAASS-RKVPMVADATYVVAGGLGGLGLRVATWLADKGARHLVLLGRSAPSP
ES---RARLDALEA----QGVEVRVAQVDLASRGAMAELFASLR--DAPPVRGIVHTAGVLRDGTLANQTPEQFREVLAPKLQGAWNLHALSEGLALDFF
VCFSSAASLIGSPGQSNYVAANAFLDALVHLRH-AKGLPALTLNWGSWAETGMAARRAASARPGAQGFGSIPVEQGLGVMERLMGG-QQWGVFPVDWARL
AEQLPGLA----------------------RQALVQGLLGSVP---------------------R-RVQAPAFRAQLDA--------APENRRLELLRHV
SAATLGMPRLVGSERLFELGVDSLLAIEIKNRLASSLGRSLRSTLIFDFPTVNGLVAHLADE----------
>tr|A0A0H4WS89|A0A0H4WS89_9DELT Malonyl CoA-acyl carrier protein transacylase OS=Myxococcus sp. (contaminant ex DSM 436) GN=A176_002591 PE=4 SV=1
----------------GLDGDFQDWLYRVAWAPRAVPEEQGA-GQHWAVFVNAEGFGSELVQVLTQRGRCTVIRRGETYSQGAEGY-RVNPSSTDHFERL
VQDWA--HAPPTGVLYLWGLDEGPVSPGTLHLEAAHVSGLTGALHLTQALARSA-AARLVLVTRGTQSLASDQGARVAQAPLWGFGQAVATELPELRCLR
IDLSAE--PRAED-LGAFVRALS-PGEESSAAIRDGGLYTARLERARLRASSA-KKPAIVADAAYVVAGGLGGLGLRVALWLAEKGARHLVLMGRNAPSA
ES---RAQLDALAA----KGVQVQVALVDVTSRDAVAELFERLR--SGPPVRGIFHSAGVLRDGTLANQTSEQFRAVLAPKVQGAWNLHELSARMALDFF
VCFSSAASLIGSPGQANYVAANAFLDALAHLRQ-AEGKPALTLNWGSWAETGMAARRAASVRPGAQGFGSIPVEQGLSVLERLLGS-QQWGVFPVDWARL
AEQLPGLA----------------------RQSLVQGFISAVP---------------------Q-RAPAPVFQVELDA--------APANRRLELLRHV
SATTLGMPKLAGNERLFEVGVDSLLAIEIRNRLASSLGRSLRSTLIFDFPTVNALVAHLAEQ----------
>tr|S9NT03|S9NT03_9DELT Malonyl CoA-acyl carrier protein transacylase OS=Cystobacter fuscus DSM 2262 GN=D187_009447 PE=4 SV=1
----------------GLDSDFMDWLYQLTWTPHAATEERPA-SQSWVLFADEGGFGAELMEVLTQRGRCTLVRRGHEFSSGPDGV-RLDPGSAAHFSQL
LSAWE--GEPPTGLLYLWGLDEDLDTGFSLGLEAAQIPGCLGALHLTQALGRTSWATRLVIVTRGTQRLPSDRAPRIAQAPLWGFGQAVATELPELRCLR
VDLAGE--PRREE-LGAFVRALF-PEGETQVAVRGGALYTARLGRARLRASPE-KKSAISAEASYLIAGGLGGLGLRLAVWLADRGARHLVLLGRRGPSP
EV---QGQLEALEA----RGVRVQVALVDLSSREEVAEVLNGMR--STPPLRGIFHSAGVLRDGTIGNQTAEHFREVMASKVQGAWNLHELSAGLELDFF
VCFSSVASLIGTPGQSNYVAANAFLDALAHLRH-AQGKPATTINWGSWAEAGMAARQADTGRPGALGFGFIPVAQGLSILERLLGG-SQLGVFPVDWTLL
TQQLPGLA----------------------SQALIQAFVGGVP---------------------L-REQPSAFRQQLDA--------ALPNRRMELLRHV
EATTLGLAKIAGGERLFELGVDSLLAVELRNRLMSSLGRNLRSTLVFDFPTVNGLVAHLAGE----------
>tr|Q1D4F0|Q1D4F0_MYXXD Polyketide synthase type I OS=Myxococcus xanthus (strain DK 1622) GN=MXAN_4298 PE=4 SV=1
----------------GLENDFQDWLYRLNWVSRAVTEEHSA-NQHWAVFASEDDFASDLVQVLSQRGRCTLVRKGESFSSTPEGF-RINPANPEDHARL
VKAWA--NQPPTGLLYLWGLDEGGHAGDAGRLDAAQELGCLGALRLTQALAHGQ-GARLVLVTRGTQSLPSDHGARVAQAPLWGFGQAVATELPELRCLR
IDLPAE--PRSED-LGTFVRALA-PDGESGAAIRGGGLYTPRLERARSRSVAA-KKVSIIGEATYLVAGGLGGLGLRAANWLAAQGARHLVLMGRSAPSP
EA---RAQLDALES----QGVKVRVARVDIASHDAMADLFASLR--EAPPVRGIIHSAGVLRDGTLANQTSEQFREVLAPKLQGAWNLHALSQGMALDFF
VCFSSAASLIGSPGQSNYVAANAFLDALVHLRH-AEGLPALTLNWGSWAETGMAARRAASARPGAQGFGAIPVQQGFSVLERLIGS-QQWGVFPVDWTRL
AEQLPGLA----------------------RQALVQGLLGSVP---------------------Q-RAQAPAFRAQLDA--------APPNRKAELLRHV
ASATLGMPRLSGNERLFELGVDSLLAIEIKNRLASSLGRSLRSTLIFDFPTVNGLVAHLAEE----------
>tr|A0A089LDE5|A0A089LDE5_9BACL Uncharacterized protein OS=Paenibacillus borealis GN=PBOR_19450 PE=4 SV=1
--------------------------------------------------------------------RCIQVQAGAEYARLSS-TEYVNPGQAADYRLL
E-ALNTQGVELQHIVHGWNVNGGAGAGAGDAL--EDTDSLQEGLAEFLEAQMDQGLYSLLHLLQAAAYDSAEHVLTPLNEMAAGLAHSISADHPLFQLSL
VQLNAEAPAEAAELVQ---ELLPPQAGGTEIRYDGGARYLRKLLPQ---LHQA-GESRFIRGGVYIITGGTGALGMLVAAELAATVQARLVLAGRQP---
VDAAIQAKLEHLAG----LGA-AVYLQADVADMDSSVRLIGQAKARFG-GINGILHCAGIGETVKAAESSKAGFARILGPKVSGTLNLDLASKDEALDLF
ILFSSTSAQIGDMGAGSYAAANSFLDRFAVYRDRLRQGKSVSINWPLWQDGRYQVVAAQQQVLAYYGMHLLDSRTGLDILEAVLKEDVVQAFVGYG----
-----DPHK------I--------GQ-------TGQAGQA-------------------------------ATA--AQSASSSVDSGELLVRTQAYLVSL
LAKTLGIERIGQASPLDAFGLDSIMILELNESLQREFS-GLPTTLFYEYNTVESLAGYFTGH----------
>sp|P40872|PKSM_BACSU Polyketide synthase PksM OS=Bacillus subtilis (strain 168) GN=pksM PE=1 SV=4
--------------------------------------------------------------------SFVDIRPA--------------------DEAI
ADKLQAYG--SIDHVLWIAPSHRGSIGSDGQE--EAVLHLFKLVKACLQLGYGEKQLEWSLVTVQAQHE----AVQPAHASIHGLAGTMAKEYPHWKIRL
LDLEKGCTWPVNH------FALPADLGHA-WAYRNQQWHQQQLI-----SSLS-GDTLYRKGGVYVVIGGAGYIGEAWSEYMIRRYQAQIVWIGRSQ---
LNAAIQSKIDRLSA----LGP-PFYIAADAADKHSLQQAYEQVKKRHP-HIHGIVHSAMVLFEQSLEKMKPEEFTAGLAAKIDVSIRMAQVFRQENVDFV
LFFSSLVAHIKNVKQSHYASGCTFADAFAHQLSQS-ACPVKVMNWGYWGNSEAAEDEHY-VQLMQIGLGLIEPAEAMKALEALLSGPVSQTAFIHTTKPV
ATSAGIFEKLKPYCYTDL----SEGFESVFIVA-------AS---------------------SNGLVKNVIL-PE---EAGQSKHALLREKSTEYMKKL
IGETLKIGKIESSEPLEKYGIDSIVVVQLTNTLRKEFD-HVSSTLFFEYQTIDALVEHFIKT----------
>tr|V5DH19|V5DH19_9GAMM Polyketide synthase PksL OS=Methyloglobulus morosus KoM1 GN=pksL PE=4 SV=1
--------------------------------------------------------------------LKVALGNGIDHQQASG-KIYINSLDAQGYSRL
GGFLDEKKIDVSHIVYLWDSTHQATMLELPEQTQQALTLLFHVDKSLLHATKTLKQLFVNLC-------EPNTAQWVIEGSITGFLQSIGTEYPKTTHKV
VSIEAKEIERVAWDNA--LKELLYSEKNTWVQYGQDSDSRLIWRLHGIDRFH---LSALKQGGTYLITGGMGGIAKILASYLVQNYR-NLILLGRSA---
LQSEGESFIQDLKS----SSTDIAYLEVDIGNLDRLGQAFADAKQRFG-TLNGVFHSAGVLEDNLLANKAIDSLQKVLRPKLQGTVNLDQVTQSEQLDFF
LVFSSLTAILGNPGQCDYGAANGFMDAFIAHRKKLRYGSSLTINWPFWNEGQMGQDNDVLSLLDSFGLPL-DKVEAFGCLEEALHFGGSQIAVI------
-------K--------KEKEFSKPSI--------KQKNVS--------------------------------KVP-ERSTIN-ITVDQIISRLSIDTRRL
VAELGKFEQISTQSDFMALGFESVVLAKLANMLNKKYALKISPAVFFEHTNLEKLNAYLLDE----------
>tr|Q2T4P0|Q2T4P0_BURTA Polyketide synthase, putative OS=Burkholderia thailandensis (strain E264 / ATCC 700388 / DSM 13276 / CIP 106301) GN=BTH_II1665 
-----------------------------------------------------------------------AER---------------RIVGADAFRE-
--VAAALG--AVDAFVWIAPRAARGGALADSPALDCAANCFEWIAALLAAGAANRAIDALFVTSGCADD----PGDPAHAAIAGLVGALAKEHPRWRVRI
ADHASAEPAPVDAL-R-----LSPDQGDA-LAYRDGQWLRR---RL---ETMG-EPAAHRAGGVYLLIGGAGGLGVVYSEYLIRRYGAQVIWVGRRE---
RDADIDAAVARLAA----LGP-PVYRRADAADPAALRAVCDDARARFG-ALHGVVHAAMVLADRSLARMTQQTLRAALVPKIDVARSMAVLLPAADLDFM
LFFSSMNAFTTQPGQGNYAAGCTFVDAFAHALRAQ-ACAVKVVDWGFWGSAGAVATPYF-RARMEAGIGSIEAPQAMRVLERLLAGPHGQLAMIHAIRPT
MTSARALECADRYRYTDV----SAGFHSIAAAGHGQTIVCAS---------------------SDGVVADATGA-DPDADTDADADARLRDAASAWLRAR
IGAALDIDDIDSRETLERYGIDSITVLQLTKRLRDAFD-DVPNTLLFEYNTVDALVDHWLAT----------
>tr|E9KSM3|E9KSM3_9PSED Polyketide synthase OS=Pseudomonas sp. 2663 GN=fr9F PE=4 SV=1
-----------------------------------------------------------------------VFGSNEAVRAALEGTRTVLDGTDDAFTLK
AYAETARA--EAPHLLWISGGGENPDLDPDALISRGILPLFRLINALIEAGLDSVPLALTVVTRRLDET----DNDISDAGVVGLVGTVAHEYPHWTVRH
WDVDAPVDDGRFFRLDTHL-ITTAGDGDV-RVHRGGRWHRQRLARV---DEGR-ADPVYREGGVYLVIGGAGGLGRTWSRHMIERFGAQIVWLGRRA---
PDDEIRAHLAALSA----LGRGITYLQADATDAVALKRARAAIMEQFG-ALHGIVHAPIVLADRSLARMDETAFRLSYDAKLKTCANLYPLFAREPLDFV
LFFSSLNAFSRSAGQGNYVAGCTFTDAYARKLDTR-ACDVKVINWGYWGDVGIVAGARH-RERAAAGLDSISAEDGLRAIDALLARPGSQVAYVRTARPI
ATTDGLLRRLEPYCYTDV----SEGLRPLGQHALGQQIIVFE---------------------SDGVVTADAS--P------TVSEEMRFNGALAFVQRL
VADTLKIDELPPDEHFQSIGLDSILVVQLTNQLRRYFD-GITSPLLFKVSTVRALTEHLWLA----------
>tr|A0A0K9M637|A0A0K9M637_9BACI Uncharacterized protein OS=Bacillus sp. FJAT-27238 GN=AC624_02140 PE=4 SV=1
-----------------------------------------------------------------------PAAP-----S-------IDT------EEM
AHKLRACG--EFEHLLWIAAREPVGVAASDAPIEKGVLHVFRLVKALLELGYGSKRIALSFITQQARDD----AVRSSAASVHGLAGAIAKEYPLWAIRV
VDLEAGGSLSFDQ------FRLPADEGHV-WACRDNRWYRQRM------AAIP-KQSLYRQGGVYVVIGGAGGIGEAWTEYMIRQYRGRVVWIGRKP---
LDETIQHKIDRLGA----AYGEPWYISADAKDKQSLQRSVDEVKSRYG-AIHGVIHSAIVLLDQSLANMDEARFRAALSAKVDISARMAQVFATEQLDFM
LFFSSINSYTKPAGQSNYASGCTFKDAFAHRLGKE-PFPVKVMNWGYWGSVGVVASEEY-RKKMSLGVASIEPDEAMAALELLLGGPLDQLVMLKMTKPV
PTSAVVLKRLEPYLYTDL----SEGFRSIFGAA----VIAAE---------------------SDGVYCGNASVPSSDG-AGDVSDRALGSFIQTVIRTA
VADALQIGRIQDDRSFSDYGVDSIIAVNLINIMNEHCGTQLQTTIIFDYNSVERLSDWLLRE----------
>tr|D6AGV0|D6AGV0_STRFL Polyketide synthase OS=Streptomyces roseosporus NRRL 15998 GN=SSGG_06419 PE=4 SV=1
--------------------TIDSWLAEPVWTDCPPLPAEPPRDVSWLLLADTGGLADAFAALADAGERCRLVRRGAAYTASDGRTSTVDPASDADLRRL
FADLDRDGPFRGTVLHLWNLDAPAASCDRTALGDHTGAGAYSLIVLARLLSARGAGGRLHIVTRGAQPALPGEAPEPLGAPAWGIGRVLDHPGKLI----
-DLDPRRHPGDRAEAEALLAEALSD-DEAEIALRDGGRRTGRLRPAELTRPL---PPRLRADGSYLVTGAFGALGRLLCRTLVRRGARRIVLVGRTPVPG
TDPAEGRAVALLRE-LETLGAHPVPATFDITDEDALTGWLDAHRRSGAPPVRGVFHLAGQVRDTLVADLDRAAFDAVHGPKTVGAHLLHRHLRDEPEFVL
FASIASLLTTAGQT--NYAAGNAFLDALAHHRR-AQGLPALSLDWGPW-ATGMIEELGADHYLNSRGMSSLSPEAGMAVLERVIGQDHAQ----------
---LVVATVVDWPVFLAWYP----------------S-PPPLVADLA--------AAAAPPA-D--TASGNGFLDTFRT-----AGEEARALVTERFAAL
AATVLRTGRIDPATGLGELGLDSLLAMELRARIHAELGVALPVVALLSGSPTGELADRLH------------
>tr|A0A099KPM6|A0A099KPM6_COLPS Amino acid adenylation domain protein OS=Colwellia psychrerythraea GN=GAB14E_3044 PE=4 SV=1
--------------------TIDSWLYDINWLAQPKQVSEEIDSQQWLILADDAGIGQAVAQSLIAKQPCCLVSVGEYFDYDEQNHAWLVPDSKDHFLQL
FDTLGKD--NIRGVVHCWNLDTPDDSLDIGQIQRAKRLAIHSALNLTKAINTANVKFPLYFITRDASQAPATNKANVLSGSLTGFCRVLQNFGRLI----
-DVDGINDV--------IVTELNADSTEHEVAYRDNEAFVPRLEQAQLQTPF---PTVLKSDAAYIITGALGSIGQLVCQLLIDRGAKSLILVGRSKFPS
LTPDSYERILFIRS-LEKQNINITLWNADITRERDLKRCLNEYAQKDSPIIRGLFFCAGVVKDTLLDKMDTAAFDAVFDTKALGAVMLHRALSKTQDFVL
FSSVAAQVTTAGQT--NYATGNAFLDSLAHARR-QDDLPALSINWGPW-AIGMIKELNADHYKNQRGMNCIQPFSGMAVLDRIIDLDNAQ----------
---LMVC-DADWSVVTNWYE----------------G-KPSLFSHLS--------QKKSGSQ----NDKKQAFGPLYQQ-----TEVVQQVLVADHFASA
VSHVLRCKQVELDLSLGNLGIDSIMATELRNKITTHFGETLTIVRLLSGATVNELSAELN------------
>tr|U1LKX8|U1LKX8_PSEO7 Polyketide synthase module-like protein OS=Pseudoalteromonas piscicida JCM 20779 GN=PPIS_01931 PE=4 SV=1
--------------------TIDSWLYQVNWLAEPEQEIQTDTSGRWVLLADQSGTAEQVADRLAKGHSSCIVKSGEYFDIDGHCHAWLVPDSRDHLSQL
IETLGKQ--EIRGVVHCFSLDNSAESLTLAQLQRGKRHSLHSLLNLAKTVVEQDCKFPLYVVTRNASLVNSEQLTAVMSASLTGFSRVLDNWGGLI----
-DVDGQNDA--------ITARLLSDRQEGEVAFRENQAYVARLEQATLQSAF---PTRVQSHKAQLITGAFGSIGQLVCQLLVDRGARNLILLGRSQLPE
LTSSNYDRVRFIQH-LESQGVNVSLWQTDLTRERELHAALESYHLSAQAPINGLFFCAGIVNDTLLGNMDTRAFDGVFDTKAIGALMLHKALSKVDEFVL
FSSVAAQVTTAGQT--NYASGNAFLDALAHYRR-NQGLPALSINWGPW-AIGMIEELGAEHYKDQRGMNCISPSAGMAVLERILDQDQPQ----------
---LLVC-DADWSKVTNWYA----------------G-KPSLFSHLA--------TQENDKQ----SHQEQDFAPLYQQ-----TDSALLPLVADHLANA
VSQVLRCKQVELDLSLGNLGIDSIMATELRNKVTTHFGETLTIVRLLSGASINELSIELN------------
>tr|I9NJT0|I9NJT0_9FIRM Amino acid adenylation domain protein OS=Pelosinus fermentans JBW45 GN=JBW_00295 PE=4 SV=1
--------------------TIDNWLYDVQWQEQERSIVGGKDNSGWLIFADKQGVAEELLGLLKQGEYCCLVYPGDGITINSNSLATVASDTDGEVSSL
IKTIFKDNRKCKGIVHLWNLEAPSESMELADIEKIKKLGCYSILQIARAIGDLEIPAKLWIVTRRAQVVGEDTGDCAAASPVWGVGRVLGNWGGLI----
-DLDSVASP-LKQDALNVFNEMISGDKEDLIAFRGEKRYVPRLHYASLTKPL---PTRFRSDGCYFITGAFGALGQLVARTMVKHGARRLILMGRTKIPT
VQPGNAEKIAFIKE-LESLGADVLLASVDITNELQVAEYFKQFKEMGYPPIRGIIHSAGTVNDKFVSKMDAKTFDSVYDPKVYGSFLLHKYLKDEPEFVL
FSSVADLVTTAGQT--NYAAGNAFLDALAHHRR-ANGLPALSINWGPW-ATGMVKELDIEHYRLRRGMNCILPEVGMNILDRVIGQDVSQ----------
---IMVC-EVDWPLALPWYP----------------S-EPPLFAHLA--------KKEDNKN----DGDNVSFEILFKN-----ADEAFKVIVEEQLTEL
IAKVLRCKQVEPNSSLNALGIDSIMATELRNKIAFHFGHSLTIVKLLSGSTIMQLAEALL------------
>tr|F1T739|F1T739_9FIRM KR domain protein OS=[Clostridium] papyrosolvens DSM 2782 GN=Cpap_3719 PE=4 SV=1
----------------------------------------------KFVILDNTHLYDSIKQ---LGLDAVLVRPGNAKNKISQTEYEICSCEEQDYKWL
FQNAVNNSS-STCIIYNINYAEE----FFVFVKAVVSSGLRSNIKLFHVFSG----D-------IQSANKLSVNP--MYLACAGLLKTAVMEMPKL--VC
---KNIAFDKSIVKLAGYLRDELALGNVEIYYSFEDKRHIRALKELTGTNP---QQSTLKVNGVYYIIGGLKGIGLKFAEYLATTYKANLIISGRTELSA
E------NKKHIENL-QRVCESVLYLQADVNVYQDMKNSVELIRNTYG-RLDGIVYSAGIKQDELIINKTPETFTRIIETKTLGIQNTCKAVGEEPVDFI
ITFSSLAGLMGNMGQADYAYANNYLDAYATVEG-FNGKNMLSINWPYWLDGGMRLDSEIEGMKRRNNMVPLQTKDGLQAFEFAISNLSSV----------
-HQLFVLASDNVTKSQ--------------------EV--KTVKEDSSKS---KEPSGKKSVETKG--V------------------SASESAISYLKNV
ISEETEANRIKNNEAFDAYGLDSVMIMNITVSMEKEFG-ELPKTLLYENHNINELNEYLQTN----------
>tr|A0A0A1FDT8|A0A0A1FDT8_9BURK Malonyl CoA-acyl carrier protein transacylase OS=Collimonas arenae GN=LT85_1869 PE=4 SV=1
----------------------------------------------VLVIADDTSLAETLALRFASSVNVVLAQSGAAFSRLGERRYCFDPANPHSYTEL
LTHLASQDLRPSHITHYTAVD--------HDDVQSLRRGMLSMRHLFNALEQ----T-------MPREAIQPQHD--AISGYARSLLTI---N--H--RF
---ELFTVRAERSLAAMLQNEFEASGAGLIAL-WNGRRYLRSLAPLG-MSQ---NALPLKSRGVYLITGGAGKLGLVLARYLATHYQARLILSGRSERLH
DE-----ALAQIEAL-RAAGADVHYHCSDIAQAGQADALLAVAKQVYG-RLDGILHCAGVASDKLITELDEVAFAELLAPKIDGLLALDRATRSEPLDFF
VNFSSVSAMLGDLGSGAYAVANRFMDSYAVWRG-QCFGKSLSIGWPLWATGGMKIAEDASLF-SFSGMSALTEAEGIEAFERLLRGDM------------
-QQVLL-AVGDAAKIGRALRVHVEQAKTVSAARTTSDSNTAL-------------PSG---ASSDGL-S------------------DQQRRAEHYLKER
LGIVVAASDIGGHTTFEQLGMDSVMLMELRNSLTQDFP-GLPKTALFEYDTPARLAQYLMQQ----------
>tr|C5BIL8|C5BIL8_TERTT Modular polyketide synthase, type I PKS OS=Teredinibacter turnerae (strain ATCC 39867 / T7901) GN=TERTU_1990 PE=4 SV=1
----------------------------------------------LLSVGFEAGQAGELTSA-Y---SGTFT--HLAFSGITEQDNWFAACDEESITDV
LNQLENYRGLPTAILFN-------------ESDDSVQAPLLRLALLIQVLEK----V-------HPNDVATCIGE--AAAGFAKSLLSV---N--H--RF
---RLVTVGAETDQPSLFYIQEAGYTNADVQY-LQGERRVRRLYSASPSSQ---RNLPLEQGGCYLITGGLGKLGLLFARYLAKHYGANIVLTGRSAM-N
DN-----ALKSLVEL-QQLGASATYFPADISDPHATKRLVDHCVKTYG-KLDGVIHSAGVADSKNLLQQSMSDFARIMEPKIAGTIALDQATAGESLKFF
VVFSSISALVGDLGSGSYACANRFLDAYIALR---ASDRGLSINWPLWNEGGMEIEEQRAFF-DFSGIQPLDEQQGLEAFESMLSLPH------------
-ANLLV-ASGEIQKLQQYLRVADALPTLISTDREPAAAMLLTAPADNPKP---QIATP----DGASMSG------------------SPGSALFDFLRDH
VVTVTAVEKVDNHTRFEGFGMDSVMLMELQNNLQKQFN-KLPKTVLFEHDTLAKLAEFLEKN----------
>tr|A0A0J6G723|A0A0J6G723_9XANT Uncharacterized protein OS=Xanthomonas axonopodis pv. phaseoli GN=ACP93_01060 PE=4 SV=1
----------------------------------------------VLVVADDLDLAQGLVRALPDGDRGI----AVAFAANGDASDRFDPFSAASGSAL
FDSLRDRDLLPERIVILWSAG--------DTGTSVLHRGLQSVRQLFVASER----V-------NPDGGVHPQHE--AIIGYARSLLMA---N--H--RF
---ELSTLSDDRDRARAIVDELDVDGGANIAW-RGGRRHRRTLRALAHDAN---AALPLRDGGAYLITGGAGKLGLAVAQWLATKCRAQLLLCGRSAEVP
AS-----AHDALDTI-RALGTQVEYRSVDIADAAAIAAFVAVAEREFG-GLSGVIHCAGSASDRSILELDDAGFNALLAPKVDGLIALDRATASLPLDFF
VAFSSVSALIGDLGSGAYAAANRFMDGYALWRG-LRHGRSLSIGWPLWATGGMEIGGDSVVF-GYSGMQALSEAEGLEILGTLLRSAQ------------
-GRVLV-TVGDPKRIAKTLRLAEGGERIIDAKPVMHDVAIAAPPTVHSEP---QVPPAKYSAVAHTVDD------------------ALGSEVEHLIKQR
MAAVTQASAIGSRTSFEQCGMDSVLMLELHTALRADFT-ELPKTALFEYDSAAQLAHYLLAR----------
>tr|F1T739|F1T739_9FIRM KR domain protein OS=[Clostridium] papyrosolvens DSM 2782 GN=Cpap_3719 PE=4 SV=1
-----------------------SIYCIETWEEQELHKTGTNTEQQEALVFCHK-------DFTK---ERVFKSLGENIIQIHPG---NEFRQINPYELE
LN-LSDESSYMKLYDWLTSN-------------HIEIRLAINCFCLCENKIL-DENVSTFSVDFFFHVLRPVWNATC--AATSAFFRVLSNENSRICCHS
IELSSI----NELCLELINDER--TSKNLEVKYVSEKRYIKKLELTELIDDN---AKFTVWEGNYVIIGGLGGLGTLLASHLITEYNAKVIVCGRNCNYD
LIEE------AKAEIR-KKGGDLVFHSCDITSEESTKKFISQI--AEQGKINGIIHCAATSKDSMIIKKEKQDFDYVINPKVNSIKQVELIAKECRDYIL
Y-FSSIAAYVGTVGQCDYAYGNSFLNNYVSEQK-NLNVRLISIAWPLWESKGMNASKLVKNNMQKQGFDVLSREQGIKVFETVLNSGKSGTFITFYGKKR
EIIDLLGLKQEGNERG--------------------------------------------------SS------------------FMNKEKINLFLKES
IASITKHTDIDDYEYFENLGIDSIKMINIIAKMEEKLGS-LPKTLFFEYERLDQLEEFVEKE----------
>tr|L8PZ48|L8PZ48_BACIU Polyketide synthase type I OS=Bacillus subtilis subsp. inaquosorum KCTC 13429 GN=BSI_21430 PE=4 SV=1
-----------------------RSLYAPVWKESPLPEVLTDGQRCTLLFSDHKRYSEREN----------TFTKGDRFEQISDDVFTINRENPEDYISL
IRLLKQKNAIPDSILHAWADKQS-------EFDEALQTGIYSVFYLTKALIS-ENLINKVR---------EKRLPCF--EGIGGFFKSVKQEYPELCCKA
IRFTNG----SLYESDIYKEIDAAPDHNINIMYKDGVRYAQVLEKKTKTFSP---VQYPGKDKVYLITGGLGGIGSKIAEYCAKS-TCTIILSGRSPLRG
K----------LEYLN-QFNAEVFYMQADISDKETVIKMVDDIM-ERYSGLSGIIHCAGVIRDSFLFQKTNQELSEVIAPKVQGTLYLDNATKEIDDFFA
V-FSSVVSIAGNEGQTDYAYANSFLDHF-RQKS-QRNGRTLTINWPLWKETGMGVSIQARTSLFDSGLEELSSEAGADWFAQIVMSGQLHNIAVC-GDSD
RFEQFMEQRFQTNYTQ--------------------------------------------------I-SDTI----------QLASGDVKIQTRSFLASI
ISAEVGVEEIDHSVHLAEYGMDSVMIHQCNSKLEQALGA-ISKTLLFEFQTITDLADYLIKE----------
>tr|A0A0A1FDT8|A0A0A1FDT8_9BURK Malonyl CoA-acyl carrier protein transacylase OS=Collimonas arenae GN=LT85_1869 PE=4 SV=1
-----------------------QSLYTPVWTTQPIAGATSEGAIEHLLMGDPSDVSWATSQFAS---TRIEH--GSEAAVEDAGALHVRPGRLEDYEAA
VAALVAKGGKLDHVLLIAPRLTSDIAQASDSLDSQVCKSAQNLFSLVKAMMR-GTK-RAKFLHLVSRQPQ---RPEY--QGLSGLYKTLRIEKPSYSGRV
VQCDLA----EQRLAELVFKEFNTADKYVDVSYSGDVRSVRKFRQLDANADL---TASLRKEGVYLITGGMGALGLIFARYLCERYQATVFLTGRSAPTE
Q----------LNELS-SLGGHASFLTCDVVNRDDVRRAVDSIH-AAGHQLNGVIHSAGVIEDDFILRKSPESFARVVAPKTLGTWHLDVETRDEPDFFA
L-FSSVTGVLGNIGQCDYGFGNAFEDYF-RRQG-SRNGKTLSVNWPYWKEGGMRLSDKEEENLHSFGLVPLLSGQGIEIFEYALTRLHSQLVVMP-GDAA
KVQEVLGVVAVPVPVA--------------------------------------------------AVVAAALPAKIAHSQPLLTTGDRSAAVSRYLAEL
FAAQLQI-DFELGRSFREYGFDSIVMIDLVNLMEKKFGS-LPKTLFFEHQTLGELTAFFIEH----------
>tr|C5BIL8|C5BIL8_TERTT Modular polyketide synthase, type I PKS OS=Teredinibacter turnerae (strain ATCC 39867 / T7901) GN=TERTU_1990 PE=4 SV=1
-----------------------DSYYAPYWDLVDTPSVNADKS--VLLVAEHAECETESSLFDG---VRWAS--GADFATLPNNHFTAQGTQLDQLEQV
FASLKAQSLLPERVLFLHHVTAVSDF--SAASLNDATLLAETLFCVVKAAFK-PVR-KLRFVSVAAGN--RDGSPLV--QGLSGFYKTIRLEKPTYSGRT
VLLESL----DKSIQQQIVNELYVDDQRVDLAYAQNQRFAREFYRFNEYEPS---HIGFKKGGAYIITGGLGALGLLVAGYLLETYSAKVYLTGRSPLKD
G----------LREKC-TDGAEVSYLQGDAADFDAVCRWVESIN-ADGHGVNGIIHSAGVIEDNFIIKKSLDAFQRVLGPKVRGTLALDLATKDQPDVFV
L-FSSVTGIFGNLGQCDYGYGNAFEDCF-SVNG-ERSGIAVSLNWPYWKDGGMQLGEKEEEILFNFGITPLSNPSGLAALDFAVTNAIPQMAVLE-GDQS
RVCEVLGVKNAHQSAI--------------------------------------------------ATTQAKTV------SGAQGT-ASKEDVFGFLRKV
FAAELKLDRFDLNSSFQAFGFDSVVMIDMVNALEKTFAG-LPRTLFFEYQNLNDLSDFILAE----------
>tr|A0A0J6G723|A0A0J6G723_9XANT Uncharacterized protein OS=Xanthomonas axonopodis pv. phaseoli GN=ACP93_01060 PE=4 SV=1
-----------------------GDLYAPLWVRAAIPSAAQAPA--MVMIGEREDLDSRSPRFAG---TSFERAAGAGLAPE-EQGNALRAGSLADAEAA
IGAWKARGAQLEYFVWVAPKPSEN-----LSVQARIDAGARTVFALVKAMLR-GPK-RARFVHLNHWDIDGLGATDV--IALAGFYKTLAIEKPSFSGRV
VQCPTD----S--WADLVADELLADDKVTDVRYRNGLRETRRFASVHSST-G---STDFRTEGAYLITGGLGALGLIVARHLCERYRATVYLTGRKPLSE
A----------LEALA-GLGGRAMYFACDITDRDAVRQVFATIRRQHDQVLNGVLHSAGVIEDDFLLRKPAEAFARVIAPKTLGVWCLDQETQHDPDLFV
L-FSSVTGVLGNVGQSDYAFGNAFEDAF-VADG-QRSGKSVSINWPYWQDGGMRLGEKEEEALQSFGIVPLTTQRGIEVLDYAIAQAQPQVVVMPAGDIH
KVREVLGVIAEDRQPA--------------------------------------------------APSIAIAASPG-EGHADDAPSNWHALTSSFLANL
FASQLGI-DFEPERSFKEYGFDSVVMIDLIADLEKSFGT-LPKTLFFEYQTLGELSGYFIEH----------
>tr|A0A0J1EY99|A0A0J1EY99_9BACL Uncharacterized protein OS=Paenibacillus sp. VT-400 GN=EL84_29080 PE=4 SV=1
-----------------------------------------------------------------------------------------------DYIQL
LDDM--KGQGLTRIIHGFTLAENDSDDYLEQLKLSQDRGIQSAFYLTRAILHVTEGLQLQFISSLANAVYESQV-RPENATLNGFAKVIEQEYPEISCRF
IDVDSD------TDADTIYAELNSSHDRFQVAYRHNQSYVEELDIANILEAS-HEEVTIRENGLYLIAGGTGGIGLQFAKHLADERSIRLALISRTAMPD
WDKEMIERMKTIMELE-AGGSSVELISADISDLEQMTQVVQGLRTKYG-QIHGVINSAGVANDGLIIRKEETAFQEVLRPKVQGTWVLNQVTAQEPLDFF
VMFSSGISMLGEPGQSDYVAANCFLDSFASY-RANGSGRTLTINWPAWKETGMAARFGLN--VD-TAFKTLATHQAISAFDMVLSRRIRRVLIGE-----
PNYASE-L--LPLLESSRVIQFS----------------EAMTARIQQER-NHLNYHNQLTRTEY---------EQKVELHGRD--NGIYTTTEKELAQL
VGHVLGFTGLDVYDNLFELGVDSISMMRIITEIRVRYHVHLNYHTFFEGMNLAKLAIHLIGALKET------
>tr|V5WUH4|V5WUH4_PAEPO Polyketide synthase OS=Paenibacillus polymyxa CR1 GN=X809_05725 PE=4 SV=1
-----------------------------------------------------------------------------------------------SYLRL
ILGA--EGQVLVEIKRGVTFTKMSDHAYFDHRRLLNGQSMVQLFHLAKAIAEKSAVKELTVIAEQAYKVLENEL-KPEHAGLFGLARVIGQEYPDLSCRC
LDIDTS------TQPSELIHSLR-DDDTFLVAWRNGERYVEQIEPVDLTESE-VDPITIRPQGTYVITGGTGGLGLAIGKWLASKGQVTLGLIGRKPLPP
WEARMQNTVTALLELE-QQGAQVEYYAVDVADETAMKQALNELRHKYG-AIHGIIHAAGVAGDGFMALKSQDRFTEVLAPKVTGTHVLDRITTADTLDFF
ILFSSVTSLMGGPGQSDYTAANAYLDAFAEW-RNHSGRRTLAINWAPWQEVGMAFEHKVD--FQESLFQALSTQEGLAALEQLLLHPVPRVIVGG-----
LNYAQV-A--A-LDSAAIPFGFS----------------HEMRAILDRHR-RLLHDHAVTSSAAV---------RRPVQLRGRA--TEQYSSSEKVIASI
WAEVLGLDELNIYDSFYELGGDSLIASKMVGQMNQSLSKKVDMSDIFNYMTVSELALYTDGEAKQP------
>tr|A0A0F6EWS4|A0A0F6EWS4_PAEPO Uncharacterized protein OS=Paenibacillus polymyxa GN=LK13_18685 PE=4 SV=1
-----------------------------------------------------------------------------------------------SYLRL
ILDA--EGQVLVEIKRGASFAKLSDHAYFDHIHLLSGQSMVQLFHLAKAITQKPAVQELTVIAEQAYQVLENEL-QPEHAGLFGLARVIGQEYPDLTCRC
LDIDTN------TRISDITHSLWGNDDTFLTAWRNGERYVEQIEPVDLMESK-ADPITIRPQGVYVITGGTGGLGLAVGQWLATKGKVTLGLLGRTQLPP
WETRMLNTITALLELE-RQGAQVEYYAVDVADEAAMKQAMNEFRHKYG-AVHGIIHAAGVAGDGYMALKSQDRFNEVLAPKITGTHVLDRITASDTLDFF
ILFSSVTSLTGGPGQSDYTAANAYLDAFAEW-RNQSGHRTLSINWAPWQETGMAFEHKVD--FQESLFHALSTQEGLAALEQLLLHPVSRVIVGG-----
LHYAQV-A--A-LDSTAIPFGLS----------------HEMRAILERHR-RLLHNHAVMSSDAV---------RRPVQLHGRG--TGEYSSSEKVIASI
WADVLGLDELNIYDSFYELGGDSLIASKMVGQMNQSLSTKVDISDIFNYMTVHELALYTDGEAKQP------
>tr|C3HA41|C3HA41_BACTU Beta-ketoacyl synthase OS=Bacillus thuringiensis serovar huazhongensis BGSC 4BD1 GN=bthur0011_53580 PE=4 SV=1
-----------------------------------------------------------AKQLRVDGKSVIEVELGKQFSKISNWKYTI-RGEQEDYDKL
FEAIENENIN--QIIHLMTINNETDEE-LLQLQKKLSIGLESLFYLTKSIMKNTNSMELLLFTDFAHRVNGEEFIKPHNAAFFGFGKVIEKEYPKLSVRC
IDIDDK------ICVEDCITEINSKKQVELVAYRDKDKYVQELQNVDIKALPEE-KVEFKKDGVYVITGGMGGIGLEMAKYISSKENVNLILIGRSGLSA
TASEIAYKI-KTINEIQESGSRVECYKANVANEHEIKEVFREIR-KKFNKIDGVIHGAGVSGEGFIFRKEKEVFDNVIKPKIHGTWIMNQLTKDDQLDFF
IMFSSITSLGGSMGQADYAAANAYMDSFEEFRSLVVEQKTLTINWCGWNDVGMLAEYIDEEHKDNNGFKTINSIEAIYTFDEIIQKEISKVIIG------
---EIDYKVLGVHKGLI---KFL----------ISSDILQRIDQTVSKE-----------KISEEMNFVRVNH---ID-----------YNSIENKILKV
WIKVLGLEQIGIDDKFYDLGGDSISAIYLMKEIEKEFPSRIDVSDIFTYPSIREMALYIESE----------
>tr|A0A0K6LN53|A0A0K6LN53_BACAM Polyketide synthase PksN OS=Bacillus amyloliquefaciens GN=pksN_1 PE=4 SV=1
-----------------------------------------------------------IRRLELEGKTVIVAEQGDYFSKIGSHHYTV-SDAQEDYDCL
VKALQSEKVS--QIVHLMSISNEKDKN-IYQLQKKISSGVDSLFYLTKSLVENTNNIELMLFADLAHQVSGEEPINPHNAAFFGFGKVIEKEYSRVSVRC
IDLDQN------LMAESILFEINSKKQSELVAYRDRHKYVQELQTEDLSVIREG-KISIRKNGVYVITGGMGGLGLEMAKYLSSKENVQLILIGRSEQQI
NMEKNNKKI-DALKEIKESGSKVDYYKADVANESEMIHVFEEIK-SKYNTIHGVIHSAGVSGDGFIFRKEKKVFDNVLRPKVNGTWILNELTKHEHLDFF
IMFSSITALAGSMGQADYTAANAYLDSFAERRQRRRDEKTVTINWCGWSDVGMLAEYIENEHKDENGFKTITSAEAIRAFDEVMQKDIRNVIIG------
---EIDHRVLELNQDQI---HFR----------LSPDILTFKEQAIVKK-----------SVESK----TDQT---FS-----------FSDIENKLMKA
WIKVLGLEQISITDKFYDLGGDSISAIYLVKEIEKEWPSLIDVSDIFTYPSIKEMSTYLESH----------
>tr|W4B2Z6|W4B2Z6_9BACL Beta-ketoacyl synthase family protein,phosphopantetheine-containing protein OS=Paenibacillus sp. FSL R7-269 GN=C162_28829 PE=4 
-----------------------------------------------------------IESLRREGRRVIEAVPGQGFSELDAQKYSI-GGQQEDYDKL
LDAIKSQRMS--QIAHLMAIHDQADDD-LQNLESNLKLGLDSLFHLSKSIVKYTYPVELLLFTDRAYRINGSETVHPHQAALLGLGKVLGKESAKLNVRC
IDIDKG------TSSADCICEIKANKQVELVGYRAGVPYVQELQAVHLPALPDQ-EVEIKRDGVYMITGGLGGLGLEVAKYLTSLEKVNLILIGRSGLSD
REDSNQYKT-MVLNQIKANGSNIAFYKVDVADITDMQSVLVQVR-QRYGRINGIIHCAGVAGEGFIFNKEKEVFGRVTRPKIQGTWILDKLTAEDRLDFM
VMFSSINSLNGSMGQADYTAANAYLDSYSEYRKLSKGHKTLTINWCGWKDIGMLVDYKDQEEQNEQGFKNIGTQEAIDALDAVLNKDISNVIIG------
---ELDHKVLGLHKDQI---AFS----------ISPEITAIIEKFLPKT-----------PRQAAGSPAGMEF---KD-----------YSRIEDAVVKA
WVKVLGLEEINVADKFYDLGGDSISAIYLVKEISQVFPSLIDISDLFTYPSITEMSHYIHSR----------
>tr|A0A0E4CZ51|A0A0E4CZ51_9BACL Beta-ketoacyl synthase OS=Paenibacillus riograndensis SBR5 GN=PRIO_5824 PE=4 SV=1
-----------------------------------------------------------IASLRQAGKKVIEAIPGQAFSERGEQAYSL-GGRQEDYDKL
FAAIELQKIS--QIIHLMTIQDHSEGG-HQQLEYNLKLGLDSLFYLSQSIMKHPDPVELVLFAEHVHRISGSETVNPHHAAFFGLGKVLGKEYSKLNVRC
IDIDGE------TRAAECIREINGEKQVELVGYREGRPYVQELQAVPVPALPDQ-QAEIKKDGVYIITGGLGGLGLEVARYLSSLAKVNLILVGRSGLSH
PIDPNHTRT-EIMNHIRANGSNVDCYQADVADEREMQAMLAQLR-QRYTSINGIFHCAGVAGEGFIFRKDKAAFDRVTRPKIQGTRILDKLTAEDKLDFF
VMFSSITSLSGSMGQADYTAANAYLDSYAEYRSLIKEQKTLTINWCGWKDTGMLADYRNEENQNEQGFKNIGTREAIEALNVVLNKEISKVIIG------
---ELDDKVFGLYKDQI---TFS----------LAPEIAARIRPTRPKA-----------PGHTGLPPVPMEH---RD-----------YSGIESAIVKA
WVKVLGLEQININDKFYDLGGDSISAIYLVKEIGKVFPSLIDISDIFTYPSISEMSDYIQSL----------
>tr|A0A0M2GBF3|A0A0M2GBF3_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces variegatus GN=UK15_38285 PE=4 SV=1
-------------------AGHHDKLFRLGWAALPETSARPAAPGSWAVLGSDELRLAEL------------------KAVGAP---------PGAYPDL
AALAEAVGAPVPETVLSRTPERTGAEG-PQP-PDAVHTAAHDALNLAQSWLA-DPRLATARLVVVTRAAHPDSVPDLAGAAVWGLIRSAQTENPDRFV-L
LDLDDREPS------WRALP-AALAAGEPQLALRDGTAHAARLTRVTASPPDTGTGLAARPGGTVLITGGTGALGSLVARHLVTAGVRDLLLTSRRGPAA
DG--AAELAAEL----TGLGARVTVAACDTSDREALAALLAGI--PEEHPLTAVVHAAGVLDDGVIGSLTPERVDRVLRPKVDAAWHLHTLTRDLELSAF
VLFSSAAGVFGGPGQGNYAAANAYLDALAHHRR-AHGLAATSLAWGLWADETMADTIVDIRRMTRSGMTGLSAQEGLALLDLADTLDEALVPTRLDLAP-
----------------------G---GAGAVPPLLRDLVRGRARRT---------------AQEQTDTDGTALRDRLL---G-----VPAQDRARVLLDV
RGQVADVDAVEPDQAFSELGFDSLTAVELRNRLNQVTGLRLTATVVFDHPNPNRLADQLLAD----------
>tr|B2J540|B2J540_NOSP7 Beta-ketoacyl synthase OS=Nostoc punctiforme (strain ATCC 29133 / PCC 73102) GN=Npun_R2081 PE=4 SV=1
-------------------QNSGVLPEQAVMVAQVAKIP---ASQNWLILADQQGIGQQL------------------ANQLRS---------QEDFSRL
LTSQSAI----NKVVHLWGLDAPNADVLVEGIKTATHNGCGSILHLIQAILQ-AEASQLPRLWLVTEAIANQPLPGIAQSPLWGMGKVISLEHPEAWGGM
IDLEPGLASEKASIL-Q-----LESDGEDHIVFRQQQRYVARLVRSQHPE------LKFQADGSYLITGGLGFLGLKLAQWMVEQGAKEIILAGRRGLPP
RQQRKVKAIQAL----EAKGAKVTILVVDVCDLVQMSLALKQVH-TIHSPLRGIIHAAGVTPGYQLQNLDSKTLEAVLYPKTVGTWVLHCLTQEIKLDFF
VCFSSAGSVWGAKGQGDYDAANHFLDTFAHYRR-SIGLPALSVNWALIGSGGMVNAER---WLSRIGIEEFPAEAGFNALGFLLAANVTQVVAKVDWGKF
KA------------------VY----EANKQRRLLLDIEVASEN-----------------EPEEATVKQPEILEKLK---T-----AQECDRHDLLVAL
QSEVAQVHLPDPQQGFFNMGMDSLITLELRNRLAASLNCTLPSTLAFEFPTINDLVAYLSTE----------
>tr|B2J541|B2J541_NOSP7 Beta-ketoacyl synthase OS=Nostoc punctiforme (strain ATCC 29133 / PCC 73102) GN=Npun_R2082 PE=4 SV=1
-------------------SEGRDSLYQIHWQLQENVAS---PPGNWLIFTDGTENGLEL------------------AQQLEQ---------QEHFRQL
LQDI----PNLDGVIHLWGLAEDTTENLLQGLDKAQTLGCASVLHLVQALVQ-SQQQTQPRLWLVTRAIDSNPL-QLSQTTLWGLGRVIAIEHPELNCTR
LDLPLTATEDIQ-IL-L-----FSTDTEDQIAYRQGKRYVARLEQVRAQF------IPVTSESTYLITGGLGALGLEVAQWLAQQGAKHLVLVGRRSPST
D---AQNAIARL----ATAGVEVTIITADITNPQEVAQCLQQIR-SSHPPLRGIIHAAGVLDDGLL-QQSWERFSRVMAPKVAGAWNLHTLTQDLPLDFF
VCFSSIASLIGSVGQSNYAAANAFMDALASYRR-GLGLPGLTINWGPWAETGMAANLREQARLKDQGIVPINPEQGLQVLGELLTQQIPQGVMTIDWSLF
VK------------------QF----SSRTNLKLFEVLAPTSTK---------------------V-NERSQFLNQLE---D-----SPPNTRQQLLATV
RSQIAQIEKVEPRQRLFDLGVDSLMAIELKNRLESSLGCSLRTTLLFDYPTLEALVDYLSRE----------
>tr|B2J539|B2J539_NOSP7 Beta-ketoacyl synthase OS=Nostoc punctiforme (strain ATCC 29133 / PCC 73102) GN=Npun_R2080 PE=4 SV=1
-------------------AETGNWLYQVHWQPQQLSIL---PSGSWLLFAHDYEQGLQL------------------AQQLRD---------REDFQQL
LEDS-LSQPPLRGVVYL--EASAIPEDVLNALREAQTVSYASALHLVQAVVQ-TPGLEAPRFWIVTRAVSKNPL-QVSQAALWGLGRVINHEHPELSCTC
VDLAANAEADME-IL-L-----SSPDSENQISYHQGVRHVARLERYRGRS------FKVAKDGSYLITGGLGALGLESAEWLVEQGAQHLILVGRNQPSA
T---AQDTITQL----ENAGAQVLVVTADISDAAAATGVFEFIR-SSLPPLRGVIHSAGVVDDGAR-QLSWERFNRVLEPKVAGAWNLHCLTQDLTLDFF
VCYSSIASLIGTPGQGSYAVANAFMDALVCDRQ-AHGLPGLSINWGPWAEVGMAARLRSQSKIVAQGISGITSEKGFQVLGELLGQAAYQGVLPINWNQF
FE------------------QS----SFGIDEKFFEAFTPKLEQ---------------------PEAEEFDVLQQLK---A-----APINEQRALLTTV
CNQVAKVSQINPQQGFFDLGMDSLTSVELKQRLQKSLGCQIPDTFVFNYPTIEAAVNYIAEK----------
>tr|M9QX45|M9QX45_9ACTN Modular PKS OS=Micromonospora sp. CMS I2-32 GN=mmlE PE=4 SV=1
-------------------GGVADALFDLTWQEIGTPTTPTTNWTRHPAAP--------------------------------P---------TGTGSDL
TPVAAEVAVPGTADLLLTG-------D-LAG-PEAVHDEVNRVLGLVQQWLT-GPD--THRLVVLTRGA--D-VTDLAGAAVWGLLRSAQAENPDRLL-L
LDTDTDPA-GD---VTSALALA-LAAGEPQVRVRDGVVSVPRLTRQLVEPST---DAPLFGPGTVLVTGATGALGTAVARHLVATGVTRLLLVSRRGPAA
QG--ADDLVAEL----TAAGAQVELVAADVADRAQVAALLD-----ARADLSAVVHTAGVLDDGVVSALSTARLSAVLRPKVDAAWLLDEATRGRDLSAF
VLFSSLSGVLGAPGQGNYAAANAFLDALAVSRR-AAGLPAVSLAWGLWGEGSMTDRLADRERMSRGGVLPLATADGLALLDAAVGAAYPTVPARLDLAAL
R-------------------TLG---ED--LPLPFHGLVRPARR-T---------------A-ARAAAGATGWAADLA---A-----LSTDDRERAATAV
LSQVAAVERIDAGRAFQELGFDSLTAVELRNGLSAATGLRLPATLIFDYPSPRDLARHLLSE----------
>tr|M5TNB2|M5TNB2_9PLAN Polyketide synthase type I OS=Rhodopirellula sp. SWK7 GN=RRSWK_00722 PE=4 SV=1
-------------------TKPDELLYQTRWHRQALV---SSQSHRWVVFADRIGIAKDI------------------A-RVVE---------SDNYEKL
LGSLSGE-DRPTSIIDLWAIGNESENG-NNPAELA-HRECSHALLLLSTLAK-NSSLPIAHTTFVTRAIT-DDV-SPSQAALWGLGRTAMVEMPHLSMTF
LDLDSSQSIESCDEV-QTRLVGEDASSEDHVAFRAGERYVARLEKA-ADLLRVAYPTLSFGNGTVLITGGLGAIGRQVAQYAVTQGATHLAILTRRSSDD
----VKDELASM----QECGASVAVLQGDVSDRESLVAAVRELP-SSYPAIRGVFHAAGVLRDGLQ-TMELDQLDQAMSPKTHGAWNLHDVFD-DQLDFF
VMFSSVAGTIGSPGQANYAAGNAFLDALANYRR-GLGLPATSIAWGPWDAEGMAATPRR--QLAERGMSPLQPSTAMHLLDLAIQNRVTPAVMDVNWNVM
LG------------------KM----VGGGSS-LMSEFRSATASTE---------------KSNSGGARDEKLVARLM---A-----ASAEERLQQLQSV
ASELADVDAIEADQPLASLGLDSLMGMELRSKLESRLGIELPMSALFDDPSVVSLARVAGEA----------
>tr|Q7UJD0|Q7UJD0_RHOBA Polyketide synthase OS=Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1) GN=RB11975 PE=4 SV=1
-------------------ESLDDSLYQIDWQATES---LPASKQVWLLGDP--GSRRDL------------------AKQLIG---------F------
LAEKSES-LPLAALITLWDPSGKS----SNPADDA-VAVCQSALKQIRSAIT-HVPVSKRGWWHVTTPVSESSI-DLVHAPLWGMIRVAMMELADLKPSL
LETDPSASDQSNLVI-A-----IAADDEDHVAYRDGTRHLGRLVKR-RAPAETRMS-EEASESTVLITGGTGAIGLKLAKHLIKDGATSIALLSRRQPVG
D---VAAKIDALK--QDADSVQVTVLQGDVGELDSLRSALKQLP-GSLPPIRHVYHAAGVLQDGLM-DMTEEQLRVPMGSKIQGGWNLHVATKDLPIETF
VLFSSIAACLGSPGQANYAAANGFLDALSEYRR-EKGLPATSIAWGPWAESGMAATESS--QLESRGMRLLPAIACLQTMQQLIDAGDQYAVMDVDWPAM
TK------------------SM----RRSR-P-FFAEFADRSQVDG---------------K-ASVDQVDHEFRAQLS---E-----VPESERTERLRRF
ASELARLEQIDVKQKLSELGMDSLIAMELKNNLEQRLAITIPMSALVESPSINSLVGHVVSQ----------
>tr|M2B3L2|M2B3L2_9PLAN Polyketide synthase Pks2 OS=Rhodopirellula europaea 6C GN=RE6C_02442 PE=4 SV=1
-------------------ESLDDSLYQIDWEATDS---LSDIKQVWLLGES--GSRREL------------------AKQLVD---------F------
LAEKSES-KPLAGLITVWDPSDGS----SNPADDA-EAVCQSALKQIRSAIT-HVPVSKRGWWHVTQSVSESSI-DLVHSPLWGMIRVAMMELADLKPSL
LEVDPSASDQSNQAI-A-----IAADDEDHVAYRDGTRHLGRLVKR-RAPAATRMS-QEASESTVLITGGTGAIGLKLAKQLIDEGTTSIALLSRRQPTG
E---VAAKIDALT--QDVDSVRVTVLQGDVGDLDSLKSALKQLP-GDLPPIGHVYHAAGVLQDGLM-DMTEEQLHVPMGPKVQGGWNLHVATKDLPIESF
VLFSSIAACLGSPGQANYAAANSFLDSLAEYRR-DKGLPATSIAWGPWAESGMAATESS--QLESRGMRLLPANACLQTMQQLIDAGDRYAVMDVDWPAM
TK------------------SM----RRSR-P-FFAEFADRSDVDG---------------K-ASVDQVDHEFRSQLS---G-----VSESERTDRLRQF
ASELARLDQIDVKQKLSELGMDSLIAMELKNNLEQRLAITIPMSALVESPSINSLVDHVVSQ----------
>tr|A0A0J1BJ36|A0A0J1BJ36_9PLAN Malonyl CoA-acyl carrier protein transacylase OS=Rhodopirellula sp. K833 GN=RISK_001326 PE=4 SV=1
-------------------ESLDDSLYQIDWQDAESSPVVPAVQQVWLLGGG--GSLRDV------------------AKQLVG---------L------
LAAREES-KPLAAIITLWDSSEAS----SDPAGDA-EVACQEALTQVRSAIE-HVTPGKRGWWHVTKTVSASNI-DLAHAPVWGMIRVAMMELADLKPRL
LDLDPSATDQSNSAV-M-----VAENEEDHVAYRGGKRYLARLVKR-HAQDGTRMSKDESAASTVLITGGTGAIGLKLAKRLIDEGATSIALLSRRQPTG
E---VAAKIDALT--EESDDANVIVLQGDVGDLESLRSALKQLP-DGMPPIAHVYHAAGVLQDGLM-DMTAEQLLVPMGPKVQGGWNLHLATKDFPIESF
VLFSSIAACLGSPGQANYAAANSFLDALAEYRR-GKGLPATSIAWGPWAESGMAATESS--QLESRGMHLLPAEACLQTMQELIEAGDHYAVMDVDWPAM
TN------------------SM----RRTR-P-FFTEFADSSLADS---------------N-SKVDQVDHEFRARLA---G-----IPEDERTDQLRHF
ASELARLEQIDVTQKLSELGMDSLIAMELKNNLEQRLAITIPMSALVESPSINSLVGHVVSQ----------
>tr|R1HXT6|R1HXT6_9PSEU Beta-ketoacyl synthase OS=Amycolatopsis vancoresmycina DSM 44592 GN=H480_28211 PE=4 SV=1
-------------------A---GSLFEVAWTPLSAPAGLPA--PLWVEVADAEQVT--A------------------FAEDVP---------PGAVAVL
----EAV-----------------SD-------GAVLELTSRVLAVVQAWLA-APDA-DSRLIVVTRAAGG-PVTDPVASAAWGLVRAAQSENPDRIV-L
LDLDSAVAEG----LEAVLG-GVLMTGEPQIAVREGTLSVPRLARAGEQPEP----AVFGPEGTV-LVSGAGALGGLVARHLVERGVRHLVLASRRGLDA
EG--AKDLVADL----TTLGADVSMAACDVSDRDQVAALLAAV--PAEHPLTGVVHTAGVLDDGVIGTLTEDKLARVFAPKVDAVRHLDELTRGMDLGAF
VVYSSASGVLGAAGQGNYAAANAFLDGLMAHRR-AAGLPGLSLAWGLWELATMIAHLVDKARMSRGGVLPITATEGMDLFDAALASGQPQVPVKLDLREV
RA------------------GAK---HGGAIPPLLRGLVRAGRQQA---------------K--AASAGDGELVQRLA---G-----LAAAEQEALLVDV
RERAAAVEGVPAEMAFKDAGFDSLTSVELRNRLREGTGLKLPATLVFDYPTPLVLARHLRAE----------
>tr|Q79ZT0|Q79ZT0_STRAW Modular polyketide synthase OS=Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / 
-------------------VAHQDWMFEIDWVEHTAASAPATAVADWAVLG--------------------------------D---------EGVHSDI
DALRKAVGAATPAHVLSEG-------D-A---AAATRGALAGVLSVVQEWVA-DERFSDARLVVMTREL--DTALDLAHVAVSGLVKSAQTEHPDRLL-L
VDADDSVTNGGTGGVDPALAAALAALDEPQAAVRDGKLYVPRLARITPPEEP---GHAWDPEGTVLLTGATGGLGRSLARHLVAEGARRLLLASRRGPAA
EG--VGELVAAL----SELGAHVDVAACDIADRDALAELLASV--PAEHPLVAVVHAAAALDDGVITALTPGRLDTVLRPKADGALHLHELTRDLNLSAF
VLFSSLAGVLGSAGAAGYAAANAFLDGLARQRR-AAGLPGTSLAWGLWTDNGMGDRIADRNRMGRAGVVPFSPAEGLALFDAALTVDRPVVPVRLDVPGL
R-------------------AMA---RAGMLPAVLRGLVGDTGA-A---------------AGEAAAAGTTALARRLA---G-----IPEADQEKVMLDV
RHQAAAAARIEPTTAFRDIGFDSLTAVELRNRLKAATGLRLKPTLVFDHPNPVAIARLLHKD----------
>tr|D6AAQ7|D6AAQ7_9ACTN Modular polyketide synthase OS=Streptomyces ghanaensis ATCC 14672 GN=SSFG_07827 PE=4 SV=1
-------------------AGGPHFTHRIDWLRRCLPPAQ--TRHVLLAGTSTATDTAP-----------------------------------------
-ALHEALDTSVTDVAWFWQPAAAKMSYA----------LRAELEHNFRALLEAGLADPRPRVWLVTEWLPGDGTEQLAAAALWGFGHVLLNEHPKLKATL
VDVDRDGEGAA---R--LAEWRAQEPDEYQIAYRAGRRHVRRLLAGEGTPAWDTLDLDVRADRTYVVTGGLGGLGLVTARALVDLGARHLALVSRSGRPT
DE--AAD---ILT--ELSRRAEVSLLRADMGSEAEVGELVAQLH-GLPHPVGGIVHAAGAIGSGLS-ALDWPTIEEQLAPKVYGGWLLHEAAASFPLDFF
TVYSSIASVAGGVGQAHYAAAFSFLDGLAHWRS-RRQMPALSVNWGSWGRVGVSARLSYIKEIERSGVRLFSPSWGLRALQRWERPA-AQVVNVFDWPEF
VS------------------RL----PLANA--LFERVAGTREA---------------------TAQDAGTDLADLL---A-----RPRPERLKLIGRV
GERIAAVDEVDPSADLVTLGLDSVMGMDVKSGLEQEFGLNLPASLTFDHPSVLRIAEFIDGQ----------
>tr|A0A0C5FWZ4|A0A0C5FWZ4_9ACTN Beta-ketoacyl synthase OS=Streptomyces cyaneogriseus subsp. noncyanogenus GN=TU94_00870 PE=4 SV=1
-------------------EDGPHFVHRIDWLRRALPAQP--QRHVLLAGTDRAAGGAP-----------------------------------------
-ALHEALDASVTDVAWFWQPGDGQMSYA----------LRAELEHNFRALLGAGLADPRPRVWLVTEWLPGDGGEQVAAGALWGFGHVLLNEHPKLKATC
VDVDGDGEGAA---R--LAEWQAPEAGEYQIAYRAGSRHVRRLLAGDNTPAWVAFGLRVRPDRTYVITGGLGGLGLVTARKLVELGAGRLVLVSRSGRPT
GE--AAG---ILE--ELAGRAEVSVLRADLGSQSDVEELVARLH-ALPHPVGGIVHAAGAIGSELS-ALDWPAIEEQMAPKVYGGWLLHEAAASFPLDFF
TVYSSIAPVAGGVGQAHYAAAFSFLDGLAHFRR-GRKLPALSVNWGSWARVGVSARLSYIREIERSGVRLFSPAWGLRALHRWERPAAAQVVNVFDWPQF
VS------------------RL----PLANA--LFERVAGRQES---------------------AAAGTGADLADLL---A-----RPKPERLKLIGRV
GERVAAVDEVDPAADFVALGLDSVMGMEVKSALESDFGLNLPASLTFDHPSISKITAFVDGR----------
>tr|M5RT53|M5RT53_9PLAN Protein containing Beta-ketoacyl synthase OS=Rhodopirellula maiorica SM1 GN=RMSM_00604 PE=4 SV=1
-------------------MDPQQWIYECEWTAVSIPNPQPSN-------------------------------------AIRH---------F---Q--
-----------TLLPTTWEPSSQQEHWLPHTHDDVEASVCE-LMKFIQSAVR-QPKTPL---SLVL-AFSTGHS-IPASAALAAMARVAANEYPALQIRV
LDVATCDAMS-------VATWLTRQSDETELAYRNNQFLSPRLITSPRSFSKVSPE-HVTADGSYLISGGSGAIAMGVTRRLIQRGATKVVLVARRAATE
Q---VEALINWA----KENGADCRYLQCDCTNQEELRTALRRLP-ESMRPVVGVIHTAGLLDDSLH-EMTSDSVARVLRPKVDGAVALAKATEDQPLRMF
NMLGSVASVFGSPGQANYAAANAALEAFAASRR-NQGLPANVIHWGPWSSAGMADDPLK--NLASRGLRPLRFDAALDLLIDGNPNGPRSVVVDANWHQM
FS------------------SI----PESAVP-SVLRSLHTANGQS---------------QSEVVSAKDDALLMELR---L-----LDHDARCERLEIF
SQQLGKITTFDRSESLGSLGLDSLMAIELKNTIETKLAIVIPISHFMDEPSIATLARIAAEI----------
>tr|A0A0A7AD06|A0A0A7AD06_9CYAN HapB OS=Hapalosiphon welwitschii UTEX B 1830 PE=4 SV=1
-------------------SYAGNVSQQAVILAQAAKLQ---EPGSWLIFADNQGIGQEL------------------SGLLRS---------QKDFQQL
LLEQVACKTSWRGVVYLWSIDTVSADALVADLEVVSQTGCGGVLSLFQSLIS-KEFSPPPTLWLVTKRVSIETLVGVAQSPVWGLGKVIKDEHPEFNCTL
VDLDPQGNNNAQLFA-E-----PKPTSGDHIAFRNGQRYVNRLVRSDKIV------LQLKADATYLITGGLRGIGLLVAQWMVDHGAKHLVLVGRSRPDS
A---ATEILRRL----EEVGTQVVVIQTDVSQEQEVTSLLNQIK-TSMPQLRGIIHSAGVFEDRRV-DHQWQLFAKVFAPKVSGAWNLHTQTQDLPLDFF
VLFSSAASILGPAGLANYAAANAFLDTLADYRR-SLSLPGLSINWGPWSMVGMANAVRGEVQWATKGIKPIESQQALSILENLLPQDAAQGVMQVNWSKF
LQ------------------QF----SRSSYPNFVSEIAQQAEKSI---------------PQKQQKVNSPQLLDQIK---A-----NSKDQSQSLLITL
GEQIAKAGLN-IDEPLNQMGLDSLMVIELRNRLRAELGVDIPITKFLDGLSVVGLTKLASEQ----------
>tr|D7BSN9|D7BSN9_STRBB Putative type I polyketide synthase OS=Streptomyces bingchenggensis (strain BCW-1) GN=nanA2 PE=4 SV=1
-------------------VRGSHGLFAVEWVPPLSAT---AGPATLAVLG------DDP------------------D--LLD---------ADRYPDL
DALFRAVGAPAPDVVIGNDP---------AG-ADTGLATARRMLTLAQEWLA-GSGADGARLALVTRRTGDDERVDPSAAAVWGLMRSAQTEHPGRFL-L
IDTDTDADTD----Q--DALREAVRTDEPQLALRGGRALVPRMARVDAEPE-LDIDPAPDPDGTVLITGGTGTLGGLIAEHLVRSGVRHLLLLSRRGPDA
PG--AEELMARL----TELGARVRVAAVDVGDATALGEAVAGV--DPAHPLTGVVHAAGVVADAMLPSQDDERLVAAWSAKAAAAARLHDATAGLPLGMF
VLFSSFASTLGTAGQANYAAANAYCDALVERRH-AEGLPGVSVSWGLWSAASLTGGLADVARIARQGIVPNSTEQGHDLFDAALGHGRPALALNLDTRAL
A-------------------AQ----PVAALPAPLRALAADAQARP---------------TA-AAAEEPGDWAARLG---A-----LAPAEQRRLLTDV
RRHAATVEAVPADAAFKELGFDSLTAVELRNRVTAATGLRLPATVIFDYPEPVALAERLRTE----------
>tr|Q846X5|Q846X5_STRCM Monensin polyketide synthase module 2 OS=Streptomyces cinnamonensis GN=monAII PE=4 SV=1
-------------------GPGADGLYELRWTPLPEPLPVPAALSGCAVLGELVAEPGPI------------------D--LEG---------CPCYPGV
GAL----NASPPSMILDTT-------------GGDGLALTERVLRVIQDFLA-APSLEQTRLAFVTRDTGSTEAVDPAVAAVWGLVRSAQSENPGRFV-L
LDTDAPLDQASVAPL--DAVRSAVEADEPQVALRGGRLLVPRWARAGEPVE-LDVPAPLDPDGTVLVTGGTGTIGAAVAEHLARTESKHLLIVSRSGPAA
HG--AEELVSRI----AEFGAEATFVAADVSEPDAVAALIEGI--DPAHPLTGVVHAAGVLDNALIGSQTTESLTRVWAAKAAAAQQLHEATRESRLGLF
VMFSSFASTMGTPGQANYSAANAYCDALAALRR-AEGLAGLSVAWGLWEATSLTGTLADRARIDRYGIRPTSAARGCALLAAARAHGRPDLAMDLDARVP
A-------------------AS-----DAPVPAVLRTLAAAGAPRP---------------TAAAAADGATDWSGRLA---G-----LTEEARLELLTEV
CTHAAGVGAVQVDAPFKELGFDSLTAVELRNRIAAATGLKLPAALVFDYPQARVLAAHLAER----------
>tr|I3WY26|I3WY26_9ACTN Laidlomycin polyketide synthase (Module 2) OS=Streptomyces sp. CS684 GN=ladSII PE=4 SV=1
-------------------APGADGLYELRWTPLSPPVADTA-GTGSAVLGDLDL----------------------------G---------VDRYPDL
AALVGATGAAVPDLVFDTL-------------AGDELHVTEQVLALVQDFLS-APRLDRARLVLVTRDADDPEGPDLAGAAVWGLVRSAQSENPGRLV-L
LDADGPLDRDA--VA--DAVRGAGGVDEPQLASRGGRVLVPRWERAARTGE-LDVPAPLDPDGTVLITGGTGTIGAAVAEHLARTESGHLLLVSRSGPAA
EG--APELAARL----GELGAEATFVAADLSEPGAVAELIAGI--DPAHPLTGVVHAAGVLDNALIDSQNPERLARVWQAKAATARRLHEATEEARLGMF
VMFSSFASTLGTPGQANYAAANAYCDALARHRR-ARGLPGLSVAWGLWEAVSLTGTLADRARIDRYGIRPTSAAKGCALLSAARAHGRPDLAMDLDARVP
A-------------------AS-----QETVPVVLRSLAAAGAPRP---------------TAAVGA-DAADWPGRLA---A-----LTGEERLELMTDV
RTHAAGVGAVQVDTRFKELGFDSLTAVELRNRLAAATGLKLPAALVFDYPQARVLAAHLVER----------
>tr|A0A014L9G0|A0A014L9G0_9ACTN Beta-ketoacyl synthase (Fragment) OS=Streptomyces sp. PRh5 GN=Z951_43560 PE=4 SV=1
-------------------GHATDSLFTVEWTPLPLAAGAGE-DGGWAVLG------------------------------------------TGGHPDP
AALVAALDEPVPPVVLLTKPTREGAE---EV-SAEALSTTERALELVRGWLA-EPRLADARLVVVTRAVDGPARVDLAAAAVWGLVRSAQSEHPGRFV-L
LDRDDEPDSGVDGPHTDVAVARAVQMDEPQLALRAGRALVPRLVQAGTGGAGLDVPAPVDPDGTVLITGGTGTLGALVAEHLVRTNIRHLLLVSRGGPDA
PG--AKELVARL----ADLGAEARIEAVDVTDGAAVHDLVADV--DPAHPLTGVVHAAGVLDDAVVTAQTPERLARVWGPKATAAAHLHAATARLRLGMF
VMFSSAAGVLGSPGQANYAAANAYCDALAVHRQ-AMGLPAVSVAWGLWADASMTGHLADLARMSRSGIAAMSGARALGLMDAACWHGAPHAAVQLDLRTL
A-------------------AR----PADTLPALLRTLLDSGTTRR---------------TAATG-APAAGLVTRLR---A-----VPIEEQHRILLTV
RTQAAAVGAVSGDTPFKDLGFDSLTGVELRNRLAAATGLRLPATVVFRHPTPSAIAAELREQ----------
>tr|A0A0Q4PEP2|A0A0Q4PEP2_9BURK Uncharacterized protein (Fragment) OS=Duganella sp. Leaf61 GN=ASF04_26185 PE=4 SV=1
--------------------PLPDWFSTVSWKRAPAMPVERIQRGCWLQYDIAERLAAA---LESAQQTVVRVAFGASFVVAGS-SCTIRSHCEEDYQAL
FAVLGQLPDRVVHLGSL-ALPAASASYQD-FVL-AQQTGMLSLIYLVRNWARAMPDTQLHVVTNDLFDVLGSEVLLPARSTVAAICNSIPQEYPQVACSH
LDLALTPHCAT---DLGQRAALSLRRPERLVALRGAARWQRGFEP-QVAG--AVAAHSFVQGGVYFITGGLGKIGLALARQLCERFHADVVLTTRSAPSA
EDADRLLQVDRCT----LDGGRLRVLQADAADREAMAAALAAAEQEFG-RIDGVIHCAGDVADAIRPTVGEADCLRQFLPKVQGLLFLDELLRDRDVGFC
MAMSSLSAVLGGIGFGVYAASNTYMDTFCHQKH-QQGDPWISVNWDGWNFAQNAED-KFFDMLHENHIPGSEGLAALAQAL--HLGHA------------
------------PQLVCSTTDLATRHRRWI------------------ERAVPA--------T-APAPDADAAGE----TPAVMVLDGGRNATDASLLQI
WRDLFGMAEVGIRDNFFDLGGDSLLLARLLARIRAEFGDAITLAGMFNSPSIEGISDLIGVA----------
>tr|J2WAI1|J2WAI1_9RHIZ Amino acid adenylation enzyme/thioester reductase family protein OS=Rhizobium sp. AP16 GN=PMI03_05101 PE=4 SV=1
--------------------EYELALSPTLWLVDEHRVFDGKGTGCLEAFERMGHGSRIEFVLDDSSVQIVRVTFRSEFVLASALLFGPRWHCFRSLAHL
SLASADIGAFPLHPALLDARRVRENVYDV-TLFADDAGEVPTPTQIVYIVGDSVPHGA-GHPANALLGDLADEQPRAAQAVLLGAVRAAMWEFPNLRCRH
IDLPVGAGSAD---QAALRNALNHSPLAPTVAVRDGAFYEPYFRSLPA----FATAPRFVDGGAYVITGGLGGIGLALATHVATSATAPCFLVSRSGVSH
P---AEASIAALS----ALGAVVTVVQADCGDRDAFAAALADIKSHCG-RIDGAIHAAGVEASGLIQLAESDAWTCVLAPKTIGTDVLIDALRDEQPDFI
LLCSSLAAVLGGLGQADYAAANAYVDASAQAAR-REGLPVVAVNWDAWAEVGMRVA-YDRAHPNQAPIDATEGCRLFDIAL--AHADA------------
------------QIVVHKAQDIETLIRSLA------------------NEPDRA--------------GSRGVAS----SATTAEHVAPRNALERQLAEL
WRELLGGELPGVQDDFFALGGHSLLGAQLISRVRERFPECLTLAEFLDEPTIERMAASLGTV----------
>tr|A0A0A3JL96|A0A0A3JL96_BURPE Amino acid adenylation domain protein OS=Burkholderia pseudomallei ABCPW 111 GN=X946_4838 PE=4 SV=1
--------------------DVCFTLSERHWFVDEHRIFGGHGTGCLEAFVISHGASQPVLVFAGVQRS-LRAVFKQDFVLESRPEYGPRWHCIDAVARL
RLPHRDLPAFALHPALLDAIERAPRTFDV-TLFSNAQARRPAPSQIVYAWRADESRPA-LDATLDGFTHLADAPAACATAATAASLKAVQWEFPDIVCRH
LDVDDDEPSTQ---QALHT-ELGYFDKAATVCLAAGSRETLRFVDAPAPD--TAQGAPLRDGGVYLITGGLGGIGGELARHIAETAPGAKALIGRQRE--
----QAARLRALE----AAGADVLVLRADVADARQMRTAIAELHARFG-QVNGIVHSAGVEASGLIETGAPDAWRRVLAAKVAGTHNLIDLVAADRLDFV
VLCSSLASLVGGLGQADYAAANGYLDAIARHWS-RARIPVVSLNWDAWTETGMAVD-YTERTAHR-GADSVEGRAIFDLAI--RMPGS------------
------------GIAQLAVSKFGFDR-----------------------QPS----------------------N----AQRKTAAAPPSSDVERTLVGL
WRDLLGVDDVGIDDDFFDLGGHSLLATQLISQVRDLYGRCLTLGEFLDAPTISRILRSIDAT----------
>tr|A8KCI9|A8KCI9_9BURK Peptide synthase OS=[Polyangium] brachysporum GN=glbC PE=4 SV=1
--------------------TVSCVLDDRPWFIDEHRIFDGQGTACLEAHATGPGVAGQTLVFPGARRR-VRVVFTQEFALESATDYGPRWRSVSALAQL
ALPTDDLPDFVLHPALLDAIETAPRVYDV-TVFADEQTQRVAPQHVVYTWAGAAAE-----GGGEVFETLARTLAACHAATAVGLLKAVQWEFPDIACRH
IDLEDTEAATQ---ALLHA-ELGSVDPVSSVTLGQGKRETPQYVALPQPV----ESDRLVDGGVYLITGGLGGIGFELARHIATRRRGVKALMSRTGLDG
ASPGRDACVRLLE----EAGAEVLVLQADVADAAQVADAVDRLRQRYG-RVHGVVHAAGVEASGLIETGSPAAWRRVLGAKVDGIDHLRDLIEHDRPDFV
VLCSSLASVVGGLGQADYAAANAYLDAVARHWR-GQGLAAVSVNWDAWSETGMAVA-YAARTAKQ-GATAVQGRLVFDLAL--GLTHP------------
------------QLVVNAA-DFGGAAPRTP------------------ARQA----------------------K----AARVPSSPPTGTDAEQVLTAL
WQELLGVEQIGLEDDFFELGGHSLLATQLISRVRDLYDRCLTLGEFLDQPTLARILRSLEAD----------
>tr|A0A088X784|A0A088X784_9BURK Amino acid adenylation domain protein OS=Burkholderia oklahomensis GN=DM82_4026 PE=4 SV=1
--------------------EVRFTLSERHWFVDEHRIFERNGTGCLEAFVISHGASQPVLVFAGARRS-MRVVFTQDFVLESRGEYGPRWRCIDAVARL
RLPSRDLPAFALHPALLDAIERAPRTFDV-TLFSDAQARRPAPSQIVYAWGAGEARPA-HDAAHDGFAHLADTPAACAAAAMAGSLKAVQWEFPDIVCRH
VDVDDDEPSTQ---QALLA-ELGHVDKAPTVCLAAGRRETLRFVDPPVPA----SNGPLRDGGVYLITGGLGGIGGELARHIAETTAGAKGLIGRQRD--
----QAARLRELE----AAGADVAVLRADVADARQMQAAIAELHTRFG-PVNGVIHSAGVEASGLIETGTPDAWRRVLAAKVAGTHNLHDVIATDRPDFV
VLCSSLASLVGGLGQADYAAANGYLDAIARHWR-RARILVVSLNWDAWAETGMAVD-YTERMMHR-GADAVEGRAIFDLAI--GMPAA------------
------------GVAQLAVSKFGFDH-----------------------RPA----------------------D----AKRKTAAAPPSNDVERTLVGL
WRDLLGVDDVGIDDDFFDLGGHSLLATQLISQVRDLYGRCLTLGEFLDAPTISRILRSIDAT----------
>tr|B1GYG1|B1GYG1_CHOCO Polyketide synthase OS=Chondromyces crocatus GN=ajuG PE=4 SV=1
-----------------ARHCLDTWSYEIRWEAMARTPPRRPEKGAWLVLADRGGAADQLTR---RGHVALLATSGPREA-LGGGRFHIDPASRADLAWL
LDHARGAGPAVRGVVHLLSLDAPPTEALTETLVAAQQLGCATVQALLDAALP--ISWLITRGAQPAGG--APEPLAVAQAPLWGIGRIAALEHPELWGGL
LDLDPHAPSAIQAEAARVVDELLGPDGEDLLALRGAERRVARLIRSPALPLPAERPG-LRPDATYLITGGLHGLGLEVARWMVEAGARHLVLTGRRGLPD
PTADGAAEIANLER----AGASIRIVAADASNLGQMEALFADIA-RHGPPLAGIVHAAGTSRPALLAQTDQAAVEFLLAPKVQGAWILDHLTRELDLDFL
VLFSSAAAVWGGGLLGPYAAANHFLDAIAHHRR-ALGRTALSINWGSWQAGSMLTHMPEDRYLEGIGFGTMPLDEALEVLGWLLGTPLAQRAIAIDWG--
--------------------RFKPIFEAR-----------------RRR------PLLDLIEAPAANASPAADELLLRRLEADGP-EARMTRLIEHTRRL
VTETLQLAAFDLDQGFFQLGMDSIMSVQIRKRLEADLGRRLPPTLAFDHPSVRRLATYLATE----------
>tr|D0LQX8|D0LQX8_HALO1 6-deoxyerythronolide-B synthase., (Acyl-carrier-protein) S-malonyltransferase OS=Haliangium ochraceum (strain DSM 14365 / JCM 1
----------------------RAPLLRREWRPAERPAASAAAPGPWLLVGGGA-ARARLEA---GGHEVVALDPGELA---------------GDPAAV
ERDSAGGAGAVAGVVHLASLTAEAPAGASSEPVWASALHLVHQGW------R--DAWLVTAGAQRAA---PGGVAALLGAPLLGMARTLAYEHPELRCTR
LDLAADPADGADALAEALVAELLADGGDDEIALRGRRRFVARLGVGAMPAAQLELAGAIRGDASYLLTGGRGGLGLSLARWLFEQGARRLLLAGRSAPSA
A----AEQLAELSR----AGAEVVLATVDVADPAAVAQLLADCE-RPEAPLRGVFHLAGILDDGLIAQQDRARYRRVLAPKIDGAWHLHRLTRERPLDLF
VLYSSVAALLGSPGQTGYAAGNSFMDALSEIRQ-DAGLPALSVAWGPFAEVGLAAAREERERLHDRGMSSMSTQDSEDALGALLARDEPWVGVVLDVG--
--------------------RWLDFYPTL-----------------G-AS----AYFGQLVGD----APGDAQQALRARLEAT-P-APLRAQMQRLVREQ
LARVLQCEAIAAETAFTALGLESLTGLELRNRLEAEVGLRLPATLIWTHGNLASLAGELLAR----------
>tr|A8YP97|A8YP97_STIAU Polyketide synthase AufI OS=Stigmatella aurantiaca GN=aufI PE=4 SV=1
----------------------REQVLRLEWREAERTAGAGAAAGHWILVGQGG-VRERLEA---QGHTVAVIDTHELA---------------SDAVAH
TRESLSRQGSCTAVVHLASLSMAVSSGESSEPVWASALHLTQQGW------R--DAWFVTQGVQSAS---NAGATALAGAPLLGLSRTLSYEQPELRCTR
LDLPAGPSAGVDGLADELTAELLASGADDEIALRGGQRFVARLAFGPLTEVTIEGQGAFRADASYVITGGLGGLGLSLARWMVEQGARRLVLAGRSAPSE
A----ARKLGDLEQ----SGATVVLTAADVAQPAEAERLLREAE-TPNAPLRGVFHLAGILDDGLVTQQDTARFRRVMAPKIDGAWHLHRLTRERPLDFF
VLYSSIASLLGSPGQTSYAAANSFLDALAAHRR-ATGLPGLSLSWGPFSEVGLAAAREVRERLQDRGMASMSTQEGETSLAAILGRDETWVGIVLNVA--
--------------------RWLDFYPTL-----------------S-AS----TFFSGLIGA-SAASVGHTHQALVAKLRAT-P-AQLRIQLEGVVRHQ
LAKVLQCEAIAPQIAFTSLGLESLTGLELRNRLEAETGLRLPATIIWTRGNLSSLARELLDR----------
>tr|G8M270|G8M270_CLOCD Beta-ketoacyl synthase family protein,phosphopantetheine-containing protein OS=Clostridium clariflavum (strain DSM 19732 / NBRC
------------------MFKLKNCFYKYEWVPQRVKYDEHKIEGSVLIFKDELGLAYKLRE---QGMDVIEVNYGNCFQKINDNSYTVDNSYE----SY
Q----VSEISCRKLVKILHMFTVNNGEYD-------EFSSS-----DRAIEK--GIFYMIKGFVNITG--EEKVIIPHNAALLGLSNAIKNEYFKLNCKR
IDVDNE---------------------------------------------EIGENKVFKQQGVYLVTGGTGGIGLEVCKYLSTSKV-NLALINRSNFPD
RKETKQINIMDIEA----QGSKVMIFAVDVSDYNAMKELTDDLR-QRYGRINGVIHGAGVAGEGFLYNKDVKKFSEVILPKIHGTRVLFDLTKEDNLDFF
IMFSSVASLFDLPGQGDYIAANSFLDSFCSYGK-RKGIKTLTINWPAWKETGMAFNTNTN----DTVFKAIHTNHAIDAFEYSLNKDIDRVIIGLDFN--
--------------------FIGLLKEKP--------------------I-----RFSEAIENRSD--DTKAYKSVEINLKGK-G-EESYSIEVN-LSKI
WAEVLGLDEINIYDSFYELGGDSILATRLLQEVEKEYPGILDITDIFSYSSISKMAEYIESK----------
>tr|Q0B307|Q0B307_BURCM Beta-ketoacyl synthase OS=Burkholderia ambifaria (strain ATCC BAA-244 / AMMD) GN=Bamb_5921 PE=4 SV=1
-----------------AEPLP---QLVEHWVERRVEHETAPSIAPRLVLLDEAA-----TA---RSWLAASGE-V------------IDASGLDDAA--
-VLAALGS---EPAVLLAGLPAAPAADQDESWR-MPLLGLVGADRLGDALEA--AGATVRFGLLSADL--DGQGGSPLHGFALGLAKSLSLEWPGRAVTL
LDVDGEGSPDA-------------------------------------LAAPP-LASWPRADGPYLLTGGLGDLAAETCHWLADEGVRHVWLTGRREADA
---AIERQLALREA----TGLRVDYRACDIADRDALAALFADAA-RDG-PLRGIFHCAGVLADGAFATLDDGAFERVARAKVLGSWNLHQLSRGLDLDAF
VLYSSLASLLGSAGQANYAAANGFMDQLARSRR-ALGLPALSLNWPGWGGVGMAARNARG-PG--SGLRRLAPERALGELGRALAGGQAQVGIAVDWS--
--------------------VFGRDWRAS-----------------AAAVP---ALVEDWFAAAAGAVPAEAARELAAAVDVDAR-LEIARHLVGIVR--
--RIMALRPLAQNKSFHELGLDSLMAIELKRALQEGFAARVPATVMFDYPDIDSLAHWLAGP----------
>tr|A0A0D5EGX0|A0A0D5EGX0_9BURK Short chain dehydrogenase family protein OS=Burkholderia ubonensis MSMB22 GN=BW23_5790 PE=4 SV=1
-----------------AEPLP---TLVERWVERAP-AEAAPSAAPCLVLLDDAA-----A-------LAASAD-A------------LDASALDDAA--
-VLDALAG---RPVVLLAGLPAAPADD--EAWR-APLLRFVAASRLGDALEA--AGGTVRFGVLSADL--DG-GGAPLYGYALGLCKTLSLEWPGRAVTL
LDVDAPSSRHA-------------------------------------LAAQPAALPWPRADGPCLLTGGLGDLAAETCRWLAAQGVRHVWLTGRREPDA
---ALARRLALRDA----TGLRVDYRACDVADRDALAAVFAQAA-QHG-PLRGIFHCAGVLADGAFATLDDAAFERVARAKVLGGWNLHQLSRGLDLDAF
VLYSSLASLLGSAGQGNYAAANGFMDQLAHARH-ALGLPALSVNWPGWDGVGMAARSGRR-PGEGSGLRRLAPAQALGELGQALASGRAQVGIAVDWP--
--------------------AFGRDWRAP-----------------A-AAP---ALVEDWLAAPAAARAGEAARELDAA-AGGER-LDVARHLVRIVR--
--RIMALRPLAHDKSFHELGFDSLMAIELKRALQEDF-TRVPSTVMFDYPDIDGLAHWLAGP----------
>tr|A0A0L0L431|A0A0L0L431_9ACTN Polyketide synthase (Fragment) OS=Streptomyces stelliscabiei GN=IQ64_12020 PE=4 SV=1
-----------------ARTAHHEDLYRLEWPTLPQPAATAD-TDVWAVIGAEAP-----------DWA----AHG------------ITRS-ATDLKAL
SEITEGAA---RPTAVLAHVPAAPEGQDRVRHVTGRTLTLV-QDWLADST-F--ADVLVTRGGVPTSA--DGDAPDLTHAAAWGLARSAQTENPGRFVL-
ADLDGTGA--SRDA----L-AAAVASGEPQLALREGRAHIARLARVPA---QAETLDW--RPGTVLITGGTGAIGSVLAHHLVAHGVKRLLLTSRRGPAA
---EGAADLVGLAA----LGAHAEVVACDVADRDALARLLGSLP-EAH-PLTAVVHAAGTIADGVVDAMTPARLDTALRPKVDAAWNLHELTEGMDLSAF
VVFSSIAGIFGGMGQGNYAAANAFLDALAHHRR-ANGLPAASLAWGLWANKGGMSGGLDERI-ARGGIVAFSPAEGAALFDSANATGEPVVLPLLDTG--
--------------------ALAA-QTGT-----------------GGVP----ALLRGLVRP-VGEVAPDAADTLRRTLAGQ-P-EQRRETLLDLVRGH
AATVLGFASVDAERGLLELGFDSLTAVELRNRLGAATGLRLPATLLFDHPTSAAIARQLSVE----------
>tr|V9XQV9|V9XQV9_STRAO Polyketide synthase OS=Streptomyces albogriseolus GN=shaB PE=4 SV=1
-----------------DGMASANSLFLLDWTEVSSVQEAVP-VPVWVPVVSA-----------------------------------------GDVVEL
A----GAG---AGVPAVAVLEAVAAGDGAALGLTSRVLGVV-QAWLGAAG-L--ENVVVTRGAVPAG---DGVVSDPAGSAVWGLVRAAQAENPDRIVL-
VDADPAAAADGRDA----VLAAVTAGDEPQLAVRGAAHFVPRLARATD-RVPDGTPVF--AEGTVLITGGTGSLGALAARHLVSYGVRHLVLAGRRGPDA
---EGAQELAELTE----LGAAVEVVACDVSDRAQVEALLATVP-DAH-PLRGVIHTAGVLDAGVIGTLTPERLARVFAPKVDAVRHLDELTRGLDLDAF
VVYSSVSSVFMGAGSGSYAAANAYLDGLMAARR-AEGLPGLSLAWGLWEQTSGMAANTDDRMSRRGGLQMMTLTEGMDLFHAALGSPRSLLVPALDLR--
--------------------GVRADAAAG-----------------GGVP----HMLRGLVRT-TG---TAQDGELLRRLAGL-P-TADQETLVDLVRGQ
AASVLGHDGVRADTAFKDTGFDSLTSVELRNRLRAATGLKLPATLVFDYPNPQALARHLHTE----------
>tr|Q83WE8|Q83WE8_MICGR Protomycinolide IV synthase 3 OS=Micromonospora griseorubida GN=mycAIII PE=4 SV=1
-----------------ARTPVGELLYRVDWPLLTVGPAQPP-KH-CAVVGDDPY-----------GLAAVLGDQG------------VTCDVHPDVAAF
T--IRSVT---MPDVVVATLPA--STDPDVRDVANRALDLA-QWWLSVATDA--EAVVVTSGAVATQR--GEPLRDPAAAAAWGLLRSAQAEDPGRLVLL
DVAGQRPD--G--A----ALLAALASGKPQLALRDGNLRVPRLTRTETKLVLTMPATI--PGGTVMITGGTGNVGGVLARHLVEVRRGTCRSSSRQGPAA
---PGVDDLAELAD----LGATVTVHAGDVADRAEVERLVAAVP-AEH-PLTAVVHAAGTLDDGMIPSLDQEQVGRVLRPKADGALYLHELTRGSALSAF
VLFSSVAAVLGGPGQGSYAAANGFLDAFAQNRS-AAGLPTVSLSWGLLAGAARMTAHVDQRRMSRGGILPLSGRDLTALFDAALAGTEAHQVPVIDPS--
--------------------AIPDD---------------------AGVS----PLLRGLAAG-AVASEPVDVRSLVERLTGM-P-EEAQQLLENLVRTH
AAAVLGYDAIQGDTAFMEIGVDSLAAVDVRNRLAAATGLRLAASTDFDHPTPVVLAGHLRAQ----------
>tr|U5QGQ1|U5QGQ1_9CYAN Beta-ketoacyl synthase OS=Gloeobacter kilaueensis JS1 GN=GKIL_1822 PE=4 SV=1
-----------------APISGNDSLYGVQWQKVSRAATPS-PTGRWLIAADRTGLACQLRA---AGAECELIFAGDA---SAG--PTIDPA---DPGAF
R--VLSTHPPVDGVIHLWGLEAEAT-------STGQLFGCG-LHWLQALAAS--GTWLVSRGAQS------TETLAVAQTPLWGLGRAMSQEQPEHWGGL
IDLDPAFDPAAA---TALVQELLIPDTERQLVLRGGERYAPRLVRTAL---PATVQPLLPGDATYLIVGGLGGLGIEVAQRLVQRGARYLVLLGRRAPTS
A-------IQELEA----MGAQLLVVQADIADQEQLQELLEKID-LHLPPLRGIVHAAGIVDDGVIEKLDWSRFERVLAAKVSGAWHLHHLTRSYPLDFF
VCFSSMAALLGPRAQASYAAANAFLDGLAQLRH-AEGLPALTINWGPWGEVGMASALPERQRLAEQGLEPIAPAAGLAILEAALTAPGFQLGVLADWQ--
--------------------RFAHQFHDR-----------------AL-W----NFVAGLVPAPD----------------SGTP-AESLERLIALVA--
--RVLKLQRIDQRRPLVDLGLDSLMALELSDQIQAACGVNVPVARFFGRTDIAQLAEQVREE----------
>tr|S0FP06|S0FP06_9FIRM Polyketide synthase like protein OS=[Clostridium] termitidis CT1112 GN=CTER_0310 PE=4 SV=1
--------------------NISQWFYEPVWSQSELQSASKEVRTCYLVFEDSCGLGKETSEYLEKSGHVVSVEQGEQFCHIDERKFMVNPESYSDFDEL
LKKGLPADKSKLQVLHFWTVTGAE-NLSDENLKFHKKIGYDSIISLTQAIGNNGRSADICLVSSNMQCVNGKERIEPGKSTILGPCRVIPKEYGNISCRS
IDIPLTDLVNKHNLVETILTEINNQSDDNIVAYRDGKRWKPYLQDIALKETGSLD-NKIRKNGVYLITGGLGGIGFVLAEHLAKTARAKLILSGRSELPE
LSEHDENKIIKLR-QLEEMGSRVIVISADVTDAEKMRKGISEAESVFG-SVNGIIHAAGIAGGGMIQQKTPQMSEEVFAPKLYGALVLYDIFCRAELDFV
IFCSSLQSLMGDLGQADYCAANAFLDAFAGCWNSKGHNRITSVDWDNWQETGIAADTQVPDNMKRREILSISSREGVEIFERVLIS-------------Q
PQQVIISAQP-------------------LQERIE----------LSKA-----FSQDNFPG--NGTFDEADQAGKVQIK-----GSISKNEIQNKVADI
WKKVLGVKKLGPNDNFFDLGGNSLTGLQLVAEIKREFDIQIAPVVIYEAPTISAMARLL-------------
>tr|K9M8B5|K9M8B5_9ACTN SiaE OS=Streptomyces sp. A7248 PE=4 SV=1
------------------------HVFTQAWEAAEPASVDVLLGRVLVLLPEDGAQEEVRSRLAGHPGDVVFAAPGAAFQRTGGGGFTVGGDLEAGYREL
LRTVAADHGPIDAVAHLWATERTAEGSHLRAFLRALA-------------QEVQQG-ALTVPGRVLIGGDDGQRCEVESW--LGFERSIPLVVPGTSVTI
LAMD---GEAAGRLPGILADELGAE--PVSTLHRNGRRWAQQVRPAELRPVD-AAGDRLRDGGTYLITGGAGGLGAIFGTWLAREYRARLVIVGRRPAED
E--DVRARLAEL----DRAGAAVLYRQADVCDPVALTEAVRT-AVEHFGRIDGVLHAAGVEEHGSIAERDAATFARVRAPKVAGTLALAHADQGGGPDFV
CYFSSSAAVLGDFGSGDYATANRFQVAYAEMLARSEGAGRLAISWPLWRSDGMNFSDAGDFYLKSSGQRYLEPSEGTGLFRLLLAQPGA-AYLALAGERD
RIRGMLRVPPAAPAPASG--------------------------------AVPAPAVDPVVESGHGHPSRAAAGSAGQSA-DEIAADHVADGLRRELNDV
VSQVVPADKLAADENLREFGFDSITLVEFAGMLTESLGVDVTPHVFFSYPTLRTLHEYLLTG----------
>tr|L8PZ43|L8PZ43_BACIU MlnG OS=Bacillus subtilis subsp. inaquosorum KCTC 13429 GN=BSI_21380 PE=4 SV=1
----------------------PPLYYKTEWIESNIPNTKNDLPGLVLIFAENDWQIKELSDSLVDCN-LLFVCRGEKFSINNRNVLTINPAKKADYIKL
FKYIQDQFMLPENILHLWSDSQDNI--SQEGIEKQLESGIFSLLYITQALIEMKNTVKLKFQTEHKAQLP-------LHHALGAFVKTVHQEYPNFHYQI
INVNHAQDM-GVDNYSDIYRKEGDQTSQFEVRYENGSRFTKRYKSANIDGL----SQPLKRKGCYLITGGLGGLGYIIAKYLTEKWKANLILTGRS---S
LTAEQSRKINDLRS----SGSHIEYIQSDISKKDETERVFTFVKDQFG-HLNGVFHIAGVLRDSFILRKTKEEIDQVTAAKVYGTVWLANEIKKLNLDLF
VLFSSTSSIFGSIGQGDYAFANAFLDQYAAVIS-AKAQKTVSVNWPLWAAGGMNIDYEGQLMRRELGLEPLDESTGLRALEDSLCQT------------S
EQLIAVKG----QKEKI---ENA----L---NRAINSLLEQRDE-------------------K---------NERNDELKQEI---------IHYLKKL
LSEELSASFIDEKQYLEKYGIDSIMIMRLTKKLEQNIG-KLSKTLFFEYHSITELADYFLNH----------
>tr|S0ADM1|S0ADM1_SERPL Polyketide synthase PksJ OS=Serratia plymuthica 4Rx13 GN=pksJ1 PE=4 SV=1
----------------------------LQGFSVRAP--EPTPPGNGTLLLVPTWSRKQVRGDVVAPH-ATLFCGEPSVA---------------K----
------AMGLTNDLIFPAMDSEEHI-------ALDFQQQALALFGRVKSLLDGRQPMLLQ-AVVGALPAP-------FSAALCGVLKTARLENGRFIGQL
IELEATARA-DEI---DRLRESSLVPEDIHIRYGGEGRQVLSWREVHSGAV----RIPWKERGVYLITGGAGGLGLIFATEIARQTRSRLILTGRT---S
MNDRIQAAVSQLIA----LGAQVDYCQLDVCDRPGVEALTASTMAKYG-AINGVLHCAGVLRDSYILKKSPEDFLAVLAPKVQGTVNLDLALAQHPLDFF
ILFSSTAAALGNPGQADYVTANSFMDAYAHYRQRAQMGRSLTINWPLWKEGGMAVDDASTLMYQNTGMIAMSAAAGLQAFYQALERE------------E
NQVLVIAG----DIEKL---RLT----L---ANG-GELEEAVQQLLIREVSA----LLDVAATEIDLDLTGFANVDIPALHEAV---------QSLLMQE
ISALLDAADIDNDIELSELGFDSILTTSFANKLNRQYALELLPTVFFEYPTVAGLTHYLAER----------
>tr|A0A0G8ED53|A0A0G8ED53_BACCE Malonyl CoA-acyl carrier protein transacylase OS=Bacillus cereus GN=B4080_3392 PE=4 SV=1
--------------------NIAEWFYTPGWMEKEIVDVTKESTKSWLLFLDHIGLALK-EKLERDGHRVITVGVGPSYKKISLNEFTICPTEQEDYYQL
FNELQKQECLPEEIVHLWNVDNK--DLGI----KTLDTGFYSLISLAKTISKFNYPININVMTNNMQKVVGDESIIAEKSTLLAPIKVFPQEYPNIRCRS
VDFMLS--DNEEALISNLYSEIQMDIIDTVIAIRNNTRYIRIYEPIPDEKVSASKILNIRSEGVYLITGGMGGVGLKLAEYLARTVKAKLILVSRTALPD
REEWDQIRINHIQK-LESLGAKVMTAVADVADEEQMRNVIHQAEADFG-HINGVIHAAGVLRVKPMEKISRIECEEQFLPKVHGVLVLDKLLSNYDDFCY
LVS-SLSPILGGLGFVAYSAANLYLDSFSDKVSNTSNNRWTSINWGDWQYTGSE---QVNKIFNAQSIEALE------------MT--------------
------SE-EGQKTFQCVLGLSG----------LNQVIIS------SGDLNKRF---DQWINL----NS----RKRISELEIQGDKFRNQDEVEEVIIGI
WKEFYSVDTVNVNENFFDLGATSLHIIQIHERLINRLEKHISIGVMFEYPSIRSLAKYLSG-----------
>tr|U4R156|U4R156_9FIRM Thioester reductase OS=[Clostridium] papyrosolvens C7 GN=L323_09740 PE=4 SV=1
---------------------VGEWFFIPIWRRGNLSYGSKKTFKNILVFIDQTDFGNNLAGSLESAGKQLTFKSGASFCQDIESGYFINPDISDDYKNL
FRELYKSQNIPDTILYLWTLTE--DNLHESKVNTAVDMGFYGLIYIAQAIGELNIPISINVVT-NSMHMSGEENINPEKAVIAGPIRTIPKEYTNIKCTG
IDIVVP----QEDKAKCLLAEMAATDNEPLVAYRGNYRWRQSFDEIQLNEC---KGVPWRENGVYVITGGLGGIGLAISEYLAGAVRARLVLIGRTEIP-
--PRENDYINSTEKELEELGTEVLPINADVSDNYRMSKAMSVIHERFG-EVNGVIHSAGLPDGGLIQLRNRETTDSIMSSKIQGTLEINKFIEHNKDFMI
-YCSSLSSIIAPFGQIGYCSANNFQDAFSQHQCNKGHTYTASINWDTWKQTGMAVNLACAHSS-DNLENGMLISEGIEVFKRILN------------SNL
PNHLLA--QV-------LISPYP---LEAYLKRIWD---------MEHEQ---FKIKSE----ESNNPEE----------SLNLQDITSQSDIESKLTDI
LKEILGYPDIGRDDNFFDLGAYSLHLIQLRQRLKAVLNVDISIVSLYANTTISSLSRYLFK-----------
>tr|D2JNV8|D2JNV8_9NOSO Trans-AT hybrid polyketide synthase-NRPS OS=Nostoc sp. 'Peltigera membranacea cyanobiont' PE=4 SV=1
----------------------------------------------------------------------------------------------------
----------------------------------EQESGVLQLFRLLKSLSGYGKSLALTVVTSQSVAVRAFETANPIAASIHGLVATLKSEYPHWRVRL
LDIDRGELPSL----AELFPDNDT-ADFPLLARRDKQWFARKLIPIAFES---NDFPAYKQKGVYVAIGGAGGVGEVWSRHIIENYQAQVIWIGRRE---
LDDKIREKQAKL----AAFGSKPLYIQADAKNKASLEKALDEIR-QSYSCINGVVHTAIELQDQSLAQMSIARFRTGLFAKAETSVRLVQVFQHEPLDFV
LFFSSLISFGESPGQANYAAGCTFLDAYAQQLGKDWAVSVKVMNWGYWGNTGVVADATYRERMRQNGIGSIESQQAMAALNRLLQG--QVVGSAPSQTAH
PVVENVAPEIRYSQQWQLIRTHRTDARDALLQNLLLANSPNGRSLPVTYYHKWLDVEELWQKAYRGNPVADFFNEVIAEVGAGTSVMSLQERTTEFVRQT
LSERTPANKVRLDTPFEQYGVDSIVQVGLIQKLEQVTG-SLPNTILFEYSTTRELVDYLLAHHQE-------
>tr|S5R120|S5R120_9PROT Mixed type I polyketide synthase/non-ribosomal peptide synthetase, PedF-like protein OS=Candidatus Profftella armatura GN=dipT 
----------------------------------------------------------------------------------------------------
-----------------------------------KNNVIIQLFRLIKVLEGYENDLKITIVTIQGLFICDYDEINPHHASIHGLVSSIAQEYPMWSIKA
IDMINNNVINWS--VS-LWYQLLG-VKNISIARRKYNWFFQKLIPLNFY----ISKDIYRKNGIYLVIGGAGGVGSIWSEFMIKNYEAKIIWIGRSP---
KNNILQEKINNIS--IKYNGICPIYIQADARNSNILFSTYQKIK-KDFDHINGIVVSTLSDYDLSFKEMSEDLFINILSTKHDVSLSIEKCFYKERLDFI
IYFSSMISFEKPGGMSAYVSSCTFSDAFSKKINKKWDCVVKTINWGYWNIGGGIISSALKKLIEKRGVESINKEEGMNILKLFLGNITEVLPNNISNIEK
NILNDSLRNLKIPL-----KSKYTEELNYWIIRLLFVKVNCNQAGILDKYIVWWKYTKTWKKRYKNNCICDYFNDVVSEIGAGTSKSVLMNFIQNSILNA
LSEIIQIDIIKLNIPFSDYGIDSILGVNFIQKINNDLKLKLNTTILFDYTTVDSLSQYIITNYKE-------
>tr|Q6VT95|Q6VT95_9BACT Mixed type I polyketide synthase/nonribosomal peptide synthetase OS=symbiont bacterium of Paederus fuscipes GN=pedF PE=4 SV=1
----------------------------------------------------------------------------------------------------
----------------------------------AQRDGVLALFQLVKVLEGYGVEFGMTVITTQALATCDTERIDPTHAAVHGLVGSLAKEYPKWRLRA
LDIDA--RAEWP--VPGLWRLLPH-TRGESRVWRGCEWLRQRLVALNGMPV--AKGRAYRRQGVYVVIGGAGGLGMTWSRMMIRDHQAQIVWLGRSA---
KDATVRAKLDEV----ADDGLAPDYWQIDARDADALRQTFRQVR-ERYGQIHGVIVSTLGDYDQSVAQMSEALFREILSSKLDIGVRLSQCLRDEALDFV
VFFSSMVAFGRSGGMAAYSAACAFNDTFARQLGNELACAVKVINWGYWNLGGGTISAALKRLVEQRGVRPIEAREGLCALAVLLDG--PVKAGTHSCFAN
----VYQPTQPMPQ-----ESPDAARLNLWIVRLLFVQETGRQAGIVDKYERWWRRERLWRECYKNNLICDYFNDVVAEVGAGT-RQDVAARVRELILDS
LAQSIGREQIEQDIPFSDYGIDSILGVGFVQRLNDELGLSLNTTLLFDYTTVQRLAEHIVAEYGH-------
>tr|A0A0B5P0D7|A0A0B5P0D7_BACTU Beta-ketoacyl-acyl-carrier-protein synthase II OS=Bacillus thuringiensis GN=fabF PE=4 SV=1
----------------------ADKSDQPYLVCAPVWKE-EKLVGDTLILSSNLSLYEEWRKRIGSDRNLVFVTPGTKFTELGDLKYTINPSCYEDYEKL
WHSLKRQDVYPDNLIQFYPVVY-----MVQSFIKEMKTRSIRLLYVYENLEDSSYPYY---------------------AGIKSLLKTIVLEHNNFKCSS
VELDSKMTQRCMLELFALAKETSRK--VKEVQWRGNNRYVGNLVEHDIVSSRESLNVGFQKEGVYIISGGLGGIGLLLCKHLLTAYQAKIVVFGRSAL--
-NETKQRALQDVMDN----GGEVIYMCGNVSNKQDVSLIIKETK-QRFGKINGVFHMAGVIRDNYLMKKTESEIQEVIEPKILGSIYLDELTKEEPLDFF
VLFSSISGLLGNIGQCDYAFANNFMDHFVEIREQRRRTNTLSINWPLWEEGGMNVDSEIKQAIKNTGMDALASKDAFTILERGLRSKLNIFTGDLEKIKS
-----------------------------------------------------LFNIQNKSILVSNEKNITLEEMNVSRNDISEENLK--TLTIQLLKEI
ISKEIPIKDIKEKLPMDRYGLDSIIILKVGNELEDYFD-DLSKSIFFQYETIFELCEYLIQN----------
>tr|A0A0K2FAE1|A0A0K2FAE1_9BACL Polyketide synthase OS=Paenibacillus peoriae GN=ABE82_16365 PE=4 SV=1
----------------------DEWTAPETLMLEPVWEE-QAIAQQHLVILCEP----GYISG----EIIESQMNGVQCLILQSEEKSIRTYATQVFEAI
QHILKTESKG----------KT-----LVQLVVP----------------VQDHQQVF---------------------SGLSGLLKTAWLENPVLVGQL
IEMDVEQDPAGMINIL---QENSRGSIEPHIRYQSGRRHVAVWTEIKAS--GEAISIPWKDRGVYLITGGTGSLGLIFAEEITRQRDTALILVGRSPL--
-RGDTKARIEEIEAL----GARVVFRQADVADKRAVEVLIRDIQ-EEFGKLDGIVHSAGMVSDNFIIKKTREELQNVLAPKVTGLVNLDQACKEIPLDFF
ILFSSVAGSLGNIGQADYAAANAFMDAYAKYRSTLVERETISVNWPLWKEGGMRIDGETEK-IMEMGMFAMETGAGIRALYQSLASEKNVLEGHASQLRE
-----------------------------------------------------TLLQQPSLNQAGDASS--MIRESEMGSVIGQDLLA--EKAANYLKQL
LATRLPARQIETDAPMEKYGIDSIMIKQLTRELEKTFG-TLPKTLFFEYQNIRELTQYFLKV----------
>tr|A0A0F6EP06|A0A0F6EP06_PAEPO Polyketide synthase OS=Paenibacillus polymyxa GN=LK13_03570 PE=4 SV=1
----------------------DEWTLSETLMLEPVWEE-QALVRQHLVILCEP----THISG----EMIESQMNGVHCLILQSEEESMRTYAAQVFEQI
QQVLKTQSKH----------KT-----LIQLVIP----------------VQDDRQVF---------------------SGLYGLLQTAQLENPTLVGQL
IEVDMEEDAADIINIL---QENSRNFMSSHIRYQWGRRYAAAWSEIKSS--QEVDRIPWKDKGVYLITGGTGSLGLILAEEMARQKDVALILVGRSML--
-RGHIKARIEEIEAL----GARVVFRQADVDDNRAVEDLVRDIR-EEFGKLDGIIHAAGVTSDNFMIKKTEEELQKVLAPKVTGLTNLDQACKDIPLDFF
ILFSSVAGSLGNIGQADYAAANAFMDAYAGYRNTLVEQKTLSINWPLWKEGGMRIDSETEQ-IMEMGMFAMGTDTGMRALYQSLASGKDVLEGHASQLRE
-----------------------------------------------------TLLQQPSLNQVEDASS--MIMESRKEPGIAQDLLV--EKAANYLKQL
LATRLPARQIEADAPMEKYGIDSIMIRQLTRELEKTFG-TLPKTLFFEYQSIRELTQYFLEV----------
>tr|E3E975|E3E975_PAEPS Polyketide synthase OS=Paenibacillus polymyxa (strain SC2) GN=pksR PE=4 SV=1
----------------------DELTIPETLMLEPVWEE-QAPAQQHLVILCEP----APISG----EMIESQINGVHCLILQSEEESMRTYAAQVFEQI
QHVLKTQSKH----------KT-----LIQLVIP----------------VQDHRQVY---------------------SGLYGLLQTARLENPGLVGQL
IEVDVEEDAAGLINIL---QENSRNSMDTHIRYQWGRRYAAAWTEIQSS--WEAGRIPWKDSGVYLITGGTGSLGLILAEEMARQKDALLILVGRSVL--
-RGHTKARIEEIEAL----GARVVFRQADVADKRAVEDLIRDIQ-EEFGKLDGIVHGAGVTSDNFIIKKTGEELQKVLAPKVTGLINLDQACKDLPLDFF
VLYSSVAGSLGNIGQADYAAANAFMDAYARYRNTLVEQKTLSINWPLWKEGGMRIDREMEQ-IMEMGMFAMKTDTGMRALYQSLASGKDVLEGRANQLRE
-----------------------------------------------------TLLQQPSLNQAEDASS--MIMESRKESGIGQDLLA--EKAANYLKQL
LAARLPARQIEVDAPMEKYGIDSIMIRQLTRELEKTFG-TLPKTLFFEYQSIRELTQYFLEV----------
>tr|A0A0K0PDE8|A0A0K0PDE8_9DELT Malonyl CoA-acyl carrier protein transacylase OS=Candidatus Entotheonella sp. (ex. Theonella swinhoei) PE=4 SV=1
----------------------PESKAIGTWMSFPVWKE-KSWSAQRTVMLIEM----EWVSD----RLIESQIEGTTCVHLTTQANSLQDISVQVFERV
KALMEAKLRG----------SI-----LIQLLVP----------------HSGETLLF---------------------SALAGILRTAHLENPALLGQV
IILEPSETQEGVIDKL---QRDSSCPEDALIRYQQERRQTMAWQELPMSEREQAVQVPWKEGGVYLITGGLGGVGFMFAKHLAQHRSVSLVLTGRSEL--
-DEQRREQLKELEAL----GARVDYLSVDVSLKEAVERLIDYIE-SERGSLTGILHSAGVIQDNFIIRKAVREFQSVLVPKVDGVIHLDQATQALNLDFF
VLFSSLSGINGNAGQVDYACANAFLDAYAHYRNRLVAINTLSVNWPLWKEGGMQIDPQRAEAMFQLGLVAMETSRGIQALIHGLSSGQSVVAGDLERLKV
-----------------------------------------------------AHPSRPSSPPSQ--MD--REHNVIGENELDANALA--SRSIHYFKNL
IASKIPAHRIQNDELLELYGIDSIIIMQLINQLERDFG-PLSKTLFFEYPTIEEVNQYFVDS----------
>tr|A0A0K0PEG6|A0A0K0PEG6_9CYAN Malonyl CoA-acyl carrier protein transacylase OS=Planktothrix paucivesiculata PCC 9631 PE=4 SV=1
----------------------QESKAIGTWMGFPVWQE-KPLSAQHIVMLFEM----EWFSK----QSVESQIEGATCIHLTTKTKTLQEISVQVFEQI
KGVIYEKNKG----------VT-----FIQILIP----------------SSGEMSLF---------------------SALTGLLRTAHLENPAILGQV
ILLEASETQEGLIDKI---QRNSHCPEDTFIRYQQEKRQIISWQELSVS--EQAIPIPWQEGGVYLITGGLGGLGFIFAKHIAQQRKVVLILTGRSTL--
-DERRHKQIKELESL----GARVYYRQVDISQKQETERLIKNIE-NDIGSLKGILHSAGIIRDNFIIRKTASEFQSVLAPKVDGVINLDRATKELTLDFF
ILFSSLAGSIGNVGQVDYACANAFMDAYAHYRNDLVATKTFSINWPLWKDGGMHIDPWTENAMLQSGLVVMETECGIQALIQGLSSGQSVLRGDLERLQI
-----------------------------------------------------LQQTHLSSLPSQ--ID--IGQEGIPENEFGEQELE--ARSLHYFKNL
ISSKIPAHRIQNDELLEVYGINSIVIMQLTNELEQVFG-SLSKTIFFEYPTIEEINQYFVAS----------
>tr|A0A0M9DXX9|A0A0M9DXX9_9DELT Beta-ketoacyl synthase (Fragment) OS=Candidatus Magnetomorum sp. HK-1 GN=MHK_009988 PE=4 SV=1
---------------------------QQVWQQKAIELAETSVHEKILLFSNTLMV-DDIKTFMPN---HIIVNSGDTFEHFSDIHYSIRPDEPEDYQEL
---IRLSGIP-NYIIHDWSSREKFQTDD-ASIQKALAKSFYSLFHLTQTVLTNKLSAPLCIIYVCPMNHPI-------FNSISAFAKTVHQENPMIYCKT
IIIDEE-----TKLSKCLLPEMLTW-DVFDVRYVQNKREIKAIQETKIDENN--LFDSLKKNGVYLITGGSGGIGSILTQILVKNYQARIALCGRKKSLD
Q--AQATQLEQ----LRKNGADIHYFQTNLSVKDDVFSLVQQVNNQFGA-INGVFHCAGMINDSFIIRKNPADIIDVLSPKIFGTLYLDEALDQKNLDFF
VLFSSISAVLGNVGQCDYAFANSFMDHFALYRH------YTSINWPLWENGGMNVDKTIKSEMSHMGILPLSDIGGLNSLLAAIHENKSQLIP-IEGFPQ
KIATMKRSNQ--PQELVVHQKFEIA-----------------------------------ESSHNNI----------------------FQQTQDLLRKV
VSDETHLSKIDIHAPLEKYGIDSIMVVNLTNRLEKIFG-PLSKTLFFEYQSLSELSEYFLSN----------
>tr|B8I8K2|B8I8K2_CLOCE Beta-ketoacyl synthase OS=Clostridium cellulolyticum (strain ATCC 35319 / DSM 5812 / JCM 6584 / H10) GN=Ccel_0863 PE=4 SV=1
------------------------------------------------VMDLGAGIGHEFKRSASNKGHVVLAVPGQSFSEGEGGIYEFEITSPDCFTML
FESLKKKGSVPEKIIIIYPDGQGAL---PDTINESLDRGIYGLFKTIKAIMTQ-KTKAVKLLCVYGGNTTSQN-PCY--AALSGFAKTLFMENPKYTCKV
LEVPDI-----SNVEEKAITELSLNVMEFEVKYSDKCRMVKTIKEI--EKTE-CKSLPIKEDGVYLITGGTGGLGLIFAQYLAEKYKARLVLTGRS---A
LTDEKKVAMTKLEN----CGAKVQYIKADVTSRESVNKLVESVKSSFG-CINGVIHSAGVIRDAFIIKKTLEDMKAVISPKVYGTMWLDEATRSENIDFF
VLFSSASSATGNMGQCDYAFGNSFMDNYAVMRSINPNSVSLSINWPYWKEGGMRLGEETIAMMKKSGIIPLLTDEGIRAFEYGLC-----------CSPA
LSRLIVLK--------------G------EAGRIKNGIKTEKQEE--LKQTIK----EN-------QPAPAVANT--NIAAGEDEKWILKEKTEAFLKEI
LSKQLSVDRIDSVEPLERYGIDSVIIMGLNSELEGHFGK-LSKTLFFEYQSISELAEYFM------------
>tr|C3GUE3|C3GUE3_BACTU Keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase OS=Bacillus thuringiensis serovar pondicheriensis BGSC 4BA1
------------------------------------------------LFDKDEEL---FYELQSKEDKVLLIKPGNTFKHLEDNIFEINPVEEEDYKKL
FQYFKNISINYSNILHLWSFG--LD---DRIVTEQLQHSLYSLFYTNRALVEQ-KMKGIVNVLYF---YPLNN-PLF--EAMSGFHKSIHLENPRIQCKT
IGMNSK-----EDVLPRILNELNCKEIEDEVRYVMGRREIKVLQKF--LPEP-VRNLEINQKGVYLITGGLGGIGFILAKYLAKEYQARLVLTGRS---K
NNNTINSKLKELQS----LGGQVIYLSSDISNENEVKKVIKCAKNHFG-NINGVLHCAGIIRDSLVWRKTEQDIENVIASKVHGTMYIDAATRNENLDFM
VFFSSISGEKGNVGQCDYAFANCFLDNYSRMRRLGRSGKTLSINWPLWKKGGISVDEQTQRFMENLHLVPLEEEQGISILKK--C-----------INTP
EEQVMVLY--------------G------DGEKLNKSQKNEISLE--GERVVL----E-------------VSKK--E----------MHTKVTQDLVRM
VSDIVQKRDILTDVDLDEYGFDSITLTELSNNLNQMLDIHVTPAVFFEISEIT------I------------
>tr|W4BAM4|W4BAM4_9BACL Beta-ketoacyl synthase family protein,phosphopantetheine-containing protein OS=Paenibacillus sp. FSL R5-192 GN=C161_02755 PE=4 
--------------------------HTVRWVEDRGDATAPSSSGTVMIIGNGTELEQELSAGLKGEGRVVHVRPGDQFQQISEDQYEVGGDMPGAYSQL
LNMY---TDEITEIIYMSMMGSSFYPEDLASIEARQKEAFYSPVYLVQALMSFAEEIHLNLIAEYAGHVTGREEITPHNALLMGLGKVIQQEYGHIRSKF
VDVDQS------ICTEDILRERHINGEAYAVSYREGQRYTETFTEIDLNESE---SVPFEPDGVYLVTGGTSGIGLEAARFLASSKPVKLALVGRTLLPA
KEEWQDSRCTKMQGILEALGATVHYYSADLADVVGMTEVIQDITHRYG-NINGVIHGAGIPGDGFLYRKSDDEFQTILGPKVKGTWILEKLTRDQDMDFM
VLFSSGISVIGEIGQGDYTAANCYLDSFAAWRT-GQGRRTLSIDWVSWKETGMSVEFGINGM-----FKTIPTTDGIAAMEAAMSRRLSRVFIGANYGSK
HL--AALGQF---------PFRLSDKLEAGVKRSK-EIADQ----GAQHRPNRTIPQ----EKHTGPVDL---------SG---NEEGRYSETEQQVARI
YSEILGYQEINIYDNFFDLGGNSIMLIRMHERLNEEFPGKVKIAHLFAHTSIHKLALHVNQG----------
>tr|A0A0Q4QSK7|A0A0Q4QSK7_9BACL Uncharacterized protein OS=Paenibacillus sp. Leaf72 GN=ASF12_16670 PE=4 SV=1
--------------------------FAPVWTPEERSS-GADLAGAVLLLGGRSDSHKQIAEGLEAAQAIINVSLGEEYIQHHSGSYTIRNTQ-DDYIRL
FENI---GATLTQIVHMLSLDTIAPIDRVEQLDESQKHGLYSLFYLYKAWLHGKQPLDVVLLTDNAQEVSGVETIRPEHATAIGFGKVVTKEHPPFNVRS
IDMDQD------TDAVQLNEEYGAGSSPYGVAFRANGRYVEQFAQMELDRIA---DEPVTEQGVYIITGGTGGIGLEVAKSLAAASSINLILVNRSAMPE
RERWTDLLISKINAIREAAGAQVKLYQANISDEPELRAMLSDVRSVYG-KIDGIVHSAGVAIDQLLKDKQANVIRDVLLPKVNGTWLLNKCTEDDQLDFF
AMFSSVATIYYGSTQSDYVAANAYMDSFTHYRS-KQGKKTLTINWTTWKETGMAKNSGVATI-----FQTLPTASGIEGFTALLNKQSRRALIGSNYDRL
GI--LLLEKA---------TVRLSEPLQRRLDYHK-QLASA----GSTSNKAAKPKG----AAKSGEVQL---------TG---RDGAAYNETEKTIAAV
CQNALGYAEIDINDNFFELGADSILLMRIHAELDKRYTGLLSVADMFEHSTISKLAEYIVEQ----------
>tr|A0A0B9GZ19|A0A0B9GZ19_9GAMM Uncharacterized protein OS=Photobacterium gaetbulicola GN=RJ45_08770 PE=4 SV=1
--------------------------------------------------GDDKGLAQQLTDLLQAQQHVMRAHSGAAFGQLEPLAYTVRPDSGDDFDAL
FAQLKAAGTMPDTIIHFWQHQSLP----------DQVDVDRLVESQRLALGRAQAQTKLLFVTCHQQAVLEEELVDPFKATLLGASKIIDVEYDGVVSRS
IDFASAPTDESHKQAAHILMRCS--APEPSVAYRYGLRFVPAYGRV------TQEANPLKLGGTYLIAGGLGGMGLAFAQYIADRVPANLVVITRRFP--
--HRHIEVLQQLE----EKGCQLLVASAELDDLDAMAEVISQVHQQFG-RVDGWIHAAGVVDEAGVIQSTPAGLRQGMRAKVRGTLVLDRLLSQDSDFVL
L-CSSLSVVTHQIGQVAYASANEFVDAYATYKQRTSTTAVTAVDWDDWRDAGMSKRSRDKAQLSDELTLT--VAEGQ------EIFAR-ALSCGLE----
--------------------------------RVIISI-----RDL-----------HSWQRTVGGLHPQSIALMTCD-------------ELKSALASL
LKRMLGVSEITPDDDFFRLGGDSLLVIQLVNTIREQFDISLGLEEIMARPALADIEALVLD-----------
>tr|L5MQ59|L5MQ59_9BACL Beta-ketoacyl synthase family protein,phosphopantetheine-containing protein OS=Brevibacillus agri BAB-2500 GN=D478_18964 PE=4 S
-----------------------------------------------------------LVELQAREADVIEVALGAAFEKGG--DRQYKIGSADDFPRL
LQELAHR--DIRHIVHCMGMTEEK-LACADDFHEWENRSVYSFCQLVCELLNYHQEINLYLLGDQAFSVTRREALNPQHAVLFGLAKVVAQEYPQLKCRC
IDLDSA---TAP---STLWAEWEAGEEDFQVAYRENVRYVERLEAQTLQAAEPQ-AVSIRENGVYLVTGGLGDIGLQVAHYLGNKQPVHLCLLARSAFPE
--REQWAEIVREQALAEDSGSSVEVHTVDVADERRLAQTIRQQY---G-AIHGVFHCAGVAGEGLLINKGRAKIAQVLAPKVVGTWLLDRYTEQDRLDFF
VLFSSVTSLLGGLGQADYTAANAYLDAFSDYRQ-AKGRQSVTINWPAWNDTGMAARYRIQ---KEASFCGMHPDKAIGILDAVLRRKL------------
-ARVIVGELNEAHFQTHRYPLFA----------ISPEIRSMF------ARPVAWEPET-----ADATPLAPMLTGRTDH---------TYSAVETRLAAV
WQKVLGIPEANVYQSFQEAGGNSILATSLVKEIEQLYPGRINIATLFAYPSIAKMAEYLENKPS--------
>tr|W7YFR5|W7YFR5_9BACL Malonyl CoA-acyl carrier protein transacylase OS=Paenibacillus pini JCM 16418 GN=JCM16418_316 PE=4 SV=1
-----------------------------------------------------------IERLRNKGESVVIARFGHHFEQTGA-DSCIVNGSEDDFDQL
LHWIGAG--EISRVIHMASPSNRS-NLSWEQFEQSQAQGTYSLLFLVRSLIHCQQRIDISLIADHVHHVNGDEPLNPEAGALFGLGKVVHTEYDNLRCRA
IDMDAA---TGP---DDILEELYLEREYYNVAFRSGNKYMERFSKAELSDYAEM-PVKVKDEGAYIITGGTGALGLEAAKYLVERGAAHIALVSRAPLPV
--REDWNSLLEGELTAEAKGAVVSCYSANVSDIHAMNQDIRSQY---G-LIYGIVHSAGVAGDGFLINKSLDVFNEVYLPKVYGTWILDHLTQGDPLDFF
ILYSSGASLIGEAGQGDYCAANSYLDAFAAYRS-ARGQRTQTINWVKWRDIGLAVNKGSN---HD-GYKLLATEIAMKALDEILHRDI------------
-TQIMVGQMNLEQYLSMMELFFK----------LAPEIEAVV------KRSVSEQSRI-----LKNISVTIQMSGREGS---------SYSEVEMTLATV
YQEVLGFKEINVFDNFFELGGNSIMLNLMYARLQKLYPGQLKLTDLFTYTSISRLAEYLTNNNN--------
>tr|A0A0N7FMV9|A0A0N7FMV9_VARPD Var4 OS=Variovorax paradoxus GN=var4 PE=4 SV=1
---------------ARRRVPLPAYPFQRYWVEAPRGEKAPQRTEPLAVLGDSRSLTGHLVRQLRAQGTVVLAERGTAFARTAHGHWTLRPGARDDHARL
QTEIAADFGAITGIYHLWSLDEALPA--QQPQAELLERSFFSLLALVQSLDAGDRTLPLAVVANQLEDVTGTEPLCPEKATLRGIGKVIGQEYPRVHCRV
IDVVAPESDAEGRLVAQIVAEAAAAEPEPLVACRGAHRWIKTYEPATLTAAA---QPRLRREGVYLVTGGLGGVGLALAKHLAVQWQARLVLLGRTAPPA
LKARLQ-QLLELEA----LGAQVLTVSADVSDADAVRAALAQADARFG-PLHGVVHAAGDAGGGMMAGRTRAQVDTVFATKVRGTRVLFDALRGQPDFAL
L-CSSISSVAGGLGMSDYAAANAYLDAVAVAHERLGAFPVFSVNWDAWRGLGMAAHMDVPD-----D-------------------------IGMDGP--
-------------------------EGARVFERIVNGITTDLTTRL--------GP------LDNGMLD---------LLGDEAPFVAPQGEVETALAAL
WTERLGIAPIGVDDNLFELGGDSLVAIQLLSRVRKRYATELHPSEFFKAPTIAGLAARL-------------
>tr|C5BJI2|C5BJI2_TERTT Modular polyketide synthase, type I PKS OS=Teredinibacter turnerae (strain ATCC 39867 / T7901) GN=TERTU_2203 PE=4 SV=1
-----------------KQNAQPLLKFEPQWLQVPPAPINDERAGVTLVLCEPFEHADERSFADGTKGPVLWARAGSTFTVEPNVHCVWNTTSDNDYVAL
ANWLREFNRSSTETV---IYVRNGLDNA---------RLGFNLLDLMRAWYKQKQPVNTVFLHSE--------SHYSDACAVASLAKTAALEFPAFRLKS
LEIDTS--LNDISTLQTAWSESH-LDSGVHVRYADGARYEKRMQPCV-PAASVNQLKNFRNGGAYVITGGLGGLGIIFARYLATHYKANLVLVGRRELDR
AATTICDEIAD-------CGGRAIYMSADISETTHVSAVLHKTRESFG-ELHGWIHSAGVIRDALLPFKTRDQISEVLTPKVSATKALHQALRNQTLDFV
LLCSSVSAMLGSKGQADYSAANGFMDGFAEAVS-HPAQPWISVNWPLWKDGGMQIAEKDLDVLQAAGLDVLTTDAGMQTFERAVIGS-TATVLEMPGDL-
---------------AKFITRFE------QVENQFPALAAT-------EEPARAQVAERLELQSINPA-SAATHQKTVVS----EDF------TPQLRAI
LSELLKLDDIVDDEPLDSYGIDSVQTVSLLESIEKAFDIAISVIEFSELNTLQKIADYILGQ----------
>tr|A0A0C5V8V4|A0A0C5V8V4_9GAMM Polyketide synthase modules-related protein OS=Gynuella sunshinyii YC6258 GN=YC6258_03739 PE=4 SV=1
-----------------QQHRQPWLQFASRWCETPLPISASDGEGIILAFVDPADAVIN------NNQNIYRVVPGTTFSTEQ-QLITLDEHQDSHYVAL
VEYLREICKTRQSTI---LYQPRSGPDG---------RHGFCLLDLMRAWYKQKATVTALFLYQA--------DQYADACAVTALAKTAMLELPTFRLKA
LAVSET--ADI---WSNGLREST-SGSGVHVRYDGQRRYEQRTLATV-PTGAH---GAFKHHGSYVISGGLGGLGILFARHLLQHYQARIVLVGRRPDSA
EIQMQCQSLQA-------LGGTVAYMSADVCETADLQRIIATA-RQAG-NLNGWIHCAGVIRDALLPFKQPQQIQEVLAPKVTAVEQLYQALQGQTLDCV
VLCSSVSAMLGSKGQADYAAANGFMDGFAEQVS-SPAQPWISINWPLWREGGMQIADSDIAVIEQAGLAVLDTETGLAMLEHAVSCG-ASQYMAMTGQQ-
---------------EVLTRRLA------MVERQMLPAESA-------HNPPVATMATFAEMAEIGIT-DISIADRGVDS----TVI------QRQLRQL
LSDILKLDDISVDEPFESYGIDSVQTVTLLEQIEARFQLTLSVSEFSDLNTLEKLAGHLAAE----------
>tr|A0A081NVN2|A0A081NVN2_9BACL Uncharacterized protein OS=Paenibacillus sp. MSt1 GN=ET33_22700 PE=4 SV=1
-----------------APSKQGLLYYTSKWREEACGP-----EAKGLLLNG-ESLADW-MRGELGEEVPFRRLTIA------QDPD-R---YLEA----
---LQEVKASGFQILV-PAVRPGG--------------EDLGLLVLAGALIRFKEPIKILYAGESMS-----SEALPALYAAGGLARTLKYEYPRLHLEV
AAFTDR--FENCGLLEELFA-SA-PAPLHEVRYVGGTRQLREMVTVA--GGLQKQAYALRQGGVYLIAGGTGGLGQIFSDYLAKEY-AKVVLLGRREQDE
RIAAQLDRLAS-------LGGSGLYIRADLGDAGQVRAAVEQARATYG-SIHGVLQGSGLIEDSFILRKTTESFEKILQPKLAGTLHLDDATAGDELDFF
VMFSSIAALMPNQGQCDYSSGNSFMDAYAAHRQ-QLVGLSLAINWPLWANGGMTVEPEEKEHWKVFGMQPLETPQGLVLLREALHLG-FAHIVGIEGDQ-
---------------MKINQHFG------IRKKA---------------E--------------------------LDVP----TMI------RRDLYSI
LAQALHLAEIGAGQQLQQLGVASLSLLQIANLISQYFGVDFKPPLLFEHGTSQQILDYLLQD----------
>tr|B8I8K0|B8I8K0_CLOCE Beta-ketoacyl synthase OS=Clostridium cellulolyticum (strain ATCC 35319 / DSM 5812 / JCM 6584 / H10) GN=Ccel_0861 PE=4 SV=1
----------------------------------------------------------------ENGSKVVYSQGKTSFNRDDDKTYTINPKSHEDYQEL
FKSLTQQGKSITNIIHLWD---------LSGKIGTNDTGLYSIMYIFRAVTALKLENRTRCLFTFRDNI----QVCQ--EAVSGFANSITSVNHRFSVQF
DEYTLENV--TIPPVLAVELTSKNVSNGMEISYENGERFIKQISRVEELGA--GDSNILKPQGVYIITGGVGGLGMIFARYLAKKYNARLALTGRSPFNK
DTE---EKLSSL----KGLGGEAIYCRGDIVSTEDTQRIVKEVKDAFG-GIDGIIHSAGLSGEKSVMEVDRNDFEKIMLAKTHGLINLDLTTKDEAD-FI
ALFSSISSIVGDFGGCSYATANSFLDRYAYARSAQVKGITLSIDWPLWGGGGLELPEEMAAL-EYSGMKPINAETGLKAFEDALRS-------------G
CIQLIVAGGD--N--RKVDRALK---------------------VGRGKGAEAASVELQETENKPEGSQESMI----------------LEQAEEYLKGL
LSNTINAERINAKLPLEKYGIDSVMIMEINSLLEKDFDS-LPKTLLFEYSNLHDLAKYFVKN----------
>tr|Q2XNF8|Q2XNF8_LYSLA Nonribosomal peptide synthetase-polyketide synthase hybrid OS=Lysobacter lactamgenus GN=cpbI PE=4 SV=1
---------------------HEDWFYVPMWRLRGAKPGADATLADALVMGDRGGIGERLSALRRAGQRVVVVRPGDAFVRLDQDEYALAPDDEGHYGEL
AAALQRDGLRIDRLVTLWSLDPLA---AAADADAAAGSGSFSLMFAIKALMAHNEGAAIHAVTQDAYRVTAAESPASEQAAIVGLCKVAPQEYPTLRCQH
IDFSRREPDFAASAAASLFAEVAAGRADKFVAFRRAARWTQTYEQQKVAAED--AAPRFRRGGVYVITGALGKVAYALADHL-ASMAAKLVMVVRDDLPP
RSVSPGDPVPKLRLLALECGAQLLVCKADVTDEAQMLEVFEQAEVR-YSRIDGVIHCAGQVRESVLSDIDLAHCREQFLPKVKGAMVLQRVLKHRDVDFC
VLMSSLSAVLGGLGFAAYAGANACLDAFAAARHAQGDERWLSIDWDGWKFPGEGEDA-------AYGV---SAVEGAQALAYALSADLP-----------
---QLVHST----------ADLKTRMDKWV-EKLAQE-------------PA---------------------HMRLYVRGGGAATVAPSNTIEFQLLEI
WQQLLGIQDIGVRDAFFEAGGDSLLATIMVARINKAFGVNLPIRIVFEEETIERIALQIDELTKRP------
>tr|A9ECY5|A9ECY5_9FLAO Keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase OS=Kordia algicida OT-1 GN=KAOT1_04255 PE=4 SV=1
---------------------FTDLYYTHIWEASSVTKNAKDTSKSIVVFDTDEKLFNSYKKDT--KTPVILVQQGKAFQKVSDNQFTINPENKEDFNQL
FTSLQEQGIGLDKICYGWSKDTFKED--EKSLDNALKTGVYAFLYVCQAVMQLKNNISIAYFYHGAENDAQP--H---NAAINGFAKSLHLEQSSI--SC
KTIEILEVEDSSKIAELVIAELQEDTVELAVRYEGEERFVRKLQNIANWRKNNTNKQGIKEKGVYLITGGAGGLGFIFAEYLAKECKARLVLTGR---SK
LSEEKSAKIAILE----ELGAEVLYVASDVSKLKDVKKVIAATKKKF-GAINGILHSAGVLRDSNIRNKTIEEMQAVFAPKIYGAYYLDTLTKDTELDFF
VTFSSMAAVGGNMGQSDYSYANHFMDTYVKRREALKGGKSLSLNWSIWANGGMKLDAQMEAFFNSLGIRPLKSEIGIGTFTRGLFAEETQVV-VVEGMRM
EIAWGIRE---KEEEPQTATGNEASTNVATTDEASGEITGLVRQ---------------------------------------------------DLIQI
VMDFLEEEDVAVDKILLDIGFDSIGLASYANALNEKYGLDITPVLFFEYPSINEITKYLVKD----------
>tr|A0A023BPR4|A0A023BPR4_9FLAO Uncharacterized protein OS=Aquimarina atlantica GN=ATO12_04990 PE=4 SV=1
---------------------YSKLYYSHEWKKSLLEQEKVNESGPILLFSPDEKLQKVYKDRYKKNEDIILIEPGDKFKKLGSHKYKINPQNPADFKKL
FEALNKDI--IKNICFAWPIGDELKDDEEGFIQKSFDNGIYSFLMLCQSLIEQKDNVQLLYLYLGQIGTSQP--H---HEAINGFAKTLQMEHPKL--YC
KILEIQQSKKYDKILDIVLTELHSDNSNMTIRYQEEERYVRKVKEFSLLQDQDDDSFGLKEKGVYIITGGAGGLGLIFAEYLAAQCKARLVLTGR---SK
LSGERQTKLDRLS----EVGAEVMYIPADVSIAKDVENLVKKAKSKF-GKINGIIHSAGVLRDSYVRSKTREEMEAVFAPKVYGTLYLDRITKDEDLDFF
VTFSSLAAVGGNAGQCDYSFANHFMDSFAEKRKLLKGGVTLSLNWSLWADGGMKLDEQTEIFFKNLGIKPLSIKTGLEAFEKGLHTRKAQFV-VLEGVKI
ERAWGIKE---KETPEAVATDSKTSTEVQVDQQADKELFIVVRD---------------------------------------------------ALSKI
VMEMLDPEDISYDKILLDLGFDSIGLTTYANRINELYELDITPVLFFEYPSIKEIATFLSRE----------
>tr|F8TUA6|F8TUA6_9GAMM Keto-hydroxyglutarate-aldolase/polyketide synthase OS=Lysobacter sp. ATCC 53042 PE=4 SV=1
---------------------FEELYYSHEWRAAELGEG--DDGTALWLLDSDEILYAALRAR---GVNAALAVPGEDYADLGGGRFRLNPREREHYARA
LAALAAQGRAPQRIVCHWAKFEAPQD--DAALDAALAHAPYALLALAQALAESKGRVRLCWLHRGG-AALQP--H---NEAVDGFLRSLALEHPKF--DC
KTVALDEAPA-ERVALRVLAELDARAQLPSARYRDGAREIRRLVRV------EAAALAARENPVYVITGGAGGLGLLFAEHFASQGGARLLLTGR---SA
LDPQREAELERLR----ELGAQVIYAAADVSRADEAERVLALARDRY-GRIDGIVHAAGVLRDSFARNKSAQDLDAVFAPKIRGALHLDRFSAGDELDCF
VLFSSLAALGGNTGQCDYAYANHWLDSFAAQRDSLAGGRSLSVNWSLWADGGMKLDAQTELFFKNLGIKPLDAAVGVAALAKALSLGRAQVA-VLEGAKI
EQAWGLNR---EIAVAPLAAPAVVAAPAASNAGQGDALAAEVVK---------------------------------------------------TLSAL
VMDMLGADELDLDGILLDLGFDSIGLTGFANAINERYALDINPVLFFEYPSIRAIAGALTSE----------
>tr|A0A0P9R3Q7|A0A0P9R3Q7_9PSED Non-ribosomal peptide synthetase/polyketide synthetase (Fragment) OS=Pseudomonas syringae pv. helianthi GN=ALO68_04767 PE=4 SV=
-------------------QPMADWFYQRQWLRVRRLGTQTELRGVVVCAHERMEA-AVLDSLQSVYRQVVEVQAGNGYQQLGPSRYELDPLDPLAFSRL
IAALEHNGHTATELDWLHALPLSVGGVVGEQSATAQWACLDTVSALLQAWGASEHKTALRLLSWQACPVNGTV-LRPELAALAGVTEVAPQEYP-IRCHW
LDLPAARLDTQARQLAALLAD--PMSLPRRMAIRDDYLWQPQLQASPLAEPAAV-SNLLPANGTFLVLGGTGGIGRTLCEHLLQSSQRRVVLLSRRSEIA
--Q----S-------LHAHASRIDSVQADIADLARWPGVLEQLRE-RYGQFDGVIHAAGTGAGSLIRQRDARVLSEAMASKTRGMLAVEALIEQMKPGFV
LYCSSMSALFGGAGHLDYAAASAVLDGFTYYRPNNGCVR-LGINWDIWRDIGMAAAAGICDEAHQRHLAGMSAQEGCRIFDAALTAQ------------L
P-QLLISTTE--L----------------NTARQFYP------ARH-GGSDSTVIEAA---------P--------------AFAAET---GLRERLHGC
LCKWLGVSALEENDSFYELGADSLTLLDLIDELQAATGVVFQLSQFSHRVSLLEVLTLVQQA----------
>tr|I1D2G5|I1D2G5_9PSEU Amino acid adenylation enzyme/thioester reductase family protein OS=Saccharomonospora glauca K62 GN=SacglDRAFT_02240 PE=4 SV=1
-------------------TDPADWFSTTTWTRAPRPSVPDTSW--LLVGPDTIA----GELVGARGDRVTEVRWGGSFTDLGADGYLVAPENPEDWERL
VTALR-------------ALPAHITGTLDGDADSGPFRDFHAVLFLLRALARNRITEVSVVAVSGLAVADEPA-LRPERGMLSSLLRVAEQELAELRFRY
LDVGPVEPGERRERLRDHLV---LAGEETCVAYRGLDRWLPGYAGVALPETG---TSLLRSDGCYLVVGGLGRLGSAIARQL---AGCRIGVVRRSALPP
--A----EKWSRIRELREAGCEVVTASADVADEEAFREAVARLEE-RLGHFDGVFHVAGVVSDDRLVDVTPDHVRPHLAAKVHGLAVLDRVLSDRKRDFV
LVSSSLSSVLGGAGLAAYAAAARYAELFALRRSTGDTPW-LALTWDAWRDTGRLGL---------------DDAEAAEVVRRVLTGD------------P
PAHLVISTAD--L----------------SARIAETA------SERDGEKPGPEVPET----------VYP--------RPDLATEYLAPNDVERRICAL
WQGLLGIDRVGVRDNFFELGGHSLLAVRLVSALQAEFPDATSLATVLKATTVELLAGKLGAA----------
>tr|A0A0N0L001|A0A0N0L001_9PSED Thioester reductase OS=Pseudomonas sp. RIT-PI-o GN=AEQ63_06775 PE=4 SV=1
-------------------QPLADWFHQRQWVRTRRLSAAAGSREVILCSHDAPES-TLLASLNAVYRRVIQVRTGNGFKRLSTDRFELDPLDAEALSRL
LAEVA--EPALGELDWLHALPLAVSGAVNEQSDLAQWACLDTISALMQAWGQTPRTTRLRLMSWQACPVDGEV-QRPELAALAGVTEVVPQEYP-VRCHW
LDWPSSRLGTYAGELAALLVD--PVSLPRRMAVRDGYLWQPRLMPQPLTGPATT-SGLLPEDGTFLVLGGSGGIGRTLCEHLLQAPARRVVLLSRQGQLP
--A----S-------LAAYALRIDCIKADIADLPRWPQVLDQLAV-RYGRVSGVIHAAGVGAGSLIRHRDARQMAQAMAAKTRGMLAVEALIEHLTPDFV
LYCSSMSALFGGAGHLDYAAASGVLDGFTHYRPNDACLR-LEINWDIWRDIGMATTSNSADTAHLEHLKGLSAEEGCRVFDLAMATQ------------L
P-QLLISTTG--I----------------DTARRFYP------VRH-GAVAAVL--------------------------------EAPKVDLSTRLREC
LCKWLGVAELEDDDSLYDLGADSLTLLDLIDELQAATGEVFQLSQFSHKVSLSEVLGLVSTA----------
>tr|A0A0M8SJM8|A0A0M8SJM8_9ACTN Peptide synthetase OS=Streptomyces sp. WM6378 GN=ADK54_27970 PE=4 SV=1
-------------------LPEDAWLHQPHWVRRRRAVPEPGTPGLVVVAAGPLAA-EALRGLNTGGGRVVRVEAAGAFARLADDRFGVDPTDPVSLRRL
LDALP---AGGERIDWLHALPLAVDGEVGADTERARRACLDAPAALLQALAGFPGADRVRWLSHQAQPVEMDV-RRPELGLLAGACEVGSQEYG-VDCHW
LDLPNGDLAEWAALLVAVLAD--RVALPRRLALRQGYWWQQALLGVTATETS---PAPLAAHGVHLVLGGTGGIGAGIAAWLLSQSDARVVLLARRPRLP
--A----D-------LAPWADRVELIAADLAEEDTR-TILARIDR-LGHRIDGVVHAAGVPGGGLIGGRDGAAMRAATAAKLGGALLVERLIARHRPRFA
AYCSSMSALFGGVGQFDYAAANGLLDGFARHRGDESTVR-IGIGWDIWNEVGMARGALATDRRHQAHLAGLTLKEGQRLFARALRLQ------------L
P-QLLISTTA--V----------------EEARAFYE------APA-DEAPGA---------------T-------------------A--SIAELLADW
LREWLGLDDLDPEVSLYDYGADSLTMLDLIAKVKRHCGIDLELSQLTHEASLSEILGLLD------------
>tr|F3NHF8|F3NHF8_9ACTN Putative NRPS OS=Streptomyces griseoaurantiacus M045 GN=SGM_2572 PE=4 SV=1
-------------------LPEERWLHQPHWVRLRRAGTATDPA--VLVTDDPAGP-ARARELRALRPRVVLVTAGETFARLDEDSYRVDPADPEALGQL
LDVLD----GLGTVDWLHALPLGVDGPVDEERRRARRACLDAPAALVRAAAGR-TGIVPRWLSYRARPVDGPV-DRPELALLTGVTEVAPQEGA-APGLW
VDLPAADLAAVPPLASLLA-S--GEELPTHLALRRGYWWRRDTAPVTAPATAAD-TVPAGPDTVHLVLGGTGGIGATLAGWLLERTAGRVLLLSRHPALP
--E----P-------LTARADRIDLVTADLTAATPD-ALAALVAE-RTGRLDTVVHAAGEGTGGLLARRDPATAHAGSLAKLNGALLVERLIERFRPRTA
LYCSSMAGTLGGVGQYDYAAAAGVLDAFAHHEPEGDTLR-LSLAWDVWREVGMALRVPSADARHRAHLAGLTVPEGRRTLERALSAG------------L
P-HVLVSTTE--P----------------QASRAFYA------GPA-PVPAAT-APAT---------PAATVP----ADAATSASAAVPGGEAAALVGGW
LREWLGLDTLAPDTPLYDLGADSLTLLELIDRIKRHFDVELDLAELSPDVTLTEVLTLLDRS----------
>tr|S3ZEQ5|S3ZEQ5_9ACTN Putative Dimodular nonribosomal peptide synthase OS=Streptomyces aurantiacus JA 4570 GN=STRAU_5766 PE=4 SV=1
-------------------LPEADWLHQPHWVRLSRARTSPHTP-GVAMTATPLSP-EALRVLEARYERVVRVGAAAAFARLAEDVYEVDPADPDSLRQL
LGALA---AGRAGIDWLHALPLAVAGPVGERSDHARWACLDTPAALMRAADVLPPSVRLRWLSYGAQPVEGEV-RRPELGLLAGAAEVVPQECA-VDGHW
LDLPTGEPVDWAAALVGLLAA--SAALPRRLALRQGFWWRQALLPVPAPEVMEP-GGVADEPGTHVILGGTGGIGCALAAWLLAQSDCRVVLLARRPRLP
--A----D-------LAQWTDRVELIEADLSAEPPE-EILSRIER-HTGRVDGVVHAAGEAGGALITRRDGAAMRRAMAAKVRGALLTELLIERFRPDFA
AYCSSMSALFGGIGQFDYAAAGGLLDAFARHRAGETTAR-IGIGWDIWSEVGMARDALRSDARHQAHLAGLAEKEGQRLFARALRLQ------------L
P-HLLVSTTD--I----------------ERARAFYT------APA-GPAQGPSGTSQ----------DE----------HG-----ATPAAVASRLTGV
LCGLLGLDELDPEASLYDHGADSLTLLDLIATVEEHFGVALDLSRLSHQVSVREVVAHIRDA----------
>tr|A0A0L8P847|A0A0L8P847_STRAU Peptide synthetase OS=Streptomyces aureofaciens GN=ADK78_26855 PE=4 SV=1
-------------------LPETDWLHQPHWVRLSRAVPAPRTPGGVVMTAEPLPP-ESLRLFEAGWSRVVRVGAADAYARPADDVYEVDPADPASLRQL
LDALG---PGETVIDWLHALPLAVDGPVDEDATRARWACLDTPAALLQAVAGTPLAEKVRWLSYGAQPVEGPV-LRPELGLLAGVCEVAPQECA-VDGRW
LDLPSRELADCAHQLAALPGN--SGTLPRRLALRQGYWWQQALLPVPTPAT-AP-SVLPDEAGTYLILGGTGGIGSSIAAWLLERSDCRVILLSRQPRVP
--A----E-------LTAWADRVELVEADLAETPTE-TVLTRIEA-VAHRIDGVVHAAGTAAGGLVTRRDAPAMRQATAAKLHGALLAERLIERHRPAFA
AYCSSMAAQFGGIGQFDYAAANGLLDGFARHRAGEATLR-IGIDWDIWSEVGMARDALRTDARHQAHLAGLAVKEGRQLFARALELQ------------L
P-QLLVSTTP--I----------------EEARAFYA------APA-DASVSPVTPGT----------A------------T-----ASAASASAELTDW
LGRWLGLDELDPDASLYDQGADSLTMLDLIGKVAEHFGVDLELSQLSHQVSLNEVLVKAGAE----------
>tr|A0A0P9WX82|A0A0P9WX82_PSESH Non-ribosomal peptide synthetase/polyketide synthetase OS=Pseudomonas savastanoi pv. phaseolicola GN=ALO55_00969 PE=4 SV=1
-------------------ELMADWFYQRQWQRVRRLGTQPERRDRVVCSHERIDA-ALLGSLQGVYRHVIEVQAGNGYQQLGPNLYELDPLDPLAFSRL
IAELDQSGQVATELDWLHALPLSVGGVVNEQSAAAQWACLDTLSAFLQAWGECAQKTALRLLSWQACPVNGQV-MRPELAALAGITEVAPQEYP-IRCHW
LDLPTAQWGSQALQLASLLAE--PTSLPRRMAIRDGYLWQPQLQPGPLALPKVA-SNLLPVNGTFLVLGGTGGIGRTLCEHLLRSSQRRVVLLSRRGECP
--Q----E-------LGDYAARIDSVQADIADLARWPKVLEQLRE-RYGHFDGVIHAAGTAAGSLIRQRDAYLLSEAMASKTRGMLAVEALIEQMTPGFV
LYCSSMSALFGGAGHLDYAAASAVLDGFAHYRPNNGCVR-LGINWDIWRETGMAAASGIGDEAHQRHLAGMSAQEGCQVFDAAMTAQ------------L
P-QLLISTTD--L----------------NTARQFYP------ARH-SGAGLTLVDTA---------P--------------AVAAET---GLPERLHGC
LCKWLGVSALDPDDSLYELGADSLTLLDLIDELQAATGVVFQLSQFSHKVSLREVLALVQSA----------
>tr|A0A0P7LNS9|A0A0P7LNS9_9PSED Thioester reductase OS=Pseudomonas sp. In5 GN=AL066_08290 PE=4 SV=1
-------------------QPLADWFYQRQWVRVRRLNTVVERRETVICSNETLDT-TLLESLNTVYQRVIHLRAGNGFKRLGTDRFELDPLDAQALSRL
LDELA--EPALGELDWLHALPLSVTGAVNEQSAAAQWAGLDTVSALMQAWGQASRATTLRLMSWQACPVDGEV-IRPELAALAGITEVVPQEYP-VRCHW
LDWPTFRMGA--QELATLLAD--PASLPRRMAIRDGYLWQPRLIASPLPASVPM-ANRLPMDGMFLVLGGTGGIGRTLAEHLLQAPQRRIVVLSRRGELP
--A----A-------LAAYGSRIDCVQADIADLANWPAVLEQLAR-CYGRFAGVIHAAGVGAGSLIRQRDARQLGEAMAAKTRGMLAVEALISTMNPGFV
LYCSSMSALFGGAGHMDYAAASALLDGFAHYRPSSDCVR-LGINWDIWRDIGMATTSGTGDAAHQEHLTGMSAEEGCRVFDLAMTTQ------------L
P-QLLISTTG--I----------------DTARRFYP------VRH-GAVIAPV--------------------------------NVPELDLHSHLHES
LCKWLGVTRLDDDDSLYELGADSLTLLDLIDELQAATGVVFQLSQFSHKVSLQEILALVDAA----------
>tr|A0A0N0ERZ5|A0A0N0ERZ5_9PSED Non-ribosomal peptide synthetase/polyketide synthetase OS=Pseudomonas coronafaciens pv. oryzae GN=AC511_0541 PE=4 SV=1
-------------------QPVADWFHQRQWQRVRRLNQNMLRRDMVVCSQERLDS-TVLGCLSEVYRQVIEVCAGNGYQRLGPDRYELDPLDSSAFSRL
IAELTQRA-PLTELDWLHALPLSVSGAVNEQSAAGQWACLDTVCALLQAWGQTPRTMVLRLLSWQACPVNGDV-QRPELAALAGITEVAPQEYP-IRCHW
LDLPEPRLSLYARPLAALLAD--PALLPRRMAIRDDYLWQTRLQASPLVAPATV-SNLLPVDGTFLLLGGTGGIGRTLGEHLLQSSQRRLVVLSRSGNCP
--D----N-------LLGYRSRIDLIAADIADLARWPAVLDSLRQ-RYGRFDGVIHAAGTGAGSLIRQRDAQTLAASMASKTLGMLAVEELVKQMTPGFV
LYCSSMSALFGGAGHVDYAAASAVLDGFAHYRADDTCVR-LSINWDIWRAIGMAAAEGVGDAAHQQHLAGLTAQEGGQVFDAALGAQ------------L
P-QLLISTTR--L----------------ETARQFYP------LRH-GAASSPT-D---------------------------IKLAGQSTDLRERLQDC
LCKWLGVPSLDEEASLYELGADSLTLLDLIDELQAATGEVLQLSQFSPTVSLREVLMLVQSS----------
>tr|A0A0N8SNE7|A0A0N8SNE7_PSESI Non-ribosomal peptide synthetase/polyketide synthetase OS=Pseudomonas syringae pv. ribicola GN=ALO47_02540 PE=4 SV=1
-------------------QPVADWFYQRQWQRVRRLSSRPQPRELVVCSHEALDD-TLRSCLKNVYRRVVEVTAGNGFQRLATDRFVLDPLDTPALTRL
LDILAGDQSAPLELDWLHALPLSVTGRVNEQSAAAQWACLDTVSALLQGWGQTSRTPALRLVSWQACPVYGEV-KRPELAALAGITEVVPQEYP-VRCHW
LDLNSAQLAARPEALAALLAD--PVVAPRRMAIRDHYLWQPHLQASPVMASTVD-PCLLPQDGVFLVIGGSGGIGRTLCEHLLRNGQRRVVLLSRHGECP
--D----A-------LQAYRSRIDPVQADIANRTVWPQVLEQLER-RYGHFDGVIHAAGVGAGSLIRHRDARTLSEAMAAKTLGMLAVEELIQQMTPKFV
LYCSSMAALFGGAGHLDYAAASGTLDGFTHYHPNSDCVR-LGINWDIWRDIGMATGAGAGDAVHQRHLAGMSAQEGCQVFDVALSAQ------------L
P-QLLISTTS--I----------------EKARQFYP------VRH-GAGSVAAQPVA---------QVS----------ASTAPGKEEQADLRTRLHDC
LCKWLGVTELDEDNSLYELGADSLTLLDLIDELQAATGVVVELSRFSHKVSLREVLALVQTD----------
>tr|M3C7L2|M3C7L2_STRMB Amino acid adenylation protein OS=Streptomyces mobaraensis NBRC 13819 = DSM 40847 GN=H340_13706 PE=4 SV=1
-------------------LPEAEWLRQPHWVRRHHAGTDPRVAGMVVLTDGPLPE-GALRPFEAAFERVAHVRAAASFARVGADRYEADPADPGSLRQL
FDALG---AGADTVDWLHALPLAVEGPVGEEAERARWACLDTPAALLRAAADLPAGTRLRWLSYGAHPVEGPV-TRPELGLLAGASEVVPQECG-VDGRW
LDLPGRDPADWAALPALLAEP--AAELPRRLALRQGYWWRQALLPVPAPAPVAA-PARPVGPGTYLVLGGTGGIGRSVAARLLEHAGCRVVLLARHAELP
--E----E-------LAPWADRVDLLEADLATEAPE-AVLDR----LATRVDGVVHAAGVAAGGLLLRRDAAAARAASAAKLRGALLVERLIERDRPAFA
VYCSSMAAQLGGVGQFDYAAANGLLDGFARYQGDGSTLR-IGVGWDVWSETGMALDALHADARHQAHLAGLTVKEGQRLFADALRLR------------L
P-QLLVSTTD--P----------------EEARVFYA------PPP-GAGRPA---------------TA----------EA-----RPAPAAAERLAEW
LRRSLGVDELDPEASLYDHGADSLTLLDLIGTVEEEYGVELELSRLSHRVSLAEVLAHLAEA----------
>tr|A0A0K9XBZ3|A0A0K9XBZ3_9ACTN Peptide synthetase OS=Streptomyces caatingaensis GN=AC230_19390 PE=4 SV=1
-------------------LPQSAWLHQPHWVRWRHASGTARGAGTVVLTDGPLPS-GALRPFEAVYERVVHVRAAAAFARAGADRYEADPAEPASLRRV
LDALT---AGATGVDWLHALPLAVEGEPDEETERARWACLDTPAALLRAAAGLPAGTRLRWLSYGAQPVEGPV-VRPELGLLAGASEVVPQECG-VEGRW
VDLPGRDPAGWAPLAALLAAA--GGEPPRRLALRQGYWWRQALLPVPAPAP--A-PEHPAGPGTYVVLGGTGGIGRSVAARLLDGPDRRVVLVARRAELP
--E----E-------LEPWAGRVDLLEADLATAAPE-EVLARLAR-VAPRVDGVVHAAGVAAGGLLARRDAAAARHASAAKVRGALLVERLIERHRPAFA
VYCSSMSAQFGGVGQFDYAAANGLLDGFARYGGGGTTLR-VGIDWDVWNETGMALGAPEADARHRAHLAGLTVKEGQRLFADALRLG------------L
P-QLLVCTTE--M----------------EQARVFYA------PRP-GTAPVA---------------AP----------AS-----APAVPAAGRLADW
LCRSLGVDALDPEASLYDLGADSLTLLDLISTVQEEYGVELELSRLSHRVSLSEVLEHLAAA----------
>tr|H2JY53|H2JY53_STRHJ NRPS-PKS protein OS=Streptomyces hygroscopicus subsp. jinggangensis (strain 5008) GN=SHJG_1133 PE=4 SV=1
-------------------LPADRWLHQPLWVRLRRTRAHSGAAARVVVVPPGTGS-GAWRELERHYARVVLVRAGDTFVRRDGTAYEADPADPAQLAAL
LAEVT---ADGAGVDWLHALPLAVRGEVGRRSETARWACLDTVAALCRALADVPDARRPRLLSYGAQPVTGEV-ARPEAGLLTAAVRVPRQELG-LSLRW
ADLPGPEPADWAWCLPDLRDG--AARSEPELALRGGYWWRRTVQAVPVPVAVAS-RPRPGRTGTHLVLGGTGGIGSTIAADLLRRAGNRVVLVGRRPGLP
--A----V-------LAPWADRITRVRADLAEEAPE-PVADRLAPHL-DGLVGIVHAVGIAAGGLLVRRDRAKARPRTAAKLGAALLTERLIAAYRPDHV
VYCSSMSARFGGVGLFDYAAANGLLDAFAHYAPGDRTTR-VSIGWDAWREAGMAWDVSAPDARHKHHLAALTPEEGAAVFGQALELG------------L
P-HLLVNTTP--L----------------SEAGVFYG------PGA-AAPRRRTTPES---------PAPEQANPPAPAPVRTPPTAPVPADPLRDLTAA
TAHLLGLPGVDPDSSLYDLGADSLTLLDLLDEVNRRFGADLDLSRLSHRVTLTEIAGHLRTG----------
>tr|A0A0B5DST0|A0A0B5DST0_9ACTN Peptide synthetase OS=Streptomyces nodosus GN=SNOD_33510 PE=4 SV=1
-------------------LPMAQWLHQPLWARLRRARTGGPARIAHSADSGDSGD-EAWRFLERHYARVVTVRAGAVFTRIDEDRYQADPADPAHLSAL
LTRVT---GATPAVDWLHALPLALHGEPSTDAETGQWACLDTVAALTLAVAALPEGQRPNLLSHQAQPVTGDV-RTPEAGLLAAALEVPRQELG-VSARW
ADLPGPRPADWAAHLPDVLLD--TALTMTATALRDGYWWHRTLQSVPVS--IPE-SAPPSIPGTHLVLGGTGGIGTTLAACLLRQPGNRVVLVARGTDTP
--D----A-------LAAFPDRVTLVSADLATEEPE-TIAARLAPHL-AGLTGIVHAAGTAAGGLLARREPVTARRATAAKLRGALLVELLLAEHDPDYA
LFCSSMAARFGGVGQFDYAAANAFLDAHAHHAPSTRTVR-MSIGWDAWREVGMAQHALGTDSRHQAHLTALTPEEGATLFEQALDLR------------L
P-HLMVNTTD--L----------------AAASLFYE------PAP-RPRTPA---------------A------------D------D--DPTTALTAA
LCGLLGVDTIDPQAALYDLGADSLTLLELLDEVKRLFGTDLDLSRLSHRVSLAEILGHLG------------
>tr|A0A0M8VUG6|A0A0M8VUG6_9ACTN Peptide synthetase OS=Streptomyces sp. AS58 GN=ADL00_10120 PE=4 SV=1
-------------------LPADQWLHQTQWTRLRRARTSTGEGRRVVAAAPDTAL-PSWGFLTRHYARVVTVRAGQTFRSLGDDAYEADLTDSGHLTAL
LDVLA---VAASGIDWLHTLPLALRGDIDESVDTAHWACLDTVAALARTLAGVPQAQRPRLLSHGAQPVTGAV-RTPAAGLLGAAPEVTRQELD-VTLRW
ADLPSPDPADFAAHLPDLLLD--DGLADRATALRDGYWWHPAVQPVTAPAPPPA-ADPSAALGTHLVLGGTGGIGSTLAARLLEHPANRVVLVARGTDVP
--D----A-------LRTHRDRVALVAADLAVDDLA-SVAKRLAPHLTEGLAGIVHAVGTAAGGLLAHRDTAAARRVTAAKLRGAVLVERLVAEHRPDYA
AYCSSMAASYGGVGQFDYAAGNAFLDACAHYAPHQSTAR-LSIGWDAWREVGMAQHALSADARHQDHLEALTPQDGSSVFARALHLR------------L
P-HLLVSTTS--L----------------DQARYFYE------PAR--PHGPA---------------AD----------VG-----AVALDATAELTGV
LLDLLGTDSLDPDAALYDLGADSLTLLELLDEVKRRYGSDVDLSRLSHRVSLAEIVGHLG------------
>tr|D7C4Q8|D7C4Q8_STRBB Amino acid adenylation domain protein OS=Streptomyces bingchenggensis (strain BCW-1) GN=SBI_02988 PE=4 SV=1
-------------------APEDQWLYQTDWVRMRRATRVKSVR--IVVADATSPP-AHWKALDGHGIRVVHVTAGQAYARLAQNRYEVDPADPDSLTRL
LEAVT-AAATGGGVEWLHALPLGVAGTVGEQSDRARHACLDAPSALCQALARLPQALRPRWLSHRAQPVTGPV-QRPELGLLAGALEIPRQELG-LETRW
LDLPSGLASDWAELLSLVLAP--ADTAPRRLALRQGYWWRAVQQPVRPPAQQAR-TILMEGSGTHLVLGGTGGVGSTIATRLLEQSDARVVLLARRPQLP
--P----A-------LARWSDRITVVEADLAQEPLD-NVLARLAP-YLSRLDSIVHAVGTAAGGLLVRRDGDAMRHTTRAKLHGALLMERLIAAHRPGYA
VYCSSMAAVLGGVGQFDYAAANGVLDAFAHHGSDGATVR-IGIGWDVWRDVGMARTALTTDARHQAHLAGLSSAEALRVFSDALQLQ------------L
P-HLMVSTTP--L----------------EETRYFYE------PDR-HELTST---------------SP-----------A-----MSTAVPHGELAEA
VCQLLGVDTLDPDTCLYDLGADSLTLLDLLSEVKRQYGVDIDLSRLSHQVTLNEVLTHLNGG----------
>tr|L7GQ54|L7GQ54_PSESX Amino acid adenylation OS=Pseudomonas syringae BRIP39023 GN=A988_24774 PE=4 SV=1
-------------------QPLADWFYQRQWQRVNRLRINPEGREVVVCSHERLDA-TTLGSLQSVYRHVIEVQAGNGYQQLGLNRYELDPLDPVALGRL
ISALDQSGQTASELDWLHALPLSVGGAVDEQSAAAQWACLDTLSALLQAWGQNAQKTALRLLSWRACPVNGQV-MRPELAALAGITEVAPQEYP-IRCHW
LDLPTAQLSTQAPHLAALLAE--PASLPRRMAIRDGYLWQPQLLASPLAAPTAA-SNLLPANGTFLVLGGTGGIGRTLCEHLLRSGQRRVVLLSRGGGCP
--K----E-------LDAYASRIDSIAADIADLARWPTVLEHLRE-RYGHFDGVIHAAGTGAGSLIRQRDAQVLSEAMASKTRGMLAVEALIEQMTPGFV
LYCSSMSALFGGAGHLDYAAASAVLDGFTHYRAHNGCVR-LGINWDIWRDVGMAAASGVGDDAHQRHLAGMSAQEGCRVFDAAMTAQ------------L
P-QLLISTTD--P----------------ATARQFYP------VRH-SA-GSTLADTA---------P--------------VLTADTAADCLPEHLHDC
LCKWLGVSALQPDASLYELGADSLTLLDLIDELQAATGVVFQLSQFSHKVSLAEVLALVRA-----------
>tr|A0A085WVX3|A0A085WVX3_9DELT Malonyl CoA-acyl carrier protein transacylase OS=Hyalangium minutum GN=DB31_0097 PE=4 SV=1
--------------------------------------------------AHSQGLRRQLRERSGE-APIIRVQPGEGFRCLSPEHYQITPAREEDYRQL
WEALRERGLQPAALFHLWNHEARPLAETVSTELQEQLLGLQSLFLLARTLPGLR--LRERLPVIYAFQGEGEQPQH---SAVAGFARSVALENPKLRVRV
VRFAPRQAEVP-ADWDALLRELQPPEQTEVRIGSAG-RQVRRFAPVAPPASGTSARPLLRPRGVYLLTGGAGGLGLVFARYLAREAQARVALLGRSPLDA
A---RRASLSELEA----MGAEVLYLSADVADPAALQTAVTRVRERFG-ALHGIIHAAGVIEDAMAVNKPLNSFQRVLTPKIQGTLNLDAATREVPLDFL
VLFSSASAVFGSMGQTDYAAGNQFMDAFATLLR-ERGLRTLSLNWPLWREGGMRIQPEVEEMLRNTGLKVLETGRGLTAFSLAQALPGS-----------
--QLMLLEGD--P-------------A--VIHK---RIELATQPVV---RPQRSAPPPPAAPEPAVA--ERAV--------APPTLETLQSHLEQDLSET
CSALLKVSTSDAEADFSDYGVDSLMIMRILDHLEERYTVSLDPSALTEHPSIRSLAKHL-------------
>tr|V6L2E7|V6L2E7_9ACTN Uncharacterized protein (Fragment) OS=Streptomycetaceae bacterium MP113-05 GN=N566_06530 PE=4 SV=1
--------------------------------------------------DRVQAIR-------AH-NAAVLVTPGSGFARLSAEHFTVSPDSLEDHKEL
RAALEGDGLAPSAIVHLWHLDGSDP----------HKTGLLSVYALCQAW-AVG--RRTALPVVHAYHSRGESPPD---ASVGGLARGLRLEQPKLPLST
VRFAAPSADAA-AAAEAVLGETGSPGDLEVRYTSAGVREVRGFAPVAPTPSGTP---LARAGGTYLLSGGTGGIARHVARHMARAAQPNIVLFGRSSEGE
G---QRAFVAELAR----LGARAAYLQADVTRLDDVERLVAEAENRFG-PVTGVIHTAGVVEDGLLINKKPDSVRRVLAPKFDGARNLDLATADRALDYL
VLFSSTSAVLGSIGTTDYTAANAYMDAFTDWLV-ARGERSVAVNWPLWSEGGMRINPAVEAQLETTGLVPLETAHGLAALEAGLAHDGP-----------
--QLAVFEGD--R-------------T--KVER---MLAVIWPQRV---RADGYAPHRPVKTQHDGA--ESGV--------AD---VEMASELEAMIAET
VTGLLPQTASLMSWTFMELGLSSVDVVGLSRRLGEQLCIDLSPTVFFRCTHVPELSAHL-------------
>tr|G7M3G4|G7M3G4_9CLOT Long-chain-fatty-acid--(Acyl-carrier-protein) ligase., 6-deoxyerythronolide-B synthase OS=Clostridium sp. DL-VIII GN=CDLVIII_3725 PE=4 SV=1
---------------------VPEWFYNWNWKPEPHKYADSEIKGNIVIFSDNSEIEDEFEEIFKTNKYVVKV--G-TEYRFDYSKFIINPIAEEDYVKV
FNIIQG---PVGAVIHLWNLNKESFKLEFAFDDKVMHEDIYSVLYIGKALSKL--NIEKTKLLLVTNNGNENKIPHQASAIT--LAQALDQENAFIDSYC
IDVDKKEYESNREIAQILSDEIKHDLSKGIVAIRGGVRFIRELSAIKFNQTS---KIKFNDGETYLITGGASAVGSEIAKVIAKKAKINLILTGREELPL
IEKW-EEELANNTRYLKELGANVIYEAVDVTKIGDMKALVERIADEYGA-IYGVIHAAGTFDSKTLLDKNIKVINKIIEPKLKGGIITDLVTRKEPLKFF
VMSVSCSEKLWSAGVGDYAAANAFLSAYSYYRA-ADNGKTIALNYSLWAGTGMGSDNGALLALKAQGLNPLPAKKAAEAFIRALSVESQVIHI-ID--KI
EISDV-----EKSST-IKMPQVNSRKLKNIKEIVYKVIAKQ------------------LKV--------------------------------------
-----EEDNFDVGKNFLELGLDSLGAVKVMEMLGTSIGMELYPTLIFEYQTPQALAEYIEM-----------
>tr|A0A0Q5T2U9|A0A0Q5T2U9_9BACL Beta-ketoacyl synthase OS=Brevibacillus sp. Leaf182 GN=ASG16_14595 PE=4 SV=1
-----------------------------------------------------------LQEIREHKIDLIEVSSGPAFQKFSDHHYQI--GSKEDYPVL
LKELMNRN--IRNIIHCMSVVDEE-IECAEDLHALENKGVYSFYHLVCEMLSYNQQINLYVIGDHTFSLTKHESLKPHHAVLFGMAKVIPQEYSQLKCRC
IDSDSD------TSPATIWKEICADKEDFQVAYRHNVRYIEHLEEQMLGNSELQ-DVAIKENGVYLVTGGLGDIGLKVAQYLSTKKSVYLCLLGRNVLPP
REASQIDIIRRI----EKNGSSVDVYAVDIANESKLADVLETIRHQHG-AIHGLFHCAGVAGEGLLINKEHAQMKQVLDPKVIGTWLLDRYTERDQLDFF
VMFSSVTSLLGGIGQADYTAANAYLDVFSEYRQ-AKGQRSVTINWPAWNDTGMAAKYRIKKEAS--PFHGIHPDQAIDILDSILARKVPRVIV-------
--GE-------------------------MNEAHFRTISPAIRRMVT--QPVAFETIEDQQI-------VPILKGRNN---------HRYSDIETQLASI
WQKVLGIPEANVYQSFQEAGGNSILATSLVKEIDQLYPGRINIATLFAYPSIAKMAEYLENK----------
>tr|J3AWZ5|J3AWZ5_9BACL Beta-ketoacyl synthase family protein,phosphopantetheine-containing protein OS=Brevibacillus sp. CF112 GN=PMI08_04780 PE=4 SV=1
-----------------------------------------------------------LVELQAREADVIEVAFGAAFEKGGDRQYKI--GSANDFPRL
LQELAHRD--IRHIVHCMGMTEEK-LACADDFHEWENRSVYSFCQLVCELLSYHQEINLYLLGDQAFSVTRREALNPQHAVLFGLAKVVAQEYPQLKCRC
IDLDSA------TAPSTLWAEWEAGEEDFQVAYRENVRYVERLEAQTLQAAEPQ-AVSIRENGVYLVTGGLGDIGLQVAHYLGNKQPVHLCLLARSAFPA
REAGQIGQIRSI----EDSGSSVEVHTVDVADERRLADVLQTIRQQYG-AIHGVFHCAGVAGEGLLINKGRAKIAQVLAPKVVGTWLLDRYTEQDRLDFF
VLFSSVTSLLGGLGQADYTAANAYLDAFSDYRQ-AKGRQSVTINWPAWNDTGMTARYRIQKEAS--PFCGMHPDKAIGILDAVLRRKLARVIV-------
--GE-------------------------LNEAHFQAISPEIRSMFA--RPVAWEPEDATPL-------APMLTGRTD---------HTYSAVETRLAAV
WQKVLGIPEANVYQSFQEQAETPFSRPVSSKKSSSSTPRCSPILRLRKWRNIWKTSRVPTRR----------
>tr|A0A0E4H817|A0A0E4H817_9BACL Beta-ketoacyl synthase family protein,phosphopantetheine-containing protein OS=Paenibacillus riograndensis SBR5 GN=PRIO_1742 PE
-----------------------------------------------------------LRVLRKQEIELIEVTPGARYHQLAANRYSI--GSGEEYSLL
LKELSNRG--IKHVIHCLSLADEK-IAGIEDLHAAENRGVYNLHHLVTALLQYHQELNLFFVADHTFLVNRHEPLNPHHAVLFGMAKVIPQEYPQFKCRC
IDIDSA------TAPATVWKEICSGKGDFQVAYRDNTRYLEHFGERRLEAAEAG-GVSLKENGVYVVTGGLGGIGLAVAQYLSGKQRVHLCLLNRRTLPP
GP-SQSQRIRQI----EANGSDVDLYSVDISAPNELQGVLQAIRTKYG-QINGLFHCAGIAGEGLLINKGKPEIKRVLDAKVTGTWLLDQYTAQDHLDYF
VLFSSVTSLLGGMGQADYTAANAYLDGFSDYRQ-ANNRRSVTINWPAWKEVGMTLKYDIQEGRS--PFLGLTEEQGISILDAVLQRKLSRIIA-------
--GE-------------------------INERYFQAVPPQMISRGT--GPQEKVIA-DEPI-------LPILKGRYD---------HSYNSYEISLAAM
WQKVLGVAEVNVHLPFQETGGNSILATSLVKEIDGVYPGCVNIATLFAYPSIAKMAEYLKQK----------
>tr|A0A089M5F9|A0A089M5F9_9BACL Beta-ketoacyl synthase OS=Paenibacillus graminis GN=PGRAT_08135 PE=4 SV=1
-----------------------------------------------------------LSELRKQEIELIEVTPGTHYHQLAANRYSI--GSGEEYSLL
LKELSNRR--VRNIIHCLSLADEK-IAGIEDLHAAENRGVYNLYHLVTELLQYHQELNLFFVADHTFRVNRHEPLSPHHAVMFGLAKVIPQEYPQFKCRC
IDIDNA------TASAAVWEEICSGSADFQVAYRDNTRYIEHLEERLLGAAEAG-GVSLQENGVYVVTGGLGGIGLAVAHYLSGKQRVHVCLLNRGTSPP
GP-SQIERIRQI----EANGSEVDLYTADISEPDELQGVLQAIRTKYG-QIHGLFHCAGIAGEGLLINKEKPEIKRVLDAKVTGTWLLDQYTAQDNLDYF
VLFSSVTSLLGGMGQADYTAANAYLDVFSDYRQ-ANNRRSVTINWPAWKEVGMTLKYDIQEGLS--PFLGLTEEQGISILDAVLQRKLSRIIV-------
--GQ-------------------------INERHFRVVPPQIISRGT--GPEARATASVPPI-------MPVLKGRNN---------HSYNSYETSLAAM
WQRVLGVAEVNVYLPFQETGGNSILATSLVKEMDDVYPGCVNIATLFAYPSIAQMAEYLEQK----------
>tr|A0A0N8S0P6|A0A0N8S0P6_9PSED Non-ribosomal peptide synthetase/polyketide synthetase OS=Pseudomonas meliae GN=ALO64_00102 PE=4 SV=1
------------------RELMADWFYQRQWQRVRRLGTQPIRRDRLVVCSHERIDAAMLGSLQGVYRHVIEVQAGNGYQQLGPNLYELDPLDPLAFSRL
IAELDQIGATELDWLHALPLSVGGVVNEQS-LAAAQWACLDTLSAFLQAWGEQKTALRLWLLSWQACPVNGQ-VMRPELAALAGITEVAPQEY-PIRCHW
LDLPTAQW---GSQALQLASLLAETSLPRRMAIRDGYLWQPQLQPGPLAL-PKVASNLLPVNGTFLVLGGTGGIGRTLCEHLLRSSQRRVVLLSRRGEQE
LGD-YAAR--------------IDSVQADIADLACWPKVLEQLRER-YGHFDGVIHAAGTGAGSLIRQRDAHLLSEAMASKTRGMLAVEALIEQMTPGFV
LYCSSMSALFGGAGHLDYAAASAVLDGFAHYRPNGNGCVRLGINWDIWRETGMAAASGIGDEAHQRHLAGMSAQEGCQVFDAAMTAQLPQLLI-------
-------------------STTDLNT----ARQFYPARHSGGLT------------------LVDTAPA------------V-AAEA----GLPERLHGC
LCKWLGVSDLDPDDSLYELGADSLTLLDLIDELQAATGVVFQLSQFSHKVSLREVLALVQSAQ---------
>tr|A0A060PU50|A0A060PU50_9NOCA Putative non-ribosomal peptide synthetase/polyketide synthase OS=Nocardia brasiliensis PE=4 SV=1
------------------RLPEGDWLSQPHWVRTRRAGAAPV-NRLLVLVADAPFQPAVVAPFEQTYLRVVQVVPGGEYRRVAPDVFEVDAADSDSLRQV
LDVLAETDCAGIEWLHALPLRVSGPVGPDS-VEHATRACVDTPAALLRVMAEVAQRVRVWWLSAQARPVDGP-VRRPEPNLLAGVCEVGTQET-GVPGSW
IDLPGTDP---VEWAAPLAELLSGASVPKQLALRQGFWWRQQVSPVAAA-------ALPTAAGVHLVLGGTGGIGASAAAWLLDNGAERVVLLARRAQEV
LSP-WADR--------------VEVLIADLVESDL-DGLVRRIGER-VDRLDGVVHAVGVAAGGLIARRDPAAARQWSAAKLRGALLTERLIQLHRPAVA
VYCSSMAAWFGGIGQLDYAAANALLDGFAGYRGGAETTVRVSIGWDVWRETGMALRALPTDPRHRAHLAGLTVAEGQRVFARALGAQLPQLLV-------
-------------------CTTDLDD----ARAFYAAAPTDTAA------------------G------SA---------V-------ALESAQQLLRAE
LCEVLGLDELDRNASLYDLGADSLTMLDLLDTIKQQFGVELELARLSHRVCLDEIVSRLAE-----------
>tr|A0A0N0E3N2|A0A0N0E3N2_9PSED Amino acid adenylation enzyme/thioester reductase family protein OS=Pseudomonas fuscovaginae GN=PF66_03410 PE=4 SV=1
------------------RNALPDWFHQRQWVRLRRLGSGSPRRGTLVVCANEALDGGLLDALGRVYRRVVQVRAGNGLRRLAADRFELDPGDSQALTAL
LAELI--AVEELDWLHALPLSVGGAVNEQS-LAAAQWACLDTPSALLQAWGEGALKLRLWLLSWQACAVNGE-VRRPELGALAGVCEVAPQEY-PLRVHW
LDLPGSQW---ADQAGTLAALLGDAALPRRLAIRGDYLWQPRLIASPAPA-SLPASPLLPATGTFLVLGGNGGIGSSLCEHLLQAPGRRVIVLSRRGEQN
LRD-YGDR--------------VEVVQADIADLARWPSVVEQLARR-YGELVGVIHAAGIGAGSLIRHRDARQMDSAMAAKTLGMLAVEMLITRLSPGFV
LYCSSMSALLGGAGHLDYAAASGVMDGFAHYQPEASRCVRLGINWDIWRERGMATAVSAGDEAHQRHLAGLSVEEGAKVFDLALALQLPQCLI-------
-------------------STTAIEA----SRGFYPRRHTAVPE------------------VV-------------------APSVERGPDPAAHLGEC
LCQWLGVDTLDDEDSLYELGADSLTLLDLIDEVQSRLGIGLQLSQLSHKVSLREILTLIEGSG---------
>tr|A0A0F4QXF9|A0A0F4QXF9_9GAMM Uncharacterized protein OS=Marinomonas sp. S3726 GN=TW85_14780 PE=4 SV=1
------------------QLPETDWFLQESWLRGESLEGNKAFNKHYVLIDNPNQQGKQLAETQVRYFS--NL----------LETHELEPLE-------
-----NFN--A-SYSSTLSQGLSNDSDLAPFGFKQIFNDWNDLINLIQSKLISKQSIKIINLVQGSAQILGE-SLNPTSALLLGLLQTCPIEFENLKYTV
LDLPPTSEK--LIL-NALLKLE--SLSSGHYAIRGHFLWQKHYQRSINVFEKTEALDKKGRKEKVYVLTGIGGIGEALIKHLSKDSNNKLICLSRSSMT-
-LD-TKLA--------------VNRLKCDITDLMSMKWVKQQIQAS-FGDVYALVHLAGKSGSGMMRLLDSEKTIDKMSAKVLGAINVEKTLLSLKPKKV
MYFSSMSCVNAIAGQTDYCASNHFLDLLAKHQNQVPDTEFISVNWPTWQGTGMASEV--------ERNDAITPEQGASLFSSTLEQGSSQYLI-------
-------------------SPLSDHD----KTAFFKEINSNLIP----------------------Q--------------R-AVENKEAQTLESLITNL
FKDCLGLDDISKEVCFYDLGGDSLTVLDLFDALEASFPGKISLKELNQNVTIDRLTKLISNDE---------
>tr|A3YFF7|A3YFF7_9GAMM Amino acid adenylation OS=Marinomonas sp. MED121 GN=MED121_00695 PE=4 SV=1
------------------QQAESQWIMKESWQREKRLSANKYSAANYIIIDDLADNGTLLAEAQSHIQQQTQLQTQQELIYPSLDKINYEEIS-----QR
LAINAQFN--PHSYHDTTPVNL---DDYSHSYSDSYYLSWCKLIRFFKTWSSLNTSLEFINLVQGSAEVLGE-DIRPEVGLLLSFSQTLDIEFDHLRYRV
LDLEPSYQC--DNLSQAIPVLA--NSDQAHYALRGQYIWRKTYQTCHDTLPTATRVNKTEQTVIYLVTGGTGGVATAITETLLSQANTRVISISRSKGA-
-LD-PTQV--------------LNHIKCDVTDIMAMEWLSTLIKET-FGKITGVIHTAGAPGTGLIRLLDEDQATQNMAAKIQGAINIEKTFVKLKPQIV
MYCSSMSVIDAIAGQTDYCAANHFLDLIAKKQNQTNSTQFVSINWPTWNKTGMAKDI--------EPTAAINQRQGQSLFKKLISAQDNQYLI-------
-------------------SPLDRDN----RSRLFSQINRKNEL------------------NVDAI--------------H-KTEANNTASIRTYLDSL
FKTSLGLEEIDHNRCFYDLGGDSLSILDIFDALQKRFLSKVTLADLSHEVSINRLLSLLETSS---------
>tr|A0A0Q7VFN9|A0A0Q7VFN9_9ACTN Non-ribosomal peptide synthetase OS=Streptomyces sp. Root55 GN=ASD51_28625 PE=4 SV=1
------------------RLPADRWMHQPQWTRLRRARTDESVTRTAVIVAGGRTDPAAWRELERRYARVVWLVPGKDLIRIDDDHYEADPADAGHLAAV
LAEASAPGGTAVDWLHALPLAIDGDVGERS-LDTARWACLDTVAALSRAVADRRDRPRVWLLSCGAQPVTGP-VRRPEAGLLAAATQVPNQEL-GAELRW
LDLPGPDP---TAWSAFLPDLFLDPPETSVVALRDSFWWHRAIHPVAALR-TESREAWAWGTGTYLVLGGTGGIGAVIAARILRRPESRLVLLSRNALPA
LTP-WSDR--------------ITLVRADLAAEET-GDIAARLAPHLDSGLAGIVHAAGTAAGGLIALREAESARAGTDAKLRGALLMERLIDAYDPGHA
VYCSSMASLFGGVGQFDYAAANGCLDAFAHYRAGNTRTVRTGIGWDIWREAGMARSALGHDEQHRRHLLGLTSDEGAAVFEQAMRLQLPHLWV-------
-------------------NTTDLSQ----ARSFYERPPTAVET------------------ARGPA--EG--------AQP-TPHLPPGRDRVAQLGDV
VAWLLGVDDVGTDVSLYDLGADSLMLLELVDQIKQRFGTDLDLSRFSHRVSVAEIADLIDATA---------
>tr|M9TPD2|M9TPD2_9ACTN Long-chain-fatty-acid--CoA ligase OS=Streptomyces sp. PAMC26508 GN=F750_0334 PE=4 SV=1
------------------RLPADRWTHQPQWTRLRRARTDVSPTRTAVIVADERTHPMAWAELERRYTRVVWLLPGKDLVRIDDDRYEADPSDTGHLAAV
LLEAGAPGGTAVDWLHALPLAIDGDIGEES-LDTARWACLDTVAALSRAVADR-DRPRVWLLSCGAQPVTGP-VRRPEAGLLTAATQVPRQEL-GTEMNW
IDLPGPDP---APWAAFLPDLLLDPAETSAVALRDSFWWHRAVHPVAARS-DTRGETGARSIGTHLVLGGTGGIGAVLAARILRHPENRVVLLSRHALPA
LEP-SRDR--------------ITLVRADLALEEP-ADLADRLAPHLGGGLAGIVHAAGTAAGGLLALRDAETARRGTEAKLRGALLMERLIASHHPGHA
VYCSSMASLFGGVGQFDYAAANGCLDAFAQYGGDDTRTVRMGIGWDVWREAGMALSALGHDGQHQRHLLGLTSDEGAAVFDQAMRLQLPHLMV-------
-------------------NTTDLAQ----ARSFYERPATTEET------------------PHPPT--EA--------ARP-T----PGHDRVAQLVDT
VAPLLGVDDVATDASLYDLGADSLMLLELADRIEQRFGVDLDLSRFSHRVSVAEISGLIDAAA---------
>tr|S3NHI1|S3NHI1_PSESY Mixed non-ribosomal peptide synthetase/polyketide synthetase OS=Pseudomonas syringae pv. syringae SM GN=PssSM_1825 PE=4 SV=1
------------------RQPLADWFYQRQWQRVNRLRTKPTGRDVLVVCSHERLDATTLGSLQGVYRHVIEVQAGNGYQQLGPNRYELDPLDPVAFGRL
IATLDQNGASELDWLHALPLSVGGSVDEQS-LAAAQWACLDTLSALLQAWGQQKSVLRLWLLSWQACPVNGQ-VMRPELAALAGITEVAPQEY-PIRCHW
LDLPTAQL---STQALHLAALLAEASLPRRMAIRDGYLWQPQLLASPLAN-PMADSNLLLANGTFLVLGGTGGIGRTLCEHLLQSSQRRVVLLSRGGEKE
LHA-YASR--------------IDSIAADIADLARWPTVLEHLRER-YGHFDGVIHAAGTGAGSLIRQRDAQVLSEAMASKTRGMLAVEALIEKMTPGFV
LYCSSMSALFGGAGHLDYAGASAVLDGFTHYRPHANGCVRLGINWDIWRDVGMAAASGVGDDAHQRHMAGMSAQEGCRVFDAAMTAQLPQLLI-------
-------------------STTDPDT----ARQFYPVRHSAGST------------------LADTAPV------------L-TADTEAPDRLPEHLHDC
LCKWLGVSALQPDASLYELGADSLTLLDLIDELQAATGVVFQLSQFSHKVSLAEVLTLVQASG---------
>tr|A0A066UCL1|A0A066UCL1_9PSEU Peptide synthetase OS=Amycolatopsis rifamycinica GN=DV20_11295 PE=4 SV=1
------------------RLPEAQWLHQPTWVRLRRAGDAVSSGRTLVLSGEGPLTAP---ALDAAYARVVRVHASDHFARRDTDTFEADPADTAHLRRV
LDALP---DTGIDWLHTLPLGITGPLGEAS-LRQAQWACLDTPAALLRAAHD--RPLRTWWVSAGAAPANTP-VTRPEAGLLAGITAVGPQES-GIPGHW
VDLPTPGL---DGL----ADLLTGPTPPERVALRAGFWWTQESAPVTA--------EPSTMDGTVLVLGGTGGIGTAVAEELLTRTTSRVILLARDPREP
LEP-WADR--------------VDLLAADLTKTTA---------DEIPGPLTGIVHAAGSPGGGLIATRGEGT----QDVKLAGALLTEELIERDRPAFA
VYCSSLSAQFGGTGQLDYAAANGFLDALAHREG---ATALLSIAWDVWRDSGMAVTALETDARHQAHLAGLSDDEGRRTFARALGTGLPQLLV-------
-------------------ATTGLDT----ARTFHERETTPAK------------------------------------------------PAEADLTEE
VRALLGVAELDPDVPLYDLGADSLTLLDVVDSVKRLYGVDLDLAWLGPEVTMAALLAKLDAAA---------
>tr|C6WEG6|C6WEG6_ACTMD Amino acid adenylation domain protein OS=Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971) GN=Amir_3
------------------RLPEAEWLRQPTWIRLRRTAGATRTDRVLVISGEGPLTAP---ALDAAYPRVVRVHAAERFARLGPDAFEADLADTACLRRV
LDSLP---AQEIDWLHTPPLGITGPLGEAS-VRHARWACVDTPAALLRAAHD--RPLRTWWVSAGAAPATTG-VTRPEAGLLAGVGAVGPQES-GIPGHW
VDLPGPDL---APL----ADLLTGPTPPARVALRAGFWWAEDDAPVRA--------EPLAVDGVHLVLGGTGGIGAAVAEELLTRGAGRVVLLARDPRDA
LTP-WADR--------------VDLLAADLTTVTA---------DAIPGPLAGIVHAAGNPDGALIATRGEGT----QAVKLAGALLVEQLVERDRPAQV
VYCSSLSARFGGVGQLDYAAANGLLDALAHRDG---PTARLSIAWDVWRDTGMAVTALRTDARHQAHLAGMSAEEGRRTFARALDACLPHVLV-------
-------------------ATTGLDN----ARAFHERETAPTAS------------------PA--------------------------GDAGAELTEE
VRALLGVAELRPDVPLHDLGADSLTLLEVVDAVKRLFGVDLDLAWLGPEVTMAGLLAKLAEAG---------
>tr|A0A0H3D460|A0A0H3D460_AMYMU Non-ribosomal peptide synthetase/polyketide synthase OS=Amycolatopsis mediterranei (strain U-32) GN=AMED_3962 PE=4 SV=1
------------------RRPETAWLHQPTWVRLRRATTAAPTDRVLVICGEGPLTAP---ALDAAYPRVVRVQAADRFARPSPDTFEADPADTAQLRQI
LDVLP---DTGIDWLHTLPLGIAGPVGEES-LDRARWACLDTPAALLRAAHD--RPLRTWWVSAGAVPANTP-VTHPEAGLLAGVTAVGPQES-GLPGHW
VDLERPDL---DRI----ADLLTGPTPPERVALRAGFWWTQGSAPVAA--------EVELHDGTYLVLGGTGGIGTAVAEELLTRTSGRVILLARHPFEA
LKP-WADR--------------VDLLAADLSTVTA---------DEIPGPLAGIVHAAGTPAGGLIATRGAST----PTGKLAGALLVERLIERDRPDFA
VYCSSLSAQFGGAGQLDYAAANGFLDALAHRDG---PTARLAIGWDVWRDSGMAVTALETDTRHQAHLAGLSDEEGRRTFARALATGLPHLLV-------
-------------------ATTGLDA----ARAFHEREATPVK------------------------------------------------PAAADLTEE
VRALLGVAELDPDVPLYDLGADSLTLLDVVDSVKRLYGVDLDLAWLGPEVTMSALLAKLAEAA---------
>tr|A0A0Q0C5W6|A0A0Q0C5W6_9PSED Non-ribosomal peptide synthetase/polyketide synthetase OS=Pseudomonas tremae GN=ALO43_00988 PE=4 SV=1
------------------RQPVADWFHQRQWQRVRRLNQNMPRRDMLVVCSQERLDSTVLGCLSEVYRQVIEVCAGNGYQRLGPDRYELDPLDSSAFSRL
IAELTQRALTELDWLHALPLSVSGAVNEQS-LAAGQWACLDTVCALLQAWGQRTMVLRLWLLSWQACPVNGD-VQRPELAALAGITEVAPQEY-PIRCHW
LDLPEPRL---SLYARPLAALLADALLPRRMAIRDDYLWQTRLQASPLVA-PATVSNLLPVDGTFLLLGGTGGIGRTLGEHLLQSSQRRLVVLSRSGNDN
LLG-YRSR--------------IDLIAADIADLARWPAVLDSLRQR-YGRFDGVIHAAGTGAGSLIRQRDAQTLAASMASKTLGMLAVEELVKQMTPGFV
LYCSSMSALFGGAGHVDYAAASAVLDGFAHYRADSDTCVRLSINWDIWRDIGMAAAEGVGDAAHQQHLAGLTAQEGGQVFDAALGAQLPQLLI-------
-------------------STTRLET----ARQFYPLRHGASSP------------------TD-----------------I-KLAGQSDTDLRERLQDC
LCKWLGVPSLDEEASLYELGADSLTLLDLIDELQAATGEVLQLSQFSPTVSLREVLMLVQSSE---------
>tr|A0A0P9Y0F6|A0A0P9Y0F6_9PSED Non-ribosomal peptide synthetase/polyketide synthetase OS=Pseudomonas syringae pv. primulae GN=ALO52_05082 PE=4 SV=1
------------------RQPVADWFYQRQWQRVRRLSSRPLPRELLVVCSHEALDDTLRSCLKNVYRRVVEVTAGNGFQRLATDRFVLDPLDTLALTRL
LDILAGDQPLELDWLHALPLSVTGRVNEQS-LAAAQWACLDTVSALLQGWGKRTPALRLWLVSWQACPVYGE-VKRPELAALAGITEVVPQEY-PVRCHW
LDLNSAQL---AARPEALAALLADAAAPRRMAIRDHYLWQPHLQASPVMA-STVDPCLLPQDGVFLVIGGSGGIGRTLCEHLLRNDQRRVVLLTRHGEDA
LQA-YRSR--------------IDPVQADIADRTVWPQVLEQLERR-YGHFDGVIHAAGVGAGSLIRHRDARTLSEAMAAKTLGMLAVEELIQQMTPKFV
LYCSSMAALFGGAGHLDYAAASGTLDGFTHYHPNASDCVRLGINWDIWRDIGMATGAGAGDAVHQRHLAGMSAQEGCQVFDMALSAQLPQLLI-------
-------------------STTSIET----ARQFYPVRHGASAA------------------AQPVAQASA--------STA-PGKEEQGADLRTRLHDC
LCKWLGVTELDEDDSLYELGADSLTLLDLIDELQAATGEVVELSRFSHKVSLREVLALVHADS---------
>tr|G8XGR6|G8XGR6_STREN Amino acid adenylation domain protein OS=Streptomyces cattleya (strain ATCC 35852 / DSM 46488 / JCM 4925 / NBRC 14057 / NRRL 80
------------------RLPESDWLHQPHWARLHRAAT-TA-TRLLVIVTGEPLPAPAVHAFQEVYARVVRVVAADAFARHGQDEYRADPADPESLRLL
LDAVADAGADGIDWLHALPLAVTGPVGPKA-LDRARHACLDTPAALVRAVAAGTPPVHPWWLSYRARPADGP-VRRPELGLLAGAAQVTAQES-SLDGHW
LDLPGADP---ADWAAPLAALTAGQDTARELALRQGYWWHQVTLPVPAP-------DLPADGGDHLVLGGTGGIGTAVAAWLLDHTDGRVLLLSRTPRDE
LTG-HADR--------------VTLVEADLATTPA-PDLAALIAGH-TSRLHTVVHAAGVPSGALIATRDATAMRAGTAAKLDGALLMEEVIARHRPRLA
VYCSSMSALLGGVGQYDYAAAAGLLDAFAHHRPDDTATTRVTVDWDVWREAGMALRTSRTDPRHQAHLAGLTVAEGKRVLARALGAGLPQLLV-------
-------------------SVTELEE----SRVFYTPPATEAPA------------------T------AP--------AR-------PATTPAGLLTDW
LCRWLDVDHLDPDAPLYDLGADSLTMLDLISEVKRHFDVELDLASFSHRVSLGEIVSLLAGPV---------
>tr|A0A0M9XJ16|A0A0M9XJ16_STRRM Peptide synthetase OS=Streptomyces rimosus subsp. pseudoverticillatus GN=ADK70_35525 PE=4 SV=1
------------------RLPETDWLHQPHWVRLSRAVPAPAPGGLLIVMTAEPLPPEALRFFEAGWSRVVRVGAADAYARLTDDVYEVDPADPASLRQL
LDALGGPGETVIDWLHALPLAVDGPVDEDA-LTRARWACLDTPAALLQAVAGLAEKVRPWWLSYGAQPVEGP-VRRPELGLLAGVCEVAPQEC-AVDGRW
LDLPSREL---ADCAQQLAALSGRGTLPRRLALRQGYWWQQALLPVPAPT-SA-PSVLPDEAGTYLILGGTGGIGSSIAAWLLERSDCRVILLSRQPRAE
LTA-WADR--------------VELVEADLAETPT-ETVLTRIDAV-AHRIDGIVHAAGTAAGGLVTRRDAPAMRQAMAAKLHGALLAERLIERHRPAFA
AYCSSMAAQFGGIGQFDYAAANGLLDGFARHRAGEEATLRIGIDWDIWSEVGMARDALRTDARHQAHLAGLAVKEGRQLFARALELQLPQLLV-------
-------------------STTPIEE----ARAFYAAPADAVSP------------------VTPGT--AT--------AS-------ATASASAELTDW
LGRWLGLDELDPDASLYDQGADSLTMLDLIGKVAEHFGVDLELSQLSHQVSLNEVLVKAGAEP---------
>tr|J2X6U7|J2X6U7_9PSED Amino acid adenylation enzyme/thioester reductase family protein OS=Pseudomonas sp. GM25 GN=PMI24_04890 PE=4 SV=1
------------------RQPLADWFHQRQWVRTRRLSGNATAREVLILCSHDAPESTLLASLNIVYRRVIQVRAGNGFKRLSPDRFELDPLDTEALNRL
LAEVA--ELGELDWLHALPLAVSGAVSEQS-LDLAQWACLDTVSALMQAWGQRTTRLRLWLMSWQACPVDGA-VQRPELAALAGITEVVPQEY-PVRCHW
LDLPSSRL---EAQACELAALLGDVSLPRRMAMRDGYLWQPRLMPQPLTG-PTTTSGLLPEDGTFLVLGGSGGIGRTLCEHLLQAPARRVVLISRQGQES
LAA-YASR--------------IDCIKADIADLPRWPQILDQLAVR-YGRLSGVIHAAGVGAGSLIRHRDPRKMAEAMAAKTRGMLAVEALIEHLTPGFV
LYCSSMSALFGGAGHVDYAAASGVLDGFTHYRPNPDTCLRLGINWDIWRDIGMATTSNGGDAAHLEHLTGLSAEEGCRVFDLAMATQLPQLLI-------
-------------------STTGIDT----ARRFYPVRHGAATP------------------VE----------------------APKGVDLSVRLRDC
LCKWLGVAELEDDDSLYDLGADSLTLLDLIDELQAATGEVFQLSQFSHKVSLSEVLGLVSTAT---------
>tr|A0A0L6FSM4|A0A0L6FSM4_9PSED Thioester reductase OS=Pseudomonas sp. 250J GN=DA83_25030 PE=4 SV=1
------------------RQPLADWFHQRQWQRVRRLRKSMAVRQTLVACVHEAVDDAVLATLGRAYRRVVQVQAGQGYRQLATDRFELDVLDTQALGRL
LEALP----GELDWLHALPLSVTGAVDEQS-LAAAQWACLDTPSSLLQAWGQRDADLRLWLLSWQACPVQGA-VARPELSALAGVTEVAPQEY-PLRCHW
LDCPSPSL---GEHANTLATLLAEEALPRRMALREGYLWQPRLVPSPL---PSPAAPGLAERGTYLILGA-GGIGRTLCQHLLRAADRRVVLLSRSPV--
ADL-DHER--------------VDWVQADLADLQRWPQVLEALARR-YGRFDGVIHAAGIGAGSLIRQRDARQMAIAMAAKTHGLLAVEALIARMAPDFV
LYCSSMSALFGGAGHLDYAAANAVLDGFSHYRAAGEGCLRLGINWDIWRDTGMATRGNGNDAAHQQHLKGLSAQEGCEVFERAMAAQLPQVLV-------
-------------------STTALHS----ARRFYPRRHGAAAP------------------VD---------------------ERPRQDDLPTRLRDC
LCQWLGVDSLEDDDSLYDLGADSLTLLDLIDELQRATGVVVQLSQFSPHASLREVLALVDADP---------
>tr|A0A0F7XY92|A0A0F7XY92_9PSED Thioester reductase OS=Pseudomonas sp. CCOS 191 GN=CCOS191_2530 PE=4 SV=1
------------------RKPLADWFHQRQWQRVRRLATAAV-QRTLVVCAHDAADEGVLATLGQACQRVVHVRAGKGFRQLAADRFELDVCDAQALGRL
FDALP----GALDWLHALPLSVSGAVDERS-LATAQWACLDTPGSLLQAWGQRDASLRLWLLSWQACPVQGA-VARPELAALAGVTEVAPQEY-PLRCHW
LDLPSPAL---GAHASALATLLGEEALPRRLALRDGYLWQPRLVPSPL---PAATAPSLAHTGTFLILGA-GGIGRTLCQHLLRAEGRRVVLLSRSPT--
VDM-DHPQ--------------VDWVQADLADLTRWPQVLEDLACR-YRHFDGVIHAAGVGAGSLIRHRDAREMATAMAAKTRGLLAVEALIARMTPGFV
LYCSSMSALFGGVGHLDYAAASGVLDGFAHYRATAEGCLRLGINWDIWRDTGMATRTHGSDAAHQQHLKGVSAAEGCEVFERAMAAQLPQLLV-------
-------------------STTSLGT----ARRFYPVRHGVAAQ------------------PQGV-------------------VQASGSDLAARLRGC
LCQWLGVDALVDDASLYDLGADSLTLLDLIDELQGATGQVVQLSQFSPQVSLGEVLALVADEP---------
>tr|Q1IA16|Q1IA16_PSEE4 Putative Polyketide Synthase (Terminal component) OS=Pseudomonas entomophila (strain L48) GN=PSEEN2718 PE=4 SV=1
------------------RKPLADWFHQRQWQRMWRMAGPAPVRQTLVVCSHAAADETLLGTLGAAYRRVVHVRAGDGYRQLAANHFELDVLDAQALTRL
LAELP----GDLDWLHALPLSVGGAVDERS-LATAQWACLDTPCSLMQAWGQRDANLRLWLLSWQACPVQGA-VARPELTALAGATEVVPQEY-PVRCHW
LDCPSPSL---LEHAKPVAALLAEDALPRRMALRDGYLWQPRLVPSPL---PLAAPNTLPDHGTFLILGG-GGIGRTLCQHLLRAPGRRVVLLSRSATEA
WQV-DRER--------------VEWLQADLADLMRWPQVLEHLAQR-YERFDGVIHAAGVGAGSLIRQRDAERMASAMAAKTRGMLAVEALIARMNPGFV
LYCSSMSALFGGAGHLDYAAASGVLDGFSHYRAPGQGCLRLGINWDIWRETGMATEASGNDAAHQQHLKGLSTQEGCEVFDRAMTAQLPQVLV-------
-------------------STTALAH----ARRFYPVRHGATAP------------------VE---------------------VPPKQDALPARLRDC
LCQWLGVDALQDDASLYDLGADSLTLLDLIDELQRATGVVVQLSQFSPTVSLREVLALVGNDP---------
>tr|A0A0Q0C6J2|A0A0Q0C6J2_9PSED Non-ribosomal peptide synthetase/polyketide synthetase OS=Pseudomonas syringae pv. tagetis GN=ALO44_05543 PE=4 SV=1
------------------RQPMADWFYQRQWLRVRRLGTQTNLRGVLVVCAHERMEAAVLDSLQSVYRQVVEVQAGNGYQQLGPSRYELDPLDPLAFSRL
IAALEHNGATELDWLHALPLSVGGVVGEQS-LATAQWACLDTVSALLQAWGAHKTALRLWLLSWQACPVNGT-VLRPELAALAGVTEVAPQEY-PIRCHW
LDLPAARL---DTQARQLAALLADMSLPRRMAIRDDYLWQPQLQASPLAE-PAAVSNLLPANGTFLVLGGTGGIGRTLCEHLLQSSQRRVVLLSRRSEQS
LHA-HASR--------------IDSVQADIADLARWPGVLEQLRER-YGQFDGVIHAAGTGAGSLIRQRDARVLSEAMASKTRGMLAVEALIEQMKPGFV
LYCSSMSALFGGAGHLDYAAASAVLDGFTYYRPNANGCVRLGINWDIWRDIGMAAAAGICDEAHQRHLAGMSAQEGCRVFDAALTAQLPQLLI-------
-------------------STTELNT----ARQFYPARHGGDST------------------VIEAAPA------------F-AAET----GLRERLHGC
LYKWLGVSALEENDSFYELGADSLTLLDLIDELQAATGVVFQLSQFSHRVSLLEVLTLVQQAA---------
>tr|T1SF54|T1SF54_MYXFU Hybrid polyketide synthase/nonribosomal peptide synthetase OS=Myxococcus fulvus GN=mxnI PE=4 SV=1
-------------------RDAPPSLYRSVFVRSELASGREKGLGPVLVLARDARFVERLREGPGERPQLVWARPADRFAERDGLAFDFDSRRPEELARL
LDTLRTRGLAPSVVIHGFSYGRDE-------LQAQLQDGALSVFHLSKALLRERNERPVSFLYVY----PATELPQPLSAALTGLARSVRLETEGLKLKV
VQVESPEEM-----ADAAASELAPDADGDSFVYVETLEPLCFDEA---GA----AQPRFKDGGAYLITGGAGALGLHLARHLTQRVRARVALCGRA---R
LSEAQQREVDGLR----ALGAEVDYFVTDVTDFSDVEMLADTLRARYG-GVQGIIHAAGQRQDQLLARKDAAQFAAVIAPKVFGTINLDRAFAAERLDFF
VVFSSALTGNVGQ--TDYAFANAFLKGFTAFRE-GL-VLNHAISWPYWKEGGM----KVDFIRSFFGTQPLETAAGLRAFEEIVGRGIPELVLSPGAVPA
RFLKDS--------------------------------AVATQAMV--------APVRHEPAP-------------------------AQRAIREEVRRI
AAGLLQMTALDEHKDLAEYGYDSISFTELATALNAAFGAELTPAVFFELTPLNALVAYLEAR----------
>tr|D7RK25|D7RK25_CORCK CorI OS=Corallococcus coralloides GN=corI PE=4 SV=1
-------------------KPEAATLYRTVLERADVTP--RGVSGPVLVVSRDAGFVEQLRSGAGARPSLVWARPAERFQARDDWTFDFDARRPEEPGRV
LEALRARKLSPAAVVHAFTYDADA-------LKAQLQDGALRVFHLCQALLRDGLERPLPFLSVF----PASEAPHPLSAALKGFARSVRLESDLLNLTV
VQAERPESM-----ADAAFAELSAGTTAEPFVHVEVLAPMSSGEA---EP----ARPVLPNGGTCLITGGAGALGLHLARHLARRPGVRVALCGRS---A
LTEATRARLESLR----AQGADVEYFVADVTEPGDVELLVDTLRARYG-GLQGVIHAAGERRDARLVKKTAAEFEAVLAPKVTGTLLLDRALAAEKLEFF
AVFSSARTGNVGQ--TDYAFANAFLEDFRAFRD-GL-CQSHAIAWPYWREGGM----KVDFIRSFFGTEPLDTATGLDAFDAVLGRRLPELVLGRGA-PA
RFLKAA--------------------------------AEPS------------LPERSEPVPAVAP-----------------PRPAELPGLLDEVRHI
VAGLLQLASLDPRKDLAEYGYDSISFTELATALNTAFGSELTPAVFFELTPLDALVAHLRER----------
>tr|D2DIP7|D2DIP7_9BACT SupA OS=uncultured marine bacterium 1k6 PE=4 SV=1
-------------------EGVKDLLYEIVWKDRPLVPGDFKVRQRLQVDEVHRKLFRRMLAPEGGGDPLPEAAVGVEFARWMEW-WRFADHY-LAGPAW
VLAA-AEALAAAVVIPDYRRGLRQ-------ASR-VDSLSVSEGALEEGLLGGRILVGLAFGTFGPE-T---VTEEMVAPAPSGFPATSLATIPTAAIQL
AQAAGAEVF-----AQAYLRSLGAGESLTEAA-MRGARHIGKLTPS--PI----ERGSLRADRTYLVTGGLGGIGCAVAGWLADRGGAI-VLNGRRE--P
DA-PAREAISALQ----ARGGTIRAELADVTDGAAVDAMLARMDASLP-PLGGVIHSVGVLSDAALTNQTWQSFEDVLWPKMLGAWHLHRATADRGLDLF
VLFSSGVLGNAGQ--ANHGAANAFLDQLAGHRR-AQG--GQSIAWGAWAGLGEAERERIAGQLEASGTGWISPRQGLRAFERLVQKDTAGMVASVDWSQA
PLLESL--------------------------------LATED---------------EVPAEQGDVQADLL-------SGLSLALPEAREQVVSFLQNE
LQAVMRLNLPPPVAEFSDLGMDSLMAVELRNRLNRAFAGEYSNTVVFDFPSIAELARHLAGE----------
>tr|A4U8P6|A4U8P6_9BACT Polyketide synthase (Fragment) OS=Aplysina aerophoba bacterial symbiont clone pAE27P20 GN=supA PE=4 SV=1
-------------------ESFQDLLYETVWQDRPLAPGDFRARQQLQVLPEHQRLFRRLFAGDGGDDPLPESMPRDEFADRMGW-WRFADDC-LASPAW
VLAA-ADDLAAEAVVPDFRLGIRQ-------AARATERLTLPDGALEEGLLGGHVRVALAFGTFSSE-A---VMEEMVAPAPPHVPTTALATMPTAAIQL
AHAAGAEVF-----AQDYLRSLGAGESMGEAP-MRAARHVGKLTNS--PL----ETGRLRQDRSYLVTGGLGGIGCALAGWLADRGGAI-VLNGRRD--P
DP-EAVEAIAGLR----ERGVRVQVELADVTDPEAVDAMLERMDAKLP-PLAGVIHSVGVLSDAALTNQTWESFQQVLWPKMLGAWHLHRATRQRDLDLF
VLFSSGVLGNAGQ--ANHAAANAFLDQLAGHRR-ALG--GLAVAWGAWSELGEAERERIARQLEAAGTGWITPQQGLRALETLIRQDVAGMVAAMDWPSV
RFLEEL--------------------------------LVVSG---------------RGADEDKESPADLL-------SQLRVSQAAEAEGIATFLQKE
LQAVMRLTLPALSVGFFDLGMDSLMAVELRNRLNRAFTGEYSNTAVFDYPDVTKLAQHLAGE----------
>tr|A4U8R3|A4U8R3_9BACT SupA OS=Aplysina aerophoba bacterial symbiont clone pAPKS18 GN=supA PE=4 SV=1
-------------------EGIDDLLYEIVWRDRSLAPGDFIARERLEVGDHHRRLFRRMLAGDSSGAPLPGGLTSDAVAGDMAW-WRFADTY-LATPAW
VLAA-AADLAADAVVPDHRFGRRL-------GARVADRLILPEGSLDD-FMGGRVRVGLTFRNYGSE-T---VTEKMIVAAPPGFSVSELATFPTAAIQL
AQAAGAEVF-----ARDHLRSLGAGEPVAEVA-MQGARHIGKFTNS--PL----ARGALRGDRSYLVTGGLGGIGCAVAEWLADRGGSI-VLNGRRS--P
DP-DVERVIEALR----KRGAEVRVEIADMTDPPAMDAMMARIDEDLP-PLAGVIHSVGVLSDAAIGNQGWENFETVLWPKILGAWHLHRATENRDLDMF
VLFSSGVLGNPGQ--ANHAAANAFLDQLAAHRR-SLG--GQVIAWGAWSEIGEAERERMSRRSASGGLEWIDPQQGMRAFDRLVREDATSVVLARDWTRP
PLLEDL--------------------------------LSDGA---------------DD-GADDSLADDLI-------TRLQDAPAAMREDVASFVQGE
IKAVLRLRPPAPTVGFFDLGMDSLMAVEFRNRLNRAFAGAYSNTVVFDYPDIAALSAFLADE----------
>tr|A0A088YCG4|A0A088YCG4_BURPE Methyltransferase domain protein OS=Burkholderia pseudomallei GN=DP46_3534 PE=4 SV=1
-------------------RALGPASPAPYYAQADATDA--------------RRAIEAVRQGAVFANHAIASVPAHRFDEILDQSFSFSGA--ARLGAY
AAATIVRSIAPVAAF--WGFWE-----------TSVEDSALGSFACFERFVGQNPEVEHLMQVLPGEAAPGQPAPAPLRAAPDGAA-------------A
SEAAPPDGA-----ADAWLARLTGPRWDETLIFARGWLRIVDIAEP--DA----GEHVWRDWARYRFDTPAAR-GRRAQIDLADVCRALPVLAGRLP--A
ADVGSMERVEGVY----RDNPISDYFNAVQADIRHVRAWIDAGRREPI-RILE--VGAGTGGTTALALERLRPYAAAIGEDVSAFLAFGARAGYLRTALF
DVERPAQRMPAGR--YDIVIATNVLHATRQVRG-ALRVKGLLEGWWLHEDSSLRESPVLARLLEDEGFGAIAFA-------ARDAHALGQVCATSDGVRQ
RAGEPS--------------------------------GHSSRSTH--------AGEAPAPASAGRAGAAP----------AASPAGTAREPVVAAIHRA
LQQSLKLARIGDHTPFLDYGIDSILGVRFVDSLKQALDVPLNTAVLFDYPTVERLADFIVAT----------
>tr|E5ARL9|E5ARL9_BURRH Modular polyketide synthase (EC 2.3.1.-) OS=Burkholderia rhizoxinica (strain DSM 19002 / CIP 109453 / HKI 454) GN=rhiD PE=4 SV=
-------------------LPAGLSLLAPQWLVADHASTLPEQHPQIEFLPSLATTIDGIAACAP-FQRLIWLAPQTDFANQRLVSYREGGVYAGGIGEW
LGRRIHRKLAALACNRCWGYWGSV-------GVVAGYRARMAEMAALDQLLAGV----GLIKLLEPMTIAGIDSTQ---------LHCYPLEKPPVWTNA
QRLGPPPQH-----HDRLLLALTANLLRESLLLDDQGQ----LTAI--PA----AASLWSQWRQASDEWR-RDGDLHAQLQLVETCRALPILRGEKQ--A
TEVGSMSLVEDIY----KNNKISDYFNEALGEV----DIARRHAEGNR-PLRILEIGAGTGGTTAGLISKLRPWRHQIAEDLSAFLHFAPDAPYLRTAIF
DVSKAEQGISTNQ--YDLVIATNVLHATPDLRC-TLQAKGLLEGWWLYDDEALRICPGLSRLLQSQGFGDIAFP-------VAGSHGLGQIVAVSDGVRL
PAQQRV--------------------------------MPVADAAI--------APVAIAPVAAIAPRVTPTI------AEGEIDEAVLAKQCRQLITEV
LSKLVNIERLQRDVAFDRYGIDSILQISLIQALEKATGE-LSRTILFEYNTINQLTDYLLSE----------
>tr|S0FP35|S0FP35_9FIRM Polyketide synthase like protein OS=[Clostridium] termitidis CT1112 GN=CTER_0304 PE=4 SV=1
--------------------------YDMGWIIESLDKQAPEWKTAL-VFRDDAGAADVITGLKGSILEVIEVTFGSGYQKTG-QSSYIISGTEEDYLKL
MTELKTRDID--KIVHLSTVSRS-DTMFERSCDDVQNRGIYSLFYLTKALAAYNNEISIDLLSENVEQVTEEDSPD--NAAFFGLGKVAAQENLKLKLKC
IDFDQAT------ALDCIINEVISECKAQRVAYRKGNRYIPEFSIAELNTSQE--ELNIKNEGVYVITGGAGGLGLEIARYISEKGNTNIALINRSKLPD
--AEQWDDIRSIRNI-QTSGSKVVCCKADISNEEETKEALDSLRERFG-HINGIIHAAGVAGDGFLVIKDSDIFSRVMAPKINGTQILDRLTIDDKMDFF
VLFSSMASVTGGMGQGDYTAANTYLNSFAQRRN-KAGKRTVSINWPGWKETGMTVDNNTDDNFPFRA---LTTSKALNIFEDALRSGRCVIYTGE----L
NIP---------------YL---------------SSVTDSLPVKLSGKISINKYLLDK-----NKTKHQAEVK---DTNAQAAANSASSNSLENKLALI
WGSVLGIKEIDVYDNFHDMGGDSILATQLLKEIDKEFPEVISISDIFTYPSVSQLAGFISGK----------
>tr|H2JD34|H2JD34_9CLOT Subfamily IIIC HAD-superfamily phosphatase OS=Clostridium sp. BNL1100 GN=Clo1100_0896 PE=4 SV=1
----------------------------------------------LVIKDDSVNAESIISELKQRQNSVIEADIGTSYHRVSEYRYTVGIG-EEDFAKL
LRDTMGYGIT--QILYLSKLTSD----CGEKINQTVSQSIYTMFYLTRALVNSKGALDVVLISGYANKVTGKEEPQ--NTALFGYGKVVGQEYPDLKVRC
IDIDDN------MIAKELISEIGRENKNFLVSYRNGKRYVEVFESVIASEIPQ-NDLVLNKKGVYIITGGIGGIGLEIAKYLASKENINLALLSRTELPE
IKDDKNEKIKSLLE-IESTGSNIAYCRADVTNYEEVSAVINQLRTQ-YTKINGIIHSAGVPGAGLIITKNEDQITKVLASKIIGTYNLDRATESDELEFF
VLFSSIKSLLGGEGQSDYAAANAYLDAYTHYRN-RLGKRTLTINWPAWKETGMAADYGVN---KDNVFKAISTQDGIEAFGKALLSDMERVIIGLDYSD-
----PILS-----SEQ-------------NFIRMSQS--------------LKLKIEQELKKSVSGRNNRAK--EQIHSFVLKGKEGETYTEIEKTVGKI
WTEALGLHEINIYDDFYGMGGDSILAINIVSGIKNLMNLDINISDFFDNPSVYDFARFIET-----------
>tr|I2C4I8|I2C4I8_BACAM Polyketide synthase type I OS=Bacillus amyloliquefaciens Y2 GN=mlnG PE=4 SV=1
---------------------HPLFYYKPEWTESFIPSKSVPLTGLLLIFAENE---RQIQELSGLGCTLLFVIRGKEFAVLHDDTICMNHVKKHDYLKL
FRYIHDHYQLPEKILHLWSDSQAD-MSKGGIQKQ-LENGLFSLLYITQALIELKKIIKLTHIFQTE-N-KEQLP---LHHALGGLVKTVHQEHPNFHYQI
INITQSEGA-GAALPAIYQREFDEKRDIHFEVYENGRRFTKSYN----KAGSFDLTQPLKHHGNYLITGGLGGLGYILAKHLSEKWKANLILTGRSD---
LTEEQEKKIEYLRS----SGSTVEYIRSDVSKQSDAERIFAFAKEQFG-TLHGVFHSAGVLRDSFILRKTKEEIDQVTGSKVYGTLWLAEEIKKMKVELL
VLFSSTSAVFGSAGQCDYAFANAFLDQYAAVMT-AKAERVVSVNWPLWTSGGMNIDDEVSYMKQELGLDPLDDSDGIQALENSLCQSSE-----------
--QLIA--------------LKG------RKEKI----EDVLKR--AG------TISFHLKQQEDADLQ----------------NDELRQNIISYLKNI
MSEELKLSLIDEKQYLEKYGIDSVMIMRLTKKLEQSIG-RLSKTLFFEYHSISQLAEYFLSH----------
>tr|I2HQK0|I2HQK0_9BACI MlnD OS=Bacillus sp. 5B6 GN=MY7_1333 PE=4 SV=1
---------------------GQAIYYQTVWQRTDLNIVGGRREGSLLLFDKNE---DVSKELAALDTRVILVKPGKEFRKTGDGVFEIDPRSERDYINL
LGWLIEEESDIREAVHLWSDMPFE-KTERAIREQ-CDSGVYSLFLLQQALFKNNKPIKLLYGYFSH-L-SGEQP---LYAAASGFLRTLQLENPLISAKS
IEMEQSIAA-VH----IIRNELSDFQPSDVEIYKMQRYVKQLKTYE-PEKNSGSGDVPLRENGVYIIAGGAGGLGFTFAEYLAFQTKCCLVLTGRSP---
LSDHIRKQLRRLED----AGSSAVYVQADITNKEEAEYVVKKAKTSYG-KVNGVIQGAGIIRDSFLLNKSREEFDQVIRPKVLGTMWLNDAVEKENPDFF
ICFSSTSAVLGNVGQSDYAFGNSYMDHFMNMRS-AQDTISLSLNWPLWKEVGMQVDERVETMK-KAGFYPLEKEEGKEAFAVALSSGFS-----------
--QFTV--------------FYG------DEQ-I----DNHV------------IQADEGTGRNIESFD----------------SEKLTAETSDFIIKM
IAAEFRMDKIDAEEALEKYGLDSVMIINITNELEKHFG-ALSKTLLFEYQTAAELSQYFVEE----------
>tr|M4KVF4|M4KVF4_BACIU Polyketide synthase OS=Bacillus subtilis XF-1 GN=pksM PE=4 SV=1
-------------------------TFQEVWKEEPATLT-SKRIKTLICFLTEREQNAFASVLKNVDQTKVIFSQGEVYSKQSEYSYQIVRQEPVTFEKA
FQSIKEELGEPDAILYMWPMEDKR------CIKDH-----SCIVYLLQGMSAKLHPSRLLLAGCFED-----GLDRSYLESWIGFERSLGLVLPHTK--V
TGIFQPAEVSMDDWTRKIWAELQASAE-QTVLYQNAKRYVNHIEQTTIQ-PD---DSKLKSGGTYLITGGVGGLGYLFAKHLAKNYAANLILTGR---SP
FNDEKQKQIKELND----LGGEAMYAEADVSDPIAMGDCVKRGKDRFG-AINGVIHAAGIESDSAIFDKKIESFQRIIEPKINGTIALDEWLKNEVLDFM
CYFSSSSAVLGDFGCCDYAIGNRFQMAYAQYRNLH-NGKTFVINWPVWKDGGMKIGDETDMYLKSSGQRFLEAEEGIRMFEHILAQ-QDAVIAGQ-----
---------LS------------------RVSRFLGMTEPAIPEPA-TQAPLAQEN-------------------KDEVKTLS-----VEKRLEHDLKEH
IHTLLKIDKLNLNKNWADFGFDSIYLAKFSNVLSKHFNIEVTPALFFGYSTLQELIGFFLTD----------
>tr|W7YI66|W7YI66_9BACL Malonyl CoA-acyl carrier protein transacylase OS=Paenibacillus pini JCM 16418 GN=JCM16418_1328 PE=4 SV=1
-------------------------TFEEVWKEEPLQQNSGSRVNTLVCFLSDVEQKTAVQFFRTIEEMKVLFSQEESNGESSSTIYRVDRHDVDTYDRA
FKDIQEQHGDIDAVLYMWSLEDPG------SVQDY-----SHIVFLLQAVLAQSKPRRLLLAGQFGQE---ADLSRCYLESWIGFERSLGMIMPQTK--V
SGVYKEVAGDIADWLRKLWSEVHAETA-RTAFYQGEKRHVSHIKPTLLQ-AD---HSRLRMNGTYLITGGCGGLGFLLAKHLAKRYKANLILTGR---SP
MDPKKEAILGQLVA----LGSRAHYIQADVCDVQAMNTGLSESREHFG-SIHGAFHAAGLQSSQSFEEKELSKFHEILSPKIQGTLVLDELMQEDYLDFI
CYFSSSAAILGDFGFCDYAVGNRFQMAYAKYRNRQSSGRAITINWPVWRDGGMSIGDATENYLRSSGQRYLETEEGLDILERALFQPQLQVLAGQ-----
---------AS------------------RVHRFLGLSEETRQKDQPAARPQGKGR-------------------QAHMLGWS-----TEQCLEADLKNW
ISELLKHHKLKPDIQWMDYGFDSVLLAEFASYLSDRYQVEIAPSLFFSYTNLEQLIRYLLKK----------
>tr|A0A0M9EDL8|A0A0M9EDL8_9DELT Polyketide synthase (Fragment) OS=Candidatus Magnetomorum sp. HK-1 GN=MHK_000659 PE=4 SV=1
----------------------------------P---EKANFLNQLLCDFHEKD---------------IWHYSGNKLKQLSEKKWIIDTKTKDFFDGG
YNTINSEQP--------WIDQSKN------QEKGV-----LCLFKMIKALIEQLIDHKIQLVV-FTQGGQYNQVTNPFPASLYGFCQSLQKEHKKLDVYC
LDLHNGEP--LMDVLKAFIRNQQ----ECEMVIDSDDCYVRSLNRLQLK-PP---CNNFRKKGVYLILGGAGGIGLSLARYLSEKYQANLVLIGR---ST
LNDHKMQAIAEIES----LGGKVKYICADARNFEAMKDAVKQAKEAFQ-TIHGVVHSAIVLRNRTIKNMDESAFGEALAPKIDGSIHLYEAIKNEPLDFI
MFFSSAASVIATAGQSNYVAGCTFKDAFAFFLSNQVKYPVKLINWGYWGSVGIIANKWYKDRLKNEGILSIEPHEGMKIIERVMAYPVPQVLTGQ-----
---------KNYINVM---------FPNSRFCRFFTYNEITKKTPFTSVTPVEYAPEDKKSF-------SQPVVNALEISETD-----LKDHTQNYIKEV
FSKVLKLAHFEGDENFDMYGVDSLLTMKITDALETDFGHELSATLLYENPSIDQLTSFFLKH----------
>tr|I4CJP0|I4CJP0_9NOSO Polyketide synthase OS=Nostoc sp. 'Peltigera membranacea cyanobiont' PE=4 SV=1
-------------------------LLVPQWQRQALPKDAQVVLQGTIIVLASDDQHHHAAFVENLGQNKVPDVKSHTYTQITPQHYQFCFDNADRARGI
--------------------LDLA------N----SQ-CILGNIALLQS-LLTRK--PLR-LLQVTQGLQNGTSTNLSGAELTGLFKMLGAEYNSCYAKT
IDLDPNNS------LSQIAQEYQD---YTEICHRDGDRFVSTLAHLNSK-PQ---SQKL-PQGIVVITGGTGGIGNEVAQHLA-RQGYTLVLMGK---TT
LPPRKITNILNLEK----QGVTVELYTGELTDYAALEVYFQNIRRQYG-QITQVFHCAGCVSSPAFLHKTLDSIVSVLSPKTTALEVLHRIFEHDNLEAF
VLFSSLSSVVPKVGISDYATANAYMNYFATYQVAQGNTYYRAIQWSNWKEVGMGQL--TSQPMTKIGLVPLSTAVGLQSLDTILALPPQITVACL-----
---------ASQ----------------EQVSE-LSLV-K---EQTTKIQPVSLPKQ------------------NFPTDSNA-----LQTYVLESLSQI
LSRELHIDQIKYETSFEALGVDSIFLAGIVNKIDQWLGMRLDPSLLLQYDSISRLAEHLISH----------
>tr|G8M267|G8M267_CLOCD Putative polyketide synthase component,beta-ketoacyl synthase family protein,phosphopantetheine-containing protein OS=Clostridi
------------------------------------------------ILKDENGKGEILQILKEYGRKVKTVSIGEEYKKLDDDNYIARN-KEDDFVTV
LNDVEWNGR--IQIVHMLSLGVNC-ENGIEGVDKKIESGVISLYYLTRAIMKSSKEVELSLISNCVSDVTGSHEIVPENAALFGLGRAIRNEISLIKCRC
IDIDEQ------TELFNIAMDLIINGDFYETAYRNGKRYVQKFDSLDIKDCPD-KRVEIKSEGVYIITGGLGGIALAVAKSLALKNKVNIALISRSKIPE
REKGTDNRIIAIK-EIEELGSKVTCFSADVKDIDKVSVIVEKLRQDFG-KINGIIHSAGIPGDNFVVQKEEKAFREVLSPKIHGTWILDKLTEKDDLDFL
ILFSSVASVLPAPGQGDYAAANAYLDSFAAYRE-NLGKRTLVVNWVAWKETGMAYDTGTNID---TAFKALYTDKAIDALFTVLNKGVQRVLIGLNYDD-
---------------KMIYLKYP----LKISERIK--------SAIGIQSS---------KEKDNKVNKKKDAAVV--ELRG--RSDNDYTETEKLIGQI
WSEALGYTQIDINDNFIELGGDSIMAMNLVTQIAKATGVKLNISEVLSYMTIYELAKYMDEK----------
>tr|U4R6E3|U4R6E3_9FIRM Beta-ketoacyl synthase (Fragment) OS=[Clostridium] papyrosolvens C7 GN=L323_03260 PE=4 SV=1
------------------------------------------------YFKIRSGDDEVLKILKQRQNSVIEVDVGTVYHRVSEYRYTVGI-GEEDFAKL
ISDTIGYKI--TQILYLSELTSDC-GEKINQTVGNPSQSIYTMFYLTRALVNSKGALDVVLISGYANKVTGKEEIIPQNTALFGYGKVVGQEYPDIKVRC
IDVDDN------MTAKELVPEISSGNKNFLVSYRNGKRYVEIFESIAASEIPQ-NDLVLNKKGVYIITGGIGGIGLEIAKYLASKENINLVLLSRSELPE
RDKDKNKKIKSIL-EIESTGSNIAYYRADVTNYEEVSAVINQLRTQYT-KINGIIHSAGVPGAGLIITKNEDQISKVLASKIIGTYNLDRATENDELEFF
VLFSSIKSLLGGEGQSDYAAANAYLDAYTHYRN-RLGKRTLTINWPAWKETGMAADYGVNKD---NVFKAISTQDGIEAFGKALLSDMERVIIGLDYSD-
---------------SILSSNFK----LKIEQELK--------KSVSGRN----------------SRAKEQIHSF--VLKG--KEGETYTEIEKIVGKI
WIEALGLDEINIYDDFYGMGGDSILAINIVSGIKNLMNLDINISDFFDNPSVYDFAKFIEAT----------
>tr|A0A085WVX4|A0A085WVX4_9DELT Malonyl CoA-acyl carrier protein transacylase OS=Hyalangium minutum GN=DB31_0098 PE=4 SV=1
--------------------AELTW-FKPEWFPSALAPSVPATAGAVLVFDPDGSFTQQVDRLRGSARAVVRIQPGAEFRRVGPRHYELQPEHAADYERL
LDALANDGLRLAGILFFWGKRSRFESPDAEGLDDALGQGLYPLVRLIQALLPRRKDERIQLLYVYRSGGEEVIAHH---EALSGLARAVTAAAPWLNFRL
LGMDASGTTVERVLAELHASEAAT---QVEVRYRNGERHVRGVRPVPAHEAAAAMGPAFRQGGIYLITGGLGGVGYELAKYLAGKYRARLVLTGRSPL--
-EDELRRKLSHLEG----LGSDAVYVQADVVSRKDVDHCLAYVKA-RYSGLHGIIHCAGLLKEATLADKRQEDFGTTLAPKVQGTLVLDQATRAAPLELF
VVLSSVSTVIGTSLAADYATANRFLDSFAALRE-SRGQGQTSICYPYWRDGGMRMSPEKELVLQATGMEPLSSAQGIQALETALAL--------------
GHQQGL---------PQILTAFG------ELEKMQRALQAAPPP-------P--------AAAAATPPARPATP-----------PDASQAALEALVELA
VKTLRLQGTVNPRSELSGYGFESITILEFTQALNARYGTALSPALFYEHRTIEGYV----------------
>tr|K0UP11|K0UP11_MYCFO Polyketide synthase (Fragment) OS=Mycobacterium fortuitum subsp. fortuitum DSM 46621 GN=MFORT_24202 PE=4 SV=1
-----------------------------------------------------------------------------------------LPTTDAAAGQL
ENELRTAAASTLHILDIAAVDGEPTASSMRTLLRMQHQILAGTRRLFRAAADAGVKATIWLVTRGAQHVADADTVAPEQSALWGFGRAAALELPQLWGGL
ADLSEG----TTDEWTAVLNRVTTGRREDQIAVRDQAVYVPRLVRREDPNGT---PLELRSGATYLVTGGLGSIGLEIAGHLAAHGARHLVLTSRRDPSE
AAA------QRIAALSDQHGCDIRAVTADVADAHDVARLLSTVAA--EMPLAGIVHAAGELGTTPLSELDDAEVDRVFAGKVWGAWHLSEAAAEQKLDFF
ITTSSIASVWGGYGQTAYGAANAFLDGLAWRLR-EQKIPGTSVNFGPWA-TGMA-DAESRARLDQRGVRTLAPADALAGLADAVAVPAQGVVARIDWSRF
LP---LYQQAG------RRGFLA------EL-------------------------ETEAPAELTTASGKTQLVERLTNA--------PVQQRKKYLRDS
VAEVTRVDEIREDAGFFDLGMDSLMAVELRRRIEQGVGAEIPITLVMDHPRISDVSEYLLGD----------
>tr|X5KZ47|X5KZ47_9MYCO Polyketide synthase OS=Mycobacterium mageritense GN=BN978_03415 PE=4 SV=1
-----------------------------------------------------------------------------------------LPASDADEAQL
ADALRTAAASTLRILHVAALDTEG-APSMRSLLRMQHHVLAGTRRLFRATAAAELRAPTWLITRGAQHVTDADTVAPEQSALWGFGRAAALELPQVWGGL
ADLTDA----GADAWAGLLDRVAAATREDQIALRGHEVYVPRLVRREEPSGA---SLELRDDATYLVTGGLGSIGLEIAAYLAAHGAKHVVLTSRREPSD
AAA------QRIEALREQHGTDIRAVTADVADAHDVARLLAGVRA--DMPLAGIVHAAGEIGTTPLGELDSAEVDRVFAGKVWGAWNLSEAAADLKLDFF
INTSSIASVWGGFGQTAYSAANAFLDGLAWHLR-EQGVAGVSVNFGPWS-TGMA-DAESRRRLEQRGIRTLSPADALAGLADVVTARAQGVVARIDWARF
LP---LYQQAG------RRGFLT------EL-------------------------EREVPQSAATASGKTELVERLTNA--------PVQQRKKYLRDA
VADVTRVDEIREDAGFFDLGMDSLMAVELRRRLEQGVGHEIPVTLVMDHPRLSDAADYLLGD----------
>tr|A0A0J6VSH4|A0A0J6VSH4_9MYCO Erythronolide synthase, modules 3 and 4 OS=Mycobacterium chubuense GN=eryA_3 PE=4 SV=1
-----------------------------------------------------------------------------------------LPLSDAEEADV
ADAVRSAAAPALRIVHIAGLDADA-STSTRSLLRMQHRALPGTRRLFRAAATAEVRSPIWLVTRGAQRVADGDVTAPEQACLWGFGRAAALEAPQLWGGL
ADLAAG----TAEEWSALVQRIATGIRDDQIALRGHDGYVPRLIRRTGPNAQ---GPQIRSEATYLVTGGLGAIGLEIAGHLAAHGARHLVLTSRREPGE
AAR------QRIAALAEQHGCEVRVVAADVADAHDVARLLAMMHA--ELPLVGVVHAAGEIGTTPMTDLTDDEIDRVFAGKVWGAWHLAEAAAELNLDFF
VSTSSIASVWGGFGQTAYGAANAFLDGLSWRLR-ERGVAGSAVNFGPWA-VGMA-DARSRARLEERGVATLSPADALAGLADAMATAPQSVVARIDWARF
LP---LYEQTG------RRGLLA------EL-------------------------NQELPQAV-TASGRTALVERLTEA--------PVQQRRTYLRDA
VAEVTRVDEIREDAGFFDIGMDSLMAVELRRRIETGVGRDIPATLAMDHPRLLDVADYLLGE----------
>tr|X8E218|X8E218_9MYCO Malonyl CoA-acyl carrier protein transacylase OS=Mycobacterium abscessus subsp. bolletii 1513 GN=I540_0725 PE=4 SV=1
-----------------------------------------------------------------------------------------LPVSDADEAEL
VEALRSAADSALRIVHVAALAGQG-SSSTQSLLRIQHQVLGGTRRLFRAAAAAELRAPIWIVTRGAQHVIEGDTVAPEQSALWGFGRAAALELPQVWGGL
ADLSDA----GTDEWAQFIGRVSVSTREDQLALRGQAVHVPRLVRREEPSGK---PLEVRSDATYLVTGGLGSIGLEIAGYLAGRGAKHLVLTSRREPGE
AAR------QRIDALAA-QGCEVRAVTADVADGHDVARLLAGIQA--ELPLAGIVHAAGEIGTTPLSDLDDAEVDRVFAGKVWGAWHLSEAAAGLKLDFF
INTSSIAAVWGGYGQTAYSAANAFLDGLAWRLR-EQGIAGTSVNFGPWS-AGMA-DAESRARLEQRGIKTLSPTDALAGLADVVAAAVQGVIARIDWARF
LP---LYQQAG------KRGFLA------EL-------------------------DREVPSHLAAQSGSTQLVERLANA--------PVQQRKKYLRDA
VAEVTRVDEIREDAGFFDLGMDSLMAVELRRRMEQGVGKEIPVTLVMDHPRISDVADYLLGD----------
>tr|K0UC12|K0UC12_MYCVA Beta-ketoacyl synthase (Fragment) OS=Mycobacterium vaccae ATCC 25954 GN=MVAC_27309 PE=4 SV=1
-----------------------------------------------------------------------------------------LPMSEADEIKL
ADALRAAATPELRILHVAALDSDT-APSMRSLLRMQHRILGGTRRLFRAAAAAQLRTPIWLVTRGAQRVVDSDTVAPDQSALWGFGRAAALELPHLWGGL
VDLAG-C---TTEEWTGLLDRLAAAVREDQMALRDRTVYVPRLVRRTGPNLT---PLQLRSDATYLVTGGLGAIGLEIAGHLAAHGARHLVLTSRRAPGQ
AAQ------QRIDALREQHSCEIRVSATDVADAHAVARLLAEVAA--ELPLAGIVHAAGEIGTTALAEVDDAEVDRVFAGKVWGAWHLSEAAAELPLDFF
ISTSSIASVWGGYGQSSYGAANAFLDGMCWRLR-ELGIQGFSVNFGPWS-AGMA-DAQSRDRLAQRGIRTLSPADALAGLADATTSTAQTVVARIDWARF
LP---LYQQTG------RRGLLA------EL-------------------------DREVPDTS-TPSGTTPLVDRLTEA--------PVQQRRKYLRDA
VAEITRVDEIREDAGFFDLGMDSLMAVELRRRIEQGVGKEIPATLAMDHPRLSDVADYLLGE----------
>tr|L0IPH7|L0IPH7_MYCSM Polyketide synthase family protein OS=Mycobacterium smegmatis JS623 GN=Mycsm_00206 PE=4 SV=1
-----------------------------------------------------------------------------------------LPASDADGEKL
ADALHAAALSTLRIVHVAALDSST-APSMRSLLRMQHRILGGTRRLFRAAAAAELRRPIWVVTRSAQRATESDTVAPDQSCLWGFGRAASLELPHVWGGL
ADLSEG----TTEEWSRLINRITMEVIEDLIAVRGQAVYVPRLVRRDDLTGT---QLKVRSNATYLVTGGLGAIGLEIAGYLAAHGAQHLVLTSRGAPSE
AAQ------QRIDSLAEQYDCEIRVITADVGDAHGVARLLASVRA--ELPLTGIVHAAGEIGTTPLSDLDDAELDRVFAGKVWGAWHLSEAAADLQLDFF
ICTSSIASVWGGFGQTAYGAANAFLDGLAWRLR-EQGISGVSVNFGPWS-VGMA-DAESRARLDQRGVATLSPADALAGMANVVTASEQGVVARIDWARF
LP---LYQQAG------RRAFLA------EL-------------------------EREVPTQLTASGKKTQLVERLASA--------PVQQRKRYLRDA
VAEVTRVDEIREDAGFFDLGMDSLMAVELRRRLEQAVGREIPVTLVMDHPRLSDAADYLLGE----------
>tr|A0A024K197|A0A024K197_9MYCO Beta-ketoacyl synthase OS=Mycobacterium triplex GN=BN973_04061 PE=4 SV=1
-----------------------------------------------------------------------------------------LPASDADEEQL
AEALRAAAVSTLRIVHVAAVDAER-TPSMQSLLRMQHRILDGTRRLFRAAVAADLRAPIWLVTRGAQRVTDTDTVAPDQSCLWGFGRAASLEHPRLWGGL
ADLAEG----TADEWARFVDRISAAPREDQVALRDQSVYVPRLVRRSGPSVT---PLQLRTDATYLVTGGLGSVGLEIAGYLAAHGAGNLVLTSRRAPSE
AVQ------QRVDALAAQHGCDVRVFAADVADAHDVARLLARVRA--ELPLAGIVHAAGEIGTTALGNLDQAEVDRVFAGKVWGAWHLSEAAADLQLDFF
LSTSSIASVWGGYGQTAYGAANAFLDGLSWRLR-ERGVCGASVNFGPWA-AGMA-DAESRAKLDQRGIRTLSPADALAGLADVAASSAHGVVARVDWARF
LP---LYQQAG------RRAFLT------EL-------------------------AHEVPDA-VTPSGKTQLVERLTNA--------PLQQRKKYLRDA
VAEVTRVDEIREDAGFFDLGMDSLMAVEMRRRIEHGVGKEIPVTMVMDHPRLSDVADYLLGE----------
>tr|A0A064CKI8|A0A064CKI8_9MYCO Polyketide synthase OS=Mycobacterium aromaticivorans JS19b1 = JCM 16368 GN=Y900_014900 PE=4 SV=1
-----------------------------------------------------------------------------------------LPVSDADEERL
VAELTAAVQPALRILHLAALDSDG-SSSMRSLLRMQHRVLGGTQRLVRAAAAAELRSPIWVLTHNAQRVSDADTVAPEQSGLWGFCRVAALEYPQLWGGL
ADVSGT----GADEWTRLIKQVVTSPGEDQIALRDSGVHVPRLVRRTGPNST---PLELRSDATYLVTGGLGSIGLEIAGYLAAHGARQLVLTSRRASDE
AAQ------RRIDALSEQHGCAVRVVAADVADPHDVARLLATVAA--ELPLAGIVHAAGENSTTPLSSLDSTEIDRVFSGKVWGAWYLSEAAADLNLDFF
LSTSSISSVWGSYGQSAYSAANAFLDGLTWRLR-ERGVHGISVNFGPWS-AGMA-DQDARTQLDRRGIRTLSPTDALAGLADIMAAPAEAVVARMDWARF
LP---IYLQAG------RRSLMA------EV-------------------------AREVPESV-GASGTTRLVEQLTAA--------PVQQRKKYLRNT
VAEVTRVDEVREEAGFFDLGMDSLMAVELRRRLEQAVGKELPATLAMDFPRLTDVADYLLGE----------
>tr|A0A0P7IM86|A0A0P7IM86_9MYCO Polyketide synthase OS=Mycobacterium chimaera GN=AN931_07805 PE=4 SV=1
-----------------------------------------------------------------------------------------LPASDADEERL
AETLRAAATAALRIVHVAALEAGA-TPSMRSLLRMQHRILGGTRRVFRAAVAAELRSPIWIVTRGAQRVADTDTVAPHQSCLWGFGRAASLELPHVWGGL
ADLSEGGD-NAADEWSALVDRIAAAVREDQLALRDRAVYTPRLARRSAPSGT---PLHLRGDATYLVTGGLGAIGLEIAGYLAANGARHLVLTGRRDPSD
ATQ------QRINALGEQHGCQIRVVAADVADAHDVARLLASVQA--ELPLAGIVHAAGEIGTTPLSALQDAEVDRVFAGKVWGAWHLSEAAADLDLDFF
ISTSSIASVWGGFGQTAYGAANAFLDALAWRLR-GQGTLAVSVNFGPWS-AGMA-DAESRARLDQRGVRTLSPADALAGLADAVAALAQGVVARIDWARF
LP---LYQQAG------RRAFLA------EL-------------------------EREVPGLTGTVAGKTPLVERLTGA--------PVQQRKKYLRDA
VAEVTRVDEIREDAGFFDLGMDSLMAVELRRRIEQGVGKEIPATLAMDHPRLSDVADYLLRD----------
>tr|E6TLP1|E6TLP1_MYCSR Polyketide synthase family protein OS=Mycobacterium gilvum (strain DSM 45189 / LMG 24558 / Spyr1) GN=Mspyr1_03500 PE=4 SV=1
-----------------------------------------------------------------------------------------LPKSGAEEHEL
ADTLRDAAATDLRIVHVAALDAAE-DTSMKSLLRMQHRVLGGTRRLFGAAVAAQLRSPMWLVTRGAQHVTDTDVVAPDQTCLWGFGRAASLEHPQIWGGL
ADLGGG----TSDEWSRLLNRIAAAVMEDQVAVRGSTSYVPRLVHRDTPSGK---PLHLRADATYLVTGGLGSLGLEIAGYLAANGAGHLVLTSRRTPDE
AAA------SRIEALRERHGCEVRVVTADVADAHAVARLLATVQA--EMPLAGIVHAAGEIGTTPLADLDDAEVDRVFAGKVWGAWHLSEATSDLQLDFF
ISTSSIASVWGGFGQAAYGAANAFLDGLAWRLR-EQGVAGVSVNFGPWS-AGMA-DAQSRARLEQRGIKTLSPADALAGLSDAVIS-PHPVVARVDWSRF
LP---LYQQAG------RRGFLA------EL-------------------------ERELPAAPGTASGRTPLVERLTTA--------PLQQRKRYLRDA
VAEVTRVDEIREDAGFFDLGMDSLMAVELRRRIETGVGKEIPVTLVMDHPRLSDAADYLLGD----------
>tr|A0A0E2WEC4|A0A0E2WEC4_MYCAV Polyketide synthase OS=Mycobacterium avium subsp. hominissuis A5 GN=MAVA5_08350 PE=4 SV=1
-----------------------------------------------------------------------------------------LPASDADEERV
EIVLRAAAAAPLRIALVAALDSGT-APSMRSLLRMQHRVLAGTRRLFRAAAAAELRQPIWLVTRGAQRVTDADTVLPDQSCLWGFGRAASLEYPQLWGGL
ADLAQG----SAEEWSGLVRVASAAVGEDQIALRGSDIYVPRLTRRSGPAAA---ALTLRADATYLVTGGLGSIGLEIAGHLAAHGARHLVLTGRRAPGE
AAQ------RRIDALSQQHGCEVRVIAADVADAHHVARLLGTVRA--ELPVAGIVHAAGEIGTTPLSDLEDAEIDRVFAGKVWGAWHLSEAAADLRLDFF
VSTSSIASVWGGLGQTAYGAANAFLDGLAWRLR-EQGVNGISVNFGPWA-AGMA-DENARARLAQRGIKTLSPADALAGLADVMATAAQGVVARIDWTRF
LP---LYQQAG------QRSLLA------EL-------------------------AREVPDF-ATPSGKTGLVERLAGA--------PVQQRRKFLRNA
VAEVTRVDEIREDAGFFDLGMDSLMAIELRRHIEQGVGKQIPATLAMDYPRLSDVAEYLLGD----------
>tr|A0A0R3HZ45|A0A0R3HZ45_9MYCO Polyketide synthase OS=Mycobacterium sp. HXVII GN=AOT94_05035 PE=4 SV=1
-----------------------------------------------------------------------------------------LPTSDADEQQL
ADAFRSAVSSALRIVHVAALDG-G-TSSARSLLRIQHQILGGTRRLFRAAAAAELRAPIWVITRGAQRITETDTVAPEQSALWGFGRAAALELPQVWGGL
ADLADA----SAAEWSQFISRASAAAREDQIALRDQSVYVPRLVRRENPSGT---PLEIRDNGTYLVTGGLGSIGLEIAGYLAACGAKNLVLTSRREPNE
AAQ------QRIDALGAQHGCEVRVVTADVADAHDVARLLAGVQA--ELPLAGIVHAAGEIGTTPLSDLDDTEVDRVFAGKVWGAWHLSEAAADLKLDFF
ISTSSIASVWGGFGQTAYSAANAFLDGLAWRLR-EQGVAGTSVNFGPWT-AGMA-DAESRARLEQRGIKTLSPSDALAGLADVVAAGAQGVVARIDWARF
LP---LYQQAG------RRAFLA------EL-------------------------EREVPSHLQAQSGTTQLVERLAGA--------PVQQRKKYLRDA
VAEVTRVDEIREDAGFFDLGMDSLMAVELRQRMEQGVGKEIPVTLVMDHPRISDVADYLLGE----------
>tr|A1U9G3|A1U9G3_MYCSK Beta-ketoacyl synthase OS=Mycobacterium sp. (strain KMS) GN=Mkms_0254 PE=4 SV=1
-----------------------------------------------------------------------------------------SPVSDADEASL
ADALRASVDGAVRILHIAALDATT-APSMRTLLSMQHRILGRTRRLFHAVTTTGLRTPIWLITRGAQRVTATDTVAPDQSALWGFGRAASLELPHLWGGL
ADLPTGPG-ASEDEWSRLLDRIAADVTEDQVALRDGAVHVPRLVRRTGPSGA---PLRLRSDATYLVTGGLGAIGLEIAGYLAAHGAGNIVLTSRRAPGD
AAQ------QRIDALRDKFGCAIRVATADVADAHDVARLLAGVQA--ELPLAGIVHAAGEIGTTALSAMDQAEVDRVFAGKVWGAWHLSEAAVDLQLDFF
ISTSSIASVWGGFGQTAYGAANAFLDGLAWRLR-EQGIAATSVNFGPWS-AGMA-DAESRARLEQRGVRTLDPADALAGLADVVAGATQGVIARIDWARF
LP---LYQQAG------RRAFLT------EL-------------------------EREAPVASATASGKTPLVERLSGA--------PVQQRKKYLRDA
VAEVTRVDEIREDAGFFDLGMDSLMAVELRRRLEQGVGKEIPVTLVMDHPRLSDAADYLLGE----------
>tr|B6VN93|B6VN93_PHOAA Syringomycin synthetase OS=Photorhabdus asymbiotica subsp. asymbiotica (strain ATCC 43949 / 3105-77) GN=syrE PE=4 SV=1
--------------------NVAQWCRHPRWLPKPLDEAK-QNRAPWLIFGAQ---AAELSDLWEAAAGSIVVEDADEFQQQGTYRFSLRKDQLEDYQQL
IDCLIQQQLLPERIIWCWTAAVVPQPEAAEQLAAAI-----------KALTGHHRVFDITLISRGAARVL----EACHAAPALGLLGILAAEYPGCSARH
IDLDDNTFATHQSLIAELYDEATEGMPVTSIMLTQGKRELQTFAELDIPHRQ-----ILRDGGVYLITGGLGGIGQLLARYISNKCSAKLGILSRRETHP
ANEA-------FLDALRKSGAEVIILRADVADGVALTEALAQMRARFG-AINGVIHSAGIEASGLLEHSTSQDWRHVMAAKISGTQQLMTAIRQDSDFVL
LC-SSLASLIGGIGQADYAAANRYLDAVAHYWR-QQAIPVTSVNWDTWAEVGMAVNYAARRKE---------SVIGL-----------------------
-----------SNQEGCAIFDLAITG-----------MET--QVVVSKFTPVRRTQSRNLSA--------------IA------D----SASPEEAVRQL
WYELLGEETINLEDDFFELGGHSLLATQMISRLRDHFQHCLTLAEFLEQPTMARVV----------------
>tr|Q7N5R3|Q7N5R3_PHOLL Uncharacterized protein OS=Photorhabdus luminescens subsp. laumondii (strain TT01) GN=plu1880 PE=4 SV=1
--------------------NVARWCRYPRWLPKPLGEAK-QNRAPWLIFGAQ---AAELSDLSQAAAGSIVVEDADEFLQQSTYRFSLRKDQPEDYQRL
IDCLIQQQVLPERIIWCWTAAGISQPEAAEQLAAAI-----------KALTGHHRVFNITLISRGAAKVL----EACNAAPALGLLGILAAEYPGCSARH
IDLNDDTFATYQSLIAELYEETTEGIPVTSISLKQGERELQTFTELDIPRRQ-----ILRDGGVYLITGGLGGIGQLLARHISNQCSVKLGILSRRGTNA
VSEA-------LLDVLQKSGAEVMMLRADVADDAALTKALAQMRARFG-AINGVIHSAGIEASGLLEHGTSQDWRHVMAAKVSGTQQLMTAISQDPDFVL
LC-SSLASLVGGMGQADYAAANRYLDAVAHYWR-QQAIPVTSVNWDTWAEVGMAVDYAARRQE---------SVIGL-----------------------
-----------SNQEGCAIFDLAIAG-----------MEA--QIVVNKFPPVQRTQLQDLSV--------------IS------D----SASPEEAVRQL
WYELLGEETIHLEDDFFELGGHSLLATQMISRLRDHFQHCLTLAEFLEQPTMARVV----------------
>tr|A0A074L6W7|A0A074L6W7_PAEPO Uncharacterized protein OS=Paenibacillus polymyxa GN=EL23_24325 PE=4 SV=1
-------------------------YYQPLWREC-LPNSDGGVPEQVIVFGTDTGLWNSLKK---RGIKAVLVQPGDAYRSVQGDIYEIDPLNPKHYEML
FSTIKQNQQTAEALIYAWSD--QRFVSEKEELQTELERGIYSLFYLSKALMRESLRCKLLYVYQG-----SGQ---PQNAAVSGFARTLRKENPALIYAT
VELSESAETSLDQL----LSEFSVDDEEVEIRYQQFVRYMSLINELGTS------SISLREKGTYMITGGLGGLGSIFAGYLASKYKARLVIAGRSP---
LTSEHEQKI----KQWERCGASVLYVQADISLREQCIAMIAKAKE-RFGHIHGVIHAAGVLRDAYILRKSIDQIEEVLAAKLYGTVWLDEATRHEELDFF
LMFSSIMSVIGNAGQCDYAYANAFMDYYAHHRTEGRSGKSLLINWPLWKEGGMTVDAPLAFMENTMGILPISTEEGIRAFEDALH-------MSGD----
--QMIVLK--E-NPSKKI--------------KLFNST-SSIKEKFSAKG--------QLSES-----DEQMIYR------G----------LCEDIRMI
TSDILDKDTIEMDTDYSEYGFDSISTTDFINRVNQKFHLELTPPVFYEFVNMGSFVSYLK------------
>tr|A0A0Q4QU18|A0A0Q4QU18_9BACL Uncharacterized protein OS=Paenibacillus sp. Leaf72 GN=ASF12_16660 PE=4 SV=1
----------------------NALYYTMKWMEEAADQLTRAMRGETVII---LGEWQQLTQQLEEEGHCIQVKRGTHYQVVSPQSYMI-SENEEDYDKL
TEALK--HVKFTKILHLLCCNGPDGMMSAEQLSERQSLGVYSLFHLTKALLN--AGVEIIIAADYVNRVTGEETLKPENSPLFGLGKVIGIEYPHITCKA
IDMD--ALTTARDVISELG----RNKTTYQIAYRDGKRFAEIMEETDVEQLPDDPVS-IKEEGVYVITGGAGNLGLLTAKHLASKGKINVALLNRSPLSR
LHD----TIKKLHEIAA-TGAQVECISLNVTSLDEMSATMERLRQTYG-KINGVIHAAGVAGRGFLIRKDTAVFEEVLNPKVMGTWVLDKVTEQDDLDFF
VLFSSGVALVGEMGQGDYTAANCYLDAFADYRR-KLGKPALSINWVVWDGARMGEGTSIDSIF-----KTLPATLALQGFDKVISKA---------ITRV
LIGEVNTS----NPSG--LELFS----KDVFH-LPEKLRAIMFSDSSSEQAVQSKPLPMQEVK-------------VKLLGSK---NGSYSEVEQTLAGL
YREVLGYEELSINDTFFELGGDSVQLHRLHKLVDQRYTGQTSIADLFAYASIAKLASFLTKE----------
>tr|S9UUF1|S9UUF1_PAEAL Beta-ketoacyl synthase OS=Paenibacillus alvei A6-6i-x GN=PAAL66ix_05009 PE=4 SV=1
----------------------PDLFYEMEWFQDQVQQHTNSLTGETILI---LGTWDALTERLREEGNCIQVIPGDEYQIVSDRTYVI-GKREEDYANF
IQHVVQSEIHITKVIHLFTLNRNRLITNLDELDEVQNDGVRSLFHLTKALLN--SRMEIFIVSDYVNKVTGKEKIKPENAPLFGLGKVIGIEYPHLQCRA
IDLD--ESASVHDLLSEIK----TNRYTYQIALRNGIRFAEMMTESRIEAANERDVS-IKEDGVYVITGGTGKLGLQMAKHLASKGKINLALINRSCFAP
LSE----KIELLTEIQS-RGAHVECLALDIASMIEVSHTFERLRQKYG-RINGIIHAAGVAGRGFLIGKNQTVFDEVLHAKVYGTWVLDKVTEKDNLDFF
VLFSSGVALSGELGQGDYTAANCYLDAYAEHRS-LIGKSTLSINWVVWKGARMEEGNSIDSIF-----KAIPIHQALQAFDKVLNKD---------ISRV
LIGELNPA----PTEN--LELFS----NKVFH-LSDRIQNVLNRSEG--KLREISPMATSKPD-------------IKLTGNE---AGDYTDIEKKLALL
YREVLGYNELNTNDSFFELGGDSVQLHRLHKLMEQEYPGRVAIADLFTYSSISRLAAFIKQN----------
>tr|B2IYP4|B2IYP4_NOSP7 Beta-ketoacyl synthase OS=Nostoc punctiforme (strain ATCC 29133 / PCC 73102) GN=Npun_F3169 PE=4 SV=1
--------------------NLQDWLYQITWQLQGRTITQSSLVQYWILLIDEDAVGTELAKLFQAKGSCVAVIPSYTYQSLEQGKIYINPAEPQHFDRL
LQEVSIQPGIALHIVHLWSLATGD-L-----LDSTQMRICGSVLHLTQALARINFP--LARLWLISRGSQSILQSEIAQTPLWGLGRVIATEYSEVFAGL
IDLDPQSST--VEAATQLWAEFSHPELGEQVALRGNQRYVSRLQRVPNTIDF--SASFNPSLGTYLITGGLGGLGLTVANWLVERGVQHLVLVGRRSPSD
K---AKSAIASWEN----AGVQVTVTQADITQLEQIQKILEGIEPQ--FPLRGVIHAAGILDDGILLQQNWERFTRVMAPKLQGAWNLHILTQDKPLELF
VLFSSVASVLGTTGQANYAAANAFLDGLADYRR-FQGLAGLSINWGAWAEVGMATGSPV-------GVEKILPQQGLQI-LAALTHQANAAVLPVRWSKF
IAHYYTQ---------KVPPLLS------E----------FVDSRQTQEQPVLAYILRQLQE--------AHTADIQ-------------QILFNYIRDE
VAKILRFNSLQLRQRLFEVGLDSLMAIELRNRLQSSLECSLPTTLLFDYPTLETLTKYLTND----------
>tr|A0A0N0D6X1|A0A0N0D6X1_9DELT Short-chain dehydrogenase OS=Candidatus Magnetomorum sp. HK-1 GN=MHK_001061 PE=4 SV=1
--------------------NTENLFYSIEWEKREISRPTD---SSYLIFSDEKGTGNQLSQYLARKNSHLQVSKN-----------NLNHDFSQNFIRL
FETFEQNNDSEFNILFLRGLTDDD-SVE--IMRKKINNLYENLLSFVQSVINKWKH--LPRIWLITRNAWNIQMHQIEQTGIWGIGRVIALEHTDMWGGC
IDLDNCESD--NWVEAL-LTAVSSIANNDQIAVRNNSLYVARLKGAPIPSNK--ENQFVKSDATYLVTGGLGALGLRTAERLFHCGAKNIVLLGRSTPEK
G---AKKRIEALKQ----EGVRIEIFQADVSDETVMAEVFNSIQKNM-PPLLGIVHAAGVLDDGILIKQNPMRFNEVLSPKIFGSWNLHLLTKDIPLDFF
VMFSSSSAITGNQGQGNYAAANAFMNGLAYYRR-TKGLVATSISWGPWAGIGMATNIQDK-----VGLRLIPMETGLEI-FENLIG-VNISVMDLDVNVF
TARNYLE---------KT-DFFS------N----------YIRSKSLSEEKTKYELVNKLKN--------APFEART-------------ENMISFLLEI
TKQ--VIGNIISDRPIMDMGFDSLMIMELRNRISSELGKKLPVSILFDYPTLDSLANHLIQN----------
>tr|E1UUN3|E1UUN3_BACAS Bacillaene synthesis polyketide synthase of type I OS=Bacillus amyloliquefaciens (strain ATCC 23350 / DSM 7 / BCRC 11601 / NBRC
---------------EENAGAGVPVSAEPVWKEQQKPAQEHPSYEQHIIFLCEYDEA--VK------QAIEAKLEHASVFILDERPASIAERYHSYAGQL
FDHI-------K-------------TIMKGKP-----KGRILLQAVTRSAGL--QQ--------------------VF-SGITGLFRTACLEHSKLIFQM
IEAD--EKESAEDIAEKVSENHMHAESVHV-KYENGKRFAADWEEVDIQAEP---DIPWKDEGVYLITGGAGGLGLIFAKEIANRKDAVIILTGR---SA
LGEKQQDLLETV----RAAGASVFYEQTDVTDEAEVYRFIRNIRKRHG-KLDGIVHSAGIIKDNYMVKKPAEEYQDVLAPKVKGLVYLDEASQHEKDVFI
-VFSSLSGVLGSVGQADYASANVFMEMYAAYRRSLRYGKTLSVSWPLWKEGGMQAGKQTEILMQEAGIAPLSTEAGIKALYQGLMSGAVRVTVLE-----
-------------------GDVK--NMK---AKLFRK----ENDHPEAESGVHHEI------------DADSLLEKVK----------------HLLKQQ
TASLLKLDKIDAHEEMTKYGLDSISMTEFTNQLNKTYRLRLTPTIFFDHPTIHEFAVHLISE----------
>tr|F1TDH7|F1TDH7_9FIRM AMP-dependent synthetase and ligase OS=[Clostridium] papyrosolvens DSM 2782 GN=Cpap_1809 PE=4 SV=1
---------------NAIKHEEPPVRDKKIWCKAELNISGKQEVENVLVFDTDNELA--LML----GQQYKTVMPGENFLQLDERTFKICAGKKDDENDI
YDDSNISKFLTQ-------------ALLSQKI-----EGIVKLLYYQEGTSFT-AP--------------------FD-SAISGFVKTLYKENPNYIFKC
IGLD--EIKASQNLVRLA-INEFNNEDFEI-RYKENERKVKALQTVEVTKNG---ILPIKKEGIYLITGGLGGVGMIFAEYFAKEYNATLILTGR---SP
LDEKTSLKLEKL----KLSSNKIIYIQSDISDKAQVVELNESIMGKYG-SVNGVIHAAGQLKDSFIIKKNSKEIAEVLSSKIFGTLNLHKTFNSSNDFFV
-LFSSVSAEEGLIGQADYAYANSFMDNFAQ-----SCSNVISINWGLWNNGGMKMGGHNAQMSSKNGMLEISADEGITMFSSALTMKEASIVATV-----
-------------------KDLG--NTT---QDLIKK----TKSDSS-D--NQLST------------GSDKVQELAW----------------NYFANL
ISEETPLKEISLKEPFRTFGIDSIMSLNMVEKLEKSFGL-LSKTLFYENQTIEELIAYFIKN----------
>tr|H2JGN3|H2JGN3_9CLOT Amino acid adenylation enzyme/thioester reductase family protein OS=Clostridium sp. BNL1100 GN=Clo1100_2633 PE=4 SV=1
--------------------EISEWFFVPSWRRANLSYSNKHTLKNILVFINYTEFSNNLVRSLESAVKLTFVKIGTSFCQDKESGYFINPGKNTDYKNL
FNELHKSENIPDTILYLWTLTE--DNLHQPKVNTAFDIGFYGLIYIAQAIGELNIPISINVVTNNMHLVSGEENINPEKAVIVGPIRTIPKEYSNIKCTG
IDIEVPQEDKTKETINCLLAEMAITDNDSLVAYRGKYRWIQSFNQIQLKECHGVPSR-LRENGVYVITGGLGGIGLAISEYLAGTVRARLVLIGRTEIPP
REN-WDDYINSPEKELEELGAEVLPINADVSDNYQMSKAMSTIHERFG-EVNGIIHSAGLPDGGLIQLRNRKTTDSIMSSKIQGTLEVNRFIEHNKDFMI
YCSSLSSIIAP-FGQIGYCSANNFQDAFSQHQC-NKGYYTVSINWDTWKQVGMAVNLTCNGILISEGIEV------FKRILD---SDLPDYLL-------
-AQVLI-----SPYPLEVY--LK---------RIWD----TERE--------QYK----IKSEENYNPEECMNLQ----------DITSQSEIESKLTAI
LKEILGYPDIGRDDNFFDLGAYSLHLIQLRQRLKAVLNIDISIVSLYANTTISSLSRYLSKR----------
>tr|F1TBP2|F1TBP2_9FIRM Acyl transferase OS=[Clostridium] papyrosolvens DSM 2782 GN=Cpap_2599 PE=4 SV=1
-----------------------------------------------------------LEEYLRHKGTVVRVKKGLFYNAEA-YGYTINYSNSEDYEKL
MQDIYKSGEKFRGVIHIP-LHERNELLGSEL---NTDSGVFVHMYLAKAILA--AKISLKLITFNGLAVPADKSVVPESALLVGLDRNIPYEVKNISSLA
IDFNRNISN--EDFANKLIYELSFRSKFKEISYRNNERFIRITREFEGNINE---TGCSTDGGVYLITGGLSGLGAIFAEYFIRNNAEAVYLTGRRDIKE
LTDSKASELEKLNNINIKNNTAIEYRKSDVSNPESLDSVVK-EITSKYGRITGIVHCAGLVDSVTLRTKTYESFAKTISPKFQGTMNIGRAFMNILDFMI
LSSISGLNGKLGATLCDYAAANFYMNEYAKALAQNSGKKVVSVSWPLWEGVGLGAKKAYGGESSDMGLKIFDA----------V-----------IKSKN
CGNLIV---------------LNTDKSDFSLNGLFKEEETL-----TFEKAADMKT-------------------------SDVDKAASRESLKEYLKGL
LVEFIEVSQISEYTNFSEYGIDSVIVADIVAVIERKYKIFLHPSIILEYPTINALADFLMEE----------
>tr|H8MFK7|H8MFK7_CORCM Malonyl CoA-acyl carrier protein transacylase OS=Corallococcus coralloides (strain ATCC 25202 / DSM 2259 / NBRC 100086 / M2) GN=ppsE6 PE=4 SV=1
--------------------DVADWFYAPSWKLSPLPKA-KDAAGKWLVLADDTGVAEALAPKLG--GDVFRVVPGARFEQRPDGTFTVDPARREDFCSV
LEALKKQGRAFSNVVHLWGLSHEP-----ASQEKALDLGFHSQLFLARALSETGHLEPLTWSVVTSRSARVEQAQLPEQALLVGPSRVLPQEYPNLSCRF
VDMVP--SD-AGAVVDRLAAELGAEPRDAVVALRGRQRWVQTFEPVRLEAAG---AEVLRDGGAYLITDGLTGIGHALASELATVHQAKLTLVETPDQDA
VSRRIQ------RALALERTGVMLVLPASLTDVESMRGVVD-AAVARFGQIDGVIHAAGGMQGATLAETGPDECAWHFRPQVHGVRVLEEVLPKEGPAFC
LLVSSLSSVLGGLGQVAQASASAFMDAFAEA-R-TEGFAWLSVDWDAWQAQAMAELSP---TLAQF---AIQPAEGLEALRRALSHGESAVSTGD-----
---------------------L------------------AARRRQ-GPRAA---K------AEKGKKDAAKGHARPSI---LTPYAAPRTELEKTVAGI
WEQVLGIDGIGINDNFFELGGHSLLATQLRNHIHAVLKVDLSLRGLFETPTVAGVAG---------------
>tr|R4K3I5|R4K3I5_CLOPA Polyketide synthase family protein OS=Clostridium pasteurianum BC1 GN=Clopa_1305 PE=4 SV=1
---------------------ADKWFYKWQWQEEVNIPQEKIEEGAVIIFNDPKGIGSELSKFSEAVNPVYFVEAGEEFKYDGKNNFVINPSKKDDYDNI
IKNLSH---KLSLIIHLWNLPYSEEAITSSKDNFL-YESLYSVFNIAQAVKA-EVKNNISFIVVTDRAQLINHAPHQS--LAAVLAQAIDEDNTNINSQI
IDIDIKEYINTLEIGDKLFIEFNKKVDPGISVIRDNKSFVRKLERFK-ASGDKLK---INQGETYLITGGTSPLGGDLAKELAKQANINLILTGRSALPE
VSNEIKEKINLIL-DLEKLGAKVLYASVDVTNKAEMEKLVSKINDQYG-NIQGVVHAAGVLDYSSLLNKNVDILKKVFAPKVQGTVITDLVTRKEPLKFF
ISSVSASKKKWSQGLGEYAAANSFLNAYTNYRN-SIGAKTIAINYSLWDNKGMGAGESTASAIKAQGLKPLSPEKAAKAFIEAIAVKESNIHI-IDLLKE
NIVEKVQN--TDR-----------------SEQV----------TAAEHREVSYLEAKEVKNTVY---------QVI---GKQ--------------LEI
P-----AEELDIGTNFLELGLDSLGAIKVIEKLSKALKVELYPTIIFEYQTPEALGNYIEN-----------
>tr|A0A0H3J6A9|A0A0H3J6A9_CLOPA Erythronolide synthase, modules 5 and 6 OS=Clostridium pasteurianum DSM 525 = ATCC 6013 GN=eryA PE=4 SV=1
---------------------ADRWFYRWHWQEAAEIPEKKIDPGAVIIFSDSKGIGNEISRFNQERNPIYFVEAGEEFKYEGKNKFIVNPDKKEDYINI
IKNLPH---NLSAIIHLWNLPYSEEDLVLSKDKLL-QESVYSIFNIAQAAKA-EREENINLIVVTDRAQLINDTPHQS--IAAVLAQSIDEDNTDITSKI
VDIDINEYVSAVEAADRLFHEFNSKSDSRISVIRENKSFIRKLDTFK-PSIEKVK---INSGETYLITGGTSSLGGDLAKELAKQANINLILTGRTALPK
CSEDIREKINLIC-DLEKLGAEVMYVSVDVTDKDKMKDLINAIDNKYG-SIQGVIHAAGVLDHSSLLNKNTEILKKVFAPKFQGTIITDLVTRKEPLKFF
ISSVSASKKKWSQGLGEYAAANSYLNAYSNYRN-GIGAKTIVVNYSLWDNKGMGAGETAGNAVKAQGLKPLSPKKAAQIFIEAISVSESNVHV-MDLIKE
SIVKKPEN--KI------------------IEDI----------ALSTAEEVSYLAVKEVKEIVY---------KII---GEQ--------------LDI
S-----VDELDIGMNFLELGMDSVGAIKVIEKLSKELKVQLYPTIIFEYQTPETLANHIEK-----------
>tr|A0A0F4Q905|A0A0F4Q905_PSEO7 Thioester reductase OS=Pseudoalteromonas piscicida GN=TW73_06115 PE=4 SV=1
------------------------------------------------LIMDSHGVAEELASQMLNGHTVYRAYSAEGFNRLDDQSFNIDIGNSQDYETL
LEVINK-EVQLDRVVHLLGVTATENMLSMTQFNQAQRYGAYSALYTVQAIVKLDDKLSIDFITNDVERVTGDETLNIGKSTIKGLCKVAPQEYPELSCHH
IDVHLNQA--TRDHAIRLSLELHSQQRAPLVALRGNQRWEPDYETELIDTET-PAAHRLVDGGVYFITGGLGNIGLLLANYISQAVAPKLVLVGRSEFPE
LEPKQIEQIT----QVEKSGAEVLILSADSANLQQMQDAMNVVESQFG-AISGVIHAAGQLHGSMTAETTEDDFEKQYCAKANGVIVLETLLQKRQVDFC
ILMSSLSSVLGGLGFSAYAAGNQFMDAFVQSKHEQGDERWVSVNWDGWSFTEATQD-----------DFSMTPEEGVEAFAA-MMS--------------
---IAYHPQ-------L------VNSTGALEKRLSQWIDKKVTESQQ---------------------------ALYERPDLESDYIAPRNEVEEKLVAI
WQQVLGIEQIGIEDNFFDLGGDSLVVTRVISEIRKIFSVALSIKEFFEKPIISQLSEKIAAE----------
>tr|A0A0Q4QU18|A0A0Q4QU18_9BACL Uncharacterized protein OS=Paenibacillus sp. Leaf72 GN=ASF12_16660 PE=4 SV=1
-----------------------------------------PAAGVTVIVKDSEGFADRLASALRDQGRQVLLAEIPDLSATE-EMGEIEAKWLDRYSQL
LQEEAEQGIA--QIIHCGSLAGSV-ISSIDELKASQQRGAMSLFLLMKAWAAFEHDTEVIVLTENACRITGEEQLRPENAPLLGLAKALSKEHANIRCRS
IDMDGE------VQLEEILSELSINSDARLVAFRNGIRYVELFEPCSLNESS-SEELTVQAGGVYLITGGTGGIGLETAKWLSRKGRIKLVLINRSELPD
LNNKLCEKIASIREIEA-GGSEVILYRCDVSQYDETAAMLEHIRLTHG-EIKGIVHGAGIARTESIMEKSLDTFEQVIRAKIYGTWLLDQLTLQDQDFFL
MYSSIATMFETG-YQSDYLAANAYLDAYSMAPS-SDGRRRLTINWTTWQGKGMASDHNF-------QADTIFKARAME-LLDAVW-------------QT
RQNVLIGELNLE-SRMALWLNYA----IQLSDDIT-ASLDALNERLAQTP------ERS---SK------SAGYAAVKLIGSEHD---AFSETERQVAQT
CKGVLGFSEIDIHESFFEMGADSLMIRQIYQKLSQLYTEEVVITDMFEYPTVHKLAKHIERR----------
>tr|S9UUF1|S9UUF1_PAEAL Beta-ketoacyl synthase OS=Paenibacillus alvei A6-6i-x GN=PAAL66ix_05009 PE=4 SV=1
-----------------------------------------KTSGAVVILTNDGEWSKQLIERIELSGKVVL--KIPVFRKNM-PLAYDEHAYLHDMEGL
LTGFHASGIS--QIIHCGSLMMGK-VATLNDLEVSQQQGSLSLFLLMKAWLKFEHDVEVVLVSEYVYTVTGKEKCRPENAPLFGLGKALSKEHPNVKCRI
IDIDES------TGIENLLDEMNEGNDSNVVALRNGQRYEPTFEEYFLDSSE-QEYCSVQPGGVYIITGGTGSIGLDTANLLATKGRIKLVLVNRSLFPD
ASGKLCDKIRMIRLIES-KGSDVILYRTDISKVDQLTIMLNEIRSQFG-EIKGIVHGAGLTKVEPLTEKSIDTFQEVMSSKVYGTWLLDHMTSTDKDFFL
MYSSIATWFETG-FQSDYIAANAYIDSYSAMSS-PDGRKRMVINWTTWKDKGMASDNRF-------QIDTIFKTKAIE-ILEQVW-------------NQ
PIQLLIGEINYE-SSMALWLNYS----YHLSEQIV-QKLSCVQHRMNSER------EDA---RE------NSIINRVNLIGSHSD---ISGQTAQTIAEI
CREVLGFMDIDIHESFFEMGADSLHMKQFFQKLNKYYPGKALITDLFEYPTIYKLSQYIDQQ----------
>tr|B8I5H3|B8I5H3_CLOCE Beta-ketoacyl synthase OS=Clostridium cellulolyticum (strain ATCC 35319 / DSM 5812 / JCM 6584 / H10) GN=Ccel_2376 PE=4 SV=1
------------------------------------------------IFMDAEGIGEGLASNLTDKGDVIQVMLGESYEKKNELSYTI-SGCERDYYKL
FEDMGDRRIS--KIIHLFGNRSKQYGDSPEELELSHITGVYSLFYMVKSFAKLKSGVEMVLVSRNTFSVDKQEKANPGNAALFALGRVISAEYENIRCRG
VDIDTD-TD-----ANSLVSEVYGYNTSYLTAIRDGKRYIQEFARLEMGG-GSRKGIDIKSQGVYIITGGLGGIGLEIARHLSQKGAGNIALVNRSSMPE
LKAKLCQRINAINSIEADGTAVFSYP-GDISVKDQMMGVINEIRD-KFNNINGIIHCAGLAGEGLISGKSQADLSKVLSPKIEGTFMLDNVTREDEIDFF
VTFSSVMSILNVPGQGDYAAANAFMDSFAQWRS-TQGKRTVSISWPAWKDTGMAAEYKANKSL----FKPISVEQALSDFELILESESTHVIAGLDF---
---EMLSGISED------IQLFK------LEK----DIAAELESTVSSNSSVKESPLPTVKL-----------------KG---GVSGNYTKLEKLIGNI
WGAILEIGELSIHDDFYDLGGNSLLSINMASKLKEQLNVEIDINNLFEHFSIVDLAMFISEK----------
>tr|I2C4I6|I2C4I6_BACAM Polyketide synthase type I OS=Bacillus amyloliquefaciens Y2 GN=mlnE PE=4 SV=1
-------------------------------------------------------MKRQLEGY---EAPFIYVTSGERFEDCRNGRFTMNFTKGEDYDAL
CGVLRSQNIRPRHIIHFLAAGLFK---NTEDAMRKQLNKSLYSLFMFQAANKLCPKAEILYLYE---NTEGEVQPIY--NAVESFLKTVQAENPNFTCKA
AELKFDEPFTKQHIADVISFEWNNKTDHF-TCY----------EPRHYYKRQRVKKHSVKKNGVYLITGGAGGLGYLFAEYLAKQAEVKLVLTGRSPASS
---ETAQKLSALEN----LGAEALYVPADISKEKETDALIKHIKQTFG-ELNGILHSAGLVKDAFIIKKTKESIEEVIAPKVFGTVWLDKAAEEEPLDFF
VMFSSLSAVLPNAGQSDYAFANGCMDGFTQYRSKGRPGKTLSINWPLWDAGNMTVGPGELQALRHAGLELLSAQAGLAAFQDSMSRSASQLA-VISGDKD
RISELLSTDH----------------KEI----------------------------ETVPENNSNLPQL-NEKDL-----------------KKQTVRL
LTEIVGADSILPEDTFDRYGIDSLTILGLNSRLEKYF-GRVSKTLFFEYSSVEELSEYFLEH----------
>tr|W4BAM4|W4BAM4_9BACL Beta-ketoacyl synthase family protein,phosphopantetheine-containing protein OS=Paenibacillus sp. FSL R5-192 GN=C161_02755 PE=4 
--------------------------YELVWQQKGIAKGDSISDGTTLVLLDGSDYAAEIAARMESGMQVYSVL-------QT-DVLRSDPDSVEAYERV
LQQ---VGLDLSRIVYLNGVGSEEHSASMESLESVLNERVYGFFRFIRALLSSSQPIELVLISREVNSITERMKPH--LASAFGMGRVVGKENIQIHCRC
IDIDEG------SSLDLLLKEIGTSSSYYEVAYRNGTRYVQEFRALNESAPP-EDELVFDNDGVYIITGGTGGIGLETARYLASDAPVNLALISRTPMPA
REAEQSHQITVIREL-ESRGHQVSCHAADVSDLDAMRVLLDQLRVTFG-KIKGIVHGAGVGSSEMITSRSQAGFTEVFSPKVHGTWVLDQLTEQDHLDFM
VLYIASVFSAPGQ--ADYIAANAYLDAYADYRS-MMGKRTLTVQWSTWKETGMSAEFAVDTLFK-----AMPTEQAMNQLSLVMRSSVRRVLIGQIEGQL
ISALAK-------------SPFD----------LSSSIRVQLDQRMKQLASKRLP--ASSSEDRDGEV----------VLTGK--SDASYTPTEKALATI
CKTMLGFHEINVGDSFFEMGADSIVLIQVQARIDQQFPGLTKVTDLFANSNITRLARFMDEK----------
>tr|A0A0Q4QSK7|A0A0Q4QSK7_9BACL Uncharacterized protein OS=Paenibacillus sp. Leaf72 GN=ASF12_16670 PE=4 SV=1
--------------------------YGGQWVRQEQLMAE-QQAGPVLIFMDEKGLGQSLAAEWNRGTKTVQVY-------LRKQYAKLDDGSVDDYVLL
LKD---NKGTWSKIIHLFSIVPE----GWNSFNETQYRGVYSLFYLSKAVAQVSAVTDTVIISDYVDVVRERVNPW--NAPLLALGKSARQELPSMLCRA
IDIDEA------TSLDTIIREIGAAPSYYMVAFRDNERYAEIFKEYRVQEAN-EQPIEVKEEGIYLITGGTGGMGIETAKYLAARKKVNIALINRTPLPD
KADRNSQRIKAVREI-EAMGAHVECYSLDIANMQQMEELVGGLRARYG-RINGIVHGAGVGGDGFLYLKEEQVFNEVVHPKVFGTWILDKLTEQDRPDFF
LMFMSSRFAVPGQ--GDYCAANTFLDAFAKYKT-LNQQKALSINWVAWKETGMAVEVNADGAFK-----ALPTAVAMRGLDEALNRSVSNVLIGELGSDL
LWELGL-------------VPQL----------LDSPIDAAITGSQKRWEARQLA----SQRRFEGEI----------KLTGK---DGDYTDLETKLAEI
YCQVLGFNEIDMDDNFFELGGDSILLGRVHASLEKHYPGKVRLLDLFEYTSVSKLQQYMRED----------
>tr|A0A0L7ZFR4|A0A0L7ZFR4_VIBAL Uncharacterized protein OS=Vibrio alginolyticus GN=ACS86_00615 PE=4 SV=1
-----------------RRLALPTYAFQKHWIEAPKQAQKAETASHWLIFSDGAGFGAVLAHLLEERGSVVCVEQGSAFSQNGAYQFTVKAGASDDIDRV
LSTLKRQNWFPDHLAYMWPLDQQAASDCSSQLEWCEQHALMDIQAITRLGRALVDCYLLTHRGAIASDAALG--HGSQ-VALSALCQVIAQEDPLFQIHQ
IDLDQP---SLDDVAMSLLLDLYAKEKPPRVAYRDGVRMVPELV--RLPTDT---TPFSLSSGTYVITGGLGRIGLSLAAQLAMACPCHLVLLTRQDFTD
LSDEMKVTLRQLQALERE-GVTVSVLQSDVTDLAQLRGTLDAVTQEFG-AIKGIIHCAGQV-EGLSTQITAADLAAQALPKMAGARNLQTVCQDVPVEFV
VLMSSISTVLGGLGYSAYAAANAWMDSLAFSERHNEVTRWRTINWDTWLF-DS-----SQGAQHGNGIPGMDPSEGLAVIEAALNQSEPLIYAAGD----
-----------------------------VEARLAKWVHRQSREAQ-----------------SVGTVA--------ASSTQAS--SLPR-AHEASLRDI
WHELLGVEHIGPEDTFFDLGGDSLLATRLVSLIRQRCGVEVSIEQIYQSADFAGLATLLEAG----------
>tr|Q08PV2|Q08PV2_STIAD Uncharacterized protein (Fragment) OS=Stigmatella aurantiaca (strain DW4/3-1) GN=STIAU_0242 PE=4 SV=1
-----------------------EWLYTLEWKRHEGAEHGPEGTGAWLVLSDTTGTGQSLAELMQARGRCVLVTAADRYAQLGPGRFQVNAAAPEDYRRV
LKDFGEAG-GCRGLIHLWSLDTGG----LEDLEPAQRLGSQSALYLAQAVVR-EGGRDTPRLWLVTQGASQGERVSVAQAPLWGFGRALSLEHPELQTTL
VDVVAD---APRAQAQALWAEMGAADGETQIAWRQGTRSVARLVRGTYDTGA--VLPSLHANATYLITGGLGGLGLTLAKWMVTRGARHLVLVGRGEP-S
PTA--RTVLRELE----EAGATVVVERADVANRAQMAGVLGRI-HHEQHPLKGLVHAAAVLDDGTMLELDAERFHRPMNAKGHGAWNLHTLTAGWELDFF
VMYSSAASLLGFPGQSNYAAANAFMDALAWHRR-GQGLPGLSINWGAFAEVGMAAQSNRGERLRHRGVGSLKPEQGTAVLERLLAGSSAQVAV-------
-------MQLEARQWLEFYPNAS----APLWTVLLAEQAK--------TK-SREST-----------------SVRFREALSKAEPSQRGALVEEHLAEQ
IALVLEPSKIDRLRALGELGLDSLMSLELRNRLEAALGMKLSATLLFTYPNLASLAQHVVGR----------
>tr|A0A0A0NG10|A0A0A0NG10_9ACTN Uncharacterized protein OS=Streptomyces rapamycinicus NRRL 5491 GN=M271_08650 PE=4 SV=1
----------------------------------------------------------------------------------------LAGPDSELARAL
THRLERRGIRVRRQLTLWLAGPAAECPTVADLDAATH-TVLSTL--LDLIPSMGQGGG--RLLAVTEDVHGATTLCPAQALLTGLALALPEEFPRLTAYG
VDLSSYDSL--GARLDALEREAFAPG-GGAVAWRAGRRLVRIPVAVATDAAP--ASSPLPPDGTYLITGGAGGLGAALARDLAGRGQPTLVLAGRSACPP
NSL-----MTEL----DALGVTAAYRVADVSVEADVEALVGDL-----PPLDGVFHAAGVVRPGTLRTKSLEEMAEVMAAKVRGSHLLSRAL-WRHPAVC
VAFSSVTSVLPGLALGDYAAANAFLDAFAASER-ATGRPWQSLNFAAFAETGLAAGAPSTVPAMTRGVAPLPPGAGLAALHAACGIDAAQLVVA-ETTAE
LSAEMTAEMTAEMTAESATVRPG----AAVSGTAGLSEHVASATRRSGTS-VSVPPGDPSPTTAPGSPAPA---------PATGTADPAPAHITGVLCRL
LAEALHRSPAEIGDQFLTMGLDSLSAVDLVRRLESELGRALPPTLFFEYRTIGELATHLSTDQ---------
>tr|A0A0R3RGQ9|A0A0R3RGQ9_9BILA Uncharacterized protein OS=Elaeophora elaphi PE=4 SV=1
--------------------------YEPCWVPCKLTT-RRRLPKGVLLFVPSTKAVDALIMLHNLFIPVQCIFSDALSTGNTNDKIYINSNKEESYHHL
ANFLRNTNFYYDTVIHAWNFSSYESGRIN-------DSYLLPSFYSIYWILTSIMQNDLRFLVIIDWNAIPEIF------TVLGPIRELTMTRQFVQAAC
LLCTLEVNLFEALQL---FESY-QTDFSLIRNLIGEFEYFSY-----QLKSFEWNDCLIRSSDVVVIF-GFGNISQSFINVLCQNFDFTICIASPNATCH
FEKNRWKSSRKFKISDTQEEHIIRAYDVDITKEDHLNELMLQY-----GRINIIIHAAAGKAASIKFAKSFDQMQFVLQPKIRGIRNVIDILYENRSFIL
NSSMNA--LFGLPGNSDYAASNIFLDSC-CRGNFRNIENITSVQWSGWKDSNMLNT-----------------------------------YN-GNRSQN
PVANLIIEHSLLVQEAE------------------RMIWKCL--HERGLIAVSFSPNDIVHEIRKLNFNTNGKFVTVPEQESVKRN---CDDLRNIIAKI
WMNYLGVEQITCHDDFFQLGGHSLNGMQIIWEINRVMEIDCKLDDLFQNSQFENFLQFLQRLDV--------
>tr|J0DYR9|J0DYR9_LOALO Uncharacterized protein OS=Loa loa GN=LOAG_17563 PE=4 SV=1
--------------------------YESCWIPYKFTN-RRRLPKGILLFLPITKPINTLTILHNLFVPVRCIFSDTLSSGNINGNVYINSNNEESYQQL
ASFLRNGDFHYDTIIHAWNFPNHETERTN-------DSYLLSSFYSIYWILANVIQNDLRLLVSIDWDAEPELF------TVLGPIRELAMTKRSMKAAC
ILCTPEVNLFEGLQL---LESY-PADFLLIRNSIGEFEHFSY-----KLKPIEENDCLVQSADVVVIF-GFGNIGQSFVTVLCQNFDFTIYLVSPNATRH
FQQNQWKTSRKFKMSVINDQHTIHAYDVDITKKEDLTQIMSQH-----GRINVIIHAAAGKIDSTKFEKNFNEIQSIFQPKIRGIRNIIDTLHGNRSLIL
NSSMNA--LFGLPGNTDYAASNIFLDACCCRRNFRNIQNITTIQWTGWKDSNMLGY-----------------------------------YMNENKSQN
PVTDLIIEYSLSLEEAG------------------QMIWKCF--HERGLIAVSSVPNDIIREIRKLNFMTSRKFGIIPEQKTVEKN---CNDLRNIIAKI
WMDNLGVEQVTYHDDFFQLGGHSLNGMQIIWEINRMLQINCKLDDLFQNSKFENFLKFLQKFVI--------
>tr|A0A0B2VT50|A0A0B2VT50_TOXCA Linear gramicidin synthase subunit B OS=Toxocara canis GN=lgrB PE=4 SV=1
--------------------------FRRCWIDIPKLL--ATTLKCVLLFLPLSNSLQQLVDFKNRFIKYICVQPNRNRD--CDDVLQINPAQEIGYQEL
ANHLRMLRFQCSLVVHAWNVADFEN-LSV-------DQKLEQSFYSVLWIKRYFSD-ALNIIAVVDDSAPAEVF------TILGPIRELHTTKPLSYGIC
LSVSCDADLCSLIHQL-HFSSW-KPEFCYVRYDGNKLQEMNF-----CETVV-SNDYLLHDGDVVVVLGGCGSVGQAFVRFFCKKLKSTVILASRIATQR
CEE-------TLQ--TFGGQHQFVAYDVDLGNAKEIKQLLQKY-----SHIDLIVHAAGQAT-TTRLEKTREDVETVFASKIYGTRNLLSALDNNGGLIM
TSSLSA--ILGIHGSEDYAAANIFLDEVSNR--FCSIDKLISIEWCAWKSSTMIAG-----------------------------------YTS--S-YD
EIAQLIKTNSLSDHECE------------------RLFFDAL--QHTGCMAISTAPIVIVKEIERIQKRHSVVV---DS-VSQPIA---VSTIENITTQI
WEECLGVKNISLQDNFFQLGGHSLNALQITWQINKRLGFASTVNDLFKYPILGDFLAILQNKRK--------
>tr|A0A044S6I2|A0A044S6I2_ONCVO Uncharacterized protein OS=Onchocerca volvulus GN=WBGene00238648 PE=4 SV=1
--------------------------YEPCWIPCKFSTQKQQLPKGVLLFLPFTKSINALTMLHNLFIPVQCIFSDIVSSENVNENIYINSNKEESYQQL
ANYLHTINFHYDTIIHAWNLSNEIFDRID-------NSFLFSSFYSIYWILANVTQNDLRFLVCIDWNSEPEIF------TVLGPIRELAMTGQLTQTAC
ILCTSEVNLFEALQL---LESL-QANFAFIRNSVNEFEHFSY-----QLKAIRKNDCLIRNADIIVIF-GFGNIGQSFINVLCQNFDFTIYVVSPNATRH
FQENQWKVSRKSGKAFQSGNHTILAYDVDVTKEDELMQIMLQH-----GRINVIIHAAAAKIDNIKFEKSFDEIEFVLQPKVRGTRNIINTLHQNRNLIL
NSSMNA--LFGLPGNNDYAASNIFLDAC-CRRNFRNIHNITTIQWTGWKASNMFNY-----------------------------------YSMENKSLN
PVANLIVEYSLSVQDAE------------------RMIWKCL--HEQGLIAVSSVPSDIAREIHKLNFTINRKFTNIPEGSQIEKN---STDLRNTVAKI
WMNYLGVEQVTDQGDFIQLGGHSLNGMQIIWEINRMMKINCKLDDLFKNSRFGNFLQFLQQLII--------
>tr|A0A0N5D2U7|A0A0N5D2U7_THECL Uncharacterized protein OS=Thelazia callipaeda PE=4 SV=1
--------------------------YQPCWVPINFTSQSIWNSKGVLIFAPPNKSINELVVLRNLFIPYFCVLNANLSSDSTDSNTYISDLTEKSYKQL
ADILCDQNFHFDTIIHAWNFCENAC-LYK-------EPTLLSSFYSIRWIIQNIVSTILRFLILIGQDSEAESY------TALNPIRELIMMQNSVHCTS
LLCKSEVNLFKALQL---LESF-QPDFSLIRNLVDQYEYFSY-----FLKLFH-QNCLIQNHDIIVIFGGFGRIGQSFLKVLCQNFKANIYSSSPNATRH
FLQHEWQNGN------NCDEHKIIANDVDISKYVELQNIIAKY-----GRIDVIIHAAASRNHPNVFEKNFSQIESILQPKINGTRNVLKVLSENRSLIL
NSSMNA--LFGLPGNSDYAASNSFLDAL-CDQKFCNIQNITSIQWMGWKGSQMLEE-----------------------------------YAI--QTQN
PVANLIMQNSILQDNAE------------------ELILNCL--HERGLVAVSFVPNEIIKEFRKLNFRNSEKKKL----KDEEVN---CNDLKNFISKI
WMDCLAVENITDSDDFFQLGGHSLNGMQIIWEINRVTKINLKLDNLLKNSKFKDFLHYLQRINA--------
>tr|A0A0M3JX13|A0A0M3JX13_ANISI Uncharacterized protein OS=Anisakis simplex PE=4 SV=1
--------------------------FRRCWVGLQKLPSRSTPLKSVLLFMPMNGTLKQIIDLKNLFIECVHVEPIEAAVRNTNGILTIDPSQENAYQQL
GDHLRRANFKCSLVIHAWNMRDFEN-LSV-------AQRLYISFYSHLWIKRYLSDIHLSVISLVQARAPPEAL------TLLGPIRELHMTQLQSYALC
LQISDGVDLCNHILHL-RQSIW-KPKFCYLRCDANRLQEMSF-----CESVH-ADSHLFHENDLILIFGGCGSLGQAFIKFLTRQYRSTFVIVSRNARNI
FGQ-------KIQ--SQDGGHCFDVYDIDMSDAPKIRNLNEKY-----QRINVVINAAGQVT-SKQLHKSGRDVERVFASKIYGTRNIFDALQSNRGVLL
TSTLSS--ILGINGNEDYAAANVFLDELAEFSYRSVTDNVISVQWSGWKDSTMIAE-----------------------------------YAS--DANS
QVAKLIIDNSLSDLQYE------------------RVFFNAV--QYRGCNAVSTVPAEIVDQVARLQKQPLSFT---EPQIAATTH---LKLNEEMVKEI
WKQCLGVETISMKDNFFHLGGHSLNGMQITWQINKQLGHNFTINDLFKHPVLADFLELLSSNKN--------
>tr|G2NX71|G2NX71_STRVO Beta-ketoacyl synthase OS=Streptomyces violaceusniger Tu 4113 GN=Strvi_8003 PE=4 SV=1
-------------------SAVDGWRYRVSWKPVTERSAAGVLGGCWVVVVPVDGAGGVWRMLAGRGVDVRVVESDA-----------------ADRAGI
ADELRAADASVTGVVSLLAVGDAS-----------V-TDVLRTAALVQALGDAGVGAPLWVATRGAVSGRSDGVVSPGQALVWGLGRVAALELPERWGGL
VDLPESVDER---VLGRLAGVLAGVGGEDQVAVRGSGVFGRRLVRAASSGSAASEGSWSPGAGSVLVTGGTGALGAYLARWLVENGAEHVVLTSRRGLDA
PGA------VELRDELAASGARVTVAACDVADRDALAELLAGLPE--ELPLTAVVHAAGVLDDGVLDSLTPERFASVLRAKADAARHLDELTRDLDLTAF
VLFSSITGSVGAAGQGNYAAANAYLDALAELRR-AEGLPATSIAWGPWAGSGMAGDDAMERRMRREGMPPMAPESAVAALRQALDVDDTAVVADIDWEN-
---------------------FTRTLTAVRPSPLIAEAEAGPRAATGAESG---------KVVTDA-DSATP---LGERLSGLPKG-EQDRALLELVRTQ
VASVLGAEAVEAGRAFKELGFDSLAAIELRNRLNAATGLRLAATLIYDYPNATALADHLRTE----------
>tr|G4XIM8|G4XIM8_9ACTN Polyketide synthase type I OS=Nocardiopsis sp. FU40 GN=apoS6 PE=4 SV=1
-------------------LPAAGLEYTAAWRRGDEVFAE---AADAFGLHPALLDSALHTGVTLFASSALRVQAPV-----------------ASGFA-
----LRPLEISDRDTVLLECVSA--------------AANSEVLRSVQSASARFADSRLVVVTRGAVADPAEDVPDLAAAAVWGLLRSAQAEHPGRFVL-
LDLDRGDASY-----RAVPA----ASDEPQLAVRDGEVRVPRLARVASPDLAVPSPAFSS-DRTVLVTGATGGLGRLIARHLVTHGVRHLLLASRRGMAA
PGA------DELAAELGRWGARVTMAACDVANPDEVARLLAAVPE--DHPLGAVVHAAGALDDGVLEALDPSRMAAVSRPKADAAWNLHTFTRDL--DAF
VLFSSAAGTLGSPGQGNYAAANAFLDALAQHRR-AQGLPAVSLAWGAWAE-GMSEDASGRARLVRGGMRPLSEQDGLALFDAALGSDRAVLPMALDLGA-
---------------------VLRESGGTVP-AVFRG-----RTPV---RR---------T-ARSA-GSGTP---LAGRLAGLSAD-EQDRAMRTLVREQ
VARVLGAEHVELAKAFQDMGFDSLTALELRNRLNEATGLRLNATLIFDYPTPLTLAQHLREQ----------
>tr|C5HV18|C5HV18_STRAT Polyketide synthase OS=Streptomyces antibioticus GN=idmP PE=4 SV=1
-------------------SVVDSWRYRVGWRPAQIS---TTPTGTWLVIAPAAHQEHPWESLRDGGAEVRTVVDPT-----------------ALQDSL
AQEL---GAQIDGVLSLLALDETP-----------LPAGLGATLTLLQALGDAGIEAPLWCATQGAVSSGVDHLTRPLQAQVWGLGRVAGLEHPDRWGGL
VDLPETVDAR---SAGRLRALLAEPGDEDQLALRPSGAFVRRLTRAPLEDTP-PVREWRP-DGTTLITGGTGGLGGHVARWLAAQGAGHLVLTSRRGPDA
DGA------AELREELQGMGSRVSIVACDASDRNALGALLRRLRDE-GTPVRAVVHTAGVAGRFTLADADLADLAETLGAKAGGAAALDELLAGGEPDAF
VLFSSNAGVWGGAGQGPYAAANAYLDALAEQRR-ARGAAATSVAWGMWSGQGLVAQPGVEEALRRLGLKAMDPDLAITALHQALDRDETTLVTDMDWDR-
---------------------FVSVFTAARPRPLLDEAARILRAAEAG-------------HEANS-ESRSA---LAEQLAGLAPA-EQHRLLVEMVRAQ
AATVLGGDAVDQDRQFQELGFNSVSAVELRNRLNEATGLRLPASLVFDHPTPAALARRIRAE----------
>tr|X5IBU4|X5IBU4_9ACTN Type I polyketide synthase OS=Streptomyces sp. MJ635-86F5 GN=cmiP5 PE=4 SV=1
-------------------SATDGWRYRSTWKPLSDGAMGDLAGDRWMVVHASGAADAEPRALAARGAHVVAVETAA-----------------TDRG--
--HLTARGAPIAGVVSLLAFAEGA-----------QPAALAQTLLLIQALGDAEVGAPLWLVTRGAVAVSSDE-ADPVQAQIWGLGRAAALEHSRRWGGM
IDLPTTLGER---TAARLAAVLTRDHGEDQVAVREAGVLGRRLVRAARDD--VRATPWRP-RGTVLITGGTGALGGHVARRLARNGAGHLVLTGRRGLGA
PGA------ADLRDELVASGAEVTIASCDAGDRSQLAQLVRSLADR-GNPVRAVVHAAGVDSARELSLMALDELADTLRAKAGGAAHLDALF-DDDLDAF
VLFSSVAGIWGGAGQGAYAAANASLDALAERRR-GRGLAATAVAWGPWAEAGMAAQGDDEELLRRQGLPPMEPDHAVTALERAVAEGVATVVADVAWNR-
---------------------FAAGFTAGRPSPLIGDVQQTLAGTPDAQFG-------------DV-PAATE---IGRRLAGLDPA-EQHSVVLELVCRQ
AALVLGPDAIETGRAFRDLGFDSLSAVELRNRLAESTGLRLPTTMVFDYPTPVGLADRLLAE----------
>tr|J1RVE2|J1RVE2_9ACTN Acyl transferase (Fragment) OS=Streptomyces auratus AGR0001 GN=SU9_33608 PE=4 SV=1
-------------------AQADSWRYRITWKPVPAGAAPATLRGTWLVVTGGAHTP---TALSAAGAHPVLVPDAE-----------------ADRTAL
AGTIDAALPPVAGVVSLLALDEDE-----------HHRGFAATVALVQALDDTGVEAPLWFATRGAVADPQRGVTAPRQALVWGFGRVVALEQPERWGGL
LDLPETLDPA---AATAVVRALAGIGDEDQLAIRPHGVLARRLVRAATGELD-TTRRWTP-QGTVLVTGGTGALGRHVARWLAQNGAAHLLLVSRRGAET
PGT------DELAAELAEFGTHTEFAACDIADRDALADLLDTIPA--DRPLTAVLHTAAVLDDATINSLTPAQLAGVLRVKAGGARNLDELTRPRGLSAF
VLFSSTAGTIGAPGHANYAPGNAYLDALAQQRR-AAGHRATSIAWGPWAEAGMAEGT-VGERLHRHGVRVMDPRSAVAALQRALDHDDTTLVTDIDWDT-
---------------------FTHAYTTARPRPLIADAQRARATAAP--------------ATEET-TEGPA---LARRLAALGEA-EQRQALSELVRAH
VAAVLNPDEVAPHRAFRELGFDSLMAVELRNALSTAIGTRLPATLIFDHPTPAALATRLRTE----------
>tr|R1HJ52|R1HJ52_9PSEU Beta-ketoacyl synthase (Fragment) OS=Amycolatopsis vancoresmycina DSM 44592 GN=H480_36228 PE=4 SV=1
-------------------STVDAWRYRVEWKPLAEPEA-VTLSGRWAVVAPAGTDTTELSCLTAAGAEPVVLEPGG-----------------GLTAEL
ANGLADSLPAVAGVISLLPD-------------------APGTLLLTQALD--GSTAPLWLLTRNAVALPGDTPPAADPAQVWALGRVVGLEHPERWGGL
VDLPATLDRR---ATRRLAAVLAGLDHEDQVALRASGLFARRLAHAPGAE---PRRNWRP-RGTVLVTGGTGALGRHVARWLARAGAEHLVLVSRRGADA
PGA------AELEAE---LGTRVTFAACDLADRDAVAALVERLGD-----VRAVVHTAGLPQAQTIDGTSVADFAEILAAKAAGADHLDELLGD-DLDAF
VLFSSNAGVWGSAGQGAYAAANAHLDALAARRR-AAGRPATAVAWGSWAGDGMAGSAEAKEHLRRRGLREMAPERAIAALQQALDADETFVVADMDWAR-
---------------------FAAGFTAARRRPLIEDVRAGEEVV--------------------T-EVGTG---LAEAVRGLGPR-EAAHHVLELVRAQ
AAAVLGGAAVPADRAFRDLGFDSLTAVELRNRLTAATGVRLPSTVVFDHPHPRALAGLLLDE----------
>tr|R1G5I0|R1G5I0_9PSEU Beta-ketoacyl synthase (Fragment) OS=Amycolatopsis vancoresmycina DSM 44592 GN=H480_20135 PE=4 SV=1
-------------------AEATGVDYRAVWTRGSDVFAELRGEAARFGLHPALLDAALHSGVSLAASTVLRVATPV-----------------SADVA-
----LRT------FEVFR--VPD--------------GSVTAVLARLQEGGP---DGLLVVHTTGAV-ADGEDVTDLAAAAVTGLVRSAQTENPGRFVL-
LDAGEVP------------A----PLGEPQLALRSGTWRAPRLARASIVD----NTPDWG-DGAVLITGASGLLGGLVARHLVTHGVRRLLLLSRREPA-
----------DLAHELAGLGATATAVACDVADRARLAEVLA------GHHVSAVVHAAGVLDDGVLESLTPDRLAAVLRPKAEAALNLHELTTDL--SAF
VLFSSFAATTGGAGQAGYAAANAFLDALAQHRR-AHGLPAVALAWGLWAEASMGHADGDRRRMAGAGMTPLDTEFGLALFDRAVAADRAVLPVRLELAA-
---------------------LRRQP--VTP-TLFHG-----PPAR---RQ-----------ATAA-AAQTS---FADRLAALGED-DRVRQVLDLVREL
VAGVLGGAAVEPARAFKELGFDSLTALELRNRLAAETGLRLPATLVFDHPTPQALTRYVVER----------
>tr|A0A0D0H907|A0A0D0H907_9BURK KY49.ctg7180000000020_quiver, whole genome shotgun sequence OS=Burkholderia sp. MSHR3999 GN=KY49_5846 PE=4 SV=1
-------------------FDEGGML-REVTEPQAWLD--FGLTPGWWSFTDPLLDAAQWPALATPEAESVIVAKA------------------------
AARAESGRAPLERVTEIYAWRAAA-----------DP---REPLALCQALP-RWRELQASFVTAGAQP--AGGVTEPLQALLWGHLPAFVNEN-ARFARI
VDVDRDEP-V---GPALLGAL---QRDECQIAVRRDAWFVPRLRAATLVE---AGAPVVSGDASYLITGGFGALGIETARALAAQGARHLLLLGRRVPAS
AEA--------ALAGLREQGVAVHALVADVGDETALRAALASVPPE-APPLRGVVHSVGVLDDGVVGQQSWERYLRVLRPKMAGALLLHRLLDACALDFF
VLYSSAAGLMGNPGQANHAAASAFLDAFAWYLR-GQGVPAVALDWGAWSEIGAA-ARDVGARLGAEGAGVIAPEQGAAVIARQFGCANTQLVLPLNLRQ-
---------------------PVDASRQPQVRRLLAEDAAAAGMRAVDAGD---------GEGEAA-EAGDA---WLARLLRMSVR-ERRRHLGDYLAQT
AGALLKPGAIDAQASLFDQGLDSLLAIDLRGTLERRFGQRFESTLLFDQPSVAALTDFLLGA----------
>tr|Q0B308|Q0B308_BURCM Beta-ketoacyl synthase OS=Burkholderia ambifaria (strain ATCC BAA-244 / AMMD) GN=Bamb_5920 PE=4 SV=1
-------------------FEEGGML-REVTEPQAWLD--FGLTPGWWGFADPLLDAAQWPALATAEAESVIVART------------------------
AASADSGRAPLERVDELYAWRPTV-----------DP---REPLALCQALP-RWRQLEASFLTAGAQA--AGRVSEPLQALLWGHLPAFVNEN-ARFARI
IDVDRDEP-A---GAALLGAL---QREDCQIAVRGEAGFVPRLRRAALVE---AGAPVVSAEASYLVTGGFGALGIETARALAAQGARHLLLLGRRLPPS
AEV--------ALAGLREQGVAVHTLLADVGDEASLRAALAGVPAE-LPPLRGVVHSVGVLDDGVIGQQSWARYQRVLHPKLGGALLLHRLLAPRPLDFF
VLYSSAAGLMGNPGQANHAAASAFLDAFAWYLR-GRGVPAVALDWGAWSEIGAA-ARDVGARLGAEGAGVIAPEQGAAVMARQFGCANTQLVLPLKLNQ-
---------------------PIDASRQPQVRRLLAEEAAGGATQATGVTG---------GAAADA-EAGDA---WLDRLLRVSTR-ERRRELGEYLEQT
AGSLLRPGAIDGQASLFDQGLDSLLAIDLRGTLERRFEQRFESTLLFDHPSVAALTEFLLGA----------
>tr|A0A0A8EKB8|A0A0A8EKB8_9ACTN Acyl transferase OS=Streptomyces sp. 769 GN=GZL_03712 PE=4 SV=1
-------------------AAAESWWYRVVWRPAAEPAA-AALTGSWLVLVPAALAEDELAALTGHGAEVVLLPADT-----------------D--ADL
TERLRTVDGAPNGVLSLLSRDGRL-----------WP-----NVVAAQALGEAKVDAPLWCVTQDAVAGRSDRLRNADQAQIWGFGRVFGLEHPQRWGGL
VDLPELVDDR---TLARLVGVLARRGGEDQFAVREGGVFARRLEHAGG----RAAQSWQP-RGTVLITGGTGALGTELARWLAANGAEHLVLAGRRGPDA
PGA------AELAAE---LGDQVTIAACDVADRTALAALLGSIPA--ERPLTAVVHAAGVLDDGLLTALTPDRVEAVLRPKVDAARALHELTADLELDAF
VLCSSVAGVWGNGGQAAYAAANAFLDALAQQRR-AAGLPATSIALGLLAGGGLAEAG--EQHQRRLGLRPMAPGTVASALAQAVCRNESALLADVDWST-
---------------------FVPAMGAVRPLSLVDEARMLPAA------------------------EKVE---LRDWLEGLSEA-EQQRLLLELVRSQ
VAAVLGSQGIDASRAFRELGFDSLTGVDFRNRLGAATGLTLPATLVFDHPTPMVLVDFLRGE----------
>sp|Q03133|ERYA3_SACER Erythronolide synthase, modules 5 and 6 OS=Saccharopolyspora erythraea GN=eryA PE=1 SV=4
-------------------DEDDDWRYQVVWREAEWESA--SLAGRVLLVTGP-GVPSELSGLEQSGATVLTCDESR-----------------ST---I
GTAL---TDALSTVGVAAVPHGEA-----------V-DPSLDALALVQALGAAGVEAPLWVLTRNAVQADG-ELVDPAQAMVGGLGRVVGIEQPGRWGGL
VDLVDA-DAA---SIRSLAAVLADPRGEEQVAIRADGIKVARLVPAPARA---RTHPLEPLAGTVLVTGGTGGIGAHLARWLARSGAEHLVLLGRRGADA
PGA------SELREELTALGTGVTIAACDVADRARLEAVLAAAAAE-GRTVSAVMHAAGVSTSTPLDDLTEAEFTEIADVKVRGTVNLDELCP--DLDAF
VLFSSNAGVWGSPGLASYAAANAFLDGFARAAR-SEGAPVTSIAWGLWAGQNMAGEG--GEYLRSQGLRAMDPDRAVEELHITLDHGQTSVVVDMDRRR-
---------------------FVELFTAARHRPLFDEARAEARQ---------------------S-EEGPA---LAQRLAALLDG-REREHLAHLIRAE
VAAVLGDAAIDRDRAFRDLGFDSMTAVDLRNRLAAVTGVREAATVVFDHPTITRLADHYLER----------
>tr|A0A060ZVD9|A0A060ZVD9_9ACTN Type I polyketide synthase OS=Streptomyces iranensis GN=SIRAN6351 PE=4 SV=1
-------------------STVDGWRYRVTWKPLPDGQ-PARLTGAWLVVAPD--TEDTWGVLAERGADVRRIADTA-----------------ADGDEL
AERLRAAGIPFTGVLSLLALDGRS-----------HPAGVAAQLALVQALGDAEVGAPLWSATQGAVSGRADPLDSPEQALVWGLGRVAALEHGERWGGL
VDLPGAPDER---ALARLVTVLAGAEEEDQVAIRATGLLVRRLVRAPLAATP-AVRAWKP-TGTTLVTGGTGALGAHVARWLAGNGAEHLVLTSRRGLDA
PGA------ADLRSELTELGAKVTIAACDVADRAQVEALLADIPA--EHPLTAVVHTAAVLDDGVIEGLTPDQVDRVLKVKVDATRHLHELTRDLDLSAF
VLFSSFAATFGAPGQGNYAPGNAFLDAFAEHRR-AQGLPATSLAWGPWGEGGMAEGG-VGDRMRRHGVIEMAPRAAVTALQHALDRDESVLVVDMEWKR-
---------------------FVLAFTSGRSRPLLHDARDVIQDM----AG---------EVEADG-AGAVA---LAQQLAGVPEA-EQERLVLELVRTA
VAAVLGADDVEAGRAFKELGFDSLTAVELRNRLSAASGLKLPPTLIFDYPTPTVLARQLRTE----------
>tr|K7QQB6|K7QQB6_9ACTN PyrA5 OS=Streptomyces rugosporus GN=pyrA5 PE=4 SV=1
-------------------LDLRGYEYRAVWRSEGVLFAEVADAGGF-AVHPALLDGALHSAVSVHGPPVLRVREPE-----------------GA-V--
----TRPQVSVTAVTILLPCESSA-----------DPERAEHVLAVVQEADERYADTTLAVVTRGAVAGEEDVLD-LPHAPIWGLIRVAQAENPGRLV-L
IDLDTSRDAA---GLALN-AAL--ASGEPQLAIRKGVLHAPRLTRVRPTSSP-SPLELDE-DGVVLVTGGTGLLGGLVAEHLASYGMRHVLRLGRAGG--
----------------------EGAVACDVSDRQAVQELLAS---L-DRPVTAVVHCAGLLDDATVQNLTPEAVRTVFAPKVDGAWHLHELVG--GTAAF
VLFSSAAGTLGNPGQANYAAANTFLDALAAHRR-AQGRPAVSLAWGPWEGGLTDKTEADRARVRHNWITPFTAETGLAAFDTAFDTA-------------
---------------------FNGGF-NGVLVPLRLDIRAAATIHPMLRES---------GQKPPA-SGRDA---LIRELSGRAVP-EQEHLVLELVRER
TAAVLGGAAVDPQRPFRELGFDSLTAVDLRNQLGAATGLRLPATLIFDYPTAALLAAHLRTE----------
>tr|H0KBG1|H0KBG1_9PSEU Beta-ketoacyl synthase (Fragment) OS=Saccharomonospora azurea SZMC 14600 GN=SZMC14600_22378 PE=4 SV=1
-------------------IDAEGLEYRAAWRLGDDVYTEEHAEAERCGLHPALLDAALHSGVTIVAALRVRVRTSV-----------------GTDVS-
----LRA------ITVFE--AAG--------------SDPSTVLDRVQDADSSDGDARLVVVTRGAVAEPGEPVRDVPAAGVWGLVRSVQAEHPDRVVI-
VDVDDDPRST-----DLLGA----ASGEPQAAVRGGEVFVARLGRASAQLVASLPQPLNP-DGTVLITGGTGSLGGLVARRLV-QGVRRLVLLSRRGVAS
PEL------LESLA-----PAEVSVVACDAADREALSGVIA---G--IETLTAVVHTAGVLDDGVVESMTAQRIETVMAPKALAAWNLHELTRDHDVAEF
VLFSSASGVFGNAGQANYSAANTFLDGLAAHRR-ALGLPGLSLAWGLWDQQGMAGADTDKARTSRSGSSALRPDQGLALFEATRKRPDAVLPAPLDPTA-
---------------------LR---DDTVP-PLLRA-----QRSL---RR---------AASRKA-GGDGS---LAHKLAGLPVA-EQDKQLTDLVRAN
AAIVLGPERIEPRQAFKDLGFDSLTSVELRNRLAAAVGTKLPATLIFDYPNPDALGTYLRTE----------
>tr|A0A0L6JGW4|A0A0L6JGW4_9FIRM 6-deoxyerythronolide-B synthase, Phenylalanine racemase (ATP-hydrolyzing) OS=Pseudobacteroides cellulosolvens ATCC 35603 = DSM 2933 GN=Bccel_0225 PE=4 SV=1
--------------------HFQNLYYSAVWRKRKPQQAKNEAKEGSTIVLKGVGEKEIVKRLRQCRKDIIEVKLGEGFQSLNDGNFIID-GSLESFKRL
LSKLKDRNIS--QVIHLCTAQGSVEIKDVIEIDESQKKGVYNLLYLSQAISSREEPIDLVVISEKVYEITGMEQIYPQNATLFGLGKVVRLENPMLKCRC
IDIDRE-T--GI---DTILIEINYPSDEYLTAYRNGDRYTQEIGHADLSRLDD-DEIEVKNDGVYIITGGTGRLGLKIAQWLASQNKVNIALLNRTHFPR
VDPELCQRIEAIQKI-ESTGTAITLCSTDVTEITELNSTLSKLRECYGK-INGIIHCAGIGVGILLKDEQRETFENILAPKVYGTWLLENLTKDDNPDFL
ILFSSAITITGGVGAGSYTTANTYLDSFVLKAK-KYFKKVLSINWTTWESVLRFAGVKID---KDRLIFIIPDDTALKAFDI-------VVHKK--INNV
IIGEMNI--GSSIFDIKPYMPFTLSQDT--------------QS--------------EIKQNRT-QIKLDSFSDALPELTGKAENE-SYTEMEDRIARV
WGKVLGIGEINIYDSFFDLGGHSVLAVKLEVEM-GKAGMPVEGADIYKYQTIKDMASYLGTK----------
>tr|A0A075R541|A0A075R541_BRELA PKS domain-containing protein OS=Brevibacillus laterosporus LMG 15441 GN=BRLA_c026500 PE=4 SV=1
-----------------NKAKNASFYYGLDWIEKEINLTDSKDMGTVLIFKDETSIGDQMRQAFDSMDPWIQVEWGAEFEELDQRSYKIN-GLQSDYMTL
IGLLKERGI--TQIVHLLSVVEKQDVNDLLDLEETQKRGYESLVRLTKALLEHNDEIEILLVAPYVYELNEQQEIQPHHATLFGLGKVVTQEYPHLLCRA
IDIDKW------TTAETILAELGSKDKDYLVMHRKDQRFVEEFCEWNLDDIA-DDSIEIRENGVYLLTGGLGAIGLEMAHYLASQASVNLVLINRSSLPS
REEQSQRQITAI-RQIEALGSHVTVLSADISDQDELQAVLAQV-RSQFTRINGIIHSAGVAGEGFILRKEEASSQQVLSPKVKGTWLLDHLTKGDQLDFM
VLFSSINSLYGGVGQGDYVAANAYLDAFTSYRN-RHTGKTLTINWAAWKEVGMAVEY---GANRDVGFFSLSAIQAFQQVLHKQLKR------------V
TIA-----------------EINYDNTP---EHL-----DALSFHLANPIKTKLEKMERLKDRRQRAVASQGLPD-ITLLGRNAS--ESYSTNERLVAQV
FCLELGLDEINIYDDFFSLGGDSIIAVKIVNSVQKHLNKNIGISEIFQN-----------------------
>tr|A0A0M8VN55|A0A0M8VN55_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. AS58 GN=ADL00_12465 PE=4 SV=1
------------------------------------------------------------------GEQVVTVTAGTAYERTAEDAFLMRPEAAEDYEQL
VDALQKDGPRTWNVLYLWDVKAD------ASLEQAQARSLDGLVLLARAVGP-RRGSDATRLAVVTRGLAPVAGAPSAQALALGPVRTLPLEYPALTASV
IDFEAAEDGTEDDFAAALLAEVYAGLPDSLVAYRGSVRHVERVEQVP--TGSSWAQSRFRRGGVYLVTGGFGGVGTEIAGWLARNHQARLVLAGLTERWA
LEDEIRRRLALIRRL-ESAGAEVHVECFDVTDREAVAQALGRAEARFG-PVEGVIHAAGVAGGALAQFQRSETMRQVLAPKLDGTLALAAALREHRLAFF
AVFSSVSALLGNVGQVDYCAANAYLDSWACSPE--APEDAVTIAWDTWRGVGMAAPERLPAAV-----------------VAA--------HADQEWSGI
PAA----------------------AALAVFEQA----------VSGGQRRV--------LVSTDTLPDRLAARRRPEPAGPGTPVERSRAEVEETLIDI
WRNLFGRSEIDVDANFFELGGDSLLVVEAGRQIKERLQTTLPVSDLFKYPTVAHLVDRLSSDP---------
>tr|A0A069JM55|A0A069JM55_9ACTN Uncharacterized protein OS=Streptomyces sp. NTK 937 GN=DT87_01010 PE=4 SV=1
QAGDFADRITLRRRSLGDRTTVPAWCFVPEWNQVAAPAAGP-------------------------ARRVLWLRSGAPFEGFEEGGARFRTGHKEDLEAL
LEASARLGLDAV-VEARWHARPEDDGARTAAAALTEAPAAWGPLL--RAAAQLPAPPAVVLATRAAAAVTGDE-ESVAHAALTGVAESLAQSRPRLPVLL
VDGATD------D---DLLTECALRGT-GQVAHRDGTRLVRGLRPLDGASIPPVPRRVLRAGGSYAVVGGLGGVGAHLTQHLLRQFGARVLVLGRDAAEP
GTARGG-IRAHLADQAGLEGAAFRYTPLDATDVPALRAALDRAEADWG-PLDGLFNLAGSVAEQLELLPGGETAPQVPETRLRISHALDEALTGRT-TPL
VVFSSVNGFFGGAGFTEYAGACAYLAAHAAWSA-RRTGARLCLDWSMWKQVGMAAGSAVTELAGRRGFATIGPAQGLASLHTALDAAEDRVLIGLS----
PAGEAVAG---LLPFTASAFELEADGTHD-----PATIAALT-----GV------DVSRIRRTSTGAGDRAAV---------------GAAHTE-ALLDV
FRDVLGDGQVGEEDNFFAAGGDSIRAIQVVARAAE-RGFRFSPLDLFEHKTAAALLA---------------
>tr|D3P0F1|D3P0F1_AZOS1 Polyketide synthase OS=Azospirillum sp. (strain B510) GN=AZL_a05990 PE=4 SV=1
LAGDHAERITLRNARIGERQHVPSWTYVPEWVPAPLPRGGE-------------------------GGGILWLWSGGAFGGFPSGTASYDPADPEDIARV
VAAAARYGLERV-ICGRFAGTPADTAADAALATLAEARSRWKAIC--RAAEALEPAPVVLFATSGAFCADGSE-TRIGQAVLTGLSATLGQEHPRLRVSL
VDGATT------LA-AALAVED--GET-IRVAYREGVRLVPRLRPVETAAIPEQPSPLLRKGGRYLVIGGLGGSGAHLCRHLLTAFSANVLTVGRSEINH
AGGRAQ-AFAHLRAHAESTGGRIAYARADATDPAALARVVSTAETADG-AFDAVFDLAGSVSERLSGTSGTDGTDLAFAARIRVLHAIRTAC--PS-RPV
IVFGSVNGFFGGAGFADYSAACSYQAAFAASAA-ARGDGAVCVDWSMWKATGMAADADLRALARRRGFDTLAPRQALGSLHVALAEAAPHLLVGLY----
AGGTMVMP---HLPPRRIRTRIEATGTTD-----AAAVARAV-----GV------PEDAVRCRSRGAAAEAHV---------------PPEQAD-ALLAI
FRDVLVRPELGADDNFFGNGGDSIRAIQVVARAAA-IGISFKPLDLFEHKTVRTLLS---------------
>tr|L9PII9|L9PII9_9BURK Polyketide synthase OS=Janthinobacterium sp. HH01 GN=Jab_2c35360 PE=4 SV=1
VAGEFADQIVLQGQGLGERVVVPDWHFTLDWVAAAAPPA-A-------------------------ARRVLWLLPGAPFGGFGAGRASYRPCVAAELSAV
LAADELLDLDMV-VEAHALAPPQDDDAAVAGVALAAAHGHWEALF--AAAELLPQAPALVLATSAALAVDGSE-AGVAHAALPGVAASLAQSRPQLRVAL
VDGVGA------DA-AALLRERPGAGI-SQVAYRGGARLTPMLRPLPAAQTPLQPRHILRPGGRYLVIGGLGGVGVHLCLHLLRNFGARLLVVGRGRLEQ
NPPRAQ-ALAYLAEQAAVDGAGIDYRQADPADADALPRALRAAAQDWGAPPDAVFNLAGSVAERLAALEADGGAGAALRERIALLHAVERALAGGS-VPV
VTFSSVNGWFGGTGFVEYAGACAYQAAYAGWQA-RRGARHLCLDWSMWKQVGMAAEAALVALARRRGFDSLSPAQALASLHLALEHGAPRQLIGLY----
PSAPAVLQ---LLPPSLVRHRVEAAGAVA-----AAQVAAAL-----GV------APELV-RCSHAPRPAAAL---------------PAAHAA-ALLAV
FRDVLVRPELDLDDNFFASGGDSIRAIQAVSRAAD-RGLTFSPLDLFEHKTVAALLG---------------
>tr|A0A0P1BFA4|A0A0P1BFA4_9BASI Polyketide synthase OS=Ceraceosorus bombacis PE=4 SV=1
----------------------------------------------------------------------------------------------------
-----------QALICAWPLGVIDVSPES-----AMDHVDLISARLLSLMKALVNQTSAWSAVVITRDALHGHVSGVISSTLHGMVSGFAGRTTCVALDT
SALLRP------AQIASATEEILALSAFRYEIVDGVVRR---LAPSL-DKYPAQIQHRLPSEGTWVITGASGTIMTAILPWLVTSQRQQVAIFGRRKRDP
DY---LADVRKR----LPAGVQVHYETVDLHSSSSVSNAMNRLPG----TVKGIVHAAGVTRPALVRGQSREAYDEVFAPKVKGAWNLHQHAPS-TLEHF
VLFSTFATVNVFPAMTNYIAANFFLNSLASFRR-TQGLPAMAIGFGSWPGSPMLDGLSPALNA---ECPPLVDTKAYREIEKLMLMQRPPAKYRLDPQHL
LDSLASQRSASSPRLPA-AASTSDDITG-ALAELPAS----LMQSDSA--AVQATPSPPAPPASNGFSTSVFPSRLLEASELEAAPGAEARHVTRDIREL
VLHIFAREEFRDDQRLETYGWDSLYHLELTSQVKEKLGIELPESLDTGMATLQEICAAAAEA----------
>tr|A0A0F0HJ91|A0A0F0HJ91_9PSEU Uncharacterized protein (Fragment) OS=Saccharothrix sp. ST-888 GN=UK12_32200 PE=4 SV=1
-----------------------------------------------------------TGRLRESGEQVVTVTAGTDYERTAQDAFRVRPEIAGDFEQL
VDALEEQGGRTWNVLYLWNVEAGA-SLE-----QARVRSLDGLVLLARAVGP-RRGADATRLAVVTRGLAEEEPAPAEQALVLGPVRTLPLEYPALTASV
IDFEAAADGAEDGFEQSVVTEVRAALPDSLVAYRSAVRHIEHVEQLPTAS--AAAQTRFRQGAVYLVTGGFGGIGTEIAGWLARNYQARLVLTGRTPLPP
TEAEIRRRLALVRR-LESAGAEVHVECFDVTDREALAQALGRAEARFG-PIEGVVHAAGLAGGGLAQFQQSEAMRQVLAPKLDGTLALASALREHRLAFF
AVFSSVSALLGSVGQVDYCAANAFLDTWACSPEAPE--GAVTIAWDTWRGVGMAAPERLPAAV-----------------VA--------AHADHERSGI
PAALAVFEQAVSGGQRRVVVSTGT-----------------LPDRLAARGTRHLEPT-----------------------RHDTPVERSRAEVEQTLIEI
WRNLFGRSEIDVDANFFELGGDSLLVIEAGRQIKERLQTALPVSDLFKYPTVAHLVDRLSPD----------
>tr|A0A097I358|A0A097I358_9DELT GulA OS=Pyxidicoccus fallax GN=gulA PE=4 SV=1
----------------------TDMLYRLTWEEAPSPEVGASLARRWLVFADDQGVAEAAAGLLSSAHAVHRLHPADAFRRDG-NDFHIRPNEPEDYRAV
LQALLSRGALPLGVLHLWNLRLPEGATAVPDLREMAKLGNLSLTHLLKALDG--AGSAPPRVWIGTWALPGSE-QGLAQSAVWGLTRAIAQEHPALWGGI
IDLDPLEAP--RLQAERLVTEVSVPQPADRILYRQGRRQVSRLVRDTAPVSA--ATATFRGDRGYLITGGLGELGTRLAAWMVARGARHLILAGRKALPA
RRTWKQDGIDAVL-HLERLGAHVHTPALDVGDGAALAAFLAGYEQEARPPIAGVAHLAGVIRPELLARLREESLEESFQSKVYGAWNLHQAFSGRGLDFF
TLFSSASAVLNSPLLGSYAAANAFLDGLAHFRR-ARGEPAQSLNWGFWSEAGMAA-----RDLHFD--ASASGQQGMRSFSPAVGLD---IFGGL-LSRD
PVQSVVM-----------DVDWK------LWLEAYPAAASPLLRTLRASEGVA-------AGSEQAAPAEEASRSL-----RDLPAEERRKAVEGILLTE
LSAVLKMAKISRTALFGSMGLDSMLSLELRNRLERRTGLTLPGT----------------------------
>tr|X0MS98|X0MS98_STRA9 Beta-ketoacyl synthase OS=Streptomyces albulus PD-1 GN=P354_27885 PE=4 SV=1
------------------------LFYRPVWHDAPAPRAGRADRAPLLVLTDRAGTAAELAAAGGWRQ-AVEVLPGAGFERRAADRYVLDPAEPEHYRRL
LRELAADSRAGLDVAHLWSTEAPDGGPQHRRREEVFGRGLGSVLHLVRAVTD--AGVRVRCLYLHSGRGAAGVP-E--HEAVAGLALSTARHAPGIELFT
VR--HDPARDGALPAAVLAAELTADGALREVRYEAGRRSVRTVERAPRPATPADGAAPLVEGGAYLITGGAGGVGRLLARYLAARYRARLVLLGRSPLPE
------AVRAEL----EELGAQVLGVRADVADAGQLRAALIEARGRF-GGLDGVFHLAGVADRVPLTEVDDAGFRRALAAKVQGVVNLDVLTRADRLGVF
AAFSSVSALCGDFGAGSYAAANRFLDAYLAVRRVASGERTLSLDWPLWDAGGVDALVELDTYQEATGLLRMTPRQALDAFDRAWQFDAPVLVPVLDPERI
ARTLGGAAVPPAATRA------G----ASTEP----APAARLTPPAAHPAPPA-----------AAPTDA----------------ERYLPAVVDRLRRT
LSGVLKLSAAQIDSQLDQYGIDSVMIMEVNSLLGRDFT-GLRGTLLFEYRTVQDLAGYLV------------
>tr|H0K8N7|H0K8N7_9PSEU Beta-ketoacyl synthase (Fragment) OS=Saccharomonospora azurea SZMC 14600 GN=SZMC14600_17385 PE=4 SV=1
------------------------VCYVPDWRSAAPGPQGSR-GDVLVIFSREPSSAARLGRLGGWPR-TIVVCDRTAAAEAPGDIHVIDPVDANAYRDL
IAGLP--ATANVDVVHMWTTPHPEVGDL----DEEIGRGAVSLLLLAQAVRA--SGRRTRCVSLHRDEDAADVP-A--HELIGGLASTAARHLPHLELCT
VH--VPSTAGVEWLADVLRGELSAVTSPRDVRYDGARRTVRTVRRLTGD---PAAAAPPTDGGVYVLAGGRGGVGMQLARHLARTYHARLVLLGRSAPPE
------HACAEL----ESLGAEVLAVRADLTDAHQTRAALVEARGRF-GHLDGVFHLAGVADQQPLTDVSGERFRSALAAKVHGVVNLDRCTRADRLSFF
VAFSSVSSLIGDFGSGSYAAANRFVDAYVRRRWAADGLRSVSVQWPLWEAGGMDSLVELTAYRETTGLDRLSPEQAMRALDVVWRYDVPVLAPVHDQELI
ARVLTGEESAV-------------------------SEPERLTQHPSAPVAPS---------------PV----------------GTRTAELVDYLRNQ
ASGVLKLDPAQIAGPLQEYGIDSVMITELTDAVSDAFP-GLRGTVLFEYRTLADLAGYLL------------
>tr|B2WW47|B2WW47_9ACTN PKS OS=Streptomyces albus GN=ozmN PE=1 SV=1
------------------------FFYEQVWRDEDVVAGAAPGSDAVLVLGDGDEVARGLAGRTGVRR-VVDVRAAAGFARTGPDRYAVDPECPGDFERL
LAELARDGVRSLDVVHLWGLTAEPVGYGEAALDGAFARGLHSLRSLALALHA--VRHRVRCAYVLADPERGPRP-D--QEAVAGFALSLTGVLPRFELFT
VA--CA---DGLDLPGLLAAELTQGGRPAEIRHAATGRQVRVLRRAEET--RTAAAVPLKRGGTYLITGGTGGIGLELARHLAATYAARLVLISRSAGRP
PA---REAADGL----AALGAEVLLVAADTADPSGMRAAVARAKERF-GHLDGVFHLAGAADQCSLLDAEAARFTGLLSVKAHGVRLLDALTADEPLDLF
VVFSSIASVVGDFGACAYAAANRFLDSYAEERRVREGRRTLSAAWPLWRIGGVDALMERTGYRHRTGMREFTGEEGLRALDLAWRTGLVRLVPAVDPDTV
DAALLPRPAAGARADS------G----AATAATRETAVPASAVPHAAGPVAVTAVT-----RTNGAAVPA----------------SALLDRMRDHVRAL
LGQVLGLSVERIDDALDAYGLDSVLVMETNEHLDRDFP-GARGTLLFEYRTVHDLAAHLL------------
>tr|A0A0C5VQN4|A0A0C5VQN4_9GAMM Polyketide synthase modules-related protein OS=Gynuella sunshinyii YC6258 GN=YC6258_03672 PE=4 SV=1
-------------------------------------------------------------------------SPTVAMPATDHSIIVLCGSAPELETAL
TAHLPQGQTVMSLNVPVELTDT-DDRY---------REMVNGLLQILQQTLKSNGSDTIFLLVVFS-TDEVDHAHLLTGLSGLLKTAEQEYSRLTTQML-
----EIAAVDDAAQLYAMLSANLHQPGSDRIRYQNRQRQVHTWKPLSEEIEL--SAKPWRHKGVYLITGGAGGLGRMFACEILTQSPGRVILTGRSA---
---IDPAQVNALRKY----GGQVEYVQLDVTDRAAVQALMLH--LRQSYGLHGILHCAGVLQDGRLLAKTTAEVEQVLAPKVTGLLNLDEASRTMELDFL
VLFSSLASALGSVGQADYAAANGFMDAFVDHRNALRNLGQLAFDWPLWREGGMSVEAETEQLLQQRGMTAMRTETGMNAFYLGLASKSTRIL--------
--------VVEGELARIQQTVLRREGVLGIQRLPKPRIEKQPQATSAPE-----------------TGQSDGTHGVIR----------RLKVIVSQLVHI
-----DPIDLDVDEELNAFGFDSISLTRLAGELNKEYGLSLSPVVFFEFPTLAQLAEHLLAE----------
>tr|E1ZE56|E1ZE56_CHLVA Putative uncharacterized protein OS=Chlorella variabilis GN=CHLNCDRAFT_57723 PE=4 SV=1
-------------------------------------------------------------------------LPTGSGANGGRALALLAGTAVNQDGRS
SSLTAPNGPSQQEVVYQALGAA---RL---------EPFAVTALQMHGTGTSLGDPIEVGALAAA--LVERRPASWAAPLSLLAAKSWSGHAEPGAGMV-
----GLVHAQQHVNPYVAGAMEMAAGKQAGWAVPRQPGALPTATTAGGNRGQ--LAAIKAARGRIAVTGGMGSLGLVLARWVEDAELAQLVLFGRTGR--
--LAGTEAAALLANS----AAAMTLAMADVAGSEGSSSALEP--AAGSMALTALFHSGGLLADATLAKQAPAGIRAVFSAKVTAAQRWQHTVQAQPAAAQ
VLFSSVAALLGSGGQTNYSAANAALDAMASNHQQKGLLTA-SVQWGAWSGGGMAAQDRSTVLRVQRGMAMIDAARGMGALFTAVPFNWPTFIGRL-----
-----GGKPVPSMFAAFADQ-VAPALTAGRRPAARPVVAAPRVARQSAV-----------------PPHTSAALEVFKQ--------HVAAEVAAAARSI
-----LGADVGANEPLVAAGLDSLSSVELRNSLEGKLGLELPSTLVFDYPTVNAISQFISTN----------
>tr|Q6MZA4|Q6MZA4_MYCUA Type I modular polyketide synthase OS=Mycobacterium ulcerans (strain Agy99) GN=mlsA1 PE=4 SV=1
-------------------------------------------------------------------------EPTQQLPRYLHDLHTSTDLHTSTTEAD
VVVWPVPVPSNEELQAHQASDTASSRI---------HTLTRQTLTVVQDWLTHPDTTGTRLVIVTRHTSAHDPVPDLAHAAVWGLIRSAQNEHPGRFTL-
----LDTDDNTNSDTLTTAL--TLPTRENQLAIRRDTIHIPRLTRHSSDGAL--TAPVVDPEGTVLITGGTGTLGALFAEHLVSAHGVHLLLTSRRG---
---PQAHGATRLTDL----GAHVTITACDISDPEALAALVNS--VPTQHRLTAVVHTAAVLADTPVTELTGDQLDQVLAPKIDAAWQLHQLTYEHNLSAF
IMFSSMAGMIGSPGQGNYAAANTALDALADYRHRLGLPAT-SLAWGYWQTHTGLTAHLTDVDLARMGLMPIATSHGLALFDAALATGQPVSI--------
--------PAPINTHTLARH-ARDNTLAPIPRRRAASAATDLAARLNGL-----------------SPQQQQQTLATL----------VAAATATVLGHH
-----TPESISPATAFKDLGIDSLTALELRNTLTHNTGLNLSSTLIFDHPTPHAVAEHLLEQ----------
>tr|A0A0H4TMU3|A0A0H4TMU3_9CYAN ColF OS=Moorea bouillonii PNG5-198 GN=colF PE=4 SV=1
----------KLHQRQVAQASVSELLFQIEWQVQPPLSQDSLQPGQWWLLAENKGLASELAEYFTQQGQCHWLESDPS--QLS----------KERLETV
LSQLTNQTLPLHGIIYLWNLNKPSDELPDGDWQQSIK-PLLQLVQVISQLPGFQS-----KLWVVTRQAQAVDPVAISQTPLWGLGRVIAQEQPQLWGGL
IDLEENQ---ELTAAQQVYTEVATQPGGLQVAYRQGKRYWPQL--VRYPKIP--PSLKLNSQSSYVLSGGLGALGLQIAQRWVEQGARNLVLLGRRGITN
--EIQQQKIAELEA----AGAKIQVASIDVSNWTQLRQAWTEWQST-MPPVRGVLHAAGVLDDGLLENQSWERLVKVMSPKVEGGWNLHRLTQDENLDFF
ICFSSAASVLGSAAQSSYAAANAFLDGLCAYRR-SLGWPGLSFNWGPWSEVGMAAQMAQKQRWAMMGVKLIQPEQGLQVLEQQLGAGGQLGVLAFDWEVL
SQKLSPTQ----------LNFFA--------QVLPPEVKDLVQSTT--ER---SSQLQQQLL--------------------LVSEAQ----RKQLLRQT
LQEVACVLGLPPTDGFFELGMDSLMAVELRNRLGQLLAVNLPSTLTFDFPNIERLSDYIISE----------
>tr|A0A0G3A003|A0A0G3A003_9DELT Malonyl CoA-acyl carrier protein transacylase OS=Archangium gephyra GN=AA314_06711 PE=4 SV=1
----------DQDSATEAPDGTRGDLYALEWQSAPRASAPAPASGTWLLLCDRGGVGEQLASSIEAQGACVKVDAGDA--TAL----------ERVWR--
---ERSASSPCAGVVYLGALDVTSVEGPI---RESCV-SVASMLRVVEGSPEPGG-----RLWVVTRSTQSVGKVEPAQATLWGLGRSVALESPGRWGGL
IDLGPED---G---ARQLWEELRSARDEDQMVLRGGQRYVARL--VERESES--KPVPVQAEATYLIAGGQGALGLEVARWLVRRGARHLVLTARRAMPE
--RSQITGVRELEE----AGAKVLLAQADVALREDMAALLERMRAS-MPPLRGIVHAAVVSSTSRVRDLDADTLERVLAPKVAGAWNLHTLTRDEPLDFF
ILFSSISAVWGSSGVGHYSAANSFLDGLAAHRH-ALGLAATSINWGLWSGRGAASE--EQGRWLMMGVEVLDRQAALGWMERLVGSRVPAMVATIRWERF
LPIFEARG----------PRPLL--------SRLRTEL-ELPVV-----K---SSAPAPWRE--------------------APTATA----RREALRKL
VQSVSRILGLQPGQGFNEMGLDSIMAVEVKERLQKALSVPLPATLAFNFPTVKALTEHLSSL----------
>tr|S9Q289|S9Q289_9DELT Malonyl CoA-acyl carrier protein transacylase OS=Cystobacter fuscus DSM 2262 GN=D187_009025 PE=4 SV=1
-------------PRPAPEGGSQGARYEVEWRPSARVSEVSPARGSWLVLG-EGEEGRRLAAHLQSQGACVTVAP-----SAF----------AGVWR--
---EH--AASCTGVVFLRALET-----EA---HEACL-ELASVLHVLEGTPDAAA-----RVWVVTRNAQSASRVNPSQALLWGLGRTASLESPQHWGGL
IDLGPEE---G---VERLWEELGAADGEDQVLLRDGQRYVARL--LEREAEL--QPLPVSADATYLITGGKGALGLNVARRLVRRGARHLVLTMRGAFPE
--RSRIAMVRELEA----AGAEVWLAQADVSQRDAMAALLERMKGA-LPPLRGIVHAAGVSATARVADLDAETLGRVLAPKVDGAWNLHALTRELPLDFF
VLFSSVAGVWGSSNGGAYAAANAFLDGLAAHRR-ALGLVATSIDWGLWEGAGLATI--EERVWLEVGLDALDREAALDWMERLVAARVPAVVASIRWERF
RSLLEARR----------ARPFL--------ADLRVHGRALPEG-----K---APPRPAWKD--------------------AATPSA----RREAVGAL
VRTVSRTLGLSAGQGFHELGLDSIMAVELKGRLQEQLGLTLPATLAFNYPSVRALTEHLDSL----------
>tr|A0A0M4KE03|A0A0M4KE03_SORCE TAT polyketide synthase OS=Sorangium cellulosum GN=ctoE PE=4 SV=1
---------------------------QTEWARSAPARGDRLPPGDVLLFDAGDGIFERLRARWTGGGRVALVKPGDGYREIAPDIHAIHPARPEDHARL
LEELARRGAAPRIVLHVAPRGALAPSEAVADVH--LERGVLALFLSVRSLLERRERGALHVLHVSAVEGGEPQP---QHAGVAGFARSLRKEDPRVRCRA
VALDGAPD--PAAYVDAMLLELSTDDGAAEVRHAGGERFTRRVAPLDLPDRARV-----REGGGYLITGGAGGLGARLAAALASASRVRLVLAGRSGMDA
R---KQELVRSLS----AGGSDVHYASADLSRREDVERLVRE-ARRRCGAIHGVVHAAGVLADALLVNKTPEAVRSVLLPKVRGSVWLDELTKGDELDFF
VLFSSIAAVVGSAGQCDYGYANAFLDELARWREGARSGRTVSIDWPLWREGGMTVDAAHRASLEEAGLALLDTGAGIEAFHAALRLPSPQ----------
----------------V-VVLYG-DPA-----R-----AAALLTAG-GGAPA-ESPSSPL---EGG-AD-------------------LREAAEAYLRSL
LSSHAKVPRLRPSEPFESFGIDSLMSMTLVRALE-KTFGELPKTLFFECRTLSELAVYIDNH----------
>tr|G2G4P9|G2G4P9_9ACTN Pks12 OS=Streptomyces zinciresistens K42 GN=SZN_02262 PE=4 SV=1
-----------------------------------------------------------LGRLKAGESVLVHAGVGMAAVQLRHLGAEVYATASP---GK
WETLRAMGFDEKHIAS-----SR-DLDFEPRFMAATGRGMDLV---LDSLAR-----EFVDASLRLLPRGGRFLIDVRDPEV---V---ARDHPGVRYAA
YDLDAADYDMLVELVELFDSGALHPL--PVTAWPDAVRYISQARHIG--KNVFTMPRALDPDGSVLVTGGTGGLGREVARHLVERGVRNLVLVSRRGPDA
EGA------ADLKAELTRAGASVTLAACDVADRAALERVLSGIPT--DHPLTAVVHAAGVLDDGVIDTLSPKRIDAVFEPKVDAAWHLHELTRDTDLAEF
VMFSSAAGVFGSPGQGNYAAANSFLDALAAHRR-GLGLPAVSLAWGPWEQAGMTGTLADMVRMAREGMAPLSMAGGLRLLDAGAASEDAL-LVPLETSAL
GGQT----------------------------G----VPTLLRGVVR-VRSRAA---------ADGKAAPE---SAKVRL-----AGLAGAELDRALLDL
VRGHSGAQSIEPDRSFQSLGFDSLAGVEFRNRLNSATGLRLPSTLIFDNPTPAALAEYLRGR----------
>tr|G2PEV9|G2PEV9_STRVO Beta-ketoacyl synthase OS=Streptomyces violaceusniger Tu 4113 GN=Strvi_4164 PE=4 SV=1
-----------------------------------------------------------LGKLQEGETILVHAGVGMAAVQLRHLGAEVYATASP---GK
WDTLRAMGFDEKHIAS-----TR-DLEFERRFTEATDRGMDMV---LDSLAR-----EFVDASLRLLPRGGRFLIDVRDPEV---V---AQDHPGVKYSA
YDLDVADYDMLVDLVDLFDRGALHPL--PVTAWPDAVRYISQARHIG--KNVFTMPSALNPEGSVLITGGTGGLGSEVARHLVERGVRNLVLVSRRGPDA
EGA------ADLKAELTEAGASVTLAACDVADRASLDRMLSDVPA--DHPLTAVVHAAGVLDDGVIDTLSPKRIDAVFEPKVDAAWNLHELTRHLDLAEF
VMFSSVAGVFGSPGQGNYAAANSFLDALAAHRR-ALGLPAVSLAWGPWEQAGMTGTLADMVRMAREGMAALSMADGLRLLDAGRTSEDAL-LVPLETSAL
SGQT----------------------------D----IPTLLRGAVR-VRSRAA---------ADGKATAE---SAKEQL-----AALSGAELDHALLAL
VCGHSGAQSIKPDRSFQSLGFDSLAGVEFRNRLNSATGLRLPSTLIFDNPTPAALAEYLRGR----------
>tr|K3VA96|K3VA96_FUSPC PKS6 OS=Fusarium pseudograminearum (strain CS3096) GN=PKS6 PE=4 SV=1
-----------------------------------------------------------VAKLKAGESILIHAAVGQAAVILQHLGAVVYATCGS---QE
KER-ESMGVNPSHIFT-----SR-SPAFGPALRAATNKGVNVI---LNSLAG-----ELFRESLECLTSFGRFIKDFLDDAL---M---PTKFLLITFAC
VQMINEDKPLLNDVVELVASGQLKDEV-NLQLYESAFRLISAGKHMGK-VINI---PKLLPDATYLLVGGFGGLGVRLIRWLASRGAKTIVTMSRSG---
PAA------KTCIEEMDSLGVRIIAKSCDISSKEALQVVVKELEDVDGAPVRGVINAAMALEDAMFDQMTHQQWVSSLAPKVAGTRNLDEV--LNYMDFF
VVLSSIAGIIGHQAQANYAAACTFQDAFMHYRR-SQGRASFAIDVGVVSDAGVSEAPAVFSNMKRQGFSFISVAELLATLDYAL-SNGPDCSIGAEASPN
NAELEQ-------------------------RR----ISHLVKDSAN-G----A---------AGGS--DA---DHIGH--------IRSAKTAEEALDA
VGQVTPVDRILPHRTLDSYGVDSLVAVELRNWVVAIVAADLSLLLIRESRSIEELIHLVAGK----------
>tr|A0A0B4HLK4|A0A0B4HLK4_9HYPO Beta-ketoacyl synthase (Fragment) OS=Metarhizium majus ARSEF 297 GN=MAJ_07758 PE=4 SV=1
-----------------------------------------------------------TARLSAGQSVLIHAAIGQAAIMLKCLGVTIYATAGS---QE
KGLQREYGIPAERIFT-----SR-DASFATAVLAATKRGVDVV---LNSLPG-----PLLQASLDAIAPLGYLIKDIESNSL---V---ALESFSISLVS
LTLLR-RGPALGEMVRLIEQQALKPVH-PIAVYQAAFRLVQTGAQMGK-VVGVTARVRLQADASYLIVGGVGGIGRSVAHWLVSHGARNLMLLSRTANKN
THG------ARFVRELREAGCRVKPVSCDIALASSLTTALRAC-EDDGPPVRGVIQGAMLLRDAVLEQMTLDDWRGGLRPKMHGTWNLHTEFSQASLDFF
VMLSSVSGVVGIASQANYAAGGSYEDAMARWRQ-SRGLPGVAIDLGPISDIGVSATARVAERLRKDGFAMLDEDTVLRALHAAVLHPGGRAIVGS---AP
GPQDAT-------------------------GR----S-QLGRDARF----------------AAA---GT---SLAAQ--------LAEATDQQEGARL
VGAMTPVAEIDLAKPPAHFGVDSLIAVELRNMLVLQAAADISIFNILQTASLAALAALVAEK----------
>tr|A0A085WVX2|A0A085WVX2_9DELT Malonyl CoA-acyl carrier protein transacylase OS=Hyalangium minutum GN=DB31_0096 PE=4 SV=1
------------------------LLLVKRWRPAPAPVTAPTLRGMYLVLLNGEGAIDVLKDLGSQPEQWIAIKGASGLPRLTAREYELDFSDGEQGTRL
ITELLSRHPQVNGLVDLSDVYAAPR--VSPD-RDAGKV--AVLQGLLRHTGQ--APLRILHFT-HGLVPFENTVPTLAGATVAGIVRMLGAEYGRVRAVT
VDVDLSC-DRSEELLALVAAEASADTGMGEVCYRKGTRYLPYLEEVAVSAPGEALGFPVDPARTYVITGGTGGLGFEAARTLVAKGARRLALLGARTLPP
RDSTEQDVATRVRRVLEQAGAQVALYHGPLSDEPRLAAFFSDTRKRL-GAIAGVIHCAGIVSQRPFSQKGLEDMRRVWEPKVRGLIVLSGVLKADTPDFF
LLYSSVSAVVPSLAVGDYASANGFLDAFAAYQAGKSRTRFLALNWPSWKDTGMGEISS-------------PRYTG--LGFTAHGTREG-----MELLEA
ALSLPD--------------------------------TTSVMPCVVNRATLRLDRMLSTQGAEPAAPARAP--QAAP-AAQADTPTPLFAATRELILEL
LSREIDKARFQGDAPFGDYGVDSIVIADLVTKMERFTGKPVDPSIILEHSTLDTLSHYLSE-----------
>tr|A0A0C5VNB2|A0A0C5VNB2_9GAMM Polyketide synthase modules-related protein OS=Gynuella sunshinyii YC6258 GN=YC6258_03740 PE=4 SV=1
------------------------RFFAPVWQPQTLTAS---SRKTVLLLVPETEVLAWSTRMDDRVADWYVIRFAGLMPRLSKRELEIDVWAEQAFDDL
LAMCAERHLQPDWIVDVCDFGPD-------SDQWQARI--RFLQLCVRAWS----GLALFQIS--------DRQSSRTRQWFTALYAGLAAEYRQISCRS
VVFD-QA-PPFTELEPLLERELQ-GGDSRPVSICDGQRQILSYQLCNLPQAGQI--RGLDSEAAYLVTGGLGGLGLQAATLLRQLGAKHLILLGRRQPDE
TRS-----------LLSNGSAQIEYFHDLSTLA-------ERLQQQP-VRIAGVIHCAGIDTQGEFVNKPVSAFTDCLAPKVVLAEQLTPHLDPAALTFF
IAFSSVSTVVPALTAGDYGPANAALDQWVATMAGQPQSGFVSVQWPSHQQGGMPVVVS-------------DVYRD--TGLANLTREQS-----DDILKI
LITLAL--------------------------------QSTLLPHVGDGSPV----LFSKDVFEPA----------IK-VPGE-IPRPARTLILTRLTAL
FARQVDESALQAGVPFDELGIDSILIADLVRAIESEFDCILPPSAILEYPSLGQLTEYLGE-----------
>tr|C5BJI1|C5BJI1_TERTT Modular polyketide synthase, type I PKS OS=Teredinibacter turnerae (strain ATCC 39867 / T7901) GN=TERTU_2202 PE=4 SV=1
------------------------VFYRPAWEPCPLESNAASYTRTILLLVRDDESVLWHERIAQSPRNWHIVRFSGLYPRLSKTELEIDLNAENPITQF
IQLLEHRHIRPDWVIDAFDFAATQE--ATASSFWLQRV--QLLQSCMRAWQN--AGVHFWHLS--------GSNGSAQSAWFETLYAGLGVEYKNIQTHQ
LQLE-SC-PVIREFEAVLEQEAMQPATQQSVSRRSGSRNVRQFEPITLSTNSSS--VFLRADAVYVVTGGTGGLGVVAAKLLISCGARQLILLGRKPLGE
KGE-----------VLSEKGATVNYSSSVNDLK-------TRLQSER-LFVAGVIHCAGVDTQGDFINKSSSSFEKCLLPKTELAQRLKPHLDPAKLQFF
IAYSSVSSVVPVLTAGDYGPANGALNSWVAAQAEHSNSGFVSILWPSHESGGMPVITS-------------ERYQN--TGLACLTEDQA-----DQFLRV
IMQAAI--------------------------------QVLILPHLDISLPL----NLFPQKSSSAMLAGVS--EASN-LRGENIVSPGSSDLLASLTTL
FAEKIAQENLAAEAGFSDLGIDSILIADLVRAIETKFECVMPPSAILEHPTLAQLADFLNE-----------
>tr|A0A078KNJ1|A0A078KNJ1_9FIRM Uncharacterized protein OS=[Clostridium] cellulosi GN=CCDG5_0919 PE=4 SV=1
-----------------------------------------------LVITDGTGIFDEFISVLKAKATLIKAQLGSQFSRVD-ENYIID-GTQKDYERL
VKDVEEYGISTV--VYLLSFTGNKTINSAEELEEVQNSHSEGLLYLVKALGNTENKIELVIVSDNVNEVTGRESINPENAITFGMGKCIGMEYENIRCRM
IDFDE------HTDAAVLVKELCNEADDWVVAYRDGERYVDVIEKVDKSALND-SGIPQVSEGVCLITGGTGRLGLKAAKLIASKGKANIALVSRTPVPD
RTAEADKVINTVREI-EKSGSKVRCWSCDITSAYSLSNLLAELRREY-GRIGGVIHCAAVGGGALINQETWESVNAVLLPKVRGTWLLDKLTRQDKPDYF
VMYSSGITLIGGYCSCSYTAANSYLDSFAAARN-RSGLRTLAIDWPVWENDQLDKNLMFK-------ILPIEK--GLQCL-DELMH--------KDIARV
IVGEMNFE-------SEILTMEG-----RIPLRLSDELKTKLRTKTTETKPVLS--------------------------SKTPSYDAAGSDTEKMIAQI
FADVLGYERVGKYDNFFELGGNSLLAIKA-EAIASKRNLNFSYSDIYKYQTVEQLAAFIDDS----------
>tr|F1T733|F1T733_9FIRM 6-deoxyerythronolide-B synthase OS=[Clostridium] papyrosolvens DSM 2782 GN=Cpap_3713 PE=4 SV=1
---------------------------------------TKEDRT-LLFIAEDMKFCNNYGYFS-ENTISVYIGNEAS-SNM-KYNYQINKTDSASYINL
YEQLNKKKCSEWDIIYFS--QSRNT--GADTSAKEIDNSIQTAYSLIRAFSKDYSTIR--FIHGFTKDNH---T-NYVNIALSGMLKTISVECSNIQFEN
MNE--------REICSRLIEEVNFISDGTDISYISNKRYISEFKPIQKSET-ENKQLDIFNQGVFIVTGGMGALGQILAEQILVYRPQRVYLLGRKYPDK
---AILDSVSRID----PSSTVIKYLQCDIEDSIACQQVIENILEKDG-HVTGLFHCAGVIRDAIIVNLKLEDFYQSVNPKIKGLINILDSKYGLDMKFV
KLYSSITSVMGNMGQTAYSYANGYLNAFAYDQSKYHMFNIQAICWPYWEQGGLTVGEKLNRLYEQTGQKPLSTANGKIVLENLMSLDSKCP-IAMYGDKA
KISRYMKEVR----------------------RQYT----MEENEIQGDEIV---SASKLKEDVT-----D------------------------YVQGI
ISDIIKKSKLNITTTWENYGIDSLAIMRFNEIIED-VIPNCPKTLMYEYRNIEALSEC--------------
>tr|A0A0K6KX51|A0A0K6KX51_BACAM Polyketide synthase PksL OS=Bacillus amyloliquefaciens GN=pksL_4 PE=4 SV=1
---------------------------------------NQQAPGNMLIFDQDNRLFQHAEMMNGEHNRVILVTPDSD-YRIERNRCTINPSDENHVEML
LADLAENGFTPDIVLYLWNGEIREF--TEESVNETLRRGINSLFLLSKALMRRNEPVT--LLHIYWTSGL---N-QPFHEAVGGFIKTVNMESSTIQIRH
EHSEINPPV--SEVWDAAISEIQHQSDECEVLIDSHTRYVKGLQHIDNPEH-DNGSVTYQKGGIYIITGGAGKLGLLFAEHIAKENQAVIILTGRSFLTA
---DQKERISKLN----ESGSIVEYQRTDITDRTETERFIFGVKQRYG-SINGVIHAAGILRDSFLVNKSLSDFTDVLKPKVYGTIWLDELTKDEDLDFF
VLFSSF-SAYGNAGQSDYAYANHFMDSFAMLSQLSRNGKTLSINWPLLKDGGMSLSNGIIQIKEKYGMTPMRTSSVLEAFLKMLRSSFTSL-MPAEGERD
KMIKALSIQR----------------------NTAA----ADQDTLTAEHDE---EEEYAKEKVN-----D------------------------YLIKI
ISGVLKAHKINAKDSFEKFGINSLMIMSLISKLED-TFGDLPKTIFFEYQNIEELSNF--------------
>tr|X0MVA5|X0MVA5_STRA9 Uncharacterized protein OS=Streptomyces albulus PD-1 GN=P354_17195 PE=4 SV=1
---------------------------------------------------------------AGRADRIVLARPGTAYQRQDAHTFTLDPGRGADVDRL
FADCAADDLLPGVVLHAWNDPDGADGLAAGAVDAALARGLLTHFHLGKALLARKRPVRVL--HLHTAGVDGPSP---LQDAVAGFARSVRLENPRLVHQV
VGLDRR----EHALATA-VAELGDATDPAVWVHEDGRRLVHGHRRIDLPRPADR-PTPVREDGVYLITGGAGGLGLLVAEHLAAQARTHLVLVGRSEPDQ
DA---RRRMAAIE----AHGGTVRHLRADVADAESVRELVARVRAEHG-ALHGVVHAAGTLRDSFLLKKTAEEFAAVLAPKIAGAVHLDHYTRDEQLDFF
VLFSSIAAAFGNLGQTDYAAANAFLDAFAEHRTVARHGRSLSIAWPHWRDGGMALAAHDAAVLRERGVASLGNEEGLAAFDDALA--------------L
PGG-------------AVLVAAG--DAEVIAGRLA-AAGTAADDRPGGDAGA---GAEAAPTASGGADDGAE-------LRGAVAF-----LRELVARKI
GAE---ASGIDPKALLARYGIDSLVITELNRALEDRFG-ELSKTLFFEHDSLEEIADHLAE-----------
>tr|L8Q0A3|L8Q0A3_BACIU MlnC OS=Bacillus subtilis subsp. inaquosorum KCTC 13429 GN=BSI_21420 PE=4 SV=1
-----------------------TVFFKRDWISSKNDDVQKQAPRSILIFDRDKRLTEYISMLYKDQVHVILVTPNVYFSCLEQNVYTIDPSNEAHYENL
FADLEKSKFTPGCVLYLWNSAVPE--LSEELIHKALLNGILPLFVLTKALIKYDNTK------LLHMYWTNGQNQPFN-EAVGGFIKTVNMESSKLKAKT
LQIHREEPDS--DPTASQLWEMEILIDSHS-RYIKGMQHIDLEKSLAPK------HVSYHKGGVYIITGGAGKLGLMFAEHIANEVEAVIILTGRSA---
LSEVQKEQLRKLNA----KGSFVEYIQTDISERIKAEQFIRDVKQQHGQ-ISGIIHAAGLIQDSFIAKKNLSEFVEVLKPKVFGTIWMDELTKDENDFFI
LFSSVAA--NGNAGQSDYAYANSFMDSYAMFRQLNRNGKTLSINWPLWKEGGMNLDDSAVVHLKEFGMIPIHSTAAFKAFDK-MMQSSFSNIMPVDRDKL
LKTIPFRK---------------------------------------------LTPSDNEKNTEDEIVIKDKVN-------------------DYFIKTI
CSELKPNHKINAYDSFEKFGINSLIIMSLISKLEDTFG-DLPKTIFFEYRNVDELADFF-------------
>tr|A0A0F7EJ98|A0A0F7EJ98_BRELA Uncharacterized protein OS=Brevibacillus laterosporus GN=EX87_20440 PE=4 SV=1
--------------------------------------------------------------------RLVTIKVGECFQQKSETEYELNPANKQDFQRL
FEKLKKLEFKPGGILHTWGITIES---DV-LEATTVQRTLYSLVYIAQSLG----EQNMTNLTNNMNEVVGGDLLYPEKSTVLGTVKVIPLEYQHITCTS
IDISLPERGSKEHLVKEILFN----DTENIVSYRGSHRWLPSVKQIRLQKRHT--SSRLREKGVYLITGGLGGMGLHMAEYLAKTVQAKLILVSRSDFPK
ATWKDYEKIEKLRE-MEEYGAEITVISADISDKEQMSKVIKQTE-SMYGSINGVLHTAGVAEYDGVQTKQKKNIEKVFASKIYGTLVLHHLLQGKADFFG
ICSSLAPVIYTKLGQVAYCSANEFIDSYVHYYNSFNDGVVFAINWADWQEVGMSVES-------AKHWGQKLKLE----NSDSILEDGILPHEGVEAFHT
VLENDYPQSPEDLIEKIS----SYKQI------GISTLQAILEE--SNDYKSHYER-----------P---------KLST---DYVEPRTEMEKMLCKI
WSKIFGVEEIGINDDFLELGGDSLKALTAISQIHQVMGIRVSLPEFFKHPNIKEFSNFILER----------
>tr|A0A0J6BPS4|A0A0J6BPS4_BREBE Uncharacterized protein OS=Brevibacillus brevis GN=AB432_12610 PE=4 SV=1
--------------------------------------------------------------------RLYAEALRTCFELIGQDEYVEMPGALEGFSRP
FAL------DQAPLLRIRLVCVEKQ-RHVMIISDGLSSERFLAYYDGQTLG----DPKIQYRRPSIKNFAGSFVLADEKAALFGCFSILLAKYSGQNEIL
ILRSYPEGGKRVELVQQIEKER---DLSRNPLFDTMFTWEQRD------------RSQLIIHGRYDFHSGIARMGRHFQQIVDEILQSPIRLILREGFNQ
VVWEGYRFIIGLLA-IEKAGCAYLPIDPTT-PAERIQYMVEDSV-LSHAGLVGIANTAGVVVYDLVLTHGGMTNRLRWMADQYGMDDKEVVLIGGDDYNL
ICEQEVPSMLASFSRRCICSGEELSIEDVSYYEVQEEDQLIPIGEGGFAPIGVPGQV-------AKGYLNRPELTAETGDLARWLEDGNIAYLGRKGFRI
ELGE-IESAYTDQIETVAVLFSAKDKI------DTGKLKTHLQRH-LPAYPVHYQRKA--------LPH-------ITVSD---NIEKPRRKEGQLLVSI
FKETLNIENLSSTDHFFELGGNSLAAIVLKSKISAAFQVQLTMQEVFEHPTIRELVPLILQK----------
>tr|K0UK51|K0UK51_MYCFO Non-ribosomal peptide synthetase PstA (Fragment) OS=Mycobacterium fortuitum subsp. fortuitum DSM 46621 GN=MFORT_25954 PE=4 SV=1
--------------------------------------------------------------------RLWFESLRTVFDAPGGIGWDVVDATEHAVNEA
VDVRYAFDLSSEIPLRANLFRVSDH-EHVLIAADGWSLSPLSVAYASRSRG----QAAVQYPYPPVADQLGSVDWPAELQQMQAALAVLLSKLGATSDVA
VLRVDLDGDPTVVLVERINPAR---SLTRHPVVQVALAWQNLPWQD----TGP--ADGLSLGDPLPVETQTAALVARWQRVLAAMTADPLDLLMDAWGHR
ITADGYRKVVAMLA-VLKAGAAYLPIDPVL-PDARIEFMLEDAA-IVTTGLADRLAGCELLIVDVVITHRNVTELLGTPD---TFMAGQTWTHGGSEQAL
LAAEQVPSASPERLTTLLVAGEPCPADCASRTALAAGSGAPPIGSLRQVPAGVVGGV-------GLGYVGRTGLTGSTGDLVSWGADGQLHYVGRAGYRI
ELGE-IQSGLDGVDQAAVIAVTGTAEPG----K----LRAQLAEQ-LPAYPAAVVTRA--------LPA-------PEYQDI-DNYRAPSTPTEEILTEI
YARVLGVERVGVDDSFFDLGGDSLSAMRLVAAVNTALDTGLAVRVLFEAPTVAQLAPRVG------------
>tr|X8DM27|X8DM27_MYCCH D-alanine--poly(Phosphoribitol) ligase, subunit 1 OS=Mycobacterium chelonae 1518 GN=dltA PE=4 SV=1
--------------------------------------------------------------------RLWFESLRTRFDAPGGNGWEIIDATTGQLDEA
IAVCRSFDLAIEIPLYARVFRIAEE-EHVLIAADGWSLTPLSVAYASRCRG----HAPVQYPYPPVADQRGSVQWPPELQQMQASLAVLLASISGTSDVA
VLRVDLSGDPTVVLVERLNPIR---SLAHHPLVQVALAWQNLPWQD----TGP--ADGLRLGDPLSVDTQTAALIARWQRVVASMTADPIDVLVDRWGNR
ISFNGYRRVVAMLA-VLKTGAAYLPIDPAL-PDVRVEFMIGDAA-ITTADLTDRLAGYALTVIDVVIAHHNVTALMGSPA---TFLAGHTWAHGGSETAL
LVAEQVPSATPESLDSLLVAGEPCPGECASRTALVGGTGSPSIGLLRPVPPGVVGGV-------GVGYAGRTGLTASTGDLVRWRADGQLEYLGRAGYRI
ELAE-IHSALDGVDQAAVIAVTGTANPA----K----LRAQLAEQ-LPAYPVAVVTRA--------LPR-------PEYQDI-DRYRAPGTLTEEILAGI
YARVLGVERVGVDDSFFDLGGDSLSAMRLIAAVNADLNAVVSVRTVFEAPTVGQLAPRIA------------
>tr|B0JJW9|B0JJW9_MICAN McnC protein OS=Microcystis aeruginosa (strain NIES-843) GN=mcnC PE=4 SV=1
--------------------------------------------------------------------RLWFEALRTNFITVDGITV--VDLQAIASQEL
AQAIQPFDLAGEPLIRITLVVLSET-EHLLIVSDGWSMGVLTALYNAYIQG----LSSIQYPRPNQQSFAGGFSLSWELTELLTAYAVLLYRYTEQEDIL
ILRIDLSGKPNFMLVEVLQPER---DLSHAPLFQVDFLLQNSPPS------------PLELTGPLTTENDTARLTGNFITLLEALVVNPLPLLLLKDWNA
VVFEGYQYIVGLLA-VLKAGGAYIPLDPDY-PQQRLTYMAEDAL-LTQESLLDSLPAEDV-GVIVVLTHEALVNHSWGISEVFGLTESDRVLKGGTTADF
IEQESLPAYATVPSSVVAVGGDAVLPETAIVHD--EKINSVLIGNLQPVPIGVKGRL-------ARGYLNRPELTAETGDLARYLPDGNIECFGRIGFRI
ELGE-IEAQNIDVQTSCVIIIVAHYERI----PMISELRQFLSSK-LPLYPQAFVRRA--------LPA-------PDKIGNRDQYVAPRNGIEEMLVQI
WTEILKIDQVGIYDNFFEIGGHSLLATQLVSRIRSLFKIELPLRSLFGAATVAELAHLIGQL----------
>tr|R9VGH3|R9VGH3_PSEPU Uncharacterized protein OS=Pseudomonas putida H8234 GN=L483_23455 PE=4 SV=1
--------------------------------------------------------------------RQWMESLRTVFEEHDGIEF--HDLS-RALQQR
IQALTPFDLEQGPLIRVKVFQGGPQ-EQVLIVSDGWSMSVLAGVYNAHTTG----QPAVQYIRPQAQSYRGGVLLPAALTAFLASFALLLSRYSGRETLN
IARVAVDPLQSFVLVEALKPER---GLGHNPLFQVMYNHLSILGER---------VSGDSVQGEVELVEHTTRLASVWVNLLGALASEALPLLAAQAVDP
LVLDDYQKVVGLLG-ILKAGAAYVPLDPQY-PQERLRFMMQDSL-LTQPHLTPTLPIPPAVTCLQVVAHRELSVFCSVAADYSRLDASDRVLCGA-EQQA
IVTHGITAYAGACASQVHVGGEAMPMEVTTVQDGAGGKAIVPIGGLALAPVGWVNCL-------ARGYFNRPGLTAETGDLASYRVDGVLDYVGRIGLRI
EMGE-IEAEHAMVREAQVIDLVIEGGVEQQ-DALRENLASHLKAA-LPDYPAHLMRKA--------LPK-------PDLGRDQPAYVPARSERERQIAAI
WAQVLKVERIGLTDHFFELGGHSLLATQVTSRIRQVLGLEIPLRTLFEAPVLADFVA----L----------
>tr|E1TCG1|E1TCG1_BURSG Amino acid adenylation domain protein OS=Burkholderia sp. (strain CCGE1003) GN=BC1003_2219 PE=4 SV=1
--------------------------------------------------------------------SLWFPALRMRFGEVEGVRVLELPCTSEALADC
LVVRKPFDLMSEPPVRATLVRVADD-QHVLIVSDDWSIGLFSRLYRERCAA----GASVDYVRGGARRAAGATRVPAATTKLLAAFDALLYRYSGQSDIR
LIRTAPRGAMRASVVKAVQPER---ELTHTPLFQVLVNQQQRHDLT----T-------SFGDEVQEVDSGEARIARHFTRLLEQWSSAPFELP-------
LVDGNYAEVASLLG-VLRAGAAYVPLDPSY-PAERLAHIVDDSV-VTDAESLAQHAALDAAALRDVVTHENVARLFDATQSRFAFNEKDVWTHGAEAHAL
LCEQQVPSATNTLDSAVIFGGERLEPAHVTHRTAALREARSVIGDLNRVPVGAVGGL-------ARGYLGRAALTAQSGDLARRLADGDLEYLGRNGFRI
ELGE-IQAAHPEVRDAAVLVVVPRGAPHT--DD-VARWQAWLAAR-LPAHPSSYVRRA--------LPA-------PEAVAHAAQAVAATTPAESALLVV
WRAVLRRDDIGVTDNFFVIGGDSILSMQIVSKARD-AGLHVTPRMVFESPTVQQLARVARAL----------
>tr|A0A0A0WVD4|A0A0A0WVD4_9BACI D-alanine--poly(Phosphoribitol) ligase, subunit 1 OS=Bacillus weihenstephanensis GN=dltA5 PE=4 SV=1
--------------------------------------------------------------------RLWFESLRTVFHEVNGQPK--TDLTEEEVKRL
IQTEMPFDLGEGPLIRTSILQVGEE-EWILIISDGWSMGVWMAFYEKTTDG----KVPVQYPRPAIQTHDGSLVLPSSLHDLLAAYQSFLSRYTGQEDIL
VYRANLSGRPTFKIVEVVQPER---STSHSPIFQTMFILQNMKQE------------FPVLSGMIESHSPIARMAGHFEKWLHEVSHYPLSMLLLETWND
VVDQTYGVMVSLLG-ILKAGGAYVVLDPLY-PKSRLEYMIEDAV-VTAEGQEGLFEQVEMVRLEEVIEYRSLMNMVSWHQEVYRITAEDRATAGANERDW
LIDSRITPILPGKTDFIITGGDQL---VTTD--VGVTTGTPSIGHLQLVPSGVIGSL-------ARGYANRPDLTKETGDKASYLSDGALQFHGRIGFRI
ELGE-IEAAHSSVKEAVVLVVVGEGSVQ----E----WREHLQTH-LPNYPTNFILKA--------LPI-------PSKLSTENT-FHARTPLEELIASV
WSQVLGIENIGVQDSFFELGGHSLLATQVVSRLQEVFQIKLPVRELFEYSTVEALAKRLDQL----------
>tr|A0A0M0T6H8|A0A0M0T6H8_9ENTR Polyketide synthase OS=Xenorhabdus sp. GDc328 GN=AFK69_16885 PE=4 SV=1
--------------------NISEWLYGEIWQDALLPNKSQSDVKMALCFVPDIEWCEPLRHMNIDEKAVRFVLSGDNYTTAN-NVITLSAGEVSHFERL
FNELKENQLQPDSIIFAWPLSGSDE------V----KNTWFSAITLLQAWTT--VGNMCDF------RLLLVNTEQPESNMLNGLVKVITQEVSKCHPRL
VQINPTESI---EKNCEILTEELLATGERFIVRRKEGCSKQAYERIA--INPLKEHSLLKPQGIYLITGGLGDLGLLFAEYLLKEYRATVILSGRRELPD
QREWKQEILQRLDKLSDLGTGNLAYYAANVADKSAMQRLLTTISKQYG-ELNGIICAAGVTEGNSINRITLDACLPQLETKVEAYKILAELTENQPDFCL
LCSSIA-VVLGGLSFSAYSSVSAFADSFAKQQS-KKGKPWISVNWDGWVFERNDSGDALGSSLSQ---LLIEPDEGIK--------------V-LER---
VLQSPLRD-------QIIV---STGDLDKRFAQ-------WV-----GS---YLKTFDINKVN---QSQRKTI------S---------KAQIVETILSV
WKDFLKIAHINREDNFFELGANSLDLVQVNKRLTDALNIDISVVDMFSYPTSDLLADHITNQ----------
>tr|A0A077Q7N9|A0A077Q7N9_XENBV Polyketide synthase involved in xenocoumacin synthesis OS=Xenorhabdus bovienii str. Intermedium GN=xcnF PE=4 SV=1
--------------------EISEWLYTEAWEDISLPDETQSDIRVALCFVPDITWCQPLNSLKLEEKSIKFVLPADAYTSAE-NVITLVPGDKRHFGKL
IDELKQDALLPDSIIFAWPLSGQSD------L----ETSWFSVITLIQSWTT--SGSMTDF------RLLLANTKQPEHTMLNGLVKVITQEVSKCHPRL
VQISPLESI---ARQCEILTEELLATDERFIVNRQTGRSTLAYHKLK--AGLLKENTLLKNEGVYLITGGLGDLGLLFAEYLIKEYGAKVILSGRRALPG
KHEWKHEILQRLDELSELGKGEVAYYSSNVSDKHEMQALLDAIEEQYG-CLHGIICAAGVTRGNSINKLTLEDCTPQIETKVEAYQILAELTENKPDFCL
LCSSIA-SVLGGLSFSAYSSVSSFADAFAKQQN-SQGKPWISVNWDGWVFERNNSGDPIGSSLDQ---LLIEPDEGLK--------------I-LEC---
ALQSPLRG-------QLII---STGDLNKRFEQ-------WV-----GG---HLKPFKLNEFN---HSQRAVV------S---------KAQIVGTIVSV
WQDFLKVTNISRDDNFFELGANSLDMVQVNKRLTDALDMDFSVVDMFSYPTSELLADFIVNQ----------
>tr|D3VCB3|D3VCB3_XENNA Polyketide synthase involved in xenocoumacin synthesis OS=Xenorhabdus nematophila (strain ATCC 19061 / DSM 3370 / LMG 1036 / NC
--------------------TISDWLYGEIWQDALLPDKNQSEVKTALCFVPNMEWCEPLRHLNVDEKSIRFVLSGDDYTSVN-NVITLAAGEVSHFEKL
FHELKENQLQPDSVIFAWPLSGHRD------L----KNTWFSAITLLQAWAT--IGNMGDF------RLLLVNTEQPESGMLKGLVKVITQEVSKCHPRL
VQINTTESI---ENTCEILTEELLATDGRFIVCRDGRCSEQVYERLN--VEPQKKHSLLKQQGTYLITGGLGDLGLLFAEYLLKEYQATVILSGRRELPD
RHEWQQNLLQQLNKLADLGRGNVVYYPANVADKSAMQRLLQTIDEQHG-VLNGIICAAGVTEGDSINRITLDACSPQIETKVEAYKILAELTEHQPDFCL
LCSSIA-SMLGGLSFSAYSSVSAFADAFARQQN-QQGKPWISINWDGWVFERNDSGDALGSSLSQ---LLIEPDEGIQ--------------I-LER---
VLQSPLRG-------QIIV---STGDLNQRFEQ-------WV-----GS---HLKAFDINKIS---KSHRKTI------S---------KDQITETIISV
WKDFLKITQINREDNFFELGANSLDLVQVNKRLTDALDIDISVVDMFSYPTSELLADYITSQ----------
>tr|A0A022PKQ8|A0A022PKQ8_PHOLU Polyketide synthase family protein OS=Photorhabdus luminescens BA1 GN=BA1DRAFT_01898 PE=4 SV=1
--------------------ELTQWLYTEQWQPIELPTETEQ-ANNIVCFVPSLAWCNVFKRFNQEGQKLKFIVPSPEYYVDG-QVIGVTPGDKNSFNKL
MAELAHSCFSPDSIIFAWPLSGTKD------I----MTSWFAVILFLQSWGK--SGHLSEF------RLLLATTALSEHSLLNGLIKVIAQEVTKCHPRI
IELDTDESI---EAACDILAQELTASDMRFIVKRQQARFEKRYQQLE--NNEQAKKQPFKKQGVYLITGGLGDLGLLFAEHLVTQYGAKVILSGRRDLPR
KAQWGDKLIDRIHQLSLMSEGDIDYYAADVCDRQEMETLIGHIEAQYG-QLNGVICAAGVTRGDSINHITMENCQPQFDTKVYSYQLLAELLEHKQDFCI
LCSSIA-AILGGLSFSAYSSVSSFADAFAKQQN-QLGKPWISINWDGWVFERKDANDAIGSSLEQ---LLIEPDEGLY--------------I-LER---
VLQSPLEA-------QLIV---STGDLNKRFEQ-------WV-----GT---HIRPFTNQSHS---AHSRQIF------S---------KQQIVDTIMDI
WQDFLKIHSINSGDNFFELGANSLDLVQVNKRITEALYIDLSVVDMFSYPTSELLAGFIIEQ----------
>tr|W5U3K4|W5U3K4_9CYAN Polyketide synthase OS=Moorea producens JHB PE=4 SV=1
---------------------YGDWLYEIAWRPKDIDASDVDISTTWLIFADQGGFGETVGKAVPKEHRVLLISRGSSYEQLQANHYQINPAQPQQFQRL
AQQVESLTATSVIVVHMWSLDTPAVDGQTFPLDVTLENGCGSVLHLLQALVKAELSPRLWLLTQGTQPVGKEKSLRIAQSPLWGLGAVIAQEHPELWGGI
IDLEPSQDLSYQEQSLMVLKQILRPEGENQLVLRDRQTYVPRLI--HQQQSQLASSPLQKPDSTYLITGGLGSLGLKVAEWMVDKGARYLVLVGRSQPNP
ASE----IIEKLE----EQGVMVVLEQVDVSQEAQVRDCLNRIQVSL-PPLKGIIHGAGVLEDGVLLHQDWAKFAKVMKPKVEGAWNLHLLTQDIALDLF
VLFSSATSILGTPGQGNYSAANRFLDSLSHYRR-QQGSPALSINWGPWAEMGLAAGVG--KRMTMLGIEPIQSPQGLQILEQLLAQDVAQVVLPVEWSTL
KQRLPVEL------------------------------PLFLSEV---------ITTETLPPQGDGENDNSGIFDQLLAS--------TTAQREELLKDY
AKALGISREIPVESNLMDLGTDSLMIVEVLNSCKKDLKITLYPREFYERPTITALAEYLALE----------
>tr|W5U986|W5U986_9CYAN Polyketide synthase OS=Moorea bouillonii PNG5-198 PE=4 SV=1
---------------------YGDWLYQIAWRPKDVDSSDIDISTTWLIFADKEGFGER--------QKVLLISPGSSYEQLQPNHYQINPAQPQHFQRL
AQEVESLNATSVIVVHMWSLDTPALDRQTFPLDATLENGCGSVLHLLQGLVKAELPPRLWLVTEGTQPVALEKSLQIAQSPLWGLGAVIAQEHPEIWGGI
IDLEPSQDLNYQEQSLMLLNQILQPQGENQIALRDGQAYVPRLI--HQQQSQPPALPLQKPDSTYLITGGLGSLGLKVAEWMVDKGARYLVLVGRSQPNP
ASE----IIGKLE----EQGVMVVLEQVDVSQEAQVRDCLNRIQVSL-PPLKGIIHGAGVLEDGVLLHQDWAKFARVMKPKVEGAWNLHRLTQDIALELF
VLFSSATSILGTPGQGNYSAANGFLDSLSHYRQ-GQGASALSINWGPWAEMGLAAGVG--KRMAMLGIEPIQAPQGLQILEQLLAQDGAQVVLPVEWSKL
KERLPVEL------------------------------PLFLSEV---------ITTETLPPQGDRENDNSGIFDQLLGS--------TTTQREELLNDY
AKALGISREISGSSNLMDLGADSLMIVEVLNACKKDLKITLYPREFYERPTITALAEYLALE----------
>tr|A0A023XMC6|A0A023XMC6_BRAJP Polyketide synthase OS=Bradyrhizobium japonicum SEMIA 5079 GN=BJS_00720 PE=4 SV=1
-----------------------------------------DRAASWIILADSNGVGAALLEVLGHHAHLVHRSDG--FVQRGPRAWTANERDPQDFRRL
LAQLA-ETEALPGVVYLWGLDAPSINLTFRRLKSASERGALAILHALVEMRSKRPVGRLWFVTTNTQSPAGQWPVDPAQAPLWGLGRTIAIEHPGLWGGL
IDMQLG--D-RGFDANLLAAELLDPDGETQIALSTRQRYVPRLVEQSMA-ELPARPPVIRTHATYLVTGGLGMLGHSVARWLIAKGAKHLVLTGRHASPE
VAR-------ELFNNAELNAADIQVVAADISREEDVKRLLQT--IKELPPLRGVVHSAGVLDDGILAQLDWDRFAALFEPRVYGGFLLHEHTKSLEDFFI
L-KSSLLSLLGSAGQANYTASSTFLDSLAMHRR-VTGLPAMVINWCAWSEGGLATLSRGEAMLSSWGMKFVSPDLGIRLFDLMMRRNVD-----------
-------------QVAVVDADWPTFVSKVGMPRFLSLVNTAVEPRRPG----HVALASTAGRKANG---------------------KSREQLSRRLHQQ
IREEGFVEDIDPDLPLNEIGLDSLMSVSLSNSLERKFGIPVPIAQLIRGPTINQLIAS--------------
>tr|V6JQ84|V6JQ84_9ACTN Uncharacterized protein (Fragment) OS=Streptomycetaceae bacterium MP113-05 GN=N566_27610 PE=4 SV=1
--------------------------------------------------AS--GSGEPECVLVGSDALGIAE----------P--LTEAGVPVESFAAL
TGAVS-TGMTLPVLVALDGSDAPDGLPRAARETTAHA---LR-TARTWLADDRLAGSRLAFVTRTAVGTGSDRPGDLAAAPLWGLLRSAQSENPGRFA-L
VDLDEQ--P-DS--VLALPAALDTR--EPQLAVRGGQVHAARLARVPVPA---DPAPAWDPDGTVLVTGATGALGGPVARHLVEHGVRHLLLLSRSGTAS
ERGA------ALRDELAALGAHVTLAACDAADRDALAATLAD--VPDAHPLTAVVHLAGVLDDGVVSALTPERLDGVFRAKVDAALHLHELTRDTPAAFL
L-FSSSAATFGAPGQGNYAAANAFLDALAEQRR-ADGLPALSLAWGAWEQGMAGRLDTDRSRMARGGVLALSETEGLALLDQTLHSADA-----------
-------------ALVPVRLDLAAFGP-----ELFRLVRRSARRATAAT-----------GEQAGPSLAQRV---------RGLDAAGSRTAVLETVRAA
TAAVGSGEDIAPDAAFLELGLDSLTSVELRNVLAAVTELRLPATLVFDHTSPLDLADH--------------
>tr|J3AWZ5|J3AWZ5_9BACL Beta-ketoacyl synthase family protein,phosphopantetheine-containing protein OS=Brevibacillus sp. CF112 GN=PMI08_04780 PE=4 SV=1
--------------------------------------------------------------------RLVTVELGARSAQVAPDYFQVS-RTLDDIAAF
CAQL---DLASLAQIVFMPPARAALPESLAAFRSAMDQTAGSLLLFAKALAT--TGKNEIDVVLLTQNAQAVQPGDAACDPLGGLGKSLRQENYGLSVRH
IDISPD----GFAP-EPLFAELGRKGTDYSVALRQNRRYIEIIERAKQTGAQED-SFAIEAGDVFLITGGLGQLGTEVCKYLSQKNKVKLIVLGKTMRET
WLRE-SPDISLADKIVEALGSTLDYHCADICDEAQLQRTVQAIRQTH-QRLAGVIHCAGIGVGELESALGEAEFARRHAVKTDGSWLLYTLTQEIDTGFY
LFFSSAVSVTGGRGALGYATGNAFLDGWAEAIR-RQGKKVFSINWATWEETA-ERLSMQE---ERHVFRFLPTHQALQALDSILR---------------
--RQMFR---------TIVGQFN--QAN-----------------------ELLELAHIWPFRLADEVKKDVFRQTAKPGRVPVTLKEQDTATQKELAQV
WAEVLGLSSISLFDSFHQLGGDSIHAAQLYKQWNEKYPGTLHVADLYLYPTIFEMANYLDGK----------
>tr|A0A0E4H817|A0A0E4H817_9BACL Beta-ketoacyl synthase family protein,phosphopantetheine-containing protein OS=Paenibacillus riograndensis SBR5 GN=PRIO_1742 PE
--------------------------------------------------------------------RCILVEIGRPYRKINAEHYHVS-NSVEDFSAL
CGEL---DISALEQILYAAPSREGLPDSLKEFKESFNQTVMNLLYLVKALQA--ANTKDLDIALITRNAHVLQPMDTGSDPLYGIGKSILQENRSFHVRH
IDISNE----PADL-EALPAELEVPSAQYSVALRHGRRYVEVIKRADIAEQAGE-AIAIEAGDTFLITGGLGLLGIEVCKYLSQKNRVKLIVLGRTARES
WIMD-NEDKQLLKKIIEALGFTLDYHCVDICDEAQLRRTVEQIRQDH-GSINGVFHCAGVGVGDIEFGMSGQEFEQRHAVKTYGSWLVYNLTQEFNTGFT
LLFSSAVSITGGRGSLAYTAGNAFVDGLAETIR-LQGKNVMAINWSTWEATA-SRLSLQA---DKHFFEFLSTHQALQALDLIIR---------------
--RGMFR---------TIVGKLN--VQN-----------------------KLLELENLWPFRLAGEIKQALFPKTRQEERTSVTVKEPETATHRELAQV
WADILGLTTISVFDSFHQLGGDSIHAAHLHKQWNERHPGTLDVTDIYRYPTIHEMAGYLDSQ----------
>tr|A0A089M5F9|A0A089M5F9_9BACL Beta-ketoacyl synthase OS=Paenibacillus graminis GN=PGRAT_08135 PE=4 SV=1
--------------------------------------------------------------------RCILVEIGRPYQKITGTHYYVS-NSAEDFSAL
CGEL---DISALEQILYAAPSRDGLPDSLEEFKDSFNQTVMNLLYLVKALQA--ANSKNLDMALITQNAHVLQPMDTVSDPLYGIGKSILQENRSFHVRH
IDISHE----PADM-DSLLAELEVPSADYSVALRHGRRYVEVIKRADMAEEASE-AAGIEAGDTFLITGGLGLLGIEVCKYLSQKNRVKLIVLGRTARAS
WIME-NEDKQLLKKIIEALGFTLDYHCVDICDETQLRRTVQLIREHH-GRINGVFHCAGVGVGDIEFGMSEQEFEQRHAAKTYGSWLVHQLTEPFNTGFT
LLFSSAVSITGGRGSLAYTAGNAFMDGLAETIK-LQGPNVMAINWSTWEATA-SHLSLQE---DKHFFEFLSTHQALQALDLVIR---------------
--RRMFR---------TIVGKLN--VRN-----------------------KLLELENVWPFRLADEIKQTLFTKTHREEQTRVTVKEPETATHRELAQV
WGDILGLASISVFDSFHQLGGDSIHAAHLHKRWNERHPGTLDVTDIYRYPTIHEMAGYLDSR----------
>tr|A0A0J6BUC2|A0A0J6BUC2_BREBE Beta-ketoacyl synthase OS=Brevibacillus brevis GN=AB432_12575 PE=4 SV=1
--------------------------------------------------------------------RLIMVEIGTHSLQVTHDHFKVA-RTYEDISGF
CAQL---DISSLDQILFIAPTTHDLSESWIEFQSSMNQTAGSLLLFTKALHM--TGKKEIDVALITQNAQAVQMAVAICNPLVGLGKSIRQENFCLNIRN
IDCSSD----NLEL-DLLLAEIQRKSTCYSVALRQGRRYIEVIQKADVSGTQED-ETTIGAGDVFLITGGLGQLGTEVCKYLSQKNKVKLIVLGRTMKEA
WIRE-QSDKDLMNKMVEALGSVLDYQCVDICNESEMKRLVQNIQETH-GQLNGIIHCAGVGVGDIEFGMSEQEFERRHAVKTYGSWLLYTLTKEMNKGFT
MFFSSAVSVTGGRGSLSYATGNAFLDGLAEAIK-RQGKKVISINWATWETTA-SKLSMQE---ERHVFRFLSTHQALQALDHILH---------------
--RQMFR---------TIVGKLN--HAN-----------------------ELLELEHVWPFRLADEVKQELFKETAKPGRTSVTLKEKDTATQKELAQL
WAEVLGLTAISLFDTFHQLGGDSIHAAQLYKQWNEKYPGTLHVADIYMYPTIYEMANYLDSK----------
>tr|M3BCW6|M3BCW6_STRMB Beta-ketoacyl synthase (Fragment) OS=Streptomyces mobaraensis NBRC 13819 = DSM 40847 GN=H340_26666 PE=4 SV=1
--------------------EYHDSLYRVDWTPVPSPARVP--AGT----WTVVGPEASWTRVLAAADASAPVLPDAG----AADVVVLPAGTEDAGGDA
AGAARERTHRVLADLQSWLADERF---------------AGSTL------------VVVTRGAA---PAGTTEVTDLAGAAVGGLVRSAQAENPGRIV-L
VDTDGTD----ASLA-SLP--RALAAGEEYLAVREGELSVPRLARVPATVRTADADETRDGHGTILVTGATGALGALVARHLVAEHGRHLLLASRRGPDA
--PGAQELGAELA----ESGAEVTFAACDIADRDRLAALLDSVPA--EHPLTAVVHVAGALDDGVIGSLTPDRMDTVLRPKADAAWNLHELTRGLDLSAF
VLFSSVAGALGVPGQGNYAAANAFLDALAHHRR-AAGLPATSLAWGMWADSGMAGGLADVRRMARSGAGALSAKEGLALFDAAFTGSEALLPVALDLRLL
ADPGEL--------P-PLFRGLVRTT----------------ARRTRSAQ--------E---PSAGTGD---LLARLAA--------TPAAERRLLTEVV
RAQVLGHDGVDADRSFNALGFDSLTAVEFRNRLNAATGLRLPAALTFDHPSSRAVADHLWDE----------
>tr|D9WQ71|D9WQ71_9ACTN Modular polyketide synthase OS=Streptomyces himastatinicus ATCC 53653 GN=SSOG_05745 PE=4 SV=1
--------------------ERRDTLFRVDWAPLAAASESA--PTR----FAVVGGDDLLSVALDAAGATMAVVMDGT----APDTVLIPF-LPDGGDDL
VADAHAATHRALGLVQEWLNGGRP---------------DGARL------------VLVTRGAVA--AAGDTEVADLVNAPVWGLLRSAQTENPGQFV-L
LDVDGEV-----SYP-AIA--AALDSGEPEIALRAGAAYAPRLAWVEAP----ADENTLDPEGTVLVTGATGGLGRLVARHLATAHGRHLLLTSRSGPAA
--EGMAELVAELA----TLGAEAAVVACDAADREALAGLLAGIPA--DRPLTAVVHTAGVLDDGVIDMLTPERVDRVLRPKVDAAVNLHQLTRDLDLSAF
VLFSAAAGTIGGAGQGGYAAANVFLDALAGHRR-ATGLAAQSLVWGMWAERGMGGRIADLKRAARGGVLPLSAEEGLALFDAARTVTEAVLPVRLDLAAL
RSAGEL--------L-PLYRGLVRTP----------------ARRADGGG--------PAVESAAETDT---LAQQLAR--------QSEAQQETVLDLV
RRQVLGYEQVGAEQAFKELGFDSLTAVELRNRLNTATGLKLTATLVYDYPTPVALARQLRHE----------
>tr|A0A0A2KKH6|A0A0A2KKH6_PENIT Acyl transferase/acyl hydrolase/lysophospholipase OS=Penicillium italicum GN=PITC_009190 PE=4 SV=1
--------------------STSGLVHQISWPPATLVEEPLKFLVP----DATNTHVETYQRQLQSRDTS----PLTT----HSSLAIVYLP--QVTDQI
FETATSTCNGLVSAAQVILSFSNN---------------PTVRL------------FTLT------------SENNLGHSALTGLGRILHTEHPEIWGSL
IDLEDPS-----IFP-LMA--MRYVRNADVIKIQDGVPRTACLRPLRSAPLH----LTFSPASTYLITGGLGCLGLSVAQWMVGQ-GRRILLLSRRSLPP
RTQSIIQSILSLE----RLGATIHSLTIDISHPSAVINLRSALATLNLPPVAGVVHAAGILRDQLVEQITPEAFEAVLAPKIAGALALHAVFPPNSLDFF
VLFSSCGQLLGFPGQASYASGNSFLDALARSRR-KEGDNSISLLWTSWRGMGMGASSALEAELYARGITDVTPDEAFRAWSSISAS-HGVVRARP----L
ESGEPV--------PHAILRGIVTRK----------------QRV-NEVT-----------------GE---GGEQRKK--------LTGTELAYLRVAV
KKCTLSIDEVDETVALPEMGMDSVMTVNFRMSLQQTLTVSVGPTLVWKYPTVHHLVEYFSQV----------
>tr|A0A0P4U843|A0A0P4U843_ROSNE Putative 6-methylsalicylic acid synthase OS=Rosellinia necatrix GN=SAMD00023353_2900860 PE=4 SV=1
--------------------STNGLVHRIAWVPAPFAETPLAFLVH----DSIPGYILDHEEHVVAKGTS----QGLS----STSIVIHFAH-DSTIEGI
AAAASGSCENLVSAAKVMAAS--G---------------STGRL------------FSLIDQT---------YCSALGSAPLYGLSRIMKSELPHIWGGL
FELEKHT-----TFP-LTG--LKYIQGQDVVRYEDDIARTARLRPFPEAGPR----DLVHPSGTYLITGGLGALGLETARWLCAS-GRRLILVSRRKLPP
RSWEILRRITELE----NIGASVHVIAVDISKANADVSLAEAIDNLSLPAVRGVIHAAGVLYDQRIEEITKEAFDSVLAPKINGALHLDRLFPPGSLDFF
TLFSSCGQLLGFPGQASYASANSFLDALAERRR-SRGDNALSILWTSWRGLGMAASTYINAELEARGISDITTEEAFMGWERLFHL-HGVIRALA----L
DSDEQP--------PHTILQDIATRR----------------PAA-VGRD--------AG--QRSSSPG---NARGQRP--------TSGHELEYIRTAL
TSATLGIPHVDPSLPLSEMGMDSVMTVSFRTKVQKSLKVKMAPTLVWKCPTLDHLVKHFMTV----------
>tr|G3Y419|G3Y419_ASPNA Polyketide synthase OS=Aspergillus niger (strain ATCC 1015 / CBS 113.46 / FGSC A1144 / LSHB Ac4 / NCTC 3858a / NRRL 328 / USDA 
--------------------STAGLVHQIQWPPAALVEDPSEFVTP----DITDPRLEQYQSQLDALASS----PLTS----HTSLAVVYLP--QTMTDV
FDTATRSCNDLVSIIQTITA-AAS---------------STTRV------------FVLT------------AGTELGHSALLGLSRIIQAEHPDIWGSL
IEVEDTF-----SLP-LMA--MRYVRDADVIRIKDGVPRIARLRPLPSAS------LTFSPASTYLITGGLGALGLSVAHWMVTQ-GRRLLLLSRRALPP
RNNPTIQSILALE----RLGATVHCLPIDISLPMAASGLRSTLETLNLPSVAGVIHAAGIVSDQLVEQVTPDVLESVLAPKIKGALNLHDVFPPASLDFF
VLFSSCGQLLGFPGQASYASGNAFLDGLARSRR-AQGDNAISLLWTTWRGMGMGQSAAMEAELYARGITDITPDEAFRAWSAVASTGHAVIRARV----L
EGGEPL--------PHPILTDIATRK----------------AEV-NAGE-----------------HP---AGSQEVK--------LSGRELEHLRDVI
NGCTLSVDEIDDAVALAEMGMDSVMTVNFRMTLQQTLKVPVGPTLIWKCPTVQHLVKHFTKE----------
>tr|P87001|P87001_PENPA Putative polyketide synthase OS=Penicillium patulum GN=pks2 PE=4 SV=1
--------------------NTSGLVHQISWPPAALVEEPLEFLAP----DAATTYVETYQMQLESRGTS----PLTA----HSSMAVVYLP--QVTDQI
FETATSACSRLVSAAQFILSFSKK---------------PTVRL------------FTLT------------SETNLGHSALTGLGRILHTEHPEIWGSV
IDIEDPS-----VFP-LMA--MRYVRNTDIIKIQDGVPRTACLRPLRSTPLH----LTFSLASTYLITGGLGCLGLSVAEWMVTQ-GKRILLLSRRSLPP
RTSSIIQSILSLE----RLGATIHTLAIDISHPSAVVSLRSALTTLNLPPVAGVVHAAGIIHDQLIGQITPDVFDAVLAPKIAGALVLDTVFPPNSLDFF
ILFSSCGQLLGFPGQASYASGNSFLDALARSRR-KEGDNSISLLWTSWRGMGMGASSALEAELYARGITDVTPEEAFRAWSAISAV-HGVVRARP----L
ESREPL--------PHAILRDIVTRK----------------ERI-DDES-----------------GE---KEKQRNK--------LTGKGLAHLRVVV
KKCTLSIDEVDETVALPEMGMDSVMTVNFRMSLQQTLMVGVGPTLVWKYPTIHHLVEYFCQV----------
>tr|B6H6U0|B6H6U0_PENRW Pc16g00370 protein OS=Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255) GN=Pc16g00370 PE=4 SV=1
--------------------TTSGLVHQISWPPAALAEEPLEFLTA----DATKTHLETYQRLLKGRGTS----PLTT----HLSMAVVYLP--QVTDQI
FDTATRSCNDLVTAAQVILSFSDK---------------PTMRL------------FVLT------------SECNLGHSALTGLGRILHTEHPDIWGSL
IDLEDPS-----VFP-LMA--MRYVRNADVIKIEDGVPRTARLRPLRSAPPH----LTFSPASTYLITGGLGSLGLSVAQWMVTQ-GRRILLLSRRSLPP
RTRSIIDNILSLE----RLGATIHPVAIDISHPSAVTNLRSALTTLSLPPVAGVVHAAGILRDQLIEQITPDSFEAVLAPKIAGALALHTVFPPSSLDFF
VLFSSCGQLLGFPGQASYASGNSFLDALARSRR-KEGDNAISLLWTSWRGMGMGASSALEAELYARGITDVTPDEAFLAWSSISGT-HGVVRARP----L
ESGEPL--------PHAILMDIAPRK----------------ERA-DEGN-----------------GE---NGEQRKK--------LSGKELAYLRIVV
KKCTLSIDEVDETVALPEMGMDSVMTVNFRMSLQQTLTVSVGPTLVWKYPTVHHLVEHFCQV----------
>tr|K9GNJ5|K9GNJ5_PEND1 Nonribosomal peptide synthetase 7 OS=Penicillium digitatum (strain Pd1 / CECT 20795) GN=PDIP_42600 PE=4 SV=1
--------------------STSGLVHQISWPPAALVEEPLKFLTP----DATNTHVGIYQGQLESSGTS----PLTT----HSSLAVVYLP--QVTDQI
FETAINTCNDLVSAAQIILSLSNR---------------TPVRL------------FALT------------CEANIGHSALTGLGRILHTEHPEIWGSL
IDLDDPL-----VFP-LMA--MRYVRNADVIKIQDGVPRTARLRPLRPTPPH----LTFSPASTYLITGGLGCLGLSVAHWMVSK-GRRILLLSRRSLPP
RVQSIVQRILSLE----RLGATIHSLAIDLSHPCAVSSLRSALAILNLPPVAGVVHAAGILHDQLIEQITPEAFEAVLAPKIAGALALHAVFPPSSLNFF
VLFSSCGQLLGFPGQASYASGNSFLDALARLRR-REGDNSISLLWTSWRGMGMGASSALEAELHARGITDVTPDEAFRAWSLISAS-HGVVRARP----L
ESGEPL--------PHVILRDIVTRK----------------EQV-DGVT-----------------GE---VVQQRKK--------LTGTELAYLRYAV
KKCTLSIDEVDETVALPEMGMDSVLTVNFRMSLQQTLTVGVGPTLVWKYPTVHHLVEYFCRV----------
>tr|A0A0L8L359|A0A0L8L359_9ACTN Type I polyketide synthase OS=Streptomyces resistomycificus GN=ADK37_26615 PE=4 SV=1
----------------------RQPLYELQWRAARPGTPHTP-RTP----WGVLGTRHGAARLAEAGGTA----PAGR----APRHLVLCPD-PGTRPDL
LAAVATADKGVLECVQRFLAEDAL---------------APCTL------------VVLTRRAVD--TGAGDSVESLPGASVWGLIRSAQTEHPGRFR-L
VDIDDEE----TSWA-RLT--DALALGEDQLALRDGSCLVPRMTPAQPADHRLEPAGGGFGGGTVLVTGGTGGVGSLVARHLVAEHGRSLVLAGRRGAAA
--DGARELVADLE----AAGAVVRVVACDIADRAAVADLLADMPP--RYPLTAIVHAAGVLADGTVESLTAAGIDRVLHAKAGGALTLHELTKDHTLSAF
IHFSALAGTLGTAGQANYAAANAFLDALAAQRK-ASGLPGTSLAWGWWEQSGMTEDLADLLRLRRMGIAPMPTPEALALFDAAHALDKPLLPARVDVAAL
RGGDEL--------P-PLLRDLADGG----------------RPR-SRAD---------T-TKDGGFAG---LPARLAA--------LPGDEARAVLDWV
RDQVLGHAVVDTEQAFTQLGFDSLTSVELCNRLAAATGLRLATTLVFSYPTPRELGEHLHDL----------
>tr|A0A0N0A841|A0A0N0A841_9ACTN Type I polyketide synthase OS=Streptomyces sp. NRRL B-1140 GN=ADK65_31520 PE=4 SV=1
----------------------QRSLYEPHWRPARQGERETH-RGP----WGVLGAKDGAARLAAADGVV----LRTE----VPRHLVLCLD-PD----P
LTAAGDAGKHVLALLQRFLAEERL---------------AGSVL------------VVLTRLALD--TGTGQSVESLPGASVWGLVRSAQTEHPGRFR-L
VDIDDEE----TSRA-RLG--DALALAEGQLALRDGATLVPRLAPAAPADHRIEPAGDALGGGTVLVTGGTGAVGSVVARHLVAERGRSLVLAGRRGTAA
--DGVPELVADLE----GAGATVRVVACDVADRAAVADLLADMPP--RYPLTAVVHAAGTLADGTVESLTAESLDHVLAAKARGAVNLHELTRDRPLSAF
IQFSALAGTLGTAGQANYAAANAFLDGLAARRR-ASGLPGTSLCWGWWEQRGMTGDLADLSRLRRMGIAPMPTAEALALFDAACALDKPVLPARVDLAAL
RTGDEV--------P-PLLRDLAGGG----------------RPR-GRAD---------N-ARDGGSQG---LAARLAA--------LPADEAEAVLDWV
RDQVLGHAVVDVDQAFTQLGFDSLTSVELCNRLASSTGLRLPTTLVFSYPTPRELSEHLSGL----------
>tr|A0A0M8SU98|A0A0M8SU98_9ACTN Type I polyketide synthase OS=Streptomyces sp. WM6378 GN=ADK54_22380 PE=4 SV=1
----------------------EQSLYELQWRPAPQATPETG-RGP----WAVLGAHDGAARLAGAGDAA----LAGD----APRHVVLCLD-PD----P
LTTVATADKHVLDLVQRFLAEERF---------------GAATL------------VVLTRGALD--TGAGENVESLPGASVWGLIRSAQTEHPGRFR-L
VDIDDEQ----TSWA-GFA--DALALAEDQVALRDGACLVPRMAPAAPADHQLEPAGDGLGGGTVLITGGTGGVGSLVARHLVAEHGRSLLLASRRGTAA
--EGVAELVADLE----SAGAAVRVAACDVADRASLAAVLADMPP--HQPLTAVVHAAGVLADGTVESLTAQSIDHVLRAKVGGAVNLHELTRDHNLSAF
IQFSALAGTLGTAGQANYAAANGFLDGLAAQRK-ASGLPGTSLCWGWWEQSGMTEDLADLSRLRRMGIEAMPTAEALALFDAACAFDKPVLPARVDVAGL
RSADEL--------P-LLLRGLAEGG----------------RPR-NKAG---------T-AKDGGSSG---LFAQLVT--------LPADEAEALLDWV
RDQVLGHAVVDADQAFTQLGFDSLTAVELCNRLAAATGLRLASTLVFSYPTPRELGRHLLGL----------
>tr|A0A0F4KPL1|A0A0F4KPL1_9ACTN Type I polyketide synthase OS=Streptomyces sp. NRRL S-444 GN=VR46_00770 PE=4 SV=1
----------------------EQSLYALDWRPAPQAAPDAG-RAQ----WGVIGAETGAARLVAAGDVS----LTAD----APRHLVLCLD-GD---DL
LTTVGDAGKHVLETVQKFLAEDRL---------------AASTL------------VVLTRLAQA--TGAGDDVESLPGASVWGLIRSAQTEHPGRFR-L
VDIDDED----SSWA-AFA--DALALGEDQLALRGGTFLVPRMVQAAPADHRLEPGSSGFGGGTVLVTGGTGGVGSLVARHLVAEHGRSLVLASRRGTAA
--DGVPELVSDLE----GAGASVRVVACDIADRAAVADLLADMPP--QYPLTAVVHAAGVLADGTVESLTAESIDHVLRAKVGGAVNLHELTREHSLSAF
VQFSALAGTLGTGGQANYAAANGFLDGLAAQRS-ASGLVGTSLCWGWWEQSGMTGDLADLSRLRRMGIAPMPTAEALALFDAACASGKPVLPARVDLAGL
RAADEL--------P-LLLRGLADSG----------------RPR-SRTG---------T-PKDGGSVD---LAARLVT--------LPADEAEAALDWI
RDQVLGHAAVDADQAFTQLGFDSLTAVELCNRLAAATGLRLASTLVFSYPTPRELGLHLLGL----------
>tr|A0A0G3APC5|A0A0G3APC5_9ACTN Type I polyketide synthase OS=Streptomyces incarnatus GN=ABB07_39185 PE=4 SV=1
----------------------ERPLYEVRWRPVKEGERETR-RGP----WSVLGARGGAARLAGAGDAV----LAGQ----APRHIVLCLD-PG----L
LAAVGDTDQRVLDWVQRFLAEEPL---------------AAATL------------VVLTRRAVG--TGAGEGVESLPGASVWGLIRSAQTEHPGRFR-L
VDIDDAE----TSLA-RFP--DALALDETQLALREGALLVPRLAPAAPEEQRLQPEGDGLGGGTVLVTGGTGGVGSLVARHLVAEHGRSLLLASRSGEAA
--DGVPELVADLR----GAGAVVRVVQCDVADRAAVADLLADLPG--RYPLTAVVHAAGVLADGTVESLTAQSVDHVLRAKAGGAINLHELTRDHTLSAF
IQFSALAGTLGNAGQANYAAANAFLDGLAAQRR-AAGLPGTSLCWGWWEESGMTGELADLNRLRRTGIAAMPTPEALALFDAACASGKPVLPARLDLAAL
RSGAEL--------P-PLLRDLVDGG----------------RPR-ATAG---------T-AKAGGAQD---LAAKLAA--------LPADEARAALDWV
REQVLGHTAVDIDQPFTLLGFDSLTAVELCNRLSAATGLRLPSTLVFSYPTPRELSEHLCGL----------
>tr|X2CV18|X2CV18_9ACTN Putative type I polyketide synthase OS=Streptomyces sp. MK498-98F14 PE=4 SV=1
----------------------EQSLFELDWRPVRPSEPKTH-HGP----WGVLGAKPGAARLTEVGGAV----PAGD----TPRHLVLCLD-PD----L
LAEVGGTDARVLDWVQRFLAEERF---------------AESTL------------VVLTRLALD--TGGGERVESLPGASVWGLIRSAQTEHPGRFR-L
VDVDDAD----TSWA-RFP--DVLALDEAQLALRGGAYLVPRMTPTALANNRIEPEGDGFGGGSVLVTGGTGGVGSLVARHLVTEHGRSLVLASRRGMAA
--DGAAELVADLE----GAGAAVRVVACDVADRAAVADLLADLPR--AYPLTAVVHAAGVLADGTVESLTAESLDRVLGAKVGGAINLHELTREHTLTAF
ILFSALAGTLGTGGQANYAAANGFLDGLAARRR-ASGLVGTSLCWGWWEQSGMTEDLVDLSRIRRMGVAEMPTPEALALFDAAYTIDKPVLPARVDVSAL
RTADEV--------P-LILRDLVESG----------------RPL-KRAT---------T-TGDGGPLG---LPARLAG--------LAAGEAEVVLDWI
RDQVLGHVAVDADQAFTHLGFDSLTSVELCNRLASATALRLPSTLVFSYPTPRELGRHIFDL----------
>tr|S4AZ55|S4AZ55_9ACTN Putative Phenolphthiocerol synthesis polyketide synthase type I Pks15/1 OS=Streptomyces aurantiacus JA 4570 GN=STRAU_0346 PE=4 
----------------------TQPLYEVQWRPVKENKRETR-REP----WGVLGAKDGAGRLCEPADAV----LAGE----APRHLLLCLD-DG---DP
LAALAGTHTRVLGLIQRFLAEEAL---------------AGSTL------------AVLTRRAFD--TSGAESVESPAGASVWSLIRSAQTEHPGRFR-L
LDTDDAD----TSLA-RLP--DALALGEDQLALREGTFLAPRMAQAAPAN-QIEPEGDDFGGGTVLVTGGTGGVGALVARHLVTEHGRSLLLASRSGMAA
--DGARELVADLE----KEGALVRVAACDVADRDAVAKMLADMPP--ARPLTAVLHAAGALADGTVESLTAQSVEHVLRAKAGGALNLHELTREHNLSAF
VLFSALAGTLGTAGQANYAAANGFLDALATQRR-ASGLPGTSLCWGWWGQSGMTEDLVDLSRVRRMGVAPMPTPQALALFDSACALNKPVLPARLDLTAL
RSGDQL--------P-PLLRDLVETG----------------RPR-HRTN--------TT-PKDSGPLG---LPARLAT--------LSEDEQHAVLDWV
REQVLGHAVVDPDQAFTQIGFDSLTSVELCNRLASSTGLRLPSTLVFSYPTPRELGAHITGR----------
>tr|A0A0Q1CX37|A0A0Q1CX37_9ACTN Polyketide synthase (Fragment) OS=Frankia sp. ACN1ag GN=UK82_23620 PE=4 SV=1
--------------------RRSDSLYEVTWPPLRLAATDPPAATG----WAVVGADAGAVPAELGAGRTAAIEAGTA----VPDLVVLPLG-ASDIVDV
PAAARAATQRALELLQTYLSDRRL---------------DTTRL------------AVLTSGAVS--VAG--EDVDLTTAPLTGLLRTAQSEQPDRIL-L
IDLDGDP----DSRA-GLPAAAALASGENQLALRRGTAHTPRLVPAAAAAAAATPHWDLDPDGTVLITGGLGTLAHHLAHHLITHHHRHLHLTSRTGPDH
--PHAQTIRTELE----NLGATITITATDTTNPHQLQHLLDTLDP--HXPLTAVIHTAGTLDDTTLTNLTEDRLHTVLTPKIDGAWHLHXLTRHHPLKAF
VLYSSIAAITGNPGQANYATANTFLDALAHHRH-AHGLPATSLAWGLWNDSTXTENLADRARITQSGLRSLAPADGLALFDAAGTLHQPLLPAALDVATI
SATDGV--------P-PLLRGLVRPG----------------RRGAQGAA--------A---SRADAAA---LRGRLAA--------APDEQREILLEHV
RQEVLGHGTVEAERDFGELGLDSLTAVELRNRLNTATGLRLPATLTFDHPSAAALAAYLAEQ----------
>tr|K0F243|K0F243_9NOCA Beta-ketoacyl synthase OS=Nocardia brasiliensis ATCC 700358 GN=O3I_029065 PE=4 SV=1
--------------------AAADSLFRCEWHGIDLTAQASD-PVA----VAAVGTAQVGAR--------SDIESGAA----VPDLVVVDPTSIADTDDV
PAATATIAARALRLAQEWLSESRC---------------AGSRL------------MFCTRDAV---SARPADVLDPRVASVWGLVRSAQTEHPDRFL-L
ADIEPSV-----DAG-TLG--SALRAGIPQLAVRDGQVLVPRLRPMRAPDGGA---PWSELDGSVLITGGTGGLGALVAEHLVAEHGRRLILVGRRGVQA
--PGAPELVARLR----ESGAEVELAACDVADRAQLASLLARVRA--GHRLRAIVHAAGVLDDGVLEALTAERLDRVLRPKVAAAWHLHELTAELDLVAF
VLFSSAAGVLGAPGQANYAAANAFLDGLAGWRR-AHGLAAVSMAWGMWAQSAMTGELADRARLAGAGFLPLERRAGLRLFDATAVCAEPSVPLALDPVAL
RI--PL--------S-PVLADLVPAP----------------AA-------------------TAASGT---FGRQLAQ--------LRGSEREELLRLV
CVEVLRYDAVDPERAFTDLGFDSLGAVELRNRLSFETGLVIPTTVIFDHPSPAAIADYLHEA----------
>tr|Q0RTS6|Q0RTS6_FRAAA Putative Type I modular polyketide synthase OS=Frankia alni (strain ACN14a) GN=FRAAL0346 PE=4 SV=1
--------------------RRSDSLYEVTWPPLRLSAAGPG-ATN----WAVIG--SGAVPAELGASRTVAVEAGAA----VPDLVVLSLGPAPDLPDV
PAAARAATERAVDLLRAYLSEQRW---------------DATRL------------VVLTSGAVS--VAG--EDVDLTTAPLWGLVRTAQNEHPDRIL-L
IDLDADP----DSRT-ALPAATAQATGDNQLALRRGTAHTPRLVPATTPDAADAAGWNLDPDGTVLITGGLGTLAHHLAHHLITHHHRHLHLTSRTGPHH
--PHATALRTELE----NLGATITITATDTTNPTQLHHLLDTIPP--AHPLTAVIHTAGTLDDTTLTNLTPERLHTVLAPKIDGAWHLHHLTRHHPLKAF
VLYSSLAGLVGGAGQGSYTAANTFLDALAHHRR-AQGLPATSLAWGLWDDSTFTENLADRARIAQSGLRSLAPADGLALFDAAGTLRQPLLPAALDVATI
SAADGV--------P-PLLRGLVRPG----------------RRGAQAGT--------A---SRADAAA---LRGRLAA--------AADEQREILLEHV
RQEVLGHDTVEAERDFGELGLDSLTAVELRNRLNTATGLRLPATLTFDHPSATALAAYLAEQ----------
>tr|D3DDG1|D3DDG1_9ACTN Short-chain dehydrogenase/reductase SDR OS=Frankia sp. EUN1f GN=FrEUN1fDRAFT_7833 PE=4 SV=1
----------------------------------------------------------------------------------------------------
----GVVAADIRGVLSLASMDTTALG-----THPVLPTGLALTVALLQALGD--VGVTATSGAVSTGAGPSGQAQVLAQAQVWGLGRVAALEMPGRWGGL
VDL--PGALDPRVAEG-LAAVLTGTCEDQVALRPAGLFARRIVRARGGPGA-VADGSRWRPRGTVLITGGTGALGSEVARWCATEGAERLLLTSRRGMAA
PGAAELAA------ELTRLGAEVVVAACDVTDRDALAEIIAAVP--ADQPLTAVVHAAGTGDGAVLERTTPAELAAVVAAKTTGAAHLDDLLAGQLDAFV
-LFSSVAGIWGNPGQGAYAGANAWLDALAERRR-ARGLPATSVAWGPWAGAGMADDPRVRARTERHGLPPLVPEEALRALAQVGGGEPGVVVARVDWERF
VA---------------------------AFPRFVDEIPAARDAASRSRDGRSRSSAGLPSAGLPASPRSVGLRDRLASVPA--SGRH-RL-LLGLVRSE
VAAVLSPEDIPADRAFTDLGFDSLTSVETRNRLAQATGEQLPAVVVFDHPTPDALARHLLTL----------
>tr|C9YYI1|C9YYI1_STRSW Putative type I polyketide synthase OS=Streptomyces scabiei (strain 87.22) GN=SCAB_83901 PE=4 SV=1
----------------RGRTTIDGWRYQVTFKPLHLTPGTPALTGTWWVVVPAGAAGHPLRALERHGATAV---------PVEIGTTGTDRAG------L
AARLGAATAPDGGVLSLLALAEQPYADGT-----ALPTGLALTTTLLQALGD--AGINCGAVSVGRSD----ALTAPAQATLWGLGAVAGVEYPERWAGM
LDLPSD----LDEAGVRLAAVLAGLDGEDQIAIRSGVYGRRLVRARPAEETT---ADAFDPDGTVLITGGTGALGAHVARRLARSGARHLLLTGRRGPDT
PGAA------ELVAELAGLGAETTVAACDAADRDALATLLADIPEDR--PLRTVVHAAGLLDDGVLDTLTPERAAGVLRPKMDAALNLDALTRDLDTA-F
VLFSSLAGTLGGTGQGSYAAANAFLDALAEQRR-SLGLPATSVAWGLWAGDSAA-DSA-RERLVRNGLPPMDPELAVTALEQAMGRA-------------
-------------EPRLVLCDFAWDR--------FAPAYTALRPSA---------ALRDLPDVRDQETEADSLAARLA-------ALSPQERQEELTRLV
ATEVAAVAGIDPDRVFKDLGFDSLTAVDLRNRLSEATGLRLSVTLVFDHPTVTALVDHVRSE----------
>tr|A0A066Z6A5|A0A066Z6A5_9ACTN Polyketide synthase OS=Kitasatospora cheerisanensis KCTC 2395 GN=KCH_04110 PE=4 SV=1
----------------ADDRTADNWRYRVAWKPLPAA-ERPRLTGSWLLVAPAGAAEDPADALSGHGATPV---------LVEAGHDATDRAR------F
AALLRRADGPPAGILSLLALAEEPHGEGS-----ELPLGLTLTVALLQALGD--LGTDRGAVSVGRSD----RIDSTLQALTWGLGGVAGVEYPQRWAGL
VDLPRR----LDDAATRLAEALANPDGEDQLAVRTGLYGRRVVHAALGDTAP---ARDWTPEGTVLITGGTGGLGAQIARRLARTGTAHLLLTSRRGAQA
PGAE------ALLAELRELGAEATVAACDVADRDALAELLAAIPAER--PLRAVLHTAGVLDDGVIDSLTPERAAGVLRPKLDGARNLDALTRGLDTA-F
VLFSSLAGTLGGTGQGSYAAANAHLDALARHRR-DLGLPGTSVAWGLWGGETLAAGAV-AERLIRDGLPAMDPATATTALLRALDHE-------------
-------------DTNVLVADFAWDR--------FTRAYTALRPSA---------ALADLPEVRDGADGAEPPALRIA-------ALPPAERDRALLDLV
RREVAAVEAVGPDQAFKEIGFDSLTAVELRNRLAAATGLRLSVTLAFDYPTATALAGHLRAE----------
>tr|G2PEV3|G2PEV3_STRVO Beta-ketoacyl synthase OS=Streptomyces violaceusniger Tu 4113 GN=Strvi_4158 PE=4 SV=1
----------------RDQSTIDGWRYKVSWKPASDL-AEGSLSGTWLVVVPASRAGDEVAGFERHGAGVV---------SLVVDERDLDADV------L
AERLRAEVPELGGVLSLLALDEEPCPGYP-----ALSGGYALTLVLVRAVVW--AGIERGAVSVGRSD----RLTSPTQAMVWALGRAAALELPPLWGGV
VDLPES----LDEAVARLAGVLSAGGGEDQVAVRSGVFARRLVRSAAA-VGE---GISWRARGTVLVTGGTGGLGGQVARWLVRSGAEHLVLTSRRGLEA
EGAA------ELKAELEGMGAEVTVAACDAADRDTLAAVLDAVPEHR--PLTGVVHAAGVTMTASLLETELADAARAVSGKVAGAVNLDELLGDREDA-F
VVFSSISAVWSGAEQGVYGSGNAFLDALVERRR-ARGLAGTSVAWGPWAEEGMVTGDA-GEQLARRGLPAMAPELAIAALERAVAGD-------------
-------------DGLVTVVDVDWER--------FAPAFTAVRHSR---------FLSELEEVQRAEAAGAQLRERLK-------PLTEGERDRALLDLV
RKHAAAVEMVEPNRAFRDLGFDSLTAVDLRNRLAAETGLGLPTTLVFDYPSAGTLAAYLRTE----------
>tr|A0A017TA30|A0A017TA30_9DELT Malonyl CoA-acyl carrier protein transacylase OS=Chondromyces apiculatus DSM 436 GN=CAP_3204 PE=4 SV=1
----------------AARGTPADWLYAVEWQERPRGTPPPAPAAPWVILADRTGLAEA---IAARGEACVRISPGSGYLRLSDTHREVDPLS------S
EQ-LGGVAGRSRGILHLWSLDAPS-TEAL-----ALDALEGSTVSVLRMLAAP-AEAAREAQALTECPA---APPALAQAPLWGLGQVLSLEHPDLWGGM
IDLDGT----SASAASALLDEICQPDPDDLVALRATRHVPRLVRKPEV-SAT---PITFHSDAAYLITGGLGGIGLALAHWLVQRGARHLVLLGRRGLPE
RPARESLQKAAAIALIASLGAVVEVVSADVGDRPRMQEVIATFGRDRP-PLRGVFHAAGLSTPELLKDARPETLQAMLRPKVNGTWILHELTRDLPDV-F
VSFSSVSSVWGSLGLGLYAAANHFLDVFASYRR-AAGLPALTVNWGSWSGVGMVSDDM-ALFMAKMGIDSMPPGPSLDVLGQLMASG-------------
-------------ATRCTVATVDWRK--------FKPLYEARRVRP---------LVSTLDV-RLGGPAASQLSERLG-------KALPGERRDLVVEHV
EGLVARVEVRGLRAGFTAMGMDSLMAVELKTKLEDSVGQRLPSTLAFEHPTIEALTEYLLRE----------
>tr|D7C2J3|D7C2J3_STRBB Type I polyketide synthase OS=Streptomyces bingchenggensis (strain BCW-1) GN=milA2 PE=4 SV=1
----------------HDQARIDAWRYDEVWQPLDLADAEPMPPGDWLVVIPARQAGHPLSGLREHGGIRTT--------ELVLDTADIDPLV------L
RQHLAPDDVSICGVLSLLAFDEEPHPEHP-----HLPTGTALTLTLIQTLTTH-PNTTQTATTTHPTD----TLNHPTQAHIWGLGRTTALEHPNHWGGL
IDLPTT----PTPHLHHLTTALTTQHNDDQLAIRTGLQTRRLTRTATT-PSN---PQPWKPHGTILITGGTGAIGTHIATWIATHPHCHLLLTNRQGPNT
PHNT------QLHHHLTQLGATTTITTCDTTNPNQLTNLLNTIPPTH--PLTTIIHTAGINLKSTIADLSAADLAETAGAKATGAAILHELLREHTER-F
VLFSSIAGTWGSANQAGYAAANAYLDALAQHRR-AQGLPAISIAWGPWDGAGMAAGDT-RAHLRRRGLRAMSPDLALAALDRILGHGP------------
------------DSAAAVVADVDWED--------FATTFTARRPAP---------LIDDIPEVRQ-PPSADSLREQLA-------QRSPKEQQQALLDVV
RTHAAAVESIDAQQAFSALGFDSLTAVEFRNRVAAATGLALPTTLVFDHPSPTECATHLRTA----------
>tr|A0A0N1GBL0|A0A0N1GBL0_9ACTN FkbH like protein OS=Actinobacteria bacterium OK006 GN=OK006_9711 PE=4 SV=1
--------------------PLDGALFETRWQPCPAA-QQPPAEGSWLILADDTGVAAELAERLGSTVPRVIARRGESFGVEGPGRYLLDPADPRHLARL
LDEAFP-DGPPERVVQLSALDAPA-ITDAGTAEEAARLCCLSTLHLVRALADRPGRAPRLFVPARGSQAAGDSTTHPQQALAWGFGLAVAQEYPELSATL
IDLPPT------DGVDALWTQLRHADDERLVALRESGRLVPRLARTRPDDGG---NGEVTSDGVYLITGGLGGLGRVVAERLVRRGARRLALMSRGEPDG
HTA---SWISG----LEEHGTTVHLARADVADREELTAALDRREA---GPIAGVVHAAGVLDDATVANLTDERVLRVLAPKVLGTTLLTELIPEAESL--
VLFASAAGLLGSAGQSPYAAANAFLDAWAHHLS-RVDRRALSLDWGAWAGVGMVAESGIRAAEGRSGLLALSPQDGGELFERVLATSRRLAPLALDWE--
---TLAHDPD-AARTRPILGDLITDGADDLVASVFAATTA--R-----DRADRL---------------EAYVRARVQVSEGTV----------------
--------DVSATTALKELGLDSLMLVRLRNAFARELGAELPAATVFSASDIRGLARALGE-----------
>tr|A0A0M2JL38|A0A0M2JL38_9ACTN Polyketide synthase OS=Streptomyces mangrovisoli GN=WN71_15135 PE=4 SV=1
--------------------PLDGALFETRWQPRPAPASKDAEDGGWLLLADGTGVADELAARLGESAPHVVARRGDSYATEGPGRYVLDPTDPAQLRRL
LDEAFP-DAPPARVVQLSALDAPP-VDGTATADLAARLCCLSTLHLVRELTDRPGRSPRLFVVTRGSQAAGDSGTGPQQALAWGFGLTVAQEHPELAATL
IDLPPT------GGTDALWTALRDADDERLVALRGAERLVPRLARTRPDDDG---AAARTTDGVHLITGGLGGLGRVVAERLVRRGARILALLSRGTPDA
DAA---GWIEG----LRERGVTVLHARADVADRAALTAALARHEA---GRITTVVHTAGVLDDATLANLTEERVLRVLAPKVLGTALLTELVPEADDL--
ILFASVAGLVGSAGQAPYAAANAFLDAWSHHLG-RTGRRSLSLDWGAWTGVGMVAGSGVRAEQGRSGLVPFTPEEGGELFDRVLTSGRRLAPVALDWE--
---LLALDPD-TIRTRPVLADLVTGATDDLVRRVFAATTQ--D-----ERTTWL---------------ETYVRARVEVSGGTV----------------
--------DASATTALKELGLDSLMLVRLRNAFARDLGAELPAADVFSANDIRGLARALAT-----------
>tr|A0A0H4WVP1|A0A0H4WVP1_9DELT Malonyl CoA-acyl carrier protein transacylase OS=Myxococcus sp. (contaminant ex DSM 436) GN=A176_002590 PE=4 SV=1
--------------------SLDEWLYARQWDALALEGHQGSASGPCLVLSDRAGVGDALARTLAREGPCVVAFQGTGLRQVDARTFEV-PTEPE---AL
AEALRSLPVDLSDVILLWGVDSPVETLDAEGLGQAARVGGGAALGLLQFLLNYAGAVWL--VSRGAQPVTPGATPGLAQSLLWGMARPLAIEASELDCRC
VDLDPQ----GAAQAELLARELRARTADNQVAFRDGR-YVARVESRKVAAAPSVRSDALRADRTYLVAGGLGRLGLLTAELLASRGARSLVLTGRGPGS-
--AHAADRIERL----RQQGVRVDYHQVDIADTESVAALLREVA-RDMAPLGGVFHSAGVLDDGVLRQQRWERFDTVLRPKMRGAWNLHRLTADLPLDHF
VMFSSVASLVGSAGQSNHCAANAFEDALAHHRR-ARGLPGLSINWGIWAG---DAGAQVSEEARTPGFGVLPKEQGLRALELLLAS--SLPQVGVA----
------------------AIDWA------VFGAGRPSPYAELRSKVASTKP----------------AERAAFLETLRS--------APIPRRRQLVMDY
VRDQVSSASIDPARGFHELGIDSLAALQLKNRL---------------------------------------
>tr|Q091C3|Q091C3_STIAD Oxidoreductase, short chain dehydrogenase/reductase family OS=Stigmatella aurantiaca (strain DW4/3-1) GN=STIAU_0878 PE=4 SV=1
--------------------SLDELLYERRWEPLALEGAGEGDNRPCLILADRAGFGRQLAEELTRGGTCFLAFRGQAFRRLDETSVEV-PGEPA---AL
AEALRTLPASVSDAILLWGLDGPAEGMDVESLGQATLLGGGGALGLLQYLMGYSDAVWL--ITRGAQPVKPGQPPGMAQSVIWGMARPVAIESSELDCRC
VDLDPR----GEAQVGLLAQEIRRRSADNQVAYRQGR-YVARVEARKLATPLVERVQRFRPDRSYLVAGGLGRLGLLTAELLANRGARNIVLTGRDSVS-
--PQAAERLERL----REQGVRVEYRQADIADLGQLSALLREVG-REMAPLGGVFHSAGVLDDGVLRQQSWSRFETVLRPKARGSWNLHVLTADMPLEHF
VLFSSVASLVGSAGQANHCAATAFQDALAHHRR-ALGLPGLSINWGVWAG---DAGARVNEQARTPGFGVIAKQQGLQALEMLLAA--QVAQAGVA----
------------------VIDWA------AFGAGRPSPYADLREKAGG-RT----------------AGRETFLAKLTS--------APIAHRRKMLMDY
LREQVSRESIDPAQGFSEMGIDSLAALQLKNRL---------------------------------------
>tr|L7UIA0|L7UIA0_MYXSD Non-ribosomal peptide synthetase OS=Myxococcus stipitatus (strain DSM 14675 / JCM 12634 / Mx s8) GN=MYSTI_06014 PE=4 SV=1
--------------------TLDGQLYVRRWEPLALDVPARAVSGPCLILADDAGLGHKLARALERDGTCLLAFRGQTLRTLDDKSFEL-PEDPE---AL
ADALRTLPASLSDVILLWGLDGASEDLEGERLDADARRGCGSGLGLLRYLIDYSEAVWL--ITRGAQAVASGQPSGLAQSLLWGMARPLAIESSELDVRC
VDLDPR----GEAQVEALAREVRGRAADNQVAFREGR-FVARAESREVVAESSRD-GPVRSDRTYLVVGGLGRLGLLTAELLAHRGARSLVLTGRGSVG-
--AEAEGRLERL----RARGVRVEYRQVDLADEGELSGLLQFIA-DDLAPLAGVFHSAGVLEDGVLRQQTWARFERVLRPKVRGAWNLHRLTSGLALEHF
VLFSSVASLVGSAGQSNHCAATAFEDALAHHRR-ALGLPGLSINWGVWAG---EAGARVDEQSHTPGWGLLSVPQGLRALEALLTS--PVAQVGVA----
------------------EIDWA------VFGGGRTAPYAELREAARG-QP----------------EGRARFLETLSE--------SPVPARRKLLMNY
LREQVSGASIDPAQGFNEMGIDSLAALQLKNRL---------------------------------------
>tr|A0A0F7BML9|A0A0F7BML9_MYXFU Peptide synthetase OS=Myxococcus fulvus 124B02 GN=MFUL124B02_24085 PE=4 SV=1
--------------------PVDGWLYERRWEPLALEAAGTKERGPCLILADERGLGPLLARALERDGTCFLAFRGRTFRALDDTRFEL-PEDPE---AL
AEALKTLPASLSDVILLWGLDGAAEDLDLARLDADTVRGCGSGLGLLRYLIEYSQAVWL--VTRGAQAVATGQPPGIAQSLLWGLARPVAIESSELDVRC
VDLDPR----SGAQVELLTRELHARAADNQVAFRGDR-RVARVSAREVLTASSRWADAVREDRTYLVVGGLGRLGLLTAELLANRGARSLVLTGRGVVG-
--PEAAERLERL----RTLGARVEYRQVDVADEDALAALLREIS-GELAPLGGVFHSAGVLDDGVLRQQRWARFESVLRPKVRGAWNLHRLTSKLALDHF
VLFSSVASLVGSAGQSNHCAATAFEDALAHHRR-ALGLPGLSINWGVWAG---DAGARVDARSHTPGWGNLPVREGLAALEALLTS--PVAQVGVA----
------------------EIDWA------VFGGGRSSPYAELRDAARG-RT----------------VERARFLEKLSR--------SPVMHRRKLLLEY
LREQVSGASVDPSQGFSEMGIDSLAALQLKNRL---------------------------------------
>tr|A8LW93|A8LW93_SALAI Beta-ketoacyl synthase OS=Salinispora arenicola (strain CNS-205) GN=Sare_4951 PE=4 SV=1
---------------------------------------------------------------------------------------VILIGDPEVTAPL
SAQFTAAGTDSLEVASGWIVDLPPAALADEPLERATRRAAWTLIRTVQQLIEVQAPQVLTKG-VRAAVDE----ASLAHAPLWGIGRIVAGEHPEVWGGL
IDTDGIEPGNGEQLLRVLRT-AAGT--EDVISLTSGDLTAIRLAPIERSADG--TPLQCSPSGTVLITGGLGALGLEVARWLVDRGARRLLLAGRRGPPR
VSDRQIDAVLALEA----LGVTVGVVALDITDADRVAATLAP-GALGLPPIRGIVHTAGVVKDDLVDKVDLDGLREVLAPKAGGALVLHRLFPPGSLDFF
VMFSSCGQFARLSGQTSYAAANSVLDALAAHRN-ASGHTTISLGWTAWRGLGLSENIATMFEANSRGLEAVSAAEAFRAWAFGDRFQASYQAI-------
-----LRVLP-TP---------PNLPRVPMLRELTATNEAGTD--H-AGQ--------SFTLDLGSLTQDEAIE-----------------RVTTDVREQ
VATELEPASIELKRPLVELGVDSVMAVALRVRLQRRYGLDLPPTILWAKPTVAALSEHVHTN----------
>tr|Q84HC6|Q84HC6_STRCZ Iterative type I polyketide synthase OS=Streptomyces carzinostaticus subsp. neocarzinostaticus PE=4 SV=1
---------------------------------------------------------------------------------------VILVGDPEATVPL
AEQLESAGMTCVQVGDS-ETGLRPDLFSDTAPEEEAERVSWLLVRTVQRVAEIRPAQCVTSD-VRRARDE----RSVAHGPLWGLARIVAGDHPELWGGA
VDIGPSADGIGARLVALLDG-AAGT--EDVISLTGEGAEVARLSRIDRSADG--TPLQCSPSGTVLITGGLGALGLEVARWLVDRGARRLVLVSRRAPNR
VTDRRIDGVLALEA----LGVTVRVLALDITDVDQVSAALAP-EALGLPPVRGVVHAAGVVNNALVDKVDLEGLREVLAPKVRGAMVLHRLFPPGDLDFF
VLFSSCGQFARLSGQASYAAANSFLDTLASHRN-AGEHTTVSLGWTAWRGLGMSSNIDTMFEANSRGLEAVSATEAFGAWSFGDRFQSDYQAI-------
-----LRVVP-TP---------VHTPRLPVFRDLPVSGETDGP--T-GDQ--------LFTTTLEGLPEQEARE-----------------RITADVREQ
VAGVLDPSEVEVKRPLVELGVDSVMTVALRVRLQRRYGLELPPTILWAKPTVAALSEHVCDS----------
>tr|A9AVG0|A9AVG0_HERA2 Amino acid adenylation domain OS=Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785) GN=Haur_2008 PE=4 SV=1
----------------------PALLQQVVWTQTALAAPSDQALEQWVVIADNNPLADQLLRLLNTANRACVVTTSA-----------------MLNSVL
PTISNRYGLSSDEVIAQTNAFEQ-----------TCYVGALQLLDSIKSILAQPNGLWVVTAGAYAINNHTQVV--APQALLAGLAAALPD--QRIKFPC
VDLELTDD--IPAQGQLLLGELQTQPSNGVVAWRAGKRLTRTLAPLAGGP---SKRPPSEKPGVIIIAGGTGGVGAQLARHLATHNQPTLILLGRSALDA
QRS------SLL-EQLNDLGAVARYCQVDICDPQQVDQLIAELAASSN-GIFGIIQAAGIVDVGSLQAKSAQQLLAVLAPKVSGTWLLARALERYQPAFF
INCSSIAAVVAGLGIADYVAANAFLDAFAASER-QAGRPMTTLNWAAWDGIGLAANPMLVEQLRQRGLPPLHPSQALQAFDQVLYTEQRQVVI-------
------LAPVESAEPQ------------------YQATKAAITPPVAIS--------------NPAM----NVTQQIQALVGNALK--------------
----LPPEQISEDASFLALGLDSLQAVDLVKQLEQTLGTTLPLTLFFEFQTIRELVAYLS------------
>tr|A0A0P6YY26|A0A0P6YY26_9CHLR Uncharacterized protein OS=Herpetosiphon geysericola GN=SE18_08255 PE=4 SV=1
----------------------PALLQQLVWQPTVLPASAEQLIEHWILIASPDELAKQLAAMLNTTNQPCVLTNGE-----------------SLPKQL
ATLGQRYGLPTT--------SDQ-----------PATAGVLDLLAVSKLILALPEGLWVVTAGAYPIEQQEQIA--PEQALIAGLAAALPD--QHLGIPC
VELALNAE--AAAQLQALALELQFQPSNGVVAWRGGQRLARALATLPAIT---TSHKPAELPGVIVIVGGAGGVGAQLARHLASNNQPTLILLGRSALDQ
ARK------TLL-AELTALGATAHYRQVDICLAHEVEQLIAELAATEA-GIFGVIQAAGIADVASLHSKSAEQFAAVLEPKVKGTWLLARALERHQPAFF
LNCSSIASVMPGLGIPDYVAANAFLDAFAASER-QAGRAMTALNWGAWDGIGLAATPMLVEQLRQRGLPPLQPSQALHAFEQVLYADQRQIVI-------
------VAPAETQQPQ------------------AISQPL-LKRASAAS--------------LNSN----ELSQHIQALVAKALK--------------
----LPAEQIATDASFLALGLDSLQAVDLVKQLEQATGTILPLTLFFEFQTISQLAAHLS------------
>tr|E3FE06|E3FE06_STIAD StiE protein OS=Stigmatella aurantiaca (strain DW4/3-1) GN=STAUR_4831 PE=4 SV=1
--------------------ELPNWLYSPQWRPVPPHPETPVRQVHCLVFADKGGLSEDLSRHVRGAGKCTLVHRGDEFRRNEDGSYSVPLRNPEAFLRV
VDEVSREGLVPSHVVYLWGLDVPKPDLSVA---QLQDEACGGVLYLTQALLKGSAGTAVSSLWVITRGAQRVAFPGLLSSPLWGLGKAIAYEHPELDCRR
VDLTPRR---GEDEAGQLWTEFLAHDREDQVTFRNGTRHVLRLGRWDWEQAG---RLQFKADATYLVTGGLGGLGLLVARWMVERGARNLVLLGRKRASD
VSTDE---VREMRG----RGATIVLAGVD-SDLDYVMAGISK----RMPPLRGIIHAATEVDDGILVHQTRERFGRVFTAKVSGAWNLHRWLADKELDFF
LSLSSSTSLMGASGQSNHLAATAFLDGLAEYRR-SLGLHGQSSSWGAWAQPGDEAAQALDSRMRKRGVGMMHSQQAFA-VLEQVFGQVPAV-AGV----M
PIHWPTFLGLPGDDLPPLFADFWSDAGP---GRAGSEIRHELVRRVRGSS----------REEARSAVL-TYFRERILEMGTAQLPEP------------
------------EQTLHELGLDSLMGVELKKLLLTELRVEFPLQALLAGKSIVELADSL-------------
>tr|L7UHB2|L7UHB2_MYXSD Polyketide synthase OS=Myxococcus stipitatus (strain DSM 14675 / JCM 12634 / Mx s8) GN=MYSTI_06007 PE=4 SV=1
--------------------DLPAWLYAPRWRRVAL---SERDTAHCLVFSDRGGLGAALARSMSGTARCTFVHRGEVFRRHDDGSYEVPIRNPEDFLRL
TEALASEGTVPSRVVYLWSLDGPKPELTVS---QLQDEVCGGLLYLTQALLKAGASHPASSLWLVTRGAQRAGVPGLAGASLWGLGKAIAYEHPELDCRR
VDVDPGR---DVESARALWTELRSRDGEDQVLLHEGARRVLRLARWDWEGAG---RLQFRADATYLVTGGLGGLGLQVARWMVRRGARNLVLLGRKRASD
VSTEE---VREMRA----QGAAIILAGVD-SDLDFVMAGISK----RMPPLRGIVHAMTEVDDGILLHQTRERLGRVFTAKVAGAWNLHRWLEGTPLDFF
HMVSSSTSLMGGSGQASHLSATSFLDGLAEYRR-SLGLPGQSSSWGAWAQPGDEASEALDARMRKRGVGMVPAAEAFS-VLEQVFGPVPAS-VGV----M
PIHWPTFLGLPGDGPPPLFADFGGDARP-----ARAELRRELLRRVRGGS----------VEEGRGAVL-EWFREQVLELNASQWPEP------------
------------EQTLHELGLDSLMGVELKKLLHAQLRVEFPLQELLGGKSIGELSGSL-------------
>tr|A0A0F7E6Z7|A0A0F7E6Z7_MYXFU Uncharacterized protein OS=Myxococcus fulvus 124B02 GN=MFUL124B02_24050 PE=4 SV=1
--------------------ELPTWVYAPAWRPVPP---TTTPPGHCLVFVDQGGLGEALSRRVGEAGRCTFVHRGEVFRQREDGGYEVPTRNPESFLRL
MEALSAAGHVPSHVVYLWSLDVPEPELTVA---RLQDEACGGLLYLAQALLTAGASHPASSLWMATRGAQRAGLPGLLAAPLWGLGKAIAYEHPELDCRR
VDLDPRR---DPDGAQALWMELSSRDDEDQVLLREGRRHVLRLARWDWEGEG---RLQFKADATYLVTGGLGGLGLQVARWMVERGARNLVLLGRKRASD
VSAEE---VKEMRA----RGAAIILAGVD-SDLDFVMAGISK----RMPPLRGIIHAATEVDDGILVHQTRERLGRVFAAKVSGAWNLHRWLSGTPLDFF
FSLSSSTSLMGASGQGNHLAATAFLDGLAEYRR-SQGLPGQSSSWGAWTQPGDEAQAALDARMRKRGVGLVPTRQAFA-ILEQVFGPMPAV-VGV----M
PIHWPTFLGLPGDGPPPLFADFGAEAGA---GRAGAELRRELLRRVRQGS----------AEDGRSAVL-EWFRARVLELGVTQLPEP------------
------------EQSLHELGLDSLMGVELKKLLHAELRVEFPLQELLGGKSIGELSGSL-------------
>tr|D3HR03|D3HR03_LEGLN Putative non-ribosomal peptide synthetase/polyketide synthetase OS=Legionella longbeachae serogroup 1 (strain NSW150) GN=LLO_0975 PE=4 SV=1
--------------------SLPNYSFARFWHPASAHQPKKQA--QLYAPA-----WQQVREFSSHEIRTITIYAGPKYNKLSPTHYVLNPAQNNDYETL
WRDIKNYGV-IQRIVYAWSYSRNCEKNAAEWEYDCL-LSPMSLLQ--TLIHHYTNPIILLVCSYSAKVVPTD----SIKA-DAGLLEGVPQEIPSISIQA
LDLPANMT---------LMDQLLVDLQGQKLALRFGCFWWQAYNPVS-EKTG-----IA-PQSTVVISGGSGGIAQALATHIVTNYQCKVVCLSRTKKL-
---PQQSTI--------------QMMHCDVTDLEQVQQTFA----CIAGPIEAIIHLAGQAAEKLFIRKDHHLVKKALTPKTQGTRHLAA-MSQHYNIKL
ILFSSASSLLGGIGELEYCAANHYMDCFALENN-TASQQVLSINWGAWAKLGMRQNLLTNHP-----------QEEL-TICEALN-----LFDQAVKSTL
PQLAAIPY--P-L------TELK---------IRY-------QNHLQQALTVKKAPPSP------------AFQTP--RPILSSSYRPPKQDLEKQLSLI
WQRHLGIEQIGLDDNFFELGGDSLTALEMKSETEKILGIELTLDVFMRSQTIDALLK---------------
>tr|F1TIW2|F1TIW2_9FIRM Beta-ketoacyl synthase (Fragment) OS=[Clostridium] papyrosolvens DSM 2782 GN=Cpap_0012 PE=4 SV=1
-----------------------------------------KLQGSYIIFDGTDGLSQHISRQLSSEDNSITVYLGKKYYIAN-NYIEIDASTKEHYTHL
FDYLKTKNINISGIIYIPGSTVKNDNLSINNVEKDFYDNLSSLFNIIKSLIKNKQFITLTFNGDNTYNEKLNIYPHMQSLQV--LTKVFSNEEKGVSFLN
LDYEASADL--EFIGGTVADELLTADRNMDVCYRKGKRFVKDFVKINVEPSN---SNCIKSMGTYIITGGGSNIGVKIAEFVVKQAPVRIAFIGRSQEPS
EK--------LKEAIAEKAGSKTMYFSCDVADLTELEKTVKKIEDNFG-EVNGIFHCAGIKDDSLLQNKELPAFKKVLSPKVKGLLNFERIFSNKPVEFV
LLLSSVSSYFCNQGQADYSVANCFYNSYAKSAFKKSAKRVISLCLPFVNGGGMKSTDIVLKRMENYGIYSVELEEVIEALKVSLSHKDINTFCKHTGSAL
----------------------K------IIPGVYSNKIKCYN-K-NGKSRV---------------PCNNIDKNRCDNLLHNAENE---DNVKKYIRTL
ILRLLDPQEMDDSVNFGDYGMDSMLIKEATVLFEREFNTQIESSIFLEYPNVAELAGYLSE-----------
>tr|F1TBP3|F1TBP3_9FIRM 6-deoxyerythronolide-B synthase OS=[Clostridium] papyrosolvens DSM 2782 GN=Cpap_2600 PE=4 SV=1
-----------------------------------------ENSFVWVVFCDKQELYANIRESLKTRNKVILVFADDKYYKKD-SCNTINSYLEEDYKVL
FKDIIKDFGRVDTVINLWAY-------TNTEFQETTYASVYGLLGIALGLNANKGLISITNHSEDIDKISVGGYP----VHM--LSRLISAEIKNIAARS
IDFNGLESK--EVVEDVIFKYSLTKNGFSELAYRHGKAYIRMLKKNTLQKIL---NSVWKDGGVYVITGGATGIGAEIGLHIAKKVKAAVILIGRTKLPE
KSEFREAVIEKIENIIQEAGAKVEYYNGDISDELKTIEILDNISKRFG-HITGILHCAGAKRDGIITAKSFKDFQYAIAAKVSGISNIKKAIEGKSVDFV
VAFSSIAALYGTPGQSDYSSANALMDAFINDWSGNTETFVTSINWTLWDGAGMDIPLLAKRKMENDGLLPLEISDGITALERLLQDRKASNYIKLSESD-
----------------------K------FIKDLFESKMRNPMSK-NGLFLSGT------------QSSKNMSVHKTTN-----TFE---KETKEFLLKM
LSELLEATDIDTSRGLDEYGMDSLAIKEALAALEKQYDTVLEPSLFEENPTIDKLVVYLAD-----------
>tr|F4Y423|F4Y423_9CYAN CurM OS=Moorea producens 3L GN=LYNGBM3L_74580 PE=1 SV=1
-----------------ARLTTKKWFYKVQWISQAIKPQRNNQVCHWLILTDSKGLGKSLATHLGNECSVVYYEPG---------IYHINPSHPQEFEQV
YQTIFENGKLPQKVIHLWSLDTASQDLTTETLEQAQLWGCGSTLHLLQTLVKNPTPPKLWMITRGTQPVLSPTELTVATSPLWGLGRTIASEHPQLWGGL
VDLDPQ---GSEDEVEVLLQQIIDKEDHLAV--RNRKIYVRLL--KHIPQES---QPLSRSDATYLITGGLGALGLKTAAWMAEKGARNLVLISRRQPS-
--EQAQQTIQSLEEL----GTQVKVLSADISVESDVANILEQIQ-TSLPPLLGVIHAAGVLDDGLLQQTNWERFTKVMAPKVNGTWNLHKLTQHLSLDFF
VCFSSMSSLLGSPGQGNYAAANAFMDAVVHYRR-EMGLPGLSINWGGWSEGGMATRLAHQNRMQTAGISLISPEQGIQVLEELVRTQSTA-QVGV-----
-----------------LPVDWS------VLAKQFSS-----------ANPSSLLLELLQQETSSEKTDERI----LEKL-----QAAPITERQDILKNY
IQKTINPSKISTDDNFVELGMDSLMGMEVVNKLSGDLDFIIYPREFYERPTIDSLTQYLSAE----------
>tr|G2NTV8|G2NTV8_STRVO Beta-ketoacyl synthase OS=Streptomyces violaceusniger Tu 4113 GN=Strvi_3959 PE=4 SV=1
--------------------------------------------------------------------------VSADSAPPTASWALVGPRHWPAYPDL
-AALRAALDGAPDVVVLSGAPDATPPDE--TPT-RVRAVVHDVLGTTWLTDERFSGARLVIATRGAVAGAGDAPADLATAPVWGLVRAAQAEHPERILL-
LDLDDD--TA-SRDVLRTALPAAVAGAESEVAVRAGTAHVPRLVKVRPDEDQDTPPRALDPDGTALITGGTGALGRLVARHLTAHGVRHLLLVSRRGGIT
GD------IDAFADELTALGADVRIAACDAADPEALAALLATLPAAH--PLTAVIHAAGVLDDGVVTAMTPEQLDTVLAPKLDAAWHLHRLTRNMDAA-F
VMFSSAASIMGNGGQANYAAANMFLNALAEHRR-AEGRTAHTLAWGLLASAGGMTGHLELARMARSGIAPVSGEQALTLLDTALTTDHPTL---------
---------------VPARFDLA------ALRTRAAA---GPLPPV----------LRRLVHVPTRAARTSSLSGRLAGLPT----EEQDRLIGELVRDQ
VATVLAHPAIELGRAFQDLGFDSLTALDLRNRLNAATGTRIPATVIFDYPTPDALVRFLRER----------
>tr|F8TTM8|F8TTM8_9BACT Polyketide synthase OS=uncultured Acidobacteria bacterium C5 PE=4 SV=1
--------------------------------------------------------------------------YGMTATDVRPHHPLMAPRRWEPAGQA
-LILANATVSLACTLVSGERTFQIDPDR--SDS-RTHRLCESTLYLALTSASLAEPPRLAIVSRGAVS--GETLPGLAGSPLWGMGKSIALEHPELHCLC
IDLPAD--GGLDE--ARSLRDEIRRSTDDQVAYRGDKRCAARIIRDAGP--APEAEFECRPDATYLITGGLGDLGLHAAEWLIVHGARHVMLVSRHGARP
EV------EGRIS-KLGSGGAQVSVRQADVSDKQQVAALFGEIAASWP-PLRGIVHAAGVFDDGTLLELTAERFAAVLAPKIAGAWYLHEQSRELPDV-F
VLYSSAASLFGSAGQASYVSANAFLDALAAART-AEHLPAVSINWGGWSAIGFAARSGT-RVLRGKGIGSLTPAQGAAALDRALTSGHGQL---------
---------------GIVAVDWQ------KFFEARVS---A--SPM----------FAAFA-------TRPRLLDALQGKSL----AEVHAWLLQYVASQ
VAAVLGLASVSTTRNFFQMGMDSLTSVELRNRLRDGLGQSLPATVAFDHPSVPEMADFLAKP----------
>tr|A0A0N8R8Q8|A0A0N8R8Q8_PSESX Non-ribosomal peptide synthetase/polyketide synthetase OS=Pseudomonas syringae pv. cunninghamiae GN=ALO74_04314 PE=4 SV=1
------------------------------------------------------------------YRHVIEVQAGNGYQQLGPNLYELDPLDPLAFSRL
IAELDQSGQVATELDWLHALSVGG-VVNEQSLAAAQWACLDTVSAFLQAWGQQKTALRLWLLSWQACPVNGQVM-RPELAALAGITEVAPQEY-PIRCHW
LDLPTAQCGSQALQLASLLAE--PTSLPRRMAIRDGYLWQPQLQPGPLALPK-VASNLLPVNGTFLVLGGTGGIGRTLCEHLLRSSQRRVVLLSRRGPQE
LGD-----------YAAR----IDSVQADIADLARWPKVLEQ-LRERYGHFDGVIHAAGTGAGSLIRQRDAHLLSEAMASKTRGMLAV-EALIEQMPGFV
LYCSSMSALFGGAGHLDYAAASAVLDGFAHYRPNENGCVRLGINWDIWRETGMAAASGIGDEAHQRHLAGMSAQEGCQVFDAAMTAQLPQLLTYLNTA--
--------------------------------RQFY------PARHSGAGLTLV-----------------------DT---APAVAAETGLPERLHGCL
C-KWLGVSALDPDDSLYELGADSLTLLDLIDELQAATGVVFQLSQFSHKVSLREVLALVQSA----------
>tr|A0A0N0B232|A0A0N0B232_9ACTN Uncharacterized protein OS=Streptomyces sp. NRRL F-7442 GN=ADL09_17820 PE=4 SV=1
------------------------------------------------------------------------MHPAGAFARRGPDAYEADPADPTSLRRL
FDALSEDGPVSLDTEWVHALGVSG-PVGPGTLEHARRACLDTTAALAQALTG-DGSPRVWWLSYGARPVVGAVD-RPELALLAGPVEVAPQES-ALNGHW
IDLPDGDLTRWAGHVASVVAD--RPALPRQLALRQGYWWRPDTLPVPDPAGT-RSLVPAGEDTVHLVLGGTGGIGSAVAAWLLEHTRGRILLLSRKPPEE
LSA-----------WAHR----VGLVRADLATMPV-HEVAAR-VADRTPRLDGVVHAAGLGHAGVLVRRDAAAMREAAAVRERGALVV-ERLIAAFPAIA
VYCSSMSAWLGGVGHSDYAAGAGLLGGFAHHRATTETTVRMAIDWDIWSESGMATRVPSADARHQAHLAGLTVEEGKEVFGHALALQLPQLLTDIDAS--
--------------------------------RAFY------GPAEPADRPSRTGPVHR--------------TEGQEE---APGPGGPEERADALARVI
Q-DLLGLDELGPEDSLYDLGADSLTLLSLIDRIEDDYGVEFDLASFSHRVSLAEILKHIEAA----------
>tr|I0J6Y4|I0J6Y4_SORCE Non-ribosomal peptide synthetase/polyketide synthase OS=Sorangium cellulosum GN=pelA PE=4 SV=1
------------------------------------------------------------GRLTGAGQRCVRVFAGEGYEQIEPDLYRIDPGKRGDYARL
LREAFGEEGSCGGVVHLFSLDAAPMEATTAEAAAELVSGSVSAAYLTQALVRH-GFRDAPRLFLVTRGAQGHEAVSVGQAPVWGLGRTIALEHPEVQCTR
IDLAPG--A-SEADAARLARELGAAGPEDQVALRGDDRYVARLVRGRFEAES-ARRFSLRPDASYLITGGLGGLGIALARWMVDRGARHLVLVGRRGPGE
AARG---AIEAMEA----AGARVLVAQADVSRPDDTAGLLATL--DEHTPLRGVVHAAAVLDDHTLLELDEQNFRRSFAPKALGAWNLHALTEGRELDFF
VMYSSALSLFGSPGQANYTASNAFVDALSRERA-RRGLVSMSIQWGAFAEVGLAAADLRGNRLSSRGIASFSPDEGHRALERLLSRPRAEV---------
-----------------GVVRFD--------ARRWATFYATAASSLSRERPS-----------AGGGGRAPRLRQALE--------RAALDERQPLERHI
AEQVAAVPRIDRRAPFPRLGMDSLLSLEVRNRLEASLKLGLSATVMFAYPNIAALAAHLL------------
>tr|A0A0A4AM47|A0A0A4AM47_DICCH Mycocerosate synthase (Fragment) OS=Dickeya chrysanthemi GN=NM75_07660 PE=4 SV=1
-------------------------------------------------------LAEALRARYGDDASVVAAMSAKAFTQHDARRFSVDTQSQASVQTL
CEQLAAQQLWPTHIVHAIGADKHFDDLPVAGPASLLHAGLQSLRHLFVALETVKPGQALRCVNVYTAQAEQVEPQ---QDAVSGYARSINHRFELFTLRS
-D-----ADNAAALANDVYQEFVQPVAGVEVAYRQGIRYQRQAGEITPPDADGMGSQPFVHRGHYVITGGAGKLGLLMAHYLASRYQARIVLSGRSAQPD
ETVQQQ-WV-----AMREHGAEVRYIAADVAQEGQAEALIAQAKAAFG-AVDGVLHCAGVASATPITALSDAEFYALIGPKVDGLVALDRATAQEPLSVF
INFSSVSAVLGDLGSGAYAAGNRFMDSHAVWRNGLRTGQTLSVNWPLWASGQMNIEQEDARLFEFSGMAALGQDAGIIALERALLEQRSALLVAVDRSKV
ARSLRIQAEAMPQTAVSVVTEAP----------RHQPTAAAMQPG-----------------------DSAYLHS--------------ERALKERISTI
T--KLPASDIAVDATFEQLGMDSVMLMELRAVL-EKEYDGLPKTAPFEFNTTAKLA----------------
>tr|B1XKC6|B1XKC6_SYNP2 Polyketide synthase OS=Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) GN=SYNPCC7002_A1173 PE=1 SV=1
--------------------DLNDWLYQVAWTPLDLPPAPEPSAKLWLILGDRQPIEAQF---KNA-Q---RVYLGQSNHFPTNAPWEVSA---DALDNL
FTHVGSQN--LAGILYLCPPGEDPE-----DLDEIQKQTSGFALQLIQTLYQQKIAVPCWFVTHQSQRVLETAVTGFAQGGLWGLAQAIALEHPELWGID
VDDSLP------NFA-----QICQQRQVQQLAVRHQKLYGAQLKKQPSLP---QKNLQIQPQQTYLVTGGLGAIGRKIAQWLAAAGAEKVILVSRRAPAA
DQQ-------TLPT------NAVVY-PCDLADAAQVAKLFQTYP-----HIKGIFHAAGTLADGLLQQQTWQKFQTVAAAKMKGTWHLHRHSQKLDLDFF
VLFSSVAGVLGSPGQGNYAAANRGMAAIAQYRQ-AQGLPALAIHWGPWAEGGMAN------SLSNQNLAWLPPPQGLTILEKVLG---------------
-------A----QGEMGV---FKPDWQ--NLAKQFPEFAK-------THYFAAVIPSAEAVPPTA-----SIFDKLIN---LEASQRAD-YLLDYSVAQI
L--KLEIEQIQSHDSLLDLGMDSLMIMEAIASLKQDLQLMLYPREIYERPRL--------------------
>tr|K9PUU3|K9PUU3_9CYAN Long-chain-fatty-acid--CoA ligase, 6-deoxyerythronolide-B synthase OS=Leptolyngbya sp. PCC 7376 GN=Lepto7376_0247 PE=4 SV=1
--------------------DFSEWFYEVQWHQVELPQASEQKEGLWLILGDHLEIAQQF---PQS-Q---IVSLGDEFQ-QHSDHWEVHP---DQFDQL
FTSLANTK--LAGIIHGWAIAAEEQ-----NLDHSQWLTCYTTLQLIQSLQRQQRQIPCWLLTRNSQAVLENKVEGFTQNSLWGMGKTIALEHPELWGID
LDAAIP------NLT-----KLCNQTKIQHLACRNGSIYCSQLVPQTVTK---TKISAIVPQAVYLITGGLGSIGRRLAQWLDEQGATKVLLLTRRSLAT
DLA-------DLPK------SAIAY-TCDIADDHEVQNLFQRYP-----NISGIFHAAGVLEDGFLATQTWKNFEKVFAAKVQGTWNLHHHSLTNPLDFF
VTFSSVASIVGSPGQGNYAAANGFMDAIARYRQ-GQGLPALNINWGPWATDGMAT------ALRNQGMAFLAPEQGLHILETVLA---------------
-------Q----QTNVGV---FKPDWQ--QLSRQFPAIAN-------SYYFRAVMGETEEVSTQN-----DIFERLQT---LPTTEQQQ-QLTDYSIARI
L--KLDSTQIQPSDNLLDLGMDSLMVMEAIAHLKQDLRLMLYPREIYERPKL--------------------
>tr|A0A060PJW2|A0A060PJW2_9SYNE Olefin synthase OS=Synechococcus sp. NKBG15041c GN=ols PE=4 SV=1
--------------------NSHGWFYRTVWKPIQLGIAQQP-EKQWLILGDREAIYQQF---TKA-K---FVYLGTNNQFSGDDFWQVSP---DSFDEL
FSHIEREH--LAGVLQICPPIVPTS-----DLEQGQRSTSATALKLIQALDQQKFAVPCWFVTHQSQRVLESSVEGFAQAGLWGLGQVIALEHPELWGID
LDTTLP------NLV-----QICQQNQFQHLAMRRGQLYGAQLQPQAHRA---IKKVPVQSQGTYLVTGGLGAIGRKIAHWLADQGAEKIILLSRHRHPK
ISI-------DLPQ------NAIVY-PCDLADESQVEKLFQIYS-----QIRGIFHTAGALADGLLQKQTWENFQAVAAAKVNGTWYLHRHSQNLNLDFF
VLFSSVASVLGSPGQGNYAAANRIMTAIAQHRQ-AKGLPALAIHWGPWAAGGMAT------ALTNQALDLIQPQQGLDILETLLG---------------
-------K----QGEIGV---FKADWS--TLAKQFPDLTH-------SDYFQAVITEEQVPQKNL-----SIFSELLT---LTAEKRAA-YLLEYSVAQI
L--KLDRQKIQPHDSLLDLGMDSLMVMEAIAALKQDLQLMLYPREIYERPRL--------------------
>tr|S5ULG9|S5ULG9_STRC3 Modular polyketide synthase OS=Streptomyces collinus (strain DSM 40733 / Tu 365) GN=B446_04650 PE=4 SV=1
--------------------PLDGALFETRWQPRPEAQ-APPADGGWLILADGTGVADELARRLGDSVPHAVVRQGTAYGTDGPGRHVLDPADPAQWARL
LDEAFADA-PPARVVQLTALDAPP-VTDARAAEEAARHCCLTTLHLVRALTGHRAPAPRLFVVVRGSQPAGDSTTRPEQALAWGFGLTVAQEHPELATTV
IDLPAE----GGD--DRLWTQLRHADDERLVALRGSGRLVPRLARTRPDHDG---ADPGQPDGVHLITGGLGGLGRVVAERLVRQGARRLALLSRGTPDA
AAT-------AFVRDLEERGVDVHLARADVADRAALAAALDAVRAAA-GPVVTVVHAAGVLDDAVLANLTEERVRRVLAPKVLGTALLTELVPEARNLV-
-LFASAAGLLGSPGQGPYSAANAFLDAWAHHLS-LTGRRALSLDWGAWSGVGMVAGSGTRAETGRSGLVAFPPQDGGELFERVLASGRQLAPIALDWDLL
----ALDPDA--ARGRPLLADLITADTDDLVRRVFGATT--AQ-----ERAEWL---------------ETYVRDRVEVSGGAVDV--------------
----------FATTALKELGLDSLMLVRLRNAFARELGVELPAADMFSATDIRGLA----------------
>tr|Q79ZI6|Q79ZI6_STRAW Putative modular polyketide synthase OS=Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB
--------------------PLDGALFETRWQPRPPAQ-EPPATGSWLILADETGVAVELAERLGSSVPHVIVRRGEAFGVEGPGRYVLDPADPQQLAHL
LDEAFADG-LPERVVQLSALDAPA-IGEARTAEQAARLCCLSTLHLVRTLA--DGRAPRLFVVVRGSQAVGDSTTHPQQALAWGFGLAVAQEYPELATTL
IDLPST----DGV--DALWEQLRHADDERLVALRDTGRLVPRLARTRPDDGG---HGELTPDGVYLITGGLGGLGRVVAERLVRRGARRLALLSRGRPGA
DAA-------GWIKGLEERGVTVHLARADVADRAGLTAALAALRRDA-GPVAGVVHAAGVLDDATVANLTDERVLRVLAPKVLGTTLLTELIPEAGNLV-
-LFASAAGLLGSAGQSPYSAANAFLDAWAHHLS-RTDRRALSLDWGAWAGVGMVAESGTRAETSRSGLVAFSPDEGGELFERVLATSRQLAPIALDWEML
----ALDADA--ARTRPLLGDLVTADSDDLVKKVFAATT--DH-----DRAVRL---------------EAYVRARVEVCGGAVDV--------------
----------SGTTVLKELGLDSLMLVRLRNAFARELGVELPAAAMFSASDIRGLV----------------
>tr|T2RMZ6|T2RMZ6_SACER Uncharacterized protein OS=Saccharopolyspora erythraea D GN=N599_36415 PE=4 SV=1
-----------------DLAAVEDWRYRVVWREAPEPSAPASLPGTWLVLVPDAERHQATRAMTECGARAVTVECGEKDT------------DRAALADR
MGRLLSDQPDVRAVVSLLALDERRHPHH-----PAVPVGLAATLALVQVMSDLDRHTPVWMLTRGAVAAGAERLRRPEQAQIWGLGRVAALEHPRQWGGL
VDLPEDPD---DFALRRLCGALAGGGDEDQLVLRESGALVRRLVRAP-VTA--APVRRWRPRGTALVTGGTGALGPEIARWLAGNGAEHVVLVSRRGADS
DGA------AELAAELRELGTEVSFEACDVADRDAVEAMLGRLRAQ-GREVRSVVHAAALMRLAALADTDLREFADVLAAKVEGARHLAELLDPDRLDAF
VLFSSIAGVWGSGDHGAYAAANAYLDAFAEHLR-ADGRAITSVAWGVWDGARFP-EGVDAEQLRRQGLPLIAPGPALTALQQVLDHDEAVSVADVDWDRF
VSLF------------------TSA----RPRPLLDEVPEAA----------------PAPADDGQDEPGSSWPERLAAL----GEADQRAALRALVREQ
AAFVLGHESIDDGRAFRELGYDSLTAMELRNRLNAATGLRLPATLVFDHPTPAAVAEHLRSRLVRT------
>tr|A0A0F5A3H8|A0A0F5A3H8_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. MUSC164 GN=VT50_32375 PE=4 SV=1
-----------------VRSVVDGWRYGVMWKPVAGRLAAGVLGGCWLVVVRAGEAGGGVGMLAGCGVDVRVVELGAVGR------------GG--VAEE
LR----ADGSVAGVFSLLAVGG------------D-ELGLLGTAVLVQALGDVGVGGSLWVATRGGVSVGSDGVVVPGQALVWGFGRVAALELPERWGGL
VDLPESE-------LGRLAGVLAG-SGEDQVALRASGVFGRRLTEASG---ATPDDEGWRASGSVLVTGGTGALGAHVARWLVANGAEHVVLTSRRGLDA
PGA------VELRDELAASGARVTVAACDVADRDALAELLASIPA--EFPLTTVFHAAGVLDDG-VDTLDAERLERVVRAKATSAQNLHELTRDLDLSAF
VLFSSLAGSVGAAGQANYAAANAYVDALAELRR-AEGLPATSIAWGPWAEGGMAADEALERRMRRDGVPPMAPESALTALRQALDLDDTATVADLDWGRF
LAEF------------------TAV----RPSALFGEVRAAR----------------PAPVAEAAGVGTGTLAERLSGL----TENERTQTLLELVRTQ
VASVLGHEAVEAGRAFKELGFDSLTAVELRNRLNAATGLRLPATLIYDYPNATALADHLRGEL---------
>tr|A0A081E9A3|A0A081E9A3_STRFR Uncharacterized protein (Fragment) OS=Streptomyces fradiae GN=SFRA_32280 PE=4 SV=1
-------------------------------------EPASSPSGHWLLVTPPTPEGRR-GALARQGATVERLVVDPVAV------------GRDGLAAR
LGE------RWDGVLSLLGADERPLPRH-----PALNRAVMGTTLLAQAALDAGCEARIWAVTREAVAVSS-EVPRDAGAQLWGLGRGIALEHPSLWGGL
IDLPAVPD---ERAWARAVRRLV--HGEDQIAVRASGAYGRRLLPAPPAA----SRRTCTPSGTVLVTGGTGALGGHLARRLARGGTGHLVLTSRRGPDA
PGA------GELAGELASLGAKVTVAACDMADREAVRALLDEHRP------TAVFHTAGTPHSAEFTALDETTTAGVYGGKVLGARHLDELTRELGLDAF
VLFSSGAAVWGSGGQTAYGAANAALDALAERRR-AAGLPATSVAWGLWGGGGMG-EGDGEEFLSRRGLGVMPPEDALEALDRALDREDTTVVADVDWERF
APAF------------------TAF----RPSALISRLVSDG----------------GEAGG-QDAPDGTLFAAGFAAA----GPLERQEMLLGLVRRH
VAAVLGHADIGPDRAFKELGFSSVTAVELAGRLGRECGRKLPPTLVFDHPTAAAVAEHLAELLTPP------
>tr|A0A0F4ISC9|A0A0F4ISC9_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. NRRL S-495 GN=VR45_41030 PE=4 SV=1
-----------------------PQRYRIAWEPLTAPA-QPALSGRWLLVTPD-----ACQALAGHGADVVVIRVGAA-V------------ERAE----
LALLLPE-GALEGVLSLLALAEGPHP---------LDAGLTGTLLLLQALGDSGIDAPLWCATRGAVAART--EVRPEQAQVWGLGRVAALEHPQRWGGL
VDLPDLG------ALDGLCAVLAG-DGEDQVAVRGPEALGRRLVPAPAPAT--PTPAPWTPRGTVLVTGGTGGLGAQVARWLAERGAEHLVLLGRRGPEA
PGA------DALVDALAALGARSTLLACDVADRAALERVLERLSDE-GDTVRAVVHAAGLTSDTALMDCTPEELALRTAAKTRGAAHLDVLFEGRPLDAF
VLFSSISGTWGSGGQGAYAAANAYLDGLAAARR-GRGLTATSVAWGPWAGAGMA-DGAVGDGLRRHGLVPMAPAAALSALGLALALDEGEVVAELDRARF
VPTF------------------GSV----RDSALLRGLPAAA----------------ESRAADPGTGGDPSLLQRLRRL----SEPEGRKLLTELVRSE
AAVVLGHAGFVADRPFREVGFDSLTAVELRNRLVAATALPLALTSVFDHPTAAALGAHLFAGLSGT------
>tr|A0A0L8QDG2|A0A0L8QDG2_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces varsoviensis GN=ADK38_38450 PE=4 SV=1
---------------------------DVYKRQLAVPP-APDLPGTWLLVVPEDGATGACEALVRHGAEVSVLRVAAG-T------------GRAE----
LAGLLPARSDVVGVLSLLAFADAEAHAD-----AHPSAPLAATLTLIQALGDRELNAPLWCVTSGAVAPVPSVPIDPVQAQIWGLGRVAALELPRLWGGL
IDLTGAGE---DGALDGMCAVLGG-DGEDQVAVRGARLFGRRLDRASVPAR--PAAEVWKPRGTVLITGGTGGLGAHVARKLAAEGAEHLVLLSRRGPRS
PGA------AELTAELSALGARSTVLACDVADRAALTRVLDGLRAE-QETVRAVVHTAGLTSDTRIEHCTPDGVARETAAKTRGADHLDALFDSPSLDAF
VLFSSISATWGSGGQAAYAAANAHLDALAAARC-ARGLAATSVAWGPWSGAGMA-HGDVGRRLRRHGLVPMEPAAALDALQRALTYGESEVVADMDWQGF
LPAF------------------LSA----RDSALLRRLPDAA----------------PAATAGSGADAHDAWRRALAEL----PPDERGHRLRELVRAE
AAEVLGHGSIDADRPFRDAGFDSLTAVELRNRLIAVTGLALPLTTVFDHPTATALGDHLLAELTVA------
>tr|A0A0N0YGC3|A0A0N0YGC3_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. NRRL S-4 GN=ADK82_27980 PE=4 SV=1
-----------------NGSVIDGWRYRIDWTPLARAK-SSSLSGQWIVLIPEALRDDACAALAEHGARVTTLVVSAGES------------DRDTLAGS
IRRLLDAGGEVAGVLSFLGADETPDPVH-----AAVPAAVTSTLALVQALDAVELQAPLWCVTRGAVQVSTDRTVSVAQAQVWGMGRVVGLERPGNWGGL
IDLPAEVD---ARITDSLCGILSDAAGEDQVAVRTAGVFGRRLARAPLNGA--DPTAPWNAEGTVLITGGTGALGGHVARWLAGRGAERLVLTSRRGTAA
PGA------AELEAELTALGTKVSVVACDVSDRAQVAELVGRLSQE-GSPVRSVIHTAGISDSVALADTEPAAFADVLSGKTAGAAHLDELLG-GTLDAF
VMFSSIAGVWGSARQAAYATANAALDALAIRRR-AQGWAATSVAWGQWADSGMA-AGETGEQLTRLGLAPMDPGLAVAALQQAIEHDEAPVTVDVDWSRF
ATAF------------------TTL----RRSPLIAGLPEVR----------------AALTSTEGAGTADALTRRMLDL----SGPERDHLLLELVQER
AATVLRLNAVRPDRAFRNLGFDSLTAVELRNQLAEATGLRLPAALVFDHPTPTALITYLRGKLLPE------
>tr|A0A0N0YEZ6|A0A0N0YEZ6_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. NRRL S-4 GN=ADK82_24295 PE=4 SV=1
-----------------EASATDSWGYRSSWTPLAEGSA--SLTGTWLVVTSATGASNLIHAMRAQGAEVLHCAAGDVL-------------DRVTLS--
-L-AGTLRTDIAGVLSLCSVDEEPVAGS-----PE-TTGLAATVTLVQALGDTAVAAPLWCLTQGAVQTSHDGSISPAQALVWGMGRVAGLEHPERWGGL
IDLTDAE-------LSRLCGLLARACDEDQLAVRPGGVFARRLLPAPP---V-ASGRSWTPEGTVLVTGGTGAIGRQLARWLCGHGAEHVVLIGRRGADA
PGA------AELIEELAGPGTKVTAVACDVADRDALAGLVARLTAD-GDRITAVLHGAGELDDA-MGALTPERLAAALRANVGGARNMQEVTQGLELTAF
VLFSGIAGTVGGAGQGAFAAASAYLDAFAAHRR-SRGLAATSIAWGPWADGGPATDDTFVERMGRRGLAALPTASALPALSRAVAQDSPSLLADIDWALF
GPSL------------------TAV----RPSPLIADVPRMR----------------EITRAA----SAAVFRRTAAEL----SEVELGQMLLELVRTE
AAGTLGHEAVGAKRPFRDLGFESLTAVELRNRLSTRTGLRLPVTLAFDYPTPVALAAFLRTEVGDD------
>tr|A0A0N0HJ24|A0A0N0HJ24_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. NRRL S-4 GN=ADK82_24480 PE=4 SV=1
-----------------ERTDLGELCYEVNWRPLAEPAA--QPTGTWLKITAGGTAAAECATLERQGLDVVTVDVSADLE------------GPDALAER
LRA---VDTPVRGVLSLLALAEGPGDAW-----P-----LTATHALVRALGEADVPAPLWCVTQGAVAVA--EETRPGQAQVWGLGRVAALEHPERWGGL
IDLPEEA-------TARLGAVLAG-TGEDQVALRVGGLLARRLRRAPL---ATADGVGWTPRGTALVTGGTGALGAHVARWLARSGVEHLVLTSRRGRQA
PGA------AALEAELAALGARVTIAACDVADQGALDALLGELDAD-GVRVTSVLHTAGVAQTS-IDETQAHDVTAISAGKTDGARHLDEAFGDTELDAF
VLFSSTAGIWGGAGQGAYGAANAYLDALAERRR-ARGAVATSVAWGPWSEGGMAARDDAEAHLRRRGVRALAPATALSLLRHAIDQRVTCTVADVEWETF
ALSY------------------TST----RPSNLLSDIPEAL----------------RAQAPA-AGDGAEELVRRLSGL----SGADRQQALTELVRTH
AAVVLGHAAIEADKPFRDVGFDSLAAVQFRNRLAEATGLAVSATSVFDYPTPAELAEHLRSELGQG------
>tr|A0A0F5AE34|A0A0F5AE34_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. MUSC164 GN=VT50_13230 PE=4 SV=1
-----------------EQSTVDGWRYRVTWTSLTEAQ-APRLSGTWLLAVPESAATDGARTLTERGAEVRQITPTAVES------------DRASLTRL
VR----LAGAVSGVLSLLAFDAGTAPGT-----DG-SAGLVGTAVLIQALGDAGVDAPLWCATRGAVAVGTDTVESPEQALVWGLGRTAALEYPERWGGL
VDLPGAE-------LARLAGALAG--GEDQLAVRAAGVFARRLAHAPL---AAPAVRSWKPYGTTLVTGGTGALGAHVARWLARNGAEHLVLTSRRGPEA
PGA------AELRDELAELGADVTIAACDVADRKAVETLLAAVPA--DRPLTAVMHAAGVLDDG-LDALTPERFATVLGPKADAARHLDELTRDLDLTAF
VLFSGIAGTLGDAGQGNYAAANAYLDALAERRR-AAGLPATSVAWGRWGETGLAADGAIGERLDRGGVPAMAPHAAITALQRALDHADTVAVADIQWDRF
AHGY------------------TAV----RPSPLIGELPEVK----------------RLRETGADGSPADALRNRLAGI----SRAEQSLVVLEVVRSG
AAAALGHDEVGAGRAFKELGFDSLIALELRNRLTAATGQKLPATLVFDYPTPAALAEFLCGRIVGD------
>tr|S3ZCD7|S3ZCD7_9ACTN Putative Oleandomycin polyketide synthase, modules 5 and 6 OS=Streptomyces aurantiacus JA 4570 GN=STRAU_6150 PE=4 SV=1
-----------------ENSTIDRWNYRESWTPLNETT-AGTLSGDWLVVVPEGRADSAVALLAEHDARPVTVEMPASAT------------GRDAVAAV
LR-VGGPAAALTGVLSLLAADGGAPQGS-----DTASAEAALTLALIQALGDAGVGAPLWCATRDAVAVGADARTAPARTALWGLGRVAALEYPERWGGL
VDLPDAT-------VSRLGRLLGG-AGEDQVAVRGSGAFGRRVVRAPLD--G-GTAGEWAPRGTVLVTGGTGALGRHVARWLAREGADHLVLTSRSGLDA
PGA------PELRTELEELGVRVTVAACDAADREALARLLDGISSENGAPLTAVFHAAGVLDDG-LDAMTPERLDTVFRAKAESARNLDELTAGLELSAF
VLFSSFAGVAGGAGQGSYAAANAFLDGLAHARR-ARGLTATSVAWGPWAGSGMAAEGVAAERLRGGAIPPLEPDHAITALKRLLAQDRTALVADIDWQQY
APAF------------------TAG----RPSRLYVELPEVE----------------RLSATAAAGQGP-DLVAKLASL----QRPEQERLLLDLVCEQ
VAAVLGYAAVEPTRAFRELGFDSLTAVELRNRVNALTGLVLPATVVFDHPTPTALADCLRTELAPD------
>tr|A0A060ZJ32|A0A060ZJ32_9ACTN Acyl transferase OS=Streptomyces iranensis GN=SIRAN156 PE=4 SV=1
------------------ATGETDSRYRVAWAPVADRKA---TPRAWMVIVPEEPTKASYGALADAGLDVTTVTLDRVA---------------------
-------GNLAQGVLSLLPLGNGTGLEN-----------AAQLAATVRVLASMGNRAPLWVVTRGATGPG--VPEAPEQAMVWGLGRSIGLETPDTWGGL
IDIPADP-------WRLLAGAL---GVEDQIAVRTSGVFGRRLIRATD------TGRGWRPRGTVLITGGTGAVGVHVARWLAERGAERLVLVSRRGGDA
GEL------A------DSVGVPVEVVACDVTDRAAVAALLE------GRDLTAVVHAAGVLDDG-AGTLTPDRFAAVAGVKVDAVRHLHELTRESGLDAF
VVFSSLAGVIGSPGQGNYAAANAAVDALAEAYR-GQGFPVTSIAWGLWGESGAAD-GHSGRQLTARGIPPLDPARLLASLDWAVGQGDAAAVARIDWDRF
RLFH-------------------------GSTSLYDELLEAR----------------PGPETG-------SAAQSLAEL----PPAERDRALLDLVRGE
AAVVLGHALIDPGTAFRELGFDSLTAVQLRNRLAAVTGLDLPSALVFDYPNVTALAGRLRALLAPD------
>tr|A0A0Q8ZDX6|A0A0Q8ZDX6_9ACTN Modular polyketide synthase (Fragment) OS=Streptomyces sp. Root264 GN=ASE41_32385 PE=4 SV=1
------------------RAKLDSWRYRVAWRPYQLPE-EAALDGTWLLVVPERWTDDRARVLEEATRVILVVVPERAD--------------RTVVAEL
LEA---VGDAPAGVLSLLALDDTPDKRS-----PG-TRGLLGSMALSQALADNAIHAGLWSLTRGAVAVDGDEPV-AGQAAVWGLLRVAALDDPERSGGL
VDLPVDT-------LSRLPALLAA-GGESEFALRPRAVHVRRMVRAPL---ASVEAPVWQPRGSVLITGGTGALGAHVARDLAREGAEHLVLTSRRGPDA
PGA------AELERELTDLGCRVTIVACDVADRGALAEVMRGIPE--ETPLTAVVHTAGAVDRAPLTKIDADEAVELMHAKVVGAENLHELLGAQPLDAF
VLFSSGAGVWGNGGQGPYAAANAHLDALAERRR-AVGLPATSIAWGAWAGGGMVD-AEVGEQLARRGVPAMEPALAVRALRESVAADETTVVADIRWDRF
VPAY------------------CAH----GHRPLIDEIPDVQ----------------TLPAAQDASTAADGLRGELAAL----PAAKRKRRLAELVRTH
VVAVLGSDVVRPGRAFRDMGFDSLTAVELRNRLGSALGAKLSATLVFDHPTPNALADHLGAELFPE------
>tr|J1ZMI3|J1ZMI3_9ACTN Acyl transferase (Fragment) OS=Streptomyces auratus AGR0001 GN=SU9_32733 PE=4 SV=1
---------------------------------------------------TES---DWVDGLLEAGCSVVDVLVDTTDT------------DTAAVTER
LKQ---AGPEPVGVVSLLAFDGRHDTAC-----PS-PRGTAATLALVRALGDAGITAPLWCLTQGAVTTSGDRLGAVEQAQIWGLGRVVALEHPDRWGGL
VDLPSTP-------RTQLCAALGS-TDEDQLALRPVGILGRRLVPDRGDRPA-ARTAPWEPAGTVLITGGTGALGAHVARWAAAQGVGHLLLAGRRGADA
PGV------AELRADLEASGASVTVAACDVADRRAVQELLDGIPA--RHPLTAVFHAAGVLDDG-IADLDTERLETVLAPKTEGARLLDELTRDTELSAF
VLFSGFAATVGSSGQAGYAAANAHLDALAQRRR-ADGLPATSIAWGPWTGGGLVD-EGIEERLLRRGLSAMEPRLAVLGLSALLSDGPANALVDVDWRRF
LPSF------------------TAS----RPSPLLREMAQPS----------------QADPGAAGGGAGPTLAERLPGL----TGGERDRLLLTTVRAQ
VASTLGYDAVSPRQQFKELGIDSLTALELRNGLQAVAGVALPATLVFDHPTPEAVAGHLSRTILGD------
>tr|A0A0C2AUT3|A0A0C2AUT3_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. AcH 505 GN=HY68_28805 PE=4 SV=1
-------------------------------------------AGRRLVVVPAGSADDAVAELG---PDTVLFEASADGA------------DRTLWAKR
LAELTSEGTEFAGVLSLLAPAEERHPDF-----ASVPCGLALTLALVQALGDAGLDAPLWCATRGAVSVGDDRLTSPVQGALWGLGRVVALEHPDRWGGL
VDLPDTLD---ARAGARLTAVLAGVDGEDQVAIRGSGLYGRRMTHAAPAVT--TPERPWRGRGTALITGGTGGIGGRVARWMAESGAAHLVLTSRRGEEA
PGA------AELRSELEELGAKVTITACDAADRTALAGVIGAIPA--DLPLTSVFHSAGVADGDSVATLTLRQLDALMRSKLTAALHLHELTRGLDLDAF
VLFSSGAAVWGSGGQPGYAAANAFLDALAEHRR-AEGLTGSSVAWGTWAEVGMATDAEVGERLRRQGVRAMEPALALAALQRMLEDDDTATVASMDWEVF
TPSF------------------TAT----RPSPLLAVISEAG----------------QALATDDTETGVPPLRQRLDAL----PTAERARALLEAVRAE
AAATLGHDAVAANRAFRDVGFDSVTAVELRNRLRTGLGLPLPAALVFDHPTPDALARHLGPLIFGA------
>tr|A0A0D5XQ49|A0A0D5XQ49_9ACTN AstD5 (Fragment) OS=Streptomyces sp. XZQH13 PE=4 SV=1
-----------------DQAVLDGWRYRIDWQPVTDRLGATAADGTWLMLVPAGHTGS--GALTAHGGRVVRVAVD--GE------------DRKGLAEL
VRAVGLDGDAPAGVVSLLPLDERPDTEH-----PTLSRGTAATVTLVQALDDLGVTTPLWCLTSGAVAVRDGEVRSATQPMIWGLGTVLALDHPRTWGGL
VDVTAEPD---TTELGRLVAVLCGEHGEDQVAIRPAGAYARRMVRAEPLAETTASADGWTPRGTVLVTGGTGGIGAHVARWAAGRGAEHLVLLSRRGRAA
DGA------DALEAELTALGARVTVSACDVTDRAALAEVISAVPS--DLPVSAVFHAAGTAQEPRLPESTVAEFAEVGRAKIVGAVHLDTLLADHTLDAF
VVFSSGAAVWGGAGQSGYAAANAYVEGLARRRR-AEGRAATAVAWGAWAGGGMV-DDAVAEEFAEVGVELMRPELAVQALGQAMTRDEGHVVAGIDWSRF
VPAY------------------TAA----RQRPLLRELPEAT----------------ALRATG-AGDEDGALRTLLLPL----SPQERLTALTDLVLTE
AGQILGHTAIEDGVAFLDIGFDSLTGLELRNRLDRVSGLDLPQGLIFDAPTAGMIAELMLEALEPE------
>tr|A0A014MJ12|A0A014MJ12_9ACTN 6-deoxyerythronolide-B synthase (Fragment) OS=Streptomyces sp. PRh5 GN=Z951_46725 PE=4 SV=1
-----------------DQSTVDSWSYRIAWDPVATGE-PPILPGTWLVVVPSPQADDGVAALAEHGADPVVVEVD--TV------------ERAELTAR
LRERMSDDDEYAGVVSLLAWDERIC-EP-----GTLSRGVAATVALMQAVEEIGLAAPLWCVTRGAVAVRLSEVTSEFQPLVWGMGVVQGLDQPSTWGGI
VDLPQTPD---GSTLARLCAVLAGVDAEDQVAVRASGVFARRMRREPV-----TSAPVWQPRDTVLITGGTGGLGSYVARWAAGHGARHVVLLSRQGAQA
PGA------AELEAELTALGSDVTIAACDVTDREQLAAVLAELPD--GAPLSAVVHAAGLALPEPLSKITLAEFADIGRAKIAGARHLDDLLWERELDAF
VLFSSGAAAWGSGGQSAYAAGNAYLDALAQRRR-ARGLAATSVAWGAWGGGLGTIDEMMGAQWRRTGLMTMDPRLAALAMAHTVGSGTAHVVADIDWERF
APGY------------------TMA----RFRPLLRGLPDVI----------------DLLAEDG----QSELVARLAGL----RPEDQERLLTELVQAE
AAAVLGHDA-TGDRPFSEIGFDSLTAVELRNRLNTATGLRLPATMVFDHPRPSVLARRIRAELGQT------
>tr|I0UWU6|I0UWU6_9PSEU Uncharacterized protein (Fragment) OS=Saccharomonospora xinjiangensis XJ-54 GN=SacxiDRAFT_0064 PE=4 SV=1
-----------------DRERVDSWRYRVRWTGVPMLEASAPLPGTWLLVDVDPAAGQAAEELLVQGGAQVMRIGIEPGL------------GRVALATR
LRRLVEAEPSPAGIVSLLGLPRPADPVP-----PTLPVDLVSAVTLVQALGDAAVTAPLWCLTRGAVSTRDDPPADPTQAMLWGLGRVVALEHPERWGGL
VDLPSLLA---ARIGSRLRGVLAGESGEDQVAVRPAGVFGRRLVRAPLGTDVARAAECWRTRGTVLVTGGTGALGVRVARWLASRGAERLVLISRRGPAA
PGA------AELVAELAAVGVETVVVACDVTDRDALREVLDDIPP--TTPLTGVVHTAGVLDDTALTDLSESRIAEVLRAKTQGLATLHQLTRHHPITAF
VSFSSISGVWGSGSQGAYAAANAAADAIAEQRR-AAGLPSTSIAWGAWAGSGMA-SGEAGDYLRRRGVLPMSPEEAMAALEASVGNDDMAAVADVDWANF
VPSF------------------TLH----RPQPLLSELPEAQ----------------QAVNSTGDGDERDDLVRQLTAM----PPGERARAVLDLVRSE
VASVLGFDQVDPDAAFQSVGFDSLIAVELRNNLSRSTGLPLPPTLVFDHPTPASVAEHLGTRLSAE------
>tr|A0A0F2SQG6|A0A0F2SQG6_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces rubellomurinus subsp. indigoferus GN=VM98_31895 PE=4 SV=1
-----------------ERAAVDAWRYRITWQPVPEPAAA--PPGRWLLVVPQGIAGEC-EALYAAGATVDLLAVDAATA------------DRTELAER
------LTAAVDGVLSLLAVDGRPRPDA-----PD-TAGLAATLALLQALGDAGVEAPLWCATRGAVSA-ADRPVDPRQAQVWGLGRVAGLEHPRRWGGL
LDLPERA-------GARLAAVLAG-TGEDQLALREQGLLARRLVRDATAGPYGPAPQPWRPSGTVLVTGGTGALGARVADWLACGGAEHLVLASRRGPDA
PGA------ADLAARLTALGATVTLARCDVGDRTAVARLLAELPA--EPPLTAVVHCAGVLDNA-LDSADPAHLARVLAAKAGGAAHLDELTEGIPLDAF
VLFSSNAGVWGSGGQGGYAAANAHLDALAERRR-ARGLPATAVAWGAWADTGLAARETERAYLDRRGVRAMDPDLAIVALQRALDEDDGCAVADVDWRRF
AASF------------------TAL----RPSPLLADLPEAR----------------PAEEEA----PPGDAAAALRGL----PAAEQHTALLDLVRAH
AATVLGHDAVPATRAFKELGFDSLAAVQLRNRLAAATGLTLPATLVFDHPTPEALARHLRTGLADD------
>tr|A0A0F4ISF3|A0A0F4ISF3_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. NRRL S-495 GN=VR45_40780 PE=4 SV=1
-----------------ERSVVDSWRYRVTWRALPEGP-PAALDGNWLVLSSDGRSEDATHVLEQAGASVVHLRTTEAEA------------DRAVLADR
VRASLDAPGPVTGVLSLLGLDERPHSAH-----PSVPLGTALNLALVQALGDAGTDAPLWWATRGAVSVGTGGPVSAAQNLLWGLGRVAALEFPQRWGGL
IDLPEVP------AAARLCRVLAGGGDEDQVAVRATGCHGRRLVRSALGDT--EPRRRWRPGGTVLITGGTGGIGAQIARWLARRGAGHLVLVSRRGADA
PGA------PELSEELAALGARVTLASCDVGDLEALRALKDGLEHD-GHRISTVFHAAGAGLLVPLPDTDADEFADTFHAKAGGARNLDLLFDRDTLDAF
VLFSSISGVWGSAVHGAYAAANAYLDGLAEDRR-SRGLAATSVVWGIWNGAGMA-AELAEETLRGHGVLFMPPAVAITGLQQVLDHDETVVVADIDWDRF
ATVF------------------TSA----RPSPLIGELPEVR----------------AALAAEGAEGAPSALRDRLAPL----PAAERTRTLVDLVRTH
AAAVLGHDAVAPGRAFRDLGFDSLTAVDMRNRLNTATGLRLPVTVVFDYSSATALARRLETGLLGA------
>tr|A0A0A0NIY2|A0A0A0NIY2_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces rapamycinicus NRRL 5491 GN=M271_13820 PE=4 SV=1
-----------------AASTMDAWRYREGWRPLPDTA-SSALSGTWLVVLAPDQKGDAITALDRHGATVETVVVAPDD--------------PRRWADT
LAAHTTATAPVVGVLSLLARDE--------------AAGLHRTLRLVQGLEAVGLFAPLWCVTQGAVSVGHDPLTGPAQALVWGLGRVAAQELATRWGGL
VDLPQEE-------TVRLCAVLAA-GHEDQVAVRATGILGRRVVRAPR---LDVLDDGWSPPGTVLITGGTGALGSQVARRLAARGAEHLLLVSRRGDTA
PGA------DELVAEVTASGAKATVAACDVGDADALRALLASIPP--AYPLTSVFHTAAVLDDA-ITSLTPEQVDRVLRVKADAAWRLHELTRDLELSAF
VLFSSLAGTVGMVGQGNYAPANAYMDALARHRR-SRGLVATSVAWGSWAQGGMAERDAVTELRLRHGVPLLPPESALLALEAALADGETAVIADIDWDRF
AHAY------------------TAA----RPSHLLDEISEAR----------------RALGAVGTGDTAAALRDRLADA----KPEERERRLLEAVRGQ
VAAVLGHEAVGTRRPFLELGLDSVTAVELRNRLGSVTGLQLPATVIFDFPTVAELVDYLSAQLFSG------
>tr|A0A0N0YE67|A0A0N0YE67_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. NRRL S-4 GN=ADK82_29745 PE=4 SV=1
-----------------EAASMESWRYRTHWKSLPAGP-KAALSGTWLVAVTPGQLDGTVGALRAQGAVVEPLVVSGADD------------AERPWAEA
LAA------AASGVLSLLAQDESPLTDA-----SA-PAGYAQNLALLQQLEAADSDAALWCVTQGAVSIGRDPLTSPAQALVWGLGRVAAQELPTRWGGL
VDLPREE-------LARLCEVLAA-AGEDQVAVRSTAAYGRRLVRAP----LGALGDGWTPKGTILITGGTGALGSEVARRLAAQGAEHLLLVSRQGGTA
PGA------TDLEAELAATGARVTTVACDVADPEALRHLLDSVPE--DCPLAAVVHTAAVLDDG-LTTLTPEQLDRVLRVKAGAAHQLHEMTKDVGLSAF
VLFSSLAGTVGMAGQGNYAPGNAYLDALAQYRR-AQGLVATSVAWGSWARGGMAGRDVVADTSIRHGVPLLQPERATAALETALAHGDTSVIADIDWERF
AYAY------------------TAA----RPSRLLDELPEAR----------------AVLTRD--VTATLTLSERLAGL----APAERERQLRTTVRTQ
VAAVLGHETVELRRRFLELGLDSVTAVELRNRLSSATGLRLPATIVFDCPTVHELVRYLGDTLFGG------
>tr|I0J6Y5|I0J6Y5_SORCE Polyketide synthase OS=Sorangium cellulosum GN=pelF PE=4 SV=1
----------------GAMDALEGCACEVAWRRVEPLEATLPEEGAWLVFSDQRGVGAALKARLARAQRCVRVVAGTSYERVEPDLYRIDPTKPGDYQRL
LREALGEEGSCRGAVHLFSLDAAAVEASAETLSADLGRGSVSAAYLAQALVRHRDAPRLFLVTRGAQAVEEGEPVSVGQAPLLGLGKTIALEHPELRCTR
IDLSAAGGE---GEAELLARELGARGREDQIALRGEGRCVARLVRSSFEPAPREAAIALRADRSYLITGGLGGLGLSLARWLVEQGARHLALVGRRGPGP
E---AQQAIREME----EAGAQVLVASADVSRRDEVERLFARVEER-LPPLCGIVHAAAVLDDHTLLEQSEESFRRVFGPKALGAWHLHALSEGRALDFF
VMYSSASALFGSPGQGNYAAANALLDALARERE-RRGLRSMSIQWGVFAEVGLAAAQDRGKRLSSRGMGSFTPVEGLEALRRLLLNPRAEVVVRFDPRQW
L------------------ELYPGTS----GPPFLAEVMAEDT-------------------SHRGAGAAPRALERLKS----APAGERPALLERHLLEQ
AGSVLRLSKMDRAASLQSLGMDSLMSLELRNRLEASLGIRLSATILFTYPTAGALAEHLLDRL---------
>tr|I0J6Y7|I0J6Y7_SORCE Polyketide synthase OS=Sorangium cellulosum GN=pelC PE=4 SV=1
----------------EEQDALDGCVYEVAWRQAEPLEPSFPRGGAWVVFSDQGDVGAGLHVRLGAGQRCVRVFAGPGYERIEPDLYRIDPAKPGDYQRL
LSEALGEEGLCQGVVHLFSLDAAPLEATAETLSADLVRGSVSAAYLTQAIVRHRDAPRLFLVTRGAQAALEGEPVSVGQAPLLGLGRTMALEHPELKCTR
IDLSATAAE---GEAESVARELGARGREDQIALRREGRYVARLVGGALD---RPAPPGVRADGSYLITGGLGGLGLSLARWLVEQGAKHLALVGRRGPGP
E---AQQAINAME----QAGARVLVESADVSRRDEVERLFARVEEK-LPPLCGIVHAAAVLDDHTLLEQSEESFRKVFGPKALGAWHLHALSEGRALDFF
VMYSSASALFGAPGQGNYTAANAFVDALSHERA-RRGLASMSIQWGAFAEVGLAAAHERGKQLSHRGVASFTPAEGLEALRRLLLNPRAEVVARFDVRQW
I------------------EFYLAAA----GLPMFAELIAQRA-------------------SARGDREAPRLRETLAE----AAPHERLTLLERHLCEQ
AAIVLRLSQTDPRAPFQSLGMDSLMSLELRNRLEASLGLRLSAILLFTYPNPATLAGHLLAAL---------
>tr|L7UC18|L7UC18_MYXSD Polyketide synthase OS=Myxococcus stipitatus (strain DSM 14675 / JCM 12634 / Mx s8) GN=MYSTI_04325 PE=4 SV=1
----------------RVSAELADWMYQVGWEAQ-ALEPPEKSPGTWVLFADSRGVARELRGLLARGESCVWVTPGASYRSVGEGAYEVDPRDAEHVRRL
LSDALPSAPVCRGVVHLWSLDSAPNDANPQTLERARHQGTTAMLHLVQALARARDAPRLWLVTQGARSVGPRERVSVAQAPLWGLGQVIAMEHPELRCTR
VDLSTDA-A---GASDALFRELSSASPEDQVALRDGARHVARFLRAAEVP--RDSSARVVADGTYLITGGLGGLGLQVARWLVEQGARHLVLLGRAAPST
D---AEATLGQLR----EAGTRVEVVRADVSSPEDVARAMAVVDGA-MPPLKGVMHAAGLLDDGVLLNLTEERFATVMAPKVLGAWNLHEATRQRPLDFF
VLFSSAAALLGSPGQGNYASANAFLDALAQARR-AEGLPGLSIAWGAWTGIGLAARASQ--RIEARGLRGMSPDKALAALGLLLGQDRPQVVVSLDLRQW
M------------------EFYLSAA----QSPFFARLAGQLS-------------------SRPSDSGRGKFREKLEQ----AGGSERRALLERHLREQ
IAAVLRMERLGPRVALGSLGLDSLMGMEIRNRLEASLGLKLSATLVWAYPTLVALVAFLSERL---------
>tr|I0J6Y6|I0J6Y6_SORCE Polyketide synthase OS=Sorangium cellulosum GN=pelE PE=4 SV=1
----------------AARDPLDECVYAVEWHRGELARAASPRGGAWLVFLDQKGTGTALRELLARGEASVGVLPAERYARLQPDLYQIDLAEPEHYRRL
LREAFGDEEACRGAIHLFSLDAAPWEQTAETLDADVTRGSLSALYVAQALLRRRDAPRLWLVTRGAQKVGAGDGVAVSQAPLWGLGRTIALEHPELRCTR
VDLSPAASA---EEVTALVGELWSQDGEDQIALRDHGRHVARLVQTNFNR--QERGVRVRPDGAYLIAGGLGGLGLTVARWLVEQGARHVALMGRSAPSA
A---AEEAISAMK----AAGAEVLVVRADVSRHDDVARTLAEIDAR-LAPLRGVVHTAVNFDNHPVLGLSEEHFRRALSAKMHGAWNLHALTSSRECDFF
ILYSSVSVLLGLPGLGNYLAANAFLDALAEQRQ-RAGLCGMSIQWGVFSEAGVAAARDSSQSLSDRGLGSLTPIEGTRALSRLLGRPAPNVVARLNARQL
F------------------EFYTLMA----QIPFYSRLRQDSA-------------------ASAGAGEAGRFRRTLDA----AAPGEQRKLLEEHLREQ
VGKVLHMARIDRDAPFSGFGMDSVMSLELRNRLEVSLGLKLSATLLFTYPSLAALATYLMTAL---------
>tr|L7UGQ3|L7UGQ3_MYXSD Polyketide synthase OS=Myxococcus stipitatus (strain DSM 14675 / JCM 12634 / Mx s8) GN=MYSTI_04326 PE=4 SV=1
----------------GARDALEGSVFTVAWQRTEALDA---ASGTWLVFSDRGGFGEELQSLLTRGGACVGVVAGSAYERVSADLYRINPASPEDYRRL
LRESFGEDGRCQGVVHLLGLDAAAFSSTSATLASDLSHGAVSATYLAQALVRQRDVPRLVLVTRGARSVVEGDAVAPAQASLWGLGQTLATEHPELECTR
IDLAPVPDA---RDASLLLSELVAKGHEDQVALR-EGRHVARFVRGGFEPPP-AARPGIRADASYLITGGLGGLGLSVARWLVEQGARNVALVGRTAPSA
R---AEEVIRTLE----AAGARVRVSAADVSREEDVERLLAELGAN-LPPLRGVVHAAGLLEDHTALELSDAHFHKVAAPKIQGAWNLHARTLGQPLDFF
ILYSSAAVLLGSPGQGNYAAANAFMDALAEQRR-ALGLPAMSIQWGAFSEVGLAAAVDRGDRLSYRGVGSLTPAEGITALSRLLEHPRPVVVLRLDARQW
F------------------EFYPRTA----SVPFFAELPREAA-------------------PRSGSAQGTSLKQALES----APPAGRLDLLEGHLREQ
LGRVLRIARIDRTAPFKSIGVDSLMSLELRNRIEASLGLKLSAALLFTYTHTASLAEHLLERL---------
>tr|A0A060ZMX1|A0A060ZMX1_9ACTN Beta-ketoacyl synthase OS=Streptomyces iranensis GN=SIRAN1402 PE=4 SV=1
------------------RSVLDSWRYHVTWNRVPDPAS-VALTGTWLLAVPAGGLVDAVRGLETHGATVVTVEVA-EA-------------DRAAVAAR
LAEA-TAGGTPAGVLSLLGLPDAPHP-----AHAGVPMGLALTLALVQALGDTGVDAPLWLATRGGVSVGGDALDSPAQAAVWGLGRVAALEHPQRWGGM
VDLPDTVDG---RVTTRLCGALAGRDEEDQLALRPSGVFVRRLVRAAEHR---GSGPAWTPEGTVLLTGGTGGVGAQIARRLAQAGAEHLVLTSRRGPEA
PG------ADKLKAELTELGAKVTVAACDVADRAALEALVRRVEAE-GPPIRSVLHIAGAGVLVPLADTDLAEFADTAEAKVAGAANLDALFDRDTLDSF
VLFSSISAVWGSGEHGAYAAANAYLDGLAEHRR-ARGLTATSVVWGIWSPGGMAAN-LAEEQLRGRGIPFMSPRLAIDAFWQVMERDETVVVADVDWERF
VPVF------------------TSAR----PSPLIGQVPDV-ARILAADA----------DTRADATGESSSLRDRLTEL----APADRRAAVLSLVGSQ
IATVLGYEAVDATRAFRELGFDSLSAVDLRNRLGTATGLRFPVTVVFDYPSAEELAGHIGAELFPD------
>tr|M3AT83|M3AT83_STRMB Beta-ketoacyl synthase (Fragment) OS=Streptomyces mobaraensis NBRC 13819 = DSM 40847 GN=H340_29696 PE=4 SV=1
------------------QSVVDSWRYRVDWQPISLSEPTAPGAGPWLIVAPS-QWVRACLALEEAGVPAVLVAGP-RP-------------GRSDLAEL
LRSCRG---APAGVLSLLALAERPA---------------EASLALLQALLDAGFDAPLWCATRGAVSCGEDPVVSPEQAAVWGLGRVAALEHPEVWGGL
VDLPAAPEG---REVGPLPAVLCGDAGEDQVALRPAGVLGRRLVPDAASAG--GTGEGWRPDGAVLVTGGVGRLADHVVRWLAARGAEHVVLLDSDGAGG
RR------EAELAVEVAEYGSRLTVVRTP---------------EE-AARVRTVVHTSLPGVPAPLADVTPDDLTSAVS----AAVALGEPAGA-PVETV
LFFSSLAATLGSREHGAHAAANACLDALAQQHR-PDGPRMVSVGWGIWDLDGDLAL-RQTGLSRRQGLPPLEPRLALGALHTLLDGGGGHVVADVEWERF
APLF------------------TLSR----PTRLLDGVPAA-RRVLEAGP----------EAG--DGADVAELRRELAAL----PARERVGALLKTVRAQ
VAAVLRYQDVDPERAFKDLGFDSLVVVELRNRLRAATGLRLPATLVYDYPTPRALAEHLLERILPD------
>tr|A0A0N0YHB5|A0A0N0YHB5_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. NRRL S-4 GN=ADK82_24125 PE=4 SV=1
------------------LSTVDDWRYEVAWRPMPEAA-TSSLSGHWLVIVPE-GLVLACLSLAAHGARTHSVDAG-AL-------------HRDLF---
--ADHLP--GIEGVLSLLTLDRVRHA-----DHPDVPRGYAATVALLQALGEAGVPAPLWCATRGAVQVGPDVPDGAEQAMAWGMGRVAALEHPDRWGGL
IDLPATLDA---RTGAMLSGALGGAGDEDQLAIRPSGTFVRRLNRARLGAA--TGSRTWDLAGTTLITGGTGALGGHVARRLAGDGAEHLLLVSRRGPDA
PG------ATALRDELTALGARVTVAACDAGDRAALADLLAAVPAE---PLTSVVHTAAALDDGLLDTLTPDQLGRALHAKARAAQNLDELTRD-SLSAF
VLFSSFGGIVGTPGQGNYAPGNAFLDALAQQRR-AQGLVATSIAWGAWGGGGMAEG-AFGDVLNRHGLREMDPEAAAGAMRQAVEHDATCLIADIDWERF
FVAF------------------TATR----PSPLLADVPEV-RRIAQEGN----------GSAG-GAEEPSALAQRLAGL----DDADQDAVLLEAVREQ
VAAVLGFEAVNAKRAFREVGFDSVTAVELRNRIGARTGLRLPVTLAFDYPTPVRLAAFLREQLVPD------
>tr|A0A0F5A286|A0A0F5A286_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. MUSC164 GN=VT50_34800 PE=4 SV=1
------------------QAALDTWRYRIGWQPLDGQRPL-TLPARLLVAVPT-EAAQAITGLTALGVEVAPVGAD-DT-------------DRTRLAAR
INEALDTGA-PGGVVSLLGLDEAPHP-----EHPDVPTGLATTLDLVRALGEAGVEAPLWCVTRGAVSASRDRPEAPAQALVWGLGGAVALEHPQRWGGL
VDLPETLDE---GALRALARVLTGQDGEDQLAIRASGVLARRLRRAGTTR----SGERWQPRGTVLITGGTGGVGAQIARGLADEGAEHVVLVSRRGPRA
PG------AAELEAELAGRGARVTVAACDVADREALARLLHQITQD-GAPLTAVVHTAGALDDATVDALTPERIEAVLRPKVAGARHLHELTRELDLDAF
VLISSIAGTVGAAGQGNYAAASAYLDALAQLRR-ADGLPATSVAWSAWAGGGMIDGEVA-DQLRRRGAPPIDGARALELLRQTVAQGDGFVAADIDWGRF
APAL------------------SATR----PLPLLADLPEA-GATGQDPA----------GAERGA----AALRTRLAGL----GPADRHTALVELVSEQ
AAAALGYGAVETGRAFKELGFDSLTAVDLRNRLNAATGLRLPVTLVFDYPTADDLAVLLRDELLPS------
>tr|A0A0M8W0E0|A0A0M8W0E0_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. NRRL WC-3618 GN=ADL01_17985 PE=4 SV=1
------------------QQQVDALRYQITWKPLPGGS-GPALQGAWALVVPD-GWCAAAEAMAAAGTDVRRVD-E-AA-------------DRTEMTKL
LRDL-----PLAGVLSLLALDERSYA-----QSASFTRGMAATLALTQAVVDAEVGGRLWIATCGAVSVGAESVRGVAQSQAWGFGRVVGLEHPEVWGGL
IDLPEATGA---VPASARAHLTTEDFTEDQLAVRPSGALVRRLVRAPRR-P--APAGQWQPRGTVLITGGTGALGAHVARWCAGGGARHLVLTSRRGPDA
PR------AAELRAELEELGAEVTIAACDVADRDALAGLLAEIP----APLSAVVHAAGLGQDRMIDETGPADFAEIVTAKTAGAAHLDELLGG-PLDAF
VLFSSIAGVWGSGGQAAYAAANAFLDGLAERRR-AQGRAVTSVAWGPWAGSGMAGDD-AAAHLRKRGLPVMRPESAVAALRHALGVRDALTVADVDWERF
APAF------------------TVRR----PSPLLDDLPEA-RRALDAAS----------GVSGATDDAAAALRERLAAA----SADERERTVLKLVREE
VAAVLGHEAVREDRAFKDFGFDSLTAVELRTRLNAATGLSLPSTLVFDHPTPGELSRQLLAELLPD------
>tr|A0A0M9ZUY1|A0A0M9ZUY1_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. NRRL WC-3618 GN=ADL01_17495 PE=4 SV=1
------------------TSTLDRWNYRESWTPLTEAA-AGKLTGDWLVVVPE-GWSAAVALLAEHDARAVTVA-H-AT-------------GRDALGAA
LRAA-----AFSGALSLLSAADD--H-----DSDAVPPEVALTLALIQALGDAGVDAPLWCATRDAVAVGHDAHIAPGRTALWGLGRVAALEYPERWGGL
VDLPDAADT---AAVT------GAWAGEDQVAVRGSGAFGRRIVRAAAPLE-GDKAGEWTPRGTVLVTGGTGALGRHVARWLAHEGAGHLVLTSRSGPDA
PG------ALELRTELEELGVRVTVAACDAADREALARLLDEIGNGGGDPLTAVFHAAGVLDDGVLDAMTPERLATVFRAKVETARNLDELTAG-DLSAF
VLFSSFAGVAGGAGQGSYAAANAFLDGLARARR-ARGLTATSVAWGPWAGSGMAAEG-AAERLRGGAIPPLEPDRAIAALKRLLTQDRTAMVADVDWQQY
APAF------------------TAVR----PSRLYTELPEV-ERLSAAAV----------ADGGGAAGQGPDLVAKLVSL----QRAEQERLLLDLVCEQ
VAAVLGYAAVEPTRAFRELGFDSLTAVELRNRVNALTGLVLPATVVFDHPTPTALADCLRTELAPD------
>tr|A0A0M8W4C5|A0A0M8W4C5_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. NRRL WC-3618 GN=ADL01_15110 PE=4 SV=1
------------------SAELDALRYRVSWKPLGQAP-TARLDGTWLLVVPD-RWTDAVEVLGGRGADVRTVA-G-EI-------------DREEFAER
LRKE-------AGVLSLLAVDE---A-----VRGGVSRGLATTVTLVQALHAADLGAPLWLAGRSAVTVGGDPAPRYVQAALWGLGRVVAVEYPALWGGL
VDLPGTPDG---RALD------GAWAEEDKLAVRGSGVFARRLVRDTSRGA-ADGGDTWTPHGTALITGGTGAVGGHVARWLAAHGARHLVLTSRRGPDA
PG------AAELLAELQELGAQVTLTSCDAADRDALAGVLDAIP----DPLTAVFHTAGVLDDGVLDGMNAERLATVFRAKVESARHLDELTRD-DLSAF
VLFSSFAGLSGGAGQGSYAAANACLDALAEHRR-AQGLNATSVAWGAWAGGGMAADG-AAERLRGGAMPPMESRAALAALRRALGHEQPTVIADVDWEQY
LSGG------------------PGVA----SDPLFGDLAET-RALRDRAA----------RT--NGEAEGPDLARRLAEL----SGPERERFLEDLVRTH
AADVLGYEQVEPGRAFRELGFDSLTAVELRNALGAATGLPLPTTLVFDHPTPAALAAHLKAELATD------
>tr|V6U896|V6U896_9ACTN AMP-dependent synthetase and ligase OS=Streptomyces sp. HCCB10043 GN=P376_4933 PE=4 SV=1
------------------KSMHNRLRYRVAWAPLPPVAD-GAPTGSWLVVVPP-TRVVGMVMLEGLGMRTRIVEANSA-----------------DYVDT
MRRATAE--EFTGVLSLVALDPRKRP-----GFPVLTEGTAATLALVRAHGEIAAGPPLWCVTSGAVSIGPDPLRAPQQAVIWGLGHAAALEHPDRWGGL
VDLPEVIDA---RTGPALFGVLNGPSGEDQIAVRSAGVFGRRLSESPLRTE-P-TRRDWRPRGTVLVTGGTTGLGRHAARWLAEAGAEHLLLTVDGDPQA
TH------VHDCVAELTELGVGVTVSAADISSRAGVAELLAESPSR---ALTAVVHAADLARTMPVGDIDADALREVLSVKADSALYLDELLGD-PLDSF
VVFSSAAGVWGGGGQGVAGAVNAFLDALVEQRR-ARGLSSTSLAWGVIEGLGVAADPAVQQLLRRRGVTPMASEVAVGALSAAIQSDDGVAVADIDWSTF
VPAF------------------TSSR----PSPLLSDLPEV-RRVTEAAG----------SA-P-QAETDAGLANQLAGA----NEAEQTRILLKLVREQ
AAAALGQEQVKPRQAFQEMGFDSLAAVTLRNALAAAVGASLPATAIFDYPTPAALVEYLRDELVAD------
>tr|A0A0J7YRX8|A0A0J7YRX8_STRVR Uncharacterized protein (Fragment) OS=Streptomyces viridochromogenes GN=ACM01_46185 PE=4 SV=1
------------------RAEVTRLRYRVGWTPVPHAST-GTPGGALLVLAPP-GGVARIMALDGQGRRSRLLAAHGE-----------------DPADA
LGEVLGD--EFTGVLSLLALDRRTRP-----ESPALTEGTAATLALLRALGAGTVGLPVWSVTSGAVSVGPDRLRAPEQAVVWGLGRAVALEHPDRWGGL
VDLPETLDD---RTVRALLGVLGGASGEDQVAVRSAGVFARRLLESPLRNE-P-RQADWQPRGTVLVTGGTESLGRHAARRLALAGAEHLLLTVDGDPDA
SD------VQDLVAELTGLGVGVSVSTADISNRAGVAELLADPAGR---ALTAVVHTVDSAGMLPVASTDVDELGKALRVKADAALYLDELLGD-PLDAF
VVFSSAAGVWGGGGQGVTGAVNAFLDTLVEDRR-QRGLAATSVAWGVVEGIGVAADPAVQEQLRRRGVLPISTDLAMTSLAAALRSDDGVAVADIDWSAF
VPAF------------------TSVR----PSPLLGDLPEV-RRLAEAAV----------EAAA-EAEAGSALVQSLAGL----SEADQKRALMKLVRER
AAAALGHEEVKPRQAFQEMGFDSLSSVTLRNTLAAAIGESLPATLVFDCPSPAALVDFLHETLAGT------
>tr|Q7X4R5|Q7X4R5_STRHY ShnC (Fragment) OS=Streptomyces hygroscopicus PE=4 SV=1
------------------RSSAERLRYAVTWRPLDREVS-RVPAGRWLAVLPP-GVTAELIELGAQGLDVVPFTVPSAF-------------TRTGLTAR
L-SDIAE--QPAGVLSLLALDGEQ----------DVIDTVARTLALVQALGDAGVNGPLWCLTRGAVNTGIDTAGEPGDAAIWGLGRAAALEHPDRWGGL
IDLPATADA---HTAQYLVGALNGTAG-DQLAVRRPGLYSRRLVRKPASQT-P-ADGGWRPHGTVLVTGGAEALGIHASLWLARSGARRLIVTTTAQAPA
DA------VTELQGKLAAAGVETTVVSCADADRETLARLIAETPRE---PLTAVVHAADAPWTSAVADTGHADLTEVFAGKVDTAVWLDELFTA-PLDAF
VVFSSIAGIWGGGGQGVSGAAGAVLDALVDRRR-GRGLAATSIAWGALDGIGLGMDEAAAAQLRRRGVLPMAHQVAVTAFEQAAEAREKATVADMDWEAF
IPAF------------------TSAR----VSPLFADLPEA-AAALRSSQ----------PD-A-NGDITSSLVDSLRDV----PQAEQNRLLLRLVCGQ
AATVLGHESIGPLQSFQEVGFDSLGAVNLRNSLHVATGLRLPATLVFDYPTPDAVVGFLRSELLTE------
>tr|A0A0M8VYX3|A0A0M8VYX3_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. NRRL WC-3618 GN=ADL01_17460 PE=4 SV=1
------------------RSTLDSWRYQVAWQPLA-GALPTRLTGRWLVVRPE-NWATGVRALAAAGADVVELTTG-EL-------------TREALTER
LREAAA---GLAGVVSLLSLDESEQD-----THGVVSAGLVGTVALVQALGDAGTSARLWAVTRGAVATDRDQPARPAQAQVWGLGRVVALEFPDRWGGL
VDLPENPDG---RAASQLP---GAVGDEDQLAVRQAGVLVRRFVRAPVGAG---ETREWAPRGTALITGGTGAIGGHVARWLAREGAEHLVLTSRRGLDA
PG------AVELQAELEELGAKVTIAACDVADRDAVAGLLGRLTED-GHILRSVFHAAGVGQGQPLDAMTAADVAEVLEAKVAGAAHLDALLDSAGLDAF
VLFSSNAGVWGSGSQGAYAAANAHLDALAEQRR-ARGLTATSVAWGLWAGSGMAGE-DGEEQFRRRGLRPMAPNLAVAALAQAVAYDETFAVADLDWERF
AAAF------------------TSAR----TSPFIGDLPEV-RRYVESVA----------VEPAGGDDAADELRGRLVPL----TEPEREVILLDIVRSH
AAAVLGYESIDAHLAFRELGFDSLTAVEVRNRLNKATGLRLPATLVFDHPTSVALAQYLRTELLQD------
>tr|S3ZC67|S3ZC67_9ACTN Putative Oleandomycin polyketide synthase, modules 5 and 6 OS=Streptomyces aurantiacus JA 4570 GN=STRAU_6729 PE=4 SV=1
------------------RSTLDSWRYQVTWQPLA-GTLPTGLTGRWLVVLPE-SWAAGVRALAAAGADVAELPSA-ES-------------TREALAGR
LREAAT---GLAGVVSLLGLDESPHD-----AHGVVPAGLVGTVALVQALGDAGIGARLWVLTRGAVATDRDQPARPAQAQLWGLGRVAALECPDRWGGL
VDLPENPER---RAASQLP-----AGDEDQLAVRQAGVLVRRFVRAPLAAG---ETRQWKPRGTALITGGTGAIGGHVARWLAREGAEHLVLTSRRGPDA
PG------AAELQAELEELGAKVTVAACDVADRDAVAGLLGRLTED-GHTLRSVFHAAGVGQGRPLDGTTTADIADVLKAKVAGAEHLDALLDASGLDAF
VLFSSNAGVWGSGSQGAYAAANAHLDALAEQRR-ARGLTATSVAWGLWAGGGMAGD-DGEEQFRRRGLRPMAPGLAVAALAQAVAYDETFAVADLDWERF
APAF------------------TSAR----TSPFIGDLPEV-RGYLESVA----------AEPAGGDDAAAQLRRRLAPL----TEPEREVILLDIVRSH
AAAVLGYESIDAHLAFRELGFDSLTAVEVRNRLNKTTGLRLPATLVFDHPTSVALAQYLRTELLQD------
>tr|A0A0F5A2M7|A0A0F5A2M7_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. MUSC164 GN=VT50_36375 PE=4 SV=1
------------------RSTVNDWRYRVVWKPIVESGAGPKLTGTWLAVVPA-GWVHDALVLARSGATVVPLASA-GA-------------DRVTLAED
IRAAVRHAASVAGVLSFLALDE---A-----VHQAAPAGAAATLTLVHALSDLAMDLPLWLMTRGAVAVGRDALPSPLQSMVWGLGRVIGLEHPQWWGGL
IDLPDVLDD---RAARRWLAAL-SPADEDQVAIRTSGAFVRRLVRARTGEPSGALGGAWRPRGTVLITGGTGALGGHVARWLAEAGAAHLLLVSRRGPAA
PG------AAGLVAELEAAGTSVTVAACDVADREAVRTLLATLP----EPLSTIVHTAGSGGDLPVAETRLESFADVLDAKVTGARCLHELTRE-ELDAF
VLFSSAAATWGSGGQGSYAAANAYLDALAEHRR-ALGLAGTSIAWGAWADAGMAVVD-AEEMVRRRGLRSMPPELAVVALQQAWDADEASTVADVDWERF
VPGF------------------TAAR----PRPLLMDLPEA-ARAIEATR----------P----VGENASAWLTQLTEA----SVEERERSLVELVRTH
VAAVLNYKDIAANRALKDLGFDSLTAVELRNRLNAVTGLALPTTVVFDHPTPAALVAHLRVQLFGQ------
>tr|A0A0F5A858|A0A0F5A858_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. MUSC164 GN=VT50_27180 PE=4 SV=1
------------------RSAADRHLYNVVWKPRPQSGPSPAPSGTWLTVVPA-SRITAVAELTRRGVRVVRLDAA-DT-------------DPAALADR
LAAS-SADGPVAGVLSLLALDERPHP-----EHPAVPVGLALTGALAEALRGDDVPARLWCATRGAVSTGGDRLESATQAQVWGYGRVVALEQPERWGGL
VDLPESVDE---RALDRLAAVLAGPDDEDQVAIRATGVFVRRLVPAPRTAA-TAAAEPWTPHGTVLVTGGTGALGRHVARWLADHGAERLVLLSRRGPDA
PG------AAEIVAELSGTGTAVTVEACDVADRHALAALVEKLAAN-GSPVRAVVHSAGISQE-PGTGTELPEFARIVAAKTAGAVHLDALFGEDPLDAF
VLFSSIAGVWGSGGQGAYAAGNAFLDALAEARR-ARGLPATSVAWGPWADGGMAAEGDAEEQLRRRGLPPMAPESNMVAFQRVLSREETATVADVDWERF
APAF------------------TAAR----PRPLIDDLPQV-AKALRGDD----------SEPTAAADGAPALRDRLAGL----SAAEREDAVLELVRTH
VASALGHAEVEAGRAFNELGFDSLTAVELRTRLGAATGLKLPASLVYDYPTPAALAEHLLAELVPD------
>tr|T2RMS4|T2RMS4_SACER Uncharacterized protein OS=Saccharopolyspora erythraea D GN=N599_36110 PE=4 SV=1
------------------RSVLDSWRYRVAWRPVPEPPA-AGLRGTWFVVAPS-DWIDQCASLEQRGAQVARIDAA-EA-------------DATSLSAE
LAAE-----ERGGILSLLALTEGTHP-----LHPSAPLGLTANLALVKAVADAAAGTPLWLLTSGAVSTGDDPVRDLGQAAVWGLARTVALELPRQWGGV
VDLPADAGE---HATDRLCAVL-AAGAEDQVAIREPGVMGRRLVRAPLAET--AVTREWRTSGTALVTDGTGPMGARVAAWLVEQGAEHLVLTVDDDTDA
DH----------AALEAELGVPVTVAACDVADRDALASVLDGIPAD---PLTAVVHTAGVLGAGALLEAGPAEFAATARAKVRGALNLHELTLD-DLAAF
VLFSSVAGVWGGSEQGAYGAANAVLDALADRRR-ALGRPVTSIAWGPWADAGMGAAEARREQLRRRGVLPMPSERTLGALRDALLHGDTATVVDVDWERF
APAF------------------NAAR----PSALLAELPEV-RRVLDAAN----------AEAA---EGGQEFAALLAGL----PQDERELRLVELVRRE
VAAVLGHEALPAGRAFTELGFDSLAAVGLRNRLGAATGAKLTASAVFDHPTPERLAGHLLRQLAPP------
>tr|M3D1X7|M3D1X7_9ACTN Modular polyketide synthase OS=Streptomyces gancidicus BKS 13-15 GN=H114_04117 PE=4 SV=1
------------------RATVDGWRYRVVWQPRELP--AGSLHGTWLLAVPE-TLTLRTRALTKAGADVVRLVPD-NA-------------DRVVLAER
LAALTSG--PPAGVLSLLALDGAPDK-----RSSGVSRGLLASMALSQALADAGLVTPLWAVTRGAVVAG-TTEPDAGQAAVWGLLRVAGLDDPERAGGL
VDLPAGDDA---HGLLPHLTVLGERGRETEFAVR-GGVYVRRMVRSPRDEGPTTARPGWKPRGTVLVTGGTGALGAHVARDLAREGAEHLLLTSRRGPDA
PG------AEALREELTALGCRVTVAACDVADRAALAALLDGVPEE---PLTAVVHTAGVVDRAPFTDIDADEAVDLVHAKVVGAQHLHELLAG-PLDAF
VLFSSGAGVWGNGGQAPYAAANAHLDALAERRR-AAGLPATSIAWGAWAGGGMVDA-EVGEQLLRRGVPAMEPGLAVRALREAVADGDTTVVADIRWDRF
VPAY------------------CAHG----HRPLIDDVPEV-RDLLARRH----------EEEAQDTTAADGLRGELAAL----PPAKRRRRLVDLVRTH
VATVLGSDGVRTGKAFRDMGFDSLTAVELRNRLGSALGTRLPATIVFDHPTPNALAAHLDDELFPE------
>tr|J1RV89|J1RV89_9ACTN Modular polyketide synthase OS=Streptomyces auratus AGR0001 GN=SU9_33893 PE=4 SV=1
------------------RSTVDGWRYRIVWRPQPEP--EGELEGSWLIVVPA-DLVQATSGLGDRA---RIMVSA-TA-------------DRAELLAQ
LAALAAA--EPLHVLSLLALDDRDAG-----GHRGVPGSLLSTLALTQALAETEVKARLWAVTQGAVSTDASDPRHPGQAAIWGLARVFGLDHHERWGGL
VDLPGTLDE---HALRRFLSLL-DGGSQDEYAIRPSGVHVRRMVRAPLDPS--AVVEPWQPRGTVLITGGTGALGAHVARALAAGGAEHLVLAGRRGPDA
PG------SAELSAELTALGARVTVAACDVTDRAAVAKLLDSFTDE---PLTAVVHTAGVVGEAPLDETSLDDAMAAVHAKVSGAWHLDELLAD-PLDAF
VLFSSGAGVWGNGGQGPYAAANAALDALAEWRR-AQGRPATSLAWGAWAGGGMVDE-AVAEQLRRRGVPAMDPGLAVHALREAVDHGETTVVADIRWDRF
LPAY------------------TVSG----PRPLLDELPDV-RQLLAGQE----------EQAD-AGEKGSDLPDRLAAL----PEPKRKRMLLDLVRTH
ASAVLGHDAVRPARAFRELGFDSLTGVELRNRLNAATALTLPATLVFDHPTPTALAEYLRDALLPP------
>tr|A0A086GQY1|A0A086GQY1_STRSC Modular polyketide synthase OS=Streptomyces scabiei GN=IQ62_28880 PE=4 SV=1
------------------RSTLDDWRYRVAWRPYTAP--EGALDGEWLLVVPE-AVTARTRALEESGAGVVPVVPE-QT-------------DRAVLAEL
LDAAAAG--PPAGVLSLLALDDEPDK-----RSAGVSSGLLASMALSQALTDTALSTGLWTLTRGAVAVDDGDEPNSGQAAVWGLLRVAALDDPERSGGL
VDLPADGSA---E-LLSHLPAL---GGDSEFALRPTGVRVRRMVRSPLVGAGSDVPPVWRPRGTVLVTGGTGALGAHVARELACEGAEHLVLTSRRGPDA
PG------AAELERELTGLGCRVTVAACDVADRDALAALLESIPAD---PLTAVVHTAGAVDQAPLTRVDVEEAVDLMDAKVVGAENLHELLAG-PLDAF
VLFSSGAGVWGNGGQAPYAAANAHLDALAERRR-AGGLPATSIAWGAWAGGGMVDA-EVGEQLLRRGVPAMEPRLAVRALRESVAAGDTAVVADIRWDRF
VPAY------------------CAHG----HRPLIDEIPDV-EAMLTTRQ----------AEDADRDGAMTALRGELAAL----PEAKRRRRLTDLIRTH
VTAVLGADGVKPGRAFRDMGFDSLTAVELRNRLGAALGTGLSVTLVFDHPTPNALADHLGAELFPA------
>tr|X8EZC8|X8EZC8_MYCUL Polysaccharide biosynthesis family protein OS=Mycobacterium ulcerans str. Harvey GN=I551_8209 PE=4 SV=1
------------------QSELDSWRYQVTWLSSPTTPSSTTLSGIWLLIVPS-EPVIGCAALEAHGALVTIIFEP-DF-------------NRSLMGAS
LKDIG----HISGVISFLGIHGSEF----------SDSGAVKTLNLVQAMGDVHLDVPLWCLTQGAVSISADLIRCSSAALVWGLGRVVALEHPGSWGGL
VDLPESPDD---AAWERLCALLAQPTDEDQFAIRPSGVFLRRLIHAPATTT-SKSSTAWAPRGTVLITGGTGALGAHVARWLAHKYEVDLLLTSRRGMAA
DG------ATELVDDLRTAGASVTVHACDVTDRTSVEAAIAGK------SLDAVFHLAGRHQPTLLTELEDESFSDELAPKVHGAQVLSDITSN-TLSAF
VMFSSVAGIWGGKSQGAYAAANAFLDSLAEKRR-TLGLPATSVAWGLWAGGGMGDRP-SASGLNLIGLKSMSADLAVQALSDAIDRPQATTVASVNWDRF
YPTF------------------ALAR----PRPFLHEITEV-MAYRESMR----------SSSA---STATLLTSKLAGL----TATEQRAVTRKLVLDQ
AASVLGYESLDTHESFKDLGFDSLTALELRDHLQTATGLNLSSTLIFDHPTPHAVAEHLLEQIPGI------
>tr|S3ZQL1|S3ZQL1_9ACTN Putative Oleandomycin polyketide synthase, modules 5 and 6 OS=Streptomyces aurantiacus JA 4570 GN=STRAU_6263 PE=4 SV=1
------------------RAVIDSWRYRVAWQPLPAGRLPARLSGRWLVVVPD-SWVTGAAALTGAGAEAVRWGTE-ET-------------TRDGLAAR
LREAASGGSPLVGVVSLLGLDETPLD-----EHTAVPAGLAATVALVQALGDIGSDARLWALTQGAVSTGRDRLDHPVQAHLWGLGRTVALEHPDRWGGL
VDVPRSYDT---RAGARLAAILAGPGTEDQLAVRGSGVFVRRLLRGEATGAGLTRHTRWTPRGTVLVTGGTGALGGHVARWLAREGAEHLVLTSRRGPDA
PG------AAELRAELEEHGARVTVAACDAADRQALARVLDGIP----APLTAVVHTAGILDDGVVDGLTPERFDGVLRPKSPAATTLHELTRD-DLDAF
VLYSSASGALGSAGQANYAAANAYLDALAEQRR-ADGLPATSIAWGTWDGAGLADTAVRSDRARRDGMPPMPPEPAVAALRDAVERGDAHVVAAVDWDTF
LPGF------------------VAAR----PNPLFDALPEV-RRRTADSA----------DGTPGATVTGPEWIRRLAPL----PPAERDAALVTFVRSQ
AAAVLGHDAVDPARAFRELGFDSLTAVELRNRVQAATGLRLPASLVFDYPNSAVLAAHLAEEAFGA------
>tr|S3ZNP4|S3ZNP4_9ACTN Putative Oleandomycin polyketide synthase, modules 5 and 6 OS=Streptomyces aurantiacus JA 4570 GN=STRAU_6973 PE=4 SV=1
------------------RSTLDSWRYRVTWKPLASGALPASLTGRWLVVVPE-DWLAGVTALTQAGAMVTEVSDA-EL-------------TREALTGR
LRAYADAPGDPAGVVSLLALAEHPHP-----SHPVLPTGLAATLALVQALGDTGIGARLWAVSCGAVSTGRDRLGGPEQAQLWGLGRVVALEHPDRWGGL
VDLPPTPDN---RAATRLATALGGTGFEDQVAVRGSGLFVRRLAHAPLDAR---PAPAWTPRGTALITGGTGALGAHVARWLAREGAEHLVLTSRRGLDA
PG------AAELKAELAELGAEVTIAACDVADRDAVAGLLDELAAH-GHRIRSVFHAAGVSPALALADTAPADLAEALDAKAAGAAHLDALLDD-ELDAF
VLFSSIAAVWGSGGQAGYAAANAFLDAVAERRR-ARGLTATSVAWGAWGGSGMAATAEAEEHLRRRGVALLAPDLAVGALAQALAHDETCTVADVDWERF
APTF------------------TAAR----PSAFLGGLPEL-RPQTRQAT----------AGAAEAR-RATASRSRSGPP----GSPGSRRRSG-----S
ASSSTSYRPRPSAPPAPSASWASTP----SPRWSCATASPPPPRSRCPRPW---------------------
>tr|A0A0C1QE45|A0A0C1QE45_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces pluripotens GN=LK07_27715 PE=4 SV=1
------------------AATTDGWRYSVGWRPAEA-AE-PTLSGDWLVVSPD-G-AEDCAVLTRAGAEARVL-------------------GPDALPAA
LAGA-----AVRGVVSLLGLAEGPHP-----EQPAVPAAVAATLELVRALADTDTGAVLWLVTTGAVATTPDWLPHPEQAMLWGLGRTLALEHPKLFGGI
VDLPQDPTL---G-LDRLPAL--LAGTEDQVAVRATGVLVPRLAHAPLRGR--TPARRWQPTGTVLVTDGLGPMGLPAARWLAGNGAQALVLTTDDPA--
------------ATAPDDLGVPVTLSTCDPADETALAELLAGIPAD---PLTAVVHAAGTLRSGPLAGTDLSEVAATIDTKVRGAANLDRLT---ELDAF
VLFSSIAGTWGGSEQGAFAAANAYLDALAQHRH-ARGLPATAIAWGPWQGAGLGDTERRREQLRRRGVLALAPQQALAAMADAVRHADTTTVADVDWAVF
APAF------------------TAAR----PSPLLGELPEV-RDSLAEVT----------DEPA---G--SGTATRLGSL----PEADQQRELIELVRRE
VAAVLGHETLPTGRPFTDLGFDSLAAVNLRNRLGAATGVRLAATAVFDHPTPAGLADHLRRQLVVP------
>tr|A0A0C1SIQ3|A0A0C1SIQ3_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. RSD-27 GN=PL81_26115 PE=4 SV=1
------------------QSTVDGWRYRVIWKPQADAA-SPRLSGSWLVAVPE-A-AAGVLTLADRGAEVRTVAPD-AA-------------GRDALTAA
LKAATGA--APAGVLSLLALGD--------------DGAFAAGLALSQALGDAEVAAPLWCVTRGAVVAGRDRIADPEQALIWGLGRVASMEQGGRWGGL
IDLPGPVDD---RALERLAGVLAGDAAEDQVAVRSSGLFVRRLVRAGLSET--PAVREWRPAGTTLVTGGTGALGAHVARWLASSGAEHLILTSRRGADA
PG------AAELRDELTALGAEVTIAACDVSDRDALAALLAAIPAD---PLTAVIHAAAVVDDGVIEALTPEQVERVLRVKVDATRHLHELTRD-DLSAF
VLFSSFAATFGAPGQGNQAPGNAFLDAFAEYRR-AAGLPATSLAWGPWGSGDGDGS-AAGDRMRRHGIIAMAPERTLASLRHALDRDETTTLVDMDWKRF
TLAF------------------TADR----PRPLLLELPEA-RRVIESAE----------REST-DLAGGVPLSTQLAGL----PDVEQERLLLDLVRTA
VAAVLGHTAVEAGRAFKELGFDSLTSVELRNRLGAVSGLKLPASLVFDHPTPAAVAAYLRAGIVPD------
>tr|A0A099D0D6|A0A099D0D6_9ACTN Uncharacterized protein (Fragment) OS=Actinopolyspora erythraea GN=IL38_24395 PE=4 SV=1
-------------------GDEDNWRYQVVWRDSEWQS--TSLAGRVLLVTGPG-LSNSVRGLEQSGATVLVC-----E-------------SRHVIGAA
LEEAD----ALSTVVALLGGEGETV------------DASLDALALVRALGVAGIEAPLWVLTRNAVQVTD--EVDPAQAMVGGLGRVVGVEQPSRWGGL
VDLIDV-DA---ASVRALAAVLADPRGEEQIAIRPDGIKVARFVPAPARAA----RTRWSPRGTVLVTGGTGGIGAHVARWLARSGAEHLVLLGRRGADA
PG------AAELRDELIALGTGVTIAACDVADRERLEEVLAAERAE-G-SVNAVLHAAGISRAAPVEEITETEFAEVAEAKVRGTVNLDELCP--DLDAF
VLFSSNAGVWGSPGLACYAAANAFLDGFARRRR-SEGARVSAIAWGLWAGQNMAGD-EGGEYLRGQGLRAMEPERAIEELHVTLDHGQASSVVDMDRERF
VELF------------------TAAR----RRPLFDEITGA-RGEARQS------------------EEDPKLEQRLAAL----SEFERREHVARLVHTE
VAAVLGHTMIDRDRAFRDLGFDSMTAVDLRNRLAAVTGVREAATVVFDHPNITRLAEHYLEQLVGG------
>tr|D9WB06|D9WB06_9ACTN Oleandomycin polyketide synthase, modules 5 and 6 OS=Streptomyces himastatinicus ATCC 53653 GN=SSOG_00512 PE=4 SV=1
------------------RSAAGAWCYRADWTRLREP--ATPLTGRWLAVVPA-EWA-A--VLDALGPDVVRISTE-DT-------------DREQLAAR
LAHAGNS--EFTGVLSLLGLAERPHS-----GFTSVPSGLSATLALVQALGDARLRAPLWCVTRGAVSAARDRVSHPVQGALWGFGRVVALEQPGLWGGL
VDLPETLDQ---RAAARLAGVLAGLDGEDQVAVRASGAFGRRLFHAEPASA--RPERPWRTRGTVLITGGTGGLGPYLARWAIERGAGHVVLAGRRGPDA
PG------ATALRAELEGLGARVTVVACDAADRDALSAVLSAIPAE-FPPLSAVIHAAGVTDGDEAASLTPDRLDALMRPKLTAALNLHELTTD-RLDAF
VLFSSGASAWGSGGQPGYAAGNAYLDALAEHRR-ARGLTATSIAWGAWGEAGMATDPHLVERLAKRGVLPMEPPKAIAALQRVLDDDRTTTVSAMDWAAF
APSF------------------TVSR----RSPLLSGLPEA-REPAPADT----------AGEADTADGTPSLPHRLAEL----PDAERRRVLLDAVRAE
VAAALGHDAVPADRAFRDLGFDSVSAVELRNRLKAVTGLPLPAALVFDHPNPTALAGHIGAELFPG------
>tr|A0A0F5A528|A0A0F5A528_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. MUSC164 GN=VT50_29325 PE=4 SV=1
------------------RSAIDSWRHRVVWKQLPDSA-TPTLSGTWLLLVPS-GAVHATIALDAHGAAHEVLDGT-DA-------------RPDALAPK
LSQLSLPDGTPEGILSLLALDQAPHP-----EHPAVPVGLAATAAVVQALSRTALTAPLWCVTQGAVAATADPLPHPHQAQIWGMGRVAALEHPHLWGGL
IDLPADVDA---RTPARIAAVLAPGQPEDQVAIR-ATPLARRLERATCQDT---APTAWRPTGTTLITGGTGGLGAHVARWLARRGAPHIHLISRSGPDA
PG------AAQLTEDLTALGAAVTISACDVADRAALQHLLDTVPAE---PLTAVVHAAGLAENTPLAELDLPGIEAVLRPKALAATHLHELTEH-DLSAF
VLFSSGAAAWGGSRQPSYAAANAYLDALAEHRR-ARGLPATSIAWAPWSDAGMAADEAVVDYYRRRGMRPLDTDLAIASLQHALDHGDTTTIADIDWERF
PAGF------------------TAQR----PSPLLSDLAAS-ASPGTDAT----------P---DDAALSSSLQRQLATG----TPAQQHQLLLHHIQTH
AAAILGHDAIPPAQPFQELGFDSLTAVEFGHRLSSATGLGLPPTLVFDHPTPKELADYLRERLVEG------
>tr|A0A014MJ18|A0A014MJ18_9ACTN Beta-ketoacyl synthase (Fragment) OS=Streptomyces sp. PRh5 GN=Z951_46685 PE=4 SV=1
------------------TSVTDRWRHRIDWSPLPEPPA-VAEPGRWLVLGAT--WTDSVVALGDQAVH----VSA-EA-------------PRAELAER
LRAQP----PADGVLLT-------------------PGTPVDAAAMLQALDDAGLATPTWIATRAAVAVGSDPQPWADQAGVWGLGRVAAWEYPAHWGGL
VDLPEDVDE---AVAARLRSLLTEEKAENQVAIRSTGLYGRRLVRAAPEA----PTRAWTPEGTVLITGGTGGLGAELARWAAGRGADHLILLSRRGPDA
PG------AGELREACEQAGARVTFVAADVADRARMAAVFDE-------PVTSVFHLAASLDDGVLDTLTPDGFATVARAKVRGAQVLDELTRG-GLSAF
VLFSSISGVFGVPGLGAYAAANAMLDALAVSRR-AAGEQALAVAWGAWAGEGLATHVVGDERLRRMGLTAMPAKAALVALEHALNREDTTAVFDADWDRV
-PAH------------------TRDG----LGTLLHELPEA-RRPAAVSR----------P-------DAADLRTLLAGL----DAAQRTAKLRDLVHAE
VADALGHVAVDPRRAFSELGFDSLTSVRLRNRLTELTGLSMPVTVVFDFPTVTELGEHLAGRLGGA------
>tr|A0A0M3U7J4|A0A0M3U7J4_9PSEU Polyketide synthase OS=Pseudonocardia sp. AL041005-10 GN=WY02_28940 PE=4 SV=1
------------------ASDPEGSLYRLEWRRSTSPPVP--PAGPVAVLGDP-ARVHRLTLLRPAPAVLVTVHSS-GT-------------DSAPIR--
-----------------------------------AERCISRTLGQLQAHG--PAQSRLVVATRAAQ-PGPDHEVDPAAAAVWGLVRSAQTENPGRFA-L
VDLDDD--P---ASWELLARAA--TDTRHQFRIRNGVVETPRLVPVAEPVP--TASPALDLAGTVLVTGGTSGLGAVLARHLVARHDRSLLLVSRRGPDA
PG------AAALTAQLRAAGADVTVAACDVADRMAVADVLAEVPAD---PLCAVVHCAAALEDGVVESLDPARIRAALAAKGVGAWNLQALTES-DLAAF
VLFSSVAGTLGTAGQAAYAAANAFLDGLAAGRH-ARGRPATSLCWGYWAEDLSALRDSDLDRLRRQGVGALDTQRGLALFDAALHRPEPVLAARLH----
PPAP------------------TDDR----LASLLTTLSAP-PARTDPPG----------PDEYTATSRGDSPAERLAGL----TESEAEARLLKIVRHH
TAVVLGHAALAPSSSFKELGIDSLTALEVRNGLAHALGTALPATLVFDHPTPAAVSRHLLRTLGPS------
>tr|A0A014KWX1|A0A014KWX1_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. PRh5 GN=Z951_46945 PE=4 SV=1
------------------RSQVDAWRYRTAWSPVSEVA-AAALTGSWLVVVPA-GWVADCVVLATRGAQPVVVD-A-DA-------------DREAVAGR
L------RDDVTGVLSLLALAE---G-----RYAAVPSGLALTLSLLQGIGDAGVGGRVWCVTRGAVATGGERPSSLEQAAVWGLGRVAGLEAPERWGGL
VDLPQTPDG---RALDRLTAVI-GATGEDEVAVRASGVFARRVVRAAVGAE---SGEAWQPSGTVLVTGGTGALGAHVARWLARAGAGHLLLVSRRGPAA
EG------VDKLRAQLAELGARVTVAACDVGDREALAGLLARVP----EPLTAVVHTAGVLDDGVLDGLSVDRFEGVLRAKSEAAWHLHELTRE-ELSAF
VLFSSFSATVGGAGQGNYAAANAFLDALAEHRR-AEGLPATSVAWGPWADGGMATQDAVSGRMERFGLPAMEPELAVTAMARAVNQSDTCIITDIDWPRF
TAGV------------------DGTR----LGLLFGDIAEV-RTARQAAD----------A---QAGTHRPTLATTLAEL----PAAEREPALLDLVRTH
TAAVLGYEGIDAERGFFDMGLDSLTAVELRNRLNAATGLRLRPTALFDYGSPSALAHHLKGELVED------
>tr|V6L2I9|V6L2I9_9ACTN Uncharacterized protein (Fragment) OS=Streptomycetaceae bacterium MP113-05 GN=N566_10455 PE=4 SV=1
------------------RSTLDGWRYRTEWKSVHPA--GEPLAGTWLLVRAD-GALDETAALSDGGADLVEVA----G-------------DVADLGTR
LSEALD---TPTGALCLTAFDEAPLS-----TGGPVPTGLALLTATAAALEALGTDAPLWAATVQAVGTGPDPPCNPAQALVWGAGVVLGLDLPRTWGGL
IDLPATLGP---TGAEQLRVALIGATGEEQLALRPDGLTARRLVRAPADAG----TAPWRPRDTVLITGGTGALGGHLARWAARSGASRVVLVSRRGEAA
AG------MPELRDELFDLGTEAVIAACDLTERDAVAALIEKITVD-GPPLRAVLHAAGTSGREAVADLTTDDMATVLGPKAAGARHLADLVDDEKLDTF
LLFSSGAGIWGNAGRVAYGAANAYLDALAAARS-ASGRPTTSLAWGPWGGGGMVDA-DTGRYLQRLGMRQMDPEQAVQALADSVGRGEGEVVADIDWKTF
APTY------------------TAAR----NRPLITGVADA-RDALTAAD----------DTPG-TEDGEPELVRELGGL----DAAERQRQLLDRLRRE
AAVALGHAEMRADR----------------------------------------------------------
>tr|D9WB07|D9WB07_9ACTN Modular polyketide synthase (Fragment) OS=Streptomyces himastatinicus ATCC 53653 GN=SSOG_00513 PE=4 SV=1
------------------RSTVDSWRHREVWRRRSFPA--GKASGTWLVVTPP-GWISTVAALGPDTVRIEAR--G-DA-------------GRAALAER
LTTAT-GLPSVAGVLSLLAADESA-------DDAGVPAGLVRTAALVQALGDAGLHCPLWCVTRGAVAVNDEHPSGPAQAAVWGLGRVAALEYPDRWGGL
IDLPTELNE---PSAAAFVAVLAGRDGEDQVAVRPSGTYVRRLVPAPAP----RPAAEWEPSGTVLITGGTGALGAHVARALARRGPPHLLLVSRSGPAA
SG------AADLRRELTELGADVTIAACDAADRAGLEAVLADIPA--DRPLTGVVHAAGVLDDGVLDRLTPDRFAAVFRAKVASALLLDELTRDADLSAF
VLFSSVSSVVGNPGQANYAAANASLDALAQRRH-ARGLPATSIAWGGWGGAGMAARP--SGASGGVALARLDPRLAVSALSEAVTEPHPTVVADLSHLAS
QDPP------------------SGLR----RTPLLEELPYA-RRAPRE---------------------GSAPAPRLRDL----PEAERAARALETVRER
AAAVLGHNLVHADKAFRDSGFTSLTAVELRNHLAAETGLALPTGVVFDYPTPRLLAEHLVAGLGGE------
>tr|J1ZM11|J1ZM11_9ACTN Acyl transferase OS=Streptomyces auratus AGR0001 GN=SU9_33783 PE=4 SV=1
------------------LARAAGWRYRVAWDRLPTDA-PVALDGTWWIVVPG-DTADAVRALAAAGANPRILDPH-GT-------------DRAALAKE
LEERAAD--TVAGTVSLLAESGGEDT-----GHRGVAAGALATLVLLQALHDADIPTRLWTLTRGAVRSGPDTAPDPWQAQVWGLGRVAALEHPALWGGL
IDLPAEGE------PAGLAAVLSGTAGEDQVALRGDGARARRLTPADTHDAPASGAYRW-TDGAVLITGGTGALGAHTARMLASRGASRLVLVSRRGPAA
PG------AEALRAELEAFGATVDLTACDVTDRDAVGRLAEGLAAA-GTPVRAVVHAAGVAAEQPLTDLVGGDFSAVTDAKVTAAEILDDVLGD-DLAAF
VVYSSIAGTWGSAGNGPYAAANAHLDALVERRR-ARGAAGTAVAWGPWSGGGMADD-RFQEEMLRRGVRALSPEGATAALAQALEHDDTTTVVDVDWDRF
AHVF------------------ASNR----PSPLLGHLTEP-AAAADEA------------------PARTEPAERLAAL----DAEARRGAVLDLVRAE
VAGVLGHQAVAVDRAFTDMGFDSLMAVELRTRLGVVSGLALPTTLVFDHPSPAEVADFLCARFEPD------
>tr|A0A0D8B5G3|A0A0D8B5G3_9ACTN Acyltransferase family protein,phosphopantetheine-containing protein OS=Frankia sp. CpI1-S GN=FF36_06391 PE=4 SV=1
------------------ESQADSWRYRIAWRPVPQSASAPASDGDWLLVVAP-ERVAAAVALEDAGAAVRRLVPA-AA-------------DRRTLATE
LTRLLAPIGAVAGVLSLLALDESAHP-----DAAATPLGLAGTVALLQALDDTGLDARLWIATSGAVSTSADPVTRPADALLWGLGAICAVEYPGRWGGI
VDLPDQVDE---EAARLLATALRAGHGEAELVVRSGGLLARRLVPAPTEARPPGSVADWAAEGTVLITGGTGALGGHVARWLAREGAAHLLLTSRRGERA
PG------AGELAEELRALGARVTIAAVDVGDRDALAEVIGGIPAE---PLRAVVHTAAVLDDGLVSELTLEQIDRVLRVKVGGALNLHELTRD-DLAAF
VLFSSIAGTAGITGQGNYAPGNAYLDAFAAYRR-AAGLVATSIAWGQWDGAGLAEP-DVERILGRYGLLAMDPQPAVRALAGALASDETHAIVAADWPVF
----------------------YRSR----PHPLVHELPEV-AAERSALA----------ERSGAGDGDGPVLAARLAEL----DGPARREALLAIVRDH
VAAVQGHDAVDVDRGFRDQGFDSLAAVNLRNRLIAETGLSLPVSLVFDYPTAAALTDHLLGELVPD------
>tr|A0A0F2SS02|A0A0F2SS02_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces rubellomurinus subsp. indigoferus GN=VM98_28580 PE=4 SV=1
------------------R----GWRYRVEWRRRADPD-RPAPQGRWLLLAPP-GRA-----------DVER-EVA-AA-------------DRESLARL
LRDTA----GVAGVVSLLPA--------------------VGVLVLLQALEDSGVDARLWCVTRGAVSVGADRVTSPEQARTWGLGRVAALELPHRWGGL
VDLPDG-------GAVDLAAVLTADEGEDQLAVRPTGTYVRRLVRAPLADP-EGGIAPWTPSGTVLVT-GTGSVAARVARWLLDRGAEHVALTGPVGG--
--------PDADRADLSDLGGRISCSGREADDLAGTAALVQRLAEQ-GRPVRAVVHTAAGTTLAPLLRATPADLAATVAATVTPAVHALDLLP--DLTAA
VLFTSVSGVWGTGEHAAFAAANAQLDALAEQRR-AAGAPVVSVAWGVWNTLTPGEAADALARPARHGVPLLDPDRALAALDEITARGERGVIAEVDWARF
APLF------------------GSAR----PTRLFAELPEA-STAAPPQA----------VT--GDAERAADLRRRLAAA----AGPERDRLLLELVRGH
AAAALGHGAVAAERPFRELGFDSLIAVRLRNGLSAATGVPLPLTLVFDHPTPAALAAHLGERLGGG------
>tr|A0A0M2GG63|A0A0M2GG63_9ACTN Polyketide synthase (Fragment) OS=Streptomyces variegatus GN=UK15_38905 PE=4 SV=1
------------------RHVADSWRYRIAWQPLADGP-EPVLSGTWLAVLPQ-GWAAGCLSLTVRGARTLPIGTA-DG-------------ERAPLAER
IASAVETDGPVAGVVSLLALADAPHA-----QQPAVSQGLAATLALVQALGDAEVAAPLWCLTTGAVSTSPDRPAHPGQAQIWGLGRVIALEHPDRWGGL
VDLPETPDE---RSLTRLTAALSDPAFEDQLAVRASGTAVRRLTRAPRET---ADATPWQPHGTVLVTGGTGALGAEVARWLARDGAGHLLLTSRRGPAA
DG------AAELRDELIALGADVTIAACDAADRTALAALLAAVPA--EQPLTAVVHAAGVLDDGVLDGQTPERFARVLRPKADAARNLHELTADHDLAAF
VLFSSVAGTLGNAGQANYAAANAYLDALAEQRR-ADGLPATTIAWGPWAGAGMAAAEPDGDRLRRIGLAPMDRDTAVEALRRTVEGGAAVAVADIDWARF
AEVF------------------AAQR----PSALLSDLPEA-RGHLAGSG----------GQVTD----AAEWRLRIAAL----PENEREPALLELVREQ
VALVLGHAAVPADKAFKDTGFDSLAAVQLRNRLGQVTGLRLPATLVFDHPTPTALARFLTAESAGS------
>tr|A0A0M2GBT8|A0A0M2GBT8_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces variegatus GN=UK15_38940 PE=4 SV=1
------------------ESVVDSWRYRITWKPLAEAA-PTVPAGTWLAVVPE-AWVDATLAMDGRGARTVVLGSA-EG-------------DRAALARR
LTELV-EEGSVAGVLSFLALDETARP-----QHPGVTAGLWSTLELVRALGDADATAPLWCLTRGAVSVGRDRLASPAQAQAWGLGRVVGLEHPDRWGGL
VDVPETADE---PALRRLLAVLAGSGDEDQIAVRASGVFVRRLAHAPRRT---ADGAPWRPRGTVLVTGGTGALGAEVARWLARNGAEHLILTSRRGIEA
PG------AGELRRELAGFGAEVTVAACDVADREALADLLAALPP--ERPLRAVVHAAGVGQYAPLAGMDADEFARVVTGKVAGARHLHELLLDTPLDAF
VLFSSVSGIWGSGGQGAYAAANAYLDALAQQRR-DSGRPATALAWGPWAEVGLAAADTGEAQLRRGGLLPLAPESAIAALQQAMDADDTATIADVMWEQF
LPGF------------------AVAR----PRPLIGDLPAV-RKVLDAER----------PHDTG---ADSALARRLRGL----SEADRGRALLELVRSE
TAAVLGHDDVAAERPFKELGFDSLTAVEFRNRLNSATGLTLPSTLVYDFPTAAVLAERLGRELRGA------
>tr|H0KA26|H0KA26_9PSEU Beta-ketoacyl synthase OS=Saccharomonospora azurea SZMC 14600 GN=SZMC14600_19884 PE=4 SV=1
------------------EAALDDARYRVTWQPVPDNP-AATVTGRWLLLAPE-DLT------TAFGDRVDVR--D-TP-------------DRAMFADL
P--------DYEGVAIVV---------------SAGDRGARESLLAAQALGDRGIDAPLWLLTRGAVSAGRDRPTDPVQAQVWGLGRVVGLEHPERWGGV
LDLPDVVDE---QAAARVLGVL-AGGRETEVAVRPDGVYARRLVSSPQRA----GTDSWSPTGTVLVTGGTGALGGEVARWAAREGAKRLVLTSRRGAEA
PG------ASELADELREFGVDVTLAACDLADRDAVAALVKDCG-----DLTAVVHAAGVSQSTPLADTTPEEFAAVIAGKVAGAMHLHELTA--DLDAF
VVFSSIAGVWGSAGQVAYSAANAALDALVEQRR-ADGLPGTAVAWGPWAGGGMAGGD--GAQLARMGLSGLAPEQAIAALARAVGSGDVTTVADVDWSRF
LPIF------------------TATG----STPLFTALAEV-DAD--------------------ADQEVTDRRAELAAL----APADRQRTVLDLVRAE
AAIVLGLNAVEPARPFRDLGMDSVTSVELRDRLATVSGVRLPATAVFDHPTPDDLVAHLIAEITGD------
>tr|A0A0A0NLN1|A0A0A0NLN1_9ACTN Uncharacterized protein OS=Streptomyces rapamycinicus NRRL 5491 GN=M271_45455 PE=4 SV=1
------------------KSAADRLRYQVTWKPLPGATS-GVPTGTWLVVLPY-GYAAQVAALNRQGLRTTTLGPEPP--------------DRAAFAGM
LRGALDH--DIGGVLSLLALDQRVRS-----GSATLTEGSAATLALVQALGDLGSGHRLYCATQGAVTVGADRLSAPEQAAVWGLGLAVALEQPDRWGAL
VDLPDVFDD---RAARTLLAALAGPGDEDQLAIRATGAFVRRLRSHPLTTG-A-TKPEWRPRGTVLVTGGTEGLGRHAARWLAGAGAEHLVLTVGSDPEA
PHEA--PHVVALRDELSGLGAKVTVCPTDLTDRDAVERLLTGPAAY---ELSGVVHTADLARIAQTDATSTDELAETLAAKVDGLLHLDTLLAD-ELDLF
VVFSSVAGVWGGGGQGLIGAANAQLDALIERRR-ARGLVATSVAWGVIDGFGVAADATAQEQLRRRGVLPMAPEAAMAALTHAVRHDDTLAVVDIDWSAF
VPAF------------------TSLR----PSPLIGDLPGV-QEIVDSLR----------TDDT--DGSASEFLRELAAG----SDAERERALMKAVREN
AAVALGHEAVKPQRAFQEMGFDSLAAVNLRNTLGAALGTRLPATLVFDYPTPAALVEYLRAELLGD------
>tr|A0A0F5A369|A0A0F5A369_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. MUSC164 GN=VT50_33550 PE=4 SV=1
------------------RSTVDGWRYRVTWKPVTDRS-AASLTGCWLVVAPA-GWAAGAVMLNERGVDVRRV--A-DD-------------DRAAVAER
L------AAVTGGVLSLLALAD---E-----GDG-DGDVLLRTAALTQALGDAGIGAPLWVATRGAVAVGRDGTVSPAQARLWGLGRVAALEVPERWGGL
VDLPETADE---RALGRLAEVLAGGGGEDQVAVRASGVFGRRLVRASVSAS---ASDSWTPGGTTLVTGGTGALGAQVARWLVENGAAHVLLTSRRGLDA
PG------AAELRDELAASGARVTVAGCDVADRDALARLLADIP----APLTAVVHTAGVLDDGVLDSLTPERFATVLRAKADAALALDELTRD-ELSAF
VLFSSISGTFGAAGQGNYAAANAYLDALAERRR-AQGLPATSIAWGPWAEGGMATDGALEQRLRRGGLPPMDAELATGALQRALDLDDTVTVADIDWERF
APDF------------------TAAR----PSRLLADLPEL-RAAAENTA----------T----PAADGSSLAARLAGL----AEAERDRLLLDLVRTQ
VAAVLGHESIGADRAFGELGFDSLTAVELRNRLGAASGVQLPATLVFDYPTAAALAGYLRGELIET------
>tr|A0A0A0N8P6|A0A0A0N8P6_9ACTN Uncharacterized protein OS=Streptomyces rapamycinicus NRRL 5491 GN=M271_09695 PE=4 SV=1
------------------EEPDESGVRPVAVYSRPED--QVRLPGERVGE--VEAWSSVVRRLTRAGSDAVALDAAGQPVISI-----ESLALRPISAEQ
LQAAQ--SRPETVVLSCPA--GGGED-----LVAGVGESLSAVLSSVQGEDRL-FGSRLVVVTCGAVATEMEDVADLVQAPVWGLLRSVQTENPGRFLLL
DHDPDHHDP---DADAVVRAIA--TGEESQLAVRGETVLVPRLSRVAKPAADLGTSTRLVSGGTVLVTGASGVLAGVMARHLVADHGEHLLLASRRGPDA
PG------AAELVAELEAAGASVTVAACDVADREEVRELLAAIPGQ---PLRGVVHTAAVVDDGVVEGLTDERVQRVLAPKVDAAWHLHELTQD-GLEAF
VLYSSVASTLGAGGQGSYAAANAFLDALAQRRH-AHGLPAVSLAWGLWA-SGITSQ-TDIARMARGGTTGLTTEEGLVLFDTAQSVGRPHMPVRMDLTSH
QAH-------------------PEVP----VPAMLRNLIRT-PLRKAATG----------QS------GAKQWRDRLLGA----SPEERERLLLDLVRIS
TATVLGHGDIDLEGEFLEMGLDSLTAVELRNQLGGATGLRLSTTMVFDHPTPADLAVHLADELNTL------
>tr|A0A0A0N9L0|A0A0A0N9L0_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces rapamycinicus NRRL 5491 GN=M271_09710 PE=4 SV=1
------------------EEPDAAGLRPVAVYSHLED--VVRLPQECVAE--AEAWSSVVRRLTRAGSDAVSLDAAGQPVVSV-----ESLVLRSISAEQ
LQAAQ--SRPETVVLSCPM--SGD-D-----VVVGVGESLSAVLSSVQGEERL-FGSRLVVATCGAVATETEDVADLVQAPVWGLLRSVQTENPGRFLLL
DHDPEH-------ADAVVRVLV--AGEEPQLAVRGGTVLVPRLSRVAKPAVDLEASVPLVSGGTVLVTGASGVLAGVVARHLVVGRGEHLLLASRRGSDA
PG------MAELVAELEAAGASVTVAACDVADREAVRELLAGISAE---PLRGVVHTAGVVDDGVVGGLSDERVRRVLAPKVDAAWHLHELTRD-GLEAF
VLYSSAAATLGAGGQGSYAAANAFLDALAQHRH-AHGLPALSLGWGLWA-SGITSE-TDLARMARGGTTGLTTEEGLALFDVAQGVGRGVLPVRVDVRAF
RGR-------------------GGVL----VPALLRNVVRG-AVRRVAVG----------RD------GSGAWRDRLAGV----ASGERERLLLELVRSH
VATVLGHAGIDADRALKDLGFDSLTAIELRNQVGAATELRLPTTLIFDYPTPSAIARYLDGRLGAG------
>tr|S3ZC23|S3ZC23_9ACTN Putative Phenolphthiocerol synthesis polyketide synthase type I Pks15/1 OS=Streptomyces aurantiacus JA 4570 GN=STRAU_5687 PE=4 
------------------EAPDASGHRPISLHSRPEP--GVALPDDDHTQ--AGAWTATVRRLTPNGTDGVSLDATGAPVASV-----DALVFRPMSKEL
IERMSPNPHPAAVVWSAERSARAD-A-----RPESVSASLAEALAVVQADERF-AASRLVVVTRGAVVIGTAASPDPVAAAVAGLVRSAQTEHPGRFVLV
DADVSG-------TESGLAEVL--ASGEPEVAVRDGAVWVPRLSRVAAAEP--GVVEAPWGSGTVLVTGAFGGLGRVVVRHLAERHGRDLLLVSRRGLEA
AG------AAELQAELAQLGTTATIAACDVADRDALAALLEESGE----GLSAVVHVAGVLDDGVVTALTPERLARVLRPKVDAALNLHELTSG-DLSAF
VLFSSASGVFGGPGQANYAAANAYLDALAAVRR-TQGLPATSLAWGLWAASDMTAD-ADLQRMARGGVLALDTERALTLLDLAPASEHPAVPIRIDTAAL
RNQ-------------------PPEA----LPALLSGLVRP-AVRRAQTG----------T---DPAARTESLAQRLAGR----TGAERDRMLLDLVRTH
VAGVLGYNAVELSRGFLELGFDSLTAVELRNRLTAETELRLPSTLIFDYPNPAALAEHLSEELPTT------
>tr|A0A0N0T538|A0A0N0T538_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. NRRL WC-3618 GN=ADL01_17410 PE=4 SV=1
------------------GAADENGRSAVSVHSRDEG--DVALPEEEAAD--AAGWSATVRRLSSAGADTVTLDETGQVVATV-----DSLVSRSVSDDR
LG---GGTFPATVVWPVDRPSPVDRV-----RPEDVSAFLAEALGVVQADERF-EGARLVVVTRGAAPVEGGADLDPAGAALWGLVRSAQVENPGRFLLV
DTEMAPLGT---GDAPALAAAL--AAGEPEVVVRAGAVWVPRLTRPTTRVSADETAASPYGEGTVLVTGAFGGLGRVVARHLAEHHRRDLLLVSRRGDAA
AG------ADELRAELEAVGAKVTVAACDVADRDALAALLDEAGG----ELSAVVHAAGVLDDGIVTSLTPERLDTVLRPKAAAALHLHELTAG-DLSAF
VLFSSAAGVLGSAGQANYAAANGLLDALAGIRR-AQGLPATSLAWGLWA-SDMTDG-TDLGRMARGGVAALSTDEGLALLDIAVTDAPATVPLRLDTASL
RAAA------------------GPDG----VQPVFSELVRT-PARRVDRA----------QARSNADPGTPALVKELAEL----SGADRERALLDAVRGN
VATVLGHEAVGATRGFLELGVDSLTAVELRNRLNSLFGLRLPATLIFDYPSPTALASYLDESLPQA------
>tr|W7VQN7|W7VQN7_9ACTN Type I polyketide synthase OS=Micromonospora sp. M42 GN=MCBG_06093 PE=4 SV=1
------------------RAVLDAWSYRVGWKRADITAGPPARPGAWLLVTAQDDRAEAVTALAEVGADVVRLDPA-GT-------------DRAGLARR
LGDA-LADGPVTGVLSLLGLRDQPHP-----AHPAVPVGTAATLLLLQALHDTGATTRLWCLTQGAVSTGDDTVHAVIQSGLWGLGLVAGLEHPHLWGGL
VDLPEQADA---TAWDRLARVVTGAGDEDQLAVRPSGVFVRRLVRSAPAAP--DTAQRWRPSGTVLVTGGTGALGAHVARWAAANGAEHVVLTSRRGGDA
PG------AVELREELIAQSVRASVVACDVAERDQVAALLARLDED-PAPLTAVVHAAGAGESGLIADTDLAAFAGVLDGKVAGALHLDALLGDRPLDAF
VLFSSIAGVWGSGGQSAYAAGNAFLDALAEQRR-GRGLAATSVAWGPWADGGMATGE-AQQMLARRGLTAMAPADAVHAMRYAAGLPRAATVVDVDWAVF
APAY------------------ASAR----PRPLLDDIAEA-REALHAHA----------VEQ--PGGAADALREHLLTL----PRPERVRHLVDLVRTH
ASAVLGHDRVKPQRAFKELGFDSLTAVELRNRLTGVTGLSLPATLVFDYPNPAVLAENLLDGLLPE------
>tr|A0A059WKJ2|A0A059WKJ2_STRA9 Modular polyketide synthase OS=Streptomyces albulus GN=DC74_7916 PE=4 SV=1
------------------AAPDATGRRALSVHARPDD--AIELPEPGPA---ERPWRTALRRLTPNGPDTWTLDPQGAPVLSV-----TGLILGTPTVEQ
SEAGT--EGPPPLVLAPLLGAPPGDD-----LPAAVRTTTTAVLELLQADART-ADARLVIVTRGAVAA-GEDVADLAAAPVWGLVRSAQSEHPGSFLLL
DLDPADALR---APD-ALTALL--DAGETQVAVRGGALTVARLTRAVDGPDAPHPVRAWDRDGTVLLTGGTGGLAGVLARHLVTGHGKHLLLAGRRGPDA
PG------ATALRDELAGLGAEVTVAACDASDRTALDALLAQLPPE---PLTAVVHTAGVLDDATVGALTPQRLDRVLRAKADAAWHLHQATRG-DLAGF
VLYSSVAGVTGGPGQGNYAAANAFLDALAAHRA-ARGLPGLSLAWGPWG-AGMTGA-ADLARLERSGMPPLTPAQGLALFDAAGARGAGLVATRLAQG-P
AAP-------------------GDGQ----VPALLRALVRG-RRRTAAAA----------GH------GRGP-ARRLAAL----DPAQRERALLDLVRTE
TAAVLGHDAVPAERDFNRLGFDSLMAVELRTRLAAATGTRLPAALVFDHPTPLAVARHLHSTLPGA------
>tr|G2NZK8|G2NZK8_STRVO Beta-ketoacyl synthase OS=Streptomyces violaceusniger Tu 4113 GN=Strvi_3972 PE=4 SV=1
-------------------STIDSWRYRATWQQLPDPAT-PALTGTWLVVAPAGQEHATVQALRAHGATALPLAVDAHDI------------DRAALRER
LGRLPE-EAQPAGVISLLALDQEPLAGH-----SAVPAGLGATVALLQALGDADISAPLWCVTQGAVATGRSLLPHPEQSQIWGFGRVAALEHPQRWGGL
IDLPTTMTH---HTAGRLAALLVAGQPEDQAAIRTTGTYARRLIRVPAGDT---APAPWEPSGSTLVTGGTGGLGAQLARWLAHRGAPHLHLISRSGPDA
PGA------SELSEELTALGTDVTITTCDASDRDALRQLIDTV-PA-EHPLTAVFHTAGTMELGQISELDPGRLQSVLRSKTLAAAHLHDLTQHLDLTAF
VLFSSNAATWGSGHQAAYAAANTYLDALADHRH-TRGLPATSLAWGPWGEAGMAADQHTLSHLKRRGLSPLPTDLAIASLHHALTHHDTAVIADVDWARF
GGTFTAQ----------------------RPSPFLAHLMPS------------A----AEAATPTDTADDNPLRQRLSAA----PAAQRHQILVRHIQSL
AATILGHDAIPPAQPFQELGFDSLTAVELRNQLAATTGLPLAPALVFDHPTPNALATYLGAELTG-------
>tr|X0N9F9|X0N9F9_STRA9 Beta-ketoacyl synthase (Fragment) OS=Streptomyces albulus PD-1 GN=P354_18905 PE=4 SV=1
-------------------AVADGWSYRAGWTPVTART----TTGNWLVALPDSVT---LDALRAQGLHT----------------------E--VL-DP
SEP--LADGPIDGVLSLLAL-DRPHPDL-----TSVPRGL--TTALLRAVEGSGKPVPLWCATRGAVAVDDRVLTNPLQAQLWGFGRVAALEYPRIWGGL
VDLPETPDA---RAVSGLLDVLA-G-AEDQVAIRAAGTFARRLARIAPGGT----GAGWTAHGTVLITGGTGALGAELARWFADAGAEHLVLTSRRGLEA
PGA------PELAAELTDRGTPVTIVACDAADRDALAAVLAIP-A--ETPLTGVVHAAGVMDAGMLDALTLERFEAVLRPKATAALNLHELTRELDLELF
VLFSSIAGSLGNAGQANYSAANTFLDALAEHRR-AQGLPATATAWGAWADRGMAT-Q-VADRVSRDGLIPMAPASALAALRQALAQGLTNVVADVDWTAY
APALTAV----------------------RPSPLLADLPEA------------RRVAA--PE--SARADASPLGGRLGAL----SADERERVVLQTVQEE
AAKTLGLDGIEARRAFRDVGFDSLMSVELRNRLATVTGLALPTTLLFDHPTPSAVTAYLLAEILG-------
>tr|A0A0F4K578|A0A0F4K578_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. NRRL B-1568 GN=VR41_12005 PE=4 SV=1
-------------------SAADNWRYRITWKPLATAA---PAAGPWLVLAPAAAR-----ALG---TDSVLVEVTAPDR------------E-----GR
LRE--LLGTRFTGVASLLALADESVPGL-----PDVPVCL--TATAVQAVADTGIDAPLWCLTRGAVSVGRSQVTSPAQAAVWGLGRVIALEHPQRWGGL
ADLPEQLDP---HTLRRLAGVLA-S-GEDQVAVRASGSYGRRLAHAPAARP---ARPAYAPAGTVLVTGGTGALGGHVARWLARSGAQHLLLTSRRGPDA
PGA------GELRTELTELGAEVTIAACDTADRDALTALLAVP-A--DRPLTAVFHAAGVVEDGLVEDLTPHGFSAVLRAKATAARHLHDLTQELDLAAF
VLFSSTAGTIGAAGQGNYAAANAYLDALAEHRR-ARGLAATSVAWGPWAGSGMVA-DGIENRVRRGGYAPLPVDQAVAALRHAVEHDDTTLVADIDWSRF
ARTLAAI----------------------RPAPLVADLPEI------------RQSGD--QD--IAATPETGLRRRLAEL----PEAERGRFLLDMLRTQ
VAAVLGHARVEPDRAFRDLGFDSLTALELRNAVTATTGLALPASLVYDHPTMLELAAFLLAELAG-------
>tr|L8EHG5|L8EHG5_STRRM Beta-ketoacyl synthase (Fragment) OS=Streptomyces rimosus subsp. rimosus ATCC 10970 GN=SRIM_32576 PE=4 SV=1
-------------------AAADRFSYRVHWTPRTASG----ATGHWLVVLPEGGT---LDALHDLGLHT----------------------D--EL-DP
DAP--IADTPLDGVLSLLAL-DRPHPDL-----PSVPRGL--TTTLLHALESAGVQAPLWCATRGAVAVDRHALDSPVQAQIWGLGRVAALEAPQSWGGL
VDLPENLDR---RAVSALLDALA-S-EEDQVAIRPAGTFARRLERIAPGGT----GARWSIHGTVLVTGGTGALGGHLAHWLADAGAEHLVLTGRRGPQA
PGA------QELAAALTDRGVKVTLAACDAADREALAAVLAIP-P--ELPLTGVVHAAGVLDDGVLAALTPERFETVLRPKARAAQHLHDLTQGMDLDLF
VLFSSIVGVLGNAGQAGYAAANAHLDALAAHRR-QQGLPATSVSWGPWAGEGMAT-D-AADRLSRDGLLPMAAAPALAALRQALAQDMTHVVADIDWSAY
APALTAV----------------------RPSPLIGDLPEA------------RRAPA--D---GPRRERSPLRDRIAAL----PPAEQEQALVTTVREE
AAKVLGHDTVDVQRAFREQGFDSLMSVDLRNRLSAATGLRLPATLLYDHPSTVAVAAYLRSEVLG-------
>tr|R4LC06|R4LC06_9ACTN Modular polyketide synthase OS=Actinoplanes sp. N902-109 GN=L083_2493 PE=4 SV=1
-------------------SRTVGWRYRVTWAPVTKLG----VSGTWLVVRPAGVG------LAARGAEVVEADVRGL----------------------
------DVGAVAGVLSLLAL-DSSMVDF-----PSVPQGL--TLELVQALGAAGITTPLWIATRGAVATGADVLTSPIQAQAWGLGRVVGLEHPDRWGGL
IDLPAVVDD---RASARLAAVL--C-NEDQVAIRAGAVLGRRLGHAPKPR-----DEQWQPRGTVLITGGTGAIGGHVARGLAARGASRVLLTSRSGPAA
AGA------AELAASLASTGTRTDVLACDASNRDELATVIATR-E-----LSAVMHTAGVLDDGVIERLSPSRLSTVLTAKATSAALLDELTAHRDLDAF
VLFSSAASTLGSAGQGSYVAANAYLDALAENRR-SRNLPGLSVAWGVWGGGGFAE-SAVRKRMQRTPMPPMDPDLAVRALFEAGHGADAALIMDVNWEQM
AGGPRSM----------------------RAMPLLRDLPEI------------RDLNE--PT--VPAIGEGELGRRLTGL----SRVDQERLLTDLVRVE
AAAVLGHEGVPARSAFKDLGFDSLTAVELRNRLSAASGLRLSATLVFDYPTPAVLASHLRAELTG-------
>tr|G2G4P4|G2G4P4_9ACTN Modular polyketide synthase OS=Streptomyces zinciresistens K42 GN=SZN_02237 PE=4 SV=1
-------------------STIDGWRYRVSWKPVPDPAE-GPL-GTWLVVVPAARAGDEVAGLERHGAGVVSLVLDERDL------------DAG---GR
LREVAGQ--ELGGVLSLLALDEEPCPGH-----PALSGGG-R-LVLAQAMVEADVPARLWCGTRGAVSVGRSRLTGAVQSQVWGLGRVVALEHPAVWGGL
VDLPESLDE---RGAARLAGVLSAGKGEDQVAIRGSGVFARRLVRADASGG---AERPWRARGTVLVTGGTGALGGQVARWLARSGARHLVLTSRRGPDA
PGA------AELRDELEALGARVTVAACDVTDRDALAAVLADV-PE-EFPLSAVFHAAGVEQAAALVGMSLADAAAVVSAKTAGAAHLDELLGDRELDAF
VVFSSIAGVWGSGGQAAYSAANACLDALAQDRR-ARGLAGTAVAWGPWAEGGMAAA--VERELARRGLRVMAPALAIAALQGAIEGGDTAVVADMDWERF
APAFTLE----------------------RPSSLIGDLPEV------------AKAGAP-----GGAAASAGLRERLAGL----TEAETDRALLDLVRGH
VAAVLGFETVDAGRAFKELGFDSLTAVELRNRLNAETGLALSATLVFDYPNASVLADHLRAEVL--------
>tr|A0A0D0V4R3|A0A0D0V4R3_9ACTN Beta-ketoacyl synthase OS=Micromonospora carbonacea GN=TK50_11430 PE=4 SV=1
-------------------AALDAWTYRVAWEAVHPAS--TRPPGRWLVVTPTLPAGTRVGALRRGGARVEVLGVRGGVG------------RGEALRGP
GGQ--VAETGWAGVVCLLPE-RAPLPDA-----PAVPAGT--LLTLAQALADTGLPGRLWCLTRGAVSVGGGRIADPSAAAAWGLGRVIALEQPDRWGGL
VDLPGSGIRTSRAGGDALLAVL--A-GHDQVAIRPQGVLGRRLVPAAPP-V----GSGWRPSGTVLVTGGTGALGRHTARWLLANGAAEVVLASRRGPEA
PGA------AELIEELRGTGA-VRVVACDVTDAAAVDALVALP-A-----LTAVVHTAGIVDDGVLDGLDVDRMQAVLAGKATAARVLHDATAGRDLDAF
VLFSSLAGVVGSAGQGNYAAANAYLDAFAAWRH-AQGLPATAVAWGAWAADGMAA-AALTARLTRGGINPLPAAEAVTALGRVVNAAGPAVVADVDWGRL
AASW--G----------------------RPNPLIAALPGV------------PAVGP--------------VR----AV----VVGRSLPQLTELVRTQ
AAVVLGYRP-LPERTFRDLGFDSLTAVELRNRLTAETGMTLPATLVFDHPTVAELAAHLHGLTNR-------
>tr|D9T6W8|D9T6W8_MICAI Beta-ketoacyl synthase OS=Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442) GN=Mica
-------------------AVVDGWTYRIDWEPVRPAA----ATGRWLVVTADA-----AGTLTGAGAHVDTLTVAPGVD------------RAELL---
-----RGEQGWTGVLCVLPA-TRALPDA-----PAVSVGA--LLTLTQALADAGLPGRLWCLTRGAVRVGAGTLTDPWPALAWGLGRVVALEQPDRWGGL
IDLPARAE-R--TAADALLAVL--A-GHDQVAIRPQGVFGRRLVPAAPP-A----GAGWRPAGTVLVTGGTGALGRHVARWLLANGAAEVVLASRRGPAA
PGA------AELVDEL---GA-VRVVACDVTDRAAVDALVALP-E-----LTAVVHTAGVIDDGVLDGLDLGRMQTVLDGKVRAARVLHEATAHRDLDAF
VLFSSLAGVIGSAGQGNYAAANAYLDAFAAWRR-DQGLPGTAIAWGAWAEDGMAA--ALTARLARGGVDALPVAEAVTALGRLVNTADPAVVAAVDWGRL
AASW--G----------------------RPTPLIAALPGV------------PAVGP--------------VR----AV----VVGRSLPQLADLVRTQ
AAVVLGYRP-LPERTFRDLGFDSLTAVELRNRLTAETGMTLPATLVFDHPTVAELAAHLHGLTA--------
>tr|C9YYI0|C9YYI0_STRSW Putative type I polyketide synthase OS=Streptomyces scabiei (strain 87.22) GN=SCAB_83891 PE=4 SV=1
-------------------RRADGWRHRVGWRPLTLAPR-ASLSGRWLVVLPAADSGADLAALTAAGAEPVPVVVSAPDQ------------DRE---AS
LRAASGA--PVAGVFSLLAEETRPHPAQ-----PDVPAGL--TLALVQALGDTGTDAPLWCATRALAAVGGGRPGASAQAAVAGLGRTVALERPDTWGGL
VDLPAVLDE---RAADRLGAVLAAVTDEDQVAVRSSGVYGRRLLPVGPGRP---AEARHSPSGTVLITGGTGGIGAQVARELAERGAVHLLLLSRRGPDA
PGV------DALRAELTALGARVTVAACDVADRAQLTAVVAAI-PE-EEPLTTVVHAAGVLDDGTLDALDPARLATLMRVKVTAARTLHEVTDGIGLADF
VVFSSFMGVLGSAGQGNYAAANAALDALVAERR-AAGLPGTSLAWGAWAGGGMVDDR-IADRLRRLGITPMEPRAAVRAMTAALADHDELCVADVDWQRF
REA-VGL----------------------RATALLSGLPGA------------AGAPAGPAEQEGQEGQDGQVRGQLAAL----PAAERSRHITDLVRTH
AATVLRHTDIAPGRAFAELGFDSLTAVELRNRLGTATGLRLPTTLLFDHPTPQALAAHLLAELAP-------
>tr|A0A024Z3Y3|A0A024Z3Y3_9ACTN Polyketide synthase OS=Streptomyces sp. PCS3-D2 GN=AW27_07040 PE=4 SV=1
-------------------RRAESWRYRVTWTPLSVAPA-DGLAGRWLALRPESDA---LDALRDAGADLIPCVVAGPGT------------TRG---VL
LT---DAGQPIAGVLSLLSWEERTHPQH-----PDLPGGP--TLALAQALEDAGIDARLWTLTTGTAALGGARPGTVGQAASAALGRTAALEHPHRRGGL
VDLPEVLDA---RAARRLCAVLAGVADEEQVAVRSTGIHGRRLRPAPSASP---VRPGPKWQGTVLVTGGTGGVGSHTARWLAGQGAERLLLVSRRGADA
PGT------DALRAELTALGAEVAFAACDVADPVALAALIDAI-PV-QYPLSAVIHAAGVLDDGVLDALDPARLAVVMRAKLTAARNLHEATAGLNLSAF
VVFSSVMGVLGNAGQGNYAAANAAVDALVAARR-AAGLPGTSVAWGAWAGPGMLADD-VAARLRDFGMPVMEPETAVTAIGRALAEDDALVVADIDWRRF
TAG-MGL----------------------RSTALLDALPDP------------AGADTGAPPSADGAHDADTLRQQVAVL----PRHERVRTLTELVRAH
AAAVLRHNTVQPAKAFSALGFDSLTAVELRNRLATATGLALPATVLFDHPTPSALADRLLAELG--------
>tr|F1ADL8|F1ADL8_9ACTN BafAI OS=Streptomyces lohii PE=4 SV=1
-------------------RKAESWRYRVAWTPLSVEPA-DGLAGRWLALRPESDD---LDALGEAGADLLPCVVDDPGA------------TRG---AL
LTEITETDQPIAGVLSLLSWEERPHPDH-----PDLPGGP--TLALAQALEDTGIDARLWTLTKGTAVLGGARPGHVGQAASAALGRTLALEHPHRPGGL
VDLPEVLDV---RAARRLCAVLAGVADEEQVAVRSTGVHGRRLRPAPPSAR---ARTRPLWKGTVLVTGATGGVGSHTARWLAGQGAERLLLVSRRGADA
PGT------DALRAELTALGAEVAFAACDVADPAALAALVAGI-PA-RYPLSAVVHAAGVLDDGVLDALDPARLAVVLRAKLTAARNLHEATADLGLSAF
VVFSSVMGVVGNAGQGNYAAANAAVDALVAARR-AAGLPGTSVAWGAWAGPGMLADE-VAARLRDFGMPVMEPETAVTAIGRALAEDDALVVADVDWRRF
ATS-TGL----------------------RSAALLDGIPDP------------AAAGTTAPS--ETGGSADALRQRIAVL----PRHERVRALTELVRAH
AATVLRHDAVRSTQAFSALGFDSLTAVELRNRLAAATGLALPAAVLFDHPTPSALADRLLADLDL-------
>tr|A0A060ZUG5|A0A060ZUG5_9ACTN Beta-ketoacyl synthase OS=Streptomyces iranensis GN=SIRAN6342 PE=4 SV=1
-------------------LVTEPWTELAVWPPQGATPI-AVEQGAWRLGEEVGFPGAPRFGLHAAGAGALRVRLSERSS------------NAVSLRDQ
VRAARGG------HESLFRLDWVPAPAT-----GAVTGDWAAALLQEWLADERFAGSRLVLLTRGAVETEPGGVADLPYAAVRGLFRSAQSENPGRLVLL
DVDGEESSY---RTV-----PAALGVDEAELALRAGVALAPRLARVPVTDV---TVPSYDPNGTVLITGATGTLGGLFARHLVAHGVRHLLLVSRRGADA
EGA------EELGAELTAAGATVTWAACDAADRHALAATLAAV-PA-EHPLTAVVHTAGVLDDGVLGSLTPERVARVLRPKVDAALNLHELTRDHELSAF
VLFSGAAAVFGAPGQASYAAANSFLEALAQHRV-AQGLPATALAWGLWAGAGMGSELVDLRRIARGGVAPIAADEGLALFDAARADGAAVLPMRLDYAGL
RTEATA----------------------------TGTVPAL------------FRGTPVRRAAATAAAEGSSLAQRLVGL----ARPEQDRELLELVCGR
VAAVLGYDAVEAGRAFKELGFDSLTAVELRNDLKTVTGLRLPATLVFDYPTPAALAGHLREELLG-------
>tr|I2NBQ7|I2NBQ7_9ACTN Beta-ketoacyl synthase OS=Streptomyces tsukubaensis NRRL18488 GN=STSU_00535 PE=4 SV=1
-------------------RPADDWRYRITWQLSDTHPT-GPASGIWLLVGDDPDA---AEALTRHGADVLTATDVGDL---------------------
-----DPVAEVTGIVSLLAL-DTPDAEF-----PWVPSGT--TVELIQAVHRAGAAVPVWVLTRGAVQTGAGATTSPAQTAVWGLCRAVGLERPELWGGL
VDLPADFTA---EAGTGLASIL--T-SEDQVALRPDGVFLRRLVHAEPRRE----TGKWTPRGTVLLTGGTGSIGVTVGVWLAEQNAQRVVLTSRSGPLA
PGL------PALAASVANGGADVDVLGCDLGTPEQVNGMVGIQ-ET-GPGLSTVLHTANLPYLAWVEDTEREGLAAALGAKAAGAVHLDQATTGLDIDEF
VLFSSISATWGSNDHGAYAAGNSFLDGFAETRR-SRGLPATSIAWGVWDSRDWDALDVTPSRLRRQGMNFLETQRALTALGEILTEDETFIVADVEWEKF
APVFCAA----------------------RPRPLLDTIPEA------------REDPARPAQ--TATTERGEYATQLAPM----TLGERRRTVIDLVRSH
ATAVLGHDEINATRAFRDVGYDSLTAVELRNRLNTVTGIRLPSTVVFDHPNPTALAEEILTELFG-------
>tr|A8J706|A8J706_9ACTN Modular polyketide synthase OS=Streptomyces cyaneogriseus subsp. noncyanogenus GN=nemA4 PE=4 SV=1
-------------------AVVDGWRYRVVWRPVSRSGG-GVVGGVWVVVVPEGVVGAAVEGLERAGVCVRVVAVEGGCA------------DRV---ER
LREVCGG--PVGV--------------------LAVCGGG-A-LVLGLVQAVEGLGVPLWCVTRGAVSVGEGRLGDPGGAVVWGLGRVAGLELPDRWGGV
VDLPEVVDE---RVVEGLLGVLSGGGGEGEVAVRASGVFVRRLVRAPGGGA---EAGGWRPRGTVLITGGTGALGAHVARWMVRRGAEHLLLVSRSGREA
KGA------GELRAELTAMGARVTIAACDVADRGALAELLAAV-PE-DCPLGAVVHTAGVVDDGVLDALTPERLEGVLAAKAVGARNLHELTRGADLSAF
VVFSSAAATFGSGGQGAYVAANAYVEALAVHRR-GLGLPSTAVAWGAWAGGGMAAD--AATRMDRRGIRPMDTEPALSALGQVLDRNETCLIADIDWERL
PAADGLA----------------------R---LLSDIPEA------------RLARPA-----TGTEAPGSLRARLAAL----EPAERDRALLDLVRTH
TATVLGHTAVPADRAFRELGFVSLNAVELRNGLNTATGLRLPSTLVFDYPNPSALATHLGTLLST-------
>tr|S4W6S6|S4W6S6_STRCH Type I polyketide synthase AVES 4 OS=Streptomyces coelicolor GN=aveA4 PE=4 SV=1
-------------------EVVDGWRYREVWRPVSGGGV-GGLSGAWLVVSEGEAG---AEGLERCGARVVRVEVEAGCV------------SRE---GH
LREAVDG---VGGVVSLVGWGS----------------GV--SVGLVQALGDVGVGARLWCVTGGAVSVGGRAVWGPASGVVWGLGRVVGAEAPDRWGGL
VDVPELVDE---RVVDGLVGVLAGGGGESEFAVRSSGAFVRRLVRAPLEE----AEREWRPRGTVLVTGGTGELGAHVARWMARRGAEHLLLVSRRGESA
QGV------EELRADLMGLGARVSVVACDAADREALAEVLRAV-PA-ECPLGVVVHAAGVVDDGVLEGLSSERVTGVLRAKALAAWNLHELTRGADLSGF
VVFSSAAATFGPAGQGSYAAANAYVEAIVRHRR-GEGLPGLAVAWGPWAGGGMAEGA--VGQMRRRGLAAMTPETALVALGQALDHDETCVVADIDWDRF
TANLPGS----------------------RLSPLISDIPEA------------RLAGLD-----TATASPDSFSARLKAM----DTAEQERALLDLVRTY
AATVLGHTAVRPERAFRDLGFVSVSAVELRNRLNAVTGLLLPTTLIFDYPTPSALAGYLKEQLEE-------
>tr|S4Y352|S4Y352_SORCE Uncharacterized protein OS=Sorangium cellulosum So0157-2 GN=SCE1572_38665 PE=4 SV=1
-------------------RAGSQWPPLAGWSLLKEIEE-ASSLGSWGIAAGHSVGGSVVAELEPFRERTLVSTVTGEGI------------DGESYWEA
LGALHPA-----RCVPLPGYPWAPADAG-----PEFAAQLGAGLAAWWAEGEDALDARLWFVTRGAVSVGAGPVTAPAQAALWGLGRTLSLEHPEVWGGL
VDLPPSPGE---HDVAALAAVLS--PGEDHVALRASGRYVERLVRCAGA-A---AAPAWSTSGTALITGGLGALGRHVARWAAQRGARHLVLTSRRGASA
-GD------RDFLTSLEALGARVTVAQADVADAAAMAAVLAID-AR-LPPLSAVFHLAGVSDQTPLSALDGAGLRRVLAPKVHGTAALDALTRGRPLDAF
VCFTSIAAVWGSARQAGYAAANAFQDALVRARR-AAGAPAVAVSFGPWRGGGMATSA--IASLEERGVRAFGPEQAMAALSFCMTAGAAQVVADVDWPRF
CAVVESS----------------------GPRPLLSEMPRV------------AAPGDAA---PAPGDAAPALLGELAAA----PPRERRRMLQRRIHAL
VAETLGFDEVSPTRGFFELGMDSLMAVDLCQRLGLALGRPLSSSATFNHPNVVAMADFLLEELSP-------
>tr|D6C474|D6C474_9ACTN Modular polyketide synthase OS=Streptomyces nanchangensis GN=meiA4 PE=4 SV=1
-------------------GVLDGWRYREAWRPVGDGGP-GAPTGRWLVVAADGVD---VEELERSGARAA-LHAAEGCV------------ARE---ER
LRAELGP--EVDGVALLLAGSG----------------GG--LLVWLQALGDVGVAARLWCVTRGAVSVGGGAVVSPGLGQVWGLGRVAALEAPEVWGGL
VDVPDPLDA---RAARSLVRALAG--PERECAVRASGVFVRRLERAPLAGE---PGREWRPHGTVLITGGTGGLGAQVARWLAGRGPVHLLLLSRRGEAA
EGA------AGLRDELAGLGARVTVAACDVADRDALTRVLAGV-PE-DAPLTAVVHAAGALDDAVLATLTPERLEAARQAKAVGAWQLHELTRGADLTAF
VVFSSAAATFGSAGQGGYAAANAEVDALIQHRR-GLGLPGLSVAWGAWAGGGMADAAADAGRLRRHGMAAMDPRLALRALGHALEHDETCLVADIDWRAF
VDNAPAT----------------------GLDPLISGIPEA------------RTAGRG-----AAE-AAGTLRARLAGL----AADEQRRMVVELVRTH
AAAVLGHAAVPPERAFRELGFDSLTAVELRNRLNAATGLRLPTTAVFDYPHPAALAQHTYEQLFG-------
>tr|E2Q520|E2Q520_STRC2 Modular polyketide synthase OS=Streptomyces clavuligerus (strain ATCC 27064 / DSM 738 / JCM 4710 / NBRC 13307 / NCIMB 12785 / N
-------------------ARVESWRYRIGWQPLPDAP----HTGTWLVLVPAPSA---LRALRDAGAAVTRITLDGTET------------------AR
LRA--ALAGPPAGVLSLLAT-DRPHPRH-----PSVPVGT--GLALVQALGDAGIDAPLWWATRGAVSTGRAGPVSPAQNTAWGLGRVAALEHPRRWGGL
VDLPADLDA---RAAARLCAVLSGG-DEDQIAVRATGVHGRRLLRAPLAAA---PRRTWTPRGTVLITGGTGGLGAYLARRLARGGAEHLVLVSRRGPAA
PGA------AELTAELTALGVRTTVAACDITDRDALAALVDLE-RD-GCTIRSVLHAAAGGSLVALDDTDLDEFATTLHAKAGGAAHLDALFDRDTLDAF
VLFSSVSAVWGSAVHGAYAAANACLDGLAENRR-ARGLTATSVVWGIWSPEHGGGMALAEEQLRAQGVLFMPPALCAAALQQILDHDETVVVADIDWSRF
ATVFTTG----------------------RPSPLIGSVPEA------------RAAPNTPAD--TAGGAPAPLRDRLRDL----TGPERDLLLTDLVRTR
AAAVLGHDTVTPDRAFRDLGFDSLTAVELRNRLNEATGLRLPVTVVFDHTSPTALARHLRTRLLG-------
>tr|A0A0A0NM24|A0A0A0NM24_9ACTN Uncharacterized protein OS=Streptomyces rapamycinicus NRRL 5491 GN=M271_46360 PE=4 SV=1
-------------------STVDEWRYRVIWRPKSGTPA-ASL-GPWLLLAPSSRPGDPREALAAHGADVVLVELGADDA------------HRA---ER
LRAATAGLDTLSGVLSLLPLDERPYPAH-----PVATTGL-L-LALIQALDDLGVRAPLWCATQGAVSIGSSPLTSPAQAAVWGLGRVAGVEYPDSWGGL
IDLPRTMDA---RAGARFAGVLADGGPEDQAAIRASGVMLRRLEPAPLGNP---ARRTWKPRGTVLITGGTGALGSRLARWLAHNGAEHLVLTSRRGLAA
PGA------EDLVAELAEQGTRVTVAACDVADRAALQRVLASV-PD-DRPLTAVIHAAAYIDLAGLGATTSAEFAQVMDAKVAGAAHLDELLGDTPLDAF
VLFSSVSGLWGVGDHGAYAAANAYLDALAERRR-ANGLTATSVAWGVWDATGDNMP-LDLDQLRRRGLRFMDPELGIAALRQTLDHDQTHLIADIDWENF
IPVFTSA----------------------RPSPLLDELPAM------------RRIDPAGAVTNASADASSGLRQRLTGL----TPAEREHTVLELVRAQ
VVSVLGHDAVDSERAFKDLGFDSLTAVELRNRLNAATGLRLPATLAFDYPSTAVLSDHILTELTG-------
>tr|F8JL01|F8JL01_STREN FscE OS=Streptomyces cattleya (strain ATCC 35852 / DSM 46488 / JCM 4925 / NBRC 14057 / NRRL 8057) GN=SCATT_p14450 PE=4 SV=1
-------------------IGDEPWT---PAPPADAERV-ELDRAMWRRGDEVLLP---GFHLHATGATTLRVCLERSGD------------GPVRLWED
VPAGTGG---ADGDVTVVAAPDTPAGAD-----PAQAAVWGATLGLYPGLGTEGAGVDGWTYARGLVEVGPGKVLVAAGHIARALGDVYATAHPAKWDTL
RALGYPDSH---IAGSRDTGVLNSGLDASVRLLRPGGHLLTRLYPEPPVTT---LPAPLDPDGTVLITGGTGALGADVARHLVTHGARHLLLTSRRGPAA
DGA------EQLREELARSGATVTVTACDAADRDALAAVLSEV-DP-AHPLTAVVHAAGVLQDTTLAGLTPARLHAVLRPKADAAWHLHELTREEDLAAF
VLFSSASAVLGTAGQANYAAANAFLDALAHHRH-ALGLPATALDWGLWDRPGMTGALTDTDRLRRGGLRPMTTDEALSVLDAALRSPAPRMAAHLDRAAL
RAQ---G----------------------SPDPLLRELLPA------------TVGRR-------TARGASGWARELTGL----TEDERRAAVRRQVRAH
AAAVLGHESLGADRTFRDLGFDSLTSVELRNRLTAGTGLPLSAAVVFDHPTVTALADHLLSLAAG-------
>tr|A0A0M8VVE6|A0A0M8VVE6_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. NRRL WC-3618 GN=ADL01_19130 PE=4 SV=1
-------------------STVGRWMYRESWKPLAGLAP-AAFDGTWWVVAPADEGAHPAAGLEARGARVVRIAVGRDDA------------RREVVAGK
LRELLDGVGHPQGVLSLLALDDSEGS-----VHPTVAAGLEGVLVLLQALGDADVAAPMWAATCGAMTTGRDRLAAPAQAAVWGMGRVAALEQPQRWGGL
VDLPAHADE---RAGLRLADALGRPSGEDQVAVRGSGVFVRRLVRAPLADVSSGRSPEWSSRGTVLVTGGTGALGGHVARWLAGVGAEHLVLTSRRGPDA
PGA------AELRAELEQMGVRVTVVECDAADREALARVLDAIPED--VPLTGVFHTAGVLDDGVLDGLTAERFATVFRPKAQAALNLHELTRDSRLTAF
VLFSSVAGSLGIGGQGNYAAANAFLDAFAEHRR-SLGLPALSLAWGPWAGGGMAVDGGVEQRVRDSGMPPMAPDLAVAAMGALLAAGSAITLADVEWDQY
APTYAM---------------A-------RPCHLFDQLTGPPV-----STEVSTTGP-DRRSAR--GATPSSLADQLAALP----AAERERALLDLVRER
VATVLGYKTVDTTRPFKDLGFDSLTAVELRNLIGAASGLHLPATLVFDHPTPAALVGFLRGEL---------
>tr|M3CU99|M3CU99_9ACTN Modular polyketide synthase (Fragment) OS=Streptomyces gancidicus BKS 13-15 GN=H114_17916 PE=4 SV=1
-----------------------GPHHEIIWTPAQGLPDTARLSGRWLLVRSTLDGDDATVALRAAGADVVTVEQHHLDR------------RTE-LSRR
ITAAAE--APVTGVLSVPAVGGP---------ADDMTAGASATVVLLQALGDARVEAPLWTLTRGAVAAGADPASDPAQAAVWGLGRVAALEHPDRWGGL
VDLPSELDR---RSAERLVALLADSPREDQVAVRADGAFARRLIPAAP-----PAEAAWQPAGTVLVTGGTGALGARVARWAAQQGAERLLLVSRRGAQA
PGA------EALGEDLRRLGADVTFAALDLTDRDAVRELLDAHP------VDAVVHTAGVIEDGVLDGLAPEAFRSVFAAKVTGARHLDELTRDRDLSAF
VLFSSFAGTVGSAGQGNYAAANAVLDALAERRR-AEGLPAKSVAWGPWAGGGMAADAGEGR-QVRGGVGLLDPDQALEALAAQA-GGSASLVADVDWSRF
GAAFTA---------------V-------RPSPLLAEVYDRPA-----ETRT--------------APASTALRDRLAGLT----PEDRRRELLAEVRTR
AAAALGHGQVGAELAFRDLGVDSLIAVELRNTLAAVCGVTLSATVVFDHPTPQALAAHLYDEL---------
>tr|A0A0F4IQV4|A0A0F4IQV4_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. NRRL S-495 GN=VR45_41010 PE=4 SV=1
-------------------RSAESWRYHVVWAPLSVA-PADGLPGRWLALRPEDDAAAVLDTLGEAGADLLPCVVADPGA------------TREQLAVL
LTTTAG-EQPIAGVLSLLSWEERSHP-----DHPDLPGGPALTLALIQALEDTGLDARLWTLTKGTAVLGGERPGHVGQAASAALGRTAALEHPHRRGGL
IDLPEVLDV---RAARRLCAVLAGAADEEQVAVRSTGVHGRRLRPASPASPRVRTRPRWQ--GTVLVTGGTGGVGSHTARWLAGQGAERLLLVGRRGADA
PGT------DALRAELTALGTEVAFAACDVADPAALAVLVADIPAR--YPLSAVFHAAGVLDDGVLDALDPARLAVVLRAKLTAARNLHEATAGLDLSAF
VVFSSVMGVVGNAGQGNYAAANAAVDALVASRR-AVGLPGTSVAWGAWAGPGMLADD-VAARLRDSGMPVMEPETAVTAIGRAL-EDEAVVVADVDWRRF
TTGMGP---------------W--------SAALLDGIPDPAA-----ARPVTTAPS---PARAG-GGSADVLRQRIAVLP----RHDRVRTLTELVRTH
AATVLRHDTVQPGKAFSALGFDSLTAVELRNRLAAATGLALPATVLFDHPTASALADRLLADL---------
>tr|A0A0M8VZL5|A0A0M8VZL5_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. NRRL WC-3618 GN=ADL01_19150 PE=4 SV=1
---------------------------------------------RWLVVLPENAAEHPSEALAQTGAEVVELKLPSAEL------------TRKTLSAQ
LRETAE--AGLAGVVSLLALDESAHD-----TYKAVSVGLAGTVALVQALGDAGVGARLWALTGGAVATGRDRDTNPVQAQMWGLGRVVALEYPDRWGGL
IDLPQAYDA---RAASRFAAVLAGAGDEDQLAVRDTGVFVRRFTPAPVDA-GKGAEPEWAPRGTALITGGTGAIGGHVARWLAREGAEHLVLTSRRGLDA
PGA------VELQAELEELGAEVTIAACDVADWDAVTGLLDGLAAG--RTLRSVFHAAGVGQEQPLDTMTAADIAETLEAKVAGAAHLDAL-LETSLDAF
VLFSSNAGVWGSGSQGAYAAANAHLDALAEQRR-ARGLTATSVAWGLWGGGS-GMAGEAEDALRRLGVTAMAPERAIAALAEAV-YDETLAVADIAWERF
APAFTS---------------V-------RPSPFIGDLPGVRR-----ALAGPITGS-AASGTKG-PVSGSEWAERLAVLP----TAEQERSTLDLVRAQ
AAAVLGHEAVEPGRAFRDLGFDSVTAVEVRNRLAAATGLKLPTTLVFDYPDSRTLAAHLRREA---------
>tr|B9ZUJ6|B9ZUJ6_CHOCO Polyketide synthase OS=Chondromyces crocatus GN=cndA PE=4 SV=1
-------------------DPLHGMFCKVVWQQRPLARSTPSAHGIWLLLADRGGVAEQLRHVLARGERCVLLRSASSTDAAGPQSDALLPTSAEGYKQL
FANMKQEALACRGIVSLWPLDTATPEDSLASLDASLQRSSTRVLDMIQGISRLPAAPRLWFVTGDAEATGVAAASTLTQAPLWGLVRAMAYEHPELQPTC
VDVPSSTAL---AVVEALADELLAGEGERQIRLREGARDVARLVRRPDFRPADPCGARIREDGTYLVSGGLGALGLATADWLVQRGARHLVLVGRGDPSA
---TAQEQIARF----EQAGASVKTARVDVADEAALTGLLTELRT-TMPPLRGVFHSAGVLDDGLLLQQTRERFEGVMRPKALGAWNLHVTTADAPLDVF
VLYSSAAAILGSPGQANYCAANAFLHALARHRR-AAGRPAHCIAWGPWGDVGLAAADERGARLAARGLGSLTPTQGKQALGRVLDQGEAEVVTPFNLRHW
REFYPIAA----------------------NSPLFAEISDAQP-----ERPE---------------RDRAPLSEELRRL----APDARRERLEAHVRDH
LATVTRMARIQSDAPLMNLGLDSLMSLELRNRLEASLRITLPATLMFGHASLGSLAGHLAERM---------
>tr|A0A089VKX9|A0A089VKX9_CHOCO Polyketide synthase OS=Chondromyces crocatus GN=croA PE=4 SV=1
-------------------VRYEDWFYEAQWEPRPRRGVAPSGNAPWILFADQGGVGQALEALLQSGEPCVLVTAASTYERQQADRYAIRPHHPEDLQRV
IEVLGANPSGCGGVVHLWSLDAPHPAEGVSALGKAMELGCVSALHLVQALADKSSRPRLFIVTRGAQPAGESRSVAVAQAPLWGLGRTLSLELQGLWGGL
MDLDP--------------------------------------------EPQGTAPPSLRGDASYLITGGLGDLGLRVAGWMVDRGARHLVLMSRTRLPE
RDASWVEAITAM----EASGATVRHVAVDVADADQMRAFQEARRE-AWPPIQGVVHAAGVARPQSLLDVDDATLWETLRPKVTGAWLLHEMFEDAPLDFF
VLFSSGSTLLSSPGLGSYAAANAFLDALAHHRR-AQGKAASSINWGFWAEVGMAAREQRLGSSA---HQGFRPEEGLEILGGLLGELPVQRVMRVDWQQW
RAHYPSAA----------------------SAPFLSRLVEPVQ-----IQAP---------------AEV--LPDVLRTL----TGWQRRSLLEAFLREQ
LALVLKSARVDEAAPLRSMGVDSLMAIEFRNRLEASLGLVLPATLVWTYPTLSDLATHLATKL---------
>tr|A0A060ZNN9|A0A060ZNN9_9ACTN Short-chain dehydrogenase/reductase SDR OS=Streptomyces iranensis GN=SIRAN1996 PE=4 SV=1
------------------QSGRYDSLFQLDWQPVATSAP-AAAGGSWAVVGPDAGLGEAVGRA------------GGSYAR-------------------
----------YADVPALSALDEGESVPETDGLAARVRESLSAALSSVQSWLGELAASRLVVATCGAVATESEDVADLVQAPVWGLLRSVQTENPGRCLLL
DHDPDHGQEISAVAADAVVRVLAVDAEEPQLAVRGDTVLVPRLSRVAKPAVDLEASARLVSGGTVLVTGASGVLAGVVARHLVDHGVEHLLLASRRGLDA
PGA--AELVAEL----EAAGASVTVAACDVADREAVRELLAGIPAE--APLRGVVHTAGVVDDGVVEGLSDERVQRVLGPKVDAAWHLHELTRDMGLEAF
VLYSSAAATLGAGGQGSYAAANAYLDALAQHRH-AHGLPALSLAWGHIAQERTAG-----------------------LLDAALATERPH-VLSMKVD-L
KAT----------------------------RKRADAVPALMR-GLV-RAPYRK-------V-AAGQQSAEAWKEQMALA----APEQREQLLLDLVLTH
SASVLGHTGIDPDRALKELGFDSLTAVELRNQLSTTTGMRLPATLVFDHPTPLAVAHYLDSQIRG-------
>tr|A0A0E2WWZ6|A0A0E2WWZ6_MYCAV Polyketide synthase (Fragment) OS=Mycobacterium avium subsp. hominissuis 100 GN=MAV100_14020 PE=4 SV=1
------------------ARSGSGELLDVAWSGIEPRDN-PIEAGGELVVSTRGAVGRPGEDV-------------ADLAGAAVWGLVRSAQAEHPYRAR
LRPAGRRALLELPGPPAWRLAAGDARPGAAGVTDLVAVDRRLVTRVPPGWSMVAGIPVVFLAATGGVGMHWAEVFATASRGKWDTLRAMGFDDAHIADTL
DFEQKFGAAPGGEFNDASLRLLRVARAHPGVRYRAFDLMEAGPDRIAAMMTMPDGPA-GLSGGTALITGATGMAGAALARHLVRHRVPHLMLVGRRGEAA
PGM--AELAAEL----RGAGASVSVLSCDVGDRDAVAAMLAQVPAR--YPLRSVFHAAGVLDDAVIASLTPARIDTVLRAKVDGAWNLHELTKDLDLSAF
VVFSSMAGIVGAPGQGNYAAANSFLDALAIHRH-AHGLPALSVAWGMWEEPSAMD-----------------------LLDDALLGEQPL-VVGTRLDRA
ALAQHR----------------------AALPPLLSEL--------A-GRPARR-------M-LTDMVSLTGLRARLAGM----NAEQRQAELVELVCGN
AAAVLGHADVGPGDAFSDLGFDSLTAVELRNRLKIATGLTLSPTLIFDHPTPAALAEHLGGQLAS-------
>tr|Q08QH0|Q08QH0_STIAD Oxidoreductase, short chain dehydrogenase/reductase family OS=Stigmatella aurantiaca (strain DW4/3-1) GN=STIAU_4029 PE=4 SV=1
------------------PQALREWVYEVAWPEKKHASQ-GADTGKWLVLADGRGLGDALATRLREQGACTVLRAGGEASGPGQLSVNPKDPAE---WQR
VLGQLEAEGPFRNVVHLWSLDSGSQLEETGSLPLLVQRLSRGSGQKAKLW----------LVTRGTQAV--KEAVSVAQAPLWGAGRVLALEHPEMWGGL
VDLSPEA---PAHELEALWQELRMPDGEDQIAYRGAKRHVARLVRSDV---TPESPATWRDDGAYLITGGLGALGLQVSRWLVSKGARHLILASRSGLPD
PGQ--WKAVQEL----QSMGASVQVVRCDVGEQAQVASLIEGIRGS--VPLLGIFHAAGVSTHRSWQETDPELFSTVFRPKAAGAWLLHEYTRDMPLSCF
VMFSSASAVWGAQGMAAYAAANHALDALAHLRR-SQGLAATSINWGRWTEGGMAA-----------------------LLGRLAGSKARV-VASVEWSRF
KPLQEA----------------------KRQRPFLENIVT--------AQPVQK-------A-A-AGNARSELLLRLEEA----PSSRRRAILMDHVRVE
VARVLGASRLEPQQGFFQMGMNSLMSIELKKHLETSLRHGLPSTIAFEYPTVEAMTGFLAKEVPA-------
>tr|A0A0C1ZKG5|A0A0C1ZKG5_9DELT Malonyl CoA-acyl carrier protein transacylase OS=Enhygromyxa salina GN=DB30_02224 PE=4 SV=1
------------------RQGLDALVYQLEWRPSRLRLP-RAPPGLWLVLCDRAAFGDALIAALAATGDCVRVEPGAAFTQVSSDHYRVDPARAEDMHAL
FGHVRERGEPCRGIVHGWSLTDAQPLERS-DVAAVVHVLREL---VGQRWPS---PPKLWLVSRGAAPVRDDEAITTAGAPLWGLGRTLAQEHPGVFGGI
VDVDPHATA--QAQAQALIRELRAPDGEVQIAYRDAQRHVVRVTRARVPA-APSTSAQCRVDGCYLITGGLGGLGLHVARELVNCGARRLVLMGRSALPQ
RHT--WAAIQGF----EREGVSVHLAAVDVGDPDQVKAFLDQHRGW--PPIRGVVHLAGVLQDQILLRLDADMLAAVFRAKVVGAWVLHRALASYDLDLF
VLFSSVAAVLGSAGQGNYAAANSYLDALARHRR-ARGLGGHSINWGPWADVGVAA-----------------------SMRSLLASARIT-VMDVDWSRF
ARAHPT----------------------LSASPPIAELVA--------AELAAQ-------Q-SAPTPKPGEAAAAILAL----PIPERGPRIVALLTAH
IALAVGRESLEADRPMVELGLDSLMGIELRARLEAQLGVELPMATLLEGPSIHVLADDLLARLSS-------
>tr|A0A060ZDJ3|A0A060ZDJ3_9ACTN Short-chain dehydrogenase/reductase SDR OS=Streptomyces iranensis GN=SIRAN1038 PE=4 SV=1
--------------------TVDGWRYRVSWKPVPEVAA-GPLSGTWLLAVPASLADSEISQLEKSGARVVPVAVDTD------------ADRDGLARA-
LLAAV-DGESDVRVLSLLALDEEPYAG-----EPVVASGLALTLWLVQAVAGLGMRVRLWCASRGAVSVGRSDRASAAQAQVWGLGGVAALEHPQIWGGL
VDLPETLDE---RAVSRLVGLLSVEGGEDQVAVRGSGVFAKRLTRASAPEAT--DADGWRASGSVLVTGGTGGLGGHVARWLARTGAGHLVLTSRRGMEA
EGA------AELKAELEGLGARVTVVACDAADREALAAVLNGLPR--EFPLTAVVHTAGVLDDGVLDALTVSRAAGVLRPKVDAARNLHELTAGMDLSAF
VLFSSAAGTIGGPGQGSYAAGNAYLDALALRRR-ADGLPATSIAWGAWAGSGMAVDGELEEQMRRGGMAPMNPELAISALQRALDLDEFLLVADATWERL
AAELGG------------------NR----PAPLLAELTETQR-PT--ASPV-----P--ADPAATESAASELRASLEAL----PSAKRQRNLRKLVRQH
VAAVLVHDAIENDRSLTELGFDSLTAVQLRNRLGAITGLDLPTTLAFDYPNLTALAAHLETGMF--------
>tr|A4F5C5|A4F5C5_SORCE Polyketide synthase OS=Sorangium cellulosum GN=spiF PE=4 SV=1
--------------------TVDAWRYRVVWRTLEAPPA-GDVAGRWLIVARAGVAEDVLARLEARGAEVVHLRLGGD------------DARRERTAAR
IREAIGDAGAVRGVLSLAALDDGTRWR-----DASLPAGLALTLGLVQALGDVGVAAPLWLVTRGAVSTGRADLGSATDAMIWGLGRVVGLEHPERWGGL
VDLASGVDA---TALDRLAPFLASRDGEDQLALRPTGIFARRLVRAPLGDTS--PARPYTARGTSLVTGGTGALGAHVARFLVGRGAEHLVLVSRRGEDA
PGA------GALRAELEALGARVTLAACDVADRASVAALLARLDAQ-GDPVRAVVHAGGVVAQATLASTDLDGVRAVIAAKVLGALHLHELLGDRELDAF
VLFASGAGVWGSGQQGAYAAGNAFLDALAEVRR-AAGLTATSIAWGAWAGGGMLADHDAEEHLRRRGLAPMAPALAVVALAGALDHDETITVADIDWARF
APAFAS------------------AR----SRPLLFDLPDARD-AL--EPTS-----E--PAGARAAGEDRALRDALRLL----SDAERAHRLVALVVAE
TAAVLGHSAIDPHKGFFDLGLDSLVAVELVRRLHARTGVKLAATLAFDHPTPDALARHLDAELA--------
>tr|A0A0C2JPT3|A0A0C2JPT3_9ACTN Polyketide synthase OS=Streptomonospora alba GN=LP52_11215 PE=4 SV=1
--------------------LQ-EPRLGGRWLLLDRER----------------------------R---IAEQLRRHG----------------ARVDT
EVLDDA--------------------G-----LPR---ALA----CIQAFADADIDARLWVATCGAVAVGDSEHRHADQAAVWGLGRVAALELPERWGGL
LDLPTGPAE---AHGRRLVGALL-DGAEDQVAIRTAAAYGRRLRPTEPA--K--DPPHWRPRGTALLTGGMGGIGAQVARWLARLGAPRLVLTSRRGADS
PGA------EELAAELRAIGADVELAACDAGDPAGLAAIKKRAAES-GHPVRTVMHMAGAGVLRGLADTDLQEYSETAYAKVAGADALDELFSPDELDEF
VLFSSISAAWGSGDHGAYASANAYLDGLADRRR-GRGLPARSVVWGIWAPRDGMAADAEDQS---RGIPFMDPQTALEGFHRLL-GDGVEVLADVDWERF
APVFTM------------------AR----PSPLLETVPAAQA-ALR-RD-------R--E--QSGEGAEDSLAERLAAM----RPVDRTRTLGDLVRSQ
IAAVLQYEDVDPDRALRELGFDSLTAVDLRNRLGAATGLRLPVTVVFDHPDAAALAAHIGGLLI--------
>tr|A0A0B5FA22|A0A0B5FA22_9ACTN Acyl transferase OS=Streptomyces albus GN=SLNWT_7325 PE=4 SV=1
--------------------TA-DATLGGTWLLAVPEG----------------------------A---VREALEANG----------------AATVL
VEVPDG--------------------G-----LSQ---GLA----LVQALGDRGIDAPLWLLTQGAVATQAAEPLSPAQAAVWGLGRVAALEHPQRWGGM
IDLPGGTDG---RVTTRLCGVLAGYGEEDQLALRSSGVFARRLVRATAP--P--TGAPWTPRGTVLLTGGTGGVGAQIARWLARNGATHLVLTSRRGPQA
PGA------DTLRAELAELGAKVTIAACDVADREALAALVAEVEAE-GPPIRTVMHIAGAGVLVPLADTDLAEFADTAEAKVAGAAHLDALFDKDTLDSF
VLFSSISAVWGSGEHGAYAAANAYLDALAEQRR-SRGLAGTSVVWGIWSPEEGMAANAEEQG---RGIPFMAPKTAIDAFQEVL-RDEVVVVADVDWERF
VPVFTS------------------AR----PSPLLGRVPEVAR-ILA-AA----------ETPDDGGAESSSLRTRLAGM----SAGDRQAALLSLVRTQ
IAAVLGYEAVEVTRAFRELGFDSLSAVDLRNRLGTATGLRLPVTVVFDYPSAAELAGHLGGELF--------
>tr|G2NZJ0|G2NZJ0_STRVO Acyl transferase OS=Streptomyces violaceusniger Tu 4113 GN=Strvi_3797 PE=4 SV=1
--------------------VP-DAALTGTWLLVAPAG----------------------------A---VRDGLETHG----------------ATVVT
VEAA----------------------G-----VPM---GLA----LVQALGDTGVAAPLWLATRGGVSVGGTDVDSPAQAAVWGLGRVAALEHPQRWGGM
IDLPG-TDG---RVTTRLCGALAGLGDEDQLALRPSGVFTRRLVRAAGH--G--SGASWTPEGTVLLTGGTGGVGAQIARRLAQAGAEHLVLTSRRGPEA
PGA------DKLKAELTELGAKVTVAACDVADRAALEALVREVEAE-GPPIRSVLHIAGAGVLVPLADTDLAEFADTAEAKVAGAANLDALFDRDTLDSF
VLFSSISAVWGSGEHGAYAAANAYLDGLAENRR-ARGLTATSVVWGIWSPEEGMAANAEEQG---RGIPFMTPRLAIDAFWQVM-GDEVVVVADVDWERF
VPVFTS------------------AR----PSPLIGQVPDVAR-ILA-AD-------A--DTGADATGESSSLRDRLADL----APADRQAAVLSLVRSQ
IATVLGYEAVDAQRAFRELGFDSLSAVDLRNRLGTATGLRFPVTVVFDYPSAEELAGHIGAELF--------
>tr|Q7WTF0|Q7WTF0_9ACTN NanA6 OS=Streptomyces nanchangensis GN=nanA6 PE=4 SV=1
--------------------TVSSWRYRVGWRHLPDLGP-AAVAGPWLLVVPPKGA-DACERLTADGGEVRRLVTDGR------------A-DVAELAAS
LRALYAEGPSPAGVLSLLPLDERPHEA-----FPAVTGGVTGTHVLLRALLDAELDAPLWCATRGAVAVDDDEAEAPAQAQVWGLGRVAALEHPTAWGGL
VDLPASVAD---LAPDLLCAVLAGRNGEDQVALRPAGAFGRRLLPAPLDAQA--QERAWTPRDGVLVTGGVAGAAALVARWLAADGTKHIVLLAPDGPAA
PGG------AELVAELAELGAEATVVDGVPSEPTTRQELADRLAAS-GLRVRTVVHAGAPGDWAPLAELTPDELAEALSDAMGGADRLAELCGLEPDDPV
VVFSSIAAVWGGGGHGARAAADAYLDAWARRRQ-AAGGHVARLAWGVWDGSED-----PEARAERQGLLALHPTPALAALRRTLSRSDHAVIADVHWDRF
VPLFTM------------------AR----ASRLFDEIPAARR-AW--QAAL-----D--SSDDESSESLTALRDRLAAQ----SPQARTGTLLALVRAH
VAGALRYESVDPEQPFKELGFDSLAAVEFRNRLRGAIGLTLPATLVFDYPTPTALAGYLVSQVL--------
>tr|A0A0N1JVN7|A0A0N1JVN7_9ACTN Beta-ketoacyl synthase (Fragment) OS=Streptomyces chattanoogensis GN=ADL29_38580 PE=4 SV=1
--------------------TVDGWRQQITFTPLTRTPS-HTPAGTHLAVIPAGHEQDPVLALGPDT---VRLT--AP------------GTDRAALADL
LRQQAAEGPQFTTVVSLLALAAHPAHH-----PAHAPEALALTTTLIQALGDADLAAPLWCVTRGAVAAAPGEPSGPAQAAVWGLGRVAALEYPQRWGGL
IDLPGTLDD---RSAARLADVLAAPGGEDQIAIRPSAVLGRRLVPVPAG--R--STREWNPTGTVLITGGTGALGTHVARELAGAGAPHLLLLSRRGPDA
PGA------DALRAELTALGADVTLTACDAADRDALAKVLADIPE--TAPLTGIVHTAGVIDDGVLDSLTPDRFEDVFRAKAASALALHDLTKDLDLAVF
ALFSSSSGAVGNAGQANYAAANACLDALAEQRR-AQGLAATSLAWGVWGGGGMAADQRAADVARRTGIRPLDPDLAVVALRRAVMG-RTEVVADIARDRF
VRSFTA------------------VR----PSPLLGEPAVDAG-HP--A-----------AGDTGEDTTGDALREKLTGL----PPAKRTEAVRDLVRTR
AAAVLGHDAVAADRAFRDLGFDSLSAVELRNQLGAATGLNLTATLVFDHPNPAALAAHLLSLLV--------
>tr|A0A0M8QC85|A0A0M8QC85_9ACTN Beta-ketoacyl synthase (Fragment) OS=Streptomyces caelestis GN=ADK41_37290 PE=4 SV=1
--------------------TVDGWRQRIAWRPLNRSGP-GAPAGAWLAVLPAGHADDPVLRLGPAT---VRLE--AD------------RADRADLAVR
LRRLQEDGHPFTGVVSLLALAEGYDPQ-----APGTPRGATLTTALLQALGDARVDAPLWCLTRGAVAVSPGESPAPLQAAVHGLGRVAALEYPHRWGGT
VDLPETLDA---RSAERLADVLADPGGEDQLAVRPAAVFGRRLAAVRPG-----APRDWQPTGTVLITGGTGALGAHVARRLAGAGARHLVLLSRGGPDA
PGA------GKLRAELAELGAEATLIACDTADRDALAAVLADIPR--HAPLTGVVHTAGVLDDGVLDGLTPERFETVFHAKVTGALLLDELTRGHDLDVF
ALFSSASAAVGNPGQGNYAAANAVLDALAERRR-ADGLPATSVAYGAWGGDGMAGDGRAAALAQRTGIRPLDPDLAVLALRQAVTS-DVAVVADVDPERF
VRAFTT------------------VR----PSALLTEMPAHAA-LT--A-TA-----A--AAGHDADRAVSDLRDRLARL----PGNRRLGTVLTLVRER
AADVLGHDLVGPDRAFRDLGFDSLGAVELRNQLGAATGLTLSATLVFDHPTPAALAEHILGELL--------
>tr|Q79ZC6|Q79ZC6_STRAW Modular polyketide synthase OS=Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / 
--------------------CPAGEAAPAVWPPRGAEPF-HGLRAAWTVRLPQELHEFASVHTGATA---LRVTLTPAG----------------ANAVS
LYAADGTGAPVVTVGSLLSLTWTPVPG-----HPAVARERAARAWVSEDLDERLAPVPLVVVTRDAVGTSADDPTGLGSAPLWGLVRSVQSENPGRFV-L
LDTDGDPSG---RSV---PGAV--ASGEPEIALRGGSALVPRLSRMAVTELT--GLDALDPSRTVLVTGATGGLGTLVAGHLAEHGVRHLLLLSRRGPEA
EGA------EELVGRLEKLGATVTLVACDAADREALAAVLAGIP-A-AHPLTAVVHCAGTAENALLAALTPELIDRVFRAKVDAAVHLHELTEGLDLSAF
VLFSSIAGTLGGTGQGNYAAANTFLDALARHRR-GRGLPATSLGWGLWAAERGMGGGTDAAGTPMRGVSALPSD--------------GLALFDLGWRCA
EPVVFP------------------AR----LNAAAGSLPPVLR-GLF-RGPAR----R--TAEAGGQDSGAQLRRRLAEL----MPVERQETLLALVRDR
IAAVLGHDRIETDRPFRDLGFTSLTAVELRNRLNAATGLRLPVSLVFDYPTLGELVELLAGKLV--------
>tr|Q0ILC8|Q0ILC8_9ACTN NlmA5 OS=Streptomyces nanchangensis GN=nlmA5 PE=4 SV=1
--------------------CPAGKAEPADWPPRGAERF-RGLRAVWSIELPQELHEFASLQTGATA---LRVALSPAG----------------KSAVS
LRAVDGTGTPVVSIGSLLSMVWTPVPE-----LPALTRERAARTWVSEELDERLASIPLVVTTTDAVGISADDRAGLGSAPLWGLVRSIQSENPGRLV-L
LDTDGSVSG---RAV---RAAV--ASGEAQLALRDGVALMPRLNRPPAADVT--ELDALDPSGTVLVTGATGGIGALVATRLAKHGVHHLLLLSRQGPDA
EGA------GELVHDLEELGATVTLVACDVSDRAALAAVLDGVS-A-GHPLTAVVHCAGTAENALLASLAPELIDRVFRAKVDAAVHLHELTAELDLSAF
VLFSSIAGTLGGTGQGNYAAANTFLDSLAQYRR-RNGLAATSLGWGLWATERGMDSHAEGAGSPMGGVSAMPAD--------------GLALFDLGWRRA
EPVVFP------------------VR----LNAAAGSLPPVLR-GLV-RVPAQ----R--SAQTGSQAPESQLRHRLAEM----GPAERQETLLALVRDR
IAAVLGHDQIETDRPFRDLGFTSLTAVELRNRLNAATGLRLPVSLVFDYPTLGALVALLVARLA--------
>tr|D9WQ84|D9WQ84_9ACTN Modular polyketide synthase OS=Streptomyces himastatinicus ATCC 53653 GN=SSOG_05758 PE=4 SV=1
--------------------AADATFDLAAWPPTDADEF-QGLEAAWRIRLPEGAEAFASLHVGASA---LRVRLAGT------------TTGT--VSLQ
L--ADVTGAPVASVEALFSLTWTPLPA-----APHAPNGAAAASPARPALEDRGLGAEPRVSGRGGVGESPSPAANLAHAAVRGLVRSAQAENPDRLV--
-LVDTDAED---TSLKTL--ATAVATGEPQVAVRNGEILAPRLARTATT--A--EANAWNPDGTVLLTGASGTLGALFARHLVARGVRHLLLVSRRGDQA
PGA------ADLTTELTDLGATVHWSACDVADRTALAETLATVPT--ARPLTAVVHTAGVLDDGVIGSLTPDRLSTVLRPKADAAWNLHDLTQHADLKAF
IVFSSAAGVFGGAGQGNYAAANAFLDALAQHRA-ANGLPATSLAWGLWAVAGGMGGEDETERIRRGGIGVLTADTGLELFDAATTASELLVPMPLDMAAL
RAQAG-------------------VG----MLPPLFRGLVRAA-PA--RRAA-----E--SAATAGAGGADELRARLAGL----SEPERDEAVLELVCTQ
VAAVLGYETVDPARSFSEVGFDSLTAVELRNRLNATTGVRLPATLVFDYPTPNALVQYLRGEIL--------
>tr|D7F1M9|D7F1M9_9ACTN Polyketide synthase OS=Streptomyces longisporoflavus GN=tsnAV PE=4 SV=1
-------------------------RYRLRWDPVPDPVD-HSAPGNWLAVLPPALATD-ITGLTAHGHRVVAFVADPDG----------EPSPAELLRAQ
LAAGAPDGTPFTGVLSLLALDERPHHD-----HPAVSVGTALTAALVQGVAAAARPVPVWGLTRGAVAVEASDG-RPEQAPVWAVLQAAAAELPTWSGGL
IDLPGTLDD---DAGRRLAAFLRG-SAEQQVALRPAGLLARRLSPLPTD-----GSDVWQPGGTVLVTGTDTPYGAHAARWLAAHGAEHLVLLA------
----------EAPTGLAETGVGLTLWPYDPTDHDALAALLA------DTPVTAVIHTTGAAHTDP-------------RTALATAHHLDRLTRDRDLAAF
VVFSDLSGTLGLPGTGAQAPLHARLEALTDARR-AAGLPAATLAFGPLTE-----------HLAPLGVRPLAPKPAMDVLGRIP-RGATTVVADIDWARF
TAEPN-------------------NA----PLALLREIPGART-AAA-HDGT-----G--PAGADRDAEGERLRARLAEA----SDDEERAVLLDLVRDC
AADILGHDQVGPEDNLAEIGFSSFSALQLCTRLNAATQLTMPTVVVYDHPTPAGLALHMHGRLA--------
>tr|A0A0B6VLR1|A0A0B6VLR1_9ACTN Putative type I polyketide synthase OS=Streptomyces versipellis GN=vstA5 PE=4 SV=1
-------------------------RYEWRWEPARVPAA-AGPPGTWLVVAAPGALEEEVVALAARGGRVVPLVVDPE------------SSGGGESVSV
LRAGLRARPEVDGVLSLLALSERRHPA-----FSAVTAGLAATVELLDALDDMGVRAPVWLATRGAVSVSSADVAGPAAAQVWGLGQGPADGGAGRWTGL
VDLPGVPDG---RVADRLVDVLAGSRADDRVAVRGPGVFVRRLVRAPGEGGA-----GAELGGTALVSGAASVLGGQVARWLAGRGARRLLLAGAREAEA
PEV------VKLSAELGDLGAEVTVAVCDPADRAALAGVLAGVPD--GAPLTAVVHVGAAGEAGGVRA--LERMDRALVRDVAAVAHLDELTGGADLRVF
TVFSSPSGLPGYGG---GSVAEACVEALVRGRR-ARGLPGLSVLSGPLEE-------EPTEQVPGVGGV---PASAVPVLAGAAERAQPVVVADVDWPSL
VALLGA------------------EG----GRPFE-KVPEVRR-LL--RGGP-----D---------AGAGRVSARLDGV----PAEERMGVLLDIIRTD
VAELLGHEGIGADEDFTDLGLSSFSALELTNRLRA-AGVEVTPNVIFEYATAARLARRLVDGAG--------
>tr|A0A0M2GG91|A0A0M2GG91_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces variegatus GN=UK15_38785 PE=4 SV=1
---------------------HGGSLFRVDWTPLPMAP-SAAAEGSWAVLDDSAGLATLLS---GEGAAVS-S-----Y---------------RDLAEL
AA---VDGRVPDVVVAAVPDRSGALSAGGEGLPEPVHETARWTLDLVREWLSHESGSRLILVTRGAVAVEGEQVPDPAAAATWGLVRSAQSEHPERF-VL
ADLDAAPAPG--T-AIALAAVL--AAGEPQAAVRSGAVRVPRLTRDVSSTPA--APPVWDAEGTVLVTGGTGALGALVARHLVAHGVRHLLLTSRRGLAA
PG--AAELRDE----LTGRGARVTVAACDVADRDALARTLAEVPAE--HPLRAVVHTAGVLDDGVLEALSPERVSRVLRPKADGAWHLHTLTRHLDLSAF
VLFSSAAGVLGGPGQANYAAANAFLDALAAHRH-AAGLPARSLAWGLWDQDGMAGALDDLERLRRSGMKPLSAEQGMALFDAACRAGDPVLVLRLDTSAL
PVEP-A------------------AA----VPAPLRGL---VRR------PVRK-------RAGTG-GGALSLKGRLVAL----AEADRTRTLLELVRTE
VAAVLGHAEIEPSRAFGELGFDSLSAVELRNRLTAATELRLPATLIFDHPTPAALANRLRVELL--------
>tr|A0A0M2GB82|A0A0M2GB82_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces variegatus GN=UK15_38890 PE=4 SV=1
---------------------RHDALFRVEWTALPATEELSGPTGDWVELVAEQTASGVPA---GGGER---------Y---------------ADLGAL
AAAVDAGRPAPEAVVHRVVPG-----GDVGSLADVGYDVARAVLDLVQAWLADNTASRLVLVTSGAVAASDGDVRAPEAAAVWGLVRSAQSEHPGRL-ML
VDADPATPAA--T---LPTAAA--RSAEPQLAVRGADLLIPRLARAPHDEAV--TGLVPDPDGTVLLTGATGALGGLFARHLVTHGVRHLLLASRSGARA
EG--APELEAE----LTALGATVTLVACDVADRDAVAALLAGIPAQ--HPLTAVVHAAGVLDDGLIDTLTPQRLDRVFRPKVHGAVHLHELTRDLNLSAF
VLFSSVSGVVGSPGQANYAAANAFLDALARHRR-AQGLPATSLAWGLWEGTGMTGTLDDLARMRRAGMIGLTAEEGLALFDAACAGADAAPVVRLALSAL
RRT---------------------GT----PSPLLRGL---VRG------PARR-------TADTA-GPAGAFADRLARL----PAAERARLVLDLVRAE
TAAALAFDEVPPAKAFKELGFDSLTAVELRNRLNTATGLRLPATLVFDYPTPTTLADFLTAELL--------
>tr|D9WB21|D9WB21_9ACTN Modular polyketide synthase OS=Streptomyces himastatinicus ATCC 53653 GN=SSOG_00527 PE=4 SV=1
---------------------GSDSLFRIDWAPLPSGSVTG--VAAVAVVGAEEALAPALR---DAGTEVR-V-----Y---------------ADLAAL
SA---ADGSVPDVVLAALPGA-----RSRNEVVDTVHASAASALELVQDWLVEETRSRLVMVTQGAVTARADD---LAVASVWGLVRSAQSEHPDRI-TL
LDLDDGSVSG--A---VLSRAL--AQPEPELTVRQGRVLVPRLTRMPVPEL---RAASWEPRGTVLITGGTGGLGAVVARHLAAHGVRDLLLLSRRGMAS
PG--AEALVAE----LAGLGARAEVVACDVADREALAKVLG----G--HEVSAVVHSAGMLDDGVIGALTPERVDAVLRPKADAAWHLHELTRDLDLSAF
VVFSSAAGTFGSAGQGSYAAGNAFLDALVRYRR-DRGLPGVSLAWGAWDQDGMVGELSDRERMHRSGFPPLSVEQGVALFDAAVGAGEPVVLVRVDLSVL
RAR---------------------GE----VSPLLRGL---IRT------PFRR-------AAVTG------LAQRLSGL----GEVEQGEVLLDLVRSQ
VAMVLGHAAIDPGRSFRDLGFDSLMAVELRNGLGAATGLRLPATLVFDYPTAQALADHLFDELL--------
>tr|A0A086GIC6|A0A086GIC6_STRSC Uncharacterized protein (Fragment) OS=Streptomyces scabiei GN=IQ62_43715 PE=4 SV=1
---------------------SGSDLYTVTWIPADAPSLEPASTTR--HTGADDLLAAAST---A-----------------------------------
-----SDTPYAELVVVPWQTP-----DPETALVPGVHDATARALILLRHWLTDAVGSRLLVLTRGAVAAHDETVTDLPAAAVRGLLKSAASENPGRF-LL
LDTDVTPTDD------QLADAV--RRGHDELVLRDGKLFAPSLNRVRDTPPP--AGVVFPTDRTVLVTGGTGAVGAAVVRHLVTHGVRRLLLVTRRGPQT
PG--AAELVDE----LAAHGARTTVVSCDAADREALADVIDALPPE--YPIGAVVHAAGVLDDGVITSLTPVHLTRVLRPKADAAVNLHELTRDLGLSAF
VMFSSAAATLSSPGQGNYVAANAFLDAYAARLR-ADGHPAVSIAWGLWETSAMTRGLATHKRAARSGVDALPTGDALVLFDRALTHTEGTPLLCLDRTAL
RRA--A------------------DR----LPPLLRSL---TGR------PALR-------EAAAR-PA--ASPLGLSHL----PESRRRDAVADLVRTT
LAAVLGHTPIRPDTPFTQLGLDSLTALELRNSLSHATGTTLPATLVFDHPTPEAVVDLLLAGLT--------
>tr|A0A0F5ABA6|A0A0F5ABA6_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. MUSC164 GN=VT50_17780 PE=4 SV=1
---------------------YHDSLFRLEWAPVPSPSAPA--AVRWAVVGEQAALVDALE---SIGAECA-V-----F---------------PDLSGL
AAVVASGSPRPDVVLLPLTGP-----TGDGHVAEDARLAAHEALDTAQSWLAEEAGARLAFVTRGAVATSDAAVADLPHAPVWGLIRTAQTENPDRF-LL
LDLDGEGAP-----AGALMAAA--AGGEPQLAVRAGALHAPRLARVATQGEQ--GLPEFDPDGTVLITGATGVLGGQLARHLVARGVRHLLLNSRRGQRA
QG--MPELVDE----LTALGAEVSVAACDVADRSALSLLLAEVDPE--HPLAAVIHTAGVLDDGLLPALTPERIDTVFRPKVDAALNLHELTADLGLRAF
VLFSSAAGTFGAPGQANYAAANTFLDALAAHRR-SAGLPALSLAWGLWEQSAMTGGMADVARMERSGMAPLTSRDGLELFDTAGSVGEAVLVLHLDVAPL
-REA-E------------------GA----LPAVFRGL---VRA------PARR-------RTVSA-GAGPSLARRLAGL----AEPEREKAVLDLVLGQ
AAAVLGFEAVGAARGFLEQGFDSLTAVELRNRLGAASGLRLPPTLLFDHPTPELVARQLLAQLA--------
>tr|A0A0F5A7C0|A0A0F5A7C0_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. MUSC164 GN=VT50_27220 PE=4 SV=1
----------------------DDSLFELDWTTIEAGPREPV----TAVVGSAAGL--------------------------------------------
--S--HVERAPDVVVYRVDGA-----------PAEVTDAVSATLAVLQQWIADDVSSRMVVVTRNAVSCPGDQRTDLVGAAVTGLVRSAQSEHPDRI-VL
VDVGDTDDTD--D-IAALGWTS--GIGEPQLAIRCGRVLVPRLRKTTSPPS---AEPGWAGDGTVVVTGATGGLGALVTRHLVDHGVRRLLLLSRSGMAA
PG--VEALVAE----LGERGADVRVAACDVADRDALAGVLAALPPG--AEVTGIVHAAGVLDDGVLASLTPERVAGVLAPKAVGAWHLHELTRDMPVRAF
VLFSSIGGVLGSAGQANYAAANAFLDGLAHHRH-QLGLPATSLAWGLWAGQGMGAGP-GPKRPVRGGVAPLSEAEGLALFDLLATADRPFVVARLQPGEL
RDRD-T------------------GY----LPAVLRRL---VRT------APRR-------RTVRG-QE---APADFAAL----DDAARARALTDLVRDR
VATVLGYGEVALEKGYLDMGFDSLTALELRNDLSAAVGLRLPATLLFDHPTPATTVRRLGELL---------
>tr|A0A0A0NT19|A0A0A0NT19_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces rapamycinicus NRRL 5491 GN=M271_46380 PE=4 SV=1
---------------------DHESLYRLRWDAMPPLGDPS--TARCAVIGEEDGLAVALR---SAGWQVR-T-----H---------------PDLGAL
ARSGAEGESLPEWVLLASATG-----TG-GDTRQGLRGAAHQALERVQEWLAEEADSRLVITTRGAVATTTEGVDDLAGAAVWGLVRSAQAEHPGRL-LL
LDADGPMGL----GSVPLAAAL--ASGEPQLAVRGGRVLAARLVRAEGT--G--ASATWDPEGTVLITGASGTLGGLLARHLVAHGVRHLVLLSRRGSAA
EG--AAELADE----LTSAGASVTWAACDVADRDALSAVLSDIPAA--RPLKGVVHAAAVLDDGVIASLTPERLDTVLRPKAEAALALHELTAGLDLSAF
VAFSSVAGMFGAAGQGNYAAANAFLDALVSQRR-AHGLPGLSLAWGLWEESGMTEGLADRRRMDQVGISALSSTEGLALFDAACAGG-PVIAARLNTTVW
-RSG-F------------------VE----VPHVMREL---VRV------PARR-------VTAESTGAAEALRARLAGA----SYAEGERLVLDTVRRN
VAAVLGHETVEPGRAFKDFGFDSLTAVELRNRLGTVTGLRLTATLVFDHPTPTALAQHLHHELT--------
>tr|A0A014M3I0|A0A014M3I0_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. PRh5 GN=Z951_46895 PE=4 SV=1
---------------------VHRSLFQLNWSLLPGAGTVE--SAVADVT--------PLD---GVDWHDI-A-----A-----------------FG--
EAIGAEGAVPPAVVCVPPYV-------P-TTDGDAIRDVIHRALELVRGWLAEEAGSRLVIATHGAVTVEDEAVVDLAAAAVWGLVRTAQTEHPDRF-VL
VDLDGGDREP--EHLSLLSAAV--ASGEPQVAVRGGRLLAPRLGRVRPAETV--RSVVWDPEGTVLVTGATGTLGGLVARHLVAHGVRHLLLVSRRGADA
PG--ARALEDD----LVAAGASVSWAACDVADRDALTAAVKGVSDP--HPLRGVVHTAGVLDDGVIASLTPERVDAVLRPKMDAAITLHELTEAVDLSAF
VVFSSAAGTFGTAGQANYAAANAFLDALIRHRR-TSGLPGLSLAWGLWDEDGMAGGLADLRRMGRAGVDGLSPEEGLALFDAGCAGLPVVI-MRLDPAK-
---A-D------------------GE----VPHIMREL---VRP------MARR-------AAAEGTGD---LRERLAAS----SEEDGERLVLDLVRRC
VATVLGHAAVEPGRAFKDFGFDSLTAVELRNRLGTATGLRLTATLVFDYPNPIALARHLHQELT--------
>tr|A0A081E987|A0A081E987_STRFR Uncharacterized protein OS=Streptomyces fradiae GN=SFRA_32405 PE=4 SV=1
---------------------GERSLYRVEWQPRLLPAGPR----SWAVLGPDADLG--DQ---PDGGPTA-L-----Y---------------PEVRAL
RKALAAGAPRPEAVVLPVLSG-----A--GATPESVRQTTERCLTALQDWLDAEVDTPLIVLTRGAVAAVGEEIGDLACAGVWGLVRSARSEHPGRF-AL
VDTDGHPDDR--TALPLALRAV--LDGAGQLSLRAGTARTPVLLRAGT---Q--RGPAFDPAGTVLVTGATGTLGRLLARHLAAHGVRHLLLLSRGGRAA
EG--ADELAAE----LAGLEAEPCFAACDAADREALARVLAEVPAD--RPLTGVIHAAGVLDDGTLDALTPERIGTVMRPKADAALNLHELTRTSPLSVF
AVFSGAAGILGRPGQANYAAANTFLDALAQHRR-AHGLPAVSLAWGLWGGTGMTGHLSDLRRMRRSGIAPMTHDQGLALFDRALAAEDPLLVMRLDLAAL
VREG-P------------------DA----VPGPLLGL---LPA------RARQ-------AAAPVRPAGEGTAERLAGL----GEEARLRELVRLVRAE
VSGVLGYDAVEPGRPFKDLGFDSLTAVELRNRLGAATGLRLPTALVFDRPTSQAVAEYLAAELA--------
>tr|I0J6Y4|I0J6Y4_SORCE Non-ribosomal peptide synthetase/polyketide synthase OS=Sorangium cellulosum GN=pelA PE=4 SV=1
-------------------DALEECLHEVAWRPAEPLAEPLPRGGAWVVLADQGGVGAALHARLALGQRCVRVFAGAGYERIEPDLYRIHPARAADYQRL
LREVFGEEGRCLGAVHLFGLDAAPAPATPETLSADLTRGSVSAAHLTQAIVRHRDAPRLFLVTRGAQATLGGARVSAAQAPIWGLGKTIALEHPGLKCTR
IDLDPAATD---ADAALLARELGARDREDQIALRGEGRYLGRVVRGRFEA-GAGTPFALRSDVSYLVTGGLGRLGLALSRWMVEAGARHLVLVGRRGPGD
AAR---GGLEAL----QAAGARVLVAQADVAARGDVARVLSTIELE-MPPLGGVIHAAGVADDHPLLDLDEERFRRVFAPKALGAWNLHALTEGRPLDFF
VMCSSSASLFGAPGEASSSAADAFLDALAQERH-AMGLPAMSVQWGAFAEGGPEATAARRERRPRRGVAPLTLEQGLEALRRLFARPRAAVVVRFDARQW
MELYPGA----------------------ASLPLFVEL------------A-------REAASVGG-QEAPQIRGTLGRA----APRERPFVLERHVIEQ
VSRVLRVARVDAHAPFKDLGLDSMMSLDVRNRLEASLGVQFSATILFTYPSTAALARYLLDRMDI-------
>tr|A0A0C5FUT4|A0A0C5FUT4_9ACTN Uncharacterized protein OS=Streptomyces cyaneogriseus subsp. noncyanogenus GN=TU94_22470 PE=4 SV=1
-------------------ATTRATLEHRAVVLAAPWVEVRPADALWQRVDVLWAVMVSLAALWSFAAACVAGEDGARVVAVAPVDYASHSAQDALADDL
LRELADIAPRSSGRLDTVGLDAGYDVARPVAVVGSLRREDLADLATVLTLAAWRTEAPLWLLTRGAAGVTDEEAVRPEAAQVWALGQVAGLELAGAWGGL
VDVPEEWDE---AVATGLADVLAAGEGEDQVAVRASG-VFGRRLVRAPLA-GTAPSRSWSPRGTVLVTGGTGGLGAHLARWLAKEGAERLLLLSRSGERA
EGA---TELREI----EASGTAVELVACDVTDRDALAGVIGAVPAE--QPLTAVFHTAGAAAHGPLTELDPAALDEQLAARVAGARHLDELTAGVELDTF
AVFSSGAAVWGSAGNGANAAAGGYLDGLARRRR-ARGLAAVSVSFSGWQGTALARGAQ----LSRRGVRLLPPELAGQALRQVLETDETSVVADMDWSLF
APGYTLA----------------------RRRPLIEDI------------P-------EVEAAQDG-SAGAELRARLAGL----TEAERRSHLLGLVRGE
AAQVLHAAEVTPARPFRDLGFDSLTAMELRNRLNRATGLRLPATLVFDHPSPQRITEHVLAELGK-------
>tr|A0A014MT90|A0A014MT90_9ACTN Uncharacterized protein OS=Streptomyces sp. PRh5 GN=Z951_28760 PE=4 SV=1
------------------RATVDSWRYRITWSPMAVEGRTAPLSGTWWVAVPEGADGARVAALDRRGARVVPLTV--------------ATTGRDALAER
LRHEAVTGGTPAGVLSLLALDDGPHPE-----HTALSTGLALNVGLIQALGDAGIAAPLWLATTGAVSVSGSPLGSPAQAATWGLGRVVALEHPQRWGGL
VDLPENLDE---RTADRLCAALGDSGPEDQLALRDAGVFVRRLVRAPLRTP---GRESWKPHGTVLITGGTGGLGAQVARWLARSGAEHLVLTSRRGMAA
PG--AAGLRDELIA-LGEGGVRVTVAACDVRDRDEVAALLRRITTG-GDPVHAVFHAAGVVEFSQLADSTVADFAEMADGKVLGAAHLDALLDQDHLEAF
VLFSSIAATWGSGGQSAYAAANAHLDALAEHRE-ARGLPATSVAWGPWADHGMIEHGEVAEHLSRRGLPAMAPELAVAALSEALHTGETSVLADVRWDRF
VPGF------------------TAARPRPLIGELPE-------------VRDALAT-TAAPDTTGPDDVADTFLASLADL----TGEDLDRALRDLVHAQ
AAAVLGHDAVAGGRPFKELGFDSLTAVELRNRLAAVTGLDLPATLVFDYPAPAPLAEYLRGELP--------
>tr|D9W7F8|D9W7F8_9ACTN Modular polyketide synthase (Fragment) OS=Streptomyces himastatinicus ATCC 53653 GN=SSOG_08452 PE=4 SV=1
------------------HSTIDSWRYRIAWDRLHDTVGAPALTGTWLLLVPSGAEHPVAAQLDAHGAARETLTV--------------DTAHREALAQQ
LT---DVRTAPVGVLSLLALEESHHPD-----HPAVPTGLAATMALVQALDELGWPAALWCLTQGAVAAAPSALPHPHQAQIWGFGRVAALEYPQLWGGL
IDLPDTLDA---RTPGRIAG--TPGQPEDQVAIRS-AVLGRRLEHAPATDA---LAVPWQPTGTTLITGGTGGLGAHLARWLARNGAPHLHLISRAGPDA
PG--ATELTQELTE-LG---TTVTITVCDVSDPTALHHLIDTIP-A-EHPLTTVIHAAGIAENTSLGEIDLPHINAVLQPKALAATHLHELTKDHDLSAF
VLFSSGAASWGGSRQAAYAAANTYLDALAEHRR-LQGLPATSIAWAPWGDAGMAADEAVIEYYNRRGMNPLDPDLAVASLQHALDHDDITTVADIDWEKF
PVSF------------------TAQRPSPLLTRLMP-------------TPSSG---ADAPDSTAA---ISSLQQQLAGS----TPAQQHQLLLHHLQSH
AAAILGYHSIPPAQPFQELGFDSLTAVEFGNRLTATTGIDLPPTLIFDHPTTNQLADVLRGRLV--------
>tr|A0A0A8ELH0|A0A0A8ELH0_9ACTN Beta-ketoacyl synthase OS=Streptomyces sp. 769 GN=GZL_03711 PE=4 SV=1
------------------RVTVGSNG-ATTWTRHASGQPVPVVPGAWDDLAAAGGYGPALRALHAAGS--GAVRV--------------RIAGRDAVSLT
VSDQATVPTSPGGLPELVFVAASGHPG-----ASVAHAAVHRALAMVQELEERFASSRLVVLTRGAVATGADDVADLGGAAVWGLLRAAQSEHPGRFV-L
VDLD----E---HAASRGL--LAAASGEPQLAVRQGALYAPRLARVPPAEG---IRRPLDPAGTVLITGATGALGGHVARHLVAHGVRHLLLTSRRGEAA
AG--AAELVSELAE-LG---ASARMAACDVADRDELAALLDGVP-E-AHPLTAVVHAAGVLDDGVLESLTPERIDAVLRPKVDAALHLHELTRDLDLAGF
VLFSSASATFGSAGQGNYAAANAFLDALAVRRR-ALGLPAVALAWGPWAD-GGMADEADRARMARLGMVPLSADQGLALLDAAQSVDEAVVPIRLDTAAL
RT---------------------KAGGVPALRGLIR----------------------SSARPTVSTTEGPSLRERLAAL----TDAEQDRLLLDLVRTH
SAAALGHHAVDAGRGFLELGFDSLTAVELRNGLSAATGLRLPATLLFDYPTPSALRDHLRAELA--------
>tr|A0A0A8EKF4|A0A0A8EKF4_9ACTN Beta-ketoacyl synthase OS=Streptomyces sp. 769 GN=GZL_03708 PE=4 SV=1
------------------RVTVGSRGEDQPWTRHASGAPTSGLGGVWQRLVESGGYGPALRALHGHGA--SALRV--------------RISGQDAVSVL
VADGAELRTGPTDVPELVLVT--------------VRAATHRALELVQRLDERFGASRLVLMTRGAVATGADELSDLAGAAVWGLIRSAQSEHPDRFV-L
VDTD----G---RAVSHQA--LALATGEPQLAVRKGAVLGARLARVQPVQD---AAPKLDPAGTALVTGATGTLGRLVSRHLVAYGVRRLLLTSRRGEAA
PG--ARELVAELAE-LG---AEARVVACDVADRDALAALLAEVP-A-EHPLTAVVHTAGVLDDGVLEGLTPERIDTVLRPKVDAALNLHELTGDTDLAMF
ALFSSAAATMGSAGQANYAAANAFLDALARHRA-DQGRPAVSLAWGLWAQAGGMAGDTDLTRMQRSGVGGLTPELGLALFDAAHTLAEPAVPISLDIDAV
R------------------------APVPALRGLIR----------------------GATRPSAVATEGPSLRERLAGL----TVAEREAVLLDVVRAH
AATVLGHQAVEEDKTFGDLGFDSLTAVELRNGLTAATGLRLPATLIFDYPTPAALADYLLTELP--------
>tr|B2HJA3|B2HJA3_MYCMM Polyketide synthase PKS OS=Mycobacterium marinum (strain ATCC BAA-535 / M) GN=MMAR_0101 PE=4 SV=1
------------------AGAPDDKLLEVAWSPIALNDRTDVPVMLWDDHRDDDGH--------------------------------------------
---------GA-GTVVIWESCCAAD----DDVVRSAYAATHAALAVLQSWLSGDRPGTLVIVTHGGVALTDEGVKDLAAAAVWGLVRSAQSEHPG-RIVL
IDTDSAPTDP---EVLMDLA-NLAGRGEPQLLVSGGAVYGARLAPIPPALSAAELASVLDPAGTVLITGGTGMAGGVLARHVVGGGVRHVVLASRQGEQA
PGV--AELVSE----LSAAGAEVLVLACDVADRDAVAQMMEQVRR-RCPPLTGVIHAAGVLDDTVIASLTPDRMNPVLRAKVDGAWHLHQLTRGLGLSMF
VLCSSIAGVMGSPGQGNYAAANTFLDALAAHRR-ATGLAGLSVQWGLWEQTSAMTGHLDLARIRRSGLAPMSVGQAVELFDAAVLLDRSTVVACLDRNAL
ASPAVSA----------------------ELPMLF-------HSLL-PR-PS------RRVINKDATTHESGLAQRLQAL----SPHQQHQLLVETVRNQ
AAVVLGRQDIDPECTFQDLGLDSLTAVELRNRLKAASGLSLSPTLIFDYPTPATLARHLAQQLIGTGT----
>tr|J1ZM59|J1ZM59_9ACTN AMP-dependent synthetase and ligase OS=Streptomyces auratus AGR0001 GN=SU9_33553 PE=4 SV=1
------------------AAAQQDSLFQVEWTEIPAGSI--DAPTAWAVVGEDPAA--------------------------------------------
---------VP-DLVVMTAAADGAT----ADLADAAHRRTRQVLAWAQTWLTSPAFSKLILLTRGAVAADDTTEPDLTTAAVWGLIRSAQTENPG-RFTL
VDTDAGKPA------WRTLR-KVAGSDLPQLALRKRALRIPRLTRLAAPA--RSAPLLTDPHGTVLLTGGTGLLGAALARHLVTHGVRDLLLTGRRGPDA
PGA--AGIEAE----LTALGARVTIAACDVADREALAGLLATLPA-D-RPLKAVVHTAVVMDDGIVLSLTPERLDAVLRPKVDGALALHEATKDLDLSAF
LVFSSIAGILGGAGQGNYAAANVFLDALARHRR-AHGLPAASIAWGLWAGRDLTTS-----GTSRLPVHPLPLAEGLELFDAVCGLDQGNPVARLDTAEL
RRQAASG----------------------NLPPTL-------RALV-HK---P-----SRPAAANAPAEASELKHRLAAM----TDAERDETLLDLVRRL
MATVLGHDAIGAQQDFKDLGFDSLTALTVRNELNAATKLTLPPAVVFDFTDPSALAQHLKRELLEC------
>tr|A0A0N0SKD1|A0A0N0SKD1_9ACTN DNA-binding protein OS=Streptomyces sp. MMG1533 GN=ADK57_29555 PE=4 SV=1
------------------AEVVRRALLRPEWTAVEPPGGV-VDTGCWELAGPDRAP--------------------------------------------
---------EP-DTVVVMAGAPMTD----ADPLPAVHLLTGRVLRALQDWQDDPRTSRLVVVTREAT----APEPDLAGAAVWGLVRAAQAELPG-RVVL
VDVDGRPES------LRLLP-SAVATGEPQLSVRQGRLAAPRLAGHSELS---TGGGAFGPDGTVLITGGTGALGAELARHLVAYGVRHLLLTGRQGPQA
PNA--DELRGT----LEELGAEVRIVACDAGDRDALAEVIKGCAP----APTAVVHAAGVLDDGVLAALTPERMATVLRPKADAAWHLHELTRDLDLSAF
VLFSSVSGLLGRAGQGNYAAANSFLDALARHRS-RLGLPAVSLAWGPWEHGGGMAGAD--SRRSGEVLRALSVEQGLALFDAALRADEPVLAPLLDRAGL
--RSAPG----------------------PVPPLL-------RGLV-PP-GRPAAATTDSPPGTEQPWEPGAWRKVLAEL----PSAQREDALAELMSAD
VAAVLGYDALPAGKSFAELGFDSLMAVQVRNRLSMALRLRLSAAVVFEHPTAQGLARHALGLLDDLPE----
>tr|A0A069JZR7|A0A069JZR7_9ACTN Uncharacterized protein OS=Streptomyces sp. NTK 937 GN=DT87_20560 PE=4 SV=1
------------------GRAHGDLLFRLDWVRLLDPPAP-AEPPRYGFLGEPGAD--------------------------------------------
---------AP-AVVVACPT-TAGG----TDRASAARCAAAWALRLVQDWLAEERLSRLAVVTSGAVATTGTGDAVLAHAPVWGLLRSAQTENPG-RFTL
IDVDEHPAS------AEALV-RALASAEPQTVVRHGVAYAPGLVRASRPQSA-DASRRLRPDGTVLVTGGSGSLGTAFARHLVAHGVRHLLLVGRRGADA
PGS--VELCAE----LAELGADVTVAACDVADRTALAALLAAVPP-A-HPLTGVVHTAGVLDDGVIPALTPERLDRVLRPKADAALALHELTRDSDLAVF
ALFSSVAGVFGSGGQGNYAAANAFLDALAQHRR-ALGLPGTSIAWGPWQQSGGMTATLDLRRMARSGFVPLRTEEGLALFDAAVEGQDAVLVARLDPAAA
---GTPG----------------------AP--LS---------RV-PG-RGPV--RRASTALTRSGAGGGSLGRRLAAA----PAPARGALLLSEVLAE
AGLALGHPVIDADRALAELGLDSLAAVELRNRLAAVTGLALPATLLFDYPTPRAVAAHLEERWSQAAP----
>tr|A0A0C2BAZ7|A0A0C2BAZ7_9ACTN Uncharacterized protein OS=Streptomyces sp. 150FB GN=QR77_00870 PE=4 SV=1
------------------ARAHGDCLFRLDWTRLPDPLSP-GGQPVWGVLGEVDAA--------------------------------------------
---------AP-AVVVATGVSATDG----SDIASAAHRTATWALKLVQDWLKEESLSRLVIVTSGAIVTTDADTAALAYAPVWGLVRSAQTENPG-RFAL
IDMDEHPAS------RQVLT-HVVASGEPQTAVRKGVAYVPALVRAPAPV---DTRRRLNPEGTVLITGGSGSLGVLFARHLVVHGVRHLLLAGRRGAAA
PGT--AELCLE----LAELGAQVTVAACDVADRTALVALLAGVPE-A-HPLTGVVHTAGVLDDGVIPALTPERLDRVLRPKADAALALHELTRDLDLAVF
ALFSSVAGVFGSGGQGNYAAANSVLDALARHRR-DLGLSGTSMAWGPWQQSGGMTADLDLRRMARAGFVPLTAEEGLALFDTAIGGPDAVLVARLDHAAF
GAAAAPG----------------------AP--LS---------RV-PG-RESV--RRIAAAAD-EPDGDDSPRRRLAAA----PAEARVGLLLAEVRTE
AAASLGHAAIEPDRPLAELGLDSLAAVELRNRLATVTGLSLPTTLLFDYPTPRAVAEHLEELWSREAP----
>tr|A0A0F2TC25|A0A0F2TC25_9ACTN Uncharacterized protein OS=Streptomyces rubellomurinus GN=VM95_28095 PE=4 SV=1
------------------EGTAAEAVFELAWQPAEAVAEQ--GAGWWLLFADRQRT--------------------------------------------
---------GPCAVLHTWSAEPFEP----EGLLEPVDRICAPVLHLVQAGPSGPGLPRLLLATRGAQRVGERALPAVAQAALWGLARVIVLEHGELRPAV
VDLDPDRPAE---SAAALLGEALRPAGEAQLVLRGERRLAPRLERHSAPRPVPPQDGPVRAAASYLITGGLGALGLETARYLVDQGARHLVLVGRQKPSA
QAE--S---AE----LRERQATVLVRSADVSRPEDVTRVLADLDA-ALPPLAGIVHAAGFLDDALLLGLDRDRLRSVAEPKASGAWQLHRATAGRELDFF
VMFSSAAALLGSPSQGNYAAANAYLDALAQYRQ-ARGLPALSIDWGPWARIGLAAGPE---ALAAQGVLALEPRQGIEALDHLLRAGSAQACVPLDHGRL
REAADAG----------------------LLPALL-------TGLL-AA----------EPAAAVPGGPPPELRGRLAVE----PGRRRRAILAEHCRAV
VAKVLKT-RIDPTEPLAAMGLDSLMSLELRKRLEGSLHTDLPATIGWRFPTVDALVPFLAERMGIALH----
>tr|A0A0D8BFG9|A0A0D8BFG9_9ACTN Polyketide synthase family protein OS=Frankia sp. CpI1-S GN=FF36_02635 PE=4 SV=1
------------------D-PVGDALFEVGWRELPENTDLADVAGWWLLFTDETRP--------------------------------------------
---------VPCGVLYAWSAPPAEG----GDTRGGEEPRAISLLHLVQA--DRPGAPRLVVVTRGAQRVREEAAAALGQAQVWGLSRVIALEHGELRPLI
VDLDPASAAD---ASTALLAELSRQDGIGQLALRAGRRYAPELRPASPPAETPPGRRAIRSDATYLITGGLGALGLETAKYLVAQGARQLMLLGRSVPSA
AAQ--R---ED----LAARGATVETRAVDVADPGDLAAVLKEIDA-SMPPPAGVVHAAGVLDDGLLIHLDRERFRTVTAAKAAGAWHLHRLTADRDLDFF
VLFSSAAALLGSPGQGNYAAANAFLDSLAQYRH-ARGLPALSIDWGPWSDIGLAARPD---ALAGQGLLSISPRDGIDALDRLLGVPVPQVCVPLDRGRL
RAAAEDG----------------------SLPGLL-------AGVI-GA----------SAGTAGGPQRSGEIRRRLAAP----PGRFRRAVLVAHCTEV
AAQVLRL-RVDVTAPLAAMGFDSLMSLELRRRLETSLQIELPATVAWRFPTIDALVPFLADRLEIDLA----
>tr|K4QW58|K4QW58_9ACTN Uncharacterized protein OS=Streptomyces davawensis JCM 4913 GN=BN159_0686 PE=4 SV=1
------------------RDPASRDLYGVAWDEAEAV---EGRAGRWLLFADRGGD--------------------------------------------
---------GLDGIVDARALDLTED----ATLLAAHDAACVPALRLVQQ-LD----PRLVLLTRGAQQAEG-DRTAVAQAALWGLARVAKLEHGELRPVI
VDLDPARPQG---EAERIVDELLRPGDDDQVALRAGTRRTPALRPWTGG-SVGPESAPVRPDASYLITGGLGALGLETARYLVAQGARHLVLVGRSAPST
EAE--R---TE----LRGSA-EVSTLRADLSRHDDVADVLARIDA-DMPPLAGVVHAAGVLDDGLLTGLDPDRFRAVAAPKSVAAWHLHRATAGRDLDFF
VLYSSAAAVLGSPGQGNYAAASAFVDALAHHRR-SLGLPALSIDWGPWAEIGLAARPD---ALSARGVRSISPEQGIATLDLLLRGSATQLCVPVDRDGL
SGHTGGG----------------------LLGTLA-------DDSG-RA----------E---AG-PRGQDDVRRRLAVE----PGRRRRAVLIDHCRAL
AARVVGA-TVDTSAPFTAMGFDSLLALELRMGLETSLGVSLPTTVTWRFPAIDKLVPFLAERMEIELE----
>tr|A0A069JPK9|A0A069JPK9_9ACTN Uncharacterized protein OS=Streptomyces sp. NTK 937 GN=DT87_01575 PE=4 SV=1
------------------ADPFDEALLDIAWRPAPLPA--GQRPGTWLLFTDAGGT--------------------------------------------
---------VPDGIVQAWTVTLTSD----GPFPAARDAACLPALHLVQEGTD----PRLVLLTRGAQRVDA-DRPDVGQAPLWGLARVIGLEHTELRATV
VDLDPARPDG---ESGQLLAEVLRDGADDQVALRGEARLTPVLQPWTAPARPAPGAPPVRPFGTYLVTGGLGALGLETARYLVDQGARHLALVGRGAPGA
DAE--R---TG----LRTRA-EVTVLAADVSERAAVDGLLARVDG-SMPPLAGIVHAAGILDDGLLTGLDADRFRSVAAPKSAAAWHLHRATLDRDLDFF
VLYSSAAGVLGSASQGNYAAASAFLDGLAHHRR-SRGLPALSVDWGPWSRIGLAARPD---ALSTRGIRSISPEQGIAVLDRLLTGTATQVCVPVDRARL
REHPGGG----------------------LLRTLL-------DEPG-QE----------H---DGGAGPADDVHRRLAVE----PGRRRRAVLTEHCRAV
AAGLLGG-GIDAGAPLTSMGFDSLLSLELRKSLESSLRVPLPSTVTWRFPTIDALVPYLADRMKIALE----
>tr|A0A0F7NE33|A0A0F7NE33_9ACTN Uncharacterized protein OS=Streptomyces sp. CNQ-509 GN=AA958_29290 PE=4 SV=1
------------------ADPLAEALYDIDWRQTPGKAE-GAEPGTWLVFADAGGI--------------------------------------------
---------RPGGIVHAWAAALAED----DTLLAVQDAATVPALHLVQEGQE----PRLVLLTRGAQRAAG-DELSVGQAPLWGLARVIGAEHAELRPTV
VDLDPARPDG---EADLLLAEVLRPGDDGQVALRHGERLTPALQRWTPS-ETAPGAAPVRPDGTYLITGGLGALGLETARYLAGAGARHLVLAGRNAPSA
AAE--R---AE----LRDRA-EVAVVSADVSQRGSLDEVLARIDA-TMPPLAGVVHAAGVLDDGLLTGLDRERFRSVAAPKATAAWHLHHATSDRELDFF
VLYSSAAAVLGSASQGNYAAASALLDTLAHHRR-ARGLPALSIDWGPWSDIGLAARPD---VLAARGIESISPGDGIATLDRLLRTDAAQVCVPLDRDKL
RDHPGGG----------------------LLGTLL-------GDAP-GE----------S---PASRPATSEVRRRLSVE----PGRRRRAVLTEHCRAV
AARVVGA-RIDTSAPMNSMGFDSLLSLELRNSLVSSLRVELPSTIAWRFPTIDALVPYLAERMDVELE----
>tr|A0A0F4K569|A0A0F4K569_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. NRRL B-1568 GN=VR41_13920 PE=4 SV=1
-----------------VQSTVDSWRYREVWNPLGSTSS-AAPSGTWLVLAPTAGVDDAWIAATALGQAVRIDVDAS--------------SDRTQLAGL
LAEATADGAQFDGVLSLLALDDAPQ-------AAGTSAGLLGTVVLLQALSDAGITAPVWAVTRGAVCAVSEPPASPEQAAVWGLGRVAGLERPERWGGL
VDLPEMLDE---Q-AVRRFAVLAGIGEEDQVAVRASGILGRRLVPAPAEE----NTGRWEPAGTVMVTGGTGALGAHVARWLARHGAPHLLLLSRRGPQA
PG------AAELEAELSALGTRVTITACDVADRDALAAVLAAVPAEH--PLTGVVHAAGVLDDGVLDGLSAERFETVLRAKVASARLLDELTRDLDLSVF
ALFSSVVGSVGNSGQANYAAANAALDALAARRR-ALGLPATSIAWGPWTGDGMADRAR--AAGARISTAVLDPESAMSALAQAVNEPAPTTLLGLRPSRL
LAEIPE------------------------ARRILDRLVE---A---------------RRESASA---TQQLRKQLRE----GTEAERLALLLGMVRAR
AAAVLGHHAIGGDKAFRDYGFDSLTAVELRNQLAGATGLSLPTSLVFDYPTPRALAAHLVAEL---------
>tr|X8B2N2|X8B2N2_MYCAV Short chain dehydrogenase family protein OS=Mycobacterium avium subsp. avium 2285 (R) GN=I549_4773 PE=4 SV=1
-----------------KSRSIAEDRYEIRWEKSTV-PG-PEAEATWLVVGDDDAVAPLV-AL-ARGHHRILVLPSD--------------ADEERLEIV
LRAAAAEEAPLRILVAALDSGTAPS-------MRMQHRVLAGTRRLFRAAAAAELRQPIWLVTRGAQRVTDADTVFPDQSCLWGFGRAASLEYPQLWGGL
ADLAQGSAE---E-WSRLASPRDPAVGEDQIALRGSDIYVPRLTRRSGQA----AALTLRADATYLVTGGLGSIGLEIAGHLAAQGARHLVLTGRRAPGE
AA------QRRIDALSQQHGCEVRVIAADVADAHHVARLLGAVRAELP-PVAGIVHAAGEIGTTPLSDLEDAEIDRVFAGKVWGAWHLSEAAADLRLDFF
VSTSSIASVWGGLGQTAYGAANAFLDGLAWRLR-EQGVNGISVNFGPWAAGMADENAR--ARLAQRGIKTLSPADALAGLADVMATA---VVARIDWTRF
LPQQAG------------------------QRSLLAELAR---E---------------I-PDPSG---KTGLVERLAG----APVQQRRKLMTEFLRNA
VAEVT-RAEIREDAGFFDLGMDSLMAIELRRHIEQGVGKQIPATLAMDYPRLSDVAEYLLGDV---------
>tr|U5DKA0|U5DKA0_9CHRO Polyketide synthase module OS=Rubidibacter lacunae KORDI 51-2 GN=KR51_00012640 PE=4 SV=1
------------------------------------------PIGDWVIFADTDGIARNLAERLADGETCTLVYRDTPPDPTDISTLQLDPQDPGSTDRL
LDRLQERGAGLQGIVHCWGLDAPVAEMDAPALAAASRLGCGTVLTLVQALIRGLSAPRLWLVTRAAQPAGESLLSGVSQASLWGMGKAIALEHPELRCSR
IDLDANLAIS--AQAGQLWAEVRSGDPEDQVALRQDHRFVARLVRNQNEKPPPPAELSLSSEGTYLITGGLGGLGLLVAEWLVKHQVRHLALVSRRGSDA
---TVQAKLAL----LEERGAKVDVIQADVTDEDAMAAALERIRRSP-WPLKGIIHSAGALDDGTLQQQTWEKFATVLGPKVQGAWILHRLTQPDPLDFF
VSFSSAASLLGSAGQANHSAANAFLDGLAHYRQ-SVGLPGQSFQLGIVGQVGEAAERGADRRGERQGMGSINPQQVLVALEGVLRQEIPQVLAAIDWTTA
ARL---------------SPQWRA-------WPYLAD--------F-AASGA--------EMSPEGDTAIASFVQQLQQ----APAPEQRALLATFVRQQ
VAQVLGMAAIDAEAGFFDLGMDSLTAVELRNRLQTGLGISIAATSLMDYPTLAALLEFLADRLL--------
>tr|Q847C6|Q847C6_NODSP NdaC OS=Nodularia spumigena GN=ndaC PE=4 SV=1
------------------------------------------LSGDWLIVTDN-NLPLAIQAHLKDHSSCAIASPENSS---ELETWL------------
-----ANSPSPRGIIYLVSD-------RHHQPESILCDRCSYLLNLLQAIQ--PNPPKLFLVTAGGQPFGLEKPSFLTQSPLWALGRVIALEEPELWGGM
IDLDPNADMA--QNLAALLPALTNSAREDHLLFRNEQAYVARLV--------PPKPVTIQAQATYLITGGIGHLGLELARHLVDLGAKNLILTTRRQFPP
RTSAIIQTLIT----LEAHGASVEICQADVGDFQQMSDIFENIQKTS-SPLRGIFHLAGVSGRARLSECTFDDIEDVFQAKVRGSWNLHQLSLKTELDYL
VFFSSAGAIWGAKEQGLYDAASHFMDALAHLRS-RQGLPATSLNWALLAGNGIVSPEYE-DWLKQIGMKEIALEPAFRAMNAIMA-GKTQVLADVDWVRF
KNI---------------YQFHGN-------KPLLEQ--------L-GELPI--------PVKS--EKASSSSRRFIEE----QPPGERREHLFAYIGKQ
VATILGIKMPDPDQGFLAMGIDSLLSIELKNRLEKGLEVSLPASLIFDFPNITRLVDYLVEQVF--------
>tr|A0A0D6YGA9|A0A0D6YGA9_MASLA Beta-ketoacyl synthase OS=Mastigocladus laminosus UU774 GN=SP67_20895 PE=4 SV=1
------------------------------------------ISGNWLICTD-RNLALAIQEELKHYGYCAIANP-NSS---ELETWV------------
-----ATSPSPRGIIYLLNAD------HSNQYESTLFNRCSYFLNLLQAIK--PSPPKLFLVTQGGQPFGLERPSFMTQSPLWAMGRVIALEEPELWGGM
IDLDPHADIA--QNTTFLFSGLINSVTEDHLLFRNSQTYVARLV--------ATKPVIIQSQATYLITGGIGHLGLQLAHHLVDLGAKHLILTTRRQFPS
KAAEIIQNLKI----LEQKGVSVEVYQADVGNFEQMSRIFTNIQKTS-YPLRGIFHLAGISGRARLSDCTLDDLKEIFQAKVRGSWNLHQLSLETQLDYF
VLFSSAGAIWGAKEQGLYDTVNHQMDALAYLRH-LQGLPATTLNWALLAGNGIVSQDYE-DWLKQIGMNEIPLDKAFQAMDTIMA-DKTQILADVDWIQF
KNI---------------YQFQGN-------KPLIEK--------L-GKSPT--------PIKP--VKKSKSQRSFLEN----VPPTERREHLLEYIGKE
VAKILGIKIPNPEQGFIEMGIDSLLSIEFKNRLEKGLEIALPSTLIFDFPNIRKLNNYLFEQIY--------
>tr|U5TVV1|U5TVV1_9NOSO McyG OS=Nostoc sp. 152 GN=mcyG PE=4 SV=1
------------------------------------------IAGDWLIVTDS-NLALAIQEELKHHSSCAIANPEHSL---ELDT--------------
---------SLHGIIYLVGD-------RNEPSESILFNRCRYFLNLLQAIK--PNPPKLFLVTQGGQPFKVNQPSFVNQSPLWALGRVAALEEPALWGGM
IDLDPHADIA--QNIAALLPALTNSAKEDHILFRNHQAYVARLV--------PTKPVTIQAQATYLITGGIGHLGLQLAHHLVDLGAKNLILTTRRKFPP
RTSEIIQNIIN----LEKKGASVEICQADVGDFPQMSDIFERIQKTS-YPLRGVFHLAGVSGRARLSECTAADIAEVFQAKVRGSWNLHQLSLGIELDYF
VFFSSAGAIWGAKEQGLYDAASHSMDDLAYLRR-LQGLPATTLNWALLAGNGIVSPEYE-DWLKQIGMEEIALNKAFGAMDAVIT-GEIQVLADVDWVRF
KNI---------------YQFNGK-------KPLLEK--------L-GKAQV--------SVK-----ESSSSRRFIEE----VPPGERREHLFEYVGKQ
VSTILGIKISEPDQGFLEMGIDSLLSIELKNRLEKGLEVSLPASLIFDFPNITRLVDYLVEQVF--------
>tr|Q7WRJ0|Q7WRJ0_9NOST Peptide synthetase polyketide synthase fusion protein OS=Anabaena sp. 90 GN=mcyG PE=4 SV=1
------------------------------------------ISGNWLIFTDSENLALAIQQQLKDCGSCAIANLENSS---ELETRL------------
-----ASSLCWRGIIYLVNGG------EGDQYESTLFNRCHHLLNLLQAIK--PHPPKLFLVTQGGQPFRLEQPSFVTQSPLWALGRVMGLEEPELWGGM
IDLCPHADIA--QNLVALLSGLTNSVTEDHLMFRKGQAYVARLS--------PTKPVTIQAQATYLITGGIGHLGLQLARHLVDLGAKHLILTTRRQFPL
RAGEIIQNIKT----LEQKGATVEVCQADVGDFEQMSRIFTKIQKIS-DPLRGIFHLAGVSGRAKLSECTLDDIAEVFQAKVRGSWNLHQLSLATQLDYF
VLFSTAGAIWGAKEQGLYDTASHFMDALAHLRH-LQKLPATSLNWALLAGNGIVSQDYE-DWLKQIGMKEIALDKAFAAMTAVME-GKTQILADVDWVRF
KNI---------------YQSKGN-------KPIFEK--------L-GEYQN--------SVKG--IQQSISTRRFLEE----IPPGERRQHLFEYIGKQ
VGTILGNKIPDTEQGFLEMGIDSLLSIELKNRLEKGLEVALPASLIFDFPNIRRLVDYLVEQVF--------
>tr|A0A0M8VZC5|A0A0M8VZC5_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. NRRL WC-3618 GN=ADL01_17420 PE=4 SV=1
------------------RSTLDGWRYRVTWKPLANGARAGALSGTWLVVVPEEAAAHVSEALTQAGASVVQLGFAEA----EL--------DRKGLVEH
AQ-SAVGAAEPAGVVSLLALAEHPHP-----AHPVLPTGLAATVALVQALDDAEIGARLWAVSMGAVSTGRSDLVSAAQAQLWGLGRVVALEHPERWGGL
IDLPQTPDSRTATRLATALAGITGTGFEDQVAVRGSGLFVRRLTHAPLVTH---PSRTWTPRGTALITGGTGALGAHVARWLVREGVEHLVLTSRRGLDA
PGA------GELKAELEELGAEVTITACNIADRDAVAGLLDELAAG-GHTLRSVFHAAGVSPALPLADTAPADLADALDAKAAGAAHLDALLGDTELDAF
VLFSSIAAVWGSGGQSGYAAANAFLDAIAERRR-ARGQAATSVAWGAWGGSGMAATAEAEEHLRRRGVALLGPDLAIGALAQALTYDETCLVADVDWERF
APT------------------FTAARP----SAFLGGLPEL-RPQR----RQ---STS---APAGGGEPVSEWASRLTGL----PEGERQRLVLDLVRTE
AAAALGYDAVEPTRAFRELGFDSLTAVELRNRLTAATEVSLSATVVFDHPSPEVLARHLLAEL---------
>tr|A0A0F2T3T2|A0A0F2T3T2_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces rubellomurinus GN=VM95_37040 PE=4 SV=1
------------------RSAVDDWRYRIAWKPLADRPA-AALTGTWLVVVPAGRTEDAVRALDGHGARTVLLETTGA----DA--------DRAVLAER
LR-PLVDGTDLAGVLSFLALDDKRLD-----GHRSLTACVGLTLVLVQAMGDLGLRIPLWCATHRAVATGPSDPADQVQAQLWGLGRVVALEQPHLWGGL
VDLPAEPDARALGRLAGVL---AGAGDEDQVAVRPAGLFARRMVHAPLGG-----VRDWRPGGTVIVTGGTGSLGPRLARWLAERGAEHLVLASRSGPDA
PGA------ADLAAELTATGVEVTLAACDVADRDAVAALLDGLRAE-GRTVRAVVHTAAFIELLPVDGTPLESLDQVLAAKVDGTRHLAELLDPEALDAF
VLFSSIAGFWGSGDHAAYAAANAALDALAEAGR-ARGLPMTSVAWGVWEDAGDQDVERTRRKVQAQGLPLMRAELAVAALQQSLDHDDTFVIADIDWARF
VPL------------------FTALRP----SPLLTDLPEA-RAVL----AA---PEA---GGAPGAGNDSELRRVLVEL----SEADQLRTLTELVSAH
AAAVLGREAIKPERAFKELGFESLTAVELRNRLNAATGLRLPATLVFDYPTPAALAAELRREV---------
>tr|A0A014KX15|A0A014KX15_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. PRh5 GN=Z951_46615 PE=4 SV=1
------------------RSTIDSWRYRATWQQLPDPA-APALTGTWLVVVPAGQEEHTLQALRAHGATALPYAVDAH----HI--------DRATFRER
LD-QVTEESQPTGVISLLALDTEPLA-----GHSAVSAGLGATTALLQALDDAGISAPLWCVTQGAVATGRSDLPHPEQSPIWGFGRVAALEHPQRWGGL
IDLPAAMTHHTAGRLAALL---APGQPEDQVAIRTTGTYARRLTRVPAANT---APAPWEPSGTTLITGGTGGLGAQVARWLADRGAPRLHLVSRSGPDA
PGA------SELSEELTALGTDVTITACDVSDRAALRRLIDSVPA--EHPLTVVIHTAGTMELGQIGELDPGRLQPVLRSKALAAAHLHDLTQDLDLTAF
VLFSSNAATWGSGQQAAYAAANTYLDALAEHRR-ARGLPATSLAWGPWGEAGMAADQHTLSHLERRGLSPLPTDLAIASLQHALTHDDTAVIADVDWERF
GRT------------------FTAQRP----SPFLTRLMPS-SAEP----AT---STA-------IAADDNPLRQQLSAA----PAAQRHQLLVRHVQTL
AATILGHDAVPPGQPFQELGFDSLTAVELRNQLASTTGLALAPALVFDHPTPNALATYLGAEL---------
>tr|K1V3E7|K1V3E7_9ACTN Polyketide synthase family protein (Fragment) OS=Streptomyces sp. SM8 GN=SM8_03688 PE=4 SV=1
------------------RTLLDGWRYRVTWQPVPLGND-DGTGRPWLVLTPAGHDDALAATF---GEHAVRLAVPAD----ED--------GTAAL---
LD-GAADGTAYAGVLSLL------T------D------GTARPDTLLRLLA---IDAPLWCVTRDAVSVGRSDAADPDRAALWGLGRVLALDEPERWGGL
VDVDHVADARTVDRLRAVLTAATDGPAEDQVALRASGAFGRRLSRAAAPA----PDITWHPAGTVLVTGRAEGFGGHVARWLAAHGATGVLLAGPAGPED
VAT------TALRAEVEALGATLTVVRHSPADAAPLTEALA-AQTD-DRPLTAVFHTGDTGEETP------G-----VTGARAAYEALTTAVGDRDLDAF
VVFGSISAVWGVGGQGAGAAAGVCLDALVQRHR-AHGTNAVSVSWGAWQGA---GPDGLAAHLRANGLPAMEPARALDALAPAIGEAPASVVADVAWDRF
APA------------------FTRTRA----GLLLTGVPEA-REAL----ST---TGG---DA--DAGTASALRERLRQS----DPSERPRTLLDTVLTE
IASVLGHAAVPAENAFNDLGFDSLTAVDLRNRLTTATGLTLPATLVFDYPTPAALAAHLLTEL---------
>tr|Q1PCG2|Q1PCG2_9ACTN Polyketide synthase I protein (Fragment) OS=Streptomyces sp. 98-62 PE=4 SV=1
------------------PVLVDGYDYGPAFQGLRAVWGDAALHADGLRTAPPGTDGP--VSLYASGATALRVRIRGG----DT--------LSLDLAAA
VEALVSRPVDPAALTSPVVLDERGTA-----AADAVPDATGRVLAVRDWLADERRGARLVVLTGGAVATGTED-TDLAGAAVWGLVRAAQGEHPDRFVLV
DSVAHDGGGESAS-GPGVFAT-AAASGEPQLALREGTVRVPRLARAAVTGA---FGPAPDPHGTVLITGGTGVLGAVVARHLATHGVRRLVLAGRSGTAF
DDF----------GDLAERGTEVVVARCDAAERDQLAALLADMPA--ERPLTAVIHLAGVLDDGLVTDQTPGRLDAVLRPKADAAWNLHELTRDLDLSAF
VLFSSAAGTIDGAGQSGYAAANAFLDGLAAHRA-AQGLPALSLAWGFWEQR---LTDADVERMARAGVRPLPTEEGLRLLDAALAADVPLLPVGLDPRAL
PPVL----------------ARSGARA----RPSYGGLPRH-R---------------------------RSAAERLAAL----GAAEREAALTELVRTH
VAAVLGHMVLDPRRSFREAGFDSLTAVELRNRLGNAVGLRLPATLVFDHPDAEALVRYLKTEL---------
>tr|U5QR00|U5QR00_9ACTN EbeG OS=Streptomyces aburaviensis GN=ebeG PE=4 SV=1
------------------RSVLDGWRYVIDWQPLREPSG-PALTGTWLLATPAGHTGDAERALAEHGARVLRIELDPA----GD--------RAGLAARL
RE-LAAGHEPFAGVLALLAPAGQPHP-----EHPALSVGLVLTLALVQALGDAGVGAPLWCATHGAVSVGGADLVSPGQAALWGLGRTVALEHPDRWGGL
VDLPGRPDARAGARLCGVL---AGIADEDQVAVRSGGLYARRLVRAAAPDD---APAHWRPRGTVLLTGATGAVGPYLARWLARGGAEHLVLTSRTGATG
PAT------AALRSELAATGTRLTIAACDVADRSALAALVAGLAAD-GTPVRAVVHAAAFIRLSSLDATTTAEFAEVVAAKADGARHLDEIFDRDELDAF
VLFSSVAGVWGSGDHGAYAAANAYLDALAQQRR-ARGLRATSVAWGLWNTPGPSK--AVESRLFRQGLPLMDPEPAVAALQQVLDRDETFVLVDVAWDRF
SPT------------------FASARP----RPLLDAIPEA-RRGR----PA---ERQ---EEQA-ADVLSRWRRRLAAL----PAAEADRELLELVAGT
VAVVLGHESIATGRPFRELGFESLASVDLRNRLNAATGLRLPTTVVFDHPTILALAGRLRTEI---------
>tr|A0A0M9Z2R2|A0A0M9Z2R2_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. XY431 GN=ADK60_17650 PE=4 SV=1
------------------ESVIDSWRYRIGWQPLPDPPAATAAAGTWLVVLPAGHDDDPLLALAEAGATVVTAELTDG----AV--------RRTDLADT
LA-TALGDRVPTGVLSLLAAADRSHP-----DHPALPTGTALTVALVQALGDLALTAPLWCVTAGAVSTGPDDVTHPRQALVWGTGLVAALEQSARWGGL
VDLPPDLDARTRTRLAALLTASDGVGREDQLALRPAGLLARRLRRAPRNDA---RPEHWKPRGTVLLTGGTGAVGPHLARWLARSGATHLVLPGRRGPQA
PGA------AALAAELAVLGVRLTLPVCDLADRRAVAALLTGLEAA-GDRVTAVVHAAAFVALAPLDGTPMSAFEQIVAAKAAGAEHLDALLDR-ELDAF
VLFSSIAGVWGSGDHGAYAAANAYLDALAQHRR-ARGLTATTVDWGIWQAEGED---ADLFKLEQHGLPRIAPDLAVQALRQALDDDETVLVADVDWERF
AAV------------------FTSTRP----SPLLTGIPEA-RRAL----AA---ATG---DEAP-AA--ALLRQRLTAL----GESEQHRLLLDLVRTH
AAAVLGHDAIRPGAAFQDLGFASLTAVELRNRLNTATGLRLPSTLVFDHPSSVALAREIRAEL---------
>tr|A0A0F5A6K6|A0A0F5A6K6_9ACTN Beta-ketoacyl synthase (Fragment) OS=Streptomyces sp. MUSC164 GN=VT50_27135 PE=4 SV=1
-----------------DRSTVDNWRYRINWKPVIDQPSEAPITGTWMVVVPPVDLAGRIADVERHGARMVRVDLDGTE-----------PE-RSSLADL
LRAAQEDTPAIDGVLSLLALDEEALA-----EHPGIPRGFAGTVALVQALSDIDIDVPLWLATTGAVSVGRDRVGRVKQSLVWGLGRVVGLEYAQRWGGL
VDLPESPDALDERALDRLVGLIGRSGDEDQVAVRASGVFARRLVRAPLGDAR--PARVWEPRGSVLITGGTGALGGRLARWLAHAGAEHLVLTSRRGLEA
PG------AAELRDELTALGTRVTVAACDAADRGALRELLDGLPAEY--PLTAVVHAAGVLDDGLIDTLTVPRAQGVFRPKVDAVVNLHELTRDLDLSAF
ILFSSYAGTVGGAGQGSYAAANAFLDALAQQRR-AQGLAATSVAWGAWGGGGLVDDAT-AAQLKRRGMPPLVPELAVDALQQALDHDEVDIVADVDWERY
APGFAS------------------AR----PRPLLNELPEV-RQAL----E--------AAEAELG-AALTGLAVRLEGL----SAVEREAEVLDLVRSH
AAEVIGYEAVEPERAFRDIGFDSLTAVELRNGLSAAAGVNLPVTMAFDYPTPTVLARFILGEV---------
>tr|H8GEN3|H8GEN3_9PSEU Polyketide synthase family protein OS=Saccharomonospora azurea NA-128 GN=SacazDRAFT_02066 PE=4 SV=1
-----------------RQADIDDKRYGVTWQTLDPA--PAKLTGTWVVVSVVSSWVQGALALARAGATVRHLRLDEAD-----------TD-RAVLAGK
LREL---GAEPSGVLSLLAFDERGHS-----EHPAAPVGLALTVALVQALGDVDVRALLWCASDGAVSVAPEAPRNPGQAQVWGFGRVVGLEHPERWGGL
VDLPAT---VEERYQAGLANAVGNAAEEDQLAVRGRIPLVRRLVRTPLRDAA--PVRSWRPEGTVLVTGGTGALGSHVARWVAREGAEHVLITSRRGMDA
PG------AAELRDELTQLGSRVTIAA---------------LLAEH--PVTAVFHVAAVLDDSLIDSLTVEQIHRVAGVKVGGTLNLHELTADMPLSAF
VVFSSFAGTTGGPGQGNYAPGNAFLDAFAQQRR-AHGLPATSLAWGPWAGGGMAEGDG-GELSRRHGLKDVSPELSLEIMKQALDHDETFVVAEIDWERF
FLAFTS------------------SR----ARPFLYGVDDV-QRML----A--------SGASSAK-AAPTELGSRLAQL----SEAEQERELVKIVRDQ
VATVLGHDRIDVKAAFKDLGFDSVTAVELRNRLNSVTGLKLPATLIFDFPSAASLVAHLRTEL---------
>tr|A0A0N1H7I1|A0A0N1H7I1_9ACTN 6-deoxyerythronolide-B synthase, 3-oxoacyl-(Acyl-carrier-protein) reductase (Fragment) OS=Actinobacteria bacterium OV450 GN=OV4
-----------------TIHSRDENAVEPVWTRHAEGTLPTTVDGAYELLLERGYLPEQAHDAHAGGAPALRVCIADAE-----------GQ-PVLTVGS
LVSRQLGGARPESLFEIAPLPASAVASADQHVWGALPEGAAQTLAVVQEWADERAETTLVVATRDAVVVDA-EGIDLAQAPVWGLVRAAQAENPGRIQ-L
TDLTASTDD--------LAAVIAS--GEPESAVRPDGLRIPRLTAVPAPVSQ--GPIALDPAGTVLITGGTGGIGAHLARHLVVHGARHLVLTSRRGPEA
EG------AGELAAELGELGAEVTITA-------NITTLLASIPAEH--PLTGVVHAAGTGDNGLVATMDAGRLDRVLAPKADAAWHLHEQTRHLDLPLF
ALISSAGGLTLAAGQANYAAANTFLDALATHRH-AQGLAAQSLAYGLWASTGMGTDTD-VKRMERQGLPPLQPEEALALFDAAYASGRPATPLHVNRTA-
-LAART------------------DE----LPALLR-------SAT----P--------APQSASG-AGANDLAARLAGK----TEEERDSALLDLARAH
VAAVLGHDAIAPDRAFQELGFDSLSAVDLRNQLKAATGLRLPATLVFDYPNARAVAKYIGESL---------
>tr|A0A0A0NDR0|A0A0A0NDR0_9ACTN Uncharacterized protein OS=Streptomyces rapamycinicus NRRL 5491 GN=M271_04690 PE=4 SV=1
-----------------EQNTVDGWRYKAVWKPLASA--ETTLSGTWLVAVPEACLVAAVLGLAGRGAHVVRVVVGAAD------------G-REAITER
LRAAAVEPSGVAGVLSLLGLDESAHE-----SFEVVPAGLAATVGLVQGLGDAGVVAPLWCGTRGAVSVGRDRLVSPVQTMVWGLGRIVGAEYPQRWGGV
VDLPET---MDSRAMARVAGVLAGAETEDQVAVRGSGVFAKRLVRASAPEAT--DADGWRASGSVLVTGGTGALGGHVARWLARTGAEHLVLTSRRGMEA
EG------AAELKAELEGLGARVTVAACDAADRDALAAVLNGIPREF--PLTAVVHTAGVLDDGVLDALTVSRTAGVLRPKVGAVRNLHELTAGMDLSAF
VLFSSAAGTIGGPGQGSYAAGNAYLDALASQRR-ADGLPATSVAWGAWAGGGLVTGEV-GEQMTRSGMLAMSPELAISALQQALDLDETFLVADIDWTRF
EADAV-------------------------DTPLFRELRNA-RSVT----T--------EKQSTAG-SARAELHDRLEAM----PREKREAALRDLVRAQ
AADVLAHDAVASDRAFRDLGFDSLTAVELRNRIGAATGLRLPVSLVFDYPTPMVLARFLHGEM---------
>tr|M2ZVR2|M2ZVR2_STRMB Beta-ketoacyl synthase (Fragment) OS=Streptomyces mobaraensis NBRC 13819 = DSM 40847 GN=H340_29676 PE=4 SV=1
---------------AGSRGVDRDALFRLDWTRVEVRGDG-GRPRSALVALPGEPLAAELAEVLDGPAVCVTP----EEEPYDAGEFARQSSVSGSSRVV
VAARPGETAGDLPGASLWGLVRSAQTENSDEPELALRDG---LMYVPRLVRDDRLGSATWRLAAGVGAVSVGDRVVAPVPSGWSWTRAAGSLHRLVDARL
LDVAAAGGTA---PADSPDAVLAVRDGAEGPVWDVRREALGSGYAASRPPVL-TLPVAFDPNGTVLITGGTGALGSLVARHLVTRHARNLLLSSRRGAEA
PG--ALELAAEL----AALGAHITFSACDPGDRKAAEALLASVPAE--HPLTAVFHCAGTVSDAVVQNLSAEQVEEVLRVKADAAWNLHELTADADLSAF
VLYSSVAGLLGGAGQAGYTAANAFLDALAAHRQ-AGGAAATSLAWGYWRLTEGMSGLSDADRARHAGVVGLGADEGLALLDAAWDSGLPLLAVRLDLARM
RRQA-----------------RSHSAA----PTLLRN---LVRGGA---D-----------RAAAGPSGPSALLRTLSG----LPAAEREQALLDLVCSH
VAAVLGYDPVNATQGLRELGFDSLTAVELRNRLSAATGLKLPATFVFDHPDPAALARRLGEELAP-------
>tr|E3FL65|E3FL65_STIAD Polyketide synthase AufI OS=Stigmatella aurantiaca (strain DW4/3-1) GN=aufI PE=4 SV=1
---------------VSARPPGEEWLYTLEWKRHEGASLE-HGPE-WLVLSDTTGTGQSLAELMQAGQRCVLVTAADRYAQLGPGRFQVNAAAPEDYRRV
LKDAFGEAGGCRGLIHLWSLDTGGL----EDLEPAQRLGSQSALYLAQAVREGRDTPRLWLVTQGAQAVSQGERVSVAQAPLWGFGRALSLEHPELQTTL
VDVVADAPRA---QAQALWAEMGAADGETQIAWRQGTRSVARLVRGTYGDTG-AVLPSLHANATYLITGGLGGLGLTLAKWMVTRGARHLVLVGR-GEPS
PT--ARTVLREL----EEAGATVVVERADVANRAQMAGVLGRHHEQ--HPLKGLVHAAAVLDDGTMLELDAERFHRPMNAKGHGAWNLHTLTAGWELDFF
VMYSSAASLLGFPGQSNYAAANAFMDALAWHRR-GQGLPGLSINWGAFAEVGMAAASNRGERLRH-GVGSLKPEQGTAVLERLLAGSSAQVAMQLEARQW
LEF------------------Y-PNAS----APLWTV---LLAEQA---------------KTKSRESTSVRFREALSK----AEPSQRGALVEEHLAEQ
IALVLRLEKIDRLRALGELGLDSLMSLELRNRLEAALGMKLSATLLFTYPNLASLAQHVVGRMEF-------
>tr|E3FL63|E3FL63_STIAD Polyketide synthase AufC OS=Stigmatella aurantiaca (strain DW4/3-1) GN=STAUR_3983 PE=4 SV=1
---------------ASSRAIGEEWLYTQDWKRYEGAPLD-HGPEDWLVFADASGTGDALAGLMEAGQRCVKVAASDHYEKLKPGLFRINASAPEDYRRV
LQDAFGEAGDCRGIIHLWSLDSTSN----EHPEHALQLGSQSALYLAQAPRQGRDTPKLWLVTRGAHAVSQDDSLSVSQAPLWGFGRALSLEHPELQTTL
VDVLSSDAPS---QAQSLWAELGASDGETQVAWRSDTRHLARLVRGSYDSLG-GEPISFHPEASYLLTGGLGGLGLSVAKWMVSKGAKHLVLLGR-SEPS
AA--ARLVLDSL----EQSGASVLVERADVSDLDQLSSVLQRHSSP--FPLKGVLHAAVVLEDRTVLELDSERFLKPMGPKVQGSWNLHSLTSQLPLDFF
VMYSSAASLLGSPGQSNYAAANAFMDALAWHRR-RQGLPGLSINWGAFADVGQAAASNRGERLSL-GISSLKPAQGTAVLERLLTGRATQAAMQLDARQW
LEF------------------Y-PSAS----SPLWGQ---LLAERA---------------KAKAEDPGAAQLREALRK----AEPGRRLALLEEQLAKQ
MARVLRLDKLDRMESFTNMGLDSLMSLELRNRLEATLGLKLSATLLFTYPNLAALADHLLGKLSS-------
>tr|E3FL62|E3FL62_STIAD Polyketide synthase AufC OS=Stigmatella aurantiaca (strain DW4/3-1) GN=aufC PE=4 SV=1
---------------VSMRPTGEEWLYTLDWKRYEGAPLD-HGPQGWLVLLDGGKTGTALAGLMEAGQRCVKVAASDHYEKLEPGLFRINASAPEDYRRV
LQDAFGEAGGCRGIIHLWSLDSTSN----EHPEHALQLGSQSALYLAQAVRQGTHTPKLWLVTRGAHAVSQDDSLSVSQAPLWGFGRALSLEHPELQTTL
VDVLSSDAPS---QAQSLWAELGASDGETQVAWRSDSRHLARLVRGSYDSLG-GEPVSFHPEASYLLTGGLGGLGLSVAKWMVSKGAKHLVLLGR-SEPS
AA--ARLVLDSL----EQSGASVLVERADVSDLDQLSSVLQRHSSP--FPLKGVLHAAVVLEDRTVLELDSERFLKPMGPKVQGSWNLHSLTSQLPLDFF
VMYSSGASLLGSPGQTNYAAANAFMDALAWHRR-RQGLPGLSINWGAFSDVGQAAASNRGERLLH-GVGSIKPAQGTAVLERLLTGRAAQAAMHFEARRW
LES------------------Y-PGAS----SPFWAE---LLAEPT---------------PAGAEEPGTLHIRQALID----AEPTQRRGLLEEFLTKQ
VARVLRLDKLDRHEAFTNMGLDSLMSLELRNRLEATLGLKMSATLLFTYPAIASMTEYLLSQPTL-------
>tr|U9VNL7|U9VNL7_9CYAN Polyketide synthase family protein OS=Leptolyngbya sp. Heron Island J GN=N836_21160 PE=4 SV=1
--------------------ALKEHLYEVVWEPAAARAQTLDHPGHWLIFAHSHGIGDTLAQQRQRGHGCTLVLPGTCYQQTQDDHYQLDPAAPEQFQQL
LADLLTK-QPWHGVVHLWSLARDQQPTDGVEPARSQLLNTGSALHLVQALTHTQISPQLWLVTQGAQPIDT-APLQVQQSPLWGLGQAIALEYPELQCMR
LDLDPTEAAA--LSAERLLNELLSAAPDNQIGYRQGNRYGARLKPVTLPSTPMPAIEAVQATGSYLVTGGLGGLGLKAAQWLIDQGAQQIVLASRRGLSS
SA--LADKIEL----LEQQGANITVVQADVAQQDDVGRLLASCP----APLRGIVHSAGVLADGVLQQQSWQQFETVMAPKVSGAWNLHCLTQEMPLDFF
ICFSSAAAITGTLGQGNYIAANAFLDTLAHHRQ-RLGLPALAVNWGAWADVGMAANLSQQQRLAAQGIDLIPVTDGFALLSQLTLQTKPQIAPMTDWSKW
LDSLQT-----------V-------------PQFYEALV----SRQTAARQSSFIS----------------------A-AANPPVFTQKEQLIAHVQQL
VARTLGFTQISLRERLFDWGLDSLMAIELRGHLQQSLACTLGSTLLFDYPTIEKLVDYLAADV---------
>tr|A0A0M8WYI1|A0A0M8WYI1_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. NRRL B-3648 GN=ADL04_26230 PE=4 SV=1
------------------PVPRDDWRYEVAWAPTSGTAA-PVDPARWLVLAATGPWAAAL---RERGFAVA-----D--------TW-----------DV
ADTW-DARPGPDGVLSLLALDEEPHPD-----HPVLPAGLVRTLDLIRTLDPVTPAVPLWCATSGAVSTSGTPVTSPAQAMAWGTGASAALEFPHGWGGL
VDLPAVPDE---ESVNALLVVL-AGTGEDQVAIRGTRRFAKRLRRKASSGP---AARPWRPRGTVLVTGGTGALGGHVARRLARQGAEHIVLAARRGPDA
PGA------AGLRDELEAAGARVTVAACDVADRDALRDLVERV-----GDIRAVFHTAGVIRETRLADTTPAEFAEVVAAKVAGAANIAELL--PDLDAF
VLFSSTAGVWGDGHGAAYAAGNAFLDALAAQHR-AQGRATTSVAWGIWAEGGMAALESVQRQRTLLGLGELDPGRALDALQDVLDHDVTLVVTEADWAQF
ARAYTH------------------A----RPSRLLRDL----------------------PEA------HSRPQAP------RPAPPAGGTDLLGLITTH
VAGVLGHERLDPRQAFKDLGFDSLTAVELRNRLTAALGVRLPPTLVFDHPTPARLAAHLSGESGEQDAP---
>tr|R1FXT7|R1FXT7_9PSEU Beta-ketoacyl synthase (Fragment) OS=Amycolatopsis vancoresmycina DSM 44592 GN=H480_33430 PE=4 SV=1
------------------QGLRSAWRRGEEFAEVELPDQ-PRLPFAWTGVTLHAG--VRL---TRRGADEVTVEPS-----------GAPV---ATVASL
VLRP-LPAGGLDGVDDLYDWTESQAEA-----DE-TGKPVHRVLGLVQEWLAAERPEVLVFVTTGAVAVHDGEAPDPDLAAAWGLVRSAQSEHPGRFAL-
LDTDD-PDH-------------PVIPAESQVAIRNGQSFVPRLARVTA--E---QTPDW-GDGAVLVTGASGVLGGLVARHLARHGVRNLVLLSRRGADA
PGA------AELAADLP----DAVFVAGDAADRDRLAEVLA-A-----HRITAVVHAAGVLDDGVVETLTPERLDAVLRPKAEAARHLDELTT--GLAAF
VLFSAAAGTTGGSGQGNYAAANAYLDALAQRRR-AAGQPAVSLAWGLWAEASGMTGDRARDRLGRSGVRPLESAQGLALFDRAVTAGPAAVPIALDAAAL
RRQAAE------------------G----TVSPLFRGL----------------------FPP------SAR----------------SEEALLDLVRTH
VAAVLGHRAIDPGRAFKDLGFDSLTAVDLRNRLAAATGLRLPATLVFDHPTPAVLAAHLAGRTGR---T---
>tr|A8CAC5|A8CAC5_9ACTN Polyketide synthase (Fragment) OS=Streptomyces eurythermus GN=angI PE=4 SV=1
------------------PAGVDAWRYKVVWKGLPTEET-ARLSGRWLLVLPEGDPGDTL---TRCGADLARVSTAD--------RAHFAELLAAHRRQD
EESG-NGEPAVRGVLSLLAL-------------SHAPSAVASSVPLVQAANDVGLGAPVWAVTQGAVAVIPGEVPDDMGARLRAFGRVAALELPEVWGGS
IDLPSAPPD---ERVLRRMVTVLADGAEDEVAIRSAGVYGRRVVR---PGG---ARTHWRPRGTVLVTGGTGALGGHVARWLAANGAEHLVLTSRRGQDA
PGA------AALTAELEARGVRVTVVACDVSDRAALAALLDDH------PPTAVFHTAGVLADGVIDGLSADGLALVSRPKADAAELLHELTADRDVDAF
VLFSSVTGVWGNGGQAAYAAANAALDALAERRR-ADGLPAISIAWGLWAGGGMAEGTGE-ESLVRRGIEAMDPVRAVEALQQALDRDDTCTVAAVDWERF
APSTDA------------------V----RATHLFSTV----------------------PEA------REALDTA------RRQRPARRHRLVELIRDE
AAAVLRHDAIGPDRAFKEVGFDSLTALELRNRVNAATGLSLPTTTAFDYPNPAALADHILSRLAD--LP---
>tr|A1YBT8|A1YBT8_SORCE JerE OS=Sorangium cellulosum GN=jerE PE=4 SV=1
------------------QSTADAWRYRVAWKPLAIDAR-SDLSGVWLFLAPPDAKDRAL---AESGATVVPVLDVD--------RALLSAR--LREQ--
---V-GDGGAIRGVISLLALDETSLPQ-----HDGLPRGLAFTLALVQALGDTAIAAPLWLLTRGAVSVGRSRLERPLQALTWGLGRVVALEHPERWGGL
IDLAGALDE---KALKRLVAALGGRDAEDQLALRPSGLFARRLVRAPLEAT---AVRAWKARGTALVTGGTGDLGAHVARWLAQNGAEHLVLTSRRGQDA
PGA------AELTAELTALGARVTIAACDSSDRQALAALLQRLRA-EGPPLRAVVHAAGVDQVTPLARTSLAEFAGIASGKVAGARHLDDLLGNAPLDAF
ILFSSVAGVWGSGFQGAYAAANAFLDALAEQRR-ALGSTATSIAWGLWGGKSMADDAAK-DHLSKRGVSPMPPQLAIAALQRALDHDETTTLADVNWSRF
APAFAA------------------A----RPRPLLHDL----------------------PEA------RSALESP------SPAPR-RVRHLVSLVLAE
TAVVLGHSRLDPHTGFADLGLDSLMAVEMRRRLQQATGVSLPATLTFDHPSPHHIATFLLDEVFADEAI---
>tr|K0K5J3|K0K5J3_SACES Putative polyketide synthase OS=Saccharothrix espanaensis (strain ATCC 51144 / DSM 44229 / JCM 9112 / NBRC 15066 / NRRL 15764) 
------------------RGLVAGWRSDVRHAEIALPAR-PRVPFAWAGVEVLDA--ARL---TPRPDGTVALLAG-----------GRPV---ATVDAL
TLRP-LTRPGPDGL---HDWRPVPVPD-----RPADRNPVHATLARLQRWLADDRPGPLVVHTRGAIAA-GGPPIDPAQAPVWGLVRSAQAEHPDRFVL-
VDGDGDPRL-------------AAGTGRPQVAIRAGALLVPRLTRAPG--D---TPPSW-SAGTVLVTGATGALGAALVRHLVDHGARDVVLLSRRGPDA
PGA------ADLAGP------GVRLLAVDVTDRDALARVVADL-----PDLRAVVHLAGVSDDRVLTDLTPEHLDTALGPKADAAWHLHDLTRDRDLTAF
VLYSSLAGVLGTAGQANYAAANTALDALAAHRA-AAGLPAVSIAWGLWEADSALSATADLARLERVGVRALSTSDGMALFDLAVAGTDPAAAARLDLA--
----AA------------------G----APGPATPGV----------------------LRT------AAA----------------RVRALRDLVRAE
AAAVLGHAGIADRKPFRDQGFDSLTAVELRNRVAAATGVRLPATVVFDHPDLAAFVAHLDRELAG---A---
>tr|B4VAJ6|B4VAJ6_9ACTN Polyketide synthase subunit (Fragment) OS=Streptomyces sp. Mg1 GN=SSAG_04835 PE=4 SV=1
------------------SGVQDGLSYEVTWKSLSLPES-VRLDGRWLLVVPEHDADHAL---TTHGATVSHLTATD--------RADLSAR--LTTT--
--AA-EEQEPLGGILSLLGWAEGAQVD-----RPTVPIAIATSLALVQAVGDAGFGVPVWAVTRGAVSVVPGEVPETAGAQLWALGRVAALELPDRWGGL
IDLPADADA---RTAGL---AVRIAAGEDQLAVRPSGAYGRRVVQAGHPTG---AKPEWRPRGTVLVTGGMGAIGTRVARWLARNGAEHLVLTGRRGAGT
PGA------DELAGELRASGVQVSLAACDVSDRAALAALIDAH------PPTAVFHTAGVLNDGTVDTLTPGRLDGVLGPKATAAVHLHELTAHLDLDAF
VLFASVTGVWGNGGQAAYAMANAALDALAEQRR-AGGLAATSISWGLWGGGGMAEGNGE-VSLNRRGIRALEPATGIEALQRTLDQDATCTVVDVDWSEF
TPRTAA------------------L----RRGRLFADL----------------------PEA------RRALGSE------GAAQEGQRRILVELVRAE
AAAVLRHELLAPRRSFKDAGFDSLTALELRNRLSTASGVVLPVTVVFDHPNPGALADFLYGEALGDQAD---
>tr|F1B9Q4|F1B9Q4_SORCE Polyketide synthase OS=Sorangium cellulosum GN=leuB PE=4 SV=1
-------------------------------------------GRAWLLLADATDVGEQLGAMLRHGQRPVVVTRGAEGAAIHGAGLRFDPGSADGFRSL
LRALDQHGLRPDGVVHLWSLDAVKGDDDTSELRYASRHGCQSALFLLQALVEAERPPGLWLVTGGSQAAREDTVDGVAHAGVWGLGRVIAREHPELSCRR
IDLDARPG---EADIRALFDEIQLRSQEDEVALRGGERYVPRVVRRAEAARVHGPGDALRADGTYVITGAFGGLGLRVAEWMVERGARNLGLLGRRPPGA
---EAAQVIERLA----QRGARVREILVDVAHEGRLASALAELQA-SMPPLRGVVHSVGAIDDGILQNLTWERFERVLAPKVEGAWNLHRLTRGMELDFF
VLFSSAVALLSAWGQANHTAANTFLDALSHHRR-ARGLPALTIDWGAWDQVGAAARPEADQKMRDLGMGTIPPDAGLRVLEQLLSEGAVQGVMPIDWSQF
ARKLR----------------W---------SPLVSE---VLS------------------DTGNEERAEPELLHRLEQ----AGPAQRRALLREHVREQ
IARVMHLSQISEQRRLFTMGLDSLMSVELKNNLSTSLGKPLRATLVFDFPTLGALVEHLSELLPGAE-----
>tr|A0A061A4A2|A0A061A4A2_9ACTN Beta-ketoacyl synthase OS=Streptomyces iranensis GN=SIRAN9186 PE=4 SV=1
-----------------QQETLAGWQYRVTWRRTEG-S-ERPLTGRWLVVVPADWLEQAIAALTARGAQVSRVTVP--------------VD--ADVEAL
CHELVLDGQRAGSVVSLLPLDTAGDT-----DAVSVSVGLRGTLALVRAVSTLGLSTPIWCVTQDAVAVRPGDVTQPRQAALWGFARHAGLEQPVPWGGV
VDLPREVGQA---DLAALAGAL--GDGESELAVRGGTVFCRRLTRVTAPAH----RTPQPLERSALVTGGTGALGAEVARWLVARGARHLVLASRRGPAA
PGA------AELAAELAEQGVSVSVVACDVAERAQLAELLDTWPA--EHPLTTVVHTAGVLDDGIIDRLTPERFERVFRPKVAAAWHLHELTRDHDLVDF
VLFSSFVGTVGPAGQANYAAANSSLDALAAHRR-ALGLTGTSIAWGLWQGPGLADRDGVERQLAARGLRAMDPRGAIQAMDQVIDRDETAVVADVEWSSF
ATELVGT------------------R----SVSLLAELLPA---------SGA---EPGGP---AEGADATGVRERLAGL----PATERAYTITELVRTT
VAAVLGHSSVESGRSFQEIGFDSLTALRLRNRLGAATGLQLPATLVFDYPTPASVAELVGSELF--------
>tr|J2JPY8|J2JPY8_9ACTN Beta-ketoacyl synthase (Fragment) OS=Streptomyces auratus AGR0001 GN=SU9_33853 PE=4 SV=1
-----------------EKSTVDSWRYTVRWTPLSERT-AAALHGTWLLVAPAAQVAAVQDALTAHGARVRLVDLA--------------PE--DGSERT
TGRLRA-DDDITGVLSLLPLDERAHP-----DHPAVPLGLSGTLALLQALGDLGIEAPLWCGTRGAVAIGRSEVTHAHQALVWGMGRVAALEHSDRWGGL
LDLPETLDKR---AADRLCALLAGPDGEDQIALRGSGAYGRRLVRAPLAGTP--AQRTWRPRGTVLVTGGTGAVGGHIARWLAREGAEHLLLTSRRGADA
PGA------AELEAELTALGSRVTFAACDVADRDALADLLATVPE--QHPLDAVMHVAGSLDDGVLDSLDPGRMDTVLRAKVTAALNLHELTRDRDLSAF
VLFSSTSGTISGPGLGNYAPGNAFLDALADRRR-ADGLPATAVAWGHWSGDGMGEGA-VGERLRRYGVYDMQPELACGALRQALDHDEAYSVTDLGWDKF
TPAFTAS------------------R----PSALLRDLPDA---------QRVLEAQESDD---T-GSDAAKLLQHLAGL----SESERAAMVLDVVRSY
VATVLGYSAVDPERAFSDLGFDSLSAVELRNGMNGITGLRLPATLVFDYPTCAVLADFLLAELS--------
>tr|D5UX39|D5UX39_TSUPD Acyl transferase OS=Tsukamurella paurometabola (strain ATCC 8368 / DSM 20162 / JCM 10117 / NBRC 16120 / NCTC 13040) GN=Tpau_347
-----------------VATDSGAWTEAAHGRLAPVDP-ARE----CP------S---------------------------------------------
--APTEPGISMRARYAEMAENGTVAL-----PEGVGVRGFSIHPALLDAALHTISATQIYDTVFEPPQELPDAGSEPEPRTFADIADGADPAASAAAGLW
RSAI-NEYPG---QFGIIRTALTLTSAEPNLAISDGTVRVPRLRPVSDTETA---SPARLDHGTVVITGASGTLGEALARHLREHRTPSLLLVSRRGADA
PGA------AALAEELAGLGTRAEFIAADVADADSVRAMLAHVPT--HAPLSAVVHAAGVLSDGVLSAMTPRRLAEVYRAKVDAVLTLHRATRHLDLDAF
VVYSSIAGVVGSAGQGNYASANAFLDAFARGPH-S-GGRTVSVAWGLWAEASMTSVLTDRERVSRAGLTGMSTADALALLDAALPARDGAIRSAFDTAQL
GELARSG------------------D----IQPVFRALAPG---------RRR------------EPVAPPSLAQRLTRV----AEEDRLELATDAVAEV
AATVLGYAELDTRRGLLELGFDSLTAIELRNRLGAATGLRLPATLIFDYPSAAAIAAYLIEQAV--------
>tr|A0A0N1K5V1|A0A0N1K5V1_9ACTN Polyketide synthase OS=Streptomyces sp. NRRL S-4 GN=ADK82_24130 PE=4 SV=1
-----------------EQTVLDSWRYRISWKPVAPAT-APAPSGTWLVVSPSGGEA-VTRELVRNGARTVQVLFE---------------S--DDTAMA
LQRLGADGGRIEGVLSFLAEDDRPDP-----FHPVVPAGVAATTSLIQAMTDLDLAAPLWCLTRGAVSVDGPGLTGPAQAQVWGLGRVIGLEHPDRWGGL
IDLPAEPDER---TAAQVCRLLTGAGDEDQLAVRPQGVFARRLGRSPAGPRPA-APTRWEPRGTALITGGMGALGSHVARWLASNGAEHLVLTGRRGEDT
PGA------LALKDELMALGARVTLTACDVADPDALTALVKELAQDDTAPVRAVVHAAGESLVSGLEESDPAEFARVMSAKAAGASSLDALFDSDSLDAF
VLFASGAGVWGGSAQGAYAVSNCHLDAVAERRR-ARGLAATSVAWGGWAGGGMVDAA-AGSTLTRMGLRPMEPEAAVRALVQAVERQETCTVADIDWDRF
APAFAMA------------------G----PRPLIEDIPEA---------AAALRPEDDRE---APEAAAGALAARLAGA----SDAERKRMLLDLVRAE
AAAVLGHDAVDPKRAFREMGFDSVMAVELRNRLNTATGLRLETTLVFDEPSPTGLRDRLMRELL--------
>tr|A0A0C1TI20|A0A0C1TI20_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces pluripotens GN=LK07_30850 PE=4 SV=1
-----------------AGTTDEPWTQHAAGTVEPQVG-AAPAQGDWP----------------------------------------------------
-----ETGPEVGELYRLLADRAEVEL-----PAPAEPGGFGVHPALLDAALHALAGVALYTVDYKPVPAGTDGEPAVTDPGEWLLVNGTDLGAAAVWGLV
RSAQS-ENPG---RIVLLPDPVALATREPQLTVRDGAVLVPRLVRGTA-GE----PAAWHPEGTVLITGGTGALGSVLARHLAEHGVRHLLLTSRRGPGT
PGA------AELVADLAALGATAKVAACDVADRDALAGLLAGIPAE-H-PLTAVVHAAGVLDDGMLAAQTLERVDRVFRPKVDAALHLHELTRGYDLSAF
VLFSSAAGILGSPGQSNYAAANAVLDGLAARRR-AAGLPAVSLAWGLWAGAGMGETVAAGRRIERLGVVPLDPAEGMRLFDAAVPGRTALVPVRLNLAAL
REQARTV------------------P----PAPVLRGLVRA---------PAR------------RVAGTGALAVAFAGL----DEAARGRLVRDTVRTA
VAAALGHAGLGDRRAFTDLGFDSLTSVELRNRLAAGTGLQLPATLAFDHPSIAATAEYLLGRLT--------
>tr|A0A0F2T6A1|A0A0F2T6A1_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces rubellomurinus GN=VM95_36995 PE=4 SV=1
------------------SATIDRWRYRIAWRPVPVPAA-PALSGRWLLLLPPAELAADCRDLAAHGAEPVPVPV--------------DAA-TADRAAL
GDALAAADRPVAGVLSLLGLDERPRAE-----QPLVPAGVAATAAAVLALDDAGIEAGLWSATSGAVRAEKDTVDHPVQAHVWGLGRVAALERPAHWAGL
VDLPAALDPRAAARLCAVLGGIEADGTEDQLAVRAGGVFARRLVRAPLDGAPAPAARPWRPRGTVLVTGGTGALGARVARALAARGAEHLLLTSRRGPTA
PGA--AELAEE----LTGLGARVTVTACDVADRAALAAVLAAVPSD--APLTAVVHTAGITQASPIDETGPAEHAAVVAGNSAGAAHLDDLLGDRELDAF
VLFSSNAGVWGSGGQGAYAGANAYLDALAEHRR-ARGRTATSVAWGAWDGGGTATDG-ATEQLRRRGVLAMDPEPALAALLQAVARDETFLVADVDWARF
VPGF------------------TAR----RRSPLLAELPEV-RAALGAAEQA--------P-----QPADSDLARRLADT----PPADHERILLDLVLTE
VAAALGHDALEAGRPFKDLGFDSLIAVDLRNRLRTAAGLPLPATLVFDHPTPTALARHLREEL---------
>tr|J1RWK2|J1RWK2_9ACTN Modular polyketide synthase (Fragment) OS=Streptomyces auratus AGR0001 GN=SU9_31533 PE=4 SV=1
------------------RGTADGWRYRVVWRPLTEPAA-RQLDGEWLVVVPAGYLVHGARELAEAGARTHSLTV-------------------DDRAGL
ADLLRPGPGPFAGVLSLLALDERPDRT-----HPCVPTGLSLTLALLQALGDAGIDAPLWCVTRGAVGIGEDAPTNPDQAGIWGLGRVAALEHPERWGGL
IDLPGRAGGQTAAQEVALLARILAGDDEDQLAVRGSALFGRRLLPAPVAG--KPPRRSWRPRGTVLVTGGTGALGAHIARWLAADGAEHLVLTGRRGADV
PGV--AALCSE----LRDQGVRVTVAGCDLADRQAVAELVRQIERDG-EPVRAVVHAAGVSALGSLAEAGPADLAAALAGKVAGADHLSSALDPAQLDAV
VYFSSISGTWGVADHGAYAAANALLDARAERGR-ADGLPVLSVAWGPWAGGGMIADS-IHDVLRRRGVPVIDPDTALTALQQALDHDDTSIVADVDWRRF
HSVF------------------TSV----RPSRLLTEIPQL-AADEDGDGPG--------DDGSDRGSARSPLAEKLAGL----DVRQRTAALLDLVREQ
VASVLGHAPVDPERPFKELGFDSLTAVELRNRLSRATGLRLPRTVVFDHPSPAALAGYVGTQL---------
>tr|A0A0N1K6E0|A0A0N1K6E0_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. NRRL S-4 GN=ADK82_26560 PE=4 SV=1
------------------DASDEAWTRHADWPPAGAR-A-VAVDTLYATLADAGYLFQGLRAWRQDGFGLHPALL--------------DAA-LVRREGS
GASLADGAGS--HVASVESLALRPVSE-----WSVKPVGVAQSA---------DRAEGSWAVVGEAEFLPVCDSPDPVQAAVWGLLRTAESENPGRFVLV
D-HD---------QEP-LLPA--VASGEPQAAVRAGEVLVPRLARVPLPV--GQIPAFVEPSGTVLVTGASGVLGGVVARHLVEHGVRHLLLLSRRGADA
PGA--ADLVAE----LAESGAQARFAACDVADRGALAEVLDSVGSE--HPLTGVVHTAGVLDDGVVSSLTPERLAAVLRPKVDAAWHLHELTRDMDLSMF
TLFSSAAGVFGGAGQANYAAANAFLDALAEVRR-AEGLAGQSLAWGLWAQAS-TGQL-DSGDLRRMARGGLTPLSSVQGLDLAGLADEAVLPIRVDMARL
RPEM------------------TPL----MLR-GLVRVPNR-RQAD---------------SG-TD--RSASFGRTLLAL----PEAEQRQLVQDLVRAQ
AVAVLGHEAVQPERAFTELGFDSLTAVELRNRMSAATGLRLPATLVFDYPTPFAMADYIRTEI---------
>tr|A0A0C2BI28|A0A0C2BI28_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. 150FB GN=QR77_03315 PE=4 SV=1
------------------RSTVDSWRYRVEWKALPTGEP-ATLAGHCLVLVPESGLADTVCRIEAAGATVTRTVL--------------TGA-DSDRQTL
A--RAEVPRPVGRVVSLLGLDESPHPD-----HPAVPVGVAVTLSLVQALGDAGIDAPLWCLTSGAVSTGHDPVTGVAQNLVWGLGRVAALEFPRRWGGL
CDLADGFDTNALIS------ALA-THGEDQVALRPDGAFGRRLARAPLPA--APVSETWRPRGTVLITGGTGAVGGQIAAWLAGNGAEHLVLASRQGGAA
PGA--AELTAE----LESLGARVTTAACDVTDRAQLAALIADIEAKG-DRIRSVMHTAGAGRLVPLPDTDLAEFGDTLHAKVLGAAHLDELIGE--VDAF
VLFSSISAVWGSADHGAYAAANAYLDGLAENRR-ARGLSATSVVWGIWAPQNMAADL-AEQQLLGRGIPFMRPALAIDGFQQVLDHDETVVVAAVDWDRF
APVF------------------TSA----RPSPLIADLTDA-RQALAGQSAG--------ADG-SEEGSSSPLLDRLRGL----SEAERREVLTDIVRTQ
AAAVLGHDEIEPGRAFRDLGFDSLTAVELRGRLNAATGLRLPVTVVFDYSSATALADHVRAEL---------
>tr|A0A0D0H9B8|A0A0D0H9B8_9BURK KY49.ctg7180000000020_quiver, whole genome shotgun sequence OS=Burkholderia sp. MSHR3999 GN=KY49_5819 PE=4 SV=1
-------------------APDANPLYHVVWEQQAALPAAAADASPWLIFADESGAGDRFAALLRRGASCALVRAGRDYRAPADAAWQVAPEQPDHFVRL
LKEAAA---PGQRIVFLWALDETVGA----------SRMSTALLHLVRALGSGEARPRIWVVTRDAVEAGEARVSGLAQAALAGLARGAMIEHPEWFGTA
IDLDPAAPE---DETQALLHEVLGESREEQVALRQGARYVARLSPLAQAET---AALPVDPEAAYLITGGFGALGLHTARWLAAHGAGTLILVGRQGAA-
-SDESQRAIAELR----ERNVTVRCERLDITDPAAVADCFAALRRER-VPLRGIVHAAGIVGYKPIMQVEREELEAVLQPKVAGAWLLHQHSEPFPLDFF
ILFSSIASAWGSRDQAHYSAANRFLDALAHHRR-HLGLPASSVNWGPWAQGGMTFPE-AEALLRRVGIRSLAADRALDVLDHLPAV--PQVVVDIDLALF
QG------------------SYEARGPKPFLDRV---------------------RVDATPPSA------PAMPALS-----DKSPRERKRLLADAIDRA
VAQVLGFATPDRDRGFFEMGMDSLMAVDLRAHLEKALGAPLSVALLFDHPTVNALADFLAEQSS--------
>tr|A0A0F5A3P8|A0A0F5A3P8_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. MUSC164 GN=VT50_35900 PE=4 SV=1
------------------RSVINSWRYQTTWKRLPTPSTRPDLSGTWLLIIPSGHVTTATQALTAHGATSLRVDTRA-----------------VDRDTL
ADQLTATEGAPAGVLSLLALDEEPHPQ-----YAAVPSGLTATTVLLQALGDAEIAAPLWCLTQGAVATPGSPLPGPRQAQTWGLGRAAALEHPRRWGGL
IDLPIVIDH---HTADRLAALLAPGGPEDQSAIRATGSYARRLRRAGTPTT---APRTWQPTGTTLITGGTGGLGAHIARWLARRGAPHLHLISRSGPDA
PGA------AQLSEELNVLGTTVTVTACDVSNRAALQHLLDTIPAE--HPLTTVVHAAGTSDTELIAELGPERLQGVLGPKALAAAHLHELTQGLDLSAF
VLFSSGAASWGGSRQGAYAAANTYLDALAEHRR-ARGLPATSIAWGPWGDAGMAADDTALAFYGRRGLSPLGPELAVASLQHALDHRDTTTVADIDWEKF
PTAFTA------------------QRP----SPLLDDLITAA------ENPT-----ERITEASATTSATTSLQQRLSA----TTPEQQHQLLRERIQSL
AASILGHDAIPPAQPFQELGFDSLTAVELRDQLATATGIDLAPSLVFDHPTPNALAAYLLAEL---------
>tr|M3D294|M3D294_9ACTN Type I polyketide synthase (Fragment) OS=Streptomyces gancidicus BKS 13-15 GN=H114_03364 PE=4 SV=1
------------------RATVDRWRYRVVWRTHDLPATR-TLDGTWLLAVPETHVAAVARTLSQAGATTVTADAGD-----------------LDRERV
AARLAAEPASVQGVVSLLALDERPAPG-----HPGATAGMTSSLVLLQGLLDADLDARLWILTSEAVTTTGDVVRNPLQGALWGFGRVVALEQPRRWGGL
VDLPAELDE---DTARGLVAVLAARSDEDQTALRGRTAHIRRLVRAPAGRP---APRAWRTSGAALVTGGTGGLGAHTARLLARKGAEHLVLTSRRGPDA
PGA------EALREELTALGCRVTIAACDVADRDALERLVAEVEAD--GPARTVVHTAGVGMLAPLAETDLDFFAEGARAKLLGAANLDAVFDHDRLDAF
VLYSSVAGTWGSGDHGAYSASNAYVDALADQRR-ARGLTGTSIAWGIWSPEGGGMAVVVREQLRWRGIPFMDSDLAVTGLEQALDHDDVFAVADIDWERF
VPVFTA------------------AHP----RPLLHEVPEVA------EAMK-----ADAPDEDTSADRLGGLRAELAA----LPAAERVRTLTDLVRTQ
VATALGHEEIAPQRAFRELGFDSLTAVELRNRLNAATGLSLPATVVFDFPNVNELVRHLLEHL---------
>tr|E3JCX3|E3JCX3_FRASU 6-deoxyerythronolide-B synthase OS=Frankia sp. (strain EuI1c) GN=FraEuI1c_3089 PE=4 SV=1
-----------------TRATIDNWRYRVAWRPVTPSPG--RVPGHWLLAAPADRDAPATQALVERGARVTTVRVGADVER---------AAVAAAIRSA
LAAADAPTERVAGVLSVLGLRSDLLPD----H-PSVPWGLGATVGLIQALHDLGLDTPVWLTTSGAVTTPGDAVREPEQAMVWGLGPVLAAENPAGFGGL
IDLPAEVDE---RAAARVADLLGGHHGETELAIRAGAVHARRLVRAPATETD---TATYTPTGTTLVTGATGAIGQHLARWLAHNGAPHLLLLSQRGPDH
PD--AARLTHDL----AQNGTHVTLLAGDIADPHHLTHALTHIPPN--APLTAIYHTAAILDDALTTDLTLTQINNTTRVKVDGARNLHHHT--HSLTHF
VLFSSMAGISGITGQGNYAPGNAYLDALAHHRR-HHHQPATSIGWTHWAKAGDGTGDAVETRLARRGLTLLPPAAALTALHHPLTHDTTHLIADLDWNAF
GRDQ--------------------------PGQLTAELRTAPAPR---SGTAST--EAARPGSA--RDAAGRLSEELATL----PPARRAARLRTLVRAE
ASAVLGHDRLEPTTSFRDLGFDSLTAVELCNRLRTASGLALPSTLIFDYPSPDSLAEYLAKRLALDA-----
>tr|E3JCX2|E3JCX2_FRASU 6-deoxyerythronolide-B synthase OS=Frankia sp. (strain EuI1c) GN=FraEuI1c_3088 PE=4 SV=1
-----------------TRATIDRWRYRIAWQRVAAEPA--PLTGDWLVTVPDELDAPWVRVLTGREASPVLVRVARDATD---------RALAGLV---
----KALTGPPRGVLSLLGLAEGSHPD----F-PSVPWGLAGTVGLIQALHDGDIPAPIWAVTRGAVTTANDPVTDPEAAMVWGLGSSAAAENPAGWGGL
IDLPGTIDQ---DSLQLLATAL-GQTDECDLAVRPGGLSVRRLVRAPMTEPD---ATPFTPTGTSLVTGATGAIGQHLARWLAHHGAPHLLLLSQRGPDH
PD--ADQLLKDL----TATGTQATLIAGDIADADHLTHALTHIPPN--APLTAIYHTAAILDDALTTDLTLTQINNTTRVKVDGARNLHHHTDTHNLTHF
VLFSSMAGISGITGQGNYAPGNAYLDALAHHRR-HHHQPATSIGWGHWAGG-------IEAQLARRGLTLLPPATALTALHHPLTHDTTHLIGDLDWDVL
WRDK--------------------------PDRLYRDLLRQPPAG-----PAAI--EPAAPTAA----PRQGLAGRLADL----PEAEGRRTVLRLVRAH
VAAIGGFDAVDVRVPFRDLGFDSVTAVELRNRLGNETGLRLATTLVFDHPSPAALAEHLFAELAPAA-----
>tr|E4NJF5|E4NJF5_KITSK Modular polyketide synthase BFAS5 OS=Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / 
-----------------LPLDVRGVALRAAWRTPDARPE--GLPFSWQRVALH-DDAPVLRP---DGPDAVTARITDPAGR---------TATVGVFHVG
WTPVAAPGPRPVTRWGLLGPRDERLP---------DPGAVHAVLDRVQAADDTTARTPLVVLTRDATGPARPRPADPGAAAVWGLLRAAQLEHPDRFVLL
-DTDGPDQDGLPGLGDALADLL--AGGEPQAALRGGVLYAPRLVRPPAPATA---PGAFGPAGGTVLVSGGGALAAVLARHLAAHGVRRLLVLSRRGADA
PG--LPELAAEL----AAAGAELTALGCDVSDRRALAAALATVPEE--HPLCAVVHTAGVLDDGLLDGLTAQRAAAVLRPKFDAAHHLDELTRGADLAAF
VVFSSAAGVLGSPGQASYAAANAALDALVAERR-RLGLPGLSLAWGPWARVSGMTAEADRRRIDRRGARGLSDEEAMALLDTVCAADGSPVLAHLDL---
GDGP--------------------------VHPMLRALVRRAPAG---AAA---------PTAA----A--ALRHRLDAA----ADGERERVLRELVLAE
AAGVLGHGALSATEPFLSVGFDSLTAVELRNRLAALTGVRLRPSAVFDSGTPAALAARLAAEARTED-----
>tr|C9YYI4|C9YYI4_STRSW Putative type I polyketide synthase OS=Streptomyces scabiei (strain 87.22) GN=SCAB_83931 PE=4 SV=1
-----------------ERLDLAGVHLRAAWRAGDALPE--SVPFSWHDVTVA-PADPVLRP-APQGGDAVAVRITDRTGR---------PVTVGLFRLD
WTRLPGGP--ATGTWATLGSSGGGLPA----L-AD-PEAARAALDLLPRAEPKFTETPLVLLTRGAVD-LAGVPADLGGAAAWGLLRTAQLEHPGRFVLL
-DTDGG---D--GLEAALATAL--AEGEPQLALRDGTLYAPRLVRPPVAGR-----AGFGPEGTVLVTGGTGILGGLVARHLTTQGVRRLLLLGRRGAAA
EG--MAALTEEL----SAAGAEVTVAACDVADREALAGCLAAIPPE--HPLRAVVHTAGVLDDGLVTALTPERLSAVLRPKADGAWNLHELTRDQDLTAF
VLFSSSAGVFGSPGQSAYAAANAFTDALAAARH-RAGLPGTSLAWGLWEQRTGLTDGGDLRRMARSGVRALPTEEGLALFDAALAGDDPVLPVGLDL---
PGGP--------------------------VPHLLRSLVRTPAVR---RRG---------PGTD----A--SLRPRLAAA----PE-EQGEILLRLVRTQ
AAEVLGHDALSEGDAFLESGFDSLTAVELRNRLAAALDLRLRPTAVLDSGTPARLAEHLRGELSRST-----
>tr|D7AWH7|D7AWH7_NOCDD Acyl transferase OS=Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488) GN=Ndas_0496 P
-----------------EPVPVDGYGLRAAWREGGRLPD--GHPFSWTGVRLY-AGADHLRP---VGPDEYALTMTDTDGN---------PLTAELYALE
WPTVDLDTGPL-PALAVLAPDTTGLEE----L-REVPEDAGASLELLQEADEGATDHRLIVVTRGAVAVPEEDVTDLVHAPLWGLLRSAQAEQPDRFTVV
-DLDGSD-----AAAATLTRAL--ASGEPQLALRGSTAHAPRFTRARVPGES---A---LGGGTVLVTGATGVLGSAVARRLERHGARDLLLLSRRGGGA
PG--ATALVEEL----TSLGARAAFAACDVSDADALAAVIDAVPEE--RPLRAVVHVAGGIDDGVLATLTPESLDAVMRPKADAAHHLHRLTEHLDLAAF
VLFSSAAGVLGSPGQANYAAANTFLDALAHHRR-SRGMAAQSLSWGLWERLGEAGSHEDISRLRRLGMRTLEQREALDLLNAALACGAPHLPLPLDLEGV
RTGQ--------------------------VPPLMRGLVRQPRYR---ASK---------GGAA----EGAGVSAAL-AA----STEERERLLLELVGAL
TTEVLGRESPDPDQDFLELGMDSLTAVELRNELRAATGLRLTASVVLAHSTPARLARHLAAELPEPG-----
>tr|M9T0Y1|M9T0Y1_9ACTN FscE OS=Streptomyces albus J1074 GN=XNR_5855 PE=4 SV=1
----------------------QEPVFRLDWTAAPAVKPTEGLTAAT-LGEDVFGVGTTLA---------------------------------SLTELT
GPDADPSAAPDFVLVPLAGAGDAAGAGDPDAPGADVPAATTRTLDLLQQWAERLGHSRLVFVTTGAVAADTETVRDLAAGAAWGLVRSAQSENPDRFV-L
LDLDGAD---APDTLRALLPDLPLGSGDAQFAVREGTALVGRLERLTTPGGRFLMPPRWNPEGTVLITGGTGALGGHLARRFARAGMRHLLLTSRRGADA
PGA------AELAAELRELGAEVTVAACDTADREATAALLDAVPA--AHPLTAVVHTAGILDDGVIASLTPERLAAVLRPKVDAAWHLHELTRDLDLAAF
LPFSSVAGVMGSPGQGNYAAANSFLDALTRHRR-HLGLAGTSLAWGPWAHDGGMTSTLDMRRMQSGGLPPLAVDQGLELFDIARGSDESFLLVGLAAGAM
RG-AAP-----------------------------------------EDLPPLFRSMVRSGRRTAASTDAAGASAALGAKLAGLGAAERVRYVTDLVREQ
AARVLGHKSVDVSQEFRELGVDSLTALELRNHLATATGLRLPATLVFDYPTPTALAEHFVAE----------
>tr|G2P0H2|G2P0H2_STRVO Acyl transferase OS=Streptomyces violaceusniger Tu 4113 GN=Strvi_6575 PE=4 SV=1
----------------------AGSVLTVDWSSTITLDDDP---APG-ADLQVVGA---------------------------------------PNDIV
LDDIDPA---AVVVL------------EAS-GSGDVPQSTGWVLTQVQRWDERCADGRLVVVTRGAVATPGERVGGLAASAVWGLVRSAQAENPGRIT-L
LDIDDQT---AQLDAGFVAR---AVSAEPQLVVRDGVVGAARLVRVAA------QEPVGFGEGRVLVTGGTGGLGREVARHLVAHGVRDLLLVSRGG---
-GG------ADLVAELEELGARAVVAACDVSDREALATLLEGVD------LSAVVHTAGVVEDSVVTSLDGARLDRVLAPKVDAGWYLHELTADRDLSAF
VVFSSLAGMLGSPGQGNYAAGNVFLDTLMEQRR-AQGLPGVSMAWGPWAQGAGLTSGLDMRRISQSGTPPFTVEQGLRMFDEALAVPRAAVVTRLDLGAL
RGR--------------------------------------------ADLPPLWRALTGKRAR-PAAADRRQDAGTLADRLAGLAIPERTEQLLVLVREH
VAAVLGYEHIDTNQAFRELGFDSLSALELRNRLQVATGLTIPATLVFDYPNSQRLATHLAGQ----------
>tr|D2X8Z6|D2X8Z6_SORCE EpoD OS=Sorangium cellulosum GN=epoD PE=4 SV=1
----------------------DDWFMEPAWEPTAVPGS-EVTAGRWLIGSG-GGLG-AALY--------------------------------SALTEA
GHSVVHAQAPTS-VVH-LGSLDERG--DAAPFDAALEESCDSVLWTVQAVAGFRDPPRLWLVTRGAQAIAGDV--SVAQAPLLGLGRVIALEHAELRCAR
IDLDPAR---CDGEVDELLAELLADDAEEEVAFRGGERRVARLVRRLPPDGRFILEDAIRADGTYLVTGGLGGLGLSVAGWLAEQGAGHLVLVGRSGAVS
AEQ------QTAVAALEAHGARVTVARADVADRAQIERILREVTAS-GMPLRGVVHAAGILDDGLLMQQTPARFRAVMAPKVRGALHLHALTREAPLSFF
VLYASGAGLLGSPGQGNYAAANTFLDALAHHRR-AQGLPALSIDWGLFADVGLAAGQQRGARLVTRGTRSLTPDEGLWALERLLDGDRTQAVMPFDWVEF
YPAAAS-----------------------------------------SR---RLSRLVTARRV---ASGRLAGDRDLLERLATAEAG-RAGMLQEVVRAQ
VSQVLRL-KLDVDAPLTSLGMDSLMGLELRNRIEAVLGITMPATLLWTYPTVAALSAHLASH----------
>tr|X2KS74|X2KS74_9DELT Phn2 OS=Nannocystis pusilla GN=phn2 PE=4 SV=1
----------------------RRWLYEQQWVLAERAAERRQQVGHWLLGSPVIAPLRVTTF--------------------------------ADS-IR
DPRALEAPAL-----EY-------A-------AADAIDRLEESLEPLRHLSRPGFPVQLSWLTQGCWLVPDDVPGAEGQAALWGLGKSCTAEHPEYGGRL
IDLPAGA---LLGEPSPT--------------------VIDHLVSSLLEDGIFL---RFRPDATYLVTGGLGGIGLALAEWLAERGACRLILVGRTPLPA
RIA------VDVIRRLERRGVSVQVAALDVANEAEVQRFLADHRDE-APAIRGVVHAAGVATGGPLRDMTATAFAQQLRPKLQAAWILQRALAEESLDFF
VLCSSAAALIPSPLVGAYAAANACLDALVERRR-RAGQSGLSIAFGPWAEVGMAAEYQARASTSPSTMTPMKTADALHLIGQLWQGTCGRPILPIDWSLW
QTRYRR-----------------------------------------LLEQPLFARFAAPAAADD---ADL----DPAADLASLPVAVQGQGLLAGLSRL
IQQVLGH-ELDVEKSFSELGVDSLMAFEAKEKIARVWSVDLPVLELLHAANIAELAQLVERR----------
>tr|G2G4P5|G2G4P5_9ACTN Modular polyketide synthase OS=Streptomyces zinciresistens K42 GN=SZN_02242 PE=4 SV=1
----------------------RDSLFTLDWTPVPAVDPAGAATARWAVGTDHYGLAAVSAY--------------------------------ADLDAL
GAAIDAGAAPEAVLVSYPGLDDEAAKGRAAKPVPEPADATHHTLGLIQGWDRRFDSSRLVFVTSGAMAPDREESPDLIHAPLWGMVRSAQSENPNCFV-L
VDLDPRE---PAEAS---KAALPLAGDEPQAVVREGTVLGQRMARVSSRGGRFLIPRTLDGPGTVLVTGGTGGLGALLARHLVEHGVGRLVLTSRRGVEA
PGA------AELVAELAGLGAEVRAVACDVADRASVEGLLAGIGS--EHPLSAVVHAAGVLDDGVVESLTPERVDRVLRPKVDAALHLHELTRDLDLAAF
ILYSSVSGTFGGSGQANYAAGNAFMDALAQHRR-AAGLPATSLVWGPWTQDGGMTTDLDVNRMTRTGMVALTPEAGLALFDATRDLDGAVLPMTMDMASV
G----------------------------------------------EHVPALLRGLVRAPARADAASTTADPATELKQHLAGKSATERERTLVDLVCDQ
VAVVLGYQAIDPGHAFKDLGFDSLSAVELRNRLNAITGTRLPATLVFDYPSPVALGRFLSEE----------
>tr|D0LS52|D0LS52_HALO1 Acyl transferase OS=Haliangium ochraceum (strain DSM 14365 / JCM 11303 / SMP-2) GN=Hoch_1182 PE=4 SV=1
-------------------LDIDDWLYELAWQRIDAEAEADDASARWLILADRGGVGEALAERVG-RSRCVLMYAGEAFQRSSERTITVAPAALDEFHAA
IAVLVEGGQAIGRIVHLWGLDIPSWDLDLEALERAQDLALTSVAFLVQSVAER-VSAPLWLVTRGSQSPEGAADLSVVQAAIWGMGRVIAQEHPALWGGL
VDLAPTGAGGAAAEAAALAEHLAHATPGEEVALRGEQRYQTRLVRAVASDE--TKPVSWRNDAAYVVTGGLGGIGAEVAAWMAERGARRLLLLSRSGVPP
RSEWETAERARLVRRLEQLGACVEVAALDVADEAAMRGYFERYQREGRPPIRGVVHAAATVSGRSMLTIDRASIAADLAAKVRGGWLIDRIFG-EQLDFA
VFFSSASVFFSSPFLGSYAAANAFLDALAHQRR-GRGRAGLSINWGFWEDVGLAARRALGAELAPKGMGSFTPEQGIEAMHRLLGRPRAVAVMPINWRTW
SAHHEAAA----------------------TAPLLAHLAATSSENH----A-------------EHAADEPGAIRLLDTLAEITETWRRLERLESFVRTQ
LGAVLRRDDIGRHTPLGSLGIDSLMALELRRGLERETGLTLPATLIWTYPTVAELAGFLSEQLVA-------
>tr|W7J718|W7J718_9PSEU Uncharacterized protein OS=Actinokineospora spheciospongiae GN=UO65_2903 PE=4 SV=1
-----------------GRQTIDGWLSRVSWRPVPDPAPIEGPLGRWLLFADRGGVAEELAARVAEGGHCHLVRTGPAYRAG-RWESTVVPGDPTHLSRL
AADLADGETGFEAVVHLWNLDLPGADALRAALD--PAAGAYSLITTAQSVLAGELTGRLHVVTRGTQAVRAEDPVEPIGARAWGISRVLWQELTAHRGVL
VDLEPGAPDRA-AEADALLRELAADPDVDEVALRGGVRHTSRLVPAADALT-APLPPRLRQDGAYLVTGAFGALGRLLCRTLVSRGARRLVLLGRTPLPE
RAWWDARFVRD----LEEAGAQVILAPIDVTDEAALTRWLAGYRRDHGLPLRGVFHLAGHVRDTLVPDMDRATFDAVHDPKVVGAWLLHRHLRDEPLDHF
VLFASVASLLTTAGQTNYAAGNAFLDALAHHRR-SRGLPALSLDWGPWA-TGMIEELGLEHYRVSRGMSSLSPEAGMAVLERVLGQEQAQLLVVVDWPTF
LS------------------WYA-DP-----PPLVAELAAA-----------------ATEVTETGG----SFLDVFR---V-ADDATRRELVAERFTAL
VAGVLRPEKVDQGAGLTSAGLDSLLAMELRAKVNTELKVSLPVVALLSGAPVAELVEQVHA-----------
>tr|A0A0M9YGN7|A0A0M9YGN7_9ACTN Polyketide synthase OS=Streptomyces sp. MMG1522 GN=ADK56_30120 PE=4 SV=1
-----------------ARTTIDSWLAEPVWTDCPPLPAATAPAHDWLLLADAGGTADAFAALAARGERCRLVRTGAAYTAS-GDGYTVDPASDADLRRL
FADLDRDGPFHGTVLHLWNLDAPALADCRPALR--DGAGAYSLIALARLLAARGAEGRLHIVTRGAQPALPGEGPEPLGAPAWGIGRVLRQELTGHPGKL
IDLDPGRRPGP-DEDRAEAALLAESDDEAEIALRDGVRRTSRLRPA-ENLT-RPLPPRLRPDGTYLVTGAFGALGRLLCRTLVRRGARRIVLIGRTPVPA
REKWAGALLRE----LEALGAQPVPATFDITDEDALAVWLDAHRRSGAPPVRGVFHLAGQVRDTLVADLDRAAFDSVHDPKTVGALLLHRHLRDEPLDHF
VLFASIASLLTTAGQTNYAAGNAFLDALAHHRR-ARGLPALSLDWGPWA-TGMIEELGLDHYLHSRGMSSLSPEAGMAVLERVIGQDHAQLVVVVDWPVF
LA------------------WYP-SP-----PPLVAELAAA-----------------AAPDAASGN----GFLDTFR---A-AGEEARRTLVAERFAAL
LAAVLRADRIDPATGLGDLGLDSLLAMELRARVHAELGVALPVVALLSGTPAGELAAQLHD-----------
>tr|W9G5B6|W9G5B6_STRFL Amino acid adenylationdomain-containing protein OS=Streptomyces roseosporus NRRL 11379 GN=SSIG_06681 PE=4 SV=1
------------------RTTIDSWLAEPVWTDCPPLPAEPPRDVSWLLLADTGGLADAFAALAARGERCRLVRRGAAYTAADGRTSTVDPASDADLRRL
FADLDRDGGPFGTVLHLWNLDAPALASDRTALGDHTGAGAYSLIVLARLLSARGAGGRLHIVTRGAQPALPGEAPEPLGAPAWGIGRVLRQELTDHPGKL
IDLDPRRHPGDRAEAEALLAEAL-SDDEAEIALRDGGRRTGRLRPAESLTR--PLPPRLRADGSYLVTGAFGALGRLLCRTLVRRGARRIVLVGRTPVPP
REKWAGRAVALLRE-LETLGAHPVPATFDITDEDALTGWLDAHRRSGAPPVRGVFHLAGQVRDTLVADLDRAAFDAVHGPKTVGAHLLHRHLRDEPLEHF
VLFASIASLLTTAGQTNYAAGNAFLDALAHHRR-AQGLPALSLDWGPWA-TGMIEELGLAHYLNSRGMSSLSPEAGMAVLERVIGQDHAQLVVAVDWPVF
LA------------------WYP-S-----PPPLVADLAA----AA--AP----------PADT---ASGNG---FLDTFRT-AGEEARRALVTERFAAL
AATVLGADRIDPATGLGELGLDSLLAMELRARIHAELGVALPVVALLSGSPTGELADRLHDG----------
>tr|A8M2E8|A8M2E8_SALAI Amino acid adenylation domain OS=Salinispora arenicola (strain CNS-205) GN=Sare_2407 PE=4 SV=1
------------------IGTIDGWLAEPAWVPLPPLAEPTPAGARWLILADGTGLAEEFAGLVAHGGQCHLVRPGTALHVVSAGRSTVRPDSAEDLRHV
LAG----SGGPGHILHLWNLDLPDFGETAMDLPHCGTLGAYSLIALAQALSGQKTGGRLHVVTRGSQAVDGSGVTQPTGAPAWGVARVLRQELPGHCGKI
VDLGVPSHT---AEAAELWREFA-HDDEDEIALRGGDRFTCRLRPAVELHR--PLPLRLRPDGAYLVTGAFGALGRLLCRTLVRRGARRLVLVGRTPMPP
RERWDRERIAFLTE-LETLGCQPLVAQVDVTDEHALTLWLGEYRRRRSAPIRGVFHLAGQVRDTRVERMDRETFDAAYDPKVAGAYLLHWHLRDEPLDHF
VLFASIASLLTTAGQANYAAGNAFLDALAHHRR-ASGRTALSLDWGPWA-TGMIEELGLVHYRNNRGMSSLSPNTGMAVLERVAGESRPQLIVAVNWPTF
LS------------------WYE-R-----PPALVTELAA----TT--AS----------PADA---A-HSS---FLEEFRD-AGEDDRHRLLSERFVAV
VADVLPVETVDRSAGVTALGLDSLLAMELRARISAELHVALPVVALLSGVSVTDLIGQVHEG----------
>tr|A0A087NRY0|A0A087NRY0_BURPY Amino acid adenylation protein OS=Burkholderia pyrrocinia GN=JM78_19285 PE=4 SV=1
-------------------APTAPPLYHVVWEPQAALPAAAADASPWLIFADESGVGERLAALLERGASCSLVRPGLDFGVGAEAGRQIAPERPDDFVRL
LNETAA---PGQRIVFLWALDEVVGE----------TRMSTALLHLVHALVGSETRPRIRVVTRDAVEAGEAPVSGFAQAALSGLARGAMIEHPEWFETA
IDLDPAAPE---DETQALLQEMLGESREEQVALRHGARHVARLSPLAQAET---AALRVDPDAAYLITGGFGALGLHTARWLAARGAGTLILVGRQGAA-
-SDESQRAIAELRE----RNVSLRCERVDIADPVAVTDFFAALRR-DGVPLRGIVHAAGIVGYKPIMQVGREELDAVLQPKVAGAWLLHQQSEHFPLDFF
ILFSSIASAWGSREQAHYSAANRFLDALAHHRR-SRGLPALSVNWGPWAQGGMTFPD-AEALLRRVGIRSLAADRALDVLDHLPAV--PQVVVDIDLALF
QGS------------------YEARGPKPFLDRV----------RVGGSPPR-A---PAMPA-------------L----S-DASPRERKRLLADSIDRA
VAQVLGYGTLDRDLGFFEMGMDSLMALDVRTHLEKALGIPLSVALLFDHPTVNALADFLAEQSS--------
>tr|A0A060ZF29|A0A060ZF29_9ACTN Modular polyketide synthase OS=Streptomyces iranensis GN=SIRAN1399 PE=4 SV=1
-------------------SVLDSWRYHVTWKPLGDALTSSSAGATWLIAAPAGEEGPRVAEARERGAQVVELTEADAV-----------------REAL
ARRLGEATTPPTAVLSLLALVEDLY-----RAGTAQPLGLALNLALLQALGDTGADVPVWYATRGAVSVGRDALDHPLQALSWGLGRIAAVEYPRRRGGL
VDLPGTLDD---RAVARLCGVLGRLTDEDQVAVRASGVHGRRLVRASAAAD---AIAPWRPRGTVLVTGGTGGLGAHVARWLARGGAEHLVLTSRRGPDA
PGA------AELADEIRESGVRVTVAACDAADREALAGLLATLDAD-EAPLDAVVHTAGVLDDGVLDALTPERADGVLRPKVDAALHLHELTRDRELSAF
VLFSSFAGTLGGPGQGSYAAANAFLDALAHARR-AQGLPATSVAWGAWSGGGLVDEA-VEARLRANGMPVMAPDLAITALQRALDVADTHVVADVEWDRL
IAATPSLD----------------------GAAVLGELPD--------ARRAE----AAAA--TAGERD-TPLAQRLAGL----SPQEAEEALADLVSTE
VAAALGYSAVEAGRAFRELGFDSLTAVDLRNRLNAATGLRLPVTLVFDYPTVTALVRFLLAES---------
>tr|A0A0N1K131|A0A0N1K131_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. NRRL F-6602 GN=ADL27_53860 PE=4 SV=1
-------------------AELDSWRYDIQWQPLPQAAAPRIDGARWLLLVPAGGVSEHVSQATALGAEVTEVEHAERA-------------------EL
AARLREIG-GCTGVLSLLALGDDPTDPGDFDQSDFDQAEFDRAVLVVQALGDAGSTAPLWFATRGAVRVGSDRSADPRQALLWGLGRIAALEYPQRIGGL
VDLPAEPDE---RAAERLARALGAPDGEDQLAVRAGGVYVRRLARKPLGLT---PVRNWRPTGTVLVTGGTGGIGAEIAAWLASNGARHLLLAGRRGDRA
PGA------AELAERLTGLGARVTIAACDVADREALRGLLAGIDP--EHPLTAVVHAAAVLDDCLLDVLTPERARSVLLPKVAAARHLHELTEGADLDAF
VLFSSIAGTLGGPGQGSYAAANAYLDALALARR-AAGLPATSLAWGAWDRVGLATGE-TGEWLSRNGIVAMEPEAALSAMRQAVDHDLPHLVADIDWAVF
GPACTPGR----------------------SGRVLEGLPE--------ARPAV----GRAP--DEEQVV-GGFAADLAGR----SPAERQQALLTLVRGQ
AAAVLGLDAVDLDRALRDLGFDSLTAVELRNRLNAATGLRLPVTVVFDHNTASRLAGHLSEQL---------
>tr|A0A0J5XC65|A0A0J5XC65_BURCE Amino acid adenylation protein OS=Burkholderia cepacia GN=VL15_08545 PE=4 SV=1
-------------------TPATPPLYHVVWEQQAALPTAAADASPWLIFADESGVGERLAALLRHGASCALVRPGRDYGGGAEAGWQVAPEQPDHFVRL
LNETAA---PGQRIVFLWALDEAVGAS----------RMSTALLHLVHARAGSSIGPRISVVTRDAVEAGEARVTGLAQAALSGLARGAMIEHPEWFRTA
IDLDPAAPA---GETQALLQELLGEHREEQVALRRDVRHVARLRPLAQADT---AALRVDPDAAYLITGGFGALGLHTARWLAARGAGTLILVGRQGAA-
-SDESRRAIDELRE----RNVSLRCERLDIADPVAVADFFAALRR-DGVLLRGIVHAAGIVGYKPIVQVERAELDAVLEPKVAGAWLLHQHSAPFPLDFF
ILFSSIASAWGSRDQAHYSAANRFLDALAHHRR-ALGLPALSVNWGPWAQGGMTFPE-AEALLRRVGIRSLAADRALDLLDHLPAVPQA-AVVDIDLALF
QA------------------SYDARGPRPFLDRV----------RV--------------TGTAAGA---QAMPA----LRN-ASPRERKRLLADSIDRA
VAQVLGYETLDRNLGFFEMGMDSLMALDVRTLVETALGIPLPVALLFDHPTVNALADFLADQS---------
>tr|A0A0F2T8G9|A0A0F2T8G9_9ACTN Polyketide synthase OS=Streptomyces rubellomurinus GN=VM95_35935 PE=4 SV=1
------------------RAQLDSWRYRIAWRRRADPATAPRLTGHWLLVAPTGEPTADVEELTARGAAVTALAVD--------------TASTADRAAL
ADAAAEAGVPVAGVLSLLALAEAPHPA-----HPAVPAGFPATVALIQAVGDADLGAPLWCATRGGVTVGGDRLGNPFQALYWGLGQVASMEHPKLWGGL
VDLPATGCGPA--ELGRLAAVLAEGGGEDQTAVRADGVHLRRIVRAPLTGRP--PARPWAPTGTVLITGGTGGLGAQTARWLARNGAPRLLLASRRGPDA
PGA--AELHAE----LTALGAETVIARCDVADRAALAALLAGIPA--EQPLTAVVHTAAILDDAVIDRLTPEQVDRVLRVKAHGALHLHELTRGLDLAAF
VVFSSFAATFGAPGLANYAPGNAFLEALAEQRR-ADGLPATAIAWGTWAGGGMAADG-IGERARRHGLHEMDPDLATEALGDALAHDETSVVIDVRWERF
AAVFASE------------------R----TGRLLDEIPEARK-AVESA--------ERDP--AADAAAPADLRRRLAGA----PEVERDRILLELVRSH
VAAVLGHRAVAPARPFRDLGFDSLTGVELRNRLGSATGLRLPATLVFDHPTPAAMARHLRGELLAD------
>tr|A0A0N9I194|A0A0N9I194_9PSEU Uncharacterized protein OS=Kibdelosporangium phytohabitans GN=AOZ06_39630 PE=4 SV=1
------------------RPSAQRLRYDVRWQPVTPG--PVGITGTWLVLTPTADVT--WLGLRQHGAEVVQVAAD--------------PTEYE---EL
AAETSARPDGFTGVVSMLALDAHEHGA-----Q--------RASAVLLALREAEIDAPFWAVTRNAVP--GGTVPDPRQAEVWGWGRVAALESPLGWGGL
VDLPTDADTGA--ESGGLLAAVLAGTGEDQVAIRSTGVLACRLVRTPSVA-----NVVTTITGTALVASGDDALGRQIASWLEDAGAERVVLTGATAQDD
LA-----------------------------------ALLKDLGD--GTPVSTVVHAPGPVDLTPLADLAPEQLGAAVSRQLDGVAQLDDLLD-KESVRL
VLFSSVAGVWGGSGHGAVAASAAHVAAVAERRR-ARGLPTTAIAWGPWDRDESS------AQIRRSGVLPLRGDDVFAVLRQALDADTALVAVDVDWPRF
ADLFTVA------------------R----PSPLIDGLLDADQ-PD-----------------PQDTPGSGDFVARLSGF----DAETRHHELVELVCKH
TAVVLGHTAVDPAKAFRDLGFESMNAVELRNNLNAATGLRLPATAVFDHPAPVVLARHIHAELFEA------
>tr|A0A0F4J543|A0A0F4J543_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces katrae GN=VR44_26260 PE=4 SV=1
------------------RSAADGRRYGVAWRPVRDE-ARPALRGTWLLAVPEGGAGARVRELLGRGAEVTLLPVG--------------PDAGPE--EL
AGALAGAG-RPEGVLSLLGLASGSHPE-----HPEVPAALAGTLALVRALGQAGVEAPLWVATRSAVATAGDPAPVPEQAQLWGFGAVAGLEHPDRWGGL
VDLPEELDGPA---LRRLSGVLAAGEGEDQVAVRASGVLGRRLVRTA---GG--DGAPWRPRGTVLVTGGTGALGARFARWLAANGAGRLVLTSRRGPDA
PGA--AELVAE----LGELGVPATIHACDAADRAALEAVLATVPA--DEPLTAVLHTAGALGDAVIESLTPAGLAGVLRPKVTAALHLHELTKGMELDAF
VLFSSVMGVVGNGGQAAYAAANASLDALAGLRR-AQGLPATSVAWGVWDGGGMAG-A-AGEHTRRAGFPGMPAEQAVRALAPVVAGAQAPVVADIDWEVF
TPRHAAG------------------R----PAPLLAEIAEART-ALAAA--------RTAA--AG---DRPELASALAGL----TAAEQHRTVLDLVRAQ
AAVVLGHEAVAPGRAFKEAGFDSLTVVQMRNRLAAATGLRLPTTLLFDNPTPNALAAFLRTQLVDD------
>tr|A0A066YH08|A0A066YH08_9ACTN Polyketide synthase OS=Kitasatospora cheerisanensis KCTC 2395 GN=KCH_74030 PE=4 SV=1
-------------------AAIDGWLAEPVWTDLPADTGDAPPPDRLLVLADAHGLAEQLARQRERGGHCHLVRPGAAYR-HGPDGSTVRPGSADDLRRL
FADLDE---GYDTVLHLWNLDLPSIDTGREQLTDCGTLGGYSLVALAQVLPSARPNGRLHIVTRGAQAVEDGDPVEPLGAPAWGVGRVLQQELVGHRGKL
IDLAGTAEHPASAEAAALLRELAV-EDAEEIALRGPRRATCRLARPALTR---PLPLRLRADGSYLVTGAFGALGRLLCRTLVKRGARRLILAGRTALPP
REQWADRRVAFLRE-LEELGAQAVPVPLDVTDETALADWLADHRRRQLPPVRGVFHLAGQVRDALVPELDRELFDAAYEPKVVGARNLHRQLRGEPLDHF
VLFASIASVLTTAGQANYAAGNAFLDALAHHRR-ARGLPALSIDWGPWA-TGMIEELGLVHYREARGMSSLPPAAGMAVLERVIGQDRAQLLVVVDWPVF
QA------------------WYATP------PALVAELAAAAE-TV-----------QAAP---AG-----GFPAAFR----AADPDARRQLVAERFTEL
VAGVLRPERIDPAAGLNGLGLDSLLAMELRARIHAEMGVSLPVVTLLSGDRVGELIERVH------------
>tr|A0A0C2BEW6|A0A0C2BEW6_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. 150FB GN=QR77_03295 PE=4 SV=1
-------------------ISTDAWRYRVTWRTGTPAS--QPLPATWLVVVPEGWAAGAVRALTARGAQVVEHVVSAD----------------TDRERL
AAALAE-QPRPDGVLSLLALAEQPHPH-----HPGLTTGLALTTLLTQALGDARWAVPLWCLTQGATSAFGGEVHHPAQAAVWGLGRVIGLEHPEFWGGL
VDLPAEYDE---RSAATLCDVLADGGDEDQWAVRAGTARVRRLSRAQAEGT--PARRAWRPNGTVLVTGATGAVGPYIARWLSGAGAGHLVLAGRRGADV
P------GAAELAAELAVSGTRLDHAVCDVTDREAVAGLVERLAA-DGTPVRVVVHAAALIQIASLAATSLTEFEDVVHAKTAGAVHLAELLP--DLDAF
VLFSSIAGVWGSGDHGAYAAANAFLDAYAEHLR-GRGVPATSLAWGIWDTPNLAETALDMDRVRRQGLPFIAPDLAVTALQRAMDDDEAFLVADVDWARF
APV------------------FTSAR----PRPLLDE--------V----PE------VAALSR------QEVPAV-APV----TAALSEAELVTLVREQ
VAAVLGHAAIDPKRAFRDIGFDSLTAVELRNRLNAETGLRLPTTVVFDHPTVQAIARHLRAEL---------
>tr|M3C265|M3C265_9ACTN Type I polyketide synthase (Fragment) OS=Streptomyces gancidicus BKS 13-15 GN=H114_04122 PE=4 SV=1
-------------------GLVDGWRHRVEWRALPAPNSAAAIDGTWLLVVPAAAATAVRAALENRGVRTLTLTVASDD---------------MDREAL
LALLNG-AGTVTTVLSLLSLDTRPQPD-----RPAVPQGLAGSLALVQALGDAGIGAPLWCVTQGAVGVGPEAPTAPVQAGVWGLGRAAALEHPKRWGGL
VDLPAVATL---RTLAVLPDVLAAGGEEDQVALREGKAYGRRLVHAPTGCK--TPARVWKARGTVLVTGGTGALGAHVARWLTDNGAEHVVLTGRTGD-G
P------HVEELRTEVQSRGTRLTVAACDMADREAVAGLVARLAE-DGTPVRSVVHAAGVSALGPVADAGPEDLEATLSGKVLGAEHLDAVLDPAQLDAV
VYFSSISGTWGVADHAAYAAANAILDARAERRR-ADGAPVLSVAWGPWAGGGMIA--SVQGDLARRGVPVIEPATAITGLQQALDHDDTFVVADVDWRRF
AEV------------------FTSVR----GSALLRE--------L----PD------AATTTD------AGLREI-AAL----DPARRPAALRALVSTA
VAAVLGHDALGDETAFKDMGFDSLTAVALRDRLNRATALTLPTTVVFDHPSITALAACIEERA---------
>tr|A0A086GID2|A0A086GID2_STRSC Polyketide synthase (Fragment) OS=Streptomyces scabiei GN=IQ62_43650 PE=4 SV=1
-------------------GRIDGWRYRVEWRALPAPTR-AATGGTWLLAVPAPSVTETVAALEARGARAAVVIVDADH---------------LSRSGL
GALLTS-VGAFTGVLSLLALDERPHPQ-----RAAVPLGLAATLTLVQALGDTDIEAPLWCVTRGAVGCGRGAPTAPAQAGVWGLGRAAALEHPKRWGGL
VDLPATGPD---RGVDLLLDVIAAGTQEDQVALRGGTAYGRRLVQAATGGK--AAARDWKPRGTVLVTGGTGALGAHVARWLAARGAEHLVLTGRHGE-G
R------HLDDLRRELTPYGTRLTVAACDTADREALADLVTRLAD-EGGPVRSVVHAAGVSVLGPVAETDVEDLSATLSGKVLGADHLDDVLDAAQLDAV
VYFSSISGTWGVADHAAYGAANAILDARAERRR-ADGAPVLSVAWGPWAGGGMIA--TVQDDLRRRGVPVIEPAAAITGLQQALDHDDTAVVADVDWRRF
AEV------------------FTSVR----GSALLTE--------L----SG------LRPATP--------LREI-GGL----EPARRTAALRTLVSTH
VAAALGHAGVSAEAAFKELGFDSLTAVALRDRLQRATGLKLPTTVVFDHPSISALAVHLDDRA---------
>tr|G2GPA3|G2GPA3_9ACTN Putative type-I PKS (Fragment) OS=Streptomyces zinciresistens K42 GN=SZN_36804 PE=4 SV=1
-------------------SVIDSWRYKTAWRPVSGTSV-PVLSGTWIVVVPES-VGDDLVRMLARGADAVTLTV--------------TEEDA-DRTRL
AGRVQAGRHDLRGVLSLWAFDEKPTET-----QPLVSAGLAGTVSLVQALRDLDATAPLWCLTRGAVATGPSTLTSAVQAQVWGVGRVAALEQSGVWGGL
VDLPDTPDE---RALRRLCGILAEPAGEDQLAVRAGGVVARRMVRASLGRTA--PARRWRPDGTVLITGGLGALGAHVARWLAREGAPHLVLTSRRGGDA
PGA------DDLARELTGLGARVTVAACDIADRDAVEALVTGLADQ-GDPVRAVMHAAVQAELAPLADATPDHFAALLGAKVAGAEHLDSLLGE-DVDAF
VLFSSIAGFWGSGDHAAYAAANAHLDALAERRR-ARGLAATSIAWGIWDAYDWDSLSTITDRAVQQGLPLLDPEAACTGLRQALDHDETFVIADIAWEPF
ATL------------------FTSV----RPSALIREIPEATA-------------PDSAAPGDTTGHDAATLLRRLEGLP----REDRERELVDLVRFQ
AAAVLGHDQVGLDRAFRDLGFDSLTAVDLRNRLKAATGERLSATVVFDHPTPAELAAHLHDRCF--------
>tr|A0A0N0GUJ5|A0A0N0GUJ5_9ACTN Polyketide synthase (Fragment) OS=Streptomyces chattanoogensis GN=ADL29_40220 PE=4 SV=1
-------------------AAVDSWRYEVTWRRSDDVKS-PSLEGTWLMVAEPG-TGER---ALAFGATVVPVDW--------------RPADT-DRAAL
AARLHAADGRIRGVLSLLGAEETSHPD-----SPAVPSGLAGTLTLVQALGDAELDAPLWILTDNAVQVTATPAPSPAQAQLWGLGRVIGLEHAARWGGL
VDVPRDLDD---RTAARLAAVLAADGDEDQIALRTDGAWLRRLAHAR-PAAG--PARSWTPRGTVLVTGGTGALGAQVARWLAAHGAEHLVLTSRRGEAA
PGA------PALRDELTALGSRVTLAACDVADRDALAALLAGIPAD--CPLTAVVHTAGVADVLALDDSGLADLAYAAEGKVTGARNLDELLGDTPLDAF
VLFSSNAGVWGGGGQGAYAAANAALDALAGQRR-ARGLTATSIAWGLWAGDGLADPG-GQDYVLRRGLRPMAASTAVKALVHAVEHEDTFVVADVDWERF
APA------------------FTAS----RPRPLIADLPEVRK-------------LTADPE---PSGETTALAARLREVA----EADRADVVLALVREH
AAAVLGHSAIAPRRAFRDLGFDSLTAVEIRNRIGAATGLRLPATLVFDYPSAADVAEYLLAQVA--------
>tr|A0A0B5IHG1|A0A0B5IHG1_9ACTN Polyketide synthase OS=Streptomyces vietnamensis GN=SVTN_37280 PE=4 SV=1
-------------------------------------------APDLVVFADEGGLGARLAEAVARGGRCRLVRPGSRYRSGA--HVTVRPDSAADLRRL
FDELG----SFGAVVHLWNLDLPPLDVGAADLDGIGTLGGYSLVPLAQVLPEACPEGRLHIVTRGAQAVVPGEPVEPFGAPAWGIGRVLWQELTGHSGKL
IDLDPAGGPG----AEALLRALA-DDGECEIALRSGRRHLSRLRPPVGLTR--PLPLRLRADGAYLVTGAFGALGRLLCRTLVRRGARRLVLLGRTGVPE
RGAWRRRRVAFLR-ELEALGAEVLVAAVDVTDTAAMEGWLAGRRAAGLPPVRGVFHLAGQVRDVLLPSLDREAFDAGYGPKVHGGYLLHRLLREEPVEHF
VLFASVASLLTTAGQVNYSAGNAFLDALAHHRR-ALGLPALSLDWGPWA-TGMIEELGLAHYRDARGMSSLAPEAGMAVLERVIGQDRAQLLVVVDWPVF
LS------------------WYPT------PPPLVSALAAA----A-------------AREVPAGQ--GGGL---LDAFR-AADEPARTALVTERFAAL
AAGVLRPELVDADARLGSLGLDSLLAMELRVRVHAELGVSLPVVALLSNGPVSELTERLHAG----------
>tr|A0A014MLM7|A0A014MLM7_9ACTN Polyketide synthase OS=Streptomyces sp. PRh5 GN=Z951_41235 PE=4 SV=1
-----------------EQSTVDGWRYRVTWKPLADSQS-ARLTGTWLVVAPDTADTDAVAVLAERGADVTRIAVDTG----------ADGRD-ELTERL
RAALATDGIPFTGVLSLLALDGRPHPRH-----SSVPAGVAAQLALVQALGDAEIGAPLWSATQGAVSVGRDPLDSPEQALVWGLGRVAALEHGERWGGL
VDLPGAPDE---RALARLVTVLAGAEEEDQVAVRATGLLVRRLVRAPLAGAP--AVRAWKPSGTTLVTGGTGALGAHVARWLAGNGAEHLVLTSRRGLDA
PGA------ADLRSELTELGAKVTVAACDVADRAQVEALLADIPAE--HPLTAVVHTAAVLDDGVIEGLTPDQVDRVLKVKVDATRHLHELTRDLDLSAF
VLFSSFAATFGAPGQGNYAPGNAFLDAFAEHRR-AQGLPATSLAWGPWGEGGMAEGG-VGDRMRRHGVIEMAPRSAVTALQHALDRDESVLVVDMEWKRF
VLAFTS------------------GRS----RPLLHDLPEA-RD---------VIQDMAGDAEADGA-GAVALAQQLAG----VPEAEQERLVLELVRTA
VAAVLGYDDVEAGRAFKELGFDSLTAVELRNRLSAASGLKLPPTLIFDYPTPTVLARQLRTEI---------
>tr|A0A0A8EKB2|A0A0A8EKB2_9ACTN Type I polyketide synthase OS=Streptomyces sp. 769 GN=GZL_03707 PE=4 SV=1
-----------------DKSTVDSWRYRIGWQRLPEPAS-AALSGNWLVVLPTGGAGTAAVALEAAGAEVTEVELPAE----------TDPG--------
-AVAELSGAAPEGVLSLVALEGTP-------------VGAANTVSLLQALGTAGIDAPLWCATRGAVAVASEGPDSPVQAQVWGLGRVAALEHPQRWGGL
IDLPVDADD---AARRRLVGVLAGAGDEDQLAVRAAGLYGRRLEHAPLADRA--PSRAWRPSGTVLVTGGTGPLAAQAARWLAENGAEHVLLAGPVEGVA
GGE------AALEAELANAGARVTIVPCESDDRATLEKLLATP-------PTAVVHAPTVLDQAPLAETTPAEFAAVVDAKAAMAAHLDELLDAHAPAVV
VFFSAVAGVWGSGRQGAYAAGNAYLDALAQRRR-ARGLPTTSVAWSPWDGGADTEDG-FLDFLRRRGLRAIDPALAITALQQVIDHDETFVLADVDWERF
VAGFTA------------------VRP----SPLIAGLPEV-RR---------IQAEE---GETAGA-EGSVLAQRLAG----KTDLERDRIVLELVRDQ
VAAVLGHEAVEVGRAFLELGFDSLTAVDLRNRLNAATGLKLPATLIFDYPTATALADYLKTEV---------
>tr|A0A0B4ZT44|A0A0B4ZT44_9ACTN IkaA OS=Streptomyces sp. ZJ306 PE=4 SV=1
------------------LSTIDSWLTELSWVPRPLPEAPLPAAGRHVLFADAGGVARRLAALIEAGGEVLLVRPGAAYGLDSARTATVVPGSADDLRRL
LADLGPVD----GVVHLWNLDRPALADPRGRFADIASTGAYALIALTQALLADHGGTPVHIVTRAAQCVLPGEPVEPLGAPAWGIGRVLWQELAGRGGKL
IDLAADGDIE--EDASALLRELADAEREDEIALRAGERHTSRLVAAEGLSR--PLPLRLRPDGSYLVTGAFGALGRLLCRTLVRRGARRLILVGRTRLPE
RERWADRHVAFLK-ELEALGAQPILAPLDITDEDALAGWLAGYRRAQGPPIRGVFHLAGQVRDTLVPEMDREVFDAVHDPKVVGAALLHRQLSGEPLEHF
VLFASVAAWLTTAGQTNYAAGNAFLDALAHHRR-AQGLPALALDWGPWA-TGMIEELGLDHYRNSRGMSSLAPEAGMAVLERVIGQDRAQLLVVVDWPVF
MS------------------WYA-S-----PPRLVTELAAT----------------AQGPGSE---GDG-SF---LDAFR-ETTADKRRLLLTERFTTL
VAGVLRAEQVDPAVSLNLLGLDSLLAMELRARVVAEVGIALPVVALLSSAPAGDLITQLHE-----------
>tr|A0A0H5B6C1|A0A0H5B6C1_BLAVI Malonyl CoA-acyl carrier protein transacylase OS=Blastochloris viridis GN=BV133_122 PE=4 SV=1
---------------------LTQALYQIEWIEGETFPLISSLPKSYLIFVESY-LTEKLADLSKQGHNVYLVYQGKEYRQQ-NNCFWLGNK-QEDYQLL
WQSLDNRAFGIEVIIYGWGLSNQEEKET-INLRDSNYLGCLPVINLLQSLVMTSSQPQLWLLTNQSQWVTHQEKINPQGGSLWGLGKVIALEHPEYWGGI
IDIEMDNLASSSPILQKILLEIDRRGDEKMLAIRGKNIYCPRLRQKQKESLTNLRAIGIESSTSYLISGGLGALGIQCANWLIRQGAKNLILLSRRQPSA
TT---RKQLEAWQ----KQGVNLYLPQVDVTNYEELKTVFEYIKIN-LPPLKGIIHSAGVLADGILTTLSVDKLEMVMSPKVLGAWNLHRLSLDLPIEFF
VNFSSVASLLGSAGQGNYSAGNGYLDSFASFRH-SLNLPCLTINWGAF-DVGMAESK--QHSLTASGMELINVHEGIGLLGELINYPLSQLVMKINWEKI
GKK------------------F---------PSLFN--SPYVKDTL--------------PV------DEETLNNLFVELT-QADKEEREILLVDYLTKS
IELILNPGHINPDDNLIDLGMDSLMVMEAINNLKTDLQLMLYPREFYERPTISALASYLSQEF---------
>tr|K9YIP4|K9YIP4_CYASC Beta-ketoacyl synthase OS=Cyanobacterium stanieri (strain ATCC 29140 / PCC 7202) GN=Cyast_0285 PE=4 SV=1
----------------------QQWLYEIVWEKDTSISFPLNTPSRYLIFVDEKKQGEAWAELTSQGSQVYLVYQGESYRQE-ETTYYVNPKNKQDYQLL
LDSLDN---KIEKIIYGWAINEDDDLHN-IQLNDNNYLDCLPLIYLIQNLVNSNHHIKLWLITQNSQSITHTEKINPYGGSIWGLGKVISLEHSEYWGGM
IDIDNQGV--SLPLLTYLIN---HQEKETMTAIRNNSVFHCRLQHKTPDSYQE-PQVTVTSSGSYLITGGLGALGLETANYLISQGAKNLILVSRSQPSS
SA---SQKISQWQ----QQGINVIVKQGDVTEKESLAQIITDIRQS-LPPLKGVIHTAGVLDDGILATLSSEKIAKVMAAKVMGVNNLHQLTLDDNLDFF
ILYSSVASMVGSIGQGNYAMANSYLDSFASYRQ-SLGLPAISINWGAF-SVGMAKAT--QESLTSVGIETIPPQKGVAMIGDLINYPHSTMVVKFNWDIL
SRK------------------F---------PQLSL--SPYLKGVV--------------SSSLTEDEKDETQTQLFHQLL-KADESGRITLLIDYLIGA
IALILHIEKITPEDSLMDLGMDSLMVMEAINHLKTDLQLMLYPREIYERPQISTLAQYLAQEF---------
>tr|A0A0M8VXR8|A0A0M8VXR8_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. NRRL WC-3618 GN=ADL01_17915 PE=4 SV=1
----------------HEQSELDRWQYRIAWKPLAKVAR-PGLTGTWLVVAPAGNEAEPWRALEQSGARVLRVGPQNADRTV-------F------LEKL
RDALSDDGISVTGVL-SLPVCGPTPEPSHAVDGESVPAGALRTLALVQALGDADVTAPLWVATRGAVSVGSDATADADGAAVWGLGRVAALEHPERWGGL
VDLPETADARA---ASRLAQVLAAASGEDQVAVRGSGVFVRRLVRAPFGDVGGSAGEWSPGGGTVLVTGGTGALGAHVARWLAREGAEHLVLTSRRGPDA
PGA------AELKAELEELGTRATIAACDAADRDALARLLDGIPDD--APLTGVFHTAGVLDDGVLDGLTEGRMASVFRAKAESARHLDELTRDADLTAF
VLFSSLTGTVGAPGQGNYAAANAFLDALAERRR-AAGLPAVSLAWGPWGGGGMAAADGSEDRMRQAGLPVMDPARATESLRRATLHDSPVVVADVVWDRF
TDGFTA----------------------TRRSTLFDDLPEA--------AAARTA----HPTSAD-DTETPPLKQQLAALS----RPDAERALLDLVRTQ
AAAVLGHQAVPADGAFKGLGFDSLTSVEFRNRLGVATGLTLPVTLVFDHPSPRAVADYLAGHLL--------
>tr|A0A0M8VNS8|A0A0M8VNS8_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. AS58 GN=ADL00_11590 PE=4 SV=1
----------------HRQARPDSDDRTLPWTRHAPTAE-PPADEDLAVWPPAGAEADSWHAVGASEARISPAGPGQAAITL-------A------DLSL
RSVLAAPGAL--FTV-EWPHPPPSPEASWVTDGENDPAPAARVLRLVQEWLAERFGSRLAVVTRHAV-AAADDNVDIAGASVWGLVRSAQSEHPDRMVLI
-DVD--DDAAA---DSLLPAVIA--ADEPQLALRDGRLHAPRLTRR-----RGASARRLDTDGTVLVTGGTGGLGALFARHLVEHGIRHLLLVSRRGPDA
PGA------AELSEELAALGAEVTVAAADVGERAAVAALIASIPAS--RPLTAVVHAAGVLNDATVQSLTETQLDAVLLPKASAAGHLHELTRDLDLAAF
LLFSSVSGLTGTAGQANYAAANAYLDALAQHRA-AQGLAATSLAWGLWDGSAGMGATLTEDIVRRLGMTPLTPQQGLALFDEA---DEPL-----DPGRL
AAGN------------------------GPVPALYRGLVRT--------RPRRAA----QTGS---AGRGSGWVQQTAGLP----EAKRGDAVLALVRAT
VASVLGHTSVDPARAFKDIGFDSMAGVDLRNRLSAATGLRLPSTAVFDHPTPTALAAYLLTQVV--------
>tr|A0A0J8C1S0|A0A0J8C1S0_STRVR Polyketide synthase OS=Streptomyces viridochromogenes GN=ACM01_26010 PE=4 SV=1
-------------FALAALSPLDGALFETRWQSRPIADE-PPAPGSWLILADESGIAAELVERLGTSVPHVVARRGDEFTTEGPGHYVLDPSDPQHLARL
LDEAFA-NEPPERVVQLSALDAPAIE-DAGTAEEAARLCCLSTLHLVRTIAGRGPAPRLFVVVRGSQAAGDSQVTQPQQALAWGFGLAVAQEHPELRTTL
VDLPATDG------ADALWTQLRHADDERLVALRGTGRLVPRLTRTRPDDAG---HGATTPDGVYLITGGLGGLGRVVAERLVRRGARRLALMSRSAPTA
N---AMGWIHGLE----ERGVTVHLAHADVADRTGLTAALDAVRR-ALGPITGVVHAAGVLDDATIGNLTDERVLRVLAPKVLGTALLTELTPEA--QDF
VLFASAAGLLGSAGQSPYSAANAFLDAWAHHLA-HADRRALSLDWGAWSGVGMVAESGVRAETGRPGLVAFSAQDGGELLERVLGTARRQLPMALDWELL
ALDA----------------DAA------RSRPILADL-------V------------TAP---TGTPGTDDLVDKVF---AASTDTERAVRLEAYVRAR
VGEVSGAVQVSATTALKELGLDSLMLVRLRNAFARELGVELPAATVFSAADIRGLAQALSTALPERD-----
>tr|A0A0G3AUW2|A0A0G3AUW2_9ACTN Polyketide synthase OS=Streptomyces incarnatus GN=ABB07_37695 PE=4 SV=1
-------------FRLAALSPLDGALFETRWHPRPVAQE-PPVQGSWLILADDTGMADALGERLGSSVPHVIARTGSAFAAEGPGRYVLDPADPDHLARL
LAEAFA-GGPPERVVQLTALDAPPIG-DAGSAEQAARLCCLSTLHLVRALADRGRAPRLFVVVRGSQAAGDSSVTHPQQALAWGFGLAVAQEYPELSTTL
IDLPPTDG------ADALWTQLRHADDERLVALRGTGRLVPRLARTRPDDGG---TGETSVDGVHLITGGLGGLGRVVAERLVRRGARRLALMSRGTPDA
E---AGNWITSLQ----ERGVTVHLARADVADRESLTAALDAVRH-ACGPIATVVHAAGVLDDATVANLTDERVLRVLAPKVLGTTLLTELIPEA--RNL
VLFASAAGLLGSAGQSPYSAANAFLDAWAHHLS-RSDRRALSLDWGAWAGVGMVAGSGTRAETSRSGLVAFSPQEGGELFDRVLATARRQLPMALDWEML
TLVP----------------DAA------RTRPILGDL-------V------------TVP---SGTAASDDLVRKVF---AATTDDDRATWLEAYVRAR
VGEVSGVADVSATTALKELGLDSLMLVRLRNAFVRDLGVELPAADVFAASDIRGLARALAEGLPEQG-----
>tr|A0A0C1YD43|A0A0C1YD43_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. 150FB GN=QR77_03210 PE=4 SV=1
-------------------PAVDGWRYREAWVPLAVPDV---VPGRWLVVVPAALEREPWVS------RVVTA-MGPSAE-----VMVCHAADRASLGAE
LTAVAGAGGPLAGVLSLLASAD---------------AAPEPTLALVQAVLDAGMTASVWAVTRGAVSASGDRVPMPDQGAVWGLGRVAALEHPGVWGGL
VDLPEEADA---RVAEWLAGVVSGDTGEDQVAVRSAGAFGRRLVRAPAEGS----GGSWPTSGTALVTGGTGGLGRCVARWLVGCGTEHVVLVSRRGPDA
EGA------GAARAELEAAGARVTIAACDVADRDALARVIEGIPAD--VPLRTVIHAAGAVADVPLESLTPEGLRSDLRGKATGARHLDALTRDMTLDAF
VLFSSGAAAWGSGGQAGYAAANAVLDALAFHRR-ARGRTATSVAWGAWDGAGLLAVPGRRDKLSRLGVMPMRPELAIAALERALRDDETSVVTDTDWARF
VPA------------------FTAV----RPSPLLSGLAEAARA------------LDAGRR-ESGGSDADDAARRLADL----PARERRAVLLALVRDN
AAAVLGHTRIDADQAFRDLGFDSMTAVELRNRLVTATGLALPTTLVFDYPTATRLADHLLSHF---------
>tr|A0A0C1XER3|A0A0C1XER3_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. 150FB GN=QR77_03205 PE=4 SV=1
-------------------PAAEEWRYREEWVPLAVPDA---VPGRWLVVVPDRLEGESWVS------AVVTA-MGPRTE-----VVRCGGEDRTAFAGL
LREALGDGTPFAGVLAPAAPAD---------------EAVPFALALVQAAIDAEAAAPVWVVTRGAVAVEGD--PVRGQGGVWGLGRVAALEYPRFWGGL
VDLPEAVDA---RVAEWLAGVVSGDTGEDQVAVRDTGVFGRRLTRAPLVGP----GGSWSTSGTALITGGTGGLGAHVARWLVAHGTEHLVLVSRRGPDA
DGA------GLLRAELEAAGARVTVAACDVADRDALARVVGEIPAD--APLRTVVHAAGVNGTVGVESLTPDQLHADSRVKAVGARHLDELTGALELDAF
VLFSSGAAAWGSGGQAGYAAANAALDALAADRR-ARGRTATSVAWGAWDEVGMVVAPGHGDRLRRQGVVPMRPERAVAALERVLHDDETSVIADMDWSRF
VPT------------------FTAT----RPSRLLSALVEAERA------------TAEAP--LTGEEGESDFERHAAGL----SGRQRTLFLVELVRDH
AAVVLGHQEIAPDQAFRDIGFDSLTAVELRDRIAEATGLKLPTTTVFDHPTAGRLAEHLDALL---------
>tr|L0DP05|L0DP05_SINAD Amino acid adenylation enzyme/thioester reductase family protein OS=Singulisphaera acidiphila (strain ATCC BAA-1392 / DSM 18658 / VKM B-2454 / MOB10) GN=Sinac_7054 PE=4 SV=1
-------------------PSIAEWLYELDWIAKEPTARPDSSEGPWLILEDSRGVGQALRAHLERGIPCELV-----------------PCVDVDLEGL
LKT-----KAYHGIVHLGSLDTEVSAPSLAALDDAERKGVGSVLPLIQALGNLKPKPKLWLVTRGAQPTTSPGVQGLAQTPLWGMGRSIALEYAECWGGL
IDLDPEAVD---GGAAALAAELLDGDGEDQVALRSQGRYVPRLVRRKAPAPH-HGAPLVRPEGTYLITGGLGELGLQAARWLAERGARRLVLVSRRPLPL
RTQWERKGVAAIQD-LERLGATVVVANADVADPEAMAALFERLQA-TLPPIVGILHTAGFITNESTRDLDRQTLAAVLRPKVAGTLVLDALSRDLPLDFF
GLFSSVASILGA-KEAHYAAANAFLDAFAHVSK-AQGRPVLSVNWGPWAGAGMAASPDRMRAFHLLGFKPLEPDRAFRVLEGLIHEGRAQLVADVDWSGL
KRLHAE-EG-----N----------------RHLLEKIEET-------RRPQR-------DLRPSG---RRELADWR-----NAPLEQRRETLVRYFRDR
VAGVLRLDRIDPARPLNTLGLDSLMAIELKGGVEADLGTILPLTSLMTGPTITELADQAIA-----------
>tr|A0A0F5A2A6|A0A0F5A2A6_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. MUSC164 GN=VT50_36465 PE=4 SV=1
------------------QSTIDGWRYRVSWKPLTDVAD-GPLSGTWLVVVPASRAGDELVGLEGHGAHVVRVAVDER--D-------LD---ADVLAER
LREVAAETPELGGVLSLLALDEEPCPG-----HPALSGGYALTLVLVRAMVRADIPAPLWCGTRGAVSVGRDRLTSPTQAMVWALGRVAGLELPPLWGGL
VDLPQSLDE---RGAARLAGVLSAEGGEDQVAVRGSGVFVRRLVRSAPAVG---EETPWRARGTVLVTGGTGGLGGQVARWLVRSGAEHLVLTSRRGLEA
AG------AAELKAELEDMGAEVTVAACDAADRDALAAVLAAVPE--HQPLTGVVHAAGITIAASLLETGLADAARVVSGKVAGAVNLDELLGDRELDAF
VVFSSISGVWGGGSQGVYGSGNAFLDALVEQRR-ARGLAGTAVSWGPWAEGGMATRDDAGEQLARRGLPAMAPQLAIAALERAVAGDDGVVVVDVDWERF
APSFTAV------------------R----PSPLLGDLEEALETKGEG--------------DESADAAGAQLRERLKPL----TEGERDRALLDLVRKH
AASVLGYELVEPNRAFRDLGFDSLTAVDLRNRLAAETGLTLPATLVFDYPSAATLAAQLRTEVL--------
>tr|A0A0M8VPX2|A0A0M8VPX2_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. MMG1121 GN=ADK64_03130 PE=4 SV=1
------------------RSTVNSWRYKVTWRPLSTPPAIGRLAGTWLLAVPAPLVAEAAEALTRSGAQVVPVEVDCA---------TVE---RAALAQT
LAAASPEPSPIAGVLSLLGLDEAPHPDH-----PVVPQGVAATLALVQALGGSAIDAPLWLATRGAVSVAGTDLTSPAQAQVWGLGRVVGLEHPERWGGI
VDLPMELGES---TGQRLAEVLGGTGGEDQLAVRRSGTYIRRLVEAPQTAKPRANPTAWQPRGTVLVTGGTGALGSQVARWLAKSGAEHLLLVGRRGAEA
PGA------EALRAELHALGTEVTIAACDVADREALARLLAE------HPPTAVVHAAGVGQLTPITDTTLDGYAEVLGAKVGGAVNLDELLAPDQLEAL
VFFSSNAGVWGSGGQGAYGAANAFLDALAQHRR-ARGGHATSVAWGSWGGAGMAVEEGADAHLRARGLRPMDPDLAIAALAGALDQDETTVVADVDWARF
VP------------------LFTSARS----RPLIAEL------------PAVRALLEE-PEEPSGSG-DAALRQQLAALSA----TGQADLLLALVREQ
AAAVLGHSTVAAGRAFRELGFDSLTAVQLRNRLSARTGLRLPTALIFDYPNATALAGHLRDQI---------
>tr|B4WHZ1|B4WHZ1_9SYNE KR domain family OS=Synechococcus sp. PCC 7335 GN=S7335_3862 PE=4 SV=1
-------------------PHWKDWIYTVEWQPTAVVDSPLAAGDHWLILGEDAARLKAIARLLEQAQNCTLALLGKAQQQSE-AYLEIDREHPESFHTQ
VQR----ASSWRGVLYFSGSD--------------VEQSCKGALYITQALVSCNLSTRLLFVTDRAQAVLGDDSLNVAQSPLWGLGRTVALEHPELNCVC
LDLDSTASEQQ--VLSSLLAEIYQDSRESQVAYRNGKRYVARLTRPIQPAPASSKPIAIRANATYLITGGAGALGLQVAQWLVDQGARSLILVSMKPQF-
--KKIQQHIDRLR----QSGVDVKMLHTNLLDRERLQRLVHTLQS-TSAPLKGLFHLAGEIDDGVLQQQSWITFECVLSAKVTGTWNLHQVTQDMSLDYF
VMFSSVASLLGSVGQANYAAANSFLDAIAHFRR-QQGLPGLSINWAAWAGSGLADTPEVEQRLKRAGIPLIEPETALEILDWLLSSTEAQILPGQNWQMA
HVQTSL------------LTAIES------TALKSRK----SKRSLEHSSQ--PTQQSPRPSSQ--ESSKSHVRSTIQ----ADLKVGNTTALIQHLQDQ
LAIVLGQAAVDQSADFTDLGLDSLTAVEFRNRLQTSLKCSLPATLVYDYPTLAQLTDYIASLL---------
>tr|Q66VY5|Q66VY5_STRRM Rimocidin synthase (Fragment) OS=Streptomyces rimosus GN=rms PE=4 SV=2
------------------ALDVDGWRYQVTWKPLTGTSA-STLSGPWLALVPAGGADDEWTAALGDDAVSV----------------EADPADSRALTAR
LAELAAQGQEFAGVVSLLAARTGEG---------VASGGAAWPDAAVQALADAGIGARLWYVTRGAVAVGRETDVDAAQAAVWGAGRVAALDHPDLWGGL
VDIADVLDRRS---ADRFRAVLSGTGGEDQVALRSSGAFGRRLVRATADTP----STPWQPSGTVLVVGGASGTGGLCARWLAGQGAQHILLAGPATPE-
--------ADTLPAELDGLGAELTRVTCDPADSDALLNALTAL------PPTAPLTAVVYADAEALSGDGEPGLAALHTAVENLAAVAEAAAGERPLDAF
VLCSSIAGTWGAGGRGAEAAAGALLDALARRYR-ARGLRALSVAWGAWADTT---DDSLAAHLRVNGLPVMDAERALSALSRSAGTDAAVTVADVRWDRF
APA------------------FTRNRR----GALFTDLPE--------ARAAL------AEPGNAGQGTATGLGARLAGR----PAAEQTEALLTLIRGE
VATVLGFDAVPSGPAFKDLGFDSLTAVDLRNQLATATGLSLPATLVFDYPTAEALAGHLRTELF--------
>tr|A0ACI1|A0ACI1_STRAM Putative modular polyketide synthase OS=Streptomyces ambofaciens ATCC 23877 GN=SAM23877_7117 PE=4 SV=2
------------------HSTVNSWRYREAWQPLDIPRA-GTLDGRWLLLHTEGVDTGHAEALLEAEPV-D----------------VTVPDDSWGLSEL
LRE-AAGAEPVTGILSLLADDREDG---------AVSVGLGATLTVVQALADAEVTAPLWCVTTGTVATHRDRIVDPAAARLWGLGRVAALEHPERWGGL
IDLPIDPEPRA---TARLAA--VLAGTEDQVAVRAEGVYTRRLLHAPAAEL----LPGKVAPEAVLITGGTGALGAETARMLARRGTRKLVLSGPGAPG-
--------AAELVAELADLGATAVAHACDAADREGLAALLAEH-------VTGVVHAAGTDPALPLDSTSVPVLAEGLRAKAVGAEHLDALLP-D-AELF
VVFSSIAGVWGSGGQAAYAAANAHLDALVAARR-AAGRSGTAVAWGSWAQIGMAARDGVDEYLKRRGLRPMPPGLCVAALEHAIDTGDTVVVADVDWARF
APA------------------FTSRRP----SPLLSALPE--------ATEAL------AG-GPAAEDQASAVRTLLAGL----PESEWARTVLDLVRRE
TAAVLGYEPVDADRPFKDLGVDSLTAVTVRNRVAGALDLRLPTTLVFDHPTPSDVSRHVLSLVS--------
>tr|A0A0B5ESF4|A0A0B5ESF4_9ACTN SalB OS=Streptomyces albus GN=SLNWT_0686 PE=4 SV=1
------------------RVRLNSLCYEVSWQVLTGAPA-GTRSGQWAVLAPGGGTGGEAARLVALSAQVI----------------ETAPDE----HER
LAPALREHGPLDGVLSLLALDPAAT---------T--------VALVSAANEAGSCGRLWTLTRGAVAVSSESPDSLAQSAAWGLGRVAALEHPDLWGGL
IDLPASVDALA---ASRIVKVTHPTPGEDQLAVRANGLFGRRLVAAPLPAA----AERWEPRGTVLITGGSGALAGHLARWAVERGARDLLLVGAEAPG-
--------ASALREELTGSGAQVTFAAVDVSVREDLAALLAEH-------VDAVFHTAGVLDDGTLLSTGAERLARVRAPKAEAALLLDELTRAQDLSAF
VLFSSLAGTLGSPGQSAYAAANATLDALAERRR-AEGLPGTSIAWGPWAGGGMAAEAGDRR-RGQGAVTALDPETALSTLGAVLDHGRTQFVAEVDWDRF
VPA------------------FTAVRP----SALLAALAP--------PTGST------EPATAQGAPDPTGLRGRLAGL----SVEGQLREVLELVRSR
AAGVLGFGEVGAERSFRDLGVDSLIAVELRNVLASVCGVSLPATVVFDYPTPLALAGFLRDEVC--------
>tr|A0A0F7W4D3|A0A0F7W4D3_9ACTN Chaxalactin biosynthesis PKS homolog to Erythronolide synthase, modules 1 and 2 OS=Streptomyces leeuwenhoekii GN=sle_61430 PE=4
------------------VPAVDGWCYRVAEEPVLTGAP-AVLSGRWVLVLPAGYEDDPWTGAL------------------------------AG-AEV
ERSTAGLAGPVSGVLSALALAEGAP---------AVPTGLAATLDLLHDLASSDSGARLWCLTRTAGGA--------EQAMVAGLGRVAALELPRVWGGL
IELPAEPGTGT---DGLVRA--LAQDTEDQIAVRADGPRARRLVPVPRTAA----PQPWKPRGTVLVTGGTGGLGAHLARHLARPGVD-LVLLGPEAPG-
--------AEELRAELLSAGASVTVAACDVTDRQALAELLAGL------PPSAVVHTAGTSRSQPLAETGPAELAEVFAAKVLGAHHLDELLD-GPLDAF
VLFSSIAGVWGSGGQAAYAAANAYLDALAERRR-ARGLPATAVAWGPWAGDGMVD-DSTAEYLRGRGLRVLPPEAALTALERAVAEDHTLVVVDVDWGRF
LPA------------------YTSARR----APLFDRLTA--------TRPHR------AG-TARTTARNQAAQTEWAGL----SEAALPAAVLGLVRGQ
AAAVLGLEEVDTGRAFTAAGFDSLMSIDLRDRLAAATGLRLPATLVFDHPDPEALTRHLCAELA--------
>tr|M3BK51|M3BK51_9ACTN Acyl transferase (Fragment) OS=Streptomyces gancidicus BKS 13-15 GN=H114_28566 PE=4 SV=1
-----------------ARSTLDRWRYRVTWRPCAEPPAHDVLRDTWLIVVPAGHEDDPLVRAVGAEARVLVA-GEAEA-------------ERDRMADL
LRQHS-EDTVVGGVLSLLALDESPWS-----PEGVLPTGMVLMTALLQALGDAQVEAPMWCATRGAVTVRRDPLLSPLQAMSWGLGRIAALEYPQRWGGL
LDLPEQFDA---RAARRLAAALSGTLEEDHLAVRPSGIFARRLVRAGEGP---RPGGVWKPSGTVLVTGGTGGIGGHIARWLARGGAEHLVLVSRRGPEA
PG--ADDLVAEL----AELGTPASVVACDVSDAQAVRRLVDDLP--GGGTLTAVFHTAGIIDDGLIDALTPQRAHDVLRPKADAALALDAATRHLDLNAF
VLFSSMAGTLGGPGQGSYAAANAHLDALAARRR-AEGLPATSVGWGTWAGGGMVGEE-VAERLRRDGVPPMDPELAVASLQKALDEDEEFVVADVDWKLI
TVR------------------------------AFAALRELPE----PRTAVTAVT-DRTEQKETDAVDGPPLVKRLAAL----PPAERRAALLMEVRDE
AAAVLGHDAVPEGRAFRDLGFDSLTAVELRNRFAEATGLRLPVTLAFDHPTASALAAHLDAEL---------
>tr|A0A0Q8Z0J1|A0A0Q8Z0J1_9ACTN Polyketide synthase OS=Streptomyces sp. Root264 GN=ASE41_05755 PE=4 SV=1
-----------------NHSTLDGWRYRVAWRPRTEQPARHELANTWLLVVPAGYEDDPLVRAISAGARVLVV-GGPDA-------------ERDRMADL
VRALA-DGVEVGGVLSLLALDESPWS-----AEGVLPTGLVLTTTLLQVLGDTRLEAPVWCATRGAVAVRRDRLTSPLQAMTWGLGRIAALEYPQRWGGL
VDLPGTLDD---RAARRLIGALSGTLEEDHLAVRASGLFARRLVRAGDGP---RPEGSWRPSGTVLVTGGTGGLGRHVARWLARGGAEHLVLASRRGPDA
SG--AAELVAEL----AESGTQATVVACDVSDAEAVRRLVDDLP--GGGTLTAVVHTAGIIDDGLIDALTPQRAHDVLRPKADAALALDAATRHLDLDAF
VLFSSMAGTLGGPGQGSYAAANAFLDALAAARR-AQGLPATSIGWGTWAGGGMVGEE-VAERLRRDGVPPMDPELAIASLQKALEQDEEFIVADVDWKLI
TAR------------------------------AFAALRELPE----ARVPLST----DSGEKKADSVDGPPLVQRLAGL----SPAERRAALVTEVRAQ
ASAVLGHDAVPDGSAFRDVGFDSLTAVELRNRFVEATGLRLPVTLAFDHPSAGALAAYLDAEL---------
>tr|A0A0F2T5L0|A0A0F2T5L0_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces rubellomurinus GN=VM95_33085 PE=4 SV=1
--------------------APQDPLYAVRWTALPHPAQP-AAPGAWAVLGD-GGLA-----------------PVPD------------ATRHSDLAAL
ARALDDGLPAPAVVVLPWPTAETPGLPA----PEAVHAAVARALDTVQTWLADPAATRLAVVTRGAVSVGDDDVRDLAAAAVGGLVRSAMSENPDRIV-L
VDLDDDPASVP--ALAAAT-ATAADTGEPQLAVRAGTLYAPRIARSTPGDAA---RPAFDPDGTVLVTGGTGALGALAARHLVTAHGVRRLLLTSRGPAA
--PGAAELAAEL----TALGATVELAACDVADRAALAALLAAVPA--AHPLRAVVHTAGAVDDGVIAALTPERCGPVLRPKVDAAVHLHELTHGLDLTAF
VLYSSVAGVIGSRGQANYAAGNAFLDALAQHRR-AAGLPGVSLAWGLWEESGLMREDTDRHRIDRSGVLPLSAAQGLALFDAALGRPEALLAVRLDLTAL
RR--------------------------------FDELPVILS----ALVPARR---------RAGGEEARRLAQRLAGR----PEAEQVQLLTDLTRRQ
AAVVLGHETVGADRAFTELGFDSLTALEMRNRLNTATGLRLPATVLFDHPSATALARYLRTEL---------
>tr|D9WB22|D9WB22_9ACTN Modular polyketide synthase OS=Streptomyces himastatinicus ATCC 53653 GN=SSOG_00528 PE=4 SV=1
--------------------VGRDSLFRVEWAPVAEGTDA-G-PSVVAVVGD-GGLS-----------------GGLR------------DVGCADLAAL
A---VAEAPMPDV-VLAEVATERPGDGV----VDSAHATVAQTLGLVQRWLEGEAGSRLVVVTRGAV-------GDLAVASVRGLLRSAQSEHPDRIT-L
LDLGDGAVSGA--VLS-----RALAQSEPELAVREGRLAVPRLARVGVPDAV---ARVWDGPGSVLVTGGTGGLGAVVARHLVAERGVRDLLLVSRGMAS
--PGAEDLVAEL----VESGARVEVVACDVADRDALAGVLA------GREVSAVVHAAGVLDDGLMGALTPGRVDAVLRPKVDAAWHLHELTRDLDLSAF
VVFSSAAGTFGSAGQGSYAAGNAFLDALVEYRR-GLGLPGVSLAWGPWDQDGMV-GEADRERMHRSGFPPLSVEQGVALFDAAVGAGEPVVLVRLDLSAL
RA--------------------------------RGEVSPLLR----GLIRTPF---------R--RAAVTGLAQRLSGL----GEVEQGEVLLDLVRSQ
VAMVLGHAAIDPGRSFRDLGFDSLMAVELRNGLGAATGLRLPATLVFDYPTAQALVEHLFDEL---------
>tr|H1KFY5|H1KFY5_METEX Mycocerosate synthase, 6-deoxyerythronolide-B synthase OS=Methylobacterium extorquens DSM 13060 GN=MetexDRAFT_1547 PE=4 SV=1
--------------------ERSINIFEPVWLPDAA-----VGFGALLALGQDLGLT-----------------GGTT------------QERKDHLEHL
WRTFKADGSLPAAVVADLR--HQ---------PAVSPHGLERHLGLMALLKSVAKSCRMILICQG-----------PAASAAAAMMRSVHIEAPSLDFTV
LETDGAEHPAYLF-VDAEA-KRTAGGGVRHVRFIGGTPLVRRYAALDLPSRD---ADVR-SGDVVLITGGLGAVGLHIAKHLALHRGVRIALLGRS-RPA
--EHSRAAVASL----RMAEGDCSYWECDCSSGEDLTQTLADIRSR-MGPLTGILHCAGVLKDAFFTRHTDTERYEVLKSKALSARLLDEMTRQDPLRWF
VLSSALAAVCGNIGQSVYGLSNGWLDGFAEERN-SLTAATVAVAWPLWNTTGMQASERFLRRLQDEGLDLLEPDEGARLFAAATWSDRSLIVIKGDEERS
SR--------------------------------ILGIK---D----AGI-------------PAGNTDDATLEPQGTAD----ANGGQEDRVLRYLIGT
LSDV-TGERIEPDTPLEAFGLDSLLVLEMSDRLQERF-PRIARTALFEARTLRALARLLIDEL---------
>tr|F5RC13|F5RC13_METUF Putative beta-ketoacyl synthase OS=Methyloversatilis universalis (strain ATCC BAA-1314 / JCM 13912 / FAM5) GN=METUNv1_01653 PE=
----------------------PLHLLQRSWSACDRPRSV-VLPV-MLAAGGVRRLH-----------------PGQT------------LADPAHRRAL
LELLQQRDAFPDTVVWLAG--SA---------CETVDADVRRFVSL-QLLVGAGRALRLVYVGTPSA-----DDARCFHAAMSGLLKSLHLEAPRVSAVL
LELDAASHDDPVAIAAALV-HPASPGHAPRLRVRDGRLEEARFGWLEAPATG---WQPT-RGATYLITGGMGALGRTFARWLA-RCGVHVALLGRS-PLD
--EEGARVVAAL----GGEGASVVYVQGDVTDTASLAGALQQVRAT-LGPVRGVIHAAGVLRDAFFVKHGDDDWQAVLAPKITAARLLDQATREDPLEAF
VLFSSLAGAHGNVGQSVYAYANAWLDDYAELRA-QAVAETLALAWPLWRSDGMQAPPPVMQWMAERGLELLDAEQGIQALRAAMATTVAGVVCSGRREGV
AR--------------------------------LMSVD---D----GAS-------------CDTAAAASSVPVA--------PAGDIVPALCSRLGDM
LARA-CGSRVVPATPLQSLGLDSIMVMDLNGELDQHF-SSLSKTLLYEADTVQDLASRIAAVE---------
>tr|S4XU45|S4XU45_SORCE Uncharacterized protein OS=Sorangium cellulosum So0157-2 GN=SCE1572_13250 PE=3 SV=1
-------------------------LYQVAWREAAPAPDVKTPSGAWLLLAEGSALGDAVARLRSAGAQCTTLALHQDAALRGGELRATASRVGEALGRA
VAAAAARPQPLEGVVCLWGTSAATE--AGRSPADAAEALAAAGLAVAQALARQKVPSRLWWVTEGAQAVRRGEQVAAQLAPLWGLGRVVMQEHPDLGCTL
LDLEPG----AEDAVEALWSEITRADEENQVAWRSGKRLAARLVEAPAAAALVAPAPAIPGSSTVLITGGLGALGLHVARWLEEHHVQHLVLAGRRAP--
-EGDRLAVVEALRA----AGTRVTVAQADVADAAQVKALLDAIPEEL--PLRGVIHAAGVLDDGVLSQQDAERFAAALAPKVRGAWNLHEQTRHVPLAFF
VLFSSAASLLGPSGQSSYAAANAFLDMLAHARR-AEGLPAHSLNWGPWSGTGMAAEMDKQARLARRGIRGLAPEQALALLGQALARPEPELC--------
--------------------------------ALLLDVLALRQELSSGPVPPLWRALVAPHGGRAQARAAGGWAEQLGAL----APAARAAEVEAAVRAE
VAKVLSLADVRTGRPFKELGLDSLMAVELRNALAARLRVRLPATLAFDHPTVEAMTRYLLDLLSPDRESAKP
>tr|A0A0L8MWJ6|A0A0L8MWJ6_9ACTN Polyketide synthase OS=Streptomyces griseoflavus GN=ADK76_22730 PE=4 SV=1
-----------------------SLVSRVRWRPAPGPER-EPAQGTWMILHHGDGIGELTGRQLREGARVVEVRLGDSGEHQGGDRLVMAHADEDGFRRL
WEAV---GEPVTGVLHLWNATEATGDG---AEESELRTGLHGCFAALKTLGERQRASRFLVVTRHAQPVVDGDTPVPARAALWGLVRTAAIEYPGLRPRL
VDLDDAV--------EALAAEL--DDGPTEVGYRNGVRHEPVRVSEQWSRP---ARRSIRPGGRYLVLGGHGGLGLEVARRFAAEGAGLVALVSRRGAAG
ADP---SRLTGA----GSAACTVVSYAADVTVPGQLRDVVARIRGE-HGELHGVVHAAGTLKDGLIRSTTVEDVTAVMRPKADGVRELAAAVDGTDLDFA
VLFASVSGAFGNLGQGGYAAANAYLDAFAHR----RGAPWLSVDWGLWGEVGMGTAV--ADQLRRRGVRPLGTAEALDALTGVLGGDARQVVIAHDGAEP
-----HPD------G----------------TGPRPDAGD--R-HATEATPTRA------RPESDG--P------------DGVHAEAGRERVEDELERF
LAERLGVTPFDRRVPLAEYGMSSIMSVELSEELSRRWDLHLPATLFLEHGDFADLAQALTDRYG--------
>tr|V6KLY5|V6KLY5_STRNV Uncharacterized protein OS=Streptomyces niveus NCIMB 11891 GN=M877_03055 PE=4 SV=1
-----------------------LPITRIDWRPAPAGDT-DPATGTWVVLHNGGTLGERAARQLRDGARVVEVGVGPAGT-HGPDHRTLTRPDEETFRRL
WEEI---GDPVAGVLHLWNADAAPDDP---GEETELRLGLYGCLAALRTLGERQRKSRFHVVTRDGQPVGTGDRPVPARAALWGFVRTAAIEYPGLRPRL
IDIDQPS--------DTLRAVA--ADGPTEVGYRRGVRHVPVRVRDRSAYTAPGAKGPIRQGGRYLVLGGHGGLGLEVADRFAREGAGVVALVSRSGAAP
ADD---DRTGAI----SARGCEVVSYGADVTSPGALAAVVERFRAE-FGELHGVVHAAGTLKDGLIRSATAEDIAAVMRPKADGVRELAAAVAGRDLDFA
VLFASVSGTFGNLGQGGYAAANAYLDGFAQA----HGEPWLSVDWGLWGEVGMGTAV--AEQLRRRGVRPLGTTEGLDALIAVLGADLRQVIVAHDAGDV
-----IEE------P----------------GAPFG---V--H--------TKA------PDDVSV--D------------VGPTGEGDGERVGEALEQF
LTERLGVTSFDRETPLSDYGMSSIMSVELSEELSSRWGVHLPATLFLEYGEFDELVEALTGRYG--------
>tr|G0Q416|G0Q416_STRGR Amino acid adenylation domain protein OS=Streptomyces griseus XylebKG-1 GN=SACT1_0942 PE=4 SV=1
-----------------ARTTIDSWLAEPVWTDCPPLPAGAARDHDWLVLADDGGTADAFAALAARGERCRLVRRGAAYTASDGAAFTVDPASDADLRRL
LADLDRDGGPFRAVLHLWNLDAPALATDRASLTDHTGAGAYSLIALARLLSARGTGGRLHIVTRGAQPALPGEGPEPLGAPAWGIGRVLRQELTEHPGKL
IDLDPRRQPGDRAEAAALLGEVLS-DDEEEIALRDGGRRTSRLRPARELTR--PLPPRLRADGSYLVTGAFGALGRLLCRTLVRRGARRIILVGRTPVPA
REKWAGRAVALLR-ELEALGAQPVLATLDITDEDALTGWLDAHRRSGAPPVRGVFHLAGQVRDTLVADLDRAAFDAVHDPKTVGAHLLHRHLRDEPLEHF
VLFASIASLLTTAGQTNYAAGNAFLDALAHHRR-ARHLPALSLDWGPWA-TGMIEELGLDHYLHSRGMSSLSPEAGMAVLERVLGQDHAQLVVVVDWPVF
LA------------------WYPSS------PPLVAELAAA----A--APPA-----D--AASGNGFLDT---------FR-AADEETRRTLVGDRFAAL
SATVLGTDRIDPATGLGELGLDSLLAMELRARIHAELGVALPVVALLSGTPAGELAAQLHD-----------
>tr|A0A014KX73|A0A014KX73_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. PRh5 GN=Z951_46245 PE=4 SV=1
-------------------SVINSWRYQTTWKRLPTPPTRPDLSGTWLLIIPAGAVATAAQALTGHGATLRHVL----------DTRTVH---RDALADH
LTRLAT-EGEPVGVLSLLALDEEPHPS-----YAAVPSGLAATAVLVQALGDAEIPAPLWCLTQGAVAASGDPLPSPRQAQTWGLGRAAALEHPRRWGGL
IDLPTVIDH---HTADRLAALLAPGGPEDQTAIRATGSYARRLRRAGTPTT---APRTWQPTGTTLITGGTGGLGAHVARWLARHGAPHLHLISRSGPDA
PGA--TQLAQEL----TDLGTTVTITACDASDRTALQHLLDTIPAE--HPLTTVIHAAGTSDTELIADLEPERLQHVLGPKALAAAHLHELTQGLDLSAF
VLFSSGAAAWGGSRQGAYAAANTYLDALAEHRR-ARGLPATSLAWGPWGDAGMAADETALAFYGRRGLSPLSPELAVASLQHALDHRDTTTVADIDWEKF
PTAFTAQR------------------P----SPLLDELVTAA------ENPT--------GRTAGTSTDTTSLQQRLSA----ATPEQQHQFLLERIQSL
AASILGHDAIPPGQPFQELGFDSLTAVELRNQLATATGTDLAPTLVFDHPTPNALATYLRAEL---------
>tr|A0A086K178|A0A086K178_TOXGO Putative type I fatty acid synthase OS=Toxoplasma gondii GAB2-2007-GAL-DOM2 GN=TGDOM2_204560B PE=4 SV=1
---------------------ESNKLWSVEWRASHQQPVPVDHSTNWLIAGVHPAVQSQLEEFFLPGAKVVFCAPS--------------V-VATDVRRL
LQ-----QEAWNGIIHIGGVTASISE----------MECLSDVLVLLQAVIDWPRLPAMFLVTRGACCEATEHSLAPVHSGMRGLFRTAKAELEALWNRY
INIEPSSDKQTVEELRQVFSEPSKPFYESESLLRDGELLLPRLVPASLEDCGDGNALAEAMTGTIVITGGLGGIGLVLAKWLTGQEARAVVLVSRTGTPS
AEVQRSEDWHLLQSR-RQHQTRIVTASCDVGDREQVKLLFRSLRAVELPPIRGIFHAAGVLRDCPIQKQDAETLASVFRPKSQGAWNIHNALEEEGLKVF
LMFSSIASLVGNPGQANYAAANSSLDALASYRR-CRGLAGHSIQWGPWIEQGMAAEL--GERLERAGFRGISNKVGVEVTEAVVSQGTDFVVAEFIWPRF
VMRYRG------------------C-----LPAIFEEQTRSVTVRMRDERSSRQ--------AAGPEMHQES---AF----ASMAPDELRALIQATVSGA
AKQVLGTEEPPADAPLQALGIDSLGAVEFRNAVQDAFDIRLSATLLFDYPSVQAVSDHLWSMVR--------
>tr|U6GPI9|U6GPI9_EIMAC Type I fatty acid synthase, putative (Fragment) OS=Eimeria acervulina GN=EAH_00065030 PE=4 SV=1
---------------------ARGLLWKVKWVEGKTGHMKQGRALQWLAYGVETETACSMQRVDIRGERCNGCDA-----------------------DG
VK-----LDEWDAVLHFGGACQCWDGA---------VDYTADVLALLQGIANHTEIPPIVIVVAGAFAVRPGQAAHPLLAGVRGLCRTARLEMEATANRL
IDLESTGQQAAHEMIHQVASTAGGRYVMTEVAVRGGRMFTPQLTFSDIRLLRAGDR--VGQGETCIITGGLGGLGLVVALWLAGNGAKTVILLSRTGTPP
REGTTAELWQQLTEK-C-RRTEVIVQQCDVARVSDIEELFARIESHFVKPLTGIFHSAGVLVDKPLLQQDRRSVELVFNPKVEGAWNLHKCLGAEQLKYF
VMFSSSVGLLGNAGQANYAAANCCIDELALYRR-SRGLTAHSIQWGPWVEQGMAAQL--QGRFAKAGFGGISNALGLLTLNATLQQN-ETVVGPVYWGRF
FPRYRF------------------A-----TPKVFEEIGMLETTASKTAATSSY--------RSGPRVEATQ---QA----NAGKQKDKRKHIQQVVMQA
AKSVLNVSGVTLEAPLQELGIDSLGAIEFRDAIQAALNVRLSATVLFDHPTVDALTKFLLQEIS--------
>tr|A0A0G4EHS9|A0A0G4EHS9_9ALVE Uncharacterized protein OS=Vitrella brassicaformis CCMP3155 GN=Vbra_7413 PE=4 SV=1
---------------------PRDILWEVTWKQAEPSKEAAAAEPRWLLFGVPAAWKKVLSRLVERESRLIAYGET--------------P-DAMDEKIL
AD-----KNKWDCVLHMGSLEKRSDP----------VVVVSEALRMAQVILK-NVLPAIWLVTRGTQLALPDLPEIPRHAGLWGFAKTARLELENNIGTC
VDIDPTSPDTVD--IEQMAIELGKRWSKEEVLARSGKIKPPLHTFDVIIQIDEATPAGRQTDGCYVITGGLGGLGLLVADWLVEEGAKNVALLSRRGKPT
DAVAASDLWTKLTAP-EPHGRSKATIYCNVSKKDECENLFADLKKLPKNPVRGVFHAAERLDDAALNNQTKDKVEKVYLPKVMGAWNIHELS--IPLDHF
MMFSSVASLLGNFGQTNYSAANSCLDALALYRK-SQGLPCQSIQWGPWIEQGMAAEL--KQHLDKVGIRGITNELGLRVMGDVMRQGMPSVVGGLKWAIF
LRRYG-------------------D-----MPAFFSEIPMAASAESGG-----------------GKVDLK-----------AI----SKLDLSGLLSSL
AQQVSGSEKPPIDAPLMDLGLDSLGAVEFRNSIAEVTGVRVPQTLVFENPTIEVIADFILDTAH--------
>tr|A0A0B5FB63|A0A0B5FB63_9ACTN Acyl transferase OS=Streptomyces albus GN=SLNWT_7326 PE=4 SV=1
-------------------AAQDSWRYRIGWQPVAGADS-PALSGTWLLAVPDAPLVEEVAGWSGAGATVVTVPVGDEERG-------------ALAARL
TEAL--GGGAPGGVLSLLALNEAPHPAHP-----EVPAAVAATLALVQALTAAGIEAPLWCLTRGAVSTGGAHLAAPGQALLWGLGAVVALEHPQRWGGL
VDLPAQRDAY---AGELLVAAL-GQDGEDQLAVRPSGLLARRLRRAGADA----ATEGWRPRGTVLVTGGTGGVGAQIARWLARNGAAHLVLAGRRGPEA
PGA------EALEAELAELGAQVTIAACDVADREALEALFDSLAEDGGSALTAVVHAAGALEDATVDALTVEQTARVLLPKVAGARNLDDLTRERGLDAF
VVLSSIAGTLGAAGQANYAAANAFVDALARRRR-GDGLPGVSIAWSAWADGGMLGAD-VAEQLRRRGVRLLDGEQATGILGRSVSAGDGLVVADLDWERF
APSLSATR------P----------------LPLLAEI--------APGDPAQASGAE------AEEAGGGALRARLAAL----DPADQDSALAQLVAEQ
AAAALGYAAIEAGRAFKELGFDSLTAVDLRNRLGAATGLRLPVTLVFDYPTADDLAQLLREEL---------
>tr|A0A014NVA9|A0A014NVA9_9ACTN Polyketide synthase OS=Streptomyces sp. PRh5 GN=Z951_39950 PE=4 SV=1
------------------QNTVDGWRYQAVWKPLASASE-TTLSGTWLVFSEGRGVATVLDGLAGRGAHVVRVAVGAADDR-----EVIT-------ERL
RVALDGAAVEPSGVFSLLGLDESAHE-----SFEVVPAGLAATVGLVQALGDADVVAPLWCGTRGAVSVGRDRLVSPVQSMLWGLGRILEAEYPQRWGGV
VDLPETMDD---RAMTRLAGVLTAAESEDQVAVRGSGVFAKRLVRASAPEAT--AADGWRPSGSVLVTGGTGALGGHVARWLARTGAEHLVLTSRRGMEA
E------GAAELKAELEALGARVTVPACDAADRAALAAVLDAIPQE-F-PLTAVVHAAGVLDDGVVDALTARRAAGVLRPKVDAARNLHELTAGMDLSAF
VLFSSAAATLGGPGQGSYAAGNAYLDALALQRR-ADGLPATSIAWGAWAGGGLATGE-VGERMSRSGILAMPPELAIAALQQALDHDETFLVADIDWTRF
EADSV-------------------------DTPLFRQLRSARSTTT-G---K------Q--LTESAAPGRGELHDRLAALP----AEKREGALRDLVRAQ
AADVLAHDAVASDRAFRDLGFDSLTAVELRNRIGAATGLRLPVSLVFDYPTPTVLARFLNGEM---------
>tr|B5X0I1|B5X0I1_STIAD Nonribosomal peptide synthetase/ polyketide synthase OS=Stigmatella aurantiaca (strain DW4/3-1) GN=dkxG PE=4 SV=1
-------------------ASLDELLYERRWEPLALEGAGAGDNRPCLILADRAGFGRQLAEELTRGRTCFLAFRGQAFRRLDETSVEV-PGEPAALAEA
LRTLD-LPASVSDAILLWGLDGPDAEMDVESLGQATLLGGGGALGLLQYLMGRGYSDAVWLITRGAQPVKPGPLPGMAQSVIWGMARPVAIESSELDCRC
VDLDPRGEQ--LAQVGLLAQEIRRRVADNQVAYRQG-RYVARLRRVEARKLLVERVQRFRPDRSYLVAGGLGRLGLLTAELLANRGARNIVLTGRDSVSP
Q---AAERLERL----REQGVRVEYRQADIADLGQLSALLREVGR-EMAPLGGVFHSAGVLDDGVLRQQSWSRFETVLRPKARGSWNLHVLTADMPLEHF
VLFSSVASLVGSAGQANHCAATAFQDALAHHRR-ALGLPGLSINWGVWAGDAG-ARVNVSEQARTPGFGVIAKQQGLQALEMLLAAQVAQAVAVIDWAAF
GAGRP----------S----PYD------------AD----LREKAGGR-------------T----AGRETFLAKLT----SAPIAHRRKMLMDYLREQ
VAWMRGMESIDPAQGFSEMGIDSLAALQLKNRLQGGLGVSLPATLVFNYPTTEKLAEQLMA-----------
>tr|D9WQ64|D9WQ64_9ACTN Modular polyketide synthase (Fragment) OS=Streptomyces himastatinicus ATCC 53653 GN=SSOG_05738 PE=4 SV=1
-------------------STADGWRYGVSWRPVRDRSA-GAPGGCWVVVVPAGEWSAGVVRMLERGVDVRLVELGAEAERG------------AVAEQL
RAAVV--GASVAGVVSLLAVEGDA--------------ALLRTAALTQALGDAGMGAPLWVATRGAVSVGSDGAVCPDQALVWGLGRVAALELPERWGGL
VDLPESVDE---RALARLAGVLAGGGGEDQVAVRASGVFGRRLVRASAAVSS--GGSWRPGGGSVLVTGGTGALGARVARWLVAAGAEHVVLSSRRGLDA
PG------AVELRDELSASGARVTVAACDVADRDALAELLASLPDE--LPLTAVIHTAGVLDDGVVDGLDAERVERVLRAKVASARNLHELTRDLDLSAF
VLFSSLAATVGAPGQGNYAAANAYLDALAERRR-AQGLPATSIAWGPWAEGGMAADDALERRMRRDGVPPMAPEVALTALQQALDHDDTAVVADIDWDRF
LAEFTAV----------------------RPSALFGELPAARP------VPAAA----ERP--TATGAGTGTLAERLSGLT----GTERAQTVLELVRTQ
VAAVLGHEAVVAGRAFKELGFDSLTAVELRNRLNAATGLRLPATLIYDYPNATALADHLRTEL---------
>tr|A0A060ZDD0|A0A060ZDD0_9ACTN Beta-ketoacyl synthase OS=Streptomyces iranensis GN=SIRAN1030 PE=4 SV=1
-------------------STIDNWRYRVAWKPVPDAAD-GSLSGTWLVVVPASRLVAEVVTGLRHGADVVSLVDERDLDAE------------ALGERL
RVAIA--DTALGGVLSLLALDEEPCPGHL-----ALSSGLALTLTLVRAMADTGVEASLWCATRGAVSVGSERLSHPAQAMVWALGRVAALELPQLWGGL
VDLPESLDE---RAAARLAGVLSAEVAEDQVAVRGSGVFARRLTRSAAPAAD--GTAWRAR-GTVLVTGGTGALGGQVARWLVRDGAEHLVLTSRRGIEA
PG------AAELREELEALGVRVTVAACDVADREQLAAVLDAVPEE--LPLTAVVHAAGANGTGPLAETGLADAAAVVSGKVAGAVNLDELLGDRELDAF
VVFSSIAGVWGSGGQAAYGAANAYLDALVEDRR-ARGLAGTAVAWGPWAEGGMAAGD----QLARRGLPAMAPGLAIAALRGAVAGDDGVVVADVDWERF
APAFTIG----------------------RPSPLLGDLPEVQR------ALANA-----GS--AEGTSAGSALRERLTGLT----EAEIDRTLLDLVRAH
AAAVLGFDSVEPARAFKELGFDSLTAVEFRNRLNVETGLVLPATLVFDYPSATVLADHLRAEV---------
>tr|A4FDM8|A4FDM8_SACEN Modular polyketide synthase OS=Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 
-------------------GARHELLFQLDWLPLPTVPA-SSAARHWAVVGPDVF----VADSL--------DSQGRSVDRY------------SDADEL
VESVD--SAEAAPEVTVLQVAGTTAGGAASPAEEARDRVRVVTEQAESWLGDEFAEGTLVVVTRAAVAAGDDEVSDLVAAPVWGAVRALRAAHPGRV-VL
VDLDDGG------SAAALAEAVS--SAEPELLLRSGVALRPRANRVAATGGS--RPFQLTSRDTALVAGADGVVAATVARHLAAVDVRRFLLVSRGGDAD
LA------ARELRAELTAAGASVALVACDVADRDALAGLLAGHR-----PAAVVFAAGA----G-----------REALSTMDGALNLHELTLDAGLKAF
VLLSSAAGTLGGAGSADDAAAGVFLDAVARHRA-ARGLPALSVVFGPGEHEDWSV---------PAGVGRLTGREHAAMFDAAHLADRTSVALRPDSTA-
---VGSG----------------------SLPPALRD---LID------VPVQA----DAP----DDGTVSELRERLAPLS----RDEQDRTLVELVRGE
VARLYAMATVPSDRAFRDLGLDSATAVQLRNRLTATTGLDLPLTLAFDHPTPARVGRHLRSLL---------
>tr|A0A0A0NSP2|A0A0A0NSP2_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces rapamycinicus NRRL 5491 GN=M271_45450 PE=4 SV=1
-------------------NAHHDALFRTRWVPQPSAPQ-PPRPGRWVLLGRHAP----FVGLL--------RAIGTELGEH------------VDTVDL
RAAVA--AGSPPPAVALLS-----APA---------DTTEGVLRDVETWLASALSDALLVVVTQSAVATTGEDVPNPEQAALWGLARSLQAAHPGRI-AI
VDLDAPDDE---TCAGALLAAVA--SGEPQSAVRSGVVLLPRLERVALDMGL--GSVAFDPHGTAVVTGVDTRRGAAIARHLVTGGVRQLLLIAPPGQGG
-R------AYELCTQLTDAGAGVRLVECDLDNRTKLRRALAKATS----PLSVVVHAWE-AVDE-----------PSDGRVVAEARTLYELTRKADLTAF
VLSSSTKGLLGAAGETTEAASAAFLDAYAQHLR-MRGVPAQSIAWGPWEGETD------------ETTGALSSREALAALDAALGVDHAQLAMKLDPTA-
---VPTG----------------------TASPLLQD---LID------VPART----ATV----DEAVTVALRERLMDTH----EADRDRLLTDLVREH
LADLLGLHAVEPERAFTDLGLTSVTVVELRNRLSEATGLRLPATSAFDHPTPVALGSLLRREL---------
>tr|V4HWI5|V4HWI5_9ACTN Beta-ketoacyl synthase OS=Streptomyces sp. PVA 94-07 GN=B590_00370 PE=4 SV=1
-------------------ARTDDPLFHVRWQPLPPQAT-PSPSTPWGILGQDTL----LRPALDAGSSPTSYE---------------------SLSDI
G--------ETVPATVLLPV---PEGGADDPPGRVHALFSSVLATLREWLADEFSAARLVVVTRGAVLTGGGDAPDPVAASVWGLLRTAQTEHPDRFVLL
-DLDTGAGT---ETADALATALGTG--APQLAVRSGTAFAPSLVRGTEPAPP---TRPIDTSGTVLVTGALGTLGRLTTRHLVTEGVRHLLLTSRTGPAT
EG------ADTLRAELAELGAEATLVACDTADRAAVAELLAAVPDE--HPLSAIVHVAGVLDDAVLEALTPEQVAAVLRPKVDAAWHLHELTRDLDLSAF
VLFSSAAATFGNAGQANYAAANAFLDALAGYRR-ARGLTATSMAWGLWAEASGMTDHTDLQRLARLGVTPLTSTAGLMAFDEALRLNRPAVPMGLDTRRL
A-AADAA----------------------SLPPLLAPYARATP------VRRRN-----AA--ATSPASATGLLDRLRSLT----AQQQLDTLLGMVKRH
VVSVLGGASVRTQTSFKSLGFDSLTSVELRNRLNKETGLRLPATLAFDRPNPAAVADFLQREL---------
>tr|E8W293|E8W293_STRFA Amino acid adenylation domain protein OS=Streptomyces pratensis (strain ATCC 33331 / IAF-45CD) GN=Sfla_0142 PE=4 SV=1
-----------------ARTTIDSWLTEPVWTDCPPLPAHAARDHGWLILADTGGVADAFAALAARGERCRLVRRGPAYTASDGSTYTVDPASDSGLRRL
LADLDRDGGPFRTVLHLWNLDAPALAADRDTLRDHTGAGAYSLVVLARLLAARGGGGRLHIVTRGAQPALPGEGPEPLGAPAWGIGRVLRQELIGHPGKL
VDLDPRRQQGDRADAEALLAEAL-SDDEEEIALRHGGRRTSRLRPAEALTR--PLPLRLRADGSYLVTGAFGALGRLLCRTLVRRGARRLVLVGRTPVPP
RAAWAARAVHLL-RELEALGARPVLATLDITEEDALADWLDAHRRSGAPPVRGVFHLAGQVRDTLVADLDRDTFDTVHDPKTVGAHLLHRHLRDEPLDHF
VLFASIASLLTTAGQTNYAAGNAFLDALAHHRR-AQGLPGLSLDWGPWA-TGMIEELGLDHYLHSRGMSSLSPDAGMAVLERVIGQDHAQLVVVVDWPAF
LA------------------WYPS------PPPLVADLAA----AASP--PRD-------AVSGNGFLDS------F---RA-ADPQTRRALVAERFAAL
AATVLGADRIDPAAGLGELGLDSLLAMELRARVHAELGVALPLVALLSGSPAGELATQLHDG----------
>tr|A9YLB5|A9YLB5_9ACTN AngAIV OS=Streptomyces eurythermus GN=angAIV PE=4 SV=1
-------------------AGIEAWRHKVVWKGLPTEET-ARLSGRWLLVLPEGGPADDIADVLRHGATVR--------------RLVADPVALG-RDGL
AARI---SGTWDGILSLLPADERPHPAH-----PSLDRATVGTVLLAQAVSDIGTGARLWTVTRRAVAVAAGEEPSTAGAQVWGVGRGIALELPTVWGGL
VDLPDAPDA---RCLRRLAWVLAAAGAEDQVAVRASGAYGRRLAPAGGAAG---EGRAYTPRGTVLVTGGTGALGGHVARWLAVNGAEHLVLTSRRGQDA
PGA--AALTAEL----EARGVRVTVVACDVSDCAALAALLDEH------PPTAVFHTAGVPHSGAFLDLRTDGMADVYGGKVTGARHLDELTRERDLDAF
VLYTSGAGVWGSGGQTAYGAANAALDALAERRR-AGGLPATAIAWGLWAGGGMGEGDG-EEFLSERGLRAMPPESALESLGVALERGDTCVVAHVDWPRF
ARSFTA---------------FR-------PSPLIGDLAGT-GGAG-ERY----------GDGEESTGDQ-GFLARYTA----CGPVERREMLLDLVRRQ
VAAVLGHEEVPADQAFRDLGFSSLTAVEAATRLGRAVGAKLPPTLVFDHPTAEAVGDHLAEVL---------
>tr|A0A0F7C8U1|A0A0F7C8U1_9ACTN Polyketide synthase type 1 OS=Salinispora pacifica GN=spr10 PE=4 SV=1
-------------------TTADGWCYRVGWKRLERAD--DPLTGRWLLVTGPDP---LVEAALARGAQVQ--------------HLTVDPATAD-RASL
GALLAAGGSGASGVLSLLGSDRRPHPDH-----PDVSVGTTATLLLTQAVADAVPTARLWTVTRGALAVAPTEVPDEHQAQVWGLGRVAALELPQLWGGV
VDLPVASDE---QIWDGLADVL--AGAEDQVALRGPAAYGRRLRRAPA-LP---PKRSYRPRGTVLVTGGTGALGTHIARRLAADGAAHLVLTSRRGADT
PGA--ADLVEEL----RALGAEVTVAACDVADRAAVADLLDGLPV--TDPLTAVFHTAGVAHSVPVTETGLPDVAEVFAGKVAGARNLDELTRGYDLDAF
VLYSSNAGVWGSGGQSAYGAANAALDALAERRR-AEGLTATSIAWGLWGAGGMGEGSA-EAYLSRRGLRPMSPEKGVDALLAALDRDETFVVADVDWDLF
TAGFTA---------------FR-------PSPLIGDLPEV-RAVL-ADS----------TGQEGASIGS-DLLDRLAA----ADREDCHRILLDLVRRH
VAAVLGHEHIDPHAAFREIGFDSLTAVDLAKRLKAAIGVPLPATLVFDHPTTMAVAEHLIGLV---------
>tr|A0A014KX73|A0A014KX73_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. PRh5 GN=Z951_46245 PE=4 SV=1
------------------RSTIDSWRYRVAWKHLPDPATAPTLSGTWLLLVPSG-LEEHVQALDAHGA---------AHEALSLDGVE---ARRDALAPL
LSHL-PDGSTPEGILSLLALDQTPHPD-----HPAVPTGLAATAAVVQALGQTPLIAPLWCVTQGAVAATATPLPHPHQAQIWGMGRVAALEHPHLWGGL
IDLPADVDART---PARIAAVLAPGQPEDQVAIRATA-LARRLERAACPDT---APTAWRPAGTTLITGGTGGLGAHVARWLARHGAPHLHLISRSGPDA
PGA--TQLAQEL----TDLGTTVTITACDASDRTALRHLLDTTPAE--HPLTTVIHAAGLAENTPLAELDLPGIAAVLRPKALAAAHLHELTEDLDLSAF
VLFSSGAAAWGGSRQPSYAAANAYLDALAEHRR-ARGLPATSLAWAPWSDAGMAADEAVIDYYRRRGMRPLDTDLAIASLQHALDHADTTTIADIDWARF
PAGFTAQR----------------------PSPLLSDLVAT-------ASPGA----DATP-----DVDA-TLSSSLQQLT-TGSPAQQHQLLLHHIQTH
AAAILGHDAVPPAQPFQELGFDSLTAVEFGHRLSAATGLDLPPTLVFDHPTPKELADYLRERL---------
>tr|A0A060ZJ24|A0A060ZJ24_9ACTN Beta-ketoacyl synthase OS=Streptomyces iranensis GN=SIRAN149 PE=4 SV=1
-------------------SAVQDWFYRVTWQPAAMPEN-AGPEGRWLALLPRDGAGEVLLGLVAQGMRISRITVGDI-------------------DGL
AERLA--GSAPQGVLSLLALDETPDPDHPA-----MARGTLLTAATIRVLGEAGIEAPLWCVTAGAVATDADPVRNPVQSQVWGLGRVAALEHPERWGGL
VDLPGMPDE---QTFVRMAAVLSGGGDEDQIALRNPGVLVRRLVRAEPVSG--RAGGGWRPRGTVLITGGTGALGRQVAHWLAGNGAGHIVLTSRSGKNA
PG--AMELADAL----IGRGVKVTVAACDVTDRQAVSELVAGL-----PELTAVVHAAGVGAYRSLAESSAADIAGVMAAKVAGAAHLDEILGDRELDAF
VLFSSVAGIWGSGRQSAYAAANAYLDALAQNRR-SRGLAGTAVAWGPWGGGGLVSDRDVAGRLSRLGLDQLAPGQALTALGMALERDEPTVVADVDWARF
APAF------------------TAN----RARPLIGELPE-VRQAL----------------ADDE-PAEVSLRDELAGM----PREQAAGVLLDMVRTN
AATVLGLATVEPDRPFRELGFDSLTAVELRTRLGAATGLRLPATVVFDYPTPVALAGHLGAGL---------
>tr|A0A060ZAR4|A0A060ZAR4_9ACTN Beta-ketoacyl synthase OS=Streptomyces iranensis GN=SIRAN146 PE=4 SV=1
-------------------VAVADLYPRLAEAGYYGPVF-QGLTSVWRAVDPLDSAAEFLFGVAATGAPAVRVRMAGS-------------------DAV
SVELA--DGAPSPHESLFRVTWVPVPETGD-----DGAETVLVEATAEALGAETKPGRLVFVTRGAVAADGDDVTDPAGAAVWGLVRSAEAENPGRFAL-
VDLDGDGTV---RL----------PVGEPQVAVRRGKVLAPRLARTA--AD--GEPVRLDPRGTVLVTGGTGMLGGLIARLVSAYGVRNLMLISRRGPHG
PG--VDDLVADL----AERGARATVVACDAADREALAATLATI-----PALTAIVHTAGVLDDALLESTTRQRLAAVLRPKVDAAVNLAELTEDERLAAF
VLFSSAAAVLGGAGQGAYAAANAFLDAFAQQRQ-ARGAIVSSLGWGLWAPPSEMTGHLDAARLARAAMVPLTGEEGLALFDAALATGAAHTPARVNLATL
---R------------------RDG----AIPPLLSGLVARGRRAA----------------SASG-TADPGLAERLAGM----PEAEGSAYLLGLVRSH
VATVLGRDDVDAGRAFKDLGFDSLTAVDLRNRLGAATGLRLPATVVFDHPNATGLAGFLRAEL---------
>tr|A0A0Q7TR69|A0A0Q7TR69_9ACTN Non-ribosomal peptide synthetase OS=Streptomyces sp. Root55 GN=ASD51_21175 PE=4 SV=1
-----------------ARTTIDSWLAEPVWTDCPPLPVPAARDHGWLVLADTRGVADAFAALAARGERCRLVRRGLAYAASDGSTYTLDPASDLDLRRL
FADLDRDGGPLGTVLHLWNLDAPALAEDRAALRDHTGAGAYSLVVLARLLSARDGEGRLHIVTRGAQPALPGEGPEPFGAPAWGIGRVLRQELIGHAGKI
VDLDPRRQPGNRADAEALLAEAL-SDDEEEIALRDGGRRTSRLRPAEALTR--PLPLRLRTDGSYLVTGAFGALGRLLCRTLVRRGARRLVLVGRTPVPP
REKWAGRAVRLLR-ELEALGAQPVLATLDITEEDALADWLDVDRRSGAPPIRGVFHLAGQVRDRLVADLDRNAFDAVHDPKTVGAHLLHRHLRGEPLEHF
VLFASIASLLTTAGQTNYAAGNAFLDSLAHHRR-AQGLPALSLDWGPWA-TGMIEELGLDHYLHSRGMSSLSPDAGMAVLERVIGQEHAQLVVVVDWPVF
LA------------------WYPS------PPPLVADLAAA-------AAPPR----D--AASGNGFLDT---------FR-AADPQTRRTLVAERFTEL
SATVLGTDRIDPTTGLGELGLDSLLAMELRARIHAELGVALPVVALLSGTPAGELAAQLHDG----------
>tr|B5GIC0|B5GIC0_STRSH Non-ribosomal peptide synthetase OS=Streptomyces sp. (strain SPB074) GN=SSBG_04126 PE=4 SV=2
-----------------SRATVDSWLALPEWVPLPGLAPAAEGPRDWLVLADTTGLADAFAALVERGDRCRLVRPGPGYAREETGDVTLAPEDPVHLDRL
FAELDGEGAPFREVVHLWNLGLPGLAESGADIGTATARGAWTLVALARVLRARRDTCRLHVVTRGAQPVAAGDAVEPLGAPAWGVTRVLRQELARHRGKL
VDLDPVRATPP-DEAAALLAEFLA-DDEEEIGLRGNTRATLRLQPAAPRLTG-PLPPRLRPDGTYLVTGAFGALGRLLCRTLVRRGARRLVLLGRTPLPP
RAAWRTQAIALV-REIEALGASVVLAPVDLTDEAAFTGWLATYRAGDPPPLRGVFHLAGQVRDTLLADIDRAAFDTVHAPKTTGAHLLDKHLRDEPLEHF
VLFASVASLLTTAGQTNYAAGNAFLDALAHRRR-AAGLPALSLDWGPWA-TGMIEELGLEHYLHSRGMSSLSPEAGMSVLERVLGQDLAQLVVVVDWRTF
LA------------------WYDT--P----PALVQDLAAS----A-GD---------------RAAEDEGDLLAAF---RA-AGPEERRALVAERFTRL
VATVLRAEEIDPAGGLGAHGLDSLLAMELRARSQAELGVAPPVVALLSDTPVAELAARLHEELTE-------
>tr|Q27W68|Q27W68_STRVO NigAVI OS=Streptomyces violaceusniger PE=4 SV=1
------------------RSAVDSWRHRVEWRPVPDTA--PTTAGSWLVVHPKSGWTDACVALGADGGQVYLLEL--------------DGDDREGLAAL
LRSRYAEETPPTGVLSLLALDEGTPP------LPGVAPGLTGTLTLLQALVDAAVPAPLWCATRGAVSIDDSDPDAPHQAQLWGLGRVAALEHPDRWGGL
VDLPASPDSL---DARRLCALLTGACGEDEAALRPAGAYGRRLIPDPIGGR--APRRIWKPRGTVLITGAADGPAAHVARCLAADGAAHIVMLGPGGGDA
PAA------VELKAELDALGTGLTVADHAPADREATAHLLERVAQA-SGRIGTIVHTAASGELAPLMELTPRRLAEEHAHLDDTGRPLDELCGMGPEDTV
VYFSTVAASWGSKDHGSYAAATACLDALARRDR-AEGRPTVSIAWGLWDLPYGGDATPHTERSRRQGLSPLDPRLALTALRQALDHDDPSVIADVRWERF
APLFTL------------------A----RPSRLFDGVLAARQAIE----------TARGPVEDTVGDEASALRRELGAL----PEDERGERLLALVRAH
VAAVLHYESVEPDRPFKELGFDSIAAVELRNRLRAATGLSLPTTVVFDYPTPRTLAGHLLTEVDPG------
>tr|Q7WTE3|Q7WTE3_9ACTN NanA7 OS=Streptomyces nanchangensis GN=nanA7 PE=4 SV=1
------------------RTTLESWRHQIRWTPLP--P--PAVSSTWLLLVPTGHPAVRTVALTGHGAEVRPCPA--------------DPSSRAELAER
L-TGLRGDDAPAGVVSLLALDERPAD------HPAVPAGLAATVAALQALGDAGITAPLWCVTQGAVSTGHDDPSHPLQAQTWGLGRVAALEHPDRWGGL
VDLPAEPDER---TEAQLAALLAGGQAEDQVAIRAGGGALARRLVHTTSAR--TADQAWQPRGSVLITGGTGGVGALLARWAAERGAAQLVLTSRRGPNA
PGA------AELAAELRGLGVAVTIAACDAADPEAMRGVLDAIPAE--HPLSAVIHAAGVSEQDLIADVDDEHLNRMLAPKALAAWHLHELTRHLDLSAF
ILFSSVSASWGSGQQAGYAAANAYLDALAEHRR-GLGLPTTSVAWGLWGEVGMA---DEVDAFRRRGIHPLDPGLAIASLQQAVERRETNAVAAIDWRRF
LTGFTA------------------L----RPSPLLSDLPEAAEARA----------EET----RPREDEADPLRRKLAGC----PPAEQHHILVRHVQAH
AATTLGHDAVPPTKPFQELGFDSLTAVQLRDRLNAGTGLRLPTTVLFDYPSAEELARHLHGLLVAD------
>tr|G2NTW1|G2NTW1_STRVO Beta-ketoacyl synthase OS=Streptomyces violaceusniger Tu 4113 GN=Strvi_3962 PE=4 SV=1
------------------RSAVDSWRYRVEWRPVTDA----APAGSWFVVHPKGGWTDACVALGADGGRVRGLEL--------------AEDDREGLAEL
LRSRSAEETPPTGVLSLLALDDDARP------LPGVAPGLTGTLTLLQALVDAAVTAPLWCATRGAVAIDDSDPDAPHQAQLWGLGRVAALEHPDWWGGL
VDLPASPDTL---DAERLRALLTGACGEDEAALRPTGAYGRRLVPDPIGGR--APRRTWKPRGTVLITGTADGPAAHVARRLAADGAEHLLMLAPGGGDA
PGA------VELKAELDALGTGLTVADHSPAGQDGTARLVERVAEA-SGRIGTIIHTSASGELAPLMELTPQRLAEERAHLDDTGRRLDELCGMGPEDTV
VYFSTVAASWGSKDHGSYAAATACLDALAHRDR-ADGRPTVSIAWGLWDLPYGGDTPAHTERSRRQGLSPLEPRPALTALRQVLDHDDPRVIADVEWERF
APLFTL------------------A----RPSRLFDAVPAARQAIE----------AARGSAEDTGADEASALRRELGPL----AEDERIERLLALVRAH
VAAVLHYESVEPDRPFKELGFDSIAAVELRNRLRATTGLSLPTTVVFDYPTPRALAGHLLAEVDPG------
>tr|A0A060ZMF5|A0A060ZMF5_9ACTN Acyl transferase OS=Streptomyces iranensis GN=SIRAN1234 PE=4 SV=1
------------------RSAVDTWRYRVEWRPVADAA--PAAVGSWLVVHPKGAWTDACVALGADGGQVRRLEL--------------AEDDREGLAEL
LRSRCAEEPPPTGVLSLLALDDDAPP------LPGVAPGLTGTLTLLQALVDAAVTAPLWCATRGAVSVDDSDPDAPHQAQLWGLGRVAALEHPDRWGGL
VDLPTSPDTL---DAERLRALLTGASGEDEVALRQAGAYVRRLVPDPIGGR--APRRTWRPRGTVLITGTADGPAAQVARHLAADGAEHIVMLCPGGGDA
PGA------VELKAELDALGTGLTVADHAPADREGTARLVGRVAEA-SGRIGTIVHTSASGELAPLMELTPRRLAEERAHLDDTGRHLDELCGMGAGDTV
VYFSTVAASWGSKDHGSYAAAAACLDALARHDR-ADGRSTVSIAWGLWDLPYGGETASHTERSRRQGLSPLDSRPALTALRQVLDHDDPGVLADVAWERF
APLFTL------------------A----RPSRLFDGVPAARQAIE----------AARGPAADTGTDEASALRRELAAL----PGDERAECLLALVRAH
VAAVLHYEAVEPDRPFKELGFDSIAAVELRNRLRAATGLSLPTTVVFDYPTPRTLAGQLLAEVDPG------
>tr|B3PDZ5|B3PDZ5_CELJU MxaD OS=Cellvibrio japonicus (strain Ueda107) GN=mxaD PE=4 SV=1
-------------------SLISDLLYEFRWHEAELERT-AVQEGHVLVVADCSGLGHHIREQLNAGSQVVLWDA--------------QSRNLEDWENL
LKES---ATTCKSIVYLPSLDMDFSDESVDHIAAVVKNGCDGPLPFIQAMLRISRNISLFLVTQGGQSTQHQDINTLSQSTLWGLGRVLSSEHPEFSVVM
VDLDNRDC---ADTIDRLSQEILYGGQEQEIAIRNGARLVNRLGRISNTELPGKVTGIVRPDATYLVTGGLGGLGLAIMDWLVDEGAKSIVLTGRNEPNT
Y---AQQAIARVQ----SQGIIVKVARADVTSESDIQQLVEYINAE-MKPLRGVIHSAGVLDDGVIAQQTPEKFARVLASKVNGSWNLHRATRHCPLDIF
VCFSSIAAVVGWPGQSNYAVANSFMDALCRYRQ-QQGLPALSINWGPWAEVGMASKLDVIDRMESSGMKALNPKAAVLAMQELLAYGVEQAIFDMNWRAV
---------------------FNNS------ASLKS--KTLLSGFL----------------EKNDQSDCVDFASLY----RSTPAPLRAALVQEKSCGI
LADILGFDQIEVTTNLFEYGLNSLMAMDCKNRLQNLFAVKLPATLLLKHPTIAGFSE---------------
>tr|A0A060ZBC6|A0A060ZBC6_9ACTN Beta-ketoacyl synthase OS=Streptomyces iranensis GN=SIRAN154 PE=4 SV=1
------------------EPAFDEWLYRAVWQPAAEIQS-VDGGGTWLAVVPGGGAGDELLAGLA--------GLGMTFRRVA----------VEDIEQL
GD-----EPAPRGVLSLLALDEESHPE-----YPAVGRGLLSTARLVGALEEAGIAAPLWCVTSGGVGTSGDRVRNVAQSQVWGLGRVAALEHPQRWGGL
IDLPEHADD---AAVTLLAQVLTGDGSEDQVAIRRSGVLVRRLARATPT------PGGWNPRGTVLVTGGTGALGSHVARWLAAEGAERVVLVSRQGEAA
PG------ASELTSQLTGLGAEVSVVACDVTDREALGRLVGGL-----PELTAVVHTAGVGAYRSLAESGDRDLAEVMAAKVAGAAHLDDVLDDRDLDAF
VVFSSVAGFWGSGGQGAYAAANAYLDAVVERRR-ARGRSGTSVAWGPWAGDGLAARPGMAQQLGRQGLTLMDPGVALAAMRAVAANDEPVTVADVDWGRF
APAFAA------------------AA----PRKLIGDLPE-VRRAL------------------EG--D-AAL---------SPTPSTSAGDLLDLVSRQ
AAAVLGYATVDPGKAFRDLGFDSLTAVELRTRLAATTGLRLPATVVFDHPTAAALAGHLRAEL---------
>tr|A0A0C5VY19|A0A0C5VY19_9GAMM Polyketide synthase modules-related protein OS=Gynuella sunshinyii YC6258 GN=YC6258_03213 PE=4 SV=1
-------------------STIDNWLTEVHWINKDIPEEATASNGTVLVVGDRRPLIECVSRLRDMRQPFCMVDHDPGFVFEKQSQALFDTASREDWQAF
FGALKDSLPACDGILDLRQLSVPELDCSPETLASQNSYATYPLIAMAQALLASQIQARLLIVTARGQAVLPDEGPNPLAAAAWGVGRVLWQELITNRGSL
LDVDWQQGDGATEAVEHILTELRADVYEGEVAWRQNQRYACRLRAAENLGR--PLPLQLRPDACYLVTGAFGALGQLLCHTLVDRGARRLILMGRTALPE
RSEWSGKQITFVR-SLEAKGVDVITAAVDVSYEESLSAWLQDFRQWQLPPIRGVFHLAGQVRDTLLADMTPESYNAAYDPKVVGSYLLHQYLHDQPLDYF
VMFASVASLLTTAGQTNYAAGNAFLDALAHYRR-SQGLPGLALDWGPWA-TGMIEDLGLIHYRNSRGMNSTAPEAGMDIVERVLGQDVPQLMINVDWPLF
N-------------------------------AWYQEMPPI------------IAELASSQQQAAGDEDHGSFLERYRWA----DESDRQTLLEEHFVFV
VSDVLRISGVSMASNLNDLGLDSLLAIELRARIQRDIKVSLPVVTLLSGTPVSDLIAQVEG-----------
>tr|Q21E99|Q21E99_SACD2 Amino acid adenylation OS=Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) GN=Sde_3725 PE=4 SV=1
-------------------ATIDSWLTEVNWIEAPVKA--TTTEGCTLVFGDAQPLAAVVKTFKLRNQPYCVVSAGEQFNFQELNKATVQANNQADLETL
ISSIE--NTKCEAILYLWQLDAPQLECELEQLDASHSYNTYPLITLAKALGAIKNNARLIVATRSAQAVSTTDIPQPLPAAAWGAGRVLWQELVDNRGKL
VDLDQHHADSDAHIADQLLHE----QDEAEVAWRNNQRFCARLQPATNLSR--PLPLRLRTDGCYLVTGALGALGRLVCQTLVKRGARRIILMGRTAIPP
RKEWHKSHIEFIQ-QLEANGAEAILAPVDVTNEHSISSWLADFKEQGRPPIRGVFHLAGQVRDTLIAEMQPETYNAAYNPKVLGSYLLHRHLAAEPLDHF
VMFASVASLLTTAGQTNYAAGNAFLDVLAHHRR-AQGLPGLAIDWGPWA-TGMIEELGLIHYRNSRGMSSLSPEAGMDVLERVMGQNHAQLMVNIDWPLF
T-------------------------------AWYPTLPPL------------IVDLAAQQKEAQGETDQGAFIDRFKQA----DESQRFALLSEHFTHV
VSDVLRIELVTAESSLNDLGLDSLLAIELRARIQRDMKVALPVVTLLSGTVVNELINKINT-----------
>tr|L8P1R0|L8P1R0_STRVR Putative Modular polyketide synthase OS=Streptomyces viridochromogenes Tue57 GN=STVIR_8608 PE=4 SV=1
---------------LAALSPLDGALFETRWQPRPVADE-PPGRGGWLILADDSGVAAGLVERLGTSVPCVVARRGVEFAAEGHGRYVLDPADPQHLARL
LDEAFP-SEMPERVVQLSALDAPAIED-AHTAGAAARLCCLSTLHLVRALADRGPAPRLFVVVRGSQPAGDSRVAHPQQALAWGFGLALAQEHPELRTTL
VDLPPTDG------LDALCTQLRHADDERLVALRGAGRLVPRLARTRPDDGG---HGAVGPDGVYLITGGLGGLGRVVAERLVRRGARRLALLSRSTPTA
EA---ADWARGL----AERGVAVHLARADVADRDGLSAALDAVRHE-LGPVTAVIHAAGVLDDATLANLTDERVLRVLAPKVLGTALLTELIPEAR--DL
ILFASAAGLLGSAGQSPYSAANAFLDAWAHHLS-HTDRRALSLDWGAWSGVGMVSGSGARAETARSGLVAFSRQDGGELFDRVLTTARRQLPLALDWEML
ALDP--------------------D--AARTRPLLADL-------V------------TAP---TGTPGTDDLVKSVF---AAPTDAERALRLEAYVRSR
VGEVSGAVQVSATTALKELGLDSLMLVRLRNAFARELGVELPAATVFSAADIRGLARALSTAL---------
>tr|D9T6X0|D9T6X0_MICAI Acyl transferase OS=Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442) GN=Micau_2470
-----------------RQADIDSWRYQDTWKPLTGVAN-RGMDGTWVVVLPTGDIIEPWQAFAAAGATLVPVAVSTP------------DVDRDQFGKL
LRELAAAPAEVTGVVSLLAFDELAHP-----LHPSVPGGFAATVALFQALGDIGLRAPMWSVTSGAASVGMDLLRSPVQSLVWGFGRVAALEHPQRWGGL
VDLPEAVED---RCADLLVAALTTAGDEDQIAVRPTGLLARRLTRVPLGDSQ--PANPWQPYGTALVTGGTGALGGHAARWLARSGVENIVVVSRRGMAA
PG--AQQLVDDLT----ALGAQAVVAECDASDREALAELIDQIPAEY--PLTVVVHASAVLDDAMINDIRPEQIERVLQAKVDVAYNLHELTLDHELSAF
VMFSSFAGSVASSGVGNYAPSNAFLDALAQHRR-GLGLTATSIAWGAWAGGGMADGP-LGDLLHRHGVPEMTPEAAITALHQAVDHGEAFLIADIAWERF
SVAFTAT------------------RP----GPLISDLPDV-R-RLAA--------AEAVASVEVGD-GPESLRDRLAGLP----ATERFAVLLGLVRSQ
VAAVLNYESVDEHRAFRELGFDSVTAVELRNRLGSATAVALPVTLVFDYPTPTTLAEYLYAEVAHDDVVTP-
>tr|A0A0D0X4V4|A0A0D0X4V4_9ACTN Acyl transferase OS=Micromonospora carbonacea GN=TK50_11440 PE=4 SV=1
-----------------RQSDIDSWRYQDTWKPLTGIAN-RGMSGTWVVVLPTGDIVEPWQAVTAAGATVVAVPVSTT------------DADRDLLGKL
LRELAASGADVTGVVSLLAFDELVHP-----LHPSVPGGFAATVALFQALGDIGLRAPMWAVTSGAASVGRDLLRSPTQALVWGFGRVAALEHPQRWGGL
VDLPEAVDE---RCAGLLVAALTAAGDEDQIAVRPGGLLARRLTRVPLGDSQ--PANPWEPYGTALVTGGTGALGGHAARWLARSGVQNIVVASRRGMNA
PG--AQQLVDDLT----ALGAQASVVECDAADRDALAALIESIPAEY--PLTTVVHASAVLDDAMINDIRLDQIERVLQAKVDVAYHLHELTLDLDLSAF
VMFSSFAGSVASSGVGNYAPSNAFLDALAQHRR-GLGLPATSIAWGAWAGGGMADGP-LGELLHRHGVPEMAPDAAIAALHQAVDHGEAFLIADIAWERF
SVAFTAT------------------RP----GPLISDLPDV-R-RLQA--------TERIATVETGD-GPDSLQERLAGLP----AADRLAVLLGLVRGQ
VAAVLNYESVDEHRAFRELGFDSVTAVELRNRLGSATGVALPVTLVFDYPTPTTLAEYLFAEVAHDDVVTP-
>tr|H0KB74|H0KB74_9PSEU Beta-ketoacyl synthase (Fragment) OS=Saccharomonospora azurea SZMC 14600 GN=SZMC14600_21943 PE=4 SV=1
-----------------RSASLQSWQYRISWRPVRLPEP--RPQGDWLIVVPSGPVDDDLLSVFGE--RATVVES-------------------ADRQTL
ATRLREVDEAPKAVVSLL-------------------TDVVDLLALVQAMGDARIEARVWAVTRGAVSTPGERVEDPAQAQLWGFGRVAALEQPDRWGGL
IDLPVDADA---GTCARMLGVL--EADEDQVAVRRSGVFARRLVRVTEPV-----ESPWQPRGTVLITGGTGALGGHVARWAAANGAEHLVLVSRRGPAA
EG------AEALTAELRELGAEVTVVACDLTDREAVAELVRD------TPPSAVVHAAGVLDDGVIEGLTPDRVRGVLRAKVDGATLLHESTGD--LDAF
VVFSAFAGAIGSAGQASYAAANAHLDALIEQRR-ADGLPGTAIAWGPWAGEGMAAGVA--DDLAALGLPALDPGSAVQALADAVGSTHPAVVADVDWPRF
GPLL--G------------------------GRLLAELPDAA---V--AEPARR---EPAPDSLAGA---------VAGLS----RQQQEARVLEVVRAE
AATVLGYESVTSDRAFRELGFDSLTAVELRNALGTVTGLSLPSSLVFDYPTPAALAAWLCDEL---------
>tr|Q8GBX7|Q8GBX7_SORCE Polyketide synthase (Fragment) OS=Sorangium cellulosum GN=spiG PE=4 SV=1
------------------QSTIDAWRYRVAWRALTAPPK-GDIAGTWLVVAPEVALADGVARALARGARGVLVP-----------------VDAEDAAPL
AGRLRAGGQAIRGVISFAALDERPAP-----LEPSVPLGLAVSLGLVQALGDAAIDAPLWLVTRGAVAVGASRVTRPLQAMTWGLGRVVALEHPERWGGL
VDLGEESAPDANNVHDRLANLVARRDDEDQLALRAAGTYVRRLVRAPHDGA---RPPAFAPRGAALVTGGTGALGAHVARWLARIGAEHIVLASRRGAAA
PGA--AALAEE----LSALGARVTLAACDVADREAVAALVRDVEA-GGATVRAVFHAGGAMHEAPVAAMRVEELADAIAAKARGAQHLHDVFAQRPLDAF
VLFSSGAGVWGGGRQGAYAAANAFLDALAEARR-ADGLAATSIAWGAWAGGGMLATD-AERRLKHRGVAPMDPELAVAALAHALDHAETCLVADVDWARF
APSF------------------ASARP----RPLLDELAEA-RSAL--------DALREPPRTAAGPEPASTLRTTLAAL----PEGERHRHLLALVRTE
TAAVLGHSRVEPNRGFFDLGLDSLMSVELRRRVQRATGIKLPATLAFDHPTPSALASKVLAA----------
>tr|G8YZM3|G8YZM3_STIAU Trans-AT type I polyketide synthase OS=Stigmatella aurantiaca GN=rizC PE=4 SV=1
--------------------------------------------------------------------VLVLVEPGETYARLDEHHYRINPAQLGDYQRL
RSELANRGIDPRLLVHGRFAPSSRH---VGSHPGRVAEGLSSLLLIVQGFGLEGLPRRLVHIFE---STPGE--TPPAHAACAGLLRTIERESPKWRCAN
VEIQGSLIESGPRIAQLISAEAMGVDNDVEVRYSGNRRLVRRFKPAAVTGSA--DLLAQMSGKVCLITGGAGGIGAHLAQFLTRAQGARAVLCGRSPAAS
ID----RRVASL------LGERVVYMQADVTKVEDVRRVVAKTRER-FGQIDGVLHAAGVLRDALILNKTLDAAHEVLATKIDGALLLDEATREDRLSFF
ALFSSLSAVTGSLGQSDYAFANRFLDAFAEHRESLRSGRTLSVNWPLWQEGGMRIDERVEEMRERFGLEPIMSEQGGTALLESLQGRAAQLILGGDAARF
QSAFAV-------------------------AGLFDV--------GTSKEPSQVAPPVPSPRT---PVDR----------------GASFERMTAVVRNL
VAQELGIERIGLGESFQRYGMDSVLAVSIAHELDKQFG-EIPKTLLFEHHNLGALADWIATHRS--------
>tr|F0SIS4|F0SIS4_RUBBR 6-methylsalicylic acid synthase., 6-deoxyerythronolide-B synthase OS=Rubinisphaera brasiliensis (strain ATCC 49424 / DSM 5305 / JCM 21570 / NBRC 103401 / IFAM 1448) GN=Plabr_3151 PE=4 SV=1
----------------SRKDQPTRLLYDIRWQDYRLPDN-SLDPKTWLVVAASEQAADALGMLLERGHRAVHVDLGESGELEQEGRFLIDGHDASQWTQL
LTELKAADISLDGI--AWHIDSKSDQSP----LAVADQHCMSVITAINAFTKAGIECGFQIVTCDGVSTGASLPVIPAHSQFWGFGRSLAAEQPTFQIRL
VDQSSAVDSDSSPKAAFLADYVLNSTPENQIAIRNGQYFIPRLQRVSSDEAE-QVNFPISSEGACLITGGLGMLGQETARWLAAQGAGHLVLVSRRPPNE
A---TVATIEEIR----SAGTEITVAQADSSDREAMSALLKRFGT-DLPPLKGVVHAAGVLQDGLIADQTSERFEKVLSPKVIGAQLLHELTEPMELDFF
ILYSSAASMLGSPGQTNYSTANGYLDGLAQSRI-QAGLPALSLNWGPWT-IGMAADENIARRMELQGIVPLDVS-AHQVLPHALSQGISQLVLDVDWRRL
NAASGG------MSP-----------------PLLADVM-----------PAR--------KRSAGA--SSEFIKKLRAL----PVHERRDSLRDSIQLE
FQAILGSDELATDRPVIEFGLDSLMAVEFSSRLQSLVGEEIAPTMLFDYPTIDAITGYVLEQLGDDETPSP-
>tr|K1V729|K1V729_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. SM8 GN=SM8_04255 PE=4 SV=1
--------------------ATRHPLSRIEWRPAAAPPAPPDTTGTWVVLRHDDRLADETGRLLRTGARVVDAYLEAPAGREGHDHHVLADTGEAAFRGL
WE---AVGEEVAGVVHLGNSGPVR------AEDTELATGPYGCAAALKTLGERQRRARFLVVTHAAQPVADGDRPVPARAALWGLMRTAAVEYPGLRPRL
LDLDEESE-------PALAAELGDG--PPETGYRHGVRHEPVRVPTRPGAT---GTPPVRRGGHYLILGGHGGLGLALAERLAHEGAAVVALASRSGGAS
TGH---PPSQQI----EGTACSLRSYAVDVTAPGALTDLVGRIRAD-IGELHGVVHAAGTLKDGLLRSATAEDLAAVMRPKVDGVRELAAAVAGSELDFA
VLFASVSGAFGNLGQGGYAAANAYLDGFAHAH----GAPWTSVDWGLWGETGMGTAV--AAQLRRRGVRPLGTTEALDALLAVLGDPPRQVVIAHDASDT
-----------------------------------------LADEEPPPAPVR--------A-PAGK---------------APTPHAQRARVEDALARF
LTDRLGLASFDRATPLADHGMSSIMSVELAEELSRRWDVHLPATLFLEYGGLTELAEALTERYG--------
>tr|D7C3U7|D7C3U7_STRBB Modular polyketide synthase OS=Streptomyces bingchenggensis (strain BCW-1) GN=pks7-2 PE=4 SV=1
-------------------SPLDGSLFETRWLPRSAAREL-PTRGSWLILSDESGVGAALSGLLGPAPH-VVARRGDSFAAEAPGRYRLDPLNPEHLARL
LEEAFPE-GPPERVVQLSALDAPAID-SAEAATRVARLCCLTTLHLVRALAERGRAPRLFLVVRGAQAAVSTEVTHPQQALGWGFGLAVAQEYPELAATL
IDLPTDGG------LDALWTQLRHADDERLVALRGTGRLVPRLVRTRPDDA---GRGDIGPDGTYLITGGLGGLGRVVAECLVRRGARRLALLSRGAPAP
E---AARWLEAL----RGRGVTVCHARADVADRQGLTAALDGLRRE-LGPVTSIVHTAGVLDDATLPNLTDERVERVLAPKVLGTALLTELVPE--AERL
VLFSSAAGLLGSAGQSAYCAANAFLDAWAHHLA-RADRSALSLDWGAWTGVGLVAESDTRASVGRSGLIGFSPQEGGELFERLLPTARRQLPLALDWAAL
ASDPDV----------------A------RSRPLLSDLATA---------------LDAAPAAAAGA---DGLVERVL---TATTARERTDRLEAYVRAR
VGEVAGVMDAAPTTALKELGLDSLMIVRLRNAFTRDLGVELPTSAVFSAADIRGLARDLGSA----------
>tr|A0A014KXC5|A0A014KXC5_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. PRh5 GN=Z951_46005 PE=4 SV=1
-----------------DRSTIDGWRYRVSWKPVPDAAEG-SLSGTWLVVVPASRAGDELVGLERHGAGVVSLVADERDL--G-------------AGVL
AARLRAEVPELGGVLSLLALEEEPCPGY-----PGLSGGYALSLVLAQAMVEVDVPARLWCGTRGAVSVGRDRLAGAVQSQVWGLGRVVGLEHSAVWGGL
VDVPESLDE---RGVARLAGVLSAGDGEDQVAVRGSGVFARRLVRADAGE---GAERPWRARGTALVTGGTGALGGRVARWLARSGAEHLVLTSRRGLDA
PGA------TELRDELEALGARVTVVACDVTDREALAGVLASVPEE--FPLSAVFHAAGVEQAAELRGMSLSDAAAVVSGKAAGATCLDELLGDRELDAF
VVFSSIAGVWGSGGQAAYGAANAYLDALVEDRR-ARGLAGTSVAWGPWAEGGMAAAEGVESELARRGLLALDPALALAALRGAIAGDDGVTVADMDWERF
APSFTLGR----------------------PSPLIGDLPEV-AKAL-----------EAV-SASGGAHTSAGLRERLTGLT----EAETDRVLLDLVRGH
VAAVLGFEVVEPDRAFKELGFDSLTAVEFRNRLMAETGLVLPATLVFDYPSAAVLADHLRAEV---------
>tr|D1GLV7|D1GLV7_9ACTN Polyketide synthase type I OS=Streptomyces lydicus GN=slgA3 PE=4 SV=1
-----------------DAEPGADWFHRLAWHPLTDRATAPAPTGTWLVVAPARRPDDALVALEEGGAEVVLVEPARAAA--G-------------AASL
ADRLHAGGRQIEGVLSLLGLAEGEGPGH-----PGTAPGPALTLELLRALDAGDVPAPVWVATRGAVSVGRDRPADPAQAQTWGLGRAAAREAADRWGGL
VDLPVDLDV---RARARLRAVLAGAIPENEVALRPSGAYARRLVPAPPAT---GRAPAWTTRGTALLTDVTTPEGPHLARWLARAGAEHLVLLAPPGTDT
PE--------QLADELAELTAEVTVARCDTRDRAALAALLDSLTAG--RPVRTVVHTTGTPHPAPPSGTPRAVLADTLPARVAGAEHLAELLDHDALDAF
VVCSSAAGTWGAEGQAAAAAADAHLSAWAARRR-ESGLPVTVVAWGPWAGNDPTDG-----AATGDGLTPLPPAAAVRALHRILDGGGTRIVADVDWERY
VAGCPAGR----------------------ISPLFRELPPV-QAAL-----------AAH-AAPPGDWTPEELRRRLAGLP----ADQRPALLLELVRAR
SATVLGHRSVGADDDFLDIGFASMTAVELRNQLVADTGVELPPTLIYDCPTPAALATYLLEEV---------
>tr|H6D577|H6D577_9ACTN Modular polyketide synthase OS=Streptomyces albus GN=slnA9 PE=4 SV=1
----------------RERSTLDSWRYGITWKPLTAPAA--RLEGSWLLVTGQDGRAALLAALAAHGAETVVLE--------------TDPLAL-GRTAL
SGQLAEALPELRGILSLVGTGAA--------------NGAASTLLLVQALADASVQLPLWCATRGAVSVGGDAPAEPDQAALWGLGRAVALEQPAVWGGL
IDLPETLDE---RALGRVARVLAGIEEEDQVAIRATGTFGRRLARRPLHDAV--PERVWQPRGTVLVTGGTGGVGAHLARWLADNGAAHLVLTGRRGADA
PGA------AELAAGIRESGTEVTLAACDAADREALAAVLAAVPES--APLTAVVHAAGLPQSTLATDTTYEDFVQLTAGKVEGARHLDALLGDRELDAF
VLFSSSSGVWGAGRHTAYGAANAWLDALAEQRR-TRGLTATSVAWGGWSG-GMMALEGAGEYMRRRGVGEMAPERALAALRQAVEHDETFVVADVDWEKF
APGFTS------------------ERP----SALLTGLPEV-RRALAPAAVAA-------PRQAE--ESASDLVRS---LRA-GTPAEREAQLLGLVRTE
AASVLGHEDVEPGRAFREIGFDSLTVVELRNRLSAATGLKLPTTLVFDHPSPLALARFLGGEL---------
>tr|D9W5P1|D9W5P1_9ACTN Modular polyketide synthase OS=Streptomyces sp. C GN=SSNG_07471 PE=4 SV=1
----------------QARSTLDSWRYKAAWTPLTAAPAPTAPAGTWLIVTPPQGVAGTVAALAAHGVETVVLE--------------TDPAGA-DRGAL
TERLGEALPGLGGVLSLLGLDEA--------------AGATGTHVLVQALADAGITARHWAATRGAVAAGADAPAVPAQARVWGLGRVVALEQPAGWGGL
VDLPATLDQ---RALDRLAKVLAGYGDEDQVAVRTSGVLGRRLVRAPLGDRE--PLRRWEPSGTVLVTGGTGGVGAQVARRLAATGAAHLVLTSRRGAEA
PGA------AELAAGIRALGTDVTLAACDVSDRDQLKAVLDAIPAD--RPLTAVVHAVGVPQYTLGTETTAAEFEQLSAAKVAGAEHLDALLDGTDLDAF
VLFSSNSGVWGAARHTAYASANAYLDALAERRR-ARGLTATSVAWGAWGGGGMMELEGAQEYMRRRGVLEMDPQAALNAMVQAVEHDEAFVVADVDWARF
APGFTS------------------ERP----SPLLTDLVPQ-------AAPTA-------PQPVD--ESSSALVRD---LRA-ATPGERTTLLTDLVRAQ
AAAVLGHEAVEAGRAFRELGFDSLTVVELRNRLTAATGLTLPATLVYDHPNPAALARFLGAEL---------
>tr|Q63KU5|Q63KU5_BURPS Putative peptide synthase/polyketide synthase OS=Burkholderia pseudomallei (strain K96243) GN=BPSS1269 PE=4 SV=1
-------------------RDVAQWCRTVSWRDAPAARA--LPPERWLVFGDEWF------ALA--PAGSVLVREDDAFRAHGDNGYGVRPGEKADCDRL
IARLAEQGGVPAHVVYGWAQTDV-------------DRAFAGLAALLQALGAHPADFRVSLVTKGARSART--LDACAAAAPAGLLKAVRWEYPRIVCRH
IDIDDASDA----TIDALRAELSSEPLPSSIALAGARREAPGFAALPAVA----RDDVLRDGGAYLITGGASGIGLELAAHIASRRDVRLALLSRSPHDE
N----AARFAALD----EAAASVLRLTADVAHAAQLADALRTVRAR-FGRIDGVIHAAGVEASGLLETGTPDAWRRVMAAKVHGARHLFDQLAGDPPDFI
VLCSSLAAVVGGLGQADYAAANGYMDALAQHWR-QRGVAAIAIDWDTWSDTGMAFDHAARTRNDRPGLPGLANREGRALFDLALAHDASRIVISKR----
--------------------GFEQD-------R--------------RDAPTR--------------ARR----------------AAAPGDAQAALVAL
WQELLGVEQVGVDDDFFDLGGHSLLATQLISRVRDQYARSPTLGEFLEEPTIARILRAIDH-----------
>tr|R1FV99|R1FV99_9PSEU Type I polyketide synthase (Fragment) OS=Amycolatopsis vancoresmycina DSM 44592 GN=H480_37415 PE=4 SV=1
-------------------SEVDSWRYRVEWKPVATPSA-PELAGRWLVVVPGAGVPAALA---AHGAPVVTS----EFT------------GAEGY---
-----------AGVVSLLALDET--------------AGAVANLALAKAMAG--SETPLWLLTRGAVT-----GVSPAQAMTWGLGRVIGLELPGIWGGL
VDLPAEPDAT---TAPLLAAALSGVDDEDQLAIGPSGLLVRRLVRAPFTPP----AQRWKPRGTVLITGGTGALGGHVARRLAADGAGHLVLTSRRGPDA
PGA------ADLEAELSTMGTRVTIAACDVADRDALAALLTGLD----EPVRAVVHAAGLPQATAVLDTTPAEFAAVIEGKVAGARNLDELLGD-DLDAF
VLFSSNAGVWGSGGQGAYAAGNAYLDALAEQRR-ARGAAATSVAWGFWGGGGMAGDVELEDQLRRRGLREMAPEAAVEALCQALDAREVFAVADVDWARF
TPGFTLSR----------------------RRPLIEDIPE-VRALL-----------SEEPET-----ERPALARRIAGLG----EAEARRLLLDLVRGQ
AASVLGHDAVPAARAFRELGFDSLTAVEVRNRINAATGLTLPATLVFDHPNPAALAAELHRL----------
>tr|A0A0M8TQ14|A0A0M8TQ14_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. WM4235 GN=ADK55_08560 PE=4 SV=1
------------------------PISRIVWRSAPADAAREPVTGTWVVLHDADGLGARAARLRADGARVVEVGIGPSGPRAGDGDLMLSQPDEEAFRRL
WDEV---GDPIAGVVHLWNAGEVSDGA--QGEETELRLGLYGCLAALRTLGERQRKGRFLVVTRDGQAVADGDRPVPARAALWGFLRTAAIEYSGLRPRL
VDIDRSSD----DALQALLAELGDSDGPTETGYRQGVRRVPVRVRDRSAAAPRSRPGPVRQGGHYLILGGHGGLGLEVADRFARDGAGVVALVSRSGAAA
VDR---QRTAAI----RAHGCEIVSYSADVTTPGALAAVVQRARAE-YGVLHGVVHAAGTLKDGLIRSATAEDIAAVMRPKVDGVRELATAVAGQDLDFA
VLFASVSGTFGNLGQAGYAAANAYLDAFAQA----HGSPWLSIDWGLWGEVGMGTA--VAEQLRRRGVRPLGTAEGLDALIAVLGSRERQVVVAPDAGD-
---EVIEP-------------------------EAAEAEAE------VEAPSVVRARTGVPNTAGGTAGA------------GGSGVGAGEHVADGLERF
LAERLGVASFDRDTPLSDYGMSSIMSVELSEELSRRWGIHLPATLFLEYGEFAELVQALTDRYG--------
>tr|V4JIJ7|V4JIJ7_9GAMM Uncharacterized protein OS=uncultured Thiohalocapsa sp. PB-PSB1 GN=N838_08270 PE=4 SV=1
-----------------NLQTIDSWLYRPQWALKEQEDEEPQLAKAYLIFADLGGQAQRLAELRRRGCAVSLAFPGSSYSAGDLGEFILEPNNIEQLRTC
LQAFATRYPEDSGIIHCIGLDGPPSLDQMKELESLKESHLHSLIFIARVICEADLRCKLWVVTGSGQVVTEGDRINVLAASITGISRVLAQELCDNWGRQ
IDLANQ----GEDLIPAIVSELGSPAEEQEVGHRDGRRYVSRLVPAEGLRPP--FPVRMKPNACYLVAGGFGAIGRLVCRWLIHKGARRILLITRTTFPS
RDSWKSERIAFVN-ELESMGAEILLADVDVTCESELRHYFKDYEQQMYPPIRGVFFCSGVVKDALVSSIEREDFDPVYETKTVGATVLHQCLADTPLDHF
VLFSSIAGQVATAGQVNYAAANTYLDALAQYRC-AIGLPALSINWGPWA-IGMIKELGLADYKNQRGMPPILPEAGIKVLERILDLPDPQLVCDAHWNKV
R-------------------DWYPKR-----PALFKDLG------------------------DEGEVDEQAD-DFLSRYV-YSPSDQRKNLVELEFKKQ
IAQILRTGKIAGTDVIVALGIDSIMGVELNNRMLAHFGTRLSVVKLLGNLSIRALAEELEQKI---------
>tr|H0KA29|H0KA29_9PSEU Modular polyketide synthase (Fragment) OS=Saccharomonospora azurea SZMC 14600 GN=SZMC14600_19899 PE=4 SV=1
--------------------AVSGWRYRVDWEPYSGSTG--VPEGSWLVVARRAEQADAIVAALPDA-DV----------------LVLDDVER---ASL
AARLA--EHTPDGVVSLLDAA--------------------DTLVLLQAVADSEVATRVWAITRDAVSVAPDEAPDPEAAQVWGLARVAALELPSLWGGV
VDLPATADA---DLVATAVSLL--SGGEDQVAVRARGIRVRRLVPAPRTGT----APEPRPWGTTLITGGTGALGAHVARWLARNGTEHLVLCSRRGAEA
--DGAAELVDELR----GLGSDVTVVACDVADRDAVERMLSSLS-DDGAPVQAVVHAAGAAQVTPLTDIGPAEFAEVVAAKVLGARHLHELTED--LSAF
VVFSSIAATWGSGGQSAYAVANAYLDALVERRR-AHGLAGTAIAWGPWAGGGMAAGEA-EDQLRRIGLSALAPERALAALATAEEHGDVVTVADVDWAIF
AP------------------VFTAHR----PSPLLSTIPEA---RV--EEPVH----------AESSPDS-DLARDLRAM----SETARETFLLDLVRSE
GAAVLGYPAIGTEAPFRDLGFDSLTAVELRNRLSEATGLTLSATLVFDYPTPTALAGYLRDELL--------
>tr|J1ZLY7|J1ZLY7_9ACTN Type I polyketide synthase (Fragment) OS=Streptomyces auratus AGR0001 GN=SU9_33888 PE=4 SV=1
-----------------QRSTVDGWRYRIVWRPQPEPEQA-KLAGPWLVVVPADYLDNDLVRALDNGATVLLVLEDSTTDR------------QGVADQL
RNSLV--TGAPSGILSFLALDERPLTEF-----PEVTVGLVQSVALMQALLDADVEAPLWLLTTESAATADDAVRNPLQAAVWGLARVFALEHPKQWGGL
VDLPAALDDRG---AALLSGVLAAGGDEDQLALRGSALLTRRLTRAPLDGGE--PAAPWRTSGAALVTGGTGGLGAHTARLLARSGAEHLVLTSRRGPDA
PGA------AELRDELAALGARVTIAACDVTDADALAELVAQVES-DGPAIRSVVHTAGVGLLVPLADTTLQEFAEGARAKLLGARNLDALFDRDGLDAF
VLYSSVAGTWGSGDHGAYAASNSYVDALAAHRR-ARGLTGTSIAWGIWSPGGMAVDV-VQEQLRWRGIPFMPAHLAVMGLQQALDHDETFLVADIDWERF
VPV------------------FTAAH----RRPLLHEVPEVLRA------------LEADEDTDAAESTSESLRTPLAGLA----PAERERQLSDLVRKQ
VAAVLGYSEVEVGRAFRELGFDSLTAVELRNRLNTATGLKLPATVVFDHPTVKALAGHLETTL---------
>tr|A0A0J8C1S0|A0A0J8C1S0_STRVR Polyketide synthase OS=Streptomyces viridochromogenes GN=ACM01_26010 PE=4 SV=1
---------------------NGRHLYEVAWTAAPDKPA-EVPGTAWAVRGDGSAVMTALRDLRAAGVQV------------------------------
------TDEGADTVVRVWPRTAPDTEP-VE---AAHQ-LAATAVAELQALIADRAPTRTIWVTRGAIAATGDRVPDVAQSVLWGLARGARTEHPDLGLTL
LDLDGGQPP--------LLCAA-AHADEPELALRTGELLAPRLVRARPAPSG--RPSPIPTDGTVLITGGLGAVGRGIARLLAENGVPRLLLTSRRGTGD
PG--ATDVVAEL----AALGAEVEIAPCDVADAAAVAELLARIGD--ESPLRGIVHCAGVLADGVVAELTADRLAQVLRPKVDGAAHLHRLTADRPLDLF
LLVSSAAGVVGNAGQANYAAANVFLDQLAHHRQ-ALGLPGVSVSFGAWAGEGLAADHADLERMARLGHRALTPDQGRELTGLALRREAPHLVAALDLPRL
RAAAP------------T-------------GALWRS-------LL-P-----------APHPAQAG--SRTPADRLARLP----EPERAARVLALVREE
AAHALGLESVRPDQPLRDLGMDSVTAVDLRNRIGTRIGTKLPATLLFDHPTPTRLAEYLLTGA---------
>tr|A0A0G3AUW2|A0A0G3AUW2_9ACTN Polyketide synthase OS=Streptomyces incarnatus GN=ABB07_37695 PE=4 SV=1
---------------------NGRHLYEVAWAAAPEPAA-EAPAGDWTVVGDPSEVGAALRGLEAAGIQH------------------------------
------RDTGAAVLVRFWPRPAEDAEP-AA---AARE-MAEAALADLQTLL-DQAPARTIWVTRGAVAAGRDTVPGLAQSVLWGLARGARAEHPDLGLTL
LDLDDTDPAA------ALIAAV-AQAGEPELAAHAGDLLVPRLVRARTADT---DGARIPTDGTVLITGGLGAVGRHIARFLAERGVPRLLLTSRRGADD
PR--TAEATAEL----AALGAEVEVAACDVADPAALADVLGAVA----GELRGVVHCAGVLDDGVVTELTPERLARVLRPKTDGAVHLHRLTADAGLDLF
LLVSSAAGVVGNAGQANYAAANAFLDQLAHHRR-AQGLPAVSVSFGAWAGEGLAAEHADLERMARLGHRALTPEQGRDLVELALRRGAPHLVAALDLPRL
RETTAGGG-------GSA-------------AALWRS-------LL-P-----------APRTGHGG--ADGLADRLARLP----EAERADRVLDLVREE
ASRALGLESVRPDQPLRELGMDSVTAVELRNRIGVRLGSRLPATLLFDHPTPARLAEHLLATA---------
>tr|A0A059TYE0|A0A059TYE0_9BACT PKS/NRPS hybrid OS=uncultured bacterium 12-5D GN=5d6 PE=4 SV=1
------------------------------------------KPSTYLVFADGGGVAENLTEILGAGGNVVRVKAGEAFVIHGPSEYAVAPDSKDDIKRL
FEELAKSGTHPRFILHCWSLDHADSDDSLESLQNDQRTGVLSGLALAQAVDACGRAPHVYFITRGAQGVLEGGPSRLASAPLTGLVRVANNEQPNTKWTL
IDLDPKRPT---TEMEDLGNELFLGDGELEVAHRDGRRYANRLHNVKADPRPTEDENLFRPDASYLITGGAGGFGLELAKWMARQGARNLVLMSRSGPRD
--DDAKEDFEAM----RAAGINVVDARADVTSREDVQKVLDQIQAE-LPPLRGVIHGAMVLDDEFLIELDNDRFNKVLNPKMLGAWNLHTLTLGLPLEHF
ISFSSFSAVMGAVKQSNYNAGNYFLDSLAAYRH-SHGLPALTFNWGALSGAGFVERNKTAQYLEMIGLKPFNMDETLRVFRRMLPLDPVEVASRVDWNSI
GRLPMIA-----------------------QANMFAPV---ARKHLEG---------------EGGSSVRPRI---LS-----AAPEEQLRLVEDFIAEQ
VAGVFGTSKIDRHTPLTNLGLDSLMAIELMNRIEGELGITLPMGAVLNGPNLKELAVPVLNT----------
>tr|A0A073CFT1|A0A073CFT1_PLAAG McyG OS=Planktothrix agardhii NIVA-CYA 126/8 GN=mcyG PE=4 SV=1
------------------------------------------ISENWLIFTDSHPEKDHLQQLSKNYGSCTIIYQGQNKIKLSQFEYSLNAHQPEQIKAW
FA----ENPSPHRIIYLLNDNHQDQP------ESILLNRCHYLLNLLQAIQKIPNSPKLFVVTQGGQPFELKQPTFVTQSPLWALGRVISLENPELWGGM
IDLDPSADIT--QNIADLLLGLTHSISEDHLLFRNGQAYLGRLVPSTSPPT---KPLTIQAEATYLITGGIGHLGLALAGHLVDLGAKHLILTTRRPFPP
SSEISAKIMENLRI-LEQKGVSVEVCQADVGDFEQIQAIWAKIEKTAY-PLRGVFHLAGVSGRAQLSECTFADLEIVFQAKVRGSWNLHRLSLATKLDYF
VLFSSAGAIWGAKAQGLYDAVSNSMDSLALMRH-LQGLPATTLNWALLAGNGIVSP-DYEDWLKQIGMKEIDLDRAFSVMDAIIESNQTQIVADVDWVRF
KNIYE----------------FQGDK------PLLK--------KLGQS---------QNII--KSVQDSSSTRRLLED----IAPGERREHLFQYIGKQ
VGMILGIKQPDPEQGFSEMGIDSLLSIELKNRLEKGLEVTLPASLVFDFPNIRRLVDYLIQQV---------
>tr|B0JPW1|B0JPW1_MICAN McyG protein OS=Microcystis aeruginosa (strain NIES-843) GN=mcyG PE=4 SV=1
------------------------------------------TAKNWLIFTDIEPQQNTFQQLLKKCDSCRIIYQGEKNTQISSSESCLNANQLQQLEEW
FA----SNPSPDRIIYLLNSTPKEQP------ESILLNRCNYLLNLLKAIQTIPNPPQLFLVTQGAQPFELEQPSLGFQSPLWAMGRVIALENPQLWGGM
LDLDPDVDIN--QNITALLLGLTHAHDEDHLVFRKGQGYVARLLPLKSLET---TTVKIQTEATYLITGGIGHLGLELAEHLVNLGAKHLILTTRRSLPA
RFDSAAQISEKIRK-LEEKGASIEVISADVGNFEAMQAIFTQIEKTAY-PLRGIFHLAGISGRAQLKDCTLQDLEAVFQAKVKGSWNLHQLSLGTQLDYF
VLFSSAGAIWGAKEQGLYDTVSHWLDALAHFRH-LQQLPATTLNWALLAGHGIVSQ-DYEDWLKQIGIREIAPDMALRVMDAIMASNQTQVIADVDWVRF
KNIYQ----------------FKGEK------PLLK--------NLGLS---------EIPI--KSVQESDSVLHLLED----IPLGERREYLLEYVSKQ
VRIILGIKSPDSEQGLIEMGIDSLSSIELKNRLEKGLEVLLPTSLIFDFPNIRRLVDYLFDRI---------
>tr|S3BYC0|S3BYC0_9ACTN Uncharacterized protein OS=Streptomyces sp. HPH0547 GN=HMPREF1486_03510 PE=4 SV=1
-------------------ARTQEWRYRVRWDRLRTGAPSAQRSGTWLLVLPEETATEESKELPPTGAGWLRVLPGTLAGE-GAEVLRVVPVTACTRDGL
AERLRAGAAPLTAVVSLLPLGAADG-----------RGTAASGLALVQALGEAGIDAPLWTLTSGAVSVRADLPPLPEQAQMWGLGRVAALEHPGRVGGL
ADVPPVPDA---RTAGRVLDRIAAGGDEDQIAVRPDGVHVRRLVPAPGTAR---EEAGWTPRGTVLITGGTGALGAHVARHLAASGAAHLVLASRRGADA
PGA------AELEQELSAAGVRVTLAACDVTDRAALARLLEE------HPPQAVVHTAGLPLVKPLDETTPQDLARLWAAKVTGAAHLDELLADRPLDAF
VLFSSVAGVWGVAGQGAYAAANAALDALAERRR-ARGAVATALAWGPWAGGGMLADAGIENEVSRRGLRPLEPGPAARAVTDLAGTGAATTLADVDWTVF
APA------------------FTAL----RPSPLLA--------ALPGAAP--------EPRTEDG-TGTAALRALLER----TAPGERHAELLRAVRER
AADVLGLDALDADRAFRDVGFDSLTAVELRQRLVRDTGLALPTTLVFDHPSAAALTGHLLREL---------
>tr|A0A0A0NWU9|A0A0A0NWU9_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces rapamycinicus NRRL 5491 GN=M271_45210 PE=4 SV=1
-------------------SAVDTWRYQISWKPLPDMDT-PALSGTWLAVVPEGDWAMAGRALIESGMSVRTVQVT------------CD-ADRRTLAGL
LTDVAG-SEDITGVVSFLAADEVPHP-----AHPALSRGMAHTVELVCSLTTADVGAPLWCVTRAAVTAPADPAPSPAQAAVWGFGRVAGLERSERWGGL
IDLPVHCDA---HVLRRFVAVLARAAGEDQVAVRPSAALGRRLESAPRTG----PAGAWRPHGTVLITGGTGVLGAHVARWLARSGAEHLVLLSRRGPQA
PGA------AVLDDELTALGVRVTVTACDVTDRAALAGVLASV-----PDLTAVVHLAGTVRFGNAIDADLDEYAGVFDAKVTGALHLDELLDHSSLEAF
VLFSSAAAVWGGVGQAGYAAANAMLDAVAQRRR-VRGLPATSIGWGTWGG-SLAP--EDEERLSRIGLRPMRPEAAVTELRHVVGSAEPCAIADVDWETF
GPA------------------FTTGRP----SPLLGELPQ-LRNTS-----------GSMAM----TGDHAALRRRLAGVS----AADQARTLVDLVREH
AAELLGHAAIDPTVPFRQLGFDSLTAVELRTRLNAATGLRLPATLLFDHPSCRAVGDLLRSEL---------
>tr|H3SB85|H3SB85_9BACL Polyketide synthase OS=Paenibacillus dendritiformis C454 GN=PDENDC454_03854 PE=4 SV=1
----------------------DHFFHHKRWVVQDEVTVTPPTEETWLVHCDSHGTP-LLARLREEGVRVIEVFLHDGFTQIDQDTYRIG-NNADDFKEL
FLQLS--DLPIRKIVHVGAYRDDDPG-SVNDMYQEFEYGFFNVVHLVKGLVKADQPVQLILVACNAYRISGEERLLPHHATVLSLGKVIEQENPNISCRA
IDTDRDTD------VGQIIGQLFADHQMYLIGLRQGTSYVEEFDEAEIQPE---TANRIVHGGTYIITGGTSGIGIQNAKLFSEQANCNLILLSRKGFPD
ESLWEKEQIKEFKQ-MKKNGAALEFIACDVTNADDVQTMLEAVRTR-YKKINGIVHCAGVIEPSFMLRKEKESYLSVFAPKITGTWNLANLTRNDDLDFM
LLHSSNVTDAGEPGQSCYMAANAFLDAYTDYLN-AQGRHTYTVNWVAWKETGMAHKQGTNV---DTVTKAITNRDAVNALNQLLRSKPQRVVIGQFNEQV
DLVPLLKH----S-RNAVAPSFT--------AKIYKE---AYKRQIGDAAPI---LVEPAPLSPSGKEI--K-------L--TGKMEGIYTPVEKQIGKI
YCDILGYEEADIYEGFFEMGGDSILLTEMHDTIDKLYPNIVKIADLFEFDSIHSLSEYITPRIPHDEA----
>tr|L8P1R0|L8P1R0_STRVR Putative Modular polyketide synthase OS=Streptomyces viridochromogenes Tue57 GN=STVIR_8608 PE=4 SV=1
--------------------EHGRHLYEVAWTALPERRAE-PPGTVWAVHGDPSAVGAALRELDAAGIRVA-----------------------------
-------DEGADVVVRFWPRPPADAEPA-----AAAHESATTALAELQALIALEAPTRTVWVTRGAIAAADDPVQGFAQSVLWGLARGARAEHPGLGLTL
IDLDGDEPA--------LLSAVA-HDDEDELARRDGEFLAPRLVRARTAPS--APTVPVPADGTVLITGGLGAVGRQIARLLAGQGAGRLLLTSRQGPDD
PRA--ADVTAE----LTALGAEVEVAACDVTDPAAVADVLARTGAE--RPLRGVVHCAGVLADGVVAELTPERLAQVLRPKADGAAHLHRLTAGHPLDLF
LLVSSAAGVVGNAGQANYAAANAFLDQLAHHRR-ASGLPGTSVSFGAWAGEGLAAEHADLARMARLGHRALTPEQGRELTALSLRRDTPHLVAALDLPRL
RAAAP---------PG---ALWR---------TLLP-----------EPRPA--------------QAGSPALADRLARLP----EPERAARVLTLVREE
ASRALGLESVRPDQPLRDLGMDSVTAVDLRNRISARIGAKLPATLLFDHPTPARLTEHLLAG----------
>tr|W4DCD9|W4DCD9_9BACL Amino acid adenylation protein OS=Paenibacillus sp. FSL R7-277 GN=C173_20406 PE=4 SV=1
---------------------GEEQYYQLNWVEAEKAVPPRTWEGAVLVIVGDGCLSDAIMKELRGQRYVVTAQLGREYSKISAMEYLIRN-TAADFSAL
LAQMKD--MNLTAIVHLASLSEQGGMDSENDLTAGLQRGVCSFRNLHLALAEETADLDLYLIAERVNAIHSDPVINPVFAPMFALAKVMKYENFNTQCKC
IDIDSETE------AEVIANEIASAAMDSNVAYRKGIRYVERLETFQPLDM-ELKPTGIRPKGVYVITGGTGGLGLQVAHYLSVQNQVTLILINRSCFPD
KKEWAADKVKSLQQ-VEGRGSQVRCYQADVSCPEDMISVLDEVRET-YGSIHGVIHSAGIGTGVSIQEQEEEDFLRTLAPKVQGTWLLDRLTQQDKLDFM
VLFTSPVTLIGGVGLSGYTCSNSFLDSFVHYRN-TGGKRTIAMSWAPWEFTVMGERFNPQ----KQLFQVISSERVREAFHDILNHDVQESIGGLNYQGE
-----------------LLPYYKEF-----SFRLSDSIIERIKGGLEQ--ASSYQ--------------------RVVEVRYKGEKVPP-HGHSESLGQI
IGGVLGMEKLDLESNFFELGGDSIIAMKVIVQINQVFQTALKVTDLLRFPDLHAFTGFIAEQT---------
>tr|R4LYM8|R4LYM8_MYCTX Polyketide synthase OS=Mycobacterium tuberculosis str. Haarlem/NITR202 GN=I917_20485 PE=4 SV=1
-------------------RALEDWCHQLAWPIRPAVSADPPSTAAWLVVADNVTLATSWPVRPILGX------TAXRQXXL---------AAXSDPAAL
LDALR----GVDNVLYAPPVPGELL-----D-----IESAYQVFHATRRLXAAISPPKLFIMTRNAQPISEGDRANPGHAVLWGLGRSLALEHPEIWGGI
IDLDDSMPA--ELAVRHVLTAAHGTDGEDQVVYRSGARHVPRLQRRTLPGK----PVTLNADASQLVIGATGNIGPHLIRQLARMGAKTIVAMARKPGA-
--------LDELTQCLAATGTDLIAVAADATDPAAMQTLFDRFGTE-LPPLEGIYLAAFAGRPALLSEMTDDDVTTMFRPKLDALALLHRRSLKSPVRHF
VLFSSVSGLLGSRWLAHYTATSAFLDSFAGARR-TMGLPATVVDWGLWKSLADVQKD-ATQISAESGLQPMADEVAIGALPLVMNPDAAVVVVAADWPLL
AAAYRT------------------RG----ALRIV-------DDLL-PA-PE------DVG------KGXSEFRTSLRSC----PAEKRRDMLFDHVGAL
AATVMGMEPLDPSAGFFQLGMDSLMSVTLQRALSESLGEFLPASVVFDYPTVYSLTDYLATVLPE-------
>tr|A0A0F4ESU1|A0A0F4ESU1_9MYCO Polyketide synthase (Fragment) OS=Mycobacterium lepromatosis GN=ppsB PE=4 SV=1
-------------------TELDGWIYQLDWPARPLTSETWASNGSWLVVSDAGLSDE-LARLVVLAD------PASRVECL---------ADVSTLDDL
HKALR----GVDNVLYAPSVSTESVDP--VD-----PESGYRLFHAVRRLAAATSKPRLVVVTRNAQPVAVGERANPAHAVLWGFGRTLALEHPEIWGNI
IDLDASMPP--ELAARCILDEVAGQDREDQVVYRACLRRAPRLQRRTVSAVS---PVSSGQATTQLVIGATGNIGPHLIRQLAAMGATTIVAVSRSSSTR
--------LVELDKSLAATGTNLISVAADATDPAAMTALFDRFGVD-LPPLEGIYLAAFAGQPVLLSDMTDDDVAAMFRPKLDVASLLHRLSLKQPVKYF
VLFSSISGLIGSRWLAHYTATSTFLDILGYARR-LVGLPATVVAWGLWKSLADVQQD-ATQVSAESGLQPMTDDVAIGALPLVMNPEAPVVVAAANWPIL
AAAYRT------------------RG----VLRMV-------DDLL-PA-PG------EVP------IQESEFRKALRTC----QAERRHDMLFDHVSAL
AAKAMGMEALDPSAGFFQLGMDSLMSVTLQRALSDSLGEFLPASVVFDYPTVYSLTDYLATILPE-------
>tr|A0A0N1GBL0|A0A0N1GBL0_9ACTN FkbH like protein OS=Actinobacteria bacterium OK006 GN=OK006_9711 PE=4 SV=1
--------------------ENARHLYEVVWTAVPEQPDE-APGTEWAVVGDPSEVAGALRGLAAAGTHV---RSGTGGAD-------VNGAG--GVD--
--VRGT--GGVDVFVRFWPRPATDAEPSA----AAQE-LAAAALAELRALIALEAPARTVWVTRGAVGAVKDTVPGLAQSVLWGLARSARAEHPELGLTL
LDLDDSDPAD------ALLTAA-THAEEPELASRAGTLLAPRLVRARDRDATGGRPALAPTDGTVLITGGLGAVGRHIARLLAEHGVPRLLLTSRQGPDD
PR--AAEVAAEL----TGLGAEVEVAACDIADATAVAGLLGRIGE--ESPLRGVVHCAGVLADGVVAELTPERLAQVLRPKVDGAAHLHRLTVDARLDLF
LLVSSAAGVVGNAGQGNYAAANVYLDQLAHHRR-ALGLPGVSLSFGAWAGEGLAAAHADLDRMARLGHRALTSDQGRELVELALRQGAPHLVAALDLPRL
RETATTAA------------TTGVGGTAAVWRSL-------------------------LPAPRTGRSGGDGLADRLARLP----EAERAERVLALVREE
ISRALGLESVRPDQPLRELGMDSVTAVELRNRIGARIGAKLPATLLFDHPTAARLAAHLLSTA---------
>tr|A0A0M2JL38|A0A0M2JL38_9ACTN Polyketide synthase OS=Streptomyces mangrovisoli GN=WN71_15135 PE=4 SV=1
--------------------GSARHLYEVAWTAVTAT--A-PPPAEWAVVGDVPLVPG----LHAA-----------------------------GVR--
--TVAA--DGAGTVVRFWPDPACPPGRPA----AVRA-FAATALAEVQALVALRAPARTVWVTRGAVGAAGDAVPGLAQSVLWGLARSARAEHPDLGLTL
LDLDGADPDP------ASLVAL-GLPDESEIAVREGTPLAPRLIRARTPQPPAARHPVVPTDGTVLVTGGLGAVGLHIARLLAEHGARRLLLTSRQGGDD
PR--AADAIAEL----AALGAEAEVAACDVADAGALAALL----D--GVPLRGVVHCAGVLDDGVVTELTPQRLETVLRPKADGAAHLHRLTAGRPLELF
LLVSSAAGVAGSPGQGNYAAANVFLDQLAHHRR-AMGLPAVSVSFGAWAGEGLAAAHADLARMARLGHRALTPEQGRDLVDLSLRRARPHLVASLDLPRL
RESAT----------------------GPLWSAL-------------------------LPAARTGAEGGRGLADRLAALP----GPERAERVLTLVREE
ISRALGLASVRPDQPLRDLGMDSVTAVELRNRIGRRVGVKLPATLLFDHPTADRVTAHLLAGP---------
>tr|D0LN43|D0LN43_HALO1 Amino acid adenylation domain protein OS=Haliangium ochraceum (strain DSM 14365 / JCM 11303 / SMP-2) GN=Hoch_0798 PE=4 SV=1
----------------------DSWL-ANVWVPAAEPDA-PAHASRWLLVGDGDGLRDRLAESLSHGHTLV--AE-------------------------
-------GEPHDEIVWLEALDADRDG------PEAARVACVTLMERVQRLVQEEHTPRLWLVTRGACEAQGC-LVDPAHAAVFGFARSLAAEHAELRPGR
IDLDPGLAPV--AQAAELTRALLAGDDEDETALRGGARFVGRLQRRLPGQAPVPAHSGFSDNATWLISGGLGGLGLSLAEGLVSWGVRAVALLGRSGVRT
--QHQRQAIERM----RAAGARVRVLEADVSQQASLEAALATLH--DLPPLRGVVHVAGVIDDGMIAGQSAERLAAVFAPKVSGAWNLHRATAACELDHF
VIYSSGASLLGSPGQSSYAAANGFVDGLAWARR-SAGLPALSINWGAFSDVGLAAAEARGERLASKGLRNLTPEEGLRLVRSLLATDVVQVALPFDIARW
LESL----------PQ-----LA-------SSSRFAELVS-------SE------DVDA------G-PAVEDLAALLA----SSVSARRVALCEDYVRRQ
LAQVIGIDQLPLRRPLTEMGLDSLTGLELRNRLEAGVGKKLSATLAWSYPTIEALAGHLLEQL---------
>tr|W7YV94|W7YV94_9BACL Malonyl CoA-acyl carrier protein transacylase OS=Paenibacillus pini JCM 16418 GN=JCM16418_317 PE=4 SV=1
------------------------MHYQLGWVAAPKLESISIESQAVLILKSDLGWGKRISDFRDKGYPVIEVQLGSSTAFIHHGQHVDMQGCQEDFDQL
FTDLKGR-YHLEHIVYVGANAPLET---KGEQGEASTD-EIYLFRAVKALQSDERSLKLSLLTNQAFVVDDKESIHAERAVMTGLGKAIAKENPDWLCKA
MDTDDDAD------VEAVLEELLHVDKEYQIAIRQGQRYALELQPMDPSRL-KDDPLVIREGGIYIITGGLGDIGLEMAKYLASRQNVNLALISRTAFPN
REQWPQSRIEEVMA-IEALGSKVYCYAGDVSDVVAMEQIITAIRDQSNAGICGVIHAAGVPGNQMLNEQQETEFKRVLSPKVEGTMVLDQLLHGEALDFF
ILCSSLATFFPAPGQGDYIAANTYLDAYAAMKS-KQGTRTITINWSTWKERGMAVKAGFA---VDTLMRALRTEEAMSQFDLIVNKDVSQVLIGLDFDSR
LIRLLPEMPY-RMHDSIIYEELGTK--------SRANITAQ-AGML-CSTTAAGSSMGTNSRASNGV-------ARVVQLSG--RENGIYSDAERITAQV
WAETLGIYDMNVYHNYYEMGGDSVLGIRIVNTLNKQLQIRLHPGDLLTRLTVEQFGAFLESMI---------
>tr|X2GUJ4|X2GUJ4_9BACI Uncharacterized protein OS=Lysinibacillus varians GN=T479_05860 PE=4 SV=1
-------------------SSANKLYYHTDWVQTDAIRKLLPVNKQYLLIADEAIAAASLKENMEKHHNTICVLHGDEFLKKNTHDYTINQDNKEEWSKL
FADVCKSGKKNLNIIYCTTKDSVQNL----ANNKVNYRAIKALHYLVQVMNEETQGSKIKIVTKDVQKLRHEKKLNLSGSMVWGLAKVMSIEYPEIFGGI
IDTDEITFYEN----SDFIHEVL-GDSVQEVCFRENERYVGRLITHADYKLEKNKKIVLKEEASYLITGGTGALGLAYAEQLVNAGAKNLILISRREPSE
H---AKVAIQKLI----DKAVQVKIVHADVCNDESLIKALDDIQ-FTMPPIRGVVHAAGVLNDKMLIDLNWEDFEKVMNPKVVGTLNVFNAIDKETLDFF
MMLSSITSVIGNMGQGNYAAANHFMNSFATYMN-MNKLPGYTFCWGPWNESGMAADNDISSTMARMGMKTFSKGQGQSIINDFMDQPYELLIADIEWNTL
VKSLETAAG---------------------KTEFLSK-------LV-SEKDLHV---DIV---QD---EKDNFLETLMSL----SGEGQNEILIEKLQSI
CGKIMGFDVLSIDKAFQEQGADSLMIFSMRTAINKLLGIDVNVSVFFNYPTIVKLSDYLLSEV---------
>tr|A0A0P9V408|A0A0P9V408_PSEA0 Non-ribosomal peptide synthetase/polyketide synthetase (Fragment) OS=Pseudomonas amygdali pv. mori GN=ALO63_04931 PE=4 SV=1
------------------RELMADWFYQRQWQRVRRLGTQPIERRDRLVVCSHERVDAALLGCLQVYRHVIEVQAGNGYQQLGPNLYELDPLDPLAFSRL
IAELDQSGQAATEWLHALPLSVGGVV-NEQSLAAAQWACLDTVSAFLQAWGQRKTALRLWLLSWQACPVNGQ-VMRPELAALAGITEVAPQEYP-IRCHW
LDLPTAQWGTQARQLATLLAEPT--SLPRRMAIRDGYLWQPQLQPSSLALPT-VVSNLLPVNGTFLVLGGTGGIGRTLCEHLLQSSQRRVVLLSRRGECP
---------QELG----DYAARIDSVQADIADLARWPKVLEQLRER-YGHFDGVIHAAGTGAGSLIRQRDAHLLSEAMASKTRGMLAVEALIEQMTPGFV
LYCSSMSALFGGAGHLDYAAASAVLDGFAHYRPNENGCVRLGINWDIWRETGMAAASGIGDEAHQRHAVGMSAQEGCQVFDAAMTAQLPQLLISTDLNTA
-------------------------------RQFYPA-------RHSGA---GLTL-----------VDT-------------APAVAAETGLPERLHGC
LCKWLGVSALDPDDSLYELGADSLTLLDLIDELQAATGVVFQLSQFSHKVSLREVLALVQSA----------
>tr|A0A0M8QD86|A0A0M8QD86_9ACTN Polyketide synthase (Fragment) OS=Streptomyces caelestis GN=ADK41_36040 PE=4 SV=1
-----------------PADPADAWTHRVTWRALPDPAP-ARLSGSWLLVVPEAAVGAPLAEATGHGADVLAVPDGTD------------------RSGL
AARVP-SG--MTGVLSLLA----------------PVTGPGTTLQLVQALGDAGADAPLWCVTTGAVAVDDSGPDRPEQAQVWGLGRVAALEHPRRWGGL
VDLPEQLDDT---AMRRLCALLRARCAEDQVAVRADGLYGRRLVREPAAGGAEGGARAWTVRGTVLVTGGTGGLGAQVARRLARGGADHLVLTSRRGARA
PG--AAELVREL----TAAGTRTTVAACDVADRPALADLLARLAA-DGDTVRAVFHAAGVTSATRIEDCTPALLTEETAAKVRGTVHLDALLG-DGLEAF
VLFSSVSAVWGSAGQATYAAANAFLDAAAARRR-AQGRAATCVAWGPWAGPGMAQGET-GAQLRRLGLVPMAPEAALDALWRALERDDSGAVADMDWARF
APTFRS------------------G----RESALFGDLLEA---TTEPAN---------GPVAAAGRTDAVRWRERLAVL----PGAERQRLLTELVRTE
AAAVLGHDAVDAGRPFHDLGFDSLTAVELRNRLAAATGLTLPASTVFDHPTATVLGHHLLTEL---------
>tr|A0A0K6KXS3|A0A0K6KXS3_BACAM Polyketide synthase PksL OS=Bacillus amyloliquefaciens GN=pksL_2 PE=4 SV=1
-------------------SNHPLFYYKPEWTESFIPSKKSPLTGLLLIFAENERQIQELTGLFK-DCTLLFVIRGKEFAVLHDDTICMNHVKKHDYLKL
FRYIHDHYQLPEKILHLWSDSQADM--SKGDIQKQLENGLFSLLYITQALIELKW-KKIIKLTHIFQT--ENKEQLPLHHALGGLVKTVHQEHPNFHYQI
INITQSEGAGAAAIADIYQRECDEKDIHFEVRYENGRRFTKSYNKAGSF----DLTQPLKHHGNYLITGGLGGLGYILAKHLSEKWKANLILTGRSDLT-
--EEQEKKIEYL----RSSGSTVEYIRSDVSKQSDAERIFAFAKEQ-FGTLHGVFHSAGVLRDSFILRKTKEEIDQVTGSKVYGTLWLAEEIKKMKVELL
VLFSSTSAVFGSAGQCDYAFANAFLDQYAAVMTAESAERVVSVNWPLWTSGGMNIDDEVSYMKQELGLDPLDDSDGIQALENSLCQSSEQLIA-LKGRKE
K------------------------------------IEDVLKRA--GTI----------SFHSEQQEDA-D-------L----QNDELRQNIISYLKNI
MSEELKLSLIDEKQYLEKYGIDSVMIMRLTKKLEQSIG-RLSKTLFFEYHSISQLAEYFLSHHS--------
>tr|A0A0N8SRJ9|A0A0N8SRJ9_PSESX Syringopeptin synthetase C OS=Pseudomonas syringae pv. solidagae GN=ALO46_04004 PE=4 SV=1
-------------------TEPLDWCQAPAWRPALPPRSDSPLQGPWLVVMRGVAADNSM--LFSLPDSVCIADAGDS----GTAVATIARGDAQAYEQL
FNTLAAQDALPSQIIYMAGQAQPTHGE------HAAIRLFTDLMSLVQAYIPHANTTVLSLVTEGACQVDDDEPVNSCVATLSGVVRTLAWELPQIQCRH
FDLPLANAAENETLLLQALQHIDPSPLASTLALRKQTFHEPCLRALQVSPP----SQPFEEGGTYVVTGGLGGMGLALASHLAAKAAVTLVLMSRFATV-
-TDEVGQALQAL----EQQGARIQHMAVDCADREAFTAALHQVRLQ-HGRISGAIHAAGVQASGLIQLSQATAWAQVMGSKVVGTDVLIEVLRQEPVDFI
FLCSSLASVLGGLGQADYAAANAYLDARAQACR-QEGIPVVSLNWDAWAQAGMRVAYDRPEQAPIDDVRGLTNAEGCQLFELALAQNTAQVIVSKAQD--
-LQ-----------------------------QLIE----QLQRG--GA-------------TSAGRAT--PL---FD---SGAERVAPRNAVEQEVAQL
WQELLGGDMPGVLDNFFDLGGHSLLGSQLISRIRSRFQQCLTLAEFLDEPTIERIARSLGSGA---------
>tr|A0A0M8QD86|A0A0M8QD86_9ACTN Polyketide synthase (Fragment) OS=Streptomyces caelestis GN=ADK41_36040 PE=4 SV=1
-----------------RERRVDSWRHRVAWRPLDVPPA-AAPPGRWLAVCPSQEAAADVVGLAALGLDLTVVTPGQS------------------RAAL
AAALTEAGRPLAGVLSLLADEQHPHPE-----HPSLPGALALTLALVQALGDAGTDAPLWCVTRGTAVIEAERPGAAAHAAVAGLGRCAALEHPDRWGGS
IDLPQKPDE---RTLRRLCAVLASVTDEDQVAVRATGVHGRRLLPAPAHGKTP-VPDRAFGHGTVLVTGGTGGVGSHVARWLAAHGADHLLLVGRRGPRA
PGA------DALRAELEESGTSVTVAACDVTDPRQVTELLGALPP--DRPLTAVVHAAGVLDDGVLDALTPARLSVSLRAKVTAADVLHRATADLDLSAF
VVFTSLMGVVGNAGQANYAAANAALESFVASRR-ADGLPGTALAWGAWAAEGMLADG-VAGRLRDRGLSSMDPTVAVTAIGRALTQDDALVVADADWRRF
AGTAGPR-----------------------AATLLSELTGRDDD-----------RVESRPDTSDGSKSEGALRGQLAA----VPVAERARFVTDLVRTH
AAAVLRHDAVHPERAFTELGFDSLTAVELRNRLAAATDVRLPATVLFDRPTPAVLAEHLLCEL---------
>tr|B8I8J7|B8I8J7_CLOCE Beta-ketoacyl synthase OS=Clostridium cellulolyticum (strain ATCC 35319 / DSM 5812 / JCM 6584 / H10) GN=Ccel_0858 PE=4 SV=1
------------------------LYFKYIWKNSEIAEKAISELGSILLFDRNGELASLLGVANKEGEPCVLVMPGAEFSEQKGNIFTINPEKPDDYKKL
LQTLKARQMLPKNIIYKWARTGVGFD--QADMCSCLKDGIYSVLHLTKALAEQKDKVLLLFVHSPA----G-KGGHPLYSGMGAFFKTLRLENPGFVYKS
VEMEQDNK---DDVAQRLINELTLGVGALEVRYEGKQRLVKAMEEISGQIT--DGKIAIKEGGVYLITGGAGGLGLIMAERLAQRAKIKLVLTGRSDLK-
--QDKLLKLKEL----EALGSEILYIKADISMKDHAQRLIDEVKAN-FGKIDGVIHSAGIYKSGFVIKKTPEEMETVFAPKIFGAAFIDEVTKDEDMDFF
IMFSSISAVAGDLGLSDYAYGNGFMDDFAELRETMRKGRTLSINWPLWEYGGMQISKESQRFFDRTGLNMLPTRQGLEFFDSVTSMTNIQCLVA------
---------------------YGDR------EKV----KKFIEASFR--D----------T-RNSGKGQA---------V--SMDPKVLLEKTEEFLKKI
IADEIDVDQVDSDVSFEEYGIDSILIHNFNFKIEKHIG-PTSKTLLFEYKYLKDLTEYFVKNHA--------
>tr|F1T732|F1T732_9FIRM 6-deoxyerythronolide-B synthase OS=[Clostridium] papyrosolvens DSM 2782 GN=Cpap_3712 PE=4 SV=1
--------------------------------------MDYSEKQRLLVFSNID-KSNF------EGDAKELVYVVSDSKKAQMDEYSVQPELLEDSFYI
FNKLEQMEYVPDVILVALNDS---------EEIRKTKDYVLSTANLAKCLIQKNKG---KLLFSSM----G-NESGMYSEGLTAFFKTLHIEYENLYFRN
IICYEQTT---SDFVSVLNKEINYFSSEYKVTYRKLQRTVQTYTDYQ--PE--TQIPYLKENGTYILLGGFGEIGKVIAKHLTEQANVNLILCGRKPEN-
--DKVREFINPL----NQGSTRVIYKSVDISIKEQLQGLIDNVINE-FGYITGIFNMTGYIEPGFLESKDNGFLRNGVKLKVDATVFLDEITKDINLDFF
VNFSSVSALVGDFGLSEYVYANCFFDEFISKREKLRCGNSISINWPYWQDGGLRMVEDASRFSLTTGLSPLLNKDAITAFDSIMKSNVSQCCVL------
---------------------FGKD------KKM----NDYLESKLT--L----------P-TILQKNIN---------L--SLDNSSVKTIVEQYLTKV
IAKELKNDDIDLEDGFQSMGIDSILIHKLNRVLSADFS-GVSSTIFFDCKNIDEMVSYFVQTYS--------
>tr|I2NBN3|I2NBN3_9ACTN Type I polyketide synthase OS=Streptomyces tsukubaensis NRRL18488 GN=STSU_00540 PE=4 SV=1
--------------------SVDDWRYRITWQPSGLHPDSPVLSGTWLLVGHDPQ-APAIAALTRHGADVLTVAPGD-----------LDPAV-------
LA-------NAAGVVSLLALDETPDTRH-----PWVASGTAATLDLVHALHRAASTTPVWLLTRGAVRTTADATTSPAQSAVWGLGRAVGLEHPGLWGGL
ADLPAEFTA---ETGTRLAAVLADPGHEDQIALRGNAVLVRRLSRALPAPA---PRRPWSPRGTVLLTGGTGSVGTHIATWLARQGTRRLVLTSRSGPSA
PGA------AALAAAAATSGTDTDIISCDLNTPDQVSRLVAWTQ-ASGPALSTVFHSATVATLARVEDTDHDNLAQALGAKAAGAVHLDQATTGLDLDEF
VLFSSISATWGSNDHGAYAAGNSFLDGFAEARR-SRGLPATSIAWGVWNTQDWDQAPGTPGRLRRQGMNFMDTDRALTALGHILTHDETFIVADITWDTF
AP------------------VFRAAR----PRPLLDTIPEA---REEPPTPT-------GPAGQGGQAEHGQYATLLAR----MPHTERHRTLTELVRSH
AAAVLGHTDVPAERPFRDIGFDSLTAVELRNRLNTTTGTRLPATAVFDHPDPTTLAREILTRL---------
>tr|A0A0N7JEP4|A0A0N7JEP4_9SPHI Uncharacterized protein OS=Pedobacter sp. PACM 27299 GN=AQ505_08705 PE=4 SV=1
---------------------TSGLQYKLLWNEAGPLSELGHQPGNWIVVGERTEMLESIISALQAKYPTFWMATGSGERKIKP--TVVLPDQKEEWHSA
LARIKDRESRADKILFLDPVDK-------EQLFSRNNRGLEQLIPLTQAIHSTAMLTSLWVVSHDAHLVAADQSINMASAFTWGFAKTLFLEHPELRGGL
IDLSESDELNS--RTADLIKKILTPEFERAVVIRSGRPYIQQLVSAPLDAA---KPKSFRGDGVFIITGGLGGLGLKCAEWACSKGARKLILLSRRRLPD
RSEWAEAIVQQLMK-LEDKGVALEVLSLDVSSPEALSALFDRLDRD-KVPVRGVLHAAGLNWFSKILDLDQQRFFNTLKIKGAASWELHKNTTNRDLDCF
LLFSSVSAVWGSVDLSHYTAANQFMDALSIYRG-QLGLPSLSIDWGPWAEVGMSSQSAEKTLLEKLGFALMAPETALKAMDEALSTSENVLIADVKWNNF
RPFID----------------FC------------------LQPSL-------FANVPLLPE-INRKTEERKIHARLKE----SSPEEAMVLIEQIIRAE
LRTVTSTDSIDADQRFNFMGLDSLMAISYVAKLENYFQLKLPSTLTYNYPTIRLLREHLFELL---------
>tr|A0A0D0HC25|A0A0D0HC25_9BURK KY49.ctg7180000000020_quiver, whole genome shotgun sequence OS=Burkholderia sp. MSHR3999 GN=KY49_5839 PE=4 SV=1
---------------------AASTLHAPRWQPVDLPSDADEAGRPWLIVGDAAAAGDAFAAALARGARVERLDLAGA-----------DAAGLAALERR
LLDYAAAHAEPFGLIHVHPAGSPGAA--------AADL---AVVRFVAGLSA-GRLHRALLVTRGAQPVAGEA-PGASGAALWGLGATLQAEAPQQAVTL
VDLDAGRCDA--ADADAVLRAADAARWPDHLALRAGRCHQRALGPVHAL-----GPMAIAGDGTYLVTGGLGGVGRRVVEFLHARGAGRIVVLGRGVPAE
PPA----WLAALDA----RRAALEWVACDVTDAARVAAVVGALARE--ARIRGIVHAAGVLDDARLVEQDAARLQRVAAPKLDGARHLLDALPAASLDFV
WLFSSITALFGGAGQANYAAANAALDSFAHALR-ARGVPATAINWGPWRDTGMLARVAPDATYARLHADPLDPADAARWFDALLAIDDAQCSV-VHWRLD
AL---AQA--------R------------RLPVLLRPLAAKVA------------KAEGGAAA-TASADAGSYLQRLAG---A-LPAERAALARRFVAEQ
IAAITGIDAIAPAAPLSGLGMDSLMSVALSDALADCLGIAYSATLLFDHPTLDALAAHVLAGN---------
>tr|Q0B303|Q0B303_BURCM Beta-ketoacyl synthase OS=Burkholderia ambifaria (strain ATCC BAA-244 / AMMD) GN=Bamb_5925 PE=4 SV=1
---------------------SASPLHALRWRRVDPPS-VDEAGRSWLVVSAAGASGGAFAAALARGARVERLDPRDH-----------DAAGLAAFARS
LADYAAARAEPFGLIHLHAD-----A--------AVDL---AVVRFLAGLPA-GCLHRALLVTQGAQAVAGEL-PDLSATVLWGLGATLQAEAPQQAVTL
VDLEAGLDAL--VGIETVLNAADAPAWPDHLALRAGRWHQRVLAPATAR-----GPLTISGDGSYLVTGGLGGLGRRVVEFLHARGAGRIVVLGRTLPAE
PPA----WLAALQA----ERAVVELVACDLSDAARVASVPGTLGRE--LPLRGIVHAAGVLDDARLIDQDAARLRRVAAPKLDGARHLLDALAGASLDFV
WLFSSITALHGGAGQANYAAANAALDGYAHTLR-ARGVPATAINWGPWRDTGMLARVAPEATYARLHADPLEPAEAARWFDALLATDGAQLCV-VHWRLD
AL---ARV--------P------------GLPALLRDLVTAAT------------SVAT-PAT-AGQAGPASYRQRLAD---A-LPAERAALARRLVAEQ
IALVTGIATIEPAAPLSILGMDSLMSVALSDALAHCLGIAASATLLFDHPTLDALALHVLAAN---------
>tr|M1MCR4|M1MCR4_9CLOT Polyketide synthase PksN OS=Clostridium saccharoperbutylacetonicum N1-4(HMT) GN=pksN PE=4 SV=1
------------------------QMYHYVWKKNNKKMMGRSKVGSLLIFDNDKILAQEFR----YANDITYVLSGNKFRECQNGVYEIATSDEESYFKL
FDELRRRGKLPNQIVYKWTYIGNST-------GENVRTAFYAMLHIARALVKLKDKVKLLYLYQDENN-----HEAVMNDALSGFVKTLQMEHPNLYFRI
IKIKGIQYS----IKDLIESELQV-DDTNTVYYQDNTRYMEQLIRDDVKHL--DSKVPFKERGTYLITGGMGEIGLSLARYLASNFRANLILTGRSVLDA
K---KQENLEELR----MLGANVSYISVDMSKRKDVMRMKEQIKDQ-FTTIQGIISCAGVVRDSFIINKTMLQIEEVLRAKIDATIIMDQVMKDEKLDFF
LLFSSISH-LGNIGQADYAVANSFLNSFASYRKKERYGKTVSINWPIWEQGGMHMETAVERQKERTGVYPLPTQVGLEAIRNSLMQENDTVLIYGEGKKL
-------------------------------QKFVSH----LNSRE-----------DQM-----GE---KEI-----EVKSEMNQKELIESVMTFLQNT
AEELIKVNDLNIDKDLSECGFDSISNTDYTNKINDYYGLEVMPTIFFEMPTVRALCNYLIKNYS--------
>tr|A0A0C1ZNA2|A0A0C1ZNA2_PSEFL Thioester reductase OS=Pseudomonas fluorescens GN=NX10_20985 PE=4 SV=1
-----------------ERQPLADWFHQRQWVRTRRLSATAAGSREVLILCSDAPESTLLASLNAVYRRVIQVRTGNGFKRLSADSFELDPLDTEALSRL
LTEVAEPALGELDWLHALPLAVSGAV-NEQSLDLAQWACLDTVSALMQAWGQTTTRLRLWLMSWQACPVDGE-VQRPELAALAGITEVVPQEYP-VRCHW
LDWPSSRLGAHAGELAALCVD--PVSLPRRMAVRDGYLWQPRLMPQPLTGPA-TTSGLLPEDGTFLVLGGSGGIGRTLCEHLLQAPARRVVLLSRQGQLP
---------VSLA----AYALRIDCIKADIADLPRWPQVLDQLAVR-YGRVSGVIHAAGVGAGSLIRHRDARQMAEAMAAKTRGMLAVEALIEHLTPDFV
LYCSSMSALFGGAGHLDYAAASGVLDGFTHYRPNATACLRLEINWDIWRDIGMATTSYSAAHLE-HLTVGLSAEEGCRVFDLAMAMQLPQLLISTTG---
-----I-----------------------DTARRFYPVRH-------------A-------------VAAV-----VE--------APKGVDLSTRLREC
LCKWLGVAELEDDDSLYDLGADSLTLLDLIDELQAATGEVFQLSQFSHKVSLSEVLGLVSTAT---------
>tr|A0A0N1NA15|A0A0N1NA15_9ACTN Amino acid adenylation domain protein OS=Actinobacteria bacterium OK006 GN=OK006_8448 PE=4 SV=1
-----------------RRLPRENWLHQPHWVRLRRATVADAGRASAVVVVAENTPRTALAPFEAVASHVIRVHPAGAFARRGPDAYDADPADPASLREL
LNALGVPATVDTEWVHALPLDVTGPV-GPGTLQHARHTCIDSTAALAQALT--NGSPRVWWLSYGARPVTET-VDRPELALLAGPVEVAHQESA-LNGHW
LDLPDGDLTRWAGHVASVVAD--GPALPRQLALRQDYWWRPGTIPVPEPKGT-QSLVPSGADTVHLVLGGTGGIGRAIAAWLLEHTRGRVLLLSRNPRLP
---------EELN----RWANRIGLVPADLATMPVHE-VAPAVADH-TSRLDGVIHAAGLGHGGLLVRRDATAMRDAAAVRERGALVVEHLIGAFRPEIA
VYCSSMSALLGGVGQSDYAASASLLDGFAHHRAPGTTTVRIGIDWDIWSETGMATRVLNTRHQA-HLAVGLTVEEGKAVFAHALALQLPQLLVSTTD---
-----I-----------------------ELSRAFYAPTE-------------I-------------ADRSSCSGPVH--------PTDGGERADAMARV
IQDLLGVDELAPEDSLYDLGADSLTLISLIAQIEDDYGVEFDLASFSHRVSLAEILKHIEAAL---------
>tr|A0A0C1ZX19|A0A0C1ZX19_PSEFL Thioester reductase OS=Pseudomonas fluorescens GN=QS95_21220 PE=4 SV=1
------------------RQPLADWFHQRQWVRTRRLSATTAESREVLILCSHEAPESTLASLNTVYRRVIQVRAGNGFKRLSPDRFELDPLDIEALNRL
LAEVAEPELGELDWLHALPLAVSGAV-NEQSLDLAQWACLDTVSALMQVWGQTPTRLRLWLMSWQACPVDGE-VQRPELAALAGITEVVPQEYP-VRCHW
LDWPSSRLET---QAGELAALLADPSLPRRMAVRDGYLWQPRLLPQPLTGPA-TTSGLLPEDGTFLVLGGSGGIGRTLCEHLLQAPARRVVLLSRQGQLP
---------ASL----TAYASRIDCIKADIADLPRWPQVLDQLAVR-YGRLSGVIHAAGVGAGSLIRLRNARQMAEAMAAKTRGMLAVEALIEHLTPGFV
LYCSSMSALFGGAGHLDYAAASGVLDGFTHYCPNPDTCLRLGINWDIWRDIGMATTSNGGDAAHEHLTVGLSAEEGCRVFDLAMATQLPQLLISTTG---
-----I-----------------------ETARRF--------------YPVR-----------HGAVAA--------------AVEAPGVDLSARLREC
LCKWLGVAELEDDDSLYDLGADSLTLLDLIDELQAATGEVFQLSQFSHKVSLSEVLGLV-------------
>tr|M2NQY9|M2NQY9_9PSEU Malonyl CoA-acyl carrier protein transacylase OS=Amycolatopsis azurea DSM 43854 GN=C791_5749 PE=4 SV=1
------------------PVPMTDLLFETVWRQADLPPEK-PGTRHWVVLHENAPWLTALRDRLESGDE-----------------LTIAPLG--DRAAL
AEILRSRD--TAGVLACVPASDPM---GS-------ARTVATLSGVVAELAEAATAPRLWLVSAGASAIEPGERGDPGQAWPRGLVRVLAFEHPELRASQ
VDFDAEPDP-ARLWIARLVAEIRADAPDDEIAWREGVRYTRVLARPELGEP---CRETVVREGAYVITGGLGGLGLFAADWLAKRGATRLVLSGRRGASP
E----------LEPTLADLGADVRVVAGDIAEPGTAEALVAAAT-EGGVPLRGVLHAAGVLSDGAVASVEVDAAEAVWRAKALGAWRLHEATAGHDLDWW
LTYSSAAALFGSPGQAAYATANAWVDALVAWRR-AAGLPAATIGWGAWGEAGAAVGNR------NPVLEPLGTEEALTAMDAVLKRDRGATIARVDAGT-
-----------------VLALFPGL----AARPFFELLV--------PKE-------NAGPSTWDG---LDALRAV--------LPEAAREMLADYLAGL
VAGMLGLDGIDRHTSLTRLGLDSLTAMRAKGVVERDFGLPLPIPLLLRGASLAEIADHLAGQA---------
>tr|A0A0M4LMR7|A0A0M4LMR7_PSESX Thioester reductase OS=Pseudomonas syringae UMAF0158 GN=PSYRMG_24725 PE=4 SV=1
-----------------ERQPLADWFYQRQWQRVNRLRINPTEGREVLVVCSHERLDTTLGSLQSVYRHVIEVQAGNGYQQLGLNRYELDPLDPVALGRL
ISALDQSGQTASEWLHALPLSVGGAV-DEQSLAAAQWACLDTLSALLQAWGQNKTALRLWLLSWRACPVNGQ-VMRPELAALAGITEVAPQEYP-IRCHW
LDLPTAQLSTQAPHLAALLAEPV--LLPRRMAIRDGYLWQPQLLASPLAAPT-AASNLLPANGTFLVLGGTGGIGRTLCEHLLRSSQRRVVLLSRGGGCP
---------KELD----AYASRIDSIAADIADLARWPTVLEHLRER-YGHFDGVIHAAGTGAGSLIRQRDAQVLSEAMASKTRGMLAVEALIEQMTPGFV
LYCSSMSALFGGAGHLDYAAASAVLDGFTHYRAHANGCVRLGINWDIWRDVGMAAASGVGDDAHQRLAVGMSAQEGCRVFDAAMTAQLPQLLISTDPAT-
-------------------------------ARQFYPVRHSAGSTL---------------------ADTAP---VL---T---ADTAAPDCLPEHLHDC
LCKWLGVSALQPDASLYELGADSLTLLDLIDELQAATGVVFQLSQFSHKVSLAEVLALVRA-----------
>tr|A0A0C2DDB4|A0A0C2DDB4_9DELT Malonyl CoA-acyl carrier protein transacylase OS=Enhygromyxa salina GN=DB30_02711 PE=4 SV=1
-------------------------------------------PEELLLISPDDGLARGLERAAARLTACPLRKSAARSTRLEADRFELDLTCEGDVDAL
FEDLARVRRLPDTVVL----DARGED-------NVGADHLHSLLYLCRALVRAKPSVRVLHLRNHARGL-----ADGVHAMVGGFARTLARENPQIQLVA
IACDLDTED------AVLRAELGHYAAMAEVEHRGGRRLVREMVEVPTPRAYTETQSMIREHGRYLISGGMGALGLAVAQHLARDHAASLVLLGRSPMTA
---DIRARLESL----SAAGGDAIYMQADVSERAQVEAVFAELGRR-DLQLDGIIHAAGLIEDAFVLRKRPESLDRVLAPKVAGALNLDAASTDHPLGLF
VLFSSVASLMPNQGQCDYAAANAFLDHFAAQRELERRGATLAINWPLWAKGGITVAPEERHLWTEFGMHPMATAVGVELFARLTCDAGSPHYAPIEGDRD
K------------------------------------IEAHLRIAA----ASAVVEVDE---TS-------------------TSSSSLSGRIDRMLAAL
VDREAAPRHGRGAPTLSELGLDSLGMIRFADRLSSELGLEIKPSIFFEYATVPSLVAYLAQRKP--------
>tr|S5TP53|S5TP53_PSEFL NRPS (Fragment) OS=Pseudomonas fluorescens GN=nrps PE=4 SV=1
------------------RQPLADWFYQRQWVRVRRLNTVTERRETLVICSNETLDTTLLESLNTVYQRVIHLRAGNGFKRLGTDRFELDPLDAQALSRL
LDELAEPALGELDWLHALPLSVTGAV-NEQSLAAAQWAGLDTVSALMQAWGQAATTLRLWLMSWQACPVDGEV-IRPELAALAGITEVVPQEYP-VRCHW
LDWPTFRM--GAQELATLLADPA--SLPRRMAIRDGYLWQPRLIASPLPASV-PMANRLPMDGMFLVLGGTGGIGRTLAEHLLQAPQRRIVVLSRRG---
----------ELPAALAAYGSRIDCVQADIADLANWPAVLEQL-ARCYGRFAGVIHAAGVGAGSLIRQRDARQLGEAMAAKTRGMLAVEALISTMNPGFV
LYCSSMSALFGGAGHMDYAAASALLDGFAHYRPSASDCVRLGINWDIWRDIGMATTSGTGDAAHQEHLVGMSAEEGCRVFDLAMTTQLPQLLI-------
--------------------------------------------------------------STTGIDTARRFYPVRHGAVIAPVNVPEVLDLHSHLHES
LCKWLGVTRLDDDDSLYELGADSLTLLDLIDELQAATGVVFQLSQFSHKVSLQEILALVDA-----------
>tr|I9B3E8|I9B3E8_9FIRM Thioester reductase domain protein OS=Pelosinus fermentans B4 GN=FB4_2641 PE=4 SV=1
---------------------FEMMTFEETWQEQALANRATVKIRTLVCFLSNLVVAEAVQSF-DPETKILFISQSPSSPASSHVIHHISRKDRSTYEQV
FQSIREDYGDVDGVLYLWPLEDVTCI-----------EDYSAIVYLLQSIAAVK--LKAKRVLLGAQFEMGL--ERCYLDSWIGFERSLGLVLPNTQVAV
MYQESSGQDFMKDWLTKLWSELQT-EKIQSVFYQEGKRHVYQIQETSLETG----SSLLQAGGTYLITGGCGGLGFLFARHFANTHAVNLILTGRSALDE
---EKQAKVRELE----ALGSHALYLQADSCDVSSMKIALGQAKEK-FGEIHGVIHAAGLAGRQSIFEKDMTGFMRIIEPKIKGTLVLDEVLQEEALHFI
CYFSSSSAILGDFGSCDYAIGNRFQMAYAHYRQEKQGGKSLVINWPLWKDGGMEVGEESKFYLKSSGQRFLEAEEGTLIFDSILSQNKTQLLVGQ-PSRI
K-------------------------------RFLGL-T---QD----DVS-----LSLLSLDSSAKGRRPEMK-----------GLNLEECVEWDLKEY
ISQLLKINKLDKEDNLADFGFDSISLAQFAALLRSHFGIEVTATLFFGYSTIKKLTQYFVTDH---------
>tr|I9NV79|I9NV79_9FIRM Thioester reductase domain protein OS=Pelosinus fermentans JBW45 GN=JBW_00862 PE=4 SV=1
---------------------FEMMTFEETWQEQALSNRGPVKIRTLVCFLSNVKAAEEIQTL-DPQTRILFISQHPNHTASSHTIYPISRKDPSTYEQA
FQSIREDYGEIDGMLYLWTIEDATCI-----------EDYSVIVYLLQSIAAVK--LKAGRVLLGAQFETGL--ERCYLDSWVGFERSLGLVLPNTQVAV
TYQKSSGPDTMEDWLTKLWSELQT-EKLQSVFYQEGKRYVYQIQETFLETG----SSLLQAGGTYLITGGCGGLGFLFARHFAKTHAVNLILTGRSALDA
---KKQAKIHELE----ALGSHALYLQADSCDVSSMRSALAQAKAK-YGEIHGVIHAAGLAGSQSLFEKDLAGFKKIIEPKIKGTLVLDEVLQEVALHFM
CYFSSSSAILGDFGSCDYAIGNRFQMAYAHYRQEKQGGKSLVINWPLWKDGGMGVGEESKLYLKSSGQRFLEAEEGTVMFDCILSQSTIQLLVGQ-PSRI
K-------------------------------RFLGL-T---HD----DVS-----LSLLSLNSPSRGRRPEMK-----------GLNLEQCVEWDLKEY
ISQLLKINKLDKEENLADFGFDSISLTQLAALLRSHYGIEVTATLFFGYSTIEKLTQYFVTDH---------
>tr|Q9Z5F4|Q9Z5F4_MYXXA Ta1 (Fragment) OS=Myxococcus xanthus GN=ta1 PE=4 SV=1
------------------HPDAGVPLFVPTWQPWSEGASNASALRHLVVLCEPLALGAEASALASTADRRIEVVRTSPSARLD-ARFM--AHASAVFERV
KALLSERLTAPV---------------------------------------------TLQVL------V-PEERDALALSGLGSLLRSVSQENPLVRGQL
IRVQGSVSA--SALVDVLVK-SARAGDVTDSRYHAGQLSRCEWREARVAKG--DASRFWREDGVYVISGGTGALARLFVAEIGKRATRATVILVARASSA
EA--------VD----GGNGLRVRHLPVDVTQPNDVNAFVATVLRE-HGRIDGVIHAAGIRRDNYLLNKPVAEMQAVLAPKVVGLVNLDHATRELPLDFF
VTFSSL-AAFGNAGQSDYAAANGFMDGFAESRAALNAGRTVSIRWPLWENGGMQLDSRSRVLMQRTGMAALGDEAGLGAFYRALELGSPGVAVWTEAQ--
---------------------------------RFRELS----VSVSPAPPPH----------------QVAL----D------AVVSITEKVETKLKAL
FSEVYEERRIDARQPMERYGIDSIIITQMNQALEGPYNA-LSKTLFFEYRTLAEVSGYLAEHRAEE------
>tr|A0A0K6LAH5|A0A0K6LAH5_BACAM Polyketide synthase PksM OS=Bacillus amyloliquefaciens GN=pksM_2 PE=4 SV=1
--------------------------------------------------------------------DVIFIAQGDRYEALSAGRCQVVREDPQSYVNA
FADIQKEYGEASAILYLWALEDKSCI-----------EDYSCIVHILKAMAETGQPERLLLAGEYAS---GL--ERCYLESWIGFERSLGIVLPKTSVTG
H-FRKAG-AAITDWMRTIWDELKA-ETDHTVFLEEGKRYVYHTEPTGLTKE----NSRIRTGGTYLITGGLGGLGYLFARHLARNYQANVILTGRSPINE
---EKKEKMKDLE----NLGAGVLYAEADVCDPIGMGDCIKRAKER-FGAIHGVIHAAGIESRTSVFENEIGNFRSTLDPKINGSLLLDEWLKNETPDFI
CYFSSTSAVLGDFGCCDYAVANRFQMAYARYKNEQESGNAFVINWPVWKNGGMAVGGETGMYLKSSGQRLLETDEGIELFERIISQDNTQCLAGK-RSRA
-------------------------------ERFL-GIRRD--DSL--------------------K--TDALLETVS---RRIPEESAEKRLEADLKEL
IHSLLKIDKLVLHKNWAEFGFDSIYLAKFAALLSSHYGIEVTPALFYNYATLGDVISYYLTEHK--------
>tr|A0A0K6LIV0|A0A0K6LIV0_BACCE Polyketide synthase PksM OS=Bacillus cereus GN=pksM PE=4 SV=1
------------------KVNVSGFFYKPIWTKVITNNQDNTDNSNVLIVYPENHLIQTVKKEF-AEDRVYEIVIGSKTEIKSKKSWMIDGADDLALSSC
IANI----PSINQVYFLGGVNVSTWPRTQKTFEKIQNQSTLALFRLVKALEENKDTLNLKIITNNVYKVLEQDTVQPSTSALIGLGKTIDREYSNIKVEI
IDIDIPENSP--KQINKVLQELMVIQGVKEYAIRDGQAYKMLLTANDLDPI---QESMFKNNGVYVLIGGAGSVGLKISKYLAHKYSSHLVWIGRSEINE
---ELSRKMKEV----EEQGGTVDYYSVDIANESQVTKLFEELVRK-HSQINGVIHSALAFSVGRIQGLTEEELLNTLKAKVDGGLVLSKVLENINLDFL
VFFSSGESFNGNIGWGAYAAACNFKDALARHLQPIRNYPVHVINWGFWQGSDN----DNERILHAKGIYPITEEQGAEVLERVLGTNTSQIMA-LNVSDV
LIKMGI--DIPIREE-SEVSKF------------EQSIERKIQE-------------EQIS--AAKEVATTAVID--QELDY-SNETEIKNLVAEKIRGI
FANVLKIDKFELDADLANYGVDSLIVINLHTALEDEMG-ELPATIILEQPTIEDIAEYLIQNH---------
>tr|A0A0Q5RHV8|A0A0Q5RHV8_9BACL Uncharacterized protein OS=Brevibacillus sp. Leaf182 GN=ASG16_06490 PE=4 SV=1
---------------------------------------------------------------------------------------TVNVGEEDDIEQI
AMVLARFG----IIDHLWLAPPSEFLLHDDSLLAKQKAGVLLLFRLIKALLHAGKRLSVDVLTFQTQRAYTGDRINPVHASVHGLIGALAKEYPNWQIRL
LDLEPGWE----TSIETLLT-LPPDTEGNTWCLRGREWLCQRLAPVNLAPGM--QHNGYRKGGVYVVIGGAGGIGEVWTAYMIRRYQAQIVWLGRRRQDE
S---ISASIERVS--VSTTGPKPIYIEADAADTQSLDHAYQVIKAR-FGAIHGVIHAAIVLRDQSLANMQEDDFRAGLGAKIDVSVRLAQIFRKEPLDFV
LFFSGMMSFARRAGQSNYAAGCTFKDAFAIRLARDWPCAVKIMNWGYWGSAGIVASDEYRARMELDGIGSITPSDAMEALETLLASPIEQMAIKASKSVL
EA------------------GFAS-------ERLIDVIFDT--PGFNGDYR-SMVELPALPDLITGMIER-------------GQPVRPTGQAEPILHDL
ISRLLNVEEIDPNAEFAEYGLDTVQLAELLSKLNRRFMVEVEMQAFTDWTTLNQIAQAVSR-----------
>tr|A0A0M7AG31|A0A0M7AG31_9RHOB Polyketide synthase PksN OS=Labrenzia alba GN=pksN PE=4 SV=1
--------------GPSKHREMLPLLFEPVWAEIPRPSGRNASVQN---------------------------------------RYCVLCGVRTSHPLL
ADELERRGVTVLSLVT-----------EEAEPHAVFESCALQLFTFLKTLSGGPLKATLQVVV-------PTDRHGSLLEGLSGLLRSAALENKKWSCQL
VGTDTS----AGNFADCLEADAHTAGTQCEIRYLSGLRFVRSWNEIQPERTD--ETRPWKDRGVYLLTGGAGGVGLHIARAIADGTKPILWLTGRSAPDQ
-------VIEQQVRDLEMTGATVRYRPVDITDKAAVSALLDEIRKS-DGDLTGVFHGAGVTKDGLLSRKTETTFKSVLAPKVAGATVLDEAIGSMPIEFF
VLLSSATGALGNPGQTDYGTANAFLDRFAAWRNVQRRGRSVSIDWPYWRDGGMQMDANTIRLMDRAGVQPLETGPAIAALDVIVASVEREQVLVLEGDHA
RLREMMRPGDGSSSE---------------------------------------------------KPESTISKATMTGTSANEAGAFRRMAIVAAIKTA
FSKCLGIDRLDEESTIDRFGVDSVSALEIVEAMERDFG-PLSQTILFEFQTIGRLADELLGR----------
>tr|C6C2W7|C6C2W7_DICDC KR domain protein OS=Dickeya dadantii (strain Ech703) GN=Dd703_1430 PE=4 SV=1
----------------------ELMLFTESWQKMPHPAASRQHPKTLICFLSEPESQRLLQSRMNEQTAIVFVSRRPL--EEGVSGFHLQPKDTERYQHC
FAQLKSAGIAPQAMLYLWPLEERRQI-----------QDFAALHDLLSSMVATMAPTRLLLAGASHHS-----LERAYLESWIGIERSLTSVLPNTQCAV
ASVAVGDGTFTRQYVSMLYQELTG-QNFASVCYEGAERYVLTVQPSPVALARAVAEAGIKQGGTYLITGGFGGLGLIFARYLAQRYSARLILTGRSPMNA
ER---KAIADEL----TRLGGQVQYIQADVCDVGAMRFNLLQARQ-SLGSILGVIHTAGLEASEPVFEKSRQAFNAILRPKVEGTQLLDELLMQDPLDFV
CYFSSSAAFLGDFGSCDYAMGNRFQMGYGKHRMAQLRGKTLIINWPFWKEGKMGIRDSTEFYLRSSGQRALESEEGVQVFEQLLRQSEGQVIAGK-PSRV
A------------------RFLGTDEPPV--ARRTEHVSDVSKKRTGN----H-----AAPHNP-AQHDRQAVGSRSDLARPSGDAADIRTAVSHVLKTQ
ISQLLGVDRIGVNSSFADFGFDSITLASFSRALSQHFEVEITPAVLFGHSSVKRLTEYFCREHAQA------
>tr|A0A095H9B1|A0A095H9B1_BURML D-alanine--poly(Phosphoribitol) ligase, subunit 1 OS=Burkholderia mallei GN=dltA PE=4 SV=1
-----------------RQADPGRWFFAPSWRRGTGAPAAAAGDGVHLLFVDRGGRAAPLVDALAAGEDLVVVTPAAAFAGG-GEAYAIDPAGEADYAAL
AEALRAAGRLPARISYLAGLVDPEAAAA---DTANRFDGVHGLHAIARAFGPLEAPVLLTAAANGIHAVSGDEFLLPEQAAMAGPCRVIPLEYPHLRCRL
VDVELRAGAVLDAAGELLGAELTTADTEPVVALRGRHRWLQAVEPLPLAAPA---ASVLKPGGHYLLVGGAGGIGSLFAEHAARSPGARLTLVGRSELPA
PETWDAAAIERLRA-LRALGAEVQYLSADVADREAMTRVARTAT-ARFGAIDGLVHAAAVAGGRRIAEETPANTEALFAPKTAGLRVLDAVFDLARADFV
LLCSSLAAFAPIDGQSAYCAANAVLDSWAQALR-ARGVKAIAANWNTWREVGMARRIEVPAAFRQLELNCLAAEDGPLLFERLLGARPVQIVTPLDYEAV
AAGTAR---------------------------LARALR----GEGQGAGDDAQT---GSSTGSQGSTPAAA--RPA----LAVDYVAPASATEQALAEI
WRTQFGIAPIGIHDDFFDLGGHSLLAVQVVATIRQTLQARLDLQALFDAPTIAGLAARIDGARRE-------
>tr|A0A0F6A3D8|A0A0F6A3D8_9GAMM Uncharacterized protein OS=Grimontia sp. AD028 GN=RN22_03865 PE=4 SV=1
-----------------TGAKPESWGTAVLFALATGALAISAGG--SMLALDGKESTTYLRNLLESGATAVLQLPHALYSGE-GADVPTTPNGKIDRKAL
PDMREAMEKMPLSLSRWHELLQHPLSAT---RSSNSKDSIEQLHKLANSHDVG-NWLLLAIQA-ATIAYRGYETSLPLAFSVEPKCSLIELATSEQYCEE
LSLGNKAHHPVDQKSQTLDL--------TLVASNDEVTWLFNHDPLGLEAPL---LGVLKAGAAYVPLDSTGKPKGVMISHCCVIDTQRLNLIKDLIQTT
PSRWKLLALPQVQA-LWCYGPTVWSLEEDVTLGRNLPGYQHGQM-LPKGAVGEL-----CIGGASLAEKQFVNTEAGFVYRTGDLALLNQDDTISRIELG
EIASQIKGHDNVEDA-VVIARNNVLVAYIVSEG-EPLQKAVSGSENGWIHLSDNQAQNIDVNQNDASFVCNPLRDTAVLLNSTLAGTFSGIEADLAWPHM
PLGQSL---------------------------ITHQVN----RSSQGVGQNQII---AFVAGSDGHTPHHN--HPI----EKVMTNRPLSDVETKLKAI
WLSVLDVQDIGLSDNFFAIGGHSLLAAKVISRITDELGVSTPLKTLFTHPTLAQLADAIETSSRL-------
>tr|A0MS29|A0MS29_9GAMM BryA OS=Candidatus Endobugula sertula PE=4 SV=1
------------------KNNFELMVFEECWEARSQLSTISSKTKNCVCFLSDVESQKSLVTFMDPNINIIFVSRGDSYAKKSAQNYIVSSHHKNDYVSA
FEEIKKSIGNVEVILYLWPIEDSNYIPD-----------YTPIVNLLQASQFAQCRFKRCLLA--AQLS--HALDRCYVESWIGFERSLKLVINDAALIT
VFREFSEHETIKNWSKRLWQEMHA-VDFRSIFYQKEKSFVCRIRQISLTAE----RVLLKNKGTYLITGGAGKLGLLFARKLANMQEINLVLVGRSPINN
---DIQDCCEKINSL--SLGSKALYLQANVCNINDMKRCREKVNQ-CFGKIRGVIHAAGIQHNQSIFEKDFFDFEKVLEPKIKGTLVINKVFNITEMDFI
CYFSXSSAILGDFGSCDYAIANRFQMAYTDYQH-QSGGKAIVINWPQWKDGAMGFGEGTKMALTSSGQRLLESTEGFDMFMNFLGQKKYQLLAGK-----
--------------P----------------DRVYDF--------LGITSPL--------VNSSNNTIQTS------------IKEVNIKQLIEEDLQNY
INQLLKINQLDIKRNLADFGFDSIRLKEFAHFLTQHFTIEVTPLLFFEYPTLEKLSTYFTEQY---------
>tr|M1MRH6|M1MRH6_9CLOT Polyketide synthase PksM OS=Clostridium saccharoperbutylacetonicum N1-4(HMT) GN=pksM PE=4 SV=1
--------------------------------------------------------------------NVVFIAAGLESLRLNEDCYTVNADKQESFQQA
FRTIVNENDNISKIIYFWPYEELAY-----------VSDYKTLLHIIKALAVEQNANKLLLVGQYQNGL-----QRCYLESWIGFERSLGNMIFRTQVNT
IMFESDNLQVTEKDAEKIVLEANASNMYKSSVHNDGKRYELEVQPQTMKN----REVAIKRNGTYLITGGMGKLGFLFAKHLTKQYNANLVLTGRKILDE
---ERKSRIRELE----ELGGNVIYVQAGVCNKAEMENVIREAV-QYFTTIDGVLYMAGTANEVNILNKDVETFCQTIEPKIKGIQILSEVLEAYSVDFI
CYFSSLAAVLGDFGMCDYSLGNRFEMAYSAWLNRLISKKTIAVGWPLWRDGGMKLSGGSEAYLNVSGQRYLETEEGIALFEQLLSRSNKEFVIAGDKKKI
----------------------------------YNNLK--LQNTD-EEG-Q--------TMT-----YSKELKENHQ-----ANTHELVDTIEMDIKKI
VNEMQGIEKLDVETYLTDYGFDSIILFDFARRISDQYKIDINATTILGYPTISQIAQYLAENYTQ-------
>tr|A0MS28|A0MS28_9GAMM BryD OS=Candidatus Endobugula sertula PE=4 SV=1
------NIIPPTETSLDNIEPYEVMCFEEEWKAQLLKENTKNTSHTVICLLSEPDNQAALKSAMHSPQQLVFMSQS-DTQKNSSECFFVNPYDGITYQEA
LKNIMQVGSEIYNVLYLWAWEDSH-----------WIESSIPVVHLLQSIKASEIKVRILLAANYKT-----DLQRCYIESWLGFERSLDLVLPSIHLKV
FDISNTKKSIANDYTKTLWSELKT-TTPGSVLYKKDQRYQLSIQSVTLKDAD----SKSILRGTVLITGGCGGLGLLFAQYLAKTQGTDFILVGRSPLN-
--EEKQQAIQTLE----NLGSRVYYLQADVCDKTALQHGLVLAKEHCRNALCAVIHAAGIIDNDDIVTKNIDNFQKVLLPKIEGIRILDEVLADEVLDIV
CYFSSASAILGDSGQCDYAVANRFLMSYGNYRNTKRSGKTIVFNWPGWHVDSMLAGDDSDFYLKSSGQRLLEAAEGCELFEKIIDQSKKQFVIPGQRSRV
-------------------------------KRFLSRIGKYGDIHSTKNIPGVLDLLE-------G-VDKSGWRPEMK-------GFTIFQCIEWDLKSL
IVQQLPIHKVETESNLADFGFDSISLTAYASTLSNHYNIDVTPSIFFTYPTIARLCDYFENDY---------
>tr|A3IBP4|A3IBP4_9BACI Polyketide synthase, type I OS=Bacillus sp. B14905 GN=BB14905_00145 PE=4 SV=1
---------------------TKDLFFEKKWLHYPHDNETTKEGTTWLYFMNKDDNIVALKRMTALGIKIIEVLEADKFVQYTSEQYGIDINSEKDMYKL
FENIGLELRNLKGIIHSYTFKHLDETESIENMEKSQEEGIFSLFNITKMLLEFTHPIQLNVISSLTEQVKNNEKIIPARVTTFGLAKVISQEQPTISSYS
IDHDLDGS--SQDIASQLLRELQQDHRPELVAFRQSKRYTKVIERQSDDFN--GNEIIVRENGNYVIAGGTGYLGVQLGKFLSEKQNVNIILLARNLLPD
RMEWEKELLTSIM-EIESRGSTVTIMECDVTEEHAVKETFAKIRQD-FGEINGAFMLVKQLYHLWIKELKLSQFKKGIHNRVIGTYLVEKELNPEPLDFF
ILFSSISSLMGTKSASECCAVNQYLDSMAGYLN-QKGIKGKTMNFTLILDNKK-----------DFGSTAIPPIDFVDSLNLFFNK-------GYEWSLI
SRFD-LEQ-VHYLKP-VIKIPFG--------ESFWSE-------------------VEHFNH---SKNNQNESISMEEE---VVKSEFTLSEIEASIREI
WKTVLGISTIKEIDNFFSLGGSSLSALRFVHLFKNKFGLKFEISDLYSNPTFQDQI----------------
>tr|R7ZDF6|R7ZDF6_LYSSH Polyketide synthase OS=Lysinibacillus sphaericus OT4b.31 GN=H131_12763 PE=4 SV=1
---------------------TKELFFEKKWINYPYNNTNTKAGSTWIFFMNKDDDMVELKKMAHIGIRVIEVHKSETFVKHTDEQYSIDINSDTDMYKL
FENIGLHLKNLKGIIHSYTFKHLDETESKENMEKSQEEGIFSLFNITKMLLEFTHPIQLNVMSSLTEQIKDNEKIIPARVTIFGLAKVISQEQPTISSYS
IDHDLDGG--SQEIATHLFKELQQDTRPELVAFRKSERYTKVIERQSDNFN--GNELLVRENGNYVIAGGTGYLGVQLGKFLSEKETVNIILLARNLLPD
RMEWTKALLTLIM-EIESRGSTVTIMQCDVTEEHSVKETFAKIRQD-FGEINGAFMLVKQLYHLWIKELKLSQFKKGIHNRVIGTYLVEKELNPEPLDFF
ILFSSISSLMGTKSASECCAVNQYLDSMAGYLN-QKGINGKTMNFTLILDDKK-----------DFGSTAIPPIDFMDSLNLFFNK-------GYEWSLI
SRFD-LEQ-VHYLKP-VIKIPFG--------ESFWSE-------------------VECFNH---SKDDQDESIPMEDE---AVKSEFTLSEIEAGIREI
WRTVLGVTTIKEIDNFFSLGGSSLSALRFVHLFKNKFGLKFEISDLYSNPTFQDQI----------------
>tr|F1T734|F1T734_9FIRM 6-deoxyerythronolide-B synthase., Beta-ketoacyl-acyl-carrier-protein synthase I OS=[Clostridium] papyrosolvens DSM 2782 GN=Cpap_3714 PE=4 SV=1
-------------------------------------------------------------------NQLLWISRGNSFKQDF-NSIEMDLNNEAHFEQL
SNYVYSYDNRKIRIIYMIGEHKFPTGNDWE--YQVNSTGITALL-FAKSFAYFKSGVRFQIFSTE--RA---SEITVFQEAVVALGRSIEKEVPAFITQV
VIINPQEVS---GLGAVISKELHSEIDTRFIYYKSDKRMTYNISEMALEAP---KNYHEFPEGVYVILGGLGAIGKAVTAEIAKLSNTKIILVGRRKISD
---EIETYIEALR-----HGNEITYISADISNYIDIKRLFHEVGSK-FEKIDYVFHCAGILEDCRLPNKSVESFKRVISSKINGALAIIDMKRTYNFKKV
LFFSSTSGVFGNEGQLDYAYANMLINSLCTKQA---DPDIISISWPFWDTEGMKMPKEYKKIFSAYGFRPMPTRVGIDIVKHTLADNSKSLVLYGDRQKL
E-------------------NFSRNTN---TDKY-------IEAKD---SSA-----NTVPK--------EK-------MSANDNNDGLLDNVIIWITEI
ISKVTGIDSLTPKKSIQNLGIDSVMTTEINIEFEKVFD-NISKTLLFEYRCIKEIAEHFIQNY---------
>tr|A0A0L0JI24|A0A0L0JI24_9ACTN Polyketide synthase OS=Streptomyces europaeiscabiei GN=IQ60_31575 PE=4 SV=1
-------------------------------------------DHDWLVLADTGGVADAFAALAARGERCRLVRRGAAYTASGGATFTVDPGSDSDLRRL
LADLDRDGGPFGAVLHLWNLDAPALAACRTSLTDHTGAGAYSLIALARLLLARGDGGRLHIVTRGAQPALPGEGPEPLGAPAWGIGRVLRHEHPG---KL
IDLDPLRQPDDRAEAEALLGEVL-SDDEEEIALRDGGRRTSRLRPAGLTRP---LPLRLRTDGSYLVTGAFGALGRLLCRTLVRRGARRIILVGRTPVPA
REKWADGRAVALLRELEALGAQPVLATLDITDEDALAGWLDAHRHSGAPPVRGVFHLAGQVRDTLVADLDRAAFDAVHDPKTVGAHLLHRHLRDEPLEHF
VLFASIASLLTTAGQTNYAAGNAFLDALAHHRR-AQGLPALSLDWGPWA-TGMIEELGLDHYLHSRGMSSLSPDAGMAVLERVIAQDHAQLVTVVDWPVF
LAWY--------PSPPPL-----------VVDLAAA----------------------AAPP--ADAVSGNGFLDTF----SAADEETRRALVAERFAAL
AATVTGTDRIDPATGLGELGLDSLLAMELRARIHAELGVALPVVALLSGTPAGELAAQLHDGL---------
>tr|H1XP67|H1XP67_9BACT Amino acid adenylation domain protein OS=Caldithrix abyssi DSM 13497 GN=Calab_2572 PE=4 SV=1
-------------------------------------------GNRWLVFSDGTSRSEQFIQMLNKGFECFTVIPGEENEFHDDLTLILNPTKFEEAQKI
IDPLISD----TEILYLWSLNPEIPNEKLYALSNALSLKRFWLVLLGDLLFNFASNSRLISQIDVDTP-DPRTLFKALLLPDYEQRLSIRHKISA---PE
MSLKTVYEPDVEVEIKALIGIIF-KTGQRVMGLIDNGFKKYGLTR-DFILP---MPKELTFANSFALLKDFGRFIELNPRDIVYHNLRYNIAFFA--V-D
LENLSQRISSEVQKKFESQTYQPLPAIHKLQKSTSIEKFVLNLEQQSVKSASTLYLVVGSKRYLMNQGVHQIDFDSFSADGIQGVLLNPQHLLGLALDFF
ISVSRFSLPEKKAGANEF-GLNNYLLALHKKRL-LAGLPSLHVQLGGAV-PDEM---SI-------------ALGRWSILNELIPVEKGHLITETNWANI
FGSK--------PQIPPL-----------LRDILFK----------------------EQPE--AGSEKGAKDIDKKE--VLALNPEERFDVIRDYLTYV
LAGVIPASQINHELSLSQFGIDSLMAIELKNTVESQLGISVPIATLLKGPSINDLTNLTLDQI---------
>tr|H8FPU2|H8FPU2_PHAMO Putative Aspartate racemase OS=Phaeospirillum molischianum DSM 120 GN=PHAMO_20066 PE=4 SV=1
------------------------------------------ADELASILAEISGFDATTAQLTDMGLSLMLLKLGQTV----EHRFGLELRTVNDLAAY
IQRHATAVPAPAPVIQTAPPSVPVMPVAPVALPPMDGAGIAPVLQFLSQVAAQARQQMAWLGQGGLPAAPPAAPVVPVKPPASSIAKPLSEQQRTFVSGL
VERHVVRTHS--------SKELTQDSRAVLADWKHTLSFWGQLKEAKYPIVRSEGARFWDVDGNEYIDVAMG-MGV--------------HFFGHKPAPI
HDALIRGTQSALTGAFGNTGSEAVMVALRLARAVTGRDRIVIFDQDGEIVPVGLGTPAGMIRDVTVLDYGSPEALDIIAAQ-------------------
--ADSLAAVLMEPVQSPDLQPQAFLSRLRRLTE-QHG---IALIFDEIHPGGAQAWFGVQADIVTYGK---IVGGGLPI--GVIAG-KARFIDYIDGGAW
QYGDRSG-------PQSAMIYFGG---------TF------CRN------PA------TMATTLA------ALTVM-KE--AGPTLQERVTARTVAFCDA
LNLWFELKHFSSQWRLVPLGESDFQPLEIELMIERGVYTWERRINFFSDDDVARVLEVI-------------
>tr|I8U1X2|I8U1X2_9FIRM Amino acid adenylation domain protein OS=Pelosinus fermentans JBW45 GN=JBW_04656 PE=4 SV=1
------------------------------------------GKKTWLIFAQQEGIGDLVAKLTERGETV-LIYPGQSFQCLSEDTFSINS-SQEDLKQL
LHT--VL-DVCHGIIHTWSGSNDKNNITTVDLEKAQNLGCLHVLQLIQIIQELRALPRLWLITRGSQAV--GEPVDFIQAPLWGLGRTIAIEQKELWGGL
IDLDPEDQGEQ------AADDFVQGG-EDQVAYRQKTRYVARLKR---HSLDRNNPFYWQRNGTYLITGGLGDMQV--------------ALMGRTELPP
RTAWDSGTIKELE----SMGASVHLAAVDVADEEQLKNFLVSFREEGWPPIRGVVHAAGTVADQLLTECDSGSFNKVLRPKVQGAWQLHQLLKDVPLDFF
IVFSSISTVVSSPRLGSYAAANAFLDALMHYRR-NLNLPALSINWGPWAEIGMAARFNILSSTTSMGINALTPACGLQILDNLINT-DMTVVMDVDWERW
RIIYQQI-------GKSELV--AD---------LL------LEE------SE------AAGTVSN------AINQE-SS--IRKELGEHYNLLESYLCEQ
VSQVLGMAKLDVHTSLNSLGLDSIMAVELKNRIEKALDVMVPMVYFLQGPSIAEMIAKI-------------