>seq_1
NWSYQKKWIPAPLDAADKQIVGDVVIFADPLGLADQLKSFANSEQTYITVEPGQAFKQLTHTHFIIHPNRPSDYEQLFETLRSYGVSVKHIIHLWNYTNQ
EDKLYVSKAKQAQKTGSMSALFLTKAISVYEEQVAITFVSTHAMNVPEDHIHDVEKATTAGLMTAVQHEWPFIKVQCLDFSLAESVSSHSHAMAMMAELT
HDQDCHVAAYRQGVRYIPFLAPLHLEKEQKRKEPPFESSGLYVITGGLGGIGRLVSEQLLTSYQAHLVLLGRKEREALSSDQQETLSLLEKQAKVHGGKV
LYEKADITAEKEVEAIISRHEVAGNRRLDGIIHFAGIIQEELLADMTSVSLNDMYEAKVYGTIALHEAASKRRNVLFLSSSSARTLKGGMTVGAYCAANE
FVEQFAHYQKLTSTVKPYCFSFSMWDEIGMSEGSMIKGMLKERGYLPISKQAGFQTMLACLMTDAPLIYTGLDRSKKEIHEMIHADAEMQTEQTFYVFFK
TDQTKAVEERLYQSIHTCLQSRLSGEYAVHLFPEEYWKETEDGSPDEAYFHELIEESGMDADNRAPHTETEKLLAHIWSELLDVSDVSCGDHFFLLGGHS
LKATQMLSAVRQKTGFDVPLAVLFEHTRLGELADWIDSNAKADEVIPMRE
>tr|K2MKW1|K2MKW1_9BACI Nonribosomal peptide synthetase subunit OS=Bacillus xiamenensis GN=BA1_08356 PE=4 SV=1
DWSYQKQWTPAPLDAADKQTIGDMVIFADTLGLADQLRSLSNSEQASITVEPGQTFKQLTHTHFIIHPNRPSDYEQLFETLRSYGVSVKHIIHLWNYTNQ
EDKLHVAKAKQAQKTGSMSALFLTKAISVYEEPVAITFVSAHAMNLPEDHTHDVEKATTAGLLTAVQHEWPFIQVQCLDFSLTESASSHSHASAIMAELT
HDKDSHVTAYREGVRYIPLLTPLHLEKEQRVKKPPFEASGLYVITGGLGGIGRMLSEHLLTTYQAHLVLLGRKEQEALSAEQQETLSLLKEQAKVYGGTV
LYEKTNITDAKEIEAAISRHEVTRDQRLDGIIHFAGIIQEELLADMTSVSLNKMYEAKVYGTIALHEAASKRQNVLFLSSSSARTLKGGMTVGAYCAANE
FVEQFAHYQKMTSTVKPYCFSFSMWDEVGMSEGSMIKGILKERGYLSMSKQAGFRTILACLMTDAPLIYTGLDRSKKEIQEMV--DAEMQTEQAIYVFFK
TDQTNAVEERLYQSIHTCLQSRLSGEYTVHLYPEEYWKETEDGMPDEAYFHELIEESGLDSENRAPQTETEKLLAHIWAELLDVSDISCGDHFFLLGGHS
LKATQMLSAVRQRTGFDVSLAVLFEHTRLGELADWIDSHAKADEAIPMRK
>tr|A0A081L7S4|A0A081L7S4_9BACI Peptide synthetase OS=Bacillus sp. DW5-4 GN=BA70_09620 PE=4 SV=1
DWSYQKEWTPAPLDAAEKQIVGDIVIFADALGLADQLKSLSNSEQTYITVEPGQEFTQLTHTHFIIHPNRPSDYEQLFETLRSYGVSVKQIIHLWNYTNQ
KDKLHVAVAKEAQKAGSMSALYLSKTVAVYEEPVEITFVSAHAMNLPEDQTHDVEKATTVGLMTAVQHEWPFIKVQCLDFSLTESASSRSHASAIMTECT
YDKRSHIAAYRGSVRYIPLLSPLHLEKEQKMKKPPFESSGLYVMTGGLGGIGSLLSEHLLKSDQAHLVLLGRKEREALSAEQQDILTSLEKQAKDHGGTV
LYEKVDITDAKEVEALISRQEVARGKRLDGIIHFAGIIQEELLADMTSVSLHDMYEAKVYGTIALHEAASKRQNVLFLSSSSARTLKGGMTVGAYCAANE
FVEQFAHYQKLTSTVKPYCFSFSMWDEIGMSEGSMIKGILQERGYLPISKQVGFQTMLACLMTDAPLMYMGLDRSKKEIEEMV--HAEIQKEQAIYVFFK
TDQTKAIEERLYHSIHTCLQSRLSGEYSVHLYPEECWKETEDGMPDEAFFNELIEESGQNSEDRAPQTETEKLLAHIWSELLDVSNISCGDHFFLLGGHS
LKATQMLSAVRQRTGFDVPLAVLFEHTRLGELADWIDSHAKADEAILIRK
>tr|A0A0P7G794|A0A0P7G794_9BACI Non-ribosomal peptide synthetase OS=Bacillus sp. NH7I_1 GN=AKG37_14140 PE=4 SV=1
DWNYQKKWIPAPLHEAEKRTAGDIVVFADTLGLADQLRSLSADEQTYITVEPGQAFTQLTHTHFIIHPNRPSDYEQLFETLRSYGVSVKQIIHLWNYTAQ
EDTLHAAMAKEAQRTGSMSALYVTKAIAAYEEPVEITFVSAHAMNVLEDQTHHVEKATTAGLMTAVQHEWPFIKVRCLDFSLTESDAAHYHALSIMTELT
HDTSQHIAAYREGVRYIPFLSPLHLEKEQRMKKPPFESSELYVMTGGLGGIGRMLSEHLLSSYQTHLVLLGRKARETLSAEQQDVLNSLEKQAEKHGGTV
LYEAVDITDAKAIEALISKQEVSLGKRLHGVIHFAGMIQEELLRDMTSVSLHAMYEAKVYGTIALHEAASKRQNVLFLSSSSARTLKGGMTVGAYCAANE
FVEQFAHYQRLTSTVKPYCFSFSMWDEIGMSEGSMIKGMLKERGYLPIPKRAGIQTILACLMTDASLIYMGLDRSKQEIQAML--HAEIQAEQAVYVFFK
TDQTKAIEERLYQSIYTCLQSRLSGEYTLHLYPEEYWQETEDGMPDETYFNELIEESGHDSEDRVPQTETEKLLAHIWSELLEVSNISCGDHFFLLGGHS
LKATQMLSAVRKRTGFDVPLAVLFEHTRLGELADWIDSHAKADEAIPMRK
>tr|A0A0K0I2S2|A0A0K0I2S2_BACPU Long-chain-fatty-acid--CoA ligase OS=Bacillus pumilus GN=B4107_0343 PE=4 SV=1
DWSLQKKWTPAPLHEAEKQTEGNMVIFADTLGLADQLKSLSGNEQTYITVEPGQAFTQLTHTHFIIHPNRPSDYEQLFETLRSYGVSVKQIIHLWNYTTQ
EDTLHASLAKEAQKTGSMSALYVTKAIAAYEEPVEITFVSAHAMNLPEDQTHDVEKATTAGLMTAVQHEWPFIKVRCLDFSLIEPDAGRSHASLIMTELT
HDTSHHIAAYREGVRYIPLLIPFHLEKEQRMKKPPFESSGLYVMTGGLGGIGGMLSEYLLTSYQAHLVLVGRKAREALSMEQQDVLISLETLAEKRGGTV
LYEKVDITDAKAIEALISKQEAALGKRLHGVIHFAGIIQEELLRDMTSVSLHAMYEAKVYGTIALHEAASKRHNVLFLSSSSARTLKGGMTVGAYCAANE
FVEQFAHYQRLTSTVKPYCFSFSMWDETGMSEGSMIKGMLKERGYLPIPKRVGIQTMLACLMTDAPLIYIGLDRSKQEIQEMI--QGEILTEQAVYVFFK
TDQTKAIEERLYQSIYTCIQSRLSGEYSVHLYPEEYWKETEDGMPDEEYFNELIEESGHAAEDRVPQTETEKLLAHIWSELLDVSIISCGDHFFLLGGHS
LKATQMLSAVRQKTGFDVPLAVLFEHTRLGELADWIDSHAKADEAIPIRK
>tr|W6I1W5|W6I1W5_BACPU Nonribosomal peptide synthase OS=Bacillus pumilus GN=BPJ03480 PE=4 SV=1
DWSYQKKWTPAPLHEAEKQTAGDMVIFADALGLADQLKSFSNNEQTYITVEPGQAFTQLTHTHFIIHPNRPSDYEQLFETLRSYGVSVKQIIHLWNYTNK
EDTLQVALVKEAQKIGSMSALYTTKAMAAYEKPVEITFVSAHAMNLPEDQTHHVEKATTAGLMTAVQHEWPFIKVRCLDFSLTESA-DHSHASAIMTELT
QDTSYQVAAYREGVRYIPLLTPLHLEREQKRKTPPFESSGLYVLTGGLGGIGRMLSEHLLTSYQAHLVLLGRKAREALTADQQDVLTSLEKQTETRGGTV
HYEEVDLTDAKALEALISRQEVAHEKRLHGVIHFAGIIQEELLADMTSVSLHAMYEAKVYGTIALHEAASKRQNVLFLSSSSARTLKGGMTVGAYCAANE
FVEQFAHYQKLTSTVKPYCFSFSMWDETGMSEGSMIKGILKERGYLPIPKRAGLQTMLACLMTDAPLIYMGLDRSKQDIQEMIHA--EVRTEKEVYVFFK
TDKTKAIEERLYQSIYTSLQSHLSGEYSVHLFPEEYWKESEDGMPDEAYFKALIEESGQDAEDRAPQTETEKLLASIWSELLDVSNISCGDHFFLLGGHS
LKATQMLSAVRQRMGFDVPLAVLFEHTRLGDLAAWIDSHAKVDEAVQMRK
>tr|N0D686|N0D686_9ACTN Uncharacterized protein OS=Streptomyces fulvissimus DSM 40593 GN=SFUL_6816 PE=4 SV=1
GVAYSRVWTADVLLPGTPELLGALLAPARPVGTYADLSGFLGSGDRVVWVPGG--EVRLVPLTAEVDPGSPEAYAQLGAALRRAGIESLEIAHLWALGPR
AESEETGDILGAQARGVFSVQNLLRELPA--AGVAITYAAVFTRDALGGLPPGYASAPLAGFVRSEGHALTHI-----DLSGR----YDDLAALFAYEAA
QPLDGRSVVLVDGLRHKQAVEPLTLPATG---TTLDGQDGFLVVTGGLGGIGRILVALLLRRFRRNVLVLGRREAPAVRD----RVAAFESIAREHGGAF
TYAQSDLQDPALLRETIRQHAASSGQPLHGVFHLAGMVHEALVADQSTEELTEVFKPKVAGLHHLGGLLAQEHDAFLVTFASARSLAPGATVSAYVAASD
FAGHYSAHLR-SQGIRATSVAWGVWDETGMSENLRVNRALHRRGIETIEPLQGLGALLDALRTDRPAVHIGVDGSRLPHGLAVGDQDGEPQPTCVVTDFG
------DFERLFVAVEDAVRGHLGGSR-LRYEILDELPVDRNGLVDRDMVLDRLDVLRGAVTVEPPRNATEERIRDICRAVFRVGTIGVTENLFDLGADS
IATIQLLARLRDDGVAVVSHEEFYKEPTVRHLAEQAAAGPDVPAAVVPRA
>tr|A0A0M4DVP9|A0A0M4DVP9_9ACTN Uncharacterized protein OS=Streptomyces sp. CFMR 7 GN=ABE83_01780 PE=4 SV=1
GVAGSRVWTADVLLPGVPELLEALLAPARPVGVYADLTGFLGPADRVVWVTGGSHAVRLV-LTAEVDPGSPEAYAQLARALRGADIDSLEIAHLWALGAP
----GDGDILGGQARGVFSVQNLLRELPA--AGVTLTYAAVFTRDALGVLPPGYGSAPLAGFVRSEGHALTHI-----DLSGP----ADDLAALYETEAS
QPYDGLSTLYVDGLRHRQAVEPLTLPATG---VSLDGEEGFLVVTGGFGGIGRILVALLLRRFRRNVLVLGRRDASAVRD----RISEFEAIAREHGGVF
TYARSDLQDAAQLRETVRDHATASGLPLGGVFHLAGMVHEALVTEQSTEELTEVFKPKVAGLHLLGDLLVQEHDAFLITFASARSLAPGATVSAYVAASD
FAGHYSAHLR-SRGIRATSVAWGVWDETGMSRNLKVNRALHRRGIETIEPLQGLGALLDALRSDRPSLYVGVDGSRLPQGLTVEEPA--HETACVVTDFS
------EFERLFVAVESAVRERVGGSRPVRYAILDELPVDRNGLVDRDMVLDRLDVLRGAVTVEEPRNATEERIRDICRAVFRVGTIGVTENLFDLGADS
IATIQLLAKLRDDGVAVVSHEEFYKEPTIRHLASQATADSDTPTAVPATA
>tr|A0A0F7FZN4|A0A0F7FZN4_9ACTN Nonribosomal peptide synthetase OS=Streptomyces xiamenensis GN=SXIM_47760 PE=4 SV=1
GVVDVRVWTSEVLLPGTRDLLTALTAVPAPIGAYRDVGRFAADPADVVWAAPGAD----SVLVTEVDPRDEEAYRSLASTLRAAGADTVAVAHLWAMDTG
G-DDGHRDVLDAQDRGVFSLQHLWRLLPE--AGVTLTRTTVVTRAALGPLDPGYRAAAVSAFVRGEGHTAVHI-----DLSGT----GGDVVEVVRREET
TAADGTSVAYVDGVRHLQGLEALPLPEGP---SPLALRDGFVVVTGGLGGIGRLLTAFLLRHFGRDVLVLGRRDPERAER----EIAELRALAREHGGAF
TYRRCDLGDASALRAAVEGHAASSGLPLQGVFHLAGVIHEALIAEQSVADLRAVYAPKVRALHLLGELLLERHDAFLVAFASARSLAPGTTVSGYVSASD
FAAHHAAHLR-SRGLAATSVAWGVWEETGMSRNLRVNRSLSRRGIGTMDPLRALLALSRAVGTDASGVHLGVDGARLPSSLPVREDRPDLDDVCVITDFA
------TFEEAFAEIAAALRPDH-GDRPPRYALLDEVPLDRNGAVDRSAVLSRLDVLRGEVTVEGPRGPLEERIRDICRAVFRVDTIGVTENLFDVGADS
IATIQLLARLRDENVVQVSHQAFYAEPTIRHLAEQAAAAEHRAGEPAPPR
>tr|H8MSA9|H8MSA9_CORCM Putative non-ribosomal peptide synthetase OS=Corallococcus coralloides (strain ATCC 25202 / DSM 2259 / NBRC 100086 / M2) GN=pks
GSVYRRNWVPHGLTPVQA-LPDTVVVFAPAGEPGKRLTAALATGQRVLVVEPGTGFALNGGDRLTVLPGDAGDAARLVEHLA-DTAAGAPLIYAWPLAGR
SGTESFDATEAL-LALLPPL---ARRFG---KNHPRLLAVTHGAATGELL-GDPKAAMIGALLRVVREET-RAAVRAVDIDSL----E-AFAEVVLGELT
DPSGEVECAYRRGLRRVSRLEPVRLQEQ----GGTLRQGKRYVVIGGLGGIGRALVRYLVTAFGARVAILGRRAERALDPASAA---ALTGLRQL--GAV
TYGAGDVSDGDGLRGALARASESLGGTPDGVFHLAGGFFEQPLEQLELGKALGGMIAKVSGSREVVEAAEALGIPWVALFSSVNGYFGGPGLATYAAANR
FQEALAGSWNG-KRTRVCTLAWSMWDETGLSRGYANKELTRERGFVVFSPDAALQLLDSALSQAQDTLFIGLDATRPRMRVEL-DMSPEPLT--CLTART
SAEP--R-------AIHALGDAFGIELTVRPRSSTAAPAKAAGVEAL------------AARTATDPAAIAEQLTALWCDVLKLEELAHDANVFDLGAHS
LLLPNMQGRIRESFGVEPTVVDLFQYPTVAKLTAYLASR-----------
>tr|A0A093SZ49|A0A093SZ49_9ENTR Uncharacterized protein OS=Pectobacterium betavasculorum GN=KP22_16090 PE=4 SV=1
NQIFRRLWQPLAISETSL-PVQRILMFCAETCNLADVEKAFAGTDQLRIQDSSSQFEWTEAI---------------QAQLN-SQQPVSHIIYIAD----
SD--ELTIAEQA-TSLLAPLLALLQTWE---KALPLTVVTLHGQYHTDQP-VNPVNSLVTSLVRSAREEIPRLSCRVVDMTDI----SQMTVEDLLTEIR
SSAQDSEIAWRDGLRYVSRLARLKISGN----GADSSINPKYVLIGGLGGAGSILAERLAQNADAHIWLIGRTPVENMNAESLM---RLARLKKVS-THV
HYRVADVADYPNIAEIIAQIQAAEGGNIGRIYQLAGSFRQWQIKEINPAEDFALLDSKVQGSSNLYTIAKEFSVPSLVFCSSANGYLSGAGVALYAVANR
YQEALAELAQQEAQLHVTSAGWSMLEDTGLSQGYVHKALTEAKGYIVADPHQAIALLDPVIASGEHACVVGLNPDAPAMAGEF-WFKPMADV--AADSAE
SC----------------------------------------ANQAE------------ETAGDNSADAVAEKIATIWQELLDLDELGWDENLFDLGANS
LLLPQVILRIERELGFRPALVDLFQYPDVASLAEFVSDN-----------
>tr|U5WXG6|U5WXG6_MYCKA Uncharacterized protein OS=Mycobacterium kansasii ATCC 12478 GN=MKAN_02195 PE=4 SV=1
------LCTPTLESATPG-PALPVLLLSDREEFTAALAQALRS---RGHALSTSAFELTDAQERRRIR-----------SLL-DGGP-EHVVHVLPVGPP
TP--EV---AGR-CADLAALLRVMEQTG---GSV---VA---------PT-GCEYGQSLAAFAHSAGRDLPRLKVRFIGSAVS----PEAVADELSR---
--EEPAEVDLGLPVRRILAAAPIRAAGE-----SALQRAGRYLVIGGLGGVGRHVCEYLLRQFGAHLLVVGTSELDCTQPAGPRG-RNLLALREM--GDV
TYLAVDVADAMALRAAVEVFEQQHGGPIDGMFALAGELVPRSAVQLSAADIDDMLYAKGRGAIAVERLLAERAHAIEVYFTSVHSLVGAPELAAYAAANR
FQDVLAARHRD-RGRRAWSIAWSRWAGPGMSLDVAGGDLAAEMGLATIDPAVGIDALDAVLRSRPGWYAVGLDTGNRRLAHLAGGLRPLERI--EVRMA-
GPAT--D-------VTAAVTDAFGVPVPAHVVGQQ-----PAGPPAP------------A--AAGDQGSAMAVLAGIWAELLKLPDVSAADDFFELGGHS
LLVPRLQERVLQLLGVALPAVAVFEYPTLRELARVIEDR-----------
>tr|W5WF89|W5WF89_9PSEU Uncharacterized protein OS=Kutzneria albida DSM 43870 GN=KALB_6152 PE=4 SV=1
NWFFDRAWLPAEQEARAELPTGPWLLL-APDGAQIPA------EDNVII-VRQHEFD---GD-----------YLTLVER-----HKPSVVLHGFGLARG
EG----DQL----HTGVYSVRGAL--LA---G-VQLLVLTQGGSWREGDR-VDVAKAALPGLIRTAAAERVLPVVRQIDVDGG------DLLAVVRAELA
ARGQNDLVSYRDCQRLVPRLRPVAVGDDL---PPNVRVGGLYLLTGGLGGIGYEVAQYLLAAYQAKLLLVGRSEV------GPED-ERLADLQAL--GEV
EYRSLDVADSAALAAAVTEAERAHG-PLTGVLHLASADVQHTVAREPLSAFSGIYQAKVFGTLALAELLEDRPEAVLVLFSSVNGDFGGSSFGAYSSANS
FLNGFADHWGRERGRPVRCLAWSMWAGVGMNQGSPTA-AAASRGFRAITDEQGLESLLFALATEHVHLLIGLDGRNEHIVRELAPEQLRNSE--IVLAHT
GPEI--DPA---ALS----EVVRRSPLPVRILAVREIPRDAEGGVDQARLLAAVDRPSGGHRHVEPATELERKLAELWAEVLGQQRIGREDRFFDLGGSS
LRAAQLIARTNSALGTRLLVHQLYEHPTIGELAPVLAKE-----------
>tr|T2S2F2|T2S2F2_SACER Peptide synthetase OS=Saccharopolyspora erythraea D GN=N599_07620 PE=4 SV=1
NWFFERVWTAQSIVESES-RAGVRVLFADVEREQWLG------EHDVVV-LPGTRFARD-GNRFSIDDANPAHYRELLTAVRSDFGRIDAVVHAWAAT-P
GG----AGL----RSGALSVRMLL--LA---SWPEVLVLTTGGVRGDGDA-VDVAKGALPGLVRTAVAEGAVPVLRQVDLPAAT---PERWAAIVRAELD
AVPDADVVAHRGGTRLVPRLRPVEPEAGS---SPALVQGGVYAITGGLGGIAQQIAEYLLAAYQARLLLIGRSPVAEG---TPKA-ERLADLRTL--GEV
EYRALDVGDTAALHSAVAQAERRWGRSLDGVLHLASNDVEHTVARASRGEFARTYRAKVHGTMAIAEVLRDRPDTLLVLFSSVNAEFGGSSFGAYSSANS
FLNGFADHWGHELGRPVRCLSWSMWTGSGMNRGSPSA-AAASRGFVPIDDASGLSSLLTALGQDRVNLLIGLDGRNEDIIAELAPEHSRSTE--IVVAYS
GAGV--DEA---ELREATAELVARCEAPVRFSRVDRVPRDAAGRVDQAGLLAAAASAGERRRYAEPETDLERRLAAIWGEVLGRERVGRDDAFFELGGNS
LRAAQLVARINGTLPARMAVHQLYDHPTVGRLAEVLDKA-----------
>tr|B4XY94|B4XY94_STREG Azi1 OS=Streptomyces sahachiroi GN=azi1 PE=4 SV=1
APDSEASVPALAVVWEPADPDGPLVACVSGDVPDWLP------VSTAQIVV-GP------D-AV--ELASA--LERAFATAGEDEGAVPQVLFVAASDPA
TA----GDA----GVLSEFLA-V---VA---RIAELTVLTRGAVPAPGDT-VVPGRTGLTALVRTARSERLLARTALIDAPADA---GA---AELAALAT
VRHSGDVIAVRDGRPLQQRLRAVPLPEVFDVPADVLPRGGTCLITGGLGGLGRAVAEHLVVTHGARLLIVGRTPQERLD--TGAR-EALEVLHAI--GEV
RYRTADAADPDALAGAVAEAEASWGCGLDLVLHLAGAAVDHELRAESAQWLATMLHPKAGGCAALDGVLATRPDTAVVLYSSVNGLFGGTGFGAYAAANA
VLDGWAQRWAA-AGRRAQSLAWSMWDGPGMNQGSPLVAAGRHRGLTLIDPTRGTLALLGALHAGPVHLLIGADPANEQIKPLLAADQLGGGT--VAVAVV
PADT--DPQ---QVRAAVSAQLADRGIFARVVVTSRIERDRSGTPDPAAVLAAGAGGAS---YLPPEGRLEALLAEAAAEVLGVARVGRDDSFFSLGCDS
IRAVQLAEALSGQLDSPVSVGSLYESPTVRSLAARIAG------------
>tr|S5TV27|S5TV27_9BACT Long-chain-fatty-acid--CoA ligase OS=uncultured bacterium esnapd17 PE=4 SV=1
AWLLERVYAPAPVVPAPLDADDPLAGVLAQRFPATVI------VD--QECR-GT------DDGVALDLRDAEQHRRALS---YLESVPARVIYCLAASP-
-A----DLD----GPATELLL-A---LA---EAADVTVLTRHALRDERDL-VDPARATLPALVRTAQAEGTVGAIRLLDVPVDV---DA---ADILAAGQ
-PAGTEIAAVRDGTAYVERLRVVEEPPGLAIPADLLRPGGTVLLTGGLGGLGAQVAQYLLAAVSARLLVVGRTPEAQLT--PARA-AVLEELRDL--GEV
DYVALDVADAGALRDAVAKAEQRWDAPLDVVLHLAGVDVAHTLANEQPAWLADMLAPKLGGARAIDSLLAERPDTSVVLFSSVNGFFGGSSFGAYAAANA
GLDGYALRWAA-QGRTARSLAWSMWTDTGMNQGSPLTAAAEHRGLRAIDASRGLALLLATLNQDRPYLLVGADPDHDAIRPLLADDQLDGAE--IVVAVV
GDAA--AQA---AVSHVP-------G--VRVVGVQEIPRHADGR---LNVKALGPARRA---YDPPEGELETAIAEILAEVVKQERVGRDDSFFTLGGDS
LRAMQVVGRLKERLREPVPVSLLYEHPSPRELAAALSG------------
>tr|A8CF88|A8CF88_9PSEU KtzG OS=Kutzneria sp. 744 GN=ktzG PE=4 SV=1
TRLVTREWTELPSSPAADDETGVRLVLGDDSDRERLG------IDTVVSVRRGDGFGQDAPGRYQVAPGDRGQLRSLLRAVTERHGRIASVVHAFPLARG
GE----RLL----AITTELTALL---T-----EVRLLVLTAGALWRDGDS-VDLGACALPGLIRTAVSEHPTMRVRQLDLPAD----DGEWAQAVRRELA
DRNHAGVVAARDGRRWQPKLTPLAETETET-VTAPVRTGGRYLVTGGLGGLAVEIAGHLLAAYGVRLLLVGRSTVD-----GAKA-DRLAELSAL--GDV
DYVQADVADAGALEAAVASAEARWGHGLDGVLHLAAADPRHTLANEAAATFAEQYRPKVSGTLAVAAVLDRRPDASLVLFGSVNGEFGGNSFGAYAAASC
FLVGFAEYWRHERRRSVKCLAWSMWTDVGVNAGRPVE-AARRRGFRAIDPDAGLRLFLDAMAAPGHYLLLGLDLANPTIVADLGPGGVHAGE--LLVAYA
PDGV--DPG---VVRAAIAAGIRDAVVPVRLVALPRIPRGVDGSVDTERLLLDAPGRRRRT-PAAPRSDLEREIAGVWSAALGRTAIGRDDSFFELGGNS
LRATRLLALVDDRLGVRVSTQELYESPTVAGMAAAVRER-----------
>tr|D9WMP9|D9WMP9_9ACTN Involved in polyketide synthesis OS=Streptomyces himastatinicus ATCC 53653 GN=SSOG_07629 PE=4 SV=1
PWVFRRQWTEIPAAPDAPDGTGVRLVIAEEEDRARLR------VDPLVAVDRGGEPTRRAPGHYAARTHDRGELRRMLAAVTADHGPIGTVVLAPPLSGG
AD----RLA----AATAELSALV---AD---GEPLLLLVTAGAQYRDGDT-VDLGTCALPALVRTAAAENPRLVIRQLDLPAE----ADAWPAALSAELA
DRDRTGVVAVRDGRRRQPRLAPVERDGAD--PAPPLLAGGLYLVTGGLGGIGHDIAGYLTAAYGARLLLVGRSPAD-----GEKA-ARLAELTAL--GEV
VYRQLDVTDAAALEAAVTDAETRWGRPLDGALHLAGADPRHTVANESGEVFAAQYGAKVAGTLAVAEVLATRPDASLVLFGSVNGEFGGHSFGAYSAANG
FLAGFADHWHHERRRAVHCLAWSMWSGIGMNRDQPAA-PAHSRGFRSIDAPDGLRLFLEAISVPHHYQVVGLDAANPAVMDELVPEQLRTGE--VLVAYT
ADDI--DPE---TVRAAVAPSTRDRPVPVRLVRVDHLPRDAAGRVDTARLLAEAVGKPGRRTVTPPADDLERRVAALWSEALNCPEVGRDDSFFDLGGNS
VRATRLLALVDDAFAVRVPTQRLYENPTVQAMAAVVAEA-----------
>tr|A0A0M3U7F4|A0A0M3U7F4_9PSEU Uncharacterized protein OS=Pseudonocardia sp. EC080625-04 GN=FRP1_29800 PE=4 SV=1
AWTLSRRWTVLPDVSATDDSRGAVVVLADGD-VPVDD------GRTVVAVS----------------RGDTESVSAALTGVARRYGSIDSVVLAWTLPNQ
SR-----------EAAEEYTAMFLSATA---AAASLLVLTQGAVHVDGDH-VDLGAGVLTGLVRTAGAESPVVLTRLVDLPEN----RSEWGRALTIELG
DRETAGVVAVRDGVRWVRRLRPLSGDDPE--GSSPLTAGGLYVLTGGLGGLGYELASYLLGAYNAKVLLLGRSPAE-----GERA-ERLRELHEL--GEV
GYHAVDIADTGAVVDAVREAEQRWDRTTDVVLHLAGADPRHTLLTEQQATFDYFYRAKVAGTVTVGHLLEDRPQAKAVLFGSVNGEFGGNSFGAYSAANS
FLTAFADHWHHERGRDVRCLAWSMWAKVGMNAGQATG-AVEQRGFRVIHPDEGLETLVEVLRSGHRQLVIGIDTTNPQIIPEMDGDVLGANE--LVVAWT
GADC--DPV---AVERAVADAGRTCPVPVRPVRLAKLPVTVHGAVDVAQLLLDAATACDGGEVVEPIDPLEVRVAAVWSEILNRARVGRDQSFFDLGGSS
LRASQLLSALDDRLSVRVRTQELYENPTVAGLAEVLEQR-----------
>tr|D6A434|D6A434_9ACTN AMP-dependent synthetase and ligase OS=Streptomyces ghanaensis ATCC 14672 GN=SSFG_06825 PE=4 SV=1
SWLFTTKWVRATADPGPA-GSGVWLVFGEGDLAARLRA--ARPDGPVVPVTTGTTFLRDA-GSYRVDPLDPAHHAELLAAVRREHGTPGALVHAWATGAG
SA----GTR----GPDLP--AGSLHSL-----GLPLYVVTNGAL-TPDDP-VEPVHATVNGLVRTANAEGGAPWVRQLDLRPDD---P-DPAASVLAELG
DRGADEVVARRDGRRLVPRLTPLHEAAPD--ATHRIRPGGLYLLTGGLGQIGVRLARFLLTEHGVRLVLTGRTAPT-----GDRA-GRLAELAGL--GDV
VHHQADVTDLDAMRAAVAGAEQRFGQELDGLVHLAGAGFAHLLTAEDAAEFRRMFQAKVTGTEVVAEVLRDRPDALLVLFSSVNGHFGGTAFGAYSSASG
FLPAFAAHWRR-LGRPVQCQSWSRWTTDQ-DGGVGLE-ALRRHGYREIDPEHGVRLFRTALADPAEHVLIGLDDRNEHIARELDPAFLGPLQ--VTVSYH
GQPG--DR-----VRQ---------------AVVSAVGSGVAVRV--EPAQ-----AAQGGDGPEPVGELEHAVAEIWRAALRSTSLNSTDHFFEQGGNS
LTAMRLVDRLNVAFDVQLTVQHLYDHPTVEKLAREIERL-----------
>tr|A0A0M9YD45|A0A0M9YD45_9ACTN Uncharacterized protein OS=Streptomyces sp. WM4235 GN=ADK55_30005 PE=4 SV=1
AWLFERRWGPAPAAAPAPRADGVRVVLAEDTDLTRLA------VDSVVTVRRGAGPVREAPGRYVAALDDRDALRLLLATVAADHGPVGTVILTLPPEPD
GD----RLA----RATAEFAALA---AD---GAAGLLVLTSGSVHQDGDT-VDLGTCALPALVRTAADEDPGRPIRLADLPATD---PGAWPAAVRGELA
DRDRRGVVAVRGGTRLRPLLAPVAPGPAADRAPGLPSAGGRYLVTGGLGGIAHDVAGYLVAAHGARLLLVGRSPAD-----GERA-DRLAALRAL--GDV
EYRQLDVADTAALTAAIAAAEARWGRGLDGVLHLAGADPRHTVARETPEGFAAHYRAKVAGTLAVADVLETRPDAHLVLFGSVNGEFGGHSFGAYSAANA
FLAGFADHWHHERHRPVHCLSWSMWTGTGMNRGRSAA-AAVSRGFRVIDPADGLQLFLDAVASPHHRLAVGPDPSNPAVMDELVPDRLRAGE--AVVAYT
AEGV--APE---TVRAAAAAGLRRCPVPIRLVEVTAVPKRADGNVDTAALLRDAPGRPRRA-FTAPVGEREEKLAALWSQALDGARVGRDTSFFDLGGNS
IRATRLLALVEDAFAVRVGTQELYEHPTLAAMAEAIGRR-----------
>tr|F8C9S6|F8C9S6_MYXFH Putative non-ribosomal peptide synthetase OS=Myxococcus fulvus (strain ATCC BAA-855 / HW-1) GN=LILAB_00720 PE=4 SV=1
PCLAVARWVPRPLASSVSKTQGAVVVIADEAFAGAMRE----QMR-REVV--------------RVAPEASGDLVHVLGALAERGLPCGDVVVRLPDVGG
EAPADAEARRVVLAASVAPLLRALQA------AVRVLAVLPETGTGTHGA-GTQAALLAPGLLWAAAAEVPGLEARVTWAPSDA---S-AAAHAAAREVT
SQDAAREVAWRDGTRWERLFTPWTPPPLA--APQRLKREGLYLVTGALGGLGREWARQLRQGVDARLLLVGRRAHGPE----------ARALEAEL-GAA
KYLSVDVTDEAALREAVRHAEAHFGQPCDGAFHFAGTLTPTPVADETPESFVQGAAAHALGALSIAAVLEGRPQAVCVFAASLMGTLGAGRHAAYCAGTA
FLERLAERLTA-QGRHAAAVSLSQVRETGLARALGT----APPGYRVLEPSQALASVALAGEHAPAHLLVGVVASAWPWRQAGLGSGRYLDA--AHVFLV
PP-P-------------R---PEGLS-GAVLHPLTEWPRRADSSVDREALAAD-LSGTG---DGTPAGPFETVVMEAFREVLGAQGVGAGSDFFTLGGSS
LQATRVVARINERTGLRLREVALFEHPTATALADHVRRV-----------
>tr|Q1DBW8|Q1DBW8_MYXXD Putative non-ribosomal peptide synthetase OS=Myxococcus xanthus (strain DK 1622) GN=MXAN_1603 PE=4 SV=1
PCLAVSRWVPRPLATRV-GTRGAVVVIADEAFAGALRE----QAD-YEVV--------------RVAPEASGELVRAIEALAERSVPCGDVVVLLPEAQE
VPAVSDAVPQAAVASRMAPLLHALQSRG---EGVRVLAVLPESGGD--DA-ASLAALLTPGLLWTAAAEVPGLEARVAWTPPDA---S-ATAHAVARELA
SQDAAREVAWREGTRWERVFTPWTPPPLA--APQRLKRGGLYLVTGALGGLGREWARQLRQGLDARLLLVGRRPHGPE----------ARALESEL-GTA
KYVSVDVTNEVALRNAVRDAEAHFGQSLDGAFHFAGTLTPVALEHETPETLVQGAAAHALGARAIATVLKDRPQAVCVFAASLMGTLGAGRHAAYCAGTA
FLERFAERLTA-QGRHAVAVSLSQVRETGLARSLGA----APPGYRVLEPSQALASVALAVEHMPAHLLSGVVGAAWPWRQAGLGEGQGLDA--AHVFLV
QR-P--G--------DVP---PEGLS-DAVLHSLPEWPCRADGAVDREALAAD-LSGAG---DGAAAGPFETVVMDAFHEVLGAQGVGVGSDFFTLGGSS
LQATRVVARINERTGLQLREVALFEHPTATALAEHVRRV-----------
>tr|A0A084SW96|A0A084SW96_9DELT Peptide synthetase OS=Cystobacter violaceus Cb vi76 GN=Q664_14145 PE=4 SV=1
RCLAVPRLVPRPQVPAGVSLSETVLLFSPSGFATALKE----TISPVEWV--------------ALAPD--ANPLHTLETLEAQSLRFEDVVYVMGR---
----ASRAGSAELARSISPLLRLVQGRA---AAVRLWVVAPRAEGSSF----DAAPLLVPGLLWSAKADAPNLSVRLLWVPSET---P-DAAAFVAGELQ
GLRSAREVSFHDGQRWERGFTPWVPSRLE--GAQRLRREGLYLVTGALGGIGQAWARHLKHSLGARLVLVGRRARDAA----------AEALEREL-GA-
TYAQVDVTDSARLRAVLDEAESRHGRPFDGVFHFAGNFEPVPLEAEAPETFIQHAAAHVLGALALAEAFQPRPEALLFFASSVMGTVGWY-ATSYCAATG
FIDRFVEHLAA-RGRRAVAVSLGPVKATGMARTLRA----SPVGSRTLEPQQVLAALVLALESGRTHVLVGVDGSAPAWRTAGLGAGEPLEQ--AHVFFT
QASP--G--------VLP---VKGEPGVTALHPRPAFPRRPDGQVDAEALAA---ESFG---EGVPTGPLEEMLVEAFREVLGVEAVGTHSDFFSLGGSS
LQATRVMARIQERLGLRLRESVLFDQPSVSRLAAHLQEL-----------
>tr|D7BUR9|D7BUR9_STRBB AMP-dependent synthetase and ligase OS=Streptomyces bingchenggensis (strain BCW-1) GN=SBI_00139 PE=4 SV=1
PWFFAPVWEEAPLRGAAPPAPNPLVVFADDHQDGLLTGATAARMPPVIVVRPGPYGLREQADGYRLDPEDEAGYRALLTAIAREHPQVDGIVHAWSLAGD
A---VPGGL----RRGALSVARLV--AD---SPAALLVATRLPVAAPTAA-GSLANGALTGLVRSVATERGEGVTRLIDVADNA---GRALITAIRAELA
S-SGETLTRYAAGRRLAARLQPIAAPALSR-PGEAFHEGALYAITGGSGGIGQEIAHHLAAAYGAKVLLLGRRDAAET-----PA-PSPLPPEGK--GEI
RYERADVTDPDALGDAVARAEQTWRQPLAGVLHLAGRSLAHVVAREPSEEYEQTLAPKTAGTLAAAHLLDDRPDACLLLFSSVNGYFGGTGFGAYAAASS
FQDAFAAYWSRSRGRDVRSLAWSQWSGVGMNADGPMTAAAAARGFRPITPAQGLGSLLLACTGAERHLLIGLDAHNPDISPLLADTATRR-A--VLLGYT
GGRA--ED------VLTAAAGVTGGGVPVHVASVPALPHTPAGEIDGTALARLAIGSGDPSRTRPPKAGLETDIARVVCDVLGRGFIGREESFFEVGGNS
LFAARLQHEVARRLERRLPLRALYRHPTVRALATALREQ-----------
>tr|A0A080NS94|A0A080NS94_DELAC AMP-binding enzyme family protein OS=Delftia acidovorans GN=DR66_1988 PE=4 SV=1
AWFARPVWRPRQHDALPAMAHALTALCGAGAALA-----------QLQALQPRHRWMAL-----DDTGSPADAVAA-----L-REWAPDVLVLAGE----
----------QALAP---GLLQAA-RAP---GGGRLLVCAGTAQD-------EGQRAMARAVLRSLEAEMPALRCRHVAWGDAG---VALDAAGLCAELG
CSQREPEVLWHAGVRRVRRLVPLVPLVPLVAGHQGFQEQGLYLLAGGLGGVGFLLARHLLGRYRARLLIVGRAPAVE------RR-QPLELLSRS--GTL
LYVQADVTDPAALQAAVAQAQQHFGQPLAGVVQLAAESRLALCAEEEEQCFARAQRAKVEGTRHLHALIAHDPRALFLVAGSVMGLLGGRRVAAYAAGDA
WQMAFVERQAHSGGARCRYLGFSAWRDIGLSRQVSNPALFAASGYLSIDEAQGLQAFELAVRGEQPVMTVGLDLGHPRHAAVREGAIYGADE--LVWVRE
GAVD--ARRAGPSAPHRWLHDACGRPVSVPVLNVASLPTDARGELDRAALLR---LAAGMASSAAPRNAFERYMVRLWCKALGLADCGVDDDFFSLGGNS
LGAAQIAARTRELFRVDISMAELLRHPCMADFCQRVIAL-----------
>tr|J2USJ4|J2USJ4_9BURK Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II OS=Herbaspirillum sp. CF444 GN=PMI16_00407 PE=4 SV=1
HWFSEPFWKACPIAVTAGEVHGQSAVLGDASGDAAIR--------ALARAAGDIDWRQFV---LEEQPDPLPSLGRLFNAMA-QQGLPDVILILPG----
----------WARLP---RLLSLCQATA---RGVRLIVCGGADAA-------E--HAAAAAFLRTAAAEIDGVHCMHIQFSGKD---LG-----ILGDLR
QPTRETELAYIDGARHLRRWRNVE----LSADRPALRSGGLHLISGGLGGVGLLLARHLLDRHDAKLLIVGRTEAAQLD--AARA-TALRELERS--GRV
LYVSADVADAAALGAAVAQARARWQCGLDGVLHLAGEGRQTELRRETAATLAQMMHAKVAGSLALQALADAHPGARLVLVGSVAGMVAGRQDAAYAAANA
WQAALAEQL-AAGNTRCHYLGFSSWRHTGMSKNGAPVSTVEAAGYFSLEPEHAVASFDIALSASRPVLAIGLDLQHPRHAGLQDAAIAVDEA--LVVEAG
-------GA---AQGAVMLRDHFGRSLPVAVLAVDAIPRNEAGGVDREQLTR---IAGGFLQLGRPDSEFERYMAQLWKQILDLSICGVHDDFFALGGNS
LRAAQIAAATRERFRLNAAMPDLLQNPTVAGFCAHVQRS-----------
>tr|D6B3W6|D6B3W6_9ACTN Actinomycin synthetase II (Fragment) OS=Streptomyces albus J1074 GN=SSHG_00057 PE=4 SV=1
DWFLHPLWRPAENLHAA-TPAGHRLVLAGPAAVAEEVAGAVRDAGLCTVVTEGPAPERNGAAAYRVRPGEAGDLAAVLERLEADGRTPDTVVHLAATEDA
E--------DGAAPGSDVSLLVLAQART---GGVDLLFVTAGAQATPEER-PTASHAAAGALLKSLREELPWLRGVHLDLSGGS---AGDRAAAVLAEAA
GFPADTEVARREGLRYVRRLAPLPDSAPRT-APAPAPADGFHLVSGGLGGVGSEVAAHLLKEPGTRLLLIGRTGLPPEDPASSRI-EAFRRLRGL--GEV
RYETADVTDAAQVRAAVRRAADAWGVPLVSVLHLAGAFDERPVRELTPQEWREALAAKVDGAWALHRVAAGHPVTSFVTFSSVNGFFGGAMNAAYSAANA
ALDDLALRRRRE-GLPGQSLAWSMWRERGMSLGYQLTSLTEARGYRVLDAQAALRSFDLARTLDLPHLLIGADRTAPWVRSHVLAPVRQVRR--TAARVV
LD------------EGTDLGALYGAAARA------------AGPEGTFVLRSASSGRSEDTGGADELRRLESELAAVWCTVLGRDRVGRDENFFDLGGNS
LLLVAAQTAVNKALGCELGVVDLFSRPTVRALARHLSQQ-----------
>tr|A0A060Q371|A0A060Q371_9NOCA Putative non-ribosomal peptide synthetase/polyketide synthase OS=Nocardia brasiliensis PE=4 SV=1
DCVYVTEWRSVPPSPRHVTLRGPIVLFADESGVAEEFT---RQVPSYLLVRRGATFRR-TEDGYVIDPDLDEHWAAVRSAL----GTPQTVVYLWSIAAE
ID---------------KHLVSAIQCCT---HDPRLITVSRGARVIGTES-GIVAAAATAAVTAVYRQEYPGSEAVHIDLAESA---PERTARDLAIALD
HSTAYPELAWRQGRPYVPALTRVDAPITE---PRPLRANGRYLVLGGAGGIGTELVRNLAATSRAQFLILGRRALDAPN-NTALQ-ANWRKLWDAS-AQA
DYAAVDLRDEAAVRAAVAAAENRWGAPLDGVIHLAGEYRLRALRAERSADWDLTAAGHIRGLLVAAALVRERPGSRLIIGSSLMGEFPAAGCAAYAATNA
LSRALTAELRRRDGTPITRLAWSLWRETGVNAGNRYEAAAAARGFLALRPDDAVRLTAETLCRPPGDYQIGIDRRGTDVRALVDDARDLAL--------T
--------------------EPAGTAPQADLAPVA-----VA-TL--GHM------IRA------------------LDG-FTGLPLSAHTPLSALGRTS
VQMVQVHARLEGALDTAIPHEMFFAATTLGALAGALHES-----------
>tr|A0A0E3JHU8|A0A0E3JHU8_9BACT NRPS/PKS hybrid protein OS=uncultured bacterium AB_162 PE=4 SV=1
ECVYELGWEAVSPVAARSG--APRVVVMDGLGLGDSLSRLWPE--GVERVRPGSDGSRNPAGELVIDPSDPGGWSLMLDSAL-DATGDNVLVYLPTYGSG
APGE-------ALDPGCSHFLALCR-AS---RATRLVVASRAARRAEPVA-EDPGMAPVAAFLMAVSAEVPGLDGCLVDLEGGS---LDSDVQALFEICN
GEWPGPELAWHDGAPHVRLLRSVVLETAD--AEPPFCDGGFYLVSGGLGGVGSELLAELQERWDLDLLVIGRTPLSAAEGESSRR-RALEKLGSAG-GTV
EYRVADVAERDQVEALVADAERRLGRSIDGALHLAGEYDGRLLADEPAGVHAAAFRSKAAGARVLGEVCAARPGSVFVAFTSAFGHVATLGGAFYAAANR
YVDAYAAHLRQVRGISAYSLSWGMWRGTGMAAGGDSEAWLERRGMIGLAPEEARHLALAALHGPPGHLIVGFDGATSLAPARIASRRSTNLE--TVSLEV
PQR----SS---GWSPPPLEDDFGRVVPVALAELQDD---RASRGDDRL---------A---TGEAADRLREVISTAVGEVT-GTPLDEDRPFYDAGLDS
LTILRIHNRIEERLGIEFERSALFEHPSVRSLAGFLTTQ-----------
>tr|A0A0E3M0J9|A0A0E3M0J9_9BACT NRPS/PKS hybrid protein OS=uncultured bacterium NM_1663 PE=4 SV=1
ECAYELAWEPVSSLSARTG--EPRVVVMDDAGLGGALSSLLPG--ETERVLPGRRGSRGPGGELVFDPTDPSAWTSMLDMAL-GASGSNLVVYLPAYGVT
GPAN--GTGSESIDRRCRDLLALCR-AG---RAIRLVVATRAARSIDLVA-EDCSVASAAALLMAVSAEVAGLDGCFVDLEGRS---IDADARALCDTCS
SGWPGPELAWQAGVPYVRCFRSVTLDSAG--AEPPFRDGAFYVVSGGLGGVGSELLAELQERWHLNLLVIGRTPLSADGGASSRR-RAFERLGGGG-GSV
EYQVADITDAARVEAIVEDAERRLGRSIDGALHLAGEYEGRLLADQPVSTGEAVFRSKAVGARVLGEICAARPGSVFVAFTSTFGYVETLGGAHYAAANR
FVDAYAAHLRLTRGVPAYSLSWGQWRGTGMAVDGAGEAWLGRRGIISLSPTEARHLAVAVLRRPPGHYIVGLDGAHSTTPARIVSDRPTNLE--TVSVVV
PAL----PA---DWTPPPLEDDFGSAVPVALAEPDEH---HASDSGERN---------LDSDVSSANARLGEVIREIIGQVT-SQRLDDDRAFYEAGLDS
ITILRVHNRLEEQLGIEFERGVLFEYSTVRSLAAYLAAH-----------
>tr|A0A0M0SSN3|A0A0M0SSN3_9CYAN AMP-dependent synthetase OS=Hapalosiphon sp. MRB220 GN=AMR41_05690 PE=4 SV=1
DWFYRKIWRLKQAATYT-NYTGLYLVFLDRLGLGKSICRELNRRNPYITVEAGLQFFKLNRDSYCINPNEPEHYEHLLESLKADDFCIAQILHLWTYDDY
AG--SLEALEDAQQQGIYSLLFLIQAIQ---GSVELQVISSYAQFSPGDK-IAYEKSTLIGFLKTVPLELSWLRCRHIDLEIQP---VEVNAEHIQRELS
VAGSDAEIAYRNGRRLSSSLAKVDMLDQQT-QDIPLKQGGIYLVTGGLGGIGTYLCQFLIKEYNAKLITVGRTELPDRTRLSKRI-KSYLSIEAVG-GEF
IYKAVDICNLDGLLDVVTQAESIWNEQLSGIIHLAGEENDHWVTVETQKTFDSMLRPKVHGTWTLYQLIKNNPQAVFISFSSVNSVFGGATFSAYSAANS
FLDCCSVYQRYHLHQQTYCFNWAQWDNLGMSQGNPERDAALGMGYYIISKEQGLSSLLAALYRNQAHLIIGLDGSNRNIQRYTDSKSYSIQN--LTAYFT
ASND--SSKA--SFTELIVRDRFGTKSTCNFVGLQQMPLTDTGEIDREQLKTKSQERSGASKWVAPRTEIERQLASIWQQLLSVPQIGIHDNFFELGGHS
LLATQLISRVQDMFQLELPLRSLFENPTVAQLSSVIVQR-----------
>tr|D8G898|D8G898_9CYAN HctE OS=[Oscillatoria] sp. PCC 6506 GN=OSCI_3900012 PE=4 SV=1
DWFYRPIWRPKVAIPAT-TITGATLIFLDSIGLGTYLNVELENRNPCIKVAIGDEFTKIDTNHYKINPKHAEHYLQLLASLLEDKIAIVRILHLWTYQAY
LG--NLEALEESLDLGVYSLLFLTQSLK---AAVQLQVISSYSQPSPDDK-IASEKAPILGLVKTIAQEIVGLKCRHIDLPIDS---VAVNAPYILTEIQ
TDSNDSEVAYRNGQRLIPRLEKVYLTIAEK-QKLPFQAGGMYLLTGGLGGIGVEIAKYLLETYQARLLLVGRTQLPPRSVVAQKI-GAYLALEKLG-GEI
IYEAVDICDFTQLQQVVNQAQSLWQCKLQGVIHSAGIYQEGLLVKETKDSFAKTLHPKVFGTWVLHQLILKHPNPLFISFSSVSSFFGGAMVGAYSAANH
FLDCFAHYQKYQCSIESYCFNWSTWNEVGMSQGYRGKDALHARGYKSMSAKEGLHSFLTGLYNDRANLLIGLDGSKSFIQQYTEVTEAVKHP--LNL---
---------------------------ECES--------------P-KS--------QRKKTATTAKTEVEKTIASIWKQVLNIDDLDIHDSFFDLGGNS
LLVAQVTGKLQEFLQRDISMSEMFQYPTISSIAKHLDSP-----------
>tr|M1MGY2|M1MGY2_9CLOT Polyketide synthase PksJ OS=Clostridium saccharoperbutylacetonicum N1-4(HMT) GN=pksJ3 PE=4 SV=1
NYILTKEWVRKEIQYK-QLSNICV-INNDKN-IDELF----------EKN--NVSFKS-------------------IDNIA-D-AQENDILLDFFFYDE
NDL--SQNLSYVLDKASTHIKDIMKI-------LTIIFPTKQSINESDMT-FRINNGFINGLLKTVCLENPFLRCRIVDFDK-------LNISLLVNELN
LSIKDEVAVYRDSKRYIPCLKTANKGN-C--NEAIIQYDSLVLVVGGLGGIGIHVSKYLINKYNSKLLIIGSSDLEKN------I-DRYNKLINIS-EDV
IYCKADVTNYQEILDSVNKAEHQFEIKLSTIVNLSGKMSDHTLENEEFKNMLDSSSVKLLGTYNLEKIRKSKEDASMIVFCSLTGNFGGISMGAYSLANT
LQENYCQSLIN-LGERVFCINWSMWSKTGLNKYSNSSS-AVFGGFNELDIDQGIGYLNFIIENNIKSSYVGINRDCLKMRYQVHDFYDMSLI--INLDDK
NK-----QKVKNYS-------NLTSRLVC--------------KIDKS----------RFN-SDANISELQNKLMMIWKDNLKVEEIHINDNIFDLGGNS
LTIFKIVEIISYEFNMNIKPIDIMIYPNIYQLSTYLYSK-----------
>tr|E6UAT1|E6UAT1_RUMA7 AMP-dependent synthetase and ligase OS=Ruminococcus albus (strain ATCC 27210 / DSM 20455 / JCM 14654 / NCDO 2250 / 7) GN=Rumal_
KPLMTRIWQEKPCTHEAE--QDCTLLVGTIR------GSIHSLIENYTKVLP--------FSKYDTLPADT--HVSVI--------------MDFG--QD
SD--------------IHTKITILQDEE---YGVVLNVFTSGGFYKPGDS-VN-ENAVFNGILQSYQMENGNIFVKQIDVAEGD---ML-----PGAEEI
TQTNDHVIVYRSGVRYVPYLVSADVDTSV---TQPITEGGLYLVTGITGGVGRKITSFLARNYNCRFIAVGRKSEEAA------R-EIFRSEQMDE-SVL
AYRNIELSDTDQLSSFVADAEQMDGSTLAGILHFAGSVSLHFLVSETMGSFDEALAPKGYAVSSLCKLLEGRPDCRMLLLSSVNAFFGGSSLAAYSGANS
FLNEMALSCME-KHPQVYCINFANLSNIGMSADIPDKESSKKNGFYLLTLEEAASVMLYVLAHHIRFSFYGINLQNRNMQQFCCEPMQ---Q--RIIAYL
PKEP--GQIS--SILGNTAELRFGRLADYEIQSLHRMPQLEA-WKD-TLRSR--GLFASASRLLQPSTETEQAIYNIWKEVLQIEDFGIDKSYFTIGGNS
LNSFRTLEKMNRHFNTELTIADFFTYNSVQEFAELLDQR-----------
>tr|W4LZU6|W4LZU6_9DELT Uncharacterized protein OS=Candidatus Entotheonella sp. TSY1 GN=ETSY1_00090 PE=4 SV=1
SWFYRPIWRRQNAVRHT-DHRGTYLIFMDRIGLGDHVGKLLAKRHACVRVETGTDFAQLSPHHYCMDPVNPSHYRRLLDDLATKQVRPDHILHLWTYSKS
TG--SLELLEQAQELGLYSLLCLIQAIN---QAVRLQVISSDVQYSSGEK-VACEKAPLLGLLKTISQEISWLTCHHIDLSVDR---NEINSAHLLQELC
VLQKDQEVAYRDGYRWVPRLQNVDFHHEAP-HDIPFKPGGMYLLSGGLGGIGVELARHLLQHYQARLLLVGRTPMPDMLSVVQHL-QAYQELKRLG-GEV
MYRAVDLADKLRLQQAVSQAKSRWGCELDGVIHLAGIFQPRLIMEETRTSLAASLRAKMLGTWSLYQLIKDQPHGVFIAFSSVNGFFGGATASAYAAASC
FLESFMACQQRHRYPQSYCFSWSMWDEVGMSRDYQMKSLSRAKGYHAITAEQGLSSFLLGLRYHQTHLLVGLDGGNPHIRRHCETLSPGMQT--LRAYCT
VKND--VSIS--NLQDVEVLDRFQVPCPCDVLQLQEMPLTPDLNIDRHALSVLAASPGGEADYVPPRTSTEETLVAIWCEVLKLDRIGIHDNFFALGGHS
LIATQVISRIRRAFRVELSLPNLFESPTVASLAERIDAL-----------
>tr|Q3MCQ4|Q3MCQ4_ANAVT AMP-dependent synthetase and ligase OS=Anabaena variabilis (strain ATCC 29413 / PCC 7937) GN=Ava_1609 PE=4 SV=1
DWFYRQVWQPKNPITFNSSLTNCTLVFLDAFGLGTYLCQILSERNQYITVSPGEDFRKINHSHYTITPGQAKDYKLLLKSLATDNITIGQILHLWNYDQY
LG--SIEALEAAQEKGIYSLLFLVQAVQ---GVIQLLFISSYVQSSSDDP-IAYEKSPVLGLLKTIPQELPCLNCRHIDLPFAE---VEKTGTYLLQEMQ
VSSKEREVAYRNGQRFIPRLEKVDFTSKPK-SPISFKHRGTYLITGGLGGIGIEIARYLLKHYQARLLLVGRTPLIHH-VITQHQ-KAYQELSQLG-GEV
IYEAVDICDLNHLQIIVEKAQSQWCKNLDGVLHLAGTSHEQMILEETQENLAAILRPKVFGAWTLHQLVKDNKGSIFINFSSVNGFFGSTAVGAYAAANS
FLDGFSHYQNSHSELTSYCLSWSMWHEIGMSQGYQLKNLIRTKGFYVMSSSQAISSMLATLQHQQTHLLIGLDGSNQNIQLWQS-QAFNLQK--LSAYFT
THSD--DIF---KLQHLTVEDRFGNSCNCNLVKLKEIPLTESGAIDKNKLIRQ-FTGQDTGTHVAPRNKLEQQIADIWEQVLGRPVFSVHHNFFELGGNS
LVGTQVISRLRNTFSIDLSLQSLFKLPTVAELASNIEVI-----------
>tr|A0A0M4SRC4|A0A0M4SRC4_9NOSO AMP-dependent synthetase OS=Nostoc piscinale CENA21 GN=ACX27_12195 PE=4 SV=1
NWFYRQVWQPKSSIAFNSNVTNSTLVFLDSCGLGQYLCQILSENNPYITVSPREDFRKINRSHYTITPGQAKDYQLLLESLAADNIIIGQILHLWTYEQY
IG--SSDALEQAQEHGIYSLLFLTQAVQ---GAVQLLFISSNTQSSVDDS-IAYEKSAVLGLLKTIPQELPWLNCRHIDLPVAK---VETNGAFILQEIQ
VSSKEREVAYRNGQRFIPRLEQVDFTSQPK-SSISFKQGGTYLITGGLGGIGIEIARYLLQHHQAKLLLVGRTPLTLE----KSI-KIYQELEPLG-GEV
IYEAVDICDLQHLQIIVAEVQSKWGKNLDGILHLAGAFHEQLVVDETQESLISILYPKVLGSWTLHQLIKDNHGSIFINFSSAHGFFGSTAVGAYAAANS
FLDCFSHYQNTHSELASYCFSWSMWDDTGMSQGYQMKNLIRAKGFYIMSSSQAISSMLTGLQHQQTNLLIGLDGSNQNIQRWQS-QFFNLQK--LTAYFT
AS----NEV---KLLDLQVQDRFGTSCTCNLVQLNEMPCLENGEIDRTSLMRK-INSQEIKERIEPRNEIEYKIAQCWQQVLKVPLLGIYDNFFELGGNS
LLAGQVIARLREDFSLELSLQRLFQTPTIAGLAQAIEAI-----------
>tr|U5QGL8|U5QGL8_9CYAN AMP-dependent synthetase and ligase OS=Gloeobacter kilaueensis JS1 GN=GKIL_1830 PE=4 SV=1
DWFYSKQWRQRVLE--VSDPKGAVLVFVDDSGLGSILKPHL----ECVQVEAGEGFQKLGKGHYRLNPTSVEQYGQLLGSVESEGLHLRHILHLWGCRPY
RQ--A-SDLLRAQETGLQSVLALVQAMH---DGLALRVVTNHLQALPGDP-IDCAGSTVLGLLRSLDQELPWLDCRHIDLPVEE---GEHCRDALLAELV
SGRGEREVAYRQGRRWVARLQKVDMVAQVK-QPVPFQKGGFYLLTGGLSGIGRSVAKQLLSQYQARLLFVQPTIEKE------QR-EALAALMDSG-AEV
IAREIDLTNLCGLQEAVEGAKQRWGRHLDGVLHLEQPYRESLVVEETPEQLARFLYPQLQTSWTLHQLLAGQPVGFFLRIAHASGELGGIVAAGFAAAQS
FASAFVQYQRQAGLQNSYCFSFGFWEDFEPGRDYPWRPLAAARGYRFLSRREGWHSLLAALAQGTPSLVAGIDGRSPAVRPYCLDDLHPLEQ--LTAYYS
GE-----IL---PSTLQAIPDRFGRASSCNCMRVKAIPRQLNGQVEEQALIAQSHSRRESVTQAAPQEQVARTIAAVWQQVLQVDRVGLDDSFFDLGGHS
ILLVQVQQQLQQVLGRQIALLDLFTYPTVGTLAQFLKQG-----------
>tr|R7I2Q0|R7I2Q0_9CLOT AMP-dependent synthetase and ligase OS=Clostridium sp. CAG:411 GN=BN648_00257 PE=4 SV=1
QYVLRKTMTEIKNSLQDTKVNNCI-VDTSF--LDKPF----------FTT--TIESKQ-------------------I-----------AEVYDYIF---
-------------QN----VRKYLQT-------QKVVFPVL----YQKEQ-FSWYRGILPALFRTLAMENTNFHFKLLFLEE-------NENDLIERECN
SLDGYDVVYYSNGKRYIETYETYNAVCKRE-NAAAFMDNKLVVLVGGFGGIGRLLSKYLLENYRNIRLLILGRKKKED------V-KELL-ALYPK-EQV
LYGTADVTRYEQLDEVIEQAKQEVGREIGCIFNLTARGITHAIEKKREDLYTESAVVKLLGLKNIECVR-MKNNCKMYVLGSVTADFGMVNMSAYAVSNL
LAEEYCSHLPQ---EQVVFIGSSGWNNIGMNLKKNSEDTSKSGFLEGFTAETGIRMLDNILTSGVGSCFAGINHEFKGLQYCITDPFEENLQ--LVVTSE
EQ-----ELVKKYS-------LCQKKITV--------------RIDPL----------RQVRQRDNTEGIEQEIKHIWEEYLAKDIKSFDDNLFDIGGNS
LTVFQITEAVNQIFALQLNPIDIMTHSTIRSFSLLIREL-----------
>tr|A4F3K2|A4F3K2_PLAAG Non-ribosomal peptide synthetase/polyketide synthase hybrid enzyme OS=Planktothrix agardhii NIVA-CYA 126 GN=aerA PE=4 SV=1
DWFYRKVWKSKSPVNLK-SSNNYTLIFLDQLGLGEFLAAQIKVKNPFVTVLAGEEFSKLSGDRYTIKPGEAEHYQHLMESLAEQKITIGNIIHLWTYQEY
QG--RIEQLEQAQEQGIYSLLFLVQAIH---DLIQLLFVSSHSQCTSIDE-IAYEKSPVLGLIKTLAQEIPWLNSRHLDLPIDK---NEINGAYLLQELY
VLSKEREIAYREGNRFISGLEKVNLPEQLK-QELPFKSGGIYIITGGLGGIGIQVAQYLLKNYQARLLLIGKTALPEKHEFSLKI-KNIQALEHLG-GEV
IYQAVDVANFTQVQQAVDEVKQHWKGELDGVIHLAGIYKNCLLLDETKQGLAAILRPKVLGTWILHQLLKESQGGIFISFSSLASFFGWAALGSYAAANT
FLEHLNNYQKSKHLFPSYCYSWTTWQETGMSKGYQMQYLTRSQGYYDMTVQQGLDSFLASLYHNQGQLMIGLDGSNSKIKRSTS-LSEGLQK--LTAYYI
PKPP--NPIH--LGDHLILKDRFGTPYNCSLIPRQSLPLKDQGEIDKQQLIKE-LQGQENREWIAPRTEAEGKVAQIWQNVLNLPQIGIHDNFFELGGHS
LLASQVISRLRDVFSVELSLHSLLEYPTVASLTQTLEVL-----------
>tr|L8NZJ3|L8NZJ3_MICAE AMP-binding enzyme family protein OS=Microcystis aeruginosa DIANCHI905 GN=aerA PE=4 SV=1
DWFYQKVWKPRSPVNLK-PSKYCSLIFLDSLGLGASLAEKIQGQNPCITVLAAEEFSQISQNCYTLRPGTANHYQQLMASLSERKIILGNIIHLGTYQDY
QG--TIEQLEKAQERGIYDLLFLVQGIH---DFIQLLFVSSYSQFIETDE-IAYEKSPVLGLIKTLAQELSWLNTRHVDLPLDQ---TEINLSYLLQELS
VLSKEREIAYRNGKRLIAGLEKVNLLQHTQ-QELPFKSGGIYLITGGLGGIGIQIAQYLLKNYQARLLLIGKTPLPEKHQLSLKI-KNLQALENLG-GEV
IYQAVDVANLPQVKQTVEQVKKQWQGELNGVIHLAGIYKDCLLLDETQDGLSTILRPKVIGTWVLHQLLKESQG-IFISFSSLASFFGGAALGSYAAANS
FLESLNTYQKSKNLFPSYCYSWTTWQETGMSQGYQMQYITRSQGYYDMTVRQGLDSFITSLYHNQRQLMIGLDGSNSKINRFTS-GSEGCQK--LTAYYT
RKTV--QSVN--LPNHVSLKDRFGTSYQCPLVLRQSLPIKDNGDIDKRQLLRE-LQGKENNELIAPRTEAERQVANIWQKVLNLSQIGIHDNFFELGGHS
LLASQVISRLRDVFSVELSLHSLLEYPTVASLTQTIEVL-----------
>tr|F4XJ07|F4XJ07_9CYAN Acyl-CoA synthetase/AMP-acid ligase II OS=Moorea producens 3L GN=LYNGBM3L_04630 PE=4 SV=1
DWFYRKVWHRKEAVTLRTPTNGRTLIFLDSLGLGEVLCSKLGK-DQCVAVEPGAPDAQLTGNRYSIDPTNPDHYQQLLKSLVETDQPIPQILHLWTYDEY
RGEESSEALEQAQNQGTYSLLFLIQALDGLKSQLNLTVVSSYTQPTSPQDDIAYEKSPILGLIKTCPRELPWLNCRHIDIPVDD---HHINGFHILREMA
VCQKEREVAYRNRNRLVPLLEKADLPQLEKQ-ELPFKQKGMYLISGGLGGIGVEIAKFLLNHYQAPLLLVGRTPLPEPSTKFAPAYQNLEQLAEQLGGEI
RYEAVDICDLAQLQQVVERAQSDWQANLQGVIHLAGIAPEHFLVEETRNSFAATLRPKLLGSWVLHQLIKDKPDSVFISLSSVLAFFGGATIGAYAAANN
FLECFCYYQRHKTLVRSYCYGSSTWVETTLNRSKQIRESRRALGQYGIFNQQGINSILAGLHHDQHSLILGLDGSNPYVRRYTQQPPYHRQRVSVYFTAV
TELSVAQLQRL------EAFVPFGTSITPKFKQLQAMPLTPAGEIDREQLIS----PSKDTENVLPVTDIERQLASIWQKVLGVSQIGIDDNFFGLGGNS
LLAVQLSGEIEKTFGKQLPLAALFQAPTIKQLAHLLCQS-----------
>tr|U9VTY0|U9VTY0_9CYAN Uncharacterized protein OS=Leptolyngbya sp. Heron Island J GN=N836_08730 PE=4 SV=1
DWFYEKVWVAKSAHGEAQSVTGLTLILADSSGLGQALQEKLASSDACLLVEAGAEFSQLTAEGYTLNPHNPQHYEQLWAALSKRDQPITQIVHCWQYGEL
LSG-SLEELVTTQDLGLYSVLWLVQTLASQPDHATLQIVASNAQATHDQESVAYEKSPLLGLVKTISKEIPWLDCRHLDLAIAP---IQENVTYIVDELQ
VLQQEREVAVRDGLRRVPRLQPVGFNDEPAQ-DIPIQPGGFYIISGGLGGVAVEIAQYLMRHYQAHLLLLGRSPLPERSEWTAERLL---LLEAIDCDRI
QYSAIDICEFDQLLKVVEQLKSQWQVPLNGIFHLAGTAPERLLLQESQASLADTLRPKMQGTWSLHQLAMGQESCLFVSLSSVISLFGGATVGGYAVANS
FLESFSQYQRCEAGLQSYCFGSSTWSQIGVNKGYQGTDARRAQGQMAMSVHQGLDSLLIGLTHRKYQLIFGLDGTKRPVQCLKNVPVALTHRFQAYGTLA
IGHPTNHLAPT------IVDERFDTPSHCEFTVLPELPLTVTGELDREQLSTI--VAAKNPGQTAPRNPVEQELVQIWQTVLDVDSIGIDDNFFELGGTS
VLAARLFLQIEQSFGRVLPLATLFQSPTIEQLAQVLAQS-----------
>tr|K9X829|K9X829_9NOST Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II OS=Cylindrospermum stagnale PCC 7417 GN=Cylst_6440 PE=4 SV=1
DWFYQKIWRRKEILHSPEISAGFYLLFLDSSGLGESLGAKLNQ--PWIGVEMGTSFAKLSANRYCINPQNPADYQQLLDSLSQEMKHISQILHLWTYKEY
VEESSLEMLEKAQVSGVWSLLFLVQALAKTHNKVNLMVVSTQSQGIDAKDLIAYENTPLLGLLKTIPHEIPWLSCRHVDLQIDP---VNINRELVLRELK
AVTKEPEITYRQETRWIPRLKKIDVTQNFPE-KIPFRQGGMYVITGGLGGIGKKLATYLLKNFQARLLLLGRTSLPPQNEWIAERFQTLK----QLGGEI
CYETLDVCDLHNLDQVVQKAQSLWQCSLDGVIHLAGIFQERLLIEETQETFAQVMYPKVLGTWSLYQLIKNKPDALFITSSSVNGFFGGAMVGAYAAANR
FQEHFSHNQISRNIKQSYCFNWSQWDEVGISRGYSMKILSRNRGYLSISDQQGLESFLIGLCYSSFPLWIGLSGKNPYIRGYLESKPENVEQLVAYVVNK
ISLPEKHLSEL------VLSDCFGTLSISSVVELKEMPLTATGVIDYQSLVARIGFSSKSGKLIQPNNEMENQIAQIWKNILGFSEISIHDSIFAIGGSS
LKMIQIHHQLEDSLGQKFSITEMFQYPTIHTLAKHLAQF-----------
>tr|B3PCU3|B3PCU3_CELJU Putative BarE protein OS=Cellvibrio japonicus (strain Ueda107) GN=CJA_3004 PE=4 SV=1
NWFFTDKWVLAPVAKSAVATRNDLVFFTDRHNAQTLL-QAAGTSVFCI--VPGAECERLSEKLWAVRPGQDEDFYQVLLQITAESSG-YDVINLWPLYSD
THS---------------------QVLPGTLNSLKYLLVEQ-----FDSQLFSADVEMASGLLRTARYELPGLTTRCLKIEADH---FNRLLNLILQEVN
STGHEDSVAFLGQQRLKKSLECLHVTQEKL--LPALRRDGTYLITGGLGGIGFEVAQSLVRTVGCQLILIGRSAADAAPVR-----SKMAQLQGMANARV
DYHAVDVTDPLQVQALFASI-----PALDGVIHMAALYEANTIEQESMESIAKQARVKLHAAQHLALCQEKNSTGLFISFSSIFGYFGAATLGAYTAVNS
ALEAFSRHLHSHSQLRSLCIAWSNWDDIGMSRGYKNS---DAKGFLALTARQGFQSLLIALEVNEPVVYIGLDETKNYVAREIVGDCVATSQVAIYYESS
MGEPHVDLC-----------DYRGNKIPVIYKPTNGLPRRNDGSVDVDALNL----STPMARSVRAANFTEKQLRGIWAEILDADHFSLEDNFFEVGGSS
ILVPTLVKVISETFAKPYTAVEFFKYPCIAEAARYLDAL-----------
>tr|A0A0R3IUS4|A0A0R3IUS4_9MYCO Peptide synthetase (Fragment) OS=Mycobacterium sp. H110 GN=AOT93_27775 PE=4 SV=1
NWFFRPVWHRRDRLRPA-PIDGAVLILGESGDLGAQLADRLTAQVRVVRATVADVTTAIRTVVYLAAPRAPGDIADS-----------------------
--------SPEPLPVGVFDVVRIVRTVFDEERGDGLYVVGSGIEQVTDTDEADPGLAPIPVLLRSAVAEMPGLRVRFVDLDRTD---QTAGADHVAGELG
YSTKDIEVAYRDGARWVKGLER--LPDEPTV-GVAIPSGGLHLISGGLGGLAYELARLLIERFGVRVLLVGHRDPDERQS-----YQRLRDI--AGDEAV
RFEVADVRDADQVWDAVTSAEDRWGIQLSGIWHLAGAYREQPLATTTESDLTDISTAKVAGARVLHHIALRRPGIRFVSFSSVNGFFGGSTVGGYSAANA
YLDAFTLYQRRS-GISAHSIAWTMWDRVGMSAQVEHLEGTRASGYRVVGRVEALNSLLVALAHDVPHVLVGLDDTKSAIRARLSGVAPTGQVLVA-----
------DLK-------------------QTAPEFPDMPVRDR----YDRIVPTRQSAGVARQWVAARGDTERRVSAIWRQVLGSDSFGVTDSFFDIGGNS
VLLALAQRLVQEEFGRPIALVDLFRYPTVSSLAAYLSSS-----------
>tr|A9AYS6|A9AYS6_HERA2 AMP-dependent synthetase and ligase OS=Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785) GN=Haur_2414 PE=4 SV=1
RWFFSKQWQPVSKRHNSALLKPSYAIFSDDTTLARELIDVLEQHHDWVLISAGETFSQQG-QHYTINLHDPEHYHQIAATLAATN--IHDYVHLYSCDLP
SEIEHVGDLAAAQYRGTYSLLFLTQALAKQKLSASLTVVSQRSHANQSDQV-IYAAAPIHGLLKTMPLEIDWLSCQHVDLDAASAT---TNSQQIYYELA
QPKPSAEVAYRAGQRLVPQLVEAAQSSPV---ESPLVKGGLYLVTGGLGGIGSQFARWLLQNYNARLLITGSTELPLGSDWALGTDSSLSKRLIDISNDV
HYQAVDITDSAQLARLINDAEQRWNQPLAGVFHFAGAGNLAWITNESLATFEMMFAPKVYGTWALQRALSQRPELPIVAMSSINSFFGGATFSAYSAANS
FLDSFMLHQRQTSHPKALCLNWTQWDNIGMSLNNQIRSLSAERGYNVIGLQQGLQSLLAGISQNQYPLMIGLNADSPALRQHLAVSQPLQQNLYTTHQHG
PDRYR------------QLANSYFGSATLEWYRVAELPRTSSGAIDLAAL-GQLDATNQQTALDQPTNIIEEQLVSIWQEILGKPKIGIHDNFFALGGHS
LLATQLVSRLRDGFNLEVRLYQLFAAPTIAELANCIAEL-----------
>tr|I3TWS9|I3TWS9_TISMK DidF OS=Tistrella mobilis (strain KA081020-065) GN=didF PE=4 SV=1
--LARPVWRPAALR-RPDPATRAVIHQ-----------------------------SDGGDA---VAA--------------------------------
--------IAALRDR--------LAPLLTEGSGLRL--GVRGLEADPGDPTPEPATAALAAWAASLAQETARLELRVVDLDPGADAA--AREAELAEEAG
HADPEPVVARRGSRRLARRLEPLDLPAPR---VLPITAGGIWLLAGGTGGLGVELAELLGRRFGARLLLVSRSDATADPMKAL----------SAAGVEH
LAMTADVTDRAALDAAIHAARSHWGAPLAGIVQMATDGALDGGLADSDAALAATIGPKLEGTRNLVAIARDHGDLPLIGFGTVNALFGAPTLGAYSAANA
AMAAVLAGERTAATGPVTTIDWSMWDGLGLAQGAPARARTRALGYRIIGRSQGLRALLAALALDRPRVVAGVDAGSPVMRRPRAAPPRPL-----LVPVT
RGSVI------------NATDRFGRRVTIGTG-----------------A-AAPAGPG---VADPPRGPVETRIAALWCELLERPAIGRHENFFEIGGHS
LLLARLRARMVPLAGREIGIVELFRHPTIRDLARLVAAD-----------
>tr|U5QGL0|U5QGL0_9CYAN Amino acid adenylation domain-containing protein OS=Gloeobacter kilaueensis JS1 GN=GKIL_1820 PE=4 SV=1
DWFYSKQWRQRVLEVSDKEPKGAVLVFVDDSGLGQSLR----PELECVQVEAGEGFQKLGKGHYRLNPTSVEQYGQLLGSVESEGLHLRHILHLWTYQER
QVLESAQAVEAAQQKGLYSVLALVQALAARHDGTALRVVSSGAQALPGEEP-AWEQGGLTGLLKTVGQELPWLDCRHIDLPLEEGE---RCRDGLLAELV
SGRGEREVAYRQGRRWVARLQKVVARVKQ---PVPLRKGGFYLLTGGLGGIGLEVAKHLLTRYQARLLLVGRAEAKAD-------------RLENLGGAV
LYRQADVCDLQAMEAAVEGAGSHWQGALDGIFHLAGAYNE-LLVEQSVVSLQEVLRPKLTGSWVLHQLLRKRPEALFVGFASVVGYFGAATLGAYAAANS
AQEAFAAYQRANGYGQSYCTSWSIWDDIGMSQNNRQ--TLQARGFQAIPAHQGVHSLLAALSSGESHLLIGLDDSRAAIRLHLENPDRQLLNACLTRPFG
GIRTL------------RLPDRFRQPSRCEATQLAALPRTADGRIDREKL-RTLGRAGRVAERIAPRNDLERQLARLWQEVLNVPEPGIADSFFALGGSS
LMLTQLVSRIRDHFRVDLPLQILFGTPTLAGMAKLILAR-----------
>tr|A7IE19|A7IE19_XANP2 AMP-dependent synthetase and ligase OS=Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2) GN=Xaut_1011 PE=4 SV=1
AWFHAESWVRRDLDAEPVPP-RGVVFLGGPDGLAAALAQALEREGPV--VSAGAD-VDGGLQ---VALA---------------DARADTVVDLRPLA--
-PVPAGETLDDFRARAGLELAATLALLQQLGRGPPLTLVTRGG--AGSGEGIDPVRAALRGLLRTAAQEMPGLACRQIDVGGLDATA-PDLMARLAREIR
APAGEAEVALRPTGRFVPRLEPVGRPREP---ALRLKTGGRYLITGGTGGIGRALASHLAARCRARLLVVGRSAGGSEED----------------GPDL
LTRAVDVTDADALEAAIRVAEEHFGGPLDGAFHLAGISPAG-LAQETAEGLAAAFAPKAVGARVVIEAMARRPGGFVVLWSSVNAIFGGAEAGAYAAANA
ALAGM-----VGEGTRVLCLNWSRWQDLGMSAPAGAAEFAAARGFRTLPVEDALASLEAALALGTSPLSIGLDGASPFVRARVRQPARPLQLAGFVVPRP
GPAND------------DLADRFGTPIPCPLRVLDAMPRSADGTIDTEAL-SRHEGVA---AVESGQDGVEAELAAIWSVLLKRSSIAPDDNFFTSGGHS
LVAAGLVHRVRAAFGVDLPLRILFEAPTLRGMARWIAAN-----------
>tr|F7NDS7|F7NDS7_9FIRM Lichenysin synthetase A OS=Acetonema longum DSM 6540 GN=ALO_00920 PE=4 SV=1
QWLYEPVWRPQENGREAVNGQGIWLIFAHRSGIGERAKRLAERGERAVVVYPGESFACLEKDIFCSSPSRQDMNRLFQETLHSGRDCCRGILHTWSAGAG
RKEISAADLEQAQELGCLHVLQLVQAVRECSGMFNRPRLWLVTKGSQPVLAVDVAQAPLWGLGRTLALEQQELWGGLVDLDAA--APDEQAADRLIADLL
VHDGEDQVAYRQGRRYIARLQR-HIPSGKRDISFRCAANGSYLITGGLGDLGMQVARWLVQQGAKWLILMARTELPPRSAGYITNIKELEAM----GASV
YLAAVDVGDERQFKAFLTRYREEYWPPVRGVVHAAGTVADALLTACEPAAFRAVLRPKVQGAWHLHHLLQDDPLDFFILFSSISTLVSSPRLGSYAAANA
FLDALAH-QRRQLGLPALSINWGPWADIGMAARSQKTA-LTAAGTNPIPPAAGLQ------------ILEALAGRDL-EQVAVMD---M-DWEQWGAIFQ
QAGKAGLFEDLLQEIAATVSSAASGEGSVRA------------GL-------------LGAGPEERRQLLEQYLCGQTAQVLKLPRLDVNAALNGMGLDS
IMAVELKNKLERTLGVVVPMVNFLQGPSIAELAAQVQEL-----------
>tr|A0A0D3V7R8|A0A0D3V7R8_9BACL Uncharacterized protein OS=Paenibacillus sp. IHBB 10380 GN=UB51_07420 PE=4 SV=1
DWMYRMQWNKKNLLTTKRSVSGTTVIFSDSCGLVEELSHEWDRN-NFIQVQVGQRFEKLNENVFRMNPKLLEDYCLFSE-LTNKGVIINEIIHLWNYDEV
WMVTNVDALREAQFLGSYSLLFLAKALSRYAPDHSI-RFTVVASRLHGVLEVSFEKSTLVGILKTMEHELTDFSFKLVDV-----YPSENAAQTVRNEFF
NYDDNHIVAFRNGERYVPVLKK-INPLHSSRKPLPFVKGGLYLITGGLGGIGKQVAAHLLDNYNAKLLIIGRTPLPERRYERIQHLLELESQAK-DGAFV
AYHATDLCDANKLKQIINDVEQSENTRFSGVIHLAGILHEERLADASVEKLEEMYEAKVYGTFVLTQLLKGQKEALFVSSSSVTTLSAPMMLGAYCSANT
FLETFSSFQRQTLNMDSRCFSWSLWDGIGMSRETAFTG-ATTSGYLHITNKLGMFSLLSGLKTGHSQIYVGLDGTHPNQKLSVTK---SRNQTVFHAFFK
VE--TGVNEHSVLSINKTQLKAVL--SSNNG------------NV-------------LYA---EPRTSTEQVLVGIWSKLLKVGRIGVLDNFFVLGGHS
LKAIQLFSIVRQSFGVDISFKELFSQPTIEGLAYHIDQA-----------
>tr|Q6E7J8|Q6E7J8_9CYAN JamL OS=Lyngbya majuscula PE=4 SV=1
NWFYEINWQTQPLPSTNGNQTGNWLVFALTSELTECGKELAQKGHNCIWVSPGSEYQQLDAQHYQINPTVAEQSQLLQD-----NADIKGIVHLWGVDET
KE--SVGELAKAQELGCATALHLVQGLTQAGLTQVV-PMWLVTQGTQTVLVVQPQQGSLWGLGRVMRLEHPELTCCRVDLDPK--SPVADTLPILVDELL
FNNQEDQIAIRQGVRYVARLVQ-QQPSTEVAEQKSIQAEASYLITGGLGALGLEVAQWMVKEGARNIVLTGRSAPKEAA----KTIRELE--T--AGASV
NVLLGDVSTQEDVTKIFQQMVEASLPPLKGVIHAAGVLDDGVLQKMSWERFTKVMAPKVSGTWYLHQLTQDLPLDFFVCFSSMASMLGNYGQGNYAAANG
FMDAIAHY-RRGQGLPGLSINWGAWATAGMAARLAREH-QNMQSSVAIDPESGMQALGSLLSGSQSQ-------------VGVFP-------VNWPEFFR
QMP--GMAKLPFFSVEQSQKDR------ILE------------QL-------------NVASDREQEKLLTSYLQSRVAHFMGMTQIELEKSLTVMGLDS
LMAVELRNQIQTELAVDIPATRFMEGITIIALATEIKQQ-----------
>tr|K9WBM1|K9WBM1_9CYAN Polyketide synthase family protein OS=Microcoleus sp. PCC 7113 GN=Mic7113_1753 PE=4 SV=1
--------------------KSCWLVFVDECGIGSQIARIENEGQDVISVRVGEQFDQVSEWEYTINPQRKEDYHSLLKKLDFLDKIPSTVIHSWSITSH
EQIPGVELFEEAQHLGFYSLLFLTQALSKQTIPLRLWVLSNSMYAVESTDVSYPEKITLLGLCKVIPQEYSNITCQSVDLVLPKLGSKDKLIDQLLAEIT
GKSSDLVIAYRANQRWRQVFEPVRFDNPVES-PKQLRQGGVYLITGGLGGFGLTLAKYLVQTVQAKLVLTGRSALPPKEEWVSTRIRKIQE-LEDLGADV
LVISADVANEIHMRRVITQTEKR-FGKLNGVIHAAAILDDKSILDTSYTESNWHFQAKVYGLYTLDKVLQDREDFCILMSSMGAIF-GGTGFASYTAANL
FMDAWVHRQNQLGNSNWCSVNWFHYEDAFLALRGIAPDP----RKIEVFHEQVVEIFKRLLSNRIPQVIWQSDIETE-----V-----------------
--------DKLIKH----KSSQ-------Y--PEKVKSEATPSLYPRS----NL-----RTTYVVPSSEIEHRIAQLFQEFLGIDKVGIHDNFFELGGNS
LIATKMFLIIRQELQVEIPLISLFQKPSVAELALFIEEI-----------
>tr|C6WBZ9|C6WBZ9_ACTMD KR domain protein OS=Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971) GN=Amir_3682 PE=4 SV=1
--------------------GETCLLLSEGPL-GREVARLEDLGVHAVFAPVDP-----------DGRADQHRYRELLADLTARDRTPRLIVHLRPFEAA
-GADDLDAVREGQITGLHSLLHLAQAIGAGSEPVRLVAVTRGAQAVLG-DLAHPEHATVASAVKVIPRELPRVSATAIDVDAGSA----GLADRIVAELL
---SPTEVAYRGPQRFERD--YHPL-PLG----RAPEPGGVYLICGGLGGIGLSVAEHLAP--TARLVLTRRTPFPGSGAD--VLADRLAA-LTAGGAEV
LVRQADVADETRMREVLAEAESR-FGPVTGVVHAAGAPDA---QRRSRHDTDDAMASKVLGPVVLDTILGDRPAFFVLCSSIGSVLHLKFGEVGYVAGND
FLDAFAAHRASRRPGLTVSIAWTDWRDEGMWGTV-H--PKLDDLLGAISRSEGTELFARILAGNP-RVVCALDLGALLA--RH-----------------
--------EAFST---------ED----HRA---A-VLRIARSRRDRS----AL-----SSAYREPGTATERGVADCWATLLGDDPIGADDNFFELGGDS
LVALRLLAVVRERYGVELSMAQ-FEGPTISDLAAAVERG-----------
>tr|A4KUB0|A4KUB0_STRHI TlmVIII OS=Streptoalloteichus hindustanus GN=tlmVIII PE=4 SV=1
--------------------AGRCLLFSSG-PLGHAVERLVAAGVDV---------ERVADPAICFDPDRPEHYRELVA---GRGGAPRLVVHLWALEDA
LARGPSGLMPEVQRRGLHSLLHLARALGAAGGPTRLVAVTGGAQEVLGDDLRHPEHATALAAVKIIPREYPGMACTAVDLDLTRLDDLDWLAERVVDELL
AARESTVVAYRGRRRFRLDHAPCPLEPGDPA--VGPRPGGVYLVCGGLGGIGLNLAEDLGR-LPAKVVLTHRRPFPAAEDWTSVAINRLRG-IIEAGGEV
LVAPADLTDSDAVRAVVAEAERR-FGPLTGAVHAAGVPDAGVIHRRTTADTEAAIAAKVHGTAVLDEVLGDRPDFFVLCSSIGSVLHLKFGEVGYVAGND
YLNAYAAYRAARRPGITTAIAWTDWLESGMSAVAQERLVDRAGDLLGATRDEGVEVFRRVLRAGGPQVVSTQDLDAL-----L-----------------
--------ARHDAY----TTGDHL----A------VVGLSAHGGRSRA----RL-----STAYAAPRSDLERTLAGWYAELLGYDQIGRDDDFFELGGDS
LLALRLRSMVRSGYGVEVSVAQLFDAPTVTGLATLVGHA-----------
>tr|M3C9I4|M3C9I4_STRMB Beta-ketoacyl synthase OS=Streptomyces mobaraensis NBRC 13819 = DSM 40847 GN=H340_10245 PE=4 SV=1
--------------------TGGCLLLGDGDT-AKAVARLEALGVPVTTV--GG-----------GRPPGPERYRELVGP------ATRLAVDLWPLRDA
SHRGGAAGVRTAQDAALHNLLHLARAFGALRHPARVVTVTTGAHDVLGDDLAHPEHATVPAAAKVIPREYPWIACTALDVEPGLD----RLADLIVRELG
---ETTVTACRGRRRFTPCPVRQPL-PAA----PAVRPGGVYLVCGGLGGIGLHLAEYLGR--ARTVVLTHRRPFPAPGAWPEAVVRRLRS-LAATGATV
VVRRADLTDHDAMRALADEVEQA-HGPVRGVVHAAGVPDA---QRRDRAGTDAALAAKLTGTLVLDEVFAHRDDFLVLCSSIGTVLHLKFGEVGYVAGNE
FLDAYAAHRAARRPGRTLSIAWTDWRE-GMWAAA-Q--RRLGDLLGAISPEEGVDVFARLLAADP-NVVSAQDLDELLA--RH-----------------
--------AAYTT---------DD----HLA---A-LLRIAAA-RDRS----AP-----AAPYAAPHTPAQRRIAGWYRDLLGVEHVGLDDDFFALGGDS
LLALRLLSQLRDAYGVEISVAR-FDEPTVAALAAATGPP-----------
>tr|A0A081BVS0|A0A081BVS0_9BACT JamP protein OS=bacterium UASB270 GN=U27_03387 PE=4 SV=1
--------------------RQQWLVFLNECGLNSKIVQLQQHHQEVFIVKAGSSFSKMTDHEYTLNMRQPEDYNLLFNDLQSMNVRLNKIVHLWNVTGN
EREQILERLDISQNRGLHSFLSLAKAIGNHSDEIALLVVSNNMQEVTGDELLYPEKATLLGAVKIIPQEYQAVRCRSIDIVLPESGQEAKLVEQLLRDFT
TPSEDIIVAYRGNYRWKQTFEPLRLEHARKE-HTRLRDRGVYLITGGLGGIGLVLAEHLAQKARVKLVLTGRSAFPAKEEQISQKIRKIQA-IEATGSEV
AVFSADAANLEQMAEVVAQTEKQ-FGQIHGIIHCAGIP-YKVIQRRSREDTEEILAPKVKGTLILEHLSQHTRDFFIVCSTIGAILHMKFGQVGYSAANE
FLDAFTYYKTSRDGTFNVSINWNDWKEVGMSERAEQRWVASAVRHGIMLPSEGAEVFDRILEQSAPRIVSTQDLPTL-----I-----------------
--------VKDAEA----A---AT----F-L-ETPQTSKAAKSTDARP----EL-----STTYTEPGNTIEQELVELWQQFLGIEPIGIYDDFFELGGDS
LLGTQIMARSRETFNVDIPMGRLFEDPTIAGIAAYIAKN-----------
>tr|V5UVT2|V5UVT2_SORCE Polyketide synthase OS=Sorangium cellulosum GN=mscG PE=4 SV=1
--------------------DQRWLVFLDRSGWGEALAQLRAGGGEVVVVRPGDVFQGEGGRDFVVDPASAEQHRQLAGALDQGAGVPRRVVHLLGIGRA
ADGD-------EQLTAFAGLASLIAALGRRDPAIELTVVSRGAQSVTGDEDLDPGSAALPALVRAAEQEHAWLTCRSVDVSDRELG--AWLADRLIAEAL
SSSPAQLVAYRGKHRWEPTFEPLATGPDGQ--AGGLRQGGRYLVVGGLGGAGLGIALHLAGAFAAQLLLVEDPDVPAPAD------------PR--AASV
QVIRARIDDPGELSRAVREAEAR-LGGIDGVVYAAGVDD-AGIGDLRVADVVSRLAHHGRAIPALESALAGRSDFCAVSSSLSAILG-GRGLGAYAACSL
LRDAHVRRQ--RSAQRWVAVNWDRWLDGARREGREVFHAEGAGPSQGLEPEQALRALERILASPLDQVVCSGDLAAR-----L-----------------
--------AQGRRA----EPDAAP----A-R-RAE-GAGAPADGDDRP----DL-----STRYVAPRDEPEEAIAEVWRELLGMTRIGVEDDFFELGGHS
LLATRFLVRLEERLGTQLTIADFFQRPTIAALAARARET-----------
>tr|V5UWF6|V5UWF6_9DELT Polyketide synthase OS=Jahnella sp. MSr9139 GN=mscG PE=4 SV=1
--------------------DRRWLVFLDRAGWGEALVALRSARDEVVVVRAGAAFEGQAQGGFVVDPSIPEHHRRLVEALDQGAGVPGRIVHLAGLDRT
PGDA-------ERLAAFVSLASLIGALGRR--PLSLTVVSNSAEAVTGEEDLAPGGAALRALARAAGQEHATLTCRSVDVSERELG--PWLVERLIAEAR
SISPEPLVAYRGRHRWVASFDPIPIGGNDE--VGRLRQGGRYLVVGGLGGVGLAIARHLAGARAAKLLLLEEPGVQQPVE------------PAPGAVAI
EVIRARLDDPGELSRCVREAEER-LGGLDGVVYAAAIDD-GAVGDLRTPDVVSRMARHERALPALEAALAGRRDFCLIGSSLSAILG-GRGLAAYAACHL
LRDAFVRQQ--RTAQPWITVNWDRWLDGPRRE-------AA-GEPLGLDPAQALRALERILDDPLDQVVCSGDLAAR-----L-----------------
--------DQARRV----EIDAAP----P-A-QRAGEALPPAEAGDRP----DL-----PTPYVPPRDEIEEATAAIWRELLGITDIGAEDNFFELGGHS
LLATRFLVRLEEQLGVQLKIADFFGHPTVAELAALVRDA-----------
>tr|D9T855|D9T855_MICAI Beta-ketoacyl synthase OS=Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442) GN=Mica
--------------------PGPLLLFAAGER-GTALARLRERGVDVTVVRPGPAFA--RPDGYRLRPASVADHQRLLDECADD-GRAARIVHAWALDGD
PA--DADAVAAAQEHGYLALLTLLEALP--AVDVTLDVVTAGTADVTGSDLLRPEHATVAGVVRSVPLERQGLRCHWVDADPAEPG---AD-ELL--GAE
---EAVALRLGGRRW-TRGFAAA-P-ARR----PAVRDGGRYLITGGLGRIGGAFAAELAR--RGALVLVGRTARP-----------LVEA-LERAGAQV
RHVRADVTDVDALRAVRADIEDD-LGGLDGIVHAARLPDG---TGSRPAEATAELLPKVTGALALRAVFGDMPDFVLLSSSVTALAG--LGRADDTAANA
FLDAYARSPH-GWRSPVLSVAWGAWREEGVPDHD-GLAPDAVR-----------AACRVLAEGRS-VAGAY-TVEAVAGHLAA-----------------
---------------------------------------------TTA----AT-----ASTVTAADGDLQDTVARIWRDVLGVTEVGPHDDFFRLGGTS
LVAAQLVLRIRQAVGARLSMRV-FDAPTVAAMAARIESL-----------
>tr|A0A0N0B226|A0A0N0B226_9ACTN Short-chain dehydrogenase OS=Streptomyces sp. NRRL F-7442 GN=ADL09_17650 PE=4 SV=1
--------------------HGPWWVIADGGP-GLEAALLTAAGAEVVCGTGRGPG---------------SGYAGLLA----GGPRPRTVLHALLPGRD
T------DDATAQRLGFHSVRALAGALSEDPGPVTLLLCTSGAVEATGGDLRHPGQATLAGLRPVLGQEFGDLTCRLADTDRTTRG--------LLREAV
---SAEPVALRGTDRWVRGFAPVRLGPVP----PVIRPGSTVLITGGLGTVGTALAERLAR--RSCLVLVGRTPLPPEQDWRTEAIAAVRR-LRALGAEV
LTTAADVADRDAMATALAAARER-FGAIDVVIHAAGTQGR-FAPTLGAEVCELHFRSKAGGLRVLDTLLAADEPLRITLSSLAAVLG--VGYGAYAAANA
AMDAYARA-----GGRWLPVNFDTWNLGDPHGDL-G--FT--MKDFHYDADEGFDVLERCLAVSVRQVVS-------TGPGRL-----------------
--------GQWTQ---------PA----GGA-----TTGPGRVRHPRP----DL-----MVGYEPPASPEEAALAEIWGEILGVDGVGVHDSFFDLGGHS
LTAVRMMARVRSRFG-GFPVAA-LENPTVRSFSAVINGR-----------
>tr|F8JL88|F8JL88_STREN Beta-ketoacyl synthase OS=Streptomyces cattleya (strain ATCC 35852 / DSM 46488 / JCM 4925 / NBRC 14057 / NRRL 8057) GN=SCATT_p1
--------------------HGPWWVLADAGP-GAEAATLARAGAEVVRLTS--GD---------------RGYAEVLA----AGPRPRTVVHALLPGRE
T------DDAGALREGFHSVRALAGALAEDPGPVTLLLCTSGAVEATGGDLRHPEQATLVGLRPVLGQEFGDLTCRLADTTAATRG--------LLREAV
---GAEPVALRGADRWVRGFDPIRPPASP----PVIRPGSTVLITGGLGTVGTALAERLAR--RACLVLLGRTPVPPEAAWRAAAIAAVRR-LRALGAEV
LTVAADIADRTAVAEALTAARER-FGTIDVVIHAAGTQGR-FAPSLTDDVCDLHFRSKAGGLRVLDELLGADEPLRIAVSSLAAVLG--VGYGAYAAANA
AMDAHARA-----SGRWLPVDFDTWNLGDPHGDL-G--AT--MKDFHYDADEGFEVLQRCLALTVRQVVS-------TGSSRL-----------------
--------DQWTA---------PG----AGP-----DPGATRTRHPRP----EL-----MTGYEPPATPQEAALAEIWGDILGVDGVGVHDSFFDLGGHS
LTAVRMMAKVRGRFG-GFPVAV-LENPTVRSFCAVINGR-----------
>tr|A0A093SIM1|A0A093SIM1_PECCC Polyketide synthase type I OS=Pectobacterium carotovorum subsp. carotovorum GN=KP17_08370 PE=4 SV=1
-----------------------ILMFHHDDSFSGQFS-LIQQGASLLHVVAGEKYA--GDDHYRIEPGNEMHMKLLIQDLAETAMLPDWVVHLWCLGNQ
DET-----TDRIQSQGLYTMVAWCKAYNELTVNFHTLLVADRMISIVGEEDIEPAKSTLLGISQVLPKEYQDIQCHLVDIAPNFQA---QTIRMLLAEMG
---SSSEIAIRGVHRFVKDYARYSVSETQL---SLLSGNKTILIVGGLGNFGLELAEFVALNYQAQVYLTTRTRFPARSEWVSEKILHLQR-IEDLGGRV
EILTADITCLQDLVQINTLLQTR-HRRVDGVIHAAGTVD--MIHTKTRDSLEQVFSPKIAGTMNLCDVFLPLNDFILLCSSMNAIIG--LGQVDNTAANA
FVDAWAEHCHQRGYTQVLAINWGAVNEARARNY-SAQP-QFEHIKNKMSQDEIFEVYRRLFS-TGSRVVSTLDFNKV-----I-----------------
--------ENWSRV----GSVASLT-QKV---T---------SRSRDE----FV-----QTSWKDPLSTYEITVAKHWEALLGIDRVGNDDNFFELGGNS
LIVLQLISLLKKDYPIKMHAMA-YEHPTVREFAAHVEQL-----------
>tr|E5B8A6|E5B8A6_ERWAM Beta-ketoacyl synthase OS=Erwinia amylovora ATCC BAA-2158 GN=EAIL5_2891 PE=4 SV=1
-----------------------VLMFHHHDQFSSLFS-LIRQGATLLQVSTGEKYA--AEDHYQVVPGDEKQIAQLINNMSENKILPDWVVHLWLLGNR
DAT-----TDSIQSQGLYTMVAMCKAYSQLPVDFHTLLVADRMVSIVGEEEIEPVKSTLLGISQVLPKEYQDIQCHLVDISPDFQP---QIALRLLAEMG
---VSSEIAVRGAHRFVKDYARYTLPAAQL---SLLAGDKTILIIGGLGNFGLELAEFVALNYQARVYLTTRTRFPARSAWVSEKIRCLQR-IERLNGKI
EILTADITCREDILRINTLLRDR-HERIDGVIHAAGTVD--MIHTKTRDSLEQVFAPKITGTINLCEVFLPFNDFILLCSSMNSIIG--LGQIDNTAANA
FVDAWAEHCHQRGYPQVLAINWGAVNEARSRNY-SALP-QFEHIKNKMSQEEIFEVYRRLFA-SGSRVVSTLDFNQV-----I-----------------
--------ENWSRV----GSVASLM-QKV---T---------PRSRDE----FV-----QTAWSEPTTEYEASVARHWGVLLGIEQVGNDDNFFELGGNS
LIVLQLIGFLKEDYPIRMHAMA-YEHPTVREFAAHVEQL-----------
>tr|C5AG73|C5AG73_BURGB TubD protein OS=Burkholderia glumae (strain BGR1) GN=bglu_1g16910 PE=4 SV=1
------------------------AD-----------------AARCTYVVPGTGFAA----TFAIDPAREDDYRQLLDALAAGAGLPRYVVHAWLTPEA
DWDG-PARFAEHQTPGLFSLIYLARTLNLATGSCSVLVAASQLVALP-GEALHPDKATVLGISRTLQKEYAFIDCRIVDVAARELF-ASPSAARLGL---
-LAANEIVALRHGRRWQSVYERFAVPAE-----PQVAAEGLYVVFGGLGELGLSVADYLASRAACTILLLNSSRFVPREQWPYRKIERIRA-MERRGATV
CIERCDITDAQALGATLDAARAR-HGAIHSVIHAAGRVENGMIDNKDIAHFDTVFAAKVYGTYHLLAYLRP--TKLILCSSMNSIIG--LGQIDNAAANA
FVDAIAQTGL-AAELGVCSTNWGAVNAERLTRPN-----VLHMR-NHMTEQEIAAVYDRILHWNGPRLIS-TDFDSV-----L-----------------
--------EHWGEV----SKVTELARAQE-----AGT---------RAG----E-----DDGQV-YRSDLHRFVERSWAAILGA-RLGWDDVLLEQGAHS
LSAVQFVSMIKDRYQI--GLMIIYEIRTLGLLVEHIEAK-----------
>tr|A0A096YVV4|A0A096YVV4_BURTA 3-beta hydroxysteroid dehydrogenase/isomerase family protein OS=Burkholderia thailandensis (strain E264 / ATCC 700388 / DSM 132
------------------------AA-----------------AARCLYVVPGAGFGE----TYCIDPASEGDYQRLIETLAARGRLPRRVVHAWLAAEA
AWDG-PANFANCQTLGLFSLIFFARSLNRVSAACSIVVAASQMAALP-REEVNPDKATVLGISRTLQKEYPFIDCRIVDIASHELF-ATDSAAQLGL---
-LPENEIVVLRGARRWQTTYQRFAVPAK-----PDVQARGVYVIFGGLGELGLNVAAHLASRAPCTLLLVNSKRFVARDEWPYKKIEKIRE-MEKAGATV
LLQQCDVADAKRVDAVLDDARER-HGVIHSVIHAAGRVENGMIDNKDVRHFETVFEAKVYGTYNLLSYLKP--TKVILCSSMNSIIG--LGQIDNAAANA
FVDAVAQTSL-AASLGICSTNWGAVNAERLTRPN-----VLHMR-NHMTEREIAAVYDRILHWNGPRLIS-TDFDSV-----L-----------------
--------EHWGEV----SKVTELARAAE-----AGE-----QASARAP----D-----DDGYA-YRSELHRFVETSWARILGV-HVDWDGVLLELGAHS
LSAVQFVSMVKDRYDV--SLMIIYEIRTLGLLVEHIETK-----------
>tr|A0A0A8FBP2|A0A0A8FBP2_9ENTR Polyketide synthase OS=Dickeya zeae EC1 GN=W909_06750 PE=4 SV=1
--------------------GRGVVIFMDKAGVAERIAQLEQQGARVCRVVAGKPFSRKSPLSWVIDPALPQDLEAFASSLRKQAFPLDHVIMCWPVAR-
RALS--------ATDYYECLLNIARQFTDYQTPLLLHVISNALHVVTPDEQGDPARALLVGPCRVLEKEFEQLTCRSIDIDLPPRPARDHNLAPLMAELT
S-GDDSFVALRGGVRYIQSLEPIVAEPVDEE--LPVMRHGRYLLTGGFGGIGMTIAQWLAQHYQAHVILLGRSDVPPEPQWKSLKIKQLQK-IKQLGGTV
SVIAVDLGNTRQVSQALKAVSRT-QGMIHGVFHCAGIADR-LIQQRTAADSLAVFNAKVQGTLVLERYFRRRPDFFVQCSSLAATVG--MGQVAYCSANA
YQDAWAIA-RQRTHTRYLSVGWDSWQEVGMAVDS-----LKAVIRHGIRPQEGSELMARLLARQESQYISTRGLPLP-----D-----------------
--------ADTTTQ----P---D-------A-QTE--ELETQQLYPRP----PL-----ANAYIEPRDAVETTIARIWQEKMGIGPIGIEDDFFELNGHS
LMAVQIIAQIRQQLAVSFPVGFIYDYPTIAGLAGQVRLR-----------
>tr|W1J808|W1J808_9ENTR Putative Polyketide synthase type I OS=Xenorhabdus cabanillasii JM26 GN=XCR1_2660015 PE=4 SV=1
---------------------------------------------------------------------------------KQQKVRVNNIIHAWSITRS
PSIA---------FTNYESLLHIARQFAVDADILKINILSNRLHAITEHDCNDPAKALLIGPCRVIPKEFEQVQCKSIDIALPATRPSNVIMSTLLAEIL
-QEQNNIVALRGRHRYVPLIETATL--PV----SLFRQRGNYLITGGFGGIGATIAMHLASRYQPHLIFISRSELPPQNEWRSRHIRLLQQ-LQQMGASV
SVIAADLADAARVGKALTDVVLQ-HGQIHGIFHCAGIADG-LIQNRRFEDSLQVFQSKVVGTQVLDNWFKRQPDFFVLCSSLASTVG--MGQVAYCAANA
FEDAYALSRHKKNRTRYLAIGWDSWCEVGMAVDS-L--RQWESIKHGILPEEGCQLLESLLAHSSVYASTRGPLPDI-----D-----------------
--------QGSEEN----TAAGQDPNEGASI--QKSSKTDEQKLYPRP----VL-----NVDYQPPRNQTEEIIADIWQEKMGIGPLGVFDDFFELNGHS
LMAVQIIAKIKQRLQVTFPVGF-YEHSTIEQLAEQVNLR-----------
>tr|A0A0B2U100|A0A0B2U100_9ENTR 6-deoxyerythronolide-B synthase OS=Dickeya solani GN=OI70_01420 PE=4 SV=1
--------------------GRGIVLFMDKTGMAERLAQLEQQGARVCRVTAGKRFSRKNPLNWVIEPNAPQDLAALASSLEKQKFPLDHLILCWPVSR-
RALP--------AIGHYETLLSIARQFAGAQTPLLLHVVSNGLHAVTPTDRCDPARSLLVGPCRVLEKEFEQVVCRSIDIDAPSRVAFDRNLAPLLAELG
A-GDELFVALRGGARYIPSLEQVVAEPADEA--LPVLTHGRYLLTGGFGGIGMTVAQWLAQHYRAHVILLGRGDVPPQSRWKSLKIRQLQK-IQQLGGTV
TVIAADLGNARQVTQALKAVTHA-HGAIHGVFHCAGVADR-LIQQRTPADSLAVFKAKVWGTLVLERYFQRRPDFFVQCSSLAAAVG--MGQVAYCSANA
YQDAWATA-RRRTHTRYLSIGWDSWQEVGMAVDS-----LKAVIRHGIRPQEGCELLARLLVRQAPQYISTRGLPLP-----D-----------------
--------ADTPAE----D---D-------A-PAE--G-QETSLYPRP----PL-----SNAYLAPRDHIEQTIARIWQEKMGLGPIGVDDDFFELNGHS
LMAVQIIAQIKQQLKVAFPVGFIYDYPTIAKLAGQARLR-----------
>tr|S4YPX2|S4YPX2_SERPL 6-deoxyerythronolide-B synthase OS=Serratia plymuthica S13 GN=M621_21785 PE=4 SV=1
--------------------GRTVVLFMDRLGSAKRLAMLENQGARVRRVSKGIRFRILRSGSVTVNPQRPQDFHLLAEYLRSQQQAPDALIHGWSITRS
RALS--------ATLHYESLLHIARHFHPEDAPLDLFVLSNHLHALAGDEQIDPGKALIIGPSRIIPKEFSQIRCKSIDFIPPSRYATTRALSTLLAEMQ
H-DEAPMVALRGAQRYAPLTE-LDCGPQTEP--FSFCNGGNYLITGAFGGIGSTIAENLARRHRARLLFIARGELPPEAEWKSRRIAFLRQ-LQQAGAQV
TVISADLADKRSVGRGIAAFTQR-YGTLNGIFHCAGVADG-LIQNRSADDSQRVFQAKVQGTRVLEACLRQHADFFVVCSSLAAFVG--VGQVAYCAANA
WQDAWALNQRRDARTRYLAIGWDAWRDVGMAVDS-----LRKTLRDAITPKEGWTLLTQLLARNGGHYISTRGLPLV-----D-----------------
--------SDANVQ----T---D-------I-AQPDREGLQPALFPRP----PL-----SSEYLEPRNETERQITAAWQEKMGIGPLGIEDDFFELNGHS
LMAVQIIALIRQRLNVSLPVGFIYDHPTVAALSEQVLMR-----------
>tr|K9EKE9|K9EKE9_9CYAN Polyketide synthase family protein OS=Leptolyngbya sp. PCC 7375 GN=Lepto7375DRAFT_0333 PE=4 SV=1
--------------------EAAWLLFVDDTAHSQAIARLSMA-HVAVTVHPGDSFSRLDQHTFTVNPHRPEDYRALLNGLG--DHRPTEILHGWSLTSA
TD------FNEIQAQGCQSLLYLTQALTQCHHDLRLTVLAANILNVTGTEPLSPGHATILGPCTVIPQEYRQITSRLVDWPVNADSDLNVLLAELAAGSE
EPSVEPTVAYRHGLRWVQRFSPMPLPEAEP---ALLRQQGVYFITGGLGNVGLTLAASLA-PWQAKVALLSRRSLPDREQWICDKIRQIQT-METAGVEV
LILAADVADAAQLGGAIAKTEAR-FGPINGVIHAAGAV-EQMIAETGSAELEQQFQAKVTGLQNLAAALEGKSDFGLLCSSLASVLG-GLGFAAYSAANY
FMDTFAQQRS-QASFPWMSINWDGWRFQPDEHPE-----LGTMADFALTPAEGNAVWQRLFAYAVPQMVSTGDLTAR-----Q-----------------
--------QQWQPA----PA---------------PADEANRPQYDRP----AL-----AGDYQAATTPLEQEVVEIWESFLGIRPIGIDDSFFELGGHS
LLATQIMVHLRQQFQVDIPLRCLFDQPTVAGLARAIVEY-----------
>tr|U9W039|U9W039_9CYAN Polyketide synthase OS=Leptolyngbya sp. Heron Island J GN=N836_21435 PE=4 SV=1
--------------------DQAWLLFVDDTALGQGIVQLTA---TTVTVHTGASFERLDEHTFTVNPHRPEDYRALLNALG--EYRPNEILHGWGLTSA
TE------FDEIQAQGCQSLLYLTQALTQCHHDLRLTVMAANILNVTGTESLSPAHATILGPCTVIPQEYRQITSRMVDWPVDADSDLKVLLAELTAEPD
----EPTVAYRHGMRWVQRFTPMPLPEAEP---ALLRQQGVYFITGGLGNVGLTLAASLA-PWQAKVALLSRRSLPDRSEWICDKIRQIQT-MEAAGLEV
LILAADVADAERLRSAIAQTEAR-FGRLNGVIHAAGAV-EQMIAETGKAELEQQFQAKVTGLQNLAVALEGKSDFGLLCSSLASVLG-GLGFAAYSAANY
FMDAFAQQQSKAASFTWMSINWDGWRFQPDEHPE-----LGTMADFALTPAEGSAVWQRLFAYAVPQMVSTGDLKAR-----Q-----------------
--------QQWQSA----PP---------------MADEANRPQYDRP----AL-----AGDYQAATTPLEQEVVEIWESFLGIRPIGIDDSFFELGGHS
LLATQIMVHLRQQFQVDIPLRCLFDNPTVAGLADAIVQH-----------
>tr|A1TTJ1|A1TTJ1_ACIAC Beta-ketoacyl synthase OS=Acidovorax citrulli (strain AAC00-1) GN=Aave_3732 PE=4 SV=1
--------------------DTVLLLGGAGLPLAERLARLAERRARVVQVAADEGFRRDADGGFGLRPDARGDHAALWRA----LGPVTHAFHFWGLEEA
RGGA----SMAAWQRGYFSLLALAQGRE--DEPLSLTAVIDRAEEVAGSEPLEPGKATVAALARVLGQEMPRIACRVVDVLVPNAG-EAQLADALAGEPA
R-ADEFCVAWRGAQRWVKTYEPAPAPA------RRLRQGSVVLITGGLGSVGLALARHLGRRHGARLVLLGRTPLPPRAEWQRRRLAQLQA-MEADGIEW
MAVAADVTDAAQWRGALQAVHGR-FGGVNGVVHAVMEPGG-MLATRTRAEVEAAFAAKMQGTLAMVDALR--PDFVLLCSSVASWVG--LGRSDYAAANA
WLDAFATARR-DSPWPVFSVNWDAWRDVGVGAGMDVP------EGMGLDERTGMEVFDRVVNGPQPQTVSVTPLAQR-----L-----------------
--------RPLDG-----LV-DAL----E-AQ-----APSGGAAHPRP----VL-----STPYRAPEGELEDNLAALWTEALGIHGIGADDNLFELGGDS
LLAIRLLARVRKAYAVDIHPAA-FKAPRIADLAQLVELR-----------
>tr|H8MFK6|H8MFK6_CORCM Polyketide synthase type I OS=Corallococcus coralloides (strain ATCC 25202 / DSM 2259 / NBRC 100086 / M2) GN=ppsE5 PE=4 SV=1
--------------------ATWWLLLPDDEGLGARLAKLGEAGQDVVRITPAAVTAKHDEHHWSLALGG---EATVLEALTAQGRAPDHVLHLGTLGLG
DAH-GEADFESALGKGFLGLLSLAQALGRQTRPVSLVAVTNRMQA-LGDEAPNPELATVLGPVRVIPQEYGHLSAKAVDVRLPASGQETALVEALLSEAA
TPKLETVIAYRGGARWVQHFEHVPADAPRTA-QLPLRDGGVYLLIGGFGTLGFSHAKSLAKRAKAKLVLAGRTALPERSQWVSRRIRQVRE-LEALGAEV
HTVSVDAGNKVQVKEAVDAALTH-FGALHGVVFAAGDV-QAAIPDTRPEDVRDTFHGRVRGLYALEEAVRGRSDFCVLSSSLAAVLG-GLGLASYSAATS
FMDAFATKQAQTSPVPWMSVGWDAWQYESRAGGAQSP--F---GALAITASEGEDAFEQLFQLGVSHVVSTSNLRAR-----A-----------------
--------RKWAQP----AAAQEK----A----EAKQAGSSLGTTPRP----AL-----QNAYVPPRDELEEKIARLWQTTLGIDQVGVHDNFFELGGNS
LVGVKLIARVREQFGVALPAVTLYEGPTVGALAKLLKAA-----------
>tr|V6MB70|V6MB70_9BACL Polyketide synthase OS=Brevibacillus panacihumi W25 GN=T458_00170 PE=4 SV=1
--------------------SQTWLVLEGEDPWSRLLVRLMEQNQTVISVRKGHAYQVLDENVFVIRPNREEDYAACLQEVAARGLRPDHLLHVWLLEEK
EFQDPYSVFETYVESGFDSLLSLARTWETCTNAVRLTLLSDRLHDVMGNEQIIPEKTVALAAGKVIAQEFPQIQVSAVDLDLRHDSSVDNLADFVIEQCR
SKHREGVVAYRGNRRFVPAYENMEIETSTP---LSLPQLETCLITGGLGDLGLLIAEVLVKQGVHKLALLGRTPVPKRAEWMTEKIRRVQS-LEQMGARV
MVLEADVSSLDQMRQATDEIIEQ-WGSLDGIFHAAGAV-ERFIRETTADLSSQHFVAKVQGLYVLDTLVTQLRTCCILISSLASLLG-GMKSAHYAAANQ
FMDSFSVCSNRAGKTMWASWNLDAFLFGAEKEQVN----LISFSENAMRPHEFALILPALLARIMGRVVSTIDLNQR-----S-----------------
--------QEWVST----GAFAP----------EQAILAHQAALHPRP----SL-----QNPYVAPRNEIEKKICDIWQRTLGIDQVGIQDNFFELGGNS
LVGIKLIAQINEAFSTTLLPVRLYEGPTVQTFAELLGDN-----------
>tr|C6CCJ8|C6CCJ8_DICDC 6-deoxyerythronolide-B synthase OS=Dickeya dadantii (strain Ech703) GN=Dd703_3070 PE=4 SV=1
-----------------------WLIFVQEGEASEWLA-IEQRGQPLIRVYAGDTFS--SAKRYVVAVEEPASYLQLIEHLSSEG--VSHILHGWLFSSK
PVS-----SQHALAQGFYSGLSLLKALAAKGQ-QQVWWITDSVFQVLGHETPVPYSALINGLNRVVTQESGRLICRQLDLCSGDDI---LAVPAIINEVN
---NETLIAFRAGQRWVFAAEPLPLAPVS----ASQTQAGVYIITGGLGQFGLATASYFIRDPQARVILTSRADVGLYHGQETTRLAALEA-LWRKGAQV
DVVQTDAGDEHQVNALLEQTIAR-YGKVTGLVHAAGLIGQ-SFIESDREHCERIFRAKVQGTQILIDALKDIPQFVMFVSSLSPLLG--LGLTAYAAANS
FMDSCATRLNRSQDKHWVSVNWEGWIRQGGVSAD-----YDTFQQLSLSDTEIRLCFERILA-HLSNVVSTGSLTER-----L-----------------
--------QRWSTI----AGMAEIT-GTI---D--------------------E-----SLTLGTRRDDKATVILDMARQLLGNPALGPDDDLFKFGADS
LTAIQLIARIRDLFKVDLPMQT-FDRPTVTSLVCSISAK-----------
>tr|U7QEH2|U7QEH2_9CYAN Short chain dehydrogenase family protein OS=Lyngbya aestuarii BL J GN=M595_4608 PE=4 SV=1
--------------------KKSWLIFIDSLGIGTEIAKLINAGQEVVMVSRGETFDEVGYRTFEINPQEKQDYQALIEDLNLREFHPDYIVHLWGIEDD
K--PSNSSLKTDRNQEFYSLLFLTQAINPGDNTIQVFVVTNPIYNVMGSEEVNPEKATVLGLCLGIGQEYPQLSCRHLDVMVPTAKNHKKLSDCLLAEFI
DEPTELTVAYRDYYRWKRTFKPIRIDANQDK-NIQLRQGGVYLIVGDFSGIGHVLAKYLTENLQAKLILVSSKEIPAYS-------------------YY
LTFKADITNEDAMQAIVEKIDEQ-FGELHGVIYSTPMS-EHLLQQLKPEKCEYGFQEQVKGLLVLEKVLRDKQDFYLLQSSLSSII-GGIGLAAYSAANQ
VIDAFANFKNNQNLANKISTLWYSVNWDAIAYQTEQKT-VTNLAEFTLKPDEVCQVFQRILSLKPTQVVSKGDLDTR-----I-----------------
--------NQWVKF----KPVS-------EKIDNPQTLQSSASGHSRP----NL-----SQEYVAPRDEIEQAIAIILQEVLGIEEVGVNDNFFDLGGHS
LLAIQAISRLRETFQVELPLRNLFETPTVAGIATVIAQN-----------
>tr|Q1D6B7|Q1D6B7_MYXXD Polyketide synthase type I OS=Myxococcus xanthus (strain DK 1622) GN=MXAN_3619 PE=4 SV=1
--------------------PRCWVVFTDGGPLASRLVRLEEAGQYVVTVHAGAAFSRDDERRFTVAPSAPGDYAALLSALEDLTPRPEVFVHLWSLTPQ
GEREILTRFQAAQALGYYSVVHLGQALAGL--PLRVEVISNHLFDPDGRAEALPEKAPLLGPCQVLSQQHVHITARGVDVILP--G-VAALAEQLVAELA
TEARDVRVALRGSRRWVQELSPVRLTETAA--PRPLRERGVYLITGGLGRVGLLLASHLARTKQARLALVGRTPLPPRRLWASLLIRRVRE-LESHGAEV
LVLSADVSKPHWMQEVLAEVDQL-FGALHGVLHCADLPLPPPP-SATNPDAEARFRAKVRGTYVLEDVLRDRADFVMLFSASAAVLS-PFGDTPSTAANL
FVDAFAAHR--SAGTPWMSVAWDPWPRAA----------GAGLEPYAMTENEATEAFQRVVTGGDGPVVATGDVSRR-----L-----------------
--------TAWLQR----AVALP-----K-----------VARK--V------R-----TGDEELPANELERVIAALWQEVLGVEQVARHDHFFELGGHS
LLATQVVGRLRSRLQLDLSLALLFTSPTVAGLAKAIADL-----------
>tr|A0A0F7BM31|A0A0F7BM31_MYXFU Polyketide synthase OS=Myxococcus fulvus 124B02 GN=MFUL124B02_19435 PE=4 SV=1
--------------------RRCWVLFVDGLGVGEALARLEEAGQDVVRVRQGGAFMRDAAKRYALDARLRGDYATLWKDLADQDLSPSVVVHLWSLGSS
GEEPSPELFRKVQDTGYYSLLHLGQALAKG--PVRVEVVTDRVQDVAGEGTALPEKATLLGPCKVIPQEQEHVSTRCLDVVAPAPG-VEKLAERLLAELS
QRSRDAVVAWRGSLRYAQTHSPLRLEPAGE--ATPLREKGVYLITGGLGGVGLMLAEHLARTLHARIALLGRTALPAPSEWVARRILRVRE-LEQAGAQV
MVVHADVADAAQLEAAVAKVEAR-FGALNGVLHCAGVTQPSPLTDIGRSESETQFGPKVHGTYALEQVLSRRSDFVLLFSSNAAVLG-GLGYLTYASSNL
FMDAFAQA--GRSGTRWVSASWDPWPEET----------KHSMDQYAMTPAEGAEAVRRLVTLGDGQVVATGDLAQR-----W-----------------
--------RLWIQR----ETSQP-----V-----A--GARAAGK--PR----RS-----KTPFVAPGSELEKQLAALWQEVLGVDSVGLNDNFFDLGGHS
LLATRVAGRLRTQFDLDIPLAKLFEAATVASLAKLVADH-----------
>tr|L7UAL4|L7UAL4_MYXSD Polyketide synthase type I OS=Myxococcus stipitatus (strain DSM 14675 / JCM 12634 / Mx s8) GN=MYSTI_03594 PE=4 SV=1
-----------------------WVVFVDGLGVGEALC-LEDSGQDVVRIRQGSAFM--AARRYALDPRVRGDYATLWKDLADQELSPSVVVHLWSLGAS
GAG-GPELFRDVQDLGYYSLLHLGQALATGSRPVRLEVVTDRLANVAGESTALPEKATLLGPCKVIPQEQEHVSTRCIDLVAPEPRGVEQLAERLLSELS
---KDAVVAWRGNLRFAQALSPLRLEPSGD---APLREQGVYLITGGLGGVGLMLADHLARTFKARLALLGRTAMPAPTEWMAQRILRVRE-LEKAGAQV
MVVHADVANAEQLEAAVAQVEAR-FGALNGVLHCAGVTHSSPLTDIGRSESETQFGPKVYGTYALEKVLSRRADFVLLFSSNAAVLG--LGYLTYASSNL
FMDAFAQARAGHTGTRWVSASWDPWPEETK---HTNV--RTSMDQYAMTPREGAEAVQRLVT-LDGHVVATGDLAQR-----W-----------------
--------RLWIQR----DTSKPAQ-GAR------------TAGK-PR----RS-----KTPFVPPASDLEKQLATLWQEILGVDSVGLNDNFFDLGGHS
LLATRVAGRLRTQFNFDIPLAK-FEAATVAALAKLVADH-----------
>tr|F8CAR7|F8CAR7_MYXFH Polyketide synthase type I OS=Myxococcus fulvus (strain ATCC BAA-855 / HW-1) GN=LILAB_26135 PE=4 SV=1
--------------------PRGWVVFTDGGPLASRLVRLEEAGQHVVTVSAGGAFSREGERRFTVSPGAPGDYAALLSGLEDSPHRPEVFVHLWSLTPR
EARADLTRFQAAQALGYSSVAHLGQALAGL--PLRLEVISNHLFDPDGQAEALPEKAPLLGPCQVLTQQQVHITARGIDVILP--G-APALAEQLVAELV
TTARDFRVALRGSRRWVQELSSVRLTESSS--PRPLRERGVYLITGGLGRVGLLLAGHLARTKQARLALVGRTPLPPRRLWASVLIQKVRE-LEAHGAEV
LVLSADVSKPRWMKEVLAEVDQR-FGALHGVLHCADLPLPPPL-SATGPEAEARFRAKVRGTYVLEEVLRGRADFVMLFSASTAVLS-PFGDTPSTAANL
FVEAFAAHQ--GSATPWMSVAWDPWPRAA----------GADLEPYAMTEAEAAEAFQRVVTGGDGPVVATGDVSRR-----L-----------------
--------TAWLQR----AVAQP-----K-----------VSRK--A------R-----TGEEAPPANELERVIAGLWQEVLGVEQVARQDHFFELGGHS
LLATQVVGRLRSRLQLDLSLALLFTSPTVAGLAKAIADL-----------
>tr|A0A0H4WVT9|A0A0H4WVT9_9DELT Malonyl CoA-acyl carrier protein transacylase OS=Myxococcus sp. (contaminant ex DSM 436) GN=A176_002367 PE=4 SV=1
--------------------PRGWVVFTDGGPLASRLLLLAEAGQDVVTVQAGTSFAREDDHRFTVAPGQPADYVSLLEALKGRAHRPEVFVHFWSLTKQ
GDVASSERFRDTQSRGYYSLLFLAQALGKA--PVRVEVISNHVHDPDGAAEALPEKATMLGVCKVLPQEHQHVATRCIDVVLP--E-ADTLARGLLAELS
TRTRDMLVAFRGTRRWVQEFTPVKMGG-DA--PHPLRERGVYLITGGLGGVGLLLAEHLAETQRARLVLLGRSAFPARESWISKLIHRVRA-MEAHGAEV
LVLAADVSDAARMRTVVEQVESR-FGVLHGVLHCAGVTHDSSLTELGTQASETQFQPKVYGTYALDEALRGRDDFVLLFSSNAAVLG-GLGYLTYASANV
FMDAFASNARGVGGTRWVSASWDGWPEET----------KHSMDQYAMTREEGAEAVRRLATQGDGPVVATGDLTHR-----L-----------------
--------AVWIHR----DAPAT-----R-----P--SGSASRQ--A------R-----KGTYVPPANETEQAIAAMWQEVLGVEQVGRHESFFDLGGHS
LLATRIVGRLRSAFNVDLPLAKLFEVSTVSGLAQAVTVA-----------
>tr|B8I980|B8I980_CLOCE Beta-ketoacyl synthase OS=Clostridium cellulolyticum (strain ATCC 35319 / DSM 5812 / JCM 6584 / H10) GN=Ccel_0978 PE=4 SV=1
--------------------GECWLLMDNGQQMSKLLADFASNNIHVISVTAGEDFIRHGNNEFTIKPSRKEDYNTLFEAIYEEGYSIKRVVHLWGLYEK
EKEL--DHYSKFMDLCFYSIINVTKAIGRYASPLTIDIVTSNMERVKQDEEVCAEKAVVLGPCRVIPQEFPNITCNSIDIDLNGKATA----AEIVRELY
ANCSGDTIAYREGKRWRQDFEEIEIGENNIQ-QPRLKEKGVYLITGGLGGIGLVLAQYLAEETQAKLILTGRSVFPEKSEWINKKICLLKT-LEAAGAEV
VVARADSADKVQMQELIASIRQR-FGGINGVIHTAGVP-GGIIQMRSADKMEAVLAPKVKGTLVLEEVLKGENDFLVLCSSTLAILG-GIGQVDYCAANS
FLDAFAHNYMLKYGTYAVSINWDAWEEVGMAVNSAAQYAPLKKEEDFI--DITHPLFKRYKKETDRVVESKFDIESC-----------------------
----------WLLK----EHR-V-----M-GSTIPGTYLEMASATFNI----LT-----ENSYVELQDVDEKENKQVYTV------FEREDDSYILRVKS
FDGQKTVEHVSEEFGT-LDLKEIIGKC---NTSVYIPDT-----------
>tr|A0A0E4HBZ6|A0A0E4HBZ6_9BACL Non-ribosomal peptide synthase/amino acid adenylation enzyme OS=Paenibacillus riograndensis SBR5 GN=PRIO_1737 PE=4 SV=1
-----------------------CLLFANDDLISRELL-LRSSGQRVIPVYRGHEFS--DDGEYTIHPESLADYQQLFAVLQEKQVEADNLIHLWSLENR
VSA-DAAAFHESQKNGFYSVTYIVQCLHQFNKAVRIAVVTDEVFPVTGQETLHPENAPLIGLGIVIPQEMQHIRHLTVDIQAASAAEARELARMLLEELG
---RDRQVSYRGLQRWVPIYQPIKLEPQIV---DLFRTNGVYVLTGGAGMIGWIIAEHLAINYRASIAIIQRS-FPVRPEWTSRTIQEMIQ-AEKLGANI
AIYPADVSDYGQMADAIGAIECE-LGAINGVIHCAANMGE-PVTRLDEALCRTIFQPKVDGLLVLDKLLEDKEDFCLLMSSTAAVLG--YGFAAYSAASV
FMDTYMKIRNKHRQVKWKTVDWEAWRREAKAE------AGYSIGDLAMSPEEGIEALTRVLS-AYHHMHSPGILDKR-----L-----------------
--------AEWVQL----QGISEGK-PVQ---P-----RDGQKKRQRP----AA-----MVEYEKPSNHLEKQIAGIWEEFLGIRDISIHDNFFELGATS
LTLIRIKSIVEETLSLQIPIVD-FANPTIAALAKRIGQI-----------
>tr|A0A0Q5SLL1|A0A0Q5SLL1_9BACL Uncharacterized protein OS=Brevibacillus sp. Leaf182 GN=ASG16_14625 PE=4 SV=1
-----------------------FLVFANRDSLSSEVI-LSSTGQIPIVIYEGVEFA---ERAYTVNPTSSSDYEKLFVSLTENNIQIDHVLHLWSAGHK
SSA-DVLAFHKTQQTGFYSIMYIVRCIQRYHRVIRMAVVTNEAMAVTGQETLFPEHSPLIGLGHVIPQELQNIRHLTVDIQSAALEDAKRMAQMVVEEFA
---SDRLIAYRHFQRWVPSYQPIKLTEA-----DPFRKNGVYIITGGAGMIGWIIGSYLAKQYQATIAIIQRS-FPLKQEWRSMRIREMME-AEQLGATI
EVYRGQVDDYPQMSHIIAEIEAT-HGSIHGVFHCAANMGQ-PIDQLNADLCQTIFQPKIDGLLVLDQVLEQKSDFCLLMSSTAAVLG--YGFAAYSAANV
FMDSYTNKRNKQRSVKWKTIDWEAWRNHEKVE------IGYSIGDLAMTPEEGIEALRRVLS-VYHHLHSPGDLEMR-----L-----------------
--------DQWIRF----QGSPEGN-AVT---V-----KSARKKRKNT----SS-----MVDYEKPSNQLEQRIAEIWEEFLGIQEISTHDNFFDLGATS
LTLIRMKSILDEEFNRQIPIVD-FANPTISSLAKRIQQD-----------
>tr|L8LL59|L8LL59_9CHRO Polyketide synthase family protein OS=Gloeocapsa sp. PCC 73106 GN=GLO73106DRAFT_00014290 PE=4 SV=1
--------------------QRSWLIFDNL--------ELERENQTVIVAKSGENFARISAKDYTINPENSQDYKELLETLQELGKIPEAIA--------
--------WQLNDRFSFNSLLYLVQAIHSTTQPIQLIVITRGFYEVIGTENPNPDQATILGLCKVIPQEFPQITCRQIDIETNTDL----------MEL-
-NESEAVVAYRGGYRWLQTYQPLSLPQPQN---LPLREGGNYLIAGELEGLGLIYAQYLAQAAAAKLIFIAPLDFPEKAQWISNCIHKLQA-IEASGTEI
DLFRADLADEAQISEII----AK-LGEIHGVIHGDKMGD-RLIADLTPEKCHYLWRSKIQGLQVLEKTLRSKNDFYLLQSSLSSVVG-GVGLAAYAAGNT
FMDALAHQKHKKGSTPWFSVNWDAVRAETSPLVT-----GFDLVDFALTPDEVWEVTQRIIAWSNSQIISATDLPSR-----I-----------------
--------SKQ-----------------------------PTQEHTRP----VL-----QTPYVAPSNEVEQKVAEALQELLGIEKVGIHDDFFELGGHS
LLAIQAMSRLREIFQIELPMREPFESPTVAGIASTIIRL-----------
>tr|C7Q555|C7Q555_CATAD Beta-ketoacyl synthase OS=Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897) GN=Caci_6994 PE=
--------------------AGPWLVLSDDER-TETLIRLGEAGAEVVAVRPGAAFD--DVGDFVI--PRLDDFAELFES---MLVAPRTIVHGFSLGGV
VFDAPVISFSAAQERGYHSALALARYLVDDATPLDLVLLTSGATTVAGADLRHPEHATLAAIAATLSQENPRLRAREIDIDAVAAGTAERFRAEAVLAAA
---YEGPVAERAGQTWLRRYLRH---PLP----AAFKNGDRVLITGGLGDVGLTLSRHLAT-GYGCLILCTRSTLPPRSAWRTRHVQNILA-LEASGAEV
IAMTADVADPVAMQAVVDAAVAR-FGGIDVAVHGAGVQDR-FAHLTEREQSEAHLDAKIRGFLVLDQVLAGHCERRITLSSLSAVLG--LTLGAYAASNA
GLDAYARAARAAGSGRWVTVDWDTWNIDERLDGH-G--PT--VTDFTMAPAEGVDVFERALAASVGHVIS-------TGPARL-----------------
--------AQWVT---------GG----GAD---GGDDDDVRERYARP----DL-----PTPFEEPRPGTEAALAEIWSAALGVEPVGALDDFFALGGHS
LVAIKVTTRIRKTLNASVPATA-LEAPTVRGLAALIDG------------
>tr|A0A0E4CVH1|A0A0E4CVH1_9BACL Uncharacterized protein OS=Paenibacillus riograndensis SBR5 GN=PRIO_1751 PE=4 SV=1
-----------------------FLLFIDDSGLGEGIQ-LSAKGNRVCTVKMGAGFG--HRDQYEIDPDNAEHYLQVFRQVFQTGHPVWKIVHMWSSREY
MPD----------SGGFYSLLHMGKSFGMIHQQIQLTVVTSAFQSVMGNEVLTPSNAAATGAVHVIQQELQNVRTALIELAGEDTGYDQAALELLLEEFI
---PERFLAVRGRRKWVRAFEPMQMDHPA----LKQKRDGVHVILGGLGGIGLTAAQALAEQGAGTLILTGRTSFPPEAEWINQKIRKIIE-LQEQGAQV
YLYQVQVSDEKRMNGLFTSIEHT-HGKIQGVIYSAGTVVDFSISGITREMCEAEFEAKIRGLIILERMIRGKDEYCMVNSSISTILG--IGLAAYTAANQ
FMDSFVQMMNQQNRTRWMAVDWDAWNFSASDKAG-----GTERLDQFIHPAEGGAVIKALFQVMTEHIVSTTELEPR-----L-----------------
--------ALWVNH----SRNNEPG-SQR---E------------------------------SRKELSIEQLLQERIREATGLSGMGADENFFDAGITS
IDIVGMNDSIQQHINRPILISS-YEYPTIKKLAGYLQGE-----------
>tr|A0A0C4WWG1|A0A0C4WWG1_9GAMM Polyketide synthase type I OS=Azotobacter chroococcum NCIMB 8003 GN=Achr_38910 PE=4 SV=1
--------------------TGSVLLLSDAHGLGERLAHL-QAQRPVIRVERGAEFARLGERRYAVRPGERDDFERLLRAVEAESGPLADICHLWSLDPA
GLPA----PDEALERGFHSLLALAQALEATRRSVVLSVVANQLEDVTGVEPLCAEKATLHGPCKVIPQEYPHVACRLIDVVLPPAG-EERLARQLAAELA
TPEGTPVLAYRGPHRWLKTFESV----R-----PRLRRQGVYLITGGLGGIGLALARHLAGNWQARLVLLGRSALPPRDEWLAARLQQLLA-LEALGAEV
LVLQADVADPAQLRQAVDAARQR-FGALHGVVHAAGAAGG-VLAGKSRADAEKVFAPKLQGTRHLLEALA--TDFVLLCSSLTAITG--FGQADYCAANC
FLDALAAESR-QADRFVLSVNWDTWRETGMAAGQRLP------EKVGIAPEQGGRLLEALLGGPTAQTVSTLDLERQ-----F-----------------
--------AQMRTS----ELAERL----L-SP-----AR--RQQHARP----AL-----QTAYVAPDGELEEDLAALWSEFLGISPIGVDDNLFELGGDS
LLAIQLLARVRSAYGVELHPAA-FKTPTVAALAMLVETR-----------
>tr|A0A0K1JVC9|A0A0K1JVC9_9BURK Polyketide synthase OS=Massilia sp. NR 4-1 GN=ACZ75_05725 PE=4 SV=1
--------------------SGPILLLADETSFADKLASL-LAGREVVRVERGSGFERIAANCYAVRPGDAGDLAQLLQALES--AAVIDVCHMWALNSG
SQP-------DALERGFHSLLALAQALDS-VGAAAITVLSDGLADVTGTEQLHPQQAALYGPCKVIPQEYPNISCRLLDIVLPAAG-EQTLV----NQVI
GVQGGTLVAYRGPHRWLKEYEAL----S-----QRLRRHGVYLITGGAGGVGMALARYLARTWQAKLVLASRNALPSD-------APGLLE-LEALGAEV
LAVQVDVGDAGQMTAAVAAARAR-FGALNGVIHAAGIAGG-LIATKQRASVEKVFAPKLQGTMVLLDAVK--ADFVLLCSSLTAVTG--FAQADYCAANA
VLDALSQRAS-GDGPWLVSVNWDVWRDLGMATGHQLP------EDEGIAAADAGPLLERILSGPLPQVISTIGLERQ-----M-----------------
--------ARGASM----ELADRL----L-PP-----PR--RQQHARP----AL-----SEAYAEPSGPLEEGLAALWIEFLGIAPVGTNDNLFELGGDS
LLAIQLLAKVRGAYGVELHPAG-FKNPTVAALAVMVETR-----------
>tr|N6YXT2|N6YXT2_9RHOO Beta-ketoacyl synthase OS=Thauera phenylacetica B4P GN=C667_00485 PE=4 SV=1
--------------------RGSMLVIGDPNGLTDRLCEL-RAGRTVVRVEQGHEFAQMGAHRYAVRPGERADLERLLRHVEAEVGLPSDVCHLWNVELG
DVPS----PEEVLERSFFSLLALAQVLGA-GRKVSLTVVANQLEDVTGTEPLCPEKATLHGPCKVMPQEYPHLACRVVDVLPSADA-LDRVV----QQIV
AMDGESVVAYRGPHRWVRTFEPAHPALR-----QRLRKNGVYLITGGLGGIGLTFARYLARQWQARLVLIGRNISSDQ-------AKAVAE-LEALGAEV
LPLQADVADAVQMRAALDEVRRR-FGVLHGVVHAAGVAGG-MIAQRERAAVEQVFAPKVLGTQVLMSQIA--ADFVVFCSSLASLAG--LGKVDYAAANA
YLDAVAADAR-SPGASVVSVNWDGWREVGMAAGTPLP------DQFGIGPEQGVLIFERVATGFHPQVVSTTDLSAR-----L-----------------
--------DVNGD-----AILSIM----A-AP-----PHRPDRSHPRP----RI-----SAEYVAPSGDLECGLARIWTDVLGIAPLGADDNLFELGGDS
LLAIQLLAKVRSTYGVDLHPAV-FRDPTIAALAVLIEMR-----------
>tr|J2KPR3|J2KPR3_9BURK Polyketide synthase family protein OS=Variovorax sp. CF313 GN=PMI12_02852 PE=4 SV=1
--------------------GTCTLVFGEAGGLAGQLVHLRESAHPVVWVEQGPGFVEIGPRHYAVRPGERADHEQLLRKVQGGIGPVSNIHHLWGVDGE
FAAP---SSSELLERGFFSLLALAQALDSTERKLLLQVVTNRMEDVSGLEPLCPEKATLFSLAKVIGQEYPHIGCRVVDVVLPVSG-EAWLVAQLAADAP
A-RDEPLVAYRGPHRWVKGYEPLALPA------QRLRTHGVYLITGGLGGVGLSVARHLARSWQARLVLLGRSPLPERAAWLRQKLLQLLE-LEALGGEV
LVLSADVADAAQMQAAAAQARQR-FGAIHGVIHAAGHASG-MISQRTRAMVEAVFAPKLRGTQILLEAVR--PDFVLFCSSISSMAG--LGMSDYAAANA
YLDALAAQRR-SAGHAVFSVNWDAWRDLGMAAGMVLP------EGVGMDGPEGALALERIVNGPHAQVISTTDLAQR-----L-----------------
--------GELDS-----GMLALI----E-NA-----ARATRRNHPRP----AL-----DTPYVAPGGDLETGLAAVWQDMLGITAVGVNDNLFELGGDS
LLAIQILARVRKAYDIELHPAA-FKAPTIADLALLVETR-----------
>tr|A0A0P9B6C7|A0A0P9B6C7_VARPD Polyketide synthase OS=Variovorax paradoxus GN=APR48_34060 PE=4 SV=1
--------------------DGCTLVIGNADEFQRAFVHLRQAGHAVVRVDHAQAFAEHAPHHYALRAGERADHEAVLRKVRSAFGPVARIHHLGGIDAD
APVA-DAAAETALERGFFSLFALAQALEAVERRLSLQAVLTQSEDVAGDELLCPEKATVFSLCKVIGQEYPHIDARVADVVLPAAG-QARLFAQLAAGAH
A-TDETRIALRGPHRWVRGYEPL--PA------QRFRQGGVYLVTGGLGGVGLAVARHLAASWQARLVLLGRSPVPARTEWLRAKLRQLLE-LEALGSEV
LALSADVADAAQMRAVAAQARER-FGAVHGVIHAAGHADG-MIGQRTRARVDAVFAPKLRGTRCLLEALR--PDFVLLCSSISSMAG--LGMSDYAAANA
CLDALAALQR-SAPYPVVSVNWDAWRDLGMAAGRVLP------EGIGMDGPEGARALERIVNGPFAQVISTTDLAQR-----L-----------------
--------GQLDN-----GMLALV----E-TA-----VRKKRRSHPRP----AL-----STAYAAPDGDLEQGLAGLWQEMLGIAGVGVDDNLFELGGDS
LLAIQILARARKAYEVELHPAA-FKAPTIRELAVLVETR-----------
>tr|E6V980|E6V980_VARPE Beta-ketoacyl synthase OS=Variovorax paradoxus (strain EPS) GN=Varpa_4326 PE=4 SV=1
--------------------DGCTLVFAETSGLTDALIQLQAEAHPVFRVTPGSGYAETGAHQFTVRPGERADHEELLRKVQAESGPVAKVYHLWSVDGQ
PSSS-LPQSEDVLERGYFSLLALIQAIDSTARELSIEVIANQIEDASGLEPLCPEKATLFSLCKVIAQEYPHIACRVTDIVLPVPG-EAWLARQLAAPAQ
A-HDETLVAYRGPHRWVKTYAPL--PS------QRLRSKGVYLITGGLGGVGLAVARHLAESWQARLVLLGRTPLPERSEWLRTRLAQLIE-LENLGGEV
LVVAADVADAASMQAAVAEARAR-FGMVQGVVHAAGHANG-MIATRTRAAIDEVFAPKLQGTRFLLDALR--PDFVLLCSSISSMAG--LGMSDYAAANA
YLDGLAALQR-SATYPVISVNWDAWRDLGMAAGRVLP------DGIGMDGPEGARAVERIVNGPFAQVISTTDLNQR-----L-----------------
--------GELDN-----GMLDLL----E-TA-----AKKKRREHPRP----AL-----ATPFVAPEGELENVLAGIWQDMLGIASVGIDDNLFELGGDS
LLAIQILARARKAYEVELHPAA-FKAPTLRDLAILVETR-----------
>tr|A0A0M8SG13|A0A0M8SG13_9ACTN Uncharacterized protein OS=Streptomyces sp. WM6372 GN=ADK52_05045 PE=4 SV=1
--------------------AERWLVFADETGVGRRLARLEALGATVRVVSRGADWHREGEREYVLDPARAEHFGRLAEALRAEGPLPGRVVHCWSVGDD
ADRA-PEDVRALLHRSFDSLVHWAQAVEAETQQQRWDVLSSEVHSVLGDEPLCPPKAAVQGLCRVLPQEYPTLSCVQFDLRLEGPQ--PGLVEQLLADLS
A-PGERTIALRGRHRWAPAYAVGEPPARD----SPVRDGGVYLLTGGLGKIGLLMARALADRAKVRLVLLGRTGLPPREEWVRSAVRAVQE-IEALGSEV
LVTATDVSDRAAMLALKARILEE-FGPIDGVLHCAGTTGA-EISVLGEEEASWHFGPKLYGTQVLHEVLADQRDFALICSSIASLLG--LGFGAYAAANA
VLDAFAQKHH-SADLPWTSVNWEAWYFSEDRADS-----ELAVRDLALTPAEGRRVFDALLDAAQAQITSTGDLALR-----Q-----------------
--------ELWSDP----SA-----------------AAAPVTRHERP----NL-----RNPFVAPSGETEQRVAEIWQELLGVESVGAQDNFFELGGSS
LLGLQVVHRLRQELSVAVPLTI-YEGPTVRALVDNLRAA-----------
>tr|A0A0N0YHG7|A0A0N0YHG7_9ACTN Uncharacterized protein OS=Streptomyces sp. NRRL S-4 GN=ADK82_17930 PE=4 SV=1
--------------------AQRWLVFADETGVGRRLARLEGLGATVRTVVQGAEWHRKSEREYVLDPAQPDHFHRLAEALRAEGALPGRVVHCWSVGDD
ADRA-PEDVRALLHRSFDSLVHWVQATEAETQQQRWDVLSTEVYAVLGDEPLCPPKATVQGLCKVLPQEYPSLSCVQFDLRVESRQ--PGLVDQLMADLA
A-PGERTLALRGRHRWAPAYVTGAPPSRG----SPVRTDGVYLITGGLGKIGLLMARALADRAKVRLVLLGRKGLPPRSSWVRSAIRAVQE-IEALGSEV
LVTATDVSDRAAMLALKERVLRE-FGPVNGLLHCAGTTGA-EVAVLGAEEASWHFAPKLYGTQVLHEVLADQHDFAVISSSIASLLG--LGFGAYAAANA
ALDAFAQRHH-SAALPWTSVNWEAWYFSEDRADS-----DLAVRELALTPAEGRLVVDGILDAAQAQIISTGDLTLR-----Q-----------------
--------ELWSDP----VA-----------------VPAPARRHERP----NL-----RNPFVAPDSETEHQVADIWQELLGVESVGVQDNFFELGGSS
LLGLQVVHRLRQELAVAVPLTI-YEGPTVRVLIDNLRTA-----------
>tr|D9UX73|D9UX73_9ACTN Modular polyketide synthase OS=Streptomyces sp. AA4 GN=SSMG_04284 PE=4 SV=1
--------------------PRDVVVVNRSQ---DSLAPLRAAGIRVRYA--A----------------DAAGV---A---AYAERTPTDVCWFWRPAAG
GM----------LPEEYSDLLSTLDILQRRGQGQRFWLVTEGAQQLPGD-A----AASLWGFGRSLWSESPAYRPTLVDVVEGDYAELRRISKDILETV-
-ITTAYSLDEIEAFGVLSRGANVGKLVLDFAE-VALSPDETYLITGGLGALGVVTARKL-DEGARHLSLVSRREPDAR-----AIADLAQR-L---GERV
EFYRGDIADAADVGRIAEAIGAA-GRPLGGIVHAAGVLADGPISAMTWEQIDRVFRTKVYGTWLLHEMA-P-EKFFVGYSSMSAALG--AGQANYAAGNT
FVDAVMTRRA-AAGQAGLSVGWGPWAEVGMAASLT----EQGLR--FLKPRAGARALGKLLG-QVSEVMVGEEWDR------F-----------------
--------VPSRPA----A---NALFTAT---------------VADRSVLDALRA--LP-K--LERRAINEAVRARIADLLRFGDISPQAKFMELGVDS
LMAVEMKNALESAFRV--SLSVVFDYPSVAVLAAFVDEQ-----------
>tr|A0A0A6P534|A0A0A6P534_9GAMM Uncharacterized protein (Fragment) OS=Candidatus Thiomargarita nelsonii GN=OT06_47975 PE=4 SV=1
--------------------SSSWIIFADQG------ILLQAQGERCVLVFVGQNYEK----HYTINLSNPDDFQRLLEDSLAHYPPCRGIVHLWSQDNG
FEND----LRHAQILG---VLHLVQSLIQASQFPHLWLVTQGGQAIGQ----NIEQSSLWGLGRTIMLEHP--EFQCVCLEGKTDTNPAL-ITLMLKEL-
-LYKCFPIAKVVAFRYLAQAKQIGKVVI-SL--SIVHGNSSYLITGGTGSLGLQMAQWL-EQGAQHLILMSRQTTTTDIV-----KHTIAQ-IEQTGAFV
SIATADVSDENELNRVLEQIN--QTAPLRGVIHAAGVLEDGMLIGQNWERFEKVLAAKVYGAWNLHQLTAP--DFFVMFSSAASLLG--RGQSNYAAANA
FLDSLAHQRH-QQGLVATTINWGPWAQGGMALSTT----TIGFK--PINTLEGLELMERIIS--ITQIVM-PDWHK------Y-----------------
--------TTADN---------VLFTTDK-PA-------KP----LAELS-LKLEK-AG--GY-EEKHILSNFVHETAQQVLGTQ-LDANKSLMELGLDS
LQAVEMRNRLGKGLET--TLSLLFNYPSINKLVGYLEKE-----------
>tr|A0A0M8SUD2|A0A0M8SUD2_9ACTN Beta-ketoacyl synthase OS=Streptomyces sp. WM6378 GN=ADK54_22725 PE=4 SV=1
--------------------DRHVLVLGGER------AAAETSGVRLTRL--A----------------GT---DALP---DLADPSVTDVCWFWRPDGR
P-------SAAVLRAEYRDLLAVVTALTGANTAPRLWLVTERAQWLPQDRPGTG-AATLWGFGHVLLNEYPRYRATLVDLP---EG---QSAGRALRDV-
-VTLAFALDEADALVTDRQEGAAQPVV-TLAP-PVVRPDRTYLISGGLGGLGLVTATKL-DLGARHLVLVSRSGRPTP-----EAEPVLEA-L---AKEI
VLARADLGDAADVDRLFAEIRGG-RVPLGGIVHAAGRAGSSLIGNLTWGAIDEQLQAQAYGGWLLHEAS-P-DDFFVVHSSIAAVVG--STQAHYAAAFA
FLDGLVAWRT-RQGLPAQATNWGMWSRVGMSARLD----ENGMR--FFSPARALRTMERLLP-AAPQYVAGEDWDR------F-----------------
--------VSLNPL----D---NALYASGDQ------------PAGRPAVLSALVA--KP-K--PERVVVGQVVLASVAAALHAEEIDPTTEFVSLGLDS
LMALELKTSLESVFKV--ALSLAFDFPSPQLLTEFLDAQ-----------
>tr|A0A0N1CHC0|A0A0N1CHC0_9MYCO Polyketide synthase OS=Mycobacterium immunogenum GN=AN912_16755 PE=4 SV=1
--------------------PANAIVIAQV---PLAVAGARRAGVAVLNVVEKANLAE----TFAEAL-HRDEFLRVLVTV--------------GSGKS
AV--------------VAGLVTVAQSLRMVSPDVQVVLVSKNAFLAPGDRDLDLDQVALVGARRVLANEHPAKWS-LVDLPAAASARPEIF-RELRREC-
-LYTRFPIEEIVAFEAVFRAEHMGRIVLDLR--VPVRPGHSYLITGGFGGFGLATARSLARAGATHLILASRSGATTDVA-----RAQIEA-LRAADVDV
WEERIDISDYDQVADLVAKVEAS-GHPLRGVFHAAAVAHDEVIADISAESLHKVFGPKVEGARNLDKATRD--DHFVLYSSISGLIG--VPQLTYAAANS
MLDGLAASRH-AAGLPALAVSWGAMSGGGMAESDAI---VKGLR--RLNMDMGAAFIQECSR--LPQVIA-GDWGVL-----------------------
--------RTPLPS----TAK-STRFAAA------------VSNEQAAFR-AAVLG--LPEE---ERGMVTKELAKELANVLKVDSIDPKGPIADLGIDS
LMAVEFAARAGKQLNI--QIFQFTPDLTLEARVALLIAQ-----------
>tr|A0A0E3XMW9|A0A0E3XMW9_MYCCH Polyketide synthase OS=Mycobacterium chelonae GN=GR01_10600 PE=4 SV=1
--------------------AANVIVIGDV---AAAFAGARRAGAVILKA-PGADLAD----AFAAAL-HADTYLRVLATV--------------GAGKT
LV--------------LHQLVTIAQALRVVSPDVQVVVVSTRAFLAPGDSGLDLDQTALVGARRVLANEHPAKWS-LVDLPDSATPRPETF-RELRREC-
-LFTRFPIDDVVAFEAVFRAAHMGRIVLDLR--APVRPGHSYLISGGFGGFGLATARSLARAGATHLILAGRSGATTEVA-----RAQIEA-LRAADVDV
WEERIDISDYDQVSDLIAKVEAS-GHPLRGVFHAAAVAHDEVLADISAESLYKVFAPKVDGALNLDKATRE--DHFVLYSSISGLIG--VPQVTYAAANS
VLDGLAQARH-AAGLAALSVSWGAMSGGGMAEVEAI---VKGLR--RLNMDLGATLMHECSR--LPHVIA-GDWGVL-----------------------
--------RTPLPS----TAK-STRFAAA------------VSNEQAAFR-AAVLA--LPEE---ERGMVTKELAKELANVLKVDSIDPTGPIADLGIDS
LMAVEFAARAGKQLNI--QIFQFTPDLTLEARVALLIAQ-----------
>tr|D0KZC3|D0KZC3_HALNC KR domain protein OS=Halothiobacillus neapolitanus (strain ATCC 23641 / c2) GN=Hneap_0958 PE=4 SV=1
--------------------VRLIGINCPD----KPHLSHFE---LVADI--D----------------KA---L-DA---ITSQGKPTKFVCFWNGKEL
PAD-----DADAIMAAYEPLLAFIKALAKLKETVELVFVTKGVQTTGREDARAG-QATISGFCSVLNSEFSRIRAKVVDLPCMGEDELLDLNKSILEDI-
-PVTSYSVTDIAAFGVLSRGENVGKIVLTFGR-RVVSGEGTYVITGGYGALGQRVARCL-QAGARNVTLLGRNLPNQD-----ALAQLKMR-L---DGNL
DLCTGDVADSDVVDRIFVEAAEK-GRPVCGIVHLAGLISDAPITEQTWISFRTVFLPKVVGTWNLWKAA-G-GELFAGFSSIASVVG--VSQSNYASANA
FIDGLMNRTR-GGGRIGLALNWGPWGGAGMAAELT----DQGFS--LIPMQLGMEAFGRLAR-QQGQVVIGNDWSA------Y-----------------
--------KESLPG----D---DSLYAKS--------------DAPSDVFYNSLLA--LS-E--DQRKIVLEKLILILRQVLQYERVSRRATFSDLGIDS
LVAVELRNTLEKSFGI--ALSLVFDYPSVPVLSGYLLEY-----------
>tr|A0A0P0RGB6|A0A0P0RGB6_9BURK Malonyl CoA-acyl carrier protein transacylase OS=Burkholderia caribensis MBA4 GN=K788_0006363 PE=4 SV=1
--------------------PQTVVVGCPD----KHYLPLAT---IVGDP--G----------------HARDAL-DE---LLNARSRSQIVWFWHAEEI
SAE-----DADSMMNAYEPLLEFVKSLEHRRHLVELCIVTFDGQSVEPFDLKHV-QASASGFCAVLNSESSRVRARTIDLSRFDDIELLLMNHAILDEI-
-PVTCFPVAESAAFGLLARGENIGKIVLTFGE-REIDMHGTYLITGGYGALGQRTAQSL-KAGAHHIALLGRHLPDSA-----TLDTIRAR-L---AGSV
ELLTGDVADPTLVERIFTDAENK-GRPVRGIVHLAGVINDAPVVEQTWDKFRTTFLPKVAGTWNLWRTA-G-ADLFACYSSVASVIG--VSQINYAAANA
FMDGLMNRNR-NGRRVGLSLNWGPWAGAGMAAELT----DQGIY--LIPLQRGIEAFGRLVR-CQGQLLIGEDWHA------Y-----------------
--------KASLPA----H---DPLYQSD--------------SVSSETFVERLFT--MP-V--EQRKAVVDEVLRVLRQVLQFDRMPRRASFADLGIDS
LVAVELRNSLEKSFGV--AVSLVFDYPTVTVLSTYLLEQ-----------
>tr|A0A0F0HDT1|A0A0F0HDT1_9ACTN Modular polyketide synthase OS=Streptomyces sp. NRRL F-4428 GN=UK14_07525 PE=4 SV=1
--------------------ARRILVVGRDA---AGAVELTAADAALAFA--P----------------DVASAA-RA---ASLAGRPTDVAWFWRDRPG
PV------TEERLRAEYRDLLALLASLEQQGREQRLWLVTEGAQRLPGD-V----ASSLWGFGLSLWSEYPTYKVTLVDLPDGGDAELRSVNKQILETV-
-ITTSYSLEEIEAFGVLSRGANIGKLVLDLTA-VEIAADRTYLITGGLGAIGTVTAERL-ALGARHIALVSRRAVSAE-----RTAAIAAG-L---GESV
TAYQGDIARAEDVRRIAEDLKAT-GRPLAGVFHGAGVLADMPVSAMDWESIEKVFEAKVFGTWQLDQVL-P-EPFLVGYSSVASVLG--VAQGNYAAGNA
FVDAVMRWRS-AAGLPGLSIGWGPWAEVGMAANLS----ADGMR--FLKPTDGARCLFKALG-GESHVTVGEDWDR------Y-----------------
--------ASGRPA----V---SALYASA---------------AAVRKVLEALRA--LP-R--AERRTVNELIRERIAVLLHFDDVPADAKFTELGLDS
LVAVELKNALEAGFQV--PLSIVFDYPSILLLAEYLDQE-----------
>tr|K0K8B3|K0K8B3_SACES Polyketide synthase type I OS=Saccharothrix espanaensis (strain ATCC 51144 / DSM 44229 / JCM 9112 / NBRC 15066 / NRRL 15764) GN
--------------------SAWLLFLDADGR-AQALAVLTAAGQVVTTVLPGAEYR--RRGVYELDPARPEHYRQLFAELRALVRTPSTVLYCWPLAPS
A---------DD-TRDYFGLVRLARAVAAEVHDLRLGVVTSGAFAVTGAEHADPVARMLSGPVLVLPTEYHNLDCVQLDLPAHADG---TA-TALTRAVL
---TDPVLALRGDRWWRREPARATA-PPA----LPVRRGGVYLIVGGLTGIGAALAERLTT-GHGAVVLLSRSAHE-----P-----TVRA-LADAGATV
AAERADVSDVVALTAALDRVRAR-FGRIDGVVHAAGVAGG---ERRTDLEMAGVLAPKVAGARTLLAALRPGEDFVVLCSSLAAVVP--YGQCDYSAANA
YLDGLAE--SRSDGRLVLSAAWDTWGETGMLRDA-EVPGDLEVLARALTTAQGVRAFEALLAGRH-VLARA-GIGEPLDLGAD-----------------
--------GPWS-------------------------TGGGVTTAPRP----DL-----AEPYVAPRGELEAQLAELWQELLGVDDVGVNDNFVQLGGHS
LMAAQLAARVRAAYEIEIPVRV-FEGATVAGLATMVEEA-----------
>tr|A0A0M9YV40|A0A0M9YV40_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. WM4235 GN=ADK55_05620 PE=4 SV=1
--------------------QTWLVLCDAEGA-TQPVILITARGQIVTVVRPGPEYR--RRGVYEIDPGDPSQYAKLLADLRGLVRPPTAIVHGWGLAPA
A---------DDGTQGYFGLVRLARAMTEAVNDVRLGVLTAGAFRVLDGERPDPAAALLSGPVQVLPEEYANLRCAQVDLAPGAR----SA-LDVLRAVV
---PARLLALRGADLLTRAVEPTRP-VAP----AGSAPGAVWVVTGGFGGIGRTLAGHLAR-TAGAIALLGRHPVT-----DEPAAEFVGD-LRARGTEV
LCLRADVADAHSLAEALDRVRET-FGGIDGVVHAAGVPGG---ELRDDDEARAVFAPKTAGIRNLLAALRPGEGTLLLCSSLATLVP--YGQADYAAANA
YLAAAGEAEDARGERRVITVNWDMWASVGMASDA-EVPADLRMLAGALTPAQGTRAFAALLEGPQ-GVARA-GAEVTDDGLTA-----------------
--------EPTA-------------------------ARPSTTLLPRP----EL-----ATAYTAPGTPTEERLAEIYGEMLGIDRVGIHDDFLDLGGHS
LLAAQVVARLRAEFGVDVPARA-FEGGRVADLAVDIEDR-----------
>tr|A0A062U4M9|A0A062U4M9_9RHOB Uncharacterized protein OS=Hyphomonas sp. T16B2 GN=HY2_01130 PE=4 SV=1
--------------------SGKWVVLADNAAFGKALAGFETGGAEALLGTPSGTCAGDA----------ADSIRTLNALINEANGALSGIIIALGLEDG
ANIP----------RLRYDVLS---ALARHERPVRIVLATRGGLPVLEETVTDPEVALAFGAISVLAAETTHLMPQHVDFADDGKA-SQTNARRLLAEAG
-REKFELQLAWRKHRWLRRFEPIELPRAER--TDILKQKGVYLITGGLGGIGRTLARQLAEKVSARIVMTTRNAVPPRDAWMASVIKTVRE-IESLGGEI
HIEQADVVDREAMQGVVDRTREA-WGEISGIIHAAGVPGGN---LETEQEVTETFAPKVDGLRVLADVLGDTEDFVALMSSINAVRG-IAGNAAYSSANA
FLDSFAASR-PAAWENILLFNWEAWRDVGMASRVDR---SRLLYRVSITPDAGADIFQRVLAS-VDQLVSNYNLAFV-----L-----------------
--------MQERAE----LILRAH---GA-D-TSQ--ANAEGAAFSAA----TG-----D---VRFGREEEQQIAMIWEELLGGEMQGPHENFFERGGHS
LMATRVLSRLNAVTGVKLTLRDIFDSPTIGELADCVVSH-----------
>tr|A0A059G3M2|A0A059G3M2_9RHOB Polyketide synthase family protein OS=Hyphomonas oceanitis SCH89 GN=HOC_15577 PE=4 SV=1
--------------------SGNWLIVADNPISGERLVGFEASGASALLALVDKDPASVS------------FESQLSDFAGQLSGGLRGVIIAVGLETD
NNIP----------RKRYDLLG---ALARMVEAIRILVVTRGGIPVFDEPVSDSQAALVFGPISMLAVESENLMPQHIDFSANGDA-SDLNIRRLLAEAS
-QEKFESIVAWRERRWLRRFEPVALPPSQQ--LASLKERGVYLITGGTGGIGRTLALWLARNASTRIVLTSRKPLPPRDEWTSQIIKGILE-IQAAGGEV
SVECADVTDRDAMRGVIDRMLQK-WGQIDGIIHAAGSPGGK---MDDPDEVSLTLSSKVDGLNIMAELLRDTPDFIAVMSSINGILA-APGNAAYSSANA
YLDAFPNSR-PDSWKRVMVFNWDAWRDVGMATRIEV---AERFLEKAITPEAGAEIFARLLGS-INQVVTPYNLPQV-----A-----------------
--------GRQRQE----IWKRGL---DT-V-LNG--SLPSDASF-GT----SI-----P---IRFAREEERVIAAIWEELIGGEMEGAHENFFERGGHS
LMATRVLSRLNSVAGVKLTLRDVFDAPTIGELADCVIEK-----------
>tr|A0A0Q7LDF8|A0A0Q7LDF8_9BURK Polyketide synthase OS=Variovorax sp. Root473 GN=ASD34_10335 PE=4 SV=1
--------------------SGCTLVLGDANSFTDRLGTLREQGGRVILALRGKKFARTAEGQYAMRPAERVDHEALLREVESEAGPVTRLFHLWSLDGD
APAP----HAAAYEAGYFSLLALGQALDIGRAPLALTVVTDRVEDVAGTETLAPEKSTVLGIAKVLGQESPTIACRVVDVVLPAPE-EADLACRVVEEAA
A-QEDFVVAYRGPHRWTKTYDALPAQM------QRLRQGGVYMITGGLGGVGLALARYLSKTWQARLVLLGRTPLPERTEWLRRRLQQLIE-LEANGAEM
MPIAADVTDPAQLRNALAAVHAR-FGAVNGVVHAVVQPDG-MIAQRTQALVEAAFAPKIAGTLALLDALR--PDFVLFCSSVASLIG--LGRSDYAAANA
YLDALAHARR-SSALPVFSVNWDAWRDVGVAVGMDMP------EGVGLDERTGVSAFERIANGPLPQTVSISPFAPR-----L-----------------
--------RPLDG-----LF-ESL----D-DP-----APEARTGHPRP----VL-----QTAFVAPEGDLEEGLAELWTEALGIAPVGANDNLFELGGDS
LLAIRLLSRVRKAYGVELHPAA-FKAPTIAGLAALVELR-----------
>tr|A0A0H2M400|A0A0H2M400_VARPD Phthiocerol synthesis polyketide synthase type I PpsE OS=Variovorax paradoxus GN=ppsE PE=4 SV=1
--------------------TGCTLVLGDANSFTDRLATLRERGEEVVLALRGPRFARTAPGQYALRAAERSDHEALLREVEAEAGPVLHLHHLWSLDGD
RPAA----HAQVFEAGYFSLLALAHALDAVRGTLALTVVTDRVEDVAGTEPLAPEKATLLGLAKILGQEYPSIGCRVVDVVLPAPE-EAELAHRVADEAW
A-PDESLVAYRGPHRWRKRYAPLPDVP------QRLREGGVYLITGGMGGVGLAMARYLSRTWRAKLVLLGRTPLPGRSDWLRRKLQQLID-LEADGAEV
LPVAADVNDAAQLRAALAAVHAR-FGAVHGVVHAVVHPDG-MIAQRTPALVEAAFAPKIAGTLALLDALR--PDFVLFCSSISVLIG--LGRSDYAAANA
YLDALATARR-SSPLPLFSVNWDAWRDVGVALDMDLP------EGVGLDERTGVLAFERIANGPLPQTVSVSPLAPR-----L-----------------
--------RPLDD-----LF-DSL----D-DP-----AAEVRTGHSRP----VL-----QTPYAAPEGELEEALAGFWSDALGIVPVGVHDNLFELGGDS
LLAIRLLARVRKAYGVELHPAA-FKAPTIAELATLVELR-----------
>tr|A0A0F7BLQ8|A0A0F7BLQ8_MYXFU Polyketide synthase OS=Myxococcus fulvus 124B02 GN=MFUL124B02_19450 PE=4 SV=1
--------------------PKDWVVFLDSTGVGSALAELEEQGHRVARVTPGARLEELGENHFSLDPADADEPGFLLLALKSKDFKVENIIHLWSLDSR
EGEQGNERFEQAQARGFHPLLRLTRALTEA--PVELTVVGRQALDVESSDEIAPERATLPALCKVIPQEHDFLSCRYVDLGRG--PDTRALRQEVT-STA
TEAREPVVAWRGTNRLVQTHEPVRLEADTQ--PRPFRHRGVYVITGGLGGVGLMIARYLARQHQARLVLVSRWGLE-----GGHKRRAVRE-LEAAGAEV
MLARADVADDMLLSVAITQGALR-FGEVHGVIHAAGLAG-GLLSGLDAAACEPHFRAKVHGTYALELALAGRVDFVMLVSSNASVLG-GLGLAAYGAANA
FLDAFATSK--QGLTRWVSTNWDGWPSVD----------EESLDAFAMTEDEAVEAFRRVAESSGGQVVSTGDLEAR-----V-----------------
--------ARWLKR----EGAQK-----N-----Q--DTSGGATHERP----QL-----GTEYVAPTDDLELALAKVWQEQLGLSRLGIHDNFFDLGGNS
LLWLKIVGRLKRELGREVSLTSVFEAPTVAALAKKLGAL-----------
>tr|Q1D6B6|Q1D6B6_MYXXD Polyketide synthase type I OS=Myxococcus xanthus (strain DK 1622) GN=MXAN_3620 PE=4 SV=1
--------------------PRGWVVYQDVGGLGAALARLERLGHGVIRVTPGPGFRQVTEHEFTVDGREREDHAQFLRALKARSFNVERVVYLWSLDVS
-----GADFDEAQARGFFSVLRLAQALSGA--PVELTVVGREALEVESADAVAPERATLPALCKVIPQELDTVACRYVDVSTP--S---ALVREV----T
SDAPDPVVAWRGPHRQVQAYEPLRIEADTP--VWPLKQRGVYLITGGLGGVGLRMADYLARTRQARLVLVGRSGAE-----DGRRQRAVRA-LEAAGAEV
LVARADVADEAQLRTVLAEVDSR-FGALDGVIHAAGLAG-GLLGAMEPATCAPHFRAKVHGTYALDRALAGRSDFVLLVSSNATVLG-GLGLGAYAAANA
FLDAFAAAR--TGGPRWLSTNWDGWPVDAA---------EGSIDQFAMTPDEAVEAFRRVVEAPEGQVVSTGNLDAR-----V-----------------
--------AQWVRR----EGAGA-----K-----K--D-AGGTLHSRP----AL-----GTEYVAPTDEVERALVRVWQEQLGLEQLGIHDNFFDLGGNS
LLWLKIVGRMKRELGRDVPLTSVFEAPTVATLAKKLGQG-----------
>tr|A0A0H4WRN5|A0A0H4WRN5_9DELT Malonyl CoA-acyl carrier protein transacylase OS=Myxococcus sp. (contaminant ex DSM 436) GN=A176_002371 PE=4 SV=1
--------------------LKGWLLFVDSGGVGQALARLRQQGHVVTTVEAGASFSRLDTHRYVVDPRVREDLGAVLRALKESPRPVEQVVHLWSLDAA
------SSFDEAQELGFYSVLRCFQALTEV--EVDLTVVGREALEVESADTVAPERATLPALCKVIPQEQPSLTCRYVDARGP--G-VDALLREV----T
SGSTDPVVAWRGRHRHVQQHESLRLEADSL--TTPLKQGGAYLITGGLGGVGLMLADALARRCQAKLVLVGRAGLK-----GGR-QRAVQA-LEAAGAQV
LVLSADVADEARMREVVAEAEQR-FGPLSGVIHAAGLAG-RLLSGLDAASCAAHFRAKAHGTLVLERVLAGRTDFVMLLSSNAAVLG-GLGLAAYGAANA
FLDAFAASR--D-GARWLSTNWDGWPVAE----------EGSIDQFAMSADEAVEAFRRVVEAPSGQVVSTGGLDAR-----L-----------------
--------AQWLRR----GRVVE-----T-----P--AAAGGALHARP----AL-----GTDYVPPANDAERTLAQVWQEMLGLEQLGVHDNFFDLGGNS
LLWLKIVGRLKRELGRDVPLTSVFEAPTVALLAKKLAQP-----------
>tr|L7UA36|L7UA36_MYXSD Polyketide synthase type I OS=Myxococcus stipitatus (strain DSM 14675 / JCM 12634 / Mx s8) GN=MYSTI_03597 PE=4 SV=1
--------------------ARTWVVFQDSTGPGEALVELVRAGQRVVRVTPGTHLQELGEHHFSLDPTAPEETFFLLNALKAKGLDVERVVHLWSLDGS
S----TTDFDSAQERGFHSVLRLTRALVEA--RVELTVVGRMALEVESTDEVQPALATVPALCKVIPQEHDGVACRYVDLGRG--TTVSALARELL----
SDSAEPVVALRGAQRLVQTHEPLRLEQDAM--AQPLRTRGVYLITGGLGGVGLLLAGELARSHQARLVLVGRSGLE-----GGHKQRAVRE-LEAAGAEV
LVVRADVADESRLRGVLAEAEAR-FGAVHGVIHAAGLAG-GLLAGLDAAACAPHFRAKVHGTYALERALDGRSDFVLLVSSNAAVLG-GLGLGAYGAANA
FLDAFAASQ--AGTTRWLSTNWDGWPVAE----------EGSLDAFAMSSTEAVEAFRRVVESAGGQVVSTGDLPAR-----V-----------------
--------ARWVRK----EGASA-----E---------APTGTVHERP----QL-----GTEYVAPTDDVELALAKVWQEQLGLAQLGIHDNFFDLGGNS
LLWLKIVGRLKRELGRDIPLTSVFEAPTVATLAKKLGGP-----------
>tr|Q1D6A5|Q1D6A5_MYXXD Polyketide synthase type I OS=Myxococcus xanthus (strain DK 1622) GN=MXAN_3631 PE=4 SV=1
--------------------PQNWLVFTDTGGLGDALARLAESGGRVTRVSQGSDFRRVDDGVFEVDPTRPETYAALLNALAEDSCRPERIVHLWSVDSA
GE--GLAGLEHAQRTGFFSLLFLSQALAGQ--PVQMTVVSSGVQAVTGHEVLAPEKATLLGACRVLPHEVPGLSCRSIDVEAP--RTLQALVARMVGELA
TGSSNGAVALRGPSRWEQSFEQVRISAPAAD-ASRLRPRGTYLITGGLGGIGLVLAESLARQVQARLVLVGRNALPERDTWVSQRIRQVLA-LEALGSEV
LVLPADVGDAEQMAEVLRQARQA-FGELHGVIHAAGVPA-GLR---TQKAVEDVLRPKVSGTWILHALLRDTPDFFVLCSSRTAYTA-EPGQIDHCAACA
FQDAFAHQA--TGNVPIISLAWDTWREVGQAVTTQM---PDAMLAHALTPAEGVDVFERVLAQ-PTHVVSTEDLRAA-----M-----------------
--------ARSASL----LQDL----------------MGPMETDAAP----AA-----ERAAPASMDEAERELADIWQRFLGVESVALHENFFELGGNS
LIGLKVINEVKRRFGKDLPVVSLFENPTLSAMARLLTRG-----------
>tr|Q08QQ6|Q08QQ6_STIAD Oxidoreductase, short chain dehydrogenase/reductase family OS=Stigmatella aurantiaca (strain DW4/3-1) GN=STIAU_6404 PE=4 SV=1
--------------------PQRWLLVTDGQDLDSLLARLRRDGHSVTVAIAGSQAQRTAEDTYEVVPGSRASYAELLTLLEKAGRSPERIAFLRPLASC
GP--GPEGERKALEVAFHEPLALGQALAEL--PRHLVIVSSGVQAVGGHEPLHPEKAALLGICRVLPQELPHLTCKSVDVTPP--TLLALLVEQLAQELT
GPSSNATLAWRGVHRWEQSYESLSLPPPA---TAPLRPQGTYLITGGLGGLGLVLAEHLARAVQARLVLVGRTPVPERQQWLGSKLRKLLE-FEALGARV
LALSADTADATHMEEVLHRARAE-FGELHGVIHAAGVPA-GLR---TREATEEILRPKVHGARVLDRLLNGTPDFFLLCSSLTAVAG-DFGQVDHCAANA
FLDAFAQKA--EGARHIMSLGWDTWREVGQAVTTAL---PAQMLAHALSPQEGVDVFGRALAH-QPHLVSTRPLPSV-----L-----------------
--------ARSPSL----LQEL----------------AGAGAPSPST----SP-----PPATLSSVDEVESLLGDIWRRLLGISHVHAHDNFFELGGNS
LIGLKLVAEIKQRMGLEFPIVQLFKKPTLGGMARLLSPP-----------
>tr|F8CAS9|F8CAS9_MYXFH Polyketide synthase type I OS=Myxococcus fulvus (strain ATCC BAA-855 / HW-1) GN=LILAB_26195 PE=4 SV=1
--------------------PRHWLLFTDASGVGGALARLEEGGGRVTRVSPGSDFRRVDDGGFEVDPARPETYAALLAALAAESQRPERIVHLWSVDDA
GD--GVAGVAHAQRTGFFSLLFLAQALAGQ--PVHLTVVSTGVQAVTGHEVLAPEKATLLGACRVLPHEVPGLSCRSIDVEAP--GAQRLLAARLADELS
AGSSNGAVALRGPHRWEQSLEPVRLPAPAPD-ASRLRPRGTYLITGGLGGIGLVLAESLARQVQARLVLVSRSGLPERGDWTSQRLRQVLA-LEALGSEV
LVLSADVGDAEQLEEVLRKAREA-FGELHGVIHAAGVPA-GLR---TQAAVEDVLRPKVLGTWLLHALLRDTPDFFMLCSSRTAYTA-EPGQIDHCAACA
FQDAFAHKV--TGGAPVISLGWDTWREVGQAVTTQM---PDAMLAHALSPAEGVDVFERVLAQ-PAHVVSTEDLRAA-----M-----------------
--------ARSASF----LQDL----------------MGPMETDAAP----TA-----ARAVPTNMDEAERELADIWQRFLGVERVSLHENFFELGGNS
LIGLKVINEVKRRFGKELPVVALFENPTLSAMARLLTRG-----------
>tr|W4LZ94|W4LZ94_9DELT Polyketide synthase OS=Candidatus Entotheonella sp. TSY1 GN=ETSY1_00115 PE=4 SV=1
--------------------PQHWLVFVDACGLGTQLVRLQQRGQTVITVTAGDEFGQHDAFTYTLNPSEKGDYQALFRALQTGETQPNTIAYLWGVTPA
AEV-------VEGTPDFYSVLFLAQALGERTDPIRMAVIANQSQAVTGEEPLVPEKSTLIGPCRVIPQEYPHITCRHIDIVLQKAQGTEWLVDQLLTELV
TDAPDPVIAYRGQHRWAQTFEPVELGQ-RD---SALRPQGVYLITGGLSDTGLVLAHYLAQTAQAKLVLTDTMPFPDRVEWTRHKVEQLQA-MEALGAEV
IVLQADETELTQMQEAVEHARQR-FGPLNGVIHIAASR-GGLMQLKSPEQAHQILAPRVIGTQILTTVLHDTPDFLALFGSQVSVTG-GFGLIDECAANA
FLDAYAHSHGPQCPFPVVAIDWASWHWDQHFEQLAAGVPQLLRETYGITPDEAGEAFERILSSGQPQIVSTQDLQTA-----I-----------------
--------EQQNAV----TSTNV-----S--------GQLDTVQPAAP----L------DRDFAAPINETEQRVAAVWQDTFGIEPIGRDDNFFDLGGHS
LLAIQLISRLRDALHLDLPLSSLFESPTVAELAAITTAR-----------
>tr|W4LZT5|W4LZT5_9DELT Polyketide synthase OS=Candidatus Entotheonella sp. TSY1 GN=ETSY1_01950 PE=4 SV=1
--------------------ASCWLVLADAEGLGEQLVRLQQQDQTVITVSAGETFHQHDALTYTMNPLQKADYQALFQALRTSQQQPDTIVHLWNVTQT
AAD-------VEELPAFYSLIFLAQSIGEQTEPIHLAVIANQMHTVTGEEQLVAEKSVLHGPSRVMPQEYPHLTCRSIDVGLPPAGGRPGLIDQLFTELI
TDTPDAVVAYRGQRRWVQTFEPVTLDQ-ES---SPLRPQGVYLITSGLSDTGLIFAHYLAQTVQAKLILMAPAPFPGQAAWTSRKIEQLRA-IEALGAEV
LVLSATET--IDIQAVVAQACQH-FGQLHGVIHIPATR-GGLMQLKTAEQAHQVLAPRVVDTQILETALQDIPDFLALFGSNVGVTG-GLGLVDECAANA
FLDAYAHRRESAQPYPVIAIDWSGWHWDDHFEQLAAGAPQMLRETYGITPEEAGQAFELALSSAQPQIVSTRDLQTF-----I-----------------
--------DEQNTL----TTSNV-----V--------RQQDTMQPIQS----LS-----EGDFVAPATEIEERVAAVWQDVFGLERVGRDDNFFDLGGHS
LLAIQLVSRLRDALQLDLPLSSLFETPTVAGLAALAADT-----------
>tr|A0A0D8ZQK5|A0A0D8ZQK5_9CHRO Beta-ketoacyl synthase OS=Chroococcales cyanobacterium CENA595 GN=UH38_17145 PE=4 SV=1
--------------------KYCTLIFIDKIGLGIEIARLQLEGQDVITVQEGAKFTKFDDRAYSLNPQQRDDYDLLLNELIAQNTIPTAIAHLWNVTAF
DN-TKIESVEQLQDKGFYSLLFLAQAVGRQTSQLQITVVSNNMQSVIGKDCLYPEKATLLGAVKIIPQEYAHISCRSIDIVIPTDV-YEKLVDSLINELK
TQSSDIVVAYRGVNRWVQTFEPVRLEKHK-E-TSKLKQGGVYLITGGMGGVGLTLASHLAKSIQAKLVLIGRSAFPAKSEWISQKIRKLQE-IENFGAEV
LAISADVSNLEQMQKVFTTVKEK-FQHINGIIHCAGVADAGRR---TREMTAEIMAPKVKGTLVINSLLKDIQDFFIFCSSLSSVIYSKFSEVGYCAANE
FLDTFAYYKTHIEGTFTVSINWNDWLDVGM-----SIE-AVTFLMDAVSPAEGVEVLERVL-NSVPQIVSTQDLTAL-----I-----------------
--------ERDRDF----NPQA----------MLDSLKTTASATYPRP----QL-----TNAYVAPRNETEKIIAEVWQNLLGIEEVGIYDNFFELGGDS
LSIVKLHRQLQKRLQRDLFTTDLFEYPTINALAQYLSPA-----------
>tr|M4T757|M4T757_9NOSO Polyketide synthase OS=Nostoc sp. 'Peltigera membranacea cyanobiont' PE=4 SV=1
--------------------AGCWLIFIDECSLGEKIVRLTLEGNNAIIVRIGEQFSSEDRRVYTINPRRQDDYYALIKELNRLELTPNRILHLWNLTLN
SGTETIESLERCETLGFYSLVFLAQALAEQTNPMQIGIVSNNLQEVTGSEVLDPGKAFILGPCKVIQQEYSNIACCSIDIIIPETEQQEKLVDRLLAEFT
VQLSDRVVAYRGNYRWVQTFEPVRLDRVVEA-KPQLRERGVYLITGGLGGVGLFNAEYLAKTVKAKLILIGRSAFPNRDEWVSRKILKLQE-LEALGAEV
LVFKADVTNREQMEAAITQANNR-FGQINGVIHNALED-KGQK---TLEIGRIVFTPKIIGTIILDNLFKNVEDFFVLTSSQASVI-GGIGLVEYTAKNA
FLDAFAYYSASKDGKFIKSINWDIWNTPEWMAKTKLYR-VAET---GLTLEEGMESFERILFSSMPQIVSKSDFNNL-----I-----------------
--------NQKLIN----LKDT-------LNLEEESSVSRVKKTHSRP----DL-----RNAYIAPRNEIERTLTEIWQEIFSIEQVGIYDNFFELGGDS
LLATIVISQLRKTLKIEVPYKSFFDEPTITKLALVVEEI-----------
>tr|K9XCC5|K9XCC5_9CHRO 6-deoxyerythronolide-B synthase OS=Gloeocapsa sp. PCC 7428 GN=Glo7428_1765 PE=4 SV=1
--------------------SHCSLIFIDEYGVGSELVHLQQLGQEIITVKVGEKFHQLDRNTYAINPNQADDYYKLLLQLREQGKTLKTITHLWSLTQ-
----QILSWEATQNLGFYSLVYLAQAIVQQDT-IELLVIANYLYDITGNEKLYPEKATILGACKVIPQEYPNIRCRLADILLPTST--EDIIKQLLAELT
AESEDLIIAYRNNYRWVQTFESVALESATED-KIRLRTDGVYLITGGMGGMGLTFAEYLAKTVQAKLILLGRSLPSD----N----EKIKQ-LEALGAEV
LVVAADVTNEEQMQSAIAQSLER-FGTIHGVIHAAGIA-AGLK---TPEIAEKVFAPKVQGTITLNNILKNINDFLVLCSSLSAIQ-GGFGQVDYCAANI
FLDAFAHWNTTRNNQFTIAINWNTWQQVGMAVNTDV---PDESLKNAILPAEGVEVFSRIL-ANLPQVVSTQDLQVG-----L-----------------
--------EQLHQL----VLSL-------SLAQKPINCQVSASRHSRT----LQ-----ESTYVEPRNEIEQTIANIWKELIGIEKVGVHDNFFELGGHS
LLAVQTISRLREAFQVELPLRTLFDAPTVSELAHVIVEK-----------
>tr|K9U3Y8|K9U3Y8_9CYAN Beta-ketoacyl synthase OS=Chroococcidiopsis thermalis PCC 7203 GN=Chro_3720 PE=4 SV=1
--------------------SDCSLVFIDEYGLGSELVQLQQLGQNVITVKGGKEFNQLDSNTYAINPSQADDYLNLLRQLREQGKTPKTITHLWSLHQ-
----QTLSWETTQNLGFYSLVYLAQAIGQQDP-IQILVIANHLHDITGNEELFPEKTTILGACKVIPQEYPNISCRLVDILLPTST--ENILEQLLAELT
AELEESIIAYRNNYRWVQTFEPVTLEPTTED-NIRLRQQGVYLITGGMGGIGLVLAEYLAKTVQAKLILLGRSLPSD----R----EKIKQ-LEALGTEA
LVLAADVTNEEQMHSAIAQSLER-FGTIHGVIHTAGVA-AGLK---TPEIAERVFAPKVQGTITLNNVLKNINDFLVLCSSLSSIQ-GGFGQVDYCAANT
FLDTFAHWNTTTNNSFTVAINWDAWQQVGMAVNTNV---PDESLKNAILPSEGVEAFSRIL-ANLPQVVSTQDLLAG-----I-----------------
--------EQLNQS----VLSL-------SFAKKSVNCQVSASRHSRT----LQ-----ENTYVAPRNEIEQTVANIWEELIGIEKVGIYDNFFELGGHS
LLAVQTISRLREAFQVELPLRTLFDAPTVSELANVIALK-----------
>tr|K9WUC0|K9WUC0_9NOST Polyketide synthase family protein OS=Cylindrospermum stagnale PCC 7417 GN=Cylst_1519 PE=4 SV=1
--------------------SGCYLFFVDECGVGLQIIQLQQLGYDIIAIEASEQFNQLNSNTYTINPAKADDYQNLLRQLGEQGKIPQTIIHLWSITQ-
----ETLSWETTQDLGFYSLVYLAQAIGQQNA-IKLLVIANHLYEITGSEKLSPEKATILGACKVIPQEYPHISCRLVDVLLPTSA--KDFVEQLLAELT
DESESPIIAYRGNYRWVQTFEPILLEKPAED-KIRFRQGGVYLITGGMGGIGLVLAEYLAKTVQAKLVLLGRSLPSE----DSPQMEKVRQ-LEAFGAQV
LVLAADVTNQQQMQNAIAQALES-FKEIHGVIHTAGIP-GGLK---TPEIAESVFAPKIQGTLILNNVLKDINDFLVLASSLSSIQ-GGFGQVDYCAANA
FLDAFAHWNTSINSRFTVAINWDAWQEVGMAANTIV---PDESLKNAILPEEGVDAFSRIL-ANLPQVVSTQDLQTS-----I-----------------
--------EQINKL---------------GLPQKSVKSQLSATRHTRT----LQ-----ASTYIAPRNQTEEIIANIWQELIGIEKVGIYDNFFELGGHS
LLAVQTISRLRENFQVELPLRTLFDAPTIADLATVIVEK-----------
>tr|G6FSF5|G6FSF5_9CYAN 6-deoxyerythronolide-B synthase OS=Fischerella sp. JSC-11 GN=FJSC11DRAFT_1702 PE=4 SV=1
--------------------STCYLVFVDECTIGSQIVHLQQTGQDAIAVLVGAEFSQVNHNTYTINPTQKDDYYTLLQTIHQQGKIPETIIHFWSLTH-
----IHQSLETIQNHGFWSLIYLAQALGQQDSKIQLFVVSNHLYDVTGNEELLPAKATILGPCKVIPQEYPGIKCRQIDVVLPTSR--DNLVQELLAEIT
AESNESIIAYRNHHRWVQVFEPITLEKPTSR-KTRLRQKGVYLITGGTGGIGLEIAKYLAQTVQAKLILIGRSQLPAKEHWTHHKIQKLQE-LETLGAEV
LILPADVTNYEQMQSAVAQSLEN-FGEIHGVIHAAGVA-SGLK---TLEIVNSVFAPKLQGTLVLNEVLQDINDFLVLCSSLSSIY-GGFGQVDYCAANA
FLDKFAHFNTSKNGKLTLAINWDTWQEVGMAVNTAV---PEETLKNGLLPTEAVEAFERIL-ANLPQIVSTQELQLV-----I-----------------
--------DQFNQF----LSSS-------FLNSKSENTHLSGTRHART----LQ-----ETTYVAPRNEIEQSIANIWEELIGIDKVGIYDKFFELGGHS
LLAVQTISRLRETFQVDLPLRTLFEAPTVAELAIVIAEK-----------
>tr|A0A031HMT8|A0A031HMT8_9BURK 6-deoxyerythronolide-B synthase OS=Delftia sp. RIT313 GN=BW39_04578 PE=4 SV=1
--------------------GGCMLLLAEAGTLAESLAAWSDTPAPVVRIEPGPLHERLGPARHALRTTERSDWTRALGQIAAEIGPVACICDLWSLGTL
DDA-------QAAERCLLGPLALAQALEAVAGRQQMLLVTDGLEDVTGTESLQPAKAMLHGPCLVIPQELPGMACRIVDVLPVQSG-GM---AALAQRIL
AE-APACVALRGPHRWTRRYERIAGQTAPAV-TPRLRRGGCYLITGGLGGMGLALARHLAEHWQARLVLLGRSALPERGQWLRVRLQQLLE-LERLGAQL
CLVQADVGSEAQLRTALEQAQRA-FGGIHGVIHAAGLAGG-MLADKRAHEVMQVLAPKLQGTRALLAALA--PDFMLLCSSLAAVAG--LGRIDYAAANA
CLDALAVAGR-TAGWPLISVGWDGWRGVGMAAGTSMP------EGVGIAPEQGVHLFERILAGPQPLVVSTTDLETR-----R-----------------
--------HADLA-----ELLDQA----L-PA---TTTAGPAPTQVRP----GG-----MAGFVAPEGDLETGLAALWSGFLGVAPVGAEDNLFELGGDS
LMAIQLLARVRQAYGVEIHPAA-LRTPTVRRLAELVETR-----------
>tr|K9X846|K9X846_9NOST Polyketide synthase family protein OS=Cylindrospermum stagnale PCC 7417 GN=Cylst_6459 PE=4 SV=1
--------------------KSSWLVFIDDCGLGSQIVRLERDDCDVISVKVAAEFTQQSDRTYTLNPQQADDYNTLVRQISAQREFPNTIVHLWSVTKN
SQTIILEGVDKAQDLGLHSLIFLAQALGKHIHEIQLTAISNNVQPVTTEEELCPEKATILGAIKIIPQEYSSISCRSIDIVLPKSGNECKLIDQLLNELQ
AKSSDLFIAYRGLHRWVQTFEPVRLNKPSET-KLRLREQGVYLITGGLGGVGFTLGEHLAKSLQAKLILLGRSAFPAPEKWISRKIRKIQE-LEQLGAEI
LVVSADVANEEQMQAVIAKAQQR-FGSINGVIHTAAVV-YAVIQRRVKEMTESVLAPKVRGTLVLSKLLEHVEDFLILCSSVGVVLYTKFGEVSYVAANE
FLDVFSYYNTCKNGTFTVSINWDDWQEVGMSVEAVKNA-VKKYLQNALLPSEGADVFMRILNSSFPQVVSTEDLTTR-----I-----------------
--------KLNDS---------F-----S-KSFESLEVTISKTAHPRP----EL-----SNVYVAPHNELEQTISEIWQQQLGIEKVGIYDNFFELGGHS
LLATQVISRIREAVQIELSLNNLFEEPTVAGISAI-VEK-----------
>tr|A0A0I9VPM5|A0A0I9VPM5_9BURK Polyketide synthase OS=Delftia tsuruhatensis GN=AA671_12420 PE=4 SV=1
--------------------AQVALVFGDGSATAETLVALRAQGIDVVCVEAGAAPACLAPGRHAVRPGERRDCEDLLDAVQAQFGPVDAIYHLWAMDAA
APA--------PLERGFHSVLALAQALEARRTRRLLLVAAGGSEDVTGAEALNPEMAAVFPLCKAIGQECPSIDCRFVDVAQAGS--QARLARQLLDEAR
ALAADTAIALRGAHRWRKTYEPLQWQD------PRLRRQGVYLITGGLGGVGLALARHLAAHWQARLVLVGRTALPARSQWLRQQLLQLLA-LEAEGAQV
LTLAADVADAAQMQAALAQAHQR-FGALHGVVHAAGHADG-MLSTRTRDSVERTFAPKLRGTRLLLDLLGGQADFVLLCSSISSLTA--LGKSDYAAANA
CMDALAALSR-QRAWPVISVDWDAWRDLGMAAGMRIP------EGIGWSGAEAAAVFERIVNGDPHQVISTTDLQQR-----L-----------------
--------GEIDA-----GLVDAL----A-EEAFAEPGSQAGGGHPRP----AL-----QTAYVAAEGELQQALAALWTDMLGIAPVGVDDNLFELGGDS
LLALQILGRVKKRFGVELHPAA-FKAPTVGELAVLVETR-----------
>tr|H3SBB6|H3SBB6_9BACL Polyketide synthase subunit OS=Paenibacillus dendritiformis C454 GN=PDENDC454_04009 PE=4 SV=1
--------------------GSLWVVFSPEDGIIPRLVRMREAGRDVVAVHPSDSFSPLNDWAYRIHPGEAEHYERLLRTLTEAGRAPDRIIHAWLAAEA
GEADIPSDENRALDRGYYSLLALARAIGSCQEELHLAVVTSYMQEVTGDERLQPEQAAAIGACLVIPQEYGHVRCRSIDIADSLRQRQQALAERLHAEIA
APSDDLFVAYRGAHRWVQKYARLPAPAA----GTGLRKHGVYLITGGLGGIGLTLAEHLAKTVQAKLILVGRSGLDGEGAA---KRGALDE-LERYGSEV
LVCKADVCDEARMKQVAAEAVAR-FGAIHGVIHAAGIS-GALIQRRTRETDERALAAKVNGTRVLDRVLAGMRDFLVLCSSLTTALG-GVGQAGYCAANA
YLEAYACRKRAEGGTPVIAIAWDGWQAVGMAAAAEQEIAAIGPDKLTRLPEEGVAVFRQALACRRPQVVSTTDLPLR-----V-----------------
--------HAARAS----TLHS-----------LMDKRDGTGPQAARS----DL-----GTAYAPPEDELEQTMADLWRDYLGLDQVGLHDNFFELGATS
LDIIQMNAKLQRALGREVAVVDMFTHPTIHSLAESLRRA-----------
>tr|A0A0M1NJ26|A0A0M1NJ26_9BACL Polyketide synthase subunit OS=Paenibacillus sp. FJAT-22460 GN=AM231_21035 PE=4 SV=1
--------------------KATWLVFAPEHGVCSRLAGLQQAGHGVISVYPSDSFAKLNDQVYGIDPRQQEHYTRLLQNLKEAGTIPERIVHAWLTEES
IHTETASRSTRILDNGYLSLIALAQAMGTCQDELQLTVVTSGMQEVTGEERLLPEQAAVLGACLVIPQEYGNVRCRSIDIADSLGQRPQALLGRLQAEII
AISADTFVAYRGLNRWVQTYVPIPVPAASEE-NSSLREEGVYLITGGLGGIGMTLAEHLAKTVRAKLVLVSRSGIGDEADWLATQLRMFEE-LEQYGAEV
LVCKADVSNEQQMEQAVARAIDR-FGTIHGVIHAAGTA-GALIQRRTREIEERALTAKVDGTRVLERVLAGRKDFIVLCSSLTSVLG-ALGQAGYCAANA
FLDAYAYRKRALDNTHVVAIDWDGWQTVGMAAAAEQEVAIAGPGKQTRLPEEGIAVFRYALACGLPQVVSTTDLSLR-----L-----------------
--------HAARTS----SLQS-----------LVDGKGGLSRTTPRS----DV-----STPFASPEDELEQTLAELWRDYLGIDQVGLHDNFFELGATS
LDIIQMNSKLQRSLQQEVSVVDMFSHPTIYTLAGLLRRV-----------
>tr|A0A081P0N0|A0A081P0N0_9BACL JamP OS=Paenibacillus sp. MSt1 GN=ET33_11230 PE=4 SV=1
--------------------KRTYLLFHDRYGLAEALSGLKSEGHDVVVVLEGGGFRQVEEDVFTIHPAQGRSYEELLHALAAQKRFPDTVVHLWNVVEP
ESEGIAQRYAWSQQLGLYSLMHLAQAIGMQAKRTDLIVLTGSLQWVAHEQVRSPERATLFGALRVIPQEYAQIRARTVDVSLADLASSGRLIRQLLQEIE
-YGGDFVVAYRGMQRFTQIYEPVKLPEADP---AAFRDGGVYLVTGATSEIGLQLCEEIARTAKVSFVLIGDASFPAAREWTAGIIKRIRA-LEQNGTPL
LHASADLTDEAGLRDIVRQAEQR-FGMIHGVLFAQEPYGG-LIQLGDRERSERVIAPQALGLLALESLLRSHPELMVVFSRTISFTG--VGLMDQCASHH
FVDAFAKWHA-AAGGRTVAVNWGMWQDDVWVRKQTELPADIMQATFGITGAEGLEAIRRIAASGLSQAVSTQSIHDA-----A-----------------
--------GNGWLH----AAGQG-----A----------ASDSRQGRADAYQAG-----DWVQEPPQTEAEHKIAAIWETLFGIPGIGRRQSFFDLGGNS
LLSIQLVARLRQAFHGDIPMDVIFQSPTIAELAESIAQT-----------
>tr|H0U5B0|H0U5B0_BRELA Short chain dehydrogenase family protein OS=Brevibacillus laterosporus GI-9 GN=BLGI_540 PE=4 SV=1
--------------------NQRWLIFQDKQGLGKQVRYAERLGLEVVTVVPGQTFSKIDEKVFTIDIMSEESYQELFKTLDIDNLLPDKIIHMWSIQHT
DEQE---GDEQLEHYGLYSMLYIAKQLGIYQQKMEIIALSNNLQEISNEEILMPVRSTILGPLRVIAQEYPQIKTRYIDVQLTDMLKSDRLLKKVLDEIL
-STSDFMVAIRGTHRFVQKFEQTRLPEKKSH--PSFRDKGIYLITGATQEIGLSVSEEIANTVKASLILIGDPDFPVMEQWIASKIKRIRL-LQQNCEQV
RYHSAHLTDEEEMRQVIRSAEDS-VGRITGIVYAAERFSG-FIPLKSKDSCYQNIAQQVYGPLVLEKLIDHMNEFMLLFSRTFSLTG--VGQMDNCVANV
FLDTFARYQT-AKGIPTIAINWGMWKNDNWIRSQTGMPLEMLQEQYGITAKEGTHVMNRILTSDYSQVVSTQDIHSA-----I-----------------
--------HEFNQY----DTLQ------------------SSTYSHRANDRKQA-----ADTYVAPRDETERKIADIWQDLFGIPAISTKANFFELGGNS
LLSIQLVTRLRNTFYNDIPMDILFQSPTIVELAQAITMS-----------
>tr|I0BLV4|I0BLV4_9BACL JamP OS=Paenibacillus mucilaginosus K02 GN=B2K_22095 PE=4 SV=1
-----------------------YLLFADQGGLAGALR-VVRRGSEVVMVLSGDGHGQDRDGPFVLASDEPQAYEELLRGIRAFGRLPDKIVHLWNTDVH
SEQGLQEDYQAAQRSGLYSLISLAQALGMQGQPVELIAVTSRLLQVAHEPVFLPERATLLGALRVMAQEYGHLRTRVIDVEPGGAARGRMLLGQLANEIG
---SDFVTAYRGPFRYTPSHEEVRLPGVGE---GIFRSGGVYLVTGAAGGMGLPVCEAVAREVQASFILLGDPSFPPPEAWTRDTITRIRA-LEASGSRI
LYASPDLTDEHQTALVLQQAEAR-FGRMDGVLFASEPYS--LIQWKDPARTGETLAPHVLGLAVLSSLLRDR-GFMVLFSRTISVTG--IGQLDLCAYGS
FLDAWARAES-AAGVPVVSISWSMWQEDVWLERMTGIPQGILQTAYGLSAREGVQVIEGLAA--LPQAVSTQDLEKA-----R-----------------
--------HSWASL----HESDGT----V------------SSAAPSP----GG-----PAERTAPRNEVEKTLAGMWETMFGVSGIGIHQNFFELGGNS
LHSIQLVARLRQTFHGGIPMDI-FQSPTIAELAEAVAST-----------
>tr|S9U724|S9U724_PAEAL JamP OS=Paenibacillus alvei TS-15 GN=PAALTS15_16331 PE=4 SV=1
-----------------------YLLLSDNCGVSETLK-LERFGNTVILAHSGD--LNDNDSRLVYNPAQSDSYERLIGNIAYHRRLPNKVIHLGNLDAD
LSNNRYQSYENIQQQGLFSVVSLAQAIGLQFQDVELIVLTGNLLQIAHERVANPERATLVGALRVIPQEYARIGTRLIDVDVADFSFSRRYVRQLAIEIS
---LEFLVAYRGFHRYVQTIEGVRLPLSEQ---ISIRDGGVYFITGADGGIGLLMAEAIAKAVKAKLILIGESPLPDISEWTTKHIRSIRA-LEQNGSEV
WYASASLADEVELKQIIVEAEER-FGSIHGMLIASEPYD--LIQLKDIQETTQRIVPYLVGLSVLASSLNNP-AFLVLFSRTVAITG--AGQMDLCAYNW
YADTFAKHRT-ATGYPTLSVNWSMWQEDVWLDRQKEIPPQMVQKQYGIAATEGIHALERMLA--LPQIVSKQNFQTA-----S-----------------
--------QDWQSI----HTSPVI----I------------NSGAGET----HE-----EVSHSVPRNETEEKIAAIWQTLFGISDIGVHRSFFDLGGNS
LHAIQLVARLRHQFHGDIPMDI-FHHPTVAELAEAVSRS-----------
>tr|A0A0P9E0P6|A0A0P9E0P6_9BACL JamP OS=Paenibacillus sp. A3 GN=QJ48_07450 PE=4 SV=1
--------------------KRTYLLFHDRHGLGEALSGLKNKGHDVVAVLEGGGFRQVEEDVFTVHPAQGRSYEELLHALAAQQRFPDAVVHLWNVAEP
ESEEIAQRYARSQQLGLYSLMHLAQAIGMQAKPTELIALTGSLQWVAHEQVRSPERATLLGALRVIPQEYAQIRARAIDVSLADLASSGRLTRQLLQEIE
-HGEDFIVAYRGMQRFTQLYEAVKLPEADP---AAFRDGGVYLVTGATSEIGLQLCEEIARTAKVSFVLIGEASFPGAREWTAKIIKRIHS-LEQNGSPL
LYASADLTDEAGLRDIVRQAERR-FGAIHGVLFAQEPYGG-LIQLGDRERSERIIAPQALGLLVLVSLLRSHPELMIVFSRTISFTG--IGLMDQCASHH
FVDAFAKWHA-AAGGRTVSVNWGMWQDDVWVRKQTELPANVMQAQFGITGAEGLEAIRRIAASWLSQAVSTQSIHDA-----V-----------------
--------GSGWLH----AAGHA----------------ASDSRNSRTDTHRDG-----EAPQEPPQTEAEQKIAAIWETLFGIPGIGRGQSFFDLGGNS
LLSIQLVARLRQAFHGDIPMDVIFQSPTIAELAESIAQT-----------
>tr|A0A0C2LKV2|A0A0C2LKV2_9CYAN Polyketide synthase OS=Scytonema tolypothrichoides VB-61278 GN=SD80_11160 PE=4 SV=1
--------------------NERWLLFIDECGVGSELGRLEQSGKNVIVVKVGHQFTKLSEGIYVINPQNCDDYDVLFQELIALGKTPHNIAYCWSISTL
NT------LEQNEFLEFKILLFLTQSLNNQTNRLQIWVISNKIQEVNGNETLSPEKATVLGLCKVIPQEYSNITCRSIDVVLTNRRCDSHIIDQIINEFR
AKSSELVVAYRDRYRWVQTFESVRLESVVEE-KTPLRKQGVYLFCGGLESLGVVLAQYLVKTLQAKLIFIEEWAFPEKHEYVSRKIQKLQK-LGDLGAEV
LIVRADTTNYEQMYQSLA--PEK-IGEIHGVIYSTGRT-ENSIPEIGQTELEKLLDSQRQNLTVLEQVLEKRKDFCIIFSSLSSILG-GFGLALYSGVNQ
LIDTFSQRHNQTRSLPWIVINWDKLQLNTTQEQK-----TLSGMELAITETESVEVFKRILSLRGTQVVSTVDLKAR-----C-----------------
--------ERT-----------FHL--DSKLS--KFSQVNSSSSYSRP----NL-----SNSYVAPTNELEEQITEIWQEVLGIAQVGIYDNFYELGGDS
LIATQLVSRLRAKFPVELPLRDLLVQAMIPAKQAEMIEQ-----------
>tr|A0A0M4T2E0|A0A0M4T2E0_9NOSO PscL OS=Nostoc piscinale CENA21 GN=pscL PE=4 SV=1
--------------------KSIWLLFVDDLGVGEQILKLKNQGNTVVTVHQGDEFQKISTTSYQINPYSNSDYELLIQELLSSGIQPENIAYFWSLSQI
EN------SQPDKYLECKSLLSLIQSISKLKHHLQIKVITNNILEVNGNEKLNPEKSTILGLCQVISQEYPNITCQCIDIVFNGDR-NNQIIDQISNELI
STSLDNVIAYRDRHRWVQTFTPSHLDAIVDE-NTPFRNRGTYLFAGGLDNLEFLLAEYLTKTCQAKLIFIESSQFPKQENFISQKIQHFIA-LEEIGAAV
LLLRADKTNYEQMHQILA---KN-VEQINGVIYATGIK-EQSLPEITVAELENILKSQRHQITILEKVLQNYDDFCCIFSSLTSILG-GFGLCLDAAVYQ
LLDSFGNQHNQNNSCPWYIINWDNIQLHTTPEST-----ITSGTTLAITATAIIEVFQRVLAIQGTQMISPVDINVK-----K-----------------
--------TQIIN---------R-----N-SLETQSKQLDSSPRYSRP----SL-----NNSYIAPTNELEKQITEIWQEVLGIKEIGIYDNFYELGGDS
LIATQLVSRLRAKFPVELPLRDLLVEAMIPMKQAEIIEQ-----------
>tr|K9QFB1|K9QFB1_9NOSO 6-deoxyerythronolide-B synthase OS=Nostoc sp. PCC 7107 GN=Nos7107_3486 PE=4 SV=1
--------------------QEDWLFFVDDLGIGEQLAVLINQGKNVINVKRGEQFKQIDNSNYIINLYIKEDYDLLLKEIISSGGNIQNIVYVWSLDYL
NE---------SKYLEFNSLLFLTQSIGKLS-DLQLWVISNNIQQVNGYEQLEPEKATILGLCKVISQEYSHITCRCVDIDLTNRQGYYESIAQLANELT
SVSSDLVVAYRNSYRWVQTFEPIRVEAILEE-KTPLRQQGVYLFPGGLGDIEVAIAQYLATNFQAKIIFIEDENFPEKDDFVSRKIERLLV-LEQLDPTV
LVIRIDATNFS---------WEK-IGEINGVIYKTGIK-EDSISEIQDRESTDLFNFQHHHIRLLTQVLQNQNDFCVVFSSVSPILG-GCGLSLDAAASY
FLDTFINQHNCKNSLPWYIINWDKFNQAQQ---------T---SELAISAKEAVEVFQRIFTLEGTQVISPVDINTR-----N-----------------
--------NQIFN---------PH----FFTN-SKSFELDSSSRYSRP----NL-----SNAYVAPTNNLEQQITEIWQEVLGITEIGIYDNFYELGGDS
LIATQLVSRLRAKFPVELPLRDLLLQAMIPAKQAEMIEE-----------
>tr|A0A0D6YL79|A0A0D6YL79_MASLA Polyketide synthase OS=Mastigocladus laminosus UU774 GN=SP67_06205 PE=4 SV=1
--------------------QTKWLFFVDDLGVSEELIALENQDNNIIIVKTGEKFEKKDECIYTINPCIDQDYHIFFKELIALGKFPKNIAYFWSLNNY
NN------YHSENYLEFQSLLFISQSLSKLDQSLQLWVVSNHIQEVDGNEIINPEKATVLGLCQVISQEYPQITCRSIDIALTNYLYESKIIDQLLNEFT
AVSSDLVVAYRGSHRWVQTFEPVHLTSAVEE-KLPLKKHGVYLFFGGLDSIEVVLAEYLIKNFQAKLIFIEDLDFPEQYDFISCKIQQLQV-LENLSADI
LVIRADKTDEQQIRQIFL--SEN-IEQINGVISSTGIK-EKSIPEIGKIESKNLFDFQRRQITVLAQLLENINDFCIVFSSLSSILG-GFGLGLYSAANH
LIDTLINQHNQNNYLPWYTIKCDKIQLNFTPKSD-----TISGEKLAINPTETIEVFKRILSLDKTQIVSTVDIKTR-----H-----------------
--------NHA-----------FNL--DYPAS--KYSQLYLSPRYSRP----QL-----SNSYIAPTSELEKQITQIWQDVLGIAEVGIYDNFYELGGDS
LIATQLVSRLRAKFPIDLPLRDLLLKAMIPAKQAEMIEQ-----------
>tr|M4T9Q7|M4T9Q7_9NOSO Polyketide synthase OS=Nostoc sp. 'Peltigera membranacea cyanobiont' PE=4 SV=1
--------------------DKEWLLFVDDCGVGVQLIRLEQHDKNVIVVEKGQEFRKLREGVYTINPQNRDDYDVLFKELILLGRIPQNIAYLWSLNTF
EN------RQLSKYLEFQSLLFLTQTIGKERDRLQIWLISNQIQEVNGNETLDPEKATVLGLCKVIPQEYPNITCRNLDFVLTNRRFDSYIVDQIINEFI
ALSPDLVVAYRDRYRWIQTFDSVHLSAG-AD-KNILRKEGVYLFPGGLESFAVVLAGYLAKTLQTKLIFIEDSPFPENDEYVSRKIQRILI-LEELGAEV
LVMRADPTNYEQMHQILG--SDN-IGQIHGVISSIGIT-ENSIAEIQKTELEKLLDTQIHKITILEKVLHNQKDFCIILSSLSSVLG-GFGLALYSGVNQ
LIDTFTQRHNQTTYFPWKIINWDKLQLNATQEEK-----ILSGVELAITETESIEVFKRVFSLAGTQVISTLDFKAR-----C-----------------
--------EYASR-----MLRDRTFKGDSIAA--KFSQLDSSSHYSRP----NL-----SNSYVAPTNELEKQIVEIWQEVLAITEVGIYDNFYELGGDS
LIATQLVSRLRAKFPVELPLRDLLLQATIPAKQAETIEQ-----------
>tr|K9WB71|K9WB71_9CYAN Polyketide synthase family protein OS=Microcoleus sp. PCC 7113 GN=Mic7113_1745 PE=4 SV=1
--------------------QEQWLLFVDEWGVGSQLVKLEQNGKNVLVVKVGEKFTQLSEGVYAINPQNRDDYEALFQELIAQDKIPHNIAHLWSLNTF
DN------RQLGKYLEFNSLLFLTQSLGKLNEYLQIWVVSNQTQEVSGNETLVPEKATVLGLCKVIPQEYPNITCRSIDVALTNRQCDSPIIDQILGEFT
ALSSDLVVAYRDRYRWVQTFEPMRLESVIEE-KTRLRQQGVYLFPGGLESLGVVIAEYLAKTLQAKLIFIEDSAFPGRDEYVSRKIRKLLV-LDELGAEV
LVVRADATNYDQMHQSLA--PEK-VGQIHGVIYSTGIT-ENSISEIDSTTLEKQLDYQRHKITVLEQIIQNKNSFCIIFSYLSSILG-GFGLALYSGVNQ
LTDTFTQRQNQTKCPPWLSINWDKLQLNATQEQT-----VFSGVELAITEIESVEVFKRILSLGGTQVVSTVDLKTR-----C-----------------
--------DRLWRG----TQRHHTFNLDSLPS--KHSQADLSSRYSRP----NL-----SNSYVAPTNELEKQIAEIWQEVLGIAQVGIYDNFYELGGDS
LIATQLVSRLRTKFPVELPLRDLLLQAMIPVKQAEMIEQ-----------
>tr|G6G0G1|G6G0G1_9CYAN 6-deoxyerythronolide-B synthase OS=Fischerella sp. JSC-11 GN=FJSC11DRAFT_4610 PE=4 SV=1
--------------------KSCILLFVDECGLGNKLLQLQQQNYDVISVKVAHNFTRLNESEYTLNPQQPDDYDALIQELFKQQKLPKKIVHLWSVTPG
CQQQDFEKVEQAQTRGFYSLLFLAKALARQNDDFEITVISNHLQPVTPTELVSPEKATLLGAIKVIPQEYANITCRSIDVIIPANGQEQKLVESLLGELS
ISSCEKVIAYRGGNRWIQCFEPVRLEQVKSN-TPRLKQGGVYLITGGLGGIGLVLAEYLATQVKAKLVLIGRRAFPNQQEWISCKIRKLQQ-LQQLGAEV
LVLAADVTDLQQMQQAIASAYST-FGQLNGVFHAAGIV-GKAIDKITKTDCEQQFQAKVHGLIVLEKVLKNTQDFCLLLSSLSSVLG-GLGFVAYSAANN
FMDTFVHQHNQNHPVSWISVSWDSWQLETENQQS-----TSSVSEFAFNAQEGVEALQRILNYSFNHVVSTGELQAR-----I-----------------
--------DQWID-------------------LKSFPQTNLLSLHPRP----DL-----QNPYVPLTNEIEQKIANIWQEVLGIKDVGLYDNFFELGGDS
LLIIQVRNKLLKTLNKNLSIADLFEYSTISALAEYLGEK-----------
>tr|A0A0M8RR76|A0A0M8RR76_STRRM Uncharacterized protein OS=Streptomyces rimosus subsp. pseudoverticillatus GN=ADK70_04940 PE=4 SV=1
--------------------ADPVLLFADE---AARL---AAHAGEVLTVRTGTAYGRD---TWTLRPDSEEDHARLVADLLAEERLPDRVLHAWSTAPL
PAERGRERFETAQRHGLYSLIALVKALSEHTKPLQLDLISAGAYAVPAEPEPAAELVPLAVAARVIGQEHGNIGSRHFDLPATVDE-----LRTLAAELA
GQRPEVATTLRGATRWIADLEPVRADWTAK---SRLREDGVYLITGGLGEIGATIAKWLRECPGVRLALLTRDPLPDRAEWTSLRIQRLRA-LEDGGGEP
LLVHADVAGEDALRAAVDQVTAH-FGALHGVVHAAGLPSQ-AITAASAEQCEWHFVPKAHGQIALEKVLSGHDDFVLLLSSLAGVLG--LRLLGYGAANH
FMDAAAERRG-LDRTVWISAAWDVWQHHDEKRAI-----SASMDDKAIQPEEGLEAIRRLLTLRVSHVVSTWDIGHR-----L-----------------
--------DQWVRD----ERIARP---TA-------------GAAAAV-----A-----DAE---AADDLVGQVARLVRGALGAEDMPLDGDIFEFGGDS
LLIVRLLSDLRDQFSVEVPLAD-LGEPTPAALARLVQER-----------
>tr|A0A0N1G4G9|A0A0N1G4G9_9ACTN 6-deoxyerythronolide-B synthase OS=Actinobacteria bacterium OK074 GN=OK074_3106 PE=4 SV=1
--------------------GEPVLLFADA---AARL---TEHAGEVFTVAAGDAYARD---TWTVRPDSEEDHGRLVADLLAEDRLPARVVHAWAAGQL
PAERGIERFEQAQRTGLYSLIALVKALSAQTRPLQLDVVSAGAYAVPAEPEPASELVTLGVAARVVGQEHGNIGSRHFDLPAPVDE-----LRTLAAELT
GFRPEVAVTLRGATRWTADMAPVRADWTAT---SRLRERGVYLITGGLGEIGSTIARWLHEC-GARLALLTRDALPPREGWTALRIVRLRA-LEAAGAEP
FLVNADVADEAGLRAAVERVEAH-FGALDGVVHAAGLPSQ-AITAASVEQCQWHFVPKAHGQIVLEKVLADHPDFCLLLSSLAGVLG--LRLLGYGAANH
FMDAAAERRG-LDRTVWISAAWDVWQHHDEKRAL-----SASMDDKAIQPDEGLEVIRRLLTLRISHVVSTWDIGHR-----L-----------------
--------DQWVRD----DRVARP---SA-------------GVAAEP-----D-----DAAAGLGDRDLTEQVTRMVRHSLGTEDITPDGDIFEFGGDS
LLIVKLLSDVREQFSVEVPLAD-LGEPTSRALAALVQER-----------
>tr|X0N2L4|X0N2L4_STRA9 Polyketide synthase OS=Streptomyces albulus PD-1 GN=P354_30000 PE=4 SV=1
--------------------ADPVLLFADA---AARL---TRHAGEVLTVTAGTDYARD---TWTIRPDSEEDHARLVRDLLAEERLPDRIVHAWSTAPL
PAERGKERFEQAQRHGVYSLIALVKAVSAHTHPLQLDLISAGAYALPAEPEPAAELAPLAVAARVIGQEHGNIGSRHFDLPGTPDD-----LRTLAAELA
GRRPEVATTLRGATRWIADLEPVRADWTAK---SRLRDGGVYLITGGLGEIGSTLAHWLRECPGARLALLTRDPLPPRETWTALRMTRLRA-LAAEGPEP
LLVHADVADEDALRTAVEQVTGH-FGALDGVVHAAGLPSQ-AITAASVEQCQWHFAPKAHGQIALEKVLADHPDFCLLLSSLAGVLG--LRLLGYGAANH
FMDVAAERRG-LDRTVWISAAWDVWQHHDEKRAI-----SASMDDKAIQPEEGLEAVRRLLTLRVSHVVSTWDVAHR-----L-----------------
--------DQWVRD----ERIARP---TT-------------GGTAAA-----A-----ADG-AGGADDLTEQVARLVRGALGREDMPLDGDIFEFGGDS
LLIVRLLSDVRDQFSAEVPLAD-LGEPTPRALARFVQER-----------
>tr|A9FNK2|A9FNK2_SORC5 Polyketide synthase type I OS=Sorangium cellulosum (strain So ce56) GN=sce8261 PE=4 SV=1
--------------------EAHWLVFTDEEAIGSRLVRIERAGRRVTRVRSGERFERAAERSFTLRLDQPEDYAALLRDLGASAGPPTRVVHAFSLGDP
RGPHDPGAFREAQRRGSASLLWLARALGQQ---AHLVALASGLHDLTGREALRPEHAPLLGVCRSVPLEYPHLRCRVIDLEAPVPD-ADRVVERILAEAR
SDAADTVAAYRGHHRWAPAVEPVALRPAQA--APLLRERGVYLITGGLGGIGLRLADHLARTARARLILTGRSAPT------DEQRARLLA-LEKAGAEV
IALRADAADASQMRAAAREAIDR-FGALHGVIHAAGVAA-G---RLTADALDAELSPKALGALAIDEIARALKDFVLLCSSITALSG-GLAHAGYAAANA
FLDAYAQAR--RAGPYTVSVNLDRWRNVGMAARAEA---RLDVIRNGMSPEEGLQVFHRVLSQALPQVVSVRPLHGL-----P-----------------
--------SDDEGA----ALARRL---GA-G-GAAAA-----RSHEPP----RR-----AGAAALSPEAITAQVTAIWARAFGIDPIDPRKDFFALGGES
LLALQILNRVREAFQVEVPLRAFFERPTVAALAERIHEA-----------
>tr|S4YFD6|S4YFD6_SORCE Uncharacterized protein OS=Sorangium cellulosum So0157-2 GN=SCE1572_48225 PE=4 SV=1
--------------------GAHWVVFADEAEIAPRIVRLERAGRRVTRVRSGERFARPAERAFTLRPDQPEDYAALARELGADAGRPARIIHAFSLDG-
----DTGAFQDAQRRGSISLLWLARTLSKL---AHLIALACGLHDLTGREALRPEHATLLGICRSIPLEYPHVRCRVIDLEAAAPD-VDPIAARILAEAR
SDAGDPVVAYRGPHRWAPAVEPVPLKPAQG--AALLRERGVYLITGGLGGVGLWLSDYLARTVRARLILTGRSAPT------DEQRLRLTA-LEQAGAEV
VTVRADVTDAAQMRAAAREALAR-FGALHGVIHAAGVAG-G---RLSADALHAELAPKALGAMALDEIARSLRDFVLLCSSVTALSG-GLARAGYAAANA
FLDAFAQAR--RPGPYTVSVDLDRWRNVGMAARAEA---RLDVILDGMRPEEGQQAFHRVLSQALPQVVSARPLQGL-----P-----------------
--------SDDEGA----ALARRL---GA-G-DAAADAAAAAGRDEPP----RR-----AGAAALSPEAVTAEVTAIWSRAFGLDPLDPKKDFFELGGES
LLALQILNRVRETFQVELSLRDFFERPTVAAVAQRIQAA-----------
>tr|A9KE00|A9KE00_COXBN Polyketide synthase OS=Coxiella burnetii (strain Dugway 5J108-111) GN=CBUD_0834 PE=4 SV=1
-----------------------WIIFANQSVLCEKTC-LLSMGENIIKIFPGEEII--TYNTFTINPAEKSHYEEVLRKSVSTDEAHYVILHFWGVDSS
EIKS-NLLNSTELYQGLYSGIFIAQALNRIHASIFWGMVTTHLYSVLGNEKINPLKSTVLSLSRVLPLENSNIRMCQIDVDSLMNEYANEVISQVVKNLS
C--VANTIVLRHQKRWKPTYQEINVTEFSN---ITIDPQGTYLITGGLGGMGLAIAKWLSKNSGITILLLSRSVFPAQNSWISEKIKQLKK-IVRKGCQV
EILKGDIADYRQIKVLLSKVEKQ-TGPIRGIFHLAGISG--LTALKNIETVQAVLQPKIQGTWVLARLFRKKVDFFVSASSLTAIAG--VGQIDYCAANI
FLDHFLEQNPFKYCERLLTINWNAWRSVGMAANVAGA--KVLYAGNSVTPEQGIKVLNTFLR--YRQVVSRYQPEEE-----I-----------------
--------KRIKRM----FQPEEKI--DL----------------SAA----NR-----MKPKESNQLNVFDVMGQTWKAVLGVSKINKTDTFYDCGGDS
LTMIQLIAALEKHFGITIILQD-IRETSFGGMVRFVEAL-----------
>tr|A0A0C1T7N1|A0A0C1T7N1_9CYAN Uncharacterized protein OS=Scytonema millei VB511283 GN=QH73_41305 PE=4 SV=1
--------------------QSCTLVFIDECGLGEALVRLR-QGQMAIAVRVGSQFGQIEENVFAVNPQQAQDYEALLQALHARQQFPDSMIHLWTLTPH
SQIGDVEIFERVQVRGFYSLLFLAQALGKQGDRLQLIAISNHLHSVTAEEILCPEKATIMAALKAIGQEYPHVSCRSIDVMIPD---AEKFVERLLEELT
DASADVAIAYRRGQRWVQAFESVKLPKTNT---ALLRTGGVYLITGGLGNIGLVLAEYLAQSVKAKLILTGRSAFPAKDEWINGKIRKIQQ-LEALGAEV
MVAAADVANINQMQAVIERAELQ-FGRLNGVIHAAGVL-ERTIEKIETINCERQFQSKVYGLFVLEKVLQGREDFCLLMSSLSSVLG-GLGSVAYAAANL
FMDAFVHQQKQNNSIPWIGVNWDIWQFKNNKNIF-----TSSLAEFAIAPEEGIDALQRILSQDFEQVVSTGDLQSR-----I-----------------
--------ERSIQV----K-----------HSEPDIPQESLSSAYSRP----NL-----PNCYVAPRDRLEQTIANLWQQLFGIEQLGIHDNFFDLGGES
INGMTFINQFQKQLGQIVHISAIFEAPTVAEFAAYLQKK-----------
>tr|A3INX2|A3INX2_9CHRO Polyketide synthase type I OS=Cyanothece sp. CCY0110 GN=CY0110_07434 PE=4 SV=1
--------------------NDCWLIFMDEYGLGNALIRLKSQQQEVIQVKMGTDYQKINNHQYIINPEVKEHYQPLVEQLLASHKNP-IIAHLWTVNSV
------QCFEESQALGYQSIIYLTQAIGQRMASLSIGVVSSQIQQVTGEEILCPEKATVLGPVKVIPLEYLNLTCRNIDLVISDRC-EQPFVDQLITELT
LSSSDSFVAYRGNYRWIENYEKITLEKNEK---SRLRSEGVYLITGGTGGIGLALAEYLAKTVQAKLVLLSRSANPNNQE-------SINK-LEQLGSEV
LVLQADVSNEQQMQEAFNKINHK-FGCLNGIIHAAGLL-KGEQ---NSDLSDPVFAAKVKGTLVLDKMCKNIQDFLYLWSSVGTILG-EFGQVDYDAANI
FLDKFVNQK---SDYFTAAINWDLWREIGLASNLSW--YKNENLKQGMATEEGIEAFSRILAEDKSQIVATRGIETM-----I-----------------
--------EIFKPS----KSQ---------SLKQQETTSKNHSAYPRP----NL-----STSYVAPRNKKEEIISEIWKTILGIEKIGIYDNFFELGGHS
LLATQVTSRIQETLNVQITVRELFEHQIIAKLAEFLENS-----------
>tr|K9ZNK8|K9ZNK8_ANACC 6-deoxyerythronolide-B synthase OS=Anabaena cylindrica (strain ATCC 27899 / PCC 7122) GN=Anacy_5461 PE=4 SV=1
--------------------NVSWLVFVDNTGFGDAFCRLKTHQHKVIQVKIGNCFSQINEQVYTINPQIREDYEKLFQKISQLGKVP-LIAHLWSLNPH
------ESFEKSQELGLYSLLNLSYVIAKQTESLKIGVISSDIQIVIGDENIHPEKATVLGGCKVIPQEQPNITCRSIDIVISK-L-ENELIDKLIVEIV
ADTSEDVIAYRNNYRWVQTFAAIPLEKTAT---KQLRQKGVYLIVGGLGGLGLGIAEYLAKTAQAKLALIGRSTLPEKSAWSSQKIRKLQE-IEKLGAEV
LVLSADVADEVQMRSAVTQINAK-FGAIHGVIHAAGVR-GGLK---TSAMIKAVFAPKVQGTLVLDTIFKDVPDFLVFWSSIAAFTG-GYGNVDYVAAHT
FLDRFAQCSSL----PTITINWNAWQEAGMAIQLQEKY-KLEILKNGITLEEGIEAFNRILVSGLSQVVTPQNMQET-----M-----------------
--------TQYANM----G-----------VFADKLAKTTVKANYPRP----HL-----SNSYVLPRNQIEQTIADIWQEVIGIEKVGIYDNFFDLGGDS
LIGVRVINSIQEEFHIQLSTVSIFEAPTVSQLAQLLNPE-----------
>tr|K9PIC3|K9PIC3_9CYAN 6-deoxyerythronolide-B synthase OS=Calothrix sp. PCC 7507 GN=Cal7507_2758 PE=4 SV=1
--------------------KRCWLVFVDESGLGSSMVRLE-QGHSVIQVKIGGEFSRNSDRIYTINPQQQKHYEQLLAEILVSESIS-YIAHLWSISFT
-----------EQDMGFYSLLYLAQAIGNQTNSIHIGVVSSNIQDVTGTEIIYPEKATLLGACKVIPQEYANITCCSIDVVPAS-F-ENQ----IITEIA
AQSTDTVVAYRGNYRWLPTYTAVRLEKAQK---IPLQPKGVYLITGGLGGIGLAIAQYLAETVQAKLVLVSRSHLPSKDEWTTSKIRQVQV-LENLGAEV
LVLSADVTNAAQMQMVAERSQQV-FGHIQGIFHAAGVA-GGLK---TPEMAANVMAPKVTGTLVLEETFKDNNDFLVLFSSLSSIVG-GAGQIDYCAANI
FLDVFASYKASKTKTFTTSINWDAWQEIGMGVKTTEIPDVLETLRTGISSKDGLDSLSRILQSGLNRVVSTKDLQTV-----L-----------------
--------KQKHD-----G-----------IHE----ELNPQKIQNSP----SA-----HERYLAPRNEIEQQIAQIWQEQLGIEVVGVNDNFFELGGHS
LLAVRLVSRLREIYQVELSLRTLLEAPTIAEVANAITEN-----------
>tr|A0A068J4P2|A0A068J4P2_9BACT Putative NRPS/PKS hybrid synthase module B7B OS=uncultured bacterium PE=4 SV=1
--------------------AGRWLIFSDGGRLAENIILLADGEREIIVVTPGDSFTATGAGEYCLQPGSHDDMAALFAALRQRDAVPETILHLWSAAPA
ATPD-DDGSGAALEKGFYTLLHLAQVLSERAEPLELVVVACGTHSVNGDETLYPQHAALSGLCRVIPQEQDRVRCRSIDIEASNDGDQGKIARRIIAELS
HAATDPVVALRNSGRWIPEFEAVTLDETAVP-PPGLRQNGVYLITGGLGNIGLQLGQYLARAVSARLVLLGRSELGPRSDWLGRKILAVRA-LEDAGAEV
LVLSADVADAAQMREAIEQVSAK-FGQIDGVIHAAGAT-QDMLRDLDRAACERHFLPKIRGVQVLDQALEGHSDFCILMSSLASLLG-GLRFAAYASANA
FLDAFARSRAAGEGLSWLSVNWDGWQFGDPDSSDN----ST-VAGLA-TASEGVDVFSRLLQVKIPRLVSTSDLQAR-----L-----------------
--------DQWTRP----QQKAAV----A-----DGLSGASSAGQSGP------------------DEGIEKRLCAIWSGLLGVDGIAVDDNFFDLGGDS
LLALQVTSRLRESRIADLSTATVLESPTIAELTRRILKQ-----------
>tr|B1WWV9|B1WWV9_CYAA5 Polyketide synthase type I OS=Cyanothece sp. (strain ATCC 51142) GN=cce_3080 PE=4 SV=1
--------------------PQNWLILTDESKLANALINLQKYQQTVITVTIGEEFIEIDENQYSINPQNAENYQKLWQNLTQ---KPQRILNLWPMKEI
KTF------EQCQDLGFYSLVYLSQTIAQQ-EAIKMTVMTEGLQDVIGTETLNPGKATILGACKVIPQECPHIHCQTIDITAHN-----LSINSLLTELL
T-TKDAVVAYRGSHRWVQTFEPLPLAEVET---IPLKQEGVYLIVGDFEGLGLVYAQWLRQTVNAKLVLIGRKDLPPQEQWITRCVRQLQA-LGTGGTEF
LFFNADLTDKKQIKAIIAQATEK-LGNINGVIHAGTMGDA-PLPHLTPKECDRQWKTKVKGLLVLEEVLQGQPDFYLLQSSLSSVVG--LGFAAYAAANT
FMDTLATQRNQTGTIPWYSVNWDACQLDAMPQE------KTALLDLAMTPQEVWEVSRRIFACAHPQIVSPGNLSTR-----M-----------------
--------NQEMRH----STPEDP----E----AL-------SSYHRP----TL-----NTPYEAPRNAIEKQVAEALQELLGIETVGIHDNFFELGGHS
LLAIQAVSRLREEFQVELPMRKLFESPTVAGIAKLIEEN-----------
>tr|T2JPK0|T2JPK0_CROWT Malonyl CoA-acyl carrier protein transacylase OS=Crocosphaera watsonii WH 0402 GN=CWATWH0402_2477 PE=4 SV=1
--------------------SQNCLILTDESELSNALISLQKSNQNIVTVSIGDEFTQIAEKQYIINPKSAEDYQKLWKSLPQ---KPHKILNLWLNKKV
EIF------EQCQDLGFYSLVYLSQTIGQQ-ETVTMTAIAEGLHDVIGTETLNPGKATILGASKVISQEFPNINCQTIDITAHN-----ISINSLLTELL
T-TEDTVVAYRGHHRWVQTFEPLPLAEAEK---IPLKQKGIYLIAGNFEGLGLVYAQWLKQTINAKLVLIGPKNLPPQTEWVTRCVRQMQA-LGTGGTEF
LFFNADLSNKEQVKEIIDQTIEK-FGKIDGVIHAGTMGDS-PLPRLTPEECDRQWKTKIKGLLVLEEVLQGHTDFYLLQSSLSSVVG--LGFAAYAAANT
FMDTFATQRNQTGSTPWYTLNWDACQLDDVSPE------KTALLDLAMTPQEVWDVSGRILAHAHPQIVSPGDLSTR-----M-----------------
--------NQEIVP----PTFADR----E----AL-------SSYQRP----SL-----NTPYEAPRNDIEEQVAEALQELLGIEKVGINDNFFELGGHS
LLAIQAISRLREEFQVELPMRKLFESPTVAGIAKLIEEN-----------
>tr|L8LWI8|L8LWI8_9CYAN Polyketide synthase family protein OS=Xenococcus sp. PCC 7305 GN=Xen7305DRAFT_00002070 PE=4 SV=1
--------------------GSRYLVFVDELGIGDRIIKLRDNGQTAIAVSQGENFSQN-KDTYTINPNNPEDYQKLIQDLVTSGKIPQKIIHLWNIPPQ
IPNP---NPQLPNSLDFWSLIYLAQAIEQNQQKTQILVGTNNLYDIIGDETLAYEQADILGAIKVIPQEYSEIDARQIDLAISETD--DYNIEQLITEFT
TDTKDKIVAYRQNRRWVQTFESISLTKNSPE-QSKLKPQGIYLITGGMGGIGLALAEHLARTVQAKLILLGRSEFPNREHWTSQKICQLKN-LETLGAEV
LPVTADVCERDAMEQAIALACNR-FGTINGVIHGAGVA-GGLK---TPAIAETVFAPKVTGTLVLNQVLQTIDDFLVLCSSLTSIV-GGFGQADYCSANA
FLDILAHHNR--NNCPTVAINWDAWQEVGMAKNTTV---PADNLQQGMLSGEAIEVFERAL-ASLSQVVSTQDLPTV-----I-----------------
--------EQNNNF----LTQY-------M-----AQPENSASSDSRS----LE-----RKNYVAPSNEIEKTIAKILQEVIGLKGIGIHDNFFELGGHS
LLAVQVTAQLREIFQVDLSLQTLFEAPTIAQLANIIINQ-----------
>tr|K9XVV6|K9XVV6_STAC7 6-deoxyerythronolide-B synthase OS=Stanieria cyanosphaera (strain ATCC 29371 / PCC 7437) GN=Sta7437_2670 PE=4 SV=1
--------------------E-SYLIFVDSSGIGKQLVQLRQNGTEVSTVYCGDKFSQH-DHNYKINPTNPEDYHSLLKAISLTSNLPTKIIHLWSLSPH
L----------PYNQSFYSLIYLAQALEQQKHKIKIVVGTNSLYDIIGNETLFYEQATVLGALKVIPQEYTYLDCRQVDLVIPESE-------NLITEFT
TDTKDKIVAYRGNRRWVQTFEPIPLAKNTQE-KSKLRQEGVYLITGGMGGVGLVLAEYLARTVQAKLILLGRSQLPSQETWISQKITKIRD-LEALGAEV
LTLTADICDRAQMQNAIAVALKR-FGKINGVIHAAGVA-GGLK---TPEIAESVFAPKVTGTLVLNQVLAGIDDFLVLCSSLSSVV-GGFGQADYSGANA
FLDVFARCNH--SNCHTVAINWDAWQEVGMAVNTEI---PPDNLKNGLLSAEAVEVFERAL-VSLAQVVSTQDLATA-----I-----------------
--------EQNNNF----LATY-------T-----TQPDSNYQ---------HL-----SKNYVAPSNKIEKTIAKIWQEVIGFEKIGIHDNFFELGGHS
LLAVQVTSRLREAFNLDLPLRTLFEAPTIAQLADAIADQ-----------
>tr|M5PC46|M5PC46_9BACI Polyketide synthase PksE OS=Bacillus sonorensis L12 GN=BSONL12_21789 PE=4 SV=1
--------------------HGKWLIFADR--VGQSIAILADRDEQFVMVYPGEQ--F----EYRIQPSDPEDYRKLVLE-GGNGSHLKGIIHLWNLDAA
DMQD---TLRQAELLG---VLHVVQA----KTAPRLWVMTRNAQNIVNDGAIHVLQAPVWGLGKVINLEHRDIKGGLIDLDPLPD---------------
--------------------RYVARLIERK---PVFRFDGSYLITGGFGALGLLVARWL-ERGARHLILMGRKPLPERHAWPMDRVKAVKE-LEKLGAAV
HVAAVDVNDEQSLSDYLKAYKQESWPEIRGVIHSAGAALPQILLQVQQKDFSRVMEPKTIGAWNLHKQFEP--DFFVLFSSIASLVA--TGQGSYSAANA
FMDGLAHYRR-AKGLPALSINWGPWGQAGMAT-Q-----LDGFY--PMTNDQGLEAFGHLLG--VAQAVV-GDWPL------V-----------------
--------VKANFG----GNQ-PSMLADKDPA---------AAGQSGDPL-TALLA--LKDP--DARRFIISHLQDIAAGVLSL-KLSPEQSLGNYGLDS
MMAIELKNRIDDHFHI--NIVDLLKGPSIVRLSEQISSR-----------
>tr|E0I6D4|E0I6D4_9BACL 6-deoxyerythronolide-B synthase OS=Paenibacillus curdlanolyticus YK9 GN=PaecuDRAFT_1206 PE=4 SV=1
--------------------DGNWLIFMDA--VGQSLMRLHAQGERCIAIWASESASF----TYAIDPNQPAHFEQLFNG-FSSKAACRGIVHLWSLDAE
H--A---SLLASEALT---ALHIVQT----HSKPQLWLVTREAQST-DVTALNVSQSTLWGLARSLGQEHGDIWGGIIDLDKQQA---------------
--------------------RYVARLLPVE---LAFRSDASYIITGGLGDLGQLVAKWM-KQGARRLILIGRTALPPRSAWAQRRIAAVRQ-LERLGASV
HVASLDIAEESELHAFLHQFEREGWPAIRGVIHAAGVLQSKLVTQMSADDFRTVLRPKALGAWNLHHYFKE--DFFAMFSSIASVVV--AGQGSYASANS
FLDALAHHRR-SLGLPAYSINWGPWEELGMGT-------IEGFT--PIQPDQGLEALEQILG--LPQVVV-ADWPT------V-----------------
--------QERNYP----MGASPVLLDAQAAT---------AVALTGKIT-DLLQQ--ETEP--EKRQLIVGYVQQMSAKVLRL-QLQQDQSLIDYGLDS
MMAIELKNQMEKDLSV--NIADLLRGSTVAKLSEKIGQQ-----------
>tr|A0A074LQG4|A0A074LQG4_9BACL Uncharacterized protein OS=Tumebacillus flagellatus GN=EL26_14285 PE=4 SV=1
--------------------PGLWVVFQDA--VGRELASLLKRGEKVLQVERGDS--W----AARLNPTSADDYRELMQW-AAQGVACKGVVHLWSVDAA
TGGE---DLAQAERLG---VLLLVKS----KDDVRLWLVTRGSQPVFGQDRLNVAQAPLWGLARVLGQEHMELWGGIIDLDGKTID--------------
--------------------RYIVRVVFTQ---PKFRADASYLITGAFGGLGLQIARYA-ENGARRLILFGREDLPPRNTWRVERIAAVKE-LEALGAGI
HVLGCDVSNREDLFARLAQFEAEGWPAIRGVIHSAGVSVPQTILNMGLDDLSNVLRPKVFGSWNLHQYFRD--DFFVLFSSLAAVVV--PGQANYSAGNA
FLDALAYDRQ-AQGLPGLSINWGPWGEVGMAT-K-----LDGMY--QFSPEKGLEAFGHLLQ--NPNVVS-IKWDV------V-----------------
--------AQNNYP----GGFAPAMIGNESQ----------EVGNDVNFL-EQWKG--ASDD--AQRLMLEEHLQDVVAHVMRL-TLTADQPLNSLGLDS
MLAIELRVSLEKALQV--KLVELLKGPTISELAASLQDQ-----------
>tr|F8F987|F8F987_PAEMK Polyketide synthase PksE OS=Paenibacillus mucilaginosus (strain KNP414) GN=KNP414_04485 PE=4 SV=1
--------------------TNAWLVLADG--LGDALSQLGGLGLTAVMLRPGDG--F----EYRIDPRNPEHYEALLQQ-LADGVRFQGMLHLWNLDAV
VTEE---TLLQSEITG---AVYLIQA----KTAPKLWIVTRGAQAVGDAEGLQIAQAPVWGLGKIIGQEHAEFWGGMVDLDPLSLD--------------
--------------------RHTVRLTLCS---PAMRQDGAYLITGGLGGLGLVTAKWM-QRGARHLILMGRQGLPPRTQWPAQRIAAVRE-IELLGASV
YTAAVDVTDGDSLASWIAGYEAEQRPPIRGVLHTAGVARPKLLLHMTGEEFSDVMRPKAAGAWNLHRQFEA--DFFILYSSIASVVV--TGQSNYSAGNA
FMDALAHYRQ-SLGLPALSINWGPWGDVGLAT-Q-----LDGFY--PMTLEQGLDALGYLMG--YTQSVI-GDWPT------V-----------------
--------ADFNYP----LGQAPLMLGEERD----------EADRQDAFL-TEILA--LEK---GERKQLESYLLDLTASILRI-KLATDQSMSYWGLDS
MMAIELKGRIDSRLQI--SLVELLKGPSISELADLILEL-----------
>tr|A0A0M4SLG8|A0A0M4SLG8_9NOSO PscB OS=Nostoc piscinale CENA21 GN=pscB PE=4 SV=1
--------------------SDCWLVFIDACGIGNQIVLLQNERQNVITVKIGKEFSQISYGEYTINPHSRNDYDTLIKQLHNLGQIPHKITHLWNITSY
NNQIDLENFAATQDISFWSLLFLIQALGEQTKPVAINIVSNNMQQVLDEEYLCPEKATILGLCKVIPQEYAHISCRSIDITIPLVNQRQQLINNLYRELQ
TVASEQVIAYRGNQRWIQCFEPLPIASQTST-NNKFRNRGVYVITGGLGGIGLAIAEHLAKTVQAKLVLIGRSEFPKKVDWLKTKIKKLQL-LEELGAEV
LVLKADVTNLEQMQSAINQVCDR-FGKIHGVIHAAGTP-AGLK---TPELAAKVFQPKLQGTIVLNTVLQNLNDFLVLFSSTTAIT-GGLGQVDYCAANA
FLDGFAHNNFYQHQIPTISINWDWWEWDSWQKSLLAFAPNMKY---GISFAEGIDAFERIL-SQLPQVVSTKNLQTV-----I-----------------
--------AEHQAF----A----------VPFLKNSASPQSQTAHPRP----IL-----ETAYLEPSSAVEQKIAEIWQELLGIDQVGVDDNFFDLGGHS
LIATQIVSQLRQDFQVELSLRHIFEAPTVAELAVVIEDI-----------
>tr|A0A0C2LK67|A0A0C2LK67_9CYAN Uncharacterized protein OS=Tolypothrix campylonemoides VB511288 GN=SD81_21600 PE=4 SV=1
--------------------NHCWLVFIDSCGVGSQIVQLKGKHQNVITIKIGEQFCQIGDWEYTINPQSRDDYDALLKTIRNLGKIPNKITHLWNITPY
NDVTPIEYFEAAQDISFWSLLFLTQALGEQTNSLQISVVSNNMQQLLDEDYLCPEKATILGACKVIPQEYSHISCRSIDITLPQTGQWQQVIDNLLVEIT
TTISEQVIAYRGNQRWVQYFEPLPIENQTVS-NTKLRKGGVYLITGGLGEVGLVIAEHLAKTVQAKLVLIGRSGLPPKAEWQSKKIKKVKL-LEELGAEV
LVLTADVANLEQMQSVIDRVGDR-FGEIHGVIHAAGTP-AGLK---TTELAAKVFQPKLKGTLVLNAVLQDLNDFFVLFSSNTAIT-GGIGQVDYCAVNA
FLDAFAHYNFYQQKIPTVSINWDWWQGNNWADSLMSAIPGLKY---GITFTEGVDAFNRIL-SILPQVVSTQSLQTI-----I-----------------
--------ERVNSF----A----------TFSHKESSSNLSTDKHPRP----IL-----ETVYVEASNAVERKIADIWQELLGIEKVGIDDNFFDLGGHS
LIATQLVSQLRQDFQVELSPRHIFEAPTVAELALVIEDM-----------
>tr|D8G9D1|D8G9D1_9CYAN Polyketide synthase type I OS=[Oscillatoria] sp. PCC 6506 GN=OSCI_4080017 PE=4 SV=1
--------------------KQSWLVFIDGCGIGSQIVRLEKENQDVIVVRVGEKFSQLREWEYTIHPQNKDDYNALIKVLSDLNKIPQIIAHLWNITSN
DRIHALEDLEETQVFSFYSLIFLAQALGEKSDSIEIAVVSNNLQELTDEGELYPEKATLLGPCKVIPQEYSNITCRSIDITLPESGQWEQLIDQLLAELA
VELSYPVIAYRGNRRWAQCFEPLPVKDKTLR-TPKLRQGGVYIITGGLGGIGLAIAEHLAKIAQAKLVLIGRSGLPPKSEWLSTKIEKVQL-LEELGAEV
LVIKADVANLEQMQAMVKQVCVR-FGDIHGVIHAAGVP-AGLK---TTELANSVLEPKMKGTLVLDAVLKDLKDFFVFFSSFTSIY-GGFGQVDYCAANA
FLDAFAHYKFARHQVLTVSINWDWWQWDSWQDALLSFEPQMKY---GITFQEGIEALGHIL-SCLPQVVSTRNLQAV-----I-----------------
--------EQHEDF----ELTT----------LLEKSKDRPQSIHSRP----NL-----KTAYIAPSNDTEYRIAGIYQELLGIDSVGINDSFFDLGGNS
LIGIQLISRLRQDFQIELSIPSLFQSPSVAELAFVIEEI-----------
>tr|A0A0D6YFV4|A0A0D6YFV4_MASLA Uncharacterized protein OS=Mastigocladus laminosus UU774 GN=SP67_20355 PE=4 SV=1
--------------------HSSTLMFIDECNLGCQLVKLQQHNQDVISVKVGSEFTKLSDRLYTLNPQQPDDYDALLNELLTQEKFPEKIVHLWSVTSI
GDTIGLEGLDKAQDIGIYSLLFLTQVLVKQTNEFQITVVSNNMQPVTGEEVLCPEKATILGAVQVIPVEHSNINCRSIDVVLSSSGQEEKLVDQLLTELT
TQSSDSVIAYRGVHRWVRTFEPVKLDKAIKG-KSRLREEGVYLITGGLGGVGLVVAEHLAHTVHAKLILTGRSAFPERDKWISNKIQKLLA-IEALGSEI
QVVSADVANLEKMQEIITQAEKR-YGQINGVIHCAGVV-YAVIFRRSREMTESVMAPKVNGVLVLDQILKNVEDFLILFSSLSSILNTKFGQVGYCAANH
FLDAFAYHKTYKDSIFTVSINWDDWQEVGMSVEALKRFNIAILQKNSLLPSEGIDVFTRILESEFPRVVSTQDLKIL-----L-----------------
--------EQDRVS--------N------ILSLKVAEPTLSKPTYKRP----QL-----SNPYIAPTNETEKIIANVWQNVLGIEQVGIHDNFFELGGDS
LIGVQVISQLNKELNMKIPAVSLYQSPTVSSFAKTLNTE-----------
>tr|K9ZQZ9|K9ZQZ9_ANACC 6-deoxyerythronolide-B synthase, Phenylalanine racemase (ATP-hydrolyzing) OS=Anabaena cylindrica (strain ATCC 27899 / PCC 7122)
--------------------QSSYLVFLDECGLGWQLVRLQQQGHDVITVQVGTEFEKLS--SYSLNPQSSDDYDALVQQLLLKQQLPHTIVHLCNVTLD
P-----EVINEWQTTGFNSLLFLAQALGKHMGEYRLVVISNHLQSVVGDEILSPQKSTLLGPVQVIPQEYPNFNCCSIDIVLPVAGQYEKLLENLLTELR
VASSEQLIAYRGVSRWVQTFEPVRLEKAKDE-TPRLRPGGVYLITGGLGGLGLVLAEYLAKTVQGKLILTGRSAFPQRDEWITATIRKIQE-LETFGAEI
LVVNADVASLAQMKKAIACGQLQ-FGTINGVIHAAGVP-GGVMQIKSIEEAHKILSPKVTGTLVLENIFQDVQDFLVLCSSIAAIKG-IFGQVDYTAANS
FLDAFARHKNSKNSTFTVAINWDAWQQVGMAAKASQQLVST-QTSAGLLPSEGIDAFVRILSSKLSQVVSKNDLHQT-----E-----------------
--------QQLINH----Q----------AEFLATLEINLSQPAHPRP----LL-----SSAYIAPRHEHEQTLINIWQEILGVSRIGINDNFFELGGDS
LLAVRFISQVREKLRIELPINSLFAASTVADLAKYFERE-----------
>tr|A0A0D6YFB2|A0A0D6YFB2_MASLA Polyketide synthase OS=Mastigocladus laminosus UU774 GN=SP67_20345 PE=4 SV=1
--------------------NKQWLVFVDEHGVSLQLVKLKQKGKDVITVKVGKRFTKLSEGIYTINPQNRDDYDALLKDLIALSKTPQNIAHFWTLNTW
DN------YQTSEYLEFNSLLFLAQTLGKHTNRLQIWVVSNQIQEVNGDEKLNPEKATVLSLCKVIPQEYPNITCRSIDVVLPQSDQEEKLIDQLLSEFM
ASSSDLVVAYRNRYRLVQTFEPMRLEPAVEE-KIPLKKQGIYLFTDGLEGIGVALAEYLAQTVQAKLIFVENSILPEKEQYISRKIRKLQA-LEELGAEV
LVVFADVNNYKQMYQNLT--PEK-IGQIHGVIHSSEKI-ENSIQETDKIDLEKLLHFKCYSICVLEEVLQGRQDFCIILSSLSSVLG-GFGLAAYSAANL
FLDVFTRRHNQTDTLPWLTINWDRWQRDETKKQQ-----TFYETELAITQTEGVEVFKRILSLGETQVVSTVDLKAR-----S-----------------
--------DRS-----------FKL--ESLPTNPSPSQWNSSSRYSRP----NL-----SNPYVPPTNQLEKLIAEMWQEILGIEQVGIYDNFFELGGDS
LIATQLVSRWRATFPVDLPLRDFLLQASTVAKQAEMIEE-----------
>tr|A8ZKN3|A8ZKN3_ACAM1 Polyketide synthase type I, putative OS=Acaryochloris marina (strain MBIC 11017) GN=AM1_A0231 PE=4 SV=1
--------------------TTCDLVLIHDGGFVNDLIHLEQQNPNLIFVQPSTAFAQLNDRFYTVNPQSSDDYQTLIQTLVSQHKRLQKIVHLWTLSTS
EKPNDPELVQRCQFSGFYSLLFLAQALAKQSDGIQITVISNYLQSVTGNDPLAPEKSLLLGPIRVIPQEYPTIHCRSIDINLPSPNQAERLTGQLLHDIC
CPITEPIIAYRGHQRYVQAVEKIRLDEPSKE-DSHLRQNGVYLITGGLGHIGLTLARYLAESMQAKLILMGRSTLPEKGEWISRKIRQIQA-LEALGAEV
LVVSADVSNEAELRSAISQAESQ-FGAINGVIHGAGLV-AEAISQLDLVTCEQQFQPKVYGLLVLEKVLNDKPDFCLLLSSLSSVLG-GLGHASYAAANL
FMDALTHYHNQTHSSPWISINWDAWNQDSDTEKM-----AFSLAQFSIEPDEGIRALQQILLHPQSQVVSTADLSAR-----I-----------------
--------DQWIRP----KAIGKK----L--------ALESSHSHERP----TL-----STDYIPPEHKAEKILADIFQQVLGVKPIGIYDSFFDLGGDS
MIGIQLISKIRSHFQIELSIQHLFEAPCIADLAFNIEAL-----------
>tr|H1XP65|H1XP65_9BACT Beta-ketoacyl synthase OS=Caldithrix abyssi DSM 13497 GN=Calab_2570 PE=4 SV=1
--------------------EQNWLILKDDTGLARNFVFILKEPLKLTTVEPGTAFHDQGENKFAMPIDHKESFEKLFEQLKASDRLPQHIVHCWNINAS
SQSS---ILDEAFISGYLSLLYLVQTLQKVTQPLTLTIVTNHLFQVTGYDAYAPLKAIILGLSKVIPQEFPNISCKIIDLKLPHDVSLEPMSQNLIQEVF
AHTDDPVVAFRARDRWTLEFRRIELPQSNPL-HGYLKNEGRYLITGGLGRIGLRLAHYLSRQVKARLALLEVADFPQETSWVSQKIKTLQT-IKENGSEI
LILKADITDAASVQQAVSRAEER-FGGLDGVIHAAGLV-EQPIPELTREDLEAQLGPKLVGALNLRRALHQKTDFVLLQSSVSAILG-GYGFGAYAAANA
GLDALVYLQNQDSNSNWLSVNWDGWNFDETMPSANQ---AQEVARLALTPEEGLAAFERIFANPFGQLVSTGDLHQR-----I-----------------
--------ARWVKG----VQK-------------EETDDKEKAMHDRP----EL-----PYEFVAPQNELQEEIAVVWRKLLGIQNIGINDNFFDLGGNS
LMGTQLISELRAKFQVELPLRALFEDATISGVAKIIEQE-----------
>tr|A0A060Q3I1|A0A060Q3I1_9NOCA Putative polyketide synthase OS=Nocardia brasiliensis PE=4 SV=1
--------------------RGPYLVFTDPETCSAELAHKALGGADVVTVSPGTEFA--TAGGYQLRPGAADDYAQLTTALADRNLLPRTVVHLWSVQGP
Q---SVHGVGAHQRLGFDSLLTLSGHLSRHVDGCRILVVTDHAQSCDAEDELYPGKTTLVGPALTVGQEYPGLAVRTFDVRTPVED-WSELAESVVAELD
---SAAVVARRGRRRLVQRLQPRTL---A----AYVRDGGVYVITGGTGSIGLQMAAHLAAAGSGLFVLLARTPLPDLDDPE--RAVAVRE-LVRAGAQV
LVLPCDIGDRAAASAAIALARKR-FGPIDGVIHAAGLLTD-TIENTTPELVAAHFRAKVDGTLALAHALRDERDFVVLLSSMSAVLG--IGFTAYAAANA
FQDQFVTLRGLPGGSAWRTACWDTWQATRQGEKP-G---VASLDTYSFAPADALAVFDRLIAGGR--AVSA------GQLERL-----------------
--------EAWVP---------AG----DPF---D-----------------SG-----VVPAAATVEDYRRELARLWQAALGVDQVGLHENFFESGGNS
LVGLQLINAINKQFRVVVPTVA-FEAPTVDEMAGYLLTA-----------
>tr|A0A0Q4R907|A0A0Q4R907_9BACL Uncharacterized protein OS=Paenibacillus sp. Leaf72 GN=ASF12_00765 PE=4 SV=1
--------------------KDVWLFLADD--VAEAASILRQQNFEAVIVWPAVEGEY----GSKIHPGTKQHYDSMVKD-LAFGSRLRGIVHAWNLDIP
EPVSGNESFTPHKALS---MLYAVQS----HARVRLWTLTRGAQLVHATKPPAVFQSAAWGLGRSIAQEFRDYWGGICDIDPNAA---------------
--------------------RHVLRLNQAT---LRCREDGAYLITGAFGSLGQNAARLL-KRGARRLILLGRSPLPERHEWVQERIAFVLE-LEAAGVYV
QTLCIDITDQQSLKAFMENYISSGHPPVRGVIHSAGTVQDMLLRQMPAHIFDEAYEPKVKGAWNLHEATRP--EFFVMFSSIAALLP--AGQGNYAAGNA
FMDGLAHYRL-SQGLPAMSINWGPWL-SGMVT-R-----LNGID--CILDGEGERLLEHLLG--IAQVVL-SEWNS------V-----------------
--------RML-------YPDTPLLNKARSEQ---------QIEETINWS-EKLAA--LEPA---GRAAVLAQLTAIIAELLRY-FLETTRSLPELGLDS
MMAIKLRNRITSEFGC--APGDLLSGNTIEMLSDVLVSL-----------
>tr|L7UDX1|L7UDX1_MYXSD Polyketide synthase OS=Myxococcus stipitatus (strain DSM 14675 / JCM 12634 / Mx s8) GN=MYSTI_04970 PE=4 SV=1
--------------------EGSWLLLCDC--VGEALARLRARGERCLLLHAPPA--P----RADVRPDAPADWQRVLDA-VENRGAVRGVVHLWSLDLP
DALA--SATSEALKLG---VLTLTQR------AARVWLVTQGAQAVAE-DRVSVAQAPLWGAGRVLALEHPERWGGMVDVSPAPAE--------------
--------------------RHVARLMRRE---SAWRGDGVYLITGGLGGLGLRTASWL-ARGVRHLVLAGRTELPEPGTWPHAALQALRG-LQAQGTSV
RYVRCDMGEPDQVRALIAECRRGPV-PLVGILHAAGTAEPRAWMETDARVLTSVFQPKALGAWLLHELTQP--HCFVLFSSAASVWG--QGMAAYASANH
FLDALAHHRK-ARGLPATSVNWGRWSEGGMAG-S-----EEGLD--VVPTSAALSMLGRLVD--ITQRVA-ADWAR------F-----------------
--------KPLHEA----RR-RRPLLEGTAAR---------ASVDRPELL-VWLEE--AP-S--GRRHVLQDYVRREAARVLGA-TLEPRRGFFQMGMNS
LMSVELKNQLERNLRH--KLTLAFEHPSVAELSEYLSRE-----------
>tr|Q8RJY3|Q8RJY3_STIAU StiD protein OS=Stigmatella aurantiaca GN=stiD PE=4 SV=1
--------------------QGSVLLLADQ--IARALSKLTEQGVRCILVEPGDA--Y----HFVVRLGEPGDMAQLVKD--AESGGLRAILHLWSLRAA
PLGE--ATLRKAEKLG---TLHLIQA----RLPPRLWLVTRGAQPVSNTVVVSPAQAPLWGLGRTLALEVPSLWGGLVDVDSAASA--------------
--------------------RFVARLVHPA---VTLREDASYLITGGLGDLGLKSAAWM-ERGVRWLVLVGRTGLPERSKWKQQQIAAVQA-LEAKGAHV
RIAAMDVAEEPRLRMLLSDMRQEGWPAVRGVLHAAGVANPKPLADLDAEGLQAIFRSKAEGSWALHRVLEP--DFFVFFSSGSALMS--PLLGGYAAANA
FMDALAHTRR-AQGLPALSINWGFWSEVGMAA-R-----EAGME--SFTPDEGLAVLERLLG--SPQVVM-RDVER------W-----------------
--------IESYPA----AG-QSPIFAASSGP---------EVPSIREAL-A--AL--GP-G--FRRRMLEQHVREQLAHVLKM-QLGMDTPLHDLGTDS
LMAIEIRNRLEKSLEL--VLTLVFTYPTVAALVVFLSST-----------
>tr|A0A0K2M2M5|A0A0K2M2M5_9NOST Polyketide synthase OS=Anabaena sp. wa102 GN=AA650_19325 PE=4 SV=1
--------------------KGDWLILADRS--AETLALLNASGERSHLVYTKKANGK----QHTINWTDPSDWQQLLA-----NRSYQGVVYLWGLDEN
DSCD-----------S---ILHLIQALTSA--SPQLWLVTQGAQLALK-DDIAVWQAPIWGLGKTISLEHPEFSTTCLDLPSGQHSGSEI-IPAMLLEL-
-LAKVFPITEFVAFRYMQQAKHIGKVVLSFQ--CSVRQDGSYLIAGGLGALGLKVAEWLV-QGAKHLVLTGRSSVKQ------AANEAIRK-LEQAGAKI
SVINADISNQEDVKKIL----NE-CPNLRGIVHTAGVLDDGLLKEQTPTRFKKVMASKVQGAWNLHTLTQL--DFFVCFSSVASLIG--AGQSNYAAANT
FLDALAHYRR-SQGLPSLSVNWGPWGEVGMAATL-----AGGWG--IIPTEQGLQALNYLVKNESAQVVL-PNWPK------F-----------------
--------LERLP------E-ITPFLNIT------------SSQERPALV-SQLKA--TL-A--HERRILMEHIRAAIRNVIGLTRIEPRQSLFDLGLDS
LMAVELRNYLEKSVEH--SLTLLFDYPTLEALVNYLLQE-----------
>tr|C4NCC0|C4NCC0_9CYAN Polyketide synthase OS=[Oscillatoria] sp. PCC 6506 GN=anaE PE=4 SV=1
--------------------KGDWLILADRG--AETLALLKGSGQRSHLVYAKTTDGS----QYAINWTDPADWQKLLA-----SKSYQGVVYLWSLDRN
DSCD-----------S---VLHLVQSLTSA--SPRLWLVTQGAQSALK-DAVAFWQTPIWGLGKTISLEHPEFSTTCLDLPSDRHSGAEI--SSMFLEL-
-LSKVFPITEFVAFRYMQQAKHIGKVVLSFQ--ARVRPDSSYLIAGGLGALGLKVAEWLV-QGAKHLVLTGRSSVKK------AANEAIKK-LEQAGAKV
SVINADISDREDVKKIL----SE-CPNLRGIVHTAGVLDDGLLKEQTPTRFKKVMASKVQGAWNLHTLTQL--DFFVCFSSAASLLG--AGQSNYAAANA
FLDGLAHYRR-SQGLPSLSINWGPWGEVGMAATF-----ASGWG--IIPTEQGLQALDYLVKNECDRVIL-PNWPK------F-----------------
--------LERLP------E-ITPFFIVT------------PSQDRPVLL-SQLKA--SL-A--NDRRILMDHVRSAIRNVIGLTRIEPRQSLFDLGLDS
LMAVELRNYLEKSVEH--SLTLLFDYPTLEALVNYLLQE-----------
>tr|A0A097PUH4|A0A097PUH4_9NOST Anatoxin-a synthetase E polyketide synthase OS=Cuspidothrix issatschenkoi RM-6 GN=anaE PE=4 SV=1
--------------------KGNWLILADRG--AETLALLSASGQRPHLVYAKKAHER----KYAIDWTDLSDWQQLLA-----NRSYQGVVYLWGLDEH
DSCD-----------N---ILHLVQALTSA--SPQLWLVTQGSQSALK-DNVAVWQAPIWGLGKTISLEHPEFSTTCLDLPSGNHRGAEI-IPAMLLEL-
-LAKVFPITEFVAFRYMQQAKHIGKVVLSFQ--CSVRSDSSYLIAGGLGALGLKVAESLV-QGAKHLVLTGRSGVKQ------ATNEAIKK-LEQAGTKV
SVINADIANQEDVKKIL----SV-CPNLRGIVHTAGVLDDGLLKEQTPTRFKKVMASKVQGAWNLHTLTQP--DFFVCFSSAASLLG--AGQSNYAAANA
FVDGLAHYRR-SQGLPSLSINWGPWGEVGMAATL-----TGGWG--IIPTEQGLQALDYLIKNECDQVLL-PNWPK------F-----------------
--------LERLP------K-ITPFLNIT------------PSQERPALV-SQLKA--TL-A--HERRILMDHVRSIIRNVIGLTRIEPRQSLFDLGLDS
LMAVELRNYLEKSVEH--SLTLLFDYPTLEALVNYLLEK-----------
>tr|S4Y5I1|S4Y5I1_SORCE Uncharacterized protein OS=Sorangium cellulosum So0157-2 GN=SCE1572_39570 PE=4 SV=1
--------------------RGSWLLLADR--FGQALAQLEARGDRCVLVFAGARYEA----RFAVNPASLDDMQRLVAA-FRARQPWRGILHLFSLDTI
PAEG---DLDRAQALG---LLHLVQA----SELPRIWAATRGVQPVTPLPPTAVAESALWGMMRMVGQEHADRYGGLIDLDPSSP---------------
--------------------RHVPRLVARP---LSFRADASYLITGGLGGLGLLVARWM-QHGARRLVLLGRSALPPRAAWPLQRVAAVRE-LEALGASV
HVAALDIADEAQLTAFLGQHRDEGYPPIRGVIHAAGVSRPHLMAAMTMEEYLETARPKVQGAWLLHRHLEP--DFFVLFSSIAALAF--AGQADYGAANA
FLDGLAQYRR-GLGLPASSINWGAWAEAGMAT-T-----LGGMP--PFSPRRGLEALGHVLQ--IDQAVL-WDPQT------F-----------------
--------ARNNFS----SGGAVPFIGGEAAA---------ASAPPKHPL-QAILE--PADP--AEQERLVDYLQGLVARVLRL-RIDRRSLLNDLGLDS
LLALELKNRIGTDLRA--TVVDLLKGVTVGELARQIRAM-----------
>tr|A0A0F5YFU1|A0A0F5YFU1_9CYAN Polyketide synthase OS=Limnoraphis robusta CS-951 GN=WN50_13390 PE=4 SV=1
--------------------RKCWLIFVDEIGLGEKIVRLIAENQVVAEVRIGEKFIQLTETLFEINPEKFDDYQYLIKILKQNNFVPNEILHFWGTESA
EHFNLEIDFESYQNKSFYSLLALVQAITQQDTLVKLTTVTNNIHDVLGTEAFNPAQVTQLGLCKVISQEYPHITCKNIDVALPENS-FTKGIDQLIAELQ
Q-YTEPVVAYRDRYRWIQTFESVLLPEHSA---TRFIKNGVYLIVGDLEGLGLVYAQYLTQELEAKLILIGRSTLPEKHQWISKCIRKLQA-LETSGAEF
LFFSADLADETKMQSIVTQAYEK-FGQINGVIHAGTMGDS-PLQDLDLEKCHNQFQMKVIGLITLAKIFEGQKDFYLLQSSLSSIVG--VGFGAYTAANL
FMDAFANQQNKTSSTPWISVNWDACQWDESTSQ------KTALIDLAIKPDEVWQISKRILSENISQLVSPRDLHAR-----I-----------------
--------EQSIQQ----KTYENS----E----ILQLADQLNSNHARP----HL-----QTDYSAPRNEIEQIIANAMQDLLGIEKVGIYDNFFELGGHS
LLAIQIISRLREKFQIDIPMRELFESPSVAGIAKIIEEN-----------
>tr|U7QE17|U7QE17_9CYAN Short chain dehydrogenase family protein OS=Lyngbya aestuarii BL J GN=M595_4603 PE=4 SV=1
--------------------RKCWLIFVDEIGLGEKIVRLTAENQVVAEVRIGEKFIQLTETLFEINPEKFDDYQYLIKILKQNNFVPNEILHFWGTESA
DHFNLEIDFESYQNKGFYSLLALVQAITQQDTPVKLTTVTTNIHDVLGTEPLNPAQVTQLGLCKVIPQEYPHITCKNIDVAVGKNS-FAQVIDQLIAELQ
P-STEPVVAYRDRYRWIQTFESVLLPEHYA---TRFIKNGVYLIAGDLEGLGLVYAQYLTQELEAKLILIGRSTLPEKHQWISQCIRKLQA-LETSGAEF
LFFSADLADETKMQSIVTQAYEK-FGQINGVIHAGTMGDS-PIQDLDLEECHHQFQMKVRGLMTLAQIFEGRKDFYLLQSSLSSIVG--VGFGAYTAANL
FMDAFASQQNKTGSTPWISINWDACQFEESSSQ------KTALIDLAITPNEAWQVSQRIISQDISQIVSPRDLHAR-----I-----------------
--------EQSILL----KTSENL----D----TSHSTEHLTSNHARP----HL-----KTSYTEPRNEIEKIVANAMENLLGIEKVGIYDNFFELGGHS
LLAIQIISRLREEFQIDIPMRELFESPTVAGIAKIIEEN-----------
>tr|A0Z9T4|A0Z9T4_NODSP Malonyl CoA-acyl carrier protein transacylase OS=Nodularia spumigena CCY9414 GN=NSP_27060 PE=4 SV=1
--------------------KQRYLVFCHGGGVGEKLVQLEKIGQDVITVKPGERFTQAGD-NYTIALDHPEDYKTLWLQLQTDDQLPDVILHSWTLQEL
TNF------QQQQNLGFYSLLWLIQALSSS-PSVRICVLTQQVHNVLGNETLNVDDATILGLVKVIPQEYPNLTCQHIDVSIPN-----LNLQQIVREIT
TRGLGSAIAYRGKTRWLQEFTPISLPDAEV---LPLISGGVYVIAGDLEGLGLIYAKFLSATVKAKLVFLGRSDLPQPKLWVSHCIQQLQA-LQAQGCEF
LFNSVDLAQIDQVEEAIAHSLTQ-FGTINGVIHAAAMGDA-LIRNLTMDECEKQFSPKIHGLLTLEAALKNQPDFFLLQSSLSAVVG--IGFAAYAGANC
FMDAISHQHSQNSNTPWISINWDAVSLAITT--------PTALVDLAMTPQEVWQVTQRILAQPAAQIVSPIDLESR-----P-----------------
--------QSQIPE----NS-------------------ISASNHARP----QI-----STTYVSPSNEIEARVTQVMENLLGISPIGIHDNFFELGGHS
LLAIQAVSQLRSEFQVELPMRQLFESPTIAGIAKIIREN-----------
>tr|Q8YTS8|Q8YTS8_NOSS1 Polyketide synthase type I OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=all2635 PE=4 SV=1
--------------------KQRYLVFCHAGNAGERLVHLQETGQEVVTVKPGEGFTQEGD-NYAIAPHNPEDYKTLWLQLQTDDKLPDVIIHSWTLQER
TNF------QQQQNLGFYSLLWLTQALSSS---LSIYVLTQQVQNVLGNENLNPDDATILGLVKVIPQEYPNLTCQHIDVSISD-----INFQQLVREIN
IKGLRMSVAYRGKTRWIQEFQPISLPE--P---LPLITGGVYVIAGDLEGLGLIYAKFLAATVNAKLVFLGRSDLPQPKEWVSHCIQQLQG-LQAQGCEF
LFTTVDLAEISQVEDAIAQALTR-FGKINGVIHAGVMGDA-LIRNLTIPECEKQFHTKIHGLLALETALKNQPDFFLLQSSLSAVVG--IGFAAYAGANC
FMDAIAHQRTQNSNTHWISINWDAVSLAITT--------STTLIDLAMTSQEVWQVTERILAQPAAQIVSPVDLASR-----Q-----------------
--------QSQPLE----Q---------------------STTNHARP----QI-----TATYLPPSNEIEARVTQVMESLLGIAPIGVNDNFFELGGHS
LLAIQAVSQLREEFQVELPMRQLFESPTIGGIAKIIIEN-----------
>tr|A0A0F7BLM5|A0A0F7BLM5_MYXFU Polyketide synthase OS=Myxococcus fulvus 124B02 GN=MFUL124B02_19445 PE=4 SV=1
--------------------PRVWLVFEDEASPTDALLAAPGEERRVLRVRPGTAFRRTGDSEFTVAPGSLSDFRALLGALRDAGLLPDAVLHLWSLTPG
LP----TSFAQAQASGYHSLVALARALIEHEKPCSIWVVTNNVHEVTGDEALSADKATVLGPCQVVSQEQPFLRLRHVDVVTDADFLAPASLQSLRAELR
STALDTMVALRGPHRWVRTLEPLPLPDATGA-QVLSRPGGVYLLVHGLSGVGAMNARLASISPGAKLVCLEPSDLPSREHWLSQRIRRARQ-LETLGAEV
VVLSVDVTRQESLREAVDAALAR-FGALHGVVYGAWLP-EQLVSETGPDESAWHFDARVRGLALLDQVLGERPDFRVVASSISSVLG-GMATVAHTAASA
WQDTFAQA-ATRAGRRWVSLDWDVVRVEDYGAHP-----GAALDRLAIAPEQGAEALARVLSQTGAWWVSTHDPVAR-----Q-----------------
--------ARPRAV----E--------------AVDSTPAARPQHPRPS---NL-----RSAYVAPTTEMERTLTELWQQTLGVAPIGIQDNFFELGGDS
LIAVQLSDRLKRRLDISVPASSLYEGVTVKALAALLQPP-----------
>tr|L7UBF3|L7UBF3_MYXSD Polyketide synthase type I OS=Myxococcus stipitatus (strain DSM 14675 / JCM 12634 / Mx s8) GN=MYSTI_03596 PE=4 SV=1
--------------------PRVWLVFEDAASTADSLLPEPGAEQGVVRVKPGTGFQRHNDTDFTMAPGSQADLRELVTTLRESGRLPDAVLHLWSLTAE
PS----ASFAQTQASGYHTLVALSRVLVELERPCTVFVVSNHVHDVTGDEVLSADKATVLGPCRVIPQEHPHLRFHHVDVVTEAGVLSPASLQALRTELR
AAPREAVVALRGAHRWVPVLESLPLPEAPAP-HPTARAGGVYLLVHGLGGVGAMNARLAKLSPGAKLVCLEPVGFPARDAWQAQRIRRARE-LEAMGAEV
HVVSVDLTNEEALRAAVDSTVTR-WGALHGVVHAAWLP-QKLVSETGPDETAWHFDPRVRGLALLDTVLGDRPDFRVVASSISAVLG-GISTVAHTAASA
WQDAFAQA-ATRAGRRWTSVGWDVVRVEDYGAHL-----GAAIDRLAVAPEQGAEVLDRMLAHAGPWLISTHDVKAR-----Q-----------------
--------APPQPL----P--------------AQ--EVVARPLHPRPS---NL-----RSAYVAPTTELERLLADLWQQMLGVTPIGIQDNFFELGGDS
LVAVQLTDQLKRRLNLSVPASSLYEGVTVKALAALIQPP-----------
>tr|A9AV06|A9AV06_HERA2 Beta-ketoacyl synthase OS=Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785) GN=Haur_3962 PE=4 SV=1
--------------------QHTWLLLVDDSGLGLVLARLKQHGQTVVTIAPGAAFAAIDPASYTVRPAEREDYISVIKKLAREGIEPSRVLHLWLASPA
ESAGSPAEVDGILERGFYSLLALTQALGNQ-ERCEVNVVTTGVHAVVGQEAVNATKSTVIGPCKIIPQEHPNLTARSIDVIWAPDRGCEELVDRLVVELA
STPTGVVIALRGQHRWVQAYEQIHLPEFSHP-HARLRDQGVYVITGGLGGIGLALAEYLVASVRAKVVLIGRTALPSRERWTGHRVHCIRQ-LEASGAEV
LVLQADVADAGQIAAAIDQAVAR-FGAINGVFHAAGVP-VGLMQLKTAEAAASVLAPKVQGTLAIAQAVRSLPDFLVLFSSVAAAAGGGQGQADYCAANI
FLDSYAQLH-HRDNGVTISIGWGEWHWDAWSEGLQGFTEEVSRRTFGIDFADGMEALRRILAYDLPQIVSPRDLTFL-----V-----------------
--------EASQRS----FAA------------FLKMEDREQSRYPRP----AL-----AVAYAAPRNDLETRIATIWSDVLGIDPIGIDDNFFDLGGNS
LLGLDLFGRMRKALKLNFPAYVLYESPTVELQAAHITNL-----------
>tr|A0A0C1RDM4|A0A0C1RDM4_9CYAN Uncharacterized protein OS=Tolypothrix bouteillei VB521301 GN=DA73_0203475 PE=4 SV=1
--------------------QSNTLVFIDECGLGSQLVKLELEGQNVITVKVGSEFIKLRDDVYTLNPREENNYNALLNELRTQGKTPQTIVHLWNVTSE
GEAEGPESIDKSQDLGFYSLLFLAQALGQQSEKLRIAVVSNNMQEVTGVEALCPEKATLLGPVKVIAQEYPNISCCSIDIASAPQRQEEKLIDQLLHELQ
TQFSDRVIAYRGSHRWVQTFEPVQLDKPNEA-TPGFRKGGVYLITGGLGGIGLVLAEYLATTAQAKLILIGRSALPPTEEWVSLKIRKVRK-LEELGAEV
LAIAADVSNLQQMQEAIAKAKAR-FGQIHGVLHAAGVP-GGAIIGKTRDSVEKILAPKVKGTLVLDSIFKDTPDFFVLTSSITSI-IGGFGQVDYTSANA
FLDAFTHYKNSQGDNFTVCTNWDTWQEVGMAVNVSL---PDEMLKLAILPAEGVDAFSRILGTQLSQVICPRDLHLR-----E-----------------
--------AWENT---------P-------KFLEPSETISSRPSHPRP----EL-----SNAYVAPRNELEQTIANIWQQLLGIEQVGVYDNFFELGGHS
LLATQLISRMRETFQVELPLNSLFEESSVAGLAER-IDK-----------
>tr|A0A0K1JV17|A0A0K1JV17_9BURK Uncharacterized protein OS=Massilia sp. NR 4-1 GN=ACZ75_04085 PE=4 SV=1
--------------------ADGWAIVGGADQQVAALSTLADLGQAAECASSAAGLGALA-------PGI------------------RTVIALDGIADH
M----------PSTELYYRALALLHGLSRR--PTTVLFVTRWTFAVPREREIEPERAAVIGLAIAAAQEYPQLSCRLIDLDAAALSFGGAHAAALLAEA-
LPQAAPWIAYRGAQRWVLTFEPAPLAPVQP---LAPAFEGCYLITGGLGKIGLLIAEFLARRGAATVVLTGRRAMPPRTQWSDPRLGRLRM-IEAMGTKV
VLCSGDGGVAADVARLVAEARAQ-GGKIHGVFHAAGLTA-AGFADIGRDVSEAHFAAKPRAARLLAEALRDDPGFICLMSSISAVLG-GIGFGPYAAANA
MLDALAAQ----GATRWLSVNWDGWSFDTQ---------GAASSEALICADDGIDVLERVLAAPIRQLVSVAPLGPR-----L-----------------
--------QRWLQP----PAAVA-----A-----P--AAAPSASHERP----EM-----SAGFVAPTPGRQTLVADLWRDLMGISPIGADDNFFELGGHS
LLAIQVVSRLREALQRDLPVRILFDHPTVAALAAALDAL-----------
>tr|H8MFK9|H8MFK9_CORCM Malonyl CoA-acyl carrier protein transacylase OS=Corallococcus coralloides (strain ATCC 25202 / DSM 2259 / NBRC 100086 / M2) GN
--------------------GQRWLVLEADTPVASRVSRLRQAGADVVSLVAGQGASDPVTKRFAVDPSSPDALGEHLERLRGEDWSPAHVAYLWPLVKD
S-----RDLESGLATSFHGLLALAKAVGPG--PVTLDVVTTGAQDVTGEEPLLPWQAAAVGASRVLPQEYPGLTVRAVDVTWPAPE-SGPWMERLVTELA
A-GKDPVVALRGPYRHVEAFETIDVPAPTE--QG-LKDGGVYVIVGGLGRVGLALAEQLTQAVKPKLVLLSRRTLPAPGEWTSKAIDRMRA-LERSGAQV
LALRADAGVPGQLDKALQVAEAK-FGRIDGVFYAAGDGG-ASVAEATPEATTPLLSGRFGGLTRLAEALASRQDFVVVQSSLTVVLG-GMAVSAVAAAHA
GMDAVAARR--LGGTRWYTVDWDVWGVGE----------GF-RPDAVIPPTEGFRLLRALLTQPGGRFASLGSLEAR-----R-----------------
--------QVARDG----AST-----------SRA--GGSGSGKHPRP----PL-----ANAFVAPRDETEEKVAALWQDLLGVESVGITDNFFELGGHS
LLGVQLLSRIREAFQVELSMRALFESPTVEVMTVAIVEA-----------
>tr|H8N207|H8N207_CORCM Malonyl CoA-acyl carrier protein transacylase OS=Corallococcus coralloides (strain ATCC 25202 / DSM 2259 / NBRC 100086 / M2) GN
--------------------NGGWLLFVDGPGT--AVARLRRSGCSVVEVVPGSDFLPLAADRFAMDGTRPEHHAWLLEALGDARPERVAFLDGWALAGH
APGS--AHVEAAIARSFYPPLYLARAMEAR--VTSLTVVTAGAHDVTGEEPLDPAQALALGPCRVLPQEGPGWRCRAVDVTVPPKESARMWLDTLVAELE
SDPRDAVVALRGRHRWVEDFAPVSLPDV-S--TGLLREGGVYLITGGLGRMGLALASRLATEVRARLVLVGRTGLPPREAWTSRKLRVLED-LERQGAEV
LVVSADVTSDEDCQRMVALARER-FGALHGVIHAAGVVG-PLVSEVVPSRCGLLFEAKVHGLLALTRALKAEPDFVMLQSSLSTVLG-GLGFAAYASANH
FLDAFAAER--HGETPWLSVDWDGWTE------------E--AGRLGLTLEEGARAFQRILGLGGGRLVSTGELSAR-----R-----------------
--------ARGTVP----SEAAAA----V-A-GAP--GSRPASAHARP----AL-----GTPYVAPEDAIQQQIAELWQELLGVDRVGIHDNFFELGGHS
LLGMQVVSRLRELFSVEVSIRGLFETPTVLGVVNAILEA-----------
>tr|D8PF63|D8PF63_9BACT Putative Polyketide synthase OS=Nitrospira defluvii GN=NIDE2152 PE=4 SV=1
--------------------HDHWLVFVGDRETESVLRQLESRVASVTAVFPGAGFECHADGSYRVRPDSREDHASLLEELTARGQVPHCLLHAWGLEST
GTDTADTRMRTAQERGFLHLVILAQTFGGR---CSILVLARGLHDVTGDELLRPEWTTMLGACLVIPQEYAVLSCRLLDLDRRAFQ-VNVWGERLVTEAG
LSRGAPVVAYRGQHRWVRTFEPLCLDAKGG--DLPFRQGGVCLITGGLGGVGLHVAEHLIRTVRARLVLVGRSHPT------AEQREFVAA-LERLGNEV
LVCRADVADRAQMQRVIDEAHQR-FGGIHAVVHSAGVAG-G---LKTPNAVWEEFRAKVQGAAVIDALFRDEPELLLFCSSLTAVAG-GVGQSAYCAANA
FLDALAHAR--REARRVISVNFDRWRHIGMARQAEA---TLDSDVDGMDAVEGLEVLRRILAGPLAQVQSIRDLPAV-----M-----------------
--------ASVSHL----GLLDRG---GL-S-QKAK-----------------S-----TDELIVEKEGLEAQLAALWRQVLGLEHVGLEGDFFQLGGES
LSALQILNRIQELHHVELSLREFLSAPTIHGLAGQIRTA-----------
>tr|I4MQ87|I4MQ87_9BURK 6-deoxyerythronolide-B synthase OS=Hydrogenophaga sp. PBC GN=Q5W_1764 PE=4 SV=1
--------------------PGTWLIAGGADALAEALARVREAGASALRIKEAGEAESAV----------AQA--------RAGGQPVVGAFALWGLGAG
AATP----------KQRDWLHHAPVALAAASEPVRVIVATAGAHSVLGEPVAQSAAALAVGPVLALPLEMPGLRGRQIDLEAGV---DDLAAQHLCDEAV
ARDEEDMVARRQGQRWLRRHEHTALPAANA--DLPLSEGAVVLMTGGLGGMGLAIAQRLAERRRARLLLTARTALPPRAEWHSLTITALRA-IEAAGGEV
ELAQADAADASAMAAAVQAARAR-WGRIDAVIHAAGVAGGS---LKTPESIEAVLAPKLDGLRVLRELLADTPELVVLMSSINAVLG-APGVADYASANA
VLDAFAESV-PPAWRRVVAFDWGAWREVGMAAKLEV---PAAYLAKAIGTQDGLDAFERVLAS-LRRVVVPYDLPKA-----L-----------------
--------SLTRAA----ALKPPA---EA-P-RTE--SAPREATPAKD----AA-----PAGARLPQGEVQTRLAAIWVELLGVDSVAAHDDFFHLGGHS
LLATRVLARIRESMGVQLALRDMFDASTLQALAQRVQEG-----------
>tr|E3FPD0|E3FPD0_STIAD Polyketide synthase subunit OS=Stigmatella aurantiaca (strain DW4/3-1) GN=STAUR_4158 PE=4 SV=1
--------------------GSGWLVFLDPTGIGQRLVKLEAGGAEVTCVSLGTEFSRKGEKRFELAPGQQAQFRMLGEELQRLGRLPGHVVHLWGLTPE
TAGQEETVVRSQQELGFYSVLFLSQALAEH--PLQLDVIAHGTQDVTGEEPLSPGKAMVLGLCTVIPQEHPAMRCRSIDVEPPEAGRLS---ARLFQEVL
SEVHGHGVAYRGHRRWVEFFEPVRLGAPGE--DGLLRERGVYLITGGLGRIGLVLAEHLGAAVQARLVLVGRSFFPERGAWTSQKIRRLLA-LEQKGAEV
LVARADISQPAEVEALLAKVQAR-FGGLNGVVHGAATTG-EPIREADKDACENQFRSKIHGLRVLRDALRGKVDFVLLQSSLASILG-GFGFCAYSAANR
FLDALAALR--GGSTRWISVNWDGWEFGG----------VGQSGALPMSASEGVEAFQRILSGDASNWVSAEALESR-----L-----------------
--------AVWIE-----QKGSAK----A-A-QDK--PVEVASLHQRP----DL-----PTEYVAPRDDLEAEIAGIWAELLGVQQVGIHDSFFLLGGHS
LLGMQLLSRIREQLKGDIPLRSLFETPTVAGLALLVVQQ-----------
>tr|I1D2G6|I1D2G6_9PSEU Polyketide synthase family protein OS=Saccharomonospora glauca K62 GN=SacglDRAFT_02241 PE=4 SV=1
--------------------ETWLVVGATGSV-VERLV---HSAARMIRVSWDASFA--GGDRFTVSPHEVSDWTKVLRTVSESGSVPARVVFGAD----
----------ERDFTALYGLMLLMRAWRDCVDDVEVGVVSVSGLPVAGESEVFPERGMLAALCRVIDQEMPQARCRFVDITPATSP---RLLTRLVTELR
---TDDCVAYRGDTRWVRGFVPARL--DR----TRLRDGGCYLISGGLGRIGAVIGDLLAT--RKAIGVIRRSVVPDRADWPVAEITTIRR-LEAAGATV
AAASADVSDPERFAAAVARLENE-LGPFDGVFHVAGVVTD-PLAEATPERARPHLAAKADGVRVLADVFAGREDFVLLCSSIASVLG--IGFPAYAAANL
YTELFAAARSAEGGTPWTALAWEGWTVDDRAAPE-----TAYLIDE----NDAREVLERVLSGDA-QLNS-------TGDARF-----------------
--------DQWSG---------TR----E-----T-SAPRSSAAHARP----EL-----QTTYVAPRNDTERRLAEIWQDLLGIDRVGVHDNFFELGGHS
LLGTRVIARVLRELRVQVPLHT-LTEPTVAGLASAVAEL-----------
>tr|A0A0M9E7J1|A0A0M9E7J1_9DELT Polyketide synthase subunit OS=Candidatus Magnetomorum sp. HK-1 GN=MHK_004304 PE=4 SV=1
-----------------------WIIFLDHEGIGKQII-LSDKNVNIITVEKGKKYQ--GSNAYTLNASNHNEYEMLIKSLDGITI--HQIVHLFQVSSD
-----TNDYSQLMNNGFYSLLFLGQALGKHSQ-IIVTTISNNMKDITGNDKIYPEKSAILGPLLVLQQEYQNINCRNIDIVLPGKEQEKRLIEQITSELI
---GNLQIAFRGNYCWYQTYEKITLEKPET---QLYRKNGVYLITGGLGSAGFEISKYLAKKVNAKLILVCRTKIPSKENWISERIRKIQT-IEMAGAEV
FIGAANVKDLSEMKAIIEEAESQ-LGGINGVIHAAGLVDA-YIADTDVSECKKHFDAKIHGTKILDQLFQEHDDFCVLFSSLASILG--LGFAAYSAANI
FLDHFVEAKNQNIRKNWKTINWGDLNFDKPEESTQNFDTVINLEALIINPDEMINTLERILLSNVNEWVTPGSLYAR-----I-----------------
--------AQWVKY----DSMDHED-TST---S--------NEFHSRP----DL-----FNPYTEPTNETEKKLSNIWENLLGISPIGINDNFFELGGNS
LLLTQLASKVRNTFQLDIPLHH-FEKTHIKPLAKQIDTI-----------
>tr|A0A080MEG8|A0A080MEG8_9PROT Beta-ketoacyl-acyl-carrier-protein synthase I OS=Candidatus Accumulibacter sp. SK-02 GN=ppsE PE=4 SV=1
--------------------RGPWLLFTTGEGFSEHLAQLQADGQAVIRVLPGTQAGWSGERRYTLDPARRADYDSLLAALSSAGQLPKTVLHAWNLAPA
AGAPDRESFARAQDLGFNSLLYLAQALGERTEALRIGVLGTGIQALTPGEQPIPERAGVLAACIVIAQEYASVDSRCYDLLPPAVGAEQALGRQILREIG
SDAPDAIVAYRDGVRWVQHYQPRHLEPVSGP-PARLRPQGVYLISGGLGAIGYALAEELVRSVQARLILTGRSALPPAAEWDNQRIARVRA-LERLGAEV
LVVSADVADDDAMTRALAQARSR-FGHIDGVIHGAGIV-EQAVQDTRPEHCAEHFRPKVDGLLVLHRLLRDDPDFYILLSSISAVLG-GLGYAAYAAANA
YLDAYAAHASRQSGPAWLSIGWDAWLSAASADRHGMG--AV-VNTLAMSTAEGVDAFRRILAADGAQVVSTSDLPTR-----V-----------------
--------EQWVKR----KPRAA-----A-----------TPMADATP--------------SITYATAMQTAIARIWENVLGVSQIAAQDNFFDLGGDS
LLLMDVIARLKAGYGIVLNPREIMFQ-TLAQLAAQCEAR-----------
>tr|W4LZV7|W4LZV7_9DELT Uncharacterized protein OS=Candidatus Entotheonella sp. TSY1 GN=ETSY1_00050 PE=4 SV=1
--------------------TLCWLVFVDDCGLGPQLAQLQQGGQTVITVTAGEAFHQQDTLTYTLNPSREADYQDLFNALRTAETLPDRIVHLWGVTPA
SPGP--ATTDTIQNHGFYSLLSIARGLGEHTEPLHISVISNQLQAITGDESLLAEKATLLGPCRVIPQEYPHITCRSVDIVLPQQTAAHGLVEQLMTELI
SETPEVIVAYRGQHRWVQIFESVRFNSERA---TALRPGGVYLITAGLSDTGLTLAHHLAQTVQAKLILLDATPFPDPSDWTSHKIDQLRT-MADLGAEL
LVMQADVTELAEMQSALKQAEQR-FGPLHGVFHLTSTR-SGLIQLKTAEQAQQVLAPSVIGTRVLNALLRDQRDFLALFGSVVSVTG-GLGQVDECAANA
FLDAYTYSHDLPQPCHVVTIDWPGWQWDDYFEQSMASFPQVQRERYGITPEELGQATAQLLASDLSHVVSTQNLDLV-----I-----------------
--------ELQTGQ----TTTNL-----V--------AQLDTAGSAQP----RS-----EGTYVAPANEIEAKIAKVWAEEFGIEQVGRDDNFFDLGGHS
LMAIQVISRTREVLEIDLPLSSLYSHPTVAALAELHMTT-----------
>tr|S4Y1D7|S4Y1D7_SORCE Uncharacterized protein OS=Sorangium cellulosum So0157-2 GN=SCE1572_31230 PE=4 SV=1
--------------------RSTWLVFIGDEGLGAALVGLARRGHEVVAVVAGERFEQTGPQRYTIDPAAKGDVASLFARLEVEGRMPDRIVHAFCTSPA
DGARGGAALEIERRLGFDSLLLLAQVIAAQPKPLMLGVITTRAHSVIGTEVIEPLRALVLGPCRVIPQEMPHVSCRNIDVDLPGEG-RAEIAARLIADLE
RESPDAVVAYRGGRRWVESIELTDVGRRSA---PRLRQRGAYLITGGLGGIGLVAAELLAREAHARLILVGRTGLPARQGWTSRKIVRIRA-LEEAGAEV
TIAAADVSDFDAMRSVIEEARTR-FGRIDGVIHSAGIA-GGVIQLRMPTAAWRVMAPKVGGTLVLDALLRDERDFLLICSSLASLVG-GATQIDYCAANA
FLDAYAQSREGEEGCRVISVQWDTWSDVGMAVDFELP--ADETLKRGISSSEGAEVLGRILSAGSGPLICTSDLPAY-----K-----------------
--------QSVTT-----------------R-RSQHEAPAARPLHSRP----TT-----TGAYVAPETETERRIAVIWQDLLGLEQVGANDDFLQLGGHS
LLATQVLSRVLLTLKVGISLPQFFDVPTVAGLSRLVDAA-----------
>tr|A0A0A7AD68|A0A0A7AD68_9CYAN HapE OS=Hapalosiphon welwitschii UTEX B 1830 PE=4 SV=1
--------------------KLCWLVFIDACGLGSQLVQLEQNSQDVTTVMLGEQFTRHGESVYTINPRKRDDYEALLKELHSLNKAPKTIVHLWSITPN
ADTSEIEFFEKSQYLGFYSLLFLAQALGEQTDPLQIVVVSNNMQEVTGVEALCPEKATVLGPCRVIPQEYPHITCKNIDIVISESEDEGGLLGCILSELA
APPSNLVVAYRETHRWVQTFEPLKLEESVKE-TLQLRSHGVYLITGGLGGIGLVLAEYLAKTVQARLVLIGRSAFPRKDQWVSRKIRKLQV-IENLGAEV
LIKSADVANLEQMLSAITQAYEC-FGEIHGVIHAAGIV-TETIQETSQVECSEQFQAKVRGLFVLKKVLQGTADFCLLTSSLSSVLG-GLGFVAYSAANL
FMDAFAYK-CKQTGTPWISTNWDGWKLQEEKKQN-----IATLAKLVITPTEGVEVFQRLLSISPVQVVSTGDLQAR-----V-----------------
--------DQWIK---------RE----SLGD-TKSPKVDSSSLHLRP----NL-----HNAYVAPKDDVEQTLANIWQEFLGIKQVGVHDEFFELGGHS
LLAVQLMARIEQQFKKNLPLATLFQNSTIERLATILRQP-----------
>tr|S0FVE6|S0FVE6_9FIRM Beta-ketoacyl synthase OS=[Clostridium] termitidis CT1112 GN=CTER_1459 PE=4 SV=1
--------------------GGTWLIFEDETGLSENIVTLKEEGVQLVTVSKGHQYCKMNQSAYTINPKTKEHYVSLVKDVFK-GNKPGSILHLWNVTEE
ELGCTLEFSEECLSHGFHSLLCLAQALGETDHNIKMAVVSNNMQVISDEKVCYPAKAVITGPCKVIPMEYSNIFCQSIDLVLKGIGEKSRFAKAILAEIS
AEEPQTTIALRGNHRWLPTIECTTLESINER--SWVKEGGTYLITGGLGGIGLAAALRMAREAKVNLILTRRSAFPEKDQWAGDIIKQVKA-LEALGSEV
MAIQADTSDLEQMSEVIRQAKSR-FGSIHGVIHAAGIS-NGLIQEKQAEAADKVFAPKVAGTLIIDELFKDEDDFMALFSSSSSILG-EAGFIDYCGANA
VLDAYAHYRSQMSNTFTVSVNWDEWDEVGMAVKTGSR--S---KRQKITVHEGLTLLERIIASKLAQVVVPDDFMGR-----L-----------------
--------QEIEEF----RMSSV---------RGNSGAKVTNQSNNRP----NL-----DVPYTAPQNELEEVIAGIWQEQLGVYPVGIHDDFFELGGHS
LLATSLITILRKKFHRNVNLQSFFEQSTVAQLAKILGDS-----------
>tr|G3J047|G3J047_9GAMM 6-deoxyerythronolide-B synthase OS=Methylobacter tundripaludum SV96 GN=Mettu_3715 PE=4 SV=1
--------------------APEWLVFADELGLADALAEQTQNGRQVFKVNPGSGFAQPHERAYTVNPVQPADFDALLEALQQQNALPQQIVYLWGFSQS
NPAA-------DLNRHCDSLLALIQALGRLRLPIELTVVGNNMQAIGADHPIDPAKAALLGLLRTLPWEYPNLSCRAIDIPLPATEQLHSLASRLARELS
IPAQDPLVILRTGYRWLPSLEAVRPDSPRET-ACLLRNGGVYVITGGLDGIGFLFARQVAAMVQAKLVLTTAGSLES-----AANAQQLQE-LEALGSEV
LPIQLVDYDTPSLNAVLNQAEHR-FGRIDGIIHAADMS-PRLMQDIHKTEQDAYWQAQQLTLNALKQSLEHRNEFCLLMSSLAAEVG-GIGQAAHAAACV
YTEAFARQHNQTGAYPWIVVHWDVWQEEGDRTDINSA--L---AEIA-TPEEGGNAFQRLMALGSTCIIATSDPRFR-----R-----------------
--------KAFSRL----QE------------DQPGATPAAGRRHERP----DL-----SNPYEPPRNEDEAAMAELWQEFLGIDPIGIHDNFFDLGGHS
LLATQLVTRLQQSFKVGVELVLFFTAPTIAELSEALLQK-----------
>tr|B2IXJ8|B2IXJ8_NOSP7 Beta-ketoacyl synthase OS=Nostoc punctiforme (strain ATCC 29133 / PCC 73102) GN=Npun_R3024 PE=4 SV=1
--------------------PGCTLVFSDDCGLGLGIVQLELEGETVITLKVGSEFHQISERLYSLNPKNHQDYDTLLQELHRQGLQPQKIIHLWSVTEN
YTPEEIAEFDKAQETGFYSLLFLAQTLAKHIDELQITVVSNNVQQVTGVDIVCPAKATILGPVKVIPQEYPNITCRNIDIIIPKSS--DKLVEQIVAELT
CDNLDKVIAYRGYHRLVQTFEPVQWDESVVG-TPRLREKGVYLITGGLGKISLLLAEHLAKTVQGNLILIGRSPFPAKDSWISQKIQKLIE-IESFGGKV
LIINADVSNQQQMQAAIDLAKEK-YGRVNGVIHAVAIA--DAIEQTSYQECLQQFQPKIHGLLVLEKIFQNQKDFCLLLSSLSSILG-GLGFVAYSAANN
FLDIFAHKYNPNNSIPWISINWDAWQFDSEPKIT-----GN-LAELALNPQEGIKIFQYIFSQPVNQWVSTGNLQAR-----I-----------------
--------DQWIQL----KILGN-----R-----KDLSASSITHHARP----NL-----RNAYIAPSNEIEKCLVNIWQDLLGIEPIGIEDNFFELGGNS
LTAIQIISRLREIYLIDLPVNDFFETPKIISLTETIFQA-----------
>tr|A0A0C2LQD8|A0A0C2LQD8_9CYAN Uncharacterized protein OS=Scytonema tolypothrichoides VB-61278 GN=SD80_00755 PE=4 SV=1
--------------------QSNTLVFIDECGLGSQLVKLELEGHNVITVKVGSEFTKLSECVYTLNPGQGNDYNTLLNELRTLGKTPQTIVHLWNVTPN
SEAEGLESIDKAQDLGFNTLLFIAQALGKQNDKLHIAVVSNNMQELTGVEVLCPEKATLLGPVKVIAQEYPNISCCSIDVVIPPKGHEEELTLQLLAELT
TQSSDKVIAYRGLHRWVQTFEPVQLDKSNEA-TPQLRKEGVYLITGGLGGIGLVLAEYLAKTAQAKLILIGRSALPVKEEWVSLKIRKVEE-LEQLGAEV
LAIAADVSNQQQMQEAIAKAKDR-FGQINGVIHAAGVP-GGVIQAKTTDRVEKILAPKVKGTLVLDSIFKDTPDFFVLTSSITAI-IAGVGQVDYASANA
FLDAFTHYKNSKRGTFTVCTNWDTWQEVGMAVNAAL---PAEMLKGAIAPDEGVDAFSRILESKLSQVICPRDLQIR-----E-----------------
--------DWENT---------P-------KLSEPLETISSRPTHPRP----EL-----SNAYVAPGNELEQTIANIWQQLLGIEQVGIHDNFFELGGHS
LLATQLISRMRETFQVELPLNSLFEESSVAGLAER-IEK-----------
>tr|K9X6G3|K9X6G3_9NOST Beta-ketoacyl synthase family protein,acyltransferase family protein,phosphopantetheine-containing protein OS=Cylindrospermum s
-----------------------WLVFVDACGLGKELV-LEQQKHDLITVFVGKQFA--SDNAYIINPQRQDDYEALIQQLRQLDRIPQAIAHFWNVTSY
DQS-ADRDFENSQYLGFYSLLFLTQALDKQTYPLQIITVTNNLHEVTGEESLNPEKATLLGPCKVIGQEYPNIFCRSVDVVIPKST-NEKLIDYLIEEFT
---DDLIVAYRGHHRWVQTWEPVQLGAVIE---TRFRNRGVYLITGGLGNIGFTFAKYLAKAFKAKLILLGRSDLPIKENFVSRQIQKVKA-LEELGAEV
LVISADVANFEQMQVAIAQADEY-FGKINGVIHAAGIVGDNLIQEIGKAECEMHFQSKVHGLFVLQKLLHSREDFCLLLSSISSILG--LGFVAYSAANL
YMDAFTYQQNRTKTVPWISLNWEGSPVDKEEQQNTNN--QSTLAELFITTTESVEVFKRVFS-ILSQIISLGELQAR-----I-----------------
--------NQWLKL----ESIRDVE-PSK---QDTERQKDSPQLRPRA----NL-----QTAYVPPRTPVEFVVANLWQQLLNIERVGIYDNYFELGGHS
LVAVRLMAQIQRKFGQNIPLAA-FQAPTVEKLASVLQET-----------
>tr|Q6E7J4|Q6E7J4_9CYAN JamP OS=Lyngbya majuscula PE=4 SV=1
--------------------TTTHLVFVDEFGFGDKIVKIERDGQNVITVKVGTEFKKLSDRLYNLNPEQENDYHALCQELRERNENPKTILHLWSVAPN
SKDKEIEWVEKSQNLGFYSLLFLTKALGRQSGELLLGVVTNNMQKIGSEALLNPEQATVTGPILTIGQEYPNIICRSIDVVVPESGEEEILIEQIGSELA
IEQSEKMVAYRMGDRWVQTFEPVRLEEGDKT-NPRLKPGGVYLITGGLGGIGLILAEHLAKTVQAKLILIGRSKIPPAEEWISQKIHKIRK-LEALGSEV
LNICADVANLQQMQDAISKALKR-FGQLNGVIHAAGIV-DKTIAKAAKTECEQQFKPKVKGTLVLAKTLEKLEDFCILMSSLSSVLG-GLGFVAYSSANS
FMDAFVHQHNQTSVVPWIGVNWDGWQVIEAKKTS-----KSSLVELAILPEEGINVFQRILSTNLHRIVSTANLQDR-----I-----------------
--------NQWVKL----KSLQQ-----SDKKKSDKSKTEPSSFHSRP----KL-----ATSYIAPRNQTEQTIANILQQILGIEQIGIQDDFFDLGGDS
LIAVQVIYKLRETLQIDLPLEAILNTGTIAQLSESIQAT-----------
>tr|A0A068J707|A0A068J707_9BACT Putative NRPS/PKS hybrid synthase module B6B OS=uncultured bacterium PE=4 SV=1
--------------------VTDWLVIGDRTRVSDRLVQLKLRGDRIVSVGFGESFERVSADSFTISPEDT-DCARLVDALIEESRQIDKVVYLWTSEVD
GSF-----APRETDLGFYTPMFLAKALNELRPALDLYFVTADAQQVTGDEEIRPARALVAGVSRVCGQEMPHIRARCIDLEDFNGQAVERNIDCLLAEMS
LPEDSREIAYRGRYRWVKTTEPMPLAGQQAG-TGHLKHKGVYLITGGLGGIGRALAGFLAENYQARLVLVGRTQLPEASARVSEKLKFIGE-LEASGAQV
LTVGCDVADFEAMKVAVETATGT-FGGIDGVIHAAGLP-GGLIQLKDRQSAEKILAPKVQGALVLDALFADGSDFMLYCSSLAAVLG-GVGQVDYTAANI
FLDALALQ-RQRRGLYTVSVNWDIWGEAGMAAAAEVPAGYEKALDAGIRSAEGVEVFTRVLQQNYPLIVSTRAVLQA-----A-----------------
--------AGSARR----KPEIGNYGIEQT--LGDESEPGQGAEDAGE----AL-----PETYIAPRDELESLLCNIWQEMFGIRQIGIEDDFFELGGHS
LLAVQILSRIYESTDVKISLNDFFDAVTIAKLAEKISQQ-----------
>tr|A0A0N7ATF0|A0A0N7ATF0_9DELT Polyketide synthase OS=Myxococcus virescens GN=benB PE=4 SV=1
-----------------------VLVFLPVSRFGQSVV-LRRRGMQPITVEAGDGFA--GDSAFGLSPTEEDHYEQLLEALG---GPPGQVLHIASTGRT
GSR--QERAEATWRHGFQPLVLLARALGRRST-VRLVVATDSQYAVSGTERLLPESALLAGPCRVIPLEYFNLRCHQVDVSLGGLEQWAQHAACLVDELS
---DEPVVAYRGGQRFVQHFERLTLTAP-----PLFRPEGVYLVTGGLGGLGLAIAAEIAKTPSTRLVLLGRSGLPPRETWLQERIRAVRE-LEASGAAV
HVVEVDVSDGPGMRQALQGIRER-FGQVHGVVHAAGVPG--MIQRKDLEEARRVLAPKLDGLIHLEPLWEEGADFVCLFSSSIALSG--IGEVDYCAANA
YLDAFARELS-RRGIRALSINWGPWKWDAWQGHSVALPEAALRDTYGLTMEEGQRAWRELLS--TDQAVAPAGLKMA-----I-----------------
--------DGIGKD----F-LQE--------------SQGTQSRHPRP----PL-----LVAFVAPRDALEERIAAAWQDALGIESVGVNDNFFDLGGQS
LGALQVISRINSEMKTTLPGAT-FEAPTVAGLARLLRQE-----------
>tr|A0A0K1EKL5|A0A0K1EKL5_CHOCO Polyketide synthase OS=Chondromyces crocatus GN=CMC5_053580 PE=4 SV=1
--------------------GGTWLILSDEGGLGDALAHLCAAGQQVVTVLAGQAFSGLDTERCYLRPASFGDYDRLVAQLCAAGRRPARILHLWNVDSD
RQEGGAPTFEQAQHVGFHSLLFLMQALREHDDPIQLWFLARDLHSIERHDRPRPEKVTALGALRVIPQEYPCITCRSIELPPAEGRTGRRLLDHVLAEIA
EISSDVDVAYRGDQRWVQGFAPAPLAVPRGS-CPVLREGGVYLVTGGLTGLGAVTSVYLARTARAKVAIVDSLSLPPRATWMREAITTIQA-LEGLGVEP
LVVCADVADADALAAVMVQVEAR-FGALHGVVHAAGAR-EAALSELDVGEVARQLGPRVQGLLALEEALGARSELLVVQSSLSSVLG-GLGLAAHTAASR
CMDALAHVQASHRAATTLVINWDALRPESDRSSGEVGRDVADASAGAISAADAALALHRILWSRGAQVVSPTHLPTR-----L-----------------
--------SRWVER----SEP------------VVASPGGRASAHARP----HL-----ATPYVEPSSETEQLIARMWQELLGIDQVGVQDSFFQLGGHS
LLGTQLVTRLRQTFHVELSLRAIFEDPTVAGLALAIEAL-----------
>tr|V6MC03|V6MC03_9BACL Polyketide synthase OS=Brevibacillus panacihumi W25 GN=T458_00155 PE=4 SV=1
-----------------------WLFFANESFVSRHVHVQEDSEAEVYTIFAGTDYK--GPYEFTIEPDNPTHYEMLVKALHGSSPFPSRIVHAWHVDHD
EESNWPHAFWQQQRLGFRSLLSLTQAMSRQDQNCMISVITSGLSDVTGDEILVPEKSTLLALLKVIPQEYRNMTCRHIDIPVALANGTERLLAQLTEEIL
---VDPTVALRGARRYRQTYEAVSLPKSDT---AILRQGGVYLITGGLGRLGMLFADYLAQQVQAKLVLTGRTILSALENELR---AIIEK-WQSIGGEV
LMLQADVASLEQMRAAVAQAIHR-FGRIDGVIHTAGIMGA-DILDTDEEMIQKNFLPKVQGFYVLQDALKDVPDFTLYLSSLSATLG--LGASAYAAAHT
FLDYAARNSSHAKSSPVISVDWDGAATDTET----------------------LDAIDRIFAAKEIPLVSTRRLSDM-----V-----------------
--------KKWLTS----APDPLHS--EK---Q------STGSSYARP----HL-----KNAYVAPQTELEQLIAAIWSPLLGIEQIGVHDRFFDLGGDS
LIGTQLISRLRATFEIDLTLRM-FEIPTVAEQAALIEEI-----------
>tr|U5QK65|U5QK65_9CYAN Beta-ketoacyl synthase OS=Gloeobacter kilaueensis JS1 GN=ppsE PE=4 SV=1
--------------------GGDWLVVAAG-TSGAAIVALEQRGQTALLLPNAPDLARQRT----------------------------GILYLASDTKD
-------ELESAWQQNCAPLLPLVRGCVQIDVPPRLYLVTQGAQVIESQENPVLEHIPLWGLGRVIAQEHPELWGGLIDLDPAFDPAATA----LVTQLF
SPDDEDQIALRGDARYVARLVRQKVEGGE----LSVRADGTYLITGGLGALGLQVARYLVERGARHLVLVGRNPPSVT------AQTVLDE-LTASGATV
SPVQADVSIAGEVEQLLAEIRQE-HPPIVGILHAAGVL-DGVIDKLDWSRFERVLAAKAAGAWHLHRLTQGDPELFVLFSSIASLLG-SPGQANYAAANA
FLDGLAQH-RLSQALPALSINWGPWAEVGMAARLDAQRHPWQG--LETPPEQALAALAGLTGTGTA------SLAVM-----P-----------------
--------VRWQAF----LAQFPA---GHL---PPLLVSAASSPAAGPVLTQQL-----EQALPGERRLLVAHLRDQAARVLGIDNLDIRQPLHSLGLDS
LLALNLTRQLGAALGRSLSATLLFNYPTVEGLAAHLAEE-----------
>tr|S3IU67|S3IU67_MICAE Beta-ketoacyl-acyl-carrier-protein synthase I OS=Microcystis aeruginosa SPC777 GN=MAESPC_05228 PE=4 SV=1
---------------------------------------LKSGFSQVEFVSPDQKIG--------------ALF-QQSIILAQSSEISPNLTKNWLIFTD
VEPQEEWFASNPSPDRSILLLNLLKAIQ--PNPPQLFLVTQGAQPFKLEQPSFGFQSPLWAMGRVIALENPQLWGGMLDLDPDVDI---QNITALLLGLT
-----DHLVFRKGQGYVARLLPLK--SLE----VKIQPEATYLITGGIGHLGLELAEHLVNLGAKHLILTTRRSLPVRFLW--QISEKIRK-LEEKGASI
AVISADVGNFEAMQAIFTQIEKT-AYPLRGIFHLAGISGQ-QLKDCTLQDLEAVFQAKVKGSWNLHQLSLGSQDYFVLFSSAGAIWG--KEQGLYDTVSH
WLDALA-HFRHLQGLPATALNWALL---GIVSQD-----YEQIGIREIAPDTALRVMDAIMASNQTQVIADVDWV-R-----F-----------------
--------KNIYE-----FKGEKPL-LKN-LAIKSVQ----SDSVLHL----LE-----EMPFGERREYLLEYVSKQVRIILGIKSMDTEQGLIEMGIDS
LSSIELKNRLEKRLEVLLPTSL-FDFPNIRRLVDYLLDR-----------
>tr|A0A0K1EF47|A0A0K1EF47_CHOCO Polyketide synthase OS=Chondromyces crocatus GN=CMC5_036380 PE=4 SV=1
--------------------GRCCLLYADSHGLGARMERLRRDGYEVILVRPGESFAAEGATAFTVDPTSASDHASLLGALRRAGRVPSMILFLWGVTTP
TRAPDAARAEAAQVFGFHSLMALAQALGEVREEVRLGVVTSYMHKVTEGAALCPEKTTVLGPCRALSREYGNVSCISIDVDLPEPRQEGRLIDQILAEVS
LERTESIIAYRNGERWIRTYEPARMDRPDGL-PSRIREGGVYLIIGGLGFLGSTFAEHLARVARARLILTGRTVLPPRAMWLRRKIRTVLQ-LERLGVEV
VCMSADVTRIDDMREVVGRAVDH-FGRIDGVIHAAGST-TGSIQGTSREEAEAVLAPKLVGAVVVDDALRGLRDFILLCASRQAVLG-GARLASQSAAST
FLGAFAQRQAAVGGPLTIAVEWDPWQRSESSDDRTPGDGVESSAGHVLSREEVLDAWMRILTNPTPQVVAKREEVAR-----Q-----------------
--------RQSASS---------------IAPSKEVDESIPRSVHPRP----DL-----GTAYVAPRDPLERAIAETWEKLFGIERIGAHDNFFDLGGDS
LLAVQVISRLRGVVNMDLPGHSLLNAPTVAALAELIAQS-----------
>tr|A0A017T2M8|A0A017T2M8_9DELT Malonyl CoA-acyl carrier protein transacylase OS=Chondromyces apiculatus DSM 436 GN=CAP_6179 PE=4 SV=1
--------------------GRCCLLYADSHGLGARVERLRRDGYEVITVRPGAGFAVDGASAFVVDPASASDHASVFGALRAMNRVPSMILFLWGVAPP
VRAPDASRLEAAQILGFHSLVALAQAVGASREEVRLGVVTSNMQKVTETAVLCPEKCTVLGPCRSIPREYPNVSTICIDVDLPEPRQEGRLIDQILAEVN
LERTESVIAYRNGERWIRTIEPARMDRPEGL-PPRIREGGVYVILGGLGLLGSTLAEHFARVARAKLVLTSRTVLPPRETWLRRRLRSILH-MEKLGGEV
LLLKADVTQPEEMRAAIAEARQR-FGRIDGVIHAAGIT-TDTIQATTRESADAVLGPKLQGALVLDDALRGFRDFIILCASREANLG-GARLATQSAASM
FLDAFAQRPAAVDGPLTIAIDWDPWQFSEGPRVEEREEADSGAFAASLTREDALDALMRILTNPVPQVVARREEQAA-----P-----------------
--------RQAPGS---------------IAPSKEVEDSIPRSVHPRP----DL-----GTAYVAPRDPLERAIAETWEKLFGIDRIGVHDDFFALGGDS
LLAVQVISRLRGVVNMDLPGHSLLNARTVAALAELIAQS-----------
>tr|S4XYJ6|S4XYJ6_SORCE Uncharacterized protein OS=Sorangium cellulosum So0157-2 GN=SCE1572_29775 PE=4 SV=1
--------------------AQCCVVFADSYGLGARMERLRRDGYKVITVRPGEGFAETGEGEFTVAPASRADHASLFGALRAAGVSPSRIMFLWGVTKP
ARAPDAGRLAEAQRLGFASLVALAQGIGDARDEVRLGVVTSHMQKVTDAAVLCPEKATLLGPCEAIPRAYPNVSCISVDIDLPEPRQEARLIDQLLAEVT
LEQTEPVIAYRNGERWVRIFEPARMDRAEGL-PPRLREGGVYLIAGGLGAVGSALAEHLAKVARAKLVLAGRTALPPREAWLRRKIGAVLE-MERLGAEV
LLVTADVTRLDDMQRAVAEGLQR-FGRIDGVIHAAGAR-AVPLQRMTREEGEALLAPKLDGALVLDESLRGLRDFVALCAARTAGAR-GAGLAGQCAATA
FLGAFAQRRAAGDGPLTIAIEWDPWQRQDASRGKDPEPAADAAAEEGISRDEALDAWMRVLTSPTPHVVLKREAQAK-----Q-----------------
--------RPSASS---------------IAPSRDVEEGIPRSVHPRP----DL-----GTAYVAPRDPLERAVAETWEKLFGIERIGVHDDFFALGGDS
LLAVQLISRLRSVVNMDLPGHSLLNAPTVAALADLIAQS-----------
>tr|Q20CI9|Q20CI9_BACCE CesA OS=Bacillus cereus GN=cesA PE=4 SV=1
---------------------------------------------SVVIVDVGETFGEIHPNHYQINPKNKMDYVRLFEELAKRNVEVFHLLHAWNYCDT
VPFRSVEDLANAQYLGVFSVMFALQAIMH--AKLPLRRVTVIATNSVGLKEMNYSCSTLEGYVKTLPAEFENLQVKYIDIEGKDIQF---DTETVWKELQ
QQETIPVVLYRDEKRYKIGLEKVPML-EQKEKNIPFQQQGFYIITGGLGGLGTLVAKLLLERYSANVLLLGRTEIETNAE-KMRLLDSLKE-YEQYGGTV
QYKMCNVMDLDAMRKVVHSQEERLQQKVNGIIHLAGIIQEILIEKQTEKELHAMFEAKVYASWVLHEIVKERQDCLYITTSSARTLLPGMTISAYCSANR
FVENFAYYQR-SQNVNSYCFSWSFWNEIGMGTNLLIKNALIAKGFQLIDDQKGIYSLLAGLKGNEPNVFVGINHEKEEMAHLIGT--EEQETQQL-TIYI
TPEYLHILEEVFSIL---NREEFGGLE-KEIVILPKLPLDEYGKVDQTRLAHASDSRFGKKQHIVPRNDIEEKIAFIWEGLLNKKDISVLDHFFELGGDS
LKATQMISALKKNFAVTITQQEFFQSSTVEELASLVEK------------
>tr|R8K7G5|R8K7G5_BACCE Amino acid adenylation domain-containing protein OS=Bacillus cereus MC118 GN=II1_04398 PE=4 SV=1
AWFYEKGFVRKETEIISPKETRKIVIVGESTAFVTTIKRELEVGHHCYLVGNRE------------------AYLSILKQ---E--EINDVINLLNYEKQ
G--VDSDEIEKIRNANENGIFFISETIKAEKENLRIFTVTNNCEYSNVTKN-KYHFGTLDGFSRSVNLEL--PHIMCIRIDLD---VSENDVNGIIKEIA
AIHRDDKVVYREGKRYVDSLKPIDMTLSL-KNEIVMKKEGIYVVTGGLGGIGKEVCKLLLQQFSAKLFIVGRTALSTSPT----HLASLEELQGFS-EDV
HYINGDLSDAAFVASIAAKVEGIWGTELDGILHLAGEGSEIDCTTESEVYYEEMFAAKVFGTVNLFQLIEGKKDAMFLQFSSVNSYFGGASFTAYAAANN
FQDTFGQYVSNQGYKNAICINWSMWYDIGMSRHNTNNELMAEKGFLLLPMKQALYSLLAVLRTGVNNVFVGLDASKSNIRKSIKQ-KKELEIEAII--YH
TDE----VS----DFT-IEAKK-----HVSFVKVDEIPIDEKGCVQIGELQDLHKNVGKTENFQEPQSEAEKTLAKIWRDVLQVNKIGRDSNFFELGGHS
INATQLVSKIYSVCRVRMPLKNVFQYTTLSTMARVLEELLDEV-------
>tr|N0D736|N0D736_9ACTN Uncharacterized protein OS=Streptomyces fulvissimus DSM 40593 GN=SFUL_6815 PE=4 SV=1
PWFFVETEQPR-----IPAADGQPVTLGGGPAERAEVTRVL---SEALSVRADG-------------------------ETERPDGTVDAVVDLRLTRA-
--GWDGRAVYELISDTT-----KAIGAHAGPAKLRIALVTAAGQAHDDL--ARAHLGALQGYVRSVNAEAGEPVVVWCDLDAV----DEANVNLLARELV
TYAAAPAVAYRSGVRTERALSPAPRDPAGV--PAEIKEGGQYIVTGGLGGVGRELCRFLAEKYGARLVVVGSTPAEQLDE----SRSALRALE-AR-TRT
RYVSVDLASADAPELLRAALRSAAEGRVDGAFHLAGLGGEALGARVDDGRLARYTALKVHGMAALAGA--LTKDALLVGFSSVNAYFGGAGYAEYSASNS
ALNASVRSLRDQGYRRALSLGWSAWSGTGMSGGAGASMPIERRGFLSLDVDLALESVDIAVRRNQPVTYIGLDGAHPDVASHVRR-KPGWEPVPRY-FYV
AE--SELSA----EIT-ELAP------ALRSSRVAQIPRKGDGHVDTVRLLQ---TVSSTTAAAPPETATEQRLAALWEEILGTENLARDDDFFMLGGHS
LMAARLANDIRRAFGVTVALHEFFKSSRLSAVASLIDEKS-AA-------
>tr|A0A0F7CQC3|A0A0F7CQC3_9ACTN Vlm2 OS=Streptomyces xiamenensis GN=SXIM_47770 PE=4 SV=1
PWFFTETTHPR-----VPAPAGRPVDLGGSPADREAVGRTL---AAALTVVSGP-------------------------AAEHPTETLDAVVDLTLTRD-
--GWDASDVLRLITATA-----ERQAAEPGRA-RKILLVSVGDRGRDAA--ARAHLGALQGYVRSVHGDAHDPAVIWCDLDTL----DEANAAALAAELT
APSGAAVVAHRAGVRSERVLAPAPAVAPGTAAAPVLTAGGTYLVSGGLGGVGREVSRFLADRHQARLILVGSTPLDRLDA----ERRELNALA-AR-TEV
RYLAVDLAAPDAAARLREA---AGPGAVDGAFHLAGLG--TLGQTVDAERLARYTAVKVGGLFALAEV--AGPAAPLIAFSSVNAYFGGVGHTEYSASNS
ALNEAVRVLRAQGHRAAVSLGWSAWTGLGMSKG--NTVPIERRGFLSLDPDLALESLLLALGHDRAVTYVGLDGAHTDVAAQVRH-KPGWRLVPTY-YYA
AD--GEIAA----EIA-ALAA------GAESALVPQIPRRRDGQVDTVRLLQ---SAGTRATGDRPATETERRLAAVWERILGTEDLARDDDFFSLGGHS
LMAARLGNDIRAEFGVTLALHEVFEDPTLSAIARVIDEKS-AP-------
>tr|A0A0M4DS39|A0A0M4DS39_9ACTN Uncharacterized protein OS=Streptomyces sp. CFMR 7 GN=ABE83_01785 PE=4 SV=1
PWFFVETDQPR-----VPAADGRPVVLGGDPAERAEVTRVL---SRDLAVQAPG-------------------------E--APEGTLDTVVDLRLTRA-
--GWDGRAVSELIADTT-----KAIGAH-TAATLRIALVTVAGRAQDDL--ARAQLGALQGYVQSVNAEAGEPVVVWVDADTV----DEANVALLARELV
AYAPAPAVAYRAGARTERALAPAPRDPAGV--AAGIKEGGRYLVTGGLGGVGRELSRFLAEKYGARLVLVGSTPAGQLDG----ERAALKALE-AR-TDV
RYVSVDLAAADAPDRLRAALRSVADGRIDGAFHLAGLG--GLGARLDADRLERYTALKVRGMAALAGE--LAKDALLVGFSSVNAYFGGAGYTEYSASNS
ALNASVRTLREQGYRRAMSLGWSAWTGTGMSGGAGAAMPIERRGFLSLDVDLALESVDIAVRRNQAVTYIGLDGTHPDVASQVRK-KPDWALVPRY-FYV
AD--SELSG----ELT-ELSP------ALVTSKVDRIPRKADGHIDTVRLLQ---AASTTAAAAPPETPTEQRLAALWEAILGTENLARDDDFFMLGGHS
LMAARLANDIRREFGVPIALHEFFKSSRLSAVAALIDEKS-AP-------
>tr|A0A0B4S4N4|A0A0B4S4N4_9BACI Peptide synthetase OS=Bacillus sp. WP8 GN=QR42_01975 PE=4 SV=1
DWFFKRIWAKENIGPTQSFA-DHVLVFEDEKGLYQSLYVQFQKNQPYISVRKGHEFLRLSKGMYQINPRIKGDYVRLIAALEADELKTGRMLHLWNVSDK
EDIVDPAHFKELHASTNQSILYLYQALRQNKEPIRFVVVTKGGQFVQPEDDLHVEKTPLVGLLKTIPQEWEGAEVSHLDIEAE---NVEQDAKHIADELS
AIHIKAEVSYRNGDRFVPKLEKVNMMEAP-QTEGFLEYEGLYLLTGGLGGIGFELSKQML-QFGLKLVLIGRTSLEGSLE----KKEAFSQLKGF--GDV
IYVQADVTNLCDVEQAIYEAEKHFVQSIRGVLHLAGAGQQADLAHTSEEDFTKEMSGKADGAWVLQEAFKYDQTVPLVFFGSVNGFFGGTTFGAYSAANS
FLDGLAHALNFQQGRRAISLNFSMWDNLGLSKGHTGAALTVRKGFQLIGKKQGLHSLCLGVRLNEAHLFIGLDGANPDIAGYLQP-APIPVFEKKL-FYT
VQPGKEVVE----EIK-SVAEG-----KWDIQQVQEIPKKQDGSIDHEALKLNHDKNVLSLEKQLPETKTEQVLAAIWEDILDVDRVYKEDQFFDLGGHS
LKATQTISRINHEFSMKAPLKILFESTHLAHLAQMIDDIKGAP-------
>tr|W6I0M6|W6I0M6_BACPU Nonribosomal peptide synthase OS=Bacillus pumilus GN=BPJ03490 PE=4 SV=1
DWFFKRTWAKEHIGPSQPAA-DQILVFEDEKGLYQSLYAQFQRNQPYVSVKKGHEFLRLSKGMYQMNPRIKGDYVRLVAALEADELKTGCILHLWNVTDK
EAIVKPAQFTEMHARSNQSILYLYQAWRQNKEPLRLVVVTKGGQFVNAEEDLHVEKTSLVGLLKTIPQEWEGAEVSHIDIEAE---QVEQDAKHIADELS
VIHIKAEVAYRKGHRFVPKLEKVDMMSVP-QTEGFLEYEGLYLLTGGLGGIGFELSKQML-QFGLKLVLIGRSSLEDNLE----KKEAFSQLKDL--GDI
IYVQADVTDLADVERTIYKAEKHFGQSIRGVLHLAGAGQQADLAHTSEEDFTKELSGKADGAFVLQEAFKHDPAVPLVFFGSVNGFFGGTTFGAYSAANS
FLDGLAHTLTFQEGRRAISLNFSMWDNLGLSQGHTGAALTVRKGFQLIGKKQGLHSFCLGARLNEAHLFIGLDGANPEIAAYLQP-AQIPTLEKKL-FYT
AMPGKEVVE----EIA-NITKD-----GWDIQQVQEIPKKQDGSIDHEALKLNHHKHGQSFEKQLPETETEQVLATIWEDILDVDRVYKEDQFFDLGGHS
LKATQTISRINHEFSIKAPLKILFESKHLAHLAQLIDDIKEVP-------
>tr|A0A0P7GG95|A0A0P7GG95_9BACI Non-ribosomal peptide synthetase OS=Bacillus sp. NH7I_1 GN=AKG37_14135 PE=4 SV=1
DWFYKRIWAKELISPTQPST-DHVLVFEDEKGLYQSLYAQLQKNQPYISVRKGHEFLRLSKGMYQMNPRIKGDYVRLVAALEADELKPGCMLHLWNVSDK
EDTLDPAQFKERHAGTCQSILYLYQALRQNKEPIRLVVVTKGGQFVQPQDDLHVEKTSLVGLLKTIPQEWEGAEVSHLDIEAE---NVEQDAKHITEELS
AIHLKAEVSYRKGHRFVPKLEKVDMLEAP-QTEGFLEYEGLYLLTGGLGGIGFELSKRML-QFGLKLVLIGRTTLEGSVE----KEEAFSQLKGL--GDV
IYVQADVTNLADVEQAMYEAEKHFGQSIRGVLHLAGTGQHADLAHTSEEDFTTEMSGKAAGAWVLQEAFKYDPTVPLVFFGSVNGFFGGTTFGAYSAANS
FLDGLAHALTFQEGRRAISLNFSMWDNLGLSKGHTGAALTVRKGFQLIGKQQGLHSLCLGARLNEAHLFIGLDGANPEIAEYLQP-ASIPVFEKKL-FYT
VQTDKEVVE----EIT-SVTEG-----NWDIQQVQEIPKKLDGSIDHEALKRNHHKSVKSLEKHLPETKTEQMIAAIWEDILDVDRVYKEDQFFDLGGHS
LKATQTISRINHECSIKAPLKILFESRHLAHLAQMVDDIKGGA-------
>tr|M5RF77|M5RF77_9BACI Amino acid adenylation domain-containing protein OS=Bacillus stratosphericus LAMA 585 GN=C883_1231 PE=4 SV=1
DWFFKRIWVKENIGPSQPVSTDHVLVFEDEKGLYPSLYTQFQMNLPYVSVKKGHEFLRLSKGMYQMNPRIKGDYVRLVAALEADELKIDRMLHLWNVSDK
EMIASPAQFKELNASTSQSILYLYQALRQNKEPMRLVVVTKGGQLVKPQDELHVEKTSLAGLLKTIPQEWEGAEVSHLDIEAE---NVEQDAKHIADELG
AIHLKAEVSYRHGQRLVPKLEKVNMMTAP-QTEGFLEYEGLYLLTGGLGGIGFELSKQML-QFGLKLVLIGRTSLEEDRE----KEASFSQLKDL--GDV
LYVQADVTNLCDVEQAIHEAEKHFGQSIRGALHLAGAGQHVDLAHTTEEDFVKELSGKADGAWVLQEAFKHDPSVPLVFFGSVNGYFGGTTFGAYSAANS
FLDGLAHALTYHEGRRAISLNFSMWDNLGLSKGHTGAALTVRKGFQLIGKKQGLHSLCLGVRLNEAHLFIGLDGANQEIAEHLQP-APIPHFEKKL-YYT
VQSGKEVAD----NIT-GIIEG-----KWDIRQVEDIPKKQDGSIDHEALKQFHHKHAQPFEKQLPETKTEQVLAAIWEDILEVDRVYKEDQFFDLGGHS
LKATQTISRINHEFSIKAPLKILFESKNLAHLAQMVDDINGAP-------
>tr|A0A081L7S5|A0A081L7S5_9BACI Peptide synthetase OS=Bacillus sp. DW5-4 GN=BA70_09625 PE=4 SV=1
DWFFKRIWAKEHTGPSLPASTDHVLVFEDEKGLYQSLYAQFQTNQPYVSVKKGYEFLRLSKGMYQMNPRIKGDYVRLVAALEADELKTGRMLHLWNVSDK
EKIVDPAQFKELHESTSQSILYLYQALRQNQEPIRLAVVTKGGQFVKPQDDLHVEKTALVGLLKTIPQEWEGAEVAHIDIE---AENVDQDAKRIAEELS
AIHMKAEVAYRQGHRLVPKLEKVDMIEAPQT-EGFLEYEGLYLLTGGLGGIGFELSKQM-LQFGLKLVLIGRTPLEE--------DGEKEKAFTKGLGDV
IYVQADVTHLSDVEQAIYEAEKHFGQSIRGALHLAGAGNVSTLAHTSEEDFIKELSGKADGAWVLQEAFKHNPTVPLVFFGSVNGFFGGTTFGAYSAANS
FLDGLAHALTFQEGRRAISLNFSMWDNLGLSKGHTGAALTVRKGFQLIGKKQGLHSLCLGVRLNEAHLFIGLDGANPEIAHLQPASMPRFKKKLYYTVQP
------GKEVNLDDITG----VTVGDWDIRE--VPDIPKKQDGSIDHEALKLNHYQNVHQIEKQLPETKTEQVLAAIWEDILEVDRVYKEDQFFDLGGHS
LKATQTISRINHEFSIKAPLKILFESKHLAHLAQMVEDI-----------
>tr|R8CX55|R8CX55_BACCE Amino acid adenylation domain-containing protein OS=Bacillus cereus HuA3-9 GN=IGA_03667 PE=4 SV=1
NWFFRKTWIKRQLSVGIQKTIDAALIFGSHEGVAGNLASHISGGGKAVIVEVGKEFLQLSEDHFIVNPNRQNDFEAVLSKIK---VTPTYFVHAWQCDVE
SNM----------ELGLYSLISLFNAIDKGISPLNLTLITKYAWGVLETELANPMAAAMTGILKTAEQERIGLQCLHFDFD---SLAPALVAKAAYQELM
HGDMEKELAFRKGNRMIPKLINAELLKDVST--SPIKREKLYLVTGGTKGIGSLTVKMLIEEFAAKVLIVSRSKVEK--------DTEFAKYIEKHKKKI
LFVQADVANLVAIADAVKKAEDYWQEPILGAFHFAGVMEERLIEEESPESIATVIKGKVMGAESLIEIFSSRPDSFLMLSSSVNGYFGGFKAGAYSAANA
YLDALPSAVG-ENGPKIYSISWTQWEEIGMNKDSLLVELSKAKGFMSISASQGMASLLATLCQSSGNMIVGLNPNKHYVAHMILPVRPGDLLQCYYSGEV
------QPNRILGNLSKYDEFGTVFDFNIIW--LEEMPVDAMGAPDKSLLKKAINKEFTSSKFREPQSNTEKKLADIWKEILNANKIGVADNFFELGGNS
LLATQLVSRIRSHFKIELLIESLFKNATLGALGEEIDSK-----------
>tr|G9CIA1|G9CIA1_9NOSO NpnA OS=Nostoc sp. 152 GN=npnA PE=4 SV=1
NWFYRQIWRQKAPVTQISAINGNFLVFIDQLGVGEYLGEFQKHGQKWVGVEVGVDFRQLSSNRYEIAPNNPEHYQLLLSALAANNFQIDNILHLWTYDAR
ISESSLESLEQAQTLGVYSLLFLVKALAKFDRAIALTTVSSYTQFTSHSDEIAYEKSPLVGLLKVIDQEIPGLTSRHLDLSVDEPAV---NAGQILQEIS
VLPCESEVAYRQGQRWIPRLEKVDFSPQS---KPAFKSGGMYLISGGLGGVGVEIAKYLLKHYKARLLLVGRTHLPEKSDLHTQKIAVYEE-LEQLGGKI
IYEAVDVCDLPRLQQIVEQAQSRWGCELDGVLHLAGTYQERSLLEENHQSWSTAIRAKVSGAWVLNQLLKDYPQAAMISFSSVSRCLGGATVGTYVAANQ
FLESFAHYQR-SQGLKSYCFSWSLWDAIGISQDQQRSKLAQTKGYCAISARQGLYSLLIGLHHNQAHLLIGLDGSNRHIRGYVEDTY-ALEKLTA--YFT
VSDNSSIEERLSQL---RVRDRFGTPSTCNFVQLQKMPLTTTGIIDRDKLIK--GDLREPSEQAQPTSDIERQVAQIWQEVLGLEEVGIDDNFFELGGHS
LLLVQAQSKLQESFQIPVSIVDMFKYPSISALAKYLSQG-----------
>tr|A0A0D6WVN2|A0A0D6WVN2_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. MBRL 601 GN=SF12_07640 PE=4 SV=1
QWFYAPSWQQTAPAPPADAAAHSWLVFADETGVGGELADLLELGATVRTVRAGSEWSRKGEGVYVLDPGSPEHYTRLAEALREEGSPPDRVLHCWSVGSD
ADGTDPQNVRALLDRGFHSLLHWAQATESGSVPQRWDVVSSEVCSVTGDEALCPPKAAVQGIVRVLPQEYPSLTCVHLDLAGGQTAPA--AVDAILPALS
LPAGERTLALRGRRWWAPTFVAAEQPRRDS---APVRADGVYLITGGLGKIGMLMARALAERERVRLVLLGRTGPEATRD----LIRGVRAL-EELGSEV
MVCAADVSDPVRMREVKEAVVQAYG-RVDGLLHCAGTTGAEAVADLGERESAWHFDPKLYGTYVLDEVLADQELDFALLCSSIASLLGGLGFAAYAAANA
VLDAFAQRHHG-AGQPWSSVNWEAWRFTAAPRDEAIGSAVQALALDPDEGRRVTDALLAAV----------------------------PQAQVVVS---
TSDPVRRREQWVA---------------P---------AAEAAMPRQQHERPNLR-----NPYVAPDSETERQVAVIWQELLGVQSVGVHDNFFELGGSS
LLGLQVVHRLRQELSLPVPLTVVYEGPTVRALGGLVDD------------
>tr|G6FNP7|G6FNP7_9CYAN Phosphopantetheine-binding protein (Fragment) OS=Fischerella sp. JSC-11 GN=FJSC11DRAFT_0494 PE=4 SV=1
DWFYIPSWKRSLLPQS-CR-DEKWLLFIDECGLGCELANRLKQGKNVTTVKVGEKFTKLSEGIYTINPYNYEDYDTLLTELIALNETPQNIAYLWSISSL
DT----PKLGDF--LEFKSLLFLIQTLKQKTERLQIWVVSNQIQEVNGNETLDPEKATVLGLCKVIPQEYPNIICRNIDFVLKDSR-DFNILDQLLSEFS
ALSSDTVVAYRHNYRWVQVFEPVHLSAVEEN--TPLRKHGVYLFPGGLDSFGVVIAKYLAKTLQAKLIFIDDSTEDEVSG----KISKLQAL-EELGAKV
LVVRADPTNSEQMYH--SLSPENIG-QIHGVIYSTGITRENVIPEIGKTDLEQLLDAQLRKYVVLEQVLQNRKLDFCIIFSSLSSILGGFGLGLYSGINQ
LTDSFTQRHNQTNSFPWISINWDKLQLNAIQEQKTGQTSGVELAITETESVEVFKRVFSIG----------------------------EGTQVVVS---
TIDLKARWE-HT---------------------------LDPGVCSSRYSRPNLS-----NSYIAPTNELEKQITEIWQEVLGIAQVGIYDNFYELGGDS
LIATQLVSRLRAKFPVELPLRELLLQAMIPIKQAEMIE------------
>tr|A0A0A6RNC8|A0A0A6RNC8_9GAMM Uncharacterized protein (Fragment) OS=Candidatus Thiomargarita nelsonii GN=OT06_48620 PE=4 SV=1
DWFYLPSWKRSVLQTS-EVLVYTWLVFIDECGLGSQLVKRLEQAHDVITVKIGATFTQLGERHYSLNPAQREDYDALFS---ALDKTPENIVYFWPVQPL
NC----PSYSEVENLCFYSPVFLAQALEQGMDEISISIISNNMQQVAGETVLYPEKATLLGPVKVIGQEYPNLTCRSIDLVLPNAW-QEKLIDQLFLELS
AKVYDLVIAYRDNHRWVQTFEPVQLKSPSVP--RILRKNGVYLITGGLGGIGLVLAEHFAKTVQAKLILIGRSTDNAISH----KIKKLQTL-ETFGAKV
LVVSADVANQPQMQEVFSLARTQFG-QINGIIHAAGVPCGGM---KTRTTTAPILATKVRGTKILADLSKDISLDFMVLFSSLSSIRGDFGQVDYCAANA
FMDAFTHQLQH----FSICINWDTWQEVGMAANADSHTENLQRGILPSEGIEVFERILANA----------------------------L-PQVLVS---
TRDFDFQFSTSD---------------------------SDN---NKSNQRPQLQ-----NAYIAPSNDIEQTLADIWQKLLGIEPIGIHDDFFELGGHS
LLATQVISRMRDAFGVVLPLPTFFEVATIAQ----LAE------------
>tr|A0A0N0SDQ8|A0A0N0SDQ8_9ACTN Uncharacterized protein OS=Streptomyces sp. WM6372 GN=ADK52_07360 PE=4 SV=1
QWFYAPSWQREALPAG-EQ-TRHWLVFADAVGVGEAVAGRLRAGAAVTVVEAAGAWADRGDGRYAVDAGNGSDYERLIDTLRNPAGAPTRIVHSWNVTAP
GE-------EGSLRHGFESLILLAQALRHASEPRRIWVLSNGLHSITGAEVLSPLKATLLGPCRVLPRELPGTACRSVDLDYGAALTERELVR-LMAEAE
PERGPETVAHRGGHRWSQHFVQQRLPRGDRS--PVVRKGGVYLVTGGTGGLGLALAGHLAA-AGARIALTSRTGRSRLSN----VVRELVRL-RDAGAEL
LVCQADVSDRAAMDEAVRQTVGRWG-GINGAFHMAGVPSGGL---KDLRAAAEVLLPKVRGTLVLEGALAGQELDFLVLFGSNGANMGSAGQVDYCAANC
FLDAFAQDRGRTR--RVIAIDWGPWREVGMAADAA-ADQMDQRAMSPSEGLRALDTILAGV----------------------------SEPQVVVS---
PAELSALFENAFS---------------L----------QDTEPRGAVHERPDIL-----TEFVAPRTDAERTICEVWQELLGIEKVGIQDSFFDLGGNS
LIAIQVVSTVNTRLGAKLALGDLYEGLTVSHLAAVAEK------------
>tr|S9Q7I8|S9Q7I8_9DELT Uncharacterized protein OS=Cystobacter fuscus DSM 2262 GN=D187_007048 PE=4 SV=1
GGFSLPSWRPTLPPSAAWD-ACWWLLLPGPEGIGARLKQRLEAGQRVILLTPGPRLAQLGENHWSLQPAEAADYDLLLRLLLPQGLAPDRVLHLWSLLPP
RNGELEAAFEPAQEGGFQSLLFLLQALRQA-RPLSLVVLTHRM-QALGEESPCPERATVLGAVRAASRESPHVTCRSVDVNLPAPGSWQRLADWLLSECA
AASSSEDVVYRGQQRHVRAFTPIELPTAAQASALSPRERGVYLVLGGFGTLGSSHAEALARHVRARLVLVSRSLGDPLSR----RIRHVRAL-EALGAEV
RVISADVGDRDQLQSALEETLAHFG-ALHGVVFCVGSMNASLLADLTPDDVRVLFQSRVRGLYALEEVLRGRPLDFCLLASSLAAVHGRGASAAYAAAMN
FMDAFALRQAQRSPVPWVSVDWDGWASDDADALHS-VAPLGSRPITAAEGAELFTGVLSLG----------------------------DVARVAVT---
PRAPSAPATAQPP---------------P---------SAEPPSAARKASRPDLD-----TAYVAPRDEVEESIAKVWESMLGITGVGIYDNFFELGGDW
RTGMTVMTQVREKTGVPLPPVSLQEGPTVELLAQRLRA------------
>tr|K9U2R0|K9U2R0_9CYAN KR domain protein OS=Chroococcidiopsis thermalis PCC 7203 GN=Chro_3673 PE=4 SV=1
-----------------------------------------------------------------MNPQQAPDYEALLQALHARQQFPDSVIHLWTIAPY
TQALDVEIFERSQVRGFYSLLFLTQALKQNGDRLQLTVVSNHLHGVTAEEIVSPEKATVLAAVKVIGQEYPNINCRSIDVMISDAEKLVLLGEDLVSRKV
DVSDDVAIAYGKGQRWVQAFESVKLPKTNTS--ALLRTGGVYLITGGLGNIGLVLAEYLAKSVKAKLILTGRAVDDEISG----KIRKVQRL-ETLGARV
MVAAADVADIQQMQAVIAQAESQFG-RLNGVIHAAGVLGESSIEKIEKIHCDRQFQSKVYGLLVLEKILQEKQLDFCLLMSSLSSVLGGLGSVAYAAANL
FMDAFIHQQKRNNSIPWIGVNWDIWQFKNNKNIFT-SASLAEFAIAPEEGMDALQRILSQD----------------------------EFEQVVVS---
TGDLQSRIDRSI---------------------------REPDSLSSAYSRPNLP-----NCYVAPRDRLEQIIANLWQQLFGIEQVGIHDNFFDLGGES
INGMTFINQFQKQLGQIVHISAIFEAPTVNEFAAYLQK------------
>tr|H0U4L7|H0U4L7_BRELA AMP-binding enzyme family protein OS=Brevibacillus laterosporus GI-9 GN=BLGI_283 PE=4 SV=1
EWMYARKWEERPISVLSPLPQETYLIFRDKLGLGDQWSALSQNGSTMIIVDQGESFKKRGEFHYEINQHEQKDYQLLCEELKKESVTIHHVLHLWTYQED
LAKKELSYLKESQFLGSFSLIFLLQALHKVGMPKTLTFVSSNVFSLENPEHSAYEKATIPGIIKTMKHEFPNTIAKFVDIDTN-HPPYHPLQ-ALQAEQG
LPDEESVVIYSKGKRFVPKLQQVNLQEANKKPL-PLVEKGFYVVTGGLGGVGKQIAHYLIQKLDANILLLGKTALPGATDTQSEALRELEKLTTR-ENQI
IYKSTDLSDVTVLEEAI--HESMLGEKVDGIIHLAGVYYEKPLLEETIESLEHMYESKVAGTYLLGKLVEKYPEAILVTSSSSSGLLSGYGVGAYTSANM
FVETFTDYVAQRDGV--QCFAWSLWNDIGLGQQFDMKDLLIRKGHQPISAQKGIFSFEVGLMLEHNMLYIGLNKGVSEIATLCSEVVE--KELVTTVYFS
TTHNQFSLSEMYNTI----RLH---------------TIDEKGHSTKVIFRQ-VDQLHSDAEDHSNNRRVEEEIKQLWSEILQVDQLQAFDSFFDLGGSS
LKATQLLSSVQSRFGVAIPLKVFFENPTIKGLIHRM--------------
>tr|A9AV11|A9AV11_HERA2 Beta-ketoacyl synthase OS=Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785) GN=Haur_3967 PE=4 SV=1
DWFYRPEWAPAALNAPTNDSKQRWLIFVDAMGIGAGVRQRLAEHGEAVTVTIGEGFKRLDTHHYELAPTRLADYLDLIAAIQGQDPLPTHVLHLWSLTPL
A------GIAAAQDYCFTSLLNLARAFEAQTDSIHMLVVSKGMQAVDPSDIPDADNATLLGACTVIGQENTSIIVRSVDLDVDLDARHDGYAAGLIAEGQ
SGSHDLHVAYRDGQRFAERYVPLRLE---ALSQPILRPGGVYLMTGGLGGVGLILAEHLARTAQAKLVLVGRQGLP--ERAAWDALREHVRTIESAGGVV
EVVAADVADPEQMRRAVAIAE-ARFGPINGVLHAAGISDDTAIQTLEQATYAAHFQPKVYGLYALEAALGDRPLDFCVLCSSVSSVLGGLGFAGYAAANC
FIDAFTQRHNRTHAVPWVSVNWDTWHLRAGQ--DVT---GLTVAQYEMSPAEGAAAFERVAAARGH--------------------------SQIINS--
---TGDLDARIRQW--------------VR---LESIRNDAAVAP-APAS---NGRPELSTTYVAPIGEYEQRVSAIWQHVLGIDEIGLHDNFFDLGGNS
LIALQLIARLKKEFKTHISAVALFEAPTVSTMAQYLRPE-----------
>tr|A0A066TQ73|A0A066TQ73_9PSEU Uncharacterized protein OS=Amycolatopsis rifamycinica GN=DV20_37350 PE=4 SV=1
VQVLTPSWRPQPA--PAAGTTGRVAILPDSGGVAAALAELLGDVAVAEA-DTVVDLSVLDLDDEV---AAVHAVSRTLTAAAGDGSRA------------
---------------------------------VRVLLATRTGQAAGNGGRLRPAQAAVAVLPVVANQEYLNLEAGTVDLDAAHSPA--EAAAVLAAELR
-SPGTPLVAYRGDRRLVPGHRPAE-----AAGAPAIRPGGSYLITGGLGEVGLTVAEHLVTRGARRLVLAGRSGGT--GPA--------VARLRALGAEV
HTPRVDVGDLTAMRALLAE---HR---FDGIVHAAA---DSTLSELDEAAIARHFAAKVGGARVLAAALDEDRPEWTLLFSSTSALLGGVTFGSYAAANA
ALLAEA-----HGRPGWIAAAWDTWPGTLER-DGRL---GATMARHAMTRTQALAAFDRLTALPGP--------------------------AVI-VA--
---AGGLDERLPGA--------------AK---VTTTTTAD-----RF------PRPDLPQPYTPPMTATERGLAEVWSSVLGVEPVGTRDNFFDLNGNS
LLALQMLALVKERFGVAIPTVTLFELPTVQALAATLDHQ-----------
>tr|A9AV10|A9AV10_HERA2 Beta-ketoacyl synthase OS=Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785) GN=Haur_3966 PE=4 SV=1
DWFYQPAWVRAELLGAP-VKPGCWLVFADQHGLGNAVGQRLILAGRVVQIEAGSDFVQFDEQHFQIRPGQIDDYQNLLKTAIGAGYLPTHVLHLWSLAPA
A------GRAAIQEYGFTSLLNLAFALGSQDDPVELLVATASIQAVDPSDLPDADNATILGACTVIGQENLSITVRNIDLSLPADLNSELPVAALVAECQ
KQNSDLHVAYRGNQRFVQQYQPLRLE---VPESPAVRPGGVYVITGGLGGVGLVLAEHLARTAQAKLVLVGRQGLP--ERAAWDALREHVRMIEAAGGSV
LVVAADVAMVAGFQRVIAATE-QQFGSINGVLHAAGISDSTAIQLLEQATYAAHFQPKVYGLYALEAALGDRPLDFCVLFSSISAVLGGLGFAGYAAANC
FIDAFTERHNRTHAVPWVSVNWDTWQLKVGQ--DVI---GATVAQYEMSPAEGAAAFERVAAARGH--------------------------TQIVNS--
---TGDLDARIRQW--------------VR---LESVRADAAAAA-DTAV---QTVPR---GTPLSSSEYEQRVAMVWQQILGIDEVGIDDNFFDLGGNS
LVALQLVTRLKKELKTQIPMVALFEAPTVRAMSQLLRPE-----------
>tr|A9AV08|A9AV08_HERA2 Beta-ketoacyl synthase OS=Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785) GN=Haur_3964 PE=4 SV=1
DWFYRPDWAPTALGAP--AAPGRWLILPDAHGLGTAVAASLRAAGTVTL---------------AAGPADAAAYGSLFATLRADGGLPSHILWLGGLTPL
D------SAQAAQATGYYDLLQLAQAVSAQDEAVQLVVVTAGMQAVGANTIPVAEHATLLGLATVIGQENLTIRVRSVDLAVADDA----AVGLLAAECL
ATSDALRVAYRDGQRLEETYQPIRLE---APGSPVVRSGGVYVITGGLGGVGLVLAEHLAQTAQAKLVLVGRQGLP--ERAVWDALREHVRMIEAAGGVV
EVVAADVAQVADLQRVLATAE-ARFGTLHGVLHAAGISDPQAISTLGPKECEWHFQPKAYGLYALEAALGDRPLDFCVVFSSVSSVLGGLSFGGYAAANS
FMNAFTQRHNRTHAVPWVSVNWDTWQLKVGQ--DVI---GATVAQYEMSPAEGADAFERAAATRNE--------------------------PVIINS--
---TGDLDARIRQW--------------VR---LESVRAAEAPSG-EL------LQSSVASGEMLSLNDYEQRVAAVWQQILGIDEVGIDDNFFDLGGNS
LIALQLVSRLKKELKTQISVLALFEAPTVRAMTQLLRPQ-----------
>tr|A0A0H0SSK8|A0A0H0SSK8_9BACL Polyketide synthase OS=Brevibacillus formosus GN=AA984_04320 PE=4 SV=1
IQLKNVVWTRPIVVQPAENGEITFEIYSEIDAMDAVMLHNLPSQGDTLYVGEGKVSVSEMENPFVLHPSLMDSYVRYSANSSADDKVALMLSAVWDVTPV
E------KGIAGQDQGVILCFRTIKALLRGRKELGWSIITVQSQPVRHTDVVNPCHASIHGLIGSMAKEYPNWKIRLLDVEAESEWPLDDMV-----RLP
RDRQGRPWVYRQGEWYRQQLLTVD---HPPIDQTRMKQGGIYVVVGGAGGIGEAWTEYMIRTYQAQIIWIGRRQKN--EEIQ-------MDRLAAYGPAP
DYIAADAAQQNALQQAYEQIK-QTYQRIDGVVHSAMVLVEESLENMQEVGFRAVLSSKVDVSVNIASVFENEPLDFVLFFSSLMAVTKAPKQSNYAAGCT
FKDAYAHQLTQAWPCAVKLINWGYWSSGQVEHQEMVETRLEEIGIGLIQPPEAMQAIETLLAGAML--------------------------ADVVISFQ
VINAGEFDLIIRQT--------------LRNCNLQNVRKDLAEGPSVPLEASTLPIPANA-DRGISTDMLRAYFKQLVGETLKFDQIDSSAALEEYGIDS
IMIVQMTNVLRKKLH-QISTTLFFEYQTIDALVEHFMTT-----------
>tr|A0A0F6Y0Y3|A0A0F6Y0Y3_BRELA Beta-ketoacyl synthase OS=Brevibacillus laterosporus GN=EX87_22650 PE=4 SV=1
EWFYLPTWESAPFTKQEKQENKKYLIFIDEENVGSELANRLRKSGHVSIVRSGAAYSQKSEGEYVIQASEENNYKQLFQNLRYHDTLPDEIIHMWNVNKD
E------IGIASMEFGYYSLIHLVKAISEQIEPLQISVITSQMQKVTDTDRVQPEKAMLLAPVKVIPQEFQNIRCRSIDIAGTDEQSLKDVIEPLFTELT
SKIVDTVIAYRNQGRYVRTFSRVPVE---EATVPQLRKKGVYLITGGLGGIGTKLAEYLAKSIQAKLVLVGRTQLP--PRAEWEVLANNIQQMEEYGAEV
LVISADVAHENQMRDVIAQAE-DKFGSIHGVIHAAGILRVKSMERITKEKCEEQFQPKLYGTLTLEKVLRDKPLDFCMLVSSLSPILGGLGFVAYAAANL
YLDAFAEKQSLLNPNRWISVNWGDWQYTGKENKTFV---SESIEMLEMTPTEGIKTFQCVLGLKGV--------------------------HQVVIS--
---SGNLYSRFNQW--------------IN---LEALQEERSGMSGKGKAP-KQQKRIQSMKNRTRMAEIEQLISEIWMDFYRVGSVNPAENFFQLGATS
LDIIQIHNKIVKGLEKHIPIEAMFEFPTIQLLAKHLSGD-----------
>tr|A0A0B2B809|A0A0B2B809_9ACTN Amino acid adenylation protein (Fragment) OS=Mumia flava GN=LK11_44245 PE=4 SV=1
HPLYHVVWEQQAALAQVAADASPWLIFADASGVGERLAVLLRARGSCSLVRPGPDYVAGAEAGWQVAPERPDDFVRLLNETAAPG---QRIVFLWALDEA
V------GE-------STALLHLVHALVGWSTRPRISVVTRDAVEAGEAGLAQAALSGLARGAMIEHPEWFGIA---IDLDPAAPE---DETHALLQEML
GESREEQVALRHGARHVARLSPLAQA---ETAALPVDPDAAYLITGGFGALGLHTARWLAARGAGTLILVGRQGAA--SDESQRA----IAELRERNVTL
RCERLDIADPAAVAAFFAALR-RDGVPLKGIVHAAGIV----IMQVERDELDAVLQPKVAGAWLLHQQSEHFPLDFFLLFSSIASAWGSREQAHYSAANR
FLDALAH-HRRGQGLPALSVNWGPWAEGGMTEAEAL---LRRVGIRSLAADRALDVLNRLPAVPQV--------------------------AVVDIDLA
-LFQGSYEARGPKP---------------F---LDRVRVAKSAPS-APAMP-ALSDASPRERKRLLADSIDRA----VAQVLGAGTLDRDLGFFEMGMDS
LMALDVRTHLENALGIPLSVALLFDHPTVNALADFLAEQ-----------
>tr|A0A0F6FHU7|A0A0F6FHU7_BACTK Short chain dehydrogenase family protein OS=Bacillus thuringiensis subsp. kurstaki GN=BG08_6022 PE=4 SV=1
EWFYTPGWMEKEIVDVTKGSTKSWLLFLDNEHIGLALKEKLERDGRVITVGVGPSYKKISLNEFTICPTEQEDYYQLFNELQKQECLPEEIVHLWNVDNK
D------LGIETLDTGFYSLISLAKTISKFLYPININVMTNNMQKVVGDESIIAEKSTLLAPIKVFPQEYPNIRCRSVDFMLSDNEE--ALISNLYFEIQ
TDIIDTVIAIRNNTRYIRIYEPIPDENELASKIPNIRSEGVYLITGGMGGVGLKLAEYLARTVKAKLILVSRTALP--DREEWDQLHEQIQKLESLGAKV
MTAVADVADEEQMRNVIHQAE-ANFGHINGVIHAAGVLRVKSMEKISRIECEEQFLPKVHGVLVLDKLLSNYDLDFCYLVSSLSPILGGLGFVAYSAANL
YLDSFSDKVSNTSNNRWTSINWGDWQYTGAQNKIFN---AQSIEALEMTSEEGQKTFQCVLGLSGL--------------------------NQVIIS--
---SGDLNKRFDQW--------------IN---LNSRKRIS-GLETQ--------TQTKTGDKFRNQDEVEEIIIGIWKEFYSVDTVNVNENFFDLGATS
LHIIQIHERLINRLEKQISIGVMFEYPSIRSLARYLSGD-----------
>tr|D3P6E4|D3P6E4_AZOS1 Polyketide synthase OS=Azospirillum sp. (strain B510) GN=AZL_d03970 PE=4 SV=1
DWLYRVSWKPSPAMEVTATAPSHWLILADDGGVGQALAARLAQGATCRLLSLDGIAAED------GMAVGAAEFAEPIDSLIRNAGGGPGVVSLWGLDAH
LDPDGDAEIEPARRRAFGNLLLLTQALARHPAVPRLWVVTRNAVSATGTEPQAVVQGGLWGFGRSVSLEAPALWGGLADLEAADADGSEVEVAALADHLL
RDDGEDQVAFRDRTRYVARFVRQPVPERTTLATAGSSVAGCWLITGGLGALGVETARWLIQRGVRDLVLASRRGADDPA--AKPVIEMLEG----LGARV
TVAKADIGRRKDVQRLLQKLG-RGSVPLRGIVHSAGVLDDATIPQMGWEKFRRATIPKLDAAWYLHRYSRDLPLDAFVVYSSILSLFGAGGQVNYTSGNG
CLDALVTHRR-RLGLPALAINWGPWAAVGLATLSQGEAIWRARGLIYIPPEVGAEALDAVVGSEIEQAATINDWT-------------------------
------AFARQFTRPPRYYEEVLPAA-------------AVAESAE---PAALPDGLT-----STE---PAQRRSALVAATLLTKPVDPTRPLRELGLDS
LMAVTLINRVEAGLSVRIPAVVLIRGPSIEELVDEVWPD-----------
>tr|M2Z4U9|M2Z4U9_9PROT Phenolpthiocerol synthesis polyketide synthase ppsA OS=Magnetospirillum sp. SO-1 GN=H261_13828 PE=4 SV=1
SGLYQLRWEEEAAPAAAGGGPAAWLLLGGDGGTGPALAAALAEGAVVRRVVSADVPA------------TPEVMGELLRSFAAPAGRRPGIVHLCGLDAA
GQAQ---TDETAQRRVLGTALALAGILALFQAGARLWLVTRNAVAASADDPAEILQAGLWGFGRSLAVEMPALWGGLIDLEAGDDGV-----APLAARLA
RPDRETQSAFRRGRHLVARLAAIAPPEP--------ESGGTYVVTGGLGAIGRRVAEWLARRKAEVLVLVGRQGGKAAD--AAAVTRAIEA----IGARV
VIVKADMGDRADVRRLMRRVG-ALGPPLRGIYHSAGLVDDGMVEGMDWAQFRRVLAPKLDGAWWLHEASRDAGPCDFVLFSSVLSLLGSAGQANYTAANA
CLDALAAHRR-SLGLPALAVNWGPWAEAGMAGGLRAQAVWQARGLSFISSETGGRAFDLLFGGGLGQVAAQVDWT-------------------------
------AFIGQFAETPPLLAHLQGKV-------------GAGPAAG---LVELRASLA-----SGS---PARRRAALTAAALLSEPIEPGRPLREVGLDS
LMAVTLTNRIEAAAGLLIPTFNLIRGPSIDQLIDELWPD-----------
>tr|Q2W5X2|Q2W5X2_MAGSA Phenolpthiocerol synthesis polyketide synthase ppsA OS=Magnetospirillum magneticum (strain AMB-1 / ATCC 700264) GN=amb1949 PE=4
GWLYVPRWDDRPVPPVKASGPLTWLLLGGDG--AKPLKEALRTGAACRLVAAKDCPT------------DLEGFSRLLEGFAAEAGAGKGILHLGAVDAP
GEEA--WGDEGAQRRLYDSVLGLSRALGGFLVAPKLHLVTRNAADATGTEPAHVLGAGMWGMGRSLALEAPALWGGLIDLEAGGASGAE--AQLLAAHLA
AADDEAQVALRGGKRLAARLVRAPVPER--------GEGGTYLVTGGLGALGVLTAEWLAARKAAHLVLVSRQGDKAAN--AAEVLARLEA----LGAKV
TIAKADIAKEGDVARLLGRLA-KAEPALKGIYHSAGVLDDGLVDQMDWTKFRRALAPKLDAGWWLHKHSQGLKLHDFVLYSSVLSVIGSAGQTNYTTGNA
CLDALAAHRR-ALGLPALSVNWGAWASAGMADGLQGEAIWRARGIHYIEPDLGREAFDLLFDGAAGQAVLPADWP-------------------------
------TFLRQFQVPPRFYAELQGGA-------------VGGLAAD---IEALKQAMA-----APE---PGIRRAAITDTTLMTAKVESDRPLRELGLDS
LMSVTLINRVESATGLRIPAVKLIKGPSIDELVADVWPD-----------
>tr|A0A0F5A735|A0A0F5A735_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. MUSC164 GN=VT50_27160 PE=4 SV=1
ESLYQVEWVPTAPDTFVASGAGRWALVGPDLGAADVTVDTH------------P------------------DLAALAVAIDAG-ATAPVVLAAQVSR--
----TRPELAEAVRAGHRALDLLKGWL-DEFGASRLVFLTRGAIAAGAD-VADPAAAAVWGLVRSAQSEHPGRFV-LADLDDHDGS--R---RILPAAL-
--ADEPQFVVRDGEVLAGRLARVPAPG-TVTSGPTWDPRGTVLVTGAASGLGGLVARHLVGHGVRHLVLVSRRGLAADG--AAELRTELAD----LGADA
TVAACDTADRDALAALLAALP--DEHPLTAVVHTAGVLDDGVVE-LTPERIDRVLRPKVDAVLNLHELTAGLDLSAFVLFSSLSGTLGGTGQANYAAANA
FLDAFAQRRR-AEGLPAQSLAWGLWEERSGMTGKAHMRRLAREGVTPMASEEALALFDTACGIDT-ATLARLNAS-------------------------
--------AWRAQDGPALLRGVIGPAKSTG-----GSGA------D---SAELRRRIG-----SMN---PAARRQALLERALHDNARMPDRGFLELGFDS
LTAVGLRNQLGTATGLRLPATLLFDYTTSRALAGYLADE-----------
>tr|W4M159|W4M159_9DELT Uncharacterized protein OS=Candidatus Entotheonella sp. TSY1 GN=ETSY1_00130 PE=4 SV=1
DWLYDITWQPMPYS-PGSVQSGSWLVLAGETGLGKTLAARLARGQRCVLVSASQADQTG-------------LADLLRGSM-GAGQPPCGVVYLWGVDTD
STPAEL---PELTHRLCVQVLDLVQAI-E--MTPQLWLVTQGAQAVGKTDRLQVQQAPLWGLGRTIAREHPELQCVCLDLPADATSEDNA--HTLFEAL-
-TDAENQIAYRQGTRYVARLVR------RSGIPLPIHETGGYLITGGLGGLGLRVAQWLVAEGARQLVLCGRQGAATPA--ARQAVEALQQ----IGAKV
VILQADVAVQNDVVRMLTAA--QELAPLRGIIHAAGVLDDGILLQQSGARFATVMTPKVAGSWHLHQLTEIIPLDFFVCFSSTASVLGAPGQGNYAAANA
FMDALAHHRR-ALGLPGLSVNWGGWSEVGLAAASN----EPSSGIGAIPPEQGVQVLGVLLRRETAQATMPVDWT-------------------------
------VLRQQFPSRDPL---LTLQQ-------------DGSEHRL---RGDELARLQ-----TAD---TVTRQQLLIAQLLAGASGGAEMSLTALGLDS
LMTIEFANRIKAELAVSVPVRKFLEGTSIAQLAQYLNTL-----------
>tr|A0A0A4GSQ2|A0A0A4GSQ2_9PSED Uncharacterized protein OS=Pseudomonas mediterranea CFBP 5447 GN=N005_01590 PE=4 SV=1
-WLTTVEWVPQPSRTPDQSPGGMWLFIGGTGELVQGIGKGLSNDGPVVHALFADDCRRVSAHLWHIRMGFPEDLHELFQSLPVSAQCPLGVVHLGGTDPI
AAQDRREQEDLAPLTGLYSVVATLQALAASSEVARFWIVTRAAVNVRSA-LISVAQAPLWGLAKVIAQEEPAAWGGFIDLPPDLEDV-LSLAAQLML---
-GQEDQFAIRQGGVHVPR---LVEASP-VKSRHVALSPQATYLVVGGFGGLGREVLAWLVEKGARHLAVIGRKSLDATGST---VLESFRH----QGVSI
DYLRLDIATGEAAETLASYIG-TLQWPLRGVLQLAGTVEDAVLSKLSASSLHHVLLPKLQGTQVLDRVTRDQPLDFFIGFSSISASLGFKGQANYVAANS
AMDAIMENRV-SSGLPGLSIAWGPWSSEGMASRVFLSALGI----NFISAQAGLQRLWDNL-SAQGVMGAPIDWK-------------------------
------PYKAHLQSSN--YLSLI---ESTAE---GDTVP-------------FLDTVS--------SLDGEQRQAFILGGGFDA--DAMDKSLTMMGFDS
LMTVEFRNSL-KKLGINFPLGRLIVGATLNDIGDFVLEH-----------
>tr|W7YD27|W7YD27_9BACL Malonyl CoA-acyl carrier protein transacylase OS=Paenibacillus pini JCM 16418 GN=JCM16418_325 PE=4 SV=1
AECYQPRWVPAPIALAEPQVTGTVLLWMDDQGIGSSLSELLSKGRHVIELFEGEQYEQISDDSYSLSLS-EEHFIQMWEDVREAG---VHFIYLGALSGP
DHAKERTE-LALQMRGVHGLFHLARSFAKWKLPLEWLVVTSGAVVVDGKEVIRPHHAAMAGLGKVLNQEFPNLQVRFMDMDEVLPEVS------IEQEL-
LEERDFHVAYRDGIRYTLEIAPLKQNL-RADHEVVVKAGGTYLITGGTGGIGLELASYLSSLAPVNLILINRSLVPERQEARITRLQAIEN----NGSQL
HCYRADVSDEAEMISVLEEVS-RDYGPIHGVIHAAGVAGDGMILRKESAVFTNVLAPKIQGAWLLDKYVNSEHLDFFVLLSSVTAITGGLGQGDYTAANS
YLDAFAHHRR-LEGKPALSINWPAWKETGMAVNY----HDAPAVWKSLATHKALQYFDLLLHSGVPQAIGELDMETT-----------------------
-----ANLIDQLPFRF----------SKVESGIITDPLQYTNQSAQ---AVLTLTGKS-----ETDISPLEQQVAQ---TVLGL--EEVYESFYDMGGDS
ILAAQLYRKLDQHFPQTVDISDIFSYPSVIEMAEYLDSL-----------
>tr|D7F198|D7F198_9CYAN Polyketide synthase OS=[Oscillatoria] sp. PCC 6506 GN=cyrC PE=4 SV=1
DWLYEVVWQPQLLPLSVATEGRQWLIFADASGYGEALAAQLQQGDITTLVYAGQEYRSANNEYFRIDPTQGEDYERLLAVL-----PRLGIVHLWSLDIP
SLDR--SDLIENVQLNTGTLLHLLQAV-E-TRTPSLWLVTNNAQAVRKDDVVGVLQSPLWGMGKVIALEHPELNCVSIDLDREGLPNEQA--KFLAAELT
AIPHESQVAWRNGTRYVARLKRY-----ATSPKMLIRPDATYLITGGLGSLGLLVARWMVEQGATHLVLIGRGQ-PQPA--AQQQLQEIAA----LGATV
TVAQADVGIRSQVADVLAQI--DKAYPLAGIVHAAGVVDDGILLQQNWARFRKVFVPKLEGAWHLHTLTKEMSLDFFVCFSSSAGLLGNAGQANYAAANA
FLDAFAHYRR-RQGLPALSINWDAWSDVGMAARLASATVGQDSSTLEIAPEQGLQLFAYLLQPS-AQIAISTDG--------------------------
-------LRTMYDT--AFFALLNQEQ-------------STPPHEV---GPTLLEQLQ-----QTR---PKEREKMLLRAVLSPELPAVHQPFTELGMDS
LMSLELRRRLEESLQIQMPATLAFDYPMVDRLAKFLLTQ-----------
>tr|B0LI39|B0LI39_9NOST Polyketide synthase OS=Cylindrospermopsis raciborskii AWT205 GN=cyrC PE=4 SV=1
DWLYEVVWQPQLLTLSVETEGRQWLIFADASGHGEALAAQLQQGDIITLVYAGLKYHSANNKYFQIDPIQREDYERLFAAL-----PPLGIVHLWSLDIL
SLDK--SNLIENVQLGSGTLLNLIQTV-E-TPTPSLWLVTKNAQAVRKNDLVGVLQSPLWGMGKVIALEHPELNCVSIDLDGEGLPDEQA--KFLAAELT
TIPHESQVAWRNRTRYVSRFKGY-----ATSSKMPIRPDATYLITGGFGGLGLLVARWMVEQGATHLFLMGRSQ-PKPA--AQKQLQEIAA----LGATV
TVVQADVGIRSQVANVLAQI--DKAYPLAGIIHTAGVLDDGILLQQNWARFSKVFAPKLEGAWHLHTLTEEMPLDFFICFSSTAGLLGSGGQANYAAANA
FLDAFAHHRR-IQGLPALSINWDAWSQVGMTVRLASTTVGQDISTLEISPEQGLQIFAYLLQPS-AQIAISTDG--------------------------
-------LRKMYDT--AFFALLDQEQ-------------STLSHEV---GLTLLEQLQ-----QAR---PKEREKMLLRAVLSPELPAVHQPFTDLGMDS
LMSLELMRRLEESLGIQMPATLAFDYPMVDRLAKFILTQ-----------
>tr|C6WPH8|C6WPH8_ACTMD Acyl transferase OS=Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971) GN=Amir_4853 PE=4 SV=1
AWSHHLAWRATPL---AAVPPQEWLVVGGTP-A-DEWRA--------------------GVR-TRLAPDPAAAL-----AALADGSPATLLVFA-DALGA
GGDDPDAEATL---RAF----DLVTAL-L-SAPPRLHLVTRRAHLLPGD-TADPGHAALWGAGRSAALEHPDLWGGLVDLDEHPRTAL-----RLLTEI-
-ADPGAQSAYRADTRHIPVLRRS--E--PATAPARA-LSGTHLIVGATGRIGPHLAAELVQRGVRHLVLVSRRGLRGPSAE------RLRL----RGVVV
LDLRLDVADPSAAAA-LSAHL-ATLPPLRGVHHAAFDESVSPIAALSAPLVRRMFRAKANVLTTLRRLAGEHRA-ELLHLSSTTGLLGSSGLAHYAAASC
FADSAASADP-TTRTV--VLG-PCADGLAGT---PHGEVVLASGLRLMPTRRAVAAAL----DAPARRSVDADWD-------------------------
------EVDRSYATALPLLAELA---APRP-----DPVQ---------------------------------HRELLREGAMGITPEAPRANLFALGVDS
LMSLSIIRTLAATTGHHIPPTVLRERPTALALADHLAEA-----------
>tr|Q091C1|Q091C1_STIAD Oxidoreductase, short chain dehydrogenase/reductase family OS=Stigmatella aurantiaca (strain DW4/3-1) GN=STIAU_0880 PE=4 SV=1
ELLFELAWREQRASQEVVSPPGHWLLFADSGSVAERLKELVQHSRTCVTVSPGAGYEKLGRDHYRLDPADPAGFDRLFQDL-SAGGVAPTVAYLWGLDER
-GAAELEELAGVTARSSAGALHLVQAM-AWAQRPALWMVTRGAVAAVPSDVGGLSQTPIWGLGRAAAIEHPELGCRLADLDGDEGAPARL--FQLMAE--
----------------------------SRSSPVRIRSDGTYLLTGGMGALGLATAEWLVEEGARQLVLVGRGE-PGEA--VKARINALTA----RGCHV
TVTRADVSRREEVQRLVEGIS-ARESQLLGIFHIAGVLDDGVFMLQSRERIAQVFVPKVLGAWNLHLATAQLPLDLFVMYSSAASLVGVAGQANYVAANS
FLDALAYHRS-RQGLPALSVNWGRWSGEGMAAKTK--GSTQGVDAGNLSPRRALQILGDLLMLDVVQMGVSFAVA-------------------------
------AVDSAL-SPGPLFSELMEQA-------------RSSSVAR---MHELLGELK-----SAD---SVRRRGLLTHPLLFAPDHEKKVSLNEMGLDS
LRAVELKNRIGRELGVDLPMARFIDGTNLEGIVEALHSQ-----------
>tr|S9NWG4|S9NWG4_9DELT Malonyl CoA-acyl carrier protein transacylase OS=Cystobacter fuscus DSM 2262 GN=D187_009448 PE=4 SV=1
ESLFELVWREQRAPWAIPTRPGRWLLLADSGGVATQLKERVQHSGTCVTVTQGAGYERIDPSHYRLDPTDAASFDRLLREV-SEGGAAPVVACLWGLDER
-GATELEGLADATARGTAGVLHLTQAM-TWAQRPVLWLATRGAVAAAPADVEGLAQVPIWGLGRAAAIEHPEFGCRLVDLDTHEDAPARL--FQLIVE--
----------------------------SRATPVRILADGTYLITGGMGALGLATAQWLVRSGARHLVLTGRGE-PGDE--AKATISALTA----SGCQV
TVARADISRPEDVQCLVEEIS-ARGPRLRGIFHSAGVLDDGVMLLQDRERFSRVFAPKALGAWNLHLATAQLPLDLFVMYSSAASLIGVAGQANYVAANG
FLDALAHHRS-RRGLPALSINWGRWAGAGMASKTR--GGISASDASSIPPQQALRILEELLAREVTQMGVPFNVS-------------------------
------ATEATA-SPGPLFSGLMEQP-------------RSVGASR---MHELLDELK-----RAD---STRRRVLLARPLLFAPEHEKEISLNEMGLDS
LRAVELKNRIGRELGVELPMARFIDGTSLDGIVEALHTQ-----------
>tr|A0A0F7BMW2|A0A0F7BMW2_MYXFU Polyketide synthase OS=Myxococcus fulvus 124B02 GN=MFUL124B02_24075 PE=4 SV=1
ELLLELAWRELEAPRAASLQSQRWLLLADSSGVADGLKVQVRRGGTCVWVTPDA---SDEPGHVHVDPNQPEGFVRLLQSL-SEEGAAPTVVCLWGLDEP
-GAEALES-----TRSATGVLHLVQAM-SWAQRPALWLVTRGAVAATPGDVDGLAQSMLWGLGRAAALEHPELGCRLVDLDEGEDAPARL--FERMTR--
----------------------------NSANPVGVHADGAYLITGGLGALGLATAAWLVDAGARHLVLVGRGA-PGEA--TKLRLDELGA----RGCEV
TVARADVSRLDDVRRVLEEVS-ASGTRLRGIFHVAGVLEDGVFLRQDRERLARVLAPKVMGAWNLHHATAGLPLDLFVMYSSAASLVGVAGQANYMAANT
FLDALAHHRR-AKGLPALSVNWGQWAGGGMAQKA----RTATSDATSLPPQRALRILEELLGRELTQVGLPVDAS-------------------------
------TQGASL-SEVPLFSELVGKE-------------PSASTGR---MVELLEEFT-----RSD---GARRRGLLTHPLLFPPEHEKKISLNELGLDS
LRAVELKNRMGRELGVDLPMARFIDGTGVAGIVEALHEQ-----------
>tr|Q1D4F1|Q1D4F1_MYXXD Polyketide synthase OS=Myxococcus xanthus (strain DK 1622) GN=MXAN_4297 PE=4 SV=1
ELLFELAWREQPAPSAVASQSGPWLLLVDSDRVADEVRTLAQRAWICVVATPGASYERVDANHYRLNPHDAAGFDRLLQDV-S----APAVAYLWGLGDR
-S----EALSGAVTSSTLGALHLVKAM-GWAQPPALWMVTESAVAATPTDVEGFAQASLWGFGRAVAIEHTEFMCRMVDLEPGSESLERL--FLLMAQ--
----------------------------ERAAPVRIRPDGVYLVTGGLGALGLETAEWLVGAGARHLLLVGRSE-PTDA--ANARLAALTA----RGVGV
TVARADVSRQEDVQRLVASVS-ERGLSLRGIIHTAGVLEDGVILHQDAERFSRVFAPKVQGALNLHRATAGMPLDLFVMYSSAASLVGVAGQSNYVAANS
VLDALAHHRN-RLGLPALSINWGRWAGAGMAAKS----RPEASDAASLSPEVALQVFEQLLEQGAVQVGVPFSVS-------------------------
------SLEAGP-SPGPLFSELMEQA-------------RSAAASR---MHELMEELK-----RAD---GERRRALLTRPLLFAPDHEKRISLNEMGLDS
LRAVELKNRIGRELGVDLLMARFIDGTTLDGIVDALSTQ-----------
>tr|F8CN02|F8CN02_MYXFH Polyketide synthase OS=Myxococcus fulvus (strain ATCC BAA-855 / HW-1) GN=LILAB_29635 PE=4 SV=1
ELLYELAWREQPAPTAVATQAGSWLLLVDSEGLAREVQALAQRSWRCVVATPGTGYACVDAGHYRLDPYDAAHFDRLLQDV-SADGAAPAVACLWGMGDR
-S----EARSGALTASTVGALHLVKAL-PWPHRPALWMVTEGAVAATPTDVEGFAQAALWGFGRAAAIEHTELACRMVDLEPGAEALERL--FHLMAQ--
----------------------------GGTAPVRIQPEGVYLVTGGLGALGLATAEWLVGAGARHLLLVGRGG-PSDA--ANKRLAALTA----RGADI
TVARADVSRLEDVQRLVAGVA-ERGQHLRGVIHTAGVLEDGVILHQDRERFSRVFAPKVRGALNLHRATVGLPLDLFVMYSSAASLVGVAGQSNYVAANS
VLDALAHHRR-HQGLPALSLNWGRWAGAGMAAKS------EASDAASLAPEVALQVLEQLLEQGAVQMGVPFSVS-------------------------
------SLESGP-SPGPLFSELMEQA-------------RSAGASR---LQELVDELK-----RAD---GERRRVLLTRPLLFAPDHEKKISLNEMGLDS
LRAVELKNRIGRELGVDLLMARFIDGTTLDGIVDALSNQ-----------
>tr|A0A0H4WWG6|A0A0H4WWG6_9DELT Malonyl CoA-acyl carrier protein transacylase OS=Myxococcus sp. (contaminant ex DSM 436) GN=A176_002592 PE=4 SV=1
ELLFELAWREHAAPAGVANHPGACLLWVDAGHDAEAVRALAERAWSCVVVTPGPAYEHVEPGLYRVDPMDPAGFERLLQDV-VAAGTVPTVAYLWGRSER
-A----ESPSGEVPWNTVGALHLVKAL-NWAQRPALWMVTEGAVAVAATDVDRFTQASLWGFGRAAAIEHTELRCRMVDLEPGDDALARL--FHLMAE--
----------------------------EQAAPVRIQPEGVYLVTGGLGALGLATAEWLAGAGAKHLLLVGRSA-PGDE--AKARLQSLSS----RGVDV
TVARADVSRWDDVQRLVDGVA-ERGSRLRGVIHTAGVLEDGVILHQDRTRFSRVFAPKVQGALNLHRATAGLSLDLFVTYSSAASLVGVAGQSNYVAANS
VLDALAHHRR-RMGLPALSINWGRWAGAGMAAKS----RGEVSDGSSLAPELALQVFEQLLEQGAVQMGVPFSVA-------------------------
------SLESGP-SPGLLFSELMEQA-------------RSAGASR---MHELMEELK-----RAD---SERRRALLTRPLLFAPDHEKKISLNEMGLDS
LRAVELKNRIGRELGVELLMARFIDGTTLDGLVDALHTQ-----------
>tr|L7UHB6|L7UHB6_MYXSD Polyketide synthase OS=Myxococcus stipitatus (strain DSM 14675 / JCM 12634 / Mx s8) GN=MYSTI_06012 PE=4 SV=1
ELLFELAWREQA-ARTLPLLSGRWWVLADAGGAAHALKEQVRHGGSCEVVTPGPGYERSEPGLTRLDPSAPEGFTRLLTEL-SSEGAAPTVVCLWGLDEP
-EAEALESLAGATSRSAAGVLHLVQAM-SWAQKPVLWLVTRGAIHAAPGDVTGLAQSTLWGLCRAAAIEHPELSCRMVDLDDSEDAATRW--FERLTV--
----------------------------NRASPVSIQADGAYLVTGGLGALGLATAAWLVEAGARQLVLMGRGA-PGDE--AQARLEALRA----RGCEV
FVARGDVSRLEDVRRVVEEVS-ARGSTLRGLFHTAGVLEDGVFLRQDRERLARVFAPKVLGAWNLHQATEGLPLDLFVMYSSAASLVGVAGQANYVAANT
FLDALAHHRR-AKGLPALSINWGRWSGGGMAEKG----PGRAPDATSLSPQRALRVLEELLGRDLAQVGVPVNLS-------------------------
------SVEATP-SAGPLFSELAEQA-------------RSVTTVR---LVELLEEFK-----RSD---GTRRRGLLKHALLFPPEHERTISLNEMGLDS
LRAVELKNRMGRELGVDLPLARFIDGSGLAGIVEVMHEQ-----------
>tr|I0J6Y8|I0J6Y8_SORCE Polyketide synthase OS=Sorangium cellulosum GN=pelB PE=4 SV=1
GCVHEVVWRRAERLP-SLGATGAWVVFSDR-GVGAGLHGRLGAGQRCVRVFAGEGYEQIEPDLYRIDPGKRDDYARLLREAFGEEGS-CGVVHLFSLDAA
PIEAATEALAAELAGGSVSAAYLTQAL-HGRDAPRLFLVTRGAQGVHEH-AVSVGQAPVWGLGRTIALEHPEVQCTRIDLAPGASEADA---ARLAREL-
----EDQVALRGD---------------S-ARRFSLRPDASYLITGGLGGLGLSLARWLVEQGARHVALVGRRGAGPEA---QQAIREMEE----AGARV
LVEPADVSCRDEVERLFARVE-EKLPPLCGIVHAAAVLDDHTLLEQSEESFRKVFGPKALGAWHLHALSEGRALDFFVMYSSGASLFGSPGQGNYAAASA
FVDALSRERA-RRGLASMSIQWGAFAEVGLAAAQNRGKRLSSRGVASFTPAEGLEALRRLLLNPRAEVGVRFDAR-------------------------
------QWSEFYPVAAPLFAELTD-REAP--------RV------R--------QALE-----EAA---PHERLPLLERAVLRLDPRRRGAPFQSLGMDS
LMSLELRNRFEASLGIRLSAILLFTYPNVSALSRHLLAM-----------
>tr|D6U8P2|D6U8P2_9CHLR Acyl transferase OS=Ktedonobacter racemifer DSM 44963 GN=Krac_0080 PE=4 SV=1
QLLYSIQWEQQVSTE-VQESRKRWLIFGAH-GPAQKLVEYLANGAECIVVTPGNTYKQVQVQHYELNPTSPEEFHHLFSELYQGGQT-IGIVYLWSLLTQ
PVNEASHALFEDQELVSIGTLHLLQAL-TKETTPRLYLVTSGVHAIEEQ-TTALSQAPLWGLGRVIVYEHQDLHATLIDLDPTPSEESI---KALCKEI-
----ADEVALRGK---------------QESSETLFRQDGTYLITGGLGGVGLRTAQWMIEQGARSLVLMGRRGPSEEA---QATLHMMRD----TGATV
HLMLADVSQEEQLALALDEIR-RRMPPLRGIFHSAVVLDDSTLLQLDRERFQGVMPPKVDGAWNLHRLTLNDPLDYFVLFSSAASLIGSPGQGNYAAANA
FMDMLAFYRR-QQGLPALCINWGRWGEVGQAM-KDRGERLDVRGFASMKPKEGLAILGELLRQSPPQVGMSFHLP-------------------------
------KWSQFYPNLTSLFADLVAGAAEP--------RL------T-------GDMLV-----TLD---EEARHQALSQSVLGHASLNAYQPLNRLGIDS
LMSVELRNRIRADLDVTIAVTTFLKGVTFEQLIGEILEG-----------
>tr|D2AZU2|D2AZU2_STRRD 6-deoxyerythronolide-B synthase OS=Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100) GN=Sros_4286 P
RLLYGVEWAELEPLT-VP-ERAPWLVVSDS--LGAELCASLAAGGEPLLVQPGAGYRRLGPHRCVLDLASTEDWTMLIKEQSESGAW-PRAVVRL-STAP
PVEEATDALERS-----YEVLALVKGL-SDQAAPRLWLVTTAAQTPDGS-DVNPAETAVWGIGRVIPYEHPELRCSMIDLPEDPDSGIL---RALSAEI-
----ETEIALRDG---------------S---PVPVRPDGTYLITGGCGGVGLLTAEWLVKNGARHLVLVGRGGAPEGV---TDRIAAMRS----AGAQV
LIARTDIASRVAVADLLDDIA-RHMPSLRGVVNSAVVLDDGTLAQLDRARFLAPMPPKVHGSWHLHELTRHLPLDFFLLYSSAASVIGSPGQGNYSAANG
YQDGLAWHRR-ANGLPALTVNWGQWSATGQVA-KSKDLRLNERGFAGFAPAEGLAVLDRLLPSLHAQASMSFDPT-------------------------
------AWTHYFPALRSLLRHLVP--AA---------EL------E-------PADLA-----GLG---NEQAEQLIAAAIVQLPRAKAAQRPHRMGLDS
LMAVQLRNRIAADLGVTLPVAVFLQRRTIGDLATVTLTH-----------
>tr|A0A0C2PTN1|A0A0C2PTN1_9CYAN Uncharacterized protein OS=Tolypothrix campylonemoides VB511288 GN=SD81_24665 PE=4 SV=1
DWFYEVEWRPQARLEIETSAAKNWLIFTDNLGVGQQLAAQLTLGDICTVVTAGQQYQQLSPTHFTINPEQKEDYSLLLEQI-AISTPDIGVVHCFALQGA
QTSTLTTALEAESQLGCKTTLMLVQAL-KSLHKPRLWLVTRGAQLLAPDHMSAIAQSSLWGMKKAIALEHPEFRCTCIDLDASATISEQA--HALLAEV-
-FDLEDQVLLRKDTRYVARLVRSRSLSRESGTGLSCHPEGTYLITGGLGALGLLVARWLVERGARNLVLLTRSR-PNPQ--AQTQLQSLEQ----TGVRV
EFVQADVSNYDSLAQAFSHIQ-QSLPPMRGIIHSAGVLDDATVLQQNWEKFATAMAPKVQGAWHLHQLTQTQPLDFFVLFSSAASLLGSPGQANYSAANA
FLDALAHYRS-SLGLVGQSIHWGAVSQVGMAARRD--VLVQKYGMGVISPPQVLEALSLVLHPTVVEVGVPIQWS-------------------------
------QGLQ------ANWSFLAQQI-------------LTATSAT---ESEFLQQLK-----AAT---PNRQRNMLMSKILIKQAYSPRQRLFDLGIDS
LMAVELKNLLESQLNCSLSSTLVFDYPTPQVLVDYLMSQ-----------
>tr|D0LS56|D0LS56_HALO1 Acyl transferase OS=Haliangium ochraceum (strain DSM 14365 / JCM 11303 / SMP-2) GN=Hoch_1186 PE=4 SV=1
GWLYENAWREAPRQA-EAGAEGTWLVVTEHEGLGEALCAALKRGGSCIVASMGASFADRGGDNFELDPEVAGDWSQWLSAARAAAASDIGVVYLPAATAL
A-GEPLETALAAQRLVTVAPLLLTQAL-AGRDPPRLLLITRNVWAGDDA-PSACAQAPLWGLGSTVDFEHPELRCTRIDLGAQSAADAA---EDIVSEIV
SSHDERAIKLHGDERQVLRLTQVRPDEPSVLETGQMDSEKSYLITGGCGGLGLSVARAMVQRGARHLMLLGRSGGNDAS---ARAVAEMEA----EGAEL
RVVAADVADEARMGEVIAELR-ETMPPLGGIIHAAGILDDAVITHLDVARLHRVMAPKMLGAVNLDRLTRDCELDFFVLFSSATTLIGSPGQANYCAANT
FLDAFAHHLR-ARGRRALSINWGAWTEVGLAAAQNRGARLEHRGLGAMNPEQGAEAFLSVLSSAHAQIGMSLDVR-------------------------
------QWQQYYPKAAPLFSELGAKGEN---------EF--------------VSALR-----AAP---AAQRAMLMEEEVLRIPADRADASFRGLGLDS
LMAIEFRNRLESISGLTLSATMVWSYPTPRALAAELLRR-----------
>tr|J9Q2B8|J9Q2B8_STRPT PKS OS=Streptomyces platensis PE=4 SV=1
TSLYTVEWPVKELPE-EGSAARAWAVIGAPEGVE---LSHY------------A------------------SPATLAAALDATDVPVPAVLVPCFSPHS
PGCPPGAGLVERAHYAATVLDLVRTWL-DAFEASRLLLLTRGAVTPDAGHLSDELGSLAWGLVRTVQNEHPGRVL-VADLDEDPAS--W---SVLPGVL-
--HEEPQVAVRRGVAHVPRLTAAR----AAERATPFDSVGTVLVTGGTGGLGSLLARHLVVHGVRHLLLTSRRGPQAPG--AAALAAELTE----LGAQV
TVTACDMADSPAVEELLGSLP--AGHPLTAVIHTAGVLDDGLVQ-LTPERLNTVLRPKADAAVVLDRLTRHLDLAAFVLYSSVGGTLGGPGQGNYAAANA
FLDALAQRRR-AEGLPGLSLGWGLWSDTTGMAAETHVGRLNRSGLVTMSPAEGLALFDAAISGGYGPVVVRLDLP-------------------------
------ALKARATSGASVLADLVGPARAAK-----SGTV------S---GAALRAALS-----QLS---EDERRRMLLDAVLLRQDGAEEQPFKDLGLDS
LTAVELRNRLASATGLQLPATLLFDLPSPSALAHHLLTR-----------
>tr|A0A0E9AG82|A0A0E9AG82_MYCTX Phenolpthiocerol synthesis type-I polyketide synthase PPSA OS=Mycobacterium tuberculosis GN=ppsA PE=4 SV=1
NFVHTIDWQPQTVP--ATHPGAEQVTHPGPV-IGDDGAALC------------------TLEGAGYQPA-----------VMSDGVSQAYVVYVADSDPA
GAD--EVDFAV---RICTEITGLVRTL-RDDKPAALWILTRGVHE--SV-PSALRQSFLWGLAGVIAAEHPELWGGLVDLAINDDLGEFG--PA-LAEL-
-KPSKSILVRRDGVVLAPALAPVRGE--PARKSLQCRPDAAYLITGGLGALGLLMADWLADRGAHRLVLTGRTPLPPRRDRRIDAIRALEM----RGVTV
EAVAADVGCREDVQALAARDR-DGAAPIRGIIHAAGITNDQLVTSMTGDAVRQVMWPKIGGSQVLHDAFPPGSVDFFYLTASAAGIFGIPGQGSYAAANS
YLDALARARR-QQGCHTMSLDWVAWRGLGLAA--AQ-LVSE--ELARM------GSRDIT--P------AFTAWE-------------------------
------FVDG-YDVAQVVPMPAP---AG---------ADG-SGANA---YLLPARNWS-----VMA---ATEVRSELEQAELRVPEKETDRPFAELGLNS
LMAMAIRREAEQFVGIELSATMLFNHPTVKSLASYLAKR-----------
>tr|G9NQL7|G9NQL7_HYPAI 6-methylsalicylic acid synthase OS=Hypocrea atroviridis (strain ATCC 20476 / IMI 206040) GN=TRIATDRAFT_45540 PE=4 SV=1
SLVHQLVWVPPAFKEQR--DLTHVIMVSSDL-LLEAYSTQL---NKVTRVTCRNRV---------------VELSDLSAAL----SEKGIVVYAPPAIES
AAQVADEE-------FIWQTASIVKALAIGSVLAKFFVLTNRVFSGE---VTSLAHGALYGLARIIASEHPDIWGGLIDSESSSDFPMLA--IRYVD---
---DYDILRINDGLPRRAIMRR------GIANTLMPKPEGTYIVTGGLGDFGLETCNFLIEKGARNVVIVSRRGLPLPNYAVINRIRAFEA----QGATI
HTLALDITLPDAADLLKAIRA-LNIPPVLGVVHAAGVLEDSSLVETTRDSFARVLAPKVNGALALHSAFPPGSLDFFIMYSSIGQLVGTVGQASYGSSNA
FLDALATHRR-AQGDNTVAFQFTAVRGLGMATGTLLMTELRSKGITDITAGEAFR-----------------AWE-------------------------
------HLGRYDVESATRCLPLL---LLEDIVVTAANSM-ATVTTN---NDTIDDGTV-----PAH---PLDREKWVDKRVLMMDDIDLQTRLSDLGLDS
VMTVALRQAFQAVFKIKVPLTLTWSHPTLKHLVPWFLSR-----------
>tr|X7Y6L2|X7Y6L2_MYCKA Phthiocerol/phenolphthiocerol synthesis polyketide synthase type I PpsA OS=Mycobacterium kansasii 824 GN=I547_0279 PE=4 SV=1
SFVHTIDWQPRVDVV-QAHPAPGRLTGPQPV-IGDDGAPLR------------------HLENAGYPPA-----------A----VSDAYLLYVADSQPA
TAE--EVDFCV---RVTAEIGSLVRTL-EGERSAALWIVTRGVHE--SV-PSALRQSFLWGLAGVIAAEHPELWGGLVDLPAGADLAESA--PI-LAEL-
-APSKSILVARDGVVLTPALAPVRGT--PVRQPLQCRPDAAYLITGGMGALGLLMADWLADRGARRLVLTGRTPLPPRRDKKIGAIRALEM----RGVTV
EAVAVDVGCREDVQALTKRDR-DGAAPIRGIIHAAGVTNDQLVTQLTEDAVRQVVWPKVAGSQVLNEAFPAGSVDFFFLTASAAGIFGIPGQGSYAAANA
YLDALARARR-QQGCHTMSLDWVAWRGLGFAA--AQ-IVSE--ELKRM------GSRDIT--A------AFTAWE-------------------------
------YADG-YDVAQVVPVPST---AA---------VPGAVGAAA---HLKPAQDWS-----QMP---ATAVRTELEKAELRLPETDTDRPFAELGLNS
LMAMAIRREAEQFVGIELSATMLFNHPTVATLARYLTNR-----------
>tr|A0A0Q2R652|A0A0Q2R652_MYCGO Polyketide synthase OS=Mycobacterium gordonae GN=AO501_17225 PE=4 SV=1
TFAHTLDWQPRVDPT---------ALGPGNL-LGDAGA-IR------------------GLAQYGFGPG-----------G----VADAYVLYVAESQTD
-AA--EVDFAV---RVCAEVSAAVRTL-R-TDPVTLWIVTRGVYE--SA-PSALRQSFLWGLAGVIAAEHPELWGGLVDLAEAAVP--DD--SA-LADL-
-RPSKSVLVLRDNTVLAPALAALRGE--PVRKPVRCRPDAAYLITGGMGALGLLMAGWLADRGARRLVLTGRTPLPPRRDHKIDAIRALEM----RGVAI
EAVTLDIGCGDQLRALQRRDT-DGAAPIRGIIHAAGVTNDQLVTTMTGDAVREVAWSKIGGSQVLHHAFPPGSVDFFFLTSSAATIFGIPGQGSYAAANA
YLDALARSRH-QQGCHTVSLDWVAWRGLGFAA--AR-IVSD--ELARL------GSRDIT--P------AFTAWE-------------------------
------HIDG-YDVAQVLPVPST---S-----------DGSAIQDS---YLIPARDWS-----GLS---APEIRHQFESRELRLPESDSDRPFAELGLNS
LMAMAIRREAEQLVGIELSATMLFNHPTVAALANYLANR-----------
>tr|A0A0C1XZX4|A0A0C1XZX4_9CYAN Polyketide synthase OS=Hassallia byssoidea VB512170 GN=PI95_00105 PE=4 SV=1
DWFYIPSWKRSMPPQSKN-QPEYWLIFVDECGLSEKMVQQLLAGQDVITVKIGEQFERESECRYTIHPQQQDDYDTLFKELRQLNKIPDKIVHLWSVTPD
IEAE--IELQEKIELGFYSLLFLAQAIGHN-TDSQVTVISNNMQAVTGT-VLCPEKALVLGPCQVIPLEYPNISCRSIDIVVPKSESSQQLIDQLLAEL-
-QTCNQVIAYRGLHRWVQDFEPVRLDA-TVAENPRLRERGVYLITGGLGGVGLTLAEYLAQSIQAKLVLLGRSPFPEPDESKIRKLQSIEA----LGSEV
MVIGADVANSEQMSVAIAKVN-QRFGQINGVIHAAAVFGGGMIQLKTKEDAANAIAPKVRGTRVLEALFKQTKLDFFVLCSSLSSFAGASGMVDYTAENA
FLDFFAHYSA-SKYGFIKSINWDRWNSLGMAVPVH---ITGEELTGGMTTFEGI--------------------E-------------------------
------AFRRILCSSTQVFSSLIL--EEKLAQLPTHSRP-------------NLANAY-----VAPGNEVERSLAEIWQQLLGI--EQIHDNFFELGGDS
LFATQLVSQLCKTFQIELSYKGFFNGPTVAELA-IIVQK-----------
>tr|M4TB58|M4TB58_9NOSO Polyketide synthase OS=Nostoc sp. 'Peltigera membranacea cyanobiont' PE=4 SV=1
DWFYLPTWKQAKLLEPTK-QKQCWLVFLDSCQLGSQIAQQLQQGQEVITVTVGEEFSQLSDRTYAINPQCRHNYDALFQALRAIEKIPQTIAHFWGITAN
IESEIS----FGQHIGFYSLLYIAQALSQNTTSVEIMVVTNNLYDAIGQ-KLIPEKGTILGTCKVIPQEYPNLTCRNIDVIIPESGNFNQIIEQLMVEF-
-QSNDLVVAYRSSHRWIQIFESTQIPE-VVEETTRLKTGGIYLIAGDAGNLGLTFTEYLAQTVQAKLILIGNIGLPQRNENYIKKILALEE----LGTEL
LIIEADVANVEQMQAAIHQSY-DYFNQINGVFYVTPM-GNKSTQEISQTETESLFHSKVDALYVIEKVLQGKELDFCLVQSSLSSVVGGLGLVAYSAANL
FTDAFVNKLN-QISSPWFSVNWDAVKYEEKPE---NIAFGADLNELVMTPKEAW--------------------D-------------------------
------VSLRVLSMGSQFLQIRLLKHPDNSQDISQHSRP-------------NLQTPY-----IASSNEIEQKIVSIWQELLGI--EKVNDNFFELGGHS
LLAVQVTSRLREIFQVELPLQSILFDAPVAGLA-LIATT-----------
>tr|K9U384|K9U384_9CYAN Beta-ketoacyl synthase OS=Chroococcidiopsis thermalis PCC 7203 GN=Chro_3663 PE=4 SV=1
DWFYIPSWKRSLPPEPAG---KCWLVFVDECGLGERIVKRLLEGREAIAVLVGEEFRRISDRVCTINPATRADYQALLAELGDRDRQPQVIAHLWNITPS
DRPL------EKAQFSYDSLVYLAQALGREKHSVQIQVVSNNLQGVWGS-LLYPEKATILGLCRVIPQEYAQIACRSIDIVLPEAGK-EKLTEQLIAEF-
-NSSDIAIAYRETHRWVEAFEPVKLES-TVAKKTRLQQGGVYLLTGGLGGMSLVIAEYLAKTVQPKLVLLGRSVFPHRDECKIRRLQAIEN----LGAEV
LVLSADVANLAQMQDAIASST-ERFGQIQGVFHTAGVYGGGLIQLKTPETADGNLVPKVQGTKVLDLVLKDTHLDFFILFSSIASIRGQVGYADYCAANS
FLDAFAHYKS-LRDNFTASINWENWQSVGMSIAVQ---LTGKEWQQGMTSSEGL--------------------D-------------------------
------ALSRILGC-QQALQTQIPP-LQTVADCKFHPRP-------------TLSNTY-----VSPRDEIEQAIADIWQETLGI--DSIYDDFFELGGDS
LVALPMVAQLRDTFQVELPLPTLFNKANVAALA-VIIDN-----------
>tr|A0A0C1X6N6|A0A0C1X6N6_9CYAN Uncharacterized protein OS=Hassallia byssoidea VB512170 GN=PI95_57870 PE=4 SV=1
DWFYVPRWKESTPPELAG-QKLCWLVFVDAYGIGDEIAKRLQQGQDAIAVTMGQQFTKLNDRTYAINPQQPDDYNALFQALQKQDLNPNAIAHFWSVTPN
DTLLNNHQLFEDFQLGFRSLLFLAQAVGENTDPIKLMVVTSNIYDVTGE-RLCPEKATVLGPCKVIPQEYPNLTCCCIDVVIPYSE-TQQLVDNLLTEF-
-QTSENIVAYRGHHRWVQTFEKIHLDD-NIAGKTRLKQEGVYLITGGLGGIGLVLAEYLAKTVQAKLILIGRKELPERSHRKLQKVLALEE----LGAQV
QLKSADVANPEQMQAVIAQAL-KQFGQINGVIHAAGIAGGGVVQLKTPDTATSVLAPKVNGTLVLEEALKNINLDFFVLCSSITSILGDFGQVDYCAANA
FLDAYAQRH--ATTGFTVSINWDAWQEVGMAVETDIKQGREESLKKGILSQEGV--------------------E-------------------------
------AFGRILRI-KQILQSVIRGKELALLSEPTYPRP-------------NLGNNY-----VAARNEVEQIVAEIWQQVLGI--EKIHDNFFDLGGNS
LISIQVISQMQKELNIQIPLVSLYKSPTVSSLA-ILSGD-----------
>tr|S0FN33|S0FN33_9FIRM Polyketide synthase like protein OS=[Clostridium] termitidis CT1112 GN=CTER_0311 PE=4 SV=1
EWLYVPSWKSSFVTDKKN-RTGRWLIFVDEYGIGARMTDILANGCEVVTVTAGDEFVQTSRDTFKMNFESSEDYKTLFSTLKSREELPGEILHLWSMDES
RKAG--YTFFEEAQKGFYSMLYLVQALDLDSQPVKIAAVSNSSFNIGGG-TYCPERYTLAELCKIISQEFANISCRFIDVEVMTSQP-AELAKKLIGEI-
-VDEKREIAYCRNKRWVRDFERIRAEE-I-GESEPVKEKGVYIITGGTSNMGFEFLKYISKRTKGKIIILEELPFPHEREQRIRELQKLKH----EGPDI
RIVPADFTDQEKIIKLVS-EV-KGLGSINGVIHAAEVEENEIFSETDKKKCEKHFKYKAKALYLLDNALKGSNPDFAIAVSSLATIMGGLGYAAYASSNA
FIDAYANKNA-GDGNHWTSINLDAWKAAGRQDLV--TDFSTSLSRLAMTSEELE--------------------K-------------------------
------VIGMVLSLSEQILSERISGDEQEKDSGKLHTRP-------------NLQTPY-----AAPENDLEKTIAEVWAKAFGF--DKVFDNFFDLGGDS
LVAIHVVNQIKKLLKREIPAVSLYQTLNIRGMA-LLQQD-----------
>tr|A0A0C1XXB7|A0A0C1XXB7_9CYAN Polyketide synthase OS=Hassallia byssoidea VB512170 GN=PI95_00115 PE=4 SV=1
DWFYIPVWKQSQPLEPAK-QKSCWLVFVDRCDVGSLIVKRLQQGQDVITVTVGEQFTKLGDRAYCINPQQKDDYDALFQAVGQRDLTPQKIVHLWGIIAS
DRTP--IESFETSQLGFYSLLFLAQALGQGTDALQIQVVTNNIHDVTGD-SLCPEKATVLGPCKVIGQEYPNIACRNIDIVIPKSGTGKKLIEQLIAEF-
-QPTDLVIAYRGHHRWVQTFEAVRLEE-ASPEKTRLRQKGVYLITGGLGGIGLILAEYLAQTVQPKLILISRSGLPEKDERKIKKVQALEQ----LGAEV
LVKSADVADLEQMERAIALVT-DRFGEIHGVIHAAGIVGEKSQQETYITDCQCQFQPKAHGLFVLEKVLQGKALDFCLLLSSLASILGGLGYVAYSAANI
FMDAFVHKQS-QTNPPWISVNWDVWQLREQEEQ--NITYKTTLAGLAIIPTEGV--------------------K-------------------------
------AFQRILSKSRQVLQARILR-DIEQNYSPIHPRP-------------NLANDY-----VAPRTHVEQTVANIWQQLLGI--EQIHDNFFELGGHS
LLATQVISQLRKSFPIELPLRSLFSEYSIAELA-LIEQM-----------
>tr|G6FSF1|G6FSF1_9CYAN 6-deoxyerythronolide-B synthase OS=Fischerella sp. JSC-11 GN=FJSC11DRAFT_1698 PE=4 SV=1
DWFYVPAWKRVMLLEPNP-HKSCWLIFVDPCGVGSQIAKRLQAGQDVIIVTIGEEFTKLSDCIYTINPQQQDDYTTLMQTLRELGKTPQNIAHFWGVTAN
TTSLGKVEDFCKSQLVFYSLLFLAQQLTHHTTPVQIIAITNNMHEVVGQ-QLQPEKATVLGPCKAIAQEYPHMSCRSVDIVIPESETFKQLIDQLMAEL-
-QPSDLVVAYRNGHRWVQTFEPIQLNE-VVPEKTRLREGGIYLIVGDVKGLGLVFAEYLAQTVHAKLILIENSELPARNEDQIRRIQALEE----LSGDV
LIIKADVVNEEQMQQAMTIAY-ERFGQIHGVFYVPEISGNKSTHEIGKTECEQEFKSKVHGIFVLEKVLQDKKLDFYLLQSSLSSILGGLGLVAYSAAYL
FMDAFVHQKK-QQNSPWFSVNRQAFISDLEKE---YVSLGSTATELFMTPKEVW--------------------E-------------------------
------AFQRILSMGSQILQARILETVSNSKNSSQHSRP-------------NLQTVY-----VAPRNEIEQTIANIWQEILGV--SLVNDDFFELGGHS
LLAVQVTSRLRETFQVDLPLNSILFEASVAGLA-VIAQQ-----------
>tr|A0A0D6KJI3|A0A0D6KJI3_9CYAN Beta-ketoacyl synthase protein OS=Tolypothrix sp. PCC 7601 GN=FDUTEX481_09444 PE=4 SV=1
DWFYLPTWKRASLPQQTT-QPKCYLVFIDECGLGEKIVTRLLEGGEVITVKVANEYSCQSDRSYTINPEQPQDYKFLCQELRNLGKTPSHIIHLWSVTPD
NLEE-----PQQYELGFYSLVFLAQAIAFYKDNLHIQVISNHLQMVTGS-QLCPEKALIMGPCKVIPQEYVNLTCNSIDLVLPTTDSWQQLINQLLTEI-
-QTPEQVIAYRGNHRWVQDFEAIKLDT-SIQGNQRLRQNGVYLITGGLGGVGLVLAEYLAKTVQAKLILVGRSPFPQPNEQKIRKLQNLQA----FGAEI
MVISADVANYEQMSAVVKKLN-LQFGQINGVIHAAAVFGGGMIQLKTKKIADEALAPKVQGTRVLNEIFQNTRLDFFVLCSSLSAFVGTSGLVDYIAENS
FLDAFAHYHA-AQHSFITSINWDRWNSLGMAVAVH---ITKGELTAGMTAEEGI--------------------E-------------------------
------AFNKILAHSNQILYSQLL--EEQLAQLAIHPRP-------------NLDNAY-----VPPSNELEITLADIWQKLLGI--DSIHDNFFELGGDS
LFATQLVSQLCKTFQVELSYKGFFNFPTVVELA-TIAKN-----------
>tr|A0A0C1Y9I9|A0A0C1Y9I9_9CYAN Uncharacterized protein OS=Hassallia byssoidea VB512170 GN=PI95_00120 PE=4 SV=1
NWFYIPSWKRSPLP--NR-VLSCTLVFIDECGLGEELVKRLLEDQDAIAVRIGSEFTKLSDRLYTLNPRQRDHYETLLNQLLAQNKFPKTIVHLWSVTPF
DRIE--LETVDKSQTGFYSLLFLAQALGHNTDELQIAVISNNMQEVAGE-LLCPEKATLLGPIRVIPQEYPNINCRSIDVVIPKSANWQKLIDQLLCEL-
-HTSDRVIAYRGFHRWVQNFEPVRLDE-AKKETPKLRERGVYLIAGGLGGIGLVLAQHLALKVRAKLILTGRSAFPAPDECKIRKVQELEE----LGAEV
LVINADVTNSEQMQQAIAQAQ-KQFGQLNGVIHAAGVPGGGVIQRKTPEMAESILAPKVKGTLILDSILKDVQLDFFVLCSARTGILGGFGQVDYVGANA
FLDAFAHHKT-HQNGFTVSIDWCAWQEVGMAAEARSDISQTSQLKQELLPLEGI--------------------E-------------------------
------VFRRILGS-TQVLQSRDIEGKQDNGFKPTQQRP-------------SLINPY-----VAPKNETEQTLADIWQELLGI--EAIHDNFFELGGDS
LLIVQVRSKLREKLNKDISISDSFEY-SINALA-YLTRK-----------
>tr|A0A0D6YIA8|A0A0D6YIA8_MASLA Non-ribosomal peptide synthase (Fragment) OS=Mastigocladus laminosus UU774 GN=SP67_11340 PE=4 SV=1
DWFYIPIWKQSTPLEFVTKKNSRWLVFVDDYGVGDAVAKRLQQSQDIVTVRVAEKFTQLNKYTYTINPQQKNDYDTLLQELYKQSLIPNAIAHFWSITPN
DILLCNAQSFENCQLGFWSLLYLIQAFGQNSDFLKLRVVTNNVHNVIGD-KLCPEKATILGPCKIIPKEYPNVNSCLIDVVIPSTNITEKLIDYLITEL-
-QETENIVAYRGHHRWIQSFESIRLDK-NILGKTNLKKGGIYLITGGLGGIGLVLAEHLVKTVQAKLILIGRKGLPERSHRKINKILEFTE----LGSEV
EVKSADVASYEEMQLVVTEAL-EKFGQINGIIHAAGIAGGGIIQLKTEDIVNSVFTPKIQGTLVLKEILKNINLDFLVLCSSQSSILSEFGQVDYCAANA
FLDVYADYCT-SKSDFTVAINWGSWQEVGMAVETELKLQREQELKKGILSEEGA--------------------E-------------------------
------AFNRILLS-SHVFQAVILEQELALISQSSHPRP-------------NLANAY-----VAPSNEVEQALADIWQQFLGI--EKIHDNFFELAGDS
ILAIQIVAKAN-TLGIKLTSQQMFMHQTIAELVTVIETN-----------
>tr|A0A0N7AYN3|A0A0N7AYN3_9DELT Polyketide synthase OS=Myxococcus virescens GN=benC PE=4 SV=1
GWLYVPTWRRALPLPS---MRQRWLVLADTQGLGSELTEVLGLGQLVYEVRAGPRNEAISPYTFQLDPSSTDGFKALSEWLE---QPVDHLFHLWPFDLG
EGVT-----HERRLLGLESVFGLVQALGKWTAPTALRVVAPHAFDVTGG-APIPEAAALAGPCKVISLEYPTWTSQLVDLEPS-TDRGAQAARWLVREA-
-ASGDDVVAYRSGVRWLRAYEPLPSTH-LDAAEQGFREHGTYVITGGLGGVGLALAERLARHFRARLVLLGRTGLSAPHASLAERIRGMEA----AGAEV
LVIAADVAEPSSLRTALQQAQ-ERFGSIQGVLHAAAVLRDGPIQLKHMEAMHEVLRPKLDGARTLLTAASDFKMEFVILFSSLAAVLGNVGQADYAAANA
ALDALAHGHV-QDRPRVLSINWDAWLEVGAAHALAARGPLAWLLDEGLTVEEGW--------------------E-------------------------
------VLQMALRAGPQLLGRLA---EEAHEKRPEVSRE-------------RLTTRH-----VAPRNDTERLIAQAWTRHLGL--RGVYDRFVDLGGHS
LIAIRVLAELKNHFGVDLPLGAIFRAPTIAELAEQALLD-----------
>tr|A0A0C1UIN1|A0A0C1UIN1_9CYAN Polyketide synthase OS=Hassallia byssoidea VB512170 GN=PI95_00065 PE=4 SV=1
DWFYLPFWKQSVPPRLAE-QKSCTLVFIDECGLGSQLVKKLQQGQDAIAIQIGSKFSKLSDRLYTLNPRQSNDYDALLNELVAQNKIPKTIVHLWSVTPD
DCAE--IECFDSAQLGFYSLLFLTQALGQNTDEFQITVVSNNIQSVTAE-MLCPEKATVLGLVKVIPQEYSNISCRSIDIALPRQGSWEKLVDYLLDEL-
-KSSELVIAYRGLNRWVQTFEPVRLSE-ANGKTSRLRNGGVYLITEGLGNIGLILAEYLAQ-MQAKLVLIGHNSFPEKDERKIRKVQALEE----LGAEV
LVLSADVTNFEQMQSAIAFVT-NHFGNIHGIIYAAEIVGDNSQQEIYQTDYQCQFKSRANGLFVLEKVLQGRELDFYLLISSLSSILGGLGYAAYSAANI
FMDSFAHKQN-QTNPPWISVNCDRWQLGE--EQ--NTANRTTLAELFITPEEGI--------------------K-------------------------
------AFQRILTSDKQVLQARFLLGDIEQTSFIFHPRP-------------NLGNDC-----VAPRTHVEQTLADIWREILCI--EQIHDDFFELGGHS
LLAVHLMAKIKKQLGQNIQLSALFQGATIKHLA-ILHEQ-----------
>tr|B2J0Y5|B2J0Y5_NOSP7 Beta-ketoacyl synthase OS=Nostoc punctiforme (strain ATCC 29133 / PCC 73102) GN=Npun_R3425 PE=4 SV=1
DWFYLPLWKQSAPPELAE-QKFCTLVFTDECGLGSQMVKRLQQGQDAIAIQIGSEFSKVSECLYTLNPRQSNDYDALLNELLVQNKIPKTIIHLWSVTPD
YHAE--LEWFDSAQLGFYSLLFLTQALGQNTDKFKITVVSNNIQSVTAE-MLCPEKATVLGPVKVIPQEYSNISCRSIDIALPKPGSWEKLVDYLLDEL-
-KSSKLVIAYRGLNRWVQTFEPVRLSE-SKGKTSRLRNGGVYLITEGLGNIGPILAESLAQTVQAKLVLIGQKNLPEKDECKIRKLQALEE----LGAEV
LVLSADVTNLEQMQRAIAFVT-EHFGDIHGVIYAVEIVDDKSLQETSQTDYQCHFQSKANGLFVLEKVLQGRQLDFYLLISSSSSILGGLRSVAYSAANI
FMDIFAQKQN-QINPPWISVNCERWELGE--EK--NTASRTTLAELFITPEEGI--------------------K-------------------------
------AFQRILTSDKQVLQARFL-SDVEQTSFILHPRP-------------NLGNDY-----VAPRTHTEQTLANIWQEILCI--ESINDDFFELGGHS
LLAVHLIAKINNQFGKNIQLSAIFQSPTIKQLA-ILHDR-----------
>tr|A0A0F7BMR9|A0A0F7BMR9_MYXFU Polyketide synthase OS=Myxococcus fulvus 124B02 GN=MFUL124B02_23210 PE=4 SV=1
DWFYVPSWKRGPRHEPALGDAGHWLLFVDELGVGDALAE--RLGNAVITVRSGTRFHQDGPNRFTIDPRAPADYDALLGALQVQGITPSRMVHLWSVTTS
EHAT--LEAVERARLGLDSLLLLAKTLGRGTEALRLWVVSNDLHEVHGD--VTPEKALLLAPCKVIPLEYPNIQCTSVDLVVPTRAGRETPVTQLLEEL-
-TSSDAIVAYRGPHRWVRTLEPVRLEA-PPEPPTVLRKHGVYLLTGGLGKVGLTLAEYLARSVQAKLVLTQRSPFPDPRERHILALRELEK----LGAEV
LVLRADVADAEQMRTALSRAT-ERFGPIQGVIHSAGVLGDGAIQQKSPEELSRVLAPKVVGTLVLHDLFADAPLDFFLLFSSLSAIEPGFGQVAYSAANN
FLDAFVHGRM-ARAHRVACISWDVWRGEGMAYDALQKMKEEDFDQRGILRHEGV--------------------E-------------------------
------VFRRVLGS-RHVYLQVL---SELYLEASLHARP-------------KLGNSY-----ERPRGETEESLAPLWQELLGI--DGATDDFFELGGDS
LIGTQLISRVNRSFGVKLSTKSIYTHPTLRGMST--DEA-----------
>tr|S9QCF5|S9QCF5_9DELT Malonyl CoA-acyl carrier protein transacylase OS=Cystobacter fuscus DSM 2262 GN=D187_003411 PE=4 SV=1
DWFSVPSWKRSSRRPIEESTPEHWLLFVNGDRERHLLAERLRRGQHVVTVKAGAGFRQDGPNQFTLDAEHPDDYDALLRELQAQGLRPSAIVHAWSLSRP
EEDE--LASVEEARLGLDSVLHLARSFGLGTDPVRLWMVTNDMQDVLGE--ISPAKALLLAPCKVIPLEYPNIQCFSVDISLASRGPRGEPLEQLMEEL-
-GSSDPVVAYRHGHRWVRTTEPVRMEQ-APASASPLKQGGTYLITGGLGKVGLTLADYLARTYQARLVLLQRTPLPAPGERLLRNVRELEA----RGSEV
MVLSADVSHLEQMRAAVARAT-TRFGRIDGVIHSAGVLGDGGIQHKTQPELLRVLAPKVTGTLVLDTIFKDNPPDFLVLFSSLSSLEPGFGQVAYSAANN
FLDAFVSSRA-ARRYHVACINWDVWRGEGMAYDARQKLKEEDFRQRGILPEEGV--------------------E-------------------------
------VFRRVMGC-RQVYLDML---SQLYIETPGHARP-------------QLGNAY-----EPPEGETEKTLADIWQELLGI--QGATDNFFDLGGDS
LIGTQLLSRVRKSFGVKLSTKSIYGHPTIRSLSS--DEA-----------
>tr|B2J0Z0|B2J0Z0_NOSP7 Beta-ketoacyl synthase OS=Nostoc punctiforme (strain ATCC 29133 / PCC 73102) GN=Npun_R3430 PE=4 SV=1
DWFYIPSWKRTMPPQPIT-QPGCWLVFVDEFGLGERLVKQLLENQDVITVKVGEQFQQSSEYTYTINPEKEDDYNTLLKGLRTLGKIPRRIVHLWSVTSN
SYTN------SAIELGWSSLLFLGQAMSDKTDAVEIAIVSNNLQEVTGS-MLCPEKALVLGACKVMPLEYANINCRSIDVVIPESESGEQLIKALIAEL-
-YTSDQVIAYRGRNRWVQDFEPVQLHG-TVAGN-LLREQGVYLITGGLGGVGLLLAEYLAQTVQAKLILLGRSAFPDQDKQKIQKLQAMKT----LGAEV
MVVSTDVTNLEQMSAVLKKAN-QRFGEIHGVIHAAAVYGGGMMQLATKETVASAIAPKVQGTRVLETLFQESKLDFFVLCSSLSSFAGTSGMVDYTAANA
FLDSFAQYSA-AKYGFIKSINWDRWNNVGMAVPVH---ITGKELIAGMTAFEGI--------------------E-------------------------
------AFKRILCSSTQVFLSLIL--EEKLAQLSTHPRP-------------NLANTY-----VAPNNEIERNLADIWQQILGI--EKIHDNFFELGGDS
LFATQLVSQLCKVFQIELSYKGFFNGPTVADLA-VIVQK-----------
>tr|B9ZUK0|B9ZUK0_CHOCO Polyketide synthase OS=Chondromyces crocatus GN=cndE PE=4 SV=1
DWFYVPSWKRSLLPTR---STNSVLIFA-DARLAPPLAARLALDGKVTLVSPGAEYSRTESGHYTIDPRSSAQHHSLFSDLRARNALPTAIVHLWMTDPE
AVSP--AAPSESALLGFYSPLFIAQALALATAPVHLMLVSTHLQAVRGD-AVRPERAVLLGPCKVIPQEHRTVRCTSVDLDIDAHAAGTTQLDQLVAEL-
-DVRDAIVAYRGPHRWVQTLDPVQLSP-STGTPSRLRQQGTYLITGGMGGVGLAIATYLARTVKARLALVGRSPLPAREQQKLQAIREIEA----LGGEV
LPLIADVTHAEQVKSALEQSI-ARFGALHGIVHAAGDFGGNLIVRKSPEETTRIIAPKVHGLLHLDHALAGRQLDLFISCSSLTGVVGGPGQVDYVAANA
FLDAFAHSRS-GRPTATLSLNWDDWKDVGAAFKIR-AAWREEHYQTAMTTAEGI--------------------E-------------------------
------VLKRALAH-DQVLGPRMAEDLEQFGQRTARPRP-------------ALGTTY-----VAPRTPMERRLTEIWQDLLGV--DPIHDDFADLGGHS
LIATQLVSRLREAYRLDIPLRRVFESPTISDLAQSLLVA-----------
>tr|A0A0K2M6K0|A0A0K2M6K0_9NOST Uncharacterized protein OS=Anabaena sp. wa102 GN=AA650_10330 PE=4 SV=1
NWFYRQIWQPKSP-LINKDYLNLILVFLDSWGLGDYISRILSQYNPYITVSSGENFLEINNSCYQISPKEAEHYQLLFNSLANKNIVVGQIIHLWTYDEY
TGDIELEALKLAQTPGIYSLLFLVQALAKVDHSVKLLFISNHIQSILSTDLIAYEKSPALGLIKTIPQELPWLDCRHIDLTFGEVEKNGDY---ILQELQ
ISSKEREVAYRNGQRFVTRLEKVDLSKEPKH-PIPFQQGGTYLLSGGLGGVGVEIAKYLLRNYQARLLLIGRTPLPEKST---WDLHLQKKDLEQLGGEV
IYEAVDICDLNNLQAIVEKAKNKWGKNLDGIIHLAGRFHEQFVLAETQENLSALLRAKMLGSWTLHQLIKDKKDSFFINFSSINSFFGGSAVSAYAAANS
FLDCFSHYQKYQSALQSYCFAWSMWDEIGMSAGYQMKNLTRAKGFYAMPSSQAISSMLAALHHNQRHLFIGLDGNRNISRWQVET--ESLQKLT--AYFT
ASPVEIDADFQVKD-------DFGTVCTCKLVQVSEIPLTENGAIDRDKLVRRFI-RQETGVLIAPRNEVEEKIAQIWQQVLNIPSLGIDDNFFELGGNS
LLATQVISRIRKAFGVETSLQNLFQAPTIAQLSQLIAV------------
>tr|K6YQV2|K6YQV2_9ALTE Uncharacterized protein OS=Aliiglaciecola lipolytica E3 GN=GLIP_1058 PE=4 SV=1
AWLFQPSWQLTQP-VLIQSLAQKKVIFAHQNTISIELVNQLKTLGEPILVTGSDTLSLNGNDPLQIRSVQSEDYTAAMAHIADNKTSIDYVLCLWSLQDE
DDTST----WDENSPQLYSAIVACAGICSYDQQLQLMYVTQGAQSWQSSQV-TADNAGLPALIKTLKQELPDINYVHIDLALNEPDAASK----IIIELQ
SKQAGKDIIWSNQQRFSAELNPCRLTSIETD-PLAPNQPAGFVLSGGLGGIGQQLIKTLLHSAHAKILIIGRSSLEDVKQ---QHVNLSKWL----TANL
SYVTADVTNSEAVNLAVKTWLSEQQVTLHSIFHLAGGYHEATLQEESVQGFSDLAVAKLAGANSFANILTQFPAANLINFSSTAGVFGGATIGAYAAASC
ALDGLSHNLR-QQGLRCFDINWSSWRSTGMSEGNTAIEALRARGILELDIEAALNSLRLILGQGAGQYIVGLDPNPIIRRLMPN----CLNSLTP-TVFS
SEGTAGSEKLDFVD-------NFAQSFETPLLQIDKIPLLSDGQVDEAALTLIAT--QGNTEVVPAKTETEKAVVEIWKKILNLDTVSIQWNFFDVGGQS
ITATKLIAAIRTQFAVNWTLKDIFSAATCEQQAAAIEQ------------
>tr|A0A0P9KI65|A0A0P9KI65_9PSED Peptide synthase (Fragment) OS=Pseudomonas coronafaciens pv. atropurpurea GN=ALO66_04628 PE=4 SV=1
VWCEQLQCEQVSNSVATQVVARDLLLFEASQGKSQQLDPQSSAYNPGGLHLRGERFYEHHIDTLDISDLPGEERQARALQLDDHQLLVHIIADGWSLNVL
IDEFSQLAYWKQHSASRYSLRLSA--L--------SAAVRNTAQAWQSTSFMFYETQGLIRLPGLLAEELPWHSREKFDLQLHSEDRNGRL---NLFDYA
DELFERDTIVRLAQHYVRLLTQVQLLSAPAHVALQANRLAHYLRDKGVGPDVVDRLAYMLEDSGVELLLTGDLPSCTVAM---DMLHLDNWPLHLHGDNL
AYVIYTSGQKAPISFDVSVWECFWPLITGSRLLLAR----------PGEHRDPHRIAQMVNEYTLHPLLQLFIDPLTQQCSSLRRLFSGGEALPSELRNR
VLEQLPNVQLNRYGPTETAINVTHWGGIGLARGYLNRPGLTAERFIADPLGQPGERLYRRWAADALEYLGRLDQQVKLRGFRVEP--QEIEPQLI-GYYT
GAGQDVHAERLALE-------LPDYMVPAQLVRLDSMPLSPSGKLDRRALPEPQW---QTREHVEAQTDLQKQIAAVWRQVLGVLRVGLRDDFFELGGHS
LLATQIISRVRQACDIDLPLRALFEASELGAFAEQVQT------------
>tr|A0A0F7C1V4|A0A0F7C1V4_BRELA Uncharacterized protein OS=Brevibacillus laterosporus GN=EX87_22655 PE=4 SV=1
DWFYVPSWERVPLSGGYGAME-SVLIFADDTSLSKCLLEKLKQISTIVVVYKGATYRKIDDRSFVIHPSETNHYDQLLREMQELGFTATKVLHLWSVNED
KYELDTTRVEQAIDFGFYSLVFFVQALGRQMNPLDILVVTNNTQEVTGEEELQPEKATVLGFVKIAPLEYSNVNCRHIDILSIDPYKREKVAQQLLAELE
TVSEDKVVAYRNNYRWVQIMKKS--YWEARKSTPRLKQHGVYLITGGMGGMGFAIAKDFAQNYQAKLILIGRSEFPPRMNNSIQKIREILQLE-TDGAEV
MVVRADVSNQLQMADVIQC-ANERFGGINGVVHAAGIADYAGLINRTRETVETILKPKIHGTLALDYLLREQKDFVLCSSIGNVSYHRKVGQVAYNVANE
FLDAYAFYKTARDGVHTVSINWPDWQEVGMSIESAWAKALHTNLQDGLNQSEGVEVFKRALHSASPQVVV----SSEDLIKKI--------AEG------
-------------SAH--FQAVEQGQFSREINQ---RPKLS-------------------TNYVAPKSEIEGKLANIWQKMFGIEQVGIHDNFFDLGASS
LDLIQVNRKVKEMLNLDISVVTMYEYPTIASLAAYLIQE-----------
>tr|A0A068J4Q3|A0A068J4Q3_9BACT Putative NRPS/PKS hybrid synthase module E2C OS=uncultured bacterium PE=4 SV=1
DWFHVPSWERTVFPSDMGGWKENWLIIANDPELVAGFKATLEGRATVDVALFGTAYVHRDDGVYEIGAAELDDYVDLIGSLKLGSAGALNVLHLGGLCRR
A-VLVRGLVGPSQDHGFYSLVNLAKAIGEQDIPIRIGFVTSQVHEVTGEETLNPVMATALGACGVMPKEYPHVKSFSVDLPAIISVGFDIWVTRLLGEFH
SPEPGAVVAYRGQYRWKRTYVTQKDTGEGNHRLPGLRDRGVYLITGGTGGIGLVIAKFLAKTCRARLVLLKQSAFPAKSKDAERVLQALLEIE-SLGGEV
DVLACDVSDEDGMVNAVQE-VLSRHGAIHGVIHSAGLIG-VGLIANDRSAAEQIFSPKVDGSLVLYRALKDVSDVVFNSSITSV--TTPYGHVDYSAAHA
FLDTFAAYWSDHSEVRVLTINWPGWREVGMLANLK--PGLEKWLRRAIRTEDGLEAFRRALASGLPHLVV----SPEGLEDAE--------PSA------
-------------EL---LTRSPGGART----P---VEESR-------------------SAVDGPRDEIEQAVHQIWCNVFGISPLGIHDNFADLGGHS
LLAMQIVSRIRRTYPITYTLRRFFEYPTIAGTSSAIRAQ-----------
>tr|A0A0F9MHW3|A0A0F9MHW3_9ZZZZ Uncharacterized protein (Fragment) OS=marine sediment metagenome GN=LCGC14_1072140 PE=4 SV=1
NWFYQSNWQLSEPLINHVGKSKDVVYLCRNRSFLETLLATSG-------VNKHNVFADISTTVLSFNPLHSQLCNSFAEKLNKSNKMTL----V--YCDS
FLGADEHEQQVQNNNDFIALINIVAACVQQWVEIDLYVATEQVFRVDGNEQINTLSALLRGVVKVAPQEFSNVSCYHVDFASTGEKSSQRVASQLFSETQ
NHSANKEVAFRGNARWIRELSKFDR--IVDASERNLRSGAHIFITGGLGNIGMTLAKWLAEFGVAKVTLLSRKGKD-----SI---AAMP--K-LEHGEL
HIVQGDVSNFESLQSGLHD-AVARFGEIHTVIHAAGNIHDSALVDTDEVVCEQQFSSKVTGLLNLDCALESYNQCVLMSSVAVE--LGGLGFTAYTAANA
YMDAFCNKKQNEGDTAWISINWDGWAFGADAARSP-----------SLTAQEGVESMFWVLRMHSGVVIN----SKTNLHERT--------KKWIE----
-----------FEQDN--SAV---------LYD---RPELS-------------------KAYCAPQSETQKALVQLWQEALGISNLGINDNFFELGGDS
LLATRLVGNVCKRFNVTDAVKDFFAESTIISAAQRIDSH-----------
>tr|U4R4X2|U4R4X2_9FIRM Uncharacterized protein OS=[Clostridium] papyrosolvens C7 GN=L323_03305 PE=4 SV=1
DWFYLPLWKQSAPSILNGDNNKTWLVFTNNIGFNNNLLKALKEKEDVIKVTKGSDFNKVDDSEYTINVNHQEDYNNLLKELEKTGKLPSNILFLWGIDDD
ERTLDLNSIYEELDTGFFSLVYISKALLKQSDKVRIIVATNNLHNINGAERINPAKSTVLGPCKVIPQEAPFIECKNIDICIPDEVTR-KLIKKVLVDIF
DEKTETVVAYRNCIRYTQSYSPVRLTQDANRENSSFKNNGIYLITGGLGNIGLKLAEYLAEKYSAKLILTGKSEFPRRDDEQIMKIQNLLYLE-KQGAKI
LTYTCDVADQESMKGIVDE-AERHFGHINGVIHAAATMRDSLTVQLNKEDCIEQFIPKIHGLLTLHKVFKDREDLTVTSSTSAL--LGGLGFCAYSAANI
FMDSFVNEFNRVASKEWLTVNWEGWRFSSDKTQFSFSTSM---DELLMEPEQGVEAFERIMNPGIGQVII----SSGDFNKRV--------DRWIK----
-----------LDSIK--SAESND----NGNKQ---RPNLK-------------------NSYVMPANKLEETIAKVFADFFGYDEVGIDDNFFDLGASS
LDMIQITNNLRRQLNTNIPILKLFTFSTIRTLAGNLQNS-----------
>tr|A0A059VU53|A0A059VU53_STRA9 Beta-ketoacyl synthase OS=Streptomyces albulus GN=DC74_397 PE=4 SV=1
QWFSTPVWRQAIGTLDAAEPIAPVLLFADAGGTAARLTR--HAFGEVLTVTAGTDYAR-DGDTWTIRPDSEEDHARLVGDLLAEERLPDRVVHAWSTAPL
PAERGKERFEQAQRHGVYSLIALVKAVSAHGHPLQLDLISAGAYALSPAEPEAAELAPLAVAARVIGQEHGNIGSRHFDLPGTDDRSR-----TLAAELA
RRRPEVATTLRGATRWIADLEPVR-ADWTAKATSRLRDGGVYLITGGLGEIGSTLAHWLRRECPARLALLTRDPLPPREDDPTLRMTRLRALA-AEGPEP
LLVHADVADEDALRTAVEQ-VTGHFGALDGVVHAAGLPSEQWAIAASVEQCQWHFAPKAHGQIALEKVLADHPDCLLLSSLAGV--LGGLRLLGYGAANH
FMDVAAERANRLDRTVWISAAWDVWQHHQDEKRAIIGRSM---DDKAIQPEEGLEAVRRLLTRDVSHVAV----STWDVAHRL--------DQWVR----
-----------DERIA--RPT-TGGT-----AA---AAADG-------------------AGPDGGADDLTEQVARLVRGALGREDMPLDGDIFEFGGDS
LLIVRLLSDVRDQFSAEVPLADVLGEPTPRALARFVQER-----------
>tr|W4LVP7|W4LVP7_9DELT Uncharacterized protein OS=Candidatus Entotheonella sp. TSY1 GN=ETSY1_05325 PE=4 SV=1
DWFYVEDWQSKGLEEV--GSMSNWLILTQPEQLR-----WLAEQASVVVVQPGAGYARREAGDLTINPDEPSDYDRLFAELLAGGMFPARIVHAWKWGRK
EEVTVLEHLDAEQKLGLYSLQYLIQALGRLRHPVRVDVISDQVFAVMANESVYPEHATLIGACKVIPLEYPDVHCRLLDIPVGEA--------SLQQELG
ADTQDPLVAYRDGKRFIPGVKPRP-LDEACENLAHLKSGGTYLITGGLGGIGHAVARFLARTVQANLVLVGRRPLT----EQDQRMSRLRELE-SLGARV
LYVAADVAELASMRQVIAQ-AVAEFGPIDGVVHSAGVADSAGAILRTREMTEEMLRSKVRGTLVLEAVLAGQPDWALFSSISNVLYHNRYGQLSYVAGNS
FLEAFAARLR-HRGQFAVAIAWDEWQDVGMAAEVAFAASFGKQPLDSFSPQDGERAFHRALASDVATVMI----STRDLRLRI--------RLD------
-------------VHA--KSPFEA-AREMAVNA---GVASP-------------------SNQDMASLSGKQQIAQMWQRILGVADIGHDDNYFALGGDS
LSAVRFLAEVNREFGEQVPFAAMVEFPTPAMFAEYLELD-----------
>tr|C3I386|C3I386_BACTU Polyketide synthase type I OS=Bacillus thuringiensis IBL 200 GN=bthur0013_32170 PE=4 SV=1
EWFYTPQWKSSTLFEPNHDVNETWIVFVDQEGLGNELVKDLNKGQRVVTVEPGFAFNKENNDRFIINPEERTDYVKLLDEVQEIYGLPTRIIHMWGITNE
ERQASIEYVNCKQNLGFYSMFYLTQALGDKNISISIRIITNGVQQVIGDEELIPEKSTVLGTSLVVPQEYSYLSCSSVDVVLPLNKEKNRLINQLVEECL
SNTNDKMIAYRGNKRFVQTFEPLQLEQPAKEK-LPLRKNGVYLITGGLGGIGTILAKHLAQTVQANLVLLTRTGLPNLKEMYSDRILEIEE----TGSKV
YVLAADVTDQSQLYEAIHKAEQKFG-KINGVIHGAGILGGKTFNLIQKEDCEEQFSAKIYGLLNLEECLRNKDDFCV-LMSSISAVLGGLGYVSYAASNI
YMDVFAQYINRYSKLPWISVNWSDWKYWEDEEDMQIGASVHELSMTPEEGVQAFNIALWKQGEV-----L--IHSPGELQARID--------QWV--LLN
SFN-DEKE-------------EELDSTLYHSRPQ----------LLT--------------EYVAPRNEVEEKLSKIWRNIFKVSEVGVHDDLLELGGDS
LKAITIVSKIHKEFNVEVPIKELFTLSNIEKLANYISRADK---------
>tr|A9AV11|A9AV11_HERA2 Beta-ketoacyl synthase OS=Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785) GN=Haur_3967 PE=4 SV=1
DWYAVPSWKRAVAHDELAGDQGSWLVLADGEGLAAGLTAWLERGQTVITVTPGAAFAQHSATAYTVRAGSREDFTALLQTLERHGQMPSRIVHAWLATPK
VGAAQLVGLAESLDLGFYSLLALAQALGEQDIWCEINVLTSEMHDINGREELNVAAAAVIGPCKIIPVEYPNLTARSIDILLPASAERATLVAQIGAELA
TPPTGDLVAFRGAHRWVQMMEPVALPTAPASH-PRLRTGGVYLLTGGLGGIALGLARDLAATLQAKLVLVNRSSLPDLEAGVGRRILDLEA----LGAEV
LVIQADVTDAVAMARAVAEAQARFG-TIHGVLHTAGVPGVGLMQLKDAATAAAELAPKVQGTLALTRALAGVPDFLV-LFSSVTSATGGPGQVAYCAANA
FLDAYARKHATDHGRSWGEWLWDAWSDSAEDQ-LRFRAYRRTFGITFDEGAEALRRILACRISH-----L--FVTTEDVVAMFE--------DSK--GSA
LQR-AA---------------RQEDAAQRYPRPE----------VST--------------SFVEPQSELEQQVSAIWSEVLGIAPIGVNDNFFDLGGNS
LIGIQIVTRLRRTFQVALPLTILFDAPTVEEMSIAIEMMLI---------
>tr|A9AV07|A9AV07_HERA2 Beta-ketoacyl synthase OS=Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785) GN=Haur_3963 PE=4 SV=1
DWFAAASWKRGLPFDAEAKESRCWLVFQDACGVGAGLAAWLERGQTVITVTPSAAFTQLGDSHYSVRPAERDDCTALLQALERQGQTPSRIVHAWLVAPA
DHASDLVVLDQTLQMGFYSLLALTQALGDQGVGCQIDIMTSDMQEVTGHEPLQIAKATVIGLSKIIPQEYPNLTARSIDLSLLAGLLSQQLIAEIATELV
HPPTGDQIAFRGIHRWVQVFEPLNLPAAPASH-PRLRMGGVYLLTGGLGGIALGLARDLAATLRAKLVLVNRSSLPDLEAGVGRRILDLEA----LGAEV
LVIQADVTDAVAMAQAVNQAQACFG-TIHGVLHTAGVPGVGLMQLKDAATAAAELAPKVQGTLALTRALAGVPDFLV-LFSSVTSATGGPGQVAYCAANA
FLDAYARKHVTDHGQSWGEWRWDAWSEPEEIQ-AKFRAYRSTFGITFEEGAETLRRLLARRFPH-----L--FVTSDDLLAMVE--------GSK--QIF
ASGGVGNQ-------------EQESVRSTYPRPE----------VGT--------------SFVEPQSDLEHQIAGLWSELLGIAPIGANDNFFDLGGNS
LLGISLFGRMRKTLKLKLPAHVLYEAPTVKAQADYISQEQA---------
>tr|A0A066TQ73|A0A066TQ73_9PSEU Uncharacterized protein OS=Amycolatopsis rifamycinica GN=DV20_37350 PE=4 SV=1
QWLNLPTWRQTSAAPAA-PRPASWLVFAR-PGLAEDVLGGIRTGDPVTVVRPGAGYRPGP--DATVRPGDIGDLLALLRDLKRSGTRLDRVVHLWNLDDG
D----------ALSLGLHTLVALARAAGELGLW-TLDLAATGTQRVLHDGELRPDAATLTGPNLVIPMEYPGVQTRLIDVDAAAGV-------GVVAELH
RPAPGRTVALRGSRRWLPGYEVLAPQPIEQAR-EVLREHGVYLITGGLGGIGLAMAERLARDSHAKLVLFGRRGLPPAAETIRDRVLAIEA----LGGEV
AVVEGDVAEEADVRRAVAVAVERFG-ALHGILHTAGVPGTGLMQFKEPGDADQVLAPKLPGSRALSAATEGLDDFVA-LFSSITSVTGGPGQVDYCAGNA
WLDAYAAGH---GGRSWGEWTWNAWDDEEDIQ-TYFREHRAKFGIDFEQGWRTLLRALASGEPH-----V--VVSTQDLPAVTA--------VAA--RFS
VDA-VTSA-------------AHGKTADRHPRPE----------LVT--------------PFQEPEGDAERAVAEAWCDALRLDRVGASDNFFELGGTS
LLGISLLATLRTAYPDELPPHIIHEAPTVAALAKIAAGGPE---------
>tr|A9AV10|A9AV10_HERA2 Beta-ketoacyl synthase OS=Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785) GN=Haur_3966 PE=4 SV=1
DWYAVPSWKRAVAHNIV-TEPGCWLVLVDGEGLATRLTAWLDRGQTVIAVTPGAAFTQHSATAYTVRPASREDFTALLQTLERQGQTPSRVVHAWLATAG
DPAADEAGFDHTLQHGFYSLLALAQALGDQGVWCEINAVTVAMQEVTGQEDLRIAAATVIGPCKIIPVEYPNLTARSIDILLPASAERATLVAQLGAELA
TPPTGDQVAFRGAHRWVQMMEPVALPAVPASH-PRLRTGGVYLLTGGLGGIALGLARDLAATLRAKLVLVNRSGLPDLEAGMGRRILDLEA----LGAEV
LVIQADVTDAVAMARAVAEAQARFG-TIHGVLHTAGVPGVGLMQLKDAATAAAELAPKVQGTLALTRALAGVPDFLV-LFSSVTSATGGPGQVAYCAANA
FLDAYARKHATDHGQSWGEWLWDAWSEAPEVQ-AEFRAYRKNFGITFAEGAEALRRILACQIPH-----L--FVTTEDLLNMFE--------GSK--RSA
ART-QAEP-------------TEQQARTRYPRPE----------VG---------------SFVEPQGELEQSIARVWADVLAIEAIGANDNFFDLGGNS
LLGIGLINQLRRNLKLKLPAHVLYEAPTVATLADYINQS-----------
>tr|I0F1D5|I0F1D5_9BACI Polyketide synthase subunit OS=Bacillus sp. JS GN=MY9_0752 PE=4 SV=1
QWFYLPSWERKIKSADSKAESGKTLVFHEGTAFGDRLVQAMRQGHETVIVTRDRQFKKINSGLYVINPSDGTHYERLFSSLASDGLLPNCVMHLWSVSEQ
EE--SYKTFSTYSENGYYSLIFTAQAASNQKQECNMFVLTSGIHEVTGEEQINPEKSTILGPLKVIPQEYNHLKCWNIDIPPLPDLTEEELIDQIMMETD
AAGEDQIISYRNRRRWVQMYQPVQLNKASGLP-NMIRPKGVYLITGGLGGIGFVLSKLLAQEGNVRLILTGRSELPQCEDPTSVKIKELER----LGAKV
TALQADAGSLSDMQAVMRKIHTEFG-ELNGVFHAAGLPGSSSFRAITIEGGEDQFQSKVRGLKVLESLLENENDFCF-LFSSISALLGGLGFSAYSAANI
YMDAFAARVNQRSKTPWVCVNWDAWNFWGQLE-STIGESIAELAILPEEGAALFQYVLDINNRH-----L--LVSTGDLGHRMK--------QWI--SMN
ADS-IAKE-------------E-KKAGALHTRPE----------LNN--------------PYVAPRNKTEQVICGIWQDFMGLEQVGIHDNFFDLGASS
LDIVQVTNRLNKELGTNEAVVTLFTYPSVAALAQFISPDQE---------
>tr|H3SBB7|H3SBB7_9BACL Polyketide synthase subunit OS=Paenibacillus dendritiformis C454 GN=PDENDC454_04014 PE=4 SV=1
DWFYYPSWERTVLQEVPDDGRHDWLIFADGCGLADELAALAQEGHRAVKVEAGTAFAKRDPDTFTLAPAVAEQYALLLEELRAREFTPDRVVHLWNVSPA
DEKLPDESEGRQQELGYYSLIFLAQALRRQKEDVRIAVVSTDMQEVTGLERLSPGKMTLLGPSLVIQQEYSGMTCVSIDIDAPEGGHHRRTAERIAAELS
VPASDRLIAYRGPYRWVQQYKPLALRQADPPA-APFRERGVYLITGGLGGIGMLTAEYLARHYRARLILTGRSSFPALAEPSSRKIQQLEA----LGAEV
TYIQADLSDEAQMSRVFESIDAAYG-GVNGVVQAAGLPGTESFRAIEGGQTDEQFRAKVQGLQTLSKLLAGREDVCI-LFSSIASVLGGLGFSSYSAANL
YMDAFARRQNRAGGTKWLCVNWDAWEFWEEHR-STIGESLVELAILPAEAPDLFRYVYRCGSNQ-----I--IVSTGDLDMRID--------QWI--RHA
G---KKKE-------------EPAGSGTTFGRPN----------LTN--------------PYVAPRNRIEKTIADVWKQFFRMDEVGIHDNFFDLGASS
LDMIQLTGKLNEALGESIAVVDLFTYPSIHALAQRLTRNGQ---------
>tr|A0A0M0VXU2|A0A0M0VXU2_9BACI Polyketide synthase subunit OS=Bacillus sp. FJAT-18019 GN=AMS62_15360 PE=4 SV=1
DWFYYPSWERALLEEQPHHNSHNWLVFKDDCGIADELAASINMGERTVMVKAGNAFCAHENGTFTLSPSSAEHYVRLLEELQKRDFVPDRVAHLWNVSSS
GDEEEEAVERRQQEEGYYSLIYLAQALRKHKEDIRIAVVSSGMQEVTGMERLSPGKMTLLGPCMVIQQEYSGITCVSIDIDVQEERQKRRIADNVILEIS
SPPSDRLIAYRGSYRWVQNFKPVELRQAEKPA-APFRQQGVYLITGGLGGIGMLTAEFLARNYGARLILTGRSSFPDLAEPLSRKILQLEE----LGAEV
TYMQADLSNEEQMRDVFKFIDREYG-RLHGVVQAAGLPGGESFRAIEGDQSDEQFRAKVQGLQTLGRLIADREEICI-LFSSIASILGGLGFSAYSAANL
YMDAFARKQNRAGGTKWLCVNWDAWEFWEEHR-STIGESLVELAITPAETPDLFRYVYPCGSNQ-----I--IVSTGDLQTRID--------QWI--RHA
G---KKED-------------SHAAGGASFSRPD----------LTT--------------PYAAPRNRVEKTIAEVWKQFFRIDEVGIHDNFFDLGASS
LDMIQVTAKLNEALDESIAVVDMFTYPSIHALAQRLTHSEE---------
>tr|A9AV08|A9AV08_HERA2 Beta-ketoacyl synthase OS=Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785) GN=Haur_3964 PE=4 SV=1
TWSAIGSWKRSGPAASARNEPHYWLMLVDDDGLAVDVTAWLQRGQTVIAVTPGAAFAQHSATAYTVRPASREDFTALLQTLERQGQTPSRVVHAWLATAG
DPAADEAGLDHALDHGFYSLLALAQALGDQGVWCEITVITAAMQEVTGQEDLRIAAATVIGPCKIIPQESPTLTARSIDILLPASAERATLVAQIGAELA
TPPTGDLVAFRGVHRWVQVFEPLPLPAAPASH-PRLRMGGVYLLTGGLGGIALGLARDLAATLQAKLVLVNRSGLPDLEVGVGRRILDLEA----LGAEV
LVIQADVTDAVAMARAVAEAQARFG-TIHGVLHTAGVPGVGLMQLKDAATAAAELAPKVQGTLALTRALAGVPDFLV-LFSSVTSATGGPGQVAYCAANA
FLDAYARKHATDHGQSWGEWLWDAWSEPEEVQ-ARFRAYRSGFGITFAEGADILRRILAEPLTH-----V--FVTSEDLLPMAE--------RSR--RSS
A-ARAALR-------------EQQSARPTYPRPE----------VG---------------SFAEPQNDLERQIAGIWSEVLGIAPIGANDNFFDLGGNS
LLGLELFSRMRKALKAKLPAYVLYEAPTVATQAVYLAPTPQ---------
>tr|A0A0H0SSK8|A0A0H0SSK8_9BACL Polyketide synthase OS=Brevibacillus formosus GN=AA984_04320 PE=4 SV=1
TTMLTPVWNAVLVEKGE------------------------ATSEKVVIVCAEEKLQRHYPQASVIQLQPIDSIEVIASKLEEQGMIN---HILWVAPDS
PVDSVKESLMNEQERGVIHVFRLIKALLALGYDLGWTIITVQAQAINKKDKVHPTHASIHGLIGSMAKEYPNWKVRLVDLEA---AELRDVF-----ALP
ADAHGNAWAYRRHAWYRQQLMPVQSPSIN--Q-TVYRQHGVYVVIGGAGGIGQAWSEYMIGTYQAQIIWIGRRKKDE---SIQNKINQLAS----LGPAP
HYIEADATDRESLQSAYEEIMKQYG-KINGVIHSAIVLLDRSLANMDETTFRAGLVPKVEVSVRISQVFGQEPDFVL-FFSSINSFTKSPGQSNYASGCT
FKDAFAHQLAKEWTCAVKVMNWGYWGSQERME------QIGIGSIEPSEGMEALEALL-GPMNQ-----V--ALMKTTKPLEME--------GINTSSMA
SIQNKVKE-------------MP---KAAYFASE----------ADT--------------GADSLFDDVQATIIQLASQILKVEEIDADIELKEYGFDP
VKLTEFSAKINQKYKLELTPAVMMDYPTLKHMTEFLVNTTL---------
>tr|A0A0F6Y0Y3|A0A0F6Y0Y3_BRELA Beta-ketoacyl synthase OS=Brevibacillus laterosporus GN=EX87_22650 PE=4 SV=1
EWFYTPQWSSVPLQKAKSLAEQRWLIFTDEGGLGTKVAAGLTVAKSVVVVKVGETFEKLAENCYQLNLKEESHYSMLLSELSEDDKLPTRIAHFLGVTSI
EGNAALRLSD-FQERGFYSLFHLMKSLVGKQIQIDIKIISNNVHEILGDEPLIPEKATVLSPAIVAPQEYSYLNCSHIDIVFPSMSKEKKLVEQLMAECC
SPSTDKLVAYRGKNRWVQGYVPQSLDNGEETP-SPLREKGVYLITGGLGGIGLILAEYLVKTVRAKLILTGRSGLLGIEEPISQKMQELEK----MGGEV
LLFACDVADKDQMQAVITQAEQIHG-SLNGVIHGAGVLGGNTFNLMKKTDCEDQFKSKMYGLRVLSEVLREKQDFCL-LMSSIASVLGGLGFTAYSAANL
YMDYFVQKYNRDALVPWISVNWSDWKYWDETEDKTVGGSIWELSMLPEEGVQVFQRILSG-ETW-----V--ANSPGDLQVRIN--------QWV--HLQ
SLR-SEEE-------------NES-EVVLHARPM----------LMS--------------SYVEPRTELEKELVEIWQKIFRVNQIGIEDDFFELGGDS
LKGITLVSRIHKELHVEIPVAQLFDTPTIETLCTYIQNAEK---------
>tr|A0A078L2Z9|A0A078L2Z9_9GAMM Polyketide synthase PksJ OS=Legionella massiliensis GN=pksJ PE=4 SV=1
--------------------PKTWFIFANEQQPYLE-QCIRDAGHFLYTIKSGKEFKQLTDSSFVIDPTQKSHYGKLLGLVKIRGE-QGVILHAWLLENG
NSK-------TTLFDGPFSILYLSQLLSE--LHPKIQFNLTLASNLFGNEQIIPIKAAVLGPCKVIPLEQENLFCKVIDLDQKEKI-TAKLANALFHDMT
RDCAKDEIAYRAENRWIRVLDPCSDYLES-LNSPRIKTKGVYLITGGLGGIGLSLAQHLATNYQANIILLSPNLLSLEQDEKLKLLADIRSKAE----SL
TIEQASVENKSRIRGIVKSILEKFG-RLDGVIHAAGLAGGGVAQLKTLDEYNRVLEPKLQGTETILKALYDVPLDFIVFLSSTTSILG--YPGDYCSANR
VLDAFANTNPFKHPVFCVSMNWQAWRDVGMAAESETKSLNESNSYTAREAVILFEKIVNSDLN--QVIISKSDPNKL---------------HISI--NS
------------------LAKDP--------------------LPSIES--------------SVDDNGITSLVLQIWRDILGINDIGLDDDFYELGGHS
LLAITLLAKIKKQFNTKIPTAALFEAKTIRSLSELIQTY-----------
>tr|S9U975|S9U975_PAEAL Amino acid adenylation protein OS=Paenibacillus alvei A6-6i-x GN=PAAL66ix_19044 PE=4 SV=1
----------------------VLLIVGEHWQEQLA-NKFRGEGMDVVQMYFSPQYRQLERQVYEVNINKEDQIADVLKQLRDSGQIVNTCIHISSSQPL
QDR-------MVVDGILAPAWYLTRQLAL--HTAATPARFHITRNASGDAIVDPLQSFIVSLNRSANHEYPLLESRCIDLEASEWA-KDVSLQHIYNEVC
WHDETKEVAYRHATRYVRYLKESV--PSK-TKRELFRNDGVYLVTGGTGGIATEICRAIASKYRATFVLLGRTREENM---SQRQLADIRALAELG-ADV
QYFAVNIAERNELESTVERISTQYG-NVDGVIHAAGVLGKRVLLEASMEDYQDVYEAKVYGTVLLDMLLREHMVDFFMTFSSVDAILSEKNLGHYTSANH
FMDQYALQQRQLGRQ-FISIQWGGWQFTGMGSKNEELSHIHELGYDRKQGIGAFWTITGARSS--HLMVTGLDEQDL---------------QALDKYFK
------------------LEPDLRKRM------------NASSAKPSIA--------------DISLESIESTVARVWTEMLEMEQPDVNENYFSIGGDS
ILGIDITVQLSQIYQLQLDANTLFRYDTIRSLSRFIHEQ-----------
>tr|V9W6M6|V9W6M6_9BACL Putative non-ribosomal peptide ligase/ polyketide synthase hybrid OS=Paenibacillus larvae subsp. larvae DSM 25430 GN=ERIC2_c180
--------------------VTCWLIFADGIGEYMA-ERLKKDHRHVITVDIGTGFRKISEQEYVMDPGIPANYQALFSELQASGRFPDRIIHLWSISSS
STS-------QAQDAGFYSCMYIAQSIGL--LKVTKQIRAVITSNMTGEEALNPEQATVLGFVKICPLEYANISCQSIDITTNIET-PD-LIERILGDIS
APQPDLMIAYRGSYRWTPLYKQVQLDNNG-LSAERLKENGVYLITGGMGGIGFAMAQHLSKRIRANYVLLGRSPFPDRQESTIKKIRGIQGMEENG-SEV
MIVSADLSCSEQMEEAIARIRARFG-KINGVIHAAGIADYEGIQNRTKEMSEKILAPKVKGTLILDSLLEDEELDFLVLFSSNGNMSYHYKFGSYNAANE
FLDAYANYKRASSKAYTVSINWCDWKDVGMSVEAAEKERLKTAAITISEGMDVINYVLSSLLS--RVIVSPVDLQAE---------------IAFEEFLK
------------------MVKDQETYSL----------KEQGAETDRHM--------------PAKTGEIQNTLISIWTDLLGDEEIGIHDNVFDLGANS
LDMIQANSRLKAIMKQDIPIVTMYTYPTIHTLAEHLTRG-----------
>tr|V3T1K6|V3T1K6_9ENTR Beta-ketoacyl-acyl-carrier-protein synthase I, 6-deoxyerythronolide-B synthase OS=Serratia sp. ATCC 39006 GN=Ser39006_03352 PE=
THSYTPMWLADGAVTA-CEGEGCCLLLCQQQGLQSNLQRLWASGMQSLLVTHGEKAGQDSDDSFTACFSDVQQLTACFRRLKQASRLPRTVVHYGSGENS
EDAQKAL----------SGLVNIIRAYKAGDAELKLLIITQYLYSDKGGS-ESACQAVKTGFARVINQEYRDIHCQLVDFESDKV---ADIAAGLLFELA
NPSGQVIVLYREAQRWLAHWQSSRLTGQQ---SPGFRQGGVYLITGGLGNIGFALALRLIHKFQAKIVIITRSDGLS--DYQQ-------QQLSGKQNNL
LICQGSCANPDQLQQSVTEAE-QVFGPIQGVIHAAGWASEESVENMDEAFIRRHFNAKVAGTQALVQIFADKSLDFCLLMSSISAQLGGIGMAAYAGVNH
YLDCMARYQR-SKGLPWISVNWDRWQGARGWNNAYLKRVLGERQIAVEHGLDCIEHIVQNTANCQLLVSGK------DVLGQLNTQN--H----------
------------ISIASATVADET-----------------NGLPLRV--KDRTH---LNSRFVDARNPLERLITDVFEEHFGFSGISIHDNFFDLGASS
VDLVRLHLKLNKRVDTPLTIANFLNYHSIYTLARFIEGDAATDE------
>tr|D3HQ94|D3HQ94_LEGLN Putative polyketide synthase of type I OS=Legionella longbeachae serogroup 1 (strain NSW150) GN=LLO_0722 PE=4 SV=1
DWCFQLQWQHQPCIKNQKIQDNHWLLLG------KHLSRFQAQGLSVVSEEDNYPLEKLNGVLFAMGLDFPNDIESNV----------------------
-------TFQK---NTLKRLLALIKELNQKSIKLQLIVLTNAITELAAGK-LNLSNSPLIGFCRTLVLELPQFHTVLIDSEKTDD---EHYIAQVIDELD
DPYYEHIVAYRDKKRFIARLKKNKLVDR----RRSLYGEGRYLVTGGCGGLGLVTAQALLSSGAREVILTSRNVNKP--AIEEAI---KKLKYNYTGRTI
RAISLDVTDKEKLQALLVDLN-S-DGLLKGIIHAAGAAVKAALIEHTDNDIDHLFSAKVLGGWYLHELSQNIDLDFFVVYSSISSVFGSNKESVYSGTNS
FLDALIAERQ-RLGMVGTAIDWGPWGEVGMAKKRSQDQGLKQSLISNEQGHAFIKILINEQLSHAAIISPD------YLKFML-DFV--P----------
------------KPLPAFLANILI-----------------GVGQVSDQDYLEVN---VENRLQAC-IDLVTSICKEILEISDAEDLDENEGFFELGFDS
LMITELATKLKENLAPTVTATIGFDYPSINKLAQYIESELDKHL------
>tr|W0BHC0|W0BHC0_9GAMM KR domain/condensation domain/beta-ketoacyl synthase, N-terminal domain/beta-ketoacyl synthase, C-terminal domain/phosphopantet
EWAFQVQWEAVALDRNNKIQGNTWLLIG------KPLAGFRAQGLQVILEDESYSLDKLSGIIFAASLEPANDIDVMI----------------------
-------DFQK---NVIKKLLNLLKELNNKAVELQLIVLTNGIAELPAGN-LNLSNAPLVGFCKTLVLELPQYHTLLIDVDNAGD---EHHAGRVVAEIH
GDCYEHIIAYRNDKRLAARLKKITLTEK----KQTLNSKGRYLITGGCGDLGLVTAQALLSAGARELILISRQVDKP--GLKESI---KKIQLTYSDATI
RPLSLDVSNKEELRHLLSELN-E-DGLLKGIIHAAGVAIKAPLLAHQDENVDYLFSAKVNGGWYLHELSQGCNLDFFVVYSSVSSSFGSNKESVYGAANS
FLDALMAERR-RLGLVGTTIQWGPWGEIGMAKQRSRNQDLKRALIDKEQGFSFIKILINGELEHATIISPD------YLKFML-DFV--P----------
------------KPLPVCLVDELT-----------------SVEPI-SQAYLKLD---DHRRFKAC-RDMVSDICKEILELSATEDLNEDDGFFEIGFDS
LMITEMATALKKKLEPHITVSIGFNYPSINKLAKYIESELNDYL------
>tr|K2KT85|K2KT85_9GAMM Beta-ketoacyl synthase OS=Idiomarina xiamenensis 10-D-4 GN=A10D4_11184 PE=4 SV=1
HWWYKPVWRESTLKQRNSAAAERLLVFCDDLGYAKAANRIQSTQTDSILVIKGDGYSRLDDNSFQIRATHPEDYDRLIRQLQREARLPSKIGHFFTVTDG
QEPQAQMLEL-----GYFSLMWLVQAFGKLLDPLDIIVVSSGIHEVVKGEIIDPYKSMILGPCKGISQEAPHILLRNIDICVDNS---TDLVQALRKELL
AQPKDPIVAYRGGVRLLQDFEPFLVESIH---DAVLKQHGVYLITGGLGGVGLVLARHLAKKVQAKLVLCGRSALPE--REQWSQWLRKIQELESFGAEV
IVLSVDAGDEQQLKAVIDKTY-ETFGTLNGVVHAAGISESWAFKDVARDDSDYQFRPKVHGVIALQKALADKQLDFVVLTSSVSAVLGGMTLIPYAAANI
FMDNFTRIHR-TAVTRWLSVNWDTWRLSESQHETV-GKTVLEFEMSQQEGAEAFERLAYYMPSDHIVESTG------NIQARLDQWV--R----------
------------E--PFNRVNSAE-----------------PVVKTQL--YARPA---LSTTFIASSNEVEERVSKVWHNVLGIEEIGIHDNYFDLGGTS
LTAIQLVAELQREFSVPVSPVVIFEAPTVHELAKIFDDGAHKDK------
>tr|A9AV09|A9AV09_HERA2 Beta-ketoacyl synthase OS=Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785) GN=Haur_3965 PE=4 SV=1
DWFYTPVWEAQPLPAKGAQPAGPYLVFVDEQGFGAQVGRLESNGVTVIKVRQGGAFAQLDATSFAVRPDIRDDYAVLFSALQTNRLLPQAIVHLWNVASN
ARVSADEAGFGAQVYGFYSLLHLAQAVGGLESTLPITVFSNSTQPVTGNERLYAEQSPSAVTCRVIGQENPAVFCRNVDICVPEQ---AGLAMLLEQELL
VPSQDIAVAYREGRRFVQHYRADRLEPIV---PAPLRMGGVYLITGGLGGIGTAIAGYLAEKAQAKLVLLGRTPLPP--REEWDGLAAKIRAMEAHGAEV
LTLSADVGDPAQLSAALAEIR-RRFGALHGVVHGAGHLDQSGFQDVGHEPCEAHFKPKVYALYHLEAMLRDQELDFCLLLSSVSSVLGGLGYVGYTAANY
FMDIFTHRLQ-SPSNRWISVNWDTWHLKAGQHDG--ATV-AQYELFPFEGVDAFGRILER-APVQIINSTG------DLDTRIKQWV--L----------
------------L--ESIRSNAA------------------SSSPAAS--HERPA---IDTQYVPVNSEYERRIAAVWQQVLGIGQIGIDDNFFDLGGNS
LTALQLISRLKKEFKTQISAVAIFEAPTIRAMAQYLMPDAPPAV------
>tr|C7Q561|C7Q561_CATAD Beta-ketoacyl synthase OS=Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897) GN=Caci_7000 PE=
VEVLRPRWSAAPIAAGA--ALGKVVLVADTGGVAEALEVLTASGAEVVTVSGGTALTREEHAAIVAREAAEDRTTVVD-----LRLLDR-----------
--PAGDAADLDGRDVVQ-PLARLLDAWG-GTGSARMLVATRGGQPVGGDVPRPA-QHAAAVLQVVANLEYLNLECGTVDVGADAD---A-VAAALAAEIP
SDVDDVLVGYRDGERHVRDYVPADAAPAP---VHRIRSGGSYLITGGLGDLGMILAEHFAASGAGRLILTSRTGSPA--GG--SRL-DRLEALRASGVEI
LTPAVDVTDADAMRAVLADAL-ADGRRLDGIVHAAAVTHPDTFRAVDDEAVGLHFGAKVGGALVLDTLLETQAPEFCLLFSSTSSILGGIAFACYAGGNA
ALAAIGQRNG-QSPTRWISTSWDTWSVTIDSHHV--GAVMVKHSMTREQALAAFDATLAG-PGPSLVVAAG------GLTDRLPRAM--T----------
------------L--TDVI------------------------GGGEK--FPRPD---LPQPYSAPSTDTERSLADLWSHLLGVEPVGVKDAFFDLGGNS
LLALQMLALVKKRFGVAIPAVTLFEAPTVQGLAAILDNQGATDK------
>tr|F5LIX5|F5LIX5_9BACL Phosphopantetheine attachment domain protein OS=Paenibacillus sp. HGF7 GN=HMPREF9413_5748 PE=4 SV=1
NAFYGTNWMLQPAIQKTQNVQGNVLVFCDQGEYARALAEQIQHQDRLFFVSIGKKFSQID-ATQFTVGEDEEDYDKLLA---AIGVNLCSVYHFSTVNFT
RTDVSAERYGEELHQGLYSV-VYLTRAILIRDSVEFV---LLTDYAHEVACIKPANAAFLAVAKSTATEYPNLRYRCIDIDEAT------DMETVLDEVL
TENPTFRVAYRNNQRFTEALTVIEQKQ-ESMREMEIKQTGVYLITGGTGGLGLQMAIDLGNRGARTICLLARKALPDRSTWQIESILYL----ENLGCTV
LLRYTDVSDRVQMESILSEL-KEAYGPINGIIHCAGMAGDGFLFNKNMNTFRDVVRPKINGTVVLDALTRGEKLDFFILFSSMTSLLGGPGQSDYTAANA
FLDAYAPYLR-KKGIPVQTVNWPGWSEVGMAVDYQVAD--AVTLFRSLETEVAIQALNEIIKYDLSNVIPGINYDIL-QQ--IGENN-----LP-FRLSP
WLKK---------NLDRHI-SRHQKKQVAKQTIAPDIH-----------------IIG---KN-DNYTTTENEVAFRYAVVLDLREIDIYESFNSLGGDS
IHAMELLKEINAIYPRTIDITDIFTHSSVEELAGLIDKK-----------
>tr|K4Z767|K4Z767_PAEAL Polyketide synthase subunit OS=Paenibacillus alvei DSM 29 GN=PAV_8c00070 PE=4 SV=1
HQYRTTHWIACPDFDKAVSVVKEDD--CILIMYREQLN-------SFLMLQMRQYFGE-R-MIAVELG-EACDFDTILS---SLAKKIKYIVHIASLMHE
EIQTVS-QLITEMELLFKSTFNLVKELLNVRHSINLV---IFTSNATKVEWIQPLSYGLSGMVNSIGREYANIKTRVIDIDNDT------SADVLIEDML
SNESLHAVSYRRNIKYMQQLHNVTQGTTLDDEQMTLIDNGVYIITGGLGGMGLAIAQHLFSLNPTIHVVLLNR-TYSRDTFSLEQVQSL----WAQGYSL
DIMQVDIANYVQMDDTLQQL-RDTHGAICGVIHAAGIAGDGFIMNKTWQTYESVLRPKIAGTWILHELTREDPLSFFVMCSSYASIFGAAGQSDYVAANA
FLDSFSYYRR-ALGLPSLTINWTGWRESGMAVTSGIRE--EGVYVRFLNDEEGATAFWHALKTKLPQVLIGIDSKAL-QM--EHDKP-----IISFANSS
NYKG---------N---------QSHRSKGTTPEDEIV-----------------VIG---KSMSDITDIERNVIYAWSQTLGTDQVDIHAKFFESGGNS
LLAAYLQKELDKFYPGIIVITDMFVYSTVVEIAQYIEKK-----------
>tr|A0A0A6PJ68|A0A0A6PJ68_9GAMM Uncharacterized protein (Fragment) OS=Candidatus Thiomargarita nelsonii GN=OT06_15295 PE=4 SV=1
DWLYTVAWQSKVEQLVSPQ-PDSWLILADQGGVGAKIAELLQARGHC----------------VQLYAKTSVDFEPILKTLFSLG-----IIHLWSLDVA
GSEELLSAIEQAQRLGCESVLHLVQTL-S-EVSPRLW---LVTQGAVPVSPLNVAQSPLWGLGKVIALEHPDWWGGMLDLAPEMPL---DAAKSLLTEIQ
NSQGEDQVAFRNGQRYVARLVRYRRPQIIQ--AMPLDADNTYLITGGLGALGLIFAQWMAARGAQHLALIGRSNASHAR----EILDQL----ARNGTKV
RVFQADVSCQVEMAKVLESI-KISMPPLRGIVHAAGILDDGVLVQQNWERFMRVMAPKVVGTWHLHTLTQDLPLDFFVCFSSSSTLMGATGQGNYVAANT
FMDALAHHRR-ARGLPSLSINWGVWADAGMAANLGSYDQFAEYGIGKIATKQGLQVFGELLEQNAVQVGVMVNWSKLLQQ--FSPNN-----EPPLSELV
NQIH---------QV--------TEQQPARQLEELQFK-----------------KASP-DERIARLTAYLQTQVANALRLN-TAQLDVQQPLNNIGVDS
LMAVELRNKVRKELGVDVPIVKFMEGASVVDLATQLSLQ-----------
>tr|A0A0D6YGX9|A0A0D6YGX9_MASLA Uncharacterized protein OS=Mastigocladus laminosus UU774 GN=SP67_20875 PE=4 SV=1
--------MNSVP--NFET-SNCWLIFVHSSTALNQLINLLKQAGRVITVELGDDYKRRSQDNFVINSSRKSDFQRLYREAFPTG-----VIFAWGNAPV
AEYA------DIVYKSSHAVLNLIQTITT-QKLPDLW---LVTRNANQITSIQPQQSCLWGLGAVINQEYPQMRCVCLDLSSTEEP---DEAEFLFQELH
TFSNELRLALRQGNRYGARLVSATIPPAQK--QQFVSKEGAYLITGGLGKLGLLLAQWLSKMGASHLVLCSRNIKS-LP----EAIASL----RQNGTQI
TVIGADITSAVDIQQIFSRF-GADLPPLRGVIHAAGILDDGLLSNQNWARYENVMRPKVEGTLLLDNYTRNLSLDFFITFSSAAVILGSPGQSSYAAANS
FMDALMQKRQ-SLGLPGISINWGAWDTEN------EIEKFASWGIQSMSSDLALKYLSELIMGNVSQGVIIINLSKFNQI--FTINQ-----L-FFAELL
IAKQ---------DI----------SNSAKLLEKL--------------------SIPI-DERAESLIQGIEQILREVTGLSANNFIPQQTSFLELGLNS
LMVLEFKNRLETNLACSLSASIIFDYPTLTSLSTYIREE-----------
>tr|A0A0E8NRH9|A0A0E8NRH9_MYCTX Phenolpthiocerol synthesis type-I polyketide synthase PPSA OS=Mycobacterium tuberculosis GN=ppsA_1 PE=4 SV=1
NFVHTIDWQPQTVDATHPGVPGPVAIIGDD---GAALCETLEGAGQ---------------------------------PAMSDGVQARYVVYVADSDPA
GADETV----DFAVRICTEITGLVRTLAEADKPAALW---ILTRGVHESAPSALRQSFLWGLAGVIAAEHPELWGGLVDLAINDDL---GEFGPALAELL
AKPSKSILVRRDGVVLAPALAPVRGEPARK--SLQCRPDAAYLITGGLGALGLLMADWLADRGAHRLVLTGRTPLPPRRDWQIDAIRAL----EMRGVTV
EAVAADVGCREDVQALLAARDRDGAAPIRGIIHAAGITNDQLVTSMTGDAVRQVMWPKIGGSQVLHDAFPPGSVDFFYLTASAAGIFGIPGQGSYAAANS
YLDALARARR-QQGCHTMSLDWVAWRGLGLAADAQLVSELARMGSRDITPSEAFTAWEFVDGYDVAQAVVVMPAPA------------------------
-------------GA--------GSGANAYLLPARNWS-----------------VMAA-TEVRSELEQGLRRIIAAELRVP-EKELDTDRPFAELGLNS
LMAMAIRREAEQFVGIELSATMLFNHPTVKSLASYLAKR-----------
>tr|S9T389|S9T389_PAEAL Beta-ketoacyl synthase (Fragment) OS=Paenibacillus alvei A6-6i-x GN=PAAL66ix_17562 PE=4 SV=1
RLLYQVEWMEQARSKNTKA-NEKMVLIGNDPDIIDRFHERLNGYGPSIRVIQSDKYVEHDDNIFFVAYTNKHDVKRLLENIR-YGKDTCKLIYISTADEA
KLNNLADQLKNTVEKECSGLLHLVQSITEYSNKMKIK---VITNNVHQIAATSLYQAPLWGFTEVIRLEHTLLWDGIIDTDTHMLK---NEIDDIINEIL
HGEEKQVVLGEQHKRYIPRLIRNSKSRANKELAIRIDDDAAYLITGGTGSIGQVYTEYLINRGAKNIILVSRSQASGKL---LETMNSW----KEKGVHI
TLEQADVSDEADVIAMVQKL-KQNNLTIKGVVHAAGIIDDKMIKDQTWNSFENAFKTKVWGSFHLHHALQDESLDFFVMMSSISSVVGNMGQANYAAANY
FMNRFAAYRR-SLGMPAMSICWGPWEEAGMATSNSNILKIENKGLYGMSKELGKKMIDKVFHKDLASIVVVANWELFSQR--TGVDE-----VTALSNFI
TDNH---------SR--------QGEQS-AAKEDVKLH-----------------ELSE-TERSEYLLSLLHKAAADIIGFQDINQLSVDSSFTEQGVDS
LMIFSLRNEIKALLDLQVDISVFFNYPSLRKLNGYLVTE-----------
>tr|Q2SW15|Q2SW15_BURTA Polyketide synthase OS=Burkholderia thailandensis (strain E264 / ATCC 700388 / DSM 13276 / CIP 106301) GN=BTH_I2363 PE=4 SV=1
GWLYAPRLRQSAPLERPIDTRRHWLVLLDEHGVGARVATRLREAAQVAEIAYADEMDA-----QAIDA-----------AAAAAADRPSSVIALWGLAAE
P----ARDDDSMLKRHYIRPARLLRAWADRTGDVDVTFVADGALAAQFGAPAAPEKAMLLGLARALPAEYPGWRARVADVDAA----AADLVECIVAEAC
ARSADDAAIHRHGSRWVETLEPIGAATTQ---AMAIRRDGVYLVTGGNSGMGRAIGRHLVE-RGARVVALSRRGG-------------------QSIPGL
TAIAVDVSDLDALRRAVAQIRAEHG-PINGVVHSAGMPPHALLRTAADTAMRDVLAGKFLGARNLRQVLCADSLDFVVLCSSLRAHVPAAGASDYMAANL
ALEALGASWA-ADGTRVRAIAWDTWTEIGMAT-VSDERFVPEDLTAGLSADEGVRVLEMASACE--------------------------SPRIAV---S
TRK---LDPLKARAREA---FSLARA-----------ADAHQPAAGSRHPRP-----VLAVPYVPARTALEARLATIWSDVLGFEPIGVIDDFFDLGGDS
VATLQIVARAKEQG-IHLDTHLAFGAHTIEELAAAG-VE-----------
>tr|V5IZL2|V5IZL2_9PSED Polyketide synthase SpiC2 OS=Pseudomonas sp. Q71576 GN=spiC2 PE=4 SV=1
DWLYTPRLRQSMPLEQLIDSQRNWLVLLDDHGVGQRIAAALRDAAQVVELVYTDDTVS-----DVIHT-----------QVEADWSRPLSVISLWSLAAQ
D----SSDDREVLQRHYLRPAQVLRAWADKAGDVDVTFVVNGAF---FGSPTAPEKAMLLGLARALRLEYPSWLARVMDVEML----AQDTVECILAEAT
ACSADDAVIHKYRSRWVETVEPVTISGGH---TLPIRRGGVYLVTGGNSGIGLAISRYLIDSWGAHVIALSRRGG-------------------QSGQGF
TAVAANLDNIDELRQVVVSIQAEHG-PINGLVHCAGMPPHALLRTATDAAVKEVFAGKFFGALNLQRVMLQMPLDFVVLSSSLRAHIPAAGSGDYMAANL
ALEALATSWA-ATGARVLSIAWDTWSKVGMAATASDARFVTDELAEGMSVEEGVKLFEAASQCG--------------------------LSRVVV---S
TRP---FSALKAHAQEA---FSVGRA-----------GEVAQRVSSTRHPRP-----ALNTVYIPARTALESQLAQIWSEILGYDTIGIKDDFFDLGGDS
VATLQIVARAREQG-LNLETSRAFEAHTIEEFAAATRIE-----------
>tr|W3V5C5|W3V5C5_PHOTE Putative polyketide synthase component OS=Photorhabdus temperata subsp. khanii NC19 GN=PTE_03088 PE=4 SV=1
PGLLVPFWRPVRLPGEK---------PYVVLLVDHSLAFFTSGLDKQIES-------------VSLNMLCPAQVRSALAGLSIGS-QKDSLVLSLAFPTD
G----FS----FSPTSLQILSELGKTLAEFSTSVHIYLITSYFSRTGRLTESVLTMAALKALALVMPQEIPGINCAFLCIQNP-------VLTGLLQTPL
H-----PLKLNDEGLFVEDFRCPDAEEVL---DEARFTGKTYVITGAGGRMAGAMAKVIARRFQGRLALISRQSADSPAMKR------LQEELKEAGAGV
EIFPYALESEADALASFESIRHRLG-DISVVIHAAGVTDGDSFSPLNADHYRAQLEPKARVAEVLAKVFESIPVEYCFVTSSMSTFFGGIAHAAYATANL
FLDSWGQIQN-RRPPRWVVVNWETVHFEADPRG----D------EVAFAGAEFPALFERSLREH--------------------------ENQKIF---S
AGQ---FMDRLYAWGGR---RTSSG-D---------RRAQLAGGVK-LKPRPE----TLTSVYQLPANDIQKEIVAIWSGILGVDGISIDDRFMELGGDS
LKTIVMAEKVYKKLGKRVSIQDFFVQPTIREIERQFLND-----------
>tr|Q2SGN4|Q2SGN4_HAHCH Polyketide synthase modules and related protein OS=Hahella chejuensis (strain KCTC 2396) GN=HCH_03442 PE=4 SV=1
AGMLTPFWKSIRLRKPSR----------RVLLAPASTEALTAGLTQDIEV-------------LDCNPLCSVQLRGALAELAAGA-RSEALTLTLAFPAD
G----LS----MNTESLQALADLGRALTDFSASVHIYLLAPSFLAVDQEADQVLTTAALKSLALVAPQEIPGIACACVEICNP-------ALASVLASPM
H-----PLKLSAEGLFVEDFRSPDEEEVL---DASHFTGGTFVITGAGGRMARAMAKTLAQRFQGRLALISRQSADSPAMQN------LRQELTAAGAGV
EVFPYALESESDALALFESIRQRLG-AIQVVIHAAGVTDGDSFAPLDADRYLAQLAPKARVAQTLARVFESAPVETCFVTSSMSAFFGGIAHAPYAAANL
FLDGWSQRRN-NRLTRWVTVNWETIHFEEASPK----D------ETALLGAEFPALFERSLRER--------------------------ENQKIF---S
AGQ---FSDRLYSWGGR---RPANGEGQ--------TS-SSVNSIK-LKPRPA----TVAAAFAAPGNALQEEIAAIWSGILGVEGVGVDDRFMELGGDS
LKTIVMAEKVYKKLGKRIAIQDFFAQPTIREIERQCLLE-----------
>tr|A0A0B6X7N4|A0A0B6X7N4_XENBV Putative polyketide synthase type I OS=Xenorhabdus bovienii GN=XBW1_2555 PE=4 SV=1
AGLLLPFWKPLRLPAEK---------PDAVLLIDSSLASLASGLDKQIEV-------------VSLDMLCPVQVRSALAKLSIGSLQKNSLVLSLAFPTE
G----FS----FAPASLQILSELGRSLAEFSTSVHIYLIAPACSMTGSLAESVLTAAALKALALVMPQEIPGVNCAFLGIQNP-------ALTRLLQTPL
H-----PLKLNDEGLFVEDFRCPDAEEVL---DASYFTGKTYVITGAGGRMAKAMAGVIARRFQGRLALISRQPADSPAMKR------LQEELKDAGAEV
EIFPYALESEADALALFESIRHRLG-EISVVLHAAGVTDGNSFSPLNADHYCAQLAPKAKVAAVLANVFESIPVEYCFVMSSMSAFFGGIAHAPYAAANL
FLDGWGQMQN-RRLTRWVAVNWETVHFDEDRRA----D------EVALSGAEFPALFERSLREH--------------------------ENQKIF---S
AGQ---FMDRLYAWGGR---GAANG-D---------HRPQAEGNVK-LKPRPK----TLTSVYQSPANEMQKEIAAIWSSILGIDGIGIDDRFMELGGDS
LKTIVMAEKVYKKLGKRVSIQDFFAQPTLREIERQLLND-----------
>tr|A0A0M0TCW6|A0A0M0TCW6_9ENTR Polyketide synthase OS=Xenorhabdus sp. GDc328 GN=AFK69_04015 PE=4 SV=1
DWFYQSVWQQDILRNK-NVKTALLFKLGDNSEQSTLYEQALINHHKIQ-VRLGQQCKLEISAPGTIRGLNSEDHANLFKFLNNNQMSIEDIIIDC----T
G----VNL---TVNEQLASVLYLLKSHRAFCNLKDITLLIQNAREVCNEPDIDPSAAAMLVISTIIRQEFHEVSCRAIDVGHV-----KDSAEILIREIE
A--GNKTVIYRNNRRWTETFLPSIPFMDE---TSRLKKEGVYLLIGGRGFIGHTFSQYLATEYNANLVISSRAKYEHDQK---------WQSVADAAKTL
EFVQADASDHDAMKKLIHDLVANYG-RIDGVFYLAGLSDDASFRSIDIGYIDSHLVPKQKGITVLEQVLEPVDYDFCLIVSSLAPILGGVGFFAYAAASA
YLDAFVLRHN-RRNKTWSLINWDGWELAE---KEKINA-VGSSLHLLVTRSEGVSLLEKVLGYE--------------------------EQALVI---S
TAD---INARIAQWSAP---AVHDNE--------------TAIQHGDYAARP-----DLDSEYVLPKSDIEKELVSVWQDFLGIEPIGLKDDFFELGGNS
LKAITLLSRIHKNCKIDVSLTHFFKNPTIEDIVILSASQ-----------
>tr|A0A077QGI7|A0A077QGI7_XENBV Polyketide synthase involved in xenocoumacin synthesis OS=Xenorhabdus bovienii str. Intermedium GN=xcnH PE=4 SV=1
DWLYQAAWQQHILRSE-CTKSALIFKLGSSNEQSTLFEKALLNHQKVR-VKVGSEFELEIEALSTLRCLNYDDYKNLFDLLNNNEISIEEMVIDC----I
N----VDL---SLNEQLAVVLYLLKSHRAFSPLMNVTLLTQNGVVVCNEPDINPFAAAMMSISTVIRQEFHELCCKVIDVGAL-----NDSADKLIREIA
E--DNKNVVYRNNRRWAEVFLPYSPIMDE---TSRLKKEGVYLLIGGRGFIGHTFAQYLATEYNANLIITSRSRQNIDDK---------WQQVSNDAANL
EFAQVDASDRVAMDAFIQDTTAKYG-RIDGVFYLAGLTGEASLRSIETDYIDSHLISKQKGIEVLEQVLEPVNYDFCLILSSLAPILGGLGFFAYAAASS
YLDAFVLRHN-RQNKKWTLINWDGWELAE---KTELNA-IGSSLHLLVTKEEGISLLEEVLKYE--------------------------KDAVVI---S
TAD---INARIAQWSNP---SLSKNE--------------EGSDDSGYSARP-----DLDSEYVAPNSEIEKKLVSIWQEFLRIESIGMKDDFFDLGGNS
LKAITLLSRIHKSCQIDVSLTHFFKNPTIKDIVALTDSQ-----------
>tr|N1NKU8|N1NKU8_XENNE Polyketide synthase involved in xenocoumacin synthesis OS=Xenorhabdus nematophila F1 GN=xcnH PE=4 SV=1
DWFYQSVWQQDVLKYK-HAKTALLFRLGERSEQSTLYEQGLIKHHKIQ-VNIGAQCELEVGILSTLRALHVEDYENLFKFLNKNEVPIEEIIIDC----T
G----GNL---AVNEQLASALYLIKSHRSFSNLTDITLLVQNAREVCNEPDIDPRAAAMLAVSTVIRQEFHEVNCRAIDVGNP-----DDSAEILMREIE
A--GNKTVIYRNNRRWTEAFLSYSPFMDN---ISCLKKEGVYLLIGGRGFIGHTFSQYLATEYHAHLVISSRSKYEYAGDQ-------QWQSVAEAAADL
EFVQVDASDRVAMEKLINDMMAKYG-CIDGIFYLAGLTDDASFRSIEMEYIDSHLVSKQKGIMVLEQVLEPVDYDFCLVISSLAPILGGVGFYAYAAASA
YLDAFVSQHN-RKSKTWALINWDGWELAE---KDKINE-VGSSLHLLVTKNEGTSLLEDVLKYE--------------------------RQAVVI---S
TAD---INARIAQWSAP---SVHDNE--------------AEMQHEDYSVRP-----DLDVEYVVPNSEIEAELVSIWQDFLRIKPIGLKDDFFELGGNS
LKAITLLSRIHKNCKIDVSLTHFFKNPTIEDIVMLCGSQ-----------
>tr|K9V185|K9V185_9CYAN 6-deoxyerythronolide-B synthase, Aspartate racemase OS=Calothrix sp. PCC 6303 GN=Cal6303_2599 PE=4 SV=1
DWFYLPVWKQSIPLEQETQQKLACLVFADKYEFADQFKQLLTQQEDIT-VEIGDEFCQLDRHRYVINPQRPEDYEVLLKDLQKRDFQPNTICHYWSIAPN
D----ILLKENYQYFGFYSLLYLAQAIGKQDNPCKLLVVTNNLYSVIGEEKLCPQKATILGACKVIPKEYGNINCSLVDLVIE----SVDVLNNLLAEIG
KIQNNQIVAYRGSYRWLQSFEPVALDDGS---KAKFKQGGVYLITGGLGGIGLVLAEHLAKTVQAKLILIGRGGLPERCQWEQYQKIQKMRSLEESGMQF
MVTSADVTDSQQMQAVVNQALQKFG-QINGVIHAAGVAGGG-VTQLTQEMVRNVLAAKVDGTLILDDICQQLNLDFFVVCSSKTAILGEFGQIDYCAANA
FLDAFATSRT-ASSGLTISISWDTWQEVGLAVETVLPDQKREEMKKGILPEEGIEVFNRVMGSN--------------------------LPHVVI---S
TQD---LPSLIQQSNAD---KYLEDALQ-------AGKLSSVNLSKAKHSRP-----NLGNTYVTPQTKVECILTDIWQEILGIDQIGIHDNFFELGGNS
INTIQIASNANKAG-LKLTTQQFFQHQTIAELATNLALE-----------
>tr|K9QFU2|K9QFU2_9NOSO 6-deoxyerythronolide-B synthase, Phenylalanine racemase (ATP-hydrolyzing) OS=Nostoc sp. PCC 7107 GN=Nos7107_3478 PE=4 SV=1
EWFYTPVWKQSRLLD-LSQKQLNCLVFVDKYGVGSEFSKQLAQQQDIT-VRLGEQFSQLDEKVYCINPQQPDDYDLLLKALQQRDFQLNTIAHFWSVTPK
Y----ISL-NEYDNLSFYSLLFLAQAIGKQDDSLKLMVVTSNLYDVTGEENLCPHKATVLGPCKVIPKEYRHINCSLVDLIIP----AAQNLDKLIAELT
LEQTNEIVAYRGSHRWVQTFDVVPLEDVS---KNKLRKGGIYLITGGLGGIGLVLAEHLAKTFQSKLILVSRKGLPERSQWEQWLQIQKVRSLEELGAEI
EVISADVTNLAQMQAVIAQALQKFG-QIHGVIHAAGVPGGG-VTQLTRDMADHVLAAKVQGTLILEEVLKDINLDFLVLCSSKTSILGEFGQIDYCAANA
FLDAYAYRNC-ISDRFTVSISWDTWQEVGFAVETVLPDQERAEIKKGILPSEGIEVFNRILASN--------------------------LPHVVV---S
TQD---LPELIKQNNSP---QYLQEQLQL-----LDSKLSSVNLAKAKHPRP-----NLGNDYIPPETEIEQILAEIWQEILGIEKIGIYDNFFELGGNS
INTIQIAAKANQAG-LQLTSQQFFHYQTIAELATDLAIT-----------
>tr|W1IR82|W1IR82_9ENTR Putative polyketide synthase type I OS=Xenorhabdus cabanillasii JM26 GN=XCR1_1390018 PE=4 SV=1
PGLLLPFWKPVRLPKEN---------LRAVLLLDHSLAELSNGWDTQVEM-------------TSLDMRCPMQIRNALTTLSGEQ-PANSLVLSLAFPPN
S----FS----FATDSLHILSEWGKALAEFSTSVHIYLVLPDT--VRYLVESSLTEAALKTLALVMPQEIPGITCAFLYLQNV----QHVSLTRLLQTSL
H-----PLKLNAEGLFVEDFRCPDVEEVV---DESHFMGKTYVITGAGGRMGKAMAQVIAQRFQGRLALVSRQSADTPAMQH------LQAELREAGASA
EIFPYALETEADALALFESIRQRLG-DIHTVIHAAGVTDGDSFSPLNAGHYHAQLKPKAQVAEILAKVFEHNPVEYCFVTSSMSAFFGGIAHAPYATANL
FLDGWARRQN-QRPPRWIVVNWETIHFDGEQRR---N-------EVALSATEFPALFERSLRER--------------------------ENQKIF---S
AGQ---FMDRLYAWGGR---RAANG-R---------SKPQTVNRIK-LKPRPN----TLTSVYQPAVSEMQKEIAAIWSHTLGVDNMGIDDKFMELGGDS
LKTIVMAEKVYKKLGKRISIQDFFAQPTIREIERQFSSE-----------
>tr|A0A068QX34|A0A068QX34_9ENTR Putative polyketide synthase type I OS=Xenorhabdus doucetiae GN=XDD1_2711 PE=4 SV=1
AGLLLPFWKPHRLPKETAEKTSHSLLLIDQLLLDRALASQARAWDSQIET-------------VKLNILCPKQVRNALVGLSPGL-HKNALVLSLAFPAD
G----FS----FAPDSLQTLSELGKVLAEFSNSVHIYLIASAV--IGDSAESVLTEAALKALALVLPQEIPGIDCAFLSLQEP----N--ALTRLLQTPL
H-----PLKLNSEGLFVEDFRCPDAEEVV---DESDFMGKTYVITGAGGRMAKAMAKVIAQRFQGRLALISRQSADSAAMQR------LLLELKEDGAGV
EIFPYALEREEAALALFESIRHRLG-DIHTVIHAAGVTEGDSFSPLNAEHYRAQLQPKAQVAAVLANVFESIPVEYCFMTSSMSVFFGGIAHAPYATANL
FLDGWGQRQN-RQPPRWIVVNWETVHFDEQSRP---TE------EVAFSAAEFPALFERSLRER--------------------------ENQKIF---S
AGQ---FMDRLYAWGGR---RIANGNGN--------SKRQVTNSIK-LKPRPE----TLPSVYQSPVNETQKEIAAIWSQILGIDGIGIDDKFMALGGDS
LKTIVMAEKVYKKLGKRIAIQDFFAQPTIREIERQFLHE-----------
>tr|I3TWS8|I3TWS8_TISMK DidE OS=Tistrella mobilis (strain KA081020-065) GN=didE PE=4 SV=1
DWFWLPVSREIPPPSAGAVITGPVLILADALGVSAILADRLRAAHGTL-VTPGSAFAAAGPDRFTLDPADPGQFRSLIAAL---DAEPRTILHAWALRGP
R----PPAAAAVQSRGLHALLHLLQALGSPGPERRLLVAADRL-LPVTDNDLRPDHAPLLGAAKIVSQEYDRILCRMVDPGTA----A--LADILLAELT
EAEAPRVTSWRGGRRFVGEEAPRRLTGDG---RARFVPGGVTVITGGLGGMGLAFAEEVAELAPGALVLIGRSVFPDPEDWEDWLSIRRLQAIIARGTRL
MVATADVADAGAVEAVLAEARRRFG-PITALLHTAALADYEGVIHGARARTDRVMAAKLQGTLVLDQATRNDPLTLFLLCSSLGTVLVKFGQVGYAAANE
FIDAFARARA-ADPGATVAIRWSDWRDSGMSVA-----IDESDYSDGLTDLEGRLAMRRAAGQA--------------------------APLIGV---S
QHD---LRMLVAQDPL---------R-----------AKAFLAETDRAHARP-----ALAQDYVAPRTAAEREVARIWQRLLGIDRVGALDDFYDLGGHS
LLATQVLSRITERLKVEVPLDAFLDDPTVEALAGLIDAA-----------
>tr|B1ZYL3|B1ZYL3_OPITP Erythronolide synthase OS=Opitutus terrae (strain DSM 11246 / PB90-1) GN=Oter_1966 PE=4 SV=1
DWFYVPGWRRGLAL-APPITGGEWALIPDASGLAERLAARLRGLAARI-GADPTKLL----------------------------------GARWIVSLR
D----VSAA--ASEPKLDELCALGRVLSSQAAETRLTVVATGLHAFPGENSAEPAKSLLLGAARVLPNEIAGMSVRVIDVARA----ELSLLDALIAEAR
G--EDEFVALRGRERWMQTLEPVRLEVGE---AKPCRPGAVVVITGGFGGLGLALAESLFERARARLVLVGRS--TAAAAAQ-----QRIDALIARGAEV
ITAVADVTDESALQRVHAQIRSRFG-GCQGVIHAAGVAGGG-ALARDPVAAAAVRAAKVAGTLVVDRVFGAEALDFFVLMSSLTAQLGEFGQADYAAANA
FLDAYATARR-REGVPMVAIGWDAWRDVGMAARFEPQGEL------RLTNAEGAEVLVRAVAAG--------------------------VPHVIV---S
TVD---LAWRRRQTRAP---KGTTSG-----------ATKDAVPARAAHPRP-----ALPVTFAPPQTATQRKIAAVWEELLGVAPVGVNDDFFALGGHS
LLASQAVARLRDAGVNGLTLATFFEAPTIVRLAATVAAD-----------
>tr|C7PT87|C7PT87_CHIPD Erythronolide synthase, Aspartate racemase OS=Chitinophaga pinensis (strain ATCC 43595 / DSM 2588 / NCIB 11800 / UQM 2034) GN=C
DWYYKLHWTPLAAKDSTSFKDRLLLVFTDNEGVSDALITLLEEKNRVR-VSPGNEFEMVSDKLFRVNYTEEKDYRLLSDSLHALY-VLDGIIYLSGFKPM
A----PAL-AAQLQTAFYGLFNACKTFSKYFKNFNLAVLTANVHAVVDDAQLSPVAALTPGMIKASLAEYYTLRTTCVDVDGE----KTTSIATLLWEEL
SDEVIRFVAYRNGKRYVQELNRVDEVQGN---PYQLEQQGVYLVTGGHSGIGYEMATALATRAKATLLIIGRRSAADVAGQ--------IAKLEQLGSKV
HYFTADISNESDMQTLFADIKKRFS-RLAGVIHSAGIGSSGVAIE-NIADVNNTFAPKVQGSILLEEHTRSLQPGFFVVFSSIGALVPASSSADYSAANI
FQDAFAAYWR-NKGRNFISINWPDWKETGLSYRKTLLQALRYSYLSPITSADGIEAFFSALSQR--------------------------QERFIV---V
KAD---FRNFIINPYFK---IGT---------------------IKKLQGEEQ----DTESKTANGFSPTELQLAGIWHEVLKLDQVRLEDDFYELGGHS
LNIIRMLNRIEQQMNVTLPIEELLRNSTLGGIAAHIDAI-----------
>tr|A0A022PJ48|A0A022PJ48_PHOLU Polyketide synthase family protein OS=Photorhabdus luminescens BA1 GN=BA1DRAFT_01894 PE=4 SV=1
DWFYQHGWKQQPLSTS-SDETTLLLRLGQPSAPTCCMESSLQRYKKIK-IHVGNEKVFDLDGENQIRLDNQEDFNQFFKLLEQSHVSVSNIVIDC----I
D----SAL---AVDELLSQILHLLKSYRAQTSLKNITLLVKYAVVVCNEKSIDPSSAAVMAISTVIRQEFPDLSCRAIDVGDM----ATDGATKLLAEIA
Y--GSETVAYRNNRRWCEDFVPYVSLARN---HVSLKKEGTYLLIGGAGFIGKTFSNYLAKEYQANLIITSRSSAYLDNS---------WQQIDKQASSL
QLIQADAKELDAMSELVQNVIKYHG-KIDGVFYLAGITGEASLRSIDKAYIQAHLEAKQKGIEVLEQALAEVDYDFCVVISSLAPILGGLGFYAYAAASA
YLDAFVIQHN-QYNNNWTLINWDGWEVAV---KSDINE-IGTSLHLLVTKEEGILLLADVLNYE--------------------------KDALII---S
TAD---INARIAQWSKP---NQLEEQG-------------HDNSNKEYSGRP-----DLECDFITAGNEIETQLIGIWEAFLRIKPLGIEDDFFDLGGNS
LKAITLLSQIHKSCNIDVPLTYFFKHPTVKEIAEFAGSQ-----------
>tr|Q09D72|Q09D72_STIAD Linear gramicidin synthetase subunit D OS=Stigmatella aurantiaca (strain DW4/3-1) GN=STAUR_0025 PE=4 SV=1
-WFFRKVWRPKEASPRAPVPGGACLLFLKGEGLGPLLREALLREGRCITVTPGPAFARTGPDAFCLAPADAEAYPRLLATLAEEGVRLAQVLHLWTADAQ
G----APPPAEVQREGVLSLLLLTQALTRQRTPLRLQVVSHHAQSTSPGEDVEPDKALMLGLIQTIPQEVPWLDARHLDLPRG---APEEEVPWVLRELE
ALPREREVAWRRGQRLVPRLEQVPPSALG-PRSPPFVSGGVYLLSGGLGSLAVELSRRLLKQFRARLLLLGRTPLEAPHAGRREAWKELVALAAKQGGAV
HYEAVDAGDAGALGDAVSRAEARWARPLDGILHLAGVLEERILAEETVEHFLSVLRPKVEGTRALEQLLGTRPGAFFVGFSSVNASFGGFSVAAYSAANR
FLEHFVEARRGAQGTRHFCFSWSQWEVTGLVLSETEERLANARGYQTLSLSRGWNSLLVALGHASGNLLVGLDARSLPIRVRMGVLARAVQPQAFVTGSP
GQDTGAGA--ALPE----VRDGL-GLRTPVLQRVERIPRTASGAVDTGALLALENGLPRAQERLALQGEAERKVAAIWKEALGVEEVGALDNFFELGGHS
LLLSQVRGRLAQDFGRPLPVLELFRYPTVRTLAAYLSG------------
>tr|A0A0A8UQW5|A0A0A8UQW5_LEGHA 6-deoxyerythronolide-B synthase OS=Legionella hackeliae GN=LHA_2073 PE=4 SV=1
-SLYKPVWSHQLANIDRKIREHTWIVFQDNTEIGNQLISLLRDYNKLFIVEPGKSYQLLDSNHFRISLKTKSDYLKLFEHLKT-ELKHPILFHTTSCNPL
FGKLSNEEIDTQLNASFYSLLFIAQAYREIDTPLRCGVLTQGTQRILGTELISPVNASLIGACRVISQEHPNIVCKVIDSNPVEFSSSKNTCLSLLNNDD
WLTQNILTAYRNGYQWDLSYTLAETTKIH----NRFRDKGIYLITGGLGGIGLAVSELITEEVNNPTLIFLSRTPMLPETKLYPKIKLL-NHLKQKGADL
YFYNVDIADSEALRETIQQCKTKFG-AINGLIHCAGVAGGGLVQLKTREIADTVFRPKIHGTFNLLKAFKDISLDFVVLMSSIAALTGEQGQIDYCAANA
CLDAFALSNA-FQSKFVISLNWNTWRDVGMAIETKLNWLD--RG-NDISPEQGKQVFLQALRTNF--------------------------TNLAVSNFD
-------IKS-YSKLV---MEKD----NV--------SGSPDIRASRTDL-------NIANNYQAPRNSIESQLAQLWQESLGIENIGTEDNFFDLGGHS
LKALKLIEKINRHFHRSLVINQLYQTPTIAELSDVISS------------
>tr|D5T6Q8|D5T6Q8_LEGP2 Polyketide synthase module OS=Legionella pneumophila serogroup 1 (strain 2300/99 Alcoy) GN=lpa_03123 PE=4 SV=1
-SLYKPLWSHEKIAVTANLKNFDYVIFKDKTGIGQKIINILKNHDEPIVVELSEEFRQLSKTHISINPGEKSDYNQFVSSLKN-TLRHPIIFHCFSCDSS
ESFLDTQQIENRLKLGFYSLLYLTQAFLNDNIPIRLAIITSGTQNVIGTEKISPINASLVGASRVIPQEHHNISCELFDINLYETTQNITNAIIIVSQAA
QDLPYQLTAYRNSYRWELSYSPNHNKTVL----QRLTDNGIYIITGGLGGIGLSLCHSILKNTKSPTFILCSRTPVIDESPHHHKVLQL-KKLKELGAAI
VCYQAHIGNDKDVDRFITFCKSRFK-TINGLIHAAGVAGGGLLQLKTKENADNILLPKIHGTYHLAKALREFHLDFVVFMSSIASITGERGQIDYCAANA
CLDTFANSNL-FYTQCLLSINWNTWRDVGMSVETQIDFFA--RG-NTISPLQGQELFLKALSSNC--------------------------SNLIVSNYN
-------IED-YSSLI---LDNN----P---------ADTEEHKVSRDTF-------SMSHEFCAPQGSIEKRLAKLWQDNLHIVDIGRNDDFFALGGHS
LKALHLIENINSILGVNLSIQHLYQAPTIAKLAELIYS------------
>tr|Q5WUR2|Q5WUR2_LEGPL Uncharacterized protein OS=Legionella pneumophila (strain Lens) GN=lpl2106 PE=4 SV=1
-SFYKPVWSHEKIAVIAHLKNFDYVIFKDKSGIGQNIINILKNHDEPIIIEPGQEFRRLSKTHININPGEKSDYNQFVSVLKN-TLRNPIIFHCFSCDSS
EDFLDAQQIENGLNLGFYSLLYLTQAFLNDNMPIHLAIITTGTQNVIGAEKISPINASLVGASRVIPLEHHNISCALFDIHLYETTQNITNVVIIVNQVV
KDLPCQLTAYRNGYRWELSYSSNHSKTVL----QRLTDNGIYLVTGGLGGIGLSLCHSILKNTKHPTFILCSRKPVIDESPYHHKALQL-QKLKINGATV
VCYQANIGNDKDVDRLITFCKSRFK-TINGLIHAAGVAGGGLLQLKTKASADNILLPKIHGTYYLAKALRQFHLDFVVFMSSIASITGERGQIDYCAANA
CLDAFANSNL-FHTQCLLSINWNTWCDIGMSVETQIDFFA--RG-NTISPLQGQELFLKALSSNC--------------------------SNLIVSNYN
-------IED-YSSLI---LDNN----P---------ADTEEHKVSRDTF-------SMSHEFCAPQGSIEKRLAKLWQGNLHIVDIGRNDDFFALGGHS
LKALHLIENINSILGVNLSIQHLYQAPTIAKLAELICS------------
>tr|D3HN57|D3HN57_LEGLN Putative polyketide synthase OS=Legionella longbeachae serogroup 1 (strain NSW150) GN=LLO_3443 PE=4 SV=1
-VLYSPVWTRGALSVNTKISDYQWVVFKDSMDIGQQIINVLSFYNRPIIIESGDEFIIHSQSHFTINPVVKEHYIDCFKCLRE-TLNHPKLIHCWSLDEN
QGLDDDATIEASFDKGFYSLMYVIQSFVEVKNELGFCIITRGTQHILGTERLSPANATLSSFCRVVPLEHPLIRCLMADIDRDVKGVELTAIFAILADKS
---RDILVAYRNNYRWLPAYVAIENNSLK----TRLSDNGIYLITGGLGGVGLALSEAIASQVCQPVLILSSRKPYPPQEEDHDTVSRL-KYIQSLGASI
NLYPCDVTNDQDVSQLLHWIFLKYG-KLNGLIHAAGRAGNGVLQLKTHEKAYQVLSTKIYGAYYLAKATQKLILDFVVLMSSIAAVVGAKGQIDYSAANA
SLDAMAQSNL-FHSKFTLSLNWNTWRDVGMSVHSSLNLLN--LG-NDISSKEGQSLFLNALSTSY--------------------------RQLVISNYE
-------LDR-YQALL---ANTV----NE--------KEETKNKVSRKHL-------NIKNTYSEPQDELEKQLAKLWQECLHIDSIGREDNFFALGGHS
LKAMTLIEQMNTLFNCSLSIQHMYKAPTIALLRQLISE------------
>tr|A0A098G7E3|A0A098G7E3_9GAMM Polyketide synthase module OS=Legionella fallonii LLAP-10 GN=LFA_3028 PE=4 SV=1
-ALYKPVWSYEAIEHPSHLNEFNYILFKDKTGIGEQIAEILIKQGKPIVIEQGQEFKQLSPTHFTINVSEPSHYTQLMSSLKD-TLHHPIILHCFSYDDV
QEFLDTAQIEHRLHLGFYSLLYMTQSLLSETIPIHVALITSGTQRIVGTENICPINASLLGSSRVIPLEHHNISCEFIDINTKDNVALI---LNLLNQKQ
KEKSHKVTAYRNGYRWELSYAPFQSKTPS----NRFSDHGIYLITGGLGGIGLALSNAIARHAVSPTLILCSRKAIPPQSPYHTKIEQL-HQLKELGANI
ECFQADIGNYEEVVDVVTFCKNNFG-RINGVIHAAGIAGGGLIQLKTKEAVHQVLVSKIHGTYHLAKALQEFNLDFVVLMSSIASITGEQGQMDYCAANA
CLDSFAQSHL-FHTSCLLNINWNTWREVGMSVETNMSLFS--RG-NTISPTQGQELFLKALASRC--------------------------SNLVTSNYS
-------VEE-YDQLI---RDNK----P---------IIDEEHKVSRDTF-------HMNQEFKAPKGPIEKQLATLWQENLHIVAIGREDDFFALGGHS
LKALTLIEHINTTLGTHLSIQHLYQAPTIAQLAEVIGA------------
>tr|G8NU16|G8NU16_GRAMM Long-chain-fatty-acid--CoA ligase., 6-deoxyerythronolide-B synthase OS=Granulicella mallensis (strain ATCC BAA-1857 / DSM 23137
-VLYRRHWELLKSTPGRSASVGHWLILADSGGVGAQLAELSRKGNCSLISEVEVE--KLS-----LNDQTL---------------QG--VVHLGSLDLE
PDMAG----RSKVSSS---VLALVRMLKGNGSKTHLWLVTAGAMPILEQDVPAVSQAALWGLGQAIEAEHPELWGGLLDVDPARPSA----CLLAIE---
---GEARLALRDGQRYAAKILHDHQPMES----NLFEENATYLITGGVGGLGTRLTKWLLER-AGNVALLGR----------------T-VPQQSVNEKT
RFFRCDLANTDETMAVVREIENSMP-PLKGIFHLAGTLDDGLLLAQDGERFYRSGAGKAEGAWNLHLASRDIALDHFVLFSSMASLVTLPGQGSYAAANF
VLDTLAHHRR-ATGKPALSVNWGPWADLGMAATEYVERMSS-FG-VAALPADALTMLGQLMSSGAIQI---------------------GVTQLASAKLS
-------RKS-VSAIT---SSQL----A-GL-----PTERHEGLDRDTEF-------VIALRSCASVDWLAARLLEIFSETLRVEAITSTQSFLEMGGDS
ILALELTNRLSSTLGRTLPGTLLFTFPTIAALTDHLLR------------
>tr|A0A081PA50|A0A081PA50_9BACL Uncharacterized protein OS=Paenibacillus sp. MSt1 GN=ET33_12790 PE=4 SV=1
-WLYEPVFRPTTAITWPKECSGLWVVFEEERGGWMDVLERLEHASPVVRIREASGFEQLSERVYGLNPARLEQYALLFDALAA-GEGPMRVLCSWAEPDS
PGGV----------SGFLQLSRALQAHAGEGNSAHLCIVAEGLYNIAGETDIRPERMTVAGLGQVWMQEHALAAFHLADALMPSRRSQADAILEFMS---
---AGSPRIYRGNQRWMLEYEPVHAKRPE----EEAQAAGTYLLIGPFDRKMQAFAQYLVQPGLTRIVIINEQPVMPDKAAARQAAAHA-LRLEELGAEV
HFVPIAFPKQRALAEAVDQAAALYG-EVTGVLYTDWSSEEMTFTAADGQAVEAELDRTAQGLDELARALAPHRPDFCLIQSSIASELGGLGLSLHAAAAA
YTEAFVRRHE-LTDSRWRCIQWDAWTSGPVSSDREVSELA---R-LAIRPEEGVRLWTKLMACDTI-------------------------SQCLVSTAD
-------FAA-RRAYA---LQSQ----NRQAE---QTGPGKGNLALRPRP-------ALTVPLVTPRHDMEQQLADAWSELLGMEPIGIHDDFFNLGGHS
LLATQVISWVNSHFPIEFPLKLFFEYPTVAEVAEAIEA------------
>tr|V3T1K6|V3T1K6_9ENTR Beta-ketoacyl-acyl-carrier-protein synthase I, 6-deoxyerythronolide-B synthase OS=Serratia sp. ATCC 39006 GN=Ser39006_03352 PE=
QWFYRPTWRPLALADGTPPPAGCILVFMDDIGVASECSILSAQGHTPIAVAKSSSFRQFGERSFAINPACLQDYLDLFSALRGRLGEDLQLYHFFSLGKP
EDPLDADDIAPMMSVGFYSLLHIANALAE--TTNTLSVISNHLYQIAAEQHTAGAKGALQAACLVIPQEHPHIQCHSIDVMVPDHPRQSRLIQQLCFLMA
KSSRPAAAILRDNSLWGRSYERLAANAAQ-TAATPIRKRGVYLITGGFGSIGRLLASHLATQYQASVILSTRGMDDN--TEGREKHQWLQTL-RASGAQV
EIICADVTDYHAMEKGLA-VAEEICGAVNGVIHCAGLVGQMYLKPTAPTDCEEIFSAKITGVQVLAALFEGKKDFCLCMSSISSVL-GGLGHAAYIAANI
YMDYFVQQQNL-----TADFRWLSVNWDGWQTERMQAQRITQDKF-AMSPAEGIAACEWALAQNETDLL-------------VHSTA----------DLD
ARIKQWVTLDSLQ---DQPR-------SVFPRPQ----------LDTPY--------------VAPEDTLQQALCTMMQERLGVDKIGINDDFFQLNMDS
FIIVQITNMIKKQLNVDIPVVTFYKYPNINVLSAIIQQLGY---------
>tr|D3HQ94|D3HQ94_LEGLN Putative polyketide synthase of type I OS=Legionella longbeachae serogroup 1 (strain NSW150) GN=LLO_0722 PE=4 SV=1
QHLYHIRWNTLKFNA--TEIPEL-LVIASDPVYAKKLV--------------DLNYQFIDN--------------------------------------L
NEIIENKNIVLYHQDQFNALFHCCQKLFK--LRPSFILVTENAYAIHDKDKVNPYHTMASSFWKSFSNELELSKNYIVDLDAKS-----NLSTILSILYS
TSNSENQFAVRDSI-YIPRLKKMQLPT-------SFKSDASYLITGGTGGLARLLMEYLMQRGAQHIIITSRSECNPIM----NRAR-------KKNIFI
HHYQADASNYQQMATIIA-EIEQGSYPLQGVFHLAGRVQDGLLINLSDEEMQPVLSAKMDSALILHQLTQEIPDFFVLFSSSASLL-GARGQANYVAANG
FLDGLAYLRQQQG-LPAIAINWGPFNAIGMTANLSQAIQ--QRGF-TSLEKSSIDILDVLLKSQLAQIA-------------VCPINWEI-----YFKFL
PKQ-AWLADL------------------VKNNPV-----------DQHFLNALR-----QHTQEESMALLGQALREIVADVLALDQIKIDDGLFSLGLDS
LMAIEIRNRIHDKLQCPTNLSYFINKPTIRKIAKSIVDELQ---------
>tr|W0BHC0|W0BHC0_9GAMM KR domain/condensation domain/beta-ketoacyl synthase, N-terminal domain/beta-ketoacyl synthase, C-terminal domain/phosphopantet
QQLYQIQWDPFKLNA--AFVPEL-LVIAKDPEKAKTLA--------------GLPYQCVSN--------------------------------------L
DEVVEDKNIVLYEQTQFNELFHCCQTLFK--SKPCFILVTEQAYAVNDKDKVNPYHTMASAFWKSFSNEFEFPHNYTVDLGVKN-----TLSEILKYLFT
ANYSENQFAVRDSI-YIPRLRKTPLPA-------LFKSDASYLITGGTGGIAKVLITYLMQRGAKHIALISRSGGGDIL----ETAR-------KEQVFI
KHYQADASNYQQMEKIIA-DIEQGSKPLQGVFHLAGVVQDGLLINLSDEAIQTVLSAKMDSALILHQLTQMIPDMFVLFSSSASIL-GARGQANYVAANG
FLDGLAHLRRQQG-LPAIAINWGPFQAMGMTAHLTQALE--HHGF-TLLDKEGIELLDVLLRSQLPQIA-------------VCPVNWEL-----YCKYS
PKQ-PWFSEL------------------IKNRPA----------TNQHFLNALR-----QQPTEAYIPRLSQALREITAEVLALDQINVDDGLFSLGLDS
LMAIEIRNRIHDKLQCPATLSYFINEPSIGKIAKNIADELH---------
>tr|K2KT85|K2KT85_9GAMM Beta-ketoacyl synthase OS=Idiomarina xiamenensis 10-D-4 GN=A10D4_11184 PE=4 SV=1
YCVSTPVWQQSNLV-TQITEQLRWIVLGKELSLCQRLEQLSVKGIEPICVVEGEQTEATDDNHWIVNPNQPHALEALIKEAE-LGLQSVRVLNLWPLAVT
LDDTAKKRLL-----RVREALDASQALES--VFVQLLRVTQGAQSVTGEEELYAEQALLS-IELALNDSEKQKQWRTLDVMLPAPQSALTLAEQLVSEMG
ASSEQSCLALRGKHRWVKSVDTINLELGS-QDYLNDVKGRTFALVDGVNDLGLTIAYQLACAGAANIIVATNETLDRSTDVLAQKIWQLKVI-EDNGCSV
QLIVEDSKTELGAAAIYQ-HAKASDSPLHSVLLMT----QGHIQSC--LESITALS-KVTQDSGADERFNVEPEHRLLLQSYQNALAGT----AACAAK-
-----------VS-SIICHIGKGNLQWEEA-----------------------SAAVLRIMSAHLNVAY-------------YTANS-------------
---SVETETESYA---AALS-------SRYQRPE----------LENEY--------------RAPETQLQKQLAGIWTDLLCIDAIGIDDNFFELGGHS
LLATRLFARINRDFGLSLQLRNIFESSTIAEQADLIEVLLQ---------
>tr|A9AV09|A9AV09_HERA2 Beta-ketoacyl synthase OS=Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785) GN=Haur_3965 PE=4 SV=1
DWLAAPSWKRSIQAAARLAEPHCWLMLADE-GLAAETAWLEQRGQTVITVMPGASFAALGQARYMLRPTSREDFTALLQTLERQGHAPSRVVHCWLFGAQ
EDALSDATLTATLDVGFYSLLALAQALGD--QGV-INAVTAAMQEVTGQENLQVAASTVIGPCKIIPQEYPNLTARSIDILLPAGA-ATALVAQLGTELA
TPPTGDQVAFRGAHRWVQVFEPITVPAAP-ASHPRLRTGGVYLLTGGLGGIALGLARDLAATLQAKLVLVNRSGLDRAEQGVGRRIQQVLDL-EVLGAEV
LVIQADVTDTVAMARAVA-EAQARFGTIHGVLHTAGVPGVGLMQLKDAATAAAELAPKVQGTLALTS--AGIPDFLVLFSSVTSATGGGPGQVAYCAANA
FLDAYARKHATDH-GQTVAVSWGEWLWDAWSEGL-QGFAAYRTTF-GITFDEGADILRRILAEPLAHVF-------------VTSEDLLP-----MAERS
RRESRGLEELQRQ---QEAR-------PTYPRPE----------VGTSF--------------VEPQSVIEQQIAGIWSTVLGIAPIGLHDNFFDLGGNS
LLGLDLFSRIRKALKVDKPAYVLYEAPTVATQAAYLTPAPE---------
>tr|C7Q561|C7Q561_CATAD Beta-ketoacyl synthase OS=Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897) GN=Caci_7000 PE=
QWLHLPVWRQTAAP-AAVDLPESWLVFSRD-GVADRVERLRGSGAAVTVVRPGAAYA---EGDYAIRPGNLDDTRQLLRDLRVAGGVPSRVVHLWALGSS
DPV----------VDGLHTLVALARAAGE--VGV-LDVVTAGAQQVLPGDATDPLAATLTGPALVVPVEYPSVTARLIDLDAQP----PKTVAALTAELA
RPAADRIVALRHGRRWVCGFETMPEEALP-SAAPILRESGVYLITGGLGGIALGMAERLAAECHAKLVLFGRTGLPRETDETRERVRKVQAL-LDLGADV
EIVVGDLGRPEDVRRAVT-TALDRFGALHGVLHAAGLPGMGLMQFKEPGELDTVLAPKVAGTLALAE--EEIPDFLVLFSSITSATGGGPGQVDYCSANA
FLDAFAAQQSAAG-RPVVSVDWGEWLWNAWSAGL-DGYAENRTRI-GIGFDEGWRCLLRALASGEPRVV-------------VSTQDFGS-----LVRLS
AEFTD-AVAATAA---LDGG-------ALHPRPE----------LMTPF--------------QEPEGATEETIARMWRESLRLDGVGALDNFFELGGNS
LLGVTIVTALRKEFGLDDPPHTLYEAPTVAALAEVVDKARS---------
>tr|A0A089NFM6|A0A089NFM6_9BACL Polyketide synthase OS=Paenibacillus graminis GN=PGRAT_09285 PE=4 SV=1
KWLHEWKWRPEPLAEDNSLAAGAVLVWKGETEFGRELESVLDTERNPVYVSFGDEPHYDGDRSFTIRMDREEDYSAMLRQLPG---AVSAVIHLSNYARE
KLRT-PELLTQAVNDGIWSLYFLGQTLVLQGRDVRLIIVTNKAFRLEGDQEPAQTAAAAVGQVI--DLEHEGIHVSVLDMNKDEYLTGQEFAAALNASLK
LRNDGEVTAIRSGTAYLRTLERMPEQVAG--EGFEPYSGETYLITGGTGLVGSRIAEALVRQAQINLVITGRRPVPAEPG----RLLELEK----LGAQV
MYAAVDVTSRTQMEELLDRIHAVYG-PLHGVIHAAGRMEYAKLLARSQDEIEQVLAPKWQGTIITDLVTRQEPLRFFAALSSVSASAWASGLGDYAAANA
FLNGYCIFRA-GDPGRSLSINYSLWKDTGAGTDKLVDLALKGQGLQPLAHEEAAAAFLRALSSTGSDVHV-LDLVEPEYSALPSRQQEPMRVAERPFTHR
--STREIRDIVYQAIGEELR-------------------------------------------------------------ISIRNLDAGMNFTELGLDS
VGATRVVADIGGKLNTELYPTLIFEYQTPEALASHIAEQ-----------
>tr|X4ZXT0|X4ZXT0_9BACL Beta-ketoacyl synthase OS=Paenibacillus sabinae T27 GN=PSAB_07810 PE=4 SV=1
GLFHEWQWKPADLTGGTLFNEGALIVWNGNLEIGGELERLTDTERNPVYAASGDKFHFDGKRSFTIRPDHAEDYADLLEQVPG---RLSAVIHLSHYLQE
ELHA-ENLLKG-VNEHFYSLLYLGQGLVRHGSDVQLVIVTDKAYALPDDAGPNQAAAATLGQVI--GTENDGIRVSIVDMNKQEYPSGRELAKALTLAIQ
QQADEEISAIRGGVRYERTLEKMPAPAVG--QAINLNDGETYLITGGTGLVGGQIALALARQARINVVLTGRKQLPPDHP----LLPKLEE----LGAQV
MYAAVDVTDQAQMEELLRSIHAAYG-PLHGVVHAAGQLEYTKILSRSVNDMDSILAPKWKGTIITDLVTRQEPLRFFAALSSVSATAWASGLGDYAAANA
FLNSYSSYRT-KVPGRSLSVNFSLWSDTGAGTENLLELTLRSQGLKPLAHSRAADAFLRALGTARPDIHI-LDLVKTERPAALKAERHPAAAAARTQVYH
--TAKEIRETVYRTIAGQLQ-------------------------------------------------------------IPVSHLEAGKNFMELGLDS
LGAVQVVSKLGGIFNTELYPTLIFEYQTPEELSAHIVEL-----------
>tr|A0A089ISP4|A0A089ISP4_PAEDU Polyketide synthase OS=Paenibacillus durus GN=PDUR_08950 PE=4 SV=1
SLFHEWVWKSEPFADDYRLPEGAVLVWNVSPDIGRELESLLDPERNPVYLSFGDKLQYDGERSFTVRVDQAEDYSALLQQVPG---NLAAVIHLSNYSQD
KLPA-SALLNSVLNESFYSLFHLSQAIVRHESNVQLVIVTNKAFMLEGDQGPVQAAAVTLGQVI--DLENEGIRVSAIDMDRDEYPSDRDFAAALSNAMK
QQTDTEIAAIRSGARYVRALEKMSVQADR--ESIELHDGETYLITGGTGLVGGRIAAALARQARINVVLTGRRKLPPDNG----LIPELEE----LGAQV
IYAAVDVTDQAQMEDLLRKIHDAYG-PLHGVIHAAGQLEYAKLLTRSLGDIDNMLAPKLNGTVITDLVTRQEPLRFFVTLSSVSASAWASGLGDYAAANA
FLNGYSCYRA-NDPGRSLSINYSLWKDTGAGTEDLLQLTLKAQGLKPLAHEEAAAAFLRALASTGPDIHI-LDLLKAESFTAPRTERTTVAV-RQASVYR
--SAREIREIVYQAIAEQLQ-------------------------------------------------------------ISVRSLEVGMNFMELGLDS
VGATKVIAELGSRLNTELYPTLIFEYQTPEALSAHIEEI-----------
>tr|A0A0F7CGZ1|A0A0F7CGZ1_PAEDU Polyketide synthase OS=Paenibacillus durus ATCC 35681 GN=VK70_04635 PE=4 SV=1
GLFHEWQWKPAALESNTKINEGAVLVWNGNLEIGGELERLMDAERNPVYVASGDKFHFDGKRSFTLRSGNAEDYADLLEQLPS---KLSVVIHLSNYLQD
ELQT-ENLLNS-INENFYSLLHFGQGIVRHGSQVHLVVVTNKAYNLLADAGPNQAAVATLCQVI--DLENDGIQVSVIDMNKEEYSSDRDFVKALTTAMK
QKADEEIAAIRGGVRYVRTLEKMPAPAVG--KGIELHDGETYLITGGTGLVGGQIALALARQARINVVLTGRRQLPPDHR----LLPKLEE----LGAQV
MYAAVDVTDQAQMEELLRKIHASYG-ALHGVVHAAGQLEYTKLLSRSVSDIDSVLAPKWKGTIITDLVTRKEPLRFFATLSSVSATAWASGLGDYAAANA
FLNGYSSYRT-KEPGRSLSVNFSLWSDTGAGTEDILELTLRSQGLKPLVHSKAADAFLRALGTARPDIHI-LDRIKSERSTVLNAERQPAAS-SHSLVYR
--SAKEIREMVYRTIAEQLQ-------------------------------------------------------------IPVSHLETGRNFMELGLDS
LGAVQVVSKLGSLFNTELYPTLIFEYQTPEELSAHIEEV-----------
>tr|M1MZ76|M1MZ76_9CLOT Polyketide synthase modules OS=Clostridium saccharoperbutylacetonicum N1-4(HMT) GN=Cspa_c29360 PE=4 SV=1
EWFYNWKWAPGFQEAFSSLQAGNVVIFDDGSGINEEVEKLLDPDKNKVSIRAGETYSYDGDRKFVVNPLIESEYVEVFNAIPG---SIATVIHLWNLKQE
ISNL--EAVFRVINGNLYSVLYIGKALSRLNEGIKLLLATNLGVPIDEKHKPHQSIAITLTLAL--DQENSFINAHCVDLDKNEFESNREIAKVLFNEIM
SETNSEIVVIRDGVRYIRDLINVIELNET--SEIKFKDGETYLITGGLSAVGGAIAKAIVKKAKVNLVLTGRKELPLREE----LILELEE----FGASV
SYEVVDVTKMDDMKALMIRINNRYG-SIHGVIHAAGTVDSSKLLNKEIQVVNDVIEPKLQGAVITDLVTRKEPLKFFVMISSVSCSIWSAGLGDYSAANS
FLSAYSFYRA-GQPGKSIAINYSLWASIGMGADEGADLALKAQGLNPLAPKKAVEAFMRVLSDGNQSVHI-IDKIENEASK------------AVKFNFK
--KVNNVKEVVYSVIAEQLH-------------------------------------------------------------IEKDHLDIGQNFLELGLDS
LGAIKVMETLGNKLGMELYPTLIFEYQTPETLAEYIEKV-----------
>tr|A0A0E4H8A7|A0A0E4H8A7_9BACL Beta-ketoacyl synthase OS=Paenibacillus riograndensis SBR5 GN=PRIO_1961 PE=4 SV=1
KWLYEWKWRPEPLAEDNSLAAGAVLVWKGETEFGKELESLLDPERNPVYISFGNEPHYDGDRSFTIRMDREEDYSTMLRQLPG---AVSAVIHLSNYARE
KLGT-AELLTQALNDGIWSLYFLGQALVLQGSDVRLVIVTNKAFRLEGDLEPAQAAAAAVGQVI--DLEHEGIHVSVLDMNKEDYPSGREFAAALHTSLL
LRADGEVTAIRSGTAYSRSLERMPEQAAG--EVFEPCSGETYLITGGTGLVGSRIAEALARQARINLVITGRKPVPANPE----LLLELEK----LGAQV
MYAAVDVTSRAQMEELLARIHDVYG-PLHGVIHAAGQMEYAKLLTRSQDEIEQVLAPKWQGTIIADLVTRQEPLRFFAALSSVSASAWASGLGDYAAANA
FLNGYCIYRA-GDPGRSLSINYSLWKDTGAGTDRLVELALKGQGLQPLAHEAAAAVFLRALSSPGSDVHV-LDLVEPEAFALPPSRQEPARLAEQKFIHR
--SAREIRDIVYQAIGEELR-------------------------------------------------------------ISVRHLETGMNFTELGLDS
VGATRVVADIGGKLGTELYPTLIFEYQTPEALASHIAEQ-----------
>tr|A0A0M2JC79|A0A0M2JC79_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces mangrovisoli GN=WN71_31690 PE=4 SV=1
P------WLADHLIMDSVIMPGAAFVEADLAGCDHEMEPLVLPERGGIVQTTVGEPDESGRRPLTVHSRPEDDTEAPFVHVSG---TLATARTAAPYDFT
EWTP-VEAAPGGDGEA-WAVLGLALWLADDR-DARLVLVTRGALPLDGR--PDPAAAAVWGLVRSAESENPGRFV-LVDVDPA--AAWPTVTGALRRA--
VATEEPLALYDGEIRAARLTALPPTETGA--EPASWSADGTVLVTGGTGGLGALVARHLATVHGVRHLLTSRRGPDAP-E----LAAELGE----LGARA
TIAACDVADRAALADLLAGIDPAH--PLTAVVHTAGTVADG--PSLTPDHLDDVLRPKLDGALNLHELTAEHDLDAFVLFSSAATVFGSPGQANYAAANA
FLDALAHQRR-AAGLPAVSLAWGVWAESGGMAREGDLKRLARAGAAAMTAAQGLALFDAAVTAAGAEVPMRSGELPPSLVRVPR-RRSAAAEAGSPLTDL
--DAKELLDLVRGHAATVGH-------------------------------------------------------------GSGSSLAAQRTFKELGFDS
LTAVELRNRLTTATGLRLPATLIFNYPTPTALAAHLHTE-----------
>tr|A0A060LNM6|A0A060LNM6_9BACI Uncharacterized protein OS=Bacillus lehensis G1 GN=BleG1_0358 PE=4 SV=1
RWFHEWQWVEDLGKAYQPDRNGVTLVVSSESDCHRSIAYLRETGEDLIRVENGSTFNQKDSYCFTVNPSKASDWEHLKSVLPS---DIKNVVFLSYGSQK
VGDE--K-----YIESWKDFLTLASFTSMQSNQMRILVVTKQLHPLMKTDSPYQALDATFANVL--DTEAHVYAS-TIDVEED------DCGVVIEEELK
RFPPEEVALIRKGKRYVRALTQNRQMSFE--DEINIEENDTYVFTGGAGSIGSEIALELASKAPINLVITGLTPLEESEQ----LFSRLKS----LGARV
SYFAVDVGNRQEMDRVLTEVRTLYG-RVDGVIHGAGLLSPESLMKRDQESVKAVLNPKINGTRVLDELTRNDSLKFFVMLSSISASIWSAGLGDYAAANA
FLDQYSYYRT-TKPGKTIAINYSLWEKEGIARSSLSTFIKKTQGLESVSSSLGSKVFFQALNANGEPLHV-LKEKTNSPM-----KREPIEKAKQQNVTL
--EKGAIRNLVYQITADQLQ-------------------------------------------------------------CPVDELETNRNFEELGIDS
IRAVTVLDQIAQSLKLELNPTLLFEYQTPYELSKYLEDV-----------
>tr|B9E1U5|B9E1U5_CLOK1 Uncharacterized protein OS=Clostridium kluyveri (strain NBRC 12016) GN=CKR_1419 PE=4 SV=1
SWFYSWNWKAELDNSLSSLPAGSVVIFDDGNGIGEEFKSMFDEKENKIVVSLGSEYSWDSNKNFIINPLVEKDYIELFKNIPE---PIAAVIHLWNLKRE
AWKS--EFVFRVIQEDIYSILCIGKALKELNENIRLLLATNSGISVTENYKPHQSITVTLALAL--DQENTFINSCCIDIDKKEYKSNKELAEILFNEIG
KEINDEILVIRGGIRYVRDLINTGELNKY--SKIQFNDGETYLITGGASAVGGEIAKAFAKKAKVNLVLTGREKLPLIEE----LILSLEK----LGANV
TYEAVDVTKINEMEVLMEKVNNIYG-SIQGVIHAAGTWDFSKLLDKSIDTVNSVIEPKVQGAVITDYVTRKEPLKFFVMLSSVSSSIWSAGLGDYAAANS
FLSTYSFHRA-SEPGKTIALNYSLWAKTGMGANNMASMAVKVQGLNPLPAEKAVEALMRVLSDGSQRIHI-LDKLEIKPLS------------VNTLDFK
--KSQNIRETVCKIIADQLQ-------------------------------------------------------------VHQEELDIGQNFLELGLDS
LGAVKVMEKLGHNLGIELYPTLIFEYQTPDSLAQYIEKV-----------
>tr|A7GTF8|A7GTF8_BACCN Beta-ketoacyl synthase OS=Bacillus cytotoxicus (strain DSM 22905 / CIP 110041 / 391-98 / NVH 391-98) GN=Bcer98_3193 PE=4 SV=1
DWLYEWKWEMETPLYIENDKRGSILVFDDEQQVGKEVCGILEQINTSVVVIPGNEFHYDGDTRFTIRPESIEDYMMMLQHIQG---DSISIIHLWNGTKE
SVTP-TLFLQSALFQTSYSIILMAKALKIKAKNVEFIVVTDRAFAVLQDEEPQQSISAVIGQVI--DQENSEFSSCILDVDNRAYENKFELAELIVRELS
MGRQEEIVAIRGGKRFVRKLERIV-PSKK--QEITIQDNETYVITGGTGHIGGEIARAFFKKAKVNLVLTGREQLPSREN----VIQDLEN----QGAKV
EYFAVDVTNEQKMKEMIQAVKQLYG-SIHGVVHAAGTIHHSKLLSKDLNDIQQVMSSKVQGTIIADMVTRQEPLKFFVTLSSISASIWAANLGDYAAANA
FLNGYSQYRK-NTPGRSLSINYSLWADKGLSEMDLSALAVKAQKLNPLSSEGGTQAFFEVLQYEGKSVHI-LDRQEDNVAE----KVVVLSPSAHPVRYK
--TAKEIKEIVYQVIAAEIN-------------------------------------------------------------CDAESLEVTKNFLELSIDS
LKATKVIAEIGKQLNTELYPTLLFEYQTPEALAEYIEKT-----------
>tr|W4DZ45|W4DZ45_9BACL Linear gramicidin synthetase subunit D OS=Paenibacillus sp. FSL R7-277 GN=C173_11855 PE=4 SV=1
-WIFKKVWKPLSLEEGTVPC-VNILVFEDRHGLAGEFIECMLDETRVISVKQEDCFQVYDRNHYGCDYTRYEGCKELFDYFKQIGWKADHMIYLPTYQIN
--ASGDTDISSSSQLGVFSLIHLLQVLADNDASTSLYVGSSNVFQDAGGLGTRYDNAALIGFMATLDTENTGLRSLLIDLEGRDI---KQDARLLRAEIM
HGETVKEISYRDGRRLTWKLRNVPLRKAE--PKTRIKQGGNYVVTGGLGGIGTKICSQLIENYQANLLILGRSDLGTLEDNDS-RVQ-HYNQLVALGTSI
SYRQADVCDLDSIVQAVEDYEQSKGIQIDGIIHLAGNSSSYLITAIEQQTFAEEFNAKVYGVLNLFELLKSRKEAMLITFSSVTSLLGSATFSAYAAGNS
FLEMFCKYAAGQLGYAVKCISWTMWDKIGMTAGSLINSLSESIGQHVISEQDGLLFFEALLNLGDDMVYVGIDENNVHISHRIDEKVYAKEYLAVYRQ--
-----EDTEALLQLENAKVLDDYGA-----VSTLKMLTVNRDGEV--------IEEEQAEPYVEA-STDAERIISNIWSEVLAAGKIGMNDNFFELGGHS
LKATQVVSRIKKEYGIEFAINDLFYHPTVGALAKLVEE------------
>tr|A0A0M0WWP6|A0A0M0WWP6_9BACI Phosphopantetheine attachment protein OS=Lysinibacillus sp. FJAT-14745 GN=AMS59_10485 PE=4 SV=1
---YGLRWTPQAAEEREFSPEGNILILADRSGFAKELTDRIQTADNLYFVSFGEVYAQLDSTHYTVG-GAEEDYVKLLEDI---GVDFSTVYHLSTLDFN
QSDYTLEQYPETLNQGLYNLAYLTRSFLKINGNVNFVLVTEHAHDVDGEEAIKPANASFLALAKTTQAECPEYEYRSIDIDSR-T----DMNTVLNEVLR
SGEQTFRVAYRNNVRYTEVLTALDVQRD-DIEVVKIKKEGVYLITGGTGGLGLETALNLGGLGPCNICLIGRRQLPAVLKKDKDLIRGIQRL-ESKGCNV
ILRYSDACDVEQMTSITEELKKVYG-HINGVVHCAGVAGDGFLFRKDMDVFNRVINPKIYGTIILDQLTRDQELDFFILFSSMQSLFGGPGQGDYTAANT
FLDSYAPYLW-KKGLAAQTINWSGWSETGMAVDYQVNDS----NFRSLETQVAINALNNVINSNMSNVVPGK-IN-FDVLGQIGADN---------LPFA
------LSA----GLKKNLARQKSKNR---------------DM-GSNEVKQDLVILG-KS---KEYTETEKNVAYLYAIVLDLKEIDIYENFNSVGGDS
IHAMQLLKELGALYPGMVDVSDIFTHPTVEELAEFIDKK-----------
>tr|K4ZHS7|K4ZHS7_PAEAL Polyketide synthase subunit OS=Paenibacillus alvei DSM 29 GN=PAV_8c00060 PE=4 SV=1
---YGMNWMLQSATIQKTQVQGSILVFCDHGEYARALAERIQPQDRLFFVSIGKEFSQIDETHFTVG-EDEEDYDKLLAAI---SVNLCSVYHFSTVDFT
RTDVSAERYGEELHQGLYSVVYLTRALLRIRDSVDFVLLTDYAHEVTGEEAVKPAHAAFLAVTKSTAAEYPNLRYRCIDIDEA-T----DMETVLDEVMT
-DNPTFRVAYRNNQRFTEALTVIEQKQE-SIKRLEIKQTGFYFITGGTGGLGLQMAIDLGNKGAQTICLLARKALPTLLS-DGDLIESILYL-ENLGCTI
LLRYADVSDMVRMESILSELKAAYG-PINGIIHCAGMAGDGFLFNKNMNTFRDVIRPKIDGTVVLDALTKGETLDFFILFSSMTSLLGGPGQSDYTAANA
FLDAYATYLR-KKGIPALTVNWPGWSEVGMAVDYQVADA----VFRSLETEAAIQALNEIIKYDLSNVIPGQ-IN-YDVLQQIGENN---------LPFK
------LSA----WLKKNFDRHISRHN---------------TK-KKQVAKQDVHIIG-KN---DNYTTTENEVAFRYAIVLDLREIDIYESFNSLGGDS
IHAMELLKEINAVYPRTIDITDIFTHSSVEELAGLIDKK-----------
>tr|F5LIX7|F5LIX7_9BACL Phosphopantetheine attachment domain protein OS=Paenibacillus sp. HGF7 GN=HMPREF9413_5750 PE=4 SV=1
---RTTHWIACSDPIDKAVVDDCILVMYRQGQLSS-LMLQM----RQY---FGERIIAVE------L-REACDFDTILSSL---AKEIKYIVHMASLIHE
EMQTGSQTEMELLFKSTF--NLIKALLNQVRHSINLVIYTSNATKVTGEEEIQPLSYGLSGMVNTIGREYANIKTRVIDIDND-T-----SADVLIEDML
SNESLHAVSYRKNVKYMQQLNNVTHGTALNDEQMTLVDNGVYIITGGLGGMGLAISQYLFRLNPIHIVLLNRTY--LL-SEPIDKLEQVQSL-WSQGYSL
DIMQVDIADYIQMDDALQQLRDAHG-AVRGIIHAAGIAGDGFIMNKTWQTYESVLRPKIAGTWVLHELTRNDPLSFFVMCSSYVSIFGAAGQSDYVAANA
FLDSFSYYRR-TLGLPSLTINWTGWRESGMAAVSGIREE----GVRFLNDEEGAAAFWHALKTKLPQVLIGD-ID-YKALEMEHDNL----------IIS
------LFE----NS--------SNHR---------------GN-DQSHWSKDKEIVG-KSM--SDITDIERNVIYAWSQTLGNDEVDIHAKFFESGGNS
LLAAYLQKELDKFYPGIIVITDMFVYSTVVEIAQYIETK-----------
>tr|W4BQD1|W4BQD1_9BACL Beta-ketoacyl synthase family protein,phosphopantetheine-containing protein OS=Paenibacillus sp. FSL R7-269 GN=C162_20681 PE=4 
---YGRVYRPYPLPM---P-SGTVVLAGRISRTER-LLQALK--------ERGHR-------VIEIT-SDSGDWEQPLKLL---SNELSQAIFVWD---T
PGALSSQSWGEVDEAVYQGAAFLKAWSTALKTQAGVIALTHRGWSVGDDETLHPGQAALGGLWRVGALEFETMNLRCIDQDEE-T-----SSDVMLDEFA
DVGRPTFLAYRKGQAYEPVVEDCAVPTQ-AALPVPV-HSGMFVLSGGTGSLGMEVAGLLARRGVKRMALLGYRTIPHLVESSMDRLKQWLEL-ERVLEVL
EVRSVRIEDFEAVAALMSELRSDHG-PIQGVIHLAGRAGSGFLFQKTEETFREVYAPKANGALNLHLVTLEDQPEIFIQFSSISSLLLNPGQSDYTAANM
FMDSLAAYRR-QMGLPALSLQWPAWRETGIAWRMNAVDE----DFTPLNTDEALALFDRIVWRGLPPVIMPG-RT-FKTNGYIQQKP-------------
------------------------------------------KM-LHNTVPQRTQITG---I--TEPDEFDLEVAGIWARTLELDKVEADDEFSSIGGNS
LLTSQMLREYEKIYPGIMEIADLFTYTTIHKQAGYVREQ-----------
>tr|H0BQL8|H0BQL8_9ACTN Putative uncharacterized protein OS=Streptomyces sp. W007 GN=SPW_7556 PE=4 SV=1
---YGYGYRRTGAPPRAGT-GGTVLLCGGFGPLGP-LTGELR--------AAGYD-------HLHVA-DA-DDDRI----G---EGRFAFALL-AA---V
PDDDAAPLTERVIEPVDRTVALLRLLSARPELTGGLLALTRSALAVTDEEAPDPGQAGVLGLTRIAALEYRALGIRCVDVGEG-T-----PPTVLIAEAQ
ATGRPPLVLYRGAQPYEPVVERHPVTLR-EPASGPVPPDGVTLISGGTGGLGQAVARDLLRQGFGPVVLLGSEREGSA-------------P-ADGPAVA
EVVRLDMGDPAAVRRTVLGLRERHG-RIGGVIHLAGRPGIGFLHTKSTDEFMAVYRPKALGAIALHEATQDDDLDFFVMFSSVSGLLLTHGQSDYTAANL
VLDGLAQYRR-AQDLPALSIQWPAWRETGMAARLHAVDE----DFSPVDPAEGTRLLRA-LMTGHPAVLMPG-RR-RAATAVTGAAG-------------
----------------------------------------------RTPDTTERPVVG---L--DGAGAVEQAVAEIWARTLDVTGLDAYDEFDHLGGNS
LLTAQMLRYYDERFPGLMDITDLFRFTTIADQAMCIASR-----------
>tr|J7L0S3|J7L0S3_NOCAA Short chain dehydrogenase family protein OS=Nocardiopsis alba (strain ATCC BAA-2165 / BE74) GN=B005_2046 PE=4 SV=1
---YGHGYRKASPPVEVGT-TGTVLLCGDFGSMDD-LTDELR--------SAGHD-------HLHVA-DTAAVDRI----D---EGRFAFAIL-AG---V
PEDDGTPLAERAVEPVERTVSLLKGLAARPELGAGLLAVTRSALAVTGEE-VDPGQAGVLGLTRIAALEYRALGIRCVDIDEH-T-----PPKALITEAR
ATDRPPLLFYRGERPHEPVVERHAVVPR-DETPGPTPPDGAVIISGGTGGLGAAVARDLAGQGFRNLVLLGSEGRGFG-------------P-QDDPAVA
EVLRLDMGDPEAVERTVREIRERYG-RIGGVIHLAGRPGVGFLHTKTIDEFMAVYRPKALGGIALHEATRDDDPRFFVVFSSVSGLLPIHGQTDYTAANL
VLDSLAQYRG-ARNLPALSVQWPAWREVGMAERLGAVDE----DFPPLDPAEATGLLRE-LMAGRPPVIMPG-RK-RPAANVAEPAR-------------
------------------------------------------R--ADGPGAADRPVSG---L--DHVGEIERAVAEIWARTLDVTELDAYDEFVSLGGNS
LLTSQMLKLYDERFPGLMDITDLFRFLTIADQAACVASR-----------
>tr|H0KBQ2|H0KBQ2_9PSEU Beta-ketoacyl synthase OS=Saccharomonospora azurea SZMC 14600 GN=SZMC14600_22875 PE=4 SV=1
---LRPVWEPAPIEESVPPEGAYLLLARTKDERARLCE-ALRAEAVVVLAEPGAEFARQAEHHFVLNTGHEDDVARLLSELADDGVDVRAVVHALARPD-
-------GTGSEFDDGVGSLLPLCKALLARRGELRMVYLCP---------AGSPAHEAVAGFARSARLENPRLLCHVVSG-ATDAASFRDA----VRELG
VDATRPEQVHRRRVRGYRPMEPESGPL----TTVPLRDGGVYVITGGAGGVGLLLAEHITRQVTSTIVLTGRSEPSDAV---SARMAALE----TRGSTV
RHARVDVTDEDAVRRLVAD-LREEHGGVHGVVHAAGVLRDGFLFRKSRADLAAVLAPKVTGARVLDRATAREDLDFFVLCSSVAAVFGNVGQTDYAYANA
FLDHYASLRQELRSGRTVSIAWPHWQNGGMALSQDAQALRRRTGLTSMSTAECLAAFDDALRSSQSCV-------------VV----------------A
TG----DRDR-----IVEQLAPGGEVRPKAIAV-----------------------APEPMSDTTARRRVLDLLRDTVGEKVGVNDVETTVPLTRYGIDS
VVVTELTNALGDHFPD-LAATAFFEYETLEALADHLADE-----------
>tr|A0A0K0PD94|A0A0K0PD94_9CYAN Malonyl CoA-acyl carrier protein transacylase OS=Scytonema sp. PCC 10023 PE=4 SV=1
---YAPSWRLEDNSPLPNLEESCLLVYPLS--CLPLADAITSSSHKCFRVQLGLASGRLGENLWEVKADDPLAWHCIPALMEKVGSSPLTIYFLSGNQTQ
WGDDNLEVLEESQLQGIVSLFRLFKGIISHNFPLCLKYQ-IKS-----EEAINPLTASLQGFTSSLAREYPQLEVSCLDIDLDDATEEKRQT--WVAPIL
TEPQGEVVALRRGRRTLLPINLP---SV---PKMPFRTKGVYFILGGAGGIGLELCRYLTEAVQAKVILVGRSELDAQK---KETIRTIE----SKGGNI
LYLKADATDLDSMKKAVAE-ARTRYGKIHGVFHSAIILKDKTLENMDESTLRMALDIKVRGSVILHKIFHEESLDFMLFFSSAIAFSGNAGQANYAAGCT
FKDAYAHSLAKKKGFPVKVINWGYWGTVGIVASEDFNKKLAAGGLYSIQPEQGMESITRVLSHPLNQV-------------MPI---------------N
ANEKNAYEEYD----KEQLRTRLSIKIVSATDHYNQCVASNVAAYTKASPVKSRSPVIQKPERARKATDLKTYIEENLVQALDVSDINIKKPLSDYGVDS
ITGVDLINRINKTLKLQLRTTALFDHANIEGFSNAILDE-----------
>tr|A0A0K0PDD5|A0A0K0PDD5_9CYAN Malonyl CoA-acyl carrier protein transacylase OS=Planktothrix paucivesiculata PCC 9631 PE=4 SV=1
---YAPSWTIEENSSRPT-KESILLVYPLP--CLPLADALVFNNHKCLRFQLGLTTRKLGEDLWEIKADDLLAWNSILALREKIGSSSLTIYFLGGVYKN
SENDNLEVLELSQQQGVMSLFRLFKSMISDNFHLRLKYQ-IKL-----GEAIDPYNASLHGFTSSLAREYPQLEVSCIDINLEDVTEEKRQA--YITPIL
TEPQGEAVAIRQGKRKLLPINPP---SV---SKIPFRSKGVYFILGGAGGIGLELCRYLTETVQAKVILVGRSELDTDK---KEIIRSIE----SKGGEI
LYLKADATDLDSMKKAVTQ-AQNRYRKIHGVFHSAIILKDKTLEKMDESSFRMALDIKVLGSVILHKIFQGEALDFMLFFSSAIAFSGNIGQANYAAGCT
FKDAYAHSLAQKQDFPVKVINWGYWGTVGIVASEDFNKKLAAAGLYSIQPEQGMESISRILSHPLNQV-------------MSI---------------N
ANQKNAHEKYD----KQQLRTSLSIQIVSTTDHYNQSVARNVLAYTKADSVKLRSPLIQKPKKERKTTDLKSYIEENLIQALDMSDINMKKPLSEYGVDS
ITGVDLINRINQTLKIQLRTTALFDHANIEEFSTAILNE-----------
>tr|A0A0K0PEK4|A0A0K0PEK4_9DELT Malonyl CoA-acyl carrier protein transacylase OS=Candidatus Entotheonella sp. (ex. Theonella swinhoei) PE=4 SV=1
----------------------------------------LE-GLRCIRVCIGERFRLLEPHYYQLNPRQYDDYASLAQALRQNASWPRRVVHLWQSNEP
DVN-HDQHLSLQLERGFYSLCHFTRALMQHTFACDILAW-QP----------EPACAAVSGFAHTLALEHPGFSCKTIEIPAFLARTIDLL----LSELQ
--ALSDTTVLQRWVQHFCEWQASPIEV----VSKYPRPHGVYLITGASGSLGAQFARHIAAQVKATFVLCARSERTPAC---EQLINTL-R---TMGSEA
VYIRSDLSQRDHVFKLIEE-IQARFKALHGIVHSAGVISDALVFNKTHHQIAQVLAPKVYGTVYLDEATKDIPLDFWVLFSSTTAVTGNVGQSDYACANR
FMDEFAVWREQQRSGKTLAINWPYWRDGGMSMSPGYQGWMERTGLQALPTSEGVAAWDDLLNAPSGHA-------------YVV---------------A
YG----FREL-----LSRMFARPQSAAAQ--PS-----------------------ADEATSSETLYEDTMSWLQHEIASVVKASDIDVDTAFHQFGLDS
VVMRQTNVVLEKKLGA-LPKTLLLEYTTIRDLTDHLSTQ-----------
>tr|S4XKK3|S4XKK3_SORCE Uncharacterized protein OS=Sorangium cellulosum So0157-2 GN=SCE1572_03900 PE=3 SV=1
----------------------------------------GL-ARRILWVRPGARFDISAPDAIAVDPSSPDDYRQLWAHLAGPGSAPAALVLLWPWRLS
ARAADAGDVERALAHGIRAIELLARAMCGAPPETRLVLE-VR-------AGDQPLGEAAAAYGRSLRPLLPQVRFLSLMLPGDLRRLADLL----DRELS
DAPHREVAY-----RGLGP--AEPIPSE---DGAALRERGHYLITGGAGGLGRIFARHLARRCQARLLLLGRSPLDERL---RAELTSLEE----LGAEI
MYHQADVTRARDLEGALAE-AKRRFGPLHGVIHAAGVITGRLLTDKSHAEFEATLRPKIAGTPAIDAVTAGEPLDFFVAFSSASSWLGDMGQGDYAVANR
FMDAYCLHREGLRRGRSVSIAWPLWRDGGMRFADLEQRYLRSSGLTLVEERHGIEAFEAILAGGPVQV-------------MP----------------L
VG----DLSL-----LAPIL---GLSAPRAKPSFNAAAVD---------GVAREAPAGGGGAAGPAREQIEADLRKSIAAHFKVNELELDDHLGALGFDS
LMLTELADRMSRRYGVEVLPTVFFSHNTVRSLAAHLVEA-----------
>tr|A0A060DS91|A0A060DS91_AZOBR Uncharacterized protein OS=Azospirillum brasilense GN=ABAZ39_27230 PE=4 SV=1
----------------------------------------LA-LGPALLVTPGTALRHG-GGRAEIDPADAAHYRSLIQDAVSRGAGPAAIVVAWAGRLP
TD--PAV-------QGIHAVRHILRAVIDAGHLVRLLED-SAD-----AAAAAAVFDAVAAYAPSVKPLLPNLGVTCLRVDPSIAALAARL----CGELA
--PEPEVAYVVRRVRVLGPVSTALAPSG---DGVAIRAGGVYLITGGAGALGRIMARHLAARGAGQVVLVGRSAPEA---------VSLEE---LAGPVF
SYRQADVTDAASLGAAVAE-VLERFGALHGVIHAAGAFTGRPLTAKTPEEFAATLAPKLDGTVALDRATADLPLDFFAVFSSVSAELGDFGQCDYAVANR
FQSAWGLWREGRRQGRTLSIGWPLWRDGGMHTEAAEELYLRTAGLAALESAEGAELFDRILRSGRSNV-------------LL----------------L
KG----EPER-----AARLFATRGIAGPRRAAAASLVA--------------SALPPTAAADGAPIADRLRRDILHGIAQSASVPTVERAGHLGDLGLDS
LMLSDLADRLNAGLGIALSPTTFFSHGDLDSLTSHILAE-----------
>tr|T1SF57|T1SF57_MYXFU Polyketide synthase OS=Myxococcus fulvus GN=mxnK PE=4 SV=1
---KVPSWKESPASMASAQDVRAVVVDSRGEHAGSFIERARR---VQVVSAGGGDFTAVFETLYVLDALGADELD-------------------------
-----------EAERALQSLFLLVKAHLRLASEFRVLFVATDS-----DYGEGFAAAALLGLAKTAMLESPRLQVSLVDVDALDAVGMEAL----LREGM
VEGRAEDLVGRRLVRELRALQAGQ-SS----TASLFTGGKNYLLVGGGGGLGRALIDHLAARVSCRIFVMGRSARSSPE---ST-----E----GRQCEV
HSLRCDVTDRRQVEQAIQQ-LTADFGPLHGVLHLGGVLSDKLLLTKSWEEFQRVLAPKLAGTLFLHRATQDQPLDFFIGFSSIVSLLGNVGQADYAAGNS
FLDAFMAFRAR-APGRSLVVNWPLWEGVGMASRTADRSVEVR-HLRPIRVEAGMRAFEAVLAQGDSVQ-------------VL----------------V
QG----G------------------ARPDAKKP-----------------------LPAV---VAQVRNVEGYLRELVAKRLGLPGFDETESFFTMGLDS
LILQELMAELDREFSG-LPPTLVFEHPNLKKLVAYFEKQ-----------
>tr|D8P4C8|D8P4C8_RALSL Polyketide synthase, rhizoxin biosynthesis OS=Ralstonia solanacearum CFBP2957 GN=rhiB PE=4 SV=1
---LVEKWRRSSFQDLTPPDGRLLLIGNDPEGHRQLTTRYPQ--------------------AVALLLDGSESVEQLIEQLRGAGPA---EHLVWLAPAA
PVRADVGGMVRAQQGGVLACFRLIKALLALAFRPLAWAQAVFGDAGAMAEPVSPAHAGVHGLIGAMAKEYRHWRVRLVDLPAGDLNLLSLP---------
--PHGDALACRNDVWYLAPCLPPPGPGA---ADSLYRDRGVYLVIGGAGGIGRLWSEHLIRTRRAQVIWLGRREQNSQI---DAAIAELA----RLGPAP
RYIRADAGNHAALSEAVAQ-VCAEYGTIHGVVHAAIQLQDQSLARMDQQRFAAGLAAKVDVCVRLAEVFEHQPLDFMLFFSSLQCFTKSAGQSNYAAGCT
FKNAFAHYLAQQRAYPVKVINWGYWGHVGSVASEDYRRRMGEAGLGSIEGEPAMAALETLLGGPLAQL-------------TFL---------------R
ASRRGREREV-----IAEMKQRSGLARPVAYDFFNDVMLDAMVEFVKVAPKAPAVPASREVTRAVLKDQAVRYLKEVVGGLFKIRQIDAREPLETYGIDS
ILVVQLTNLLRDKLSG-ISSTLFFEYQTIDALADHLVAS-----------
>tr|I7J4E8|I7J4E8_9BURK Polyketide synthase domain protein RhiB OS=Burkholderia endofungorum GN=rhiB PE=4 SV=1
---LVEKWQR--FQDLIPPNGRLLLVGNDPQGHKQLTTRYPQ--------------------AVSWLLDGSESIEQLTERLREAGPI---EHLIWLAPTT
LAQENLDGMIRAQQRGVLGCFRLIKALLALALQSLTWVLTLFDEADAVTGPVAPAHASVHGLIGVMAKEYSHWRVRLVDLPAGDVDPLSLP---------
--PRGDALACRNDVWYLAPYLPLSELGE---VDSLYRDGGVYLVIGGAGGIGRLWSEYLIRTRRAQIIWLGRREQNNDI---DQAIAELA----KLGPAP
RYISADASNHAALRQAVAQ-ICTEYGRIHGVVHAAIQLQDQSLARMDEQRFTTGLAAKVDVCVRLAEMFAHQPLDFMLFFSSLQSFTKSAGQSNYAAGCT
FKNAFGHYLAQQCSYPVKVINWGYWGHVGSVASEDYRRRMADVGLGSIEGEQAMAALDILLAGPFSQL-------------TFL---------------R
TSQRSGEREI-----IEQMKQRSGLHCPAAYDFFNEVMLNAMVEFASKGLTVRAAPASREVTSQALKDQTVHYLKQVIGGLFKIRQIDAGEPLQTYGIDS
ILVVQLTNLLRDKLSG-ISSTLFFEYQTIDALADHFVAS-----------
>tr|K9EIF2|K9EIF2_9CYAN KR domain-containig protein OS=Leptolyngbya sp. PCC 7375 GN=Lepto7375DRAFT_0419 PE=4 SV=1
-------------------NAAIAIIGGTPEQLRAIHKNYPA----------------------PLQL---PNTADLKQWSAVLDRLPELDHILWIAPET
EPLLVDDRVIEAQDIGVIQVFRLVKALLSLGYKTLGWAQAVLQ-----TEPIHPIHAGIHGFVGSMAKEFPQWQVRLLDLDAQPALWTIP----------
--PQGEALAYRGNQWALIPVQDL---AV---NPEPFRTQGTYIIIGGAGGLGEVLSRHLIQHWQAQVIWVGRRPLNLDI---QTKIDALA----ALGAAP
WYLSADAANVSDLERVRNA-VQQKCGSIHGVVHSALGSYDQSLTAMDEAQFRSVLSAKVDITVRVAQVFAEEPLDFILFFSSLASFGKVRGMSSYVAGCV
FQDAFALRLSQICSIPVKVINWGFWSIGGGARITLRRHLQETEGVQPINADVGMGVLAQCISSNISPL-------------AFI---------------K
SDASNGVIEN-----SATLRQRTGVTITVEDHFFNTALAEVAAAWIASPGVERGQPPES---HTVPTVDKSAYVQQCLSRTLRLDRFELDVSFSDYGVDS
ILGAQFITLVSAALDIDLNTTIIFNYPTVERLSAHVVEA-----------
>tr|A0A0G8DEH0|A0A0G8DEH0_BACCE Beta-ketoacyl synthase OS=Bacillus cereus GN=TU66_14315 PE=4 SV=1
-WFYTPQWKSSTLIESNHDVNETWIVFVDQEGLGNEVRDLLNKGQRVVTVEPGFGFNKENNDRFIINPEERTDYVKLLDEVQEICGLPTRIVHMWGITDE
ERQASIEYVNCKQNLGFYSMFYLTQALGDKSDSISIQIITNGVQQVIGDEELIPEKSTVLGTSLVVPQEYSYLSCSSIDVVLPVNKELKRLINQLVEECL
SNTNDKMIAYRGNKRFVQTYEPLQLEQPAKEKLPL-RKNGVYLITGGLGGIGTILAKHLAQTVQANLVLLTRTGLPNYSE----RIRKVLE-IEETGSKV
YVLAADVTDQSQLYEAIHKAEQKFGK-INGVIHGAGILGGNLIQELEKEDCEEQFSAKIYGLLNLEECLRNKDLDFCVLMSSISAVLGGLGYVSYAASNI
YMDVFAQYINRYSNLPWISVNWSDWKEKDMQIGA----SVHE---LSMTPEEGVQAFNIALS-------------WKQGEVLIHSPGELQADQWVLNSFN
DE----KEEEL--------DSTLYHSRP--------------------------QLL---TEYVAPRNEVEEKLSKIWRNIFKVSEVGVHDDLLELGGDS
LKAITIVSKIHKEFNVEVPIKELFTLSNIEKLANYISRADK---------
>tr|L7UIH3|L7UIH3_MYXSD Non-ribosomal peptide synthetase OS=Myxococcus stipitatus (strain DSM 14675 / JCM 12634 / Mx s8) GN=MYSTI_04971 PE=4 SV=1
DWTYEVSWEPRPLAPAGTARPETWLVFTDEGGVGVSLASLEAGGARCVWVRPGAAYSSQGGSAFTVDPARADDFARLFREVAGPGPACRGAVFLWGLDAR
AE-----------VPACQGALLLAQELARAVVSPRLWMVTRGVQCTGHESVPAVLNAELWGLGRAMALEHPDSWGGLIDLDAVADA---REPELLMAELR
QSPEGEQVAYREGQRWVARLTRCPVSNPARPPGARVHPEASYLITGGLGALGLHVARWLVDQGARHLVLMGRSAVGEAAR---DEVRSL----AQAGASV
DCVQGDVSHPEDVSRIL-GAIAASGYPLRGVVHAAGVVEDATLLSLDWKRFERVLAPKQQGSWNLHQQTKSLPLDFFVLFSSSSAVLGAAGQSNYAAANA
FMDALAHHRQ-ALGLPAVSINWGPWSGAGMAASLE--VPEQRRWFDWIDPAQGLELLGQVLDSGRTQVAVPVDWSRYARR------------------Q-
------------------------SESGAVGLLRNVLDDARVSLPRVVPMWERLKGQ--------QRNRQETLFDHIHQQVAQVLQMSGGLGLFDAGLDS
LLAIELRNRLQTSLGRPLAATLVFEHPSIDSLTEHLATE-----------
>tr|Q70P96|Q70P96_9DELT MelD protein OS=Melittangium lichenicola GN=melD PE=4 SV=1
QWTHEVRWEAQPHDAGEAVLEGTWLVLADATGTGDALVSLRGRGVRCVVARPGAAYAAHDGQTFTLDPSRMEDFSRLLRDASAPGPPCRGIVHLWGLEPD
APVT-LASLREAQRLGCESVLHLTQALVRFPVRPRMFLVTRGTQRTGQETPPALAQSALWGLGRTLALEHPEFSPALVDLDSRAPS---TEDASLIAELL
HVPRGEQVAYRQGQRYVARLARYAGSD-ARSAASRLRPDGAYLITGGLGGLGLQVARWMVERGARHLVLMGRKEPGEAAK---ESLRAL----RQAGAEV
TLASGDVSQPGDVARVL-ASLAQTKTALRGVMHLAGVVDDGTLLHQNASRFERVLAPKQAGGWNLHEQTRGMDLDLFVLFSSSASLLGAAGQGNYAAANA
FLDALAHHRR-ALGLKAVSINWGAWSGHGMAAAFA--SPEQQRGSEWIDPERGLEALGQAMEEGPAAVAVPVDWNQYVQR------------------F-
------------------------AS--SANFLRKLIEPGRVGTPGEATLVDRLKGL--------PRGRQEVLLDHVHQQVHQVLALAGNDRLFDAGMDS
LMAIELRGRFQSSLGRTLAATLVFDHPTIDALTHHLATE-----------
>tr|Q5MD34|Q5MD34_9DELT CtaD OS=Cystobacter fuscus GN=ctaD PE=4 SV=1
QWTHEVRWESQPREAGETVLEGTWLVLADSTGTGDALVSLRAKGARCVVARPGPTYVAQDEQTFTLNPERVEDFTRLLQDASAPHPPCRGIVHLWGLEKD
APVS-LASMREAQRLGCESVLHLTQALVKLTVFPRLWLVTRGTQRTGQETPPSLAQATLWGLGRTLALEHPEFSPTLVDLDPSEPS---TEDASLLAELH
QAPRGEQLAYRQGQRHVARLARYEGAD-TRSTAPRFHPEGAYLLTGGLGGLGLQVARWMVERGARHLVLMGRKEPNEAAR---ESLRAL----RQAGAEV
TLASGDVSQPGDVARML-ASLAQTKTALRGVMHLAGVVEDGTLLNQEASRFERVLAPKQAGGWNLHEQTRDMDLDFFVLFSSSASLLGAMGQGNYAAANA
FLDTLAQHRR-ALGLKAVSINWGAWSGHGMAAALY--SPEQQRGAEWIDLERGLEALGQALEQGPATVAVPVDWNRYVQR------------------F-
------------------------AS--AASFLRKLIDPARTGAPGETPLAERIKGL--------PRGKQEALLELVHQQVHQVLALAGSDRLFDAGMDS
LMAVELRSRFQSNLGRPISSTLVFDHPTIDSLTQYLATE-----------
>tr|Q9RFK8|Q9RFK8_STIAU MtaD OS=Stigmatella aurantiaca GN=mtaD PE=4 SV=1
EWTYDVSWEQRPRSGIDAVLEGTWWVLADSAGVGTRLVALQSHGARCVVVRPGPAYEARADRTFVLNPARVEDFERLLVDSQGPALPCRGILHLWGLDEA
P------SLEAAQELGCRSVLNLAQALGKLEVSPRLWIATRGTQRTGHEQPPSLTHAALWGLGRTLAVEHPELSVALLDLDERAHA---SEDSLLIEEFL
LDPDGEQVAFRNGRRYVSRLARCAVPN-TQPSATRLREDVSYLLTGGLGAIGLHVARWMVERGARHLVMMGRTEAGSAAQ---EALQSL----REAGARI
RLEQGDVSQPGDVARVL-ASLAQSGPPLRGVMHLAGVVEDSMLQQQDWPRFKRVLAPKLQGSWNLHHQTKEMDLDFFVLFSSSSALLGAAGQGNYAAANA
FLDSLAHHRR-ALGLKAVSINWGPWSGGGMAASFA--GSEQRRWVDWIEPAQGLELLGWALDAAQAQVAVPVDWAKYFQR------------------F-
------------------------GDTGATKFLSRLLEETRSGTAKQPKLLERLKGL--------TRNRQDVLLEYVYSQVTQVLPLAGNQRLFEIGMDS
LLAVELRNRFQSTLGRPLSSTLVFDHPTVEALTGYLAAE-----------
>tr|G4RJD0|G4RJD0_CHOCO Non-ribosomal peptide synthetase/polyketide synthase OS=Chondromyces crocatus GN=croI PE=4 SV=1
TPLHRIAWEPAPAVAPGMVSSGPCWIFADEGNAGSSLRHLERTGVHCHLIRRGERLDTPGPGIHTLDPDQPEQLDQLLDTL--AQGKPRGIVILWPLDES
PGDPGMGGALAATQRLCSRALTLVQKLAPSAGDGRLWLVTRGAQTVGTNAPVSPTQAALWGFGRVLASEHPEFQSGLIDLDPESSA---DEASHLAAALL
ASTDEDQIALRGGRAHHA--RPQPDT-LPVSGRRPVLGGGVHLITGGLGGLGLLLGRWLAHAGAETIVLMSRSTPGPEAI---RALDEL----KTGPARV
RVMQVDVSRADALSAAL-DTLRREEGPLRGIFHLAGSLSDAVLLRQDPERLHAVLAPKVAGASLLHALTLHDPLEHFVLFSSIAAVLGTPGQANYAAANA
FLDGLAQHRR-ALGRPALSIQWGPWAGAGMAAEQG----AADRGFESMPPEQALALLERLLGGAAGDIGVRVDWRLLLAR------------------L-
------------------------PTVP--PLLVEQLPAEARTARAAAGPPAWIRSL--------EPEDEGLLRARLLDLVRQSLPIDPRMPLHELGLDS
LMAVDLREAIGKSVGLRFPATLLFNHPSIEALVAFLRRE-----------
>tr|C5ANC8|C5ANC8_BURGB Short-chain dehydrogenase/reductase SDR OS=Burkholderia glumae (strain BGR1) GN=bglu_2p0590 PE=4 SV=1
DRLFAPRWQRLDDLVI-PLPADDCLIAGDGAGAGAALARLRGVGVRCLRIDAASHTSDELT-VALADPASEAAWRDTLRAAAARAQGTLQVVDLRALDLG
VGAEVPADALAVQAQLCGGALALVGALTQVDRPVRVNFITRGAQEPGGTNVERAAQATLIGLARVVAAEHPEWGCRTIDLDPATAD---P-AAALAPLLH
AAPDELQLAIRDGAVHAARLKPARRD------APSLESNGSYLITGGLGGLGLRLAQQLAKAGVKRLVLMSRGAPDAAAT---TAIDAL----RQLGCTV
DLARCDVADPAAMRLAWHETVLSGPFPLKGIFHAAGALRDGVLGGQSWAEFAVPLHAKVAGALNLHALSLDAPLDCFVCFSSISALFGTAGQANYAAANA
YLDALVGARR-TLGLPATSIQWGPFAEVGMAASLD--RAHRDKGLQLLAPDELLKHIEAARRADVATVVINDDWQRYAQT------------------E-
------------------------PSEGVRKLLADWLPTEAADTAR-HDERDRFDAL---------PALRDALAIYLQAQIAVMLEVAPTRGFLELGLDS
LAAVEFRSKVQRDLRLSLPATFAFDYGNVELGADFLFER-----------
>tr|F4Y2Q3|F4Y2Q3_9CYAN Polyketide synthase module OS=Moorea producens 3L GN=LYNGBM3L_69620 PE=4 SV=1
DWFYIPSWKRSIPPAYEKLLESDTLVFIDECGLGEKLAKLAIQGSDVVRVSRGSEFAKQSDRVYTINPTQADDYHTLLQELKQ-LKNPSSIIHLWSVTPN
NHTEGIESFEASQDLGLYSLIFLAQALDKLIDPLQLTVVSNNLQEVSGEEVLSPEKATLLGACKVIGQEYPNINCRSIDIVLPPSQ---KQLTQLLAEIT
AQSEDLTIAYRGKHRWVQKFEPMGLE-TPGAETLPLTEEGVYLIIGGLGAIGLSLGLHLAKTVRAKLILIGRSQFPSRKI---QKLQAM----EAMGAEV
MVLSADVADGQQMEAVV-AQAEARFGNINGVIHSVMFTGDKATKTDIWQHF----QGKVQGTIVLSKVLHNKNLDFCILMSSIASVLGGLGDVAYSAANL
FMDVFVHQNR-SNSVPWLSVNWETWEFEKQDQNY-------EIAEFAITPEEGIQAFERVLSTQELNIGDQARIDRWVK---------------------
--------------------------------LKSVKQQNNSHNQVPVTFRKQLETV--------PVGEQGLLLTHVRAQVAKVLRITLEQKLIDLGLDS
LMSIELRNALQLSLGFSVPSTLLFDYPTPEALTSYLAQE-----------
>tr|A0A0K1SB62|A0A0K1SB62_9CYAN Uncharacterized protein OS=Moorea producens JHB PE=4 SV=1
NCLYQVEWRIKERQSS---KPKNWLIFTDAQGVGQQLVLLQSQDQGCTVVFPGKEYEQIAEHKFRIDPANPQHYQQLWEKI----SNIDGVVHLWSLDSS
-L-----DLELASRISCGSTLYLIQTLLKGKPP-RLWFATRGAQAVGANAVPGVAQSPLWGMGKVIGLEYPEFNSVLVDLDPNPAV---DEIQTLWAEIQ
SEDKEDQVAFRNQARYVARLVSRSPV-VETNKPLVFDNDRSYLITGGLGDLGLLVAQWMVEQGAKNLVLVGRSSPKPAIE---HKLRKL----ENLGARV
VVAQADVSNAGQVTELL-TQIEQSSLPLGGIVHCAGVVEFSGLSQQDWQRFAQVLVAKVQGTWNLHALTQNQPLDFFVCFSSIASLLGSHGLGSYGAANA
FLDSIAAHRQ-ALGLPALTVNWGPWGELGMGAKLS--TDHQGRGLANVAPKQGLFALEQLLQQDLAQVGVSVDWQKWLRQ------------------F-
------------------------HSLP--PFYEDVAPNTTVNTTVNLDFKTELEAV--------PANQRDLLVERVRTQIAKTLQIELGQRLIDLGLDS
LMAVELRNHLQSSVGCSLRSTLVFDYPTIEAMVDYLSQE-----------
>tr|B1GYG6|B1GYG6_CHOCO Hybrid polyketide synthase/nonribosomal polypetide synthetase OS=Chondromyces crocatus GN=ajuL PE=4 SV=1
---HETVWREHHPSADSIRAPARWLLLADEGGVGEALARLRARGSHVVIARRGAQCSEESPGLWTVAPDRPEDLVELLTRAFPAGGGPGAVVYLWTLDAP
ALSGDAT-PEAAEPLTCGSLLLLTQTLARHDLGPRLWLVTRGAQPVEAGAPVAAQQAPALGIGWTLALEHRTLWGGAIDLDPRAPD---GEIEALCDALC
APGGEDRIALRSTPDRGLRRVPR--A-FDSVPAWRPQRGSTYLVTGGLGGLGLRLARWLVERGARSLVLMGRSAPSPAAS---EILSTL----RERGAHV
EIAQGDVARAEDVTCTL-SIIAHHASPLGGVFHAAGVLDDGMLVGQDPARFHRVLAPKVQGAWNLHVATRDLPLDSFVLFSSGASLLGSAGQSSYAAANA
FLDALAHQRR-AEDLPALSVHWGPWAEAGMAASLT--QQDLERGVGLIPPAEGLALLGELLGGAPPEVAVPMDWNKASET------------------F-
------------------------GRTG--RLLSELTRA-------PVKMRSWLDPL--------P--EHDALLTHLQRRIADLLLPEANQGLFGMGLDS
MMTLELRSRLELEASQPMPATLLFTYPTIDALTRYLLGE-----------
>tr|L8LXN2|L8LXN2_9CYAN Amino acid adenylation enzyme/thioester reductase family protein OS=Xenococcus sp. PCC 7305 GN=Xen7305DRAFT_00005970 PE=4 SV=1
NALYQIEWQPKKLDSTANTNTQNWLILADTQGIGEKLAKLQAQNQSCTLVFPAQEYQQVEANEFHIDPYNPQHFQQLVTDL----PAPNRIIHLWSIDIA
KPEL-TEDISQSSQLGCGSTLHLVQALLGNDPP-SLWLVTQGTQAVAKY-VTGIAQSPLWGLGKAIAAEHPELNCVRLDLDPQEKE---DAVKILWSEIQ
AQDIEDQIAWRNNIRYVSRLKRHSKS-ATNGESLTIKQDSTYLIAGGLGDIGLKVANWLVDKGATHLVLLGRSHPKSTAI---TQLDKL----QQLGVKV
IVTQADIANHEQVDSVF-KQIKKTLPPLKGIIQAAGTTDDGIVRNLTWDKFAKVLAPKVQGSWNLHTCSAACDLDFFVVFSSIASLLGSAGHSNYVAANS
FLDSFAAYRR-SQGLSALAINWAVWANIGLASRNL---QVLDRGIGSITAKQGLQILDRLLQEQPTQVGFPIDWSLFSEE------------------S-
------------------------WSDA--NFFKDLKQES-ARSLISLTFRQQLAKT--------TVENQKLLSNHVCTLIAKTLKLDISARLIDWGLDS
LMSIELRNHLQSSLSCSLRSTLFFDYPTTETLLEYLASQ-----------
>tr|Q9RFL0|Q9RFL0_STIAU MtaB OS=Stigmatella aurantiaca GN=mtaB PE=4 SV=1
-KLFQVRWQSMPLAPAVPE-RGPWLLVADRGPAGEELAALKREGQVCHVLAAPESAVTGEA------------LLQRVEEALA-LEAYRGVVYLSALEAE
QE--SPQGKSQAALEGVSGAVQVLQAIAKLERGPRLWLVTRGAQALESPRPLALAQAPLWGLGLAVRDEHPELRCTLIDLDPDPAADG---VGCLFQELL
TPDREDRIAWRGGARFAQRLSFLEAVPEP--GTAPISPDGTYLITGGLGGIGLRCARWLVDAGARHLALLGRSGPSE---AARSVLGALE----AEGVTV
RVLQADVAVREDVSKVLSALRV-DMPPLRGVLHAAGLLDDALLVRQDRDRIQRVLQPKVAGALNLDLETRGDPLDFFVLFSSIAAMLGGEGQGNYSAANA
FLDALAFARR-AQGLPAHSLAWGPWAEVGMVAARSESAHLAALGIESIPPDEGVAILGRLLRAASAHVGIFIDWTRW------------------QQRHA
-EGHAPLLAGILKQQAAA----P--------SQ------DS-SEE-APDI-QELIRA----TPEERQKRAEAFLRREVTRILDLPLADGRLPLVRFGFDS
LMSLKLKARLESTLGLSISAAKLLSGLSLDKLVALVLER-----------
>tr|A0A059KPH2|A0A059KPH2_9BURK Uncharacterized protein OS=Sphaerotilus natans subsp. natans DSM 6575 GN=X805_09770 PE=4 SV=1
-WLHRVDWSRDAFGTALPAPASDWAAQ--GGGAYETCVALETLAGQVLAAWRQAGVAFEPGARWTVAVPAHRRLTGRLLEILGELGWDEGTGTDWTVRAV
PA--EP-------LRRCGDLLDVLQGRVEGDTRHRLYAESPIHRLMEGLRLLEVGG-GTGGTTVGVLPRLPAQRCDTLDIERSPLEQGF--ARGQADV--
--------VLAANVLHATRDL----SVGT--EALRCEAQATYLITGGLGGLGLATADRLVARGARHLLLLGRRAPDA---AAQARLAALA----AQGVEV
RVAAGDVADGAALAALLASIDP-RW-PLRGVVHAVGVLDDRPVLHQDGASLDRVLGPKVRGAWNLHRLTQGMRLDFFVMYAAAAGLLGNRGQANHAAANT
ALDALAAHRR-ALGLPALAIDWGAWADIGAAAQLMRGAELVSRGLTAMAPEQALAALEALMATGARAPAHLIDWATY------------------LRSSG
EVGRLPYFAALAALQPPG----T--------PAGSSPGAGATTTAAPVPLRQQLAEV----RGAERAEILTGWLQQAVADTLRLTLPDSHTGFSDLGMDS
LMTIELRRHLSRALELPLPSTIAFEYPSVAQLRDHLLAE-----------
>tr|Q3LRL4|Q3LRL4_9DELT MmxC (Fragment) OS=Cystobacter fuscus GN=mmxC PE=4 SV=1
-ALYEIGWKR-QPLGGVPA-SGRWLVFTDGSGTAEALAELRWSGCRPVLVHPGEAFVRHDGEHFTLDAQRAEDYARLLAEAVPPGESLGGVVHLWAMRG-
------ESLHAAHLLGCASALHLAKAL--VGAAARLWLVTRGARTLSGSAPLALEQVPLWGLGAVFSQEHPDQCGALIDLEPTASEQD---ALAIWRELG
ATDGERQVMIREG------------EPRD--AMPRLRPDASYLLTGGLGGLGLSLARWMVEQGARNLVLIGRGGPRP---EAQEALRALE----TAGARI
LVLQADVSKREEVRRVLEE-AG-RLAPVRGVVHAAGVLDDGVLLQQDWERFARVLAPKVDGAWHLHELTRERELDFFVLFSSAATLLGAPGQGSYAAANA
FLDALAHHRR-ALGLPALSINWGPWAEVGMAARL--ASHFQAQGIEAFSPDVGLRMFGRALAHGQPQLTLLVQWSRY------------------LAQYP
RGAAPTLLAELSGRAVAE----P--------EA------SE---QPSAEFRRRIESAE----PRQRLSLLMEHVRGEAARVLGLDPLESRQRLFEVGMDS
LMALDLRKRLQNSVGAALPSTLVFDYPTTEALASYLHDE-----------
>tr|A4D934|A4D934_9NOSO CrpB OS=Nostoc sp. ATCC 53789 GN=crpB PE=4 SV=1
-WLYQIHWQTQSISIDLTK-SGSWLLFSPPTGIGKHLVELEQQGWHCILVTPGENYQQLESQHYQINPNHPEEFLHLLQSSLEQQPPLRGIIHLWSLDST
IA--L-QELQKSQELGCGSVLHLVQALVKNQDMAPLWLVTQGSQSVGESLPIQFQQTPLWGLGRVIAQEHRELQCRCLDLDPTMEDSQT--VAALLEELL
SPGDENQIAYCQGVRHVARLERQQKEYKS--LDNLIQAEASYLITGGLGALGLKTAEWMVQQGVKYLVLTGRRQPSA---KAQQTIEQLQ----KAGAQV
LVLCGDISQQENVARIIESIKV-SLPALRGIIHAAGILDDGLLLNMNWEKFTQVMAPKVQGAWHLHNLTQNLPLDFFVCFSSMASILGSPGQGNYAAANA
FMDGLAHHRR-GMGLPGLSINWGPWAQEGMAANLDSQDRMVSKGMTFLSSEQGLQVLGQLLEQSIPQVGVLIQWSVF------------------QEQFS
FGNQIPLLSQLVKESKSQ----Q--------KA------LK-TKTKHNEFLEQLKAA----LPREREKLLIIYIKDEISQVLSLSQIDMQQPLNTMGLDS
LMAVELHNRLQTDLLVDISIVKFIEDISIVDLATEVNEQ-----------
>tr|A0A0B5ET01|A0A0B5ET01_9ACTN Modular polyketide synthase OS=Streptomyces albus GN=SLNWT_0891 PE=4 SV=1
-TLNRTVWAQAGLFLFRLVEVEVAAVNGPRASVLSGDADAEAVGHRIKRLAVSHAFDLCSPAYWVRHQDCLPTDTGAEP-HGSAAPPQDRFVLL------
------RALTEAVAGGPVAVLACPASATLDEVGGRLWCLTRGAVSVSSGEVPDPVLAQVWGFGRVVALERPQTWGGLVDLPRDGKGG-------------
--------------------------------ADWRMPSGPVLVTGGTGALGAGVARWLAGRGAEHLVLAGRRGASAP--GAEELVRELE----ALGVRV
DVVACDVSDRGSVAALLA------EFVFSAVFHVAGVVDDGVVGSLSAERFAGVWGPKAGGAELLDELTRGMDLSAFVVFSSFAGAVGGAGQGNYAAANA
QVDALVERRR-AEGLPALSLAWGPWADGGMAVDE--VERMRLAGMTPLRQDTAFGVLDRALAADLTTATVVIDWERF------------------APGFT
SARPSPL---------------L--------AALPEVAAGQRGGPEAEPLTARLAGL----SPAERHEALLDLVGTHAAAVLGHGGIDAEGAFKDLGFDS
LTAVELRNRLGAATGLALSATLVFDHPTPNALAAHLLGK-----------
>tr|S4XS92|S4XS92_SORCE Uncharacterized protein OS=Sorangium cellulosum So0157-2 GN=SCE1572_16945 PE=4 SV=1
-LLYRLEWRRKDLEGGGKP-RGAWLVLSDRGGTGAALSALERRGESAVRVLAAERYERVEPRRYRLDPSDASGYAALLADAFSEEQPCRGVVHLFGLDAT
AP--E-ETLLEDQRLGSLSALLLSKALVGRGFRPRLYLVTRGAQSAGEAQSVRVSQAPLWGAGRAVGAEHPELGCTRVDLEEGAPEHG---VEALVDELV
AREREPEVALRGSGRYVARLVRGPAGVEG--SGVRLRPDGSYLITGGLGGLGLSVGRWMVERGARHVVLVGCSGPTE---QARAAMREME----SAGAQV
LAVQADVSQRASVARLLSELGQ-RLPALRGVVHAAGVAVDSTVEEETEERLLRALAPKVQGAWNLHSLLSSPPLDFFVLYSSTMSVLGPPGSVNYAAADA
FLDALAHHRR-AQGLAATSIGWGLFSDVGAAARAGVAERLASRGMPGLTEAQGAEVLARMLAGGEAHALAMRHWIEF------------------YPSAA
---TSPLWEELRNERVEA----A---------P------GA---GRAAELRKALEAM----RPEDRPAALQQLVREQAALVLRLDRIERDTPFMSLGFDS
LMGLELRNRLEAGLSVALPATLVWTYPHIAALSTYLLGK-----------
>tr|D9W5P0|D9W5P0_9ACTN Modular polyketide synthase OS=Streptomyces sp. C GN=SSNG_07470 PE=4 SV=1
-GLFRLDWTELPAG-----AAGNWAVLGSDPAGIAAAL-----------------------EGAGAAVDRYEDLAA--L-AAADGTA--QTVVL------
---------------------------------SRLVVLTHGAVATRGEDATGLAHSPAWGLIRSAQAENPGRLL-IADLDTTAESAAA--LRGAVA--A
LVHDEPQTALRAGTALAPRLVRAGS-------PQGWDPDGTVLITGGTGTLGALLAKHLVHHGVRHLLLAGRRGPDAP--GAAELVAQIA----DLGGTA
EVVACDAADRDALAALLAAIP--ADRPLTGVVHAAGVVDDGVFASLTPARMERAMRPKTDAAWNLHELTRDLDLSRFVLYSSAAGVTGNSGQANYAAANT
YLDALAHHRR-AQGLPATSLAWGMWHQTSELTAGDDLARFSRGGVTPLTAEQGLALFDAAVDQDEALSVPVLDPAAL------------------RDSAG
GAGLPALYRSLVRTPVRR----A--------AGA----AAAAEPDG-SALLRKLAGL----SAERRRGVLLDLVRTNVAAVLGHSSVEADRAFKELGFDS
LTAVELRNRLGAATGLRLPATIVFDHPTPVELADHLRDE-----------
>tr|D0LQW0|D0LQW0_HALO1 Acyl transferase OS=Haliangium ochraceum (strain DSM 14365 / JCM 11303 / SMP-2) GN=Hoch_2954 PE=4 SV=1
-GLLRVDWSDPRAF-----AAQEWALVGPEDASLISHAN----------------------SLTH-----HQDLNALLE-SIERGGA--EVVVVPSYDVA
---------------------------------ARLIVVTRGAIATRDEDVLGLAQASLWGLVRVAQSEHPDASLTLVDVDNREDSLHA--LFGLFGAPN
ALAAEPQLAVRAGNVSVPR-------------ARPFDPAGTLLITGGTGTLGRLLARHVVKHGARHLLLASRQGLAAP--GASELVSDLA----EAGAEA
TVVACDVSDRSALQRLVAAVP--ANHPLTGVLHLAGVLDDAVIESLTPKHFDTVLRVKLDAAYHLHELTLEHDLAAFVMFSSLSGVLGSAGQANYAAANT
FLDALAHHRK-AQGRHGLAIDWGYWEDRSALTAHTALQRFARSGLRPLSAQEGLALFDAALTRPDAVLVAVLDAMAL------------------AKH--
ANALPPLLSGLVPAKVAR----P--------MAST--GT------SVASLQQRLASL----VVEERAPALLEIVCSEVATVLGLAALDPERPLQELGLDS
LMALEIRNRLSAATGLRLRATLLFDHPTAAALTQALLGW-----------
>tr|A0ZEC2|A0ZEC2_NODSP Malonyl CoA-acyl carrier protein transacylase OS=Nodularia spumigena CCY9414 GN=NSP_42160 PE=4 SV=1
-CFYQSQWKQLNSIITVKS-EKSWLVFVHPGAGLHQVINLQQAGERVITVELGDGYKCRSQDDFVINFEQKSDFHRLYQEAYPAGEFPTGVIFT------
------TEYADPVYKSFHSALHLIQTVT-THWQPDLWLVTRGANKIL-ENSLQPQQSLLWGLGAVINNEYPQMRCVCLDLSPTAEPDE---GEFLFKELH
TPSNELRLALRQGNRYGARLVSATI-PAQ--KQQLVSQEGAYLITGGLGKLGLLLAQWLSEMGASHLVLCSRNLKSPP--EAI---TSLA----KNGTQI
TVICADIASPTDIEEIFARFGQ-DLPPLRGVIHAAGVLDDGLLSNQNWQRYQNVMRPKVEGTLLLDRYTRDLSLDFFVTFSSAAVVLGSPGQSNYAAANT
FMDALMQQRQ-SLGLPGISINWGAWDTENEI-----KKRLAGWGIESMSAQTGFKYLSQLILANVSQSVIIIDWANF------------------QAAFN
L--NQMFFAEVIQPKEQQ----E---------------------KISAKILEKLNSV----YIDERTAVLTKEIEHVLRELTGLAIIPQKTSFLDLGLNS
LMVLEFKNSLERELGCNLPSSVIFDYPNLTELITYLQVE-----------
>tr|A0A0M4KKD6|A0A0M4KKD6_9DELT Polyketide synthase OS=Nannocystis sp. MB1016 GN=ncyB PE=4 SV=1
-WFLEQAWEAVA--PAKPG-RGRFLLLGAGGGLGAALRGLEAAGHAVVHA-VAGAPGAVPAGCWAFDDGHPAGLRALLADVFQGTG-PTAVVHLRSLEGD
DE--VADEVAEALARGCDSALHTVQALVGVESRARLWLVTRGAQAVV--APADVGQAPLLGLARVVAMEHPELRCARVDLDPARPGDE---AALLVKELL
ADAAEDEVAWRGATRQVLRLVRRAPGRSP--STWAPRADGSYVITGGLGGLGLATAAWLVERGARHLVLIGRAGVTSA--EQREAVAALE----LRGAQV
TVARADIAVREQVARVLAEV----TAPLAGVVHAAGVLDDGLLLQQDRRRLRAVMAPKIDGALHLDALTRGLPLDLFVLFGSAAGLLGAPGQGNYAAANV
FLAALAHRRR-ADGLAGLCVDWGAFAEVGLAAASADGERLAARGLRSLSPAEGLAALGRLLDAGVTQAAVVRQWAEF------------------FPAAA
TSA---MLSRLLTGPASA----R---------S------GD---G--EALRARLMGA----GAQARVVLLLERLREEAARVLRLPELAVETPLTALGMDS
LMGLELRNRIEAALGLRIPATLLWIYPTVTALAEHLAGL-----------
>tr|A0A0Q9PS62|A0A0Q9PS62_9GAMM Uncharacterized protein OS=Frateuria sp. Soil773 GN=ASG87_18855 PE=4 SV=1
-RV--YRWRELPFVRSISE-LGATVVAGAGGGV-AQLVALASRGVS--------------VSHWASITDAAIESLILVCDPITASGP-------------
---------MDDALVG---TFTELQALLGGNIARRVVILLPH----SRAAEADALLAARLGLSRALLHEYPEICWQVLDLPDGLDERT---VEGVVVA--
-------------------------SQQL--GEWQAEPNRTYLISGAFGGIGLRLCHWLLDHGARHLLLCGRSGRSLP--EQLR--AHAH----ALGAEL
RIEVADIGETHVREQLLTA-LA-GMPSLSGIFHAAGITDDGLLSTLNEKRVRAMLAAKCQGTRTLLDIAKSNGAALFVSFSSMSAHLGVPGQSTYGAANA
AMEAMTVAQG-GRHLCALSVAFGPWAEAGMAARLGSHDRAHAMGIRPLLPDQALASLGTLIQGGQSGVRLMFDWERF------------------ANAVP
----PCLLSQLPINDVPS----P--------RPH----NSP---DSLRALRHALASRE---TLADANEACLRYCVDVFAAV-TAQTIDVELAPVALGMDS
LLAIEIRRRLDRELGIHLEAATLLEIPSLRELAIYLLRQ-----------
>tr|A0A0Q2MA37|A0A0Q2MA37_MYCGO Polyketide synthase OS=Mycobacterium gordonae GN=AO501_21650 PE=4 SV=1
-LLYTLGWNEVPPPTAETA-DDTWLIAGFDE-----------------------LADVVPGSLRTNDIVDPERWVQLFAQAKDGGAPISGIVWRSGRRP-
------TEFAGRLEGELDQLLTLVRTALQQDLKGGLWVVTERAVATEG-EPVDPVQAALWGLGRTVIAEQPQLRCRLVDHDGSQDAVQW--LARLLAAPA
APVTEPELALRQGKFLVSRLLPWAR--------LAPRGDRTYLITGGLGALGLHTAAYLAQLGAGDIVLTSRHLPDA---EAQQAIAIIE----RYRCRI
HVFGADVGDESQVAELLNRIRA-ELPPLAGVAHLAGLLDDALLPQQSLERFRTTLAPKAFAAWHLHRLTKNDDLEFFIMYSSISGVLGSPGQANYAAANA
LLDGLVAERN-AQGLTATSVNWGPWAKGGMAASHAARVNLGAQGLIPLDPTAALSALGELFAEGTGQATVIANWQRT------------------AKVL-
-GGSRPAILDYVLPSAVA----A--------TQ------G------DSELLRQLHEI----PEGQRADFLTEYLQQEVQSFLRLAPPAATSRFLDLGTDS
LMAVELRNRLLGQFGGTISATAVFDYPTIRSLAEYLASQ-----------
>tr|Q9KIV3|Q9KIV3_STRAT 8,8a-deoxyoleandolide synthase 2 OS=Streptomyces antibioticus GN=oleAII PE=4 SV=1
-AMFRVEWVEEGSAGGA--GAGTWAVLGPRVPAAVRTMG----------------------TALDTPPQSLADLAA--L-----GDT--DVVVVTSLLSL
AS--GA---------------------------SRLVLVTRHAMTVASDPEPDLLLAPVWGLVRSAQAENPGRFV-LADIDGDEASWDA--LPRAVA---
--SAASEVAIRAGAVYVPRLARATD-------PAALDAEGTVLITG-AGTLGALVARHLVEHDVRRLLLVSRSGVAP------DLAAELG----ALGAEV
TVAACDVANRKALKALLEDIP--PEHPVTGIVHTAGVLDDGVVSGLTPERVDTVLKPKVDAALTLESVIGELDPALFVIFSSAASMLGGPGQGSYAAANQ
FLDTLARHRA-RRGLTSVSLGWGLWHEASGLTGGADRDRMSRAGIAPMPTDEALHLFDRATELGDPVLLPMLNEAAL------------------EDRAA
DGTLPPLLSGLVRVRHRP----S--------ARAG--TATAAPATGPEAFARELAA------APDPRRALRDLVRGHVALVLGHSAIDAEQAFRDIGFDS
LTAVELRNRLNAETGLRLPGTLVFDYPNPSALADHLLEL-----------
>tr|I0J6Y3|I0J6Y3_SORCE Polyketide synthase OS=Sorangium cellulosum GN=pelD PE=4 SV=1
-SVHEVTWRQVDPLPSFPP-QGAWLVFSDQRGVGAALKALSGVGQRCVRVFVGGGFERIEPDLYRIDPTKPGDYQRLLREALGEEGSCRGAVHLFSLDA-
------ETLSADLGRGSVSAAYLAQALVRHGFRPRLFLVTRGAQAVEG-EPVSVGQAPLLGLGKTIALEHPELRCTRIDLSAAGGEGE---AELLARELG
ARGREDQIALRGEGRYVARLVRGSFLRRE--AAIALRADRSYLITGGLGGLGLSLARWLVEQGARHLALVGRRGPGP---EAQQAIREME----EAGAQV
LVASADVSRRGEVERLFARVEE-RLPPLCGIVHAAAVLDDHTLLEQSEESFRKVFGPKALGAWHLHALSEGRALDFFVMYSSAASLFGSPGQGNYAAANA
LLDALAHERE-RGGLRSMSIQWGAFAEVGLAAAQDNGKRLSSRGGASFTPAEGLEALRRLLLNPRAEVGVVRQWLEF------------------YPGT-
--AGLPFLAEVMAEDASD----R--------GS------G----GPPLAL-ERLKSA----PAGERPALLERHLLEQAGSVLRL-KMDRGAPFQSLGMDS
LMSLELRNRLEASLGIRLSATILFTYPTAGALAEHLLER-----------
>tr|H2JD28|H2JD28_9CLOT Non-ribosomal peptide synthase/amino acid adenylation enzyme OS=Clostridium sp. BNL1100 GN=Clo1100_0890 PE=4 SV=1
-WFYVPQWVRSTPGYNCKSNSSQWLIFRDTLGISDEIKYFTKNGINVVTVTMGKSYERVDKKRFIIDPTQSGDYERLFNEITSTGITIGKIAHFWGVDSI
AEECQMGSFDCAQDAGLYSILKIAKALAKLEIHKEIRL-DVITNNVTGEEPTCPEKATALAASIVIPQEYSYIKSRCIDIVVPEGHKGSNLVHQLGAELL
SESPDRVIAYRSGFRWVMIYEQVKLEQQ-VNTEIPLKSQGVYLITGGLGGVGYALAEHIVKEYKAKVILTGRTVLEKLETPQEDKISNIRKLALEYGTIL
LFDASDASDEDKMKYIVDRAEEEFG-AITGVIHSAGVLDGSLINDLDLAECKTQFNSKVYGLLVLERIFRDKETDFCVLMSSIASVLGGLGHVAYSAANL
FMDYYVQKINSFNNKNWKSVCWSEWQKDGSNEKITIGATIAE---LSMSPDEAIDAFERILSFE-------------GQGQIVCSPGDLQQRLN--QWVK
PNHTDSGESEKSENIPKTYRPVLSNR----------------------Y--------------VEPQSQIEKELAEIWKDLFRISEVGIFDDFFELGGDS
LKAITVINNIYKKFEVELPLTDFFKFSTIEKLGAYLTAS-----------
>tr|Q4S1K1|Q4S1K1_TETNG Chromosome 6 SCAF14768, whole genome shotgun sequence OS=Tetraodon nigroviridis GN=GSTENG00025512001 PE=4 SV=1
ACFYHNELFVIPSEGNFQKGHIKAIVFEDKLGVAEGLRPYLHAESA---------LVENK-EYWT--ADE---LHRAVLCSCTS-ADIENVLFLWGVEDL
SRLSSEK-MLDSMVTCCQLFCRIVLALKDSKRSFTVRV---VTHRSSETTVRVSAGFVLSGLTRACAAEMVDLSFQLIDLASVTCE---D-IKMLAHVIH
TS-NLQEVTINKGELLTTRIERTDVTAGQSKSGPLFKQGCVYIVTGGLSGLGLETVKFIARNGGGCIATLSRSSLS---NEMQFEMESLRRRY---GVRI
LNVQCDVSVSMQVADAISNTKAFPFCPIKGVFHSAAVLHDAFIENLDASLFRKVLKPKVNGTLNLHRATLYKELDFFVCYSSISSFIGNPSQANYAAANS
FLDIFCHYRR-NLGLAGQSINWGPLNV-GLLFNKEFQRFLEAKGMMVMDVSDIHEALEKSLTLNRPQVICKFNFKNLNIHVLSQ----------------
---NASLRDRLAALVGSGLKDAD--TE----------------TC------------DTDTEL-ASSSHPRENVRSIVSDISSISKLNEDVSLHALGIDS
MLAMTLQNKIFQETGVNVPLVKILDPNTLANLESLVI-------------
>tr|A0A060WJC3|A0A060WJC3_ONCMY Uncharacterized protein OS=Oncorhynchus mykiss GN=GSONMT00048563001 PE=4 SV=1
SFFFHNELFTITDNTHVS-RKPKALIFEDILGVGTALRPYLHQTSF---------FVLNR-EFGT--NPQ---VRDLVSHSLGDAVDSQEVLFMWGVQDL
SHLSTEM-ALECLVDCCEHYRQIVLALKENECSCTIRV---ITYRSAETTVHVSPGFVLSGMTRACAAEIPGLSFQLIDLASVSSE---D-IQALVHVIN
TS-KHPEVMISRGQIYSTVIVRTPIK---SSEGTLFKKSCVYIVTGGLSGLGLETVKFIAHRGGGCIATLSRSPMS---AEMQLEMDTLQRRC---GVSI
MSVQCDVSVSGQVVNAITAIQMFPSCPIKGVFHSAAVLHDALIEALDRSHFNEVLRPKVNGALNLHYATQHNKLDYFVCYSSISSFIGNASQSNYAAANS
FLDTFSHYRR-NLGLAGQSINWGPLNL-GLLLNRDFQRFLEAKGMMIMEVSEVHEALEKCLLMNNPQVICKFNFRNLSNHVLSQ----------------
---NASLRGRLTALVEQELENTN--MT----------------EP------------IVQQ-----LSTAHENVRAMLSEITSVSIVNDDTALYALGIDS
MLAMTLQNYIFQERGVNVPLVKLLDPNTLSTLVTLLK-------------
>tr|H2LF10|H2LF10_ORYLA Uncharacterized protein OS=Oryzias latipes PE=4 SV=1
EYFYHNSFTIVPEGS-TASPPPKALVFSDELGISEGLKQHLDQESR---------YVSITHANHIV-NDG---FLSLLANLSTDIKNFDEALFLWYTEDL
TSLPPDCHLLQNLPNCCDVFRQIVVELRKFKFPHAIRV---VTYRSSDITVRISPGFVFAGLTRSFAAEMSDLSFQLIDMGMISPE---N-ITALSEVLR
KYPKFPELVVKDGKILRPSIVHSPLDFT-PTKKQFFKERAVYIVTGGVSGLGFETVKFISQRGGGNIVSLSRSKPS---AEVQQKMYALEKEH---GNCI
ASMQCDVSVFENLHMVITAIQKFPGCPIRGVFHSAVVLHDGIVEALNRSLYEKVFKPKVNGVLNLHHATQHCPLDYFVCYSSISAFLGNPSQSNYAAANS
FLDMFCHYRR-QLGLPGQSISWGALKL-GLLHNKELQHILEVFGIMGLELAEIRKSLEQCLILNRPQAVCRFNFKNISYNVFSH----------------
---NSSLTMRLYALVEEAVRKSR--QG----------------FF------------QT-K-QTN-LIPPREYITTLLSETLGLDKVRDESFLSALGMDS
MQAMTVQNLILQERSVSLPLVKLLDPTTLSTLVASLT-------------
>tr|A0A0P7ZBH4|A0A0P7ZBH4_9TELE Putative polyketide synthase 16 (Fragment) OS=Scleropages formosus GN=Z043_102245 PE=4 SV=1
EFFFESEINVTATENN-SSHKPKALVFADLQGVALALKQYLHDDSS---------YMDFKHDK-----EE---VLGLLLAL-DFSLDHEEILFIWGVFDL
TNLETEN-VMQRLLTCCECFRQLVLKLYEAKFSHPLRI---ITYGSSEKTVNINSGFVLPGLTRGCAAEFEFFKFQLIDIESISYK---D-IEALGQVIR
SYPKYPEIIISDGQIHSVTLSHTPFKDNHEKQKVRFQRNAVYVVSGGLSGLGFETVKFIAERGGGYIVTLSRRKPT---HETQLVIDSLQSTY---RITI
LCQQCDISITSQVEEAFSDIKKFPH-PVKGVFHSAVVLSDGLISTLNESLFEKVLKPKVNGVLNLHRVTRKSKLDYFVCYSSIASCMGSAAQSNYCAANS
FLDLFCHYRR-RMGLAAQSINWGPLNL-GLLLNKDLHTFMESKGVTPMSISEAHESLEQSLLLNSPQIVCKFSFKNLAA--SRQ----------------
---NDSLRQRLYGVLETVLQTAM--EP----------------DP------------RVEMVNSSLTSAPEEYIRLLLCEICDAELLEDNVLLTTLGVDS
MLVITLQNHIYWERGISIPLVKLLDPQTLSTLISYLK-------------
>tr|F6ULR9|F6ULR9_MONDO Uncharacterized protein OS=Monodelphis domestica PE=4 SV=1
DFLFENKWKPISPVPVHSMDSPPFLVFADKFGIAQQLKKYLHSQSK---------YITSEEWEAMQ-NSE------ESGKDRKKEEGFHDVLFMWGIQKF
SEETPGMLITKYSAKCCETFSQVILALRGKNAPCSVTI---ITHRATSRNIQISPGPVLSGMTRCCFVEVPDITFKMVDISFPSTQ---D-IASLAEAVI
KYKDYPELWIDQGRMYISEIRRTPYELPLAAEKKLFKSNAVYIVSGGLSGLGFETVRFIAQKGGGSVVILSRRSPN---AEQQLEIQSMEKQNE--GCKI
ISLQCDVTVHSEVNKVISSINIFPKVPIKGVFHSAVVLDDAHLEALNVSRFEKVLSPKVAGVINLHYATRGHKLDYFVCYSSVTSFLGNATQANYAAANS
FLDMFCHYRR-NCGLAGQSINWGALNL-GLLLNKDLQKFLASKGILTLQKSEIYEYLEKSLLLNNPQAVVKFDFKALKNYFFSQ----------------
---VPSFKIRFAKFLQNEYNAVA--EP----------------N-------------SMAH-QDSSAMATQDYIYSLVSELSNINPITMNTPLMSLGMDS
MSAMTLQNRLFQDKKVDVPLIKLLDPNTLMTIQSLLE-------------
>tr|M4A1P6|M4A1P6_XIPMA Uncharacterized protein OS=Xiphophorus maculatus PE=4 SV=1
EYFYHNDFSIIPESS-TSSKPPKALVFSDHLGISKALQPHLDQESR---------FVSFTHAKDIL-SNG---FPSLLSNLSANIKNFNEVLFLWGKEDL
TSQSPDA-VLHNLASCCEIFRQIVQELKRIQFPKAIRA---VTYRSSDITVHISPGFALAGMVRSFAAEIPDLSFQLIDIGSIFTE---D-IKALSEVLR
SHPKYPELVIKDGLILKPSIVRTPLEVT-PVKKQLFRKRAVYLVTGGLSGLGFETVKFISQRGGEYIVILSRSKPT---AEVQQEILNIQQQY---GNSI
TSMVCDISVSERVQKVILEIQKFKGFPIKGVFHSAVVLHDGLIETLNRALYEKVFKPKVNGVLNLHHATKHCHLDYFVCFSSISAFLGNASQTNYAAANS
FLDLFCHFRR-KLGLPGQSISWGPLNL-GLLLNKEFHRFLEAKGMMLLDVVEVHKSLEQCLILNRPQAVCRFHFRIIRYNILSQ----------------
---NKALSLRLSVLVNEAFQNFK--EE----------------ES------------KT-E-QSD-SVSPKEYVFSLLSETIGIDQLSDDSPLTSLGMDS
MQAMTLQNMMFQERGVNVPLVKLLDPNTIWTVVTILS-------------
>tr|H2MBT4|H2MBT4_ORYLA Uncharacterized protein OS=Oryzias latipes GN=LOC101169644 PE=4 SV=1
EYFYHNTYTVASEKV-ASCSPPKALVFSDHLGISEGLQKQLDQESR---------YVPVTHAKDIL-TNG---FSSLLANLKTCIKNFDEVLFLWGKEDL
TSLKADT-VLHNLASCCEVFRQIVLKLKQIQFLKSIRA---ITYRSSDITVHVSPGFAIAGMTRSFAAEIPDFSVQLIDVCSVSSE---D-IAALFEVLR
SYPKYPELVVKDGQIFKPSIVRTQPEVT-PAKRQMFRRRAVYIVAGGLSGLGFETVKFISQRGGKHIAILSRSKPT---PDVQQEINNVEKQC---GNRI
KSLECDISIFEHVHDALTTIQMFPGCPVRGVFHSAVVLHDGLIESLDRSLYEKVLKPKVSGVLNLHHATQQCQLEYFVCYSSISAFLGNASQTNYAAANS
FLDMFCQYRR-RIGLPGQSINWGALNL-GLLLNKEFQRFLEAKGMMVLDVAEIHKSLEQCLLLNQVQAVCRFHFSNIRYNILSQ----------------
---NKALTMRLSALVEEAFQKSR--EV----------------DP------------QL-R-ETK-AVSPKEYMFSLLCETVGVDLLREDSLLSSLGIDS
MQAMTLQNLIFQERGVNVPLVNLLDPSTFSTVIALLS-------------
>tr|G3NMY1|G3NMY1_GASAC Uncharacterized protein (Fragment) OS=Gasterosteus aculeatus PE=4 SV=1
EYFYHNTFSVIPEGL-TSAPPPKALVFCDRIGISSALQPFLDSRSS---------FVSFTNEKDIL-SHG---LPSLLANLNTALKNFDEVLFLWGKEDL
TSLPAED-VLQICASCCETFRQIVLELKRICFPNSVRA---VTYCSSDITVHISPGFALAGMTRSFAAEIPDLSFQLIDIRTISAK---D-IAALVQVLR
SHPKYPELVVKDGLILKPSIVRTPLEIA-PTKKQLFRRRAVYIVAGGLSGLGFETVKFISQRGGGYVVVLSRSKPT---PAVHLEMHNVETQC---GNCI
TAMECDVSVSESVHDVVDAIRKFPGCPIRGVFHSAVVLHDGLIETLDRSLYQKVLKPKVNGALNLHHATLRCQLDYFVCYSSISAFLGNASQTNYAAANT
FLDMFCQYRR-KLGLPGQSINWGALNL-GLLLNKEFQRFLEAKGMMVLDVAEIHKSLEQCLVLNRPQAVCRFHFRNIRYNILSQ----------------
---NAALTMRLSALVDEAFQKSK--EQ----------------DS------------RT-K-ESE-SVSPRDYVVSLLCETIGVDRLKDESPLSSLGIDS
MQAMTLQNRIFQERGVNVPLVKLLDPNTLSTVVLTLS-------------
>tr|A0A087XTQ5|A0A087XTQ5_POEFO Uncharacterized protein OS=Poecilia formosa PE=4 SV=1
SLFFHSETVALAEERDVDGSKIKAIIFEDHMGIAKGLRPYICTDSV---------IVGIR-KKLS--ADE---VKCLVIHSLSN-DNLKKVLFIWGVENL
THLSSEM-ILESFVTCCETFRHIVLSVKETKRLCAINV---ITYRSTELTVHVSPGFVLSGMMRSCSAEIADIHFQHIDLASVTSE---D-IQTLACVIK
TK-QQQDVRISKGQASTTRIAQTPVKDSRTKPARLFEQRCVYIVTGGLSGLGLETVKFIAHNGGGCIAVLSRSVPS---DEIRFQLDLLQKRS---GVSV
LNIQCDVSESKQVVDSITKIGRFPSCPIKGVFHSAAVLHDSLIESLDESLFRKVLKPKVSGTLNLHFATLHNKLDYFVCYSSISSFIGNASQCNYAAANA
FLDTFCHYRR-NLGLAGQSINWGPLNL-GLLLNKGFQKFLETKGMMTMGVHEVHKTLQRCLVMNRPQVICKFNFKNLSLHVLSQ----------------
---NPSLRERMATLVETAIKDEI--HK----------------TP------------KVQH-----SFTAYETVRIIVSEMLNIDAVDDDSCLSALGIDS
MLAMTLQNKIYQETEINVPLVTILDPNTLTTLVSFVQ-------------
>tr|H2MBT8|H2MBT8_ORYLA Uncharacterized protein OS=Oryzias latipes GN=LOC101169887 PE=4 SV=1
SLLFHNESVPVGLQTDLENCKIKAIVFEDKLSIAKGLKPYLSPESV---------LVEGKG---KLTADK---VRDMVLDSLSN-EALTDVLFLWGVEDL
THLSAEM-MLNSLVTCCEFFRQIVLAVKESKRSCTLRV---ITHRSTEMTVHVSPGFVLSGLTRACAAEVVDLSLQLIDLAFVTSE---D-IQVLARVIR
TC-KHQEVRISNGQIWGTSITQTQVKIEHKRPEKLFKKKGVYIVTGGISGLGLETVKFIACNGGGCIATLSRRILS---EEMQFEMNLLQKRF---GVSI
IHIQCDVSSLVQVVNAISEIQRFPSCPITGVFHSAAVLHDALIPSLNEDLFRKVLQPKVCGVLNLHHATLHNKLDFFVCYSSISSFIGNASQCNYAAANS
FLDAFCHYRR-NCGLAGQSINWGPLNV-GLLLNKEFQRFLEAKGMRIMSLHEIHETLRMSLVMNRPQVICKFNYRNLHHHVLSQ----------------
---NASLRERLSVLVAARLKDG----S----------------EP------------KVQP-----LSSTRQRLRTVISEMLNTRELEDDASLCALGVDS
MLAMTLQNKIFQETGVNVPLVLILDPSTLTSLEEFVH-------------
>tr|E6ZJA9|E6ZJA9_DICLA MxaC OS=Dicentrarchus labrax GN=MXAC PE=4 SV=1
SRFFHNEIIAIPDKRDLQKGQIKAIVFEDKLGIAKGLRPYIHPESA---------FVESR-QDWM--ADQ---VRNVVFHSLTS-VDLENVLFFWGVEDL
SYLSSEK-ILDRLVTCCELFRQIVLALKENKRCYTVYV---ITYRSTETTVHVSPGFVLSGMTRACAAEMMGLSFHLIDLASVTNE---D-IQMLVHVIN
SC-NQQEVMISKGHASTPRIVRTPMSYRPTRPGQLFKQRCVYIVTGGLSGLGLETVKFIARNGGGCIATLSRSTLT---EEMQFEMELLQRKY---GVLV
MNVQCDVSVSMQVVDAVSQIQRFSSCPIKGVFHSAAVLHDALIETLDQSLFEKVLQPKVSGALNLHYATLHSKLDFFVCYSSISSFIGNPSQCNYAAANS
FLDTFCHYRR-NLGLAGQSINWGPLNL-GLLLNKDFQKFLEAKGMMIMDVCDIQEALEKCLLMNRAQVICKFNFKNLNIHVLSQ----------------
---NASLRERLSALVEIELKDDI--SN----------------EP------------TV-H-----LSSTHGSVRTFVSDISNVSVLDDDSALCALGIDS
MLAMTLQNKIFQETGVNVPLVRILDPNTLATLETIVM-------------
>tr|A0A0Q3S445|A0A0Q3S445_AMAAE Putative polyketide synthase 1-like protein OS=Amazona aestiva GN=AAES_187730 PE=4 SV=1
ELMFENKWKEISLSQINRGAMPRVLVFADKFGIAEKLKKYLHPDSR---------YIMYEDWEXLL-EGH--------TQNKRAEENYDEILFLWGIQKL
NERFPSKVVDX-LSKCCEAYRQVIVALREKMSRCSVRV---ITYRTTERYVHVNCGFALYGMTRACIVEAPEIXFQMIDLSSASSL---D-ISVLADVLV
KHKEYPELCIXQGRTYIAEIRRTPFVDAGESQ-KLFKPNAVYVVVGGLTGLGFETVKFIAKNGGGCIAIFSRKMPS---NEKQEEMKALQEQYK--EIKV
LFVQCDVTSTNDVEKAFQSVSIFAGNPIKGVFQSAVVLHDGRLEVLKLADFQKVLSPKVAGTLNLHWATRGQQLDYFVCYSSVTSFLGNSTQTNYAAANS
FLDIFCLYRR-NCGLSGQSINWGALNL-GILLNQNLXSILESKGIDILQVHEIHEYLRKSLLMNNPQVVAKLNYQTLLHHVFSQ----------------
---ITSLRSRFLSFLSEEYRNKL--ET----------------SE------------KIQV-EDAALIKPEDYIISLVTELTNLSPLTMNTALSSLGIDS
MLAMAIQTRVFQERKVNIPLLKLLDPHTLSNLVVVLE-------------
>tr|W5L5F9|W5L5F9_ASTMX Uncharacterized protein OS=Astyanax mexicanus PE=4 SV=1
EFFYHTDFKVNSENQNPKTPFPKALVFADHLGLAEALKKHLAPTSK---------YLSFKHAEELL-HEG---FQALMLKLNSDVKPFDEILFIWSDTNL
TTCSADR-TLETMVNCCEVFRKIVTALKSGSFPHSIRT---VTYRASETTVQVTLGFVLSGMIRACAAEVSELLFQLVDISSVSSQ---D-VAAFAQVLK
SYPKYPELLVKDGQVLKSNIVRTSLRNSQLGAKQLFQKRSVYIVTGGLSGLGFETVKFIAQRGGGHIVILSRSAAS---PEMQQEISTVKNQN---DVEI
LSLQCDVSVIRQVEKVISVIQTFPMCPIKGVFHSAVVLHDGLIESLNRALYEKVLKPKVCGALNLHHATRHCKLDYFVCYSSISSFIGNASQSNYAAANS
FLDTFCHYRR-NIGLAGQSINWGALNL-GLLLNKDFQRFLESKGMAIMEVNEIHQCLQECLLLNRPQVICKFNFRNLRTHVLSQ----------------
---NASLRMRFSALVQEAFRNDQ--IA----------------EL------------ET----TKSKSSPHEYVRSVLCNTLGVKELSEDMTLADLGVDS
MLAMTLQNLFAQEKGVNIPLVKFLDSSTLAALAAVVA-------------
>tr|W5ML50|W5ML50_LEPOC Uncharacterized protein OS=Lepisosteus oculatus PE=4 SV=1
EYFFHNELTAISEDFNSS-HRSVALVFADQLGVAQALRQHLHHSCT---------YIPFQ-DSGKFADRE---LPALI--SQHVPRQYKEVLFLWGIQNL
NNLTTEE-VLECLVCCCEVYRQIVKTMKEKKSPNVIRA---VTYRSTENTVHISPGFVLSGMIRSCAAEIPGLTFQLIDIGSVSSE---D-ITALAQIIN
SHTRYPEVVISKGQIFTTEITRTAIKNVQETEKQLFQQNSVYIVTGGLSGLGFETVKFIAERGGGCIAILSRSAPS---AEKKIEITDLQNHF---GVSV
ISLQCDVSVSEDVMKAITDIQRFPSCPIRGVFHSAVVLRDGLIDILEKSHFEKVLRPKVNGVLNLHYATRYCKLDYFVCYSSITSFIGNSAQTNYAAANS
FLDVFCHYRR-NLGLSGQSINWGALNL-GLLLNREFQRFLEAKGMMIMEVPEIHECLEHCLLQNNAQVVCKFSFKNLSNHVLSQ----------------
---NASLRMRLLALVTEELKNTR--ET----------------EP------------QVEE-S-TLASSADEYVKSLLCEVGNVDVMRSDTGLSALGIDS
MLAMTLQNRIFQDRNVNVPLIKLLDPSTVSSLVLVLQ-------------
>tr|W5K168|W5K168_ASTMX Uncharacterized protein OS=Astyanax mexicanus PE=4 SV=1
EYFYHNSYSIATEYDGISSLLPTSLVFADHVGIARGLQPYLDESSK---------CISPTKTKALL-EQQ---FDSLLSELKPNFTHFAEILFMWGSGDL
TSYKTEN-VLDCMSTCCEILRKIVAGLKAMSFQNSIRV---VTYRSSEDTVYISPGFVLSGMTRACAAELPDLSFQLIDMSSVSVD---D-IKALAKVLK
SYPKYPELVIKDGQILKPQISHTTGINTQPKAKKLFHKNSVYIVTGGLSGLGFETVKFIAQRGGGTIVILSRSAPS---HLMEQEINHVKNQC---QSLI
TCLQCDVSVSEHVHQVVAQIKQFPSNPIKGVFHSAVVLHDGLIESLNKSLYEKVMSPKVNGVINLHHATKRCNLDYFVCYSSISAFLGNASQTNYAGANT
FMDTFCQYRR-NIGLPGQSINWGALNL-GLLLNKEFQRFLEAKGMMILEVTEIHESLEQCLLINKPQAVCRFNFKNIRYNVLSQ----------------
---NKALTMRLSALVEEAFKKAK--VV----------------DS------------SSKQ-TTNPVSSPKEYIKSVISETIGVEKLTEETPLSTLGLDS
MLAMTLQNLIFQEKGVNIPLVTLLDPDTLSGLVKMFG-------------
>tr|U3JAJ7|U3JAJ7_DANRE Uncharacterized protein OS=Danio rerio GN=si:dkey-61p9.11 PE=4 SV=1
EYFFHNSFDIISEDD-MLDTQIKALVFSDQLGIFKALQQHLDSRSR---------CVSFSDSSTLL-EGG---VETLLSKLASSVKNFQEILFMWSDADL
TTLESEK-VLESMAGCCEMFRKTVRYLKALQFPGVIRV---ITYRSSESIVSINPGYVLTGMTRACAAELQELSFQLIDMGSGTSE---D-IKALVQVLR
SYPKYPELVVKEGNILQPEITHTPLPSMQPK-NNLFKKKSVYIVTGGLTGLGFETVKFIAQKGGEHIVILSRRNPN---PEMQQEISQLSSRC---GSVI
KSLPCDVSVSEQVDQTIAKVKLFPSSPIKGVFHSAVVLHDGLIERLDKSLYEKVMRPKVNGVINLHRATIQCNLDYFVCYSSISAFMGNASQTNYAAANT
FMDTFCQYRR-NIGLAGQSINWGALNL-GLLLDKVFQRFLEAKGILLLEVPEIHESLEQCLLINKPQVVCRFSFKNSWNSVLSQ----------------
---NKSLNARLFKIAKEAFIRAG--VN----------------PS------------RPEQ--PMTSSSPHDYLRFLISETAGVEKLSDDVHLFELGIDS
MLAMTLQNHIFSYRGVNIPLVTLLDPNTLSTITKILE-------------
>tr|W5K186|W5K186_ASTMX Uncharacterized protein OS=Astyanax mexicanus PE=4 SV=1
SYFFHNERLAVQASSNIC-SKPKAVVFEDTLGIASALKPYLHPSSV---------FFSPADANWSTSPAE---L--------QVANGAEKVLFVCSFQNL
SHLKPQS-VLEHLVDICELYRQVVLVMRKCKHLLTIHV---VTYRSSENTVHISPGFVLSGLTRACAAELSEISFQLIDLGTVSTE---D-IEALVYVIC
SYKEYPEVMIRKGQVYSTVITRTPINTTKPKTKHLFTQKAVYIVSGGLSGLGFETVKFIAHSGGCCIATLSRNAAN---EETKLQISRLTKRY---GVKI
LTLQCDVSVSEQVLEAITIIHKFPSCPIKGVFHSAAVLHDGLLETLDKSIFEKVLRPKVNGALNLHYATVNSKVDYFVCYSSISSFIGNASQANYAAANS
FLDTLCHYRR-NIGLAGQSINWGPLKL-GLLLNKGFQTFLESKGLMIMEVPEIHEALKHCLLENRPQVVCKFNFRNLRNNVLSQ----------------
---NASLKGRLTALVEKELESKL--VN----------------EP------------RKN-----LQSSFDEYIRCMLSNICNVDALEDETVLATVGIDS
MMAMTMQNRMFQETGVNIPLVALLDPNTVSSLISLFT-------------
>tr|A0A060WJB8|A0A060WJB8_ONCMY Uncharacterized protein OS=Oncorhynchus mykiss GN=GSONMT00048557001 PE=4 SV=1
EYFFHNDFSVVSDDY-KPINKPKALVFADQIGVSEAMQKHLSSQSQ---------YISFTHANDLL-SRG---FKALLSKFKSDL-SFAEILFVWSNDNV
TSHETEA-ILENMVNCCEMFRQIVLELKAMKFPNSIRA---ITYRSAENTVRISAGFALSGMTRSCAAEMSDLSFQLIDISSVSTE---D-IRALSQVLD
SFPQYPELVVKDGQILKPYIVHTPTESS-PKPNQLFQKNSVYIVTGGLTGLGFETVKFIAQRGGGYIVILSRSSPS---TDLQQEISNIESQS---GATV
VSLQCDVSISAQVVNTVIAIERFPSCPIRGVFHSAVVLHDGLIEILDKSLYEKVLKPKVNGALNLHHATKLCKLDYFVCYSSISAFIGNAAQTNYCAANS
FLDTFCQYRR-NIGLAGQSISWGALNL-GLLLDKDFQRFLAAKGMMVMGVAEIHESLEQCLLLNRPQVVCKFSFKNLMRHVLAH----------------
---NASLNIRLGALVDEGITKEK--GE----------------VA------------GYDQ-TTV-SMSPSDYVKSVLRETLGVENLNDDSSLTALGIDS
MLAMTLQNLLFQDRGVNVPLVKLLDPNTLSTLVAMLK-------------
>tr|A0A060WRM8|A0A060WRM8_ONCMY Uncharacterized protein OS=Oncorhynchus mykiss GN=GSONMT00048561001 PE=4 SV=1
EYFFHNDFRVVSEDI-KSSQARKALVFSDQVGVSKAMQPHLSSMSK---------YIPFAHAKEFL-NHG---FPTLLANLNSDIKNFEEVLFMWGEEEL
TSVKTET-VLENIVNCCEIFRQLVLELRASNFPNSIRV---ITYRSAENTVRISPGFALSGMTRACAAEMADLSFQLIDISSVSTE---D-IRALSQVLK
SYPKYQELVVKDGLIFKSDIVHTPMESIQPKPNQLFQKNSMYIVTGGLTGLGFETVKFISQKGGEYIVILSRSSPT---PDIQQEICNLEKQY---GAHI
ICMGCDVSVSEHVLRAIGLIKKFPSCPIRGVFHSAVVLHDGLIESLDKSLYEKVLKPKVNGALNLHHATKHCKLDYFVCYSSVAAFIGNVSQTNYAAANS
FLDIFCHYRR-NIGLAGQSINWGPLNL-GLLLNKDFQRFLEAKGLMVMDVTEIRESLEQCLQLNKPQAICKFNFKNMKYNVMSQ----------------
---NASLTMRMTALVEEAMQKDK--LK----------------ES------------RSGH-NAA-SSSPSGYIRSVLSETIGVDKLNDDSPLSALGIDS
MLAMTLQNLIFQERGVNVPLVQLLDPNTLSTLISNLM-------------
>tr|C3ZIP9|C3ZIP9_BRAFL Putative uncharacterized protein (Fragment) OS=Branchiostoma floridae GN=BRAFLDRAFT_247081 PE=4 SV=1
DLVFTTTWTPAQSQWGNEFCELKCLVLQDDCGISNQLEPFVSSDSV---------FISLEDFKRTDYRNDERAFPKLLQEM-DVN-NFDFVLHCCGISQL
DPEKLDAEALTRVELACASLRQVMKMLITDGSRVPVKI---ITRNVQFSDVSDLAGAPLWGLIRCAIREGAYPLLQLVDLSSGNNF---E-IYTLLHELV
ARESYTEIMCVQSAKYYLEIVSSTLRSEQCGRKALFRRDASYVIVDGLTGLGFFTIEFLAERGAGNIVTVSRTQPQ---ADTVTELRRVGEKY---GSKI
ICLVADVTSYKSMTAALDKLDCLPGIPLKGVFLSTAVSSDRILINQSHAQFKMGLDAKVVGTWNLHLTTRHLNLDYFVCYSSMSSVLGTGGQTSYGAANA
FLDGIACLRR-QMHMVGQSINWGALQL-KTLHRDKMAKILEQNGIRDLYKDRVSECLENCLLLNPVQIVVDLDRSRLAA--MTK----------------
---RFPDVRRFEKLVGDIDDVTA--DD----------------VM------------LS--TAQGRREAIGALTRNVFVNLLNAEPVTMQRSVVNMGMDS
LLALTAQNIFKNKFQVDVPWIALLGKKTIESINDQVF-------------
>tr|C3YVH3|C3YVH3_BRAFL Putative uncharacterized protein (Fragment) OS=Branchiostoma floridae GN=BRAFLDRAFT_205831 PE=4 SV=1
DMFYTTSWTGYSSDWKNKTCHLRCLVLEDECGIMDHIKPLVSSESV---------FIPLQDIESIDYKNDEQALQKMLQVN-NVNADVDLVLHCCGISLL
EAETTDTESLARIQLACASLRQLIKMAVASGQTIPLKV---VTRNSSV----DLAGTPLWGLVRCAIREAAYPSLQLVELSRGDHW---E-THTLLHELV
TGESYTEIMFVRSKKYFLEIQSSTLHAEQCTRQTLFRKDASYIVVGGLTGLGFLTVRFLAERGAGHIAIMSRSQPK---QDVVAELKTLEETF---GARI
IYLQADVSSYDSVNSALEELISFPRIPLKGVFHSAVVISDGVLINQDHVQFQRGMGAKVSGTWNLHLATRHLNLDYFVGFSSVSSVLGNGGQTSYGAANS
VLDGIVHLRR-QLGLSGQVINWGALQL-GLLERDRVAKFLEQIGILPIDKDCICESLETCLIANPSQTVVNLDRPKFRQ--FLQ----------------
---ELPDFKRLEVVLGGPAESSP--DD----------------TA------------VVKMDKRAQQKSLGDFTRLLFVKLLSAEDVNMYTSIVNLGMDS
QLALNAQSIFRKQLNVDVPVVALLSQETVQSISDLV--------------
>tr|A0A0Q6Y750|A0A0Q6Y750_9BURK Uncharacterized protein OS=Rhizobacter sp. Root1238 GN=ASC98_22085 PE=4 SV=1
GDVYELQWVAATDGSLATEATGDWLLLSDDTGVAAALRASLQRHGGRCTEVVGERFQRLASNRWSVDPRDAAQMQSVVTDWR-SH-TPRGVVALWSLDTP
GADPRD---AAAELRASGSLLHVLQALAADAEPVALWL---VTRGAQAVGPESSAAAGAWAFLGVLAVEHPDIPLRAIDIDATGIEALA--------ELL
S-SPRPRVALRGPTRHEPRLARRHAPSTQGRVSFEVRPDASYLVTGGLGALGLHTARWLQRAGARQLALLGRHAPS---AEAQQAIHEIEAA----GTQV
RCFAADAGDGAALQRVLETVREMA--PLRGIVHAAGTLDDGIALRQQWPRCAAVLHGKARAAQHLHELTRTLPLDFFVMYSAAGLLLGAPGQCAYAAANA
ELDALAQMRR-AQGLPALSVAWGPWAQGGMATQLAGHDPWRDRGLLPIEPAHGFERLEQLLRDGAVHAVLTIDWQRFIATL---P---------------
---AGVDAA----FFDGVLPRAS--TP----------------APAAA-------DASPATPSGRRAAALAAHLTERALQVLGLEPPDPKTPLKDLGLDS
LMAVELRNALTRSIGRPLSATLLFDYPTVAALTAHLM-------------
>tr|A0A062U1G3|A0A062U1G3_9RHOB Uncharacterized protein OS=Hyphomonas sp. T16B2 GN=HY2_01100 PE=4 SV=1
VELYTTDWHPIELQS--AKVAASWLIISGDHQ---ELAKALAA-GKDNAR--IIS-------------AADPEALDKALDWL-STPEPRQVLDLSSLDTD
DA-IAV----------IKTGLAHVQCV--ASRSIRYAS---ISQGAFQTGQHSISGRALQGFVSTAALEHPELEIHCLDIDPDTDEGHEQ-VSEAVCGAV
S-AGPVKLALRDGKWFAPRLAPAKQLE-EPRRKPVIHADGSYLITGGLGGLGLYTAKWLASQGAKHIVLTGRSAPD---EKAKNMITEIEAT----GASV
HVFQADIGDKDAVAALLATIDTLP--TMKGIVHAAGALRDGPVMTRTPEDVDIVVQGKLRGAMFLDQMTRDLSLDFFVLYSAAGASLGAPGQSLYAAANS
GLDALAAARR-RDGFAALSVAWGFWSNAGMGARLAGRDTWSTRGLGAITPENGFPAMATLLASGNPAMAAKVDWARFLETA---P---------------
---KDIDLS----MFDGLSRDTG--LA----------------ASNTP-------SSSASLSREAIKVELRRITESAVRSIIGMDEEGRAEPLKDLGLDS
LMAVELRNDLARTLGLRLSATLLFDYPTIDRLCGYLA-------------
>tr|I4MQ95|I4MQ95_9BURK Polyketide synthase OS=Hydrogenophaga sp. PBC GN=Q5W_1772 PE=4 SV=1
ELLYHVHWQALPAAG-REPVAGRWLLLADRGGVGDALAAQLQQQGAHGTVLAGDALDAVAQ-----------------------G-PWRGVVHLWGLDTP
SFADAATPDLSDDWPALGSALALAQ----ALVPAPLFL---VSRGACVVVGEQPRAAGLDGLVSVIEQEHPELRARAIDLDPADSAVQAD---RLLAELL
A-GVPSRLALRGARRFAPQLRRPTADAAQT--AATVRADASYWITGGLGGLGLETARWLVAGGARHLVLSGRRAPD---EHAQSVIAELRAQ----GATV
RAVEADAADGARMQAVLEEIRDMP--PLRGVVHAAGALDDAVLQRQTWPRAQAVLRGKAQGAWVLHHITRDRPLDFFVLYSAAGLWLGAAGQGLYPAANA
RLDALAQARR-RAGLPALSVAWGAWGGVGMAARGAGHDAWGARGLRPITPATGFAALARAMREDAAHLVLAIDWPRFLAQR---P---------------
---GAADSE----LFRAVAGGAG--PT----------------ATAAS-------APTPGLPSGQRRAALVAYLGERTLQVLGLDAADPRAALKDTGLDS
LMAVELRNALAKAFAQPLPATLLFDYPTLDALAAHLL-------------
>tr|A0A059G3R7|A0A059G3R7_9RHOB Beta-ketoacyl synthase OS=Hyphomonas oceanitis SCH89 GN=HOC_15547 PE=4 SV=1
VKLYTTSWKAESRDGEPNDHAQSWLVISDEKLG-EELAEALAD-IAVCAR-MVRS-------------EAAPSEFNAALDWL-ADPEPRQIIDLVGLARD
LDASEH----------VIRTLRHTQAI--AKSSTSLAI---LTQGAFATENLSISGASVQGFIATVSLEHPELSIRGIDLDPAVNNYDKE-LALALSAQL
S-RGSAKLAMRGTEWLSPRISPANLSD-EPRLTAPVRTDATYWITGGLGGLGLYTAQWLANSGAQHIVLTGRRSAT---ESAKAAIAEIEKS----GAIV
HVLKNDVGDDTSNAQVLALINTMP--PLRGIIHAAGTLRDGPALTREPEDVESVFRGKFQGACSLDRQTRELPLDFFVCYSAAGTILGASGQTLYTAANT
ALDALIVKRV-REGYPGSSIAWGGWSGAGMLAGLSAREGWAERGLVDITPDSGFPQLEQALQSGIPNIAVAVDWRMFTATA---P---------------
---SGLDLG----PFSELTHSSA--IA----------------SLSA--------GRIPTATPSERRAKLQQCVETAARDIIGLDSPDPDHPLKDMGLDS
LMSVEMRNELSRGIGLRLTATLLFDYPTVNRLIEYLD-------------
>tr|E0UL81|E0UL81_CYAP2 Beta-ketoacyl synthase OS=Cyanothece sp. (strain PCC 7822) GN=Cyan7822_5857 PE=4 SV=1
DWLYQNTWQPQPPVSD--ETANRWLIFSDQSHLGQQLIAQLQQQGHDCVIAAGSTYQLLAQNLYQVNPSNPEDFQRLLAESLD-NAAYGGIIHLWNAENC
SENPPDLALLAAQVKACASVLYLVQALAKANMASRLWL---VTRGSQAVD--NVEQASLWGLGGVIAMEHPALHCTRLDLAPTPE-T-EE-VQNLLKEFA
ASS-ETQIAYRQNSRFVLRLERYRMDEQE-KRENLINSESSYLITGGLGALGLKVAEWLIEG-AKSVILVGRQHPS---DIAQAKIAQLEAS----GAKV
VTMQADISNAQAVDHLITTIASMP--PLRGIIHAAGVLKDGLVTGQTWEQFIEVMKPKVMGSWILHQSTRDIPLDFFVCFSSIASVLGSPGQSNYAAANS
FMDMLAHYRR-SMGLPALSINWGPWSEGGMTTGLSDQERWAAQGLNLISPEQGLKFLEKLLKQDAAQAVMPINWTKFLAQF---P---------------
---YNQIPSFYETFVQ----SSQ--PK----------------Q-------------AQSVAPKERQSLLKSFIRLQVAQVLGFSSSDVQQGFVELGMDS
LMAVELKNRLQNNLGLAISPSLAFDYPTVAALTDYLL-------------
>tr|A0A0Q3XMK0|A0A0Q3XMK0_ALLMI Uncharacterized protein OS=Alligator mississippiensis GN=Y1Q_005996 PE=4 SV=1
DLMFENNWKEIFPVQSYSGEAPRVIVFADKLGIAQLLKKYLHHKSR---------YVMYEDWEIFL-EAK---KPEMTAEHKKTEEGYCEVLFMWGIQKL
SEELPGKLVAQ-LTKYCEAYRLIILALREKKSKCSVRM---ITYRTTEKNVHINPGFALCGMTRTCIVEVSEIMFQMIDISSSSML---D-ITALADVIV
KCKDYPEIWINQGRIYTSEIRRTPFKDVNEAEKKMFKQNAVYIVVGGLTGLGFETVRFIAQNGGGSIAIFSRRSPN---KEKQKEIKALQDQYE--GSKI
VSLQCNVVSASEVERAVQSVKIFSKRPIKGVFHSAVVLHDGHLEVLNMSHFEKVLSPKVAGVVNLHCATRGQELDFFVCYSSVTSFLGNSTQANYAAANS
FLDMFCHYRR-NSGLSGQSINWGALNL-GILLNQNIQNILESKGIDILQVHEIYDSLKKSLILNNPQAVIKLNFGTLTNHVLSR----------------
---IASLRSRFTTLISEEVGNQH--QL----------------SE------------QSAP-KNVSLIKSEDYVISLVSHLMNANPLTMNTSLVSLGMDS
MLVMTLQNRIFHERRVDIPHLADIPERHAVAFGLVLC-------------
>tr|M7AJV2|M7AJV2_CHEMY Polyketide synthase PksN OS=Chelonia mydas GN=UY3_18267 PE=4 SV=1
DLLFENKWKEIFSPQTSLGEAPRVIVFADKLGIAQQLKKYLHNESR---------YVMYEDWETLL-EAK---SSEMTAQHKKREEDYQEVLFMWGIQKL
NDEFPSKVVAH-LAKCCEAYRQIIVALREKKSSCSVRI---ITYRTTDRNVHLNPGFALCGMTRTCITEISGIIFQMIDISSSSTL---D-ISVLADVIV
KYKDHPEILINQGRIYTSEIRRTPFKDVSEAQKKMFKQNAVYIVAGGLTGLGFETVKFIAQNGGGCIAILSRSNPS---SEKQEEIKALQNQYE--GSRI
VSLQCNVISHLQVEKAISSITIFPKSPIKGVFHSAVVLHDGRLEALNLSHFEKVLSPKVAGAINLHRATIGQELDYFVCYSSVTSFIGNSTQANYAAANS
FLDVFCHYRR-NCGLSGQSINWGALNL-GLLLNQNIQNILEFKGIDILQIHEIYEYLKKSLILNNPQAVVKLNFGTLSYHVLSR----------------
---IGSLKSRFRTLMSEEFGSKL--EL----------------SE------------QVTP-QNLSPVNSQDYITSLVSYLSSTNALTMNTSLASLGMDS
MLAMTLQNRIFHERRVEIPLVKLLDPHTLSS-VLLLE-------------
>tr|C4NCC1|C4NCC1_9CYAN Polyketide synthase OS=[Oscillatoria] sp. PCC 6506 GN=anaF PE=4 SV=1
DWLYRIGWEVKPLAITKKSKAGSWLIFSDGGEVSNSLAELLNKQGDRCIFVPGSSFSLLEGDRYQINPAERQDFQQLISAIVKKESVCRGIVYLWGSDRN
LE----ISDVTTALDLCTGALYLVQALSEIPHMPRLCL---VTHNGQPVT--QVEQSPLVGLARAIVLEHPELETVCVDLNSRQA-K--E-IEMLVAELL
FPE-EEQVAFRNEE----------------AHSPNINSSGSYLITGGLGALGLQVANYLVEG-ARHLLLVGRQGAAS--PEAQAAVKQLEDK----GASV
KIVKTDISQPDSVATLI---ETDI--PLRGVVHTAGVLDDGMLRNQTHKRFSKVMAPKVKGTWNLHQLTKEMPLDFFVCFSSMTSVLGALGQGNYAAANT
FIDALCHHRQ-ALGLPATSINWGPWASSGMATRLDLQNRWEAIGFGMIPPNQGMYLFGNLLKGQISQGVMPINWSKYPVDS-------------------
--------TFLTEFRK----TTD--KK----------------K-E----------EEKAAEKDRHYPLLLAHVQSQVSKVLGYQKASVTEGFFDLGMSS
LTSVELRNNLQNSLGCRLPATLTFDYPTVKKLVDYLM-------------
>tr|G4XG28|G4XG28_9NOST AnaF OS=Anabaena sp. 37 GN=anaF PE=4 SV=1
DWLYRIGWEVKPRVLAKTSKAGNWLIFSDGGEVSSSLADMLNKQGDRCIFVQGSSFSLLESDRYQINPAEPKDFQNLLSAIVKQDSVCRGIVYLWGLDQK
LE----MSDVTTALNLCSSVLYLVQALSAIPPMPHLCL---ITRNAQAVT--QVEQSPLWGLARVIVLEHPELETVCIDIGSDQV-S--E-IEMLLQEML
FPE-EEQVAFRNGE----------------SQLAKIDSSGSYLITGGFGALGLQVANYLVEG-ARHLLLVGRQGAVS--PEAQAGVKQLEDK----GALV
KIVKTDISQPDSVAMLI---ATDI--PLRGVVHVAGILDDGMLRDQTRQRFLKVMNPKVQGTWNLHKLTKEMPLDFFVCFSSMTSVIGALGQGNYSAANA
FMDALCHHRH-ALGLPAVSINWGPWATSGMATQLDLQSRWEAIGFGMIPPSQGAHLFANLFTAKAPQGAMPINWSKYTVES-------------------
--------AFFTDFRK----TTD--QK----------------K-E----------QQKAAEKEQRQPLLVAHIQSQVSKVLGYQKVSVSEGFFDLGMSS
LTSVELRNNLQNSLGCRLPATLTFDYPTIKKLVDYLM-------------
>tr|K9X6S3|K9X6S3_9NOST Polyketide synthase family protein OS=Cylindrospermum stagnale PCC 7417 GN=Cylst_6228 PE=4 SV=1
DWLYRIAWEVKPSASAQRSKTGSWLIFSDGGEVSSSLADLLNKQGEQCIFVQGSSFSLLNDDRYQINPDEPQDFQKLLSAIVKKESVCRGIVYLWGLERK
LE----MSDVTTALDLSAGMLYLVQALSEIPPMPRLSL---VTCNTQAIT--KLEQSSLWGLARVIVLEHPELETVCIDLSQHQV-N--E-VEMLVEEIL
FPE-EEQVAFRNGE----------------SQSAKIDSSGSYLITGGLGSLGLQVANYLVEG-ARHLMLVGRQGAVS--PEAQAGVRQLEDK----GALV
KIVKTDISQPDSVATLI---ETDI--PLRGVVHVAGVLDDGMLRDQTQKRFSKVMAPKVQGAWNLHQLTKEMPLDFFVCFSSMTSVLGALGQGNYAAANA
FMDALCHHRH-ALGLPAVSINWGPWATSGMATRLDLQSRWDAIGFGMISPSQGMHLFANLLNSKASQGAMPITWSKYPVES-------------------
--------AFLTDFRK----STE--QK----------------K-E----------QEKAAEKDQRQALLVAHVQSQVSKVLGYQKASVSEGFFDLGMSS
LTSVELRNNLQNSLGCRLPATLSFDYPTVKKLVDYLM-------------
>tr|A0A0J6K7Z7|A0A0J6K7Z7_9NEIS Polyketide synthase OS=Chromobacterium sp. LK1 GN=VI26_13855 PE=4 SV=1
REGYAVEWRDAAGGDA-AALPATIAILSGAGDTAAGLAAMLRDEGKEAVVVNDIP-----------------------------FDKAGLIVDCRGLEAR
GDAPA--------PAVYAGALELFATAARRERPCRIAL--------------APASAPLQALSRAVAMETPHLQTLALHAGDARAIR-R-----GLD---
--YRETEVAVKGEAVAAPRFDERALPL---RADLALSADATWLITGGLGELGLRVASWLAALGARALVLTGRRPAD---AAAEAALAALRRD----GVEV
KVWQADVAAEADVDALLAEIATMP--PLRGVCHLAGVVEDCLVGDVTPASLAATLAGKARGAWLLHERTLAYPLEHFVLFSSAAAAFGAPGQSTYAMANA
YLDALAARRR-AQGLPALSIAWGPWQDVGMLARSSAKRRLAQLGIGQIEAECGRATFEIALGADLPHVLLPIDWGRLIEQW---P---------------
---PHVPASRFAGIATA----------------------------Q----------PGAALPAEERRHRLFQLLAEDAALVTGTPLSDPERSLFDYDLDS
LLITDLRVLLEKRFGRAIPTTVIFSNPTIAALADHLA-------------
>tr|Q2SW12|Q2SW12_BURTA Polyketide synthase OS=Burkholderia thailandensis (strain E264 / ATCC 700388 / DSM 13276 / CIP 106301) GN=BTH_I2366 PE=4 SV=1
RDGYAVQWRCVTDGAP-FALPEPIVVVRDAGEVASGLASILRDEAKETLVVDEIP-----------------------------FERAGLIIDCRGIDAR
SAAPA--------PALYEGALALFAAAARRDEPCRIAV--------------APASAPLQALARAAAMETPHLRTLALHAGDAHAIR-R-----GLD---
--CRETEVSVRGTEVTAPRLDERALPR---RAEYAPAGEGTWLITGGLGDLGLQVAGWLAALGVRSLMLVGRRPPG---DAAEETLAALRRD----GVDV
QVRQADLSREADVDALLHEIATMP--PLRGICHLAGVVEDRLVSDVTPASLAATFAGKAQGAWLLHERTRGHALEHFVLFSSAAAAFGAPGQASYAMANA
YLDALAAHRR-SQGLPALSLAWGPWQDVGMLARTAAKRRLAQLGIGQIETECGRATFEIALAADLPHVLLPIDWQRLIDQW---P---------------
---PHVPASRFDGIATA----------------------------R----------PGAALPAAERRHRLFQLLAEDAAAVTGTSLADPERSLFDYDLDS
LLITDLRVRLEKRFGRTISTTVIFSNPTIAALADYLA-------------
>tr|V5IZJ2|V5IZJ2_9PSED Polyketide synthase SpiB OS=Pseudomonas sp. Q71576 GN=spiB PE=4 SV=1
RDGYSIEWRSSSLDRS-FELPQTVVVIRDADGVAEELAAILQAEGKRPLVVSDIS-----------------------------FETTDFVVDCRGSDAR
STAPD--------LSVYEGALDLLGTVARKDLPCCVAI--------------VPSGAPLQALARVAAMETPYLRTLAVRANNAQSIR-R-----GLD---
--FQETEVMVDGDNISAPRFQRFDLPR---RTESSFSGDETWLITGGLGELGLRVASWLSALGVRSLVLTGRHSPD---TNAQETLTVFGHE----GINV
QVIQADLSSEADIEALLHKITTMP--ALRGICHLAGVVEDRLMGDVTPASLKTTFAGKAEGAWLLHERTLHYPLKHFILFSSAAAAFGAPGQAAYAMANA
YLDELAVYRR-SLGLPALSIAWGPWQDIGMAARTAAKRRLSQLGIGQIEEECGRATFENILFADLPHVLLAVDWQRLVGQW---P---------------
---PQVPFSRFDDIVSD----------------------------I----------PGSPLSPDERRHRLFQLIAEDVSSITGTDLTDPERSLFEYDLDS
LLITDLRLKFERRFGRPVAATVIFSNPTVAALADHMA-------------
>tr|A0A0D5L3V3|A0A0D5L3V3_9BURK Short chain dehydrogenase family protein OS=Burkholderia sp. 2002721687 GN=BW21_6308 PE=4 SV=1
RDGYAVEWRDVADGAR-AALPEPIVIVRDAGQVAAGLASLLRDERKDAQVVDEIP-----------------------------FDRAGLIVDCRGVDAR
ADAPD--------AARYEGALALFAAAARRDQPCRIAV--------------APASAPLQALSRAVAMETPHLQTLALHAGDAHAIR-R-----GLD---
--YRETEVAVRGDAVSAPRFEERALPR---RADLALAGDATWLITGGLGELGLRVAGWLVALGARTLVLTGRRPAD---AAAEAVLVALRRD----GVDV
RVRQADVAVETDVDALLAEIATLP--PLRGICHLAGVVEDRLVVDVTPESLAATLAGKAHGAWLLHERTRRHPLEHFVLFSSAAAAFGAPGQSTYAMANA
YLDALAAHRR-AQGLPALSIAWGPWQDVGMLARTSAKRRLAQLGIGQIETECGCATFEIALATALPHVLLPVDWPKLIEQW---P---------------
---PHVPASRFAEIAAA----------------------------Q----------AGAALPADERRARLFQLLAEDAAAVTGTPLSDPERSLFDYDLDS
LLITDLRVRLEKRFGRTISTTVIFSNPTIAALADHLA-------------
>tr|A0A0Q6QR60|A0A0Q6QR60_9ACTN Uncharacterized protein OS=Kitasatospora sp. Root107 GN=ASC99_21940 PE=4 SV=1
GSLFQLVWNPLPLTAL--PDPVDWANLELDNPEVPET-------VLLEI---SAA----------------------------------------AVDLP
A----------GARVAANQVLAVVQEWLADERDSLLAV---ATHGGVT-VVEDLTQTPVWGLVRAAQAEHPG---RFVLVDIDDRAESIA-L--------
--AGETELAIRAGEVLVPRLTALP------AAAPSLDPAGTVLITGGTGGLGALVARHLVTYGVRHLLLTSRRGPAA--PGAAELVAELQAL----GAEV
TVTAADVAERAALEGLLAGIPAAH--PLTGVVHVAGVVHNGVIGSWTPELVDSSLAPKADAAWYLHELTAEMDLGLFVLFSSAGGLVLAQGQAGYAAANV
FLDGLAEHRR-LAGLRATSLAWGAWAVDGMSQYLADLLRMRRQGLPAFSAADGLAMLDSALRVTDAVVPVHVDPVALRAR--------------------
---ADELPA----LLRGLVKAPT--RR----------------PSRAG-------SHQGGVTGAELDRAVLQVVRTHAAEILGHPGADPERGFLDIGFDS
LSALELRNRMVTAAGRNLTPMLVFDYPSASALAAYLR-------------
>tr|K9X335|K9X335_9NOST Polyketide synthase family protein OS=Cylindrospermum stagnale PCC 7417 GN=Cylst_4418 PE=4 SV=1
DWLYEVEWVLQEHNTDKLDTKRNWLILADDQGIGQQLVARLRSQGESCTIIAANEYEQIAEHEFRLNPASPEHFQQLCQAVP----HVHGVVNCWSLNAA
SIQ--TAADLVAAKISCGSTLHLVQAMLENY-PPNLWL---VTQGAQALEKVGLAQSPLWGMGQVIALEHPELNCVLVDLDPNVT-D--A-DRVILSEIS
SQS-EGQVAFRDGKRYVARLVRTQP---D-YHGISFREDSSYLITGGLGDLGLLVARWMVEG-ARHLVLVGRSAVK---PAVRSQLEQLELS----GAKV
VVAQVDVSDYEQVAQLLDSLPSSP--PLQGIIHTAGVLDDRLLKQQNWESFRRVMPPKVQGAWNLHTLTQKLPLEFFVLFSSCVSMLGAVGQANYVAANA
FLDSLAFYRR-SLGLPSTTINWGAWGEVGMAARNQVIERLNRVGMGAIASNQGLQVLEKLLLEQPIRGVIPLNWSQFREKQ-------------------
---W-TASPFFTNFTK----GSE--QS----------------S-K-----------QQAVPVRERKALLVAHVSSHLAQVLGWNPPDRKRSFFEMGMDS
LTSIELRNRLQTSLGSSLPSTLVFDYPTLEELVDYLA-------------
>tr|W4MC24|W4MC24_9DELT Uncharacterized protein (Fragment) OS=Candidatus Entotheonella sp. TSY2 GN=ETSY2_09420 PE=4 SV=1
QWLYQVRWAAQPRLPATTHDPVAWLLFADASGMAEALARQLEQRGDHCYLIPDRDLTQQSPRSWGINPTHVEDFHRLIRELSASELACRGVIYLWGLDLP
SIRD-TPQRLEAEAMGIGGALFLIQALAEARLVPQLWM---VTRQAQHPDDPEAMQAPLWGLGRVVPLEYPRMWGGLIDLPAAEPAWLDD-CQALLAEIL
QPSGEDQIILRRDLRFVPRLVP--------SDGLPSHAEGTYLITGGTGMLGLHIAQWLADPGTCDLVLTSRRGAQ---SMTQVSMSALQAS----GARV
HVMQADMTVTADVQRVIDDIRNLP--PLRGVIHCAGLLDDGVLSQMDWDKFTRVTAPKIRGGWLLHHVTQTMELDFFVLSSSILSLTGSAGQANYTAGNA
FLDALTQHRR-TLGLPSMTINWGPWEDAGLATASGGKAIWQARGTQYIPAEDGMRVFDHLMQHPVDHAVTITDWAIYLDQF-------------------
----ADPPPFYAVLLR----QVG--VR----------------RSPK---------LLRQAPPTEHRDLLLEV---------------------------
--------------------------------------------------
>tr|Q7NJ78|Q7NJ78_GLOVI Gll1954 protein OS=Gloeobacter violaceus (strain PCC 7421) GN=gll1954 PE=4 SV=1
DWFYELAWQPLPLPAPATRPPGRWIVLSGNSALGADLATRLEAQGHSSVRVSEQFAILEPARHYALNGQKPEDFRRLMREIV--NLPLLGVVHLWSLEEA
SGP-----------ALWESALHLVQALV--LAQAPLWL---VTRGTQALGQLAVEHNALWGLGRVIALEHPELWGGLVDLDVEPGRDEAR-L---LAQLQ
APDGEDHVAWRGEERLAARLVQTRQGR--AGAPP-AWESGGYLVTGGLGNLGLQVARWMVEQGARHLALVGRRAPS---PEAEAALAGLRKL----GAQI
CVLQADICDPHQAQAVLEHFDALP--PLRGIVHAAGVLDDGLLVQQNRERFAAVLAPKVQGAWHLHTLTRQIDLDFFVLFSSVAGLLGSPGQGNYAAANA
CLDALAHHRR-ALGLPALSINWGPWAEGGMAAALSYQERIAAQGVSAIPVQRGLKALEWMLRQAVPQGVLPVQWAKF-----VQPF--------------
--LPGRLPSLLRQIAREVQPRQS--AA----------------VPA-----------PSSLGFEPCYALLLTHLRGQLAQVLGLAPSDLEQPVNELGLDS
LMTTELKRRIEGELGVSVPVVLLLQNPSLSQLAWKLA-------------
>tr|A0A0K1S785|A0A0K1S785_9CHRO Malonyl CoA-acyl carrier protein transacylase OS=Microcystis panniformis FACHB-1757 GN=VL20_5149 PE=4 SV=1
KNCYKVEWQLSPLNLKKPSQGERWLIFNDNQGVGKALATTLNDAY-ILVS-SGQTYQKLVSGHYQINPNNVKDFQRLLQDLT---EPITKVVYLWGLDSD
INSQT------SQTRSYASLLYLTQALAQFKTPPKLWV---ITQQAQPVNDVKIAQTSLWGMGQVIALEYPNLWGGLIDLEEKQP-SSQA-I---IAEIT
ENLGEDRIAFRDHQRYVARLVPNKAIK---NINF-KKTEASYLITGGLGSLGLSLADWLIEKGANHLILTSRRALA---DHSQVKIKALEDK----GATI
QVIAADVSDYQQTRQLFHQIENCP--PLQGIIHAAGVLSDRTIDKMDFHCFESVFNPKAAGAWNLHQLSQDLSLDFFVCFSSISALIGSRGQIHYAAANH
FLDGLMHYRR-ESGLTGLSINWGPWAKGGMATQ--YEEGLKRLGINPLQPNLALDTLDALIHGNVT-MVAEIDWSKF-----KTIV--------------
--AAKGRVAFLEALFKQDQDNFV--QT----------------V---------------KNPPHRRVTLLTTRLQQEVAQVLGIHGLDTDQGFFEMGMDS
LMSVELKHRLEGLFSVSLPSTFAFEYPTIGDVVQYFV-------------
>tr|A1YBR0|A1YBR0_SORCE AmbH OS=Sorangium cellulosum GN=ambH PE=4 SV=1
EHHYETEWRLAERERPAEPRRGGWLILDDQAERAAALQDYLEARGQTCVRVAADTYARRGARDYQIDPREPEHFARLLGEQEDASSDRCGVVHLWSAHSS
PAPTLE--SIQAQALGSISALHLVQALARAGWPPRLWL---VTQEVQAIKNTSVAQAPVWGFGATVALEMPELQCTLLDLDATPNID-A--L---GQELL
SASDEDRIALRGAERHVARLVPHVPEQ--APEPLSFKADATYLLTGGLGGIGLVVLEWMAARGARHFALLGRSGPS---ASAQPVLDRMRED----GAQV
RTFSVDVADRERLRTVLAQITSMP--PLAGIIHAAGVGDQKMIPDLDGPSLQAIGRPKVDGSWNLHELTSELPLDFFVLFSSVSSLFGSHGQSSYAAGNA
FLDALSHHRR-ALGLPALSLNWTAWTDVGMATPIITSRYLATQGMGALSSREGVAALEQLFRASSAQGVVPLSIPSLPRKPFYSVV--------------
--APPTAPTPTAQT---------------------------------------------ARPPGERQEAIEGTLRELFARALRMPPKKLTEALQNLGVDS
LIALELRRRIDEELGVKLQAAEIARVANVRELAQLVT-------------
>tr|A7IE16|A7IE16_XANP2 Beta-ketoacyl synthase OS=Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2) GN=Xaut_1008 PE=4 SV=1
DSLYHLEWHERPRASHSADAAGLWLLSGVPGAVADSLAEALRQRGVEVRLVGGDLAADIAA-----------------------AAALRGMVLLEDGAGG
TDVQE---A--VFEAVAGRALPAVKALA--EGGARLFI---VTHGAIACDGDDLVAAPLWGFGRVVGLEHAEIWGAQIDLDPADPAGSAA-A---ADEML
DLGADREIALRAGRRRVGRLARLPKPD---AGPVLLRPDASYLVTGGLTGLGLETARFLVARGARRLILIGRTALP---PRAVAAVRGLEQL----GASV
RVEAFDVADEARLAAFLAAYEAHP--PIRGVVHAAGVIQDALLLRMTGEDIAAVMRPKVAGALALHRQTADLPLDHFVLFSSASSVLGQVGQAGYGAANA
FEDALAAHRR-AAGLPATAINWGPWADIGLFARL-LAERAGLSGVEPIAPEQGMAALDHLMARGETQLVLNADWAQVPASARLELL--------------
--QAASAPD---------TPST------------------------------------SLMAPAERKAELRARLGAIVAAVLRFDAKDHRRALTTLGMDS
IMAVEIRNRVRRQFDLTPSIVDLFTGSVARLADW-LD-------------
>tr|A0A074LK99|A0A074LK99_9BACL Uncharacterized protein OS=Tumebacillus flagellatus GN=EL26_14360 PE=4 SV=1
SWLYEVQWEETPLPATPAEQQGLWLMLCDTAGVGDALADLWQQQGRTCIRLSGDSFQELGPLRFAVDPAREEDIRQALQIAYTLSEPLAGALHLWSLDIP
IESMAQKERLLASRLALQSSVALVKTLSSDPLRTKVHF---VTRGAQAVDS-HVNQAPLWGLARSLPMEHPHLWGGLLDLDPNASSA-Q------SAEWL
NLTEEDQTAIRNGRLYNARLRTPDKAK---GEPTPISEDGTYLISGGLGGLGLETAKWLAKQGARHLLLLGRTPMA---PRSAATLLDLEQQ----GVQV
ETAAVDVSDAEQIRACLHQRRGVP--AVRGVFHLAGNAEGSLLTDLSAQTLSNILSPKLAGAWALHTALEGAELDCFVLFSSASSLMPSPMISAYGAANA
SLDAFAHYRR-SLGLPALSINWGPFAQVGMAMQNTQNERQSFGALQLIQPEEALDGMRRLLAGSGSQAVFPINREMW-----YQLY--------------
--ERNRTFPLLRALST-----------------------------A-----------PV--ASALKVDHVENYVSQQVANVLRLSVKDVQESMLNLGMDS
LMLTELKNRIETDLNVSLPLVKLLQGPSVHQLSEMIR-------------
>tr|A0A0H4WWB1|A0A0H4WWB1_9DELT Malonyl CoA-acyl carrier protein transacylase OS=Myxococcus sp. (contaminant ex DSM 436) GN=A176_002820 PE=4 SV=1
DWTYAHAFEAT-AEELPAKSTGAWLVFADQGGLGAELAKALEQSGAQDVVRRGERFARDSSGHFQIRRGEAADVRGVVDAVG--RVRIQNVAYLFGLDAS
PGGESE---------DVQALLDVVLAL---APGASIRI---VTRDAQRALPDAVSAASLIGFARVVPAEMPHLKTRSIDLPRDASASQEL-VERLARELL
A-EKEEEVALRDTRRLARRLNARPLPEWEAVDERLFDANATYLVTGGFGGFGLALARWMVAEGARHLVLTGRKGAST--PEARQLVQDLEAA----GARV
TPAAADVSSMDDMRALFARIADHP--PLKGVLHTAAVLDDAPLPDLNLQRIQRVMTPKAGGAWILHELTQERPLDLFVLFSSVAALIGNPRQGNYVAANS
YLDALAEHRA-ARGLAAVSIHWGVLGEFGMAQDEAVRTYLESLGLNPMAPATVLTALKRVLRLRTAQGLFDVQWAKLGRAA---P---------------
---HLGKSARTEHLLG----------------------------SAQG-------GGQNGLSTDDRRPELEKFLVERLATILQIPTREPQKPLSLLGVDS
LLSMQVQRTIREALGIEIPALELLRAGSLVEVAGNLS-------------
>tr|Q1D518|Q1D518_MYXXD Polyketide synthase type I OS=Myxococcus xanthus (strain DK 1622) GN=MXAN_4077 PE=4 SV=1
DWTYTHAFEAT-AEELPAKSQGTWLVFADQGGIGAELTRELQRTGIQDLVLRGETFVRESNHRFQIRPGNAEDVRSLVEAVG--RVRIQHVAYLAGLDAR
PGVESN---------DVQALLDVVLAL---APGASLRI---VTRDAQRAAPDALSATPLIGFARVVPAEFPHLRTRSIDLPKSASASQEL-IERLARELL
A-EQEEEVALRDTRRFVRRLSAKPLPEWEAADEPLFDANATYLVTGGFGGFGLALARWMVAEGARNLVLTGRKGAST--PEAKQLVQDLEAA----GARV
TAAAADVSSMDDMRALFARIATHP--PLKGVLHTAAVLDDAPMPDLNLERIQRVMSPKAGGAWILHELTQDRPLDLFVLFSSVAALIGNPRQGNYVAANS
FLDALAEHRA-ARGLAAISIHWGVLGEFGMAQDEAVRTYLESLGLNPMAPATVLTALKRVLRLRTPQGLFDVQWSKLGRAA---P---------------
---HLGKSARTSHLLG----------------------------SAQG-------GAQSGLAPEARQPELEKFLVERLATILQIPMREPQKPLSLLGVDS
LLSMQVQRTIREALGIEIPALELLRAGSLVEVATNLS-------------
>tr|A0A085WP69|A0A085WP69_9DELT Malonyl CoA-acyl carrier protein transacylase OS=Hyalangium minutum GN=DB31_6457 PE=4 SV=1
DWTYEHVFEEARPEEAGAKSSGGWIVFADRGGLGAELVRALERSGVQDIVQRGEAFARESATRFQVRPGEAEDAGRLVDALG--LARFRNIAYLFGLDAS
QVADAG---------DVLEFLRVVMAV---APGASLRI---ITRDAQRAIPDSLAAAPLIGFSRVVAAEFPHLRTRTVDLPQGASAAQEL-IERLARELL
A-EQEDEVALRDTRKFVRRLKQRPLPEWEAADERLFDANATYLVTGGFGGFGLALARWMVTEGARHLVLTGRKGAST--PEARQLVQDLEAA----GVRV
TGVAADVSNRDDMRALFARLATHP--PLKGVLHTAAVLDDAPLPELNLERLQRVMAPKAGGAWILHELTQDRPLDFFVLFSSVAALIGNPRQGNYVAANT
FLDALAEHRA-ARGLAATSIHWGVLGEIGMAQEEAVRAYLESLGLHAMPPASVLAALKRVLRIRTPQGIFDVSWPKLGRAA---P---------------
---NLGRIARTAHLIG----------------------------DSQD-------GAQSELSPEARQPEIERFLAERLSLILQIPVRDPQKPLSALGVDS
LLSMQIQGAIREALGVEIPVLELLRGASLVQVASTVS-------------
>tr|E3FG11|E3FG11_STIAD Polyketide synthase type I OS=Stigmatella aurantiaca (strain DW4/3-1) GN=STAUR_1142 PE=4 SV=1
DWTYEHIFEEAKPEEGGAKSSGGWIVFADRGGIGAELARALERSGVQDLVQRGEAFVRESDTRFQIRPGDAGDAGRLVEALG--LARFRNIAYLFGLDAS
QVADAA---------DVSEFLRVVMAL---APGAAIRI---VTRDAQRAVPDSLAAAPLIGFSRVVAAELPHLRTRTIDLPRAASAAQEM-IERLARELL
T-EQEDEVALRDTGRFVRRLKSKPLPEWEAADERLFSADAAYLITGGFGGFGLSLARWMASEGARHLVLTGRKGAVT--PEAKQLIQDLEAA----GVRV
TGAAADVSNKDDMRALFARIATHP--PLKGVLHTAAVLDDAPLADLNLERIQRVMAPKAGGAWILHELTKDRPLDFFVLFSSVAALIGNPRQGNYVAANS
FLDALAEHRA-ASGLAAASVHWGVFGESGMAQGEAVRAYLESLGLHAMPPASVLGALKQVLRIRAPQGIFDVSWPKLGRAA---P---------------
---ALGRTLRTAHLIG----------------------------DTQG-------GAQSGLTLEARQPEIERFLTERLALILQIPVRDPQKPLSMLGVDS
LLSMQVQGTIREALGIEIPALELLRGGSLVQVASTLS-------------
>tr|C1F4N8|C1F4N8_ACIC5 Monooxygenase, luciferase family/oxidoreductase, short chain dehydrogenase/reductase family/phosphopantetheine attachment site 
PLLYRRSWIEAAAPDSPADRTGTWLVLAHHSDLADGLSSFLQGVGTCKIIQPEEGQL----------------------HLTGPSFAWRGVICLLP--DI
-----NT-------------ALTAQALTG--TNIPLWLVTQGAMPLPDSAPCSMKDAAVWGVGRALAVEQPANLGGLIDLDPAGSS-----GYDLGQVLR
SNGGEDMIALRGGTRYVARITRDDIPAKP-AKRLRFRKDATYLVTGGAGGLGQQVIQWLQSKGAENIAVLSRRMEASLRD-----------------G-I
TTFRCDVTQHNEVAAVLDQIR-QSMPPLRGVFHLAGMLDDARLADLNMDRLQLAGAAKSGGAWNLHELLADTDLDHFVLFSSMASLVTMPGQGSYAAANA
SLDALAHTRR-AVGKTALSINWGPWSGAGHAYGKRAHEALAALGIAPLAPELALAALNFLMERDVTQAGAQVDWQRL---------------------F-
---------KNDPQAKSPLLSNFLPARQ---Q-----KA-----ATET---ALVQELGTCAP-GTRATLLIDHLTVILVDILRLPLVDSTQSFFHLGLDS
ILALEFTARISAGIGRPLPATTFFTHSTLDALAAHILNS-----------
>tr|D6TD66|D6TD66_9CHLR KR domain protein OS=Ktedonobacter racemifer DSM 44963 GN=Krac_11725 PE=4 SV=1
SWLYELRWEKQDFATNPEERSGTWLIFADRQGVGQRLAQHLQARGQCALVQAGSHYGALGLGRYQVQPQLNDVQRVISRVQETFATPLRGVVHLWSLSEQ
-----TTAQTLEHDSALGVMQSLAQNTSA--QLPRLWLVTRDAQAVTDNAALAVAQSPLWGLGRTCAMEHPEIWGALIDLSSQEGIEE--GAQQLYASLL
DTSREDQVAFRQGERYVARMVRSHDFVA---RDLHIRAQGSYLVTGGLWGLGFEVARWLAQKGARSLILAGRTQVPPRSEWDRIPATDRGIRELEAEGVV
HCVQLDVTDEAQLRAFLADHMRQGHPPIKGILHAASVWQVKPLINLDASALDAVFRPKVIGSWLLHTLFQESRLDFFVSFSSGASLFGSAAQGNYAAAGA
FMDSLAHYQR-AQGLPAISIDWGAVSEIGFGEGQRVHEYWESHGIQRISPRDVLAALELLIPQQAAQVGLKLDWQLL---------------------R-
---------EFYPQIALPLVSYLVEDTSEQRT-----PT------STG---SGIDAILRATD-SERLSLLEQYLSEQVAAVLRVPRLDSDQPLTTLGLDS
LMAIELKNRLEQALGVRVPIVTFLQGPSIAQFASQLLEQ-----------
>tr|A0A0C2LZ49|A0A0C2LZ49_9CYAN Uncharacterized protein OS=Scytonema tolypothrichoides VB-61278 GN=SD80_31605 PE=4 SV=1
DWFYEVQWEPTSPLNNQPEQLGSWLIFADSSGVAQKLAAVLTARGTCFIISP-SKDQVSEQGQFWIDPRPEQMHQFIENVLEPNQPLCKGAIHLWSLSDE
-----MTSSSLQTSSVLSLLQALSNVKQS--VLPRLWLVTKGAQSTGESSLPAIAQTALWGFGKTCATEHSDLWGGMVDLDPQATKDE--AASQLLSVIS
TQDVEDQLVFRHGQPYVPRLVQKRESVEN-ALPFSWRNNYSYLLTGGLGGIGLQVAQWMVEQGARHLILLGRTPLPPRSTWTEVKEDTSAILNLEAQGAV
YLASVDVADETQMSEMLETLKEQGCPPVRGVVHMAGI--GKLLQELDAERANQVLRPKVMGGWLLHRLFEKVDLDFFILFSSATHQLGSRGVGDYSAGNA
FLDALADYRK-AQGLPAVSIEWGPWAEVGMARNDR----LARFGIGSITPEQGLEAMSRALRQNSPSVWIPINWSQL---------------------L-
---------QMDQIAKSPFLSKLSRQVFSQQQ-----LK-----ASES---EILQKLKQHQP-NERFSVLTAYIQGEVAKVLMLEKPDPQQGFFDMGMDS
LMAVELKNRLEASFGASLPVTLTFEYPTIKDVVGYLVRE-----------
>tr|A0A0J5X7D7|A0A0J5X7D7_BURCE Short-chain dehydrogenase OS=Burkholderia cepacia GN=VL15_08540 PE=4 SV=1
ALLYQRVWRPSSVEAAGASAHGEWLILADRGGVGAQLSALLESAGTCALHFADA-SA----------------------ALPALDRPLKGVIHLWSLADV
-----AARRRASA-SVLQLVRALARAPSA--RQARLWLVTSGAMNVLDGESTAVAQAPLWGLGRAIAVEHAPLWGGLIDLDPAQPS-----ATDIVQAVL
AGGREDMIAFRGGQRHVARIARDNEF-VS-HRPVRFHPDAAYLVTGGLGGLGLRLAAWLAGNGAGKVVLLGRSKPSAAAEKIL-----------QTLD-A
RFIHADLSRRGDVADAIDEIA-RSMPPLKGVFHLAGVLDDALLARQDDDFFHRAGSGKADGAWYLHELTANLPLDHFVLFSSMAALITMPGQSNYAAANS
FLDALAQHRR-AQGKPALSVNWGPWAEIGHAYGRRAHEQLGALGVGTLSPELAIATLERLMASGVAQSGARIDWPTL---------------------F-
---------RVDAPAGSALFSELAQPAA---Q-----PA-----QQET---ALLRQLHPCAP-RERLELIAGTLAKMLAETLRLPDIAPEQSLLDLGLDS
LIALELTDRLTKVFGRPFRATLFFSYPNLQALARYVLGE-----------
>tr|A0A0D5EGX4|A0A0D5EGX4_9BURK Natural product biosynthesis luciferase-like monooxygenase domain protein OS=Burkholderia ubonensis MSMB22 GN=BW23_5767 PE=4 SV
ALLYQRVWRPSSGDAAGRSAHGEWLILADRGGVGAQVAALLESAGTCALCFADA-TP----------------------HLPAPDRPLKGVIHLWSLSDI
-----AARRHAST-SVLQLVRALARAPSA--GQARLWLVTSGAMNVLEGEATAVAQAPLWGLGRAIAVEHAALWGGLVDLDPAQPS-----AAHVVQAVR
AGGREDMIAYRRDQRYVARIARDNEF-VS-HRPIRFHGDATYLVTGGLGGLGLRLASWLAANGAGKIALLGRGEPSPAAEKIL-----------RTLD-A
RVIRADLSRREDVAAAIGEIA-RSMPPLKGVFHLAGTLDDALLTRQDDDAFHRAGSGKADGAWYLHELTADLPLDHFVLFSSMAALLTMPGQGNYAAANG
FLDALAHHRR-AQGKPGLSVNWGPWAEIGHAYGRRAHEQLAGLGVGTLSPELAIAALERLMASGVVQSGARIDWPTL---------------------F-
---------RVDAPAGSALFSELAQPAA---Q-----PA-----QQET---ELLRQLRSCAP-RERIELVTGTLAQMLAKTLRLSDIAPEQSLFDLGLNS
LIALELTDSLTKVFGKPFRATLLFSYPNLQTLAQYVLNE-----------
>tr|A0A087NRX9|A0A087NRX9_BURPY Short-chain dehydrogenase OS=Burkholderia pyrrocinia GN=JM78_19280 PE=4 SV=1
ALLYRRVWRPSSVDAAGGSAQGEWLILADRGGVGAQLSGLLESAGTCTLRFADA-TP----------------------EPSALDRPLKGIVHLWSLADI
-----AARRRASA-SVLQLVRTLARAPAA--RQARLWLVTSGAMNVLDGESTAVAQAPLWGLGRAIAVEHAAMWGGLVDLDPAQPS-----AAHIVQAVQ
AGGREDMIAFRRGQRYVARIARDDEF-VS-HRPIRFHHDATYLVTGGLGGLGLRLASWLAANGAGKVVLLGRGAPSPAAEKIL-----------RTLD-A
RFVRADLSRREDVAQALGEIA-DSMPPLKGVFHLAGALDDALLTRQDDDFFHRAGSGKADGAWYLHELTADLPLDHFVLFSSMAALITMPGQGNYAAANS
FLDALAQHRR-AQGKPGLSVNWGPWADIGHAYGRRAHEQLAALGVGTLPPELAIATLERLMASGVAQSGARIDWPTL---------------------F-
---------RVDAPAGSALFSELAQPAA---Q-----PA-----QQET---ALLRQLHACAP-RERIELITDTLAKMLAETLRLSDIAPEQSLLDLGLDS
LIALELTDRLTKVFGRPFRATLFFSYPNLQTLAQYVLNE-----------
>tr|I2DZ62|I2DZ62_9BURK Uncharacterized protein OS=Burkholderia sp. KJ006 GN=MYA_5597 PE=4 SV=1
GLLYQRVWRPSSADATGASSAGEWLIFADRGGVGAQLAGLLESAGTCTLQFDDT-TP----------------------ALPALDRPLKGVIHLWSLADI
-----AARRRASA-SVLQLVRALAGAAAG--PQPRLWLVTSGAMNVLDGEATAVAQAPLWGLGRAIAVEHATLWGGLVDLDPEQPS-----AADVVQAIR
AAGREDMIAFRRGQRHVARIARDNEF-VS-HRPVRFHRDATYLVTGGLGGLGLRLASWLADNGAGQVVLLGRSAPSAEAEQML-----------RTLG-A
RFIRADLADRDDVVQALAEIA-HAMPPLKGVFHLAGALDDALLTRQDDDFFHRAGSGKADGAWYLHELTADLPLDHFVLFSSMAALLTMPGQGNYAAANS
FLDALAQHRR-AHGKPALSVNWGPWADIGHAYGRRAHEQLAALGVGTLSPDLAIATLERLMAAGVAQSGAHIDWPTL---------------------F-
---------RVDAPAGSALFSELAQPAA---Q-----PA-----QQET---PLVRELQACAP-RERLALVTDTLAKMLAETLRLADIAPEQSLLDLGLDS
LVALELTDRLAKTFGKPLRATLFFSYPNLQTLARFILDE-----------
>tr|A0A066Y6T0|A0A066Y6T0_9ACTN Uncharacterized protein OS=Streptomyces olindensis GN=DF19_13900 PE=4 SV=1
DLCYRTDWTAVS-AAPADTESGRWLVLADRAGTGEALAMALREAGSVEVVQADAASDAAHIR------------QALYGAL-ADGPL-KGVVLARPLLPD
-----ATTDQVRAAAALALVRACLVDVPT--RCGRLWLLTRGAQPVGTVTAAGVLQAPVWGLGRVLAAEHPELWGGLIDLDARTAPDE-AASAALLSAVL
TGAVDDQLAVRDGSLLAARLVRAEMAAPA-PAAPDIDPDGTYLLTGGLGDLGLAMAGWLAERGARHLVLVGRRGVSDDT-QREAVD------GLTGRGVV
HVAVADVARADDVAALRAELEREGMPPVVGVAHLAGIARGAMLAGLDVEQLREVAEPKVAGAWNLHRVFGDAS--LFLLVSALPAVFGGVGAANYAAANA
FLDALAHHRR-GLDTDAVALGYGPWNGIGLAGGL---EQLSRLGVGSMAPAEALDVFGRVLARRPAQVTARLDWPEV---------------------F-
---------TAVPSAATGQFAAFLEEFGGTSA-------------------HLLERCAQAAP-QEQRTIVGDYLTERLAAVLQTGDIDPQVPVVEMGLDS
LMALELRVRVKADLGVVVPMVRLLEGPSVEQLTDHVLGL-----------
>tr|F8CI87|F8CI87_MYXFH Short-chain dehydrogenase/reductase SDR OS=Myxococcus fulvus (strain ATCC BAA-855 / HW-1) GN=LILAB_09175 PE=4 SV=1
ALTYALDWRPRTAPAPAAAGPGTWWVLMDGRGVGKALATRLEARGTVVRITAGATFQSLGPRDYQVAPDAAQLRRLVEALLVAGGPVPRGLVHLWSLPAQ
-----TTVETLEAETVLGLVQALV-SGAV--RPPRLWLVTRGCQPPAAG---ALASATLWGLGRVVSAEHPEVWGGLVDLEPDAPGDA--SAAALCGVLL
APGGEDQFVLRGEAQAVARLARRRLPSGG--PATRLRADAGYLLTGGLGDLGLGMARWMVERGARHLVLMGRSPLPPREDWAYVAPGSRAIRELEALGAV
YPAAVDVADRDAVATFLRGYHAEGGPALRGVLHSAGVIQPATLMNLGADALHAVLRPKVAGAWVLHALLEDTPLDFFVLISAVPGLVGGSGASNYAAANT
FLDALAHHRR-ARGLPALSVDYGPWSEVGLAGGL---PMLERQGIGSMSPPQGLAALDRALTQPDAQLAASLDWPRF---------------------F-
---------RAFAHATTPLLAEQVKEAGEGPA-----RS-----PEAG---ALQAALSEAQP-GARSELVREYLRTQVARVLARSRLDVNASLMSLGLDS
LMSIDLRNRIESDLGVVIPMVNLLRGPSIAQLVDDVLPA-----------
>tr|B4VZM3|B4VZM3_9CYAN KR domain family OS=Coleofasciculus chthonoplastes PCC 7420 GN=MC7420_2488 PE=4 SV=1
DWFYELQWQPQPLLSSPIREPGSWLIFADLTGIGQALAQRLEAQGICRLVYAAEEDAVAQEGQILLNPEPEAMQALIEQM--ETLPPCRGVVHLWSLPEA
-----TTLSSLDKDSTLHLIQALQRTNRS--QLPQIWLVTQGAQRIGEAVPPAIAQAPLWGVGRSLAMEIPQMWGGLIDLDHDVSPVN--AANALFEQLW
YPDQESQIALRCEQRYVPRLVPSPKQSIP-KQPLSLQSDGTYLITGGLGHLGLNTARWLVENGARHIVLMGRGEASS---TAQQAI-----RQLEALGVV
LVVKADVCNQADVVEVLEKIN-AYSPPLRGIFHAAGV--FHRFSDMTPDLIQSILAAKVIGTWNLHQITLGLKLDFFVCISSITSLWGAEGLAYYAAANQ
FLDLIAHYRH-HLHLPALTVNVGALAGGGMHQGVALREIVTQIGLKYYEPQLFLKTLESSLVRGVAQPIVDIDWAIF---------------------K-
---------QLYEARRRTLLKEIEVKSPQPVQ-----PL-----GKLG---QVLQQLKETSS-SDRDEFLITYLQENVALVLKLKQPSSEQNLTEIGMDS
LTAMEFKNSIHQELGIDIPIVQFIGGTTIAALAAEINKQ-----------
>tr|A0A0C1TWP4|A0A0C1TWP4_9CYAN Uncharacterized protein OS=Hassallia byssoidea VB512170 GN=PI95_57895 PE=4 SV=1
DWFYELQWEATSLPNNQPEQQGSWLIFADSSGVGQKLAALLTARGTCFIISP-SEYHVSEQGQFWIDPCPEQMHQLIENVLGPNQPQCKGAIHLWSLSHE
-----MTSASLETSSVLSLVQSLSNVKQS--VLPRLWLVTTGAQSIGS-SLPAVAQTPLWGLGKTCATEHSDIWGGMVDLDPQATKDE--AASQLLNVIC
GQDVEDQLVFRQGQPYVARLVQ-RESVEN-ALTFSWRKDCSYLLTGGLGGIGLQVAQWMVEQGARHLILLGRTPLPPRSTWSEVEEGSSAILNLEAQGAV
YLASADVADETQMSEMLQTLKERGCPPVRGVVHMAGI--GKLLLELDATRMNQVLRPKVMGGWLLHRLFEKVDLDFFILFSSATHQLGSRGVGDYSAANA
FLDGLADYRT-AQGLPAVSIEWGPWAEVGMARNDR----LARFGIGSITPEQGLQAMSRALCQNSASVWIPINWSQL---------------------L-
---------QMDRFAKSPFLSKLSSQVLSQRE-----LN-----AIES---EILQKLKQHSA-SDRLSVLIAYIQGEVAKVLKLEKPDSQQGFFDMGMDS
LMAVELKNRLEASFGVSLPVTLTFEFPTIKDVAGYLAKK-----------
>tr|E6U7B9|E6U7B9_ETHHY 6-deoxyerythronolide-B synthase OS=Ethanoligenens harbinense (strain DSM 18485 / JCM 12961 / CGMCC 1.5033 / YUAN-3) GN=Ethha_02
------AWRERALARQETAQKQPVLFCSDGSAQAEAIRTALVERGHAISTRFCKRFEKRANSEYSLGSSA-EDSTAFLREMQE--GRWKKIVFFRASEKS
RMARETLDAKETVENGLYRMLSLVKAIEKQSQKAEFIVVTDRAEEVTGEETLHPENAMYSSLGKTVNQECCRVKCRVIDLDEH--T---S-PAAAVDEIL
FG-KDQAVALRNDRRLIQRLEPVHLHKTEN-GNDPFREGGVYVITGGSGALAAHVAKWIAARRGTHLILIGRSPIDAAGGSQAATLETME-AIRALGSSA
EYIQADVADERAAAEAFDRIRRTYG-RLNGVIHMAGITGNRMIVNMERSDFETVLAPKVFGTWNIDRLTQGDDLDFFLLFSSGVSFIGETGLAAYAAANQ
FLNSFAQCRR-RT-RSVQAFDWVVWENQRMMDGYSRNVDGWFEQIRPNDALACMRE----LMPRR--------ESGLLIGRLNRKNRY---EKSMFSHLP
-------F-EVSEEVQRMVRITERAAAPDH--T----ETGRRA----------------ASPHPADPRTIEGTLTGIFREVLGYQEIDIHDNFFDLGGNS
ILLKKLHQKVDEAFPGQVEVADFFAYTTVSKMAAHLAQT-----------
>tr|B8NYX0|B8NYX0_ASPFN Polyketide synthase, putative OS=Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / NRRL 3357 / JCM 12722 / SRRC 167) GN=AFL
------GV----LNGS---DQVQVLTYLMQIGLSEVLRS----LGS---------------CGAVIGHSV-GEIAASVACITP--AEGTLIVTRRFMGAG
GMALVCAPLQITIEISTQNVNNLVVAINS---SPSSCVVSGPKEEIEAFALLNN----------------KGIK--TIHVDTD--I---AFHHPMLGELM
EPLAEALVGYVS------------PSQSK---------VAIYSTSAPRSTMDRGIRYWLDNM------------VNTSAASPLAIIKKIL-SMESRGATI
QAIAIDISSHDAASQLSSRIDLCFP-PIRGVVHAAGVLHNEHVLSVTPDSFERVLAPKIAGSLTLNMLFPPKTVDFMVLFSSCGQFFGFPGQASYASGNA
FLDALATYRR-SQGDNTIAMQWTSWREIGMAAGSEFVAELATKGITDIEFQAWMHV----SKYDV--------DHAV----VLRSRAL-------EKHEP
-------L-PSPLLVDIAIHKISSITPPPT--P----PLSSDL----------------LPNPADRFDSLSRQVRECVANVLQTDEVASQEPLSNMGMDS
VMTVHLRGRLQKSLGVLVPPNLTWSHPSIDHIVKWLMEK-----------
>tr|W4BCK0|W4BCK0_9BACL Beta-ketoacyl synthase family protein,phosphopantetheine-containing protein OS=Paenibacillus sp. FSL R5-192 GN=C161_02760 PE=4 
------GWVCEPERNSDKLSEGHVVIFMDEKREDRSLRKALQKQG-LIEVFDGPSFLQVSSGEYVISHQR-ESMEQLWAHLGE--LMITQIIY---I---
-----------QQQQSFHPFFYLLQEMIRTSEPVDVVLLTNPIHSITGTEEVFPQAALMFGLGLAGRKEDSRLQCRSIQVDAE--T---S-LQDILAELD
HESDDYGVAYRAGTRYIQQFEAMDPSQYPK-RDYKIRNDGLYLITGGLGGIGLEIGLQLAERPGITLALVNRTALPWDS-DALVKIRSVQ-QMEAAGATV
LSYQADISDEASMRVILSELRQQYG-RIAGVIHGAGVAVGGDHPDRTIEEAECVLRPKVQGTQVVDQLTREDNPDFFVMFSSIATLFSGPGQADYVAANA
YQDAYAAYRN-RELDGTMTVNWSTWKETGAAAATGYG-DTLFKAMTNKEALAWLDQ----VEGRQ--------IERVLIGQMSTDRGM----LKMIRNYP
-------F-RLSPELENWIDSRLQRSSPKA--P----VTPRQD----------------AVADDGEYTPWEKQVADVCQAVLGFNEIHIHDSFFELGADS
ILVKQMYAQLDRQYPGVLVVADLFEHPSVHRLGGYLADK-----------
>tr|W4DBL4|W4DBL4_9BACL Beta-ketoacyl synthase family protein,phosphopantetheine-containing protein OS=Paenibacillus sp. FSL R7-277 GN=C173_20391 PE=4 
------SWSVNESEDPRPFEASIVLIFKDRSGYAGELASGLRNYGEVVEVEYGHGFQRAGDNRYIIGYSE-NDIFRLLDEIQP--ASSLRIVHMATIGNS
-----IAGEDEQPELGVYSLFHISKAIEALINKAELYLITQNANEITSFKEMNPGNAAFLGLGKAVNLENHRLQVSAIDFDQH--V---F-INKIIDEMG
ARHTALDVAYREGKRYTGSLESVSINMVDDHHPVVYKENGVYVITGGTGSLGLLFAKHLASQAKVNLALINRSELPWTASKALRKIEDLL-QIESTGASV
TVYAGDVTIESDMSAILNDLRRKFG-TINGIIHGAGVAGRELVLDESRDSLERVMEPKVKGAVILDRLTEKDQLDFFVLFSSVVALTGGIGVGGYTAANA
YLDGFASWRS-RRGKRTLSINWPTWRHSVEHTLTTFDSKHLFKLLKVDDALRGFQA----AVSKS--------VSRLIIGELNYSGNL----MYLERFLP
-------I-EFSPEIKRKLARLEKRTKHRT--P----AVDKQA----------------AQ-GGNKCSTTEQRLSEIWSRVLGVEEISIYDHFDDLGGDS
IMVAQLFKELELEYPGRLEIVDVFSYSSISSMAQFLDRN-----------
>tr|A0A0B4XCA8|A0A0B4XCA8_9RHIZ Polyketide synthase protein OS=Rhizobium gallicum bv. gallicum R602 GN=RGR602_PC00360 PE=4 SV=1
-------------------------------------------------------------------------IQALLRHTTGKDAPECRLIYVAFASSQ
EDGETAPQAGPDATQDALRFVRDASAF--DGSDLKVQILTRNAVSIDQDLPVVPAQAAIWSVATVFGQEHRDIWHSVIDFDQSSTDLV---VA-R-LLRG
DLADQT--ALRRRSSFVARLEDVELAESR---SLAFRDDATYLVTGGLGGVGRSLVRWLADCGAKNILLIGRS-LEDETK------RSELKALRERIPNL
RFERADVASRADMARIFSDIEVS-GFPLRGVFHAAGVNENGMIADVAHDALDRALRPKLHGTLVLDELTRSCEMDFFICFSSLSSMLGFKGQAAYVAANA
AMEAIVTKRV-CEGFPALAICWGPWAGDGMSASLGQKARLAAMGIREFSPDEGVEKLSRLFGLSGVYGAFPIVWQSYL----------------------
---------DQFNQRI-----------PPLFSSVTSHKQTSAVRTAKRPFKDE---AAA-LPIEERTDFVVSSISAIVAKTLGPKSVTIDKPINRLGFDS
LTTLELRDALK-ALGVVLPLGPLFSGASIADISKIILDQ-----------
>tr|Q982I5|Q982I5_RHILO Polyketide synthase OS=Rhizobium loti (strain MAFF303099) GN=mlr9053 PE=4 SV=1
-------------------------------------------------------------------------TGGVLDAH---------VAGIIVTPES
AEGASSGQIGEAAHSTLMQFVQTVQAATKNGNKAKIWVVGQSGRAVPAARPASLVSASLHGMAMVLASEHPDLWGGDIDLGAEPSDAE---IA-VAILVG
GSGSETAYAVRGEERYVLRLSESGDV-GT---DCPVDPQKIYLVTGGLGALGSLMVEWLINRGARRLVLLNRD-VADGAK------QERLEALRRLGAEI
AAHAVDIADQVGVERILGDLSEA-GHQLGGIIHTAGVVQDATLGSIKASELEHALRAKLQGTLILDKASRRFSPDFFVCFSSVSALLGMKGQAAYVAANA
AMNRIVEGRN-AEGLPGVSIEWGPWAETGMASGLDLRKRLTDFGLLAIRNREALERLESLCASTGTLTAAPILWRRFC----------------------
---------KKQYGQT-----------PAWLTPLSNVQKNPQADEATDPLARL---FGP-VAPSDRSQAIESFLRGEVARVLGPDCLPMDEALNQMGFDS
LATIEFRNELA-KTGIKVSLQKLVMGASIAEIAADTETQ-----------
>tr|A0A0E4HHQ7|A0A0E4HHQ7_9BACL Beta-ketoacyl synthase OS=Paenibacillus riograndensis SBR5 GN=PRIO_5823 PE=4 SV=1
-------------------------------------------------------------------------YINLMNEIK--DRNIRQILHLSSITGE
AAA-TCADLADQQNRSLHSLFYLAKSISSNKINIDVVLISDNVTEVTHEQEINPLGAALFGLGTVLTQEFKNIHCRALDVDRETPAEL------IS-EIQ
RIESKYQVALRSGKRYTCELDRHEPEHEQ---GLEIKEQGVYIITGGTGGIGLEIARYLAKN-AVHIALMNRS-KLPEAASWDSRKLQAIKDIRESGSEV
SCYSCDIADPDQVNEVVQDLKGK-YGRIHGIFHCAGVAGEGFTFRKPKAVFNEVVSPKVTGTWILDQATREENLEFFILFSSINAIFGGSGQGDYTAANA
YLDSFSYSRN-KRGARTISINWPAWSEVGIAADYG---TEESSVFHMLTVKQALNFMDEMAAGGIHAIPGSLNRPLLA----------------------
------------S-VQDQ--------LPFTLSGAIRSKLKGTGPEIEAAGDIV---LKG--K-GTEYSETEKNIAQMYSLILDMHELDLYESFNAMGGDS
IMATQLLKLIDKKYPDIVDISDIFTYSSVVELAEYIDRE-----------
>tr|A0A0K6LN12|A0A0K6LN12_BACAM Polyketide synthase PksN OS=Bacillus amyloliquefaciens GN=pksN_2 PE=4 SV=1
-------------------------------------------------------------------------YVQLLHSIN--DQNISSIIHMSSISRQ
GTE-SLTDLEDMQNKGVYSLFRLVRGLSKNKMNINLHLISDLVTEVSEENTINPLGAALFGLGRVISQEFQNVSCKAIDIDEHTSPEI------IS-ELR
TKGKHYQVAFRDGKRYISRLDTVEPIKHG---GMEIKENGVYMITGGTGGIGLEIAKHLAKH-NVNAVLLNRS-KLPDQSRWDCRKLKSIRAIESMGSKV
DCYSCEVSDLNSMEPVIEEIKQK-YGTINGVFHCAGVAGDGFLFRKEANIFKEVLAPKINGTWVINHLTRDVDLDFTILFSSINSIFGGAGQGDYTAANA
YLDSFAYMQN-KQGKNTLSINWPAWDEVGIAVDYG---TDESSIFRLLTVERAISVLEEIASNKLNIIPGTLNMKLLA----------------------
------------F-AKDE--------LSFELSEQIKNKLIDKN-RRTDTEDIV---LKG--K-GELYSDTEKSIAQMYSMVLDMQELDLYESFSAMGGDS
IMATQLLKLINQQYPDIVDISDIFTYSSVVELSEYIDKQ-----------
>tr|C3HA42|C3HA42_BACTU Beta-ketoacyl synthase OS=Bacillus thuringiensis serovar huazhongensis BGSC 4BD1 GN=bthur0011_53590 PE=4 SV=1
-------------------------------------------------------------------------YSNLINEVK--ERNITKIIHLSSMTNG
EAI-HFSNLKELQHNGLYSLFYLVRGISVNKVNIDLILISNNVTEVTNEKTINPLGAAMFGLGSVISQEFSNIKCRAIDVDDHTAITS------II-EIK
SEDKHYQIAFRNNIRYISELDVVEHNPGA---GLEIKENGVYMITGGTGGIGLEIAKYLAKN-KVNIVLLNRS-KLPEMELWESRKLEIIRSIQGMGSEV
KCYSCEVSDFSSMSKVIGEVKEK-YGKINGIFHCAGVAGEGFIFRKQEAVFKEVINPKISGTWLIDYLTKDENIDFSILFSSINSIFGGAGQGDYTAANA
YLDSFSYYRN-KKGKKTISINWPAWDEVGIAVDYG---TDEFSIFKLLTVNKALSILDTIVDNALNVIPGKLNMDILE----------------------
------------V-AKGE--------LPFELSISIKNKLKEAKSLKNSTSDVV---IKG--K-GEYYSETEKNIAQMYSMVLDIPELDLYESFSAMGGDS
IMATQLLKLINQKYPNLVDISDIFTYPSVVELSEYIDGE-----------
>tr|W4B283|W4B283_9BACL Beta-ketoacyl synthase family protein,phosphopantetheine-containing protein OS=Paenibacillus sp. FSL R7-269 GN=C162_28824 PE=4 
-------------------------------------------------------------------------YINLMNELK--GRNIRQILHLSSIAGE
AA--TYKELEDQQNRSLYSLFYLAKSISSNKINIDVVLLSDHATEVTQEKKINALGAALFGLGSVLTQESKNIHCRAVDVDNETPAEQ------II-EIQ
RIEPKYQVAFRNGKRYTSELDLYKPENEK---ELEIKENGVYIITGGTGGIGLEIAKYLAKS-SVHIALINRS-KLPEAELWESSKLKTINEIKESGSGV
YCYSCDITDPDQVNEVVQELKMK-YGSIQGIFHCAGVAGDGFIFRKPEAVFKEVVSPKITGTWVLDQATKEENLDFFMLFSSINAVFGGSGQGDYTAANA
YLDSFSYSRN-KRDARTTSVNWPAWGEVGIAADYG---NGDLSVFHMLPVKEALKLMDRMAAGDIQAIPGRLNCPVLA----------------------
------------A-AQDQ--------LPFALSAAVRDQLRDVGAERKAAGDVV---LKG--K-GADYSETEKNIAQMYSSILDRHELDLYESFNAMGGDS
IMATQLLKLIDTQYPDVVDISDIFTYSSVVELAEYIDRE-----------
>tr|W4BBJ4|W4BBJ4_9BACL Beta-ketoacyl synthase family protein,phosphopantetheine-containing protein OS=Paenibacillus sp. FSL R5-192 GN=C161_02750 PE=4 
-------------------------------------------------------------------------GGELFVALG--ETSISDIVHLFAVPAS
TEIRTLQALEQSQQKGVYSLFYLIRALIEHGSALNMMLVSEQVYEVTGESRLSPEAASLYGLGKVLALEYPHITCRSIDLDESTGVAE------LL-EMG
SQNQSYTSAYRNGVRYIEELGEVPANEDS---PVHIQRDGVYVITGGTGGIGQEMAKFFAQA-DVKLVLIGRT-PVPVRSEWEAALLHNFLAIEQQGSEV
SCYAADVSDYAAMQDVLADVREK-HGSITGVIHGAGVPAVGYLIRKTQETFDEVLHPKVQGAWILDQLTRQDELDFMVFFSSGLSLSSEVGQGDYSAANA
YLDALSYSRS-KSGLKTLSINWSSWKEAGMSVDYG---NV-DAITKALPTEQATAGFFAALNKEVRVLIGEFTYHPRF----------------------
---------A--KALLTK--------FPFRFSEEMTNRLKEAERNKSANAHVE---LKG--KDGEDYNSIERQIAGMYNEVLGFEELDIHDSFFDLGGDS
ILLNRLFSLLEDAYPGKMKLIHLFSYTSVHALSQFVMTK-----------
>tr|E0I7G9|E0I7G9_9BACL Beta-ketoacyl synthase OS=Paenibacillus curdlanolyticus YK9 GN=PaecuDRAFT_1593 PE=4 SV=1
-------------------------------------------------------------------------GLELMKELQ--HKEITDVVVLSTLPGM
KRPGTLHEVRGELQEGVYGLFHIVQALDHYFARVRLLIAVSGASEV-AGDEVRPTSNATIGFAKAVHWEYPNIRCRTVDIGRRTSLNA------LL-EIR
GHGADFGCAYRDGKRYVELIRPLRVQPDR---TAGIKEGGTYIITGGTGRLGLRLAAHIADF-PVRAVLLSRS-GLPDRAEWGKNKIRAVVQIEENGSTV
RVIPCDVSDETIARAMLDSLYAE-YGRVDGIVHCAVSDENIRIAEMTDEHLSASFASKIEAAWIVADSSRQWEMDFFVLFSSVMTLVSGQANAIYTAGNS
YLDALPYAVR-RAGM--VTINWPEWKNIGLDESKT---EEERSIFLKLDASEGLRLFDAAIASGQRLIAGSMNYASEA----------------------
---------F--E-LIDY--------LPFQVSEDILAQLPKRAPAHSAPPKVR---LTG--RSSGQYSVTEQLLAEAWSTVLGYEEVNIGDNFFEIGGSS
ISAVRIAIELMAH-DIVLEAPEILRYQTVEKIAGFIGGA-----------
>tr|B8I5I2|B8I5I2_CLOCE Beta-ketoacyl synthase OS=Clostridium cellulolyticum (strain ATCC 35319 / DSM 5812 / JCM 6584 / H10) GN=Ccel_2385 PE=4 SV=1
-------------------------------------------------------------------------YEKLLEVLS--CENITRVLYLTPREKE
IEINSPEQFESNLDDGLYAFFRFTAAFARKFARVEFVLVSRPVNEIIHE-DIYPDDSAITGVGMVLPFEYPGFSSRCIELDKETPYAN------II-EIR
SQKKYFKVAYRKGKRYVEQLQSIQKDMKS---NIYFKENGTYVITGGLGDIGTKLAVHVARH-NANIILIGRT-KLPEREYWKSGKLEAMEKLEKFSCKV
AYYTADISLERELSEVLEAIRNK-HGKINGIIHCAGVGANRIIGEETEETFREVLKPKLRGTWLLDKLTRKDNLDFFIMFSSAITLIGGRGSSHYTAANC
YLDAYSFKRK-TSVTKYMALDWAPWYRSDSIGDKK---FEEKHIFKVLPQAAALKAFDETICLNLKVIAGELNMDAAL----------------------
---------F--K-LEDF--------LPFNFSSELKEKIDAHQ-EKSHKQELT---LTG--KSSGEYSEAERKIAGIWGSVLGYKQLSIYNNFFEMGGDS
ILAASIHERLKKEFSQNISIADIFAYPTIAKMAEYISGF-----------
>tr|A0A0Q4QZH8|A0A0Q4QZH8_9BACL Uncharacterized protein OS=Paenibacillus sp. Leaf72 GN=ASF12_16665 PE=4 SV=1
-------------------------------------------------------------------------VDKLMVDLV--GRPVTHILHMSGLSKS
AAPETLEELEQTQQYGIYSLLYLTRSIMRHDPKRHMLLFTKLLHAATREAELSPEWATLVGLGKVIPQEFAQIVCKAIDVDDSTPVDA------IW-ELE
HFTKQYHVAYREGCRHTEEYGPIDPLKEA---ETAIHDTGVYLITGGTGGIGLENAKYLAKA-NVNVALVNRS-QLPPKEEWAIRKIQKLQEIEAMGGRI
TLHSADIADYAVMAALIGGLREK-FGRINGVIHGAGIAGAGYLFKKDLNIFKNVLEPKVAGTWILDRLTRQDQLDFFIMHSSGVSMVGEAGQGDYVSGNA
YLDAFAAYRR-KQERHALALNWVSWKEAGMSVRFG---NV-DSFYKALPTVQAIESMDTALQRNMRVLIGEMNESPEY----------------------
---------L--S-LLLA--------FPFHLTEELNDRVSGLLNNSTKPSKAA---LRG--KQGDGYNAVEQEVANIFSTILGYPEIDIHDTLFELGGDS
LLLMRIHKLIDTEYPGKVTITDMFEFPSVQRLAQHINKE-----------
>tr|H2JIP6|H2JIP6_9CLOT Beta-ketoacyl synthase family protein,phosphopantetheine-containing protein OS=Clostridium sp. BNL1100 GN=Clo1100_0476 PE=4 SV=
-------------------------------------------------------------------------DGEVFDAFS--DRHIDYVFHIASLEEN
NED-TFENLHRSIDVGIKSMFVFLQSIAKHQVKN-ITSCIDNSVTVNNEEETKPLNRALSGMLKSASREFDNIRFKIIDIDEETDTSV------VL-EIL
YGEDMVLTAYRSNCRFVEAFAEHV---RR---KISIKNDGVYVITGGLGGVGLVIAKQLAMNGNVKIALLNRS-KAPQ--EALINSLEKIYEITGDKNSL
EVISVDISNIESVSREISLLREK-YGKINGVIHCAGVAGKGFLLRKTWDEFENVLRSKVYGTWIVDKVTENDDLDFFIMCSSISSIFTSSGQSDYSAANS
YIDSFAELRS-KRNKNTLAINWTGWKETGMAVDYK---NQGESLFKFIDNARGQEAFEYALGSTQRIIIGELNYEMIQ----------------------
---------K--SRNFLD--------DLIVFSNSIENKLRQYQEDEQEEIKIS---VLG--KSNGDITSTEYQVAKAVAKTLRFEEVNIYDKFFEMGGDS
LLAASFKKELDKLFPDVVDITDVFTYVSVYEMAKYIDSK-----------
>tr|A0A089KQA4|A0A089KQA4_9BACL Phosphopantetheine attachment protein OS=Paenibacillus sp. FSL R7-0331 GN=R70331_07385 PE=4 SV=1
-------------------------------------------------------------------------FEGWLSLFP--KERIKYIVQLASLSME
DVQ-SVHDVVYETSIILKSTFDLIKALLKQDVEIRLVLMTSNATFVTDEDQVYPIYRALAGMGASIGEEYANIKTRTVDCDRNTELAS------LL-ELF
YDEKMYAVAFRDNKRYVEQLDTVAYSEEK---KLQLKDQGTYIITGGLGGMGLAICRYLFVNPAIRVILLNRT-FSREMFKALQNKIDEVNKLWSDGKDL
EILQVDIADYGQLRETLQDIRDQ-YGAIDGVIHTAGVAGDGFIMKKDWETFEAVLRPKVYGTWMLHELTRDDQLSFFVMCSSFASLFGAAGQSDYIAANA
YLDSFTYYRR-SLGIPSLTINWTGWSESGMAVANG---NANGMYVHFVKDTEGANAFAYALQTGLRVLVGDVNYSVLA----------------------
---------S--ESQGYG--------EKIKFSEKIEKKRGTATTTERDLHDIV---VTG--KSMDKLTEIEKHVISAWVKTLSVDEVDLHDKFFESGGNS
LLAAYLHKELNKAYPGVTAITDIFVYSSVLDISNYIESK-----------
>tr|A0A0M0WX90|A0A0M0WX90_9BACI Phosphopantetheine attachment protein OS=Lysinibacillus sp. FJAT-14745 GN=AMS59_10480 PE=4 SV=1
-------------------------------------------------------------------------SDSLLSSLP--KENIKHIVQMASLVNP
VLQ-SVEDVVSETKLVLKSTFELVKALLNHNVEIRLTLMTSKATLVTDEEQIHPMHRALIGMGASIGEEYANILTRAIDCDGHTDEGS------LL-ELL
HDEPMYAVAYRGNKRYIEQMDTLPYE-EQ---KLELKDQGTYIITGGLGGMGLALCRYLFVNPEIHVILLNRT-YSREAFEALQNKIDQVNKLWTEGKNL
DILQVDIAEYDQIKATLQDIRDR-NGAIDGVIHAAGVAGDGFILTKDWETFEEVLSPKIYGTWVLHELTRDDQLDFFVMCSSLTSVFGTAGQSDYIAANA
YMDSFTYYRR-NQGVPSLTINWTGWSESGMAVSNG---NVNGMYVHFVKDTEGANAFAHALQTGLRVLVGEINYSVLA----------------------
---------S--GGQTYA--------KKIRLSEKMTEKQGATATANRDIQNVV---VTG--KSMDKLTEIEKNVIAAWVQTLGVDEVDVHDKFFESGGNS
LLASYLHKEMNKVYPGMTAITDIFVYSSVVEISSHIESK-----------
>tr|A0A017SV21|A0A017SV21_9DELT Malonyl CoA-acyl carrier protein transacylase OS=Chondromyces apiculatus DSM 436 GN=CAP_1336 PE=4 SV=1
-------------------------------------------------------------------------G--LHAALQDSARPFDGIIHLWSLDAA
LTGASLTPLTAARDLCVDSLLEIVQAAIRPGVPPRLWVVTRGAQPVGAPQPASPTQALAWGLGRTIPHEHAELRCTCVDLGTDPAD--EQEIEALL-ELT
ADDAEDQIALRGPTRFVARLAPADAPKPA---PSPVHPHATYLIVGGLGGLGLALARWFVDQGARHLVLLGRS-PASPPA------RAAIAALERDGARV
VVAQGDVTDEARLRALLADLARD-MPPLRGVVHAAVVLDDGVLLQQTPARCATVLAPKVEGAWNLHAATLGAPLDFFVLFSSGASLLGSPGQGSYAAANA
FLDALAHHRR-ALGLPALSINWGVWAEIGLAAAQERGARLEASGFESIRPADGLALFGDLLQRALQVGAIPFDLARWR----------------------
---------VFYPRAAA---------S-PLFAELALRVDGT--ATPTSDFRAD---LLA-APAAERLPLLTARVEQLVARVMRPDAVDRQRPLGTVGFDS
LMAVELRNHLEASFGLRLPATLLWSYPTIDAMAEHLLGK-----------
>tr|A0A0C2D3B5|A0A0C2D3B5_9DELT Malonyl CoA-acyl carrier protein transacylase OS=Enhygromyxa salina GN=DB30_06511 PE=4 SV=1
-------------------------------------------------------------------------Q-------------ATDIVHFAPTPRA
DADQSAAATLEAGTAACEGALAS----H-RAVDQRIWLVTQAAAPSL--GLVDPMLSAVWGLGRVMQIEGGKRFARSVDLDPAAGVVG---MATLA-ELG
IDDQEPAVAYRDGQRLAARLEQRTPAHSP---MSRLDPGASYLITGGLGGLGLRMAAHLIDLGARRLILLGRT-GLPPRERWGQARVAAVRALEARGAAV
HVVALDVADEPSLRAFAQRWRCEQRPAIRGLVHAAGVQHPLALAQLGVEQLRACLRAKLAGGWALERVF-GDQLGFSLLFSSAATVLPSPLLGAYTAANA
CLDGLATHAR-AAGRPVTAVSWGLLAAGEMASRQL-AARGELHGFDDMDPAAAYAALERALAAELHVGVMAIDWRAWL----------------------
---------SRHAELAE---------L-PYFEALARFGDGAARLAASSGSLAA---LRL-GDADGRRERLGVYLREQLGRVLQGATIDPGVALTRLGIDS
LMALELRNRIEAETGAAPAVVELLRGISLAELIELVDAQ-----------
>tr|B9ZUJ9|B9ZUJ9_CHOCO Polyketide synthase OS=Chondromyces crocatus GN=cndD PE=4 SV=1
-------------------------------------------------------------------------G--IQGALRHDALPCHGIVHLASLDAD
AA--EPRSLSAARESGFDTLLEVVQVAANASLPPRLWVVTRGAQAIGPAPAVAPDQALAWGLVRTIQHEHPEFRCSGIDLGVDPAS--TPEFDALV-ELV
ADDVEDQLALRGDTRLVARFARRDTSARP---PAALRENATYLIVGGLGGIGLRLTRWLIEQGARHLVVVGRS-PITPAA------RSTLDALESSGARI
VFAQGDVADPVHLQGIVAKMKRE-MPPLAGIVHAAVVLDDGVLRQQTAARCARVLAPKVEGAWNLHLATLDTPLDFFVLFSSGASLLGSPGQGSYGAANA
FLDALAHHRH-ALGLPALSINWGVWAEVGLAAAQARGARLEASGFESIQPDDGFALFGELLGRP-QIGAIPFDFARWR----------------------
---------RFYPQAAA---------S-PLFAELAEVPGDEPEPTSPDEVRQL---LLD-AAPTERAPLLAARLQRTVARVMRPTEIDCQRPLGTLGFDS
LMAVELRNQLEASLGIRLPATLIWSYPTIDAMTEHLLTK-----------
>tr|A0A0K1EJE0|A0A0K1EJE0_CHOCO Polyketide synthase OS=Chondromyces crocatus GN=CMC5_048540 PE=4 SV=1
-------------------------------------------------------------------------ADGLLDAIEDLPQPLHGVVYLRGVDAQ
LAPAPDTALATDASRVLAGALHVAQALARRERTPHLWLVTCGAQRLGATAPVAVAQAPLWGLGRTLALEHPELSCKLVDLAPPSAAADAPLVSALA-ELL
TDGPDEEIALREGTRHVGRLAQRPLSRPD---ATPIRNDGTYLITGGLGGLGLSAAAWLVGRGARHLVLVGRK-GATTPAQ-----IDALRALREAGAHV
VTAQADVASRAQVAAMLDTAAVA-MPPLRGVLHAAGVLDDGTLLTQRRERLQRVFEPKADGAWHLHTLTRHLPLDFFVLYASAASLVGSAGQSNYAAANA
FLDALAHHRR-ALGLPAVSIDWSAFAEVGMAADLTASARNAHAGLRLIQPDEGTAILGALLDAGAQIGVIPLEGGQWS----------------------
---------RHPRAATS-----------TRLAELVRGGPRA--AAPAVSIDAA---LSA-APEEARAAMIERVVVEQIASVARPAQIERETALTSIGLDS
LMGLELRTRLEAALTVRLASTLVWKHPTVAALAAHLHTE-----------
>tr|C5A931|C5A931_BURGB Polyketide synthase OS=Burkholderia glumae (strain BGR1) GN=bglu_1g23020 PE=4 SV=1
-------------------------------------------------------------------------DAALRDA-CRLDAGPAVLLYAWPAADE
SG-DALAALGAAYRR-VANIWREVQQT--RWTAPAFCIVTRAAQRVPVEVRVSPFQAAAWGVARSLMHESGDHAVLAVDLPSPDAASS---AAALAVKGA
AASGETQFVAHGEALYVPRLVAREAGA---------LARGAYLVTGGRGAIGTRLIERLIRNGVPKVVSVSRA-VPADGER-----ARLASIADRHGASV
EFVAADVTVAADVDALVHALEADRAHPLVGVLHAAGTLDDGLLATQPSAEVIKVLAPKVAGTLNLHRATDHLRLQHFVSFSSIVACIGSPGQCAYAAANA
YLDALTALRN-QDGLPGHTMNWGLWGGNGMVDQLDQLRRIASFGLTPIEPDAALGLFDRLVAEPDHTQIWNVEVETLI----------------------
---------RRSPSRAM---------G-ALLSELATPALAADRAASGPGLRER---MAG-LQGEARARLLRGHLSEAIAATLHVERISPDIALIELGLDS
LMAADFRNGLRSELGVEVPFGRLLEGATIDDVVRTIVAT-----------
>tr|A0A095EQS3|A0A095EQS3_BURCE Short chain dehydrogenase family protein OS=Burkholderia cepacia GN=DM43_4278 PE=4 SV=1
-------------------------------------------------------------------------DAALDDDALGPNARPAVLLYVWPSIGD
AE-DELAAVGTAYRR-FANFWREVQST--RWPAPTVCIVTRAAQHVPIDVRVSPSQAAAWGVARSLMHESGDIPVCVVDLPAPDATSC---ASALTLAGA
AATGETQFVSCGDTVYVPRLVARDAGG---------LARGAYLVTGGRGAIGTRVIEQLIRTGVPKIVSASRQ-VPTDSER-----ARLASIAGAHGTIV
EFVAADVASAADTDALVHALEADSAHPLVGVLHAAGTLDDGLLATQAMTDVLKVLAPKVAGTLNLHRATAHLPLRHFVSFSSIVACIGSPGQCAYAAANA
YVDALTALRN-QDGLPGHTMNWGLWGGNGMVDQLDQLRRIASFGLEPIEPDAALRLFDTLVAEPDQTQIWNVEVDTLI----------------------
---------KRSPSRAM---------A-TLLSELVPPASPANRTGTGHGLRER---IAG-LPDDERMQLLRGHLTDAIAATLHSARIAPDIPLIELGLDS
LMAAEFRNALRSELGVDVPFGRLLEGATVDDVVRTIVAT-----------
>tr|A0A0K1EIL6|A0A0K1EIL6_CHOCO Polyketide synthase OS=Chondromyces crocatus GN=CMC5_048560 PE=4 SV=1
-------------------------------------------------------------------------ADALLRTAFADGVPCAGILHLWALEAT
PERTTLDSLDRDQRRICGSALHLVQGLTRSNLPPRLWFVTRGAQAVDSGRAVSVAQAPLWGLARTIWLEHKELPCSRVDL--DPDA--PPEVDALV-ELL
SGVREDELALRATGRHVGRLGRSATLAAG---ATLVRADATYLVTGGLGGLGLSVAAWLVERGARHLALLGRN-GAATAAQ-----IEAVRALEAAGAEV
RIAALDVADRAQLAQLLDDLQRT-MPPLRGVLHAAGVIDDGLLAAQDLTRFHRVMQPKIAGSWNLHELTRSAPLDFFVLYSSAAALLGAPGQGNYAAANA
FMDALAHHRR-ALGAPALSIAWGIFSEAGIAAR-ATDSRLAQQGFGHLTPAEGASLLGRLLGGGAHLGVARVNLRQWV----------------------
---------AFYPQIAS---------A-PRLARLVGRAAVR--PTGDEGILAA---IRA-RTPAKRQALVEQLLCEHVARVVRPARIQPEAPLKGLGIDS
LMGLELRNRLESILGITLSATLVWTYPSIAALAAHLLEK-----------
>tr|B1GYG0|B1GYG0_CHOCO Polyketide synthase OS=Chondromyces crocatus GN=ajuF PE=4 SV=1
-------------------------------------------------------------------------GAQLLAEAQGGDPPLTGIVHLWSLDTS
A---SLEALWHAQELGCASAVLTVQALLRSEAPPRLWLVTRGAQAATSDHALAIAQAPLWGLGRGLLVEHAEIFGGLVDL--DPNT--PPDVELLT-EIL
APDREQQLALRAGMRRALRLLHAQPLDRT---PISLRPDGTYWITGGLGGIGLEVARWMVDRGARHLVLTGRR-PPEGPT------EAVVHALEQRGIRV
AVIASDVAQPADVARVLTEIDHA-MPPLRGIVHAAGVLADRLLPQQDLESLREVLSPKIAGAFNLHEQTAERPLDFFVLFSSASGWFGAHGKAVYAAANT
FLDALAHHRR-ARRLTALTVSWGLWAGVGMAQG--EANRWQARGVGLIVPERGLDRLGRAIAVDRELG---VFFYDWE----------------------
---------RFFSAAAVE--------PPPLFDTLLAATPRRAGSPGRLALARA---LEQ-ALPGEREATLQRLLRGEVAAILGPAAPDPRQGFFEMGMDS
LMAMELKRRLEIGLGISLQASTIFNFPTIEALSGRLLAA-----------
>tr|A0A0Q4AWI7|A0A0Q4AWI7_9ACTN Polyketide synthase family protein OS=Frankia sp. CpI1-P GN=FF86_101838 PE=4 SV=1
-------------------------------------------------------------------------GVRLVDDLGDV-GEELQVVHLWSLTGA
AEPDSVEAALRAQNAGCMSAVRVVQALVEARSPTRLWLVTRGAVQPTGTTPLAVGQATLWGLGRSLQQEAAAVWGGLIDL--DPAA--EPAVAALLLEAA
DHRAEDQIALREGRRYVARLVHTRLPQPR---PAVLRREGSYLITGGFGGLGLEVARSLARRGARRLILVGRT-PVPPREQWAGRRVAAVRELESLGASV
TVESFDVSDEAAARAFLERHERECRPAILGVVHAAGAGDVAPLTDLEPDDLEWCLRPKAMGAWVLDRLFADRPLDFFVLFSSTSSILSSPFVAAYAAANA
FLDALALQRR-NAGRPGLSINWGIWERTGMAARGA-ATPGHSRGMGVLRPDQALRVLHRLLGHDLQVAVVPVDWSEWG----------------------
---------HRYQAVSL---------S-ALLSELLDAPAGAPAPGRRLPARAD---LLA-LPAQQRADALATRLLLATAVTLRPSAVGLDRPLIELGLDS
LMAVELRNELEGRLGVSLPISVFLRGATVQALAERIVDA-----------
>tr|J7H193|J7H193_9ACTN Type I polyketide synthase OS=Streptomyces sp. CNQ-418 GN=mpy6 PE=4 SV=1
-------------------------------------------------------------------------ANGLLNDWV--SEHPCRVLLLSGLDAP
RDHTDAWGLEEYAARGDLLAVELVRLLAEREDEATVTLVTRGAMPAGDELVTTPSAHTLWGLGRVFALEHPERWGGAIDVAPDPAADDTTEIERLV-ALE
RTSTEDEQALRGPDVYVSRVLPREPEPRA---PPPVRADGSYVITGAFGAIGLSLADWLARAGAGRLVLLGRT-PLPDRTTWNRNRIRAVRELERLGVEV
TVVTADVADEATMLAVFQELNGH-PLPLRGVVHAAGVSQPQFVRDVDADTYRAVWRPKVIGGWLLHQLTRTAELDFFLGFSSIAATWGSQHLSSYAAGNA
FLDGLALHRR-GQGLPALSVAWGPWELESNLFDEEVMNFLTSTGLFPLSQDQCLRLLGGLLSGPRQQVVCAVDWSIYK----------------------
---------PVMEARIE---------R-PILRGIEFSDDTG--DAETDALIKR---LRQ-DTPDARTERVTGLLRDVVADVAGADTVERDADVMGYGLDS
LMVMDVVRQCQRRLGVSVKASQLFERTTLGDWADLVDQR-----------
>tr|L7SVW8|L7SVW8_9ACTN PrlP OS=Nonomuraea spiralis GN=prlP PE=4 SV=1
-------------------------------------------------------------------------A--------LAEGRPHRVVVLTGLDAP
DDEADEDALVAFRDQAELLAVEVVQALRDR--GVTVHLVTRGAVPAAGRRQHRAAAAGLWGLGRVIALEHPGLWGGAVDLDPAGPADGTGLL---D-AL-
VHSAEDQIALREARALVCRLVRRPLPAQA---APPIRADGAYLVTGAFGGIGVTVARWLAGHGARRLVLLGRT-ALPERERWDTERIAVVRALEALGAEV
TVEAADVADAAAVRAAVARLEAG-GVPLRGVVHAAGVSRPQVLAEVDRAGYAAVWRPKVLGGWALHRATRESELDFFLGFSSIAAAWGSLYLAGYAAANA
FLDGLAQDRR-ARGLPGLSVDWGQWELPSKLYGADVRSFLAASGLRALPAGQGLRLLGALLGADRQPVVCAADWPAYK----------------------
---------ATLEIRGP---------K-PVLEQVEAAQAAE--AGEAAPVLEE---LRG-CPPDERPAVVSGYLRDQLAQILGRSRLDTEFRLLDLGIDS
LMVMELIRRVRRDLRIDCPAKDFFAT-DAAEWDTLLLRQ-----------
>tr|A3R4U3|A3R4U3_9ACTN Polyketide synthase OS=Streptomyces sp. UC 11065 GN=dox24 PE=4 SV=1
-------------------------------------------------------------------------AAALLERWRGAAATADRVVLLSGLDAP
EEAADADTLVEYRDRTELTLVAVVQGLLAREDRATVSLVTRGTVPAPEQAVSSPFGNTLWGLGRVVALEHPEHWGGAVDLDGSGPL--TDDIPGLA-ALL
DVRAEDQQALRGGTRYAARLMPHRLGQRR---TPRVRQDGSYLVTGAFGGIGQVLSRWLAINGAGRLVLLGRT-PLPPRADWDRERIALVRDLEATGAAV
EVVAADVSDVGQMLPVMERLAVD-ARPLAGVVHAAGLSVPQFLRDITPADYDAVWRPKVVGGWLLHQLTEGADLDFFLGFSSIAATWGSQHLSSYSAANA
FLDGLAEYRQ-GQGQAALTVSWGPWELESNLFGEDVLAFLMSTALRTLSAPQCLKLLGALLAGPHQAVVCAADWATYK----------------------
---------PVMEARIE---------R-PLLRTLEVVEDYG--DPA-PVLEEL---ARA-GGPRERGRRLVGYLRDVLGEVLSADGIEPAADVMSHGLDS
LMVMEVVKRCKKDLRVSVRPNQLFERSTLEDWAELLGSE-----------
>tr|K4R1B2|K4R1B2_9ACTN Polyketide synthase OS=Streptomyces davawensis JCM 4913 GN=pltC PE=4 SV=1
-------------------------------------------------------------------------A-PDLDDWLPDGVAPHRVVLLTGLDAP
RDAADAESLTAFRDRAELAAVALVQGLTARAARTGLSLVTRGAVPALGQGVTSPFAGTLWGLGRAIALEHPEHWAGAIDLDPQAGE--TDEGSALA-ALA
DTAAEDQQALRGEARRVARLVKFPLTARR---RPTIDRLGTYLITGAFGGIGQALARNLADSGAGKLVLLGRT-PLPPRQRWNRERVDFVSALEETGVLV
DVVAADVNDIEDMLPVIQGLATG-LMPLRGVVHAAGTSVPQFLRDIPPSDYDAVWRPKVVGGWLLHQLTEGLELDFFLGFSSIAATWGSQHVTSYAAANS
FLDALAEYRQ-AQGLTALTVSWGPWELTSNLFGADVVEFLTSTGLRMLSAPQCLRLLDALLAQGAQAVVCSADWSVYK----------------------
---------PVMEARAD---------R-PVLRTVEIDEGIG--TST-AVLQAL---EGA--DAAGRATVLTGYLQQVLGEVLAPESVLPEADVMSHGLDS
LMVMEVVKRCKGDLGISVRPSQFFERTTLEDWVRLLDTE-----------
>tr|A3R4R5|A3R4R5_9ACTN Polyketide synthase OS=Streptomyces vitaminophilus GN=pyr24 PE=4 SV=1
-------------------------------------------------------------------------ATELLARWRVPTDTADRIVLLTGLDAP
EEAADAEALVEYRDRTELTVVSLVQGLLAREDKATVSFVTRGTMPAQRGDVSSPFGNTLWGLGRVVALEHPEHWGGAVDLDPAGPL--TDDVARLA-ALL
DVRAEDQQALRGDTRYVARLVPHSVTQRS---TPPVRSSASYLITGAFGGIGRALSRWLAINGAGKLVLVGRT-PLPPRTDWDRERIDLVRELEATGALV
EVAAADVCDPAQLLPVMEDLAVD-SRPLAGVVHAAGLSVPQFLRDITPDDYDAVWRPKVVGGWLLHQLTEGAELDFFLGFSSIAATWGSQHLSSYSASNA
FLDGLAEYRR-GLGQAALTVSWGPWELESNLFGEDVLAFLMSTGLRTLSAPQCLKLLGALLLGSEQAVVCAADWATYK----------------------
---------PVMEARIE---------R-PLLRTLQIVEDFG--AGS-PVLEEI---GRA-AGPRERVERLVGYLRDVLGDVLSADAIEPEADVMSHGLDS
LMVMEVVKRCKKDLRVSVRPNHLFERSTLVDWADLLSGE-----------
>tr|A0A0P6YGV2|A0A0P6YGV2_9CHLR Uncharacterized protein OS=Herpetosiphon geysericola GN=SE18_01980 PE=4 SV=1
-------------------------------------------------------------------------A-SDLRAWLKLQAKYQHIVCLWPLAAN
NAP--AAA---AIH-QSSAMLSLLQTMSD-PHNPRLWCVTRGGQAI-SNEVVNLAQAPLWGMVRSAALEHPELSPTLVDLDPNQQANE---ASQLA-ILL
QRSNEHQQALRNQQALVARLQKRPAPALS---TISLTSDAAYLITGGSGGLGLEIAHWMLAKGARNLVILGRR-PLQPANASQSQLLNALHDLEQAGANV
HYAAINVADQAALAEFVQHYRAETGLAIRGIVHAAGVLDDQMLYRMEPSALTSVFAPKVAGAWALHEVFSAEPLDFMIFCSSLAASFGSVGQAHYAAANS
FMDSLAAYRR-SQGLAGLSINWGPWARVGMAARLN-PQMFEAHGVQLLEPSQALIAMEQLLSDQAQTTIAEIDWATWL----------------------
---------KTNPVGAA---------L-PFFAALMPQTGLEQATNHEHEFRRL---VQQ-TEPSDRQALITQQLKQLIAKVMQPAKLASQLPLHTLGLDS
IMAIELKTSISKQLGVTLSVAYLIQGPSIDEIGANINQQ-----------
>tr|A9AYS4|A9AYS4_HERA2 Beta-ketoacyl synthase OS=Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785) GN=Haur_2412 PE=4 SV=1
-------------------------------------------------------------------------A-NGLGDWLQLQANYQQIVCLWPLAAS
NAP--VTS---ATQ-QSLAMLTLLQTLSD-SGTPRLWCVTRGAQAVLDHEVINLAQAPLWGMVRSAALEHPELAPSLIDLAPMAESNE---ASQLA-TLL
QRANEHQQALRNQQQLVARLQQRPIT-ST---TLKLSNQAAYLITGGSGGLGLEIAHWMLAKGASNLIILGRR-PLQPSHNAVSQLVNALSQLEQAGANL
RYAAINVADQAALAEFLQQYRAETGLAIRGIVHAAGVLDDQMLYRMQPSALTSVFAPKVAGAWALHEVFSQEPLDFMIFCSSLAASIGSVGQAHYAAANS
FMDSLAAYRR-SQGLVGLSINWGPWAEVGMAAKLN-PQLFEAHGVQLLQPQQALVAMEQLINDQAQTTIAEIDWATWL----------------------
---------KNNQVVAT---------L-PFFAALAPSTTIAQTLTQEHEFRQR---VLQ-TQPSERQALITQQLKQLIAKVMQPSKLDSQLALHTLGLDS
IMAIELKTSISQNLGVTLSVAYLIQGPSIDEIVANVNQQ-----------
>tr|A0A0F7ZT85|A0A0F7ZT85_9HYPO Uncharacterized protein OS=Hirsutella minnesotensis 3608 GN=HIM_07865 PE=4 SV=1
RFRFVINWQQIDTAASISGLGGSWGLLCPAGEVAWAEE-V----ESTLLLRSGLRQ---------LR---------RISGL-SDAQQLDGVLCLWDSDAK
DVPLAARKL-------TAAALSQVQEAAR--GLFALPIVWVT-RNAVGTSSSGIAAAPLWGLMRTAQAENPNLKLRLIDLDEG----PTGL--AALAPAI
MLPAEPQCAMRQGKVLVPRLQPFRPRAGLPSQGPLVRRDGAVLITGGTGGIGRYVARWLAAHGVRDLVLISRRGPEAPGA--EALVAELA----QLGAEA
ELVAGDVADVNSLRAILSRFGGS--RPLRGVIHAAGVLDDGVLSALTPQRCDTAFAPKADGAWNLHQLTQGMDLDLFVLFSSVSGIMGAAGQGNYAAANT
FLDALAYRRR-AEKQPATSVAWGLWTGEGMAANMSCLARYLRSGLDPLSPEDGLELLGQAARSGALTVAAAYNVQRLQECHNDGHEL----PPLLR----
---------SLIRTRHGRWQMRHGEGR------------------GQSESRGLRATLDSAA-PEEHPAITLVMVRLAVAQTLGFSSVDVDVPLRDMGIDS
LTAVLTRNQLAALTGLSLPAGIALQHPNLTTLSQFLLSQ-----------
>tr|A0A0F5NHF2|A0A0F5NHF2_9MYCO Beta-ketoacyl synthase OS=Mycobacterium nebraskense GN=WU83_02785 PE=4 SV=1
DWMYQLRWQPASLSER--AEAGSWLILSDGGITAETLRDLESHSQTCALVEPGLDNQDFERNSYRLDPTQPEFRLLLEDAFTDARPPCRGVVHLWDLLAA
PAADTSESLDSATTLGPVSVLHLVQALAA--GWSAPPRLWLVTGGSQVTEPVSIAQAPVWGMARTIEHEHPELRCTCVDLSVG----GGPE----FREVW
ADGRDGDVALRGGRRYVERLNHYDA--PEPTETVAFTEEATYLITGGLGALGLVVAKWMAEHGARHLVVMGRGGAS-ASA--QESLDALR----AGGTEV
IVAQADVAKADEVAAVIESIGESM-PPLRGVVHAAGIADDAILQCLDEQKLRKVMAPKVQGAWNLHALTSDAELDFFVLFSSAASLLGPPGAANYAAANA
FLDALAWHRR-AEGRPALSVNWGPWAELGFFTRSELQSYFAQYGVEAMSAADSLRALSSLLARSTQAVVLDIDWARWQPDV----------QPPLL----
---------AELGVAPSGDQPQ--GAT------------------ASGPGNGLSDELQGAT-PEERRRLLESYLCELAAGKLGLAP-DIQAPLNTLGVDS
LITLELRMQVERDLGVVVPVTKLLEGPSVASLAEWLCDH-----------
>tr|A0A0C2QT40|A0A0C2QT40_9CYAN Beta-ketoacyl synthase OS=Scytonema tolypothrichoides VB-61278 GN=SD80_11865 PE=4 SV=1
DWLYEVQWQQLPRDVELSDKAGTWLIFADLEGVGQTLAKLRSQGHKCILVYPGNI-YSLKEGTWSINPYSPVFELLFQEVLG-MELPLQGIVHLWSLEAE
WALDLTSSLEQAQIFGVGSVLHLLQALII--SASPLPRLWLVTRGAVPV--PGVAQAPLWGLGKVVALEHPELWGGMLDLAPN----STND----LAEIS
DSLGEDHIAFRNGSRYVARLVPKQQ--KQS-KQVALRSDGTYLITGGLGALGLKVARLLVSLGARQLVLLGRNTEK-DSV--QSTLRQLE----ELGAKV
IVQKADVSDEADMRNVLETIQATM-PPLRGIVHAAGILDDGILQQQSWERFSRVMAPKVRGAWNLHTLTKGLPLDFFVVFSSAASLLGSPGQGNYAAANS
FLDALANYRR-LQGLPGLSINWGPWAEVGMAASLARHQAANAMGLDSIAPELGLQVLKQLLQVSSQIGVLAVDWSVLRQQLSVSHQL----PPLLF----
---------ELFGKIKTQAE----TDV------------------LSAQQCDIVQQLQAAP-ASDRLALLTAYIQGEVAKVLKFAPPDPKQNFFDMGMDS
LTSVEFKNHLQNDLGRFFPSTLVFNYPNINALVQYLSQQ-----------
>tr|B1ZYK8|B1ZYK8_OPITP Beta-ketoacyl synthase OS=Opitutus terrae (strain DSM 11246 / PB90-1) GN=Oter_1961 PE=4 SV=1
GYTYEVRWPAEPLGVPAAPAAGRWLVLGPAPQ---ELESFDANGQTLER-------AEAFRGDWR-------------------------------GALF
WAGDEP---G------ESEAARLLR---A--MQTANVPLWIATRGAVATARVRLDHAPLWGMGKVYALEHPERWGALIDLPAD----PTAV--D-AELLG
HPAGEDQVAWRGGVRHVARLEPAPL--PPVSPLPVLRADAAYWVTGGTGALGLQVAQWLVARGARRLVLTARRSPG-VTA--LARIADLE----KAGVTV
RCLAADVAVEQDVRRVLAQVGAEL-GPVRGIVHAAGVVSRVSIAELTPEALADVLRPKLGGARALDAATAGHELDFFVLFSSIAALWGAKGQAHYAAANA
ALDALAQQRR-ATGRPALSVGWGPWSGGGMAGPEE-QALLARYGVSPLDPAVALAALDRALGGTAQVAVARVDWAVFKEFFELHGA------KPFL----
---------ALVGGRREPAA----AGR------------------LE----AELAALATAA-PEQRRGGMEAFLQQQVAAVLGFKDPEVRQGFFALGMDS
MMAVDLGRRLSQACGRTLSSTLVFDHASIHLLAAHLVET-----------
>tr|A0A0E3ZRR5|A0A0E3ZRR5_9BACT Uncharacterized protein OS=Spirosoma radiotolerans GN=SD10_02295 PE=4 SV=1
EHVYLPQWVSEPLQSPANPSKRTWLIFADKKGVGTELARFEQNGHKTIKVFNGNCTFKIDESTYQLDGQNPDLQVLLQDGVIHQ--QPNGFIYLWAADAD
TNARHSTAFP-----AYAQFLNIIRVVGL--PCTDHTPFWVVTQPVSSV--DSVSESPYWGFAKSAWLEYPQLKGGIITMDSQ----HGPA----VSELV
SQQSEDSVWFDDENRRVYRLKKAS---PLSESPLTLDRTGLYVITGGLGFLGIKFLQWMVAHGAQHIVLTTRKNIPPLAA--LKQVKAFR----QGGIDV
KVVTLDIASHDQLREFIASVKLDG-LLLKGVVHTAGDSEYRSIETIDPQAISRILQPKIVGGWNLHQVTKDADLHFFICLSSITAIWGGKNQALYAAANQ
FLDGLSIHRK-ALGLPGLTVNLGPIAGGGMAGDST--TMFEKVGIQAMDAEAIFPVISKLIASASQAVLARIDWDKFDAVYRMHAVS----PVLMM----
---------AKVPEPKHRDE----GG---------------------QMASESLKKLEALY-PADRHTYLLELLNDKVADVLGYRTVPLDIGLFDLGLDS
IMALSLKESLEKEFQVKLKQTVAFNYPTIHRMANYLMSE-----------
>tr|A0A0C2Q5J7|A0A0C2Q5J7_9CYAN Beta-ketoacyl synthase OS=Tolypothrix campylonemoides VB511288 GN=SD81_07450 PE=4 SV=1
DWFYEIDWQVKPRQVD--HKPGTWLILADSKGVGKTLAELHSRGHTCILVYAGDT-YKTQEGTWSINPSNPTFKRLFQEALG-SLMPLQGVVHLWSLEAE
LASKLTSSLEQAQTLGVGSLLYLIKELRF--NHESLPRLWLVTRGAVSV--PGIAQASVWGMGKVVALEHPELWGGMLDLAPH----TTDK--SHLAEIE
DSFGEDHLAFRNGNRYVAHLVRKQL--PEP-KKVVLRSDGTYLITGGLGALGLSVAQWMVERGAKQLVLIGRRIPS-SKA--QETLRQLE----QKGAKI
LVVQADVSEREDVSRLLEEVKNSM-PPLRGIVHAAGVLQDGMLLGQTWESFHRVMAPKVQGAWNLHTLTQNLELDFFVCFSSVSALLGSPGQGNYAAANH
FLDVLAHYRH-GLGLPALTVNWGPWAGGGMAVEEL-QTRLSRMGIEGLQPEQAIAALESLLAANVQTTVANVDWSLFKDLYEAQ--G----KRSLL----
---------ELLGEQPQEAQ----LPQ------------------QSAQPSEILQRLQAAA-PSERISLLIAYIQGEVAKVLRLESPDPQQGFFDMGMDS
LMAAEFKNRLEVNFLTSVPVTLMFDFPTIKDLAWYIGKE-----------
>tr|K9T4M8|K9T4M8_9CYAN Polyketide synthase family protein OS=Pleurocapsa sp. PCC 7327 GN=Ple7327_2136 PE=4 SV=1
DWLYEVVWQPSKRQKTGQKTAENWIIFADRQGIGVKLAKALEEGDRAILIFLGQSYAISDEGHYQIDPTQPDDFQRLFEQI-K---PCCKVVHLWGLEVT
TDL----Q--QAQVLGCGSVLHLVQALIKARQLPKLWLATRGTQPVIDSTPIQVQQSSLWGLGRVIRLEHPDLPCKCLDLDPSE---ESDDILTLLEELY
SPDAEDQIAYRQGIRYLPRLMQRTSQDYGKSQPFMIREDGSYLITGGLGALGLQVARWLVEQGAKHLVLVGRSQSSQ---AAQETISQLE----KAGARV
CVIQADISNPEDVARIIVFYQKQSKIQLRGIIHAAGILDDGVLLKQTWERFERVMAPKVQGAWNLHVATQDLPLDFFVCFSSIASLIGSPGQGNYAAANA
FMDALVHYRR-GMGLPALSVNWGVWADVGMAALSAQNQALEQQGLSAIALQPGLQLLKE-LLQQAT-------------QVGALPV-----NWSI---FL
KQLPETFFEAVTPKSE---------------------EKLVQ---PRSEFLQQLE----SAASSDRKTLLFDRVRSQVAKVLGFSLIEPQQNFGDLGMDS
LMAVELKNSLQTSLGISIPLTSAFDHPTIELLTNYLAQE-----------
>tr|A0A0A6P5Y7|A0A0A6P5Y7_9GAMM Uncharacterized protein OS=Candidatus Thiomargarita nelsonii GN=OT06_42525 PE=4 SV=1
DWLYTVAWQSKVE---PQAEPDSWLILADQGGVGAKIAELLQAGEHCVQLYAKTSV----------------DFEPILKTL-QTEPFSLGIIHLWSLDVA
GSEELLSAIEQAQRLGCESVLHLVQTLSRHEVSPRLWLVTQGAVPV--KSPLNVAQSPLWGLGKVIALEHPDWWGGMLDLAPEMP--LD-AAKSLLTEIQ
NSQGEDQVAFRNGQRYVARLVRYRRP-----QAMPLDADNTYLITGGLGALGLIFAQWMAARGAQHLALIGRSNASH----AREILDQLA----RNGTKV
RVFQADVSCQVEMAKVLESIKI-SMPPLRGIVHAAGILDDGVLVQQNWERFMRVMAPKVVGTWHLHTLTQDLPLDFFVCFSSSSTLMGATGQGNYVAANT
FMDALAHHRR-ARGLPSLSINWGVWADAGMAALGSYDQNFAEYGIGKIATKQGLQVFGE-LLEQAV-------------QVGVMQV-----NWSK---LL
QQFSPNLLSELVNQIHQVE---------------ETEQQPAR---QLEELRLQFK----KASPDERIARLTAYLQTQVANALRLNQLDVQQPLNNIGVDS
LMAVELRNKVRKELGVDVPIVK---FMEGASVVDLATQL-----------
>tr|B2J016|B2J016_NOSP7 Beta-ketoacyl synthase OS=Nostoc punctiforme (strain ATCC 29133 / PCC 73102) GN=Npun_F3360 PE=4 SV=1
NWLYQIAWQRQNLEPASNKQPSSWLIFADQGGLGQKLAQLLTAGDRCIMVSAGAVYQQLQADRYQINLAHPEDFGRLIQD--N---PCQGIVHLWSCDAT
T---------EPQLTSCGSVLFLLQAIYNAKALPSLYLVTKGTQTVGQLTPLQVQSATLWGLGRVIALEHPELHCVRLDINPDA---PEDHIPSVAQELL
VPSREDQIAYRQGLRYVARLVRSDVAEYGKPKETTIQADSSYLITGGLGALGLQVAQWLVEQGAQNLVLMGRRGVSP---ENQPAIEQLE----QAGARV
LVVTADVSQQEDVSQMLATL--ASMPPLRGIIHAAGLLADGMLLRQTWENFELVMAPKVAGAWNLHTLTKELDLDFFVCFSSVSALLGSPGQGNYAAANA
FMDALAHHRQ-ALGLPGSSINWGPWADAGMAALSSREQAWAAQGVQPIPLEPGLQILAK-VVQQLA-------------QVGVLPV-----DWSK---FT
AQFPSDFLAEFTNAIS---------------------KV-TP---QVAELRQQLE----AAAPKQRPILLMNYVRSQIAKVLNLTEIDPKEGFLQLGMDS
LMAVELRNRLQSSLGCSVPASLIFDYPTVDALVSYLIQE-----------
>tr|L8LKG2|L8LKG2_9CHRO Polyketide synthase family protein OS=Gloeocapsa sp. PCC 73106 GN=GLO73106DRAFT_00011610 PE=4 SV=1
ADLYEIVWQIQPQQTEKDSRIRNWLIFAETEEFAVPLANCLKKRMQVILVLAGENYAQK-EEHYLINPYKSQNWERLFREN-L---ENFGIIHLGG---S
PSF----CPEKNQKLGCGSVLHLMQGLNLYNQCQKLLLVTRNTQKVEDEPDLNPEQASLWGLARVIRLEYPDLACICLDLEPTN---LEKDLVILQKEIL
QNDLEDQIAYRDGDRYVPRLTKKQKPQYGK----MLSADASYLITGGWGALGLKIANWLVQKGAKSLILLGYSQPSA---EALAQIQTWQ----QSGVEV
KPLQANLGDRQAIEHLFRDY-----PQIRGIIHSAGTIEDAYLINQNWESFERVFASKIAGTWHLHQATEKLNLDFFVCFSSIVSLLGSQGQGNYVAANA
FMDALMHHRR-QLGLSGLSINWGPWSHQGMAALE--QKGFSQRGIATIPPDVGLAILEE-LLLRYT-------------QVAVFSV-----DWKQ---FF
LKSPPQFLSEFYAPTNLE-----------------KSS-----------------------TPVHNLESLKQYLQTQIAQVLGFSDIDPEQDFQEFGLDS
LMIVEFKTKLEKYLAITLENSIISQYSSVNLLADYLLKE-----------
>tr|A0A073C9W9|A0A073C9W9_PLAAG Pks5 OS=Planktothrix agardhii NIVA-CYA 126/8 GN=pks5 PE=4 SV=1
PDLYRLTWKSKPRLSAQTRKTASWLIVSDCPEFGVKLAKSLEEGDRCSIIHPENVSGKLQ--------------------------PCEQIIYLWSSDQT
FDE------------TGASLLDLVQRITQQPTPPRLWIVTYSSPLS------KQTKNYAFGLAKVIRLEHPNLASICINFESFNLISLNQNFQTLLEELE
NPDEENQIVYRQGVRYVPRLNAYQPDNLGK-QDITIREDSTYLITGGLGALGLQVAQWLVTKQAKNILLVGRSEPSQ---HAKNVIEKLK----NQGVTI
QVIKADITDLEAVEKVIKPYTINQLPPLRGIIHAAGVLNDGILEKQTWERFREVLAPKVTGTWNLHTATLNLPLDFFVCFSSITALIGSPGQSNYVVANS
IMDGLMEYRR-LLGLPGLSINWGAWDEAGMAALSNQNQGLLAQGMKAIAPQQGLKVLDQ-LLSEIP-------------QIGVFSV-----DWSA---FI
EQVPDGFLEDLISQDKAR-----------------KPEVNAN---QKLDFLQQLA----TASTSDRKTILSEKIRSELATVLGYSSINLEDNLSDLGMDS
LMAVEFKNRLQNCLGSTFSLSSVFDYPDLEALVDYFLTD-----------
>tr|A0A0A0WDX2|A0A0A0WDX2_9NOST PuwB OS=Cylindrospermum alatosporum CCALA 988 GN=puwB PE=4 SV=1
NWLYQVEWRQQVRFISAAAQPKHWLLLCDNHGLGEQLAAQLRQGEICTLVFPGELAEKLDEQTFAINPQQPEDFQQLLRDI-SHQPAIHGVVHCWSLDTV
GADVLSSDLQGASQQSCGSTLHLVQGLVKASLSPRLWLVTRGAQS-VGDAVSGVAQSAIWGLGKVIALEHPELKCVRVDLDPDV---LGDAAPALFAEVW
ADDAEDQVAFRNGLRYVARLIRSAQSQRGK-AELTLRGDRTYLITGGMGGLGLLIARWMVENGAKHLVLLGRSIPSK---SAIETLEVLQ----NKGAEV
MVVQADVTDVAQMTQVIAEIER-SHFPLSGVIHAVGVLDDGVLQQQTWERFARVMAPKVEGAWHLHQLTQNLPLDFFVLFSSVASLFGSPGQANHAAANG
FLDALAAYRQ-QQGLPGLSINWGVVADIGAAARQA--DGVKTKGMGTISPPQVLEILAQQLQTPAA-------------QVGVVPV-----DWSK---FI
AQSTPWFFSDFQQ---TDD----------------SQE-QPS---QNSELRQQLE----VIPKNEQRAYLTNYLCTQVAKVLGLNSIDIQQGFFDLGMDS
LTSVELRNRLQTSLGCSLPSTLTFKYPTVAALVDYLAVE-----------
>tr|L8M2H9|L8M2H9_9CYAN Polyketide synthase family protein OS=Xenococcus sp. PCC 7305 GN=Xen7305DRAFT_00038270 PE=4 SV=1
DWLYEVNWQPQNLDCKTNELPNNWLIFSQDGDMAWELEKQLP--GDSILVFPGAAFKAIAANQYQINPTQIEEFQRLWQEK-S---SDSQSWGIIYLDLG
ANG----R--SPLQHGCAAILHLMQSSATEQ-LSQLVIVTQDTQFKT-----KNLSGAIWGLARTINLEYPKLNCICLDLEAND---IEQNASLILEELQ
HGNLETQIAYHNHQRHIPRLVRQNN-EYGKRGWGEIRNDGCYLITGGLGSLGLQVATWLVAEGAKHLILIGRNQLSD---TARKTIAELE----ELEVTI
KLEFADICDSLQLEQII-----QVQLPLRGVIHAAGILDDGLLKSLSWERFQAVLEPKITGAWNLHLATVRLDLDWFVSFSSVVSVFGAVGQGNYAAANA
FMDNLMSYRR-NLGLPGLTINWSIWDDVGMASLTPQQQQLSQQGLTAIAPEQGLKVLKR-LLQQVT-------------QSIVFPV-----DWSA---FL
AQQPDNFFERFKTPTT---------------------TQEP----QATTFLQQLE----TTPESDRQQILQEHIREQIAKVLGFPEIDTQENFADLGMDS
LMAVEFKNNLQASFGDAISLTATFDYPNIELLTEYIEGE-----------
>tr|K9XRL8|K9XRL8_STAC7 6-deoxyerythronolide-B synthase, 8-amino-7-oxononanoate synthase OS=Stanieria cyanosphaera (strain ATCC 29371 / PCC 7437) GN=St
EHLYQLVWFPNSNHNIYQVCVDHWLIFADRYGVGEKLAEELEKDRSCLLVFPKALEDCVENFRYSLDRNSREDWQKLLKDV-Q---TNIGIVFLWSLDET
EDF----V--TTQQQGCGSVLYLIQSLLENKQVAKLLLVTQETQAVANQASLQVQHSSLWGLGRVINTEHPQLNCTLLDLDGFD---P---VTCVLSELN
SIQQEHQVAYRQGNRYVARLDRYKLLDYGKTALTQINDQGSYLITGGLGALGLQVARWLVDKGARNLILVGRSKPNS---EAKVIIQQLE----ETGAQI
EVIQADIANLEAVNRIVRA---SSSPLLKGIIHAAGIIDDGLLQQLSWERFAKVISPKIMGAWNLHLATQNLPLDFFVCFSSITSILGTFGQGNYAAANS
FMDALMHYRR-SFGLPGLSINWGLWDDLGMAALNAEVKAFSDEGLETIELNSGLELLEQ-LLLQHS-------------QLAVFPV-----DWSK---FL
SAKPENFFQLFKPKSE---------------------VKNQ----PISNLNPIF----------SNISAFQQHIQTQVAKVLGFSSVDVQENFADLGMDS
LMAVELKNQLQTSLKIDIPLTITFDYPTVEALANYLFEK-----------
>tr|F4PZ76|F4PZ76_DICFS Putative polyketide synthase OS=Dictyostelium fasciculatum (strain SH3) GN=pks29 PE=4 SV=1
-HIKQSFIQPKQSPNI--EPIDH-LLFITST-FTTKLIQQAGSMTKSIGLFSSDDL---------MNPD------LLLDSM-EKNDKKVTIIYLESMEEM
TID----SLTPKSTQY----LHLHLVIRQEQLPVKLIALRSGFFN---------------ECLTSIAREFGYKCGN-FEFGTMVMTT----LDQIL-SNY
SKLGELDYKLSTIQVMVERVLLSKNSKDGKRLSYNLDCQGTMLVTG-QSGISVECIYYCLAPKLTNIIVLSFSKPKFEMH-IIKTNY--------PHVKL
HYLQCDLGHYNSLKSSIQSLYQSRMEPVSVVIHCAVTYVS---EKISLGEHAVAMSAKAVGAWNLHNLFEELKLNHFHLFSSVGQYLV-RESTSYGVANL
FLDSLAMYRR-SIGLEATSVAWGSIGSTGRAVNQGSNAT-QGLGMSFLPLSCIYGVLRSSFANKTPI-----------TRIMCASF-----LTKR---FI
GSHQFLTFGHLLDEDLGV------------------T-AK-K-----------------KNNAQDGGNSIENMIIDHIAEALSIELLSPDTKLKDYGVDS
MVSIQIKTWLEQEFGKTQIHSQIS-NGSLNSIIQAVSNR-----------
>tr|F4QFA2|F4QFA2_DICFS Polyketide synthase OS=Dictyostelium fasciculatum (strain SH3) GN=DFA_11170 PE=4 SV=1
-FIKQSIYQPKNSPSN--ESFDH-LLFITSSSLLARLIEQSKQNNNNISLFSVDDI---------MDET------ILLDSF-NKDNTQVAIIYLESIEEM
KID----NLELKSMQL----IRLHQIIRKEQLPIKLITLIASQLN---------------HCLIPICREYQR--PSLFMFDSISITS----LSQIL-ANH
QHIGEKHVRLDTIQLSIERFVETPNAKDSKRLHYQLDVQDTLLITG-QTGVAVESLQYIISPRLRDIIVVSYSSPKYEIN-DIKTKY--------QHVQL
HYLQCDIGNYSQLASSIQQLYQSTIRPVKSVIHCANNYVFSLSDDLTLDVHHKALSAKAIGAWNLHNLFEELKLNHFHTMSSMAQFTG-RESFSYSVANS
FLDNLALHRR-SLGLSGTSIIWGSIGSTGRVAIKGSNEG-ELVGFNLLPLYTVYGILRASFINHTPF-----------TVLQCASL-----S-TK---FV
ASSPNLLFCLSSDVIPK-------------------R-ST-N-----------------IN-GSQQQDNIENKILEFIAETLSIELLNGDTKLKDYGVDS
MIAIQIRSWVESEFKKSNLQAQIS-NGTINSITETINRI-----------
>tr|F4Q303|F4Q303_DICFS Polyketide synthase OS=Dictyostelium fasciculatum (strain SH3) GN=DFA_08563 PE=4 SV=1
-FIKQSIYQPKNSPSP--NRYDH-LLFITSSSLLKRLIEQSKKIQNNICLFSVDDI---------MDES------TLLDSY-KD-GSKVVIIYLESVEEM
KID----NLELKSMQL----IRLHQIIRKEQLPITLISLISSQLN---------------QCLIPICREYER--PSLFLFDSVSMIS----LSQIL-ANH
QHIGEKHVKLNSIQLSTERFIETPNAKDSKRLNYSLDIQDTLLITG-QTGVAIESLQYIISPKLRDIIVVSYSAPKYEIN-DIKTKY--------KHLQL
HYLQCDIGNYNQLALSIQQLYQ-NIKPVKSVIHCANNYVFSLSDDLTMDVHHQALSAKAIGAWNLHTLFERLKLNHFHTMSSIAQFAG-RESFSYSVANA
FLDNLAQYRR-NLGLQGTSIIWGSIGSTGRVADKGSNEG-LSVGFDIMPLHSVYGILRACFINDTPF-----------TVLQCTSL-----SINK---FV
SASPNLLFCLMSNVIPK-------------------N-TI-H-----------------NNLSASLQDNIENKILEFISETLSIELLSGDTKLKDYGVDS
MISIQIRTWIENEFKKSNFQAQIS-NGTINSIIETINRN-----------
>tr|F4QC64|F4QC64_DICFS Fatty acid synthase OS=Dictyostelium fasciculatum (strain SH3) GN=DFA_11312 PE=4 SV=1
-FIKKSIYQPKNSPSP--DNIDK-ILFITSTSTSTRLISQASSISKQVKSISSDDI---------SDES------SLLDSY-QQ-GEKVVIIYLESLVEM
NSS----NLDKKSMQL----IRLHQILRKEQLPVKLITLITGQLN---------------QCLVPICRDYDR--PSMFSFDSISISS----LNQIM-ANS
NHIGEKNIKLQVIQVNVERIIDAPKAKDSKRVHYQLDVQDTLLMTG-QTGVAVESLHYIIAPQLRDIIVVSYSSPKYEIN-HINKHQ--------AHLRL
HYVQCDIGNYDQLSSSIQQLYKSTIKPVKSVIHCANTYVFADADDVTIENHRQAMMAKAIGALNLHNLFEKLKLNHFHLLSSIAQYSG-RESFSYAVANS
FLDHLAQHRR-NCGLAATAIIWGSIGSTGRVASKLSNEA-SSIGAHMMPLSTVYGVLRSSFIDSTPF-----------TSIICAAI-----KVDR---FL
SETPNLLFCHLSSIVAK-------------------K-SN-N-----------------N----DNQDNMNDKIIEFIADLLSIELLNGDTKLKDYGVDS
MNAIQIKSWIEVEFKQSNIQAQIS-NGTINSIIENVNRI-----------
>tr|F4Q8K0|F4Q8K0_DICFS Putative polyketide synthase OS=Dictyostelium fasciculatum (strain SH3) GN=pks30 PE=4 SV=1
-QIKESVTQPKNSPSL--EKIDH-ILFITSSSLSTKLIQQANLITLDISFFSSNDI---------MDDN------QLIDAY-CSSNKKVVILDISTLDPM
NVD----NLVSKSMEY----LRLQQIIRREKLQIKLISLRTSTLN---------------DCLSPISREFNFKSGSLFSFESLALSS----IKQIL-SNY
QALGEGEFKLEMVQVNVERLVYARDVKDSKRHSYELDVQGTLMMTG-QTGVAAECLYYLIAPKLSNIIIVTHSKPKFEMH-TIQSQN--------PHLTL
HFIQCNISNYDQLRLSVKQLYETTIEPVKVLLHCANQYMATTADDITLEDHQQALSAKAIGAWNLHHLFEELKLNHFHLFSSMAQYLV-KGNTSYGVGNA
FLDGLARHRR-ECGLEGTAIAWGSIGSAGQVAHQGSNAS-SSNGLILLPLSYVYGVLRSSFINQTQL-----------TRTICGNV-----SLKK---FV
ESLPFLSLTQYLT---I-------------------S-NK-K-----------------SMMGGVDTNSNENKIINHIAETLSIELLSPDTKLKDYGVDS
MVSIQLKTWIDQEFGKTQIHSQIS-NGSINSIIETIQRS-----------
>tr|F4Q2B0|F4Q2B0_DICFS Putative polyketide synthase OS=Dictyostelium fasciculatum (strain SH3) GN=pks39 PE=4 SV=1
DIIKQSIFQPKNSPLL--GEYDH-LLFITSSSLSDRIIKQSTLVSNSVGVFSSDDI---------MNES------SLLDAL-NNNSGKVVIIYLESTEEM
KAN----NLELKSIQL----VRLYQIIGKEQLSVKLITLISGQLN---------------QCLVPIRREYDR--LYTHQIDSVTICS----LAQIL-SNN
HYTGEEEFKLGKIQVLVERLVHGSDQKDSKRLDYHLDVQDTLLITG-QTGIAVESLYYIISPKLRDIIVVSFSSPKYEIN-HFNKSNNNNN---NTQPNI
HYIKCDVGDYSQLKSLILDLYKQTIKPVKTVIHCANIYQTVRAEDINIESHHQAMSGKATGAFNLHNLFEELKLNHFHLLSSFAQYIP-TNGLSYSIGNA
FLDGLARYRR-ERGLEATSIAWGSIGQAGKVAEKVVDLT-NSFGFTMIPLSYMYGVLRSSFINQTPF-----------TNLLCVDI-----VTKK---LV
TNQPNLINCHFLDIGAN-------------------I-KN-D-----------------S--TLSNTDSIEIKILDYVSEILSIELLSGDTKLKDYGVDS
MVSIQIKSWIETEFKSC-SQSQIA-HGTINSIIETIKRN-----------
>tr|F4QC62|F4QC62_DICFS Putative uncharacterized protein OS=Dictyostelium fasciculatum (strain SH3) GN=DFA_11310 PE=4 SV=1
-YIYKTELQPKNSPSLINNQLDS-IIFITSSSIQQRLIEQANNMRENVTLFSSDNL---------INDDDNN---LLLES---Q--KRSLIIYLESLEEM
TSD----NLVVKTMQH----LKIHQIIRKAQIEVRMLTLIDSPLN---------------ECLIPNCREYQDQGSVLFEFDSIPISN----LDQLL-SNS
SLLGDKEFTLKDLQVMVEREFKSPLSKDYKRVNYTLEIQDTLLITG-QTGMSVECLQYVISPQLRDIIVLSFSAPKYEIN-QTKMKNH-DG---SSTLAI
HYIKCDVGNYSALESSIVELYKTAIKPVKTVIHTANFYHVLGADSINLENHNEAMSAKAVGAYNLHNLFVKLQLCHFQMLSSVATLIS-KGNTSYGVGNA
FLDGLAKHRR-QCGLAATSINWGSIGSTGKVSDKGARTN-GSLGLSMLPLSVVYGVLRSSFISQTPF-----------TQLRCFDA-----NLKH---FV
SAIPYLRFTPLVTFDSTS------------------A-TK-Q-----------------NNQGVGGNDTIESMVIDQISDILSIQLINTDTKLKEYGVDS
MVAIQIKSWIEGQFNKLNLQSQIS-NSSINMIIDLIKK------------
>tr|T2LFB8|T2LFB8_9GAMM Beta-ketoacyl synthase-like protein OS=Halomonas sp. A3H3 GN=HALA3H3_970020 PE=4 SV=1
HFSYLVELTPAPLHAETAQ--RRHLVV-ASEALAANLVEALQSGAS-----------ALL-----VSQSAPAELLPALAQM-AQAELTLNVVDLRGLG--
---A---NSTEAQTARCN--HALQWTLALEQLAASLWLVTNGVSDLPASATDAPGDAVLWGFGRSLANEAVGHSVYLLDIPAAV---SEPALHAWATLLT
QPDSENEALIDNQGHRFATRLRTLPAMPGKTAAMQLSADASYLVTGGLGGFGLRTAQWLVEKGARQLILLSRSGPTSE--EAQAAIASFE----QQGVTI
LAAACDITDRTALADVLERAKG-ELAPLRGIVHAATVIDDGLIRNLDAERIQKVLAPKIDGARHLDALTREAELEFFVLYSSATTLFGNPGQANYVAANH
WLEAFAANRR-AAGLPATCVRWGAIEDVGFLANTRTRDAQERLGGSALRSDDALKVLEQ-MLLAGP-------------SLGVLEL-----EWGA---LA
RFLPTARFNEIARASDDD------------------G--SAD---ADDDISALLA----DLSPEELHSTVTDLLRAELASILLIDKLDIHRSVYDMGFDS
LMGVELMTAIENRLGVQVSVMVLSEASTLDKLAGVLIQK-----------
>tr|A0A0B2B9T1|A0A0B2B9T1_9ACTN Beta-ketoacyl synthase OS=Mumia flava GN=LK11_42005 PE=4 SV=1
RFVYRLEEVPLPGDVNTLARSEQWLVMHAAGSFGGRLADALARGYPADIVDVTHAADAIA-----LPAGQPAHVV--FCAT-PLAG--------------
---D---DLMAAQRNGVIALAELVRALGMQ-AATRLTVVTRGGA--AGAANAHPEQATLWGLGRVLANEHPELACRLIDVDRAA---DRIP-DALIRELT
GAAIEEEVVLGVHGRQVPRMLT----APGKAGSLALDPHGTYLVVGGTGGLGFASARWMVERGARRLTLASRSGELAA--AAREEVERWRA---TLGVTV
DVVSCDVTDAAAVDAMIEAIVR-RGGPLKGVLHSAMSIDDGLVRNLDDARMAAVLAPKVAGAWNLHRATRALPLDLFVVYSSATTYLGNPGQSNYVAANT
FLEALVEHRR-AAGLPGTFMAWGPLEDVGFLAHADTREAQSRIGGASITSDEAMVALER-VLVAAA-------------GEAVVRL-----DWHA---VA
RGMPAARYSLLQSHAKGG------------------D--ARD---GGTQLREEVL----ALPRDEAIALVARTLQGQIARILHMTRIALDKSVLDMGMDS
LMGMELGLAVEEAFEVKLSVMAIAEGASVTTLAGRIVDS-----------
>tr|Q4C7P4|Q4C7P4_CROWT Beta-ketoacyl synthase:Acyl transferase region:Zinc-containing alcohol dehydrogenase superfamily:Phosphopantetheine-binding OS=
NWLYGVKWNKQPLTANINTEAKNWLILGDRQGIASHLVQTLESGENCIVAYSDSHYQQIGAKDYQVNPQNEQDISRLLEKK-Q----FDQIIYLWGLDDP
SEEDLIDTLETGSENHCRSILQLIQNSY--NKPPRFWLVTKGVMATKNDPVVSITQSSLWGLGKAISLEHPEFNSVCVDLEINTE--LKQQVKVLLEEIN
ANSPENQIAFSKNTRHVARLVPQKLSQRGKQSSLKFSEDGTYLITGGLGDLGLLVAQWMIEKGAKNIVLMGRNEPKL---EQKQKIKALE----TLGGNI
TIAQGDVSNKEQLATILKAISPSPLSPLKGIIHAAGVLDDGVLKQLTWERFNKVMSPKVQGAWNLHNLTKDKPLDFFVLFSSAASLLGSPGQANHVTANT
FLDTLAHYRR-SQGLPALSINWGLWSDIGAAARQV-----KRQGVGAIAPDEGITILEM-LMKDLA-------------QVGVVPI-----KWDE---FL
QIEQNIFFSNFKQ---QKA----------------TST---N---SSSNFLQQLE----DIPPEEKENYLREHIRAEISQVLGFNDVDMEIGFFDLGMDS
LTAMEFKNRLQNTFACTFPSTIAFDYPTGDALVSYIATE-----------
>tr|A9AUI9|A9AUI9_HERA2 Beta-ketoacyl synthase OS=Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785) GN=Haur_1873 PE=4 SV=1
DLFYSVKWLPDQASQPPHQALGSWLILGDQQGLGQELAQLFQAGESSVLVTPADNYEQLDEHHFQLNPRELSQFQQVLQAN-L---PYRGVIHLWGLDAV
DTEELLTTLSEAQGLGCDAAVQLIQAVVELDELPRIWLVTRGAQSVPEQATIAVAQAPLWGLGRVLATEHPELMGALIDLDPTK---SSNEAFELFQAIT
TGIDGEQLALRQNQRYLARLMRDSFD----KQGLGLRPDASYLITGGLSGIGLEVARWMLQQGARRLILLGRTTIPDRSASRIAAIKELE----NLGASI
HVASIDVSDEEQLAMFLAEYQQQGWPPIRGVIHSAGLIKDQLLMRMDQETFDVVNRPKIFGSWLLHRLLRKSPLDFMIMFSSATSIMGMFGQANYAAGNA
FVDALAHFRR-SQGLPAMSINWGLWAETGIVALKM--NDLNQSGVIGMTSEQGLEVMAQ-LFQRPI-------------QIAPMLT-----DWQR---WQ
QAYPQTFFKSHFELVNAQIA-------------RQTDQVAVP---SQSGIVQELL----LLEPEQRQTRLEMHLRDVIATVLRLDRIDLDQPLNRLGLDS
IMAVELKNRIEVDLGVSLSIVELLQGASIAQLTQRILPS-----------
>tr|B1WWV7|B1WWV7_CYAA5 Polyketide synthase OS=Cyanothece sp. (strain ATCC 51142) GN=cce_3078 PE=4 SV=1
NWFYRVKWQKQPLFSNIDADGKNWLILGDRQGIASQLVQILESGKNCIIAYAEKTYQQLGQQDYQINPQRPQDWQRLLSKQ-S----FEHIIYLWGLDTP
SEEDLLETLETISENHCLSILHLIQHSY--TNPPRLWLVTKGTIATDDDLISGIAQSSLWGLGKAIALEHPEFNCVCLDLDANTP--LKQQIKLLLDEIS
SNSPENQIAFRKGTRHVARLVPQKLPQRGKASTLKFREDGTYLITGGLGGLGLLVAQWMVEKGARNLVLMGRNQPNT---TQKQKIQALK----ALGANI
IVAQGDVSNQEQLEAILQNIETASSAPLKGIIHAAGVLDDGVLKQLTWERFNKVMSPKVQGAWNLHTLSQDKPLDFFVLFSSAASLLGSPGQANHVTANT
FLDTLAHYRR-SQGLPALSMNWGVWSDIGAAARQV-----NRQGVGAIAPSQGIASLEQ-LMKDMT-------------QVGVVPI-----NWNK---FL
QFNPNIFFANFKP---KKA----------------KLA---E---NKNNFLQQLQ----TIPPEDKRDSLKDYIRSEVAQVLGFNDINMETGFFDLGMDS
LTSMEFKNRLQNSFGCTLPSTLAFDYPTGEALVNYLATE-----------
>tr|B4WGT1|B4WGT1_9SYNE KR domain family OS=Synechococcus sp. PCC 7335 GN=S7335_1374 PE=4 SV=1
RWLHELVWQVKTHDQPSNQNAKFWLLFSDRQGVGKQVAKELRNSDRVIEVMLADTYQLDLTDTCRLNSLDPAAFGQLFDDV-PTLVLACQIVYLWALDAN
RII----GDLLDQERICGGLLHLVQTLAKFP-KVRLWLLTQNAQSIA-PSPLDLQQSPLPGLARTLRLEQPELGCTSIDLPQPF---TDRAQDLLVQDLC
APGPEEQIAYRQDNRFVARILPQNKASYGKPHQPLINPQATYLITGGLGALGLKLARWLAEQGARHLVLMGRRSPSE---SARQAINELQ----RSGIAV
ETIQADVSNLSALESALSPYLTLLKGPLKGIFHLAGTLEDSLLINQSWQNFAKVMKPKVMGAWNLHTLTKSIDLDHFVCFSSIVSVMGSLGQSNYAAANA
FLDSLAHHRQ-SLGLPALSLNWGPWAEAGMVALDERSKKMVEQGLTQILPEVGLDLMSQ-LMQQKA-------------QIGIIPI-----DWAT---FM
ATASGQLLSAVKPVTA---------------------PQPR----IQSGVLSQLAKCSPEERLRQRAQILTGYLRTQLAKVMGFSAIAPDQQFGDLGMDS
LMAVEFSNRLQKNLNHPIPQTLAFDYPTIDALANYLSHE-----------
>tr|A0A0P8A0W8|A0A0P8A0W8_9CYAN Polyketide synthase module OS=Phormidesmis priestleyi Ana GN=HLUCCA11_05235 PE=4 SV=1
QWLHEIVWRSHPLPQTHKLAQKRWGLCGEVLGVSSI-VALLQEGQPFEALYQA------------------------------EDQVFDGVVYTLPTRPL
PTDVTDIALVTATETICRQALETIQMLAKQPNSPRLYFVSTDVTP-----ETQLVHAGLWGLLHTAQLEHPGLRCTYIQAETP---------EQIVAELL
SDSVETQVIYRDRTRHVARIENYPEESTGKPSAVKFHTDASYLITGGLGGLGLVMAEWMAKQGARRVILLGRQAPDS---TAQIVIDRLI----NNGISV
EVMSADVADSIAMATALDRINQATDHPLRGVIHAAGVLDDGLIQQLTWENFEPVFAAKATGAWNLHTLTQNNELDFFILFSSAAALFGSPGQANHAAANA
FLDGLAHYRN-QVGLPALSINWGAWSTVGSALYQQQ-GIEHFPGIETIDPKSGIAQLEK-IWSTTP-------------QVGIVPI-----DWQV---FL
TQNNLQFQTQAQTHAQTHAQTHAQTH-GLMAERNRGVTSPSS---ISSSLLIDLT----HATPEQKRERLDLYLCNQICKTLGFSELDRQTGFFDLGMDS
LTALELKNSLQTDLGLVLPSTLAFDYPTVEALLDYLAAQ-----------
>tr|W4BAS5|W4BAS5_9BACL Beta-ketoacyl synthase family protein,phosphopantetheine-containing protein OS=Paenibacillus sp. FSL R5-192 GN=C161_02745 PE=4 
RLFLETVWRA--------------------------GVSAFGIGTNCHVILEEPPVT--------IPVSAPVTARRLVAD---------YVRLLERNEQY
---ALDICSTASTGRG----HYP----------FRLSLMGRDTE----------------GLLNTLRQ---LENKPFQSIAQLGVEGLSQLMRSAI----
QDGRESEYLL----KQIAHLYVQGADAYPMERPIHMREGGVYLITGGTGGIGMETASALSAPEKIKLVLMNRSPFPERATAQIQRIKEME----AQGTEV
HLYSVDIADPIQLASVLSKIRQ-QHGLVSGIIHGAGVAGEGFLMNKDREAFERVMRPKVLGTWSLDQLTRADQPDFFVMFSTATTFFSEPGQGDYTAANA
YMDSFAAHRR-QAGLSTLAVNWTAWKETGMARFHAN----SDGGFKAITTARGIQGLQEAMRKDIT-------------QVLIGEL-----NRGI---YQ
DDMPLMLFSSDISEAIET------------------GRKGDSS--RSHESSGEM-K--LLGRMDEVYSVIESALGRLWSKSLGVNELSIYDDFYELGGDS
ILGLKIANGLTKELSILVNTAEILMYPTIAESAAYLEES-----------
>tr|A0A0J1EY51|A0A0J1EY51_9BACL Uncharacterized protein OS=Paenibacillus sp. VT-400 GN=EL84_29065 PE=4 SV=1
RLFLEAAWTA--------------------------GISAFGIGTNCHVILEEAPVQ--------TFVQA-EERRRLIAA---------YHDYLDSYDEL
---DLSLCGTAAQGRG----HYK----------LRIAIPFKDKE----------------ELVSRLDK---LRGCPFSEIKPPVAYELNEQADRVL----
NEHGWEDQHL----EEISILYTQGADTYPLLSEVTIKEQGVYLITGGMGGIGRAFTEHFANRHNVTLILAGRSDFPDRECNKIKWIHSIE----TKGSTV
GLYSVDTGDLQQVSRLMENIRE-QYGKVDGIVHGAGVAGEGFLASKDAETFNRVLLPKVQGTWNMDQATAQDSLDFLVLFSTTSTLFSSPGQGDYSAANS
YLDAYAAYRN-RRGGRTLTINWVAWKETGMAKFGVN----DDMVFKSVLTKSALKAFDQAFQRKVH-------------RSIIGEL-----NYSE---YM
GDMPMMMSEEVYNTIQDQS---------------ASVIAEVEM--RKATLNKEV-S--LHGRNDGQYTAMEQMLSRIWSLHLGLTEMDLYDDFYEYGGDS
IIGLKMASDIYRETGIQVNPSDVLQYPTIWGLGVHLQSL-----------
>tr|A0A0G2IGJ5|A0A0G2IGJ5_9PEZI Putative lovastatin nonaketide synthase OS=Diaporthe ampelina GN=UCDDA912_g00221 PE=4 SV=1
EICFNLEWKPDVDILEDDAISRVFIAHTADAAVAAAVASAVGGTRHAVSVVRFADLA----------------QH-RLKN--TC-----CIVAMETTAPF
LAS----SF---SEAE----FGLLRQLLT--TAGGLLWLTLDPHE-------DPRMALIAGLLRTVRWERDLDGSDLLHLP--CAELV---ASSVVGVSL
SPDRHADYLVDGGFVQTARIVAAPAVGPGKPAPTRLRPDATYLLPGGAGGLGRSIARWMAAQGARNLVFLSRGGDGAA--TTRELLAELG----AAGVRA
AALRCDVGDEAQLVAALGEAARLGFPRVAGVVQGAMQLRDSAFEFMSHAQWEECLGPKVQGTWNLHRHLP-ADMDFFVMLGSVAGLVGNRGQSNYAAGNT
FQDALAVHRR-ARGLAATCIDLCNIMSVGFVANQETLNKLFFFAHDGISEDEFLSLVEFHLDAAAGGEG-------LAPQVGVGLA-----PLSV---FK
LPEPTFLFRQLRSAGGEAGG--------------AADGAPDQD-GAAVSVTNALKF--A-ESPEAAAELICGALVRRLSRTMRIPDVDVGKPIHVYGVDS
LVAMEIRNYLASECGSEVSVLEIMGNKSIEALSG---DI-----------
>tr|G7XBG1|G7XBG1_ASPKW Fatty acid synthase S-acetyltransferase OS=Aspergillus kawachii (strain NBRC 4308) GN=AKAW_02699 PE=4 SV=1
KLATHLQWKPDIRFMS--------LLCTSYQTWMQSLAVCLSSG---------YDVH----------------WC-TFEE---DLPTE-NVIAVLDFDRP
FLY----DI---SQAT----YTKIQSWLA--SVKRLLWVTHSMQIE----CKDPRYCLILGLTRTLRYELNVDVG-TCEIDLFEEAP------VVMGG--
QTIRDFEFILHRGVGHTGRAAITKVTTIGKQAGFSFSSTSSYMLVGGLRGIGRAVVRWMVEHEARNFTFLSRSAGNHE--EDQQFAKELE----SQGCRV
VMVAGSVTDPDTVQRT----IQQAERPVA---------GDQLFDKMSYEEWTTSLATKVQGTWNLHNALQDHSVDFFIVFSSAVSMIGNSGQANYAAANS
FLDGFVQYRR-GLGLPASLVSLGPVDEMGLMSQPELLSKQLSH--HMMGEGDVLKAFQLALLSADGLSSR------RPAVVVAGLS-----P-AV---V-
TSDPWLRFSSLPKG-TDMSN--------------AGGVDDEQ---LQRKFASARDDP-TSLIDGSCEALIIEKLGK-QIAMHNGLEEMGVDQYSSLEVDS
LMSLQIKHWLGRKVEVEVSLGDIMKARTVGNIAKLVTEY-----------
>tr|A0A0F4YNJ2|A0A0F4YNJ2_TALEM Lovastatin nonaketide synthase OS=Rasamsonia emersonii CBS 393.64 GN=T310_6161 PE=4 SV=1
KFCHTVEWKPDVDLLK----------------------------------------S----------------NR-DLRN--THCV------SLMELERS
VLA----DP---TEEE----FANIRHLLS--TCDGLLWVTGDFTS-------NPELNMIAGLIRAVRWERDLEGPNTLAISDPRPSIM---VQAILKSNT
DKD-NGEYVFQDGVFFTNRLVDATEMAPGKPVQMKFEEKASYVLAGGFGGIGRSIARWMASRGAKNLIFLSRSGAASS--AAQETIQELE----SRGVTV
RVFSCDVSDKDRLVAVLEE-CKTSLPPIRGCIQGSMVLADKIFENMSYEKFRAATRPKVQGSWNLHACLP-RDMDFFILLSSATGLVGNRGQANYAAGNT
YQDALAAHRV-SLGLHATSLDLGTLLSIGYVANRQLLGHYVASLLGSVREEEIHSVIEYCVKPT-GPSK-------RPIQIASSVT-----TAAE---YR
MPTPSWLFTQLASTSSSATT--------------GPGGEESA---SGLNIASLLES--A-TSLADAAAVVADAIRTKLSKLLNISNIDPSKSVSSNGVES
LVAVEFRTWLAKVLAADIPLLDILGTMPITEL---SVKV-----------
>tr|C4JHF4|C4JHF4_UNCRE Putative uncharacterized protein OS=Uncinocarpus reesii (strain UAMH 1704) GN=UREG_01317 PE=4 SV=1
--------------------------------------------------------D----------------NE-DIRR--PQSNTDYYIRRVSVRFPS
VLS----NP---TEEE----FDNIRHLLA--TCKGSLWVTGDITA-------SPEFNMIAGLIRSLRWERDLESPNTLSISNPQPAVL---LQAILTQRE
DKD-NAEYLLKDGVILTNRLVDAPEMAPGKLAPVRLREHASYVLSGGLGGVGRSVALWMASKGAKSLIFLSRSGSASP--AAQEVIRELH----SRGATA
HIFSCDVSDKAGLEAVLNQ-CKAELPPIKGCIQGAMVLADKMFENMTHDEFQMARKPKVQGSWNLHVCLP-KDMDFFIMLSSAAGLVGNRGQANYTAGNT
YQDALAAHRV-ALGLPAVSLDLGALLSIGYIANRQRLGKYIASLMGTTREEEIHGMIEYYITPK-GSST-------RPAQVASTLT-----TAAQ---YA
MPVPSWLFTQLSSTSSAATD--------------TMGNDKTD---SGINVTSKLAS--V-TSISEASDIIADAIRSKLSKLLSIPNIDTAKSVSSNGIDS
LVAMEFRTWLAKILGADVPLLDILGTMPVAGAGSLSTKV-----------
>tr|E4V736|E4V736_ARTGP Fatty acid synthase S-acetyltransferase OS=Arthroderma gypseum (strain ATCC MYA-4604 / CBS 118893) GN=MGYG_08825 PE=4 SV=1
RLVSRCQWKPDIDFLP--------LLHH-VHRWAYTVESHLTEG---------YAVH----------------WC-TLDQ---VPAGQ-VIISLLDLETP
FFD----NI---SEED----FHTFQTCISTKGDCRIIWVTHGSQLE----CADPRYGQVLGLARTLRFELDVDFS-TFEIDKFDANI------SLCKH--
WLDPEYEFLLQDGIIHVGRFHWTPLDTYGKKKPIILSPNGSYLLVGGLGGLGRAITTWMIERGARHFIFLSRSAGESD--SDKAFLQEVA----AQECTA
TIVKGSVADLDDVKQA----STVSLKPIIGIIHMAMVLRDQTFEKMTYDNWNTPLASKVQGTWNLHNVFKDAPLDFFILFSSVVALGGNTGQANYTTANA
FLDTFVRYRK-SMNLPAWAINIGFMQGIGYASNSKLVDKANSI--QMVDESYLFDALQAAMSKSGAGSGQ------FAIGLGTSKP-----P-SD---F-
KAQPLWRFTMYQNLQTRVDK--------------PGTITAAD---LKDLIEDVKKDP-TILDTPETEEKIAKELRI-LIGSRVGHEDRDKQEIDNMAIDS
LMTIEIRSWFRRNLSLDIPLMEISNAKTVGGLTATTLNA-----------
>tr|C5FXC7|C5FXC7_ARTOC Fum1p OS=Arthroderma otae (strain ATCC MYA-4605 / CBS 113480) GN=MCYG_07786 PE=4 SV=1
RLVSRCQWKQDIDFVP--------LLHH-PHHWGHMVESFLSEG---------YAVH----------------WC-ILDQ---VPANK-TVISLLDLDGP
FFD----NI---SEED----FRAFQTCMSTRSNCRILWVTRGSQLE----CADPRYGLVLGLARTLRFEMDVDFS-TIEVDRFDKNI------SLCKH--
WLDPEYEFFLQNDIVHIGRFYWTPLNTYGKQT-INLSPHGSYLLVGGLGGLGRAVTTWMVEKGARHFIFLSRSAGESD--SDKAFLHELA----AQECTA
TVVKGSVADFGDVKQA----ATVGLKPVVGIIHMAMALRDQAFEKMTYDSWHTTLAPKVQGTWNLHNVFKDVPLDFFILFSSVVALGGNTGQASYTAANA
FLDTFVRYRQ-SMNLPAWAVNIGFMQGIGYASNLKLVDTANSI--EMVDESYLLDALQVAMSNSGAGSGQ------FAIGLGTSKP-----L-SD---A-
KTQPLWRFTVYENIQKQVEK--------------IGTISGAD---LKSLVEEVEKDP-SILDTQDTEEKIAKELRV-LIGSRAGLENADKKEIDNMAIDS
LMTIEIRSWFRRNLSLEIPLMEISNAKTVGGLTTTTLNA-----------
>tr|L7HPL4|L7HPL4_MAGOY Fatty acid synthase S-acetyltransferase OS=Magnaporthe oryzae (strain Y34) GN=OOU_Y34scaffold01019g2 PE=4 SV=1
AGCFGQNWHEDVDLLS-----DEFVVTPASQKLAQAIVDTIKSGK------KCTSLA----------------WE-DVT----KEQGQYCICL-AEWESP
ILV----DL---TDEN----WTRLRDVVL--GSAGTLWVTGGAAMD----TPEPLKSLMVGLARAIRNENA--GVLTLDLET--AADMRQGCDAVLGE--
--TPDGEFAARRGRVFVPRVERLPGVTPGKPKV-PIVADATYVV-AGLGGICREIGRWLAEKGAKHLVFLSRTAASSA--ENKEFSAGLEK---TYGAKI
HAFDCDVGDKTALAGVLEA--IGHLPKVCGCVTGAMVLHDTLFDSMTADHVRTTVGPKVHGTWNLHEQLP-ADMDFFVMLSSLAGVMGHRGQGNYGCGNI
FQDYVAAHRR-GLGRRATTVDIGYLLSVGFVAHDEYVDHAMGL--KVMRSSDLHGLLATAMEAD--LDA-------SPAQVMCGLP------------YR
DDAWYWRFAALRNVGAA-------------------G-AAAGS-GGGISLREELARC-GPGDDEAAVDLITRALVQRLAKLMMMPDIDAGRPLSAYGVDS
LVAVEVRNWVSKEVVVEVSVFDLMANVPMRVLAA---NL-----------
>tr|J8FU51|J8FU51_BACCE Amino acid adenylation domain-containing protein OS=Bacillus cereus VD014 GN=IIA_05720 PE=4 SV=1
DWFYLPSWERKTLKSIKKEQKYKWLIFNDHLNRFNRLIEKLKREGDVIEVKTGGVFSEKSDGLYTICPSQKMHYEMLFSELEQKDLLPNKIIHAWSFNPV
NEVIDQERIERSMDEGYYSLLYIAQAIGKYEGALQLNIFTDRMFEVTGELNLKPEQATILGFSKICNLEFQNIKCRTIDMDTD---SQQMFEEAGLMESF
VDSTDIVVAYRGRHRWAQTIIQSPFEEEDVE-IDRLREGGVYLITGGLGGIGFEIAKDLANVPNVKLILIGRSEFPRNQWEQYEVISDLLT-MESQGAEY
MILSSDVSNQDDMKQAIEKAKSRFGS-INGVIHAAGVADYLGIMNREKESNNKILAPKIKGTLVLDALLKDEPIDFFVLCSSIGNVAYHMKFSGYNAANE
FLDAFAFYKRAHDGVFTVAINWPDWQEVGMSLKSAE------------IWAKQFNMDMESVL------HDGVT---------VEE---------------
-------GLKVFRSIINRNQQQVVVSIDLHWKLL----------NGANYYNELLEKGSKSTTYRPPTNEIEQQLYELLKDMFGIEEIGIYDNFFDLGMSS
LDLVRINVKLKEAFKRDLPIVVLYEHTSIKSLAKYLSN------------
>tr|A0A0F4QHA7|A0A0F4QHA7_9GAMM Uncharacterized protein OS=Pseudoalteromonas rubra GN=TW77_18075 PE=4 SV=1
DYLYEPVWMAKFIDEEESRNPKSAVIFVDKHGLYKGVVEKLKSNSRVYTVSLLEGGGEDDCVDYFIEKNEFASYSKVLGDIKKKEPGLDLIIHAFNVQA-
-DSDDIHNQDDYFELGAYSLLYLAQGLHESDQECVLKVLGTNTLNVGQ--SVNPFKQALTASVRVIENELPFISSQLIDVSEV---IQQQLPNSCMQTIL
GEVEHQVVAIKNGVPWYRQYQKVSVTLADPS-KLPVKANNVYLITGGSGGIGLEVANFLSEHSSVEIVLVSRTPIERASWNSIDVVEKIKA-VESKGSRV
HTYTADISDCEQFTQTYQAIVKEVGK-PNGIFHTAGVPGGRLLSLLSKQDAQKVFAPKVAGSLNILKTIDLEYVDFVINFSSISAL--NGSIFDYATANA
FQDGLSNINALC-QQKVKTINWDTWKEVGMAVKSVA------------P--KGYQTLLEQQL------KSGLE---------NNE---------------
-------GLKALSFALSCNKRHLVVSSSPHFDIP----------FD----LELIKDAGLDSNHDRTITATEQSMKNLWKDILGVEVMSRSDDFFELGGDS
LSLSKLLAHINHQWQLNLSLKQAFEKTDFHSMLRLVEG------------
>tr|A0A0Q4QFQ0|A0A0Q4QFQ0_9BACL Uncharacterized protein OS=Paenibacillus sp. Leaf72 GN=ASF12_16675 PE=4 SV=1
TLHYAMQWRKCSRSPEPSGIDGAAVVFMDRAGVGQTAASLRESGRLVIEVEDDGPCTANSNEGYQID-GSKASYLQLMQALKD--VPFGQIIHLLALDAH
DVSDSLETLKRRQASGAYSLFYLTKALVQAEIQQPLALHILNAVEATGAELLIPDHAPVYGMGKVMAKELSNVSCKYMDIEESVPL------GQIIGELQ
-ANDVYGVALRNGDRYTEIFAEVQLETSR---RLELQEQGIYLITGGLGGIGLEVAKWFAAQSKVNLALISRTPLPPSSEEASDKLRIV-KELERLGATV
ECISADAADYSAMEKVIADLKSKYGQ-IRGIVHGAGVSNDGPLADRGDDMFNAIYAPKVYGTWVLDALTKDQKLDFFIMFSSVATIFSAFGQGDYAAANA
YLDAYAPYRQ-RRGGRTLTVNWTTWKETGMAFDG---------GHVFDTIFRTLPTELALEGFA-SLLQSGAS--RALIGQIHYDGAGA-----------
-----MLLERSGVSCSDSIRKRIAAKKDSKRKQDGNVQKKERSAEGVVMLGR-------E---AGSYSELEQKLALCCKLVLGYEEIDIYDNFFEMGADS
LVLMKLQGEIETHTFEMVTISDLFEYSTVVQLAEHLQKQ-----------
>tr|S9TCG8|S9TCG8_PAEAL Amino acid adenylation protein OS=Paenibacillus alvei A6-6i-x GN=PAAL66ix_04999 PE=4 SV=1
NRFYRMEWRKENNQPEAWLSTGTALVFMDNSGRGKAIEAFHSRRRKTIIVD---ECKRIDATRFTID-GTRESYCELMRNLED--VDISQIVHLWTLNYT
GMASQVDEIRESQKLGMHSLYYLTKAIANANISNEIDWVTVYYTEVTGDERLIPENAPAYGIGKVITKEHPNVKCRYIDIEESTTD------SVVIREVA
AVSGHYIVALRNGERYTEVFTERELER-R---TAGIREEGTYLITGGLGGIGLEVAKYLAAERRINLVLLNRSGVPPREQG-TRRIKAL-KELERMGANV
ECLHADVAVREDLEQAYLHIKKKYGV-INGIIHAAGISSDGPIVDRGDEMFEYIYAPKVYGTWLLDSLTDDDNLDFFIMFSSVATIFSAFGQSEYVAANA
YMDAYSAYRN-KQGKQTLTINWSTWKETGMAYES---------GHALDTIFKALSTADAIEGLD-TLLHSNVT--RALVGEIKYEGSGA-----------
-----LLLERSGVPCSETIMNLIAEKKQKQQ-KPRSAKKNESGMNGVILHGR-------D---DGAYSEIERDLAECCKKVFGYHDFDIFDNFFEMGADS
LHLMKLQSEVEAQALTSLSMGDLFEYTTIFELAKYIERR-----------
>tr|J3AWZ0|J3AWZ0_9BACL Putative polyketide synthase component,beta-ketoacyl synthase family protein OS=Brevibacillus sp. CF112 GN=PMI08_04770 PE=4 SV=
DWSYRPTWKRAAFSD--WSAKRSAIIFHDVE-LAEAVEACKRQ--FAQPFRGGAPCAENGC--GLAD-DSQASYTDVLQTYWQ--KTKTEAILYMALSED
EFVEDQEQAARMLDATYDSLLHLVQALDEVNGAAAIRLAVVRLFDVLGSEPLNPWKATLLGLVRGIPLEFPDRNCQLIDISCQEQLVA---SGLLLQEIA
G-GQDELFALRGKAKWLPLYEPVSLPARS---GAALKDGGVYLITGGTGGIGLELADYIASHCQASLILLGRSFFPAKEEGKQDAIAQM-RQLEQKGAQV
YVCQADVSDFPALAATLQRVQQEAGA-IHGVIHAAGLPGSGLIQQAKKETSHQVILAKAAGCLNLNRILRANDLDFFVLCSSISTLSPMIGQSDYNAANA
FLDAYAEYRN-RDGNEAINLKWDIWKNVGMAVKS---------GIAPSPSFQAGGKELFVARLSQSLLFSTGT--VGTIGTIER-PPGS-----------
-----VHLEALKARCADRNVQVMAGKASVAERIDGNKPSDDFGQIGIDIFGKALAAQGKRPPLSAPATDLQKALCAIYENHLGIAPIGIADDFFELGGDS
LKAIHVSTSIRKQCQANITLTDFFQEKTIEKLAAFIANS-----------
>tr|A0A022PLI7|A0A022PLI7_PHOLU Amino acid adenylation enzyme/thioester reductase family protein OS=Photorhabdus luminescens BA1 GN=BA1DRAFT_00451 PE=4 SV=1
QWCRHPRWLPKPLGEA-KQNRAPWLIFGAQAAEL-SDLWQA-AAPGSIVVEDANEFLQQSTYRFSLRKDQPEDYQRLIDCLIQQQVLPERIIWCWTAAVI
EA---------A-FEQLAA---AIKALTGHHKAFNITLLS---RGLQAARVEACNAAPALGLLGILAAEYPGYSARHIDLDDD----TFATYQSLITELY
TDMQPTSITLKQGERELQTFTELDEIPR----RQILRDGGVYLITGGLGGIGQLLARHISDKCSKKLGILSRRETNTSE----ALFDALRKS----GAEI
MMLRADVADSAALNDALAQMRAKFG-AINGVIHSAGIEASGLLEHGTSQNWRHVMAAKVSGTQQLMTAISQDSDFVLLCSSLA-SLVGGIGQADYAAANR
YLDAVAHYWR-QQAIPVTSVNWDTWSEVGMAVDYAAR--RK-------ESVIGLSNQEGCAIFD----------------LAI----AGMEAQIVVSKFT
------T--VR--------RPQL-----------------------------------QNSSAISDSASPEEAVRQLWYELLGEETIHLEDDFFELGGHS
LLATQMISRLRDHFQHCLTLAEFLEQPTMARVVRSLSDDKK---------
>tr|A0A0Q0D9U0|A0A0Q0D9U0_PSEAP Amino acid adenylation OS=Pseudomonas syringae pv. aptata GN=ALO85_04588 PE=4 SV=1
DWCQAPAWRPALPPRSDSPLQGPWLVVMRGVAAD-NSMLFSL-PPDSVCIADAGD---SGTAVAIIARGDAQAYEQLFNTLAAQEALPSQIIYMAGGAQP
EHAA-----ITL-FTDLMS---LVQAYIPHAANTVLSLVT---EGACQVDPNSC-VATLSGVVRTLTWELPQIQCRHFDLPLA----NAAENETLLLQAL
QHIDPSTLALRKQTFHEPCLRALQVLQP----PQQFEEGGTYVVTGGLGGMGLALASHLAAKVKATLVLMSRSATVDVG----QALQALEQQ----GARI
QHMAVDCADREVFTAALHQVRRQHG-RISGAIHAAGVQASGLIQLSQANAWAQVMGSKVVGTDVLIEVLREEPEFIFLCSSLA-SVLGGLGQADYAAANA
YLDARAQACR-QEGMPVVSLNWDAWAQAGMRVAYDRA--HP--EQAPIDEVRGLTNAEGCQLFE----------------LAL----AQNTAQIVVSKAQ
------DLQQL--------INQLQRGGTTSA-------------------GRATALFDSGAERVAPRNAVEQEVAQLWQELLGGDMPGVLDNFFDLGGHS
LLGSQLISRIRSRFQQCLTLAEFLDEPTIERIARSLGSGAD---------
>tr|A0A0B6RM88|A0A0B6RM88_BURGL Putative non-ribosomal peptide synthase OS=Burkholderia glumae PG1 GN=BGL_1c19030 PE=4 SV=1
DWCRVPRWRDEAASAGRARLDAPWLVFADDTAV--AGRLAAHAPAGSLTIVPGERFAHADAACITLRANAADDYRRLLEWLGQASIAPSQIVYGWSAADP
LD---------A-FERLAL---LVQALGARHLATTLTLVT---RGWRTAQADDG-AATMAGLLQAVNWEFPKLLVRHLDRDDD----SDATLTALADELA
HATVPSTLAFAAGRRQTLRYVPIESEGE----SLAVRDGGTYLITGGLDGIGYEIAHHLATAGRGKLGLVSRSGLDRRR----QRVAALEQA----GAEV
LVLQADIGDAQQSAQAFSAVRARFG-EINGIAHSAGLEASGLLGSGTPQAWRRVLGPKVDGTRHLVAQLGETRDFVLLCSSLA-SVLGGLGQADYSAANA
SLDASARHLR-RRGIRAVSMNWDAWAETGMALAYAAR--AAKAGKGAAAPIRGLSNQEGRALFA----------------LAA----AGGEAQVTVSKYG
------SIERL--------IERELAQRHA-----------------------DSGARAGESRQDGGAETVEAFVSRLWRDMLGVDALTADDDFFELGGHS
LLATQLISRIRERYDHCLTLAEFLDMPTIARIAASIEAAQD---------
>tr|A0A0F6L077|A0A0F6L077_BURPE Amino acid adenylation domain protein OS=Burkholderia pseudomallei MSHR4000 GN=X980_3902 PE=4 SV=1
QWCRTVSWRDAPAARA-L-PPERWLVFGDE--------WFALAPAGSVLVREDDAFRAHGDNGYGVRPGEKADCDRLIARLAEQGGVPAHVVYGWAQTDV
DR---------A-FAGLAA---LLQALGAHPADFRVSLVT---KGARSARTDACAAAAPAGLLKAVRWEYPRIVCRHIDIDDA----SDATIDALRAELS
SEPATSSIALAGARREAPGFAALPAVAR----DDVLRDGGAYLITGGASGIGLELAAHIASRRRDRLALLSRSPHDENA----ARFAALDEA----AASV
LRLTADVAHAAQLADALRTVRARFG-RIDGVIHAAGVEASGLLETGTPDAWRRVMAAKVHGARHLFDQLAGDPDFIVLCSSLA-AVVGGLGQADYAAANG
YMDALAQHWR-QRGVAAIAIDWDTWSDTGMAFDHAAR--TRRSND-RPGALPGLANREGRALFD----------------LAL----AHDAPRIVISKRG
------FEQDR--------RDAP-----------------------------------TRARRAAAPGDAQAALVALWQELLGVEQVGVDDDFFDLGGHS
LLATQLISRVRDQYARSPTLGEFLEEPTIARILRAIDHTGG---------
>tr|F1TIW2|F1TIW2_9FIRM Beta-ketoacyl synthase (Fragment) OS=[Clostridium] papyrosolvens DSM 2782 GN=Cpap_0012 PE=4 SV=1
------EWKGKPVHTNKTEMPENIILFMDFNREHEIFAEQIKASINIVQVYPGSRYEKISDIKYVVNVEDKDSFVLLFNELKDRNIDLANIVHLWNYSKE
RSGIHLEQFDRSQYLSSYSLYFIVQVLSKLRTRSTIRIISSNSVVFEEDYI-EPQKSTVHAVANVINQENIGVKCFSIDSD--EN-IG--IYEVLLNELS
-DPSQELVTYRRNSRWVRDIVKLN--KGKFD-NIYFKSQGTYVITGGLGGVGSEIAKFIAKNYKSNIALIGRSNKETAI------IDEL----KEYGAKA
AYYKADVADEVSMSQCIGRIEEDFG-GITGVIHAAGIVKDCISVNSSIEDVKEVFAPKVKGTLILDKLLRKENLDFMILFSGMVSFYPNQGQSAYAGANM
FMDSFAFKRQMEQKARTIAINWWFWGETGMAAKPDIIESLKSRNLSPITNKQGIDAFKRILSTGAVQVLMNND-SQAPIEVAVQHSK--P----------
------TAD----SVAKGIVVKKGSNQIGLLK-----------TLTKKYLISKIDKLIGIVIDETDT----------------------NTAFLDLSIDS
ITLINLSSELEKDAGIMLYPTVFFEYNNVEKLSSYLLEE-----------
>tr|F1TBP3|F1TBP3_9FIRM 6-deoxyerythronolide-B synthase OS=[Clostridium] papyrosolvens DSM 2782 GN=Cpap_2600 PE=4 SV=1
------YWTEIEKEQIKPLTLKTLLVFEDIKGKDSPLVKFYENGCKVIKVSKEFSYKKINEDQYNINPYNKEDYQNLFSSLHKDGIAAEGIIYAFDLNRQ
EVADHFAAVEDGKVLGLIALINSMRVYN--LDETHIAVVTSNAFIVDKGYN-YPQAAVA-GLIRTIPHEYGNIKGVLIDIE--EN-SLERTLKLIADYLM
NQYKKEIVSIRNGRLFAQTFKKFC--INQDM-NLPLQDQGVYVIAGGLGGIGLEIAKAIAAKVKARLILIGRSPFPERS------IQDI----EAKGSQV
ITLAVDVCNEKQLTSALESIRTKFD-HINGVINAAGILEDALINRVTKEVYEKVTKAKILGSCLLDYATNKDNLDFFVIFSAMVTYFGNAGQAAYSCANA
FEDSFAAYRNFVKGKKTIVINWGVWEEVGLVADSVSKKSLEERGIIPLSTSEAIEGFYSCLTEKHFQFGIGKL-SKD-LENLIS--R--L----------
------ITT----KLSRSISNSLSGHFTMDIE-----------KLLKEYLLKKINELRENSSKPMNY----------------------KTSFLDAGLDS
ITIVNFTENFENETGIKLYPTVLFEYPTIQELSKYLLKN-----------
>tr|G5JEX1|G5JEX1_CROWT Polyketide synthase type I OS=Crocosphaera watsonii WH 0003 GN=CWATWH0003_B308 PE=4 SV=1
-------------------------------------------------------------------------------------------MHLWSLTKE
STTPDLDNLEQSQALGLYSLIYLAKAISNLTNQLQITVISNGLHEVIGEEELSPEKNTLLGAVKVIPQEYPNIQCRSIDIILSSTENEKLRGQNLVQEIT
SPPLELVIAYRNQYRWIQSFEPIQLTQSNN-IDNRLWLKGVYLITGGLGGVGLTLAQYLAQKVQAKLLLIGRSPLPERSHDSQDKIRKI-QQIEKLGSEV
QVVSADITDQKQMQFILTQVQDQWG-EIKGIIHCAGVADAGIIQSRTKESTDQVLAAKVKGTLVLDKLLGKANDFFVLCSSLATILHTKFGQVGYCAAND
FLDAFAYYKKAKYGTFTVTINWWDWGEVGMSVESEQWWSQKKRN-VDKSDLGSLGVFERVLGSNLPRVAI----SPRNLTGML---------QIIGEWFK
E-------------------SLLSAKDSPVYS--------E---------KTFYNKSKLITSDSDDNSPIEKVLVELWHELLGVEKIDVHDDFFELGGDS
LLSLQLTSKIKKSFDIELPAHSLIENSTIAAIAELIETKLN---------
>tr|A0A0L6JKS6|A0A0L6JKS6_9FIRM 6-deoxyerythronolide-B synthase, Aspartate racemase OS=Pseudobacteroides cellulosolvens ATCC 35603 = DSM 2933 GN=Bccel_1693 PE=
-------------------------ILEDVNGIGKEAVRLRNDGMTVIEVECGNEYKKSSTINYTIS-GDEEDFKKLFADLRGEKIA--RIVHMFSITSA
T-VDSVKKLDEKLDNGVLSLFHMYRSLESGVKDLDVVLLSQYVNEVDEKCI-NPENAAMFGLGKVINMENPEIRCRAIDVDGE------TNIEQMILEIY
AGYKEYNVAYRRGKRYIQELDCIDAEEY-REKEIKLKHDGVYIITGGLGGLGLETAKFLASKGKITIALLSRTKMPEREEKNGTDKKKDILYIEKTGARL
VCCSVDVSKEEELRETVARLKSRFG-RINGVVHSAGIGAGGSIRNDTEEIFKEVLKPKIQGTWLLKQVTGDDAPDFFAVFSSPITLMGGAGSGSYTSANA
YLDSFTAYNN-KLGNRTIAMSWAPWEETVKAAGLVMDK--SRHMFDILSTTEITGSFWEVLNKNSPMVIVGRINYKSILYLAFRI--------------S
-QRIRSQMERLSA------------RNET----------SRENLSILKTAD-----VKLTGREHGWYSTSEKQLANVLGQVLGYNELNINHNFYELGGDS
IIAARAVGILNKQMGLNIKIADLLKNPNLREFAQYIELK-----------
>tr|W4DAU6|W4DAU6_9BACL Putative polyketide synthase component OS=Paenibacillus sp. FSL R7-277 GN=C173_20446 PE=4 SV=1
-------------------------VLGGGGERERALASLQADTENVIPVTIT-DYCAKEGERFFIT-GDRTGYQWLFRQIGISGKV--QLVHMTSVGSV
NAADDYMELGTSMIDPVINLLTLIRTFQMQIQEAELVIVTRYAYLV-TDLV-QPVNAALHGFAKSFHWEFPQVGCKCIDIDDA------TELSVITREVL
CQSPYFITALRAGRRYYEELNPMSETTVHELRNVGIKENGLYLITGGFGGIGLELAKYLSGKKKVRLILLGRSRLPDTDA-------DMIKQMENSGSTI
IHYAADIADFDRMKQIMEEIRVIHG-PLNGIVHCAGNGMVI--HELSEDSLRGILRPKVQGTWILDRLTCNEPPDFICLFSSAMTLIGGYGAAGYTAANS
YMNSYASMRC-SASTPFINIRWPEWTDTGLAECKQTNL--RKELFEPLLLERAIRYFDWVLHHNVHDLIPGRINWGCELQLPIRF--------------S
-ESVNEEFHKRQQ------------LRP--------------------DAD-----SRIQVNNKTATRTIEQKIGSLIGELLSYEHVDYNQNFFELGVDS
IIAAKIINRIQNQLNCSLEVADIFRYPTVHQLSGHLETL-----------
>tr|B8I5I0|B8I5I0_CLOCE Condensation domain protein OS=Clostridium cellulolyticum (strain ATCC 35319 / DSM 5812 / JCM 6584 / H10) GN=Ccel_2383 PE=4 SV=
-------------------------FFSDKSRSCNEINRLEAKGIKVIEVNTGEEYGVLGKDKYSVG-YSQEDFYQLFSQESIKDIN--YIVYSPD-SGL
PDTSDIKILENKLENSVYNLFRLTKAWQKTGKDIKIVILSTYVNSVTEECL-NPENAALFGMAFVLKKEYPNLKIKCIDMDEG------CEAESIISEFQ
TVHKTRMIAFRNGRRYIEQLKRVKREQN-PSNSVKIRENGVYIITGGLGGIGLEIAKHMASGTNLNVIMINRSEMPERSQETEKDLKKSIMDIESLGSKV
TYYNGDVSDMQSMKLIIEDVIKNYG-KINGIIHSAGIAGNGAITK-DEKRIKEVMAAKVKGTWIIDSLTSNLNMDFLLLFSSAETLTTSAGQSDYTAANY
YMDTYCYYRN-KRNQPTFCINWAAWKETGMAKEHNADR---DGVFMVLSTANGVRVFDEVLKSGQPRVIAGQLNYNLLASLPVTL--------------E
-PELSAVLDRSKK------------TRKSD---------IIAGTTKQDTVD-----IKLTGKTDDQITKTEQAIGYIWASIFQSNEINVYDSFYDQGGDS
IFAMKITNVIRNTWGINISITDVMNNQSIYELGKYIDSE-----------
>tr|S0FJD0|S0FJD0_9FIRM Beta-ketoacyl synthase (Fragment) OS=[Clostridium] termitidis CT1112 GN=CTER_5158 PE=4 SV=1
-------------------------VFKNTNTLSNKLEMFKQHEKPVIEVSIGNKYNKVNDTKYEIE-NRENDYKRVIEEVKREGIS--QIIHLLTLTDN
EPIYSAEMLEEILNKSTHSLRYIVKGLHQSLKGVNIALISQYVETVDEKVI-RCENAALFGLGKVINVENYDIKCKFIDIDDS------TDVTNIKRELS
FENCESNIAYRNNKRFVKALDVLDIQKL-DNVNTEVRDEGVYIITGGIGNVGLEAAKFIASGHEVKIALINRSKMPERGQHQGTDIIRLINDIESNGSVV
EFFSADVSKEEEIIPLIDSFRCKFS-KINGVIHCAGIGVGGRVEDDSDEIFNKVLAPKVQGTWLLDKATENDKLDFFIAFSSPITLTGALGSGSYTSANA
YLDSFVMYRN-RLGKRTINIGINKFK----VKSNIIDD--DKRLFRPINEDDIANAFMLVFSKNIQSVIVGLLNYDNEIYLPFII--------------D
-NNLKQNMKLHRE------------KQVVQ---------LKTTVTNAKSTH-----YRLKGNNEQGYTETENLLGSVFCSVLGLDEIDIYDNFYELGGDS
IIAAKIVNIINKEKQLDIKITDLLRNPSIKLFAKTLDIN-----------
>tr|A0A061A1W0|A0A061A1W0_9ACTN Beta-ketoacyl synthase OS=Streptomyces iranensis GN=SIRAN6340 PE=4 SV=1
GWRYRVTWKPVSERLGTGVLGGCWLVVVPAEAWAAGVVRMLAGRGDVRVV---ESA--------------AVDRAGLADELRTAGGSVAGVFSLLAVESA
--------------SGLLRTAALVQALGEVGVGARLWVATRGAVSVGRSGVVSPAQALVWGFGRVAALELPERWGGLVDLSES--VDER-ALGRLAGVLA
PGSGEDQVAVRASGVFGRRLVRVVGSRTS--GDEGWRASGSVLVTGGTGALGAHVARWLVANGAEHVVLTSRRGLEAPGA--AELRDELAA----SGARV
TVAACDVADRDALAELLASI--PAEFPLTAVVHAAGVLDDGVLDALTPERFASVLRAKADAALHLDELTRGLNLSAFVLFSSITGSVGAAGQGNYAAANA
YLDALAELRR-AQGLPATSIAWGPWADSGMAGDDAMERRMRREGMPPMAPESAVAALRQALDLDDAVTVADIEWENFTRTLTAVR---------------
-------PSPLIAELAAVAG-------PGAATGADTVKVVTD-ADSASPLGERLSG--------LPRAEQDRALLLVRASVLGHGAVAAGRAFKELGFDS
LAAVELRNRLNAATGLRLAATLSYDYPNATALADHLRTE-----------
>tr|A0A046R169|A0A046R169_MYCTX Phenolpthiocerol synthesis type-I polyketide synthase PpsB OS=Mycobacterium tuberculosis OFXR-27 GN=Q637_03064 PE=4 SV=1
DWCHQLAWPIRPAVSADPPSTAAWLVVADNELCHEL-ARAADSRVS----------LSPPAL---AAGSDPA---ALLDALR--NPPVPGEL--LDI---
ESAYQV--FHATRRLAAA------MVASSATAISKLFIMTRNAQPISEGDRANPGHAVLWGLGRSLALEHPEIWGGIIDLDDS--M--L-AVRHVLTAAH
-TDGEDQVVYRSGARHVPRLQRRTLP---G-KPVTLNADASQLVIGATGNIGPHLIRQLARMGAKTIVAMARKPGALD-----ELTQCLAA----TGTDL
IAVAADATDPAAMQTLFDRFG-TELPPLEGIYLAAFAGRPALLSEMTDDDVTTMFRPKLDALALLHRLSLKSPVRHFVLFSSVSGLLGSRWLAHYTATSA
FLDSFAGARR-TMGLPATVVDWGLWKSLADVQK---TQISAESGLQPMADEVAIGALPLVMNPAAATVVVAADWPLLAAAYRTRG---------------
-------ALRIVDDLLPAP--------------------EDV-GKGESEFRTSLRS--------CPAEKRRDMLFHVGATVMGMPPLDPSAGFFQLGMDS
LMSVTLQRALSESLGEFLPASVVFDYPTVYSLTDYLATV-----------
>tr|A0A066Y530|A0A066Y530_9ACTN Uncharacterized protein OS=Streptomyces olindensis GN=DF19_21895 PE=4 SV=1
GRRYEVVWRPVTERPV-PGPAGHWLLVTPGADWAEAALGALAARGRVTVLERTGAG--------------PEDRAGIAERVAEAGGPVDGVLSLLALDER
PHPAH-----GALPSGVAALLGLVQALADLGTRVPLWSLTCGAVSAFDGPLLHPVQAQVWGLGRVVALEQPQVWGGLIDLPRE--PGAE-EWRRLCAVLA
GG-EEDQLAIRPGGARVRRLVPAPVP--A--GGPVWRPGGTVVVTGGSGALAPHLARWLADGGAEHVVLVSRRGPDAPGH--AALSAELAG----RGTGV
TALSCDITDRESVRALLREAA-RLGGPVRAVVHAATATRLAPLTATGAAELADVLGAKALGAVHLAELADPDDPPELVFFSSIAAVWGSGEHGAYAAANA
FLDAYAEQLR-QRGRAATAVAFGAWRSDELP-AELDEEQLERQGLPLLEPRLALAGLGRELA-GGPVALVDVRWETFAPVFASAR---------------
-------PRPLLDEIPAVRG-------ALRGAPPDAGGT-----SADGERLRRLAR--------LPEAARAREVLVVTSAVLGHSRPAPGRTFKELGFDS
LTAVALRNRLRAATGLPLPVTLVFDHPSPQALARFLTGR-----------
>tr|Q1MX75|Q1MX75_9ACTN Type I polyketide synthase OS=Streptomyces sp. NRRL 11266 GN=tmnAII PE=4 SV=1
SRRYEIGWRPSAERRT-PGPGGHWLLVTRDGAWAGAADTALRARGRVTVVALDERA--------------ADDRADVTRRVSAAGEAVDGVLSLLALDER
AHPGH-----PALPSGVAGLLGLVQALVELDVAAPVWSLTCAAVSALDDVPAYPLQAQTWGLGRVVALEQPQLWGGLVDLPER--PGDE-DWQRLCAVLA
GG-DEDQVAVRPGGLRVRRLLPAPAP--A--GGPAWQPSGTVVVTGGSGSLAPHLARWLADGGAEHIVLASRRGPDAPGH--AALAEELGG----RGVRV
TALSCDLTDRDSVRSLLERSA-EPGRPVRAVVHAATATHLEPLAGASAAGVADVLAAKALGAVHLAELLAG-EDAELVFFSSIAAVWGSGEHGAYAAANA
FLDAYAEQLR-GQGRKVTSVAFGAWRSEQLP-EELDEAQLTRQGLPLLDPEVALTGLGRELA-GGPVTLVDVDWETFAPVFASAR---------------
-------PRPLLDEVPAARG-------ALRSAADG-AGT-AA-AGGAGELLKRLAQ--------LPEAARGREVLVVTAAVLGHGRPAPGQTFKELGLDS
LTAVALRNRLRAATGLPLPVTLVFDHPSPQALARFLTGQ-----------
>tr|A0A0F7N228|A0A0F7N228_9ACTN Uncharacterized protein OS=Streptomyces sp. CNQ-509 GN=AA958_00665 PE=4 SV=1
GQRYEIGWRPAAERRT-PGPDGHWLLVTRTGDWADAAGAALSARGGVTVVELDERA--------------DDERAGIARRLSAAGEAVDGVLSLLPLDER
PHPGH-----AALPSGVGGLLGLVQALAGLGVAAPVWSLTCAAVKALDDVLAHPEQAETWGLGRVVALEQPQLWGGLVDLPER--PGDE-DWLRLCAVLA
GG-DEDQVAIRPGGPRVRRLLPAPAP--A--DSPVWQPGGTVVVTGGSGSLAPHLARWLADGGAEHIVLASRRGPDAPGH--EALAAELAG----RGVGV
TALSCDLTDRDSVRALLRRAA-ELGGPVRAVVHAATSTRLEPLADATAAGVAEVLAAKALGAVHLAESMDPDGPAELVFFSSIAAVWGSGEHGAYAAANA
FLDAYAQQLR-GRGRKVTSVAFGAWRSEVLP-EGLDEAQLERQGLPLLDPELALAGLGREVAGGGPVTLVDVDWETFAPVFASAR---------------
-------PRPLLDEIPAVRG-------ALRSAEAGGTGA-AD-GGDTGERLRKLAG--------LPEAARGREVLVVTAAVLGHSRPAPMRTFKELGFDS
LTAVALRNRLRAATGLSLPVTLVFDHPSPQALARFLTGQ-----------
>tr|A0A014MKN4|A0A014MKN4_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. PRh5 GN=Z951_43200 PE=4 SV=1
GWRYQIAWTPVSEL-SERALTGTWMVMVPQAELVTSAATMLERQGDVARIVLDGAA--------------DIDRAAVAERLRTADGAVGGVLSLLALDED
PCAEH-----TVVPRGLALNLVALQALVDAGVEAPLWVATRGAVSVTGSTLRSAAQAQMWGLGRVAGLEHPRLWGGLVDLPET--FDER-AAARLSGVLG
GGEFEDQVAVRTSGVFTRRLVRATAPRS---TARPWTARGSVLVTGGTGGVGGQVARWLASAGAEHLVLTSRRGPEADGA--AELRDELTA----LGAEV
TIAACDAADREALAAVLAAI--PERYPLSAVVHAAGVLDDGVLDAMSVERVAGVLRPKVDGARNLHELTEGLDLSAFVLFSSLAGAIGGAGQGSYAAANA
YLDALAQQRR-AQGLAATSVAWGPWAEGGMAVDGALEDRLRRGGMAAMTPELAVKALQQALDLQEHLAIADLDWERFVPAYTAVR---------------
-------ASRLLDEVPEARR-------ILAALGGGTAAV--F-ETGGSELRERLAG--------MSEAEQERALLLVTAMVLGFPSVESQRAFRELGFDS
LTAVELRNRLDAATGLRLPATIVFDHPTPVALARRLRTD-----------
>tr|Q8RJY2|Q8RJY2_STIAU StiE protein OS=Stigmatella aurantiaca GN=stiE PE=4 SV=1
EWLYESQWRRETPPLTASVGPGRWLILGDRGGVGETLMRRLEERGKCTFALAGNSFQRVSERRYEIRPGQTEDFQRLVQEVFR-SLPCKGVVHLWSLDGV
STQELTLAIHAAQPLGVESALSVVQSIAWAGLRDRLWLVTAGAHVAGGEGPVAVAVAPLWGLGGTIVQEHPELRCSRVDLSGA--RRKE-EIDALIETLW
-DGSEDQIALRGGERFVARLAHWTGERARRDGEVAIRSDGTYLITGGYGGLGLTFARWLVDRGARHIILAGRNGAPESA---RGAIEELRK----AGAEI
IAAKMDVADAEQTARVLEEAR-KTLPPLRGVIHSAVVLDDGVLLKQNRQRLERAMAPKVDGTWNLHRLTLDCPLDFFLLFSSLASMLGAPGQGNYTAAGA
FQDAFVFYRR-ALGLPAMTINWSPWSDVGQAVVANRGERLAQGGLQSINPEQGVRVLERLLQH-AQIGVMRLDLRQWRQFYPKNA---------------
-------SSPLFAELMRALN-------TA---------PTKV-ASDSSVRVALQSL--------EPGPRRREMLEHLQAQVLRMSDLDRSTPLRSLGFDS
LVAVEFRNRIEASLGLTLSATLAWNHPTIEAMTTHIADK-----------
>tr|A0A089VFG6|A0A089VFG6_CHOCO Polyketide synthase OS=Chondromyces crocatus GN=croB PE=4 SV=1
QWFYEIQWWPSPLPAKTAAQGKRWLVFADQQGVGEALRAEIESRGTCVVAFLGEQLRQVSPGRYEVSPDRAAL-----AALLA-RVDLTGVVHLWNLDLV
PPAKTSLTLHDAERLGCGSLMALVQAIAGAGMRDRLWIVTAGAHAVGTRG-VAIAQAPAWGLGATIAHEHPELRCTRIDLDGG--AGPA-DASTLLAALG
-VDGEDQIALRSAVRYVARLARTAS-AAQQDLPTALRDDGTYLITGGLSGIGLTVAEWMVQRGARHLALVGRSGASPAA---ESALAPLRA----AGAEI
TTFQADVSQPEAMARVFSQID-ASMPPLRGVIHSAVALDDGVLLQLDPARLRSVMAAKMDGAFNLHLLTQERPLDFFILFSSLASILGSPGQGNYTAANA
FVDALAHHRK-SLGLPALSLNWAPWSEVGLAVVTKRGERLAYRGLKSITPEQGKDVMERVLAS-SQVGVMLLDLRQWRQFYPRSA---------------
-------SSPLLSEIAREQG-------NG----------APV-EPEAPLRSVLIAE--------ESVERRRTLLEHVQGHVLRLSQIDPQTPLKSFGFDS
LMAVELRNRLEASLGLTLSATVVWSYPTVAALVAHLASK-----------
>tr|Q6DNE5|Q6DNE5_9CYAN CurH OS=Lyngbya majuscula GN=curH PE=1 SV=1
NWLYQLQWQPSEVKETPLATSRMWLLFVPEGVWAEQLTSSLAQLDQYVVVSPGDDFRYLSEYHYQVCPTQKESFQQLLQKIVEKGVTLQGVVHLWSLL--
SDSQQL---NQAQELVCGSTLHLIQALGEVFDSQPLWLVTQGAQCIAA-TTIHVQQSPLWGLGRVIALEHPEFKCHRVDLDPD--NASE-GVEMLLQELL
-PDAEDQVAYRQGERHVARLERFVPQSSGEEQKKEIQAQGSYLVTGGLGALGLEVSKWLVDKGARHLVLMGRRSPSAEA---QIKIAQLED----MGVKV
SVQLADVSCSQQVSQMMERIE-RELPSLRGVIHAAGVLDDGVLQNMSWQQFVKVMLPKVQGTWHLHQLTKDLPLDFFVCFSSMSSLLGNLGQGNYAAANE
FMDAVAHYRR-SMGLPGLSINWGAWASSGMAASGQHQQRLETIGIRAIEPQQGMQALGSLLSQ-PQVGVLPINWSKFVSTLPGGQ---------------
-------KMPFLEALISTEP---------------------S-LTQKSAFREQLEA--------AAVSERQELLTHIRAKALGWRKIGMRQPLFDLGLDS
LMAVELKNRLESSLETNLSSTLLFDYPTVEALVEYLAND-----------
>tr|F4Y424|F4Y424_9CYAN CurL OS=Moorea producens 3L GN=LYNGBM3L_74440 PE=1 SV=1
QWVYELKWETKKHQQLSPNKPGNWLIFADQQT--QALKTVLAKQNNCLIVTPGSSYKQLDDQHYQLNPTNAQEFQQLIKELFTTQDTLEGVVHLWNIN--
TSTEEL---EAAQELGCASVLYLVQALVSNSQSSPLWLVTQGTQNVEENPKLAVQQAPVWGLSRVIALEHPELKCRRVDLDQT--RNSE-ALEALGKELL
-PDDEDQIAIRGGVRYSARLARRTQ----KEQQIAFGTEGSYLLTGGLGALGLEVAQWMVKQGARHIVLNGRRTPSETA---QETIQQLEQ----TGAKI
SVILGDVSKEEDVASILKQIE-ASQAPLRGVIHAAGFLDDGVLQQMSWERFRKVMAPKLQGAWYLHQLTQKLPLDFFVCFSSIASLLGSPGQGNYAAANA
FMDTLADYRR-SMGLPGLSINWGAWAQGGMASRSQHQSRLRTTGMNLITPEKGLQVLGELLSQ-VQVGVFPINWSQFLGQLPVGH---------------
-------TISFLEAFASRKL-------QK------------E-TTKDENFLEQLAL--------AIESERNQILIYLQGKLLGFDLPNPELGFFDMGMDS
LLTVELRNLLSSNLGCSISAAELFGTSNIQNLAEHLIKE-----------
>tr|E3FQI4|E3FQI4_STIAD Tylactone synthase modules 4 & 5 OS=Stigmatella aurantiaca (strain DW4/3-1) GN=STAUR_1685 PE=4 SV=1
EFLYSFLWSQKALGAGAGSSPGRWLVFADHGGVGLAVARALKEAQVCTLVHPSPGIATLRHEDYHLDPSRPEHFTALMEAVCPQKHLPPGILYFWGLDLL
GTAAEPSAWEQTQALGCGPLLRLLQALGPFREMA-VQLVTRGVFVPGERAPVHIEQSALLGLFNTFRIERPAFRCLHMDLEPG--PRRL-EVRQLLQEVL
-HEGEEQVAFRKGLRFVSRWERMKDLPASSDEPPIIRAQGTYLLTGGLGALGLEVAQWLVNQGARSLVLLGRRGPSAEA---LPLLERLRA----AGASV
EVLQADVTELGSLTQVMAHLRTPGRPPLVGVLHAAGLLDDGTLQELTEERFLKVMEPKVKGTWNLHLLTKDLPLDFFVCFSSMASALGSLGQGNYAAANA
FMDALMHQRR-ALGQPGLSINWGSWASVGMAATPQHRKQAAARGIHTLPTPLALAALGVLLRG-PQAGVAAIDWERFIRQVRLGI---------------
-------PLKLIEVLVASAS-------RG---------SSAP-AESPELFRARLRE--------APPLQRRELLLFMRARMLGFAKIDPHHRLVELGLDS
LSSVELKNHLEITLGCSLPAALLFDFPTLDALAVHLHDE-----------
>tr|Q091C2|Q091C2_STIAD CrpB-like protein OS=Stigmatella aurantiaca (strain DW4/3-1) GN=dkxH PE=4 SV=1
EWMYRMTWSPCDAAEKRPSGQQHWVIFTDEGGFGNELMALLSQRGRFTPVRKGREFSSSPDGF-QLNPEESGHFKSLIASCG--NEPVSGFLYLWGLDGS
SNEEPSLGLEAAQVTGCVGALYLTQALARASWSARLILVTRGTQRLASDQGPRIAQAPLWGFGQAVATELPELRCLRVDLAAE--PRLG-DLGTFIRALS
-PGSEAQLAVRNGALHAARVERTRLRTGAA-KKVAISAASSYLIAGGLGGLGLRLARWLVDRGAQYLVLLGRSGPSPEA---QRQIEALEA----KGVRV
QVALADLASHEEVAAVLAGLR--SAPPLRGIFHSAGVLRDGTIGNQTSGNFHEVLAPKVQGAWNLHLLSSGMELDFFVCFSSVASLIGTPGQSNYVAANA
FLDALAHLRH-AQGKPAITINWGSWAEAGMAARRAEAGRPGTLGFGAIPVEQGLSVLEQLLGS-HQLGVFPVDWTRLTEQLPGLA---------------
-------SQALVRAFVRGVP---------------------L-QNQPPVFLQQWEL--------APPNRRMELLRHVTAVTLGMAKISGGERLFELGVDS
LLAVELKNRLASSLGKSLRSTLVFDFPTVNGLVAHLAGE-----------
>tr|A0A0F7BMD0|A0A0F7BMD0_MYXFU Polyketide synthase OS=Myxococcus fulvus 124B02 GN=MFUL124B02_24080 PE=4 SV=1
DWLYRVTWRPCASQDERPT-GQHWVLFIGDGGVGDTLAALLEQRGRVTRVRQGR--TLD--------PARPDSFDRLFSEWD--GAAPHGLVYLWDDDE-
E------------ASSCEGALHLVQALVRASWTPRLIIITRGTQTLSSDHEPRIAQATLWGLGQAVSTELPELRCLRVDLPRE--PAKG-EAEACLRAFA
-AEQEQQVVVRTEGLYTARLERARARAVT--RKLELSSEASYLVAGGLGGLGLRLAGWLADRGARHLVLMGRHGPSAEA---QRQLDALAT----RGVHV
RVALADLASRDELAAVLAPSN--DAPPLRGLFHAAGVLHDGTLAHLTAEHFREVLAPKVQGAWNLHVLTAGMPLDFFVCFSSAASLLGTPGQSNYVAANA
FLDALAQLRR-AQGRPALTLDWGSWAETGMAARPVSTRSPTALGFGAIPVERGLEVLERLMGG-SSLGVFPVDWTRLAEQWPGLS---------------
-------RQAFFQGLLGGTP---------------------M-EPRAPAFRARLDA--------AAPNRRLELLRHVAARTLGLARLSGGERLFDLGFDS
LLAVELKNRLAGSLGKSLRSTLVFDFPSVAGLVTHLAGE-----------
>tr|L7UED9|L7UED9_MYXSD Polyketide synthase OS=Myxococcus stipitatus (strain DSM 14675 / JCM 12634 / Mx s8) GN=MYSTI_06013 PE=4 SV=1
EWLYRVTWSPCASPEARVS-DPHWVLFTDEAGFGEEVAALLEQRGRVTRVRQGSEFLQGPTGF-QVDPARPAHFEQLFSTWD--GASPQGLLYLWGLDAG
DSLE------SAQRSGCVGALHLVRALAQRSWAPRLVIATRGTQALPADQGPRIAQAPLWGFGQAVSTELPELRCLRVDLPGE--PVPT-DAEALLRACA
-PEQECQVAVRTGALHTARLEHARPRAMS--RKLEVSPAASYLIAGGLGGLGLRLAGWLADRGAKHLLLLGRRGPSPEA---QRRIEALEA----RGVHV
RVAQADLASRDAVAAALSEAR--GAPPLRGLFHVAGVLHDGTLVHQTAEQLHEVLAPKVQGAWNLHELSAGLPLDFFICFSSAASLLGTPGQSNYVAANA
FLDALAHLRH-AQGLPALTLNWGSWAETGMAARSAAEGTSSAMGFETIPVERGLEVLERLMGG-GSLGVFPVDWRRLGEKWPGLS---------------
-------RQAFFQGLLGTTP---------------------H-APRAPVFRAQLEA--------AAPTRRLELLRHVSSRTLGLARLSGHERLFDLGFDS
LLAVELKNRLASSLGRNLRSTLVFDFPSVAGLVSHLAGE-----------
>tr|F8CN03|F8CN03_MYXFH Polyketide synthase type I OS=Myxococcus fulvus (strain ATCC BAA-855 / HW-1) GN=LILAB_29640 PE=4 SV=1
DWLYRLNWTPSAVTEDHSS-SAHWAIFASEDGFGSELVQVLSRRGRCTLVRKGEAFSSTAQGF-HVNPSSPEDFARLAQGWA--HQPPTGVLYLWGLDDA
GGDADAR-LDAAQESGCLGALRLTQALTRGA-GTRLVLVTRGTQRLPADHGVRVAQAPLWGFGQAVATELPELRCLRIDLPAE--PRPE-DLGTFVRALA
-PDAESAAAIRGGSLFTPRLERARSRAASS-RKVPMVADATYVVAGGLGGLGLRVATWLADKGARHLVLLGRSAPSPES---RARLDALEA----QGVEV
RVAQVDLASRGAMAELFASLR--DAPPVRGIVHTAGVLRDGTLANQTPEQFREVLAPKLQGAWNLHALSEGLALDFFVCFSSAASLIGSPGQSNYVAANA
FLDALVHLRH-AKGLPALTLNWGSWAETGMAARRAASARPGAQGFGSIPVEQGLGVMERLMGG-QQWGVFPVDWARLAEQLPGLA---------------
-------RQALVQGLLGSVP---------------------R-RVQAPAFRAQLDA--------APENRRLELLRHVSAATLGMPRLVGSERLFELGVDS
LLAIEIKNRLASSLGRSLRSTLIFDFPTVNGLVAHLADE-----------
>tr|A0A0H4WS89|A0A0H4WS89_9DELT Malonyl CoA-acyl carrier protein transacylase OS=Myxococcus sp. (contaminant ex DSM 436) GN=A176_002591 PE=4 SV=1
DWLYRVAWAPRAVPEEQGA-GQHWAVFVNAEGFGSELVQVLTQRGRCTVIRRGETYSQGAEGY-RVNPSSTDHFERLVQDWA--HAPPTGVLYLWGLDEG
PVSPGTLHLEAAHVSGLTGALHLTQALARSA-AARLVLVTRGTQSLASDQGARVAQAPLWGFGQAVATELPELRCLRIDLSAE--PRAE-DLGAFVRALS
-PGEESSAAIRDGGLYTARLERARLRASSA-KKPAIVADAAYVVAGGLGGLGLRVALWLAEKGARHLVLMGRNAPSAES---RAQLDALAA----KGVQV
QVALVDVTSRDAVAELFERLR--SGPPVRGIFHSAGVLRDGTLANQTSEQFRAVLAPKVQGAWNLHELSARMALDFFVCFSSAASLIGSPGQANYVAANA
FLDALAHLRQ-AEGKPALTLNWGSWAETGMAARRAASVRPGAQGFGSIPVEQGLSVLERLLGS-QQWGVFPVDWARLAEQLPGLA---------------
-------RQSLVQGFISAVP---------------------Q-RAPAPVFQVELDA--------APANRRLELLRHVSATTLGMPKLAGNERLFEVGVDS
LLAIEIRNRLASSLGRSLRSTLIFDFPTVNALVAHLAEQ-----------
>tr|S9NT03|S9NT03_9DELT Malonyl CoA-acyl carrier protein transacylase OS=Cystobacter fuscus DSM 2262 GN=D187_009447 PE=4 SV=1
DWLYQLTWTPHAATEERPA-SQSWVLFADEGGFGAELMEVLTQRGRCTLVRRGHEFSSGPDGV-RLDPGSAAHFSQLLSAWE--GEPPTGLLYLWGLDED
LDTGFSLGLEAAQIPGCLGALHLTQALGRTSWATRLVIVTRGTQRLPSDRAPRIAQAPLWGFGQAVATELPELRCLRVDLAGE--PRRE-ELGAFVRALF
-PEGETQVAVRGGALYTARLGRARLRASPE-KKSAISAEASYLIAGGLGGLGLRLAVWLADRGARHLVLLGRRGPSPEV---QGQLEALEA----RGVRV
QVALVDLSSREEVAEVLNGMR--STPPLRGIFHSAGVLRDGTIGNQTAEHFREVMASKVQGAWNLHELSAGLELDFFVCFSSVASLIGTPGQSNYVAANA
FLDALAHLRH-AQGKPATTINWGSWAEAGMAARQADTGRPGALGFGFIPVAQGLSILERLLGG-SQLGVFPVDWTLLTQQLPGLA---------------
-------SQALIQAFVGGVP---------------------L-REQPSAFRQQLDA--------ALPNRRMELLRHVEATTLGLAKIAGGERLFELGVDS
LLAVELRNRLMSSLGRNLRSTLVFDFPTVNGLVAHLAGE-----------
>tr|Q1D4F0|Q1D4F0_MYXXD Polyketide synthase type I OS=Myxococcus xanthus (strain DK 1622) GN=MXAN_4298 PE=4 SV=1
DWLYRLNWVSRAVTEEHSA-NQHWAVFASEDDFASDLVQVLSQRGRCTLVRKGESFSSTPEGF-RINPANPEDHARLVKAWA--NQPPTGLLYLWGLDEG
GHAGDAGRLDAAQELGCLGALRLTQALAHGQ-GARLVLVTRGTQSLPSDHGARVAQAPLWGFGQAVATELPELRCLRIDLPAE--PRSE-DLGTFVRALA
-PDGESGAAIRGGGLYTPRLERARSRSVAA-KKVSIIGEATYLVAGGLGGLGLRAANWLAAQGARHLVLMGRSAPSPEA---RAQLDALES----QGVKV
RVARVDIASHDAMADLFASLR--EAPPVRGIIHSAGVLRDGTLANQTSEQFREVLAPKLQGAWNLHALSQGMALDFFVCFSSAASLIGSPGQSNYVAANA
FLDALVHLRH-AEGLPALTLNWGSWAETGMAARRAASARPGAQGFGAIPVQQGFSVLERLIGS-QQWGVFPVDWTRLAEQLPGLA---------------
-------RQALVQGLLGSVP---------------------Q-RAQAPAFRAQLDA--------APPNRKAELLRHVASATLGMPRLSGNERLFELGVDS
LLAIEIKNRLASSLGRSLRSTLIFDFPTVNGLVAHLAEE-----------
>tr|A0A0A6PNY8|A0A0A6PNY8_9GAMM Uncharacterized protein (Fragment) OS=Candidatus Thiomargarita nelsonii GN=OT06_07260 PE=4 SV=1
ECFYQLTWQPKPGVSKEHQSTGTWLIFADTGGVGKALAQLLQKRGASILVYAG-----------EINPANPTDFENFFQK--RLDTNLQGIVHLWSLDAP
LPDELTVTALEQ-SLGCASVLHLVQTLEHY-NSTSLWLVTQNAVPVKSGHLTALAQSPLWGLGKVLALEHPDKWGGMIDLAPVGD-----NAATLLTEIL
APDTEDMIAYRDGQRYVARLVPNCLTDSS---AISLATKASYLITGGLGALGLRVAQWLIAQGARHLILTSRRQP---SKQAQETI----NQLRQDGVNV
LVANADVANQSEISMLFETIGNTM-PPLRGIVHAAGVVGYEPIKDIALDSLQAVLRPKVQGAWILHQLTQKMSLDFFVCFSSIASVWGSKGQAHYAAGNH
FLDMLAHYRH-GLGLPALTINWGPWADDGMASSEQAQTWLNRQGVETLPPQSAIEALSYLLGTKE--CQCTVNWSLFKEIYTLREQ------RPLLEHIK
VSQPQTVVEIPPVDILQQLKNAQKSDG---YEL-------------------LTTYLQEEVTKIVG---------LEFSE-----WPALQQGFFEMGIDS
LMAIELKNRLVASLGASLPATLIFDYPNIQDLAKYIGHK-----------
>tr|A0A0J6WI14|A0A0J6WI14_9MYCO Phthiocerol/phenolphthiocerol synthesis polyketide synthase type I PpsB OS=Mycobacterium chlorophenolicum GN=ppsB_4 PE=4 SV=1
EWFCALTWPVKPLAE--APSHGAWLVVGDA-RIGEAMARLLGGPVTL-----------------------AAGDDGLADAVA-----ATHVLY--APQER
DGDELGYELFEAGAI--------A--SAASPARPALYLVTRNAQPVSEGDRANPAQAVLWGLGRTLALEHPEIWGGLVDVDASVPA---PVTARW---VL
AGDGEDQVVYRAGTRRVARLVHQPPTAAG---TAVLDPNRAHLVIGATGNIGPRLIEQLAAMGAKTVVAVSRNPG----GRLDELT----ARLATTGTTV
VTAAADASDETALRALFDRFGTDL-PPLGGIYLAAMSGGPVTLAEMTHDDVVAMFRSKMDAAALLHTLSLGHPVEQFVLFSSISGVLGSRWLAHYAATTT
FLDTFAFARR-AAGLPATAINWGLWKSLADVQEGFEKQATAESGLEPMDDDTAIEALRLFVGPVAP-ARATADWPRLAAAYHTRAQ------LHILDDLL
AEDAG--TQAALTPFRGELRAADPERR---RDL-------------------LADHVGAQVAAAMG---------LASAH-----TLDPTVGFFQFGMDS
LMSVTLQRSLSESLGEVLPASVVFDYPTIEALTDYLASV-----------
>tr|A0A0J6VRH7|A0A0J6VRH7_9MYCO Phthiocerol/phenolphthiocerol synthesis polyketide synthase type I PpsB OS=Mycobacterium obuense GN=ppsB_2 PE=4 SV=1
EWFCDLTWPVKPLVA---AEQARWLVVGDV-RVGEAMAHLLGSPVTR-----------------------AAADDGLAEAMA-----ATHVLY--APDAG
DAGDLGYGLFETGAI--------A--AAASPTPPAVYLLTRNAQPVNEGDRADPAQAVLWGLGRTLALEHPDIWGGLIDVDASVPA---PVAARW---LL
AGDGEDQVVYRAGARRVARLVHQLPTAPA---SAGLNPDVAHLVIGATGNIGPRLIEELARMGAKTVVAVSRNPG----GRLDALT----ARLAAAGTTV
VTAAADAADEAALSALFDRFGTDL-PPLGGIYLAAMSGGPVTLAEMTHDDVVAMFRSKIDAVALLDTLSLDHPIEQFVLFSSISGILGSRWLAHYAATTT
FLDTFAFARR-AAGLPACAINWGLWKSLADVQTGFEKQATAESGLEPMADDVAISALRLFTGPGAP-ARTTADWPRLAAAYHTRAQ------LHILDDLL
ADDAT---TTALTAFRTALRDTPPEQR---KDL-------------------LGDHVGAQVAAAMG---------LASAH-----TLDPTVGFFQFGMDS
LMSVTLQRSLSESLGEVLPASVVFDYPTIEALTDYLASV-----------
>tr|X8FDM2|X8FDM2_MYCUL Short chain dehydrogenase family protein OS=Mycobacterium ulcerans str. Harvey GN=I551_3205 PE=4 SV=1
SCHYRVGWPTKPLADTETASGTRWLVFADA-ELGAELGLAAGAQTVD--------------------PSALTEESELLAALG-----VEHVVY--APPAG
KSLDAAYQLFHQVRL--------V--AVKASLTAKLLLVTRNAQPIAEGDRANPAHGVLWGLGRTIALEHPEIWRGIIDLDESMPA---ELAAPK---IL
GTDGEDQVVYRCGGRHVPRLQRRTAPAVA---PVTLDPNSSQLVIGATGNIGPYLIRQLAQMGAKTVVAVSRNPG----QPLQELA----ESLAAEGTNL
VIEAADATDEAAMTALFDRFGADL-PPLDGIYLAAFAGGPVLLNEMTDADVRAMFAPKLDAAALLHRLSLKVPARHFVLFSSISGLIGSRWLAHYTATSG
YLDALAYARH-ALGLPATTVNWGLWKSLADAEHDA-SQVSVGSGLLPMQDEVAIGTLPLLMNPAAG-VHSVADWPLLAAAYRTRWS------LHIVDDLL
RDFAE--ASTIPASHLS-----AQEVR---TEF-------------------E-AGLRRIVAREL----------RVSES-----DLETDRPLAELGLNS
LMAMAIRREAEMFVGIELSATMLFNHPTVASLASYLANR-----------
>tr|A0A0A6P3X6|A0A0A6P3X6_9GAMM Uncharacterized protein (Fragment) OS=Candidatus Thiomargarita nelsonii GN=OT06_50335 PE=4 SV=1
DWLYQIEWQSQPRSSAEIQSADRWLIFADQGGVGQALAEFLETRGYCVLVYAG-----------KVPPMRLADFKRLFNE--EK-ISISHIIHLWSLDAA
LSEELSLSALEQAQLNCGSVLHLVQTLCNKSVLPRLWLVTRGAVPIGQ-HPLSLAQSPLWGLGKVVALEHPEFWGGMLDLSPDATF---DETGMLLAVIQ
DSQGEDHIAFRNGQRYVARLVAKPPELRS---SVGFDAHYTYLITGGLGALGLKVAQWMVAQGVRYLVLTGRHGAS--TNQAQETL----KQLEQAGAQV
RVAKADVANQEDMSRVFAEMEAEM-PPLRGIIHAAGLLDDGVLHQQNWERFKRVMAPKVAGSWHLHTLTQEQQLDFFVCFSSIASLLGSPGQGNYAMANA
FMDALTYYRQ-AQGLPSLSINWGPWAGTGMAANLDHGR-FADRGIKTLQPDMAIAALEYLLGTDC--VQSSVDWNLFKAFYEATER------WSLLEQLT
EVPTERGTESV-PTILQDLENASAKER---WEW-------------------LISYLQGEVAKILG---------FPPSQ-----LPDIQQDFALMGIDS
LMAIDLRNRLQTKLGRSMPST-----------------------------
>tr|A0A0C5PRK7|A0A0C5PRK7_9FIRM Mycocerosate synthase, 6-deoxyerythronolide-B synthase OS=Pelosinus fermentans JBW45 GN=JBW_00049 PE=4 SV=1
---LHPYWKEQAIAQEAPTYTQHLVMLCETNKISAMIESNGVRCLTLESQQSGIEER--------FQIYAVQAFEEIQSILKEKTKG-------------
--------------------------------NVLIQIV-------ISTQQEQQLFSGLSGLLKTAQLENPKFIGQLIEVEPGEDAEGI-VEK--LKNNS
QSLIDNHIRYQDNKRYVIGWNEVALKEAV---KIPWKDQGVYLITGGAGGLGLMFAKEIAHKVKGILIFTGRSP---LDEDKQSKIRELES----LGTLI
TYKQVDVTDKQAILDVIQSIQKNFG-RLNGIIHSAGIIRDNFFIKKTKEELEAVLAPKVTGLVNLDEATKDLNLDFFILFSSITGALGNLGQADYATANA
FMDAYARYRNSLRQGQTLAINWPLWKEGGMHINEDAEKMMMNSGLIALETTTGIEALYQGVSSGKDQVMVI-------------E--------GDIERLH
TAF-------LGQPSVT------------------------GGA-KISVIVD-EKKVVPTIGQDLLQEKALNYFKKLLSAVIKLDRIEADAPLEQYGIDS
VMVMQMTNQLEKYFG-SLSKTLFFEYLNIQELTGYFLIS-----------
>tr|A0A089LDE5|A0A089LDE5_9BACL Uncharacterized protein OS=Paenibacillus borealis GN=PBOR_19450 PE=4 SV=1
---YAPEWVEAALPQE----LSSIVVFGSAALT-DSIREQGLAPDRCIQVQAGAEYARLSS-TEYVNPGQAADYRLLE-ALNTQGVELQHIVHGWNVNGG
AGAGAGDAL--EDTDSLQEGLAEFLEAQMDQGLYSLLHLLQAAAYDSAEHVLTPLNEMAAGLAHSISADHPLFQLSLVQLNAEAPAEAAELVQ---ELLP
PQAGGTEIRYDGGARYLRKLLPQ---LHQA-GESRFIRGGVYIITGGTGALGMLVAAELAATVQARLVLAGRQP---VDAAIQAKLEHLAG----LGA-A
VYLQADVADMDSSVRLIGQAKARFG-GINGILHCAGIGETVKAAESSKAGFARILGPKVSGTLNLDLASKDEALDLFILFSSTSAQIGDMGAGSYAAANS
FLDRFAVYRDRLRQGKSVSINWPLWQDGRYQVVAAQQQVLAYYGMHLLDSRTGLDILEAVLKEDVVQAFVGYG---------DPHK------I-------
-GQ-------TGQAGQA-------------------------------ATA--AQSASSSVDSGELLVRTQAYLVSLLAKTLGIERIGQASPLDAFGLDS
IMILELNESLQREFS-GLPTTLFYEYNTVESLAGYFTGH-----------
>tr|T0JQ63|T0JQ63_9FIRM Polyketide synthase PksN OS=Sporomusa ovata DSM 2662 GN=pksN PE=4 SV=1
---LRPCWQEQGPAGQGLEYDRQLVMLCEPGDIIESIQTAGVRFLTVEAKEQGIAKR--------FQAYTTKAFEEIQTILKQKTKD-------------
--------------------------------KVLFQIV-------VFNQGEQRLFSGLSGLLKTAQLENPRLTGQLIEVEPGESAAGL-AEK--LKENR
QSPVGSHICYQDDKRYVAGWREIPSPEEV---RIPWKDKGIYMITGGTGGLGLLFAREIAQQVKNTLILTGRSP---LTDGKQAQLEELEA----LGACA
VYRQTDVTQKQAVTDLITGIQEEFG-GLHGIIHSAGMIQDGFIIRKTSDELQEVLAPKVTGLVNLDQATKELALDFFILFSSVTGAFGNPGQCDYAVANA
FMDAYAKYRTALRQGQTLSVNWPLWKDGGMKVDAKIENSMRNMGLVAMKTTTGIRALYQGIALGFEQMVIM-------------E--------GDRKRLH
EVF-------LGQLINT------------------------ETT-QT-PGVE-QNKVVTADEQDLLGEKVVDFLKQLFSSIIKLHRIEEDAPLEKYGIDS
VMIMQLTNQLEKRFG-SLPKTLFFEYQNIQELSEYFLQS-----------
>tr|A0A0K6JV40|A0A0K6JV40_BACIU Polyketide synthase PksM OS=Bacillus subtilis GN=pksM PE=4 SV=1
---MIPVWEPVSSDTESF--AGTRVVLCGAAEADAFIKH---PQVSFIDIRPA--------------------DEGIADKLRAYG--SIDHVLWIAPSHR
GSIGSDGQE--EAVLHLFKFLKACLQLGYGEKQLEWSLVTVQAQHE----AVQPAHASIHGFAGTMAKEYPHWKIRLLDLEKGCTWPVNH------FALP
TDLGHA-WAYRNQQWHQQQLI-----HSLS-GDTLYRKGGVYVVIGGAGYIGEAWSEYMIRRYQAQIVWIGRSQ---LNAAIQSKIDRLSA----LGP-P
FYIAADAADKHSLQQAYDQVKMRHP-HIHGIVHSAMVLFEQSLEKMKPEEFTAGLAAKIDVSIRMAQVFRQENVDFVLFFSSLVAHIKNVKQSHYASGCT
FADAFAHRLSQS-ACPVKVMNWGYWGNSEAAEDEHY-VQLMQIGLGLIEPAEAMKALEALLSGPVSQTAFIHTTKPVATSAGIFEKLKPYCYTDL----S
EGFESVFIVA-------AS---------------------SNGLVKNVIL-PE---EAGQSKHALLREKSTEYMKKLIGETLKISKIESSEPLEKYGIDS
IVVVQLTNTLRKEFD-HVSSTLFFEYQTIDALVDHFIKT-----------
>tr|S4XSZ3|S4XSZ3_SORCE Uncharacterized protein OS=Sorangium cellulosum So0157-2 GN=SCE1572_03905 PE=4 SV=1
---YTPEWVPSPLPALHPEVPGPVLLLDVDGALHGALQRGGGRQAPVVLVHPGPTFAATG--ESTF-PGDAGSF--LVDALAAHGLLPRSVVCAWGEDHP
DLDEGALRAGLESGLYTLSALSQALAAQKGQP-VQILHVHRA--LD---TGPRPEADALASWVVSANLEGPGRVVKALTIVGSASP---SLAEIVCAELA
PDRGDAVVRIEGGARWVRSLRA----DLLE-GQGALRRGGVVLLAGGTGALGRIFARHLAESAGARLVLVGRSA---PAERHQRQIESLRA----LGA-A
IYVQADLARRDEVVAAVEQARARFG-DIHGVIHAAGVLTEGYVAERPRSAIEEVVAARVLGALHLDAATRDERLDFFVTFSSTAAELGGPAQADYAFANG
FLDRFAALREEARAGTTRSIGWSPWEVGAFD---AS-----------------------------------VTEWLRRAARAAI----------------
---AG---AR----------------------------------AADAAGAPA----------DSRMAAVGRELLDVAAQLLKQSEMDIETELNEYGFES
ISLIEFTNSINRRYGVELMPTAFFEHRTFGALARHLLDT-----------
>tr|A0A060DNV8|A0A060DNV8_AZOBR Uncharacterized protein OS=Azospirillum brasilense GN=ABAZ39_27265 PE=4 SV=1
---LAVEWQTAALPAGAP--LGPYLLFDQGTRRAEALRRLGDVAAALVLVQPGERFEATG--AHTY-PGREEDF--LAERLEERGDLPRHIVFLWPDGAA
GEGEGAEGEGDRGIHSLYALVRTLAPRLGTGPAVTVLVAWTGTGTA---GEPQPLNEALGAFARSAGLEKLPLRFKALALPGGLGE---AVWPLILAELS
EAPFEPEVRLDGGVRRVPRLRE------SA-AAAPFRQGGVYLVTGASGKLGSLVAGHLARRWGAKLVLTGRRA---PDPD--GPLAALLA----PGR-A
LYVPADLGNAGEVAALVAAARTRFG-RIDGIVHAAGLLTEEHMTARRREDVAAVLVPKIRGARLLDDATAGEPLDLFLLFSSTAAPLGNALQPDYAYANA
VLDGFAERREAQRSGRTVSVNWPLWRDGRIGAVLPA-----------------------------------LLSWLERGVAGAA----------------
---A-----A------------------------------------------E----------RPPAEDVQAELRRIASGLLKLEEIDPDTELSEYGFES
ISLIEFTNAINGRFGTELMPTVFFEHRSIASLARHLGGQ-----------
>tr|V5DH19|V5DH19_9GAMM Polyketide synthase PksL OS=Methyloglobulus morosus KoM1 GN=pksL PE=4 SV=1
---YSPAWVEEVIEVKDEMLGTGIVVVSNNDERLQFSEKNGAVPVLKVALGNGIDHQQASG-KIYINSLDAQGYSRLGGFLDEKKIDVSHIVYLWDSTHQ
ATMLELPEQTQQALTLLFHVDKSLLHATKTLKQLFVNLC-------EPNTAQWVIEGSITGFLQSIGTEYPKTTHKVVSIEAKEIERVAWDNA--LKELL
YSEKNTWVQYGQDSDSRLIWRLHGIDRFH---LSALKQGGTYLITGGMGGIAKILASYLVQNYR-NLILLGRSA---LQSEGESFIQDLKS----SSTDI
AYLEVDIGNLDRLGQAFADAKQRFG-TLNGVFHSAGVLEDNLLANKAIDSLQKVLRPKLQGTVNLDQVTQSEQLDFFLVFSSLTAILGNPGQCDYGAANG
FMDAFIAHRKKLRYGSSLTINWPFWNEGQMGQDNDVLSLLDSFGLPL-DKVEAFGCLEEALHFGGSQIAVI-------------K--------KEKEFSK
PSI--------KQKNVS--------------------------------KVP-ERSTIN-ITVDQIISRLSIDTRRLVAELGKFEQISTQSDFMALGFES
VVLAKLANMLNKKYALKISPAVFFEHTNLEKLNAYLLDE-----------
>tr|Q2T4P0|Q2T4P0_BURTA Polyketide synthase, putative OS=Burkholderia thailandensis (strain E264 / ATCC 700388 / DSM 13276 / CIP 106301) GN=BTH_II1665 
---LAPVWEIVDAAAGFS--PGIV--VADDA-------AW--------AER---------------RIVGADAFRE---VAAALG--AVDAFVWIAPRAA
RGGALADSPALDCAANCFEWIAALLAAGAANRAIDALFVTSGCADD----PGDPAHAAIAGLVGALAKEHPRWRVRIADHASAEPAPVDAL-R-----LS
PDQGDA-LAYRDGQWLRR---RL---ETMG-EPAAHRAGGVYLLIGGAGGLGVVYSEYLIRRYGAQVIWVGRRE---RDADIDAAVARLAA----LGP-P
VYRRADAADPAALRAVCDDARARFG-ALHGVVHAAMVLADRSLARMTQQTLRAALVPKIDVARSMAVLLPAADLDFMLFFSSMNAFTTQPGQGNYAAGCT
FVDAFAHALRAQ-ACAVKVVDWGFWGSAGAVATPYF-RARMEAGIGSIEAPQAMRVLERLLAGPHGQLAMIHAIRPTMTSARALECADRYRYTDV----S
AGFHSIAAAGHGQTIVCAS---------------------SDGVVADATGA-DPDADTDADADARLRDAASAWLRARIGAALDIDDIDSRETLERYGIDS
ITVLQLTKRLRDAFD-DVPNTLLFEYNTVDALVDHWLAT-----------
>tr|E9KSM3|E9KSM3_9PSED Polyketide synthase OS=Pseudomonas sp. 2663 GN=fr9F PE=4 SV=1
---LSPVWESLPAQDG-----------PSGP-------RW--------VFGSNEAVRAALEGTRTVLDGTDDAFTLKAYAETARA--EAPHLLWISGGGE
NPDLDPDALISRGILPLFRLINALIEAGLDSVPLALTVVTRRLDET----DNDISDAGVVGLVGTVAHEYPHWTVRHWDVDAPVDDGRFFRLDTHL-ITT
AGDGDV-RVHRGGRWHRQRLARV---DEGR-ADPVYREGGVYLVIGGAGGLGRTWSRHMIERFGAQIVWLGRRA---PDDEIRAHLAALSA----LGRGI
TYLQADATDAVALKRARAAIMEQFG-ALHGIVHAPIVLADRSLARMDETAFRLSYDAKLKTCANLYPLFAREPLDFVLFFSSLNAFSRSAGQGNYVAGCT
FTDAYARKLDTR-ACDVKVINWGYWGDVGIVAGARH-RERAAAGLDSISAEDGLRAIDALLARPGSQVAYVRTARPIATTDGLLRRLEPYCYTDV----S
EGLRPLGQHALGQQIIVFE---------------------SDGVVTADAS--P------TVSEEMRFNGALAFVQRLVADTLKIDELPPDEHFQSIGLDS
ILVVQLTNQLRRYFD-GITSPLLFKVSTVRALTEHLWLA-----------
>tr|A0A0Q5RHB3|A0A0Q5RHB3_9BACL Uncharacterized protein OS=Brevibacillus sp. Leaf182 GN=ASG16_06485 PE=4 SV=1
---LTYVWGEAEVETSQP--PNRTVIIAEDESVA--VREW--------PAAP-----R-------IDT------EEMAHKVRACG--EFEHLLWIAAREP
AGAAVSDAPIERGVLHLFRLVKALLALGYGSKRIALSFITQQARDD----AVRSSAASVHGLAGAIAKEYPLWAIRVADLEAGGSLSFDQ------FRLP
ADEGHV-WACRDNRWYRQQI------AAVP-KQSLYRQGGVYVVIGGAGGIGEAWTEYMIRQYRGRIVWIGRKS---LDETIQLKIDRLGA----AYGEP
WYISADAKDKQSLQQSIDEVKSRYG-TIHGVIHSAIVLLDQSLANMDEARFRAALSAKVDISARMAQVFAAEQLDFMLFFSSINSYTKPAGQSNYASGCT
FKDAYAHRLGKE-PFPVKVMNWGYWGSVGVVASEEY-RKKMSLGVASIEPDEAMAALELLLVGQLDQLVMLKMTKPVPTSAVVLKRLEPYLYTDL----S
EGFRSIFGAA----VIAAE---------------------SDGVYNRCASVPSTNG-ASDVSDRALGSFIQTVIRTAVADALQIGRIQDDRSFSDYGVDS
IIAVNLINIINEHCDTQLQTTIIFDYNSVERLSDWLLRE-----------
>tr|A0A059KPH2|A0A059KPH2_9BURK Uncharacterized protein OS=Sphaerotilus natans subsp. natans DSM 6575 GN=X805_09770 PE=4 SV=1
----------------------------------------------------------------------------ELSGMDAP-APLRGVVFVPASDDL
ADG-ETSALDTRLQRSVTLVQALSAPQAETPSDTKLWVATHRALPLTD-QPVTLVQTPLVGLGRVAALELGRHWGALVDLDAA----DNAARARALATLQ
PPDGETEVAWRQGRRHVARLERAPALAVQ---PLSLQAEALYWITGGLGALGLRLAQRLADLGARHLLLTGRRATVEAQA--QSVLDALA----ARGVSV
QVQAVDVSDAGAMGALIETLR-SGTTPLRGVFHTAGVLDDGVLLNQDWPRIARALAAKVQGAWLLHRLTADLPLDLMVSFASVAGLIGNAGQGSYAAANT
FLDGLARWRR-RRALPALSVDWGIWADAGMAMR----EVLSFPGVRPMAPERGLAALERVLSQADRQAIAELD------------------------AMA
-------------E------A--RPGARL-LATLMPAAPAVAPGANAAGHTPLRERLGAL-APARRAAAMQAWLQQTVGALLGMQPPDTTTGFTDLGMDS
LMALRLRHRLEAELGCALPSTLAFEYRHIDALAPFLLER-----------
>tr|Q3LRL4|Q3LRL4_9DELT MmxC (Fragment) OS=Cystobacter fuscus GN=mmxC PE=4 SV=1
--------------------------------------------------------------------------PEHFEQL--A-GPVRAVVHLWGADAP
PASEPTAEVEAAQQLGVRLVRALVR--GGSASGARLWLCTRGSQPVGV-ACGSPLQAPLWGLGRVIALEHPDTWGGLVDLEPG----AAAGVEALWHELS
GSDGEDQVAFRGGARYVARLVPAAPAPAA---PVALRADAAYLITGGLGGLGLHVARWMVSKGARHLVLLGRRGLPDRAEWQLAAIEALE----AQGAVV
HASSADVGDPTRMAEVLESIR-RGPAPLRGIIHAAGVSTLVPLETMDEAALASILRPKVMGGWVLHQLTRELALDFTVYFSSGSAVWGSTRMAHYAAGNQ
FLDALAHYRR-ARGLHALSINWGPWAAEGMVAEEGLRE---RMGLGGVTVEGGLQVLEALLAMDVTQSVAPV----------------------DWSLFK
-------------SVY---ES--RARRPL-LEALGPVSAPAPRPVEQAAGSEELARLRNA-SSARRKELVISWVREEVARVLGFAAVKLEQGFFETGMDS
ITAVELRRRLVARFGVQLPTTIAFDRPTVLALASYLLAD-----------
>tr|A4D934|A4D934_9NOSO CrpB OS=Nostoc sp. ATCC 53789 GN=crpB PE=4 SV=1
--------------------------------------------------------------------------EQLIQ-ANSK-LPLLHVINLWSLDIQ
GTQDLTTTLKQAQLWGLQLVKVLT----KTKSVAKLWLVTRGAQLVSQTESVCVAASPLWGMGRVISLEHPQLWGGMVDLDPI----SPESAYTLLQLLV
NNQLEDHLALRADNLYFARLVKQSL---D---SVSLKDNATYLITGGLGALGLHTARWMVQQGARHLVLTGRKQPN---LEAQQIIEELQ----KLGAQI
LVLCGDISDEVDATTIFSEIE-ASLPTLKGVINAAGVLDDALLHSMSWEQFTQVMAPKVQGAWHLHNLTQNKALDFFVCFSSMASLVGSPGQGNYAAANA
FMDALAHHRR-GMGLPGLSINWGPWAQAGMAASLDNRDRMVASGITPLTPEQGLQVLGQLLEQSLPQGVLSVQ----------------------WSVFQ
-------------EKF---SF--GNQIPL-LLELLGETESQQAFRTKTKQNELLKRLESL-PCKERYYVLRTEIQSEVAKVLALQLPGFEQGFFDLGMDS
LMAVELRNRITQLLKVTLPSTLSFDFPNIEQLTKYISSQ-----------
>tr|G2NZI8|G2NZI8_STRVO Beta-ketoacyl synthase OS=Streptomyces violaceusniger Tu 4113 GN=Strvi_3795 PE=4 SV=1
------------------------------------------------------------------------------------AADVPDAVLVPCTRTV
EDDGD---VAEAAHAALALIQRWISDE--RFASSRLVFVTRGAVAAPGEEVPDVAHGAVWGLVRSAQSEHPGRFVLVDLDGHP----ESVD---LPGA--
-ASGEPQCAVREGRARVPRLGRVAMGAGA---HRRLDPEGTVLVTGATGTLGGLLARHLVSHGVRHLLLTSRRGPAAEGM--AELRAELD----ELGAAV
TVAACDTADREALAGLLGAIP-A-AHPLTAVIHAAGVLDDGVVDALNPERLDLVLRPKVDAAWNLHELTADHDLAAFVLYSSVVATIGNAGQANYAAANA
FLDSLAQHRR-ARGLAAQSLAWGLWEQRGMSGHLADARRMARSGIRPLPSAEGMELFDAARAAGDATVPVRLDRRR--------AASGTQDAVPYLRGLV
-------------RTP---V----R------RVVRAGGGGG---AVETGESSLGRRLAAL-AAADRDPFLLDLVREHAAGVLGLEDIEATRAFREVGFDS
LTAVELRNRLGAATGLRLPTTLLFDYPTPAVLVDQLRRE-----------
>tr|S4XS92|S4XS92_SORCE Uncharacterized protein OS=Sorangium cellulosum So0157-2 GN=SCE1572_16945 PE=4 SV=1
--------------------------------------------------------------------------ARLWAELR---GPARAVIHLASLDGA
EGTDAA------LRRGLAWIQAAGEARPEPRDAPKLWLVTRGAVSVPGDRLTAPEHATLWGLGRAMSLERPALWGGLIDLPAE----IGEDVAALVSQIL
GPDGEDHVALRPSGRFVQRLVRHRGLRSR---AARWSTPGTALITGGLGALGLRVAEWLARRGVQHLVLTGRRGASTAEA--RSSIAALE----ALGAAV
TVAQADVADAGAMAAVLADID-ARLPPLSAVFHAAGVEDHTPLAALDDARLAEVLAPKVHGTLVLDALMRDRPLTAFVCFSSIASVWGSGGQAGYAAANA
FLDAWVTARR-AAGAPAFAVNWGPWQGGGMMTERGLA-ALERRGVKALGPGVALAILGRILDADAAQVVADVD----------------------WPRFR
-------------AVV---ET--GGPRPL-LAEMPRAAEA----ASGPAEAALLDELRAA-PPRERRRRMQRWLQGAVAQTLGFERVDPTRGFFDLGMDS
LMAVELRRRLHQALGLPLPSSVTFNHPNVVALAEHLLER-----------
>tr|D9W5N6|D9W5N6_9ACTN Modular polyketide synthase (Fragment) OS=Streptomyces sp. C GN=SSNG_07466 PE=4 SV=1
--------------------------------------------------------------------------ATLGDAV---GLPAPGVVVLPVGGTP
-QD-A---LADAVREELTVLQDWLADE--RLEGVRLAVVTRGAVSVPGEDVTDLVHAPLWGLVRSAQAENPGRLLLVDLDAAE----DA-PA--LPAAAA
--AGEPQAAVRGTAVLAPRLVRGTAPGGV---PQGWDPAGTVLITGGTGTLGGLVAKHLVTHGVRHLLLAGRRGPDAPGA--AELVAQIA----ELGGTA
EVVACDAADRDALTALLAAIP-A-DRPLRGVVHTAGVLDDGVIASLDAGRLAAVLRPKADAAALLHELTRDLDLTAFVLFSSAAGVIGGPAQGNYAAANA
FLDALAQHRC-AQGLPATSLAWGLWDEAGMTGHLSEEARMARSGMVAFSPAEGLALLDAGTADGTPLVPVRLDRTM--------AAG---HTLPLARGLV
-------------RVS---A----R------RTVESAD--------GAGGSALARRLTAL-SPDDQLRTLLDLVRTHAAAVLGHDAVGAEKAFKELGFDS
LTAVELRNRLGGATGLRLPATIVFDHPTPSSLARQLRTA-----------
>tr|D0LQW2|D0LQW2_HALO1 KR domain protein OS=Haliangium ochraceum (strain DSM 14365 / JCM 11303 / SMP-2) GN=Hoch_2956 PE=4 SV=1
--------------------------------------------------------------------------ASLAAAL---GAAAPAWVLVPCISRD
-TPVD---RTSETERVLARLQEWLADD--RLSALRLVFLTHGAVATPDQDVSDLVHAPLWGLVRSAQSEHPDAALVLLDSDES----EASRV--LQAAAG
EFLPDRQLALRAGRLLAPRLVRGREAD-F---ARPIDPAGTVLITGGTGTLGGLLARHLVQYGVRHLMLISRRGPGTPGV--EALAEELE----SAGAHV
QLLACDVTDRAALQHALEVVP-K-DHPLTAVIHAAGVIEDSVLSTLTPARLSSVMRAKVAGALHLHELTESVDLSTFILFSSLSGVIGSPGQANYAAANT
FLDALAQHRR-AGGLPALALAWGAWDETELTAHLTEAQRLRQMGFHPLPATTNLALFDTALAQPDAAVAARFDDKH---------RN---QTLPLFRDLA
-------------KQP---L----D------RPRANNL---------AAHMSLGERLRPL-SPGERQRILLELVQTEVASVLMLHNFDSQQPLQKQGLDS
LMAVEIRNRLGAATGLRLPATLLFDYPTPAALASFFAKQ-----------
>tr|A0A0M4KKD6|A0A0M4KKD6_9DELT Polyketide synthase OS=Nannocystis sp. MB1016 GN=ncyB PE=4 SV=1
---------------------------------------------------------------------------AGLPAA----LEAAQVLAVWDEAGD
-GAEAA------LRTATAGL-AIVQ--ATLGRAGRLWWVTRGAVAVDD-EAVAVAGAPLWGLGRTLMQEHPELRCTLIDVADG----EVD-VARLLRELA
SSDGEDQVALRSGGRHVARLVRLETASEG---RFVAPIDGTVLVTGGLGALGLHVARWLIERGTPHVLLVGRRGPATPGA--AEAVAELA----RDGARV
TVAAVDVADRAALAEVLAALP--AGLPLRGVVHAAGALEDGLVTAQTAEGLARVFAPKVAGAWNLHALTEGSGLALFVLFSSLAGTLGAAGQANYAAANA
FLDALAAHRR-SRGLPAQSLAWGPWAESGMAAELGAGDRLARQGFASLAPAQGLGLLASALARPEALGLAEIDA-R--------ATG---TVPPVWRALV
-------------TGE---AV--GKSRPS-RAAAEEL----------PTAQGWQERLSGL-STARRLERVRSAIQAEVGRVLSSGAVAIDRPLQELGLDS
LMAVELRNALAQRFGVRLPATLVFDAPTVARLAERVLAA-----------
>tr|A0A0Q2MA37|A0A0Q2MA37_MYCGO Polyketide synthase OS=Mycobacterium gordonae GN=AO501_21650 PE=4 SV=1
--------------------------------------------------------------------------EQRLEAVAAADEPSLRIVVLSAVESD
TTPSMR-----LLRMQLGGARRLFRAAAAAEIRNPIWLVTSGAQRVAT-DAVSPVQSCLWGFGRSASLEHPQLWGGLADLSSG----SADE-SRLIDAAG
AGATEDQVALRDQAVYVPRLVRRAGAPVT---PLSLRGDATYLVTGGLGAVGLEIAGYLAAHGAGHLVLTGRRAPNSDT---QQRIEARQ----QTGAEI
RTVAADVANPHDVDRLIATVA-AELPPLAGIVHAAGEIGSTPLRSLDDAEVDRVFAGKVWGAWNLSEATADVPLDFFLSTSSIASVWGSFGQTAYSAANA
FLDGLSSRKR-EE--NYLSVNFGPWMSGGMADEE---AQLKKRGVVTMAPGDALAGMAELIVTHSVQVVARID----------------------WERFL
-------------PIY---QQ--TGRRAF-LGELEREIPESATAPTASGTTKLVERLTVA-PVQQRKKLVVDYLREVVAEVTRVAEIRDEAGFFDLGMDS
LMAVELRRRVEHGVGKALPATLAMDYPRLVDVADYLLTD-----------
>tr|I0J6Y3|I0J6Y3_SORCE Polyketide synthase OS=Sorangium cellulosum GN=pelD PE=4 SV=1
--------------------------------------------------------------------------RDGVEQA--V-ASIAGVVCLWGEAPS
PGPGASSVVDEAERTSLGVIQALVG----RGATSQLWFVTQGAQAVPG-ETASVSQAPPWGLGRVAMVEHPELECRLVDLAPG----AEDGLEALWQELC
CPDDERQIARRAGKRLGLRLSAAPPAAGP---ALAAAAEGTVLITGGLGALGLRVAWWLWEHRAGHLLLVGRSAP----EGRLAEIERLR----AAGAAV
TVAQADVGEARDVQRLLASIP--AERPLRGVVHAAGVLDDGVLVEQSAARIGTVFRPKARGAWNLHTLTQGTPLGFFVLFSSLSSVLGSGGQGNYAAANA
FLDALAHARR-ASGLAGQSLNWGAWADGGLASALSAAARSSRAGFGMLTPAQGLSLLGQALGRPEAEVPVALDERS--------FSG---EVPPLWRGLI
-------------AAK---PE--RG-RGL-AKG------------------AWAERLGAL-DASARAAEVASALRADIARVLSFNEVPEERPLQELGLDS
LMAVELRNAIAARAGKPLPATLLFDYPTLRDLKRYLLER-----------
>tr|F1T739|F1T739_9FIRM KR domain protein OS=[Clostridium] papyrosolvens DSM 2782 GN=Cpap_3719 PE=4 SV=1
-----------------------KFVILDNTHLYDSIKQ---LGLDAVLVRPGNAKNKISQTEYEICSCEEQDYKWLFQNAVNNSS-STCIIYNINYAEE
----FFVFVKAVVSSGLRSNIKLFHVFSG----D-------IQSANKLSVNP--MYLACAGLLKTAVMEMPKL-----VCKNIAFDKSIVKLAGYLRDEL
ALGNVEIYYSFEDKRHIRALKELTGTN---PQQSTLKVNGVYYIIGGLKGIGLKFAEYLATTYKANLIISGRTELSAE------NKKHIENL-QRVCESV
LYLQADVNVYQDMKNSVELIRNTYG-RLDGIVYSAGIKQDELIINKTPETFTRIIETKTLGIQNTCKAVGEEPVDFIITFSSLAGLMGNMGQADYAYANN
YLDAYATVEG-FNGKNMLSINWPYWLDGGMRLDSEIEGMKRRNNMVPLQTKDGLQAFEFAISNLSSV-----------HQLFVLASDNVTKSQ-------
-------------EV--KTVKEDSSKS---KEPSGKKSVETKG--V------------------SASESAISYLKNVISEETEANRIKNNEAFDAYGLDS
VMIMNITVSMEKEFG-ELPKTLLYENHNINELNEYLQTN-----------
>tr|A0A0A1FDT8|A0A0A1FDT8_9BURK Malonyl CoA-acyl carrier protein transacylase OS=Collimonas arenae GN=LT85_1869 PE=4 SV=1
-----------------------VLVIADDTSLAETLALRFASSVNVVLAQSGAAFSRLGERRYCFDPANPHSYTELLTHLASQDLRPSHITHYTAVD--
------HDDVQSLRRGMLSMRHLFNALEQ----T-------MPREAIQPQHD--AISGYARSLLTI---N--H-----RFELFTVRAERSLAAMLQNEFE
ASGAGLIAL-WNGRRYLRSLAPLG-MS---QNALPLKSRGVYLITGGAGKLGLVLARYLATHYQARLILSGRSERLHDE-----ALAQIEAL-RAAGADV
HYHCSDIAQAGQADALLAVAKQVYG-RLDGILHCAGVASDKLITELDEVAFAELLAPKIDGLLALDRATRSEPLDFFVNFSSVSAMLGDLGSGAYAVANR
FMDSYAVWRG-QCFGKSLSIGWPLWATGGMKIAEDASLF-SFSGMSALTEAEGIEAFERLLRGDM-------------QQVLL-AVGDAAKIGRALRVHV
EQAKTVSAARTTSDSNTAL-------------PSG---ASSDGL-S------------------DQQRRAEHYLKERLGIVVAASDIGGHTTFEQLGMDS
VMLMELRNSLTQDFP-GLPKTALFEYDTPARLAQYLMQQ-----------
>tr|C5BIL8|C5BIL8_TERTT Modular polyketide synthase, type I PKS OS=Teredinibacter turnerae (strain ATCC 39867 / T7901) GN=TERTU_1990 PE=4 SV=1
-----------------------LLSVGFEAGQAGELTSA-Y---SGTFT--HLAFSGITEQDNWFAACDEESITDVLNQLENYRGLPTAILFN------
-------ESDDSVQAPLLRLALLIQVLEK----V-------HPNDVATCIGE--AAAGFAKSLLSV---N--H-----RFRLVTVGAETDQPSLFYIQEA
GYTNADVQY-LQGERRVRRLYSASPSS---QRNLPLEQGGCYLITGGLGKLGLLFARYLAKHYGANIVLTGRSAM-NDN-----ALKSLVEL-QQLGASA
TYFPADISDPHATKRLVDHCVKTYG-KLDGVIHSAGVADSKNLLQQSMSDFARIMEPKIAGTIALDQATAGESLKFFVVFSSISALVGDLGSGSYACANR
FLDAYIALR---ASDRGLSINWPLWNEGGMEIEEQRAFF-DFSGIQPLDEQQGLEAFESMLSLPH-------------ANLLV-ASGEIQKLQQYLRVAD
ALPTLISTDREPAAAMLLTAPADNPKP---QIATP----DGASMSG------------------SPGSALFDFLRDHVVTVTAVEKVDNHTRFEGFGMDS
VMLMELQNNLQKQFN-KLPKTVLFEHDTLAKLAEFLEKN-----------
>tr|A0A0J6G723|A0A0J6G723_9XANT Uncharacterized protein OS=Xanthomonas axonopodis pv. phaseoli GN=ACP93_01060 PE=4 SV=1
-----------------------VLVVADDLDLAQGLVRALPDGDRGI----AVAFAANGDASDRFDPFSAASGSALFDSLRDRDLLPERIVILWSAG--
------DTGTSVLHRGLQSVRQLFVASER----V-------NPDGGVHPQHE--AIIGYARSLLMA---N--H-----RFELSTLSDDRDRARAIVDELD
VDGGANIAW-RGGRRHRRTLRALAHDA---NAALPLRDGGAYLITGGAGKLGLAVAQWLATKCRAQLLLCGRSAEVPAS-----AHDALDTI-RALGTQV
EYRSVDIADAAAIAAFVAVAEREFG-GLSGVIHCAGSASDRSILELDDAGFNALLAPKVDGLIALDRATASLPLDFFVAFSSVSALIGDLGSGAYAAANR
FMDGYALWRG-LRHGRSLSIGWPLWATGGMEIGGDSVVF-GYSGMQALSEAEGLEILGTLLRSAQ-------------GRVLV-TVGDPKRIAKTLRLAE
GGERIIDAKPVMHDVAIAAPPTVHSEP---QVPPAKYSAVAHTVDD------------------ALGSEVEHLIKQRMAAVTQASAIGSRTSFEQCGMDS
VLMLELHTALRADFT-ELPKTALFEYDSAAQLAHYLLAR-----------
>tr|F1T739|F1T739_9FIRM KR domain protein OS=[Clostridium] papyrosolvens DSM 2782 GN=Cpap_3719 PE=4 SV=1
---CIETWEEQELHKTGTNTEQQEALVFCHK-------DFTK---ERVFKSLGENIIQIHPG---NEFRQINPYELELN-LSDESSYMKLYDWLTSN---
----------HIEIRLAINCFCLCENKIL-DENVSTFSVDFFFHVLRPVWNATC--AATSAFFRVLSNENSRICCHSIELSSI----NELCLELINDER-
-TSKNLEVKYVSEKRYIKKLELTELIDDN---AKFTVWEGNYVIIGGLGGLGTLLASHLITEYNAKVIVCGRNCNYDLIEE------AKAEIR-KKGGDL
VFHSCDITSEESTKKFISQI--AEQGKINGIIHCAATSKDSMIIKKEKQDFDYVINPKVNSIKQVELIAKECRDYILY-FSSIAAYVGTVGQCDYAYGNS
FLNNYVSEQK-NLNVRLISIAWPLWESKGMNASKLVKNNMQKQGFDVLSREQGIKVFETVLNSGKSGTFITFYGKKREIIDLLGLKQEGNERGS------
--------------------------------------------S------------------FMNKEKINLFLKESIASITKHTDIDDYEYFENLGIDS
IKMINIIAKMEEKLGS-LPKTLFFEYERLDQLEEFVEKE-----------
>tr|L8PZ48|L8PZ48_BACIU Polyketide synthase type I OS=Bacillus subtilis subsp. inaquosorum KCTC 13429 GN=BSI_21430 PE=4 SV=1
---YAPVWKESPLPEVLTDGQRCTLLFSDHKRYSEREN----------TFTKGDRFEQISDDVFTINRENPEDYISLIRLLKQKNAIPDSILHAWADKQS
-------EFDEALQTGIYSVFYLTKALIS-ENLINKVR---------EKRLPCF--EGIGGFFKSVKQEYPELCCKAIRFTNG----SLYESDIYKEIDA
APDHNINIMYKDGVRYAQVLEKKTKTFSP---VQYPGKDKVYLITGGLGGIGSKIAEYCAKS-TCTIILSGRSPLRGK----------LEYLN-QFNAEV
FYMQADISDKETVIKMVDDIM-ERYSGLSGIIHCAGVIRDSFLFQKTNQELSEVIAPKVQGTLYLDNATKEIDDFFAV-FSSVVSIAGNEGQTDYAYANS
FLDHF-RQKS-QRNGRTLTINWPLWKETGMGVSIQARTSLFDSGLEELSSEAGADWFAQIVMSGQLHNIAVC-GDSDRFEQFMEQRFQTNYTQI------
---------------------------------------------SDTI----------QLASGDVKIQTRSFLASIISAEVGVEEIDHSVHLAEYGMDS
VMIHQCNSKLEQALGA-ISKTLLFEFQTITDLADYLIKE-----------
>tr|A0A0Q6T6W1|A0A0Q6T6W1_9BURK Uncharacterized protein OS=Massilia sp. Root335 GN=ASC93_12730 PE=4 SV=1
---AAPQWEAAALAQGGPQ-------------------AWAQ---RHVLVAVGADVAALQAASAGARCVRLPGA--------A--------------GGD
--------LADYYRDAASACFLHVQALLA-ARPQGRTLVQLVLA---TPADELL--LGLVGLLKTAALENPLLAAQVIVLDAA----AQAARQLETEAA-
-GAQAGVVRHVQGERQVLAWRELDM-EEP---APAFKDGGVYLITGGTGALGGLFARAILDRAGATVVLTGRAAAYAP-----------ADLP-AHTGQV
HYRQLDLCDADQVRALVAGVV-AQHGRLDGILHAAGMTGDGFILKKTAAEFEQVLAPKVAGTVNLDAATQDVADFLML-FSGGAAVTGNAGQADYAAANG
FMDRF-VRQG-RRQGRTRAVNWPLWEDGGMGADAATQAQLKAAGLVPMRSRTGLRAFDHSLALAHDQVQVVE-GDLRLVRAALFAPEPAAEASA------
--------------------------------------------PQPATVN------GGQAGGADLRARTESFLKKRLSSLLKLNRIDAAAPFEKYGINS
IMTMDLTGELETIFGA-LPKTLFFEYQTLSELAGYFVAQ-----------
>tr|A0A0A1FDT8|A0A0A1FDT8_9BURK Malonyl CoA-acyl carrier protein transacylase OS=Collimonas arenae GN=LT85_1869 PE=4 SV=1
---YTPVWTTQPIAGATSEGAIEHLLMGDPSDVSWATSQFAS---TRIEH--GSEAAVEDAGALHVRPGRLEDYEAAVAALVAKGGKLDHVLLIAPRLTS
DIAQASDSLDSQVCKSAQNLFSLVKAMMR-GTK-RAKFLHLVSRQPQ---RPEY--QGLSGLYKTLRIEKPSYSGRVVQCDLA----EQRLAELVFKEFN
TADKYVDVSYSGDVRSVRKFRQLDANADL---TASLRKEGVYLITGGMGALGLIFARYLCERYQATVFLTGRSAPTEQ----------LNELS-SLGGHA
SFLTCDVVNRDDVRRAVDSIH-AAGHQLNGVIHSAGVIEDDFILRKSPESFARVVAPKTLGTWHLDVETRDEPDFFAL-FSSVTGVLGNIGQCDYGFGNA
FEDYF-RRQG-SRNGKTLSVNWPYWKEGGMRLSDKEEENLHSFGLVPLLSGQGIEIFEYALTRLHSQLVVMP-GDAAKVQEVLGVVAVPVPVAA------
--------------------------------------------VVAAALPAKIAHSQPLLTTGDRSAAVSRYLAELFAAQLQI-DFELGRSFREYGFDS
IVMIDLVNLMEKKFGS-LPKTLFFEHQTLGELTAFFIEH-----------
>tr|C5BIL8|C5BIL8_TERTT Modular polyketide synthase, type I PKS OS=Teredinibacter turnerae (strain ATCC 39867 / T7901) GN=TERTU_1990 PE=4 SV=1
---YAPYWDLVDTPSVNADKS--VLLVAEHAECETESSLFDG---VRWAS--GADFATLPNNHFTAQGTQLDQLEQVFASLKAQSLLPERVLFLHHVTAV
SDF--SAASLNDATLLAETLFCVVKAAFK-PVR-KLRFVSVAAGN--RDGSPLV--QGLSGFYKTIRLEKPTYSGRTVLLESL----DKSIQQQIVNELY
VDDQRVDLAYAQNQRFAREFYRFNEYEPS---HIGFKKGGAYIITGGLGALGLLVAGYLLETYSAKVYLTGRSPLKDG----------LREKC-TDGAEV
SYLQGDAADFDAVCRWVESIN-ADGHGVNGIIHSAGVIEDNFIIKKSLDAFQRVLGPKVRGTLALDLATKDQPDVFVL-FSSVTGIFGNLGQCDYGYGNA
FEDCF-SVNG-ERSGIAVSLNWPYWKDGGMQLGEKEEEILFNFGITPLSNPSGLAALDFAVTNAIPQMAVLE-GDQSRVCEVLGVKNAHQSAIA------
--------------------------------------------TTQAKTV------SGAQGT-ASKEDVFGFLRKVFAAELKLDRFDLNSSFQAFGFDS
VVMIDMVNALEKTFAG-LPRTLFFEYQNLNDLSDFILAE-----------
>tr|A0A0J6G723|A0A0J6G723_9XANT Uncharacterized protein OS=Xanthomonas axonopodis pv. phaseoli GN=ACP93_01060 PE=4 SV=1
---YAPLWVRAAIPSAAQAPA--MVMIGEREDLDSRSPRFAG---TSFERAAGAGLAPE-EQGNALRAGSLADAEAAIGAWKARGAQLEYFVWVAPKPSE
N-----LSVQARIDAGARTVFALVKAMLR-GPK-RARFVHLNHWDIDGLGATDV--IALAGFYKTLAIEKPSFSGRVVQCPTD----S--WADLVADELL
ADDKVTDVRYRNGLRETRRFASVHSST-G---STDFRTEGAYLITGGLGALGLIVARHLCERYRATVYLTGRKPLSEA----------LEALA-GLGGRA
MYFACDITDRDAVRQVFATIRRQHDQVLNGVLHSAGVIEDDFLLRKPAEAFARVIAPKTLGVWCLDQETQHDPDLFVL-FSSVTGVLGNVGQSDYAFGNA
FEDAF-VADG-QRSGKSVSINWPYWQDGGMRLGEKEEEALQSFGIVPLTTQRGIEVLDYAIAQAQPQVVVMPAGDIHKVREVLGVIAEDRQPAA------
--------------------------------------------PSIAIAASPG-EGHADDAPSNWHALTSSFLANLFASQLGI-DFEPERSFKEYGFDS
VVMIDLIADLEKSFGT-LPKTLFFEYQTLGELSGYFIEH-----------
>tr|A0A0J1EY99|A0A0J1EY99_9BACL Uncharacterized protein OS=Paenibacillus sp. VT-400 GN=EL84_29080 PE=4 SV=1
------------------------------------------------------------------------DYIQLLDDM--KGQGLTRIIHGFTLAEN
DSDDYLEQLKLSQDRGIQSAFYLTRAILHVTEGLQLQFISSLANAVYESQV-RPENATLNGFAKVIEQEYPEISCRFIDVDSD------TDADTIYAELN
SSHDRFQVAYRHNQSYVEELDIANILEAS-HEEVTIRENGLYLIAGGTGGIGLQFAKHLADERSIRLALISRTAMPDWDKEMIERMKTIMELE-AGGSSV
ELISADISDLEQMTQVVQGLRTKYG-QIHGVINSAGVANDGLIIRKEETAFQEVLRPKVQGTWVLNQVTAQEPLDFFVMFSSGISMLGEPGQSDYVAANC
FLDSFASY-RANGSGRTLTINWPAWKETGMAARFGLN--VD-TAFKTLATHQAISAFDMVLSRRIRRVLIGE-----PNYASE-L--LPLLESSRVIQFS
----------------EAMTARIQQER-NHLNYHNQLTRTEY---------EQKVELHGRD--NGIYTTTEKELAQLVGHVLGFTGLDVYDNLFELGVDS
ISMMRIITEIRVRYHVHLNYHTFFEGMNLAKLAIHLIGALKET-------
>tr|A0A0F6EWS4|A0A0F6EWS4_PAEPO Uncharacterized protein OS=Paenibacillus polymyxa GN=LK13_18685 PE=4 SV=1
------------------------------------------------------------------------SYLRLILDA--EGQVLVEIKRGASFAKL
SDHAYFDHIHLLSGQSMVQLFHLAKAITQKPAVQELTVIAEQAYQVLENEL-QPEHAGLFGLARVIGQEYPDLTCRCLDIDTN------TRISDITHSLW
GNDDTFLTAWRNGERYVEQIEPVDLMESK-ADPITIRPQGVYVITGGTGGLGLAVGQWLATKGKVTLGLLGRTQLPPWETRMLNTITALLELE-RQGAQV
EYYAVDVADEAAMKQAMNEFRHKYG-AVHGIIHAAGVAGDGYMALKSQDRFNEVLAPKITGTHVLDRITASDTLDFFILFSSVTSLTGGPGQSDYTAANA
YLDAFAEW-RNQSGHRTLSINWAPWQETGMAFEHKVD--FQESLFHALSTQEGLAALEQLLLHPVSRVIVGG-----LHYAQV-A--A-LDSTAIPFGLS
----------------HEMRAILERHR-RLLHNHAVMSSDAV---------RRPVQLHGRG--TGEYSSSEKVIASIWADVLGLDELNIYDSFYELGGDS
LIASKMVGQMNQSLSTKVDISDIFNYMTVHELALYTDGEAKQP-------
>tr|A0A0K2FFT1|A0A0K2FFT1_9BACL Uncharacterized protein OS=Paenibacillus peoriae GN=ABE82_05825 PE=4 SV=1
------------------------------------------------------------------------SYLRLILGA--EGQVLVEIKRGVTFTKM
SDHAYFDHRRLLNGQSMVQLFHLAKAIAEKSAVKELTVIAEQAYKVLENEL-KPEHAGLFGLARVIGQEYPDLSCRCLDIDTS------TQPSGLIHSLR
-DDDTFLVAWRNGERYVEQIEPVDLTESE-VDPITIRPQGTYVITGGTGGLGLAIGKWLASKGQVTLGLIGRKPLPPWEARMQNTVTALLELE-QQGAQV
EYYAVDVADETAMKQALNELRHKYG-AIHGIIHAAGVAGDGFMALKSQDRFTEVLAPKVTGTHVLDRITTADTLDFFILFSSVTSLMGGPGQSDYTAANA
YLDAFAEW-RNHSGRRTLAINWAPWQEVGMAFEHEVD--FQESLFQALSTQEGLAALEQLLLHPVPRVIVGG-----LNYAQV-A--A-LDSAAIPFGFS
----------------HEMRAILDRHR-RLLHDHAVTSSAAV---------RRPVQLRGRA--TEQYSSSEKVIASIWAEVLGLDELNIYDSFYELGGDS
LIASKMVGQMNQSLSKKVDMSDIFNYMTVSELALYTDGEAKQP-------
>tr|A0A099KPM6|A0A099KPM6_COLPS Amino acid adenylation domain protein OS=Colwellia psychrerythraea GN=GAB14E_3044 PE=4 SV=1
SWLYDINWLAQPKQVSEEIDSQQWLILADDAGIGQAVAQSLIAKQPCCLVSVGEYFDYDEQNHAWLVPDSKDHFLQLFDTLGKD--NIRGVVHCWNLDTP
DDSLDIGQIQRAKRLAIHSALNLTKAINTANVKFPLYFITRDASQAPATNKANVLSGSLTGFCRVLQNFGRLI-----DVDGINDV--------IVTELN
ADSTEHEVAYRDNEAFVPRLEQAQLQTPF---PTVLKSDAAYIITGALGSIGQLVCQLLIDRGAKSLILVGRSKFPSLTPDSYERILFIRS-LEKQNINI
TLWNADITRERDLKRCLNEYAQKDSPIIRGLFFCAGVVKDTLLDKMDTAAFDAVFDTKALGAVMLHRALSKTQDFVLFSSVAAQVTTAGQT--NYATGNA
FLDSLAHARR-QDDLPALSINWGPW-AIGMIKELNADHYKNQRGMNCIQPFSGMAVLDRIIDLDNAQ-------------LMVC-DADWSVVTNWYE---
-------------G-KPSLFSHLS--------QKKSGSQ----NDKKQAFGPLYQQ-----TEVVQQVLVADHFASAVSHVLRCKQVELDLSLGNLGIDS
IMATELRNKITTHFGETLTIVRLLSGATVNELSAELN-------------
>tr|A0A0F4PB90|A0A0F4PB90_PSEO7 Polyketide synthase OS=Pseudoalteromonas piscicida GN=TW75_01380 PE=4 SV=1
SWLYQVNWLAEPEQEIQTDTLGRWVLLADQSGTAEQVADRLAKGHSSCIVKSGEYFDIDDHCHAWLVPDSRDHLSQLIETLGKQ--EIRGVVHCFSLDNS
AESLTLAQLQREKRQSLHSLLNLAKTVVEQDCKFPLYVVTRNASLVNSEQLTAVMSASLTGFSRVLDNWGGLI-----DVDGQNDA--------ITARLL
SDRQEGEVAFRENQAYVARLELATLQPAF---PTRVQSHKAQLITGAFGSIGQLVCQLLVDRGARNLILLGRSQLPELTSTNYERVRFIQH-LESQGVNV
SLWQTDLTRERELHATLESYHLSAQAPINGLFFCAGIVNDTLLGNMDTRAFDGVFDTKAIGALMLHKALSKVDEFVLFSSVAAQVTTAGQT--NYASGNA
FLDALAHYRR-NQGLPALSINWGPW-AIGMIEELGAEHYKNQRGMNCISPSAGMAVLERILDQEQPQ-------------LLVC-DADWSKVTNWYA---
-------------G-KPSLFSHLA--------TQKNDKQ----SHQEQEFAPLYQQ-----TDSALLPLVADHLANAVSQVLRCKQVELDLSLGNLGIDS
IMATELRNKITTHFGETLTIVRLLSGASINELSIELN-------------
>tr|I9NJT0|I9NJT0_9FIRM Amino acid adenylation domain protein OS=Pelosinus fermentans JBW45 GN=JBW_00295 PE=4 SV=1
NWLYDVQWQEQERSIVGGKDNSGWLIFADKQGVAEELLGLLKQGEYCCLVYPGDGITINSNSLATVASDTDGEVSSLIKTIFKDNRKCKGIVHLWNLEAP
SESMELADIEKIKKLGCYSILQIARAIGDLEIPAKLWIVTRRAQVVGEDTGDCAAASPVWGVGRVLGNWGGLI-----DLDSVASP-LKQDALNVFNEMI
SGDKEDLIAFRGEKRYVPRLHYASLTKPL---PTRFRSDGCYFITGAFGALGQLVARTMVKHGARRLILMGRTKIPTVQPGNAEKIAFIKE-LESLGADV
LLASVDITNELQVAEYFKQFKEMGYPPIRGIIHSAGTVNDKFVSKMDAKTFDSVYDPKVYGSFLLHKYLKDEPEFVLFSSVADLVTTAGQT--NYAAGNA
FLDALAHHRR-ANGLPALSINWGPW-ATGMVKELDIEHYRLRRGMNCILPEVGMNILDRVIGQDVSQ-------------IMVC-EVDWPLALPWYP---
-------------S-EPPLFAHLA--------KKEDNKN----DGDNVSFEILFKN-----ADEAFKVIVEEQLTELIAKVLRCKQVEPNSSLNALGIDS
IMATELRNKIAFHFGHSLTIVKLLSGSTIMQLAEALL-------------
>tr|H0BKQ6|H0BKQ6_9ACTN Putative NRPS-type-I PKS fusion protein OS=Streptomyces sp. W007 GN=SPW_5844 PE=4 SV=1
SWLAEPVWTDCPPLAAGAARGHDWLVLADTGGVADAFAALAAAGERCRLVRRGAAYTASDGATFTVDPGSDSDLRRLLADLDRDGPFRGAVLHLWNLDAP
AAACDRTSLADHTGAGAYSLIALARLLLARGVGGRLHIVTRGAQPALPGEGPEPLGAPAWGIGRVLEHPGKLI-----DLDPRRQPGDRAEAEALLGEVL
SD-DEEEIALRDGGRRTSRLRPAELTRPL---PLRLRTDGSYLVTGAFGALGRLLCRTLVRRGARRIILVGRTPVPGTDPAEGRAVALLRE-LEALGAQP
VLATLDITDEDALAGWLDAHRHSGAPPVRGVFHLAGQVRDTLVADLDRAAFDAVHDPKTVGAHLLHRHLRDEPEFVLFASIASLLTTAGQT--NYAAGNA
FLDALAHHRR-AQGLPALSLDWGPW-ATGMIEELGVDHYLHSRGMSSLSPDAGMAVLERVIAQDHAQ-------------LVVATVVDWPVFLAWYP---
-------------S-PPQLVVDLA--------AAAAPPA-D--AASGNGFLDAFGA-----ADEETRALVAERFAALAATVLRTGRIDPATGLGELGLDS
LLAMELRARIHAELGVALPVVALLSGTPAGELAAQLH-------------
>tr|C3HA41|C3HA41_BACTU Beta-ketoacyl synthase OS=Bacillus thuringiensis serovar huazhongensis BGSC 4BD1 GN=bthur0011_53580 PE=4 SV=1
------------------------------------AKQLRVDGKSVIEVELGKQFSKISNWKYTI-RGEQEDYDKLFEAIENENIN--QIIHLMTINNE
TDEE-LLQLQKKLSIGLESLFYLTKSIMKNTNSMELLLFTDFAHRVNGEEFIKPHNAAFFGFGKVIEKEYPKLSVRCIDIDDK------ICVEDCITEIN
SKKQVELVAYRDKDKYVQELQNVDIKALPEE-KVEFKKDGVYVITGGMGGIGLEMAKYISSKENVNLILIGRSGLSATASEIAYKI-KTINEIQESGSRV
ECYKANVANEHEIKEVFREIR-KKFNKIDGVIHGAGVSGEGFIFRKEKEVFDNVIKPKIHGTWIMNQLTKDDQLDFFIMFSSITSLGGSMGQADYAAANA
YMDSFEEFRSLVVEQKTLTINWCGWNDVGMLAEYIDEEHKDNNGFKTINSIEAIYTFDEIIQKEISKVIIG---------EIDYKVLGVHKGLI---KFL
----------ISSDILQRIDQTVSKE-----------KISEEMNFVRVNH---ID-----------YNSIENKILKVWIKVLGLEQIGIDDKFYDLGGDS
ISAIYLMKEIEKEFPSRIDVSDIFTYPSIREMALYIESE-----------
>tr|A0A0K6KWP1|A0A0K6KWP1_BACAM Polyketide synthase PksN OS=Bacillus amyloliquefaciens GN=pksN_1 PE=4 SV=1
------------------------------------IRRLELEGKTVIVAEQGDYFSQIGSHHYTV-SDSQEDYDCLVKALQSEKVS--QIVHLMSISNE
KDKN-IYQLQKKISSGVDSLFYLTKSLVENTNNIELMLFADLAHQVSGEEPINPHNAAFFGFGKVIEKEYSRVSVRCIDLDQN------LMAESILFEIN
SKKQSELVAYRDRRKYVQELQTEDLSVIREG-KISIRKNGVYVITGGMGGLGLEMAKYLSSKENVQLILIGRSEQQINMEKNNKKI-DALKEIKESGSKV
DYYKADVANESEMIHVFEEIK-SKYNTIHGVIHSAGVSGDGFIFRKKKKVFDNVLRPKVNGTWILNELTKHEHLDFFIMFSSITALAGSMGQADYTAANA
YLDSFAERRQRRRDEKTVTINWCGWSDVGMLAEYIENEHKDENGFKTITSTEAIRAFDEVMQKDIRNVIIG---------EIDHRVLELNQDQI---HFR
----------LSPDILTFKEQAIVKK-----------SVESK----TDQT---FS-----------FSDIENKLMKTWIKVLGLEQISITDKFYDLGGDS
ISAIYLVKEIEKEWPSLIDVSDIFTYPSIKEMSTYLESH-----------
>tr|W4B2Z6|W4B2Z6_9BACL Beta-ketoacyl synthase family protein,phosphopantetheine-containing protein OS=Paenibacillus sp. FSL R7-269 GN=C162_28829 PE=4 
------------------------------------IESLRREGRRVIEAVPGQGFSELDAQKYSI-GGQQEDYDKLLDAIKSQRMS--QIAHLMAIHDQ
ADDD-LQNLESNLKLGLDSLFHLSKSIVKYTYPVELLLFTDRAYRINGSETVHPHQAALLGLGKVLGKESAKLNVRCIDIDKG------TSSADCICEIK
ANKQVELVGYRAGVPYVQELQAVHLPALPDQ-EVEIKRDGVYMITGGLGGLGLEVAKYLTSLEKVNLILIGRSGLSDREDSNQYKT-MVLNQIKANGSNI
AFYKVDVADITDMQSVLVQVR-QRYGRINGIIHCAGVAGEGFIFNKEKEVFGRVTRPKIQGTWILDKLTAEDRLDFMVMFSSINSLNGSMGQADYTAANA
YLDSYSEYRKLSKGHKTLTINWCGWKDIGMLVDYKDQEEQNEQGFKNIGTQEAIDALDAVLNKDISNVIIG---------ELDHKVLGLHKDQI---AFS
----------ISPEITAIIEKFLPKT-----------PRQAAGSPAGMEF---KD-----------YSRIEDAVVKAWVKVLGLEEINVADKFYDLGGDS
ISAIYLVKEISQVFPSLIDISDLFTYPSITEMSHYIHSR-----------
>tr|A0A0E4CZ51|A0A0E4CZ51_9BACL Beta-ketoacyl synthase OS=Paenibacillus riograndensis SBR5 GN=PRIO_5824 PE=4 SV=1
------------------------------------IASLRQAGKKVIEAIPGQAFSERGEQAYSL-GGRQEDYDKLFAAIELQKIS--QIIHLMTIQDH
SEGG-HQQLEYNLKLGLDSLFYLSQSIMKHPDPVELVLFAEHVHRISGSETVNPHHAAFFGLGKVLGKEYSKLNVRCIDIDGE------TRAAECIREIN
GEKQVELVGYREGRPYVQELQAVPVPALPDQ-QAEIKKDGVYIITGGLGGLGLEVARYLSSLAKVNLILVGRSGLSHPIDPNHTRT-EIMNHIRANGSNV
DCYQADVADEREMQAMLAQLR-QRYTSINGIFHCAGVAGEGFIFRKDKAAFDRVTRPKIQGTRILDKLTAEDKLDFFVMFSSITSLSGSMGQADYTAANA
YLDSYAEYRSLIKEQKTLTINWCGWKDTGMLADYRNEENQNEQGFKNIGTREAIEALNVVLNKEISKVIIG---------ELDDKVFGLYKDQI---TFS
----------LAPEIAARIRPTRPKA-----------PGHTGLPPVPMEH---RD-----------YSGIESAIVKAWVKVLGLEQININDKFYDLGGDS
ISAIYLVKEIGKVFPSLIDISDIFTYPSISEMSDYIQSL-----------
>tr|A0A0M2GBF3|A0A0M2GBF3_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces variegatus GN=UK15_38285 PE=4 SV=1
-----------------------------------------------------------------------GAYPDLAALAEAVGAPVPETVLSRTPERT
GAEG-PQP-PDAVHTAAHDALNLAQSWLA-DPRLATARLVVVTRAAHPDSVPDLAGAAVWGLIRSAQTENPDRFV-LLDLDDREPS------WRALP-AA
LAAGEPQLALRDGTAHAARLTRVTASPPDTGTGLAARPGGTVLITGGTGALGSLVARHLVTAGVRDLLLTSRRGPAADG--AAELAAEL----TGLGARV
TVAACDTSDREALAALLAGI--PEEHPLTAVVHAAGVLDDGVIGSLTPERVDRVLRPKVDAAWHLHTLTRDLELSAFVLFSSAAGVFGGPGQGNYAAANA
YLDALAHHRR-AHGLAATSLAWGLWADETMADTIVDIRRMTRSGMTGLSAQEGLALLDLADTLDEALVPTRLDLAP-----------------------G
---GAGAVPPLLRDLVRGRARRT---------------AQEQTDTDGTALRDRLL---G-----VPAQDRARVLLDVRGQVADVDAVEPDQAFSELGFDS
LTAVELRNRLNQVTGLRLTATVVFDHPNPNRLADQLLAD-----------
>tr|B2J540|B2J540_NOSP7 Beta-ketoacyl synthase OS=Nostoc punctiforme (strain ATCC 29133 / PCC 73102) GN=Npun_R2081 PE=4 SV=1
-----------------------------------------------------------------------EDFSRLLTSQSAI----NKVVHLWGLDAP
NADVLVEGIKTATHNGCGSILHLIQAILQ-AEASQLPRLWLVTEAIANQPLPGIAQSPLWGMGKVISLEHPEAWGGMIDLEPGLASEKASIL-Q-----L
ESDGEDHIVFRQQQRYVARLVRSQHPE------LKFQADGSYLITGGLGFLGLKLAQWMVEQGAKEIILAGRRGLPPRQQRKVKAIQAL----EAKGAKV
TILVVDVCDLVQMSLALKQVH-TIHSPLRGIIHAAGVTPGYQLQNLDSKTLEAVLYPKTVGTWVLHCLTQEIKLDFFVCFSSAGSVWGAKGQGDYDAANH
FLDTFAHYRR-SIGLPALSVNWALIGSGGMVNAER---WLSRIGIEEFPAEAGFNALGFLLAANVTQVVAKVDWGKFKA------------------VY-
---EANKQRRLLLDIEVASEN-----------------EPEEATVKQPEILEKLK---T-----AQECDRHDLLVALQSEVAQVHLPDPQQGFFNMGMDS
LITLELRNRLAASLNCTLPSTLAFEFPTINDLVAYLSTE-----------
>tr|B2J539|B2J539_NOSP7 Beta-ketoacyl synthase OS=Nostoc punctiforme (strain ATCC 29133 / PCC 73102) GN=Npun_R2080 PE=4 SV=1
-----------------------------------------------------------------------EDFQQLLEDS-LSQPPLRGVVYL--EASA
IPEDVLNALREAQTVSYASALHLVQAVVQ-TPGLEAPRFWIVTRAVSKNPL-QVSQAALWGLGRVINHEHPELSCTCVDLAANAEADME-IL-L-----S
SPDSENQISYHQGVRHVARLERYRGRS------FKVAKDGSYLITGGLGALGLESAEWLVEQGAQHLILVGRNQPSAT---AQDTITQL----ENAGAQV
LVVTADISDAAAATGVFEFIR-SSLPPLRGVIHSAGVVDDGAR-QLSWERFNRVLEPKVAGAWNLHCLTQDLTLDFFVCYSSIASLIGTPGQGSYAVANA
FMDALVCDRQ-AHGLPGLSINWGPWAEVGMAARLRSQSKIVAQGISGITSEKGFQVLGELLGQAAYQGVLPINWNQFFE------------------QS-
---SFGIDEKFFEAFTPKLEQ---------------------PEAEEFDVLQQLK---A-----APINEQRALLTTVCNQVAKVSQINPQQGFFDLGMDS
LTSVELKQRLQKSLGCQIPDTFVFNYPTIEAAVNYIAEK-----------
>tr|M5TNB2|M5TNB2_9PLAN Polyketide synthase type I OS=Rhodopirellula sp. SWK7 GN=RRSWK_00722 PE=4 SV=1
-----------------------------------------------------------------------DNYEKLLGSLSGE-DRPTSIIDLWAIGNE
SENG-NNPAELA-HRECSHALLLLSTLAK-NSSLPIAHTTFVTRAIT-DDV-SPSQAALWGLGRTAMVEMPHLSMTFLDLDSSQSIESCDEV-QTRLVGE
DASSEDHVAFRAGERYVARLEKA-ADLLRVAYPTLSFGNGTVLITGGLGAIGRQVAQYAVTQGATHLAILTRRSSDD----VKDELASM----QECGASV
AVLQGDVSDRESLVAAVRELP-SSYPAIRGVFHAAGVLRDGLQ-TMELDQLDQAMSPKTHGAWNLHDVFD-DQLDFFVMFSSVAGTIGSPGQANYAAGNA
FLDALANYRR-GLGLPATSIAWGPWDAEGMAATPRR--QLAERGMSPLQPSTAMHLLDLAIQNRVTPAVMDVNWNVMLG------------------KM-
---VGGGSS-LMSEFRSATASTE---------------KSNSGGARDEKLVARLM---A-----ASAEERLQQLQSVASELADVDAIEADQPLASLGLDS
LMGMELRSKLESRLGIELPMSALFDDPSVVSLARVAGEA-----------
>tr|Q7UJD0|Q7UJD0_RHOBA Polyketide synthase OS=Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1) GN=RB11975 PE=4 SV=1
-----------------------------------------------------------------------------LAEKSES-LPLAALITLWDPSGK
S----SNPADDA-VAVCQSALKQIRSAIT-HVPVSKRGWWHVTTPVSESSI-DLVHAPLWGMIRVAMMELADLKPSLLETDPSASDQSNLVI-A-----I
AADDEDHVAYRDGTRHLGRLVKR-RAPAETRMS-EEASESTVLITGGTGAIGLKLAKHLIKDGATSIALLSRRQPVGD---VAAKIDALK--QDADSVQV
TVLQGDVGELDSLRSALKQLP-GSLPPIRHVYHAAGVLQDGLM-DMTEEQLRVPMGSKIQGGWNLHVATKDLPIETFVLFSSIAACLGSPGQANYAAANG
FLDALSEYRR-EKGLPATSIAWGPWAESGMAATESS--QLESRGMRLLPAIACLQTMQQLIDAGDQYAVMDVDWPAMTK------------------SM-
---RRSR-P-FFAEFADRSQVDG---------------K-ASVDQVDHEFRAQLS---E-----VPESERTERLRRFASELARLEQIDVKQKLSELGMDS
LIAMELKNNLEQRLAITIPMSALVESPSINSLVGHVVSQ-----------
>tr|A0A0J1BJ36|A0A0J1BJ36_9PLAN Malonyl CoA-acyl carrier protein transacylase OS=Rhodopirellula sp. K833 GN=RISK_001326 PE=4 SV=1
-----------------------------------------------------------------------------LAAREES-KPLAAIITLWDSSEA
S----SDPAGDA-EVACQEALTQVRSAIE-HVTPGKRGWWHVTKTVSASNI-DLAHAPVWGMIRVAMMELADLKPRLLDLDPSATDQSNSAV-M-----V
AENEEDHVAYRGGKRYLARLVKR-HAQDGTRMSKDESAASTVLITGGTGAIGLKLAKRLIDEGATSIALLSRRQPTGE---VAAKIDALT--EESDDANV
IVLQGDVGDLESLRSALKQLP-DGMPPIAHVYHAAGVLQDGLM-DMTAEQLLVPMGPKVQGGWNLHLATKDFPIESFVLFSSIAACLGSPGQANYAAANS
FLDALAEYRR-GKGLPATSIAWGPWAESGMAATESS--QLESRGMHLLPAEACLQTMQELIEAGDHYAVMDVDWPAMTN------------------SM-
---RRTR-P-FFTEFADSSLADS---------------N-SKVDQVDHEFRARLA---G-----IPEDERTDQLRHFASELARLEQIDVTQKLSELGMDS
LIAMELKNNLEQRLAITIPMSALVESPSINSLVGHVVSQ-----------
>tr|Q93H85|Q93H85_STRAX Modular polyketide synthase OS=Streptomyces avermitilis GN=pteA3 PE=4 SV=1
-----------------------------------------------------------------------GVHSDIDALRKAVGAATPAHVLSEG----
---D-A---AAATRGALAGVLSVVQEWVA-DERFSDARLVVMTREL--DTALDLAHVAVSGLVKSAQTEHPDRLL-LVDADDSVTNGGTGGVDPALAAAL
AALDEPQAAVRDGKLYVPRLARITPPEEP---GHAWDPEGTVLLTGATGGLGRSLARHLVAEGARRLLLASRRGPAAEG--VGELVAAL----SELGAHV
DVAACDIADRDALAELLASV--PAEHPLVAVVHAAAALDDGVITALTPGRLDTVLRPKADGALHLHELTRDLNLSAFVLFSSLAGVLGSAGAAGYAAANA
FLDGLARQRR-AAGLPGTSLAWGLWTDNGMGDRIADRNRMGRAGVVPFSPAEGLALFDAALTVDRPVVPVRLDVPGLR-------------------AMA
---RAGMLPAVLRGLVGDTGA-A---------------AGEAAAAGTTALARRLA---G-----IPEADQEKVMLDVRHQAAAAARIEPTTAFRDIGFDS
LTAVELRNRLKAATGLRLKPTLVFDHPNPVAIARLLHKD-----------
>tr|A0A0A7AD06|A0A0A7AD06_9CYAN HapB OS=Hapalosiphon welwitschii UTEX B 1830 PE=4 SV=1
-----------------------------------------------------------------------KDFQQLLLEQVACKTSWRGVVYLWSIDTV
SADALVADLEVVSQTGCGGVLSLFQSLIS-KEFSPPPTLWLVTKRVSIETLVGVAQSPVWGLGKVIKDEHPEFNCTLVDLDPQGNNNAQLFA-E-----P
KPTSGDHIAFRNGQRYVNRLVRSDKIV------LQLKADATYLITGGLRGIGLLVAQWMVDHGAKHLVLVGRSRPDSA---ATEILRRL----EEVGTQV
VVIQTDVSQEQEVTSLLNQIK-TSMPQLRGIIHSAGVFEDRRV-DHQWQLFAKVFAPKVSGAWNLHTQTQDLPLDFFVLFSSAASILGPAGLANYAAANA
FLDTLADYRR-SLSLPGLSINWGPWSMVGMANAVRGEVQWATKGIKPIESQQALSILENLLPQDAAQGVMQVNWSKFLQ------------------QF-
---SRSSYPNFVSEIAQQAEKSI---------------PQKQQKVNSPQLLDQIK---A-----NSKDQSQSLLITLGEQIAKAGLN-IDEPLNQMGLDS
LMVIELRNRLRAELGVDIPITKFLDGLSVVGLTKLASEQ-----------
>tr|D7BSN9|D7BSN9_STRBB Putative type I polyketide synthase OS=Streptomyces bingchenggensis (strain BCW-1) GN=nanA2 PE=4 SV=1
-----------------------------------------------------------------------DRYPDLDALFRAVGAPAPDVVIGNDP---
------AG-ADTGLATARRMLTLAQEWLA-GSGADGARLALVTRRTGDDERVDPSAAAVWGLMRSAQTEHPGRFL-LIDTDTDADTD----Q--DALREA
VRTDEPQLALRGGRALVPRMARVDAEPE-LDIDPAPDPDGTVLITGGTGTLGGLIAEHLVRSGVRHLLLLSRRGPDAPG--AEELMARL----TELGARV
RVAAVDVGDATALGEAVAGV--DPAHPLTGVVHAAGVVADAMLPSQDDERLVAAWSAKAAAAARLHDATAGLPLGMFVLFSSFASTLGTAGQANYAAANA
YCDALVERRH-AEGLPGVSVSWGLWSAASLTGGLADVARIARQGIVPNSTEQGHDLFDAALGHGRPALALNLDTRALA-------------------AQ-
---PVAALPAPLRALAADAQARP---------------TA-AAAEEPGDWAARLG---A-----LAPAEQRRLLTDVRRHAATVEAVPADAAFKELGFDS
LTAVELRNRVTAATGLRLPATVIFDYPEPVALAERLRTE-----------
>tr|Q846X5|Q846X5_STRCM Monensin polyketide synthase module 2 OS=Streptomyces cinnamonensis GN=monAII PE=4 SV=1
-----------------------------------------------------------------------PCYPGVGAL----NASPPSMILDTT----
---------GGDGLALTERVLRVIQDFLA-APSLEQTRLAFVTRDTGSTEAVDPAVAAVWGLVRSAQSENPGRFV-LLDTDAPLDQASVAPL--DAVRSA
VEADEPQVALRGGRLLVPRWARAGEPVE-LDVPAPLDPDGTVLVTGGTGTIGAAVAEHLARTESKHLLIVSRSGPAAHG--AEELVSRI----AEFGAEA
TFVAADVSEPDAVAALIEGI--DPAHPLTGVVHAAGVLDNALIGSQTTESLTRVWAAKAAAAQQLHEATRESRLGLFVMFSSFASTMGTPGQANYSAANA
YCDALAALRR-AEGLAGLSVAWGLWEATSLTGTLADRARIDRYGIRPTSAARGCALLAAARAHGRPDLAMDLDARVPA-------------------AS-
----DAPVPAVLRTLAAAGAPRP---------------TAAAAADGATDWSGRLA---G-----LTEEARLELLTEVCTHAAGVGAVQVDAPFKELGFDS
LTAVELRNRIAAATGLKLPAALVFDYPQARVLAAHLAER-----------
>tr|I3WY26|I3WY26_9ACTN Laidlomycin polyketide synthase (Module 2) OS=Streptomyces sp. CS684 GN=ladSII PE=4 SV=1
-----------------------------------------------------------------------DRYPDLAALVGATGAAVPDLVFDTL----
---------AGDELHVTEQVLALVQDFLS-APRLDRARLVLVTRDADDPEGPDLAGAAVWGLVRSAQSENPGRLV-LLDADGPLDRDA--VA--DAVRGA
GGVDEPQLASRGGRVLVPRWERAARTGE-LDVPAPLDPDGTVLITGGTGTIGAAVAEHLARTESGHLLLVSRSGPAAEG--APELAARL----GELGAEA
TFVAADLSEPGAVAELIAGI--DPAHPLTGVVHAAGVLDNALIDSQNPERLARVWQAKAATARRLHEATEEARLGMFVMFSSFASTLGTPGQANYAAANA
YCDALARHRR-ARGLPGLSVAWGLWEAVSLTGTLADRARIDRYGIRPTSAAKGCALLSAARAHGRPDLAMDLDARVPA-------------------AS-
----QETVPVVLRSLAAAGAPRP---------------TAAVGA-DAADWPGRLA---A-----LTGEERLELMTDVRTHAAGVGAVQVDTRFKELGFDS
LTAVELRNRLAAATGLKLPAALVFDYPQARVLAAHLVER-----------
>tr|A0A014L9G0|A0A014L9G0_9ACTN Beta-ketoacyl synthase (Fragment) OS=Streptomyces sp. PRh5 GN=Z951_43560 PE=4 SV=1
-----------------------------------------------------------------------GGHPDPAALVAALDEPVPPVVLLTKPTRE
GAE---EV-SAEALSTTERALELVRGWLA-EPRLADARLVVVTRAVDGPARVDLAAAAVWGLVRSAQSEHPGRFV-LLDRDDEPDSGVDGPHTDVAVARA
VQMDEPQLALRAGRALVPRLVQAGTGGAGLDVPAPVDPDGTVLITGGTGTLGALVAEHLVRTNIRHLLLVSRGGPDAPG--AKELVARL----ADLGAEA
RIEAVDVTDGAAVHDLVADV--DPAHPLTGVVHAAGVLDDAVVTAQTPERLARVWGPKATAAAHLHAATARLRLGMFVMFSSAAGVLGSPGQANYAAANA
YCDALAVHRQ-AMGLPAVSVAWGLWADASMTGHLADLARMSRSGIAAMSGARALGLMDAACWHGAPHAAVQLDLRTLA-------------------AR-
---PADTLPALLRTLLDSGTTRR---------------TAATG-APAAGLVTRLR---A-----VPIEEQHRILLTVRTQAAAVGAVSGDTPFKDLGFDS
LTGVELRNRLAAATGLRLPATVVFRHPTPSAIAAELREQ-----------
>tr|A0A0Q4PEP2|A0A0Q4PEP2_9BURK Uncharacterized protein (Fragment) OS=Duganella sp. Leaf61 GN=ASF04_26185 PE=4 SV=1
---------------------------------------LESAQQTVVRVAFGASFVVAGS-SCTIRSHCEEDYQALFAVLGQLPDRVVHLGSL-ALPAA
SASYQD-FVL-AQQTGMLSLIYLVRNWARAMPDTQLHVVTNDLFDVLGSEVLLPARSTVAAICNSIPQEYPQVACSHLDLALTPHCAT---DLGQRAALS
LRRPERLVALRGAARWQRGFEP-QVAG--AVAAHSFVQGGVYFITGGLGKIGLALARQLCERFHADVVLTTRSAPSAEDADRLLQVDRCT----LDGGRL
RVLQADAADREAMAAALAAAEQEFG-RIDGVIHCAGDVADAIRPTVGEADCLRQFLPKVQGLLFLDELLRDRDVGFCMAMSSLSAVLGGIGFGVYAASNT
YMDTFCHQKH-QQGDPWISVNWDGWNFAQNAED-KFFDMLHENHIPGSEGLAALAQAL--HLGHA------------------------PQLVCSTTDLA
TRHRRWI------------------ERAVPA--------T-APAPDADAAGE----TPAVMVLDGGRNATDASLLQIWRDLFGMAEVGIRDNFFDLGGDS
LLLARLLARIRAEFGDAITLAGMFNSPSIEGISDLIGVA-----------
>tr|A0A061MTC3|A0A061MTC3_AGRRH Uncharacterized protein OS=Rhizobium rhizogenes NBRC 13257 GN=RRH01S_06_02120 PE=4 SV=1
---------------------------------------LDDSSVQIVRVTFRSEFVLASALLFGPRWHCFRSLAHLSLASADIGAFPLHPALLDARRVR
ENVYDV-TLFADDAGEVPTPTHIVYIVGDSVPHGA-GHPANALFGDLADEQPRAAQAVLLGAVRAAMWEFPNLRCRHIDLPVGAGSAD---QAALRNALN
HSPLAPTVAVRDGAFYEPYFRSLPA----FATAPRFVDGGAYVITGGLGGIGLALATHVAISATAPCFLVSRSGASHP---AEASIAALS----ALGAVV
TVVQADCGDRDAFAAALADIKSHCG-RIDGAIHAAGVEASGLIQLAESDAWTRVLAPKTIGTDVLIDALRDEQPDFILLCSSLAAVLGGLGQADYAAANA
YVDASAQAAR-REGLPVVAVNWDAWAEVGMRVA-YDRAHPNQAPIDATEGCRLFDIAL--AHADA------------------------QIVVHKAQDIE
TLIRSLA------------------NEPDRA--------------GPRGVAS----SATTAEHVAPRNALERQLAELWRELLGGELPGVQDDFFDLGGHS
LLGAQLISRVRERFPECLTLAEFLDEPTIERMAASLGTV-----------
>tr|A0A0A3JL96|A0A0A3JL96_BURPE Amino acid adenylation domain protein OS=Burkholderia pseudomallei ABCPW 111 GN=X946_4838 PE=4 SV=1
---------------------------------------FAGVQRS-LRAVFKQDFVLESRPEYGPRWHCIDAVARLRLPHRDLPAFALHPALLDAIERA
PRTFDV-TLFSNAQARRPAPSQIVYAWRADESRPA-LDATLDGFTHLADAPAACATAATAASLKAVQWEFPDIVCRHLDVDDDEPSTQ---QALHT-ELG
YFDKAATVCLAAGSRETLRFVDAPAPD--TAQGAPLRDGGVYLITGGLGGIGGELARHIAETAPGAKALIGRQRE------QAARLRALE----AAGADV
LVLRADVADARQMRTAIAELHARFG-QVNGIVHSAGVEASGLIETGAPDAWRRVLAAKVAGTHNLIDLVAADRLDFVVLCSSLASLVGGLGQADYAAANG
YLDAIARHWS-RARIPVVSLNWDAWTETGMAVD-YTERTAHR-GADSVEGRAIFDLAI--RMPGS------------------------GIAQLAVSKFG
FDR-----------------------QPS----------------------N----AQRKTAAAPPSSDVERTLVGLWRDLLGVDDVGIDDDFFDLGGHS
LLATQLISQVRDLYGRCLTLGEFLDAPTISRILRSIDAT-----------
>tr|A8KCI9|A8KCI9_9BURK Peptide synthase OS=[Polyangium] brachysporum GN=glbC PE=4 SV=1
---------------------------------------FPGARRR-VRVVFTQEFALESATDYGPRWRSVSALAQLALPTDDLPDFVLHPALLDAIETA
PRVYDV-TVFADEQTQRVAPQHVVYTWAGAAAE-----GGGEVFETLARTLAACHAATAVGLLKAVQWEFPDIACRHIDLEDTEAATQ---ALLHA-ELG
SVDPVSSVTLGQGKRETPQYVALPQPV----ESDRLVDGGVYLITGGLGGIGFELARHIATRRRGVKALMSRTGLDGASPGRDACVRLLE----EAGAEV
LVLQADVADAAQVADAVDRLRQRYG-RVHGVVHAAGVEASGLIETGSPAAWRRVLGAKVDGIDHLRDLIEHDRPDFVVLCSSLASVVGGLGQADYAAANA
YLDAVARHWR-GQGLAAVSVNWDAWSETGMAVA-YAARTAKQ-GATAVQGRLVFDLAL--GLTHP------------------------QLVVNAA-DFG
GAAPRTP------------------ARQA----------------------K----AARVPSSPPTGTDAEQVLTALWQELLGVEQIGLEDDFFELGGHS
LLATQLISRVRDLYDRCLTLGEFLDQPTLARILRSLEAD-----------
>tr|A0A088X784|A0A088X784_9BURK Amino acid adenylation domain protein OS=Burkholderia oklahomensis GN=DM82_4026 PE=4 SV=1
---------------------------------------FAGARRS-MRVVFTQDFVLESRGEYGPRWRCIDAVARLRLPSRDLPAFALHPALLDAIERA
PRTFDV-TLFSDAQARRPAPSQIVYAWGAGEARPA-HDAAHDGFAHLADTPAACAAAAMAGSLKAVQWEFPDIVCRHVDVDDDEPSTQ---QALLA-ELG
HVDKAPTVCLAAGRRETLRFVDPPVPA----SNGPLRDGGVYLITGGLGGIGGELARHIAETTAGAKGLIGRQRD------QAARLRELE----AAGADV
AVLRADVADARQMQAAIAELHTRFG-PVNGVIHSAGVEASGLIETGTPDAWRRVLAAKVAGTHNLHDVIATDRPDFVVLCSSLASLVGGLGQADYAAANG
YLDAIARHWR-RARILVVSLNWDAWAETGMAVD-YTERMMHR-GADAVEGRAIFDLAI--GMPAA------------------------GVAQLAVSKFG
FDH-----------------------RPA----------------------D----AKRKTAAAPPSNDVERTLVGLWRDLLGVDDVGIDDDFFDLGGHS
LLATQLISQVRDLYGRCLTLGEFLDAPTISRILRSIDAT-----------
>tr|B1GYG1|B1GYG1_CHOCO Polyketide synthase OS=Chondromyces crocatus GN=ajuG PE=4 SV=1
TWSYEIRWEAMARTPPRRPEKGAWLVLADRGGAADQLTR---RGHVALLATSGPREA-LGGGRFHIDPASRADLAWLLDHARGAGPAVRGVVHLLSLDAP
PTEALTETLVAAQQLGCATVQALLDAALP--ISWLITRGAQPAGG--APEPLAVAQAPLWGIGRIAALEHPELWGGLLDLDPHAPSAIQAEAARVVDELL
GPDGEDLLALRGAERRVARLIRSPALPLPAERPG-LRPDATYLITGGLHGLGLEVARWMVEAGARHLVLTGRRGLPDPTADGAAEIANLER----AGASI
RIVAADASNLGQMEALFADIA-RHGPPLAGIVHAAGTSRPALLAQTDQAAVEFLLAPKVQGAWILDHLTRELDLDFLVLFSSAAAVWGGGLLGPYAAANH
FLDAIAHHRR-ALGRTALSINWGSWQAGSMLTHMPEDRYLEGIGFGTMPLDEALEVLGWLLGTPLAQRAIAIDWG----------------------RFK
PIFEAR-----------------RRR------PLLDLIEAPAANASPAADELLLRRLEADGP-EARMTRLIEHTRRLVTETLQLAAFDLDQGFFQLGMDS
IMSVQIRKRLEADLGRRLPPTLAFDHPSVRRLATYLATE-----------
>tr|D0LQX8|D0LQX8_HALO1 6-deoxyerythronolide-B synthase., (Acyl-carrier-protein) S-malonyltransferase OS=Haliangium ochraceum (strain DSM 14365 / JCM 1
APLLRREWRPAERPAASAAAPGPWLLVGGGA-ARARLEA---GGHEVVALDPGELA---------------GDPAAVERDSAGGAGAVAGVVHLASLTAE
APAGASSEPVWASALHLVHQGW------R--DAWLVTAGAQRAA---PGGVAALLGAPLLGMARTLAYEHPELRCTRLDLAADPADGADALAEALVAELL
ADGGDDEIALRGRRRFVARLGVGAMPAAQLELAGAIRGDASYLLTGGRGGLGLSLARWLFEQGARRLLLAGRSAPSAA----AEQLAELSR----AGAEV
VLATVDVADPAAVAQLLADCE-RPEAPLRGVFHLAGILDDGLIAQQDRARYRRVLAPKIDGAWHLHRLTRERPLDLFVLYSSVAALLGSPGQTGYAAGNS
FMDALSEIRQ-DAGLPALSVAWGPFAEVGLAAAREERERLHDRGMSSMSTQDSEDALGALLARDEPWVGVVLDVG----------------------RWL
DFYPTL-----------------G-AS----AYFGQLVGD----APGDAQQALRARLEAT-P-APLRAQMQRLVREQLARVLQCEAIAAETAFTALGLES
LTGLELRNRLEAEVGLRLPATLIWTHGNLASLAGELLAR-----------
>tr|A8YP97|A8YP97_STIAU Polyketide synthase AufI OS=Stigmatella aurantiaca GN=aufI PE=4 SV=1
EQVLRLEWREAERTAGAGAAAGHWILVGQGG-VRERLEA---QGHTVAVIDTHELA---------------SDAVAHTRESLSRQGSCTAVVHLASLSMA
VSSGESSEPVWASALHLTQQGW------R--DAWFVTQGVQSAS---NAGATALAGAPLLGLSRTLSYEQPELRCTRLDLPAGPSAGVDGLADELTAELL
ASGADDEIALRGGQRFVARLAFGPLTEVTIEGQGAFRADASYVITGGLGGLGLSLARWMVEQGARRLVLAGRSAPSEA----ARKLGDLEQ----SGATV
VLTAADVAQPAEAERLLREAE-TPNAPLRGVFHLAGILDDGLVTQQDTARFRRVMAPKIDGAWHLHRLTRERPLDFFVLYSSIASLLGSPGQTSYAAANS
FLDALAAHRR-ATGLPGLSLSWGPFSEVGLAAAREVRERLQDRGMASMSTQEGETSLAAILGRDETWVGIVLNVA----------------------RWL
DFYPTL-----------------S-AS----TFFSGLIGA-SAASVGHTHQALVAKLRAT-P-AQLRIQLEGVVRHQLAKVLQCEAIAPQIAFTSLGLES
LTGLELRNRLEAETGLRLPATIIWTRGNLSSLARELLDR-----------
>tr|G8M270|G8M270_CLOCD Beta-ketoacyl synthase family protein,phosphopantetheine-containing protein OS=Clostridium clariflavum (strain DSM 19732 / NBRC
NCFYKYEWVPQRVKYDEHKIEGSVLIFKDELGLAYKLRE---QGMDVIEVNYGNCFQKINDNSYTVDNSYE----SYQ----VSEISCRKLVKILHMFTV
NNGEYD-------EFSSS-----DRAIEK--GIFYMIKGFVNITG--EEKVIIPHNAALLGLSNAIKNEYFKLNCKRIDVDNE-----------------
----------------------------EIGENKVFKQQGVYLVTGGTGGIGLEVCKYLSTSKV-NLALINRSNFPDRKETKQINIMDIEA----QGSKV
MIFAVDVSDYNAMKELTDDLR-QRYGRINGVIHGAGVAGEGFLYNKDVKKFSEVILPKIHGTRVLFDLTKEDNLDFFIMFSSVASLFDLPGQGDYIAANS
FLDSFCSYGK-RKGIKTLTINWPAWKETGMAFNTNTN----DTVFKAIHTNHAIDAFEYSLNKDIDRVIIGLDFN----------------------FIG
LLKEKP--------------------I-----RFSEAIENRSD--DTKAYKSVEINLKGK-G-EESYSIEVN-LSKIWAEVLGLDEINIYDSFYELGGDS
ILATRLLQEVEKEYPGILDITDIFSYSSISKMAEYIESK-----------
>tr|Q0B307|Q0B307_BURCM Beta-ketoacyl synthase OS=Burkholderia ambifaria (strain ATCC BAA-244 / AMMD) GN=Bamb_5921 PE=4 SV=1
--QLVEHWVERRVEHETAPSIAPRLVLLDEAA-----TA---RSWLAASGE-V------------IDASGLDDAA---VLAALGS---EPAVLLAGLPAA
PAADQDESWR-MPLLGLVGADRLGDALEA--AGATVRFGLLSADL--DGQGGSPLHGFALGLAKSLSLEWPGRAVTLLDVDGEGSPDA------------
-------------------------LAAPP-LASWPRADGPYLLTGGLGDLAAETCHWLADEGVRHVWLTGRREADA---AIERQLALREA----TGLRV
DYRACDIADRDALAALFADAA-RDG-PLRGIFHCAGVLADGAFATLDDGAFERVARAKVLGSWNLHQLSRGLDLDAFVLYSSLASLLGSAGQANYAAANG
FMDQLARSRR-ALGLPALSLNWPGWGGVGMAARNARG-PG--SGLRRLAPERALGELGRALAGGQAQVGIAVDWS----------------------VFG
RDWRAS-----------------AAAVP---ALVEDWFAAAAGAVPAEAARELAAAVDVDAR-LEIARHLVGIVR----RIMALRPLAQNKSFHELGLDS
LMAIELKRALQEGFAARVPATVMFDYPDIDSLAHWLAGP-----------
>tr|A0A0D5EGX0|A0A0D5EGX0_9BURK Short chain dehydrogenase family protein OS=Burkholderia ubonensis MSMB22 GN=BW23_5790 PE=4 SV=1
--TLVERWVERAP-AEAAPSAAPCLVLLDDAA-----A-------LAASAD-A------------LDASALDDAA---VLDALAG---RPVVLLAGLPAA
PADD--EAWR-APLLRFVAASRLGDALEA--AGGTVRFGVLSADL--DG-GGAPLYGYALGLCKTLSLEWPGRAVTLLDVDAPSSRHA------------
-------------------------LAAQPAALPWPRADGPCLLTGGLGDLAAETCRWLAAQGVRHVWLTGRREPDA---ALARRLALRDA----TGLRV
DYRACDVADRDALAAVFAQAA-QHG-PLRGIFHCAGVLADGAFATLDDAAFERVARAKVLGGWNLHQLSRGLDLDAFVLYSSLASLLGSAGQGNYAAANG
FMDQLAHARH-ALGLPALSVNWPGWDGVGMAARSGRR-PGEGSGLRRLAPAQALGELGQALASGRAQVGIAVDWP----------------------AFG
RDWRAP-----------------A-AAP---ALVEDWLAAPAAARAGEAARELDAA-AGGER-LDVARHLVRIVR----RIMALRPLAHDKSFHELGFDS
LMAIELKRALQEDF-TRVPSTVMFDYPDIDGLAHWLAGP-----------
>tr|A0A0L0L431|A0A0L0L431_9ACTN Polyketide synthase (Fragment) OS=Streptomyces stelliscabiei GN=IQ64_12020 PE=4 SV=1
EDLYRLEWPTLPQPAATAD-TDVWAVIGAEAP-----------DWA----AHG------------ITRS-ATDLKALSEITEGAA---RPTAVLAHVPAA
PEGQDRVRHVTGRTLTLV-QDWLADST-F--ADVLVTRGGVPTSA--DGDAPDLTHAAAWGLARSAQTENPGRFVL-ADLDGTGA--SRDA----L-AAA
VASGEPQLALREGRAHIARLARVPA---QAETLDW--RPGTVLITGGTGAIGSVLAHHLVAHGVKRLLLTSRRGPAA---EGAADLVGLAA----LGAHA
EVVACDVADRDALARLLGSLP-EAH-PLTAVVHAAGTIADGVVDAMTPARLDTALRPKVDAAWNLHELTEGMDLSAFVVFSSIAGIFGGMGQGNYAAANA
FLDALAHHRR-ANGLPAASLAWGLWANKGGMSGGLDERI-ARGGIVAFSPAEGAALFDSANATGEPVVLPLLDTG----------------------ALA
A-QTGT-----------------GGVP----ALLRGLVRP-VGEVAPDAADTLRRTLAGQ-P-EQRRETLLDLVRGHAATVLGFASVDAERGLLELGFDS
LTAVELRNRLGAATGLRLPATLLFDHPTSAAIARQLSVE-----------
>tr|V9XQV9|V9XQV9_STRAO Polyketide synthase OS=Streptomyces albogriseolus GN=shaB PE=4 SV=1
NSLFLLDWTEVSSVQEAVP-VPVWVPVVSA-----------------------------------------GDVVELA----GAG---AGVPAVAVLEAV
AAGDGAALGLTSRVLGVV-QAWLGAAG-L--ENVVVTRGAVPAG---DGVVSDPAGSAVWGLVRAAQAENPDRIVL-VDADPAAAADGRDA----VLAAV
TAGDEPQLAVRGAAHFVPRLARATD-RVPDGTPVF--AEGTVLITGGTGSLGALAARHLVSYGVRHLVLAGRRGPDA---EGAQELAELTE----LGAAV
EVVACDVSDRAQVEALLATVP-DAH-PLRGVIHTAGVLDAGVIGTLTPERLARVFAPKVDAVRHLDELTRGLDLDAFVVYSSVSSVFMGAGSGSYAAANA
YLDGLMAARR-AEGLPGLSLAWGLWEQTSGMAANTDDRMSRRGGLQMMTLTEGMDLFHAALGSPRSLLVPALDLR----------------------GVR
ADAAAG-----------------GGVP----HMLRGLVRT-TG---TAQDGELLRRLAGL-P-TADQETLVDLVRGQAASVLGHDGVRADTAFKDTGFDS
LTSVELRNRLRAATGLKLPATLVFDYPNPQALARHLHTE-----------
>tr|Q83WE8|Q83WE8_MICGR Protomycinolide IV synthase 3 OS=Micromonospora griseorubida GN=mycAIII PE=4 SV=1
ELLYRVDWPLLTVGPAQPP-KH-CAVVGDDPY-----------GLAAVLGDQG------------VTCDVHPDVAAFT--IRSVT---MPDVVVATLPA-
-STDPDVRDVANRALDLA-QWWLSVATDA--EAVVVTSGAVATQR--GEPLRDPAAAAAWGLLRSAQAEDPGRLVLLDVAGQRPD--G--A----ALLAA
LASGKPQLALRDGNLRVPRLTRTETKLVLTMPATI--PGGTVMITGGTGNVGGVLARHLVEVRRGTCRSSSRQGPAA---PGVDDLAELAD----LGATV
TVHAGDVADRAEVERLVAAVP-AEH-PLTAVVHAAGTLDDGMIPSLDQEQVGRVLRPKADGALYLHELTRGSALSAFVLFSSVAAVLGGPGQGSYAAANG
FLDAFAQNRS-AAGLPTVSLSWGLLAGAARMTAHVDQRRMSRGGILPLSGRDLTALFDAALAGTEAHQVPVIDPS----------------------AIP
DD---------------------AGVS----PLLRGLAAG-AVASEPVDVRSLVERLTGM-P-EEAQQLLENLVRTHAAAVLGYDAIQGDTAFMEIGVDS
LAAVDVRNRLAAATGLRLAASTDFDHPTPVVLAGHLRAQ-----------
>tr|U5QGQ1|U5QGQ1_9CYAN Beta-ketoacyl synthase OS=Gloeobacter kilaueensis JS1 GN=GKIL_1822 PE=4 SV=1
DSLYGVQWQKVSRAATPS-PTGRWLIAADRTGLACQLRA---AGAECELIFAGDA---SAG--PTIDPA---DPGAFR--VLSTHPPVDGVIHLWGLEAE
AT-------STGQLFGCG-LHWLQALAAS--GTWLVSRGAQS------TETLAVAQTPLWGLGRAMSQEQPEHWGGLIDLDPAFDPAAA---TALVQELL
IPDTERQLVLRGGERYAPRLVRTAL---PATVQPLLPGDATYLIVGGLGGLGIEVAQRLVQRGARYLVLLGRRAPTSA-------IQELEA----MGAQL
LVVQADIADQEQLQELLEKID-LHLPPLRGIVHAAGIVDDGVIEKLDWSRFERVLAAKVSGAWHLHHLTRSYPLDFFVCFSSMAALLGPRAQASYAAANA
FLDGLAQLRH-AEGLPALTINWGPWGEVGMASALPERQRLAEQGLEPIAPAAGLAILEAALTAPGFQLGVLADWQ----------------------RFA
HQFHDR-----------------AL-W----NFVAGLVPAPD----------------SGTP-AESLERLIALVA----RVLKLQRIDQRRPLVDLGLDS
LMALELSDQIQAACGVNVPVARFFGRTDIAQLAEQVREE-----------
>tr|K9M8B5|K9M8B5_9ACTN SiaE OS=Streptomyces sp. A7248 PE=4 SV=1
--VFTQAWEAAEPASVDVLLGRVLVLLPEDGAQEEVRSRLAGHPGDVVFAAPGAAFQRTGGGGFTVGGDLEAGYRELLRTVAADHGPIDAVAHLWATERT
AEGSHLRAFLRALA-------------QEVQQG-ALTVPGRVLIGGDDGQRCEVESW--LGFERSIPLVVPGTSVTILAMD---GEAAGRLPGILADELG
AE--PVSTLHRNGRRWAQQVRPAELRPVD-AAGDRLRDGGTYLITGGAGGLGAIFGTWLAREYRARLVIVGRRPAEDE--DVRARLAEL----DRAGAAV
LYRQADVCDPVALTEAVRTA-VEHFGRIDGVLHAAGVEEHGSIAERDAATFARVRAPKVAGTLALAHADQGGGPDFVCYFSSSAAVLGDFGSGDYATANR
FQVAYAEMLARSEGAGRLAISWPLWRSDGMNFSDAGDFYLKSSGQRYLEPSEGTGLFRLLLAQPGA-AYLALAGERDRIRGMLRVPPAAPAPASG-----
---------------------------AVPAPAVDPVVESGHGHPSRAAAGSAGQSA-DEIAADHVADGLRRELNDVVSQVVPADKLAADENLREFGFDS
ITLVEFAGMLTESLGVDVTPHVFFSYPTLRTLHEYLLTG-----------
>tr|I2HQK3|I2HQK3_9BACI MlnG OS=Bacillus sp. 5B6 GN=MY7_1336 PE=4 SV=1
--YYKPEWTESFIPNKSVPLTGLLLIFAENERQIQELSGL---KDTLLFVIRGKEFAVLHDDTICMNHVKKDDYLKLFRYIHDHYQLPEKILHLWSDSQA
D----MSKGIQKQL-------------ENG-----------------------------------LFLIEKIIKLTHIFENKEQSEGTGAALPAIADI--
--YECDRDTHFYEKSYNKAGSF--------DLTQPLKHHGNYLITGGLGGLGYILAKHLSEKWKANLILTGRSDLTEE---QEKKIEYL----RSSGSTV
EYIRSDVSKQSDAERMFAFA-KEQFGTLHGVFHSAGVLRDSFILRKTKEEIDQVTGSKVYGTLWLAEEIKKMKVELLVLFSSTSAVFGSAGQCDYAFANA
CLDQYAAVMTAKE-GRVVSVNWPLWTSGGMNIDDGISYMKQELGLDPLDDGDGIQALENSLCQSSE-QLIALKGRKEDVLK---RAGTS-----------
-----------------------------------------------LH--SDQQED-ADLQNDELRQNIISYLKNIMSEELPTSLIDEKQYLEKYGIDS
VMIMRLTKKLEQSIG-RLSKTLFFEYHSISQLAEYFLSH-----------
>tr|A0A0K6L958|A0A0K6L958_BACIU Polyketide synthase PksN OS=Bacillus subtilis GN=pksN_1 PE=4 SV=1
--IYEKEWVKYIFQRTPRQMTEPILFLASDESLYSVMKRQEG-AAPFIYVSPGDRFEAGRNGCFKMNFTQKEDYEALCRALVSQNIKPRHIVHFLSVGAF
R----DTDKMREQL-------------DKS-----------------------------------LYIMEPKAEVLYLYVQGESMSNEPFTKELIADVIF
CEWQCVSFTCYHYKKVNKGGSP--------ENNFNIKENGVYLITGGAGGLGFLFAEYLAKRAKVNLILTGRSPSSME---IEQKINTL----KKLGSEA
VYIPADISKEKETDILIDQI-RRTFGRLNGILHSAGLVDDAFVIKKRRDRIEKVIAPKVFGTVWLDKAAKGESLDFFVMFSSLSSILPNAGQSDYAFANG
CMDSYTDYRIMKN-GKTLSINWPLWSAGNMSVGPELQVL-RETGLDLLSAESGLASFQNCMSSNAS-QLAVINGSEEQLLS---VDNTT-----------
-----------------------------------------------DVTSESDHEL-PQISENQLKKQTVCLLKEIIGAERPTDSILSGDTFDRYGIDS
LTILGLTSRLEKHFG-SVSKTLFFEYSSIDQLAEYFLEH-----------
>tr|S0FP06|S0FP06_9FIRM Polyketide synthase like protein OS=[Clostridium] termitidis CT1112 GN=CTER_0310 PE=4 SV=1
-WFYEPVWSQSELQSASKEVRTCYLVFEDSCGLGKETSEYLEKSGHVVSVEQGEQFCHIDERKFMVNPESYSDFDELLKKGLPADKSKLQVLHFWTVTGA
E-NLSDENLKFHKKIGYDSIISLTQAIGNNGRSADICLVSSNMQCVNGKERIEPGKSTILGPCRVIPKEYGNISCRSIDIPLTDLVNKHNLVETILTEIN
NQSDDNIVAYRDGKRWKPYLQDIALKETGSLD-NKIRKNGVYLITGGLGGIGFVLAEHLAKTARAKLILSGRSELPELSEHDENKIIKLR-QLEEMGSRV
IVISADVTDAEKMRKGISEAESVFG-SVNGIIHAAGIAGGGMIQQKTPQMSEEVFAPKLYGALVLYDIFCRAELDFVIFCSSLQSLMGDLGQADYCAANA
FLDAFAGCWNSKGHNRITSVDWDNWQETGIAADTQVPDNMKRREILSISSREGVEIFERVLIS-------------QPQQVIISAQP-------------
------LQERIE----------LSKA-----FSQDNFPG--NGTFDEADQAGKVQI-----KGSISKNEIQNKVADIWKKVLGVKKLGPNDNFFDLGGNS
LTGLQLVAEIKREFDIQIAPVVIYEAPTISAMARLL--------------
>tr|A0A0K0SI92|A0A0K0SI92_BACT3 Beta-ketoacyl synthase OS=Bacillus thuringiensis subsp. indiana GN=NF53_p6006 PE=4 SV=1
-WFYAPGWMEKEIVDVTKESTKSWLLFLDHIGLALK-EKLERDGHRVITVSVGPSYKKISLNEFTICPTKQEDYYQLFNELQKQECLPEEIVHLWNVDNK
--DLGI----ETLDTGFYSLISLAKTISKFNYPININVMTNNMQKVVGDESIIAEKSTLLAPIKVFPQEYPNIRCRSVDFMLS--DNEEALISNLYSEIQ
TDIIDTVIAIRNNTRYIRIYEPILDEKVSASKIPNIRSEGVYLITGGMGGVGLKLAEYLARTVKAKLILVSRTALPDREEWDQIRINHIQK-LESLGAKV
MTAVADVADEEQMRNVIHQAEANFG-HINGVIHAAGVLRVKPMEKISRIECEEQFLPKVHGVLVLDKLLSNYDDFCYLVS-SLSPILGGLGFVAYSAANL
YLDSFSDKVSNTSNNRWTSINWGDWQYTGAQ---QVNKIFNAQSIEALE------------MT--------------------SE-EGQKTFQCVLGLNG
----------LNQVIIS------SGDLNKRF---DQWINL----NS----RKRISELETQGDKFRNQDEVEQIIIGIWKEFYSVDTVNVNENFFDLGATS
LHIIQIHERLINRLEKQISIGVMFEYPSIRSLAKYLSG------------
>tr|U4R156|U4R156_9FIRM Thioester reductase OS=[Clostridium] papyrosolvens C7 GN=L323_09740 PE=4 SV=1
-----PIWRRGNLSYGSKKTFKNILVFIDQTDFGNNLAGSLESAGKQLTFKSGASFCQDIESGYFINPDISDDYKNLFRELYKSQNIPDTILYLWTLTE-
-DNLHESKVNTAVDMGFYGLIYIAQAIGELNIPISINVVT-NSMHMSGEENINPEKAVIAGPIRTIPKEYTNIKCTGIDIVVP----QEDKAKCLLAEMA
ATDNEPLVAYRGNYRWRQSFDEIQLNEC---KGVPWRENGVYVITGGLGGIGLAISEYLAGAVRARLVLIGRTEIP---PRENDYINSTEKELEELGTEV
LPINADVSDNYRMSKAMSVIHERFG-EVNGVIHSAGLPDGGLIQLRNRETTDSIMSSKIQGTLEINKFIEHNKDFMI-YCSSLSSIIAPFGQIGYCSANN
FQDAFSQHQCNKGHTYTASINWDTWKQTGMAVNLACAHSS-DNLENGMLISEGIEVFKRILN------------SNLPNHLLA--QV-------LISPYP
---LEAYLKRIWD---------MEHEQ---FKIKSE----ESNNPEE----------SLNLQDITSQSDIESKLTDILKEILGYPDIGRDDNFFDLGAYS
LHLIQLRQRLKAVLNVDISIVSLYANTTISSLSRYLFK------------
>tr|D2JNV8|D2JNV8_9NOSO Trans-AT hybrid polyketide synthase-NRPS OS=Nostoc sp. 'Peltigera membranacea cyanobiont' PE=4 SV=1
----------------------------------------------------------------------------------------------------
-----------EQESGVLQLFRLLKSLSGYGKSLALTVVTSQSVAVRAFETANPIAASIHGLVATLKSEYPHWRVRLLDIDRGELPSL----AELFPDND
T-ADFPLLARRDKQWFARKLIPIAFES---NDFPAYKQKGVYVAIGGAGGVGEVWSRHIIENYQAQVIWIGRRE---LDDKIREKQAKL----AAFGSKP
LYIQADAKNKASLEKALDEIR-QSYSCINGVVHTAIELQDQSLAQMSIARFRTGLFAKAETSVRLVQVFQHEPLDFVLFFSSLISFGESPGQANYAAGCT
FLDAYAQQLGKDWAVSVKVMNWGYWGNTGVVADATYRERMRQNGIGSIESQQAMAALNRLLQG--QVVGSAPSQTAHPVVENVAPEIRYSQQWQLIRTHR
TDARDALLQNLLLANSPNGRSLPVTYYHKWLDVEELWQKAYRGNPVADFFNEVIAEVGAGTSVMSLQERTTEFVRQTLSERTPANKVRLDTPFEQYGVDS
IVQVGLIQKLEQVTG-SLPNTILFEYSTTRELVDYLLAHHQE--------
>tr|S5R120|S5R120_9PROT Mixed type I polyketide synthase/non-ribosomal peptide synthetase, PedF-like protein OS=Candidatus Profftella armatura GN=dipT 
----------------------------------------------------------------------------------------------------
------------KNNVIIQLFRLIKVLEGYENDLKITIVTIQGLFICDYDEINPHHASIHGLVSSIAQEYPMWSIKAIDMINNNVINWS--VS-LWYQLL
G-VKNISIARRKYNWFFQKLIPLNFY----ISKDIYRKNGIYLVIGGAGGVGSIWSEFMIKNYEAKIIWIGRSP---KNNILQEKINNIS--IKYNGICP
IYIQADARNSNILFSTYQKIK-KDFDHINGIVVSTLSDYDLSFKEMSEDLFINILSTKHDVSLSIEKCFYKERLDFIIYFSSMISFEKPGGMSAYVSSCT
FSDAFSKKINKKWDCVVKTINWGYWNIGGGIISSALKKLIEKRGVESINKEEGMNILKLFLGNITEVLPNNISNIEKNILNDSLRNLKIPL-----KSKY
TEELNYWIIRLLFVKVNCNQAGILDKYIVWWKYTKTWKKRYKNNCICDYFNDVVSEIGAGTSKSVLMNFIQNSILNALSEIIQIDIIKLNIPFSDYGIDS
ILGVNFIQKINNDLKLKLNTTILFDYTTVDSLSQYIITNYKE--------
>tr|Q6VT95|Q6VT95_9BACT Mixed type I polyketide synthase/nonribosomal peptide synthetase OS=symbiont bacterium of Paederus fuscipes GN=pedF PE=4 SV=1
----------------------------------------------------------------------------------------------------
-----------AQRDGVLALFQLVKVLEGYGVEFGMTVITTQALATCDTERIDPTHAAVHGLVGSLAKEYPKWRLRALDIDA--RAEWP--VPGLWRLLP
H-TRGESRVWRGCEWLRQRLVALNGMPV--AKGRAYRRQGVYVVIGGAGGLGMTWSRMMIRDHQAQIVWLGRSA---KDATVRAKLDEV----ADDGLAP
DYWQIDARDADALRQTFRQVR-ERYGQIHGVIVSTLGDYDQSVAQMSEALFREILSSKLDIGVRLSQCLRDEALDFVVFFSSMVAFGRSGGMAAYSAACA
FNDTFARQLGNELACAVKVINWGYWNLGGGTISAALKRLVEQRGVRPIEAREGLCALAVLLDG--PVKAGTHSCFAN----VYQPTQPMPQ-----ESPD
AARLNLWIVRLLFVQETGRQAGIVDKYERWWRRERLWRECYKNNLICDYFNDVVAEVGAGT-RQDVAARVRELILDSLAQSIGREQIEQDIPFSDYGIDS
ILGVGFVQRLNDELGLSLNTTLLFDYTTVQRLAEHIVAEYGH--------
>tr|L8PZ43|L8PZ43_BACIU MlnG OS=Bacillus subtilis subsp. inaquosorum KCTC 13429 GN=BSI_21380 PE=4 SV=1
------------------DLPGLVLIFAENDWQIKELSDSLVDCN-LLFVCRGEKFSINNRNVLTINPAKKADYIKLFKYIQDQFMLPENILHLWSDSQD
NI--SQEGIEKQLESGIFSLLYITQALIEMKNTVKLKFQTEHKAQLP-------LHHALGAFVKTVHQEYPNFHYQIINVNHAQDM-GVDNYSDIYRKEG
DQTSQFEVRYENGSRFTKRYKSANIDGL----SQPLKRKGCYLITGGLGGLGYIIAKYLTEKWKANLILTGRS---SLTAEQSRKINDLRS----SGSHI
EYIQSDISKKDETERVFTFVKDQFG-HLNGVFHIAGVLRDSFILRKTKEEIDQVTAAKVYGTVWLANEIKKLNLDLFVLFSSTSSIFGSIGQGDYAFANA
FLDQYAAVIS-AKAQKTVSVNWPLWAAGGMNIDYEGQLMRRELGLEPLDESTGLRALEDSLCQT------------SEQLIAVKG----QKEKI---ENA
----L---NRAINSLLEQRDE-------------------K---------NERNDELKQEI---------IHYLKKLLSEELSASFIDEKQYLEKYGIDS
IMIMRLTKKLEQNIG-KLSKTLFFEYHSITELADYFLNH-----------
>tr|S0ADM1|S0ADM1_SERPL Polyketide synthase PksJ OS=Serratia plymuthica 4Rx13 GN=pksJ1 PE=4 SV=1
------------------TPPGNGTLLLVPTWSRKQVRGDVVAPH-ATLFCGEPSVA---------------K----------AMGLTNDLIFPAMDSEE
HI-------ALDFQQQALALFGRVKSLLDGRQPMLLQ-AVVGALPAP-------FSAALCGVLKTARLENGRFIGQLIELEATARA-DEI---DRLRESS
LVPEDIHIRYGGEGRQVLSWREVHSGAV----RIPWKERGVYLITGGAGGLGLIFATEIARQTRSRLILTGRT---SMNDRIQAAVSQLIA----LGAQV
DYCQLDVCDRPGVEALTASTMAKYG-AINGVLHCAGVLRDSYILKKSPEDFLAVLAPKVQGTVNLDLALAQHPLDFFILFSSTAAALGNPGQADYVTANS
FMDAYAHYRQRAQMGRSLTINWPLWKEGGMAVDDASTLMYQNTGMIAMSAAAGLQAFYQALERE------------ENQVLVIAG----DIEKL---RLT
----L---ANG-GELEEAVQQLLIREVSA----LLDVAATEIDLDLTGFANVDIPALHEAV---------QSLLMQEISALLDAADIDNDIELSELGFDS
ILTTSFANKLNRQYALELLPTVFFEYPTVAGLTHYLAER-----------
>tr|B8I8K2|B8I8K2_CLOCE Beta-ketoacyl synthase OS=Clostridium cellulolyticum (strain ATCC 35319 / DSM 5812 / JCM 6584 / H10) GN=Ccel_0863 PE=4 SV=1
------------------------------AGIGHEFKRSASNKGHVVLAVPGQSFSEGEGGIYEFEITSPDCFTMLFESLKKKGSVPEKIIIIYPDGQG
AL---PDTINESLDRGIYGLFKTIKAIMTQ-KTKAVKLLCVYGGNTTSQN-PCY--AALSGFAKTLFMENPKYTCKVLEVPDI-----SNVEEKAITELS
LNVMEFEVKYSDKCRMVKTIKEI--EKTE-CKSLPIKEDGVYLITGGTGGLGLIFAQYLAEKYKARLVLTGRS---ALTDEKKVAMTKLEN----CGAKV
QYIKADVTSRESVNKLVESVKSSFG-CINGVIHSAGVIRDAFIIKKTLEDMKAVISPKVYGTMWLDEATRSENIDFFVLFSSASSATGNMGQCDYAFGNS
FMDNYAVMRSINPNSVSLSINWPYWKEGGMRLGEETIAMMKKSGIIPLLTDEGIRAFEYGLC-----------CSPALSRLIVLK--------------G
------EAGRIKNGIKTEKQEE--LKQTIK----EN-------QPAPAVANT--NIAAGEDEKWILKEKTEAFLKEILSKQLSVDRIDSVEPLERYGIDS
VIIMGLNSELEGHFGK-LSKTLFFEYQSISELAEYFM-------------
>tr|C2NRS6|C2NRS6_BACCE Keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase OS=Bacillus cereus BGSC 6E1 GN=bcere0004_54400 PE=4 SV=1
------------------------------EEL---FYELQSKEDKVLLIKPGNTFKHLEDNIFEINPVEEEDYKKLFQYFKNISINYSNILHLWSFG--
LD---DRIVTEQLQHSLYSLFYTNRALVEQ-KMKGIVNVLYF---YPLNN-PLF--EAMSGFHKSIHLENPRIQCKTIGMNSK-----EDVLPRILNELN
CKEIEGEVRYVMGRREIKVLQKF--LPEP-VRNLEINQKGVYLITGGLGGIGFILAKYLAKEYQARLVLTGRS---KNNNTINSKLKELQS----LGGQV
IYLSSDISNENEVKKVIKCAKNHFG-NINGVLHCAGIIRDSLVWRKTEQDIENVIASKVHGTMYIDAATRNENLDFMVFFSSISGEKGNVGQCDYAFANC
FLDNYSRMRRLGRSGKTLSINWPLWKKGGISVDEQTQRFMENLHLVPLEEEQGISILKK--C-----------INTPEEQVMVLY--------------G
------DGEKLNKSQKNEISLE--GERVVL----E-------------VSKK--E----------MHTKVTQDLVRMVSDIVQKRDILTDVDLDEYGFDS
ITLTELSNNLNQMLDIHVTPAVFFEISEIT------I-------------
>tr|A0A0M9DXX9|A0A0M9DXX9_9DELT Beta-ketoacyl synthase (Fragment) OS=Candidatus Magnetomorum sp. HK-1 GN=MHK_009988 PE=4 SV=1
----QQVWQQKAIELAETSVHEKILLFSNTLMV-DDIKTFMPN---HIIVNSGDTFEHFSDIHYSIRPDEPEDYQEL---IRLSGIP-NYIIHDWSSREK
FQTDD-ASIQKALAKSFYSLFHLTQTVLTNKLSAPLCIIYVCPMNHPI-------FNSISAFAKTVHQENPMIYCKTIIIDEE-----TKLSKCLLPEML
TW-DVFDVRYVQNKREIKAIQETKIDENN--LFDSLKKNGVYLITGGSGGIGSILTQILVKNYQARIALCGRKKSLDQ--AQATQLEQ----LRKNGADI
HYFQTNLSVKDDVFSLVQQVNNQFGA-INGVFHCAGMINDSFIIRKNPADIIDVLSPKIFGTLYLDEALDQKNLDFFVLFSSISAVLGNVGQCDYAFANS
FMDHFALYRH------YTSINWPLWENGGMNVDKTIKSEMSHMGILPLSDIGGLNSLLAAIHENKSQLIP-IEGFPQKIATMKRSNQ--PQELVVHQKFE
IA-----------------------------------ESSHNNI----------------------FQQTQDLLRKVVSDETHLSKIDIHAPLEKYGIDS
IMVVNLTNRLEKIFG-PLSKTLFFEYQSLSELSEYFLSN-----------
>tr|L8JXX3|L8JXX3_9BACT Malonyl CoA-acyl carrier protein transacylase OS=Fulvivirga imtechensis AK7 GN=C900_01927 PE=4 SV=1
----APEWQVSPKSPQKPKYAQQHLVLCGLPDVDEKVQRLMPE---VQLL----------ALKPEKDRDIAGRYL-------------------------
--------------EVAQACFASLRKILGNKPQTIIQIVAPYDLQETF-------FAGLSGMINTAMLENPQLIGQIILVESQ-----LKTQE--LVERL
KYDRDTTIKYEQGIRNILRWKITANTEQQ--PAIPFKERGVYVITGGLGGLGQLFARIIQRTANSRIILTGRSAQKDLK-EKQSVLKA----LRAISDGI
EYRQLEVEDLTQVERFVNTVIDEYGQ-INGIIHSAGMIADNYILKKDDTEFDSVLRPKVAGTYNLDLACRNTDLDFFVLFSSVASVFGNIGQADYAAANG
FMNQFADYRNHLVQGKTLALHWPLWLEGGMNPDQATRELLRTTGMSPMKTASGMHAFYQALALQYGQVLV-LEGNLPQLALLEESGN--RTSIDAEV--S
NA-----------------------------------ETNHGDL----------------------SEMTREYLRKEFAEVLKLHRIDVQQPLEKYGIDS
ILALTLTTQLEKTFG-SLPKTLFFEYQTLQELTGYFVKA-----------
>tr|A9EAB7|A9EAB7_9FLAO Polyketide synthase of type I OS=Kordia algicida OT-1 GN=KAOT1_04315 PE=4 SV=1
----TQTWKETKG--EKVAFDHNEIIFYNFAQEDKTIQNNLSN---ASCS----------AFKVSSKKNTAEIYE-------------------------
--------------EVSLQIFKKVQELIQKKSQVHLQIVYNNTAENEI-------FTGITGLLKTAALENPKFSGQIILTDQ------NDAKE--ITKQL
QFNIDTVVKYENTVRYVWQLEEISLPNTQ--ENISFKENGVYLITGGFGGLGTLFVEILQQTNNATIILSGRSELTS---EKEAKLKK----LTENGGNV
AYRQLNLSDEKQTKSAIAAILKEFDQ-LNGILHTAGMTADNFILKKTTEEFTNVLQPKVIGTYNLNLATQNTDIDFIALFSSGVAALGNPGQGDYALANG
FLDHYANYQNKQQNTKYVAINWPLWKNGGMGLQAEMLENMKQTGVRPLETANGTTAFQHSLNLETSSLFL-LEGEAQKIKLLFEKPA--IEEITEETPKA
TT-----------------------------------TETTDNL----------------------VEKTIAYLRKEFSSVLKIHKIDTRAPLERYGIDS
VVAMNLTGKLEKTFG-TLSKTLFFEYQTIDELGEYIAAN-----------
>tr|W4BAM4|W4BAM4_9BACL Beta-ketoacyl synthase family protein,phosphopantetheine-containing protein OS=Paenibacillus sp. FSL R5-192 GN=C161_02755 PE=4 
-----VRWVEDRGDATAPSSSGTVMIIGNGTELEQELSAGLKGEGRVVHVRPGDQFQQISEDQYEVGGDMPGAYSQLLNMY---TDEITEIIYMSMMGSS
FYPEDLASIEARQKEAFYSPVYLVQALMSFAEEIHLNLIAEYAGHVTGREEITPHNALLMGLGKVIQQEYGHIRSKFVDVDQS------ICTEDILRERH
INGEAYAVSYREGQRYTETFTEIDLNESE---SVPFEPDGVYLVTGGTSGIGLEAARFLASSKPVKLALVGRTLLPAKEEWQDSRCTKMQGILEALGATV
HYYSADLADVVGMTEVIQDITHRYG-NINGVIHGAGIPGDGFLYRKSDDEFQTILGPKVKGTWILEKLTRDQDMDFMVLFSSGISVIGEIGQGDYTAANC
YLDSFAAWRT-GQGRRTLSIDWVSWKETGMSVEFGINGM-----FKTIPTTDGIAAMEAAMSRRLSRVFIGANYGSKHL--AALGQF---------PFRL
SDKLEAGVKRSK-EIADQ----GAQHRPNRTIPQ----EKHTGPVDL---------SG---NEEGRYSETEQQVARIYSEILGYQEINIYDNFFDLGGNS
IMLIRMHERLNEEFPGKVKIAHLFAHTSIHKLALHVNQG-----------
>tr|A0A0Q4QSK7|A0A0Q4QSK7_9BACL Uncharacterized protein OS=Paenibacillus sp. Leaf72 GN=ASF12_16670 PE=4 SV=1
-----PVWTPEERSS-GADLAGAVLLLGGRSDSHKQIAEGLEAAQAIINVSLGEEYIQHHSGSYTIRNTQ-DDYIRLFENI---GATLTQIVHMLSLDTI
APIDRVEQLDESQKHGLYSLFYLYKAWLHGKQPLDVVLLTDNAQEVSGVETIRPEHATAIGFGKVVTKEHPPFNVRSIDMDQD------TDAVQLNEEYG
AGSSPYGVAFRANGRYVEQFAQMELDRIA---DEPVTEQGVYIITGGTGGIGLEVAKSLAAASSINLILVNRSAMPERERWTDLLISKINAIREAAGAQV
KLYQANISDEPELRAMLSDVRSVYG-KIDGIVHSAGVAIDQLLKDKQANVIRDVLLPKVNGTWLLNKCTEDDQLDFFAMFSSVATIYYGSTQSDYVAANA
YMDSFTHYRS-KQGKKTLTINWTTWKETGMAKNSGVATI-----FQTLPTASGIEGFTALLNKQSRRALIGSNYDRLGI--LLLEKA---------TVRL
SEPLQRRLDYHK-QLASA----GSTSNKAAKPKG----AAKSGEVQL---------TG---RDGAAYNETEKTIAAVCQNALGYAEIDINDNFFELGADS
ILLMRIHAELDKRYTGLLSVADMFEHSTISKLAEYIVEQ-----------
>tr|A0A0B5P0D7|A0A0B5P0D7_BACTU Beta-ketoacyl-acyl-carrier-protein synthase II OS=Bacillus thuringiensis GN=fabF PE=4 SV=1
-KSDQPYLVCAPVWKE-EKLVGDTLILSSNLSLYEEWRKRIGSDRNLVFVTPGTKFTELGDLKYTINPSCYEDYEKLWHSLKRQDVYPDNLIQFYPVVY-
----MVQSFIKEMKTRSIRLLYVYENLEDSSYPYY---------------------AGIKSLLKTIVLEHNNFKCSSVELDSKMTQRCMLELFALAKETS
RK--VKEVQWRGNNRYVGNLVEHDIVSSRESLNVGFQKEGVYIISGGLGGIGLLLCKHLLTAYQAKIVVFGRSAL---NETKQRALQDVMDN----GGEV
IYMCGNVSNKQDVSLIIKETK-QRFGKINGVFHMAGVIRDNYLMKKTESEIQEVIEPKILGSIYLDELTKEEPLDFFVLFSSISGLLGNIGQCDYAFANN
FMDHFVEIREQRRRTNTLSINWPLWEEGGMNVDSEIKQAIKNTGMDALASKDAFTILERGLRSKLNIFTGDLEKIKS-----------------------
------------------------------LFNIQNKSILVSNEKNITLEEMNVSRNDISEENLK--TLTIQLLKEIISKEIPIKDIKEKLPMDRYGLDS
IIILKVGNELEDYFD-DLSKSIFFQYETIFELCEYLIQN-----------
>tr|A0A0K2FAE1|A0A0K2FAE1_9BACL Polyketide synthase OS=Paenibacillus peoriae GN=ABE82_16365 PE=4 SV=1
-WTAPETLMLEPVWEE-QAIAQQHLVILCEP----GYISG----EIIESQMNGVQCLILQSEEKSIRTYATQVFEAIQHILKTESKG----------KT-
----LVQLVVP----------------VQDHQQVF---------------------SGLSGLLKTAWLENPVLVGQLIEMDVEQDPAGMINIL---QENS
RGSIEPHIRYQSGRRHVAVWTEIKAS--GEAISIPWKDRGVYLITGGTGSLGLIFAEEITRQRDTALILVGRSPL---RGDTKARIEEIEAL----GARV
VFRQADVADKRAVEVLIRDIQ-EEFGKLDGIVHSAGMVSDNFIIKKTREELQNVLAPKVTGLVNLDQACKEIPLDFFILFSSVAGSLGNIGQADYAAANA
FMDAYAKYRSTLVERETISVNWPLWKEGGMRIDGETEK-IMEMGMFAMETGAGIRALYQSLASEKNVLEGHASQLRE-----------------------
------------------------------TLLQQPSLNQAGDASS--MIRESEMGSVIGQDLLA--EKAANYLKQLLATRLPARQIETDAPMEKYGIDS
IMIKQLTRELEKTFG-TLPKTLFFEYQNIRELTQYFLKV-----------
>tr|A0A0F6EP06|A0A0F6EP06_PAEPO Polyketide synthase OS=Paenibacillus polymyxa GN=LK13_03570 PE=4 SV=1
-WTLSETLMLEPVWEE-QALVRQHLVILCEP----THISG----EMIESQMNGVHCLILQSEEESMRTYAAQVFEQIQQVLKTQSKH----------KT-
----LIQLVIP----------------VQDDRQVF---------------------SGLYGLLQTAQLENPTLVGQLIEVDMEEDAADIINIL---QENS
RNFMSSHIRYQWGRRYAAAWSEIKSS--QEVDRIPWKDKGVYLITGGTGSLGLILAEEMARQKDVALILVGRSML---RGHIKARIEEIEAL----GARV
VFRQADVDDNRAVEDLVRDIR-EEFGKLDGIIHAAGVTSDNFMIKKTEEELQKVLAPKVTGLTNLDQACKDIPLDFFILFSSVAGSLGNIGQADYAAANA
FMDAYAGYRNTLVEQKTLSINWPLWKEGGMRIDSETEQ-IMEMGMFAMGTDTGMRALYQSLASGKDVLEGHASQLRE-----------------------
------------------------------TLLQQPSLNQVEDASS--MIMESRKEPGIAQDLLV--EKAANYLKQLLATRLPARQIEADAPMEKYGIDS
IMIRQLTRELEKTFG-TLPKTLFFEYQSIRELTQYFLEV-----------
>tr|E3E975|E3E975_PAEPS Polyketide synthase OS=Paenibacillus polymyxa (strain SC2) GN=pksR PE=4 SV=1
-LTIPETLMLEPVWEE-QAPAQQHLVILCEP----APISG----EMIESQINGVHCLILQSEEESMRTYAAQVFEQIQHVLKTQSKH----------KT-
----LIQLVIP----------------VQDHRQVY---------------------SGLYGLLQTARLENPGLVGQLIEVDVEEDAAGLINIL---QENS
RNSMDTHIRYQWGRRYAAAWTEIQSS--WEAGRIPWKDSGVYLITGGTGSLGLILAEEMARQKDALLILVGRSVL---RGHTKARIEEIEAL----GARV
VFRQADVADKRAVEDLIRDIQ-EEFGKLDGIVHGAGVTSDNFIIKKTGEELQKVLAPKVTGLINLDQACKDLPLDFFVLYSSVAGSLGNIGQADYAAANA
FMDAYARYRNTLVEQKTLSINWPLWKEGGMRIDREMEQ-IMEMGMFAMKTDTGMRALYQSLASGKDVLEGRANQLRE-----------------------
------------------------------TLLQQPSLNQAEDASS--MIMESRKESGIGQDLLA--EKAANYLKQLLAARLPARQIEVDAPMEKYGIDS
IMIRQLTRELEKTFG-TLPKTLFFEYQSIRELTQYFLEV-----------
>tr|A0A0K0PDE8|A0A0K0PDE8_9DELT Malonyl CoA-acyl carrier protein transacylase OS=Candidatus Entotheonella sp. (ex. Theonella swinhoei) PE=4 SV=1
-SKAIGTWMSFPVWKE-KSWSAQRTVMLIEM----EWVSD----RLIESQIEGTTCVHLTTQANSLQDISVQVFERVKALMEAKLRG----------SI-
----LIQLLVP----------------HSGETLLF---------------------SALAGILRTAHLENPALLGQVIILEPSETQEGVIDKL---QRDS
SCPEDALIRYQQERRQTMAWQELPMSEREQAVQVPWKEGGVYLITGGLGGVGFMFAKHLAQHRSVSLVLTGRSEL---DEQRREQLKELEAL----GARV
DYLSVDVSLKEAVERLIDYIE-SERGSLTGILHSAGVIQDNFIIRKAVREFQSVLVPKVDGVIHLDQATQALNLDFFVLFSSLSGINGNAGQVDYACANA
FLDAYAHYRNRLVAINTLSVNWPLWKEGGMQIDPQRAEAMFQLGLVAMETSRGIQALIHGLSSGQSVVAGDLERLKV-----------------------
------------------------------AHPSRPSSPPSQ--MD--REHNVIGENELDANALA--SRSIHYFKNLIASKIPAHRIQNDELLELYGIDS
IIIMQLINQLERDFG-PLSKTLFFEYPTIEEVNQYFVDS-----------
>tr|A0A0K0PEG6|A0A0K0PEG6_9CYAN Malonyl CoA-acyl carrier protein transacylase OS=Planktothrix paucivesiculata PCC 9631 PE=4 SV=1
-SKAIGTWMGFPVWQE-KPLSAQHIVMLFEM----EWFSK----QSVESQIEGATCIHLTTKTKTLQEISVQVFEQIKGVIYEKNKG----------VT-
----FIQILIP----------------SSGEMSLF---------------------SALTGLLRTAHLENPAILGQVILLEASETQEGLIDKI---QRNS
HCPEDTFIRYQQEKRQIISWQELSVS--EQAIPIPWQEGGVYLITGGLGGLGFIFAKHIAQQRKVVLILTGRSTL---DERRHKQIKELESL----GARV
YYRQVDISQKQETERLIKNIE-NDIGSLKGILHSAGIIRDNFIIRKTASEFQSVLAPKVDGVINLDRATKELTLDFFILFSSLAGSIGNVGQVDYACANA
FMDAYAHYRNDLVATKTFSINWPLWKDGGMHIDPWTENAMLQSGLVVMETECGIQALIQGLSSGQSVLRGDLERLQI-----------------------
------------------------------LQQTHLSSLPSQ--ID--IGQEGIPENEFGEQELE--ARSLHYFKNLISSKIPAHRIQNDELLEVYGINS
IVIMQLTNELEQVFG-SLSKTIFFEYPTIEEINQYFVAS-----------
>tr|A0A0A1F9G3|A0A0A1F9G3_9BURK Malonyl CoA-acyl carrier protein transacylase OS=Collimonas arenae GN=LT85_0342 PE=4 SV=1
DWHYAEPALPTP-----VA---SVALLGAESPLSAALTERFKLLGTVQGWQTPADVGQVDLLI---------------------ALTPDFQRLTWLAQRL
A----------GGKT-------------------RLVVVTRNAQQ--ADAATDRHAAMTAAAALCIGQELPELALRQIDLCEAAAALNPRQVSALANECL
--ANGPSVVLRDGRRRIAVASPLTAPAMTSASTSAWRANGVTLITGGFGGVGMAFARHLAQSSQARLVLLGRQLP----DEHDPRLQELR----QLGAQV
LPLAGDISQPGVAESAVQAALQHFG-QLNSVIHAAGIAGTAAQRPTDNVESAEILAAKCSGTSYLAAALQPLADHVVL-CSSLSTVLGGLGFAAYAAGNR
WLEVCAEQQNRNGVTPWLALAYDGWRFDAAAGAEPT---L------S--AADAI------RLTDQ-ALALGLVG--------------------------
---------RVLVSAG-RLQTRL-----------ERWTSQAADMADTAYLDTYDD-------------PIEASVAKALAETLALPGIGPDDDFFALGGDS
LIATRVIAKLRSATGLPLSVGLVLQAPTVRLLATAIAA------------
>tr|A0A0B9GZ19|A0A0B9GZ19_9GAMM Uncharacterized protein OS=Photobacterium gaetbulicola GN=RJ45_08770 PE=4 SV=1
DWFYRQNWHPLE-----SQ---STLLLGDDKGLAQQLTDLLQAQQHVMRAHSGAAFGQLEPLAYTVRPDSGDDFDALFAQLKAAGTMPDTIIHFWQHQSL
P----------DQVDVDRLVESQRLALGRAQAQTKLLFVTCHQQAVLEEELVDPFKATLLGASKIIDVEYDGVVSRSIDFASAPTDESHKQAAHILMRCS
--APEPSVAYRYGLRFVPAYGRV------TQEANPLKLGGTYLIAGGLGGMGLAFAQYIADRVPANLVVITRRFP----HRHIEVLQQLE----EKGCQL
LVASAELDDLDAMAEVISQVHQQFG-RVDGWIHAAGVVDEAGVIQSTPAGLRQGMRAKVRGTLVLDRLLSQDSDFVLL-CSSLSVVTHQIGQVAYASANE
FVDAYATYKQRTSTTAVTAVDWDDWRDAGMSKRSRDKAQLSDELTLT--VAEGQ------EIFAR-ALSCGLE---------------------------
---------RVIISI-----RDL-----------HSWQRTVGGLHPQSIALMTCD-------------ELKSALASLLKRMLGVSEITPDDDFFRLGGDS
LLVIQLVNTIREQFDISLGLEEIMARPALADIEALVLD------------
>tr|L5MQ59|L5MQ59_9BACL Beta-ketoacyl synthase family protein,phosphopantetheine-containing protein OS=Brevibacillus agri BAB-2500 GN=D478_18964 PE=4 S
------------------------------------LVELQAREADVIEVALGAAFEKGG--DRQYKIGSADDFPRLLQELAHR--DIRHIVHCMGMTEE
K-LACADDFHEWENRSVYSFCQLVCELLNYHQEINLYLLGDQAFSVTRREALNPQHAVLFGLAKVVAQEYPQLKCRCIDLDSA---TAP---STLWAEWE
AGEEDFQVAYRENVRYVERLEAQTLQAAEPQ-AVSIRENGVYLVTGGLGDIGLQVAHYLGNKQPVHLCLLARSAFPE--REQWAEIVREQALAEDSGSSV
EVHTVDVADERRLAQTIRQQY---G-AIHGVFHCAGVAGEGLLINKGRAKIAQVLAPKVVGTWLLDRYTEQDRLDFFVLFSSVTSLLGGLGQADYTAANA
YLDAFSDYRQ-AKGRQSVTINWPAWNDTGMAARYRIQ---KEASFCGMHPDKAIGILDAVLRRKL-------------ARVIVGELNEAHFQTHRYPLFA
----------ISPEIRSMF------ARPVAWEPET-----ADATPLAPMLTGRTDH---------TYSAVETRLAAVWQKVLGIPEANVYQSFQEAGGNS
ILATSLVKEIEQLYPGRINIATLFAYPSIAKMAEYLENKPS---------
>tr|W7YFR5|W7YFR5_9BACL Malonyl CoA-acyl carrier protein transacylase OS=Paenibacillus pini JCM 16418 GN=JCM16418_316 PE=4 SV=1
------------------------------------IERLRNKGESVVIARFGHHFEQTGA-DSCIVNGSEDDFDQLLHWIGAG--EISRVIHMASPSNR
S-NLSWEQFEQSQAQGTYSLLFLVRSLIHCQQRIDISLIADHVHHVNGDEPLNPEAGALFGLGKVVHTEYDNLRCRAIDMDAA---TGP---DDILEELY
LEREYYNVAFRSGNKYMERFSKAELSDYAEM-PVKVKDEGAYIITGGTGALGLEAAKYLVERGAAHIALVSRAPLPV--REDWNSLLEGELTAEAKGAVV
SCYSANVSDIHAMNQDIRSQY---G-LIYGIVHSAGVAGDGFLINKSLDVFNEVYLPKVYGTWILDHLTQGDPLDFFILYSSGASLIGEAGQGDYCAANS
YLDAFAAYRS-ARGQRTQTINWVKWRDIGLAVNKGSN---HD-GYKLLATEIAMKALDEILHRDI-------------TQIMVGQMNLEQYLSMMELFFK
----------LAPEIEAVV------KRSVSEQSRI-----LKNISVTIQMSGREGS---------SYSEVEMTLATVYQEVLGFKEINVFDNFFELGGNS
IMLNLMYARLQKLYPGQLKLTDLFTYTSISRLAEYLTNNNN---------
>tr|A0A0N7FMV9|A0A0N7FMV9_VARPD Var4 OS=Variovorax paradoxus GN=var4 PE=4 SV=1
-----------------------LLVLGDSRSLTGHLVRQLRAQGTVVLAERGTAFARTAHGHWTLRPGARDDHARLQTEIAADFGAITGIYHLWSLDEA
LPA--QQPQAELLERSFFSLLALVQSLDAGDRTLPLAVVANQLEDVTGTEPLCPEKATLRGIGKVIGQEYPRVHCRVIDVVAPESDAEGRLVAQIVAEAA
AAEPEPLVACRGAHRWIKTYEPATLTAAA---QPRLRREGVYLVTGGLGGVGLALAKHLAVQWQARLVLLGRTAPPALKARLQ-QLLELEA----LGAQV
LTVSADVSDADAVRAALAQADARFG-PLHGVVHAAGDAGGGMMAGRTRAQVDTVFATKVRGTRVLFDALRGQPDFALL-CSSISSVAGGLGMSDYAAANA
YLDAVAVAHERLGAFPVFSVNWDAWRGLGMAAHMDVPD-----D-------------------------IGMDGP-------------------------
--EGARVFERIVNGITTDLTTRL--------GP------LDNGMLDL-----LGDEAPGATPFVAPQGEVETALAALWTERLGIAPIGVDDNLFELGGDS
LVAIQLLSRVRKRYATELHPSEFFKAPTIAGLAARL--------------
>tr|B2HFX0|B2HFX0_MYCMM Polyketide synthase and peptide synthetase OS=Mycobacterium marinum (strain ATCC BAA-535 / M) GN=MMAR_3099 PE=4 SV=1
----------------------------------------------------------------------AVQLARLWGA----KVFVTASRGKWDTLRS
MG---F---DDSRIGDSRSLEFAEKFFATRGRGVDVVLNSLAGEFVDASLRLA-PGGRFIEMGKQIAVEYPGVIYEAFDLIEA----GPARIQPMLGQLH
TLFRCAPAAY----RFVSQARQIGKVVLTPTQISDAVAAGTVLITGGTGMVASVLARHLVSSYVKHVVLASRRADA--TAGVAELVADLAA----AGAAV
AVVACDVADRAAVTRLLDHV-STCHPPLTGVIHAAGTLDDAVIASLTPDRVDAVLRAKVDGAWNLHEATRHLGLSMFVLCSSIAATVGSSGQANYAAGNA
FLDGLAAYRR-AGGLPGMSLGWGLWEQSSTMAHLSDRDRIRRIGLAAISPEQAMQLFDAALAVGQPTV--LA----AHLDHAVLA--NHTLSSTLPPLFS
---------TLIKRPLR----RLV---------------DNDTPSSTAGFAQRLYG----LKPEKQQDLLVDLVCTQAAAVLGHPDLNPASTFQNMGFDS
LTAVELRNRLKTVTGLGLSPTLVFDHPTPTALAGLIAEL-----------
>tr|D7F1A4|D7F1A4_9CYAN Mixed NRPS/PKS OS=[Oscillatoria] sp. PCC 6506 GN=cyrB PE=4 SV=1
----------------------------------------------------------------------LEDWKQLWKR----VTNIQEIVHCWSMVS-
TD---L---EATLLSCGSTLHLIQAL-ASYPETPRLSLVTLGAQAVNE-HHQNVVESALWGMGKVIAIEHPELGVVQVDLDPN----TTVEAQVLKGELF
AIARPREIAFREQRRYVARLSPLARPTRGKQEPLTFRDDGSYLIAGGLGGLGLLVARFLV-THARHLVLVGRRGAR--E-EQQAQLSELEQ----LGASV
TVVQADIADAAQLTRSL-----ATYPPLRGVIHAAGTLNDGILQQQSWQAFEEVMAPKVAGAWNLHTLTKNQPLDFFVLFSSATSLLGNAGQANHAAANA
FLDAIASYRR-HLGLPSLSINWGTWSEVGIAARLGLDKLSSKQGEGTITLAQGLQILDQLLKDEVHQV--GV----MPIDWPQFL--ARQ--LTPQPFFS
---------DVMKNIDTS--GKLT---------------LSRSQAYGHNIRDQLEK----APPKEGMTLLQAHVREQVALVLGIDLAKQEVGFFTLGMDS
LASVELRNRLQASLGCSLSSTLALDYPTQQALVNYLADE-----------
>tr|D6MS58|D6MS58_9NOST Mixed NRPS/PKS OS=Aphanizomenon sp. 10E6 GN=cyrB PE=4 SV=1
----------------------------------------------------------------------IEEWQQLLNR----VPNIQEIVHCWSMVS-
TD---L---DRAIFSCSSTLHLVQAL-ANYPKNPRLSLVTLGAQAVNE-HHQNVVGAALWGMGKVIALEHPELQVAQMDLDPN----GKVKAQVLRDELL
ARKRPHEIAFREQTRYVARLSPLDRPNPRTQEALTFRDDGSYLIAGGLGGLGLVVARFLV-TNARYLVLVGRRGAR--E-EQQAQLSELEQ----LGASV
KVLQADIADAEQLAQAL-----VTYPPLRGVIHAAGTLNDGILQQQSWQAFKEVMNPKVAGAWNLHILTKNQPLDFFVLFSSATSLLGNAGQANHAAANA
FLDGLASYRR-HLGLPSLSINWGTWSEVGIAARLGLDKLSSKQGEGTITLGQGLQILEQLLKDEVYQV--GV----MPINWTQFL--ARQ--LTSQPFFS
---------DAMKSIDTSV-GKLT---------------LSCPQGYGHNIREQLEN----APPKEGLNLLQAHVREQVSQVLGIDLAEQDVGFFTLGMDS
LTSIELRNRLQASLGCSLSSTLAFDYPTQQALVNYLANE-----------
>tr|A0A0F6EWR6|A0A0F6EWR6_PAEPO Uncharacterized protein OS=Paenibacillus polymyxa GN=LK13_18645 PE=4 SV=1
----------------------------------------------------------------------EADYLQLMSELRQRNQRLNGIVHLWTCTDP
PLIPET---VDVLESGVYSLYFLTKALLQGLHELDLRVVSNFTQRISDEQ-ISPEKSAIHGLVKVISQEHPQLQCFGLDVDTI----HHTREQVLIMELQ
ENK--TDFVVIRQERYIQGMARLESDLVSARRSVTIRPGAVYIVTGGAGGLGLEVCRYLS-QQPIHLVILNRTELP--EKEKLSAFVDMEK----HGSQV
HYYAGDVSDFRQVQLIFEDV-QARFGPVKGVVHCAAASGDTPLEVQNRDDFGKVLCPKIHGTLVLDKLLAEQETDFFVLFSSVASLWGGAGGGDYAAANT
FMDAFSAQRN-MRGQTTLAINWYAWEGLTGP---CMDY---------MPVPDALAAFHMSLSCPQVAI--GKFDTQKLREWAPMM--KIQ--LAPDMLTD
---------R-HRAVP-----QST----------------APSFVKVTDVKVSLKG----K-PTEPYTELEQQIAQIWAEVLGY-EIDVSQHFFEIGGDS
LLILKVLSLLNERVDPEVEAGDLFSYGTVSQLAQFIEGR-----------
>tr|A0A0K2F5Z0|A0A0K2F5Z0_9BACL Uncharacterized protein OS=Paenibacillus peoriae GN=ABE82_05785 PE=4 SV=1
----------------------------------------------------------------------EADYIQLMNELGQRNQRLNGIVHLWTCTAT
PSTQET---VDALESGVYSLYFLTKALLQGLHELDLRVVSNFTQRISDEQ-VSPEKAAIHGLVKVISQEHPQLQCFGLDVETL----HHTNEQVLIMELQ
ENK--TDFVVIRQERYIQGMSRLESDTVSPRRSIAVRPGAVYIVTGGAGGLGLEVSRYLS-EQPIHLVILNRTELP--EKSKLSAFADMEK----HGSQV
HYYAGDVADYRQMQHIFDDV-QARYGPVKGVVHCAAASGDTPLEIQNLDDFGKVLRPKIHGTLVLDKLLAEQETDFFVLYSSVASLWGGAGGGDYAAANA
FMDAFSAQRN-MQGQTTLAINWYAWEGLTGP---CMDY---------MPVSDALAAFRMSFSYPQVAI--GKFDTQKLREWAPMM--KIQ--LAPDMLTS
---------R-RRAVA-----KST----------------ALSSVEVTDVKVSLKG----K-TTEPYTELEQQIAQIWAEVLGY-EIDVGQHFFEIGGDS
LLILKVLSLLNERVDPEVEAGDLFSYGTVAQLAQFMENR-----------
>tr|S0FMW6|S0FMW6_9FIRM Polyketide synthase OS=[Clostridium] termitidis CT1112 GN=CTER_0901 PE=4 SV=1
--------------------------------------------------------------FFTVNPGNSAHFKKVLE-----NIPEVNVLHLWNCQQE
CCNPQENDTL--LEQGAFSLIHLGKALAE-RAGKSRVMVVTNRMSDTSQNPHQFMAAAL-GLAA--DQEGIELCVLDLDMAEYP--TGKELLEAAVRELN
SGPDESMAAVRKGCRYVRKLQKMDE--SNQQQEVEFIDGETYLVTGGTGPVAGEICKVLAGQAKLNLILTGRKPLPGVSSDKLEVLKSIE----QAGSKA
AYYPVDVNDPEQMKELIQTVNREWG-PVNGVVHAAGLWDASSFQSKELDIIKKVLQPKVQGTIITDLVTRDQPLKFFAALSSVSASRWSAGLGDYAAANA
FLDGYTYYRN-SVPGKTVALNYSLWAEKGMVQKFATLLAVKAQGLNPLKAETAAAAFLPALRFKQS-VVHILDLIPVTPTLPVIEKT-------------
------AF------------EK---------------------------------SFSKGNSV-LPVKNVREQVLKLIAGYLGIEQLDISANFMEIGLDS
IGATRVISDISRLLNMELYPTLVFEYQTPEELIRYIENT-----------
>tr|A0A0A0NIE5|A0A0A0NIE5_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces rapamycinicus NRRL 5491 GN=M271_21620 PE=4 SV=1
--------------------------------------------------------------RFGLHPALLDALHTMAVA----GLPSLSWVHRWLEDDR
LASSRLSRGVASEHPDRFVLLRT---A-V-GAGHPHLALRHGE--ADGDSAWRLDTSSL-GMYPGPGDR-VFGLLPDADLAGLG--SLREFLEMMLSELM
SLREGDVRRAREAFRFMG-QARHVGK-VVLTVPVPLDGRGTVLVTGGTGVLGALVARHLVERGVRRLVLTSRRGLAA---GAEELCAELS----ALGAEV
SVVACDVADREALAEVIARIG-----DLSVVVHAAGVLDDAVVESLTPERVEAVLRPKVDAAWHLHELTRGMDLSAFVLFSSASGTLGGPGQANYAAANS
YLDALAEYRR-GQGLPAQSLAWGPWEQVGGGMAGADVRRMARSGLVALVAEEGLALFDAAERYASAVVPARLDREALRDSVPTLLKG-------------
-------LVTSTPNGARSLADR---------------------------------L--AGMSVEEQQRILLDLVRTEVATVLGHETLDDTQTFKELGFDS
LTAVELRNRLNAATALRLTSTLVFDYPTPIALVEHLRTA-----------
>tr|D7C2B7|D7C2B7_STRBB Type I modular polyketide synthase OS=Streptomyces bingchenggensis (strain BCW-1) GN=pks3-1 PE=4 SV=1
--------------------------------------------------------------SFGVHPALLDALHAVSFV----DLPALGLIQEWLADDR
FADSRLTRGIASEHPGRFLLLPA---A-L-ASGEPQVVVRDGV--MATGAPWRLDSSAL-GMYPGVGDR-VMGLVAGSDLAGLS--SLRSFLEMMLVELM
ELEAGDVRRARDAFRFMS-QAKHTGK-IVLTMPREWEPEGTVLITGGTGGLGSVLARHVVGRGARHVLLTSRRGLDA---GAVELRAELA----ELGAEV
SVVACDVADRDAVAGVLASIPVEY--PLTAVVHAAGVLDDGVVGALTPERLSAVLRPKVDAAWHLHELTRDLDLAAFVVFSSVAGSMGAPGQANYAAGNA
FLDALMMRRR-AEGCAGQSLVWGPWAQD-GGMTGADVHRMSAAGLPAISAEQGMALFDAATALHDAMVPVPLDLTALRGEVPGLLRG-------------
-------LVRPTRRAAADLTRR---------------------------------L--AGLRGADRVQILVDLVRAEVASVLGYDAVEIRREFRELGFDS
LTAVELRNRLNTATGLRLPSTLVFDYPTPAVLADFLVAE-----------
>tr|C5BJI2|C5BJI2_TERTT Modular polyketide synthase, type I PKS OS=Teredinibacter turnerae (strain ATCC 39867 / T7901) GN=TERTU_2203 PE=4 SV=1
----EPQWLQVPPAPINDERAGVTLVLCEPFEHADERSFADGTKGPVLWARAGSTFTVEPNVHCVWNTTSDNDYVALANWLREFNRSSTETV---IYVRN
GLDNA---------RLGFNLLDLMRAWYKQKQPVNTVFLHSE--------SHYSDACAVASLAKTAALEFPAFRLKSLEIDTS--LNDISTLQTAWSESH
-LDSGVHVRYADGARYEKRMQPCV-PAASVNQLKNFRNGGAYVITGGLGGLGIIFARYLATHYKANLVLVGRRELDRAATTICDEIAD-------CGGRA
IYMSADISETTHVSAVLHKTRESFG-ELHGWIHSAGVIRDALLPFKTRDQISEVLTPKVSATKALHQALRNQTLDFVLLCSSVSAMLGSKGQADYSAANG
FMDGFAEAVS-HPAQPWISVNWPLWKDGGMQIAEKDLDVLQAAGLDVLTTDAGMQTFERAVIGS-TATVLEMPGDL----------------AKFITRFE
------QVENQFPALAAT-------EEPARAQVAERLELQSINPA-SAATHQKTVVS----EDF------TPQLRAILSELLKLDDIVDDEPLDSYGIDS
VQTVSLLESIEKAFDIAISVIEFSELNTLQKIADYILGQ-----------
>tr|A0A0C5V8V4|A0A0C5V8V4_9GAMM Polyketide synthase modules-related protein OS=Gynuella sunshinyii YC6258 GN=YC6258_03739 PE=4 SV=1
----ASRWCETPLPISASDGEGIILAFVDPADAVIN------NNQNIYRVVPGTTFSTEQ-QLITLDEHQDSHYVALVEYLREICKTRQSTI---LYQPR
SGPDG---------RHGFCLLDLMRAWYKQKATVTALFLYQA--------DQYADACAVTALAKTAMLELPTFRLKALAVSET--ADI---WSNGLREST
-SGSGVHVRYDGQRRYEQRTLATV-PTGAH---GAFKHHGSYVISGGLGGLGILFARHLLQHYQARIVLVGRRPDSAEIQMQCQSLQA-------LGGTV
AYMSADVCETADLQRIIATA-RQAG-NLNGWIHCAGVIRDALLPFKQPQQIQEVLAPKVTAVEQLYQALQGQTLDCVVLCSSVSAMLGSKGQADYAAANG
FMDGFAEQVS-SPAQPWISINWPLWREGGMQIADSDIAVIEQAGLAVLDTETGLAMLEHAVSCG-ASQYMAMTGQQ----------------EVLTRRLA
------MVERQMLPAESA-------HNPPVATMATFAEMAEIGIT-DISIADRGVDS----TVI------QRQLRQLLSDILKLDDISVDEPFESYGIDS
VQTVTLLEQIEARFQLTLSVSEFSDLNTLEKLAGHLAAE-----------
>tr|A0A081NVN2|A0A081NVN2_9BACL Uncharacterized protein OS=Paenibacillus sp. MSt1 GN=ET33_22700 PE=4 SV=1
----TSKWREEACGP-----EAKGLLLNG-ESLADW-MRGELGEEVPFRRLTIA------QDPD-R---YLEA-------LQEVKASGFQILV-PAVRPG
G--------------EDLGLLVLAGALIRFKEPIKILYAGESMS-----SEALPALYAAGGLARTLKYEYPRLHLEVAAFTDR--FENCGLLEELFA-SA
-PAPLHEVRYVGGTRQLREMVTVA--GGLQKQAYALRQGGVYLIAGGTGGLGQIFSDYLAKEY-AKVVLLGRREQDERIAAQLDRLAS-------LGGSG
LYIRADLGDAGQVRAAVEQARATYG-SIHGVLQGSGLIEDSFILRKTTESFEKILQPKLAGTLHLDDATAGDELDFFVMFSSIAALMPNQGQCDYSSGNS
FMDAYAAHRQ-QLVGLSLAINWPLWANGGMTVEPEEKEHWKVFGMQPLETPQGLVLLREALHLG-FAHIVGIEGDQ----------------MKINQHFG
------IRKKA---------------E--------------------------LDVP----TMI------RRDLYSILAQALHLAEIGAGQQLQQLGVAS
LSLLQIANLISQYFGVDFKPPLLFEHGTSQQILDYLLQD-----------
>tr|U1ABU6|U1ABU6_9NEIS Uncharacterized protein (Fragment) OS=Pseudogulbenkiania ferrooxidans EGD-HP2 GN=O166_00110 PE=4 SV=1
-----------------------------------------NAGAQVASATAASGYRRAEAGCYELDMASDADFDRLLDDLDKDGLRPRAVLHLSA----
-----EGEISGQLDAGVHALHSLCRTQLRRPGAGALRILAA-VRGV----LPTH--AALAGYLRSLTLETPRIVIEAEAAATTDELAAIALAELGDADWR
----GDEVRYGPKARQVRTIERADFAAA--RSGALIRQGGVYLITGGLGGLGYLLAEHLARACGAKLALSGRSAADENTE---RRLAHL----RACGGEA
VYLQADVAERGQVDALIAEILTRFG-RLDGVIHSAGAHRDAYAVNKPREDMDAVLAAKVLGTVHLDRATRDLDD-LFVLFSSIAGVAGNAGQCDYAYANR
FLDAYAEARAARSSGRTLSIDWPFWADGGMRIASVDLELLERAGIHPLPTALGLRCWDDFLAS-------------GLTQGIALYGE--A--DRLDASLA
---------------------ARPRASA-----------SQPAAASADLG----------------QEAVEAYLKRLLSGEIREERIDSDERFDAYGLDS
VMVNRLNAELERDLGA-LPKTLFYECATVAELAGYLRRE-----------
>tr|A0A089LS47|A0A089LS47_9BACL Uncharacterized protein OS=Paenibacillus sp. FSL R7-0273 GN=R70723_17130 PE=4 SV=1
-----------------------------------------QDGQLSNHAQGRGHFKKIDAGHYRINPSLAGDFGRLAAECGLTDETRLRIVCR-G----
-----EGGLKE-IEREIYPVFQLCKWLSAYRHEARLCCFYQK---S----AAEY--SALAGFFRSLTLEHPKLVIHCT------G--DTPLAFILKDELA
GSDGTPEVKYEDGMRFVRQLVPMQPVSP---QEPKLALGGAYMIVGGMGGLGFIFAKYLASACQAKLVLCGRSPNAD--G---AKLDEL----KALGAEV
TYIQMDLASPVSAAQAVRTAKAAYG-RLNGVFHCAGVVRDSLWGKKELTEIEEVLNPKVYGTVHLYEALAMEEE-LFVPFSSSTSLIGNIGQGDYAYANS
FLDHYVALMNGRLGRSDTVLNWSIWQNGGMQIDSATGELLNKFGMRPMSDSEGIQAFGYSLAL-------------NEPQVMAAAGD--R--DKLIGAFT
---------------------RSSRRESIRSA----EKQPAPAVSRQAQV----------------P-QLADALIGIMAGILKRSEISRDSDLAELGFDS
ISFTELSNAINRAFSVEITPTLFFEQSTPEAIAEAVYEE-----------
>tr|A0A089LBI9|A0A089LBI9_9BACL Uncharacterized protein OS=Paenibacillus borealis GN=PBOR_19435 PE=4 SV=1
-----------------------------------------QGGLRVEHAQGKSSYKSLAVNQFQIDPADPESYTRLAEACGIAEDTKLQIVYL-G----
-----ARTVRE-VAQDVYPVFHLCRWLASFRIPVRLFCIYRD---T----VAAY--SALSGFFRSVALENPKLLINIK------D--HSRLNLVLEQEFS
GSHSEHEVKYEAGSRYTRQLITAQPPRD---RTRQLKARGVYMIVGGLGGLGYKVAEHLAENYQARLVLCGRSPNGD--P---GKLERL----NSLGADA
VYLSMDLADAKAVELTVAEVKNLFN-QLDGVIHCAGVIKDSLLVKKNMADIADVLSPKVYGTVYLYRALSRENELLFVPFSSSTALVGNIGQSDYAYANS
FLDHYVALMNEKRGRSDTAVNWSLWENGGMQVDSGTRELLSRFGMCPLSDEQGLLALEDSLSF-------------RQDQVMAVSGD--K--EKIIRTFT
---------------------GQVREASRQIRQPGSFTAAAAVPADTGVS----------------H-QLEEALIGIMADILKRSEVSRDSDLSELGFDS
ISFTELSNAINRALGVEITPTLFFEQSTPAAIAEAIYGE-----------
>tr|B8I8K0|B8I8K0_CLOCE Beta-ketoacyl synthase OS=Clostridium cellulolyticum (strain ATCC 35319 / DSM 5812 / JCM 6584 / H10) GN=Ccel_0861 PE=4 SV=1
-----------------------------------------ENGSKVVYSQGKTSFNRDDDKTYTINPKSHEDYQELFKSLTQQGKSITNIIHLWD----
-----LSGKIGTNDTGLYSIMYIFRAVTALKLENRTRCLFTFRDNI----QVCQ--EAVSGFANSITSVNHRFSVQFDEYTLENV--TIPPVLAVELTSK
NVSNGMEISYENGERFIKQISRVEELGA--GDSNILKPQGVYIITGGVGGLGMIFARYLAKKYNARLALTGRSPFNKDTE---EKLSSL----KGLGGEA
IYCRGDIVSTEDTQRIVKEVKDAFG-GIDGIIHSAGLSGEKSVMEVDRNDFEKIMLAKTHGLINLDLTTKDEAD-FIALFSSISSIVGDFGGCSYATANS
FLDRYAYARSAQVKGITLSIDWPLWGGGGLELPEEMAAL-EYSGMKPINAETGLKAFEDALRS-------------GCIQLIVAGGD--N--RKVDRALK
---------------------VGRGKGAEAASVELQETENKPEGSQESMI----------------LEQAEEYLKGLLSNTINAERINAKLPLEKYGIDS
VMIMEINSLLEKDFDS-LPKTLLFEYSNLHDLAKYFVKN-----------
>tr|Q2XNF8|Q2XNF8_LYSLA Nonribosomal peptide synthetase-polyketide synthase hybrid OS=Lysobacter lactamgenus GN=cpbI PE=4 SV=1
DWFYVPMWRLRGAKPGADATLADALVMGDRGGIGERLSALRRAGQRVVVVRPGDAFVRLDQDEYALAPDDEGHYGELAAALQRDGLRIDRLVTLWSLDPL
A---AAADADAAAGSGSFSLMFAIKALMAHNEGAAIHAVTQDAYRVTAAESPASEQAAIVGLCKVAPQEYPTLRCQHIDFSRREPDFAASAAASLFAEVA
AGRADKFVAFRRAARWTQTYEQQKVAAED--AAPRFRRGGVYVITGALGKVAYALADHL-ASMAAKLVMVVRDDLPPRSVSPGDPVPKLRLLALECGAQL
LVCKADVTDEAQMLEVFEQAEVR-YSRIDGVIHCAGQVRESVLSDIDLAHCREQFLPKVKGAMVLQRVLKHRDVDFCVLMSSLSAVLGGLGFAAYAGANA
CLDAFAAARHAQGDERWLSIDWDGWKFPGEGEDA-------AYGV---SAVEGAQALAYALSADLP--------------QLVHST----------ADLK
TRMDKWV-EKLAQE-------------PA---------------------HMRLYVRGGGAATVAPSNTIEFQLLEIWQQLLGIQDIGVRDAFFEAGGDS
LLATIMVARINKAFGVNLPIRIVFEEETIERIALQIDELTKRP-------
>tr|A9ECY5|A9ECY5_9FLAO Keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase OS=Kordia algicida OT-1 GN=KAOT1_04255 PE=4 SV=1
--YYTHIWEASSVTKNAKDTSKSIVVFDTDEKLFNSYKKDT--KTPVILVQQGKAFQKVSDNQFTINPENKEDFNQLFTSLQEQGIGLDKICYGWSKDTF
KED--EKSLDNALKTGVYAFLYVCQAVMQLKNNISIAYFYHGAENDAQP--H---NAAINGFAKSLHLEQSSI--SCKTIEILEVEDSSKIAELVIAELQ
EDTVELAVRYEGEERFVRKLQNIANWRKNNTNKQGIKEKGVYLITGGAGGLGFIFAEYLAKECKARLVLTGR---SKLSEEKSAKIAILE----ELGAEV
LYVASDVSKLKDVKKVIAATKKKF-GAINGILHSAGVLRDSNIRNKTIEEMQAVFAPKIYGAYYLDTLTKDTELDFFVTFSSMAAVGGNMGQSDYSYANH
FMDTYVKRREALKGGKSLSLNWSIWANGGMKLDAQMEAFFNSLGIRPLKSEIGIGTFTRGLFAEETQVV-VVEGMRMEIAWGIRE---KEEEPQTATGNE
ASTNVATTDEASGEITGLVRQ---------------------------------------------------DLIQIVMDFLEEEDVAVDKILLDIGFDS
IGLASYANALNEKYGLDITPVLFFEYPSINEITKYLVKD-----------
>tr|A0A023BPR4|A0A023BPR4_9FLAO Uncharacterized protein OS=Aquimarina atlantica GN=ATO12_04990 PE=4 SV=1
--YYSHEWKKSLLEQEKVNESGPILLFSPDEKLQKVYKDRYKKNEDIILIEPGDKFKKLGSHKYKINPQNPADFKKLFEALNKDI--IKNICFAWPIGDE
LKDDEEGFIQKSFDNGIYSFLMLCQSLIEQKDNVQLLYLYLGQIGTSQP--H---HEAINGFAKTLQMEHPKL--YCKILEIQQSKKYDKILDIVLTELH
SDNSNMTIRYQEEERYVRKVKEFSLLQDQDDDSFGLKEKGVYIITGGAGGLGLIFAEYLAAQCKARLVLTGR---SKLSGERQTKLDRLS----EVGAEV
MYIPADVSIAKDVENLVKKAKSKF-GKINGIIHSAGVLRDSYVRSKTREEMEAVFAPKVYGTLYLDRITKDEDLDFFVTFSSLAAVGGNAGQCDYSFANH
FMDSFAEKRKLLKGGVTLSLNWSLWADGGMKLDEQTEIFFKNLGIKPLSIKTGLEAFEKGLHTRKAQFV-VLEGVKIERAWGIKE---KETPEAVATDSK
TSTEVQVDQQADKELFIVVRD---------------------------------------------------ALSKIVMEMLDPEDISYDKILLDLGFDS
IGLTTYANRINELYELDITPVLFFEYPSIKEIATFLSRE-----------
>tr|F8TUA6|F8TUA6_9GAMM Keto-hydroxyglutarate-aldolase/polyketide synthase OS=Lysobacter sp. ATCC 53042 PE=4 SV=1
--YYSHEWRAAELGEG--DDGTALWLLDSDEILYAALRAR---GVNAALAVPGEDYADLGGGRFRLNPREREHYARALAALAAQGRAPQRIVCHWAKFEA
PQD--DAALDAALAHAPYALLALAQALAESKGRVRLCWLHRGG-AALQP--H---NEAVDGFLRSLALEHPKF--DCKTVALDEAPA-ERVALRVLAELD
ARAQLPSARYRDGAREIRRLVRV------EAAALAARENPVYVITGGAGGLGLLFAEHFASQGGARLLLTGR---SALDPQREAELERLR----ELGAQV
IYAAADVSRADEAERVLALARDRY-GRIDGIVHAAGVLRDSFARNKSAQDLDAVFAPKIRGALHLDRFSAGDELDCFVLFSSLAALGGNTGQCDYAYANH
WLDSFAAQRDSLAGGRSLSVNWSLWADGGMKLDAQTELFFKNLGIKPLDAAVGVAALAKALSLGRAQVA-VLEGAKIEQAWGLNR---EIAVAPLAAPAV
VAAPAASNAGQGDALAAEVVK---------------------------------------------------TLSALVMDMLGADELDLDGILLDLGFDS
IGLTGFANAINERYALDINPVLFFEYPSIRAIAGALTSE-----------
>tr|A0A085WVX3|A0A085WVX3_9DELT Malonyl CoA-acyl carrier protein transacylase OS=Hyalangium minutum GN=DB31_0097 PE=4 SV=1
---------------------------AHSQGLRRQLRERSGE-APIIRVQPGEGFRCLSPEHYQITPAREEDYRQLWEALRERGLQPAALFHLWNHEAR
PLAETVSTELQEQLLGLQSLFLLARTLPGLR--LRERLPVIYAFQGEGEQPQH---SAVAGFARSVALENPKLRVRVVRFAPRQAEVP-ADWDALLRELQ
PPEQTEVRIGSAG-RQVRRFAPVAPPASGTSARPLLRPRGVYLLTGGAGGLGLVFARYLAREAQARVALLGRSPLDAA---RRASLSELEA----MGAEV
LYLSADVADPAALQTAVTRVRERFG-ALHGIIHAAGVIEDAMAVNKPLNSFQRVLTPKIQGTLNLDAATREVPLDFLVLFSSASAVFGSMGQTDYAAGNQ
FMDAFATLLR-ERGLRTLSLNWPLWREGGMRIQPEVEEMLRNTGLKVLETGRGLTAFSLAQALPGS-------------QLMLLEGD--P----------
---A--VIHK---RIELATQPVV---RPQRSAPPPPAAPEPAVA--ERAV--------APPTLETLQSHLEQDLSETCSALLKVSTSDAEADFSDYGVDS
LMIMRILDHLEERYTVSLDPSALTEHPSIRSLAKHL--------------
>tr|V6L2E7|V6L2E7_9ACTN Uncharacterized protein (Fragment) OS=Streptomycetaceae bacterium MP113-05 GN=N566_06530 PE=4 SV=1
---------------------------DRVQAIR-------AH-NAAVLVTPGSGFARLSAEHFTVSPDSLEDHKELRAALEGDGLAPSAIVHLWHLDGS
DP----------HKTGLLSVYALCQAW-AVG--RRTALPVVHAYHSRGESPPD---ASVGGLARGLRLEQPKLPLSTVRFAAPSADAA-AAAEAVLGETG
SPGDLEVRYTSAGVREVRGFAPVAPTPSGTP---LARAGGTYLLSGGTGGIARHVARHMARAAQPNIVLFGRSSEGEG---QRAFVAELAR----LGARA
AYLQADVTRLDDVERLVAEAENRFG-PVTGVIHTAGVVEDGLLINKKPDSVRRVLAPKFDGARNLDLATADRALDYLVLFSSTSAVLGSIGTTDYTAANA
YMDAFTDWLV-ARGERSVAVNWPLWSEGGMRINPAVEAQLETTGLVPLETAHGLAALEAGLAHDGP-------------QLAVFEGD--R----------
---T--KVER---MLAVIWPQRV---RADGYAPHRPVKTQHDGA--ESGV--------AD---VEMASELEAMIAETVTGLLPQTASLMSWTFMELGLSS
VDVVGLSRRLGEQLCIDLSPTVFFRCTHVPELSAHL--------------
>tr|A0A0P9R3Q7|A0A0P9R3Q7_9PSED Non-ribosomal peptide synthetase/polyketide synthetase (Fragment) OS=Pseudomonas syringae pv. helianthi GN=ALO68_04767 PE=4 SV=
DWFYQRQWLRVRRLGTQTELRGVVVCAHERMEA-AVLDSLQSVYRQVVEVQAGNGYQQLGPSRYELDPLDPLAFSRLIAALEHNGHTATELDWLHALPLS
VGGVVGEQSATAQWACLDTVSALLQAWGASEHKTALRLLSWQACPVNGTV-LRPELAALAGVTEVAPQEYP-IRCHWLDLPAARLDTQARQLAALLAD--
PMSLPRRMAIRDDYLWQPQLQASPLAEPAAV-SNLLPANGTFLVLGGTGGIGRTLCEHLLQSSQRRVVLLSRRSEIA--Q----S-------LHAHASRI
DSVQADIADLARWPGVLEQLRE-RYGQFDGVIHAAGTGAGSLIRQRDARVLSEAMASKTRGMLAVEALIEQMKPGFVLYCSSMSALFGGAGHLDYAAASA
VLDGFTYYRPNNGCVR-LGINWDIWRDIGMAAAAGICDEAHQRHLAGMSAQEGCRIFDAALTAQL------------P-QLLISTTE--L----------
------NTARQFYP------ARH-GGSDSTVIEAA---------P--------------AFAAET---GLRERLHGCLCKWLGVSALEENDSFYELGADS
LTLLDLIDELQAATGVVFQLSQFSHRVSLLEVLTLVQQA-----------
>tr|I1D2G5|I1D2G5_9PSEU Amino acid adenylation enzyme/thioester reductase family protein OS=Saccharomonospora glauca K62 GN=SacglDRAFT_02240 PE=4 SV=1
DWFSTTTWTRAPRPSVPDTSW--LLVGPDTIA----GELVGARGDRVTEVRWGGSFTDLGADGYLVAPENPEDWERLVTALR-------------ALPAH
ITGTLDGDADSGPFRDFHAVLFLLRALARNRITEVSVVAVSGLAVADEPA-LRPERGMLSSLLRVAEQELAELRFRYLDVGPVEPGERRERLRDHLV---
LAGEETCVAYRGLDRWLPGYAGVALPETG---TSLLRSDGCYLVVGGLGRLGSAIARQL---AGCRIGVVRRSALPP--A----EKWSRIRELREAGCEV
VTASADVADEEAFREAVARLEE-RLGHFDGVFHVAGVVSDDRLVDVTPDHVRPHLAAKVHGLAVLDRVLSDRKRDFVLVSSSLSSVLGGAGLAAYAAAAR
YAELFALRRSTGDTPW-LALTWDAWRDTGRLGL---------------DDAEAAEVVRRVLTGDP------------PAHLVISTAD--L----------
------SARIAETA------SERDGEKPGPEVPET----------VYP--------RPDLATEYLAPNDVERRICALWQGLLGIDRVGVRDNFFELGGHS
LLAVRLVSALQAEFPDATSLATVLKATTVELLAGKLGAA-----------
>tr|A0A0P9PKV4|A0A0P9PKV4_9PSED Mixed non-ribosomal peptide synthetase/polyketide synthetase OS=Pseudomonas congelans GN=ALO92_03298 PE=4 SV=1
DWFYQRQWQRLHRLRTQPEGREVVVCSHERLEA-DTLGSLQGVYRHVIEVQAGNGYQQLGPNRYELDPLDPVAFGRLIATLDQNGQTAAELDWLHALPLS
VGGAVDEQSAAAQWACLDTLSALLQAWGQNAQKSALRLLSWQACPVNGPV-MRPELAALAGITEVAPQEYP-IRCHWLDLPTAQLSTQARHLAALLAD--
PASLPRRMAMRDGYLWQPQLQASPLAAPTAD-SNLLPANGTLLVLGGTGGIGRTLCEHLLQSGQWRVVLLSRGGECP--K----E-------LHAYASRI
DSIAADIADLARWPTVLEHLRE-RYGHFDGVIHAAGTGAGSLIRQRDAQMLSEAMASKTRGMLAVEALIEQMTPGFVLYCSSMSALFGGAGHLDYAAASA
VLDGFTHYRPHNGCVR-LGINWDIWRDVGMAAASGIGDDAHQRHLAGMSAQEGCRVFDAAMTAQL------------P-QLLISTTD--P----------
------ETARQFYP------VRH-SA-GSTLADTA---------P--------------ALTADTEADRLPEHLHDCLCKWLGVSALQPDASLYELGADS
LTLLDLIDELQAATGVVFQLSQFSHKVSLAEVLALVQA------------
>tr|A0A0M8SJM8|A0A0M8SJM8_9ACTN Peptide synthetase OS=Streptomyces sp. WM6378 GN=ADK54_27970 PE=4 SV=1
AWLHQPHWVRRRRAVPEPGTPGLVVVAAGPLAA-EALRGLNTGGGRVVRVEAAGAFARLADDRFGVDPTDPVSLRRLLDALP---AGGERIDWLHALPLA
VDGEVGADTERARRACLDAPAALLQALAGFPGADRVRWLSHQAQPVEMDV-RRPELGLLAGACEVGSQEYG-VDCHWLDLPNGDLAEWAALLVAVLAD--
RVALPRRLALRQGYWWQQALLGVTATETS---PAPLAAHGVHLVLGGTGGIGAGIAAWLLSQSDARVVLLARRPRLP--A----D-------LAPWADRV
ELIAADLAEEDTR-TILARIDR-LGHRIDGVVHAAGVPGGGLIGGRDGAAMRAATAAKLGGALLVERLIARHRPRFAAYCSSMSALFGGVGQFDYAAANG
LLDGFARHRGDESTVR-IGIGWDIWNEVGMARGALATDRRHQAHLAGLTLKEGQRLFARALRLQL------------P-QLLISTTA--V----------
------EEARAFYE------APA-DEAPGA---------------T-------------------A--SIAELLADWLREWLGLDDLDPEVSLYDYGADS
LTMLDLIAKVKRHCGIDLELSQLTHEASLSEILGLLD-------------
>tr|F3NHF8|F3NHF8_9ACTN Putative NRPS OS=Streptomyces griseoaurantiacus M045 GN=SGM_2572 PE=4 SV=1
RWLHQPHWVRLRRAGTATDPA--VLVTDDPAGP-ARARELRALRPRVVLVTAGETFARLDEDSYRVDPADPEALGQLLDVLD----GLGTVDWLHALPLG
VDGPVDEERRRARRACLDAPAALVRAAAGR-TGIVPRWLSYRARPVDGPV-DRPELALLTGVTEVAPQEGA-APGLWVDLPAADLAAVPPLASLLA-S--
GEELPTHLALRRGYWWRRDTAPVTAPATAAD-TVPAGPDTVHLVLGGTGGIGATLAGWLLERTAGRVLLLSRHPALP--E----P-------LTARADRI
DLVTADLTAATPD-ALAALVAE-RTGRLDTVVHAAGEGTGGLLARRDPATAHAGSLAKLNGALLVERLIERFRPRTALYCSSMAGTLGGVGQYDYAAAAG
VLDAFAHHEPEGDTLR-LSLAWDVWREVGMALRVPSADARHRAHLAGLTVPEGRRTLERALSAGL------------P-HVLVSTTE--P----------
------QASRAFYA------GPA-PVPAAT-APAT---------PAATVP----ADAATSASAAVPGGEAAALVGGWLREWLGLDTLAPDTPLYDLGADS
LTLLELIDRIKRHFDVELDLAELSPDVTLTEVLTLLDRS-----------
>tr|S3ZEQ5|S3ZEQ5_9ACTN Putative Dimodular nonribosomal peptide synthase OS=Streptomyces aurantiacus JA 4570 GN=STRAU_5766 PE=4 SV=1
DWLHQPHWVRLSRARTSPHTP-GVAMTATPLSP-EALRVLEARYERVVRVGAAAAFARLAEDVYEVDPADPDSLRQLLGALA---AGRAGIDWLHALPLA
VAGPVGERSDHARWACLDTPAALMRAADVLPPSVRLRWLSYGAQPVEGEV-RRPELGLLAGAAEVVPQECA-VDGHWLDLPTGEPVDWAAALVGLLAA--
SAALPRRLALRQGFWWRQALLPVPAPEVMEP-GGVADEPGTHVILGGTGGIGCALAAWLLAQSDCRVVLLARRPRLP--A----D-------LAQWTDRV
ELIEADLSAEPPE-EILSRIER-HTGRVDGVVHAAGEAGGALITRRDGAAMRRAMAAKVRGALLTELLIERFRPDFAAYCSSMSALFGGIGQFDYAAAGG
LLDAFARHRAGETTAR-IGIGWDIWSEVGMARDALRSDARHQAHLAGLAEKEGQRLFARALRLQL------------P-HLLVSTTD--I----------
------ERARAFYT------APA-GPAQGPSGTSQ----------DE----------HG-----ATPAAVASRLTGVLCGLLGLDELDPEASLYDHGADS
LTLLDLIATVEEHFGVALDLSRLSHQVSVREVVAHIRDA-----------
>tr|L8EV57|L8EV57_STRRM Amino acid adenylation enzyme/thioester reductase OS=Streptomyces rimosus subsp. rimosus ATCC 10970 GN=SRIM_11471 PE=4 SV=1
DWLHQPHWVRLSRAVPAPRTPGGVVMTAEPLPP-ESLRLFEAGWSRVVRVGAADAYARPADDVYEVDPADPASLRQLLDALG---PGETVIDWLHALPLA
VDGPVDEDATRARWACLDTPAALLQAVAGTPLAEKVRWLSYGAQPVEGPV-LRPELGLLAGVCEVAPQECA-VDGRWLDLPSRELADCAHQLAALPGN--
SGTLPRRLALRQGYWWQQALLPVPTPAT-AP-SVLPDEAGTYLILGGTGGIGSSIAAWLLERSDCRVILLSRQPRVP--A----E-------LTAWADRV
ELVEADLAETPTE-TVLTRIEA-VAHRIDGVVHAAGTAAGGLVTRRDAPAMRQATAAKLHGALLAERLIERHRPAFAAYCSSMAAQFGGIGQFDYAAANG
LLDGFARHRAGEATLR-IGIDWDIWSEVGMARDALRTDARHQAHLAGLAVKEGRQLFARALELQL------------P-QLLVSTTP--I----------
------EEARAFYA------APA-DASVSPVTPGT----------A------------T-----ASAASASAELTDWLGRWLGLDELDPDASLYDQGADS
LTMLDLIGKVAEHFGVDLELSQLSHQVSLNEVLVKAGAE-----------
>tr|A0A0P7LNS9|A0A0P7LNS9_9PSED Thioester reductase OS=Pseudomonas sp. In5 GN=AL066_08290 PE=4 SV=1
DWFYQRQWVRVRRLNTVVERRETVICSNETLDT-TLLESLNTVYQRVIHLRAGNGFKRLGTDRFELDPLDAQALSRLLDELA--EPALGELDWLHALPLS
VTGAVNEQSAAAQWAGLDTVSALMQAWGQASRATTLRLMSWQACPVDGEV-IRPELAALAGITEVVPQEYP-VRCHWLDWPTFRMGA--QELATLLAD--
PASLPRRMAIRDGYLWQPRLIASPLPASVPM-ANRLPMDGMFLVLGGTGGIGRTLAEHLLQAPQRRIVVLSRRGELP--A----A-------LAAYGSRI
DCVQADIADLANWPAVLEQLAR-CYGRFAGVIHAAGVGAGSLIRQRDARQLGEAMAAKTRGMLAVEALISTMNPGFVLYCSSMSALFGGAGHMDYAAASA
LLDGFAHYRPSSDCVR-LGINWDIWRDIGMATTSGTGDAAHQEHLTGMSAEEGCRVFDLAMTTQL------------P-QLLISTTG--I----------
------DTARRFYP------VRH-GAVIAPV--------------------------------NVPELDLHSHLHESLCKWLGVTRLDDDDSLYELGADS
LTLLDLIDELQAATGVVFQLSQFSHKVSLQEILALVDAA-----------
>tr|A0A0D0J6A9|A0A0D0J6A9_PSEFL Thioester reductase OS=Pseudomonas fluorescens GN=RU10_21240 PE=4 SV=1
DWFHQRQWVRTRRLSATAGSREVILCSHDAPES-TLLASLNAVYRRVIQVRTGNGFKRLSTDRFELDPLDAEALSRLLAEVA--EPALGELDWLHALPLA
VAGAVNEQSDLAQWACLDTVSALMQAWGQTPRTTRLRLMSWQACPVDGEV-QRPELAALAGVTEVVPQEYP-VRCHWLDWPSSRLGAHAGEFAALLAD--
PVSLPRRMAVRDGYLWQPRLMPQPLTGPATT-SGLLPEDGTFLVLGGSGGIGRTLCEHLLQAPARRVVLLSREGQLP--A----S-------LAAYALRI
DCIKADIADLPRWPQVLDQLAV-RYGRVSGVIHAAGVGAGSLIRHRDARQMAQAMAAKTRGMLAVEALIEHLTPDFVLYCSSMSALFGGAGHLDYAAASG
VLDGFTHYRPNDACLR-LEINWDIWRDIGMATTSNSADTAHLEHLTGLSAEEGCRVFDLAMATQL------------P-QLLISTTG--I----------
------DTARRFYP------VRH-GAVAAVV--------------------------------EAPKVDLSTRLRECLCKWLGVAELEDDDSLYDLGADS
LTLLDLIDELQAATGEVFQLSQFSHKVSLSEVLGLVSTA-----------
>tr|A0A0G8ANC3|A0A0G8ANC3_PSEAJ Thioester reductase OS=Pseudomonas amygdali pv. tabaci str. ATCC 11528 GN=AAY86_06730 PE=4 SV=1
DWFYQRQWQRVRRLGTQPERRDRVVCSHERVDA-ALLGSLQGVYRHVIEVQAGNGYQQLGPNRYELDPLDPLAFSRLIAELDQSGQAATELDWLHALPLS
VGGVVNEQSAAAQWACLDTVSAFLQAWGQRAQKTALRLLSWQACPVNGQV-MRPELAALAGITEVAPQEYP-IRCHWLDLPTAQWGTQARQLATLLAE--
PTSLPRRMAIRDGYLWQPQLQPSSLALPTVV-SNLLPVNGTFLVLGGTGGIGRTLCEHLLRSSQRRVVLLSRRGECP--Q----T-------LGDYAARI
DSVQADIADLARWPQVLEQLRE-RYGRFDGVIHAAGTGAGSLIRQRDAHLLSEAMASKTRGMLAVEALIEQMTPGFVLYCSSMSALFGGAGHLDYAAASA
VLDGFAHYRPNNGCVR-LGINWDIWRETGMAAASGIGDEAHQRHLAGMSSQEGCQVFDAAMTAQL------------P-QLLISTTD--L----------
------NTARQFYP------ARH-SGAGLTLVDTA---------P--------------AVAAET---GLPERLHGCLCKWLGVSALDPDDSLYELGADS
LTLLDLIDELQAATGVVFQLSQFSHKVSLREVLALVQSA-----------
>tr|A0A0N0ERZ5|A0A0N0ERZ5_9PSED Non-ribosomal peptide synthetase/polyketide synthetase OS=Pseudomonas coronafaciens pv. oryzae GN=AC511_0541 PE=4 SV=1
DWFHQRQWQRVRRLNQNMLRRDMVVCSQERLDS-TVLGCLSEVYRQVIEVCAGNGYQRLGPDRYELDPLDSSAFSRLIAELTQRA-PLTELDWLHALPLS
VSGAVNEQSAAGQWACLDTVCALLQAWGQTPRTMVLRLLSWQACPVNGDV-QRPELAALAGITEVAPQEYP-IRCHWLDLPEPRLSLYARPLAALLAD--
PALLPRRMAIRDDYLWQTRLQASPLVAPATV-SNLLPVDGTFLLLGGTGGIGRTLGEHLLQSSQRRLVVLSRSGNCP--D----N-------LLGYRSRI
DLIAADIADLARWPAVLDSLRQ-RYGRFDGVIHAAGTGAGSLIRQRDAQTLAASMASKTLGMLAVEELVKQMTPGFVLYCSSMSALFGGAGHVDYAAASA
VLDGFAHYRADDTCVR-LSINWDIWRAIGMAAAEGVGDAAHQQHLAGLTAQEGGQVFDAALGAQL------------P-QLLISTTR--L----------
------ETARQFYP------LRH-GAASSPT-D---------------------------IKLAGQSTDLRERLQDCLCKWLGVPSLDEEASLYELGADS
LTLLDLIDELQAATGEVLQLSQFSPTVSLREVLMLVQSS-----------
>tr|A0A0N8SNE7|A0A0N8SNE7_PSESI Non-ribosomal peptide synthetase/polyketide synthetase OS=Pseudomonas syringae pv. ribicola GN=ALO47_02540 PE=4 SV=1
DWFYQRQWQRVRRLSSRPQPRELVVCSHEALDD-TLRSCLKNVYRRVVEVTAGNGFQRLATDRFVLDPLDTPALTRLLDILAGDQSAPLELDWLHALPLS
VTGRVNEQSAAAQWACLDTVSALLQGWGQTSRTPALRLVSWQACPVYGEV-KRPELAALAGITEVVPQEYP-VRCHWLDLNSAQLAARPEALAALLAD--
PVVAPRRMAIRDHYLWQPHLQASPVMASTVD-PCLLPQDGVFLVIGGSGGIGRTLCEHLLRNGQRRVVLLSRHGECP--D----A-------LQAYRSRI
DPVQADIANRTVWPQVLEQLER-RYGHFDGVIHAAGVGAGSLIRHRDARTLSEAMAAKTLGMLAVEELIQQMTPKFVLYCSSMAALFGGAGHLDYAAASG
TLDGFTHYHPNSDCVR-LGINWDIWRDIGMATGAGAGDAVHQRHLAGMSAQEGCQVFDVALSAQL------------P-QLLISTTS--I----------
------EKARQFYP------VRH-GAGSVAAQPVA---------QVS----------ASTAPGKEEQADLRTRLHDCLCKWLGVTELDEDNSLYELGADS
LTLLDLIDELQAATGVVVELSRFSHKVSLREVLALVQTD-----------
>tr|M3C7L2|M3C7L2_STRMB Amino acid adenylation protein OS=Streptomyces mobaraensis NBRC 13819 = DSM 40847 GN=H340_13706 PE=4 SV=1
EWLRQPHWVRRHHAGTDPRVAGMVVLTDGPLPE-GALRPFEAAFERVAHVRAAASFARVGADRYEADPADPGSLRQLFDALG---AGADTVDWLHALPLA
VEGPVGEEAERARWACLDTPAALLRAAADLPAGTRLRWLSYGAHPVEGPV-TRPELGLLAGASEVVPQECG-VDGRWLDLPGRDPADWAALPALLAEP--
AAELPRRLALRQGYWWRQALLPVPAPAPVAA-PARPVGPGTYLVLGGTGGIGRSVAARLLEHAGCRVVLLARHAELP--E----E-------LAPWADRV
DLLEADLATEAPE-AVLDR----LATRVDGVVHAAGVAAGGLLLRRDAAAARAASAAKLRGALLVERLIERDRPAFAVYCSSMAAQLGGVGQFDYAAANG
LLDGFARYQGDGSTLR-IGVGWDVWSETGMALDALHADARHQAHLAGLTVKEGQRLFADALRLRL------------P-QLLVSTTD--P----------
------EEARVFYA------PPP-GAGRPA---------------TA----------EA-----RPAPAAAERLAEWLRRSLGVDELDPEASLYDHGADS
LTLLDLIGTVEEEYGVELELSRLSHRVSLAEVLAHLAEA-----------
>tr|A0A0K9XBZ3|A0A0K9XBZ3_9ACTN Peptide synthetase OS=Streptomyces caatingaensis GN=AC230_19390 PE=4 SV=1
AWLHQPHWVRWRHASGTARGAGTVVLTDGPLPS-GALRPFEAVYERVVHVRAAAAFARAGADRYEADPAEPASLRRVLDALT---AGATGVDWLHALPLA
VEGEPDEETERARWACLDTPAALLRAAAGLPAGTRLRWLSYGAQPVEGPV-VRPELGLLAGASEVVPQECG-VEGRWVDLPGRDPAGWAPLAALLAAA--
GGEPPRRLALRQGYWWRQALLPVPAPAP--A-PEHPAGPGTYVVLGGTGGIGRSVAARLLDGPDRRVVLVARRAELP--E----E-------LEPWAGRV
DLLEADLATAAPE-EVLARLAR-VAPRVDGVVHAAGVAAGGLLARRDAAAARHASAAKVRGALLVERLIERHRPAFAVYCSSMSAQFGGVGQFDYAAANG
LLDGFARYGGGGTTLR-VGIDWDVWNETGMALGAPEADARHRAHLAGLTVKEGQRLFADALRLGL------------P-QLLVCTTE--M----------
------EQARVFYA------PRP-GTAPVA---------------AP----------AS-----APAVPAAGRLADWLCRSLGVDALDPEASLYDLGADS
LTLLDLISTVQEEYGVELELSRLSHRVSLSEVLEHLAAA-----------
>tr|H2JY53|H2JY53_STRHJ NRPS-PKS protein OS=Streptomyces hygroscopicus subsp. jinggangensis (strain 5008) GN=SHJG_1133 PE=4 SV=1
RWLHQPLWVRLRRTRAHSGAAARVVVVPPGTGS-GAWRELERHYARVVLVRAGDTFVRRDGTAYEADPADPAQLAALLAEVT---ADGAGVDWLHALPLA
VRGEVGRRSETARWACLDTVAALCRALADVPDARRPRLLSYGAQPVTGEV-ARPEAGLLTAAVRVPRQELG-LSLRWADLPGPEPADWAWCLPDLRDG--
AARSEPELALRGGYWWRRTVQAVPVPVAVAS-RPRPGRTGTHLVLGGTGGIGSTIAADLLRRAGNRVVLVGRRPGLP--A----V-------LAPWADRI
TRVRADLAEEAPE-PVADRLAPHL-DGLVGIVHAVGIAAGGLLVRRDRAKARPRTAAKLGAALLTERLIAAYRPDHVVYCSSMSARFGGVGLFDYAAANG
LLDAFAHYAPGDRTTR-VSIGWDAWREAGMAWDVSAPDARHKHHLAALTPEEGAAVFGQALELGL------------P-HLLVNTTP--L----------
------SEAGVFYG------PGA-AAPRRRTTPES---------PAPEQANPPAPAPVRTPPTAPVPADPLRDLTAATAHLLGLPGVDPDSSLYDLGADS
LTLLDLLDEVNRRFGADLDLSRLSHRVTLTEIAGHLRTG-----------
>tr|A0A0B5DST0|A0A0B5DST0_9ACTN Peptide synthetase OS=Streptomyces nodosus GN=SNOD_33510 PE=4 SV=1
QWLHQPLWARLRRARTGGPARIAHSADSGDSGD-EAWRFLERHYARVVTVRAGAVFTRIDEDRYQADPADPAHLSALLTRVT---GATPAVDWLHALPLA
LHGEPSTDAETGQWACLDTVAALTLAVAALPEGQRPNLLSHQAQPVTGDV-RTPEAGLLAAALEVPRQELG-VSARWADLPGPRPADWAAHLPDVLLD--
TALTMTATALRDGYWWHRTLQSVPVS--IPE-SAPPSIPGTHLVLGGTGGIGTTLAACLLRQPGNRVVLVARGTDTP--D----A-------LAAFPDRV
TLVSADLATEEPE-TIAARLAPHL-AGLTGIVHAAGTAAGGLLARREPVTARRATAAKLRGALLVELLLAEHDPDYALFCSSMAARFGGVGQFDYAAANA
FLDAHAHHAPSTRTVR-MSIGWDAWREVGMAQHALGTDSRHQAHLTALTPEEGATLFEQALDLRL------------P-HLMVNTTD--L----------
------AAASLFYE------PAP-RPRTPA---------------A------------D------D--DPTTALTAALCGLLGVDTIDPQAALYDLGADS
LTLLELLDEVKRLFGTDLDLSRLSHRVSLAEILGHLG-------------
>tr|A0A0M8VUG6|A0A0M8VUG6_9ACTN Peptide synthetase OS=Streptomyces sp. AS58 GN=ADL00_10120 PE=4 SV=1
QWLHQTQWTRLRRARTSTGEGRRVVAAAPDTAL-PSWGFLTRHYARVVTVRAGQTFRSLGDDAYEADLTDSGHLTALLDVLA---VAASGIDWLHTLPLA
LRGDIDESVDTAHWACLDTVAALARTLAGVPQAQRPRLLSHGAQPVTGAV-RTPAAGLLGAAPEVTRQELD-VTLRWADLPSPDPADFAAHLPDLLLD--
DGLADRATALRDGYWWHPAVQPVTAPAPPPA-ADPSAALGTHLVLGGTGGIGSTLAARLLEHPANRVVLVARGTDVP--D----A-------LRTHRDRV
ALVAADLAVDDLA-SVAKRLAPHLTEGLAGIVHAVGTAAGGLLAHRDTAAARRVTAAKLRGAVLVERLVAEHRPDYAAYCSSMAASYGGVGQFDYAAGNA
FLDACAHYAPHQSTAR-LSIGWDAWREVGMAQHALSADARHQDHLEALTPQDGSSVFARALHLRL------------P-HLLVSTTS--L----------
------DQARYFYE------PAR--PHGPA---------------AD----------VG-----AVALDATAELTGVLLDLLGTDSLDPDAALYDLGADS
LTLLELLDEVKRRYGSDVDLSRLSHRVSLAEIVGHLG-------------
>tr|D7C4Q8|D7C4Q8_STRBB Amino acid adenylation domain protein OS=Streptomyces bingchenggensis (strain BCW-1) GN=SBI_02988 PE=4 SV=1
QWLYQTDWVRMRRATRVKSVR--IVVADATSPP-AHWKALDGHGIRVVHVTAGQAYARLAQNRYEVDPADPDSLTRLLEAVT-AAATGGGVEWLHALPLG
VAGTVGEQSDRARHACLDAPSALCQALARLPQALRPRWLSHRAQPVTGPV-QRPELGLLAGALEIPRQELG-LETRWLDLPSGLASDWAELLSLVLAP--
ADTAPRRLALRQGYWWRAVQQPVRPPAQQAR-TILMEGSGTHLVLGGTGGVGSTIATRLLEQSDARVVLLARRPQLP--P----A-------LARWSDRI
TVVEADLAQEPLD-NVLARLAP-YLSRLDSIVHAVGTAAGGLLVRRDGDAMRHTTRAKLHGALLMERLIAAHRPGYAVYCSSMAAVLGGVGQFDYAAANG
VLDAFAHHGSDGATVR-IGIGWDVWRDVGMARTALTTDARHQAHLAGLSSAEALRVFSDALQLQL------------P-HLMVSTTP--L----------
------EETRYFYE------PDR-HELTST---------------SP-----------A-----MSTAVPHGELAEAVCQLLGVDTLDPDTCLYDLGADS
LTLLDLLSEVKRQYGVDIDLSRLSHQVTLNEVLTHLNGG-----------
>tr|G7M3G4|G7M3G4_9CLOT Long-chain-fatty-acid--(Acyl-carrier-protein) ligase., 6-deoxyerythronolide-B synthase OS=Clostridium sp. DL-VIII GN=CDLVIII_3725 PE=4 SV=1
-WFYNWNWKPEPHKYADSEIKGNIVIFSDNSEIEDEFEEIFKTNKYVVKV--G-TEYRFDYSKFIINPIAEEDYVKVFNIIQG---PVGAVIHLWNLNKE
SFKLEFAFDDKVMHEDIYSVLYIGKALSKL--NIEKTKLLLVTNNGNENKIPHQASAIT--LAQALDQENAFIDSYCIDVDKKEYESNREIAQILSDEIK
HDLSKGIVAIRGGVRFIRELSAIKFNQTS---KIKFNDGETYLITGGASAVGSEIAKVIAKKAKINLILTGREELPLIEKW-EEELANNTRYLKELGANV
IYEAVDVTKIGDMKALVERIADEYGA-IYGVIHAAGTFDSKTLLDKNIKVINKIIEPKLKGGIITDLVTRKEPLKFFVMSVSCSEKLWSAGVGDYAAANA
FLSAYSYYRA-ADNGKTIALNYSLWAGTGMGSDNGALLALKAQGLNPLPAKKAAEAFIRALSVESQVIHI-ID--KIEISDV-----EKSST-IKMPQVN
SRKLKNIKEIVYKVIAKQ------------------LKV-------------------------------------------EEDNFDVGKNFLELGLDS
LGAVKVMEMLGTSIGMELYPTLIFEYQTPQALAEYIEM------------
>tr|J3AWZ5|J3AWZ5_9BACL Beta-ketoacyl synthase family protein,phosphopantetheine-containing protein OS=Brevibacillus sp. CF112 GN=PMI08_04780 PE=4 SV=1
------------------------------------LVELQAREADVIEVAFGAAFEKGGDRQYKI--GSANDFPRLLQELAHRD--IRHIVHCMGMTEE
K-LACADDFHEWENRSVYSFCQLVCELLSYHQEINLYLLGDQAFSVTRREALNPQHAVLFGLAKVVAQEYPQLKCRCIDLDSA------TAPSTLWAEWE
AGEEDFQVAYRENVRYVERLEAQTLQAAEPQ-AVSIRENGVYLVTGGLGDIGLQVAHYLGNKQPVHLCLLARSAFPAREAGQIGQIRSI----EDSGSSV
EVHTVDVADERRLADVLQTIRQQYG-AIHGVFHCAGVAGEGLLINKGRAKIAQVLAPKVVGTWLLDRYTEQDRLDFFVLFSSVTSLLGGLGQADYTAANA
YLDAFSDYRQ-AKGRQSVTINWPAWNDTGMTARYRIQKEAS--PFCGMHPDKAIGILDAVLRRKLARVIV---------GE-------------------
------LNEAHFQAISPEIRSMFA--RPVAWEPEDATPL-------APMLTGRTD---------HTYSAVETRLAAVWQKVLGIPEANVYQSFQEQAETP
FSRPVSSKKSSSSTPRCSPILRLRKWRNIWKTSRVPTRR-----------
>tr|A0A0E4H817|A0A0E4H817_9BACL Beta-ketoacyl synthase family protein,phosphopantetheine-containing protein OS=Paenibacillus riograndensis SBR5 GN=PRIO_1742 PE
------------------------------------LRVLRKQEIELIEVTPGARYHQLAANRYSI--GSGEEYSLLLKELSNRG--IKHVIHCLSLADE
K-IAGIEDLHAAENRGVYNLHHLVTALLQYHQELNLFFVADHTFLVNRHEPLNPHHAVLFGMAKVIPQEYPQFKCRCIDIDSA------TAPATVWKEIC
SGKGDFQVAYRDNTRYLEHFGERRLEAAEAG-GVSLKENGVYVVTGGLGGIGLAVAQYLSGKQRVHLCLLNRRTLPPGP-SQSQRIRQI----EANGSDV
DLYSVDISAPNELQGVLQAIRTKYG-QINGLFHCAGIAGEGLLINKGKPEIKRVLDAKVTGTWLLDQYTAQDHLDYFVLFSSVTSLLGGMGQADYTAANA
YLDGFSDYRQ-ANNRRSVTINWPAWKEVGMTLKYDIQEGRS--PFLGLTEEQGISILDAVLQRKLSRIIA---------GE-------------------
------INERYFQAVPPQMISRGT--GPQEKVIA-DEPI-------LPILKGRYD---------HSYNSYEISLAAMWQKVLGVAEVNVHLPFQETGGNS
ILATSLVKEIDGVYPGCVNIATLFAYPSIAKMAEYLKQK-----------
>tr|A0A089M5F9|A0A089M5F9_9BACL Beta-ketoacyl synthase OS=Paenibacillus graminis GN=PGRAT_08135 PE=4 SV=1
------------------------------------LSELRKQEIELIEVTPGTHYHQLAANRYSI--GSGEEYSLLLKELSNRR--VRNIIHCLSLADE
K-IAGIEDLHAAENRGVYNLYHLVTELLQYHQELNLFFVADHTFRVNRHEPLSPHHAVMFGLAKVIPQEYPQFKCRCIDIDNA------TASAAVWEEIC
SGSADFQVAYRDNTRYIEHLEERLLGAAEAG-GVSLQENGVYVVTGGLGGIGLAVAHYLSGKQRVHVCLLNRGTSPPGP-SQIERIRQI----EANGSEV
DLYTADISEPDELQGVLQAIRTKYG-QIHGLFHCAGIAGEGLLINKEKPEIKRVLDAKVTGTWLLDQYTAQDNLDYFVLFSSVTSLLGGMGQADYTAANA
YLDVFSDYRQ-ANNRRSVTINWPAWKEVGMTLKYDIQEGLS--PFLGLTEEQGISILDAVLQRKLSRIIV---------GQ-------------------
------INERHFRVVPPQIISRGT--GPEARATASVPPI-------MPVLKGRNN---------HSYNSYETSLAAMWQRVLGVAEVNVYLPFQETGGNS
ILATSLVKEMDDVYPGCVNIATLFAYPSIAQMAEYLEQK-----------
>tr|A0A0H0SPI9|A0A0H0SPI9_9BACL Beta-ketoacyl synthase OS=Brevibacillus formosus GN=AA984_00040 PE=4 SV=1
------------------------------------LQEIRERKIDLIEVSSGPAFQKFSDHHYQI--GSKEDYPVLLKELMNRN--IRNIIHCMSVVDE
E-IECAEDLHARENKGVYSFYHLVCEMLSYNQQINLYVIGDHTFSLTKHESLKPHHAVLFGMAKVIPQEYSQLKCRCIDIDSD------TSPATVWKEIC
ADKEDFQVAYRHNVRYIEHLEEQMLGNSELQ-DIAIKENGVYLVTGGLGDIGLKVAQYLSTKKSVHLCLLGRNVLPPREASQIDMIRRI----EKNGSSV
EVYAVDIANESKLADVLETIRHQHG-AIHGLFHCAGVAGEGLLINKEHAQMKQVLDPKVIGTWLLDRYTERDHLDFFVLFSSVTSLLGGIGQADYTAANA
YLDVFSEYRQ-AKGQRSVTINWPAWNDTGMAAKYRIKKEAA--PFHGIHPDQAIDILDSILARKVSRVIV---------GE-------------------
------MNEAHFRIISPGIRRMVT--QPVAFEAIEEQQI-------VPILKGRNN---------HRYSDIETQLASIWQKVLGIPEANVYQSFQEAGGNS
ILATSLVKEIDQLYPGRINIATLFAYPSIAKMAEYLENK-----------
>tr|T1SF54|T1SF54_MYXFU Hybrid polyketide synthase/nonribosomal peptide synthetase OS=Myxococcus fulvus GN=mxnI PE=4 SV=1
--LYRSVFVRSELASGREKGLGPVLVLARDARFVERLREGPGERPQLVWARPADRFAERDGLAFDFDSRRPEELARLLDTLRTRGLAPSVVIHGFSYGRD
E-------LQAQLQDGALSVFHLSKALLRERNERPVSFLYVY----PATELPQPLSAALTGLARSVRLETEGLKLKVVQVESPEEM-----ADAAASELA
PDADGDSFVYVETLEPLCFDEA---GA----AQPRFKDGGAYLITGGAGALGLHLARHLTQRVRARVALCGRA---RLSEAQQREVDGLR----ALGAEV
DYFVTDVTDFSDVEMLADTLRARYG-GVQGIIHAAGQRQDQLLARKDAAQFAAVIAPKVFGTINLDRAFAAERLDFFVVFSSALTGNVGQ--TDYAFANA
FLKGFTAFRE-GL-VLNHAISWPYWKEGGM----KVDFIRSFFGTQPLETAAGLRAFEEIVGRGIPELVLSPGAVPARFLKDS-----------------
---------------AVATQAMV--------APVRHEPAP-------------------------AQRAIREEVRRIAAGLLQMTALDEHKDLAEYGYDS
ISFTELATALNAAFGAELTPAVFFELTPLNALVAYLEAR-----------
>tr|D7RK25|D7RK25_CORCK CorI OS=Corallococcus coralloides GN=corI PE=4 SV=1
--LYRTVLERADVTP--RGVSGPVLVVSRDAGFVEQLRSGAGARPSLVWARPAERFQARDDWTFDFDARRPEEPGRVLEALRARKLSPAAVVHAFTYDAD
A-------LKAQLQDGALRVFHLCQALLRDGLERPLPFLSVF----PASEAPHPLSAALKGFARSVRLESDLLNLTVVQAERPESM-----ADAAFAELS
AGTTAEPFVHVEVLAPMSSGEA---EP----ARPVLPNGGTCLITGGAGALGLHLARHLARRPGVRVALCGRS---ALTEATRARLESLR----AQGADV
EYFVADVTEPGDVELLVDTLRARYG-GLQGVIHAAGERRDARLVKKTAAEFEAVLAPKVTGTLLLDRALAAEKLEFFAVFSSARTGNVGQ--TDYAFANA
FLEDFRAFRD-GL-CQSHAIAWPYWREGGM----KVDFIRSFFGTEPLDTATGLDAFDAVLGRRLPELVLGRGA-PARFLKAA-----------------
---------------AEPS------------LPERSEPVPAVAP-----------------PRPAELPGLLDEVRHIVAGLLQLASLDPRKDLAEYGYDS
ISFTELATALNTAFGSELTPAVFFELTPLDALVAHLRER-----------
>tr|D2DIP7|D2DIP7_9BACT SupA OS=uncultured marine bacterium 1k6 PE=4 SV=1
--LYEIVWKDRPLVPGDFKVRQRLQVDEVHRKLFRRMLAPEGGGDPLPEAAVGVEFARWMEW-WRFADHY-LAGPAWVLAA-AEALAAAVVIPDYRRGLR
Q-------ASR-VDSLSVSEGALEEGLLGGRILVGLAFGTFGPE-T---VTEEMVAPAPSGFPATSLATIPTAAIQLAQAAGAEVF-----AQAYLRSLG
AGESLTEAA-MRGARHIGKLTPS--PI----ERGSLRADRTYLVTGGLGGIGCAVAGWLADRGGAI-VLNGRRE--PDA-PAREAISALQ----ARGGTI
RAELADVTDGAAVDAMLARMDASLP-PLGGVIHSVGVLSDAALTNQTWQSFEDVLWPKMLGAWHLHRATADRGLDLFVLFSSGVLGNAGQ--ANHGAANA
FLDQLAGHRR-AQG--GQSIAWGAWAGLGEAERERIAGQLEASGTGWISPRQGLRAFERLVQKDTAGMVASVDWSQAPLLESL-----------------
---------------LATED---------------EVPAEQGDVQADLL-------SGLSLALPEAREQVVSFLQNELQAVMRLNLPPPVAEFSDLGMDS
LMAVELRNRLNRAFAGEYSNTVVFDFPSIAELARHLAGE-----------
>tr|A4U8P6|A4U8P6_9BACT Polyketide synthase (Fragment) OS=Aplysina aerophoba bacterial symbiont clone pAE27P20 GN=supA PE=4 SV=1
--LYETVWQDRPLAPGDFRARQQLQVLPEHQRLFRRLFAGDGGDDPLPESMPRDEFADRMGW-WRFADDC-LASPAWVLAA-ADDLAAEAVVPDFRLGIR
Q-------AARATERLTLPDGALEEGLLGGHVRVALAFGTFSSE-A---VMEEMVAPAPPHVPTTALATMPTAAIQLAHAAGAEVF-----AQDYLRSLG
AGESMGEAP-MRAARHVGKLTNS--PL----ETGRLRQDRSYLVTGGLGGIGCALAGWLADRGGAI-VLNGRRD--PDP-EAVEAIAGLR----ERGVRV
QVELADVTDPEAVDAMLERMDAKLP-PLAGVIHSVGVLSDAALTNQTWESFQQVLWPKMLGAWHLHRATRQRDLDLFVLFSSGVLGNAGQ--ANHAAANA
FLDQLAGHRR-ALG--GLAVAWGAWSELGEAERERIARQLEAAGTGWITPQQGLRALETLIRQDVAGMVAAMDWPSVRFLEEL-----------------
---------------LVVSG---------------RGADEDKESPADLL-------SQLRVSQAAEAEGIATFLQKELQAVMRLTLPALSVGFFDLGMDS
LMAVELRNRLNRAFTGEYSNTAVFDYPDVTKLAQHLAGE-----------
>tr|A4U8R3|A4U8R3_9BACT SupA OS=Aplysina aerophoba bacterial symbiont clone pAPKS18 GN=supA PE=4 SV=1
--LYEIVWRDRSLAPGDFIARERLEVGDHHRRLFRRMLAGDSSGAPLPGGLTSDAVAGDMAW-WRFADTY-LATPAWVLAA-AADLAADAVVPDHRFGRR
L-------GARVADRLILPEGSLDD-FMGGRVRVGLTFRNYGSE-T---VTEKMIVAAPPGFSVSELATFPTAAIQLAQAAGAEVF-----ARDHLRSLG
AGEPVAEVA-MQGARHIGKFTNS--PL----ARGALRGDRSYLVTGGLGGIGCAVAEWLADRGGSI-VLNGRRS--PDP-DVERVIEALR----KRGAEV
RVEIADMTDPPAMDAMMARIDEDLP-PLAGVIHSVGVLSDAAIGNQGWENFETVLWPKILGAWHLHRATENRDLDMFVLFSSGVLGNPGQ--ANHAAANA
FLDQLAAHRR-SLG--GQVIAWGAWSEIGEAERERMSRRSASGGLEWIDPQQGMRAFDRLVREDATSVVLARDWTRPPLLEDL-----------------
---------------LSDGA---------------DD-GADDSLADDLI-------TRLQDAPAAMREDVASFVQGEIKAVLRLRPPAPTVGFFDLGMDS
LMAVEFRNRLNRAFAGAYSNTVVFDYPDIAALSAFLADE-----------
>tr|A0A088YCG4|A0A088YCG4_BURPE Methyltransferase domain protein OS=Burkholderia pseudomallei GN=DP46_3534 PE=4 SV=1
--SPAPYYAQADATDA--------------RRAIEAVRQGAVFANHAIASVPAHRFDEILDQSFSFSGA--ARLGAYAAATIVRSIAPVAAF--WGFWE-
----------TSVEDSALGSFACFERFVGQNPEVEHLMQVLPGEAAPGQPAPAPLRAAPDGAA-------------ASEAAPPDGA-----ADAWLARLT
GPRWDETLIFARGWLRIVDIAEP--DA----GEHVWRDWARYRFDTPAAR-GRRAQIDLADVCRALPVLAGRLP--AADVGSMERVEGVY----RDNPIS
DYFNAVQADIRHVRAWIDAGRREPI-RILE--VGAGTGGTTALALERLRPYAAAIGEDVSAFLAFGARAGYLRTALFDVERPAQRMPAGR--YDIVIATN
VLHATRQVRG-ALRVKGLLEGWWLHEDSSLRESPVLARLLEDEGFGAIAFA-------ARDAHALGQVCATSDGVRQRAGEPS-----------------
---------------GHSSRSTH--------AGEAPAPASAGRAGAAP----------AASPAGTAREPVVAAIHRALQQSLKLARIGDHTPFLDYGIDS
ILGVRFVDSLKQALDVPLNTAVLFDYPTVERLADFIVAT-----------
>tr|E5ARL9|E5ARL9_BURRH Modular polyketide synthase (EC 2.3.1.-) OS=Burkholderia rhizoxinica (strain DSM 19002 / CIP 109453 / HKI 454) GN=rhiD PE=4 SV=
--LLAPQWLVADHASTLPEQHPQIEFLPSLATTIDGIAACAP-FQRLIWLAPQTDFANQRLVSYREGGVYAGGIGEWLGRRIHRKLAALACNRCWGYWGS
V-------GVVAGYRARMAEMAALDQLLAGV----GLIKLLEPMTIAGIDSTQ---------LHCYPLEKPPVWTNAQRLGPPPQH-----HDRLLLALT
ANLLRESLLLDDQGQ----LTAI--PA----AASLWSQWRQASDEWR-RDGDLHAQLQLVETCRALPILRGEKQ--ATEVGSMSLVEDIY----KNNKIS
DYFNEALGEV----DIARRHAEGNR-PLRILEIGAGTGGTTAGLISKLRPWRHQIAEDLSAFLHFAPDAPYLRTAIFDVSKAEQGISTNQ--YDLVIATN
VLHATPDLRC-TLQAKGLLEGWWLYDDEALRICPGLSRLLQSQGFGDIAFP-------VAGSHGLGQIVAVSDGVRLPAQQRV-----------------
---------------MPVADAAI--------APVAIAPVAAIAPRVTPTI------AEGEIDEAVLAKQCRQLITEVLSKLVNIERLQRDVAFDRYGIDS
ILQISLIQALEKATGE-LSRTILFEYNTINQLTDYLLSE-----------
>tr|S0FP35|S0FP35_9FIRM Polyketide synthase like protein OS=[Clostridium] termitidis CT1112 GN=CTER_0304 PE=4 SV=1
----DMGWIIESLDKQAPEWKTAL-VFRDDAGAADVITGLKGSILEVIEVTFGSGYQKTG-QSSYIISGTEEDYLKLMTELKTRDID--KIVHLSTVSRS
-DTMFERSCDDVQNRGIYSLFYLTKALAAYNNEISIDLLSENVEQVTEEDSPD--NAAFFGLGKVAAQENLKLKLKCIDFDQAT------ALDCIINEVI
SECKAQRVAYRKGNRYIPEFSIAELNTSQE--ELNIKNEGVYVITGGAGGLGLEIARYISEKGNTNIALINRSKLPD--AEQWDDIRSIRNI-QTSGSKV
VCCKADISNEEETKEALDSLRERFG-HINGIIHAAGVAGDGFLVIKDSDIFSRVMAPKINGTQILDRLTIDDKMDFFVLFSSMASVTGGMGQGDYTAANT
YLNSFAQRRN-KAGKRTVSINWPGWKETGMTVDNNTDDNFPFRA---LTTSKALNIFEDALRSGRCVIYTGE----LNIP---------------YL---
------------SSVTDSLPVKLSGKISINKYLLD-----KNKTKHQAEVK---DTNAQAAANSASSNSLENKLALIWGSVLGIKEIDVYDNFHDMGGDS
ILATQLLKEIDKEFPEVISISDIFTYPSVSQLAGFISGK-----------
>tr|H2JD34|H2JD34_9CLOT Subfamily IIIC HAD-superfamily phosphatase OS=Clostridium sp. BNL1100 GN=Clo1100_0896 PE=4 SV=1
---------------------------------------------SVIEADIGTSYHRVSEYRYTVGIG-EEDFAKLLRDTMGYGI--TQILYLSKLTSD
----CGEKINQTVSQSIYTMFYLTRALVNSKGALDVVLISGYANKVTGKEEPQ--NTALFGYGKVVGQEYPDLKVRCIDIDDN------MIAKELISEIG
RENKNFLVSYRNGKRYVEVFESVIASEIPQ-NDLVLNKKGVYIITGGIGGIGLEIAKYLASKENINLALLSRTELPEIKDDKNEKIKSLLE-IESTGSNI
AYCRADVTNYEEVSAVINQLRTQ-YTKINGIIHSAGVPGAGLIITKNEDQITKVLASKIIGTYNLDRATESDELEFFVLFSSIKSLLGGEGQSDYAAANA
YLDAYTHYRN-RLGKRTLTINWPAWKETGMAADYGVN---KDNVFKAISTQDGIEAFGKALLSDMERVIIGLDYSD-----PILS-----SEQ-------
------NFIRMSQS--------------LKLKIEQELKKSVSGRNNRAK--EQIHSFVLKGKEGETYTEIEKTVGKIWTEALGLHEINIYDDFYGMGGDS
ILAINIVSGIKNLMNLDINISDFFDNPSVYDFARFIET------------
>tr|A0A0F7A4Q0|A0A0F7A4Q0_PSESY KR domain/HxxPF-repeated domain/Condensationdomain/Beta-ketoacyl synthase, N-terminaldomain/AMP-binding enzyme/Beta-ketoacyl sy
DWFYQRQWQRVNRLRTKPTGREVLVVCSHERLDATTLGSLQGVYRHVIEVQAGNGYQQLGPNRYELDPLDPVAFGRLIATLDQNGASELDWLHALPLSVG
GAVDEQS-LAAAQWACLDTLSALLQAWGQQKSVLRLWLLSWQACPVNGQ-VMRPELAALAGITEVAPQEY-PIRCHWLDLPTAQL---SVQARHLAALLA
EASLPRRMAIRDGYLWQPQLLASPLAN-PMADSNLLPANGTLLVLGGTGGIGRTLCEHLLQSSQRRVVLLSRGGEKQLHA-YASR--------------I
DSIAADIADLARWPTVLEHLRER-YGHFDGVIHAAGTGAGSLIRQRDAQVLSEAMASKTRGMLAVEALIEKMTPGFVLYCSSMSALFGGAGHLDYAAANA
VLDGFTHYRPHANGCVRLGINWDIWRDVGMAAASGVGDDAHQRHLAGLSAQEGCRIFDAAMTAQLPQLLI--------------------------STAD
PET----ARQFYPVRHSVGST------------------LADTAPA------------L-TADTEAPDRLPEHLHDCLCKWLGVSALQPDASLYELGADS
LTLLDLIDELQAATGVVFQLSQFSHKVSLAEVLTLVQASG----------
>tr|A0A060PU50|A0A060PU50_9NOCA Putative non-ribosomal peptide synthetase/polyketide synthase OS=Nocardia brasiliensis PE=4 SV=1
DWLSQPHWVRTRRAGAAPV-NRLLVLVADAPFQPAVVAPFEQTYLRVVQVVPGGEYRRVAPDVFEVDAADSDSLRQVLDVLAETDCAGIEWLHALPLRVS
GPVGPDS-VEHATRACVDTPAALLRVMAEVAQRVRVWWLSAQARPVDGP-VRRPEPNLLAGVCEVGTQET-GVPGSWIDLPGTDP---VEWAAPLAELLS
GASVPKQLALRQGFWWRQQVSPVAAA-------ALPTAAGVHLVLGGTGGIGASAAAWLLDNGAERVVLLARRAQEVLSP-WADR--------------V
EVLIADLVESDL-DGLVRRIGER-VDRLDGVVHAVGVAAGGLIARRDPAAARQWSAAKLRGALLTERLIQLHRPAVAVYCSSMAAWFGGIGQLDYAAANA
LLDGFAGYRGGAETTVRVSIGWDVWRETGMALRALPTDPRHRAHLAGLTVAEGQRVFARALGAQLPQLLV--------------------------CTTD
LDD----ARAFYAAAPTDTAA------------------G------SA---------V-------ALESAQQLLRAELCEVLGLDELDRNASLYDLGADS
LTMLDLLDTIKQQFGVELELARLSHRVCLDEIVSRLAE------------
>tr|A0A0N0E3N2|A0A0N0E3N2_9PSED Amino acid adenylation enzyme/thioester reductase family protein OS=Pseudomonas fuscovaginae GN=PF66_03410 PE=4 SV=1
DWFHQRQWVRLRRLGSGSPRRGTLVVCANEALDGGLLDALGRVYRRVVQVRAGNGLRRLAADRFELDPGDSQALTALLAELI--AVEELDWLHALPLSVG
GAVNEQS-LAAAQWACLDTPSALLQAWGEGALKLRLWLLSWQACAVNGE-VRRPELGALAGVCEVAPQEY-PLRVHWLDLPGSQW---ADQAGTLAALLG
DAALPRRLAIRGDYLWQPRLIASPAPA-SLPASPLLPATGTFLVLGGNGGIGSSLCEHLLQAPGRRVIVLSRRGEQNLRD-YGDR--------------V
EVVQADIADLARWPSVVEQLARR-YGELVGVIHAAGIGAGSLIRHRDARQMDSAMAAKTLGMLAVEMLITRLSPGFVLYCSSMSALLGGAGHLDYAAASG
VMDGFAHYQPEASRCVRLGINWDIWRERGMATAVSAGDEAHQRHLAGLSVEEGAKVFDLALALQLPQCLI--------------------------STTA
IEA----SRGFYPRRHTAVPE------------------VV-------------------APSVERGPDPAAHLGECLCQWLGVDTLDDEDSLYELGADS
LTLLDLIDEVQSRLGIGLQLSQLSHKVSLREILTLIEGSG----------
>tr|A0A0N0WHQ1|A0A0N0WHQ1_PSEYM Non-ribosomal peptide synthetase/polyketide synthetase OS=Pseudomonas syringae pv. maculicola GN=AC504_1525 PE=4 SV=1
DWFYQRQWQRVRRLGTQPIRRDRLVVCSHERIDAALLGSLQGVYRHVIEVQAGNGYQQLGPNLYELDPLDPLAFSRLIAELDQSGATELDWLHALPLSVG
GVVNEQS-LAAAQWACLDTLSAFLQAWGEQKTALRLWLLSWQACPVNGQ-VMRPELAALAGITEVAPQEY-PIRCHWLDLPTAQW---GSQALQLASLLA
ETSLPRRMAIRDGYLWQPQLQPGPLAL-PKVASNLLPVNGTFLVLGGTGGIGRTLCEHLLRSSQRRVVLLSRRGEQELGD-YAAR--------------I
DSVQADIADLARWPKVLEQLRER-YGHFDGVIHAAGTAAGSLIRQRDAHLLSEAMASKTRGMLAVEALIEQMTPGFVLYCSSMSALFGGAGHLDYAAASA
VLDGFAHYRPNANGCVRLGMNWDIWRETGMAAASGIGDEAHQRHLAGMSAQEGCQVFDAAMTAQLPQLLI--------------------------STTD
LNT----ARQFYPARHSGGLT------------------LVDTAPA------------V-AAET----GLPERLHGCLCKWLGVSALDPDDSLYELGADS
LTLLDLIDELQAATGVVFQLSQFSHKVSLREVLALVQSAQ----------
>tr|A0A0N8QR03|A0A0N8QR03_9PSED Non-ribosomal peptide synthetase/polyketide synthetase OS=Pseudomonas caricapapayae GN=ALO80_04886 PE=4 SV=1
DWFYQRQWQRVRRLGTQTNLRGVLVVCAHERMETAVLGSFQSVYRQVIEVQAGNGYQQLGPNRYELDPLDPLAFSRLIATLEHNGATELDWLHALPLSVS
GVVGEQS-LAAAQWACLDTVSALLQAWGAHKTALRLWLLSWQACPVNGT-VLRPELAALAGITEVAPQEY-PIRCHWLDLPAARL---DTQARQVAALLA
DTSLPRRMAIRDDYLWQPQLQASPLAE-PAAVSNLLPANGTFLVLGGTGGIGRTLCEHLLQSSQRRVVLLSRRSEQSLHA-HASR--------------I
DSVQADIADLARWPGVLEQLRER-YGQFDGVIHAAGTGAGSLIRQRDARVLSEAMASKTRGMLAVEALIEQMKPGFVLYCSSMSALFGGAGHLDYAAASA
VLDGFTHYRPNANGCVRLGINWDIWRDIGMAATAGIGDEAHQRHLAGMSAQEGCRVFDAALTAQLPQLLI--------------------------STTE
LNT----ARQFYPARHGGDST------------------LVEAAPA------------F-AAET----GLRERLHGCLCKWLGVSALEEDDSFYELGADS
LTLLDLIDELQAATGVVFQLSQFSHRVSLREVLTLVQQAA----------
>tr|A0A0F4QXF9|A0A0F4QXF9_9GAMM Uncharacterized protein OS=Marinomonas sp. S3726 GN=TW85_14780 PE=4 SV=1
DWFLQESWLRGESLEGNKAFNKHYVLIDNPNQQGKQLAETQVRYFS--NL----------LETHELEPLE------------NFN--A-SYSSTLSQGLS
NDSDLAPFGFKQIFNDWNDLINLIQSKLISKQSIKIINLVQGSAQILGE-SLNPTSALLLGLLQTCPIEFENLKYTVLDLPPTSEK--LIL-NALLKLE-
-SLSSGHYAIRGHFLWQKHYQRSINVFEKTEALDKKGRKEKVYVLTGIGGIGEALIKHLSKDSNNKLICLSRSSMT--LD-TKLA--------------V
NRLKCDITDLMSMKWVKQQIQAS-FGDVYALVHLAGKSGSGMMRLLDSEKTIDKMSAKVLGAINVEKTLLSLKPKKVMYFSSMSCVNAIAGQTDYCASNH
FLDLLAKHQNQVPDTEFISVNWPTWQGTGMASEV--------ERNDAITPEQGASLFSSTLEQGSSQYLI--------------------------SPLS
DHD----KTAFFKEINSNLIP----------------------Q--------------R-AVENKEAQTLESLITNLFKDCLGLDDISKEVCFYDLGGDS
LTVLDLFDALEASFPGKISLKELNQNVTIDRLTKLISNDE----------
>tr|U4DV52|U4DV52_9VIBR Putative Polyketide synthase (Fatty acid synthase/beta-ketoacyl synthase) OS=Vibrio nigripulchritudo FTn2 GN=VIBNIFTn2_1340037 
DWFREECWQRATKVSQKET--PTLVYNSELTHCPHLSEVFHA---NTVEVTTIE------------------AFKASLEILSEKNWQGVEL---------
------------IQACLSAPHNME---------VSLVCLFKGVADVTGE-ALIPENSTVLGLANTVSIEQPNLSLACLDVTDSAST--SQLSAGIATLFK
QAEHINLYALRGRYLWKPTYQPYHFYRLPYNKEVAMPDSGVYIVTGGTGGIGQHLCEYLSNLENNVVISESRNASDSSLS-TQPG--------------I
QTVQCDVSDSEQWHTLIDSVATT-FGKVTGIVHAAGSAGGAMLHSATASTIESSQNAKIAGAQNIVNSARQYHPEFVVLCSSMSSVYPVAGQTDYCAANT
FLNQLAVSENQSS-VRYISLNFPTWAKTGMAKAV--------EDTAAITPEEGVRVFERAVESGEGVIYV--------------------------SPLK
PKS----AQAFFHRLNSKERT------------------SN-----------------I-EHSDCANSNVREQLTRIFSEVLGMDESETDVCFYDLGGDS
LTVLDLFDELNATFPNQFSLAELNHNISIDRLVEKLECGA----------
>tr|A3YFF7|A3YFF7_9GAMM Amino acid adenylation OS=Marinomonas sp. MED121 GN=MED121_00695 PE=4 SV=1
QWIMKESWQREKRLSANKYSAANYIIIDDLADNGTLLAEAQSHIQQQTQLQTQQELIYPSLDKINYEEIS-----QRLAINAQFN--PHSYHDTTPVNL-
--DDYSHSYSDSYYLSWCKLIRFFKTWSSLNTSLEFINLVQGSAEVLGE-DIRPEVGLLLSFSQTLDIEFDHLRYRVLDLEPSYQC--DNLSQAIPVLA-
-NSDQAHYALRGQYIWRKTYQTCHDTLPTATRVNKTEQTVIYLVTGGTGGVATAITETLLSQANTRVISISRSKGA--LD-PTQV--------------L
NHIKCDVTDIMAMEWLSTLIKET-FGKITGVIHTAGAPGTGLIRLLDEDQATQNMAAKIQGAINIEKTFVKLKPQIVMYCSSMSVIDAIAGQTDYCAANH
FLDLIAKKQNQTNSTQFVSINWPTWNKTGMAKDI--------EPTAAINQRQGQSLFKKLISAQDNQYLI--------------------------SPLD
RDN----RSRLFSQINRKNEL------------------NVDAI--------------H-KTEANNTASIRTYLDSLFKTSLGLEEIDHNRCFYDLGGDS
LSILDIFDALQKRFLSKVTLADLSHEVSINRLLSLLETSS----------
>tr|A0A0Q7VFN9|A0A0Q7VFN9_9ACTN Non-ribosomal peptide synthetase OS=Streptomyces sp. Root55 GN=ASD51_28625 PE=4 SV=1
RWMHQPQWTRLRRARTDESVTRTAVIVAGGRTDPAAWRELERRYARVVWLVPGKDLIRIDDDHYEADPADAGHLAAVLAEASAPGGTAVDWLHALPLAID
GDVGERS-LDTARWACLDTVAALSRAVADRRDRPRVWLLSCGAQPVTGP-VRRPEAGLLAAATQVPNQEL-GAELRWLDLPGPDP---TAWSAFLPDLFL
DPPETSVVALRDSFWWHRAIHPVAALR-TESREAWAWGTGTYLVLGGTGGIGAVIAARILRRPESRLVLLSRNALPALTP-WSDR--------------I
TLVRADLAAEET-GDIAARLAPHLDSGLAGIVHAAGTAAGGLIALREAESARAGTDAKLRGALLMERLIDAYDPGHAVYCSSMASLFGGVGQFDYAAANG
CLDAFAHYRAGNTRTVRTGIGWDIWREAGMARSALGHDEQHRRHLLGLTSDEGAAVFEQAMRLQLPHLWV--------------------------NTTD
LSQ----ARSFYERPPTAVET------------------ARGPA--EG--------AQP-TPHLPPGRDRVAQLGDVVAWLLGVDDVGTDVSLYDLGADS
LMLLELVDQIKQRFGTDLDLSRFSHRVSVAEIADLIDATA----------
>tr|M9TPD2|M9TPD2_9ACTN Long-chain-fatty-acid--CoA ligase OS=Streptomyces sp. PAMC26508 GN=F750_0334 PE=4 SV=1
RWTHQPQWTRLRRARTDVSPTRTAVIVADERTHPMAWAELERRYTRVVWLLPGKDLVRIDDDRYEADPSDTGHLAAVLLEAGAPGGTAVDWLHALPLAID
GDIGEES-LDTARWACLDTVAALSRAVADR-DRPRVWLLSCGAQPVTGP-VRRPEAGLLTAATQVPRQEL-GTEMNWIDLPGPDP---APWAAFLPDLLL
DPAETSAVALRDSFWWHRAVHPVAARS-DTRGETGARSIGTHLVLGGTGGIGAVLAARILRHPENRVVLLSRHALPALEP-SRDR--------------I
TLVRADLALEEP-ADLADRLAPHLGGGLAGIVHAAGTAAGGLLALRDAETARRGTEAKLRGALLMERLIASHHPGHAVYCSSMASLFGGVGQFDYAAANG
CLDAFAQYGGDDTRTVRMGIGWDVWREAGMALSALGHDGQHQRHLLGLTSDEGAAVFDQAMRLQLPHLMV--------------------------NTTD
LAQ----ARSFYERPATTEET------------------PHPPT--EA--------ARP-T----PGHDRVAQLVDTVAPLLGVDDVATDASLYDLGADS
LMLLELADRIEQRFGVDLDLSRFSHRVSVAEISGLIDAAA----------
>tr|A0A066UCL1|A0A066UCL1_9PSEU Peptide synthetase OS=Amycolatopsis rifamycinica GN=DV20_11295 PE=4 SV=1
QWLHQPTWVRLRRAGDAVSSGRTLVLSGEGPLTAP---ALDAAYARVVRVHASDHFARRDTDTFEADPADTAHLRRVLDALP---DTGIDWLHTLPLGIT
GPLGEAS-LRQAQWACLDTPAALLRAAHD--RPLRTWWVSAGAAPANTP-VTRPEAGLLAGITAVGPQES-GIPGHWVDLPTPGL---DGL----ADLLT
GPTPPERVALRAGFWWTQESAPVTA--------EPSTMDGTVLVLGGTGGIGTAVAEELLTRTTSRVILLARDPREPLEP-WADR--------------V
DLLAADLTKTTA---------DEIPGPLTGIVHAAGSPGGGLIATRGEGT----QDVKLAGALLTEELIERDRPAFAVYCSSLSAQFGGTGQLDYAAANG
FLDALAHREG---ATALLSIAWDVWRDSGMAVTALETDARHQAHLAGLSDDEGRRTFARALGTGLPQLLV--------------------------ATTG
LDT----ARTFHERETTPAK------------------------------------------------PAEADLTEEVRALLGVAELDPDVPLYDLGADS
LTLLDVVDSVKRLYGVDLDLAWLGPEVTMAALLAKLDAAA----------
>tr|C6WEG6|C6WEG6_ACTMD Amino acid adenylation domain protein OS=Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971) GN=Amir_3
EWLRQPTWIRLRRTAGATRTDRVLVISGEGPLTAP---ALDAAYPRVVRVHAAERFARLGPDAFEADLADTACLRRVLDSLP---AQEIDWLHTPPLGIT
GPLGEAS-VRHARWACVDTPAALLRAAHD--RPLRTWWVSAGAAPATTG-VTRPEAGLLAGVGAVGPQES-GIPGHWVDLPGPDL---APL----ADLLT
GPTPPARVALRAGFWWAEDDAPVRA--------EPLAVDGVHLVLGGTGGIGAAVAEELLTRGAGRVVLLARDPRDALTP-WADR--------------V
DLLAADLTTVTA---------DAIPGPLAGIVHAAGNPDGALIATRGEGT----QAVKLAGALLVEQLVERDRPAQVVYCSSLSARFGGVGQLDYAAANG
LLDALAHRDG---PTARLSIAWDVWRDTGMAVTALRTDARHQAHLAGMSAEEGRRTFARALDACLPHVLV--------------------------ATTG
LDN----ARAFHERETAPTAS------------------PA--------------------------GDAGAELTEEVRALLGVAELRPDVPLHDLGADS
LTLLEVVDAVKRLFGVDLDLAWLGPEVTMAGLLAKLAEAG----------
>tr|A0A0H3D460|A0A0H3D460_AMYMU Non-ribosomal peptide synthetase/polyketide synthase OS=Amycolatopsis mediterranei (strain U-32) GN=AMED_3962 PE=4 SV=1
AWLHQPTWVRLRRATTAAPTDRVLVICGEGPLTAP---ALDAAYPRVVRVQAADRFARPSPDTFEADPADTAQLRQILDVLP---DTGIDWLHTLPLGIA
GPVGEES-LDRARWACLDTPAALLRAAHD--RPLRTWWVSAGAVPANTP-VTHPEAGLLAGVTAVGPQES-GLPGHWVDLERPDL---DRI----ADLLT
GPTPPERVALRAGFWWTQGSAPVAA--------EVELHDGTYLVLGGTGGIGTAVAEELLTRTSGRVILLARHPFEALKP-WADR--------------V
DLLAADLSTVTA---------DEIPGPLAGIVHAAGTPAGGLIATRGAST----PTGKLAGALLVERLIERDRPDFAVYCSSLSAQFGGAGQLDYAAANG
FLDALAHRDG---PTARLAIGWDVWRDSGMAVTALETDTRHQAHLAGLSDEEGRRTFARALATGLPHLLV--------------------------ATTG
LDA----ARAFHEREATPVK------------------------------------------------PAAADLTEEVRALLGVAELDPDVPLYDLGADS
LTLLDVVDSVKRLYGVDLDLAWLGPEVTMSALLAKLAEAA----------
>tr|A0A0P9Y0F6|A0A0P9Y0F6_9PSED Non-ribosomal peptide synthetase/polyketide synthetase OS=Pseudomonas syringae pv. primulae GN=ALO52_05082 PE=4 SV=1
DWFYQRQWQRVRRLSSRPLPRELLVVCSHEALDDTLRSCLKNVYRRVVEVTAGNGFQRLATDRFVLDPLDTLALTRLLDILAGDQPLELDWLHALPLSVT
GRVNEQS-LAAAQWACLDTVSALLQGWGKRTPALRLWLVSWQACPVYGE-VKRPELAALAGITEVVPQEY-PVRCHWLDLNSAQL---AARPEALAALLA
DAAAPRRMAIRDHYLWQPHLQASPVMA-STVDPCLLPQDGVFLVIGGSGGIGRTLCEHLLRNDQRRVVLLTRHGEDALQA-YRSR--------------I
DPVQADIADRTVWPQVLEQLERR-YGHFDGVIHAAGVGAGSLIRHRDARTLSEAMAAKTLGMLAVEELIQQMTPKFVLYCSSMAALFGGAGHLDYAAASG
TLDGFTHYHPNASDCVRLGINWDIWRDIGMATGAGAGDAVHQRHLAGMSAQEGCQVFDMALSAQLPQLLI--------------------------STTS
IET----ARQFYPVRHGASAA------------------AQPVAQASA--------STA-PGKEEQGADLRTRLHDCLCKWLGVTELDEDDSLYELGADS
LTLLDLIDELQAATGEVVELSRFSHKVSLREVLALVHADS----------
>tr|G8XGR6|G8XGR6_STREN Amino acid adenylation domain protein OS=Streptomyces cattleya (strain ATCC 35852 / DSM 46488 / JCM 4925 / NBRC 14057 / NRRL 80
DWLHQPHWARLHRAAT-TA-TRLLVIVTGEPLPAPAVHAFQEVYARVVRVVAADAFARHGQDEYRADPADPESLRLLLDAVADAGADGIDWLHALPLAVT
GPVGPKA-LDRARHACLDTPAALVRAVAAGTPPVHPWWLSYRARPADGP-VRRPELGLLAGAAQVTAQES-SLDGHWLDLPGADP---ADWAAPLAALTA
GQDTARELALRQGYWWHQVTLPVPAP-------DLPADGGDHLVLGGTGGIGTAVAAWLLDHTDGRVLLLSRTPRDELTG-HADR--------------V
TLVEADLATTPA-PDLAALIAGH-TSRLHTVVHAAGVPSGALIATRDATAMRAGTAAKLDGALLMEEVIARHRPRLAVYCSSMSALLGGVGQYDYAAAAG
LLDAFAHHRPDDTATTRVTVDWDVWREAGMALRTSRTDPRHQAHLAGLTVAEGKRVLARALGAGLPQLLV--------------------------SVTE
LEE----SRVFYTPPATEAPA------------------T------AP--------AR-------PATTPAGLLTDWLCRWLDVDHLDPDAPLYDLGADS
LTMLDLISEVKRHFDVELDLASFSHRVSLGEIVSLLAGPV----------
>tr|A0A0M9XJ16|A0A0M9XJ16_STRRM Peptide synthetase OS=Streptomyces rimosus subsp. pseudoverticillatus GN=ADK70_35525 PE=4 SV=1
DWLHQPHWVRLSRAVPAPAPGGLLIVMTAEPLPPEALRFFEAGWSRVVRVGAADAYARLTDDVYEVDPADPASLRQLLDALGGPGETVIDWLHALPLAVD
GPVDEDA-LTRARWACLDTPAALLQAVAGLAEKVRPWWLSYGAQPVEGP-VRRPELGLLAGVCEVAPQEC-AVDGRWLDLPSREL---ADCAQQLAALSG
RGTLPRRLALRQGYWWQQALLPVPAPT-SA-PSVLPDEAGTYLILGGTGGIGSSIAAWLLERSDCRVILLSRQPRAELTA-WADR--------------V
ELVEADLAETPT-ETVLTRIDAV-AHRIDGIVHAAGTAAGGLVTRRDAPAMRQAMAAKLHGALLAERLIERHRPAFAAYCSSMAAQFGGIGQFDYAAANG
LLDGFARHRAGEEATLRIGIDWDIWSEVGMARDALRTDARHQAHLAGLAVKEGRQLFARALELQLPQLLV--------------------------STTP
IEE----ARAFYAAPADAVSP------------------VTPGT--AT--------AS-------ATASASAELTDWLGRWLGLDELDPDASLYDQGADS
LTMLDLIGKVAEHFGVDLELSQLSHQVSLNEVLVKAGAEP----------
>tr|A0A0P9Q888|A0A0P9Q888_9PSED Non-ribosomal peptide synthetase/polyketide synthetase OS=Pseudomonas coronafaciens pv. garcae GN=ALO77_04770 PE=4 SV=1
DWFHQRQWQRVRRLNQNMPRRDMLVVCSQERLDSTVLGCLSEVYRQVIEVCAGNGYQRLGPDRYELDPLDSSAFSRLIAELTQRALTELDWLHALPLSVS
GAVNEQS-LAAGQWACLDTVCALLQAWGQRTMVLRLWLLSWQACPVNGD-VQRPELAALAGITEVAPQEY-PIRCHWLDLPEPRL---SLYARPLAALLA
DALLPRRMAIRDDYLWQTRLQASPLVA-PATVSNLLPVDGTFLLLGGTGGIGRTLGEHLLQSSQRRLVVLSRSGNDNLLG-YRSR--------------I
DLIAADIADLARWPAVLDSLRQR-YGRFDGVIHAAGTGAGSLIRQRDAQTLAASMASKTLGMLAVEELVKQMTPGFVLYCSSMSALFGGAGHVDYAAASA
VLDGFAHYRADSDTCVRLSINWDIWRDIGMAAAEGVGDAAHQQHLAGLTAQEGGQVFDAALGAQLPQLLI--------------------------STTR
LET----ARQFYPLRHGASSP------------------TD-----------------I-KLAGQSDTDLRERLQDCLCKWLGVPSLDEEASLYELGADS
LTLLDLIDELQAATGEVLQLSQFSPTVSLREVLMLVQSSE----------
>tr|J2X6U7|J2X6U7_9PSED Amino acid adenylation enzyme/thioester reductase family protein OS=Pseudomonas sp. GM25 GN=PMI24_04890 PE=4 SV=1
DWFHQRQWVRTRRLSGNATAREVLILCSHDAPESTLLASLNIVYRRVIQVRAGNGFKRLSPDRFELDPLDTEALNRLLAEVA--ELGELDWLHALPLAVS
GAVSEQS-LDLAQWACLDTVSALMQAWGQRTTRLRLWLMSWQACPVDGA-VQRPELAALAGITEVVPQEY-PVRCHWLDLPSSRL---EAQACELAALLG
DVSLPRRMAMRDGYLWQPRLMPQPLTG-PTTTSGLLPEDGTFLVLGGSGGIGRTLCEHLLQAPARRVVLISRQGQESLAA-YASR--------------I
DCIKADIADLPRWPQILDQLAVR-YGRLSGVIHAAGVGAGSLIRHRDPRKMAEAMAAKTRGMLAVEALIEHLTPGFVLYCSSMSALFGGAGHVDYAAASG
VLDGFTHYRPNPDTCLRLGINWDIWRDIGMATTSNGGDAAHLEHLTGLSAEEGCRVFDLAMATQLPQLLI--------------------------STTG
IDT----ARRFYPVRHGAATP------------------VE----------------------APKGVDLSVRLRDCLCKWLGVAELEDDDSLYDLGADS
LTLLDLIDELQAATGEVFQLSQFSHKVSLSEVLGLVSTAT----------
>tr|A0A0L6FSM4|A0A0L6FSM4_9PSED Thioester reductase OS=Pseudomonas sp. 250J GN=DA83_25030 PE=4 SV=1
DWFHQRQWQRVRRLRKSMAVRQTLVACVHEAVDDAVLATLGRAYRRVVQVQAGQGYRQLATDRFELDVLDTQALGRLLEALP----GELDWLHALPLSVT
GAVDEQS-LAAAQWACLDTPSSLLQAWGQRDADLRLWLLSWQACPVQGA-VARPELSALAGVTEVAPQEY-PLRCHWLDCPSPSL---GEHANTLATLLA
EEALPRRMALREGYLWQPRLVPSPL---PSPAAPGLAERGTYLILGA-GGIGRTLCQHLLRAADRRVVLLSRSPV--ADL-DHER--------------V
DWVQADLADLQRWPQVLEALARR-YGRFDGVIHAAGIGAGSLIRQRDARQMAIAMAAKTHGLLAVEALIARMAPDFVLYCSSMSALFGGAGHLDYAAANA
VLDGFSHYRAAGEGCLRLGINWDIWRDTGMATRGNGNDAAHQQHLKGLSAQEGCEVFERAMAAQLPQVLV--------------------------STTA
LHS----ARRFYPRRHGAAAP------------------VD---------------------ERPRQDDLPTRLRDCLCQWLGVDSLEDDDSLYDLGADS
LTLLDLIDELQRATGVVVQLSQFSPHASLREVLALVDADP----------
>tr|A0A0F7XY92|A0A0F7XY92_9PSED Thioester reductase OS=Pseudomonas sp. CCOS 191 GN=CCOS191_2530 PE=4 SV=1
DWFHQRQWQRVRRLATAAV-QRTLVVCAHDAADEGVLATLGQACQRVVHVRAGKGFRQLAADRFELDVCDAQALGRLFDALP----GALDWLHALPLSVS
GAVDERS-LATAQWACLDTPGSLLQAWGQRDASLRLWLLSWQACPVQGA-VARPELAALAGVTEVAPQEY-PLRCHWLDLPSPAL---GAHASALATLLG
EEALPRRLALRDGYLWQPRLVPSPL---PAATAPSLAHTGTFLILGA-GGIGRTLCQHLLRAEGRRVVLLSRSPT--VDM-DHPQ--------------V
DWVQADLADLTRWPQVLEDLACR-YRHFDGVIHAAGVGAGSLIRHRDAREMATAMAAKTRGLLAVEALIARMTPGFVLYCSSMSALFGGVGHLDYAAASG
VLDGFAHYRATAEGCLRLGINWDIWRDTGMATRTHGSDAAHQQHLKGVSAAEGCEVFERAMAAQLPQLLV--------------------------STTS
LGT----ARRFYPVRHGVAAQ------------------PQGV-------------------VQASGSDLAARLRGCLCQWLGVDALVDDASLYDLGADS
LTLLDLIDELQGATGQVVQLSQFSPQVSLGEVLALVADEP----------
>tr|Q1IA16|Q1IA16_PSEE4 Putative Polyketide Synthase (Terminal component) OS=Pseudomonas entomophila (strain L48) GN=PSEEN2718 PE=4 SV=1
DWFHQRQWQRMWRMAGPAPVRQTLVVCSHAAADETLLGTLGAAYRRVVHVRAGDGYRQLAANHFELDVLDAQALTRLLAELP----GDLDWLHALPLSVG
GAVDERS-LATAQWACLDTPCSLMQAWGQRDANLRLWLLSWQACPVQGA-VARPELTALAGATEVVPQEY-PVRCHWLDCPSPSL---LEHAKPVAALLA
EDALPRRMALRDGYLWQPRLVPSPL---PLAAPNTLPDHGTFLILGG-GGIGRTLCQHLLRAPGRRVVLLSRSATEAWQV-DRER--------------V
EWLQADLADLMRWPQVLEHLAQR-YERFDGVIHAAGVGAGSLIRQRDAERMASAMAAKTRGMLAVEALIARMNPGFVLYCSSMSALFGGAGHLDYAAASG
VLDGFSHYRAPGQGCLRLGINWDIWRETGMATEASGNDAAHQQHLKGLSTQEGCEVFDRAMTAQLPQVLV--------------------------STTA
LAH----ARRFYPVRHGATAP------------------VE---------------------VPPKQDALPARLRDCLCQWLGVDALQDDASLYDLGADS
LTLLDLIDELQRATGVVVQLSQFSPTVSLREVLALVGNDP----------
>tr|I2C4I8|I2C4I8_BACAM Polyketide synthase type I OS=Bacillus amyloliquefaciens Y2 GN=mlnG PE=4 SV=1
---YKPEWTESFIPSKSVPLTGLLLIFAENE---RQIQELSGLGCTLLFVIRGKEFAVLHDDTICMNHVKKHDYLKLFRYIHDHYQLPEKILHLWSDSQA
D-MSKGGIQKQ-LENGLFSLLYITQALIELKKIIKLTHIFQTE-N-KEQLP---LHHALGGLVKTVHQEHPNFHYQIINITQSEGA-GAALPAIYQREFD
EKRDIHFEVYENGRRFTKSYN----KAGSFDLTQPLKHHGNYLITGGLGGLGYILAKHLSEKWKANLILTGRSD---LTEEQEKKIEYLRS----SGSTV
EYIRSDVSKQSDAERIFAFAKEQFG-TLHGVFHSAGVLRDSFILRKTKEEIDQVTGSKVYGTLWLAEEIKKMKVELLVLFSSTSAVFGSAGQCDYAFANA
FLDQYAAVMT-AKAERVVSVNWPLWTSGGMNIDDEVSYMKQELGLDPLDDSDGIQALENSLCQSSE-------------QLIA--------------LKG
------RKEKI----EDVLKR--AG------TISFHLKQQEDADLQ----------------NDELRQNIISYLKNIMSEELKLSLIDEKQYLEKYGIDS
VMIMRLTKKLEQSIG-RLSKTLFFEYHSISQLAEYFLSH-----------
>tr|I2C4I5|I2C4I5_BACAM Polyketide synthase type I OS=Bacillus amyloliquefaciens Y2 GN=mlnD PE=4 SV=1
---YQTVWQRTDLSIVGGRREGSLLLFDKNE---IVRNELAALDTRVILVKPGKEFRKTGDGVFEIDPRSERDYINLLGWLIEEESDIREAVHLWSDMPF
E-KTERAIREQ-CDSGVYSLFLLQQALFKNNKPIKLLYGYFSH-L-SGEQP---LYAAASGFLRTLQLENPLISAKSIELEQSIAA-VH----IIRNELS
DFQPSDVEIYKMQRYVKQLKTYE-PEKNSRSGDVPLRENGVYIIAGGAGGLGFTFAEYLAFQTKCCLVLTGRSP---LSDHIRKQLRRLED----AGSSA
VYVQADITNKEEAEYVVKKAKTSYG-KVNGVIQGAGIIRDSFLLNKSREEFDQVIRPKVLGTMWLNDAVEKENPDFFICFSSTSAVLGNVGQSDYAFGNS
YMDHFMNMRS-AQDTISLSLNWPLWKEVGMQVDERVETMK-KAGFYPLEKEEGKEAFAVALSSGFS-------------QFTV--------------FYG
------DEQ-I----DNHV------------IQADEGTGRNIESFD----------------SEKLTAETSDFIIKMIAAEFRMDKIDAEEALEKYGLDS
VMIINMTNELEKHFG-ALSKTLLFEYQTAAELSQYFVEE-----------
>tr|M4KVF4|M4KVF4_BACIU Polyketide synthase OS=Bacillus subtilis XF-1 GN=pksM PE=4 SV=1
---FQEVWKEEPATLT-SKRIKTLICFLTEREQNAFASVLKNVDQTKVIFSQGEVYSKQSEYSYQIVRQEPVTFEKAFQSIKEELGEPDAILYMWPMEDK
R------CIKDH-----SCIVYLLQGMSAKLHPSRLLLAGCFED-----GLDRSYLESWIGFERSLGLVLPHTK--VTGIFQPAEVSMDDWTRKIWAELQ
ASAE-QTVLYQNAKRYVNHIEQTTIQ-PD---DSKLKSGGTYLITGGVGGLGYLFAKHLAKNYAANLILTGR---SPFNDEKQKQIKELND----LGGEA
MYAEADVSDPIAMGDCVKRGKDRFG-AINGVIHAAGIESDSAIFDKKIESFQRIIEPKINGTIALDEWLKNEVLDFMCYFSSSSAVLGDFGCCDYAIGNR
FQMAYAQYRNLH-NGKTFVINWPVWKDGGMKIGDETDMYLKSSGQRFLEAEEGIRMFEHILAQ-QDAVIAGQ---------------------------L
S-----RVSRFLGMTEPAIPEPA-TQAPLAQEN-------------------KDEVKTLS-----VEKRLEHDLKEHIHTLLKIDKLNLNKNWADFGFDS
IYLAKFSNVLSKHFNIEVTPALFFGYSTLQELIGFFLTD-----------
>tr|W7YI66|W7YI66_9BACL Malonyl CoA-acyl carrier protein transacylase OS=Paenibacillus pini JCM 16418 GN=JCM16418_1328 PE=4 SV=1
---FEEVWKEEPLQQNSGSRVNTLVCFLSDVEQKTAVQFFRTIEEMKVLFSQEESNGESSSTIYRVDRHDVDTYDRAFKDIQEQHGDIDAVLYMWSLEDP
G------SVQDY-----SHIVFLLQAVLAQSKPRRLLLAGQFGQE---ADLSRCYLESWIGFERSLGMIMPQTK--VSGVYKEVAGDIADWLRKLWSEVH
AETA-RTAFYQGEKRHVSHIKPTLLQ-AD---HSRLRMNGTYLITGGCGGLGFLLAKHLAKRYKANLILTGR---SPMDPKKEAILGQLVA----LGSRA
HYIQADVCDVQAMNTGLSESREHFG-SIHGAFHAAGLQSSQSFEEKELSKFHEILSPKIQGTLVLDELMQEDYLDFICYFSSSAAILGDFGFCDYAVGNR
FQMAYAKYRNRQSSGRAITINWPVWRDGGMSIGDATENYLRSSGQRYLETEEGLDILERALFQPQLQVLAGQ---------------------------A
S-----RVHRFLGLSEETRQKDQPAARPQGKGR-------------------QAHMLGWS-----TEQCLEADLKNWISELLKHHKLKPDIQWMDYGFDS
VLLAEFASYLSDRYQVEIAPSLFFSYTNLEQLIRYLLKK-----------
>tr|A0A0M9EDL8|A0A0M9EDL8_9DELT Polyketide synthase (Fragment) OS=Candidatus Magnetomorum sp. HK-1 GN=MHK_000659 PE=4 SV=1
-----------P---EKANFLNQLLCDFHEKD---------------IWHYSGNKLKQLSEKKWIIDTKTKDFFDGGYNTINSEQP--------WIDQSK
N------QEKGV-----LCLFKMIKALIEQLIDHKIQLVV-FTQGGQYNQVTNPFPASLYGFCQSLQKEHKKLDVYCLDLHNGEP--LMDVLKAFIRNQQ
----ECEMVIDSDDCYVRSLNRLQLK-PP---CNNFRKKGVYLILGGAGGIGLSLARYLSEKYQANLVLIGR---STLNDHKMQAIAEIES----LGGKV
KYICADARNFEAMKDAVKQAKEAFQ-TIHGVVHSAIVLRNRTIKNMDESAFGEALAPKIDGSIHLYEAIKNEPLDFIMFFSSAASVIATAGQSNYVAGCT
FKDAFAFFLSNQVKYPVKLINWGYWGSVGIIANKWYKDRLKNEGILSIEPHEGMKIIERVMAYPVPQVLTGQ---------------------------K
NYINNSRFCRFFTYNEITKKTPFTSVTPVEYAPEDKKSF-------SQPVVNALEISETD-----LKDHTQNYIKEVFSKVLKLAHFEGDENFDMYGVDS
LLTMKITDALETDFGHELSATLLYENPSIDQLTSFFLKH-----------
>tr|C7PSF9|C7PSF9_CHIPD Erythronolide synthase, Beta-ketoacyl-acyl-carrier-protein synthase I OS=Chitinophaga pinensis (strain ATCC 43595 / DSM 2588 / 
---IHKTWEEQVINT--SNAFHGKLLVLATTPQYNDIDI---------IDVSSALPEGGMP--------------GL--------------------IDL
G------C-DEAAE-QALTGLALLQQLISGNR--PLT-MIGVTQGLEGGKSSGQTGALRAGLFRMLQAEYRYLNAIHLDIEKEGS------AAHILSELR
V---APEICIREGKRYRAVLTAKKIK-DN---IPAFPAGGVLLVTGGTRGIGLECARHFVKKYGAKVVLTGR---EALPPEKLKAIQALRA----EGVTV
WVRAVALDDATAVNTLMAEIRTSLG-NIGGVLHCAGMVDNPAFIRKSVHAIREVLVPKVAGLRSLFQSVSKDPLQFFVLFSSVAGIIPTAGQSDYAMANA
YMDYFAAAA--QASFPVVSIQWPSWKETGFGEV--KSPAYQQTGLISHSNAEGLLLLEQVISGAYGPILPAI---------------------------V
DT---SRPETWLEYP-RVMAVSQSHTEYVAVS----------------------PINEGD-----LTTVVEGWLMNLLAAELRMSRLRRDKEFQIYGVDS
IILAQLVSKIDHFETIHLDPSVFLEYPTIAGMSAYLLDN-----------
>tr|F5B9D5|F5B9D5_9SPHI Polyketide synthase OS=Chitinophaga sancti GN=elaO PE=4 SV=1
---VHKTWQEQGTNE--QRAFHGKVLVLATKPQYNNIDI---------IDVNSLPLADGTA--------------GL--------------------IDL
G------C-DDTAE-QALAGIPLLQQLISGNR--PLT-MIGATQGLEGRKASGQTGALRAGLFRMLQAEYRYLNAIHLDIEHDGN------AAQILSELS
V---APEICFRDGKRYRAVLTASTPK-TN---MPAFPSGGVLLVTGGTRGIGLECARYFIKKYGVKLVLTGR---EPLPPEKLKAIQALRA----EGVTV
LVRSVVLNDETAVNALLTEIRTTLG-DISGVLHCAGMVDNPAFIRKSVHSIREVLVPKVTGLQTLFQSLSKDPLQFFVLFSSVAGTVPTAGQSDYAMANA
YMDYFAAAA--QASFPVVSIQWPSWKETGFGEV--KSPAYQQTGLISHSNADGLLLLEQVISGAYGPVLPAM---------------------------V
DT---SRPETWLEYP-KVVTEPL-PAAPVAVP----------------------SMNKDD-----LTTVVETWLMTLLAAELRMGRLRRDKEFQIYGVDS
IILAQLVSKIDRFETIHLDPSVFLEYPTIAGMGAYLLDT-----------
>tr|A0A0K6M1G8|A0A0K6M1G8_BACAM Polyketide synthase PksJ OS=Bacillus amyloliquefaciens GN=pksJ_8 PE=4 SV=1
---LTKQWEPSPLELRE--PCPRSVAILTGGDHMPNHRITS---------------------------------DGV--------------------IDL
G------AAKEEAS-GDMPGIKWLQQLIEGHK-EGIT-LLCVTKDLEGKKANQITGAKRAGLYRMLACEYSHLSSRHLDLEGALS------AKQIADEFH
A---RAEVCRRDGLRYRAVLSGSENT-QE---RIDFPDHHVLLITGGTRGIGLLCARHFAEHYGVKLVLTGR---ETLPPRKIEAVLDLES----KGVQV
KVLSVPLADEAGLRQELSQIKQMLG-PIGGVIHCAGVTDTLAFIRKTDEDIQRVLEPKVEGLQALYSVLSEEPLKFFVLFSSVSAAIPAAGQADYAMANA
YMDYFADSY--KEQLPIVSIQWPNWKETGMGEV--TNKAYKESGLYSITNAEGLQLLDGILLESARGVLPAV---------------------------L
NP---KLPERFLRRS-QD--QPMSAMVKSAEKTA------------------DTAADNAQ-----LTRKTEEWLKELFSEELRIDQLETDVLFQDYGVDS
IILAQLLQRINRNLSASLDPSILYEYPTIQSFAKWLLEG-----------
>tr|I4CJP0|I4CJP0_9NOSO Polyketide synthase OS=Nostoc sp. 'Peltigera membranacea cyanobiont' PE=4 SV=1
---LVPQWQRQALPKDAQVVLQGTIIVLASDDQHHHAAFVENLGQNKVPDVKSHTYTQITPQHYQFCFDNADRARGI--------------------LDL
A------N----SQ-CILGNIALLQS-LLTRK--PLR-LLQVTQGLQNGTSTNLSGAELTGLFKMLGAEYNSCYAKTIDLDPNNS------LSQIAQEYQ
D---YTEICHRDGDRFVSTLAHLNSK-PQ---SQKL-PQGIVVITGGTGGIGNEVAQHLA-RQGYTLVLMGK---TTLPPRKITNILNLEK----QGVTV
ELYTGELTDYAALEVYFQNIRRQYG-QITQVFHCAGCVSSPAFLHKTLDSIVSVLSPKTTALEVLHRIFEHDNLEAFVLFSSLSSVVPKVGISDYATANA
YMNYFATYQVAQGNTYYRAIQWSNWKEVGMGQL--TSQPMTKIGLVPLSTAVGLQSLDTILALPPQITVACL---------------------------A
SQ---EQVSE-LSLV-K---EQTTKIQPVSLPKQ------------------NFPTDSNA-----LQTYVLESLSQILSRELHIDQIKYETSFEALGVDS
IFLAGIVNKIDQWLGMRLDPSLLLQYDSISRLAEHLISH-----------
>tr|G8M267|G8M267_CLOCD Putative polyketide synthase component,beta-ketoacyl synthase family protein,phosphopantetheine-containing protein OS=Clostridi
------------------------LILKDENGKGEILQILKEYGRKVKTVSIGEEYKKLDDDNYIARN-KEDDFVTVLNDVEWNGR--IQIVHMLSLGVN
C-ENGIEGVDKKIESGVISLYYLTRAIMKSSKEVELSLISNCVSDVTGSHEIVPENAALFGLGRAIRNEISLIKCRCIDIDEQ------TELFNIAMDLI
INGDFYETAYRNGKRYVQKFDSLDIKDCPD-KRVEIKSEGVYIITGGLGGIALAVAKSLALKNKVNIALISRSKIPEREKGTDNRIIAIK-EIEELGSKV
TCFSADVKDIDKVSVIVEKLRQDFG-KINGIIHSAGIPGDNFVVQKEEKAFREVLSPKIHGTWILDKLTEKDDLDFLILFSSVASVLPAPGQGDYAAANA
YLDSFAAYRE-NLGKRTLVVNWVAWKETGMAYDTGTNID---TAFKALYTDKAIDALFTVLNKGVQRVLIGLNYDD----------------KMIYLKYP
----LKISERIK--------SAIGIQSS---------KEKDNKVNKKKDAAVV--ELRG--RSDNDYTETEKLIGQIWSEALGYTQIDINDNFIELGGDS
IMAMNLVTQIAKATGVKLNISEVLSYMTIYELAKYMDEK-----------
>tr|U4R6E3|U4R6E3_9FIRM Beta-ketoacyl synthase (Fragment) OS=[Clostridium] papyrosolvens C7 GN=L323_03260 PE=4 SV=1
------------------------VYFKIRSGDDEVLKILKQRQNSVIEVDVGTVYHRVSEYRYTVGI-GEEDFAKLISDTIGYKI--TQILYLSELTSD
C-GEKINQTVGNPSQSIYTMFYLTRALVNSKGALDVVLISGYANKVTGKEEIIPQNTALFGYGKVVGQEYPDIKVRCIDVDDN------MTAKELVPEIS
SGNKNFLVSYRNGKRYVEIFESIAASEIPQ-NDLVLNKKGVYIITGGIGGIGLEIAKYLASKENINLVLLSRSELPERDKDKNKKIKSIL-EIESTGSNI
AYYRADVTNYEEVSAVINQLRTQYT-KINGIIHSAGVPGAGLIITKNEDQISKVLASKIIGTYNLDRATENDELEFFVLFSSIKSLLGGEGQSDYAAANA
YLDAYTHYRN-RLGKRTLTINWPAWKETGMAADYGVNKD---NVFKAISTQDGIEAFGKALLSDMERVIIGLDYSD----------------SILSSNFK
----LKIEQELK--------KSVSGRN----------------SRAKEQIHSF--VLKG--KEGETYTEIEKIVGKIWIEALGLDEINIYDDFYGMGGDS
ILAINIVSGIKNLMNLDINISDFFDNPSVYDFAKFIEAT-----------
>tr|K0UP11|K0UP11_MYCFO Polyketide synthase (Fragment) OS=Mycobacterium fortuitum subsp. fortuitum DSM 46621 GN=MFORT_24202 PE=4 SV=1
------------------------------------------------------------------LPTTDAAAGQLENELRTAAASTLHILDIAAVDGE
PTASSMRTLLRMQHQILAGTRRLFRAAADAGVKATIWLVTRGAQHVADADTVAPEQSALWGFGRAAALELPQLWGGLADLSEG----TTDEWTAVLNRVT
TGRREDQIAVRDQAVYVPRLVRREDPNGT---PLELRSGATYLVTGGLGSIGLEIAGHLAAHGARHLVLTSRRDPSEAAA------QRIAALSDQHGCDI
RAVTADVADAHDVARLLSTVAA--EMPLAGIVHAAGELGTTPLSELDDAEVDRVFAGKVWGAWHLSEAAAEQKLDFFITTSSIASVWGGYGQTAYGAANA
FLDGLAWRLR-EQKIPGTSVNFGPWA-TGMA-DAESRARLDQRGVRTLAPADALAGLADAVAVPAQGVVARIDWSRFL----------------------
---------PLYQQA---------GRRGFLAELETEAPAEPTTASGKTQLVERLTNA--------PVQQRKKYLRDSVAEVTRVDEIREDAGFFDLGMDS
LMAVELRRRIEQGVGAEIPITLVMDHPRISDVSEYLLGD-----------
>tr|X5KZ47|X5KZ47_9MYCO Polyketide synthase OS=Mycobacterium mageritense GN=BN978_03415 PE=4 SV=1
------------------------------------------------------------------LPASDADEAQLADALRTAAASTLRILHVAALDTE
G-APSMRSLLRMQHHVLAGTRRLFRATAAAELRAPTWLITRGAQHVTDADTVAPEQSALWGFGRAAALELPQVWGGLADLTDA----GADAWAGLLDRVA
AATREDQIALRGHEVYVPRLVRREEPSGA---SLELRDDATYLVTGGLGSIGLEIAAYLAAHGAKHVVLTSRREPSDAAA------QRIEALREQHGTDI
RAVTADVADAHDVARLLAGVRA--DMPLAGIVHAAGEIGTTPLGELDSAEVDRVFAGKVWGAWNLSEAAADLKLDFFINTSSIASVWGGFGQTAYSAANA
FLDGLAWHLR-EQGVAGVSVNFGPWS-TGMA-DAESRRRLEQRGIRTLSPADALAGLADVVTARAQGVVARIDWARFL----------------------
---------PLYQQA---------GRRGFLTELEREVPQSAATASGKTELVERLTNA--------PVQQRKKYLRDAVADVTRVDEIREDAGFFDLGMDS
LMAVELRRRLEQGVGHEIPVTLVMDHPRLSDAADYLLGD-----------
>tr|H8IQE5|H8IQE5_MYCIA Beta-ketoacyl synthase OS=Mycobacterium intracellulare (strain ATCC 13950 / DSM 43223 / JCM 6384 / NCTC 13025 / 3600) GN=OCU_18
------------------------------------------------------------------LPASDADEERLAETLRAAATATLRIVHVAALEAG
A-TPSMRSLLRMQHRILGGTRRVFRAAVAAELRGPIWIVTRGAQRVADTDTVAPHQSCLWGFGRAASLELPHVWGGLADLSEGGD-NAADEWSALVDRIA
AAVREDQLALRDRAVYTPRLARRSAPSGT---PLHLRGDATYLVTGGLGAIGLEIAGHLAANGARHLVLTSRRDPSDATQ------QRINALGEQHGCQI
RVVAADVADAHDVARLLASVQA--ELPLAGIVHAAGEIGTTPLSALQDAEIDRVFAGKVWGAWHLSEAAADLDLDFFISTSSIASVWGGFGQTAYGAANA
FLDALAWRLR-GQGIFAVSVNFGPWS-AGMA-DAESRARLDQRGVRTLSPADALAGLADAVAALVQGVVARIDWARFL----------------------
---------PLYQQA---------GRRAFLAELEREVPGLAGIVAGKTPLVERLTGA--------PVQQRKKYLRDAVAEVTRVDEIREDAGFFDLGMDS
LMAVELRRRIEQGVGKEIPATLAMDHPRLSDVADYLLRD-----------
>tr|A0A0J6VSH4|A0A0J6VSH4_9MYCO Erythronolide synthase, modules 3 and 4 OS=Mycobacterium chubuense GN=eryA_3 PE=4 SV=1
------------------------------------------------------------------LPLSDAEEADVADAVRSAAAPALRIVHIAGLDAD
A-STSTRSLLRMQHRALPGTRRLFRAAATAEVRSPIWLVTRGAQRVADGDVTAPEQACLWGFGRAAALEAPQLWGGLADLAAG----TAEEWSALVQRIA
TGIRDDQIALRGHDGYVPRLIRRTGPNAQ---GPQIRSEATYLVTGGLGAIGLEIAGHLAAHGARHLVLTSRREPGEAAR------QRIAALAEQHGCEV
RVVAADVADAHDVARLLAMMHA--ELPLVGVVHAAGEIGTTPMTDLTDDEIDRVFAGKVWGAWHLAEAAAELNLDFFVSTSSIASVWGGFGQTAYGAANA
FLDGLSWRLR-ERGVAGSAVNFGPWA-VGMA-DARSRARLEERGVATLSPADALAGLADAMATAPQSVVARIDWARFL----------------------
---------PLYEQT---------GRRGLLAELNQELPQA--TASGRTALVERLTEA--------PVQQRRTYLRDAVAEVTRVDEIREDAGFFDIGMDS
LMAVELRRRIETGVGRDIPATLAMDHPRLLDVADYLLGE-----------
>tr|L8FL03|L8FL03_MYCSM Malonyl CoA-acyl carrier protein transacylase OS=Mycobacterium smegmatis MKD8 GN=D806_0401 PE=4 SV=1
------------------------------------------------------------------LPGSDADEAQLVDTLRAASAGELYVVHIAAGDGD
--ASPMRDLLRVQHRTLGGLRRVFRAANDAELRSPIWLVTRDGQRVTDTDTVAPDQSCLWGFCRAAALELPHLWGGLADLSG-----ADTEWPQLIARIT
A--GEDQIALRGDTVYAPRLVRRTGPSEA---PLPVREDRTYLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPGDDAR------RRLDGLREQCACDV
RVITADVADAHDVARLMTTVAA--ELPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLDLDFFVSTSSIASVWGGYGQTAYGAANA
FLDGLAWRLR-ERGVTAVSVNFGPWA-AGMA-DAESRARLEQRGVRTLSPAEALAGMADVVAGPVQGVVAKIDWSRFL----------------------
---------PLYQQA---------GRRAFLSELEGELPAATATAPGKPPLVEQLTKA--------PVQQRKRYLRNAVAEVTRVDEIREDAGFFDLGMDS
LMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVE-----------
>tr|K0UC12|K0UC12_MYCVA Beta-ketoacyl synthase (Fragment) OS=Mycobacterium vaccae ATCC 25954 GN=MVAC_27309 PE=4 SV=1
------------------------------------------------------------------LPMSEADEIKLADALRAAATPELRILHVAALDSD
T-APSMRSLLRMQHRILGGTRRLFRAAAAAQLRTPIWLVTRGAQRVVDSDTVAPDQSALWGFGRAAALELPHLWGGLVDLAG-C---TTEEWTGLLDRLA
AAVREDQMALRDRTVYVPRLVRRTGPNLT---PLQLRSDATYLVTGGLGAIGLEIAGHLAAHGARHLVLTSRRAPGQAAQ------QRIDALREQHSCEI
RVSATDVADAHAVARLLAEVAA--ELPLAGIVHAAGEIGTTALAEVDDAEVDRVFAGKVWGAWHLSEAAAELPLDFFISTSSIASVWGGYGQSSYGAANA
FLDGMCWRLR-ELGIQGFSVNFGPWS-AGMA-DAQSRDRLAQRGIRTLSPADALAGLADATTSTAQTVVARIDWARFL----------------------
---------PLYQQT---------GRRGLLAELDREVPDT--TPSGTTPLVDRLTEA--------PVQQRRKYLRDAVAEITRVDEIREDAGFFDLGMDS
LMAVELRRRIEQGVGKEIPATLAMDHPRLSDVADYLLGE-----------
>tr|A0A024QIT6|A0A024QIT6_MYCNE Beta-ketoacyl synthase OS=Mycobacterium neoaurum GN=BN1047_00306 PE=4 SV=1
------------------------------------------------------------------LPVSDADEQRLVTDLAAAVQPDVRILHVAALDSH
T-TPSMQTLLRMQHRVLDGTQRLFRAAATAGVRAPIWTVSRQAQRVAEVDKVAPEQTLLWGFGRAVALEYPQVWGGLADVSGD-----AQEWAELVRQIP
GPRGEDQIVLRGRQVWVPRLVRRTGPNPK---PLELRSEATYLITGGLGSLGLEIAAHLAAHGARQLVLTSRRSPNEAAQ------KRIADITATHGCAV
RVMTADVANPHDIAHLIATVRA--ELALAGIVHAAGENSTTPLATLEAAELDRVFGGKVWGAWYLSEAVEGLPLDFFVSTSSISSVWGSYGQSAYGAANA
FLDGLTWRLR-EQGIAGYSVNFGPWA-AGMA-DPQARAQLERRGVRTLPPADALAGLADVLVG---SVLARVDWSKFL----------------------
---------PVYLQT---------GSRALLAEVAREVPES--QASGATPLVGQLSTA--------PVQQRKKYLRNAVAEVTQVDDIREEAGFFDLGMDS
LMAVELRRRLEGAVGQELPATLAMDYPRLSDVADYLLGD-----------
>tr|L0IPH7|L0IPH7_MYCSM Polyketide synthase family protein OS=Mycobacterium smegmatis JS623 GN=Mycsm_00206 PE=4 SV=1
------------------------------------------------------------------LPASDADGEKLADALHAAALSTLRIVHVAALDSS
T-APSMRSLLRMQHRILGGTRRLFRAAAAAELRRPIWVVTRSAQRATESDTVAPDQSCLWGFGRAASLELPHVWGGLADLSEG----TTEEWSRLINRIT
MEVIEDLIAVRGQAVYVPRLVRRDDLTGT---QLKVRSNATYLVTGGLGAIGLEIAGYLAAHGAQHLVLTSRGAPSEAAQ------QRIDSLAEQYDCEI
RVITADVGDAHGVARLLASVRA--ELPLTGIVHAAGEIGTTPLSDLDDAELDRVFAGKVWGAWHLSEAAADLQLDFFICTSSIASVWGGFGQTAYGAANA
FLDGLAWRLR-EQGISGVSVNFGPWS-VGMA-DAESRARLDQRGVATLSPADALAGMANVVTASEQGVVARIDWARFL----------------------
---------PLYQQA---------GRRAFLAELEREVPTQATASGKKTQLVERLASA--------PVQQRKRYLRDAVAEVTRVDEIREDAGFFDLGMDS
LMAVELRRRLEQAVGREIPVTLVMDHPRLSDAADYLLGE-----------
>tr|A0A024K197|A0A024K197_9MYCO Beta-ketoacyl synthase OS=Mycobacterium triplex GN=BN973_04061 PE=4 SV=1
------------------------------------------------------------------LPASDADEEQLAEALRAAAVSTLRIVHVAAVDAE
R-TPSMQSLLRMQHRILDGTRRLFRAAVAADLRAPIWLVTRGAQRVTDTDTVAPDQSCLWGFGRAASLEHPRLWGGLADLAEG----TADEWARFVDRIS
AAPREDQVALRDQSVYVPRLVRRSGPSVT---PLQLRTDATYLVTGGLGSVGLEIAGYLAAHGAGNLVLTSRRAPSEAVQ------QRVDALAAQHGCDV
RVFAADVADAHDVARLLARVRA--ELPLAGIVHAAGEIGTTALGNLDQAEVDRVFAGKVWGAWHLSEAAADLQLDFFLSTSSIASVWGGYGQTAYGAANA
FLDGLSWRLR-ERGVCGASVNFGPWA-AGMA-DAESRAKLDQRGIRTLSPADALAGLADVAASSAHGVVARVDWARFL----------------------
---------PLYQQA---------GRRAFLTELAHEVPDA-VTPSGKTQLVERLTNA--------PLQQRKKYLRDAVAEVTRVDEIREDAGFFDLGMDS
LMAVEMRRRIEHGVGKEIPVTMVMDHPRLSDVADYLLGE-----------
>tr|A0A064CKI8|A0A064CKI8_9MYCO Polyketide synthase OS=Mycobacterium aromaticivorans JS19b1 = JCM 16368 GN=Y900_014900 PE=4 SV=1
------------------------------------------------------------------LPVSDADEERLVAELTAAVQPALRILHLAALDSD
G-SSSMRSLLRMQHRVLGGTQRLVRAAAAAELRSPIWVLTHNAQRVSDADTVAPEQSGLWGFCRVAALEYPQLWGGLADVSGT----GADEWTRLIKQVV
TSPGEDQIALRDSGVHVPRLVRRTGPNST---PLELRSDATYLVTGGLGSIGLEIAGYLAAHGARQLVLTSRRASDEAAQ------RRIDALSEQHGCAV
RVVAADVADPHDVARLLATVAA--ELPLAGIVHAAGENSTTPLSSLDSTEIDRVFSGKVWGAWYLSEAAADLNLDFFLSTSSISSVWGSYGQSAYSAANA
FLDGLTWRLR-ERGVHGISVNFGPWS-AGMA-DQDARTQLDRRGIRTLSPTDALAGLADIMAAPAEAVVARMDWARFL----------------------
---------PIYLQA---------GRRSLMAEVAREVPES--GASGTTRLVEQLTAA--------PVQQRKKYLRNTVAEVTRVDEVREEAGFFDLGMDS
LMAVELRRRLEQAVGKELPATLAMDFPRLTDVADYLLGE-----------
>tr|A0A0Q8ZKV9|A0A0Q8ZKV9_9MYCO Polyketide synthase OS=Mycobacterium sp. Root265 GN=ASE48_14055 PE=4 SV=1
------------------------------------------------------------------LPASDADEERLAADLRAAVEPTLRILHVAALEKD
N-APSMRTLLRMQHRVLDGTQRLFRAAAAADLRAPIWVVTRGAQRVLDTDPVSPEQTSLWGFCRAVALEYPQVWGGLADVSGV-----AEEWSRLIGQIV
GGRGEDQIALRGQLIHVPRLSRRTGPNPT---ALELRSDATYLVTGGLGSLGLEIAGYLAAHGARHLVLTSRRAPSTAAQ------QRMDALRQQYGCEV
RAVASDVANPHDIAHLMATIAA--ELPLAGIVHAAGENSTTPLSTLDPAELDRVFSGKVWGAWYLSEAITDLQLDFFLSTSSISSVWGSYGQSAYSAANA
FLDGLTWRLR-EQGVPGFSVNFGPWS-AGMA-DGEARAQLDKRGVRTLSPVDALAGMADVMVG---GVVARIDWARFL----------------------
---------PIYLQA---------GQRALLAEVAGEVPET--GSVGTTRLVERLTSA--------PIQQRKKELRDAVAEVTQIDEIREETGLFDLGLDS
LMAVELRRRLEQSVGAELPATLAMDHPRLTDMADYLLGD-----------
>tr|E6TLP1|E6TLP1_MYCSR Polyketide synthase family protein OS=Mycobacterium gilvum (strain DSM 45189 / LMG 24558 / Spyr1) GN=Mspyr1_03500 PE=4 SV=1
------------------------------------------------------------------LPKSGAEEHELADTLRDAAATDLRIVHVAALDAA
E-DTSMKSLLRMQHRVLGGTRRLFGAAVAAQLRSPMWLVTRGAQHVTDTDVVAPDQTCLWGFGRAASLEHPQIWGGLADLGGG----TSDEWSRLLNRIA
AAVMEDQVAVRGSTSYVPRLVHRDTPSGK---PLHLRADATYLVTGGLGSLGLEIAGYLAANGAGHLVLTSRRTPDEAAA------SRIEALRERHGCEV
RVVTADVADAHAVARLLATVQA--EMPLAGIVHAAGEIGTTPLADLDDAEVDRVFAGKVWGAWHLSEATSDLQLDFFISTSSIASVWGGFGQAAYGAANA
FLDGLAWRLR-EQGVAGVSVNFGPWS-AGMA-DAQSRARLEQRGIKTLSPADALAGLSDAVIS-PHPVVARVDWSRFL----------------------
---------PLYQQA---------GRRGFLAELERELPAAQGTASGRTPLVERLTTA--------PLQQRKRYLRDAVAEVTRVDEIREDAGFFDLGMDS
LMAVELRRRIETGVGKEIPVTLVMDHPRLSDAADYLLGD-----------
>tr|X7UNV1|X7UNV1_9MYCO Malonyl CoA-acyl carrier protein transacylase OS=Mycobacterium sp. MAC_080597_8934 GN=L841_4391 PE=4 SV=1
------------------------------------------------------------------LPASDADEERLEIVLRAAAAAPLRIALVAALDSG
T-APSMRSLLRMQHRVLAGTRRLFRAAAAAELRQPIWLVTRGAQRVTDADTVFPDQSCLWGFGRAASLEYPQLWGGLADLAQD----SAEEWSRLVRVAS
AAVGEDQIALRGSDIYVPRLTRRSGPAAA---ALTLRADATYLVTGGLGSIGLEIAGHLAAQGARHLVLTGRRAPGEAAQ------RRIDALSQQHGCEV
RVIAADVADAHHVARLLGAMRA--ELPVAGIVHAAGEIGTTPLSDLEDAEIDRVFAGKVWGAWHLSEAAADLRLDFFISTSSIASVWGGLGQTAYGAANA
FLDGLAWRLR-EQGVNGISVNFGPWS-AGMA-DENARARLAQRGIKTLSPADALAGLTDVMATAAQGVVARIDWTRFL----------------------
---------PLYQQA---------GQRSLLAELAREVPDF-ATPSGKTGLVERLAGA--------PVQQRRKFLRNAVAEVTRVDEIREDAGFFDLGMDS
LMAIELRRHIEQGVGKQIPATLAMDYPRLSDVAEYLLGD-----------
>tr|J4JVU2|J4JVU2_9MYCO Tylactone synthase modules 4 & 5 OS=Mycobacterium colombiense CECT 3035 GN=MCOL_V205565 PE=4 SV=1
------------------------------------------------------------------LPASDADEERLEAALRAAVAPALRIVHFAALESD
T-APSMRSLLRMQHRVLGGTRRLFRAAAAAELRAPIWLLTRDAQRITGADTVSPVQSCLWGFGRAAALEHPQVWGGLADLHDG----SADEWSRLINVVA
AATREDQVALRDQAVYVPRLTRRVGPLAT---PLVLRGDATYLVTGGLGSVGLEIAGYLAGHGARHLVLTSRRAPGDAAQ------RRIDALSERYGSEF
RVIAADVADPHDVARLLATVQA--ELPLAGIVHAAGEIGTTPLSELGDAEVDRVFAGKVWGAWHLSEATADMRLDFFLSTSSIAAVWGSFGQTAYSAANA
FLDGLADRLR-EQKY--ISVNFGPWS-AGMA-DEDARARLDQRGVRTLPPADALAGMADLMVAISQGVVARIDWSRFL----------------------
---------PLYQLS---------GKRSFLAELEPEVPAS--APSGTTRLVERLTVA--------PVQQRKKYLRDVVAEVTRIDEIREDAGFFDLGMDS
LMAVEMRRRVEHAVGSELPATLAMDYPRLVDVADYLLGD-----------
>tr|B1MJ75|B1MJ75_MYCA9 Probable polyketide synthase OS=Mycobacterium abscessus (strain ATCC 19977 / DSM 44196 / CIP 104536 / JCM 13569 / NCTC 13031 / 
------------------------------------------------------------------LPVSDADEAELVEALRSAADSALRIVHVAALAGQ
G-SSSAQSLLRIQHQVLGGTRRLFRAAAAAELRAPIWIVTRGAQHVIEGDTVAPEQSALWGFGRAAALELPQVWGGLADLSDA----GTDEWAQFIGRVS
VSTREDQLALRGQAVHVPRLVRREEPSGK---PLEVRSDATYLVTGGLGSIGLEIAGYLAGRGAKHLVLTSRREPGEAAR------QRIDALAA-QGCEV
RAVTADVADGHDVARLLAGIQA--ELPLAGIVHAAGEIGTTPLSDLEDAEVDRVFAGKVWGAWHLSEAAAGLKLDFFINTSSIAAVWGGYGQTAYSAANA
FLDGLAWRLR-EQGIAGTSVNFGPWS-AGMA-DAESRARLEQRGIKTLSPTDALAGLADVVAAAVQGVIARIDWARFL----------------------
---------PLYQQA---------GKRGFLAELDREVPSHVAAQSGSTQLVERLANA--------PVQQRKKYLRDAVAEVTRVDEIREDAGFFDLGMDS
LMAVELRRRMEQGVGKEIPVTLVMDHPRISDVADYLLGD-----------
>tr|A0A0R3IE22|A0A0R3IE22_9MYCO Polyketide synthase OS=Mycobacterium sp. H070 GN=AOT89_12920 PE=4 SV=1
------------------------------------------------------------------LPTSDADEQQLADAFRSAVSSALRIVHVAALDG-
G-TSSARSLLRIQHQILGGTRRLFRAAAAAELRAPIWVITRGAQRITETDTVAPEQSALWGFGRAAALELPQVWGGLADLADA----SAAEWSQFISRAS
AAAREDQIALRDQSVYVPRLVRRENPSGT---PLEIRDNGTYLVTGGLGSIGLEIAGYLAACGAKNLVLTSRREPNEAAQ------QRIDALGAQHGCEV
RVVTADVADAHDVARLLAGVQA--ELPLAGIVHAAGEIGTTPLSDLDDTEVDRVFAGKVWGAWHLSEAAADLKLDFFISTSSIASVWGGFGQTAYSAANA
FLDGLAWRLR-EQGVAGTSVNFGPWT-AGMA-DAESRARLEQRGIKTLSPSDALAGLADVVAAGAQGVVARIDWARFL----------------------
---------PLYQQA---------GRRAFLAELEREVPSHSQAQSGTTQLVERLAGA--------PVQQRKKYLRDAVAEVTRVDEIREDAGFFDLGMDS
LMAVELRQRMEQGVGKEIPVTLVMDHPRISDVADYLLGE-----------
>tr|I4HRS0|I4HRS0_MICAE McyD protein OS=Microcystis aeruginosa PCC 9809 GN=mcyD PE=4 SV=1
------------------------------------------------------------------FPQGDLAGAKLMNQLVATTIYPLRILEIGGLDIE
KSSEQLPSLLSILRKIIHCQRFLFQALLQQENPPALILVTQGAVPAKAITLTSPSQASLLGIAFSLVLEHPELNFKAIDLDPDEV-NSAD---KLLQEIY
-NPQENRVALRGEQRFYPRLVQRKLD--G---NINFSPDGYYLITGGTGGLGLATTRWMIEKGARNLVLCSRRGAEGVSP------E-ILANLSSSGAEI
TLKKLDITDAEKLHTVLEECRS---KPVRGVFHIAGTLDDTTLLRLTPERFNYVLAPKVKGTWLLHQLTLNDPLEFFVCYTSAVSLIGSAGQANAAAANA
FEDAFIYYRQ-AHHLPGTVINWGPWSEIGAAVDRNVLERLAAKGYAAMKPDLALNALEKILLNIIRAGVIKIDWQQFP----------------------
---------YIHQSF----------YKNFLP-------QG--QAAPSSEFLKQWQNL--------TLKERPNHIIMRVST-GRSNTFSPQQGFFDLGMDS
LTSTELRNLLQTDFNCSLPSTITFRFPNVEALANYLQQE-----------
>tr|A1U9G3|A1U9G3_MYCSK Beta-ketoacyl synthase OS=Mycobacterium sp. (strain KMS) GN=Mkms_0254 PE=4 SV=1
------------------------------------------------------------------SPVSDADEASLADALRASVDGAVRILHIAALDAT
T-APSMRTLLSMQHRILGRTRRLFHAVTTTGLRTPIWLITRGAQRVTATDTVAPDQSALWGFGRAASLELPHLWGGLADLPTGPG-ASEDEWSRLLDRIA
ADVTEDQVALRDGAVHVPRLVRRTGPSGA---PLRLRSDATYLVTGGLGAIGLEIAGYLAAHGAGNIVLTSRRAPGDAAQ------QRIDALRDKFGCAI
RVATADVADAHDVARLLAGVQA--ELPLAGIVHAAGEIGTTALSAMDQAEVDRVFAGKVWGAWHLSEAAVDLQLDFFISTSSIASVWGGFGQTAYGAANA
FLDGLAWRLR-EQGIAATSVNFGPWS-AGMA-DAESRARLEQRGVRTLDPADALAGLADVVAGATQGVIARIDWARFL----------------------
---------PLYQQA---------GRRAFLTELEREAPVAAATASGKTPLVERLSGA--------PVQQRKKYLRDAVAEVTRVDEIREDAGFFDLGMDS
LMAVELRRRLEQGVGKEIPVTLVMDHPRLSDAADYLLGE-----------
>tr|E1VID6|E1VID6_9GAMM Erythronolide synthase, modules 3 and 4 OS=gamma proteobacterium HdN1 GN=eryA PE=4 SV=1
------------------------------------------------------------------DGMSDADAIKS--AVLPLQEKVLPVLLT------
--APVMPSDLSVLEPVLEAVRAL-VVGGDSTNPVRLWVVSEGAYGTAYGANINLSAWPLLGFAKGLALETGELWGGILDVSGTAG-EQAA---AILAELA
GQAIEDVVKYEGNVRSVQRLQA-DRAQAT---LPSLDGKASYLVTGGLGGLGLYVAQALALSGAKNLVLMSRRGDLQSLQGE--PRDRVEAL-QKNGVNI
RVVNVDVADASAVSNLIQRLAN--GEPLKGIVHCAGVNDIVLAQDMQRDQWRNVTRSKVQGGWNLHQASLSLPLDFFVMFSSIASVWGSGGMAHYAAANH
FLDGLVDYRL-ALGLPAAAFNWGPWGGAGMA-TGDAAEEAARRGLRPFDPQSGIELLSKS---KAHQIMADVRWDRFR----------------------
---------EIMEMR---------RAHPFFGALGRTLSATT---GEKSAFFKSLYPL--------VPTERAEYLQGLLGRVGKAETVDSEMPLMDLGIDS
IMALEIKKQLEADTGQAMRATLIFDYPTINKIAEHFSVA-----------
>tr|A0A085WVX4|A0A085WVX4_9DELT Malonyl CoA-acyl carrier protein transacylase OS=Hyalangium minutum GN=DB31_0098 PE=4 SV=1
---FKPEWFPSALAPSVPATAGAVLVFDPDGSFTQQVDRLRGSARAVVRIQPGAEFRRVGPRHYELQPEHAADYERLLDALANDGLRLAGILFFWGKRSR
FESPDAEGLDDALGQGLYPLVRLIQALLPRRKDERIQLLYVYRSGGEEVIAHH---EALSGLARAVTAAAPWLNFRLLGMDASGTTPERVLAELHASEAA
T---QVEVRYRNGERHVRGVRPVPAHEAAAAMGPAFRQGGIYLITGGLGGVGYELAKYLAGKYRARLVLTGRSPL---EDELRRKLSHLEG----LGSDA
VYVQADVVSRKDVDHCLAYVKA-RYSGLHGIIHCAGLLKEATLADKRQEDFGTTLAPKVQGTLVLDQATRAAPLELFVVLSSVSTVIGTSLAADYATANR
FLDSFAALRE-SRGQGQTSICYPYWRDGGMRMSPEKELVLQATGMEPLSSAQGIQALETALAL--------------GHQQGL---------PQILTAFG
------ELEKMQRALQAAPPP-------P--------AAAAATPPARPATP-----------PDASQAALEARVELAVKTLRLQGTVNPRSELSGYGFES
ITILEFTQALNARYGTALSPALFYEHRTIEGYV-----------------
>tr|A0A074L6W7|A0A074L6W7_PAEPO Uncharacterized protein OS=Paenibacillus polymyxa GN=EL23_24325 PE=4 SV=1
----------------------QVIVFGTDTGLWNSLKK---RGIKAVLVQPGDAYRSVQGDIYEIDPLNPKHYEMLFSTIKQNQQTAEALIYAWSD--Q
RFVSEKEELQTELERGIYSLFYLSKALMRESLRCKLLYVYQG-----SGQ---PQNAAVSGFARTLRKENPALIYATVELSESAETSLDQL----LSEFS
VDDEEVEIRYQQFVRYMSLINELGTS------SISLREKGTYMITGGLGGLGSIFAGYLASKYKARLVIAGRSP---LTSEHEQKI----KQWERCGASV
LYVQADISLREQCIAMIAKAKE-RFGHIHGVIHAAGVLRDAYILRKSIDQIEEVLAAKLYGTVWLDEATRHEELDFFLMFSSIMSVIGNAGQCDYAYANA
FMDYYAHHRTEGRSGKSLLINWPLWKEGGMTVDAPLAFMENTMGILPISTEEGIRAFEDALH-------MSGD------QMIVLK--E-NPSKKI-----
---------KLFNST-SSIKEKFSAKG--------QLSES-----DEQMIYR------G----------LCEDIRMITSDILDKDTIEMDTDYSEYGFDS
ISTTDFINRVNQKFHLELTPPVFYEFVNMGSFVSYLK-------------
>tr|B6VN93|B6VN93_PHOAA Syringomycin synthetase OS=Photorhabdus asymbiotica subsp. asymbiotica (strain ATCC 43949 / 3105-77) GN=syrE PE=4 SV=1
-WCRHPRWLPKPLDEAK-QNRAPWLIFGAQ---AAELSDLWEAAAGSIVVEDADEFQQQGTYRFSLRKDQLEDYQQLIDCLIQQQLLPERIIWCWTAAVV
PQPEAAEQLAAAI-----------KALTGHHRVFDITLISRGAARVL----EACHAAPALGLLGILAAEYPGCSARHIDLDDNTFATHQSLIAELYDEAT
EGMPVTSIMLTQGKRELQTFAELDIPHRQ-----ILRDGGVYLITGGLGGIGQLLARYISNKCSAKLGILSRRETHPANEA-------FLDALRKSGAEV
IILRADVADGVALTEALAQMRARFG-AINGVIHSAGIEASGLLEHSTSQDWRHVMAAKISGTQQLMTAIRQDSDFVLLC-SSLASLIGGIGQADYAAANR
YLDAVAHYWR-QQAIPVTSVNWDTWAEVGMAVNYAARRKE---------SVIGL----------------------------------SNQEGCAIFDLA
ITG-----------MET--QVVVSKFTPVRRTQSRNLSA--------------IA------D----SASPEEAVRQLWYELLGEETINLEDDFFELGGHS
LLATQMISRLRDHFQHCLTLAEFLEQPTMARVV-----------------
>tr|A0A0J9F9X7|A0A0J9F9X7_PHOLU Uncharacterized protein OS=Photorhabdus luminescens subsp. luminescens GN=TI10_04685 PE=4 SV=1
-WCRHPRWLPKPLGETK-QNRAPWLIFGAQ---AAELSDLWEAAAGSIIVEDADEFLQQDTYRFSLRKDQPEDYQRLIDCLIQQQALPERIIWCWTAAVI
SQPEAAEQLAAAI-----------KALTGHHRVFNITLISRGAARVL----EACNAAPALGLLGILAAEYPGCSARHIDLDDDTFATYQSLIAELYEETT
EGIPVTSITLKQGERELQTFTEFDIPHRQ-----ILRDGGVYLITGGLGGIGQLLARHISNKCNVKLGILSRRETNATSEA-------LLDVLRKSGAEI
MMLSADVADGAALTKALAQMRARFG-AINGVIHSAGIEASGLLEHGTSQDWRHVMAAKVSGTQQLMTAMSQDPDFVLLC-SSLASFVGGIGQADYAAANR
YLDAVAYYWR-QQAIPVTSVNWDTWAEVGMAVDYAARRQE---------SVTGL----------------------------------SNQEGCAIFDLA
IAG-----------MEA--QIVVSKFTTVRRAQLQNSSV--------------IS------D----SASPEEAVRQLWYELLGEETIHLEDDFFELGGHS
LLATQMISRLRDHFQHCLTLAEFLEQPTMARVV-----------------
>tr|A0A0Q4QU18|A0A0Q4QU18_9BACL Uncharacterized protein OS=Paenibacillus sp. Leaf72 GN=ASF12_16660 PE=4 SV=1
-----MKWMEEAADQLTRAMRGETVI---ILGEWQQLTQQLEEEGHCIQVKRGTHYQVVSPQSYMI-SENEEDYDKLTEALK--HVKFTKILHLLCCNGP
DGMMSAEQLSERQSLGVYSLFHLTKALLN--AGVEIIIAADYVNRVTGEETLKPENSPLFGLGKVIGIEYPHITCKAIDMD--ALTTARDVISELG----
RNKTTYQIAYRDGKRFAEIMEETDVEQLPDDPVS-IKEEGVYVITGGAGNLGLLTAKHLASKGKINVALLNRSPLSRLHD----TIKKLHEIAA-TGAQV
ECISLNVTSLDEMSATMERLRQTYG-KINGVIHAAGVAGRGFLIRKDTAVFEEVLNPKVMGTWVLDKVTEQDDLDFFVLFSSGVALVGEMGQGDYTAANC
YLDAFADYRR-KLGKPALSINWVVWDGARMGEGTSIDSIF-----KTLPATLALQGFDKVISKA---------ITRVLIGEVNTSN----PSG--LELFS
----KDVFH-LPEKLRAIMFSDSSSEQAVQSKPLPMQEVK-------------VKLLGSK---NGSYSEVEQTLAGLYREVLGYEELSINDTFFELGGDS
VQLHRLHKLVDQRYTGQTSIADLFAYASIAKLASFLTKE-----------
>tr|S9UUF1|S9UUF1_PAEAL Beta-ketoacyl synthase OS=Paenibacillus alvei A6-6i-x GN=PAAL66ix_05009 PE=4 SV=1
-----MEWFQDQVQQHTNSLTGETIL---ILGTWDALTERLREEGNCIQVIPGDEYQIVSDRTYVI-GKREEDYANFIQHVVQSEIHITKVIHLFTLNRN
RLITNLDELDEVQNDGVRSLFHLTKALLN--SRMEIFIVSDYVNKVTGKEKIKPENAPLFGLGKVIGIEYPHLQCRAIDLD--ESASVHDLLSEIK----
TNRYTYQIALRNGIRFAEMMTESRIEAANERDVS-IKEDGVYVITGGTGKLGLQMAKHLASKGKINLALINRSCFAPLSE----KIELLTEIQS-RGAHV
ECLALDIASMIEVSHTFERLRQKYG-RINGIIHAAGVAGRGFLIGKNQTVFDEVLHAKVYGTWVLDKVTEKDNLDFFVLFSSGVALSGELGQGDYTAANC
YLDAYAEHRS-LIGKSTLSINWVVWKGARMEEGNSIDSIF-----KAIPIHQALQAFDKVLNKD---------ISRVLIGELNPAP----TEN--LELFS
----NKVFH-LSDRIQNVLNRSEG--KLREISPMATSKPD-------------IKLTGNE---AGDYTDIEKKLALLYREVLGYNELNTNDSFFELGGDS
VQLHRLHKLMEQEYPGRVAIADLFTYSSISRLAAFIKQN-----------
>tr|E1UUN3|E1UUN3_BACAS Bacillaene synthesis polyketide synthase of type I OS=Bacillus amyloliquefaciens (strain ATCC 23350 / DSM 7 / BCRC 11601 / NBRC
----EPVWKEQQKPAQEHPSYEQHIIFLCEYDEA--V------KQAIEAKLEHASVFILDERPASIAERYHSYAGQLFDHI-------K-----------
--TIMKGKP-----KGRILLQAVTRSAGL--QQ--------------------VF-SGITGLFRTACLEHSKLIFQMIEAD--EKESAEDIAEKVSENHM
HAESVHV-KYENGKRFAADWEEVDIQAEP---DIPWKDEGVYLITGGAGGLGLIFAKEIANRKDAVIILTGR---SALGEKQQDLLETV----RAAGASV
FYEQTDVTDEAEVYRFIRNIRKRHG-KLDGIVHSAGIIKDNYMVKKPAEEYQDVLAPKVKGLVYLDEASQHEKDVFI-VFSSLSGVLGSVGQADYASANV
FMEMYAAYRRSLRYGKTLSVSWPLWKEGGMQAGKQTEILMQEAGIAPLSTEAGIKALYQGLMSGAVRVTVLE------------------------GDVK
--NMK---AKLFRK----ENDHPEAESGVHHEI------------DADSLLEKVK----------------HLLKQQTASLLKLDKIDAHEEMTKYGLDS
ISMTEFTNQLNKTYRLRLTPTIFFDHPTIHEFAVHLISE-----------
>tr|F1TDH7|F1TDH7_9FIRM AMP-dependent synthetase and ligase OS=[Clostridium] papyrosolvens DSM 2782 GN=Cpap_1809 PE=4 SV=1
----KKIWCKAELNISGKQEVENVLVFDTDNELA--L------MQQYKTVMPGENFLQLDERTFKICAGKKDDENDIYDDSNISKFLTQ-----------
--ALLSQKI-----EGIVKLLYYQEGTSFT-AP--------------------FD-SAISGFVKTLYKENPNYIFKCIGLD--EIKASQNLVRLA-INEF
NNEDFEI-RYKENERKVKALQTVEVTKNG---ILPIKKEGIYLITGGLGGVGMIFAEYFAKEYNATLILTGR---SPLDEKTSLKLEKL----KLSSNKI
IYIQSDISDKAQVVELNESIMGKYG-SVNGVIHAAGQLKDSFIIKKNSKEIAEVLSSKIFGTLNLHKTFNSSNDFFV-LFSSVSAEEGLIGQADYAYANS
FMDNFAQ-----SCSNVISINWGLWNNGGMKMGGHNAQMSSKNGMLEISADEGITMFSSALTMKEASIVATV------------------------KDLG
--NTT---QDLIKK----TKSDSS-D--NQLST------------GSDKVQELAW----------------NYFANLISEETPLKEISLKEPFRTFGIDS
IMSLNMVEKLEKSFGL-LSKTLFYENQTIEELIAYFIKN-----------
>tr|B2IYP4|B2IYP4_NOSP7 Beta-ketoacyl synthase OS=Nostoc punctiforme (strain ATCC 29133 / PCC 73102) GN=Npun_F3169 PE=4 SV=1
DWLYQITWQLQGRTITQSSLVQYWILLIDEDAVGTELAKLFQAKGSCVAVIPSYTYQSLEQGKIYINPAEPQHFDRLLQEVSIQPGIALHIVHLWSLATG
D-L-----LDSTQMRICGSVLHLTQALARINFP--LARLWLISRGSQSILQSEIAQTPLWGLGRVIATEYSEVFAGLIDLDPQSST--VEAATQLWAEFS
HPELGEQVALRGNQRYVSRLQRVPNTIDF--SASFNPSLGTYLITGGLGGLGLTVANWLVERGVQHLVLVGRRSPSDK---AKSAIASWEN----AGVQV
TVTQADITQLEQIQKILEGIEPQ--FPLRGVIHAAGILDDGILLQQNWERFTRVMAPKLQGAWNLHILTQDKPLELFVLFSSVASVLGTTGQANYAAANA
FLDGLADYRR-FQGLAGLSINWGAWAEVGMATGSPV-------GVEKILPQQGLQI-LAALTHQANAAVLPVRWSKFIAHYYTQ--------K-VPPLLS
------E----------FVDSRQTQEQPVLAYILRQLQE--------AHTADIQ-------------QILFNYIRDEVAKILRFNSLQLRQRLFEVGLDS
LMAIELRNRLQSSLECSLPTTLLFDYPTLETLTKYLTND-----------
>tr|A0A0N0D6X1|A0A0N0D6X1_9DELT Short-chain dehydrogenase OS=Candidatus Magnetomorum sp. HK-1 GN=MHK_001061 PE=4 SV=1
NLFYSIEWEKREISRPTD---SSYLIFSDEKGTGNQLSQYLARKNSHLQVSKN-----------NLNHDFSQNFIRLFETFEQNNDSEFNILFLRGLTDD
D-SVE--IMRKKINNLYENLLSFVQSVINKWKH--LPRIWLITRNAWNIQMHQIEQTGIWGIGRVIALEHTDMWGGCIDLDNCESD--NWVEAL-LTAVS
SIANNDQIAVRNNSLYVARLKGAPIPSNK--ENQFVKSDATYLVTGGLGALGLRTAERLFHCGAKNIVLLGRSTPEKG---AKKRIEALKQ----EGVRI
EIFQADVSDETVMAEVFNSIQKNM-PPLLGIVHAAGVLDDGILIKQNPMRFNEVLSPKIFGSWNLHLLTKDIPLDFFVMFSSSSAITGNQGQGNYAAANA
FMNGLAYYRR-TKGLVATSISWGPWAGIGMATNIQDK-----VGLRLIPMETGLEI-FENLIG-VNISVMDLDVNVFTARNYLE--------K-T-DFFS
------N----------YIRSKSLSEEKTKYELVNKLKN--------APFEART-------------ENMISFLLEITKQ--VIGNIISDRPIMDMGFDS
LMIMELRNRISSELGKKLPVSILFDYPTLDSLANHLIQN-----------
>tr|D9XDI5|D9XDI5_STRVR Type I polyketide synthase (Fragment) OS=Streptomyces viridochromogenes DSM 40736 GN=SSQG_00882 PE=4 SV=1
--------------------------------------------------------------------------------VAAAGADTVV----WPLVAD
GDDGAVGGIAGLARVELARVLERVQAADERLAGTRLVVVTRGALAAQPGEQTDLVHAGVWGLLRTAQTENPGRVVLV-DA--D------A-EGYAQLPLA
LAVGETQLAVRDRRLLVPRLARARAASPQEAAAPRW-DEGTVLVTGATGTLGRLLTRHLVEHGARRLLLLSRRGANAPE--AGELRAEM----ERLGAQV
SFAACDAADRRQLATALAEIPDE--SPLTAVVHTAGVLDDTVLSGLTAERLDAVVRPKIDAAWNLHELTRHLPLSAFVVYSSLAGLIGNAGQANYAAGNT
FLDALAQHRR-ALGLPATSLAWGLWSQTSTISGQLTDRRIARLGLRALPSDEAMSLFDAALLTGEPVLVTYLDTGELRR-------------------QG
DEVLPV----LRDLAP---AGPR----------P---KTAGHAQGGGSTLVRRLAALDAD----ARHAALLELVCGRVAGVLNAAAIDADRPFQELGFDS
LTAVELRNQLGRATDLRLPTTLVFDHPTPTALARQLARE-----------
>tr|S3C7U8|S3C7U8_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. HPH0547 GN=HMPREF1486_00434 PE=4 SV=1
--------------------------------------------------------------------------------LRESGAEVTE----VVLGAD
LDRQRVGGLDERPSTGLVLNIALMQAVGEWEEPVAVWLCTQDSVAAARTDRSHSVQSSSWGLGLVFGLEYPQWWGGLVDLPAV------D-VACLTSVLG
AGDHEDQVAIRDGGALLRRLRRKPLAHESG---EPFRTSGTALITGGTGGLGAHTARWLATCGAEHLVLTSRRGLDAPG--AGELVTGL----EALGTRV
TVAACDVCDYDALARLVEQVEADG-PPIRTVVHTAGVGEPGSLAGTDLAEFEAGAAAKLMGTAHLDRLFDREGLDAFVLYSSVAAVWGAGEHASYSAGNA
YLDSVTRSRR-ARGLAGTTIAWGLWSADDGLGGSIDT---SWRGLSFMNPRTAVAGLRQALADDEEFLIGDVDWEAFTPA------------------FT
AARPRP----LLDAMP---EVRA----------VL-DADDGDDTGEGNSLRERLHPLAVE----DREKALRDLVRTHTAEVLTAHTVEEERPFRDLGFDS
LLAVELRNALRTATGLKLPTTLVFDHPDVIRLAQHLNTL-----------
>tr|A0A0M2ZPP5|A0A0M2ZPP5_9MYCO Polyketide synthase OS=Mycobacterium elephantis GN=AAV95_03410 PE=4 SV=1
--------------------------------------------------------------------------------LRGASPGSEVRI-VHVAALD
ADPAGPTSM---QHRILGGTRRLFNAVAAAELRAPVWMVTRGAQRVTDADAVAPDQSCLWGFGRAASLEVPQVWGGLADLAGE------WSIDRIAAPRD
TGLVEDQVALRDQNLYVPRLIRRAAPPEPT--SLQLRADATYLVTGGLGALGLAIAGHLAAHGAKHLVLSSRRTPGEDA--QQRIDALA----GQYACDI
RVISADVADAHDVARLLARVAADL-PPLAGVVHAAGEVSTTPMSSMTDAEVDRVFAGKVWGAWHLSEAAADLQLDFFVSTSSIASVWGGFGQTAYAAANA
FLDGLAWRMR-AQGTAATSLNFGPWAA-----GMADAARLDQRGIKTLSPADALAGLADVVASTPGQAVARIDWATFLPL------------------YQ
QAGRRA----FLAELE---REAP----------TQ-PSAASATPSRQTRFVEQLAAAPVQ----QRKRLVTNYLRDAVAEVTDVAEIREDAGFFDLGMDS
LMAVELRRRIEHGVGEEIPVTLVMDHPRLSDAADYLLGD-----------
>tr|A0A0R3F5T9|A0A0R3F5T9_9MYCO Polyketide synthase OS=Mycobacterium sp. H002 GN=AOT84_25715 PE=4 SV=1
--------------------------------------------------------------------------------LRAA--DSALRI-VHVAALD
---GGVSSI---QHQILGGTRRLFRAAAAAELRAPIWVITLGAQRITDTDTVAPEQSALWGFGRAAALELPQVWGGLADLAAE------WSISRASASTD
AAAREDQIALRDQSVYVPRLVRREYLPSGT--PLEIRDNGTYLVTGGLGSIGLEIAGYLAACGAKNLVLTSRREPNEAA--QQRIDALG----AQHGCEV
RVVTADVADAHDVARLLAGVQAEL-PPLAGIVHAAGEIGTTPLSDLDDTEVDRVFAGKVWGAWHLSEAAADLKLDFFISTSSIASVWGGFGQTAYSAANA
FLDGLAWRLR-EQGVAGTSVNFGPWTA-----GMADAARLEQRGIKTLSPSDALAGLADVVANGGAQGVARIDWARFLPL------------------YQ
QAGRRA----FLAELE---REVP----------SH-LATSQ-AQSGTTQLVERLAGAPVQ----QRKKLLTDYLRDAVAEVTDVSEIREDAGFFDLGMDS
LMAVELRQRMEQGVGKEIPVTLVMDHPRISDVADYLLGE-----------
>tr|X5LHZ1|X5LHZ1_9MYCO Polyketide synthase OS=Mycobacterium vulneris GN=BN979_03594 PE=4 SV=1
--------------------------------------------------------------------------------LRAA--DATLRI-IHVAGLD
--SGGAPSM---QHQVLAGTRRLFRAAVAADLRAPIWLVTRGAQHVTDADTVTPEQSALWGFGRAAALELPQLWGGLADLSDE------WALSRVTTGSD
AASKEDQLALRGQAVYVPRLVRPEDLPSGN--PLALRDNATYLVTGGLGSIGLEVAGYLAAHGAKQLVLTSRREPGDAA--QKRIDALR----AQHGCEI
RVATADVADAHDVARLLAGVRAEL-PPLAGIVHAAGENGTTPLSELDDAEVDRVFAGKVWGAWHLSEAVADENLDFFISTSSIASVWGGFGQTAYSAANA
FLDGLAWRLR-KQGIAGTSVNFGPWSA-----GMADAARLEQRGIKTLSPSDALAGLADVVAHGPAQGIARIDWSRFLPL------------------YQ
QAGRRA----FLAELE---RELP----------AQ-VGATS-TASGTTKLVEQLKNAPVQ----QRKKLLTDYLRESVAEVTDTAEIREDAGFFDLGMDS
LMAVELRRRMEQGVGAEIPVTLVMDYPRISDVADYLLGD-----------
>tr|F1TBP2|F1TBP2_9FIRM Acyl transferase OS=[Clostridium] papyrosolvens DSM 2782 GN=Cpap_2599 PE=4 SV=1
------------------------------------LEEYLRHKGTVVRVKKGLFYNAEA-YGYTINYSNSEDYEKLMQDIYKSGEKFRGVIHIP-LHER
NELLGSEL---NTDSGVFVHMYLAKAILA--AKISLKLITFNGLAVPADKSVVPESALLVGLDRNIPYEVKNISSLAIDFNRNISN--EDFANKLIYELS
FRSKFKEISYRNNERFIRITREFEGNINE---TGCSTDGGVYLITGGLSGLGAIFAEYFIRNNAEAVYLTGRRDIKELTDSKASELEKLNNINIKNNTAI
EYRKSDVSNPESLDSVVK-EITSKYGRITGIVHCAGLVDSVTLRTKTYESFAKTISPKFQGTMNIGRAFMNILDFMILSSISGLNGKLGATLCDYAAANF
YMNEYAKALAQNSGKKVVSVSWPLWEGVGLGAKKAYGGESSDMGLKIFDA----------V-----------IKSKNCGNLIV---------------LN
TDKSDFSLNGLFKEEETL-----TFEKAADMKT-------------------------SDVDKAASRESLKEYLKGLLVEFIEVSQISEYTNFSEYGIDS
VIVADIVAVIERKYKIFLHPSIILEYPTINALADFLMEE-----------
>tr|H2JGN3|H2JGN3_9CLOT Amino acid adenylation enzyme/thioester reductase family protein OS=Clostridium sp. BNL1100 GN=Clo1100_2633 PE=4 SV=1
-WFFVPSWRRANLSYSNKHTLKNILVFINYTEFSNNLVRSLESAVKLTFVKIGTSFCQDKESGYFINPGKNTDYKNLFNELHKSENIPDTILYLWTLTE-
-DNLHQPKVNTAFDIGFYGLIYIAQAIGELNIPISINVVTNNMHLVSGEENINPEKAVIVGPIRTIPKEYSNIKCTGIDIEVPQEDKTKETINCLLAEMA
ITDNDSLVAYRGKYRWIQSFNQIQLKECHGVPSR-LRENGVYVITGGLGGIGLAISEYLAGTVRARLVLIGRTEIPPREN-WDDYINSPEKELEELGAEV
LPINADVSDNYQMSKAMSTIHERFG-EVNGIIHSAGLPDGGLIQLRNRKTTDSIMSSKIQGTLEVNRFIEHNKDFMIYCSSLSSIIAP-FGQIGYCSANN
FQDAFSQHQC-NKGYYTVSINWDTWKQVGMAVNLTCNGILISEGIEV------FKRILD---SDLPDYLL--------AQVLI-----SPYPLEVY--LK
---------RIWD----TERE--------QYK----IKSEENYNPEECMNLQ----------DITSQSEIESKLTAILKEILGYPDIGRDDNFFDLGAYS
LHLIQLRQRLKAVLNIDISIVSLYANTTISSLSRYLSKRD----------
>tr|H8MFK7|H8MFK7_CORCM Malonyl CoA-acyl carrier protein transacylase OS=Corallococcus coralloides (strain ATCC 25202 / DSM 2259 / NBRC 100086 / M2) GN=ppsE6 PE=4 SV=1
DWFYAPSWKLSPLPKA-KDAAGKWLVLADDTGVAEALAPKLG--GDVFRVVPGARFEQRPDGTFTVDPARREDFCSVLEALKKQGRAFSNVVHLWGLSHE
P-----ASQEKALDLGFHSQLFLARALSETGHLEPLTWSVVTSRSARVEQAQLPEQALLVGPSRVLPQEYPNLSCRFVDMVP--SD-AGAVVDRLAAELG
AEPRDAVVALRGRQRWVQTFEPVRLEAAG---AEVLRDGGAYLITDGLTGIGHALASELATVHQAKLTLVETPDQDAVSRRIQ------RALALERTGVM
LVLPASLTDVESMRGVVD-AAVARFGQIDGVIHAAGGMQGATLAETGPDECAWHFRPQVHGVRVLEEVLPKEGPAFCLLVSSLSSVLGGLGQVAQASASA
FMDAFAEA-R-TEGFAWLSVDWDAWQAQAMAELSP---TLAQF---AIQPAEGLEALRRALSHGESAVSTGD--------------------------L-
-----------------AARRRQ-GPRAA---K------AEKGKKDAAKGNARPSI---LTPYAAPRTELEKTVAGIWEQVLGIDGIGINDNFFELGGHS
LLATQLRNHIHAVLKVDLSLRGLFETPTVAGVAGR---------------
>tr|R4K3I5|R4K3I5_CLOPA Polyketide synthase family protein OS=Clostridium pasteurianum BC1 GN=Clopa_1305 PE=4 SV=1
-WFYKWQWQEEVNIPQEKIEEGAVIIFNDPKGIGSELSKFSEAVNPVYFVEAGEEFKYDGKNNFVINPSKKDDYDNIIKNLSH---KLSLIIHLWNLPYS
EEAITSSKDNFL-YESLYSVFNIAQAVKA-EVKNNISFIVVTDRAQLINHAPHQS--LAAVLAQAIDEDNTNINSQIIDIDIKEYINTLEIGDKLFIEFN
KKVDPGISVIRDNKSFVRKLERFK-ASGDKLK---INQGETYLITGGTSPLGGDLAKELAKQANINLILTGRSALPEVSNEIKEKINLIL-DLEKLGAKV
LYASVDVTNKAEMEKLVSKINDQYG-NIQGVVHAAGVLDYSSLLNKNVDILKKVFAPKVQGTVITDLVTRKEPLKFFISSVSASKKKWSQGLGEYAAANS
FLNAYTNYRN-SIGAKTIAINYSLWDNKGMGAGESTASAIKAQGLKPLSPEKAAKAFIEAIAVKESNIHI-IDLLKENIVEKVQN--TDR----------
-------SEQV----------TAAEHREVSYLEAKEVKNTVY---------QVI---GKQ--------------LEIP-----AEELDIGTNFLELGLDS
LGAIKVIEKLSKALKVELYPTIIFEYQTPEALGNYIEN------------
>tr|A0A0H3J6A9|A0A0H3J6A9_CLOPA Erythronolide synthase, modules 5 and 6 OS=Clostridium pasteurianum DSM 525 = ATCC 6013 GN=eryA PE=4 SV=1
-WFYRWHWQEAAEIPEKKIDPGAVIIFSDSKGIGNEISRFNQERNPIYFVEAGEEFKYEGKNKFIVNPDKKEDYINIIKNLPH---NLSAIIHLWNLPYS
EEDLVLSKDKLL-QESVYSIFNIAQAAKA-EREENINLIVVTDRAQLINDTPHQS--IAAVLAQSIDEDNTDITSKIVDIDINEYVSAVEAADRLFHEFN
SKSDSRISVIRENKSFIRKLDTFK-PSIEKVK---INSGETYLITGGTSSLGGDLAKELAKQANINLILTGRTALPKCSEDIREKINLIC-DLEKLGAEV
MYVSVDVTDKDKMKDLINAIDNKYG-SIQGVIHAAGVLDHSSLLNKNTEILKKVFAPKFQGTIITDLVTRKEPLKFFISSVSASKKKWSQGLGEYAAANS
YLNAYSNYRN-GIGAKTIVVNYSLWDNKGMGAGETAGNAVKAQGLKPLSPKKAAQIFIEAISVSESNVHV-MDLIKESIVKKPEN--KI-----------
-------IEDI----------ALSTAEEVSYLAVKEVKEIVY---------KII---GEQ--------------LDIS-----VDELDIGMNFLELGMDS
VGAIKVIEKLSKELKVQLYPTIIFEYQTPETLANHIEK------------
>tr|A0A0D5DB84|A0A0D5DB84_BURGA Polyketide synthase PksJ OS=Burkholderia gladioli GN=pksJ PE=4 SV=1
--------------------------------------------------------------------------AQLLGELSAVLADCEVAPVV------
GEDLGAR-----YHGLARHVFLRLQALAA--EKPASDVL---VQVVVPLTGELAVLAGLSGLLKTLGYPRLRTQLLCLPAEMNGVVMGDRLRE--EGEQA
EPA--ALLRYRDGVREVRVARELVQTP----ARPIWREDGVYLITGGAGAIGLVFAGEILARAPRARVILSSRSALD--EVSQARLAA-------LGERV
VHRRLDVTDAAAVSALVEGIVVEYG-RLDGVLHGAGLLRDAYLANKSVAELDAVLAPKVAGVVNLDRATRDVPLELFVTFSSLAGYGGNPGQADYAAANA
FMDHYVIARA-ERVGRSVSVNWPLWAQGAMRPDAAVELMRRTAGLVPLENEAALAAFAQAVMGDAAQVLAAGEREKLLALFGA--AGDQADD---D-GFE
AEQDA---DEAYR---------A-NPAAAPAV--EITAARSPAAGGADLSRMVS-----------------AALLDQASVLIKVKDIDLDEELAGYGFDS
ISLTELATELNRTYELDLMPTVFFEHPTLAALTAYLVDA-----------
>tr|A0A0F4Q905|A0A0F4Q905_PSEO7 Thioester reductase OS=Pseudoalteromonas piscicida GN=TW73_06115 PE=4 SV=1
-------------------------LIMDSHGVAEELASQMLNGHTVYRAYSAEGFNRLDDQSFNIDIGNSQDYETLLEVINK-EVQLDRVVHLLGVTAT
ENMLSMTQFNQAQRYGAYSALYTVQAIVKLDDKLSIDFITNDVERVTGDETLNIGKSTIKGLCKVAPQEYPELSCHHIDVHLNQA--TRDHAIRLSLELH
SQQRAPLVALRGNQRWEPDYETELIDTET-PAAHRLVDGGVYFITGGLGNIGLLLANYISQAVAPKLVLVGRSEFPELEPKQIEQIT----QVEKSGAEV
LILSADSANLQQMQDAMNVVESQFG-AISGVIHAAGQLHGSMTAETTEDDFEKQYCAKANGVIVLETLLQKRQVDFCILMSSLSSVLGGLGFSAYAAGNQ
FMDAFVQSKHEQGDERWVSVNWDGWSFTEATQD-----------DFSMTPEEGVEAFAA-MMSI-----------------AYHPQ-------L------
VNSTGALEKRLSQWIDKKVTESQQ---------------------------ALYERPDLESDYIAPRNEVEEKLVAIWQQVLGIEQIGIEDNFFDLGGDS
LVVTRVISEIRKIFSVALSIKEFFEKPIISQLSEKIAAE-----------
>tr|A0A0Q4QU18|A0A0Q4QU18_9BACL Uncharacterized protein OS=Paenibacillus sp. Leaf72 GN=ASF12_16660 PE=4 SV=1
------------------PAAGVTVIVKDSEGFADRLASALRDQGRQVLLAEIPDLSATE-EMGEIEAKWLDRYSQLLQEEAEQGIA--QIIHCGSLAGS
V-ISSIDELKASQQRGAMSLFLLMKAWAAFEHDTEVIVLTENACRITGEEQLRPENAPLLGLAKALSKEHANIRCRSIDMDGE------VQLEEILSELS
INSDARLVAFRNGIRYVELFEPCSLNESS-SEELTVQAGGVYLITGGTGGIGLETAKWLSRKGRIKLVLINRSELPDLNNKLCEKIASIREIEA-GGSEV
ILYRCDVSQYDETAAMLEHIRLTHG-EIKGIVHGAGIARTESIMEKSLDTFEQVIRAKIYGTWLLDQLTLQDQDFFLMYSSIATMFETG-YQSDYLAANA
YLDAYSMAPS-SDGRRRLTINWTTWQGKGMASDHNF-------QADTIFKARAME-LLDAVW-------------QTRQNVLIGELNLE-SRMALWLNYA
----IQLSDDITA-SLDALNERLAQTP------ERS---SK------SAGYAAVKLIGSEHD---AFSETERQVAQTCKGVLGFSEIDIHESFFEMGADS
LMIRQIYQKLSQLYTEEVVITDMFEYPTVHKLAKHIERR-----------
>tr|S9UUF1|S9UUF1_PAEAL Beta-ketoacyl synthase OS=Paenibacillus alvei A6-6i-x GN=PAAL66ix_05009 PE=4 SV=1
------------------KTSGAVVILTNDGEWSKQLIERIELSGKVVL--KIPVFRKNM-PLAYDEHAYLHDMEGLLTGFHASGIS--QIIHCGSLMMG
K-VATLNDLEVSQQQGSLSLFLLMKAWLKFEHDVEVVLVSEYVYTVTGKEKCRPENAPLFGLGKALSKEHPNVKCRIIDIDES------TGIENLLDEMN
EGNDSNVVALRNGQRYEPTFEEYFLDSSE-QEYCSVQPGGVYIITGGTGSIGLDTANLLATKGRIKLVLVNRSLFPDASGKLCDKIRMIRLIES-KGSDV
ILYRTDISKVDQLTIMLNEIRSQFG-EIKGIVHGAGLTKVEPLTEKSIDTFQEVMSSKVYGTWLLDHMTSTDKDFFLMYSSIATWFETG-FQSDYIAANA
YIDSYSAMSS-PDGRKRMVINWTTWKDKGMASDNRF-------QIDTIFKTKAIE-ILEQVW-------------NQPIQLLIGEINYE-SSMALWLNYS
----YHLSEQIVQ-KLSCVQHRMNSER------EDA---RE------NSIINRVNLIGSHSD---ISGQTAQTIAEICREVLGFMDIDIHESFFEMGADS
LHMKQFFQKLNKYYPGKALITDLFEYPTIYKLSQYIDQQ-----------
>tr|B8I5H3|B8I5H3_CLOCE Beta-ketoacyl synthase OS=Clostridium cellulolyticum (strain ATCC 35319 / DSM 5812 / JCM 6584 / H10) GN=Ccel_2376 PE=4 SV=1
-------------------------IFMDAEGIGEGLASNLTDKGDVIQVMLGESYEKKNELSYTI-SGCERDYYKLFEDMGDRRIS--KIIHLFGNRSK
QYGDSPEELELSHITGVYSLFYMVKSFAKLKSGVEMVLVSRNTFSVDKQEKANPGNAALFALGRVISAEYENIRCRGVDIDTD-TD-----ANSLVSEVY
GYNTSYLTAIRDGKRYIQEFARLEMGG-GSRKGIDIKSQGVYIITGGLGGIGLEIARHLSQKGAGNIALVNRSSMPELKAKLCQRINAINSIEADGTAVF
SYP-GDISVKDQMMGVINEIRD-KFNNINGIIHCAGLAGEGLISGKSQADLSKVLSPKIEGTFMLDNVTREDEIDFFVTFSSVMSILNVPGQGDYAAANA
FMDSFAQWRS-TQGKRTVSISWPAWKDTGMAAEYKANKSL----FKPISVEQALSDFELILESESTHVIAGLDF------EMLSGISED------IQLFK
------LEK----DIAAELESTVSSNSSVKESPLPTVKL-----------------KG---GVSGNYTKLEKLIGNIWGAILEIGELSIHDDFYDLGGNS
LLSINMASKLKEQLNVEIDINNLFEHFSIVDLAMFISEK-----------
>tr|A0A0G3VAC3|A0A0G3VAC3_BACAM Macrolactin polyketide synthase MlnE OS=Bacillus amyloliquefaciens GN=ABH13_1459 PE=4 SV=1
------------------------------------------YEAPFIYVTSGERFEDCRNGRFTMNFAKDEDYDALCGVLRSQNIRPRHIIHFLAAGLF
K---NTEDAMRKQLNKSLYSLFMFQAANKLCPKAEILYLYE---NAEGEVQPIY--NAVESFLKTVQAENPNFTCKAAELKFDEPFTKQHIADVISFEWN
NKTDHF-TCY----------EPRHYYKRQRVKKHSVKKNGVYLITGGAGGLGYLFAEYLAKQAEVKLILTGRSPASR---ETAQKLSALEN----LGAKA
LYVPADISKEKETDALIKHIKQTFG-ELNGILHSAGLVKDAFIIKKTKESIEEVIAPKVFGTVWLDKAAEEEPLDFFVMFSSLSAVLPNAGQSDYAFANG
CMDGFTQYRSKGRPGKTLSINWPLWDAGNMTVGPGELQALRHAGLELLSAQAGLAAFQDSMSRSASQLA-VISGDKDRISELLSTDH-------------
---KKI----------------------------ETVPENNSNLPQL-HEKDL-----------------KKQTVRLLTEIVGVDSILPEDTFDRYGIDS
LTILGLNSRLEKYF-GRVSKTLFFEYSSVEELSEYFLEH-----------
>tr|W4BAM4|W4BAM4_9BACL Beta-ketoacyl synthase family protein,phosphopantetheine-containing protein OS=Paenibacillus sp. FSL R5-192 GN=C161_02755 PE=4 
---YELVWQQKGIAKGDSISDGTTLVLLDGSDYAAEIAARMESGMQVYSVL-------QT-DVLRSDPDSVEAYERVLQQ---VGLDLSRIVYLNGVGSE
EHSASMESLESVLNERVYGFFRFIRALLSSSQPIELVLISREVNSGTERMKPH--LASAFGMGRVVGKENIQIHCRCIDIDEG------SSLDLLLKEIG
TSSSYYEVAYRNGTRYVQEFRALNESAPP-EDELVFDNDGVYIITGGTGGIGLETARYLASDAPVNLALISRTPMPAREAEQSHQITVIREL-ESRGHQV
SCHAADVSDLDAMRVLLDQLRVTFG-KIKGIVHGAGVGSSEMITSRSQAGFTEVFSPKVHGTWVLDQLTEQDHLDFMVLYIASVFSAPGQ--ADYIAANA
YLDAYADYRS-MMGKRTLTVQWSTWKETGMSAEFAVDTLFK-----AMPTEQAMNQLSLVMRSSVRRVLIGQIEGQLISALAK-------------SPFD
----------LSSSIRVQLDQRMKQLASKRLP--ASSSEDRDGEV----------VLTGK--SDASYTPTEKALATICKTMLGFHEINVGDSFFEMGADS
IVLIQVQARIDQQFPGLTKVTDLFANSNITRLARFMDEK-----------
>tr|A0A0Q4QSK7|A0A0Q4QSK7_9BACL Uncharacterized protein OS=Paenibacillus sp. Leaf72 GN=ASF12_16670 PE=4 SV=1
---YGGQWVRQEQLMAE-QQAGPVLIFMDEKGLGQSLAAEWNRGTKTVQVY-------LRKQYAKLDDGSVDDYVLLLKD---NKGTWSKIIHLFSIVPE
----GWNSFNETQYRGVYSLFYLSKAVAQVSAVTDTVIISDYVDVGRERVNPW--NAPLLALGKSARQELPSMLCRAIDIDEA------TSLDTIIREIG
AAPSYYMVAFRDNERYAEIFKEYRVQEAN-EQPIEVKEEGIYLITGGTGGMGIETAKYLAARKKVNIALINRTPLPDKADRNSQRIKAVREI-EAMGAHV
ECYSLDIANMQQMEELVGGLRARYG-RINGIVHGAGVGGDGFLYLKEEQVFNEVVHPKVFGTWILDKLTEQDRPDFFLMFMSSRFAVPGQ--GDYCAANT
FLDAFAKYKT-LNQQKALSINWVAWKETGMAVEVNADGAFK-----ALPTAVAMRGLDEALNRSVSNVLIGELGSDLLWELGL-------------VPQL
----------LDSPIDAAITGSQKRWEARQLA----SQRRFEGEI----------KLTGK---DGDYTDLETKLAEIYCQVLGFNEIDMDDNFFELGGDS
ILLGRVHASLEKHYPGKVRLLDLFEYTSVSKLQQYMRED-----------
>tr|A0A0L7ZFR4|A0A0L7ZFR4_VIBAL Uncharacterized protein OS=Vibrio alginolyticus GN=ACS86_00615 PE=4 SV=1
-----------------------WLIFSDGAGFGAVLAHLLEERGSVVCVEQGSAFSQNGAYQFTVKAGASDDIDRVLSTLKRQNWFPDHLAYMWPLDQQ
AASDCSSQLEWCEQHALMDIQAITRLGRALVDCYLLTHRGAIASDAALG--HGSQ-VALSALCQVIAQEDPLFQIHQIDLDQP---SLDDVAMSLLLDLY
AKEKPPRVAYRDGVRMVPELVR--LPTDT---TPFSLSSGTYVITGGLGRIGLSLAAQLAMACPCHLVLLTRQDFTDLSDEMKVTLRQLQALERE-GVTV
SVLQSDVTDLAQLRGTLDAVTQEFG-AIKGIIHCAGQV-EGLSTQITAADLAAQALPKMAGARNLQTVCQDVPVEFVVLMSSISTVLGGLGYSAYAAANA
WMDSLAFSERHNEVTRWRTINWDTWLF-DS-----SQGAQHGNGIPGMDPSEGLAVIEAALNQSEPLIYAAGD---------------------------
------VEARLAKWVHRQSREAQ-----------------SVGTVA--------ASSTQAS--SLPR-AHEASLRDIWHELLGVEHIGPEDTFFDLGGDS
LLATRLVSLIRQRCGVEVSIEQIYQSADFAGLATLLEAG-----------
>tr|Q08PV2|Q08PV2_STIAD Uncharacterized protein (Fragment) OS=Stigmatella aurantiaca (strain DW4/3-1) GN=STIAU_0242 PE=4 SV=1
-WLYTLEWKRHEGLEHGPEGTGAWLVLSDTTGTGQSLAELMQARGRCVLVTAADRYAQLGPGRFQVNAAAPEDYRRVLKDFGEAG-GCRGLIHLWSLDTG
G----LEDLEPAQRLGSQSALYLAQAVVR-EGGRDTPRLWLVTQGASQGERVSVAQAPLWGFGRALSLEHPELQTTLVDVVAD---APRAQAQALWAEMG
AADGETQIAWRQGTRSVARLVRGTYDTGA--VLPSLHANATYLITGGLGGLGLTLAKWMVTRGARHLVLVGRGEP-SPTA--RTVLRELE----EAGATV
VVERADVANRAQMAGVLGRI-HHEQHPLKGLVHAAAVLDDGTMLELDAERFHRPMNAKGHGAWNLHTLTAGWELDFFVMYSSAASLLGFPGQSNYAAANA
FMDALAWHRR-GQGLPGLSINWGAFAEVGMAAQSNRGERLRHRGVGSLKPEQGTAVLERLLAGSSAQVAV--------------MQLEARQWLEFYPNAS
----APLWTVLLAEQAK--------TK-SREST-----------------SVRFREALSKAEPSQRGALVEEHLAEQIALVLEPSKIDRLRALGELGLDS
LMSLELRNRLEAALGMKLSATLLFTYPNLASLAQHVVGR-----------
>tr|A0A0A0NG10|A0A0A0NG10_9ACTN Uncharacterized protein OS=Streptomyces rapamycinicus NRRL 5491 GN=M271_08650 PE=4 SV=1
----------------------------------------------------------------RLAGPDSELARALTHRLERRGIRVRRQLTLWLAGPA
AECPTVADLDAATHT-VLSTL--LDLIPSMGQGGG--RLLAVTEDVHGATTLCPAQALLTGLALALPEEFPRLTAYGVDLSSYDSL--GARLDALEREAF
APG-GGAVAWRAGRRLVRIPVAVATDAAP--ASSPLPPDGTYLITGGAGGLGAALARDLAGRGQPTLVLAGRSACPPNSL-----MTEL----DALGVTA
AYRVADVSVEADVEALVGDL-----PPLDGVFHAAGVVRPGTLRTKSLEEMAEVMAAKVRGSHLLSRAL-WRHPAVCVAFSSVTSVLPGLALGDYAAANA
FLDAFAASER-ATGRPWQSLNFAAFAETGLAAGAPSTVPAMTRGVAPLPPGAGLAALHAACGIDAAQLVVA-ETTAELSAEMTAEMTAEMTAESATVRPG
----AAVSGTAGLSEHVASATRRSGTS-VSVPPGDPSPTTAPGSPAPA---------PATGTADPAPAHITGVLCRLLAEALHRSPAEIGDQFLTMGLDS
LSAVDLVRRLESELGRALPPTLFFEYRTIGELATHLSTDQ----------
>tr|A0A060ZFR8|A0A060ZFR8_9ACTN Acyl transferase OS=Streptomyces iranensis GN=SIRAN1795 PE=4 SV=1
----------------------------------------------------------------RLVGPDSELARALAHRLERRGVTVRRQLTLWLAGPA
TECATVTDLDASTHT-VLTTL--RDLLPSMSQGSG--RLLAVTEDVHGATTLRPAQALLTGLALALPEEFPRLTAYGVDLSSYDSL--DTRLDALEREVL
APDVGGTVAWRAGRRLVRTPVAVAAGAPP--SSSPLPPDGTYLITGGTGGLGAALARDLAGRGQPTLVLAGRSARPPSSL-----MAEL----DALGATA
DYRVADVSAEADTEALVADL-----PPLDGVFHTAGVVRPGTMRTKSLEEMAEVLAAKVRGSHLLSRAL-WRHPAVCVAFSSVTSVLPGLALGDYAAANA
FLDAFAASER-AAGRPWQSLNFAAFAETGLAAGARSTAPATTRGVAPLTPGAGLAALHVACGIDAAQLVVA-E----------------LTAEPATVRPG
----AAVSGTARLPERVASAT----------------------GTAPA---------PATGTAAPAPAHITGVLRRLLAEALHRSPAEVGDQFLTMGLDS
LSAVDLVRRLESELGRALPPTLFFEYRTIGELAAHLSTDQ----------
>tr|A0A0Q7TR92|A0A0Q7TR92_9ACTN Non-ribosomal peptide synthetase OS=Streptomyces sp. Root55 GN=ASD51_22100 PE=4 SV=1
----------------------------------------------------------------LVTGPDPAAVDELGRRLADQGVGTTVQAVVLLAGPA
TGGTSA-DIERVQGE-LVSAF--NEALALLLTGAR--RLLVVTEDAHGHGRPDPVQAVLGGLALAVPSESAGVVANWVDLSSLDDA--GQRLRAVLAEAA
APQAAGAVAWRSGQRLVRTVAGEAADPGR--VLDRLPADGTFLITGGAGGLGSALARDLAGRGRPVLRLTGRSPHPPEGL-----LEEL----AALGADA
RYHRADLTSRDDVEKLVAAL-----PAPDAVFHAAGVVHPGSLRETKAEETTEALGAKTLGTVLLSEAL-RRHPGVCVAFSSVSSVLPGLALGAYAAANA
FLDSFAAAER-QAGRPWLSVNFGPFARTGLAAPLAAHTRDARDGDRPLATAPALAALRSACGGEATQWVLA-DRTPRPDRTVRPDRTSAQ----------
--------PRLPQVAHTSL------------A-------------------------SAAGDEVTSPSGTAAVLRELLAQSLGVPASSVDDSFLSLGLDS
LGAVDLVKRLERRTGRSLPATLFFEYRTVRELAARLDAEA----------
>tr|A0A0D6UR69|A0A0D6UR69_STRGR Uncharacterized protein OS=Streptomyces griseus GN=BF14_4129 PE=4 SV=1
----------------------------------------------------------------LLTGPDPASVDRLASHLSAAGVRRYEDAVVLVAGPA
PVQDTADTLGRVHDA-ALAAF--GEALARFETHAD--RLLVVTEDVHGTVRPRPAHAVLGGLLLALPQETPRAAATALDLCSLDTP--SQRLKAVLAELE
APGSTTIVAWRAGRRLTRRFVPSAAGSAS--TRSPLPPDGTFLITGGGGGIGAALARDLAGRGRPTLVLTGRSPALPVGL-----ADEL----RTLGATV
QYRVADVSVEGDVDALLAEL-----PRLDALFHAAGVVRPGTLRNRRAEETADSLAAKARGTLLLSLAL-RRHPAVRVAFSSVSAVVPGLALGDYAGANA
FLDAFAASER-HAGRPWQSVNLAALAGTGMAAALGTSTTVRNAGGRPVALAPALAALSTACGVDAAQLLLA-DLTPPSPSVAANS--PEA----------
--------PERP----TTTAEPS--------G-------------------------RTPAEGTGSGTNTSALLRRLLASALRLPATEVPDPFLALGLDS
LAAVDLVRQLERELGTTLPATLFFEYRTVAELAAHLDSTP----------
>tr|H0BG55|H0BG55_9ACTN Putative NRPS-type-I PKS fusion protein OS=Streptomyces sp. W007 GN=SPW_4240 PE=4 SV=1
----------------------------------------------------------------LLTGPDSAYVDRLASQLSAEGVRMHVDAVVLVAGPS
PGQDTADALGRAQDA-ALAAF--GEALARFEAGAD--RLLVLTEDVHGTVRPRPAHAVLGGLLLALPQETPGASATALDLCSLDTP--SQRLTAVLAELA
TPSGTAQVAWRAGRRLTRRFAPLTGGSGA--TPSPLPPDGTFLITGGGGGIGAALARDLAGPGRPTLVLAGRSPRPPAGL-----AEEL----RSLGATV
HYRVADVSVEGDVDALIAGL-----PRLDGLFHAAGAVRPGTLRNRVAEETADALAAKTRGSLLLSLAL-RRHPAVRVVFSSVSAVLPGLALGDYAGANA
FLDAFAASER-HAGRPWQSVNLAALAGTGMAAALGTSTTVRSPGGRPVALAPALAALRTACGVDAAQLLIA-DLTPSPESSVAAD--PIA----------
--------PAEAGTEPAAPDRSGSGTS-VSVS-------------------------RSSRAVTGPRTGTAALLRRLLASALSLPDTGIADPFLALGLDS
LAAVDLVRQLERELGRPLPATLFFEYRTIAELAAHLDTTP----------
>tr|A0A0R3RGQ9|A0A0R3RGQ9_9BILA Uncharacterized protein OS=Elaeophora elaphi PE=4 SV=1
---YEPCWVPCKLTT-RRRLPKGVLLFVPSTKAVDALIMLHNLFIPVQCIFSDALSTGNTNDKIYINSNKEESYHHLANFLRNTNFYYDTVIHAWNFSSY
ESGRIN-------DSYLLPSFYSIYWILTSIMQNDLRFLVIIDWNAIPEIF------TVLGPIRELTMTRQFVQAACLLCTLEVNLFEALQL---FESY-
QTDFSLIRNLIGEFEYFSY-----QLKSFEWNDCLIRSSDVVVIF-GFGNISQSFINVLCQNFDFTICIASPNATCHFEKNRWKSSRKFKISDTQEEHII
RAYDVDITKEDHLNELMLQY-----GRINIIIHAAAGKAASIKFAKSFDQMQFVLQPKIRGIRNVIDILYENRSFILNSSMNA--LFGLPGNSDYAASNI
FLDSC-CRGNFRNIENITSVQWSGWKDSNMLNT-----------------------------------YN-GNRSQNPVANLIIEHSLLVQEAE------
------------RMIWKCL--HERGLIAVSFSPNDIVHEIRKLNFNTNGKFVTVPEQESVKRN---CDDLRNIIAKIWMNYLGVEQITCHDDFFQLGGHS
LNGMQIIWEINRVMEIDCKLDDLFQNSQFENFLQFLQRLDV---------
>tr|J0DYR9|J0DYR9_LOALO Uncharacterized protein OS=Loa loa GN=LOAG_17563 PE=4 SV=1
---YESCWIPYKFTN-RRRLPKGILLFLPITKPINTLTILHNLFVPVRCIFSDTLSSGNINGNVYINSNNEESYQQLASFLRNGDFHYDTIIHAWNFPNH
ETERTN-------DSYLLSSFYSIYWILANVIQNDLRLLVSIDWDAEPELF------TVLGPIRELAMTKRSMKAACILCTPEVNLFEGLQL---LESY-
PADFLLIRNSIGEFEHFSY-----KLKPIEENDCLVQSADVVVIF-GFGNIGQSFVTVLCQNFDFTIYLVSPNATRHFQQNQWKTSRKFKMSVINDQHTI
HAYDVDITKKEDLTQIMSQH-----GRINVIIHAAAGKIDSTKFEKNFNEIQSIFQPKIRGIRNIIDTLHGNRSLILNSSMNA--LFGLPGNTDYAASNI
FLDACCCRRNFRNIQNITTIQWTGWKDSNMLGY-----------------------------------YMNENKSQNPVTDLIIEYSLSLEEAG------
------------QMIWKCF--HERGLIAVSSVPNDIIREIRKLNFMTSRKFGIIPEQKTVEKN---CNDLRNIIAKIWMDNLGVEQVTYHDDFFQLGGHS
LNGMQIIWEINRMLQINCKLDDLFQNSKFENFLKFLQKFVI---------
>tr|A0A0B2VT50|A0A0B2VT50_TOXCA Linear gramicidin synthase subunit B OS=Toxocara canis GN=lgrB PE=4 SV=1
---FRRCWIDIPKLL--ATTLKCVLLFLPLSNSLQQLVDFKNRFIKYICVQPNRNRD--CDDVLQINPAQEIGYQELANHLRMLRFQCSLVVHAWNVADF
EN-LSV-------DQKLEQSFYSVLWIKRYFSD-ALNIIAVVDDSAPAEVF------TILGPIRELHTTKPLSYGICLSVSCDADLCSLIHQL-HFSSW-
KPEFCYVRYDGNKLQEMNF-----CETVV-SNDYLLHDGDVVVVLGGCGSVGQAFVRFFCKKLKSTVILASRIATQRCEE-------TLQ--TFGGQHQF
VAYDVDLGNAKEIKQLLQKY-----SHIDLIVHAAGQAT-TTRLEKTREDVETVFASKIYGTRNLLSALDNNGGLIMTSSLSA--ILGIHGSEDYAAANI
FLDEVSNR--FCSIDKLISIEWCAWKSSTMIAG-----------------------------------YTS--S-YDEIAQLIKTNSLSDHECE------
------------RLFFDAL--QHTGCMAISTAPIVIVKEIERIQKRHSVVV---DS-VSQPIA---VSTIENITTQIWEECLGVKNISLQDNFFQLGGHS
LNALQITWQINKRLGFASTVNDLFKYPILGDFLAILQNKRK---------
>tr|A0A044S6I2|A0A044S6I2_ONCVO Uncharacterized protein OS=Onchocerca volvulus GN=WBGene00238648 PE=4 SV=1
---YEPCWIPCKFSTQKQQLPKGVLLFLPFTKSINALTMLHNLFIPVQCIFSDIVSSENVNENIYINSNKEESYQQLANYLHTINFHYDTIIHAWNLSNE
IFDRID-------NSFLFSSFYSIYWILANVTQNDLRFLVCIDWNSEPEIF------TVLGPIRELAMTGQLTQTACILCTSEVNLFEALQL---LESL-
QANFAFIRNSVNEFEHFSY-----QLKAIRKNDCLIRNADIIVIF-GFGNIGQSFINVLCQNFDFTIYVVSPNATRHFQENQWKVSRKSGKAFQSGNHTI
LAYDVDVTKEDELMQIMLQH-----GRINVIIHAAAAKIDNIKFEKSFDEIEFVLQPKVRGTRNIINTLHQNRNLILNSSMNA--LFGLPGNNDYAASNI
FLDAC-CRRNFRNIHNITTIQWTGWKASNMFNY-----------------------------------YSMENKSLNPVANLIVEYSLSVQDAE------
------------RMIWKCL--HEQGLIAVSSVPSDIAREIHKLNFTINRKFTNIPEGSQIEKN---STDLRNTVAKIWMNYLGVEQVTDQGDFIQLGGHS
LNGMQIIWEINRMMKINCKLDDLFKNSRFGNFLQFLQQLII---------
>tr|A0A0N5D2U7|A0A0N5D2U7_THECL Uncharacterized protein OS=Thelazia callipaeda PE=4 SV=1
---YQPCWVPINFTSQSIWNSKGVLIFAPPNKSINELVVLRNLFIPYFCVLNANLSSDSTDSNTYISDLTEKSYKQLADILCDQNFHFDTIIHAWNFCEN
AC-LYK-------EPTLLSSFYSIRWIIQNIVSTILRFLILIGQDSEAESY------TALNPIRELIMMQNSVHCTSLLCKSEVNLFKALQL---LESF-
QPDFSLIRNLVDQYEYFSY-----FLKLFH-QNCLIQNHDIIVIFGGFGRIGQSFLKVLCQNFKANIYSSSPNATRHFLQHEWQNGN------NCDEHKI
IANDVDISKYVELQNIIAKY-----GRIDVIIHAAASRNHPNVFEKNFSQIESILQPKINGTRNVLKVLSENRSLILNSSMNA--LFGLPGNSDYAASNS
FLDAL-CDQKFCNIQNITSIQWMGWKGSQMLEE-----------------------------------YAI--QTQNPVANLIMQNSILQDNAE------
------------ELILNCL--HERGLVAVSFVPNEIIKEFRKLNFRNSEKKKL----KDEEVN---CNDLKNFISKIWMDCLAVENITDSDDFFQLGGHS
LNGMQIIWEINRVTKINLKLDNLLKNSKFKDFLHYLQRINA---------
>tr|A0A0M3JX13|A0A0M3JX13_ANISI Uncharacterized protein OS=Anisakis simplex PE=4 SV=1
---FRRCWVGLQKLPSRSTPLKSVLLFMPMNGTLKQIIDLKNLFIECVHVEPIEAAVRNTNGILTIDPSQENAYQQLGDHLRRANFKCSLVIHAWNMRDF
EN-LSV-------AQRLYISFYSHLWIKRYLSDIHLSVISLVQARAPPEAL------TLLGPIRELHMTQLQSYALCLQISDGVDLCNHILHL-RQSIW-
KPKFCYLRCDANRLQEMSF-----CESVH-ADSHLFHENDLILIFGGCGSLGQAFIKFLTRQYRSTFVIVSRNARNIFGQ-------KIQ--SQDGGHCF
DVYDIDMSDAPKIRNLNEKY-----QRINVVINAAGQVT-SKQLHKSGRDVERVFASKIYGTRNIFDALQSNRGVLLTSTLSS--ILGINGNEDYAAANV
FLDELAEFSYRSVTDNVISVQWSGWKDSTMIAE-----------------------------------YAS--DANSQVAKLIIDNSLSDLQYE------
------------RVFFNAV--QYRGCNAVSTVPAEIVDQVARLQKQPLSFT---EPQIAATTH---LKLNEEMVKEIWKQCLGVETISMKDNFFHLGGHS
LNGMQITWQINKQLGHNFTINDLFKHPVLADFLELLSSNKN---------
>tr|G2NX71|G2NX71_STRVO Beta-ketoacyl synthase OS=Streptomyces violaceusniger Tu 4113 GN=Strvi_8003 PE=4 SV=1
GWRYRVSWKPVTERSAAGVLGGCWVVVVPVDGAGGVWRMLAGRGVDVRVVESDA-----------------ADRAGIADELRAADASVTGVVSLLAVGDA
S-----------V-TDVLRTAALVQALGDAGVGAPLWVATRGAVSGRSDGVVSPGQALVWGLGRVAALELPERWGGLVDLPESVDER---VLGRLAGVLA
GVGGEDQVAVRGSGVFGRRLVRAASSGSAASEGSWSPGAGSVLVTGGTGALGAYLARWLVENGAEHVVLTSRRGLDAPGA------VELRDELAASGARV
TVAACDVADRDALAELLAGLPE--ELPLTAVVHAAGVLDDGVLDSLTPERFASVLRAKADAARHLDELTRDLDLTAFVLFSSITGSVGAAGQGNYAAANA
YLDALAELRR-AEGLPATSIAWGPWAGSGMAGDDAMERRMRREGMPPMAPESAVAALRQALDVDDTAVVADIDWEN----------------------FT
RTLTAVRPSPLIAEAEAGPRAATGAESG---------KVVTDA-DSATP---LGERLSGLPKG-EQDRALLELVRTQVASVLGAEAVEAGRAFKELGFDS
LAAIELRNRLNAATGLRLAATLIYDYPNATALADHLRTE-----------
>tr|G4XIM8|G4XIM8_9ACTN Polyketide synthase type I OS=Nocardiopsis sp. FU40 GN=apoS6 PE=4 SV=1
GLEYTAAWRRGDEVFAE---AADAFGLHPALLDSALHTGVTLFASSALRVQAPV-----------------ASGFA-----LRPLEISDRDTVLLECVSA
--------------AANSEVLRSVQSASARFADSRLVVVTRGAVADPAEDVPDLAAAAVWGLLRSAQAEHPGRFVL-LDLDRGDASY-----RAVPA---
-ASDEPQLAVRDGEVRVPRLARVASPDLAVPSPAFSS-DRTVLVTGATGGLGRLIARHLVTHGVRHLLLASRRGMAAPGA------DELAAELGRWGARV
TMAACDVANPDEVARLLAAVPE--DHPLGAVVHAAGALDDGVLEALDPSRMAAVSRPKADAAWNLHTFTRDL--DAFVLFSSAAGTLGSPGQGNYAAANA
FLDALAQHRR-AQGLPAVSLAWGAWAE-GMSEDASGRARLVRGGMRPLSEQDGLALFDAALGSDRAVLPMALDLGA----------------------VL
RESGGTVP-AVFRG-----RTPV---RR---------T-ARSA-GSGTP---LAGRLAGLSAD-EQDRAMRTLVREQVARVLGAEHVELAKAFQDMGFDS
LTALELRNRLNEATGLRLNATLIFDYPTPLTLAQHLREQ-----------
>tr|C5HV18|C5HV18_STRAT Polyketide synthase OS=Streptomyces antibioticus GN=idmP PE=4 SV=1
SWRYRVGWRPAQIS---TTPTGTWLVIAPAAHQEHPWESLRDGGAEVRTVVDPT-----------------ALQDSLAQEL---GAQIDGVLSLLALDET
P-----------LPAGLGATLTLLQALGDAGIEAPLWCATQGAVSSGVDHLTRPLQAQVWGLGRVAGLEHPDRWGGLVDLPETVDAR---SAGRLRALLA
EPGDEDQLALRPSGAFVRRLTRAPLEDTP-PVREWRP-DGTTLITGGTGGLGGHVARWLAAQGAGHLVLTSRRGPDADGA------AELREELQGMGSRV
SIVACDASDRNALGALLRRLRDE-GTPVRAVVHTAGVAGRFTLADADLADLAETLGAKAGGAAALDELLAGGEPDAFVLFSSNAGVWGGAGQGPYAAANA
YLDALAEQRR-ARGAAATSVAWGMWSGQGLVAQPGVEEALRRLGLKAMDPDLAITALHQALDRDETTLVTDMDWDR----------------------FV
SVFTAARPRPLLDEAARILRAAEAG-------------HEANS-ESRSA---LAEQLAGLAPA-EQHRLLVEMVRAQAATVLGGDAVDQDRQFQELGFNS
VSAVELRNRLNEATGLRLPASLVFDHPTPAALARRIRAE-----------
>tr|X5IBU4|X5IBU4_9ACTN Type I polyketide synthase OS=Streptomyces sp. MJ635-86F5 GN=cmiP5 PE=4 SV=1
GWRYRSTWKPLSDGAMGDLAGDRWMVVHASGAADAEPRALAARGAHVVAVETAA-----------------TDRG----HLTARGAPIAGVVSLLAFAEG
A-----------QPAALAQTLLLIQALGDAEVGAPLWLVTRGAVAVSSDE-ADPVQAQIWGLGRAAALEHSRRWGGMIDLPTTLGER---TAARLAAVLT
RDHGEDQVAVREAGVLGRRLVRAARDD--VRATPWRP-RGTVLITGGTGALGGHVARRLARNGAGHLVLTGRRGLGAPGA------ADLRDELVASGAEV
TIASCDAGDRSQLAQLVRSLADR-GNPVRAVVHAAGVDSARELSLMALDELADTLRAKAGGAAHLDALF-DDDLDAFVLFSSVAGIWGGAGQGAYAAANA
SLDALAERRR-GRGLAATAVAWGPWAEAGMAAQGDDEELLRRQGLPPMEPDHAVTALERAVAEGVATVVADVAWNR----------------------FA
AGFTAGRPSPLIGDVQQTLAGTPDAQFG-------------DV-PAATE---IGRRLAGLDPA-EQHSVVLELVCRQAALVLGPDAIETGRAFRDLGFDS
LSAVELRNRLAESTGLRLPTTMVFDYPTPVGLADRLLAE-----------
>tr|J1RVE2|J1RVE2_9ACTN Acyl transferase (Fragment) OS=Streptomyces auratus AGR0001 GN=SU9_33608 PE=4 SV=1
SWRYRITWKPVPAGAAPATLRGTWLVVTGGAHTP---TALSAAGAHPVLVPDAE-----------------ADRTALAGTIDAALPPVAGVVSLLALDED
E-----------HHRGFAATVALVQALDDTGVEAPLWFATRGAVADPQRGVTAPRQALVWGFGRVVALEQPERWGGLLDLPETLDPA---AATAVVRALA
GIGDEDQLAIRPHGVLARRLVRAATGELD-TTRRWTP-QGTVLVTGGTGALGRHVARWLAQNGAAHLLLVSRRGAETPGT------DELAAELAEFGTHT
EFAACDIADRDALADLLDTIPA--DRPLTAVLHTAAVLDDATINSLTPAQLAGVLRVKAGGARNLDELTRPRGLSAFVLFSSTAGTIGAPGHANYAPGNA
YLDALAQQRR-AAGHRATSIAWGPWAEAGMAEGT-VGERLHRHGVRVMDPRSAVAALQRALDHDDTTLVTDIDWDT----------------------FT
HAYTTARPRPLIADAQRARATAAP--------------ATEET-TEGPA---LARRLAALGEA-EQRQALSELVRAHVAAVLNPDEVAPHRAFRELGFDS
LMAVELRNALSTAIGTRLPATLIFDHPTPAALATRLRTE-----------
>tr|R1HJ52|R1HJ52_9PSEU Beta-ketoacyl synthase (Fragment) OS=Amycolatopsis vancoresmycina DSM 44592 GN=H480_36228 PE=4 SV=1
AWRYRVEWKPLAEPEA-VTLSGRWAVVAPAGTDTTELSCLTAAGAEPVVLEPGG-----------------GLTAELANGLADSLPAVAGVISLLPD---
----------------APGTLLLTQALD--GSTAPLWLLTRNAVALPGDTPPAADPAQVWALGRVVGLEHPERWGGLVDLPATLDRR---ATRRLAAVLA
GLDHEDQVALRASGLFARRLAHAPGAE---PRRNWRP-RGTVLVTGGTGALGRHVARWLARAGAEHLVLVSRRGADAPGA------AELEAE---LGTRV
TFAACDLADRDAVAALVERLGD-----VRAVVHTAGLPQAQTIDGTSVADFAEILAAKAAGADHLDELLGD-DLDAFVLFSSNAGVWGSAGQGAYAAANA
HLDALAARRR-AAGRPATAVAWGSWAGDGMAGSAEAKEHLRRRGLREMAPERAIAALQQALDADETFVVADMDWAR----------------------FA
AGFTAARRRPLIEDVRAGEEVV--------------------T-EVGTG---LAEAVRGLGPR-EAAHHVLELVRAQAAAVLGGAAVPADRAFRDLGFDS
LTAVELRNRLTAATGVRLPSTVVFDHPHPRALAGLLLDE-----------
>tr|R1G5I0|R1G5I0_9PSEU Beta-ketoacyl synthase (Fragment) OS=Amycolatopsis vancoresmycina DSM 44592 GN=H480_20135 PE=4 SV=1
GVDYRAVWTRGSDVFAELRGEAARFGLHPALLDAALHSGVSLAASTVLRVATPV-----------------SADVA-----LRT------FEVFR--VPD
--------------GSVTAVLARLQEGGP---DGLLVVHTTGAV-ADGEDVTDLAAAAVTGLVRSAQTENPGRFVL-LDAGEVP------------A---
-PLGEPQLALRSGTWRAPRLARASIVD----NTPDWG-DGAVLITGASGLLGGLVARHLVTHGVRRLLLLSRREPA-----------DLAHELAGLGATA
TAVACDVADRARLAEVLA------GHHVSAVVHAAGVLDDGVLESLTPDRLAAVLRPKAEAALNLHELTTDL--SAFVLFSSFAATTGGAGQAGYAAANA
FLDALAQHRR-AHGLPAVALAWGLWAEASMGHADGDRRRMAGAGMTPLDTEFGLALFDRAVAADRAVLPVRLELAA----------------------LR
RQP--VTP-TLFHG-----PPAR---RQ-----------ATAA-AAQTS---FADRLAALGED-DRVRQVLDLVRELVAGVLGGAAVEPARAFKELGFDS
LTALELRNRLAAETGLRLPATLVFDHPTPQALTRYVVER-----------
>tr|A0A0D5EEP5|A0A0D5EEP5_9BURK Methyltransferase domain protein OS=Burkholderia ubonensis MSMB22 GN=BW23_5791 PE=4 SV=1
GML-REVTEPQAWLD--FGLTPGWWSFTDPLLDAAQWPALATPEAESVIVAKA------------------------AARAESGRAPLERVTEIYAWRAA
A-----------DP---REPLALCQALP-RWRELQASFVTAGAQP--AGGVTEPLQALLWGHLPAFVNEN-ARFARIVDVDRDEP-V---GPALLGAL--
-QRDECQIAVRRDAWFVPRLRAATLVE---AGAPVVSGDASYLITGGFGALGIETARALAAQGARHLLLLGRRVPASAEA--------ALAGLREQGVAV
HALVADVGDETALRAALASVPPE-APPLRGVVHSVGVLDDGVVGQQSWERYLRVLRPKMAGALLLHRLLDARALDFFVLYSSAAGLMGNPGQANHAAASA
FLDAFAWYLR-GQGVPAVALDWGAWSEIGAA-ARDVGARLGAEGAGVIAPEQGAAVIARQFGCANTQLVLPLNLRQ----------------------PV
DASRQPQVRRLLAEDAAAAGMRAVDAGD---------GEGEAA-EAGDA---WLARLLRMSVR-ERRRHLGDYLAQTAGALLKPGAIDAQASLFDQGLDS
LLAIDLRGTLERRFGQRFESTLLFDQPSVAALTDFLLGA-----------
>tr|Q0B308|Q0B308_BURCM Beta-ketoacyl synthase OS=Burkholderia ambifaria (strain ATCC BAA-244 / AMMD) GN=Bamb_5920 PE=4 SV=1
GML-REVTEPQAWLD--FGLTPGWWGFADPLLDAAQWPALATAEAESVIVART------------------------AASADSGRAPLERVDELYAWRPT
V-----------DP---REPLALCQALP-RWRQLEASFLTAGAQA--AGRVSEPLQALLWGHLPAFVNEN-ARFARIIDVDRDEP-A---GAALLGAL--
-QREDCQIAVRGEAGFVPRLRRAALVE---AGAPVVSAEASYLVTGGFGALGIETARALAAQGARHLLLLGRRLPPSAEV--------ALAGLREQGVAV
HTLLADVGDEASLRAALAGVPAE-LPPLRGVVHSVGVLDDGVIGQQSWARYQRVLHPKLGGALLLHRLLAPRPLDFFVLYSSAAGLMGNPGQANHAAASA
FLDAFAWYLR-GRGVPAVALDWGAWSEIGAA-ARDVGARLGAEGAGVIAPEQGAAVMARQFGCANTQLVLPLKLNQ----------------------PI
DASRQPQVRRLLAEEAAGGATQATGVTG---------GAAADA-EAGDA---WLDRLLRVSTR-ERRRELGEYLEQTAGSLLRPGAIDGQASLFDQGLDS
LLAIDLRGTLERRFEQRFESTLLFDHPSVAALTEFLLGA-----------
>tr|A0A0A8EKB8|A0A0A8EKB8_9ACTN Acyl transferase OS=Streptomyces sp. 769 GN=GZL_03712 PE=4 SV=1
SWWYRVVWRPAAEPAA-AALTGSWLVLVPAALAEDELAALTGHGAEVVLLPADT-----------------D--ADLTERLRTVDGAPNGVLSLLSRDGR
L-----------WP-----NVVAAQALGEAKVDAPLWCVTQDAVAGRSDRLRNADQAQIWGFGRVFGLEHPQRWGGLVDLPELVDDR---TLARLVGVLA
RRGGEDQFAVREGGVFARRLEHAGG----RAAQSWQP-RGTVLITGGTGALGTELARWLAANGAEHLVLAGRRGPDAPGA------AELAAE---LGDQV
TIAACDVADRTALAALLGSIPA--ERPLTAVVHAAGVLDDGLLTALTPDRVEAVLRPKVDAARALHELTADLELDAFVLCSSVAGVWGNGGQAAYAAANA
FLDALAQQRR-AAGLPATSIALGLLAGGGLAEAG--EQHQRRLGLRPMAPGTVASALAQAVCRNESALLADVDWST----------------------FV
PAMGAVRPLSLVDEARMLPAA------------------------EKVE---LRDWLEGLSEA-EQQRLLLELVRSQVAAVLGSQGIDASRAFRELGFDS
LTGVDFRNRLGAATGLTLPATLVFDHPTPMVLVDFLRGE-----------
>sp|Q03133|ERYA3_SACER Erythronolide synthase, modules 5 and 6 OS=Saccharopolyspora erythraea GN=eryA PE=1 SV=4
DWRYQVVWREAEWESA--SLAGRVLLVTGP-GVPSELSGLEQSGATVLTCDESR-----------------ST---IGTAL---TDALSTVGVAAVPHGE
A-----------V-DPSLDALALVQALGAAGVEAPLWVLTRNAVQADG-ELVDPAQAMVGGLGRVVGIEQPGRWGGLVDLVDA-DAA---SIRSLAAVLA
DPRGEEQVAIRADGIKVARLVPAPARA---RTHPLEPLAGTVLVTGGTGGIGAHLARWLARSGAEHLVLLGRRGADAPGA------SELREELTALGTGV
TIAACDVADRARLEAVLAAAAAE-GRTVSAVMHAAGVSTSTPLDDLTEAEFTEIADVKVRGTVNLDELCP--DLDAFVLFSSNAGVWGSPGLASYAAANA
FLDGFARAAR-SEGAPVTSIAWGLWAGQNMAGEG--GEYLRSQGLRAMDPDRAVEELHITLDHGQTSVVVDMDRRR----------------------FV
ELFTAARHRPLFDEARAEARQ---------------------S-EEGPA---LAQRLAALLDG-REREHLAHLIRAEVAAVLGDAAIDRDRAFRDLGFDS
MTAVDLRNRLAAVTGVREAATVVFDHPTITRLADHYLER-----------
>tr|A0A060ZVD9|A0A060ZVD9_9ACTN Type I polyketide synthase OS=Streptomyces iranensis GN=SIRAN6351 PE=4 SV=1
GWRYRVTWKPLPDGQ-PARLTGAWLVVAPD--TEDTWGVLAERGADVRRIADTA-----------------ADGDELAERLRAAGIPFTGVLSLLALDGR
S-----------HPAGVAAQLALVQALGDAEVGAPLWSATQGAVSGRADPLDSPEQALVWGLGRVAALEHGERWGGLVDLPGAPDER---ALARLVTVLA
GAEEEDQVAIRATGLLVRRLVRAPLAATP-AVRAWKP-TGTTLVTGGTGALGAHVARWLAGNGAEHLVLTSRRGLDAPGA------ADLRSELTELGAKV
TIAACDVADRAQVEALLADIPA--EHPLTAVVHTAAVLDDGVIEGLTPDQVDRVLKVKVDATRHLHELTRDLDLSAFVLFSSFAATFGAPGQGNYAPGNA
FLDAFAEHRR-AQGLPATSLAWGPWGEGGMAEGG-VGDRMRRHGVIEMAPRAAVTALQHALDRDESVLVVDMEWKR----------------------FV
LAFTSGRSRPLLHDARDVIQDM----AG---------EVEADG-AGAVA---LAQQLAGVPEA-EQERLVLELVRTAVAAVLGADDVEAGRAFKELGFDS
LTAVELRNRLSAASGLKLPPTLIFDYPTPTVLARQLRTE-----------
>tr|K7QQB6|K7QQB6_9ACTN PyrA5 OS=Streptomyces rugosporus GN=pyrA5 PE=4 SV=1
GYEYRAVWRSEGVLFAEVADAGGF-AVHPALLDGALHSAVSVHGPPVLRVREPE-----------------GA-V------TRPQVSVTAVTILLPCESS
A-----------DPERAEHVLAVVQEADERYADTTLAVVTRGAVAGEEDVLD-LPHAPIWGLIRVAQAENPGRLV-LIDLDTSRDAA---GLALN-AAL-
-ASGEPQLAIRKGVLHAPRLTRVRPTSSP-SPLELDE-DGVVLVTGGTGLLGGLVAEHLASYGMRHVLRLGRAGG------------------------E
GAVACDVSDRQAVQELLAS---L-DRPVTAVVHCAGLLDDATVQNLTPEAVRTVFAPKVDGAWHLHELVG--GTAAFVLFSSAAGTLGNPGQANYAAANT
FLDALAAHRR-AQGRPAVSLAWGPWEGGLTDKTEADRARVRHNWITPFTAETGLAAFDTAFDTA----------------------------------FN
GGF-NGVLVPLRLDIRAAATIHPMLRES---------GQKPPA-SGRDA---LIRELSGRAVP-EQEHLVLELVRERTAAVLGGAAVDPQRPFRELGFDS
LTAVDLRNQLGAATGLRLPATLIFDYPTAALLAAHLRTE-----------
>tr|H0KBG1|H0KBG1_9PSEU Beta-ketoacyl synthase (Fragment) OS=Saccharomonospora azurea SZMC 14600 GN=SZMC14600_22378 PE=4 SV=1
GLEYRAAWRLGDDVYTEEHAEAERCGLHPALLDAALHSGVTIVAALRVRVRTSV-----------------GTDVS-----LRA------ITVFE--AAG
--------------SDPSTVLDRVQDADSSDGDARLVVVTRGAVAEPGEPVRDVPAAGVWGLVRSVQAEHPDRVVI-VDVDDDPRST-----DLLGA---
-ASGEPQAAVRGGEVFVARLGRASAQLVASLPQPLNP-DGTVLITGGTGSLGGLVARRLV-QGVRRLVLLSRRGVASPEL------LESLA-----PAEV
SVVACDAADREALSGVIA---G--IETLTAVVHTAGVLDDGVVESMTAQRIETVMAPKALAAWNLHELTRDHDVAEFVLFSSASGVFGNAGQANYSAANT
FLDGLAAHRR-ALGLPGLSLAWGLWDQQGMAGADTDKARTSRSGSSALRPDQGLALFEATRKRPDAVLPAPLDPTA----------------------LR
---DDTVP-PLLRA-----QRSL---RR---------AASRKA-GGDGS---LAHKLAGLPVA-EQDKQLTDLVRANAAIVLGPERIEPRQAFKDLGFDS
LTSVELRNRLAAAVGTKLPATLIFDYPNPDALGTYLRTE-----------
>tr|D8MZG8|D8MZG8_RALSL RhiD polyketide synthase, rhizoxin biosynthesis OS=Ralstonia solanacearum GN=rhiD PE=4 SV=1
----------------------------------------------------------------------------------------------------
----------DSREQGVLALFRLVKLQLGYQQRALEVQIFTASVAVAGEPL-APEQAACHGLAGALAKECEHWRVELIDLPAD--A-QPLPVAM------
-TLPGECLAWRDGEWFAQRLLPLAERAT-------YREGGVYVVIGGAGGIGEVWTRHMIRHCRAVI-WLGRRAAD-------DEINGKLAALARIGPAP
LYIQADATDAEQLTRARRQVIER-FGPIHGLVHSALVLDDGRLAQMDEAQFSACLDAKTATSVRMAQVFAPDALDFVLFFSSMNAFSRAAGQGNYAAGCT
FADAFAAQDQ-HWPCAVKVINWGYWGSVGVV--PGHRARMAEQGLGSIEPDEGMAALDRLLAGPWPQGLVKLLMDRLLLALVFACLGELAGGGPLTEQRI
ADGDLRAQLQLVETCCRALPAILRGEQQATGVVAR--REIGAGTGGTAGLIDRLQGLYPE---DALSGQCRLLITDVLSKLIAPERLQRDVAFDRYGIDS
ILQISLIQALEKATG-ELSRTILFEYNTINQLTDYLLTE-----------
>tr|A0A080UG74|A0A080UG74_BACIU Polyketide synthase PksM OS=Bacillus subtilis subsp. niger GN=pksM PE=4 SV=1
----------------------------------------------------------------------------------------------------
----------EDQEKNVLHVFKIVKLQSGYGDKDVTWSVTVQAQPVQHESI-NPSHASIHGFAGTMAKEYPNWKIRLLDLEED--C-VWPIKQMF-----
-DRHGHAWAYRNQQWHQQELIPFQHSP--------YKTGGVYVVIGGAGYIGEAWSEYMIRSYQAII-WIGRSPLN-------DAIQAKLDRLANVGPMP
HYIAADAADVNSLQQAYEKVKER-YAHIHGVVHSAMNLSEQSLENMRLEEFRSGLSAKVDVSVCMAQVFER-DLDFVLFFSSLVAYIKNVKQSHYASGCA
FADAFAYRSQ-NWTCPVKVMNWGYWGNSEAA--ENFVQLMDQIGLGLIEPEAGMNALQALLSGPVSQAFIHTTLDDFLYRLL--LGQLQTAGLFKGGRLS
ADSNTKAMVVLAESMLKALPDILAGKVPATDVYLEERLEIGAGTGGSAGIFQKLKGLYPQTKDSALQEKSTEYMKKLIGETIPAGKIDSSEPLEKYGIDS
IVVVQLTNTLRKVLD-HVSSTLFFEYQTIDALVAHLIKT-----------
>tr|A0A0L6JGW4|A0A0L6JGW4_9FIRM 6-deoxyerythronolide-B synthase, Phenylalanine racemase (ATP-hydrolyzing) OS=Pseudobacteroides cellulosolvens ATCC 35603 = DSM 2933 GN=Bccel_0225 PE=4 SV=1
------------------------------------VKRLRQCRKDIIEVKLGEGFQSLNDGNFIID-GSLESFKRLLSKLKDRNIS--QVIHLCTAQGS
VEIKDVIEIDESQKKGVYNLLYLSQAISSREEPIDLVVISEKVYEITGMEQIYPQNATLFGLGKVVRLENPMLKCRCIDIDRE-T--GI---DTILIEIN
YPSDEYLTAYRNGDRYTQEIGHADLSRLDD-DEIEVKNDGVYIITGGTGRLGLKIAQWLASQNKVNIALLNRTHFPRVDPELCQRIEAIQKI-ESTGTAI
TLCSTDVTEITELNSTLSKLRECYGK-INGIIHCAGIGVGILLKDEQRETFENILAPKVYGTWLLENLTKDDNPDFLILFSSAITITGGVGAGSYTTANT
YLDSFVLKAK-KYFKKVLSINWTTWESVLRFAGVKID---KDRLIFKIPDDTALKAFDI-------VVHKK--INNVIIGEMNI--GSSIFDIKPYMPFT
LSQDT--------------QS--------------EIKQNRT-QIKLDSFSDALPELTGKAENE-SYTEMEDRIARVWGKVLGIGEINIYDSFFDLGGHS
VLAVKLEVEM-GKAGMPVEGADIYKYQTIKDMASYLGTK-----------
>tr|A0A0F7C1N4|A0A0F7C1N4_BRELA Polyketide synthase OS=Brevibacillus laterosporus GN=EX87_21220 PE=4 SV=1
------------------KDMGTVLIFKDETSIGEQMMQAFDSMGPWIQVEWGAEFEELDQRTYKIN-GLQTDYMTLIGLLKERGI--TQIVHLLSVMEK
QDVNDLVDLEETQKRGYESLVRLTKALLEHNDEIEILLVAPYVYELNEQQEIQPHHATLFGLGKVVTQEYPHLLCRAIDIDKW------TTAETILAELG
SKDKDYLVMHRKDQRFVEEFCEWNLDDIA-DDAIEIRENGVYLLTGGLGAIGLEMANYLASQASVNLVLINRSSLPSREEKSQRQITAI-RQIEALGSHV
TVLSADSSDQDELQAVLAQV-RSQFTTINGIIHSAGVAGEGFILRKEEASSQAVLSPKVKGTWLLDHLTKGDQLDFMVLFSSINSLYGGVGQGDYAAANA
YLDAFTSYRN-RHSGKTLTINWAAWKEVGMAVEY---GANHDVGFFSLSAIQAFQQVLHKQLK------------RVTIA-----------------EIN
YDNTS---EHL-----DALSFNLANPIKTKLAKMGRLKDRRQGAVPSQGLPD-IMLLGRNAG--ESYSANERLLAQVFCLELGLDEINIYDDFFSLGGDS
IIAVKIVNSVQKYLNKNIGISEIFQN------------------------
>tr|A0A0M8VN55|A0A0M8VN55_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. AS58 GN=ADL00_12465 PE=4 SV=1
-------------------------------------------GEQVVTVTAGTAYERTAEDAFLMRPEAAEDYEQLVDALQKDGPRTWNVLYLWDVKAD
------ASLEQAQARSLDGLVLLARAVGP-RRGSDATRLAVVTRGLAPVAGAPSAQALALGPVRTLPLEYPALTASVIDFEAAEDGTEDDFAAALLAEVY
AGLPDSLVAYRGSVRHVERVEQVP--TGSSWAQSRFRRGGVYLVTGGFGGVGTEIAGWLARNHQARLVLAGLTERWALEDEIRRRLALIRRL-ESAGAEV
HVECFDVTDREAVAQALGRAEARFG-PVEGVIHAAGVAGGALAQFQRSETMRQVLAPKLDGTLALAAALREHRLAFFAVFSSVSALLGNVGQVDYCAANA
YLDSWACSPE--APEDAVTIAWDTWRGVGMAAPERLPAAV-----------------VAA--------HADQEWSGIPAA--------------------
--AALAVFEQA----------VSGGQRRV--------LVSTDTLPDRLAARRRPEPAGPGTPVERSRAEVEETLIDIWRNLFGRSEIDVDANFFELGGDS
LLVVEAGRQIKERLQTTLPVSDLFKYPTVAHLVDRLSSDP----------
>tr|A0A0P1BFA4|A0A0P1BFA4_9BASI Polyketide synthase OS=Ceraceosorus bombacis PE=4 SV=1
----------------------------------------------------------------------------------------QALICAWPLGVI
DVSPES-----AMDHVDLISARLLSLMKALVNQTSAWSAVVITRDALHGHVSGVISSTLHGMVSGFAGRTTCVALDTSALLRP------AQIASATEEIL
ALSAFRYEIVDGVVRR---LAPSL-DKYPAQIQHRLPSEGTWVITGASGTIMTAILPWLVTSQRQQVAIFGRRKRDPDY---LADVRKR----LPAGVQV
HYETVDLHSSSSVSNAMNRLPG----TVKGIVHAAGVTRPALVRGQSREAYDEVFAPKVKGAWNLHQHAPS-TLEHFVLFSTFATVNVFPAMTNYIAANF
FLNSLASFRR-TQGLPAMAIGFGSWPGSPMLDGLSPALNA---ECPPLVDTKAYREIEKLMLMQRPPAKYRLDPQHLLDSLASQRSASSPRLPA-AASTS
DDITG-ALAELPAS----LMQSDSA--AVQATPSPPAPPASNGFSTSVFPSRLLEASELEAAPGAEARHVTRDIRELVLHIFAREEFRDDQRLETYGWDS
LYHLELTSQVKEKLGIELPESLDTGMATLQEICAAAAEA-----------
>tr|A0A0F0HJ91|A0A0F0HJ91_9PSEU Uncharacterized protein (Fragment) OS=Saccharothrix sp. ST-888 GN=UK12_32200 PE=4 SV=1
------------------------------------TGRLRESGEQVVTVTAGTDYERTAQDAFRVRPEIAGDFEQLVDALEEQGGRTWNVLYLWNVEAG
A-SLE-----QARVRSLDGLVLLARAVGP-RRGADATRLAVVTRGLAEEEPAPAEQALVLGPVRTLPLEYPALTASVIDFEAAADGAEDGFEQSVVTEVR
AALPDSLVAYRSAVRHIEHVEQLPTAS--AAAQTRFRQGAVYLVTGGFGGIGTEIAGWLARNYQARLVLTGRTPLPPTEAEIRRRLALVRR-LESAGAEV
HVECFDVTDREALAQALGRAEARFG-PIEGVVHAAGLAGGGLAQFQQSEAMRQVLAPKLDGTLALASALREHRLAFFAVFSSVSALLGSVGQVDYCAANA
FLDTWACSPEAPE--GAVTIAWDTWRGVGMAAPERLPAAV-----------------VA--------AHADHERSGIPAALAVFEQAVSGGQRRVVVSTG
T-----------------LPDRLAARGTRHLEPT-----------------------RHDTPVERSRAEVEQTLIEIWRNLFGRSEIDVDANFFELGGDS
LLVIEAGRQIKERLQTALPVSDLFKYPTVAHLVDRLSPD-----------
>tr|A0A097I358|A0A097I358_9DELT GulA OS=Pyxidicoccus fallax GN=gulA PE=4 SV=1
---YRLTWEEAPSPEVGASLARRWLVFADDQGVAEAAAGLLSSAHAVHRLHPADAFRRDG-NDFHIRPNEPEDYRAVLQALLSRGALPLGVLHLWNLRLP
EGATAVPDLREMAKLGNLSLTHLLKALDG--AGSAPPRVWIGAWALPGSE-QGLAQSAVWGLTRAIAQEHPALWGGIIDLDPLEAP--RLQAERLVTEVS
VPQPADRILYRQGRRQVSRLVRDTAPVSA--ATATFRGDRGYLITGGLGELGTRLAAWMVARGARHLILAGRKALPARRTWKQDGIDAVL-HLERLGAHV
HTPALDVGDGAALAAFLAGYEQEARPPIAGVAHLAGVIRPELLARLREESLEESFQSKVYGAWNLHQAFSGRGLDFFTLFSSASAVLNSPLLGSYAAANA
FLDGLAHFRR-ARGEPAQSLNWGFWSEAGMAA-----RDLHFD--ASASGQQGMRSFSPAVGLD---IFGGL-LSRDPVQSVVM-----------DVDWK
------LWLEAYPAAASPLLRTLRASEGVA-------AGSEQAAPAEEASRSL-----RDLPAEERRKAVEGILLTELSAVLKMAKISRTALFGSMGLDS
MLSLELRNRLERRTGLTLPGT-----------------------------
>tr|X0MS98|X0MS98_STRA9 Beta-ketoacyl synthase OS=Streptomyces albulus PD-1 GN=P354_27885 PE=4 SV=1
--FYRPVWHDAPAPRAGRADRAPLLVLTDRAGTAAELAAAGGWRQ-AVEVLPGAGFERRAADRYVLDPAEPEHYRRLLRELAADSRAGLDVAHLWSTEAP
DGGPQHRRREEVFGRGLGSVLHLVRAVTDAGVDGRVRCLYLHSGRGAAGVP-E--HEAVAGLALSTARHAPGIELFTVR--HDPARDGALPAAVLAAELT
ADGALREVRYEAGRRSVRTVERAPRPATPADGAAPLVEGGAYLITGGAGGVGRLLARYLAARYRARLVLLGRSPLPE------AVRAEL----EELGAQV
LGVRADVADAGQLRAALIEARGRF-GGLDGVFHLAGVADRVPLTEVDDAGFRRALAAKVQGVVNLDVLTRADRLGVFAAFSSVSALCGDFGAGSYAAANR
FLDAYLAVRRVASGERTLSLDWPLWDAGGVDALVELDTYQEATGLLRMTPRQALDAFDRAWQFDAPVLVPVLDPERIARTLGGAAVPPAATRA------G
----ASTEP----APAARLTPPAAHPAPPA-----------AAPTDA----------------ERYLPAVVDRLRRTLSGVLKLSAAQIDSQLDQYGIDS
VMIMEVNSLLGRDFT-GLRGTLLFEYRTVQDLAGYLV-------------
>tr|H0K8N7|H0K8N7_9PSEU Beta-ketoacyl synthase (Fragment) OS=Saccharomonospora azurea SZMC 14600 GN=SZMC14600_17385 PE=4 SV=1
--CYVPDWRSAAPGPQGSR-GDVLVIFSREPSSAARLGRLGGWPR-TIVVCDRTAAAEAPGDIHVIDPVDANAYRDLIAGLP--ATANVDVVHMWTTPHP
EVGDL----DEEIGRGAVSLLLLAQAVRASGRAGRTRCVSLHRDEDAADVP-A--HELIGGLASTAARHLPHLELCTVH--VPSTAGVEWLADVLRGELS
AVTSPRDVRYDGARRTVRTVRRLTGD---PAAAAPPTDGGVYVLAGGRGGVGMQLARHLARTYHARLVLLGRSAPPE------HACAEL----ESLGAEV
LAVRADLTDAHQTRAALVEARGRF-GHLDGVFHLAGVADQQPLTDVSGERFRSALAAKVHGVVNLDRCTRADRLSFFVAFSSVSSLIGDFGSGSYAAANR
FVDAYVRRRWAADGLRSVSVQWPLWEAGGMDSLVELTAYRETTGLDRLSPEQAMRALDVVWRYDVPVLAPVHDQELIARVLTGEESAV------------
-------------SEPERLTQHPSAPVAPS---------------PV----------------GTRTAELVDYLRNQASGVLKLDPAQIAGPLQEYGIDS
VMITELTDAVSDAFP-GLRGTVLFEYRTLADLAGYLL-------------
>tr|B2WW47|B2WW47_9ACTN PKS OS=Streptomyces albus GN=ozmN PE=1 SV=1
--FYEQVWRDEDVVAGAAPGSDAVLVLGDGDEVARGLAGRTGVRR-VVDVRAAAGFARTGPDRYAVDPECPGDFERLLAELARDGVRSLDVVHLWGLTAE
PVGYGEAALDGAFARGLHSLRSLALALHAVRHPGRVRCAYVLADPERGPRP-D--QEAVAGFALSLTGVLPRFELFTVA--CA---DGLDLPGLLAAELT
QGGRPAEIRHAATGRQVRVLRRAEET--RTAAAVPLKRGGTYLITGGTGGIGLELARHLAATYAARLVLISRSAGRPPA---REAADGL----AALGAEV
LLVAADTADPSGMRAAVARAKERF-GHLDGVFHLAGAADQCSLLDAEAARFTGLLSVKAHGVRLLDALTADEPLDLFVVFSSIASVVGDFGACAYAAANR
FLDSYAEERRVREGRRTLSAAWPLWRIGGVDALMERTGYRHRTGMREFTGEEGLRALDLAWRTGLVRLVPAVDPDTVDAALLPRPAAGARADS------G
----AATAATRETAVPASAVPHAAGPVAVTAVT-----RTNGAAVPA----------------SALLDRMRDHVRALLGQVLGLSVERIDDALDAYGLDS
VLVMETNEHLDRDFP-GARGTLLFEYRTVHDLAAHLL-------------
>tr|A0A0C5VQN4|A0A0C5VQN4_9GAMM Polyketide synthase modules-related protein OS=Gynuella sunshinyii YC6258 GN=YC6258_03672 PE=4 SV=1
--------------------------------------------------SPTVAMPATDHSIIVLCGSAPELETALTAHLPQGQTVMSLNVPVELTDT-
DDRY---------REMVNGLLQILQQTLKSNGSDTIFLLVVFS-TDEVDHAHLLTGLSGLLKTAEQEYSRLTTQML-----EIAAVDDAAQLYAMLSANL
HQPGSDRIRYQNRQRQVHTWKPLSEEIEL--SAKPWRHKGVYLITGGAGGLGRMFACEILTQSPGRVILTGRSA------IDPAQVNALRKY----GGQV
EYVQLDVTDRAAVQALMLH--LRQSYGLHGILHCAGVLQDGRLLAKTTAEVEQVLAPKVTGLLNLDEASRTMELDFLVLFSSLASALGSVGQADYAAANG
FMDAFVDHRNALRNLGQLAFDWPLWREGGMSVEAETEQLLQQRGMTAMRTETGMNAFYLGLASKSTRIL----------------VVEGELARIQQTVLR
REGVLGIQRLPKPRIEKQPQATSAPE-----------------TGQSDGTHGVIR----------RLKVIVSQLVHI-----DPIDLDVDEELNAFGFDS
ISLTRLAGELNKEYGLSLSPVVFFEFPTLAQLAEHLLAE-----------
>tr|E1ZE56|E1ZE56_CHLVA Putative uncharacterized protein OS=Chlorella variabilis GN=CHLNCDRAFT_57723 PE=4 SV=1
--------------------------------------------------LPTGSGANGGRALALLAGTAVNQDGRSSSLTAPNGPSQQEVVYQALGAA-
--RL---------EPFAVTALQMHGTGTSLGDPIEVGALAAA--LVERRPASWAAPLSLLAAKSWSGHAEPGAGMV-----GLVHAQQHVNPYVAGAMEM
AAGKQAGWAVPRQPGALPTATTAGGNRGQ--LAAIKAARGRIAVTGGMGSLGLVLARWVEDAELAQLVLFGRTGR----LAGTEAAALLANS----AAAM
TLAMADVAGSEGSSSALEP--AAGSMALTALFHSGGLLADATLAKQAPAGIRAVFSAKVTAAQRWQHTVQAQPAAAQVLFSSVAALLGSGGQTNYSAANA
ALDAMASNHQQKGLLTA-SVQWGAWSGGGMAAQDRSTVLRVQRGMAMIDAARGMGALFTAVPFNWPTFIGRL----------GGKPVPSMFAAFADQ-VA
PALTAGRRPAARPVVAAPRVARQSAV-----------------PPHTSAALEVFKQ--------HVAAEVAAAARSI-----LGADVGANEPLVAAGLDS
LSSVELRNSLEGKLGLELPSTLVFDYPTVNAISQFISTN-----------
>tr|G8YZM2|G8YZM2_STIAU Mixed trans-AT type I polyketide synthase/nonribosomal peptide synthetase OS=Stigmatella aurantiaca GN=rizB PE=4 SV=1
--------------------------------------------------EQGTAFRRVEARRYTIRAREQSDYQTLLEALAADGIDHHTFVHAWRGDGG
EEEL---------AAGLHASLFLVQAAAARTQVLNLRLLYLHE-SEGGQRSPWTGALAGFGKTLTVEHAGASVTVV-----AATAADLRGRPFIDLVRRE
LQAEEGEVLYVEGQRQVRTLRETPPVSAT--VHP--RAGAVYLLTGGAGGLGKIFANRLAARGGR--LVLCGRS------PHSKKIDSVVEQ----GGEA
IYVQADLSREEDVARLIAK--AKHRFRIDGVIHAAGTIRDARLLRKSAEQVAEVVGPKVAGVMLLDQALRSESLDAFVVFSSVAALVGNVGQCDYAFANA
FLDGFVETRETLRERGERSLNWPLWREGGMAVDAQTEAWFENVGLLPMSTAVGLEALDAALSLSTPQLF----------------VAEGNVERIRER-FS
PTRSTALRDKPSPVRPDTLRPRLTAI-----------------AAE---------------------------ILKQ-----EPRKISPERELGEFGFDS
LSFTELANRLNSEFGLSLTPALFFEHSTIEQLTAHLAPR-----------
>tr|Q6MZA4|Q6MZA4_MYCUA Type I modular polyketide synthase OS=Mycobacterium ulcerans (strain Agy99) GN=mlsA1 PE=4 SV=1
--------------------------------------------------EPTQQLPRYLHDLHTSTDLHTSTTEADVVVWPVPVPSNEELQAHQASDTA
SSRI---------HTLTRQTLTVVQDWLTHPDTTGTRLVIVTRHTSAHDPVPDLAHAAVWGLIRSAQNEHPGRFTL-----LDTDDNTNSDTLTTAL--T
LPTRENQLAIRRDTIHIPRLTRHSSDGAL--TAPVVDPEGTVLITGGTGTLGALFAEHLVSAHGVHLLLTSRRG------PQAHGATRLTDL----GAHV
TITACDISDPEALAALVNS--VPTQHRLTAVVHTAAVLADTPVTELTGDQLDQVLAPKIDAAWQLHQLTYEHNLSAFIMFSSMAGMIGSPGQGNYAAANT
ALDALADYRHRLGLPAT-SLAWGYWQTHTGLTAHLTDVDLARMGLMPIATSHGLALFDAALATGQPVSI----------------PAPINTHTLARH-AR
DNTLAPIPRRRAASAATDLAARLNGL-----------------SPQQQQQTLATL----------VAAATATVLGHH-----TPESISPATAFKDLGIDS
LTALELRNTLTHNTGLNLSSTLIFDHPTPHAVAEHLLEQ-----------
>tr|A0A0M4KE03|A0A0M4KE03_SORCE TAT polyketide synthase OS=Sorangium cellulosum GN=ctoE PE=4 SV=1
--------------------PGDVLLFDAGDGIFERLRARWTGGGRVALVKPGDGYREIAPDIHAIHPARPEDHARLLEELARRGAAPRIVLHVAPRGAL
APSEAVADVH--LERGVLALFLSVRSLLERRERGALHVLHVSAVEGGEPQP---QHAGVAGFARSLRKEDPRVRCRAVALDGAPD--PAAYVDAMLLELS
TDDGAAEVRHAGGERFTRRVAPLDLPDRARV-----REGGGYLITGGAGGLGARLAAALASASRVRLVLAGRSGMDAR---KQELVRSLS----AGGSDV
HYASADLSRREDVERLVRE-ARRRCGAIHGVVHAAGVLADALLVNKTPEAVRSVLLPKVRGSVWLDELTKGDELDFFVLFSSIAAVVGSAGQCDYGYANA
FLDELARWREGARSGRTVSIDWPLWREGGMTVDAAHRASLEEAGLALLDTGAGIEAFHAALRLPSPQ--------------------------V-VVLYG
-DPA-----R-----AAALLTAG-GGAPA-ESPSSPL---EGG-AD-------------------LREAAEAYLRSLLSSHAKVPRLRPSEPFESFGIDS
LMSMTLVRALE-KTFGELPKTLFFECRTLSELAVYIDNH-----------
>tr|G2G4P9|G2G4P9_9ACTN Pks12 OS=Streptomyces zinciresistens K42 GN=SZN_02262 PE=4 SV=1
------------------------------------LGRLKAGESVLVHAGVGMAAVQLRHLGAEVYATASP---GKWETLRAMGFDEKHIAS-----SR
-DLDFEPRFMAATGRGMDLV---LDSLAR-----EFVDASLRLLPRGGRFLIDVRDPEV---V---ARDHPGVRYAAYDLDAADYDMLVELVELFDSGAL
HPL--PVTAWPDAVRYISQARHIG--KNVFTMPRALDPDGSVLVTGGTGGLGREVARHLVERGVRNLVLVSRRGPDAEGA------ADLKAELTRAGASV
TLAACDVADRAALERVLSGIPT--DHPLTAVVHAAGVLDDGVIDTLSPKRIDAVFEPKVDAAWHLHELTRDTDLAEFVMFSSAAGVFGSPGQGNYAAANS
FLDALAAHRR-GLGLPAVSLAWGPWEQAGMTGTLADMVRMAREGMAPLSMAGGLRLLDAGAASEDAL-LVPLETSALGGQT-------------------
---------G----VPTLLRGVVR-VRSRAA---------ADGKAAPE---SAKVRL-----AGLAGAELDRALLDLVRGHSGAQSIEPDRSFQSLGFDS
LAGVEFRNRLNSATGLRLPSTLIFDNPTPAALAEYLRGR-----------
>tr|G2PEV9|G2PEV9_STRVO Beta-ketoacyl synthase OS=Streptomyces violaceusniger Tu 4113 GN=Strvi_4164 PE=4 SV=1
------------------------------------LGKLQEGETILVHAGVGMAAVQLRHLGAEVYATASP---GKWDTLRAMGFDEKHIAS-----TR
-DLEFERRFTEATDRGMDMV---LDSLAR-----EFVDASLRLLPRGGRFLIDVRDPEV---V---AQDHPGVKYSAYDLDVADYDMLVDLVDLFDRGAL
HPL--PVTAWPDAVRYISQARHIG--KNVFTMPSALNPEGSVLITGGTGGLGSEVARHLVERGVRNLVLVSRRGPDAEGA------ADLKAELTEAGASV
TLAACDVADRASLDRMLSDVPA--DHPLTAVVHAAGVLDDGVIDTLSPKRIDAVFEPKVDAAWNLHELTRHLDLAEFVMFSSVAGVFGSPGQGNYAAANS
FLDALAAHRR-ALGLPAVSLAWGPWEQAGMTGTLADMVRMAREGMAALSMADGLRLLDAGRTSEDAL-LVPLETSALSGQT-------------------
---------D----IPTLLRGAVR-VRSRAA---------ADGKATAE---SAKEQL-----AALSGAELDHALLALVCGHSGAQSIKPDRSFQSLGFDS
LAGVEFRNRLNSATGLRLPSTLIFDNPTPAALAEYLRGR-----------
>tr|K3VA96|K3VA96_FUSPC PKS6 OS=Fusarium pseudograminearum (strain CS3096) GN=PKS6 PE=4 SV=1
------------------------------------VAKLKAGESILIHAAVGQAAVILQHLGAVVYATCGS---QEKER-ESMGVNPSHIFT-----SR
-SPAFGPALRAATNKGVNVI---LNSLAG-----ELFRESLECLTSFGRFIKDFLDDAL---M---PTKFLLITFACVQMINEDKPLLNDVVELVASGQL
KDEV-NLQLYESAFRLISAGKHMGK-VINI---PKLLPDATYLLVGGFGGLGVRLIRWLASRGAKTIVTMSRSG---PAA------KTCIEEMDSLGVRI
IAKSCDISSKEALQVVVKELEDVDGAPVRGVINAAMALEDAMFDQMTHQQWVSSLAPKVAGTRNLDEV--LNYMDFFVVLSSIAGIIGHQAQANYAAACT
FQDAFMHYRR-SQGRASFAIDVGVVSDAGVSEAPAVFSNMKRQGFSFISVAELLATLDYAL-SNGPDCSIGAEASPNNAELEQ-----------------
--------RR----ISHLVKDSAN-G----A---------AGGS--DA---DHIGH--------IRSAKTAEEALDAVGQVTPVDRILPHRTLDSYGVDS
LVAVELRNWVVAIVAADLSLLLIRESRSIEELIHLVAGK-----------
>tr|A0A0B4HLK4|A0A0B4HLK4_9HYPO Beta-ketoacyl synthase (Fragment) OS=Metarhizium majus ARSEF 297 GN=MAJ_07758 PE=4 SV=1
------------------------------------TARLSAGQSVLIHAAIGQAAIMLKCLGVTIYATAGS---QEKGLQREYGIPAERIFT-----SR
-DASFATAVLAATKRGVDVV---LNSLPG-----PLLQASLDAIAPLGYLIKDIESNSL---V---ALESFSISLVSLTLLR-RGPALGEMVRLIEQQAL
KPVH-PIAVYQAAFRLVQTGAQMGK-VVGVTARVRLQADASYLIVGGVGGIGRSVAHWLVSHGARNLMLLSRTANKNTHG------ARFVRELREAGCRV
KPVSCDIALASSLTTALRAC-EDDGPPVRGVIQGAMLLRDAVLEQMTLDDWRGGLRPKMHGTWNLHTEFSQASLDFFVMLSSVSGVVGIASQANYAAGGS
YEDAMARWRQ-SRGLPGVAIDLGPISDIGVSATARVAERLRKDGFAMLDEDTVLRALHAAVLHPGGRAIVGS---APGPQDAT-----------------
--------GR----S-QLGRDARF----------------AAA---GT---SLAAQ--------LAEATDQQEGARLVGAMTPVAEIDLAKPPAHFGVDS
LIAVELRNMLVLQAAADISIFNILQTASLAALAALVAEK-----------
>tr|A0A0H4TMU3|A0A0H4TMU3_9CYAN ColF OS=Moorea bouillonii PNG5-198 GN=colF PE=4 SV=1
---FQIEWQVQPPLSQDSLQPGQWWLLAENKGLASELAEYFTQQGQCHWLESDPS--QLS----------KERLETVLSQLTNQTLPLHGIIYLWNLNKP
SDELPDGDWQQSIK-PLLQLVQVISQLPGFQS-----KLWVVTRQAQAVDPVAISQTPLWGLGRVIAQEQPQLWGGLIDLEENQ---ELTAAQQVYTEVA
TQPGGLQVAYRQGKRYWPQL--VRYPKIP--PSLKLNSQSSYVLSGGLGALGLQIAQRWVEQGARNLVLLGRRGITN--EIQQQKIAELEA----AGAKI
QVASIDVSNWTQLRQAWTEWQST-MPPVRGVLHAAGVLDDGLLENQSWERLVKVMSPKVEGGWNLHRLTQDENLDFFICFSSAASVLGSAAQSSYAAANA
FLDGLCAYRR-SLGWPGLSFNWGPWSEVGMAAQMAQKQRWAMMGVKLIQPEQGLQVLEQQLGAGGQLGVLAFDWEVLSQKLSPTQ----------LNFFA
--------QVLPPEVKDLVQSTT--ER---SSQLQQQLL--------------------LVSEAQ----RKQLLRQTLQEVACVLGLPPTDGFFELGMDS
LMAVELRNRLGQLLAVNLPSTLTFDFPNIERLSDYIISE-----------
>tr|A0A0G3A003|A0A0G3A003_9DELT Malonyl CoA-acyl carrier protein transacylase OS=Archangium gephyra GN=AA314_06711 PE=4 SV=1
---YALEWQSAPRASAPAPASGTWLLLCDRGGVGEQLASSIEAQGACVKVDAGDA--TAL----------ERVWR-----ERSASSPCAGVVYLGALDVT
SVEGPI---RESCV-SVASMLRVVEGSPEPGG-----RLWVVTRSTQSVGKVEPAQATLWGLGRSVALESPGRWGGLIDLGPED---G---ARQLWEELR
SARDEDQMVLRGGQRYVARL--VERESES--KPVPVQAEATYLIAGGQGALGLEVARWLVRRGARHLVLTARRAMPE--RSQITGVRELEE----AGAKV
LLAQADVALREDMAALLERMRAS-MPPLRGIVHAAVVSSTSRVRDLDADTLERVLAPKVAGAWNLHTLTRDEPLDFFILFSSISAVWGSSGVGHYSAANS
FLDGLAAHRH-ALGLAATSINWGLWSGRGAASE--EQGRWLMMGVEVLDRQAALGWMERLVGSRVPAMVATIRWERFLPIFEARG----------PRPLL
--------SRLRTEL-ELPVV-----K---SSAPAPWRE--------------------APTATA----RREALRKLVQSVSRILGLQPGQGFNEMGLDS
IMAVEVKERLQKALSVPLPATLAFNFPTVKALTEHLSSL-----------
>tr|S9Q289|S9Q289_9DELT Malonyl CoA-acyl carrier protein transacylase OS=Cystobacter fuscus DSM 2262 GN=D187_009025 PE=4 SV=1
---YEVEWRPSARVSEVSPARGSWLVLG-EGEEGRRLAAHLQSQGACVTVAP-----SAF----------AGVWR-----EH--AASCTGVVFLRALET-
----EA---HEACL-ELASVLHVLEGTPDAAA-----RVWVVTRNAQSASRVNPSQALLWGLGRTASLESPQHWGGLIDLGPEE---G---VERLWEELG
AADGEDQVLLRDGQRYVARL--LEREAEL--QPLPVSADATYLITGGKGALGLNVARRLVRRGARHLVLTMRGAFPE--RSRIAMVRELEA----AGAEV
WLAQADVSQRDAMAALLERMKGA-LPPLRGIVHAAGVSATARVADLDAETLGRVLAPKVDGAWNLHALTRELPLDFFVLFSSVAGVWGSSNGGAYAAANA
FLDGLAAHRR-ALGLVATSIDWGLWEGAGLATI--EERVWLEVGLDALDREAALDWMERLVAARVPAVVASIRWERFRSLLEARR----------ARPFL
--------ADLRVHGRALPEG-----K---APPRPAWKD--------------------AATPSA----RREAVGALVRTVSRTLGLSAGQGFHELGLDS
IMAVELKGRLQEQLGLTLPATLAFNYPSVRALTEHLDSL-----------
>tr|A0A085WVX2|A0A085WVX2_9DELT Malonyl CoA-acyl carrier protein transacylase OS=Hyalangium minutum GN=DB31_0096 PE=4 SV=1
--LLVKRWRPAPAPVTAPTLRGMYLVLLNGEGAIDVLKDLGSQPEQWIAIKGASGLPRLTAREYELDFSDGEQGTRLITELLSRHPQVNGLVDLSDVYAA
PR--VSPD-RDAGKV--AVLQGLLRHTGQ--APLRILHFT-HGLVPFENTVPTLAGATVAGIVRMLGAEYGRVRAVTVDVDLSC-DRSEELLALVAAEAS
ADTGMGEVCYRKGTRYLPYLEEVAVSAPGEALGFPVDPARTYVITGGTGGLGFEAARTLVAKGARRLALLGARTLPPRDSTEQDVATRVRRVLEQAGAQV
ALYHGPLSDEPRLAAFFSDTRKRL-GAIAGVIHCAGIVSQRPFSQKGLEDMRRVWEPKVRGLIVLSGVLKADTPDFFLLYSSVSAVVPSLAVGDYASANG
FLDAFAAYQAGKSRTRFLALNWPSWKDTGMGEISS-------------PRYTG--LGFTAHGTREG-----MELLEAALSLPD-----------------
---------------TTSVMPCVVNRATLRLDRMLSTQGAEPAAPARAP--QAAP-AAQADTPTPLFAATRELILELLSREIDKARFQGDAPFGDYGVDS
IVIADLVTKMERFTGKPVDPSIILEHSTLDTLSHYLSE------------
>tr|A0A0C5VNB2|A0A0C5VNB2_9GAMM Polyketide synthase modules-related protein OS=Gynuella sunshinyii YC6258 GN=YC6258_03740 PE=4 SV=1
--FFAPVWQPQTLTAS---SRKTVLLLVPETEVLAWSTRMDDRVADWYVIRFAGLMPRLSKRELEIDVWAEQAFDDLLAMCAERHLQPDWIVDVCDFGPD
-------SDQWQARI--RFLQLCVRAWS----GLALFQIS--------DRQSSRTRQWFTALYAGLAAEYRQISCRSVVFD-QA-PPFTELEPLLERELQ
-GGDSRPVSICDGQRQILSYQLCNLPQAGQI--RGLDSEAAYLVTGGLGGLGLQAATLLRQLGAKHLILLGRRQPDETRS-----------LLSNGSAQI
EYFHDLSTLA-------ERLQQQP-VRIAGVIHCAGIDTQGEFVNKPVSAFTDCLAPKVVLAEQLTPHLDPAALTFFIAFSSVSTVVPALTAGDYGPANA
ALDQWVATMAGQPQSGFVSVQWPSHQQGGMPVVVS-------------DVYRD--TGLANLTREQS-----DDILKILITLAL-----------------
---------------QSTLLPHVGDGSPV----LFSKDVFEPA----------IK-VPGE-IPRPARTLILTRLTALFARQVDESALQAGVPFDELGIDS
ILIADLVRAIESEFDCILPPSAILEYPSLGQLTEYLGE------------
>tr|C5BJI1|C5BJI1_TERTT Modular polyketide synthase, type I PKS OS=Teredinibacter turnerae (strain ATCC 39867 / T7901) GN=TERTU_2202 PE=4 SV=1
--FYRPAWEPCPLESNAASYTRTILLLVRDDESVLWHERIAQSPRNWHIVRFSGLYPRLSKTELEIDLNAENPITQFIQLLEHRHIRPDWVIDAFDFAAT
QE--ATASSFWLQRV--QLLQSCMRAWQN--AGVHFWHLS--------GSNGSAQSAWFETLYAGLGVEYKNIQTHQLQLE-SC-PVIREFEAVLEQEAM
QPATQQSVSRRSGSRNVRQFEPITLSTNSSS--VFLRADAVYVVTGGTGGLGVVAAKLLISCGARQLILLGRKPLGEKGE-----------VLSEKGATV
NYSSSVNDLK-------TRLQSER-LFVAGVIHCAGVDTQGDFINKSSSSFEKCLLPKTELAQRLKPHLDPAKLQFFIAYSSVSSVVPVLTAGDYGPANG
ALNSWVAAQAEHSNSGFVSILWPSHESGGMPVITS-------------ERYQN--TGLACLTEDQA-----DQFLRVIMQAAI-----------------
---------------QVLILPHLDISLPL----NLFPQKSSSAMLAGVS--EASN-LRGENIVSPGSSDLLASLTTLFAEKIAQENLAAEAGFSDLGIDS
ILIADLVRAIETKFECVMPPSAILEHPTLAQLADFLNE------------
>tr|A0A078KNJ1|A0A078KNJ1_9FIRM Uncharacterized protein OS=[Clostridium] cellulosi GN=CCDG5_0919 PE=4 SV=1
------------------------LVITDGTGIFDEFISVLKAKATLIKAQLGSQFSRVD-ENYIID-GTQKDYERLVKDVEEYGISTV--VYLLSFTGN
KTINSAEELEEVQNSHSEGLLYLVKALGNTENKIELVIVSDNVNEVTGRESINPENAITFGMGKCIGMEYENIRCRMIDFDE------HTDAAVLVKELC
NEADDWVVAYRDGERYVDVIEKVDKSALND-SGIPQVSEGVCLITGGTGRLGLKAAKLIASKGKANIALVSRTPVPDRTAEADKVINTVREI-EKSGSKV
RCWSCDITSAYSLSNLLAELRREY-GRIGGVIHCAAVGGGALINQETWESVNAVLLPKVRGTWLLDKLTRQDKPDYFVMYSSGITLIGGYCSCSYTAANS
YLDSFAAARN-RSGLRTLAIDWPVWENDQLDKNLMFK-------ILPIEK--GLQCL-DELMH--------KDIARVIVGEMNFE-------SEILTMEG
-----RIPLRLSDELKTKLRTKTTETKPVLS--------------------------SKTPSYDAAGSDTEKMIAQIFADVLGYERVGKYDNFFELGGNS
LLAIKA-EAIASKRNLNFSYSDIYKYQTVEQLAAFIDDS-----------
>tr|X0MVA5|X0MVA5_STRA9 Uncharacterized protein OS=Streptomyces albulus PD-1 GN=P354_17195 PE=4 SV=1
----------------------------------------AGRADRIVLARPGTAYQRQDAHTFTLDPGRGADVDRLFADCAADDLLPGVVLHAWNDPDG
ADGLAAGAVDAALARGLLTHFHLGKALLARKRPVRVL--HLHTAGVDGPSP---LQDAVAGFARSVRLENPRLVHQVVGLDRR----EHALATA-VAELG
DATDPAVWVHEDGRRLVHGHRRIDLPRPADR-PTPVREDGVYLITGGAGGLGLLVAEHLAAQARTHLVLVGRSEPDQDA---RRRMAAIE----AHGGTV
RHLRADVADAESVRELVARVRAEHG-ALHGVVHAAGTLRDSFLLKKTAEEFAAVLAPKIAGAVHLDHYTRDEQLDFFVLFSSIAAAFGNLGQTDYAAANA
FLDAFAEHRTVARHGRSLSIAWPHWRDGGMALAAHDAAVLRERGVASLGNEEGLAAFDDALA--------------LPGG-------------AVLVAAG
--DAEVIAGRLA-AAGTAADDRPGGDAGA---GAEAAPTASGGADDGAE-------LRGAVAF-----LRELVARKIGAE---ASGIDPKALLARYGIDS
LVITELNRALEDRFG-ELSKTLFFEHDSLEEIADHLAE------------
>tr|F1T733|F1T733_9FIRM 6-deoxyerythronolide-B synthase OS=[Clostridium] papyrosolvens DSM 2782 GN=Cpap_3713 PE=4 SV=1
----------------TKEDRT-LLFIAEDMKFCNNYGYFS-ENTISVYIGNEAS-SNM-KYNYQINKTDSASYINLYEQLNKKKCSEWDIIYFS--QSR
NT--GADTSAKEIDNSIQTAYSLIRAFSKDYSTIR--FIHGFTKDNH---T-NYVNIALSGMLKTISVECSNIQFENMNE--------REICSRLIEEVN
FISDGTDISYISNKRYISEFKPIQKSET-ENKQLDIFNQGVFIVTGGMGALGQILAEQILVYRPQRVYLLGRKYPDK---AILDSVSRID----PSSTVI
KYLQCDIEDSIACQQVIENILEKDG-HVTGLFHCAGVIRDAIIVNLKLEDFYQSVNPKIKGLINILDSKYGLDMKFVKLYSSITSVMGNMGQTAYSYANG
YLNAFAYDQSKYHMFNIQAICWPYWEQGGLTVGEKLNRLYEQTGQKPLSTANGKIVLENLMSLDSKCP-IAMYGDKAKISRYMKEVR-------------
---------RQYT----MEENEIQGDEIV---SASKLKEDVT-----D------------------------YVQGIISDIIKKSKLNITTTWENYGIDS
LAIMRFNEIIED-VIPNCPKTLMYEYRNIEALSECF--------------
>tr|S6FRI4|S6FRI4_9BACI MlnC OS=Bacillus methylotrophicus UCMB5033 GN=mlnC PE=4 SV=1
----------------NQQAPGNMLIFDQDNRLFQHAEMMNGDHNRVILVTPDSD-YRIERNRCTINPSDENHVEMLLSDLAENGFTPDVVLYLWNGEIR
EF--TEKSVNETLCRGINSLFLLSKALMRRNEPVM--LLHIYWTSGL---N-QPFHEAVGGFMKTVNMESSTIQIRHEDSDKNPPV--SEMWDAAISEIQ
RQTDECEILIDSYTRYVKGLQHIDNPEH-ANGSVTYQKGGIYIITGGAGKLGLLFAEHIAKENQAVIILTGRSFLTA---DQKERISKLN----ESGSIV
EYQRTDITDRTEAERFIFGVKQRYG-SINGIIHAAGILRDSFLVNKSLSDFTDVLKPKVYGTIWLDELTKDEDLDFFVLFSSF-SAYGNAGQSDYAYANH
FMDSFAVLSQLSRNGKTLSINWPLLKDGGMSLSNGINQIKEKYGMTPMRTSSVLEAFLKMLRSSFTSL-MPAEGKRDKMIKALSIQR-------------
---------NTAA----ADQDTLTAEHDE---EEEYAKEKVN-----D------------------------YLIKIISGVLKAHKINAKDSFEKFGINS
LMIMSLISKLED-TFGDLPKTIFFEYQNIEELSNFF--------------
>tr|A0A0K6L968|A0A0K6L968_BACIU Polyketide synthase PksL OS=Bacillus subtilis GN=pksL_2 PE=4 SV=1
---FKRDWISSKNDDVQKQAPRSILIFDRDKRLSEYISMLYKDQVHVILVTPNVYFSCPEQNVYTIDPSNEAHYENLFADLEKSKFTPGCVLYLWNSAVP
E--LSEELIHKALLNGILPLFVLTKALINYDNTK------LLHMYWTNGQIQPFNE-AVGGFIKTVNMESSKLKAKTLQIHREEPNS--DPAASQLWEME
ILIDSHS-RYIKGMQHVDLEKPLALK------HVSYHKGGVYIITGGAGKLGLIFAEHIANEVEAVIILTGRSA---LSEVQREQLRKLNA----KGSFV
EYIQTDISERIKAEQFIRDVKQQHGQ-ISGVIHAAGLIQDSFIAKKNLSEFVEVLKPKVFGTIWMDELTKDENDFFILFSSVAA--NGNAGQSDYAYANS
FMDSYAMFRQLNRNGKTLSINWPLWKEGGMNLDDSAVVHLKEFGMIPIHSTAAFKAFDK-MMQSSFSNIMPVDRDKLLKTIPFRK---------------
------------------------------LTPSDNKKNTEDEIVIKDKVN-------------------DYLIKTICSELKPNHKINAYDSFEKFGINS
LIIMSLISKLEDTFG-DLPKTIFFEYRNVDELADFF--------------
>tr|A0A0F7EJ98|A0A0F7EJ98_BRELA Uncharacterized protein OS=Brevibacillus laterosporus GN=EX87_20440 PE=4 SV=1
---------------------------------------------RLVTIKVGECFQQKSETEYELNPANKQDFQRLFEKLKKLEFKPGGILHTWGITIE
S---DV-LEATTVQRTLYSLVYIAQSLG----EQNMTNLTNNMNEVVGGDLLYPEKSTVLGTVKVIPLEYQHITCTSIDISLPERGSKEHLVKEILFN--
--DTENIVSYRGSHRWLPSVKQIRLQKRHT--SSRLREKGVYLITGGLGGMGLHMAEYLAKTVQAKLILVSRSDFPKATWKDYEKIEKLRE-MEEYGAEI
TVISADISDKEQMSKVIKQTES-MYGSINGVLHTAGVAEYDGVQTKQKKNIEKVFASKIYGTLVLHHLLQGKADFFGICSSLAPVIYTKLGQVAYCSANE
FIDSYVHYYNSFNDGVVFAINWADWQEVGMSVES-------AKHWGQKLKLE----NSDSILEDGILPHEGVEAFHTVLENDYPQSPEDLIEKIS----S
YKQI------GISTLQAILEE--SNDYKSHYER-----------P---------KLST---DYVEPRTEMEKMLCKIWSKIFGVEEIGINDDFLELGGDS
LKALTAISQIHQVMGIRVSLPEFFKHPNIKEFSNFILER-----------
>tr|A0A0J6BPS4|A0A0J6BPS4_BREBE Uncharacterized protein OS=Brevibacillus brevis GN=AB432_12610 PE=4 SV=1
---------------------------------------------RLYAEALRTCFELIGQDEYVEMPGALEGFSRPFAL------DQAPLLRIRLVCVE
KQ-RHVMIISDGLSSERFLAYYDGQTLG----DPKIQYRRPSIKNFAGSFVLADEKAALFGCFSILLAKYSGQNEILILRSYPEGGKRVELVQQIEKER-
--DLSRNPLFDTMFTWEQRD------------RSQLIIHGRYDFHSGIARMGRHFQQIVDEILQSPIRLILREGFNQVVWEGYRFIIGLLA-IEKAGCAY
LPIDPTT-PAERIQYMVEDSVL-SHAGLVGIANTAGVVVYDLVLTHGGMTNRLRWMADQYGMDDKEVVLIGGDDYNLICEQEVPSMLASFSRRCICSGEE
LSIEDVSYYEVQEEDQLIPIGEGGFAPIGVPGQV-------AKGYLNRPELTAETGDLARWLEDGNIAYLGRKGFRIELGE-IESAYTDQIETVAVLFSA
KDKI------DTGKLKTHLQRH-LPAYPVHYQRKA--------LPH-------ITVSD---NIEKPRRKEGQLLVSIFKETLNIENLSSTDHFFELGGNS
LAAIVLKSKISAAFQVQLTMQEVFEHPTIRELVPLILQK-----------
>tr|K0UK51|K0UK51_MYCFO Non-ribosomal peptide synthetase PstA (Fragment) OS=Mycobacterium fortuitum subsp. fortuitum DSM 46621 GN=MFORT_25954 PE=4 SV=1
---------------------------------------------RLWFESLRTVFDAPGGIGWDVVDATEHAVNEAVDVRYAFDLSSEIPLRANLFRVS
DH-EHVLIAADGWSLSPLSVAYASRSRG----QAAVQYPYPPVADQLGSVDWPAELQQMQAALAVLLSKLGATSDVAVLRVDLDGDPTVVLVERINPAR-
--SLTRHPVVQVALAWQNLPWQD----TGP--ADGLSLGDPLPVETQTAALVARWQRVLAAMTADPLDLLMDAWGHRITADGYRKVVAMLA-VLKAGAAY
LPIDPVL-PDARIEFMLEDAAI-VTTGLADRLAGCELLIVDVVITHRNVTELLGTPD---TFMAGQTWTHGGSEQALLAAEQVPSASPERLTTLLVAGEP
CPADCASRTALAAGSGAPPIGSLRQVPAGVVGGV-------GLGYVGRTGLTGSTGDLVSWGADGQLHYVGRAGYRIELGE-IQSGLDGVDQAAVIAVTG
TAEPG----K----LRAQLAEQ-LPAYPAAVVTRA--------LPA-------PEYQDI-DNYRAPSTPTEEILTEIYARVLGVERVGVDDSFFDLGGDS
LSAMRLVAAVNTALDTGLAVRVLFEAPTVAQLAPRVG-------------
>tr|X8DM27|X8DM27_MYCCH D-alanine--poly(Phosphoribitol) ligase, subunit 1 OS=Mycobacterium chelonae 1518 GN=dltA PE=4 SV=1
---------------------------------------------RLWFESLRTRFDAPGGNGWEIIDATTGQLDEAIAVCRSFDLAIEIPLYARVFRIA
EE-EHVLIAADGWSLTPLSVAYASRCRG----HAPVQYPYPPVADQRGSVQWPPELQQMQASLAVLLASISGTSDVAVLRVDLSGDPTVVLVERLNPIR-
--SLAHHPLVQVALAWQNLPWQD----TGP--ADGLRLGDPLSVDTQTAALIARWQRVVASMTADPIDVLVDRWGNRISFNGYRRVVAMLA-VLKTGAAY
LPIDPAL-PDVRVEFMIGDAAI-TTADLTDRLAGYALTVIDVVIAHHNVTALMGSPA---TFLAGHTWAHGGSETALLVAEQVPSATPESLDSLLVAGEP
CPGECASRTALVGGTGSPSIGLLRPVPPGVVGGV-------GVGYAGRTGLTASTGDLVRWRADGQLEYLGRAGYRIELAE-IHSALDGVDQAAVIAVTG
TANPA----K----LRAQLAEQ-LPAYPVAVVTRA--------LPR-------PEYQDI-DRYRAPGTLTEEILAGIYARVLGVERVGVDDSFFDLGGDS
LSAMRLIAAVNADLNAVVSVRTVFEAPTVGQLAPRIA-------------
>tr|B0JJW9|B0JJW9_MICAN McnC protein OS=Microcystis aeruginosa (strain NIES-843) GN=mcnC PE=4 SV=1
---------------------------------------------RLWFEALRTNFITVDGITV--VDLQAIASQELAQAIQPFDLAGEPLIRITLVVLS
ET-EHLLIVSDGWSMGVLTALYNAYIQG----LSSIQYPRPNQQSFAGGFSLSWELTELLTAYAVLLYRYTEQEDILILRIDLSGKPNFMLVEVLQPER-
--DLSHAPLFQVDFLLQNSPPS------------PLELTGPLTTENDTARLTGNFITLLEALVVNPLPLLLLKDWNAVVFEGYQYIVGLLA-VLKAGGAY
IPLDPDY-PQQRLTYMAEDALL-TQESLLDSLPAEDV-GVIVVLTHEALVNHSWGISEVFGLTESDRVLKGGTTADFIEQESLPAYATVPSSVVAVGGDA
VLPETAIVHD--EKINSVLIGNLQPVPIGVKGRL-------ARGYLNRPELTAETGDLARYLPDGNIECFGRIGFRIELGE-IEAQNIDVQTSCVIIIVA
HYERI----PMISELRQFLSSK-LPLYPQAFVRRA--------LPA-------PDKIGNRDQYVAPRNGIEEMLVQIWTEILKIDQVGIYDNFFEIGGHS
LLATQLVSRIRSLFKIELPLRSLFGAATVAELAHLIGQL-----------
>tr|A0A0P7CW66|A0A0P7CW66_PSEPU Non-ribosomal peptide synthetase OS=Pseudomonas putida GN=HB4184_17205 PE=4 SV=1
---------------------------------------------RQWMESLRTIFEEHDGIEY--HDLS-RALQQRLHALTPFDLEQGPLIRVKLFQGG
PQ-EQVLIVSDGWSMSVLAAVYNAHTTG----QSAVQYIRPQVQSYRGGVRLPAALTAFLASFALLLSRYSGRETLNIARVAVDPLQSFVLVEALKPER-
--GLGHNPLFQVMYNHLSDLGER---------VFGDSVQGEVDLVEHTTRLASVWVNLLGALASNALPLLALEAVDPLVLDDYQKVVGLLG-ILKAGGAY
VPLDPQY-PQERLRFMVQDSLL-TQPHLTPMLPVSTAVTCLEVVAHRALSVFCSVAADYSRLDASDRVLCGA-EKQAIVTHGITAYAGACASQVHVGGEA
MPMEVTTVQDGAGGKAIVPIGGLVLAPAGWVNCL-------ARGYFNRPALTAETGDLASARVEGVLDYVGRIGLRIELGE-IEAEHARVREAQVIDLVI
EGGVEPQ-DALRENLASHLKAA-LPDYPAHLMRKA--------LPR-------PDLSLEQPAYVPARSEREKQIAAIWAQVLKVERIGLTDHFFELGGHS
LLATQVTSRIRQALGLEIPLRTLFEAPVLADFVA----L-----------
>tr|E1TCG1|E1TCG1_BURSG Amino acid adenylation domain protein OS=Burkholderia sp. (strain CCGE1003) GN=BC1003_2219 PE=4 SV=1
---------------------------------------------SLWFPALRMRFGEVEGVRVLELPCTSEALADCLVVRKPFDLMSEPPVRATLVRVA
DD-QHVLIVSDDWSIGLFSRLYRERCAA----GASVDYVRGGARRAAGATRVPAATTKLLAAFDALLYRYSGQSDIRLIRTAPRGAMRASVVKAVQPER-
--ELTHTPLFQVLVNQQQRHDLT----T-------SFGDEVQEVDSGEARIARHFTRLLEQWSSAPFELP-------LVDGNYAEVASLLG-VLRAGAAY
VPLDPSY-PAERLAHIVDDSVV-TDAESLAQHAALDAAALRDVVTHENVARLFDATQSRFAFNEKDVWTHGAEAHALLCEQQVPSATNTLDSAVIFGGER
LEPAHVTHRTAALREARSVIGDLNRVPVGAVGGL-------ARGYLGRAALTAQSGDLARRLADGDLEYLGRNGFRIELGE-IQAAHPEVRDAAVLVVVP
RGAPHT--DD-VARWQAWLAAR-LPAHPSSYVRRA--------LPA-------PEAVAHAAQAVAATTPAESALLVVWRAVLRRDDIGVTDNFFVIGGDS
ILSMQIVSKARD-AGLHVTPRMVFESPTVQQLARVARAL-----------
>tr|A0A0A0WVD4|A0A0A0WVD4_9BACI D-alanine--poly(Phosphoribitol) ligase, subunit 1 OS=Bacillus weihenstephanensis GN=dltA5 PE=4 SV=1
---------------------------------------------RLWFESLRTVFHEVNGQPK--TDLTEEEVKRLIQTEMPFDLGEGPLIRTSILQVG
EE-EWILIISDGWSMGVWMAFYEKTTDG----KVPVQYPRPAIQTHDGSLVLPSSLHDLLAAYQSFLSRYTGQEDILVYRANLSGRPTFKIVEVVQPER-
--STSHSPIFQTMFILQNMKQE------------FPVLSGMIESHSPIARMAGHFEKWLHEVSHYPLSMLLLETWNDVVDQTYGVMVSLLG-ILKAGGAY
VVLDPLY-PKSRLEYMIEDAVV-TAEGQEGLFEQVEMVRLEEVIEYRSLMNMVSWHQEVYRITAEDRATAGANERDWLIDSRITPILPGKTDFIITGGDQ
L---VTTD--VGVTTGTPSIGHLQLVPSGVIGSL-------ARGYANRPDLTKETGDKASYLSDGALQFHGRIGFRIELGE-IEAAHSSVKEAVVLVVVG
EGSVQ----E----WREHLQTH-LPNYPTNFILKA--------LPI-------PSKLSTENT-FHARTPLEELIASVWSQVLGIENIGVQDSFFELGGHS
LLATQVVSRLQEVFQIKLPVRELFEYSTVEALAKRLDQL-----------
>tr|A0A060DWS5|A0A060DWS5_AZOBR Uncharacterized protein OS=Azospirillum brasilense GN=ABAZ39_27195 PE=4 SV=1
-----------------------------------------LDARPVIAVPAGD--------------AAPGRFDALLDRLETGGLRPAALVQVWRADVG
PGEL---------DAMVYPLLGVIRSLARRGAAVRVVAA------LAGDGGPALFAALPALFG-SLVKELPGWSGQTIAVTGPEGAAPGELAGLLDRELR
DRGPLAAEILVEGERRVRRLRETVVPAAA--LPAALRSGAVTVISGGLGGLGRIFAEHLALGSGATVVLLGRSDPDAERR---LWLEELR----GRGASH
HVK-ADVADPVQTAAAVA-EVRRRFGRIDGVLHAAGVVRDGSLLSRTEEDVAAVFGPKALGAVNLDAAIGDAPDVFVLFSSLA-GQAGNRGQAAYAFANR
FLDGFADWREEQRRGRTLSLSWPLWDGGGIALTPVARALAREAGLAPMSSEDGLRAFEAALASASVAVLAG-DAARLRAFL-----------DRVGDGAG
GDG-----------GETALAAAT-PAAPVRAEDVA-----------ERAEAWVRAFLAEAL-----KLPPG--------------RLGTDQPFEQFGIDS
ILVATLTGQLRKRFG-DLPETLLFEHPTIGRLAGFLAAE-----------
>tr|L8JSV9|L8JSV9_9BACT Malonyl CoA-acyl carrier protein transacylase OS=Fulvivirga imtechensis AK7 GN=C900_01926 PE=3 SV=1
-----------------------------------------GSEQAGAVVSQGDNYQKVSDSAYYCRLNNGGDIQKVLNGVP-KSDIPLTLIYTWAKDQK
ETGI---------HT----LFNLFKAIKEFNHPVDVI--------LTGHYDSTCWDYSWIGFERSLKLLLPD-VRLSLLYTDSSSHTPQQ--------LL
DAAQQPGIIWYKGQRFALSFEPCELNKTT--QEPVLKKNGSYLITGGCGELGFRFAHYLAREYQAKLILLGRRSLTPGIR---QKVDELK----KAGAQV
HYAAVDISNRE---ALAL-WAGKLPFDLSGVIHAAGVESVQPFYEKTADSINSVLHPKSVGTVLLDEMLDHQRDFVCYFSSSA-ALLGDFGSCDYAIANR
FQMAYAYHRQQKGNGRSLVINWPFWKEGGMGKGDAEEAFLKSSGQEMLETAEGIAIWHDIIRSDQALVMKG-KPTRVEQFL-----------GRIYEAKK
PVE-----------TVERQQNAHIKGWKVQYQDLSP---------KECVFADLVKLVSSSL-----KIPAE--------------KLDGITNLADYGFDS
ISLATFAKRLQEHFSLAVTPALFFNYATIGKLSEYFTGE-----------
>tr|A0A023BQK7|A0A023BQK7_9FLAO Uncharacterized protein OS=Aquimarina atlantica GN=ATO12_04945 PE=3 SV=1
-----------------------------------------NTNQAKAIVFQEQKYEKVSENFYHCRSNNVLDIQKVLNDVNDKSNKSIGLIYTWAKNTK
EKGV---------HA----LFNVFKAIKRFDNPIDVT--------LVGNYDSTCWDYSWIGFERSLKLVVPN-SKISLLYTDSSGSISQQ--------LL
DAIQHPGVIRYKDERFELSYKPFDLDSTV--KTPVLKKNGSYLITGGVGKLGFELARYLAKEYQAKLLLLGRRPLVSGIQ---EKMDQLK----QEGAKV
HYYSVDISNRK---AITS-WAKNIPFNLSGIIHAAGVEGSEVFYEKTTKRINEVLQPKSKGIIVLDEVLNQQPDFVCYFSSSA-AMLGDFGSCDYAIANR
FLMAYAYYREQKNNGKSIVINWPFWKDGGMGKGDFEQAFLKSSGQEVLETPEGVTIWDDIIKSNQTLVLKG-KPNRIKQFL-----------DRIYTTKL
LDQ-----------LPFNVQNAHMKGWKIQYQDLSL---------QECVYADLIKLVSMSL-----KIPSE--------------KLDGVTNLADYGFDS
ISLTTFAKKLGTHLFITVTPAIFYNYSTIKKLSDYFVQD-----------
>tr|A0A023XMC6|A0A023XMC6_BRAJP Polyketide synthase OS=Bradyrhizobium japonicum SEMIA 5079 GN=BJS_00720 PE=4 SV=1
-------------------------------------------------------FVQRGPRAWTANERDPQDFRRLLAQLA-ETEALPGVVYLWGLDAP
SINLTFRRLKSASERGALAILHALVEMRSKRPVGRLWFVTTNTQSPAGQWPVDPAQAPLWGLGRTIAIEHPGLWGGLIDMQLG--D-RGFDANLLAAELL
DPDGETQIALSTRQRYVPRLVEQSMA-ELPARPPVIRTHATYLVTGGLGMLGHSVARWLIAKGAKHLVLTGRHASPEVAR-------ELFNNAELNAADI
QVVAADISREEDVKRLLQT--IKELPPLRGVVHSAGVLDDGILAQLDWDRFAALFEPRVYGGFLLHEHTKSLEDFFIL-KSSLLSLLGSAGQANYTASST
FLDSLAMHRR-VTGLPAMVINWCAWSEGGLATLSRGEAMLSSWGMKFVSPDLGIRLFDLMMRRNVD------------------------QVAVVDADWP
TFVSKVGMPRFLSLVNTAVEPRRPG----HVALASTAGRKANG---------------------KSREQLSRRLHQQIREEGFVEDIDPDLPLNEIGLDS
LMSVSLSNSLERKFGIPVPIAQLIRGPTINQLIAS---------------
>tr|V6JQ84|V6JQ84_9ACTN Uncharacterized protein (Fragment) OS=Streptomycetaceae bacterium MP113-05 GN=N566_27610 PE=4 SV=1
------------------------------------------------------------P--LTEAGVPVESFAALTGAVS-TGMTLPVLVALDGSDAP
DGLPRAARETTAHA---LR-TARTWLADDRLAGSRLAFVTRTAVGTGSDRPGDLAAAPLWGLLRSAQSENPGRFA-LVDLDEQ--P-DS--VLALPAALD
TR--EPQLAVRGGQVHAARLARVPVPA---DPAPAWDPDGTVLVTGATGALGGPVARHLVEHGVRHLLLLSRSGTASERGA------ALRDELAALGAHV
TLAACDAADRDALAATLAD--VPDAHPLTAVVHLAGVLDDGVVSALTPERLDGVFRAKVDAALHLHELTRDTPAAFLL-FSSSAATFGAPGQGNYAAANA
FLDALAEQRR-ADGLPALSLAWGAWEQGMAGRLDTDRSRMARGGVLALSETEGLALLDQTLHSADA------------------------ALVPVRLDLA
AFGP-----ELFRLVRRSARRATAAT-----------GEQAGPSLAQRV---------RGLDAAGSRTAVLETVRAATAAVGSGEDIAPDAAFLELGLDS
LTSVELRNVLAAVTELRLPATLVFDHTSPLDLADH---------------
>tr|W5U3K4|W5U3K4_9CYAN Polyketide synthase OS=Moorea producens JHB PE=4 SV=1
DWLYEIAWRPKDIDASDVDISTTWLIFADQGGFGETVGKAVPKEHRVLLISRGSSYEQLQANHYQINPAQPQQFQRLAQQVESLTATSVIVVHMWSLDTP
AVDGQTFPLDVTLENGCGSVLHLLQALVKAELSPRLWLLTQGTQPVGKEKSLRIAQSPLWGLGAVIAQEHPELWGGIIDLEPSQDLSYQEQSLMVLKQIL
RPEGENQLVLRDRQTYVPRLI--HQQQSQLASSPLQKPDSTYLITGGLGSLGLKVAEWMVDKGARYLVLVGRSQPNPASE----IIEKLE----EQGVMV
VLEQVDVSQEAQVRDCLNRIQVSL-PPLKGIIHGAGVLEDGVLLHQDWAKFAKVMKPKVEGAWNLHLLTQDIALDLFVLFSSATSILGTPGQGNYSAANR
FLDSLSHYRR-QQGSPALSINWGPWAEMGLAAGVG--KRMTMLGIEPIQSPQGLQILEQLLAQDVAQVVLPVEWSTLKQRLPVEL---------------
---------------PLFLSEV---------ITTETLPPQGDGENDNSGIFDQLLAS--------TTAQREELLKDYAKALGISREIPVESNLMDLGTDS
LMIVEVLNSCKKDLKITLYPREFYERPTITALAEYLALE-----------
>tr|W5U986|W5U986_9CYAN Polyketide synthase OS=Moorea bouillonii PNG5-198 PE=4 SV=1
DWLYQIAWRPKDVDSSDIDISTTWLIFADKEGFGER--------QKVLLISPGSSYEQLQPNHYQINPAQPQHFQRLAQEVESLNATSVIVVHMWSLDTP
ALDRQTFPLDATLENGCGSVLHLLQGLVKAELPPRLWLVTEGTQPVALEKSLQIAQSPLWGLGAVIAQEHPEIWGGIIDLEPSQDLNYQEQSLMLLNQIL
QPQGENQIALRDGQAYVPRLI--HQQQSQPPALPLQKPDSTYLITGGLGSLGLKVAEWMVDKGARYLVLVGRSQPNPASE----IIGKLE----EQGVMV
VLEQVDVSQEAQVRDCLNRIQVSL-PPLKGIIHGAGVLEDGVLLHQDWAKFARVMKPKVEGAWNLHRLTQDIALELFVLFSSATSILGTPGQGNYSAANG
FLDSLSHYRQ-GQGASALSINWGPWAEMGLAAGVG--KRMAMLGIEPIQAPQGLQILEQLLAQDGAQVVLPVEWSKLKERLPVEL---------------
---------------PLFLSEV---------ITTETLPPQGDRENDNSGIFDQLLGS--------TTTQREELLNDYAKALGISREISGSSNLMDLGADS
LMIVEVLNACKKDLKITLYPREFYERPTITALAEYLALE-----------
>tr|A0A0Q5T2U9|A0A0Q5T2U9_9BACL Beta-ketoacyl synthase OS=Brevibacillus sp. Leaf182 GN=ASG16_14595 PE=4 SV=1
--YYKSVWMEETLPTSDQETDDNTIIVADTAKWHPH---LLEKLQRLIMVEIGTHSLQVTHDHFKVA-RTYEDIAGFCSQL---DISSLDQILFMAPTTH
DLSESWKEFQSSMNQTAGSLLLFTKALHM--TGKKEIDVALITQNAQAVQMAVAICNMLVGLGKSIRQENFCLNIRNIDCSSD----NLEL-DLLLAEIQ
RRSTRYSVALRQGRRYIEVIEKADISGTQED-ETTIGAGDVFLITGGLGQLGTEVCKYLSQKNKVKLIVLGRTMKEAWIRE-QSDKDLVNKMVEALGSVL
DYQCVDICDESEMKRLVQNIQETH-GQLNGIIHCAGVGVGDIEFGMSEQEFERRHAVKTYGSWLLYTLTKEMNKGFTMFFSSAVSVTGGRGSLSYATGNA
FLDGLAETIK-RQGKKVISINWATWETTA-SKLSMQE---ERHVFRFLSTHQALQALDHILH-----------------RQMFR---------TIVGKLN
--HAN-----------------------ELLELEHVWPFLLADEVKQELFKETAKPGRTSVTLKEKDTATQKELAQLWAEVLGLNAISLFDTFHQLGGDS
IHAAQLYKQWNEKYPGTLHVADIYMYPTIYEMANYLESK-----------
>tr|J3AWZ5|J3AWZ5_9BACL Beta-ketoacyl synthase family protein,phosphopantetheine-containing protein OS=Brevibacillus sp. CF112 GN=PMI08_04780 PE=4 SV=1
--LYQVAWKEEALPATDQQTACDTVIVADTAIWRPL---FAQQHQRLVTVELGARSAQVAPDYFQVS-RTLDDIAAFCAQL---DLASLAQIVFMPPARA
ALPESLAAFRSAMDQTAGSLLLFAKALAT--TGKNEIDVVLLTQNAQAVQPGDAACDMLGGLGKSLRQENYGLSVRHIDISPD----GFAP-EPLFAELG
RKGTDYSVALRQNRRYIEIIERAKQTGAQED-SFAIEAGDVFLITGGLGQLGTEVCKYLSQKNKVKLIVLGKTMRETWLRE-SPDISLADKIVEALGSTL
DYHCADICDEAQLQRTVQAIRQTH-QRLAGVIHCAGIGVGELESALGEAEFARRHAVKTDGSWLLYTLTQEIDTGFYLFFSSAVSVTGGRGALGYATGNA
FLDGWAEAIR-RQGKKVFSINWATWEETA-ERLSMQE---ERHVFRFLPTHQALQALDSILR-----------------RQMFR---------TIVGQFN
--QAN-----------------------ELLELAHIWPFRLADEVKKDVFRQTAKPGRVPVTLKEQDTATQKELAQVWAEVLGLSSISLFDSFHQLGGDS
IHAAQLYKQWNEKYPGTLHVADLYLYPTIFEMANYLDGK-----------
>tr|A0A0E4H817|A0A0E4H817_9BACL Beta-ketoacyl synthase family protein,phosphopantetheine-containing protein OS=Paenibacillus riograndensis SBR5 GN=PRIO_1742 PE
--YYTTEWVEESRLPAGSGAARETVIVADTALWEAQ---LPGKLRRCILVEIGRPYRKINAEHYHVS-NSVEDFSALCGEL---DISALEQILYAAPSRE
GLPDSLKEFKESFNQTVMNLLYLVKALQA--ANTKDLDIALITRNAHVLQPMDTGSDTLYGIGKSILQENRSFHVRHIDISNE----PADL-EALPAELE
VPSAQYSVALRHGRRYVEVIKRADIAEQAGE-AIAIEAGDTFLITGGLGLLGIEVCKYLSQKNRVKLIVLGRTARESWIMD-NEDKQLLKKIIEALGFTL
DYHCVDICDEAQLRRTVEQIRQDH-GSINGVFHCAGVGVGDIEFGMSGQEFEQRHAVKTYGSWLVYNLTQEFNTGFTLLFSSAVSITGGRGSLAYTAGNA
FVDGLAETIR-LQGKNVMAINWSTWEATA-SRLSLQA---DKHFFEFLSTHQALQALDLIIR-----------------RGMFR---------TIVGKLN
--VQN-----------------------KLLELENLWPFRLAGEIKQALFPKTRQEERTSVTVKEPETATHRELAQVWADILGLTTISVFDSFHQLGGDS
IHAAHLHKQWNERHPGTLDVTDIYRYPTIHEMAGYLDSQ-----------
>tr|A0A089M5F9|A0A089M5F9_9BACL Beta-ketoacyl synthase OS=Paenibacillus graminis GN=PGRAT_08135 PE=4 SV=1
--YYKAEWVEEHRQTANTGAARDTVIVTDTALWEPQ---LFRKIRRCILVEIGRPYQKITGTHYYVS-NSAEDFSALCGEL---DISALEQILYAAPSRD
GLPDSLEEFKDSFNQTVMNLLYLVKALQA--ANSKNLDMALITQNAHVLQPMDTVSDTLYGIGKSILQENRSFHVRHIDISHE----PADM-DSLLAELE
VPSADYSVALRHGRRYVEVIKRADMAEEASE-AAGIEAGDTFLITGGLGLLGIEVCKYLSQKNRVKLIVLGRTARASWIME-NEDKQLLKKIIEALGFTL
DYHCVDICDETQLRRTVQLIREHH-GRINGVFHCAGVGVGDIEFGMSEQEFEQRHAAKTYGSWLVHQLTEPFNTGFTLLFSSAVSITGGRGSLAYTAGNA
FMDGLAETIK-LQGPNVMAINWSTWEATA-SHLSLQE---DKHFFEFLSTHQALQALDLVIR-----------------RRMFR---------TIVGKLN
--VRN-----------------------KLLELENVWPFRLADEIKQTLFTKTHREEQTRVTVKEPETATHRELAQVWGDILGLASISVFDSFHQLGGDS
IHAAHLHKRWNERHPGTLDVTDIYRYPTIHEMAGYLDSR-----------
>tr|A0A069JM55|A0A069JM55_9ACTN Uncharacterized protein OS=Streptomyces sp. NTK 937 GN=DT87_01010 PE=4 SV=1
--------------------------------------------------------------GARFRTGHKEDLEALLEASARLGLDAV-VEARWHARPE
DDGARTAAAALTEAPAAWGPLL--RAAAQLPAPPAVVLATRAAAAVTGDE-ESVAHAALTGVAESLAQSRPRLPVLLVDGATD------D---DLLTECA
LRGTG-QVAHRDGTRLVRGLRPLDGASIPPVPRRVLRAGGSYAVVGGLGGVGAHLTQHLLRQFGARVLVLGRDAAEPGTARGG-IRAHLADQAGLEGAAF
RYTPLDATDVPALRAALDRAEADWG-PLDGLFNLAGSVAEQLELLPGGETAPQVPETRLRISHALDEALTGRT-TPLVVFSSVNGFFGGAGFTEYAGACA
YLAAHAAWSA-RRTGARLCLDWSMWKQVGMAAGSAVTELAGRRGFATIGPAQGLASLHTALDAAEDRVLIGLS----PAGEAVAG---LLPFTASAFELE
ADGTHD-----PATIAALT-----GV------DVSRIRRTSTGAGDRAAV---------------GAAHTE-ALLDVFRDVLGDGQVGEEDNFFAAGGDS
IRAIQVVARAAE-RGFRFSPLDLFEHKTAAALLA----------------
>tr|D3P0F1|D3P0F1_AZOS1 Polyketide synthase OS=Azospirillum sp. (strain B510) GN=AZL_a05990 PE=4 SV=1
--------------------------------------------------------------TASYDPADPEDIARVVAAAARYGLERV-ICGRFAGTPA
DTAADAALATLAEARSRWKAIC--RAAEALEPAPVVLFATSGAFCADGSE-TRIGQAVLTGLSATLGQEHPRLRVSLVDGATT------LA-AALAVED-
-GETI-RVAYREGVRLVPRLRPVETAAIPEQPSPLLRKGGRYLVIGGLGGSGAHLCRHLLTAFSANVLTVGRSEINHAGGRAQ-AFAHLRAHAESTGGRI
AYARADATDPAALARVVSTAETADG-AFDAVFDLAGSVSERLSGTSGTDGTDLAFAARIRVLHAIRTAC--PS-RPVIVFGSVNGFFGGAGFADYSAACS
YQAAFAASAA-ARGDGAVCVDWSMWKATGMAADADLRALARRRGFDTLAPRQALGSLHVALAEAAPHLLVGLY----AGGTMVMP---HLPPRRIRTRIE
ATGTTD-----AAAVARAV-----GV------PEDAVRCRSRGAAAEAHV---------------PPEQAD-ALLAIFRDVLVRPELGADDNFFGNGGDS
IRAIQVVARAAA-IGISFKPLDLFEHKTVRTLLS----------------
>tr|L9PII9|L9PII9_9BURK Polyketide synthase OS=Janthinobacterium sp. HH01 GN=Jab_2c35360 PE=4 SV=1
--------------------------------------------------------------RASYRPCVAAELSAVLAADELLDLDMV-VEAHALAPPQ
DDDAAVAGVALAAAHGHWEALF--AAAELLPQAPALVLATSAALAVDGSE-AGVAHAALPGVAASLAQSRPQLRVALVDGVGA------DA-AALLRERP
GAGIS-QVAYRGGARLTPMLRPLPAAQTPLQPRHILRPGGRYLVIGGLGGVGVHLCLHLLRNFGARLLVVGRGRLEQNPPRAQ-ALAYLAEQAAVDGAGI
DYRQADPADADALPRALRAAAQDWGAPPDAVFNLAGSVAERLAALEADGGAGAALRERIALLHAVERALAGGS-VPVVTFSSVNGWFGGTGFVEYAGACA
YQAAYAGWQA-RRGARHLCLDWSMWKQVGMAAEAALVALARRRGFDSLSPAQALASLHLALEHGAPRQLIGLY----PSAPAVLQ---LLPPSLVRHRVE
AAGAVA-----AAQVAAAL-----GV------APELV-RCSHAPRPAAAL---------------PAAHAA-ALLAVFRDVLVRPELDLDDNFFASGGDS
IRAIQAVSRAAD-RGLTFSPLDLFEHKTVAALLG----------------
>tr|M3BCW6|M3BCW6_STRMB Beta-ketoacyl synthase (Fragment) OS=Streptomyces mobaraensis NBRC 13819 = DSM 40847 GN=H340_26666 PE=4 SV=1
-------------------------------------------------VLPDAG----AADVVVLPAGTEDAGGDAAGAARERTHRVLADLQSWLADER
F---------------AGSTL------------VVVTRGAA---PAGTTEVTDLAGAAVGGLVRSAQAENPGRIV-LVDTDGTD----ASLA-SLP--RA
LAAGEEYLAVREGELSVPRLARVPATVRTADADETRDGHGTILVTGATGALGALVARHLVAEHGRHLLLASRRGPDA--PGAQELGAELA----ESGAEV
TFAACDIADRDRLAALLDSVPA--EHPLTAVVHVAGALDDGVIGSLTPDRMDTVLRPKADAAWNLHELTRGLDLSAFVLFSSVAGALGVPGQGNYAAANA
FLDALAHHRR-AAGLPATSLAWGMWADSGMAGGLADVRRMARSGAGALSAKEGLALFDAAFTGSEALLPVALDLRLLADPGEL--------P-PLFRGLV
RTT----------------ARRTRSAQ--------E---PSAGTGD---LLARLAA--------TPAAERRLLTEVVRAQVLGHDGVDADRSFNALGFDS
LTAVEFRNRLNAATGLRLPAALTFDHPSSRAVADHLWDE-----------
>tr|D9WQ71|D9WQ71_9ACTN Modular polyketide synthase OS=Streptomyces himastatinicus ATCC 53653 GN=SSOG_05745 PE=4 SV=1
-------------------------------------------------VVMDGT----APDTVLIPF-LPDGGDDLVADAHAATHRALGLVQEWLNGGR
P---------------DGARL------------VLVTRGAVA--AAGDTEVADLVNAPVWGLLRSAQTENPGQFV-LLDVDGEV-----SYP-AIA--AA
LDSGEPEIALRAGAAYAPRLAWVEAP----ADENTLDPEGTVLVTGATGGLGRLVARHLATAHGRHLLLTSRSGPAA--EGMAELVAELA----TLGAEA
AVVACDAADREALAGLLAGIPA--DRPLTAVVHTAGVLDDGVIDMLTPERVDRVLRPKVDAAVNLHQLTRDLDLSAFVLFSAAAGTIGGAGQGGYAAANV
FLDALAGHRR-ATGLAAQSLVWGMWAERGMGGRIADLKRAARGGVLPLSAEEGLALFDAARTVTEAVLPVRLDLAALRSAGEL--------L-PLYRGLV
RTP----------------ARRADGGG--------PAVESAAETDT---LAQQLAR--------QSEAQQETVLDLVRRQVLGYEQVGAEQAFKELGFDS
LTAVELRNRLNTATGLKLTATLVYDYPTPVALARQLRHE-----------
>tr|A0A0L8L359|A0A0L8L359_9ACTN Type I polyketide synthase OS=Streptomyces resistomycificus GN=ADK37_26615 PE=4 SV=1
---------------------------------------------------PAGR----APRHLVLCPD-PGTRPDLLAAVATADKGVLECVQRFLAEDA
L---------------APCTL------------VVLTRRAVD--TGAGDSVESLPGASVWGLIRSAQTEHPGRFR-LVDIDDEE----TSWA-RLT--DA
LALGEDQLALRDGSCLVPRMTPAQPADHRLEPAGGGFGGGTVLVTGGTGGVGSLVARHLVAEHGRSLVLAGRRGAAA--DGARELVADLE----AAGAVV
RVVACDIADRAAVADLLADMPP--RYPLTAIVHAAGVLADGTVESLTAAGIDRVLHAKAGGALTLHELTKDHTLSAFIHFSALAGTLGTAGQANYAAANA
FLDALAAQRK-ASGLPGTSLAWGWWEQSGMTEDLADLLRLRRMGIAPMPTPEALALFDAAHALDKPLLPARVDVAALRGGDEL--------P-PLLRDLA
DGG----------------RPR-SRAD---------T-TKDGGFAG---LPARLAA--------LPGDEARAVLDWVRDQVLGHAVVDTEQAFTQLGFDS
LTSVELCNRLAAATGLRLATTLVFSYPTPRELGEHLHDL-----------
>tr|A0A0Q1CX37|A0A0Q1CX37_9ACTN Polyketide synthase (Fragment) OS=Frankia sp. ACN1ag GN=UK82_23620 PE=4 SV=1
-------------------------------------------------IEAGTA----VPDLVVLPLG-ASDIVDVPAAARAATQRALELLQTYLSDRR
L---------------DTTRL------------AVLTSGAVS--VAG--EDVDLTTAPLTGLLRTAQSEQPDRIL-LIDLDGDP----DSRA-GLPAAAA
LASGENQLALRRGTAHTPRLVPAAAAAAAATPHWDLDPDGTVLITGGLGTLAHHLAHHLITHHHRHLHLTSRTGPDH--PHAQTIRTELE----NLGATI
TITATDTTNPHQLQHLLDTLDP--HXPLTAVIHTAGTLDDTTLTNLTEDRLHTVLTPKIDGAWHLHXLTRHHPLKAFVLYSSIAAITGNPGQANYATANT
FLDALAHHRH-AHGLPATSLAWGLWNDSTXTENLADRARITQSGLRSLAPADGLALFDAAGTLHQPLLPAALDVATISATDGV--------P-PLLRGLV
RPG----------------RRGAQGAA--------A---SRADAAA---LRGRLAA--------APDEQREILLEHVRQEVLGHGTVEAERDFGELGLDS
LTAVELRNRLNTATGLRLPATLTFDHPSAAALAAYLAEQ-----------
>tr|Q0RTS6|Q0RTS6_FRAAA Putative Type I modular polyketide synthase OS=Frankia alni (strain ACN14a) GN=FRAAL0346 PE=4 SV=1
-------------------------------------------------VEAGAA----VPDLVVLSLGPAPDLPDVPAAARAATERAVDLLRAYLSEQR
W---------------DATRL------------VVLTSGAVS--VAG--EDVDLTTAPLWGLVRTAQNEHPDRIL-LIDLDADP----DSRT-ALPAATA
QATGDNQLALRRGTAHTPRLVPATTPDAADAAGWNLDPDGTVLITGGLGTLAHHLAHHLITHHHRHLHLTSRTGPHH--PHATALRTELE----NLGATI
TITATDTTNPTQLHHLLDTIPP--AHPLTAVIHTAGTLDDTTLTNLTPERLHTVLAPKIDGAWHLHHLTRHHPLKAFVLYSSLAGLVGGAGQGSYTAANT
FLDALAHHRR-AQGLPATSLAWGLWDDSTFTENLADRARIAQSGLRSLAPADGLALFDAAGTLRQPLLPAALDVATISAADGV--------P-PLLRGLV
RPG----------------RRGAQAGT--------A---SRADAAA---LRGRLAA--------AADEQREILLEHVRQEVLGHDTVEAERDFGELGLDS
LTAVELRNRLNTATGLRLPATLTFDHPSATALAAYLAEQ-----------
>tr|A0A0N0YHA6|A0A0N0YHA6_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. NRRL S-4 GN=ADK82_27950 PE=4 SV=1
---------------------------------------------------------------------------------IDEHGSLSGVLSLLSFDER
PHP-----VHSMLPSGSFAVLSLLRAMTW--LELESTRTAVSVRR--SDVLARPVQAQAWGLGRVASLEHPKVWGGLVDL--PEEVDARALER-LVAVLA
GTNEDQLAVRGTGVLARRVLPAPPDEA---APARSWKPSGTALVTGGTGALGGHVARWLATDGAEHVVLMSRSGDKAPGVTDLVA------ELEKLGSRV
TVAACDVTDRAAVAGLLERLSS-AGDAVRTVVHAAGVGRLAPLAATDDDVFADIAAAKVAGARHLDELIDHELDAVI-YFSSVSAVWGVGDHGAYAAANA
FADALAEQRR-AEGVPALSVAWGPWAGGGMVSEDA-KILLDRQGVRLIQPASGIAALRQADHDDTTVVVADVDWERFAP---------------------
------IFTPLIADIPQVAAVLGETAAE------PVGGTDTAL-----ALGAELTVLSE--ADRA-QL-LLELVRGHAATVLTPKAVEAGRAFRELGFDS
LTAVELRNRLNTATGLRLPATSVFDHPTPAALARHLQAE-----------
>tr|A0A0F5AJE0|A0A0F5AJE0_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. MUSC164 GN=VT50_04255 PE=4 SV=1
---------------------------------------------------------------------------------GAPDGAVGGVLSLLALDED
PSP-----GHAVVPQGLALNLVALQALVD--AGVEATRGAVSVTG--SDTLHSAAQAQMWGLGRVAGLEHPRLWGGLVDL--PDTFDERAAAR-LSGVLG
GGAEDQVAVRTSGVFTRRLVRATA-PR---TTARPWSARGSVLVTGGTGGVGSQVARWLAGAGAEHLVLTSRRGPEADGAAELRD------ELAALGAEV
TIAACDTADREALAAVLAAIP--ERYPLSAVVHAAGVLDDGVLDAMSVERVAGVLRPKVDGARNLHELTKDLLSAFV-LFSSLAGAIGGAGQGSYAAANA
YLDALAQQRR-AQGLAATSVAWGPWAEGGMAVDGALEERLRRGGMAAMTPELAVKALQQADLQETHLAIADLDWERFVP---------------------
------SYTRLLDEVPEARRILEAATG---------GATATQFETGGSELRERLAGKSE--TEQE-RE-LLDLVTTQVAMVLSVESVESQRAFRELGFDS
LTAVELRNRLDAATGLRLPATIVFDHPTPVALARRLRTD-----------
>tr|D3DDG1|D3DDG1_9ACTN Short-chain dehydrogenase/reductase SDR OS=Frankia sp. EUN1f GN=FrEUN1fDRAFT_7833 PE=4 SV=1
---------------------------------------------------------------------------------GVVAADIRGVLSLASMDTT
ALG-----THPVLPTGLALTVALLQALGD--VGVTATSGAVSTGAGPSGQAQVLAQAQVWGLGRVAALEMPGRWGGLVDL--PGALDPRVAEG-LAAVLT
GTCEDQVALRPAGLFARRIVRARGGPGA-VADGSRWRPRGTVLITGGTGALGSEVARWCATEGAERLLLTSRRGMAAPGAAELAA------ELTRLGAEV
VVAACDVTDRDALAEIIAAVP--ADQPLTAVVHAAGTGDGAVLERTTPAELAAVVAAKTTGAAHLDDLLAGQLDAFV-LFSSVAGIWGNPGQGAYAGANA
WLDALAERRR-ARGLPATSVAWGPWAGAGMADDPRVRARTERHGLPPLVPEEALRALAQVGGGEPGVVVARVDWERFVA---------------------
------AFPRFVDEIPAARDAASRSRDGRSRSSAGLPSAGLPASPRSVGLRDRLASVPA--SGRH-RL-LLGLVRSEVAAVLSPEDIPADRAFTDLGFDS
LTSVETRNRLAQATGEQLPAVVVFDHPTPDALARHLLTL-----------
>tr|A0A0M0T6H8|A0A0M0T6H8_9ENTR Polyketide synthase OS=Xenorhabdus sp. GDc328 GN=AFK69_16885 PE=4 SV=1
EWLYGEIWQDALLPNKSQSDVKMALCFVPDIEWCEPLRHMNIDEKAVRFVLSGDNYTTAN-NVITLSAGEVSHFERLFNELKENQLQPDSIIFAWPLSGS
DE------V----KNTWFSAITLLQAWTT--VGNMCDF------RLLLVNTEQPESNMLNGLVKVITQEVSKCHPRLVQINPTESI---EKNCEILTEEL
LATGERFIVRRKEGCSKQAYERIA--INPLKEHSLLKPQGIYLITGGLGDLGLLFAEYLLKEYRATVILSGRRELPDQREWKQEILQRLDKLSDLGTGNL
AYYAANVADKSAMQRLLTTISKQYG-ELNGIICAAGVTEGNSINRITLDACLPQLETKVEAYKILAELTENQPDFCLLCSSIA-VVLGGLSFSAYSSVSA
FADSFAKQQS-KKGKPWISVNWDGWVFERNDSGDALGSSLSQ---LLIEPDEGIK--------------V-LER---VLQSPLRD-------QIIV---S
TGDLDKRFAQ-------WV-----GS---YLKTFDINKV---NQSQRKTI------S---------KAQIVETILSVWKDFLKIAHINREDNFFELGANS
LDLVQVNKRLTDALNIDISVVDMFSYPTSDLLADHITNQ-----------
>tr|A0A077PIN2|A0A077PIN2_XENBV Polyketide synthase involved in xenocoumacin synthesis OS=Xenorhabdus bovienii str. kraussei Quebec GN=xcnF PE=4 SV=1
EWLYTEAWEDISLPDETQSDIRVALCFVPDIAWCQPLNSLKLEEKSIKFVLPADAYTSAE-NVITLVPGDKRHFGKLIDELKQDALLPDSIIFAWPLSGQ
SD------L----ETSWFSVITLIQSWTT--SGSMTDF------RLLLANTKQPEHTMLNGLVKVITQEVSKCHPRLVQISPLESI---ERQCEILTEEL
LATDERFIVNRQTGRSTLAYHKLK--AGLLKENTLLKNEGVYLITGGLGDLGLLFAEYLIKEYGAKVILSGRRALPGKHEWKHEILQRLDELSELGKGEV
AYYSSNVSDKHEMQALLDAIEEQYG-CLHGIICAAGVTRGNSINKLTLEDCTPQIETKVEAYQILAELTENKPDFCLLCSSIA-SVLGGLSFSAYSSVSS
FADAFAKQQN-SQGKPWISVNWDGWVFERNNSGDPIGSSLDQ---LLIEPDEGLK--------------I-LEC---ALQSPLRG-------QLII---S
TGDLNKRFEQ-------WV-----GG---HLKPFKLNEF---NHSQRAVV------S---------KEQIVGTIVSVWQDFLKVTNISRDDNFFELGANS
LDMVQVNKRLTDALDMDFSVVDMFSYPTSELLADFIMNQ-----------
>tr|A0A0A8NZD0|A0A0A8NZD0_XENNE Polyketide synthase involved in xenocoumacin synthesis OS=Xenorhabdus nematophila str. Websteri GN=xcnF PE=4 SV=1
DWLYGEIWQDALLPDKNQSEVKTALCFVPNMEWCEPLRYLNVDEKSIRFVLSGDDYTSVN-NVITLAAGEVSHFEKLFHELKENQLQPDSVIFAWPLSGH
RD------L----KNTWFSAITLLQAWAT--IGNMGDF------RLLLVNTEQPESGMLKGLVKVITQEVSKCHPRLVQINTTESI---ENTCEILTEEL
LATDGRFIVCRDGRCSEQVYERLN--VEPQKKHSLLKQQGTYLITGGLGDLGLLFAEYLLKEYQATVILSGRRELPDRHEWQQNLLQQLNKLADLGRGNV
VYYPANVADKSAMQRLLQTIDKQHG-ALNGIICAAGVTEGDSINRITLDACSPQIETKVEAYKILAELTEHQPDFCLLCSSIA-SMLGGLSFSAYSSVSA
FADAFARQQN-QQGKPWISINWDGWVFERNDSGDALGSSLSQ---LLIEPDEGIQ--------------I-LER---VLQSPLRG-------QIIV---S
TGDLNQRFEQ-------WV-----GS---HLKAFDINKI---SKSHRKTI------S---------KDQITETIISVWKDFLKITQINREDNFFELGANS
LDLVQVNKRLTDALDIDISVVDMFSYPTSELLADYITSQ-----------
>tr|A0A022PKQ8|A0A022PKQ8_PHOLU Polyketide synthase family protein OS=Photorhabdus luminescens BA1 GN=BA1DRAFT_01898 PE=4 SV=1
QWLYTEQWQPIELPTETEQ-ANNIVCFVPSLAWCNVFKRFNQEGQKLKFIVPSPEYYVDG-QVIGVTPGDKNSFNKLMAELAHSCFSPDSIIFAWPLSGT
KD------I----MTSWFAVILFLQSWGK--SGHLSEF------RLLLATTALSEHSLLNGLIKVIAQEVTKCHPRIIELDTDESI---EAACDILAQEL
TASDMRFIVKRQQARFEKRYQQLE--NNEQAKKQPFKKQGVYLITGGLGDLGLLFAEHLVTQYGAKVILSGRRDLPRKAQWGDKLIDRIHQLSLMSEGDI
DYYAADVCDRQEMETLIGHIEAQYG-QLNGVICAAGVTRGDSINHITMENCQPQFDTKVYSYQLLAELLEHKQDFCILCSSIA-AILGGLSFSAYSSVSS
FADAFAKQQN-QLGKPWISINWDGWVFERKDANDAIGSSLEQ---LLIEPDEGLY--------------I-LER---VLQSPLEA-------QLIV---S
TGDLNKRFEQ-------WV-----GT---HIRPFTNQSH---SAHSRQIF------S---------KQQIVDTIMDIWQDFLKIHSINSGDNFFELGANS
LDLVQVNKRITEALYIDLSVVDMFSYPTSELLAGFIIEQ-----------
>tr|A0A0N1GBL0|A0A0N1GBL0_9ACTN FkbH like protein OS=Actinobacteria bacterium OK006 GN=OK006_9711 PE=4 SV=1
-----TRWQPCPAA-QQPPAEGSWLILADDTGVAAELAERLGSTVPRVIARRGESFGVEGPGRYLLDPADPRHLARLLDEAFP-DGPPERVVQLSALDAP
A-ITDAGTAEEAARLCCLSTLHLVRALADRPGRAPRLFVPARGSQAAGDSTTHPQQALAWGFGLAVAQEYPELSATLIDLPPT------DGVDALWTQLR
HADDERLVALRESGRLVPRLARTRPDDGG---NGEVTSDGVYLITGGLGGLGRVVAERLVRRGARRLALMSRGEPDGHTA---SWISG----LEEHGTTV
HLARADVADREELTAALDRREA---GPIAGVVHAAGVLDDATVANLTDERVLRVLAPKVLGTTLLTELIPEAESLV--LFASAAGLLGSAGQSPYAAANA
FLDAWAHHLS-RVDRRALSLDWGAWAGVGMVAESGIRAAEGRSGLLALSPQDGGELFERVLATSRRLAPLALDWE-----TLAHDPD-AARTRPILGDLI
TDGADDLVASVFAATTA--R-----DRADRL---------------EAYVRARVQVSEGTV------------------------DVSATTALKELGLDS
LMLVRLRNAFARELGAELPAATVFSASDIRGLARALGE------------
>tr|A0A0M2JL38|A0A0M2JL38_9ACTN Polyketide synthase OS=Streptomyces mangrovisoli GN=WN71_15135 PE=4 SV=1
-----TRWQPRPAPASKDAEDGGWLLLADGTGVADELAARLGESAPHVVARRGDSYATEGPGRYVLDPTDPAQLRRLLDEAFP-DAPPARVVQLSALDAP
P-VDGTATADLAARLCCLSTLHLVRELTDRPGRSPRLFVVTRGSQAAGDSGTGPQQALAWGFGLTVAQEHPELAATLIDLPPT------GGTDALWTALR
DADDERLVALRGAERLVPRLARTRPDDDG---AAARTTDGVHLITGGLGGLGRVVAERLVRRGARILALLSRGTPDADAA---GWIEG----LRERGVTV
LHARADVADRAALTAALARHEA---GRITTVVHTAGVLDDATLANLTEERVLRVLAPKVLGTALLTELVPEADDLI--LFASVAGLVGSAGQAPYAAANA
FLDAWSHHLG-RTGRRSLSLDWGAWTGVGMVAGSGVRAEQGRSGLVPFTPEEGGELFDRVLTSGRRLAPVALDWE-----LLALDPD-TIRTRPVLADLV
TGATDDLVRRVFAATTQ--D-----ERTTWL---------------ETYVRARVEVSGGTV------------------------DASATTALKELGLDS
LMLVRLRNAFARDLGAELPAADVFSANDIRGLARALAT------------
>tr|C9YYI1|C9YYI1_STRSW Putative type I polyketide synthase OS=Streptomyces scabiei (strain 87.22) GN=SCAB_83901 PE=4 SV=1
GWRYQVTFKPLHLTPGTPALTGTWWVVVPAGAAGHPLRALERHGATAV---------PVEIGTTGTDRAG------LAARLGAATAPDGGVLSLLALAEQ
PYADGT-----ALPTGLALTTTLLQALGD--AGINCGAVSVGRSD----ALTAPAQATLWGLGAVAGVEYPERWAGMLDLPSD----LDEAGVRLAAVLA
GLDGEDQIAIRPGVYGRRLVRARPAEETT---ADAFDPDGTVLITGGTGALGAHVARRLARSGARHLLLTGRRGPDTPGAA------ELVAELAGLGAET
TVAACDAADRDALATLLADIPEDR--PLRTVVHAAGLLDDGVLDTLTPERAAGVLRPKMDAALNLDALTRDLDTA-FVLFSSLAGTLGGTGQGSYAAANA
FLDALAEQRR-SLGLPATSVAWGLWAGDSAA-DSA-RERLVRNGLPPMDPELAVTALEQAMGRA--------------------------EPRLVLCDFA
WDR--------FAPAYTALRPSA---------ALRDLPDVRDQETEADSLAARLA-------ALSPQERQEELTRLVATEVAAVAGIDPDRVFKDLGFDS
LTAVDLRNRLSEATGLRLSVTLVFDHPTVTALVDHVRSE-----------
>tr|A0A066Z6A5|A0A066Z6A5_9ACTN Polyketide synthase OS=Kitasatospora cheerisanensis KCTC 2395 GN=KCH_04110 PE=4 SV=1
NWRYRVAWKPLPAA-ERPRLTGSWLLVAPAGAAEDPADALSGHGATPV---------LVEAGHDATDRAR------FAALLRRADGPPAGILSLLALAEE
PHGEGS-----ELPLGLTLTVALLQALGD--LGTDRGAVSVGRSD----RIDSTLQALTWGLGGVAGVEYPQRWAGLVDLPRR----LDDAATRLAEALA
NPDGEDQLAVRAGLYGRRVVHAALGDTAP---ARDWTPEGTVLITGGTGGLGAQIARRLARTGTAHLLLTSRRGAQAPGAE------ALLAELRELGAEA
TVAACDVADRDALAELLAAIPAER--PLRAVLHTAGVLDDGVIDSLTPERAAGVLRPKLDGARNLDALTRGLDTA-FVLFSSLAGTLGGTGQGSYAAANA
HLDALARHRR-DLGLPGTSVAWGLWGGETLAAGAV-AERLIRDGLPAMDPATATTALLRALDHE--------------------------DTNVLVADFA
WDR--------FTRAYTALRPSA---------ALADLPEVRDGADGAEPPALRIA-------ALPPAERDRALLDLVRREVAAVEAVGPDQAFKEIGFDS
LTAVELRNRLAAATGLRLSVTLAFDYPTATALAGHLRAE-----------
>tr|G2PEV3|G2PEV3_STRVO Beta-ketoacyl synthase OS=Streptomyces violaceusniger Tu 4113 GN=Strvi_4158 PE=4 SV=1
GWRYKVSWKPASDL-AEGSLSGTWLVVVPASRAGDEVAGFERHGAGVV---------SLVVDERDLDADV------LAERLRAEVPELGGVLSLLALDEE
PCPGYP-----ALSGGYALTLVLVRAVVW--AGIERGAVSVGRSD----RLTSPTQAMVWALGRAAALELPPLWGGVVDLPES----LDEAVARLAGVLS
AGGGEDQVAVRGGVFARRLVRSAAA-VGE---GISWRARGTVLVTGGTGGLGGQVARWLVRSGAEHLVLTSRRGLEAEGAA------ELKAELEGMGAEV
TVAACDAADRDTLAAVLDAVPEHR--PLTGVVHAAGVTMTASLLETELADAARAVSGKVAGAVNLDELLGDREDA-FVVFSSISAVWSGAEQGVYGSGNA
FLDALVERRR-ARGLAGTSVAWGPWAEEGMVTGDA-GEQLARRGLPAMAPELAIAALERAVAGD--------------------------DGLVTVVDVD
WER--------FAPAFTAVRHSR---------FLSELEEVQRAEAAGAQLRERLK-------PLTEGERDRALLDLVRKHAAAVEMVEPNRAFRDLGFDS
LTAVDLRNRLAAETGLGLPTTLVFDYPSAGTLAAYLRTE-----------
>tr|A0A017TA30|A0A017TA30_9DELT Malonyl CoA-acyl carrier protein transacylase OS=Chondromyces apiculatus DSM 436 GN=CAP_3204 PE=4 SV=1
DWLYAVEWQERPRGTPPPAPAAPWVILADRTGLAEA---IAARGEACVRISPGSGYLRLSDTHREVDPLS------SEQ-LGGVAGRSRGILHLWSLDAP
S-TEAL-----ALDALEGSTVSVLRMLAAP-AEAAREAQALTECPA---APPALAQAPLWGLGQVLSLEHPDLWGGMIDLDGT----SASAASALLDEIC
QPDPDDLVALRGTRHVPRLVRKPEV-SAT---PITFHSDAAYLITGGLGGIGLALAHWLVQRGARHLVLLGRRGLPERPARESLQKAAAIALIASLGAVV
EVVSADVGDRPRMQEVIATFGRDRP-PLRGVFHAAGLSTPELLKDARPETLQAMLRPKVNGTWILHELTRDLPDV-FVSFSSVSSVWGSLGLGLYAAANH
FLDVFASYRR-AAGLPALTVNWGSWSGVGMVSDDM-ALFMAKMGIDSMPPGPSLDVLGQLMASG--------------------------ATRCTVATVD
WRK--------FKPLYEARRVRP---------LVSTLDV-RLGGPAASQLSERLG-------KALPGERRDLVVEHVEGLVARVEVRGLRAGFTAMGMDS
LMAVELKTKLEDSVGQRLPSTLAFEHPTIEALTEYLLRE-----------
>tr|D7C2J3|D7C2J3_STRBB Type I polyketide synthase OS=Streptomyces bingchenggensis (strain BCW-1) GN=milA2 PE=4 SV=1
AWRYDEVWQPLDLADAEPMPPGDWLVVIPARQAGHPLSGLREHGGIRTT--------ELVLDTADIDPLV------LRQHLAPDDVSICGVLSLLAFDEE
PHPEHP-----HLPTGTALTLTLIQTLTTH-PNTTQTATTTHPTD----TLNHPTQAHIWGLGRTTALEHPNHWGGLIDLPTT----PTPHLHHLTTALT
TQHNDDQLAIRDGLQTRRLTRTATT-PSN---PQPWKPHGTILITGGTGAIGTHIATWIATHPHCHLLLTNRQGPNTPHNT------QLHHHLTQLGATT
TITTCDTTNPNQLTNLLNTIPPTH--PLTTIIHTAGINLKSTIADLSAADLAETAGAKATGAAILHELLREHTER-FVLFSSIAGTWGSANQAGYAAANA
YLDALAQHRR-AQGLPAISIAWGPWDGAGMAAGDT-RAHLRRRGLRAMSPDLALAALDRILGHGP------------------------DSAAAVVADVD
WED--------FATTFTARRPAP---------LIDDIPEVRQ-PPSADSLREQLA-------QRSPKEQQQALLDVVRTHAAAVESIDAQQAFSALGFDS
LTAVEFRNRVAAATGLALPTTLVFDHPSPTECATHLRTA-----------
>tr|A9AVG0|A9AVG0_HERA2 Amino acid adenylation domain OS=Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785) GN=Haur_2008 PE=4 SV=1
---QQVVWTQTALAAPSDQALEQWVVIADNNPLADQLLRLLNTANRACVVTTSA-----------------MLNSVLPTISNRYGLSSDEVIAQTNAFEQ
-----------TCYVGALQLLDSIKSILAQPNGLWVVTAGAYAINNHTQVV--APQALLAGLAAALPD--QRIKFPCVDLELTDD--IPAQGQLLLGELQ
TQPSNGVVAWRAGKRLTRTLAPLAGGP---SKRPPSEKPGVIIIAGGTGGVGAQLARHLATHNQPTLILLGRSALDAQRS------SLL-EQLNDLGAVA
RYCQVDICDPQQVDQLIAELAASSN-GIFGIIQAAGIVDVGSLQAKSAQQLLAVLAPKVSGTWLLARALERYQPAFFINCSSIAAVVAGLGIADYVAANA
FLDAFAASER-QAGRPMTTLNWAAWDGIGLAANPMLVEQLRQRGLPPLHPSQALQAFDQVLYTEQRQVVI-------------LAPVESAEPQ-------
-----------YQATKAAITPPVAIS--------------NPAM----NVTQQIQALVGNALK------------------LPPEQISEDASFLALGLDS
LQAVDLVKQLEQTLGTTLPLTLFFEFQTIRELVAYLS-------------
>tr|A0A0P6YY26|A0A0P6YY26_9CHLR Uncharacterized protein OS=Herpetosiphon geysericola GN=SE18_08255 PE=4 SV=1
---QQLVWQPTVLPASAEQLIEHWILIASPDELAKQLAAMLNTTNQPCVLTNGE-----------------SLPKQLATLGQRYGLPTT--------SDQ
-----------PATAGVLDLLAVSKLILALPEGLWVVTAGAYPIEQQEQIA--PEQALIAGLAAALPD--QHLGIPCVELALNAE--AAAQLQALALELQ
FQPSNGVVAWRGGQRLARALATLPAIT---TSHKPAELPGVIVIVGGAGGVGAQLARHLASNNQPTLILLGRSALDQARK------TLL-AELTALGATA
HYRQVDICLAHEVEQLIAELAATEA-GIFGVIQAAGIADVASLHSKSAEQFAAVLEPKVKGTWLLARALERHQPAFFLNCSSIASVMPGLGIPDYVAANA
FLDAFAASER-QAGRAMTALNWGAWDGIGLAATPMLVEQLRQRGLPPLQPSQALHAFEQVLYADQRQIVI-------------VAPAETQQPQ-------
-----------AISQPL-LKRASAAS--------------LNSN----ELSQHIQALVAKALK------------------LPAEQIATDASFLALGLDS
LQAVDLVKQLEQATGTILPLTLFFEFQTISQLAAHLS-------------
>tr|A8LW93|A8LW93_SALAI Beta-ketoacyl synthase OS=Salinispora arenicola (strain CNS-205) GN=Sare_4951 PE=4 SV=1
----------------------------------------------------------------VILIGDPEVTAPLSAQFTAAGTDSLEVASGWIVDLP
PAALADEPLERATRRAAWTLIRTVQQLIEVQAPQVLTKG-VRAAVDE----ASLAHAPLWGIGRIVAGEHPEVWGGLIDTDGIEPGNGEQLLRVLRT-AA
GT--EDVISLTSGDLTAIRLAPIERSADG--TPLQCSPSGTVLITGGLGALGLEVARWLVDRGARRLLLAGRRGPPRVSDRQIDAVLALEA----LGVTV
GVVALDITDADRVAATLAP-GALGLPPIRGIVHTAGVVKDDLVDKVDLDGLREVLAPKAGGALVLHRLFPPGSLDFFVMFSSCGQFARLSGQTSYAAANS
VLDALAAHRN-ASGHTTISLGWTAWRGLGLSENIATMFEANSRGLEAVSAAEAFRAWAFGDRFQASYQAI------------LRVLP-TP---------P
NLPRVPMLRELTATNEAGTD--H-AGQ--------SFTLDLGSLTQDEAIE-----------------RVTTDVREQVATELEPASIELKRPLVELGVDS
VMAVALRVRLQRRYGLDLPPTILWAKPTVAALSEHVHTN-----------
>tr|A4FKZ4|A4FKZ4_SACEN Iterative type I polyketide synthase OS=Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NC
----------------------------------------------------------------VIIGDDDPVTTGFAELLEEQGILCRRISTP------
---PHDEDPVDQAERATWSLIRATQRLPRTAENVCITRG-VRAGNDR----TALAHRPLWGAARIISGERPDLWGGLIDVESG-RSQERLLKLVLGT-PL
DG--EDIIAVGDDGDYVERMVPVTREPAR--SELECRPDGTYLVTGGLGAIGLQVARWLVGRGARRLVLAGRNGPPRVTDTRIEAVRSLEY----LGATV
RVVAIDIADPGQVADSLTP-SALGLPPIRGVVHAAGVVNDALAENMDTDGLARTMSPKARGAMALHQQFPPGTLDFFVLFSSSGQFARTTGQVTYAAANS
FLDALAAYRR-AAGCHTISVAWMAWLNTGMAASIESMAEARANGIDGFTPEEAFQAWQFVSRFDLPYAVV------------LRSIP-IP---------G
NVPRPAVLSELTASGDTGPD--E-GPS---------IVEGWASLPHDELRK-----------------HINADLIGQVAEELPISEVDVRRPLPESGVDS
VIAVAMRARLQRRYGLALPPTVLWDRPTINALSEHITEL-----------
>tr|U6ZZ87|U6ZZ87_9PSED Uncharacterized protein OS=Pseudomonas sp. CMAA1215 GN=P308_27520 PE=4 SV=1
----------------------------------------------------------------VLLGSDDDAAQRLSLGLRRAGIEHARVRDG------
----DDEALSDAVEANAWRLLQATQQVQRLAPSLCVTFG-VKAMANR----TALAQSPLWGVARIVAGEQPGLWAGLIDIDPA-------TFGLLRG-AH
KS--EDVLAIGTQACQVLRLQEAVAPGPK--GKPQCVPDATYAITGGFGALGLQAAQHLVNQGARRLVLIGRQGPTRLQDLVIDGIRALER----QGVTV
LPLALDIADTAKVAEALSE-SALGLPAIRGVVHAAGVFKGGMIEHLQRASLSQVLRAKVTGTLALERAFPPGSLDFLVLFSSSGQLARPSGQAGYAAANA
FMDGFARYRA-GQDGQTLSIAWMAWEQLGMSSNIDTLRECAANGLGALSIPTALSSWQLAQDCGAPYAAV------------FRVQR-SA---------D
LGQPLPVLSRLLCDAAQE----A-AQV--------TSVDPWRAVPDEQLGQ-----------------WLAQDIQALIAAELAPEDINPQRSLVEKGMDS
LLSVALRIRLKQRYRIDLPPTLIWNHPTVEAIARYVRQA-----------
>tr|Q84HC6|Q84HC6_STRCZ Iterative type I polyketide synthase OS=Streptomyces carzinostaticus subsp. neocarzinostaticus PE=4 SV=1
----------------------------------------------------------------VILVGDPEATVPLAEQLESAGMTCVQVGDS-ETGLR
PDLFSDTAPEEEAERVSWLLVRTVQRVAEIRPAQCVTSD-VRRARDE----RSVAHGPLWGLARIVAGDHPELWGGAVDIGPSADGIGARLVALLDG-AA
GT--EDVISLTGEGAEVARLSRIDRSADG--TPLQCSPSGTVLITGGLGALGLEVARWLVDRGARRLVLVSRRAPNRVTDRRIDGVLALEA----LGVTV
RVLALDITDVDQVSAALAP-EALGLPPVRGVVHAAGVVNNALVDKVDLEGLREVLAPKVRGAMVLHRLFPPGDLDFFVLFSSCGQFARLSGQASYAAANS
FLDTLASHRN-AGEHTTVSLGWTAWRGLGMSSNIDTMFEANSRGLEAVSATEAFGAWSFGDRFQSDYQAI------------LRVVP-TP---------V
HTPRLPVFRDLPVSGETDGP--T-GDQ--------LFTTTLEGLPEQEARE-----------------RITADVREQVAGVLDPSEVEVKRPLVELGVDS
VMTVALRVRLQRRYGLELPPTILWAKPTVAALSEHVCDS-----------
>tr|R4LI09|R4LI09_9ACTN Iterative type I polyketide synthase OS=Actinoplanes sp. N902-109 GN=pks3C PE=4 SV=1
----------------------------------------------------------------IALLGDDTAAA----RLAGTGLPCRRLD------AP
EDLLGTGNPADDAEEAAWTLIRTAQCLSERQAPACLTHG-VRDTTGP----AALAHAPLWGAGRIVAGEHPEIWGGAIDLDDTDTGLAAGLAAVLAG-AA
GQ--EDVIALSADGAAVPRLTRIERPAET--AGLQCRPADTYLITGGLGALGLLVARWLADRGARRILLAGRRAPPRVTERQIDGLLELEA----LGVTV
RTAAVDITDAAAVARALDP-AVHGMPPIRGVVHAAGVVRDAMVDKTDRDQLRDVLNAKVRGAMVLHELFPPGTLDFLVLFSSCGQFARLTGQTTYAAANS
FLDALARHRH-AAGDTTRSIGWTAWRGVGMSESIATMLEANARGLDAVSVAEALRSWAFADRYTSPYQAV------------LRVLP-TA---------S
AGAGVPMLRDLSASRDETAD--A-GPQ--------A--VDWAALEPADLRE-----------------QVGTAVREQVAAELAPADLDVRRPLVELGVDS
VMTVALRVRLQRTFGLDLPPNILWSRPHVAALTDHVADA-----------
>sp|B4XYB8|AZIB_STREG 5-methyl-1-naphthoate synthase OS=Streptomyces sahachiroi GN=aziB PE=1 SV=1
----------------------------------------------------------------ALVVGGAAGGPALVEALTARGVRARAVPDA-----G
DASLPGEAPEQAARRCAQLLVDAVQQVAAV-RRPALTRE-VRAGATE----AALAHAPLWGAGRIVAGERPDLWGGVIDVAEN--AVPQQVASLIGA-LP
HT--EDVLSLDSEGVTAARLRQVARPAER--EPVDCRPDGTYLVTGGLGALGLEAARHLVEQGARRLVLIGRRGPSRVDDAQIAEVVALEA----AGATV
RVLSLDISDAEATARALDP-GALDMPPVRGIVHCAGVVSDALVEKTGAANLDTTMGPKADGAMVLHRLFPAGTLDFFTMFSSCGQLARLTGQVSYASANS
FLDALAALRR-SRGETTTSFAWAQWIGRGMGETTGTILEAESRGLGGITVSEALRSWAYADRFALPYAAV------------MRVMP-DH----------
---TLPVFSHLSVTDAGAQ-----SAD--------AGGVDWATVPAGELPE-----------------LVLKVTHEQVAAELAVDDIAIDQPLLELGVDS
VLTVALRVRLHRCFAVDLPPTILWSNPTVRALAEFLAAE-----------
>tr|E3FE06|E3FE06_STIAD StiE protein OS=Stigmatella aurantiaca (strain DW4/3-1) GN=STAUR_4831 PE=4 SV=1
NWLYSPQWRPVPPHPETPVRQVHCLVFADKGGLSEDLSRHVRGAGKCTLVHRGDEFRRNEDGSYSVPLRNPEAFLRVVDEVSREGLVPSHVVYLWGLDVP
KPDLSVA---QLQDEACGGVLYLTQALLKGSAGTAVSSLWVITRGAQRVAFPGLLSSPLWGLGKAIAYEHPELDCRRVDLTPRR---GEDEAGQLWTEFL
AHDREDQVTFRNGTRHVLRLGRWDWEQAG---RLQFKADATYLVTGGLGGLGLLVARWMVERGARNLVLLGRKRASDVSTDE---VREMRG----RGATI
VLAGVD-SDLDYVMAGISK----RMPPLRGIIHAATEVDDGILVHQTRERFGRVFTAKVSGAWNLHRWLADKELDFFLSLSSSTSLMGASGQSNHLAATA
FLDGLAEYRR-SLGLHGQSSSWGAWAQPGDEAAQALDSRMRKRGVGMMHSQQAFA-VLEQVFGQVPAV-AGV----MPIHWPTFLGLPGDDLPPLFADFW
SDAGP---GRAGSEIRHELVRRVRGSS----------REEARSAVL-TYFRERILEMGTAQLPEP------------------------EQTLHELGLDS
LMGVELKKLLLTELRVEFPLQALLAGKSIVELADSL--------------
>tr|L7UHB2|L7UHB2_MYXSD Polyketide synthase OS=Myxococcus stipitatus (strain DSM 14675 / JCM 12634 / Mx s8) GN=MYSTI_06007 PE=4 SV=1
AWLYAPRWRRVAL---SERDTAHCLVFSDRGGLGAALARSMSGTARCTFVHRGEVFRRHDDGSYEVPIRNPEDFLRLTEALASEGTVPSRVVYLWSLDGP
KPELTVS---QLQDEVCGGLLYLTQALLKAGASHPASSLWLVTRGAQRAGVPGLAGASLWGLGKAIAYEHPELDCRRVDVDPGR---DVESARALWTELR
SRDGEDQVLLHEGARRVLRLARWDWEGAG---RLQFRADATYLVTGGLGGLGLQVARWMVRRGARNLVLLGRKRASDVSTEE---VREMRA----QGAAI
ILAGVD-SDLDFVMAGISK----RMPPLRGIVHAMTEVDDGILLHQTRERLGRVFTAKVAGAWNLHRWLEGTPLDFFHMVSSSTSLMGGSGQASHLSATS
FLDGLAEYRR-SLGLPGQSSSWGAWAQPGDEASEALDARMRKRGVGMVPAAEAFS-VLEQVFGPVPAS-VGV----MPIHWPTFLGLPGDGPPPLFADFG
GDARP-----ARAELRRELLRRVRGGS----------VEEGRGAVL-EWFREQVLELNASQWPEP------------------------EQTLHELGLDS
LMGVELKKLLHAQLRVEFPLQELLGGKSIGELSGSL--------------
>tr|A0A0F7E6Z7|A0A0F7E6Z7_MYXFU Uncharacterized protein OS=Myxococcus fulvus 124B02 GN=MFUL124B02_24050 PE=4 SV=1
TWVYAPAWRPVPP---TTTPPGHCLVFVDQGGLGEALSRRVGEAGRCTFVHRGEVFRQREDGGYEVPTRNPESFLRLMEALSAAGHVPSHVVYLWSLDVP
EPELTVA---RLQDEACGGLLYLAQALLTAGASHPASSLWMATRGAQRAGLPGLLAAPLWGLGKAIAYEHPELDCRRVDLDPRR---DPDGAQALWMELS
SRDDEDQVLLREGRRHVLRLARWDWEGEG---RLQFKADATYLVTGGLGGLGLQVARWMVERGARNLVLLGRKRASDVSAEE---VKEMRA----RGAAI
ILAGVD-SDLDFVMAGISK----RMPPLRGIIHAATEVDDGILVHQTRERLGRVFAAKVSGAWNLHRWLSGTPLDFFFSLSSSTSLMGASGQGNHLAATA
FLDGLAEYRR-SQGLPGQSSSWGAWTQPGDEAQAALDARMRKRGVGLVPTRQAFA-ILEQVFGPMPAV-VGV----MPIHWPTFLGLPGDGPPPLFADFG
AEAGA---GRAGAELRRELLRRVRQGS----------AEDGRSAVL-EWFRARVLELGVTQLPEP------------------------EQSLHELGLDS
LMGVELKKLLHAELRVEFPLQELLGGKSIGELSGSL--------------
>tr|F1TIW2|F1TIW2_9FIRM Beta-ketoacyl synthase (Fragment) OS=[Clostridium] papyrosolvens DSM 2782 GN=Cpap_0012 PE=4 SV=1
--------------VTEKQLQGSYIIFDGTDGLSQHISRQLSSEDNSITVYLGKKYYIAN-NYIEIDASTKEHYTHLFDYLKTKNINISGIIYIPGSTVK
NDNLSINNVEKDFYDNLSSLFNIIKSLIKNKQFITLTFNGDNTYNEKLNIYPHMQSLQV--LTKVFSNEEKGVSFLNLDYEASADL--EFIGGTVADELL
TADRNMDVCYRKGKRFVKDFVKINVEPSN---SNCIKSMGTYIITGGGSNIGVKIAEFVVKQAPVRIAFIGRSQEPSEK--------LKEAIAEKAGSKT
MYFSCDVADLTELEKTVKKIEDNFG-EVNGIFHCAGIKDDSLLQNKELPAFKKVLSPKVKGLLNFERIFSNKPVEFVLLLSSVSSYFCNQGQADYSVANC
FYNSYAKSAFKKSAKRVISLCLPFVNGGGMKSTDIVLKRMENYGIYSVELEEVIEALKVSLSHKDINTFCKHTGSAL----------------------K
------IIPGVYSNKIKCYN-K-NGKSRV---------------PCNNIDKNRCDNLLHNAENE---DNVKKYIRTLILRLLDPQEMDDSVNFGDYGMDS
MLIKEATVLFEREFNTQIESSIFLEYPNVAELAGYLSE------------
>tr|F1TBP3|F1TBP3_9FIRM 6-deoxyerythronolide-B synthase OS=[Clostridium] papyrosolvens DSM 2782 GN=Cpap_2600 PE=4 SV=1
--------------ENTPLNSFVWVVFCDKQELYANIRESLKTRNKVILVFADDKYYKKD-SCNTINSYLEEDYKVLFKDIIKDFGRVDTVINLWAY---
----TNTEFQETTYASVYGLLGIALGLNANKGLISITNHSEDIDKISVGGYP----VHM--LSRLISAEIKNIAARSIDFNGLESK--EVVEDVIFKYSL
TKNGFSELAYRHGKAYIRMLKKNTLQKIL---NSVWKDGGVYVITGGATGIGAEIGLHIAKKVKAAVILIGRTKLPEKSEFREAVIEKIENIIQEAGAKV
EYYNGDISDELKTIEILDNISKRFG-HITGILHCAGAKRDGIITAKSFKDFQYAIAAKVSGISNIKKAIEGKSVDFVVAFSSIAALYGTPGQSDYSSANA
LMDAFINDWSGNTETFVTSINWTLWDGAGMDIPLLAKRKMENDGLLPLEISDGITALERLLQDRKASNYIKLSESD-----------------------K
------FIKDLFESKMRNPMSK-NGLFLSGT------------QSSKNMSVHKTTN-----TFE---KETKEFLLKMLSELLEATDIDTSRGLDEYGMDS
LAIKEALAALEKQYDTVLEPSLFEENPTIDKLVVYLAD------------
>tr|W7W5T1|W7W5T1_9ACTN Modular polyketide synthase OS=Micromonospora sp. M42 GN=MCBG_06026 PE=4 SV=1
----------------------------------------------------GMAAVQLRHLGAEVYATSPA----KWDALRALGLDEEHLASSRTLD--
----FETRFTDA--TGGRGVDVVLDSLAR-------EFVDASLRLLPRGGRTDIRDAAR------VAVDHPGVAYTAFDLTLQ----EPDEVQRMLVVLL
GLFEQAPEAFRSQARHVGKV-VLTMPRAW---N----PDGTVLLTGGTGTLGRLVARRLVETHGRRLLLVSRRGERAPG------ATEALDELRALGAEA
TVVAADVSDRDNLAGVLAAV--PERHPLTAVVHLAGVLDDGVVTALTPQRVDTVFAPKLDAAWHLHELTRHLDLAGFVLFSSGAGVFGVPGQANYAAANA
FLDALALARR-AQGLPGRSFAWGLWEQSEMTAKLTDPRITARDGQLAIPSELGMALFDAGLRLAEPVLVTRIDVAALGERAER---------PPALRGLL
------------R---RE-RPTAR---------------AATPAGGGRTLADELA-------ALDGPERHTLVVDLVREQVLGHGAVAPGRAFSQIGFDS
LTAVELRNRLTTATGLRLPATLIFDYPDPNELATYLVSE-----------
>tr|J1RVD6|J1RVD6_9ACTN Beta-ketoacyl synthase OS=Streptomyces auratus AGR0001 GN=SU9_33643 PE=4 SV=1
----------------------------------------------------GMAAVQLRHLGAEVFATSSG----KWGTLRGLGLDEAHIASSRDLD--
----FERSFLEA--TDGRGVDLVLDSLAR-------EFVDASLRLLPRGGRTDVREPER------VAAEHEGVRYQAFDLMEA----GADRIGEMFAQVR
ELFERAPEAFRSQARHVGKV-VLTMPVSL---D----VEGTVLVTGGTGGLGALVARHLVAEHGRHLLLASRRGPKAPG------VDELRDELRALGAEV
EVAACDIADREALSGLLDSV--PKHHPLTAVVHTAGVLDDTVVTSLTPQRLRAVLRPKADATVHLHELTRDEDLAAFLVFSSTAGVFGAPGQANYAAANA
FCDTFAAERR-AAGLPATSLAWGPWSQTGMTSGLADLHRMARAGLPALPADRGLALYDAALGRPEAALLMLVDPRALGSGGPV---------PPLLSGLL
------------P---TAARRTAG---------------PAAPAGSAETLTRTLA-------TLTRDEAHHALLDVVCTQVLGHAEVGDQQSFKDLGFDS
LTAVELRNRLGAATGALLPATLVFDYPTPLALADHLCAE-----------
>tr|X8FFI3|X8FFI3_MYCUL Zinc-binding dehydrogenase family protein OS=Mycobacterium ulcerans str. Harvey GN=I551_2654 PE=4 SV=1
----------------------------------------------------GMAAVALKYWGAEIFVTSRG----KWDTLRAMGFDDEHIGDSRSLE--
----FEEKFRKT--SGGPGVDVVLNSLAG-------EFTDASLRLLVSGERTDLRDPQA------VADEYPGVSYRAFDLMEA----GPDAIARMLSEVV
GLLQSAQQAYRSQARHIGKV-VLTLPQGP---A----AGGTVLITGGTGMAGAAVARHLVQRYGGHVVLVNRAGTQAPG------IADLVAELQQGGAQV
SVTACDVADRDAVAALLAQL--PDRYPLKGIFHAAGVLDDAVLASLTPDRVEPVLRAKAAGAWNLHELTHGMDLVAFVMFSSLAGIAGAPGQGNYAAANA
FLDGLAAYRR-GQDLPAVSIAWGLWEQSTMTQHLRDLARMRRAGLDPLSTEHALHLLDAALLGERPGVVAQLNVAALSAN-EV---------PPIWRDLV
------------T---RSVRRVVN-------------------DASMTALISRLH-------TLSPEQRSREPVDMICTNVLGNADIDANKPFQDLGFDS
LTAVELRNRLKSSTGLTLSPTLIFGYPTPAALAEHLSTH-----------
>tr|X8AKR6|X8AKR6_MYCAV Zinc-binding dehydrogenase family protein OS=Mycobacterium avium subsp. avium 2285 (S) GN=I548_1247 PE=4 SV=1
----------------------------------------------------GMAAVQLRHWGAEVFVTSRG----KWDTLRAMGFDDDHIGDSRTLE--
----FEEKFRAV--AGDRGFDVVLNSLAG-------DFTDASLRLLAPGGRTDVRDPRV------VAEQYGGAQYRAFDLLEA----GPDRTAAMLAEIV
GLLTCAAAAYRSQARHVGKV-ALTVPSGP---G----EGGSVVITGGTGMAGSALARHLVDRYGAHVVLVSRAGAEAPG------VAELVDGLRRAGADV
SVEACDVADPDAVGAMLSRI--PAHYPLRGVVHAAGILDDGLISSLTPDRVDAVLRAKVDGAWNLHQLTRDLDLSAFVVFSSMAGIVGTPGQANYAAANS
FLDGLAAYRR-AHGLAGLSLAWGLWEQSAMTAHLRDKARMSRIGLAPLPTGQALAAFDAAMLVDRPVLVAAVDRAALSDN-AL---------PPLLRELA
------------A---GPARRVVT---------------GA---ASSTGLSARLN-------GLSPEARQRELIDLVRGNVLGVPDINVGRAFQELGFDS
LTAVELRNRLKNATGLTLSPTLIFDYPTPTVLAGHLDTQ-----------
>tr|Q93C91|Q93C91_9ACTN Polyketide synthase 1 (Fragment) OS=Actinomadura verrucosospora PE=4 SV=1
----------------------------------------------------GMAAVQLQHAGAEVYATSPA----KWPVLRALGLDDEHLASSRDLA--
----FADEFLEA--TGGRGVDVVLNSLAH-------AFVDASLRLLPEGGHTDIRDPRR------VAADHPGVDYRAFDVYGA----GPELLQEMTRAVM
DLFADARKAFRSHGRHVGKL-VLDVGGGF---G-----GGTVLVTGGTGGVGSLVARHLAAEHGRSLVLASRRGTAAGG------VRELVADLEAAGAAV
TVVACDVADRAAVADLIADM--PARYPLTAVVHAAGAVADGTVESLTAEDLDHALRAKVGGAINLHELTKGHALSAFILFSALAGALGAGGQANYAAANT
FLDGLAARRR-ASGLACTSLSWGWWERGGMTAGLARLARLRRLGAVEMPASEALALFDAACDHGGPLLIARVDLGALRGAAEL---------PPVLRDLV
------------H---GGRPSRGG-------------------QEGPRGLTARLA-------ALADGEAEAALLDWVREQVLGHTSVDADRAFTHLGFDS
LTSVELCNRVASSTGLRLPSTLVFSYPTPRELGRHILGL-----------
>tr|V7N4Q7|V7N4Q7_MYCAV Inactive phenolphthiocerol synthesis polyketide synthase type I Pks1 OS=Mycobacterium avium subsp. hominissuis 10-5606 GN=N602_
----------------------------------------------------GMAAVQLRHLGLEVFATSRG----KWDTLRDMGFDDDHLGDSRGLD--
----FEDKFRAV--TGGAGMDIVLDSLSG-------DSVDASLRLVAPGGITDIRDPEV------VAAEHPGVRYRAFDLFEA----GPDRIARLLDELA
AMFGRAPAALRSQARHVGKV-VMTMPDAW---T-----AGTVLITGATGMAGSAVARHVVTRHGRNLVLVSRRGLDAPD------AAELVAELTAAGAHA
EVVACDAADREALAKVIADI--PMQHPLTGVIHAAGVLDDAVVTSLTPQRIDTVLRAKVDAAWNLHELTRDLDVGAFVMFSSIAGLAGASGQGNYAAGNS
FLDGLAAHRR-AHGLPAISLGWGLWDQSAMTGGLADLARFGRDGIVAMSSQEALELMDTALIVDEPFLLAHIDLAALRVKFTL---------PPMFVDLI
------------N---APTRRQVS---------------L---AKSKSALLQRLE-------GLPEDEQQAVLLDLVRSNVLGSSAIHPDRAFQELGFDS
LTAVEMRNRLKAATGLALSPTLIFDYPNSAALAGYMYRE-----------
>tr|I0RQ19|I0RQ19_MYCXE Polyketide synthase OS=Mycobacterium xenopi RIVM700367 GN=MXEN_11615 PE=4 SV=1
----------------------------------------------------GMAAVQLRYWGLEVFATSRG----KWDTLRAMGFDESHIGDSRTLE--
----FEDKFRAV--TGGRGMDVVLDSLAG-------EFVDASLRLVAPGGITDIRDPNA------VAQQHPGVRYRAFDLFEA----GADGIQRILTDLA
AMFARAPAALRSQARHVGKV-VLTMPDVW---A-----AGTVLITGGTGMAGSAVARHVVARHGRHVVLLSRRGAEAPG------VGELVGELGGSGATV
RVVACDAADREALAKVISDI--PVQWPLSAVIHAAGVLDDAVVTSLTPQRVDAVLRAKVDAAWNLHELTRDLGVSAFVMFSSMAGLVGSSGQANYAAANA
FLDALAAHRR-ANGLPAMSLGWGLWEQSAMTGQLVDFARFARDGVVAMSSEEALQLFDTAMVVDQPFVLARIDLAALKAKFTL---------PPMFVDLI
------------N---APARRQVS---------------L---AKSKSALLQRLE-------GLPEDEQHAILLDLVRSNVLGNTAIDPDKAFQELGFDS
LTAVEMRNRLKAATGLALSPTLIFDYPNSAALAGYFRQE-----------
>tr|V7KEA2|V7KEA2_MYCAV Uncharacterized protein (Fragment) OS=Mycobacterium avium subsp. silvaticum ATCC 49884 GN=P863_13240 PE=4 SV=1
----------------------------------------------------GMAAVQLRHYGAEVFATSRG----KWDTLRAMGFDDDHIGDSRSPD--
----FEQKFLAA--TGGAGVDVVLNSLAG-------EFTDASLRLLAPGGRTDVRDPDV------VAQRYRGARYRAFDLMEA----CPDRTAAMLAEIV
GLLRCASAAYRSQARHIGKV-VLTVPSGP---G----EQSTVLITGGTGMAGSALARHLVDRYRGHVALVSRTGAQAAG------AAELVDELKRAGASA
SVLACDVADRDAVATMLAGL--PAGYPLRGIVHAAGILDDGLLSSLTPDRVDAVLRAKVDGAWNLHELTKDLDLSAFVVFSSMAGIVGAPGQGNYAAANS
FLDALAIHRH-AHGLPALSVAWGMWEESAMTAHLRDKARMSRAGLSALSTRQALDLLDDALLGEQPLVVTRLDRAALAQH-AL---------PPLLSELA
------------G---RPARRMLT---------------DM---VSLTGLRARLA-------GMNPEQRQAELVELVCGNVLGHSDVDPGDAFSDLGFDS
LTAVELRNRLKIATGLTLSPTLIFDHPTPAALAEHLGGQ-----------
>tr|D6FKI1|D6FKI1_MYCTX Polyketide synthase PKS1 OS=Mycobacterium tuberculosis CPHL_A GN=TBNG_03607 PE=4 SV=1
----------------------------------------------------GMAAVQLRQWGVEVFVTSRG----KWDTLRAMGFDDDHIGDSRTCE--
----FEEKFLAV--TEGRGVDVVLDSLAG-------EFVDASLRLLVRGGRTDIRDAQE------IAANYPGVQYRAFDLSEA----GPARMQEMLAEVR
ELFDCAPAAFRSQARHIGKV-VLTMPSAL---A----DDGTVVITGATGAVGGVLARHLVGAYGRHLVLASRRGDRAEG------AAELAADLTEAGAKV
QVVACDVADRAAVAGLFAQL--SREYPVRGVIHAAGVLDDAVITSLTPDRIDTVLRAKVDAAWNLHQATSDLDLSMFALCSSIAATVGSPGQGNYSAANA
FLDGLAAHRQ-AAGLAGISLAWGLWEQGGMTAHLRDLARMSRSGLAPMSPAEAVELFDAALAIDHPLAVTLLDRAALDARAAL---------PALFSGLA
------------R---RPRRRQIT------------------GDSSKSALAQRLH-------GLAADEQLELLVGLVCLQVLGRPDVDPDTEFGDLGFDS
LTAVELRNRLKTATGLTLPPTVIFDHPTPTAVAEYVAQQ-----------
>tr|D5P327|D5P327_9MYCO Phosphopantetheine attachment domain protein (Fragment) OS=Mycobacterium parascrofulaceum ATCC BAA-614 GN=pks5 PE=4 SV=1
----------------------------------------------------GMAAVQLRHWGAEVFATSRG----KWDTLRAMGFDDDHIGDSRTLE--
----FERKFAAA--TGGAGVDVVLNSLAG-------EFTDASLRLLAPGGRTDVRDPDV------VAERYGGAQYRAFDLLEA----GADRTAAMLAEIQ
GLLRCAPAAYRSQARHIGKV-VLTLPGGP---G----GGGSVVITGGTGMAGSALARHLVERYGAYVVLASRAGAAAAG------VAELVDRLQEAGARV
SVVSCDVADRDAVAAMLGGI--PDEYPLRGVVHAAGVLDDGLVLSLTPDRVDAVLRAKVDGAWHLHELTRHLDLSAFVVFSSMAGIVGTPGQANYAAANS
FLDGLVAHRR-AHGLAGLSLAWGLWEQSAMTAHLRDKARMSRLGIAPLSTEQALESFDSAMLVDAPVLMARLDRVALSDN-AL---------PPLLSELA
------------A---RTTRRVVA---------------AT---ALTTGLTARLH-------GLTPEARRRELVDLVRGNVLGLPDIDAGRAFQELGFDS
LTAVELRNRLKTATGLTLSPTLIFDYPSPAALAEHLDGQ-----------
>tr|X8FF49|X8FF49_MYCUL Zinc-binding dehydrogenase family protein OS=Mycobacterium ulcerans str. Harvey GN=I551_2648 PE=4 SV=1
----------------------------------------------------GMAAVQLQLWGLEVFATSPG----KWDTLRAMGFDDDHIANSRTLE--
----FEEKFRAG--TGGAGVDAVLNSLAG-------EFVDASLRLLVPGGRTDLRDPQT------MAEQHRGVGYRAFDLIEA----GPDLIAGMLAELS
RLLCLARQAYRSQARHIGKV-VLTLPDET---G----AGGTVIITGGTGMAGTALARHVVSRHRANVILVSRSGAQAEG------TSELLGQLQDAGAEA
AVAACDVSDRDAVAELLAQV--PARYPLRGVIHAAGVLDDGLIASLTPQRVDTVLRAKIDGAWNLHELTRGLNLSAFVLFSSMAGIIGTAGQGNYAAANS
FLDGLAVHRR-ALGLPGVSVAWGLWEQSAMTRHLRDKARMSRVGLATLSTEHALELFDAAVVADPAVVVTRLDANALKSN-AL---------PPLLGELA
------------A---RPKRRLIA---------------DA-GDAAATGLVARLH-------GLSAEQRQRELVDVVCSNVLGRSDFNAHRAFQELGFDS
LTAVELRNRLKTATGLTLSPTLIFDYPSPAALAEHLGIR-----------
>tr|V7MNP9|V7MNP9_MYCAV Polyketide synthase (Fragment) OS=Mycobacterium avium subsp. hominissuis 10-5606 GN=N602_25725 PE=4 SV=1
----------------------------------------------------GMAAVQLRHYGAEVFATSRG----KWDTLRAMGFDDDHIGDSRSPD--
----FEQKFLAA--TGGAGVDVVLNSLAG-------EFTDASLRLLAPGGRTDVRDPDV------VAQRYREARYRAFDLMEA----GPDRTAAMLAEIV
GLLRCASTAYRSQARHIGKV-VLTVPSGP---G----EQSTVLITGGTGMAGSALARHLVDRYRGHVVLVSRTGAQAAG------AAELVDELQRAGASA
SVLACDVADRDAVATMLAGL--PSGYPLRGIVHAAGILDDGLLSSLTPDRVDAVLRAKVDGAWNLHELTKDLDLSAFVVFSSMAGIVGTPGQANYAAANS
FLDGLVAHRR-ADGLAGLSLAWGLWEQSAMTAHLRDKARMSRIGLAPLSTEQALAAFDAAMLVETPVLVARLDRAALSEN-AL---------PPLLRELA
------------A---GPTRRVIA---------------DV---ASMSGLAARLH-------GLSPEARRRELVDLVCGNVLGVPDINAGRAFQDLGFDS
LTAVELRNRLKNATGLTLSPTLIFDYPTPVVLAEHLDSR-----------
>tr|A0A0E9A5I1|A0A0E9A5I1_MYCTX Putative polyketide synthase pks12 OS=Mycobacterium tuberculosis GN=pks12_4 PE=4 SV=1
----------------------------------------------------GMAAVQLRHLGLEVFATSKG----KWDTLRAMGFDDDHISDSRSLE--
----FEDKFRAA--TGGRGFDVVLDSLAG-------EFVDASLRLVAPGGVTDIRDPGV------IAQQYPGVRYRAFDLFEA----GPDRIAQILAELA
TLFGCAPAALRSQARHTGKV-VMLMPGSW---A-----AGTVLITGGTGMAGSAVARHVVARHGRNLVLVSRRGPDAPG------AAELVAELAAAGAQV
QVVACDAADRAALAKVIADI--PVQHPLSGVIHTAGALDDAVVMSLTPDRVDVVLRSKVDAAWHLHELTRDLDVSAFVMFSSMAGLVGSSGQANYAAANS
FLDALAAHRR-AHGLPAISLGWGLWDQSAMTGGLVDFKRFARDGIVAMSSADALQLFDTAMIVDEPFMLAHIDFAALKVKFTL---------PPMFVDLI
------------N---APTRRQVS---------------L---AKSKSALLQRLE-------GLPEDEQHAVLLDLVRSHVLGSAAIDPDRAFQELGFDS
LTAVEMRNRLKSATGLALSPTLIFDYPNSAALAGYMRRE-----------
>tr|G2NTV8|G2NTV8_STRVO Beta-ketoacyl synthase OS=Streptomyces violaceusniger Tu 4113 GN=Strvi_3959 PE=4 SV=1
---------------------------------------------------VSADSAPPTASWALVGPRHWPAYPDL-AALRAALDGAPDVVVLSGAPDA
TPPDE--TPT-RVRAVVHDVLGTTWLTDERFSGARLVIATRGAVAGAGDAPADLATAPVWGLVRAAQAEHPERILL-LDLDDD--TA-SRDVLRTALPAA
VAGAESEVAVRAGTAHVPRLVKVRPDEDQDTPPRALDPDGTALITGGTGALGRLVARHLTAHGVRHLLLVSRRGGITGD------IDAFADELTALGADV
RIAACDAADPEALAALLATLPAAH--PLTAVIHAAGVLDDGVVTAMTPEQLDTVLAPKLDAAWHLHRLTRNMDAA-FVMFSSAASIMGNGGQANYAAANM
FLNALAEHRR-AEGRTAHTLAWGLLASAGGMTGHLELARMARSGIAPVSGEQALTLLDTALTTDHPTL------------------------VPARFDLA
------ALRTRAAA---GPLPPV----------LRRLVHVPTRAARTSSLSGRLAGLPT----EEQDRLIGELVRDQVATVLAHPAIELGRAFQDLGFDS
LTALDLRNRLNAATGTRIPATVIFDYPTPDALVRFLRER-----------
>tr|A0A0D0X475|A0A0D0X475_9ACTN Acyl transferase OS=Micromonospora carbonacea GN=TK50_11425 PE=4 SV=1
-----------------------------------------------------------------------EPDVDR-AALAAAL-GLAGVVSLWA----
-PPTT--DAT-L--PGLAATLALTQALGDAGHDAPLWLVTRGAVAAAYDRLADPAQAATWGLGRVVSVEAPHRWGGLVDLPTR--PD-ARAAGRLAAILT
GTTGEDQLAVRGPGVFARRLVRAALG--DRPPARRYTPTGTALITGGTGGLGARAARWLAAAGAEHVVLVSRRGPAAPG------AADLEAELTALGTRV
TVAACDITDRAALADLLRRVEADGP-PVRTVVHTAGVAQTTPLAEVTAAELAEVTGGKTTGATHLHDLLADRDDA-FVVYSSIAATWGSAGQAGYAAGNA
YLDALVQQRR-ADGHAGTALAWGPWADGGMH-GADS---LRRRGVPAMDPAVAMGALAQALDHDDVTL------------------------TVADVDWT
------RFAPAYAS---ARRRPL----------LEGVPGGAPT--DAATLRRRLAGLTP----ARREETLADLIRDHAADVLGHDGIGATTAFRDLGFDS
LTAVELRNRLAAATGQALPTTLVFDHPSPIVLARFLLGG-----------
>tr|D9T6W7|D9T6W7_MICAI Acyl transferase OS=Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442) GN=Micau_2467
-----------------------------------------------------------------------EPDADR-AALAAAL-APAGVVSLGE----
-PRTG--GTV-L--PGLTATLALAQALGDAGGATPLWLVTRGAVAASYDRLVDPAQAAIWGLGRVVGVEAPHRWGGLVDLPSD--PD-DRAVARLAAILT
GSTGEDQLAVRGPGVFARRLVRAALG--DRTPARRFTPTGTAVVTGGTGGLGARAARWLAAAGAEHVVLVSRRGPDAPG------AAALEAELTALGTRV
TVAACDIADRAAVADLLDRVEAAGP-PVRTVVHTAGVAQATPLAEVTPAELAEVTAGKTAGATHLADLLADREDA-FVVYSSIAATWGSGGQAGYAAGNA
YLDALVQRRR-ADGRSGTAIAWGPWSDGGMH-AADA---LRRRGLPAMDPAVATAALQQALDHDDVTV------------------------TVADVDWA
------RFAPAYAS---ARRRPL----------LEGVPGGAAA--DAATLRRRLAALAP----ARREETVAEMVRELAADVLGHDGVGATTAFRDLGFDS
LTAVELRNRLVAATGQALPTTLVFDHPTPAVLARFLLTG-----------
>tr|B4VB11|B4VB11_9ACTN Polyketide synthase type I OS=Streptomyces sp. Mg1 GN=SSAG_04921 PE=4 SV=1
---------------------------------------------------AGT--APAGVTRALVGTAVPAPYADL-ADLAAAG--VPDLVFVGTQDT-
-PALP----E-AVHGRAAEGLALSWLAEERFASSRLVFVLPGAMPGPAGAVRDLAGAALWGLVRSAATEHPGRFAL-VDLDVD--GA---VLPEGALLAA
LASGETELLVRDGSLLVPRLARAAVV---ADAGVEWDAEGTVLITGASGSLGGLFARHLTEHGVRRLLLVSRRGEAP----------ELSAELAGLGAEV
SWAACDVADRDALGAVLAAVSVEH--PLTAVVHTAGVLDDGVVGSLTAERLSAVLRPKVDAAWNLHELTQDLDSA-FVLFSSAAGVFGGAGQANYAAGNT
FLDALAAHRR-AQGLTATSLAWGLWAEVGGMGGALDVSRLGRGGVNAITAAEGVALFDAATSAEQALL------------------------VPVKLDLA
------ALRAQAGS---GMLPPL----------LSGLVAGAAA---ASGPAARLVGLAD----AEQLAFVLELVRTQVAAVLGYAGVEADRSFRELGFDS
LTAVELRNLIGAATGLRLPATLVFDYPTSEVLAGHLRTE-----------
>tr|F8TTM8|F8TTM8_9BACT Polyketide synthase OS=uncultured Acidobacteria bacterium C5 PE=4 SV=1
---------------------------------------------------YGMTATDVRPHHPLMAPRRWEPAGQA-LILANATVSLACTLVSGERTFQ
IDPDR--SDS-RTHRLCESTLYLALTSASLAEPPRLAIVSRGAVS--GETLPGLAGSPLWGMGKSIALEHPELHCLCIDLPAD--GGLDE--ARSLRDEI
RRSTDDQVAYRGDKRCAARIIRDAGP--APEAEFECRPDATYLITGGLGDLGLHAAEWLIVHGARHVMLVSRHGARPEV------EGRIS-KLGSGGAQV
SVRQADVSDKQQVAALFGEIAASWP-PLRGIVHAAGVFDDGTLLELTAERFAAVLAPKIAGAWYLHEQSRELPDV-FVLYSSAASLFGSAGQASYVSANA
FLDALAAART-AEHLPAVSINWGGWSAIGFAARSGT-RVLRGKGIGSLTPAQGAAALDRALTSGHGQL------------------------GIVAVDWQ
------KFFEARVS---A--SPM----------FAAFA-------TRPRLLDALQGKSL----AEVHAWLLQYVASQVAAVLGLASVSTTRNFFQMGMDS
LTSVELRNRLRDGLGQSLPATVAFDHPSVPEMADFLAKP-----------
>tr|A0A0A8EQG0|A0A0A8EQG0_9ACTN Beta-ketoacyl synthase OS=Streptomyces sp. 769 GN=GZL_03710 PE=4 SV=1
------------------------------------------------------------------------TDVDR-EALRAALPSLSGVLSLPADEA-
-HPLH--PAL-S--VGVAGTVALVQALGDAGIDAPLWCVTRGAVSGGSDQVSNPAQAQVWGLGRVAALEHPERWGGLVDLPEA--LD-DRAVTRLVGVLA
GAGDEDQLAVRSAGVFVRRLQPAPVA--ER-GLRKWRPSGTVLVTGGTEPLGARVALWLAQQGAEHLLLTS---PDPRD------TADLEAELAELGAKV
TVAVCDVTDRDAVARLLASVPAEH--PLTAVAHSSPAAEMSALAETELGDFAQVLSSRVSGAAHLDELLDYDSDV-VVYFSSVAGVWGSGRQSAYAAGNA
FLDALAERRR-ATGARALSVAWSPWQGSETAADADG---LRKRGVRAMAPDLALTVLQQVLDHNEPFV------------------------AVADVDWD
------RFLPGFTA---LRPSPL----------FAELPAAEQG--QASELVRSLSGLAE----PEQQRIVLDLVRDHLAAVLDHASVAVERAFRELGFDS
LTAVDLRNRLNTATGLKLPATLVFDYPTPMALAEFLRAE-----------
>tr|A0A0H4WVP1|A0A0H4WVP1_9DELT Malonyl CoA-acyl carrier protein transacylase OS=Myxococcus sp. (contaminant ex DSM 436) GN=A176_002590 PE=4 SV=1
EWLYARQWDALALEGHQGSASGPCLVLSDRAGVGDALARTLAREGPCVVAFQGTGLRQVDARTFEV-PTEPE---ALAEALRSLPVDLSDVILLWGVDSP
VETLDAEGLGQAARVGGGAALGLLQFLLNYAGAVWL--VSRGAQPVTPGATPGLAQSLLWGMARPLAIEASELDCRCVDLDPQ----GAAQAELLARELR
ARTADNQVAFRDGR-YVARVESRKVAAAPSVRSDALRADRTYLVAGGLGRLGLLTAELLASRGARSLVLTGRGPGS---AHAADRIERL----RQQGVRV
DYHQVDIADTESVAALLREVA-RDMAPLGGVFHSAGVLDDGVLRQQRWERFDTVLRPKMRGAWNLHRLTADLPLDHFVMFSSVASLVGSAGQSNHCAANA
FEDALAHHRR-ARGLPGLSINWGIWAG---DAGAQVSEEARTPGFGVLPKEQGLRALELLLAS--SLPQVGVA----------------------AIDWA
------VFGAGRPSPYAELRSKVASTKP----------------AERAAFLETLRS--------APIPRRRQLVMDYVRDQVSSASIDPARGFHELGIDS
LAALQLKNRL----------------------------------------
>tr|Q091C3|Q091C3_STIAD Oxidoreductase, short chain dehydrogenase/reductase family OS=Stigmatella aurantiaca (strain DW4/3-1) GN=STIAU_0878 PE=4 SV=1
ELLYERRWEPLALEGAGEGDNRPCLILADRAGFGRQLAEELTRGGTCFLAFRGQAFRRLDETSVEV-PGEPA---ALAEALRTLPASVSDAILLWGLDGP
AEGMDVESLGQATLLGGGGALGLLQYLMGYSDAVWL--ITRGAQPVKPGQPPGMAQSVIWGMARPVAIESSELDCRCVDLDPR----GEAQVGLLAQEIR
RRSADNQVAYRQGR-YVARVEARKLATPLVERVQRFRPDRSYLVAGGLGRLGLLTAELLANRGARNIVLTGRDSVS---PQAAERLERL----REQGVRV
EYRQADIADLGQLSALLREVG-REMAPLGGVFHSAGVLDDGVLRQQSWSRFETVLRPKARGSWNLHVLTADMPLEHFVLFSSVASLVGSAGQANHCAATA
FQDALAHHRR-ALGLPGLSINWGVWAG---DAGARVNEQARTPGFGVIAKQQGLQALEMLLAA--QVAQAGVA----------------------VIDWA
------AFGAGRPSPYADLREKAGG-RT----------------AGRETFLAKLTS--------APIAHRRKMLMDYLREQVSRESIDPAQGFSEMGIDS
LAALQLKNRL----------------------------------------
>tr|L7UIA0|L7UIA0_MYXSD Non-ribosomal peptide synthetase OS=Myxococcus stipitatus (strain DSM 14675 / JCM 12634 / Mx s8) GN=MYSTI_06014 PE=4 SV=1
GQLYVRRWEPLALDVPARAVSGPCLILADDAGLGHKLARALERDGTCLLAFRGQTLRTLDDKSFEL-PEDPE---ALADALRTLPASLSDVILLWGLDGA
SEDLEGERLDADARRGCGSGLGLLRYLIDYSEAVWL--ITRGAQAVASGQPSGLAQSLLWGMARPLAIESSELDVRCVDLDPR----GEAQVEALAREVR
GRAADNQVAFREGR-FVARAESREVVAESSRD-GPVRSDRTYLVVGGLGRLGLLTAELLAHRGARSLVLTGRGSVG---AEAEGRLERL----RARGVRV
EYRQVDLADEGELSGLLQFIA-DDLAPLAGVFHSAGVLEDGVLRQQTWARFERVLRPKVRGAWNLHRLTSGLALEHFVLFSSVASLVGSAGQSNHCAATA
FEDALAHHRR-ALGLPGLSINWGVWAG---EAGARVDEQSHTPGWGLLSVPQGLRALEALLTS--PVAQVGVA----------------------EIDWA
------VFGGGRTAPYAELREAARG-QP----------------EGRARFLETLSE--------SPVPARRKLLMNYLREQVSGASIDPAQGFNEMGIDS
LAALQLKNRL----------------------------------------
>tr|A0A0F7BML9|A0A0F7BML9_MYXFU Peptide synthetase OS=Myxococcus fulvus 124B02 GN=MFUL124B02_24085 PE=4 SV=1
GWLYERRWEPLALEAAGTKERGPCLILADERGLGPLLARALERDGTCFLAFRGRTFRALDDTRFEL-PEDPE---ALAEALKTLPASLSDVILLWGLDGA
AEDLDLARLDADTVRGCGSGLGLLRYLIEYSQAVWL--VTRGAQAVATGQPPGIAQSLLWGLARPVAIESSELDVRCVDLDPR----SGAQVELLTRELH
ARAADNQVAFRGDR-RVARVSAREVLTASSRWADAVREDRTYLVVGGLGRLGLLTAELLANRGARSLVLTGRGVVG---PEAAERLERL----RTLGARV
EYRQVDVADEDALAALLREIS-GELAPLGGVFHSAGVLDDGVLRQQRWARFESVLRPKVRGAWNLHRLTSKLALDHFVLFSSVASLVGSAGQSNHCAATA
FEDALAHHRR-ALGLPGLSINWGVWAG---DAGARVDARSHTPGWGNLPVREGLAALEALLTS--PVAQVGVA----------------------EIDWA
------VFGGGRSSPYAELRDAARG-RT----------------VERARFLEKLSR--------SPVMHRRKLLLEYLREQVSGASVDPSQGFSEMGIDS
LAALQLKNRL----------------------------------------
>tr|Q6DNE0|Q6DNE0_9CYAN CurM OS=Lyngbya majuscula GN=curM PE=4 SV=1
-WFYKVQWISQAIKPQRNNQVCHWLILTDSKGLGKSLATHLGNECSVVYYEPG---------IYHINPSHPQEFEQVYQTIFENGKLPQKVIHLWSLDTA
SQDLTTETLEQAQLWGCGSTLHLLQTLVKNPTPPKLWMITRGTQPVLSPTELTVATSPLWGLGRTIASEHPQLWGGLVDLDPQ---GSEDEVEVLLQQII
DKEDHLAV--RNRKIYVRLL--KHIPQES---QPLSRSDATYLITGGLGALGLKTAAWMAEKGARNLVLISRRQPS---EQAQQTIQSLEEL----GTQV
KVLSADISVESDVANILEQIQ-TSLPPLLGVIHAAGVLDDGLLQQTNWERFTKVMAPKVNGTWNLHKLTQHLSLDFFVCFSSMSSLLGSPGQGNYAAANA
FMDAVVHYRR-EMGLPGLSINWGGWSEGGMATRLAHQNRMQTAGISLISPEQGIQVLEELVRTQSTA-QVGV----------------------LPVDWS
------VLAKQFSS-----------ANPSSLLLELLQQETSSEKTDERI----LEKL-----QAAPITERQDILKNYIQKTINPSKISTDDNFVELGMDS
LMGMEVVNKLSGDLDFIIYPREFYERPTIDSLTQYLSAE-----------
>tr|D9WB12|D9WB12_9ACTN Modular polyketide synthase OS=Streptomyces himastatinicus ATCC 53653 GN=SSOG_00518 PE=4 SV=1
------------------------------------------------------------------------------------GQDATPVKSLAEVRAV
AAVPPMDGGPETVHEVTHRVLALMQECLAELARTRLVFVTRGAVASEGDV-TDLAAAAVWGLVRSAQMENPGRFL-LADLDGS----AA-SAAVLPSLP-
-GTDEEQFMVREGTVRVARMMHAPEPSAPARNGSLWGPEGTVLITGGTGGLGRELARHLVERGARHLVLASRRGAEAP------GAAELREELTAHGAEV
SLAACDFADPVAVRELLGAVPAAH--PLTGVVHTAG-VDDGVLDALTPERVDTVLRPKVDAAWHLHEATRTADLAAFVVYSSVAGVMGSPGQANYAAANA
FLDALAQHRR-RAGLAATSLAWGPWAQGTGMTSGLGIERMKRSGTPPLTLEQGLALFDAATGRDEANL--IVMRTAGKAGP-------------------
-------------------STTMFAGAVPPILVRAGRRTAA--DNRAADLAARLADT---REHER-VRLLTDLVRGEAAAVLGHDQVGVEREFDRLGFDS
LTALELRNRLTATTGLRMPATLIFDYPTPAAVADFLATR-----------
>tr|I0J6Y4|I0J6Y4_SORCE Non-ribosomal peptide synthetase/polyketide synthase OS=Sorangium cellulosum GN=pelA PE=4 SV=1
-------------------------------------GRLTGAGQRCVRVFAGEGYEQIEPDLYRIDPGKRGDYARLLREAFGEEGSCGGVVHLFSLDAA
PMEATTAEAAAELVSGSVSAAYLTQALVRH-GFRDAPRLFLVTRGAQGHEAVSVGQAPVWGLGRTIALEHPEVQCTRIDLAPG--A-SEADAARLARELG
AAGPEDQVALRGDDRYVARLVRGRFEAES-ARRFSLRPDASYLITGGLGGLGIALARWMVDRGARHLVLVGRRGPGEAARG---AIEAMEA----AGARV
LVAQADVSRPDDTAGLLATL--DEHTPLRGVVHAAAVLDDHTLLELDEQNFRRSFAPKALGAWNLHALTEGRELDFFVMYSSALSLFGSPGQANYTASNA
FVDALSRERA-RRGLVSMSIQWGAFAEVGLAAADLRGNRLSSRGIASFSPDEGHRALERLLSRPRAEV--------------------------GVVRFD
--------ARRWATFYATAASSLSRERPS-----------AGGGGRAPRLRQALE--------RAALDERQPLERHIAEQVAAVPRIDRRAPFPRLGMDS
LLSLEVRNRLEASLKLGLSATVMFAYPNIAALAAHLL-------------
>tr|E2Q519|E2Q519_STRC2 Modular polyketide synthase OS=Streptomyces clavuligerus (strain ATCC 27064 / DSM 738 / JCM 4710 / NBRC 13307 / NCIMB 12785 / N
-------------------------------------DTLTAAGAAV-----------------TTHPGPAAL-----AAALDAGPPAPGLAF-LPLLPE
PADGSHDGDVHEVHD--AVLETLR-TWLAD-ERLAATGLVLVTRGAVSEGPADLAHSAVWGLVRSAQSEHPGRFVLLDLDPD------RPDGPALA--AA
LASDEPQLAVRGTTPLVPRLTRAAADNPT-PHSNPIDPTGTVLVTGGTGLLGSLVARHLVRHGVRHLLLVGRRGPAAPGAAE-L-TAELTA----LGAHT
TVAACDVSDRAALAALLTTL--PEAHPLTAVVHTAGTLDDGVISSLTPERMDTVLRPKADAALHLHHLTQDLPLSAFVLFSSAAGTFGGPGQANYAAANA
FLDALAQRRS-ADGLPAHSLAWTLWEQRSALRLDADTRRLARSGMPALTTAQGLTLFDAALTTDEPAL--------------------------VPLRLD
--------TR-------ALRSRLRRTPARRS--------AAAEHADSHPLPRRLA--------ALPAPERLRTTRLVCAQAASVDTVEPDRAFRDLGFDS
LAAVALRNRLGEITGLRLPATLVFDHPAPAALAAHLR-------------
>tr|A0A0A4AM47|A0A0A4AM47_DICCH Mycocerosate synthase (Fragment) OS=Dickeya chrysanthemi GN=NM75_07660 PE=4 SV=1
--------------------------------LAEALRARYGDDASVVAAMSAKAFTQHDARRFSVDTQSQASVQTLCEQLAAQQLWPTHIVHAIGADKH
FDDLPVAGPASLLHAGLQSLRHLFVALETVKPGQALRCVNVYTAQAEQVEPQ---QDAVSGYARSINHRFELFTLRS-D-----ADNAAALANDVYQEFV
QPVAGVEVAYRQGIRYQRQAGEITPPDADGMGSQPFVHRGHYVITGGAGKLGLLMAHYLASRYQARIVLSGRSAQPDETVQQQ-WV-----AMREHGAEV
RYIAADVAQEGQAEALIAQAKAAFG-AVDGVLHCAGVASATPITALSDAEFYALIGPKVDGLVALDRATAQEPLSVFINFSSVSAVLGDLGSGAYAAGNR
FMDSHAVWRNGLRTGQTLSVNWPLWASGQMNIEQEDARLFEFSGMAALGQDAGIIALERALLEQRSALLVAVDRSKVARSLRIQAEAMPQTAVSVVTEAP
----------RHQPTAAAMQPG-----------------------DSAYLHS--------------ERALKERISTIT--KLPASDIAVDATFEQLGMDS
VMLMELRAVL-EKEYDGLPKTAPFEFNTTAKLA-----------------
>tr|B1XKC6|B1XKC6_SYNP2 Polyketide synthase OS=Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) GN=SYNPCC7002_A1173 PE=1 SV=1
DWLYQVAWTPLDLPPAPEPSAKLWLILGDRQPIEAQF---KNA-Q---RVYLGQSNHFPTNAPWEVSA---DALDNLFTHVGSQN--LAGILYLCPPGED
PE-----DLDEIQKQTSGFALQLIQTLYQQKIAVPCWFVTHQSQRVLETAVTGFAQGGLWGLAQAIALEHPELWGIDVDDSLP------NFA-----QIC
QQRQVQQLAVRHQKLYGAQLKKQPSLP---QKNLQIQPQQTYLVTGGLGAIGRKIAQWLAAAGAEKVILVSRRAPAADQQ-------TLPT------NAV
VY-PCDLADAAQVAKLFQTYP-----HIKGIFHAAGTLADGLLQQQTWQKFQTVAAAKMKGTWHLHRHSQKLDLDFFVLFSSVAGVLGSPGQGNYAAANR
GMAAIAQYRQ-AQGLPALAIHWGPWAEGGMAN------SLSNQNLAWLPPPQGLTILEKVLG----------------------A----QGEMGV---FK
PDWQ--NLAKQFPEFAK-------THYFAAVIPSAEAVPPTA-----SIFDKLIN---LEASQRAD-YLLDYSVAQIL--KLEIEQIQSHDSLLDLGMDS
LMIMEAIASLKQDLQLMLYPREIYERPRL---------------------
>tr|K9PUU3|K9PUU3_9CYAN Long-chain-fatty-acid--CoA ligase, 6-deoxyerythronolide-B synthase OS=Leptolyngbya sp. PCC 7376 GN=Lepto7376_0247 PE=4 SV=1
EWFYEVQWHQVELPQASEQKEGLWLILGDHLEIAQQF---PQS-Q---IVSLGDEFQ-QHSDHWEVHP---DQFDQLFTSLANTK--LAGIIHGWAIAAE
EQ-----NLDHSQWLTCYTTLQLIQSLQRQQRQIPCWLLTRNSQAVLENKVEGFTQNSLWGMGKTIALEHPELWGIDLDAAIP------NLT-----KLC
NQTKIQHLACRNGSIYCSQLVPQTVTK---TKISAIVPQAVYLITGGLGSIGRRLAQWLDEQGATKVLLLTRRSLATDLA-------DLPK------SAI
AY-TCDIADDHEVQNLFQRYP-----NISGIFHAAGVLEDGFLATQTWKNFEKVFAAKVQGTWNLHHHSLTNPLDFFVTFSSVASIVGSPGQGNYAAANG
FMDAIARYRQ-GQGLPALNINWGPWATDGMAT------ALRNQGMAFLAPEQGLHILETVLA----------------------Q----QTNVGV---FK
PDWQ--QLSRQFPAIAN-------SYYFRAVMGETEEVSTQN-----DIFERLQT---LPTTEQQQ-QLTDYSIARIL--KLDSTQIQPSDNLLDLGMDS
LMVMEAIAHLKQDLRLMLYPREIYERPKL---------------------
>tr|A0A060PJW2|A0A060PJW2_9SYNE Olefin synthase OS=Synechococcus sp. NKBG15041c GN=ols PE=4 SV=1
GWFYRTVWKPIQLGIAQQP-EKQWLILGDREAIYQQF---TKA-K---FVYLGTNNQFSGDDFWQVSP---DSFDELFSHIEREH--LAGVLQICPPIVP
TS-----DLEQGQRSTSATALKLIQALDQQKFAVPCWFVTHQSQRVLESSVEGFAQAGLWGLGQVIALEHPELWGIDLDTTLP------NLV-----QIC
QQNQFQHLAMRRGQLYGAQLQPQAHRA---IKKVPVQSQGTYLVTGGLGAIGRKIAHWLADQGAEKIILLSRHRHPKISI-------DLPQ------NAI
VY-PCDLADESQVEKLFQIYS-----QIRGIFHTAGALADGLLQKQTWENFQAVAAAKVNGTWYLHRHSQNLNLDFFVLFSSVASVLGSPGQGNYAAANR
IMTAIAQHRQ-AKGLPALAIHWGPWAAGGMAT------ALTNQALDLIQPQQGLDILETLLG----------------------K----QGEIGV---FK
ADWS--TLAKQFPDLTH-------SDYFQAVITEEQVPQKNL-----SIFSELLT---LTAEKRAA-YLLEYSVAQIL--KLDRQKIQPHDSLLDLGMDS
LMVMEAIAALKQDLQLMLYPREIYERPRL---------------------
>tr|E8W4K0|E8W4K0_STRFA KR domain protein OS=Streptomyces pratensis (strain ATCC 33331 / IAF-45CD) GN=Sfla_6221 PE=4 SV=1
---------------------------------------------RVVWLLPGKDLVRIDDDRYEADPSDTGHLAAVLLEAGAPGPAGTAV--DWLHALP
LAIDGLDTARWACLDTVAALSRAVADVVR-----------THGRDRPRVWTGPPEAGLLTAATQVPRQELG-TEMNWIDLPGP----DPAPWAAFLPDLL
APAETSAVALRDSFWWHRAVHPVAAPATPRGRETGARSIGTHLVLGGTGGIGAVLAARILRHPENRVVLLSRHAPPALEP-SRDRI--------------
TLVRADLALEEPADLA-DRLAPHLGGGLAGIVHAAGTAAGGLLALRDAETARRGTEAKLRGALLMERLIASHHPGHAVYCSSMASLFGGVGQFDYAAANG
CLDAFAQYGG-DDGTSPTGIGWDVWREAGMALSALGHDGQHQRHLLTLTSDEGAAVFEQAMR------------L-QLPHLMVNT-----------TDLA
------QARSFYE-------RPA-TTSEETPH-----PPTEAAR-------------------PTPGHDRVAQLVDTVALLLGVDDVATDASLYDLGADS
LMLLELADRIEQRFGVDLDLSRFSHRVSVAEISGLIDAAAARDA------
>tr|A0A0Q0JG73|A0A0Q0JG73_PSEA0 Non-ribosomal peptide synthetase/polyketide synthetase OS=Pseudomonas amygdali pv. ulmi GN=ALO41_04851 PE=4 SV=1
---------------------------------------------HVIEVQAGNGYQQLGPNRYELDPLDPLAFSRLIAELDQSGQVATEL--DWLHALP
LSVGGLAAAQWACLDTLSAFLQAWGQRA--------------QKTALRLWNGQPELAALAGITEVAPQEYP-IRCHWLDLPAA----QWGSQALQLASLL
PTSLPRRMAIRDGYLWQPQLQPGPLALPKV-ASNLLPVNGTFLVLGGTGGIGRTLCEHLLRSSQRRVVLLSRRGPQELGD-YAARI--------------
DSVQADIADLARWPKV-LEQLRERYGHFDGVIHAAGTGAGSLIRQRDAHLLSEAMASKTRGMLAVEALIEQMTPGFVLYCSSMSALFGGAGHLDYAAASA
VLDGFAHYRP-N-GENGCGINWDIWRETGMAAASGIGDEAHQRHLAVMSAQEGCQVFDAAMT------------A-QLPQLLIST-----------TDLN
------TARQFYP-------ARH-SGAGLTVV-----DTAPAV---------------------AAETGLPERLHGCLCKWLGVSALDPDDSLYELGADS
LTLLDLIDELQAATGVVFQLSQFSHKVSLREVLALVQSAQGGAA------
>tr|A0A0B8V6Y6|A0A0B8V6Y6_9PSED Thioester reductase (Fragment) OS=Pseudomonas coronafaciens GN=OA77_03975 PE=4 SV=1
---------------------------------------------QVIEVCAGNGYQRLGPDRYELDPLDSSAFSRLIAELTQRA-PLTEL--DWLHALP
LSVSGLAAGQWACLDTVCALLQAWGQTP--------------RTMVLRLWNGDPELAALAGITEVAPQEYP-IRCHWLDLPEP----RLSLYARPLAALL
PALLPRRMAIRDDYLWQTRLQASPLVAPAT-VSNLLPVDGTFLLLGGTGGIGRTLGEHLLQSSQRRLVVLSRSGPDNLLG-YRSRI--------------
DLIAADIADLARWPAV-LDSLRQRYGRFDGVIHAAGTGAGSLIRQRDAQTLAASMASKTLGMLAVEELVKQMTPGFVLYCSSMSALFGGAGHVDYAAASA
VLDGFAHYRA-D-SADTCSINWDIWRDIGMAAAEGVGDAAHQQHLAVLTAQEGGQVFDAALG------------A-QLPQLLIST-----------TRLE
------TARQFYP-------LRH-GAASS-PT-----DIKLAG---------------------QSDTDLRERLQDCLCKWLGVPSLDEEASLYELGADS
LTLLDLIDELQAATGEVLQLSQFSPTVSLREVLMLVQSSETDEA------
>tr|A0A0P9XYT7|A0A0P9XYT7_PSEAV Non-ribosomal peptide synthetase/polyketide synthetase OS=Pseudomonas amygdali pv. lachrymans GN=ALO35_02371 PE=4 SV=1
-------------------------------------------YRHVIEVQAGNGYQQLGPNLYELDPLDPLAFSRLIAELDQSGQVATELDWLHALSVG
G-VVNEQSLAAAQWACLDTLSAFLQAWGQQKTALRLWLLSWQACPVNGQVM-RPELAALAGITEVAPQEY-PIRCHWLDLPTAQWGSQALQLASLLAE--
PTSLPRRMAIRDGYLWQPQLQPSSLALPT-VVSNLLPVNGTFLVLGGTGGIGRTLCEHLLQSSQRRVVLLSRRGPQELGD-----------YAAR----I
DSVQADIADLARWPKVLEQ-LRERYGHFDGVIHAAGTGAGSLIRQRDAHLLSEAMASKTRGMLAV-EALIEQMPGFVLYCSSMSALFGGAGHLDYAAASA
VLDGFAHYRPNENGCVRLGINWDIWRETGMAAASGIGDEAHQRHLAGMSAQEGCQVFDAAMTAQLPQLLTDLNTA-------------------------
---------RKFY------PARHSGAGLTLV-----------------------DT---APAVAAETGLPERLHGCLC-KWLGVSALDPDDSLYELGADS
LTLLDLIDELQAATGVVFQLSQFSHKVSLREVLALVQSAQ----------
>tr|A0A0N0B232|A0A0N0B232_9ACTN Uncharacterized protein OS=Streptomyces sp. NRRL F-7442 GN=ADL09_17820 PE=4 SV=1
-------------------------------------------------MHPAGAFARRGPDAYEADPADPTSLRRLFDALSEDGPVSLDTEWVHALGVS
G-PVGPGTLEHARRACLDTTAALAQALTG-DGSPRVWWLSYGARPVVGAVD-RPELALLAGPVEVAPQES-ALNGHWIDLPDGDLTRWAGHVASVVAD--
RPALPRQLALRQGYWWRPDTLPVPDPAGT-RSLVPAGEDTVHLVLGGTGGIGSAVAAWLLEHTRGRILLLSRKPPEELSA-----------WAHR----V
GLVRADLATMPV-HEVAAR-VADRTPRLDGVVHAAGLGHAGVLVRRDAAAMREAAAVRERGALVV-ERLIAAFPAIAVYCSSMSAWLGGVGHSDYAAGAG
LLGGFAHHRATTETTVRMAIDWDIWSESGMATRVPSADARHQAHLAGLTVEEGKEVFGHALALQLPQLLTDIDAS-------------------------
---------RAFY------GPAEPADRPSRTGPVHR--------------TEGQEE---APGPGGPEERADALARVIQ-DLLGLDELGPEDSLYDLGADS
LTLLSLIDRIEDDYGVEFDLASFSHRVSLAEILKHIEAAL----------
>tr|T2RMZ6|T2RMZ6_SACER Uncharacterized protein OS=Saccharopolyspora erythraea D GN=N599_36415 PE=4 SV=1
DWRYRVVWREAPEPSAPASLPGTWLVLVPDAERHQATRAMTECGARAVTVECGEKDT------------DRAALADRMGRLLSDQPDVRAVVSLLALDER
RHPHH-----PAVPVGLAATLALVQVMSDLDRHTPVWMLTRGAVAAGAERLRRPEQAQIWGLGRVAALEHPRQWGGLVDLPEDPD---DFALRRLCGALA
GGGDEDQLVLRESGALVRRLVRAP-VTA--APVRRWRPRGTALVTGGTGALGPEIARWLAGNGAEHVVLVSRRGADSDGA------AELAAELRELGTEV
SFEACDVADRDAVEAMLGRLRAQ-GREVRSVVHAAALMRLAALADTDLREFADVLAAKVEGARHLAELLDPDRLDAFVLFSSIAGVWGSGDHGAYAAANA
YLDAFAEHLR-ADGRAITSVAWGVWDGARFP-EGVDAEQLRRQGLPLIAPGPALTALQQVLDHDEAVSVADVDWDRFVSLFTS-----------------
-A----RPRPLLDEVPEAA----------------PAPADDGQDEPGSSWPERLAAL----GEADQRAALRALVREQAAFVLGHESIDDGRAFRELGYDS
LTAMELRNRLNAATGLRLPATLVFDHPTPAAVAEHLRSRLVRT-------
>tr|C4RFV4|C4RFV4_9ACTN Polyketide synthase OS=Micromonospora sp. ATCC 39149 GN=MCAG_00543 PE=4 SV=1
------------------------------------------------------------------------------------------MLSLLALDEA
PHPRH-----PFLTVGTTATVTLVQALSDAGVTAPLWCATRGAVSVGADDPPCPERALLWGVGRVAALEQPTLWGGLVDLPASLD---DVGTDRLLAVLG
GGTGQDQVAIRDGGVFARRLGHAG--RD--QASVPWRPHGTVLITGGTGFLGAHLARWAADAGAEHLVLVNRRGPDAPDA------RELADDLSGRGARV
TVAACDVADRSALADLLDRVRAD-GGPLRAVLHAAGTVEYRSLADTTPADLAEAVRTKVAGARNLDDLLAADDLDAFVLFSSIAGTWGSGEQAAYSAGNT
YLDALAEDRR-RRGLPAASVAWGSWGRGGMLAA-DVAAQLDRSGVHAMDPDLAVTALARAVTDDSPTTVAAMDWSRFHPTFTL-----------------
-H----RPSPLLSDLPEVR----------------ALLDTAEPEREAVPLAESLADL----PSDEQAKALLDLVRGQVAAVLGHAEVEPDRAFREVGFDS
LTAVELRNRLKTVTGLPLPVSLVFDFPTPTKLAGHLRAELCPA-------
>tr|A0A0F5A3H8|A0A0F5A3H8_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. MUSC164 GN=VT50_32375 PE=4 SV=1
GWRYGVMWKPVAGRLAAGVLGGCWLVVVRAGEAGGGVGMLAGCGVDVRVVELGAVGR------------GG--VAEELR----ADGSVAGVFSLLAVGG-
-----------D-ELGLLGTAVLVQALGDVGVGGSLWVATRGGVSVGSDGVVVPGQALVWGFGRVAALELPERWGGLVDLPESE-------LGRLAGVLA
G-SGEDQVALRASGVFGRRLTEASG---ATPDDEGWRASGSVLVTGGTGALGAHVARWLVANGAEHVVLTSRRGLDAPGA------VELRDELAASGARV
TVAACDVADRDALAELLASIPA--EFPLTTVFHAAGVLDDG-VDTLDAERLERVVRAKATSAQNLHELTRDLDLSAFVLFSSLAGSVGAAGQANYAAANA
YVDALAELRR-AEGLPATSIAWGPWAEGGMAADEALERRMRRDGVPPMAPESALTALRQALDLDDTATVADLDWGRFLAEFTA-----------------
-V----RPSALFGEVRAAR----------------PAPVAEAAGVGTGTLAERLSGL----TENERTQTLLELVRTQVASVLGHEAVEAGRAFKELGFDS
LTAVELRNRLNAATGLRLPATLIYDYPNATALADHLRGEL----------
>tr|A0A081E9A3|A0A081E9A3_STRFR Uncharacterized protein (Fragment) OS=Streptomyces fradiae GN=SFRA_32280 PE=4 SV=1
--------------EPASSPSGHWLLVTPPTPEGRR-GALARQGATVERLVVDPVAV------------GRDGLAARLGE------RWDGVLSLLGADER
PLPRH-----PALNRAVMGTTLLAQAALDAGCEARIWAVTREAVAVSS-EVPRDAGAQLWGLGRGIALEHPSLWGGLIDLPAVPD---ERAWARAVRRLV
--HGEDQIAVRASGAYGRRLLPAPPAA----SRRTCTPSGTVLVTGGTGALGGHLARRLARGGTGHLVLTSRRGPDAPGA------GELAGELASLGAKV
TVAACDMADREAVRALLDEHRP------TAVFHTAGTPHSAEFTALDETTTAGVYGGKVLGARHLDELTRELGLDAFVLFSSGAAVWGSGGQTAYGAANA
ALDALAERRR-AAGLPATSVAWGLWGGGGMG-EGDGEEFLSRRGLGVMPPEDALEALDRALDREDTTVVADVDWERFAPAFTA-----------------
-F----RPSALISRLVSDG----------------GEAGG-QDAPDGTLFAAGFAAA----GPLERQEMLLGLVRRHVAAVLGHADIGPDRAFKELGFSS
VTAVELAGRLGRECGRKLPPTLVFDHPTAAAVAEHLAELLTPP-------
>tr|A0A0F4ISC9|A0A0F4ISC9_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. NRRL S-495 GN=VR45_41030 PE=4 SV=1
PQRYRIAWEPLTAPA-QPALSGRWLLVTPD-----ACQALAGHGADVVVIRVGAA-V------------ERAE----LALLLPE-GALEGVLSLLALAEG
PHP---------LDAGLTGTLLLLQALGDSGIDAPLWCATRGAVAART--EVRPEQAQVWGLGRVAALEHPQRWGGLVDLPDLG------ALDGLCAVLA
G-DGEDQVAVRGPEALGRRLVPAPAPAT--PTPAPWTPRGTVLVTGGTGGLGAQVARWLAERGAEHLVLLGRRGPEAPGA------DALVDALAALGARS
TLLACDVADRAALERVLERLSDE-GDTVRAVVHAAGLTSDTALMDCTPEELALRTAAKTRGAAHLDVLFEGRPLDAFVLFSSISGTWGSGGQGAYAAANA
YLDGLAAARR-GRGLTATSVAWGPWAGAGMA-DGAVGDGLRRHGLVPMAPAAALSALGLALALDEGEVVAELDRARFVPTFGS-----------------
-V----RDSALLRGLPAAA----------------ESRAADPGTGGDPSLLQRLRRL----SEPEGRKLLTELVRSEAAVVLGHAGFVADRPFREVGFDS
LTAVELRNRLVAATALPLALTSVFDHPTAAALGAHLFAGLSGT-------
>tr|A0A0L8QDG2|A0A0L8QDG2_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces varsoviensis GN=ADK38_38450 PE=4 SV=1
----DVYKRQLAVPP-APDLPGTWLLVVPEDGATGACEALVRHGAEVSVLRVAAG-T------------GRAE----LAGLLPARSDVVGVLSLLAFADA
EAHAD-----AHPSAPLAATLTLIQALGDRELNAPLWCVTSGAVAPVPSVPIDPVQAQIWGLGRVAALELPRLWGGLIDLTGAGE---DGALDGMCAVLG
G-DGEDQVAVRGARLFGRRLDRASVPAR--PAAEVWKPRGTVLITGGTGGLGAHVARKLAAEGAEHLVLLSRRGPRSPGA------AELTAELSALGARS
TVLACDVADRAALTRVLDGLRAE-QETVRAVVHTAGLTSDTRIEHCTPDGVARETAAKTRGADHLDALFDSPSLDAFVLFSSISATWGSGGQAAYAAANA
HLDALAAARC-ARGLAATSVAWGPWSGAGMA-HGDVGRRLRRHGLVPMEPAAALDALQRALTYGESEVVADMDWQGFLPAFLS-----------------
-A----RDSALLRRLPDAA----------------PAATAGSGADAHDAWRRALAEL----PPDERGHRLRELVRAEAAEVLGHGSIDADRPFRDAGFDS
LTAVELRNRLIAVTGLALPLTTVFDHPTATALGDHLLAELTVA-------
>tr|A0A0N0YGC3|A0A0N0YGC3_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. NRRL S-4 GN=ADK82_27980 PE=4 SV=1
GWRYRIDWTPLARAK-SSSLSGQWIVLIPEALRDDACAALAEHGARVTTLVVSAGES------------DRDTLAGSIRRLLDAGGEVAGVLSFLGADET
PDPVH-----AAVPAAVTSTLALVQALDAVELQAPLWCVTRGAVQVSTDRTVSVAQAQVWGMGRVVGLERPGNWGGLIDLPAEVD---ARITDSLCGILS
DAAGEDQVAVRTAGVFGRRLARAPLNGA--DPTAPWNAEGTVLITGGTGALGGHVARWLAGRGAERLVLTSRRGTAAPGA------AELEAELTALGTKV
SVVACDVSDRAQVAELVGRLSQE-GSPVRSVIHTAGISDSVALADTEPAAFADVLSGKTAGAAHLDELLG-GTLDAFVMFSSIAGVWGSARQAAYATANA
ALDALAIRRR-AQGWAATSVAWGQWADSGMA-AGETGEQLTRLGLAPMDPGLAVAALQQAIEHDEAPVTVDVDWSRFATAFTT-----------------
-L----RRSPLIAGLPEVR----------------AALTSTEGAGTADALTRRMLDL----SGPERDHLLLELVQERAATVLRLNAVRPDRAFRNLGFDS
LTAVELRNQLAEATGLRLPAALVFDHPTPTALITYLRGKLLPE-------
>tr|A0A0N0YEZ6|A0A0N0YEZ6_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. NRRL S-4 GN=ADK82_24295 PE=4 SV=1
SWGYRSSWTPLAEGSA--SLTGTWLVVTSATGASNLIHAMRAQGAEVLHCAAGDVL-------------DRVTLS---L-AGTLRTDIAGVLSLCSVDEE
PVAGS-----PE-TTGLAATVTLVQALGDTAVAAPLWCLTQGAVQTSHDGSISPAQALVWGMGRVAGLEHPERWGGLIDLTDAE-------LSRLCGLLA
RACDEDQLAVRPGGVFARRLLPAPP---V-ASGRSWTPEGTVLVTGGTGAIGRQLARWLCGHGAEHVVLIGRRGADAPGA------AELIEELAGPGTKV
TAVACDVADRDALAGLVARLTAD-GDRITAVLHGAGELDDA-MGALTPERLAAALRANVGGARNMQEVTQGLELTAFVLFSGIAGTVGGAGQGAFAAASA
YLDAFAAHRR-SRGLAATSIAWGPWADGGPATDDTFVERMGRRGLAALPTASALPALSRAVAQDSPSLLADIDWALFGPSLTA-----------------
-V----RPSPLIADVPRMR----------------EITRAA----SAAVFRRTAAEL----SEVELGQMLLELVRTEAAGTLGHEAVGAKRPFRDLGFES
LTAVELRNRLSTRTGLRLPVTLAFDYPTPVALAAFLRTEVGDD-------
>tr|A0A0N0HJ24|A0A0N0HJ24_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. NRRL S-4 GN=ADK82_24480 PE=4 SV=1
ELCYEVNWRPLAEPAA--QPTGTWLKITAGGTAAAECATLERQGLDVVTVDVSADLE------------GPDALAERLRA---VDTPVRGVLSLLALAEG
PGDAW-----P-----LTATHALVRALGEADVPAPLWCVTQGAVAVA--EETRPGQAQVWGLGRVAALEHPERWGGLIDLPEEA-------TARLGAVLA
G-TGEDQVALRVGGLLARRLRRAPL---ATADGVGWTPRGTALVTGGTGALGAHVARWLARSGVEHLVLTSRRGRQAPGA------AALEAELAALGARV
TIAACDVADQGALDALLGELDAD-GVRVTSVLHTAGVAQTS-IDETQAHDVTAISAGKTDGARHLDEAFGDTELDAFVLFSSTAGIWGGAGQGAYGAANA
YLDALAERRR-ARGAVATSVAWGPWSEGGMAARDDAEAHLRRRGVRALAPATALSLLRHAIDQRVTCTVADVEWETFALSYTS-----------------
-T----RPSNLLSDIPEAL----------------RAQAPA-AGDGAEELVRRLSGL----SGADRQQALTELVRTHAAVVLGHAAIEADKPFRDVGFDS
LAAVQFRNRLAEATGLAVSATSVFDYPTPAELAEHLRSELGQG-------
>tr|A0A0F5AE34|A0A0F5AE34_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. MUSC164 GN=VT50_13230 PE=4 SV=1
GWRYRVTWTSLTEAQ-APRLSGTWLLAVPESAATDGARTLTERGAEVRQITPTAVES------------DRASLTRLVR----LAGAVSGVLSLLAFDAG
TAPGT-----DG-SAGLVGTAVLIQALGDAGVDAPLWCATRGAVAVGTDTVESPEQALVWGLGRTAALEYPERWGGLVDLPGAE-------LARLAGALA
G--GEDQLAVRAAGVFARRLAHAPL---AAPAVRSWKPYGTTLVTGGTGALGAHVARWLARNGAEHLVLTSRRGPEAPGA------AELRDELAELGADV
TIAACDVADRKAVETLLAAVPA--DRPLTAVMHAAGVLDDG-LDALTPERFATVLGPKADAARHLDELTRDLDLTAFVLFSGIAGTLGDAGQGNYAAANA
YLDALAERRR-AAGLPATSVAWGRWGETGLAADGAIGERLDRGGVPAMAPHAAITALQRALDHADTVAVADIQWDRFAHGYTA-----------------
-V----RPSPLIGELPEVK----------------RLRETGADGSPADALRNRLAGI----SRAEQSLVVLEVVRSGAAAALGHDEVGAGRAFKELGFDS
LIALELRNRLTAATGQKLPATLVFDYPTPAALAEFLCGRIVGD-------
>tr|S3ZCD7|S3ZCD7_9ACTN Putative Oleandomycin polyketide synthase, modules 5 and 6 OS=Streptomyces aurantiacus JA 4570 GN=STRAU_6150 PE=4 SV=1
RWNYRESWTPLNETT-AGTLSGDWLVVVPEGRADSAVALLAEHDARPVTVEMPASAT------------GRDAVAAVLR-VGGPAAALTGVLSLLAADGG
APQGS-----DTASAEAALTLALIQALGDAGVGAPLWCATRDAVAVGADARTAPARTALWGLGRVAALEYPERWGGLVDLPDAT-------VSRLGRLLG
G-AGEDQVAVRGSGAFGRRVVRAPLD--G-GTAGEWAPRGTVLVTGGTGALGRHVARWLAREGADHLVLTSRSGLDAPGA------PELRTELEELGVRV
TVAACDAADREALARLLDGISSENGAPLTAVFHAAGVLDDG-LDAMTPERLDTVFRAKAESARNLDELTAGLELSAFVLFSSFAGVAGGAGQGSYAAANA
FLDGLAHARR-ARGLTATSVAWGPWAGSGMAAEGVAAERLRGGAIPPLEPDHAITALKRLLAQDRTALVADIDWQQYAPAFTA-----------------
-G----RPSRLYVELPEVE----------------RLSATAAAGQGP-DLVAKLASL----QRPEQERLLLDLVCEQVAAVLGYAAVEPTRAFRELGFDS
LTAVELRNRVNALTGLVLPATVVFDHPTPTALADCLRTELAPD-------
>tr|A0A060ZJ32|A0A060ZJ32_9ACTN Acyl transferase OS=Streptomyces iranensis GN=SIRAN156 PE=4 SV=1
DSRYRVAWAPVADRKA---TPRAWMVIVPEEPTKASYGALADAGLDVTTVTLDRVA----------------------------GNLAQGVLSLLPLGNG
TGLEN-----------AAQLAATVRVLASMGNRAPLWVVTRGATGPG--VPEAPEQAMVWGLGRSIGLETPDTWGGLIDIPADP-------WRLLAGAL-
--GVEDQIAVRTSGVFGRRLIRATD------TGRGWRPRGTVLITGGTGAVGVHVARWLAERGAERLVLVSRRGGDAGEL------A------DSVGVPV
EVVACDVTDRAAVAALLE------GRDLTAVVHAAGVLDDG-AGTLTPDRFAAVAGVKVDAVRHLHELTRESGLDAFVVFSSLAGVIGSPGQGNYAAANA
AVDALAEAYR-GQGFPVTSIAWGLWGESGAAD-GHSGRQLTARGIPPLDPARLLASLDWAVGQGDAAAVARIDWDRFRLFH-------------------
------GSTSLYDELLEAR----------------PGPETG-------SAAQSLAEL----PPAERDRALLDLVRGEAAVVLGHALIDPGTAFRELGFDS
LTAVQLRNRLAAVTGLDLPSALVFDYPNVTALAGRLRALLAPD-------
>tr|A0A0Q8ZDX6|A0A0Q8ZDX6_9ACTN Modular polyketide synthase (Fragment) OS=Streptomyces sp. Root264 GN=ASE41_32385 PE=4 SV=1
SWRYRVAWRPYQLPE-EAALDGTWLLVVPERWTDDRARVLEEATRVILVVVPERAD--------------RTVVAELLEA---VGDAPAGVLSLLALDDT
PDKRS-----PG-TRGLLGSMALSQALADNAIHAGLWSLTRGAVAVDGDEPV-AGQAAVWGLLRVAALDDPERSGGLVDLPVDT-------LSRLPALLA
A-GGESEFALRPRAVHVRRMVRAPL---ASVEAPVWQPRGSVLITGGTGALGAHVARDLAREGAEHLVLTSRRGPDAPGA------AELERELTDLGCRV
TIVACDVADRGALAEVMRGIPE--ETPLTAVVHTAGAVDRAPLTKIDADEAVELMHAKVVGAENLHELLGAQPLDAFVLFSSGAGVWGNGGQGPYAAANA
HLDALAERRR-AVGLPATSIAWGAWAGGGMVD-AEVGEQLARRGVPAMEPALAVRALRESVAADETTVVADIRWDRFVPAYCA-----------------
-H----GHRPLIDEIPDVQ----------------TLPAAQDASTAADGLRGELAAL----PAAKRKRRLAELVRTHVVAVLGSDVVRPGRAFRDMGFDS
LTAVELRNRLGSALGAKLSATLVFDHPTPNALADHLGAELFPE-------
>tr|J1ZMI3|J1ZMI3_9ACTN Acyl transferase (Fragment) OS=Streptomyces auratus AGR0001 GN=SU9_32733 PE=4 SV=1
----------------------------TES---DWVDGLLEAGCSVVDVLVDTTDT------------DTAAVTERLKQ---AGPEPVGVVSLLAFDGR
HDTAC-----PS-PRGTAATLALVRALGDAGITAPLWCLTQGAVTTSGDRLGAVEQAQIWGLGRVVALEHPDRWGGLVDLPSTP-------RTQLCAALG
S-TDEDQLALRPVGILGRRLVPDRGDRPA-ARTAPWEPAGTVLITGGTGALGAHVARWAAAQGVGHLLLAGRRGADAPGV------AELRADLEASGASV
TVAACDVADRRAVQELLDGIPA--RHPLTAVFHAAGVLDDG-IADLDTERLETVLAPKTEGARLLDELTRDTELSAFVLFSGFAATVGSSGQAGYAAANA
HLDALAQRRR-ADGLPATSIAWGPWTGGGLVD-EGIEERLLRRGLSAMEPRLAVLGLSALLSDGPANALVDVDWRRFLPSFTA-----------------
-S----RPSPLLREMAQPS----------------QADPGAAGGGAGPTLAERLPGL----TGGERDRLLLTTVRAQVASTLGYDAVSPRQQFKELGIDS
LTALELRNGLQAVAGVALPATLVFDHPTPEAVAGHLSRTILGD-------
>tr|A0A0C2AUT3|A0A0C2AUT3_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. AcH 505 GN=HY68_28805 PE=4 SV=1
--------------------AGRRLVVVPAGSADDAVAELG---PDTVLFEASADGA------------DRTLWAKRLAELTSEGTEFAGVLSLLAPAEE
RHPDF-----ASVPCGLALTLALVQALGDAGLDAPLWCATRGAVSVGDDRLTSPVQGALWGLGRVVALEHPDRWGGLVDLPDTLD---ARAGARLTAVLA
GVDGEDQVAIRGSGLYGRRMTHAAPAVT--TPERPWRGRGTALITGGTGGIGGRVARWMAESGAAHLVLTSRRGEEAPGA------AELRSELEELGAKV
TITACDAADRTALAGVIGAIPA--DLPLTSVFHSAGVADGDSVATLTLRQLDALMRSKLTAALHLHELTRGLDLDAFVLFSSGAAVWGSGGQPGYAAANA
FLDALAEHRR-AEGLTGSSVAWGTWAEVGMATDAEVGERLRRQGVRAMEPALALAALQRMLEDDDTATVASMDWEVFTPSFTA-----------------
-T----RPSPLLAVISEAG----------------QALATDDTETGVPPLRQRLDAL----PTAERARALLEAVRAEAAATLGHDAVAANRAFRDVGFDS
VTAVELRNRLRTGLGLPLPAALVFDHPTPDALARHLGPLIFGA-------
>tr|A0A0D5XQ49|A0A0D5XQ49_9ACTN AstD5 (Fragment) OS=Streptomyces sp. XZQH13 PE=4 SV=1
GWRYRIDWQPVTDRLGATAADGTWLMLVPAGHTGS--GALTAHGGRVVRVAVD--GE------------DRKGLAELVRAVGLDGDAPAGVVSLLPLDER
PDTEH-----PTLSRGTAATVTLVQALDDLGVTTPLWCLTSGAVAVRDGEVRSATQPMIWGLGTVLALDHPRTWGGLVDVTAEPD---TTELGRLVAVLC
GEHGEDQVAIRPAGAYARRMVRAEPLAETTASADGWTPRGTVLVTGGTGGIGAHVARWAAGRGAEHLVLLSRRGRAADGA------DALEAELTALGARV
TVSACDVTDRAALAEVISAVPS--DLPVSAVFHAAGTAQEPRLPESTVAEFAEVGRAKIVGAVHLDTLLADHTLDAFVVFSSGAAVWGGAGQSGYAAANA
YVEGLARRRR-AEGRAATAVAWGAWAGGGMV-DDAVAEEFAEVGVELMRPELAVQALGQAMTRDEGHVVAGIDWSRFVPAYTA-----------------
-A----RQRPLLRELPEAT----------------ALRATG-AGDEDGALRTLLLPL----SPQERLTALTDLVLTEAGQILGHTAIEDGVAFLDIGFDS
LTGLELRNRLDRVSGLDLPQGLIFDAPTAGMIAELMLEALEPE-------
>tr|A0A014MJ12|A0A014MJ12_9ACTN 6-deoxyerythronolide-B synthase (Fragment) OS=Streptomyces sp. PRh5 GN=Z951_46725 PE=4 SV=1
SWSYRIAWDPVATGE-PPILPGTWLVVVPSPQADDGVAALAEHGADPVVVEVD--TV------------ERAELTARLRERMSDDDEYAGVVSLLAWDER
IC-EP-----GTLSRGVAATVALMQAVEEIGLAAPLWCVTRGAVAVRLSEVTSEFQPLVWGMGVVQGLDQPSTWGGIVDLPQTPD---GSTLARLCAVLA
GVDAEDQVAVRASGVFARRMRREPV-----TSAPVWQPRDTVLITGGTGGLGSYVARWAAGHGARHVVLLSRQGAQAPGA------AELEAELTALGSDV
TIAACDVTDREQLAAVLAELPD--GAPLSAVVHAAGLALPEPLSKITLAEFADIGRAKIAGARHLDDLLWERELDAFVLFSSGAAAWGSGGQSAYAAGNA
YLDALAQRRR-ARGLAATSVAWGAWGGGLGTIDEMMGAQWRRTGLMTMDPRLAALAMAHTVGSGTAHVVADIDWERFAPGYTM-----------------
-A----RFRPLLRGLPDVI----------------DLLAEDG----QSELVARLAGL----RPEDQERLLTELVQAEAAAVLGHDA-TGDRPFSEIGFDS
LTAVELRNRLNTATGLRLPATMVFDHPRPSVLARRIRAELGQT-------
>tr|I0UWU6|I0UWU6_9PSEU Uncharacterized protein (Fragment) OS=Saccharomonospora xinjiangensis XJ-54 GN=SacxiDRAFT_0064 PE=4 SV=1
SWRYRVRWTGVPMLEASAPLPGTWLLVDVDPAAGQAAEELLVQGGAQVMRIGIEPGL------------GRVALATRLRRLVEAEPSPAGIVSLLGLPRP
ADPVP-----PTLPVDLVSAVTLVQALGDAAVTAPLWCLTRGAVSTRDDPPADPTQAMLWGLGRVVALEHPERWGGLVDLPSLLA---ARIGSRLRGVLA
GESGEDQVAVRPAGVFGRRLVRAPLGTDVARAAECWRTRGTVLVTGGTGALGVRVARWLASRGAERLVLISRRGPAAPGA------AELVAELAAVGVET
VVVACDVTDRDALREVLDDIPP--TTPLTGVVHTAGVLDDTALTDLSESRIAEVLRAKTQGLATLHQLTRHHPITAFVSFSSISGVWGSGSQGAYAAANA
AADAIAEQRR-AAGLPSTSIAWGAWAGSGMA-SGEAGDYLRRRGVLPMSPEEAMAALEASVGNDDMAAVADVDWANFVPSFTL-----------------
-H----RPQPLLSELPEAQ----------------QAVNSTGDGDERDDLVRQLTAM----PPGERARAVLDLVRSEVASVLGFDQVDPDAAFQSVGFDS
LIAVELRNNLSRSTGLPLPPTLVFDHPTPASVAEHLGTRLSAE-------
>tr|A0A0F2SQG6|A0A0F2SQG6_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces rubellomurinus subsp. indigoferus GN=VM98_31895 PE=4 SV=1
AWRYRITWQPVPEPAAA--PPGRWLLVVPQGIAGEC-EALYAAGATVDLLAVDAATA------------DRTELAER------LTAAVDGVLSLLAVDGR
PRPDA-----PD-TAGLAATLALLQALGDAGVEAPLWCATRGAVSA-ADRPVDPRQAQVWGLGRVAGLEHPRRWGGLLDLPERA-------GARLAAVLA
G-TGEDQLALREQGLLARRLVRDATAGPYGPAPQPWRPSGTVLVTGGTGALGARVADWLACGGAEHLVLASRRGPDAPGA------ADLAARLTALGATV
TLARCDVGDRTAVARLLAELPA--EPPLTAVVHCAGVLDNA-LDSADPAHLARVLAAKAGGAAHLDELTEGIPLDAFVLFSSNAGVWGSGGQGGYAAANA
HLDALAERRR-ARGLPATAVAWGAWADTGLAARETERAYLDRRGVRAMDPDLAIVALQRALDEDDGCAVADVDWRRFAASFTA-----------------
-L----RPSPLLADLPEAR----------------PAEEEA----PPGDAAAALRGL----PAAEQHTALLDLVRAHAATVLGHDAVPATRAFKELGFDS
LAAVQLRNRLAAATGLTLPATLVFDHPTPEALARHLRTGLADD-------
>tr|A0A0F4ISF3|A0A0F4ISF3_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. NRRL S-495 GN=VR45_40780 PE=4 SV=1
SWRYRVTWRALPEGP-PAALDGNWLVLSSDGRSEDATHVLEQAGASVVHLRTTEAEA------------DRAVLADRVRASLDAPGPVTGVLSLLGLDER
PHSAH-----PSVPLGTALNLALVQALGDAGTDAPLWWATRGAVSVGTGGPVSAAQNLLWGLGRVAALEFPQRWGGLIDLPEVP------AAARLCRVLA
GGGDEDQVAVRATGCHGRRLVRSALGDT--EPRRRWRPGGTVLITGGTGGIGAQIARWLARRGAGHLVLVSRRGADAPGA------PELSEELAALGARV
TLASCDVGDLEALRALKDGLEHD-GHRISTVFHAAGAGLLVPLPDTDADEFADTFHAKAGGARNLDLLFDRDTLDAFVLFSSISGVWGSAVHGAYAAANA
YLDGLAEDRR-SRGLAATSVVWGIWNGAGMA-AELAEETLRGHGVLFMPPAVAITGLQQVLDHDETVVVADIDWDRFATVFTS-----------------
-A----RPSPLIGELPEVR----------------AALAAEGAEGAPSALRDRLAPL----PAAERTRTLVDLVRTHAAAVLGHDAVAPGRAFRDLGFDS
LTAVDMRNRLNTATGLRLPVTVVFDYSSATALARRLETGLLGA-------
>tr|A0A0A0NIY2|A0A0A0NIY2_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces rapamycinicus NRRL 5491 GN=M271_13820 PE=4 SV=1
AWRYREGWRPLPDTA-SSALSGTWLVVLAPDQKGDAITALDRHGATVETVVVAPDD--------------PRRWADTLAAHTTATAPVVGVLSLLARDE-
-------------AAGLHRTLRLVQGLEAVGLFAPLWCVTQGAVSVGHDPLTGPAQALVWGLGRVAAQELATRWGGLVDLPQEE-------TVRLCAVLA
A-GHEDQVAVRATGILGRRVVRAPR---LDVLDDGWSPPGTVLITGGTGALGSQVARRLAARGAEHLLLVSRRGDTAPGA------DELVAEVTASGAKA
TVAACDVGDADALRALLASIPP--AYPLTSVFHTAAVLDDA-ITSLTPEQVDRVLRVKADAAWRLHELTRDLELSAFVLFSSLAGTVGMVGQGNYAPANA
YMDALARHRR-SRGLVATSVAWGSWAQGGMAERDAVTELRLRHGVPLLPPESALLALEAALADGETAVIADIDWDRFAHAYTA-----------------
-A----RPSHLLDEISEAR----------------RALGAVGTGDTAAALRDRLADA----KPEERERRLLEAVRGQVAAVLGHEAVGTRRPFLELGLDS
VTAVELRNRLGSVTGLQLPATVIFDFPTVAELVDYLSAQLFSG-------
>tr|A0A0N0YE67|A0A0N0YE67_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. NRRL S-4 GN=ADK82_29745 PE=4 SV=1
SWRYRTHWKSLPAGP-KAALSGTWLVAVTPGQLDGTVGALRAQGAVVEPLVVSGADD------------AERPWAEALAA------AASGVLSLLAQDES
PLTDA-----SA-PAGYAQNLALLQQLEAADSDAALWCVTQGAVSIGRDPLTSPAQALVWGLGRVAAQELPTRWGGLVDLPREE-------LARLCEVLA
A-AGEDQVAVRSTAAYGRRLVRAP----LGALGDGWTPKGTILITGGTGALGSEVARRLAAQGAEHLLLVSRQGGTAPGA------TDLEAELAATGARV
TTVACDVADPEALRHLLDSVPE--DCPLAAVVHTAAVLDDG-LTTLTPEQLDRVLRVKAGAAHQLHEMTKDVGLSAFVLFSSLAGTVGMAGQGNYAPGNA
YLDALAQYRR-AQGLVATSVAWGSWARGGMAGRDVVADTSIRHGVPLLQPERATAALETALAHGDTSVIADIDWERFAYAYTA-----------------
-A----RPSRLLDELPEAR----------------AVLTRD--VTATLTLSERLAGL----APAERERQLRTTVRTQVAAVLGHETVELRRRFLELGLDS
VTAVELRNRLSSATGLRLPATIVFDCPTVHELVRYLGDTLFGG-------
>tr|I0J6Y5|I0J6Y5_SORCE Polyketide synthase OS=Sorangium cellulosum GN=pelF PE=4 SV=1
GCACEVAWRRVEPLPATLPEEGAWLVFSDQRGVGAALKARLARAQRCVRVVAGTSYERVEPDLYRIDPTKPGDYQRLLREALGEEGSCRGAVHLFSLDAA
AVEASAETLSADLGRGSVSAAYLAQALVRHRDAPRLFLVTRGAQAVEEGEPVSVGQAPLLGLGKTIALEHPELRCTRIDLSAAGGE---GEAELLARELG
ARGREDQIALRGEGRCVARLVRSSFEPAPREAAIALRADRSYLITGGLGGLGLSLARWLVEQGARHLALVGRRGPGPE---AQQAIREME----EAGAQV
LVASADVSRRDEVERLFARVEER-LPPLCGIVHAAAVLDDHTLLEQSEESFRRVFGPKALGAWHLHALSEGRALDFFVMYSSASALFGSPGQGNYAAANA
LLDALARERE-RRGLRSMSIQWGVFAEVGLAAAQDRGKRLSSRGMGSFTPVEGLEALRRLLLNPRAEVVVRFDPRQWL------------------ELYP
GTS----GPPFLAEVMAEDT-------------------SHRGAGAAPRALERLKS----APAGERPALLERHLLEQAGSVLRLSKMDRAASLQSLGMDS
LMSLELRNRLEASLGIRLSATILFTYPTAGALAEHLLDRL----------
>tr|I0J6Y7|I0J6Y7_SORCE Polyketide synthase OS=Sorangium cellulosum GN=pelC PE=4 SV=1
GCVYEVAWRQAEPLPPSFPRGGAWVVFSDQGDVGAGLHVRLGAGQRCVRVFAGPGYERIEPDLYRIDPAKPGDYQRLLSEALGEEGLCQGVVHLFSLDAA
PLEATAETLSADLVRGSVSAAYLTQAIVRHRDAPRLFLVTRGAQAALEGEPVSVGQAPLLGLGRTMALEHPELKCTRIDLSATAAE---GEAESVARELG
ARGREDQIALRREGRYVARLVGGALD---RPAPPGVRADGSYLITGGLGGLGLSLARWLVEQGAKHLALVGRRGPGPE---AQQAINAME----QAGARV
LVESADVSRRDEVERLFARVEEK-LPPLCGIVHAAAVLDDHTLLEQSEESFRKVFGPKALGAWHLHALSEGRALDFFVMYSSASALFGAPGQGNYTAANA
FVDALSHERA-RRGLASMSIQWGAFAEVGLAAAHERGKQLSHRGVASFTPAEGLEALRRLLLNPRAEVVARFDVRQWI------------------EFYL
AAA----GLPMFAELIAQRA-------------------SARGDREAPRLRETLAE----AAPHERLTLLERHLCEQAAIVLRLSQTDPRAPFQSLGMDS
LMSLELRNRLEASLGLRLSAILLFTYPNPATLAGHLLAAL----------
>tr|L7UC18|L7UC18_MYXSD Polyketide synthase OS=Myxococcus stipitatus (strain DSM 14675 / JCM 12634 / Mx s8) GN=MYSTI_04325 PE=4 SV=1
DWMYQVGWEAQ-ALPPPEKSPGTWVLFADSRGVARELRGLLARGESCVWVTPGASYRSVGEGAYEVDPRDAEHVRRLLSDALPSAPVCRGVVHLWSLDSA
PNDANPQTLERARHQGTTAMLHLVQALARARDAPRLWLVTQGARSVGPRERVSVAQAPLWGLGQVIAMEHPELRCTRVDLSTDA-A---GASDALFRELS
SASPEDQVALRDGARHVARFLRAAEVP--RDSSARVVADGTYLITGGLGGLGLQVARWLVEQGARHLVLLGRAAPSTD---AEATLGQLR----EAGTRV
EVVRADVSSPEDVARAMAVVDGA-MPPLKGVMHAAGLLDDGVLLNLTEERFATVMAPKVLGAWNLHEATRQRPLDFFVLFSSAAALLGSPGQGNYASANA
FLDALAQARR-AEGLPGLSIAWGAWTGIGLAARASQ--RIEARGLRGMSPDKALAALGLLLGQDRPQVVVSLDLRQWM------------------EFYL
SAA----QSPFFARLAGQLS-------------------SRPSDSGRGKFREKLEQ----AGGSERRALLERHLREQIAAVLRMERLGPRVALGSLGLDS
LMGMEIRNRLEASLGLKLSATLVWAYPTLVALVAFLSERL----------
>tr|I0J6Y6|I0J6Y6_SORCE Polyketide synthase OS=Sorangium cellulosum GN=pelE PE=4 SV=1
ECVYAVEWHRGELAPAASPRGGAWLVFLDQKGTGTALRELLARGEASVGVLPAERYARLQPDLYQIDLAEPEHYRRLLREAFGDEEACRGAIHLFSLDAA
PWEQTAETLDADVTRGSLSALYVAQALLRRRDAPRLWLVTRGAQKVGAGDGVAVSQAPLWGLGRTIALEHPELRCTRVDLSPAASA---EEVTALVGELW
SQDGEDQIALRDHGRHVARLVQTNFNR--QERGVRVRPDGAYLIAGGLGGLGLTVARWLVEQGARHVALMGRSAPSAA---AEEAISAMK----AAGAEV
LVVRADVSRHDDVARTLAEIDAR-LAPLRGVVHTAVNFDNHPVLGLSEEHFRRALSAKMHGAWNLHALTSSRECDFFILYSSVSVLLGLPGLGNYLAANA
FLDALAEQRQ-RAGLCGMSIQWGVFSEAGVAAARDSSQSLSDRGLGSLTPIEGTRALSRLLGRPAPNVVARLNARQLF------------------EFYT
LMA----QIPFYSRLRQDSA-------------------ASAGAGEAGRFRRTLDA----AAPGEQRKLLEEHLREQVGKVLHMARIDRDAPFSGFGMDS
VMSLELRNRLEVSLGLKLSATLLFTYPSLAALATYLMTAL----------
>tr|L7UGQ3|L7UGQ3_MYXSD Polyketide synthase OS=Myxococcus stipitatus (strain DSM 14675 / JCM 12634 / Mx s8) GN=MYSTI_04326 PE=4 SV=1
GSVFTVAWQRTEALPA---ASGTWLVFSDRGGFGEELQSLLTRGGACVGVVAGSAYERVSADLYRINPASPEDYRRLLRESFGEDGRCQGVVHLLGLDAA
AFSSTSATLASDLSHGAVSATYLAQALVRQRDVPRLVLVTRGARSVVEGDAVAPAQASLWGLGQTLATEHPELECTRIDLAPVPDA---RDASLLLSELV
AKGHEDQVALR-EGRHVARFVRGGFEPPP-AARPGIRADASYLITGGLGGLGLSVARWLVEQGARNVALVGRTAPSAR---AEEVIRTLE----AAGARV
RVSAADVSREEDVERLLAELGAN-LPPLRGVVHAAGLLEDHTALELSDAHFHKVAAPKIQGAWNLHARTLGQPLDFFILYSSAAVLLGSPGQGNYAAANA
FMDALAEQRR-ALGLPAMSIQWGAFSEVGLAAAVDRGDRLSYRGVGSLTPAEGITALSRLLEHPRPVVVLRLDARQWF------------------EFYP
RTA----SVPFFAELPREAA-------------------PRSGSAQGTSLKQALES----APPAGRLDLLEGHLREQLGRVLRIARIDRTAPFKSIGVDS
LMSLELRNRIEASLGLKLSAALLFTYTHTASLAEHLLERL----------
>tr|A0A060ZMX1|A0A060ZMX1_9ACTN Beta-ketoacyl synthase OS=Streptomyces iranensis GN=SIRAN1402 PE=4 SV=1
SWRYHVTWNRVPDPAS-VALTGTWLLAVPAGGLVDAVRGLETHGATVVTVEVA-EA-------------DRAAVAARLAEA-TAGGTPAGVLSLLGLPDA
PHP-----AHAGVPMGLALTLALVQALGDTGVDAPLWLATRGGVSVGGDALDSPAQAAVWGLGRVAALEHPQRWGGMVDLPDTVDG---RVTTRLCGALA
GRDEEDQLALRPSGVFVRRLVRAAEHR---GSGPAWTPEGTVLLTGGTGGVGAQIARRLAQAGAEHLVLTSRRGPEAPGA------DKLKAELTELGAKV
TVAACDVADRAALEALVRRVEAE-GPPIRSVLHIAGAGVLVPLADTDLAEFADTAEAKVAGAANLDALFDRDTLDSFVLFSSISAVWGSGEHGAYAAANA
YLDGLAEHRR-ARGLTATSVVWGIWSPGGMAAN-LAEEQLRGRGIPFMSPRLAIDAFWQVMERDETVVVADVDWERFVPVF------------------T
SA----RPSPLIGQVPDVA-RILAADA----------DTRADATGESSSLRDRLTEL----APADRRAAVLSLVGSQIATVLGYEAVDATRAFRELGFDS
LSAVDLRNRLGTATGLRFPVTVVFDYPSAEELAGHIGAELFPDD------
>tr|M3AT83|M3AT83_STRMB Beta-ketoacyl synthase (Fragment) OS=Streptomyces mobaraensis NBRC 13819 = DSM 40847 GN=H340_29696 PE=4 SV=1
SWRYRVDWQPISLSEPTAPGAGPWLIVAPS-QWVRACLALEEAGVPAVLVAGP-RP-------------GRSDLAELLRSCRG---APAGVLSLLALAER
PA---------------EASLALLQALLDAGFDAPLWCATRGAVSCGEDPVVSPEQAAVWGLGRVAALEHPEVWGGLVDLPAAPEG---REVGPLPAVLC
GDAGEDQVALRPAGVLGRRLVPDAASAG--GTGEGWRPDGAVLVTGGVGRLADHVVRWLAARGAEHVVLLDSDGAGGRRE------AELAVEVAEYGSRL
TVVRTP---------------EE-AARVRTVVHTSLPGVPAPLADVTPDDLTSAVS----AAVALGEPAGA-PVETVLFFSSLAATLGSREHGAHAAANA
CLDALAQQHR-PDGPRMVSVGWGIWDLDGDLAL-RQTGLSRRQGLPPLEPRLALGALHTLLDGGGGHVVADVEWERFAPLF------------------T
LS----RPTRLLDGVPAAR-RVLEAGP----------EAG--DGADVAELRRELAAL----PARERVGALLKTVRAQVAAVLRYQDVDPERAFKDLGFDS
LVVVELRNRLRAATGLRLPATLVYDYPTPRALAEHLLERILPDG------
>tr|A0A0N0YHB5|A0A0N0YHB5_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. NRRL S-4 GN=ADK82_24125 PE=4 SV=1
DWRYEVAWRPMPEAA-TSSLSGHWLVIVPE-GLVLACLSLAAHGARTHSVDAG-AL-------------HRDLF-----ADHLP--GIEGVLSLLTLDRV
RHA-----DHPDVPRGYAATVALLQALGEAGVPAPLWCATRGAVQVGPDVPDGAEQAMAWGMGRVAALEHPDRWGGLIDLPATLDA---RTGAMLSGALG
GAGDEDQLAIRPSGTFVRRLNRARLGAA--TGSRTWDLAGTTLITGGTGALGGHVARRLAGDGAEHLLLVSRRGPDAPGA------TALRDELTALGARV
TVAACDAGDRAALADLLAAVPAE---PLTSVVHTAAALDDGLLDTLTPDQLGRALHAKARAAQNLDELTRD-SLSAFVLFSSFGGIVGTPGQGNYAPGNA
FLDALAQQRR-AQGLVATSIAWGAWGGGGMAEG-AFGDVLNRHGLREMDPEAAAGAMRQAVEHDATCLIADIDWERFFVAF------------------T
AT----RPSPLLADVPEVR-RIAQEGN----------GSAG-GAEEPSALAQRLAGL----DDADQDAVLLEAVREQVAAVLGFEAVNAKRAFREVGFDS
VTAVELRNRIGARTGLRLPVTLAFDYPTPVRLAAFLREQLVPDG------
>tr|A0A0F5A286|A0A0F5A286_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. MUSC164 GN=VT50_34800 PE=4 SV=1
TWRYRIGWQPLDGQRPL-TLPARLLVAVPT-EAAQAITGLTALGVEVAPVGAD-DT-------------DRTRLAARINEALDTGA-PGGVVSLLGLDEA
PHP-----EHPDVPTGLATTLDLVRALGEAGVEAPLWCVTRGAVSASRDRPEAPAQALVWGLGGAVALEHPQRWGGLVDLPETLDE---GALRALARVLT
GQDGEDQLAIRASGVLARRLRRAGTTR----SGERWQPRGTVLITGGTGGVGAQIARGLADEGAEHVVLVSRRGPRAPGA------AELEAELAGRGARV
TVAACDVADREALARLLHQITQD-GAPLTAVVHTAGALDDATVDALTPERIEAVLRPKVAGARHLHELTRELDLDAFVLISSIAGTVGAAGQGNYAAASA
YLDALAQLRR-ADGLPATSVAWSAWAGGGMIDGEVA-DQLRRRGAPPIDGARALELLRQTVAQGDGFVAADIDWGRFAPAL------------------S
AT----RPLPLLADLPEAG-ATGQDPA----------GAERGA----AALRTRLAGL----GPADRHTALVELVSEQAAAALGYGAVETGRAFKELGFDS
LTAVDLRNRLNAATGLRLPVTLVFDYPTADDLAVLLRDELLPSG------
>tr|A0A0M8W0E0|A0A0M8W0E0_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. NRRL WC-3618 GN=ADL01_17985 PE=4 SV=1
ALRYQITWKPLPGGS-GPALQGAWALVVPD-GWCAAAEAMAAAGTDVRRVD-E-AA-------------DRTEMTKLLRDL-----PLAGVLSLLALDER
SYA-----QSASFTRGMAATLALTQAVVDAEVGGRLWIATCGAVSVGAESVRGVAQSQAWGFGRVVGLEHPEVWGGLIDLPEATGA---VPASARAHLTT
EDFTEDQLAVRPSGALVRRLVRAPRR-P--APAGQWQPRGTVLITGGTGALGAHVARWCAGGGARHLVLTSRRGPDAPRA------AELRAELEELGAEV
TIAACDVADRDALAGLLAEIP----APLSAVVHAAGLGQDRMIDETGPADFAEIVTAKTAGAAHLDELLGG-PLDAFVLFSSIAGVWGSGGQAAYAAANA
FLDGLAERRR-AQGRAVTSVAWGPWAGSGMAGDD-AAAHLRKRGLPVMRPESAVAALRHALGVRDALTVADVDWERFAPAF------------------T
VR----RPSPLLDDLPEAR-RALDAAS----------GVSGATDDAAAALRERLAAA----SADERERTVLKLVREEVAAVLGHEAVREDRAFKDFGFDS
LTAVELRTRLNAATGLSLPSTLVFDHPTPGELSRQLLAELLPDS------
>tr|A0A0M9ZUY1|A0A0M9ZUY1_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. NRRL WC-3618 GN=ADL01_17495 PE=4 SV=1
RWNYRESWTPLTEAA-AGKLTGDWLVVVPE-GWSAAVALLAEHDARAVTVA-H-AT-------------GRDALGAALRAA-----AFSGALSLLSAADD
--H-----DSDAVPPEVALTLALIQALGDAGVDAPLWCATRDAVAVGHDAHIAPGRTALWGLGRVAALEYPERWGGLVDLPDAADT---AAVT------G
AWAGEDQVAVRGSGAFGRRIVRAAAPLE-GDKAGEWTPRGTVLVTGGTGALGRHVARWLAHEGAGHLVLTSRSGPDAPGA------LELRTELEELGVRV
TVAACDAADREALARLLDEIGNGGGDPLTAVFHAAGVLDDGVLDAMTPERLATVFRAKVETARNLDELTAG-DLSAFVLFSSFAGVAGGAGQGSYAAANA
FLDGLARARR-ARGLTATSVAWGPWAGSGMAAEG-AAERLRGGAIPPLEPDRAIAALKRLLTQDRTAMVADVDWQQYAPAF------------------T
AV----RPSRLYTELPEVE-RLSAAAV----------ADGGGAAGQGPDLVAKLVSL----QRAEQERLLLDLVCEQVAAVLGYAAVEPTRAFRELGFDS
LTAVELRNRVNALTGLVLPATVVFDHPTPTALADCLRTELAPDT------
>tr|A0A0M8W4C5|A0A0M8W4C5_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. NRRL WC-3618 GN=ADL01_15110 PE=4 SV=1
ALRYRVSWKPLGQAP-TARLDGTWLLVVPD-RWTDAVEVLGGRGADVRTVA-G-EI-------------DREEFAERLRKE-------AGVLSLLAVDE-
--A-----VRGGVSRGLATTVTLVQALHAADLGAPLWLAGRSAVTVGGDPAPRYVQAALWGLGRVVAVEYPALWGGLVDLPGTPDG---RALD------G
AWAEEDKLAVRGSGVFARRLVRDTSRGA-ADGGDTWTPHGTALITGGTGAVGGHVARWLAAHGARHLVLTSRRGPDAPGA------AELLAELQELGAQV
TLTSCDAADRDALAGVLDAIP----DPLTAVFHTAGVLDDGVLDGMNAERLATVFRAKVESARHLDELTRD-DLSAFVLFSSFAGLSGGAGQGSYAAANA
CLDALAEHRR-AQGLNATSVAWGAWAGGGMAADG-AAERLRGGAMPPMESRAALAALRRALGHEQPTVIADVDWEQYLSGG------------------P
GV----ASDPLFGDLAETR-ALRDRAA----------RT--NGEAEGPDLARRLAEL----SGPERERFLEDLVRTHAADVLGYEQVEPGRAFRELGFDS
LTAVELRNALGAATGLPLPTTLVFDHPTPAALAAHLKAELATDG------
>tr|V6U896|V6U896_9ACTN AMP-dependent synthetase and ligase OS=Streptomyces sp. HCCB10043 GN=P376_4933 PE=4 SV=1
RLRYRVAWAPLPPVAD-GAPTGSWLVVVPP-TRVVGMVMLEGLGMRTRIVEANSA-----------------DYVDTMRRATAE--EFTGVLSLVALDPR
KRP-----GFPVLTEGTAATLALVRAHGEIAAGPPLWCVTSGAVSIGPDPLRAPQQAVIWGLGHAAALEHPDRWGGLVDLPEVIDA---RTGPALFGVLN
GPSGEDQIAVRSAGVFGRRLSESPLRTE-P-TRRDWRPRGTVLVTGGTTGLGRHAARWLAEAGAEHLLLTVDGDPQATHV------HDCVAELTELGVGV
TVSAADISSRAGVAELLAESPSR---ALTAVVHAADLARTMPVGDIDADALREVLSVKADSALYLDELLGD-PLDSFVVFSSAAGVWGGGGQGVAGAVNA
FLDALVEQRR-ARGLSSTSLAWGVIEGLGVAADPAVQQLLRRRGVTPMASEVAVGALSAAIQSDDGVAVADIDWSTFVPAF------------------T
SS----RPSPLLSDLPEVR-RVTEAAG----------SA-P-QAETDAGLANQLAGA----NEAEQTRILLKLVREQAAAALGQEQVKPRQAFQEMGFDS
LAAVTLRNALAAAVGASLPATAIFDYPTPAALVEYLRDELVADQ------
>tr|A0A0J7YRX8|A0A0J7YRX8_STRVR Uncharacterized protein (Fragment) OS=Streptomyces viridochromogenes GN=ACM01_46185 PE=4 SV=1
RLRYRVGWTPVPHAST-GTPGGALLVLAPP-GGVARIMALDGQGRRSRLLAAHGE-----------------DPADALGEVLGD--EFTGVLSLLALDRR
TRP-----ESPALTEGTAATLALLRALGAGTVGLPVWSVTSGAVSVGPDRLRAPEQAVVWGLGRAVALEHPDRWGGLVDLPETLDD---RTVRALLGVLG
GASGEDQVAVRSAGVFARRLLESPLRNE-P-RQADWQPRGTVLVTGGTESLGRHAARRLALAGAEHLLLTVDGDPDASDV------QDLVAELTGLGVGV
SVSTADISNRAGVAELLADPAGR---ALTAVVHTVDSAGMLPVASTDVDELGKALRVKADAALYLDELLGD-PLDAFVVFSSAAGVWGGGGQGVTGAVNA
FLDTLVEDRR-QRGLAATSVAWGVVEGIGVAADPAVQEQLRRRGVLPISTDLAMTSLAAALRSDDGVAVADIDWSAFVPAF------------------T
SV----RPSPLLGDLPEVR-RLAEAAV----------EAAA-EAEAGSALVQSLAGL----SEADQKRALMKLVRERAAAALGHEEVKPRQAFQEMGFDS
LSSVTLRNTLAAAIGESLPATLVFDCPSPAALVDFLHETLAGTD------
>tr|Q7X4R5|Q7X4R5_STRHY ShnC (Fragment) OS=Streptomyces hygroscopicus PE=4 SV=1
RLRYAVTWRPLDREVS-RVPAGRWLAVLPP-GVTAELIELGAQGLDVVPFTVPSAF-------------TRTGLTARL-SDIAE--QPAGVLSLLALDGE
Q----------DVIDTVARTLALVQALGDAGVNGPLWCLTRGAVNTGIDTAGEPGDAAIWGLGRAAALEHPDRWGGLIDLPATADA---HTAQYLVGALN
GTAG-DQLAVRRPGLYSRRLVRKPASQT-P-ADGGWRPHGTVLVTGGAEALGIHASLWLARSGARRLIVTTTAQAPADAV------TELQGKLAAAGVET
TVVSCADADRETLARLIAETPRE---PLTAVVHAADAPWTSAVADTGHADLTEVFAGKVDTAVWLDELFTA-PLDAFVVFSSIAGIWGGGGQGVSGAAGA
VLDALVDRRR-GRGLAATSIAWGALDGIGLGMDEAAAAQLRRRGVLPMAHQVAVTAFEQAAEAREKATVADMDWEAFIPAF------------------T
SA----RVSPLFADLPEAA-AALRSSQ----------PD-A-NGDITSSLVDSLRDV----PQAEQNRLLLRLVCGQAATVLGHESIGPLQSFQEVGFDS
LGAVNLRNSLHVATGLRLPATLVFDYPTPDAVVGFLRSELLTET------
>tr|A0A0M8VYX3|A0A0M8VYX3_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. NRRL WC-3618 GN=ADL01_17460 PE=4 SV=1
SWRYQVAWQPLA-GALPTRLTGRWLVVRPE-NWATGVRALAAAGADVVELTTG-EL-------------TREALTERLREAAA---GLAGVVSLLSLDES
EQD-----THGVVSAGLVGTVALVQALGDAGTSARLWAVTRGAVATDRDQPARPAQAQVWGLGRVVALEFPDRWGGLVDLPENPDG---RAASQLP---G
AVGDEDQLAVRQAGVLVRRFVRAPVGAG---ETREWAPRGTALITGGTGAIGGHVARWLAREGAEHLVLTSRRGLDAPGA------VELQAELEELGAKV
TIAACDVADRDAVAGLLGRLTED-GHILRSVFHAAGVGQGQPLDAMTAADVAEVLEAKVAGAAHLDALLDSAGLDAFVLFSSNAGVWGSGSQGAYAAANA
HLDALAEQRR-ARGLTATSVAWGLWAGSGMAGE-DGEEQFRRRGLRPMAPNLAVAALAQAVAYDETFAVADLDWERFAAAF------------------T
SA----RTSPFIGDLPEVR-RYVESVA----------VEPAGGDDAADELRGRLVPL----TEPEREVILLDIVRSHAAAVLGYESIDAHLAFRELGFDS
LTAVEVRNRLNKATGLRLPATLVFDHPTSVALAQYLRTELLQDD------
>tr|S3ZC67|S3ZC67_9ACTN Putative Oleandomycin polyketide synthase, modules 5 and 6 OS=Streptomyces aurantiacus JA 4570 GN=STRAU_6729 PE=4 SV=1
SWRYQVTWQPLA-GTLPTGLTGRWLVVLPE-SWAAGVRALAAAGADVAELPSA-ES-------------TREALAGRLREAAT---GLAGVVSLLGLDES
PHD-----AHGVVPAGLVGTVALVQALGDAGIGARLWVLTRGAVATDRDQPARPAQAQLWGLGRVAALECPDRWGGLVDLPENPER---RAASQLP----
-AGDEDQLAVRQAGVLVRRFVRAPLAAG---ETRQWKPRGTALITGGTGAIGGHVARWLAREGAEHLVLTSRRGPDAPGA------AELQAELEELGAKV
TVAACDVADRDAVAGLLGRLTED-GHTLRSVFHAAGVGQGRPLDGTTTADIADVLKAKVAGAEHLDALLDASGLDAFVLFSSNAGVWGSGSQGAYAAANA
HLDALAEQRR-ARGLTATSVAWGLWAGGGMAGD-DGEEQFRRRGLRPMAPGLAVAALAQAVAYDETFAVADLDWERFAPAF------------------T
SA----RTSPFIGDLPEVR-GYLESVA----------AEPAGGDDAAAQLRRRLAPL----TEPEREVILLDIVRSHAAAVLGYESIDAHLAFRELGFDS
LTAVEVRNRLNKTTGLRLPATLVFDHPTSVALAQYLRTELLQDD------
>tr|A0A0F5A2M7|A0A0F5A2M7_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. MUSC164 GN=VT50_36375 PE=4 SV=1
DWRYRVVWKPIVESGAGPKLTGTWLAVVPA-GWVHDALVLARSGATVVPLASA-GA-------------DRVTLAEDIRAAVRHAASVAGVLSFLALDE-
--A-----VHQAAPAGAAATLTLVHALSDLAMDLPLWLMTRGAVAVGRDALPSPLQSMVWGLGRVIGLEHPQWWGGLIDLPDVLDD---RAARRWLAAL-
SPADEDQVAIRTSGAFVRRLVRARTGEPSGALGGAWRPRGTVLITGGTGALGGHVARWLAEAGAAHLLLVSRRGPAAPGA------AGLVAELEAAGTSV
TVAACDVADREAVRTLLATLP----EPLSTIVHTAGSGGDLPVAETRLESFADVLDAKVTGARCLHELTRE-ELDAFVLFSSAAATWGSGGQGSYAAANA
YLDALAEHRR-ALGLAGTSIAWGAWADAGMAVVD-AEEMVRRRGLRSMPPELAVVALQQAWDADEASTVADVDWERFVPGF------------------T
AA----RPRPLLMDLPEAA-RAIEATR----------P----VGENASAWLTQLTEA----SVEERERSLVELVRTHVAAVLNYKDIAANRALKDLGFDS
LTAVELRNRLNAVTGLALPTTVVFDHPTPAALVAHLRVQLFGQD------
>tr|A0A0F5A858|A0A0F5A858_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. MUSC164 GN=VT50_27180 PE=4 SV=1
RHLYNVVWKPRPQSGPSPAPSGTWLTVVPA-SRITAVAELTRRGVRVVRLDAA-DT-------------DPAALADRLAAS-SADGPVAGVLSLLALDER
PHP-----EHPAVPVGLALTGALAEALRGDDVPARLWCATRGAVSTGGDRLESATQAQVWGYGRVVALEQPERWGGLVDLPESVDE---RALDRLAAVLA
GPDDEDQVAIRATGVFVRRLVPAPRTAA-TAAAEPWTPHGTVLVTGGTGALGRHVARWLADHGAERLVLLSRRGPDAPGA------AEIVAELSGTGTAV
TVEACDVADRHALAALVEKLAAN-GSPVRAVVHSAGISQE-PGTGTELPEFARIVAAKTAGAVHLDALFGEDPLDAFVLFSSIAGVWGSGGQGAYAAGNA
FLDALAEARR-ARGLPATSVAWGPWADGGMAAEGDAEEQLRRRGLPPMAPESNMVAFQRVLSREETATVADVDWERFAPAF------------------T
AA----RPRPLIDDLPQVA-KALRGDD----------SEPTAAADGAPALRDRLAGL----SAAEREDAVLELVRTHVASALGHAEVEAGRAFNELGFDS
LTAVELRTRLGAATGLKLPASLVYDYPTPAALAEHLLAELVPDG------
>tr|T2RMS4|T2RMS4_SACER Uncharacterized protein OS=Saccharopolyspora erythraea D GN=N599_36110 PE=4 SV=1
SWRYRVAWRPVPEPPA-AGLRGTWFVVAPS-DWIDQCASLEQRGAQVARIDAA-EA-------------DATSLSAELAAE-----ERGGILSLLALTEG
THP-----LHPSAPLGLTANLALVKAVADAAAGTPLWLLTSGAVSTGDDPVRDLGQAAVWGLARTVALELPRQWGGVVDLPADAGE---HATDRLCAVL-
AAGAEDQVAIREPGVMGRRLVRAPLAET--AVTREWRTSGTALVTDGTGPMGARVAAWLVEQGAEHLVLTVDDDTDADH----------AALEAELGVPV
TVAACDVADRDALASVLDGIPAD---PLTAVVHTAGVLGAGALLEAGPAEFAATARAKVRGALNLHELTLD-DLAAFVLFSSVAGVWGGSEQGAYGAANA
VLDALADRRR-ALGRPVTSIAWGPWADAGMGAAEARREQLRRRGVLPMPSERTLGALRDALLHGDTATVVDVDWERFAPAF------------------N
AA----RPSALLAELPEVR-RVLDAAN----------AEAA---EGGQEFAALLAGL----PQDERELRLVELVRREVAAVLGHEALPAGRAFTELGFDS
LAAVGLRNRLGAATGAKLTASAVFDHPTPERLAGHLLRQLAPPR------
>tr|M3D1X7|M3D1X7_9ACTN Modular polyketide synthase OS=Streptomyces gancidicus BKS 13-15 GN=H114_04117 PE=4 SV=1
GWRYRVVWQPRELP--AGSLHGTWLLAVPE-TLTLRTRALTKAGADVVRLVPD-NA-------------DRVVLAERLAALTSG--PPAGVLSLLALDGA
PDK-----RSSGVSRGLLASMALSQALADAGLVTPLWAVTRGAVVAG-TTEPDAGQAAVWGLLRVAGLDDPERAGGLVDLPAGDDA---HGLLPHLTVLG
ERGRETEFAVR-GGVYVRRMVRSPRDEGPTTARPGWKPRGTVLVTGGTGALGAHVARDLAREGAEHLLLTSRRGPDAPGA------EALREELTALGCRV
TVAACDVADRAALAALLDGVPEE---PLTAVVHTAGVVDRAPFTDIDADEAVDLVHAKVVGAQHLHELLAG-PLDAFVLFSSGAGVWGNGGQAPYAAANA
HLDALAERRR-AAGLPATSIAWGAWAGGGMVDA-EVGEQLLRRGVPAMEPGLAVRALREAVADGDTTVVADIRWDRFVPAY------------------C
AH----GHRPLIDDVPEVR-DLLARRH----------EEEAQDTTAADGLRGELAAL----PPAKRRRRLVDLVRTHVATVLGSDGVRTGKAFRDMGFDS
LTAVELRNRLGSALGTRLPATIVFDHPTPNALAAHLDDELFPED------
>tr|J1RV89|J1RV89_9ACTN Modular polyketide synthase OS=Streptomyces auratus AGR0001 GN=SU9_33893 PE=4 SV=1
GWRYRIVWRPQPEP--EGELEGSWLIVVPA-DLVQATSGLGDRA---RIMVSA-TA-------------DRAELLAQLAALAAA--EPLHVLSLLALDDR
DAG-----GHRGVPGSLLSTLALTQALAETEVKARLWAVTQGAVSTDASDPRHPGQAAIWGLARVFGLDHHERWGGLVDLPGTLDE---HALRRFLSLL-
DGGSQDEYAIRPSGVHVRRMVRAPLDPS--AVVEPWQPRGTVLITGGTGALGAHVARALAAGGAEHLVLAGRRGPDAPGS------AELSAELTALGARV
TVAACDVTDRAAVAKLLDSFTDE---PLTAVVHTAGVVGEAPLDETSLDDAMAAVHAKVSGAWHLDELLAD-PLDAFVLFSSGAGVWGNGGQGPYAAANA
ALDALAEWRR-AQGRPATSLAWGAWAGGGMVDE-AVAEQLRRRGVPAMDPGLAVHALREAVDHGETTVVADIRWDRFLPAY------------------T
VS----GPRPLLDELPDVR-QLLAGQE----------EQAD-AGEKGSDLPDRLAAL----PEPKRKRMLLDLVRTHASAVLGHDAVRPARAFRELGFDS
LTGVELRNRLNAATALTLPATLVFDHPTPTALAEYLRDALLPPE------
>tr|A0A086GQY1|A0A086GQY1_STRSC Modular polyketide synthase OS=Streptomyces scabiei GN=IQ62_28880 PE=4 SV=1
DWRYRVAWRPYTAP--EGALDGEWLLVVPE-AVTARTRALEESGAGVVPVVPE-QT-------------DRAVLAELLDAAAAG--PPAGVLSLLALDDE
PDK-----RSAGVSSGLLASMALSQALTDTALSTGLWTLTRGAVAVDDGDEPNSGQAAVWGLLRVAALDDPERSGGLVDLPADGSA---E-LLSHLPAL-
--GGDSEFALRPTGVRVRRMVRSPLVGAGSDVPPVWRPRGTVLVTGGTGALGAHVARELACEGAEHLVLTSRRGPDAPGA------AELERELTGLGCRV
TVAACDVADRDALAALLESIPAD---PLTAVVHTAGAVDQAPLTRVDVEEAVDLMDAKVVGAENLHELLAG-PLDAFVLFSSGAGVWGNGGQAPYAAANA
HLDALAERRR-AGGLPATSIAWGAWAGGGMVDA-EVGEQLLRRGVPAMEPRLAVRALRESVAAGDTAVVADIRWDRFVPAY------------------C
AH----GHRPLIDEIPDVE-AMLTTRQ----------AEDADRDGAMTALRGELAAL----PEAKRRRRLTDLIRTHVTAVLGADGVKPGRAFRDMGFDS
LTAVELRNRLGAALGTGLSVTLVFDHPTPNALADHLGAELFPAD------
>tr|X8EZC8|X8EZC8_MYCUL Polysaccharide biosynthesis family protein OS=Mycobacterium ulcerans str. Harvey GN=I551_8209 PE=4 SV=1
SWRYQVTWLSSPTTPSSTTLSGIWLLIVPS-EPVIGCAALEAHGALVTIIFEP-DF-------------NRSLMGASLKDIG----HISGVISFLGIHGS
EF----------SDSGAVKTLNLVQAMGDVHLDVPLWCLTQGAVSISADLIRCSSAALVWGLGRVVALEHPGSWGGLVDLPESPDD---AAWERLCALLA
QPTDEDQFAIRPSGVFLRRLIHAPATTT-SKSSTAWAPRGTVLITGGTGALGAHVARWLAHKYEVDLLLTSRRGMAADGA------TELVDDLRTAGASV
TVHACDVTDRTSVEAAIAGK------SLDAVFHLAGRHQPTLLTELEDESFSDELAPKVHGAQVLSDITSN-TLSAFVMFSSVAGIWGGKSQGAYAAANA
FLDSLAEKRR-TLGLPATSVAWGLWAGGGMGDRP-SASGLNLIGLKSMSADLAVQALSDAIDRPQATTVASVNWDRFYPTF------------------A
LA----RPRPFLHEITEVM-AYRESMR----------SSSA---STATLLTSKLAGL----TATEQRAVTRKLVLDQAASVLGYESLDTHESFKDLGFDS
LTALELRDHLQTATGLNLSSTLIFDHPTPHAVAEHLLEQIPGIG------
>tr|S3ZQL1|S3ZQL1_9ACTN Putative Oleandomycin polyketide synthase, modules 5 and 6 OS=Streptomyces aurantiacus JA 4570 GN=STRAU_6263 PE=4 SV=1
SWRYRVAWQPLPAGRLPARLSGRWLVVVPD-SWVTGAAALTGAGAEAVRWGTE-ET-------------TRDGLAARLREAASGGSPLVGVVSLLGLDET
PLD-----EHTAVPAGLAATVALVQALGDIGSDARLWALTQGAVSTGRDRLDHPVQAHLWGLGRTVALEHPDRWGGLVDVPRSYDT---RAGARLAAILA
GPGTEDQLAVRGSGVFVRRLLRGEATGAGLTRHTRWTPRGTVLVTGGTGALGGHVARWLAREGAEHLVLTSRRGPDAPGA------AELRAELEEHGARV
TVAACDAADRQALARVLDGIP----APLTAVVHTAGILDDGVVDGLTPERFDGVLRPKSPAATTLHELTRD-DLDAFVLYSSASGALGSAGQANYAAANA
YLDALAEQRR-ADGLPATSIAWGTWDGAGLADTAVRSDRARRDGMPPMPPEPAVAALRDAVERGDAHVVAAVDWDTFLPGF------------------V
AA----RPNPLFDALPEVR-RRTADSA----------DGTPGATVTGPEWIRRLAPL----PPAERDAALVTFVRSQAAAVLGHDAVDPARAFRELGFDS
LTAVELRNRVQAATGLRLPASLVFDYPNSAVLAAHLAEEAFGAA------
>tr|S3ZNP4|S3ZNP4_9ACTN Putative Oleandomycin polyketide synthase, modules 5 and 6 OS=Streptomyces aurantiacus JA 4570 GN=STRAU_6973 PE=4 SV=1
SWRYRVTWKPLASGALPASLTGRWLVVVPE-DWLAGVTALTQAGAMVTEVSDA-EL-------------TREALTGRLRAYADAPGDPAGVVSLLALAEH
PHP-----SHPVLPTGLAATLALVQALGDTGIGARLWAVSCGAVSTGRDRLGGPEQAQLWGLGRVVALEHPDRWGGLVDLPPTPDN---RAATRLATALG
GTGFEDQVAVRGSGLFVRRLAHAPLDAR---PAPAWTPRGTALITGGTGALGAHVARWLAREGAEHLVLTSRRGLDAPGA------AELKAELAELGAEV
TIAACDVADRDAVAGLLDELAAH-GHRIRSVFHAAGVSPALALADTAPADLAEALDAKAAGAAHLDALLDD-ELDAFVLFSSIAAVWGSGGQAGYAAANA
FLDAVAERRR-ARGLTATSVAWGAWGGSGMAATAEAEEHLRRRGVALLAPDLAVGALAQALAHDETCTVADVDWERFAPTF------------------T
AA----RPSAFLGGLPELR-PQTRQAT----------AGAAEAR-RATASRSRSGPP----GSPGSRRRSG-----SASSSTSYRPRPSAPPAPSASWAS
TP----SPRWSCATASPPPPRSRCPRPW----------------------
>tr|A0A0C1QE45|A0A0C1QE45_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces pluripotens GN=LK07_27715 PE=4 SV=1
GWRYSVGWRPAEA-AE-PTLSGDWLVVSPD-G-AEDCAVLTRAGAEARVL-------------------GPDALPAALAGA-----AVRGVVSLLGLAEG
PHP-----EQPAVPAAVAATLELVRALADTDTGAVLWLVTTGAVATTPDWLPHPEQAMLWGLGRTLALEHPKLFGGIVDLPQDPTL---G-LDRLPAL--
LAGTEDQVAVRATGVLVPRLAHAPLRGR--TPARRWQPTGTVLVTDGLGPMGLPAARWLAGNGAQALVLTTDDPA--------------ATAPDDLGVPV
TLSTCDPADETALAELLAGIPAD---PLTAVVHAAGTLRSGPLAGTDLSEVAATIDTKVRGAANLDRLT---ELDAFVLFSSIAGTWGGSEQGAFAAANA
YLDALAQHRH-ARGLPATAIAWGPWQGAGLGDTERRREQLRRRGVLALAPQQALAAMADAVRHADTTTVADVDWAVFAPAF------------------T
AA----RPSPLLGELPEVR-DSLAEVT----------DEPA---G--SGTATRLGSL----PEADQQRELIELVRREVAAVLGHETLPTGRPFTDLGFDS
LAAVNLRNRLGAATGVRLAATAVFDHPTPAGLADHLRRQLVVPA------
>tr|A0A0C1SIQ3|A0A0C1SIQ3_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. RSD-27 GN=PL81_26115 PE=4 SV=1
GWRYRVIWKPQADAA-SPRLSGSWLVAVPE-A-AAGVLTLADRGAEVRTVAPD-AA-------------GRDALTAALKAATGA--APAGVLSLLALGD-
-------------DGAFAAGLALSQALGDAEVAAPLWCVTRGAVVAGRDRIADPEQALIWGLGRVASMEQGGRWGGLIDLPGPVDD---RALERLAGVLA
GDAAEDQVAVRSSGLFVRRLVRAGLSET--PAVREWRPAGTTLVTGGTGALGAHVARWLASSGAEHLILTSRRGADAPGA------AELRDELTALGAEV
TIAACDVSDRDALAALLAAIPAD---PLTAVIHAAAVVDDGVIEALTPEQVERVLRVKVDATRHLHELTRD-DLSAFVLFSSFAATFGAPGQGNQAPGNA
FLDAFAEYRR-AAGLPATSLAWGPWGSGDGDGS-AAGDRMRRHGIIAMAPERTLASLRHALDRDETTTLVDMDWKRFTLAF------------------T
AD----RPRPLLLELPEAR-RVIESAE----------REST-DLAGGVPLSTQLAGL----PDVEQERLLLDLVRTAVAAVLGHTAVEAGRAFKELGFDS
LTSVELRNRLGAVSGLKLPASLVFDHPTPAAVAAYLRAGIVPDA------
>tr|A0A099D0D6|A0A099D0D6_9ACTN Uncharacterized protein (Fragment) OS=Actinopolyspora erythraea GN=IL38_24395 PE=4 SV=1
NWRYQVVWRDSEWQS--TSLAGRVLLVTGPG-LSNSVRGLEQSGATVLVC-----E-------------SRHVIGAALEEAD----ALSTVVALLGGEGE
TV------------DASLDALALVRALGVAGIEAPLWVLTRNAVQVTD--EVDPAQAMVGGLGRVVGVEQPSRWGGLVDLIDV-DA---ASVRALAAVLA
DPRGEEQIAIRPDGIKVARFVPAPARAA----RTRWSPRGTVLVTGGTGGIGAHVARWLARSGAEHLVLLGRRGADAPGA------AELRDELIALGTGV
TIAACDVADRERLEEVLAAERAE-G-SVNAVLHAAGISRAAPVEEITETEFAEVAEAKVRGTVNLDELCP--DLDAFVLFSSNAGVWGSPGLACYAAANA
FLDGFARRRR-SEGARVSAIAWGLWAGQNMAGD-EGGEYLRGQGLRAMEPERAIEELHVTLDHGQASSVVDMDRERFVELF------------------T
AA----RRRPLFDEITGAR-GEARQS------------------EEDPKLEQRLAAL----SEFERREHVARLVHTEVAAVLGHTMIDRDRAFRDLGFDS
MTAVDLRNRLAAVTGVREAATVVFDHPNITRLAEHYLEQLVGGA------
>tr|D9WB06|D9WB06_9ACTN Oleandomycin polyketide synthase, modules 5 and 6 OS=Streptomyces himastatinicus ATCC 53653 GN=SSOG_00512 PE=4 SV=1
AWCYRADWTRLREP--ATPLTGRWLAVVPA-EWA-A--VLDALGPDVVRISTE-DT-------------DREQLAARLAHAGNS--EFTGVLSLLGLAER
PHS-----GFTSVPSGLSATLALVQALGDARLRAPLWCVTRGAVSAARDRVSHPVQGALWGFGRVVALEQPGLWGGLVDLPETLDQ---RAAARLAGVLA
GLDGEDQVAVRASGAFGRRLFHAEPASA--RPERPWRTRGTVLITGGTGGLGPYLARWAIERGAGHVVLAGRRGPDAPGA------TALRAELEGLGARV
TVVACDAADRDALSAVLSAIPAE-FPPLSAVIHAAGVTDGDEAASLTPDRLDALMRPKLTAALNLHELTTD-RLDAFVLFSSGASAWGSGGQPGYAAGNA
YLDALAEHRR-ARGLTATSIAWGAWGEAGMATDPHLVERLAKRGVLPMEPPKAIAALQRVLDDDRTTTVSAMDWAAFAPSF------------------T
VS----RRSPLLSGLPEAR-EPAPADT----------AGEADTADGTPSLPHRLAEL----PDAERRRVLLDAVRAEVAAALGHDAVPADRAFRDLGFDS
VSAVELRNRLKAVTGLPLPAALVFDHPNPTALAGHIGAELFPGT------
>tr|A0A0F5A528|A0A0F5A528_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. MUSC164 GN=VT50_29325 PE=4 SV=1
SWRHRVVWKQLPDSA-TPTLSGTWLLLVPS-GAVHATIALDAHGAAHEVLDGT-DA-------------RPDALAPKLSQLSLPDGTPEGILSLLALDQA
PHP-----EHPAVPVGLAATAAVVQALSRTALTAPLWCVTQGAVAATADPLPHPHQAQIWGMGRVAALEHPHLWGGLIDLPADVDA---RTPARIAAVLA
PGQPEDQVAIR-ATPLARRLERATCQDT---APTAWRPTGTTLITGGTGGLGAHVARWLARRGAPHIHLISRSGPDAPGA------AQLTEDLTALGAAV
TISACDVADRAALQHLLDTVPAE---PLTAVVHAAGLAENTPLAELDLPGIEAVLRPKALAATHLHELTEH-DLSAFVLFSSGAAAWGGSRQPSYAAANA
YLDALAEHRR-ARGLPATSIAWAPWSDAGMAADEAVVDYYRRRGMRPLDTDLAIASLQHALDHGDTTTIADIDWERFPAGF------------------T
AQ----RPSPLLSDLAASA-SPGTDAT----------P---DDAALSSSLQRQLATG----TPAQQHQLLLHHIQTHAAAILGHDAIPPAQPFQELGFDS
LTAVEFGHRLSSATGLGLPPTLVFDHPTPKELADYLRERLVEGQ------
>tr|A0A014MJ18|A0A014MJ18_9ACTN Beta-ketoacyl synthase (Fragment) OS=Streptomyces sp. PRh5 GN=Z951_46685 PE=4 SV=1
RWRHRIDWSPLPEPPA-VAEPGRWLVLGAT--WTDSVVALGDQAVH----VSA-EA-------------PRAELAERLRAQP----PADGVLLT------
-------------PGTPVDAAAMLQALDDAGLATPTWIATRAAVAVGSDPQPWADQAGVWGLGRVAAWEYPAHWGGLVDLPEDVDE---AVAARLRSLLT
EEKAENQVAIRSTGLYGRRLVRAAPEA----PTRAWTPEGTVLITGGTGGLGAELARWAAGRGADHLILLSRRGPDAPGA------GELREACEQAGARV
TFVAADVADRARMAAVFDE-------PVTSVFHLAASLDDGVLDTLTPDGFATVARAKVRGAQVLDELTRG-GLSAFVLFSSISGVFGVPGLGAYAAANA
MLDALAVSRR-AAGEQALAVAWGAWAGEGLATHVVGDERLRRMGLTAMPAKAALVALEHALNREDTTAVFDADWDRV-PAH------------------T
RD----GLGTLLHELPEAR-RPAAVSR----------P-------DAADLRTLLAGL----DAAQRTAKLRDLVHAEVADALGHVAVDPRRAFSELGFDS
LTSVRLRNRLTELTGLSMPVTVVFDFPTVTELGEHLAGRLGGAG------
>tr|A0A0M3U7J4|A0A0M3U7J4_9PSEU Polyketide synthase OS=Pseudonocardia sp. AL041005-10 GN=WY02_28940 PE=4 SV=1
GSLYRLEWRRSTSPPVP--PAGPVAVLGDP-ARVHRLTLLRPAPAVLVTVHSS-GT-------------DSAPIR-------------------------
------------AERCISRTLGQLQAHG--PAQSRLVVATRAAQ-PGPDHEVDPAAAAVWGLVRSAQTENPGRFA-LVDLDDD--P---ASWELLARAA-
-TDTRHQFRIRNGVVETPRLVPVAEPVP--TASPALDLAGTVLVTGGTSGLGAVLARHLVARHDRSLLLVSRRGPDAPGA------AALTAQLRAAGADV
TVAACDVADRMAVADVLAEVPAD---PLCAVVHCAAALEDGVVESLDPARIRAALAAKGVGAWNLQALTES-DLAAFVLFSSVAGTLGTAGQAAYAAANA
FLDGLAAGRH-ARGRPATSLCWGYWAEDLSALRDSDLDRLRRQGVGALDTQRGLALFDAALHRPEPVLAARLH----PPAP------------------T
DD----RLASLLTTLSAPP-ARTDPPG----------PDEYTATSRGDSPAERLAGL----TESEAEARLLKIVRHHTAVVLGHAALAPSSSFKELGIDS
LTALEVRNGLAHALGTALPATLVFDHPTPAAVSRHLLRTLGPSS------
>tr|A0A0A0NVE6|A0A0A0NVE6_9ACTN Uncharacterized protein OS=Streptomyces rapamycinicus NRRL 5491 GN=M271_46365 PE=4 SV=1
AWRYRIDWSPVSEAA-AASLTGTWLVAVDA-GWVADCAALAMHGALPVVVA-A-DA-------------DREAVAARL------REEVTGVLSLLALAE-
--S-----RYAAVPSGLALTLSLLQGIGDAGVGGRVWCVTRGAMATRGESPLSLEQAAVWGLGRVAGMEAPERWGGLVDLPQDPDG---RALQRLTAVI-
GATGEDEVAVRASGVFARRVVRAAVGAE---NGETWQPSGTVLVTGGTGALGVHVARWLARAGAEHLVLVSRRGPAAEGV------DKLRAQLAELGARV
TVAACDVGDREALAGVLARVP----EPLTAVVHTAGVLDDGVLDGLSVDRFQGVLRAKSEAAWHLHELTRE-DLSAFVLFSSFSATVGGAGQGNYAAANA
FLDALAEHRR-AEGLPATSVAWGPWADGGMATQDAISGRMERFGLPAMEPELAVTAMARAVNQPDSCVITDIDWPRFTAGV------------------D
GT----RLGLLFGDIAEVR-TARQAAD----------A---QAGPHRPTLATTLAEL----PAAEREPALRDLVRTHTAAVLGYEGIDTERGFFDMGLDS
LTAVELRNRLNAATGLRLRPTALFDYGSPSALARHLKGELVEDE------
>tr|V6L2I9|V6L2I9_9ACTN Uncharacterized protein (Fragment) OS=Streptomycetaceae bacterium MP113-05 GN=N566_10455 PE=4 SV=1
GWRYRTEWKSVHPA--GEPLAGTWLLVRAD-GALDETAALSDGGADLVEVA----G-------------DVADLGTRLSEALD---TPTGALCLTAFDEA
PLS-----TGGPVPTGLALLTATAAALEALGTDAPLWAATVQAVGTGPDPPCNPAQALVWGAGVVLGLDLPRTWGGLIDLPATLGP---TGAEQLRVALI
GATGEEQLALRPDGLTARRLVRAPADAG----TAPWRPRDTVLITGGTGALGGHLARWAARSGASRVVLVSRRGEAAAGM------PELRDELFDLGTEA
VIAACDLTERDAVAALIEKITVD-GPPLRAVLHAAGTSGREAVADLTTDDMATVLGPKAAGARHLADLVDDEKLDTFLLFSSGAGIWGNAGRVAYGAANA
YLDALAAARS-ASGRPTTSLAWGPWGGGGMVDA-DTGRYLQRLGMRQMDPEQAVQALADSVGRGEGEVVADIDWKTFAPTY------------------T
AA----RNRPLITGVADAR-DALTAAD----------DTPG-TEDGEPELVRELGGL----DAAERQRQLLDRLRREAAVALGHAEMRADR---------
--------------------------------------------------
>tr|D9WB07|D9WB07_9ACTN Modular polyketide synthase (Fragment) OS=Streptomyces himastatinicus ATCC 53653 GN=SSOG_00513 PE=4 SV=1
SWRHREVWRRRSFPA--GKASGTWLVVTPP-GWISTVAALGPDTVRIEAR--G-DA-------------GRAALAERLTTAT-GLPSVAGVLSLLAADES
A-------DDAGVPAGLVRTAALVQALGDAGLHCPLWCVTRGAVAVNDEHPSGPAQAAVWGLGRVAALEYPDRWGGLIDLPTELNE---PSAAAFVAVLA
GRDGEDQVAVRPSGTYVRRLVPAPAP----RPAAEWEPSGTVLITGGTGALGAHVARALARRGPPHLLLVSRSGPAASGA------ADLRRELTELGADV
TIAACDAADRAGLEAVLADIPA--DRPLTGVVHAAGVLDDGVLDRLTPDRFAAVFRAKVASALLLDELTRDADLSAFVLFSSVSSVVGNPGQANYAAANA
SLDALAQRRH-ARGLPATSIAWGGWGGAGMAARP--SGASGGVALARLDPRLAVSALSEAVTEPHPTVVADLSHLASQDPP------------------S
GL----RRTPLLEELPYAR-RAPRE---------------------GSAPAPRLRDL----PEAERAARALETVRERAAAVLGHNLVHADKAFRDSGFTS
LTAVELRNHLAAETGLALPTGVVFDYPTPRLLAEHLVAGLGGER------
>tr|J1ZM11|J1ZM11_9ACTN Acyl transferase OS=Streptomyces auratus AGR0001 GN=SU9_33783 PE=4 SV=1
GWRYRVAWDRLPTDA-PVALDGTWWIVVPG-DTADAVRALAAAGANPRILDPH-GT-------------DRAALAKELEERAAD--TVAGTVSLLAESGG
EDT-----GHRGVAAGALATLVLLQALHDADIPTRLWTLTRGAVRSGPDTAPDPWQAQVWGLGRVAALEHPALWGGLIDLPAEGE------PAGLAAVLS
GTAGEDQVALRGDGARARRLTPADTHDAPASGAYRW-TDGAVLITGGTGALGAHTARMLASRGASRLVLVSRRGPAAPGA------EALRAELEAFGATV
DLTACDVTDRDAVGRLAEGLAAA-GTPVRAVVHAAGVAAEQPLTDLVGGDFSAVTDAKVTAAEILDDVLGD-DLAAFVVYSSIAGTWGSAGNGPYAAANA
HLDALVERRR-ARGAAGTAVAWGPWSGGGMADD-RFQEEMLRRGVRALSPEGATAALAQALEHDDTTTVVDVDWDRFAHVF------------------A
SN----RPSPLLGHLTEPA-AAADEA------------------PARTEPAERLAAL----DAEARRGAVLDLVRAEVAGVLGHQAVAVDRAFTDMGFDS
LMAVELRTRLGVVSGLALPTTLVFDHPSPAEVADFLCARFEPDR------
>tr|A0A0D8B5G3|A0A0D8B5G3_9ACTN Acyltransferase family protein,phosphopantetheine-containing protein OS=Frankia sp. CpI1-S GN=FF36_06391 PE=4 SV=1
SWRYRIAWRPVPQSASAPASDGDWLLVVAP-ERVAAAVALEDAGAAVRRLVPA-AA-------------DRRTLATELTRLLAPIGAVAGVLSLLALDES
AHP-----DAAATPLGLAGTVALLQALDDTGLDARLWIATSGAVSTSADPVTRPADALLWGLGAICAVEYPGRWGGIVDLPDQVDE---EAARLLATALR
AGHGEAELVVRSGGLLARRLVPAPTEARPPGSVADWAAEGTVLITGGTGALGGHVARWLAREGAAHLLLTSRRGERAPGA------GELAEELRALGARV
TIAAVDVGDRDALAEVIGGIPAE---PLRAVVHTAAVLDDGLVSELTLEQIDRVLRVKVGGALNLHELTRD-DLAAFVLFSSIAGTAGITGQGNYAPGNA
YLDAFAAYRR-AAGLVATSIAWGQWDGAGLAEP-DVERILGRYGLLAMDPQPAVRALAGALASDETHAIVAADWPVF----------------------Y
RS----RPHPLVHELPEVA-AERSALA----------ERSGAGDGDGPVLAARLAEL----DGPARREALLAIVRDHVAAVQGHDAVDVDRGFRDQGFDS
LAAVNLRNRLIAETGLSLPVSLVFDYPTAAALTDHLLGELVPDE------
>tr|A0A0F2SS02|A0A0F2SS02_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces rubellomurinus subsp. indigoferus GN=VM98_28580 PE=4 SV=1
GWRYRVEWRRRADPD-RPAPQGRWLLLAPP-GRA-----------DVER-EVA-AA-------------DRESLARLLRDTA----GVAGVVSLLPA---
-----------------VGVLVLLQALEDSGVDARLWCVTRGAVSVGADRVTSPEQARTWGLGRVAALELPHRWGGLVDLPDG-------GAVDLAAVLT
ADEGEDQLAVRPTGTYVRRLVRAPLADP-EGGIAPWTPSGTVLVT-GTGSVAARVARWLLDRGAEHVALTGPVGG----P------DADRADLSDLGGRI
SCSGREADDLAGTAALVQRLAEQ-GRPVRAVVHTAAGTTLAPLLRATPADLAATVAATVTPAVHALDLLP--DLTAAVLFTSVSGVWGTGEHAAFAAANA
QLDALAEQRR-AAGAPVVSVAWGVWNTLTPGEAADALARPARHGVPLLDPDRALAALDEITARGERGVIAEVDWARFAPLF------------------G
SA----RPTRLFAELPEAS-TAAPPQA----------VT--GDAERAADLRRRLAAA----AGPERDRLLLELVRGHAAAALGHGAVAAERPFRELGFDS
LIAVRLRNGLSAATGVPLPLTLVFDHPTPAALAAHLGERLGGGE------
>tr|A0A0M2GG63|A0A0M2GG63_9ACTN Polyketide synthase (Fragment) OS=Streptomyces variegatus GN=UK15_38905 PE=4 SV=1
SWRYRIAWQPLADGP-EPVLSGTWLAVLPQ-GWAAGCLSLTVRGARTLPIGTA-DG-------------ERAPLAERIASAVETDGPVAGVVSLLALADA
PHA-----QQPAVSQGLAATLALVQALGDAEVAAPLWCLTTGAVSTSPDRPAHPGQAQIWGLGRVIALEHPDRWGGLVDLPETPDE---RSLTRLTAALS
DPAFEDQLAVRASGTAVRRLTRAPRET---ADATPWQPHGTVLVTGGTGALGAEVARWLARDGAGHLLLTSRRGPAADGA------AELRDELIALGADV
TIAACDAADRTALAALLAAVPA--EQPLTAVVHAAGVLDDGVLDGQTPERFARVLRPKADAARNLHELTADHDLAAFVLFSSVAGTLGNAGQANYAAANA
YLDALAEQRR-ADGLPATTIAWGPWAGAGMAAAEPDGDRLRRIGLAPMDRDTAVEALRRTVEGGAAVAVADIDWARFAEVF------------------A
AQ----RPSALLSDLPEAR-GHLAGSG----------GQVTD----AAEWRLRIAAL----PENEREPALLELVREQVALVLGHAAVPADKAFKDTGFDS
LAAVQLRNRLGQVTGLRLPATLVFDHPTPTALARFLTAESAGST------
>tr|A0A0M2GBT8|A0A0M2GBT8_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces variegatus GN=UK15_38940 PE=4 SV=1
SWRYRITWKPLAEAA-PTVPAGTWLAVVPE-AWVDATLAMDGRGARTVVLGSA-EG-------------DRAALARRLTELV-EEGSVAGVLSFLALDET
ARP-----QHPGVTAGLWSTLELVRALGDADATAPLWCLTRGAVSVGRDRLASPAQAQAWGLGRVVGLEHPDRWGGLVDVPETADE---PALRRLLAVLA
GSGDEDQIAVRASGVFVRRLAHAPRRT---ADGAPWRPRGTVLVTGGTGALGAEVARWLARNGAEHLILTSRRGIEAPGA------GELRRELAGFGAEV
TVAACDVADREALADLLAALPP--ERPLRAVVHAAGVGQYAPLAGMDADEFARVVTGKVAGARHLHELLLDTPLDAFVLFSSVSGIWGSGGQGAYAAANA
YLDALAQQRR-DSGRPATALAWGPWAEVGLAAADTGEAQLRRGGLLPLAPESAIAALQQAMDADDTATIADVMWEQFLPGF------------------A
VA----RPRPLIGDLPAVR-KVLDAER----------PHDTG---ADSALARRLRGL----SEADRGRALLELVRSETAAVLGHDDVAAERPFKELGFDS
LTAVEFRNRLNSATGLTLPSTLVYDFPTAAVLAERLGRELRGAG------
>tr|H0KA26|H0KA26_9PSEU Beta-ketoacyl synthase OS=Saccharomonospora azurea SZMC 14600 GN=SZMC14600_19884 PE=4 SV=1
DARYRVTWQPVPDNP-AATVTGRWLLLAPE-DLT------TAFGDRVDVR--D-TP-------------DRAMFADLP--------DYEGVAIVV-----
----------SAGDRGARESLLAAQALGDRGIDAPLWLLTRGAVSAGRDRPTDPVQAQVWGLGRVVGLEHPERWGGVLDLPDVVDE---QAAARVLGVL-
AGGRETEVAVRPDGVYARRLVSSPQRA----GTDSWSPTGTVLVTGGTGALGGEVARWAAREGAKRLVLTSRRGAEAPGA------SELADELREFGVDV
TLAACDLADRDAVAALVKDCG-----DLTAVVHAAGVSQSTPLADTTPEEFAAVIAGKVAGAMHLHELTA--DLDAFVVFSSIAGVWGSAGQVAYSAANA
ALDALVEQRR-ADGLPGTAVAWGPWAGGGMAGGD--GAQLARMGLSGLAPEQAIAALARAVGSGDVTTVADVDWSRFLPIF------------------T
AT----GSTPLFTALAEVD-AD--------------------ADQEVTDRRAELAAL----APADRQRTVLDLVRAEAAIVLGLNAVEPARPFRDLGMDS
VTSVELRDRLATVSGVRLPATAVFDHPTPDDLVAHLIAEITGDD------
>tr|A0A0A0NLN1|A0A0A0NLN1_9ACTN Uncharacterized protein OS=Streptomyces rapamycinicus NRRL 5491 GN=M271_45455 PE=4 SV=1
RLRYQVTWKPLPGATS-GVPTGTWLVVLPY-GYAAQVAALNRQGLRTTTLGPEPP--------------DRAAFAGMLRGALDH--DIGGVLSLLALDQR
VRS-----GSATLTEGSAATLALVQALGDLGSGHRLYCATQGAVTVGADRLSAPEQAAVWGLGLAVALEQPDRWGALVDLPDVFDD---RAARTLLAALA
GPGDEDQLAIRATGAFVRRLRSHPLTTG-A-TKPEWRPRGTVLVTGGTEGLGRHAARWLAGAGAEHLVLTVGSDPEAPHV------VALRDELSGLGAKV
TVCPTDLTDRDAVERLLTGPAAY---ELSGVVHTADLARIAQTDATSTDELAETLAAKVDGLLHLDTLLAD-ELDLFVVFSSVAGVWGGGGQGLIGAANA
QLDALIERRR-ARGLVATSVAWGVIDGFGVAADATAQEQLRRRGVLPMAPEAAMAALTHAVRHDDTLAVVDIDWSAFVPAF------------------T
SL----RPSPLIGDLPGVQ-EIVDSLR----------TDDT--DGSASEFLRELAAG----SDAERERALMKAVRENAAVALGHEAVKPQRAFQEMGFDS
LAAVNLRNTLGAALGTRLPATLVFDYPTPAALVEYLRAELLGDQ------
>tr|A0A0F5A369|A0A0F5A369_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. MUSC164 GN=VT50_33550 PE=4 SV=1
GWRYRVTWKPVTDRS-AASLTGCWLVVAPA-GWAAGAVMLNERGVDVRRV--A-DD-------------DRAAVAERL------AAVTGGVLSLLALAD-
--E-----GDG-DGDVLLRTAALTQALGDAGIGAPLWVATRGAVAVGRDGTVSPAQARLWGLGRVAALEVPERWGGLVDLPETADE---RALGRLAEVLA
GGGGEDQVAVRASGVFGRRLVRASVSAS---ASDSWTPGGTTLVTGGTGALGAQVARWLVENGAAHVLLTSRRGLDAPGA------AELRDELAASGARV
TVAGCDVADRDALARLLADIP----APLTAVVHTAGVLDDGVLDSLTPERFATVLRAKADAALALDELTRD-ELSAFVLFSSISGTFGAAGQGNYAAANA
YLDALAERRR-AQGLPATSIAWGPWAEGGMATDGALEQRLRRGGLPPMDAELATGALQRALDLDDTVTVADIDWERFAPDF------------------T
AA----RPSRLLADLPELR-AAAENTA----------T----PAADGSSLAARLAGL----AEAERDRLLLDLVRTQVAAVLGHESIGADRAFGELGFDS
LTAVELRNRLGAASGVQLPATLVFDYPTAAALAGYLRGELIETG------
>tr|A0A0A0N8P6|A0A0A0N8P6_9ACTN Uncharacterized protein OS=Streptomyces rapamycinicus NRRL 5491 GN=M271_09695 PE=4 SV=1
SGVRPVAVYSRPED--QVRLPGERVGE--VEAWSSVVRRLTRAGSDAVALDAAGQPVISI-----ESLALRPISAEQLQAAQ--SRPETVVLSCPA--GG
GED-----LVAGVGESLSAVLSSVQGEDRL-FGSRLVVVTCGAVATEMEDVADLVQAPVWGLLRSVQTENPGRFLLLDHDPDHHDP---DADAVVRAIA-
-TGEESQLAVRGETVLVPRLSRVAKPAADLGTSTRLVSGGTVLVTGASGVLAGVMARHLVADHGEHLLLASRRGPDAPGA------AELVAELEAAGASV
TVAACDVADREEVRELLAAIPGQ---PLRGVVHTAAVVDDGVVEGLTDERVQRVLAPKVDAAWHLHELTQD-GLEAFVLYSSVASTLGAGGQGSYAAANA
FLDALAQRRH-AHGLPAVSLAWGLWA-SGITSQ-TDIARMARGGTTGLTTEEGLVLFDTAQSVGRPHMPVRMDLTSHQAH-------------------P
EV----PVPAMLRNLIRTP-LRKAATG----------QS------GAKQWRDRLLGA----SPEERERLLLDLVRISTATVLGHGDIDLEGEFLEMGLDS
LTAVELRNQLGGATGLRLSTTMVFDHPTPADLAVHLADELNTLA------
>tr|A0A0A0N9L0|A0A0A0N9L0_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces rapamycinicus NRRL 5491 GN=M271_09710 PE=4 SV=1
AGLRPVAVYSHLED--VVRLPQECVAE--AEAWSSVVRRLTRAGSDAVSLDAAGQPVVSV-----ESLVLRSISAEQLQAAQ--SRPETVVLSCPM--SG
D-D-----VVVGVGESLSAVLSSVQGEERL-FGSRLVVATCGAVATETEDVADLVQAPVWGLLRSVQTENPGRFLLLDHDPEH-------ADAVVRVLV-
-AGEEPQLAVRGGTVLVPRLSRVAKPAVDLEASVPLVSGGTVLVTGASGVLAGVVARHLVVGRGEHLLLASRRGSDAPGM------AELVAELEAAGASV
TVAACDVADREAVRELLAGISAE---PLRGVVHTAGVVDDGVVGGLSDERVRRVLAPKVDAAWHLHELTRD-GLEAFVLYSSAAATLGAGGQGSYAAANA
FLDALAQHRH-AHGLPALSLGWGLWA-SGITSE-TDLARMARGGTTGLTTEEGLALFDVAQGVGRGVLPVRVDVRAFRGR-------------------G
GV----LVPALLRNVVRGA-VRRVAVG----------RD------GSGAWRDRLAGV----ASGERERLLLELVRSHVATVLGHAGIDADRALKDLGFDS
LTAIELRNQVGAATELRLPTTLIFDYPTPSAIARYLDGRLGAGV------
>tr|S3ZC23|S3ZC23_9ACTN Putative Phenolphthiocerol synthesis polyketide synthase type I Pks15/1 OS=Streptomyces aurantiacus JA 4570 GN=STRAU_5687 PE=4 
SGHRPISLHSRPEP--GVALPDDDHTQ--AGAWTATVRRLTPNGTDGVSLDATGAPVASV-----DALVFRPMSKELIERMSPNPHPAAVVWSAERSARA
D-A-----RPESVSASLAEALAVVQADERF-AASRLVVVTRGAVVIGTAASPDPVAAAVAGLVRSAQTEHPGRFVLVDADVSG-------TESGLAEVL-
-ASGEPEVAVRDGAVWVPRLSRVAAAEP--GVVEAPWGSGTVLVTGAFGGLGRVVVRHLAERHGRDLLLVSRRGLEAAGA------AELQAELAQLGTTA
TIAACDVADRDALAALLEESGE----GLSAVVHVAGVLDDGVVTALTPERLARVLRPKVDAALNLHELTSG-DLSAFVLFSSASGVFGGPGQANYAAANA
YLDALAAVRR-TQGLPATSLAWGLWAASDMTAD-ADLQRMARGGVLALDTERALTLLDLAPASEHPAVPIRIDTAALRNQ-------------------P
PE----ALPALLSGLVRPA-VRRAQTG----------T---DPAARTESLAQRLAGR----TGAERDRMLLDLVRTHVAGVLGYNAVELSRGFLELGFDS
LTAVELRNRLTAETELRLPSTLIFDYPNPAALAEHLSEELPTTA------
>tr|A0A0N0T538|A0A0N0T538_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. NRRL WC-3618 GN=ADL01_17410 PE=4 SV=1
NGRSAVSVHSRDEG--DVALPEEEAAD--AAGWSATVRRLSSAGADTVTLDETGQVVATV-----DSLVSRSVSDDRLG---GGTFPATVVWPVDRPSPV
DRV-----RPEDVSAFLAEALGVVQADERF-EGARLVVVTRGAAPVEGGADLDPAGAALWGLVRSAQVENPGRFLLVDTEMAPLGT---GDAPALAAAL-
-AAGEPEVVVRAGAVWVPRLTRPTTRVSADETAASPYGEGTVLVTGAFGGLGRVVARHLAEHHRRDLLLVSRRGDAAAGA------DELRAELEAVGAKV
TVAACDVADRDALAALLDEAGG----ELSAVVHAAGVLDDGIVTSLTPERLDTVLRPKAAAALHLHELTAG-DLSAFVLFSSAAGVLGSAGQANYAAANG
LLDALAGIRR-AQGLPATSLAWGLWA-SDMTDG-TDLGRMARGGVAALSTDEGLALLDIAVTDAPATVPLRLDTASLRAAA------------------G
PD----GVQPVFSELVRTP-ARRVDRA----------QARSNADPGTPALVKELAEL----SGADRERALLDAVRGNVATVLGHEAVGATRGFLELGVDS
LTAVELRNRLNSLFGLRLPATLIFDYPSPTALASYLDESLPQAG------
>tr|W7VQN7|W7VQN7_9ACTN Type I polyketide synthase OS=Micromonospora sp. M42 GN=MCBG_06093 PE=4 SV=1
AWSYRVGWKRADITAGPPARPGAWLLVTAQDDRAEAVTALAEVGADVVRLDPA-GT-------------DRAGLARRLGDA-LADGPVTGVLSLLGLRDQ
PHP-----AHPAVPVGTAATLLLLQALHDTGATTRLWCLTQGAVSTGDDTVHAVIQSGLWGLGLVAGLEHPHLWGGLVDLPEQADA---TAWDRLARVVT
GAGDEDQLAVRPSGVFVRRLVRSAPAAP--DTAQRWRPSGTVLVTGGTGALGAHVARWAAANGAEHVVLTSRRGGDAPGA------VELREELIAQSVRA
SVVACDVAERDQVAALLARLDED-PAPLTAVVHAAGAGESGLIADTDLAAFAGVLDGKVAGALHLDALLGDRPLDAFVLFSSIAGVWGSGGQSAYAAGNA
FLDALAEQRR-GRGLAATSVAWGPWADGGMATGE-AQQMLARRGLTAMAPADAVHAMRYAAGLPRAATVVDVDWAVFAPAY------------------A
SA----RPRPLLDDIAEAR-EALHAHA----------VEQ--PGGAADALREHLLTL----PRPERVRHLVDLVRTHASAVLGHDRVKPQRAFKELGFDS
LTAVELRNRLTGVTGLSLPATLVFDYPNPAVLAENLLDGLLPEA------
>tr|A0A059WKJ2|A0A059WKJ2_STRA9 Modular polyketide synthase OS=Streptomyces albulus GN=DC74_7916 PE=4 SV=1
TGRRALSVHARPDD--AIELPEPGPA---ERPWRTALRRLTPNGPDTWTLDPQGAPVLSV-----TGLILGTPTVEQSEAGT--EGPPPLVLAPLLGAPP
GDD-----LPAAVRTTTTAVLELLQADART-ADARLVIVTRGAVAA-GEDVADLAAAPVWGLVRSAQSEHPGSFLLLDLDPADALR---APD-ALTALL-
-DAGETQVAVRGGALTVARLTRAVDGPDAPHPVRAWDRDGTVLLTGGTGGLAGVLARHLVTGHGKHLLLAGRRGPDAPGA------TALRDELAGLGAEV
TVAACDASDRTALDALLAQLPPE---PLTAVVHTAGVLDDATVGALTPQRLDRVLRAKADAAWHLHQATRG-DLAGFVLYSSVAGVTGGPGQGNYAAANA
FLDALAAHRA-ARGLPGLSLAWGPWG-AGMTGA-ADLARLERSGMPPLTPAQGLALFDAAGARGAGLVATRLAQG-PAAP-------------------G
DG----QVPALLRALVRGR-RRTAAAA----------GH------GRGP-ARRLAAL----DPAQRERALLDLVRTETAAVLGHDAVPAERDFNRLGFDS
LMAVELRTRLAAATGTRLPAALVFDHPTPLAVARHLHSTLPGAA------
>tr|G2NZK8|G2NZK8_STRVO Beta-ketoacyl synthase OS=Streptomyces violaceusniger Tu 4113 GN=Strvi_3972 PE=4 SV=1
SWRYRATWQQLPDPAT-PALTGTWLVVAPAGQEHATVQALRAHGATALPLAVDAHDI------------DRAALRERLGRLPE-EAQPAGVISLLALDQE
PLAGH-----SAVPAGLGATVALLQALGDADISAPLWCVTQGAVATGRSLLPHPEQSQIWGFGRVAALEHPQRWGGLIDLPTTMTH---HTAGRLAALLV
AGQPEDQAAIRTTGTYARRLIRVPAGDT---APAPWEPSGSTLVTGGTGGLGAQLARWLAHRGAPHLHLISRSGPDAPGA------SELSEELTALGTDV
TITTCDASDRDALRQLIDTV-PA-EHPLTAVFHTAGTMELGQISELDPGRLQSVLRSKTLAAAHLHDLTQHLDLTAFVLFSSNAATWGSGHQAAYAAANT
YLDALADHRH-TRGLPATSLAWGPWGEAGMAADQHTLSHLKRRGLSPLPTDLAIASLHHALTHHDTAVIADVDWARFGGTFTAQ----------------
------RPSPFLAHLMPS------------A----AEAATPTDTADDNPLRQRLSAA----PAAQRHQILVRHIQSLAATILGHDAIPPAQPFQELGFDS
LTAVELRNQLAATTGLPLAPALVFDHPTPNALATYLGAELTG--------
>tr|X0N9F9|X0N9F9_STRA9 Beta-ketoacyl synthase (Fragment) OS=Streptomyces albulus PD-1 GN=P354_18905 PE=4 SV=1
GWSYRAGWTPVTART----TTGNWLVALPDSVT--LLDALRAQGLHT----------------------E--VL-DPSEP--LADGPIDGVLSLLAL-DR
PHPDL-----TSVPRGL--TTALLRAVEGSGKPVPLWCATRGAVAVDDRVLTNPLQAQLWGFGRVAALEYPRIWGGLVDLPETPDA---RAVSGLLDVLA
-G-AEDQVAIRAAGTFARRLARIAPGGT----GAGWTAHGTVLITGGTGALGAELARWFADAGAEHLVLTSRRGLEAPGA------PELAAELTDRGTPV
TIVACDAADRDALAAVLAIP-A--ETPLTGVVHAAGVMDAGMLDALTLERFEAVLRPKATAALNLHELTRELDLELFVLFSSIAGSLGNAGQANYSAANT
FLDALAEHRR-AQGLPATATAWGAWADRGMAT-Q-VADRVSRDGLIPMAPASALAALRQALAQGLTNVVADVDWTAYAPALTAV----------------
------RPSPLLADLPEA------------RRVAA--PE--SARADASPLGGRLGAL----SADERERVVLQTVQEEAAKTLGLDGIEARRAFRDVGFDS
LMSVELRNRLATVTGLALPTTLLFDHPTPSAVTAYLLAEILG--------
>tr|A0A0F4K578|A0A0F4K578_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. NRRL B-1568 GN=VR41_12005 PE=4 SV=1
NWRYRITWKPLATAA---PAAGPWLVLAPAAAR-----ALG---TDSVLVEVTAPDR------------E-----GRLRE--LLGTRFTGVASLLALADE
SVPGL-----PDVPVCL--TATAVQAVADTGIDAPLWCLTRGAVSVGRSQVTSPAQAAVWGLGRVIALEHPQRWGGLADLPEQLDP---HTLRRLAGVLA
-S-GEDQVAVRASGSYGRRLAHAPAARP---ARPAYAPAGTVLVTGGTGALGGHVARWLARSGAQHLLLTSRRGPDAPGA------GELRTELTELGAEV
TIAACDTADRDALTALLAVP-A--DRPLTAVFHAAGVVEDGLVEDLTPHGFSAVLRAKATAARHLHDLTQELDLAAFVLFSSTAGTIGAAGQGNYAAANA
YLDALAEHRR-ARGLAATSVAWGPWAGSGMVA-DGIENRVRRGGYAPLPVDQAVAALRHAVEHDDTTLVADIDWSRFARTLAAI----------------
------RPAPLVADLPEI------------RQSGD--QD--IAATPETGLRRRLAEL----PEAERGRFLLDMLRTQVAAVLGHARVEPDRAFRDLGFDS
LTALELRNAVTATTGLALPASLVYDHPTMLELAAFLLAELAG--------
>tr|L8EHG5|L8EHG5_STRRM Beta-ketoacyl synthase (Fragment) OS=Streptomyces rimosus subsp. rimosus ATCC 10970 GN=SRIM_32576 PE=4 SV=1
RFSYRVHWTPRTASG----ATGHWLVVLPEGGT--LLDALHDLGLHT----------------------D--EL-DPDAP--IADTPLDGVLSLLAL-DR
PHPDL-----PSVPRGL--TTTLLHALESAGVQAPLWCATRGAVAVDRHALDSPVQAQIWGLGRVAALEAPQSWGGLVDLPENLDR---RAVSALLDALA
-S-EEDQVAIRPAGTFARRLERIAPGGT----GARWSIHGTVLVTGGTGALGGHLAHWLADAGAEHLVLTGRRGPQAPGA------QELAAALTDRGVKV
TLAACDAADREALAAVLAIP-P--ELPLTGVVHAAGVLDDGVLAALTPERFETVLRPKARAAQHLHDLTQGMDLDLFVLFSSIVGVLGNAGQAGYAAANA
HLDALAAHRR-QQGLPATSVSWGPWAGEGMAT-D-AADRLSRDGLLPMAAAPALAALRQALAQDMTHVVADIDWSAYAPALTAV----------------
------RPSPLIGDLPEA------------RRAPA--D---GPRRERSPLRDRIAAL----PPAEQEQALVTTVREEAAKVLGHDTVDVQRAFREQGFDS
LMSVDLRNRLSAATGLRLPATLLYDHPSTVAVAAYLRSEVLG--------
>tr|R4LC06|R4LC06_9ACTN Modular polyketide synthase OS=Actinoplanes sp. N902-109 GN=L083_2493 PE=4 SV=1
GWRYRVTWAPVTKLG----VSGTWLVVRPAGVG------LAARGAEVVEADVRGL----------------------------DVGAVAGVLSLLAL-DS
SMVDF-----PSVPQGL--TLELVQALGAAGITTPLWIATRGAVATGADVLTSPIQAQAWGLGRVVGLEHPDRWGGLIDLPAVVDD---RASARLAAVL-
-C-NEDQVAIRAGAVLGRRLGHAPKPR-----DEQWQPRGTVLITGGTGAIGGHVARGLAARGASRVLLTSRSGPAAAGA------AELAASLASTGTRT
DVLACDASNRDELATVIATR-E-----LSAVMHTAGVLDDGVIERLSPSRLSTVLTAKATSAALLDELTAHRDLDAFVLFSSAASTLGSAGQGSYVAANA
YLDALAENRR-SRNLPGLSVAWGVWGGGGFAE-SAVRKRMQRTPMPPMDPDLAVRALFEAGHGADAALIMDVNWEQMAGGPRSM----------------
------RAMPLLRDLPEI------------RDLNE--PT--VPAIGEGELGRRLTGL----SRVDQERLLTDLVRVEAAAVLGHEGVPARSAFKDLGFDS
LTAVELRNRLSAASGLRLSATLVFDYPTPAVLASHLRAELTG--------
>tr|G2G4P4|G2G4P4_9ACTN Modular polyketide synthase OS=Streptomyces zinciresistens K42 GN=SZN_02237 PE=4 SV=1
GWRYRVSWKPVPDPAE-GPL-GTWLVVVPAARAGDVVAGLERHGAGVVSLVLDERDL------------DAG---GRLREVAGQ--ELGGVLSLLALDEE
PCPGH-----PALSGGG-R-LVLAQAMVEADVPARLWCGTRGAVSVGRSRLTGAVQSQVWGLGRVVALEHPAVWGGLVDLPESLDE---RGAARLAGVLS
AGKGEDQVAIRGSGVFARRLVRADASGG---AERPWRARGTVLVTGGTGALGGQVARWLARSGARHLVLTSRRGPDAPGA------AELRDELEALGARV
TVAACDVTDRDALAAVLADV-PE-EFPLSAVFHAAGVEQAAALVGMSLADAAAVVSAKTAGAAHLDELLGDRELDAFVVFSSIAGVWGSGGQAAYSAANA
CLDALAQDRR-ARGLAGTAVAWGPWAEGGMAAA--VERELARRGLRVMAPALAIAALQGAIEGGDTAVVADMDWERFAPAFTLE----------------
------RPSSLIGDLPEV------------AKAGAP-----GGAAASAGLRERLAGL----TEAETDRALLDLVRGHVAAVLGFETVDAGRAFKELGFDS
LTAVELRNRLNAETGLALSATLVFDYPNASVLADHLRAEVL---------
>tr|A0A0D0V4R3|A0A0D0V4R3_9ACTN Beta-ketoacyl synthase OS=Micromonospora carbonacea GN=TK50_11430 PE=4 SV=1
AWTYRVAWEAVHPAS--TRPPGRWLVVTPTLPAGTVVGALRRGGARVEVLGVRGGVG------------RGEALRGPGGQ--VAETGWAGVVCLLPE-RA
PLPDA-----PAVPAGT--LLTLAQALADTGLPGRLWCLTRGAVSVGGGRIADPSAAAAWGLGRVIALEQPDRWGGLVDLPGSGIRTSRAGGDALLAVL-
-A-GHDQVAIRPQGVLGRRLVPAAPP-V----GSGWRPSGTVLVTGGTGALGRHTARWLLANGAAEVVLASRRGPEAPGA------AELIEELRGTGA-V
RVVACDVTDAAAVDALVALP-A-----LTAVVHTAGIVDDGVLDGLDVDRMQAVLAGKATAARVLHDATAGRDLDAFVLFSSLAGVVGSAGQGNYAAANA
YLDAFAAWRH-AQGLPATAVAWGAWAADGMAA-AALTARLTRGGINPLPAAEAVTALGRVVNAAGPAVVADVDWGRLAASW--G----------------
------RPNPLIAALPGV------------PAVGP--------------VR----AV----VVGRSLPQLTELVRTQAAVVLGYRP-LPERTFRDLGFDS
LTAVELRNRLTAETGMTLPATLVFDHPTVAELAAHLHGLTNR--------
>tr|D9T6W8|D9T6W8_MICAI Beta-ketoacyl synthase OS=Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442) GN=Mica
GWTYRIDWEPVRPAA----ATGRWLVVTADA----AAGTLTGAGAHVDTLTVAPGVD------------RAELL--------RGEQGWTGVLCVLPA-TR
ALPDA-----PAVSVGA--LLTLTQALADAGLPGRLWCLTRGAVRVGAGTLTDPWPALAWGLGRVVALEQPDRWGGLIDLPARAE-R--TAADALLAVL-
-A-GHDQVAIRPQGVFGRRLVPAAPP-A----GAGWRPAGTVLVTGGTGALGRHVARWLLANGAAEVVLASRRGPAAPGA------AELVDEL---GA-V
RVVACDVTDRAAVDALVALP-E-----LTAVVHTAGVIDDGVLDGLDLGRMQTVLDGKVRAARVLHEATAHRDLDAFVLFSSLAGVIGSAGQGNYAAANA
YLDAFAAWRR-DQGLPGTAIAWGAWAEDGMAA--ALTARLARGGVDALPVAEAVTALGRLVNTADPAVVAAVDWGRLAASW--G----------------
------RPTPLIAALPGV------------PAVGP--------------VR----AV----VVGRSLPQLADLVRTQAAVVLGYRP-LPERTFRDLGFDS
LTAVELRNRLTAETGMTLPATLVFDHPTVAELAAHLHGLTA---------
>tr|C9YYI0|C9YYI0_STRSW Putative type I polyketide synthase OS=Streptomyces scabiei (strain 87.22) GN=SCAB_83891 PE=4 SV=1
GWRHRVGWRPLTLAPR-ASLSGRWLVVLPAADSGAVLAALTAAGAEPVPVVVSAPDQ------------DRE---ASLRAASGA--PVAGVFSLLAEETR
PHPAQ-----PDVPAGL--TLALVQALGDTGTDAPLWCATRALAAVGGGRPGASAQAAVAGLGRTVALERPDTWGGLVDLPAVLDE---RAADRLGAVLA
AVTDEDQVAVRSSGVYGRRLLPVGPGRP---AEARHSPSGTVLITGGTGGIGAQVARELAERGAVHLLLLSRRGPDAPGV------DALRAELTALGARV
TVAACDVADRAQLTAVVAAI-PE-EEPLTTVVHAAGVLDDGTLDALDPARLATLMRVKVTAARTLHEVTDGIGLADFVVFSSFMGVLGSAGQGNYAAANA
ALDALVAERR-AAGLPGTSLAWGAWAGGGMVDDR-IADRLRRLGITPMEPRAAVRAMTAALADHDELCVADVDWQRFREA-VGL----------------
------RATALLSGLPGA------------AGAPAGPAEQEGQEGQDGQVRGQLAAL----PAAERSRHITDLVRTHAATVLRHTDIAPGRAFAELGFDS
LTAVELRNRLGTATGLRLPTTLLFDHPTPQALAAHLLAELAP--------
>tr|A0A024Z3Y3|A0A024Z3Y3_9ACTN Polyketide synthase OS=Streptomyces sp. PCS3-D2 GN=AW27_07040 PE=4 SV=1
SWRYRVTWTPLSVAPA-DGLAGRWLALRPESDA--VLDALRDAGADLIPCVVAGPGT------------TRG---VLLT---DAGQPIAGVLSLLSWEER
THPQH-----PDLPGGP--TLALAQALEDAGIDARLWTLTTGTAALGGARPGTVGQAASAALGRTAALEHPHRRGGLVDLPEVLDA---RAARRLCAVLA
GVADEEQVAVRSTGIHGRRLRPAPSASP---VRPGPKWQGTVLVTGGTGGVGSHTARWLAGQGAERLLLVSRRGADAPGT------DALRAELTALGAEV
AFAACDVADPVALAALIDAI-PV-QYPLSAVIHAAGVLDDGVLDALDPARLAVVMRAKLTAARNLHEATAGLNLSAFVVFSSVMGVLGNAGQGNYAAANA
AVDALVAARR-AAGLPGTSVAWGAWAGPGMLADD-VAARLRDFGMPVMEPETAVTAIGRALAEDDALVVADIDWRRFTAG-MGL----------------
------RSTALLDALPDP------------AGADTGAPPSADGAHDADTLRQQVAVL----PRHERVRTLTELVRAHAAAVLRHNTVQPAKAFSALGFDS
LTAVELRNRLATATGLALPATVLFDHPTPSALADRLLAELG---------
>tr|F1ADL8|F1ADL8_9ACTN BafAI OS=Streptomyces lohii PE=4 SV=1
SWRYRVAWTPLSVEPA-DGLAGRWLALRPESDD--VLDALGEAGADLLPCVVDDPGA------------TRG---ALLTEITETDQPIAGVLSLLSWEER
PHPDH-----PDLPGGP--TLALAQALEDTGIDARLWTLTKGTAVLGGARPGHVGQAASAALGRTLALEHPHRPGGLVDLPEVLDV---RAARRLCAVLA
GVADEEQVAVRSTGVHGRRLRPAPPSAR---ARTRPLWKGTVLVTGATGGVGSHTARWLAGQGAERLLLVSRRGADAPGT------DALRAELTALGAEV
AFAACDVADPAALAALVAGI-PA-RYPLSAVVHAAGVLDDGVLDALDPARLAVVLRAKLTAARNLHEATADLGLSAFVVFSSVMGVVGNAGQGNYAAANA
AVDALVAARR-AAGLPGTSVAWGAWAGPGMLADE-VAARLRDFGMPVMEPETAVTAIGRALAEDDALVVADVDWRRFATS-TGL----------------
------RSAALLDGIPDP------------AAAGTTAPS--ETGGSADALRQRIAVL----PRHERVRALTELVRAHAATVLRHDAVRSTQAFSALGFDS
LTAVELRNRLAAATGLALPAAVLFDHPTPSALADRLLADLDL--------
>tr|A0A060ZUG5|A0A060ZUG5_9ACTN Beta-ketoacyl synthase OS=Streptomyces iranensis GN=SIRAN6342 PE=4 SV=1
PWTELAVWPPQGATPI-AVEQGAWRLGEEVGFPGAERFGLHAAGAGALRVRLSERSS------------NAVSLRDQVRAARGG------HESLFRLDWV
PAPAT-----GAVTGDWAAALLQEWLADERFAGSRLVLLTRGAVETEPGGVADLPYAAVRGLFRSAQSENPGRLVLLDVDGEESSY---RTV-----PAA
LGVDEAELALRAGVALAPRLARVPVTDV---TVPSYDPNGTVLITGATGTLGGLFARHLVAHGVRHLLLVSRRGADAEGA------EELGAELTAAGATV
TWAACDAADRHALAATLAAV-PA-EHPLTAVVHTAGVLDDGVLGSLTPERVARVLRPKVDAALNLHELTRDHELSAFVLFSGAAAVFGAPGQASYAAANS
FLEALAQHRV-AQGLPATALAWGLWAGAGMGSELVDLRRIARGGVAPIAADEGLALFDAARADGAAVLPMRLDYAGLRTEATA-----------------
-----------TGTVPAL------------FRGTPVRRAAATAAAEGSSLAQRLVGL----ARPEQDRELLELVCGRVAAVLGYDAVEAGRAFKELGFDS
LTAVELRNDLKTVTGLRLPATLVFDYPTPAALAGHLREELLG--------
>tr|I2NBQ7|I2NBQ7_9ACTN Beta-ketoacyl synthase OS=Streptomyces tsukubaensis NRRL18488 GN=STSU_00535 PE=4 SV=1
DWRYRITWQLSDTHPT-GPASGIWLLVGDDPDA--MAEALTRHGADVLTATDVGDL--------------------------DPVAEVTGIVSLLAL-DT
PDAEF-----PWVPSGT--TVELIQAVHRAGAAVPVWVLTRGAVQTGAGATTSPAQTAVWGLCRAVGLERPELWGGLVDLPADFTA---EAGTGLASIL-
-T-SEDQVALRPDGVFLRRLVHAEPRRE----TGKWTPRGTVLLTGGTGSIGVTVGVWLAEQNAQRVVLTSRSGPLAPGL------PALAASVANGGADV
DVLGCDLGTPEQVNGMVGIQ-ET-GPGLSTVLHTANLPYLAWVEDTEREGLAAALGAKAAGAVHLDQATTGLDIDEFVLFSSISATWGSNDHGAYAAGNS
FLDGFAETRR-SRGLPATSIAWGVWDSRDWDALDVTPSRLRRQGMNFLETQRALTALGEILTEDETFIVADVEWEKFAPVFCAA----------------
------RPRPLLDTIPEA------------REDPARPAQ--TATTERGEYATQLAPM----TLGERRRTVIDLVRSHATAVLGHDEINATRAFRDVGYDS
LTAVELRNRLNTVTGIRLPSTVVFDHPNPTALAEEILTELFG--------
>tr|A8J706|A8J706_9ACTN Modular polyketide synthase OS=Streptomyces cyaneogriseus subsp. noncyanogenus GN=nemA4 PE=4 SV=1
GWRYRVVWRPVSRSGG-GVVGGVWVVVVPEGVVGAVVEGLERAGVCVRVVAVEGGCA------------DRV---ERLREVCGG--PVGV----------
----------LAVCGGG-A-LVLGLVQAVEGLGVPLWCVTRGAVSVGEGRLGDPGGAVVWGLGRVAGLELPDRWGGVVDLPEVVDE---RVVEGLLGVLS
GGGGEGEVAVRASGVFVRRLVRAPGGGA---EAGGWRPRGTVLITGGTGALGAHVARWMVRRGAEHLLLVSRSGREAKGA------GELRAELTAMGARV
TIAACDVADRGALAELLAAV-PE-DCPLGAVVHTAGVVDDGVLDALTPERLEGVLAAKAVGARNLHELTRGADLSAFVVFSSAAATFGSGGQGAYVAANA
YVEALAVHRR-GLGLPSTAVAWGAWAGGGMAAD--AATRMDRRGIRPMDTEPALSALGQVLDRNETCLIADIDWERLPAADGLA----------------
------R---LLSDIPEA------------RLARPA-----TGTEAPGSLRARLAAL----EPAERDRALLDLVRTHTATVLGHTAVPADRAFRELGFVS
LNAVELRNGLNTATGLRLPSTLVFDYPNPSALATHLGTLLST--------
>tr|Q79ZM6|Q79ZM6_STRAW Type I polyketide synthase AVES 4 OS=Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12
GWRYREVWRPVSGGGV-GGLSGAWLVVSEGEAG--VAEGLERCGARVVRVEVEAGCV------------SRE---GHLREAVDG---VGGVVSLVGWGS-
---------------GV--SVGLVQALGDVGVGARLWCVTGGAVSVGGRAVWGPASGVVWGLGRVVGAEAPDRWGGLVDVPELVDE---RVVDGLVGVLA
GGGGESEFAVRSSGAFVRRLVRAPLEE----AEREWRPRGTVLVTGGTGELGAHVARWMARRGAEHLLLVSRRGESAQGV------EELRADLMGLGARV
SVVACDAADREALAEVLRAV-PA-ECPLGVVVHAAGVVDDGVLEGLSSERVTGVLRAKALAAWNLHELTRGADLSGFVVFSSAAATFGPAGQGSYAAANA
YVEAIVRHRR-GEGLPGLAVAWGPWAGGGMAEGA--VGQMRRRGLAAMTPETALVALGQALDHDETCVVADIDWDRFTANLPGS----------------
------RLSPLISDIPEA------------RLAGLD-----TATASPDSFSARLKAM----DTAEQERALLDLVRTYAATVLGHTAVRPERAFRDLGFVS
VSAVELRNRLNAVTGLLLPTTLIFDYPTPSALAGYLKEQLEE--------
>tr|S4Y352|S4Y352_SORCE Uncharacterized protein OS=Sorangium cellulosum So0157-2 GN=SCE1572_38665 PE=4 SV=1
QWPPLAGWSLLKEIEE-ASSLGSWGIAAGHSVGGSVVAELEPFRERTLVSTVTGEGI------------DGESYWEALGALHPA-----RCVPLPGYPWA
PADAG-----PEFAAQLGAGLAAWWAEGEDALDARLWFVTRGAVSVGAGPVTAPAQAALWGLGRTLSLEHPEVWGGLVDLPPSPGE---HDVAALAAVLS
--PGEDHVALRASGRYVERLVRCAGA-A---AAPAWSTSGTALITGGLGALGRHVARWAAQRGARHLVLTSRRGASA-GD------RDFLTSLEALGARV
TVAQADVADAAAMAAVLAID-AR-LPPLSAVFHLAGVSDQTPLSALDGAGLRRVLAPKVHGTAALDALTRGRPLDAFVCFTSIAAVWGSARQAGYAAANA
FQDALVRARR-AAGAPAVAVSFGPWRGGGMATSA--IASLEERGVRAFGPEQAMAALSFCMTAGAAQVVADVDWPRFCAVVESS----------------
------GPRPLLSEMPRV------------AAPGDAA---PAPGDAAPALLGELAAA----PPRERRRMLQRRIHALVAETLGFDEVSPTRGFFELGMDS
LMAVDLCQRLGLALGRPLSSSATFNHPNVVAMADFLLEELSP--------
>tr|D6C474|D6C474_9ACTN Modular polyketide synthase OS=Streptomyces nanchangensis GN=meiA4 PE=4 SV=1
GWRYREAWRPVGDGGP-GAPTGRWLVVAADGVD--VVEELERSGARAA-LHAAEGCV------------ARE---ERLRAELGP--EVDGVALLLAGSG-
---------------GG--LLVWLQALGDVGVAARLWCVTRGAVSVGGGAVVSPGLGQVWGLGRVAALEAPEVWGGLVDVPDPLDA---RAARSLVRALA
G--PERECAVRASGVFVRRLERAPLAGE---PGREWRPHGTVLITGGTGGLGAQVARWLAGRGPVHLLLLSRRGEAAEGA------AGLRDELAGLGARV
TVAACDVADRDALTRVLAGV-PE-DAPLTAVVHAAGALDDAVLATLTPERLEAARQAKAVGAWQLHELTRGADLTAFVVFSSAAATFGSAGQGGYAAANA
EVDALIQHRR-GLGLPGLSVAWGAWAGGGMADAAADAGRLRRHGMAAMDPRLALRALGHALEHDETCLVADIDWRAFVDNAPAT----------------
------GLDPLISGIPEA------------RTAGRG-----AAE-AAGTLRARLAGL----AADEQRRMVVELVRTHAAAVLGHAAVPPERAFRELGFDS
LTAVELRNRLNAATGLRLPTTAVFDYPHPAALAQHTYEQLFG--------
>tr|E2Q520|E2Q520_STRC2 Modular polyketide synthase OS=Streptomyces clavuligerus (strain ATCC 27064 / DSM 738 / JCM 4710 / NBRC 13307 / NCIMB 12785 / N
SWRYRIGWQPLPDAP----HTGTWLVLVPAPSA--CLRALRDAGAAVTRITLDGTET------------------ARLRA--ALAGPPAGVLSLLAT-DR
PHPRH-----PSVPVGT--GLALVQALGDAGIDAPLWWATRGAVSTGRAGPVSPAQNTAWGLGRVAALEHPRRWGGLVDLPADLDA---RAAARLCAVLS
GG-DEDQIAVRATGVHGRRLLRAPLAAA---PRRTWTPRGTVLITGGTGGLGAYLARRLARGGAEHLVLVSRRGPAAPGA------AELTAELTALGVRT
TVAACDITDRDALAALVDLE-RD-GCTIRSVLHAAAGGSLVALDDTDLDEFATTLHAKAGGAAHLDALFDRDTLDAFVLFSSVSAVWGSAVHGAYAAANA
CLDGLAENRR-ARGLTATSVVWGIWSPEHGGGMALAEEQLRAQGVLFMPPALCAAALQQILDHDETVVVADIDWSRFATVFTTG----------------
------RPSPLIGSVPEA------------RAAPNTPAD--TAGGAPAPLRDRLRDL----TGPERDLLLTDLVRTRAAAVLGHDTVTPDRAFRDLGFDS
LTAVELRNRLNEATGLRLPVTVVFDHTSPTALARHLRTRLLG--------
>tr|A0A0A0NM24|A0A0A0NM24_9ACTN Uncharacterized protein OS=Streptomyces rapamycinicus NRRL 5491 GN=M271_46360 PE=4 SV=1
EWRYRVIWRPKSGTPA-ASL-GPWLLLAPSSRPGDSREALAAHGADVVLVELGADDA------------HRA---ERLRAATAGLDTLSGVLSLLPLDER
PYPAH-----PVATTGL-L-LALIQALDDLGVRAPLWCATQGAVSIGSSPLTSPAQAAVWGLGRVAGVEYPDSWGGLIDLPRTMDA---RAGARFAGVLA
DGGPEDQAAIRASGVMLRRLEPAPLGNP---ARRTWKPRGTVLITGGTGALGSRLARWLAHNGAEHLVLTSRRGLAAPGA------EDLVAELAEQGTRV
TVAACDVADRAALQRVLASV-PD-DRPLTAVIHAAAYIDLAGLGATTSAEFAQVMDAKVAGAAHLDELLGDTPLDAFVLFSSVSGLWGVGDHGAYAAANA
YLDALAERRR-ANGLTATSVAWGVWDATGDNMP-LDLDQLRRRGLRFMDPELGIAALRQTLDHDQTHLIADIDWENFIPVFTSA----------------
------RPSPLLDELPAM------------RRIDPAGAVTNASADASSGLRQRLTGL----TPAEREHTVLELVRAQVVSVLGHDAVDSERAFKDLGFDS
LTAVELRNRLNAATGLRLPATLAFDYPSTAVLSDHILTELTG--------
>tr|F8JL01|F8JL01_STREN FscE OS=Streptomyces cattleya (strain ATCC 35852 / DSM 46488 / JCM 4925 / NBRC 14057 / NRRL 8057) GN=SCATT_p14450 PE=4 SV=1
PWT---PAPPADAERV-ELDRAMWRRGDEVLLP--GGFHLHATGATTLRVCLERSGD------------GPVRLWEDVPAGTGG---ADGDVTVVAAPDT
PAGAD-----PAQAAVWGATLGLYPGLGTEGAGVDGWTYARGLVEVGPGKVLVAAGHIARALGDVYATAHPAKWDTLRALGYPDSH---IAGSRDTGVLN
SGLDASVRLLRPGGHLLTRLYPEPPVTT---LPAPLDPDGTVLITGGTGALGADVARHLVTHGARHLLLTSRRGPAADGA------EQLREELARSGATV
TVTACDAADRDALAAVLSEV-DP-AHPLTAVVHAAGVLQDTTLAGLTPARLHAVLRPKADAAWHLHELTREEDLAAFVLFSSASAVLGTAGQANYAAANA
FLDALAHHRH-ALGLPATALDWGLWDRPGMTGALTDTDRLRRGGLRPMTTDEALSVLDAALRSPAPRMAAHLDRAALRAQ---G----------------
------SPDPLLRELLPA------------TVGRR-------TARGASGWARELTGL----TEDERRAAVRRQVRAHAAAVLGHESLGADRTFRDLGFDS
LTSVELRNRLTAGTGLPLSAAVVFDHPTVTALADHLLSLAAG--------
>tr|A0A0M8VVE6|A0A0M8VVE6_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. NRRL WC-3618 GN=ADL01_19130 PE=4 SV=1
RWMYRESWKPLAGLAP-AAFDGTWWVVAPADEGAHAAAGLEARGARVVRIAVGRDDA------------RREVVAGKLRELLDGVGHPQGVLSLLALDDS
EGS-----VHPTVAAGLEGVLVLLQALGDADVAAPMWAATCGAMTTGRDRLAAPAQAAVWGMGRVAALEQPQRWGGLVDLPAHADE---RAGLRLADALG
RPSGEDQVAVRGSGVFVRRLVRAPLADVSSGRSPEWSSRGTVLVTGGTGALGGHVARWLAGVGAEHLVLTSRRGPDAPGA------AELRAELEQMGVRV
TVVECDAADREALARVLDAIPED--VPLTGVFHTAGVLDDGVLDGLTAERFATVFRPKAQAALNLHELTRDSRLTAFVLFSSVAGSLGIGGQGNYAAANA
FLDAFAEHRR-SLGLPALSLAWGPWAGGGMAVDGGVEQRVRDSGMPPMAPDLAVAAMGALLAAGSAITLADVEWDQYAPTYAM---------------A-
------RPCHLFDQLTGPPV-----STEVSTTGP-DRRSAR--GATPSSLADQLAALP----AAERERALLDLVRERVATVLGYKTVDTTRPFKDLGFDS
LTAVELRNLIGAASGLHLPATLVFDHPTPAALVGFLRGEL----------
>tr|M3CU99|M3CU99_9ACTN Modular polyketide synthase (Fragment) OS=Streptomyces gancidicus BKS 13-15 GN=H114_17916 PE=4 SV=1
GPHHEIIWTPAQGLPDTARLSGRWLLVRSTLDGDDVTVALRAAGADVVTVEQHHLDR------------RTE-LSRRITAAAE--APVTGVLSVPAVGGP
---------ADDMTAGASATVVLLQALGDARVEAPLWTLTRGAVAAGADPASDPAQAAVWGLGRVAALEHPDRWGGLVDLPSELDR---RSAERLVALLA
DSPREDQVAVRADGAFARRLIPAAP-----PAEAAWQPAGTVLVTGGTGALGARVARWAAQQGAERLLLVSRRGAQAPGA------EALGEDLRRLGADV
TFAALDLTDRDAVRELLDAHP------VDAVVHTAGVIEDGVLDGLAPEAFRSVFAAKVTGARHLDELTRDRDLSAFVLFSSFAGTVGSAGQGNYAAANA
VLDALAERRR-AEGLPAKSVAWGPWAGGGMAADAGEGR-QVRGGVGLLDPDQALEALAAQA-GGSASLVADVDWSRFGAAFTA---------------V-
------RPSPLLAEVYDRPA-----ETRT--------------APASTALRDRLAGLT----PEDRRRELLAEVRTRAAAALGHGQVGAELAFRDLGVDS
LIAVELRNTLAAVCGVTLSATVVFDHPTPQALAAHLYDEL----------
>tr|A0A0F4IQV4|A0A0F4IQV4_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. NRRL S-495 GN=VR45_41010 PE=4 SV=1
SWRYHVVWAPLSVA-PADGLPGRWLALRPEDDAAA-LDTLGEAGADLLPCVVADPGA------------TREQLAVLLTTTAG-EQPIAGVLSLLSWEER
SHP-----DHPDLPGGPALTLALIQALEDTGLDARLWTLTKGTAVLGGERPGHVGQAASAALGRTAALEHPHRRGGLIDLPEVLDV---RAARRLCAVLA
GAADEEQVAVRSTGVHGRRLRPASPASPRVRTRPRWQ--GTVLVTGGTGGVGSHTARWLAGQGAERLLLVGRRGADAPGT------DALRAELTALGTEV
AFAACDVADPAALAVLVADIPAR--YPLSAVFHAAGVLDDGVLDALDPARLAVVLRAKLTAARNLHEATAGLDLSAFVVFSSVMGVVGNAGQGNYAAANA
AVDALVASRR-AVGLPGTSVAWGAWAGPGMLADD-VAARLRDSGMPVMEPETAVTAIGRAL-EDEAVVVADVDWRRFTTGMGP---------------W-
-------SAALLDGIPDPAA-----ARPVTTAPS---PARAG-GGSADVLRQRIAVLP----RHDRVRTLTELVRTHAATVLRHDTVQPGKAFSALGFDS
LTAVELRNRLAAATGLALPATVLFDHPTASALADRLLADL----------
>tr|A0A0M8VZL5|A0A0M8VZL5_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. NRRL WC-3618 GN=ADL01_19150 PE=4 SV=1
----------------------RWLVVLPENAAEHGSEALAQTGAEVVELKLPSAEL------------TRKTLSAQLRETAE--AGLAGVVSLLALDES
AHD-----TYKAVSVGLAGTVALVQALGDAGVGARLWALTGGAVATGRDRDTNPVQAQMWGLGRVVALEYPDRWGGLIDLPQAYDA---RAASRFAAVLA
GAGDEDQLAVRDTGVFVRRFTPAPVDA-GKGAEPEWAPRGTALITGGTGAIGGHVARWLAREGAEHLVLTSRRGLDAPGA------VELQAELEELGAEV
TIAACDVADWDAVTGLLDGLAAG--RTLRSVFHAAGVGQEQPLDTMTAADIAETLEAKVAGAAHLDAL-LETSLDAFVLFSSNAGVWGSGSQGAYAAANA
HLDALAEQRR-ARGLTATSVAWGLWGGGS-GMAGEAEDALRRLGVTAMAPERAIAALAEAV-YDETLAVADIAWERFAPAFTS---------------V-
------RPSPFIGDLPGVRR-----ALAGPITGS-AASGTKG-PVSGSEWAERLAVLP----TAEQERSTLDLVRAQAAAVLGHEAVEPGRAFRDLGFDS
VTAVEVRNRLAAATGLKLPTTLVFDYPDSRTLAAHLRREA----------
>tr|B9ZUJ6|B9ZUJ6_CHOCO Polyketide synthase OS=Chondromyces crocatus GN=cndA PE=4 SV=1
GMFCKVVWQQRPLARSTPSAHGIWLLLADRGGVAEQLRHVLARGERCVLLRSASSTDAAGPQSDALLPTSAEGYKQLFANMKQEALACRGIVSLWPLDTA
TPEDSLASLDASLQRSSTRVLDMIQGISRLPAAPRLWFVTGDAEATGVAAASTLTQAPLWGLVRAMAYEHPELQPTCVDVPSSTAL---AVVEALADELL
AGEGERQIRLREGARDVARLVRRPDFRPADPCGARIREDGTYLVSGGLGALGLATADWLVQRGARHLVLVGRGDPSA---TAQEQIARF----EQAGASV
KTARVDVADEAALTGLLTELRT-TMPPLRGVFHSAGVLDDGLLLQQTRERFEGVMRPKALGAWNLHVTTADAPLDVFVLYSSAAAILGSPGQANYCAANA
FLHALARHRR-AAGRPAHCIAWGPWGDVGLAAADERGARLAARGLGSLTPTQGKQALGRVLDQGEAEVVTPFNLRHWREFYPIA----------------
------ANSPLFAEISDAQP-----ERPE----RDRAPLS------GE----ELRRL----APDARRERLEAHVRDHLATVTRMARIQSDAPLMNLGLDS
LMSLELRNRLEASLRITLPATLMFGHASLGSLAGHLAERM----------
>tr|A0A089VKX9|A0A089VKX9_CHOCO Polyketide synthase OS=Chondromyces crocatus GN=croA PE=4 SV=1
DWFYEAQWEPRPRRGVAPSGNAPWILFADQGGVGQALEALLQSGEPCVLVTAASTYERQQADRYAIRPHHPEDLQRVIEVLGANPSGCGGVVHLWSLDAP
HPAEGVSALGKAMELGCVSALHLVQALADKSSRPRLFIVTRGAQPAGESRSVAVAQAPLWGLGRTLSLELQGLWGGLMDLDP------------------
--------------------------EPQGTAPPSLRGDASYLITGGLGDLGLRVAGWMVDRGARHLVLMSRTRLPERDASWVEAITAM----EASGATV
RHVAVDVADADQMRAFQEARRE-AWPPIQGVVHAAGVARPQSLLDVDDATLWETLRPKVTGAWLLHEMFEDAPLDFFVLFSSGSTLLSSPGLGSYAAANA
FLDALAHHRR-AQGKAASSINWGFWAEVGMAAREQRLGSSA---HQGFRPEEGLEILGGLLGELPVQRVMRVDWQQWRAHYPSA----------------
------ASAPFLSRLVEPVQ-----IQAP----AEV--LP------PD----VLRTL----TGWQRRSLLEAFLREQLALVLKSARVDEAAPLRSMGVDS
LMAIEFRNRLEASLGLVLPATLVWTYPTLSDLATHLATKL----------
>tr|A0A060ZNN9|A0A060ZNN9_9ACTN Short-chain dehydrogenase/reductase SDR OS=Streptomyces iranensis GN=SIRAN1996 PE=4 SV=1
DSLFQLDWQPVATSAP-AAAGGSWAVVGPDAGLGEAVGRA------------GGSYAR-----------------------------YADVPALSALDEG
ESVPETDGLAARVRESLSAALSSVQSWLGELAASRLVVATCGAVATEGEDVADLVQAPVWGLLRSVQTENPGRCLLLDHDPDHGQEISAVAADAVVRVLA
VDAEEPQLAVRGDTVLVPRLSRVAKPAVDLEASARLVSGGTVLVTGASGVLAGVVARHLVDHGVEHLLLASRRGLDAPGA--AELVAEL----EAAGASV
TVAACDVADREAVRELLAGIPA--EAPLRGVVHTAGVVDDGVVEGLSDERVQRVLGPKVDAAWHLHELTRDMGLEAFVLYSSAAATLGAGGQGSYAAANA
YLDALAQHRH-AHGLPALSLAWGHIAQERTAG-----------------------LLDAALATERPH-VLSMKVD-LKAT--------------------
--------RKRADAVPALMR-GL-VRAPYRKV--------AAGQQSAEAWKEQMALA----APEQREQLLLDLVLTHSASVLGHTGIDPDRALKELGFDS
LTAVELRNQLSTTTGMRLPATLVFDHPTPLAVAHYLDSQIRG--------
>tr|A0A0E2WWZ6|A0A0E2WWZ6_MYCAV Polyketide synthase (Fragment) OS=Mycobacterium avium subsp. hominissuis 100 GN=MAV100_14020 PE=4 SV=1
GELLDVAWSGIEPRDN-PIEAGGELVVSTRGAVGRPGEDV-------------ADLAGAAVWGLVRSAQAEHPYRARLRPAGRRALLELPGPPAWRLAAG
DARPGAAGVTDLVAVDRRLVTRVPPGWSMVAGIPVVFLAATGGVGMHGAEVFATASRGKWDTLRAMGFDDAHIADTLDFEQKFGAAPGGEFNDASLRLLR
VARAHPGVRYRAFDLMEAGPDRIAAMMTMPDGPA-GLSGGTALITGATGMAGAALARHLVRHRVPHLMLVGRRGEAAPGM--AELAAEL----RGAGASV
SVLSCDVGDRDAVAAMLAQVPA--RYPLRSVFHAAGVLDDAVIASLTPARIDTVLRAKVDGAWNLHELTKDLDLSAFVVFSSMAGIVGAPGQGNYAAANS
FLDALAIHRH-AHGLPALSVAWGMWEEPSAMD-----------------------LLDDALLGEQPL-VVGTRLDRAALAQHR-----------------
-----AALPPLLSEL---------AGRPARRM--------LTDMVSLTGLRARLAGM----NAEQRQAELVELVCGNAAAVLGHADVGPGDAFSDLGFDS
LTAVELRNRLKIATGLTLSPTLIFDHPTPAALAEHLGGQLAS--------
>tr|Q08QH0|Q08QH0_STIAD Oxidoreductase, short chain dehydrogenase/reductase family OS=Stigmatella aurantiaca (strain DW4/3-1) GN=STIAU_4029 PE=4 SV=1
EWVYEVAWPEKKHASQ-GADTGKWLVLADGRGLGDALATRLREQGACTVLRAGGEASGPGQLSVNPKDPAE---WQRVLGQLEAEGPFRNVVHLWSLDSG
SQLEETGSLPLLVQRLSRGSGQKAKLW----------LVTRGTQAV-GKEAVSVAQAPLWGAGRVLALEHPEMWGGLVDLSPEA---PAHELEALWQELR
MPDGEDQIAYRGAKRHVARLVRSDV---TPESPATWRDDGAYLITGGLGALGLQVSRWLVSKGARHLILASRSGLPDPGQ--WKAVQEL----QSMGASV
QVVRCDVGEQAQVASLIEGIRG--SVPLLGIFHAAGVSTHRSWQETDPELFSTVFRPKAAGAWLLHEYTRDMPLSCFVMFSSASAVWGAQGMAAYAAANH
ALDALAHLRR-SQGLAATSINWGRWTEGGMAA-----------------------LLGRLAGSKARV-VASVEWSRFKPLQEA-----------------
-----KRQRPFLENIVT--------AQPVQKA--------A-AGNARSELLLRLEEA----PSSRRRAILMDHVRVEVARVLGASRLEPQQGFFQMGMNS
LMSIELKKHLETSLRHGLPSTIAFEYPTVEAMTGFLAKEVPA--------
>tr|A0A0C1ZKG5|A0A0C1ZKG5_9DELT Malonyl CoA-acyl carrier protein transacylase OS=Enhygromyxa salina GN=DB30_02224 PE=4 SV=1
ALVYQLEWRPSRLRLP-RAPPGLWLVLCDRAAFGDALIAALAATGDCVRVEPGAAFTQVSSDHYRVDPARAEDMHALFGHVRERGEPCRGIVHGWSLTDA
QPLERS-DVAAVVHVLREL---VGQRWPS---PPKLWLVSRGAAPVR-DEAITTAGAPLWGLGRTLAQEHPGVFGGIVDVDPHATA--QAQAQALIRELR
APDGEVQIAYRDAQRHVVRVTRARVPA-APSTSAQCRVDGCYLITGGLGGLGLHVARELVNCGARRLVLMGRSALPQRHT--WAAIQGF----EREGVSV
HLAAVDVGDPDQVKAFLDQHRG--WPPIRGVVHLAGVLQDQILLRLDADMLAAVFRAKVVGAWVLHRALASYDLDLFVLFSSVAAVLGSAGQGNYAAANS
YLDALARHRR-ARGLGGHSINWGPWADVGVAA-----------------------SMRSLLASARIT-VMDVDWSRFARAHPT-----------------
-----LSASPPIAELVA--------AELAAQQ--------SAPTPKPGEAAAAILAL----PIPERGPRIVALLTAHIALAVGRESLEADRPMVELGLDS
LMGIELRARLEAQLGVELPMATLLEGPSIHVLADDLLARLSS--------
>tr|A0A0M2GG91|A0A0M2GG91_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces variegatus GN=UK15_38785 PE=4 SV=1
-SLFRVDWTPLPMAP-SAAAEGSWAVLDDSAGLATLLS---GEGAAVS-S-----Y---------------RDLAELAA---VDGRVPDVVVAAVPDRSG
ALSAGGEGLPEPVHETARWTLDLVREWLSHESGSRLILVTRGAVAVEGEQVPDPAAAATWGLVRSAQSEHPERF-VLADLDAAPAPG--T-AIALAAVL-
-AAGEPQAAVRSGAVRVPRLTRDVSSTPA--APPVWDAEGTVLVTGGTGALGALVARHLVAHGVRHLLLTSRRGLAAPG--AAELRDE----LTGRGARV
TVAACDVADRDALARTLAEVPAE--HPLRAVVHTAGVLDDGVLEALSPERVSRVLRPKADGAWHLHTLTRHLDLSAFVLFSSAAGVLGGPGQANYAAANA
FLDALAAHRH-AAGLPARSLAWGLWDQDGMAGALDDLERLRRSGMKPLSAEQGMALFDAACRAGDPVLVLRLDTSALPVEP-A-----------------
-AA----VPAPLRGL---VR------RPVRKR-------AGTG-GGALSLKGRLVAL----AEADRTRTLLELVRTEVAAVLGHAEIEPSRAFGELGFDS
LSAVELRNRLTAATELRLPATLIFDHPTPAALANRLRVELL---------
>tr|A0A0M2GB82|A0A0M2GB82_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces variegatus GN=UK15_38890 PE=4 SV=1
-ALFRVEWTALPATEELSGPTGDWVELVAEQTASGVPA---GGGER---------Y---------------ADLGALAAAVDAGRPAPEAVVHRVVPG--
---GDVGSLADVGYDVARAVLDLVQAWLADNTASRLVLVTSGAVAASDGDVRAPEAAAVWGLVRSAQSEHPGRL-MLVDADPATPAA--T---LPTAAA-
-RSAEPQLAVRGADLLIPRLARAPHDEAV--TGLVPDPDGTVLLTGATGALGGLFARHLVTHGVRHLLLASRSGARAEG--APELEAE----LTALGATV
TLVACDVADRDAVAALLAGIPAQ--HPLTAVVHAAGVLDDGLIDTLTPQRLDRVFRPKVHGAVHLHELTRDLNLSAFVLFSSVSGVVGSPGQANYAAANA
FLDALARHRR-AQGLPATSLAWGLWEGTGMTGTLDDLARMRRAGMIGLTAEEGLALFDAACAGADAAPVVRLALSALRRT--------------------
-GT----PSPLLRGL---VR------GPARRT-------ADTA-GPAGAFADRLARL----PAAERARLVLDLVRAETAAALAFDEVPPAKAFKELGFDS
LTAVELRNRLNTATGLRLPATLVFDYPTPTTLADFLTAELL---------
>tr|D9WB21|D9WB21_9ACTN Modular polyketide synthase OS=Streptomyces himastatinicus ATCC 53653 GN=SSOG_00527 PE=4 SV=1
-SLFRIDWAPLPSGSVTG--VAAVAVVGAEEALAPALR---DAGTEVR-V-----Y---------------ADLAALSA---ADGSVPDVVLAALPGA--
---RSRNEVVDTVHASAASALELVQDWLVEETRSRLVMVTQGAVTARADD---LAVASVWGLVRSAQSEHPDRI-TLLDLDDGSVSG--A---VLSRAL-
-AQPEPELTVRQGRVLVPRLTRMPVPEL---RAASWEPRGTVLITGGTGGLGAVVARHLAAHGVRDLLLLSRRGMASPG--AEALVAE----LAGLGARA
EVVACDVADREALAKVLG----G--HEVSAVVHSAGMLDDGVIGALTPERVDAVLRPKADAAWHLHELTRDLDLSAFVVFSSAAGTFGSAGQGSYAAGNA
FLDALVRYRR-DRGLPGVSLAWGAWDQDGMVGELSDRERMHRSGFPPLSVEQGVALFDAAVGAGEPVVLVRVDLSVLRAR--------------------
-GE----VSPLLRGL---IR------TPFRRA-------AVTG------LAQRLSGL----GEVEQGEVLLDLVRSQVAMVLGHAAIDPGRSFRDLGFDS
LMAVELRNGLGAATGLRLPATLVFDYPTAQALADHLFDELL---------
>tr|A0A0F0GCW4|A0A0F0GCW4_NOCAE Uncharacterized protein (Fragment) OS=Lechevalieria aerocolonigenes GN=UK23_47790 PE=4 SV=1
-SLFRIEWAPVELPV--GFAEQTVAVLGPDVL----SL---AAGPVVS-E-----L---------------TD---------AD-------LTLVPVV--
---------GTDVRETCARVLSIIHE----AGTGRVAFVTRGAVD-----GDDLAAAAARGLVRSAQSEHPGRF-VLVDLDFAEASV--G---AVLHAL-
-TTDEPVLAIRDGVVLAARLARAALPAE----RVAW--SGRVLITGGTGGLGQLVARHLVAHGVRELLLVSRTGSADV--------SA----LESLGADV
IVEACDVSDRSALESLLS----R--HSVGGVVHTAAVLDDGVVESLDPSRLDVVFRPKVDAALHLHSLLPDV---PFVLFSSAAGTFGGAGQANYAAANA
FLDALARVRR-ASGQHAVALAWGAWEQSGMTASMSDMQRIARSGMPPLTVAEGLALFDAGAAGSDAFLLLRLDLPALRAQ--------------------
-GA----PPPLLRGL---IK------TPKRRA-------AAQS-V-AEGLVAELSRL----GSDARLDALLDLVAVEVAAVLGHSEVDRTRTFQGLGFDS
LTAVELRNRLTASTGIRLPATLIFDYPTAGALASFLLDELF---------
>tr|A0A086GIC6|A0A086GIC6_STRSC Uncharacterized protein (Fragment) OS=Streptomyces scabiei GN=IQ62_43715 PE=4 SV=1
-DLYTVTWIPADAPSLEPASTTR--HTGADDLLAAAST---A----------------------------------------SDTPYAELVVVPWQTP--
---DPETALVPGVHDATARALILLRHWLTDAVGSRLLVLTRGAVAAHDETVTDLPAAAVRGLLKSAASENPGRF-LLLDTDVTPTDD------QLADAV-
-RRGHDELVLRDGKLFAPSLNRVRDTPPP--AGVVFPTDRTVLVTGGTGAVGAAVVRHLVTHGVRRLLLVTRRGPQTPG--AAELVDE----LAAHGART
TVVSCDAADREALADVIDALPPE--YPIGAVVHAAGVLDDGVITSLTPVHLTRVLRPKADAAVNLHELTRDLGLSAFVMFSSAAATLSSPGQGNYVAANA
FLDAYAARLR-ADGHPAVSIAWGLWETSAMTRGLATHKRAARSGVDALPTGDALVLFDRALTHTEGTPLLCLDRTALRRA--A-----------------
-DR----LPPLLRSL---TG------RPALRE-------AAAR-PA--ASPLGLSHL----PESRRRDAVADLVRTTLAAVLGHTPIRPDTPFTQLGLDS
LTALELRNSLSHATGTTLPATLVFDHPTPEAVVDLLLAGLT---------
>tr|A0A0F5ABA6|A0A0F5ABA6_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. MUSC164 GN=VT50_17780 PE=4 SV=1
-SLFRLEWAPVPSPSAPA--AVRWAVVGEQAALVDALE---SIGAECA-V-----F---------------PDLSGLAAVVASGSPRPDVVLLPLTGP--
---TGDGHVAEDARLAAHEALDTAQSWLAEEAGARLAFVTRGAVATSDAAVADLPHAPVWGLIRTAQTENPDRF-LLLDLDGEGAP-----AGALMAAA-
-AGGEPQLAVRAGALHAPRLARVATQGEQ--GLPEFDPDGTVLITGATGVLGGQLARHLVARGVRHLLLNSRRGQRAQG--MPELVDE----LTALGAEV
SVAACDVADRSALSLLLAEVDPE--HPLAAVIHTAGVLDDGLLPALTPERIDTVFRPKVDAALNLHELTADLGLRAFVLFSSAAGTFGAPGQANYAAANT
FLDALAAHRR-SAGLPALSLAWGLWEQSAMTGGMADVARMERSGMAPLTSRDGLELFDTAGSVGEAVLVLHLDVAPL-REA-E-----------------
-GA----LPAVFRGL---VR------APARRR-------TVSA-GAGPSLARRLAGL----AEPEREKAVLDLVLGQAAAVLGFEAVGAARGFLEQGFDS
LTAVELRNRLGAASGLRLPPTLLFDHPTPELVARQLLAQLA---------
>tr|A0A0F5A7C0|A0A0F5A7C0_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. MUSC164 GN=VT50_27220 PE=4 SV=1
-SLFELDWTTIEAGPREPV----TAVVGSAAGL----------------------------------------------S--HVERAPDVVVYRVDGA--
---------PAEVTDAVSATLAVLQQWIADDVSSRMVVVTRNAVSCPGDQRTDLVGAAVTGLVRSAQSEHPDRI-VLVDVGDTDDTD--D-IAALGWTS-
-GIGEPQLAIRCGRVLVPRLRKTTSPPS---AEPGWAGDGTVVVTGATGGLGALVTRHLVDHGVRRLLLLSRSGMAAPG--VEALVAE----LGERGADV
RVAACDVADRDALAGVLAALPPG--AEVTGIVHAAGVLDDGVLASLTPERVAGVLAPKAVGAWHLHELTRDMPVRAFVLFSSIGGVLGSAGQANYAAANA
FLDGLAHHRH-QLGLPATSLAWGLWAGQGMGAGP-GPKRPVRGGVAPLSEAEGLALFDLLATADRPFVVARLQPGELRDRD-T-----------------
-GY----LPAVLRRL---VR------TAPRRR-------TVRG-QE---APADFAAL----DDAARARALTDLVRDRVATVLGYGEVALEKGYLDMGFDS
LTALELRNDLSAAVGLRLPATLLFDHPTPATTVRRLGELL----------
>tr|A0A0A0NT19|A0A0A0NT19_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces rapamycinicus NRRL 5491 GN=M271_46380 PE=4 SV=1
-SLYRLRWDAMPPLGDPS--TARCAVIGEEDGLAVALR---SAGWQVR-T-----H---------------PDLGALARSGAEGESLPEWVLLASATG--
---TG-GDTRQGLRGAAHQALERVQEWLAEEADSRLVITTRGAVATTTEGVDDLAGAAVWGLVRSAQAEHPGRL-LLLDADGPMGL----GSVPLAAAL-
-ASGEPQLAVRGGRVLAARLVRAEGT--G--ASATWDPEGTVLITGASGTLGGLLARHLVAHGVRHLVLLSRRGSAAEG--AAELADE----LTSAGASV
TWAACDVADRDALSAVLSDIPAA--RPLKGVVHAAAVLDDGVIASLTPERLDTVLRPKAEAALALHELTAGLDLSAFVAFSSVAGMFGAAGQGNYAAANA
FLDALVSQRR-AHGLPGLSLAWGLWEESGMTEGLADRRRMDQVGISALSSTEGLALFDAACAGG-PVIAARLNTTVW-RSG-F-----------------
-VE----VPHVMREL---VR------VPARRV-------TAESTGAAEALRARLAGA----SYAEGERLVLDTVRRNVAAVLGHETVEPGRAFKDFGFDS
LTAVELRNRLGTVTGLRLTATLVFDHPTPTALAQHLHHELT---------
>tr|A0A014M3I0|A0A014M3I0_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. PRh5 GN=Z951_46895 PE=4 SV=1
-SLFQLNWSLLPGAGTVE--SAVADVT--------PLD---GVDWHDI-A-----A-----------------FG--EAIGAEGAVPPAVVCVPPYV---
----P-TTDGDAIRDVIHRALELVRGWLAEEAGSRLVIATHGAVTVEDEAVVDLAAAAVWGLVRTAQTEHPDRF-VLVDLDGGDREP--EHLSLLSAAV-
-ASGEPQVAVRGGRLLAPRLGRVRPAETV--RSVVWDPEGTVLVTGATGTLGGLVARHLVAHGVRHLLLVSRRGADAPG--ARALEDD----LVAAGASV
SWAACDVADRDALTAAVKGVSDP--HPLRGVVHTAGVLDDGVIASLTPERVDAVLRPKMDAAITLHELTEAVDLSAFVVFSSAAGTFGTAGQANYAAANA
FLDALIRHRR-TSGLPGLSLAWGLWDEDGMAGGLADLRRMGRAGVDGLSPEEGLALFDAGCAGLPVVI-MRLDPAK----A-D-----------------
-GE----VPHIMREL---VR------PMARRA-------AAEGTGD---LRERLAAS----SEEDGERLVLDLVRRCVATVLGHAAVEPGRAFKDFGFDS
LTAVELRNRLGTATGLRLTATLVFDYPNPIALARHLHQELT---------
>tr|A0A081E987|A0A081E987_STRFR Uncharacterized protein OS=Streptomyces fradiae GN=SFRA_32405 PE=4 SV=1
-SLYRVEWQPRLLPAGPR----SWAVLGPDADLG--DQ---PDGGPTA-L-----Y---------------PEVRALRKALAAGAPRPEAVVLPVLSG--
---A--GATPESVRQTTERCLTALQDWLDAEVDTPLIVLTRGAVAAVGEEIGDLACAGVWGLVRSARSEHPGRF-ALVDTDGHPDDR--TALPLALRAV-
-LDGAGQLSLRAGTARTPVLLRAGT---Q--RGPAFDPAGTVLVTGATGTLGRLLARHLAAHGVRHLLLLSRGGRAAEG--ADELAAE----LAGLEAEP
CFAACDAADREALARVLAEVPAD--RPLTGVIHAAGVLDDGTLDALTPERIGTVMRPKADAALNLHELTRTSPLSVFAVFSGAAGILGRPGQANYAAANT
FLDALAQHRR-AHGLPAVSLAWGLWGGTGMTGHLSDLRRMRRSGIAPMTHDQGLALFDRALAAEDPLLVMRLDLAALVREG-P-----------------
-DA----VPGPLLGL---LP------ARARQA-------AAPVRPAGEGTAERLAGL----GEEARLRELVRLVRAEVSGVLGYDAVEPGRPFKDLGFDS
LTAVELRNRLGAATGLRLPTALVFDRPTSQAVAEYLAAELA---------
>tr|A0A060ZDJ3|A0A060ZDJ3_9ACTN Short-chain dehydrogenase/reductase SDR OS=Streptomyces iranensis GN=SIRAN1038 PE=4 SV=1
GWRYRVSWKPVPEVAA-GPLSGTWLLAVPASLADSTISALEKSGARVVPVAVDTD------------ADRDGLARA-LLAAV-DGESDVRVLSLLALDEE
PYAG-----EPVVASGLALTLWLVQAVAGLGMRVRLWCASRGAVSVGRSDRASAAQAQVWGLGGVAALEHPQIWGGLVDLPETLDE---RAVSRLVGLLS
VEGGEDQVAVRGSGVFAKRLTRASAPEA--TDADGWRASGSVLVTGGTGGLGGHVARWLARTGAGHLVLTSRRGMEAEGA------AELKAELEGLGARV
TVVACDAADREALAAVLNGLPR--EFPLTAVVHTAGVLDDGVLDALTVSRAAGVLRPKVDAARNLHELTAGMDLSAFVLFSSAAGTIGGPGQGSYAAGNA
YLDALALRRR-ADGLPATSIAWGAWAGSGMAVDGELEEQMRRGGMAPMNPELAISALQRALDLDEFLLVADATWERLAAELGG-----------------
-NR----PAPLLAELTETQR-PT--ASPV-----P--ADPAATESAASELRASLEAL----PSAKRQRNLRKLVRQHVAAVLVHDAIENDRSLTELGFDS
LTAVQLRNRLGAITGLDLPTTLAFDYPNLTALAAHLETGMF---------
>tr|A4F5C5|A4F5C5_SORCE Polyketide synthase OS=Sorangium cellulosum GN=spiF PE=4 SV=1
AWRYRVVWRTLEAPPA-GDVAGRWLIVARAGVAEDSLALLEARGAEVVHLRLGGD------------DARRERTAARIREAIGDAGAVRGVLSLAALDDG
TRWR-----DASLPAGLALTLGLVQALGDVGVAAPLWLVTRGAVSTGRADLGSATDAMIWGLGRVVGLEHPERWGGLVDLASGVDA---TALDRLAPFLA
SRDGEDQLALRPTGIFARRLVRAPLGDT--SPARPYTARGTSLVTGGTGALGAHVARFLVGRGAEHLVLVSRRGEDAPGA------GALRAELEALGARV
TLAACDVADRASVAALLARLDAQ-GDPVRAVVHAGGVVAQATLASTDLDGVRAVIAAKVLGALHLHELLGDRELDAFVLFASGAGVWGSGQQGAYAAGNA
FLDALAEVRR-AAGLTATSIAWGAWAGGGMLADHDAEEHLRRRGLAPMAPALAVVALAGALDHDETITVADIDWARFAPAFAS-----------------
-AR----SRPLLFDLPDARD-AL--EPTS-----E--PAGARAAGEDRALRDALRLL----SDAERAHRLVALVVAETAAVLGHSAIDPHKGFFDLGLDS
LVAVELVRRLHARTGVKLAATLAFDHPTPDALARHLDAELA---------
>tr|A0A0C2JPT3|A0A0C2JPT3_9ACTN Polyketide synthase OS=Streptomonospora alba GN=LP52_11215 PE=4 SV=1
EPRLGGRWLLLDRER----------------------------R---IAEQLRRHG----------------ARVDTEVLDDA-----------------
---G-----LPR---ALA----CIQAFADADIDARLWVATCGAVAVGDSEHRHADQAAVWGLGRVAALELPERWGGLLDLPTGPAE---AHGRRLVGALL
-DGAEDQVAIRTAAAYGRRLRPTEPA--R-KDPPHWRPRGTALLTGGMGGIGAQVARWLARLGAPRLVLTSRRGADSPGA------EELAAELRAIGADV
ELAACDAGDPAGLAAIKKRAAES-GHPVRTVMHMAGAGVLRGLADTDLQEYSETAYAKVAGADALDELFSPDELDEFVLFSSISAAWGSGDHGAYASANA
YLDGLADRRR-GRGLPARSVVWGIWAPRDGMAADAEDQS---RGIPFMDPQTALEGFHRLL-GDGVEVLADVDWERFAPVFTM-----------------
-AR----PSPLLETVPAAQA-ALR-RD-------R--E--QSGEGAEDSLAERLAAM----RPVDRTRTLGDLVRSQIAAVLQYEDVDPDRALRELGFDS
LTAVDLRNRLGAATGLRLPVTVVFDHPDAAALAAHIGGLLI---------
>tr|A0A0B5FA22|A0A0B5FA22_9ACTN Acyl transferase OS=Streptomyces albus GN=SLNWT_7325 PE=4 SV=1
DATLGGTWLLAVPEG----------------------------A---VREALEANG----------------AATVLVEVPDG-----------------
---G-----LSQ---GLA----LVQALGDRGIDAPLWLLTQGAVATQAAEPLSPAQAAVWGLGRVAALEHPQRWGGMIDLPGGTDG---RVTTRLCGVLA
GYGEEDQLALRSSGVFARRLVRATAP--A-PTGAPWTPRGTVLLTGGTGGVGAQIARWLARNGATHLVLTSRRGPQAPGA------DTLRAELAELGAKV
TIAACDVADREALAALVAEVEAE-GPPIRTVMHIAGAGVLVPLADTDLAEFADTAEAKVAGAAHLDALFDKDTLDSFVLFSSISAVWGSGEHGAYAAANA
YLDALAEQRR-SRGLAGTSVVWGIWSPEEGMAANAEEQG---RGIPFMAPKTAIDAFQEVL-RDEVVVVADVDWERFVPVFTS-----------------
-AR----PSPLLGRVPEVAR-ILA-AA----------ETPDDGGAESSSLRTRLAGM----SAGDRQAALLSLVRTQIAAVLGYEAVEVTRAFRELGFDS
LSAVDLRNRLGTATGLRLPVTVVFDYPSAAELAGHLGGELF---------
>tr|G2NZJ0|G2NZJ0_STRVO Acyl transferase OS=Streptomyces violaceusniger Tu 4113 GN=Strvi_3797 PE=4 SV=1
DAALTGTWLLVAPAG----------------------------A---VRDGLETHG----------------ATVVTVEAA-------------------
---G-----VPM---GLA----LVQALGDTGVAAPLWLATRGGVSVGGTDVDSPAQAAVWGLGRVAALEHPQRWGGMIDLPG-TDG---RVTTRLCGALA
GLGDEDQLALRPSGVFTRRLVRAAGH--R-GSGASWTPEGTVLLTGGTGGVGAQIARRLAQAGAEHLVLTSRRGPEAPGA------DKLKAELTELGAKV
TVAACDVADRAALEALVREVEAE-GPPIRSVLHIAGAGVLVPLADTDLAEFADTAEAKVAGAANLDALFDRDTLDSFVLFSSISAVWGSGEHGAYAAANA
YLDGLAENRR-ARGLTATSVVWGIWSPEEGMAANAEEQG---RGIPFMTPRLAIDAFWQVM-GDEVVVVADVDWERFVPVFTS-----------------
-AR----PSPLIGQVPDVAR-ILA-AD-------A--DTGADATGESSSLRDRLADL----APADRQAAVLSLVRSQIATVLGYEAVDAQRAFRELGFDS
LSAVDLRNRLGTATGLRFPVTVVFDYPSAEELAGHIGAELF---------
>tr|Q7WTF0|Q7WTF0_9ACTN NanA6 OS=Streptomyces nanchangensis GN=nanA6 PE=4 SV=1
SWRYRVGWRHLPDLGP-AAVAGPWLLVVPPKGA-DACEALTADGGEVRRLVTDGR------------A-DVAELAASLRALYAEGPSPAGVLSLLPLDER
PHEA-----FPAVTGGVTGTHVLLRALLDAELDAPLWCATRGAVAVDDDEAEAPAQAQVWGLGRVAALEHPTAWGGLVDLPASVAD---LAPDLLCAVLA
GRNGEDQVALRPAGAFGRRLLPAPLDAQAPAQERAWTPRDGVLVTGGVAGAAALVARWLAADGTKHIVLLAPDGPAAPGG------AELVAELAELGAEA
TVVDGVPSEPTTRQELADRLAAS-GLRVRTVVHAGAPGDWAPLAELTPDELAEALSDAMGGADRLAELCGLEPDDPVVVFSSIAAVWGGGGHGARAAADA
YLDAWARRRQ-AAGGHVARLAWGVWDGSED-----PEARAERQGLLALHPTPALAALRRTLSRSDHAVIADVHWDRFVPLFTM-----------------
-AR----ASRLFDEIPAARR-AW--QAAL-----D--SSDDESSESLTALRDRLAAQ----SPQARTGTLLALVRAHVAGALRYESVDPEQPFKELGFDS
LAAVEFRNRLRGAIGLTLPATLVFDYPTPTALAGYLVSQVL---------
>tr|A0A0N1JVN7|A0A0N1JVN7_9ACTN Beta-ketoacyl synthase (Fragment) OS=Streptomyces chattanoogensis GN=ADL29_38580 PE=4 SV=1
GWRQQITFTPLTRTPS-HTPAGTHLAVIPAGHEQDDVLALGPDT---VRLT--AP------------GTDRAALADLLRQQAAEGPQFTTVVSLLALAAH
PAHH-----PAHAPEALALTTTLIQALGDADLAAPLWCVTRGAVAAAPGEPSGPAQAAVWGLGRVAALEYPQRWGGLIDLPGTLDD---RSAARLADVLA
APGGEDQIAIRPSAVLGRRLVPVPAG----RSTREWNPTGTVLITGGTGALGTHVARELAGAGAPHLLLLSRRGPDAPGA------DALRAELTALGADV
TLTACDAADRDALAKVLADIPE--TAPLTGIVHTAGVIDDGVLDSLTPDRFEDVFRAKAASALALHDLTKDLDLAVFALFSSSSGAVGNAGQANYAAANA
CLDALAEQRR-AQGLAATSLAWGVWGGGGMAADQRAADVARRTGIRPLDPDLAVVALRRAVMG-RTEVVADIARDRFVRSFTA-----------------
-VR----PSPLLGEPAVDAG-HP--A-----------AGDTGEDTTGDALREKLTGL----PPAKRTEAVRDLVRTRAAAVLGHDAVAADRAFRDLGFDS
LSAVELRNQLGAATGLNLTATLVFDHPNPAALAAHLLSLLV---------
>tr|A0A0M8QC85|A0A0M8QC85_9ACTN Beta-ketoacyl synthase (Fragment) OS=Streptomyces caelestis GN=ADK41_37290 PE=4 SV=1
GWRQRIAWRPLNRSGP-GAPAGAWLAVLPAGHADDEVLLLGPAT---VRLE--AD------------RADRADLAVRLRRLQEDGHPFTGVVSLLALAEG
YDPQ-----APGTPRGATLTTALLQALGDARVDAPLWCLTRGAVAVSPGESPAPLQAAVHGLGRVAALEYPHRWGGTVDLPETLDA---RSAERLADVLA
DPGGEDQLAVRPAAVFGRRLAAVRPG-----APRDWQPTGTVLITGGTGALGAHVARRLAGAGARHLVLLSRGGPDAPGA------GKLRAELAELGAEA
TLIACDTADRDALAAVLADIPR--HAPLTGVVHTAGVLDDGVLDGLTPERFETVFHAKVTGALLLDELTRGHDLDVFALFSSASAAVGNPGQGNYAAANA
VLDALAERRR-ADGLPATSVAYGAWGGDGMAGDGRAAALAQRTGIRPLDPDLAVLALRQAVTS-DVAVVADVDPERFVRAFTT-----------------
-VR----PSALLTEMPAHAA-LT--A-TA-----A--AAGHDADRAVSDLRDRLARL----PGNRRLGTVLTLVRERAADVLGHDLVGPDRAFRDLGFDS
LGAVELRNQLGAATGLTLSATLVFDHPTPAALAEHILGELL---------
>tr|Q79ZC6|Q79ZC6_STRAW Modular polyketide synthase OS=Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / 
GEAAPAVWPPRGAEPF-HGLRAAWTVRLPQELHEFVSVATGATA---LRVTLTPAG----------------ANAVSLYAADGTGAPVVTVGSLLSLTWT
PVPG-----HPAVARERAARAWVSEDLDERLAPVPLVVVTRDAVGTSADDPTGLGSAPLWGLVRSVQSENPGRFV-LLDTDGDPSG---RSV---PGAV-
-ASGEPEIALRGGSALVPRLSRMAVTELPGTGLDALDPSRTVLVTGATGGLGTLVAGHLAEHGVRHLLLLSRRGPEAEGA------EELVGRLEKLGATV
TLVACDAADREALAAVLAGIP-A-AHPLTAVVHCAGTAENALLAALTPELIDRVFRAKVDAAVHLHELTEGLDLSAFVLFSSIAGTLGGTGQGNYAAANT
FLDALARHRR-GRGLPATSLGWGLWAAERGMGGGTDAAGTPMRGVSALPSD--------------GLALFDLGWRCAEPVVFP-----------------
-AR----LNAAAGSLPPVLR-GLF-RGPAR----R--TAEAGGQDSGAQLRRRLAEL----MPVERQETLLALVRDRIAAVLGHDRIETDRPFRDLGFTS
LTAVELRNRLNAATGLRLPVSLVFDYPTLGELVELLAGKLV---------
>tr|Q0ILC8|Q0ILC8_9ACTN NlmA5 OS=Streptomyces nanchangensis GN=nlmA5 PE=4 SV=1
GKAEPADWPPRGAERF-RGLRAVWSIELPQELHEFVSLATGATA---LRVALSPAG----------------KSAVSLRAVDGTGTPVVSIGSLLSMVWT
PVPE-----LPALTRERAARTWVSEELDERLASIPLVVTTTDAVGISADDRAGLGSAPLWGLVRSIQSENPGRLV-LLDTDGSVSG---RAV---RAAV-
-ASGEAQLALRDGVALMPRLNRPPAADVPGTELDALDPSGTVLVTGATGGIGALVATRLAKHGVHHLLLLSRQGPDAEGA------GELVHDLEELGATV
TLVACDVSDRAALAAVLDGVS-A-GHPLTAVVHCAGTAENALLASLAPELIDRVFRAKVDAAVHLHELTAELDLSAFVLFSSIAGTLGGTGQGNYAAANT
FLDSLAQYRR-RNGLAATSLGWGLWATERGMDSHAEGAGSPMGGVSAMPAD--------------GLALFDLGWRRAEPVVFP-----------------
-VR----LNAAAGSLPPVLR-GLV-RVPAQ----R--SAQTGSQAPESQLRHRLAEM----GPAERQETLLALVRDRIAAVLGHDQIETDRPFRDLGFTS
LTAVELRNRLNAATGLRLPVSLVFDYPTLGALVALLVARLA---------
>tr|D9WQ84|D9WQ84_9ACTN Modular polyketide synthase OS=Streptomyces himastatinicus ATCC 53653 GN=SSOG_05758 PE=4 SV=1
ATFDLAAWPPTDADEF-QGLEAAWRIRLPEGAEAFVSLAVGASA---LRVRLAGT------------TTGT--VSLQL--ADVTGAPVASVEALFSLTWT
PLPA-----APHAPNGAAAASPARPALEDRGLGAEPRVSGRGGVGESPSPAANLAHAAVRGLVRSAQAENPDRLV---LVDTDAED---TSLKTL--ATA
VATGEPQVAVRNGEILAPRLARTATT----AEANAWNPDGTVLLTGASGTLGALFARHLVARGVRHLLLVSRRGDQAPGA------ADLTTELTDLGATV
HWSACDVADRTALAETLATVPT--ARPLTAVVHTAGVLDDGVIGSLTPDRLSTVLRPKADAAWNLHDLTQHADLKAFIVFSSAAGVFGGAGQGNYAAANA
FLDALAQHRA-ANGLPATSLAWGLWAVAGGMGGEDETERIRRGGIGVLTADTGLELFDAATTASELLVPMPLDMAALRAQAG------------------
-VG----MLPPLFRGLVRAA-PA--RRAA-----E--SAATAGAGGADELRARLAGL----SEPERDEAVLELVCTQVAAVLGYETVDPARSFSEVGFDS
LTAVELRNRLNATTGVRLPATLVFDYPTPNALVQYLRGEIL---------
>tr|D7F1M9|D7F1M9_9ACTN Polyketide synthase OS=Streptomyces longisporoflavus GN=tsnAV PE=4 SV=1
--RYRLRWDPVPDPVD-HSAPGNWLAVLPPALATDGITALTAHGHRVVAFVADPDG----------EPSPAELLRAQLAAGAPDGTPFTGVLSLLALDER
PHHD-----HPAVSVGTALTAALVQGVAAAARPVPVWGLTRGAVAVEASDG-RPEQAPVWAVLQAAAAELPTWSGGLIDLPGTLDD---DAGRRLAAFLR
G-SAEQQVALRPAGLLARRLSPLPTD-----GSDVWQPGGTVLVTGTDTPYGAHAARWLAAHGAEHLVLLA----------------EAPTGLAETGVGL
TLWPYDPTDHDALAALLA------DTPVTAVIHTTGAAHTDP-------------RTALATAHHLDRLTRDRDLAAFVVFSDLSGTLGLPGTGAQAPLHA
RLEALTDARR-AAGLPAATLAFGPLTE-----------HLAPLGVRPLAPKPAMDVLGRIP-RGATTVVADIDWARFTAEPN------------------
-NA----PLALLREIPGART-AAA-HDGT-----G--PAGADRDAEGERLRARLAEA----SDDEERAVLLDLVRDCAADILGHDQVGPEDNLAEIGFSS
FSALQLCTRLNAATQLTMPTVVVYDHPTPAGLALHMHGRLA---------
>tr|A0A0B6VLR1|A0A0B6VLR1_9ACTN Putative type I polyketide synthase OS=Streptomyces versipellis GN=vstA5 PE=4 SV=1
--RYEWRWEPARVPAA-AGPPGTWLVVAAPGALEESVVALAARGGRVVPLVVDPE------------SSGGGESVSVLRAGLRARPEVDGVLSLLALSER
RHPA-----FSAVTAGLAATVELLDALDDMGVRAPVWLATRGAVSVSSADVAGPAAAQVWGLGQGPADGGAGRWTGLVDLPGVPDG---RVADRLVDVLA
GSRADDRVAVRGPGVFVRRLVRAPGEGG--A---GAELGGTALVSGAASVLGGQVARWLAGRGARRLLLAGAREAEAPEV------VKLSAELGDLGAEV
TVAVCDPADRAALAGVLAGVPD--GAPLTAVVHVGAAGEAGGVRA--LERMDRALVRDVAAVAHLDELTGGADLRVFTVFSSPSGLPGYGG---GSVAEA
CVEALVRGRR-ARGLPGLSVLSGPLEE-------EPTEQVPGVGGV---PASAVPVLAGAAERAQPVVVADVDWPSLVALLGA-----------------
-EG----GRPFE-KVPEVRR-LL--RGGP-----D---------AGAGRVSARLDGV----PAEERMGVLLDIIRTDVAELLGHEGIGADEDFTDLGLSS
FSALELTNRLRA-AGVEVTPNVIFEYATAARLARRLVDGAG---------
>tr|I0J6Y4|I0J6Y4_SORCE Non-ribosomal peptide synthetase/polyketide synthase OS=Sorangium cellulosum GN=pelA PE=4 SV=1
--LHEVAWRPAEPLAEPLPRGGAWVVLADQGGVGAALHARLALGQRCVRVFAGAGYERIEPDLYRIHPARAADYQRLLREVFGEEGRCLGAVHLFGLDAA
PAPATPETLSADLTRGSVSAAHLTQAIVRHRDAPRLFLVTRGAQATLGGARVSAAQAPIWGLGKTIALEHPGLKCTRIDLDPAATD---ADAALLARELG
ARDREDQIALRGEGRYLGRVVRGRFEA-GAGTPFALRSDVSYLVTGGLGRLGLALSRWMVEAGARHLVLVGRRGPGDAAR---GGLEAL----QAAGARV
LVAQADVAARGDVARVLSTIELE-MPPLGGVIHAAGVADDHPLLDLDEERFRRVFAPKALGAWNLHALTEGRPLDFFVMCSSSASLFGAPGEASSSAADA
FLDALAQERH-AMGLPAMSVQWGAFAEGGPEATAARRERRPRRGVAPLTLEQGLEALRRLFARPRAAVVVRFDARQWMELYPGA----------------
------ASLPLFVEL------------A-------REAASVGG-QEAPQIRGTLGRA----APRERPFVLERHVIEQVSRVLRVARVDAHAPFKDLGLDS
MMSLDVRNRLEASLGVQFSATILFTYPSTAALARYLLDRMDIPA------
>tr|A0A0C5FUT4|A0A0C5FUT4_9ACTN Uncharacterized protein OS=Streptomyces cyaneogriseus subsp. noncyanogenus GN=TU94_22470 PE=4 SV=1
--LEHRAVVLAAPWVEVRPADALWQRVDVLWAVMVSLAALWSFAAACVAGEDGARVVAVAPVDYASHSAQDALADDLLRELADIAPRSSGRLDTVGLDAG
YDVARPVAVVGSLRREDLADLATVLTLAAWRTEAPLWLLTRGAAGVTDEEAVRPEAAQVWALGQVAGLELAGAWGGLVDVPEEWDE---AVATGLADVLA
AGEGEDQVAVRASG-VFGRRLVRAPLA-GTAPSRSWSPRGTVLVTGGTGGLGAHLARWLAKEGAERLLLLSRSGERAEGA---TELREI----EASGTAV
ELVACDVTDRDALAGVIGAVPAE--QPLTAVFHTAGAAAHGPLTELDPAALDEQLAARVAGARHLDELTAGVELDTFAVFSSGAAVWGSAGNGANAAAGG
YLDGLARRRR-ARGLAAVSVSFSGWQGTALARGAQ----LSRRGVRLLPPELAGQALRQVLETDETSVVADMDWSLFAPGYTLA----------------
------RRRPLIEDI------------P-------EVEAAQDG-SAGAELRARLAGL----TEAERRSHLLGLVRGEAAQVLHAAEVTPARPFRDLGFDS
LTAMELRNRLNRATGLRLPATLVFDHPSPQRITEHVLAELGKDG------
>tr|B2HJA3|B2HJA3_MYCMM Polyketide synthase PKS OS=Mycobacterium marinum (strain ATCC BAA-535 / M) GN=MMAR_0101 PE=4 SV=1
-----------------------------------------------------------------------------------------GTVVIWESCCA
A----DDDVVRSAYAATHAALAVLQSWLSGDRPGTLVIVTHGGVALTDEGVKDLAAAAVWGLVRSAQSEHPG-RIVLIDTDSAPTDP---EVLMDLA-NL
AGRGEPQLLVSGGAVYGARLAPIPPALSAAELASVLDPAGTVLITGGTGMAGGVLARHVVGGGVRHVVLASRQGEQAPGV--AELVSE----LSAAGAEV
LVLACDVADRDAVAQMMEQVRR-RCPPLTGVIHAAGVLDDTVIASLTPDRMNPVLRAKVDGAWHLHQLTRGLGLSMFVLCSSIAGVMGSPGQGNYAAANT
FLDALAAHRR-ATGLAGLSVQWGLWEQTSAMTGHLDLARIRRSGLAPMSVGQAVELFDAAVLLDRSTVVACLDRNALASPAVSA----------------
------ELPMLF-------HSLL-PR-PS------RRVINKDATTHESGLAQRLQAL----SPHQQHQLLVETVRNQAAVVLGRQDIDPECTFQDLGLDS
LTAVELRNRLKAASGLSLSPTLIFDYPTPATLARHLAQQLIGT-------
>tr|A0A0C2BAZ7|A0A0C2BAZ7_9ACTN Uncharacterized protein OS=Streptomyces sp. 150FB GN=QR77_00870 PE=4 SV=1
-----------------------------------------------------------------------------------------AVVVATGVSAT
D----GSDIASAAHRTATWALKLVQDWLKEESLSRLVIVTSGAIVTTDADTAALAYAPVWGLVRSAQTENPG-RFALIDMDEHPAS------RQVLT-HV
VASGEPQTAVRKGVAYVPALVRAPAPV---DTRRRLNPEGTVLITGGSGSLGVLFARHLVVHGVRHLLLAGRRGAAAPGT--AELCLE----LAELGAQV
TVAACDVADRTALVALLAGVPE-A-HPLTGVVHTAGVLDDGVIPALTPERLDRVLRPKADAALALHELTRDLDLAVFALFSSVAGVFGSGGQGNYAAANS
VLDALARHRR-DLGLSGTSMAWGPWQQSGGMTADLDLRRMARAGFVPLTAEEGLALFDTAIGGPDAVLVARLDHAAFGAAAAPG----------------
------AP--LS---------RV-PG-RESV--RRIAAAAD-EPDGDDSPRRRLAAA----PAEARVGLLLAEVRTEAAASLGHAAIEPDRPLAELGLDS
LAAVELRNRLATVTGLSLPTTLLFDYPTPRAVAEHLEELWSRE-------
>tr|A0A0F2TC25|A0A0F2TC25_9ACTN Uncharacterized protein OS=Streptomyces rubellomurinus GN=VM95_28095 PE=4 SV=1
-----------------------------------------------------------------------------------------AVLHTWSAEPF
E----PEGLLEPVDRICAPVLHLVQAGPSGPGLPRLLLATRGAQRVGERALPAVAQAALWGLARVIVLEHGELRPAVVDLDPDRPAE---SAAALLGEAL
RPAGEAQLVLRGERRLAPRLERHSAPRPVPPQDGPVRAAASYLITGGLGALGLETARYLVDQGARHLVLVGRQKPSAQAE--S---AE----LRERQATV
LVRSADVSRPEDVTRVLADLDA-ALPPLAGIVHAAGFLDDALLLGLDRDRLRSVAEPKASGAWQLHRATAGRELDFFVMFSSAAALLGSPSQGNYAAANA
YLDALAQYRQ-ARGLPALSIDWGPWARIGLAAGPE---ALAAQGVLALEPRQGIEALDHLLRAGSAQACVPLDHGRLREAADAG----------------
------LLPALL-------TGLL-AA----------EPAAAVPGGPPPELRGRLAVE----PGRRRRAILAEHCRAVVAKVLKT-RIDPTEPLAAMGLDS
LMSLELRKRLEGSLHTDLPATIGWRFPTVDALVPFLAERMGIA-------
>tr|U5DKA0|U5DKA0_9CHRO Polyketide synthase module OS=Rubidibacter lacunae KORDI 51-2 GN=KR51_00012640 PE=4 SV=1
------------------KPIGDWVIFADTDGIARNLAERHADGETCTLVYRDTPPDPTDISTLQLDPQDPGSTDRLLDRLQERGAGLQGIVHCWGLDAP
VAEMDAPALAAASRLGCGTVLTLVQALIRGLSAPRLWLVTRAAQPAGESLLSGVSQASLWGMGKAIALEHPELRCSRIDLDANLAIS--AQAGQLWAEVR
SGDPEDQVALRQDHRFVARLVRNQLEKPPPPAELSLSSEGTYLITGGLGGLGLLVAEWLVKHQVRHLALVSRRGSDA---TVQAKLAL----LEERGAKV
DVIQADVTDEDAMAAALERIRRSP-WPLKGIIHSAGALDDGTLQQQTWEKFATVLGPKVQGAWILHRLTQPDPLDFFVSFSSAASLLGSAGQANHSAANA
FLDGLAHYRQ-SVGLPGQSFQLGIVGQVGEAAERGADRRGERQGMGSINPQQVLVALEGVLRQEIPQVLAAIDWTTAARL---------------SPQWR
A-------WPYLADFA---------ASGA--------EMSPEGDTAIASFVQQLQQ----APAPEQRALLATFVRQQVAQVLGMAAIDAEAGFFDLGMDS
LTAVELRNRLQTGLGISIAATSLMDYPTLAALLEFLADRLL---------
>tr|Q847C6|Q847C6_NODSP NdaC OS=Nodularia spumigena GN=ndaC PE=4 SV=1
------------------DLSGDWLIVTDN-NLPLAIQAHIKDHSSCAIASPENSS---ELETWL-----------------ANSPSPRGIIYLVSD---
----RHHQPESILCDRCSYLLNLLQAIQ--PNPPKLFLVTAGGQPFGLEKPSFLTQSPLWALGRVIALEEPELWGGMIDLDPNADMA--QNLAALLPALT
NSAREDHLLFRNEQAYVARLV--------PPKPVTIQAQATYLITGGIGHLGLELARHLVDLGAKNLILTTRRQFPPRTSAIIQTLIT----LEAHGASV
EICQADVGDFQQMSDIFENIQKTS-SPLRGIFHLAGVSGRARLSECTFDDIEDVFQAKVRGSWNLHQLSLKTELDYLVFFSSAGAIWGAKEQGLYDAASH
FMDALAHLRS-RQGLPATSLNWALLAGNGIVSPEYE-DWLKQIGMKEIALEPAFRAMNAIMA-GKTQVLADVDWVRFKNI---------------YQFHG
N-------KPLLEQLG---------ELPI--------PVKS--EKASSSSRRFIEE----QPPGERREHLFAYIGKQVATILGIKMPDPDQGFLAMGIDS
LLSIELKNRLEKGLEVSLPASLIFDFPNITRLVDYLVEQVF---------
>tr|A0A0D6YGA9|A0A0D6YGA9_MASLA Beta-ketoacyl synthase OS=Mastigocladus laminosus UU774 GN=SP67_20895 PE=4 SV=1
------------------DISGNWLICTD-RNLALAIQEESKHYGYCAIANP-NSS---ELETWV-----------------ATSPSPRGIIYLLNAD--
----HSNQYESTLFNRCSYFLNLLQAIK--PSPPKLFLVTQGGQPFGLERPSFMTQSPLWAMGRVIALEEPELWGGMIDLDPHADIA--QNTTFLFSGLI
NSVTEDHLLFRNSQTYVARLV--------ATKPVIIQSQATYLITGGIGHLGLQLAHHLVDLGAKHLILTTRRQFPSKAAEIIQNLKI----LEQKGVSV
EVYQADVGNFEQMSRIFTNIQKTS-YPLRGIFHLAGISGRARLSDCTLDDLKEIFQAKVRGSWNLHQLSLETQLDYFVLFSSAGAIWGAKEQGLYDTVNH
QMDALAYLRH-LQGLPATTLNWALLAGNGIVSQDYE-DWLKQIGMNEIPLDKAFQAMDTIMA-DKTQILADVDWIQFKNI---------------YQFQG
N-------KPLIEKLG---------KSPT--------PIKP--VKKSKSQRSFLEN----VPPTERREHLLEYIGKEVAKILGIKIPNPEQGFIEMGIDS
LLSIEFKNRLEKGLEIALPSTLIFDFPNIRKLNNYLFEQIY---------
>tr|U5TVV1|U5TVV1_9NOSO McyG OS=Nostoc sp. 152 GN=mcyG PE=4 SV=1
------------------DIAGDWLIVTDS-NLALAIQEEIKHHSSCAIANPEHSL---ELDT-----------------------SLHGIIYLVGD---
----RNEPSESILFNRCRYFLNLLQAIK--PNPPKLFLVTQGGQPFKVNQPSFVNQSPLWALGRVAALEEPALWGGMIDLDPHADIA--QNIAALLPALT
NSAKEDHILFRNHQAYVARLV--------PTKPVTIQAQATYLITGGIGHLGLQLAHHLVDLGAKNLILTTRRKFPPRTSEIIQNIIN----LEKKGASV
EICQADVGDFPQMSDIFERIQKTS-YPLRGVFHLAGVSGRARLSECTAADIAEVFQAKVRGSWNLHQLSLGIELDYFVFFSSAGAIWGAKEQGLYDAASH
SMDDLAYLRR-LQGLPATTLNWALLAGNGIVSPEYE-DWLKQIGMEEIALNKAFGAMDAVIT-GEIQVLADVDWVRFKNI---------------YQFNG
K-------KPLLEKLG---------KAQV--------SVK-----ESSSSRRFIEE----VPPGERREHLFEYVGKQVSTILGIKISEPDQGFLEMGIDS
LLSIELKNRLEKGLEVSLPASLIFDFPNITRLVDYLVEQVF---------
>tr|Q7WRJ0|Q7WRJ0_9NOST Peptide synthetase polyketide synthase fusion protein OS=Anabaena sp. 90 GN=mcyG PE=4 SV=1
------------------DISGNWLIFTDSENLALAIQQQSKDCGSCAIANLENSS---ELETRL-----------------ASSLCWRGIIYLVNGG--
----EGDQYESTLFNRCHHLLNLLQAIK--PHPPKLFLVTQGGQPFRLEQPSFVTQSPLWALGRVMGLEEPELWGGMIDLCPHADIA--QNLVALLSGLT
NSVTEDHLMFRKGQAYVARLS--------PTKPVTIQAQATYLITGGIGHLGLQLARHLVDLGAKHLILTTRRQFPLRAGEIIQNIKT----LEQKGATV
EVCQADVGDFEQMSRIFTKIQKIS-DPLRGIFHLAGVSGRAKLSECTLDDIAEVFQAKVRGSWNLHQLSLATQLDYFVLFSTAGAIWGAKEQGLYDTASH
FMDALAHLRH-LQKLPATSLNWALLAGNGIVSQDYE-DWLKQIGMKEIALDKAFAAMTAVME-GKTQILADVDWVRFKNI---------------YQSKG
N-------KPIFEKLG---------EYQN--------SVKG--IQQSISTRRFLEE----IPPGERRQHLFEYIGKQVGTILGNKIPDTEQGFLEMGIDS
LLSIELKNRLEKGLEVALPASLIFDFPNIRRLVDYLVEQVF---------
>tr|A0A014MT90|A0A014MT90_9ACTN Uncharacterized protein OS=Streptomyces sp. PRh5 GN=Z951_28760 PE=4 SV=1
SWRYRITWSPMAVEGRTAPLSGTWWVAVPEGADGAAVAALDRRGARVVPLTV--------------ATTGRDALAERLRHEAVTGGTPAGVLSLLALDDG
PHPE-----HTALSTGLALNVGLIQALGDAGIAAPLWLATTGAVSVSGSPLGSPAQAATWGLGRVVALEHPQRWGGLVDLPENLDE---RTADRLCAALG
DSGPEDQLALRDAGVFVRRLVRAPLRTP---GRESWKPHGTVLITGGTGGLGAQVARWLARSGAEHLVLTSRRGMAAPG--AAGLRDELIA-LGEGGVRV
TVAACDVRDRDEVAALLRRITTG-GDPVHAVFHAAGVVEFSQLADSTVADFAEMADGKVLGAAHLDALLDQDHLEAFVLFSSIAATWGSGGQSAYAAANA
HLDALAEHRE-ARGLPATSVAWGPWADHGMIEHGEVAEHLSRRGLPAMAPELAVAALSEALHTGETSVLADVRWDRFVPGF------------------T
AARPR----PLIGELPE---------VRDALAT-TAAPDTTGPDDVADTFLASLADL----TGEDLDRALRDLVHAQAAAVLGHDAVAGGRPFKELGFDS
LTAVELRNRLAAVTGLDLPATLVFDYPAPAPLAEYLRGELP---------
>tr|D9W7F8|D9W7F8_9ACTN Modular polyketide synthase (Fragment) OS=Streptomyces himastatinicus ATCC 53653 GN=SSOG_08452 PE=4 SV=1
SWRYRIAWDRLHDTVGAPALTGTWLLLVPSGAEHPAAAQLDAHGAARETLTV--------------DTAHREALAQQLT---DVRTAPVGVLSLLALEES
HHPD-----HPAVPTGLAATMALVQALDELGWPAALWCLTQGAVAAAPSALPHPHQAQIWGFGRVAALEYPQLWGGLIDLPDTLDA---RTPGRIAG--T
PGQPEDQVAIRS-AVLGRRLEHAPATDA---LAVPWQPTGTTLITGGTGGLGAHLARWLARNGAPHLHLISRAGPDAPG--ATELTQELTE-LG---TTV
TITVCDVSDPTALHHLIDTIP-A-EHPLTTVIHAAGIAENTSLGEIDLPHINAVLQPKALAATHLHELTKDHDLSAFVLFSSGAASWGGSRQAAYAAANT
YLDALAEHRR-LQGLPATSIAWAPWGDAGMAADEAVIEYYNRRGMNPLDPDLAVASLQHALDHDDITTVADIDWEKFPVSF------------------T
AQRPS----PLLTRLMP---------TPSSG---ADAPDSTAA---ISSLQQQLAGS----TPAQQHQLLLHHLQSHAAAILGYHSIPPAQPFQELGFDS
LTAVEFGNRLTATTGIDLPPTLIFDHPTTNQLADVLRGRLV---------
>tr|A0A0A8ELH0|A0A0A8ELH0_9ACTN Beta-ketoacyl synthase OS=Streptomyces sp. 769 GN=GZL_03711 PE=4 SV=1
SNG-ATTWTRHASGQPVPVVPGAWDDLAAAGGYGPGLRALHAAGS--GAVRV--------------RIAGRDAVSLTVSDQATVPTSPGGLPELVFVAAS
GHPG-----ASVAHAAVHRALAMVQELEERFASSRLVVLTRGAVATGADDVADLGGAAVWGLLRAAQSEHPGRFV-LVDLD----E---HAASRGL--LA
AASGEPQLAVRQGALYAPRLARVPPAEG---IRRPLDPAGTVLITGATGALGGHVARHLVAHGVRHLLLTSRRGEAAAG--AAELVSELAE-LG---ASA
RMAACDVADRDELAALLDGVP-E-AHPLTAVVHAAGVLDDGVLESLTPERIDAVLRPKVDAALHLHELTRDLDLAGFVLFSSASATFGSAGQGNYAAANA
FLDALAVRRR-ALGLPAVALAWGPWAD-GGMADEADRARMARLGMVPLSADQGLALLDAAQSVDEAVVPIRLDTAALRT---------------------
KAGGV----PALRGLIR------------------SSARPTVSTTEGPSLRERLAAL----TDAEQDRLLLDLVRTHSAAALGHHAVDAGRGFLELGFDS
LTAVELRNGLSAATGLRLPATLLFDYPTPSALRDHLRAELA---------
>tr|A0A0A8EKF4|A0A0A8EKF4_9ACTN Beta-ketoacyl synthase OS=Streptomyces sp. 769 GN=GZL_03708 PE=4 SV=1
SRGEDQPWTRHASGAPTSGLGGVWQRLVESGGYGPGLRALHGHGA--SALRV--------------RISGQDAVSVLVADGAELRTGPTDVPELVLVT--
------------VRAATHRALELVQRLDERFGASRLVLMTRGAVATGADELSDLAGAAVWGLIRSAQSEHPDRFV-LVDTD----G---RAVSHQA--LA
LATGEPQLAVRKGAVLGARLARVQPVQD---AAPKLDPAGTALVTGATGTLGRLVSRHLVAYGVRRLLLTSRRGEAAPG--ARELVAELAE-LG---AEA
RVVACDVADRDALAALLAEVP-A-EHPLTAVVHTAGVLDDGVLEGLTPERIDTVLRPKVDAALNLHELTGDTDLAMFALFSSAAATMGSAGQANYAAANA
FLDALARHRA-DQGRPAVSLAWGLWAQAGGMAGDTDLTRMQRSGVGGLTPELGLALFDAAHTLAEPAVPISLDIDAVR----------------------
--APV----PALRGLIR------------------GATRPSAVATEGPSLRERLAGL----TVAEREAVLLDVVRAHAATVLGHQAVEEDKTFGDLGFDS
LTAVELRNGLTAATGLRLPATLIFDYPTPAALADYLLTELP---------
>tr|A0A0F4K569|A0A0F4K569_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. NRRL B-1568 GN=VR41_13920 PE=4 SV=1
SWRYREVWNPLGSTSS-AAPSGTWLVLAPTAGVDDAWIAAGALGQAVRIDVDAS--------------SDRTQLAGLLAEATADGAQFDGVLSLLALDDA
PQ-------AAGTSAGLLGTVVLLQALSDAGITAPVWAVTRGAVCAVSEPPASPEQAAVWGLGRVAGLERPERWGGLVDLPEMLDEQ----AVRRFAVLA
GIGEEDQVAVRASGILGRRLVPAPAEE----NTGRWEPAGTVMVTGGTGALGAHVARWLARHGAPHLLLLSRRGPQAPG------AAELEAELSALGTRV
TITACDVADRDALAAVLAAVPAEH--PLTGVVHAAGVLDDGVLDGLSAERFETVLRAKVASARLLDELTRDLDLSVFALFSSVVGSVGNSGQANYAAANA
ALDALAARRR-ALGLPATSIAWGPWTGDGMADRA--RAAGARISTAVLDPESAMSALAQAVNEPAPTTLLGLRPSRLLAEIPE-----------------
-------ARRILDRLV---E---------------ARRESASA---TQQLRKQLRE----GTEAERLALLLGMVRARAAAVLGHHAIGGDKAFRDYGFDS
LTAVELRNQLAGATGLSLPTSLVFDYPTPRALAAHLVAEL----------
>tr|X8B2N2|X8B2N2_MYCAV Short chain dehydrogenase family protein OS=Mycobacterium avium subsp. avium 2285 (R) GN=I549_4773 PE=4 SV=1
EDRYEIRWEKSTV-PG-PEAEATWLVVGDDDAVAPLV-ALTARGHHRILVLPSD--------------ADEERLEIVLRAAAAEEAPLRILVAALDSGTA
PS-------MRMQHRVLAGTRRLFRAAAAAELRQPIWLVTRGAQRVTDADTVFPDQSCLWGFGRAASLEYPQLWGGLADLAQGSAEE----WSRLASPRD
PAVGEDQIALRGSDIYVPRLTRRSGQA----AALTLRADATYLVTGGLGSIGLEIAGHLAAQGARHLVLTGRRAPGEAA------QRRIDALSQQHGCEV
RVIAADVADAHHVARLLGAVRAELP-PVAGIVHAAGEIGTTPLSDLEDAEIDRVFAGKVWGAWHLSEAAADLRLDFFVSTSSIASVWGGLGQTAYGAANA
FLDGLAWRLR-EQGVNGISVNFGPWAAGMADENA--RARLAQRGIKTLSPADALAGLADVMATA---VVARIDWTRFLPQQAG-----------------
-------QRSLLAELA---R---------------EI-PDPSG---KTGLVERLAG----APVQQRRKLMTEFLRNAVAEVT-RAEIREDAGFFDLGMDS
LMAIELRRHIEQGVGKQIPATLAMDYPRLSDVAEYLLGDV----------
>tr|A0A0M8VZC5|A0A0M8VZC5_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. NRRL WC-3618 GN=ADL01_17420 PE=4 SV=1
GWRYRVTWKPLANGARAGALSGTWLVVVPEEAAAHVSEALTQAGASVVQLGFAEA----EL--------DRKGLVEHAQ-SAVGAAEPAGVVSLLALAEH
PHP-----AHPVLPTGLAATVALVQALDDAEIGARLWAVSMGAVSTGRSDLVSAAQAQLWGLGRVVALEHPERWGGLIDLPQTPDSRTATRLATALAGIT
GTGFEDQVAVRGSGLFVRRLTHAPLVTH---PSRTWTPRGTALITGGTGALGAHVARWLVREGVEHLVLTSRRGLDAPGA------GELKAELEELGAEV
TITACNIADRDAVAGLLDELAAG-GHTLRSVFHAAGVSPALPLADTAPADLADALDAKAAGAAHLDALLGDTELDAFVLFSSIAAVWGSGGQSGYAAANA
FLDAIAERRR-ARGQAATSVAWGAWGGSGMAATAEAEEHLRRRGVALLGPDLAIGALAQALTYDETCLVADVDWERFAPT------------------FT
AAR----PSAFLGGLPEL-RPQR----RQS--TSAP----AGGGEPVSEWASRLTGL----PEGERQRLVLDLVRTEAAAALGYDAVEPTRAFRELGFDS
LTAVELRNRLTAATEVSLSATVVFDHPSPEVLARHLLAEL----------
>tr|A0A0F2T3T2|A0A0F2T3T2_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces rubellomurinus GN=VM95_37040 PE=4 SV=1
DWRYRIAWKPLADRPA-AALTGTWLVVVPAGRTEDAVRALDGHGARTVLLETTGA----DA--------DRAVLAERLR-PLVDGTDLAGVLSFLALDDK
RLD-----GHRSLTACVGLTLVLVQAMGDLGLRIPLWCATHRAVATGPSDPADQVQAQLWGLGRVVALEQPHLWGGLVDLPAEPDARALGRLAGVL---A
GAGDEDQVAVRPAGLFARRMVHAPLGG-----VRDWRPGGTVIVTGGTGSLGPRLARWLAERGAEHLVLASRSGPDAPGA------ADLAAELTATGVEV
TLAACDVADRDAVAALLDGLRAE-GRTVRAVVHTAAFIELLPVDGTPLESLDQVLAAKVDGTRHLAELLDPEALDAFVLFSSIAGFWGSGDHAAYAAANA
ALDALAEAGR-ARGLPMTSVAWGVWEDAGDQDVERTRRKVQAQGLPLMRAELAVAALQQSLDHDDTFVIADIDWARFVPL------------------FT
ALR----PSPLLTDLPEA-RAVL----AAP--EAGG----APGAGNDSELRRVLVEL----SEADQLRTLTELVSAHAAAVLGREAIKPERAFKELGFES
LTAVELRNRLNAATGLRLPATLVFDYPTPAALAAELRREV----------
>tr|A0A014KX15|A0A014KX15_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. PRh5 GN=Z951_46615 PE=4 SV=1
SWRYRATWQQLPDPA-APALTGTWLVVVPAGQEEHTLQALRAHGATALPYAVDAH----HI--------DRATFRERLD-QVTEESQPTGVISLLALDTE
PLA-----GHSAVSAGLGATTALLQALDDAGISAPLWCVTQGAVATGRSDLPHPEQSPIWGFGRVAALEHPQRWGGLIDLPAAMTHHTAGRLAALL---A
PGQPEDQVAIRTTGTYARRLTRVPAANT---APAPWEPSGTTLITGGTGGLGAQVARWLADRGAPRLHLVSRSGPDAPGA------SELSEELTALGTDV
TITACDVSDRAALRRLIDSVPA--EHPLTVVIHTAGTMELGQIGELDPGRLQPVLRSKALAAAHLHDLTQDLDLTAFVLFSSNAATWGSGQQAAYAAANT
YLDALAEHRR-ARGLPATSLAWGPWGEAGMAADQHTLSHLERRGLSPLPTDLAIASLQHALTHDDTAVIADVDWERFGRT------------------FT
AQR----PSPFLTRLMPS-SAEP----ATS--TA--------IAADDNPLRQQLSAA----PAAQRHQLLVRHVQTLAATILGHDAVPPGQPFQELGFDS
LTAVELRNQLASTTGLALAPALVFDHPTPNALATYLGAEL----------
>tr|K1V3E7|K1V3E7_9ACTN Polyketide synthase family protein (Fragment) OS=Streptomyces sp. SM8 GN=SM8_03688 PE=4 SV=1
GWRYRVTWQPVPLGND-DGTGRPWLVLTPAGHDDALAATF---GEHAVRLAVPAD----ED--------GTAAL---LD-GAADGTAYAGVLSLL-----
-T------D------GTARPDTLLRLLA---IDAPLWCVTRDAVSVGRSDAADPDRAALWGLGRVLALDEPERWGGLVDVDHVADARTVDRLRAVLTAAT
DGPAEDQVALRASGAFGRRLSRAAAPA----PDITWHPAGTVLVTGRAEGFGGHVARWLAAHGATGVLLAGPAGPEDVAT------TALRAEVEALGATL
TVVRHSPADAAPLTEALA-AQTD-DRPLTAVFHTGDTGEETP------G-----VTGARAAYEALTTAVGDRDLDAFVVFGSISAVWGVGGQGAGAAAGV
CLDALVQRHR-AHGTNAVSVSWGAWQGA---GPDGLAAHLRANGLPAMEPARALDALAPAIGEAPASVVADVAWDRFAPA------------------FT
RTR----AGLLLTGVPEA-REAL----STT--GGDA------DAGTASALRERLRQS----DPSERPRTLLDTVLTEIASVLGHAAVPAENAFNDLGFDS
LTAVDLRNRLTTATGLTLPATLVFDYPTPAALAAHLLTEL----------
>tr|Q1PCG2|Q1PCG2_9ACTN Polyketide synthase I protein (Fragment) OS=Streptomyces sp. 98-62 PE=4 SV=1
GYDYGPAFQGLRAVWGDAALHADGLRTAPPGTDGP--VSLYASGATALRVRIRGG----DT--------LSLDLAAAVEALVSRPVDPAALTSPVVLDER
GTA-----AADAVPDATGRVLAVRDWLADERRGARLVVLTGGAVATGTED-TDLAGAAVWGLVRAAQGEHPDRFVLVDSVAHDGGGESAS-GPGVFAT-A
AASGEPQLALREGTVRVPRLARAAVTGA---FGPAPDPHGTVLITGGTGVLGAVVARHLATHGVRRLVLAGRSGTAFDDF----------GDLAERGTEV
VVARCDAAERDQLAALLADMPA--ERPLTAVIHLAGVLDDGLVTDQTPGRLDAVLRPKADAAWNLHELTRDLDLSAFVLFSSAAGTIDGAGQSGYAAANA
FLDGLAAHRA-AQGLPALSLAWGFWEQR---LTDADVERMARAGVRPLPTEEGLRLLDAALAADVPLLPVGLDPRALPPVL----------------ARS
GAR----ARPSYGGLPRH-R---------------------------RSAAERLAAL----GAAEREAALTELVRTHVAAVLGHMVLDPRRSFREAGFDS
LTAVELRNRLGNAVGLRLPATLVFDHPDAEALVRYLKTEL----------
>tr|U5QR00|U5QR00_9ACTN EbeG OS=Streptomyces aburaviensis GN=ebeG PE=4 SV=1
GWRYVIDWQPLREPSG-PALTGTWLLATPAGHTGDAERALAEHGARVLRIELDPA----GD--------RAGLAARLRE-LAAGHEPFAGVLALLAPAGQ
PHP-----EHPALSVGLVLTLALVQALGDAGVGAPLWCATHGAVSVGGADLVSPGQAALWGLGRTVALEHPDRWGGLVDLPGRPDARAGARLCGVL---A
GIADEDQVAVRSGGLYARRLVRAAAPDD---APAHWRPRGTVLLTGATGAVGPYLARWLARGGAEHLVLTSRTGATGPAT------AALRSELAATGTRL
TIAACDVADRSALAALVAGLAAD-GTPVRAVVHAAAFIRLSSLDATTTAEFAEVVAAKADGARHLDEIFDRDELDAFVLFSSVAGVWGSGDHGAYAAANA
YLDALAQQRR-ARGLRATSVAWGLWNTPGPSK--AVESRLFRQGLPLMDPEPAVAALQQVLDRDETFVLVDVAWDRFSPT------------------FA
SAR----PRPLLDAIPEA-RRGR----PAE--RQEE----QA-ADVLSRWRRRLAAL----PAAEADRELLELVAGTVAVVLGHESIATGRPFRELGFES
LASVDLRNRLNAATGLRLPTTVVFDHPTILALAGRLRTEI----------
>tr|A0A0M9Z2R2|A0A0M9Z2R2_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. XY431 GN=ADK60_17650 PE=4 SV=1
SWRYRIGWQPLPDPPAATAAAGTWLVVLPAGHDDDPLLALAEAGATVVTAELTDG----AV--------RRTDLADTLA-TALGDRVPTGVLSLLAAADR
SHP-----DHPALPTGTALTVALVQALGDLALTAPLWCVTAGAVSTGPDDVTHPRQALVWGTGLVAALEQSARWGGLVDLPPDLDARTRTRLAALLTASD
GVGREDQLALRPAGLLARRLRRAPRNDA---RPEHWKPRGTVLLTGGTGAVGPHLARWLARSGATHLVLPGRRGPQAPGA------AALAAELAVLGVRL
TLPVCDLADRRAVAALLTGLEAA-GDRVTAVVHAAAFVALAPLDGTPMSAFEQIVAAKAAGAEHLDALLDR-ELDAFVLFSSIAGVWGSGDHGAYAAANA
YLDALAQHRR-ARGLTATTVDWGIWQAEGED---ADLFKLEQHGLPRIAPDLAVQALRQALDDDETVLVADVDWERFAAV------------------FT
STR----PSPLLTGIPEA-RRAL----AAA--TGDE----AP-AA--ALLRQRLTAL----GESEQHRLLLDLVRTHAAAVLGHDAIRPGAAFQDLGFAS
LTAVELRNRLNTATGLRLPSTLVFDHPSSVALAREIRAEL----------
>tr|V5UVT6|V5UVT6_9DELT Polyketide synthase OS=Jahnella sp. MSr9139 GN=mscA PE=4 SV=1
DLLYELIWEPAETGANGSVARGSWIVLGGEGPTGGELARIRAQGQRCYLITPRAGE--HGAEQRGVDPLDAQGFTDLLRSIE---GPVVGVVHLWAEGPV
AAVLGLDTLTAVEERACGGLLHLVQAMRRVERMPRLWIATRGAQPVGSG-PVRAEQAPVWGLGRALSMEQPDLRCVRVDLDPEAD----EQAERLLGEIA
HPGDENEIAWRAGRRYVHRLARSRARGS--REGVAIDPHATYLVTGGLGALGRRVAGWLCEQGARHLVLTGRRLPEQPLP----DLEQL----SARGCKV
RIVAADVSQPGQVSDLIRQAQA-DGPPLKGVLHLAGSLDDGVLVQQSWERFRRVMAPKVDGTLNLHHATADIALDFFVCFSSIASILGSAGQGNYAAASA
FQDALCHLRR-ATGRPGLSVNWGPWAGSGMAASISDRERIAAQGLQSIEPDVALAALDALLGDAAQQVVLAVDWPAFQRSAPGG----------A-----
-------LPSLVRS----------------FVSREAA-------PARRAWREELE----ATPVATRTLVLQKLIRAEAVKVLGAEAFSDAQPLHELGLDS
LQAIDLQNRFASSLGTTLPFTLVFDNPTIQHITEYLTATL----------
>tr|V5UUZ2|V5UUZ2_SORCE Polyketide synthase OS=Sorangium cellulosum GN=mscA PE=4 SV=1
DLLYELAWEPAEA-APGSVAPGSWIVLGGEAPAGAELARLRAQGHRCYLVTPAKAGQGADVDHHHVDPLDAEGFAALLRGVE---EPVAGVVHLWAADPL
PA-LDLADVTAAQERACGGLLHLVQAIRRAKSMPGVWIATRGAQSLGSG-PVQVAQAPVWGLGRALSVEQPDLPCVRVDLDPGAD----DGVERLLGELA
RQGDEGEILWRAGRRYVHRLARCAARGP--REGAAIDPAATYLVTGGLGALGRRVAGWLFDKGARHLILTSRRAPDEPHP----ALAEL----EARGCEV
RIVAADVAQRGQVEELLAAARA-SMPPIKGVLHLAGALDDGVLLQQSWERFRRVLAPKVDGTLNLHHATLDLPLDFFVCFSSIASVLGSAAQGNYAAANA
FEDALCHLRR-AEGRPGLSINWGPWAGSGMAASVSDRERIAAQGLLGIEPEAALAALDVLLGDAAQRTVLAADWSAFQRAVPGG----------V-----
-------MPPLLSA----------------FASRAAA-------PARRAWRDEIA----VAPAAARQLVLQKLVRAEVVKVLGASELSDNRRLSELGLDS
LQAIDLKNRFGAGLGATLPFTLIFDNPTVQHLTSYLTSTL----------
>tr|A0A0F5A6K6|A0A0F5A6K6_9ACTN Beta-ketoacyl synthase (Fragment) OS=Streptomyces sp. MUSC164 GN=VT50_27135 PE=4 SV=1
NWRYRINWKPVIDQPSEAPITGTWMVVVPPVELAGRIADVERHGARMVRVDLDGTE-----------PE-RSSLADLLRAAQEDTPAIDGVLSLLALDEE
ALA-----EHPGIPRGFAGTVALVQALSDIDIDVPLWLATTGAVSVGRDRVGRVKQSLVWGLGRVVGLEYAQRWGGLVDLPESPDALDERALDRLVGLIG
RSGDEDQVAVRASGVFARRLVRAPLGDAR--PARVWEPRGSVLITGGTGALGGRLARWLAHAGAEHLVLTSRRGLEAPGA------AELRDELTALGTRV
TVAACDAADRGALRELLDGLPAEY--PLTAVVHAAGVLDDGLIDTLTVPRAQGVFRPKVDAVVNLHELTRDLDLSAFILFSSYAGTVGGAGQGSYAAANA
FLDALAQQRR-AQGLAATSVAWGAWGGGGLVDDAT-AAQLKRRGMPPLVPELAVDALQQALDHDEVDIVADVDWERYAPGFAS-----------------
-AR----PRPLLNELPEV-RQAL----E--------AAEAELG-AALTGLAVRLEGL----SAVEREAEVLDLVRSHAAEVIGYEAVEPERAFRDIGFDS
LTAVELRNGLSAAAGVNLPVTMAFDYPTPTVLARFILGEV----------
>tr|H8GEN3|H8GEN3_9PSEU Polyketide synthase family protein OS=Saccharomonospora azurea NA-128 GN=SacazDRAFT_02066 PE=4 SV=1
DKRYGVTWQTLDPA--PAKLTGTWVVVSVVSPWVQGALALARAGATVRHLRLDEAD-----------TD-RAVLAGKLREL---GAEPSGVLSLLAFDER
GHS-----EHPAAPVGLALTVALVQALGDVDVRALLWCASDGAVSVAPEAPRNPGQAQVWGFGRVVGLEHPERWGGLVDLPAT---VEERYQAGLANAVG
NAAEEDQLAVRGRIPLVRRLVRTPLRDAA--PVRSWRPEGTVLVTGGTGALGSHVARWVAREGAEHVLITSRRGMDAPGA------AELRDELTQLGSRV
TIAA---------------LLAEH--PVTAVFHVAAVLDDSLIDSLTVEQIHRVAGVKVGGTLNLHELTADMPLSAFVVFSSFAGTTGGPGQGNYAPGNA
FLDAFAQQRR-AHGLPATSLAWGPWAGGGMAEGDG-GELSRRHGLKDVSPELSLEIMKQALDHDETFVVAEIDWERFFLAFTS-----------------
-SR----ARPFLYGVDDV-QRML----A--------SGASSAK-AAPTELGSRLAQL----SEAEQERELVKIVRDQVATVLGHDRIDVKAAFKDLGFDS
VTAVELRNRLNSVTGLKLPATLIFDFPSAASLVAHLRTEL----------
>tr|A0A0N1H7I1|A0A0N1H7I1_9ACTN 6-deoxyerythronolide-B synthase, 3-oxoacyl-(Acyl-carrier-protein) reductase (Fragment) OS=Actinobacteria bacterium OV450 GN=OV4
ENAVEPVWTRHAEGTLPTTVDGAYELLLERGSLPEQAHDAHAGGAPALRVCIADAE-----------GQ-PVLTVGSLVSRQLGGARPESLFEIAPLPAS
AVASADQHVWGALPEGAAQTLAVVQEWADERAETTLVVATRDAVVVDA-EGIDLAQAPVWGLVRAAQAENPGRIQ-LTDLTASTDD--------LAAVIA
S--GEPESAVRPDGLRIPRLTAVPAPVSQ--GPIALDPAGTVLITGGTGGIGAHLARHLVVHGARHLVLTSRRGPEAEGA------GELAAELGELGAEV
TITA-------NITTLLASIPAEH--PLTGVVHAAGTGDNGLVATMDAGRLDRVLAPKADAAWHLHEQTRHLDLPLFALISSAGGLTLAAGQANYAAANT
FLDALATHRH-AQGLAAQSLAYGLWASTGMGTDTD-VKRMERQGLPPLQPEEALALFDAAYASGRPATPLHVNRTA--LAART-----------------
-DE----LPALLR-------SAT----P--------APQSASG-AGANDLAARLAGK----TEEERDSALLDLARAHVAAVLGHDAIAPDRAFQELGFDS
LSAVDLRNQLKAATGLRLPATLVFDYPNARAVAKYIGESL----------
>tr|A0A0A0NDR0|A0A0A0NDR0_9ACTN Uncharacterized protein OS=Streptomyces rapamycinicus NRRL 5491 GN=M271_04690 PE=4 SV=1
GWRYKAVWKPLASA--ETTLSGTWLVAVPEAVLVAAVLGLAGRGAHVVRVVVGAAD------------G-REAITERLRAAAVEPSGVAGVLSLLGLDES
AHE-----SFEVVPAGLAATVGLVQGLGDAGVVAPLWCGTRGAVSVGRDRLVSPVQTMVWGLGRIVGAEYPQRWGGVVDLPET---MDSRAMARVAGVLA
GAETEDQVAVRGSGVFAKRLVRASAPEAT--DADGWRASGSVLVTGGTGALGGHVARWLARTGAEHLVLTSRRGMEAEGA------AELKAELEGLGARV
TVAACDAADRDALAAVLNGIPREF--PLTAVVHTAGVLDDGVLDALTVSRTAGVLRPKVGAVRNLHELTAGMDLSAFVLFSSAAGTIGGPGQGSYAAGNA
YLDALASQRR-ADGLPATSVAWGAWAGGGLVTGEV-GEQMTRSGMLAMSPELAISALQQALDLDETFLVADIDWTRFEADAV------------------
-------DTPLFRELRNA-RSVT----T--------EKQSTAG-SARAELHDRLEAM----PREKREAALRDLVRAQAADVLAHDAVASDRAFRDLGFDS
LTAVELRNRIGAATGLRLPVSLVFDYPTPMVLARFLHGEM----------
>tr|F1B9Q4|F1B9Q4_SORCE Polyketide synthase OS=Sorangium cellulosum GN=leuB PE=4 SV=1
-------------------EGRAWLLLADATDVGEQLGAMLRHGQRPVVVTRGAEGAAIHGGGLRFDPGSADGFRSLLRALDQHGLRPDGVVHLWSLDAV
KGDDDTSELRYASRHGCQSALFLLQALVEAERPPGLWLVTGGSQAAREDTVDGVAHAGVWGLGRVIAREHPELSCRRIDLDARPG---EADIRALFDEIQ
LRSQEDEVALRGGERYVPRVVRRAEAARVHGPGDALRADGTYVITGAFGGLGLRVAEWMVERGARNLGLLGRRPPGA---EAAQVIERLA----QRGARV
REILVDVAHEGRLASALAELQA-SMPPLRGVVHSVGAIDDGILQNLTWERFERVLAPKVEGAWNLHRLTRGMELDFFVLFSSAVALLSAWGQANHTAANT
FLDALSHHRR-ARGLPALTIDWGAWDQVGAAARPEADQKMRDLGMGTIPPDAGLRVLEQLLSEGAVQGVMPIDWSQFARKLR----------------W-
--------SPLVSEV---LS------------------DTGNEERAEPELLHRLEQ----AGPAQRRALLREHVREQIARVMHLSQISEQRRLFTMGLDS
LMSVELKNNLSTSLGKPLRATLVFDFPTLGALVEHLSELLPGAERPA---
>tr|A0A0M8WYI1|A0A0M8WYI1_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. NRRL B-3648 GN=ADL04_26230 PE=4 SV=1
DWRYEVAWAPTSGTAA-PVDPARWLVLAATGPWAAA---LRERGFAVA-----D--------TW-----------DVADTW-DARPGPDGVLSLLALDEE
PHPD-----HPVLPAGLVRTLDLIRTLDPVTPAVPLWCATSGAVSTSGDPVTSPAQAMAWGTGASAALEFPHGWGGLVDLPAVPDE---ESVNALLVVL-
AGTGEDQVAIRGTRRFAKRLRRKASSGP---AARPWRPRGTVLVTGGTGALGGHVARRLARQGAEHIVLAARRGPDAPGA------AGLRDELEAAGARV
TVAACDVADRDALRDLVERV-----GDIRAVFHTAGVIRETRLADTTPAEFAEVVAAKVAGAANIAELL--PDLDAFVLFSSTAGVWGDGHGAAYAAGNA
FLDALAAQHR-AQGRATTSVAWGIWAEGGMAALESVQRQRTLLGLGELDPGRALDALQDVLDHDVTLVVTEADWAQFARAYTHA----------------
------RPSRLLRDL----------------------PE------AHSRPQAP------RPAPPAGGTDLLGLITTHVAGVLGHERLDPRQAFKDLGFDS
LTAVELRNRLTAALGVRLPPTLVFDHPTPARLAAHLSGESGEQDAPR---
>tr|S5XVC5|S5XVC5_PARAH Polyketide synthase OS=Paracoccus aminophilus JCM 7686 GN=JCM7686_2116 PE=4 SV=1
---------------A-PAWEALWQAQAAAGKT--------------------------------------------------------AVLALRALPET
ADTG-----DPA-AAGAAFCAKLNAAVQSARSGIRVFAVTRGTQMQ---PEAVSHHALVNGLAPVLGLECPAGWGGTIDLAVDALG---SDHLALARFVT
SAGHEDRIAIRDGQLYGARLVPEEI------QSPLPVSDGVHVLTGGLGSIGRTVAADLLACGAKSLLLLGRTAEASKGA------AQALADLRTSGAEI
RYAALDCDDGAAVAALIGGLAA-SGQRIAGIVHAAGALAPAALDGLDADGFAAALRGKYSGAWWLHQATRDMDLDYFATLSSVTAVWGTEGFGAYGAANG
GLETISVARR-AAGLPVACVAYGPWALDDSMADEAARAGFARLGVHAVEAAPGVAAINAALPEGAVSVACALDAKRFVKVMGAH----------------
------RPRALFNAL----------------------LA------DQDTLPSV------EPE---RPRAIAQKLREIVGATLGHSAIREDKGFFDLGLDS
IMAVDMSALLAETFGLKVQVSEIFDNPTISSLAAHLQAQMAGHDGPV---
>tr|R1FXT7|R1FXT7_9PSEU Beta-ketoacyl synthase (Fragment) OS=Amycolatopsis vancoresmycina DSM 44592 GN=H480_33430 PE=4 SV=1
AWRRGEEFAEVELPDQ-PRLPFAWTGVTLHAG--VR---LTRRGADEVTVEPS-----------GAPV---ATVASLVLRP-LPAGGLDGVDDLYDWTES
QAEA-----DE-TGKPVHRVLGLVQEWLAAERPEVLVFVTTGAVAVHD-EAPDPDLAAAWGLVRSAQSEHPGRFAL-LDTDD-PDH-------------P
VIPAESQVAIRNGQSFVPRLARVTA--E---QTPDW-GDGAVLVTGASGVLGGLVARHLARHGVRNLVLLSRRGADAPGA------AELAADLP----DA
VFVAGDAADRDRLAEVLA-A-----HRITAVVHAAGVLDDGVVETLTPERLDAVLRPKAEAARHLDELTT--GLAAFVLFSAAAGTTGGSGQGNYAAANA
YLDALAQRRR-AAGQPAVSLAWGLWAEASGMTGDRARDRLGRSGVRPLESAQGLALFDRAVTAGPAAVPIALDAAALRRQAAEG----------------
------TVSPLFRGL----------------------FP------PSAR----------------SEEALLDLVRTHVAAVLGHRAIDPGRAFKDLGFDS
LTAVDLRNRLAAATGLRLPATLVFDHPTPAVLAAHLAGRTGR---TA---
>tr|A8CAC5|A8CAC5_9ACTN Polyketide synthase (Fragment) OS=Streptomyces eurythermus GN=angI PE=4 SV=1
AWRYKVVWKGLPTEET-ARLSGRWLLVLPEGDPGDT---LTRCGADLARVSTAD--------RAHFAELLAAHRRQDEESG-NGEPAVRGVLSLLAL---
----------SHAPSAVASSVPLVQAANDVGLGAPVWAVTQGAVAVIP-EVPDDMGARLRAFGRVAALELPEVWGGSIDLPSAPPD---ERVLRRMVTVL
ADGAEDEVAIRSAGVYGRRVVR---PGG---ARTHWRPRGTVLVTGGTGALGGHVARWLAANGAEHLVLTSRRGQDAPGA------AALTAELEARGVRV
TVVACDVSDRAALAALLDDH------PPTAVFHTAGVLADGVIDGLSADGLALVSRPKADAAELLHELTADRDVDAFVLFSSVTGVWGNGGQAAYAAANA
ALDALAERRR-ADGLPAISIAWGLWAGGGMAEGTGE-ESLVRRGIEAMDPVRAVEALQQALDRDDTCTVAAVDWERFAPSTDAV----------------
------RATHLFSTV----------------------PE------AREALDTA------RRQRPARRHRLVELIRDEAAAVLRHDAIGPDRAFKEVGFDS
LTALELRNRVNAATGLSLPTTTAFDYPNPAALADHILSRLAD--LPE---
>tr|A1YBT8|A1YBT8_SORCE JerE OS=Sorangium cellulosum GN=jerE PE=4 SV=1
AWRYRVAWKPLAIDAR-SDLSGVWLFLAPPDAKDRA---LAESGATVVPVLDVD--------RALLSAR--LREQ-----V-GDGGAIRGVISLLALDET
SLPQ-----HDGLPRGLAFTLALVQALGDTAIAAPLWLLTRGAVSVGRDRLERPLQALTWGLGRVVALEHPERWGGLIDLAGALDE---KALKRLVAALG
GRDAEDQLALRPSGLFARRLVRAPLEAT---AVRAWKARGTALVTGGTGDLGAHVARWLAQNGAEHLVLTSRRGQDAPGA------AELTAELTALGARV
TIAACDSSDRQALAALLQRLRA-EGPPLRAVVHAAGVDQVTPLARTSLAEFAGIASGKVAGARHLDDLLGNAPLDAFILFSSVAGVWGSGFQGAYAAANA
FLDALAEQRR-ALGSTATSIAWGLWGGKSMADDAAK-DHLSKRGVSPMPPQLAIAALQRALDHDETTTLADVNWSRFAPAFAAA----------------
------RPRPLLHDL----------------------PE------ARSALESP------SPAPR-RVRHLVSLVLAETAVVLGHSRLDPHTGFADLGLDS
LMAVEMRRRLQQATGVSLPATLTFDHPSPHHIATFLLDEVFADEAIA---
>tr|K0K5J3|K0K5J3_SACES Putative polyketide synthase OS=Saccharothrix espanaensis (strain ATCC 51144 / DSM 44229 / JCM 9112 / NBRC 15066 / NRRL 15764) 
GWRSDVRHAEIALPAR-PRVPFAWAGVEVLDA--AR---LTPRPDGTVALLAG-----------GRPV---ATVDALTLRP-LTRPGPDGL---HDWRPV
PVPD-----RPADRNPVHATLARLQRWLADDRPGPLVVHTRGAIAA-G-PPIDPAQAPVWGLVRSAQAEHPDRFVL-VDGDGDPRL-------------A
AGTGRPQVAIRAGALLVPRLTRAPG--D---TPPSW-SAGTVLVTGATGALGAALVRHLVDHGARDVVLLSRRGPDAPGA------ADLAGP------GV
RLLAVDVTDRDALARVVADL-----PDLRAVVHLAGVSDDRVLTDLTPEHLDTALGPKADAAWHLHDLTRDRDLTAFVLYSSLAGVLGTAGQANYAAANT
ALDALAAHRA-AAGLPAVSIAWGLWEADSALSATADLARLERVGVRALSTSDGMALFDLAVAGTDPAAAARLDLA------AAG----------------
------APGPATPGV----------------------LR------TAAA----------------RVRALRDLVRAEAAAVLGHAGIADRKPFRDQGFDS
LTAVELRNRVAAATGVRLPATVVFDHPDLAAFVAHLDRELAG---AA---
>tr|B4VAJ6|B4VAJ6_9ACTN Polyketide synthase subunit (Fragment) OS=Streptomyces sp. Mg1 GN=SSAG_04835 PE=4 SV=1
GLSYEVTWKSLSLPES-VRLDGRWLLVVPEHDADHA---LTTHGATVSHLTATD--------RADLSAR--LTTT----AA-EEQEPLGGILSLLGWAEG
AQVD-----RPTVPIAIATSLALVQAVGDAGFGVPVWAVTRGAVSVVP-EVPETAGAQLWALGRVAALELPDRWGGLIDLPADADA---RTAGL---AVR
IAAGEDQLAVRPSGAYGRRVVQAGHPTG---AKPEWRPRGTVLVTGGMGAIGTRVARWLARNGAEHLVLTGRRGAGTPGA------DELAGELRASGVQV
SLAACDVSDRAALAALIDAH------PPTAVFHTAGVLNDGTVDTLTPGRLDGVLGPKATAAVHLHELTAHLDLDAFVLFASVTGVWGNGGQAAYAMANA
ALDALAEQRR-AGGLAATSISWGLWGGGGMAEGNGE-VSLNRRGIRALEPATGIEALQRTLDQDATCTVVDVDWSEFTPRTAAL----------------
------RRGRLFADL----------------------PE------ARRALGSE------GAAQEGQRRILVELVRAEAAAVLRHELLAPRRSFKDAGFDS
LTALELRNRLSTASGVVLPVTVVFDHPNPGALADFLYGEALGDQADT---
>tr|M2ZVR2|M2ZVR2_STRMB Beta-ketoacyl synthase (Fragment) OS=Streptomyces mobaraensis NBRC 13819 = DSM 40847 GN=H340_29676 PE=4 SV=1
DALFRLDWTRVEVRGDG-GRPRSALVALPGEPLAAELAEVLDAPAVCVTP----EEEPYDAGEFARQSSVSGSSRVVVAARPGETAGDLPGASLWGLVRS
AQTENSDEPELALRDG---LMYVPRLVRDDRLGSATWRLAAGVGAVSVGDRVVAPVPSGWSWTRAAGSLHRLVDARLLDVAAAGGTA---PADSPDAVLA
VRDGAEGPVWDVRREALGSGYAASRPPVL-TLPVAFDPNGTVLITGGTGALGSLVARHLVTRHARNLLLSSRRGAEAPG--ALELAAEL----AALGAHI
TFSACDPGDRKAAEALLASVPAE--HPLTAVFHCAGTVSDAVVQNLSAEQVEEVLRVKADAAWNLHELTADADLSAFVLYSSVAGLLGGAGQAGYTAANA
FLDALAAHRQ-AGGAAATSLAWGYWRLTEGMSGLSDADRARHAGVVGLGADEGLALLDAAWDSGLPLLAVRLDLARMRRQA-----------------RS
HSAA----PTLLRN---LVRGGA--------------DRAAAGPSGPSALLRTLSG----LPAAEREQALLDLVCSHVAAVLGYDPVNATQGLRELGFDS
LTAVELRNRLSAATGLKLPATFVFDHPDPAALARRLGEELAPQ-------
>tr|E3FL65|E3FL65_STIAD Polyketide synthase AufI OS=Stigmatella aurantiaca (strain DW4/3-1) GN=aufI PE=4 SV=1
EWLYTLEWKRHEGASLE-HGPE-WLVLSDTTGTGQSLAELMQRGQRCVLVTAADRYAQLGPGRFQVNAAAPEDYRRVLKDAFGEAGGCRGLIHLWSLDTG
GL----EDLEPAQRLGSQSALYLAQAVREGRDTPRLWLVTQGAQAVSQGERVSVAQAPLWGFGRALSLEHPELQTTLVDVVADAPRA---QAQALWAEMG
AADGETQIAWRQGTRSVARLVRGTYGDTG-AVLPSLHANATYLITGGLGGLGLTLAKWMVTRGARHLVLVGR-GEPSPT--ARTVLREL----EEAGATV
VVERADVANRAQMAGVLGRHHEQ--HPLKGLVHAAAVLDDGTMLELDAERFHRPMNAKGHGAWNLHTLTAGWELDFFVMYSSAASLLGFPGQSNYAAANA
FMDALAWHRR-GQGLPGLSINWGAFAEVGMAAASNRGERLRH-GVGSLKPEQGTAVLERLLAGSSAQVAMQLEARQWLEF------------------Y-
PNAS----APLWTV---LLAEQA---------------KTKSRESTSVRFREALSK----AEPSQRGALVEEHLAEQIALVLRLEKIDRLRALGELGLDS
LMSLELRNRLEAALGMKLSATLLFTYPNLASLAQHVVGRMEFP-------
>tr|E3FL63|E3FL63_STIAD Polyketide synthase AufC OS=Stigmatella aurantiaca (strain DW4/3-1) GN=STAUR_3983 PE=4 SV=1
EWLYTQDWKRYEGAPLD-HGPEDWLVFADASGTGDALAGLMESGQRCVKVAASDHYEKLKPGLFRINASAPEDYRRVLQDAFGEAGDCRGIIHLWSLDST
SN----EHPEHALQLGSQSALYLAQAPRQGRDTPKLWLVTRGAHAVSQDDSLSVSQAPLWGFGRALSLEHPELQTTLVDVLSSDAPS---QAQSLWAELG
ASDGETQVAWRSDTRHLARLVRGSYDSLG-GEPISFHPEASYLLTGGLGGLGLSVAKWMVSKGAKHLVLLGR-SEPSAA--ARLVLDSL----EQSGASV
LVERADVSDLDQLSSVLQRHSSP--FPLKGVLHAAVVLEDRTVLELDSERFLKPMGPKVQGSWNLHSLTSQLPLDFFVMYSSAASLLGSPGQSNYAAANA
FMDALAWHRR-RQGLPGLSINWGAFADVGQAAASNRGERLSL-GISSLKPAQGTAVLERLLTGRATQAAMQLDARQWLEF------------------Y-
PSAS----SPLWGQ---LLAERA---------------KAKAEDPGAAQLREALRK----AEPGRRLALLEEQLAKQMARVLRLDKLDRMESFTNMGLDS
LMSLELRNRLEATLGLKLSATLLFTYPNLAALADHLLGKLSSV-------
>tr|E3FL62|E3FL62_STIAD Polyketide synthase AufC OS=Stigmatella aurantiaca (strain DW4/3-1) GN=aufC PE=4 SV=1
EWLYTLDWKRYEGAPLD-HGPQGWLVLLDGGKTGTALAGLMESGQRCVKVAASDHYEKLEPGLFRINASAPEDYRRVLQDAFGEAGGCRGIIHLWSLDST
SN----EHPEHALQLGSQSALYLAQAVRQGTHTPKLWLVTRGAHAVSQDDSLSVSQAPLWGFGRALSLEHPELQTTLVDVLSSDAPS---QAQSLWAELG
ASDGETQVAWRSDSRHLARLVRGSYDSLG-GEPVSFHPEASYLLTGGLGGLGLSVAKWMVSKGAKHLVLLGR-SEPSAA--ARLVLDSL----EQSGASV
LVERADVSDLDQLSSVLQRHSSP--FPLKGVLHAAVVLEDRTVLELDSERFLKPMGPKVQGSWNLHSLTSQLPLDFFVMYSSGASLLGSPGQTNYAAANA
FMDALAWHRR-RQGLPGLSINWGAFSDVGQAAASNRGERLLH-GVGSIKPAQGTAVLERLLTGRAAQAAMHFEARRWLES------------------Y-
PGAS----SPFWAE---LLAEPT---------------PAGAEEPGTLHIRQALID----AEPTQRRGLLEEFLTKQVARVLRLDKLDRHEAFTNMGLDS
LMSLELRNRLEATLGLKMSATLLFTYPAIASMTEYLLSQPTLT-------
>tr|U9VNL7|U9VNL7_9CYAN Polyketide synthase family protein OS=Leptolyngbya sp. Heron Island J GN=N836_21160 PE=4 SV=1
-HLYEVVWEPAAARAQTLDHPGHWLIFAHSHGIGDTLAQLRQRGHGCTLVLPGTCYQQTQDDHYQLDPAAPEQFQQLLADLLTK-QPWHGVVHLWSLARD
QQPTDGVEPARSQLLNTGSALHLVQALTHTQISPQLWLVTQGAQPIDT-APLQVQQSPLWGLGQAIALEYPELQCMRLDLDPTEAAA--LSAERLLNELL
SAAPDNQIGYRQGNRYGARLKPVTLPSTPMPAIEAVQATGSYLVTGGLGGLGLKAAQWLIDQGAQQIVLASRRGLSSSA--LADKIEL----LEQQGANI
TVVQADVAQQDDVGRLLASCP----APLRGIVHSAGVLADGVLQQQSWQQFETVMAPKVSGAWNLHCLTQEMPLDFFICFSSAAAITGTLGQGNYIAANA
FLDTLAHHRQ-RLGLPALAVNWGAWADVGMAANLSQQQRLAAQGIDLIPVTDGFALLSQLTLQTKPQIAPMTDWSKWLDSLQT-----------V-----
--------PQFYEALV----SRQTAASQSSFIS-------------A----------AANPPVFTQKEQLIAHVQQLVARTLGFTQISLRERLFDWGLDS
LMAIELRGHLQQSLACTLGSTLLFDYPTIEKLVDYLAADV----------
>tr|A0A061A4A2|A0A061A4A2_9ACTN Beta-ketoacyl synthase OS=Streptomyces iranensis GN=SIRAN9186 PE=4 SV=1
GWQYRVTWRRTEG-S-ERPLTGRWLVVVPADWLEQAIAALTARGAQVSRVTVP--------------VD--ADVEALCHELVLDGQRAGSVVSLLPLDTA
GDT-----DAVSVSVGLRGTLALVRAVSTLGLSTPIWCVTQDAVAVRPGDVTQPRQAALWGFARHAGLEQPVPWGGVVDLPREVGQA---DLAALAGAL-
-GDGESELAVRGGTVFCRRLTRVTAPAH----RTPQPLERSALVTGGTGALGAEVARWLVARGARHLVLASRRGPAAPGA------AELAAELAEQGVSV
SVVACDVAERAQLAELLDTWPA--EHPLTTVVHTAGVLDDGIIDRLTPERFERVFRPKVAAAWHLHELTRDHDLVDFVLFSSFVGTVGPAGQANYAAANS
SLDALAAHRR-ALGLTGTSIAWGLWQGPGLADRDGVERQLAARGLRAMDPRGAIQAMDQVIDRDETAVVADVEWSSFATELVGT----------------
--R----SVSLLAELLPA---------SGA---EPG---GPAEGADATGVRERLAGL----PATERAYTITELVRTTVAAVLGHSSVESGRSFQEIGFDS
LTALRLRNRLGAATGLQLPATLVFDYPTPASVAELVGSELF---------
>tr|J2JPY8|J2JPY8_9ACTN Beta-ketoacyl synthase (Fragment) OS=Streptomyces auratus AGR0001 GN=SU9_33853 PE=4 SV=1
SWRYTVRWTPLSERT-AAALHGTWLLVAPAAQVAAVQDALTAHGARVRLVDLA--------------PE--DGSERTTGRLRA-DDDITGVLSLLPLDER
AHP-----DHPAVPLGLSGTLALLQALGDLGIEAPLWCGTRGAVAIGRSEVTHAHQALVWGMGRVAALEHSDRWGGLLDLPETLDKR---AADRLCALLA
GPDGEDQIALRGSGAYGRRLVRAPLAGTP--AQRTWRPRGTVLVTGGTGAVGGHIARWLAREGAEHLLLTSRRGADAPGA------AELEAELTALGSRV
TFAACDVADRDALADLLATVPE--QHPLDAVMHVAGSLDDGVLDSLDPGRMDTVLRAKVTAALNLHELTRDRDLSAFVLFSSTSGTISGPGLGNYAPGNA
FLDALADRRR-ADGLPATAVAWGHWSGDGMGEGA-VGERLRRYGVYDMQPELACGALRQALDHDEAYSVTDLGWDKFTPAFTAS----------------
--R----PSALLRDLPDA---------QRVLEAQES---DDT-GSDAAKLLQHLAGL----SESERAAMVLDVVRSYVATVLGYSAVDPERAFSDLGFDS
LSAVELRNGMNGITGLRLPATLVFDYPTCAVLADFLLAELS---------
>tr|D5UX39|D5UX39_TSUPD Acyl transferase OS=Tsukamurella paurometabola (strain ATCC 8368 / DSM 20162 / JCM 10117 / NBRC 16120 / NCTC 13040) GN=Tpau_347
AWTEAAHGRLAPVDP-ARE----CP------S-----------------------------------------------APTEPGISMRARYAEMAENGT
VAL-----PEGVGVRGFSIHPALLDAALHTISATQIYDTVFEPPQELPDAGSEPEPRTFADIADGADPAASAAAGLWRSAI-NEYPG---QFGIIRTALT
LTSAEPNLAISDGTVRVPRLRPVSDTETA---SPARLDHGTVVITGASGTLGEALARHLREHRTPSLLLVSRRGADAPGA------AALAEELAGLGTRA
EFIAADVADADSVRAMLAHVPT--HAPLSAVVHAAGVLSDGVLSAMTPRRLAEVYRAKVDAVLTLHRATRHLDLDAFVVYSSIAGVVGSAGQGNYASANA
FLDAFARGPH-S-GGRTVSVAWGLWAEASMTSVLTDRERVSRAGLTGMSTADALALLDAALPARDGAIRSAFDTAQLGELARSG----------------
--D----IQPVFRALAPG---------RRR------------EPVAPPSLAQRLTRV----AEEDRLELATDAVAEVAATVLGYAELDTRRGLLELGFDS
LTAIELRNRLGAATGLRLPATLIFDYPSAAAIAAYLIEQAV---------
>tr|A0A0N1K5V1|A0A0N1K5V1_9ACTN Polyketide synthase OS=Streptomyces sp. NRRL S-4 GN=ADK82_24130 PE=4 SV=1
SWRYRISWKPVAPAT-APAPSGTWLVVSPSGGEA-VTRELVRNGARTVQVLFE---------------S--DDTAMALQRLGADGGRIEGVLSFLAEDDR
PDP-----FHPVVPAGVAATTSLIQAMTDLDLAAPLWCLTRGAVSVDGPGLTGPAQAQVWGLGRVIGLEHPDRWGGLIDLPAEPDER---TAAQVCRLLT
GAGDEDQLAVRPQGVFARRLGRSPAGPRPA-APTRWEPRGTALITGGMGALGSHVARWLASNGAEHLVLTGRRGEDTPGA------LALKDELMALGARV
TLTACDVADPDALTALVKELAQDDTAPVRAVVHAAGESLVSGLEESDPAEFARVMSAKAAGASSLDALFDSDSLDAFVLFASGAGVWGGSAQGAYAVSNC
HLDAVAERRR-ARGLAATSVAWGGWAGGGMVDAA-AGSTLTRMGLRPMEPEAAVRALVQAVERQETCTVADIDWDRFAPAFAMA----------------
--G----PRPLIEDIPEA---------AAALRPEDD---REAPEAAAGALAARLAGA----SDAERKRMLLDLVRAEAAAVLGHDAVDPKRAFREMGFDS
VMAVELRNRLNTATGLRLETTLVFDEPSPTGLRDRLMRELL---------
>tr|A0A0C1TI20|A0A0C1TI20_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces pluripotens GN=LK07_30850 PE=4 SV=1
PWTQHAAGTVEPQVG-AAPAQGDWP---------------------------------------------------------ETGPEVGELYRLLADRAE
VEL-----PAPAEPGGFGVHPALLDAALHALAGVALYTVDYKPVPAGTDGEPAVTDPGEWLLVNGTDLGAAAVWGLVRSAQS-ENPG---RIVLLPDPVA
LATREPQLTVRDGAVLVPRLVRGTA-GE----PAAWHPEGTVLITGGTGALGSVLARHLAEHGVRHLLLTSRRGPGTPGA------AELVADLAALGATA
KVAACDVADRDALAGLLAGIPAE-H-PLTAVVHAAGVLDDGMLAAQTLERVDRVFRPKVDAALHLHELTRGYDLSAFVLFSSAAGILGSPGQSNYAAANA
VLDGLAARRR-AAGLPAVSLAWGLWAGAGMGETVAAGRRIERLGVVPLDPAEGMRLFDAAVPGRTALVPVRLNLAALREQARTV----------------
--P----PAPVLRGLVRA---------PAR------------RVAGTGALAVAFAGL----DEAARGRLVRDTVRTAVAAALGHAGLGDRRAFTDLGFDS
LTSVELRNRLAAGTGLQLPATLAFDHPSIAATAEYLLGRLT---------
>tr|A0A0F2T6A1|A0A0F2T6A1_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces rubellomurinus GN=VM95_36995 PE=4 SV=1
RWRYRIAWRPVPVPAA-PALSGRWLLLLPPAELAADCRDLAAHGAEPVPVPV--------------DAAT-ADRAALGDALAAADRPVAGVLSLLGLDER
PRAE-----QPLVPAGVAATAAAVLALDDAGIEAGLWSATSGAVRAEKDTVDHPVQAHVWGLGRVAALERPAHWAGLVDLPAALDPRAAARLCAVLGGIE
ADGTEDQLAVRAGGVFARRLVRAPLDGAPAPAARPWRPRGTVLVTGGTGALGARVARALAARGAEHLLLTSRRGPTAPGA--AELAEEL----TGLGARV
TVTACDVADRAALAAVLAAVPSD--APLTAVVHTAGITQASPIDETGPAEHAAVVAGNSAGAAHLDDLLGDRELDAFVLFSSNAGVWGSGGQGAYAGANA
YLDALAEHRR-ARGRTATSVAWGAWDGGGTATDG-ATEQLRRRGVLAMDPEPALAALLQAVARDETFLVADVDWARFVPGF------------------T
AR----RRSPLLAELPEV-RAALGAAEQA--------P-----QPADSDLARRLADT----PPADHERILLDLVLTEVAAALGHDALEAGRPFKDLGFDS
LIAVDLRNRLRTAAGLPLPATLVFDHPTPTALARHLREELL---------
>tr|J1RWK2|J1RWK2_9ACTN Modular polyketide synthase (Fragment) OS=Streptomyces auratus AGR0001 GN=SU9_31533 PE=4 SV=1
GWRYRVVWRPLTEPAA-RQLDGEWLVVVPAGYLVHGARELAEAGARTHSLTV-------------------DDRAGLADLLRPGPGPFAGVLSLLALDER
PDRT-----HPCVPTGLSLTLALLQALGDAGIDAPLWCVTRGAVGIGEDAPTNPDQAGIWGLGRVAALEHPERWGGLIDLPGRAGGQTAAQEVALLARIL
AGDDEDQLAVRGSALFGRRLLPAPVAG--KPPRRSWRPRGTVLVTGGTGALGAHIARWLAADGAEHLVLTGRRGADVPGV--AALCSEL----RDQGVRV
TVAGCDLADRQAVAELVRQIERDG-EPVRAVVHAAGVSALGSLAEAGPADLAAALAGKVAGADHLSSALDPAQLDAVVYFSSISGTWGVADHGAYAAANA
LLDARAERGR-ADGLPVLSVAWGPWAGGGMIADS-IHDVLRRRGVPVIDPDTALTALQQALDHDDTSIVADVDWRRFHSVF------------------T
SV----RPSRLLTEIPQL-AADEDGDGPG--------DDGSDRGSARSPLAEKLAGL----DVRQRTAALLDLVREQVASVLGHAPVDPERPFKELGFDS
LTAVELRNRLSRATGLRLPRTVVFDHPSPAALAGYVGTQLT---------
>tr|A0A0N1K6E0|A0A0N1K6E0_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. NRRL S-4 GN=ADK82_26560 PE=4 SV=1
AWTRHADWPPAGAR-A-VAVDTLYATLADAGYLFQGLRAWRQDGFGLHPALL--------------DAALHVRREGSGASLADGAGS--HVASVESLALR
PVSE-----WSVKPVGVAQSA---------DRAEGSWAVVGEAEFLPVCDSPDPVQAAVWGLLRTAESENPGRFVLVD-HD---------QEP-LLPA--
VASGEPQAAVRAGEVLVPRLARVPLPV--GQIPAFVEPSGTVLVTGASGVLGGVVARHLVEHGVRHLLLLSRRGADAPGA--ADLVAEL----AESGAQA
RFAACDVADRGALAEVLDSVGSE--HPLTGVVHTAGVLDDGVVSSLTPERLAAVLRPKVDAAWHLHELTRDMDLSMFTLFSSAAGVFGGAGQANYAAANA
FLDALAEVRR-AEGLAGQSLAWGLWAQAS-TGQL-DSGDLRRMARGGLTPLSSVQGLDLAGLADEAVLPIRVDMARLRPEM------------------T
PL----MLR-GLVRVPNR-RQAD---------------SG-TD--RSASFGRTLLAL----PEAEQRQLVQDLVRAQAVAVLGHEAVQPERAFTELGFDS
LTAVELRNRMSAATGLRLPATLVFDYPTPFAMADYIRTEIV---------
>tr|A0A0C2BI28|A0A0C2BI28_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. 150FB GN=QR77_03315 PE=4 SV=1
SWRYRVEWKALPTGEP-ATLAGHCLVLVPESGLADTVCRIEAAGATVTRTVL--------------TGAD-SDRQTLA--RAEVPRPVGRVVSLLGLDES
PHPD-----HPAVPVGVAVTLSLVQALGDAGIDAPLWCLTSGAVSTGHDPVTGVAQNLVWGLGRVAALEFPRRWGGLCDLADGFDTNALIS------ALA
-THGEDQVALRPDGAFGRRLARAPLPA--APVSETWRPRGTVLITGGTGAVGGQIAAWLAGNGAEHLVLASRQGGAAPGA--AELTAEL----ESLGARV
TTAACDVTDRAQLAALIADIEAKG-DRIRSVMHTAGAGRLVPLPDTDLAEFGDTLHAKVLGAAHLDELIGE--VDAFVLFSSISAVWGSADHGAYAAANA
YLDGLAENRR-ARGLSATSVVWGIWAPQNMAADL-AEQQLLGRGIPFMRPALAIDGFQQVLDHDETVVVAAVDWDRFAPVF------------------T
SA----RPSPLIADLTDA-RQALAGQSAG--------ADG-SEEGSSSPLLDRLRGL----SEAERREVLTDIVRTQAAAVLGHDEIEPGRAFRDLGFDS
LTAVELRGRLNAATGLRLPVTVVFDYSSATALADHVRAELL---------
>tr|A0A0D5EG74|A0A0D5EG74_9BURK Amino acid adenylation domain protein OS=Burkholderia ubonensis MSMB22 GN=BW23_5766 PE=4 SV=1
-PLYHVVWEQQAALPAAAADASPWLIFADESGAGDRFAALLARGASCALVRAGRDYRAPADAAWQVAPEQPDHFVRLLKEAAA---PGQRIVFLWALDET
VGA----------SRMSTALLHLVRALGSGEARPRIWVVTRDAVEAGEARVSGLAQAALAGLARGAMIEHPEWFGTAIDLDPAAPE---DETQALLHEVL
GESREEQVALRQGARYVARLSPLAQAET---AALRVDPEAAYLVTGGFGALGLHTARWLAAHGARTLILVGRQGAA--SDESQRAIAELR----ERNVTV
RCERLDITDPAAVADCFAALRRER-VPLRGIVHAAGIVGHKPIMQVEREELEAVLQPKVAGAWLLHQHSEPFPLDFFILFSSIASAWGSRDQAHYSAANR
FLDALAHHRR-HLGLPASSVNWGPWAQGGMTFPE-AEALLRRVGIRSLAAARALDVLDHLPAV--PQVVVDVDLALFQRS------------------YE
ARGPKPFLDRV---------------------RVDATPPS------APAMPALS-----DKSPRERKRLLADAIDRAVAQVLGFATPDRDRGFFEMGMDS
LMAVDLRAHLEKALGAPLSVALLFDHPTVNALADFLAEQSS---------
>tr|A0A0F5A3P8|A0A0F5A3P8_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. MUSC164 GN=VT50_35900 PE=4 SV=1
SWRYQTTWKRLPTPSTRPDLSGTWLLIIPSGGVTTATQALTAHGATSLRVDTRA-----------V------DRDTLADQLTATEGAPAGVLSLLALDEE
PHPQ-----YAAVPSGLTATTVLLQALGDAEIAAPLWCLTQGAVATPGSPLPGPRQAQTWGLGRAAALEHPRRWGGLIDLPIVIDH---HTADRLAALLA
PGGPEDQSAIRATGSYARRLRRAGTPTT---APRTWQPTGTTLITGGTGGLGAHIARWLARRGAPHLHLISRSGPDAPGA------AQLSEELNVLGTTV
TVTACDVSNRAALQHLLDTIPA--EHPLTTVVHAAGTSDTELIAELGPERLQGVLGPKALAAAHLHELTQGLDLSAFVLFSSGAASWGGSRQGAYAAANT
YLDALAEHRR-ARGLPATSIAWGPWGDAGMAADDTALAFYGRRGLSPLGPELAVASLQHALDHRDTTTVADIDWEKFPTAFTA-----------------
-QRP----SPLLDDLITAA------ENPT-----ERITEASATTSATTSLQQRLSA----TTPEQQHQLLRERIQSLAASILGHDAIPPAQPFQELGFDS
LTAVELRDQLATATGIDLAPSLVFDHPTPNALAAYLLAELM---------
>tr|M3D294|M3D294_9ACTN Type I polyketide synthase (Fragment) OS=Streptomyces gancidicus BKS 13-15 GN=H114_03364 PE=4 SV=1
RWRYRVVWRTHDLPATR-TLDGTWLLAVPETLVAAVARTLSQAGATTVTADAGD-----------L------DRERVAARLAAEPASVQGVVSLLALDER
PAPG-----HPGATAGMTSSLVLLQGLLDADLDARLWILTSEAVTTTGDVVRNPLQGALWGFGRVVALEQPRRWGGLVDLPAELDE---DTARGLVAVLA
ARSDEDQTALRGRTAHIRRLVRAPAGRP---APRAWRTSGAALVTGGTGGLGAHTARLLARKGAEHLVLTSRRGPDAPGA------EALREELTALGCRV
TIAACDVADRDALERLVAEVEA--DGPARTVVHTAGVGMLAPLAETDLDFFAEGARAKLLGAANLDAVFDHDRLDAFVLYSSVAGTWGSGDHGAYSASNA
YVDALADQRR-ARGLTGTSIAWGIWSPEGGGMAVVVREQLRWRGIPFMDSDLAVTGLEQALDHDDVFAVADIDWERFVPVFTA-----------------
-AHP----RPLLHEVPEVA------EAMK-----ADAPDEDTSADRLGGLRAELAA----LPAAERVRTLTDLVRTQVATALGHEEIAPQRAFRELGFDS
LTAVELRNRLNAATGLSLPATVVFDFPNVNELVRHLLEHLV---------
>tr|E3JCX3|E3JCX3_FRASU 6-deoxyerythronolide-B synthase OS=Frankia sp. (strain EuI1c) GN=FraEuI1c_3089 PE=4 SV=1
NWRYRVAWRPVTPSPG--RVPGHWLLAAPADRDAPATQALVERGARVTTVRVGADVER---------AAVAAAIRSALAAADSPTERVAGVLSVLGLRSD
LLPD----H-PSVPWGLGATVGLIQALHDLGLDTPVWLTTSGAVTTPGDAVREPEQAMVWGLGPVLAAENPAGFGGLIDLPAEVDE---RAAARVADLLG
GHHGETELAIRAGAVHARRLVRAPATETD---TATYTPTGTTLVTGATGAIGQHLARWLAHNGAPHLLLLSQRGPDHPD--AARLTHDL----AQNGTHV
TLLAGDIADPHHLTHALTHIPPN--APLTAIYHTAAILDDALTTDLTLTQINNTTRVKVDGARNLHHHT--HSLTHFVLFSSMAGISGITGQGNYAPGNA
YLDALAHHRR-HHHQPATSIGWTHWAKAGDGTGDAVETRLARRGLTLLPPAAALTALHHPLTHDTTHLIADLDWNAFGRDQ-------------------
-------PGQLTAELRTAPAPR---SGTAST--EAARPGSA--RDAAGRLSEELATL----PPARRAARLRTLVRAEASAVLGHDRLEPTTSFRDLGFDS
LTAVELCNRLRTASGLALPSTLIFDYPSPDSLAEYLAKRLALDAA-----
>tr|E3JCX2|E3JCX2_FRASU 6-deoxyerythronolide-B synthase OS=Frankia sp. (strain EuI1c) GN=FraEuI1c_3088 PE=4 SV=1
RWRYRIAWQRVAAEPA--PLTGDWLVTVPDELDAPWVRVLTGREASPVLVRVARDATD---------RALAGLV-------KGLTGPPRGVLSLLGLAEG
SHPD----F-PSVPWGLAGTVGLIQALHDGDIPAPIWAVTRGAVTTANDPVTDPEAAMVWGLGSSAAAENPAGWGGLIDLPGTIDQ---DSLQLLATAL-
GQTDECDLAVRPGGLSVRRLVRAPMTEPD---ATPFTPTGTSLVTGATGAIGQHLARWLAHHGAPHLLLLSQRGPDHPD--ADQLLKDL----TATGTQA
TLIAGDIADADHLTHALTHIPPN--APLTAIYHTAAILDDALTTDLTLTQINNTTRVKVDGARNLHHHTDTHNLTHFVLFSSMAGISGITGQGNYAPGNA
YLDALAHHRR-HHHQPATSIGWGHWAGG-------IEAQLARRGLTLLPPATALTALHHPLTHDTTHLIGDLDWDVLWRDK-------------------
-------PDRLYRDLLRQPPAG-----PAAI--EPAAPTAA----PRQGLAGRLADL----PEAEGRRTVLRLVRAHVAAIGGFDAVDVRVPFRDLGFDS
VTAVELRNRLGNETGLRLATTLVFDHPSPAALAEHLFAELAPAAG-----
>tr|E4NJF5|E4NJF5_KITSK Modular polyketide synthase BFAS5 OS=Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / 
GVALRAAWRTPDARPE--GLPFSWQRVALH-DDAPVLRP---DGPDAVTARITDPAGR---------TATVGVFHVGWTPVAAPGPRPVTRWGLLGPRDE
RLP---------DPGAVHAVLDRVQAADDTTARTPLVVLTRDATGPARPRPADPGAAAVWGLLRAAQLEHPDRFVLL-DTDGPDQDGLPGLGDALADLL-
-AGGEPQAALRGGVLYAPRLVRPPAPATA---PGAFGPAGGTVLVSGGGALAAVLARHLAAHGVRRLLVLSRRGADAPG--LPELAAEL----AAAGAEL
TALGCDVSDRRALAAALATVPEE--HPLCAVVHTAGVLDDGLLDGLTAQRAAAVLRPKFDAAHHLDELTRGADLAAFVVFSSAAGVLGSPGQASYAAANA
ALDALVAERR-RLGLPGLSLAWGPWARVSGMTAEADRRRIDRRGARGLSDEEAMALLDTVCAADGSPVLAHLDL---GDGP-------------------
-------VHPMLRALVRRAPAG---AAA---------PTAA----A--ALRHRLDAA----ADGERERVLRELVLAEAAGVLGHGALSATEPFLSVGFDS
LTAVELRNRLAALTGVRLRPSAVFDSGTPAALAARLAAEARTEDA-----
>tr|A0A0L0L427|A0A0L0L427_9ACTN Polyketide synthase OS=Streptomyces stelliscabiei GN=IQ64_12045 PE=4 SV=1
GVHLRAAWRVGDALPA--SVPFSWHDVTVA-PADPVLRP-APQGGDAVSVRITDRTGR---------PVTVGLFRLDWTRLPTGP--ATGTWAVLGTSGG
GLPD----L-AD-PEAARAALDLLQRAEPKFTETPLVLLTRGAVD-LDGAPADLGGAAARGLLRTAQLEHPGRFVLL-DTDGG---D--GLEAALATAL-
-AEGEPQLALREGILYAPRLVRAPVADR-----AGFGPEGTVLVTGGGGTLGGLVARHLTTHGVRHLLLLGRRGAAAEG--MAALTEEL----SAAGAEV
TVAACDVADREALAARLAAIPPE--HPLRAVVHTAGVLDDGLLTALTPERLSAVLRPKADGAWNLHELTRDQDLTAFVLFSSSAGVFGSPGQSAYAAANA
FTDALAAVRH-RAGLPGTSLAWGLWEQRTALTDGGDLRRMARSGVRALPTEEGLALFDAALAGDDPVLPVGLDL---PGGP-------------------
-------VPHLLRSLVRTPAAR---RRG---------PEPE----A--SLRPRLAAV----PE-EQGEILLRLVRTQAAEVLGHDALSEGDAFLESGFDS
LTAVELRNRLAAALDLRLRPTAVLDAGTPARLAGHLRAELTRSTA-----
>tr|D7AWH7|D7AWH7_NOCDD Acyl transferase OS=Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488) GN=Ndas_0496 P
GYGLRAAWREGGRLPD--GHPFSWTGVRLY-AGADHLRP---VGPDEYALTMTDTDGN---------PLTAELYALEWPTVDADTGPL-PALAVLAPDTT
GLEE----L-REVPEDAGASLELLQEADEGATDHRLIVVTRGAVAVPEEDVTDLVHAPLWGLLRSAQAEQPDRFTVV-DLDGSD-----AAAATLTRAL-
-ASGEPQLALRGSTAHAPRFTRARVPGES---A---LGGGTVLVTGATGVLGSAVARRLERHGARDLLLLSRRGGGAPG--ATALVEEL----TSLGARA
AFAACDVSDADALAAVIDAVPEE--RPLRAVVHVAGGIDDGVLATLTPESLDAVMRPKADAAHHLHRLTEHLDLAAFVLFSSAAGVLGSPGQANYAAANT
FLDALAHHRR-SRGMAAQSLSWGLWERLGEAGSHEDISRLRRLGMRTLEQREALDLLNAALACGAPHLPLPLDLEGVRTGQ-------------------
-------VPPLMRGLVRQPRYR---ASK---------GGAA----EGAGVSAAL-AA----STEERERLLLELVGALTTEVLGRESPDPDQDFLELGMDS
LTAVELRNELRAATGLRLTASVVLAHSTPARLARHLAAELPEPGS-----
>tr|A0A087NRY0|A0A087NRY0_BURPY Amino acid adenylation protein OS=Burkholderia pyrrocinia GN=JM78_19285 PE=4 SV=1
--LYHVVWEPQAALPAAAADASPWLIFADESGVGERLAALLERGASCSLVRPGLDFGVGAEAGRQIAPERPDDFVRLLNETAA---PGQRIVFLWALDEV
VGE----------TRMSTALLHLVHALVGSETRPRIRVVTRDAVEAGEAPVSGFAQAALSGLARGAMIEHPEWFETAIDLDPAAPE---DETQALLQEML
GESREEQVALRHGARHVARLSPLAQAET---AALRVDPDAAYLITGGFGALGLHTARWLAARGAGTLILVGRQGAA--SDESQRAIAELRE----RNVSL
RCERVDIADPVAVTDFFAALRR-DGVPLRGIVHAAGIVGYKPIMQVGREELDAVLQPKVAGAWLLHQQSEHFPLDFFILFSSIASAWGSREQAHYSAANR
FLDALAHHRR-SRGLPALSVNWGPWAQGGMTFPD-AEALLRRVGIRSLAADRALDVLDHLPAV--PQVVVDIDLALFQGS------------------YE
ARGPKPFLDR----V------RVGGS-PPR----------------APAMPALS-----DASPRERKRLLADSIDRAVAQVLGYGTLDRDLGFFEMGMDS
LMALDVRTHLEKALGIPLSVALLFDHPTVNALADFLAEQSS---------
>tr|D0LS52|D0LS52_HALO1 Acyl transferase OS=Haliangium ochraceum (strain DSM 14365 / JCM 11303 / SMP-2) GN=Hoch_1182 PE=4 SV=1
DWLYELAWQRIDAEAEADDASARWLILADRGGVGEALAERVG-RSRCVLMYAGEAFQRSSERTITVAPAALDEFHAAIAVLVEGGQAIGRIVHLWGLDIP
SWDLDLEALERAQDLALTSVAFLVQSVAER-VSAPLWLVTRGSQSPEGAADLSVVQAAIWGMGRVIAQEHPALWGGLVDLAPTGAGGAAAEAAALAEHLA
HATPGEEVALRGEQRYQTRLVRAVASDE--TKPVSWRNDAAYVVTGGLGGIGAEVAAWMAERGARRLLLLSRSGVPPRSEWETAERARLVRRLEQLGACV
EVAALDVADEAAMRGYFERYQREGRPPIRGVVHAAATVSGRSMLTIDRASIAADLAAKVRGGWLIDRIFG-EQLDFAVFFSSASVFFSSPFLGSYAAANA
FLDALAHQRR-GRGRAGLSINWGFWEDVGLAARRALGAELAPKGMGSFTPEQGIEAMHRLLGRPRAVAVMPINWRTWSAHHEAAA---------------
-------TAPLLAHLAA----TSSENHA-------------EHAADEPGAIRLLDTLAEITETWRRLERLESFVRTQLGAVLRRDDIGRHTPLGSLGIDS
LMALELRRGLERETGLTLPATLIWTYPTVAELAGFLSEQLVAPAA-----
>tr|A8M2E8|A8M2E8_SALAI Amino acid adenylation domain OS=Salinispora arenicola (strain CNS-205) GN=Sare_2407 PE=4 SV=1
GWLAEPAWVPLPPLAEPTPAGARWLILADGTGLAEEFAGLVAHGGQCHLVRPGTALHVVSAGRSTVRPDSAEDLRHVLAG----SGGPGHILHLWNLDLP
DFGETAMDLPHCGTLGAYSLIALAQALSGQKTGGRLHVVTRGSQAVDGSGVTQPTGAPAWGVARVLRQELPGHCGKIVDLGVPSHT---AEAAELWREFA
-HDDEDEIALRGGDRFTCRLRPAVELHR--PLPLRLRPDGAYLVTGAFGALGRLLCRTLVRRGARRLVLVGRTPMPPRERWDRERIAFLTE-LETLGCQP
LVAQVDVTDEHALTLWLGEYRRRRSAPIRGVFHLAGQVRDTRVERMDRETFDAAYDPKVAGAYLLHWHLRDEPLDHFVLFASIASLLTTAGQANYAAGNA
FLDALAHHRR-ASGRTALSLDWGPWA-TGMIEELGLVHYRNNRGMSSLSPNTGMAVLERVAGESRPQLIVVVNWPTFLS------------------WYE
-R-----PPALVTELAA----TT--ASP----------A------DAA-HSSFLEEFRD-AGEDDRHRLLSERFVAVVADVLPVETVDRSAGVTALGLDS
LLAMELRARISAELHVALPVVALLSGVSVTDLIGQVHEG-----------
>tr|W7J718|W7J718_9PSEU Uncharacterized protein OS=Actinokineospora spheciospongiae GN=UO65_2903 PE=4 SV=1
GWLSRVSWRPVPDPAPIEGPLGRWLLFADRGGVAEELAARVAEGGHCHLVRTGPAYRAG-RWESTVVPGDPTHLSRLAADLADGETGFEAVVHLWNLDLP
GADADRAALD--PAAGAYSLITTAQSVLAGELTGRLHVVTRGTQAVRAEDPVEPIGARAWGISRVLWQELTAHRGVLVDLEPGAPDRA-AEADALLRELA
ADPDVDEVALRGGVRHTSRLVPAADALT-APLPPRLRQDGAYLVTGAFGALGRLLCRTLVSRGARRLVLLGRTPLPERAWWDARFVRD----LEEAGAQV
ILAPIDVTDEAALTRWLAGYRRDHGLPLRGVFHLAGHVRDTLVPDMDRATFDAVHDPKVVGAWLLHRHLRDEPLDHFVLFASVASLLTTAGQTNYAAGNA
FLDALAHHRR-SRGLPALSLDWGPWA-TGMIEELGLEHYRVSRGMSSLSPEAGMAVLERVLGQEQAQLLVVVDWPTFLS-------------------WY
ADP-----PPLVAELAAA-----------------ATEVTETGG----SFLDVF---R-VADDATRRELVAERFTALVAGVLRPEKVDQGAGLTSAGLDS
LLAMELRAKVNTELKVSLPVVALLSGAPVAELVEQVHAG-----------
>tr|A0A0M9YGN7|A0A0M9YGN7_9ACTN Polyketide synthase OS=Streptomyces sp. MMG1522 GN=ADK56_30120 PE=4 SV=1
SWLAEPVWTDCPPLPAATAPAHDWLLLADAGGTADAFAALAARGERCRLVRTGAAYTAS-GDGYTVDPASDADLRRLFADLDRDGPFHGTVLHLWNLDAP
ALADDRPALR--DGAGAYSLIALARLLAARGAEGRLHIVTRGAQPALPGEGPEPLGAPAWGIGRVLRQELTGHPGKLIDLDPGRRPGP-DEDRAEAALLA
ESDDEAEIALRDGVRRTSRLRPA-ENLT-RPLPPRLRPDGTYLVTGAFGALGRLLCRTLVRRGARRIVLIGRTPVPAREKWAGALLRE----LEALGAQP
VPATFDITDEDALAVWLDAHRRSGAPPVRGVFHLAGQVRDTLVADLDRAAFDSVHDPKTVGALLLHRHLRDEPLDHFVLFASIASLLTTAGQTNYAAGNA
FLDALAHHRR-ARGLPALSLDWGPWA-TGMIEELGLDHYLHSRGMSSLSPEAGMAVLERVIGQDHAQLVVVVDWPVFLA-------------------WY
PSP-----PPLVAELAAA-----------------AAPDAASGN----GFLDTF---R-AAGEEARRTLVAERFAALLAAVLRADRIDPATGLGDLGLDS
LLAMELRARVHAELGVALPVVALLSGTPAGELAAQLHDG-----------
>tr|A0A060ZF29|A0A060ZF29_9ACTN Modular polyketide synthase OS=Streptomyces iranensis GN=SIRAN1399 PE=4 SV=1
SWRYHVTWKPLGDALTSSSAGATWLIAAPAGEEGPRVAELRERGAQVRELTEADAV-----------------REALARRLGEATTPPTAVLSLLALVED
LY-----RAGTAQPLGLALNLALLQALGDTGADVPVWYATRGAVSVGRDALDHPLQALSWGLGRIAAVEYPRRRGGLVDLPGTLDD---RAVARLCGVLG
RLTDEDQVAVRASGVHGRRLVRASAAAD---AIAPWRPRGTVLVTGGTGGLGAHVARWLARGGAEHLVLTSRRGPDAPGA--AELADE----IRESGVRV
TVAACDAADREALAGLLATLDAD-EAPLDAVVHTAGVLDDGVLDALTPERADGVLRPKVDAALHLHELTRDRELSAFVLFSSFAGTLGGPGQGSYAAANA
FLDALAHARR-AQGLPATSVAWGAWSGGGLVDEA-VEARLRANGMPVMAPDLAITALQRALDVADTHVVADVEWDRLIAATPSLD---------------
-------GAAVLGELPDA--------RRAE----AAAA--TAGERDT-PLAQRLAGL----SPQEAEEALADLVSTEVAAALGYAAVEAGRAFRELGFDS
LTAVDLRNRLNAATGLRLPVTLVFDYPTVTALVRFLLAES----------
>tr|A0A0N1K131|A0A0N1K131_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. NRRL F-6602 GN=ADL27_53860 PE=4 SV=1
SWRYDIQWQPLPQAAAPRIDGARWLLLVPAGGVSEHVSQLTALGAEVREVEHAERA-------------------ELAARLREIG-GCTGVLSLLALGDD
PTDPGDFDQSDFDQAEFDRAVLVVQALGDAGSTAPLWFATRGAVRVGSDRSADPRQALLWGLGRIAALEYPQRIGGLVDLPAEPDE---RAAERLARALG
APDGEDQLAVRAGGVYVRRLARKPLGLT---PVRNWRPTGTVLVTGGTGGIGAEIAAWLASNGARHLLLAGRRGDRAPGA--AELAER----LTGLGARV
TIAACDVADREALRGLLAGIDP--EHPLTAVVHAAAVLDDCLLDVLTPERARSVLLPKVAAARHLHELTEGADLDAFVLFSSIAGTLGGPGQGSYAAANA
YLDALALARR-AAGLPATSLAWGAWDRVGLATGE-TGEWLSRNGIVAMEPEAALSAMRQAVDHDLPHLVADIDWAVFGPACTPGR---------------
-------SGRVLEGLPEA--------RPAV----GRAP--DEEQVVG-GFAADLAGR----SPAERQQALLTLVRGQAAAVLGLDAVDLDRALRDLGFDS
LTAVELRNRLNAATGLRLPVTVVFDHNTASRLAGHLSEQL----------
>tr|A0A0J5XC65|A0A0J5XC65_BURCE Amino acid adenylation protein OS=Burkholderia cepacia GN=VL15_08545 PE=4 SV=1
--LYHVVWEQQAALPTAAADASPWLIFADESGVGERLAALLRHGASCALVRPGRDYGGGAEAGWQVAPEQPDHFVRLLNETAA---PGQRIVFLWALDEA
VGAS----------RMSTALLHLVHARAGSSIGPRISVVTRDAVEAGEARVTGLAQAALSGLARGAMIEHPEWFRTAIDLDPAAPA---GETQALLQELL
GEHREEQVALRRDVRHVARLRPLAQADT---AALRVDPDAAYLITGGFGALGLHTARWLAARGAGTLILVGRQGAA--SDESRRAIDELRE----RNVSL
RCERLDIADPVAVADFFAALRR-DGVLLRGIVHAAGIVGYKPIVQVERAELDAVLEPKVAGAWLLHQHSAPFPLDFFILFSSIASAWGSRDQAHYSAANR
FLDALAHHRR-ALGLPALSVNWGPWAQGGMTFPE-AEALLRRVGIRSLAADRALDLLDHLPAVPQA-AVVDIDLALFQA------------------SYD
ARGP----RPFLDRVR------V--------------TGTAAGA---QAMPAL----R-NASPRERKRLLADSIDRAVAQVLGYETLDRNLGFFEMGMDS
LMALDVRTLVETALGIPLPVALLFDHPTVNALADFLADQS----------
>tr|A0A0F2T8G9|A0A0F2T8G9_9ACTN Polyketide synthase OS=Streptomyces rubellomurinus GN=VM95_35935 PE=4 SV=1
SWRYRIAWRRRADPATAPRLTGHWLLVAPTGEPTADVEELTARGAAVTALAVD--------------TASTADRAALADAAAEAGVPVAGVLSLLALAEA
PHPA-----HPAVPAGFPATVALIQAVGDADLGAPLWCATRGGVTVGGDRLGNPFQALYWGLGQVASMEHPKLWGGLVDLPATGCGPA--ELGRLAAVLA
EGGGEDQTAVRADGVHLRRIVRAPLTGRP--PARPWAPTGTVLITGGTGGLGAQTARWLARNGAPRLLLASRRGPDAPGA--AELHAEL----TALGAET
VIARCDVADRAALAALLAGIPA--EQPLTAVVHTAAILDDAVIDRLTPEQVDRVLRVKAHGALHLHELTRGLDLAAFVVFSSFAATFGAPGLANYAPGNA
FLEALAEQRR-ADGLPATAIAWGTWAGGGMAADG-IGERARRHGLHEMDPDLATEALGDALAHDETSVVIDVRWERFAAVFASE----------------
--R----TGRLLDEIPEARKA-VESA--------ERDP--AADAAAPADLRRRLAGA----PEVERDRILLELVRSHVAAVLGHRAVAPARPFRDLGFDS
LTGVELRNRLGSATGLRLPATLVFDHPTPAAMARHLRGELLADT------
>tr|A0A0N9I194|A0A0N9I194_9PSEU Uncharacterized protein OS=Kibdelosporangium phytohabitans GN=AOZ06_39630 PE=4 SV=1
RLRYDVRWQPVTPG--PVGITGTWLVLTPTADVT--WLGLRQHGAEVVQVAAD--------------PTEYE---ELAAETSARPDGFTGVVSMLALDAH
EHGA-----Q--------RASAVLLALREAEIDAPFWAVTRNAVP--GGTVPDPRQAEVWGWGRVAALESPLGWGGLVDLPTDADTGA--ESGGLLAAVL
AGTGEDQVAIRSTGVLACRLVRTPSVA-----NVVTTITGTALVASGDDALGRQIASWLEDAGAERVVLTGATAQDDLA---------------------
--------------ALLKDLGD--GTPVSTVVHAPGPVDLTPLADLAPEQLGAAVSRQLDGVAQLDDLLD-KESVRLVLFSSVAGVWGGSGHGAVAASAA
HVAAVAERRR-ARGLPTTAIAWGPWDRDESS------AQIRRSGVLPLRGDDVFAVLRQALDADTALVAVDVDWPRFADLFTVA----------------
--R----PSPLIDGLLDADQP-D-----------------PQDTPGSGDFVARLSGF----DAETRHHELVELVCKHTAVVLGHTAVDPAKAFRDLGFES
MNAVELRNNLNAATGLRLPATAVFDHPAPVVLARHIHAELFEAP------
>tr|A0A0F4J543|A0A0F4J543_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces katrae GN=VR44_26260 PE=4 SV=1
GRRYGVAWRPVRDE-ARPALRGTWLLAVPEGGAGARVRELLGRGAEVTLLPVG--------------PDAGPE--ELAGALAGAG-RPEGVLSLLGLASG
SHPE-----HPEVPAALAGTLALVRALGQAGVEAPLWVATRSAVATAGDPAPVPEQAQLWGFGAVAGLEHPDRWGGLVDLPEELDGPA---LRRLSGVLA
AGEGEDQVAVRASGVLGRRLVRTA---GG--DGAPWRPRGTVLVTGGTGALGARFARWLAANGAGRLVLTSRRGPDAPGA--AELVAEL----GELGVPA
TIHACDAADRAALEAVLATVPA--DEPLTAVLHTAGALGDAVIESLTPAGLAGVLRPKVTAALHLHELTKGMELDAFVLFSSVMGVVGNGGQAAYAAANA
SLDALAGLRR-AQGLPATSVAWGVWDGGGMAG-A-AGEHTRRAGFPGMPAEQAVRALAPVVAGAQAPVVADIDWEVFTPRHAAG----------------
--R----PAPLLAEIAEARTA-LAAA--------RTAA--AG---DRPELASALAGL----TAAEQHRTVLDLVRAQAAVVLGHEAVAPGRAFKEAGFDS
LTVVQMRNRLAAATGLRLPTTLLFDNPTPNALAAFLRTQLVDDA------
>tr|A0A0A0NM31|A0A0A0NM31_9ACTN Uncharacterized protein OS=Streptomyces rapamycinicus NRRL 5491 GN=M271_46390 PE=4 SV=1
----------------------------------------------------------------------------------------------------
-------------RAAAHRALALVQSWLADERRSRLVLVTRGAVGVRGEPVADPACAAVWGLVRSAQSENPDRF-LLLDLYDQEAS-----FAALPQAL-
-SGDEPQMAVRGGAVLVPRLARVPAARQAPVATPLWDPEGTVLITGATGVLGSLVARHLVAHGVRHLLLTSRRGGEATS------AAELVAELTASGASV
SLAACDTADRAALARLLATVPAE--HPLTGVVHAAGVLDDGVIGSLTPERVDTVLRPKADAAINLHELTEDLPLSAFVLFSSAAGVFGGSGQANYAAANA
FLDALAQRRG-ARGLPAVSLAWGLWAERSMTGHMDDVERLNRAGVTALSSEEGLALFDAATARAHARAARAGDPGPGEGADASGGGHPESV-TDVHPEVT
TDHPLLVPMRL-DT--AALRVQASLGVPHLLRGLVRVPARATGAGGVEPIGQRLNGL----SAREQTQALTELVRTHAATVLGHDLVEDDHAFLELGITS
LTAVEIRNRLNLATGLNLPATLLFDHTTPAALAAHLRAQLVT--------
>tr|A0A0C2BEW6|A0A0C2BEW6_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. 150FB GN=QR77_03295 PE=4 SV=1
AWRYRVTWRTGTPAS--QPLPATWLVVVPEGWAAGAVRALTARGAQVVEHVVSAD----------------TDRERLAAALAE-QPRPDGVLSLLALAEQ
PHPH-----HPGLTTGLALTTLLTQALGDARWAVPLWCLTQGATSAFGGEVHHPAQAAVWGLGRVIGLEHPEFWGGLVDLPAEYDE---RSAATLCDVLA
DGGDEDQWAVRAGTARVRRLSRAQAEGT--PARRAWRPNGTVLVTGATGAVGPYIARWLSGAGAGHLVLAGRRGADVP------GAAELAAELAVSGTRL
DHAVCDVTDREAVAGLVERLAA-DGTPVRVVVHAAALIQIASLAATSLTEFEDVVHAKTAGAVHLAELLP--DLDAFVLFSSIAGVWGSGDHGAYAAANA
FLDAYAEHLR-GRGVPATSLAWGIWDTPNLAETALDMDRVRRQGLPFIAPDLAVTALQRAMDDDEAFLVADVDWARFAPV------------------FT
SAR----PRPLLDEV------------PE------VAALSR------QEVPAVA-P----VTAALSEAELVTLVREQVAAVLGHAAIDPKRAFRDIGFDS
LTAVELRNRLNAETGLRLPTTVVFDHPTVQAIARHLRAEL----------
>tr|M3C265|M3C265_9ACTN Type I polyketide synthase (Fragment) OS=Streptomyces gancidicus BKS 13-15 GN=H114_04122 PE=4 SV=1
GWRHRVEWRALPAPNSAAAIDGTWLLVVPAAAATAVRAALENRGVRTLTLTVASDD---------------MDREALLALLNG-AGTVTTVLSLLSLDTR
PQPD-----RPAVPQGLAGSLALVQALGDAGIGAPLWCVTQGAVGVGPEAPTAPVQAGVWGLGRAAALEHPKRWGGLVDLPAVATL---RTLAVLPDVLA
AGGEEDQVALREGKAYGRRLVHAPTGCK--TPARVWKARGTVLVTGGTGALGAHVARWLTDNGAEHVVLTGRTGD-GP------HVEELRTEVQSRGTRL
TVAACDMADREAVAGLVARLAE-DGTPVRSVVHAAGVSALGPVADAGPEDLEATLSGKVLGAEHLDAVLDPAQLDAVVYFSSISGTWGVADHAAYAAANA
ILDARAERRR-ADGAPVLSVAWGPWAGGGMIA--SVQGDLARRGVPVIEPATAITGLQQALDHDDTFVVADVDWRRFAEV------------------FT
SVR----GSALLREL------------PD------AATTTD------AGLREIA-A----LDPARRPAALRALVSTAVAAVLGHDALGDETAFKDMGFDS
LTAVALRDRLNRATALTLPTTVVFDHPSITALAACIEERA----------
>tr|A0A086GID2|A0A086GID2_STRSC Polyketide synthase (Fragment) OS=Streptomyces scabiei GN=IQ62_43650 PE=4 SV=1
GWRYRVEWRALPAPTR-AATGGTWLLAVPAPSVTETVAALEARGARAAVVIVDADH---------------LSRSGLGALLTS-VGAFTGVLSLLALDER
PHPQ-----RAAVPLGLAATLTLVQALGDTDIEAPLWCVTRGAVGCGRGAPTAPAQAGVWGLGRAAALEHPKRWGGLVDLPATGPD---RGVDLLLDVIA
AGTQEDQVALRGGTAYGRRLVQAATGGK--AAARDWKPRGTVLVTGGTGALGAHVARWLAARGAEHLVLTGRHGE-GR------HLDDLRRELTPYGTRL
TVAACDTADREALADLVTRLAD-EGGPVRSVVHAAGVSVLGPVAETDVEDLSATLSGKVLGADHLDDVLDAAQLDAVVYFSSISGTWGVADHAAYGAANA
ILDARAERRR-ADGAPVLSVAWGPWAGGGMIA--TVQDDLRRRGVPVIEPAAAITGLQQALDHDDTAVVADVDWRRFAEV------------------FT
SVR----GSALLTEL------------SG------LRPATP--------LREIG-G----LEPARRTAALRTLVSTHVAAALGHAGVSAEAAFKELGFDS
LTAVALRDRLQRATGLKLPTTVVFDHPSISALAVHLDDRA----------
>tr|A0A066YH08|A0A066YH08_9ACTN Polyketide synthase OS=Kitasatospora cheerisanensis KCTC 2395 GN=KCH_74030 PE=4 SV=1
GWLAEPVWTDLPADTGDAPPPDRLLVLADAHGLAEQLARQRERGGHCHLVRPGAAYRH-GPDGSTVRPGSADDLRRLFADLDE---GYDTVLHLWNLDLP
SIDTGREQLTDCGTLGGYSLVALAQVLPSARPNGRLHIVTRGAQAVEDGDPVEPLGAPAWGVGRVLQQELVGHRGKLIDLAGTAEHPASAEAAALLRELA
V-EDAEEIALRGPRRATCRLARPALTR---PLPLRLRADGSYLVTGAFGALGRLLCRTLVKRGARRLILAGRTALPPREQWADRRVAFLRE-LEELGAQA
VPVPLDVTDETALADWLADHRRRQLPPVRGVFHLAGQVRDALVPELDRELFDAAYEPKVVGARNLHRQLRGEPLDHFVLFASIASVLTTAGQANYAAGNA
FLDALAHHRR-ARGLPALSIDWGPWA-TGMIEELGLVHYREARGMSSLPPAAGMAVLERVIGQDRAQLLVVVDWPVFQAW------------------YA
T-P-----PALVAELAAAAE-T-----------VQAAP---AG-----GFPAAFR----AADPDARRQLVAERFTELVAGVLRAERIDPAAGLNGLGLDS
LLAMELRARIHAEMGVSLPVVTLLSGDRVGELIERVHA------------
>tr|G2GPA3|G2GPA3_9ACTN Putative type-I PKS (Fragment) OS=Streptomyces zinciresistens K42 GN=SZN_36804 PE=4 SV=1
SWRYKTAWRPVSGTSV-PVLSGTWIVVVPES-VGDDLVRLDARGADAVTLTV--------------TEEDA-DRTRLAGRVQAGRHDLRGVLSLWAFDEK
PTET-----QPLVSAGLAGTVSLVQALRDLDATAPLWCLTRGAVATGPSTLTSAVQAQVWGVGRVAALEQSGVWGGLVDLPDTPDE---RALRRLCGILA
EPAGEDQLAVRAGGVVARRMVRASLGRTA--PARRWRPDGTVLITGGLGALGAHVARWLAREGAPHLVLTSRRGGDAPGA------DDLARELTGLGARV
TVAACDIADRDAVEALVTGLADQ-GDPVRAVMHAAVQAELAPLADATPDHFAALLGAKVAGAEHLDSLLGE-DVDAFVLFSSIAGFWGSGDHAAYAAANA
HLDALAERRR-ARGLAATSIAWGIWDAYDWDSLSTITDRAVQQGLPLLDPEAACTGLRQALDHDETFVIADIAWEPFATL------------------FT
SV----RPSALIREIPEAT-------------APDSAAPGDTTGHDAATLLRRLEGLP----REDRERELVDLVRFQAAAVLGHDQVGLDRAFRDLGFDS
LTAVDLRNRLKAATGERLSATVVFDHPTPAELAAHLHDRCF---------
>tr|A0A0N0GUJ5|A0A0N0GUJ5_9ACTN Polyketide synthase (Fragment) OS=Streptomyces chattanoogensis GN=ADL29_40220 PE=4 SV=1
SWRYEVTWRRSDDVKS-PSLEGTWLMVAEPG-TGER---LAAFGATVVPVDW--------------RPADT-DRAALAARLHAADGRIRGVLSLLGAEET
SHPD-----SPAVPSGLAGTLTLVQALGDAELDAPLWILTDNAVQVTATPAPSPAQAQLWGLGRVIGLEHAARWGGLVDVPRDLDD---RTAARLAAVLA
ADGDEDQIALRTDGAWLRRLAHAR-PAAG--PARSWTPRGTVLVTGGTGALGAQVARWLAAHGAEHLVLTSRRGEAAPGA------PALRDELTALGSRV
TLAACDVADRDALAALLAGIPAD--CPLTAVVHTAGVADVLALDDSGLADLAYAAEGKVTGARNLDELLGDTPLDAFVLFSSNAGVWGGGGQGAYAAANA
ALDALAGQRR-ARGLTATSIAWGLWAGDGLADPG-GQDYVLRRGLRPMAASTAVKALVHAVEHEDTFVVADVDWERFAPA------------------FT
AS----RPRPLIADLPEVR-------------KLTADPE---PSGETTALAARLREVA----EADRADVVLALVREHAAAVLGHSAIAPRRAFRDLGFDS
LTAVEIRNRIGAATGLRLPATLVFDYPSAADVAEYLLAQVA---------
>tr|K9YIP4|K9YIP4_CYASC Beta-ketoacyl synthase OS=Cyanobacterium stanieri (strain ATCC 29140 / PCC 7202) GN=Cyast_0285 PE=4 SV=1
QWLYEIVWEKDTSISFPLNTPSRYLIFVDEKKQGEAWAELTSQGSQVYLVYQGESYRQE-ETTYYVNPKNKQDYQLLLDSLDN---KIEKIIYGWAINED
DDLHNINQLNDNNYLDCLPLIYLIQNLVNSNHHIKLWLITQNSQSITHTEKINPYGGSIWGLGKVISLEHSEYWGGMIDIDNQGV--SLPLLTYLIN---
HQEKETMTAIRNNSVFHCRLQHKTPDSYQE-PQVTVTSSGSYLITGGLGALGLETANYLISQGAKNLILVSRSQPSSSA---SQKISQWQ----QQGINV
IVKQGDVTEKESLAQIITDIRQS-LPPLKGVIHTAGVLDDGILATLSSEKIAKVMAAKVMGVNNLHQLTLDDNLDFFILYSSVASMVGSIGQGNYAMANS
YLDSFASYRQ-SLGLPAISINWGAF-SVGMAKAT--QESLTSVGIETIPPQKGVAMIGDLINYPHSTMVVKFNWDILSRK------------------F-
--------PQLSL--SPYLKGVV--------------SSSLTEDEKDETQTQLFHQLL-KADESGRITLLIDYLIGAIALILHIEKITPEDSLMDLGMDS
LMVMEAINHLKTDLQLMLYPREIYERPQISTLAQYLAQEF----------
>tr|A0A0D6AW02|A0A0D6AW02_9CHRO Malonyl CoA-acyl carrier protein transacylase OS=Geminocystis sp. NIES-3709 GN=GM3709_3570 PE=4 SV=1
QALYQIEWIEGETFPLISSLPKSYLIFVESY-LTEKLADLSKQGHNVYLVYQGKEYRQQ-NNCFWLGNK-QEDYQLLWQSLDNRAFGIEVIIYGWGLSNQ
EEKETI-NLRDSNYLGCLPVINLLQSLVMTSSQPQLWLLTNQSQWVTHQEKINPQGGSLWGLGKVIALEHPEYWGGIIDIEMDNLASSSPILQKILLEID
RRGDEKMLAIRGKNIYCPRLRQKQKESLTNLRAIGIESSTSYLISGGLGALGIQCANWLIRQGAKNLILLSRRQPSATT---RKQLEAWQ----KQGVNL
YLPQVDVTNYEELKTVFEYIKIN-LPPLKGIIHSAGVLADGILTTLSVDKLEMVMSPKVLGAWNLHRLSLDLPIEFFVNFSSVASLLGSAGQGNYSAGNG
YLDSFASFRH-SLNLPCLTINWGAF-DVGMAESK--QHSLTASGMELINVHEGIGLLGELINYPLSQLVMKINWEKIGKK------------------F-
--------PSLFN--SPYVKDTL--------------PV------DEETLNNLFVELT-QADKEEREILLVDYLTKSIELILNPGHINPDDNLIDLGMDS
LMVMEAINNLKTDLQLMLYPREFYERPTISALASYLSQEF----------
>tr|A0A0B5IHG1|A0A0B5IHG1_9ACTN Polyketide synthase OS=Streptomyces vietnamensis GN=SVTN_37280 PE=4 SV=1
--------------------APDLVVFADEGGLGARLAEAVARGGRCRLVRPGSRYRSGA--HVTVRPDSAADLRRLFDELG----SFGAVVHLWNLDLP
PLDTGAADLDGIGTLGGYSLVPLAQVLPEACPEGRLHIVTRGAQAVVPGEPVEPFGAPAWGIGRVLWQELTGHSGKLIDLDPAGGPG----AEALLRALA
-DDGECEIALRSGRRHLSRLRPPVGLTR--PLPLRLRADGAYLVTGAFGALGRLLCRTLVRRGARRLVLLGRTGVPERGAWRRRRVAFLR-ELEALGAEV
LVAAVDVTDTAAMEGWLAGRRAAGLPPVRGVFHLAGQVRDVLLPSLDREAFDAGYGPKVHGGYLLHRLLREEPVEHFVLFASVASLLTTAGQVNYSAGNA
FLDALAHHRR-ALGLPALSLDWGPWA-TGMIEELGLAHYRDARGMSSLAPEAGMAVLERVIGQDRAQLLVVVDWPVFLS------------------WYP
T------PPPLVSALAAA----A-------------AREVPAGQ--GGGL---LDAFR-AADEPARTALVTERFAALAAGVLRPELVDADARLGSLGLDS
LLAMELRVRVHAELGVSLPVVALLSNGPVSELTERLHAGL----------
>tr|A0A014MLM7|A0A014MLM7_9ACTN Polyketide synthase OS=Streptomyces sp. PRh5 GN=Z951_41235 PE=4 SV=1
GWRYRVTWKPLADSQS-ARLTGTWLVVAPDTADTDAVAVLAERGADVTRIAVDTG----------ADGRD-ELTERLRAALATDGIPFTGVLSLLALDGR
PHPRH-----SSVPAGVAAQLALVQALGDAEIGAPLWSATQGAVSVGADPLDSPEQALVWGLGRVAALEHGERWGGLVDLPGAPDE---RALARLVTVLA
GAEEEDQVAVRATGLLVRRLVRAPLAGAP--AVRAWKPSGTTLVTGGTGALGAHVARWLAGNGAEHLVLTSRRGLDAPGA------ADLRSELTELGAKV
TVAACDVADRAQVEALLADIPAE--HPLTAVVHTAAVLDDGVIEGLTPDQVDRVLKVKVDATRHLHELTRDLDLSAFVLFSSFAATFGAPGQGNYAPGNA
FLDAFAEHRR-AQGLPATSLAWGPWGEGGMAEGG-VGDRMRRHGVIEMAPRSAVTALQHALDRDESVLVVDMEWKRFVLAFTS-----------------
-GR----SRPLLHDLPEA-R---------DVIQDMAGDAEADG-AGAVALAQQLAG----VPEAEQERLVLELVRTAVAAVLGYDDVEAGRAFKELGFDS
LTAVELRNRLSAASGLKLPPTLIFDYPTPTVLARQLRTEI----------
>tr|A0A0A8EKB2|A0A0A8EKB2_9ACTN Type I polyketide synthase OS=Streptomyces sp. 769 GN=GZL_03707 PE=4 SV=1
SWRYRIGWQRLPEPAS-AALSGNWLVVLPTGGAGTAAVALEAAGAEVTEVELPAE----------TDPG---------AVAELSGAAPEGVLSLVALEGT
P-------------VGAANTVSLLQALGTAGIDAPLWCATRGAVAVAGEGPDSPVQAQVWGLGRVAALEHPQRWGGLIDLPVDADD---AARRRLVGVLA
GAGDEDQLAVRAAGLYGRRLEHAPLADRA--PSRAWRPSGTVLVTGGTGPLAAQAARWLAENGAEHVLLAGPVEGVAGGE------AALEAELANAGARV
TIVPCESDDRATLEKLLATP-------PTAVVHAPTVLDQAPLAETTPAEFAAVVDAKAAMAAHLDELLDAHAPAVVVFFSAVAGVWGSGRQGAYAAGNA
YLDALAQRRR-ARGLPTTSVAWSPWDGGADTEDG-FLDFLRRRGLRAIDPALAITALQQVIDHDETFVLADVDWERFVAGFTA-----------------
-VR----PSPLIAGLPEV-R---------RIQAEE---GETAG-AEGSVLAQRLAG----KTDLERDRIVLELVRDQVAAVLGHEAVEVGRAFLELGFDS
LTAVDLRNRLNAATGLKLPATLIFDYPTATALADYLKTEV----------
>tr|A0A0F7FXR1|A0A0F7FXR1_9ACTN Hybrid polyketide synthase and nonribosomal peptide synthetase OS=Streptomyces xiamenensis GN=SXIM_40840 PE=4 SV=1
--------------------AGRHVLFADAGGVAQRLAALIEAGGEALLVRPGAAYGLDRARTATVVPGSADDLRRLLADLGPVD----GVVHLWNLDRP
ALADPRGRFADIASTGAYALIALTQALLADHGGTPVHIVTRAAQCVLPGEPVEPLGAPAWGIGRVLWQELAGRGGKLIDLAADGGVE--EDASALLRELA
DAEREDEIALRAGERHTSRLVAAEGLSR--PLPLRLRPDGSYLVTGAFGALGRLLCRTLVRRGARRLILVGRTRLPERERWADRHVAFLK-ELEALGAQP
ILAPLDITDEDALAGWLAGYRRAQGPPIRGVFHLAGQVRDTLVPEMDREVFDAVHDPKVVGAALLHRQLSGEPLEHFVLFASVAAWLTTAGQTNYAAGNA
FLDALAHHRR-AQGLPALALDWGPWA-TGMIEELGLDHYRNSRGMSSLAPEAGMAVLERVIGQDRAQLLVVVDWPVFMS------------------WYA
-S-----PPRLVTELAAT----------------AQGPGSE---GDGS-F---LDAFR-EATADKRRLLLTERFTTLVAGVLRAEQVDPAVSLNLLGLDS
LLAMELRARVVAEVGIALPVVALLSSAPAGDLITQLHE------------
>tr|A0A0C1YD43|A0A0C1YD43_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. 150FB GN=QR77_03210 PE=4 SV=1
GWRYREAWVPLAVPD---VVPGRWLVVVPAALEREPWVS------RVVTA-MGPSAE-----VMVCHAADRASLGAELTAVAGAGGPLAGVLSLLASAD-
--------------AAPEPTLALVQAVLDAGMTASVWAVTRGAVSASGDRVPMPDQGAVWGLGRVAALEHPGVWGGLVDLPEEADA---RVAEWLAGVVS
GDTGEDQVAVRSAGAFGRRLVRAPAEGS----GGSWPTSGTALVTGGTGGLGRCVARWLVGCGTEHVVLVSRRGPDAEGA------GAARAELEAAGARV
TIAACDVADRDALARVIEGIPAD--VPLRTVIHAAGAVADVPLESLTPEGLRSDLRGKATGARHLDALTRDMTLDAFVLFSSGAAAWGSGGQAGYAAANA
VLDALAFHRR-ARGRTATSVAWGAWDGAGLLAVPGRRDKLSRLGVMPMRPELAIAALERALRDDETSVVTDTDWARFVPA------------------FT
AV----RPSPLLSGLAEAARA------------LDAGRR-ESGGSDADDAARRLADL----PARERRAVLLALVRDNAAAVLGHTRIDADQAFRDLGFDS
MTAVELRNRLVTATGLALPTTLVFDYPTATRLADHLLSHF----------
>tr|A0A0C1XER3|A0A0C1XER3_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. 150FB GN=QR77_03205 PE=4 SV=1
EWRYREEWVPLAVPD---AVPGRWLVVVPDRLEGESWVS------AVVTA-MGPRTE-----VVRCGGEDRTAFAGLLREALGDGTPFAGVLAPAAPAD-
--------------EAVPFALALVQAAIDAEAAAPVWVVTRGAVAVEGD--PVRGQGGVWGLGRVAALEYPRFWGGLVDLPEAVDA---RVAEWLAGVVS
GDTGEDQVAVRDTGVFGRRLTRAPLVGP----GGSWSTSGTALITGGTGGLGAHVARWLVAHGTEHLVLVSRRGPDADGA------GLLRAELEAAGARV
TVAACDVADRDALARVVGEIPAD--APLRTVVHAAGVNGTVGVESLTPDQLHADSRVKAVGARHLDELTGALELDAFVLFSSGAAAWGSGGQAGYAAANA
ALDALAADRR-ARGRTATSVAWGAWDEVGMVVAPGHGDRLRRQGVVPMRPERAVAALERVLHDDETSVIADMDWSRFVPT------------------FT
AT----RPSRLLSALVEAERA------------TAEAP--LTGEEGESDFERHAAGL----SGRQRTLFLVELVRDHAAVVLGHQEIAPDQAFRDIGFDS
LTAVELRDRIAEATGLKLPTTTVFDHPTAGRLAEHLDALL----------
>tr|L0DP05|L0DP05_SINAD Amino acid adenylation enzyme/thioester reductase family protein OS=Singulisphaera acidiphila (strain ATCC BAA-1392 / DSM 18658 / VKM B-2454 / MOB10) GN=Sinac_7054 PE=4 SV=1
EWLYELDWIAKEPTARPDSSEGPWLILEDSRGVGQALRAHLARGIPCELVP-----------------CVDVDLEGLLKT-----KAYHGIVHLGSLDTE
VSAPSLAALDDAERKGVGSVLPLIQALGNLKPKPKLWLVTRGAQPTTSPGVQGLAQTPLWGMGRSIALEYAECWGGLIDLDPEAVD---GGAAALAAELL
DGDGEDQVALRSQGRYVPRLVRRKAPAPH-HGAPLVRPEGTYLITGGLGELGLQAARWLAERGARRLVLVSRRPLPLRTQWERKGVAAIQD-LERLGATV
VVANADVADPEAMAALFERLQA-TLPPIVGILHTAGFITNESTRDLDRQTLAAVLRPKVAGTLVLDALSRDLPLDFFGLFSSVASILGA-KEAHYAAANA
FLDAFAHVSK-AQGRPVLSVNWGPWAGAGMAASPDRMRAFHLLGFKPLEPDRAFRVLEGLIHEGRAQLVADVDWSGLKRLHAE-EG-----N--------
--------RHLLEKIEET-------RRPQR-------DLRPSG---RRELADWR-----NAPLEQRRETLVRYFRDRVAGVLRLDRIDPARPLNTLGLDS
LMAIELKGGVEADLGTILPLTSLMTGPTITELADQAIAL-----------
>tr|A0A0F5A2A6|A0A0F5A2A6_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. MUSC164 GN=VT50_36465 PE=4 SV=1
GWRYRVSWKPLTDVAD-GPLSGTWLVVVPASRAGDELVGLEGHGAHVVRVAVDER--D-------LD---ADVLAERLREVAAETPELGGVLSLLALDEE
PCPG-----HPALSGGYALTLVLVRAMVRADIPAPLWCGTRGAVSVGRDRLTSPTQAMVWALGRVAGLELPPLWGGLVDLPQSLDE---RGAARLAGVLS
AEGGEDQVAVRGSGVFVRRLVRSAPAV---GEETPWRARGTVLVTGGTGGLGGQVARWLVRSGAEHLVLTSRRGLEAAG------AAELKAELEDMGAEV
TVAACDAADRDALAAVLAAVPE--HQPLTGVVHAAGITIAASLLETGLADAARVVSGKVAGAVNLDELLGDRELDAFVVFSSISGVWGGGSQGVYGSGNA
FLDALVEQRR-ARGLAGTAVSWGPWAEGGMATRDDAGEQLARRGLPAMAPQLAIAALERAVAGDDGVVVVDVDWERFAPSFTAV----------------
------RPSPLLGDLEEALETKGEG--------------DESADAAGAQLRERLKPL----TEGERDRALLDLVRKHAASVLGYELVEPNRAFRDLGFDS
LTAVDLRNRLAAETGLTLPATLVFDYPSAATLAAQLRTEVLGASSP----
>tr|A0A0J8C1S0|A0A0J8C1S0_STRVR Polyketide synthase OS=Streptomyces viridochromogenes GN=ACM01_26010 PE=4 SV=1
--LFETRWQSRPIADE-PPAPGSWLILADESGIAAELVERLGTSVPHVVARRGDEFTTEGPGHYVLDPSDPQHLARLLDEAFA-NEPPERVVQLSALDAP
AIE-DAGTAEEAARLCCLSTLHLVRTIAGRGPAPRLFVVVRGSQAAGDSQVTQPQQALAWGFGLAVAQEHPELRTTLVDLPATDG------ADALWTQLR
HADDERLVALRGTGRLVPRLTRTRPDDAG---HGATTPDGVYLITGGLGGLGRVVAERLVRRGARRLALMSRSAPTAN---AMGWIHGLE----ERGVTV
HLAHADVADRTGLTAALDAVRR-ALGPITGVVHAAGVLDDATIGNLTDERVLRVLAPKVLGTALLTELTPEA--QDFVLFASAAGLLGSAGQSPYSAANA
FLDAWAHHLA-HADRRALSLDWGAWSGVGMVAESGVRAETGRPGLVAFSAQDGGELLERVLGTARRQLPMALDWELLALDA----------------DAA
------RSRPILADL-------V------------TAP---TGTPGTDDLVDKVF---AASTDTERAVRLEAYVRARVGEVSGAVQVSATTALKELGLDS
LMLVRLRNAFARELGVELPAATVFSAADIRGLAQALSTALPERD------
>tr|A0A0G3AUW2|A0A0G3AUW2_9ACTN Polyketide synthase OS=Streptomyces incarnatus GN=ABB07_37695 PE=4 SV=1
--LFETRWHPRPVAQE-PPVQGSWLILADDTGMADALGERLGSSVPHVIARTGSAFAAEGPGRYVLDPADPDHLARLLAEAFA-GGPPERVVQLTALDAP
PIG-DAGSAEQAARLCCLSTLHLVRALADRGRAPRLFVVVRGSQAAGDSSVTHPQQALAWGFGLAVAQEYPELSTTLIDLPPTDG------ADALWTQLR
HADDERLVALRGTGRLVPRLARTRPDDGG---TGETSVDGVHLITGGLGGLGRVVAERLVRRGARRLALMSRGTPDAE---AGNWITSLQ----ERGVTV
HLARADVADRESLTAALDAVRH-ACGPIATVVHAAGVLDDATVANLTDERVLRVLAPKVLGTTLLTELIPEA--RNLVLFASAAGLLGSAGQSPYSAANA
FLDAWAHHLS-RSDRRALSLDWGAWAGVGMVAGSGTRAETSRSGLVAFSPQEGGELFDRVLATARRQLPMALDWEMLTLVP----------------DAA
------RTRPILGDL-------V------------TVP---SGTAASDDLVRKVF---AATTDDDRATWLEAYVRARVGEVSGVADVSATTALKELGLDS
LMLVRLRNAFVRDLGVELPAADVFAASDIRGLARALAEGLPEQG------
>tr|A0A0M8VPX2|A0A0M8VPX2_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. MMG1121 GN=ADK64_03130 PE=4 SV=1
SWRYKVTWRPLSTPPAIGRLAGTWLLAVPAPLVAEAAEALTRSGAQVVPVEVDCA---------TVE---RAALAQTLAAASPEPSPIAGVLSLLGLDEA
PHPD-----HPVVPQGVAATLALVQALGGSAIDAPLWLATRGAVSVAGTDLTSPAQAQVWGLGRVVGLEHPERWGGIVDLPMELGES---TGQRLAEVLG
GTGGEDQLAVRRSGTYIRRLVEAPQTAKPRANPTAWQPRGTVLVTGGTGALGSQVARWLAKSGAEHLLLVGRRGAEAPGA------EALRAELHALGTEV
TIAACDVADREALARLLAE------HPPTAVVHAAGVGQLTPITDTTLDGYAEVLGAKVGGAVNLDELLAPDQLEALVFFSSNAGVWGSGGQGAYGAANA
FLDALAQHRR-ARGGHATSVAWGSWGGAGMAVEEGADAHLRARGLRPMDPDLAIAALAGALDQDETTVVADVDWARFVP------------------LFT
SARS----RPLIAEL------------PAVRALLEE-PEEDSGSG-DAALRQQLAALSA----TGQADLLLALVREQAAAVLGHSTVAAGRAFRELGFDS
LTAVQLRNRLSARTGLRLPTALIFDYPNATALAGHLRDQI----------
>tr|B4WHZ1|B4WHZ1_9SYNE KR domain family OS=Synechococcus sp. PCC 7335 GN=S7335_3862 PE=4 SV=1
DWIYTVEWQPTAVVDSPLAAGDHWLILGEDAARLKAIARLLEQAQNCTLALLGKAQQQSE-AYLEIDREHPESFHTQVQR----ASSWRGVLYFSGSD--
------------VEQSCKGALYITQALVSCNLSTRLLFVTDRAQAVLGDDSLNVAQSPLWGLGRTVALEHPELNCVCLDLDSTASEQ--QVLSSLLAEIY
QDSRESQVAYRNGKRYVARLTRPIQPAPASSKPIAIRANATYLITGGAGALGLQVAQWLVDQGARSLILVSMKPQF---KKIQQHIDRLR----QSGVDV
KMLHTNLLDRERLQRLVHTLQS-TSAPLKGLFHLAGEIDDGVLQQQSWITFECVLSAKVTGTWNLHQVTQDMSLDYFVMFSSVASLLGSVGQANYAAANS
FLDAIAHFRR-QQGLPGLSINWAAWAGSGLADTPEVEQRLKRAGIPLIEPETALEILDWLLSSTEAQILPGQNWQMAHVQTSL------------LTAIE
S------TALKSRK----SKRSLEHSSQP--TQQSPRPSSQ--ESSKSHVRSTI----QADLKVGNTTALIQHLQDQLAIVLGQAAVDQSADFTDLGLDS
LTAVEFRNRLQTSLKCSLPATLVYDYPTLAQLTDYIASLL----------
>tr|A0A0F2T5L0|A0A0F2T5L0_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces rubellomurinus GN=VM95_33085 PE=4 SV=1
-PLYAVRWTALPHPAQP-AAPGAWAVLGD-GGLA-----------------PVPD------------ATRHSDLAALARALDDGLPAPAVVVLPWPTAET
PGLP----APEAVHAAVARALDTVQTWLADLAATRLAVVTRGAVSVGDDDVRDLAAAAVGGLVRSAMSENPDRIV-LVDLDDDPASVP--ALAAAT-ATA
ADTGEPQLAVRAGTLYAPRIARSTPGDAA---RPAFDPDGTVLVTGGTGALGALAARHLVTAHGVRRLLLTSRGPAA--PGAAELAAELT----ALGATV
ELAACDVADRAALAALLAAVPA--AHPLRAVVHTAGAVDDGVIAALTPERCGPVLRPKVDAAVHLHELTHGLDLTAFVLYSSVAGVIGSRGQANYAAGNA
FLDALAQHRR-AAGLPGVSLAWGLWEESGLMREDTDRHRIDRSGVLPLSAAQGLALFDAALGRPEALLAVRLDLTALRR---------------------
-----------FDELPVILS----ALVPARR---------RAGGEEARRLAQRLAGR----PEAEQVQLLTDLTRRQAAVVLGHETVGADRAFTELGFDS
LTALEMRNRLNTATGLRLPATVLFDHPSATALARYLRTEL----------
>tr|D9WB22|D9WB22_9ACTN Modular polyketide synthase OS=Streptomyces himastatinicus ATCC 53653 GN=SSOG_00528 PE=4 SV=1
-SLFRVEWAPVAEGTDA-G-PSVVAVVGD-GGLS-----------------GGLR------------DVGCADLAALA---VAEAPMPDV-VLAEVATER
PGDG----VVDSAHATVAQTLGLVQRWLEGFAGSRLVVVTRGAV-------GDLAVASVRGLLRSAQSEHPDRIT-LLDLGDGAVSGA--VLS-----RA
LAQSEPELAVREGRLAVPRLARVGVPDAV---ARVWDGPGSVLVTGGTGGLGAVVARHLVAERGVRDLLLVSRGMAS--PGAEDLVAELV----ESGARV
EVVACDVADRDALAGVLA------GREVSAVVHAAGVLDDGLMGALTPGRVDAVLRPKVDAAWHLHELTRDLDLSAFVVFSSAAGTFGSAGQGSYAAGNA
FLDALVEYRR-GLGLPGVSLAWGPWDQDGMV-GEADRERMHRSGFPPLSVEQGVALFDAAVGAGEPVVLVRLDLSALRA---------------------
-----------RGEVSPLLR----GLIRTPF---------R--RAAVTGLAQRLSGL----GEVEQGEVLLDLVRSQVAMVLGHAAIDPGRSFRDLGFDS
LMAVELRNGLGAATGLRLPATLVFDYPTAQALVEHLFDEL----------
>tr|F5RC13|F5RC13_METUF Putative beta-ketoacyl synthase OS=Methyloversatilis universalis (strain ATCC BAA-1314 / JCM 13912 / FAM5) GN=METUNv1_01653 PE=
-HLLQRSWSACDRPRSV-VLPV-MLAAGGVRRLH-----------------PGQT------------LADPAHRRALLELLQQRDAFPDTVVWLAG--SA
---------CETVDADVRRFVSL-QLLVGAARALRLVYVGTPSA-----DDARCFHAAMSGLLKSLHLEAPRVSAVLLELDAASHDDPVAIAAALV-HPA
SPGHAPRLRVRDGRLEEARFGWLEAPATG---WQPT-RGATYLITGGMGALGRTFARWLA-RCGVHVALLGRS-PLD--EEGARVVAALG----GEGASV
VYVQGDVTDTASLAGALQQVRAT-LGPVRGVIHAAGVLRDAFFVKHGDDDWQAVLAPKITAARLLDQATREDPLEAFVLFSSLAGAHGNVGQSVYAYANA
WLDDYAELRA-QAVAETLALAWPLWRSDGMQAPPPVMQWMAERGLELLDAEQGIQALRAAMATTVAGVVCSGRREGVAR---------------------
-----------LMSVD---D----GAS-------------CDTAAAASSVPVA--------PAGDIVPALCSRLGDMLARA-CGSRVVPATPLQSLGLDS
IMVMDLNGELDQHF-SSLSKTLLYEADTVQDLASRIAAVE----------
>tr|C5B3B7|C5B3B7_METEA Putative beta-ketoacyl synthase OS=Methylobacterium extorquens (strain ATCC 14718 / DSM 1338 / AM1) GN=MexAM1_META2p0008 PE=4 S
-NIFEPVWLPDAA-----VGFGALLALGQDLGLT-----------------GGTT------------QERKDHLEHLWRTFKADGSLPAAVVADLR--HQ
---------PAVSPHGLERHLGLMALLKSVSKSCRMILICQG-----------PAASAAAAMMRSVHIEAPSLDFTVLETDGAEHPAYLF-VDAEA-KRT
AGGGVRHVRFIGGTPLVRRYAALDLPSRD---ADVR-SGDVVLITGGLGAVGLHIAKHLALHRGVRIALLGRS-RPA--EHSRAAVASLR----MAEGDC
SYWECDCSSGEDLTQTLADIRSR-MGPLTGILHCAGVLKDAFFTRHTDTERYEVLKSKALSARLLDEMTRQDPLRWFVLSSALAAVCGNIGQSVYGLSNG
WLDGFAEERN-SLTAATVAVAWPLWNTTGMQASERFLRRLQDEGLDLLEPDEGARLFAAATWSDRSLIVIKGDEERSSR---------------------
-----------ILGIK---D----AGI-------------PAGNTDDATLEPQGTAD----ANGGQEDRVLRYLIGTLSDV-TGERIEPDTPLEAFGLDS
LLVLEMSDRLQERF-PRIARTALFEARTLRALARLLIDEL----------
>tr|Q66VY5|Q66VY5_STRRM Rimocidin synthase (Fragment) OS=Streptomyces rimosus GN=rms PE=4 SV=2
GWRYQVTWKPLTGTSA-STLSGPWLALVPAGGADDEWTAALGDDAVS----------------VEADPADSRALTARLAELAAQGQEFAGVVSLLAARTG
EG---------VASGGAAWPDAAVQALADAGIGARLWYVTRGAVAVGRETDVDAAQAAVWGAGRVAALDHPDLWGGLVDIADVLDRR---SADRFRAVLS
GTGGEDQVALRSSGAFGRRLVRATADT----PSTPWQPSGTVLVVGGASGTGGLCARWLAGQGAQHILLAGPATPE---------ADTLPAELDGLGAEL
TRVTCDPADSDALLNALTAL------PPTAPLTAVVYADAEALSGDGEPGLAALHTAVENLAAVAEAAAGERPLDAFVLCSSIAGTWGAGGRGAEAAAGA
LLDALARRYR-ARGLRALSVAWGAWADTT---DDSLAAHLRVNGLPVMDAERALSALSRSAGTDAAVTVADVRWDRFAPAF------------------T
RNR----RGALFTDLPE--------ARAAL------AEPGNAGQGTATGLGARLAGR----PAAEQTEALLTLIRGEVATVLGFDAVPSGPAFKDLGFDS
LTAVDLRNQLATATGLSLPATLVFDYPTAEALAGHLRTELF---------
>tr|A0ACI1|A0ACI1_STRAM Putative modular polyketide synthase OS=Streptomyces ambofaciens ATCC 23877 GN=SAM23877_7117 PE=4 SV=2
SWRYREAWQPLDIPRA-GTLDGRWLLLHTEGVDTGHAEALLEAEPV-----------------DVTVPDDSWGLSELLRE-AAGAEPVTGILSLLADDRE
DG---------AVSVGLGATLTVVQALADAEVTAPLWCVTTGTVATHRDRIVDPAAARLWGLGRVAALEHPERWGGLIDLPIDPEPR---ATARLAA--V
LAGTEDQVAVRAEGVYTRRLLHAPAAE----LLPGKVAPEAVLITGGTGALGAETARMLARRGTRKLVLSGPGAPG---------AAELVAELADLGATA
VAHACDAADREGLAALLAEH-------VTGVVHAAGTDPALPLDSTSVPVLAEGLRAKAVGAEHLDALLP-D-AELFVVFSSIAGVWGSGGQAAYAAANA
HLDALVAARR-AAGRSGTAVAWGSWAQIGMAARDGVDEYLKRRGLRPMPPGLCVAALEHAIDTGDTVVVADVDWARFAPAF------------------T
SRR----PSPLLSALPE--------ATEAL------AG-GPAAEDQASAVRTLLAGL----PESEWARTVLDLVRRETAAVLGYEPVDADRPFKDLGVDS
LTAVTVRNRVAGALDLRLPTTLVFDHPTPSDVSRHVLSLVS---------
>tr|A0A0B5ESF4|A0A0B5ESF4_9ACTN SalB OS=Streptomyces albus GN=SLNWT_0686 PE=4 SV=1
SLCYEVSWQVLTGAPA-GTRSGQWAVLAPGGGTGGEAARLVALSAQV----------------IETAPDE----HERLAPALREHGPLDGVLSLLALDPA
AT---------T--------VALVSAANEAGSCGRLWTLTRGAVAVSSESPDSLAQSAAWGLGRVAALEHPDLWGGLIDLPASVDAL---AASRIVKVTH
PTPGEDQLAVRANGLFGRRLVAAPLPA----AAERWEPRGTVLITGGSGALAGHLARWAVERGARDLLLVGAEAPG---------ASALREELTGSGAQV
TFAAVDVSVREDLAALLAEH-------VDAVFHTAGVLDDGTLLSTGAERLARVRAPKAEAALLLDELTRAQDLSAFVLFSSLAGTLGSPGQSAYAAANA
TLDALAERRR-AEGLPGTSIAWGPWAGGGMAAEAGDRR-RGQGAVTALDPETALSTLGAVLDHGRTQFVAEVDWDRFVPAF------------------T
AVR----PSALLAALAP--------PTGST------EPATAQGAPDPTGLRGRLAGL----SVEGQLREVLELVRSRAAGVLGFGEVGAERSFRDLGVDS
LIAVELRNVLASVCGVSLPATVVFDYPTPLALAGFLRDEVC---------
>tr|A0A0F7W4D3|A0A0F7W4D3_9ACTN Chaxalactin biosynthesis PKS homolog to Erythronolide synthase, modules 1 and 2 OS=Streptomyces leeuwenhoekii GN=sle_61430 PE=4
GWCYRVAEEPVLTGAP-AVLSGRWVLVLPAGYEDDPWTGAL------------------------------AG-AEVERSTAGLAGPVSGVLSALALAEG
AP---------AVPTGLAATLDLLHDLASSDSGARLWCLTRTAGGA--------EQAMVAGLGRVAALELPRVWGGLIELPAEPGTG---TDGLVRA--L
AQDTEDQIAVRADGPRARRLVPVPRTA----APQPWKPRGTVLVTGGTGGLGAHLARHLARPGVD-LVLLGPEAPG---------AEELRAELLSAGASV
TVAACDVTDRQALAELLAGL------PPSAVVHTAGTSRSQPLAETGPAELAEVFAAKVLGAHHLDELLD-GPLDAFVLFSSIAGVWGSGGQAAYAAANA
YLDALAERRR-ARGLPATAVAWGPWAGDGMVD-DSTAEYLRGRGLRVLPPEAALTALERAVAEDHTLVVVDVDWGRFLPAY------------------T
SAR----RAPLFDRLTA--------TRPHR------AG-TARTTARNQAAQTEWAGL----SEAALPAAVLGLVRGQAAAVLGLEEVDTGRAFTAAGFDS
LMSIDLRDRLAAATGLRLPATLVFDHPDPEALTRHLCAELA---------
>tr|S5ULG9|S5ULG9_STRC3 Modular polyketide synthase OS=Streptomyces collinus (strain DSM 40733 / Tu 365) GN=B446_04650 PE=4 SV=1
--LFETRWQPRPEAQA-PPADGGWLILADGTGVADELARRLGDSVPHAVVRQGTAYGTDGPGRHVLDPADPAQWARLLDEAFAD-APPARVVQLTALDAP
PVTD-ARAAEEAARHCCLTTLHLVRALTGHRPAPRLFVVVRGSQPAGDTEVTRPEQALAWGFGLTVAQEHPELATTVIDLPAEGG------DDRLWTQLR
HADDERLVALRGSGRLVPRLARTRPDHD---GADPGQPDGVHLITGGLGGLGRVVAERLVRQGARRLALLSRGTPDAA---ATAFVRDLE----ERGVDV
HLARADVADRAALAAALDAVRAA-AGPVVTVVHAAGVLDDAVLANLTEERVRRVLAPKVLGTALLTELVPEAR--NLVLFASAAGLLGSPGQGPYSAANA
FLDAWAHHLS-LTGRRALSLDWGAWSGVGMVAGSGTRAETGRSGLVAFPPQDGGELFERVLASGRRQLPIALDWDLLALDP----D------------AA
------RGRPLLAD--------L-----------ITV---PAGGADTDDLVRRVF---GATTAQERAEWLETYVRDRVGEVSGGVDVFATTALKELGLDS
LMLVRLRNAFARELGVELPAADMFSATDIRGLAGTLAAALPERAA-----
>tr|Q93HH0|Q93HH0_STRAX Modular polyketide synthase OS=Streptomyces avermitilis PE=4 SV=1
--LFETRWQPRPPAQE-PPATGSWLILADETGVAVELAERLGSSVPHVIVRRGEAFGVEGPGRYVLDPADPQQLAHLLDEAFAD-GLPERVVQLSALDAP
AIGE-ARTAEQAARLCCLSTLHLVRTLA--DRAPRLFVVVRGSQAVGDTQVTHPQQALAWGFGLAVAQEYPELATTLIDLPSTDG------VDALWEQLR
HADDERLVALRDTGRLVPRLARTRPDDG---GHGELTPDGVYLITGGLGGLGRVVAERLVRRGARRLALLSRGRPGAD---AAGWIKGLE----ERGVTV
HLARADVADRAGLTAALAALRRD-AGPVAGVVHAAGVLDDATVANLTDERVLRVLAPKVLGTTLLTELIPEAG--NLVLFASAAGLLGSAGQSPYSAANA
FLDAWAHHLS-RTDRRALSLDWGAWAGVGMVAESGTRDETSRSGLVAFSPDEGGELFERVLATSRRQLPIALDWEMLALDA----D------------AA
------RTRPLLGD--------L-----------VTV---PTGGADSDDLVKKVF---AATTDHDRAVRLEAYVRARVGEVCGGVDVSGTTVLKELGLDS
LMLVRLRNAFARELGVELPAAAMFSASDIRGLVRALVAALPERDT-----
>tr|A0A0L8MWJ6|A0A0L8MWJ6_9ACTN Polyketide synthase OS=Streptomyces griseoflavus GN=ADK76_22730 PE=4 SV=1
---SRVRWRPAPGPER-EPAQGTWMILHHGDGIGELTGRQLSEGARVVEVRLGDSGEHQGGDRLVMAHADEDGFRRLWEAV---GEPVTGVLHLWNATEA
TGDG---AEESELRTGLHGCFAALKTLGERQRASRFLVVTRHAQPVVDGDTPVPARAALWGLVRTAAIEYPGLRPRLVDLDDAV--------EALAAELD
--DGPTEVGYRNGVRHEPVRVSEQWSRP---ARRSIRPGGRYLVLGGHGGLGLEVARRFAAEGAGLVALVSRRGAAGADP---SRLTGA----GSAACTV
VSYAADVTVPGQLRDVVARIRGE-HGELHGVVHAAGTLKDGLIRSTTVEDVTAVMRPKADGVRELAAAVDGTDLDFAVLFASVSGAFGNLGQGGYAAANA
YLDAFAHR----RGAPWLSVDWGLWGEVGMGTAV--ADQLRRRGVRPLGTAEALDALTGVLGGDARQVVIAHDGAEP-----HPD----G----------
--------TGPRPDAGD--R-HATEATPTRA------RPESDG--P------------DGVHAEAGRERVEDELERFLAERLGVTPFDRRVPLAEYGMSS
IMSVELSEELSRRWDLHLPATLFLEHGDFADLAQALTDRYG---------
>tr|V6KLY5|V6KLY5_STRNV Uncharacterized protein OS=Streptomyces niveus NCIMB 11891 GN=M877_03055 PE=4 SV=1
---TRIDWRPAPAGDT-DPATGTWVVLHNGGTLGERAARQLADGARVVEVGVGPAGT-HGPDHRTLTRPDEETFRRLWEEI---GDPVAGVLHLWNADAA
PDDP---GEETELRLGLYGCLAALRTLGERQRKSRFHVVTRDGQPVGTGDRPVPARAALWGFVRTAAIEYPGLRPRLIDIDQPS--------DTLRAVAA
--DGPTEVGYRRGVRHVPVRVRDRSAYTAPGAKGPIRQGGRYLVLGGHGGLGLEVADRFAREGAGVVALVSRSGAAPADD---DRTGAI----SARGCEV
VSYGADVTSPGALAAVVERFRAE-FGELHGVVHAAGTLKDGLIRSATAEDIAAVMRPKADGVRELAAAVAGRDLDFAVLFASVSGTFGNLGQGGYAAANA
YLDGFAQA----HGEPWLSVDWGLWGEVGMGTAV--AEQLRRRGVRPLGTTEGLDALIAVLGADLRQVIVAHDAGDV-----IEE----P----------
--------GAPFG---V--H--------TKA------PDDVSV--D------------VGPTGEGDGERVGEALEQFLTERLGVTSFDRETPLSDYGMSS
IMSVELSEELSSRWGVHLPATLFLEYGEFDELVEALTGRYG---------
>tr|S4XU45|S4XU45_SORCE Uncharacterized protein OS=Sorangium cellulosum So0157-2 GN=SCE1572_13250 PE=3 SV=1
--LYQVAWREAAPAPDVKTPSGAWLLLAEGSALGDAVARLRSAGAQCTTLALHQDAALRGGELRATASRVGEALGRAVAAAAARPQPLEGVVCLWGTSAA
TE--AGRSPADAAEALAAAGLAVAQALARQKVPSRLWWVTEGAQAVRRGEQVAAQLAPLWGLGRVVMQEHPDLGCTLLDLEPG----AEDAVEALWSEIT
RADEENQVAWRSGKRLAARLVEAPAAAALVAPAPAIPGSSTVLITGGLGALGLHVARWLEEHHVQHLVLAGRRAP---EGDRLAVVEALRA----AGTRV
TVAQADVADAAQVKALLDAIPEEL--PLRGVIHAAGVLDDGVLSQQDAERFAAALAPKVRGAWNLHEQTRHVPLAFFVLFSSAASLLGPSGQSSYAAANA
FLDMLAHARR-AEGLPAHSLNWGPWSGTGMAAEMDKQARLARRGIRGLAPEQALALLGQALARPEPELC-------------------------------
---------ALLLDVLALRQELSSGPVPPLWRALVAPHGGRAQARAAGGWAEQLGAL----APAARAAEVEAAVRAEVAKVLSLADVRTGRPFKELGLDS
LMAVELRNALAARLRVRLPATLAFDHPTVEAMTRYLLDLLSPDRESAKPA
>tr|M3BK51|M3BK51_9ACTN Acyl transferase (Fragment) OS=Streptomyces gancidicus BKS 13-15 GN=H114_28566 PE=4 SV=1
RWRYRVTWRPCAEPPAHDVLRDTWLIVVPAGHEDDPLVRVGAAEARVLVA-GEAEA-------------ERDRMADLLRQHS-EDTVVGGVLSLLALDES
PWS-----PEGVLPTGMVLMTALLQALGDAQVEAPMWCATRGAVTVRGDPLLSPLQAMSWGLGRIAALEYPQRWGGLLDLPEQFDA---RAARRLAAALS
GTLEEDHLAVRPSGIFARRLVRAGEGP---RPGGVWKPSGTVLVTGGTGGIGGHIARWLARGGAEHLVLVSRRGPEAPG--ADDLVAEL----AELGTPA
SVVACDVSDAQAVRRLVDDLP--GGGTLTAVFHTAGIIDDGLIDALTPQRAHDVLRPKADAALALDAATRHLDLNAFVLFSSMAGTLGGPGQGSYAAANA
HLDALAARRR-AEGLPATSVGWGTWAGGGMVGEE-VAERLRRDGVPPMDPELAVASLQKALDEDEEFVVADVDWKLITVR--------------------
----------AFAALRELPE----PRTAVTAVT-DRTEQKETDAVDGPPLVKRLAAL----PPAERRAALLMEVRDEAAAVLGHDAVPEGRAFRDLGFDS
LTAVELRNRFAEATGLRLPVTLAFDHPTASALAAHLDAEL----------
>tr|A0A0Q8Z0J1|A0A0Q8Z0J1_9ACTN Polyketide synthase OS=Streptomyces sp. Root264 GN=ASE41_05755 PE=4 SV=1
GWRYRVAWRPRTEQPARHELANTWLLVVPAGYEDDPLVRIGDAGARVLVV-GGPDA-------------ERDRMADLVRALA-DGVEVGGVLSLLALDES
PWS-----AEGVLPTGLVLTTTLLQVLGDTRLEAPVWCATRGAVAVRSDRLTSPLQAMTWGLGRIAALEYPQRWGGLVDLPGTLDD---RAARRLIGALS
GTLEEDHLAVRASGLFARRLVRAGDGP---RPEGSWRPSGTVLVTGGTGGLGRHVARWLARGGAEHLVLASRRGPDASG--AAELVAEL----AESGTQA
TVVACDVSDAEAVRRLVDDLP--GGGTLTAVVHTAGIIDDGLIDALTPQRAHDVLRPKADAALALDAATRHLDLDAFVLFSSMAGTLGGPGQGSYAAANA
FLDALAAARR-AQGLPATSIGWGTWAGGGMVGEE-VAERLRRDGVPPMDPELAIASLQKALEQDEEFIVADVDWKLITAR--------------------
----------AFAALRELPE----ARVPLST----DSGEKKADSVDGPPLVQRLAGL----SPAERRAALVTEVRAQASAVLGHDAVPDGSAFRDVGFDS
LTAVELRNRFVEATGLRLPVTLAFDHPSAGALAAYLDAEL----------
>tr|A0A086K178|A0A086K178_TOXGO Putative type I fatty acid synthase OS=Toxoplasma gondii GAB2-2007-GAL-DOM2 GN=TGDOM2_204560B PE=4 SV=1
--LWSVEWRASHQQPVPVDHSTNWLIAGVHPAVQSQLEEFFLPGAKVVFCAPS------------VV---ATDVRRLLQ-----QEAWNGIIHIGGVTAS
ISE----------MECLSDVLVLLQAVIDWPRLPAMFLVTRGACCEATEHSLAPVHSGMRGLFRTAKAELEALWNRYINIEPSSDKQTVEELRQVFSEPS
KPFYESESLLRDGELLLPRLVPASLEDCGDGNALAEAMTGTIVITGGLGGIGLVLAKWLTGQEARAVVLVSRTGTPSAEVQRSEDWHLLQSR-RQHQTRI
VTASCDVGDREQVKLLFRSLRAVELPPIRGIFHAAGVLRDCPIQKQDAETLASVFRPKSQGAWNIHNALEEEGLKVFLMFSSIASLVGNPGQANYAAANS
SLDALASYRR-CRGLAGHSIQWGPWIEQGMAAEL--GERLERAGFRGISNKVGVEVTEAVVSQGGDFVVAEFIWPRFVMRYRG-----------------
-C-----LPAIFEEQTRSVTVRMRDERSSRQ--------AAGPEMHQES---AF----ASMAPDELRALIQATVSGAAKQVLGTEEPPADAPLQALGIDS
LGAVEFRNAVQDAFDIRLSATLLFDYPSVQAVSDHLWSMVR---------
>tr|U6GPI9|U6GPI9_EIMAC Type I fatty acid synthase, putative (Fragment) OS=Eimeria acervulina GN=EAH_00065030 PE=4 SV=1
--LWKVKWVEGKTGHMKQGRALQWLAYGVETETACSMQRVDIRGERCNGCDA-----------------------DGVK-----LDEWDAVLHFGGACQC
WDGA---------VDYTADVLALLQGIANHTEIPPIVIVVAGAFAVRPGQAAHPLLAGVRGLCRTARLEMEATANRLIDLESTGQQAAHEMIHQVASTAG
GRYVMTEVAVRGGRMFTPQLTFSDIRLLRAGDR--VGQGETCIITGGLGGLGLVVALWLAGNGAKTVILLSRTGTPPREGTTAELWQQLTEK-C-RRTEV
IVQQCDVARVSDIEELFARIESHFVKPLTGIFHSAGVLVDKPLLQQDRRSVELVFNPKVEGAWNLHKCLGAEQLKYFVMFSSSVGLLGNAGQANYAAANC
CIDELALYRR-SRGLTAHSIQWGPWVEQGMAAQL--QGRFAKAGFGGISNALGLLTLNATLQQNTETVVGPVYWGRFFPRYRF-----------------
-A-----TPKVFEEIGMLETTASKTAATSSY--------RSGPRVEATQ---QA----NAGKQKDKRKHIQQVVMQAAKSVLNVSGVTLEAPLQELGIDS
LGAIEFRDAIQAALNVRLSATVLFDHPTVDALTKFLLQEIS---------
>tr|A0A0G4EHS9|A0A0G4EHS9_9ALVE Uncharacterized protein OS=Vitrella brassicaformis CCMP3155 GN=Vbra_7413 PE=4 SV=1
--LWEVTWKQAEPSKEAAAAEPRWLLFGVPAAWKKVLSRLVERESRLIAYGET------------PD---AMDEKILAD-----KNKWDCVLHMGSLEKR
SDP----------VVVVSEALRMAQVILK-NVLPAIWLVTRGTQLALPDLPEIPRHAGLWGFAKTARLELENNIGTCVDIDPTSPDTVD--IEQMAIELG
KRWSKEEVLARSGKIKPPLHTFDVIIQIDEATPAGRQTDGCYVITGGLGGLGLLVADWLVEEGAKNVALLSRRGKPTDAVAASDLWTKLTAP-EPHGRSK
ATIYCNVSKKDECENLFADLKKLPKNPVRGVFHAAERLDDAALNNQTKDKVEKVYLPKVMGAWNIHELS--IPLDHFMMFSSVASLLGNFGQTNYSAANS
CLDALALYRK-SQGLPCQSIQWGPWIEQGMAAEL--KQHLDKVGIRGITNELGLRVMGDVMRQGGPSVVGGLKWAIFLRRYG------------------
-D-----MPAFFSEIPMAASAESGG-----------------GKVDLK-----------AI----SKLDLSGLLSSLAQQVSGSEKPPIDAPLMDLGLDS
LGAVEFRNSIAEVTGVRVPQTLVFENPTIEVIADFILDTAH---------
>tr|A0A014KX73|A0A014KX73_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. PRh5 GN=Z951_46245 PE=4 SV=1
SWRYQTTWKRLPTPPTRPDLSGTWLLIIPAGAVATAAQALTGHGATLRHVL----------DTRTVHR---DALADHLTRLAT-EGEPVGVLSLLALDEE
PHPS-----YAAVPSGLAATAVLVQALGDAEIPAPLWCLTQGAVAASGDPLPSPRQAQTWGLGRAAALEHPRRWGGLIDLPTVIDH---HTADRLAALLA
PGGPEDQTAIRATGSYARRLRRAGTPTT---APRTWQPTGTTLITGGTGGLGAHVARWLARHGAPHLHLISRSGPDAPGA--TQLAQEL----TDLGTTV
TITACDASDRTALQHLLDTIPAE--HPLTTVIHAAGTSDTELIADLEPERLQHVLGPKALAAAHLHELTQGLDLSAFVLFSSGAAAWGGSRQGAYAAANT
YLDALAEHRR-ARGLPATSLAWGPWGDAGMAADETALAFYGRRGLSPLSPELAVASLQHALDHRDTTTVADIDWEKFPTAFTAQR---------------
---P----SPLLDELVTAA------ENPTG--------RTAGTSTDTTSLQQRLS---A-ATPEQQHQFLLERIQSLAASILGHDAIPPGQPFQELGFDS
LTAVELRNQLATATGTDLAPTLVFDHPTPNALATYLRAEL----------
>tr|A0A0B5FB63|A0A0B5FB63_9ACTN Acyl transferase OS=Streptomyces albus GN=SLNWT_7326 PE=4 SV=1
SWRYRIGWQPVAGADS-PALSGTWLLAVPDAPLVEEVAGWSGAGATVVTVPVGDEERG-------------ALAARLTEAL--GGGAPGGVLSLLALNEA
PHPAHP-----EVPAAVAATLALVQALTAAGIEAPLWCLTRGAVSTGGAHLAAPGQALLWGLGAVVALEHPQRWGGLVDLPAQRDAY---AGELLVAAL-
GQDGEDQLAVRPSGLLARRLRRAGADA----ATEGWRPRGTVLVTGGTGGVGAQIARWLARNGAAHLVLAGRRGPEAPGA------EALEAELAELGAQV
TIAACDVADREALEALFDSLAEDGGSALTAVVHAAGALEDATVDALTVEQTARVLLPKVAGARNLDDLTRERGLDAFVVLSSIAGTLGAAGQANYAAANA
FVDALARRRR-GDGLPGVSIAWSAWADGGMLGAD-VAEQLRRRGVRLLDGEQATGILGRSVSAGDGLVVADLDWERFAPSLSATR------P--------
--------LPLLAEI--------APGDPAQASGA------EAEEAGGGALRARLAAL----DPADQDSALAQLVAEQAAAALGYAAIEAGRAFKELGFDS
LTAVDLRNRLGAATGLRLPVTLVFDYPTADDLAQLLREEL----------
>tr|G0Q416|G0Q416_STRGR Amino acid adenylation domain protein OS=Streptomyces griseus XylebKG-1 GN=SACT1_0942 PE=4 SV=1
SWLAEPVWTDCPPLPAGAARDHDWLVLADDGGTADAFAALAARGERCRLVRRGAAYTASDGAAFTVDPASDADLRRLLADLDRDGGPFRAVLHLWNLDAP
ALATDRASLTDHTGAGAYSLIALARLLSARGTGGRLHIVTRGAQPALPGEGPEPLGAPAWGIGRVLRQELTEHPGKLIDLDPRRQPGDRAEAAALLGEVL
S-DDEEEIALRDGGRRTSRLRPARELTR--PLPPRLRADGSYLVTGAFGALGRLLCRTLVRRGARRIILVGRTPVPAREKWAGRAVALLR-ELEALGAQP
VLATLDITDEDALTGWLDAHRRSGAPPVRGVFHLAGQVRDTLVADLDRAAFDAVHDPKTVGAHLLHRHLRDEPLEHFVLFASIASLLTTAGQTNYAAGNA
FLDALAHHRR-ARHLPALSLDWGPWA-TGMIEELGLDHYLHSRGMSSLSPEAGMAVLERVLGQDHAQLVVVVDWPVFLA------------------WYP
SS------PPLVAELAAA----A--APPA-----D--AASGNGFLDT---------FR-AADEETRRTLVGDRFAALSATVLGTDRIDPATGLGELGLDS
LLAMELRARIHAELGVALPVVALLSGTPAGELAAQLHDG-----------
>tr|D9WQ64|D9WQ64_9ACTN Modular polyketide synthase (Fragment) OS=Streptomyces himastatinicus ATCC 53653 GN=SSOG_05738 PE=4 SV=1
GWRYGVSWRPVRDRSA-GAPGGCWVVVVPAGEWSAGVVRLAERGVDVRLVELGAEAERG------------AVAEQLRAAVV--GASVAGVVSLLAVEGD
A--------------ALLRTAALTQALGDAGMGAPLWVATRGAVSVGSDGAVCPDQALVWGLGRVAALELPERWGGLVDLPESVDE---RALARLAGVLA
GGGGEDQVAVRASGVFGRRLVRASAAVSS--GGSWRPGGGSVLVTGGTGALGARVARWLVAAGAEHVVLSSRRGLDAPG------AVELRDELSASGARV
TVAACDVADRDALAELLASLPDE--LPLTAVIHTAGVLDDGVVDGLDAERVERVLRAKVASARNLHELTRDLDLSAFVLFSSLAATVGAPGQGNYAAANA
YLDALAERRR-AQGLPATSIAWGPWAEGGMAADDALERRMRRDGVPPMAPEVALTALQQALDHDDTAVVADIDWDRFLAEFTAV----------------
------RPSALFGELPAARP------VPAAA----ERP--TATGAGTGTLAERLSGLT----GTERAQTVLELVRTQVAAVLGHEAVVAGRAFKELGFDS
LTAVELRNRLNAATGLRLPATLIYDYPNATALADHLRTELL---------
>tr|A0A060ZDD0|A0A060ZDD0_9ACTN Beta-ketoacyl synthase OS=Streptomyces iranensis GN=SIRAN1030 PE=4 SV=1
NWRYRVAWKPVPDAAD-GSLSGTWLVVVPASRLVAEVVTLERHGADVVSLVDERDLDAE------------ALGERLRVAIA--DTALGGVLSLLALDEE
PCPGHL-----ALSSGLALTLTLVRAMADTGVEASLWCATRGAVSVGSERLSHPAQAMVWALGRVAALELPQLWGGLVDLPESLDE---RAAARLAGVLS
AEVAEDQVAVRGSGVFARRLTRSAAPAAD--GTAWRAR-GTVLVTGGTGALGGQVARWLVRDGAEHLVLTSRRGIEAPG------AAELREELEALGVRV
TVAACDVADREQLAAVLDAVPEE--LPLTAVVHAAGANGTGPLAETGLADAAAVVSGKVAGAVNLDELLGDRELDAFVVFSSIAGVWGSGGQAAYGAANA
YLDALVEDRR-ARGLAGTAVAWGPWAEGGMAAGD----QLARRGLPAMAPGLAIAALRGAVAGDDGVVVADVDWERFAPAFTIG----------------
------RPSPLLGDLPEVQR------ALANA-----GS--AEGTSAGSALRERLTGLT----EAEIDRTLLDLVRAHAAAVLGFDSVEPARAFKELGFDS
LTAVEFRNRLNVETGLVLPATLVFDYPSATVLADHLRAEVL---------
>tr|A4FDM8|A4FDM8_SACEN Modular polyketide synthase OS=Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 
ELLFQLDWLPLPTVPA-SSAARHWAVVGPDVF----VADL---------DSQGRSVDRY------------SDADELVESVD--SAEAAPEVTVLQVAGT
TAGGAASPAEEARDRVRVVTEQAESWLGDEFAEGTLVVVTRAAVAAGDDEVSDLVAAPVWGAVRALRAAHPGRV-VLVDLDDGG------SAAALAEAVS
--SAEPELLLRSGVALRPRANRVAATGGS--RPFQLTSRDTALVAGADGVVAATVARHLAAVDVRRFLLVSRGGDADLA------ARELRAELTAAGASV
ALVACDVADRDALAGLLAGHR-----PAAVVFAAGA----G-----------REALSTMDGALNLHELTLDAGLKAFVLLSSAAGTLGGAGSADDAAAGV
FLDAVARHRA-ARGLPALSVVFGPGEHEDWSV---------PAGVGRLTGREHAAMFDAAHLADRTSVALRPDSTA----VGSG----------------
------SLPPALRD---LID------VPVQA----DAP----DDGTVSELRERLAPLS----RDEQDRTLVELVRGEVARLYAMATVPSDRAFRDLGLDS
ATAVQLRNRLTATTGLDLPLTLAFDHPTPARVGRHLRSLLF---------
>tr|A0A0A0NSP2|A0A0A0NSP2_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces rapamycinicus NRRL 5491 GN=M271_45450 PE=4 SV=1
DALFRTRWVPQPSAPQ-PPRPGRWVLLGRHAP----FVGL---------RAIGTELGEH------------VDTVDLRAAVA--AGSPPPAVALLS----
-APA---------DTTEGVLRDVETWLASALSDALLVVVTQSAVATTGEDVPNPEQAALWGLARSLQAAHPGRI-AIVDLDAPDDE---TCAGALLAAVA
--SGEPQSAVRSGVVLLPRLERVALDMGL--GSVAFDPHGTAVVTGVDTRRGAAIARHLVTGGVRQLLLIAPPGQGG-R------AYELCTQLTDAGAGV
RLVECDLDNRTKLRRALAKATS----PLSVVVHAWE-AVDE-----------PSDGRVVAEARTLYELTRKADLTAFVLSSSTKGLLGAAGETTEAASAA
FLDAYAQHLR-MRGVPAQSIAWGPWEGETD------------ETTGALSSREALAALDAALGVDHAQLAMKLDPTA----VPTG----------------
------TASPLLQD---LID------VPART----ATV----DEAVTVALRERLMDTH----EADRDRLLTDLVREHLADLLGLHAVEPERAFTDLGLTS
VTVVELRNRLSEATGLRLPATSAFDHPTPVALGSLLRRELL---------
>tr|V4HWI5|V4HWI5_9ACTN Beta-ketoacyl synthase OS=Streptomyces sp. PVA 94-07 GN=B590_00370 PE=4 SV=1
DPLFHVRWQPLPPQAT-PSPSTPWGILGQDTL----LRPLEDAGSSPTSYE---------------------SLSDIG--------ETVPATVLLPV---
PEGGADDPPGRVHALFSSVLATLREWLADEFSAARLVVVTRGAVLTGGGDAPDPVAASVWGLLRTAQTEHPDRFVLL-DLDTGAGT---ETADALATALG
TG--APQLAVRSGTAFAPSLVRGTEPAPP---TRPIDTSGTVLVTGALGTLGRLTTRHLVTEGVRHLLLTSRTGPATEG------ADTLRAELAELGAEA
TLVACDTADRAAVAELLAAVPDE--HPLSAIVHVAGVLDDAVLEALTPEQVAAVLRPKVDAAWHLHELTRDLDLSAFVLFSSAAATFGNAGQANYAAANA
FLDALAGYRR-ARGLTATSMAWGLWAEASGMTDHTDLQRLARLGVTPLTSTAGLMAFDEALRLNRPAVPMGLDTRRLA-AADAA----------------
------SLPPLLAPYARATP------VRRRN-----AA--ATSPASATGLLDRLRSLT----AQQQLDTLLGMVKRHVVSVLGGASVRTQTSFKSLGFDS
LTSVELRNRLNKETGLRLPATLAFDRPNPAAVADFLQRELT---------
>tr|A9YLB5|A9YLB5_9ACTN AngAIV OS=Streptomyces eurythermus GN=angAIV PE=4 SV=1
AWRHKVVWKGLPTEET-ARLSGRWLLVLPEGGPADDIADVLRHGATVR--------------RLVADPVALG-RDGLAARI---SGTWDGILSLLPADER
PHPA-----HPSLDRATVGTVLLAQAVSDIGTGARLWTVTRRAVAVAAGEEPSTAGAQVWGVGRGIALELPTVWGGLVDLPDAPDA---RCLRRLAWVLA
AAGAEDQVAVRASGAYGRRLAPAGGAAG---EGRAYTPRGTVLVTGGTGALGGHVARWLAVNGAEHLVLTSRRGQDAPGA--AALTAEL----EARGVRV
TVVACDVSDCAALAALLDEH------PPTAVFHTAGVPHSGAFLDLRTDGMADVYGGKVTGARHLDELTRERDLDAFVLYTSGAGVWGSGGQTAYGAANA
ALDALAERRR-AGGLPATAIAWGLWAGGGMGEGD-GEEFLSERGLRAMPPESALESLGVALERGDTCVVAHVDWPRFARSFTA---------------FR
-------PSPLIGDLAGT-GGAG-ERY----------GDGEESTGDQG-FLARYT----ACGPVERREMLLDLVRRQVAAVLGHEEVPADQAFRDLGFSS
LTAVEAATRLGRAVGAKLPPTLVFDHPTAEAVGDHLAEVL----------
>tr|A0A0F7C8U1|A0A0F7C8U1_9ACTN Polyketide synthase type 1 OS=Salinispora pacifica GN=spr10 PE=4 SV=1
GWCYRVGWKRLERAD--DPLTGRWLLVTGPDP---LVEAALARGAQVQ--------------HLTVDPATAD-RASLGALLAAGGSGASGVLSLLGSDRR
PHPD-----HPDVSVGTTATLLLTQAVADAVPTARLWTVTRGALAVAPTEVPDEHQAQVWGLGRVAALELPQLWGGVVDLPVASDE---QIWDGLADVL-
-AGAEDQVALRGPAAYGRRLRRAPA-LP---PKRSYRPRGTVLVTGGTGALGTHIARRLAADGAAHLVLTSRRGADTPGA--ADLVEEL----RALGAEV
TVAACDVADRAAVADLLDGLPV--TDPLTAVFHTAGVAHSVPVTETGLPDVAEVFAGKVAGARNLDELTRGYDLDAFVLYSSNAGVWGSGGQSAYGAANA
ALDALAERRR-AEGLTATSIAWGLWGAGGMGEGS-AEAYLSRRGLRPMSPEKGVDALLAALDRDETFVVADVDWDLFTAGFTA---------------FR
-------PSPLIGDLPEV-RAVL-ADS----------TGQEGASIGSD-LLDRLA----AADREDCHRILLDLVRRHVAAVLGHEHIDPHAAFREIGFDS
LTAVDLAKRLKAAIGVPLPATLVFDHPTTMAVAEHLIGLV----------
>tr|A0A014NVA9|A0A014NVA9_9ACTN Polyketide synthase OS=Streptomyces sp. PRh5 GN=Z951_39950 PE=4 SV=1
GWRYQAVWKPLASASE-TTLSGTWLVFSEGRGVATVLDGLAGRGAHVVRVAVGAADDR-----EVIT-------ERLRVALDGAAVEPSGVFSLLGLDES
AHE-----SFEVVPAGLAATVGLVQALGDADVVAPLWCGTRGAVSVGRDRLVSPVQSMLWGLGRILEAEYPQRWGGVVDLPETMDD---RAMTRLAGVLT
AAESEDQVAVRGSGVFAKRLVRASAPEAT--AADGWRPSGSVLVTGGTGALGGHVARWLARTGAEHLVLTSRRGMEAE------GAAELKAELEALGARV
TVPACDAADRAALAAVLDAIPQE-F-PLTAVVHAAGVLDDGVVDALTARRAAGVLRPKVDAARNLHELTAGMDLSAFVLFSSAAATLGGPGQGSYAAGNA
YLDALALQRR-ADGLPATSIAWGAWAGGGLATGE-VGERMSRSGILAMPPELAIAALQQALDHDETFLVADIDWTRFEADSV------------------
-------DTPLFRQLRSARSTTT-G---K--------QLTESAAPGRGELHDRLAALP----AEKREGALRDLVRAQAADVLAHDAVASDRAFRDLGFDS
LTAVELRNRIGAATGLRLPVSLVFDYPTPTVLARFLNGEMF---------
>tr|B5X0I1|B5X0I1_STIAD Nonribosomal peptide synthetase/ polyketide synthase OS=Stigmatella aurantiaca (strain DW4/3-1) GN=dkxG PE=4 SV=1
-LLYERRWEPLALEGAGAGDNRPCLILADRAGFGRQLAEELRGGRTCFLAFRGQAFRRLDETSVEV-PGEPAALAEALRTLD-LPASVSDAILLWGLDGP
DAEMDVESLGQATLLGGGGALGLLQYLMGRGYSDAVWLITRGAQPVKPGPLPGMAQSVIWGMARPVAIESSELDCRCVDLDPRGEQ--LAQVGLLAQEIR
RRVADNQVAYRQG-RYVARLRRVEARKLLVERVQRFRPDRSYLVAGGLGRLGLLTAELLANRGARNIVLTGRDSVSPQ---AAERLERL----REQGVRV
EYRQADIADLGQLSALLREVGR-EMAPLGGVFHSAGVLDDGVLRQQSWSRFETVLRPKARGSWNLHVLTADMPLEHFVLFSSVASLVGSAGQANHCAATA
FQDALAHHRR-ALGLPGLSINWGVWAGDAG-ARVNVSEQARTPGFGVIAKQQGLQALEMLLAAQVAQAVAVIDWAAFGAGRP------S--------PYD
------------AD----LREKAGGR-------------T----AGRETF---LAKLT-SAPIAHRRKMLMDYLREQVAWMRGMESIDPAQGFSEMGIDS
LAALQLKNRLQGGLGVSLPATLVFNYPTTEKLAEQLMA------------
>tr|A0A060ZJ24|A0A060ZJ24_9ACTN Beta-ketoacyl synthase OS=Streptomyces iranensis GN=SIRAN149 PE=4 SV=1
DWFYRVTWQPAAMPEN-AGPEGRWLALLPRDGAGEVLLGLVAQGMRISRITVGD-------------------IDGLAERLA--GSAPQGVLSLLALDET
PDPDHPA-----MARGTLLTAATIRVLGEAGIEAPLWCVTAGAVATDADPVRNPVQSQVWGLGRVAALEHPERWGGLVDLPGMPDE---QTFVRMAAVLS
GGGDEDQIALRNPGVLVRRLVRAEPVSG--RAGGGWRPRGTVLITGGTGALGRQVAHWLAGNGAGHIVLTSRSGKNAPG--AMELADAL----IGRGVKV
TVAACDVTDRQAVSELVAGL-----PELTAVVHAAGVGAYRSLAESSAADIAGVMAAKVAGAAHLDEILGDRELDAFVLFSSVAGIWGSGRQSAYAAANA
YLDALAQNRR-SRGLAGTAVAWGPWGGGGLVSDRDVAGRLSRLGLDQLAPGQALTALGMALERDEPTVVADVDWARFAPAFTA-----------------
-N----RARPLIGELPE-VRQAL----------------ADDE-PAEVSLRDELAGM----PREQAAGVLLDMVRTNAATVLGLATVEPDRPFRELGFDS
LTAVELRTRLGAATGLRLPATVVFDYPTPVALAGHLGAGL----------
>tr|A0A060ZAR4|A0A060ZAR4_9ACTN Beta-ketoacyl synthase OS=Streptomyces iranensis GN=SIRAN146 PE=4 SV=1
DLYPRLAEAGYYGPVF-QGLTSVWRAVDPLDSAAEFLFGVAATGAPAVRVRMAG-------------------SDAVSVELA--DGAPSPHESLFRVTWV
PVPETGD-----DGAETVLVEATAEALGAETKPGRLVFVTRGAVAADGDDVTDPAGAAVWGLVRSAEAENPGRFAL-VDLDGDGTV---RL---------
-PVGEPQVAVRRGKVLAPRLARTA--AD--GEPVRLDPRGTVLVTGGTGMLGGLIARLVSAYGVRNLMLISRRGPHGPG--VDDLVADL----AERGARA
TVVACDAADREALAATLATI-----PALTAIVHTAGVLDDALLESTTRQRLAAVLRPKVDAAVNLAELTEDERLAAFVLFSSAAAVLGGAGQGAYAAANA
FLDAFAQQRQ-ARGAIVSSLGWGLWAPPSEMTGHLDAARLARAAMVPLTGEEGLALFDAALATGAAHTPARVNLATL---RRD-----------------
-G----AIPPLLSGLVARGRRAA----------------SASG-TADPGLAERLAGM----PEAEGSAYLLGLVRSHVATVLGRDDVDAGRAFKDLGFDS
LTAVDLRNRLGAATGLRLPATVVFDHPNATGLAGFLRAEL----------
>tr|A0A014KX73|A0A014KX73_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. PRh5 GN=Z951_46245 PE=4 SV=1
SWRYRVAWKHLPDPATAPTLSGTWLLLVPSG-LEEHVQALDAHGA---------AHEALSLDGVE---ARRDALAPLLSHL-PDGSTPEGILSLLALDQT
PHPD-----HPAVPTGLAATAAVVQALGQTPLIAPLWCVTQGAVAATATPLPHPHQAQIWGMGRVAALEHPHLWGGLIDLPADVDART---PARIAAVLA
PGQPEDQVAIRAT-ALARRLERAACPDT---APTAWRPAGTTLITGGTGGLGAHVARWLARHGAPHLHLISRSGPDAPGA--TQLAQEL----TDLGTTV
TITACDASDRTALRHLLDTTPAE--HPLTTVIHAAGLAENTPLAELDLPGIAAVLRPKALAAAHLHELTEDLDLSAFVLFSSGAAAWGGSRQPSYAAANA
YLDALAEHRR-ARGLPATSLAWAPWSDAGMAADEAVIDYYRRRGMRPLDTDLAIASLQHALDHADTTTIADIDWARFPAGFTAQR---------------
-------PSPLLSDLVA-------TASPGA----DATP-----DVDA-TLSSSLQRQLTTGSPAQQHQLLLHHIQTHAAAILGHDAVPPAQPFQELGFDS
LTAVEFGHRLSAATGLDLPPTLVFDHPTPKELADYLRERL----------
>tr|M9U897|M9U897_9ACTN Uncharacterized protein OS=Streptomyces sp. PAMC26508 GN=F750_6881 PE=4 SV=1
SWLTEPVWTDCPPLPAHAARDHGWLILADTGGVADAFAALAARGERCRLVRRGPAYTASDGSTYTVDPASDSGLRRLLADLDRDGGPFRTVLHLWNLDAP
ALACDRDTLRDHTGAGAYSLVVLARLLAARGGGGRLHIVTRGAQPALPGEGPEPLGAPAWGIGRVLRQELIGHPGKLVDLDPRRQQGDRADAEALLAEAL
-SDDEEEIALRHGGRRTSRLRPAEALTR--PLPLRLRADGSYLVTGAFGALGRLLCRTLVRRGARRLVLVGRTPVPPRATWAARAVHLLR-ELEALGARP
VLATLDITEEDALADWLDAHRRSGAPPVRGVFHLAGQVRDTLVADLDRDTFDTVHDPKTVGAHLLHRHLRDEPLDHFVLFASIASLLTTAGQTNYAAGNA
FLDALAHHRR-AQGLPGLSLDWGPWA-TGMIEELGLDHYLHSRGMSSLSPDAGMAVLERVIGQDHAQLVVVVDWPAFLAW------------------YP
S------PPPLVADLAA----AA---SPPR----D--AVSGNGFLDS------F---RA-ADPQTRRALVAERFAALAATVLGADRIDPAAGLGELGLDS
LLAMELRARVHAELGVALPLVALLSGSPAGELATQLHDG-----------
>tr|Q27W68|Q27W68_STRVO NigAVI OS=Streptomyces violaceusniger PE=4 SV=1
SWRHRVEWRPVPDTA--PTTAGSWLVVHPKSGWTDACVALGADGGQVYLLEL--------------DGDDREGLAALLRSRYAEETPPTGVLSLLALDEG
TPP------LPGVAPGLTGTLTLLQALVDAAVPAPLWCATRGAVSIDDSDPDAPHQAQLWGLGRVAALEHPDRWGGLVDLPASPDSL---DARRLCALLT
GACGEDEAALRPAGAYGRRLIPDPIGGR--APRRIWKPRGTVLITGAADGPAAHVARCLAADGAAHIVMLGPGGGDAPAA------VELKAELDALGTGL
TVADHAPADREATAHLLERVAQA-SGRIGTIVHTAASGELAPLMELTPRRLAEEHAHLDDTGRPLDELCGMGPEDTVVYFSTVAASWGSKDHGSYAAATA
CLDALARRDR-AEGRPTVSIAWGLWDLPYGGDATPHTERSRRQGLSPLDPRLALTALRQALDHDDPSVIADVRWERFAPLFTL-----------------
-A----RPSRLFDGVLAARQAIE----------TARGPVEDTVGDEASALRRELGAL----PEDERGERLLALVRAHVAAVLHYESVEPDRPFKELGFDS
IAAVELRNRLRAATGLSLPTTVVFDYPTPRTLAGHLLTEVDPGEAG----
>tr|Q7WTE3|Q7WTE3_9ACTN NanA7 OS=Streptomyces nanchangensis GN=nanA7 PE=4 SV=1
SWRHQIRWTPLP--P--PAVSSTWLLLVPTGHPAVRTVALTGHGAEVRPCPA--------------DPSSRAELAERL-TGLRGDDAPAGVVSLLALDER
PAD------HPAVPAGLAATVAALQALGDAGITAPLWCVTQGAVSTGHDDPSHPLQAQTWGLGRVAALEHPDRWGGLVDLPAEPDER---TEAQLAALLA
GGQAEDQVAIRAGGGALARRLVHTTSAR--TADQAWQPRGSVLITGGTGGVGALLARWAAERGAAQLVLTSRRGPNAPGA------AELAAELRGLGVAV
TIAACDAADPEAMRGVLDAIPAE--HPLSAVIHAAGVSEQDLIADVDDEHLNRMLAPKALAAWHLHELTRHLDLSAFILFSSVSASWGSGQQAGYAAANA
YLDALAEHRR-GLGLPTTSVAWGLWGEVGMA---DEVDAFRRRGIHPLDPGLAIASLQQAVERRETNAVAAIDWRRFLTGFTA-----------------
-L----RPSPLLSDLPEAAEARA----------EET----RPREDEADPLRRKLAGC----PPAEQHHILVRHVQAHAATTLGHDAVPPTKPFQELGFDS
LTAVQLRDRLNAGTGLRLPTTVLFDYPSAEELARHLHGLLVADAAS----
>tr|G2NTW1|G2NTW1_STRVO Beta-ketoacyl synthase OS=Streptomyces violaceusniger Tu 4113 GN=Strvi_3962 PE=4 SV=1
SWRYRVEWRPVTDA----APAGSWFVVHPKGGWTDACVALGADGGRVRGLEL--------------AEDDREGLAELLRSRSAEETPPTGVLSLLALDDD
ARP------LPGVAPGLTGTLTLLQALVDAAVTAPLWCATRGAVAIDDSDPDAPHQAQLWGLGRVAALEHPDWWGGLVDLPASPDTL---DAERLRALLT
GACGEDEAALRPTGAYGRRLVPDPIGGR--APRRTWKPRGTVLITGTADGPAAHVARRLAADGAEHLLMLAPGGGDAPGA------VELKAELDALGTGL
TVADHSPAGQDGTARLVERVAEA-SGRIGTIIHTSASGELAPLMELTPQRLAEERAHLDDTGRRLDELCGMGPEDTVVYFSTVAASWGSKDHGSYAAATA
CLDALAHRDR-ADGRPTVSIAWGLWDLPYGGDTPAHTERSRRQGLSPLEPRPALTALRQVLDHDDPRVIADVEWERFAPLFTL-----------------
-A----RPSRLFDAVPAARQAIE----------AARGSAEDTGADEASALRRELGPL----AEDERIERLLALVRAHVAAVLHYESVEPDRPFKELGFDS
IAAVELRNRLRATTGLSLPTTVVFDYPTPRALAGHLLAEVDPGAAG----
>tr|A0A060ZMF5|A0A060ZMF5_9ACTN Acyl transferase OS=Streptomyces iranensis GN=SIRAN1234 PE=4 SV=1
TWRYRVEWRPVADAA--PAAVGSWLVVHPKGAWTDACVALGADGGQVRRLEL--------------AEDDREGLAELLRSRCAEEPPPTGVLSLLALDDD
APP------LPGVAPGLTGTLTLLQALVDAAVTAPLWCATRGAVSVDDSDPDAPHQAQLWGLGRVAALEHPDRWGGLVDLPTSPDTL---DAERLRALLT
GASGEDEVALRQAGAYVRRLVPDPIGGR--APRRTWRPRGTVLITGTADGPAAQVARHLAADGAEHIVMLCPGGGDAPGA------VELKAELDALGTGL
TVADHAPADREGTARLVGRVAEA-SGRIGTIVHTSASGELAPLMELTPRRLAEERAHLDDTGRHLDELCGMGAGDTVVYFSTVAASWGSKDHGSYAAAAA
CLDALARHDR-ADGRSTVSIAWGLWDLPYGGETASHTERSRRQGLSPLDSRPALTALRQVLDHDDPGVLADVAWERFAPLFTL-----------------
-A----RPSRLFDGVPAARQAIE----------AARGPAADTGTDEASALRRELAAL----PGDERAECLLALVRAHVAAVLHYEAVEPDRPFKELGFDS
IAAVELRNRLRAATGLSLPTTVVFDYPTPRTLAGQLLAEVDPGEAG----
>tr|B5GIC0|B5GIC0_STRSH Non-ribosomal peptide synthetase OS=Streptomyces sp. (strain SPB074) GN=SSBG_04126 PE=4 SV=2
--------------------PRDWLVLADTTGLADAFAALVERGDRCRLVRPGPGYAREETGDVTLAPEDPVHLDRLFAELDGEGAPFREVVHLWNLGLP
GLAESGADIGTATARGAWTLVALARVLRARRDTCRLHVVTRGAQPVAAGDAVEPLGAPAWGVTRVLRQELARHRGKLVDLDPVRATPP-DEAAALLAEFL
A-DDEEEIGLRGNTRATLRLQPAAPRLTG-PLPPRLRPDGTYLVTGAFGALGRLLCRTLVRRGARRLVLLGRTPLPPRAAWRTQAIALVR-EIEALGASV
VLAPVDLTDEAAFTGWLATYRAGDPPPLRGVFHLAGQVRDTLLADIDRAAFDTVHAPKTTGAHLLDKHLRDEPLEHFVLFASVASLLTTAGQTNYAAGNA
FLDALAHRRR-AAGLPALSLDWGPWA-TGMIEELGLEHYLHSRGMSSLSPEAGMSVLERVLGQDLAQLVVVVDWRTFLA------------------WYD
T--P----PALVQDLAA----SA-GD---------------RAAEDEGDLL---AAFRA-AGPEERRALVAERFTRLVATVLRAEEIDPAGGLGAHGLDS
LLAMELRARSQAELGVAPPVVALLSDTPVAELAARLHEELTE--------
>tr|B3PDZ5|B3PDZ5_CELJU MxaD OS=Cellvibrio japonicus (strain Ueda107) GN=mxaD PE=4 SV=1
DLLYEFRWHEAELERT-AVQEGHVLVVADCSGLGHHIREQLNAGSQVVLWDA--------------QSRNLEDWENLLKES---ATTCKSIVYLPSLDMD
FSDESVDHIAAVVKNGCDGPLPFIQAMLRISRNISLFLVTQGGQSTQHQDINTLSQSTLWGLGRVLSSEHPEFSVVMVDLDNRDC---ADTIDRLSQEIL
YGGQEQEIAIRNGARLVNRLGRISNTELPGKVTGIVRPDATYLVTGGLGGLGLAIMDWLVDEGAKSIVLTGRNEPNTY---AQQAIARVQ----SQGIIV
KVARADVTSESDIQQLVEYINAE-MKPLRGVIHSAGVLDDGVIAQQTPEKFARVLASKVNGSWNLHRATRHCPLDIFVCFSSIAAVVGWPGQSNYAVANS
FMDALCRYRQ-QQGLPALSINWGPWAEVGMASKLDVIDRMESSGMKALNPKAAVLAMQELLAYGVEQAIFDMNWRAV---------------------FN
NS------ASLKS--KTLLSGFL----------------EKNDQSDCVDFASLY----RSTPAPLRAALVQEKSCGILADILGFDQIEVTTNLFEYGLNS
LMAMDCKNRLQNLFAVKLPATLLLKHPTIAGFSE----------------
>tr|A0A0C5VY19|A0A0C5VY19_9GAMM Polyketide synthase modules-related protein OS=Gynuella sunshinyii YC6258 GN=YC6258_03213 PE=4 SV=1
NWLTEVHWINKDIPEEATASNGTVLVVGDRRPLIECVSRLRDMRQPFCMVDHDPGFVFEKQSQALFDTASREDWQAFFGALKDSLPACDGILDLRQLSVP
ELDCSPETLASQNSYATYPLIAMAQALLASQIQARLLIVTARGQAVLPDEGPNPLAAAAWGVGRVLWQELITNRGSLLDVDWQQGDGATEAVEHILTELR
ADVYEGEVAWRQNQRYACRLRAAENLGR--PLPLQLRPDACYLVTGAFGALGQLLCHTLVDRGARRLILMGRTALPERSEWSGKQITFVR-SLEAKGVDV
ITAAVDVSYEESLSAWLQDFRQWQLPPIRGVFHLAGQVRDTLLADMTPESYNAAYDPKVVGSYLLHQYLHDQPLDYFVMFASVASLLTTAGQTNYAAGNA
FLDALAHYRR-SQGLPGLALDWGPWA-TGMIEDLGLIHYRNSRGMNSTAPEAGMDIVERVLGQDVPQLMINVDWPLFN----------------------
---------AWYQEMP------------PIIAELASSQQQAAGDEDHGSFLERYRW----ADESDRQTLLEEHFVFVVSDVLRISGVSMASNLNDLGLDS
LLAIELRARIQRDIKVSLPVVTLLSGTPVSDLIAQVEG------------
>tr|Q21E99|Q21E99_SACD2 Amino acid adenylation OS=Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) GN=Sde_3725 PE=4 SV=1
SWLTEVNWIEAPVKA--TTTEGCTLVFGDAQPLAAVVKTFKLRNQPYCVVSAGEQFNFQELNKATVQANNQADLETLISSIE--NTKCEAILYLWQLDAP
QLECELEQLDASHSYNTYPLITLAKALGAIKNNARLIVATRSAQAVSTTDIPQPLPAAAWGAGRVLWQELVDNRGKLVDLDQHHADSDAHIADQLLHE--
--QDEAEVAWRNNQRFCARLQPATNLSR--PLPLRLRTDGCYLVTGALGALGRLVCQTLVKRGARRIILMGRTAIPPRKEWHKSHIEFIQ-QLEANGAEA
ILAPVDVTNEHSISSWLADFKEQGRPPIRGVFHLAGQVRDTLIAEMQPETYNAAYNPKVLGSYLLHRHLAAEPLDHFVMFASVASLLTTAGQTNYAAGNA
FLDVLAHHRR-AQGLPGLAIDWGPWA-TGMIEELGLIHYRNSRGMSSLSPEAGMDVLERVMGQNHAQLMVNIDWPLFT----------------------
---------AWYPTLP------------PLIVDLAAQQKEAQGETDQGAFIDRFKQ----ADESQRFALLSEHFTHVVSDVLRIELVTAESSLNDLGLDS
LLAIELRARIQRDMKVALPVVTLLSGTVVNELINKINT------------
>tr|A0A060ZBC6|A0A060ZBC6_9ACTN Beta-ketoacyl synthase OS=Streptomyces iranensis GN=SIRAN154 PE=4 SV=1
EWLYRAVWQPAAEIQS-VDGGGTWLAVVPGGGAGDELLALAG---------LGMTFRRVA----------VEDIEQLGD-----EPAPRGVLSLLALDEE
SHPE-----YPAVGRGLLSTARLVGALEEAGIAAPLWCVTSGGVGTSGDRVRNVAQSQVWGLGRVAALEHPQRWGGLIDLPEHADDA---AVTLLAQVLT
GDGSEDQVAIRRSGVLVRRLARATPT------PGGWNPRGTVLVTGGTGALGSHVARWLAAEGAERVVLVSRQGEAAPG------ASELTSQLTGLGAEV
SVVACDVTDREALGRLVGGL-----PELTAVVHTAGVGAYRSLAESGDRDLAEVMAAKVAGAAHLDDVLDDRDLDAFVVFSSVAGFWGSGGQGAYAAANA
YLDAVVERRR-ARGRSGTSVAWGPWAGDGLAARPGMAQQLGRQGLTLMDPGVALAAMRAVAANDEPVTVADVDWGRFAPAFAA-----------------
-AA----PRKLIGDLPE-VRRAL------------------EG--D-AAL---------SPTPSTSAGDLLDLVSRQAAAVLGYATVDPGKAFRDLGFDS
LTAVELRTRLAATTGLRLPATVVFDHPTAAALAGHLRAEL----------
>tr|G8YZM3|G8YZM3_STIAU Trans-AT type I polyketide synthase OS=Stigmatella aurantiaca GN=rizC PE=4 SV=1
---------------------------------------------VLVLVEPGETYARLDEHHYRINPAQLGDYQRLRSELANRGIDPRLLVHGRFAPSS
RH---VGSHPGRVAEGFSSLLLIVQGFGLEGLPRRLVHIFE---STPGE--TPPAHAACAGLLRTIERESPKWRCANVEIQGSLIESGPRIAQLISAEAM
GVDNDVEVRYSGNRRLVRRFKPAAVTGSA--DLLAQMSGKVCLITGGAGGIGAHLAQFLTRAQGARAVLCGRSPAASID----RRVASL------LGERV
VYMQADVTKVEDVRRVVAKTRER-FGQIDGVLHAAGVLRDALILNKTLDAAHEVLATKIDGALLLDEATREDRLSFFALFSSLSAVTGSLGQSDYAFANR
FLDAFAEHRESLRSGRTLSVNWPLWQEGGMRIDERVEEMRERFGLEPIMSEQGGTALLESLQGRAAQLILGGDAARFQSAFAV-----------------
--------AGLFDVG--------TSKEPSQVAPPVPSPRT---PVDRG----------------ASFERMTAVVRNLVAQELGIERIGLGESFQRYGMDS
VLAVSIAHELDKQFG-EIPKTLLFEHHNLGALADWIATHRS---------
>tr|L8P1R0|L8P1R0_STRVR Putative Modular polyketide synthase OS=Streptomyces viridochromogenes Tue57 GN=STVIR_8608 PE=4 SV=1
--LFETRWQPRPVADE-PPGRGGWLILADDSGVAAGLVERLGTSVPCVVARRGVEFAAEGHGRYVLDPADPQHLARLLDEAFP-SEMPERVVQLSALDAP
AIED-AHTAGAAARLCCLSTLHLVRALADRGPAPRLFVVVRGSQPAGDSRVAHPQQALAWGFGLALAQEHPELRTTLVDLPPTDG------LDALCTQLR
HADDERLVALRGAGRLVPRLARTRPDDGG---HGAVGPDGVYLITGGLGGLGRVVAERLVRRGARRLALLSRSTPTAEA---ADWARGL----AERGVAV
HLARADVADRDGLSAALDAVRHE-LGPVTAVIHAAGVLDDATLANLTDERVLRVLAPKVLGTALLTELIPEAR--DLILFASAAGLLGSAGQSPYSAANA
FLDAWAHHLS-HTDRRALSLDWGAWSGVGMVSGSGARAETARSGLVAFSRQDGGELFDRVLTTARRQLPLALDWEMLALD----P---------------
-D--AARTRPLLADL-------V------------TAP---TGTPGTDDLVKSVF---AAPTDAERALRLEAYVRSRVGEVSGAVQVSATTALKELGLDS
LMLVRLRNAFARELGVELPAATVFSAADIRGLARALSTAL----------
>tr|K1V729|K1V729_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces sp. SM8 GN=SM8_04255 PE=4 SV=1
--LSRIEWRPAAAPPAPPDTTGTWVVLRHDDRLADETGRLLRTGARVVDAYLEAPAGREGHDHHVLADTGEAAFRGLWE---AVGEEVAGVVHLGNSGPV
R------AEDTELATGPYGCAAALKTLGERQRRARFLVVTHAAQPVADGDRPVPARAALWGLMRTAAVEYPGLRPRLLDLDEESE-------PALAAELG
DG--PPETGYRHGVRHEPVRVPTRPGAT---GTPPVRRGGHYLILGGHGGLGLALAERLAHEGAAVVALASRSGGASTGH---PPSQQI----EGTACSL
RSYAVDVTAPGALTDLVGRIRAD-IGELHGVVHAAGTLKDGLLRSATAEDLAAVMRPKVDGVRELAAAVAGSELDFAVLFASVSGAFGNLGQGGYAAANA
YLDGFAHAH----GAPWTSVDWGLWGETGMGTAV--AAQLRRRGVRPLGTTEALDALLAVLGDPPRQVVIAHDASDT-----------------------
------------------LADEEPPPAPVR---------APAGK---------------APTPHAQRARVEDALARFLTDRLGLASFDRATPLADHGMSS
IMSVELAEELSRRWDVHLPATLFLEYGGLTELAEALTERY----------
>tr|Q8GBX7|Q8GBX7_SORCE Polyketide synthase (Fragment) OS=Sorangium cellulosum GN=spiG PE=4 SV=1
AWRYRVAWRALTAPPK-GDIAGTWLVVAPEVALADGVARALARGARGVLVP-----------------VDAEDAAPLAGRLRAGGQAIRGVISFAALDER
PAP-----LEPSVPLGLAVSLGLVQALGDAAIDAPLWLVTRGAVAVGASRVTRPLQAMTWGLGRVVALEHPERWGGLVDLGEESAPDANNVHDRLANLVA
RRDDEDQLALRAAGTYVRRLVRAPHDGA---RPPAFAPRGAALVTGGTGALGAHVARWLARIGAEHIVLASRRGAAAPGA--AALAEE----LSALGARV
TLAACDVADREAVAALVRDVEA-GGATVRAVFHAGGAMHEAPVAAMRVEELADAIAAKARGAQHLHDVFAQRPLDAFVLFSSGAGVWGGGRQGAYAAANA
FLDALAEARR-ADGLAATSIAWGAWAGGGMLATD-AERRLKHRGVAPMDPELAVAALAHALDHAETCLVADVDWARFAPSF------------------A
SARP----RPLLDELAEA-RSAL--------DALREPPRTAAGPEPASTLRTTLAAL----PEGERHRHLLALVRTETAAVLGHSRVEPNRGFFDLGLDS
LMSVELRRRVQRATGIKLPATLAFDHPTPSALASKVLAA-----------
>tr|D9T6X0|D9T6X0_MICAI Acyl transferase OS=Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442) GN=Micau_2470
SWRYQDTWKPLTGVAN-RGMDGTWVVVLPTGDIIEPWQAFAAAGATLVPVAVSTP------------DVDRDQFGKLLRELAAAPAEVTGVVSLLAFDEL
AH-----PLHPSVPGGFAATVALFQALGDIGLRAPMWSVTSGAASVGMDLLRSPVQSLVWGFGRVAALEHPQRWGGLVDLPEAVED---RCADLLVAALT
TAGDEDQIAVRPTGLLARRLTRVPLGDSQ--PANPWQPYGTALVTGGTGALGGHAARWLARSGVENIVVVSRRGMAAPG--AQQLVDDLT----ALGAQA
VVAECDASDREALAELIDQIPAEY--PLTVVVHASAVLDDAMINDIRPEQIERVLQAKVDVAYNLHELTLDHELSAFVMFSSFAGSVASSGVGNYAPSNA
FLDALAQHRR-GLGLTATSIAWGAWAGGGMADGP-LGDLLHRHGVPEMTPEAAITALHQAVDHGEAFLIADIAWERFSVAFTAT----------------
--RP----GPLISDLPDV-R-RLA--------AAEAVASVEVGD-GPESLRDRLAGLP----ATERFAVLLGLVRSQVAAVLNYESVDEHRAFRELGFDS
VTAVELRNRLGSATAVALPVTLVFDYPTPTTLAEYLYAEVAHDDVVTP--
>tr|A0A0D0X4V4|A0A0D0X4V4_9ACTN Acyl transferase OS=Micromonospora carbonacea GN=TK50_11440 PE=4 SV=1
SWRYQDTWKPLTGIAN-RGMSGTWVVVLPTGDIVEPWQAVTAAGATVVAVPVSTT------------DADRDLLGKLLRELAASGADVTGVVSLLAFDEL
VH-----PLHPSVPGGFAATVALFQALGDIGLRAPMWAVTSGAASVGRDLLRSPTQALVWGFGRVAALEHPQRWGGLVDLPEAVDE---RCAGLLVAALT
AAGDEDQIAVRPGGLLARRLTRVPLGDSQ--PANPWEPYGTALVTGGTGALGGHAARWLARSGVQNIVVASRRGMNAPG--AQQLVDDLT----ALGAQA
SVVECDAADRDALAALIESIPAEY--PLTTVVHASAVLDDAMINDIRLDQIERVLQAKVDVAYHLHELTLDLDLSAFVMFSSFAGSVASSGVGNYAPSNA
FLDALAQHRR-GLGLPATSIAWGAWAGGGMADGP-LGELLHRHGVPEMAPDAAIAALHQAVDHGEAFLIADIAWERFSVAFTAT----------------
--RP----GPLISDLPDV-R-RLQ--------ATERIATVETGD-GPDSLQERLAGLP----AADRLAVLLGLVRGQVAAVLNYESVDEHRAFRELGFDS
VTAVELRNRLGSATGVALPVTLVFDYPTPTTLAEYLFAEVAHDDVVTP--
>tr|H0KB74|H0KB74_9PSEU Beta-ketoacyl synthase (Fragment) OS=Saccharomonospora azurea SZMC 14600 GN=SZMC14600_21943 PE=4 SV=1
SWQYRISWRPVRLPEP--RPQGDWLIVVPSGPVDDDLLSVF--GERATVVES-------------------ADRQTLATRLREVDEAPKAVVSLL-----
--------------TDVVDLLALVQAMGDARIEARVWAVTRGAVSTPGERVEDPAQAQLWGFGRVAALEQPDRWGGLIDLPVDADA---GTCARMLGVL-
-EADEDQVAVRRSGVFARRLVRVTEPV-----ESPWQPRGTVLITGGTGALGGHVARWAAANGAEHLVLVSRRGPAAEG------AEALTAELRELGAEV
TVVACDLTDREAVAELVRD------TPPSAVVHAAGVLDDGVIEGLTPDRVRGVLRAKVDGATLLHESTGD--LDAFVVFSAFAGAIGSAGQASYAAANA
HLDALIEQRR-ADGLPGTAIAWGPWAGEGMAAGVA--DDLAALGLPALDPGSAVQALADAVGSTHPAVVADVDWPRFGPLLG------------------
--------GRLLAELPDAA---V--AEPARR---EPAPDSLAGAV---------AGLS----RQQQEARVLEVVRAEAATVLGYESVTSDRAFRELGFDS
LTAVELRNALGTVTGLSLPSSLVFDYPTPAALAAWLCDEL----------
>tr|A0A0M8TQ14|A0A0M8TQ14_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. WM4235 GN=ADK55_08560 PE=4 SV=1
---SRIVWRSAPADAAREPVTGTWVVLHDADGLGARAARLRADGARVVEVGIGPSGPRAGDRDLMLSQPDEEAFRRLWDEV---GDPIAGVVHLWNAGEV
SDGA--QGEETELRLGLYGCLAALRTLGERQRKGRFLVVTRDGQAVADGDRPVPARAALWGFLRTAAIEYSGLRPRLVDIDRSSD----DALQALLAELG
DSDGPTETGYRQGVRRVPVRVRDRSAAAPRSRPGPVRQGGHYLILGGHGGLGLEVADRFARDGAGVVALVSRSGAAAVDR---QRTAAI----RAHGCEI
VSYSADVTTPGALAAVVQRARAE-YGVLHGVVHAAGTLKDGLIRSATAEDIAAVMRPKVDGVRELATAVAGQDLDFAVLFASVSGTFGNLGQAGYAAANA
YLDAFAQA----HGSPWLSIDWGLWGEVGMGTAV--AEQLRRRGVRPLGTAEGLDALIAVLGSRERQVVVAPDAGD----EVIE----------------
---------PEAAEAEAE------VEAPSVVRARTGVPNTAGGTAGA------------GGSGVGAGEHVADGLERFLAERLGVASFDRDTPLSDYGMSS
IMSVELSEELSRRWGIHLPATLFLEYGEFAELVQALTDRYG---------
>tr|F0SIS4|F0SIS4_RUBBR 6-methylsalicylic acid synthase., 6-deoxyerythronolide-B synthase OS=Rubinisphaera brasiliensis (strain ATCC 49424 / DSM 5305 / JCM 21570 / NBRC 103401 / IFAM 1448) GN=Plabr_3151 PE=4 SV=1
-LLYDIRWQDYRLPDN-SLDPKTWLVVAASEQAADALGMLLERGHRAVHVDAGESGELEQEGRFLIDGHDASQWTQLLTELKAADISLDGI--AWHIDSK
SDQSP----LAVADQHCMSVITAINAFTKAGIECGFQIVTCDGVSTGASLPVIPAHSQFWGFGRSLAAEQPTFQIRLVDQSSAVDSDSSPKAAFLADYVL
NSTPENQIAIRNGQYFIPRLQRVSSDEAE-QVNFPISSEGACLITGGLGMLGQETARWLAAQGAGHLVLVSRRPPNEA---TVATIEEIR----SAGTEI
TVAQADSSDREAMSALLKRFGT-DLPPLKGVVHAAGVLQDGLIADQTSERFEKVLSPKVIGAQLLHELTEPMELDFFILYSSAASMLGSPGQTNYSTANG
YLDGLAQSRI-QAGLPALSLNWGPWT-IGMAADENIARRMELQGIVPLDVS-AHQVLPHALSQGISQLVLDVDWRRLNAASGG------MSP--------
---------PLLADVM-----------PAR--------KRSAGA--SSEFIKKLRAL----PVHERRDSLRDSIQLEFQAILGSDELATDRPVIEFGLDS
LMAVEFSSRLQSLVGEEIAPTMLFDYPTIDAITGYVLEQLGDDETPSP--
>tr|A0A014KXC5|A0A014KXC5_9ACTN Polyketide synthase (Fragment) OS=Streptomyces sp. PRh5 GN=Z951_46005 PE=4 SV=1
GWRYRVSWKPVPDAAEG-SLSGTWLVVVPASRAGDELVGLERHGAGVVSLVADERDL--G-------------AGVLAARLRAEVPELGGVLSLLALEEE
PCPGY-----PGLSGGYALSLVLAQAMVEVDVPARLWCGTRGAVSVGRDRLAGAVQSQVWGLGRVVGLEHSAVWGGLVDVPESLDE---RGVARLAGVLS
AGDGEDQVAVRGSGVFARRLVRADAGE---GAERPWRARGTALVTGGTGALGGRVARWLARSGAEHLVLTSRRGLDAPGA------TELRDELEALGARV
TVVACDVTDREALAGVLASVPE--EFPLSAVFHAAGVEQAAELRGMSLSDAAAVVSGKAAGATCLDELLGDRELDAFVVFSSIAGVWGSGGQAAYGAANA
YLDALVEDRR-ARGLAGTSVAWGPWAEGGMAAAEGVESELARRGLLALDPALALAALRGAIAGDDGVTVADMDWERFAPSFTLGR---------------
-------PSPLIGDLPEV-AKAL-----------EAV-SASGGAHTSAGLRERLTGLT----EAETDRVLLDLVRGHVAAVLGFEVVEPDRAFKELGFDS
LTAVEFRNRLMAETGLVLPATLVFDYPSAAVLADHLRAEVL---------
>tr|D1GLV7|D1GLV7_9ACTN Polyketide synthase type I OS=Streptomyces lydicus GN=slgA3 PE=4 SV=1
DWFHRLAWHPLTDRATAPAPTGTWLVVAPARRPDDALVALEEGGAEVVLVEPARAAA--G-------------AASLADRLHAGGRQIEGVLSLLGLAEG
EGPGH-----PGTAPGPALTLELLRALDAGDVPAPVWVATRGAVSVGRDRPADPAQAQTWGLGRAAAREAADRWGGLVDLPVDLDV---RARARLRAVLA
GAIPENEVALRPSGAYARRLVPAPPAT---GRAPAWTTRGTALLTDVTTPEGPHLARWLARAGAEHLVLLAPPGTDTPE--------QLADELAELTAEV
TVARCDTRDRAALAALLDSLTAS-GRPVRTVVHTTGTPHPAPPSGTPRAVLADTLPARVAGAEHLAELLDHDALDAFVVCSSAAGTWGAEGQAAAAAADA
HLSAWAARRR-ESGLPVTVVAWGPWAGNDPTDG-----AATGDGLTPLPPAAAVRALHRILDGGGTRIVADVDWERYVAGCPAGR---------------
-------ISPLFRELPPV-QAAL-----------AAH-AAPPGDWTPEELRRRLAGLP----ADQRPALLLELVRARSATVLGHRSVGADDDFLDIGFAS
MTAVELRNQLVADTGVELPPTLIYDCPTPAALATYLLEEVQ---------
>tr|D7C3U7|D7C3U7_STRBB Modular polyketide synthase OS=Streptomyces bingchenggensis (strain BCW-1) GN=pks7-2 PE=4 SV=1
--LFETRWLPRSAAREL-PTRGSWLILSDESGVGAALSGLLGPAPH-VVARRGDSFAAEAPGRYRLDPLNPEHLARLLEEAFPE-GPPERVVQLSALDAP
AID-SAEAATRVARLCCLTTLHLVRALAERGRAPRLFLVVRGAQAAVSTEVTHPQQALGWGFGLAVAQEYPELAATLIDLPTDGG------LDALWTQLR
HADDERLVALRGTGRLVPRLVRTRPDDA---GRGDIGPDGTYLITGGLGGLGRVVAECLVRRGARRLALLSRGAPAPE---AARWLEAL----RGRGVTV
CHARADVADRQGLTAALDGLRRE-LGPVTSIVHTAGVLDDATLPNLTDERVERVLAPKVLGTALLTELVPE--AERLVLFSSAAGLLGSAGQSAYCAANA
FLDAWAHHLA-RADRSALSLDWGAWTGVGLVAESDTAASVGRSGLIGFSPQEGGELFERLLPTARRQLPLALDWAALASDPDV-----------------
-----ARSRPLLSDLATA---------------LDAAPAAAAGA---DGLVERV---LTATTARERTDRLEAYVRARVGEVAGVMDAAPTTALKELGLDS
LMIVRLRNAFTRDLGVELPTSAVFSAADIRGLARDLGSA-----------
>tr|A0A0M5JD74|A0A0M5JD74_BURPE Peptide synthase OS=Burkholderia pseudomallei GN=AMS56_27630 PE=4 SV=1
QWCRTVSWRDAPAARA--LPPERWLVFGDEWF------ALA--PAGSVLVREDDAFRAHGDNGYGVRPGEKADCDRLIARLAEQGGVPAHVVYGWAQTDV
-------------DRAFAGLAALLQALGAHPADFRVSLVTKGARSART--LDACAAAAPAGLLKAVRWEYPRIVCRHIDIDDASDA----TIDALRAELS
SEPLPSSIALAGARREAPGFAALPAVA----RDDVLRDGGAYLITGGASGIGLELAAHIASRRDVRLALLSRSPHDEN----AARFAALD----EAAASV
LRLTADVAHAAQLADALRTVRAR-FGRIDGVIHAAGVEASGLLETGTPDAWRRVMAAKVHGARHLFDQLAGDPPDFIVLCSSLAAVVGGLGQADYAAANG
YMDALAQHWR-QRGVAAIAIDWDTWSDTGMAFDHAARTRNDRPGLPGLANREGRALFDLALAHDASRIVISKRG------------------------FE
QD-------R--------------RDAPTR---------------AR---------------RAAAPGDAQAALVALWQELLGVEQVGVDDDFFDLGGHS
LLATQLISRVRDQYARSPTLGEFLEEPTIARILRAIDHT-----------
>tr|D9W5P1|D9W5P1_9ACTN Modular polyketide synthase OS=Streptomyces sp. C GN=SSNG_07471 PE=4 SV=1
SWRYKAAWTPLTAAPAPTAPAGTWLIVTPPQGVAGTVAALAAHGVETVVLET--------------DPAGA-DRGALTERLGEALPGLGGVLSLLGLDEA
--------------AGATGTHVLVQALADAGITARHWAATRGAVAAGADAPAVPAQARVWGLGRVVALEQPAGWGGLVDLPATLDQ---RALDRLAKVLA
GYGDEDQVAVRTSGVLGRRLVRAPLGDRE--PLRRWEPSGTVLVTGGTGGVGAQVARRLAATGAAHLVLTSRRGAEAPGA------AELAAGIRALGTDV
TLAACDVSDRDQLKAVLDAIPAD--RPLTAVVHAVGVPQYTLGTETTAAEFEQLSAAKVAGAEHLDALLDGTDLDAFVLFSSNSGVWGAARHTAYASANA
YLDALAERRR-ARGLTATSVAWGAWGGGGMMELEGAQEYMRRRGVLEMDPQAALNAMVQAVEHDEAFVVADVDWARFAPGFTS-----------------
-ERP----SPLLTDLVPQ-------AAPTA-------PQPVD--ESSSALVRD---LRA-ATPGERTTLLTDLVRAQAAAVLGHEAVEAGRAFRELGFDS
LTVVELRNRLTAATGLTLPATLVYDHPNPAALARFLGAEL----------
>tr|H1ZZU1|H1ZZU1_9ACTN Type I modular polyketide synthase OS=Streptomyces albus subsp. albus GN=salAIX PE=4 SV=1
SWRYGITWKPLTAPAA--RLEGSWLLVTGQDGRAALLAALAAHGAETVVLET--------------DPLAL-GRTALSGQLAEALPELRGILSLVGTGAA
--------------NGAASTLLLVQALADASVQLPLWCATRGAVSVGGDAPAEPDQAALWGLGRAVALEQPAVWGGLIDLPETLDE---RALGRVARVLA
GIEEEDQVAIRATGTFGRRLARRPLHDAV--PERVWQPRGTVLVTGGTGGVGAHLARWLADNGAAHLVLTGRRGADAPGA------AELAAGIRESGTEV
TLAACDAADREALAAVLAAVPES--APLTAVVHAAGLPQSTLATDTTYEDFVQLTAGKVEGARHLDALLGDRELDAFVLFSSSSGVWGAGRHTAYGAANA
WLDALAEQRR-TRGLTATSVAWGGWSG-GMMALEGAGEYMRRRGVGEMAPERALAALRQAVEHDETFVVADVDWEKFAPGFTS-----------------
-ERP----SALLTGLPEV-RRALAPAAVAA-------PRQAE--ESASDLVRS---LRA-GTPAEREAQLLGLVRTEAASVLGHEDVEPGRAFREIGFDS
LTVVELRNRLSAATGLKLPTTLVFDHPSPLALARFLGGEL----------
>tr|R1FV99|R1FV99_9PSEU Type I polyketide synthase (Fragment) OS=Amycolatopsis vancoresmycina DSM 44592 GN=H480_37415 PE=4 SV=1
SWRYRVEWKPVATPSA-PELAGRWLVVVPGAGVPAALA---AHGAPVVTS----EFT------------GAEGYA--------------GVVSLLALDET
--------------AGAVANLALAKAMAG--SETPLWLLTRGAVT-----GVSPAQAMTWGLGRVIGLELPGIWGGLVDLPAEPDAT---TAPLLAAALS
GVDDEDQLAIGPSGLLVRRLVRAPFTPP----AQRWKPRGTVLITGGTGALGGHVARRLAADGAGHLVLTSRRGPDAPGA------ADLEAELSTMGTRV
TIAACDVADRDALAALLTGLD----EPVRAVVHAAGLPQATAVLDTTPAEFAAVIEGKVAGARNLDELLGD-DLDAFVLFSSNAGVWGSGGQGAYAAGNA
YLDALAEQRR-ARGAAATSVAWGFWGGGGMAGDVELEDQLRRRGLREMAPEAAVEALCQALDAREVFAVADVDWARFTPGFTLSR---------------
-------RRPLIEDIPE-VRAL-----------LSEEPET-----ERPALARRIAGLG----EAEARRLLLDLVRGQAASVLGHDAVPAARAFRELGFDS
LTAVEVRNRINAATGLTLPATLVFDHPNPAALAAELHRL-----------
>tr|V4JIJ7|V4JIJ7_9GAMM Uncharacterized protein OS=uncultured Thiohalocapsa sp. PB-PSB1 GN=N838_08270 PE=4 SV=1
SWLYRPQWALKEQEDEEPQLAKAYLIFADLGGQAQRLAELRRRGCAVSLAFPGSSYSAGDLGEFILEPNNIEQLRTCLQAFATRYPEDSGIIHCIGLDGP
PSLDQMKELESLKESHLHSLIFIARVICEADLRCKLWVVTGSGQVVTEGDRINVLAASITGISRVLAQELCDNWGRQIDLANQ----GEDLIPAIVSELG
SPAEEQEVGHRDGRRYVSRLVPAEGLRPP--FPVRMKPNACYLVAGGFGAIGRLVCRWLIHKGARRILLITRTTFPSRDSWKSERIAFVN-ELESMGAEI
LLADVDVTCESELRHYFKDYEQQMYPPIRGVFFCSGVVKDALVSSIEREDFDPVYETKTVGATVLHQCLADTPLDHFVLFSSIAGQVATAGQVNYAAANT
YLDALAQYRC-AIGLPALSINWGPWA-IGMIKELGLADYKNQRGMPPILPEAGIKVLERILDLPDPQLVCDAHWNKVR-------------------DWY
PKR-----PALFKD--------L----------------GDEGEVDEQAD-DFLSRYV-YSPSDQRKNLVELEFKKQIAQILRTGKIAGTDVIVALGIDS
IMGVELNNRMLAHFGTRLSVVKLLGNLSIRALAEELEQKI----------
>tr|J1ZLY7|J1ZLY7_9ACTN Type I polyketide synthase (Fragment) OS=Streptomyces auratus AGR0001 GN=SU9_33888 PE=4 SV=1
GWRYRIVWRPQPEPEQA-KLAGPWLVVVPADYLDNDLVRIGDNGATVLLVLEDSTTDR------------QGVADQLRNSLV--TGAPSGILSFLALDER
PLTEF-----PEVTVGLVQSVALMQALLDADVEAPLWLLTTESAATADDAVRNPLQAAVWGLARVFALEHPKQWGGLVDLPAALDDRG---AALLSGVLA
AGGDEDQLALRGSALLTRRLTRAPLDGGE--PAAPWRTSGAALVTGGTGGLGAHTARLLARSGAEHLVLTSRRGPDAPGA------AELRDELAALGARV
TIAACDVTDADALAELVAQVES-DGPAIRSVVHTAGVGLLVPLADTTLQEFAEGARAKLLGARNLDALFDRDGLDAFVLYSSVAGTWGSGDHGAYAASNS
YVDALAAHRR-ARGLTGTSIAWGIWSPGGMAVDV-VQEQLRWRGIPFMPAHLAVMGLQQALDHDETFLVADIDWERFVPV------------------FT
AAH----RRPLLHEVPEVLRA------------LEADEDTDAAESTSESLRTPLAGLA----PAERERQLSDLVRKQVAAVLGYSEVEVGRAFRELGFDS
LTAVELRNRLNTATGLKLPATVVFDHPTVKALAGHLETTL----------
>tr|A0A059TYE0|A0A059TYE0_9BACT PKS/NRPS hybrid OS=uncultured bacterium 12-5D GN=5d6 PE=4 SV=1
-------------------KPSTYLVFADGGGVAENLTEILGAGGNVVRVKAGEAFVIHGPSEYAVAPDSKDDIKRLFEELAKSGTHPRFILHCWSLDHA
DSDDSLESLQNDQRTGVLSGLALAQAVDACGRAPHVYFITRGAQGVLEGGPSRLASAPLTGLVRVANNEQPNTKWTLIDLDPKRPT---TEMEDLGNELF
LGDGELEVAHRDGRRYANRLHNVKADPRPTEDENLFRPDASYLITGGAGGFGLELAKWMARQGARNLVLMSRSGPRD--DDAKEDFEAM----RAAGINV
VDARADVTSREDVQKVLDQIQAE-LPPLRGVIHGAMVLDDEFLIELDNDRFNKVLNPKMLGAWNLHTLTLGLPLEHFISFSSFSAVMGAVKQSNYNAGNY
FLDSLAAYRH-SHGLPALTFNWGALSGAGFVERNKTAQYLEMIGLKPFNMDETLRVFRRMLPLDPVEVASRVDWNSIGRLPMIA----------------
-------QANMFAPV---ARKHLEG---------------EGGSSVRPRI---LS-----AAPEEQLRLVEDFIAEQVAGVFGTSKIDRHTPLTNLGLDS
LMAIELMNRIEGELGITLPMGAVLNGPNLKELAVPVLNTL----------
>tr|I4GFX0|I4GFX0_MICAE Peptide synthetase and polyketide synthase OS=Microcystis aeruginosa PCC 7941 GN=mcyG PE=4 SV=1
-------------------TAKNWLIFTDVEPQQNTFQQLLKKCDSCRIIYQGEKNTQISSSESCLNANQLQQLEEWFA----SNPSPDRIIYLLNSDGK
DQP------ESILLNRCNYLLNLLKAIQKIPNPPQLFLVTQGAQPFELEQPSLGFQSPLWAMGRVIALENPQLWGGMLDLDPDVDIN--QNITALLLGLT
HAHDEDHLVFRKGQGYVARLLPLKSLET---KTVKIQPEATYLITGGIGHLGLELAEHLVNLGAKHLILTTRRSLPVRFDSAAQISEKIRK-LEEKGASI
AVISADVGNFEAMQAIFTQIEKTAY-PLRGIFHLAGISGQAQLKDCTLQDLEAVFQAKVKGSWNLHQLSLGSQLDYFVLFSSAGAIWGAKEQGLYDTVSH
WLDALAHFRH-LQGLPATTLNWALLAGHGIVSQ-DYEDWLKQIGIREIAPDMALRVMDAIMASNQTQVIADVDWVRFKNIYE----------------FK
GE------KPLLK--------NLGLS---------EVAI--KSVQESDSVLHLLEE----MPFGERREYLLEYVSKQVRIILGIKSPDTEQGLIEMGIDS
LSSIELKNRLEKRLEVLLPTSLVFDFPNIRRLVDYLLDRI----------
>tr|Q8G985|Q8G985_PLAAG Peptide synthetase OS=Planktothrix agardhii GN=mcyG PE=4 SV=1
-------------------ISENWLIFTDSHPEKDHLQQLSKNYGSCTIIYQGQNKIKLSQFEYSLNAHQPEQIKAWFA----ENPSPHRIIYLLNDNHQ
DQP------ESILLNRCHYLLNLLQAIQKIPNSPKLFVVTQGGQPFELKQPTFVTQSPLWALGRVISLENPELWGGMIDLDPSADIT--QNIADLLLGLT
HSISEDHLLFRNGQAYLGRLVPSTSPPT---KPLTIQAEATYLITGGIGHLGLALAGHLVDLGAKHLILTTRRPFPPSSEISAKIMENLRI-LEQKGVSV
EVCQADVGDFEQIQAIWAKIEKTAY-PLRGVFHLAGVSGQAQLSECTFADLEIVFQAKVRGSWNLHRLSLATKLDYFVLFSSAGAIWGAKAQGLYDAVSN
SMDSLALMRH-LQGLPATTLNWALLAGNGIVSP-DYEDWLKQIGMKEIDLDRAFSVMDAIIESNQTQIVADVDWVRFKNIYE----------------FQ
GD------KPLLK--------KLGQS---------QNII--KSVQDSSSTRRLLED----IAPGERREHLFQYIGKQVGMILGIKQPDPEQGFSEMGIDS
LLSIELKNRLEKGLEVTLPASLVFDFPNIRRLVDYLIQQV----------
>tr|H3SB85|H3SB85_9BACL Polyketide synthase OS=Paenibacillus dendritiformis C454 GN=PDENDC454_03854 PE=4 SV=1
--FHHKRWVVQDEVTVLPPTEETWLVHCDSHGTP-LLARLREEGVRVIEVFLHDGFTQIDQDTYRIGN-NADDFKELFLQLS--DLPIRKIVHVGAYRDD
DPG-SVNDMYQEFEYGFFNVVHLVKGLVKADQPVQLILVACNAYRISGEERLLPHHATVLSLGKVIEQENPNISCRAIDTDRDTD------VGQIIGQLF
ADHQMYLIGLRQGTSYVEEFDEAEIQPE---TANRIVHGGTYIITGGTSGIGIQNAKLFSEQANCNLILLSRKGFPDESLWEKEQIKEFKQ-MKKNGAAL
EFIACDVTNADDVQTMLEAVRTR-YKKINGIVHCAGVIEPSFMLRKEKESYLSVFAPKITGTWNLANLTRNDDLDFMLLHSSNVTDAGEPGQSCYMAANA
FLDAYTDYLN-AQGRHTYTVNWVAWKETGMAHKQGTNV---DTVTKAITNRDAVNALNQLLRSKPQRVVIGQFNEQVDLVPLLKH-----SRNAVAPSFT
AK----IYKEAYRQIGDAAAPILVEPAPLPIVQE-ASQASPSGKEI--K-------L--TGKMEGIYTPVEKQIGKIYCDILGYEEADIYEGFFEMGGDS
ILLTEMHDTIDKLYPNIVKIADLFEFDSIHSLSEYITPRIPHDEA-----
>tr|A0A0A0NWU9|A0A0A0NWU9_9ACTN Uncharacterized protein (Fragment) OS=Streptomyces rapamycinicus NRRL 5491 GN=M271_45210 PE=4 SV=1
TWRYQISWKPLPDMDT-PALSGTWLAVVPEGEWAMAGRALIESGMSVRTVQVT------------CD-ADRRTLAGLLTDVAG-SEDITGVVSFLAADEV
PHP-----AHPALSRGMAHTVELVCSLTTADVGAPLWCVTRAAVTAPADPAPSPAQAAVWGFGRVAGLERSERWGGLIDLPVHCDA---HVLRRFVAVLA
RAAGEDQVAVRPSAALGRRLESAPRTG----PAGAWRPHGTVLITGGTGVLGAHVARWLARSGAEHLVLLSRRGPQAPGA------AVLDDELTALGVRV
TVTACDVTDRAALAGVLASV-----PDLTAVVHLAGTVRFGNAIDADLDEYAGVFDAKVTGALHLDELLDHSSLEAFVLFSSAAAVWGGVGQAGYAAANA
MLDAVAQRRR-VRGLPATSIGWGTWGG-SLAP--EDEERLSRIGLRPMRPEAAVTELRHVVGSAEPCAIADVDWETFGPA------------------FT
TGRP----SPLLGELPQ-LRNTS-----------GSMAM----TGDHAALRRRLAGVS----AADQARTLVDLVREHAAELLGHAAIDPTVPFRQLGFDS
LTAVELRTRLNAATGLRLPATLLFDHPSCRAVGDLLRSEL----------
>tr|W4DCD9|W4DCD9_9BACL Amino acid adenylation protein OS=Paenibacillus sp. FSL R7-277 GN=C173_20406 PE=4 SV=1
--YYQLNWVEAEKAVPPRTWEGAVLVIVGDGCLSDAIMKELRGQRYVVTAQLGREYSKISAMEYLIRN-TAADFSALLAQMKD--MNLTAIVHLASLSEQ
GGMDSENDLTAGLQRGVCSFRNLHLALAEETADLDLYLIAERVNAIHSDPVINPVFAPMFALAKVMKYENFNTQCKCIDIDSETE------AEVIANEIA
SAAMDSNVAYRKGIRYVERLETFQPLDM-ELKPTGIRPKGVYVITGGTGGLGLQVAHYLSVQNQVTLILINRSCFPDKKEWAADKVKSLQQ-VEGRGSQV
RCYQADVSCPEDMISVLDEVRET-YGSIHGVIHSAGIGTGVSIQEQEEEDFLRTLAPKVQGTWLLDRLTQQDKLDFMVLFTSPVTLIGGVGLSGYTCSNS
FLDSFVHYRN-TGGKRTIAMSWAPWEFTVMGERFNPQ----KQLFQVISSERVREAFHDILNHDVQEIIGGLNYQGE-----------------LLPYYK
EFS-----FRLSDSIIERIKGGLEQ--ASSYQ--------------------RVVEVRYKGEKVPP-HGHSESLGQIIGGVLGMEKLDLESNFFELGGDS
IIAMKVIVQINQVFQTALKVTDLLRFPDLHAFTGFIAEQT----------
>tr|R4LYM8|R4LYM8_MYCTX Polyketide synthase OS=Mycobacterium tuberculosis str. Haarlem/NITR202 GN=I917_20485 PE=4 SV=1
DWCHQLAWPIRPAVSADPPSTAAWLVVADNVTLATSWPVRPILGX------TAXRQXXL---------AAXSDPAALLDALR----GVDNVLYAPPVPGE
LL-----D-----IESAYQVFHATRRLXAAISPPKLFIMTRNAQPISEGDRANPGHAVLWGLGRSLALEHPEIWGGIIDLDDSMPA--ELAVRHVLTAAH
GTDGEDQVVYRSGARHVPRLQRRTLPGK----PVTLNADASQLVIGATGNIGPHLIRQLARMGAKTIVAMARKPGA---------LDELTQCLAATGTDL
IAVAADATDPAAMQTLFDRFGTE-LPPLEGIYLAAFAGRPALLSEMTDDDVTTMFRPKLDALALLHRRSLKSPVRHFVLFSSVSGLLGSRWLAHYTATSA
FLDSFAGARR-TMGLPATVVDWGLWKSLADVQKD-ATQISAESGLQPMADEVAIGALPLVMNPDAAVVVVAADWPLLAAAYRT-----------------
-RG----ALRIVD-------DLL-PA-PE------DVG------KGXSEFRTSLRS----CPAEKRRDMLFDHVGALAATVMGMEPLDPSAGFFQLGMDS
LMSVTLQRALSESLGEFLPASVVFDYPTVYSLTDYLATVLP---------
>tr|A0A0F4ESU1|A0A0F4ESU1_9MYCO Polyketide synthase (Fragment) OS=Mycobacterium lepromatosis GN=ppsB PE=4 SV=1
GWIYQLDWPARPLTSETWASNGSWLVVSDAGLSDE-LARLVVLAD------PASRVECL---------ADVSTLDDLHKALR----GVDNVLYAPSVSTE
SVDP--VD-----PESGYRLFHAVRRLAAATSKPRLVVVTRNAQPVAVGERANPAHAVLWGFGRTLALEHPEIWGNIIDLDASMPP--ELAARCILDEVA
GQDREDQVVYRACLRRAPRLQRRTVSAVS---PVSSGQATTQLVIGATGNIGPHLIRQLAAMGATTIVAVSRSSSTR--------LVELDKSLAATGTNL
ISVAADATDPAAMTALFDRFGVD-LPPLEGIYLAAFAGQPVLLSDMTDDDVAAMFRPKLDVASLLHRLSLKQPVKYFVLFSSISGLIGSRWLAHYTATST
FLDILGYARR-LVGLPATVVAWGLWKSLADVQQD-ATQVSAESGLQPMTDDVAIGALPLVMNPEAPVVVAAANWPILAAAYRT-----------------
-RG----VLRMVD-------DLL-PA-PG------EVP------IQESEFRKALRT----CQAERRHDMLFDHVSALAAKAMGMEALDPSAGFFQLGMDS
LMSVTLQRALSDSLGEFLPASVVFDYPTVYSLTDYLATILP---------
>tr|W7YV94|W7YV94_9BACL Malonyl CoA-acyl carrier protein transacylase OS=Paenibacillus pini JCM 16418 GN=JCM16418_317 PE=4 SV=1
---YQLGWVAAPKLESISIESQAVLILKSALGWGKRISGFRDKGYPVIEVQLGSSTAFIHHGQHVDMQGCQEDFDQLFTDLKGR-YHLEHIVYVGANAPL
ET---KGEQGEASTD-EIYLFRAVKALQSDERSLKLSLLTNQAFVVDDKESIHAERAVMTGLGKAIAKENPDWLCKAMDTDDDAD------VEAVLEELL
HVDKEYQIAIRQGQRYALELQPMDPSRL-KDDPLVIREGGIYIITGGLGDIGLEMAKYLASRQNVNLALISRTAFPNREQWPQSRIEEVMA-IEALGSKV
YCYAGDVSDVVAMEQIITAIRDQSNAGICGVIHAAGVPGNQMLNEQQETEFKRVLSPKVEGTMVLDQLLHGEALDFFILCSSLATFFPAPGQGDYIAANT
YLDAYAAMKS-KQGTRTITINWSTWKERGMAVKAGFA---VDTLMRALRTEEAMSQFDLIVNKDVSQVLIGLDFDSRLIRLLPEMPY-RMHDSIIYEELG
TK--------SRANITAQ-AGML-CSTTAAGSSMGTNSRASNGVA-------RVVQLSG--RENGIYSDAERITAQVWAETLGIYDMNVYHNYYEMGGDS
VLGIRIVNTLNKQLQIRLHPGDLLTRLTVEQFGAFLESMI----------
>tr|D0LN43|D0LN43_HALO1 Amino acid adenylation domain protein OS=Haliangium ochraceum (strain DSM 14365 / JCM 11303 / SMP-2) GN=Hoch_0798 PE=4 SV=1
----ANVWVPAAEPDA-PAHASRWLLVGDGDGLRDRLAELRSHGHTLV--AE--------------------------------GEPHDEIVWLEALDAD
RDG------PEAARVACVTLMERVQRLVQEEHTPRLWLVTRGACEAQGC-LVDPAHAAVFGFARSLAAEHAELRPGRIDLDPGLAPV--AQAAELTRALL
AGDDEDETALRGGARFVGRLQRRLPGQAPVPAHSGFSDNATWLISGGLGGLGLSLAEGLVSWGVRAVALLGRSGVRT--QHQRQAIERM----RAAGARV
RVLEADVSQQASLEAALATLH--DLPPLRGVVHVAGVIDDGMIAGQSAERLAAVFAPKVSGAWNLHRATAACELDHFVIYSSGASLLGSPGQSSYAAANG
FVDGLAWARR-SAGLPALSINWGAFSDVGLAAAEARGERLASKGLRNLTPEEGLRLVRSLLATDVVQVALPFDIARWLESL----------PQ-----LA
-------SSSRFAELVS-------SE------DVDA------G-PAVEDLAALLA----SSVSARRVALCEDYVRRQLAQVIGIDQLPLRRPLTEMGLDS
LTGLELRNRLEAGVGKKLSATLAWSYPTIEALAGHLLEQL----------
>tr|A0A0N1GBL0|A0A0N1GBL0_9ACTN FkbH like protein OS=Actinobacteria bacterium OK006 GN=OK006_9711 PE=4 SV=1
-HLYEVVWTAVPEQPDE-APGTEWAVVGDPSEVAGALRGLAAAGTHV---RSGTGGAD-------VNGAG--GVD----VRGT--GGVDVFVRFWPRPAT
DAEPSA----AAQ-ELAAAALAELRALIALEAPARTVWVTRGAVGAVKDTVPGLAQSVLWGLARSARAEHPELGLTLLDLDDSDPAD------ALLTAAT
-HAEEPELASRAGTLLAPRLVRARDRDATGGRPALAPTDGTVLITGGLGAVGRHIARLLAEHGVPRLLLTSRQGPDDPR--AAEVAAELT----GLGAEV
EVAACDIADATAVAGLLGRIGE--ESPLRGVVHCAGVLADGVVAELTPERLAQVLRPKVDGAAHLHRLTVDARLDLFLLVSSAAGVVGNAGQGNYAAANV
YLDQLAHHRR-ALGLPGVSLSFGAWAGEGLAAAHADLDRMARLGHRALTSDQGRELVELALRQGAPHLVAALDLPRLRETATTAA----------T--TG
VGGTA----AVWRS---------------------LLPAPRTGRSGGDGLADRLARLP----EAERAERVLALVREEISRALGLESVRPDQPLRELGMDS
VTAVELRNRIGARIGAKLPATLLFDHPTAARLAAHLLSTA----------
>tr|A0A0M2JL38|A0A0M2JL38_9ACTN Polyketide synthase OS=Streptomyces mangrovisoli GN=WN71_15135 PE=4 SV=1
-HLYEVAWTAVTAT--A-PPPAEWAVVGDVPLVPG----LHAA-----------------------------GVR----TVAA--DGAGTVVRFWPDPAC
PPGRPA----AVR-AFAATALAEVQALVALRAPARTVWVTRGAVGAAGDAVPGLAQSVLWGLARSARAEHPDLGLTLLDLDGADPDP------ASLVALG
-LPDESEIAVREGTPLAPRLIRARTPQPPAARHPVVPTDGTVLVTGGLGAVGLHIARLLAEHGARRLLLTSRQGGDDPR--AADAIAELA----ALGAEA
EVAACDVADAGALAALL----D--GVPLRGVVHCAGVLDDGVVTELTPQRLETVLRPKADGAAHLHRLTAGRPLELFLLVSSAAGVAGSPGQGNYAAANV
FLDQLAHHRR-AMGLPAVSVSFGAWAGEGLAAAHADLARMARLGHRALTPEQGRDLVDLSLRRARPHLVASLDLPRLRESAT------------------
----G----PLWSA---------------------LLPAARTGAEGGRGLADRLAALP----GPERAERVLTLVREEISRALGLASVRPDQPLRDLGMDS
VTAVELRNRIGRRVGVKLPATLLFDHPTADRVTAHLLAGP----------
>tr|A0A0K6KXS3|A0A0K6KXS3_BACAM Polyketide synthase PksL OS=Bacillus amyloliquefaciens GN=pksL_2 PE=4 SV=1
-FYYKPEWTESFIPSKKVPLTGLLLIFAENERQIQELTGLFK-DCTLLFVIRGKEFAVLHDDTICMNHVKKHDYLKLFRYIHDHYQLPEKILHLWSDSQA
DM--SKGDIQKQLENGLFSLLYITQALIELKW-KKIIKLTHIFQT--ENKEQLPLHHALGGLVKTVHQEHPNFHYQIINITQSEGAGAAAIADIYQRECD
EKDIHFEVRYENGRRFTKSYNKAGSF----DLTQPLKHHGNYLITGGLGGLGYILAKHLSEKWKANLILTGRSDLT---EEQEKKIEYLR----SSGSTV
EYIRSDVSKQSDAERIFAFAKEQ-FGTLHGVFHSAGVLRDSFILRKTKEEIDQVTGSKVYGTLWLAEEIKKMKVELLVLFSSTSAVFGSAGQCDYAFANA
FLDQYAAVMTAESAERVVSVNWPLWTSGGMNIDDEVSYMKQELGLDPLDDSDGIQALENSLCQSSEQLIA-LKGRKEK----------------------
--------------IEDVLKRA--GTI----------SFHSEQQEDA------------DLQNDELRQNIISYLKNIMSEELKLSLIDEKQYLEKYGIDS
VMIMRLTKKLEQSIG-RLSKTLFFEYHSISQLAEYFLSHH----------
>tr|X2GUJ4|X2GUJ4_9BACI Uncharacterized protein OS=Lysinibacillus varians GN=T479_05860 PE=4 SV=1
-LYYHTDWVQTDAIRKLLPVNKQYLLIADEAIAAASLKENMEKHHNTICVLHGDEFLKKNTHDYTINQDNKEEWSKLFADVCDSGKKNLNIIYCTTKDSV
QNL----ANNKVNYRAIKALHYLVQVMNEETQGSKIKIVTKDVQKLRHEKKLNLSGSMVWGLAKVMSIEYPEIFGGIIDTDEITFYEN----SDFIHEVL
-GDSVQEVCFRENERYVGRLITHADYKLEKNKKIVLKEEASYLITGGTGALGLAYAEQLVNAGAKNLILISRREPSEH---AKVAIQKLI----DKAVQV
KIVHADVCNDESLIKALDDIQ-FTMPPIRGVVHAAGVLNDKMLIDLNWEDFEKVMNPKVVGTLNVFNAIDKETLDFFMMLSSITSVIGNMGQGNYAAANH
FMNSFATYMN-MNKLPGYTFCWGPWNESGMAADNDISSTMARMGMKTFSKGQGQSIINDFMDQPYELLIADIEWNTLVKSLETAAG--------------
-------KTEFLSK-------LV-SEKDLHVDIV------QD---EKDNFLETLMSL----SGEGQNEILIEKLQSICGKIMGFDVLSIDKAFQEQGADS
LMIFSMRTAINKLLGIDVNVSVFFNYPTIVKLSDYLLSEV----------
>tr|B8I8J7|B8I8J7_CLOCE Beta-ketoacyl synthase OS=Clostridium cellulolyticum (strain ATCC 35319 / DSM 5812 / JCM 6584 / H10) GN=Ccel_0858 PE=4 SV=1
---FKYIWKNSEIAEKAISELGSILLFDRNGELASLLGNANKEGKPCVLVMPGAEFSEQKGNIFTINPEKPDDYKKLLQTLKARQMLPKNIIYKWARTGV
GFD--QADMCSCLKDGIYSVLHLTKALAEQKDKVLLLFVHSPA----G-KGGHPLYSGMGAFFKTLRLENPGFVYKSVEMEQDNK---DDVAQRLINELT
LGVGALEVRYEGKQRLVKAMEEISGQIT--DGKIAIKEGGVYLITGGAGGLGLIMAERLAQRAKIKLVLTGRSDLKQ---DKLLKLKEL----EALGSEI
LYIKADISMKDHAQRLIDEVKAN-FGKIDGVIHSAGIYKSGFVIKKTPEEMETVFAPKIFGAAFIDEVTKDEDMDFFIMFSSISAVAGDLGLSDYAYGNG
FMDDFAELRETMRKGRTLSINWPLWEYGGMQISKESQRFFDRTGLNMLPTRQGLEFFDSVTSMTNIQCLVA---------------------------YG
DR------EKV----KKFIEASFR--D----------T-RNSGKGQA---------V--SMDPKVLLEKTEEFLKKIIADEIDVDQVDSDVSFEEYGIDS
ILIHNFNFKIEKHIG-PTSKTLLFEYKYLKDLTEYFVKNH----------
>tr|F1T732|F1T732_9FIRM 6-deoxyerythronolide-B synthase OS=[Clostridium] papyrosolvens DSM 2782 GN=Cpap_3712 PE=4 SV=1
---------------MDYSEKQRLLVFSNID-KSNF------EGFAKELVYVVSDSKKAQMDEYSVQPELLEDSFYIFNKLEQMEYVPDVILVALNDS--
-------EEIRKTKDYVLSTANLAKCLIQKNKG---KLLFSSM----G-NESGMYSEGLTAFFKTLHIEYENLYFRNIICYEQTT---SDFVSVLNKEIN
YFSSEYKVTYRKLQRTVQTYTDYQ--PE--TQIPYLKENGTYILLGGFGEIGKVIAKHLTEQANVNLILCGRKPEND---KVREFINPL----NQGSTRV
IYKSVDISIKEQLQGLIDNVINE-FGYITGIFNMTGYIEPGFLESKDNGFLRNGVKLKVDATVFLDEITKDINLDFFVNFSSVSALVGDFGLSEYVYANC
FFDEFISKREKLRCGNSISINWPYWQDGGLRMVEDASRFSLTTGLSPLLNKDAITAFDSIMKSNVSQCCVL---------------------------FG
KD------KKM----NDYLESKLT--L----------P-TILQKNIN---------L--SLDNSSVKTIVEQYLTKVIAKELKNDDIDLEDGFQSMGIDS
ILIHKLNRVLSADFS-GVSSTIFFDCKNIDEMVSYFVQTY----------
>tr|A0A0N8SRJ9|A0A0N8SRJ9_PSESX Syringopeptin synthetase C OS=Pseudomonas syringae pv. solidagae GN=ALO46_04004 PE=4 SV=1
DWCQAPAWRPALPPRSDSPLQGPWLVVMRGVAADNSM--LFSLPDSVCIADAGDS----GTAVATIARGDAQAYEQLFNTLAAQDALPSQIIYMAGQAQP
THGE------HAAIRLFTDLMSLVQAYIPHANTTVLSLVTEGACQVDDDEPVNSCVATLSGVVRTLAWELPQIQCRHFDLPLANAAENETLLLQALQHID
PSPLASTLALRKQTFHEPCLRALQVSPP----SQPFEEGGTYVVTGGLGGMGLALASHLAAKAAVTLVLMSRFATV--TDEVGQALQAL----EQQGARI
QHMAVDCADREAFTAALHQVRLQ-HGRISGAIHAAGVQASGLIQLSQATAWAQVMGSKVVGTDVLIEVLRQEPVDFIFLCSSLASVLGGLGQADYAAANA
YLDARAQACR-QEGIPVVSLNWDAWAQAGMRVAYDRPEQAPIDDVRGLTNAEGCQLFELALAQNTAQVIVSKAQD---L---------------------
--------QQLI----EQLQRG--G-------------ATSAGRAT--PL---FD---SGAERVAPRNAVEQEVAQLWQELLGGDMPGVLDNFFDLGGHS
LLGSQLISRIRSRFQQCLTLAEFLDEPTIERIARSLGSGA----------
>tr|A0A0P9V408|A0A0P9V408_PSEA0 Non-ribosomal peptide synthetase/polyketide synthetase (Fragment) OS=Pseudomonas amygdali pv. mori GN=ALO63_04931 PE=4 SV=1
DWFYQRQWQRVRRLGTQPIERRDRLVVCSHERVDAALLGCLQVYRHVIEVQAGNGYQQLGPNLYELDPLDPLAFSRLIAELDQSGQAATDWLHALPLSVG
GVV-NEQSLAAAQWACLDTVSAFLQAWGQRKTALRLWLLSWQACPVNGQ-VMRPELAALAGITEVAPQEYP-IRCHWLDLPTAQWGTQARQLATLLAEPT
--SLPRRMAIRDGYLWQPQLQPSSLALPT-VVSNLLPVNGTFLVLGGTGGIGRTLCEHLLQSSQRRVVLLSRRGECP---------QELG----DYAARI
DSVQADIADLARWPKVLEQLRER-YGHFDGVIHAAGTGAGSLIRQRDAHLLSEAMASKTRGMLAVEALIEQMTPGFVLYCSSMSALFGGAGHLDYAAASA
VLDGFAHYRPNENGCVRLGINWDIWRETGMAAASGIGDEAHQRLAVGMSAQEGCQVFDAAMTAQLPQLLISTDLNTA-----------------------
--------RQFYPA-------RHSG---AGLTL-----------VDT-------------APAVAAETGLPERLHGCLCKWLGVSALDPDDSLYELGADS
LTLLDLIDELQAATGVVFQLSQFSHKVSLREVLALVQSA-----------
>tr|I2NBN3|I2NBN3_9ACTN Type I polyketide synthase OS=Streptomyces tsukubaensis NRRL18488 GN=STSU_00540 PE=4 SV=1
DWRYRITWQPSGLHPDSPVLSGTWLLVGHDPQ-APAIAALTRHGADVLTVAPGD-----------LDPAV-------LA-------NAAGVVSLLALDET
PDTR-----HPWVASGTAATLDLVHALHRAASTTPVWLLTRGAVRTTADATTSPAQSAVWGLGRAVGLEHPGLWGGLADLPAEFTAE---TGTRLAAVLA
DPGHEDQIALRGNAVLVRRLSRALP-AP--APRRPWSPRGTVLLTGGTGSVGTHIATWLARQGTRRLVLTSRSGPSAPGA------AALAAAAATSGTDT
DIISCDLNTPDQVSRLVAWTQ-ASGPALSTVFHSATVATLARVEDTDHDNLAQALGAKAAGAVHLDQATTGLDLDEFVLFSSISATWGSNDHGAYAAGNS
FLDGFAEARR-SRGLPATSIAWGVWNTQDWDQAPGTPGRLRRQGMNFMDTDRALTALGHILTHDETFIVADITWDTFAP------------------VFR
AAR----PRPLLDTIPEARE---EPPTPT-------GPAGQGGQAEHGQYATLLAR----MPHTERHRTLTELVRSHAAAVLGHTDVPAERPFRDIGFDS
LTAVELRNRLNTTTGTRLPATAVFDHPDPTTLAREILTRL----------
>tr|A0A077QMG8|A0A077QMG8_XENBV Uncharacterized protein OS=Xenorhabdus bovienii str. Intermedium GN=XBI1_2660056 PE=4 SV=1
----------------------------------------------------------------------------------------------WCLPKG
ALSDSLDNFIHDQENGLLFGLRLFKGLAELGHPLQLTVITWQTQAINN-EILCPAHASVHGLLGSVAKEYGHWAIRVVDLSLEEGK------QQLEQSLP
DDPAGNAFAHRQGQWYHQRLTPVPLPAQS-PVSSAYKHNGVYVVVGGAGGLGETWSEWIIRNYQAHVVWFGRRASDA---DIQAKIRRLA----SLGPAP
LYIQADVSDRESLDNAVKQVHAA-YGKVNGIVHSSLVLNDRSLSNMDETSFRVSIAAKIDTSVRIIQAFDHDPLDFALFFSSLASFSKPAGQCNYAAGCL
FTDAFAHYLSQVKNYPGKVINWGYWGSVGVAVDEKLRTRMRASGLESIEPAEGMAALNHLLAAPFNQMVVKVNDTNA-IARLCGMDSGF-QTMAVNTLPS
RDETPVISDTLSQHQVDLMREQISPAF------------------SSVN-------LQQETDKAQLSDRVRTAVRECIAAVLRISKIRDNQAFAEYGVDS
IIAVNLINQINKQCGLSLNTTVIFDYSTAEKLVSHIITQH----------
>tr|M1MCR4|M1MCR4_9CLOT Polyketide synthase PksN OS=Clostridium saccharoperbutylacetonicum N1-4(HMT) GN=pksN PE=4 SV=1
--MYHYVWKKNNKKMMGRSKVGSLLIFDNDKILAQEFR----YANDITYVLSGNKFRECQNGVYEIATSDEESYFKLFDELRRRGKLPNQIVYKWTYIGN
ST-------GENVRTAFYAMLHIARALVKLKDKVKLLYLYQDENN-----HEAVMNDALSGFVKTLQMEHPNLYFRIIKIKGIQYS----IKDLIESELQ
V-DDTNTVYYQDNTRYMEQLIRDDVKHL--DSKVPFKERGTYLITGGMGEIGLSLARYLASNFRANLILTGRSVLDAK---KQENLEELR----MLGANV
SYISVDMSKRKDVMRMKEQIKDQ-FTTIQGIISCAGVVRDSFIINKTMLQIEEVLRAKIDATIIMDQVMKDEKLDFFLLFSSISH-LGNIGQADYAVANS
FLNSFASYRKKERYGKTVSINWPIWEQGGMHMETAVERQKERTGVYPLPTQVGLEAIRNSLMQENDTVLIYGEGKKL-----------------------
--------QKFVSH----LNSRE-----------DQM-----GE---KEI-----EVKSEMNQKELIESVMTFLQNTAEELIKVNDLNIDKDLSECGFDS
ISNTDYTNKINDYYGLEVMPTIFFEMPTVRALCNYLIKNY----------
>tr|A0A0D0HC25|A0A0D0HC25_9BURK KY49.ctg7180000000020_quiver, whole genome shotgun sequence OS=Burkholderia sp. MSHR3999 GN=KY49_5839 PE=4 SV=1
--LHAPRWQPVDLPSDADEAGRPWLIVGDAAAAGDAFAALAARGARVERLDLAGA-----------DAAGLAALERRLLDYAAAHAEPFGLIHVHPAGSP
GAA--------AADL---AVVRFVAGLSA-GRLHRALLVTRGAQPVAGEA-PGASGAALWGLGATLQAEAPQQAVTLVDLDAGRCDA--ADADAVLRAAD
AARWPDHLALRAGRCHQRALGPVHAL-----GPMAIAGDGTYLVTGGLGGVGRRVVEFLHARGAGRIVVLGRGVPAEPPA----WLAALDA----RRAAL
EWVACDVTDAARVAAVVGALARE--ARIRGIVHAAGVLDDARLVEQDAARLQRVAAPKLDGARHLLDALPAASLDFVWLFSSITALFGGAGQANYAAANA
ALDSFAHALR-ARGVPATAINWGPWRDTGMLARVAPDATYARLHADPLDPADAARWFDALLAIDDAQCSV-VHWRLDALAQ-A-----------------
---------RR---LPVLLRPLA-AK----VAKAEGGAAA-TASADAGSYLQRLAG---A-LPAERAALARRFVAEQIAAITGIDAIAPAAPLSGLGMDS
LMSVALSDALADCLGIAYSATLLFDHPTLDALAAHVLAGN----------
>tr|Q0B303|Q0B303_BURCM Beta-ketoacyl synthase OS=Burkholderia ambifaria (strain ATCC BAA-244 / AMMD) GN=Bamb_5925 PE=4 SV=1
--LHALRWRRVDPPS-VDEAGRSWLVVSAAGASGGAFAALGARGARVERLDPRDH-----------DAAGLAAFARSLADYAAARAEPFGLIHLHAD---
--A--------AVDL---AVVRFLAGLPA-GCLHRALLVTQGAQAVAGEL-PDLSATVLWGLGATLQAEAPQQAVTLVDLEAGLDAL--VGIETVLNAAD
APAWPDHLALRAGRWHQRVLAPATAR-----GPLTISGDGSYLVTGGLGGLGRRVVEFLHARGAGRIVVLGRTLPAEPPA----WLAALQA----ERAVV
ELVACDLSDAARVASVPGTLGRE--LPLRGIVHAAGVLDDARLIDQDAARLRRVAAPKLDGARHLLDALAGASLDFVWLFSSITALHGGAGQANYAAANA
ALDGYAHTLR-ARGVPATAINWGPWRDTGMLARVAPEATYARLHADPLEPAEAARWFDALLATDGAQLCV-VHWRLDALAR-V-----------------
---------PG---LPALLRDLV-TA----ATSVAT-PAT-AGQAGPASYRQRLAD---A-LPAERAALARRLVAEQIALVTGIATIEPAAPLSILGMDS
LMSVALSDALAHCLGIAASATLLFDHPTLDALALHVLAAN----------
>tr|A0A0C2DDB4|A0A0C2DDB4_9DELT Malonyl CoA-acyl carrier protein transacylase OS=Enhygromyxa salina GN=DB30_02711 PE=4 SV=1
--------------------PEELLLISPDDGLARGLERAAARLTACPLRKSAARSTRLEADRFELDLTCEGDVDALFEDLARVRRLPDTVVL----DAR
GED-------NVGADHLHSLLYLCRALVRAKPSVRVLHLRNHARGL-----ADGVHAMVGGFARTLARENPQIQLVAIACDLDTED------AVLRAELG
HYAAMAEVEHRGGRRLVREMVEVPTPRAYTETQSMIREHGRYLISGGMGALGLAVAQHLARDHAASLVLLGRSPMTA---DIRARLESL----SAAGGDA
IYMQADVSERAQVEAVFAELGRR-DLQLDGIIHAAGLIEDAFVLRKRPESLDRVLAPKVAGALNLDAASTDHPLGLFVLFSSVASLMPNQGQCDYAAANA
FLDHFAAQRELERRGATLAINWPLWAKGGITVAPEERHLWTEFGMHPMATAVGVELFARLTCDAGSPHYAPIEGDRDK----------------------
--------------IEAHLRIA----AASAVVEVDE---TS-------------------TSSSSLSGRIDRMLAALVDREAAPRGHRGAPTLSELGLDS
LGMIRFADRLSSELGLEIKPSIFFEYATVPSLVAYLAQRKPA--------
>tr|A0A0C1ZNA2|A0A0C1ZNA2_PSEFL Thioester reductase OS=Pseudomonas fluorescens GN=NX10_20985 PE=4 SV=1
DWFHQRQWVRTRRLSATAAGSREVLILCSHAPESTLLASLNAVYRRVIQVRTGNGFKRLSADSFELDPLDTEALSRLLTEVAEPALGELDWLHALPLAVS
GAV-NEQSLDLAQWACLDTVSALMQAWGQTTTRLRLWLMSWQACPVDGE-VQRPELAALAGITEVVPQEYP-VRCHWLDWPSSRLGAHAGELAALCVD--
PVSLPRRMAVRDGYLWQPRLMPQPLTGPA-TTSGLLPEDGTFLVLGGSGGIGRTLCEHLLQAPARRVVLLSRQGQLP---------VSLA----AYALRI
DCIKADIADLPRWPQVLDQLAVR-YGRVSGVIHAAGVGAGSLIRHRDARQMAEAMAAKTRGMLAVEALIEHLTPDFVLYCSSMSALFGGAGHLDYAAASG
VLDGFTHYRPNATACLRLEINWDIWRDIGMATTSYSAAHLE-HLTVGLSAEEGCRVFDLAMAMQLPQLLISTTG--------I-----------------
------DTARRFYP-------------VRHA-------------VAAV--------V-----EAPKGVDLSTRLRECLCKWLGVAELEDDDSLYDLGADS
LTLLDLIDELQAATGEVFQLSQFSHKVSLSEVLGLVSTAT----------
>tr|A0A0N1NA15|A0A0N1NA15_9ACTN Amino acid adenylation domain protein OS=Actinobacteria bacterium OK006 GN=OK006_8448 PE=4 SV=1
NWLHQPHWVRLRRATVADAGRASAVVVVASNTPRTALAPFEAVASHVIRVHPAGAFARRGPDAYDADPADPASLRELLNALGVPATVDTEWVHALPLDVT
GPV-GPGTLQHARHTCIDSTAALAQALT--NGSPRVWWLSYGARPVTET-VDRPELALLAGPVEVAHQESA-LNGHWLDLPDGDLTRWAGHVASVVAD--
GPALPRQLALRQDYWWRPGTIPVPEPKGT-QSLVPSGADTVHLVLGGTGGIGRAIAAWLLEHTRGRVLLLSRNPRLP---------EELN----RWANRI
GLVPADLATMPVHE-VAPAVADH-TSRLDGVIHAAGLGHGGLLVRRDATAMRDAAAVRERGALVVEHLIGAFRPEIAVYCSSMSALLGGVGQSDYAASAS
LLDGFAHHRAPGTTTVRIGIDWDIWSETGMATRVLNTRHQA-HLAVGLTVEEGKAVFAHALALQLPQLLVSTTD--------I-----------------
------ELSRAFYA-------------PTEI-------------ADRSSCS---GPV-----HPTDGGERADAMARVIQDLLGVDELAPEDSLYDLGADS
LTLISLIAQIEDDYGVEFDLASFSHRVSLAEILKHIEAAL----------
>tr|I9B3E8|I9B3E8_9FIRM Thioester reductase domain protein OS=Pelosinus fermentans B4 GN=FB4_2641 PE=4 SV=1
--------------------------------------------------------------IHHISRKDRSTYEQVFQSIREDYGDVDGVLYLWPLEDV
TCI-----------EDYSAIVYLLQSIAAVK--LKAKRVLLGAQFEMGLE--RCYLDSWIGFERSLGLVLPNTQVAVMYQESSGQDFMKDWLTKLWSELQ
T-EKIQSVFYQEGKRHVYQIQETSLETG----SSLLQAGGTYLITGGCGGLGFLFARHFANTHAVNLILTGRSALDE---EKQAKVRELE----ALGSHA
LYLQADSCDVSSMKIALGQAKEK-FGEIHGVIHAAGLAGRQSIFEKDMTGFMRIIEPKIKGTLVLDEVLQEEALHFICYFSSSSAILGDFGSCDYAIGNR
FQMAYAHYRQEKQYGKSLVINWPLWKDGGMEVGEESKFYLKSSGQRFLEAEEGTLIFDSILSQNKTQLLVGQ-PSRIK----------------------
---------RFLGL-T---QDDV---------SLSLLSLDSSAKGRRPEM-----------KGLNLEECVEWDLKEYISQLLKINKLDKEDNLADFGFDS
ISLAQFAALLRSHFGIEVTATLFFGYSTIKKLTQYFVTDH----------
>tr|I9NV79|I9NV79_9FIRM Thioester reductase domain protein OS=Pelosinus fermentans JBW45 GN=JBW_00862 PE=4 SV=1
--------------------------------------------------------------IYPISRKDPSTYEQAFQSIREDYGEIDGMLYLWTIEDA
TCI-----------EDYSVIVYLLQSIAAVK--LKAGRVLLGAQFETGLE--RCYLDSWVGFERSLGLVLPNTQVAVTYQKSSGPDTMEDWLTKLWSELQ
T-EKLQSVFYQEGKRYVYQIQETFLETG----SSLLQAGGTYLITGGCGGLGFLFARHFAKTHAVNLILTGRSALDA---KKQAKIHELE----ALGSHA
LYLQADSCDVSSMRSALAQAKAK-YGEIHGVIHAAGLAGSQSLFEKDLAGFKKIIEPKIKGTLVLDEVLQEVALHFMCYFSSSSAILGDFGSCDYAIGNR
FQMAYAHYRQEKQYGKSLVINWPLWKDGGMGVGEESKLYLKSSGQRFLEAEEGTVMFDCILSQSTIQLLVGQ-PSRIK----------------------
---------RFLGL-T---HDDV---------SLSLLSLNSPSRGRRPEM-----------KGLNLEQCVEWDLKEYISQLLKINKLDKEENLADFGFDS
ISLTQLAALLRSHYGIEVTATLFFGYSTIEKLTQYFVTDH----------
>tr|A0A0M4LMR7|A0A0M4LMR7_PSESX Thioester reductase OS=Pseudomonas syringae UMAF0158 GN=PSYRMG_24725 PE=4 SV=1
DWFYQRQWQRVNRLRINPTEGREVLVVCSHERLDTTLGSLQSVYRHVIEVQAGNGYQQLGLNRYELDPLDPVALGRLISALDQSGQTASEWLHALPLSVG
GAV-DEQSLAAAQWACLDTLSALLQAWGQNKTALRLWLLSWRACPVNGQ-VMRPELAALAGITEVAPQEYP-IRCHWLDLPTAQLSTQAPHLAALLAEPV
--LLPRRMAIRDGYLWQPQLLASPLAAPT-AASNLLPANGTFLVLGGTGGIGRTLCEHLLRSSQRRVVLLSRGGGCP---------KELD----AYASRI
DSIAADIADLARWPTVLEHLRER-YGHFDGVIHAAGTGAGSLIRQRDAQVLSEAMASKTRGMLAVEALIEQMTPGFVLYCSSMSALFGGAGHLDYAAASA
VLDGFTHYRAHANGCVRLGINWDIWRDVGMAAASGVGDDAHQRLAVGMSAQEGCRVFDAAMTAQLPQLLISTDPAT------------------------
--------ARQFYPVRHSAGSTL---------------------ADTAP---VL---T---ADTAAPDCLPEHLHDCLCKWLGVSALQPDASLYELGADS
LTLLDLIDELQAATGVVFQLSQFSHKVSLAEVLALVRAS-----------
>tr|Q9Z5F4|Q9Z5F4_MYXXA Ta1 (Fragment) OS=Myxococcus xanthus GN=ta1 PE=4 SV=1
VPLFVPTWQPWSEGASNASALRHLVVLCEPLDLGAGASALASTADRRIEVVRTSPSARLD-ARFM--AHASAVFERVKALLSERLTAPV-----------
----------------------------------TLQVL------V-PEERDALALSGLGSLLRSVSQENPLVRGQLIRVQGSVSA--SALVDVLVK-SA
RAGDVTDSRYHAGQLSRCEWREARVAKG--DASRFWREDGVYVISGGTGALARLFVAEIGKRATRATVILVARASSAEA--------VD----GGNGLRV
RHLPVDVTQPNDVNAFVATVLRE-HGRIDGVIHAAGIRRDNYLLNKPVAEMQAVLAPKVVGLVNLDHATRELPLDFFVTFSSL-AAFGNAGQSDYAAANG
FMDGFAESRAALNAGRTVSIRWPLWENGGMQLDSRSRVLMQRTGMAALGDEAGLGAFYRALELGSPGVAVWTEAQ-------------------------
----------RFRELS----VSVSPAPPPH----------------QVAL----D------AVVSITEKVETKLKALFSEVYEERRIDARQPMERYGIDS
IIITQMNQALEGPYNA-LSKTLFFEYRTLAEVSGYLAEHRAEE-------
>tr|A0A0P9I3G9|A0A0P9I3G9_PSESX Amino acid adenylation (Fragment) OS=Pseudomonas syringae pv. aceris GN=ALO91_04572 PE=4 SV=1
DWFYQRQWQRVSRLRTQPTEGRDVLVVCSHERE-ATLGSLQGVYRHVIEVQAGNGYQQLGPNRYELDPLDPVAFGRLIATLDQNGQLPL-----------
----------------------------------SVGGS------V-DEQSQWACLDTLSALLQAWGQQACPVNGQVMRPE---------LAA-----LA
GITEVAP----QEYPIRCHWLDLPTTPT--AGSNLLPANGTLLVLGGTGGIGRTLCEHLLQSSQRRIVLLSRGGECPK---------QL----DAYASRI
DSIAADIADLARWPTVLEQLRER-YGHFDGVIHAAGTGAGSLIRQRDAHVLSEAMASKTRGMLAVEALIEQMNPGFVLYCSMS-ALFGGPGHLDYAAASA
MLDGFTHYRPHANG-VRLGINWDIWRDVGMAAASGVGDAHQRHLAVGMSAQEGCRVFDAAMTAQLPQLLISTDPD-------------------------
----------TARQFR----HSAVATLADT----------------APAL----A------ADTEAPDRLPGHLNDCLCKWLGVNVLQPDASLYELGADS
LTLLDLIDELQAATGV-VFQSQFSHKVSLTEVLALVQAGTAAD-------
>tr|A0A0K6LAH5|A0A0K6LAH5_BACAM Polyketide synthase PksM OS=Bacillus amyloliquefaciens GN=pksM_2 PE=4 SV=1
--------------------------------------------IDVIFIAQGDRYEALSAGRCQVVREDPQSYVNAFADIQKEYGEASAILYLWALEDK
SCI-----------EDYSCIVHILKAMAETGQPERLLLAGEYAS---GL--ERCYLESWIGFERSLGIVLPKTSVTGH-FRKAG-AAITDWMRTIWDELK
A-ETDHTVFLEEGKRYVYHTEPTGLTKE----NSRIRTGGTYLITGGLGGLGYLFARHLARNYQANVILTGRSPINE---EKKEKMKDLE----NLGAGV
LYAEADVCDPIGMGDCIKRAKER-FGAIHGVIHAAGIESRTSVFENEIGNFRSTLDPKINGSLLLDEWLKNETPDFICYFSSTSAVLGDFGCCDYAVANR
FQMAYARYKNEQESGNAFVINWPVWKNGGMAVGGETGMYLKSSGQRLLETDEGIELFERIISQDNTQCIAGK-RSRA-----------------------
--------ERFL-GIRRD--DSL--------------------K--TDALLET---VSRRIPEESAEKRLEADLKELIHSLLKIDKLVLHKNWAEFGFDS
IYLAKFAALLSSHYGIEVTPALFYNYATLGDVISYYLTEH----------
>tr|S5TP53|S5TP53_PSEFL NRPS (Fragment) OS=Pseudomonas fluorescens GN=nrps PE=4 SV=1
DWFYQRQWVRVRRLNTVATERRETLVICSNETLDTTLLESLNTVYRVIHLRAGNGFKRLGTDRFELDPLDAQALSRLLDELAEPALGELDWLHALPLSVT
GAV-NEQSLAAAQWAGLDTVSALMQAWGQAATTLRLWLMSWQACPVDGEV-IRPELAALAGITEVVPQEYP-VRCHWLDWPTFRMG-----AQELATLLA
DPSLPRRMAIRDGYLWQPRLIASPLPASV-PMANRLPMDGMFLVLGGTGGIGRTLAEHLLQAPQRRIVVLSRRG-------------ELPAALAAYGSRI
DCVQADIADLANWPAVLEQL-ARCYGRFAGVIHAAGVGAGSLIRQRDARQLGEAMAAKTRGMLAVEALISTMNPGFVLYCSSMSALFGGAGHMDYAAASA
LLDGFAHYRPSASDCVRLGINWDIWRDIGMATTSGTGDAAHQEHLVGMSAEEGCRVFDLAMTTQLPQLLI------------------------------
---------------------------------------STTGIDTARRFYPVRHGAVIAPVNVPEVLDLHSHLHESLCKWLGVTRLDDDDSLYELGADS
LTLLDLIDELQAATGVVFQLSQFSHKVSLQEILALVDA------------
>tr|A0A0Q5RTF8|A0A0Q5RTF8_9BACL Uncharacterized protein OS=Brevibacillus sp. Leaf182 GN=ASG16_06530 PE=4 SV=1
----------------------------------------------------------------SIDKWDSSGFERVLADVNR-TEAVEAILFLWPLETA
PSAQM-----------TDELTALIQGMHASLTSIRLLVAATCS-----TEIEHCHAESWIGFERSIGPLMKDVRMSVHLFDGFERSSGRNLWESLWIELG
QD-MVRSSLYAGGERHVCSVRETRLQP----KATKFRQGGIYLITGGFGGIGMVVAEHLAKTYQAKLILTGRSSIDARK---RSMMKKL----EAAGATV
FAFQADVCDYAAMKQGLAEARAALSGSINGVIHAAGTESGRSILEKKTEQFHEVIQPKITGTLLLDELLQEERLDFVAYFSSISAVLGDFGSCDYAVGNR
FMTAYAKRASRRHGGSIVSIQWPLWKDGGMSVGDPTEMYLQASGQRALEAEQGIALLELLLAQDEPNHMVGN-RESVRRSLGL-----------------
--------EPT-------VEQ-------EVVKPVKAAPLTSIAKRAER-------------AELNVEQLLEEDLKEHISRIVPIDRIDKEQYFSDFGFNS
ISFAELASSLTKHYCIDLTPAVFFSYPTVEKLIHFYLREH----------
>tr|A0A0Q5RHV8|A0A0Q5RHV8_9BACL Uncharacterized protein OS=Brevibacillus sp. Leaf182 GN=ASG16_06490 PE=4 SV=1
---------------------------------------------------------------ITVNVGEEDDIEQIAMVLARFG----IIDHLWLAPPS
EFLLHDDSLLAKQKAGVLLLFRLIKALLHAGKRLSVDVLTFQTQRAYTGDRINPVHASVHGLIGALAKEYPNWQIRLLDLEPGWE----TSIETLLT-LP
PDTEGNTWCLRGREWLCQRLAPVNLAPGM--QHNGYRKGGVYVVIGGAGGIGEVWTAYMIRRYQAQIVWLGRRRQDES---ISASIERVS--VSTTGPKP
IYIEADAADTQSLDHAYQVIKAR-FGAIHGVIHAAIVLRDQSLANMQEDDFRAGLGAKIDVSVRLAQIFRKEPLDFVLFFSGMMSFARRAGQSNYAAGCT
FKDAFAIRLARDWPCAVKIMNWGYWGSAGIVASDEYRARMELDGIGSITPSDAMEALETLLASPIEQMAIKASKSVLEA------------------GFA
S-------ERLIDVIFDT--PGFNGDYR-SMVELPALPDLITGMIER-------------GQPVRPTGQAEPILHDLISRLLNVEEIDPNAEFAEYGLDT
VQLAELLSKLNRRFMVEVEMQAFTDWTTLNQIAQAVSR------------
>tr|A0A068PCS5|A0A068PCS5_9DELT CalA OS=uncultured Candidatus Entotheonella sp. GN=calA PE=4 SV=1
----------------------------------------------------------------------------------------------------
-------------------------------SPYQLVYVTLGLQHFRA-ERMSLAGAKFAGLVKMMSAEYRHLSARCIDIDRALCNDPRAFEAVILGECH
MPLEETEICYRHGDRFVPTLEVGEPARDEVNRRFSITADGVYVISGGTSGIGLEIARYLVSRGARRLVLMGITPLPPRDQWVSARLAALNALA-AELERL
DIYTGTLSNAAALANFFNRIRRE-SGPIKGVVHSAGVYSDSAFVTRDIEDMRQILEPKVNGMEHLAECFADDPLDFFVSFSSLTSFIPARGISDYAMANA
FLDFFSAWQHHHQRTHYRAITWVDWNETGVAQRMTVEKNLERVGLSSFSNEEGRHFFEQAMLLPNHHVLPCIDAARLNAARLLHRNAESETPHPVV---K
A-------APMGAALPNMDRDDVSPDWKARYVSFDQLK------QQDPTLIQRVYAIGNDKPSESDGEPISEIVYRALLDVLKIDGIDEHESFANYGLDS
ISAMVFSTRLEKRLDMEIPPHWLIDFPTIQTLSEQIQQNQ----------
>tr|L8JWQ4|L8JWQ4_9BACT Malonyl CoA-acyl carrier protein transacylase OS=Fulvivirga imtechensis AK7 GN=C900_01919 PE=4 SV=1
----------------------------------------------------------------------------------------------------
-------EIIAGQEKGVITVFRTVKVLQKLDKALQWTLITGNTQHVKEDDRVLAAHAGVFGMAGSLAKEFPGWNLRLLDVDSLGSVTATECLSQDW----
-DRQGDGLAHRQGKWFSPGLTRMDALQPS---SPIYKQKGVYVVIGGAGGLGEVWSRFMIEQYQARIVWIGRRKADD-------TITEKIKLLSGMGEAP
VYISADATKAAELERARKEILKR-YPVINGVVHSALVLKDQSLLNMDEAAFKAGLSAKVDISVSMDAAFGALDLDFILFFSSIVSFFKTPGQSNYAAGCA
FKDSFAHSLGQQRKYPVKVMNWGYWGSVGVATDELTRQRIAQMGIGSIEPEEGMSALQNFVDSGRQQVLIKVLNNQILQAITLPEEGAQPIETAPVAVPN
-------AQKMMTKYDEPVRSGSNGHI------------ATNGKQTDSILQRSHDV-----SEQMISDYVQQTITETLADGLKIEAINADTSYADYGVDS
IVGVNLIRTINKAFGIELETISLFEHGSVNKLTQFVVSH-----------
>tr|C6C2W7|C6C2W7_DICDC KR domain protein OS=Dickeya dadantii (strain Ech703) GN=Dd703_1430 PE=4 SV=1
--------------------------------------------------------------GFHLQPKDTERYQHCFAQLKSAGIAPQAMLYLWPLEER
RQI-----------QDFAALHDLLSSMVATMAPTRLLLAGASHHS-----LERAYLESWIGIERSLTSVLPNTQCAVASVAVGDGTFTRQYVSMLYQELT
G-QNFASVCYEGAERYVLTVQPSPVALARAVAEAGIKQGGTYLITGGFGGLGLIFARYLAQRYSARLILTGRSPMNAER---KAIADEL----TRLGGQV
QYIQADVCDVGAMRFNLLQARQ-SLGSILGVIHTAGLEASEPVFEKSRQAFNAILRPKVEGTQLLDELLMQDPLDFVCYFSSSAAFLGDFGSCDYAMGNR
FQMGYGKHRMAQLRGKTLIINWPFWKEGKMGIRDSTEFYLRSSGQRALESEEGVQVFEQLLRQSEGQVIAGK-PSRVA------------------RFLG
TDEPPV--ARRTEHVSDVSKKRTGNH---------AAPHNP-AQHDRQAVGSRSDLARPSGDAADIRTAVSHVLKTQISQLLGVDRIGVNSSFADFGFDS
ITLASFSRALSQHFEVEITPAVLFGHSSVKRLTEYFCREHA---------
>tr|C7PXR3|C7PXR3_CATAD KR domain protein OS=Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897) GN=Caci_2598 PE=3 SV=1
--YLRPSWTSAPAPAPNVAPPATVLLLGVG-PVAEAVADHLLAAGSLCLAATGA---------------SRADFDLVLADL---GGPADAIVHIPSPDAP
----------------FEPLLWSAVALLAHPERGAVRIVTASDASVPGTV-------ALAAPLRTLALEHSGFAAATVDSATS--------ARHLLDELA
RAERVREVRYVGDERMVRELQEFAPPLAA--DGLALCAGGVYLVTGGAGGLGRIVARHLSSRAPVTVVLAGRSDLDEATR------AELSA-IAAPGSRI
VYERADVSSADDVAELVSRVR-RDHGPLRGLIHAAGVNRDALAVNKDARDIAEVLGAKYDGARHLDAATAREPLDFVVLFSSVAAQTGNLGQVDYTYANA
CLDEFAADREGRRSGRTVSIGWPLWEEGGMAGDAARKLFARRWGSAPLATGDGLVALERAAAAGESCVVV------------------------------
----------------------------------------------DSVLMNAASASPAFVRRPAELADVEALLRTLASGFLLVDHVDLDADLMDAGFDS
ISLTELVGHVNDHYGVDVLPTVLFECVNLAGFARYLVE------------
>tr|A0A0D5DSX6|A0A0D5DSX6_BURGA D-alanine--poly(Phosphoribitol) ligase, subunit 1 OS=Burkholderia gladioli GN=dltA PE=4 SV=1
RWFFAPSWRRGTGAPAAARGDGVHLLFVDRGGRAAPLVDALAAGEDLVVVTPAAAFAGG-GEAYAIDPAGEADYAALAEALRAAGRLPARISYLAGLVDP
EAAAA---DTANRFDGVHGLHAIARAFGPLEAPVLLTAAANGIHAVSGDEFLLPEQAAMAGPCRVIPLEYPHLRCRLVDVELRAGAVLDAAGELLGAELT
TADTEPVVALRGRHRWLQAVEPLPLAAPA---ASVLKPGGHYLLVGGAGGIGSLFAEHAARSPGARLTLVGRSELPAPETWDAAAIERLRA-LRALGAEV
QYLSADVADREAMTRVARTATA-RFGAIDGLVHAAAVAGGRRIAEETPANTEALFAPKTAGLRVLDAVFDLARADFVLLCSSLAAFAPIDGQSAYCAANA
VLDSWAQALR-ARGVKAIAANWNTWREVGMARRIEVPAAFRQLELNCLAAEDGPLLFERLLGARPVQIVTPLDYEAVAAGTA------------------
---------RLARALR----GEGQGAGDDAQ---TGSSTGSQGSTPAAA--RPA----LAVDYVAPASATEQALAEIWRTQFGIAPIGIHDDFFDLGGHS
LLAVQVVATIRQTLQARLDLQALFDAPTIAGLAARIDGARRE--------
>tr|A0A0F6A3D8|A0A0F6A3D8_9GAMM Uncharacterized protein OS=Grimontia sp. AD028 GN=RN22_03865 PE=4 SV=1
SWGTAVLFALATGALAISIGG--SMLALDGKESTTYLRNLLESGATAVLQLPHALYSGE-GADVPTTPNGKIDRKALPDMREAMEKMPLSLSRWHELLQH
PLSAT---RSSNSKDSIEQLHKLANSHDVG-NWLLLAIQA-ATIAYRGYETSLPLAFSVEPKCSLIELATSEQYCEELSLGNKAHHPVDQKSQTLDL---
-----TLVASNDEVTWLFNHDPLGLEAPL---LGVLKAGAAYVPLDSTGKPKGVMISHCCVIDTQRLNLIKDLIQTTPSRWKLLALPQVQA-LWCYGPTV
WSLEEDVTLGRNLPGYQHGQML-PKGAVGEL-----CIGGASLAEKQFVNTEAGFVYRTGDLALLNQDDTISRIELGEIASQIKGHDNVEDA-VVIARNN
VLVAYIVSEG-EPLQKAVSGSENGWIHLSDNQAQNIDVNQNDASFVCNPLRDTAVLLNSTLAGTFSGIEADLAWPHMPLGQS------------------
---------LITHQVN----RSSQGVGQNQI---IAFVAGSDGHTPHHN--HPI----EKVMTNRPLSDVETKLKAIWLSVLDVQDIGLSDNFFAIGGHS
LLAAKVISRITDELGVSTPLKTLFTHPTLAQLADAIETSSRL--------
>tr|A0A068PCE6|A0A068PCE6_9DELT CalC OS=uncultured Candidatus Entotheonella sp. GN=calC PE=4 SV=1
----------------------------------------------------------------------------------------------------
-------------EADLAAVFHLSQTLMQGNKPIRIYYLHSS-----GD-GPRLDCEALSGFLKSAVMENSRHGWTCIDSDGDLVA---NQAQLMIQEWL
APPPFVELRYRRGQRQLRRLEETYPQQP---DAPVFRSGATYLLTGGFGPVGELLCRELAQRYRARLVILSRGALDE---ERRSLCRDL----ETLGASV
HYHAVDIGDRDALQKTYAEVRRE-VGPIHGVIHLARLVEDGPILSKKWSSFQQVIRAKVQGTIYLDACTADEPLDFFLLFSSMGA-FGIRGSADYGYSAA
FQNAFAAWRRQMRGGETTALCWGFWSVDRMPANR--EQTITESGFDPIDMAAAFPMIEAGCSHQNPALMAVRDGDRARRELGLTPSRAELL-ANQLPLWE
QRQRQGSIDDIHELIDAEEISTLDPELVTRLHR-LLFPQTND--LDTP--TEPLESVQMSPTAGPPSLELTDTIRATLAEILEIDDIDENQPFPDYGLDS
ISGMRLTVSLEKKLAREIDAQWLIDFPTVKSLSQQLAKQQ----------
>tr|A0MS29|A0MS29_9GAMM BryA OS=Candidatus Endobugula sertula PE=4 SV=1
--------------------------------------------INIIFVSRGDSYAKKSAQNYIVSSHHKNDYVSAFEEIKKSIGNVEVILYLWPIEDS
NYIPD-----------YTPIVNLLQASQFAQCRFKRCLLA--AQLSH--ALDRCYVESWIGFERSLKLVINDAALITVFREFSEHETIKNWSKRLWQEMH
A-VDFRSIFYQKEKSFVCRIRQISLTAE----RVLLKNKGTYLITGGAGKLGLLFARKLANMQEINLVLVGRSPINN---DIQDCCEKINSL--SLGSKA
LYLQANVCNINDMKRCREKVNQ-CFGKIRGVIHAAGIQHNQSIFEKDFFDFEKVLEPKIKGTLVINKVFNITEMDFICYFSXSSAILGDFGSCDYAIANR
FQMAYTDYQH-QSGGKAIVINWPQWKDGAMGFGEGTKMALTSSGQRLLESTEGFDMFMNFLGQKKYQLLAGK-P--------------------------
--------DRVYDF--------LGITSPL--------VNSSNNTIQTS------------IKEVNIKQLIEEDLQNYINQLLKINQLDIKRNLADFGFDS
IRLKEFAHFLTQHFTIEVTPLLFFEYPTLEKLSTYFTEQYA---------
>tr|M1MRH6|M1MRH6_9CLOT Polyketide synthase PksM OS=Clostridium saccharoperbutylacetonicum N1-4(HMT) GN=pksM PE=4 SV=1
---------------------------------------------NVVFIAAGLESLRLNEDCYTVNADKQESFQQAFRTIVNENDNISKIIYFWPYEEL
A-----------YVSDYKTLLHIIKALAVEQNANKLLLVGQYQNGL-----QRCYLESWIGFERSLGNMIFRTQVNTIMFESDNLQVTEKDAEKIVLEAN
ASNMYKSSVHNDGKRYELEVQPQTMKN----REVAIKRNGTYLITGGMGKLGFLFAKHLTKQYNANLVLTGRKILDE---ERKSRIRELE----ELGGNV
IYVQAGVCNKAEMENVIREAV-QYFTTIDGVLYMAGTANEVNILNKDVETFCQTIEPKIKGIQILSEVLEAYSVDFICYFSSLAAVLGDFGMCDYSLGNR
FEMAYSAWLNRLISKKTIAVGWPLWRDGGMKLSGGSEAYLNVSGQRYLETEEGIALFEQLLSRSNKEFVIAGDKKKI-----------------------
-----------YNNLK--LQNTD-EEG-Q--------TMT-----YSKELKENHQ-----ANTHELVDTIEMDIKKIVNEMQGIEKLDVETYLTDYGFDS
IILFDFARRISDQYKIDINATTILGYPTISQIAQYLAENYT---------
>tr|A0MS28|A0MS28_9GAMM BryD OS=Candidatus Endobugula sertula PE=4 SV=1
---------------------------------------------------------KNSSECFFVNPYDGITYQEALKNIMQVGSEIYNVLYLWAWEDS
H-----------WIESSIPVVHLLQSIKASEIKVRILLAANYKT-----DLQRCYIESWLGFERSLDLVLPSIHLKVFDISNTKKSIANDYTKTLWSELK
T-TTPGSVLYKKDQRYQLSIQSVTLKDAD----SKSILRGTVLITGGCGGLGLLFAQYLAKTQGTDFILVGRSPLN---EEKQQAIQTLE----NLGSRV
YYLQADVCDKTALQHGLVLAKEHCRNALCAVIHAAGIIDNDDIVTKNIDNFQKVLLPKIEGIRILDEVLADEVLDIVCYFSSASAILGDSGQCDYAVANR
FLMSYGNYRNTKRSGKTIVFNWPGWHVDSMLAGDDSDFYLKSSGQRLLEAAEGCELFEKIIDQSKKQFVIPGQRSRV-----------------------
--------KRFLSRIGKYGDIHSTKNIPGVLDLLE-------G-VDKSGWRPEM-------KGFTIFQCIEWDLKSLIVQQLPIHKVETESNLADFGFDS
ISLTAYASTLSNHYNIDVTPSIFFTYPTIARLCDYFENDYK---------
>tr|D2SUD6|D2SUD6_9BACT Trans-AT polyketide synthase OS=uncultured bacterium psy1 PE=3 SV=1
----------------------------------------------------------------------------------------------------
--------------------------------ALDLLYVTKELQAFRAT-NMSLSGAKFAGLVKMLSAEYSHVRARGLDIDGFLYGSIETLRQVLRQELQ
NDLRETEICYRSGERFVPRIEACAHEETYIPSVSYVAAQGVYVVTGGTRGIGLEIAHELVDLGARKLVVMGRQSLPPTTQWEADKLVGLQAL-RQRVEVL
EIYTGALTDGQALRNFFDGVRAS-HGALRGVVHGAGVYSDPAFVQKDLVEMQRVWEPKVKGLEQLMEVVVGDDLDFFLSFSSLTGLIPSRGSSDYAMANA
FMDFVAAFQFHKNRRAWRTVTWVDWHDAGITARSSLEKHLAEVGLSTFDNQQGRALFREVLHGPAPWSLLGVDEEVFRVALLLGRKSEGQSSSPQTSHLA
T------LDDQLTSWEEQ-KQ---RGVPCSYISLDELRSLDDERIDRIY--RLLADEAGEIEGETSSGELATVVRTTLMQLLELPTVDDDEAFQNYGLDS
ISATIFSNRLEQVLGQPVLPHWLIDYPTVSALAQQLEA------------
>tr|B1HQR7|B1HQR7_LYSSC Putative polyketide synthase pksJ (PKS) OS=Lysinibacillus sphaericus (strain C3-41) GN=Bsph_3304 PE=4 SV=1
-LFFEKKWLHYPHDNETLKEGTTWLYFMNKDDEILALKRMTALGIKIIEVLEADKFVQYTSEQYGIDINSEKDMYKLFEHIGVELRNLKGIIHSYTFKHL
DETESKENMEKSQEEGIFSLFNITKMLLEFTHPIQLNVISSLTEQVKDNEKIIPARVTTFGLAKVISQEQPTISSYSIDHDLDGS--SQDIASQLLKELQ
QDHRPELVAFRQSKRYTKVIERQSDDFN--GNEIIVRENGNYVIAGGTGYLGVQLGKFLSEKQNVNIILLARNLLPDRMEWEKELITSIM-EIESRGSTV
TIMECDVTEEHAVKETFAKIRQD-FGEINGAFMLVKQLYHLWIKELKLSQFKKGIHNRVIGTYLVEKELNPEPLDFFILFSSISSLMGTKSASECCAVNQ
YLDSMAGYLN-QKGIKGKTMNFTLILDDKK-----------DFGSTAIPPIDFVDSLNLFFNK-------GYEWSLISRF-DLEQV-HYLK-PVIKIPFG
--------ESFWSE-------------------VEHFNH---SKNNQNESISMEEE---VVKSEFTLSEIEASIREIWKTVLGISTIKEIDNFFSLGGSS
LSALRFVHLFKNKFGLKFEISDLYSNPTFQDQI-----------------
>tr|R7ZDF6|R7ZDF6_LYSSH Polyketide synthase OS=Lysinibacillus sphaericus OT4b.31 GN=H131_12763 PE=4 SV=1
-LFFEKKWINYPYNNTNLKAGSTWIFFMNKDDEMVELKKMAHIGIRVIEVHKSETFVKHTDEQYSIDINSDTDMYKLFENIGLHLKNLKGIIHSYTFKHL
DETESKENMEKSQEEGIFSLFNITKMLLEFTHPIQLNVMSSLTEQIKDNEKIIPARVTIFGLAKVISQEQPTISSYSIDHDLDGG--SQEIATHLFKELQ
QDTRPELVAFRKSERYTKVIERQSDNFN--GNELLVRENGNYVIAGGTGYLGVQLGKFLSEKETVNIILLARNLLPDRMEWTKALITLIM-EIESRGSTV
TIMQCDVTEEHSVKETFAKIRQD-FGEINGAFMLVKQLYHLWIKELKLSQFKKGIHNRVIGTYLVEKELNPEPLDFFILFSSISSLMGTKSASECCAVNQ
YLDSMAGYLN-QKGINGKTMNFTLILDDKK-----------DFGSTAIPPIDFMDSLNLFFNK-------GYEWSLISRF-DLEQV-HYLK-PVIKIPFG
--------ESFWSE-------------------VECFNH---SKDDQDESIPMEDE---AVKSEFTLSEIEAGIREIWRTVLGVTTIKEIDNFFSLGGSS
LSALRFVHLFKNKFGLKFEISDLYSNPTFQDQI-----------------
>tr|A0A0N7MKJ2|A0A0N7MKJ2_SALET Non-ribosomal peptide synthetase OS=Salmonella enterica subsp. enterica serovar Weltevreden GN=mcnC_1 PE=4 SV=1
-----------------------------------------------------------GDNCIIINPESEQHFAKLRAYIAD--SDHDAIIHAASIDNS
D------MLESALSYGFYSLFL-TRSLLNATQFKKFLVLTNGITQLIETDRINAANATMVGAVRNIKHEFSHIKTGLLDVGEVNEHS-TSQIKQVFSEED
SYQVNTLFAIKFGKLWQETYVRINPSEFI--NQDVITDGDVILITGGMGGVALSIAKTISEKHHVTFILLSRNDIYQPSDYVKQKLALIE-QIKCNGSVV
LTHAVDIGNDDSFNRALNKLA--LNKDITGVIHTAGVEPLAP-EHYNIQNVKRALAGKVYGLRNILQYINIDKLKYLACTSSLASILGDVNRIEYCAANS
YLDYLAVDRNKLGSTHVVSINWPGWSDIGIVRNNEEADKLRAISLNAVQQNEGASIFYDLMQQPYSQVVFS----KLDIQL-------------------
------------------LENTL-------FK-----PLTSVE-NDTSRNVVI---------LEEAHTEQEAIVAQLFAEVLGVERLSVDDDFFRIGGNS
ILAIQLSHKISRNLNFDIRVADIFKYRTIRNILS----------------
>tr|A0A0L0JI24|A0A0L0JI24_9ACTN Polyketide synthase OS=Streptomyces europaeiscabiei GN=IQ60_31575 PE=4 SV=1
--------------------DHDWLVLADTGGVADAFAALAARGERCRLVRRGAAYTASGGATFTVDPGSDSDLRRLLADLDRDGGPFGAVLHLWNLDAP
ALAACRTSLTDHTGAGAYSLIALARLLLARGDGGRLHIVTRGAQPALPGEGPEPLGAPAWGIGRVLRHEHPG---KLIDLDPLRQPDDRAEAEALLGEVL
-SDDEEEIALRDGGRRTSRLRPAGLTRP---LPLRLRTDGSYLVTGAFGALGRLLCRTLVRRGARRIILVGRTPVPAREKWADGRAVALLRELEALGAQP
VLATLDITDEDALAGWLDAHRHSGAPPVRGVFHLAGQVRDTLVADLDRAAFDAVHDPKTVGAHLLHRHLRDEPLEHFVLFASIASLLTTAGQTNYAAGNA
FLDALAHHRR-AQGLPALSLDWGPWA-TGMIEELGLDHYLHSRGMSSLSPDAGMAVLERVIAQDHAQLATVVDWPVFLAWY--------PSP--------
--------PPLVVDLA--------------A---AAAPPA--DAVSGNGFLDTF----SAADEETRRALVAERFAALAATVTGTDRIDPATGLGELGLDS
LLAMELRARIHAELGVALPVVALLSGTPAGELAAQLHDGL----------
>tr|H1XP67|H1XP67_9BACT Amino acid adenylation domain protein OS=Caldithrix abyssi DSM 13497 GN=Calab_2572 PE=4 SV=1
--------------------GNRWLVFSDGTSRSEQFIQMLDKGFECFTVIPGEENEFHDDLTLILNPTKFEEAQKIIDPLISD----TEILYLWSLNPE
IPNEKLYALSNALSLKRFWLVLLGDLLFNFASNSRLISQIDVDTP-DPRTLFKALLLPDYEQRLSIRHKISA---PEMSLKTVYEPDVEVEIKALIGIIF
-KTGQRVMGLIDNGFKKYGLTR-DFILP---MPKELTFANSFALLKDFGRFIELNPRDIVYHNLRYNIAFFA--V-DLENLSQRISSEVQKKFESQTYQP
LPAIHKLQKSTSIEKFVLNLEQQSVKSASTLYLVVGSKRYLMNQGVHQIDFDSFSADGIQGVLLNPQHLLGLALDFFISVSRFSLPEKKAGANEF-GLNN
YLLALHKKRL-LAGLPSLHVQLGGAV-PDEM---SI-------------ALGRWSILNELIPVEKGHLITETNWANIFGSK--------PQI--------
--------PPLLRDIL--------------F---KEQPEA--GSEKGAKDIDKKE--VLALNPEERFDVIRDYLTYVLAGVIPASQINHELSLSQFGIDS
LMAIELKNTVESQLGISVPIATLLKGPSINDLTNLTLDQI----------
>tr|J3DKV8|J3DKV8_9BURK Amino acid adenylation enzyme/thioester reductase family protein OS=Herbaspirillum sp. CF444 GN=PMI16_00421 PE=4 SV=1
----------------------------------------------------------------------------------------------------
---------------ALYPVFKASQTLMKQARRLSLYLI---------EESSSPRGGALSGFLGAAMMENPLHTWTIIENNEAPRL--NS-LQLAVREWL
QTATFSQVVYENAERRIKQKVPVLFDGPGLSLDTHFRNGGTYLIAGGFGLIGQDFCKKIAGQFNADIIILSRRQHDDA---IAHFAQEI----AQLGGHL
SYYSVDISDLKALGETYELIKVR-HPRVHGILNLAGSSDTTLILRKTWEDSLEHMLAKVHGTENLDIVSADEDLDFFLLFSSIGA-YGLAGSSVYAYACA
FQNEFARYRDDLRKGKTRALAWGPWISDPVHASSDRREKIHADGFSLIDIEKAFPVIAMSLKHTSAELYVNVDNVCSLLQLGLLDDLASKSTQVEGHDFS
EQETQKAQGRTFDDLAGTLSEELRALDPSSIFQLLELEPTPA--PA-------------RPNTVHAETSLVDSIREVLTSVLELAELDNDEHFETYGLDS
ISGTQVSMRLEKRFKHEIKPEWLVQYPTVKSLSDYLKKHL----------
>tr|H8FPU2|H8FPU2_PHAMO Putative Aspartate racemase OS=Phaeospirillum molischianum DSM 120 GN=PHAMO_20066 PE=4 SV=1
-------------------ADELASILAEISGFDATTAQLTDMGLSLMLLKLGQTVE----HRFGLELRTVNDLAAYIQRHATAVPAPAPVIQTAPPSVP
VMPVAPVALPPMDGAGIAPVLQFLSQVAAQARQQMAWLGQGGLPAAPPAAPVVPVKPPASSIAKPLSEQQRTFVSGLVERHVVRTHS--------SKELT
QDSRAVLADWKHTLSFWGQLKEAKYPIVRSEGARFWDVDGNEYIDVAMG-MGV--------------HFFGHKPAPIHDALIRGTQSALTGAFGNTGSEA
VMVALRLARAVTGRDRIVIFDQDGEIVPVGLGTPAGMIRDVTVLDYGSPEALDIIAAQ---------------------ADSLAAVLMEPVQSPDLQPQA
FLSRLRRLTE-QHG---IALIFDEIHPGGAQAWFGVQADIVTYGK---IVGGGLPI--GVIAGK-ARFIDYIDGGAWQYGDRSG-------PQSAMIYFG
G---------TF------CRN------PA------TMATTLA------ALTVMK---EAGPTLQERVTARTVAFCDALNLWFELKHFSSQWRLVPLGESD
FQPLEIELMIERGVYTWERRINFFSDDDVARVLEVI--------------
>tr|I8U1X2|I8U1X2_9FIRM Amino acid adenylation domain protein OS=Pelosinus fermentans JBW45 GN=JBW_04656 PE=4 SV=1
-------------------GKKTWLIFAQQEGIGDLVAKLTERGETV-LIYPGQSFE----DTFSINS-SQEDLKQLLHT--VL-DVCHGIIHTWSGSND
KNNITTVDLEKAQNLGCLHVLQLIQIIQELRALPRLWLITRGSQAV--GEPVDFIQAPLWGLGRTIAIEQKELWGGLIDLDPEDQGEQ------AADDFV
QGG-EDQVAYRQKTRYVARLKR---HSLDRNNPFYWQRNGTYLITGGLGDMQV--------------ALMGRTELPPRTAWDSGTIKELE----SMGASV
HLAAVDVADEEQLKNFLVSFREEGWPPIRGVVHAAGTVADQLLTECDSGSFNKVLRPKVQGAWQLHQLLKDVPLDFFIVFSSISTVVSSPRLGSYAAANA
FLDALMHYRR-NLNLPALSINWGPWAEIGMAARFNILSSTTSMGINALTPACGLQILDNLINTD-MTVVMDVDWERWRIIYQQI-------GKSELV--A
D---------LL------LEE------SE------AAGTVSN------AINQES---SIRKELGEHYNLLESYLCEQVSQVLGMAKLDVHTSLNSLGLDS
IMAVELKNRIEKALDVMVPMVYFLQGPSIAEMIAKI--------------