>seq_1
DTGTVPEKKRVSSDRRKEKSRDAARSRRGKESEVFYELAQELPLPHSVSSSLDKASIMRLIISYLRMRKLLSTEEPMAEEETDLDAQLNGSYLKALEGFL
MVLSEDGDMIYLTENVNKCLGLAQFDLTGYSVFDFIHPCDQEELREMLVHKTGSKKTKEPNTARSFFLRMKCTLTSRGRTVNVKSAAWKVLHCSGHVRVY
DGCTEETPNGHKEPTVPYLVLICDPIQHPSNIEVPLDTKTFLSRHTMDMKFTYCDERITELMGYDPDDLLNRSVYEYYHAMDSDHLTKTHHNLFAKGQVS
TGQYRMLAKRGGFVWVETQATVIYNNKNSQPQCIVCLNFVLSGIQDEKLVLSLEQMEDVKPVDQEEEEEQEEVKAVVEIRELDMSPAPKEVEEKGPELDV
IKLFTQAAEAQPFVSLYDQLKEEPEALNLLAPAAGDAIISLDFSCPDSEIQLVKEVPLYNDVMLPSTSDKLALPLSTLPPCEPLHVSTISSEAAKAESFP
SSTFTSLRSAEAGSLMDFCFPMDSEMKSDSKLDFVEKLFAIDTDPKNLFTTQAMEDLDLEMLAPYIPMDDDFQLRSLTPEEPLSCGPVKSLQSSPIHITQ
DIHSYPFSPVSAPGSRTASPALLRAPQTAPIIAMRTPQLDKEVSLRTLAAQNAQRKRK
>tr|A0A0R4IFF4|A0A0R4IFF4_DANRE Uncharacterized protein OS=Danio rerio GN=hif1ab PE=4 SV=1
----------VSSERRKEKSRDAARSRRGKESEVFYELAHQLPLPHNVTSHLDKASIMRLTISYLRMRKLLNSDEKEEKEENELESQLNGFYLKALEGFL
MVLSEDGDMVYLSENVSKSMGLTQFDLTGHSIFEFSHPCDHEELREMLVHRTGSKKTKEQNTERSFFLRMKCTLTSRGRTVNIKSATWKVLHCAGHVRVH
EGSEASEDSGFKEPPVTYLVLICEPIPHPSNIEVPLDSKTFLSRHTLDMKFSYCDERITELMGYEPDDLLNRSVYEYYHALDSDHLTKTHHNLFAKGQAT
TGQYRMLAKKGGFVWVETQATVIYNPKNSQPQCIVCVNYVLSGIVEGDVVLSLQQTVTEPKAVEKESEETEE---------------------KTSELDI
LKLFKPENCSLESSTLYNKLKEEPEALTVLAPAAGDAIISLDFNNSDSDIQLLKEVPLYNDVMLPSSSEKLPLSLSPLTPSDSIPALTKLETERT----S
ALPL-RRRHPGPLHPYTCCRRCAVHLSRPSVAVGMPHLF--DPAPHRAAVSSTTEK----CLQ-----------RC------------------------
----------------------------------------------------------
>tr|A0A060XQH3|A0A060XQH3_ONCMY Uncharacterized protein (Fragment) OS=Oncorhynchus mykiss GN=GSONMT00056387001 PE=4 SV=1
------------------------------NYVKFWQINYGLSGRNGLHTYPDSACKRRDTISILMLA-------------GNINFLLTSY--AVLKIYT
CVLILRKAFMF----MVRYICATIFDLTGLSVFEYTHPCDHEELREILVHRTGTKKSNGPNTERSFFLRMKCTLTSRGRTVNVKSSTWKVLHCSGHVRVH
EAPTEQSPIGHKEPPVSYLVLVCDPIPHPSNIEAPLDTKTFLSRHTLDMKFTYCDERITELMGYDPEDLINRSVYEYYHALDADYLTKTHHNLFVKGQVS
TGQYRMLAKIGGFVWVETQATVIYNNKNSQPQCVVSVNFVLSGIEEEKMVLSLEQTEDMRSVKKELVEEEEDEGPEAE---------VSPVLLKEEKVDV
IKLFTQA--DQPLASLYDRLKEEPEALTLLAPAAGDTIISLDFSSPDS-DILLKEVPLYNDVMLPSTSDKLALPHSMLPPNEQPLIPSASVDTKA----G
PDSFGSHSSTEPDSPLNFCFPMDSDISAALKLDLVERLFAIDTEPKTPFTSQGMEDLDLEMLAPYIPMDDDFQLRTLSPEEPPSCGPAQPLESSL-----
----------------------------------------------------------
>tr|A0A097NUX8|A0A097NUX8_CYPNE Hypoxia-inducible factor 2-alpha subunit (Fragment) OS=Cyprinodon nevadensis amargosae PE=2 SV=1
------------------------RCRRSKETEVFYELAHQLPLPHSVSAHLDKASIMRLAISFLRTRKLLATTMNAHACNQAEDGLMDNLYLKSLEGFV
TVVTSDGDMIFLSENINKFMGLTQVELTGHSIFDFTHPCDHEEIKENLSLKS-LKKSKDLSTERDFFMRMKCTVTNRGRTVNLKSASWKVLHCTGHLKMY
DGCPSRVLCGYKEPPLTCAVLMCEPIPHPSNIDAPLDSRTFLSRHSMDMKFTYCDNKVTELMGYSPEDLLGRSVYEFYHALDSDSVTKSHHNLCTKGQAV
SGQYRMLAKNGGYVWVETQGTVIYNSRNSQPQCIVCINYVLSDVEEKSVIFSLEQTEAMLKPPHM--S----------------------------S---
--FFTAEMTAEGRDSLFTSFKEEPDDLAQLAPTPGDTIISLDFG--RFSQQPAPFPSVSSSSMPP--------PGPSSWTGESQKPAPAAAAA----PAT
PSLS-----STPSSPGDYYSSVESD----LRVELTEKLFALETDGNDRAAEEDLSDLDLETLAPYIPMDEDFQLNPIIPESEPLEGAGAGSMGMS-----
----------------------------------------------------------
>tr|Q6EHI4|Q6EHI4_DANRE Hypoxia inducible factor 1 alpha OS=Danio rerio GN=hif1ab PE=2 SV=1
----TEK-KRVSSERRKEKSRDAARSRRGKESEVFYELAHQLPLPHNVTSHLDKASIMRLTISYLRMRKLLNSDEKE-EEENELESQLNGFYLKALEGFL
MVLSEDGDMVYLSENVSKSMGLTQFDLTGHSIFEFSHPCDHEELREMLVHRT-GKKTKEQNTERSFFLRMKCTLTSRGRTVNIKSATWKVLHCAGHVRVH
EGSEASEDSGFKEPPVTYLVLICEPIPHPSNIEVPLDSKTFLSRHTLDMKFSYCDERT-ELMGYEPDDLLNRSVYEYYHALDSDHLTKTHHNLFAKGQAT
TGQYRMLAKKGGFVWVETQATVIYNPKNSQPQCIVCVNYVLSGIVEGDVVLSLQQTVTEPKAVEK-----------------------------------
--LFKPESLNCESSTLYNKLKEEPEALTVLAPAAGDAIISLDFNNSD-DIQLLKEVPLYNDVMLPSSSEKLPLSLSPLTPSDSIPALTK--------DPT
PST--------PNSPMDYGFPVEPDISSEFKLDLVEKLFAIDTEAKTPFSTQPMEDLDLEMLAPYIPMDDDFQLRPS-PLDPLP----SS-------LLQ
EVCSAPVSPFSG--SRDASPVRSSS----------SQLNNREMSPKMLAFQ-IQRKRK
>tr|F7G7B7|F7G7B7_ORNAN Uncharacterized protein OS=Ornithorhynchus anatinus GN=HIF1A PE=4 SV=2
---------------------------------------------------------MRLTISYLRMRKLLDTGDLEA--EAEMEAQLNCFYLKALDGFV
MVLTEDGDMIFMSENVNKCMGLTQFELTGHSVFDFTHPCDHEELREMLTHRNGSKKGREQNTERSFFLRMKCTLTSRGRTVNIKSAAWKVLHCTGHIRVY
DACSNQAQCGYKKPPMTCLVLICEPILHPSNIEVPLDSKTFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMFTKGQVT
TGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYVLSGIVQKDLIFSLGQTECVLKPVESPD------------------------------MKM
TQIFSKAD-PEDTSSLFDKLKKEPDALTLLAPAAGDTIIYLDFGNNE-EQQLLDEVPLYNDVMLPSSSEKLQLALSPLPATEPDKPLRSSADPALNQPAS
PSDATDQSSPEPSSPSEYCFNVDNDMASEFKLELVEKLFAEDTEAKNPFSAQDT-DLDLEMLAPYIPMDDDFQLRSFDQLSPIETGSAIAVSPSPGHT-E
TTGAPA-SPYGGARSRTASPARAKGPRSPVTLSKRTTALDEELNPKMLALQNAQRKRK
>tr|V8NR02|V8NR02_OPHHA Hypoxia-inducible factor 1-alpha OS=Ophiophagus hannah GN=HIF1A PE=4 SV=1
----SCEKKRISSERRKEKSRDAARCRRSKESEVFYELAHQLPLPHHVSAHLDKASVMRLTISYLRMRKLLDADDLEA--EAEMETQLNCFYLKALDGFV
MVLSEDGDMIYTSENVNKCMGLTQFELTGHR----------------------SKKGKDQNTERSFFLRMKCTLTSRGRTVNIKSATWKVLHCTGHIRVY
ENCNNQNVCGYKKPPMTCLVLICEPIPHPSNIEVPLDSKTFLSRHSLDMKFSYCDERITELIGYDHEELLGHSVYEYYHALDSDHLTKTHHDMFAKGQVT
TGQYRMLAKQGGYVWVETQATVIYNTKNSQPQCIVCVNYVLSGIVQGDLVFSLQQTERMLKPVDSPE------------------------------MGM
MKVLNKSD-VEDSSSLFEKLKKEPDALAYLAPAAGDTIIALDFDND--DEQPSDDVPLYNDVMLPSSSEKLQLAMSPLSASETAKTLCSSADPALNRPAT
PSDGTSQSSPENSPPNDYCFSMDNEISSEFKLELVEKLFAIDPESKNPFSMQET-DLDLEMLAPYIPMDDDFQLRTFDQLSPLEGNTAVTINPKVLPPAP
IISAPT-SPYAKNESRTSSPIRTKGPGAPVTFG-RSPEVNEDISPRIIALHNIQRKRK
>sp|Q9I8A9|HIF1A_XENLA Hypoxia-inducible factor 1-alpha OS=Xenopus laevis GN=hif1a PE=2 SV=1
----VSEKKRISSERRKEKSRDAARCRRSNESEVFYELSHELPLPHNVSSHLDKASIMRLDHQLPAVEKVADAGDLDG--ETELDKQLNCFYLKALEGFV
LVLTEEGDMIYLSENVNKCMGLTQFELTGHSVFDFTHPCDHEELREMLTFRNGPKKRKRTNHREKFLPSYEMYINQS-----WKNREYKVSHYRTHACIY
DNANNQNHCGYKKPPMTCMVVICEPIPHPSNIEFPLDSKTFLSRHSLDMKFSYCDERVTELVGYEPDELLGRSVYEYYHALDSDHLTKPNYNMFTKGQVT
TGQYRMLAKKGGYVWVETQATVIYNSKNSQPQCIVCVNYVLSEVVEKDLILSLGQTASVLIPVESQE------------------------------IKM
PEIFTELNEENNSECLFDKLKQEPESLTVLAPDAGDEIIPLDFSSG---DKPYEDVPLYNDVMLHSTSNKLE-PITPLPAPEMPKPLRSNVDPALNRARQ
PFRYFQSEPS-EPNTPEYCFDVDSEMASEFKLDLVEKLFAIDTEAKAPFYYPGN-DLDLEMLAPYIPMDDDFQLRTFDQLSSLECDSSTT--QSPVHMKE
STSAPV-SPYNGNRSRTSSPVRPKAPGTPP---KRCTILDEELNPKMICFTQCTEKRK
>tr|A0JMU1|A0JMU1_XENLA HIF-1a protein OS=Xenopus laevis GN=HIF-1a PE=2 SV=1
----VSEKKRISSERRKEKSRDAARCRRSKESEVFYELSHELPLPHNVSSHLDKASIMRLAISYLRLRRLLDAGDLDG--ETDLDKQLNCFYLKALEGFV
LVLTEEGDMIYLSENVNKCMGLTQFEFTGHSVFDFTHPCDHEELREMLTFRNGPKKGKEQITERSFFLRMKCTLTSRGRTVNIKSATWKVLHCTGHMRVY
DNANNQKHCGYKKPPMKCMVVICEPIPHPSNIEFPLDSKTFLSRHSLDMKFSYCDERVTELVGYDPDELLGRSVYEYYHALDSDHLTKAHHNMFTKGQVT
TGQYRMLAKKGGYVWVETQATVIYNSKNSQPQCIVCVNYVLSEVVEKDLILSLGQTACVLIPAESQE------------------------------MKM
PEIFTDLSEENNDECLFDKLKQEPESLTALAPDAGDDIIPLDFSSG---DKPYEDVPLYNDVMLHSTSNKLE-PVTPLPASEMLKPLRSNVDPALNRPGS
PSDISSQSST-PSSPPEYCFNVDGEIASEFKLDLVEKLFAIDTEVKAPFTTQET-DLDLEMLAPYIPMDDDFQLRTFDQLSSLECDSSSA--QSPVHMKE
STSAPA-SPYNGNRSRTSSPVRPKAPGTPQ---KRCAVLDEELNPKMIALHNV-RKRK
>tr|B3FMV7|B3FMV7_RANTE Hypoxia-inducible factor 1 alpha OS=Rana temporaria GN=HIF-1a PE=2 SV=1
----TD---KKSSERRKEKSRDAARCRRSKESEVFYELSHQLPLPHNVSSHLDKASIMRLTISYLRIRRLLDAGDMDG--ESEMEKQLNCFYLKALEGFV
LVLTEEGDMIYLSENVNKCMGLTQFELTGHSVFDFTHPCDHEELREMLTFRNGPKKGKEQITERSFFLRMKCTLTSRGRTVNIKSATWKVLHCTGHMRVY
DGCNSQNHCGYKKPPMTCMVLICEPIPHPSNIEFPLDSKTFLSRHSLDMKFSYCDERVTELAGYEPDELLGQSVYDYYHALDSDHLTKAHHDMFTKGQVT
TGQYRMLAKKGGYVWVETQATVIYNTKNSQPQCIVCVNYVLSDIVEKELILSLGQTESTLVSSEPAE------------------------------SKM
PQFFTKLADEEDANVLYEQLKKAPEFLNVLAPDAGDEIIPLDFSSS---ESQYDDAPLYNDVMLHSTSKPPE-LVSPLPVPEKPKPLRSNADPALNKPSS
PSEISNQSST-PGTPAEYCFDEDINVAPEFKMDLVEKLFAMDTEAKAPFSTQET-DLDLEMLAPYIPMDDDFQLRSFDQLSSMETDSATN-VHPPTPNKE
ALSAPA-SPYNGNRSRTSSPVRTKAPGTPP---KRPAVLDDELSPKMIALHNV-RKRK
>tr|T1Q069|T1Q069_PROAN Hypoxia-inducible factor 1 alpha subunit OS=Protopterus annectens PE=2 SV=1
----ICDKKRISSERRKEKSRDAARCRRSKESEVFYELAHQLPLPHNISSHLDKASIMRLVISYLRMRALLSTSNIED---DESDKQLNSFYLKALDGFV
MVLTEDGDMIYLSENVNRCIGLTQFELTGHSVFDFMHPCDHEELREMLTHRIGPKKGKGQSTERSFFLRMKCTLTSRGRTVNIKSATWKVLHCSGHIRVY
ESGSDQTHCGFKEPPLTCLVLICEPIPHPSNIEVPLDSKTFLSRHSLDMKFSYCDERITELMGYDPEDLLNHSVYEYYHALDSDNLTKTHHDLFTKGQVT
TGQYRMLAKEGGYVWVETQATVIYNTKNSQPQCIVCVNYVLSGIVEKGLIFSVEQTKSLMKSVPALD------------------------------ADK
TKHLS----TENPGHLFEKLKEEPEALTLLAPAPGDTIIPLDFNNT--DAQSLDSVALYDDVMLSSDEKV--MDKSPLPASEAAKPLQSDTDPALNMPNS
PSDPASQNST-PSSPSDYCFRVESDIDNEFKLDLVEKLFAVDTEAKNPFSAQVE-GLDLEMLAPYISMDDDYQLRSFDQLPPLESDSVTPSPQSPIRIRE
ISSAPT-SPYSASRSRTSSPVRTKGPGTPVLQ-HRAASSDQELSPKMLALQNVQRKRK
>tr|B6ZGN4|B6ZGN4_CRAGI Hypoxia-inducible factor 1 alpha OS=Crassostrea gigas GN=HIF-1a PE=2 SV=1
----SSNTKRRNSEKRKEKSRDAARCRRGRETEIFSELAEQIPQYSGSNGQLDKASIMRLAISYLKISQIMETQRNN---RHAPCEEFDSLYSKALDGFV
VILSNEGDLIYISESVSKYLGIQQVDLVGQSIYEFVHPCDHEDITDIFHSNGRDKKKKSEEFHHTFFVRMKCTLTNKGKNVNLKSATYKVIKFSGKLVKD
KIKK---ECG-GEGNAPYLLLIGEPIPHPSNIEIPLDQMTFLSRHNMDMKFTYCDDRVKDLLGYNCSDLMNKSLFDYHHAMDSEVIDQAYKNLIAKGQVM
TRQYRFLAKTGGHVWMITQGTVIYNSRTQKPQCIVCVHYVLSGIENPSLILSTAQQVFSQQVPMLPL------------------------------EVK
L-FYFPP-----GVKMPSMKMDETVDLTHLAPTSGDTCVPLIGDDCV-QFS--------PDQ--------------PMPALKEE-------------AIT
-----------PISPMDYTTPLTP-----SVVDAMDKFFSNVETQR----NQATADLDMDMRAPYIPMNKDFSLLPTSSD--------ES----------
-YQDPPKEPRMS-------------TAVA----------SIEQPPDTF---NLQLKRP
>tr|H3BFX9|H3BFX9_LATCH Uncharacterized protein OS=Latimeria chalumnae GN=HIF1A PE=4 SV=1
----VTDKKRVSSERRKEKSRDAARCRRSKESEVFYELAHQLPLPHNVTSHLDKASIMRLTISYLRMRKLLGAGEFEA--EADLDKQLNSCYLKALDGFV
MVLTEDGDIIYLSENVNKCMGLTQFELTGHSVFDFTHPCDHEELREMLTHRNSPKKSKEQHTERNFFLRMKCTLTSRGRTVNIKSATWKVLQCTGHIQVY
ETCKGKTHCGYQEPPMTCLVLICEPIPHPSNIEVPLDSKTFLSRHTLDMKFSYCDERITELIGYQPEELLGRSVYVLYYALDSDHLTKTHHDLFTKGQAT
SGQYRMLAKEGGYVWVETQATVIYNTKNSQPQCVVCVNYVLSGVVEKELVFSIGQAKKTVESVESPD------------------------------AKI
TQLFSKIKPAEDSNSLFDQLKEEPEALTLLAPAAGDTIISLDFSKS--EVQQFDEVPLYNDVMLPSSSENLQLEMSPLPASETTEALCSSTDPALNMPST
PSEHTSQSTP-PKSPPDYCFEVDDDIVSEFKLDLVEKLFAIDTEPKSFFSTQEAEELDLEMLAPYIPMDDDFQLRSFDQLSPLQSGSETN-TVKSIQPSH
INSAPA-SPYSGNRSRTASPVRTSGPGTPVTLN-RTITLNKELNPLTILLHNVQRKRK
>tr|G1NLD8|G1NLD8_MELGA Uncharacterized protein (Fragment) OS=Meleagris gallopavo GN=HIF1A PE=4 SV=1
----QDAFKRISSERRKEKSRDAARCRRSKESEVFYELAHQLPLPHTVSAHLDKASIMRLTISYLRMRKLLDAGELET--EAKMEKELNCFYLKALDGFV
MVLSEDGDMIYMSENVNKCMGLTQFDLTGHSVFDFTHPCDHEELREMLTHRNGPKKGKEQNTERSFFLRMKCTLTSRGRTVNIKSATWKVLHCTGHIRVY
DTCNNQTHCGYKKPPMTCLVLICEPIPHPSNIEVPLDSKTFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMFTKGQVT
TGQYRMLAKQGGYVWVETQATVIYNTKNSQPQCIVCVNYVLSGIVQKDLIFSLGQTECMLKPVESPE------------------------------MKM
TKIFNKDD-LDDTNSLFEKLKQEPDALTVLAPAAGDTIISLDFSSNVIDEQQCDEVPLYNDVMLPSSSEKLQMAMSPLPASETTKPLRSNADPALNRPTS
PSDATSQSSP-PSSPNDYCFDVDNDMANEFKLELVEKLFAIDTEAKNPFSTQET-DLDLEMLAPYIPMDDDFQLRSFDQLSPLESSS-ITVPSSPVHIND
TSSAPA-SPYSGNRSRTASPIRAKGPGAPVTLNKRSTAMDEELNPKMLALHNAQRKRK
>tr|K7FUF4|K7FUF4_PELSI Uncharacterized protein OS=Pelodiscus sinensis GN=HIF1A PE=4 SV=1
----TPLRYRISSDRRKEKSRDAARCRRSKESEVFYELAHQLPLPHTVSAHLDKASIMRLTISYLRMRKLLDSSDLET--EAKMEKEMNCFYLKALDGFV
MVLSEDGDMIYMSENVNKCMGLTQFELTGHSVFDFTHPCDHEELKEMLTHRNGLKKGKEQNTERSFFLRMKCTLTSRGRTVNIKSATWKVLHCTGHVRVY
DTCNNQTHCGYKKPPMTCLVLICVPIPHPSNIEVPLDSKTFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMFAKGQVT
TGQYRMLAKHGGYVWVETQATVIYSTKNSQPQCIVCVNYVLSEIVQEELFFSLGQTERVLKPVESVD------------------------------MNM
TKIFSKAD-LEDSNSLFEKLKKEPDALTLLAPAPGDTIVSLDFDSN--DEQQFDEVPLYNDVMLPSSSEKLQLAISPLPASETTKPLRSNADPALNRPSS
PSDTTNQSSP-PHSPNDYCFDVDNDMANEFKLELVEKLFAIDTEAKNPFSTQET-DLDLEMLAPYIPMDDDFQLRSFDQPPPLESGCASTVSQSPVLINE
IDSTPA-SPYGGNRSRTASPIRAKGPGTPVTLSNRSNPVDEELNPKMLALHNSQRKRK
>tr|G1KSA4|G1KSA4_ANOCA Uncharacterized protein (Fragment) OS=Anolis carolinensis GN=HIF1A PE=4 SV=1
----RRTKGRISSERRKEKSRDAARCRRSKESEVFYELAHQLPLPHHVSSHLDKASIMRLTISYLRMRKLLDAGDLEA--EAEMETQLNCFYLKALDGFV
MVLSEDGDMIYMSENVNKCMGLTQFDLTGHSVFDFTHPCDHEELREMLTHRNGPKKGKEQNTERSFFLRMKCTLTSRGRTVNIKSATWKVLHCTGHIRVY
DNCNNQTVCGYKKPPMTCLVLICEPIPHPSNIEVPLDSKTFLSRHSLDMKFSYCDERITELIGYDPEELLGRSIYEYYHALDSDHLTKTHHDMFAKGQVT
TGQYRMLAKQGGYVWVETQATVIYNTKNSQPQCIVCVNYVLSGVVQGDLIFSLQQTECMLKPVESPE------------------------------MGV
IKILDQTE-LEDSNSLFEKLKKEPDALTYLAPAAGDTIIALDFDSDVVDEQQFDEVPLYNDVMLPSSSEKLQLAMSPLPASEATKLLRSSADPALNRPAT
PSDGTSQSSPESSTPSDYCFDVDNEMASEFKLELVEKLFAIDPESKKPFSMQET-DLDLEMLAPYIPMDDDFQLRSFDQLSPLESSSAVA------HPLE
TNSVPA-SPYTDNSSRTASPVRTKGPGTPVTLGSRSTAANEDINPKIIALHNIQRKRK
>tr|F6RGY6|F6RGY6_MONDO Uncharacterized protein OS=Monodelphis domestica GN=HIF1A PE=4 SV=1
----TNDKKKISSERRKEKSRDAARCRRSKESEVFYELAHQLPLPHNVSSHLDKASVMRLTISYLRMRKLLDAGDLEA--EAEMEAQLNCFYLKALDGFV
MVLTEDGDMIYMSENVNKCMGLTQFELTGHSVFDFTHPCDHEELREMLIHRNGPKKGKEQNTERSFFLRMKCTLTSRGRTMNIKSATWKVLHCTGHIRVY
DTCNNQSQCGYKKPPMTCLVLICEPIPHPSNIEVPLDSKTFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMFTKGQVT
TGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYVVSGIVQHDLIFSLGQTECMLKPVEAVD------------------------------RKI
TELLTNVE-TEDTSSLFEKLKKEPDALTLLAPAAGDTIISLDFDNN--DE-QQLEVPLYNDVMLPSSSEKLQLAMSPLPATETTKPLRSNADPALNQPAS
PSDATRQSSP-PSSSSEYCFDVDNDMANEFKLELVEKLFAEDTEAKNPFSTQDT-DLDLEMLAPYIPMDDDFQLRSFDQLSPLENTSTLNASPYSVYINE
TASAPA-SPYDGNRSRTASPDRAKGPRSPVTLSYGTTALDEELNPKILALQNSQRKRK
>tr|G3SJ03|G3SJ03_GORGO Uncharacterized protein (Fragment) OS=Gorilla gorilla gorilla GN=HIF1A PE=4 SV=1
----DKSPCRISSERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASVMRLTISYLRVRKLLDAGDLDI--EDEMKAQMNCFYLKALDGFV
MVLTDDGDMIYISDNVNKYMGLTQFELTGHSVFDFTHPCDHEEMREMLTHRNGLKKGKEQNTQRSFFLRMKCTLTSRGRTMNIKSATWKVLHCTGHIHVY
DTNSNQPQCGYKKPPMTCLVLICEPIPHPSNIEIPLDSKTFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMFTKGQVT
TGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYVVSGIIQHDLIFSLQQTECVLKPVESSD------------------------------MKM
TQLFTKVE-SEDTSSLFDKLKKEPDALTLLAPAAGDTIISLDFGSND-DDQQLEEVPLYNDVMLPSPNEKLQLAMSPLPTAETPKPLRSSADPALNQTPS
PSDGTRQSSPE------YKFDSNTYLNH--KLHLCVCL---------NFSTLK----LLQELLPNLDLSTCFRLKNWSRLFPIAHSKLIDYRGWDIQSEQ
LFSCTCQSQSVTTHQVTLKPKKTKLLITRACIS---------IVP-TISLHCYIFSVK
>tr|V9KA26|V9KA26_CALMI Hypoxia-inducible factor 1 alpha OS=Callorhinchus milii PE=2 SV=1
----NPEKKRVSSERRKEKSRDAARCRRSKESEVFYELAHQLPLPHSVSSHLDKASIMRLTISYLRMRKLLSPRDVEV--EPDREKQLNSFYLKALEGFV
LVLTQDGDMIYMSENVNKYMGLTQFELIGHSIFDFTHPCDHEEMREMLSHRQGLKKGKDQITERSFFLRMKCTLTSRGRTVNIKSSSWKVLHCTGHIQVH
EGSDEQTPCGYKEPPMTCLALVCEPIPHPSNIEVPLDSKTFLSRHSLDMKFSYCDERITELMGYQPDELLGRSVYEYYHAMDSDHLTKTHHDLFSKGQAT
TCQYRMLSKEGGYVWVETQATVIYNTKNSQPQCIVCVNYVLSGVVEKGVVFSLDQTESVPVTDESPD------------------------------TIE
TTGKSYNS-PTESNDLFNKLKEEPEALTQLAPAAGDTIISLDFSPS--DS-EMQHFPLYNDVMLPSSTEQ-K--LSPLPPSDPTKSLCSTTDPALNLPNS
PSCPTNQSSP-PSSPSEYCYNVDTDMSNVFKLDIVEKLFAVDPEAKNPFSVQDVDGLDLEMLAPYIPMDDDFQLRSLDQLSPLTDIQAVNSSPSPLHMDE
VSSTPG-SPYSKPTSRTASPVRTGLSGSPKP--KRGGNLQEEVDAKLLSLHNLQRKRK
>tr|B7SCS8|B7SCS8_9CHON Hypoxia-inducible factor 1 alpha OS=Hemiscyllium ocellatum GN=HIF-1a PE=2 SV=1
----TEKKCSGSSERRKEKSRDAARFRRGKESEVFYELARELPLPHSVTSHLDKASIMRLTISYLRMRKLLNAGDMEV--EADLEEQLNSFYLKALEGFV
MVLTQDGDMIYMSENVNKCMGLTQFELIGHSVFDFTHPCDHEEMREMLSHRQGLKKGKDQNTERNFFLRMKCTLTSRGRTVNIKSATWKVLHCTGHIRVY
KSSNEQTHCGYKEPPMTCLILICEPIPHPSNIEVPLDSKTFLSRHSLDMKFSYCDERITELMGYQAEELLGRSVYEFYHALDSDHLTKTHHDLFTKGQAT
TGQYRMLGKEGGYVWVETQATVIYNSKNSQPQCIVCVNYVLSGLVEKEVILSLDQIECVPVE--KPE------------------------------EP-
--SKHPVS-STETNNLFDKLKEEPEALTQLAPAAGDTVVSLDFNPS--EMQQFNEVPLYNDVMLPSSTNQ-KMALSPLPPSDAKKPLCSSTDPALNLSSS
SSCPSSQNSP-PSSPSDYCFNVDTDISNEFKLDIVEKLFAIDPEAKHPFSVQDIDNLDLEMLAPYIPMDDDFQLRSLDQLSPFSDCQTVDPLSTP--TIK
RDNGPS-SSQNKKSNRTTSPVRTGLPQSSKA--KRGEAPKEELSPQLLILHNSPRKRK
>tr|B4Y034|B4Y034_MUSCA Hypoxia-inducible factor 1 alpha OS=Mustelus canis GN=HIF-1a PE=2 SV=1
----SEKKCGGSSERRKEKSRDAARCRRSKESEVFYELAYELPLPHSITSHLDKASIMRLTISYLRMRKLLDAGNAEI--EADVEKHLNSFYLKALEGFV
MVLTQDGDMIYMSENVNKCVGLTQFELIGHSVFDFTHPCDHEEMREMLSHRQGPKKGKDQNTERNFFLRMKCTLTSRGRTVNIKSATWKVLHCTGHIRVY
KSNNEQTHCGYKEPPMTCLVLICEPIPHPSNIEVPLDSKTFLSRHSLDMKFSYCDERITELMGYQPEELLGRSVYEFYHAMDSDHLTKTHHDLFTKGQAT
TGQYRMLGKEGGYVWVETQATVIYNSKNSQPQCIVCVNYVLSGLVEKEVVLSLDQTECAPVSDEKSE------------------------------EP-
--SKSPVS-STKADNLFDKLKEEPEALTQLAPAAGDTVVSLDFSPS--EMQPFKEVPLYNDVMLPSSTNQ-KMALSPLPPTDSKKALCNSTDPALNLPSS
SSCPTSQNSP-PSSPSDYCFNVDADISNEFKLDIVEKLFAIDPEAKHPFSVQDINDLDLEMLAPYIPMDDDFQLRSLDQTSPLADSQTVGSLSSL--TNQ
IVSTPG-SPQNEKSSRTASPVRTELPQSTES--ESREAPNEDLSPMVLLLHNSPRKRK
>tr|D6NF15|D6NF15_MEGAM Hypoxia-inducible factor 2 alpha OS=Megalobrama amblycephala GN=HIF-2alpha PE=2 SV=1
----EKEKKRCSSERRKEKSRDAARCRRSKETEVFYELAHQLPLPHSISSHLDKASIMRLAISFLRTRILLTSGYVAATETTDVDRLMDSWYLKSLGGFI
TVVTSDGDMIFLSENINKFMGLTQVELTGHSIFDFTHPCDHEEIRENLSLKAG-KKGKELNTERDFFMRMKCTVTNRGRTVNLKSASWKVLHCTGHLKVC
NGCPARVLCGYKEPPLTCVVMMCEPIPHPSNIDTPLDSKAFLSRHSMDMKSTYCDDRVTELMGYSPEDLLGRSAYDFYHALDSDNVTKSHQNLCTKGQAV
SGQYRMLAKNGGYVWVETQGTVIYNSRNSQPQCIVCVNYVLSDVEERSMIFSMDQTESLFKPHNLK---------------------------------S
F-FSPSKISLGPGEVLFTRLKEEPEELTQLAPTPGDTIISLDFGQ---QYEQH---PMLSKVS-------S-LAPPVSHSIHDGH---------SY-SSA
-----------PSSPGDYYTPVDS----DLKVELTEKLFSLDTQTKASCNQTDLSDLDLETLAPYIPMDGDFQLNIC-QEEPAS-IGGTSIPYSRGPQMP
PYHDPADTPLSSMGGRQNLQWPPG-RS--PANRQR--LNYRDMSPARLALASFKRS--
>tr|G4WI69|G4WI69_MYXAS Hypoxia-inducible factor 2a OS=Myxocyprinus asiaticus GN=HIF-2a PE=2 SV=1
----EKEKKRCCSERRKEKSRDAARCRRSKETEVFYELAHQLPLPQSISSHLDKASIMRLAISFLHTRKLLTSDCVTATETTEVDRLMDTWYVKSLGGFI
TVVTSDGDMIFLSENINKFMGLAQVELTGHSIFDFTHPCDHEEIRENLSFKTG-KKVKDLNTERDFFMRMKCTVTNRGRTVNLKSASWKVLHCTGQLKVY
NGCPAHVLCGFKEPPLTCVVMMCEPIPHPSNIDTPLDSKTFLSRHSMDMKFTYCDDRVTELMGYNPEDLLGRSAYEFYHALDSDSVTKSHQNLCTKGQAV
SGQYRMLAKHGGYVWVETQGTVIYNSRNSQPQCIVCVNYVLSDIEEKSIIFSLDQTESLLKPQHLS---------------------------------S
F-FSPSKGL--DSEELYNKLKEEPEDLTQLAPTPGDTFISLNFGR---QYEEH---PGYSEVS-------S-IAPSVSHTIHDGH---------NY-SSA
-----------PSSPEDYYNTVDT----DLKVELTEKLLSLDTQTKTSYNQTDLSDLDLETLAPYIPMDGDFQLNIC-QEEPSS-IGGTSVPYSNGPQIP
PYHDPASTPLSSMGGRQNLQWPPG-RS--PANQQR--QCYRETRPVQLALASFKRS--
>tr|W5KA07|W5KA07_ASTMX Uncharacterized protein OS=Astyanax mexicanus PE=4 SV=1
----EKDKRRSTSERRKEKSRDAARCRRSKETEVFYELAHQLPLPHSVRSHLDKASIMRLAISFLRTRKLLTSGCRPS--ETEMDRQMDSLYVKSLEGFV
SVVTSDGDIIFLSENINKFMGLTQVELTGHSIFDFTHPCDHDEIRENLSLKTG-KKGKELSTERDFFMRMKCTVTNRGRTVNLKSASWKVLHCTGHLKVY
NSCPPRVLCGFKEPPLTCVVMMCEPIPHPSNIDTPLDSKTFLSRHSMDMKFTYCDDRVTELMGYSPEDLLGHSVYEFYHALDSESCTKSHQNLCTKGQAV
SGQYRMLAKHGGYVWVETQGTVIYNSRNSQPQCIVCVNYVLSDIEEKNKILSINQTESSFKTHHMS---------------------------------S
F-FSQAGAAVATGGALFTKLKEEPEDLTHLAPTPGDAIIALDFAP----YKDY---PTCSKI-------------SATHSTDEGQ---------SF-SSA
-----------PSSPGDYYSSVDN----DLKVELTEKLFALDTQTKNSCSQTDLSDLDLETLAPYIPMDGDFQLNIC-PEDSPC-AAGANMVYG-SPQLP
PYHDPACTPLSSMGGRQNLQWPPG-RS--PVNRHRPGEAYRDMSPARLAIASMKRS--
>tr|G3TB90|G3TB90_LOXAF Uncharacterized protein OS=Loxodonta africana GN=HIF1A PE=4 SV=1
----ANDKKKISSERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASVMRLTISYLRVRKLLDAGDLDI--EDEMKAQMNCFYLKALDGFV
MVLTDDGDMIYISDNVNKYMGLTQFELTGHSVFDFTHPCDHEEMREMLTHRNGPKKGKEQNTQRSFFLRMKCTLTSRGRTMNIKSATWKVLHCTGHIHVY
DTNSNQSQCGYKKPPMTCLVLICEPIPHPSNIEVRIDSKTFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYDYYHALDSDHLTKTHHDMFTKGQVT
TGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYVVSGIIQHDLIFSLQQTECVLKPVESSD------------------------------MKM
TQLFTKVE-SEDTSSLFDKLKKEPDALTLLAPAAGDTIISLDFGSNDTDDQQLEEVPLYNDVMLPSSSEKLQLAMSPLPASETPKPLRSSADPALNQPAS
PSDGTRQSSPEPNSPSDYCFDVDSDMVNEFKLELVEKLFAEDTEAKNPFATQDT-DLDLEMLAPYIPMDDDFQLRSFDQLSPLESSSAITASPSPTHVPK
ETTSARTSPYNDTQSRTASPSRAKGPRSPVTLSQRTTVPEEELHPKIIALQNAQRKRK
>tr|E7FAJ1|E7FAJ1_DANRE Uncharacterized protein OS=Danio rerio GN=epas1a PE=4 SV=2
----EREKKRHPSERRKEKSRDAARCRRSKETEVFYELAHQLPLPHSISSHLDKASIMRLAISFLRTRKLFSSGHTVQQMRSQNLGQMDNLYLKSLEGFV
IVVTSDGDMIFLSENVSKFMGLTQVELTGHSIFDFTHPCDHEEIRENLSIKSVYRKGKEMSTSRDFFMRMKCTVTNRGRTVNLKSASWKVLHCTGHLQVC
SSRPPQILCGFSEPPLTCITMLCAPIPHPSNVDTPLDSKTFMSRHSMDMKFIYCDERVSSLIGYRPEELLGRSVYEFCHALDSENMTKSHQNLCNKGQVV
SGQYRMLAKNGGYVWVETQATVIYNNRNSQPQCIICINYILSSVEEQSVIFSLDQTEALFKPYHTYD------------------------------MGE
I-FSQNT--SIPQNNLFTTLKEEPEELAQLAPMPGDAIIALDFER---EFEEA---TFFSKSS-------KLPAVGPSWVVDTPP--------GSP-GKT
PC---------PNSPVDCCGSGEW----DLKVELTEKLFAPESGATNPTDSLNLSDLDLETLAPYIPMDGDFQLHIC-LEEPVP--GLAD----------
-------------KQRQSLHWPPVGPGQTV---QRPV--QKGMSLGQRALLNFKRKRQ
>tr|A0A0B5KUC0|A0A0B5KUC0_9TELE Hypoxia-inducible factor 2 alpha A OS=Platypharodon extremus PE=2 SV=1
----EKEKKRHPSERRKEKSRDAARYRRSKETEVFYELAQQLPVPHSVSSHLDKASIMRLAISYLRTRKLFNSGRTVLQTQSQDDSQMDSLFMKSLEGFV
AVVTSDGDMIFLSENVSKCMGLTQVELTGHSIFDFTHPCDHEEIRENLSVKSLYRRGKDMSTGRDFFMRMKCTVTNRGRTVNLKSASWKVLHCTGQLQVC
SSRPPQVLCGFSEPPLTCVTMLCAPIPHPSNVDTPLDSKTFMSRHSMDMKFIYCDERVSSLIGYSPEELLGRSVYEFCHALDSESMTKSHQNLCNKGQVV
SGQYRMLAKHGGYVWMETQATVIYNNRNSQPQCIICINYVLSSVEEQSVIFSLDQTESLFKPYHMCN------------------------------MGE
L-FSQGGASSVAEDILFTKLKEEPEELAQLAPMPGDAIIALDFDR---DFEEP---TFFSKSA-------QLPVVVPSWVVNTPP--------GSP-GKT
PC---------PSSPVDYSGSGEC----DLKVELTEKLFNSESVATNLTDSLDPSDLDLETLAPYIPMDGDFELHIC-PEEPVS--GLAD--TCPDTHVQ
PYQTAPNVPFSSREGRQILQWPPIRPGQAS---HRPV--QKLMSVGQIALVNFKRKRS
>tr|H2NLG0|H2NLG0_PONAB Uncharacterized protein OS=Pongo abelii GN=LOC100939432 PE=4 SV=2
----ANDKKKISSERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASVMRLTISYLRVRKLLDAGDLDI--EDEMKAQMNCFYLKALDGFV
MVLTDDGDMIYISDNVNKYMGLTQFELTGHSVFDFTHPCDHEEMREMLTHRNGPKKGKEQNTQRSFFLRMKCTLTSRGRTMNIKSATWKVLHCTGHIHVY
DTNSNQPQCGYKKPPMTCLVLICEPIPHPSNIEIPLDSKTFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMFTKGQVT
TGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYVVSIVIFHTITSSIEDENCNFKVENILM------------------------------YKK
VEEVSIVD-CKDNSDLCENPCGRAQWLTPVIPALWEAEAGGSLEVRNTDDQQLEEVPLYNDVMLPSPNEKLQLAMSPLPTAETPKPLRSSADPALNQPPS
PSDGTRQSSPEPNSPSEYCFYVDSDMVNEFKLELVEKLFAEDTEAKNPFSTQDT-DLDLEMLAPYIPMDDDFQLRSFDQLSPLESSSAVTASPSPTHIHK
ETTSATSSPYRDTQSRTASPNRAKGPRSPVALSQRTTVPEEELNPKILALQNAQRKRK
>tr|T1Q070|T1Q070_ACISI Hypoxia-inducible factor 2 alpha subunit OS=Acipenser sinensis PE=2 SV=1
----DKEKKRSSSERRKEKSRDAARCRRSKETEVFYELSHQLPLPHNVSSHLDKASIMRLAISFLRTRKLVSSIWPDNES--ESDKQMDGLYLKALEGFI
AVVTQDGDMIFLSENINKIMGLTQVELTGHSIFDFTHPCDHDEMRENLSLRNGFKKNKDLNTERDFFMRMKCTVTNRGRTVNLKSASWKVLHCTGQVKVY
NSCPPHTLCGFKEPPLTCVVMMCEPIPHPSNIDMPLDSKTFLSRHSMDMKFTYCDERVTELMGYWPEELLGRSVYEFYHALDSDRMTKSHQNLCTKGQAV
SSQYRMLAKHGGYVWVETQGTVIYNTRNSHPQCIVCVNFVLSDIEENSVIFSLDQTESLLKPHVLSM------------------------------NSF
F--NS--GVPAASEQLFTRLKEEPEELAQLAPTPGDTIISLDFG-----GPPFEEAPLYK-AVM--------PPPNKPWAVEERNPCSQ--------ARL
STSSSTP-----SSPGDYYSSLDN----DLKVELTEKLFAMDTAAKAQCTTLELNDLDLETLAPYIPMDGDFQLNIC-QEEPPLSNSDASLP----TLVP
FYHTPTSTPLSSMGGRQNVQWPPKW------HSQ-E-QGKD-VTPARTAVAHYKRKRQ
>tr|V9KF35|V9KF35_CALMI Hypoxia-inducible factor 2 alpha OS=Callorhinchus milii PE=2 SV=1
----DKEKKRSNSERRKEKSRDAARCRRSKETEVFYELAHQLPLPHNVSSHLDKASIMRLTISFLRTRKLLTSGLEN---ETDSERQMDSLYLKALEGFI
TVVTQDGDIIFLSENVNKHMGIAQVELTGHSIFDFTHPCDHEEIRENLTLKNGFKKNKDLNTERDFFMRMKCTVTNRGRTVNLKSATWKVLHCTGHIKMY
NTCLPHTLCGYKEPPLTCLIMMCEPIQHPSNIDVPLDSKTFLSRHSMDMKFTYCDERVTTLMGYHPEELLGRSVYEFYHALDSDHMTKSHQNLCTKGQAV
TGQYRMLAKHGGYVWVETQGTVIYNSRNSQPQCIVCVNYVLSDVEEKNVMFSMDQTESLFKPCLPLR------------------------------N-V
N-GRYINGASVDSELLFSKLKEEPEELAQLAPTAGDAIISLDFGING-QLEKT---SLYNKGA-------M-PPPNKQWPVEITK----VNGPAEL-NAT
PS---------PSSPGDYYSSMDN----DLKIELTEKLFSMDTQAKNQCSQVELSDLDLETLAPYIPMDGDFQLSIC-CEEPPT-NT-NS-----HIPLP
QYHGSVNTPVSSMGGRPSIQWPPKWFFGTPAQRVK--QHGKDISPALTAFTNLKRKRQ
>tr|T1Q050|T1Q050_POLSE Hypoxia-inducible factor 2 alpha subunit OS=Polypterus senegalus PE=2 SV=1
----DKEKKRNSSERRKEKSRDAARCRRSKETEVLYELAHQLPLPHSISSHIDKASIMRLTISFLRTRKLLSSTIPSS--DSGSDKYIDSLYLKTLDGFI
AVVTQDGDMIFLSENINKFMGLTQVELTGHSIFDFTHPCDHEEIRENLSPKHGFKKNREASSVRDFFMRMKCTVTNRGRTVNLKSASWKVLHCTGHLKMY
NSHHPHTLCGFKEPPLNCVIMICEPIPHPINIDIPLDSKTYLSRHSMDMKFTYCDERITELMGYSPEELLGRSIYDFYHALDSDSLTKSHHNLCTKGQAV
SGQYRMLAKHGGYVWIETQGTVIYNSRNSQPQCIVCINYVLSEIEEDSIIFSMDQTESLFKPHVIS---------------------------------M
S-NFFSSGMPTSSELLFTKLKEEPEELAQLAPTPGDAIISLDFGA---PFDEP---PIFNQKA-------I-HPPKKPWPQVENI---------SS-SCT
PS---------PSSPGDYYSTMDS----ELKVELTEKLFAMDTESKSQCKTPELSDLDLETLAPYIPMDGDFQLNIC-QEEHPL-KPPTSLSYA-GSVAP
PYLTPSSTPLSSMGGRQNIQWPPKWTA--PHHQQR--HQNKEMIAVQQDFISFKRKRH
>tr|W5NHS9|W5NHS9_LEPOC Uncharacterized protein OS=Lepisosteus oculatus PE=4 SV=1
----EKEKKRSSSERRKEKSRDAARCRRSKETEVFYELAHQLPLPHNVSSHLDKASIMRLTISFLRTRKLLSSTWPDNVS--EADRQMDSLYLKALDGFI
AVVTQDGDMIFLSENINKFLGLTQVELTGHSIFDFTHPCDHDEIRENLSFKPGFKKNKDLNTERDFFMRMKCTVTSRGRTVNLKSASWKVLHCTGHLKVY
NSCPPHVLCGFKEPPLTCVIMMCVPIPHPSNIDMPLDSKTFLSRHSMDMKFTYCDDRVTELMGYCPEDLLGRSVYEFYHALDSDSMTKSHQNLCTKGQAI
SGQYRMLAKHGGYVWVESQGTVIYNSRNSQPQCIVCVNYVLSEIEESLVLFSMDQTESLFKPHVLSM------------------------------GSF
F--SN--GAAASSELLFTKLKEEPEDLAQLAPTPGDAIIALDFG-----GPQYEEAQMYSKAAM--------APPSKTWPVEAQQPSVQ--------GSS
TTSSSTP-----SSPGDYYSPMDN----ELKVELTERLFALDTDPKSPYTTSEVSDLDLETLAPYIPMDGDFQLNIC-QDEVPLPSS-ANLP----TVMP
PYHTPSSTPLSSMGGRQNLQWPPKR------YRQ-Q-PQKD-MSPSRIALVSFKRKRL
>tr|D7NII2|D7NII2_9CHON Hypoxia-inducible factor 2 alpha (Fragment) OS=Hemiscyllium ocellatum GN=HIF-2a PE=2 SV=1
---------------------------------------------LIVSTHLDKASIMRLTISFLRTRKLLSSGGPE-T-ETETEKQMDALYLKALEGFI
MMATQDGDIIFLSENISKYMGLTQVELTGHSIFDFTHPCDHEEIRENLTIKN-FKKHRDMNTERDFFMRMKCTVTNRGRTVNLKSATWKVLHCTGHIKIY
NACQAHTLCGYKEPPLTCLIMMCEPIQHPSNIDIPLDSKTFLSRHSMDMKFTYCDERIAALMGYCPEELLGRSVYEFYHALDSDHMIKSHQNLCTKGQSV
TGQYRMLAKHGGYVWVETQGTVIYNSRNSQPQCIVCVNYVLSEIEEKNVVFSMDQTESLFKPCQAMK------------------------------NMN
G--KHICGGPMDGNLLFSKLKEEPEELAQLAPTPGDSIILLDFSV---GNQQFEEAPLYNKA-I--------IPQNKLWPMEATKPNMK--------GNC
SSTS-------PSSPGDYYSSLDN----DLKIELIEKLFALDTEAKKQCSTAELSDLDLETLAPYIPMDGDFQLSIC-HDEQPPSNTPSNLSGN--RSLA
AYHAPGCTPASLMGGRPNVQWPPKWLP----GHQ-Q-HGKDITNE--MIFRNLKRKRQ
>tr|T1Q053|T1Q053_PROAN Hypoxia-inducible factor 2 alpha subunit (Fragment) OS=Protopterus annectens PE=2 SV=1
----DKEKKRTSSERRKEKSRDAARCRRSKETEVFYELARQLPLPHSISTHLDKASIMRLTISFLRTRKLLSSAWP--K-ETESDCQMDGLYLKALEGFI
TVVTQDGDMIFLSENVSKYMGLTQVELTGHSIFDFTHPCDHEEIKENLCLKN-YKKNREMNSERDFFMRMKCTVTSRGRTVNLKSATWKVLHCTGHIQTH
GSCQQHTLCGFKDPLLAYLIIVCAPIQHPSNIDIPLDSKTFLSRHSMDMKFTYCDDRITELMGYHSEELLGRSVYEFYHALDSENMTKTHQNLCTKGQVI
SGQYRMLAKHGGYVWIETHGTVIYNSRNSQPQCIICINYVLSTIEENNTVFSVDQTESVFKPHLMTM------------------------------NSI
F--SR--SVLAQGDLLYRKLKEEPDDLEQLAPTPGDAVVSLDF-----GTQRFDDSSVYKKSIM--------PLTNTSWTPEAKKPSSE--------GSC
SSSSSTP-----SSPGDYYGPLES----DLKTELVEKLFAMDTESKNQCNTADFNELDLETLAPYIPMDGDFQLNIC-QEEHPVSYPQSGLAD---KGLP
PYQAPASTPLSSQGGRANVQWPPKWFS--TQQSQ-Q-RGKD-VTPAMIAISSLKRKRQ
>tr|F7F7N2|F7F7N2_MONDO Uncharacterized protein OS=Monodelphis domestica GN=EPAS1 PE=4 SV=1
----DKEKKRSSSERRKEKSRDAARCRRSKETEVFYELAHELPLPHNVSSQLDKASIMRLAISFLRTHKLLSSVCTENETEVETDQQMDNLYLKALEGFI
AVVTQDGDMIFLSENINKFMGLTQVELTGHSIFDFTHPCDHEEIRENLSLKSGFKKSKDMSTERDFFMRMKCTVTNRGRTVNLKSATWKVLHCTGQVKVY
NSCAPHSLCGYKEPLLTCLIVMCEPIQHPSTMDIPLDSKTFLSRHSMDMKFTYCDDRITELIGYHPEELLGRSAYEFYHALDSESMTKSHQNLCTKGQVI
SGQYRMLAKHGGYVWLETQGTVIYNTRNLQPQCIICVNYVLSEIEKNDVVFSMDQTESLFKPHLMAM------------------------------NNI
F--DT--EIPVKSNFLFAKLKEEPEELAQLAPTPGDAIISLDFG-----NQSFEESSTYNKA-L--------LTPSQPWPGDMKNHSCQ--------GST
SN---------PSSPGDYYSSLDE----NLKMEMIEKLFAMDTESKNQCNTTDFNELDLETLAPYIPMDGDFQLSIC-QEERPQLNTQSSIFGS--KTLP
PCYGPASTPLSSMGGRSNTQWPPKW---KSPPNK-P-RGPDKMNPAVIALSKLKMKRQ
>tr|Q6GP97|Q6GP97_XENLA MGC80589 protein OS=Xenopus laevis GN=epas1 PE=2 SV=1
----EKEKKRNSSERRKEKSRDAARCRRSKETEVFYELAHQLPLPQSISSHLDKASIMRLAISFLRTHKLLSSVCADRNIETDSEKQMDNLYLKALEGFV
AVVTQDGDMIFMSENVNKYLGLTQVELTGHSIFDFTHPCDHDEIRENLSMKTGSKKNRDANTEHDFFMRMKCTVTNRGRTVNLKSATWKVLHCTGHVKAY
NSYHPHSLCGFKEPILSCLIMMCQPIQHPSNIDIPLDSKTFLSRHSMDMKFTYCDDRIIELIGYHPEELLGRSAYEFYHALDSENMTKSHQNLCAKGQVV
TGHYRMLAKHGGYLWVETQGTVIYNTRNSQPQCIVCVNYVLSEIEKNDVVFSMDQTESLFKPHFLTM------------------------------NSI
F--SS--S--VKSDFLFTKLKEEPEELAQLAPTPGDEIVSLDF-----GSQTFDEPASFNSSVQ--------TSPSKPWPLEVKNLNSQ--------GNS
SNSTSTP-----SSPEAYYSSLDE----DLKIELIEKLFAMDTEAKNQCNTNDFNDLDLETLAPYIPMDGDFQLNIC-QEESTINTPQCSVLEK-MAPLT
PYHTGATPPLSSMGGRPNVQWPPKWLT--LPHNQ-Q-RGKD-LHPTEIPFCSVKRKRP
>tr|H3BEE1|H3BEE1_LATCH Uncharacterized protein OS=Latimeria chalumnae PE=4 SV=1
----FVTPHRVCSEKRREKSRDAARCRRGKESEMFFHLAQQLPAPYSITSRLDKASIMRLTISYLRLRHLLSALTLKGEKEASGFPEETDLVFTALKGFL
MVVSQTGEMIFLSDNATGFLGPTQVELVGQNLFDFIHPCDQEEIRNVLSLKH--ISRKKQSKDCDFFVRMKCTLTNQGRMVNLKSASWKVLHCTGQVKLT
PSHQ--------GAPQGCLVLLCEPIPFPSELETPVSKEMFLTRHSLDMKFTYCDKRVKDLIGYQESELLGRSVYEYYHVLDADRIRKSHHNLFAKGQTS
TGQYRMLCKHGGYVWVQTDASVIYSDRNSQPRCVICINYVLSRSLETEIIVSLEQTERLFKSWDVLH------------------------------TDS
--------MLPESRLPFRKLRESPEELVQLSPSPGDVVKSFDFTAQG---TCPVAMVIYP-----P-------PSSQATPLLTPNT---NTPPL---TRT
PST--------PNTRRQHYNPRKN----TFEVELIEKLFASDLDSQTRCSPGDFNDLDLETLAPYIPMDGDFELTIC-QEHPSPS---MSPSCC------
--YGEARTCMHYGGIQQRILWPP--TAPP----RRPPFHFTGRSVSALIFLSLKRKQE
>tr|S4RYA8|S4RYA8_PETMA Uncharacterized protein (Fragment) OS=Petromyzon marinus PE=4 SV=1
----EEKNNNATSERRKEKSRNAARCRRSKETEVFCELARELPLPQSVSASLDKASVMRFAISFLRMRKLLASDGSTE--HIDSMGDIDPAFLKVLEGFF
LVMNHDGDIVYLSDNVSKYLGTTHVDLVGQSIFDFTHPCDHEEIKEILSCKQGSKKNKETPTEIDFLMRMKCTITNRGRTVNLKSASWKVLNCSGHQKVC
GSSSTESSHGFKDPAQTYLVLICQPIPHPAELEAPLDSHTFLSRHTLDMKFSYCDDRVVDLIGYCPEELLGKSVYEYYHALDSDNITKSHHSLFSKGQAK
TGQYRMLAKHGGYVWVQTQASVIYNSRSAQPQSVVCIHYVLSGVEENTTIFSLEQTERLFKLQDTAQ------------------------------GAE
GDEACPREAPQDSGRLYAMLKEEPDELAQLAPTPGDTIVPLQFNS---VFIYT-----YKNYNSAP----LC--------DDTT---RCRTGKQAP-TST
PS---------PGSPEDVYASC-N----DLRVELVEKLFAKSTD--QNSYTDDYSTVDLEMVAPYIPMDGDFQLCLS-LQEQMAANPLSS-VTKPAINDS
SFYGATDQGLA-AAGKCGSSWPYGRKR--VAAQQRPCKRSPE---------NLKRKWH
>tr|A0A0F7ZE51|A0A0F7ZE51_CROAD Endothelial PAS domain-containing protein 1-like OS=Crotalus adamanteus PE=2 SV=1
----EKEKKRSSSERRKEKSRDAARCRRSKETEVFYELAHELPLPHNISSHLDKASIMRLAISFLRTHKLLSSVCSHNEREIETDQQLDNLYLKALEGFI
TVITQDGDMIFLSENISKYMGLTQVELTGHSIFDFTHPCDHEEIRENLSLKNGCKKNKEMSLERDFFMRMKCTVTNRGRTVNLKSATWKVLHCTGQIKVY
NTCPPHALCGFKEPLLSCLILMCEPIQHPSNTDIPLDSKTFLSRHSMDMKFTYCDDRITELVGYHPEELLGRSAYEFYHALDSENMTKSHQNLCGKGQVV
TGQYRMLAKHGGYVWLETQGTVIYNTRNLQPQCIICVNYVLSEIENNEIVFSMDQTESLFKPHMMSM------------------------------NSI
Y--DH--GIPVKSDFLFTKLKEEPEELAQLAPTPGDAIISLDF-----GTQKFEEIPTYNKA-A--------MTPNTQWVTEGKNQGSQ--------GSS
SNSSSTP-----SSPGDYYTSLDE----DLKIEMIEKLFAMDTDAKNQCSSSDFNELDLETLAPYIPMDGDFQLSIC-QEERPLCSVQNSAFGSQSSFLL
PYYAQANTPLSSMGGRPNTQWPPKWN---SAPNK-Q-RGID-INPARIALASLKLKRQ
>tr|Q8QGM4|Q8QGM4_FUNHE Hypoxia-inducible factor 2 alpha OS=Fundulus heteroclitus PE=2 SV=1
----DKEKKRSSSERRKEKSRDAARCRRSKETEVFYELAHQLPMPHSVSAHLDKASIMRLAISFLRTRKLIATSSGSGSCNGAEDELMDNMYLKSLEGFI
TVVTSDGDMIFLSENINKFMGLTQVELTGHSIFDFTHPCDHEEIRENLSLKSSFKKGKDVSTERDFFMRMKCTVTNRGRTVNLKSASWKVLHCTGHLKMY
DGCPSRVLCGYKEPPLTCAVLMCEPIQHPSNIEAPLDSRTFLSRHNMDMKFTYCDDKVTELIGYSPEDLMGRSIYEFYHALDSDSVTKSHHNLCTKGQAV
SGQYRMLAKNGGYVWVETQGTVIYNSRNSQPQCIVCINYVLSDVEEKSVIFSLEQTEALFKTPHMS---------------------------------R
F-FTAEGAGRTPGDSLFTTFKEEPDELAQLAPTPGDTIISLDFGH---ELEKSQHPAPFTPVSSAS----MHPSGPPSWTSESRK----AQTPASA-GSA
-----------PSSPGDYYSSVES----DQRLELTEKLFALETENDSDAHTEDLSDLDLETLAPYIPMDGDFQLNII-PESEPL-MS-AS-SCMMGPQSP
HFRGPASTPLSS------MQWPPKAERPSIS--QR--QAYKDVNPARV---SIKRS--
>tr|S4R4L9|S4R4L9_PETMA Uncharacterized protein OS=Petromyzon marinus PE=4 SV=1
----LSLPSRVNSERRKEKSRDAARCRRSNETEVFYELANELPLPHSVTSHLDKASIMRLAISYLRMRKLLHNGAVV----EDCQEEMDSLFGKALEGFV
MALTEEGDMVFLSDGVNKCVGLAQVDLMGHSIFDFVHPCDQEEVREMLVYRQ---SVKAPPSEVCQXMRMKCTLTNRGRTVNLKSASWKVLHCSGHMKLY
EGSAASAGGKRARXQVLLLMKSRTPPARRANQQSALDFQTFQNPHVKFMVHACCTEEILMLFENLPEELHFSATPTTGHTAHAHPLVCSSHAVFTKGQAV
TGQYRILAKGGGYAWVETQATVIYSSRNSQPQCVVCVNYVLSGIVENDTIFSLEQTERLFKPNKAAV------------------------------GQV
-----SEGTDEDMALLYTQLKNEPDELAQLAPTAGDVVVPLDFGTG---LASFDDVPLYNDVMMAASPEPMPSPATPTKAFAELPAAVV--------QHG
PSSP-------PNSPSDYYS----AVGGDLKVDLIEKLFAVDSEIKEVSRVKSLDDMDLEMLAPYIPMDGDYQLCLSLPDGPLP----SS-------LPP
AAPQPP-----------------SR----------MPAEDAEIYLLSIIYNANNKN--
>tr|M3ZS27|M3ZS27_XIPMA Uncharacterized protein OS=Xiphophorus maculatus PE=4 SV=1
---------------------------------------------------------MRLAISFLRTRKLLTTS----HCDGEEDRLMDNLYLKSLEGFV
TVVTSDGDMIFLSENINKFMGLTQVELTGHSIFDFTHPCDHEEIRENLSLKSSFKKGKDQSTERDFFMRMKCTVTNRGRTVNLKSASWKVLHCTGQLKMY
DGCPSRVLCSYKEPPLTCAILMCEPIPHPSNIDVPLDSRTFLSRHSMDMKFTYCDEKVTELMGYTPEDLLGRSVYEFYHALDSDSVTKSHHNLCSKGQAV
SGQYRMLAKNGGYIWVETQGTVIYNSRNSQPQCIVCINYVLSDVEEKSVIFSLEQTEALFKSPNMS---------------------------------S
F-FTTEGASMNSGASLYKKFKTEPEDLAQLAPTPGDTIISLDFDR---EFEESQQPAPFTPVSSSP----MPPPGPACWTIESQHALDCAQTLAPA-GSA
-----------PSSPGDYYSSVES----DLRVELTEKLFALETENDSTAHTEDLSDLDLETLAPYIPMDGDFQLNII-PESEPQ-LS-AS-SYMMPPRNP
PFRGLAGTPLSS------MQWPPKAEQPSTS--QR--QAYKDLDPARV---SIKRS--
>tr|Q9XTA4|Q9XTA4_BOVIN Endothelial PAS domain protein 1/hypoxia-inducible factor-2 alpha OS=Bos taurus GN=EPAS1/HIF2 alpha PE=2 SV=1
----DKEKKRSSSERRKEKSRDAARCRRSKETEVFYELAHELPLPHSVSSHLDKASIMRLAISFLRTHKLLSSVCSENESEADADQQMDNLYLKALEGFI
AVVTQDGDMIFLSENISKFMGLTQVELTGHSIFDFTHPCDHEEIRENLSLKNGFKKSKDMSTERDFFMRMKCTVTNRGRTVNLKSATWKVLHCTGQVKVY
NNCPPHSLCGCKEPLLSCLIIMCEPIQHPSHMDIPLDSKTFLSRHSMDMKFTYCDDRITELVGYHPEELLGRSAYEFYHALDSENMTKSHQNLCTKGQVV
SGQYRMLAKHGGYVWLETQGTVIYNPRNLQPQCIMCVNYVLSEIEKNDVVFSMDQTESLFKPHLLTM------------------------------NSI
F--DNSGKVAVKSNFLFTKLKEEPEELAQLAPTAGDTIISLDFG-----TPNFEESSAYGKG-I--------LPPGQQWTGEVKSHGTH--------GNS
S--S-------PSSPGDYYTSLDD----NLKIEAIEKLFAMDTEAKDQCGTTDFNELDLETLAPYIPMDGDFQLSIC-PEESLLPTPQSNAFGS--RSLL
QCCGQTYTPLSSMGGISNTQWPPKW---EAPPHK-P-QGPDVMSPAMIALSKLKLKRQ
>tr|H2SMF4|H2SMF4_TAKRU Uncharacterized protein (Fragment) OS=Takifugu rubripes GN=LOC101067536 PE=4 SV=1
----RLSLCRTSSERRKEKSRDAARCRRSKETEVFYDLAHQLPLPHSVSAHLDKASIMRLAISFLRTRKLLDTSCSS-GSNCDEDKEMDSLYLKSLEGFV
AVVTSDGDMIYLSENINKFMGLTQVDLTGHSIFDFTHPCDHEEIRENLSLKTAYKKGKELSSERDFFMRMKCTVTTRGRTVNLKSAGWKVLHCTGQLKMY
NSCPPRGLCSFREPPLTCAVLMCEPIPHPSNIDTPMDTRTFLSRHSMDMKFTYCDERVTELMGYTPEDLLGRSVYDFYHALDSDKVTKSHQNLCTKGQAV
TAQYRMLAKNGGFIWVETQGTVIYNSRNSQPQCIVCINYVLSDIEEKSTIFSLEQIEALFKPRHMS---------------------------------G
F-LTEGGVGVVPGDALFTKLKEEPEDLTQLAPTPGDTIITLDFAR---QFEETRQAPGYG----------MALPDVPSWSNESLK----AKGPLPL-GSA
-----------PSSPGDYYSSVDS----DLKVELTEKLLILDTEDNGPANTMDLSDLDLETLAPYIPMDGDFELNIE-PLE----NSNAS-SCMMAHQNP
PYRAPARTPLSSMGGRQNLQWPPKSERLSIP--QS--TGVTSVLWPNVSNILLRSD--
>tr|M4XYS7|M4XYS7_SEBSC Hypoxia-inducible factor-2 OS=Sebastes schlegelii GN=HIF-2 PE=2 SV=2
----EKEKKRSSSERRKEKSRDAARCRRSKETEVFYELANQLPLPHSVSSHLDKASIMRLAISFLRTRKVVTTGC---SVDGDEDGQMDSLYLKSLEGFV
TVVTSDGDMIFLSENINKFMGLTQVDLTGHSIFDFTHPCDHEEIRENLSLKTGFKKGKELSTERDFFMRMKCTVTNRGRTVNLKSASWKVLHCTGTLKTY
SSCPPRVLCGFKEPPLTCAVLMCEPITHPSNIDTPLDSRTFLSRHSMDMKFTYCDDRVSELMGYSPEDLLGRSVYDFYHALDSDGVTKSHHNLCSKGQAV
SGKYRMLAKNGGYVWVETQGTVIYNSRNSQPQCIVCINYVLSDIEEKSMIFSLKQTESVFKPHHMN---------------------------------N
F-FSAGGAGVTPGDALFTKLKEEPEELAQLAPTPGDTIITLDFDR---QFEEPQQPAGYTTVSAAA----MPPPGPPSWASESHKP----APPASG-GSA
-----------PSSPGDYYSSVDS----DLKVELTEKLFALDTEKDSPENTRDLSDLDLETLAPYIPMDGDFQLNII-PESEPL-S--AS-SYILGHQSP
PYQAPASTPLSSMGGRQNLQWPPKTERPSAT--QR--QAYRDMSPARV---SIKRS--
>tr|F1M8I5|F1M8I5_RAT Endothelial PAS domain-containing protein 1 OS=Rattus norvegicus GN=Epas1 PE=4 SV=3
----DEEKHESSSELRKEKSRDAARCRRSKETEVFYELAHELPLPHSVSSHLDKASIMRLAISFLRTHKLLSSVCSENESEAEADQQMDNLYLKALEGFI
AVVTQDGDMIFLSENISKFMGLTQVELTGHSIFDFTHPCDHEEIRENLTLKTGFKKNKDMSTERDFFMRMKCTVTNRGRTVNLKSATWKVLHCTGQVRVY
NNCPPHSLCGYKEPLLSCLIIMCEPIQHPSHMDIPLDSKTFLSRHSMDMKFTYCDDRILELVGYHPEELLGRSAYEFYHALDSENMTKSHQNLCTKGQVV
SGQYRMLAKHGGYVWLETQGTVVYNPRNLQPQCIMCVNYVLVGIEKNDVVFSMDQTESLFKPHLMAM------------------------------NSI
F--DSSDDVALKSNYLFTKLKEEPEDLAQLAPTPGDAIISLDFG-----GQNFDESSTYGKA-I--------LPPGQPWATELRSHSAQ--------GNT
S--S-------PSSPEDYYSSLEN----HLKIEVIEKLFAMDTEAKDQCSTTDFNELDLETLAPYIPMDGDFQLSIC-PEEPLVPSPQSSIFGS--KSLP
PCCGQASTPLSSMGGRSNTQWPPKWLGPLSQPHM-A-RGPYMMSPAMIALSKLKLKRQ
>tr|Q9W7C6|Q9W7C6_CHICK Endothelial PAS domain protein 1 OS=Gallus gallus GN=EPAS1 PE=2 SV=1
----DKEKKRSSSERRKEKSRDAARCRRSKETEVFYELAHELPLPHNVSSHLDKASIMRLAISFLRTHKLLSSVCADNENELEADQQMDNLYLKALEGFI
AVVTQDGDMIFLSENVNKYMGLTQVELTGHSIFDFTHPCDHEEIRENLSLKNGFKKNKEMSTERDFFMRMKCTVTNRGRTVNLKSATWKVLHCTGQVKVY
NTCPPHTLCGYKEPLLTCLIIMCEPIQHPSNIDIPLDSKTFMSRHSMDMKFTYCDDRITELIGYHPEELLGRSAYEFYHALDSENMTKSHQNLCTKGQVV
TGQYRMLAKHGGYVWLETQGTVIYNTRNLQPQCIICVNYVLSEIEKNDIVFSMDQTESLFKPHLLTM------------------------------SSA
F--EN--GISGKSDLLFTKLKEEPEELAQLAPTPGDAIISLDFEL---GIQKFEEAPAYTSA-V--------LTPNKPWPVEVKSHAAQ--------GSS
SNSSSTP----N-SPEDYYTSVDD----DLKIEVIEKLFAMDTESKSQCNSTDFNELDLETLAPYIPMDGDFQLSIC-QEERTLSSAQSTVFMS-RSSLP
PYHNQASTPLSSMGGRPNTQWPPKWLS--SPPNK-Q-RGID-INPARIALSSLKLKRQ
>tr|K7G1Q3|K7G1Q3_PELSI Uncharacterized protein OS=Pelodiscus sinensis GN=EPAS1 PE=4 SV=1
----DKEKKRSSSERRKEKSRDAARCRRSKETEVFYELAHELPLPHNVSSHLDKASIMRLAISFLRTHKLLSSVCVDNESDLDIDQQIDNLYLKALEGFI
AVVTQDGDMIFLSENINKYMGLTQVELTGHSIFDFTHPCDHEEIRENLSLKTGFKKNKEMSTDRDFFMRMKCTVTNRGRTVNLKSATWKVLHCTGQVKVY
NSCPSHSLCGYKEPLLTCLIIMCEPIQHPSNMDIPLDSKTFLSRHSMDMKFTYCDDRITELIGYHPEELLGRSAYEFYHALDSENMTKSHQNLCAKGQIV
TGQYRMLAKHGGYVWLETQGTVIYNTRNLQPQCIVCVNYVLSEIEKNDIVFSMDQTESLFKPHLLTM------------------------------NTI
F--DN--GVPVKSDFLFTKLKEEPEELAQLAPTPGDAIISLDFAQ---GTQKFEEASIYNKAAV--------LTLNKQWPGEVKSHTSQ--------GSS
SNSSST-----PSSPGDCYSSLDE----DLKIEMIEKLFAMDTESKNQCNSTDFNELDLETLAPYIPMDGDFQLSIC-QEERPLPNAPSAVFSNSKSSLP
PYHVRGSTPLASMVGRPGTQWPPKWLA--SSPNK-Q-HGID-INPARTALASLKLKRQ
>tr|S7P9R1|S7P9R1_MYOBR Endothelial PAS domain-containing protein 1 OS=Myotis brandtii GN=D623_10033461 PE=4 SV=1
----RAPCKGSSSERRKEKSRDAARCRRSKETEVFYELAHELPLPHSVSSHLDKASIMRLAISFLRTHKLLSSVCSENESEAEADQQMDNLYLKALEGFI
AVVTQDGDMIFLSENISKFMGLTQVELTGHSIFDFTHPCDHEEIRENLSIKDGFKKSKDMSTERDFFMRMKCTVTNRGRTVNLKSATWKVLHCTGQVKVY
NNCPPHGLCGYKEPLLSCLIIMCEPIQHPSHMDIPLDSKTFLSRHSMDMKFTYCDDKITELIGYHPEELLGRSAYEFYHALDSENMTKSHQNLCTKGQVV
SGQYRMLAKHGGYVWLETQGTVIYNPRNLQPQCIMCVNYVLSEIEKNDVVFSMDQTESLFKPHLMAM------------------------------NSI
F--ENSDEVAVKSHFLFTKLKEEPEELAQLAPTAGDAIISLDFG-----NQSFEESSAYGET-I--------LAPNQSWAEELRSHIAQ--------GDT
---S-------PGSPEDYYTSLND----DLKMEVIEKLFAMDTEAKDQCSTLDFNELDLETLAPYIPMDGDFQLSIC-SEEKLSPNPQTSIFGS--KSLP
SCCGQASTPLSSLGGIFNTQWPPKW---ESPPQK-P-QGPDAMSPAMVALSKLKLKRQ
>tr|L7MG71|L7MG71_9ACAR Putative hypoxia-inducible factor 1 alpha subunit basic helix-loop-helix transcription factor b (Fragment) OS=Rhipicephalus pul
----APKERRKNSEKRKEKSRDAARCRRSKESEIFTELSQQLPLPESVACQLDKASVMRLAISYLRLREILEPIAEVA--KSAACSPYDSSVLEALDAVL
LVLSAEGEIVFLSDNVGRHLGLNQVDLMGQSVYEYCHPCDHDELKAALLPKP--DLHDLSPQPCHFLMRLRCTLGSKGRGVSVKSASYKMMQCVGTRVSR
EVAPPEEEQPKEEERRHFLVCVAQPIPHPSNIEAPLGTHTFLSRHNPSMCFTHVDDRTETFLGYSSEELLGKSVYSYFDPRDVLNLQQDFKTLFAKGQCE
TGQYRFLAKHGGCVWVLTQATLIYENSCSKPQCVVCVNYVLSGASGKHEVLAEQQLTSTAVKPKEPE------------------------------PKL
Q-FLIFA----DTGFTAVLRDDEPEDLTHLAPRAGDDTIPLEGLPSD-DAFSL--SDIYGDEN-------KLLPDYALLPPEEDCPLG-RKDPFLS-GST
PPSS-------------SCSDVPSE-------SPVDRFAGLELKPE----GTDLQDDDFDMRAPYISMNGDFPLL-PDPQDSSP--GSPT----------
--------PKSSLAALLVAELPPEWPRSTPHHPQSGLSAASDGRPHAYV--TTALEQK
>tr|V5HIH3|V5HIH3_IXORI Putative hypoxia-inducible factor 1 (Fragment) OS=Ixodes ricinus PE=2 SV=1
--------RRKNSEKRKEKSRDAARCRRSKESEIFSELSQQLPLAEGVTSQLDKASVMRLAISYLRMHEILEPIVELK--EKKVSSAYDASVLEALDGFL
VVLSADGDVLFLSENISRHLGLNQVDLMGQSLFEFCHPCDHDELKEVLCPGGKAETGEKFPQPCSFFVRLRCALGSKGRGVGVKSASYKVLHCVGHRVLR
DVAPREDDPEEEEEQRRFVVCVAQPIPHPSNIEVPLGSRTFLSRHSPSMRFTHVDDRIEKFLGYTSDELLGKSVYSYFDARDISALQKDFKTLFSKGQCE
TGQYRFLSKHGGYVWVLTQATLIYENSCSRPQCVVCVNYVLSGTSQEHEVVSEDQVIKAAAAPEPSE-------------------------------KR
P-FLMFA----DSGLTVLKEDSDPEDLTHLAPQAGDDSIPLEELPSD-DTFVL--SDPYGDNS-------KLLPDYALLPPEEDCPLG-HRDPFLN-DST
PPAS-------S-CSDSLLSDVPSE-------SPVDRFAGLDLRPD----GTDLQEDEFDMRAPYISMSGDFPLLPPDPQDSPQ--GSPT----------
--------PKSSLAALLVSPELPDWGAAAATGRNAGDTAGDGRRHGVYV--TAPLEQK
>tr|C0HAF0|C0HAF0_SALSA Hypoxia-inducible factor 1 alpha OS=Salmo salar GN=HIF1A PE=2 SV=1
----PEKKSRVSSERRKEKSRDAARYRRGKESEVFYELAQELPLPHSVTSNLDKASIMRLAISYLHMRKLLSTDDKTVEEESEMDSQLNVSYLKALEGFL
MVLSEDGDMIYLSENVNKYLGLAQFDLTGLSVFEYTHPCDHEELREILVHRT-TKKSKGPNTERSFFLRMKCTLTSRGRTVNVKSATWKVLHCSGHV---
-APAEQNPCGHKEPPVSYLVLVCDPIPHPSNIEAPLDTKTFLSRHTLDMKFTYCDERT-ELMGYDPEDLLNRSVYEYYHALDSDHLIKTHHNLFVKGQVS
TGQYRMLAKIGGFVWVETQATVIYNNKNSQPQCVVSVNFVLSGIE-EKMVLSLEQTEDMRSVKKELV------------------------------EEE
-ELFTQAMEP-PLASLYDRLKEEPEALNLLAPAVGDTIISLDFSNPD---ILLKEVPLYNDVMLPSTSDKLALPHSMQPPSEQPLIPSA--------DST
P----------PDIALNFCFPMDSDISAALKLDLVERLFAIDTEPKTPFTSQGMEDLDLEMLAPYIPMDDDFQLRLS-PEEPLS----SP-------LTQ
DVHSYTDSPFSAPSIRTASP---PA----------APQMDREIYLRTLATQ-SQRKRK
>tr|A5H732|A5H732_ESOLU Hypoxia-inducible factor 1 alpha OS=Esox lucius GN=HIF-1a PE=2 SV=1
----PEKKSRVSSERRKEKSRDAARCRRGKESEVFYELAQELPLPHSITSNLDKASIMRLAISYLRMRNLLSTDEGAVEEESELDSQFNGSYLKALEGFV
MVLSEDGDMIYLSENVNKCLGLAQFDLTGLSVFEYAHPCDHEELREMLVYRT-TKKSKEPNTDRSFFLRMKCTLTSRGRTVNVKSATWKVLHCSGHVRVH
EVPAEQGSCGHKEVPVPYLVLVCDPIPHPSNIEAPLDTKTFLSRHTLNMKFTYCDERT-ELMGYNPEDLLNRSVYEYYHALDSDHLTKTHHNLFTKGQVS
TGQYRMLAKRGGFVWLETQATVIYNNKNSQPQCVVCVNYVLSGIEEEKLVLSLEQIEDMRPVKKERI------------------------------EEE
EVLFTQAMEK-PVTSLYDRLKAEPEALTVLAPAAGDTIISLDFSSPD---VLLKEVPLYNDVMLPSTSDKLALPLSLLPPSEQPLAPLC--------DSN
P----------PDGPLDFCFPMDSDINSAFKLDLVESLFAIDTEPKTPFSSQAMEDLDLEMLAPYIPMDDDFQLRLS-PEEPLT----SP-------LTK
EVHNYPGSPFSAPSSQTTSPAPASA----------AP---QEISLSKLVTQ-AQRKRK
>sp|Q98SW2|HIF1A_ONCMY Hypoxia-inducible factor 1-alpha OS=Oncorhynchus mykiss GN=hif1a PE=2 SV=1
----PEKKSRVSSDRRKEKSRDAARCRRGKESEVFYELAQELPLPHSVTSNLDKASIMRLAISYLHMRNLLSTDNE--EEEREMDSQLNGSYLKAIEGFL
MVLSEDGDMIYLSENVNKCLGLAQIDLTGLSVFEYTHPCDHEELREMLVHRT-TKKSKEPNTERSFFLRMKCTLTNRGRTVNVKSATWKVLHCSDHVRVH
ESPAEQIPGGHKEPSVPYLVLVCDPIPHPSNIEAPLDTKTFLSRHTLDMKFTYCDERT-ELMGYDPEDLLNRSVYEYYHALDSDHLMKTHHNLFAKGQVS
TGQYRMLAKRGGFVWVETQATVIYNNKNSQPQCVVCVNYVLSGIEEEKMMLSLEQTEDMRPVKKELE---------------------------------
--LFTRAVET-PLSSLYDRLKEEPEALTLLAPAAGDTIISLDFSSPD---ILQKEVPLYKDVMLPSTSDKLALPLSLLPPSDQHLVPNT--------DST
P----------PDSPLDFCFPMESDINAEFKLDMVETLFAINPEPKTPFTLQAMEDLDLEMLAPYIPMDDDFQLRLS-PEEPLS----SS-------LTQ
EVHSYPGSPFNAPGSLTASPALAPA----------VPQMDREISLRSLASQ-AQRKRK
>tr|F1QNB9|F1QNB9_DANRE Hypoxia-inducible factor 1 alpha A OS=Danio rerio GN=hif1aa PE=2 SV=2
----PG-KKRVSSERRKEKSRDAARCRRGKESEVFYELSRELPLPHSVTSNLDKASVMRLALSYLRLRKLLNSDVLE-K-ETALDTQWNGSFLKALDGFL
LVLSADGDIVYLSENVSKCLGLPQIELTGHSVFEFTHPCDHEELREMLAHRF-LKKSKDQNTNRSFLLRMKCTLTSRGRTVNVKSASWKVLRCSGRIHTA
DGV-EKEVCEEKNTCSTYLVLICESIPHPANIEAPLDSRTFLSRHTLDMRFTYCDERT-ELLGFDPEDVLQHSVYEYYHALDSDHMTKTHHSLFVKGQVC
TGQYRLLAKAGGFVWAETQATVIYNSKNSQAQCVVCVNYILSGIEQPKQILSLQQTNSTKIKQEEHQ------------------------------E--
-----KEDEEC-PVVQHNSLKGETEALTVA-----DPVLTLDINITD-AISVLTEIPLYNDVMLPSSDV--LLPLSPLSPPCSSLNDD---------DQ-
-----------DSSRSQVDLPVDSELCDQLKPDHVEKHFSMDIESK----TQGV-GLDLEMLAPYIPMDDDFQLRVS-PVRPMC----TP-------STQ
TSPALSAAT---PDSLSCDPVQQKT----------EIIQD--SDISYKCQTPKLLKRK
>tr|A0A0B5KUA2|A0A0B5KUA2_9TELE Hypoxia-inducible factor 1 alpha A OS=Gymnocypris eckloni PE=2 SV=1
----PG-KKRVSSERRKEKSRDAARCRRGKESEVFYELARELPLPHGVTSNLDKASVMRLALSYLRLRKLLNTDVLN-V-ESELDSQWNSSYLKALDGFL
MVLSADGDIVYLSENVSKCLGLPQIDLTGHSVFEFTHPCDHEELREMLAHRT-LKKAKEQHTNRSFLLRMKCTLTSRGRTVNVKSASWKVLRCSGQIHTT
DGI-KKGVCEEKNVCSTYLVLICESIPHPAYIEAPLDSRTFLSRHTLDMRFTYCDERI-ELLGFEPGDLLQHSVYEYYHALDSDHMTKTHHNLFVKGQVC
TGQYRLLAKAGGFAWAETQATVIYNSKNSQPQCVVCVNYILSGIEQPKQILSLQQTNSTKMKQDHEE------------------------------HHE
ES--NEKKEEC-E-ELCGS-------MTVA-----DLVLTLDITSTD-ALSVLTEIPLYNDVMLPSSSV--LLPLSPLSPPCSSLNDD---------DD-
-----------DSSRSQVDFPVDSELSDQLKPDHVERLFSMDIESKTPFNTQGV-GLDLEMLAPYIPMDDDFQLRVS-PAESMC----TP-------STQ
TAPALPGAP---LDIVSRDTVPQRT----------EMIQDDESDISSKCQTTKLLKRK
>tr|Q3S3U2|Q3S3U2_DICLA Hypoxia-inducible factor OS=Dicentrarchus labrax PE=2 SV=2
----PETESRVSSERRKEKSRDAARCRRGKESEVFYELAQELPLPHSVSSSLDKASIMRLTISYLRMRKLLNTDEPM-KEETDLDLQLNSSYLKALEGFL
MVLSEDGDMIYLSENINKCLGLAQFDLTGHSVFDFIHPCDQDELREMLVHRT-GKKSKEPNTGRSFFLRMKCTLTSRGRTVNVKSATWKVLHCSGHVHVY
DSHTEESTNGQKEPPIPYLVLICDPVPHPSNIEVPLDSKTFLSRHTMDMKFTYCDERT-ELMGYDPEDLLNRSVYEYYHAQDSDHLTKTHQNLFAKGQVC
TGQYRMLAKRGGFVWVETQATVIYNNKNSQPQCVVCVNFVLSGIQEEKLILSLEQIEDVKPVKAELQ------------------------------QGE
EKLFTQAVAA-SLVSLYDRLKEEPEALTLLAPAPGDTIISLDFSCPD-EIPMMNDVPVYNDVMLPSTSDKLALPLSPLPPSEPLHVTT---------APT
PAS--------PGSPLDFCFPMESDMSSDFKLDLVEKLFAIDTEPKTPFTTQAPEDFDLETLAPYIPMDDDFQLRVT-PDEPLS----SP-------VTQ
DVHCY-----KSPGSRTASPAPPLA----------TTQLDKEVSLSTLAAQ-TPRKRK
>tr|M9NZ78|M9NZ78_SPAAU Hypoxia inducible factor-1 alpha OS=Sparus aurata GN=HIF-1 PE=2 SV=1
----PEK-KRVSSERRKEKSRDAARCRRGKESEVLYELAQELPLPHSVSSSLDKASIMRLTISYLRMRKLLSTDEPM-AEEKELDLQLNSSYLKALDGFL
MVLSEDGDMIYLSENINKCLGLAQFDLTGHSVFDFIHPCDQEELREMLVHRT-GKKAKETNTERSFFLRMKCTLTSRGRTVNVKSATWKVLHCSGHVRVY
ESHTEETPNGQKEPPVPYLVLICDPIQHPSNIEVPLDTKTFLSRHTMDMKFTYCDERT-ELMGYDPEDLLNRSVYEYYHAQDSDHLTKTHHNLFAKGQVC
TGQYRMLAKRGGFVWVETQATVIYNNKNSQPQCVVCVNFVLSGIQEEKLILSLEQTEDVKPIKEEPQ------------------------------HDT
DQLFTRVAEA-SVASLYDQLKEEPEALTLLAPAAGDTIISLDFSSPD-EIQLLHDVPLYNDVMLPSISDKLVLPLSPLPPSEPLHITTT--------ATS
LAS--------TDSPMDFCFPMDSEMSSDFKLDLVEKLFAIDTEPKNPFTTQAMED--LEMLAPYIPMDDDFQLRLP-PDEPLT----SP-------VKQ
DIPSYPSSPFSSPGSRTASPAPPLA----------TTQLNKEVSLGTLAAL-TQRKRK
>tr|Q2ESI1|Q2ESI1_MICUN Hypoxia-inducible factor 1 alpha OS=Micropogonias undulatus PE=2 SV=1
----PEK-KRVSSERRKEKSRDAARCRRGKESEVFYELAQELPLPHSVSSSLDKASIMRLTISYLRMRKLLSTDEPI-AEETDLDFQLNGSYLKALDGFF
MVLSEDGDMIYLSENINKCLGLAQFDLTGHSVFDFTHPCDHEELREMLVHRT-GKKAKEPNTERSFFIRMKCTLTSRGRTVNVKSATWKVLHCSGHVRVS
DSCTEQTTSGQKEPPVPYLVLICDPIPHPSNIEVPLDTKTFLSRHTMDMKFTYCDERT-ELMGYDPDDLLNRSVYEYYHAQDSDHLTKTHHNLFAKGQVC
TGQYRMLAKRGGFVWVETQATVIYNNKNSQPQCVVCVNFVLSGIQEEKLILSLEQTEDVKPVKEELQ------------------------------PEE
EELFTRAIES-TLVSLYDQLKEEPEALTLLAPAPGDTIVPLDFSCPD-EIQ----LPLYNDVMLPSTSDKLALPLSPLPPSEPLHVTTS--------APT
TAS--------ADSPLDFCFPMDSDMSSDFKLDLVEKLFAIDTEPKTPFTTQAVEDLDLEMLAPYIPMDDDFQLRLP-QEEPLS----SP-------VTQ
DIQSYPSSPFSSPGSRTASPAPPLA----------TTQLGNEVSLRTLAAQ-SQRKRK
>tr|A5H736|A5H736_GASAC Hypoxia-inducible factor 1 alpha OS=Gasterosteus aculeatus GN=HIF-1a PE=2 SV=1
----PEK-KRVSSERRKEKSRDAARCRRGKESEVFYELAQELPLPHSVTSGLDKASIMRLIISYLCMRKLLHNDEPV-TEETELESQINSAYLKALDGFL
LVLSEDGDMIYLSENVNKCLGMAQFDLTGQSVFDFIHPCDQEELREMLVHKT-GKKAKEADTKRSFFLRMKCTLTNRGRTVNVKSATWKVLHCSGHVRVH
DNPTEETSNGHKEPPAPYLVLICDPIQHPSNIEVPLDTKTFLSRHTMDMKFTYCDERT-ELMGYDPEDLLDRSVYEYYHALDSDHLNKTHHNLFAKGQVS
TGQYRMLAKRGGFVWVETQATVIYNNKNSQPQCVVCVNFVLSGIQEEKLILSMDQIEGVKPVTEELL------------------------------QQA
EKLFTRAAEV-SPASLYDQLKAEPEALTLLAPAAGDAVISLDFSCPE-EILLVKEVPLYNDVMLPSTGDQLTPPLSPLPLSETLRVTAV--------ARS
STI--------ADSPLDFCYPMDSEMSSDFKLDLVERLFAIDTETKTPFTTQAMEDLDLEMLAPYIPMDDDFQLRLT-PEESLS----SP-------VTQ
DIHSYPSSPFSAPGSRTASPAP-PA----------IPQPDKEVSLMTLAAA-SQRKRK
>tr|D7R4L3|D7R4L3_9TELE Hypoxia-inducible factor 1 alpha OS=Callionymus valenciennei GN=HIF-1a PE=2 SV=1
----PEK-KRVSSERRKEKSRDAARCRRGKESEVFFELAKQLPLPPGSSSSLDKASIMRLTISYLRMRKLLGSDKAK-EAGSELDLHFNSSYLKALEGFL
MVLSEDGDMIYVSDNVNKCLGLAQLDLAGHSVFNFTHPCDQEELRETLQHRA-GKKSRDVNSARSFFLRMKCTLTSRGRTVNVKSATWKVLHCSGHLYDS
E---------PSDGSVPYLVLICDPIPHPSNIEVPLDTKTFLSRHTMDMKFTYCDERT-ELMGYDPDELLNRSVYEYYHALDSNHLTKTHHNLFAKGQVI
TGQYRMLAKRGGFVWVETQATVIYNNKNSQPQCVVCVNFVLSGVQEEQTILSLEQTQDVKSVKEEKA------------------------------QEE
ESLLSPAQED-PPSSLYERLKEEPEGLTQLAPAAGDTIISLDFSCPD--VHIL-KDPLYNDVMLPSTSSKVALS----PPSEASAKASA--------NT-
-----------VVTSLDFCFPVDSDMNPDFKLDLVEKLFTINTQPKTPFASQPLGDLDLDMLAPYIPMDDDFQLRLN-PDEPVR----SP----------
-LHDYSSS----PASRTRSPEP-LA----------TPQLDKEVSLRTLVAQ-AQRKRK
>tr|Q2PMW1|Q2PMW1_ORYME Hypoxia-inducible factor 1 alpha OS=Oryzias melastigma PE=2 SV=1
----PEK-KRVSSERRKEKSRDAARCRRGKESEVFYELATLLPLPHSVSSSLDKASVMRLTISYLRMRKLLGSDEPK-QEETELDMKFNSSYLKALDGFL
MVLSEDGDIIYLSENVNKCLGLAQFDLTGQNVFDYTHPCDQEELREMLVYRT-GKKAKEPNSERSFFLRMKCTLTSRGRTVNVKSATWKVLHCSGHVHVN
GVQAEQNSNGQKEPPVPYLVLICDPIPHPSNIEVPLDTKTFLSRHTMDMKFTYCDERT-ELMGYDPEDLLNRSIYEYYHALDSDHLTKTHHNLFAKGQVC
TGRYRMLAKSGGFVWVETQATVIYNNKNSQPQCVVCVNFVLSGIQEEKLIMSLDQIEDVKSVKEEPQ------------------------------EAD
EAHFKKMAQS-PFDTLYDQLKEEPEALTLLAPAAGDTIISLDFSQPE-EIHLLKDAPLYNDVMLLSTSDKLALPLSPLPPSEALSLSNT--------APT
LI---------TDSSIDYCFPMDSEENSEFKLDLVEKMFAIDTESKTPFNTQ---DLDLEMLAPYISMDDDFQLPVT-VEEPQP----SP-------VTK
DALSYPTPQLNPLSGCTASPGPPLP----------AGNLEKDVHPCSPAAP-TQRKRK
>tr|I3KW40|I3KW40_ORENI Uncharacterized protein OS=Oreochromis niloticus GN=LOC100703737 PE=4 SV=1
----PEKKSRATSERRKEKSRDAARCRRGKESEVFYELAQQLPLSHSVSSSLDKASIMRLTISYLRMRKLLSTDEPP-TEDAELDMQLNSSYLKALEGFL
MVLSEDGDMIYLSENVSKCLGLAQFDLTGHSVFDFTHPCDQEELREMLVHRT-GKKSKEPNTERSFFLRMKCTLTSRGRTVNVKSATWKVLHCTGHVRVY
DSPAEEGTNGQKEPPVPYLVLICDPIPHPSNIEVPLDTKTFLSRHTMDMKFTYCDERT-DLMGYDPEDLLDRSVYEYYHALDSDHLTKTHHNLFAKGQVC
TGQYRMLAKKGGFVWVETQATVIYNNKNSQPQCVVCVNFVLSGIQEEKLILSVKQTADVKPVKEEHQ------------------------------EED
-QILTDSAVT-LPVNLYDHLKGEPEALTMLAPAAGDTIVSLDFSCPG-DIHLLKDVPLYNDVMLPSTDDKLVLPLSPLPPSEPLNVSST--------AQT
TTS--------PGSPLDFCFPMDSEMNSDFKLDLVEKLFAIDTEPKTPFNTQEMEDFDLEMLAPYIPMDDDFQLLLP-PGEPLS----TP----------
-IHSYPSSPFSAPGSRTASPAPPPP----------APKLEKEVPLRTLAVQ-AQRKRK
>tr|A0A087XQT7|A0A087XQT7_POEFO Uncharacterized protein OS=Poecilia formosa PE=4 SV=2
----PEK-KRVSSERRKEKSRDAARCRRGKESEVFYELSKQLPIPHSTSSNLDKASVMRLTISYLRMQKLLCIDEPV-AETTELDIQLNGSYLKALDGFL
VVLSEDGDIIYISENVNKCLGLAQFDLIGHSVFDFTHPCDQEELREMLVYRS-GKKVKEPSTERNFFLRMKCTLTSRGRTVNVKSATWKVLHCSGHVRVH
SS--EQSANGHKEPPVPYLVLICDPIPHPSNIEVPLDTKTFLSRHTMDMKFTYCDERT-ELMGYDPEDLLNRSVYEYYHALDSDYLTKTHHHLFAKGQVT
TGQYRMLAKRGGFVWVETQATVIYNNKNSQPQCVVCVNFVLSGIQEEKLILSLEQTQEMKPVKKEEE------------------------------EEE
QQFQDLVIKQ-EQDCLYNLLKGHPDALMLLAPAAGDTIISLDFSRPG-ETHLLKDVPLYNDVMLPSSGGKLPLPLSPLAPTEPLEPASS--------ALK
PPN--------VDNPLGFSFPMDTEMNSDFKLDLVEKLFAIDPEPKTPFNTEAMEDSELEMFAPYISMDDDFQLPLG-PDEPLS----CP-------VTP
ELHSHPSSPFSAPESRTASPAPPPA----------VAQPEKEVPLRNLAAQ-VQRKRK
>tr|H3DIY3|H3DIY3_TETNG Uncharacterized protein OS=Tetraodon nigroviridis PE=4 SV=1
----VPEKKRVSSERRKEKSRDAARCRRGKESEVFYQLAQELPLPHSVSSSLDKASIMRLTISYLRMRILLNAGEPL-TEETDLDLQLNGCYLKALDGFL
MVLSEDGDMIYLSENISKCLGLAQFDLTGHSVFDFIHPCDQEELREMLIHRT-GKKAKEPNTERRFFLRMKCTLTSRGRTVNVKSATWKVLHCLGHVRVH
ESPAEPDPDGAQPSAVPYLVLICDPIPHPANIEFPLDTKTFLSRHTMDMKFTYCDE-T-ELMGYDPEDLLNRSVYEYYHAQDSDHLTKTHHNLFAKGQVC
TGQYRMLAKRGGFVWLETQATVIYNTKNSQPQCVVCVNFVLSGVQEEKMILSLEQTADVKPVKEELV------------------------------GSP
ADLLPEEADG-PLSSLYDHLKRRPGALTMLAPAAGDTVVPLDFSCPD-ELQLLKEVPLYNDVMLPSTSDKLVLPLSPLPPTGPLQVTSS--------ASA
AAS--------VDAPHDLCFCTDSDMSSDFKLDLVEKLFTIDTEPRTPLTTQAMEDLDLEMLAPYIPMDYDFQLRLS-PDEALP----SS-------LSQ
EIHSYPSSPFSSAGSRTPSPAPPLA----------TTQLNKEADLRMLAAQ-ATRKRK
>tr|H2U0Z2|H2U0Z2_TAKRU Uncharacterized protein OS=Takifugu rubripes GN=LOC101071027 PE=4 SV=1
----PEK-KRVSSERRKEKSRDAARCRRGKESEVFYQLAQELPLPHSISSSLDKASIMRLAISYLRMRKLLNAGEPI-TEETDLDLQLNGSYLKALDGFL
MVLSEDGDMIYLSENIIKCLGLAQFDLTGHSVFDFIHPCDQEELREMLIHRT-GKKAKEPNTERSFFLRMKCTLTSRGRTVNVKSATWKVLHCSGQVRVY
ENHTEPSPDEQKESAVPYLVLICDPIPHPANIEFPLDTKTFLSRHTMDMKFTDCDERT-ELMGYEPEDLLNRSVYEYYHAQDSDHLAKTHHNLFAKGQVC
TGQYRMLAKRGGFVWLETQATVIYNTKNSQPQCVVCVNFVLSGIQEEKMVLSLEQTADVKPVKEELL------------------------------QEE
--MLTEVTES-PVSSLYDKLKEKPEALTLLAPAAGDTIISLDFSCPD-EMQLLKEVPLYNDVMLPSTSEKLVLPLSPLPPSEPLHVAPT--------DST
PASS-------VDGPHDLCFCMDSDMSSDFKLDLVEKLFTIDTEPKTPFTTQAMEDLDLEMLAPYISMDDDFQLRLS-PDEALP----TS-------LTP
EVPSYPGSPFSLPDSCTASPAPPLAFK--------TTQLNKEVELRTLAAQ-TPRKRK
>tr|A0A067Y838|A0A067Y838_BRAFL Hypoxia inducible factor alpha subunit long form OS=Branchiostoma floridae GN=Hifa PE=2 SV=1
----LCRPKRRNSEKRKEKSRDAARVRRSKETEIFYELAHQLPLAHSKSAQLDKASIMRLAISYLKTRMIFADTEVV-KVESTTDQQMSDQYLKAMEGFV
LSLSDEGDILYLSENVCKYLGLTQLELTGHSIFDFTHPCDHEEIRDVLCTKN-----YTKNKACSFFMRMKCTLTSKGRNVNLKSATYKVIHCQGYLRSY
NNSQ-VNSLGCKEPPLLCLVAIGEPIPHPSNIEFPLDCKTFLSRHSMDMKFTYCDERITELLGHDPASLLGKGVYDYCHALDAERLERMHRCLYQKGQVT
TGQYRLLARRSGYAWVETQATIIYNNRTEKPQCIVCVNYVISDIEEEENVLSSEQASQKKFPKVEKI------------------------------EEE
PQFFW---------DGEQALRDSPEDLTRVAPAAGDAMIPLGFPSAD----------LFGSSSLPD----TSL--DPGFGQEDLFGSQQEKDTFSL-PAT
PLSD-------PNSDLDFMDQLMGRTTSDPDLTAINPSLALDTGPIAGKLTRPLTAEELSYRAPYIPAYQ--PLNPN---NAV-TVTSTPDSCCG--QEL
PFAAYASPQMMTMNGKHLRVAKVGG------NRTRTHMPGKHGPIGKLTFAGSKRKKL
>tr|H3B2A5|H3B2A5_LATCH Uncharacterized protein OS=Latimeria chalumnae GN=HIF3A PE=4 SV=1
----------------------------------------------------------------------------------------------------
------------------CCIFSQLELIGHSVFDFVHPCDLEELKDMLCPRQGFKKKKEVNTERSFFIRMKSTLTSRGRTVNLKSASWKVLQCTGHMKTY
TSSEH-PEDGYPDLPMTYLIMTCEPIPHPSNIEVLLDSRTFLTRHNMDMKFTYCDERITELAGYHPDELIGQSAYEYFHALDSDPLSKCIHDVLSKGQAV
TGLYRFLTREGGYMWTQTQATVIYNSKNSQPESIVCLNFVVSGIEEKDVVFSLEQRESQLKPIVKILEK-----------------------------RQ
----SNAMGADTKEDLFTKLKEDPEELTQLAPTPGDTIIPLDFSLTCKEPKVFVKPPDVSDAVFSATPEKFCSPELPIDPE-PRSVVS--GAQCLFKAGS
PGLTLVFSDPEGW-EQGLYAIVSSGEEFNLEMENVQKLFATNKEAQDTDI-SQVRSLDLEMLAPYISMDDDFQLTVMDQQPLKEDDALPKSCGGSMTIIN
QQEQLAD-EANGVKDTVETEVTTSSGTLSSPAKKRPLDLEDGLNSEALSVQNVKRRHC
>tr|A5H735|A5H735_SANLU Hypoxia-inducible factor 1 alpha OS=Sander lucioperca GN=HIF-1a PE=2 SV=1
----------------------------------------------------------------------------------------------------
------------------CLGLAQFDLTGHSVFDFIHPCDQDELREMLVYKTGPKTKE-SNTERSFFLRMKCTLTSRGRTVNVKSATWKVLHCSGHVRVY
DSHTEETPNGHKEPPVPYLVLICDPIQHPSNIEVPLDTKTFLSRHTMDMKFTYCDERITELMGYDPEDLLNRSVYEYYHALDSDHLTKTHHNLFAKGQVS
TGQYRMLAKKGGFVWVETQATVIYNNKNSQPQCVVCVNFVLSGIQEEKQILSLEQIEDVRPVKEEEKA-VVESSQPNMSPTLPKEEKGPELDVIKLFTQA
----VEA---QPLTSLYDQLKEEPEALTLLAPAAGDAIISLDFSC-DSEIQLLKEVPVYNDVMLPSTSDKLALPLYPLPPREPLHVTTT-------YAPA
TSTTTSHSSTEADSPLDFCFPMDSEMSSDFKLDLVEKLFAIDTEPKTPFNTQAMEDLDLEMLAPYIPMDDDFQLRSL---EALSGGPVKSLESSPVHVTQ
DIHSYPSSPFSAPGSRTASPAPLNAPNPATVVAKRTPQLDKEVSLRTLAAQNAQRKRK
>tr|D3XLC0|D3XLC0_PSEGE Hypoxia inducible factor-1alpha (Fragment) OS=Pseudochaenichthys georgianus GN=HIF-1alpha PE=4 SV=1
----------------------------------------------------------------------------------------------------
------------------CLGLAQFDLTGYSVFDFIHPCDQEELREMLVHKTGSKNKE-PNTARSFFLRMKCTLTSRGRTVNVKSAAWKVLHCSGHVRVY
DGCTEETPNGHKEPPVPYLVLXCDPIQHPSNIEVPLDTKTFLSRHTMDMKFTYCDERITELMGYDPEDLLNRSVYDYYHAMDSDHLTKTHHNLFAKGQVS
TGQYRMLAKRGGFVWVETQATVIYNNKNSQPQCIVCVNFVLSDIQEEKLVLSLEQMEDVKPVEEEEEQQQQQEEEEEEQQQQQQEEKGPELDVIKLFTQA
----AEA---QPFVSLYDQLKEEPEALTLLAPAAGDAIISLDFSC-DSEIQLLKEVPLYNDVMLPSTSDKLALPLSPLPPCEPLHVSTI-------FPSS
---TTSLRSTEAGSLMDFCFPMDSEMKSDSKLDFVEKLFAIDTDPKNLFTTQAMEDLDLEMLAPYIPMDDDFQLRSL---EPLSCGPVKSLQSSPIHITQ
DIHSYPFSPDSAPSSRTASPALLRAPQTAPIIAMRTPQLDKEVSLRTLAAQNAQRKRK
>tr|Q5IGQ2|Q5IGQ2_EPICO Hypoxia-inducible factor 1 alpha (Fragment) OS=Epinephelus coioides GN=HIF-1a PE=2 SV=1
----------------------------------------------------------------------------------------------------
------------------CLGLAQFDLTGHSVYDFIHPCDQEELREMLIHKIGSKTKE-PNTERSFFLRMKCTLTSRGRTVNVKSATWKVLHCAGHIRVY
DNHVEDTSNGHKEPPVPYLVLICDPIQHPSNIEVPLDTKTFLSRHTMDMKFTYCDERITELMGYDPDDLLNRSVYEYYHALDSDHLTKTHHNLFAKGQVS
TGQYRMLAKRGGFVWVETQATVIYNNKNSQPQCVVCVNFVLSGIQEEKMIFSLEQTEDVKPVKEEQMG-EEKVVVESSQPDMSPEEKVPELDVIRLFTQA
----VES---QPLVSLYDQLKEEPEALTLLAPAAGDAIISLDFSC-DSEIQLLKEVPLYNDVMVSSTSDKLALPLSPLPPSEPLDVTTT-------LAPA
PSTTTSHSSSETDSSLDFCFPMDSEMSSDFKLDLVEKLFAIDTEPKTPFSTQAMDDLDLEMLAPYIPMDDDFQLRSL---EPLSCGSVKSLQSSPVHVTQ
DIHSYPSSPFSAPSSRTASPAPLSARHPVTMVTKRTPQLDKEVSLRTLAAQNAQRKRK
>tr|L7NCR4|L7NCR4_CYNSE HIF-alpha OS=Cynoglossus semilaevis PE=2 SV=1
----------------------------------------------------------------------------------------------------
------------------CLGLAQFDLTGHSVFDFTHPCDQEELREMLIHRSGSKNKE-QNTERSLFLRMKCTLTSRGRTVNVKSATWKVLHCSGHVRVY
DNNTE-QTNGHKDPPVPYLILICDPIPHPSNIEAPLDTKTFLSRHTMDMKFTYCDERITELMGYDPEDLLNRSVYEYYHALDSDHLNKTHHSLFAKGQVS
TGQYRMLAKRGGFVWVETQATVIYNNKNSQPQCVVCVNFVLSGIQEEKLILSLEQTEDVKPVKEEQEEEKAEVLSGLSDMPLTLDTKVPELDVTKVFTQS
----VDT-----SSSLYDQLKGEPEALTLLAPAAGDTIISLDFSCSDSEIQLLNDAPLYNDVMLP--------------PSEPLNITVTT------YAPP
PPAATSNCSSETDSQLDFCFPMDS----DFKLDYVEKLFAIDTEPKTSFNSEIMADIDLEMLAPYIPMDDDFQLRCL---EPLTGVQVKSQHSSPLHIKQ
DLTSYPSS----PASRTASPALPESLNLARLIGKRSPQSDKDVSLRTLVAQNTQRKRK
>tr|Q30HW1|Q30HW1_PACBR Hypoxia inducible factor 1 alpha OS=Pachycara brachycephalum PE=2 SV=1
----------------------------------------------------------------------------------------------------
------------------CLGLEQFDLCGHSVFDYIHPCDQEELREMLVHKTGSKAKE-PNTERSFFLRMKCTLTSRGRTVNVKSATWKVLHCSGHVRVY
DT--EETPNGHQEPPVPYLVLVCDPIQHPSNIEVPLDTKTFLSRHTMDMKFTYCDERITELMGYDPEDLLNRSVYEYYHALDSDHLTKTHHNLFTKGQVS
TGQYRMLAKRGGFVWVETQATVIYNNKNSQPQCVVCLNFVLSGIQEEKLILSLEQIEDVKPVKEEEQQEEEKDVVESSQPDMSQEKKGPELDVIKLFTQA
----VEA---KPLASLYDQLKAEPEALTLLALAAGEAIISLDFSC-DSEILLLKEVPLYNDVMLPSTSDKLALPL-----SEPLRVATT-------YAPA
RCTS--SSSSEADSPLDFCYPMDSEMSSDFKLDLVEKLFAIDTEPKTPFTTQAMEDLDLEMLAPYIPMDDDFQLRSL---ESLSCGPVQSLQSSPVHVIQ
DIHSYPSSPFSAPGSRTASPAPLTAPHPATIVAKRTPQLDKEVSLRTLAAQNSQRKRK
>tr|T1Q054|T1Q054_9TELE Hypoxia-inducible factor 1 alpha subunit OS=Gymnocypris namensis PE=2 SV=1
----------------------------------------------------------------------------------------------------
------------------SMGPPQFDLTGHSIFEFSHPCDHEELREMLVHRTGSKTKE-QNTERSFFLRMKCTLTSRGRTVNIKSATWKVLHCAGHVRVQ
ERGEDSGDSGFKEPPLTYLVLICEPIPHPSNIEVPLDSKTFLSRHTLDMKFSYCDERITELMGYEPDDLLNKSVYEYYHALDSDHLTKTHHNLFAKGQAT
TGQYRMLAKKGGFVWVETQATVIYNPKNSQPQCIVCVNYVLSGIVEGDVVLSLQQTVTEPKAEEKENQAFEDEASEV--------------DILKLFKLK
----SLK-CPMKNLDLYEKLKEDSEALTVLAPAAGDTIISLDFNNSDSDMQLLKEVPLYNDVMLPSGSEKLSISLSPLTPSGSTPVLTKGAEDFPFSTNT
PSTSLGS--SGPNSPVNYCFQVDSDISSEFKLDLVEKMFANDTEAKTPFSSQAMEDLDPEMLAPYIPMDDDFQLH-P---DPLPSGPHSSRAPSPLHLLQ
EVCNAPVSPFSGT--RDVSPAR--IPQSSNQLNN------RELSPKMLAIQNAQRKRK
>tr|A5H737|A5H737_PLAFE Hypoxia-inducible factor 1 alpha OS=Platichthys flesus GN=HIF-1a PE=2 SV=1
----------------------------------------------------------------------------------------------------
------------------CLGLAQFDLTGHSVFDFTHPCDQEELREMLIHKTGSKTKE-SNTERSFFLRMKCTLTSRGRTVNVKSATWKVLHCSGHVRVY
DTKTEETSNGLKEAPVPYLVLICDPVPHPSNIEVPLDTKTFLSRHTMDMKFTYCDERITELMGYDPEDLLNRSVYEYYHAMDSDHLTKSHHNLFAKGQVS
TGQYRMLAKRGGFVWVETQATDIYNNKNSQPQCVVCVNFVLSGIQEEKLILSLEQTEDEILVKKEQKRQEKEEKVVVESILPDMAEKGPELDVIKLFTQA
----SKA---QPLASLYDQLKEKPEALTLLAPAAGDTIISLDFSC-DSEMQLLKDAPLYNDVMLPSSSEKLALPLSPLPPSEPLNTRGGF------YPPT
PSTTTCQRSSEADSPMDYCFPMDSDMSSDFKLDLVEKLFAIDTEPKTPFNTQAMEDLDLEMLAPYIPMDDDFQLRSL---EPLTSGQVKSLKSSPVQVTQ
QVDSYPSSPFSGVGSSTSSPAPLEVAHLATIIAKRTPQLDKEVSLRTLAAQNAQRKRK
>tr|W5LPR6|W5LPR6_ASTMX Uncharacterized protein OS=Astyanax mexicanus PE=4 SV=1
----------------------------------------------------------------------------------------------------
------------------CLGLPQIDLSGQSVFDLTHPCDHEEIREMLVHRTGSKIKEEPNTERRFLLRMKCTLTSRGRNVNIRSASWKVLHCSGHIRAP
VRVCVQDDCEDRGVPASYLVLICNPIPHPASIEKPLDSRTFLSRHTLNMHFTYCDDRIKELLGYDPKDLLQQSVYEYYHALDSDSLTKTHHNLFAKGQAC
TGQYRMLVKTGGFVWMETQATVIYNSKNSQPQCVVCVNYVLSGVEDPELVLSLHQSGSMVVKQEKKEEEEEEKKEEEEE----------EREKQECFQK-
----------IETAVLQDDLKEEPEVLNQLHFSSAACSASFTLKN-DIDAAVLKDVPLYNDVMLPSSSVLLPLSPLLPPPCASLPDTTAQLEDFSF----
STAGTTTCSTQPTSP------LTSDHSYQCKMNSEEEIFSIETETKTLLDAQAVKDLDLEMLAPYIPMDDDYQLRVHSPLQ---SGCVSADPPPPAQPLQ
SSSFYAFQCFTGFQDTNVSEL--E----TLQISSKTDSF--QVHGNMLALQQKLLKRK
>tr|G4WI71|G4WI71_MYXAS Hypoxia-inducible factor 1a OS=Myxocyprinus asiaticus GN=HIF-1a PE=2 SV=1
----------------------------------------------------------------------------------------------------
------------------SMGLTQFDLTGHSIFEFSHPCDHEELREMLVHRMGSKNKEMQNTERSFFLRMKCTLTSRGRTVNIKSATWKVLHCTGHVRVQ
ERSEESGDCGFKEPPQAYLVLICEPIPHPSNIEVPLDSKTFLSRHTLDMKFSYCDERITELMGHEPDDLLNKSVYEYYHALDSDHLTKTHHDLFAKGQAT
TGQYRMLAKKGGYVWVETQATVIYNPKNSQPQCIVCVNYVLCDIVEGNIVLSLQQTMTEPKAVVKESQEMEDEPSEV--------------DVLKLFRPE
----GLKHCKESSSSLYEKLKEQPEALAGLAPAAGDTIISLDFNNSDSDVQLLKEVPLYNDVMLPSSSEKLPMTLSCLTTSESIPPLTKTAEDFPF-SNT
PSTPLGS--SGPNCPMDYCFQVDSDISSEFKLDLVEKLFAIDTEAKTPFTTQDMEDLDLEMLAPYIPMDDDFQLHIP---EQLPSGLNSSRAPSPLHLLQ
KVCSAPVSHFSSS--REASPAR--TPQGGNQLNNRMPMGDRELSPKMQAIQNAQRKRK
>tr|W5LJA8|W5LJA8_ASTMX Uncharacterized protein OS=Astyanax mexicanus PE=4 SV=1
----------------------------------------------------------------------------------------------------
------------------CMGLTQFDLTGHSVFDFAHPCDHEEMREMLVHRTGSKTKE-QNTERSFFLRMKCTLTSRGRTVNIKSATWKVLHCTGHVRVQ
ESGEGSADSSFREPPITYLVLICEPIPHPSNIEVPLDSKTFLSRHTLDMKFSYCDERITELMGHEPDDLLNRSVYEYYHALDSDHLTKTHHNLFAKGQAT
TGQYRMLAKKGGYVWVETQATVIYNPKNSQPQCIVCVNYVLSGIVEGDMILSLEQTVTEPKAVEKEEKQKDKEEETE--------------VDMDSFKQE
----KLTCSVESLESLYEKLK-EPEALTVLAPAAGDTIISLDFNSSESEMQLLKEVPLYNDVMLPSTSEKLPLPLSPLAPSEPPPALDKGGEEFAFAANT
PSTPTGSSTSAPNSPIDYCFQVDSDIGSEFKLDLVEKLFAIDTEAKTPYSTQDMGDLDLEMLAPYIPMDDDFQLLIP---DPLPSGPHTSRVPSPLHMLQ
EVRSAPVSPFSGNRSREASPAR--TPQGSRTLTTGMSAVDRELSPKVLAIQNAQRKRK
>tr|V9P247|V9P247_CLABA Hypoxia induced factor 1 alpha OS=Clarias batrachus GN=HIF-1 alpha PE=2 SV=1
----------------------------------------------------------------------------------------------------
------------------CMGLTQFDLIGHSIFDFAHPCDLEEVREMMVHRPGSKTKV-QNTERSFFLRMKCTLTSRGRTVNIKSATWKVLHCTGHVRVQ
EHSDGSGEGGFKEPSVTYLVLICEPIPHPSNIEVPLDSKTFLSRHTLDMKFSYCDERITELMGHEPDDLLNRSVYEYYHALDSDHLNKTHHNLFAKGQAT
TGQYRMLAKKAGYVWVETQATVIYNPKNSQPQCIVCVNYVLSGIVEEDTVLSLQQTLPEKTEEKEEELQIEHEDSSV-------------MDMMKLFKKD
----HLSCSVESPKSLYDTLKDEPEALTVLAPAPGDTFVSLDFDSPDSDLQVLKEVPLYNDVMLPSTSEKLPLPLSPLAPSDPSPALVKGGEEFSITAST
PPSSSS---SEASSPSH-YFHVDSDI--NFKLDLVEKMFATDTESNSDFNTDEMGDLDLEMLAPYIPMDDDFQLHIP---NPLPSGPQTSHVPSPLHLLQ
ELSSIFGTPFN-----EASQTL--SPEPGIPLAKRMQVDDDEFASKVLTVQNGQRKRK
>tr|Q1L608|Q1L608_ICTPU Hypoxia induced factor 1 alpha OS=Ictalurus punctatus PE=2 SV=1
----------------------------------------------------------------------------------------------------
------------------CMGLTQFDLTGHSIFDFTHPCDHEEVREMLVHRTGSKTKE-QNTERSFFLRMKCTLTSRGRTVNIKSATWKVLHCTGHVRVQ
EHSESSGGVGFKEPSITYLVLICEPIPHPSNIEVPLDSKTFLSRHTLDMKFSYCDERITELMGYEPDELLNRSVYEYYHALDSDHLSKTHHNLFAKGQVT
TGQYRMLAKKAGYVWVETQATVIYNPKNSQPQCVVCVNYVLSGIVEEDMVLSLQQTVPEKDCGEEEELQVEQEDKSV-------------MDMMKLFKKD
----PLTCSVESSKSLYEKLKDKPEALTVLAPAAGDTIISLDFDSPDSEIHVLKEVPLYNDVMLPSTSEKLPLPMSPLAPSDPSPDLVKRGEEFSFTANT
PSISSS---SEPSSPAD-YFHVDSDIGSEFKLDLVEKMFATDTEADTHFNTDEMCDLDLEMLAPYIPMDDDFQLHIP---DPLSSGPQTPHVPSPLHLLQ
EVSSIFVTSFD-----EASGAH--TPQTGK-AAKRMQVEDQDLSTKSLN---VQRKRK
>tr|T1Q049|T1Q049_9ACTI Hypoxia-inducible factor 1 alpha subunit OS=Lepisosteus platostomus PE=2 SV=1
----------------------------------------------------------------------------------------------------
------------------CMGLTQFDLTGHSVFDFTHPCDHEEMREMLTYRTGSKKAKEQNSERSFFLRMKCTLTSRGRTVNIKSATWKVLHCTGHIQVY
ESSDGHNNCGYKEPPMTYLVLICEPIPHPSNIEVPLDSKTFLSRHSLDMKFSYCDERITELMGYQPEDLLGRSVYEYYHALDSDHLTKTHHDLFAKGQAT
TGQYRMLAKKGGFVWVETQATVIYNTKNSQPQCIVCVNYVLSGVVQEDLVFSLGQTESV-LKPLE----SPDVEM------------------PKIFTKA
----E---DLESSNTLFEKLKEEPEALTLLAPAAGDTIISLDFTSSDSEIQPLEEVPLYNDVMLPSSSEKLPLSPLPPDPALNVEVVSKSADPPSFSDSS
PSGTTRQNSPEPSSPGDYCFQVDSDIGSEFKLDLVEKLFAIDTEAKTPFATQTMDDLDLEMLAPYIPMDDDFQLRTLDPLETLSASAPVARAASPLHLVQ
EVRNALNSPFSGSRSRTSSPAPSSTSSAT-SPSRRIPALEGALSPKMLAIQNAQRKRK
>tr|A0A0P7YFP3|A0A0P7YFP3_9TELE Hypoxia-inducible factor 1 alpha subunit-like OS=Scleropages formosus GN=Z043_116106 PE=4 SV=1
----------------------------------------------------------------------------------------------------
------------------CLGLAQFDLTGHSVFDFTHPCDHEELREMLVHRTGPKKAKEKNTERSFFLRMKCTLTSRGRTVNVKSATWKVLHCTGHVRVY
ENIEGESHCGYKEPPVPYLVLICEPIPHPANIEVPLDSKTFLSRHTLDMKFSYCDERVTELMGYEPEDLLNRSVYEYYHALDSDHLTKTHHNLFAKGQAT
TGQYRMLAKKGGYVWVETQATVIYNTKNSQPQCIVCVNYVLSNIVEEKLVLSLEQTEKDVKGDVKEDVEDVNEDTEELKFSE---PTGLEADMIKLFTKA
----EDT---ECADSLYDKLKEEPDGLTMLAPAAGDTIIHLDFSCPDPEQPLLKEVALYNDVMLPSTSVKPPLPPSEPDPPLSTKVRAKGSEDFPFSSRT
TPGPAGRASPQPDSPLDFCFQVDSDIGSEFKLNLVEKLFAIDTEPKTPFT-QAMEDLDLEMLAPYIPMDDDFQLHVL---ESLAST---RHAASPLHLLQ
EVQSAPCSPFSGSCSRTSSPAPPDIPRCATPVGKRITGADVELSPKMLALHNAQRKRK
>tr|T1Q061|T1Q061_POLSP Hypoxia-inducible factor 1 alpha subunit OS=Polyodon spathula PE=2 SV=1
----------------------------------------------------------------------------------------------------
------------------CMGLTQFELTGHSLFDFAHPCDHEELREVLTHRTGSKKGKEQNTERSFFLRMKCTLTNRGRTVNIKSATWKVLHCTGHIRVC
DPPKGEDNCGYKEPPMTSMVLICDPIPHPSNIEVPLDSKTFLSRHSLDMKFSYCDERITELMGYQPEDLLGRSVYEYYHALDSDHLTKTHHDLFAKGQAT
TGQYRMLAKKGGFVWVETQATVIYNTKNSQPQCIVCVNYVLSGVVGEDLVFSLGQTENI-LKPVE----SPDADV------------------TKLLMQV
----D---PEESTNSLFEKLKEEPEALTLLAPAAGDTIISLDFSKSDSEIKKLDAVPLYNDVMLPSSSEKMLMSPLPPDPVLNLEVVTKNPEPLGILS--
--LPTTQSSPEPSSPSDYCFNVKTDIYGEFKMDLVEKLFAIDTEVRTPFTTQVADDFDLEMLAPYIPMDDDFQLRTLDQLEPVSASPPDMNIVSPLHMME
EVKSAPNSPFSGKNSRTESPIRKSLVPVTPLISKRPTAFSEELSPK----TLAQRKRK
>tr|T1Q067|T1Q067_POLSE Hypoxia-inducible factor 1 alpha subunit OS=Polypterus senegalus PE=2 SV=1
----------------------------------------------------------------------------------------------------
------------------CMGLTQFELTGHSVFDFTHPCDHEELREVLTHRAGAKKGKEVNTERSFFLRMKCTLTSRGRTVNIKSATWKVLHCLGHIRAY
ESCE-ENDCGYKKPLVTSLVVICEPIPHPSNIEVPLDSKTFLSRHSLEMKFSYCDERITELMGYQPEDLLGRSVYEYYHAMDSDHLTKTHHNLFAKGQAT
TGQYRMLAKNGGYVWVETQATVIYNSKNSQPQCIVCVNYVLSGVVEKDLIFSLSQTETLPVKAIE----DPELET------------------VKVTGKT
----V---PEGDGDSLFDKLKEEPEALTVLAPAAGDTIISLDFSTTESEMSSFEEVPLYNDVMLPSPNEKMLMSPVSSDPALNLEVAVKNAEPLELSRTS
SSLQSTQSSPGPNSPVDYSFEVDSDISSEFKLDLVEKLFAIDTEAKTSFVSQAGDDLDLEMLAPYIPMDDDFQLRTMDQMESLPSNPLILRTVSPLHMIH
NVQSLSDSSFSIQTNEAASLLNNSAESIQTLLGKTICTLDEELSPR----TCAQRKRK
>tr|A0A0P7UQ91|A0A0P7UQ91_9TELE Hypoxia-inducible factor 3a-like OS=Scleropages formosus GN=Z043_109809 PE=4 SV=1
-PVSLSLGGRPSLEQRKVRSRDAARSRRSQETEVFYQLAHTLPFPRRVVSDLDKAAIMRVTLSFLRIHSLFHSGEVKVESAEEEEEAIDRFYPRALAGFI
MVLTEEGDMVFLSESVNKYVGITQLELLGQSVYDFVHPCDQEELRDVLTPRPGLKKKADQRSERNFFLRMKSTLTNRGRVVNLKSAAWRVLRCSGHMRTY
HAADKT-----GPPIGNFLILLCEPIPDPSGVEFPLDCSAFLSRHSTDLRFIDCDDRVTQLVGYQPEDLTGRSAYEFHHALDSDHMTKSLHILFSKGQVC
TNQYRFLAKSGGYVWAETQATVTYNSKTSQPEAVVCLNFILSGVEHADVVFSMEQTPSLKKPKTEPEEKEE-----------------------------
--------VGKGACAELLNLKELSEEVPQSSPTPGDVAVSKTESVEPKNLSF----------YRPPSPNTV---------PEFPQELCTPDLRQLL---S
PIF----DRPEAASV----VSKCSGEDQFMDKDSVEKFFTFKPVDTNESTAEGTESMDLDMLAPYISMDDDFQLTFFTQ---------------------
----------------------------------------------------------
>tr|T1Q063|T1Q063_POLSE Hypoxia-inducible factor 3 alpha subunit OS=Polypterus senegalus PE=2 SV=1
---------MPRSELRKERSRDAARSRRSQETEVFYQLAHTLPLPRGVTSHLDKAAIMRLTLSFLRMKRILQNDS-----FREAEDDIDGYYLNAIAGFV
MVLSSEGDLIYLSENVSKHLGVPQLELVGQSIFDFVHPCDQEELRDILTSRHGYKKKSDIQTERNFFLRMKSTLTSNGRTVNLKSATWKVLQCSGHLRTY
HTEEDS-----TKE-LTCLTLICEPVPQPSTIDFPLDSRTFQSRHTMDLKYTHCEDRVFELLGYQPEDLIGRSAYEYHHALDSDHITKSFHILLSKGQMS
TGHYRFLAKNGGFAWAETCATVLYNRKSSQPEGVICLTFILSGLEETEIVFSVEQTLRIMKLKKEPGSLDE-----------------------------
---------ENKENCLFLKTSETTEEHTGMATALENNSVPLPDYAQPKDLSF----------SRAP-NDSL---------PESPQDLCTPELRQLL---A
PIF----EKSVNEDSGIFMSSPRSVDEQAFDMDEIEKFFANKKESEMYAGVPQDEPLDLDMLAPYISMDDDFQLNFLSH---------------------
----------------------------------------------------------
>tr|A0A0F8CNY0|A0A0F8CNY0_LARCR Hypoxia-inducible factor 1-alpha OS=Larimichthys crocea GN=EH28_08916 PE=4 SV=1
-SSSSSSSCRTSSEQRKLRSRDAARCRRSQETEVFYELARTLPLPRRVSTHLDKSAIMRVSLSFLWLQRLLRPGGEKQKEEEEEGDPMDSFYPQALAGFI
MVMTEEGDMIYLTENVNRHIGITQLELLGQSIYDFVHPCDQEELRDLLTPRPGLKKPSEQPTERNFFLRMKSTLTSRGRTVNIKSATWKVLHCTGHVRPF
GGG-ST-----SPPAARVMTLLCEPIPHPSSVEFPLDTCTFLTRHSMDLRFTHCEGRVTELVGYKPDDLIGRSAYEFHHALDSDHVNKSLHTLLSKGQVN
TSHYRFLANSGGFVWAETQATVLYSSKTSQPEAVVCLNFILSAVEQPDVVFSVEQIRCGQAKTHTPAECG------------------------------
---------SSSSADLFLKLKEQPGELLQLAPEAGDVIVPLT---DFVELSF----------FSGSSPDSV---------PDHPQDLCTPQLRQLL---S
PIF----NPISPPVSLLLDPEPSSPSEEVMDTSEVEKFFAICPEDVQGDAKDDMEGMDLEMLAPYISMDDDFQLTFLSG---------------------
----------------------------------------------------------
>tr|H2L9F8|H2L9F8_ORYLA Uncharacterized protein OS=Oryzias latipes GN=LOC101165163 PE=4 SV=1
-EDETVAVKRTSSEQRKLRSRDAARCRRSQETEVFYELARTLPLPRKVCTHLDKAGIMRVTLSFLRMQQLLQPHEGDTKDEEEEEDPMDAFYPQALAGFV
MVMTEEGDMIFLTENVNKHIGITQLELLGQSIYDFVHPCDQEELRDLLTPRPGLKKSAEQPNEVNFFLRMKSTLTNRGRTVNIKSATWKVLHCSGHIRPF
S-G-SA-----APPGARVMTLLCEPIPHPSSVEFPLDTCTFLTRHSMDLRFTHCEGRVTELVGYKPEDLVGRSAYEFYHALDSDHMKKSLHTLLSKGQVS
TSHYRFLANNGGFVWAETQATVLYSSKTSQPEAIVCLNFILSSVEQPDVVFSVEQTRSGLLSKTESP---N-----------------------------
--------TPSSSARLFLKLKEEPEEILQLAPES-GDAVVLV--AAPVELSF----------SSPLSPDSV---------PDHPQELCTPQLRQLL---S
PIF----DTLTPSSSPESA--LSAAQEEVMDIGEVERFFALCPEDVQTQTLENVEEMDLDMLAPYISMDDDFQLTLLNT---------------------
----------------------------------------------------------
>tr|A0A060WKF5|A0A060WKF5_ONCMY Uncharacterized protein OS=Oncorhynchus mykiss GN=GSONMT00028434001 PE=4 SV=1
-TKEEPVGKRSSTDQRKVRSRDAARCRRSLETELFYKLAHTLPLPRRVSADLDKAAIMRVTLSFLRMHHLRSG-DTSEDVTDGDEDTVDAFYPRALAGFI
LVMTEEGDMIYLGDSVSKHLGIPQLELLGQSVYDFVHPCDQEELRELLAPRPGVKKKVQQHTEINFFLRMKSTLTSRGRTVNIKSATWKVLHCTGHMRVC
CSGEDS-----SPPAGSFMTVLCEPIPHPSSVEFPLDRSTFLTRHSMDLCFTHCDGRVSELVGYEPEDLIGKSAYKFHHALDSDHVTKSLHILLSKGQVC
TSLYRFLAKSGGFVWAETQATVIYNNKTSQPEAVVCLNFILSVVEQADVVFSVEQTGCGLKSDPVSEASE------------------------------
---------NSSSAELSLQLKENQEDLLQLAPVSGDPIVPLT---DFAEPSF----------SLPSSSDSA---------PDFPQELCTPELWKLL---S
PIF----SKLTSSAPAL-VRTLIPIEELPIE-DEVAKLFAVCPDESVRNQPEDMEVVDLDMLAPYISMDDDFLLSV--Q---------------------
----------------------------------------------------------
>tr|G3PIK9|G3PIK9_GASAC Uncharacterized protein OS=Gasterosteus aculeatus PE=4 SV=1
-KAETVVVKRTSSEQRKLRSRDAARCRRSQETEVFYELSSTLPLPRRVCTHLDKSAIMRVALSFLRMHHFLLQPGEKRVSSSPMEPPMDSFYPQALAGFI
MVMTEEGDMIYLTENVSTHIGIPQLELLGQSIYDFVHPCDQEELRDLLTPRPGSKKPARQSSERNFFLRMKSTLTSRGRTVNIKSAAWKVLHCTGHVRQL
GGA-SA-----VPPVGGVMTLLCEPIPHPSSVEFPLDTRTFLTRHSMDLHFTHCEGRVTELVGYKPEDLIGRSAYEFHHALDSDHVNKSLHTLLSKGQVS
TRHYRFLANGGGFVWAETQATVLYNSKTSQPEAVVCLNYILSGVEQPDLVLSAEQTRCVRPHEAELCTPAV-----------------------------
--------APSSAAVLVFKLKEESEEVLQLAPEVVNPIGPLT--GEFVGLSF----------SNPPSPNSL---------PDHPQDLCTSQLRQLL---S
PIF----SPMTPPSSSSLDVESISCEEEVTDTSEVERFFAVWPDGQKVEPMEQMEVMDLEMLAPYISMDDDFQLTVHSS---------------------
----------------------------------------------------------
>tr|H2T9X1|H2T9X1_TAKRU Uncharacterized protein OS=Takifugu rubripes GN=LOC101062698 PE=4 SV=1
-KEESISIKRSSSEQRKLRSRDAARYRRSQETEVFYELAHTLPLPRRVSTHLDKSAIMRVALSVLRMRQLVQAASESQK-KEPEEDPMDIFYPQTLGGFI
MVLTEEGDMIYLTENVNKYIGIVQLELLGQSVYDFIHPCDQEELTDLLTPRPGLKKLKDLPNDLNFFLRMKSTLTNRGRTVNIKSAEWKVLHCTGHMCPF
GGE-PS-----SPAAARVMVLLCEPIPHPSSVEFPLDTYTFLTRHSMDLRFTHCEGRVTELVGYKPDDLIGRSAFEFHHALDSDHISKSLRTVLSKGQVS
TRHYRFLANNGGFVWAETQATVLYSGKTSQPEAIVCLNFILSSVEQPEFVFSIEQVHSDPPEANVPALAP------------------------------
---------SSNAADLFFKLKEKPQELLQLAPEAGD-VVPLT--ADFSKLSF----------FSPSSPDTM---------PENPQDLCSPQLLQLL---T
PIF----SPMTPPSSSTDAELPQSASEEVMDTSKVEKFFTIRPENSQGEKLKDSEEMDLAMLAPYISMDDDFQLTFLSS---------------------
----------------------------------------------------------
>tr|Q5IGQ1|Q5IGQ1_EPICO Hypoxia-inducible factor 4 alpha OS=Epinephelus coioides GN=HIF-4a PE=2 SV=1
-KEEAVAVRRTSSEQRKLRSRDAARCRRSQESEVFYELAHTLPLPRRVCSHLDKSAIIRAAISFLRMHHLL-QPGEKQKESNEEEDPMDAFYPQALAGFI
MVMTEEGDMTYLTENVSRYIGITQLELLGQSIYDFVHPCDQEELRDLMAPRPGLKKPAQQQNERNFFLRMKSTLTSRGRTVNIKSAAWKVLHCTGYIHQF
DGS-SR-----LSPAGRVMTLLCEPIPHPSSVEFPLGTCTFLTRHSMDLCFTHCEGRVTELVGYKPEDLIGRSAYEFHHALDSDHVNKSLHTLLSKGQVS
TRHYRFLANSGGFVWAETQATVLYSSKMSKPKAVVCLNFVLSAVEQADVVFSMEQVRRGQPAEAEPLSPAL-----------------------------
--------APSNSAELSFKLKEQPEELLQLAPAAGDIIVPLS--GENFELSF----------TRPVSPKSV---------PDNPQDLCTPQLRKLL---S
PIF----SPITPPSSSQNP-KRSPCEDEVLDNGEVDSFLAVWREVFQGQTLEDMEEMDLEMVAPYISMDDDFQLTVLSS---------------------
----------------------------------------------------------
>tr|I3JLN1|I3JLN1_ORENI Uncharacterized protein OS=Oreochromis niloticus GN=LOC100708832 PE=4 SV=1
-KEGVVAVKRTSSEQRKLRSRDAARCRRSQETEVFYELAHTLPLPRRVSTHLDKAAIMRVTLSFLRMHHLLRSDKNLKEEEEKDEDPMDAFYPQALAGFI
MVMTEEGDMIYLTENVNKHIGITQLELLGQSIYDFVHPCDQEELRDLLTPRPGLKKSTEQTSERNFFVRMKSTLTTRGRTVNIKSATWKVLHCTGQIRPF
GSG-SA-----SPPAGRVMTLLCEPIPHPSSVEFPLDTCTFLTRHSMDLRFTHCEGRVAELVGYKPDDLIGRSGFEFLHALDSDHINKSLHTLLSKGQVS
TSQYRFLANNGGYVWAETQATVLYNSKTSQPDAIVCLNFILSSVEQPDVIFSMEQTRCSRVPKIEPADEDS-----------------------------
---------SSSSAKLFMELREKPEELLQLAPDAGDTIVPLS--PGSVELSF----------ASPPSPDSV---------PEHPRDLCTPQLRKLL---A
PIF----DPITPPPSASPEPEQSRSEEEVMDTSEVEKFFAFWPEDAQD-TLVEMEGMDLDMLAPYISMDDDFQLTFLSS---------------------
----------------------------------------------------------
>tr|Q6STN7|Q6STN7_CTEID Hypoxia-inducible factor-1alpha OS=Ctenopharyngodon idella GN=hif-1alpha PE=2 SV=1
-TGVVTEKKRVSSERRKEKSRDAARSRRGKESEVFYELAHQLPLPHNVTSHLDKASIMRLTISYLRMRKLLSSDDTDKE--NELEGQLNGFYLKALEGFL
MVLSEDGDMVYLSENVSKSMGLTQFDLTGHSVFEFSHPCDHEELREMLVHRTVSKTK-EQNTERSFFLRMKCTLTSRGRTVNIKSATWKVLHCAGHVRVQ
ERSEGS---------LTYLVLICDPIPHPSNIEVPLDSKTFLSRHTLDMKFSYCDERITELMGYEPDDLLNRSVYEYYHALDSDHLTKTHHNLFAKGQAT
TGQYHMMAKKGGFVWVETQATVIYNPKNSQPQCIVCVNYVLSGIVEGDIVLSLQQTMTEPKAVEKESQKVE-----------------------------
--------DPMECSDLYEQLKEEPEALTVLAPAAGDTIISLDFNNSDSDMQLVKDVPLYNDVMLPSSSEKL---------PISLSALTTPALSKLE---T
RAE----DFPTPSTSGLMDYQVDSDISSEFKLDLVEKLFAIDTEAK-PFTNQAIEDLDLEMLAPYIPMDDDFQLRVPSP---------------------
----------------------------------------------------------
>tr|A0A087YH60|A0A087YH60_POEFO Uncharacterized protein OS=Poecilia formosa PE=4 SV=2
-EDGVVAVKRSSSEQRKLRSRDAARCRRSQETEVFYELARTLPLPRRVCTHLDKAGIMRVTLSFLRMQQLLRPEQSVKKEEEEEEDPMDAFFPQALAGFV
MVMTEEGDMVFLTENVNKHIGITQLELIGQSVYDFIHPCDQEELRDLLTPRPGLKKLAEQPSERNFFLRMKSTLTSRGRTVNIKSATWKVLHCTGHIRPF
--G-SA-----SPPAARVMTLLCEPIAHPSSVEFPLDSCTFLTRHTMDLRFTHCEGRVTELVGYKPEDLIGRSAYEFYHALDSDRIKKSLLTLLSKGQVN
TSPYRFLANSGGFVWAETQATVLYNNKTSQPEAVVCLNFILSAVEQPDVVFSVEQTRRSLLPKTEPSSPER-----------------------------
--------TAGSSAKLLLGLAEKPEELLQLADGGE---PPLT--AGGVELSF----------ASPPSPDTV---------PDHPKDLCSPQLRQLL---S
PIF----DGLNPSSSPASEPDLSPCEDEAMDTSEVERFFTICPEETQEQAAEDVEGKELEMYAPYISMDDDFQLTFLSD---------------------
----------------------------------------------------------
>tr|Q1L607|Q1L607_ICTPU Hypoxia induced factor-like factor OS=Ictalurus punctatus PE=2 SV=1
--MTTTEVKRPSSEQRKVRLRDAARCRRSQETEVFYELAHSLPLSRRITSHLDKAGIMRVTLSYLRMRHLLHSSWTKAA--EEEEDPTDAFYQQALAGFI
LVLNEDGDMVFLSDNVNKFIGITQLELLGQSVYEYVHPCDQEELRDLLTTKPGLKKK-DSCTECNFFLRLKSTLTSRGKTVNIKSATWKVVHCTGRMKTL
NQEGEG-----SSPVGSYMTLLCEPIPHPSCVEFPLDSSTFLTRHNMDLHFIQCDGRVTELVGYHPNDLIGRSAYDFIHALDFDHLTRSLHVLLSKGQVC
TYHYRFWLVNGGFVWTETHVHVLYNSRTSQPEAVVCLNFILSAVEEADTVFSVEQTRSEVNQDEPN--VIE-----------------------------
--------V-SSSSELFHRFKNDPEDLLQLAPAPGDTIIPLT---VNTELFF----------CPPSSPTTV---------PKCPKELCTPKLRQLL---S
PIF----DSSCPSSPD--L---SSADEVPMDTGEVEKFFANKPEET-KEPVQELDDMDLDMLAPYISMDEDFQLTFLPQ---------------------
----------------------------------------------------------
>tr|V9P0R0|V9P0R0_CLABA Hypoxia induced factor 3 alpha OS=Clarias batrachus GN=HIF-3 alpha PE=2 SV=1
--MTTTVAKRPSSEQRKVRLRDAARCRRSQETEVFYELAHSLPLSRRITSHLDKAGIMRVTLSYLRMRHLLHSSWTKVSTLEEEEEPTDAFYQQALAGFI
LVLSEEGDMVFLSENVNKFIGITQLELLGQCVYDYVHPCDQEELKDLLTTKPGLKKK-ESCTECNFFLRLKSTLTSRGKTVNIKSATWKVVHCTGYMKTL
NQEGEA-----SSLAVSYMTLLCEPIPHPSCVEFPLDSSTFLTRHTMDLHFSQCDGRVTELVGYHPNDLIGRSAYDFFHALDFDHLTRCLHVLLSKGQVC
TSRYRFLAKNGGFVWTETQATVLYNSKTSQPEAVVCLNFILSAVEEADVVFSIEQTRSDLMQDKLS--VIE-----------------------------
--------V--SSSELYHSLKDDPEDLLQLAPAPGDTIIPLT---GHTELFF----------VPPSSPNSV---------PKCPKELCTPKLRQLL---S
PIF----DSSCPTSPD--H---SSGDEFSMDTGEVEKFFADKPEET-KKTMEDMDDLDLDMLAPYISMDEDFQLTFLPK---------------------
----------------------------------------------------------
>tr|G4WI70|G4WI70_MYXAS Hypoxia-inducible factor 3a OS=Myxocyprinus asiaticus GN=HIF-3a PE=2 SV=1
--MVNSSGKRPSLEQRKVRSRDAARCRRSQETDVFYELAHSLPLPRRIASHLDKAAIMRVTLSYLRMNRLIQSGSTKT-SHEETEDPTDGFYQQALAGFV
MVMTEEGDMVFLSESVGKYIGITQLELLGQSVYEFVHPCDQEELRDILTTRPGLKKK-VKLTEHNFFLRMKSTLMHTGRTVNIKSATWKVLHCTGHIQTL
SSEDES-----STPGGSFLTLLCEPIPHPSSVEFPLDSSTFLTRHNMDLTFTQCDGRVTELVGYEPDDLIGRSAYEFYHALDFDHVTSSLHILFSKGQVC
TSHYRFLAKNGGFVWTETQATVLYNSRTSQPEAVVCLNFILSGVEQADVVFSLEQTSDKPLPKAVKLSLLE-----------------------------
--------EVSSTAELFLQMKENPEELLQLAPHSGDTIISLT---EGVDLSF----------GRPTSLNGI---------PECPQDFCTPELRQLL---S
PIF----DKPSNSPHA--A---SPAEELPVEMDGVEKFFALKPAESVKGQTENMDELDLDMLAPYISMDDDFQLTFLPQ---------------------
----------------------------------------------------------
>tr|W5KMK5|W5KMK5_ASTMX Uncharacterized protein OS=Astyanax mexicanus PE=4 SV=1
---MESSPKRPSSDLRKVRSRDAARCRRSQETEVFYELAHSLPLARRVTSHLDKAGIMRVTLSYLRMRQLLCSSTTKVEGTEEEQDPTDAFYQQALSGFV
LVLTEEGDMIFLSENVSKYIGLAQLELLGQSVYDFVHPCDQEELRDILTSKTGLKKK-EKFIEHNFFLRMKSTLTSRGRTVNIKSAAWKVLHCTGHMQTF
SSELES-----SSATGSYLTLLCEPIPHPSCVEFPLDSSTFLSRHSMDLNFTQCDGRVTELVGYHPDELVGRSAYEFFHALDFDHVTKSLHILFSKGQVC
TSQYRFLAKNGGFVWIETQATVIYSSKTSQPEAVVCLNFILSGVEQAETVFSVEQTRCELKSEKPSLPVIK-----------------------------
--------VSSSSAELFRKLKDNPEDLLQLAPAAEDTIILLT---EEMDLSF----------GPPSSPNGV---------PECPKDLCSPKLRQLL---S
PIF----DSPSPASPA--S---NSGDELSMDTGDVEKFFAIKPEENTKELTKELEEMDLDMLAPYISMDDDFQLTFLPQ---------------------
----------------------------------------------------------
>tr|Q6STN6|Q6STN6_CTEID Hypoxia-inducible factor-4alpha OS=Ctenopharyngodon idella GN=hif-4alpha PE=2 SV=1
--MVNSVNKRPSLEQQKVRSRDAARCRRSQETEVFYELAHSLPLPRRITSHLDKAAIMRVTLSYLRMNRLIQSVGPTK-KTEETENPTDGFYQQALAGFI
LVMTEEGDMIFLSESVSKYIGITQLELLGQSVYEFVHPCDQEELRDILTTRPGIKKK-EKLAEHNFFLRMKSTLTHTGRTVNMKSANWKVLHCTGHMQTF
SGDDET-----SLPAGSFLTLLCEPIPHPSSVEFPLDSSTFLTRHSMDLTFTQCDGRVTELVGYQPDDLIGRSAYEFYHALDFDHVTRSLHILFSKGQVC
TSHYRFLAKNGGFVWTETQATVLYNSRTSQPEAVVCLNFILSGVEEADVVFSLEQTCQKPKPKAEKLTVLE-----------------------------
--------EESSTATLFLKIKENPEELMQLAPHSGDTIISLR---EGVELSF----------CQPPSPNSV---------PECPQDFCTPELRQLL---S
PIF----DRPTKSPPA--A---SPAEELPMEMEGVEKFFALKPEESVKGQSEAMDELDLDMLAPYISMDDDFQLTFLPQ---------------------
----------------------------------------------------------
>tr|H2SME9|H2SME9_TAKRU Uncharacterized protein OS=Takifugu rubripes GN=LOC101067536 PE=4 SV=1
----TLSNIKTSSERRKEKSRDAARCRRSKETEVFYDLAHQLPLPHSVSAHLDKASIMRLAISFLRTRKLLDT------SNCDEDKEMDSLYLKSLEGFV
AVVTSDGDMIYLSENINKFMGLTQVDLTGHSIFDFTHPCDHEEIRENLSLKTGRGAEQRLLHEDEVHGDHQG-AHSQPQVSRLEQSCW-----ILNLKMY
NSCPPRGLCSFREPPLTCAVLMCEPIPHPSNIDTPMDTRTFLSRHSMDMKFTYCDERVTELMGYTPEDLLGRSVYDFYHALDSDKVTKSHQNLCTKGQAV
TAQYRMLAKNGGFIWVETQGTVIYNSRNSQPQCIVCINYVLSDIEEKSTIFSLEQIEALFKPRHMSG---------------------------------
--FLTEGVVAEPGDALFTKLKEEPEDLTQLAPTPGDTIITLDFARP-----QFEETRGYGQVSAA----GMALPDVPSWSNESLKPAPAAKGPAAFQHPR
TGATSLSSCSTPSSPGDYYSSVDS----DLKVELTEKLLILDTEGNGPANTMDLSDLDLETLAPYIPMDGDFELNIE-PLEGSM-GSNASPTGMMAHQNP
PYRAPARTPLSSMGGRQNLQWPP-----------------------------------
>tr|T1Q071|T1Q071_SCHPR Hypoxia-inducible factor 2 alpha subunit OS=Schizothorax prenanti PE=2 SV=1
----KKEKTRCCSNRLKEKSQNAPRSRPIKETEVFYKLARHLPLPHSISSHLDKASIMRLAISYLRTRKLLTSACATATETTDVDRLMDSWYLKSLGGFI
SVVTSDGDMIFLSENINKLMGLTQVELTGHSIFDFTHPCDHEEIRENLSLKAGMKKGKELSTERDFFMRMKCTVTNRGRTVNLKSASWKVLHCTGHLKVY
NGCPARVLCGFKEPPLACVVLWCEPIAHPSNIDTPLDSKTFLSRHSMDMKFTYCDDRVTELMGYSPEDLLGRSAYEFYHALDSDNVTKSHQNLCTKGQAV
SGQYRMLAKNGGYVWVETQGTVIYNSRNSQPQCIVCVNYVLSDVEEKSMIFSMDQTESLFKAQHLNR---------------------------------
--FFSPSLGSEPGEVLFTKLKEEPEDLTQLAPTPGDTIISLDFGNP-----QYEEHPMYSKVS--------AVAPAVSHSGHDGHKTSYA---TTFQAPP
ASTTSLSSCSTPSSPGDYFTSVDS----DLKVELTEKLFSLDTQEKTSCNQTDLSDLDLETLAPYIPMDGDFQLNIC-QELG------TS-SSR-GPQMP
PYHDPASTPLSSMGGRQNLQWPP-----------------------------------
>tr|Q2ESI0|Q2ESI0_MICUN Hypoxia-inducible factor 2 alpha OS=Micropogonias undulatus PE=2 SV=1
----EKEKKRSSSERRKEKSRDAARCRRSKETEVFYDLAHQLPLPHSVSSHLDKASIMRLAISFLRTRKLIATGCSSCSDGGDEDRQMDSLYLKSLEGFV
TVVTSDGDMIFLSENINKFMGLTQVDLTGHSIFDFTHPCDHEEIRENLSLKTGFKKGKELSTERDFFMRMKCTVTNRGRTVNLKSASWKVLHCTGQLKMY
DSCPPRGLCGFKEPPLTCAVLMCEPIPHPSNIDTPMDSKTFLSRHSMDMKFTYCDERVTELMGYTPEDLLGRSIYDFYHALDSDSVTKSHHNLCTKGQAV
SGQYRMLAKNGGFVWVETQGTVIYNSRNSQPQCIVCINYVLSDIEEKSMIFSLEQTESLFKPRHMSS---------------------------------
--FFTAGVTGEPGDALFTKLKEEPEDLAQLAPTPGDTIISLDFGRP-----QFEEPQGYTQVSAT----AMPPPGPPSWASESHKTASPAKAPSTFQNPP
TGPTSLSSCSTPSSPGDYYSSVES----DLKVELTEKLFALDTEGNSPANTRDLSDLDLETLAPYIPMDGDFQLNII-PEAGSM-GSNAS--SMMGHQNP
PYQAPASTPLSSMGGRQNLQWPP-----------------------------------
>tr|D7R4L4|D7R4L4_9TELE Hypoxia-inducible factor 2 alpha OS=Callionymus valenciennei GN=HIF-2a PE=2 SV=1
----EKDKKRNSSERRKEKSRDAARCRRSKETEVFYELAQQLPLPESISLHLDKASIMRLAISFLRTRKLVAMET----DGKEDAEDLDSLYLGSLEGFI
TVVTADGDMIFLSENINKFLGLTQVDLTGHSIFDFTHPCDHEEIRENLNLKMGFKQGKEPNTDRDFFMRMKCTMTNRGRTVNLKSASWKVLHCTGHLKTY
NRLS-QVLRGPSEPPLTCAVLMCEPIPHPTNIEMPLESKTFLSRHSMDMKFTYCDDSVTELMGYSPEDLIGRSVYDFYHALDSDNVTKSHQNLCMKGQAV
SRQYRMLAKTGGYVWMETQGTVIYNNRNSQPQCIVCVNYVLSDVEEKSSVLSLEQTKSLYQPDHVGG---------------------------------
--FFGAG----AGDTLYTKLKEEPEDLTQLAPTPGDTIISLDFGHP-----SFEESWDFAQVS----------MPPPAWTSESNKPVPRP---SIFQKPM
PCATSLSSCSTPSSPGDYYCNVEN----DLKGELSEKLFALDTES----SSFDLSGLDLETLAPYIPMDGDFQLSII-PEPKSM-EPSAKSTGMMTHQNL
PYQAPASTPLSSMGGRQNLQWPP-----------------------------------
>tr|G3PBW9|G3PBW9_GASAC Uncharacterized protein (Fragment) OS=Gasterosteus aculeatus PE=4 SV=1
----TVPRRRSSSERRKEKSRD-ARSRRSKETEVFYELAHQLPLPRQ-APHLDKASIMRLAISFLRTRKVIATGKSACSRDGEDDQQMDSLYLKSLEGFV
TMVTSDGDMIFLSENISKFMGLTQVDLTGHSIFDFTHPCDHEEIRENLSLKSGSKKGKDLSTERDFFMRMKCTVTNRGRTVNLKSASWKVLHCTGHLKMY
SSCPPRVLCGFSEPPLTCAVLMCEPVAHPSNIDAPLDSKTFLSRHGMDMKFTYCDESVTQLMGYAPEDLLGRSAYDFYHALDSDGVTKSHHNLCSKGQAV
SGQYRMLAKNGGYVWVETQGTVIYNSRNSQPQCIVCINYVLSDIEEKSMVLSLKQTESMFKPQGMSS---------------------------------
--FFTAGAAGEPGDALFAKLKEEPEELTQLAPTPGDTIVSLDFDRP-----PFEEPPGYPQVPPA----AASLPGTASWVSEISRPGPPA---NAFQNPP
PGATSLSSCSTPSSPGDYYSPVES----DLKVELTEKLFSLDTDESTPANTCDLSDLDLETLAPYIPMDGDFQLHIV-PEAGSG-GPAAS--CLLGHQNV
PA--AASTPLSSMGGRQNLLWPP-----------------------------------
>tr|V9P1Z1|V9P1Z1_CLABA Hypoxia induced factor 2 alpha OS=Clarias batrachus GN=HIF-2 alpha PE=2 SV=1
----EKDKKRSTTERRKEKSRDAARCRRSKETEVFYELAHELPLPHSISSHLDKASIMRLAISFLRTCKLLTSGCNTS--ETDIERQLDSLYLKSLEGFI
SVVTSDGDMIFLSENINKFMGLTQVELIGHSIFDFTHPCDHDEIRENLSLKTGANKGKELTTERDFFMRMKCTVTSRGRTVNLKSASWKVLHCTGHLKMY
NSCPTRTLCGLKESPLTCVVMLCEPVPHPSNIDTPFDSKTFLSRHSMDMKFTYCDERVTELIGYNPDDLLGRSVYEFYHALDSESVTRSHQNLCTKGQAV
SGQYRMLAKYGGFVWMETQGTVIYSSRNSQPQCIVCVNYVLSDIEEKSTVFSKDQTESLLKT-HMSS---------------------------------
--FFSQTIDPE---NRLIKFKEEPEDLTHLAPTPGDGVIPLDFGRP-----SFEEFPVYSKVS--------PVHPSANHSVTDGH--------ANFQASP
ASATVLSSCSLLNSPDEYKGPVD-----DLKMEITEKLFAMDTQGNSYN-QTDLSDLDLETLAPYIPMDGDFQLNIC-QEHG------AP-HA--SPPLA
HYTNPASTPLSSVGGHHSLHWPP-----------------------------------
>tr|A0MNY9|A0MNY9_ICTPU HIF 2 alpha OS=Ictalurus punctatus PE=2 SV=1
----EKDKKRSTSERRKEKSRDAARCRRSKETEVFYELAHQLPLPHSVSSHLDKASIMRLAISFLRTCKLFTSGCSTS--ETDIDRQMDSLYLKSLEGFI
SVVTSDGDIIFLSENINKFMGLTQVELIGHSIFDFTHPCDHEEIRENLSMKTGVKKGKDLSTERDFFMRMKCTVTSRGRTVNLKSASWKVLHCTGHLKVY
NGCSTRTPCGYKESPLTCVVMLCEPVPHPSNIDTPFDSKTFLSRHSMDMKFTYCDERVTQLMGYNPEDLLGRSVYEFYHALDSESVTRSHQNLCTKGQAV
SGHYRMLAKHGGFVWVETQGTVIYSSRNSQPQCIVCVNYVLSDIEEKSTIFSKDQTESLLKT-NMSS---------------------------------
--FFSKAMASETSSALFTKFKEEPEDLNHLAPTPGDGFIPLNFGHP-----SFEEYPVCSKVS--------PMHPPATHSVTERH--------ANFQAPP
PSATSISNCSTPSSPDDYKSPVD-----DLKMEITEKLFAMDTQATLFCSFTELSDLDLETLAPYIPMDGDFQLNIG-QELG------AP-HA--SHPLA
HHTNPESIPLASMGGHQSLQWPP-----------------------------------
>tr|W5JXH2|W5JXH2_ASTMX Uncharacterized protein OS=Astyanax mexicanus PE=4 SV=1
----VMSVFRHPSERRKEKSRDAARCRRSKETEVFYELAHQLPLPHSVRSHLDKASIMRLTISFLRTRKLLASGCMGR--QPKEDMQMDALYLKSLQGFV
VVVTSEGDMIFLSENVSKFMGLTQVELTGHSIFDFTHPCDHEEIRENLSIKAGFQHLLDSFAFRSFIQRLRPTANENPKNQCLRKFKYYVLHCTGHLKVY
TRCPPHVLCGFTEPPLTCVVMLCEPITNPSNVDTPLDSKTFMSRHNMDMKFIYCDERVRSLMGYRPEDLVGRSAYDFYHALDSDSMTKSHQNQILSIQSC
NSKFRILTTLLSFVWRNEQGILIYNVENVKRQKIQCLF--FSEIEEKTIVFSMDQTEALFKSHDGAGE--------------------------------
--LFC--SVSDPGSLLFTKLKEEPEELAQLAPMPGDAIIALDFGRP-----QFEEQSIFYKYPC-------QTTGSKLWKMDSPASSSDS--G----LPT
LSSMSISSCSTESSGGDFYGTGEN----ELKVELTERLFAQTTESNSPTDTFDLNDLDLETLAPYIPMDGDFQLNIG-QESL------TP--CYPNPILP
PYQSPATTPLPSRGGRQNLQWPP-----------------------------------
>tr|H2ZZT4|H2ZZT4_LATCH Uncharacterized protein OS=Latimeria chalumnae GN=EPAS1 PE=4 SV=1
----EKEKKRSSSERRKEKSRDAARCRRSKETEVFYELAHQLPLPHNISSHLDKASIMRLTISFLRIHKLLSSACPDDET--ETDNQMDNFYLKSLEGFI
AVVTQDGDMIFLSENINKYMGLTQVELTGHSIFDYTHPCDHEEIRENLSLKTGFKKNKDINTERDFFMRMKCTVTNRGRTVNLKSATWKVLRCTGHIKVY
NACHPH-MCGYKEPLLTCLIMMCQPIPHPSNIDIPLDSKTFLSRHSMDMKFTYCDERITELVGYHPEELLGHSAYEFYHALDSENMTKSHQNLCAKGQAI
SGQYRMLAKHGGYVWLETQGTVIYNTRNSQPQCIVCVNFVLSKIEDNDVVFSMDQTESLFKPHLMNS---------------------------------
--IFSNSLMPEKGELLFTKLKEEPEELAQLAPTPGDAIISLEFGSQ-----KFEEASLYNKGV--------MPPPNKLWPAEAENR--SS---STFQVP-
SGSTSNSNCSMPSSPGDYYTSRDN----NLKVELIEKLFAMDTESKSPCNTADFNELDLETLAPYIPMDGDFQLNIC-QDQN------AP-ANRGKNALS
PYHAPASIPLSPMGCQPDIQWPP-----------------------------------
>tr|M1ES67|M1ES67_MUSPF Endothelial PAS domain protein 1 (Fragment) OS=Mustela putorius furo PE=2 SV=1
----------SSSERRKEKSRDAARCRRSKETEVFYELAHELPLPHSVSSHLDKASIMRLAISFLRTHKLLSSVCSESESEPEANQQMDNLYLKALEGFI
AVVTQDGDMIFLSENISKFMGLTQVELTGHSIFDFTHPCDHEEIRENLSLKSGFKKSKDTSTERDFFMRMKCTVTSRGRTVNLKSATWKVLHCTGQVKVY
SSCPPHGLCSYKEPLLSCLILMCEPIQHPSHMDIPLDSKTFLSRHSMDMKFTYCDDRITELVGYHPEELLGRSAYEFYHALDSENMTKSHQNLCTKGQVV
SGQYRMLAKHGGYVWLETQGTVIYNPRNLQPQCIMCVNYVLSEIEKNDVVFSMDQTESLFKPHLMNS---------------------------------
--IFDSSAVSDKSNCLFTKLKEEPEELAQLAPTAGDVIVSLDFESQ-----SFQGSSSYSNTL--------LP-PSQPWPREPRSH--ST---PAFQVAA
SGATSSSSCSTPSSPGDYYTSLSD----DLKIEVIEKLFTMDTEAKDQGSSTDFSELDLETLAPYIPMDGDFQLSIY-PEQA------TP-GEGGSKSLP
PCCGQTSTPLSSMGGRSNTQWPP-----------------------------------
>tr|F7EH03|F7EH03_MACMU Uncharacterized protein (Fragment) OS=Macaca mulatta GN=EPAS1 PE=4 SV=1
---------RSSSERRKEKSRDAARCRRSKETEVFYELAHELPLPHSVSSHLDKASIMRLAISFLRTHKLLSSVCSENESEAEADQQMDNLYLKALEGFI
AVVTQDGDMIFLSENISKFMGLTQVELTGHSIFDFTHPCDHEEIRENLSLKNGNVYFLLAPTGWESASPLSTSIREIA-HGLAMQEKWIVLHCTGQVKVY
NNCPPHSLCGYKEPLLSCLIIMCEPIQHPSHMDIPLDSKTFLSRHSMDMKFTYCDDRITELIGYHPEELLGRSAYEFYHALDSENMTKSHQNLCTKGQVV
SGQYRMLAKHGGYVWLETQGTVIYNPRNLQPQCIMCVNYVLSEIEKNDVVFSMDQTESLFKPHLMNS---------------------------------
--IFDSSAVSEKSNFLFTKLKEEPEELAQLAPTPGDAIISLDFGNQ-----NFEESSAYGKAI--------LP-PSQPWATELRSH--ST---PAFQAAA
PGTTSSSSCSTPNSPEDYYTSLDN----DLKIEVIEKLFAMDTEAKDQCSTTDFNELDLETLAPYIPMDGDFQLSIC-PEQS------TP-EEAGSKSLP
PCCGQASTPLSSMGGRSNTQWPP-----------------------------------
>tr|H3CWX0|H3CWX0_TETNG Uncharacterized protein OS=Tetraodon nigroviridis PE=4 SV=1
-------------------------------------------------------------------------------SNCDKDRQMDSLYLKSLEGFI
AVVTSDGDMIYLSENINKFMGLTQVDLTGHSIFDFTHPCDHEEIRENLSLRTGFKKGKEMSAERDFFMRMKCTVTTRGRTVNLKSASWKVLHCTGQLKMY
NGCPPRGLCGFREPPLTCAVLMCEPIPHPSNIDTPMDSRTFLSRHSMDMKFTYCDERVTELMGYTPEDLLGRSVYDFYHALDSENVTKSHQNLCTKGQAV
TAQYRMLAKNGGYVWVETQGTVIYNSRNSQPQCIVCINYILSDVEEKSTIFSLEQIESLFKPRHASR---------------------------------
--FLTEAVAAEPGDTLFTKFKEEPEDLTQLAPTPGDTIITLDFGRP-----QFEETRGYSQVSAA----GMALPDAPSWSHESLKPAPAAKTTATFQHPR
AGATSLSSCSTPSSPGDYYSPVDS----DLKVELTEKLFTLDTEGNSPANTMDLSDLDLETLAPYIPMDGDFQLNIE-PLEGSV-DSNTSPTGMIVHQNP
PYRAPASTPLSSMGGRQNLQWPP-----------------------------------
>tr|A0A091CM14|A0A091CM14_FUKDA Endothelial PAS domain-containing protein 1 OS=Fukomys damarensis GN=H920_20123 PE=4 SV=1
----DKEKKRSSSERRKEKSRDAARCRRSKETEVFYELAHELPLPHSVSSHLDKASIMRLAISFLRTHKLLSSVCSENESEVEADQQMDNLYLKALEGFI
AVVTQDGDMIFLSENISKFMGLTQVELTGHSIFDFTHPCDHEEIRENLTLKNGFKKVKEMSTERDFFMRMKCTVTNRGRTVNLKSATWKVLHCTGQVKVY
NSCPPHSLCGYKEPLLSCLIIMCEPIQHPSHMDIPLDSKTFLSRHSMDMKFTYCDDRITELIGYHPEELLGRSAYEFYHALDSENMTKSHQNLCTKGQVV
SGQYRMLAKHGGYVWLETQGTIIYNPRNLQPQCIMCVNYVLSEIEKNDVVFSMDQTESLFKPHVMNS---------------------------------
--IFENSAASEKSNFLFTKLKEEPEELAQLAPTPGDAIISLDFGNQ-----SFKESSAFGKAI--------LP-PGQPWAAEVRNH--TA---PAFQVAA
PGSTSSSSCSTPSSPGDYYTSLGD----DLKIEVIEKLFAMDTEAKDQCSTTDFNELDLETLAPYIPMDGDFQLSIC-PEQP------TP-EEAGSKSLP
SCCGQASIPLSSMGGRSNTQWPP-----------------------------------
>tr|A0A0B6YT30|A0A0B6YT30_9EUPU Uncharacterized protein OS=Arion vulgaris GN=ORF35837 PE=4 SV=1
-----AKDKRRNTEKRKEKSRDAARCRRGKETEVFMELANCLPVPESVFSQLDKASIMRISISMLKIFNILQSDSNND---SAKIDKFDHLYQKALEGFA
FILAQEGDIVYLSESVARYLGLQQIELVGQSVFDFTHPCDHDEIKEVLAIKQQQQLI--SSDTRNFFMRMKCTLTAKGRNANLKSATYKVLKCTGRVITK
KGSGSQDQCQ-VQTTLHYLVGIAEPIPHPVNIEVPLDSKTFLSKHSMDMHFIFCDERIKELAGYDCEGMIGQSLYDFHHALDSEVIDKAFKDLFSKGQTV
TGSYRFLARHGGYIWVVTQATIINNSRSQKPQWVVCVHYVLSGIEDNGTILSHIQCPDLLNTKVELN------------TENIFAPKTKDM---EQ----
G-YMKPE---IKGSI--MFHDKDPEDLSYLAPNAGDELIPLTFNIL----------------LSPS--H-----ALKQEPGTSTPDMCYRKDA------S
PAALSSNSSSRIASPNDYMSM--A-----VDVESMDKFFQIKTS---E-EDGDAEDIDFDMRAPYIPMDGDLGLLPP-----------------------
----------------------------------------------------------
>tr|M1K779|M1K779_HALDV Hypoxia inducible factor-1alpha OS=Haliotis diversicolor PE=2 SV=1
-----SKDKKRNSDKRKEKSRDAARCRRSKETEVFYELAQNLPLPSSVSTQLDKASIMRLTISFLKICKIREEKKWHD---DDIQKRLHQMYPKALEGFV
LILSREADIVYLSENTAKFLGIQQIELMGQSIFDFTHPCDHEEIRDMMSDRPGSK-A--VSEERTLFIRMKCTLTSKGKSVNLKSATYKVIKCTGRLVVA
KKSKKD--SD-DASMYPYLLAVGEPIPHPANIEAPLDSSTFLSKHNMNMSFTYCDDRIQDLIGYNNDNLIGKSLYNYHHALDSEIVEKAFKDLFAKGQTM
TGQYRFLAKNGGYAWVITQGTIIYNNRTQKPQWVVCVHYVLSAIQEKNMILSEVQQQDLLSFKMEQS------------TDKIFGPRTKDM---EQ----
N-YFVPE---LKNNI--TLVNNEPADLSYLAPTAGDGCVQLGFPDF----------------ACMD--KDLPPPMCKEEPDPVPRDVHRNQEF------N
SNPSPASLSPRIQSPDEYQTIASP-----TDVDLMDKFFSMDTTQKGS-SDSDMEDVDLNMRAPYIPMNADFSLVPP-----------------------
----------------------------------------------------------
>tr|A0A0P6DJR3|A0A0P6DJR3_9CRUS Hypoxia-inducible factor 1-alpha OS=Daphnia magna PE=4 SV=1
-----RFRSIRNSEKRKEKSREAARCRRSKESEIFTDMANLLPVPASLSSQLDKASIMRLTIAFLKAQSLLGNSVQELCWNEEKCSMADACWPQALGGLL
LALSSEGDIIYLTENVTQQLGLPQMDLIGQSIYDYCHPCDHDELREVLSLRP------DGDLTRSFFLRLKSTITAKGRSNNLKAASYKVMNCSGRIVLA
TASARNLELEAKAPTSHFLVMVGDPIPHPSNIEMPLDSYTFLTKHTLDMKYTYVDEKIYEFLGYTSEDLEGQSAYQLHHAQDNESILKSYKTMFTKGQIQ
TPPYRFLARHGGYAWVQTQATLVYGNRDSRPQAVVCVHTCLSEIEDGDQILFASQAESSPI--------SLAHRPLAAA----PGPSRKPPTDWVPQNMT
SKLFVPKTAENEGFLIFDVLKEEPEDLTHLAPVAGDTCIPLDMPSISFDIFDVELTPEFFDC-LPLTGFDIPLMESEQWIASDGSGAMEQEDPFIFFNST
P---LPSSSSNMSSPMASSSQGNEDYEIDYRIDVASETFMACSSLKSSKS-PLEDEDELDRRAPYISMNESDDLPLFDPSELFS----------------
----------------------------------------------------------
>tr|E9G615|E9G615_DAPPU Putative hypoxia inducible factor-1 alpha OS=Daphnia pulex GN=DAPPUDRAFT_347564 PE=4 SV=1
-----PKEKRRNSEKRKEKSREAARCRRSKESEIFTDMANLLPVPSSLSSQLDKASIMRLTIAFLKAQSLLGNSVQELCWNDDKCSMADACWPQALGGML
LALSSEGDIIYLTENVTQQLGLPQVDLIGQSIYDYCHPCDHDELREVLSLRP------DGELARSFFLRLKSTLTAKGRSNNLKAASYKVMNCSGRIVLA
TASVRNLEVEVKSPTSHFLVMVGDPIPHPSNIEMPLDSYTFLTKHTLDMKYTYVDEKIYEFLGYMPEDLEGHSAYQLHHAQDNESILKSYKTMFTKGQIQ
TPPYRFLARHGGYAWVQTQATLVYGNRDSRPQAVVCVHTCLSEIEDGDQILFVSQAEASAT--------GLVQRPLAAA----PAPSRKMPNEWLPQNMT
SKLFVPKTAEDEGFLIFDILKEDPEDLTHLAPVAGDSCIPLDMPSIAFDLFDVELTPEFFDC-LPLTGFDIPLIEPEELIEDDDNGAIEKEDPFIFFDAS
P---LVNSSSNLSSPVPSISSVKGDYDKEFPIESPIETFMGGCSVQSSIS-PIEDEEELDRRAPYISMNGSDDLPLFDPSELFS----------------
----------------------------------------------------------