>seq_1
MSDLMQKENIVVMLTKKGFLKRLSQNEYKLQGTGGKGLSSFDLNDGDEIVIALCVNTHDYLFMISNEGKLYLINAYEIKDSSRASKGQNISELINLGDQE
EILTIKNSKDLTDDAYLLLTTASGKIARFESTDFKAVKSRGVIVIKLNDKDFVTSAEIVFKDEKVICLSKKGSAFIFNSRDVRLTNRGTQGVCGMKLKEG
DLFVKVLSVKENPYLLIVSENGYGKRLNMSKISELKRGATGYTSYKKSDKKAGSVVDAIAVSEDDEILLVSKRSKALRTVAGKVSEQGKDARGIQVLFLD
NDSLVSVSKFIK
>tr|X0S1X1|X0S1X1_9ZZZZ Uncharacterized protein (Fragment) OS=marine sediment metagenome GN=S01H1_00767 PE=4 SV=1
-EDLIKKEEIVVTTTRHGYIKYTSLRAYKRQRRGGKGMSGMITGKEDFVEDLFITHTHSILLFFTNLGKVHWARAYDIPQKKRSAKGRALVNFLSLGKNE
RVSKTLPLDNFDQEGFLVMVTRKGKVKKTSLSAYSHPKKGGIRGIRLKEEDELIKVLPTQGEEDIVLVTRKGKAILFSEKDVRPTGRTSLGVKGISLGEE
DEVMDAVIAKEDEALLTITSKGYGKRTLFAKYRKTRRGGKGIINLRFVP-DKGEVVGAKRIKPSDEVIVITRKGKSIRLAAKNISLIGRNTSGPRIIRLG
QDEVIAL-----
>tr|X1FIU2|X1FIU2_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=S03H2_01492 PE=4 SV=1
-EDLIPKEETIITLTQGGYIKRLNPATYKIQKRGGKGILGMKTVGEDIVEHFLTANTHDSLLLFTDSGKVFRTPVYEIPEGTRVAKGRGLLNFLEISSEE
KVLSLMPLSKKQFAKYLVIVTKDGIIKKTALEEFENVRKSGLIAINLKKGDLLRRVRKTTGQDEIILVTKKGQSIRFKEKEIRPMGRSAAGIRGIRLKRG
DEVIGMDIVDVKEYLLVVMKNGFGKRTDLREYRLQGRGGSGIKTAQVTS-KTGNLVASKVLTTEEDLIVISQKGQVIRAAISGIPKLSRVTQGVRIMRLG
EGQVASA-----
>tr|A0A0G0FJB1|A0A0G0FJB1_9BACT Gyrase subunit A protein OS=candidate division WS6 bacterium GW2011_GWF1_36_8 GN=US29_C0003G0020 PE=4 SV=1
-EDMVASEDMLVTITHTGYIKRLTPDTYKAQKRGGKGVSGGDTKEGDFIEHAFLCNTHDELLLFTNKGKVFNLRIFEIPEYGRTAKGLPLVNLVQLEPEE
IITSVLTRDPKTAYKYFLMVTEKGIIKKTELSEFAKIRANGLTAIKLENGDQLAWVKPTTGEDEVLIVTADGKSVRFKESDVRPMGRNTRGVTAIKFKSA
DCVAGMGIVKN-MMVLTLSENGFGKMSVLKEYPTQKRGGTGVFTFRVTP-KTGKISTARIIEPQEEIVVISEKSKVIRSELKTVPKLGRQTSGVKIMNIG
SDRVATV-----
>tr|A0A0E9DEC0|A0A0E9DEC0_CHLTH DNA gyrase subunit A OS=Chlamydia trachomatis GN=gyrA_3 PE=4 SV=1
---MIPRKDVVITVTTNGYLKRLDLDEYKEQGRGGVGVSTAKTYQDDDIQDILVANTHTDLLIFTTDARVYRVRGYEVPIGTKQSKGVPIVNIIGLGKDE
KVVKILSVDDS-KEKFLITATKKGIIKKSSLSLYKLINKNGKLAFGLKEGDTLVDALVATNSEEIYIAANNSKMCRFDIADINSMGRIAAGVIGIKLSDN
EKVVSVSTSSE-KYIFSLGANGFGKLSPVDTFRKTRRNSKGVLALNE-D-KAGELAYSAAVKGTEDIIVITDEGVSIRFSLKQVSITGRNTKGVKLINLK
KRSIVGV-----
>tr|A0A0G0PV75|A0A0G0PV75_9BACT Gyrase subunit A protein OS=Microgenomates (Woesebacteria) bacterium GW2011_GWA1_39_8 GN=UT61_C0037G0009 PE=4 SV=1
-EDLIPKEETLITLTKTGYVKRVPRTTYRAQRRGGKGVTGMTTKEEDEIEQIIAATTHDMLLFFTNTGKVFGTKVWEIPESSRQSKGQAVVNLIQIDQNE
KIMSILPLSA----KNILMATEKGIVKKTPTSEYKNLRASGLIAIRLDPDDSLMGVHQTSGDDHVLLVSRNGKAIRFPEANTRPMGRATSGMRGIKLESG
DAVIGMEIFPGFKDILTISENGLGKRTPIHLFPVQKRAGKGVKASVVNA-KTGKLTAASMVTNTDQIVITSKTGQVIKLPLKNIPHLGRATQGVILMRFA
KKAVAAV-----
>tr|A0A0G1JXZ4|A0A0G1JXZ4_9BACT Gyrase subunit A protein OS=Microgenomates bacterium GW2011_GWA2_44_7 GN=UW69_C0003G0009 PE=4 SV=1
-EDLVPLEETIITITGTGYIKRQNPSVFKAQHRGGKGVMGMETKEEDEIAHLVAGTTHDDLFFLTSKGRIFKVKTWELPEGSRQSKGQALVNLINTEQDE
TVQSVLAINPKH-QKYLLLVTRKGTVKKSAIADYENIRTSGLIAIKLEAGDELVWARTTSGEDDILLATHEGKSIKFKEKDVRPTGRDTMGVRGILLGKE
DYVIGMESFPPFRDILVVMEKGIGKRTPIGQFPVQNRGGQGVKVAQVTP-KTGKVVALQMVDQYDEVVLTSRNAQVIKLPLRNIPELSRATQGVILMRFQ
SKSVAAV-----
>tr|A0A0G1YGS9|A0A0G1YGS9_9BACT Gyrase subunit A protein (Fragment) OS=Parcubacteria bacterium GW2011_GWA2_50_10b GN=UY54_C0022G0001 PE=4 SV=1
-EDLVPEEEQALVLTSGGYIKRTNPDEYKRQKRGGVGVIDLDTKEEDFVTQFLSASTHADLLFFTDKGKAYQIKMYDLPEGKRATKGKSVMNFISLSDDE
KVTSILPMPKGESASSLFMVTEQGTAKKVSAKSFADVRSSGIIAIRLSAGRRLVSVELVEKADDISIVTKKGQSIRFKNSLVREMGRSAGGVRGIKLEKG
DTVVGAHVVKPSGHLLVISAAGYGKRTKLTEYKVQGRGGSGILTSKVTP-KTGVVIASQVVTDEEEVIAISKKSQVVRVGLQEIPVLGRQTQGVRIMKLR
EGSLASL-----
>tr|A0A0G1YQ84|A0A0G1YQ84_9BACT Gyrase subunit A protein (Fragment) OS=Parcubacteria (Kaiserbacteria) bacterium GW2011_GWA2_58_9 GN=UY98_C0042G0001 PE=4 SV=1
-EDLVADEDSVLVLTQGGYIKRTNPNEYRRQKRGGVGVVDLDTKEEDFVTQFLTASAHSDLLFFSDRGKAYQLKMYELPEGKRATKGKSIMNFLSLEQGE
NITSILAMPKEKEGLALVMATKRGTVKKVAADKFHEVRRSGLIAINLEKGDALISAAFVRKGDSVVLVTAKGQSIRFDEKSVREMGRQAAGVRGMKLGAG
DGIVGTGVVPKSGELLVLSSTGYGKRTKLGEYKVQGRGGSGIKTMSITA-KTKQLVGAAVLLGEGELVAMSKKSQTIRTGLEGIPTLSRATQGVRVMKLR
EGSVASF-----
>tr|A0A0G0RB88|A0A0G0RB88_9BACT Gyrase subunit A protein (Fragment) OS=Parcubacteria bacterium GW2011_GWC1_40_13 GN=UT80_C0011G0017 PE=4 SV=1
-EDLIPDEETVLVLTTGGYIKRTNPDEYKKQKRGGVGVVDLDTKDEDFVTTFLTATMHSDVLFFTDKGKAYQVKMYELPEGKRATKGKSIMNFLSIGAEE
KVTSVLPMPKEKLKLSLLMITKKGVAKRVDAEAFHDVRRSGLLAITLQDGDELKIVSFTAPGDEAIIATSKGQSIRFKESDIRVMGRGATGVRAIRLGKG
DSVVGADVIKKSPAFLVISQNGYGKKTDLKEYKTQNRGGSGIRTMKVTP-KTGDIIASKIITEDQEVVAISKKSQVIRVDSKEIPSLGRQTQGVRIMKLK
EGSLVSL-----
>tr|A0A0G0ZXL2|A0A0G0ZXL2_9BACT Gyrase subunit A protein (Fragment) OS=Parcubacteria bacterium GW2011_GWA2_42_28 GN=UV19_C0012G0001 PE=4 SV=1
-EDVIPNEQAIIVLTRDGYIKRLPPDTFKQQHRGGKGVMGLATKEEDVVEDLLVAMTHSDLLFFTTRGRVFKLKVYDVPQTSRTAKGMAIVNFLELGPSE
KVSSILSLADL-DYKYLAMVTKSGTIKKVDIQDFESVRRSGLIAIKLRDEDALEWVKPSKGKEEMVLVSSKGQAIRFKETDVRGMGRVASGVRGMRLGRG
DSVVSLGIVDSMLELLVVGKNGYGKRTNMKNFKVQHRGGSGIKAGKVTP-KTGEIVYAQVSESERDLIVISEKGQVIRLAFGDIPVLGRATQGVRIMSFK
EGSVASV-----
>tr|X1KK03|X1KK03_9ZZZZ Uncharacterized protein (Fragment) OS=marine sediment metagenome GN=S06H3_06632 PE=4 SV=1
------HQRVVVTLSNRGFVKRVPSHLYTLQHRGGKGIKGMETRENDAVRLLVVADTHDSLLFFTNRGKVFCLKCYEIPAGSRTAKGMAVINLFPIAEGE
RVTDVVSVADF-QDAYLLMATRLGEIKKTALDKFASVRSSGLIAMDVEKGDELVAARLATDKDDVMMITQKGQSIRFAVSGVRASLRTSGGVCGIRLGSD
DQAVSMEVASP--FLLVVTANGFGKLTPISGYPRQKRAGSGVRTFKLTE-KTDEVVAAKLTSLSQQVMIISADGIVIRTPAKGITIQGRSTQGVKLMKLA
EGRVVAI-----
>tr|X1GJD8|X1GJD8_9ZZZZ Uncharacterized protein (Fragment) OS=marine sediment metagenome GN=S03H2_32623 PE=4 SV=1
------------------FIKRVPSRAYRPQHRGGRGIIGVVTREADAVRLLAVADTHDNLLFFTNRGKVFRLKCYEIPPDSRTAKGIAVVNLFPVTDDE
RITALVAVTDF-PNTYMLLATRGGEIKKTALDKFASVRSSGLIAVNLETGDELVAACLATDQDDVILVTQRGQSIRFAVSELRATSRTSGGVCSIRLASD
GQVVGMGIAYP--FLLVVTTGGFGKLTPIDNYPRQHRAGSGVGTFKLTE-GTGDIADARLVSLAQQVMIISANGIVTRTPVKGITIQGRSTQGVRLMRLG
------------
>tr|A0A0G1TG29|A0A0G1TG29_9BACT Gyrase subunit A protein OS=Parcubacteria bacterium GW2011_GWA1_47_8 GN=UY07_C0035G0002 PE=4 SV=1
-EDMIPDEESILVFTKGGYIKRTNPSEYRQQNRGGVGVVDLNTKDEDFITLFLSARTHSDTLFFSDRGKAYQIKMYEIPEGKRATRGKSIMNFISLSGEE
KVTSVLAMPKTKAKMSLFMVTKYGTVKKVSADSFKDVRKSGIIALRLDQGDELLSTLLVGKGDDIILTSAKGQAIRFKESDVREMGRTAGGVRGMKLRTG
DFIVSADLLCKNPELLVMSANGYGKRTPMKEYKIQKRGGSGIKTAKVTP-KIGALIVAKVVTPYKEIVSISKKSQVIRIAIEDVPSLGRDTQGVRIMKLR
EGMIASL-----
>tr|T0YFF3|T0YFF3_9ZZZZ DNA gyrase, A subunit (Fragment) OS=mine drainage metagenome GN=B1A_18847 PE=4 SV=1
-EDLIEDEDLVVTLTQAGYIKAMPVSAFKSQARGGKGVMGTRLKEEDLITSVVYTSSHSYLLLFTNLGRVYRLRGHEIPVKERSARGTAIVNIVSMDPGE
KVAEIVSARE--GDGYLIFVTKQGLVKKTKLEEYDKSRREGIIAITLRPGDELVKVMGTSGNDEIVMFSSYGKGIRFSERDVRSVGRVAAGVIGMRMSQG
DTVVGSDIVSA-SNVLLMTSAGYGKRTGIEQFNTQARGGQGVRAIRTTA-ARGNLAGAFLVDMASEILVVSTGGTVIRVAVADVARQGRDATGVRVM---
------------
>tr|A0A0G0TQV1|A0A0G0TQV1_9BACT Gyrase subunit A protein OS=Parcubacteria (Nomurabacteria) bacterium GW2011_GWA2_40_9 GN=UU24_C0010G0012 PE=4 SV=1
-EDLIPEKETVLVFTSGGYVKRTDPSEYHAQKRGGVGVVDLETKEEDFVTMLVSSSTHSDLLFFTNLGKAYNIKMYDIPEGRRATKGKSIMNFLALSTDE
TVTSILPIPKDTGGESLMLITKDGTAKKMSAESFKDVRRSGIISIKLDKGDSLISALFTSKGDEVMIATDGGQAIRFKESDIREMGRTAGGVRGIKLSKG
DQVIGVDVIKKDGAFLTMSANGFGKKTSLKEYKVQNRGGSGIKTAKVTT-KTGKLIVAKVLGGEEELIAMSKKGQVIRTALKDISALGRQTQGVTIMRLR
AGGIASV-----
>tr|A0A0G1U4P3|A0A0G1U4P3_9BACT Gyrase subunit A protein OS=Microgenomates bacterium GW2011_GWF2_47_9 GN=UY18_C0004G0011 PE=4 SV=1
-EDLVAKEDNLVAITKEGYVKRMPLGTYRSQRRGGKGVMGMTTKDEDEILHLTVGNTHDFALFFTNTGKVFMNRVFELPEGSRQAKGQAIINLINIEQDE
KVMALMTIPGGLKNHFITMVTKKGLVKKTPISEYASIRSGGKIGINLKDNDELVRAQVTNGENYLLLVTRDGKSIKFKESDVNPTGRDTMGVKGIALKKD
DFVIAAETFEIYREILLVTENGIGKRTDVSEYPEQKRGGQGVKVAELTD-KTGKVAAAQMVSEDLQLVMTTKSAQVIKLPMKNIKVLGRSTQGVILMRPT
K-KVTSI-----
>tr|A0A0G1T802|A0A0G1T802_9BACT Gyrase subunit A protein OS=Parcubacteria bacterium GW2011_GWA2_47_7 GN=UY04_C0049G0017 PE=4 SV=1
-EDTIPEKENVIVFSDGGYIKRTDPAEYRTQRRGGVGVMDLDTKEEDFVKMFLTTSTHSDILFFTDKGKAYQIKAYELPEGRRATKGKSIMNYLSLGGDE
SVTSMLVMPREKEELSLVMVTEKGVVKKVAADGFRDVRRSGLIAIKLQAGDQLLTARFVESGDEISLVSQEGQSIRFKHTDVREMGRNAGGVRGINLKGK
DKLVTADVIKKDPLLVVLSEKGYGKMSKLSEYKVQKRGGSGIKTAKVTP-KTGKLMTGLVVSDEGEIVAISKNSQVIRVTLKEVPVLGRQTQGVRIMKLR
EGSIASL-----
>tr|C2KY17|C2KY17_9FIRM DNA gyrase C-terminal domain, beta-propeller OS=Oribacterium sinus F0268 GN=HMPREF6123_1406 PE=4 SV=1
-EDLIADDDVVITSTSLGYIKRMSPENFRQQNRGGKGIKGMQTIEKDYIEDLFMTTNHHYIMFFTNMGRVFRIKGYEIPEASRTARGTALVNLLPLQEGE
KVNASLCLRD--DEQDLILTTKSGMVKKTALSEYANVRRNGLIAISLKEDDQLIEAKLLSKDENIILVTKKGMAIQFNEKDVRRTGRSSMGVIGIRLNDG
DEVIGMQESSQ-ENMLVVSEKGYGKLTEKSAFKAQNRGGKGMRCYKITE-KTGDLVGFKLCDQDREILLITTEGIMIRMSLENISIIGRNASGVKLMNLD
KDDTTIA-----
>tr|M6R4P9|M6R4P9_LEPIR DNA gyrase C-terminal domain, beta-propeller OS=Leptospira interrogans serovar Icterohaemorrhagiae str. Verdun HP GN=LEP1GSC116
-EDLIADEEIVIQITYDQFIKRLPIDTFKRQKRGGKGIQGLSQKRDDVIKIMKAAMTHDNIMFFSNIGKVYVMKAYELPIASKEARGKSLKAIINLREDE
YISSVFTFRG--MDKDLLLVTRKGFIKRIQLKEFGNVKKSGIIAIGLREGDELIKVESMTDKDEVMIFSKKGLALRIEGNIIRAQGRTASGVTGMRLAED
DAIVGLSKYKE-EDIFVVSEEGYGKRLGFEEFAAKGRGGKGMAYLKITE-KNGFSVGTGSVGSEDEIILITQQGMTIRINAFDISKLGRTAVGVRIVDLK
DNKVQDF-----
>tr|R5SYX3|R5SYX3_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:75 GN=BN771_00576 PE=4 SV=1
-EDMIPHENTIITMTKLGYIKRMTVDNFKSQHRGGKGIKGMQTIEDDYIDDMIMTTTHHYIMFFTNTGRVYRIKAYEIPESSRTARGTAIINLLQLMPGE
KITAVIPFKE--EDKYLFMVTKRGIAKKTPILEYFNIRKSGLQAINLRDDDELIEVKITDNKKDIIMVTKHGQCIRFHEKDVRTTGRNSMGVIGMNLSYD
DEVVAMQLNTQ-TQLLLVSEYGMGKCTNIEEFTPQHRGGKGIKCYKITE-KTGNVVAAKAVNSDNEVMLITTEGIIIQIMVDEISILGRITSGVKLIDLD
PNEIVVA-----
>tr|X0RER7|X0RER7_9ZZZZ Uncharacterized protein (Fragment) OS=marine sediment metagenome GN=S01H1_12219 PE=4 SV=1
-KDLVQKKEVVITITEKGYCKRMDVKSYREQRRGGKGVIGSNLATGDFVKQLITCSTHDYLMFFTTRGRVLWLKAYDIPEAERYSKGKAMINLLNLKD-E
KVTSVISVNKF--EYFLFMATRNGVVKRISLAHFSKPRASGVRAINLPADDVLIGVQILERGEEVLLSTKKGKAIRFSSNNVRDMGRASYGVTGIKMGKD
DEVVSLEVLKT-QAILTITKNGYGKRTAVKDYRKTARAGKGVINLKVTQ-KTGNVVTTISVNPTDSIIITTAKGM-------------------------
------------
>tr|T0LML9|T0LML9_9EURY DNA gyrase subunit A (Fragment) OS=Thermoplasmatales archaeon A-plasma GN=AMDU1_APLC00109G0003 PE=4 SV=1
-ADLVPEEDDVVILSEGSLLKRVSLEEYRAQRRGGKGIITST-RKEDSVKTILSCSSHDSIFMFTNTGRVLRTLAYEIEKKSRKSVGVTAASYVPLQEGE
VVEQIMKAPES-RESHLVILTRNGFIKRTPAEAILDMRSSGIRIIALEDDDEVVSVEAISREGNIVAISNSGKASVFTTSEVRPTGRTSRGVRAMKLKKG
EYIITGFIAQDDEEVLTVSENGIGKRTPIAEFSVHHRGSSGILVFKKSE-RTGNLVKAIPVRPDDEIMIITRNEKTIRLKVSGIKSQARVTSGVKLIDTS
DNAVIEV-----
>tr|A0A072EJ16|A0A072EJ16_9STRE DNA gyrase subunit A (Fragment) OS=Streptococcus equi subsp. ruminatorum CECT 5772 GN=CECT5772_08059 PE=4 SV=1
-EDLIEEEDVLITLSNNGYIKRLAQDEFRSQKRGGRGVQGTGVNDDDFVRELVSTSTHDTLLFFTNFGRVYRLKAYEIPEYGRAAKGLPVINLLKLDDGE
TIQTIINAKKEDLDKYFFFTTKQGIVKRTEVSEFSNIRQNGLRALNLKEGDELINVLLTNGQEDIIIGTRSGYSVRFNEATIRGMGRSATGVRGVKLREE
DWVVGASRINDKQEVLVITENGYGKRTSAAEYPTKGRGGKGIKTANITA-KNGQLAGLMTVDGSEDIMVITTKGVIIRTNVSSISQTGRSTLGVKVMRLD
TDKIVTF-----
>tr|A0A0R2B9E9|A0A0R2B9E9_9LACO DNA gyrase, A subunit OS=Lactobacillus coleohominis DSM 14060 GN=FC35_GL000729 PE=4 SV=1
-EDLIEQQDIVVTLTHNGYIKRLPVDEFKSQNRGGRGVKGMGVHSDDFIEHLISSSTHDMLLFFTNSGKVFSMKGYEIPEYGRSAQGIPIINLLGIDAKE
KINAVINVSNTAADRDLFFVTKQGIVKRTAVEEFKNIRSNGLKAINLHDGDELIAVEIIDHDQNMIIGTHEGYAVSFSASAVRSMGRAAAGVRGVRLREG
DFVIGAGQLNPDSRVLVISEKGFGKQTPAAEYPIKGRGGKGIKTVNVTE-KNGPLAGLTTVDGDEDIMLVTTEGVIIRFGVETVSETGRATIGVHLIKLT
DGKVATM-----
>tr|E3R1R4|E3R1R4_9LACO DNA gyrase, A subunit domain protein OS=Lactobacillus crispatus CTV-05 GN=LBKG_00475 PE=4 SV=1
-EDLIEKQNILLTVTHNGYIKRMPIQEFKTQNRGGKGIKGMGVQDGDFIEHLIYSSTHDLLLFFTNAGKVYSKKAYEIPEYGRAAKGLPVVNLLQLEKGE
KVQTVINIPEGADDNYLFFVTKMGTVKRTHVSEFSNIRNSGLIALTLKDGDELSNVLTTDGKQNILIGTHLGYAVTFNEGDVRAMGRTAAGVRGINLREH
DYVVGSGILGADDQVLVISEKGYGKRTPASEYPVKGRGGKGIKTANITE-KNGPLAGVTIINSNNDVMVITTDGIMIRFRIDDVSQTGRSTMGVRLIKVS
DDQVASL-----
>tr|A0A0J6UMQ9|A0A0J6UMQ9_LACRH DNA gyrase subunit A (Fragment) OS=Lactobacillus rhamnosus GN=PZ01_12550 PE=4 SV=1
-EDLIEQEDVVITLSHNGYVKRLATSEFKTQNRGGRGIQGMNVHDDDFVEHLISTSTHDVLLFFTNKGKVYRSKGYEIPEYSRTAKGIPIINLLGVGAGE
KIQTVINVHEGDDDRYLFFVTQNGVVKRTPVKEFANIRSNGLIALNLKDQDELNNVILTSGQDNILIGTHLGYSVAFKEQDVRSMGRTATGVRGIRLRDH
DYVVGSDILKPDSEVFVISEKGYGKRTAAKEYPIKGRGGKGIKTANITE-KNGPLAGVTTVDGTEDILVMTDSGVMIRFNIQNVSQTGRATLGVRLIRVD
DDKVATM-----
>tr|F9P692|F9P692_STRCV DNA topoisomerase (ATP-hydrolyzing) OS=Streptococcus constellatus subsp. pharyngis SK1060 = CCUG 46377 GN=HMPREF1042_0987 PE=4 
-EDLIEEADVLITLSNKGYIKRLNQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHERLLFFTNKGRVYRLKGYEIPEYGRTAKGLPIVNLLKLDEGE
TIQTIINVQAEHDHSYLFFTTRHGVVKRTSVTEFANIRQNGLKALNLKDEDELINVFLTDGQTDIIIGTKMGYAVRFNENQVRNMGRAATGVRGVNLRPD
DHVVGASVISDNQEVLVITEKGYGKRTLASEYATKGRGGKGMKTANITE-KNGPLAGLMAVNGDEDLMIITNTGVIIRTNVANISQTRRATLGVKVMRLD
KGQIVTF-----
>tr|W1VAD1|W1VAD1_STRPA DNA topoisomerase (ATP-hydrolyzing) (Fragment) OS=Streptococcus parasanguinis DORA_23_24 GN=Q616_SPPC01285G0001 PE=4 SV=1
-EDLIEETDVLITLSNKGYIKRLDQAEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRLKGYEIPEYGRTAKGLPIVNLLKLDEGE
SIQTIINVEQDRDEAYLFFTTRQGVVKRTNVAEFSNIRQNGLKALNLRDEDELINVFLTDGNTDVIIGTKYGYSVRFNEAVVRNMGRSATGVRGVNLRDG
DKVVGASVITDQDEVLVITEKGYGKRTMAGEYPTKGRGGKGIKTANITE-KNGPLAGLLTVKGDEDLMIITDTGVMIRTGVANISQTGRSTQGVKVMRLD
QDKIMTF-----
>tr|A5GZV2|A5GZV2_9MOLU DNA gyrase subunit A (Fragment) OS=Acholeplasma multilocale GN=gyrA PE=4 SV=1
-EELIPDVKTMILLSEEGYIRRVDPEEFRIQKRGGRGISVNSSND-DPISIATMGKMRDWVLFFTNSGKVFRTKAYNIRQYSRTSRGLPIVNFLNLTPED
KITAILPMRNE-KFKYLTFVTEAGMIKRTDISLFDSINQNGKIAITLKDDDQLVTVMPTTGEDTVFIANKSGKVIRINEDIVRPLSRTATGVKGIKLDED
DIVVGAVTSYGIEAITTISSKGNFKKTALDEYRISGRNGKGIKVMNLNE-KTGDFKAIIAARETDLILIISSDGNL------------------------
------------
>tr|A0A0F3GWS0|A0A0F3GWS0_9BACT DNA gyrase, A subunit OS=Candidatus Magnetobacterium bavaricum GN=MBAV_001485 PE=4 SV=1
-EDLITEEEMVITVSHNGYIKRNPLSEYRQQRRGGKGMTSMETREEDYVQQLFIGSTHNHILFFSNFGRLYLLKIYQIPEAGRAAKGKAIVNLLQLQPGE
TIATALPIKGF-DKGYLIMFTKKGIVKKTLLREFSNPRGKGVIAINIDEDDELMAVRYADGQSDVLIGTCLGHAIRFNEEDVRSTGRSSRGVKGIRLKKG
DEVVSAEVVEEKTTLLNVTQFGFGKRTNLQDYPLQGRGGQGVKSIKVTE-KGGKVVGLIQVRDEDEIMVVTKSGKSIRTIASAISVTGRNTQGVKLMDVG
KDMIMSI-----
>tr|J9GL05|J9GL05_9ZZZZ DNA gyrase, A subunit (Fragment) OS=gut metagenome GN=EVA_09056 PE=4 SV=1
-EDFYADDEVVITISHLGYIKRTPLADFKAQARGGVGSKGGSTRDEDFIEYIYPATMHNTMLFFTAKGRCFWLKVYEIPEGAKNSKGRAIQNILNIDSDD
CINACLHIRKLGKTHYVLFCTQQGVVKKTCLTEYSRPRTNGVNAISIREDDRVVSVCLTNGDDEIVIANRNGRAIHFHEDKVRTMGRVATGVRGITLDED
DEVVGMVCINDKESILVVSENGFGKRSSIDDYRETNRGGKGVKTLSITE-KTGKVVAVKSVTEDHDLMIINKSGIAIRLKVADVRIMGRATQGVTLINLE
KRDTISS-----
>tr|T0S1E6|T0S1E6_9DELT DNA gyrase C-terminal domain, beta-propeller OS=Bacteriovorax sp. DB6_IX GN=M901_0818 PE=4 SV=1
-EDLVKQEEVIVTITHKGYVKRMPVDTYRTQKRGGKGVKGAA-NDDDFFTNIFTANTHDTLLFFTSRGQVFSKKVYTIPEGTRTSKGRNLANLIAIPGGD
KVTEIICVPKG-NEKYLIFATNKGLVKKSSLEDYSNIKQSGLKAIKLQDGDHIVNVRISDGSKDVLLCSSSGKIIRFAESDARPMGRVSQGVKGINIDET
EKIIGMELIDD-MEILSVTEKGYGKRTQASQYRKQTRGGKGILAMRLTD-KNGEIIQIKPVTDKDDLMVVTDRGQVIRTKISGISLMGRATQGVRILTPK
EDKVVSV-----
>tr|W0FMC5|W0FMC5_9BACT DNA gyrase subunit A OS=uncultured bacterium Contig27 PE=4 SV=1
-EDLIQEENMVVTLTHEGYVKRVSSSVYRAQHRGGRGVSGMNVKETDYTTQMFVVSTHQEIMFFTNLGRVYSLKCYQIPEAGRQARGTAIINLLQISGGE
KVSTMLPMPKE-SEHNLVMATRRGMIKKTALDEFRNLRKNGLIAIALREGDELIGVRLSNGDDEMLVSTRKGKCIRFNERHVRNVGRNSIGVRSMRIAEG
DDVIDIAAVEP-TTVLAITTGGYGKRTDPEEYREQGRGGMGIKAMQLTD-KTGDLAALMFVHEDEDILLITDDGTIIRARAADVRLCGRATQGVRIMRLA
EGTVVGV-----
>tr|A0A0F9JN08|A0A0F9JN08_9ZZZZ Uncharacterized protein (Fragment) OS=marine sediment metagenome GN=LCGC14_1737400 PE=4 SV=1
-KDLIKKEPTIVIFTKNQYIKRVSVEEYRSQGRGGRGKKGMTIREEDFIIDLFVCSTHDTILVFTSKGRVYSLNCFEIPLQTRTARGKPIINVIPLQSGE
NISSMIPINNF-TNEMLIMTTKNGIVKKTPLKLFSKFKSTGVRAQKIRPDDKLVSVKRLSEIEDIFMATKLGYAIRFDESELRELGRTSMGVKGADLREG
DEVIDSLLVSDDEIILTLTKNGYGQRAYAREYRKTGRSAKGVINVSLNR-DKGDEVIAIRIAKDLDLLVGTEKGQVIRIPIKSIRITHRTAKGVRVIKLY
EDFVVAI-----
>tr|Q0DME7|Q0DME7_ORYSJ Os03g0812000 protein (Fragment) OS=Oryza sativa subsp. japonica GN=Os03g0812000 PE=4 SV=1
-LDIIPNEEMLLILSEKGYVKRMKPNTFNLQNRGTIGKSVGKMRMNDNTSDFIVCQTHDHVLYFSDKGIVYSARAYKIPECTRAATGTPLVQLLSLSDGE
RITSIVPVNEF-EDQYLVMLTVNGYIKKVPLNAFSAIRTSGIISIQLAPGDELKWVRRCGDDDLVALASQNGMVIVNTCNKLRALGRKTRGVLAMKLKEG
DKMASMDIIPAPPWLLFIADNGIGKRVPLNAFRQGNFNRVGLQGYKLPP-DC-SLAAVFVVGFDEQVVLVSQSGTVNRIKVKDISIRSRSARGVILMRLE
HAKIQSA-----
>tr|W5FFQ8|W5FFQ8_WHEAT Uncharacterized protein OS=Triticum aestivum PE=4 SV=1
-MDVIPNEEMLLILSEKGYLKRMNPNTFNLQNRGTIGKSVGKMRTNDNMSDFIVCQTHDHVLYFSDKGIVYSERAYKIPECTRVAAGTPLVQLLNLSDGE
RITSIVPVNKF-EDQYLVMLTVNGYIKKVPLNAFASIRSTGIISMRLVPGDELKWVRLCRDDDLVALASQSGMVIVNTCNRLRPHGRTTRGMGAMRLKED
DKMAAMDIIPSPPWLLFIAENGYGKRVPLNAFRQSSFNRVGLRGYKLPE-DC-RLAAVFVVGEEEQVVLVSHGGTVNRIKVKDISIQGRAAKGVILMRLE
HAKIQSA-----
>tr|Q2HTL3|Q2HTL3_MEDTR WD40-like OS=Medicago truncatula GN=MtrDRAFT_AC150269g2v2 PE=4 SV=1
-IDVIPNEEMLLTLSEKGYLKRMKPSTFNLQHRGTIGKSVGKLKMNDSMSDFIVCRAHDFVLYFSDKGTVYSARAYKIPECSRTASGTPLVQILSLSDGE
RITSIIPVSEF-DDQFLLMLTMQGYIKRVPLNSFSSIRSSGIIAIQLVPGDELKWVRCCTNDDFVAMASHNGMVILSLCIQIRTLGRNTRGALAMRLKEG
DRMASVDIIPAGPWLLFISESGHGKRVPLSRFRMSSLNRVGLIGYKFSA-ED-RLAAVFVVGFDEQVVLVSQSGTVNRIKVRDISIQSRFARGVILMRLD
HAKIQTA-----
>tr|M0T0K4|M0T0K4_MUSAM Uncharacterized protein OS=Musa acuminata subsp. malaccensis PE=4 SV=1
-IDVIPNEEMLLTLSEKGYVKRMKPNTFNLQHRGTIGKSVGKMRVNDSMSEFIVCHTHDHILYFSDQGIVYSARAYRIPECSRTAAGIPLVQLLSLSEGE
RITSIIPVSEF-EDQYLIMLTVNGYIKKVSLNAFSAIRAPGIIAIQLVPGDELKWVRRCADDDLVAIASQNGMVIVNYCNKLRALGRRTKGVISMKLKRR
DKMASMDIIPAPPWLLFVSESGHGKRVPLSAFRLSSFRRVGLIGCKLLP-DY-RLAAVFVVGFDEQVVLVSQSGTVNRIKVCDISIQSRSGRGVLLMRLD
YAKIQSA-----
>tr|A0A060A399|A0A060A399_9GAMM DNA gyrase subunit A, C-terminal OS=Acidithiobacillus caldus ATCC 51756 GN=Acaty_m0014 PE=4 SV=1
-EDLIPDDPVIVTLSHAGYIKALSANEFRTQSRGGRGKLAASVKDGDFLEYIFTTTKHGVLLFFTDQGRVFARRGYQIPEGSRTARGRAIPNLLPLDAQE
KVATVYATRAD-TQGSLLMVTRQGTAKRIAPDQFTRIRSTGTRAINLREGDSLLAVLATQGEGEILLFTEAGRAIRFAEAEVREMGKNAAGVRTIRLQSE
DRVTAAIALEHEQKVLVVTSDGMGKVTTAEEFRRTARGGQGVIAARKPI-AGA----ALINGEGEDILLLSSQGIVTRIPANSIRETSRTARGVRLMRLD
AGQILAV-----
>tr|H3KCE0|H3KCE0_9BURK Putative DNA gyrase, A subunit (Fragment) OS=Sutterella parvirubra YIT 11816 GN=HMPREF9440_00392 PE=4 SV=1
-RDLIPRRDMVVTISKGGFIKMQELADYAAQGRGGKGRNVQSMTKDDEVEHLFVANTHDILLCFSSMGRIFALDVFDLPEGKSSARGRPIVNLLSLDEGE
RITFTQPITEF-DSQIVILATANGYVKRTPLSAYRNARPTGLRAMTLVEGDSLVSVSVTDGSGDLFVVSSAGRALRFPQSSVRVMGRTAKGVRSMRLPAG
ARVLNCTPITDSAKILVATENGYGKRVELSEFTPHGRGTMGQMLIRCSA-RNGAVAAAELVGETEDVIMLCNRGRMIRTRIAEIGVYGRGAHGVRLFRLD
DELV-SM-----
>tr|G7EWY6|G7EWY6_9GAMM DNA gyrase subunit A OS=Pseudoalteromonas sp. BSi20311 GN=gyrA PE=4 SV=1
-EDLINEENVVVTLSHEGYVKYQALTDYEAQRRGGKGKSATKMKDEDFIERLLVANTHDTILCFSTAGRLYWLKVYQLPLASRAARGKPIVNLLPLEADE
RITAILPVR---DDKYIFMATAFGTVKKTPLTAYSRQRASGIIAVNLNEGDSLIGVDITDGSNEIMLFTDAGKVVRFKEAGVRPMGRTATGVRGIKMPDD
QRVVSLIVPKN-GAILTVTENGYGKRTQLEDYPSKSRATQGVVSIKVSE-RNGAVVGAVQVDDNDEIMIISNRGTLVRTRVNEVSTVGRNTQGVILIRTI
DEQVVGL-----
>tr|E3F304|E3F304_KETVY DNA gyrase subunit A OS=Ketogulonicigenium vulgare (strain Y25) GN=EIO_1547 PE=4 SV=1
-EDLIEREDMVVTVTSGGYIKRTALAEFRSQKRGGKGLSSMQTKDEDVVTALFVANTHTQLLFFTTDGMVYKLKCWRLPLAARTARGKAIVNILPIPQGV
TIAAIMPVDRP-DELQAVFATSDGDVRRNALSDFTNVMRNGKIAMKLPEGVSLVDVKIASEDDDVLLVTNSGRAIRFQTTDVRVKGRDSTGVRGIRLQGD
DRVVSMDIIKHENLILTITRSGAGKLSSSHDYPVRGRGGMGVRAMDAAM-RGGDLVAAFPVEMDDQVMLVTSTGQSIRVPVKGISFRSRGAGGVRVFNTG
TDHVVSV-----
>tr|R5E327|R5E327_9BURK DNA gyrase subunit A OS=Parasutterella excrementihominis CAG:233 GN=BN548_01755 PE=4 SV=1
-KDLIPLREMVVTLTDTGYIKSQASIEYRAQKRGGQGKRAAQMKEGDIINQLFVATTHDVLLCFTNKGRLHWLNVWDVPEGSSSSKGRPIVNMLELTDDE
KVTAVLPISD--KDLYIFMATADGTVKKTPIGDFKNQRRAGINAINLLEGDVLVGAAVTDGKHDVMLFSDNGKVVRFSEDEVRAMGRAATGVRGMRLDEG
QKVISMLVCGDDVTVLTATEFGYGKRSPLAEYTRHGRGTKGIISIQTTE-RNGKVVSALLVKENDEIILLTSTGKLVRTRVNEIRVLGRNTQGVTLISME
EGKLVGL-----
>tr|V4QE01|V4QE01_PSECO Uncharacterized protein (Fragment) OS=Pseudomonas chloritidismutans AW-1 GN=F753_07570 PE=4 SV=1
-ADLITEEERVVTISHGGYAKSQPLAAYQAQRRGGRGKAATGVKEEDYVEHLLVANSHTTLLLFSSKGKVYWLKTYEIPEASRTSRGRPLVNLLPLDEGE
RITAMLQVDLEDTGSYIFMATANGTVKKTPLVQFSRPRTSGLIALKLEEGDTLIAAAVTDGAQEVMMFSDGGKVIRFKESKVRIMGRNARGVRGMRLPEG
QRIISMLIPES-AQILTASLRGYGKRTAMEEFPRRGRGGQGVIAMVTNE-RNGPLIGAVQVLEGEEIMLISDQGTLVRTRVDEVSSLGRNTQGVTLIKLS
KGHLVGL-----
>tr|S4VSC0|S4VSC0_9FUSO DNA gyrase subunit A (Fragment) OS=Fusobacterium hwasookii ChDC F300 GN=gyrA PE=4 SV=1
-EDLIKDEEIIITYTNKGYVKRIEASKYKAQRRGGRGVSALNTIEDDYAEKIISASTLDTIMVFTDKGKVYNIRAYEIPDLSKQSRGRLLSNIINLSEGE
KVRDTLVIKEFASEKEVVFITKNGLIKKTSLGEFKNINNSGLIAIKTREDDDIIFVGLIENKEEILIATHDGYCTRFLTDTIRATGRSTQGVKAITLREG
DAVVSAMLIKNETDILTITENGYGKRTSLDEYPQYNRGGKGVINLKASE-KTGKVVSVLEVNEDEELMCITSNGIVIRTSISEISRIGRATQGVRIMKVA
DDKVAAI-----
>tr|K2BGN7|K2BGN7_9BACT DNA topoisomerase (ATP-hydrolyzing) OS=uncultured bacterium (gcode 4) GN=ACD_41C00045G0002 PE=4 SV=1
QEDLIPKEAAIIMITRDGYIKRLTPDTFKQQHRGGKGIIGLTAKEEDSVDQLFSTNTHADILFFTSRGRVFQLKAYEVPVASRTAKGQAVVNFLQLGPEE
KVTSALSCADMSGGKFLVMVTSNGTIKKTSLDAFENVRRSGLIAITLKGKDALEWVKPSTGTDNIILATDNGQSIRFQEQAVRAMGRTAAGVRGIKLKTN
DSVVGMDIISQNAELCIVMRNGYGKRTDLKSYKVQGRGGSGIKTAKITD-KTGKIVLGFVVTEDSDLLIISKQGQVIRLPLKSVPIISRDTQGVRLMRFK
IEDVASVTH---
>tr|A0A0G1ZJM7|A0A0G1ZJM7_9BACT DNA topoisomerase (ATP-hydrolyzing) (Fragment) OS=Parcubacteria bacterium GW2011_GWB1_52_7 GN=UY71_C0030G0001 PE=4 SV=1
EEDLIPEEETLVVVTRGGYIKRVKPESYRVQKRGGRGLIGMETKEEDVVEHLVSANTHSDLLFFTSTGKVFQVKAYEIPEASRISKGKAIFNFLSLGQNE
TIMSILAAPKEKGSDFLVMVTKDGVIKKVEGSVFRDVRRSGLIALTLKSGDALRWVKLTSGTNEIILVTKFGQAVRFSEKDVRPMGRQAAGVHAMRLKKN
DEVVGMDVITEGANLLVMMANGYGKKTPLKQYKRQRRGGSGIKTAKVTP-KTGHVVVTHVLTEESQIVAISQRGQVIRTELSAIPTLGRATQGVRIMRLD
ES-LASITT---
>tr|G5J6V6|G5J6V6_CROWT DNA topoisomerase (ATP-hydrolyzing) (Fragment) OS=Crocosphaera watsonii WH 0003 GN=CWATWH0003_3199a4 PE=4 SV=1
DTDLIANEQAIILLTEQGYIKRMPVSTFEAQQRATRGKAAAKIKEDDVVEHFLTCCDHDQVLFFSDRGVVYAVNAYQIQAASRTARGIPIVQML-IPKDE
KITSIVAVSEFSDDVFLVMLTRNGYIKKTALSAFSNIRTNGLIAISLGDGDQLRWVRLTREEDSIILGTSNGMSIHFQADNLRPLGRATRGVKAMKLKKG
DELISMDILT-TAGMADTEED-EEILDNENEKLTEEETTAGPWILAITN---------------------------------------------------
------------
>tr|W4V7R8|W4V7R8_9FIRM DNA gyrase subunit A OS=[Clostridium] straminisolvens JCM 21531 GN=JCM21531_2742 PE=4 SV=1
IEDLIEVEENVVTLTHFGYVKRLPTSTYKSQKRGGKGIMGLSTREEDFVEHLFITSTHDYLLFFTNKGKVYRLKTYEIPEAGRQAKGMAIVNLLQLDQNE
KVTTVIPIS---EGFYLFMATKHGIVKKTDLMEYDNIRKGGLTAVSLRENDELIDVRLTDGTKNILLVTRKGMSIRFNEKDVRPLGRAAQGVKGITLDED
DEVVGMSADI-NASVLVVTEKGFGKRTELDEYKVQIRGGKGILTYRVTE-KTGKLAGMKLVSEDDDVMMISSDGSIIRIKAKDISILGRATQGVTLMRMD
DGSVVSIAR---
>tr|A0A0G1VW62|A0A0G1VW62_9BACT Gyrase subunit A protein OS=Parcubacteria bacterium GW2011_GWA2_49_9 GN=UY50_C0031G0018 PE=4 SV=1
EEDLIPDTEAVLVLTKGGYIKRTDPEEYRKQRRGGVGVVDLDTKDEDFVTHVITGTTHNDFLFFTDKGKAYQIKMYEIPEGKRATKGKSIMNFLSLAGDE
KVTSILPMPKATTALSLLMVTKNGVGKKTAAAGFHDVRRSGLIAIKLHPGDELVSASFVEKGDEAVLVTKKGQSIRFKESDIREMGRGAGGVNAMRLGKG
DSIVGTGIVSKSPELLVIMQNGYGKKTKLKEYKTQKRGGSGIKTAKITS-KTGELIAAHVITSDSPVFNIPTYKRYERYK--------------------
------------
>tr|S5DRH6|S5DRH6_9ACTN Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit (Fragment) OS=Candidatus Actinomarina minuta PE=4 SV=1
IEDLIEDEEIIVSVSSNGYVKSVASTSYKKQGRGGKGVKAAS-SDEDVIEHLLSTSVHSYLLFFTDKGKVYRAKAHEIPKTNRTARGSLIQNVLSMGQDE
KVQAIIDTR--TE-KFLLIMTEKGTVKKSKFKDFDSNY-KSLQAIKLKDDDRVVSVKTTSGKEDVILVSQKGQAIRFDETNLKPQGRTAMGVRGIKLREG
DKVVGAATS--DETLLFITAKGYGKRTKLDEFRRAGRGGMGVKALKVTE-AKGNLVGARSVDEDTEVMLMSTGGTAIRCAVKQIKQMSRAAQGVRVMKLS
SEEVSAFIP---
>tr|X0SBC0|X0SBC0_9ZZZZ Uncharacterized protein (Fragment) OS=marine sediment metagenome GN=S01H1_01202 PE=4 SV=1
IEDFISSEDIVITYTRDGYLKRLPLSTYRKQRRGGKGKIGMTTKLEDLVDQVFVTTNLHDILFFTSKGVVYRRRAYQIPEGGRTSRGVAIVNLL-IGKDE
HITTIIPLESNS-GKYLFMATKKGKIKKVPLSHFYNLRNVAIIAIRLLPEDELIGVRLAGEEEKIILTTKRGNSTCFSGN-IRPLTRVACGSKGISIKEN
DHLLNISLVS-DEDLLIVTEGGLAKRTPLKKFREKKRGGKGVRSIKLTK-EKGLIVAVKVV-KEDEIVLISQQGIVIRVPVKEIR-TGRYSQGVKAMNLA
PEIVASVAL---
>tr|X1DVR7|X1DVR7_9ZZZZ Uncharacterized protein (Fragment) OS=marine sediment metagenome GN=S03H2_05153 PE=4 SV=1
IEDFISLEDIVITYTRDGYLKRLPLSTYRKQRRGGKGKIGMTTKLEDLVDHVFVTTNLHDILFFTSKGIVYRRRAYQIPEGGRTSRGVAAINLL-IEKDE
HITTLIPIESNSNEKCLFMATKKGKIKKVSLSRFSNLRNIGIIALRLLPDDELIGVKLAEDKEHVILTTKHGKSIRFSGD-IRSLGRISFGVKGMILKAE
DYLINISLVP-DKYLLLVTEKGYAKRTVLKKFRESNRGGQGLKSIKITK-ERGPVVDVKVV-SEDQLVLISQNGILGLGTLPGKLARDIFSRG-------
------------
>tr|A0A0F9RW51|A0A0F9RW51_9ZZZZ Uncharacterized protein (Fragment) OS=marine sediment metagenome GN=LCGC14_0925640 PE=4 SV=1
MEDLIAEEDMIVTITHSGYIKRVPATTYRQQKRGGIGVSGTNLKEGDFVEHLFIASTHNNVLFFSNKGRVYRLKVYELPSASRQARGQNIINILPFKKEE
KVAAVLSIP---HAKYIIMGTKEGLVKKSKLTAYETSRKEGIIAINLRTTDELIDVKLSNGESDVVIVTKKGKAIRFKEEDSRPMGRVSMGVKGIALGDK
DIVLGMDII--EAKLLVITEKGYGKRTELAKYPVQRRGGRGVKTIQLVK-SKGDLAAVRKVKDDTELIVISEEGVVIRVKAKDISIQGRATQGVRIMSLR
DKRVSALAR---
>tr|W1U185|W1U185_9FIRM DNA topoisomerase (ATP-hydrolyzing) (Fragment) OS=Negativicoccus succinicivorans DORA_17_25 GN=Q612_NSC00218G0001 PE=4 SV=1
DLDLIPDEPMIITLTQQGYIKRMHANTYRTQRKGGAGITGIKTKDDDFVTKVLTTSTHNTLLFFTTAGRVYRLVANDIPKATRTARGTHLVNCIPLEKDE
QVTEIYDISSFANYEYLLMVTRQGFVKKTLLSEYTNVRQSGLIAINLREGDELIKVVTTTGDDHIIIGTKTGMAIVFSEA-VNPTGRASLGVIGVRFKQG
DEVVGADVLT---EVLTLSSDAYAKRNKATAYSVQQRGGQGARNFK----KGSTVVGLLTV-KNEEMLVITESGIVIRVPVDSISLKGKNTIGVKVQRLD
ETRIASVAL---
>tr|A0A0E9CU73|A0A0E9CU73_CHLTH DNA gyrase subunit A OS=Chlamydia trachomatis GN=gyrA PE=4 SV=1
IEDIISDESVIITISGDDYVKRMPVKVFREQKRGGQGVTGFDMKGSDFLKAVYSASTKDYLLIFTNFGQCYWLKVWRLPEGERRAKGKPIINFLEIRPGE
QVAAVLNVKRFEQGEYLFLATKKGVVKKVSLDAFGSPRKKGIRALEIDDGDELIAARHANDEEKVMLFTRLGMAVRFPHDKVRPMGRAARGVRGVSLKNE
QDFVVSCQVVTDQSVLVVCDNGFGKRSLVCDFRETNRGSVGVRSIVINQ-RNGDVLGAISVTDCDSILLMSAQGQAIRINMQDVRVMGRATQGVRLVNLR
EGTLVAMEK---
>tr|R6DVI5|R6DVI5_9FIRM DNA topoisomerase (ATP-hydrolyzing) OS=Firmicutes bacterium CAG:176 GN=BN516_00536 PE=4 SV=1
IEDLIEEEQCVFTLTENGYIKRTPVSEYAAQSKGGMGKKGITTREEDTVVDVFTASTHDYILFFTDTGKVYRKKGYQIPESGKAAKGVNIVNIL-VETGE
RVQAMLHFRETDEELYLFMTTRNGTVKRLEVSALKNLRNNGIRALTLDEGDELISVTETRGHDRMLIATHDGQAVCFDET-VRAMGRTAVGVRGIRLREG
DYVIGAARAD---TVLSITENGYGKRTPIEEYRITNRGGMGIRNYMVTD-KTGPVVGMKVV-DTEDLLLVTAAGILIRTPVENIRVAGRATQGVIVMRFK
EEDVISLAL---
>tr|B7AU88|B7AU88_9FIRM DNA topoisomerase (ATP-hydrolyzing) OS=[Bacteroides] pectinophilus ATCC 43243 GN=BACPEC_02277 PE=4 SV=1
MEDIIPDEPVVIARTNLGYIKRMTLDNFKAQHRGGKGIRGMQTIDQDYIEDLFMTTSHHYLMFFTNTGRAYRMKAYEIPEAGRTARGTAVINLLQLQPGE
TITAVIPIR---DNNYLFMATRNGIVKKTKVTEYSNIRKNGIQAITIRDNDELIEVKLTDDTKDIMLVTKLGMCIRFKETDVRPTGRTSMGVIGMDLMDE
DQVVGMQIDS-GDSLLIVSEKGLGKRTLIEEFTTQHRGGKGVKCYKINE-KTGNVVGVKAVDDTREIMLITTEGIIIRIKAQDISILGRITSGVKLINLE
DGTVASVSK---
>tr|R6K1H5|R6K1H5_9FIRM DNA gyrase subunit A OS=Eubacterium sp. CAG:252 GN=BN564_01012 PE=4 SV=1
MEDLIPDEACVIARTNMGYVKRMTPDNFKSQHRGGKGIKGMQTLEEDYIEDLFMTTSHHVLTFFTNTGRAYKLKAYEIPEAGRTSRGTAIINLLQLAAGE
TITAVVPVKIE-DNDYLFMATKNGIVKKTPCKEFANIRKNGIQAMTLRDDDELIEVKLTDDTTEVMMVTKLGMCIRFKATDVRPTGRSAMGVIGMNLMDT
DEVVGVQLNT-GDTMLIVSENGMGKKTDISEYAVQHRGGKGVKCYKITE-KTGNVIGAKAVDDTREIMLITTEGIIIRLACRDISTLGRITSGVKLINLD
DNKVATVSK---
>tr|V6DUF2|V6DUF2_9EURY DNA gyrase subunit A OS=Halorubrum sp. AJ67 GN=gyrA PE=4 SV=1
HEDLIPEEECVVVMSEDDYIKRMPLDEFRAQNRGGKGIIGTGLKEGDRVSSVFAANSHDYLLVFTNRGQIYELKTYEIPEMSRTARGKSAVNLL-LDDGE
EIESVVNTEDLDDDEFLTMVTRDGYIKRTAVDEFGNIRSTGIRAIRLEDGDELVDVEVTDGDRDIVIGSKHGMAIRFDES-ARAMGRTARGVIGIDLREG
DAVAGVAAID-HNWVLTVTENGYGKRSDLDEYRPQSRNGKGLVDIKTGD-RNGEVVAIEAV-TGDHLVAMSAAGQIMRTRVEEISTVSRNTKGVIVMNLD
PDEVASVDI---
>tr|A0A0P8A5D9|A0A0P8A5D9_9EURY DNA topoisomerase subunit A OS=Candidatus Methanoperedens sp. BLZ1 GN=gyrA PE=4 SV=1
TEDLIPKEDDVITITNSGYIKRIAVDSYKQQRRGGKGVMGMETKEEDFVSDLFIGNTHDYLLFFTDKGKVYWLKVYGIPEAGRQARGTAIVNLL-LEQGE
KITAYIPISKF--KHYLLMVTKKGTAKKTQLTDFANVRKTGIIAISLDEGDKLVSVKLTDGTKEMVIGTKHGKAIRFNEN-VRDMGRSAYGVRGVRLVGE
DEVVSMAVVE---TLLTVTENGFGKRTVFDEYRTSNRGGQGVITIDVNI-RNGNVVDIRTV-RDDEIMVTTSNGIIIRVPASGIRVQGRNTQGVKIMNVG
EKRVVGVAT---
>tr|H1LHF3|H1LHF3_9LACO DNA topoisomerase (ATP-hydrolyzing) OS=Lactobacillus kisonensis F0435 GN=HMPREF9104_02044 PE=4 SV=1
DEDLIEEEDVIVSLTHNGYIKRLPTTEFKAQNRGGRGVQGMGVHNDDFVEHLVSTSTHDVLLFFTDAGKVYRMKGYEIPEYGRSAKGIPIINLL-INNDE
KIEAVINISDKDIEKDLFFVTLHGTVKRTPVEEFANIRSNGLKAIHLKDDDQVINVLIVDKDQNIIIGTHKGYAVSFKAA-VRSMGRSATGVRGIRLRDS
DYVVGADTLK---EVFIISENGYGKRTAAVEYPIKGRGGKGIKTANITE-KNGPLAGLTTV-TAEDIMLITNKGVMIRFDVDDVSQTGRATLGVHLIRMD
DDKVATMAK---
>tr|T2JNX4|T2JNX4_CROWT DNA gyrase subunit A OS=Crocosphaera watsonii WH 0402 GN=CWATWH0402_1108 PE=4 SV=1
TTTSTSNKDKVESKSNQQT--ETVTQPFNLFTPPCWRSPDDKIPDNHLPIYSEPIQEREQFVVITDIGKAYPVNVADVPPIDIQPISLLSLLPKSQRDSK
KVISVFFVLE--ENHDLLLLTNQGKIKRIQLSELDGLTNRGLVLIKLKDNDYLEFISPTKEGEEVAIAMSSGRVLRFPVVDIHIMGRNAQGNQALKLRYG
ENIISCVTLDENKTVLLVSKLGYAKRLNITGLRMTKLGDIGTQALQFAQKT-DSLLGMIKAS-DRNVTLLTNQNNTVNIVAKKVRIWGKDGQGDRLIKLS
NQVIDYLI----
>tr|A0A0D0II15|A0A0D0II15_9MICO DNA gyrase subunit A (Fragment) OS=Leucobacter komagatae GN=SD72_16170 PE=4 SV=1
MEDLIPEEEMVITVTRGGYVKRTRIDNYRSQHRGGKGVRGAQLRADDIVEHFFVTTTHHWLLFFTNTGRVYRAKAYEVAEGGRDAKGQHLANLLALAPDE
QVTQILDLR---DASYLLLATRDGLVKKTPLTEYDTNRTGGIIAIKLRDGDELVQALIAGAEDDVLLISRQGMSIRFTASDLRPMGRSTSGVRGMNFRDG
DALLAASRLS-EGYVFVVTEGGYAKRTAVSEYRVQQRGGYGIKVAKLDE-GRGDLAGGFIVDESDEVLVVLASGKVVRSGVAEVPAKGRNTMGVVFARFP
EGRIIGIAR---
>tr|A0A0E9FX78|A0A0E9FX78_CHLTH DNA gyrase subunit A OS=Chlamydia trachomatis GN=gyrA_2 PE=4 SV=1
EEDLIPEEDVVVTITRSGFVKRTKVSEYRAQHRGGKGIKGTTLRGDDVVEHFGIGSTHDWHLFFTNQGRVYRVKGYELPEGSRESKGQHIANLLAFQPDE
KIASAISLR---QAQYLVLATKFGYVKKTRLADYDSARAAGLIAINLKELDQVVSARLVNEGDDLLLVSSKGMSVRFTANDLRPMGRATSGVTGMKFRRG
DSLLTMDV-I-ESEVFVVTEGGFAKRTSVDQYRVQGRGGLGIKVANLVE-ARGDLVGALITQPDDEILVIMSGGKVVRSRVDEVNLTGRNTQGVTFARPD
GDKVIAIAL---
>tr|A0A0K2RK64|A0A0K2RK64_9MICC DNA gyrase subunit A OS=Arthrobacter sp. Hiyo8 GN=AHiyo8_34870 PE=4 SV=1
MEDLIPEEEVVVTITRGGYVKRTRSDNYRSQQRGGKGVKGAQLRGDDVVEHFFVTTTHHWLLFFTNLGRVYRAKAYELAEAGRDAKGQHVANLLAFQPDE
HIAQVLDLR---QAPYLVLATKNGLVKKTRLEDYDTNRTAGVIAINLRDEDELVSAQLVSETDDLLLVSRKGQSIRFTATDLRPMGRATSGVTGMKFRED
DELLAADV-V-GSFVFVVTEGGYAKRTAVEEYRLQGRGGLGIKVAKLQE-ERGDLVGALIVNEEDEVLVVMEGGKIVRSAVAGVPAKGRDTMGVIFAKPD
KNRIIEVAR---
>tr|A0A0R2X8S1|A0A0R2X8S1_9BACT DNA gyrase subunit A (Fragment) OS=Verrucomicrobia subdivision 6 bacterium BACL9 MAG-120507-bin38 GN=ABS31_03575 PE=4 SV=1
VEDLIPNQDVVVTITRGGYAKRTKADLYRSQRRGGKGVKGAALKQDDIVEHFFTASTHDWLLFLTNQGRVYRAKVHELPDAGRDARGQHVANLLAFKPNE
TIASVIGIN---SLPYLVIATKGGIVKKSPLSEYDSPRTGGLIAISLKDGDEVVAASAITAKDELLLISKKGMSLRFTADDLRSMGRSATGVIGMKFRSG
DELLTMATIRSKSFVLTATDGGFGKRTDISEYRLQSRGGIGVKAAKVDEGARGGLVGALIVNESNEILVITSGGVVMRTPVKEVRQTGRDTLGVRLVNLD
QGFVVSLAK---
>tr|K1S3Y0|K1S3Y0_9ZZZZ DNA gyrase subunit A (Fragment) OS=human gut metagenome GN=LEA_18072 PE=4 SV=1
IEDLIPNENCVFTLTTLGYIKRQSVDTYQTQHRGGRGVKGMTRREEDVAETMFTCSTHDYIMFFTSEGKVYRLKGYEIPEGSRNSKGMNIVNILPLGADE
KVTAMIRVP--TEKLYLCMLTKNGVIKRTELDAYKNVRKNGIFAINLDEGDELRFVKLTDGEKQILIATRKGMCISFNENDARCIGRTARGVKAITLSEG
DEIAGMCVPE-NKKVLTVSETGFGRRSEFDNYRVQSRGGKGLINYH-TE-TYGDVAAVAMVGEDEDVIMISSDGIIIRIPAKDISVFARPSKGVRVMKTN
EGKVATLSI---
>tr|K1SEM7|K1SEM7_9ZZZZ DNA gyrase, A subunit (Fragment) OS=human gut metagenome GN=LEA_16160 PE=4 SV=1
PEDFYADDDMVITISHMGYIKRTPLAEYRTQNRGGVGAKGSATRDEDFIEHIYVASMHNTMLFFTEKGRCYWLKVYEIPEGARSSKGRAIQNVI-IEPED
KVRAYINVKRLVNNNYIIMCTKDGTIKKTKLEAYSRPRQNGVNAIVIREGDQLIEAKLTSGNAEVLIAAREGKAIRFNEN-VRPIGRVGAGVRGISIDED
DEVVGMICIE-KQDVLVLSENGYGKRTDLDEYRITNRGGKGVKTINITE-KTGKLISIQAV-TENDLMIINRSGLTIRTAVSQIRLAGRATQGVRIINLR
EG-IASVMA---
>tr|R6WNS7|R6WNS7_9PORP DNA gyrase subunit A OS=Parabacteroides merdae CAG:48 GN=BN675_01533 PE=4 SV=1
PEDFYADDEMIITISHMGYIKRTPLSEFRAQGRGGVGAKGSETRDEDFVEYIYPASMHATLLIFTAKGKCYWLKVFEIPEGAKNSKGRAIQNLL-IEPDD
KVNAFIRVKKLINSHYLLFCTKKGVIKKTLLEAYSRPRQNGVNAITLREDDGLIEVCMTNGNNEVLIANRNGRAIRFHEN-VRVMGRTASGVRGMTLDDD
DEVVGMVCIK-KETVLVVSEQGYGKRSNIEDYRITNRGGKGVKTINITE-KTGKLVAIKNV-TENDIMIINKSGITIRMKVSDLNVIGRATQGVRLINLG
KRDIASVCK---
>tr|K2CBM3|K2CBM3_9BACT Uncharacterized protein (Fragment) OS=uncultured bacterium (gcode 4) GN=ACD_39C00715G0001 PE=4 SV=1
LESLMQEEDIIITMTKNGYVKRMSPDVFRQIGRGSKGSNVMGVKEDDVVEQMFLATTHSFLMVFTSIGKVHWIKGHQIPEGGRTASGRAMVNLL-LEENE
NLTAILPVKTFDATRRLFMVTRRGVCKMVMLSAFARPKARGIIALKLDEGDELISVKTIFGGEQVVIATKNGYAIRFGEN-VRVMGRVTRGVKAITFREK
DEVIGMEVFSQEGKLLTVSALGFGKQTDVNSYRVTHRGGKGVINLKIMD-KTGEVLAIKRM-FSDELMLVTTNGKVVRLNVDSIRNTGRAASGVKLITLD
DDRLISVVR---
>tr|A3SWF4|A3SWF4_9RHOB DNA gyrase subunit A OS=Sulfitobacter sp. NAS-14.1 GN=NAS141_05938 PE=4 SV=1
DEDLIAREDMVVTVTSGGYIKRTPLVDFRSQRRGGKGVSGMQTKEEDVVTTLFVANTHTQLLFFTTDGMVYKLKTWRLPQGGRTSKGKAIVNIL-IPTGV
SIAAIMPVDR---------ATSAGTVRRNKLSDFTNVMRNGKIAMKFEDDTTLINARIASNDDDVMLVTNSGRAIRFPAT-VRVFNSASVGVRGIKLNGD
DKVVSMSIIRHENLLLTITEKGAGKLSSSHDYPVRGRGGLGVTAMDKAMRG-GDIVASFPVE-DDQIMLATSKGQSIRVPVEGISFRSRSAGGVKVFDTG
RGVVVSVAW---
>tr|K2FJS4|K2FJS4_9BACT DNA gyrase, A subunit (Fragment) OS=uncultured bacterium (gcode 4) GN=ACD_6C00635G0003 PE=4 SV=1
REDLIPEEQMVLTVSKSGYAKTQPLSDYAAQRRGGRGKSATSMKEDDYIQHLIVTSSHATVLCFTNVGKVYRLKVYEVPQASRGAKGRPMVNLL-LDENE
TITAILPVIDFRKNFYVFMATEYGTIKRVELEQFSNVRSNGLRAIEL---DTLIGVAITDGEQQIMLFSNEGKAIRFAET-VRSMGRSAKGVRGMRVTIG
AAA-------QTGEVLCASENGYGKRTPVDDFPTKKRGGKGVIAIKTSERN-GQLVGAVAID-SKELMLISDGGTLVRTRASEVAQTGRNAQGVRLIRLG
NELLVGVVS---
>tr|A0A099U8I5|A0A099U8I5_9HELI DNA topoisomerase (ATP-hydrolyzing) (Fragment) OS=Helicobacter magdeburgensis GN=LS74_03875 PE=4 SV=1
VEDLIPNEKVVVTMSHRGYVKRVLLKTYEKQNRGGKGKISGNTHEDDFIESFFVANTHDTIMFVTNKGQLYWLKVYKIPEAGRTAIGKAVVNLI-LSPDE
KIMATITTTDFNNDKSLVFFTKNGIVKRTNLKEYSNIRSVGVRAINLDGNDELVTAHIVGSSKELFIATQQGMCIRFGVD-LREIGRVSRGVTGIKFKAS
DCVIAATTIT--DKLLTVSEQGIGKQTLAGEYRLQSRAGKGVIVMKLTP-KTGKLVSVVNINDNMDLMVLTSSGKMIRVDTEAIRE-GRNTSGVKIVNVG
ND-VAYANV---
>tr|W7BVF3|W7BVF3_LISGR DNA topoisomerase (ATP-hydrolyzing) OS=Listeria grayi FSL F6-1183 GN=LMUR_06002 PE=4 SV=1
DEDLIPEEEVAITLTKRGYIKRLPLSTYRSQRRGGRGIQGMSTHEDDFVEHLVAASSHDTLLFFTNTGKVYRAKGYEIPEYGRTAKGIPLINLL-IESQE
QVNAVINVSEF--NSHLFFTTKHGVVKRTDISQFAKIRQSGLRAVDLRENDELISVQITDGNKNIIIATKQGQSIYFPEN-IRVMGRTAAGVRGIRLRED
DEVIGMEILE---KVLIVTEKGYGKQTPAAQYPLRNRGGMGVKTVTITE-KNGNLVAMKTV-SEEDIMLMTVSGVMIRFEIGTVSQTGRSAMGVKLIRLD
ENKVATVAK---
>tr|R5SUH8|R5SUH8_9CLOT DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium sp. CAG:762 GN=BN775_00353 PE=4 SV=1
DESLIPEENIVVTLTGKGYIKRLPVDTYKTQNRGGVGIRGMGTNDEDYVENMIESSSHDYILFFTNKGKVYRIKGYEIPEYGRQSKGLPIINLL-LEKNE
KVAALIRVANDEVSNNLVFATKSGLIKRTAISEFNNIRNNGKKFITLRDDDELISVEKTTGDNDILMASSNGRMVRFNEN-IRVMGRGAAGVRGINLE-G
GYLVGMSKAV---QVLVVTENGYGKKTDISEYRITNRGGKGVKTLNITD-KNGSIVAFKTV-NNSDLMIITNDGIVIRLDIDKISTMSRVTQGVKLINIR
ENCVSSIAV---
>tr|A0A0G0G848|A0A0G0G848_9BACT DNA topoisomerase (ATP-hydrolyzing) (Fragment) OS=Parcubacteria (Nomurabacteria) bacterium GW2011_GWC2_35_8 GN=UR91_C0033G0008 
DEDLMPEKETMLVLTAGGYVKCTDPSEYRAQKRGGVGVIDLETKEEDFVTKLVSGSTHSNLLFFTNLGKVYQMKMYDIPEGRRATKGKSIMNFLSLSGEE
KVNSILAMPKDKTPTSLMLVTKNGTAKKMSSESFKDVRRSGIIAIRLDKDDQLISALVTEKGNEVMIATAEGQSIRFKESDIREMGRTAGGVRGIKLGKS
DEVIGVDVIKKKGAFLTMSANGFGKKTELKEYKVQKRGGSGIKTAKVTP-KTGKLIVAKVLSGEEELIAMSKKGQVIRTTLKDISSLGRQTQGVTIMRLR
AGGIASLAC---
>tr|A0A0G0D1N6|A0A0G0D1N6_9BACT DNA topoisomerase (ATP-hydrolyzing) OS=Parcubacteria (Nomurabacteria) bacterium GW2011_GWA2_35_80 GN=UR92_C0012G0027 PE=4 SV=1
DEDLIPDKETVLVFTAGGYVKRTDPSEYHAQKRGGVGVVDLETKEEDFVTMLVSGSTHNDLLFFTNLGKTYQMKMFDIPEGKRATKGKSIMNFLSLNNDE
KVTSILPMPQEKSPISLMLTTKNGTSKKMSGESFKDVRRSGIIAIRLDKGDQLVSALLVEKGDEVIVATSGGQSIRFKESDTREMGRTAGGVRGIKLGKS
DEVIGVDVVKKTGAFLTMSVNGFGKKTSLKEYKVQKRGGSGVKTAKITP-KTGKLIVAKVLTGEEELIAMSKKGQVIRTALKDISSLGRQTQGVTIMRLR
AGNIASLVC---
>tr|A0A0R0I7C4|A0A0R0I7C4_SOYBN Uncharacterized protein (Fragment) OS=Glycine max GN=GLYMA_09G1202002 PE=4 SV=1
DIDVIPNEEMILALSEKGYMKRMKPSTFNLQNRGTIGKSVGKLKVNDSMSDFLVCHAHDHVLYFSDKGTVYSARAYKIPECSRTAAGTPLVQIL-LSDGE
RITSIIPVSE--EDQFLLMLTMQGYIKRVSLNLFSSIRSIGIIAIQLVPGDELKWVRLCSNDDFVAMASHNGMVMLSQCS-IRTLSRNTRGAPAMRLKKG
DKMASVDIIPAGPWLLFVSENGYGKRVPLSSFRISSLNRVGLIGYKFSAE--DRLAAVFVVG-DEQVVLVSQSGTVNRIKVRDISIQSRFA---------
RGILMRLDH---
>tr|M5X2T3|M5X2T3_PRUPE Uncharacterized protein OS=Prunus persica GN=PRUPE_ppa004605mg PE=4 SV=1
DIDVIPNEEMLLAFSEKGYVKRMKPNTFNLQNRGTIGKSVGKLRVNDAMSDFIVCRAHDHVLYFSDKGTVYSARAYKIPECTRTAAGTPLVQIL-LSDGE
RITSVIPVSE--ADQFLLMLTVNGYIKKVSLSYFSSIRSTGIIAIQLVPGDELKWVRCCTNDDLVAMASQNGMVILSSSD-IRALGRNTRGAVAMRLKEG
DKMASVDIIPAGPWLLFVSESGYGKRVPLSRFHSSKLNRVGLIGYKFALE--DRLAAVFVVG-DEQVVLVSQSGTVNRIKVRDISIQSRYA---------
RGILMRLDH---
>tr|R5QRZ4|R5QRZ4_9FIRM DNA topoisomerase (ATP-hydrolyzing) OS=Coprobacillus sp. CAG:235 GN=BN550_01395 PE=4 SV=1
DEDLIPVEDVIISLTNNGYVKRMPVDTYKSQNRGGRGVKGMSTTQDDVISSLIHMSTHDDLLIFTNKGKVYRLKGYNIPEFGRTAKGLPIVNIL-LDKDE
SVKSLININKKDNQWYLFFATEQGLVKRVDISEFENIRQTGKIAIKLKEDDALVGVKLTKGDDEILIAASNGKLVRFSEG-VRPMGRSASGVKGINVD-G
SKVIGMTTNR---LIMVVTEKGYGKMSPIDEYRVSNRGGKGVKTINVTE-RNGQIVAIRAV-ENEDLLIITDDGIVIRLPMEQVKTAGRATQGVRLIKVH
DSKVSSVEV---
>tr|T5CCQ7|T5CCQ7_HELPX DNA topoisomerase (ATP-hydrolyzing) (Fragment) OS=Helicobacter pylori FD506 GN=N404_06845 PE=4 SV=1
IEDLIANEPMVVSMSYKGYVKRVDLKAYERQNRGGKGKLSGNTYEDDFIENFFVANTHDILLFITNKGQLYHLKVYKIPEASRIAMGKAIVNLI-LAPDE
KIMATLSTKDFSDERSLAFFTKNGVVKRTNLSEFGSNRSSGIRAIVLDEGDELVSAKIVDKNKHLLIASYLGIFIKFPLE-VREIGRTTRGVIGIRLNEN
DFVVGAVVIS--NKLLSVSENGLGKQTLAEAYREQSRGGKGIIGMKLTQ-KTGNLVSVISVDDNLDLMILTASAKMIRVSIKDIKEIRRNTSGVKLIDT-
AD-VVYANS---
>tr|R7GJW7|R7GJW7_9CLOT DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium sp. CAG:307 GN=BN598_01047 PE=4 SV=1
NEDLIPRDDVLITITRGGYAKRMKTSEYRSQSRGGVGITGIKTKENDIVEHVISTSTHDFLLFFTNLGRVYKLKGYQIPEGNRTSKGIPLVNMI-FQDGE
HLAAVTNISDINQEQCIFFATKKGIIKRTSVSQFQNIRTNGINAINLTEGDELLQVEVTDGHREIILGASNGKAIRFNEE-VREIGRSATGVRGMKLNEG
DELVGMAVVR--KDILVVTEKGYGKRTDADEYRLQTRGGMGVKTLNITD-KNGRLASLRAV-NDLDLIATTNKGVTIRMHCADISQTGRAAQGVKLIRLR
DDHVSSIAI---
>tr|Q8GDZ7|Q8GDZ7_HELMO DNA topoisomerase (ATP-hydrolyzing) (Fragment) OS=Heliobacillus mobilis PE=4 SV=1
IEDLIAEEDAVVTITHNGYIKRLHVNTYKAQRRGGKGVTAMGTKEDDFVELLFITTTHHYLLFFTDKGKVYRLKTHEIPEASRTAKGTAIVNLL-ITGDD
KVNAVIPVKEFSKDQYLLTATRNGIVKKTVLQQYDSSRKEGLIALTLDDGDELIGVKLTDGESDILLATRNGMAVRFPEG-VREMGRTTRGVKGIELSKD
DFVVAMETFK-KIDLLMITESGMGKRTAVEEYRSQHRGGKGIISMRLTQ-KTGLMAGIKVV-RGDELMVISAEGVIIRLNVDEISRFSRVTQGVSIMKIN
PNKVVAVAR---
>tr|Q3HZJ3|Q3HZJ3_STREE DNA topoisomerase (ATP-hydrolyzing) (Fragment) OS=Streptococcus pneumoniae GN=gyrA PE=4 SV=1
DEDLIEESDVLITLSNRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRLKGYEIPEYGRTAKGLPVVNLL-LDEDE
SIQTVINVESDD-DAYLFFTTRHGIVKRTSVKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQS-VRGMSRIATGVKGVNLREG
DTVVGASLIT---EVLIITEKGYGKRTVATEYPTKGRGGKGMQTAKITE-KNGLLAGLMTV-QDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLD
QDQIVTFTT---
>tr|A0A0G0PX28|A0A0G0PX28_9BACT DNA topoisomerase (ATP-hydrolyzing) OS=Microgenomates bacterium GW2011_GWC1_39_12 GN=gyrA PE=4 SV=1
EEQLIPNEDTIITMSTSGYIKRVPPTSFKTQERGGKGVIGMTTKDEDAIDMVVSAKTHDNLLFFTEKGKVYQVRAWDLPEASRQAKGQAVVNVINIESGE
KVTSMLTYTLDQGVKFIIMATKKGVIKKSKLTEYENIRRNGLVAIKLDPGDELEWVKLTGGSDEILMVSHEGKSIRFNGEEVRGTGRDTMGVRGILLKGN
DYLVSMDVITKSHDFLTIMEKGIGKKTAIVGFPKQRRGGQGVKVADVKD-KTGKVIVSQIIPSTEGLIITSTKGQVVKLPIASIPRLGRATSGVILMRFT
DKDVAAATC---
>tr|K2CJ17|K2CJ17_9BACT DNA topoisomerase (ATP-hydrolyzing) (Fragment) OS=uncultured bacterium (gcode 4) GN=ACD_37C00580G0009 PE=4 SV=1
EEDLIPNEPTVITLTTTGYIKRQSLTSFRTQQRGGKGVKGMTTKDEDGIMNIRSCETHDNILFFTNKGKVYQTKAYEIDESSRTSKGTAVINLINIESGE
KVESFITYNKNDQFKYIFLATRNGTVKKTAMTEFENIRKSGIVAIKVDKNDELVWSNPTTGDDDIFVYTRNGKCIRFPEKLVRPLGRATRGVRGIKLTGD
DLVVGMDVVKKIPMLITIMENGYGKKTVVKEFNAQSRGGMGVKIAEVTV-KTGKVASSQVIPPCKEVIITSHKGQVVRIDINSIPKLSRATQGVILMRFS
KEDVSSITC---
>tr|X1S3D8|X1S3D8_9ZZZZ Uncharacterized protein (Fragment) OS=marine sediment metagenome GN=S12H4_13164 PE=4 SV=1
EEDLIPHQRVVVTLSSRGFIKRIPSRTYKPQHRGGKGIIGMVTREADAVRFLTVADTHDSLLFFTNRGKVFCLKCYELSADTRTAKGMAVVNLFPITADE
RVTAMVAVTDFTQGTFLLMATCRGKIKKTAVNNFASVRSSGLIAIDLGAGDELVATCMATDQDDVILAASRGQSIRFAVSSLRATSRTSGGVRGIRLSPG
DRVVDMDCVHP--FVLVVTTGGFGKLTPVSRYPRQHRAGSGVRTFKITQ-KTGEVADAKVVSS-QQLMIISADGIVIRTPVRGITIQGRSTEGVRLMRLS
QGKV-AIAC---
>tr|A0A0G1U8G0|A0A0G1U8G0_9BACT DNA topoisomerase (ATP-hydrolyzing) OS=Parcubacteria (Wolfebacteria) bacterium GW2011_GWA2_47_9b GN=UY19_C0003G0019 PE=4 SV=1
EIDLIPEEDTVITLSQSGYIKRVPSDTYKAQKRGGKGLIGSDVNDEDALVTFISGNTHDNILFFTDKGRVFQTKVYDIPQGSRTAKGKLMQNFLDLPPDE
NINAVIAYPDSAEKQYLVMLTADGTIKKTSVSEFANIRRTGIIAINLAKGDSLIGVKISGGKDEIIITTNGGQAIRFAETDTKPLGRAAAGVRGIKLKKG
DRVAGFDIIRTKQTLLVVSENGYAKQTPISEYKTQTRGGMGIKTSDVTP-KIGNIITGQILREEEELLAVSTKGQIIRIPLKDVRTSGRATIGVKIMTLK
EKKLAGVVA---
>tr|T1BFK8|T1BFK8_9ZZZZ DNA gyrase subunit A (Fragment) OS=mine drainage metagenome GN=B1B_05962 PE=4 SV=1
MEELIPKEDCFVILTEKGIVKRVPLEDYRSQKRGGKGIITST-WKEDVVRTAVSGNSHDNILYFTDRGRVFAGKVYEIEKRARTSIGVSVQAFL-LQQNE
LVKQIM-IPSFTEGSYLFIATKLGYIKKISASALENVRSNGLIIIGLEPNDAVVSIEVLRKGDRIAVVSEDAKIATFMPD-LRALGRTARGVRSMRLPRG
RTVLTAFAVL-SEYVLSVSEKGIGKRTISTEFPIHRRGSSGVFIFRESK-KTGKLVSALSV-RDDEILILTKEEKSIRTPINAIREISRVTSGVKLVNLE
KDLVVSVTR---
>tr|A0A0G1SB92|A0A0G1SB92_9BACT DNA topoisomerase (ATP-hydrolyzing) OS=Microgenomates (Amesbacteria) bacterium GW2011_GWA1_47_20 GN=UX92_C0036G0003 PE=4 SV=1
EEDLIPSEDTVVTITATGYIKRQSPSAFRAQHRGGKGVTGMTTKDEDEIAQILTANTHDSIYFFTNKGRVFRIKTYDLPEGSRQAKGQAVVNLINIEQDE
KLETVLPLGKNDGAKFLLMVTNHGTIKKTKISEFESIRQSGKIAIKLDKGDSLKWVTPTTGSDHVLLVSYEGKSIRFKEEDVRFTARDTMGVRGIELKSG
DYVVGMEVFPSFSDVLIVMEHGLGKRTGVKEWPLQKRGGQGVKAAEITP-KTGKIVSCISIDEVEQIILTAKSAQVIKLPLRNIPRLGRATQGVILMRFA
KKDVASVTC---
>tr|A0A0G1B6B0|A0A0G1B6B0_9BACT DNA topoisomerase (ATP-hydrolyzing) (Fragment) OS=Microgenomates (Amesbacteria) bacterium GW2011_GWA2_42_12 GN=UU93_C0002G0001 
EEDLIPAEDTVVTITSTGYIKRQNPSVFRAQHRGGKGVTGMTTKDEDEIAHIITANTHDDIYFFTNKGRVFRVKTYDLPEGSRQAKGQAVVNLINIEQDE
KLATILNLGKTNTSKFLLMVTNAGTIKKTKISEFENIRNSGKIAIKLDKNDSLKWVKPTSGSDHILLVSHEGKSIRFKEEDVRGTARDTMGVRGIELKSG
DYVVGMENFPSFEDVLIVMQNGLGKRTGVKEWPLQKRGGQGVKAAEVTP-KTGKIISCISVDEVDQIIITSKTAQVIKLPLKNIPQLGRATQGVILMRFA
NKDVAAVTC---
>tr|A0A0G1UE14|A0A0G1UE14_9BACT DNA topoisomerase (ATP-hydrolyzing) OS=Microgenomates (Amesbacteria) bacterium GW2011_GWA2_47_11 GN=UX78_C0014G0003 PE=4 SV=1
EEDLIPSEDTVVTVTATGYIKRQNPSVFRTQHRGGKGVTGQTVKEEDEISHILTANTHDDILFFTNLGRVFKVKAYDLPEGSRQAKGQAVVNLINLGSDE
KLQTILALGKGE-VKFLLMATQKGTIKKSKIADFDHIRTSGIIAVKLEPGDSLQWVKPTTGSDQILLVSYAGKSIRFREEDVRPTARDTMGVRGIDLKSG
DYVVGMEVFPGFEDVLIITEKGLGKRTSVKAWPLQKRGGQGVKAASLAA-KTGLIVSCIGVDEVDQVVLTSRTAQIIKLPLKNIPRLGRDTQGVILMRFS
QKDVAAVTC---
>tr|A0A0E9E364|A0A0E9E364_CHLTH DNA topoisomerase (ATP-hydrolyzing) OS=Chlamydia trachomatis GN=gyrA_1 PE=4 SV=1
TDEPIEKKQMVVHLTNLNTLYDTTLITARRGRGMKVK-----LGNNEQIIQTVKDSNLNNLLLFSSLGKVYNLALSNLTL----DCRTPIS-TILLAPDE
TITYIVSDTD--QGEEVLFVTQKGTVKKTLLREYNIKRTKGVSAIKLTDGDFIKRVMIVNNKDNLAITTKNGYVVIFPLT-INTQGRNTIGVRGITLRLG
DEVCDACVIRK-KELISVTEAGQVKKTDLDEFSVTSRAAKGAIIHKLNDE--DKLAGFASVR-DSKTVSVASTGAIIKISLNEIPTTSRATVGVKSINLK
DGYVTGLIV---
>tr|F4VHK0|F4VHK0_ECOLX DNA topoisomerase (ATP-hydrolyzing) OS=Escherichia coli H591 GN=ECPG_00851 PE=4 SV=1
LEDLITQEDVVVTLSHQGYVKYQPLSEYEAQRRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDE
RITAILPVTEFEEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTGVRGIRLGE-
DKVVSLIVPR-DGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTE-RNGLVVGAVQVDDCDQIMMITDAGTLVRTRVSEISIVGRNTQGVILIRTA
EDNVVGLQR---
>tr|A4P0W9|A4P0W9_HAEIF DNA topoisomerase (ATP-hydrolyzing) OS=Haemophilus influenzae 22.4-21 GN=CGSHiR3021_04427 PE=4 SV=1
LEDLIAQEDVVVTLSHEGYVKYQPLTDYEAQRRGGKGKSATKMKEEDFIEKLLVANTHDTILCFSSRGRLYWLKVYQLPQASRGARGRPIVNILPLQENE
RITAILPVSAYEEDKFVVMATAGGIVKKIALTEFSRPRSNGIIALNLRDEDELIGVDITDGSNEIMLFSSQGRVVRFAENAVRAMGRLATGVRGIKLALT
DKVVSLVVPK-EGAILTATQNGYGKRTQLSEYPTKSRNTKGVISIKVSE-RNGKVVAATQVEETDQIMLITDAGTLVRTRVSEVSIVGRNTQGVRLIRTA
DDHVVSLER---
>tr|A0A0M1JBY1|A0A0M1JBY1_9GAMM DNA topoisomerase (ATP-hydrolyzing) (Fragment) OS=Achromatium sp. WMS3 GN=TI05_13380 PE=4 SV=1
IEDLITPEDMVVTLSHAGYAKSQPVTQYQAQKRGGKGKVATTTKDEDFIDKLFIANTHDTILCFSSVGKVYWLKVHELPQAGRNARGRPIVNLLPLEANE
RINAVLPIHEYQEGIFVFMATSNGTVKKTPLLDFSRPLARGIIALNLRDNDKLIGVALTDGNQEIMLFASNGKVVRFPESQVRTVSRTASGVRGMKLAE-
AQVIALLIAT-PGSILMATANGYGKRTAIDQFTPHNRGGQGMIGIRTNE-RNGAQVGAILVQEDDEIMLISDGGTLVRTKVASVRLMGRATQGVRLINLT
EQKLAGLAR---
>tr|A0A0B8QM25|A0A0B8QM25_9VIBR DNA topoisomerase (ATP-hydrolyzing) OS=Vibrio sp. JCM 19241 GN=JCM19241_3371 PE=4 SV=1
MEELIAQEDVVVTLSHEGYVKYQILSDYEAQRRGGKGKSATKMKDEDYIERLLVANTHDNILCFSTRGKTYRLKVYQLPQASRTARGKPIVNILPLEEGE
RITAILPVSEFSEDKFIFMATADGTVKKTSLDQFSNVRSNGLIAVNLRDEDSLIGVDITSGEDDIMLFSKAGKVVRFNESQVRGMGRTAAGVRGIKLNG-
DQVVSLIVPH-EGDILTITENGYGKRTVLEEYPAKSRATQGVVSIKVSE-RNGSVVGAVQTEEGDEFMVITDGGTLVRSRVAEVSQVGRNTQGVTIIRTI
EDRVVALQR---
>tr|M4RPT8|M4RPT8_9ALTE DNA topoisomerase (ATP-hydrolyzing) OS=Paraglaciecola psychrophila 170 GN=C427_2529 PE=4 SV=1
IEDLIEREEVVVTLSHEGYVKYQKLNDYESQRRGGRGKSATKMKNEDFIEKLLVANTHDHILCFSTRGRLYWLKVYQLPLASRNARGRPIVNILPLEENE
RITAILPIQEFEEGKFVLMATANGTVKKTALTSYSRPRSNGIIAVNLNDGDELIGVDITHGDDDIMLFSDAGKVVRFNEKQLRPMGRTATGVRGIRLKD-
QKVISLIVPK-DGAILTATENGFGKRTPVSDYPAKSRATQGVVSIKVSE-RNGKVVGAVQVNDSDEIMLISDQGTLVRTRVEEVSTVGRNTQGVRLIRTI
EGRVVGLQR---
>tr|A0A090VD18|A0A090VD18_9FLAO DNA topoisomerase (ATP-hydrolyzing) OS=Algibacter lectus GN=JCM19300_704 PE=4 SV=1
IEDMIPNESVVITISHAGYIKRTSLTEYKTQHRGGVGQKASTTRNEDFLEHLFVGTNHQYMLFFTQKGKCFWMRVYEIPEGSKTSKGRAIQNLV-IEQDD
KVMAFICTQDLINSHYVIMATKKGQVKKTSLEQYSRPRTNGINAITIKDDDVLLEAKLTTGESQVMLALKSGKAIRFEEA-TRPMGRGASGVRGIRLQDE
DEVIGMIAVD--SNVLVVSENGYGKRSSLEDYRITNRGGKGVKTISITE-KTGNLVSIKNV-TDDDLMIINKSGVAIRLAVADLRVMGRATQGVKLINLK
GKDIAAVAK---
>tr|F3H376|F3H376_PSESX DNA topoisomerase (ATP-hydrolyzing) (Fragment) OS=Pseudomonas syringae Cit 7 GN=PSYCIT7_19571 PE=4 SV=1
LGDLITEEERVVTISHGGYAKTQPLAVYQAQRRGGKGKSATGIKDEDYIAHLLVANSHTTLLMFSSKGKVYWLKTYEIPEASRAARGRPLVNLLPLSDGE
YITTMLPVDLKKKAPFIFMSTANGTVKKTPLVAFSRQRSSGLIALELDEGDILISAAITDGEQEIMLFSDGGKVTRFKESDVRAMGRTARGVRGMRLPE-
QKLISMLIPE-GSQILTASERGYGKRTAISEFPEYKRGGQGVIAMVSNE-RNGRLVGAVQVLDGEEIMLISDQGTLVRTRVGEVSSLGRNPQGVTLIKLA
SDKLVGLER---
>tr|A0A0R2VWF9|A0A0R2VWF9_9GAMM DNA gyrase subunit A (Fragment) OS=SAR86 cluster bacterium BACL1 MAG-121128-bin56 GN=ABS13_08095 PE=4 SV=1
NEDLIPEETRVLTLSRSGYAKTQPLDEYREQRRGGVGKAGASVKEEDLIQNLYVLSSHSQLLCFTTKGKVFWLKVYEIPVATRTSKGRPLVNML-LDADE
TVTQILPVDEFSEEKYIFMATKNGIIKKTNLNLFHKKYNSGIKAIRLDDDDKLVGTVITNGDNDILLSSSSGKLIRFHES-VRPMGRTARGVKGISLKEG
MKVISLMI---SKTILCLSENGYGKKTRLEDFPSYNRGGQGVIALKTSD-RNGNMVSAVAV-DDDGIMLISDKGTLIRTAISQIPTLGRNTQGVKVITPK
DGKIEGVRI---
>tr|A0A0F9NZF9|A0A0F9NZF9_9ZZZZ Uncharacterized protein (Fragment) OS=marine sediment metagenome GN=LCGC14_1276920 PE=4 SV=1
LEDLITEEEMVVTLSHAGYAKTQQLDTYQAQKRGGKGKAATSMKDEDFIEHLFIANTHDTLLCFSSAGKVYWKKVYELPQGSRAARGKPIVNLLPLEEGE
KINAVLPIREFEADKFIFMATASGTVKKTPLVDYSRPRANGIIAVDLKDDDQLVGVAVTDGHSDVMMFSSTGKVIRFPETDVRSMGRVSRGVRGMRISE-
EKIISLIIAQ-EGAILTATEFGYGKRTNLAEYRVQGRGGQGIISIQTSA-RNGNVVGAVQVCEDNQIMLITNGGTLVRTPVKHVSLVGRNTQGVRLINLS
NDKLVGLER---
>tr|J9FAK7|J9FAK7_9ZZZZ DNA gyrase subunit A OS=gut metagenome GN=EVA_20423 PE=4 SV=1
KRDLIPRRDMVVTISRGGYIKSQELSDYNAQTRGGKGRKVQEMTKDDEVEELFIANTHDIILCFSTAGRVYPIDVFELPEGKSSARGRPIVNLL-LEDEE
KISFILPIQGYDDEHFVFMVTDRGIVKKTPLSAFRNARLKGLIATILEEGESLVGVAITNGQCDALVFSDAGKCVRFDEN-VRSMGRNSHGVRGIRLDDG
QKAIALIVCDNTRFVLTATENGYGKRTPLSEYSRHGRGTKGLISICTSE-RNGRVVSAVLT-EHDEVMMLSTGGKVVRTEAAQISVVGRNTQGVKLIDLG
EGDLASLRR---
>tr|C0X5K0|C0X5K0_ENTFL DNA gyrase C-terminal domain, beta-propeller (Fragment) OS=Enterococcus faecalis TX0104 GN=parC PE=4 SV=1
TAVLVAQEDVVVTVTHEGYIKRSSIRSYTASKPEEIG-----MKEGDFLLYAGEVNTLDHLLLVTNKGNMIYRPVHELPDLRWKEIGEHISQTILLAIDE
SIIAVYPYKE--PTKTFVFITKAGMIKQTKMADFEPWRTRPTSCMKLKSDDEITNVYLTNDLLDVFLVSNRGFGLRYPLY-VPVVGSKAAGVKSMNLKED
DYVVNGLLVHS-TPIVIVTQRGGVKRMLAQELTQLGRAKRGLMVLRELKKNPHRVVFMSEST-DLDLLVTTQKGTQEVIQSKNYPISERTS---------
NGFVIDEQK---
>tr|T0U5B3|T0U5B3_9ENTE Topoisomerase IV subunit A OS=Enterococcus sp. HSIEG1 GN=HSIEG1_279 PE=4 SV=1
TQVLVAQEDVVVTVTTDGYVKRSSLRSYGASKPEELG-----MKEGDALLYSGQASTLDHLLLVTNKGNVIYRPIHELPDLKWKDLGEHISQTVMLATEE
TILAVFTYQE--PQKNFVLISKNGMIKQTRMTEFEPWRTRPLTMMKLKDEDELVNVYLADQPLDVFLVSYRAFGLRYPLA-VPVVGPKAAGVKAMNLKED
DQIVNGLLVYS-TPVIMVTQRGAVKRMLAQEISQLGRAKRGLMVLRELKKNPHRIVYMGSGE-NQSLILTTQKGQMIEIETNQIPINDRTS---------
NGFVTDEKS---
>tr|E3ZQ20|E3ZQ20_LISSE DNA topoisomerase IV, A subunit (Fragment) OS=Listeria seeligeri FSL N1-067 GN=NT03LS_1565a PE=4 SV=1
TEVLVANEDVIVSVTKEGYVKRTSQRSYAASNGKELA-----MKEADHAIFIKKMNSLETLLLFTSKGNFIYRPVHELPDIRWKNLGDHVSHLASLSAGE
EIRSVIDIQT--EEKRFLFVTKNGMTKQSLITNYKPQRYKSMMGIKLKDDDELLSVHLIDG-EDIFLATKNGYGLRYPIA-IPESGARTAGVKAINLKQD
DTVIGGVVLTQ-RHILLATQRGSLKQMKASEFEPISRAKRGLLMLRELKNNPHRFIGITLAN-KDHLFIETKTEQIVEVDVANLRVTDRYS---------
NGFVLDETM---
>tr|W7CSS4|W7CSS4_BROTH DNA topoisomerase IV subunit A OS=Brochothrix thermosphacta DSM 20171 = FSL F6-1036 GN=BTHER_07061 PE=4 SV=1
RTVLVASEEVMVTVSEQGYVKRSGLRSFSASNGAELG-----MKENDHAVFAQQMNTMDFVLLFTDKGNYIYRPVHELTDIRWKDLGEHISHLA-ADSSE
RVIAVLPVKE--ESTSVVFTTANGMIKRSALNLYNPQRYRSLAAVKLKAGDEVINVFLVQD-DTVTMTTNFGYNLTFAIT-VPVGNVRTSGVKAINLKKE
DKVIGCVKLEK-HDLLLVTQRGSVKRFSQRHLEVQNRALRGLLMLRELKAKPHRYIAMMSVT-DDKVNVLTDKGEVTVVEVKTNSVSDRYS---------
NGFILDENE---
>tr|M5MVR2|M5MVR2_STREE DNA topoisomerase IV subunit A domain protein (Fragment) OS=Streptococcus pneumoniae PNI0446 GN=PNI0446_01490 PE=4 SV=1
TASLIAEEDTYVSVTKAGYIKRTSPRSFAASTLEEIG-----KRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELADIRWKDIGEHLSQTITFETNE
EILYVEVLDQ--DATTYFAVTRLGQIKRVERKEFTPWRTKSVKYAKLKDDDQIVAVAPIK-LDDVVLVSQNGYALRFNIE-VPVVGAKAAGVKAMNLKED
DVLQSGFICNT-SSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKNKPHRVFLAGAVAEQT-LLVQSNKGTIYESRLQDLNLSERTS---------
NGFISDTIS---
>tr|A0A0E9GBX6|A0A0E9GBX6_CHLTH DNA gyrase subunit A OS=Chlamydia trachomatis GN=gyrA_6 PE=4 SV=1
TASLIVEEDTIVSLTRGGYIKRTSLRSFNASSLDELG-----KRDDDDLVFMAQAKTTQHLLIFTNQGNVIYRPIHELTDIRWKDVGEHLSQTITLSADE
EVLYAEILDE--P-GVYFAATRLGQIKRFERKEFAPWRTKSVKFAKLKDEDSIVAVAPIL-LDDIMMVTQNGYALRFNID-VPIVGAKAAGVKAINLKDS
DLLQAAFIANT-KSLYILTQRGSLKRMAVEDIPLAKRAGRGLQILRELKAKPHRVFMAGPVLLQQILQIMSKTGDVTEVNLANLTLSERTS---------
NGFISDKIS---
>tr|W4QEN7|W4QEN7_9BACI DNA topoisomerase (ATP-hydrolyzing) OS=Bacillus hemicellulosilyticus JCM 9152 GN=JCM9152_1953 PE=4 SV=1
MDVLIASEDVMVSVTHEGYVKRASLRSYTASNGELPG-----MKEGDLLLGYYEMNTTDTLVLFTKLGNYLYIPVHELPDIRWKDMGQHVANIV-IDRED
EIIAAMPIKE--EQQSLLFVTKNGMAKRSQLSLYQAQRYKPLMAIKLKDHDEVVSVFKTNGEQELFIATAQGYGLWFSES-VNAVGQRAAGVKGINLKED
DYVVDANMFSL-VEFLIVTHRGAAKKVSISEFDKSTRAKRGLMILRELKSNPHRVIACKKIS-NEIYQLLTDKGHIESLESKSIRKSDRYS---------
NGFIVDTNH---
>tr|K0NAP8|K0NAP8_LACCA DNA topoisomerase 4 subunit A OS=Lactobacillus casei W56 GN=parC PE=4 SV=1
TTVTVADETVMVQVSRDGYVKRSSLRSYQAVDPADNG-----LKANDLAIFTGELSTLQHLYIVTNAGNVIYRPVHEISDARWKDTGEHLSQTV-LGTDE
KVLAVFAFDQ--GAGSFVLGSSDGYIKQTALSDLQPQRTKPMMAMKLKDPA-IVTNAYFTTQQDVFVVSRHAYGLTFPLS-VSTVGARATGVKSMDLKPD
DEVVNFILVKD-AKVGILTQRGAFKKMALSEVGEMSRARRGLLVLRELKRDPHRIVAMMSVD--TRLNVLTDTGKVTTLNPAQHPAGDRYS---------
NGFVIDTDV---
>tr|F4BRL5|F4BRL5_CARS1 DNA topoisomerase 4 subunit A OS=Carnobacterium sp. (strain 17-4) GN=parC1 PE=4 SV=1
TEVLIASEEVIVSVTKEGYIKRTSLRSYGASKPNELG-----IKEGDYPLYIQQLNTLNHLLIFTSKGNIIYRPVNEISDLRWKDMGEHLSQNIAFSADE
TVVKVFGITQ--PQATFTFITKEGYIKQTAVSEYVIGRNKSFSAIKLKTADELINIIHTENLKDVFLVTHRGFGLRYSLE-VPVVGSKAAGVKSINLKEG
DYVINGVLIDVKKELMILTHRGSIKKMNILDFESLGRAKRGLLLLRELKKNPHRVAFAFEVS-EDHYVILTSKGKEIPLSSASYAISDRYS---------
NGFILDEVA---
>tr|A0A0D0H2Q0|A0A0D0H2Q0_LACBR DNA topoisomerase (ATP-hydrolyzing) OS=Lactobacillus brevis GN=N624_1885 PE=4 SV=1
TTVTVADEDVVVLVSHDGYLKRSGVRSYTASDPTDNG-----LKDGDYPIFMQKLSTLNHLMMFTSKGNLIYRPVHEISDVKWKETGEHISQTI-LAADE
EIVATFAFKT--EPGRFLIATSDGYIKQTAFADLTPGRTRAAVYEKLKTAARVVAVKYLTEEQGILLISKNGYALRYPVD-VSVNGARTTGVRSMDLRDD
DEVVNLALVTD--TIALITQRGAFKRLAMKELSVTSRARRGVIVLRELKRDPHRIVDFMTIP-NPPLEIMTSRERTHDVMPTDHPLSGRYS---------
NGFVIDTDV---
>tr|R6ULS4|R6ULS4_9FIRM DNA topoisomerase IV A subunit OS=Erysipelotrichaceae bacterium CAG:64 GN=BN746_03497 PE=4 SV=1
KLAMINSEQVMFTISRDGYFKRVSMRSYGASRDDMTG-----LKEGDHLVGYGEVNTLDHVLFFTTQGTYGYTPVYEVEESRWKEIGSHINSTI-ISGEE
KITDAFVLRS--TNAYMISVTKNGLVKKTAVREYEVSRNKTMSNMKLLDGA-VVKTMV--AYDEILIASKNGFVSRYPVS-IPETSPRSKGVKAMNLVLD
EIVSACISHGDASQLIVFTDQCQMKRIKLSDVDVTGRPTKGSMICKKVKSKPYQIAHIALHELNDELVIINEETQKILAKDISMSKDATFSSP---LHTT
QDYFLRTL----
>tr|A0A0E9F3N7|A0A0E9F3N7_CHLTH DNA gyrase subunit A OS=Chlamydia trachomatis GN=gyrA_10 PE=4 SV=1
MDLQIPDDPCVVVLSSNGGLARVEGSDPL---------EPGPRASHDGWIAQLSSTARSQIAVVTADGVAHRMEVVDLPALPRFDAATPASLLL-TDSPA
IGLLDPASD-----QVYAMGTAHGTVKRLKPDV-LA---DEWEVITLDDGDRLVGFGPCA-DYDLVFVSTDAQLLRTPAS-VRPQGRTAGGMAGMKLNDG
AHALGFWALPVAEGALPGTGQTTAKVTPLELYPVKGRGGQGVRAQRFLRGE-DRIDLAWVGD--RQPRGASADGSPVDLPDVD----RRDGSGTPVV---
----LPITL---
>tr|A0A0K2RD91|A0A0K2RD91_9MICC DNA topoisomerase (ATP-hydrolyzing) OS=Arthrobacter sp. Hiyo8 GN=AHiyo8_10960 PE=4 SV=1
LPLEIPDDPCWALLSASGQIARTSNQEPLA--------ESGPRSKHDVYRSVVKTTARGEIGAVTSQGRMLRVQVMDMPALPAMSGGVAAKDFI-LLKGE
SLVAFVPLD-----AVLAIGTAQGVVKRVQPDYPLN---EDWEIIALKDKDTVVGVEPAQDDVDLVFVTRLAQLLRFSAS-VRPQGRTAGGMAGIKLGVG
DDVIHFGTVRASNGALPGTAPGTAKITPFEEYPAKGRATGGVRAHRFLKGE-DTLLLGWAGH--GPAKASSSAGVARALPQEH----RRDGSGVPLS---
----QPVDA---
>tr|W4TDT8|W4TDT8_PROAA Topoisomerase IV subunit A OS=Propionibacterium acnes JCM 18909 GN=JCM18909_165 PE=4 SV=1
APLEVPDDPCWVLLSATGLLARIDTADGLP--------SGGDRATHDVIISSARTTARSDFGIITSAGRLVRVHAVELASLPITAGGTPLADLV-LEKGE
RALAVTSLS----GPSLALGTRNGIVKRVNPEL-LG---ESWEVIGLKDGDEVVGAVEMGDDLELCFVTQGAALLHFPAS-VRPQGRSGGGVAGIKAKD-
-PVIFFGAAPRSSPAAAGKEPGSIKLTPLDQYPPKGRATGGMRCQRFLKGE-AALVFAWIGP--DPAVACAASGMPIEL---------RDGSGDQGR---
----QPILA---
>tr|W4UDZ4|W4UDZ4_PROAA Topoisomerase IV subunit A OS=Propionibacterium acnes JCM 18920 GN=JCM18920_729 PE=4 SV=1
APLEVPDDPCWVLLSATGLLARIDTADGLP--------SGGDRATHDVIISSARTTARGDFGIITSAGRLVRVHAVELASLPITAGGTPLADLV-LEKGE
RALAVTSLS----GPSLALGTRNGIVKRVNPEL-LG---ESWEVIGLKDGDEVVGAVEMGDDLELCFVTQGAALLHFPAS-VRPQGRSGGGVAGIKAKD-
-PVIFFGAAPRSSPAAAGKEPGSIKLTPFDQYPPKGRATGGMRCQRFLKGE-TALVFAWIGP--DRPWPVPRPGCLSNCQHLIVNRFWQSGVAVTGL---
----TRVIR---
>tr|W7T5A7|W7T5A7_9PSEU DNA topoisomerase (ATP-hydrolyzing) OS=Kutzneria sp. 744 GN=KUTG_05485 PE=4 SV=1
GPLEVADDPCQVLLSATSLVARTAAESEEASEA----RRRNGRARNDAVAAVVHTTARGQILVVTSKGRAFKTDVLPLPVLPEQVGGMAASELV-LDKGE
RVITIAPLTD---SPGLAMGTAQGVVKVCSPEWPVR---DEFEVISLKDGDEIVGATWLSDAETLVFVSSDSSLLRYEAS-VRPQGLKGGGMAGIKLAGD
AHTVFFAAVRT-----VTATGNSVKVTPFAEYPPKGRATGGVRSHRFLKGE-AGLRLAWIGS--RPA-GSTDTGSSVELPEVD----RRDGSGHPHP---
----GPDV----
>tr|F0QQ06|F0QQ06_MYCSL DNA gyrase C-terminal domain protein OS=Mycoplasma suis (strain Illinois) GN=gyrA2 PE=4 SV=1
---MEGINMLLLAFSRRNFIVSLPYAEFNLGEKIEKGINLSGLITDDMIRDVIALSSNDDLLIITNKGKIYRTQANQLLRVKKENKLLQLQHVSSFRDDE
QIIKIINVEPYLDSSFLFLASKDGMIKKIKMMNFQNASKSGGIVMGLQGEDEVVSALIVRDADEILLTSSFGRVVRFKSIDLRDVGKTAMGVRGIKLVNS
KGEEGELISASSKEVFVLTNLGKGKWVHIDHFRMTSRGVAGVLSQK----GYGFSFTININNPLEEIFMLTNLGKVSRIPVNAVSQRGRATSGVSIMKLN
HSNIVHCFKFI-
>tr|I7BB22|I7BB22_MYCHA DNA gyrase C-terminal domain protein OS=Mycoplasma haemolamae (strain Purdue) GN=MHLP_04575 PE=4 SV=1
---------------------------------------------------MIVAPYDAELIAVTNAGKVFKMSTRELI-ISPG--LLSVQNLGYLDNDE
HLVKFIYMDEYHKDICLLFCTKYGIVKKVPIAEFKHVRAIGKIAILLKGNDSVRFVNKVSESDEILLASEEGLAVRFQSNELRKTGRLSSGVKGIKLTPD
TGEISSS-TT--LKVFVVDEQGTGKLTDIDKFKLTVKAVRGVIAYKLN-DSD-KLIACTLIKGDEEIVFLTNKHNVLRLPVSEIAERSRICGGVRLIKLD
EG-VMLCAKSA-
>tr|X0XX91|X0XX91_9ZZZZ Uncharacterized protein (Fragment) OS=marine sediment metagenome GN=S01H1_66057 PE=4 SV=1
---------------------RLPINTYRQQRRGGKGVIAAGKNDEDFVEEILVANTHDYILFFTNKGKVHWQKVYNLPEASRTARGSAIANMLQLGKDE
RIQAYVPVKKFKD-GFLFMATSKGVVKKTALEQFSRPRRGGIIALSLDDDDELIGVRMTDGKQQMILATRKGFAARFREADVRAMGRTAHGVRGIRLRQT
DKVVSLVVADDNQSLLTVTKKGFGKQTTVSDYRLIGRGGSGVINMKCT-DRNGMIVSVHSVIPGDEVMLISQK---------------------------
------------
>tr|A0A0G0XAH1|A0A0G0XAH1_9BACT Gyrase subunit A protein OS=candidate division WWE3 bacterium GW2011_GWC1_41_7 GN=UU77_C0003G0010 PE=4 SV=1
------------------------------------------MREEDQAATIRICDTHDYAFFFTNTGKVYKLRIWDIPESSRTSKGTALVNFLNISQSE
KVQTFLNINA-NGKGFVSFVTEKGQVKKTSLEEFANIRSSGILAIKLSGDDYLTWVGLTEGSDDLLLTTSMGQSIRFSEKDVRAMGRAAAGVTGIRLSKK
DDYVVGTVIIPHIALMVVTGKGYGKKTPVSEYKVQNRGGSGILTYKVT-DKTGKLVTAKEYYPDVELLIATVSGKIIRLSTEQVPTLGRATIGVRLIRLG
EGHVTSVASLE-
>tr|X1H029|X1H029_9ZZZZ Uncharacterized protein (Fragment) OS=marine sediment metagenome GN=S03H2_50186 PE=4 SV=1
----------------------------------------MNLKEDDFVEHLFISSTHQFMLFFTNRGKVYKIKTYGLPTGGRTSKGKSIRNFFNFSYNE
RIEMVITTDNFKFKEFIMMVTKNGLIKKTELSQYKNASRGGLIAINLKKKDEIVGVLKIKPKEEVIIISANGKGIRFGENQIRATSRNTMGVRAMRLNKG
DRILGMGIAIDDTDLLLITKNGYGKRTAISEYKVQRRGGKGVIAIKTD-SKTGNLIGCKVVRKNNELVLISNDGTLIRVSVDSIRKVG------------
------------
>tr|A0A0B3B272|A0A0B3B272_9ARCH DNA gyrase subunit A OS=archaeon GW2011_AR19 GN=gyrA PE=4 SV=1
--------------------------------------------------------MSKITRSNTTRGRVLWLKAYDIPASEKYSKGRAITNLMELK-DE
KITNVISVKNFDD--SLFMATKKGVVKRISLKHFSKPRASGIKAINFPPGDILIGVEVVKPKQEVLLATKKGKAIRFNAEDVREMGRASYGVTGIKLNGN
DEVVSLEILD-TKAILTITKKGYGKRSLVEDYRKTSRAGKGVINLKIT-DKTGEIVTTASVNDKDSIIITTAKGIVIRTSLENIRVMGRATQGVRIVKLQ
QGYVTDLVKFI-
>tr|A0A0F3R864|A0A0F3R864_RICAM DNA gyrase C-terminal domain, beta-propeller family protein OS=Candidatus Rickettsia amblyommii str. Darkwater GN=RAMDARK_1787 
------------------------------------------------------------MLFFSNIGQVYSLKLYKLPLSNPQGKGRPMVNILPLKANE
HIANIMPLPEERDNLNIMFATAKGNIRRSDLLDFKKLQSNGKIAIRLDEDDKLIDVKLCKEDEHILLATKAGKALRFPVESLRVKSRTSDGVRGMKLAKE
DSVISMTVLKGIEFILTVTENGFGKRSSAYGYRITDRGGSGIINMDIN-DKTGLVVGVMPVKMDDELMLITNSGKLIRCKLESVRITGRNTSGVILFKLD
DGKVVSVSLIA-
>tr|T0LJ50|T0LJ50_9EURY Uncharacterized protein (Fragment) OS=Thermoplasmatales archaeon E-plasma GN=AMDU2_EPLC00017G0001 PE=4 SV=1
---------------------------------------------EDVIRSAVSGNSHDDILYFTDLGRVFAGKVYEIEKRARTSNGISVQSFLKLQDKE
TVRQIM-IPSFTEGSHIFIATRAGYIKKIDSDQLQNIRSTGIRIVTLEEGDTVVAIEVIHEGERIAVVSEDAKIATFDPIHVRSMGRQARGVRSMRLPRG
RSVLTAFAVSDADYIMSVSEKGIGKRTRSSEFPVHNRGTSGVFIFREN-KRTGKLVSAISVKEDDEVLILTRGEKSIRIAVKDIREISRVTSGVKLVNLD
DDIVVSVTRI--
>tr|K1XQW6|K1XQW6_9BACT DNA gyrase subunit A (Fragment) OS=uncultured bacterium (gcode 4) GN=ACD_83C00230G0001 PE=4 SV=1
------------------------------------------------VEELIVTRTHDTILFFTDLGKIFKSKIYEIPAVSRQSKGVALQNIVSISSDE
HVTAILTVNKEDEHPYIMMGTESGAVKKTSLKSFKNVRTTGIAAITLKTGDKLKWAKLTSSDDIIIEVSKSGQCIVFSEKDIRPMGRSASGVRGMRLRQN
DKVITLTMVPKDYELIVVLENGFGKRSKLSLFDIQKRGGIGIKAANVT-SKTGSVVDARIVHDAFNALLVSKLGIVIRMGLSDIKLLGRVTQGVTLMRLG
KGKVASVAIVP-
>tr|A0A0G0UTV2|A0A0G0UTV2_9BACT Gyrase subunit A protein (Fragment) OS=Microgenomates (Woesebacteria) bacterium GW2011_GWD1_41_12 GN=UU39_C0003G0001 PE=4 SV=1
-------------------------------------------KEEDEIEHLVNATTHDTILFFTNKGRVFGIKAWEIPESARQAKGQALVNLLNLEQGE
EIRSILPTMK-LGIKNLVMATKTGIIKKTQISQFENLRASGLIAIKLKDDDQLVSVHPTTGDDHIILLTRDAKSIRFPEANARPMGRATTGVTGIKLEKG
DELIGMEVFPSKRDILTFAEKGLGKRTQIHHFPVQKRAGKGVKAAVVT-DKTGFLKTAIMVTQVIDVVITSKMGQVIKLPLKNIPQLGRATQGVILMRFA
NKDSVAAAAVL-
>tr|K2DFQ8|K2DFQ8_9BACT Uncharacterized protein (Fragment) OS=uncultured bacterium (gcode 4) GN=ACD_38C00046G0001 PE=4 SV=1
---LVADEQTIITVTQGGYVKRQLPGTFRTQARGGKGVSGITTKEEDAVSHIFYTRTLDNLLFFTDKGRVFQIKVWEIPETSRVAKGQAIVNLINVEQGE
KMTAILTHRS-DKFKFLFMCTKQGNVKKTPIEEYANIRKNGLISIKLDSGDELGWVVPTSGNDDTVIVSYRGQSIRFKEALVRPTHRDTSGVRGITLEKD
DEVVSMNLVDDPLHVLVVMENGLGKKTPISAWKTQGRGGSGIKAAQVT-EKTGKIVTAQLINPSHELVLTSNKGQLIKLNIKDIPTLQRQTQGVILMRVR
PGKVAAATVVG-
>tr|A0A0G0KDX9|A0A0G0KDX9_9BACT Gyrase subunit A protein (Fragment) OS=Microgenomates (Daviesbacteria) bacterium GW2011_GWF2_38_6 GN=US99_C0050G0001 PE=4 SV=1
---------------------------FRVQQRGGKGVMGISTKETDAVSHIFYTQTHDNILFFTDKGRVFQIKVWEIPETQRAAKGQAIVNLINVEQGE
KVTANLTTRQ-ESAKYFFMCTQKGTVKKTSLEEYANIRKNGLVAIKLDPKDELGWVCPTSGKDDLIIVSRQGKSIRFSETQVKPTHRDTSGVRGIRLSKD
DEVVSINIVENEDALLVIMENGLGKKTLFSSWSKQGRGGQGVKAAQVT-AKTGRIVTTQVVNKNTDLVLTSTKGQLIKMDLKQVPTLQRQTQGVILMRVR
VGKVVAATVVA-
>tr|A0A0E8TRB4|A0A0E8TRB4_STREE DNA gyrase subunit A OS=Streptococcus pneumoniae GN=gyrA_3 PE=4 SV=1
---LIPEQNIAITLTHNGYIKRLPASTYKTQNRGGRGVQGMGTNDDDFVEHLLTTSTHDHILFFTNKGKVYRTKGYEIPEYSRTAKGIPIINLLGVDKGE
WINAIIPIREFGDDEFLFFTTKQGISKRTPLSSFANIRTNGLIAISLREEDEVISVRLTSGDKDIIVGTSNGMLIRFNEQDVRSMGRNAAGVKAITLGDE
DQVVGMEIVEE-VNVLIVTKNGYGKRTPIDEYRLQSRGGKGLKTCNIT-DKNGKLVAVKSVTGEEDIMLITAAGVIIRMPVDQISQMGRNTQGVRLIRLE
EDEVATVAKAQ-
>tr|R7M5F1|R7M5F1_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:914 GN=BN809_00967 PE=4 SV=1
---LIPEENLVITLTKNGYIKRLPVDTYKIQNRGGVGIKGMSTNEDDFVEHIINTTTHDYVLFFTNKAKVYRLKGYEIPEFSRQSKGLPIINLLSLEKGE
YVTALVNGNINDNCKYFVFATKMGLVKRTEISEFYNIRNNGKKFITLRDDDDLISVKKTDGTYDILMASSNGRLVRFPENLVRVMGRGASGVRGINLDDG
-ILVGMEVANS-IDVLVVTEKGYGKKTPISEYRITNRGGKGVKTLNIT-DKNGTITSFKAVDKDKDLIIITNEGIIIRIDINSISMMSRVTQGVRLINLR
ENVVSSISVVD-
>tr|A0A081D494|A0A081D494_9MOLU DNA gyrase alpha subunit (Fragment) OS='Chrysanthemum coronarium' phytoplasma GN=gyrA PE=4 SV=1
---LIEEKPIIITITNKGYIKSMDIDTYKQQKRGGQGVSGMKIYEEDFIEHLAITSTHDYHLFFTNKGKVYQLKGYEIPLGQRQSKGSHLVNFLPFEKDE
FLTSFTSVKN-QSQDYLFFATKKGIVKKTPLKEYSHISKRGLIAIRLKENDEVLTVNKTTGTKNIILASNNGNAICFCETKIKSISRNSMGVIGMRLGSD
EFLVGAALFDTDQNILVMTENGFGKITNVNQYRIQERSGKGSKTIKVN-DQKGRLITLQVVLPTDDLIVSSDKGQVVRVAIDQITKTNKATQGTRIIKLK
TGKAVSVAVVK-
>tr|A0A0J7LDP4|A0A0J7LDP4_STAAU DNA gyrase subunit A (Fragment) OS=Staphylococcus aureus subsp. aureus GN=OO23_11455 PE=4 SV=1
---LIPEEQIVITLSHNNYIKRLPVSTYRAQNRGGRGVQGMNTLEEDFVSQLVTLSTHDHVLFFTNKGRVYKLKGYEVPELSRQSKGIPVVNAIELENDE
VISTMIAVKDESEDNFLVFATKRGVVKRSALSNFSRINRNGKIAISFREDDELIAVRLTSGQEDILIGTSHASLIRFPESTLRPLGRTATGVKGITLREG
DEVVGLDVAHA-DEVLVVTENGYGKRTPVNDYRLSNRGGKGIKTATIT-ERNGNVVCITTVTGEEDLMIVTNAGVIIRLDVADISQNGRAAQGVRLIRLG
DDFVSTVAKVK-
>tr|T0N9W3|T0N9W3_9CLOT Uncharacterized protein OS=Clostridium sp. BL8 GN=M918_23960 PE=4 SV=1
---LIDEEDVVITLTHTGYIKRLPVDTYNAQKRGGRGIQGVNAKENDFVEHVLITPTLNSILFFTNRGKAYKLKAYEIPEGSRTSKGTNIVNILPLEAGE
SIQAVISLRTFDKDNYLVMGTKEGIVKKTSLDKYEHIRKNGLNAINLRENDELIGVRITTGNSEIVFVTKCGYSIRFSEKDVREMGRTATGVKAITLRED
DIAVSMIIAKPNEELLVISEKGFGKRTDISEYTLQRRGGKGLKTYRVT-EKTGRLVGARVVRDLDEMMLINSDGIIIRINVSDISTTSRNAMGVTLMKTG
EDNIVAIAKIN-
>tr|H5TUE3|H5TUE3_9ACTN DNA gyrase subunit A (Fragment) OS=Gordonia otitidis NBRC 100426 GN=gyrA PE=4 SV=1
---LIAREDVVVTITETGYAKRTKTDLYRSQRRGGKGVQGAGLKQDDIVKHFFVSSTHDWILFFTTKGRVYRAKAYELPEANRTARGQHVANLLAFQPEE
RIAQVIQLKTYQDAPYLVLATRNGLVKKSKLEDFDSNRSGGIAAINLRGEDELVGAQLCSSDDDLLLVSQKGQSIRFHADTLRPMGRQTSGVQGMRFNGD
DELLSLNVVREGTYLLVATSGGYAKRTPMDDYPVQGRGGKGVLTIQHD-RRRGELIGAIIVDDDSELYAITSGGGVIRTAAKQVRKAGRQTKGVRLMNLD
EGTVIAIARNA-
>tr|R7BW94|R7BW94_9FIRM DNA gyrase subunit A OS=Firmicutes bacterium CAG:270 GN=BN579_01083 PE=4 SV=1
---LIPRENTVITMTKLGYIKRMTVDNFKSQNRGGKGIKGMQTIDEDYIEELFMTTTHHYIMFFTNTGRVYRLKAYEIPESGRTARGSAIVNLLQLQPGE
KITAVIPLADYEEGKYLLMATKYGVVKKSSIMEYANIRKTGLAAITLKDDDQLIEVKYTEDDEDVFLVTKNGQCIRFHESDVRCIGRTSMGVRGINLTGD
DEVIGMQLDSQGEALLIVSANGMGKRTLTSEFTAQHRGGKGIKCYKIT-EKTGDVVGVKAVNDDNEIMMITTGGIIIRTAVASISMLGRNTSGVKVMNVG
ENEVASIAKVR-
>tr|T1A347|T1A347_9ZZZZ DNA gyrase subunit A (Fragment) OS=mine drainage metagenome GN=B2A_06923 PE=4 SV=1
-----------------------PLDQYRRQRRGGRGLGQIETKEEDYVIRTFVTRTHDDVLFFTNLGRVYRLKAYELPEGSRQSKGKAVVNLLALKDGE
RVQTLLPIHDLAGAGSLFFATRRGLVKRTALGQFQNIRTSGIQAILLEEGDELVDVQVADEASEILLATASGQLVRFALGEVRPMGRATYGVIGVRLSEE
TDDVAMAPVS--PTLLSLTSTGYGKQTPVAEYRKTARGAKGVRTIKTG-DRNGSVVAVLPATDASELLVTTRTGVTIRMTVKGIRTQSRNTLGVRVIRLD
EGEVRDAIVLP-
>tr|T0YX31|T0YX31_9ZZZZ DNA gyrase, A subunit (Fragment) OS=mine drainage metagenome GN=B1B_15047 PE=4 SV=1
--------------------------------------------------------THDDVLFFTNQGRVYRLKAYELPEMGRHAKGKAIVNLLPLKAGE
RIQTELPVRGLSGPGTLVFATARGLVKRTELSRYQNIRVTGIQAILLEEGDELVDVL-TDGGSEVLLATREGQVVRFAERRVRTTGRATYGVRGLKLKG-
REDVAMTPVS--PSLLTVTSTGFGKRSPVEDYRLTGRGASGVIGIKTG-GRNGHVVTVLPVTGDDEVLLTTQKGITLRAPVGQVREQSRNTLGVILIRVE
PGEVMAAVRLV-
>tr|A0A023CYV5|A0A023CYV5_9LACO DNA gyrase subunit A OS=Lactobacillus sucicola DSM 21376 = JCM 15457 GN=JCM15457_1961 PE=4 SV=1
---MIEEEEVVVTLTHNGYVKRLPTSEFKAQRRGGRGVQGMGVHDDDFIEHLITTSTHEGILFFTNMGKVYRMKGYEIPEYGRTAKGIPVINLLGIDSGE
KIQAVINVSKEGQNNYLFFTTRQGIVKRTAVEEFSNIRSNGLKAITLKEGDELIGVQITNDERNIIIGTHLGYAVSFAEKAVRSMGRSAAGVRGIRLRED
DYVVGADILYP-SRVFVISEKGFGKQTAAADYPIKGRGGKGIKTANIT-KKNGPLAGLTTVLGGEDIMLITDKGVMIRFGIESVSQTGRATLGVHLIKVD
ADVVSTMAKVE-
>tr|W4L713|W4L713_9DELT Uncharacterized protein (Fragment) OS=Candidatus Entotheonella sp. TSY2 GN=ETSY2_50685 PE=4 SV=1
------EEDMVVTKSNTGYLKRQSLSLYQSQRRGGKGKMAMQTREEDFVEQLFIASTHDFLLFFTNIGKVHWLKVYRIPQAGRVARGKAAVNFLQLQPDE
KISTVVPIRRFEVERYLIMATKKGIVKKTELTAYGNPRQTGIIALTLDEGDELIGVGVTSSDQEIFLGTKNGLSIRFSEDDVRSIGRTGRGVIGIRLDDD
DEVVGMAVLSPEASILTVSEGGYGKRTHESEYRTQSRGGRGLINLRVT-PKTGRVIGVRQVFESDDVMLMSDQGNLVRIEVSEVNEIGRNTQGVRLISLN
EDRLVGVVRIE-
>tr|A0A0E9F116|A0A0E9F116_CHLTH DNA gyrase subunit A OS=Chlamydia trachomatis GN=gyrA_9 PE=4 SV=1
---IIKEEDVIITLTQSGYIKRMPEGTYKPQKRGGRGISATTPKDGDFVSDLFITSSHESILFFTTRGRVYRLKAYEIPESSRQSKGTQIRNLLNLEQDE
SVESIIHVKDFDSNLNIVMATKSGIVKRTSFEEFQNIRKSGLIAITLKDGDSIVSTRITTGEEDIMLVTKDGMSIRFKETDIRKMARTAMGVKGISLNDD
DEVVSMEIASDDKLMLVISEKGYGKLTPMSEYKVQNRAGKGIITYKVK-SKTGKLVSAKIMESNDDIMMITSNGIIIRIQIDGISVMGRSTSGVKLMNIT
DSVV-AVAKYI-
>tr|U5NBX2|U5NBX2_9MOLU Uncharacterized protein OS=Mycoplasma parvum str. Indiana GN=PRV_00175 PE=4 SV=1
---------MLVIFTKLEKIFSIPEEKFNIGERKGEGINLKKYLQGDIVKDIIRTSEESDLLIFTAFGRVYRINSNKVQVLR--SKKVELQDVEPFPSID
KVVRIISADQYQNNPFAFLGTKEGMVKKMFLGEFQSVRRSGAKIISLRGDDDLLDVKIIGKDDEIFLTSTSGHLVRFKSSEVREMGREAIGVEGINLSNK
KDLNFQVISISCEEIFTLTRKGKSKYTKLDEYKLTGRGRKGMYAYKFK-EKNGTCFAISVFNTSEFLFLITSSGKVVRLRADAISSRNRASAGVGIIRLD
KKQVVHCFKYM-
>tr|X0RUL1|X0RUL1_9ZZZZ Uncharacterized protein (Fragment) OS=marine sediment metagenome GN=S01H1_17490 PE=4 SV=1
-------------------------------------------------------------------------RAYQIPEGGRTSRGVAAINLLGIEKGE
HITTLIPIESEDNEKSLFMATKKGKIKKASLSLFSNLRNIGIIALRLLPEDELIGVRLAEDEEHVILTTKHGKSIRFSGNPIRSIGRTSLGVKGIVLQPE
DFLVNISLVPP-KYLLLVTEKGYAKRTDLKKFRESNRGGQGSKSIKIT-KERGLVVDVKVVSEEDELVLISQNGIVIRVPVKEIRHTGRYTQGVKVMNLV
PEKVASVALVS-
>tr|V4VZH4|V4VZH4_9ROSI Uncharacterized protein (Fragment) OS=Citrus clementina GN=CICLE_v10017460mg PE=4 SV=1
-----------------------------------------------------------------DRGIVYSARAYKIPECTRNAAGTPLVQILSLSDGE
RITSIIPVSEFAGDQFLVMLTMNGYIKKVSLNLFSSIRTTGIIAIQLVPGDELKWVRCCTNDDLVAMASQNGMVILSSCDIIRSLSRNTRGSVAMRLKDG
DKMASMDIIPAAPWLLFVSESGHGKRVPLSSFRKLPLNRVGLIGYKFS-AEDGNPMSLIAKDGESDVVLVSQSGTVNRIKVRDISIQARYARGVILMRLE
LSKSASLISVT-
>tr|U1PZI3|U1PZI3_9EURY Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit (Fragment) OS=Haloquadratum sp. J07HQX50 GN=J07HQX50_0
--------DVVVVVSEQDYIKRMPLDRFRSQNRGGKGIIGASLKDSDQISSVYVANTHDYLLYFTTHGKVYQLKTYQIPEMSRTARGKSAVNILELDEDE
QITAVVNTADAEQDRYLTMATKNGYVKRTKVGEFQNIHQTGIIAVNLSADDKLVDVEVTSGKRDLLLATRSGMAIRFSESEVRPMGRTARGVRGIKLENN
DTVAALAAVRETEWVLTVTENGYGKRTDVQQYRRQSRNGKGLIDIKTN-ERNGKVCELETVGTHDNVFVMSEQGQILRTAVDEISTVSRNTMGVIIMRLD
NSAVSSVDVQE-
>tr|A2I989|A2I989_9PROT DNA gyrase subunit A (Fragment) OS=Arcobacter cryaerophilus PE=4 SV=1
---LIPNEPMVVTITHNGYVKRVPIKSYERQKRGGKGKVAVTTHDDDFIERFFVSNTHDTLMFVTNMGQLYWLKVYKIPEGSRTAKGKAVVNLINLRPDE
KIMAIIPTPDFDESKSLVFFTRNGIIKRTSLNEFSNIRSNGVRAIVLDDADEIVTAIADVQTQYIMIFTSLGQCIRFELEKTRDQGRSTRGVRGIKFKID
TDFVDADVIDSEQEILTVSEKGIGKRTTIEEYRLTNRAGSGVIAMKLS-PKTGNIVGEVLV---------------------------------------
------------
>tr|A4ECR3|A4ECR3_9ACTN DNA gyrase C-terminal domain, beta-propeller OS=Collinsella aerofaciens ATCC 25986 GN=COLAER_02249 PE=4 SV=1
---------MVVTITHTGYVKRIPVAAYRAQKRGGKGVSGVNLKEDDVIDEMFIASTHEYVLFFSSKGKVYRLKVHELPVGTRQARGTAIVNLLPFEEGE
KIASVISCREFPANEYLMFATKSGMVKKTVMSAYDRSRRDGLIAINLRDDDALLNVRRVREGDKIILATTAGKAIMFSEEQVRATGRDTSGVRGIGMKDG
VSVLGMEVTNGNGDLFVITERGYGKRTPVADYPEQNRGGQGVYTIQMT-ERKGNLAAMKTVGPQHELFIVTEGATVIRVKTDEISQTGRATQGVKMMTVD
DNRICAVARMT-
>tr|F4N7W8|F4N7W8_YEREN Putative uncharacterized protein OS=Yersinia enterocolitica W22703 GN=YEW_JA39640 PE=4 SV=1
---LINQEDVVVTLSHQGYVKYQPLSDYEAQRRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEPNE
RITAILPVREYEEGRHIFMATASGTVKKTALTEFSRPRSAGIIAVNLNEGDELIGVDLTDGTNEVMLFSALGKVVRFPESQVRSMGRTATGVRGINLNGD
DRVISLIIPRGDGEILTVTENGYGKRTAVEEYPTKSRATQGVISIKVS-ERNGKVVGAVQVAPTDQIMMITDAGTLVRTRVSEVSVVGRNTQGVTLIRTT
EDHVVGLQRVA-
>tr|W1JKF4|W1JKF4_9BRAD DNA gyrase subunit A (Fragment) OS=Bradyrhizobium sp. CCGE-LA001 GN=BCCGELA001_36507 PE=4 SV=1
------------TVSHAGYVKRVPLSAYRAQRRGGKGRAGMQTRDEDFVSRLFVASTHTPVLFFSSRGQVYKEKVWRLPMAAPNARGKALINILPLEQGE
RITTIMPLPETWGELDVMFATTGGNVRRNKLSDFVDVRRSGIIAMKLDDGESIVDVQICTERDDVLLTAAGGQCIRFPVPDVRVTGRTSMGVRGIALGEG
DKVISLAILRHVQVVLTVSVNGYGKRTSSYEYRTTGRGGKGIVAMSVN-NRNGNLVASFPVEDADQIMLVTDKGQLIRCPVEGIRIAGRSTQGVIVFDTA
EDHVVSVEHIT-
>tr|A0A0P9AA29|A0A0P9AA29_9GAMM DNA gyrase subunit A (Fragment) OS=Psychromonas sp. PRT-SC03 GN=JI57_01055 PE=4 SV=1
---------VVVTLSHEGYVKYQPLTDYEAQRRGGKGKSATKMKDEDFIDKLLVASTHDTILCFSTRGRLYWLKVFQLPHASRQARGRPIINILPLEQGE
RITAILPVRKYDDDKFVFMATANGTVKKTALSAYSRPRASGLIAINLNDDNELIGALITDGSNDIMIFSDAGKVVRFKEAGVRPMGRTATGVRGIKLKEG
ERAVSLIVPNATGHILTCTENGYGKRTPLSDYASKSRATQGVISIKVS-ERNGKVVGAVQVDENDEIMLISNRGTLVRTPVHGVSIVGRNTQGVTLIKTR
DDKIVALQRIE-
>tr|A0A0Q1C5K8|A0A0Q1C5K8_NEIME DNA gyrase subunit A (Fragment) OS=Neisseria meningitidis GN=LD10_11755 PE=4 SV=1
---LIPQREMVVTLTHGGYIKTQPTTDYQAQRRGGRGKQAAATKDEDFIETLFVANTHDYLMCFTNLGKCHWIKVYKLPEGGRNSRGRPINNVIQLEEGE
KVSAILAVREFPEDQYVFFATAQGMVKKVQLSAFKNVRAQGIKAIALKEGDYLVGAAQTGGADDIMLFSNLGKAIRFNEYGVRPSGRGSGGLRGMRLPAD
GKIVSLITFAPELQVLTATANGYGKRTPIADYSRKNKGGQGNIAINTG-ERNGDLVAATLVGETDDLMLITSGGVLIRTKVEQIRETGRAAAGVKLINLD
EGTLVSLERVA-
>tr|R7KSY3|R7KSY3_9BURK DNA gyrase subunit A OS=Sutterella sp. CAG:521 GN=BN692_00644 PE=4 SV=1
---LIPRREMVVTMTRDGYIKSQQLSDYQAQRRGGQGKKAATMKEGDMIDQLFIANSHDRILCFSDFGRMYCLDVYALPEGSRTSKGRPIINSVPLSEGE
RITVVLPIEDFDDKHYVFMATANGVVKKTRLKDFANVRRSGINAAGLDDGDHLIGVAITDGEHDVMLFSDAGKAVRFSE-DVRPMGRGARGVKGMALEDG
QKVIAMIVADSEQTVLTATENGFGKRTLVSEYTRHGRGTKGMIAIQTS-DRNGKVVAATLVNDADEVMLLTQKGKIVRTPVSDISVLKRATQGVTLIGLK
DDLVA-VQRIA-
>tr|W7Q5M1|W7Q5M1_9GAMM Uncharacterized protein OS=Halomonas sp. BC04 GN=Q427_24745 PE=4 SV=1
---LIAEEDMVVTVSRTGYAKTQPLSDYQAQRRGGRGKSATSMKDEDVIEHLLVASTHDTVLLFSNKGKVYWLKVYEMPNASRGSRGKPLVNMLPLDEGE
AINAILPVRDYRADSYIFFATAKGTVKRTSLDQFSRPRSVGLIAIDLEEGDRLVGAAITSGSDHAMLLSSNGKAIRFEEGNVRSMGRTARGVRGMRLQGG
AEVISLIIPQSQIYILTASENGYGKRTRLEEFPLRGRGGQGVIAMQTS-ERNGSLVAAMQVYSADEMMLITDKGTLVRTRVDEVSITSRNTQGVMLIRLG
ENKLVKTVRID-
>tr|A0A009J8M0|A0A009J8M0_ACIBA DNA gyrase C-terminal domain, beta-propeller family protein OS=Acinetobacter baumannii 1396970 GN=J514_1424 PE=4 SV=1
---LIPEEQVVLTVSQTGYAKTQPLSDYQAQRRGGRGKSATSMKDDDFIQHLIVASNHATVLCFTNVGKVYRLKVFEVPQASRGAKGRPIVNLLPLDATE
TVTAILPLTEFPENHYVFMATASGTVKRVELEQFANIRSNGLRAIELNEEDTLIGVAITDGNQQIMLFSNEGKAIRFAETDVRAMGRTAKGVRGMRVSFA
SSTLSEEDAEVEGEVLCASANGYGKRTPVNDFPTKKRGGKGVIAIKTS-ERNGELVGAVSIDETKELLLISDGGTLVRTRAAEVAMTGRNAQGVRLIRLS
EETLVGVVSIE-
>tr|A0A0A3WAW6|A0A0A3WAW6_VIBPH DNA gyrase subunit A (Fragment) OS=Vibrio parahaemolyticus GN=HC02_13375 PE=4 SV=1
---LIAREDVVVTLSHEGYVKYQILSDYEAQRRGGKGKSATRMKDEDYIERLLVANTHDNILCFSTRGKTYRLKVYQLPLASRTARGKPIVNILPLEDGE
RITAILPVDEFSADKFIFMATGDGTVKKTSLDQFANVRSNGLIAVNLRDDDSLIGVDITTGSSDIMLFSKAGKVVRFSEDKVRAMGRTAAGVRGMKLADD
DQVVSLIVPSNEGDILTVTQNGYGKRTELAEYPTKGRATQGVVSIKVS-ERNGPVVGAVQVEEGDEMMMITDAGTLVRTRVAEVSQVGRNTQGVTLIRTA
EDSVVGLQRID-
>tr|W4RPE9|W4RPE9_9BACI DNA gyrase subunit A OS=Bacillus boroniphilus JCM 21738 GN=JCM21738_3203 PE=4 SV=1
---LIPRENIVITLTHNGYVKRLPVSTYRAQRRGGRGIQGMGTNEDDFVEHLITTSTHDTILFFTNKGKVYRSKGYEIPEFSRTAKGIPIINLLEIEKGE
WVNAIIPVEEFVDDWFLFFTTKEGISKRSPLSSFANIRNNGLIALNLREGDELISVRMTDGSKEMIIGTKNGLLIRFPETDVRSMGRTATGVKGISLSGD
DEVVGMEVLEE-AEILVVTKNGYGKRTPSEEYRRQGRGGKGIKTCNIT-DKNGDLVTMKVVTGEEDLMLITTGGVLIRIPVSSISMTGRNTQGVKLINLN
KANVATVAKVD-
>tr|A0A0P7FF36|A0A0P7FF36_9XANT DNA gyrase subunit A (Fragment) OS=Xanthomonas arboricola GN=AN651_16040 PE=4 SV=1
---LISPEDVVVTLSHAGYAKRQPVSAYRAQRRGGRGRSAAATKEEDFIDQLWLVNTHDTLLTFTSSGKVFWLPVYQLPEAGSNARGRPIINWIPLEPGE
RVQAVLPVREYADNRYVFFATRNGTVKKTPLSEFAFRLARGKIAINLDEGDALVGVALTDGDRDVLLFASNGKTVRFGESTVRSMGRTATGVRGIRLTKG
EEVVSLIVAERAAYILTATENGYGKRTPLTEYPRKGRGTQGVIGIQTT-ERNGKLVRAVLLGATDEVLLISDGGTLVRTRGSEISRVGRNTQGVTLIRLS
KGKLQAVERLD-
>tr|K8A7N3|K8A7N3_9ENTR DNA gyrase subunit A OS=Cronobacter muytjensii 530 GN=BN135_1144 PE=4 SV=1
---LINQEDVVVTLSHQGYVKYQPLTDYEAQRRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEANE
RITAILPVREYEEGVNVFMATASGTVKKTALTEFSRPRTAGIIAVNLNEGDELIGVDLTAGKDEVMLFSAQGKVVRFKEDAVRPMGRTATGVRGIRLGEG
DSVVSLIVPRGEGAILTATQNGYGKRTAVEEYPTKSRATKGVISIKVT-DRNGPVVGAVQVDDADQIMMITDAGTLVRTRVSEISVVGRNTQGVILIRTA
EDNVVGLQRVA-
>tr|D7H896|D7H896_VIBCL DNA gyrase, subunit A OS=Vibrio cholerae RC385 GN=VCRC385_01969 PE=4 SV=1
---LIAREDVVVTLSHEGYVKYQLLSDYEAQRRGGKGKSATKMKEEDYIERLLVANTHDNILLFSTRGKTYRMKVYQLPLASRTARGKPIVNLLPLEENE
RITAILPVTEFSEDKFIFMATGDGTVKKTSLDQFANVRANGLIALNLRDEDSLIGVDITDGESEIMLFSKFGKVVRFKESGVRPMGRTAAGVRGMKLADG
DQVVSLIVPKTEGDVLTVTENGYGKRTSLSEYPTKGRGTQGVVSIKVS-ERNGSVVGAVQVAEGDEFMMITNAGTLVRTRVAEVSQVGRNTQGVTLIRTS
EGSVVGLQRID-
>tr|G8C2J6|G8C2J6_9MOLU DNA gyrase subunit A OS=Candidatus Mycoplasma haemominutum 'Birmingham 1' GN=MHM_00260 PE=4 SV=1
---LERS-SKIISVSTKNYLAGIFLRKIRSTKRGRVGLDVGGYPKDVIANLTIAAENDDAILLFTNIGKVYKLSLDDEKAIVVGTWPEELVNISSFEKNE
RVVQLLPIKNFEEDKFFFMSTEKGMVKKLEISELSSITRAGKRVITLFEGDSLSHVIKIGAEDEVLLGLSTGYAVRFSSTSVRASGRASTGVKSIEIEPK
SGAIISL-SSTSALVVSIDEEGKGKCTSLREFRLTSRRSKGTIAYKLG-LSSNSLVTCAIVHDNEELVLLSDKNRINRIGVDQVTLRGRNTAGTILVRLE
QS-LFQFAKHA-
>tr|V9R9J1|V9R9J1_9MOLU Uncharacterized protein OS=Mycoplasma ovis str. Michigan GN=OVS_03780 PE=4 SV=1
---MQRE-SNLLFVNDDNWMSAIPLRVLEEQWWNKKQV-----SKGDQKLQMFMFKGDSQILIFTNLGRVYMMNGNDFTKNYSS--LQSNYCSSNVNSKE
RIVSVLSDHDDSDQFQLFLITEKGKCKKLETKHLRNVSKSGKIIIQLKDGDQLKQVQKIDSQSEIVLISSEGKAVRFSSSDVRSMGRNSMGVKGINLGSR
ELEEGKLSFLTTNRLLIIGDKGYGKIFKLPQISLVKRGNKKGMTCHNL-KTSGWIIFASCVNWDDHLIGLTYRNNLHKLQVDKLPVLNRYSRGAHILGEK
QRYLVEVIKYT-
>tr|W1VBP9|W1VBP9_9ACTO DNA topoisomerase (ATP-hydrolyzing) (Fragment) OS=Actinomyces urogenitalis DORA_12 GN=Q605_AUC00849G0001 PE=4 SV=1
MEDLIPEEEVVVTITRSGYAKRTRTDAYRSQHRGGKGVKGAALREDDVVDHFFVTTTHHWLLFFTNLGRVYRAKAYELPEGGRDAKGQHVANLLAFQPGE
EIAQVMELKDYEQADFLVLATKRGLVKKTRLSEYDSNRSGGVIAINLREDDELVSARLLSEGQDLLLVSRHGQSARFHASDLRPTGRATSGVTGMRFRDG
DWLLAMDVVDTDADLFVVTEGGYAKRTNVAEYPTKGRGGLGVKVANLVE-ERGDLVGALVTAPSDEVLCIMESGKVVRSRVDEVSVTGRNTQGVTFAKPD
DGRIIAVARNT-
>tr|A0A0E9E9G9|A0A0E9E9G9_CHLTH DNA topoisomerase (ATP-hydrolyzing) OS=Chlamydia trachomatis GN=gyrA_6 PE=4 SV=1
VEDLIAEENVVVTVTRAGYIKRTKADEYRAQHRGGKGIKGAKLREDDVVDHFFLTSTHNWLLFFTNRGRVYRIKAYELPEGSRDSKGQHVANLLQFTPGE
TIQAVLSIPNYDVAKYLVLATRSGKVKKTALQEYDSPRQGGLIAVRLMTNDELIGAALCNSEDDIILVSKLGMSLKFRADDLRPMGRQTAGVQGMRFREG
DELLDMDVVSTSKDLLVVTNEGFAKRTAIEEYRLQGRNGYGVKAVQLAE-GRGSLVGALIVEETDQVMAIMKSGKVIRSDVNEVKRTGRTTQGVTLAKPD
KGEIISIARNE-
>tr|A0A0J5TI71|A0A0J5TI71_KOCRH DNA topoisomerase (ATP-hydrolyzing) (Fragment) OS=Kocuria rhizophila GN=ACJ65_07630 PE=4 SV=1
MEDLIPQQQVVVTITRDGYVKRTRADEYRAQHRGGRGIKGAQLRGDDVVEHFFVTNTHHWILFFTTLGRVYRVKAYEFVEAGRDAKGQHVANLMEFQPEE
RIAKVMELRSYQDAPYLVLATRNGLVKKSRLTDYDTNRSAGVIAINLRDDDELVSAMLVDTDDDVMLISRHGQSLRFRADDLRPMGRATSGVTGMKFRSG
DELLSANVVH-DSHVFVVTEGGYAKRTSVQEYRVQGRGGLGIKVAKLAE-VRGGLVGGLIVGENDEVLVVMESGKVVRSTVSEVPARGRDTMGVIFAKPG
PETIVGVARNA-
>tr|D9X055|D9X055_STRVR DNA topoisomerase (ATP-hydrolyzing) (Fragment) OS=Streptomyces viridochromogenes DSM 40736 GN=SSQG_03931 PE=4 SV=1
IEDLIAEEDIVVTVTRGGYIKRTKTDDYRAQKRGGKGVRGTKLKEDDIVDHFFVSTTHHWLLFFTNKGRVYRVKGYELPDAGRDARGQHVANLLAFQPDE
AIAEILAIRDYEAVPYLVLATKAGLVKKTPLKDYDSPRSGGVIAINLRSMDELIGAELVSSDDDLLLISKKAQSIRFTASDLRPMGRATSGVKGMSFREG
DELLSMNVVR-GTFVFTATDGGYAKRTNVDEYRVQGRGGLGIKAAKIVE-DRGSLVGALVVEETDEILAITLSGGVIRTRVNEIRETGRDTMGVQLINLG
KRAVVGIARNA-
>tr|A0A0E9EY51|A0A0E9EY51_CHLTH DNA topoisomerase (ATP-hydrolyzing) OS=Chlamydia trachomatis GN=gyrA_7 PE=4 SV=1
MEDLIPEEDVVVTITREGFAKRTRTDNYRSQKRGGKGVRGTQLRGDDVVEHFFVTTTHHWLLFFTNLGRVYRAKAYEIPEGGRDAKGQHVANLLAFQPEE
HIAQVLAIRDYEVADYLVLATKSGLVKKTPLKLYESSRTGGIIGINLREDDELVSAQVINADQDLILVSRDGQAVRFVATDLRPMGRSTAGVRGMRFRGD
DELLSMEVPREGTDLLIVTDSGYAKRTPVEEYPTKSRGTMGVRVGKLVD-ERGGLVGALVVNPDEDVMVITESGKLVQVNASDVRPTARNTMGVIFARPD
EDRIIAITPNP-
>tr|C8XHV5|C8XHV5_NAKMY DNA gyrase subunit A OS=Nakamurella multipartita (strain ATCC 700099 / DSM 44233 / JCM 9543 / Y-104) GN=gyrA PE=3 SV=1
VEDLIAVEDVVVTITRTGYAKRTKTDLYRAQRRGGKGVQGAALKQDDIVAHFFVCSTHDWILFFTNKGRVYRAKAYELPEANRNARGQHVANLLAFQPDE
RIAEVIQIPHYQAAPYLVLATKGGLVKKSELAAFDSNRAGGIVAVNLRDDDELVGAVLCDANADLLLISAEGQSIRFHATDLRPMGRATSGVLGMRFNAG
DELLSMSVVYEGAQVLVATERGYAKRTDIDEYPVQGRGGKGVLTIQYDR-RRGKLVGALIVDLDTEVYAITSGAGVIRTQAREVRKAKRQTMGVRLMNLS
EGSLVAIARNA-
>tr|H9N0M1|H9N0M1_MYCTX DNA gyrase subunit A OS=Mycobacterium tuberculosis GN=gyrA PE=3 SV=1
DEDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLLAFQPEE
RIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELVGAVLCSADDDLLLVSANGQSIRFSATDLRPMGRATSGVQGMRFNID
DRLLSLNVVREGTYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDR-RRGRLVGALIVDDDSELYAVTSGGGVIRTAARQVRKAGRQTKGVRLMNLG
EGTPLAIARNA-
>tr|Q08NV9|Q08NV9_STIAD DNA topoisomerase (ATP-hydrolyzing) (Fragment) OS=Stigmatella aurantiaca (strain DW4/3-1) GN=STIAU_4480 PE=4 SV=1
EDAFIVDEDAHVVLTRDGWIKRVREVKDPS---------TTRLREGDAVMTVLAGSLKSNLVLFSNFGAAYVTRFNDVPAST--GYGDPVQKLFKFDDGE
RIVGALSLDSRLRPQKLVAVTKDGLGLRFPLEGHVEVSRSGRRYAKTGEGDEIIGVQPVGEKDLLAVLTERTYATVCRAAEVNELAGPGKGVLVIKVEPG
DRVMEFLAVAKDASITFETQKGRKLTLSPAKYEVTGRGGKGHEMSRKDT-VKE-VQ--RSVD--------------------------------------
------------
>tr|T0TFY8|T0TFY8_9STRE DNA topoisomerase (ATP-hydrolyzing) OS=Streptococcus sp. HSISB1 GN=HSISB1_984 PE=4 SV=1
VASLIVEEDTFVSVTKGGYIKRTSPRSFNASTVEEIGKR-----DDDELIFVSQAKTTQHLLIFTNLGNVIYRPVHELTDIRWKDIGEHLSQTITNATDE
CVLYAEIVDEFGPQTYFA-ATKLGQIKRFERKEISPWRSKAVKYAKLKNDDDMIVTISPIALDDVMVVTHNGYALHFNIDEVPVVGSKAAGVKSINLKDD
DFVVSTFIAN-TESFFILTQRGSLKRMSTDLIPATSRANRGLQVLRELK-SKPRVFMAGAVDKIETLEVYSNKGNIYNAILEDLTLSERTSNGSFISDKI
EGFSARIK----
>tr|Q2B016|Q2B016_9BACI DNA topoisomerase (ATP-hydrolyzing) (Fragment) OS=Bacillus sp. NRRL B-14911 GN=B14911_06843 PE=4 SV=1
LEVLIASEDVIVTVTNEGYVKRTSQRSFAASNGQDFGMK-----DSDRLMSKLDMNTTDVLLVFTDKGSYMYLPVHELPDIRWKDLGQHVANLVPI-RTE
SIIGAIPVKDFEAEAYLMFITKNGMVKKSELKNYKAQRSKPLVAVNLKNDDVVTDVFLTDGKQDLMLATSMGYALWFPEEEVSVVGARAAGVKGINLKDG
DYVVSGKLVSKEEAVVIATQRGAIKKMKLAEFERTSRAKRGLVMLRELK-ANPRVVG--MV---DKIFIESEKGVIEQVSASDLRFNDRYSNGSFILDES
GKKKMWQEAAD-
>tr|R5WTL8|R5WTL8_9FIRM DNA topoisomerase (ATP-hydrolyzing) OS=Blautia sp. CAG:257 GN=BN568_00850 PE=4 SV=1
MEDMIPRENTVITMTKLGYIKRMTVDNFRSQNRGGKGIKGMQTLDDDYIEELMMTTTHHYVMFFTNTGRVYRLKAYEIPEASRTARGTAIINLLQLMPGE
RITAVIPINKFEEDQYLMMATRKGLVKKTPIRDYANVRKIGLAAISLRDDDELIEVKVTNNKKDIILVTKDGQCIRFKETDVRTTGRVSMGVRGINLMDG
DEVVGMQLN-QGYYLLVVSENGMGKRTSISEFTCQNRGGKGVKCYKITE-KTGNVIGAKAVNEENEIMMITTEGIIIRLQCSDISILGRITSGVKLINLS
DGTVASFAKVR-
>tr|R5HXC5|R5HXC5_9FIRM DNA topoisomerase (ATP-hydrolyzing) OS=Ruminococcus sp. CAG:60 GN=BN729_00768 PE=4 SV=1
TEDLIPRENTVITMTKLGYIKRMTVDNFRSQNRGGRGIKGMQTIEDDYIEELLMTTTHHYLMFFTNTGRVYRLKAYEIPEAGRTARGTAIVNLLQLMPGE
RITAVIPMRNFEEGRYLVMATKNGLVKKTPMEEYANVRKTGLVAITLRDDDELIEVKATDNNKDIMLVTKDGMCIRFKETDVRSTGRSSMGVRGMNLDPG
DEVVAMQLN-QGDYLLVVSENGMGKRTAMSEFTCQNRGGKGVKCYKITE-KTGNVIGAKAVNEENEIMMITTEGIIIRITCAGISILGRITSGVKLINLD
EGTVASLAKVR-
>tr|R6N9S7|R6N9S7_9FIRM DNA topoisomerase (ATP-hydrolyzing) OS=Lachnospiraceae bacterium CAG:364 GN=BN627_00100 PE=4 SV=1
MEDLIPKENTVIAMTKLGYIKRMTVDNFRSQNRGGKGIKGMSTIDDDYIEELLMTTTHHYLMFFTSAGRVYRIKAYEIPEASRTARGTAIINLLQLQPEE
KITAVIPINEFKKGNYLFMATKNGLVKKTPIEDYENVRKTGLAAIALREDDELIEVKFTDNKKDIILVTKFGQCIRFNETDVRSTGRVSMGVRGINLLEE
DEVIGMQLT-QGDYLLIVSEKGLGKRTSISEFTRQNRGGKGVKCYKITE-KTGNVIGVKAVNSENEIMMITTEGIIIRLECEGISILGRITSGVKLMDLK
DDTVASIAKVR-
>tr|A0A0J1G052|A0A0J1G052_9FIRM DNA topoisomerase (ATP-hydrolyzing) OS=Robinsoniella sp. RHS GN=RHS_5198 PE=4 SV=1
MEDLIPRTNVVIAMTKLGYIKRMTIDNFKSQNRGGKGIKGMQTIDDDYIEDLLMTSTHHYLMFFTNTGKVYRLKAYEIPESSRTARGTAIINLLQLAPGE
KITAMIPIKEYKAGRYLFMATKNGIVKKTPIRDYANVRKTGLAAISLREEDELIEVKTTNNEKDIILVTKYGQCIRFHETDVRSTGRTSMGVIGMSLSHG
DEVIGMQLN-QGEYLMIVSEKGMGKLTHMNEFTAQNRGGKGVKCYKIME-KTGNVIGVKAVNKENEIMIISTEGIVIRMMCGDISVLGRVTSGVKLINMD
NDMVASIAKVR-
>tr|R6TAR5|R6TAR5_9FIRM DNA topoisomerase (ATP-hydrolyzing) OS=Eubacterium rectale CAG:36 GN=BN626_02352 PE=4 SV=1
MEDLIPETNTVITMTKVGYIKRMSTDNFKAQHRGGKGIKGMETIEDDYIVEMLMTTSHHYLMFFTNTGRVYRIKAYEIPEASRTSRGTAIINLIPLQPDE
KITAMIPIKEYEDDKYLFMATRNGIVKKTPIKDYENIRKNGLAAINLREDDKLIEVKVTDNSEDILLFTKFGQCIRFKETDVRSTGRTTMGVIGMNLAPN
DVIIAMQTA-MGEAVLLVSSNGLGKRTRIDEFTTQNRGGKGVKCYKITE-KSGNLVGVKSVENDDELMLITTEGIIIRIQVSDVTVLGRITTGVKLINLK
EGSVASIAKVV-
>tr|R5IGE1|R5IGE1_9CLOT DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium sp. CAG:7 GN=BN757_01560 PE=4 SV=1
MEDLIPDEDTVIAMTHLGYIKRMDVDNFRSQNRGGKGIKGMQTIEEDYIEDLLMTTNHHYMMFFTNTGRVYRIKAYEIPEAGRTARGTAIVNLLQMQPGE
KITAIIPMRELNEDKYLFMATKKGMVKKTPMLEYENVRKNGLQAIVLRDDDELIEVKATDNTQDIFLVTKKGMCIRFKETDVRVTGRVSMGVIGMRFDED
DEVIGMQME-QGEHLLVVSENGMGKRTLISEFNAQIRGGKGVLCYKVTE-KTGYLIGAKLVNDGREIMLITTEGIVIRMSVDDISVIGRNTSGVKLMNID
SDKVASIAKVR-
>tr|R6EB29|R6EB29_9BACE DNA topoisomerase (ATP-hydrolyzing) OS=Bacteroides sp. CAG:709 GN=BN760_01812 PE=4 SV=1
PEDFYADDDEVITISHFGYIKRTPLAEYKTQNRGGVGMKGTATRDEDFIEHLYVANMHSTMLFFTEQGKCFWLKVYEVPEGSRSSKGRAIQNVLSIPDD-
KIKAIINVPEYINSHFIILATKEGIIKKTSLEAYSRPRAKGVNAVNVREGDELLEAILTDGKSEVLIASRNGRCVRFDETDARPLGRTATGVRGINLDED
DYVIGMVCYEAAHTLLVIGEKGLGKRTDFEEYRKTSRGSKGVRTMNITD-KTGKLVALKNVTEENDLLIITQSGLIIRMAVADIKQAGRNTQGVKLINIR
-D-IASVSVVA-
>tr|R5L4A1|R5L4A1_9CLOT DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium sp. CAG:921 GN=BN811_00251 PE=4 SV=1
IESLIKEETNVVTLTHFGYVKRIAADVYRSQKRGGKGLTAMNTREDDFVEQLFITSTHDYIMFFTNKGKVYRLKAYELPEASRTAKGTAIVNLLQLDQGE
KVAAIMPVKDYSAELYVLMATRNGLIKKTKLEEYSNIRKSGLQGITLKEDDELIDVRLTDGSNDVVMVTQSGLSIRFKEEEVRPVGRTSMGVKGITLAND
DKVVGMEPVANDDYILTITENGFGKRTELEEYRSQCRAGKGVLTYKTTA-KTGHIIGIKIVNDFDDIMMITDTGVIIRINVKDISVLGRNTQGVTLMRTS
DGKVINIAKIP-
>tr|R6AIX8|R6AIX8_9FIRM DNA topoisomerase (ATP-hydrolyzing) OS=Eubacterium eligens CAG:72 GN=BN765_00174 PE=4 SV=1
MEDLIPDEPCVIARTNLGYVKRMTPDNFKSQHRGGKGIKGMQTIDDDYIKDLFMTTSHHVLTFFTNTGRAYKLKAYEIPEASRTSRGTAIINLLQLAPGE
TITAVVPVKTLQDTDYLFMATKKGIVKKTPVKDFANIRKTGIQAINLREDDELIEVKLTDDQAEILMVTMLGQCIRFKETDVRPTGRSAMGVIGMSLMDE
DEVVGVQVS-QGDTMLIVSENGMGKRTDIDEYTVQHRGGKGVKCYKITE-KTGNVVGAKAVDDSREVMLITTEGIIIRLQCSDISNLGRITSGVKLINLD
EGKVATIAKVR-
>tr|A0A0E9EU34|A0A0E9EU34_CHLTH DNA topoisomerase (ATP-hydrolyzing) OS=Chlamydia trachomatis GN=gyrA_6 PE=4 SV=1
DEDLIEEEEVVITLTNNGYIKRMANSEFRAQRRGGRGVQGMGVHDDDFVKNLVSCSTHDTLLFFTNTGKVYRAKGYEIPEYGRTAKGIPVINLLGIDSAE
KIQAIISVEKAEAGKYLFFTTLKGTVKRTAVTAFSNIRSNGLIAISLKEDDELVNVVTTNGNQKMIIGTHAGYSVTFDENTVRDMGRTASGVRGIRLREN
DYVVGAAIL-ENKEVLVITENGYGKRTKASEYPVKGRGGKGIKTANITE-KNGPLAGLTTVNGDEDILLITNKGVIIRFNVDSVSQTGRATLGVRLMRME
DGKVVTMAVVE-
>tr|R7NZB7|R7NZB7_9BACE DNA topoisomerase (ATP-hydrolyzing) OS=Bacteroides vulgatus CAG:6 GN=BN728_02377 PE=4 SV=1
PEDFYADDQMVITISHMGYIKRTPLSEFRAQNRGGVGSKGSETRDEDFVEHIYPATMHNTMMFFTQKGKCYWLKVYEIPEGTKNAKGRAIQNLLNIDSDD
VVTAYLRVKEFINSHYVLFCTKNGVIKKTLLEQYSRPRQNGVNAITIREDDKVIEVRMTNGDNEIIIANRNGRAIRFHESAVRVMGRTATGVRGMTLDED
DEVIGMICIKEAESIMVVSEQGYGKRSDIEDYRKTNRGGKGVKTLNITD-KTGKLVAIKSVTDENDLMIINKSGITIRLKVAEVRIMGRATQGVRLINLE
-NQIGSVCKVT-
>tr|A0A0E9FTY8|A0A0E9FTY8_CHLTH DNA topoisomerase (ATP-hydrolyzing) OS=Chlamydia trachomatis GN=gyrA_3 PE=4 SV=1
DEDLIPKEDVIVMLTMSGYIKRMPVDTYHAQNRGGRGIKSLTLNEEDDIDTMISLNTHDHLMLFTDLGRVYRLKGYNVPSGSRTSKGLPIVNLIQLEENE
HVTALLGIPQDHSYENLLFVTKDGVVKRTQLSEFDRINRNGKIAISLKEDDVLLFVKPTSGHDQVMLACSNGKVARFDEKDIRQMGRSASGVRGMNTDGG
-SIVGAAMD-EGDTLLSISENGYGKRSKVEDYRLTSRGSKGVATMNVTE-KTGALKLVKAVRGDEDAMIVSSSGIMIRISVADIGIYSRNTQGVRLINLT
DDKVMRLTLVD-
>tr|U5P0S8|U5P0S8_9CLOT DNA topoisomerase (ATP-hydrolyzing) OS=Youngiibacter fragilis 232.1 PE=4 SV=1
YEDLISEEDVVITLTQSGYIKRIQAATYSSQKRGGRGIQAMSTKEDDIVSKVFVTSTHKNLLFFTSKGKVYKLKAYEIPDAGRVSKGTNLVNIIPLDQDE
KIQAVISIADMDQDGFLVFCTANGIVKKTGLEDYSNIRKNGLIAINLREGDELLNVKFTRGDADLILVTQDGYSIKFNENEIRTMGRTASGVKGIDLRSG
DTCVSFDIA-EGEDLLVVSESGLGKRTPISEYHLQRRGGKGLITYKVSS-RTGPVVGARSCSQDDELMLINSDGVAIRISIAEISETSRNTMGVKLMKTS
ETKVVSMAKII-
>tr|X0Z1F4|X0Z1F4_9ZZZZ Uncharacterized protein (Fragment) OS=marine sediment metagenome GN=S01H4_04279 PE=4 SV=1
IEDLIPEEENVISISHSGYIKRLPVATYRKQGRGGRGVTGTNLKEDDFVKHLFIASTHHYIMFFSNLGKVYRLKVYQIPTGSRVSKGRAIVNLLPFVPGE
RVAAIIAVRDYGADQYLIMATKKGIIKKTSIKVYDTSRRDGIIAITIKKGDELIGVEKSNGNNDIIMVSRNGKAIRFSEKDCRPIGRTSQGVKGMRLSRG
DEVLSMMVAGLEGDLFVLTENGYGKRTQLSEYKKQKRGGLGVRTLKITE-KKGKV---------------------------------------------
------------
>tr|R5K9Z2|R5K9Z2_9CLOT DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium sp. CAG:632 GN=BN743_01127 PE=4 SV=1
DEELIKRENTVIAMTKLGYIKRMTVDNFRAQNRGGKGIKGMQTIEDDFIEELIMTTTHHFIMFFTNLGRVYRLKAYEIPESGRTARGTAIVNLLQMLPGE
HITAVIPIREFKPGRYLLMATKKGMIKKTPITDYQNIRKNGLAAITLRDEDELIEVKSTNNKKEVILVSKQGMCIRFLETDVRSTGRTSIGVKGMNLNAG
DEVIGMQLD-QGEDLLIVSENGMGKRTSMDEFTPQNRGGKGVKCYKIND-KTGNVIGVKAVNEDNEIMLISTEGIVIRLQCSDISRLSRVTSGVKLINMD
NNHVASVAKVR-
>tr|G4KKR7|G4KKR7_9CAUD DNA-gyrase A-subunit OS=Yersinia phage phiR1-37 GN=g329 PE=4 SV=1
VKAFVQPENLVIGFDNAGYVFAKSTDEISGDTRGRKGQNFVPSTVKKVIIETFTVNTHDYILCFTTDGKLIIRQGYEFNMW-----NKPIGAILNL-EGR
RISTIIPITEKDLDKYLVFVTEAGYMKRIPVDGFDLNRKAAVIAIKPTEGDILKAVSSLSEIDNVFVYSNEGKAQRLLASQIDEMTRASAGRCRLTLGED
EYVVGLTVGNDTTKILMCASNGKGKIIDLEEFPLR-RGDKGRRSMAITL-AEGMLIGALIVKEEDSVAFNTSNNKIVSLNVANVTTLGRNAKGMTLAKPS
EGIITSITYSN-
>tr|M5RM44|M5RM44_9PLAN DNA topoisomerase (ATP-hydrolyzing) OS=Rhodopirellula maiorica SM1 GN=RMSM_02670 PE=4 SV=1
LEDLITEETMVVSISHRGYIKRTPTSVYNTQRRGGKGLKGAKTDDEDPIEHLFVASTHAYLLFLTTLGKVRWQKVYDLPQLARDSKGRAIVNLLNLSEDE
KIAECLAIRDFDAGYYVVMATRSGLVKKTPLEQYSRPKKGGIIAIKLREGDELVGAAVIGPGDEVILVTSSGMAIRFRESDARPMGRNTSGVKGIKLVGD
DSVVGMVVAD-EATLLTVCENGYGKRTHFARYRTQKRGGKGLRDIRTSE-RNGPVIGIARVTDEDELFMMTAKGKLQRIKAADINVIGRNTQGVRIMNID
SGSLIAVVRVP-
>tr|A8V0U3|A8V0U3_9AQUI DNA topoisomerase (ATP-hydrolyzing) (Fragment) OS=Hydrogenivirga sp. 128-5-R1-1 GN=HG1285_08131 PE=4 SV=1
-----FEENYIIAVLSNGKIINYKIDNPEDREEKERIFNTSLILPGDYLVSIQEIKSSQPIAFITNDGRCIWSLAADLPKGEGKLKYI---------DEN
KIVGTA-F-KSEEEDRLFLLTKNGIIKRMTFEDIFYKSQ-NQQIIPLQEDDEIVMAFADDHPSYIAIYTAKADLLIFERNQIRVTGAKAKGVEGIDLDEG
DYVKGGFLVNSEEYILTITKNGQCKLVNKEEFPIKKRAQKGLMAVKLQK-G-DELNICTSVNIEDEVILSTSGGKVFKMIIDDIPVAKRTAMGDKLLNEE
---IIWLAKPK-
>tr|I6YQJ5|I6YQJ5_STRIN DNA topoisomerase 4 subunit A OS=Streptococcus iniae GN=parC PE=3 SV=1
TASLIVEEETFVSVTKGGYIKRTSPRSYNASTHDEIGKR-----DDDHLIFVSQAKTTQHLLLYTDLGNVIYRPVHELVDIRWKEIGEHLSQNISNATDE
AVIYAELVDQFDKGSYIS-VTKYGQIKRFDRSDISPWRSKSMKYAKLKNDQDKVIGLQPVFFEDIMLVSHNGYALRFSSEEVPQQGLKTSGVKAMNLKKD
DFIVSAFLVT-EPSFFILTQRGSLKRVSATEIPATSRANRGLQVLRELK-NKPRVFLAGNVADSQLLEVMSKTGESKEINLAQLNLSERTSNGSFISETI
QELAARIH----
>tr|B9DSB4|B9DSB4_STRU0 DNA topoisomerase 4 subunit A OS=Streptococcus uberis (strain ATCC BAA-854 / 0140J) GN=parC PE=3 SV=1
TASLIVEEETFVSVTKSGYIKRTSPRSFNASSLEEIGKR-----DDDHLIFVENAKTTQHLLLFTDQGNVIYRPIHELQDIKWKEIGEHLSQHITNATDE
LILHAEIVDYFEKGSYFS-VTQLGQIKRFDRKDLTPWRTKSTKYAKLKNEQDRIVSVAPIFFEDILLISHQGYALRFSAEEVPVQGLKSAGVKAMNLKAG
DHIAAAFLAS-TDSFFVLTQRGSLKRVATSDIPQTSRANRGLLVLRELK-NKPRVFFAGAVNQAQELLVISKTGQEYVIDLRSYSLAERTSNGSFISDTI
QELTATIK----
>tr|A0A0D1AGT8|A0A0D1AGT8_STRSZ DNA topoisomerase 4 subunit A OS=Streptococcus equi subsp. zooepidemicus Sz16 GN=parC PE=3 SV=1
SASLILEEETFVSVTQGGYIKRTSPRSFHASSLEEIGKR-----DDDHLIFVKQAKTTDHLLLFTNLGNVIYRPVYELTDLRWKDIGEHLSQAITNAADE
MVIYAELIQSFEQGLYAS-VTQHGLIKRFERKEMMPWRSKSIKYAKLKAADDRIIAIAPIVMEDLLLVTQQGYALRFSSQEIPIQGLKAAGVKGINLKAQ
DYLVSACPVN-ADSFFVLTQRGALKRVAIADIPQTSRANRGLLVLRELK-TKPRVFLAGMVASDQQLEVISKTGQQYQLALNSLSLSDRTSNGSFISESI
QEAAARLI----
>tr|A0A0B5FMU8|A0A0B5FMU8_9DELT DNA gyrase subunit A OS=Geoalkalibacter subterraneus GN=gyrA PE=3 SV=1
LEDLIVEEDMVVTVSHSGYIKRNAVSLYRAQRRGGKGKTGMRP-DEDFVERLFIASTHSNVLFFTDQGKVYWLKVHEIPQGGRASRGKAIVNLLNLAP-E
KVMTVLPVK----GKYILTATQNGIVKKTDLMAYSN-RAGGIIALTIDEGDRLIAAR-TDG-MDILLASRNGKSIRFHE--VRSMGRTARGVRGMALE--
DLVIGMETVTEAATLVTVTENGYGKRTSLDEYRVQSRGGKGIITIKAS-E-NGKVVDIKLCED-SDLMFITDRGKVLRTSVGHLSIIGRNTQGVRLMVLE
-DRIVAVAKLA-
>tr|U7NJF0|U7NJF0_9GAMM DNA gyrase subunit A OS=Halomonas sp. PBN3 GN=gyrA PE=3 SV=1
IEDLIAEEDMVVTVSRSGYAKTQPLSDYQAQRRGGRGSATA-MKDEDVIEHLLVASTHDTVLLFSNRGKVYWLKVYEMPAASRGSRGKPLVNLLP-LDGE
AINAILPVRDYDPESYIFFATARGTVKRTSLEQFSRPRSVGLIAIDLEEGDRLIGAQITSGSDHVMLLSSNGKAIRFEEGSVRAMGRTARGVRGMRLLDA
E-VISLIIPQSQIYILTASENGYGKRTRLEEFPLRGRGGQGVIAMQTSE-RNGALVAAMQVYASDEMMLITDRGTLVRTRVDEVSISSRNTQGVMLIRLG
NDTLVKTVRID-
>tr|S7UU06|S7UU06_DESML DNA gyrase subunit A OS=Desulfococcus multivorans DSM 2059 GN=gyrA PE=3 SV=1
MEDMIAEEDMVVTISKAGYIKRNPITLYQSQRRGGKGKTAMGT-EEDFVEHLFVASTHHTFLFFTNQGKVYWCKVYEIPQAGRASKGRAIVNLLNFEA-E
KLTTVLAVP----GSYIMMATRQAVIKKTDIMAFSR-RAGGIIALALAPGDELIGTR-TDG-NNVFLGSASGKSIRFHE--IRPTGRTARGVRGMTLA--
DILVGMEVLSHGQTLFTATENGYGKRTLIDEYPIQRRGGKGVITIKTS-K-NGQVIAILLVAE-DELMLMTDSGKLIRMPVSGISVISRNTQGVKLMDLD
-ERVIGAARLA-
>tr|E1YB56|E1YB56_9DELT DNA gyrase subunit A OS=uncultured Desulfobacterium sp. GN=gyrA PE=3 SV=1
IEDLIVEEDMVVTVSKDGYIKRTPASIYNSQSRGGKGKTAMMT-EEDFVSMLFVASTHHYFLFFTNQGKVYWCKVYDIPEAGRTSKGKAIVNLLNFAE-E
KLTTVLAVKG----SFVIMATRSGQIKRTDIMAYSR-RAGGIKALKLDEGDELIAVR-TDG-LNVFVCSAMGKSIRFHE--IRATGRVTGGIRGMRLA--
DRIVGMEVLT-GQTLFAVTENGFGKRTSIDEYPVHKRGGKGVICIKTS-E-NGQVVAILIVDD-DDLMLMADSGKIIRTPISGISVISRNTQGVKLINRE
-TKVIGAARLA-
>tr|A0A0F2R090|A0A0F2R090_9DELT DNA gyrase subunit A OS=Desulfatitalea sp. BRH_c12 GN=gyrA PE=3 SV=1
IEDMIVEEDMVVTISNSGYIKRNPITLYQSQRRGGRGVTGMGM-DEDFVSHLFVASTHHSFLFFTNRGKVYWCKVYDIPQAGRTGRGKAIVNLLNFEE-E
HMTTVLAVP----GHYVLMATKAGTVKKTDIMAFSR-RVGGIIALGLSEGDELIAAR-TDG-QNVFLGSAMGKSIRFHE--IRPSGRLSHGVRGMRLD--
DRLIGMEVVRFGQTLFAVTINGYGKRTSIDEYPVHGRGGKGVITIKTN-E-NGEVVGLLAVQD-HDIMLVTDRGKIIRIPVSNISVISRNTQGVRLIGME
-GRVVSAASLA-
>tr|D4H6E8|D4H6E8_DENA2 DNA gyrase subunit A OS=Denitrovibrio acetiphilus (strain DSM 12809 / N2460) GN=gyrA PE=3 SV=1
DEDLIPNNEKVVTMTHNGYIKATLLSSYVAQKRGGKGKTGAGS-DEDFVERLIVTTNHTRLMFFTNTGKVHYLKVYALPEAQRDAKGRHISNLL-TEPEE
FVASVLALP---DGKYLFFATKSGTIKKTSLEEFKSG-RSGIVAIKLRDGDEILTAD-TTDEDTVILSTKAGKTIQFSS--ARPMGRSTSGVRGITLE--
-DLMSMEVLTG-PYILSVTSAGYGKRTPVDEYRVQTRGGKGLKLC--SK--TGFVVGAKQVTDNDDVMIITRSAKTIRTEVQGISKMGRDTMGVKLMDTG
-DIIA-FAVIK-
>tr|A0A0M9E3M3|A0A0M9E3M3_9DELT DNA gyrase subunit A OS=Candidatus Magnetomorum sp. HK-1 GN=gyrA PE=3 SV=1
LEDMIVEEDMVVTVSNAGYIKRTPLSVYHSQRRGGKGKTAMET-DKDFLAHVFVASTHHYFLFFTNMGQVYWCKVYDIPQSGRVSKGKAIVNLLDFAE-E
ELATVLPVAG----SFVIMATKNGLVKKTDIIAYSR-RTNGIRAISLVPGDELISAR-TDG-HNIFLASCLGKSIRFHE--IRPSGRTARGVKGIKLA--
DRIVGMEVLS-GETLFVVTENGFGKRTSINEYTLQARGGKGVITIKTS-A-NGLVVSILLVED-DDVILMTETGKIIRLQVENISKISRNTQGVKLMDLD
-GRITAAVRLS-
>tr|A0A0K9IBE3|A0A0K9IBE3_9DELT DNA gyrase subunit A OS=Desulfocarbo indianensis GN=gyrA PE=3 SV=1
LEDMIAEEEMVVTISHAGYIKRSPISLYRSQRRGGKGVRGMVP-DEDFVESLFVASTHSYMLVFTTKGRLYWIKVHELPQGGRATRGKAIVNLLNVEP-D
HVATVLAVRG----RQVVMATQNGTIKKTDLMAFSR-RAGGIIAINIGDDDKLVSAR-TDG-MEIFLATKKGQAIRFRE--VRSMGRTAAGVKGIDLA--
DGLVAMEAVA-APALLTVTENGYGKRTQIDEYPLQRRGGKGVITIKTT-E-NGPVVGALLVGD-DEVMLISDQGKIIRMKIGDLRVIGRNTQGVKLIGLD
-DRLVSVARLA-
>tr|A3ZRK0|A3ZRK0_9PLAN DNA gyrase subunit A OS=Blastopirellula marina DSM 3645 GN=gyrA PE=3 SV=1
LEDLIEEETMVVSISHSGYIKRTPATTYKAQRRGG-G--KAK--AD-PIQHLFVASTHAYLLFFTTKGKVYWQKVYDLPQS-RESRGRAIVNLL-QEG-E
R--DCRAVR--VEDHYLVMATRKGLVKKTKLEAYSR-M-KGIIAIKLR--DELVD---T---DELVLSTSKGMAI------ARPMGRNSSGVKGIKLD--
DDLVGMVVAD-DAQLLTVCEHGHGKRTYF-KYR-QRRGGKGLRDI---TARNGRV-SIVRVD-EDEVLMMTARGKIQRVSA-EISI-GR---GVRIMSLD
D-SLAAVVRVP-
>tr|I0IBH7|I0IBH7_PHYMF DNA topoisomerase (ATP-hydrolyzing) OS=Phycisphaera mikurensis (strain NBRC 102666 / KCTC 22515 / FYK2301M01) GN=gyrA PE=4 SV=1
-GDMIAEHQAVVTITHRGYVKRIAAEEFRQQARGGRGVAGAA--QD-FTTEVLVASSHDDLLCFTDTGRVFKKKVYEIPET-RTSKGRAIVNVM-NGE-E
R--EFMPIAG---EDFLLFSTANGLVKRTALADYRN-HSGGLIAVGLR-D-KLIG---G--DDHVILGTASGMAI------ARAMGRNAAGVKGIAL-G-
-SVVGVVRCD-ASDLLSVTENGYGKRTPT-EYLRQGRGGKGRRDI--TR--NGRV-IKR-VE-GDGLVCITSGGMIVRIAS-DVRQ-HR---GVRVINVK
G-LAA-VSPIK-
>tr|A0A0D3BAL8|A0A0D3BAL8_BRAOL Uncharacterized protein OS=Brassica oleracea var. oleracea PE=3 SV=1
DIDVIPNEEMLMAISEKGYVKRMKPDTFNLQNRGT-G--S-GK-DD-AMSDFLVCHAHDHVLFFSDRGIVYSTRAYKIPES-RNAAGTPLVQIL-SSG-E
R--SIVPVS--SEDQYLLMLTVNGCIKKVPLKLFSG-R-TGIIAIQLN--DELKW---S---DLVAMASQNGMVV------VRTLSRNTKGVTAMRLKN-
-AMASMDIIPSGPWLLFVCENGYGKRVPL-SFK-SRLNRVGLIGS---AED--DL-AVFVVGDDEQVVLVSQTGTVNRIKV-DISI-SR---GVILMRLD
A-KIQSASLIS-
>tr|A0A0E3RVS5|A0A0E3RVS5_METMZ DNA gyrase subunit A OS=Methanosarcina mazei C16 GN=gyrA PE=3 SV=1
DEDLIPEEDVVVTITNSGYIKRIPLDTYTMQRRGGRGIIGMEM-EEDFVENLFISSTHNYILFFTNRGRLYWQKVYEIPEGSRQSRGKAIVNLLELQE-E
MVNAMISVE----DKYLFMATRAGTVKKTPLSEFRN-RRAGIIAVSLDEGDELVKVL-TDG-QEIMMVSKKGKAIRFSE--VRPMGRTARGVRGMTLEP-
-DVVSLDLVDETTTLLTVTDNGFGKRTEYSQYPVHRRGGKGVITIVTN-L-NGFVSNVKSVAD-DELMFTSAEGIIIRIPAKDISIQGRNTQGVRVMNIK
G-KVGGMARIK-
>tr|A0A0A2WWA5|A0A0A2WWA5_THEFI DNA gyrase subunit A OS=Thermus filiformis GN=gyrA PE=3 SV=1
KEDLIEDEPMVITLTAQGFLKRTPLESYRAQGRGGMGAQAGRA-EEDEAVRVFVAQMHDDLLVFTNRGWVYRVKVYDLPELGRQARGVHVRALL-PAEDE
EVAALRSVR---KEGYLVFATERGLVKRTALSEYKNLGSAGLIAIKLLEEDRLVDVD-AEEDGEVVLATREGQAIRFPL--VRATGRDSQGVTGIRFK--
-GRVVSLVVLSDPDLLAVSTKGFGKRTPLSEYPLQGRGGMGVITY--SR--VGSLAALLKVGAGADLLVLSKRGLAIRTPVKEIPRYSRATAGVRVMNLA
-GEVASAFVVK-
>tr|K7QVY1|K7QVY1_THEOS DNA gyrase subunit A OS=Thermus oshimai JL-2 GN=gyrA PE=3 SV=1
PEDLIEDEPVVITLTAQGFLKRIPLEAYRAQGRGGRGAQAGKT-EEDEATHVLVAATHDDLLFFTGRGRVYRLKVYELPEMGRQARGVHVKSLL-PSEEE
EVAALLSVR---GEGDLLFATEGGMVKRTPLKEYRNLGSAGLIAIRLHPEDRLIGVA-ADPEDEVILATREGMAIRFPL--VRATGRDTQGVTGIRFK--
-DVVSLVAVKPMAELLAVSTRGYGKRTPLAEYPLQGRGGVGVITY--SK--VGTLAALLKVKGTEDLLVLSKRGLALRTPVAEIRTYSRATAGVRIMNLP
-DEIASAFVVE-
>tr|A0A0N0ZND1|A0A0N0ZND1_THESC DNA gyrase subunit A OS=Thermus scotoductus GN=gyrA PE=3 SV=1
PEDLIEDEPMVITLTAQGFLKRLPLESYRAQGRGGKGLIAGKT-EEDEAIQVFVAQAHEDLLLFTNRGRVYRLKVYELPEMGRQARGVHVKTLL-PAEEE
EVAALLSVR---GEGYLVFATERGLVKRTALREYQNLGAAGLIAIRLLEGDRLIGVA-SDPEDEAILATEEGQAIRFAL--VRATGRDSQGVTGIRFK--
-DVVSLVTVKPMVDLLAVSTRGYGKRTPLAEYPLQGRGGMGVITY--SK--VGRLAALLKVRGTEDLLVLSKKGLAIRTPVADIRQYSRDTAGVKVMNLP
-DEVVSAFAVE-
>tr|A0A0N0BLT6|A0A0N0BLT6_THEAQ DNA gyrase subunit A OS=Thermus aquaticus GN=gyrA PE=3 SV=1
PEDLIEDEPMVITLTAQGFLKRLPLEAYRAQGRGGKGLMAGKT-EEDEATHVFVADAHDDLLVFSNRGRVYRLKVYDLPEMGRQARGVHVKTLL-PAEEE
EVAALLAVR---GEGYLVFATERGLVKRTALKEYANLGAGGLIAIRLLEGDRLVGVA-SDPEDEAILATAEGQAIRFPL--VRATGRDTQGVVGIRFK--
-DVVSLVTVKPMVDLLSVSTRGYGKRTPLSEYPPQGRGGMGVITY--SR--VGRLAALLKVRGTEDLLVLSKKGLTLRTPVAEIRQYSRATAGVKVMNLP
-EEIASAFVVE-
>tr|R2PVT4|R2PVT4_9ENTE DNA topoisomerase 4 subunit A OS=Enterococcus pallens ATCC BAA-351 GN=parC PE=3 SV=1
TEVLIAQEDVVVTVTQEGYMKRSSLRSYNASR--P---------GD-RVLFA-QKNTLDHVLILTNRGNMIYRPVHEVAD-----VGEHISQTISS-KDE
E--AVFPYK----NQLFVLMTKEGMIKQTRMTEFS----RPTAAIKLK-TDRVVA---K--NLDVFVGTYRGFGL------V--VGAKAAGVKAVNLKG-
-YVVGGALVLSDSPITLISQRGAAKRMLAQ------RAKRGLMIF----RLAHRV-YLTDTI---EIELLSQKGTTQTLEI-KIPV---LANGSFAIDEK
D--VFAVYETK-
>tr|R2RHV6|R2RHV6_9ENTE DNA topoisomerase 4 subunit A OS=Enterococcus raffinosus ATCC 49464 GN=parC PE=3 SV=1
TEVLIAQEEVIVTLTKEGYLKRSSLRSYNASR--P---------GD-SIIFI-DKNTLDHLLILTNHGNMIYRPVHEITE-----VGEHISQTITN-STE
E--AAFPYK----NKLFIFMSKEGMIKQTRMTEFS----RPTTAMKMK-TDQIVS---D--NVDVFIASHRAFGL------V--VGSKAAGVKAINLKG-
-YVVSGALVPSDSPILLLSQRGAAKRMLAQ------RAKRGLMIF----RLPHRS-YMTTDT---KLLLTTSKGIEKELEI-NVAI---ISNGTFTIDEK
E--LYSVVHPQ-
>tr|A4S991|A4S991_OSTLU Uncharacterized protein OS=Ostreococcus lucimarinus (strain CCE9901) GN=OSTLU_28121 PE=4 SV=1
-EDDSPPKDNILTLSERGYVKRICPKNFGAQNRGTR---RSK--ND-ELSKAMHCKDSDQILFFSDRGRVQKLSAKAIPQE-LNTIGVPATSLL-NFN-Q
N--AMLSTNE-ADDQVVVMLTSQGKVSVASA--ASM-GHKGKKVITLD-D-RLQQ---R--SDHLFITGTAGKGL------FRVVKSACRPISGIKT-M-
-GVAEAVVED-GPFILFTTKKGKGKVVAA-SYR-LGRGRSGVMCM--KGDDALAI-LVDRIG-TDEVLLSTTGGISNRIAV-DLPK-SD---GAAIIKLD
T-ALKSANLLP-
>tr|K1ZJE0|K1ZJE0_9BACT DNA topoisomerase (ATP-hydrolyzing) (Fragment) OS=uncultured bacterium (gcode 4) GN=ACD_63C00028G0004 PE=4 SV=1
EEDLVPNEEIIISMTKGGYIKRMVTQTYKTQRRGG-G--QMK--ED-IIERLFWTMSHSNILFFTNKGRVFQTKAYEIPET-RQAKGQAIVNFL-QSE-E
K--GVIYLD---DVRFLAMTTMKGLTKKVDIGGFEN-R-SGLIAIKLK--DELRW---TN---EIMIVTAKGQAI------IRPMGRNAFGVRGIRLKG-
-DVIGMDVLKKSLQVLTISENGYGKRSDL-SYK-QRRGGSGIKTT---TAKTGKV-SMKILS-KYDILVISANGQVIRTHI-DISI-GR---GVRIMRLD
--KIASVTVI--
>tr|A0A0G0S479|A0A0G0S479_9BACT DNA topoisomerase (ATP-hydrolyzing) (Fragment) OS=Parcubacteria bacterium GW2011_GWC2_40_31 GN=UT97_C0012G0001 PE=4 SV=1
MDDLVPAEEQVMVLTKGGYIKRTDTESYKAQKRGG-G--IID--ED-FVNIFLTVNTHDDLLFFSDKGKVYQIKMYELPEK-RATKGKSIMNFL-STE-E
R--SALVMP--NEEKFLVMVTKKGVVKKSDAANFKD-R-SGIVAIGLD--DELKF---A---DLVIMATKNGQSI------VRSMGRTAGGVRGISMD--
KDVVGADVVQSDFFLLNMGEKGYGKKTEV-NYR-QKRGGSGIKTF---TDKTGKM-VSTVVG-TKEMIAISQKGQVIRTSL-QVPV-GR---GVRIMRLK
G-KIASLTCL--
>tr|A0A0A9J9L6|A0A0A9J9L6_ARUDO GYRA OS=Arundo donax PE=4 SV=1
-IDVIPNEEVLLILSEKGYVKRMNPNTFNLQNRGTI---SGK--ND-SMSDFIVSQTHDHVLYFSDKGIVYSARAYKIPET-RTAAGTPLVQLL-SSG-E
R--SIIPVS----DQYLVMLTVNGYIKKVPLNAFST-RSTGIISIQLV-D-ELRW---G--DDLVALASQKGMVI------LRALGRKTRGVFAMRL-K-
-E---------PPWLLFIAENGLGKRVPL-AFR-SNFNRVGLQGI--PDCLAAVV-GFSLTD-DEQVVLVSQSGNVNRIKV-DISI-SR---GVILMRLE
A--IQSASLIS-
>tr|A0A0K9NQN5|A0A0K9NQN5_ZOSMR DNA gyrase subunit A OS=Zostera marina GN=ZOSMA_705G00010 PE=4 SV=1
-IDVIPNDEMLLAFSKKGYVKRMKSGTFALQHRGTI---SGK--ND-NMSDFLVCHAHDHILYFSDRGIVYSARAFRIPET-RNAAGTPLVQLL-SSG-E
R--SIIPVS----EQYLIMLTVNGYIKKVSLNLFSA-RVTGIIAIQLA-D-ELKW---T--DDLIAIASQNGMVL------LRSIGRVTKGGTSMRL-K-
-N---------PPWLLFISESGFGKRVPL-NFK-TSFKRRGYKGY--QEQLSAVI-GFNLSE-DEQVVLVSQSGTVNRFKV-DISI-SR---GVILMRLE
G--IKSASLIS-
>tr|A0A0J8P4C0|A0A0J8P4C0_STAHO DNA topoisomerase 4 subunit A OS=Staphylococcus hominis GN=parC PE=3 SV=1
KEVIVPSEEVVLSVTRHGYIKRTSTRSFNASG--V---------GD-SLLKY-QTNTQDTALVFTNKGRYLFIPIHKIAD-----LGQHVSQIVPL-ENE
R--DVFNEK----KAFYIIATRNGMIKKSNQSLFK----KPLIATKLK-DEV-VN---T--EQMITVITHKGMSL------L--TGLRAAGVKSINLK--
-DVIMTDTVDQ--SIIMATQRGAIKRIAKD------RAQRGITLL----KLPHRV-AAYVVR---YYTLYSDKH-AETGEI-NIHL---YTNGSFVVDTN
F--VKSMIIN--
>tr|D4FJ99|D4FJ99_STAEP DNA topoisomerase 4 subunit A OS=Staphylococcus epidermidis M23864:W2(grey) GN=parC PE=3 SV=1
KEVMVPSEEVILSLTQHGYIKRTSTRSFNASG--V---------GD-RLLKH-ESNTQDTVLVFTNKGRYLFIPVHKLAD-----LGQHISQIVPI-DDE
E--NVYNEK----EAFYIMATKNGMIKKSSASQFK----KPLINMKVK-DEL-IN---E--DQLITVLTHKGMSL------L--TGLRAAGVKSINLK--
-DVVMTEDVND--SIIMVTQRGAMKRIDFN------RAQRGITLL----KLPHRV-AGAVVK---KYIVFSQHH-EEYGNI-DVHL---YTNGSFIIDTD
F--VESMILE--
>tr|A0A0G3W1T9|A0A0G3W1T9_STACP DNA topoisomerase 4 subunit A OS=Staphylococcus capitis subsp. capitis GN=parC PE=3 SV=1
KEVMVPSEEVILSVSHHGYIKRTSTRSFNASG--V---------GD-RLLKY-QENTQDTVLVFTNKGRYLFIPVHKLAD-----LGQHVSQIVPI-DDE
Q--DVYNEK----DAFYVMATKNGMIKKSSVSQFK----KPLVGMKVK-DEI-VN---E--DQLVTVLTHKGMSL------L--TGLRAAGVKSINLK--
-DVVMTESVSD--SILMITQRGAIKRISYK------RAQRGITLL----KLPHRV-DAAVVK---TYTVFSNNH-EESGNI-EVHL---YTNGSFIIDVD
F--VVSMTLE--
>tr|E6M7R8|E6M7R8_STALU DNA topoisomerase 4 subunit A OS=Staphylococcus lugdunensis M23590 GN=parC PE=3 SV=1
KEVMVPSEDVIMSVTAQGYIKRTSTRSFNASG--V---------GD-RLLKY-QENTQDTILVFTNKGRYLFIPVHKLAD-----LGQHVSQLVAI-EDE
Y--NVYNEK----EAFYIMATRNGMIKKSHAGLFK----KPLVAMKVK-DEI-IS---T--DQIITVLTHKGMSL------L--TGLRAAGVKSINLK--
-DVVMTEVVEA--TIIMATQRGAIKRIDFK------RAQRGITLL----KLPHRV-AGHVVT---EYIIYSESH-VEEGLI-DIHK---YTNGSFIVDTT
F--VINMTIQ--
>tr|A0A069FU15|A0A069FU15_STAAU DNA topoisomerase 4 subunit A OS=Staphylococcus aureus subsp. aureus CO-98 GN=parC PE=3 SV=1
KEVMVPSEDVVLSITRQGYIKRTSTRSFNASG--V---------GD-SLLKY-QTNTQDTVLVFTNKGRYLFIPVHKLAD-----LGQHVSQIVPL-DYE
T--DVYNEQ----DAFYVLATRNGMIKKSNVSLFK----KPLVAMKVK-DEL-IN---N--DQLISVLTHKGMSL------L--TGLRAAGVKSINLK--
-DVVMTDVVDS--SIIMATQRGAVKRISYK------RAQRGITLL----KLPHRV-AGYVVK---MYTLYSESH-SEEGQI-DIHL---YTNGSFVVDVK
F--VLDMTID--
>tr|G5JHU2|G5JHU2_9STAP DNA topoisomerase 4 subunit A OS=Staphylococcus simiae CCM 7213 GN=parC PE=3 SV=1
KEVMVPSEDVVLSLTRHGYIKRTSIRSFNASG--V---------GD-SLLKF-QENTQDTAIVFTNKGRYLFIPIHKLAD-----LGQHVSQIVPI-DDE
A--DIFNEK----NAFYIFATRNGMVKKSTVPQFK----KPLIAIKLK-DEV-IN---E--DQLITVITHRGMSL------L--IGLRAAGVKSINLK--
-DVIMTEGIHD--SILMATQRGSLKRIGFK------RAQRGITLL----KLPHRV-AAHVVT---QYKIYSTTN-EEVGMI-DIHK---YTNGSFIVDVD
F--LIDMYVD--
>sp|Q5HG64|PARC_STAAC DNA topoisomerase 4 subunit A OS=Staphylococcus aureus (strain COL) GN=parC PE=3 SV=1
KEVMVPSEEVILSMTRHGYIKRTSIRSFNASG--V---------GD-SLLKH-QENTQDTVLVFTNKGRYLFIPVHKLAD-----LGQHVSQIVPI-EDE
V--NVFNEK----DAFYVFATQNGMIKKSTVPLFK----KPLIATKVK-DDL-IS---E--DQLITVITNKGMSL------L--TGLRAAGVKSINLK--
-DVVMTEGVSE--TILMATQRGSLKRISFK------RAQRGITLL----KLPHRV-AAHVVT---QYTLYSKSN-EEHGLI-DIHK---YTNGSFIVDTD
F--VIDMYIS--
>tr|A0A0H2HUP1|A0A0H2HUP1_STAAU DNA topoisomerase 4 subunit A OS=Staphylococcus aureus GN=parC PE=3 SV=1
KEVMVPSEEVVLSLTRHGYIKRTTTRSFNASG--V---------GD-SLLKY-LDNTQDTALVFTNKGRYLFIPVHKLAE-----LGQHVSQIVSI-DDE
Q--DVFNEK---HEAFYIMATRNGMIKKSSVPQFK----KPLIAMKVK-DEV-IN---E--DQLITVITHKGMSL------L--TGLRAAGVKSINLK--
-DVVMTQMINH--SVMMATQRGAIKHIGFK------RAQRGITLL----KLPHRV-AADVVR---TYTLYSDNN-QESGEI-SIHK---YTNGSFIVDID
F--VKGMYLQ--
>tr|Q49XE9|Q49XE9_STAS1 DNA topoisomerase 4 subunit A OS=Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229) GN=parC PE=3
KEVMIPSETVIMSVTKHGYIKRTSLRSYNASG--V---------GD-VLMKH-QENTLDTALVFTNKGRYLFIPVHKLAE-----LGQHVSQIVPL-DGE
F--DAYCES----DAFYILATRHGMIKRSNVSMFK----KPLVAMKVK-DEI-IN---D--TQLITVITNKGMSL------L--TGLRAAGVKSINLK--
-DAVLTQVISA--SILMATQRGSLKRIGFK------RAQRGITLL----KLPHRV-AADVIQ---TYTIYSDKQ-QESGAI-DIHL---YTNGSFIVDTS
F--IIDLEVN--
>tr|A0A085UHU7|A0A085UHU7_9STAP DNA topoisomerase 4 subunit A OS=Staphylococcus agnetis GN=parC PE=3 SV=1
KEVIVPSETVVMSLTQEGYIKRTSLRSFNASG--K---------KD-SVLTI-QENTQDTALVFTSKGRYLLIAVHKLPD-----LGQHVSQIVPI-DDE
K--QAYVVS----DEAIITATRNGMIKKSLLSGFK----KPLVAAKVK-DDV-VA---P--LQLITLFTHKGMSL------L--TGLRAAGVKAINLK--
-DVVLADTIDS--SILIATQRGALKRIKAS------RAQRGITVL----KLPHRV-DAKVCR---RFILHSDRH-QFEGNI-DIHL---YTNGSFVVDVT
F--IKHLEIQ--
>tr|A0A0K1A7M3|A0A0K1A7M3_9STAP DNA topoisomerase 4 subunit A OS=Staphylococcus schleiferi GN=parC PE=3 SV=1
KEVIVPSETVMLSVTQEGYIKRTSLRSFNASG--K---------QD-GVLKI-LENTQDNALVFTNKGRYLFIPVHKIAD-----LGQHVSQIVPI-DDE
R--DCYVVS----QSAIITATRQGMIKKSLLSGFK----KPLVAAKIK-DEL-IS---S--SQLLTFLTFKGMSL------L--TGLRAAGVKGINLK--
-DVVMVNTVSP--TILIATQRGSLKRIAFK------RAQRGITLL----KLPHRV-SARVCQ---RYKLISQND-TFEGEI-DIHL---YTNGSFVVDTT
F--IENLFVE--
>tr|B9EBV8|B9EBV8_MACCJ DNA topoisomerase 4 subunit A OS=Macrococcus caseolyticus (strain JCSC5402) GN=grlA PE=3 SV=1
KEILVPNEETVISITREGYIKRTSPRSFNASG--V---------DD-QLLAY-HENLQHITLVFTDKGRYMYIPNHQLPE-----LGTHISQIVPI-DDE
R--HMITVT----EVKILAATRNGMIKLSSLKDFE----RPLINMKLK-DVV-N----H--SEHILVVTKQGMSL------L--TGLKAAGVKSINLK--
-DVITTEIIYP--SLLIATQRGAMKKMDIQ------RAQRGLMIL----KLPHHI-GAYIIT---AYTL-VSEHHEKHGKT-AIRK---YTNGSFIIDEK
F--VVKLYINS-
>tr|B0B0L4|B0B0L4_STAPS DNA topoisomerase 4 subunit A OS=Staphylococcus pseudintermedius GN=grlA PE=3 SV=1
KEVIVPSETVMLSLTQEGYIKRTSLRSFNASG--K---------RD-GVLKI-IENTQDYAMVFTNKGRYLLIPVHKLPD-----LGQHVSQIVPI-EDE
R--DCYTVS----ERAIITATRQGMIKKSLLSGFK----KPLVAMKVK-DAL-IS---P--SQLITLLTHRGMSL------L--TGLRATGIKAINLK--
-DVVLADHIQT--TILIATQRGALKRIGFK------RAQRGITLL----KLPHRV-AARVCR---QYRLVSQQD-ETTGLI-DIHL---YTNGSFVVDTS
F--IEDLYVD--
>tr|A0A0A8HTK3|A0A0A8HTK3_STAHY DNA topoisomerase 4 subunit A OS=Staphylococcus hyicus GN=parC PE=3 SV=1
KEVIVPSETVMMSLTREGYIKRTSLRSFNASG--K---------ED-HILTI-QENTQDTALVFTSKGRYLLIAVHKLPD-----LGQHVSQIVPI-DDE
S--QAFVVS----DEAIITATRNGMIKKSLLSGFK----KPLVAAKVK-DDV-IA---N--LQLLTIFTHKGMSL------L--TGLRAAGVKAINLK--
-DVVMVNTIDY--TILIATHRGALKRIKAS------RAQRGITIL----KLPHRV-DAKVCR---FFTLCSDSN-QFDGNI-DIHL---YTNGSFVVDVA
F--IKHLEIQ--
>tr|A0A0E4H3F9|A0A0E4H3F9_9STRE DNA topoisomerase 4 subunit A OS=Streptococcus sp. FF10 GN=parC PE=3 SV=1
TASLIAEEETFVSITRGGYIKRTSPRSFNSSA--M---------ED-ELIFL-EKKTTQHLLIFTNFGNVIYRPIHELTD-----IGEHLSQTITT-GEE
Q--YAEIVD----QT-YFAVTKLGQIKRFERKEFA----KSLKFAKLK-ADSIVT---L---DDVILVTHNGYAL------V--IGAKAAGVKAINLK--
-DVASAFIANT-KSMYVLTQRGSLKRMSIN------RAGRGLQVL----RLPHRF-LAGPVFVQQILQVQSQTGQVEEVNL-NLNL---TSNGSFISDTI
D--VFAAKVK--
>tr|A0A081JHN2|A0A081JHN2_STRMC DNA topoisomerase 4 subunit A OS=Streptococcus macedonicus GN=parC PE=3 SV=1
VASLIVEEDTFVSVTKGGYIKRTSPRSYNAST--V---------DD-ELIFV-AHKTTQHLLIFTNLGNVIYRPINELTD-----IGEHLSQTITN-ADE
Y--YAEIVD----QT-YFAATKLGQIKRFERKEFT----KSVKYAKLK-DDSVVT---A---DDVMIMTHNGYAL------V--VSAKAAGVKAINLK--
-DVASAFVANT-DSFFILTQRGSLKRMATE------RANRGLQVL----RLPHRF-MAGPVH-VETLEVRSNKGAVYQAIL-DLNL---TSNGSFISDKI
D--VFSARIK--
>tr|A0A0C2UED4|A0A0C2UED4_BACIU DNA topoisomerase 4 subunit A OS=Bacillus subtilis subsp. subtilis GN=parC PE=3 SV=1
LEVMVASEDVYVTVTKDGYLKRTSQRSFAASN--G---------TD-RMLHQ-FENTTDVLLLFTNKGSYIYCPVHQLPD-----MGQHFSNLITI-DDE
T--KAIPIK----SAYLLFFTKNGMVKKTELTHYK----KALVALNLK-DEL-I----H--ESQIFMATHLGYGL------V--VGARAAGVKGINLK--
-DVVSGEILQQ-DSIVLFTQRGAVKRMSLS------RAKRGVVML----RLPHRV-ALFACG---RLMAETEKGDRKELQA-ELRT---YSNGSFFFDEE
S--VTAVWRLH-
>tr|A0A080UK80|A0A080UK80_BACIU DNA topoisomerase 4 subunit A OS=Bacillus subtilis subsp. niger GN=parC PE=3 SV=1
LEVMVASEDVYVTVTKDGYLKRTSQRSFAASN--G---------TD-RLLHQ-FENTTDVLLMFTNKGSYIYCPVHQLPD-----MGQHFTNMISI-DDE
T--KAIPIK----SAYLLFFTKNGMVKKTELTHYK----KALVALNVK-DEL-T----H--ESQLFIATHLGYGL------V--VGARAAGVKGINLK--
-DVVSGQILHE-DSLVLATQRGAVKRMSLS------RAKRGVIML----RLPHRV-AVFACR---RLMFETEKGETKELLV-ELRT---YSNGSFLIDEE
A--VIAAWRLE-
>tr|A0A0M3R9B9|A0A0M3R9B9_9BACI DNA topoisomerase 4 subunit A OS=Bacillus gobiensis GN=parC PE=3 SV=1
LEVVVASEDVYVTVTKDGYIKRTSQRSYAASN--G---------TD-RLLHQ-FENTTDTVLLFTNKGSFIYCRVHELPD-----LGQHFTNLIPI-DNE
S--KAIPIK----DEYLVFITKNGMAKKTELAQYK----KPLVAINLK-DEV-V----H--EKNLFIATYLGYGL------I--VGARAAGVKGINLK--
-DVVSAQLADE-ALLALVTQRGAFKRMSIS------RAKRGVQML----RLPHRK-TVIVCD---QIGIESEKGIRETVDV-NYRN---YSNGSFIIDED
A--VTDVWLEL-
>tr|M5P6M6|M5P6M6_9BACI DNA topoisomerase 4 subunit A OS=Bacillus sonorensis L12 GN=parC PE=3 SV=1
LEVMVASEDVYVTVTKDGYIKRTSQRSFAASN--G---------TD-RLLCQ-LENTTDVLLLFTNKGSYVYCPVHQLPD-----LGQHITNIISI-DDE
S--KAIPVK----SEYLLFFTKNGMAKRTPLLQYK----KALVALNLK-DEV-I----H--AKDVFIATHSGYGL------V--VGARAAGVKGVNLK--
-DAVSGQILED-DVLVLVTQRGAVKRMNRT------RAKRGVLML----RLPHRA-GLLACS---QITMQTEKGIIEEMLV-DIKL---YSNGSFIIDED
A--VTDVWISK-
>tr|A0A0A0TRZ3|A0A0A0TRZ3_BACIU DNA topoisomerase 4 subunit A OS=Bacillus subtilis GN=parC PE=3 SV=1
LEVMVASEDVYVTVTKDGYVKRTSQRSFAASN--G---------TD-RLIHQ-FENTTDVLLLFTNKGSYIYCPVHQLPD-----MGQHVTNITTI-DDE
T--KAIPVK----ASYLLFMTKNGMVKRTEMTHYK----KALVALNLK-DEL-V----H--GCQLFIATHLGYGL------V--VGARAAGVKGINLK--
-DVVSGQILHE-DSLVLVTQRGAIKRMNLS------RAKRGVIML----RLPHRV-GVFACA---TIAAETEKGERIETTV-SLRA---YSNGSFFTDED
T--VTDVWRIP-
>tr|F2NCU3|F2NCU3_DESAR DNA gyrase subunit A OS=Desulfobacca acetoxidans (strain ATCC 700848 / DSM 11109 / ASRB2) GN=gyrA PE=3 SV=1
LEDLIPDEDMVVTVSHQGYIKRNPLNLYRSQRRGGKGRTGMSI-EDDFVSQLYIASTHNYFLVFSNLGRIYWLKVHEIPVGSPSARGKAIVNLLNFGS-E
KLTTILPIR----EHYLVMATKRGIIKKTELMNFSR-RSGGLIACTLDEGDELVSVA-TDG-KEVFLGTSLGKIIRFAE--VRDMGRSARGVRGMTVA--
DCIVGMEILSAEGAILTVTANGYGKRTRHEEYRLQKRGGSGLLALRIT-D-NGPVVGIIQVTD-DEIMLITDRGKIIRLPVTGISLIGRVTQGVKLIDTE
-ERVVSIARLA-
>tr|D3PA93|D3PA93_DEFDS DNA gyrase subunit A OS=Deferribacter desulfuricans (strain DSM 14783 / JCM 11476 / NBRC 101012 / SSM1) GN=gyrA PE=3 SV=1
IEDLIPDDEVVVTLSYQGFIKRTPLSNFKSQKRGGKGKTGAGN-KEDFIKDILVTTNHSTLMFFTNKGRIHYLKVYELPELARDAKGKYIANLISLDK-E
KVAAMISTK----DRYIFMCTKEGIVKKTSLDAFSS-RS-GIIAIKLRDGDEIVDAS-ISK-DSIFISTRKGKCIQFNS--VRNMGRNATGVKGITLT--
DKVVSMEAVKGDPLILTVTTKGFGKSSLITDYRIQSRGGKGIKLSKVT-E-TGEIVGARQVKE-DDVMLISKSSKVIRLSVSDIPILGRDTQGVKLMGLD
E--IISFDVIR-
>tr|F8E6E7|F8E6E7_FLESM DNA gyrase subunit A OS=Flexistipes sinusarabici (strain DSM 4947 / MAS 10) GN=gyrA PE=3 SV=1
IEDLIPDDEAVVTITHNGYIKRTPLNSFSAQKRGGKGKSGALS-GDDFIERLIVSSNHSKLMFFTNMGRIYFLKVYELPESAPGTRGRHVSNFIHFSD-E
FIASVLSVSE----KDIVFGTKKGLVKRSPVSLFKS-R-SGIIAIKLRDGDEIVSTD-VAD-DNILIATKNGKAIHFSA--IRSMGRNATGVKGIDLA--
DEVVSMEIAS-APYLLTVTENGYGKCTPVNEYRLQSRGGKGIKLSKVT-S-TGKICGAKQVRS-DDVMLIIKSGKIIRIGVSQISVLSRNTQGVTLMNTG
--YIVSFAVVK-
>tr|E4TI26|E4TI26_CALNY DNA gyrase subunit A OS=Calditerrivibrio nitroreducens (strain DSM 19672 / NBRC 101217 / Yu37-1) GN=gyrA PE=3 SV=1
IEDLIPDTEMVVTITNQGYIKRTPLSFFSSQKRGGKGKSATLS-GEDFIETLIVTSNHSKLLFFTNQGKIHFLKVYELPESAPGTRGRHISNLLSFSQ-E
YIASVVTLSD----KYIFMCTKYGIVKKTAVEEFKS-R-SGIVAMKLRENDELVSTV-TTD-DNITIATRNGKTIQFES--VRDMGRTATGVRGITLE--
DYVVSMEVLT-APFILTVTSNGYGKCSLVSDYRIQSRGGKGLKLSKVT-P-TGPIVGAKQVKE-DDVMLMSKTGKIIRIAVSDIPVLGRDTQGVKLMSVA
--EIVSFAIVK-
>tr|D8FD24|D8FD24_9DELT DNA gyrase subunit A OS=delta proteobacterium NaphS2 GN=gyrA PE=3 SV=1
MEDLIAEEDMVVTVSHQGYIKRNPISLYRAQRRGGKGLTGAKP-EEDFVEHLFVASSHDYFLFFTNKGRVYWKKVHEIPEGGRMSRGKAIVNLLDLKK-E
RLATILPVR----GKYVVMATKMGFVKKTELKAYSH-RSVGTIGLKIRENDELIAVR-SSG-QDIFLTTKEGKSIRFKE--LRSMGRVAAGNIGIKME--
NEVVGMETLGEGATILTVTENGFGKRTNREEYPTQARAGKGVITIKTS-E-NGLVVYAYEVTQ-DELMIITGHGKIIRIRAADISVIGRNTQGVKLIDLG
-GKVVGVAKIM-
>tr|A0A0M1HY33|A0A0M1HY33_STACA DNA topoisomerase 4 subunit A OS=Staphylococcus carnosus GN=parC PE=3 SV=1
KEVIVPSEETILSLSRDGYIKRTSVRSFNANR--V---------GD-ALLSH-LENTQHIALVFTNKGRYLYLPVHKLPD-----LGQHISQLVPI-EDE
Y--DVFTEP----NADYIMATKNGMIKKSELELFK----KPLIAMKLK-DEL-IN---E--DQLITIVTHTGMSL------L--TGLRAAGVKSINLK--
-DVEMTQLIQP--TILMATQRGAVKRIGFK------RAQRGIKLL----KLPHRV-GADVIS---IYTIYSNKD-SFSGKV-DIHL---YTNGSFVVDTD
F--VNALSVSV-
>tr|A0A068E543|A0A068E543_STAXY DNA topoisomerase 4 subunit A OS=Staphylococcus xylosus GN=parC PE=3 SV=1
KEVMVPSETVIMSITKHGYIKRTSLRSFNASG--V---------GD-SIMKY-QENTLDTALVFTNKGRYLFIPVHKLAD-----LGQHVSQIVPL-DGE
Y--NAYCEN----EAFYILATRNGMIKKSNVSMFK----KPLVSMKLK-DEI-IS---S--AQLITVVTNKGMSL------L--TGLRAAGVKSINLK--
-DTVLTDIVTS--KILMATQRGSLKRISFK------RAQRGITLL----KLPHRI-DAAVIT---TYTIYSDKQ-QETGLI-DIHL---YTNGSFIVDTS
F--IKDLEVK--
>tr|K0TSA4|K0TSA4_9STAP DNA topoisomerase 4 subunit A OS=Staphylococcus arlettae CVD059 GN=parC PE=3 SV=1
KEVMVPSENVILSVTRHGYIKRTSLRSFNASG--V---------GD-SLLKY-IDNTLDTALVFTNKGRYLFIPVHKLAD-----LGQHVSQIVPL-EDE
F--DAYCEN----DAYYIIATRNGMIKKSNVSMFK----KPLVAMKVK-DAV-ID---S--EQTLTVLTHKGMSL------L--TGLRAAGVKSINLK--
-DVVLTQIVAP--TILMATHRGALKRIDYR------RAQRGITLL----KLPHRV-AACVIQ---SYTIFSTNQ-QESGLI-DIHL---YTNGSFVVDVD
F--INNLVVE--
>tr|I7KMZ7|I7KMZ7_9STAP DNA topoisomerase 4 subunit A OS=Staphylococcus equorum subsp. equorum Mu2 GN=parC PE=3 SV=1
KEVMIPSETVIMSVTKHGYIKRTSLRSFNASG--A---------GD-ELLKY-QENTLDTALVFTNKGRYLYIPVHKLSE-----LGQHVSQIVPI-DGE
H--DVFCER----EAFYVLATRDGMIKKSNVSMFK----KPLVSMKLK-DEI-IN---E--PQLITVLTHKGMSL------L--TGLRAAGVKSINLK--
-DAVLTQLISE--SILMATQRGSLKRIGFK------RAQRGLTLL----KLPHRV-AAEVVQ---QYTIYSNKQ-QETGDI-DIHL---YTNGSFIVDIN
F--VESLVVK--
>tr|A0A0D0SNL6|A0A0D0SNL6_STAGA DNA topoisomerase 4 subunit A OS=Staphylococcus gallinarum GN=parC PE=3 SV=1
KEVMIPSETVVMSITKHGYIKRTSLRSFNASG--I---------GD-ALLKQ-QENTLDTVLVFTNKGRYLFIPVHKLAD-----LGQHVSQIVPI-DGE
Y--DIYGES----EAYYILATKNGMIKKSNVSMFK----KPLVAMKLK-DEI-ID---S--TQLLTVITNKGMSL------L--TGLRAAGVKSINLK--
-DVVLTQIISE--TILMATQRGSLKRISFK------RAQRGITLL----KLPHRV-AAKVVN---NYTIYSSKD-QETGLI-DIHL---YTNGSFIVDVT
F--VEGLDLK--
>tr|A0A0M2P4C2|A0A0M2P4C2_STACC DNA topoisomerase 4 subunit A OS=Staphylococcus cohnii subsp. cohnii GN=parC PE=3 SV=1
KEVMVPSENVIMSITKHGYIKRTSLRSFNASG--V---------GD-TMLKY-QENTLDTALVFTNKGRHLYIPVHKLSE-----LGQHVSQIVPI-DGE
H--DVYCES----DVFYILATRNGMIKKSNVSMFK----KPLVSMKLK-DEV-IN---D--PQTITVLTHKGMSL------L--TGLRAAGVKSINLK--
-DVVLTQIVNE--TILMATQRGSLKRIRFN------RAQRGITLL----KLPHRV-AANVVQ---TYTVYSKQH-EESGNI-DIHL---YTNGSFVVDVK
F--VVNMSVK--
>tr|H0DHN5|H0DHN5_9STAP DNA topoisomerase 4 subunit A OS=Staphylococcus pettenkoferi VCU012 GN=parC PE=3 SV=1
KEVMVPSENVVVSMTRDGYIKRTSLRSFNASG--V---------GD-GLLKY-LENTLDTVLVFTNKGRYLYIPVYKLAD-----LGKHISQIVAI-DDE
S--DVYCER----DGHYILATRNGMIKKSNVSMFK----KPLVAMKVK-DEL-ID---T--PEMITVLTHKGMSL------L--TGLRAAGVKSINLK--
-DVVLTQTVNE--TILMATQRGALKRIGYS------RAQRGITLL----KLPHRV-GADVIS---QYTIISERT-SETGNV-DIHL---YTNGSFVVDVK
F--VTSLIIE--
>tr|A0A033V433|A0A033V433_STAAU DNA topoisomerase 4 subunit A OS=Staphylococcus aureus C0673 GN=parC PE=3 SV=1
KEILVPSEETIVSVTHDGYIKRTSNRSYIASG--V---------GD-YLLMH-EKNTQDTLIVFTNKGNYLFIPVHEIVD-----LGKHISQMIPI-DDE
R--SVNKET----SSNYIIATKNGMIKKSTNDKFK----KPLVAIKLK-DEV-V----L--DELITVITEKGMSL------L--IGLKAAGVKSINLK--
-DVVMTDKLPN--SVFIVTDRGSVKRMKAE------RSQRGLMIL----KLAHRV-FARTVS---TCVI-ISEKDQVKVNT-DFNS---YTNGRFVVDEN
F--VIDAYFEE-
>tr|K9AIF3|K9AIF3_9STAP DNA topoisomerase 4 subunit A OS=Staphylococcus massiliensis S46 GN=parC PE=3 SV=1
KEVVVPKEDVIISLTHDGYIKRTSIRSFNASG--V---------ED-TLLKY-IEHTQQTLLVFTNKGRYLNIPVHKLSD-----LGQHVSQIVPI-DDE
K--NMYTEN----DGYYVLATRNGMIKKSNIGLFK----KPLIAMRMK-DDV-IS---T--DKTLTVLTHKGMSL------L--TGLRAAGVKSINLK--
-DVVMTDAVSE--TILMVTQRGAIKRIGYN------RAQRGLTLL----KLPHRV-DAKTCR---SYEIVSTSGKVHEGAN-DIHL---YTNGTFIVDIK
F--ISYMIISD-
>tr|A0A0D6XPJ9|A0A0D6XPJ9_9STAP DNA topoisomerase 4 subunit A OS=Staphylococcus microti GN=parC PE=3 SV=1
KEVLVPSEVVMVSVTSEGYIKRTSLRSYSASG--K---------ND-YVLKC-LENTQDTALVFTNKGRYLSIPVHKLPE-----LGQHISQLASI-DDE
V--ACDVVS----SEAVITATRNGMIKMTTLSHYK----KPLVAMKLK-DVV-IA---N--SDFVTLLTHKGMSL------L--TGLRTGGVKAINLK--
-DVVMADLVGE--TILIATQRGALKRIGFN------RAQRGLTLL----KLPHRV-AARVCR---QYHLVSDES-VHDGQI-KIHL---YTNGSFVVDTA
F--IRHLFISE-
>tr|A0A078M750|A0A078M750_9STAP DNA topoisomerase 4 subunit A OS=Jeotgalicoccus sp. 13MG44_air GN=parC PE=3 SV=1
KEQLIAKEDTVVSLTKEGYVKRTSLRSYNASK--P---------GD-RILFT-SMNTLEQLLVFTNYGNYMIIPVHGLQD-----MGQHLSSRFNL-KGE
E--FARTIS--EN-ISVVMASKRGQVKQTLLSEFE----RPIVNMKLK-D-EVIG---E--KESLLFVTEKGLTL------V--TGLKSQGVKAMNVK--
-DLVFGELIPEEGNLVTVSSRGAVKRTSLD------RAQVGSMLY----KIPHRV-AASVTD--DQTIELISETNVHTLRA-EVRL---YSNGSFVVEED
F--VAH----A-
>tr|U7PEU4|U7PEU4_STASI DNA topoisomerase 4 subunit A OS=Staphylococcus simulans UMC-CNS-990 GN=parC PE=3 SV=1
KEVIVPSEETILSLSKDGYIKRTSIRSFNANK--V---------GD-SLLRY-VENTQHIALVFTDKGRYLYLPVHKLSD-----LGQHISQLVPI-EDE
R--DVFTEP----EADYLMATKNGMIKKSELGLFK----KPLIAMKLK-DVV-IN---E--PQLLSVITHTGMSL------L--TGLRAAGVKSINLK--
-DVVMTQVVHP--TILMATQRGAVKRIGYQ------RAQRGIKLL----KLPHRV-GADVIE---TYTLYSNKD-TFTGTV-DVHL---YTNGSFVVDVD
F--VEALSVSD-
>tr|A0A069F5G1|A0A069F5G1_STACR DNA topoisomerase 4 subunit A OS=Staphylococcus chromogenes MU 970 GN=parC PE=3 SV=1
KEVIVPSETVVMSLTREGYIKRTSLRSFNASG--K---------KD-AILTI-QENTQDTALVFTNKGRYLLISVHKLPD-----LGQHVSQIVPI-DDE
T--QAYVVS----EEAIVTATRNGMIKKSLLSGFK----KPLVASKVK-DEI-VS---N--LQLITLLTHKGMSL------L--TGLRAAGVKAINLK--
-DVILVDTVNN--TILIATQRGALKRIKAS------RAQRGMTLL----KLPHRV-AARVCH---TFTLCSENE-HYQGQI-DIHL---YTNGSFVVDVT
F--IKHLEIDA-
>tr|A0A0J6CYQ7|A0A0J6CYQ7_9BACI DNA topoisomerase 4 subunit A OS=Anaerobacillus macyae GN=parC PE=3 SV=1
LEVMVPSEDVIVTVTEDGYVKRTSPRSYAASN--G---------TD-TLLRQ-FDNTTNTILLFTNKGSYLYLPVHELPE-----LGQHVANIVSI-EDE
R--EAMEIQ----DRYLVFVTKQGMIKKTELSHYK----KPLMALKLK-DEL-V----Y--SKEVFIATNFGYGL------I--VGQRASGVKGINLK--
-DVVSGIIYE-KYDLFLVTHRGAVKKMQLS------RAKRGVVML----RLPHRI-GVEAVT---LILIRTKKGEPVEVDP-TYRP---YSNGSFVIDVS
T--AIELKKKS-
>tr|A0A0M2UE88|A0A0M2UE88_9FIRM DNA topoisomerase (ATP-hydrolyzing) OS=Clostridiales bacterium PH28_bin88 GN=SY88_01460 PE=4 SV=1
VEVMVASEDVVVAVTNQGYIKRTSIKSYQRSG--AD--------AD-FVRFL-VSNTTETVLLLTARGTAYSLPVHQLPE-----RGSALVNVISL-PDD
R--ALIPVK----ELSLIFFTAKGLVKKTDLSEYA----TGIVAIKLA-DRV-V----I--SGEILQSTINGMCI------V--MGRNAAGVKAIRLA--
-DVLAAQEVKAGQEVILMTDWGKGKRVTLE------RAGKGVLTG--PRQEAMEV----DAS---ALLVVQKSGRITRLQS-AIPA---EKAFTPLVDVI
G--IASMVPSY-
>tr|K9ZWD9|K9ZWD9_DEIPD DNA gyrase subunit A OS=Deinococcus peraridilitoris (strain DSM 19664 / LMG 22246 / CIP 109416 / KR-200) GN=gyrA PE=3 SV=1
KEDLIAVEDMVITMTRAGYLKRTKLDAFRAQGRGGRGASGGRL-EEDTNTRVMVGSTHDFLLFFTDQGRVFHEKIYDLPEVGRDAKGTYIKNLLPGR-TE
SIASVMSIK---QEGSFVFATKRGMIKKTLIRDYANITSAGLIAINMMEGDELIGVG-VKDGEHVVLATAEGQAMRFDA--VRDTGRATQGVIGIRLR--
-KVVSMALVPSETELLAVSECGLGKRTPLSEYPAKGRGGQGVITL--TR--TGNLVTLAHVSGDEELMVLTEKGVVIRTRVEELRVSGRNSQGVKVMDIG
-GRVISAFPVK-
>tr|A4XFI6|A4XFI6_CALS8 DNA gyrase subunit A OS=Caldicellulosiruptor saccharolyticus (strain ATCC 43494 / DSM 8903 / Tp8T 6331) GN=gyrA PE=3 SV=1
EEELIQEQDTVITLTHFGYIKRLPLDTYKSQKRGGKGITGIST-EEDFVEEVFVTTTHHYILFFTDKGKAYRLRAYEVPES-RQAKGTAIVNLIQIGK-E
KITACMTVK---EGF-LMMCTKNGTIKKVLLSEFEN-TKAGKKAITLAEDDCLIDVK-TSG-DEMVLVSSGGYCVVFNE--VRVMGRSAQGVKGMTLE--
-GVVGMEKASD-KYLLCVTENGFGKRSDIEEYRKTKRGAKGVLTYKVT-E-TGRIVDIKMVNE-DEIMLCSTEGIFIRLEMSQVPVQGRNTQGVKLMRID
DSKVSSIARIK-
>tr|K1KXT7|K1KXT7_9BACI DNA topoisomerase 4 subunit A OS=Bacillus isronensis B3W22 GN=parC PE=3 SV=1
RDVLVPSEEVVVTVTKDGYVKRTSLRSHSASN--G---------SD-YLLYE-ANNTQHHLLLFTSKGHYIYQPVHELPD-----LGQHISSIVPI-DNE
E--EVIGIE---PNVYVFTATKEGQIKRSALADYI----KPIKTMNLK-DEM-I----R--QEEVLLSTNTSYTI------L--TGVKTAGVKGIIVK--
-ELAAVALLKPQ-ELVIVTQRGAVKRMLLS------RAKRGVVIL----KLPHRF-TILVVN---TFTIETEKGVQETISV-SLTR---YSNGSLRIDTE
D--ISRAYVEK-
>tr|A0A0M0LA72|A0A0M0LA72_9BACI DNA topoisomerase 4 subunit A OS=Bacillus koreensis GN=parC PE=3 SV=1
LEVMIPSEDVMVTVTKDGYVKRTSLRSYAASN--G---------TD-RFLLK-QGNTTDTMLLFTNKGNYLYMPIHELPD-----MGQHVTNIIPI-DKE
E--KAIPIH----PKFLLFVTKNGMVKKTELAHYK----RALVGVNVK-DEV-V----H--QQDVFLATHDGYGL------V--VGPRASGVKGINLK--
-DVVAGKVFEEQPKLVMATQRGAVKKLSI-------RARRGLVMV----KLPHKV-GFEFIT---WYYLVTDKHHIEQIDP-SMRV---YGIGSYVVDQS
A--VSAVWIEP-
>tr|A0A0Q9GHQ0|A0A0Q9GHQ0_9BACI DNA gyrase subunit A OS=Bacillus sp. Root147 GN=ASE51_11185 PE=4 SV=1
LEVMVPSEEVMVTVTKDGYVKRTSLRSYAASN--G---------TD-RILAK-YENTTETLLIFTNKGNYLYMPVHELPD-----MGQHIMNIVPI-DEE
Q--RAIPVK----NQYLLFFTKNGMVKKSELLQYK----KALVAVNLK-DEV-V----Y--KKQVFIATRSGYGL------I--VGTRASGVKGINLK--
-DVVSGAIFDESTELFIATQRGAVKKTKI-------RAKRGLVMV----RLPHQA-KVKLIS---YMIVESSKGQIEQVDP-TMRA---YSNGSFVLDQS
A--LVDVWLEE-
>tr|A0A0H4KYN4|A0A0H4KYN4_9BACI DNA topoisomerase 4 subunit A OS=Bacillus endophyticus GN=parC PE=3 SV=1
LEVMVPSEDVMVTVTSDGYVKRTSLRSYNASN--G---------TD-HILGC-FENTTETLLLFTNKGSYLYMPIHELPD-----LGQHVSSLIPL-DEE
H--QALPIE----EDYLLFATKNGMVKRTELKSFK----RPLMALNVK-DEV-V----M--NSRILLGTKAGYVL------I--VGPRAAGVKGINLK--
-DVIGAETFITDTQAIFVTQRGAVKKMNL-------RAKRGTMIL----RVPHNI-GFTIVK---AIRIESAKGMTEKVIP-NIRV---YSNGSFIMDEA
V--IISMWIEK-
>tr|N0AZJ2|N0AZJ2_9BACI DNA topoisomerase 4 subunit A OS=Bacillus sp. 1NLA3E GN=parC PE=3 SV=1
LEVLIANEDVIVTVTRQGYVKRTSQRSYAASN--G---------SD-RLLAR-LDNTTDVLLLFTNKGNYLFCPVHELPD-----LGQHIANIIPI-DDE
S--KAIPIE----NQYLLFVTKNGMVKKTELIQYK----KPLTAINLK-DQV-I----Y--KNDLFLMTHYGYAL------V--VGARAAGVKGINLK--
-DVISGKILS-KRAIVIATQRGAVKKMKLS------RAKRGLVQL----RLPHRI-GFVLVQ---DIYIQSEKGTIESINA-SIRN---YSNGSFLLDES
S--TVEIWVIE-
>tr|A0A0M2T1C4|A0A0M2T1C4_9BACI DNA topoisomerase 4 subunit A OS=Bacillus sp. SA2-6 GN=parC PE=3 SV=1
LDVLIASEDVIVTITKDGYIKRTSQRSFAASN--G---------TD-RLLAQ-LDNTKDVLLLFTNKGSYMYLPVHELPD-----LGQHIANIVPL-DSE
N--RAIPVS----NLFLLFATRNGMVKKTELKQYQ----KTLTAINLK-DEV-V----H--NASLFLATRLGYAL------V--IGIRAAGVKGINLK--
-DVIAGKLVE-EQSVILVTQRGAVKKMKLS------RAKRGVVML----RLPHKA-GMQIAR---VVFLLSEKQKLATIAP-SINY---YSNGSFILDEN
S--VMEVWKTE-
>tr|A0A0Q3VYE1|A0A0Q3VYE1_9BACI DNA gyrase subunit A OS=Bacillus sp. FJAT-25509 GN=AN960_22750 PE=4 SV=1
REDIIAQEDVIVTVTSEGYVKRTSPRSFSASN--G---------GD-RLIYQ-IETTTDTLILFTSKGNYLYLPIHEMQD-----MGQHVANIIPI-EDE
A--SATVVN---NKDFILFVTKNGVVKRTSIQQLK----KPLVGMSIK-DSL-I----G--TDQVLLATNSGYTL------I--QGLRAGGVKGINLK--
-DVVSADKIS-K-EIFCATHRGAIKKMKLD------RGTRGVKVL----RLPHMI-GVYAIN---MFALLSKSGQFETVDP-DLRN---YSNGSFVMDTD
S--IKTIIRYK-
>tr|A0A0D6ZC30|A0A0D6ZC30_9BACI DNA topoisomerase 4 subunit A OS=Bacillus subterraneus GN=parC PE=3 SV=1
LEVLIASEDVIVTVTKDGYVKRTSQRSYAASN--E---------TD-RLLSR-LNNTKDVLLLFTNKGSYLYLPVHELPD-----LGQHVANIVPL-DDE
E--KAVPIT----NLFFLFVTKNGMVKKSELSLYK----KPLTAINVK-DRV-I----H--NMDLFLASHFGYGL------V--IGIRAAGVKGMNLK--
-DVVGGKIID-NPSIVIATQRGAVKKMKLS------RAKRGVVML----RLPHRI-GVEAVK---ELFFLSEKQQIVSLKA-DLRN---YTNGSFIIDEN
T--LKSVWKRE-
>tr|A0A0R1ZLY7|A0A0R1ZLY7_9LACO DNA topoisomerase IV subunit A OS=Lactobacillus sharpeae JCM 1186 = DSM 20505 GN=FC18_GL000796 PE=4 SV=1
TTVVVPDEQVMVLVSRDGYVKRSSLRSYQAVD--A---------ED-FVMFE-GASTLDHLYIFTSLGNVIYRPVHELTD-----SGEHLSQTV-G-GAE
T--AVYAFK-L-LPGTFVLGTSDGMIKQTSLADLQ----KPMMAMKVK-A-HVTD---E--DQLIFAATTKGYGL------V--TGARAGGVKMINLK--
-DVADFVLADN-QVVAIVTQRGAFKQMPIS------RAKRGLQIL----RLPHRV-AARSV--GTVLDVLTADSTITTINP-NHPT---FGNGSFVLDTD
V--PQYVHVRQ-
>tr|A0A0R1P114|A0A0R1P114_9LACO DNA topoisomerase IV subunit A OS=Lactobacillus kisonensis DSM 19906 = JCM 15041 GN=FC98_GL000161 PE=4 SV=1
TDVLIPDEDVIVMVSHDGYIKRSSIRSYKASG------------DD-YSIFM-KENARDHLFMFTSKGNLIYRPVYEITD-----TGEHISQTI-G-DDE
D--GTFAFN-L-EPGNFLIATDEGHIKQTAFTDLT----HAYTYEKLK-NAKVVA---T--AGQLLLMSRDGLAL------V--NGARTTGVKSMALR--
-DVVDLQLVDETSVVAIVTQRGAFKKLAVK------RARKGVMIL----RLPHRI-DFETIV-HTPLEVLTDRKRVHDILP-EFSV---YSNGSFVIDID
E--PAVIRQKP-
>tr|A0A0R1NE75|A0A0R1NE75_9LACO DNA topoisomerase IV subunit A OS=Lactobacillus rapi DSM 19907 = JCM 15042 GN=FD12_GL000330 PE=4 SV=1
TDVLIPDEDVVVMVSHDGYIKRSSIRSYKAST------------ED-YPIFM-EQNARDHLFMFTSKGNLIYRPVYEIAD-----TGEHISQTI-G-DDE
E--GTFAFN-L-EPGNFLITTDEGHIKQTAFADLK----HAYMYEKLK-DSRVVS---S--AGQLLLISKNGLAL------V--NGSRTTGVKSMDLR--
-DVINLQLVNEDSIVAIVTQRGAFKKLAVK------RARKGVMIL----RLSHRI-DFETIA-HSPLEILTDRKRVHDILP-EFSI---YSNGSFVVDVE
E--PTKIRQKP-
>tr|A0A0R1S6V2|A0A0R1S6V2_9LACO DNA topoisomerase OS=Lactobacillus diolivorans DSM 14421 GN=FC85_GL001188 PE=4 SV=1
TDVMVPDEDVVVMVSHDGYIKRSSLRSYKASS------------ED-YPIFM-EQNARDHLFMFTNKGNLIYRPVHEIAD-----TGEHISQTI-G-DDE
E--GTFAFN-L-ESGNFLIATDDGHIKQTSFQDLK----HAYTYEKLK-NAKVVA---A--SSELLLISHHGLAL------V--NGARTTGVKSMGLR--
-DVTNLQLIQPNSVVAIVTQRGAFKKLAVK------RARKGVMIL----RLPHRV-DFVVID-DQPLEVLTNRARSHDILP-EYSV---YSNGSFVIDVD
E--PKQIRIKP-
>tr|A0A0R1YZN3|A0A0R1YZN3_9LACO DNA topoisomerase IV, A subunit OS=Lactobacillus parafarraginis DSM 18390 = JCM 14109 GN=FD47_GL002883 PE=4 SV=1
TDVIIPDEDVVVMVSHDGYIKRSSVRSYKASG------------ED-YPIFL-KENARDHLFMFTSKGNLIYRPVFEIAD-----TGEHISQTI-G-DDE
E--GTFAFN-L-APGQFLIATDDGHIKRTSLADLA----HAYTFEKLK-SARVVA---P--TGNLLLISKRGLAL------V--NGARTTGVKSQNLG--
-DVVNLQLISDDAVIGIITQRGAFKKLAVS------RARKGVMIL----RLSHRV-DFTVIS-ERPLEVLTDRQRVHDIQP-EFSL---YSNGSFVVDID
E--PISIREKP-
>tr|A0A0R1RMQ4|A0A0R1RMQ4_9LACO DNA topoisomerase IV subunit A OS=Lactobacillus parakefiri DSM 10551 GN=FD08_GL003944 PE=4 SV=1
TDVLVPDEDVVVLVSHDGYIKRSSIRSYKAST------------ED-YPIFM-EQNARDHLFMFTNKGNLIYRPVYELAD-----TGEHISQTI-G-DDE
E--GTYAFS-L-EKGIFLIATDEGHVKQTNFADMT----HAYTYEKLK-GDRVVS---P--TDQLLLISEHGLAL------V--NGARTTGVKSMALR--
-DVTDLQLVKDDGVVAIVTQRGAFKKLAIK------RARKGVMIL----RLPHRV-DFCTIA-DQPLEVRTDHRRVHDILP-DYSL---YSNGSFVIDVD
E--PVSIRPKF-
>tr|F4FV83|F4FV83_LACBN DNA topoisomerase 4 subunit A OS=Lactobacillus buchneri (strain NRRL B-30929) GN=parC PE=3 SV=1
TDVLIPDEDVIVMVSHDGYIKRSSIRSYKAST------------ED-YPIFM-AENARDHLFMFTNKGNLIYRPVFELAD-----TGEHISQTI-G-DDE
E--GTYAFD-L-QPGTFLIATDQGHVKQTGFADMK----HAYTYEKLK-DERVVA---K--AGQMLLISNNGLAL------V--NGARTTGVKSMGLR--
-DVTNLQLVSEDDVLAIVTQRGSFKKLAVK------RARKGVMIL----RLPHRV-DFCRIE-DQPLEVRTDHRRVHDILP-DYSL---YSNGSFVIDVD
E--PVSIRPKF-
>tr|C0XM35|C0XM35_LACHI DNA topoisomerase 4 subunit A OS=Lactobacillus hilgardii DSM 20176 = ATCC 8290 GN=parC PE=3 SV=1
TDVIIPDEDVVVMVSHDGYIKRSSIRSYKASG------------ED-YPIFM-KQNARDHLFMFTSKGNLIYRPIFEIAD-----TGEHISQTI-G-DDE
E--GTFAFS-L-EKGLFLIATDDGHIKRTKLTDLA----HAYMYEKLK-KSRIVA---A--SGKLLLISKLGLAL------V--NGARTTGVKSQNLA--
-DITNLQLVNDDDVIAIVTQRGAFKKLAVK------RARKGVMIL----RLSHRV-DFTVIN-DTPLEVLTDHQRVHDILP-EFSL---YSNGSFVIDVE
E--PVKIRRKP-
>tr|A0A0A6NVD7|A0A0A6NVD7_9LACO DNA topoisomerase 4 subunit A OS=Lactobacillus curieae GN=parC PE=3 SV=1
TDVIVPDEDVIVLVSHDGYIKRSSIRSFTASS------------ED-YAIFT-EKNARDHLFMFTNKGNLIYRPVFEITD-----TGEHISQTI-G-DDE
E--ASYSFT-L-EAGCFLIATDDGYIKRVNFDDLT----HAYTYIKMK-ESRVVS---D--KKELLLTSKMGLAL------V--YGARTTGVKSMNLK--
-DVANLAIVQEDDVLGFITQRGSFKKLAVS------RARRGVNIL----RLPHRV-DFTVLK-DSPLEVITDRRKFHDIIP-DYSL---YSNGSFVVDVT
E--PVIIRQKP-
>tr|A0A0R2K1U1|A0A0R2K1U1_9LACO DNA topoisomerase IV subunit A OS=Lactobacillus parabuchneri GN=IV42_GL000441 PE=4 SV=1
TDVLVPDEDVVVMVSHDGYIKRSSIRSYKAST------------ED-YPIFM-EQNARDHLFMFTNKGNLIYRPVFEIAD-----TGEHISQTI-G-DDE
E--GTYAFN-L-ENGTFLIATDDGHIKQTGFESLT----HAYTYEKLK-DSRVVS---P--AGQLLLISKNGLAL------V--NGGRTTGVKSMGLR--
-DVTNLQLVNENSVIALVTQRGSFKKLAIK------RARKGVMIL----RLSHRV-DFCTIE-DQPLEVRTDHHRIHDILP-DYSF---YSNGSFVIDVD
E--PVSIRPKL-
>tr|S4NAT7|S4NAT7_9LACO DNA topoisomerase 4 subunit A OS=Lactobacillus otakiensis DSM 19908 = JCM 15040 GN=parC PE=3 SV=1
TDVLIPDEDVVVMVSHDGYIKRSSIRSYKAST------------ED-YPIFM-EQNARDHLFMFTNKGNLIYRPVFELAD-----TGEHISQTI-G-DDE
E--GTYAFN-L-EKGNFLIATDQGHVKQTALDDMK----HAYTYEKLK-DERVVA---P--AGQLLLISNHGLAL------V--NGGRTTGVKSIALR--
-DVANLQLVNDQSVLAIVTQRGAFKKLAIK------RARKGVMIL----RLSHRV-DFCTIE-DQPLEVRTDHRKIHDILP-DYSL---YSNGSFVIDVD
E--PVSIRPKF-
>tr|M5J696|M5J696_9LACO DNA topoisomerase 4 subunit A OS=Lactobacillus saerimneri 30a GN=parC PE=3 SV=1
TSVTVADEEVKVLISHDGYIKRSSLRSYKASD--P---------VD-YPILE-ETNTLQHLLIFTNKGNMIYRPVHELVE-----TGEHLSQTV-G-DDE
S--TAFCFA-L-QKGRFVFASKQGNIKQTDFADMK----RASKYINLK-DNEVIL---P--TKQVFIVTHAGYGL------V--SGAKAAGVKAVNLK--
-DVAGAALVQEDDQVAMVTQRGAFKRMKVT------RAIRGIKVL----RLPHKI-FMDSIT--DQVLIQTVDGANVNVIA-DYSI---HSNGSFVLDEE
Q--IATVRKLV-
>tr|A0A072NJ16|A0A072NJ16_BACAZ DNA topoisomerase 4 subunit A OS=Bacillus azotoformans MEV2011 GN=parC PE=3 SV=1
LEVLIPSEDVIVTVTKDGYIKRTSIRSYTASN--G---------ND-FLLGQ-FENTTDKLLLFTNKGNYLYLPVHEMPD-----LGQHVANIIPI-DDE
D--KAIPIR----NEFLLFFTKNGMVKRSQLSLYQ----KPLVAINLK-DEV-V----Y--SKDVFIGTHNGYGL------V--IGQRAAGVKGINLK--
-DVVSGFIFD-KPDFVLITHRGAAKRMNLK------RAKRGVVML----RLPHKT-GILSAS---TVYFKTEKDFIESLNP-DLRE---YSNGSFVIDIA
K--VKQVWKSA-
>tr|B6WBH0|B6WBH0_9FIRM DNA gyrase subunit A OS=Anaerococcus hydrogenalis DSM 7454 GN=gyrA PE=3 SV=1
IEELIEKEDVLISLTHDGYIKRLPINTYKVQNRGGKGISAGNT-ENDFIQKILTTNTHESLLCFTNLGRVYSLKCYEIPE-SRQSRGQAIINLISLSSDE
KITDIMELS-LE-KSQLVFQTENGKIKKTDAELFTNIQRNGIIAISLEDGDRLVSIRQIDKPCDIIVTTKKGMAIKFA---IRSMGRNARGVRAIRLG--
-KVVSMNIVE-EVYLVVVTANGFGKKTSFNNFNNQNRGGKGVRCHKITE-KTKDVVATLPAN-DDDIMMVSLKGDMIRISTRDIST-GRNTLGVKLKNLE
TEYIVSVTKYY-
>tr|U7UTD7|U7UTD7_9FIRM DNA gyrase subunit A OS=Peptoniphilus sp. BV3AC2 GN=gyrA PE=3 SV=1
SEDLIEEEDVVITLTEFGYIKRMPEGTYKPQRRGGTGISALTT-EEDFVKDIYITSTHDTILFFTNFGRVYSLKAYEIPES-RQAKGTAIINLLNLEGDE
FVTAVIPVR---ENANLVMATKNGLIKKTSYSEFEK-RKNGLIAITLNEGDNLIGVR-TSG-DEIMIVTKNGMAIRFSE--VRNMGRTAMGVKSIDLK--
-DVVAFEIPQ--KYLLVISENGFGKMTKMTEYRKQNRAGVGLLTYKAT-E-SGKLVSAKVIDS-DEIMIITVSGIIIRIGCEGISVMGRHTTGVKLM--N
KDEVVSVAKYI-
>tr|H3NQT7|H3NQT7_9FIRM DNA gyrase subunit A OS=Helcococcus kunzii ATCC 51366 GN=gyrA PE=3 SV=1
EEDLIEEEEVIITLTNQGYIKRLPADTYKVQNRGGRGVTGMTT-DDDFVQNLIVTSTHSTILFFTNKGKVYKKRAFEIKE-KRQSKGQAIINILQLDIDE
SISAVIAID-FE-DKYIVLATRNGKIKRMSSSEFLNIRTTGIIAITLTEGDELIAAREVQDDSKILMVTENGQSIIFE---VRPMGRTAQGVKGISLS--
-KVVDAAIID-NEYIFIVTEKGYGKKTLIKHYKAQKRSGKGVKTYKLTN-KTGKIVSTKLVN-EDQVLLVSANSEVIRLNVKDIST-GRATQGVRLKKVR
DENIVACAKYI-
>tr|A0A061NB03|A0A061NB03_9BACL DNA topoisomerase 4 subunit A OS=Geomicrobium sp. JCM 19037 GN=parC PE=3 SV=1
MQTMIPQEDVIVTVSREGYIKRTSVRSFTASN--G---------TD-DLQFF-KENTTETLLIFTEKGQYMYIPVHQIPD-----TGQHIANLANV-ADD
R--RAMPIS----DHYLLFFTKNGMAKRSLLSEYQ----RALIAIKLK-DRV-V----S--THEVMMFTQKGYGL------V--VGQRASGVKGMSLK--
-DVVSAFTFLER-HVLLMTQRGAVKRMKVS------RAKRGLTML----RLPHTV-GVYPNT--HEVMVFTDKNDMLKIAD-PTKD---YQTGSYLVDTE
N--VVDVWPYI-
>tr|A0A061NBS0|A0A061NBS0_9BACL DNA topoisomerase 4 subunit A OS=Geomicrobium sp. JCM 19055 GN=parC PE=3 SV=1
MQTMIPQEDVIVTVSREGYVKRTSVRSFTASN--D---------TD-DLTFF-KENTTETILIFTEKGQYLYVPIHQLPD-----NGQHVANLVPI-SDD
R--SVVPVE----DQFLVFITKNGMIKRTPLSEYQ----RALVALKLK-DLV-R----D--KEEVMIVTRLGYGL------A--VGQRAAGVKAIALK--
-DVTSAFTFDPK-TMLVTTQRGAMKQVKVS------RAKRGSTMV----RLPHFV-QAWPVT--NAFVARTENGDTEHVEG-SIKE---YQTGNYVVDTD
S--IEDVWPYI-
>tr|A0A075LJD4|A0A075LJD4_9BACI DNA topoisomerase 4 subunit A OS=Terribacillus aidingensis GN=parC PE=3 SV=1
LEVMVASEEVLVTVTHDGYIKRTSLRSYQASN--G---------ED-HLIGM-QENTTDKLLVFTNKGKFSFMPVHELPD-----QGQHLANIVSM-DDE
K--ASIPVR----GGYLVFFTKNGSVKRSELQLYE----KSLTAINLK-DEV-C----S--NKQLFMATNSGYGL------V--IGIRAAGVKGMQLK--
-EIVGAQAFELQ-SVVVITHRGSAKRMKLK------RAKRGVVML----RLPHRV-GFYVLE---TIHMVTKDKQDHILEP-SLNA---YSNGSYVLDTD
H--VIATYPEA-
>tr|A0A0R1T1M1|A0A0R1T1M1_9LACO DNA topoisomerase IV subunit A OS=Lactobacillus paracollinoides DSM 15502 = JCM 11969 GN=FC17_GL002900 PE=4 SV=1
TEVVVSDEDVVVMVSRDGYLKRSGVRSYSASD--P---------DD-YPIFM-DKSTLDHLYMFTNKGNLIYRPVYEISD-----TGEHISQTI-G-SDE
Q--ATYAFS-L-APGEFLIATDEGYIKRTELSALQ----RAMVYEKLK-DAHVVD---A---TTVLLMSKLGLAL------I--NGARTTGVKSMNLG--
-DVTDMQLITDDDVVSLITQRGAFKKMKAS------RARKGVMVL----HLPHEV-DFLKLQ-Q-AIEVITDHRRMHDILP-EHPL---YSNGSFVIDIE
E--PEILRLKP-
>tr|A9BGA4|A9BGA4_PETMO DNA gyrase subunit A OS=Petrotoga mobilis (strain DSM 10674 / SJ95) GN=gyrA PE=3 SV=1
EVEMIQDEDVVIVLTKWGYLKAIPSSEYKVQGRGG-G--KLK--ED-DVKEVIYTNKLSKLMLFSSAGKAYQINAYEIETL-KNTKGKHIANFISL-G-E
E--SIVAIS--DYDKDILIFTKQGKVKRTSLREFSS-R-SGIRAINLV--DVVVD---DR---DLLIVTKLGMSL------VRTMGRTAMGVNSIKLR--
-GVINVVKV-DGKKLLLITERGYGKRVSF-SYK-QNRGGIGVKTV---ISRIGPV-ATMSVE-GRDILIFTKKGKAIRVNV-NINV-GR---GVIIVRLD
D-SVVGAIEVQ-
>tr|H2J6N9|H2J6N9_MARPK DNA gyrase subunit A OS=Marinitoga piezophila (strain DSM 14283 / JCM 11233 / KA3) GN=gyrA PE=3 SV=1
ESDNIEEEDLVIVLTQWGYIKAMKSSEYKVQNRGGKGAKA--I-DNDFIIQVLQTNSLSKLLFITSKGKAFELNAYKIEKSSKDTKGKHISTYLYLENDE
KIKTIIPIE-I--NKYIMLFTKKGTVKRTALEEFSNIRRNGLKAITIKEDDTVVDALVE-EKDEVLVISAKGMSLRFRV--VRPMGRSAAGVRSIKLR--
-EVVNAVMV---KSLLLITKYGFAKRVDFKDFRLQNRGGVGLKCV--TS-RIGDIVKALAVTDESHVIVFTKLGKAIREEVSTISSLSRYAIGVRAIRLD
-EIVADAAVVI-
>tr|A0A0H2SVR6|A0A0H2SVR6_9BACT DNA gyrase subunit A OS=Marinitoga sp. 1197 GN=gyrA PE=3 SV=1
EMDNVEEEDLVIVLTQWGYIKAMKSDEYKVQNRGG-G--KIK--ND-FIIQVLQTNSLSRLLFITSKGKAFELHAYNIEKK-KETKGKHISSYL-YDD-E
K--TIIPIE--IENKYIMLFTKNGIVKRTSLKEFSN-R-NGLKAITIR--DMVID---VD---EVLVISKKGMSL------VRPMGRAASGVKSIKLRE-
-DVVNAVKVN-NKSMLLITEYGFAKRVNF-DFR-QNRGGIGLKCV---TSRIGNV-KALTVT--SHIIVFTRLGKAIREEV-TIST-SR---GVRAIRLD
E-MVADAAVVI-
>tr|A0A0C7NTV7|A0A0C7NTV7_9BACT DNA gyrase subunit A OS=Defluviitoga tunisiensis GN=gyrA PE=3 SV=1
EVDLIRDENIIIVLTKWGYIKAIPANEYKVQGRGG-G--KLK--ND-NVKELVFTNRLSKLMLISSAGKAYQINTYEVEMS-KNSKGEHIANYI-GSG-E
K--TLIPIS--YD-KDILIFTKLGKVKRTSLREFMN-R-SGIRAINIV--DTVVD---LD--KNLLVVTKKGMAL------VRRMGRDAMGVNAIKLKK-
-DVVDVVLVD-NKKLLIITERGYGKRVEF-SYR-QNRGGIGLKTV---ISKIGNV-AAMSVE--EDVLIFTEKGKAIRVNV-NITV-NR---GVIVVRLD
D-AVVDAIEVK-
>tr|A0A0Q9XTS5|A0A0Q9XTS5_9BACI DNA gyrase subunit A OS=Virgibacillus soli GN=ACA30_20725 PE=4 SV=1
LEVMIPSEDVIATVTREGYIKRTSLRSFAASN--G---------TD-RLLLQ-EENTTDTLLLFTNKGNYLFFPVHELPD-----MGQHIASLIPI-EDE
E--KVIHVK----ATNLVFVTKNGMVKKSSLASYK----RPLVAINIR-DEL-I----F--QQDLIFATHLGYVL------V--VGPRAAGVKAISLK--
-DVVGADHTSTEQAICVVTQRGAIKKMRLA------RAKRGLITL----RLPHRI-GMKIVD---ELIIRTENGKEEIISV-TLRY---YSNGSFVIDEK
D--ANLLYKKT-
>tr|A0A0K9GDP6|A0A0K9GDP6_9BACI DNA topoisomerase 4 subunit A OS=Bacillus sp. FJAT-27916 GN=parC PE=3 SV=1
LEVLIPSEDVIVTVTKEGYIKRTSLRSYTASG--G---------GD-RILHK-MDNTTDTLLLFTNKGSYIYCPVHLLPD-----AGQHISSIVPM-DDD
C--KAISVR----PGYLLFVTKNGMVKKSELGLYK----KPLVALNLK-DCV-V----H--TYTVFLATSHGYGL------V--IGARAAGVKGINLK--
-DVVSGKVFA-SSMIALVTHRGAVKKMKRS------RAKRGVVML----RLPHRV-GIEMLD---QLYIESEKGKIEEIGS-QLRP---YSNGSFFMDEA
N--IIDNWIVK-
>tr|A0A0H0YQF9|A0A0H0YQF9_LACCA DNA topoisomerase 4 subunit A OS=Lactobacillus casei GN=parC PE=3 SV=1
TTVTVADEPVMVQVSRDGYVKRSSLRSYQAVD--P---------ND-LAIFT-GERTLQHLYIVTNAGNIIYRPVYEISD-----TGEHLSQTV-G-GDE
K--AVFAFD---IAGSFVLGSSDGYIKQTALSDLQ----KPMLAMKLK-GAVVTN---T--SQDVFVVSHHAYGL------V--VGARATGVKSMDLK--
-DVVNFILVKNSAVVGILTQRGAFKRMALS------RARRGLLVL----RLPHRV-AMMAVD---RLDVLTDADKVVTLTP-QHPT---YSNGSFVIDTD
Q--PVFVRTRE-
>tr|E3BS42|E3BS42_9LACO DNA gyrase subunit A OS=Lactobacillus iners LEAF 2053A-b GN=gyrA PE=3 SV=1
DEDLIEKQNVLLTLTHNGYIKRMPADEFKVQNRGGRGIRGMGV-NDDFINHLIYVNTHDYLLFFTNKGKVYSKKSYEIPEYGRAAKGLPIINLVQL-EGE
KVQAVVKIA---TNKYLMFVTKYGIVKRISISEFTN-RRSGLIALNLRENDELSNVL-TDG-QNILIGTRLGYAVIFNE--VRTMGRVASGVRGIKLR--
-NVVGSSIVDDHSEVLVISEKGYGKRTLASEYPIKSRGCMGVKTANVT-E-NGPLVGVTVVDS-EDLMLITDAGVIIRLEVDGVSQTGRATIGVRLIKLD
G-KVASLTRVK-
>tr|A0A093UGH5|A0A093UGH5_9BACI DNA topoisomerase 4 subunit A OS=Geobacillus sp. G1w1 GN=parC PE=3 SV=1
VEALIPAEDVIVTVTKEGYVKRTSYRSYSASN--G---------TD-RLLGQ-LENTTDVLLLFTRRGYYLYCPVHTLPD-----VGQHISHLIPL-EDD
E--AAVPVS----ADQLVFVTKQGLVKRTELAQYQ----RPLVAVNVR-DEV-V----Y--RGRLWLATHGGYAL------I--VGVRAAGVKGIQLK--
-DVVAACPFPPSGCLVVVTQRGAVKKMAL-------RAKRGISVI----RVPHRV-GAVV-A---RIGLRTEKGVVEMVEA-SLRL---YGTGSFVIDID
A--VVDVWKEP-
>tr|S5ZCX1|S5ZCX1_9BACI DNA topoisomerase 4 subunit A OS=Geobacillus sp. JF8 GN=parC PE=3 SV=1
VEALISAEDVIVTVTKEGYVKRTSYRSYSASN--G---------TD-RLLAQ-LENTTDVLLLFTRRGYYLYCPVHALPD-----VGQHISSLIPL-EDD
E--AAVPVS----DRQLVFVTKQGMVKRTELSQYQ----RPLVAINLK-DEV-T----Y--RGLIWLATHDGYAL------I--VGVRAAGVKGIQLK--
-DVAAACPIRSCGSLIVVTQRGAVKKMAL-------RAKRGVRIV----RVPHRV-MAILVD---TVGIRTEKGVIETVEA-SLRL---YSTGSFVIDTD
A--VADVWKEP-
>tr|A0A0Q0YNR5|A0A0Q0YNR5_9BACI DNA gyrase subunit A OS=Geobacillus sp. Sah69 GN=AP057_11325 PE=4 SV=1
VEALIPAEDVIVTVTKEGYVKRTSYRSYSASN--G---------TD-RLLAQ-LENTTDVLLLFTRRGYYLYCPVHTLPD-----VGQHISSLIPL-EDD
E--AAVPVS----DEQLVFVTRQGMVKRTELSQYQ----RPLVAVHVK-DEV-A----Y--RGLLWLATHDGYAL------I--VGVRAAGVKGIQLK--
-DVAAACPLRPRGFLVVATQRGAVKKMAL-------RAKRGVRIV----RVPHCA-GAILVG---TVGLRTEKGATEMVET-SLRL---YATGSFVIDTD
A--VVDVWKEP-
>tr|A0A0Q0V1P8|A0A0Q0V1P8_9BACI DNA topoisomerase 4 subunit A OS=Geobacillus sp. PA-3 GN=parC PE=4 SV=1
VEALIPAEDVIVTVTKEGYVKRTSYRSYSASN--G---------TD-RLLAQ-LENTTDVLLLFTRRGYYLYCPVHTLPD-----VGQHISSLIPI-EDD
E--AVVPVS----NEQLVFVTKHGMVKRTELSQYQ----RPLVAVNLK-DQV-I----Y--RGLIWMATHDGYAL------I--VGVRAAGVKGIQLK--
-DVAAVCPICPSGSLIVVTQRGAVKKMAL-------RARRGVMIV----RVPHRV-GAVMTN---MIGMRTEKGVTETVDV-SLRL---YGTGSFLIDTD
A--VIDVWKEP-
>tr|A0A0R2LXE1|A0A0R2LXE1_9LACO DNA topoisomerase IV subunit A OS=Lactobacillus paucivorans GN=IV54_GL001953 PE=4 SV=1
TTVTVADEDVIVLVSHDGYLKRSGVRSYTASD--P---------ED-YPIFL-EKSTLNHLMMFTSKGNLIYRPVHEISD-----TGEHISQTI-G-ADE
E--ATFAFK-L-EPGRFLIATSDGYIKQTAFSDLT----RAMVFEKLK-EASVVQ---T--QTGILLLSQNGYAL------V--NGARTTGVRSMDLR--
-DVVNLALVTDKDTIAMITQRGAFKRLAMK------RARRGVLVL----HLPHRV-DFMTIP-NPPLEIITSRERTHDVMP-DHPL---YSNGSFVVDTD
E--PISLRLKP-
>tr|A0A0R2DP50|A0A0R2DP50_9LACO DNA topoisomerase IV subunit A OS=Lactobacillus senmaizukei DSM 21775 = NBRC 103853 GN=FD13_GL001756 PE=4 SV=1
TEVTVADEDVIVLVSHDGYLKRSGVRSYTASD--P---------ED-YPIFL-QKSTLSHLFMFTSKGNLIYRPVHEITD-----TGEHISQTI-G-ADE
E--ATYAFD-L-ESGRFLIATSDGYIKQTAFSDLT----RAAVYEKLK-DAQVVR---E--DRGILLVSKNGYAL------V--NGARTTGVRSMDLR--
-DVVNLALVNDSDTIALVTQRGAFKRLAMK------RARRGVIIL----RLPHRV-DFMTIP-NPALEIVTSRERTHDVLP-EHPL---YSNGSFVVDTD
E--PVSLRIKP-
>tr|A0A0R2M3M8|A0A0R2M3M8_9LACO Topoisomerase iv, subunit a OS=Lactobacillus xiangfangensis GN=IV64_GL000677 PE=4 SV=1
TEVVIPQEDVVVMISHDGYIKRTSLRSYSASD--A---------ED-FPIYL-AKNTLDHLMMFTNLGHLIYRPVYEISD-----TGEHISQTI-G-ANE
R--WVFNFA-L-ETGKFLVATNDGYVKQTAFADYV----RASQFMKLK-VSEVVT---P--TGTLVLMTQHGYGL------V--IGAKAVGVKSMDLR--
-DIVRASIANEQDLVALITQRGSFKKMKVA------RARRGVQVL----RLPHRA-DYVLLD-GVALDVLTDRGKHHSILS-DHPV---YSNGSFVVDTD
E--PVTMQLHP-
>tr|A0A0R2NG75|A0A0R2NG75_9LACO DNA topoisomerase IV subunit A OS=Lactobacillus fabifermentans DSM 21115 GN=DY78_GL001561 PE=4 SV=1
TEVVVPQEDVVVMISHDGYIKRTSLRSYTASD--T---------ED-FPIYL-AKNTLDHLMMFTNLGHLIYRPVYEITD-----TGEHISQTI-G-ANE
R--WVFDFG-L-ETGKFLVATNDGYIKQTDFADYT----RASQFIKLK-TAEVVT---P--TGTLVLVTQHGYGL------V--IGAKAVGVKSMDLR--
-DIVRATIAQDNDLIAMITQRGSFKKMKVA------RARRGVQVL----RLPHRA-DYLLID-GVALEVLTDHLKRHSILS-DHPV---YSNGSFVIDTD
E--PVAMQLHP-
>tr|A0A0R2AFA4|A0A0R2AFA4_9LACO Topoisomerase IV subunit A OS=Lactobacillus vaccinostercus DSM 20634 GN=FC26_GL002129 PE=4 SV=1
TEVLVPDEDVVVLVSHDGYIKRSSTRSYSASD--T---------DD-YPILL-AKNTLSHLFLFTNRGHLIYRPVHEIAD-----TGEHISQTI-G-ADE
R--KAMTFD-LKESGTFLMATNDGYIKQTAFKDYL----HPSTYIKLK-TSVVLN---R--NQTVLLMSYTGLAL------V--NGARTAGVKSMNLR--
-DVVNMALCDEGDNIALITTRGAYKEMKLE------RARKGVLIL----RLPHRA-DFIDYP-EGALEIITDRPIIQDVLT-DHPL---YSNGSFVLDTD
Q--PISLRRKL-
>tr|A0A0D1ABH8|A0A0D1ABH8_9LACO DNA topoisomerase 4 subunit A OS=Lactobacillus wasatchensis GN=parC PE=3 SV=1
TKVLVPDEDVIVLVSHDGYIKRSSIRSYNASG--S---------DD-YPILL-TKSTLSHLFLFTNKGHLIYRPVHELTD-----TGEHISQSI-G-DDE
Q--KALTFD-L-EAGNFLVATDDGYIKQTAFKDYL----HPSIYIKLK-QSRVVN---A--LGTVLLMSVNGLAL------V--NGARTAGVKSMGLR--
-DVVNVALVQEKDNVAIVTSRGAFKEIKVA------RARKGVLIL----RLPHRA-DFINYP-AGAFEIITDRPITQEVLA-DHPL---YSNGSFVLDVD
Q--PVTLRAKS-
>tr|A0A0A1GXL9|A0A0A1GXL9_9LACO DNA topoisomerase 4 subunit A OS=Lactobacillus hokkaidonensis GN=parC PE=3 SV=1
TKVLVPDEDVVVLVSHDGYIKRSSVRSYNASG--G---------DD-YPIML-TKSTLSHLFLFTNKGHLIYRPVHELAD-----TGEHISQSI-G-DDE
Q--KGLTFD-L-DTGNFLMATNDGYIKQTAFKDYL----HPSTYIKLK-DSRVVN---T--G-TVLLMSVNGLAL------V--NGARTAGVKSMGLR--
-DVVNVTLVAETDNVAIVTSRGAFKEIKMA------RARKGILIL----HLPHRA-DFINYP-AGAFEIITDRPIIQEVLV-DHPL---YSNGSFVLDVD
Q--PVVIRAKA-
>tr|A0A0R1REK1|A0A0R1REK1_9LACO Topoisomerase IV subunit A OS=Lactobacillus oligofermentans DSM 15707 = LMG 22743 GN=FC70_GL001648 PE=4 SV=1
TKVLVPDEDVIVMVSKDGYIKRSSVRSFTATG--E---------DD-YPILL-EKNTLSHLFLFTNKGHLIYRPVYEISD-----TGEHISQSI-G-DDE
N--EAMTFK-L-ESGQFIVATDDGYIKQTMFKDYL----HPSVYIKLK-DARVTS---S--NETVLLMSYNGLAL------V--NGARTSGVKSMGLK--
-DVVNMQIVKDNDNVAIITTRGAFKAMKLE------RARKGVLIL----RLPHRA-DFIAYE-KGAFDIITNRPTVQEVLS-EHGL---YSNGSFILDVE
Q--PVTIRQKS-
>tr|A0A0R1V257|A0A0R1V257_LACPN DNA topoisomerase IV subunit A OS=Lactobacillus plantarum subsp. argentoratensis DSM 16365 GN=FD10_GL002127 PE=4 SV=1
TEVVIPQEDVIVMISHDGYIKRTSLRSYSASE--P---------ED-YPIYL-AKSTLDHLMMFTNMGHLIYRPIYEIAD-----TGEHISQTI-G-ANE
R--WVYSFE-L-ATGKFLVATSDGYIKQTAFADYT----RASQFIKMK-DATVVT---P--TGTLILITQHGYGL------V--IGAKAVGVKSMDLR--
-DIVRATIAADNDLIAMITQRGSFKKMKVA------RARRGVQVL----RLPHRA-DYVLVA-GVALDVLTDRGRHHSILN-DHPI---YSNGSFVVDTD
E--PVSMQIHP-
>tr|A0A0R1M2F7|A0A0R1M2F7_9LACO DNA topoisomerase IV subunit A OS=Lactobacillus odoratitofui DSM 19909 = JCM 15043 GN=FD04_GL001065 PE=4 SV=1
TEVMVPDEEVVVMVSHDGYLKRSGIRSYNASD--P---------ED-YPIFT-EKSTLNHLYMFTNLGNLIYRPVHEITD-----TGEHISQTI-G-ANE
E--ATYAFE-L-EAGEFLITTSDGYIKRTSFDSLL----RAMVFEKLK-DAQVVN---A---ASILLMSRLGQGL------V--NGARTTGVRSMNLG--
-DVVNMQLVNDDDVVALITQRGAFKKMSAS------RARKGVQIL----HLPHEV-DFIKLT-EAPLEVITDRCKVHDILP-EHPL---YSNGSFVIDTE
E--PESLRQKP-
>tr|A0A0R1QYM4|A0A0R1QYM4_9LACO DNA topoisomerase IV subunit A OS=Lactobacillus spicheri DSM 15429 GN=FD37_GL000905 PE=4 SV=1
TEVTVADEEVIVLVSHDGYLKRSGVRSYTASD--P---------ED-YPIFL-KQSTLDHLMMFTSKGNLIYRPVHEISD-----TGEHISQTI-G-ADE
E--ATYAFK-L-EPGHFLIATSDGYIKQTAFSDLT----RAATFEKLK-DARVVA---T--DAGILLISKNGYAL------V--NGARTTGVRSMDLR--
-DVVNLALVTDKDTIGLVTQRGAFKRLAMK------RARRGVIVL----RLPHRV-DFLVIP-NPALEVITSRERTHDILP-EHPL---YSNGSFVVDTD
E--PTQLRLKP-
>tr|A0A0R1K432|A0A0R1K432_9LACO DNA topoisomerase IV subunit A OS=Lactobacillus namurensis DSM 19117 GN=FD30_GL000058 PE=4 SV=1
TEVTVPDEDVVVMVSHDGYLKRSGIRSYTASD--P---------ED-YPIFM-EKSTLDHLMMFTSKGNLIYRPVHEIAD-----TGEHISQTI-G-ADE
E--ATFAFK-L-EPGHFLIATSDGYIKQTAFADLT----RAAMYEKLK-EVRVVA---K--DQGILLVSRDGYAL------V--NGARTTGSRSMNLH--
-DVVNLALVTDHDTIALVTQRGAFKRLAMK------RARRGVMVL----RLPHRV-DFLTIP-NPALEVITDRMRTHDILP-EHPL---YSNGSFVVDTD
E--PVQLRLKP-
>tr|A0A0R1LP64|A0A0R1LP64_9LACO DNA topoisomerase IV subunit A OS=Lactobacillus acidifarinae DSM 19394 GN=FD25_GL000579 PE=4 SV=1
TEVTVADEEVVVMVSHDGYLKRSSIRSYTASD--A---------ED-YPIFM-EKSTLAHLMMFTNKGNLIYRPVHEIAD-----TGEHISQAI-G-ADE
E--ATFAFK-L-EPGHFLIATSDGYIKQTAFETLT----RAAVYEKLK-DARVVA---D--ERGVLLVSKNGYAL------V--NGARTTGVRAMDLR--
-DVVNLALVTDRDTIALITQRGAFKRLAMK------RARRGVLIL----HLPHRV-DFLVIP-NPALEIITSRERTHDVLP-EHPL---YSNGSFVVDTD
E--PVQLRLKP-
>tr|A0A0R1I210|A0A0R1I210_9LACO DNA topoisomerase IV subunit A OS=Lactobacillus kimchicus JCM 15530 GN=FC96_GL000275 PE=4 SV=1
KEVVVADEDVVVLVSHDGYLKRSAVRSYSASD--P---------DD-YPIFT-ERSTRDHLLMFTNKGNLIYRPVHEITD-----TGEHISQTI-G-ADE
M--ATYAFK-L-VPGEFLIATDDGYVKRTSVKDLH----RAMVYEKLK-SASVVN---P--GSTVLLMSKQGLAL------I--NGARTTGVKSMNLG--
-DVVDLHLVQESSEVALITQRGAFKKMAAS------RARKGVLIL----HLPHTV-DFLTLS-TDPIEIVTDHRRHHDVLP-DYPL---YSNGTFVVDTD
E--PVTMRIKP-
>tr|A0A0R2AZS5|A0A0R2AZS5_9LACO DNA topoisomerase IV subunit A OS=Lactobacillus brantae DSM 23927 GN=FC34_GL000340 PE=4 SV=1
TTVTVTDEQVMVLVSRDGYVKRSSLRSFQAVA--P---------ND-FVVFS-EESTLTHLYIATNKGHLIYRPVYEISD-----SGEHLSQTV-G-ADE
K--AAFDFD-L-GDGRFVFGSSDGYIKQTALADLQ----KPMVAMKLK-DANVTN---A--NTNVVAVSNQAYGL------V--VGARTTGVKLMDLK--
-DVVNFVLVADAAKIAILTQRGAFKQMAVS------RARRGLMVL----RLPHRV-AMALI--NQSLAVLTDQDTSITLNP-EHPS---YSNGSFVIDTE
Q--PVLMLPVI-
>tr|A0A0R2MX98|A0A0R2MX98_9LACO DNA topoisomerase IV subunit A OS=Lactobacillus saniviri JCM 17471 = DSM 24301 GN=IV56_GL001386 PE=4 SV=1
TAVTVTDEQVMVLVSRSGYVKRSSLRSYQAVA--P---------ND-FAVFS-GEGTLQHLYIVTSAGHMIYRPVHEISD-----SGEHLSQTV-G-GDE
Y--AVFTFD-L-ASGNFVLGSSDGYIKQTALADLQ----KPMVAMKLK-DAIVTN---D--DQNVVAVTNQAYGL------V--VGARTTGVKLVDLK--
-DVVGFILD--VDTIGLLTQRGAFKRMHVS------RARRGLMVL----RLPHRV-ALTPV--NGLITIFTDQDQQIELDP-AYPN---YSNGSFVFDPE
Q--LAYVEVQD-
>tr|I6T0Z1|I6T0Z1_ENTHA DNA topoisomerase 4 subunit A OS=Enterococcus hirae (strain ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 645
TKVLVAQEDVIVSVTKEGYVKRTSLRSYSASK--P---------GD-YLLYS-GENTLDHVLLITNKANVIYRPVHELPD-----AGEHISQTIVN-SDE
S--AVFPYK----EKTLVFISKNGWVKQTRMTEFE----RPLSGMKLK-DDELVA---E--DLDLFLVTYQGMGL------V--VGAKAAGVRSINLKE-
-TVVNGLLVLTDTPIIIVTQRGAVKRMLAQ------RAKRGVTVL----RLPHRI-HMSEGN---EIMIINQKGQELMIDP-DYPI---TSNGSFAVDEK
G--VIKVIEPP-
>tr|E6LFL0|E6LFL0_9ENTE DNA topoisomerase 4 subunit A OS=Enterococcus italicus DSM 15952 GN=parC PE=3 SV=1
TEILVAQEDVMVVVTREGYVKRSSLRSYSASN--N---------SD-VVVYK-GQNTLDHLLLVTDKGNMIYRPVHELPD-----VGEHLSQALTT-KEE
N--TVLPYK----TQELLILTQAGMIKRTKLSEFT----RPLPFITLK-EDKVIS---E--TQDIFMVSNRAYGL------V--VGPRAAGVKAMNLKD-
-AVVQAILVHTDTPVVIITQRGAAKRMLAQ------RAQRGIMVL----RLPHRI-YMGLGD---ELLLTNQKGDKKEVQA-QFPI---TSNGSFVLDEK
G--IVSVDELP-
>tr|S0L7P5|S0L7P5_9ENTE DNA topoisomerase 4 subunit A OS=Enterococcus sulfureus ATCC 49903 GN=parC PE=3 SV=1
TEVLVAQEDVMVTITHEGYMKRSSLRSYSASN--G---------GD-YVVYQ-AQNTLDHLLLVTNKGNVIYRPVHELPE-----VGEHISQMITN-EEE
T--QVFAYR----NATFVLFTKDGYTKQTLQTEFS----RSQTMIKFK-ADELIG---Q--TLDAYLTTHQAFAL------I--LGAKAAGVKSVNLKE-
-YVVGASLIDPQTPVTYVTQRGALKRMIAQ------RAQRGLMVF----RLAHRV-GMALGE---GLQVINQKGDQLEVMA-HYPI---QSNGSFILNEK
G--VTQVHIHE-
>tr|A0A0R2NKP2|A0A0R2NKP2_9LACO DNA topoisomerase IV subunit A OS=Pediococcus argentinicus GN=IV88_GL000097 PE=4 SV=1
RTVTVPEEQVMVLVSHDGYLKRSSLRSYTASG--D---------ED-YPIYQ-HENTLDHLFMFTNKGNLIYRPVHEITE-----TGEHISQTI-G-ADE
V--QTFAFK-I-ETTNFLICTNNGYIKRTSLLDLK----KAATYIKLK-EAFVTH---P--KYTIMLASKNGYGL------I--VGARAAGVKAMDLR--
-DIVDFVLVQDNDQVGFITNRGAFKKMAVS------RARRGVLIL----RLPHRM-GFAKLV-DRALEVITDRGQIHDVIP-DHPL---YSNGSFLIDVD
E--PTSLRLKP-
>tr|A0A0R2L033|A0A0R2L033_9LACO DNA topoisomerase IV subunit A OS=Pediococcus stilesii GN=IV81_GL000049 PE=4 SV=1
RTITVPEEQVMVLVSQSGYLKRSSLRSYKASF--E---------GD-FAVFK-KESTLDHLLMFTNKGNLIYRPVHEISE-----TGEHISQTI-G-DDE
I--EAYNVK-F-QPIAFLIATSDGYIKQTALADFK----KATMFIKLK-AATVVK---S--RGTIFLASHNGYGL------I--VGARAAGVKSMDLR--
-DVVNFVLVDEDDQIGIITNRGSFKKMRVK------RARRGVQIL----RLPHRI-DIAVVE-GQALEVLTSRGMFHDIIP-DHPL---YSNGSFIIDTD
E--PISMREKE-
>tr|A0A0R2ELT5|A0A0R2ELT5_PEDAC DNA topoisomerase IV, A subunit OS=Pediococcus acidilactici GN=IV78_GL000359 PE=4 SV=1
RTVTVPEEQVMVLVSQAGYLKRSSLRSYKASA--D---------GD-QPVFK-HESTLDHLLMFTNKGNLIYRPVYEITE-----TGEHVSQTI-G-ADE
I--KAYDVK-F-QPINFLIATDDGYIKQTALQDLK----KAITYAKLK-GAKVVN---D--PATILLASEHGYGL------I--VGPRAAGVKSMDLR--
-DVANFVLVNDEDQIGLITNRGSFKRMKVS------RARRGVQIL----RLPHRV-DIAVVN-HQAFEVLTSRGLVHDILP-EHPL---YSNGSFVIDID
E--PLSMRLKT-
>tr|Q03FK8|Q03FK8_PEDPA DNA topoisomerase 4 subunit A OS=Pediococcus pentosaceus (strain ATCC 25745 / 183-1w) GN=parC PE=3 SV=1
RTITVPEEQVMVLVSQSGYLKRSSLRSYKASA--E---------GD-FTVFK-KENTLDHLIMLTNKGNLIYRPVHEIME-----TGEHISQAI-G-ADE
I--KAFDVK-F-EPVSFLIATSDGYIKRTSLKDFK----KAAVYIKLK-DAKVVN---T--KETILLATRNGYGL------V--VGPRAAGVKSMDLR--
-DIANFVLVNDHDQIGLITNRGSFKKMKVS------RARRGVQIL----RLPHRA-DIEVVE-GEAFEVRTSRGLIHDIIP-EHPL---YSNGSFLVDVD
E--PVSMNLKE-
>tr|F4EF51|F4EF51_STRSU DNA topoisomerase 4 subunit A OS=Streptococcus suis ST3 GN=parC PE=3 SV=1
TASLIVEEETFVSVTKAGYIKRTSPRSFNAST--L---------DD-QLIFL-QNKTTQHLLLFTNLGNVIYRPVHELTD-----IGEHLSQTLMN-DSE
E--FAELVE----GT-YFAVTQYGQIKRVERKEFT----KSTKYAKLK-EDVVIT---V---DDIMLMTEKGYAL------V--IGAKAAGVKAVNLK--
-DVVAAFISNT-SSVYLLTQRGSFKRMATE------RAKRGLQVL----RLPHRF-AAGPVLDSQILHVQSKTGKLYEVDV-QLSL---TSNGSFISDTI
D--VFRAWID--
>tr|A0A0R1QF46|A0A0R1QF46_9LACO Dna topoisomerase iv subunit a OS=Lactobacillus manihotivorans DSM 13343 = JCM 12514 GN=FD01_GL001686 PE=4 SV=1
TTVTVADERVMVLVSRDGYMKRSSLRSYQAVD--A---------KD-FPIFD-QEGTLQHLYIITNHGNVIYRPVHEITD-----AGEHLSQTV-G-DDE
Q--AAFGFD-L-QAGNFVLGSSDGYIKQTALADMQ----RPMVGMKLK-DAVVTN---E--KQTVFAVTNQAYGL------V--IGARATGVKSIDLK--
-DVVNFILADDSTEVGILTQRGAFKKMKLK------RARRGLMVL----RLPHRV-AMNVV--NTTLTVLTDNDTLVPLDP-ASPD---YSNGSFVIDTE
Q--PTYVHAET-
>tr|A0A0R1JPS7|A0A0R1JPS7_9LACO DNA topoisomerase IV subunit A OS=Lactobacillus nasuensis JCM 17158 GN=FD02_GL001184 PE=4 SV=1
TAVTVTDERVMVLVSRDGYVKRASLRSYQAVD--P---------TD-LPIFV-QEGTLQHLYIFTNLGNVIYRQVHEIAD-----AGEHLSQTV-G-GAE
Q--AVFGFD-L-AAGNFVLGSSDGYIKQTSLADLQ----KAMVGMKLK-GAIVTN---P--DRSVFMVTRNGYAA------V--IGARATGVRSMALK--
-DVVNFIIVTDTTEVAILTQRGAMKRMALS------RARRGLLVL----HLPHRV-AMTAM--TSQLLVLTDSGTQKLLEP-SLTP---YSNGSFLIDTD
E--PVAMYPQP-
>tr|A0A0R2FN22|A0A0R2FN22_9LACO DNA topoisomerase IV subunit A OS=Lactobacillus camelliae DSM 22697 = JCM 13995 GN=FC75_GL000119 PE=4 SV=1
TAVTVTDERVMVLVSRDGYMKRSSLRSYQAVA--A---------ND-FPVFE-REGTLQHLYIFTSAGNVIYRPVHELED-----AGEHLSQAV-G-GDE
H--AAFGFD---AKGNFVLGSSDGYIKQTALADLQ----RPMVGMKLK-DAYVTD---Q--KQTVFAVTNQAYAQ------V--IGARSTGVKSMALK--
-DVVNFILAD-QTEVGILTQRGAFKKMKLK------RARRGLMVL----RLPHRV-AMSKVD-NTLITVVTDKDQQVELTV-NYPD---YSNGSFVLDTD
V--PSFIHLSQ-
>tr|A0A0R1SFK3|A0A0R1SFK3_9LACO DNA topoisomerase IV subunit A OS=Lactobacillus versmoldensis DSM 14857 = KCTC 3814 GN=FC27_GL000756 PE=4 SV=1
TKVMVASEEVRVLVSHDGYVKRSSQRSYMASE--P---------ED-YPILD-VENTLDHIFIFTDKGNLVYRQIYELED-----TGSHLSQEV-G-ADE
S--KAFIFK---QTGTFITGTNGNYIKQVSFEDLL----RAARYIKLK-QTRVLD---A--DDLVYVFTKHSYAS------V--VGSKAVGVKFVSLK--
-DVVSYFIADQTDKIALLTQRGSYKQMKLA------RARRGVLTL----RLPHRQ-LIAK-T-DTELHVITDQNSDIAIDF-AHND---YSNGSFILDPE
D--PLRFQKIY-
>tr|A0A0H4QIX6|A0A0H4QIX6_9LACO DNA topoisomerase 4 subunit A OS=Lactobacillus ginsenosidimutans GN=parC PE=3 SV=1
TKVMVASEDVHVLVSHDGYVKRSSQRSFAASD--P---------ED-YPILD-VENTLNHLFIFTDKGNLIYRQIFELED-----TGSHLSQEV-G-GDE
S--KAFIFE---QTGTFLTGTNGNYVKQIDFQDLL----RASRFIKLK-DTTVLD---S--NKLVYVFTEHSYAS------V--VGSKAVGVKFVSLK--
-DIAGYFIADKSDKIAILTQRGSYKQMKLS------RARRGVLTL----RLPHRL-LVTKTN---ELHVITDQNNDISIDF-AHND---YSNGSFILDPS
D--PIRFEIIN-
>sp|D5ECW5|GYRA_AMICL DNA gyrase subunit A OS=Aminobacterium colombiense (strain DSM 12261 / ALA-1) GN=gyrA PE=3 SV=1
IEDLIPESDIVVVLSRDGYLRRKDLQEYTLQGRGGKGRKGTAL-EEDEVALVAVTSTHRDIYLFTSKGRVLALKGYVIPE-SKTGRGKLINRFVALEEGE
RVVTMHGRA-VDGAKYAFFITLRGTAKRLDLSELENLTRAGRRVMGLDEGDEISQIVLTSGDDHLLIVTAQGQALRTHE--FRPMGRTARGVRGIRLR--
-YVIGCDVVAN-RWPLLLSENGFGKRTKYDEFSLRHRGGSGVIVM--SD-RTGLIVGCWSVAEGDEIVAITSRGRMIRLAVSESPVLGRTAMGSIMMRLD
-GTVATASVVS-
>tr|D3L3I6|D3L3I6_9BACT DNA gyrase subunit A OS=Anaerobaculum hydrogeniformans ATCC BAA-1850 GN=gyrA PE=3 SV=1
DDELIPEEDIVVVLSKDGYLRRASLGDYHLQGRGGKGIKGLKQ--DDEVEMFAATTTHHDIFLFTSKGRVFAIKGYLLPE-PKNGKGKHVSSFFTLEENE
RVVAIKEDT-MHGARFVFFATERGIAKRLDVSELANLTRAGRRVITLDDGDFIARVRFTSGEDELLFVSAKGQALRTSE--FRPMGRQARGVRAIRLS--
-VLVGCEPLQE-MAILFISEKGVGKRTSFDEFPLHHRGGSGVRAM--SS-RTGSLVGAWSVTEDDEVMIVTSKGRVTRIAVRNVPVLSRTATGSILVRLD
-GSVADITIVR-
>tr|I4BU81|I4BU81_ANAMD DNA gyrase subunit A OS=Anaerobaculum mobile (strain ATCC BAA-54 / DSM 13181 / NGA) GN=gyrA PE=3 SV=1
EDELIPEEDIVVVLTKDGYLRRAPLGDYRLQARGGKGIKGFNP-NEDEVAMFAATTTHHDIFLFTNKGRVFAIKGYLLPE-PKNGKGKHVSSFFTLEEGE
RVVAIKDDT-MHGAKFVLFATKNGIAKRVDVRELGNLTRAGRRIINLDEGDEIARVRFTSGSDDLLFVSAKGQALRTSE--FRPMGRQARGVRAIRLS--
-ILVGCEPLRE-TMILLISEKGVGKRTSSDEFPLHHRGGSGVRAM--SG-RTGLIVGAWSVTEDDELMIVTSKGRVTRITVKDVPVLSRTATGNILVRLD
-GEVADVTVIR-
>tr|D2Z564|D2Z564_9BACT DNA gyrase subunit A OS=Dethiosulfovibrio peptidovorans DSM 11002 GN=gyrA PE=3 SV=1
DEDLIPREDIVVMLSRDGYLRRVPLEDYSLQAKGGKGRRGARL-EEDEVSLMGVSTTHDDIFLFTTKGRVFAIKGYIIS-ESRTGKGKLIGKYISLENDE
RVVSMK-TR---ESGFLFFLTRRGIAKRLPSSELDNLTRAGRRVVTLDEGDEIAQILPTSGMDDLLLVSAMGQALRVSE--FRPMGRSARGVKAMRLK--
-RIISGEVVTE--RPILVSETGIGKRTNFEDFTVHHRGGGGMKVM--NS-RTGLLAAATSVSEDDEIIVMTAKGRMIRVAAKEIRVLGRTAAGSIVVRLD
-GSVVDLSVVN-
>tr|G7V794|G7V794_THELD DNA gyrase subunit A OS=Thermovirga lienii (strain ATCC BAA-1197 / DSM 17291 / Cas60314) GN=gyrA PE=3 SV=1
FEDLIPEEEIVVILSRDGYIKRMPLQTYRCQGRGGKGVKGATP-SGDEAAIITVSSTHRDIFLFTSRGRVYAIKGHVLPE-PKVGKGRLVSNYINLDANE
SIVAVADSK-LKGAKYVFFITEKGTAKRMPAEELVNLTRAGRIVLSLGEGDKIARVRFTSGEDELLFVTAHGKALRVKE--FRPMGRQAKGVRGIRLA--
-IVVGCDVIKE-KQTFLVSAKGVGKRTEYSEFTCHHRGSGGVKAM--SD-KTGLLVGSWSLAPEDEVMLMTSMGRVIRLDAKDISILSRVATGYRVVKLE
-GEVADVSVIH-
>tr|H0UPS6|H0UPS6_9BACT DNA gyrase subunit A OS=Thermanaerovibrio velox DSM 12556 GN=gyrA PE=3 SV=1
AEDLIPETEIVVAMTRDGFIRRMPLQDYRCQSRGGKGVKGAST-GDDEVSLVAVTTTHRTLYLFTDRGRVFALKCLALPE-PKSGRGKHVGSFISLDEGE
SVVTFRDSV-MERAKFVFLLTRMGLAKRLPVAELEGITRAGRRILGLEDGDTIARVRFTGGDDELLLTTAKGQTLRVSE--FRPQGRAAKGVKAIKLE--
-AVVGCDVIIP-RQVLFISQLGLGKRTPYEEFTTHHRGGMGVRAM--ND-KTGDLVGAWGVAEDDELMVVTSRGRVIRMAAREISTLSRMATGSTVVRLD
-GSVADVTVIR-
>tr|E3CZ44|E3CZ44_9BACT DNA gyrase subunit A OS=Aminomonas paucivorans DSM 12260 GN=gyrA PE=3 SV=1
AEDLIPESEIVVVLSRDGFLRRMPLQDYRCQSRGGKGVKGAST-GEDEIALVTVTTTHRTLYLFTSRGRVFAIRGFTLPE-PKTGKGKHVSTFVSLEEGE
RVVTLRDSR-LDGARFVFFVTQRGVAKRLPVTELDGINRAGRRILGLAPEDTIARVRFTGGEDELLLTTAQGQTLRVPE--FRPQGRTAHGVRGVRLD--
-LVVGCDVIEP-RQVLFISERGIGKRTPYDEFTAHHRGGGGVRAM--VD-RTGDLVGAWGVREDDELVVISAKGRMVRLLAGEISSLGRAATGYKVVRLD
-GEVADVSIIR-
>tr|D1B8A6|D1B8A6_THEAS DNA gyrase subunit A OS=Thermanaerovibrio acidaminovorans (strain ATCC 49978 / DSM 6589 / Su883) GN=gyrA PE=3 SV=1
YEDLIPETEVVVAMTRDGFIRRMPLQDYRCQARGGKGVKGAAV-GEDEVSLVAVTTTHRSLYLFTDRGRVFSLKCLAIPE-PKSGRGKHVSTFISLDEGE
SVVTFRDSA-LEGARFVFLVTKMGLAKRLPVGELEGITRAGRRILGLEEDDTIARVRFTGGEDQLLLTTAKGQTLRVSE--FRPQGRAAKGVRGIKLD--
-LVVGCDVIMP-RQVLFISQLGMGKRTRYEEFTVHHRGGMGVRAM--GE-RTGHLVGAWGVADDDEIMVITSRGRVVRFSARDVSSLSRSAMGLTLVRLD
-GQVADVTVIR-
>tr|A0A0R2G705|A0A0R2G705_9LACO ParC protein OS=Lactobacillus selangorensis GN=IV38_GL000350 PE=4 SV=1
TSVMVADDDVMVMVSHDGYLKRSSMRSFQASA------------VD-YPVLQ-VKHTLAHLYIFTNYGHMIYRPVHEILD-----AGEHLSQTV-G-ADE
S--AAYIFE---QTGQFVMASTDGYIKQTSFADLK----HPQQAIKLH-HVRLAD---A--DLQVVSASHKGYGL------V--MGARTRGVKLMDLK--
-DIVDFVLVSP--EVGIITQRGAFKKMNVT------RARRGVQIL----RLPHRA-AMTLVT-ATTLMVETDQQQFFAIDP-QYPS---YSNGSFVLDPD
I--PSGVHLKR-
>tr|V7PW94|V7PW94_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium RAAC4_OD1_1 GN=gyrA PE=3 SV=1
EEDLIPEKESVLVFTKGGYVKRTDPSEYKAQKRGG-G--IIE--ED-FVTMLISANTHSDLLFFTNLGKAYQIKMYDIPEK-RATKGKSIMNFI-SDE-E
K--TILPID--KTVESLMLVTKMGVAKKVEALGFKD-R-SGLIAIKLD--DELEN---I---DDVMLATTLGQSI------VREMGRTAGGVRAIKLGG-
-FVIGVDRVPRDLSLLTLGSNGLGKKTNI-EYK-QKRSGSGIKTA---TAKTGKI-VAKIV---NEIIAVSQKGQVIRVDL-SIPT-GR---GVTIMKLR
G-SIASITCL--
>tr|A0A0G1BBV0|A0A0G1BBV0_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWA2_42_18 GN=gyrA PE=3 SV=1
DEDLVPEKESVLVFSAGGYVKRTDPTEYRRQKRGG-G--ILE--ED-FVTILLSANTHSDLLFFTNLGKVFQMKMYDLPER-RATRGKSIMNFL-QGD-E
K--SILPMP--SSVPPLLMVTKNGTAKKTAGDGFRD-R-SGLIAIKLT--DELQS---V---DEVIMATTKGQSI------IRLMGRTAGGVRAMKIDG-
-SVIGVDTIKSDGFFLTMSQNGLGKKTTL-EYK-QKRGGSGIKTA---TPKTGDI-VGRVI---EELIAMSKKGQVVRVQL-SVPA-RR---GVTIMKMR
G-GIASLTCL--
>tr|J4UJV1|J4UJV1_STRAP DNA topoisomerase 4 subunit A OS=Streptococcus anginosus SK1138 GN=parC PE=3 SV=1
TASLIVEEETYVSVTRGGYLKRTSPRSFNSST--V---------DD-RLIFI-SSKTTQHLLIFTNLGNVIYRPVHELAD-----IGEHLSQTITN-ENE
E--YTELVD----GT-YFAVTKLGQIKRVERKEFS----KSVKFAKLK-DDQIIT---K---DDVMLVTKNGYAL------V--VGAKAAGVKAINLK--
-DLAAAFIANT-DSLYILTQRGALKRMAVA------RANRGLQVL----RLPHRF-QAGPVFTEQILSIVSNKGTTYQVNL-DLGL---TSNGSFISDTI
D--VFSANLK--
>tr|A0A0N9NAG5|A0A0N9NAG5_9EURY DNA gyrase subunit A OS=Halanaeroarchaeum sulfurireducens GN=gyrA PE=4 SV=1
DEDLIPNEEVVVSLSEQDYIKRVPVETYSAHNRGGKGIIGADL-EGDRIATVFTARTHDHLLCFTDQGQVYRLKVYQIPEMSRTARGTSAVNLL-DDDEE
EITAVVATD---EDEYLTMATRNGYVKRTGAEEFENILSTGIIAISLADGDELVDVE-TNGASDVVLGTEKGMAIRFDE--VRSMGRNARGVWGIELE--
-DVAGVSAIREDRTLLTVTRRGFGKRTPLSEYRRQSRNGKGLVDI--DR--NGWVAAIEAVAETDHVIAMSDDGQIIRMPVAEISTVGRNTKGVRVMAID
-DQLAGISVFP-
>tr|A0A0R2GJ14|A0A0R2GJ14_9LACO DNA topoisomerase IV subunit A OS=Lactobacillus homohiochii GN=IV51_GL000388 PE=4 SV=1
EEVTLPDENVMVLVSNDGYLKRSSLRSFNASE--I---------DD-HAVYL-NENTHDSLFMFTDKGNMIYRRVYEVED-----TGEHISRMN-G-DNE
K--DVYAFP-L-QDGEFVITTSGGHIKRTEFSKLL----RAAVYEKLK-LSRVVD---R---GSVLLMTEMGLAL------V--SGPRTTGVKAISLD--
-DVINMQFVDDNSEIALIFQNGNFKKMKVS------RARKGIKVL----KFSNLA-DFIKIE-DETLKVYTDHMTSHDVIL-DHGI---LSNGSPVMDTK
I--PIMITHDA-
>tr|A0A0A1MXH9|A0A0A1MXH9_9BACI DNA topoisomerase 4 subunit A OS=Oceanobacillus oncorhynchi GN=parC PE=3 SV=1
IEVTVASEDVLVSVTRDGYVKRTSLRSYAASN--S---------DD-HPISL-LENTTDNIMLFTNKGRYIICSVHELPD-----MGQHISHIVPL-EEE
H--KVIPVR---EDGFLMFFTRNGMVKRSEFQLYE----KALIALNLK-DEL-V----S--GKDIFIATNKGYGL------V--VGQRAAGVKSISLK--
-DVVNGQVFDLK-DLFIITQRGASKRMKLK------RAKRGLLML----KLPHRQ-GFFMVN-QEMICYKTKNGDTQKVYP-ELSA---YGNGSFMIDAD
T--VMEVYKET-
>tr|A0A024QBM7|A0A024QBM7_9BACI DNA topoisomerase 4 subunit A OS=Virgibacillus sp. Vm-5 GN=parC PE=3 SV=1
IEVMVASEDVLLSVTRDGYIKRTSLRSYSASN--G---------DD-HLVRL-IENTTDKILLFTNKGKYIYLPVHELPD-----IGQHISNIVSI-ENE
R--ECIPVR----ENYLLFFTKNGMVKRSQLKLYD----KALIALNLK-DEV-V----H--YSDVFIASDKGYGL------I--VGQRAAGVKAIQLK--
-EVVNGQVFDDEPSLVVLTQRGACKRMKLQ------RAKRGVVML----RLAHRR-GFFLAN---TINFQTKNGEIHHVYP-ELSN---YSNGSFIVDTD
Q--VIQVWKHA-
>tr|A0A075JNR4|A0A075JNR4_9BACI DNA topoisomerase 4 subunit A OS=Virgibacillus sp. SK37 GN=parC PE=3 SV=1
IEVMVASEDVLVSTTRDGYIKRTSLRSYAASN--G---------ED-HLVGL-IENTTDKILLFTNKGKYLSIPVHELPD-----IGQHISNIASI-DDE
R--QCLPVR----DNYLIFFTKNGMVKRSELPLYD----KALIALNVR-DEV-V----C--HADIFVASDKGYGL------I--VGQRAAGVKAIQLR--
-EVISGQVFDDEPSLVLITQRGACKRMNLK------RAKRGLVML----RLPHLV-GLFVVD---SLCFQTESGEKHTVFP-ELPL---YSNGSFVIDTD
H--VREVWKKA-
>tr|Q8EQK4|Q8EQK4_OCEIH DNA topoisomerase 4 subunit A OS=Oceanobacillus iheyensis (strain DSM 14371 / JCM 11309 / KCTC 3954 / HTE831) GN=grlA PE=3 SV=1
IEVTVASEDVLVSVTRDGYLKRTSLRSYAASN--E---------DD-YPISL-LENTTDNLLLFTNKGKYILCPVHELPD-----MGQHISNIVPL-DEE
Y--QCMPVR---AEGYLIFFTKNGMVKRSEFQLYD----KALIALNLK-DEV-V----S--NMDVFIATYKGYGL------I--VGQRAAGVKSVSLK--
-DVVNGQVFDDP-SLALITQRGSCKRMKLK------RAKRGVIML----RLAHRK-GFFALQ-GQQICFQTANGNTHEIVP-TLKA---YNNGSFVIDTD
E--VIHVWKQA-
>tr|A0A0N1EUR3|A0A0N1EUR3_9BACI DNA topoisomerase 4 subunit A OS=Oceanobacillus caeni GN=parC PE=3 SV=1
IDVMVASEDVLVSVTKDGYIKRTSLRSYSASN--G---------RD-HIISL-LENTTDQILIFTNRGRYLSIPVHELPD-----MGQHLSNLATL-EDE
H--QCIPIR----QAYLVFFTKNGMVKRSELKLYN----KALIALNLK-DEL-V----F--CCDVFIASNKGYGL------I--VGQRAAGVKAIQLK--
-EVVNGQVFDEEPSLVVVTQRGACKRMKLN------RAKRGLVML----RLPHRK-GFFVVH---SLEFMTEDGEMHRVYP-ELTT---YSNGSFIIDSD
H--VTEVWKES-
>tr|A0A0L0QP08|A0A0L0QP08_VIRPA DNA topoisomerase 4 subunit A OS=Virgibacillus pantothenticus GN=parC PE=3 SV=1
IEVMVASEDVLLSVTKDGYVKRTSLRSYSASN--G---------GD-HVIRL-AENTTDKILLFTNKGKYIYIPVHELPD-----IGQHLSNIVAL-EEE
K--TCIPVR----DNYLLFLTKNGMAKRSQFKLYE----KALIALNLK-DEV-V----H--NKDVFITSDKGYGL------I--VGQRAAGVKAIQLK--
-EVVSGQVFDDEPSLVVLTQRGACKRMKLS------RAKRGLQML----RLPHRR-GFFLVN---TIQFKTEDGEVHHVFP-ELSN---YSNGSFIIDTD
H--VLEAWKQI-
>tr|A0A0R1T7Q3|A0A0R1T7Q3_9LACO DNA topoisomerase (ATP-hydrolyzing) ParC OS=Lactobacillus equi DSM 15833 = JCM 10991 GN=FC36_GL001317 PE=4 SV=1
TQILVAQEDVKLLVSQQGYVKRSSLRSFKATG--A---------DD-QVILN-QTNTRDHLLIFTNLGHVIYRPVHEIKE-----TGEHLSQSV-G-ANE
L--YARVFT-I-QAGNLVFATKNGMIKQTALIDLK----RAAVFMKLK--DEVIL---S--DLQVFCVSHGAYGL------V--IGAKTAGVKSMDLR--
-YLAAVLLVKAGDVLGLLSSRGAFKKMSVD------RARRGLQIF----RLPHRL-LATVLP-VTGLTVTTDLGLKVMIDP-IFKL---YSNGSYVIDVE
Q--AFSWEKVV-
>tr|A0A0R1EQ36|A0A0R1EQ36_9LACO DNA topoisomerase IV, A subunit OS=Lactobacillus pobuzihii E100301 = KCTC 13174 GN=FD11_GL000189 PE=4 SV=1
TEVIVASEDVQVLVSRDGYVKRSSLRSVKASG--A---------ED-HVVYS-ATNTLDHLLMFTNKGNMIYRPVHDVTE-----TGEHLSQTV-G-ANE
Y--RAYCFK-I-QGGKFTFATKEGFIKQTKLSDLK----KASKFMKLK-TDEIIL---K--NLQVFCASYNGYGL------V--SGAKAAGVKNMNLR--
-FLASVTLVHESDDLALVTQRGSFKRMKVA------RAKRGVLIL----RLPHKK-FTALLH-DTKLYITTNKNQIVEVDP-EHPS---YSNGSFILDTD
Q--PIWLHSEI-
>tr|A0A0R2KHH3|A0A0R2KHH3_9LACO DNA topoisomerase IV, A subunit OS=Lactobacillus ceti DSM 22408 GN=IV53_GL000802 PE=4 SV=1
TEVLVAQEDVQLLVSHDGYLKRSSLRSFKASP--G---------ED-YPILQ-ETNTLDHLFIFTNKGNLIYRPVHEIRE-----MGEHLSQSV-G-NDE
K--NAYCIK-L-ADLSFLFATANGFIKRTALSDLQ----RPSMYMKLK-DQVVAA---N--SLQVFCATETGYGL------I--LGARAAGVKAMDLR--
-HLVNVLLVTELSQVGILTQRGAFKRMKVA------RARRGVQIL----RLPHRK-FIDVVT-DSLINVITDQSEEIMLEP-EYPF---YSNGSFVIDIL
Q--IDRVYLIE-
>tr|A0A0R1ZKS0|A0A0R1ZKS0_9LACO DNA topoisomerase IV, A subunit OS=Lactobacillus aviarius subsp. araffinosus DSM 20653 GN=FC64_GL000674 PE=4 SV=1
TKVTVAEEDVMVLISKQGYVKRSSIRSYTASG--E---------ED-QPVFQ-GKNTLSHVLMFTNKGNMIYRPVHEITE-----TGEHLSQTI-G-DDE
F--HVEVLK-L-ANGKFVIATKEGLIKQTKLSDLQ----RASMYIKLK-TDEVLT---N---RQVLAITHGGYGL------V--LGAKAAGVKNMDLR--
-YLSAVKLVNNDAVIGIITHRGAFKQMKVS------RARRGVQVL----RLPHRA-AVVTIK-GQEIYVITDHNEIVSIDP-DHSL---YSNGSFVLDTE
Q--VMHAECIL-
>tr|F7QXX5|F7QXX5_9LACO DNA topoisomerase 4 subunit A OS=Lactobacillus ruminis SPM0211 GN=parC PE=3 SV=1
TEVMVAQEDVMLLVSRDGYVKRSSLRSFKASD--E---------ED-VVILM-KVNTLDHLLMFTNKGNVIYRPIHDIVD-----TGEHLSQTV-G-SDE
R--EAFTFD-L-KEGAFVFATKEGMIKQTLLKDLK----RAQTFIKLK-TDEVIM---E--DLQVFCTTHAGYGL------V--TGARTSGVKCMDLR--
-FLISVSLVSEHDEVAIVTQRGAFKKMKVD------RARRGVQIL----RLPHRF-FAKPVI-TDKLLIETTAGEKIELSV-DHPS---YSNGSFVLDTD
Q--PCLVTIVR-
>tr|A0A0R1XPJ8|A0A0R1XPJ8_9LACO DNA topoisomerase IV, A subunit OS=Lactobacillus acidipiscis DSM 15836 GN=FC65_GL001163 PE=4 SV=1
TEVMVAAEDVKALVSRDGYVKRSSLRSFKASG--P---------ED-RVIFS-ATNTLDHLFMFTNKGNVIYRPIHDVTE-----TGEHLSQTV-G-ADE
Y--SAYCFK-L-QGGKFVFATKEGFIKQTELADLK----RASKFMKLK-SDEIIL---K--ALQVLCASYGGYGL------V--SGTKAAGVKAMDLR--
-RLTSVTLVHETDDLALITQRGSFKRMKVA------RARRGVQIL----RLPHRQ-LTTLLQ-NSKLYITTNKDQVITVDP-EHPS---YSNGSFVLDVE
Q--PVWVQNKV-
>tr|F5LNL7|F5LNL7_9BACL DNA topoisomerase (ATP-hydrolyzing) OS=Paenibacillus sp. HGF7 GN=parC PE=4 SV=1
LEVMVTPEDVLVTLSNEGYIKRTSMLSYTRSG--GA--------GD-YLRHL-KENTIESLLIFTNKGQYFLLPVHLIPE-----NGTAIVNIIPI-ADD
R--DMIPVK---EGKSLVFITRKGQVKRTDLKEYY----SGIVACKVG-DEI-L----Q--TKDIMLATKQGMSI------V--MGRAAAGVRGLQLR--
-DVVAADW-VYEGEVLVISDLGYAKRTLLV------RGGKGIGTF--KGKVGSEV-GMFYFK---EITAWNSSGEKTVFKT-QAPL---KSIGKQLVPVS
G--IAALVKNA-
>tr|F8FCZ3|F8FCZ3_PAEMK DNA topoisomerase (ATP-hydrolyzing) OS=Paenibacillus mucilaginosus (strain KNP414) GN=parC PE=4 SV=1
LQAIVTAEDVFVTVSNDGYVKRTGKLSFIRSG--GE--------GD-YLRHL-FDNTLENLLIFTQKGQYFLLPVHAIPE-----NGTAIVNVIPL-PDD
R--HVMALK---PGKSLLFVTRKGQVKRTELKDYA----TGIVAVKIG-DAL-L----L--GLDLLLVSKQGQAI------V--MGRAAAGVRGMQLK--
-DLVAARW-IDEGEVVVITDLGYAKRSLVA------RGGKGVFTF--KGKVGSVR-SAYVVK---DLTAVLSTGERVTFST-QAPI---KSIGKAILPLN
G--VLDVLRLQ-
>tr|A0A0N8PTY5|A0A0N8PTY5_9BACL DNA gyrase subunit A OS=Paenibacillus sp. A3 GN=QJ48_25445 PE=4 SV=1
LEVMVTAEDVFVTLSSEGYIKRTGKLSFIRSG--GE--------GD-YLRYL-LDNTLESLLIFTQKGQYFLLPVHQIPE-----NGTAIVNVIPI-SDD
R--HVLPVK---PGKSLVFVTRKGQVKRTELKEYF----TGIVACKVG-DAV-L----L--SKELLLVTKQGMAI------V--MGRAAAGVRGIQLK--
-DVVAADW-IDEGEVVVMTELGYAKRSLVA------RGGKGIITF--KGKVGSEK-GAFVVK---DLTAILSTGGRVTLST-QTPI---KSTGKCVVPVN
N--VTDILKIT-
>tr|A0A0Q9PRB2|A0A0Q9PRB2_9BACL DNA gyrase subunit A OS=Paenibacillus sp. Soil766 GN=ASG89_06140 PE=4 SV=1
LEVLVTAEDVLVTLSNEGYLKRTSKLSFTRSG--GE--------GD-YLRFL-LDNTIESLLIFTKKGQYYLLPVHQIPE-----NGTAIVNVIPI-AED
R--NVIPVK---PTKSLVFVTRKGQVKRTELKEYM----NAIVACKLG-DEV-L----H--TKEILLVTKQGMSI------V--MGRAAAGVRGIQLK--
-DVVSAEW-IYEGEVLVISDLGYAKRSLVV------RGGKGIITF--KGKVGSAI-RTFIVK---LITAVMSNGEKLRFST-TAPL---KAQGKLLIPVT
T--IVEILRFP-
>tr|A0A0Q9KBR4|A0A0Q9KBR4_9BACL DNA gyrase subunit A OS=Paenibacillus sp. Soil522 GN=ASG81_19580 PE=4 SV=1
LEVLVTPEDVLVTLSHEGYVKRTSMLSFTRSG--GE--------GD-FVRGL-FENTIDNLLLFTRKGQYYLLPVHQIPE-----TGTAIVNVVPI-PDD
S--SVIPIK---STASLVFVTKRGQVKRTELKEYA----TAVAACKVS-DEV-I----V--SKQIMLITKQGMSI------V--MGRVATGVRGIQLK--
-DIIAAEW-VAEGEVLVITDIGFAKRSLLL------RGGKGVQTF--KGKVGASV-GAYYCK---EIVAVTASGAKLAAVS-KAPI---KAVGKLVFPVE
N--ITNTLARS-
>tr|A0A0D5NQ56|A0A0D5NQ56_9BACL DNA topoisomerase 4 subunit A OS=Paenibacillus beijingensis GN=parC PE=3 SV=1
LEVMVNPEDVIVSLSRDGYVKRTSILSFTRSG--GD--------GD-VIRFM-LENTVHSLLVFTRKGQYYLLPVHQIPD-----AGTAIVNVIPL-PDD
S--SVIPVK---TGLSLVFFTKRGQVKRSELKDYA----TAIAACKLA-DEV-I----T--SGQIVLISRQGMGI------V--MGRVSAGVRGMQLK--
-DIASALR-TREGEIFVISDLGYGKRTLLS------RGGKGIATF--KGKVGSAA-GAHYCT---ELVAITAGGKHYRIPT-KTPL---KSIGKTVVSLD
S--IIDLFPQA-
>tr|C6CYI7|C6CYI7_PAESJ DNA topoisomerase 4 subunit A OS=Paenibacillus sp. (strain JDR-2) GN=parC PE=3 SV=1
LEVMVQSEDVIVTLSEEGYMKRTSMLSFTRSG--GD--------GD-AISSV-YENTIDNLLLFTRKGQYYMLPVHQIPE-----TGTAVVNIVPI-PDD
S--AIIPVK---PGASLVFVTKRAQVKRTELKEYM----TAIAAAKVA-DEV-I----T--TKQLLLVSKLGMSI------V--MGRVAAGVRGMQLR--
-DLIAAEW-VAEGEVLVVTDLGYAKRTLLL------RGGKGVQTF--KGKVGSAV-AALYCK---GIIALTSQGAQLAASS-KAPI---KSIGRILLPME
N--ITTIFVRP-
>tr|A0A0Q4RMJ6|A0A0Q4RMJ6_9BACL DNA gyrase subunit A OS=Paenibacillus sp. Leaf72 GN=ASF12_01085 PE=4 SV=1
LEVMVTPEEVLVTLSNEGYMKRTSMLSFTRSG--GE--------GD-IIRGL-YANTIDNLLLFTKKGQYYTLPVHQIPE-----TGTAVVNIVPI-PDD
A--SVIPVK---PGASLVFVTKRGQVKRTELKDYM----TAIAACKVA-DEV-I----L--TKQLMLVSKQGWSI------V--MGRVAGGVRGMQLK--
-DLIAADW-VGEGELFVISDLGYAKRSLLL------RGGKGVQTF--KGKVGSAV-YAVYCK---DLIALASSGAKLPMTT-KSPI---RSIGRTIVPLE
N--LTAVIVRP-
>tr|A0A0R1ZWD8|A0A0R1ZWD8_9LACO DNA topoisomerase IV subunit A OS=Lactobacillus malefermentans DSM 5705 = KCTC 3548 GN=FD44_GL001894 PE=4 SV=1
TKVMVADEEVIVQVSHDGYLKRTGIRSYKASD--E---------ND-FPIFL-QKNTLNHLFMFTNKGNLIYRPVYEIAD-----TGEHISQTI-G-DDE
E--STFAFK-L-ETGHFLIATSDGYIKQTEFAALT----RATTFEKAK-ATRIVN---P--DNTVLLMSRLGQGL------V--NGARTTGVKSMDLR--
-DVVDLQLVNEADTIAMVTQRGSFKKLPVK------RARKGVMVL----RLSHEV-DFIKLP-TTPLEIITARNLIHDVLP-DHPN---YSNGSFVIDVD
E--PTSIRAKI-
>tr|A0A0R2EPJ8|A0A0R2EPJ8_9LACO DNA topoisomerase IV subunit A OS=Lactobacillus similis DSM 23365 = JCM 2765 GN=FD14_GL002155 PE=4 SV=1
TEVMVPDEDVVVLVSRDGYLKRSGVRSYNASD--P---------DD-YPIFT-EKSTLNHLYMFTNKGNLIYRPVHEITD-----TGEHISQTI-G-ADE
Q--ATYAFE-L-APGEFLIATDDGYVKRTEFKSLL----RAIVYEKLK-EAHVVD---A---TSILLMSKLGLAL------V--NGARTTGVRSMNLG--
-DVVDLQLVTDADTVSLITQRGAFKKMAAK------RARKGVQVL----HLPHEV-DFIKLA-TAALEVITDRRRMHDILP-EHPL---YSNGSFVIDTE
E--PEILRLKP-
>tr|A0A081BID0|A0A081BID0_9LACO DNA topoisomerase 4 subunit A OS=Lactobacillus oryzae GN=parC PE=3 SV=1
TKVMIADEEVIVQVSHDGYLKRTGIRSFKASD--E---------DD-FPIFL-QKTTLNHLFMFTSKGNLIYRPVYEITD-----TGEHISQTI-G-DDE
E--ATHAFK-L-EAGHFLIATNDGYIKQTEFAALT----RAMTYEKTK-QTRVVN---P--TDSILLMSRKGQGL------V--NGARTTGVKSMDLR--
-DVVDVQLVHDDDVVAMITQRGSFKKLPTE------RARKGVMVL----RLSHEV-DFIKLE-TTPLEVITTRGLIHDILP-DHPV---YSNGSFVIDVD
E--PTQIRTKM-
>tr|A0A0R1U6H3|A0A0R1U6H3_9LACO DNA topoisomerase (ATP-hydrolyzing) OS=Lactobacillus pantheris DSM 15945 = JCM 12539 = NBRC 106106 GN=FC50_GL001632 PE=4 SV=1
TTVLVADEQVMVQVSRDGYVKRSSLRSFQAVS--P---------ED-APVYA-AQSTLTHLYIFTTKGNMIYRQVHELAD-----SGEHLSQTV-G-ADE
Q--AVYAFD-L-GDGAFTIGTSDGYIKQTLLAELQ----KPIVAIKLK-AATVTD---A--ELYVFVATKIGYGL------V--SGARAAGVKLINLK--
-DVANFAVLDNGATVGILTQRGAFKRMRVS------RAKRGLQIL----RLPHRV-AMVLL--GMTLDVTTDQGTQTNIKP-DHPL---YSNGSFIIDTD
V--PVAVVPHL-
>tr|A0A0R2C9N3|A0A0R2C9N3_9LACO DNA topoisomerase (ATP-hydrolyzing) OS=Lactobacillus thailandensis DSM 22698 = JCM 13996 GN=FD19_GL000368 PE=4 SV=1
TTVLVADEQVMVQVSRDGYVKRSSLRSYQAVS--P---------ED-APVYT-AQSTLTHLYIFTTKGNMIYRQVHELAD-----SGEHLSQTV-G-ADE
Q--SVFAFD-L-GDGAFTIGTSDGYIKQTLLSELQ----KAIVAIKLK-DATVTN---A--ALTVFVATYGGYGL------V--SGARAAGVKLINLK--
-DVANFAVFTQNAVVGILTQRGAFKRMRVS------RAKRGLQIL----RLPHRV-AMMLL--GMTLAVTTDQGQQITLNP-DHPL---YSNGSFVIDTD
Q--PVAVVPQV-
>tr|L0ECC4|L0ECC4_THECK DNA topoisomerase 4 subunit A OS=Thermobacillus composti (strain DSM 18247 / JCM 13945 / KWC4) GN=parC PE=3 SV=1
LEVMVASEDVLVTLSQEGYIKRTSRLSFTRSG--GD--------GD-IVRLV-LENTLDQLLLFTRKGSYFLLPVHQIPE-----TGTALVNVVPL-ADD
G--GIVPVR---EDLSLLFVTKRGQVKRTALKEYQ----GPIAACRLA-DEV-V----L--TQQLMLVTKLGMSI------V--MGRVAAGVRGIMLK--
-DVAAALL-VKEGEVLVVTDLGWAKRSLLL------RGGRGLATF--NSKGGSRI-GAFHCK---RYTLATSSGASFTFST-DTPI---RSGGKRVAALD
Q--AVCCFRRP-
>tr|L5N449|L5N449_9BACI DNA topoisomerase 4 subunit A OS=Halobacillus sp. BAB-2008 GN=parC PE=3 SV=1
LEVTVASEDVIVSVTKDGYLKRTSPRSYGASN--G---------GD-HLLRL-FENTTDTILLFTNLGKYLFLPVHKLPD-----LGQYISNIVQV-DNE
F--EAIPIR----DRYLLFFTKNGMVKKSELGLYK----KALVAINLK-DEV-V----H--NSDIFIASNKAYGL------V--VGQRASGVKAITLK--
-EVVSGQVFKAP-SILLYTHRAAVKRMRLK------RAKRGLIML----RLPHQI-DVHLVQ---QIVLMTEKDQITELKP-DFKA---YSNGSYVLDTE
Q--VVEAWLKS-
>tr|K2HAW8|K2HAW8_9BACI DNA topoisomerase 4 subunit A OS=Salimicrobium jeotgali GN=parC PE=3 SV=1
LEVMVPSEDILTSVTRDGYVKRTSLRSYGASQ--E---------GD-YLLSL-MENTTDTLLLFTNRGKYLYLPVHRLPD-----LGQHVTNLVPV-EGE
K--EAIPVR----DDYLTFVTKNGMVKRSLLKDYQ----KPLVGINTK-DEV-V----H--RKDIMLASNKGYCL------I--VGARAAGVKGMQLK--
-EIVSGEVFDPR-TVLVVSHRGAVKRMDLR------RAKKGNVVF----RLPHTI-QMLVVD---HIRIVTDKEA-IEVQP-QYRS---YSNGTFVIDTE
N--VTGAWRKV-
>tr|A0A024P1Z6|A0A024P1Z6_9BACI DNA topoisomerase 4 subunit A OS=Halobacillus karajensis GN=parC PE=3 SV=1
LEVTVASEDVLVSVTKDGYIKRTSLRSYAASN--G---------GD-HLLGL-FENTTDTILLFTNLGKYLFLPVHKLPD-----LGQYISNIVQV-DDE
Y--KAIPVR----EQYLIFFTKNGMVKKSELKLYQ----KALVAINLK-DEV-V----H--DSDLFIASKKAYGL------V--VGQRAAGVKAINLK--
-DVISGQTFQADPSILLTTHRGAVKRMRLK------RAKRGVIML----RLPHQI-DVHLVT---QVMLMTDKDESIIVNT-DFKV---YSNGSYVLDTE
K--VTEAWVKP-
>tr|A0A0B0DB27|A0A0B0DB27_9BACI DNA topoisomerase 4 subunit A OS=Halobacillus sp. BBL2006 GN=parC PE=3 SV=1
LEVTVASEDVLVSVTKDGYVKRTSLRSYAASN--G---------GD-HLLRL-YENTTDTILLFTNLGKYLFLPVHKMPD-----LGQYISNIVQV-EDE
F--EALPIR----DQYLLFFTKNGMVKKSELKLYQ----KALVAINLK-DEV-V----H--DSDLFIASNKAYGL------V--VGQRAAGVKAIHLK--
-EVVSGQVFDADPSILLTTHRAAVKRMRLK------RAKRGVIML----RLPHRV-DVHLAR---QVVIRTNKEETTIVNT-DFKA---YSNGSYVMDTD
Q--VTEAWIKP-
>tr|I0JMY6|I0JMY6_HALH3 DNA topoisomerase 4 subunit A OS=Halobacillus halophilus (strain ATCC 35676 / DSM 2266 / JCM 20832 / NBRC 102448/ NCIMB 2269) G
LEVTVASEDVLVTVTKDGYLKRTSLRSYAASN--G---------GD-HLLRL-LENTTDTILLFTNLGKYLFLPVHKLPD-----LGQYISNIVQV-EDE
H--EAIPVR----DQYLLFFTKNGMVKKSELKLYQ----KALVAINLK-DEV-V----H--HSEIFIASNKAYGL------V--VGQRAAGVKAIHLK--
-EVISGQIFQKDPSVFLSTHRAAVKRMRLK------RAKRGVIML----RLPHRI-DVHLVH---QVILKTEKEESTTLNV-DYKA---YSNGSYVMDTD
N--ISEAWVKP-
>tr|A0A0M9D682|A0A0M9D682_9LACO DNA topoisomerase 4 subunit A OS=Lactobacillus kunkeei GN=parC PE=3 SV=1
KTITVPEEDVVVLVSHDGYLKRSSVRSYKASE--V---------DD-YPIFL-EQTTLQHLFMFTNKGNLIYRPVHEITD-----TGEHISQTI-G-ADE
K--KVMSFK---ETGKFVISTSDGYIKQTEFDKLT----RPAVFEKLK-SANVVN---A--NPNVFIASNVGLAT------V--SGARSTGVRSMDIR--
-EVVDVQLVEQ-DKVGMITQRGFYKNMKVD------RARRGVQVL----KLPHEV-DFVKLE-FNPIRVFTNRRRVHDIMP-DHPV---QSNGSAVMDVD
E--PTSMTVLH-
>tr|A0A0M9D4H3|A0A0M9D4H3_9LACO DNA topoisomerase 4 subunit A OS=Lactobacillus apinorum GN=parC PE=3 SV=1
KTITVPEEDVVVMVSHDGYLKRSSVRSYKASD--V---------DD-YPIFL-EETTLQHLFMFTNKGNLIYRPVYEITD-----TGEHISQTI-G-SDE
A--KVMSFK---ETGKFVISTSDGYIKQTEFDKLA----RPAVYEKLK-SAYVLN---E--NPLVFIASNVGLAT------V--SGARSTGVRSMDIR--
-EVANVALVRE-DVVGMITQRGFYKNMKVS------RARRGVQVL----KLPHEV-DLVKLE-YNPIQVVTDRRRTHDIMP-EHPI---QSNGSALLDVD
E--PLKMMVLH-
>tr|A0A0R2H1C2|A0A0R2H1C2_WEIVI Dna topoisomerase (Atp-hydrolyzing) OS=Weissella viridescens GN=IV50_GL000033 PE=4 SV=1
QTVTVVDEDVMLLVSKSGYVKRSSIRSYTASG------------DD-EIVFV-DRNTLQHVFMFTDRGNVVYRPVHEIAE-----AGEHLSQTITG-NDE
L--AVKVVQ---LDGEWVVATSDGLIKRTKFNDLA----KPTPFIKLK-SAYVVD---D--QYEVVLTSYQANGL------V--SGARTAGVKAMALSE-
-DITGLALNDTPIAIALMTNRGAFKWMSID------RARKGVAVM----RLSHRV-AMLGLD-PSPVTVLTSSDKVFDINP-DHPK---YSNGSFVIDTQ
D--PVAMHKYQ-
>tr|A0A069CSI3|A0A069CSI3_9LACT DNA topoisomerase 4 subunit A OS=Weissella oryzae SG25 GN=parC PE=3 SV=1
RTVTVADEDVVVLVSREGYIKRASVRSYTASR------------DD-EPVYL-GKNTRQHIFILTNLGNVIYRPIHEIPE-----AGEHLSQTITG-AEE
V--TVKIVD---LNGEWLITTSDGMIKRMAFSDLA----RSMVLIKLK-PAQIIG---E--HGEVMIVTHGTYAL------V--TGPRTAGVKAINLAD-
-YVSSS---VVTKALALISNRGAFKWMAVT------RARKGVMIM----RLPHQV-AAQVVT-PIKLRITTDQNKHFDFLP-EHPL---YSNGSFIIDTD
D--PTRMELFL-
>tr|C5RBE2|C5RBE2_WEIPA DNA topoisomerase 4 subunit A OS=Weissella paramesenteroides ATCC 33313 GN=parC PE=3 SV=1
STVTVADEDVAVLVSKMGYVKRSSLRSFKASG------------DD-EPLFI-ERNTLQHMFIFTNKGHVIYRPIHELPE-----PGEHLSQSVSG-IDE
E--HVEIVN---LEGTWLSATNDGYIKQFNFEDLT----RSTVYMKLK-DSSIIG---S--DRTVILTTKHAVGL------V--SGNRTAGVKAMNLAS-
-NVN---MSTAKQALAIITHRGAFKWMPVS------RARKGVAIM----RLSHEI-ATIVID-PAALSIYTSRGKRFDVSP-DHAL---YSNGSFIIDTD
D--PTTIKLYD-
>tr|G0UHD5|G0UHD5_9LACT DNA topoisomerase 4 subunit A OS=Weissella thailandensis fsh4-2 GN=parC PE=3 SV=1
STVTVADEDVAVLVSKMGYVKRSSLRSYKASG------------DD-QTLFV-DRNTLQHMFIFTNKGHVIYRPIHELPE-----PGEHLSQSISG-VDE
E--RVEVVD---LEGTWLSATNDGYIKQFSFEDLT----RSTVYMKLK-DAVIVG---P--NRTVVLTTRHAVGL------V--SGNRTAGVKAMNLAD-
-IVG---MATVKQALAIITHRGAFKWMSVD------RARKGVAIM----RLSHEV-ATIIVD-PAPLSIFTSRGKQFDVSP-DHGL---YSNGSFIIDVA
D--PVSIRLYD-
>tr|H1X671|H1X671_WEICO DNA topoisomerase 4 subunit A OS=Weissella confusa LBAE C39-2 GN=gyrA PE=3 SV=1
QTVTVADEDVVMLVSRAGYVKRASVRSYTASG------------DD-EPVFV-EKNTLQHAFIFTNKGNVIYRPVHELPE-----AGEHLSQTITG-ADE
V--DVRIMS---MAGEWVVATSDGLIKRTPFADLA----KATMLIKLK-DATVVG---D--GKSVVLASENAMGL------V--TGNRTAGVKAMNLEG-
-RVK-MA--VAKQAIAVVSNRGAFKWMPVT------RGRKGVAIM----RLPHRA-AMMVVD-PTPLTVMTDRDKQFDISP-DHPM---YSNGSFIIDVE
A--PVRMHAYV-
>tr|A0A0R2JIM7|A0A0R2JIM7_9LACT Dna topoisomerase (Atp-hydrolyzing) OS=Weissella minor GN=IV67_GL000672 PE=4 SV=1
QNVTVADEDVMMLVSKSGYVKRSSIRSYNASG------------DD-EVIFV-NRNTLQHLFMLTDRGNVVYRPIHEIAD-----AGEHLSQTITG-AEE
L--AVKVVD---LAGEWVSVTSDGLIKRTKFSDLA----KPTPFIKLK-DAYVVN---D--NYDVILASYQANGL------V--SGARTAGVKAMALG--
-DITGMALSDNDQALAFVSNRGAFKWMPVD------RARKGVAIM----RLPHRV-SMVGIH-PEPLTILTDTDKLFDINP-DYPK---YSNGSFVIDTE
S--PVMMHVLQ-
>tr|A0A0R2FYT3|A0A0R2FYT3_9LACT Dna topoisomerase (Atp-hydrolyzing) OS=Weissella halotolerans DSM 20190 GN=IV68_GL000442 PE=4 SV=1
ETVTVVDEDVMLLVSKNGYVKRSSLRSYGASG------------DD-EVVFM-DENTLEHVFMFTDHGQVIYRPVHEVAE-----PGEHLSQTITG-TDE
Q--AVKVVK---LNGEWIAATSDGHIKRFAFADLT----KSTPYMKLK-DAYVVN---S--HYTVLLTSYQANGL------V--HGLRTTGVKAMSLAQ-
-DLTSLSLVDDSLALALISNRGAFKWMPVD------RARKGVAVM----RLPHRM-AAALVN-PTPLRILTLGDRVFDILP-DHPL---YSNGSFVIDTE
V--PVAMYPLV-
>tr|J6Z2M4|J6Z2M4_ENTFC DNA gyrase subunit A OS=Enterococcus faecium 505 GN=gyrA PE=3 SV=1
DEDLIEEEEIVITLTNNGYIKRLANNEFRAQRRGGRGVQGMGI-NDDFVKNLVSCSTHDTLLFFTNNGKVYRAKGYEIPEYGRTAKGIPIINLLGI-DSE
SIQAIIAVT--EEGHYLFFTTRQGTVKRTSVTAFAN-RSNGLIAIGLKEDDELVNVL-TDG-SNIIIGTHNGYSVTFKE--VRDMGRTASGVRGIRLR--
-EVVGAALMKENQEVLVITEKGYGKRTKVSEYPVKGRGGKGIKTANIT-E-NGPLAGLTTVSD-EDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKME
D-KVVTMAAVE-
>tr|R6TP39|R6TP39_9STAP DNA topoisomerase 4 subunit A OS=Staphylococcus sp. CAG:324 GN=parC PE=3 SV=1
TEEFIAKEDVMLLITHDGYLKRLSKKAFLATT------------GD-VITDI-YESTTDTLIQFTDKGNYIFLPIHKIPE-----LGFHVSTLIGM-ENE
K--FSFPVD--KE-RYVLLATASGLIKRIKLSSLY----KALKATKIK-D-YVVS---T--NYEVVIATKDGYMN------V--IEPASFGVKSIELK--
-PVVGAKYVS-KDIVLLLTNRGNIKRLRPE------KNNVGKMYL----KVMHEI-DLEVIH--ANSDYIFCEKGYVEI---DYTL--RADNGKKFVSNN
G-YIVICRNGN-
>tr|R5FQW4|R5FQW4_9FIRM DNA topoisomerase (ATP-hydrolyzing) OS=Coprobacillus sp. CAG:698 GN=BN756_00792 PE=4 SV=1
-KVLIAKEDAVIIITKDGYIKRMSPKVY-ASDE------K----ED-FVLAKYDVTTLDTLLFFTDKGSYVYLPVQNIPER-PKELGRNIAVMA-TPD-E
K--FSVPIS---ADRYVLFTTKHGLTKRTHIRELVA-RYKALKATKLR-D-EVVS---N--EVM--VVTKEGYML------ISLFAPPSFGVKAIELKR-
-PVLGAFYVN--DVLLVLSEKGGIRKFKC-DVP-GKKIHVGKLCV--GP--N-GL-DFE---------IIHEKSETSK----CYLV-DV---EINLEEDV
G---------N-
>tr|A0A0R2BSB3|A0A0R2BSB3_9LACO DNA topoisomerase IV subunit A OS=Lactobacillus dextrinicus DSM 20335 GN=FC84_GL001396 PE=4 SV=1
TSVMVTSEEVELLVSHDGYIKRSSLRSYQATG--S---------ED-YPIFE-GSNTLDHLFIFTTKGNLIYRPVHEIAD-----MGQHLSQDV-G-DNE
S--AAYVYS-L-QNGQFVLTTSDGYIKQVAFNSLL----RPQMAVKLK-DAQVVN---L--FAEVYLFSRHAYGL------V--VGAKAAGVKGINLK--
-DLVGSWSLTAEPALAILTQRGAFKKMPLT------RALRGLQVL----RLPHEV-ATQLLL-DQKLKIYTEKNQQVELMI-NVPT---YSNGSFVLDVE
D--PVRMALID-
>tr|A0A0R1VY66|A0A0R1VY66_9LACO DNA topoisomerase IV subunit A OS=Lactobacillus concavus DSM 17758 GN=FC15_GL001244 PE=4 SV=1
TSVMVTAEDVQVMVSHDGYLKRSSLRSFQATD--A---------ED-YPVFM-ATNTLDHLFIFTTKGNLIYRPIHEIDE-----MGQHLSQDV-G-ADE
S--AAYVFK---QVGQFVLVTSDGYIKQVAFESLL----RPQQAIKLK-ASQVIG---L--FADTYLFTKNALGI------V--VGAKAAGVKAANLK--
-DLVAAIFTTVDNAVGILTQRGAFKKMPLS------RARRGLLML----RLPHEV-AASLLT-EQALEVTTDQNQKVTVTI-DVPL---YSNGSFILDPE
S--PIRMTKLE-
>tr|A0A0G1SCR8|A0A0G1SCR8_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWA2_47_16 GN=gyrA PE=3 SV=1
EEDLIPDTESVLVLTKGGYIKRTDPEEYRKQRRGG-G--ILD--ED-FVTMFLTATTHSDLLFFTDKGKAYQIKMYEIPEK-RATKGKSIVNFI-SAD-E
K--SILAMPQ--STLSLLMVTKSGVGKKTAAKNFHD-R-SGLIAIKLQ--DQLIS---V---DDCIVVTMNGQSI------VREMGRNAGGVRVVRLGN-
-ALVGADIIKKDPSLLVIMENGYGKKTDL-EYK-QKRGGSGIKTA---TSKTGKI-ASKVVD-IEEVIAISKKSQVIRVAL-EIPI-GR---GVRIMKLR
G-NIASLTCL--
>tr|A0A0G1MTV0|A0A0G1MTV0_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWB1_44_7 GN=gyrA PE=3 SV=1
LEDTIPDEESVLVLTTGGYVKRTDPSEYRKQKRGG-G--VLD--ED-FVSIFLTASTHSDLLFFTDKGKVYQIKMYEIPEK-RATKGKSIMNFL-SAD-E
K--SILPIP--KSALATLLLTKNGTAKKVDAASFHD-R-SGIIAIRLD--DALQA---VD---QVIAASAKGQSI------IRVMGRAAGGVRAMRLGK-
-SIVGADIIKKNPRFLVVMENGYGKTTAL-EYK-QKRGGSGIKTA---TAKTGAM-AAKVVT-EEELVAISKKSQVIRVDI-EISA-GR---GVRIMKLR
G-SIASLVCL--
>tr|A0A0G1SM14|A0A0G1SM14_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWA2_47_21 GN=gyrA PE=3 SV=1
MEDLVADEESVLVLTKGGYVKRTDPEEYRKQRRGG-G--VLD--ED-FVTMFLTTTTHSELLFFTDRGKAYQIKMYEIPER-RATKGKSIMNFL-AAE-E
K--SVLPMP-----AAILMVTKAGVAKKVDSKGFHD-R-SGIIAIRLD--DELKH---VD---EAAVATGKGQSI------IRVMGRGAGGVRAVRLGK-
-GVVGADVVRKNPRLLVISENGYGKLSEL-EYK-QKRGGSGIKTA---TAKTGSI-TSKVVT-ETELVAISKKGQVIRVAL-EIPT-GR---GVRIMKLR
E-SLASVITI--
>tr|A0A0G0ZI19|A0A0G0ZI19_9BACT DNA gyrase subunit A OS=Parcubacteria (Nomurabacteria) bacterium GW2011_GWC2_42_20 GN=gyrA PE=3 SV=1
LEDMIPDEESMLVYTKGGYIKRTNPGEYRQQNRGG-G--VLD--ED-FITLFMSATTHSDMLFFSDKGKAYQIKMYDIPEK-RATRGKSIMNFI-ASE-E
K--SILSMPD--SNLSLFMVTKHGTIKKCGAESFKD-R-NGIISIKLD--DELIA---T---DDIILTTAKGQAI------AREMGRAAAGVRGMKLGG-
-FIIGADVIQKKPELLVMSENGYGKKTAI-EYK-QKRGGSGIKTA---TAKIGQM-VAKVVT--SELVAISKNSQVIRITM-DVPT-GR---GVRIMKLR
G-SIASLSCL--
>tr|A0A0G0RJ97|A0A0G0RJ97_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWE1_40_20 GN=gyrA PE=3 SV=1
VEDLIPDEENALVLTAGGYIKRTNPDEFRKQKRGG-G--VMD--ED-FVTNLLIASTHSDLLFFTDKGKSYQTKMYDIPER-RATRGKSVMNFL-PSG-E
K--SILPMPK--SESSLMMVTKHGIAKKVATSSFHD-R-SGIIAIKLD--DSLIS---V---DTVMVVTARGQSI------IREMGRTAMGVRGMKLGG-
-EVISAEPISHSATLMVISENGYGKRTDI-EYK-QNRGGSGIKTA---TPKTGKI-SAKVFA--AEVVAISKKSQVIRVDA-EINV-GR---GVRVMKLR
G-SIASLICL--
>tr|A0A0G0Q481|A0A0G0Q481_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWF2_39_8b GN=gyrA PE=3 SV=1
LEDLIPDEENALVLTAGGYIKRTNPDEFRKQKRGG-G--VLD--ED-FVTMLLITSTHSDLLFFTDKGKAYQTKMYDIPEK-RATKGKNVMNFL-PSG-E
K--SILPMPK--SEASLMMVTKMGQTKKCLAASFHD-R-SGIIAIKLD--DALVS---V---DTVIIVTSKGQSI------IRETGRTAMGVRGIKLAD-
-TVISAEAVPNNGTLMVISANGYGKCTDI-EYK-QHRGGSGIKTA---TPKTGQI-SAKVFT--TEIVAISKKSQVIRVDA-EIPV-GR---GVRVMKLR
G-SIASLICL--
>tr|A0A0L0LCM4|A0A0L0LCM4_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium C7867-006 GN=gyrA PE=3 SV=1
VEDLIPDEENALVLTAGGYIKRTNPDEFRKQKRGG-G--VLD--ED-FVTMLLIASTHSDLLFFTNKGKAYQTKMYDIPER-RATKGKSIMNFL-PGG-E
S--SVLPMPK--ETSSLMMVTKQGVAKKVATASFHD-R-SGIIAIKLE--DELVS---T---DTVIVVTQKGQSI------IREMGRTAMGVRAIKLGG-
-VVISAETVPNNGSLMVISANGYGKCTDI-EYK-QNRGGSGIKTA---TPKTGNI-SAKVFA--GEIVAISKKSQVIRVDA-EIPV-GR---GVRIMKLR
G-SIASLICL--
>tr|R5ZKF1|R5ZKF1_9FIRM DNA topoisomerase 4 subunit A OS=Firmicutes bacterium CAG:536 GN=parC PE=3 SV=1
KRAMVADEMVMVPITRDGYIKKVSMRSYNASN--T---------SD-SVLAY-GSSTLDTLLFFTNRGTYGYLPVYEIEE-----LGSHLGNYIKM-DNE
K--QAYFLR--PN-VQVIMASQFGMIKRSRLSDFE----KSMVCMKIG-D-QVVS---Y--EDSIAVVSQQGYAL------V--MTLRTKGVKAMNLG--
-DIADVTILQ-DKQVLLVGDKAQMKRLKVE------RPAKGNRLY----KVPVYK-SIYAVE--G--FDL-MSEDPIHFEA-DISL---SATFSTPFGKL
E--IQS------
>tr|J3JPL4|J3JPL4_STRRT DNA gyrase subunit A OS=Streptococcus ratti FA-1 = DSM 20564 GN=gyrA PE=3 SV=1
DEDLIEEEDVLITLSNKGYIKRLGQDEFRAQKRGGRGVQGTGV-DDDFVRELVSTSTHDSMLFFTNQGRVYRLKGYEIPEYGRTAKGLPVVNLLKL-DGE
TIQTIINVN--H-DKYLFFTTRQGLVKRTSVSAFGN-RQNGLKALNLRDGDELINVL-TDG-NDIIIGTRQGYSVRFNE--VRNMGRSATGVKGVNLR--
-QVIGAAHIVDNQDVLTITEKGYGKQTPANQYPTKGRGGKGIKTANIT-S-NGPLAGLVTVND-EDIMVITDTGVIIRTSVANISQTGRSAMGVKVMRLD
Q-KIVTFALVK-
>tr|G5JVC0|G5JVC0_9STRE DNA gyrase subunit A OS=Streptococcus macacae NCTC 11558 GN=gyrA PE=3 SV=1
DEDLIEEEDVLITLSNNGYIKRLGQGEFRAQKRGGRGVQGTGV-DDDFVRELVSTNTHDAMLFFTNRGRVYRLKGYEIPEYGRTAKGLPIVNLLKL-ETE
TIQTIINVK--H-DKYLFFTTKEGIVKRTTVSAFAN-RQNGLKALNLRGGDELINVL-TNG-EDIIIGTRSGYSVRFKE--VRNMGRTATGVKGVSLR--
-KVIGAAAVSDSQEVLTITEKGYGKQTAASEYPTKGRGGKGIKTVNIT-E-NGQLAGLVTVDD-EDIMLITNTGVIIRTSVANISQTGRSAMGVKVMRLD
E-KIVTFALVK-
>tr|V6Z2I3|V6Z2I3_STRAG DNA gyrase subunit A OS=Streptococcus agalactiae LMG 14747 GN=gyrA PE=3 SV=1
DEDLIEEEDVLITLSNKGYIKRLAQDEFRAQKRGGRGVQGTGV-DDDFVSQLVSTSTHDILLFFTNLGRVYKLKGYEIPEYGRTAKGLPVVNLLKL-DGE
FIQTMINAR--K-DHYFFFTTYAGVVKRVPTSEFDN-RQNGLKALTLKDNDQLINVL-TTG-DDIIIGTSAGYSVRFNE--VRTMGRTAAGVRGVKLR--
-EVVGASTITDDQEVLIVTEKGYGKRTSAEEYPTKGRGGKGIKTANIT-D-NGALAGLVTVSD-EDVMLITNKGVVIRTNVSNISQTGRSTMGVRLMRLD
T-KLVTFALVD-
>tr|E8KBX4|E8KBX4_9STRE DNA topoisomerase 4 subunit A OS=Streptococcus peroris ATCC 700780 GN=parC PE=3 SV=1
TVSLIAEEETYVSVTKAGYIKRTSPRSFAAST--L---------DD-RLIFT-QVKTTQHLLMFTTLGNVIYRPIHELAD-----IGEHLSQTITN-ENE
E--YAEVVD---ATT-YFAATRLGQIKRVERKEFT----KSVKYAKLK-SDQIVA---K---DDVLLISKNGYAL------V--VGAKAAGVKAMNLK--
-DIQVAFICNT-SSFYLLTQRGSLKRVSTE------RAKRGLQVL----RLPHRF-LAGTVSVDQTLVVQSNKGIIYETIL-DLNL---TSNGSFISETI
D--VFDAYLKE-
>tr|D6S558|D6S558_9LACO DNA topoisomerase 4 subunit A OS=Lactobacillus jensenii JV-V16 GN=parC PE=3 SV=1
EKALVAEEDVRVLVSRDGYLKRSSLRSFQSTN--D---------FD-KVVFE-KTSTLTNLYIFTNKGNVIFRPVHELVE-----PGQHLSQEL-G-DDE
Q--AVFELA---SRLNFLLATNDGYIKQLALADIQ----RAMIAMKLK-ASRVVR---S--KKEITLFTNHAYAV------I--SGARAAGVKSVNLK--
-DVVDYVTVLPMMKLGIVTQRGAFKEFKYE------RAKRGVLVL----RLPHRA-GVVLFA-NHELLVETSSARTMTIKT-DFPL---YSNGSFVIDPI
D--PTSLTLGK-
>tr|A0A011RLM9|A0A011RLM9_9LACT DNA topoisomerase 4 subunit A OS=Alkalibacterium sp. AK22 GN=parC PE=3 SV=1
KEVLVAEEEVIVSVTKEGYLKRTSLRSYGASN--P---------GD-YSLYT-EKSTLQQIILFTSKGNAINRPVHEIPD-----LGQHISQSI-S-EEE
T--AVFGLN---ENERFVFVTKEGYIKQTAVSDYK----RSHTAIKLK-TDECLS---Q--QLDVFLVTQMGFGL------V--VGATASGVKSINLK--
-DVVDGIIFDPNKAVMLVTHRGAVKKMNVS------RAKRGLLVL----RLPHRA-LMIDVL--AAYTITTDKNQKQRLLP-NYAY---YSNGSFILDED
D--PV---DAY-
>tr|V6IXK2|V6IXK2_9BACL DNA topoisomerase 4 subunit A OS=Sporolactobacillus laevolacticus DSM 442 GN=parC PE=3 SV=1
LEVMVAAEEVMVSLTKHGYIKRSSLRSFSASA--D---------TD-HTLFQ-KQNTTETLLVFTNMGRYIYLPVHEIQD-----LGQHIASLVPI-DEE
E--SAIPVS---DGLFITFFTKLGMVKRTKLVEYK----KPLTALKLK-DVC-V----F--QCDLVVATSMGYGL------A--VGLRAAGVKAVQLK--
-DLAGGVALPSL-HLFIATDRGAVKKMAIE------RPRRGVQLL----RLPHHV-GVAFVD---RIVLGTDKGKLCSVLS-DLRV---YSNGSFVLDQD
D--VIDIWTDV-
>tr|K9EDZ2|K9EDZ2_9LACT DNA topoisomerase 4 subunit A OS=Alloiococcus otitis ATCC 51267 GN=parC PE=3 SV=1
TQVLVSEEDVMVTVTQGGYLKRTSIRSYKASQ--V---------DD-LVIFM-QESTLDQLLIFTSKGNVVNRPVHELPD-----IGEHLSRTI-P-GDE
E--KVYPYR---AGKRYVFITRDGYIKQSPETEFE----RASTAIKLK-QDRLQA---P--DYDVFLASYKGYGL------V--VGAQAAGVKSMNLK--
-DVQDGLVFKRFQEALFITQRASVKKMALH------RAKRGLQIL----RLPHRQ-FMIGIS--FLVNLLTDTKKLVQINP-DYTV---HNNGSFVLDTS
D--PV---SYY-
>tr|F9VEM4|F9VEM4_LACGL DNA topoisomerase 4 subunit A OS=Lactococcus garvieae (strain Lg2) GN=parC PE=3 SV=1
AQQLIAEEETVVSVTRGGYIKRTSPRSFASSN--V---------DD-QLIFVKAGRTTQHLLMFTSLGNVIYRPVHELSD-----IGEHISQTLNN-ADE
E--FAQVLD---GEN-YMVVTAAGQIKQVELASFK----KSMVYGKLK-KDSIVT---V--DEDVLLISENGYAL------I--VGAKAAGVKAMNLK--
-DVKAAFFVQT-DSWYLLTQRGFIKRVKSE------RANRGLQVL----RLPHTF-AAGSVIQSQILEVTSAVGKVYQTEL-DLKL---ASNGHPLAEDI
R--EAKIK----
>tr|A0A0R2DHX4|A0A0R2DHX4_9LACO DNA topoisomerase (ATP-hydrolyzing) subunit A OS=Lactobacillus floricola DSM 23037 = JCM 16512 GN=FC86_GL000802 PE=4 SV=1
QTALIAEENTRVLISRNGYMKRSSLRSYQSSS--E---------ED-RTILN-ETSTLDHVFIFTNKGHVVYRPVHEIED-----TGHHISQDL-K-EDE
Y--RVFTFN---QGGQFVLATDNGYVKQVKLEDVK----HATTVMKLK-DATIVS---E--NKEVLIITNHAYAL------V--VGPKAVGVKSINLK--
-DVRDVKLLNSASKLGILTQRGAYKQLLLA------RAKRGILIL----RLPHRI-STVMIE-EAKLAIITDKEKIIELIT-NYPI---YSNGSFVLDVK
Q--PQKMSLLE-
>tr|A0A0F4LT67|A0A0F4LT67_9LACO DNA topoisomerase 4 subunit A OS=Lactobacillus mellifer GN=parC PE=3 SV=1
QRVLVSAETVRVLVSHQGYLKRSSLRSYQASA--A---------AD-YPVLD-QVSTREHLYVFTNYGNLIYRPVYELED-----TGAHLSQML-N-ADE
K--GAYIFP---QNGNFVVATSDNYIKQVAFSALL----KATSIIKRH-NSTILG---A--QAEVLGFTQKAYGL------V--LGIKAGGVKFMALK--
-DIAAWCLQTNTKFIGILTQRGAFKKMKLT------RARRGMLTL----HLPHRK-YSFL-L-DDILEVATDKHKLFELKM-DFSA---YSNGSFVINIE
E--IIYALKQN-
>tr|I7JVD6|I7JVD6_9LACO DNA topoisomerase 4 subunit A OS=Lactobacillus hominis DSM 23910 = CRBIP 24.179 GN=parC PE=3 SV=1
EKALMADEDVRVLVSRDGYLKRSSIRSFQSTN--D---------GD-KVIFE-KTSTLSNLYIFTNKGNMIFRPVHELIE-----TGQHLSQEI-G-ADE
E--RVFEVD---QNDNFLLATNDGYIKQVALADLQ----RAITSMKLK-DSKVVR---P--NFEITLITNHAYAI------V--SGAKAAGVKSVNLK--
-DVVNYVLVDAELNVGLITQRGAFKQFELK------RAKRGVLVL----RLPHRQ-ALVEYG-NHELLLTTSSARHITIKT-EFPL---YSNGSFVLDPT
D--PVDLTLGK-
>tr|C2E6F6|C2E6F6_LACJH DNA topoisomerase 4 subunit A OS=Lactobacillus johnsonii ATCC 33200 GN=parC PE=3 SV=1
EKALVADEDVRVLVSKDGYLKRSSLRSFQSTD--D---------GD-KVVFE-KTSTLDNLYIFTNKGNLIYRPVHELIE-----TGQHLSQEI-G-DDE
E--RVFEVN---ANLNFLIATNDGYIKQVTLADLQ----RAITAIKLK-DSKVIR---Q--KEEITLITNQAYAV------I--SGSKAVGVKSVNLK--
-DIVNYVLADPLIKVGIITQRGAFKQLKLN------RAKRGVLVL----RLPHRM-AISSYG-NHILHLNTSSNRHIELNT-EFPL---YSNGSFVLDPM
D--PVSLTLGQ-
>tr|A0A0R1Y001|A0A0R1Y001_9LACO DNA topoisomerase IV, A subunit OS=Lactobacillus pontis DSM 8475 GN=FD34_GL000889 PE=4 SV=1
TKVTVAKEDVMVLVSHAGYIKRSSLRSFKASA--L---------DD-YPLLI-QQTTLAHLFMFTNLGHVIYRPVHEIAD-----TGEHISQTI-G-ADE
E--TAKIFD---LPGTLLMGTSDGQVKQSAFTDYQ----HASVAIKLK-NARLVS---E--NQSLLAISRDGYAV------V--TGIRTAGVRAINLK--
-DMADLALVTDGQRIATITQRGAFKEMPLE------RSRRGELVL----HLPHQA-DFLAYD-TGNLEVITDRPMFQDIAI-DHHL---KSNGTFVIDTD
Q--PVKIRRKQ-
>tr|A0A0R1WPP6|A0A0R1WPP6_9LACO Dna topoisomerase iv, a subunit OS=Lactobacillus oris DSM 4864 GN=FC49_GL000224 PE=4 SV=1
TKVTVANEDVVVLVSHAGYIKRSSIRSFKASS--L---------DD-YPLLI-TQNTLAHLFMFTNRGHVIYRPVHELAD-----TGEHISQTI-G-ANE
E--KAMVFD---LPGSFIFGTSDGQVKQSAYKDYQ----HASMAVKLK-DATVIS---E--NRSLLAISREGYAV------V--TGLRTAGVRAINLK--
-DLADLVLVKDGQRVASITQRGAFKEMPID------RARRGELVL----HLPHKA-DFLAYD-AGTFEVITDRPQFQDVAV-DHHL---KSNGTFVIDTE
Q--PVKIRVKE-
>tr|A0A0R1P3A7|A0A0R1P3A7_9LACO DNA topoisomerase (ATP-hydrolyzing) OS=Lactobacillus frumenti DSM 13145 GN=FD27_GL000826 PE=4 SV=1
TKVTVAKEDVVLLVSHAGYIKRSSLRSFKASS--I---------DD-YPLLI-QQNTLAHLFMFTNLGNVIYRPIHEIAD-----TGEHISQTI-G-ANE
E--KAMVFD---RPGTFLMGTNDGQIKQSSFADYK----HASTGIKLK-DSRLVS---E--NQSLMVVSHEGYAV------V--TGLRTSGVRAINLK--
-DAVDYVIVNEGDDLALVTQRGAFKEMAAS------RARRGELVI----HLPHKV-DFLAFS-TETLEIITDRPAFQDVAV-DHHL---KSNGTFVVDTD
Q--PVKIRHKF-
>tr|A0A0R1XD15|A0A0R1XD15_9LACO DNA topoisomerase IV, A subunit OS=Lactobacillus panis DSM 6035 GN=FD32_GL001102 PE=4 SV=1
TKVTVANEDVVVLVSHAGYIKRSSLRSFKASS--L---------DD-YPLLV-EQTTLAHLFMFTNLGHVIYRPVHELAD-----TGEHISQTI-G-ANE
E--KAMVFD---LPGTLIFATSDGQVKQSAYQDYQ----HASMAIKLK-DAQVVS---E--SRSLLAISREGYAV------V--TGLRTAGVRAINLK--
-DLVDLAIVADGQRIASITQRGAFKEMPVD------RARRGELVL----HLPHRA-DFTAYD-TGYFEVITDRPLFQDISV-DHHL---KSNGTFVIDTE
Q--PVKLRVKQ-
>tr|A0A073JM65|A0A073JM65_LACRE DNA topoisomerase IV subunit A OS=Lactobacillus reuteri GN=LR3_09765 PE=3 SV=1
TKVTVANEDVVVLVSHAGYIKRSSIRSFKASE--A---------DD-YPLLI-QQNTLSHLFMFTNLGHIIYRPIHEIAD-----TGEHISQTI-G-ANE
E--KAMIFD---QPGTIIMGTSDGQVKQTAFNDYK----HASVAIKLR-NAQVVN---E--NCSLLTISRQGYAV------V--TGIRTAGVRAINLK--
-DVADQILVKDGQDIAVITQRGAFKEMPVD------RARRGELVL----RLPHEA-DFLAYD-QGAFEAITNRPAFQDIMA-DHHL---KSNGTFVIDTD
Q--PVKLRLKQ-
>tr|C2ESF7|C2ESF7_9LACO DNA topoisomerase 4 subunit A OS=Lactobacillus vaginalis DSM 5837 = ATCC 49540 GN=parC PE=3 SV=1
TKVTVAKEDVILLVSHAGYIKRSSVRSFKASP--I---------DD-YPILI-QQNTLAHLFMFTNLGNVIYRPVHEITD-----TGEHISQTI-G-ANE
H--KAMVFD---QPGTIIMGTSDGQIKQSAFTDYK----RTTTGIKLK-EARLVS---E--NRSLLVISHEGYAV------V--TGLRTGGVRAINLK--
-DATDYTLVSEGQNLAMITQRGAFKEMASS------RARRGELVI----HIPHKV-DFLAYD-HDVLEIITDRPAFQDVAV-DHHL---KSNGTFVVDTD
Q--PVKLRRKK-
>tr|A0A0R1W1W4|A0A0R1W1W4_9LACO Topoisomerase IV subunit A OS=Lactobacillus suebicus DSM 5007 = KCTC 3549 GN=FD16_GL000675 PE=4 SV=1
TEVLVPDEDVVVLVSHDGYIKRSSTRSYSASD--T---------DD-YPIFL-DKNTLAHLFLFTNKGHLIYRPVYELTD-----TGEHISQTI-G-DDE
Q--KAMSFD-L-SAGTFLMATNDGYIKQTAFKDYL----HPSVYIKLK-ESFVTN---E--DETVLLMSHNGLAL------V--NGARTAGVKSMDLR--
-DVVDLMLCTSDDNIALITTRGAYKEMKAE------RARKGVLIL----RLPHRS-DFITYP-EGALEIITDRPIVQDILT-DHPL---YSNGSFVIDTE
V--PVMLRQKL-
>tr|A0A099YAP6|A0A099YAP6_9LACO DNA topoisomerase 4 subunit A OS=Lactobacillus mucosae GN=parC PE=3 SV=1
TKVTVAKEDVVVLVSKAGYIKRSSLRSFKASN--V---------DD-YPLLI-QESTLAHLFMFTNLGHLIYRPVHELTD-----VGEHISQTI-G-AGE
E--KALIFD---MPGTLLMGTSDGQVKQTEFKEYQ----TATVYMKLK-DAQVVN---E--AQSLLAISHEGYAV------V--AGVRTTGVRAINLH--
-DMVDLQLVDEDQHLAMVTQRGAFKEMAVA------RARRGELVL----HLPHKV-DFLPYD-QGAVEIITDRPLFQDVLI-DHHL---HSNGTFVIDTE
Q--PVKLRIKP-
>tr|A6TJ82|A6TJ82_ALKMQ DNA gyrase subunit A OS=Alkaliphilus metalliredigens (strain QYMF) GN=gyrA PE=3 SV=1
MIDLVDEEDVVITLTHFGYIKRLPIDTYRSQKRGGKGISGVTT-DEDFVEKLTITSTHSPLLFFTNLGKVYKLNVYEIPER-RQAKGTAIVNLLQLSA-E
KIAAVIPVD---NEQYLVMATQKGIIKKTELCQFDN-RKTGLMAINIREDDELISVR-INK-QEIFMITSQGMSIRFKE--VRDMGRTAMGVKGINLA--
-KVVAMEVLED-KDLLVVSENGLGKRTDLSEYRLQTRGGKGIKTYKVS-K-TGNLIGAKIVEH-DEILLMTNEGIVIRLNVKGISKMGRATRGVTLMNTG
EK-IVSIAQIP-
>tr|A0A095XAG3|A0A095XAG3_9FIRM DNA gyrase subunit A OS=Tissierellia bacterium S7-1-4 GN=gyrA PE=3 SV=1
VLNLIADESVVITITERGYIKRVNENTYKAQKRGGKGVKGLTT-VEDVVNDLYTLTTHDEVYFFTNLGKVYSLRAYEIPEG-RTAKGTAIVNLLQISG-E
RITQIIPIK---ERQFMTFVTKNGIIKKTELSQYEN-RQSGLIAINLDEDDDLISVY-TNE-DEFISTTKNGKAIRING--VRPTGRSTRGVKLITLE--
-GVVSSQVVGK-AKLLTITEKGYGKMTSEEEYTVQSRGGKGILTHRIN-E-TGALVTALVVYE-KDLLLISSSGIIIRISAKEIAKSSRATIGVKLMDIG
EK--VSAIQT--
>tr|F4LR80|F4LR80_TEPAE DNA gyrase subunit A OS=Tepidanaerobacter acetatoxydans (strain DSM 21804 / JCM 16047 / Re1) GN=gyrA PE=3 SV=1
IEDLIVEEDIVITQTHFGYVKRQPISAYRSQRRGGRGVTGITT-EEDFVEHIFVGTTHHVVMFFTNKGNVYKLKAYEIPDS-RTARGTAIVNLLPLKP-E
RVNTMITIK---EARYLIFATKNGIVKKTLLSEYAS-RRTGLIAITLKDDDELIGVR-VDR-EEIILGTHNGMSIRFSV--VSSTGRTSQGVKGINLR--
-DVVSMDIVR--HDVLVVTEKGFGKRIDEKEFRCQARGGRGVIIQKIT-D-TGPLAGLRVVGN-DEIMLCTSSGIMIRLLTSEISKMSRNTMGVTLIKLE
DD-LASMAVVT-
>tr|R1CAV0|R1CAV0_9CLOT DNA gyrase subunit A OS=Caldisalinibacter kiritimatiensis GN=gyrA PE=3 SV=1
IEDMIEEQRVAITLTHFGYIKRMPEDTYKLQKRGGKGVIGITT-EEDFVEHLFITSTHDYLLFFTNAGKVYRMKAYEIPER-RQSKGTAIVNLLQLEP-E
KITAVIPIN---KKSYLVLLTKHGTIKKTQLDKFDT-RKNGLIAINLKEDDELISVK-TTG-NDLIIVTAHGMAIRFNE--VREMGRTAMGVKAITLN--
-GIVDMSLVEE-DDLLVVSEKGYGKRTSLDEYRTQTRAGKGIKTYNIK-S-TGNISAAKVVKD-DEVMLISQAGSIIRLRVSGVSKMGRSTSGVTLMRLD
ED-VVSIAKVV-
>tr|A0A096BH59|A0A096BH59_9CLOT DNA gyrase subunit A OS=Caloranaerobacter azorensis H53214 GN=gyrA PE=3 SV=1
IEDMIKEEKVVITLTHFGYIKRLPEDTYKAQRRGGKGITGLTT-EEDFVEDIFVTSTHDNILFFTNKGKVYKLRAFEIPEAKRQAKGTAIINLLNLDI-E
KITAVIPIK----EDYLVFATKKGLIKKTGLNEFDN-RKNGLIAINLREEDELIEVR-TNG-DELILVTAHGMSIRFSE--VRNMGRSAMGVKAITLN--
-DLVAMDLIKEDNDLLVITEKGYGKRTQISEYRSQSRGGKGIKTYNVR-E-TGNIVGAKVVSN-DEVMLISVSGTIIRLKVSDISQMGRSTQGVTLMKVS
N-RVVSIAKVA-
>tr|K0AWF9|K0AWF9_CLOA9 DNA gyrase subunit A OS=Clostridium acidurici (strain ATCC 7906 / DSM 604 / KCTC 5404 / 9a) GN=gyrA PE=3 SV=1
IEDMIQEENVAITLTHFGYIKRLPEDTYKTQKRGGRGVAGLTT-EEDFVEHLFITSTHDNLLFFTNQGKVYTMKAYEIPEAKRQARGMAIINLLQLNP-E
KITAVIPIR----DNYLILVTKKGITKKLRLNELQN-RKNGLIAISLKEEDELIGVR-TEG-DNVILVTSNGMSITFNE--VRDMGRTAMGVKAITLN--
-GLVGMDLVKPNKELLVISEFGYGKRTSLDEYRIQSRGGKGIKTYNIK-DITGKIISAGVVED-DDILIVSLGGTIIRLNVSDISQMGRSTQGVRLMKMA
D-KVVSVAKVL-
>tr|A0A0D8I8L8|A0A0D8I8L8_9CLOT DNA gyrase subunit A OS=Clostridium aceticum GN=gyrA1 PE=3 SV=1
MEDMIDEEDVVITLTHFGYIKRLPIDTYKSQKRGGKGISAVTT-EEDFVEKLIITSTHDYLLFFTNKGKAYKLNVYEIPEK-RQAKGTAIVNLLQLAP-E
QIAATIPVG---GSKYLIMATKKGIIKKTQLNQFEN-RRSGLIAISIREDDELISVR-TDT-QEVIMITAKGMAIRFKE--VRDMGRGAMGVKGITLS--
-EIVGMDIIED-KDLLVVSYKGFGKRTDLKQYRLQSRGGKGIKTYNTT-E-TGLLVGAKIVTK-DEILLISNDGIVIRLNVDNISKMGRNTKGVTLMRTD
NK-IVSIAQIP-
>tr|A0A0B7MKF4|A0A0B7MKF4_9FIRM DNA gyrase subunit A OS=Syntrophaceticus schinkii GN=gyrA PE=3 SV=1
EEDIIPEEDVVVTLTRRGYIKRIPVATYRGQHRGGRGITALTT-DEDLVEHFFVASTHSFILFFTSRGKVYRVKIYEIPEGSRQAKGTALVNLIPLDG-E
LVTAVIPLR----DKYLFMATRQGIVKKGVLSDYDS-RKDGIIALGLRPNDELIGVR-TEG-CDITLVTRDGKAICFNE--VRPMGRTATGVIGIRLD--
DQVVGMERF-I-GQLLVVTEKGYGKRTDIKEYRLQKRGGKGIITLRVS-D-NGYLVGVRVVNN-DEILLISSDDIIIRIPVKEIALQGRNTQGVRLMRFD
G-RVVAVAKVP-
>tr|A8MEA6|A8MEA6_ALKOO DNA gyrase subunit A OS=Alkaliphilus oremlandii (strain OhILAs) GN=gyrA PE=3 SV=1
IEDMITEEEVVITLTHFGYIKRLPADTYKSQKRGGKGIAALTT-EEDFVENLITSSSHDYLLFFTNFGRVYKLNVYEIPER-RQAKGTAIVNLIPLSP-E
TVAATIPVG---DSKYLVLATKNGIIKKTQLSQFES-RKSGLIAISIREDDELIKVK-TDE-SEIILITAQGMSIRFKE--VRDMGRSAMGVKGINLS--
-KVVSMEIVEE-KDLLVISEKGFGKRTDTSEYRLQTRGGKGIKTYNVT-G-TGPLVGAKIVTE-DEVLLINNYGTVIRLNVSNISKLGRNTKGVTLMRME
DQ-IITIALMA-
>tr|A0A0K2SFJ2|A0A0K2SFJ2_9FIRM DNA gyrase subunit A OS=Limnochorda pilosa GN=gyrA PE=3 SV=1
TEDLIAEQQVVVTLTRLGYVKRLPVDTYRAQRRGGRGITAVHA-EGDFVERLFVASTHSYVLFFTNRGRVYRVRAHEIPES-RTARGTAAVNVVPLQP-E
QVTATIAIR---EGHHLVMVTRKGTVKKTVLSEFDT--RNGIICITLDEDDDLVDVL-TDG-RELVLVTAHGQAIRFPE--VRPMGRAARGVRGIRLE--
-GVVSAGEVQ--SELLVVTANGYGKRTALDQYRRTARGGKGIRTLNLT-D-TGEVIDARVVRE-EEAMLISSRGVMIRISVGEVSVQGRITQGVRLMRLA
GE-VVAAGTLI-
>tr|B1C9C4|B1C9C4_9FIRM DNA gyrase subunit A OS=Anaerofustis stercorihominis DSM 17244 GN=gyrA PE=3 SV=1
MEDLIEEEDIVVTITHVGYVKRLPASTYKTQKRGGKGVTALST-ENDFVKHLFFTTTHHYIMFFTNKGKVYRLKGYEIPDS-RIAKGTAIVNLLALDPGE
KITAVIPIK---DDEYLVMATRNGVFKKTSLTEYDS-RKNGIVAINLAEDDELIGVS-TDG-QNIILGTHKGLAIKFNE--VRAIGRVSKGVKGISLK--
-DLIGMDIAT--AYVLSVTEKGYGKITKTNLYPTQGRAGKGVLNYKLT-K-TGALSGMCVIEE-DDIMVISIDGTVIRIDTSGISQMGRSTSGVKVMTLD
EDNISTIAKVP-
>tr|Q0W7S4|Q0W7S4_METAR DNA gyrase subunit A OS=Methanocella arvoryzae (strain DSM 22066 / NBRC 105507 / MRE50) GN=gyrA PE=3 SV=1
DEDLIPVENVVVTISNTGYIKRMPVDTYRTQRRGGVGIVGMET-EEDFVVDLFVASTHDNILFFSNKGKVYSLKVYEIPPASRQARGKAIINLINIEP-E
AINAMIPIK----QHFLVMCTREGTIKKTALSAFQN-RSTGIIAIGLESGDELISVK-TNG-QEVLIATRNGKCNRFSE--VRTMGRPAMGVIGIRLT--
DKVIAMEIVSP-QSVLTICENGFGKRTPIEEYTAHHRGGQGMINIKTT-L-NGAVVAVISVMD-DQIVIASKEGMMTRMNVTDIPEIGRNTQGVRVMKMR
E-SVVAVARLV-
>tr|G3YX41|G3YX41_9LACO DNA topoisomerase 4 subunit A OS=Lactobacillus sp. 7_1_47FAA GN=parC PE=3 SV=1
EKALLSEEDVRVLVSANGYLKRSSLRSYQSTD--S---------GD-EVIFD-KTSTLSNLYIFTNKGNLIYRPVYELVD-----TGQHLSQEI-V-TDE
R--SVFDIN---SDLTFLITTNDGYIKQVALSDLQ----RAIMVIKLK-HSNVLM---K--DNEILLVTNNAYAL------V--VGPRAAGVKSINLKD-
-DVVSAITFDPSLKLGIVTQRGAFKQLQVD------RAKRGSMIL----RLPHRV-AALIYT-NHDINIKTSSDRTIKIRT-DYPV---YSNGSFVVDTI
D--PVALKLGM-
>tr|A0A0M0L5H4|A0A0M0L5H4_9BACI DNA gyrase subunit A OS=Bacillus koreensis GN=gyrA PE=3 SV=1
DEDLIPRQDIVITLTHNGYIKRLPVSTYRSQKRGGRGIQGMNM-ENDFVEQLLTTSTHDTILYFTNKGKVYRTKGYEIPEFSRTAKGLPIINLLEVDK-E
WVNAIIPVE---DDAYLFFTTKQGVSKRTPLSSFEN-RTSGLIALGLREEDELISVK-TDG-KEILIGTQNGMLIRFPE--VRSMGRTATGVKGITLA--
DDVVGMEISDDESDILIVTRNGYGKRTKTSEYRIQSRGGKGLRTCNVT-EKNGKIVSLKTVTE-EDIMLITVSGVLIRVATKDVSQMGRNTQGVKLIRLG
-EFVSTVAKVE-
>tr|A0A0G0N8B3|A0A0G0N8B3_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWF2_38_76 GN=gyrA PE=3 SV=1
VEDLIPDDENVLVLTSGGYIKRTDPGEYRAQRRGG-G--VLN--ED-FITIFLTASNHSDLLFFTDKGKAYQIKMYDIPEK-RATRGKSIMNFL-SAD-E
R--SVLAMPN--QKSSLLMITKMGVVKKVSTDSFKD-R-SGIIAIKLQ--DELMT---V---DSIILITAGGQSV------AREMGRAAAGVRAVKLKK-
-AVVGADVIKKESKLLVMSEHGFGKMTKI-EYK-QKRGGSGIKTA---TAKTGQM-VGKVIT--EELIAISKNAQVIRINI-EVPV-GR---GVRIMRLR
D-SIASLTCL--
>tr|A0A0G1X3A5|A0A0G1X3A5_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWF2_52_12 GN=gyrA PE=3 SV=1
DEDLVPEKESMLTLSSGGYVKRTDPSEYRSQRRGG-G--VLN--ED-FVTIFLTTNTHSDLLFFSDRGKAYQTKMYEIPER-RATRGKSIMNFL-PSD-E
R--SVLAFPT--SKLSLVMVTTKGVIKKVSAESFKD-R-SGLIALKLS--DFLHS---V---DTVILSTTRGQAI------TREMGRAAGGVRAVLLKG-
-EVVSADIVKKDVAYLSLSEKGYGKRTPV-DYK-QKRGGSGIKTM---TAKTGNI-ISRVVA--AELVAISKHGQVIRTAV-EIPV-RR---GVRIMKLR
G-SLASLTFL--
>tr|A0A0G1BUG5|A0A0G1BUG5_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWB1_42_9 GN=gyrA PE=3 SV=1
LEDLVPEKEDVLVLTAGGYIKRTDPSEYRAQRRGG-G--ILN--ED-FVTTLLTANTHDDLLFFTNRGKAYQIKMYDVPEK-RATRGKSIMNFL-STD-E
K--SILPMP-----FSLLMVTKDGDVKKVSADSFRD-R-SGIIAIKLG--DLLLS---VD---QMILTAQSGQSI------VREMGRAAGGIRGMKLKK-
-GIVGADCIPVEGSLLVMTDTGHGKRTLL-EFK-QKRGGSGVKAV---TKKTGPM-VSKVID-QQEIIAISKQGQIIRTNI-EIPT-GR---GVRIMKLK
E-GIASLTCL--
>tr|A0A0R1UJE8|A0A0R1UJE8_9LACO DNA topoisomerase IV, A subunit OS=Lactobacillus equigenerosi DSM 18793 = JCM 14505 GN=FC21_GL000145 PE=4 SV=1
TKITVPNEDVMLLISHAGYIKRSSLRSYKASD--A---------DD-YPLVT-METTLSHVWMFTNHGNVIYRPVHEIAD-----TGEHLSQTI-G-ADE
E--AAYVFD---QPGSIIMATSDGQIKQSAFADFK----RPSVGMKLK-AARVVA---Q--D-SIVAISKEGYGL------L--TGLRTAGVRAINLKD-
-QVNI---ALVADHLALITQRGAFKEMRVS------RARRGNLVL----HIPHQA-DFIGHP-TGTLEVITNRPMFQDVQV-DHHI---KSNGTFVVDVD
Q--PVKLHFKD-
>tr|H4GI18|H4GI18_9LACO DNA topoisomerase 4 subunit A OS=Lactobacillus gastricus PS3 GN=parC PE=3 SV=1
TKITVANEEVMVLVSHAGYIKRSSMRSFNASD--F---------DD-YPLLV-TKSTLSHLFMFTNQGNVIYRPVHEVMD-----TGEHISQTI-G-ADE
E--TTLVVD---QAGSILMASSDGQVKQSAFADFK----RPTLAFKLK-DARVVA---D--KQSLVAISKAGYGL------L--TGLRTSGVRAINLK--
-DLVDLALVEESDHLALITQRGAFKEMLAS------RARRGNLVL----HLPHEA-DFIGHA-QGALEIITSRPVFQDVLV-DHHL---KSNGTFVIDTD
Q--PVLIRKKI-
>tr|E0P0I5|E0P0I5_9FIRM DNA gyrase subunit A OS=Selenomonas sp. oral taxon 149 str. 67H29BP GN=gyrA PE=3 SV=1
IKDLIAEEDVVVTLTLNNYIKRIPLDTYRRQRRGGVGVRGMGT-ETDIVSDLLITTTHHDILFFTNRGRAFVLKSYEIPESGRQAKGTAIVNLLAVEN-E
RITAVIQVK----DRYLFLGTKHGVVKKTPLSEFGN-RKNGLRAVNLDEDDELIGVK-TDG-NRIMLGTRGGKAITFPE--VRSMGRVARGVRGITLA--
-GVVAMDVLRSDSEVLTVTEGGYGKRTTASEYRTQTRGGKGLINMKVT-E-TGPVVGIRVVRN-QELMLITTEGIVIRTSVDEISLISRNTQGVKLMTIA
S-RVASMATMN-
>tr|C9KLW4|C9KLW4_9FIRM DNA gyrase subunit A OS=Mitsuokella multacida DSM 20544 GN=gyrA PE=3 SV=1
VEDLIAEEDVVITLTHNNYIKRMALDTYRRQNRGGKGIKGMPT-EKDFVENLLITTTHHTILFFTNRGRVYHLKAYEIAEASRAAKGTAIINLLQLEK-E
KITAVIQVK----DAYLFMATKKGIVKKTSLVEFKN-HKGGLNAINLDDDDELIGVK-TDG-RDMILGTKWGMAIVFGE--VRAMGRAARGVKGISLN--
-GVIGMDTLSPNAEVLTVTAEGYGKRTETSEYRAQNRGGKGLINLKVT-E-TGDVIGLRVVHD-QELMLITTEGIVIRTNISDISVISRNTQGVKLMSTG
N-IVASMAVMD-
>tr|A0A0B2JMZ4|A0A0B2JMZ4_9FIRM DNA gyrase subunit A OS=Anaerovibrio lipolyticus GN=gyrA PE=3 SV=1
IEDMIADDDVVISITHRNYIKRIKLDTYRRQNRGGTGVNGMPT-EDDFVENLLITTNHHTILFYTNKGRVYYLKAYQIAEASRTAKGTALINLLKLDK-E
KVSAVIQVR----DKYLFMATKMGVVKRVSLSDFNT-RKIGVIAISLQEDDELIGVK-TNG-QKIMLGTKNGMAIAFEE--VRVMGRVARGVKGIRLT--
-GVVAMDSLKEDADVLTVTECGLGKRTTIDQYTVQHRGGKGLINLKVT-E-TGKVIGMAVVQD-HELLLITEGGVVLRTSISGISQIGRNTQGVIIMKPS
G-KVSSMATLL-
>tr|C9LYV0|C9LYV0_SELS3 DNA gyrase subunit A OS=Selenomonas sputigena (strain ATCC 35185 / DSM 20758 / VPI D19B-28) GN=gyrA PE=3 SV=1
VEDLIAQEDVVITLTHNNYIKRMPLDTYRRQKRGGVGVTGMGT-EADFVENILVTTTHHTILFFTNRGRVYCLKAYEINEASRQAKGTAIINLLQLES-E
KITAVIQVK----ERYLFMATKKGIVKKTSLSEFQS-RRGGLNAINLDEDDDLIGVK-TDG-KHVILGTAGGMAVAFAE--VRSMGRTARGVKGINLK--
-GVVGMDNLARNAEVLTITAEGYGKRTATSEYRLQTRGGKGLINMKVT-E-TGAVIGLKVVRG-QELILITTDGIVIRTKVDEISVISRNTQGVKVVRLG
G-KAASFAAME-
>tr|U2UKI9|U2UKI9_9FIRM DNA gyrase subunit A OS=Mitsuokella sp. oral taxon 131 str. W9106 GN=gyrA PE=3 SV=1
VEDLIAEEDVVVTMTHNNYIKRIPLDTYRRQNRGGKGVKGMGT-ETDFVENMLITTTHHTILFFTNRGRVYHLKAYEIAEASRAAKGTAIINLLPLQA-E
SITAIIQVK----DNYLFMATKKGVVKKTSLIEFKN-HKGGLNAIHLDDDDELIGVR-TNG-HDVILGTKWGMAILFPE--VRAIGRQGRGVRGIRLS--
-GVIAMDTLMPNADVLTVTAEGYGKRTQRDEYRTQTRGGKGIINLKVT-D-TGDVVGLRVVRD-QELMLITTEGIVIRTNIGDISRISRNTQGVKLMTTA
G-TVASMAVMD-
>tr|I0GLV4|I0GLV4_SELRL DNA gyrase subunit A OS=Selenomonas ruminantium subsp. lactilytica (strain NBRC 103574 / TAM6421) GN=gyrA PE=3 SV=1
VEDLIAEEDVVITLTHNNYIKRMPLDTYRRQNRGGKGIKGMGT-ETDFVENLLITTTHHTILFFTTRGRVYSLKAYEIAESSRTAKGTAIINLLQLDQ-E
KITAVIQVK----DRYLFMATRKGIVKKTSLSEFSN-RKNGLNAINLDDDDDLMGVK-TDG-SYLMLGTKLGKAIAFSE--VRAMGRTARGVKGITLS--
-GVVGMDILVRNAEVLTVTECGYGKRTSTDEYRAQTRGGKGLINMKVT-E-TGYVVGIKVVRE-HELMLITTDGIVIRTNVNDISVISRNTQGVKLMTTA
N-KVASMATLE-
>tr|R5I455|R5I455_9BACT DNA gyrase subunit A OS=Alistipes sp. CAG:831 GN=gyrA PE=3 SV=1
PEDFYADEDVVITISHSGYIKRTPLTEYRLQNRGGVGSKGSTT-DEDFIEHIYVANTHSTMLFFTDKGKCYWLKVYEIPEGTKASKGRAIQNVISIEADD
HVCAYLNVGN--NSHYIVMATKRGVVKKTLLEAYSR-RQKGVNAITIKDGDGLLEAVLTDGNNEILLAARKGKCVRFH---ARSIGRTASGVRGISIE--
-DVIGMVCAARQGNIMVVSANGYGKRSLLE-YRVTSRGAKGVKTLNITE-KTGELIAIKMVT-ENDLMIINKSGITIRVPVSDIRVAGRATQGVRLINLR
-GTIAAVCVVN-
>tr|A0A0F7GBS4|A0A0F7GBS4_9CHLR DNA gyrase subunit A OS=Dehalogenimonas sp. WBC-2 GN=gyrA PE=3 SV=1
EEDLIPHQSMVVTLTERGFIKRVPTEVYRLQHRAGRGKSIIKT-EEDAVRFMMVADTHDSVLLFTNRGKIFSIRCHEIPCLLRTAKGIAIINLV-PAENE
KITAMLALS---DDISLIMATASGEVKRTLVTDFAAVRSSGLIAMDLPKSDELIGAV-SKDEDNIILITHSGQSIHFPV--LRTSQRASGGVRGVTLE--
-DVVGLDVM--NNFVLVVTEHGYGKLTPVEEYPLQHRAGSGVLTF--VK--TGKVVAGRVVDREHQVMIATAEGVVIRTPVGGIIVMGRSTQGVIVIRPD
-NRVVTFATMI-
>tr|K1Y4V5|K1Y4V5_9BACT DNA gyrase subunit A OS=uncultured bacterium (gcode 4) GN=gyrA PE=3 SV=1
PEDFYPDEDVVITISHLGYIKRTPLAEFRIQNRGGVGAKGSTT-DEDFIQHIYVANMHSTMLFFTQKGRCFWLKVYEIPEGSKASKGRAIQNVLNIGQDD
KVCAYINVRN--NNNFIVLATKKGTVKKTSLEAYSR-RVNGVNAITIRENDELLEAVLTNGNSEILLAARNGKCVRFN---VRAIGRTASGVRGINIGD-
-DVIGMICVDYNKHILVVSENGYGKRSNLDDYRVTNRGAKGVKTINITE-KTGSLIAIKDVT-ENDLMIINKSGITIRVAASDIRVVGRATQGVRLINIR
-GMIAAVCRVN-
>tr|G4L3L6|G4L3L6_TETHN DNA gyrase subunit A OS=Tetragenococcus halophilus (strain DSM 20338 / JCM 20259 / NCIMB 9735 / NBRC 12172) GN=gyrA PE=3 SV=1
DEDLIEEEEIVVTLTNNGYIKRAANSEFRTQNRGGRGVQGMGI-DQDFVTTLVSCSTHDNLLFFTNAGKVYKAKGYEVPEYGRTAKGIPVINFLGV-NNE
RIQTIIALP--EERKYLFFTTKYGVVKRTSVESFKN-RSNGLIAIGLKEDDELVNVL-TSG-DVVIIGTHNGYSVTFKE--VRDMGRTASGVRGIRLR--
-EVIGASVIKEDDEVLVITEKGYGKRTSEDQYPVKGRGGKGIKTANIT-E-NGPLAGLTTVSN-EDVMLITDRGVIIRFHVDDISQTSRATLGVRLMKME
D-KVVTMTTVD-
>tr|V6Q9G2|V6Q9G2_9ENTE DNA gyrase subunit A OS=Vagococcus lutrae LBD1 GN=gyrA PE=3 SV=1
DEDLIEEEDSVITLTHNGYIKRLPSSEFRTQKRGGRGVQGMGM-DDDFIENLVSCSTHDTLLFFTNTGKVYRAKGYEIPEYGRTAKGIPIINLLGI-DNE
KIQSVISVE--KENSYLFFTTKHGTVKRTTTEAFAN-RSNGLIAIGLRDGDEVMNVT-TNG-QIIIIGTHLGYSVTFKE--VRDMGRTAAGVRGVRLR--
-GVVGMSTLTENNEVLILTENGYGKRTDSSEYPVKGRGGKGIKTANIT-E-NGPLVALTTVED-EDVLVITDQGVIIRFDVDSVSQTGRATQGVRLIRLE
G-KVATMAIIE-
>tr|R2ST25|R2ST25_9ENTE DNA gyrase subunit A OS=Enterococcus pallens ATCC BAA-351 GN=gyrA PE=3 SV=1
DEDLIEEEDIVITLTNNGYIKRVVSSEFRAQRRGGRGVQGMGI-DDDFVKNLISCSTHDTLLFFTNTGRVYRAKGYEIPEYGRTAKGIPIINLLGI-DSE
TIQAVIAVT--SDGQFLFFVTKNGIVKRTTVTAFSN-RSNGLIAIGLKENDELVNVL-TEG-ETIILGTHNGYSVTFAE--VRDMGRTASGVRGVRLR--
-DVIGSAVLKDDQEVLVITEKGYGKRTKAADYPVKGRGGKGIKTANIT-D-NGQLAGLATVND-EDILLITDKGVIIRFNVASVSQTGRATLGVRLMKME
N-KVVTMAVVE-
>tr|A0LQS2|A0LQS2_ACIC1 DNA gyrase subunit A OS=Acidothermus cellulolyticus (strain ATCC 43068 / 11B) GN=gyrA PE=3 SV=1
IEDLIAEEDVVVTITRGGYAKRTKTSLYRSQRRGGKGIQGA-QRQDDVVEHFFVTTTHHWLLFFTDKGRVYRLKAYEIPEAARSARGQHVANLLAFQPDE
KIAQVLALR---AP-YLVLATRSGLVKKTALREFDS-RTGGIIAINLRD-DVVIGAR--SPDDELLLVSRKAQAIRFRE--LRPMGRATSGVIGMRFH-D
-DLLAMMVVRPQAYVFVATTKGYAKRTPIEEYPLQGRGGYGVITAKIT-AERGDLVGALMVDE-DEVLAITVLGGVIRTRVSEVRP-SRATMGVRLMDLA
-NALVAITRNA-
>tr|S0KDY4|S0KDY4_9ENTE DNA gyrase subunit A OS=Enterococcus columbae DSM 7374 = ATCC 51263 GN=gyrA PE=3 SV=1
DEDLIEEEEVVLTLTNNGYIKRVAKSEFRAQRRGGRGVQGMGV-DEDFVKTLVSSSTHDTLLFFTNQGKVYKAKGYEIPEYGRTAKGIPVINLLGI-DNE
KIQAIIPVS--EEGKYLFFTTKYGVVKRTEVTAFAN-RSNGLIAIGLKDGDELVNIL-THG-DTIIIGTHDGYSVTFAE--VRDMGRTAAGVRGIKLR--
-DVVGSAVMKENQEVLVITENGYGKRTAASEYPIKGRGGKGIKTANIT-E-NGPLAGLTTVDS-EDILVITDKGVIIRFNVDSVSQTGRATLGVRLMKME
D-KVVTMATVE-
>tr|Q939I1|Q939I1_STREE DNA topoisomerase 4 subunit A OS=Streptococcus pneumoniae GN=parC PE=3 SV=1
TASLIAEEDTYVSVTKAGYIKRTSPRSFAASA--I---------DD-RLIFG-QSKTIQHLLMFTSLGNVIYPPIHELAD-----IGEHLSQTITN-ENE
E--YVEVLD---ATT-YFAATRLGQIKRVERKEFS----KSVKYAKLK-TDQIVA---K---DDVLLISQNGYAL------V--VGAKAAGVKAMNLK--
-DLQSGFICNT-SSFYLLTQRGSLKRVSVE------RAKRGLQVL----RLPHRF-LAGAVSVDQTLLVQSNKGTIYENRL-DLNL---TSNGSFISDTI
D--VFDAYLQE-
>tr|F3LBG9|F3LBG9_STRPO DNA topoisomerase 4 subunit A OS=Streptococcus porcinus str. Jelinkova 176 GN=parC PE=3 SV=1
TASLIVEEETFVSLTQGGYIKRTSPRSFNAST--I---------DD-RLIFV-TNKTTQHLLIFTDLGNVIYRPVHELQD-----VGEHLSQTITN-GEE
K--YAELVD---VTY--YSVTQLGQIKRFARAELA----KSLKYAKLK-QDRIIA---L---EDIMLISHQGYAL------V--QGLKTAGVKAMNLK--
-DITSAFLAYT-DSFFVLTQRGSLKRVATE------RANRGLLVL----RLPHRF-LAGAVKNSIKLIVTSKTGQEYLVNL-NYSL---TSNGTFISDSI
D--VLSVRFD--
>tr|A0A0G0YHB7|A0A0G0YHB7_9BACT DNA gyrase subunit A OS=candidate division CPR2 bacterium GW2011_GWC1_41_48 GN=gyrA PE=3 SV=1
EEDLVANETVIVALTKGNYIKRILASTFRQQQRGG-G--MMQ--ED-IVEHMILTHNHDEIMFFTNKGRVFRTKVYEIPMS-RIAKGSPIVNFI-QAE-E
I--SVITVS--TDAKYLFFATKFGVIKKVAIEQFEN-R-NGLIALNLD--DALCW---TD---EIIMATKSGMAN------VRPMGRGARGVRGMKMKG-
-TIMGTDVVVKGQQMMVIMENGYGKRTDV-EFA-HRRGGVGIKAA---TPKTGPV-DVRIIE-KEDLVIVSKQGVVIRLPL-QVNK-GR---GVRVMRLN
--KVSSVTLVT-
>tr|A0A0G0NAV7|A0A0G0NAV7_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWA2_39_18 GN=gyrA PE=3 SV=1
EEDLAPEEEAIVILTRGGYIKRLSPDTWKTQKRGG-G--MVE--ED-VVEKFLAVNTHDHVSFFTNKGRVFQIRAFEIPES-RTSRGKALVNLL-NGE-E
T--AAVSLR--KSGKFFVMMTQNGIIKRTSADEFSN-R-NGLISITLD--DLLKW---SD---EIICVSEKGQAI------VRTMGRSAKGVRGMKLRS-
-QVVSMDVLTSSRHLLVVSENGFGKRTEL-SYK-QKRGGIGIKTA---TQKTGNV-SAIILQ--EECIAISQKGQVVRTNL-TISV-GR---GVRLMRLS
--KVASVTFI--
>tr|A0A0G0YBJ0|A0A0G0YBJ0_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWC2_42_13 GN=gyrA PE=3 SV=1
VEDVIPEEEAILVITKGGYIKRTSPEIYRAQKRGG-G--ILM--ED-MVDDFLTVGTHDNILFFTDRGKVYQLKAYEVPQQ-RQSRGKSINNFI-SAD-E
K--SVLALP--KP--VLVLVTKNGVIKKTDASNFEE-R-TGIIALKLQ--DVLKW---A---DYIILSTSQGQAI------ARKMGRTAAGVRAIRLKK-
-ELIGADVVGQQALLLVVSSKGYGKKSKI-DYR-QRRGGSGIKTA---TAKTGFV-SAKVID-SEEVIAISKKGQVLRTAL-SIPT-GR---GVRIMKLT
G-SIASLTCL--
>tr|F2HLR1|F2HLR1_LACLV DNA topoisomerase 4 subunit A OS=Lactococcus lactis subsp. lactis (strain CV56) GN=parC PE=3 SV=1
ASELIVAEDTVVSVTRSGYIKRTSPRSFASSA--L---------DD-ELLYY-ANKTTQHLLLFTNLGNVIYRPIHELSD-----IGEHLSQSLSN-SDE
K--FVQIVD---E-N-LLVVTRNGQIKQIERESFS----KSTPYAKLK-DDEIVL---Q---ADLMLISENGYAL------V--LGARAAGVKAMNLK--
-DIKSAFFVNS-NSWYLLTQRAFIKRVKTD------RANRGLQVL----RLNHTF-AAGLINKEQVLEVISETGKKYDINL-DLSL---TSNGHPIADDL
K--SVKNKIKK-
>tr|F3UXK4|F3UXK4_STRSA DNA topoisomerase 4 subunit A OS=Streptococcus sanguinis SK49 GN=parC PE=3 SV=1
TASLIVEEETYVSVTRSGYIKRTSPRSFSAST--L---------DD-RLIFV-SPKTTQHLLIFTSLGNVIYRPVHELSD-----IGEHLSQTISN-DKE
E--YTELLD----GT-YFAATKLGQIKRVERKEFS----KSLKFAKLK-DDQVIA---K---DDVMLVTKNGYAL------V--IGAKAAGVKAINLK--
-DLAAAFIANT-DSLYLLTQRGSLKRMAVA------RANRGLQVL----RLPHRF-AAGPVY-EQILQVLSNKGTAYEINL-DLSL---TSNGSFISDTI
D--VFSAYIK--
>tr|E3CDX2|E3CDX2_STRPA DNA topoisomerase 4 subunit A OS=Streptococcus parasanguinis F0405 GN=parC PE=3 SV=1
TASLIVEEETFVSVTRAGYIKRTSPRSFNAST--V---------DD-ELIFV-EPKTTQHLLLFTNFGNAIYRPIHELTD-----IGEHLSQTLTN-EEE
E--FAEIVD----VT-YFAATQQGQIKRFERKELS----KSTKYAKLK-DDRIVA---V---EDIMIITKNGYGL------V--VGAKAAGVKAINLK--
-DVAAAFKSTT-PSMYILTQRGSLKRMLQD------RAKRGLQVL----RLPHRF-KAGPVFVDQILQITSTTGQVTEIDL-QLSI---TSNGSFVNDTI
D--VFSATIK--
>tr|A0A0B7IQ23|A0A0B7IQ23_9FLAO DNA gyrase subunit A OS=Capnocytophaga canimorsus GN=gyrA PE=3 SV=1
VEDMIPDETMVITITHAGYIKRTSLNEYKTQNRGGVGQKASNT-DQDFLEHLFVSSNHQYMLFFTQKGKCFWMRVYEIPEGTKTSKGRAIQNLINIEQDD
KVKAFISVKK--NNNFLIMATKQGIVKKTLLEEYSR-RQNGINAITIKDGDELLEAKLTSGKSQLMLAVKSGRAIRFE---VRAVGRNSQGVRGIDLDET
-DVVGMIAIENEETVLVVSENGYGKRSYIDVYRITNRGGKGVKTISITE-KTGNLVAIKSVL-GEDLMIINKSGIAIRLPIDDLRIMGRATQGVRLINIK
-NSIAAVAKVM-
>tr|I9P9F2|I9P9F2_9FLAO DNA gyrase subunit A OS=Capnocytophaga sp. oral taxon 412 str. F0487 GN=gyrA PE=3 SV=1
VEDMIPDDKMVITISHAGYIKRTQLSEYKTQSRGGVGQKASTT-DQDFLEHLFVSSNHQYLLFFTQKGKCFWMRVYEIPEGSKTAKGRAIQNLINIESDD
KIKAFVSVQK--SNNYLIMATKKGIVKKTLLKEYSR-RQNGINAITIKEGDELIEAKLTSGSSQLMLAVKSGRAIRFA---VRSVGRNSQGVRGIDLDE-
-DVVGMIAIEN--TVLVVSENGYGKRSYIDVYRITNRGGKGVKTISITE-KTGQLVAIKSVL-GEDLMIINKSGIAIRLSIDTLRILGRATQGVKLINIK
-KSIAAVTKVM-
>tr|A0A0R2JM96|A0A0R2JM96_9LACO DNA gyrase subunit A OS=Lactobacillus lindneri DSM 20690 = JCM 11027 GN=IV52_GL001407 PE=4 SV=1
DEDLIEDEHVTITLTHNGYIKRLPTDEFKTQNRGGRGIKGMGV-KDDFIEHLLTGSTHDLLLFFTNSGKVYSMKAYEVPEYGRSAKGIPIVNLIHL-GNE
KIQTVLDIS--NDDKYLFFTTKLGTVKRTPLNEFVN-RNNGLKSINLRDQDEVINVS-VDD-QNMIIGTHLGYAVSFKV--VRTMGRSATGVRGVRLR--
-DVIGAAILAPDSDVFVISEKGYGKRTPADQYAIKGRGGKGIKTSNIS-E-NGPLVGLGVIND-EDIMLITDQGVMIRFAAGNVSETGRATLGVHLIRVD
G-KVATMAIVQ-
>tr|W9EEN3|W9EEN3_9LACO DNA gyrase subunit A OS=Lactobacillus florum 8D GN=gyrA PE=3 SV=1
DEDLIEDKNVTITLTHNGYVKRITTDDFKAQNRGGRGIKGMGI-KDDFIEHLLTSSTHDSLLFFTNKGKVYRLKAYEVPEYGRSAKGLPIVNLLHL-DHE
KIQTILNVA--NQPDQLFFTTKMGTVKRTALAEFVN-RNNGLKAINLREHDEVIKVL-VKS-QNMILATRQGYAVSFQV--VRLMGRSATGVRGVRLR--
-NVIGADRLIPGQQVFVISENGFGKQTPVAQYPIKGRGGKGIKTAQIK-E-NGPLVGMNVVAD-EDVMLITTQGVLIRMAIADVSQTGRATLGVHLIRLD
G-KVATMTIVA-
>tr|A0A0R2BXE3|A0A0R2BXE3_LACSN DNA gyrase subunit A OS=Lactobacillus sanfranciscensis DSM 20451 GN=FD36_GL001031 PE=4 SV=1
DEDLIEDKNVTITLTHNGYIKRIPTDDFKTQNRGGRGIKGMGV-KDDFIEHLINGSTHDLLLFFTNAGKVYSMKVYEVPEYGRSAKGLPIVNLINL-GKE
KIQTVLRVD--GEHKYLFFTTKLGTVKRTPIDEFTN-RNNGLKAINLHDDDELIKVS-VDG-QNMIIGTHLGYAVSFKV--VRSMGRSASGVRGVRLR--
-DVIGAAILTPGSDVFVISENGYGKRTPVNQYPIKGRGGKGIKTSNVT-E-NGPLVGLGVVND-EDIMLITDQGVMIRFAAGNVSETGRSTLGVHLIRVD
D-TVATMAIVQ-
>tr|U5CJA7|U5CJA7_9PORP DNA gyrase subunit A OS=Coprobacter fastidiosus NSB1 GN=gyrA PE=3 SV=1
AEDFYADDEMIITISHLGYIKRTPLSEFRAQNRGGVGAKGSET-EEDFIEYIYPASMHNYMLFFTQKGKCYWLKVYEIPEGAKNSKGRAIQNMLNIDADD
KVNAFIRVKQ--MSHNLLFCTRKGVIKKTKLEAYSR-RQNGVNAITIREDDQVIQVRLTTGDSQIIMANKHGRAIRFH---VREMGRTATGVRGMTLDTG
-DVIGMICIKDKETVMVVSEQGYGKRSEI-DYRITNRGGKGVKTLNITE-KTGNLVAIKSVT-ENDLVIINKSGITLRMKVADVRIMGRATQGVRLINLE
RNEIASVCKVL-
>tr|R7HQC1|R7HQC1_9BACT DNA gyrase subunit A OS=Prevotella sp. CAG:279 GN=gyrA PE=3 SV=1
AEDFYADDDVIITISHLGYIKRTPLTEFRAQNRGGVGAKGGST-EEDFIEYIYTATMHNYMLFFTQQGRCYWMKVYDIPEGTKTSKGRAIQNLLNIGSDD
KVKAFVNVKG--NSHYLMFCTKNGVVKKTRLEAYSR-RQNGVNAIVIREGDELLQVRMTNGNEEVLLANRNGRAIRFN---VREMGRMSAGVKGMTLDG-
-DVVGMITMPFEKTVMVVSEQGYGKRSVLDDYRVTNRGGKGVKTINVTD-KTGRLVDIKDVD-TKDLVIINKSGITIRLKVADVRVMGRATQGVRLINLE
RNEIASVCVVD-
>tr|A0A0K8R0A3|A0A0K8R0A3_9BACT DNA gyrase subunit A OS=Bacteroidales bacterium 6E GN=gyrA PE=3 SV=1
PEDFYADEDMIITISHLGYIKRTPLSEFKTQGRGGVGSKGGAT-DEDFLEHMFVASMHNTLLLFTKNGKCYWLKVWQIPEGTRTSKGRAIQNVLNISPDD
KVLAYIKVKD--NNNYIILATKQGIIKKTTLEAYSR-RVNGVNAISVREGDELIEARRTSGNHEIMIAVRSGKAIRFN---VRPIGRTSMGVRGITLGE-
-DVIGMICVND-DDVLVLSENGYGKRSSLADYRITNRGGKGVKTINITD-KTGNLISIKNVG-DNDLMIITQNGLTIRVPVKTIRVMGRAAQGVRIINLK
-GSIASVAKVR-
>tr|R5NQ46|R5NQ46_9PORP DNA gyrase subunit A OS=Odoribacter sp. CAG:788 GN=gyrA PE=3 SV=1
PEDFYADDEVVITISHMGYIKRTPLSEYKVQNRGGVGSKGSAT-DEDFLEHLIMATMHNTMLFFTEKGRCFWLKVYEIPEGTKQSKGRAIQNLLNIEPDD
KVKAYINLLK--NSNYIVLCSKKGIIKKTTLEAYSR-RQNGVNAITIKEGDQLLEAKLTNGDNDIMLAVKSGKAIRFP---VRPMGRIAAGVKAIKLKE-
-DVIGMICVEP-ADILVVSENGFGKRSAISDYRITNRGGQGVKTINLTE-KTGNLIALLDVT-EDNLMIITKSGLTIRMEVASLRVMGRNTQGVKLINLR
-DAIAAVAKVS-
>tr|A0A0D8J5A7|A0A0D8J5A7_9BACT DNA gyrase subunit A OS=Draconibacterium sp. JN14CK-3 GN=gyrA PE=3 SV=1
PEDFYADEEMVITISHLGYIKRTPLTEFRTQGRGGIGSKGSTT-DEDFLEHIIIASMHNTLLLFTEKGKCFWLKVYEIPEGTRASKGRAIQNMLNIESDD
QVLAFIKVKA--NNNYIILATKKGIIKKTTLEAYSR-RQNGVNAITIKEGDQLLEARLTNGKSEVMLAVRSGKAIRFN---VRAIGRTASGVRGITLGE-
-DVIGMVCVMD-EDILVVAEKGYGKRSKIEDYRITNRGGKGVKTLNITE-KTGELVAIKSVS-DNDLMIITQKGITIRLAVNTISVLGRATQGVRVINLR
-DRIASVARIA-
>tr|R5YBC5|R5YBC5_9BACE DNA gyrase subunit A OS=Bacteroides sp. CAG:144 GN=gyrA PE=3 SV=1
AEDFYADDEMIITISHLGYIKRTPLTEFRTQNRGGVGAKGSDT-DEDFIEYIYPASMHNYMLFFTQKGKCFWLKVYEIPEGAKNSKGRAIQNLLNIDADD
KVNAFIRVKQ--LTHNLVFCTKKGVIKKTRLEAYSR-RTNGVNAITIREDDQVIQVRLTTGNSEIIMANREGRAIRFH---VREMGRTATGVRGMTLDSV
-DVVGMICVNDTETIMVVSEQGYGKRSEI-DYRITNRGGKGVKTLNITP-KTGKLVAIKNVT-ENDLVIINKSGITLRIKVADIRVMGRATQGVRLINLE
RNEIASVCKVA-
>tr|A5KSZ7|A5KSZ7_9BACT DNA gyrase subunit A OS=candidate division TM7 genomosp. GTL1 GN=gyrA PE=3 SV=1
DEELIPDEDVIVLLTTENYIKRTLVSEYRRQHRGG-G--RMT--MD-VIDQLVPASTHEWLLFFTNRGRVFRIKTYEVPAS-LTAKGVAAVNLL-QQE-E
R--SIIRLE--KDDGYLFMATTHGTVKKTPLKEYSN-R-NGLIAIKLD--DELRW---SN---EVIMSTAFGQAI------ARPMGRSARGVRGIRLRP-
-GLVGMDLAF--HKLLVVSQKGYGKTTKT-NFP-HKRGGVGIKSA---TAKTGNV-AVRSLE-ASEVLIISTKGQAIRVGL-DIPT-GR---GVRIMRLS
E-EVASLGIIP-
>tr|A0A0A7P8W6|A0A0A7P8W6_9BACT DNA gyrase subunit A OS=Candidatus Saccharibacteria oral taxon TM7x GN=gyrA PE=3 SV=1
DEELIPEEESVILLTSENYIKRTLVSDYRRQNRGG-G--RMT--ED-VIDQVVQASTHDYLLFFTNMGRIFRLKAYEVPAS-LSAKGVAAVNLL-QQE-E
K--AIIKHE--NDDGYLFMATQKGTVKKTPVKDYAN-R-NGLIAIKLD--DELRW---TN---DVIISTSAGQAI------TRPMGRSARGVRGVRLRP-
-NVVGMDIVTG-QTLLVVSEKGFGKRTKV-NFP-HKRGGVGIKAA---TAKTGPI-SVQTID-VTEALLVSQNGQTIRLSL-DIKL-GR---GVTIMRFS
D-AVSSIGLMA-
>tr|V5RVU9|V5RVU9_9BACT DNA gyrase subunit A OS=Candidatus Saccharibacteria bacterium RAAC3_TM7_1 GN=gyrA PE=3 SV=1
DEELIPEEDSVILLTGENYIKRTLVSEYRRQHRGG-G--RMT--ED-VIDQLVPASTHDWLLFFTNRGRVFRLKAYEVPAS-LAAKGVAAVNLL-QQE-E
K--SIIRHE--AEDGFLFMATKKGTVKKTPLKDYAN-R-NGLIAIRLD--DELRW---TS---DVIISTSAGQAI------ARPMGRAARGVRGARLRP-
-NVVGMDIVSS-QTLLVISEKGFGKRTTA-NFP-HKRGGVGIKAA---TAKTGPM-SVKTVD-MTDAILISKNGQTIRLGL-DIKM-GR---GVTVMRLG
E-AVCSVGLMP-
>tr|A0A0G4B031|A0A0G4B031_9BACT DNA gyrase subunit A OS=Candidatus Saccharibacteria bacterium GW2011_GWC2_44_17 GN=gyrA PE=3 SV=1
DEELIPEEESVILLTTENYIKRTLVSEYRRQNRGG-G--RMT--ED-IIDQLVPASTHDYLLFFTNRGRIFRLKAYEVPAS-LAAKGVAAVNLL-QQE-E
K--SIIRHE--KDDGFLFMATTKGTIKKTPLKDYAN-R-NGLIAIKLD--DELRW---TN---DVIISTSAGQAV------ARPMGRTARGVRGVRLRP-
-NVVGMDVVDD-RRLLVISEQGYGKATKV-NFP-HKRGGVGIKAA---TAKTGPI-SVQTLE-AGEVLLISNQGQAIRVAL-DIPT-GR---GVRIMKLR
E-AVSSLGLMP-
>tr|R4PVW2|R4PVW2_9BACT DNA gyrase subunit A OS=Candidatus Saccharimonas aalborgensis GN=gyrA PE=3 SV=1
DEELIPEEEAVVLLTTENYIKRTLLTEYRRQHRGG-G--RMT--ED-VIAQLVSASTHDWLLFFTNKGRVFRLKAYEVPAS-LAAKGVAAVNLL-QQE-E
K--SIINHA--PDDGYLFMATTKGTVKKTPLKDYAN-R-NGLITIKLD--DELRW---TN---DVVISTSAGQAV------CRPMGRAARGVRGVRLRP-
-NVVGMDVVTV-QTLLVISQNGYGKITKV-NFP-HKRGGVGIKAA---TNKTGPI-TVQTLE-ANEALLISQGGQTIRVLL-DIPT-GR---GVRIMRLS
E-AVSSIGIMQ-
>tr|R6I9L7|R6I9L7_9FIRM DNA gyrase subunit A OS=Phascolarctobacterium sp. CAG:207 GN=gyrA PE=3 SV=1
MEDLIAEEDIVITISHQGYIKRQTLDNFRNQKRGGVGKTGSGK-NDDCAEHLFLSTTHHNILFFTNKGRVYRQKGYEIPEG-RTAKGTAIINLLPIEQ-E
KITAVIPVK---TEQYMFMATDKGTVKKTNLEDFNS-RKVGLIAITLDENEQLIGVE-TDG-SEIILATRNGIAIRFDE--VRPMGRTAHGVRGIQLN--
-GVVAMDSVTS-SEVLTATEQGLGKRTSVSEYRKQTRGGKGVINIKVN-E-TGIVIGMKVITG-QEIMMITAAGIIIRIDVEGISQFGRNAQGVKLMTLN
DD-VVSLAAVQ-
>tr|R6HNN1|R6HNN1_9FIRM DNA gyrase subunit A OS=Phascolarctobacterium sp. CAG:266 GN=gyrA PE=3 SV=1
IEDLIAEEDIVITISHQGYIKRQTLDNFRSQKRGGVGKTGSGK-NDDCAEHLFLSTTHHNILFFTNKGRVYRQKGYEIPEG-RTAKGTAIINLLPIEQ-E
KITAVIPVK---EDQFMFMATNKGTVKKTNLNDFNS-RKAGLIAMTLDDNEELIGVE-TDG-SEIVLATHRGLAIRFDE--VRPMGRTAHGVRGIQLG--
-DVVAMDSVTN-EEVLTATEEGLGKRTAVSEYRKQTRGGKGVINIKVT-E-TGAVVGMKVINE-QEILLITAAGIIIRIDGEGISQFGRNAQGVKLMTLN
GD-VVSLAAVQ-
>tr|R6X803|R6X803_9FIRM DNA gyrase subunit A OS=Phascolarctobacterium succinatutens CAG:287 GN=gyrA PE=3 SV=1
IEDLIAEEDIVVTISHQGYIKRQTLDNFRSQKRGGVGKTGSGK-IDDSAEHLFLSTTHHNILFFTNRGRVYRQKGYEIPES-RTAKGTAIINLLALMP-E
KITAVIPVK---EEQYMFMATNKGTVKKINLKDLES-RKNGMIAINLDDDEDLIGVE-TDG-SEIILATRNGIAIRFDE--VRTMGRTAHGVKGISLN--
-GVVAMDSVSD-SEVLTATEFGMGKRTEVKEYRKQTRGGKGIINMKIT-E-TGLVIGMKVINA-QEIMMITAAGLIIRTDVDQISQYGRNTQGVKLMTLN
DD-VVSLAAIH-
>tr|D2RMU1|D2RMU1_ACIFV DNA gyrase subunit A OS=Acidaminococcus fermentans (strain ATCC 25085 / DSM 20731 / VR4) GN=gyrA PE=3 SV=1
TEDLIAEEDVVITISHQSYIKRQALTNFRNQNRGGRGIKAGSGIKGDFSEHLLMASTHDNILFFTNRGRVYRQKGFEIPES-RTAKGTFIRNLLPLEENE
KVNAVIAVK---EKKFLFMATNLGYVKRTSVSEFKS-RKGGLIAINLGEGEELIDVK-TSG-NDILLATRDGYAIHFLE--VRPMGRTSHGVRGISLR--
-HVVSMDSCV--GEVLTVTDKGQGKRTDISEYRVQTRGGKGIINLKVT-D-TGLIVGSKFINT-HDIMLISAAGIIIRMNAADISTYGRNAQGVKLMDLE
AGKVAALAIVN-
>tr|U2W468|U2W468_ACISB DNA gyrase subunit A OS=Acidaminococcus sp. (strain BV3L6) GN=gyrA PE=3 SV=1
AEDLIAEEDIVITISHQSYIKRQALTNFRNQNRGGRGVKAGSGITGDFSEHLLLASTHDNILFFTNQGRVYRQKGYEIPEG-RQAKGTFIRNLLPLVENE
KITAIIAVK---ENKFLFMATNKGVIKKTSVSEFKT-RRAGLIAINLDDDEDLIDVK-TSG-HDILLATRDGYAIRFNE--VRPMGRTAHGVRGITLR--
-HLVSMDSCE--GEVLTVTEGGLGKRTDISEYRLQTRGGKGIINLKVT-N-TGDIVGSKLVNH-HDILLISAAGIIIRMKASDISSYSRNAQGVKMMDLE
KGKVAALAIVD-
>tr|G7CIP9|G7CIP9_MYCTH DNA gyrase subunit A OS=Mycobacterium thermoresistibile ATCC 19527 GN=gyrA PE=3 SV=1
DEDLIAREDVVVTITETGYAKRTKTDLYRTQKRGGKGVQGA-GKQDDIVNHFFVCSTHDWILFFTTQGRVYRAKAYDLPEMSRTARGQHVANLLAFQPNE
RIAQVIQIR---AP-YLVLATRNGLVKKSRLSDFDS-RSGGIVAINLRE-DEVVGAV--SAEDDLLLVSANGQSIRFSE--LRPMGRATSGVQGMRFN-D
-DLLSLNVVRPDTYLLVATSGGYAKRTPIEEYPVQNRGGKGVLTIQYD-RRRGNLVGALVVDE-TELYAITSSGGVIRTTARQIRK-GRQTKGVRLMNLA
-GTLVAIARNA-
>tr|U2EFP0|U2EFP0_9BACT DNA topoisomerase (ATP-hydrolyzing) OS=Haloplasma contractile SSD-17B GN=parC PE=3 SV=1
KIDMIKQEDVILTITREGYIKTTKYRTELYKL------------ND-YIVTN-LVTTIDTALIFTNKGNYIYLPLHQIAQ-----LGQHINELVRI-EDE
K--RTIIVK--FEDRFLLLATKNGYIKRTAITDFN----KTFTAIKLK-DDALID---D--DREVIVVTKEGYMV------I--SSTKARGVKSLNLK--
-DVVAAKYIYNDYSLCLFTHRGHIKKVQLK------RGVRGNYTL----NLNHLV-GAILIH--PYILET-TDQHQVLNNV-DISH---NTNGSKFLENK
Q--KRVLEITT-
>tr|A0A0G0KCV5|A0A0G0KCV5_9BACT DNA topoisomerase (ATP-hydrolyzing) OS=Parcubacteria bacterium GW2011_GWC1_38_6 GN=US98_C0003G0005 PE=4 SV=1
ETDIIPQEETIITLTQGGYIKRIDPKTYKMQKRGG-G--LMK--DD-TVAHFLSAKTHDSLMFFTDSGKVFRTLAYEIPES-RVARGRGLLNFL-ESQ-D
K--TLIPVA--SGDKNLVMVTRDGVIKKTILSEFEN-R-SGLIAITLK--DALQK---S---DEIILVTKKGQSI------IRNMGRPAAGIKGMRLK--
GDIVEMEVISTKNYLLIVAENGFGKRTDL-EYR-QGRGGSGIKAI---TPKTGDV-AAKILS-EDELIVISQKGQVIKTKI-SISK-SR---GVRIMKLD
G-KVVSVTCL--
>tr|A0A0G1F537|A0A0G1F537_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWB1_43_6 GN=gyrA PE=3 SV=1
EEDLIPQEETIITLTQGGYVKRINPSQYKNQKRGG-G--MMK--DD-VVEHFLTAMTHDSLLFFTDSGKVFRTQAYEIPEQ-RVAKGRGLLNFL-ESE-E
K--SLNSLG--AGVKYLAMVTKNGIIKKTAIEDFDN-R-SGLIAISLK--DSLKS---TN---ELVIVTKLGQSI------VRSMGRTASGIRGIRLGK-
-GVIAMDVVSTQNLLLVVSENGYGKRTDL-EYK-QGRGGSGIKTA---TSKTGAV-YSMILK--EDLIVISKKGQVIRTPV-AIAK-SR---GVRVMRLD
G-KVASAACL--
>tr|A0A0G1XLQ9|A0A0G1XLQ9_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWA1_48_11b GN=gyrA PE=3 SV=1
EEDLIPEEETIITLTQGGYIKRINPASYRSQKRGG-G--MMK--DD-IVEHILSAQTHDLLMSFTDSGKVFQVPVYEIPET-RVAKGRGLLNFL-ETQ-D
N--SLFAAG--QGMKYLFMVTKNGIAKKTAIDEFKN-R-SGLIAISLK--DALRA---TD---EILVVTKKGQSI------VRSMGRGAAGIHAMRLKK-
-GVVGVDVVPHESYLLVVMENGYGKRTGV-EYR-QTRGGSGVKTA---TQKTGEV-YAKVLC--EDLMVISRKGQVIRTPI-SIAK-SR---GVRIMRMD
--KVVSAACV--
>tr|A0A0G1YQD3|A0A0G1YQD3_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWA1_49_26 GN=gyrA PE=3 SV=1
EEDLVPQEDTIITITQGGYIKRINPSVYKIQKRGG-G--MMK--DD-IVEHFLFAKTHDSLLVFTDSGKVFQAPAYEIPET-RVSKGRGLLNFF-ETQ-D
R--SVFALG--AKVKYLLLITKNGIIKKTPLEDFKS-R-SGLIAITLK--DGLQA---TD---EIIIVTKRGQSI------VRPMGRTASGTHGIRLKK-
-GVVGMDAIAKDAHVLVVMENGYGKRTAL-EYR-QSRGGSGIKTA---TSKTGEV-SSCVLS--EDLIVISRKGHVIRTAI-SIPK-SR---GVRIMKLE
--KVASAACA--
>tr|A0A0G0M005|A0A0G0M005_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWC2_39_11 GN=gyrA PE=3 SV=1
EEDLVPLEETIITLTQGGYIKRINPETYKIQKRGG-G--MMK--DD-VVEHFLDCQTHDSLFFFTDSGKVFRTFVYEIPET-RVARGRGLLNFL-ETQ-D
K--SLITLD--TGVKDLVMVTQNGIIKRTALEEFKN-R-SGLIAINLR--DFLKK---SN---DIIIATKNGQSI------IREMGRATSGIRAISLKK-
-GVVGMDIIRIDLYLLVVTENGYGKRTDL-EYR-QGRGGSGIKTA---TSKTGAV-FSKIVG-DEDLIVISKHGQVIRTKV-LIPK-SR---GVRIMRLE
G-KVASAACI--
>tr|A0A0G1TXE8|A0A0G1TXE8_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWA2_47_9 GN=gyrA PE=3 SV=1
EEDLIPQEETLITLTHGGYIKRLNPGTYKMQKRGG-G--VMK--DD-LIEHFLSAMTHDSLLFFTDSGKVFRCQAYEIPES-RVAKGRGLLNFL-ESQ-E
K--SIMPLG---SAKYILLVTKNGVIKKTELKDFDN-R-SGLIAITLK--DLVSH---TD---EIILVTKKGQSI------VRPMGRTAAGVTGVRLKK-
-GVVGMDIITK--YLLVVTNNGYGKRTEI-EYR-QGRGGSGIKAA---TQKTGDV-ASRVLG--EDLIVISRKGQVIRTKI-SIAK-GR---GVRIMRLD
--KVASAVCI--
>tr|A0A0F9UW82|A0A0F9UW82_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_0214250 PE=3 SV=1
LEDLIPQEETIITLTQGGYIKRINPSTYKIQKRGG-G--VMK--DD-IVEHFLVAKTHDFLLFFTDSGKVFRTPAYEIPEQ-RLARGRGLLNFL-ESQ-E
K--SLISLG--MGIKYLAMVTKEGIIKKTKVQEFEN-R-SGILAITLK--DILKK---ID---TLVLITKKGQAI------IREMGRQAAGVKGIRLKG-
-GVIGMEVIKAREYLLVVTENGFGKKSDL-EYR-QNRGGSGIKTA---TQKTGDI-VSRILT--EDLIVISQKGQVIRTKI-SISK-SR---GVRIMRLD
G-KVASATCI--
>tr|R6BNA0|R6BNA0_9FIRM DNA gyrase subunit A OS=Firmicutes bacterium CAG:56 GN=gyrA PE=3 SV=1
TEDLIPRENVVIAMTKLGYIKRMSVDNFKAQNRGGKGIKGMQT-EDDYIEELLMMNTHHYLMFFTNTGKVYRLKGYEIPEASRTARGTAIVNLLQLAP-E
KITAMIPVK---QGKYLFMATRKGIVKKTPLLDYAN-RKTGLAAISLREDDELIEVK-TNN-KDIFLVTKYGQCIRFPE--VRSMGRTAMGVIGMQLN--
-GVIGMQLNTQGDHLLIVSANGMGKLTSIDEFKSQNRGGKGVKCYKIM-E-TGNVIGVKNLHD-DEIMMINTEGIVIRMMCSDISVLGRVTSGVKLMNLS
-NSVASIAKVR-
>tr|R6PLZ4|R6PLZ4_9FIRM DNA gyrase subunit A OS=Eubacterium sp. CAG:274 GN=gyrA PE=3 SV=1
YEDLIADDMSVITMTQMNYVKRIGLDTYRIQNRGGKGIKGMQT-EEDVVTKLFLSSNHSYLLYFTDMGRVYRTKTYNIPEG-RTAKGTPVVNIIEKSPEE
KISEIIPVK-F--NEYLVMVTKNGVIKKTPASEYESIRKSGKIAITLKEGDELISIFKTTGNDNIFLATRNGMAICFN---ARAVGRTASGVKAIDLA--
-YVVGAEPVREDSKVLLVTDGGYGKCTDLTSFR-QHRGGKGLKAYKITE-KTGNIIGISMVN-SEELIMVTSEGVVIRIRIKDIATTGRITQGVRLINLN
-GIVVSMDKIS-
>tr|A0A0G0U908|A0A0G0U908_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWB1_40_14 GN=gyrA PE=3 SV=1
EEDLIAPEDVIVVLTADGFIKRVSPTQFRSQKRGG-G--AME--ED-AVTNFVFANNHDSLLCFSTKGRVFKVMAWDVPET-RNSRGKAVVNFL-SSQ-E
T--SMVPIA---PPQFLFLATRQGVIKRIAVSEFVN-R-SGITAVALQ--DEVIG---TD---EILLVTKKGKAV------ARPLGRSALGVRGISLSG-
-DVVDLDVIQGKEDVLIVTELAFGKRTDL-QYR-QHRGGAGIKAM---TNKTGPI-GCEILL--EELIVVSVKGQVIRTAL-TIPK-KL---FIRVFRFL
H-KINKSTNRC-
>tr|A0A081BHI5|A0A081BHI5_9LACO DNA gyrase subunit A OS=Lactobacillus oryzae GN=gyrA PE=3 SV=1
DEDLIAEEDVIVSVTHNGYIKRLPTSEFKAQNRGGRGVQGMGV-NDDFIEHLVSASTHDVILFFTNAGKVYRMKGYEIPEYGRSAKGIPVINLLGI-NGE
RVQAVINIS--ESERFLFFTTVQGTVKRTPVDEFTN-RSNGLKAITLHEDDELMNVA-IED-DNMIIGTHQGYAVSFRS--VRSMGRSAAGVRGIRLR--
-DVIGADILEPNSKVFVISEKGFGKQTAASEYPIKGRGGKGIKTANIT-A-NGPLAGLATVSD-EDIMLVTDKGVMIRFGIEKVSETRRATLGVHLIRID
D-KVATMTAVE-
>tr|A0A0R1ZYH6|A0A0R1ZYH6_9LACO DNA gyrase, A subunit OS=Lactobacillus malefermentans DSM 5705 = KCTC 3548 GN=FD44_GL000981 PE=4 SV=1
DEDLIAEEDVIITLTHTGYIKRLPTSEFKAQNRGGRGVQGMGV-NDDFIEHLVSASTHDVLLFFTNAGKVYRMKGYEIPEYGRSAKGIPVINLLGI-NGE
QVQAVINIS--DEQRYLFFTTVHGTVKRTPVDEFTN-RSNGLKAITLKENDELMNIA-ITD-DNMIIGTHLGYAVSFKS--VRSMGRSAAGVRGIRLR--
-DVIGADILQPDSKVFVISEKGFGKQTPANAYPIKGRGGKGIKTVNVS-E-NGPLTGLATVSD-EDIMLVTNKGVMIRFGVEKVSETGRATLGVHLIRID
D-KVATMAVVE-
>tr|B9Y764|B9Y764_9FIRM DNA topoisomerase 4 subunit A OS=Holdemania filiformis DSM 12042 GN=parC PE=3 SV=1
KTAMIPNERVMITASRDGYVKRVSLRSYGASD--N---------GD-VLVGQ-LEDTLDTLLLFTSKGNYAHLPVYQIDE-----VGSHLNKYVSI-DDD
K--NAIVVK--SY-AWIVTVSRRGQVKKTPISQWQ----KMMTAMNLK-D-EMMR---Y---EDLIMISRSGWIS------V--NGTKSQGVKALNLA--
-DLAAACSYSDRQSLWVLSDKGNMKRIKMS------RPVKGEIVV----KLPYHA-YCQCVQ--S--LML-MDPQLQILQA-DVPM---EATFSTPLELK
D--LIK------
>tr|B7C854|B7C854_9FIRM DNA topoisomerase 4 subunit A OS=Holdemanella biformis DSM 3989 GN=parC PE=3 SV=1
EKAMISKEECMITVTRDGYIKRVSMRSFNASS--D---------TD-SLVCY-GAHTLQTLIFFTNRGTYGYIPVYQIEE-----LGGHISNYIKM-DSE
K--AAYVLD--TG-VHVVSASRHGMIKRTELKEFE----KTMTCMKIG-D-EMIS---Y--DDQVILVSEQGYGL------I--VSNKSKGVKAMNLA--
-DVASICIRKNDEQVLISTTTLSLKRMKQL------RPAKGNRIC----KVPNVF-NLQMVD--K--IEI-YTDEILTFEA-EISL---QSTFSMPYGKV
S--WIC------
>tr|R9LPF9|R9LPF9_9FIRM DNA topoisomerase 4 subunit A OS=Firmicutes bacterium M10-2 GN=parC PE=3 SV=1
ETAMIASEQVMVCISEAGYIKRVSMRSYNASS--E---------GD-FMIAS-GENTKDKVLFFTNRGKYGYIPVHLIEE-----LGVHISNYIRL-DNE
R--AAYGVH--PT-IQIVMLSKMGMIKRTPLSQFE----KTMVCMKLG-D-ELIE---A--KDDVYLASFDGLGL------V--SGLKTKGVKAMNLA--
-DMASMLVNED-QQIVVVLQEGMMKRMHAY------RPAKGNRMY----KVPKKD-RLLNA---N--YTF-VSEDKVELKP-DLSL---TATYSTPFGKI
H--WVN------
>tr|U2R737|U2R737_9FIRM DNA topoisomerase 4 subunit A OS=Faecalitalea cylindroides ATCC 27803 GN=parC PE=3 SV=1
EKAMIANEQVIVPITRDGYVKRVSMRSYNASN--D---------SD-KLVTY-GSSTLDTLLFFTNRGTYGYLSVYQLEE-----LGSHLSSYIKM-DGE
K--QAYLLS--ES-VEVLCVSRFGMIKRTNLKELQ----KTMVCMKIG-D-EMVS---Y--DDVVILSSEQGFAL------V--VSCRSKGVKAINLV--
-DVADMIVVSNDGQLVVISDTAQMKRIKAS------RPAKGNRIC----KVPVKD-RLLSKQ--V--IEF-QHDELVRFAA-EVSL---DSTFSSPFGKV
E--IPS------
>tr|D2MM14|D2MM14_9FIRM DNA topoisomerase 4 subunit A OS=Bulleidia extructa W1219 GN=parC PE=3 SV=1
KEAMIPSEQVMITVSKDGYLKRVSLRSFNAVR--D---------GD-QLIGQ-RENTLDTLLLFTSKGNYAMVPVWQIDD-----IGSHLNKLVRV-DEE
K--SAIVVK--SY-AWITLVTKGNKIKKTKLSDWK----RLFKAINLE-D-EVCA---Y---QEVLVVTKDGYAL------I--VK-ASKGVQAMKVA--
-DVAFATSVYSD-NLLFLTDTLQAKRIHLE-----RAKNMGERIC----KNPSRQ-YVLAVK--N--LEF-GGEFRQILST-DIPF---EMGFSTLSLDK
H--LKL------
>tr|H1BKM2|H1BKM2_9FIRM DNA topoisomerase 4 subunit A OS=Eubacterium sp. 3_1_31 GN=parC PE=3 SV=1
KVAMIPQEQVMFTISRDGYVKRVSMRSYGAAN--D---------GD-HLIGY-GENTLDNILFFTSKGTYGYVPVYEVDD-----IGSHINSKIKI-TDE
K--DAFIVK--TN-AYMLSITRHGLVKKTAICEYE----KTMSNMKLL-D-EVVQ---Y---DEILIASKKGYIT------I--TSPRSKGVKAMNLV--
-EIASALIYNNNRQLVVFSDNCACKRMKLT------RPTKGSMLC----KVPYHA-YISLHD--E--IVI-ANSEIHKVVS-DIPL---DATFSAMLKGI
D--LLK------
>tr|T4NE80|T4NE80_PEPDI DNA topoisomerase 4 subunit A OS=Peptoclostridium difficile P28 GN=parC PE=3 SV=1
KLAMINSEQVMFTISRDGYFKRVSMRSYGASR--D---------GD-HLVGY-GENTLDHVLFFTTQGTYGYTPVYDVEE-----IGSHINSTIRI-SEE
K--DAFVLR--TN-AYMISVTKNGLVKKTAVREYE----KTMSNMKLL-D-AVVK---Y---DEILIASKNGFVS------I--TSPRSKGVKAMNLV--
-EIVSACISHGASQLIVFTDQCQMKRIKLS------RPTKGSMIC----KVPYQA-HIALHD--E--LVI-INEETQKILA-DISL---DATFSSPLHTT
D--FLR------
>tr|A8RB69|A8RB69_9FIRM DNA topoisomerase 4 subunit A OS=[Eubacterium] dolichum DSM 3991 GN=parC PE=3 SV=1
KLAMINEEQVMFTLSRDGYAKRVSLRSYNASS--D---------GD-RLIGC-GESTLDKILFFTNMGTYGYVPVYELEE-----VGTHLNAGIRM-REE
K--DAFVVK--SQ-AYVVSVTRMGLIKKSALSEYE----KTMSNMKLL-D-EVIR---Y---DEIFIASETGFAV------V--TSPRSKGVKAMKLV--
-VIGDACIYHQNKQLVVFSKNGAVKRMKLS------RPAKGNMLC----KVPYKA-HLQMYD--E--VYI-MGKDICSVVS-DIAL---EATFSAPLVRD
E--LFT------
>tr|E7MP94|E7MP94_9FIRM DNA topoisomerase 4 subunit A OS=Solobacterium moorei F0204 GN=parC PE=3 SV=1
KTAMIANERVVVTVSRDGYLKRVSMRSYNAVG--D---------GD-VLIGT-TEDTLDTLLLFTSKGNYASIPVWQIDE-----VGMHLNKVVRI-DED
K--NAILIK--TY-AWIVTVSSAGQIKKTPVNNWQ----KVMTAMNLS-A-EMIH---Y---QQILMVSKDGYSY------I--TGVKSKGVKAMNLG--
-DLAWGCVMNADPAVLYMTNVGQMKRIHTE------RPMKGNLIC----KLPSIT-LAKAVS--E--LIF-KDPERQVLRA-EVPL---ESGFGSPLVLK
G--LYR------
>tr|R6BM53|R6BM53_9CLOT DNA topoisomerase 4 subunit A OS=Clostridium sp. CAG:524 GN=parC PE=3 SV=1
TLDMISKEDFIVCISNSGYVKKVSMKSYNAT--PN---------ND-YITGF-FKNNVDTVLLFTNLGNYLYLPVRDINE-----IGSHISNYIKV-SGE
K--QSFGIS--K--TIITAFTKNGMVKRMTLKDFE----KPIAMFKLK-D-EVIS---M--YEDTIVVTKEGYAL------I--VGLRTSGVKSINLG--
-DVISSFNVDPKEYITVFTDRNTAKRIKVD------RAKKGSLII----KPQYNF-RCYNTN--I--FGIL-DGDIGYMKS-DINI---LSTGSQITKKN
E--F--------
>tr|R7HG24|R7HG24_9MOLU DNA topoisomerase 4 subunit A OS=Mycoplasma sp. CAG:472 GN=parC PE=3 SV=1
LKDMIPKEDVIVVVTNDGYIKKVPMKSFKAAT------------GD-FVRNM-FENTRDYILSFTSLGNYLFIPVHTITE-----LGKHISNLIMI-KNE
R--NSFIFE--S----LVLTSKEGMIKKVRMEEFE----KPMTSIKLK-D-ELIS---E--GKKTLILTDNNYYL------I--VGPKASGVKGYPIK--
-NIS-SSQINDDEYINIFTNLNTAKRVKLS------RNKKGKEII----KNDYRI-SAFTSN--I--NVIKTNDDVNEIKN-DIPI---NSFGSTYTKLK
V--KPK----Y-
>tr|R5A1Y6|R5A1Y6_9CLOT DNA topoisomerase 4 subunit A OS=Clostridium sp. CAG:1000 GN=parC PE=3 SV=1
ELDMISKDDFIVCISKTGYVKKISLKSYNSSN-TQ---------ND-YIEGF-YKNNIDTIILFTNLGNFLYLPVRDIQE-----LGTHISNYIKV-SDE
K--RSIGVD--D--TLITAVTKNGMIKKMRLKEFA----KPITMFKLK-D-EVVS---S--GKDTVIVTNSGYAL------I--FGLKAGGVKAIKLS--
-DVSSAFVISEKEYLAIFTDKNTAKRIKVE------RAKKGSLII----KPKYSF-KAFNIS--I--VGIV-DGSIGYLKS-DINI---QSVGSVITKKN
D--F--------
>tr|R5VDT0|R5VDT0_9FIRM DNA topoisomerase 4 subunit A OS=Coprobacillus sp. CAG:605 GN=parC PE=3 SV=1
TTDLITKENVLVCITNEGYIKRVSLKSYNSSN--G---------GD-YVTNL-FESTLDTILIFTNLGQYIYAPVHSIFE-----LGKHINNLVGG-SEE
H--ASFVLD--D--QEITTFTKNGLVKRSVFKDYV----KAMSAFKLK-D-YVVS---T--TSRTLMVSANGYYV------I--VGPRASGVKGIALK--
-Y-VGGYSIDSHEYLTLITNNKTAKRIKIS------RAKKGSSLI----KVDYQT-KCLLTT--E--VCIKADSEIKTLKN-EIPI---KSTGSNISKYN
D--FLP----F-
>tr|R5IUW1|R5IUW1_9FIRM DNA topoisomerase 4 subunit A OS=Firmicutes bacterium CAG:822 GN=parC PE=3 SV=1
TTSLIPKEDCIVVVTNEGYVKRVSLRSYAASN--N---------KD-YKTAI-YENTMDTLLLFTSLGNFLYVPVYELPD-----MGKHISNIIKI-SDE
D--SSYLTK--EN-VNFLSFTKNGMVKQTSVADLK----KPVTLMKLK-D-KVIS---A--ENEVFVTTHNGFAL------V--TGLRGSGVKAINLK--
-YISGQSFT--AEYALFVTDKGTGKRVKLN------RARKGLMAI----RVPYKI-SAFIIN--A--IGI-LTDEITYHKS-EFPI---YQTGANITKDK
N--FIE----S-
>tr|C0WMC6|C0WMC6_LACBU DNA gyrase subunit A OS=Lactobacillus buchneri ATCC 11577 GN=gyrA PE=3 SV=1
DEDLIEEEDVIVSLTHNGYIKRLPTTEFKAQNRGGRGVQGMGV-DDDFVEQLVSTSTHDVLLFFTDAGKVYRMKGYEIPEYGRSAKGIPIVNLLNI-NGE
KIEAVINVS--DVQKDLLFVTLYGTVKRTPVSDFAN-RSNGLIAIHLKEGDQLINAL-IDQ-QNVIIGTHLGYAMSFNA--VRSMGRSATGVRGIRLR--
-NVVGADVLNPDSEVFIISEKGFGKRTPAADYPIKGRGGKGVKTANIT-E-NGPLSGLTTVSN-EDIMLITDKGVMIRFGIEDVSQTGRSTLGVHLIRID
D-KVSTMAKVE-
>tr|Q1NV33|Q1NV33_9DELT DNA gyrase subunit A OS=delta proteobacterium MLMS-1 GN=gyrA PE=3 SV=1
PEDMIAREEMVVTVTHAGYIKRNPVDTYRSQRRGGKGIKGAGT-DEDFVSWMQVASTHDTLLFFSNKGRVFWRKVYEIPQAGRLARGKAVVNLLELGA-E
KVAAILPVDT-GGARYILMATKKGVVKKTALSEFAR-LKRGKIALTIREDDEILGAS-TTG-NEVLLLSRRGMAVRFHE--IRAMGRGASGVRGITLA-D
DELIGLQVLSGEASILVVSENGFGKRSKVDEYRLIRRGGKGVMAIKAS-E-NGEVVGMSQVCD-DQVMMITNRGQIIRMPMQGIRVIGRSTQGVRLFNLD
-EKVVALDRLA-
>tr|A0LLR6|A0LLR6_SYNFM DNA gyrase subunit A OS=Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) GN=gyrA PE=3 SV=1
IEDLIAAEEMVVTISRAGYIKRTPLSVYRSQRRGGKGRTGMST-EEDLVTSLFTASTHDYLLVFTNRGQVYWLKVYEIPEVGPSALGKAIVNLLPVQK-E
RIQTVLPVKG----FFAVMATRNGVIKKTDLSAYSN-RSTGIRAIVLDDDDELISVC-TDG-HDLFLMSRAGKSIRVNE--FRPLGRVSRGVRGMKLD--
SRMVGMDVIE-GKAILVITEKGFGKRTNAEEYRCQSRGGKGVLNIRVT-E-NGSVVGFRQVGD-EQILMITDHGRLIRMPVAQISRIGRVTQGVKLMNLN
-GKVVDVAVLP-
>tr|K1XZU8|K1XZU8_9BACT DNA gyrase subunit A OS=uncultured bacterium (gcode 4) GN=gyrA PE=3 SV=1
MEDLIADESCIITLSHAGYIKRVPANTYKAQKRGGRGVTGMIT-EEDYVEHVYSAMTHDTMLIFTSTGMLHWLRVFHIPEASRVAKGVSIANLL-NSNEE
KIASMITVR---EDKTIVMATKKGVIKKSNLSLFSNIRKKGIIAINIKEEDALIQAA-SSGKDDILLSTSKGLSIRFNE--VSEMGRSATGVRGVKLK--
-DVISMEIVKSILNLLIVCENGFGKRSPFEEFRITNRGGKGVISI--TR--NGDVVTALAVKDDDDIMVITSSGMMVRINVKGISIQGRNTQGVKIVNLK
-NKIVSITTIE-
>tr|V4J458|V4J458_9DELT DNA gyrase subunit A OS=uncultured Desulfofustis sp. PB-SRB1 GN=gyrA PE=3 SV=1
PEDLITPEDMAVMVTHSGYIKRNSVSLYRAQHRGGKGVRGLTH-EDDFVTNLYVASTLDTFLFFTNFGKVFWRKVYQLPMAGRTARGKAIINLLELGE-E
RVAAILPISE-TASQTILTVTKYGKVKKTALREFAR-LKKGKRALTINEGDEILSAH-LGG-DTVFLISHHGLSIRFHE--VRTMGRIAAGVRGIKLK--
DYVVAANVLASEESILIVTENGYGKRTIATEYRTQFRGGKGIIAIKPS-L-NGPVIGAQIVDL-SDVILIADSGQMIRMGVESVRIIGRTTQGVRMINLS
-SRVVGMAVVD-
>tr|E8RH59|E8RH59_DESPD DNA gyrase subunit A OS=Desulfobulbus propionicus (strain ATCC 33891 / DSM 2032 / 1pr3) GN=gyrA PE=3 SV=1
PEDLITPEEMVVTVSHTGYIKRNPLTLYRAQRRGGKGVKGMVT-EDDFVTSLYTASSLDTFLFFTNKGRVFWRKVYELPLAGRTARGKAIVNLLELGE-E
KVAAILPVAM-DDTVSVLTVTKQGRVKKTFISEYKR-LRKGKFGLTIRDDDEILSAA-TSG-DEIFLVTKKGLSIHFHE--VRAMGRLAAGVKGITLG--
DEVVGVAVLK-DASILTVTENGYGKRTAVSEYKLQSRGGKGVFTIKTS-E-NGNVVGVLPVVE-DQVMLVANSGKVIRMPMDTVRIIGRNTQGVRLINLD
-GLVVDMSMLA-
>tr|A0A0G0W8K9|A0A0G0W8K9_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWB1_41_4 GN=gyrA PE=3 SV=1
EEELIKEEQAIISLSREDYIRRINPESFRLQKRGG-G--AFE--DDDIPQLVRSCSTHDLLLFFTNTGKLFYVKAYEIPEG-KLARGKPVNNFL-NSE-E
K--SFIPYH--TQFQYLDLVTKSGLAKKIKISDILGNR-NGSRIIGLQ--DGVMA---SD---NIVLVSRSGQLI------LRVQGKAAKGVKAMGLKK-
-GIISMGIANKTQKLLVIMKRGFGKMSLI-DFR-QKRGGSGVKSA---NEKTGEV-MAKIID-EQDLVIISADGQTLKLEL-GVPV-GR---GARLIKLD
D-KVAAAVCF--
>tr|M1P7I8|M1P7I8_DESSD DNA gyrase subunit A OS=Desulfocapsa sulfexigens (strain DSM 10523 / SB164P1) GN=gyrA PE=3 SV=1
PEDMITQEDMAVTVTHTGYIKRNPVSIYRSQKRGGKGVLGVKN-EEDFVSNLYVASTHDTFLFFTNHGKIFWRKVYQLPLAGRTARGKAIVNLLNLAE-E
KVAAILPVAE-KITKTILMVTRLGRVKKTSLEEFIK-LKRGKKALTINEDDEIISAH-LTG-DTIFLFSKYGSSIHFHE--VRTMGRTAAGVRGIRLK--
DYVVGSIVID-DSSILTVTENGYGKRSPVADYRIQKRGGLGIMAIKTS-E-NGYVVGAMQVDD-SEVMLIADSGKMIRMPMSNVRVIGRTTQGVGLINLA
-DRVVAMDLVA-
>tr|D6Z5P0|D6Z5P0_DESAT DNA gyrase subunit A OS=Desulfurivibrio alkaliphilus (strain DSM 19089 / UNIQEM U267 / AHT2) GN=gyrA PE=3 SV=1
PEDMIAREDMVVTVTHAGYIKRNPVDLYRAQRRGGKGIRGAGG-DDDFISWMHVASTHDTLLFFTNRGRVFWRKVYEIPQAGRLARGKAVVNLLDLAP-E
KLAAILPVQP-GRECYILMATRKGVVKKTTIQEFSR-VRRGKIALTFREDDEILAAA-TYG-NEILLLSRKGMAVRFHE--IRPMGRGATGVRGINLG--
DELVGVSVLSGETSILVVTENGYGKRTLVDEYRLIRRGGKGVMAIKAS-E-NGAVVGMLQVTE-DQVMMITNAGQIIRMPMTDLRVIGRNTQGVRLFNLG
-EKVVALDRLA-
>tr|Q6AQJ4|Q6AQJ4_DESPS DNA gyrase subunit A OS=Desulfotalea psychrophila (strain LSv54 / DSM 12343) GN=gyrA PE=3 SV=1
PEDLIAPEDMAVTVTHSGFIKRNPAALYRSQHRGGKGVSGAKN-EEDFISDLYVASTLDTFLFFTNYGKVFWRKVYQLPLVGRTARGKAIVNLLELDE-E
KLAAILPVTE-DKSKTILMVTKQGRIKKTSLQEFRR-LRKGKRALTINEGDEIIGAY-LNG-DTVLLCTSKGKAIHFHE--VRTMGRTAAGVRGITLG--
DEVVSAIVAS-NDSILVVTENGYGKRSPIEEYRIQKRGGKGIIGIKQS-E-NGDLISAKQVSE-EEIMIIADSGKMIRMNLENVRIIGRSTQGVRLINLE
-DKVVSMDTVA-
>tr|A0A0F2NDN9|A0A0F2NDN9_9DELT DNA gyrase subunit A OS=Desulfobulbaceae bacterium BRH_c16a GN=gyrA PE=3 SV=1
PEDLIAPEDMAITVTHSGYIKRNPVSLYRSQHRGGKGVTAVKN-EEDFVSSLYVASTLDTFLFFTNHGKVFWRKVYQLPLAGRTARGKAIVNLLNLAE-E
KIAAILPITE-SNNKTILMVTKFGRIKKTSLQEFIR-LRKGKRALTINEGDEIIAAH-LNG-DTVLLVTKQGMCIHFEE--LRTMGRTAAGVRGITLR--
DVVVSAIVIE-DNSILIITENGYGKRSPIDEYRLQKRGGKGVIGIKRS-A-NGNVIAAKQVDE-EEVILIADSGKMIRMDLSSIRVIGRSTQGVTLINLD
-NKVVGMDSVA-
>tr|A0A0J7HPW5|A0A0J7HPW5_9BACT DNA gyrase subunit A OS=haloalkaliphilic bacterium ACht6-1 GN=gyrA PE=3 SV=1
IEDLIAEEDMVVTMTRDGYIKRTAATTYRAQGRGGRGVKGMES-ENDFISSLFVASTHAYILFFTNQGRCHWLKVYRIPEAGRNSRGKPIVNLLNLRP-E
KIAAFVSVR----EHFIITATEQGVINKQPLSSYSN-RKGGINAINLDEGDSLIECK-TNG-NDVILGTRFGQAVRFHE--ARELGRNTRGVKGITLK--
DKVVSMIIA--EHEVLSVTDNGYGKRTPVTEYRKTNRGGSGIINIKVT-E-NGSVVSLKNVYD-NDLMIITRNGIIIRVDVNKISTIGRNTQGIRLINLD
-DRVIDIALCE-
>tr|H1Z878|H1Z878_MYROD DNA gyrase subunit A OS=Myroides odoratus DSM 2801 GN=gyrA PE=3 SV=1
ITDLIADEQVVITISHAGYIKRTPLSEYKTQNRGGVGQKSAGT-DQDFLEHMYVATNHQYMLFFTQKGKCFWMRVYEIPEGTKVSKGRAIQNLINIENDD
KVKAFICTQK--NNHYVIMATKQGQVKKTPLEQYSR-RQNGINAITIKEDDELLEAKLTDGKSKVLIAVKSGKLVRFD---TRPMGRTASGVRGITLAD-
-DVIGMVSVSDNSEILVVSENGYGKRSAL-EYRETNRGGKGVKTMNISE-KTGLLVSINVVT-ADDLMIINKSGLTIRMRISDLRVMGRATQGVRLINIK
-NSIAAVCKVM-
>tr|V6S0Y2|V6S0Y2_9FLAO DNA gyrase subunit A OS=Flavobacterium enshiense DK69 GN=gyrA PE=3 SV=1
IEDLIADEQVVITISHAGYIKRTPLSEYKTQNRGGVGQKSAGT-DQDFLEHMYAATNHQYMLFFTQKGKCFWMRVYEIPEGSKTSKGRAIQNLINIENDD
KVKAFICTQK--NNHYVIMVTKQGQVKKTSLEQYSR-RVNGVAAITIKEDDELLEAKLTTGNSQVLIAVKSGKLVRFE---TRPMGRTASGVRGITLAEK
-DVIGMVSIDRDSQILVVTENGYGKRTKVVVYRITNRGGKGVKTLNITE-KTGALISINNVT-EDDLMIINKSGLTIRMKVSDLRVMGRATQGVRLINIK
-KAIAAVCKVM-
>tr|A0A0P9CU24|A0A0P9CU24_9GAMM DNA gyrase subunit A OS=Thiohalorhabdus denitrificans GN=AN478_08515 PE=4 SV=1
LEDLVAEEDMVVTMTRAGYIKRQPLSGYRAQRRGGKGAAAA-TRAEDFVERLFVASTHQYILCFSNAGKVYWLKVYELPEAGRTARGKAIVNLLPLE-DE
RITTVLPVDAFEEGRYVVMATSKGVVKRVDLMDFSRPRKAGIIAIKLDQGESLVGARITGGNDEMLMATNRGKAIRFPEQEVRIMGRNAHGVRGIEMAE-
-DLIGLQVVRPGWEVLTVTENGFGKRTPLDEYRLQGRGGQGILTIKVSE-RNGEVVSVRLVHPDNEVMLVTSQGTLIRTPLEGISRMGRNTQGVRLIDLA
KGRVVGAERVE-
>tr|A0A0J6YU37|A0A0J6YU37_9BACT DNA gyrase subunit A OS=Nitrospina sp. SCGC_AAA799_A02 GN=gyrA PE=3 SV=1
IEDMIADEDVVVSYSRSGYIKRQSLDNYRSQRRGGKGIKGMKV-EEDVVENLFIASTLDYLMVFTSIGKVHWLKVYEIPDVRRTSKGKSIANLLHLKP-E
SIAGILSVKG----KNVLVTTERGVVKKTSLMAYSK-RQGGIIGLTLDQDDRVIAAE-TDG-QDILLVTAKGFSIRFSE--VRAIGRTGRGVRGIRLK--
DRVVGACVAE-GTAILTVTDKGYGKRTQMEEYPVQGRGGLGVINIKCN-E-IGSVIGVEQVTN-DEILVITSDGNIVRMRVDEISIIGRNTQGVRVVGLK
-DLVVCAEKLM-
>tr|R5NKR2|R5NKR2_9BACT DNA gyrase subunit A OS=Paraprevotella clara CAG:116 GN=gyrA PE=3 SV=1
PEDFYADDEMVITISHMGYIKRTPLAEFRAQARGGVGSKGTST-DTDFVEYIYPATMHNTMLFFTQKGRCFWMKVYEIPEGAKNSKGRAIQNMLNIDPDD
AINVCLRIKN--RSHYVVFCTKNGIIKKTCLQEYSR-RTNGVNAITIREDDRVIGVRLTNGENEIIIANRNGRAIRFH---VRAMGRTATGVRGMTIDDG
-DVVGMVCVNDTETIMVVSEQGYGKRSDI-DYRVTNRGAKGVKTLNITE-KTGKLVAIKVVT-ENDLMIINKSGITIRLKVADVRIMGRATQGVRLINLE
RNQISSVCKVQ-
>tr|H1Z3J6|H1Z3J6_9EURY DNA gyrase subunit A OS=Methanoplanus limicola DSM 2279 GN=gyrA PE=3 SV=1
KEDLIENKPVLISLTGENYIKSMPLDTYKGQKRGGKGIIGMAC-DEDAVKSVFVANSHDYLLCFTSAGRVYWLKVYDIPEASRQSRGKAIVNLLNLGD-E
KVSALIP---FS-DEFFLFSTKHGMVVKIPQDEFSRPRTTGMNAITLRDDDELVGVL-MGDDGELVLTSVQGQTLRMGA--IPLRHRNALGVKGMKLR--
-DLKDISAV-EMDHLLTVTEKGYGKRTDFGEFRGHGRATMGVRNI--D---AGGVVASRAVSDDDEIILMSSSGIVIRTKVSEISIQKRGTRGVRVMKVD
-DSVVGFTVLG-
>tr|A0A0Q1FDI4|A0A0Q1FDI4_9EURY DNA gyrase subunit A OS=Methanoculleus sp. SDB GN=APR53_02505 PE=4 SV=1
REDLIEDKPVLVSLTAHNYIKRMPLETYRGQHRGGRGIIGMAT-EEDYVENVFTANTHDYLLCFTSQGRVYWLKVYDIPEAVRTGKGKAIVNLLNLQDE-
RVTTIIPVR---EDHYFLFATRYGTVAKITQAEFSRPRQTGINAITLREGDELVDVK-TDGTSELILTTRHGQSLRFRE--VRTLHRNAMGVRGIKLR--
-DLQCVTVVEH--HLLTITERGFGKRTEFDEFRGHGRGTMGVRNI--DQ--SGGVVASRAVSNDDDIILMSTSGIVMRTPVSEISIQKRNTRGVRIMKMD
-GRVVDFAVLQ-
>tr|E1RIX3|E1RIX3_METP4 DNA gyrase subunit A OS=Methanolacinia petrolearia (strain DSM 11571 / OCM 486 / SEBR 4847) GN=gyrA PE=3 SV=1
KEDLIENKQVLVSLTSHNYIKSMPLDTYKGQHRGGRGIIGMST-DEDFVKSVFVASTHDYLLCFTSSGRVYWLKVYDIPEATRQSRGKAIVNLLELGDEE
KVTAVIPVS---EDEFFLFATLNGMVVKIPQVEFSRPRQSGIYAITLKDGDELVHVM-AVDSGEIILTTRMGQSLRFGI--ISLRHRNALGVKGIKLR--
-DLQDVTPVEK--HLLTITEKGYGKRTEFDEFRGHGRATMGVRNI--DV--SGGIVSSKAVSDDEDIILMSRSGIVIRTKVSEISIQKRGTRGVRIMKLD
-GSVVGFTILD-
>tr|Q2FUD5|Q2FUD5_METHJ DNA gyrase subunit A OS=Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 / JF-1) GN=gyrA PE=3 SV=1
REDLIPNKQVLVCLTHQNYVKHMDVDAYRVQGRGGRGVMGISI-DGDYVEQVFVANTHDHLLCFTSTGRAYWLRVFDIPEGSRQSKGKAIVNLLDLRSEE
RVTAVIP---FS-DRFFLFLTERGMIIKIPQDEFSRPRSTGVNAISLREGDNLVHVM-SDGSQEIIITTKYGQSLRFHE--IPLRHRNALGVIGMRMK--
-DVTSMTVIEEGKHLLTITSSGYGKRTNFDEYRGHGRGTMGVRNI--K---NDGIVTAFSAGPEEEIILMSAEGIVIRTSVEKITIQGRSTQGVRIMRLA
-GRVVGVTSLS-
>tr|R6DH18|R6DH18_9BACE DNA gyrase subunit A OS=Bacteroides sp. CAG:530 GN=gyrA PE=3 SV=1
PEDFYADDEMVITISHLGYIKRTPLSEFRAQNRGGVGSKGSET-DEDFIEHIYPATMHNTMMFFTQKGKCYWLKVYEIPEGNKTSKGRAIQNLLNIEPGD
VVTAYLRVKN--NSHYVLFCTKNGVIKKTLLEQYSR-RQNGVNAITIREDDRVIEVRMTNGNNEIVIANKNGRAIRFH---VRDMGRTATGVRGITLDDG
-DVVGMICIKDKETIMVISENGYGKRSDI-DYRKTNRGGKGVKTLNITD-KTGKLVAIKSVT-DNDLMIINKSGITIRLRVADVRIMGRATQGVRLIDLE
RNHIGSVCKVT-
>tr|A0A0C3RI66|A0A0C3RI66_9PORP DNA gyrase subunit A OS=Sanguibacteroides justesenii GN=gyrA PE=3 SV=1
PEDFYADEEMVITISHMGYIKRTPLSEYKVQNRGGVGSKGSAT-DEDFLEHMITATMHNTMLFFTEKGKCFWLKVWEIPEGTKQSKGRAIQNLLNIEPDD
KVKAYINILK--NSNYIVLCSKQGIVKKTTLEAYSR-RANGVNAITIKEGDQLLDAKLTNGENDIMIAVKSGKAIRFP---VRPMGRTASGVRGITLGE-
-DVIGMICVEP-ADILVVSENGYGKRSDIEDYRITNRGGKGVKTINLTE-KTGNLISLIDVT-DDNLMIINRSGLTIRLDISTLRVMGRNTQGVKLINLR
-DAIAAVAKVS-
>tr|I4CB96|I4CB96_DESTA DNA gyrase subunit A OS=Desulfomonile tiedjei (strain ATCC 49306 / DSM 6799 / DCB-1) GN=gyrA PE=3 SV=1
DEDLIPRGDMVVTFSSRGYVKRVPANLYKSQRPGGKGRIGTKV-EDDVVNQILYASSHDVLLCFSNRGRVHWLRVFQLPEESPYARGKAIINLL-RDPGE
KIRKILPVQ---TEGFVVMTSRQGKIKKTAIEEFSRPRLSGLIALTIDPDDELIDVN-TTGENHILLATARGLAMRFHE--VRPMGRQARGVTGIRLK--
-DVIGMEVVSD-GTLLTITRSGFGKRTSLEEYPSKNRGGQGVITI--TK--LGEVVAVKVVGDTDHLLILTSGGKIIRLRMEEISVIGRNTMGRTLVRMD
-GYVVDVARAE-
>tr|A0A098EFU7|A0A098EFU7_9BACL DNA gyrase subunit A OS=Planomicrobium sp. ES2 GN=gyrA PE=3 SV=1
DEDLIPREDSVLTLTHNGYIKRLPANTYRSQKRGGRGVQGMGT-EDDFVEHLLYTSTHDTILFFTNKGKVYRKKGYHIPEYGRTAKGLPLVNLLEIEK-E
KVTAVIRVE---EDAFFFFTTREGVSKRTPVSNYAN-RQNGLIAISLREEDELISVK-TDG-KEIVIGTRDGALIRFPE--IRSMGRTASGVRGIRLR--
GDVVGMEILEPGDNILVITEKGYGKQTKEAEYRVQSRGGMGIKTCQIT-DKNGPLVAVRTVNT-EDIMLITINGILIRMDVNDISTTGRSTQGVRLIRLS
-DTVATVAKVK-
>tr|F9DV54|F9DV54_9BACL DNA gyrase subunit A OS=Sporosarcina newyorkensis 2681 GN=gyrA PE=3 SV=1
DEDLIPVENSIVSLTHQGYIKRLPANTYRSQKRGGRGIQGMGT-EDDFVEHLLNTSTHDTILLFTSRGRVFRKKGYEIPEYSRTAKGLPIINLIDFEK-E
KVTAMIPIS---EDHYLFFATKHGVIKRTSIMGYAN-RANGLIALGLREEDELISVK-TDG-SDIAICTKQGMLIRFAE--IRPLGRTAAGVRGIRLR--
DDVIGMDMVDEGDDILVVTEKGYGKRTPESEYRSQSRGGYGLKTMHMT-DRNGEIVAMKAVNE-EDLMLITIHGILIRMSISDISIFGRSTQGVRLIRLA
-DRVATVAKVE-
>tr|S2XGG8|S2XGG8_9BACL DNA gyrase subunit A OS=Paenisporosarcina sp. HGH0030 GN=gyrA PE=3 SV=1
DEDLIPRENSVLTLTHNGYIKRLPVNTYRSQKRGGRGVQGMGT-ENDFVEHLLYTSTHDTILFFTNTGKVYRAKGYEIPEYGRTAKGLPIVNLLGVDK-E
KVTAMIQMA---DDAYFIFTTRLGVTKRTPVSGFAN-RANGLISISLRDDDELISVR-TDG-KHIIIGTRNGMLVRFEE--IRSMGRTASGVRGIRLR--
DDVVGMEILEPGQEVLVVTENGYGKRTPEEEYRLQSRGGVGIKTSQIT-DKTGPLSAVKAVDS-EDLMLITINGMLIRMDVNSISITGRSTQGVRLIRLG
-DLVATVAKVE-
>tr|B9Y585|B9Y585_9FIRM DNA gyrase subunit A OS=Holdemania filiformis DSM 12042 GN=gyrA PE=3 SV=1
DEDLIPQEDVVITMTVNGYVKRIPVDTYRLQNRGGKGIKGMSM-EDDIVDQFLTMMTHDYLLMFTNQGKVYRIKGYQVPLS-RTSKGIPIVNLLNLDK-E
KVLAMVPVE--SPAKFLFFVTAQGIVKRVPIEEFEN-RQSGKIAINLREGDELISAK-TTG-SQILIAAANGQAIRFNE--VRPMGRTATGVKGFNVN--
-SVIGMTTDFE-QYILSVTEKGYGKKSKLEDYRMTNRGGKGVKTIQVT-D-NGPLVFLRAV-G-EDCLIMTNEGIVIRISLEKVSVYSRNTQGVKLISVE
NQ-VSTVAIVY-
>tr|K0NRS9|K0NRS9_DESTT DNA gyrase subunit A OS=Desulfobacula toluolica (strain DSM 7467 / Tol2) GN=gyrA PE=3 SV=1
IEDLIAQEDMVVTVSRSGYIKRNPITLYSSQHRGGKGKTAMGT-TDDFVEHLFVASTHSTFLFITNLGKVYQAKVYELPMAGRSSLGKAIVNLLNFDE-E
KLATVLTVDD----RYVVMATKKGRVKKTDLMAYSR-RSGGLIGVKLAEGDELIAAR-TDG-MDVFLGSEGGKVIRFNE--VRATARGSMGVRGMRID--
TKVVGMEVLE-EDTLLTVTENGYGKRSSIEEYRTQTRGGKGVFSIKTS-K-NGKMVSLLLVDN-DELMMVTDKGKLIRTSIEGINVISRNTQGVKLINLS
-KTLIGIARLP-
>tr|S0G5G7|S0G5G7_9DELT DNA gyrase subunit A OS=Desulfotignum phosphitoxidans DSM 13687 GN=gyrA PE=3 SV=1
IEDLIAEEDMVVTVTRSGYIKRNPVTLYASQHRGGKGKTAMGT-IDDFVEHLFVASTHATVLFITNFGKVYQAKVYELPMAGRSSLGKAIVNLLQFEE-E
TLATLLTVNN----CYVVMATRKGRVKKTDLMAYSR-RSGGLIGVKLAPGDELIAAR-TDG-MNVFLGSDGGKVIRFHE--VRATARGSMGVRGMRIP--
SQVVGMEVLA-QQTLLTVTENGYGKRTDVAEYKTQNRGGMGVFSIKTS-K-NGKMVSLALVDT-DELMMVTDKGILIRTDIGGINIISRNTQGVKLINLG
-GKLIGIARLF-
>tr|I5B470|I5B470_9DELT DNA gyrase subunit A OS=Desulfobacter postgatei 2ac9 GN=gyrA PE=3 SV=1
IEDLIAEEDMVVTVTRSGYIKRNPITLYASQHRGGKGKTAMGT-SDDFVEHLFVASTHATFLFITNFGKVYQAKVYELPMAGRSSLGKAIVNLLNFDE-E
KLATVLTVDN----RYVVMATKKGRVKKTELMAYSR-RAGGLIGVTLADGDELIAAR-TDG-QEIFLGSEGGKVIRFNE--VRDMGRGAMGVRGMRID--
ARVVGMEVLG-EETLLTVTENGYGKRSKIEEYKTQARGGKGVFSIKTS-K-NGKMMALALVGN-DELMMITDKGKLIRTDICGINVISRNTQGVRLINLA
-ETLIGIARLP-
>tr|K0YI81|K0YI81_9ACTN DNA gyrase subunit A OS=Slackia piriformis YIT 12062 GN=gyrA PE=3 SV=1
MEDLIAEEDMVVTVTKAGYVKRLPVATYRQQKRGGKGMQGVNL-DNDFVEHLFVASTHSYMLFFSTAGKVYRLKVYELPE-SRHARGTAIVNLLPLAKGE
TISAIIATK-F-EDEFLMFGTEQGMVKKTSMSLYDRTRRDGLIAINLKEGDSLIAVRRVKRGEKVMMVSSAGKAIMWD---ARAMGRDTMGVRGMTVP--
-KVLGMEIA--DTELFVITEKGYGKRTPVSEYPEHHRGGQGVFTITMTE-KKGLLTAMKVVR-ADELMIISEEGVVIRTPVEDVSQ-GRSTQGVRVMNVA
-EKVTAVAIAT-
>tr|D0WHH9|D0WHH9_9ACTN DNA gyrase subunit A OS=Slackia exigua ATCC 700122 GN=gyrA PE=3 SV=1
VEDLIADEEVAVTVTKAGYVKRIPVSAYRQQKRGGKGMQGVNL-ENDFVEHLFVASTHSYMLFFSTAGKVYRLKVYEIPE-SRHARGTAIVNLLPLVKGE
SIAAVIATK-F-EDEYLMFGTEQGMVKKTSMNLYDRTRRDGLIAINLKEDDQLIAVRRVKSGEDVIMVSSAGKAIKWN---VRSMGRDTMGVRGMTVP--
-KVLGLEIA--DTDLLVITENGYGKRTPVSEYPSHHRGGQGVFTIVMTA-KKGNLSAMKVVA-SDELMIISESGIIIRTKAADVSE-GRATQGVRVMNVA
-KKVTAVAIST-
>tr|C7N0K5|C7N0K5_SLAHD DNA gyrase subunit A OS=Slackia heliotrinireducens (strain ATCC 29202 / DSM 20476 / NCTC 11029 / RHS 1) GN=gyrA PE=3 SV=1
VEDLIADEEMVVTMTNAGYIKRLPVTTYRQQKRGGKGMQGVNL-ENDFVEHLFIASTHNYMLFFSSAGKVYRKKVFEIPEG-RHARGTAVVNLL-KDKGE
SIVAAIATK-F--DEFLMFGTKEGMVKKTAMSLYDRTRQDGLIAINLREGDELIAVKRVKPGEKVAMVSSAGKAISWD---VRAMGRDTMGVRGMTVP--
-HVLGLEIASPGKEIFVITERGYGKRTPVEEYP-HHRGGQGVFTITMTA-KKGQLAAMKVVT-EDALMIISEEGVVMRTSVSDIS-LGRATQGVKVMNVD
-KRVSAVAIAP-
>tr|A0A060RBP8|A0A060RBP8_9BACT DNA gyrase subunit A OS=Mucinivorans hirudinis GN=gyrA PE=3 SV=1
PEDFYADEEVVITISHLGYIKRTPLTEYRTQSRGGVGSKGSAT-DEDFIEHIYVTTMHNTMLLFTEKGRCFWLKVYEIPEGSKTSKGRALQNVIAIEPDD
KVRAYINVRT--NNNYIIMCTREGIIKKTSLEAYSR-RTNGVNAITIKEGDQLLEARLTSGKAQVILAAKDGKSIRFE---VRAIGRTAAGVRGMNLEE-
-DLIGMLTVEPKSEILVVSENGYGKRTDIDDYRIQSRSGKGIKTIQITE-KTGKLIAIQSVD-TKDLMIITRSGLTIRMPISEIRLTGRAAQGVKVINLR
-DSIASVVAVP-
>tr|U5Q8E8|U5Q8E8_9BACT DNA gyrase subunit A OS=Bacteroidales bacterium CF GN=gyrA PE=3 SV=1
PEDFYADEDVVITISHMGYIKRTPLNEYRTQNRGGVGAKGSTT-DEDFIENIYVANMHSTMLFFTQKGKCYWLKVYDLPEGSKASKGRAIQNVLNIEPDD
KACAFINVNT--NNNYIVLCTKRGIVKKTSLEAYSR-RTNGVNAITIRDNDELLEATLTNGKNEILLAAREGKCVRFN---VRAIGRTGAGVRGINIT--
-DVIGMICVDPASHVLVVSENGYGKRSLLD-YRVVNRGGKGVKTLNITE-KTGKLIAIKNVT-ENDLMIINKSGLTIRLDVASVRVAGRATQGVRLINIK
-GSIAAVCRVN-
>tr|R5W6K5|R5W6K5_9BACT DNA gyrase subunit A OS=Alistipes sp. CAG:157 GN=gyrA PE=3 SV=1
PEDFYADDEMVITISHMGYIKRTPLAEYRTQHRGGVGVKASAT-DEDFIEHIYVASMHDTMLFFTEKGRCYWLKVYNIPEGTRTSKGRAIQNVIQIEPDD
KIRAYINVRD--ENNYIVMCTREGIIKKTKLEAYSR-RQNGVNAITVKEGDQLIDANLTSGRADIIIAAREGKAIRFP---VRPIGRTGAGVRAITIEG-
-DVVGMICMEPANDILVLSENGYGKRTDLDAYRTTNRGGKGVKTMQVTE-KTGKVVSIQSVS-EYDLMIITRNGTAIRTAASDIRLAGRATQGVKVINLR
-GSIASVMAVP-
>tr|G5H6D0|G5H6D0_9BACT DNA gyrase subunit A OS=Alistipes indistinctus YIT 12060 GN=gyrA PE=3 SV=1
PEDFYADEEMVITISHMGYIKRTPLTEYRTQNRGGVGMKGSAT-DEDFIEHIYVTTMHNTMLFFTEKGRCYWLKVYAIPEGSRSSKGRALQNVIQIEPDD
KIRAYINVRD--DNNYIIMCTKAGIVKKTRLEAYSR-RQNGVNAITIKDGDELIEAKLTTGNSEVLIAAKDGKAIRFN---VRPIGRTGAGVKGITIED-
-DVIGMVCVEPKEDILVVSENGYGKRTDLDDYRITNRGGKGVKTLQITE-KTGKLIAIKSVT-ANDLMIINRSGLTIRIPVGDIRLSGRATQGVKVINLR
-GSIASVIPVP-
>tr|C7H1V9|C7H1V9_9FIRM DNA gyrase subunit A OS=Faecalibacterium prausnitzii A2-165 GN=gyrA PE=3 SV=1
IEDLIAEEQCVYTLTEAGYIKRQLKATYQAQKRGGRGISGMTR-EEDIVQEMFVGSTHDYVLFVTDKGRLFRIKGYTIAES-RTSKGTNIVNLLQLAEGE
KVTNMLCQSN--EGGFVTMVTKQGLIKRTPLEQYANIRKSGLIGIALNEGDALAWTRLTSGHDMLIVATRNGQAIRFN---ARPMGRSGHGVRAIKLA--
-EVVGVCIC--NATILTVTENGKGRRSDIDTYRITARGGKGIRNYDA-S--KDKVAAVKIVD-VDDVLLSSQEGIIIRLHANEIPV-SRYGSGVRVMRLG
-NKVMVLARTD-
>tr|A0A0D8IZL7|A0A0D8IZL7_9FIRM DNA gyrase subunit A OS=Ruminococcaceae bacterium 585-1 GN=gyrA PE=3 SV=1
IEDLIPEEESVFTLTHAGYIKRQPSDTYQAQRRGGRGITALSR-DEDFVEELFLASTHDYILFVTDMGRVYRLKGYQVYES-RTSRGVNIVNLLPLQDGE
QVTSMLRVPN--AEGYLTMVTKAGVIKRTALANYSNIRKNGLIAINLNEGDSLAWTRITSGEDELIVATRNGMAIRIS---ARPLGRTATGVRAIRLK--
-SVVGVGVV--GATVLTVTEEGKGRRTDVRDYRTQYRGGLGIRNYGS----KGHVAGLKVID-TDDIILISLEGIIIRMHVEDINV-SRYGSGVRVMRLG
-GRVVTVARTE-
>tr|D1PRM5|D1PRM5_9FIRM DNA gyrase subunit A OS=Subdoligranulum variabile DSM 15176 GN=gyrA PE=3 SV=1
IEDLIPEETCIFTLTHEGYIKRTTLDTYQAQNRGGRGVQGMTQ-DDDFTEELFVGSTHDYMLFMTDQGRVYRLKGYQVPES-RTAKGSHIVNLLQLQEGE
KVTLMLQQSE--DNTYLTMVTRQGLIKRTPLSQFRNIRKAGLIAIGLNEGDSLVWSHLTGGGDEIIVATHDGAAIHFT---ARAMGRTGHGVRVIRLR--
-YVIGAGVC--GATVLTITEDGKGRRSRVDDYRITKRGGLGIRNYA-----KGGVAGIKIVD-TDDLILISANGILIRLHASDINV-SRYGSGVRVMRLG
-GKVAMVARVD-
>tr|L1NDG2|L1NDG2_9PORP DNA gyrase subunit A OS=Porphyromonas catoniae F0037 GN=gyrA PE=3 SV=1
PEDFYADDEMVITISHLGYIKRTPLTDFRTQARGGVGAKGSDT-DEDFIEYIYSASMHSTMLLFTQMGRCYWLKVYEIPEGTKGSKGRALQNLLNIETGD
RVNAFICVKT--NSHYLLFCTKRGTIKKTLLEAYSR-RTNGVIAIDLRDDDRLVGVSLTDGNSEILIANRHGRAVRFN---VRATGRNAMGVRGMTLDGG
-DVIGMISVA-EESILVVSEHGYGKRSLVEDYRITNRGTKGVKTLNVTD-KTGELVAFEAVT-EHDLMIINRSGITIRIHARDISVQGRATQGVRIIDLK
RGEIASVCRVL-
>tr|C2MB60|C2MB60_9PORP DNA gyrase subunit A OS=Porphyromonas uenonis 60-3 GN=gyrA PE=3 SV=1
PEDFYADEDMVITISHLGYIKRTPLSEFRTQTRGGVGVKGADS-DEDFVEYIYSATMHATMMLFTATGRVYWLRVFEIPEGSKSSKGRHIQNLLDLDEEN
RITAFLRIKT--NTHYLVFATEQGLIKKTLLAHYAN-RKTGVRAINLRDDDQVVSVALSNGNCEIFLANRNGRCVRFN---VRPMGRTATGVRGIRLDDP
-DVVGMVVHRLDETILVISEKGYGKRSRIDDYRITKRGAKGVKTINVTD-KTGQLIDIRAVE-DDNIMIINKSGVAIRLSMEQVRVMGRATQGVKMIDLN
RSEIASICNVV-
>tr|J5VYS4|J5VYS4_9PORP DNA gyrase subunit A OS=Porphyromonas sp. oral taxon 279 str. F0450 GN=gyrA PE=3 SV=1
PEDFYADDDMVITISHHGYIKRTPLSEFRSQARGGVGAKGSDT-DEDFIEYIYSASMHETMLLFTQMGRCYWLKVYEIPEGAKNAKGRALQNLLNIEAGD
RVNAFIRVKT--NSHYLIFCTKRGTIKKTLLEAYSR-RANGVIAINLVEGDQLVGVGLTDGESEILIANRNGRAVRFH---VRAMGRNATGVRGMTLDDG
-DVIGMLTVA-EETILVISEQGYGKRSVVEDYRKTNRGTKGVKTLNITD-KTGELVAIRPVT-EHDLMIINKSGITIRVHARDISVQGRATQGVRIIDLK
RGEIASVCQVL-
>tr|A0A0R2CST7|A0A0R2CST7_9LACO DNA gyrase subunit A OS=Lactobacillus senioris DSM 24302 = JCM 17472 GN=FC56_GL001273 PE=4 SV=1
DEDLIEEEDVIVSLTHNGYIKRLPTTEFKAQNRGGRGVQGMGV-DDDFIEHLVSTSTHDILLFFTDAGKVYRMKGYEIPEYGRAAKGIPIINLLNI-DGE
KIQAVINVA--DVDKDLFFTTLLGTVKKTPVAEFTN-RSNGLKAIHLKDGDQVTNVL-ADD-ENIIIGTHQGYAVSFRA--VRTMGRSATGVRGIRLR--
-DVVGSDILAPDSDVFVISEKGYGKKTPASEYPIKGRGGKGIKTVNVT-E-NGPLAGLTTVKD-EDIMLITDKGVMIRFGIEKVSQTGRATLGVHLIKMD
E-KVATMAKVE-
>tr|A0A0R2GRU9|A0A0R2GRU9_9LACO DNA gyrase subunit A OS=Lactobacillus fructivorans GN=IV48_GL000910 PE=4 SV=1
DEDLIEEENVVITLTHNGYIKRLPTDEFKAQNRGGRGVQGMGV-KDDFIEHLLSTATHDRLLFFTNAGKVYSMKAYEVPEYGRAAKGIPIVNLLNL-GNE
KIQTVISIS--DQDKYLFFTTKLGTVKRTPVSDFLN-RKNGLKAIHLHDGDEVIGVS-VDN-DNMIIGTHLGYAVSFKA--VRSMGRSASGVRGVRLR--
-EVVGAAILTPDSDVFVISENGYGKRTKAADYPIKGRGGKGIKTSNVT-K-NGPLVGLSTVTD-EDIMLITNMGVMIRFAVNNVSETGRATLGVHLIRVD
D-KVATMAVVA-
>tr|A0A0A6RGV4|A0A0A6RGV4_9LACO DNA gyrase subunit A OS=Lactobacillus curieae GN=gyrA PE=3 SV=1
DEDLIEEEDVIVSLTHNGYIKRIPTDEFKSQNRGGRGVQGMGV-DDDFVEHLVSTSTHDVLLFFTDAGKIYRMKGYEIPEYGRSAKGIPIINLLSI-EGE
KIQAVINIS--DTEKDLFFVTTQGTVKRTPVAEFTN-RSNGLKAIHLKDGDEVNNVL-VEE-QNIIIGTHRGYAVSFKA--VRSMGRSATGVRGIRLR--
-EVVGSDILDPESEVFIISEKGYGKRTPAAQYPIKGRGGKGIKTANIT-E-NGPLAGLTTVSQ-EDIMLITNKGVMIRFDVNGVSETGRATLGVHLIRMD
D-KVATMAKVE-
>tr|J9W4D9|J9W4D9_LACBU DNA gyrase subunit A OS=Lactobacillus buchneri CD034 GN=gyrA PE=3 SV=1
DEDLIEEEDVIISLTHNGYIKRLPTSEFKAQNRGGRGVQGMGV-NDDFVEHLVSTSTHDVLLFFTDAGKVYRMKGYEIPEYGRSAKGIPVINLLNI-GNE
KIQAVINVS--DIEKDLFFVTLMGTVKRTPVSDFAN-RSNGLKAINLKDDDQVSNVL-ASE-QNIIIGTHRGYAVSFNA--VRSMGRSATGVRGVRLR--
-NVVGSDILKPDSEVFIISENGYGKRTPAAEYPIKGRGGKGIKTANIT-E-NGPLAGLTTVNE-EDIMLITDQGVMIRFSVEDVSQTGRATLGVHLIRMT
G-KVATMAKVE-
>tr|R7BD18|R7BD18_9FIRM DNA gyrase subunit A OS=Firmicutes bacterium CAG:341 GN=gyrA PE=3 SV=1
DEDLIPVEDCILTLTEKGYMKRQTVDTYKAQNRGGRGVSGMSR-EEDVAKTMFSCSTHDFIMLFTNKGKVFKMKGYEIPES-RTGKGMNIVNILPVEQGE
QITAMVQVP-D-ERSFLCMMTKNGIIKRTSLDQYDHIRKSGIIAINLDEGDELSWVEITDGKRKLVAATHDGMSICFE---ARLIGRTARGVKAITLG--
-YVVGFAIER-GVKLLTVSETGYGRKSEFSDYRVQSRGGKGLLNYRVEK--FGKVANIAAVT-N-DVIMISTDGIIIRMPVDQIST-QRPAKGVKVMRVN
-GKLATISVVD-
>tr|R6HXG6|R6HXG6_9FIRM DNA gyrase subunit A OS=Ruminococcus sp. CAG:177 GN=gyrA PE=3 SV=1
IEDLIPEETCVFTMTNLGYIKRIPADAYTIQHRGGRGVKGMTR-EEDVAKTMFTCSTHDYVMFFTTRGRTYRLKGYEVPE-SRNSKGMNIVNLLPLEAGE
KVSAMIRVP-YP-DAFLCMVTRKGIIKRTSLDAYRNVRKNGVIAINLDDDDELAWVRLTSGNDDLLIATRKGMGIRFN---ARPLGRTARGVKAIELR--
-EVVGMEVLD-AKAVLTVSTTGYGRRSEPSDYRLQSRGGKGTINYRTE--TYGDVAAIAVVD-SEDVIFISSDGIIIRIPVSQIST-ARPSKGVRVMRVS
EGQLVTVACTP-
>tr|R6J008|R6J008_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:217 GN=gyrA PE=3 SV=1
DEDLIPVEDCMLTLTTMGYMKRQTVDTYKAQNRGGKGIMGMSR-EEDVAKTMFTCSTHDYIMLFTNKGKVFKMKGYEIPAS-RTSKGMNVVNLLPLENEE
QISAMVRVP-S-ERQYLCMVTKNGVIKRTEISQYDHIRKTGIIAINLDEGDELSWVEITDGNRNLIVATHDGMSICFK---ARLIGRTARGVRAIQLA--
-YVVGFAVAL-DTRLLTVSETGYGRKSNFDDYRVQSRAGKGLINYHTET--YGKVAMIAPVR-Q-DIIMISQEGIVIRTPVDQISA-KRPAKGVRVMRTT
-EKVITLSVVE-
>tr|A0A078KKZ5|A0A078KKZ5_9FIRM DNA gyrase subunit A OS=[Clostridium] cellulosi GN=gyrA PE=3 SV=1
VEDLIPVEDCVMTLTHFGYIKRQPSSTYHSQRRGGRGVSSLTR-EEDFVEELFVCSTHDYVLFFTNLGRVYRLKGYEVPES-RNSKGVNIVNILPIAQNE
KITEMIKVP---DNKYLVMVTKSGIIKRTPLEEYHT-RKGGIIGILLAEGDELVRVR-TDG-SELIVGTRLGNAIRFKE--ARAMGRASHGVRAIKLE--
-GVVGMSIVR--ATLLSVTENGFGKRVNLDEYHTQSRAGKGLTSYNIN-E-TGAVAGIKIVDT-DDAMLISSDGVIIRINVSEIPIYSRYAQGVHLMRIN
EGHVVTVARSP-
>tr|R5KNK8|R5KNK8_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:678 GN=gyrA PE=3 SV=1
DEDLIPVEECILTLTNMGYMKRMTVDTYKAQNRGGRGIMGMSR-EEDVAKTMFSCSSHDVVFLFTNTGKVFRKKAYEIPAS-RTGKGMNVVNLLPLEKGE
TVSAMVKIP---SRRYLCMVTKKGVIKRTDIDEYRHIRQSGIIAVNLDEGDELAYVEITDGNRKLVVATHNGMSICFN---ARLIGRTARGVRAITLD--
-YVVGFAAS--GYTLLTVSETGFGRKSSFDDYRVQSRGGKGLINYRT-A-QYGKVAMIAPVK-DEDVIMISSDGIVIRTHVDQIST-QRPSKGVKVMRVN
-GKVATISVVD-
>tr|R5YGS4|R5YGS4_9FIRM DNA gyrase subunit A OS=Ruminococcus sp. CAG:488 GN=gyrA PE=3 SV=1
IEDLIPEETCVFTLTDFGYIKRIPMSEYQTQRRGGKGIKGLTR-EDDIVKTMFTASTHDHIAFFTSKGRTFRLKGYEIPES-RTSKGMNIVNLLPLEGGE
TISSMN-CG-G-DYKYLCMFTRNGIIKRSAVTEYANIRRTGVIAITLDEGDELAWVKMTKGNDDIIVATKKGMSIRFN---ARPIGRTARGVKAIELA--
-EVIGVATVE-GKSILTVSETGFGRVSDFDNYRVQSRGGKGLINYHTEK--NGDVAAVTSVS-N-DIILISSDGIIIRIPADGISK-ARPSKGVRVMRVS
-GKIVTLTPVE-
>tr|R9LB38|R9LB38_9FIRM DNA gyrase subunit A OS=Anaerotruncus sp. G3(2012) GN=gyrA PE=3 SV=1
IEDLIPVEDCVITLTHFGYLKRQLMDSYRTQRRGGRGISGMTR-EEDFVEELFVCSTHDYVMFFTSKGRCFRLKGYEVGES-RTSRGTNIVNLLQIDADE
KVTSMIKVS-F-EDQFLVMVTRKGIIKRTPLSQYRNVRKGGLIAIGLDEDDELAWVRLTDGSSELIVATRQGMAIRFD---ARPLSRTARGVKAITLD--
-EVIGMARVR-GALVLTVSENGLGRRSDIGQYRLQSRGGKGIRNYYVEK--NGMVAGVKMVD-D-DIIMITDDGVIIRIPVSEITV-SRYGGGVRVMRVA
-DRVVTLARTP-
>tr|R5A698|R5A698_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:1013 GN=gyrA PE=3 SV=1
IEDLIPQEECVLTMTNFGYVKRQKTDDYHQQKRGGRGVNGMNR-EEDVATEIFVTGSHDYVMFFSTLGRVYKLKCYEVPES-RTSRGMNIKNLLPLQPEE
GISSMIRVT-F-EDKYLVMVTKNGVIKRTRLSAYDTARKGGLIAIDLDEGDELSWVRVTSGQDDLIVATKKGMAIRFH---VRELSRTARGVRVMKLE--
-CIVGMSILR-GGLVLTVTETGFGRLSTPDNYRIQKRGGKGLLNYHTDK--FGDVAAIKVVD-D-DIILISEDGVIIRIAAGSVRV-ARPSKGVRVMKLQ
-GKVVTLARVP-
>tr|R6BDC4|R6BDC4_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:169 GN=gyrA PE=3 SV=1
IEDLIPQEECVVTLTHFGYLKRQPLDVYKTQRRGGRGISGMTR-DEDFVSDIYTCSTHDYLMFFTNKGKVYRIKGYEIPES-RTSRGTNVVNILPLEQGE
KITCVIKTS-I-EDRYYVMVTRNGVIKRTEYNAYTNVRKSGLIAINLDEGDELAWVKITDGHSDVVLATRQGMSIRFH---ARSMGRTARGVKAISLE--
-QVVGMVVLSAAGDILTVSQSGLGRRTDSEEYRLQTRGGKGLRNYYCDK--NGPVAGFEMVD-T-DIILITDSGIIIRIPADQISK-SRYAGGVKVMRVD
-QSIIGIAVTE-
>tr|B0PBP1|B0PBP1_9FIRM DNA gyrase subunit A OS=Anaerotruncus colihominis DSM 17241 GN=gyrA PE=3 SV=1
IEDLIPVEDCVITLTHFGYLKRQPVDAYRTQRRGGRGVSGMTR-EEDFVEELFICSTHDFIMFFTSKGRCFRLKGYEISES-RTSRGTNIVNLLSMDSDE
KVTALIKVT-D-EDRCLVMVTRKGIIKRTPLGAYKNVRRMGLIAIGLDDGDELAWVRQTDGTSELIIATKNGMAIRFD---ARPLSRTARGVKAITLE--
-EVVGMARVRKGATLLTVSESGLGRRTEVSQYRLQSRGGKGIRNYYVDK--NGPVAGVRMVD-D-DVIIITDDGVIIRIPVREITV-SRYGGGVRAMRVS
-ERVVTLARAP-
>tr|R6CWZ9|R6CWZ9_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:242 GN=gyrA PE=3 SV=1
IEDLIPEESCVVTLTRFGYLKRQPLDVYKTQRRGGRGISGMTR-DEDFVSDIYTCSTHDYLMFFTNKGKVYRIKGYEIPES-RTSRGTNVVNILPLEQNE
KITCVIKTS-I-ENKYYVMVTRNGIIKRTEYNAYINVRKSGLIAINLDEGDELAWVKITNGSDDLILATRNGMSIRFN---ARSMGRTARGVKAIALD--
-QVVGMVVAE-GKDILTVSQSGLGRRTDVSEYRIQTRGGKGLRNYYCDK--NGPVAGFEKVD-N-DIILITDSAIIIRIPVDQISK-SRYAGGVKVMRVD
-ESIIGIAAVE-
>tr|H0E9I9|H0E9I9_9ACTN DNA gyrase subunit A OS=Patulibacter medicamentivorans GN=gyrA PE=3 SV=1
IEDLIADQQMVITITQDGYIKSLPLATYRQQRRGGVGVTGMNM-DGDYIEHLFVCSSHDYLLFFSNRGKVYRSKVYELPEASRQSKGRFLRNFL-PREGE
RIQSVLSTR---ETKYLIFATRSGTVKKTELQAYNTIKADGIIAIKVRDDDELVAVR-VDPDDEVVMVSKAGLAVRFSE--ARSMGRDTTGVRGMDVG--
-PKNS--VIAMDLDLLVVTDNGFGKRTLVREYRKTSRGAKGVKTI--TA--KGGLAGALVVREHEGLVFISEAGMVQRTGVKGINRYGRNSQGVKVMNVR
-DRVSAIARIV-
>tr|R5BAK2|R5BAK2_9BACT DNA gyrase subunit A OS=Alistipes sp. CAG:514 GN=gyrA PE=3 SV=1
PEDFYADEDVVITISHLGYIKRTPLTEYRTQARGGVGMKGSAT-DEDFIDHIYIANMHSTMLLFTQSGRCYWLKVYEIPEGSRVSKGRAIQNVLNI-PND
KILAYINVKK--AANNIVLVTKRGVIKKTSLEAYSH-RTAGVNAVNLREGDELVEALLTNGSEQVLIAARDGRCCRFE---ARPMGRNSTGVRGINIE--
-DVIGAINYDPAHTVLVVSENGFGKRTDFDEYRITNRGGKGVKTINITE-KTGKLIAIKNVT-NDDLMIIEKSGLTIRMAVSDIRVAGRATQGVKLINIK
-GSIAAVSTVE-
>tr|R5BLW3|R5BLW3_9BACE DNA gyrase subunit A OS=Bacteroides sp. CAG:1060 GN=gyrA PE=3 SV=1
PEDFYADEDVVITISHLGYIKRTSLTEFKTQARGGVGKKASST-EEDFIEHIYVANMHSTMLLFTDKGMCYRLKVYELPEGSRTSKGRAVQNLLSIDSSD
SIRTYLNVRE--NSHFVTLVTKRGVVKKTTLSEYSN-RNKGIIAINIREGDELLDALLTDGTENILIAAKAGRCCRFN---LRALGRNSSGVRGISIE--
-DVIGAIAHKMGHSILVVSENGFGKRSDYE-YRLTSRGAKGVKTINITD-KTGTLVAIKDVT-ENDLMIITKSGLTIRMAVSEIRIAGRATQGVKLINIR
-GSIAAVCPVA-
>tr|A0A0G0G9I3|A0A0G0G9I3_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWA2_37_10 GN=gyrA PE=3 SV=1
EIDLVPLEETIVTLTTGGYIKRINPATYKIQKRGG-G--VMK--DD-IVEHFLCASTHDNLMFFTDSGKVFQTQVYEIPEA-RVARGRGLLNFL-ESE-E
K--SLVPST--GQAKYLVMVTKNGTIKKTSLEEFEN-R-SGIIAIKLD--DALKK---TD---DIILTTKGGIAI------IRAMGRSAAGVRGIRLKK-
-GVVGMDVIGKKRYLLVVMENGYGKRTDI-QYK-QGRGGAGIKTA---TTKTGGI-MSCVLHGAMDLIVISQHGQVIRTGV-SISL-GR---GVRIMRLE
G-KVASGACLK-
>tr|A0A0G0BT58|A0A0G0BT58_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWA2_33_14 GN=gyrA PE=3 SV=1
EIDLVPLEETIVTLTTGGYIKRINPGTYKIQKRGG-G--MMK--DD-IVEHFLSASTHDNLLFFTDFGKVFQTQVYEIPET-RVARGRGLLNFL-ESE-E
K--SLVPIPNQTQEKYLVMVTKNGRIKKTDLSEFDN-R-SGIIAIKLE--DLLKK---TD---DIILATKNGIAI------IRPMGRSAAGVKGVRLKK-
-GVIGMGVIAKKEYLLVVMENGYGKRTEI-QYK-QGRGGSGVKTA---TSKTGNV-LSYILD-DEDLIVISQKGQVIRSAT-SISI-GR---GVRIS---
------------
>tr|A0A0F9YMS4|A0A0F9YMS4_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWC2_32_10 GN=gyrA PE=3 SV=1
EIDLVPLEETIVTLTTGGYIKRLNPDTYKSQHRGG-G--VMK--DD-IVEHFLTASTHDNLMFFTDSGKVFQTQVYEIPEN-RVARGRGLMNFL-ESE-E
K--SMVPTKGKSADKFLVMVTKDGTIKKTALEEFGN-R-SGIIAIKLD--DLLRK---TD---DIILVTKNGIAI------VRAMGRGASGVRAIKLKK-
-GVIGMDVIPAKEFLLVVMEHGYGKRTEL-QYK-QSRGGSGIITA---TGKTGPV-LSAVLR-QEDLIVISQKGQVIRTDI-SVSL-GR---GVRIMKLD
G-KVASGACIK-
>tr|A0A0J8A580|A0A0J8A580_9ACTN DNA gyrase subunit A OS=Streptomyces regensis GN=gyrA PE=3 SV=1
IEDLIAEEDVVVTITRTGYAKRTKTDLYRSQRRGGKGVQGA-TKQDDIVQHFFVCSTHDWLLFFTNKGRVYRTKAYDLPEGSRNARGQHVANLLAFQPDE
EIAGAIHIP---AD-YLVLATRNGLVKKSRLTDFDS-RSGGLIAINLRE-DELVGAV--SADDDLLLVSAEGQSIRFHE--LRPMGRATSGVLGMRFN-G
-DLLKISVVKPDTFLLVATDGGYAKRTAIEDYPVQGRGGKGVLTIQQD-RKRGRLVGALVVED-DELYAITSSGGVIRTPADDVRK-GRQTKGVRLMNLD
-GTLLTVARNA-
>tr|D2SGE1|D2SGE1_GEOOG DNA gyrase subunit A OS=Geodermatophilus obscurus (strain ATCC 25078 / DSM 43160 / JCM 3152 / G-20) GN=gyrA PE=3 SV=1
MEDLIAEEEVVVTITRTGYAKRTKSDLYRSQRRGGKGVMGA-AKQDDIVDHFFVGSTHDWILFFTNKGRVYRAKAYELPEANRTARGAHVANILAFQPDE
KIAQVMQIK---AP-YLVLATANGQVKKTRLTDFDS-RSGGVIAINLRE-DELVGAA--DPDQDLLLVTRKAMSIRFKA--LRPMGRATEGVRGIALS-D
-DLLSMIVVEEGVDVLVATERGFAKRTGIENYPAQGRGGKGVLTADPK-SRKGNLVGALSVRG-DELYAITSGGGVIRTPVNGVRHKDRATMGVKLMNLP
-DSIVAIARTT-
>tr|A4F5N8|A4F5N8_SACEN DNA gyrase subunit A OS=Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 
MEDLIADEDVVVTLTRTGYAKRTRTDLYRAQKRGGKGVQGA-QKQDDIVSHFFVCSTHDWILFFTNKGRVYRAKAYELPEANRTARGQHVANLLAFQPDE
HIAQVMQIK---AP-YLVLATRNGLVKKSRLTDFDS-RSGGLIGVNLKD-DELVGAV--SADDDLLLVSAEGQSIRFHE--LRPMGRATSGVLGMRFN-G
-DLLAMGVVRPDRYVLVATDGGYAKRTPIDDYPVQGRGGKGVLTIQYD-RKRGRLVGALIVDD-DELYAITSTGGVIRTTAKEVRK-GRQTKGVRLMNLG
-GSVVAVARNA-
>tr|H5WX55|H5WX55_9PSEU DNA gyrase subunit A OS=Saccharomonospora marina XMU15 GN=gyrA PE=3 SV=1
VEDLIAVEDVVVTITRTGYAKRTKTDLYRSQKRGGKGVQGA-TKQDDIVQHFFVCSTHDWILFFTNKGRVYRAKAYDLPEASRNARGQHVANLLAFQPDE
HIAGVIQIP---AP-YLVLATKKGLVKKSRLSDFDS-RSGGLIGINLRE-DELVGAV--SAEDDLLLVSSDGQSIRFRE--LRPMGRATSGVLGMRFN-G
-DLLGISVVKEGTFLLVATDGGYAKRTPIDDYPVQGRGGKGVLTIQHD-HKRGRLVGALIVED-DELYAITSSGGVIRTPAGEVRK-GRQTKGVRLINLD
-GTLLAVARNA-
>tr|C2LUX2|C2LUX2_STRSL DNA topoisomerase 4 subunit A OS=Streptococcus salivarius SK126 GN=parC PE=3 SV=1
TASLIVEEETYVSITRGGYVKRTSPRSFNAST--I---------DD-DLILV-QQKTTQHLLIFTNQANVIYRPIHELPD-----LGEHLSQTITN-SDE
E--YAEILD----GT-YLAATKLGQIKRFERKEFT----KSVKYAKLK-SDFIVT---Q---DDIMIITQKGYAL------V--VGAKAAGVKTINLK--
-DVQAVFVANT-QSFYLLTQRASLKRVATA------RAGRGLQVL----RLPHRF-TAGPVFVPQTLLVTATTGETAEVDL-LLNL---TSNGSFIEGLA
D--VFSAKIIE-
>tr|V6Z3C0|V6Z3C0_STRAG DNA topoisomerase 4 subunit A OS=Streptococcus agalactiae LMG 14747 GN=parC PE=3 SV=1
AASLIVEEETFVSVTRGGYIKRTSPRSFNAST--V---------DD-DLIFY-IQKTTQHLLLFTNKGNVIYRSVHELPD-----IGEHLSQNITN-HDE
E--YAEILD----GT-YMAATQEGQIKRFERKDLS----KSVKFAKLK-TDKVVA---T---ESIMVVTHKGYAL------V--VGPKAAGVKAINLK--
-DVQSVFLSNS-SSFYLLTQRGSLKRMKTS------RAGRGLQVL----RLPHRF-QAGPIYVQVTLEIMSNTGEIREIDL-ALPL---TSNGSFVSETI
E--VLSAKMV--
>tr|R5FQP0|R5FQP0_9FIRM DNA gyrase subunit A OS=Coprobacillus sp. CAG:698 GN=gyrA PE=3 SV=1
DADLIPVEDVIITVTKKGYVKRLTVDTYRAQNRGGKGITGAKL-DDDFIEKVLFTSSHDNLLFFSSLGKVYKLRAFQIPVG-RNAKGLPIVNLLNFEEGE
KLATVLNVDE--TNGYFIFATRQGIVKKTEISAFENIRTNGIRAILLNDGDELFKVDITDGEKDIILGASNGKGIRFS---IRPMGRISAGVRGLKIE--
-KMIGMAIV--GDEIVIVTEKGYGKRTNVDAFRVQVRGGKGVKALNITN-KNGKMIALTTVR-DEDLLVITDKGMVIRTHLEQILT-GRDTQGVCIIKLN
-GVAASIAIVP-
>tr|A0A0B3AI93|A0A0B3AI93_9ARCH DNA gyrase subunit A OS=archaeon GW2011_AR1 GN=gyrA PE=3 SV=1
EKDLVQDKEVVISITDKGYAKRMDVQTYKEQKRGG-G--INN--GD-FTKQILTCSTHDYLMFFTSRGRVLWLKTYDIPEE-RYGKGKALINLLGL-E--
R--KVISV---NFDDFLIMATKKGVVKKISLSYFSN-R-SGLKAINLPL-DDLIG---VQ---EISLATKDGKAI------VRSMGRSSYGVTGIKLS--
-KVVSLEVLET-EAIFTITKNGYGKRTAV-DYR-TARAGKGVINL---NEKTGNV-NAISVN-SDSIIITTAKGQVIRMSL-NIRI-GR---GVRILKLQ
E-YVTDVVKVH-
>tr|G9ZJQ1|G9ZJQ1_9GAMM DNA gyrase subunit A OS=Cardiobacterium valvarum F0432 GN=gyrA PE=3 SV=1
LEDLIAEEDRVITLSHEGYIKAQPLSDYEAQKRGGKGSATA-VKDEDFVEQLIIANTHDTMLCFTNRGKVYWLKVYELPQAGRNAKGKPIVNLLPFE-GE
RLNAVLTTREYPEDRYLIFATKSGTVKKTPLSDYSRPRSIGIIAINLREDDELVDVALTDGSRDIMLFSDAGKAVRFPEASVRSMGRDATGVRGMNLDDQ
R-VIALCVVA-NGDILTVTENGYGKRTPIADYPQKGRGTKGVISIACSE-RNGRAVSALQVQEDEHIMLVTDNGTLVRTRVAEISTSGRNTQGVRLIRTS
DSKLIAVAKIV-
>tr|A5EW68|A5EW68_DICNV DNA gyrase subunit A OS=Dichelobacter nodosus (strain VCS1703A) GN=gyrA PE=3 SV=1
MEDLIAEEDRVITLSHEGYIKAQPLSDYEAQRRGGKGSVTA-IKDQDFVEQLFIANTHDTMLCFSNKGKVYWLKVYELPHASRNAKGKPIVNLLPFE-DE
RLNAILTTREYPEDLYLFFATQNGTVKKTPLSEYSRPRANGIIAINLRDDDQLVDVELTNGERNIMLFSNAGKAVRFSEETVRSMGRAAGGVRGMRLEA-
-QVIALCVLKDQGDILTITENGYGKRTPTADYPQKGRGTKGVISIMCSE-RNGNAVYAIQVCEDEDIMLVTDNGTLVRTRVCEISTSGRNTQGVRLIRTA
ESKVIAAAKII-
>tr|A0A0J9DZ77|A0A0J9DZ77_9RALS DNA gyrase subunit A OS=Ralstonia sp. MD27 GN=gyrA PE=3 SV=1
TEDLITPQDLVVTLSHSGYMKSQPISEYRAQKRGGRGQAAA-TKEDDWIDTLFVANTHDYILCFSNRGRLYWLKVWEVPAGSRNSRGRPIVNMFPLS-GE
KINVILPVKQF--QHFVFMTTSKGTVKKTALTDFSNPRKAGIIAVDLDEGDFLIGAAITDGQHDVMLFSDAGKAVRFDENDVRPMGRQARGVRGMNLE--
EGVIAMLVAPAIGSVLTATENGYGKRTPISEYTRHGRGTKGMIAIQTSE-RNGKVVAAALVAPEDEIMLITTGGVLIRTRVDEIREMGRATQGVTLINVG
EGKLSGLQRVV-
>tr|A0A0G0VW90|A0A0G0VW90_9BACT DNA gyrase subunit A OS=Microgenomates (Curtissbacteria) bacterium GW2011_GWA2_41_24 GN=gyrA PE=3 SV=1
EEDLIANESTIVTVTVGGYVKRQDLSSFRTQRRGG-G--SIT--ED-TVAHLFAAYTHDNLLFFTNIGRVFQLKVYDLPES-RVSKGVAIVNLL-DQN-E
K--SILPVK--SNHKYVLMATKNGVVKKTAISQYES-R-SGIIAIKLA--DHLRW---TN---LIFLISKHGLSI------VRPMARDTMGVRGIKLKP-
-NLIGMDVIDK-ADLLVITDKGIGKKTQV-AWP-QLRGGVGVKAA---TEKTGEV-CAQILT-DEALILTSQKGQVMRTTL-SIPR-TR---GVIIMRLS
--KVAATTVIQ-
>tr|A0A0G1U5W0|A0A0G1U5W0_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWA2_47_10b GN=gyrA PE=3 SV=1
VEDMIPEEEHIVLMTRDGYLKRLKPKEFRAQKRGG-G--VGE--ED-VVLNFATCGTHDTLLFFSTTGKVYETKTYEIPES-RIAKGKPIVNFL-AAS-E
E--SFIAVP--GKDAFLVMATKHGIIKKTDLHAFLG-R-SGIIAMKLR--DVLGW---AD---DCMLFTKRGQAI------IRTMGRQAQGVRGIKLAS-
-GVIGCDTVSKDLFVFSISAAGYGKKTMV-EFK-QSRGGSGVKTM---NEKTKPV-AVKILD-NEQYITISQKGKTLRSYI-ELPT-GR---GVRIMRLE
G-RLSAVAVL--
>tr|A0A0G0TMM1|A0A0G0TMM1_9BACT DNA gyrase subunit A OS=Microgenomates (Curtissbacteria) bacterium GW2011_GWA1_40_9 GN=gyrA PE=3 SV=1
EEDLIPNEPTIVTFTEGGYVKRQDPASFRTQRRGG-G--SIT--ED-VVSQLFVTHTHDNLLFFTDRGRVFQLKVYDLPES-RVAKGGAVVNLI-DMG-E
K--SVLPVK--PKPQFVIMATKHGVVKKTAISAYES-R-SGIIAIKLT--DQLSW---TD---TVLMISKRGMSI------VRPMARDTMGVRGIKLKP-
-GLIGMDALDK-AELLVITEKGIGKKTLV-AWP-QLRGGVGVKAA---AEKTGNV-TAQILT-DESLILTSQKGQVMRTTI-SVPR-TR---GVIIMRLT
--KIAAATIVK-
>tr|K2AN04|K2AN04_9BACT DNA gyrase subunit A OS=uncultured bacterium (gcode 4) GN=gyrA PE=3 SV=1
EEDLIANEATIVTITVGGYVKRQDIGSFRTQRRGG-G--SIT--ED-TVAHLFAAYTHDNLLFFTDKGRVFQLKVYDLPES-RTSKGVAIVNLL-DSD-E
K--SILPVK--NNYKYVLMATKNGVVKKTEINQYAS-R-SGIIAIKLS--DQLRW---TN---IVFLVSRHGMSI------VRPMARDTMGVRGIKIKT-
-GLIGMDVIDK-ADLLVVTDKGIGKKTQG-AWP-QLRGGVGVKAA---TDKTGEV-CAQILT-DEALILTSQKGQVMRTTL-SIPR-TR---GVIIMRLG
--KVAATTVIQ-
>tr|A0A0G0DJY8|A0A0G0DJY8_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWA1_36_12 GN=gyrA PE=3 SV=1
EEDLIANDPTIVTITQGGYVKRQDIGSFRTQRRGG-G--SMK--ED-TVAQLIACQTHDDLLFFTDRGRVFKLKVWELPDS-RTAKGVAIVNLL-EQN-E
K--STLKVS--KSSRFVTMATKNGVIKKTEIKAYEA-R-SGIIAIKLS--DALRW---TD---SVFLVSKKGMSI------VRPMARDTMGVRGIKLKP-
-GLIGTDVIAKKADLIVITARGIGKKSNI-AWP-QLRGGVGVKAA---ADKTGNV-NAQILT-DEGLILTSQKGQIMRTTL-SVPR-TR---GVILMRLT
D-RVSAATVIQ-
>tr|W0R6H5|W0R6H5_BIBTR DNA gyrase subunit A OS=Bibersteinia trehalosi USDA-ARS-USMARC-190 GN=gyrA PE=3 SV=1
LEDLIAPEDVVVTLSHAGYVKYQPLSDYEAQRRGGKGSAT-KMKEDDFIEKLLVANTHDVILCFSSRGRVYQLKVYQLPQASRAARGTPIINILPLE-GE
RITSILPIQ--SEDKFVLMATASGIVKKVTLDAFSN-RSNGLIALNLRDGDELIGVDITDGESEIMLFSAQGRVVRFKESAVRAMGRTATGVRGMKLATL
NKVVSLVIPKNEGEILTVTQNGYGKRTKLAEYPTKSRNTKGVVSI--NV-RNGKVVAAVQVI-SDQIMLITDGGTLVRTRVGEVSLVGRNTQGVRIIRTI
-GSVVGLERIA-
>tr|A0A0H4HZY0|A0A0H4HZY0_9ALTE DNA gyrase subunit A OS=Marinobacter psychrophilus GN=gyrA PE=3 SV=1
VADLIDEEELVVTISHSGYAKTQAVEDYQAQRRGGRGAATS-MKDEDFVEKLLVANSHDTILCFSNRGKVYWLRVFEIPRASRASRGRPMVNILPLD-GE
RITTFLPVRDYPEDQFVLMATSAGVVKKTPLPNFSRPRSSGLIALSLDEGDTLIGAAITDGSAEIMLFSTAGKAVRFKEEAVRPMSRTARGVRGIRMA--
EGVVSLIIPQDNAVLLMASEHGYGKRTNLDEFPTYGRGSQGVIAMQCSD-RNGNLVTALQLFDGDEMMLISDKGTLVRTRTDEVSVLSRNTQGVRLIKLS
EDRLVGVERIA-
>tr|M1YWA4|M1YWA4_NITG3 DNA gyrase subunit A OS=Nitrospina gracilis (strain 3/211) GN=gyrA PE=3 SV=1
IEDLIADEDVVVTYSRGGYIKRQLIDNYRAQKRGGKGIKGMAV-EEDVVHQVFVASNLDYLLVFTNLGRVHWLKVYHIPEASRIAKGKSIANLIQLQP-E
KIASILTVDD----KFITCVTERGIVKKTSMDAYSR-RQGGIIGLTLDEGDRVITAL-SDG-QHILMATRSGMAIRFDE--VRPIGRTGRGVTGIRFK--
DRVVGAEIVE-GKHLLAVAENGLGKRTPIDDYPVQGRGGRGVITLRCN-E-TGHLVGVEQVQD-DELLVVTSRGNIVRMEVSEISVMGRNTQGVRLVRME
-GQIVGFEKLE-
>tr|M7D750|M7D750_9ALTE DNA gyrase subunit A OS=Marinobacter santoriniensis NKSG1 GN=gyrA PE=3 SV=1
IADLIDEEDLVVTISHGGYAKTQAVEDYQAQRRGGRGAATS-MKDEDFIEKLLVANSHDTILCFSNRGKVYWLRVFEIPRGSRGSRGRPMVNILPLD-GE
RITTFLPVRDYPEDQFVLMATSNGVVKKTPLPNFSRPRSSGLIALNLDDGDTLVGAAITKGDAEVMLFSSAGKAVRFAEDQVRPMSRTARGVRGIRMP--
EGVVSLIIPEEGGVILTASEHGYGKRTAIDEFPTYSRGSQGVIAMQCSE-RNGDLVTALQLFDGDEMMLISDKGTLVRTRTDEVSVLSRNTQGVRLIRLA
EDRLVGVERIA-
>tr|N6VW28|N6VW28_9ALTE DNA gyrase subunit A OS=Marinobacter nanhaiticus D15-8W GN=gyrA PE=3 SV=1
IADLIDEEDLVVTISHNGYAKTQPVEAYQAQRRGGRGSSTT-MKEEDFIEKLLVANSHDTILCFTNKGKVYWLRVFEIPQASRAARGRPMVNILPLD-DE
RVTTFLPVRDYPEDHYVLMATSAGVVKKTPLPNFSRPRSNGLIALSLDEGDTLIGAAITAGESEVMLFSSAGKAVRFKEEQVRAMGRTARGVRGIRMP--
EGVVSLIIPEESGMILTASENGYGKRTQIEEFPAYSRGSQGVIAMQCSE-RNGNLVSATQVFESDEMMLISDKGTLVRSSTEEVSVLSRNTQGVRLIRLT
EDRLVAVQRIA-
>tr|A0A0F9W2T1|A0A0F9W2T1_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_0021480 PE=3 SV=1
MEDLITEEDRVVTISRSGYAKSQPLTDYHAQRRGGMGAAAA-VKDEDVVEHLLIASSHDTLLCFSSAGKVYWLRVFNIPLASRTSRGRPLVNILPLE-GE
RITSMLPIREYTEGYFIFMATAMGTVKKTSLTSFSRPRSVGLRAIELDEGDRLVGTALTDGQRDIMLFGSGGKVLRFNEAGVRTMGRTARGVRGIRLAAQ
E-MIALIIPE-GHQVLTVSENGYGKRTDVAEFPVYGRGGQGVIGMQTSE-RNGALVGAVQVADGGQIMLISNKGTLVRIRVDEVSVLSRNTQGVRLIKLK
KDLLVGVEPVA-
>tr|A0A0F5JUU3|A0A0F5JUU3_9BURK DNA gyrase subunit A OS=Burkholderia andropogonis GN=gyrA PE=3 SV=1
TEDLITPQDMVVTMSHGGYVKSQPLSEYAAQRRGGRGQATQ-MKEDDWIETLFIANTHDYILCFSNRGRVYWVKVYEVPQGSRNSRGRPIVNMFPLQ-GE
KINVVLPVREF--DRYVFMATALGTVKKTPLEQFSRPLRKGIIAVSLDEGDYLIGAAITDGKHDVMLFSDAGKAVRFDEGDVRAMGRDARGVRGMQLE--
DGVIAMLVAENQQSVLTATANGFGKRTPIEEYTRHGRGTKGMIAIQTSE-RNGKVVAATLVEPSSELMLITTSGVLIRTRVSEIREMGRATQGVTLISLD
EGYLSGLQKVV-
>tr|A0A0B2W5A7|A0A0B2W5A7_PECCA DNA gyrase subunit A OS=Pectobacterium carotovorum subsp. actinidiae GN=gyrA PE=3 SV=1
IEDLINQEDVVVTLSHQGYVKYQPLSDYEAQRRGGRGSAA-RIKEEDFIDRLLVANTHDTILCFSNRGKVYQIKVYQLPEASRGARGRPIVNLLPLE-NE
RITAIL--P--EEGHHIFMATVNGTVKKTALSEFKN-RSNGIIAIKLNESDELIGASLTSGKDEVMLFSAEGKVVRFSEDAVRSMGRNAAGVRGIRLS--
-SVVSLNIIEKTGDILTVTQNGFGKRTAVSEYPTKSRATKGVISI--SE-RNGKVVGAVQVE-IDQIMMITDAGTLVRTRVSEVSIVGRNTQGVRLIRTA
-DHVVGLQR---
>tr|A0A0N7IHV3|A0A0N7IHV3_9SYNC DNA topoisomerase OS=Synechocystis sp. PCC 6803 GN=AOY38_02700 PE=4 SV=1
FTPQTPPAEAFLSINLQGEIAWHPEELTSAN-------------FE-PLDQQFSIQGRETLIVIGDHGKAFPVAIADIPPL-AV-TRIPLLQILPKSA-T
-TVFQGFLP--EQPQDLLLVSQQGRVKLLAGQELQE-G-RGLSLMKLK--DLLQF---TS---NLVIATSNGRLL------LTCSSPSAQGQE-MRLR--
-TLVGVLMASP--RVLLLTQAGYGKQLDL-SVR-GNFGELGTTVM--TKA---DL-TMVAANQSSTYDFYSNQQRLHSVQA-QFQP-GK---GDRLVDLN
G-HLITQVAHL-
>tr|A0A0B8ZVD3|A0A0B8ZVD3_BRELN DNA topoisomerase (ATP-hydrolyzing) OS=Brevibacterium linens GN=AE0388_0125 PE=4 SV=1
ANLKIADSPCRVLLSTSGRIARTSDAAPLA---------R----SHDALVSEIVTTTQGKVGAITTTGRLHMVDVVDLPAP-PAA-----IAYAA--N-E
K--GLVDLD------EFVLGTAGGVVKRVSVAGRPN---NEWEAITLK-KDSVVG---E--DSLSVFVTSNAQLL------L---GWNASGVAGIKVAD-
-AVIFFGMTPKSFAVVTIASGESIKVSEFS-----GRATSGVRAH--LGEE---S-PQAAA--GGARTLPDGTGSPLESKIVDH--P--AKSGTKAGR--
Q---ASLDELD-
>tr|K9B619|K9B619_9MICO DNA topoisomerase (ATP-hydrolyzing) OS=Brevibacterium casei S18 GN=C272_00775 PE=4 SV=1
ENLRIADAPTRVLLSTSGRIARTSDAAVLA---------R----SHDALVSEVVATTQGKVGALTSTGTLHLIDVVDLPAP-PGA-----VAYAA--N-E
K--GLIDLE------EFLLGTAEGVVKRVSVAGRPN---SEWDAIALK-KDTVIG---R--ASLAVFVTSAAQLL------L---GWNASGVAGIKLGE-
-AAIFFGAVPRSLSVVTIASGESIKVSEFV-----GRATSGVRAH--LGEE---S-PQAAA--GGARTLPDGTGSPLESKIVVT--GG-GDSGAPQAA--
G---ASLDGLD-
>tr|K6ULW7|K6ULW7_9MICO DNA topoisomerase (ATP-hydrolyzing) OS=Austwickia chelonae NBRC 105200 GN=AUCHE_05_05200 PE=4 SV=1
APLEIADDPCWVLMSSTHLLARTTGADEFG---------D----KHDAIVSRVRSTARGEVGVATSAGRILRLSVLELPTP-PTH-----LGFLD--D-E
W--CLVSL---EDSPGLAVGTAQGVVKRVTC-DYPS---ADWEYISLK-GDRVVG---A--TDHLVFVTRRAQLL------V---GRPAGGMAGIKLGG-
-DVIWFGAVDPGSVVVTSAGAESLKVAPFT-----GRATGGVRCQ--LGER---F-PARAAT-GSPIVLPDGSGQPAPAAIAGGTTGGSAARGRQSSP--
V---SPIPGLA-
>tr|L0EVF2|L0EVF2_LIBCB DNA gyrase subunit A OS=Liberibacter crescens (strain BT-1) GN=gyrA PE=3 SV=1
DEDLIAREDMVVTVSHLGYVKRVPLSAYRAQRRGGKGRSGMATRDEDFVTRLFIANTHTPVLFFSSLGVVYKEKVWRLPVGMPQSRGKALINILPLKQ-E
RMTTIMPLP---VNLDVMFSTTPGTVRRNKLSDFVHVNRNGKIAMKLEE-DEIVSVE-T-E-HDVLLTTEFGQCIRFPN--VRVSGRNSVGVRGISLA--
-DVISMAIISHEQFILTISEKGFGKRSSSYDFRISGRGGKGIRVTDF--TEIGALVAAFPVK-KDQIMLVSNGGQLIRVPVEGIRVSSRATKGVMIFFTA
-D-VVSVECIN-
>tr|A0A0A0JGK0|A0A0A0JGK0_9MICO DNA gyrase subunit A OS=Knoellia flava TL1 GN=gyrA PE=3 SV=1
MEDLIPEEDVVVTITRGGYAKRTKVDAYRSQKRGGKGVKGA-QRGEDVVAHFFTTTSHHWLLFFTNLGRVYRAKAYELPDAGRDSKGQHVANIMAFQPDE
HIAQVLALR---SP-HLVLATRNGLVKKTPLSQYDS-RSGGLIAVNLRDGDELVGAG--SSMDDLLLVSRKGQSVRFHA--LRPMGRSTSGVTGMKFR--
-DLLSMSVIEE-PDVFVVFESGLAKRSKASQWNVKGRAILGVAVAKQT-E-GGDLVGALTVSD-DEVMVVFERGNIVRSRVDEVRL-GRNTAGVWFAKPG
-NAIVGVARNA-
>tr|N0DZQ9|N0DZQ9_9MICO DNA gyrase subunit A OS=Tetrasphaera elongata Lp2 GN=gyrA PE=3 SV=1
MEDLIPEEDVVVTITRGGYAKRTRVDQYRLQGRGGKGVRGA-SRGEDLVEHFFATTSHHWLLFFTNLGRVYRAKAYELPDAGRDAKGMHVANIMAFQPGE
QIAQVLALK---AP-YLVLATKSGVVKKTRLTEYDS-RSGGLIAVNLRDGDELVGVD--SAADDLLLISRKGMSVRFHA--LRPMGRSTTGVTGMKFK-A
-DLLSMSVIRE-PDVFVVFENGMAKRTASSEWDAKGRATLGVKVANLT-D-NGDLVGGLTVDN-DQVLVVFAKGNVVRMAVQPVTR-GRNTQGMGFAKPG
-GSVVAVARNV-
>tr|A0A094PB93|A0A094PB93_9ACTN DNA gyrase subunit A OS=actinobacterium acAMD-5 GN=gyrA PE=3 SV=1
HEDLIAVEPIVVTLSADGYIKRTKAVLYRSQKRGGRGVKGA-AKHDDVITNFFVTTTHHWILFFTDRGRVFRVKAYELTDTGRDARGQHVANLLSLAPDE
HVVEVLDLR---AK-YLILATRGGVVKKSRLTDYDS-RSTGLVAITIRD-DGVVSAQ--NDEDDLLLVSKMGYSVRCHA--LRPMGRTAGGVIGIRFK-E
-DLLKMEVATPDSFVVTVTEGGWAKRTSIEEWNAKGRGTQGVRAMRLV-E-RGGLAGALICAQ-DEIFAIASNGVVIRTRVDEIRA-GRDTMGVSFMKVG
-DQVVAVARSR-
>tr|A0A0Q9SZF9|A0A0Q9SZF9_9MICO DNA gyrase subunit A OS=Phycicoccus sp. Soil802 GN=ASG91_04005 PE=4 SV=1
MEDLIPEEDVVVTITRGGYAKRTRVDAYRSQGRGGKGVRGA-SRGDDMVDHFFTTTSHHWLLFFTNLGRVYRAKAYELPDSGRDAKGQHVANLLAFQPDE
KIAQVLDVR---QP-YLVLATKNGLVKKTRLADYDS-RSGGLIAINLKEGDELVAAD--SATDDLLLVSRHAQSVRFHA--LRPMGRATSGVTGMRFR--
-DLLSLSVIHE-PDVFVVFENGMAKRSPASDWNAKGRGGLGVAVAKIT-E-NGDLVGALTVSD-DEVLVIMGKGNIVRMPVSPVTR-GRNTQGMKFANPG
-GTVVALARNP-
>tr|A0A0Q9KNM2|A0A0Q9KNM2_9MICO DNA gyrase subunit A OS=Knoellia sp. Soil729 GN=ASG74_10750 PE=4 SV=1
MEDLIPEEDVVVSITRGGYAKRTKVDAYRSQERGGKGVKGA-SRGEDVVAHFFTTTSHHWLLFFTNLGRVYRAKAYELPDASRDSKGQHVANIMAFQPDE
QIAQVLAIK---ES-YLVLATRNGLVKKTRLSEYDS-RSGGLIAVNLREGDELVGAE--SSADDLMLVSKKGQSIRFHA--LRPMGRSTSGVTGMKFR--
-GLLAMSVIED-PDIFVVFENGMAKRSAASDWRIKGRAILGVAVANIT-E-NGDLVGALTVGG-DDVLVVFAKGNVVRVPSSKVSR-GRKTQGVIFAKPG
-KAIVGVARNA-
>tr|W6K2U2|W6K2U2_9MICO DNA gyrase subunit A OS=Tetrasphaera australiensis Ben110 GN=gyrA PE=3 SV=1
MEDLIPEEDVVVTITRGGYAKRTRVTEYRSQRRGGKGVRGA-QRGEDVVEHFFTTTSHHWLLFFTNLGRVYRAKAYELPDAGRDAKGQHVANLLAFQPDE
KIAAVLAIR---AP-YLVLATRNGLVKKTRLAEFDS-RSGGVIAINLREGDELVGAS--SNVDDLLLVSRKGQSARFNT--LRPMGRATSGVTGMKFR--
-ELLSLSVIPA-PDVFVVFESGLAKRSKSSEWTAKGRGILGVAVAKLS-E-GGDLVGALTVDT-DEVLVVMERGNIVRSRVAEVRL-GRNTMGVSFATPR
-GAIVAVARNS-
>tr|A0A0Q9MJT8|A0A0Q9MJT8_9MICO DNA gyrase subunit A OS=Tetrasphaera sp. Soil756 GN=ASG78_01275 PE=4 SV=1
MEDLIPEEDVVVTITRGGYAKRTRVDAYRAQKPGGRGVRGA-QRGEDMVEHFFATTSHHWLLFFTNLGRVYRAKAYELPDAGRDSKGQHVANLLAFQPGE
EIAQVLAIR---AP-YLVLATRGGLVKKTRLSEYDS-RTGGLIAVNLRDDDELVGVG--SPSDDLLLVSRKGMSVRFHA--LRPMGRGTSGVTGMKFR--
-DLLAMAVIAD-PDVFVVFENGMAKRTSATEWNAKGRATLGVAVAKIT-D-NGDLAGALTTTD-DELLIVFEKGNIVRATTSGIAP-GRNTQGVILVKPP
-GRVKAVARNP-
>tr|A0A077LUF6|A0A077LUF6_9MICO DNA gyrase subunit A OS=Tetrasphaera japonica T1-X7 GN=gyrA PE=3 SV=1
VEDLIPEEDVVVTITRGGYAKRTRVDAYRAQGRGGRGVRGA-QRGDDLVEHFFTTSSHNWLLFFTNLGRVYRAKAYELPDAVRDAKGQHVANLMAFQPGE
QIAQILDLR---AP-YLLLATRSGLVKKTRLAEYDS-RSGGLIAVNLREGDELIGAA--RAEDDVLLVSRKAQSVRFHA--LRPMGRATSGVTGMRFR--
-GLLAMSIIPA-PDVFVVFENGMAKRSPASDWNAKGRGIYGVAVAKIT-E-NGDLAGALTVGD-DEVLVVMGKGNVVRMKVDSVTR-GRNTQGMKFANPG
-DAVVAVAKNP-
>tr|A8YK16|A8YK16_MICAE DNA topoisomerase (ATP-hydrolyzing) OS=Microcystis aeruginosa PCC 7806 GN=IPF_1227 PE=4 SV=1
FTPQEPPENAILLLDAEDKISWTTPEER----------------RD-LIIYQQAIEKQENFLVILDNAKAYPISILEVPPQ-GN-QPVLISSLLTKTS-E
-AVNQFFLT--QKNQELLLLSQQGRIKRLSINELEG-G-RGLSLMKLK--DRLYA---H----DLAIATSSGRVL------LPIMGKSAQGLA-LRLR--
-GLAGCVSLPH--NLLLISGLGYGKRLAI-NLR-SQLGDLGSPAL--VKQ---DL-AMVAARI---VLLSTNQERKLPLEV-TVTV-GK---GSQLVKLN
T-KIIKAQLLH-
>tr|A0A0D5LU85|A0A0D5LU85_9RHIZ DNA gyrase subunit A OS=Martelella endophytica GN=gyrA PE=3 SV=1
DEDLIAREDMVVTVSRNGYIKRVPLTTYRAQRRGGKGRSGMSIRDEDFVTRLFVANTHTPVLFFSSRGIVYKEKVWRLPIGTPQSRGKALINMLPLQQ-E
AITSILALP---AELDVMFATTRGTVRRNKLSDFVQVNRNGKIAMKLDDNDRILSVW-T-P-DDVLLTTAMGQAIRFPA--IRVAGRNSIGVRGIGLA--
-DVISMTIVSHEQFILTVTEKGFGKRSSSYDFRISGRGGKGIRATDT--TEIGKLIAAFPVL-GDQIMLVTNAGQLIRVPVYDIRIASRTAKGVTVFKTG
-D-VVSVEVIS-
>tr|W6RCT8|W6RCT8_9RHIZ DNA gyrase subunit A OS=Rhizobium sp. LPU83 GN=gyrA PE=3 SV=1
DEDLIAREDMVVTVSHLGYIKRVPLTTYRAQRRGGKGRSGMTTRDADFVSQLFVLNTHTPVLFFSSRGIVYKEKVYRLPIGTPTSRGKALINMLPLES-E
RITTILPLP---DKLDVMFSTTRGTVRRNKLSDFVQVNRNGKIAMKLEEGDEILSVE-T-E-DDVLLTTALGQCIRFPD--VRVAGRNSIGVRGINLG--
-DIISMTIVGHEQYVLTVSEKGFGKRSSSYDFRISGRGGKGIRATDT--TEIGELVAAFPVN-GDQIMLVSDGGQLIRVPVGGIRVASRATKGVTIFSTA
-D-VVSVERIS-
>tr|A0A0G0RI21|A0A0G0RI21_9BACT DNA gyrase subunit A OS=Parcubacteria (Falkowbacteria) bacterium GW2011_GWA2_39_24 GN=gyrA PE=3 SV=1
VEDLVPNEEVVVMMTRDGYIKRLTRDTFKVQGRGG-G--ILT--ED-GVEFMFSTMTHDDILFFTSKGRVFQLKTHEIPAQ-RTAKGQAIVNFL-QPQ-E
R--SVLPLK---DYKFLFFATEKGLVKKVAIDAFNN-R-SGLIAIKLK--DKLIW---TD---TIQLITANGQAI------VRDMGRNAAGVLGIRLRK-
-NVVGMGVVNGNYQVLGVMSKGFGKRTPL-LYK-QGRGGSGLKTA---TPKTGPA-NAYVVN-DKDLIIISAQGQVIRLPF-TVKK-GR---GIKLMSFK
K-KIAGVTWL--
>tr|A0A0G1EV44|A0A0G1EV44_9BACT DNA gyrase subunit A OS=Parcubacteria (Falkowbacteria) bacterium GW2011_GWF2_43_32 GN=gyrA PE=3 SV=1
MEDLVPNEETVVMMTRDGYIKRLEPDTFKVQARGG-G--MLT--ED-TVEFMFSSQTHNDVLFFTTKGRVFQLKVYEIPQS-RVAKGTPVVNFL-QIG-E
Q--SILPLD--VFSKYLFFATAKGLVKKVELGAFAN-R-NGLIAIKIR--DKLIW---TD---HIQIITAKGQAI------VRDMGRGAAGVHGIRLHK-
-DIIGMGIAKTNYQILTIMANGFGKRTDF-AYK-QGRGGSGIKTA---TAKTGDT-NAFLVN-DRDLVVVSEKGQVIRTPF-SVSV-GR---GVRVMRFK
E-QVAGVTWV--
>tr|A0A0F9Z305|A0A0F9Z305_9BACT DNA gyrase subunit A OS=Peregrinibacteria bacterium GW2011_GWF2_33_10 GN=gyrA PE=3 SV=1
IKDVVPNSDMVIMLTAQNYIKRISSDTFKNQNRGG-G--ILT--ED-AIIICRFAKNHDEMLFFTNKGRVFKLPVYEIPES-RIAKGQAIVNIL-QQE-E
R--AMLNDD--SLEKYFFMSTKRGTVKKTEISNFQN-R-TGIIAINIR--DELKW---CN---KIVLVTKNGKAV------VRSMGRASTGVRGVRLKT-
-DVVEMDIVENEAKLLVVMENGLGKMSNI-SYR-TARGAGGVKTA---SPKTGKI-GAKIIE-NPDIVLISKNGQTIRMAI-DIPS-GR---GVHIMRLN
--KVVSFSLIN-
>tr|A0A0G0JFX6|A0A0G0JFX6_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWE2_38_18 GN=gyrA PE=3 SV=1
VEDLVPNEEAVVVMTRDGYIKRVPPETFHVQGRGG-G--ILT--ED-MVEFMFTIMTHSDVLFFTTKGRVFQLKGYDIPVS-RTAKGNAIVNFL-QSD-E
K--SVLPLD--NNRKYLFFATEKGLVKKVEINAFDN-R-SGLIAIKIK--DKLIW---TD---HIQLITANGQAI------VRDMGRGAAGVFGIRLKK-
-SMVGMGIISTKYQVLTIMENGFGKRTAL-LFK-QGRGGSGIITA---TDKTGKV-SAYVLN-EKDLVVISEKGQVIRLPF-TVPL-GR---GVRLMRLK
G-KVASVTWV--
>tr|A0A0G1AIR6|A0A0G1AIR6_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWC2_42_12 GN=gyrA PE=3 SV=1
VEDLVPNEEAVVMMTRDGYIKRTTPDTFKVQGRGG-G--ILT--ED-MVDFMFTTLTHNDLLFFTTKGRVFQLKAYEIPQT-RTAKGTPIVNFL-QAG-E
K--SVLPLD---KSKYLFFATEKGLVKKVEIDAFAN-R-SGLIAIKIK--DKLIW---TD---HIQLVTAMGQAI------VRDMGRNAAGVRGIRLKK-
-QVVGMGIIKNKYQLLAISEHGFGKRSAV-LYK-QGRGGSGVKTA---TAKTGKI-NAFIVN-AKDIIIISEKGQVIRLPF-SVNQ-GR---GVRLMRFK
E-KVACVTWV--
>tr|A0A0R2S4S6|A0A0R2S4S6_9FLAO DNA gyrase subunit A (Fragment) OS=Cryomorphaceae bacterium BACL11 MAG-121128-bin16 GN=ABR81_04790 PE=4 SV=1
IEDMIPNEEVLITISHLGYVKRTSLSEYRSQNRGGVGSKGAAT-DEDFVEEMIMANNHDYMLFFTEQGKCFWLKVYEIPEGSKTSKGRAIQNLINLPKDD
KVMAYINTKK--NSHYIVMCTKQGVIKKTSLEQYSR-RTNGINAITIREGDQLLEAKMTTGKSQIMMAVKSGKSIRFE---VRAMGRTAAGVRGVRLAK-
-DVVGMICIDDQSSVLVVSEHGYGKRSDVEDYRITNRGGKGVKTINITE-KTGNLIALKNVT-LDDLMVINKSGITIRIGVDTLRVMGRATQGVKIIRLR
-ESIASVAKVS-
>tr|A0A0A7GHU1|A0A0A7GHU1_9EURY DNA gyrase subunit A OS=Geoglobus acetivorans GN=gyrA PE=3 SV=1
EADLIAEEENLLIVTKSGYAKRVDLKSFRAQGRGGVGVQGINL-NEDEIAFLGIVNSAHRLILFTNKGRAYWINAYEIPKLDRVARGTSLRNMVSMESDE
HVVSALS---F---GEILLLTADGYIKTVKLSEFENAKRSGIIAVTGEPV----AVK-PARGKEVIITTRKGMLVRFDR--VPTYGRTAKGVKAIRLK--
-DIAWMD---CEKEILLLSENGYGKRVKTGEFRKISRGGQGVICF--TK--TGNVVFAEF-VRGNGLFAFSRDGNVILVNMDEISVQGRNTTGVIVARNG
-VATQVVL----
>tr|D3S0F9|D3S0F9_FERPA DNA gyrase subunit A OS=Ferroglobus placidus (strain DSM 10642 / AEDII12DO) GN=gyrA PE=3 SV=1
EVDTIKDEENVLIITKDGYAKRLDESDFRVQRRGGVGTSG--I-DGDYAAYIVKVRSLDRILLFTKDGKAFSINAYEIPKQERSGKGVSLKRFL-RIEDE
-IVGI-----F--KGSVVILTESGYIKKVNIAEFENAKRSGILASPESVA------FKKLDGKEVIIATENGRLVRFKA--VPEYKRNARGVKAVSLD--
-IAWMD-VGSE-DLILTLTENGYGKMTKTEEFRLTGRGAKGVTAH--NE-KTGKLVFAEFV-KSDKLMVISKDGNVIVVETKQIPVMGRNAVGVAVSKKG
--ISASFI----
>tr|F2KND5|F2KND5_ARCVS DNA gyrase subunit A OS=Archaeoglobus veneficus (strain DSM 11195 / SNP6) GN=gyrA PE=3 SV=1
AEELVSFEENILIVTKNGFVKRMSI-GFKTQHRGG-G--IIG--DD-EPAIIVKCNSRDKLLVFTA-SKAYWLNAYEIPKE-RTGKGVNIRMYL-SPG-E
R--AIVPFQ--E--GDILILTEDGYIKRTPLSEFEN-K-AGIVASGGK-----IA---HK---EVFIATTNGYAV------VPEYGRSAKGVKAISLRQ-
-DIAWLSC---DGDILTLTADGHGKRTAV-EYR-VSRGAMGVIN-----ARSGGV-FSEYVE--EDLLTISKDGYALKIEV-SIPR-GR---GVIVSRKG
----AC-ATLL-
>tr|N0BMQ6|N0BMQ6_9EURY DNA gyrase subunit A OS=Archaeoglobus sulfaticallidus PM70-1 GN=gyrA PE=3 SV=1
FEDLVTQEDNIIVITSEGYVKRMDIETFRTQRRGGVGVIGVSL-QNDYPEIVSVCNTHHKLLFFT-KSKAYWINAYEIPKQDRNGKGIHLKNFISLSEGE
KVVSVVSVP---DGEV-VILTEDGYIKRTKLSEFENAKRGGVSCNSA--------FVRLLKGDIILISTKMGLTAKIPV--VPRYSRTAKGVRAINMQ--
-SIAGLT--FADGYLLTLTEKGFGKRTPVEEYRLTRRGAKGVRNI--TS-KNGHVVFAEFVKGGEELLTMSEDGYAIKISVDEIPVYSRNSAGVSVSKKG
-K----AVLI--
>tr|A0A0F7DBG2|A0A0F7DBG2_9EURY DNA gyrase subunit A OS=Geoglobus ahangari GN=gyrA PE=3 SV=1
EEDLISEEENLLVITRSGYAKRVDLKSFRAQGRGGSGVIGVNL-SDDAITFVGTVNSTHRLILFSNRGRAFWINAYEIPKMERTARGGNLRHLIGLENGE
YIVSALSVE---EGRA-LILTRDGHIKAIEVEEFVNAKRAGITAVSGE---IL--AVKPMAGKEVIISTKNGMLARFDA--VPVYGRNAKGVKAIRLK--
-EIAWMD--CG-REVLILSEGGYGKRTPLEEFRKIGRGGQGVICF--RD-KTGRVVFAEFVRE-NGIFALSSDGNAILVEIEQISVQGRNTSGVIVARSG
-E----AVQVR-
>tr|A0A094IJQ2|A0A094IJQ2_9MOLU DNA topoisomerase (ATP-hydrolyzing) OS=Mollicutes bacterium HR2 GN=gyrA PE=4 SV=1
AKNEVPSQNVVVTFTHGGLIKRVSTNKFKPQTKGG-G--K-N---N-IYSHVFIGNTQNYMLAFSNYGNVFKVLINDIKED-NRVNGAPIASLV-NDG-E
E--VVSSME----DDSLIFITKNGKVKKTKLSEYQN-K-SKIKAINLK--DSLVN---K---EDIIMYTKDGYLI------INSTGRSTGGVNGIKVKD-
-GVIGFDSIDK-KYLMTISREGKGKKIPV-MVL-QVKGGVGLNVT---QEL---A-AIIPIT-E-SITIFTNT----------ITL-TV---CAV--GVK
I-SKNVVAVIK-
>tr|A0A0G1D4Z3|A0A0G1D4Z3_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWA2_43_13 GN=gyrA PE=3 SV=1
QEDLIAKEEVVIMLTRDGYIKRVPPDTFKSQGRGG-G--ILT--ED-TVEEILTANTHSQLLFFTTKGRVFQLPAYEVPVS-RTAKGQAVVNFL-SHN-E
K--AIVSMA---KEKYFVMVTLQGVIKRVEISAFQN-R-SGLIALTLK--DRLAW---SD---DMMLVSSHGQAI------IRAMGRTAAGVRGMRLKE-
-SIVGMEIIRRPHYLLVVTEYGSGKRTNT-EYK-QKRGGSGIKTA---TKKTGTV-SARVVPDKGDLVMMSSKGQVIRLPL-SVNV-KR---GVRLMRFK
T-TIASVTLV--
>tr|B8CXA6|B8CXA6_HALOH DNA topoisomerase (ATP-hydrolyzing) OS=Halothermothrix orenii (strain H 168 / OCM 544 / DSM 9562) GN=Hore_11750 PE=4 SV=1
KTDLIKKEKVFLTFSYRQNIKRTTSSEYA---RA----------ND-YIIDTMTGTTLDTLLFFTNTGDVYTLPVHKIPEH-GLSTGDNIKDFLKI-S-K
K--KVICLN--TKEKYITIATKQGMVKKTIGGEYQT-T-SRIKAIKLN--DEVVG---TQ---EILLGTKKAKTI------VSDTGRNTIGSIGIKLA--
-GVVSFNLV-NNTSVVSISKTGRGKRSPI-EYN-QNRNGKGLKTC---SIY--KA-GVIC-A-DDYILITTGNEKLYTVKV-DLTE-SR---MYEVVSLK
D-KITGVEKLP-
>tr|E4RKI2|E4RKI2_HALHG DNA topoisomerase (ATP-hydrolyzing) OS=Halanaerobium hydrogeniformans GN=Halsa_1263 PE=4 SV=1
KQDLIKEKEAVVSLSYRGIIKRN--EEYS------------LR-ND-YLISTVKGSSLDQLLFFSDHGEVYNLQVHELEEH-GLATGDNLSKYM-QP--E
N--S-LNIL--KQNNFYVFVTESGQIKRTAAKEYET-Y-HIRA--IKL--DKLIN---E---DQIMIISQNGYAI------FSSTGRNTMGSKAIKLAK-
-NVTAFSIFN-NKYLVSVTETGRANKIKL-QFR-QKRNGRGQRIF---QNY---L-GAAFCE-NEKILIAAKNGEMYTVEV-KIPE-SP---MYQI-TKN
D-KITRVKKIL-
>tr|M5DZF6|M5DZF6_9FIRM DNA topoisomerase (ATP-hydrolyzing) OS=Halanaerobium saccharolyticum subsp. saccharolyticum DSM 6643 GN=HSACCH_01116 PE=4 SV=1
KDDLIKEKNAVLSLSYRGIIKRN--EEYK------------LR-ND-YLISTVEGSSLDQLLFFSNQGEVYNLQVHDIDEH-GLATGDNLSKYL-QP--E
N--S-LNIL--SKNEYYTFVTESGLIKRSTADEYRT-Y-HIRA--IKL--DQLIN---D---QDLFVVSKNGYII------FSTTGRNTLGSKAINLSK-
-NTIYFNTYS-DDYLISISEDGRANKIKL-NFK-QKRNGKGIRIF---TNY---L-GAVKAA-NDKLLIAAKNGEINEINV-DVPE-SP---MYKV-TQE
E-KIVAVEKII-
>tr|E3DLD3|E3DLD3_HALPG DNA topoisomerase (ATP-hydrolyzing) OS=Halanaerobium praevalens (strain ATCC 33744 / DSM 2228 / GSL) GN=Hprae_1019 PE=4 SV=1
KNDLIKEKKAIISLSYRGIIKRN--DEYK------------LR-ND-YLISTVGGSSLDQLLFFSNQGEVYNLQVHNIEEH-GLATGENLSKYL-QP--E
S--D-LNIL--TKNKYYTFVTENGLIKRTEVDEYRT-Y-HIRA--IKL--DQLVN---D---SDLIVISKKGYLI------FSTTGRNTLGSRAINLIK-
-NVLYFSTFE-NSFIISISENGRANKIKL-EFE-QKRNGKGNRIF---KSY---L-GAVKAK-GDKILIAAKNGEIYEIEV-QIPE-SP---MYQI-TKE
D-KITTVKKII-
>tr|D9QPQ3|D9QPQ3_ACEAZ DNA gyrase subunit A OS=Acetohalobium arabaticum (strain ATCC 49924 / DSM 5501 / Z-7288) GN=gyrA PE=3 SV=1
ESDLIKNEDIVLSFSYNKYLKRTTDIENI---RA----------GD-YITDIMTGTTRDDLLFFTNTGQVHILKTHKIPEH-GLSTGDPLSDYLKL-D-E
E--DILILT--TKEKYITIATEEGLIKKTVGKEYET-T-SSIKAINLN--DEVIG---TQ---NLLLGTKGGQTI------ISDTGRNTKGSKGIDLA--
-NVISFNLT-ASNYVITATADGRATRTDI-AYQ-QNRNGKGLKTL---DSY--EI-DIIT-A-EDKLLFVTEEGQLEEAPV-EITE-ER---MYTQFKLD
D-KIKEVIRLP-
>tr|A0A0G1KE27|A0A0G1KE27_9BACT DNA gyrase subunit A OS=Parcubacteria (Azambacteria) bacterium GW2011_GWA1_44_9 GN=gyrA PE=3 SV=1
LEDMIPDEESMLVYTKGGYVKRTNPSEYRKQNRGG-G--VLN--ED-FITLFMSATTHSDMLFFSDRGKAYQIKMYDIPEK-RATRGKSIMNFI-ASE-E
K--SILAMPE--GKLALFMVTKQGTIKKSSAESFKD-R-SGIISIKLD--DELLA---T---DDIILTTAKGQAI------VREMGRTAGGVRGMKLGN-
-FIIGADVVKKKPELLVMSENGYGKKTAI-EYK-QKRGGSGIKTA---TAKIGAM-TAKVVT--EELVAISKKAQVIRIDI-DVPT-GR---GVRIMKLY
G-GIASLTCL--
>tr|T0M6S0|T0M6S0_9EURY DNA gyrase subunit A OS=Thermoplasmatales archaeon A-plasma GN=gyrA PE=3 SV=1
IADLVPEEDDVIILSEGSLLKRVSLEEYRAQRRGG-G--ITS--ED-SVKTILSCSSHDSIFMFTNTGRVLRTLAYEIEKS-RKSVGVTAASYV-PQG-E
V--QIM--KR---ESHLVILTRNGFIKRTPAEAILD-R-SGIRIISLV--DEVVS---V---GNIVAISNSGKAS------VRPTGRTSRGVRAMRLK--
GEIITGFVA--DEEILTVSEKGIGKRTPI-EFS-HHRGTSGILVF---TDRTGNV-KAIPVK-DDEIMIITRNEKTIRLKV-GIKT-KR---GVKLIDTS
D-TVIEVSRIE-
>tr|Q6KZ52|Q6KZ52_PICTO DNA gyrase subunit A OS=Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828) GN=gyrA PE=3 SV=1
EEDLIPNEESVIILSEKGLLKRVSLDEYKSQRRGG-G--ITN--ND-SVKSVVSCMAHDTLYFFTNTGRVLKEKAYRIEKD-RKALGVSGNKFL-KNN-E
I--QII--KL---EDLLIIVTKNGFIKKTNISEILD-R-SGIKIINLA--DEVVS---I---SKIFVAASNGKAA------VPLTSRSSRGVKSMKLN--
GSVISAFPV--DDTILSITENGLGKRTRA-EFP-HHRGSSGVYLF---NEKTGKV-MALPVK-DDEIIIVTKNDQTIRIKS-DISI-SR---GVRLVGLT
N-SISTACVV--
>tr|A0A0Q0RN06|A0A0Q0RN06_9EURY DNA gyrase subunit A OS=Acidiplasma cupricumulans GN=AOG55_02510 PE=4 SV=1
DEDLIPNEESILILSNNGLIKRVSSEEYNTQKRGG-G--VTV--ED-SVRSILSCMSHDLLYFFTNTGRVLSAKAYTIEKS-RTAVGVSGSTFL-KLG-E
I--QIM--RK---KSFLIIVTKNGFIKKTPVREILN-R-SGVKIINLD--DEVVS---L---SKIFIVASNSKAA------VSSTGRTSRGVKSMKLN--
GAVINAFLV--DDTVLTITENGMGKRTQV-EFT-HHRGSSGNLIF---SDRTGSV-TALPVR-GDEILIITKKSKTIRISA-EIRI-SR---GVRLINLD
D-SVIAASVL--
>tr|S0ARE2|S0ARE2_FERAC DNA gyrase subunit A OS=Ferroplasma acidarmanus fer1 GN=gyrA PE=3 SV=1
DEDIIPNEESIMILSENGLLKRVSSEEYNVQKRGG-G--ITA--ED-TVRSILSCMSHDMIYFFTNTGRVLRTKAYTIEKS-RTSLGSVGGTFL-KNN-E
K--QIM--KP---KNFLIIITKKGFIKRTPVKEILD-R-SGLKIIKLD--DEVVS---L---SKIFVAASNNKAA------VSSTGRASRGVKSMRLN--
GAVINSFLV--NDTVMSITENGLGKRTKI-DFS-HHRGSSGNLIF---SERTGSV-TALPVG-SQEVLIVTRNNKTIRLNS-EIKI-SR---GVKLINVD
D-LVVAASVL--
>tr|Q97BB5|Q97BB5_THEVO DNA gyrase subunit A OS=Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1) GN=gyrA PE=3 SV=1
TEDLIPNEESVIMLSYGGLVKRVPIDEYRSQRRGG-G--NTS--SD-TVKSIIHCFSHDTIYFFTSGGRVFKIKAYEIPKS-RTSLGVSAGAFL-KQN-E
R--EVM--KR---GEHLVLVTRNGFVKKTPADPVFD-K-SGLKIITLD--DELVS---I---TNMFVLSSKGKGS------VRETGRSSMGVRSMRLG--
EDVVTAFVV--GQDILSISEKGFGKRTNL-EFP-HHRGSGGVLVY---TERTGKS-QAIPVK-DDEVIIVSMNEKTIRIKA-EIPE-SR---GVKLIDLE
G-RIMAVAVF--
>tr|Q9HJB6|Q9HJB6_THEAC DNA gyrase subunit A OS=Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165) GN=gyrA PE=
MEDLIPNEESLIMLSYGGLVKRVQADEYRSQRRGG-G--NTS--SD-SIKSMIHCFSHDTVYYFTNTGRVFKSKAYEIPKS-RTSLGVSAAAFL-KAG-E
R--EIM--KK---GYYLILVTRDGSVKKTAADPVFD-K-SGLKIITLE--DELVS---T---KNMFVLSSKGKAS------IRETGRTSMGVRSMRLN--
GDILTAFVV--DEDILSISEKGYGKRTNI-EFP-HHRGSSGVMVY---TERTGRS-HAIPVR-EDEVILVSMNEKTIRIKA-EIPE-SR---GVKLMDID
D-RVIAAAVIK-
>tr|T0N4G7|T0N4G7_9EURY DNA gyrase subunit A OS=Thermoplasmatales archaeon Gpl GN=gyrA PE=3 SV=1
EDQTIPVEESVIILTEKGFIKRVTLDEYRAQKRGG-G--QSV--ED-QVRSLIHCSSHDNVLFFTNTGRVFKIKAYRIESS-RTGVGVIGSAFL-RAS-E
R--EVLKFE--SEGAFLIMATRGGYIKKTSVEDFAN-N-AGIRAINLE--DELVS---LH---DIVVISSNGKAA------IRATGRTSRGVISMRVQG-
-EVIKAFA---GQNILTVSSRGIGKRTEE-EFT-HHRGSMGVKVM---TEKTGKV-DAIPVN--DEIIIMTRNEQTIRIRA-TIRE-SR---GVKLMDVG
D-EVIS-VGKV-
>tr|T0MW66|T0MW66_9EURY DNA gyrase subunit A OS=Thermoplasmatales archaeon E-plasma GN=gyrA PE=3 SV=1
VTDVIPLEECVLILTEKGFLKRIALEEYRAQRRGG-G--IS---ED-FPKNIMHCTSHDTVLFFTNTGRVLKRNVYEIETS-RKSVGVSLSAILNL-G-E
V--HIMRD---DETGYLIVTTRNGKIKKLKKDQLKN-R-NGLRLISLN--DEVVA---D----QLVVVSSAGKAS------VRSTGRGSMGVKAMRLK--
-KIISAFSLPEGNSLLTVSSNGIGKRTNP-EFQ-HRRGTGGVLCM---SKKTGPA-VALPVK-GEDIIIMTRNEMTIRINV-KIKL-SR---GVKLISLN
D-EVIAIGRIG-
>tr|A0A0G1MTC5|A0A0G1MTC5_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWB1_45_7 GN=gyrA PE=3 SV=1
VEDMVPQEEVVITMSDDGYIKRIPPSTFRRQRRGG-G--KSD--ED-VLAHFLGAHTHDNMLFFTDRGKVFQTKAYEIPEK-RTSKGKAIHNFL-EPD-V
K--AVITYS--ESDTYLVMATSRGVVKKVEIEKFKN-R-SGIIAINLA--DQLKW---AD---EIILSTESGRAI------VRSMGRTAGGVKGITLKK-
-NVSSFEVLGPETNLLVVMTNGYAKQTPL-EYK-QRRGGSGILTA---TDKTGKV-SSHAII-QTELLAISGRGQILKTTI-SIRK-GR---GVRIMKLD
K-ELVGTVCL--
>tr|A0A0G1QUE7|A0A0G1QUE7_9BACT DNA gyrase subunit A OS=Parcubacteria (Nomurabacteria) bacterium GW2011_GWA1_46_11 GN=gyrA PE=3 SV=1
VEDLVPKEETIITMSGDGYIKRIPPATFHSQHRGG-G--ISS--ED-ILAHFLGANTHDDILFFTDRGRVFQTKVYEIPQT-RVSKGRAVHNFL-EPE-E
R--AIINYS--DKEKSLFMATERGVVKKTTLKDFAN-R-TGIIAINLK--DALKW---AD---EVIMVTKGGKSI------TRAMGRSAAGVKGISLKG-
-GVSSFDIIKGKVEFLVVMENGYGKRTPL-QYK-QRRGGSGIITA---TNKTGGV-SSHVII-EGELLAISKKGQVIRTKI-DIRK-GR---GVRIMTLK
S-KLAGTVVL--
>tr|F8KSQ1|F8KSQ1_HELBC DNA gyrase subunit A OS=Helicobacter bizzozeronii (strain CIII-1) GN=gyrA PE=3 SV=1
VEDLIAHEDMVVTLSHRGYVKRMPLKVYEQQRRGGKGISGN-T-EDDFIEFFFSANTHDTILFVTNMGQLYWLKVYRIPEMGRSAIGKALVNLIDLQPGE
RIKATLSTA---PDKSLVFFTKKGLIKRTNLSAFGRTR-GGVRAIVLDEDDAFVTAQ----TQELFMASSKGMCIRFG---VREIGRVARGVIGMRLR--
-DVIGGGVISSQEKLLSVSSKGLGKQTLAGAYRLQGRGGMGVIAMKIT--KTGDLIGIVS-D-SQDLMILTKSGKMIRMPMESIRETGRNASGVKLVSVE
--VVVYANTCP-
>tr|A0A0N6W8N3|A0A0N6W8N3_9HELI Gyrase A OS=Helicobacter baculiformis GN=gyrA PE=4 SV=1
IEDLIPHEDMVVTISHKGYVKRVPLKVYEQQRRGGKGMSGN-T-EDDFIESFFIANTHDIILFITNTGQLYWLKVYKIPEMGRNAIGRALVNLIDLQPGE
SIKATIPTK---TDKSLVFFTQKGMVKRTELSAFGRIR-GGVRAIVLEEDDTLVTAK----VQELFMASSKGMCIRFS---VREMGRAARGVIGMRLR--
-DVIGGGVILSEQKLLSVSSKGIGKQTLAGAYRPQGRGGLGLIGVKIT--KTGHLVGIVS-D-GQDLMLLTKSGKMIRMPMDTIRETGRNASGVKLVQVQ
--EVVYASTCP-
>tr|J8JT98|J8JT98_BACCE DNA topoisomerase 4 subunit A OS=Bacillus cereus VD107 GN=parC PE=3 SV=1
VEVMIPQEDVIVTVTKEGYVKRTGWRSHNASN--G---------GD-ILLER-FDNTTETVLLFTNKGNYIYLPVYEMPE-----LGQHVANLVSL-EDE
M--WATVVP---EKRFIVFVTRNGMIKKTELNQYK----RAFVAVNLK-DEV-V----F--TSDIVLATHGAYAL------V--VGVRAAGVKAINLK--
-DVASGKPLNG-DQLILITQRGAVKRIKAS------RAKRGLVIF----KLPYRV-GIEIVR---LVYMKTEKHIVEEIDP-AFRN---YSNGSLVLDVN
T--VVETWTKK-
>tr|B9DXT3|B9DXT3_CLOK1 DNA gyrase subunit A OS=Clostridium kluyveri (strain NBRC 12016) GN=gyrA PE=3 SV=1
IEDLIEEEEVVITLTHAGYIKRISADTYSSQRRGGKGIQAMTT-EDDFVEHIFITSTHSHILFFTNKGKVYKLKGYEIPDG-RTAKGTNLVNLLPLDG-E
QIQAVISFK---DDNYFIMATKRGLVKKTEINQYAS-RKNGLNAINLRDGDELIGVK-TTG-SEVLIFTKNGYAIRFSE--VRPTGRNTTGVKAITLR--
-KAVAMDIASN-EDILVVSENGFGKRTPVTEYTIHKRGGKGIITYKST-E-TGLIVGARVVKE-DEMMLINSSNVAIRLNVSDISTTSRNAMGVTLMRTE
EQ-VVAIAKIN-
>tr|R6R9U9|R6R9U9_9FIRM DNA gyrase subunit A OS=Firmicutes bacterium CAG:449 GN=gyrA PE=3 SV=1
DEDLIPQQEIVISLTESGYIKRLTTDTFKVQNRGGVGITGTKM-KEDVISIIVYAQTHTDILFFSNLGKVYRLRGYQIPES-RTSKGLPVQNLLQLEDNE
KILSIITVDK--DDNYLFFATKDGVVKRTSVKEFELIRQNGKKAITMREEDELINVKLTDGNALISLSADNGKMVKFP---VRVMGRTATGVKGMDID--
-HVISLTTS--GKYILALSEKGYGKMSLLEEYRQTSRGTKGVITMNMTD-KTGKLVATRAVN-DEDIIVITKLGVVIRTSLKQVAI-GRNTQGVKIIRLK
-DSVSSVTSLK-
>tr|A0A0F2SJW6|A0A0F2SJW6_9FIRM DNA topoisomerase (ATP-hydrolyzing) OS=Peptococcaceae bacterium BRH_c23 GN=VR66_02445 PE=4 SV=1
SSFDEPDNLIEVMLTKNGYIKRTTLQVK--------N-KLCV--GD-SLAEKITCSEKDTLYFFSQTGKFYSINAKTVPDG-YKDKGGPLTNLFPL-G-E
K--STLSIK---DGVHLVFVTKDGQVMRSPASDFVN-R-P--EAIGLK--DSVVK---SR---DLFLATHKGQAI------INPMGRKSRGVKGIALG--
-EIVDALLLSDLRDLITITERGFLKRTSF-EFK-QGRAGKGITIS---DPVTGFV-GIAQVK-DDSLNIIQVSGTVTKIAV-NVKV-PR---GTQWIPVI
D-FAVSII----
>tr|I4D686|I4D686_DESAJ DNA topoisomerase (ATP-hydrolyzing) OS=Desulfosporosinus acidiphilus (strain DSM 22704 / JCM 16185 / SJ4) GN=Desaci_2357 PE=4 S
SSFEEVEHPFEVILTKQGYIKRIPLPSK--------I-KPLS--GD-VVSLKVSATDQETLYFFTQTGNFYCIKAKTVPEG-PKEKGSPLSNLLQL-E-E
T--AILSVK---DQSYFIFITQEGQVMRSPVKDFVH-R-A--EGMGLK--DVLTR---GG---ELFIATYYGQAI------INPMGRKARGMKGITLN--
-GVVDALLLM-LGDLVTLTERGYIKRTSF-EFK-QSRAGKGIAIT---SAKIGYT-DITRAN-EDSLEILQVEGDVTKIEI-SLKV-SR---GSQWIPVL
N-FALGMF----
>tr|A0A099SBQ4|A0A099SBQ4_9FIRM DNA topoisomerase (ATP-hydrolyzing) OS=Desulfosporosinus sp. HMP52 GN=DP73_08555 PE=4 SV=1
SSFGEPECIFQVALTANGFIKRLPVQSK--------K-KLCS--GD-TLQERIICSNKDRLFFFTQSGEFFSINSKTVPER-NKDKGGPLTNLFSL-G-E
S--STLAVK---EDLFFVFVTKSGQVMRSLVSDFIN-R-S--EAIGLK--DSVVK---SG---ELLLATRKGQVI------VNPMGRKSRGVKGITLG--
-EVVDALMGSNLSDLLTITQQGFLKRTAL-EYK-QGRAGKGIAIG---DSVTGYV-GVMQVR-DDVINVIQVSGIVTKVEI-DVKV-SR---GIQLIPVL
N-YTIKLI----
>tr|J7IYC5|J7IYC5_DESMD DNA topoisomerase (ATP-hydrolyzing) OS=Desulfosporosinus meridiei (strain ATCC BAA-275 / DSM 13257 / NCIMB 13706 / S10) GN=Desm
SAFGEPECIFQVALTANGFIKRLPLQAK--------K-KLCS--GD-TLQEKLICSNKDRLFFFTRSGEFYSINSKTIPEK-NRDKGGPLTNLFTL-G-E
S--SILAVN---EDHFFVFVTKSGQVMRSPVSDFIN-R-S--EAIGLK--DSVVK---SG---ELLLATSRGQVI------VNPMGRKSRGVKGMTIG--
-EIVDALMCVNLSDLLTITQRGFLKRTAL-EYK-QGRAGKGIAIG---DSTTGYV-GVMLVR-EDVVNVIQDSGIVTKVEM-DVKI-SR---GIQLIPVL
D-YTIKLI----
>tr|G7WB21|G7WB21_DESOD DNA topoisomerase (ATP-hydrolyzing) OS=Desulfosporosinus orientis (strain ATCC 19365 / DSM 765 / NCIMB 8382 / VKM B-1628) GN=De
SSLEEPESPIQVLLTAQGFIKRTDLPTR--------R-KLCS--GD-TLDLRLNCSNRDTLYFFSRSGKFYTIKAKTVLEK-NKDKGGPLTNLFPL-E-D
K--SILPLR---EDLCFVFVTKEGQVMRSPVSDFAH-R-S--EAMGLK--DTVVK---SG---ELFLAAQNGQGI------INPMGRKSRGVKGMTLG--
-GIADALLIAKSRDLVMVTQRGFLKRTSL-DYR-QGRAGKGIAMG---DLGTGYV-GIAAVQ-DDSLNIIQENGTATKVEI-DVKT-LR---GSQWVPVL
N-YVVRIV----
>tr|A0A0F2JCQ1|A0A0F2JCQ1_9FIRM DNA topoisomerase (ATP-hydrolyzing) OS=Desulfosporosinus sp. I2 GN=UF75_3613 PE=4 SV=1
SSFAEPESLNEIMLTKNGYIKRTALPTK--------N-KLYV--GD-YLVEKITCSERDTLYFFTTTGKFYSINAKTVPDG-YKDKGGPLTNLFPL-G-D
K--STLSIK---EGVYLVFVTKDGQVMRCQASDFVN-R-P--EAIGLK--DRVVK---SN---ELFLATYKGQSI------INPMGRKSRGVKGIALG--
-EVVDGLLLPSLRALITVTERGFLKRTSF-EYK-QGRSGKGIAIG---DPITGFI-GIAQVQ-DDLLNIIQVSGTVTKIDV-NVKL-PR---GTQWIPVI
N-FAETII----
>tr|H5XUP8|H5XUP8_9FIRM DNA topoisomerase (ATP-hydrolyzing) OS=Desulfosporosinus youngiae DSM 17734 GN=DesyoDRAFT_2113 PE=4 SV=1
SSFEEPESLYQVMITANGFIKRISGQTK--------K-KPCA--GD-TLKERINCTNKDTLYFFTQSGDFYTINAKTVPEK-NKDKGGPLTNLFTL-E-E
K--STLPVK---EELFFVFVTKDGQVMRSPVSDFAN-R-S--EAMGLK--DVIVK---SG---ELFLATYKGQSI------INPMGRKSHGVKGMTLG--
-NIVDALMLSGPGDLVTVTERGFIKRTSF-EYK-QGRAGKGIAIS---DSGTGYV-GVSHVQ-DDILNIIQLSGTVTKLEM-KVKA-PR---GKQWVPVL
N-YPVGIV----
>tr|G2FS96|G2FS96_9FIRM DNA topoisomerase (ATP-hydrolyzing) OS=Desulfosporosinus sp. OT GN=DOT_2572 PE=4 SV=1
SSFEEPESLIEVMLTSNGFIKRMPIQTK--------N-KLCA--GD-TLAEKISCTDKDTLYFFTHTGKFYSIKAKNVPEG-VKDKGGPLTNLLTL-E-E
K--SILALK---DTSFFLIVTKNGLVMRSPASDFVN-R-S--ETMGLK--DAVVK---SR---EVFLVTHQGQAI------INPMGRKSRGVKGIALG--
-EVVDALLLTSYGDLVTVTERGFVKRTPL-EYK-QGRAGKGIAIA---DPGTGYM-GIYHVK-ENVLNIIQVSGNVTQIEM-NVKR-SR---GKQLVPVL
N-YVVRII----
>tr|A0A0A2TH42|A0A0A2TH42_9FIRM DNA topoisomerase (ATP-hydrolyzing) OS=Desulfosporosinus sp. Tol-M GN=JT05_13465 PE=4 SV=1
SSFAEPESLIEVMLTTKGFIKRMPFQTR--------N-KLCA--GD-TLAERITCTDKDTLYFFTHTGKFYCIKAKTVPEG-NKDKGGLLTNLCPL-G-E
K--STIPIK---DAIFFVFVTKDGQVMRSAVSNFAD-R-S--ETMGLK--DAVVK---SG---ELFLVTRQGQAI------INPMGRKARGVKGMTLG--
-EIVDALLLTSLGDLVTLTERGFVKRTSF-KYK-QGRAGKGIAIG---DPGTGFV-GVARGT-DDLFYVIQGSGAVTQIEM-NIKA-SR---GAQWVPVL
N-YTVRII----
>tr|U3XR81|U3XR81_PEPDI DNA gyrase subunit A OS=Peptoclostridium difficile E15 GN=gyrA PE=3 SV=1
MRDLISDEEIAITLTHFGYIKRLPSDTYKSQKRGGRGISALTT-EEDFVRHLVTTTTHSRLLFFTNKGRVFKLNAYEIPEGKRQAKGTAIVNLLQLSA-E
KIATLIPID---ENEYLLLATKKGIVKKTKREEFKN-NKSGLIAIGLRDDDELIGVE-TDG-QEVLLVTKEGMSIRFDE--IRYMGRTAMGVKGITLS--
-EVVSMNLCSKGTDVLVVSKNGFGKRTNIEEYRSQIRAGKGIKTYNIS-E-TGTIVGADMVND-DEIMIINSDGVLIRIRVNEISLFGRVTSGVKLMKTN
E-NVVSIAKIN-
>tr|A0A073JX84|A0A073JX84_9BACI DNA topoisomerase 4 subunit A OS=Bacillus manliponensis GN=parC PE=3 SV=1
VEVMIPQEDVVVTVTKEGYVKRTSWRSHNASN--G---------SD-MLLEK-FENTTETVLLFTNKGNYIYLPVYELPD-----LGQHVANIVSL-EDE
T--FATVVP---EKRFIMFITRNGMIKKTELSQYK----RAFVAVNVK-DEV-V----F--TKDILLATHGAYAL------V--VGIRAAGVKGINLK--
-DVTCGRAIDS-DLLTLVTQRGAVKRLKAS------RAKRGLVVF----KLPYRV-GIEVVR---LVYMKTAKQMIEVIDP-TLRN---YSNGSLVLDVS
A--VVETWTEK-
>tr|I4A978|I4A978_DESDJ DNA topoisomerase (ATP-hydrolyzing) OS=Desulfitobacterium dehalogenans (strain ATCC 51507 / DSM 9161 / JW/IU-DC1) GN=Desde_2167
SAFEEPEKPMEVLLTKKGFIKQMPTPTR--------S-QVFA--GD-VISEQLSCTSKDTLFFFTHNGKYYDAKAKLVPEG-AKDKGRAVNNLFPL-E-E
R--AMLSLR---EGQHFVFVTRDGQVMRSPVKDFLN-R-P--EAMGLK--DEIIK---SG---DLFLASFQGQAI------VNPMGRKSRGVKGMTLN--
-EVVDALLIQPEGDLITVTEQGYVKRTSF-EYK-QGRAGRGIAIA---DAKTGYV-SLIPIG-DKILHIIQAGGTVTHVEA-SLKR-SR---GAGLVNVI
N-YIVHVV----
>tr|A0A0J1FGT2|A0A0J1FGT2_9FIRM DNA topoisomerase (ATP-hydrolyzing) OS=Peptococcaceae bacterium CEB3 GN=gyrA_1 PE=4 SV=1
TVLAEPAEPLEVLLTGKGFIKARIPGKNGHGKRRD-A-VDFQ--ED-ILRHKVCCTDQDQLLFFSASGRVYSLAAKLVPEA-GRAKGKALSALVPL-G-E
E--ACRPLR----GDHVVFVTRLGQVMRSPAADFVN-R-A--EGMTLK--DTLVT---SQ---DLVLLTAQGQAL------VRAMGRKSKGVRGISLA--
-AVAAALPVT-AADLITVSERGWLKRTPI-EFK-QKPGGKGVTAA---DLKTGLA-TALLAD-GSALTALQRSGAQTRISV-SLKV-AR---GALLVAVV
D-YVIGVFA---
>tr|A0A0J1FP11|A0A0J1FP11_9FIRM DNA topoisomerase (ATP-hydrolyzing) OS=Desulfosporosinus acididurans GN=gyrA_2 PE=4 SV=1
SSFEEAEHPIEVMLTQQGYIKRIPLPVK--------L-KPLS--GD-SVAIKVQATDQETLYFFTQLGNFYSIKAKTVAEG-FKEKGSPLNNLLQL-Q-E
T--SIAALK--SGQSYFVFITQEGQVMRSPVKDFVH-R-S--EGMGLK--DRLIK---GG---ELFLATYNGQGI------INPMGRKARGIKGITLN--
-GVVDALLLVSLGDLVTLTERGFVKRTSF-EFK-QGRTGKGIGIT---NPKTGFV-GITQAK-DDVLEILQVNGEITKLDL-NLKT-PR---GIQWIPVL
D-LSVRMF----
>tr|L0F9D9|L0F9D9_DESDL DNA topoisomerase (ATP-hydrolyzing) OS=Desulfitobacterium dichloroeliminans (strain LMG P-21439 / DCA1) GN=Desdi_1831 PE=4 SV=1
STFEEPEKAMEVYLTRKGFVKQMPAPTR--------S-QLFA--GD-VIIAQAPCTSKDTLYFFTQNGKFYDAKAKLIPEG-AKEKGRAVTNFFPL-D-E
Q--ALISLK---EGQHFVFVTKDGQVMRSPVTDFLN-R-P--DAMGLK--DEIVK---SG---DLFLASYQGQAI------VNPMGRKSRGVKGMTLN--
-GVVDALMLQASGDLITVTDQGYIKRTTL-EYK-QGRSGRGIAIA---DAKTGYV-SVLQVN-TKVLHIIQESGTVTNIDP-SLKN-SR---GVGLVNVI
N-YVVHVI----
>tr|B8FW91|B8FW91_DESHD DNA topoisomerase (ATP-hydrolyzing) OS=Desulfitobacterium hafniense (strain DCB-2 / DSM 10664) GN=Dhaf_2677 PE=4 SV=1
SAFEEPEKPMEVLLTRKGFIKQIPTPTR--------S-QIFA--GD-VLLEHVSCTSKDTLYFFTHSGKYYDAKAKLVAEG-AKEKGRAVNNLFPL-E-E
R--AMVSLR---EGQYFVFVTKDGQVMRSPVKDFLN-R-A--EAMGLK--DEIVK---SG---ELFLASLQGQAI------VNPMGRKSRGVKGMTLN--
-GVVDALLIQPTGDLITVTEQGYVKRTSL-EYK-QGRAGRGIAIA---DAKTGYV-SLIQVG-DKLLHIIQAGGAVTGVEA-SLKR-SR---GAGLVNVI
N-YIVHVL----
>tr|A0A0G2ZCK3|A0A0G2ZCK3_9BACT DNA gyrase subunit A OS=Kosmotoga pacifica GN=gyrA PE=3 SV=1
VEDVIPDDDIVVAVTHKGYIKSTPLESYRKQGRGG-G--RIK--ED-FVTNILTTTRLSKTVIITSKGKAYIINNHELDYS-RDSKGKLLANYI-KDD-E
T--AILTAR---EGKYLIITTRKGKIKRTPFEAFAN-R-SGIKAITLN--DKVVS---SD---TVLISTALGMVI------IRPMGRSAAGVIGIRLRR-
-DVVSSSVVAAQRYLFTATEWGVGKRTPL-EYR-QNRGGMGLKNL---IDRIGRI-DALVVT--DELIVITKAGMSIRLPV-QIRP-GR---GVKLVELK
--SVASMAVIA-
>tr|I2F2V7|I2F2V7_9BACT DNA gyrase subunit A OS=Mesotoga prima MesG1.Ag.4.2 GN=gyrA PE=3 SV=1
IEDVIPDEDIVLMVTKKGYIKSTPLESYRKQGRGG-G--IVR--ED-FVVNILTTTRLSKTVIITSKGKAYVLSNHIIDHS-RDSKGKLLANYI-KDD-E
N--AVLSTR--VQGKQLVITTRSGKIKKTEFEAFLN-R-SGIKAISLN--DRVID---TD--DTIIISTKNGMVI------VRSMGRSAAGVMGIRLKK-
-DVVGANIVA-TRFLLTATEKGGGKRTCL-EYR-QNRGGLGVKNI---LEKIGKI-GTLVVN--DEVILATKLGMSIRIPV-QVRP-GR---GVRIVDLK
N-IAASMAVVV-
>tr|A0A095ZQ50|A0A095ZQ50_9FIRM DNA gyrase subunit A OS=Peptoniphilus lacrimalis DNF00528 GN=gyrA PE=3 SV=1
IEDIIKEEDVIITLTQMGYIKRMPEGTYKPQKRGGRGITALTQ-EDDFVKELFVTSTHDRLLFFTNKGKVYRLKAFEVPEG-RNAKGTAVVNLLNLDKGE
KITSVINVE---PNYYLLMVTEKGLIKKTSNKEFKN-RQNGLIGIKLRDDDKLISVH-VRG-EEIILVTKEGKSIRFST--LRDQGRNTMGVKSMNLD--
-DIVSSDIVG--NYLLTVSENGFGKLTELKEYRPQNRGGKGIFTYKIS-E-TGKVSAASVVNS-DDIMLIADSGIIIRLLIDDISVTSRNTMGVKLM--N
NDKVVAIAKYI-
>tr|A0A095XLR4|A0A095XLR4_9FIRM DNA gyrase subunit A OS=Tissierellia bacterium S5-A11 GN=gyrA PE=3 SV=1
DADLIEEEDVVITMTNFGYIKRMPEGTYKPQRRGGQGISALTR-DEDFVSNLYITSTHDTILFFTNKGRVYSLKAYQVPQ-GRTAKGTAVVNLINLQKDE
TIQEMMPVK-FE-EDSLVFVTKDGLIKKTLISEYSNIRSNGLNAIQLNEGDELVTVRQSCPGDEYIVVTKEGMAIRFT---VRNIGRNGQGVKAISLD--
-QIVSMDIVK-DNYLLAITENGFGKMTELNKYKVQRRGGKGLITYKINK-KTGPLVSGKVVD-KDEIMMISQSGTIIRLETKDISV-GRSTSGVKLMNIK
S-NVVSVAKYL-
>tr|B0S421|B0S421_FINM2 DNA gyrase subunit A OS=Finegoldia magna (strain ATCC 29328) GN=gyrA PE=3 SV=1
DMELLEEEDMFITITNKGYIKRISTDAYKVQHRGGRGVNAMGM-DGDFIKDMFATTTHQDLLFFTNKGKVYSLKAYEVPE-SRTARGSNIINLIQIDADE
NVTQVLALD-EENDQFIIFITKKGKVKKTSLSLYENIRKTGIIAIKFDEGDELIDVKLVEKNEEVIIVTKKGMSLQFN---LRDLSRNAIGVKAITLN--
-EVISFDLVK-NEFLAVISENGYGKKTELSNYTTQNRGGKGIRTYKIAK-KTGDVACAKALK-DDEILLISKQAEVIRIKAEGIST-SRNTSGVLLKNTD
GEAIVAVAKYF-
>tr|A0A090HVW0|A0A090HVW0_9FIRM DNA gyrase subunit A OS=Peptoniphilus sp. 1-1 GN=gyrA PE=3 SV=1
IEDIIKEEDVVITLTKLGYIKRMPEGTYKPQRRGGRGISALST-DGDFVCDLFVTSSHDSILFFTNLGRVYRLKSYEIPES-RQARGMAVVNLLELSA-E
TIQSIIPVK---PDLNILMATKKGIVKKTSFEEYKN-RKTGIISMNLKEEDSIIATM-TTG-EDVIIATKKGKAIRFSE--VRNTARNSMGVKAIELD--
-DVIGCEIADD-KFMLVISERGYGKITPMTEYRTQSRAGKGMITYRPK-Q-TGNLVSSKVVDE-DEIMIITVEGIIIRIKVDEISTMGRATSGVKLMNIT
SE--VAVATYI-
>tr|D7N8B2|D7N8B2_9FIRM DNA gyrase subunit A OS=Peptoniphilus sp. oral taxon 386 str. F0131 GN=gyrA PE=3 SV=1
LEDIIKEEDVVITLTQFGYIKRMPEGTYKPQKRGGRGISALTT-EEDFVNDLFITSTHDLILFFTNLGRAYVLKAYEIPES-RQSKGTAIINILNLSANE
KVQSIIPVR---PNLNIVMATKDGIIKRISFEEIKN-RKSGINAMTLRDGDSIIGTR-TTG-DELILVTKKGMSIRFKE--VRLTGRTSMGVKAIELN--
-DVVGFDVVS--KYLLVISQNGFGKLTPIDEYRIQSRAGKGIITYKVK-D-TGDLVSAKIIDN-DEIMMITSEGIIIRIETEGISVMGRSTSGVKLM--N
KDEVVAVAKYI-
>tr|F5TDR7|F5TDR7_9FIRM DNA gyrase subunit A OS=Parvimonas sp. oral taxon 110 str. F0139 GN=gyrA PE=3 SV=1
IEELIKEEDVVITLTKQGYIKRIPSDTYKVQNRGGKGVVALTI-EDDYVDSLFVTSTHSLILFFTNKGRVYKLKAYEIPEK-RQAKGQNIINLLELMHGE
KVNAVIPVK---ADEYLIMATKKGTIKRTSVELFKS-RKVGMKAINLVDDDELIQVR-SPV-DSAILVTKKGLAIKFAL--LREIGRTGQGVRGIKLD--
-DVVSMNLDS--KHLLVFSEYGYGKRTLASNYKVQNRGGKGVKTYKVT-E-TGFVVSSKMVNN-DEVIVLSQSGGIIRLLVKDIPVKGRDTQGVIIKDVN
DEKIVAVAKYV-
>tr|U7UNP3|U7UNP3_9FIRM DNA gyrase subunit A OS=Peptoniphilus sp. BV3C26 GN=gyrA PE=3 SV=1
EEELIAEEDVVITLTQFGYIKRMPEGTYKPQRRGGTGIAALTT-EEDFVKDLYITSTHDTILFFTNFGRVYSLKAYDIPE-SRQAKGTAIVNLLNLSRDE
QVTAVVPVR-EE-SSSLTMITKNGLVKKTGYSEFKNIRKNGLNAINLREGDSLIAVRLTKKNDEIILVTKNGMSIRFG---VRSMGRSAQGVKSIELK--
-EVVSFDIAE-EKYLLVISQGGYGKMTKMSEYRNQNRGGIGLITYKITE-KTGKVISAKVID-SDEVMMITEKGIVIRIQTEGISV-GRHTSGVKLMNLK
S-EVVAVAKYV-
>tr|E4KWZ1|E4KWZ1_9FIRM DNA gyrase subunit A OS=Peptoniphilus harei ACS-146-V-Sch2b GN=gyrA PE=3 SV=1
IEDIIKKEDVVITLTQFGYIKRMSEGTYKPQKRGGRGVSSGNM-DKDFVKELFVTSTHDMILFFTSLGNVFKLKAYEIPE-SRTSRGTAIINLLDLDEDE
RVTSIIPVK-YP-DLNFLMVTEKGLIKRTPFKDYKNIRKSGIIAIKLNEGDKLIDVHLTKDDEDVILVTKKGLSIRFN---VRKSGRNSMGVKSMDLD--
-IVVSSDLVV-DKYLLVISENGYGKLTEIDKYRPQNRGGKGLLTYKITN-KTGDVASAAVVE-EDDVMIIANSGIIIRILTEDISV-GRNTSGVKLMNLT
A-KVVAVANYI-
>tr|A0A0C7PFB3|A0A0C7PFB3_CLOSO DNA gyrase subunit A OS=Clostridium sordellii GN=gyrA PE=3 SV=1
MRDLIENEEVAVTLTHFGYIKRMPIDTYKSQNRGGRGISALTT-EEDFIKELITTQTHSRLLFFTNKGRVYRLNAYEIPEAKRQAKGSAIVNLLQLNS-E
KIATMISID---DSQYLLLATKNGIVKKTKREEFKN-NKSGLIAIGLREDDELIDVR-TDG-EDVILVTKGGMSIRFDE--IRHMGRTAMGVKGITLN--
-NVVSMNLCSEGTDLLVVSENGFGKRTSIEEYRSQIRAGKGIKTYNIA-D-TGDIVGAQMVND-DEMMIINSDGVLIRLRVNEISLFGRVTSGVKLMKTN
E-NIVSIAKIE-
>tr|A0A0B3VVK8|A0A0B3VVK8_9FIRM DNA gyrase subunit A OS=Terrisporobacter othiniensis GN=gyrA PE=3 SV=1
MRDLIDDEEIAITLTHFGYIKRVPLDTYKSQNRGGKGITAMST-EEDFVKHLVTTTTHSRLLFFTNKGRVFRMDAFEIPEGKRKAKGTAIVNLLQLAP-E
KITTLIPVD---EELYLLLATKKGIVKKTKREEFKN-NKSGLIAIGLRSDDELIDVK-TNG-KDVLLVTENGMSIRFNE--IRPMGRTAMGVKGITLS--
-DVVSMNLTDEGHELLVVSEKGFGKRTDINEYRVQSRAGKGIKTYNIF-E-TGKIVGAEMVDK-DQMMLINSDGILIRLQVEGISIYGRVTSGVKLMKTE
E-NVVSIAKIN-
>tr|F4A316|F4A316_MAHA5 DNA gyrase subunit A OS=Mahella australiensis (strain DSM 15567 / CIP 107919 / 50-1 BON) GN=gyrA PE=3 SV=1
IEDLIQDEEVAITLTHFGYIKRLPLDTYKSQRRGGKGITGMQT-DEDFVEHIFVTSTHSYMLFFTNKGKVYMMRAYDVPEG-RQAKGTAIINLLNLSG-E
KISAVIPIR---DEKYLIMTTREGYIKKTSIEEYDN-HKNGLMAIGLGEGDELIGVE-TNG-NEVIISTKEGMAIRFPE--VRSMGRTARGVKAIKLN--
-GVIDMELVDE-ADLLMVSENGYGKRTPLKEYRSQSRGGKGIITMKIT-E-TGPLAAIKVVHD-DEIMMVTSDGIIIRLEVKGIPVQGRNTQGVTLMKVE
GQ-IVSLAKFE-
>tr|G2IFJ0|G2IFJ0_9CLOT DNA gyrase subunit A OS=Candidatus Arthromitus sp. SFB-rat-Yit GN=gyrA PE=3 SV=1
RDNLIHKENIVVTLTHDGYIKRMASNTYSSQKRGGRGMQAMTV-ENDFIENIFHTTTHHNLLFFTNLGRVYNIKAYEIPD-SRIAKGINIVNLINLNSNE
KVQVVLCLD-LD-NGYVLMATKLGLIKKTKISEFSKIRKNGLIAIGIKDNDELLNVKQTKGDADIVMVTSCGYAIVFN---IRAMGRGASGVKAITLR--
-SLISIDIAT-GEDLLITSENGYGKRTALKNYPVQNRGGKGIKTYKITE-KTGKVSCACVVN-NNDVMLINSNGVGIRIKVSDISQ-GRSSLGVKLMRTT
NEKITTIGKIK-
>tr|A0A098EKM4|A0A098EKM4_9BACL DNA topoisomerase 4 subunit A OS=Planomicrobium sp. ES2 GN=parC PE=3 SV=1
REVMIPSEEVVVTVTKEGYVKRTSTRSHAASN--G---------TD-HLLFE-GNNTQNTILLFTTAGNFVYQPVNELPD-----LGQHLSSIVQL-ENE
S--AAYPFE----DAYILTVSKNGLVKRSALKDYH----RAIKTMNLK-DAM-I----G--ETELFIGTNQAYGV------I--TGLRTAGVKGVNLK--
-DVVSAILINPQ-DLILVTHRGAAKKMKLQ------RAKRGVVML----RLPHRV-AVIAAA---EVLLETAKGIRTNLAA-NLKT---YSNGSFILDEG
D--VIVAYRIE-
>tr|A0A0B4RBM9|A0A0B4RBM9_9BACL DNA topoisomerase 4 subunit A OS=Planococcus sp. PAMC 21323 GN=parC PE=3 SV=1
REIMIPSEEVVVTVTKEGYVKRTSTRSYAASN--G---------TD-HLLFE-GNNTQHTILIFTTAGNFVFQPINELPD-----LGQHLSSIIQL-DNE
S--AVYPFE----DASILTVSKLGQVKRSALKDYQ----RTVKTMKLK-DAM-I----G--ETELFIGTKQAYGV------V--TGLRTGGVKGVNLK--
-DAVSAILINPQ-ELVLITHRGAAKKMKLD------RAKRGVVML----RLPHRV-SVIGAT---EMILETAKGVHIPLIA-SLKN---YSNGSFIADES
D--VVEAYLLN-
>tr|I4X0D0|I4X0D0_9BACL DNA topoisomerase 4 subunit A OS=Planococcus antarcticus DSM 14505 GN=parC PE=3 SV=1
REIMIPSEEVVVTITKEGYVKRTSTRSHAASN--G---------SD-YLLFE-GNNTQHTILIFTTAGNFVFQPINELPD-----LGQHLSSIVQL-DNE
S--AVYPFE----DASILTVSKLGQVKRSALKDYQ----RAIKTMNLK-DAM-I----T--ETELFIGTKQAYGV------V--TGLRTGGVKGVNLK--
-DAVSAVMIDPQ-ELVLITHRGAAKKMKLQ------RAKRGVVML----RLPHRV-AVIGAT---EIILETAKGIRISLVA-SLKN---YSNGSFIADEA
D--VNSAYRFE-
>tr|W3AB22|W3AB22_9BACL DNA topoisomerase 4 subunit A OS=Planomicrobium glaciei CHR43 GN=parC PE=3 SV=1
REVMIPSEDVIVTVTKEGYVKRTSPRSHAASN--G---------SD-HLLYE-GNNTQNTILLFTSNGNFVYQPVNELPD-----LGQHLSSIVQL-ENE
S--SVYPFE----DASILTVSKQGMVKRSALQDYH----RTIKTMNLK-DSM-I----G--ETELFIATNQAYGV------V--TGLRTAGVKGVNLK--
-DAVSAIMLDAQ-ELVLVTNRGAAKKMKLQ------RAKRGVVML----RLPHRV-AVVGTS---EILIETAKGVRLTLAV-NLKP---YSNGSFVLDEG
D--PVTVYRLE-
>tr|A0A0D3V747|A0A0D3V747_9BACL DNA topoisomerase (ATP-hydrolyzing) OS=Paenibacillus sp. IHBB 10380 GN=UB51_05990 PE=4 SV=1
LEVMVNSEDVLVTLSKDGYIKRTSMQSFTRSG--GE--------GD-YIKRV-FENTLEKLLVFTQKGQYFLLPVHQIPE-----AGTAIVNVIHL-SED
V--GVIPIS---SDKSLVFVTRKGQVKRTELKEYM----NAVAACKVS-DEV-L----T--SKDILLISKEGMSI------V--MGRVSGGVRGIQLR--
-DIVSSLW-VKEGEILTLSDIGYGKRSLLV------RGGKGVVTF--KGKVGSRV-GAFYCK---QIVAVSVVGNMYTFSS-QSPI---KSVGKQLIQLD
N--VSDLFIM--
>tr|E6SKE5|E6SKE5_THEM7 DNA gyrase subunit A OS=Thermaerobacter marianensis (strain ATCC 700841 / DSM 12885 / JCM 10246 / 7p75a) GN=gyrA PE=3 SV=1
VEDLIAEEDVVITLTHRGYIKRMPVNTYRSQRRGGRGVTGIQT-EEDFVAQLFIATTHENLLFFTNRGKVYHRRVHEIPEG-RTARGTAVVNLIEIER-E
QVTAVIPVR---EDRDLLMCTRRGVVKRTALAEFSH-RRGGLIALALDPGDELVAVE-TDG-GDVLVVTRLGQAIRFPV--VRTMGRAARGVMGIRLD--
-GVVGMEVADD-AHLLVITDLGFGKRTPVREFRAQGRGGKGIRAISLT-A-NGRVAGFEVVRG-EEVMLISQGGIVLRVPVDQVSVQGRAAQGVTVMRLE
GD-VSAVATVA-
>tr|D9RYX7|D9RYX7_THEOJ DNA gyrase subunit A OS=Thermosediminibacter oceani (strain ATCC BAA-1034 / DSM 16646 / JW/IW-1228P) GN=gyrA PE=3 SV=1
EQDLIPEEDVVITMTYMGYVKRMPLSSYRSQKRGGKGVTGITT-EEDFVERILVATTHHVVLFFTNQGNVYRLKAHEIPEG-RTAKGTAIVNLLPLKP-E
KVNAVIPIK---EASYLVMVTKRGLVKKTLLSEYES-RKTGIIAITLTSGDELIGVK-VGK-DELILGTSHGMSIRFSV--VTPTGRTARGVKAITLG--
-GVASMDVTS--SDVLVITEKGFGKRTPLDEYRIQTRGGRGIITQRVT-D-TGRLVGLRVVAG-DDIILCTASGMMIRLEVSGISSMSRNTRGVTLMKLE
GD-VSAVAVIR-
>tr|W7DA96|W7DA96_9LIST DNA topoisomerase 4 subunit A OS=Brochothrix campestris FSL F6-1037 GN=parC PE=3 SV=1
RTVLVASEEVMVSVTAHGYIKRTGLRSFSAST--GV--------ND-HVVFA-QQNTMDFVVVFTDKGNYVYRPVHELTD-----LGEHVSHLANA-DSE
R--AVLPLK---E-LAVVFTTANGMIKRSTLDQYQ----RSLTGVKLK-DSV-V----F--SDKVSLTTNKGYNL------V--ANVRTSGVKGINLK--
-DVIGAVKLAAH-DLLLVTQRGSVKRFNEK------RALRGLLML----RLPHRI-AMLSVA---SVTILTANDTTVDVEV-TVSV---YSNGSFVLDEI
D--AIAAWLNP-
>tr|W6A681|W6A681_9MOLU DNA gyrase subunit A OS=Spiroplasma culicicola AES-1 GN=gyrA PE=3 SV=1
EEELIQDTQMILTLTENGYIRRLTPEEFKTQKRGG-G--IN---ED-NIVISKMGKTKDDILFFSNEGKVYKIKGYNITQT-RTSRGLPIINFIGI-S-E
E--SVLPIK--K-FKYLVFITMNGVVKKVEINEFDR-N-YGKIAIHLD--DKLVS---SN---HILIASNKGKII------FRAMSRSSRGVKGMTLD--
-DVMTAVSDY-NDSIATISEYGIMKKTLI-EYN-FGRGAKGVVGM---NDKTGKK-SMLAIR-SDEILMISSQGKVIKIQV-DINL-SR---GVIGFNLE
D-YITATALEF-
>tr|A0A0K1W0N9|A0A0K1W0N9_9MOLU DNA gyrase subunit A OS=Spiroplasma litorale GN=gyrA PE=3 SV=1
EEELIQDEQFLLTLSNEGYVRRIKIEEIKTQKRGG-G--TN---ND-EITLSTIGKTKDEILFFTNIGKVYKIKAYKIDLS-KSSRGIPVINYIGI-E-E
K--SILCYK----SKNLFLITEKGIAKRVPIKEFER-N-FGKIAIILD--DKLIS---TE---NIMVASKKGKVL------FRTMSRSSKGVIAIKLD--
-GTISACSTI-NTMVVTISDKGILKKTLI-EYN-LSRGSKGVLGM---NDKTGKK-YIFSIR-TDEIIMISSEGRTIRILA-EINL-SR---GVIGFDVN
G-ALTSVSIKF-
>tr|A0A0K1P4M4|A0A0K1P4M4_9MOLU DNA gyrase subunit A OS=Spiroplasma turonicum GN=gyrA PE=3 SV=1
EEELIQDDQFLLTLTKDGYIRRIKLEEIKTQKRGG-G--LN---ED-EIIISTIGKTKDEILFFTNIGKVYKIKGYKIPIS-KNSRGIPLVNYIGI-S-E
K--SVLCYK----SENLFLLTEKGIAKRLSIKEFEK-N-IGKLVIILD--DKLVS---TE---NLLIASLKGKIL------FRTMSRGSRGVIAIKLD--
-DVVSACSTT-NTMIVTISDSGILKKTLI-EIN-LGRGSKGILGM---NEKTGNK-YIFSIR-TDEIIMISSDGKTIKLLA-DINL-SR---GVIGFDII
S-HVSSVSIKF-
>tr|A0A0M3SJ07|A0A0M3SJ07_9MOLU DNA gyrase subunit A OS=Spiroplasma cantharicola GN=gyrA PE=3 SV=1
DEELIQDTQMLITLSEDGYIRRLSNEEFKTQKRGG-G--IN---ED-NIAIAKFGKTKDDVLFFTDEGKVYRIKAYNITQS-RNARGVPVINFIGI-S-E
K--SILPLK--A-YKYLLFVTQKGVVKKVEIEEFNR-N-FGKIAINLD--DKLVS---TT---EILIASLNGKII------FRPMSRSSRGVKGMGLD--
-NVVSSCSSY-NESVATISEKGIVKKTLI-EYN-FGRGAKGVLGM---NEKTGKK-SLLAIR-TDEILMISSKGKIIKIGA-DINL-SR---GVIGFNLE
D-TITSTTLEW-
>tr|S5MDC2|S5MDC2_9MOLU DNA gyrase subunit A OS=Spiroplasma diminutum CUAS-1 GN=gyrA PE=3 SV=1
EEELIQDSQMLITLSGEGYIRRLSNEEFKTQKRGG-G--IN---DD-NIVIAKVGKTKDDVLFFSDEGKVYRIKAYNITQS-RNARGVPIINFIGI-S-E
K--SILSLK--I-YKYLLFITQNGVVKKVEIEEFNR-N-FGKIAINLD--DKLVS---TS---EILIASQNGKII------FRPMSRSSRGVKGMGLD--
-NVVSSCSSY-NECVVTISDKGIVKKTLI-EYN-FGRGAKGVVGM---SDKTGKK-SVLPIR-TDEILMISSKGKAIKIGA-DINL-SR---GVIGFNLD
D-YITAATLEW-
>tr|S5LVU9|S5LVU9_9MOLU DNA gyrase subunit A OS=Spiroplasma taiwanense CT-1 GN=gyrA PE=3 SV=1
DEELIQDTQMILTLSEEGYIRRLQPEEFKTQKRGG-G--IN---DD-NILIAKMGKTKDDVLFFSNEGKVYKLKGYNITQL-RTSRGVPIINFIGI-S-E
K--SVLTFR--N-YKYLVFVTKKGIVKKVNLEEFNK-N-FGKIAIHLD--DSLIS---TD---KILIATKNGKVS------FRPMSRSSRGVKGITLD--
-TVISSCTDF-NDCVVTISEKGIIKKTLI-EYN-FNRGAKGVVGM---NDKTGKK-SVLAIR-TDEVLMISSKGKIIKIHS-EIKM-SR---GVIGFNLE
D-KITAVTLEW-
>tr|W6A8X4|W6A8X4_9MOLU DNA gyrase subunit A OS=Spiroplasma sabaudiense Ar-1343 GN=gyrA PE=3 SV=1
NEELIADSKMIITLSKEGYIRRIEPNDFKIQKRGG-G--IND--TD-PITVATMGKTRDDLLLFTDKGKVYRIKAYNVTQS-RTSRGLPIINYINITD-E
T--SILPFR--NKYKFLTFVTKGGIVKRTPIEEFAL-N-SGKITIKLK--DELIS---TN---DLIIGTYKGKVT------INILSRSSFGVKGISLDK-
-DVIGSCT---SNLISTISDRGSAKKTSV-EYK-LGRNSKGVKAM---NEKTGFK-SILSIR--DTIVMISSKGNLIKIPV-ELPL-SR---GVKGFRLN
D-VITA-VTLE-
>tr|A0A0G0YJ22|A0A0G0YJ22_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWA2_42_14 GN=gyrA PE=3 SV=1
EEDLIPEEEIIIVLTKDGYIKRVKPETYRLQKRGG-G--IIE--ED-TVTHFITANTHSDLLFFTNYGKVYQIKAYEVPES-RVSKGKAIFNFL-SNN-E
A--SVLAAPKAPVSSYLVMVTKNGIIKKAEGTVFET-R-SGLIAIKLK--DTLQW---T---DELILATKLGKAI------VRPMGRNAAGVRAIRLGG-
-EITGMDIIPNNPQLLIVMENGYGKRSPV-QYK-QRRGGSGIKTA---TSKTGSV-SAQIIN-TTEIVAISQKGQAIRIPL-SIPI-GR---GVRIMKME
K-KIASITTL--
>tr|I0GJ27|I0GJ27_CALEA DNA gyrase subunit A OS=Caldisericum exile (strain DSM 21853 / NBRC 104410 / AZM16c01) GN=gyrA PE=3 SV=1
EEELIPDENIIVIVTRGGYLKRMREDVFKVQRRGGKGVIGQSV-QEDYPIEIIPTTLKSTMLFFTNIGKVYSLRAFEIPELERTGKGTPIHRLLKLLPNE
NISKVISIE---KIKSLLFVTRKGLVKKTKMEEFVYITSAGKIALKLKDDDELETVIPILEESDVMMISNAGLAVRFDT--VREMGRASSGVIGMKVK--
-FVVDAE--ILEDKVILVTEKGYGKILSVKEIRKTKRGAKGVKCI--SE-KTGNLVAVKVIHDEENLYLLLKSGNVIKIELKDVKELGRNTRGVILVRFK
-GDTVSAIALE-
>tr|A0A0P1P512|A0A0P1P512_9BACT DNA gyrase subunit A OS=bacterium JGI-24 GN=JGI24_01700 PE=4 SV=1
VEDLIAQEDVVITITHNGFIKRYPVSGYRRQNRGGRGITATAT-EDDFVEHMFVASAHHYIIFFTDKGKAYWLKVHEIPEGSRTSRGKSISYLVNKEP-E
KITAFVAVR----NLFVTMVTKMGYVKKVPLMEFSN-RRVGIIAINLNRGDRLVDAR-TDG-QDLIIGTKKGIAIRFNE--IRPMGRQATGVRGIKLE--
DEVIGMIAVKRGATILVVTENGFGKRSDLNDYRVTHRGGKGIIAVKVN-E-TGNMVAIKEVLN-DDIMIVTAKGYLIRHHVKDIRVMGRQAQGVKLIKLN
G-IIASVASVV-
>tr|O29785|O29785_ARCFU DNA gyrase subunit A OS=Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126) GN=gyrA PE=3 SV=
TTDLIEEEENAVLITAEGYAKRMSLEEFRVQSRGGVGVIGASV-PGDEIAVFRICNSTDRLLIFTNTGRAFWINAYEIPKMDRTARGTTLKRLIRLENGE
KVVSALGVK---NGKIAVILSPDGYIKKVPLIEFENAKRAGVKASAGE---IQ--QVELLEGDSIFIATANGNVVRLRE--VPEYGRNAKGVIAVRLR--
-RIAWMS--AS-EYLLMLTERGYGKRCDVNEFRFIGRGSMGMIGY--SE-KTGKLAFISACNG-EEVFIMSEDGYCIRIDSSTIPVQGRYSSGVVVARKG
-K----VALKK-
>tr|F8C3M9|F8C3M9_THEGP DNA gyrase subunit A OS=Thermodesulfobacterium geofontis (strain OPF15) GN=gyrA PE=3 SV=1
LEERVPKEFVLVLISKEGYIRKLSLDAFSSQKRGGKGALTFSL-ET--LKLALQVPSDSQLWVFTKKGKVYPLNLENIGFSTKTAKGTHIKNFIPYLEED
--ISFVL-P---EDAFLVLVTAKGIIKRIKISEMKNLRKSGSLVIKLRKDDYLKSGIVTNGDENLLIVTKKGLTIHFSE--IGITKKQSEGVLGIKLE--
-EVVEII--GTKKYLFTITERGFGKKTPIEEFRIQGRGGKGIIGH--TE-KSGYIAGAKGLTEEEDIIIFSSSGKAIRIEDKEIPEQKRATRGVRLISLL
-GYITGISVIQ-
>tr|A0A075X0G8|A0A075X0G8_9BACT DNA gyrase subunit A OS=Thermodesulfobacterium commune DSM 2178 GN=gyrA PE=3 SV=1
QEEKLPSEEVLFLISEEGYVRKLPLELFSPQKRGGKGSLAFTS-ER--LKVAIQTEATAVLWIFTEDGKVYPLDLRELSFSGKTVKGTYIKNLLPNLESP
--VSFVL-P---EEGFLVLATAKGIVKKLEIEELKNLRKNGLIVISLKKGDRLCKGVITNGNDRLLFLTKKGMSLHFEE--LGVTKRQAEGVVGIRLD--
-EVLGLI--KTQGYLFTITEKGFGKKTPFSDFRLQGRGGKGIIAH--NE-KTGYLADGVATFEKEDFVVFSSSGKAIRISSQDVPQQGRATKGVRIITLL
-GIVMGITPIR-
>tr|A0A0P1M077|A0A0P1M077_9BACT DNA gyrase subunit A OS=bacterium JGI-15 GN=JGI15_10385 PE=4 SV=1
IEDLIAEEDVVITITHNGFIKRYPVSGYRRQNRGGRGITATAT-EDDFVEHVFVSSTHHYIIFFTDKGRAYWLKVHEIPEGSRASRGRSISHLINKEP-E
KITAFVTVK----NLFVTMVTKMGLVKKVALSEFSN-RKIGIIAINLNRGDRLVDAR-TDG-QDLIIGTRKGMAIRFNE--IRPMGRQATGVRGVKLE--
DEVIGMVTVKRGTTILVVTEKGFGKRSDLNDYRVTHRGGKVIIAVKVN-E-TGDMVAIKEVLN-DDIMVVTAKGYLIRYHVKDIRVMSRQAQGVKLIKLN
G-TIASVASVV-
>tr|A0A0K8KKU2|A0A0K8KKU2_9FUSO DNA gyrase subunit A OS=Fusobacterium gonidiaformans ATCC 25563 GN=gyrA PE=3 SV=1
PEDLIKDEEMIITCTNKGYIKRIEANKYKSQNRGGKGVTGLNT-DDDVVDTILTASNLDTLMIFTDKGKVYNIKVYQLPES-RQSRGRLISNLLRIGEEE
KIRAIIKTR-F--EKELVFVTKQGIVKKTSLEEFKNINTGGLIAIKFKEEDDLIYVGLVEA-NEVFIATRKGFAVRFP---VRPTGRNTMGVKGIELR--
-EVVSALLIKEEMDILTITENGYGKRTRLDEYPSHNRGGKGVINLRCNE-KTGNIVSVLTAL-EEELVCITSNGIIIRTPMNSISR-SRAAQGVIIMKVA
-DKVASITRIK-
>tr|Q3A8P8|Q3A8P8_CARHZ DNA gyrase subunit A OS=Carboxydothermus hydrogenoformans (strain ATCC BAA-161 / DSM 6008 / Z-2901) GN=gyrA PE=3 SV=1
EEDLIAEEDMVITITHQGYIKRLPVDTYKNQRRGGRGVTAMAT-EEDFVRHLFVTSTHNYLLFFTNKGKVYRLKVHEIPEAGRQAKGTPIVNLLYVDQ-E
RITAIIPVK----DHYLFMVTKNGIVKKTVLSEYDS-RRDGIIALSLEEGDKLIDVK-STG-EEVIIGTKKGMAIRFSE--VRPMGRTARGVKGITLS--
-GVIGLEVVDEQAELLTVTSKGFGKKTPFSEYRVQGRGGKGIINMKVT-Q-NGEVVGIVAVRE-DEVMAISGEGIMIRVKAAEISTQGRATQGVTLMKLN
D-QLTAVAKIA-
>tr|A0A0F2Q535|A0A0F2Q535_9CLOT DNA gyrase subunit A OS=Clostridiaceae bacterium BRH_c20a GN=gyrA PE=3 SV=1
MEDLIADEDVVITISHTGYIKRMPTDTYKSQRRGGKGITAMTT-GEDFVEQLFITSTHNYLMFFTNKGKVYRLKVYEIPEASRQSKGTAIINLLYING-E
QITTVIPVK----NWYLFAATQKGIVKKTDLSEYDT-RKDGIIAISLADDDELMGVQ-TDG-QDVILVTKEGLSIRFNE--VRSMGRTAHGVRGIRLD--
-DVVGMDIIRNDSQLLVITDKGYGKRSPVEEYRTQSRGGKGIITLRIT-P-NGKLVGTKVVKG-EEIMIISKEGIIIRLKTDDISSMSRTTQGVLIMRVG
E-AVVAIARVV-
>tr|B2A2Z3|B2A2Z3_NATTJ DNA gyrase subunit A OS=Natranaerobius thermophilus (strain ATCC BAA-1301 / DSM 18059 / JW/NM-WN-LF) GN=gyrA PE=3 SV=1
EEDLIPDEEVIITLTHQGYVKRVPLSTYRNQKRGGRGISGMTT-NDDFVEHLFATSTHNYILFFTNKGKVYRLKVYEIPEASRQARGTAIVNLLAIDP-E
HITAVIPIQ----DDYLFFVTKQGVAKKVILSELKA-RKDGLIAINLNEDDELIDVH-TDG-QEIILGTEQGLAIKFSE--VRSMGRNSRGVKGISLK--
-NVIGMDIAQENSDLLIVSENGYGKRTPVSEYRTQSRGGKGIYTFKPS-E-SGNLAGCIVVND-EEIILVTAQGVINRQQVEGISQMSRRTQGVRLIKLK
D-QVVSLAIPE-
>tr|A0A085LA42|A0A085LA42_9FIRM DNA gyrase subunit A OS=Peptococcaceae bacterium SCADC1_2_3 GN=gyrA PE=3 SV=1
LEDLIPAEEEVITITNQGYIKRLSLNTYRNQKRGGRGVTAMGT-EEDFVRHLFIANTHHHVLFLTNKGKSYRLKVHEITEASRLARGTPIFNLLKFEP-E
KITTVIPVV----GKYIFMATRFGLVKKTPLESFKN-RRDGIIAVSLKPGDSLIGAK-TDG-QEIVLGTRRGLVIRFSE--VPAHGRTSRGVKGVTLK--
DIVVSMDVAQP-ASLLAVTANGYGKCTTLKKYRLQSRGGKGLISIRNN-V-NGPVVAFLVASD-EEIMLISAEGIVLRMKTTEINLTSRITRGVILMRLA
N-KIVDVTRVE-
>tr|A5D6F1|A5D6F1_PELTS DNA gyrase subunit A OS=Pelotomaculum thermopropionicum (strain DSM 13744 / JCM 10971 / SI) GN=GyrA PE=3 SV=1
EEDLIPEEDVVITITSQGYIKRIPLDTYRSQRRGGRGVTAMGT-EEDFVRHLFITTTHHFFLFFTNQGKVYRLKVHEIPEG-RQAKGTAIVNLLYIGS-E
KITTVIPVR---PAQYLFMATKRGIVKKTPLNEYDT-RRDGIIAISLNEGDHLVDVK-TGG-EEIILATRGGLAIRFLE--VRPTGRVTQGVKGINLV--
-DVVGMEVAR--EFLLSVTANGFGKRTRLSEYRAQARGGKGIINIKTT-A-NGPLVAIQAVKE-EEVMMISAEGIIIRLKAQDIPVMGRATQGVTLMRLD
GD-LVAAAKVE-
>tr|F6CIH8|F6CIH8_DESK7 DNA gyrase subunit A OS=Desulfotomaculum kuznetsovii (strain DSM 6115 / VKM B-1805 / 17) GN=gyrA PE=3 SV=1
AEDLIPEEEVVITITNQGYIKRMPLDTYRSQKRGGRGITAMGT-EEDFVRHLFITSTHHYFLFFSNRGKVYRLKVHEIPEAGRQAKGTALVNLIYIGP-E
RITAVIPVR----GLYLFMATRFGVVKKTQLEQFDT-RRDGIIAIKLDDQDELVEVK-TSG-EEIILGTRQGLAIRFPE--VHPYGRTARGVKGITLQ--
-GVVAMDIVRPDGDVLVVTANGYGKRTPVSDYRLQSRGGKGIISARVT-G-NGPVVAMQVVKD-EEIMVISAEGIIIRLKASDISTMGRATQGVMLMRLA
G-KLVAAALVS-
>tr|R4KD62|R4KD62_9FIRM DNA gyrase subunit A OS=Desulfotomaculum gibsoniae DSM 7213 GN=gyrA PE=3 SV=1
DEDLISEEDVVIAITNQGYIKRMPLDTYHSQRRGGRGINAMGI-DDDFLRHLFIATTHHYFLFFTNKGKVYRLKGYEIPEG-RQARGTAIVNLLYIDK-E
YITTVIPIR---NDYYLLMATRRGIIKKTPLNEYGY-KRDGIKALNLDDGDALVNAL-TDG-VEIIIGTQNGLAIRFSE--VRSTGRVTRGVKGITLN--
-HVVSMDLIR--SELLVVTSKGYGKRTKINEYRTQTRGGKGIINIKCT-E-NGLVVSLQVVKE-DEVLMISADGIMIRIKADDVSLFGRITQGVLLMKLG
GD-VVAVAKVI-
>tr|A0A0F2NAC9|A0A0F2NAC9_9FIRM DNA gyrase subunit A OS=Peptococcaceae bacterium BRH_c4a GN=gyrA PE=3 SV=1
PEAMIQEEDMVITITNQGYIKRIALDTYKSQRRGGRGITAMGT-EEDFVKHLFITSTHHFLLFFTNRGKVYRLKVHEIPEG-RTAKGTAIINLIQVEK-E
RITAVIPIK---EDLYLFMATRRGIVKKTQLIQYNT-RRDGIIAINLDEGDQLVEVK-TDG-QDIILGTRNGLAIHFFE--VQPYGRTARGVKGINLR--
-KVVAMDTLR--TDVLVVTANGFGKRTRTQEYKQQSRGGKGIINIKTS-A-NGEVVSLQVVRD-EEIMMISREGIIIRIQAKDVSLMGRSTQGVTLMRLD
GD-LVAVARVD-
>tr|C8VVA3|C8VVA3_DESAS DNA gyrase subunit A OS=Desulfotomaculum acetoxidans (strain ATCC 49208 / DSM 771 / VKM B-1644) GN=gyrA PE=3 SV=1
VEDLIAEEDMVITITRNGYIKRLPLDTYRSQKRGGRGISAMGV-EKDFLKHLFITSTHHYILFFTNKGKVYRLKVHEIPEAGRQSKGTAIINLLFVGT-E
KVTTVIPVK----DEFLFMCTKNGIVKKTSLNEFDT-RRDGIIALTLDDHDDLVDVR-TNG-EEIIIGTQKGLAIRFSE--VRKLGRIAKGVRGIGLI--
-GVVGMDTVRNEGDLLVVTKNGFGKKTPISEYRLQTRGGKGIINVKIS-D-NGPVVSLLVVKD-EEIMMLSSEGIIIRMKVNEISTTGRATQGVTLMKLS
G-SVATIAKVN-
>tr|B0TAN1|B0TAN1_HELMI DNA gyrase subunit A OS=Heliobacterium modesticaldum (strain ATCC 51547 / Ice1) GN=gyrA PE=3 SV=1
VEDLIAEEDAVITITHNGYIKRLPVNTYKAQRRGGRGVTGMGT-EDDFVEHLFVTTTHHTLLFFTDRGKVYRLKTHEIPES-RTAKGTAIVNLLAITG-E
KVNAVIPVK---ADQYLFTATRSGIVKKTSLQHYDT-RKEGLIALTLDEGDELIGVK-TDG-SDILLATRNGMAVRFNE--VREMGRTARGVKGIELT--
-GVVALDAVKD-DELLMITELGMGKRTPLSEYRKQNRGGKGILAMRLT-N-TGLMAGIKVVRG-DELMVISAEGVIIRLNVDEINVLSRVTQGVSIMRMN
ND-VVALARVA-
>tr|A0A0R1WXD5|A0A0R1WXD5_9LACO DNA topoisomerase IV subunit A OS=Lactobacillus hayakitensis DSM 18933 = JCM 14209 GN=FC40_GL000729 PE=4 SV=1
TEVMVAQEDIMLLVSHEGYVKRSSLRSFKASE--P---------ED-YPVLN-EQNTLDHLLMFTNKGNMVYRPVHEISD-----TGEHLSQSV-G-DDE
F--VAYTFK-L-AENDFIIATKHGYVKRIHLADIK----RASRFIKFK-DDQVIM---K---TEVFSVTNTGYGL------I--SGPQAIGVKNMDLR--
-DVAAVNLVKDDTVLSVLTQRGSFKNMQLS------RARRGVQIL----RLPHRV-NISNIY-LAHLVIITDKNEQIEIDP-DYPI---YSNGKFVLDVQ
Q--PQKYIIKD-
>tr|F7QVE8|F7QVE8_9LACO DNA topoisomerase 4 subunit A OS=Lactobacillus salivarius GJ-24 GN=parC PE=3 SV=1
TEVMVAQEDVMLLVSHDGYVKRSSLRSFNASD--N---------ED-YPILQ-SVNTLSHLFIFTNKGNLIYRPIHEVIE-----TGEHLSQTV-G-GDE
Y--NAFVFE-I-QDAKFLIATKEGYIKQVKLADLK----RASRYIKLK-VDEVIS------KSQVFCASYTGYGL------V--NGALAAGVKCMDLR--
-TLANVILVSESDEVSIITQRGSYKKMKVA------RARRGVQIL----RLPHRI-FAELVQ-NQELVLLLSDGKQETVKP-DHQL---YSNGSFVVDAE
D--ENIYTKII-
>tr|A0A0R1HJN5|A0A0R1HJN5_9LACO DNA topoisomerase IV subunit A OS=Lactobacillus algidus DSM 15638 GN=FC66_GL000216 PE=4 SV=1
TAVLITPEDVQVLVSHDGYLKRSSLRSFNASG--V---------ED-RIVFN-ESNTLDHLFMFTNKGNMIYRPIHEITE-----TGEHISQTI-G-DDE
Y--KAFSFK-V-APGKFVFATKNGFIKQTAVSDLQ----HASKFMKLK-DDDVIL---K--SLFIFSASHDGYGL------V--VGAKAAGVIAMNLK--
-DVASTCLVSENSQIGLLTQRGSFKRMSVS------RAKRGVLIL----RLPHKI-GVRPIT--VNLSVITESGNEFIVEP-SYPL---YSNGSFIIDTA
L--PILLSEIK-
>tr|Q9RT53|Q9RT53_DEIRA DNA gyrase subunit A OS=Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279
KEDLIAVEDMVITMTRAGYVKRTNLTAYREQKRGGRGSSGGKL-EEDANTGVFVGSTHDYLLFFTDQGRVFHEKIYDLPEAGRDAKGTHIRNLLPGR-DE
NIASVLSVS---QPGSFIFATKSGVIKKSLITDYANITSAGLIAINLQPGDELIGVD-QQDGDDVVLATKNGQAMRFEA--VRDTGRATQGVIGIRLR--
-EVVSMALVPGEGELLAISECGLGKRTKVSDYPSKGRGGLGVITL--TK--TGKLVTLAHVAGNEELMVLTEKGTVIRTRVEEVRVTGRNAQGVKVINIG
-KRVIDAFPIR-
>tr|A0A016QPF5|A0A016QPF5_9DEIO DNA gyrase subunit A OS=Deinococcus phoenicis GN=gyrA PE=3 SV=1
KEDLIAVEDMVITMTKAGYLKRTKLDAYRAQGRGGRGASGGKL-DEDINTRVFVGSTHDYLLFFTDAGRVFHEKIYDLPEAGRDAKGTHIRNLLPSR-DE
NIASVLSVK---EPGSFVFATRKGVVKKTLITDYGNITSAGLIAINLQPGDELIGVG-QRDGDHVVLATREGQAMRFAA--VRDTGRATQGVIGIRLR--
-EVVSMALVPGGSELLAVSECGLGKRTPVGDYPSKGRGGLGVITL--TK--TGKLVTLTHVAGDEELMVLTEKGTVIRTRVEEVRVTGRNAQGVKVINIS
-KRVISAFPIR-
>tr|A0A0F7JTJ7|A0A0F7JTJ7_9DEIO DNA gyrase subunit A OS='Deinococcus soli' Cha et al. 2014 GN=gyrA PE=3 SV=1
KEDLIAVEDMVITMTKAGYLKRTKLDAYRAQSRGGRGASGGKL-EEDVNTRVFVGSTHDYLLFFTDQGRVFHEKIYDLPEAGRDAKGTHIRNLLPSR-EE
NVASVLSVK---EAGCFIFATKNGIVKKTLITEYGNITSAGLIAINLQPGDELIGVG-VQDGDHVVLATRNGKAMRFES--VRETGRATQGVIGIRLR--
-DVVSMALVPGDSELLAVSECGLGKRTPVGDYPAKGRGGMGVITL--TK--TGKLVTLARVGGNEELMVLTEKGTVIRTRVEEVRVTGRNAQGVKVINIG
-KCVISAFPIR-
>tr|F2LWE3|F2LWE3_HIPMA DNA gyrase subunit A OS=Hippea maritima (strain ATCC 700847 / DSM 10411 / MH2) GN=gyrA PE=3 SV=1
IEDVIKDEQLIITFSKKGYVKAVPLDVYSTQHRGGKGRMA--A-DNDYITDIFLTNSLNTLLCFTNLGRVYSVKAYNIPKQSPSAKGRPIVNILNLQPQE
FVKTIVPIS----ADSLFFATAAGTVKRSSFRHFENIPSNGKIAIRLNEQDSLVSVFSVAEGDEVIITTRRGMCVRFDS--VRDMGRAAAGVRGINLS--
-SVVSAFNFNQ-TKLIVVSQTGLGKLLRVSDIRKVNRGAKGVRCI--KE--NDSVAGSLSLKDTGDVIVVTKNGKMIKMDADSINVFSRAARGVKLINLD
-ASVVSIVVAG-
>tr|W0JGQ7|W0JGQ7_DESAE DNA gyrase subunit A OS=Desulfurella acetivorans A63 GN=gyrA PE=3 SV=1
KEDLVKQEKLLITFSNKGYIKSIPLSFYNVQSRGGKGRIA--A-EDDYILDCLVLDSLDVVLMFSNNGRIYSIKAYEIPKSSNYTKGKAIVNLLNLKNNE
QIKTINAYK----GNDYVLITQKGIIKRISSDNFSDIKSNGRTIINLLNDDQLVCVINVSEKDEIIICTSLGQSVRFGI--VRKMGRNAYGVKGISLA--
-YVVSGFKLQN-EKIVLITQNGIAKVILADSIRKVSRGAKGVKII--KG--EDRLVDAERLQDNSEILITTKLGKLIRIDSNQFREMSRYAYGVKAIELE
-DSVVKVNVTK-
>tr|W8T3H0|W8T3H0_EUBAC DNA gyrase subunit A OS=Eubacterium acidaminophilum DSM 3953 GN=gyrA PE=3 SV=1
IEDLIEDEEIAITLTHLGYIKRVTSDTYKSQRRGGKGISALST-EADFVEHLVTTTTHSRVLFFTNKGRVYRIKAYEIPEK-RQAKGMALVNIIPLEK-E
KVTAIIPYI---AEKYLLLCTKKGIMKKTLLSEFRK-KRNGLIAINLRDDDELIGVK-TDG-QEIMLVTRKGMSIRFSE--IRPMGRSAMGVKAMTIP--
-DLVSISLVGE-DELLVVSEKGFGKRTLLDEYRLQSRGGKGIKTYNVN-E-TGFIAGSKTVND-DELMIISSDGVLIRLKVEGISQFGRATSGVKLMKTE
DA-IVSIAKIL-
>tr|A0A069RHV7|A0A069RHV7_CLOLI DNA gyrase subunit A OS=[Clostridium] litorale DSM 5388 GN=gyrA PE=3 SV=1
IEDLIEDDEITITLTHLGYIKRVTSDTYKIQKRGGKGISALST-EEDFVEHLVTTTAHSKVLFFTNKGRVYRLKAYEIPEK-RQAKGTALINILPLEK-E
KVTALIPFK---DENYLLLCTKMGIIKKTVLKEFRK-KRNGLIAINLRDEDELIGVR-TDG-QEIIMVTRKGMSIRFDE--IRPMGRSAMGVKGITLS--
-DIVSVNLVGE-EDLLIVSENGYGKRTLLTEYRMQSRGGKGIKTYNIN-P-TGSISGARVVNE-DDLMIINSDGVLIRLGVENISRLGRATSGVKLMKTE
ET-VVSIAKIM-
>tr|B1I1I1|B1I1I1_DESAP DNA gyrase subunit A OS=Desulforudis audaxviator (strain MP104C) GN=gyrA PE=3 SV=1
PEDLIPQEDAVIILTNDGYIKRMPPSVYRSQRRGGRGIAGVET-VQDFVRHLFVGKTHDYLLFFTERGKVYRVKVYEIPEAGRQARGTAVVNLIPVAN-E
RVTAVIPVT----DAFLFMVTRKGIVKKTVLQEFDS-RRDGLIALTLDEGDELVDVK-TDG-SEVLLGTRNGMVIRFPE--VRPMGRTAHGVRGISLR--
DMVVGMDIVDP-DQLLVVSEKGYGKVTPVKEFRVQSRGGFGLIAARVS-G-NGPLVSLSLVGG-EEILIVSKSGILIRMKIDEIPQFGRQAQGVRLMRLA
G-AVVAVAWIL-
>tr|C9RA74|C9RA74_AMMDK DNA gyrase subunit A OS=Ammonifex degensii (strain DSM 10501 / KC4) GN=gyrA PE=3 SV=1
PEDLIPAEQVVVLLSHQGYIKRQDKSLYRSQHRGGRGVTGLKL-DGDFVRHLYLANTHDYLLFFTSAGRVHRLKVYEIPEAERAGRGTALPNLLQLSP-E
QVTAIIPVA----DKYVLLVTRQGVVKKLPLGELAN-RRVGLNAISLDPGDELVAAA-PGP-EEVLLVTEGGKAIRFRA--VRPMGRAARGVRGMKLR--
DRVAGLAVLDG-GEVLLVTAGGYGKRVKTADFPLQGRGGMGVTALAVS-K-SGPVVGVEVVRE-EEILLASAAGWLTRLKVKEVPVMGRQARGVVLMRLQ
E-RLVALAKIG-
>tr|A0A0Q3U436|A0A0Q3U436_9BACI DNA gyrase subunit A OS=Bacillus sp. FJAT-21955 GN=AN962_16000 PE=4 SV=1
LEVMIASEDVYVTVTKDGYIKRTSQRSYAASN--G---------TD-RLIHQ-FENTTDVLLLFTNKGSYIYCPVHQLPD-----MGQHITNIISI-DDE
T--KAIPIK----SSYLLFFTKGGMVKKTELLQYK----KPLVALNLK-DEL-V----H--QQELFIATKNGYGL------V--VGPRAAGVKGINLK--
-DVVSGQIIDPNNVLVLTTQRGAVKRMNLS------RAKRGVIML----RLPHRV-AVIAAS---TLEIDTEKGATIPLDI-TLRA---YSNGSFILDEE
Q--VTQVLLSP-
>tr|A0A084H6W0|A0A084H6W0_9BACI DNA topoisomerase 4 subunit A OS=Bacillus sp. SJS GN=parC PE=3 SV=1
LEVMVASEDVIVTVTKDGYIKRTSQRSFSASR--S---------KD-RLISQ-LENTKDVLLLFTNKGSYLYCPVHSLPD-----MGQHIANIIPI-DNE
C--KAIPVK----HQYLLFITKNGMVKRTELTAYK----KPLVALNLK-DEL-I----H--QSEIFLTTHVGYGL------V--VGARAAGVKGISLK--
-DVISGQIFEKAPSILVVTQRGAVKRMDLT------RAKRGLIML----RLPHRM-GSFLTN---MIYLKTAKGLVESVRS-SYRN---YSNGSFAVDEH
A--VTEIWTNG-
>tr|A0A089LSP5|A0A089LSP5_9BACL DNA topoisomerase (ATP-hydrolyzing) OS=Paenibacillus stellifer GN=PSTEL_17135 PE=4 SV=1
LEALVNAEDVLVTLSAEGYIKRTSMLSFTRSG--GD--------GD-YVTKL-MDNTRDSLLIFTRKGQYFLLPVHQIPD-----PGTAIVNVIGL-SED
G--DVIPVS---PGLSLFFVTRKGQVKRTELKEYA----GAVAACKVA-DEV-L----L--DQDLMLITREGMSI------V--MGRVAGGVKGIQLR--
-DVAACFR-VSEGEVFVLSDLGYGKRSLLL------RGGKGVQTF--KGKVGSRA-GAFYCK---PVTAITKDGHIFELTT-SAPI---KSIGKLLVSLD
K--IIQVHRSV-
>tr|A0A089I9L3|A0A089I9L3_9BACL DNA topoisomerase (ATP-hydrolyzing) OS=Paenibacillus sp. FSL H7-0357 GN=H70357_23205 PE=4 SV=1
LEVLVNAEDVLVALSADGYIKRTGMPSFTRSG--GE--------GD-HIVKL-LDNTRDSLLVFTRKGQYFLLPVHQIPE-----PGTAIVNVISL-AGD
G--SVLPVG---PQASLVFVTRKGQVKRTELKEYS----GAVAACKVA-DEI-I----A--DKDIVLVTREGMSI------V--MGRVASGVRGIQLR--
-DVVSCFW-VSEGEILVVSDLGYAKRTLLV------RGGKGMPTF--KGKVGSRA-GAFHCK---ELVAFTRDGLHHQFSS-AAPL---RSTGKQLVPVE
K--IITLLPAI-
>tr|A0A0E3WIC4|A0A0E3WIC4_9BACL DNA topoisomerase (ATP-hydrolyzing) OS=Paenibacillus riograndensis SBR5 GN=parC PE=4 SV=1
LEVLVNAEDVLVALSADGYIKRTGMLSFTRSG--GE--------GD-HIVRL-MDNTRDSLLVFTRKGQYFLLPVHQIPE-----PGTAIVNVIGL-AGD
G--SILPVG---PGASLVFVTRKGQVKRTELKEYS----GAVAACKVA-DEV-L----A--DKEIVLVTREGMSI------V--MGRVASGVRGIQLR--
-DVVSCFW-VNEGEILAVTEIGYAKRTLLL------RGGKGMPTF--KGKVGSRS-GAFYCR---ELVAITREGATHSFSS-SAPL---RSIGKQLVSVE
K--IISLFPAI-
>tr|A0A089LU10|A0A089LU10_9BACL DNA topoisomerase (ATP-hydrolyzing) OS=Paenibacillus sp. FSL R7-0273 GN=R70723_20845 PE=4 SV=1
LEVLVNAEDVLVAMSADGYIKRTGMPSFTRSG--GE--------GD-HIVRL-LDNTRDSLLVFTRKGQYFLLPVHQIPE-----PGTAIVNVIGL-TGD
G--SMLPVG---PGTSLVFVTRKGQVKRTELKEYS----GAVAACKVG-DEI-I----S--DKDLVLVTREGMSI------V--MGRVASGVRGIQLR--
-DVVSCFW-VTEGEILAVTDIGYAKRSLLV------RGGKGMPTF--KGKVGSRA-GAFHCK---ELIAITRDGQVQTFSS-SAPL---RSIGKLLVSVE
K--IATIFPAI-
>tr|A0A089IPD6|A0A089IPD6_9BACL DNA topoisomerase (ATP-hydrolyzing) OS=Paenibacillus sp. FSL H7-0737 GN=H70737_20710 PE=4 SV=1
LEALVNAEDVLVALSADGYIKRTSMLSFTRSG--GE--------GD-HIVKL-LDNTRDSLLVFTRKGQYFLLPVHQIPE-----PGTAIVNVIGL-SGD
G--SVIPVN---PQQSLVFITRRGQVKRTELKEYS----GAVAACKVA-DEI-I----A--DKDIVLVTREGMSI------V--MGRVASGVRGIQLR--
-DVISCFW-VSEGEILSISDIGYAKRSLLV------RGGKGMPTF--KGKVGSKA-GAFYCR---ELNAITRENAHHTFSS-SAPL---RSTGKQIVPVE
K--IVNLFPAV-
>tr|A0A089HQV6|A0A089HQV6_PAEDU DNA topoisomerase (ATP-hydrolyzing) OS=Paenibacillus durus GN=PDUR_17080 PE=4 SV=1
IEALVNAEDVLVALSGDGYIKRTSMLSFTRSG--GE--------GD-YIASL-LDNTRDSLLVFTRKGQYFLLPVHQIPE-----QGTAIVNVIGL-GGD
S--GMIPVS---PDQSLFFITRKGQVKRTELKEYF----GAVAACKVA-DEV-L----M--DKDLMLVTKEGMSI------V--MGRVAAGVKGIQLR--
-DVISCFR-VSEGEVLAVTELGYGKRSLLL------RGGKGLPTF--KGKVGSRA-GAFYCR---ELTAITREGALYHFSS-AAPI---RSTGKLLVPLE
K--IISLQISV-
>tr|A0A098M6S5|A0A098M6S5_9BACL DNA topoisomerase (ATP-hydrolyzing) OS=Paenibacillus wynnii GN=PWYN_24540 PE=4 SV=1
LEVLVNAEEVLVALSSDGYIKRTSMLSFTRSG--SE--------GD-HIVKL-MDNTRDSLLVFTRKGQYFLLPVHQIPE-----PGTAIVNVISL-AGD
G--SILPVN---PQQSLVFITRKGQVKRTELKEYS----GAVAACKVA-DEV-I----A--DKDIVLVTREGMSI------V--MGRVASGVRGIQLR--
-DIIASFW-VSEGEILAITDLGYAKRTLLL------RGGKGMPTF--KGKVGSRA-GAFYCK---ELTAVTQDGLMHTFTS-SAPL---RSIGKQIVPVE
K--ILNILLTI-
>tr|X5A2E5|X5A2E5_9BACL DNA topoisomerase (ATP-hydrolyzing) OS=Paenibacillus sabinae T27 GN=PSAB_15460 PE=4 SV=1
LEALVNAEDVLVALSADGYIKRTSMLSFTRSG--GE--------GD-YITRI-LDNTRDSLLVFTGKGQYFLLPVHQIPE-----PGTAIVNVIGL-SGD
G--GIIPVS---PGRSLIFVTRKGQVKRTELKEYV----GAIAACKVG-DEV-L----M--DQDLVLVTREGMSI------V--MGRVAAGVKGIQLK--
-DVVACFR-VTEGEILVLSDIGYGKRSLLL------RGGKGVPTF--KGKVGSRA-GAFYCR---ELTAITREGEILSFSS-AAPI---RSTGKLLVPVV
K--IVSVQISV-
>tr|A0A0G1QAT3|A0A0G1QAT3_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWB1_45_9 GN=gyrA PE=3 SV=1
EEDLVPEEEVVITFSQSGYIKRLPPGTFRAQRRGG-G--ISE--ED-LITHFIQARTHDNILFFTDRGRVFQTKVYEIPQT-RTAKGKAVQNFL-EPQ-E
S--AIVSYK--ETNDYLVMLTQNGVIKKISLDEFDN-R-SGIIAIKLH--DALRW---SN---HIIITTAQGQGV------ARPMGRNASGVRAIRLRK-
-DASSLDIINK-AHLLVVTANGFGKRTLL-QFR-QRRGGSGTKAA---TAKTGQV-SAHVID-QEMLLAISAKGQIIKTNL-SVRI-GR---GVKIMNVR
S-KIAGVVCL--
>tr|A0A0G2BQ83|A0A0G2BQ83_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWA1_59_11 GN=gyrA PE=3 SV=1
DEDLIPQEEVVITLSAGGYIKRLPPSTFHAQRRGG-G--ISE--ED-FLAHFLAAATHDNILFFTDKGRVFQTKVYEIPAS-RTSKGRAIHNFL-EPD-E
N--ALVAYP---NDAALILLTQDGVAKRTMLEDFRN-R-NGIIAIALK--DRLKG---SG---QVVLTTEQGQSI------LRPMGRGAAGVRAIRLKK-
-GVAGFDIVRADQRLLVVMANGFGKQTPL-EYK-QNRGGSGIRTA---TAKTGEV-AAMVIS-EKEILALSKKGQMIRTEL-SVRT-GR---GVRIMNLK
T-RLAGVVVI--
>tr|Q67TK1|Q67TK1_SYMTH DNA gyrase subunit A OS=Symbiobacterium thermophilum (strain T / IAM 14863) GN=gyrA PE=3 SV=1
IEDLIADEDVVVTISHSGYIKRVPLSTYRQQRRGGRGVQGAGT-EEDFIEHIFTTTTHHDMMFFTDQGRVYRIRCHEIPES-RQARGTAIVNLIPLLP-E
KVNTVIPVK--QEEGYIFFATRSGWVKKTAVTEFQN-RSTGIIAIKLEEGDTLVGAR-TRG-DEIILVSSAGYALRFHE--VRPMGRDTRGVKGITLG--
-DVVGMDGVV--ADLLVVSETGVGKRTPLTEYPTYKRGARGVITIQLP-E-HGRLVGVKAVTG-NDLMLVSEQGVLIRIPVEEVRRSGRNTQGVQLMNLD
ND-VSAVAQVV-
>tr|Q2RMJ1|Q2RMJ1_MOOTA DNA gyrase subunit A OS=Moorella thermoacetica (strain ATCC 39073) GN=gyrA PE=3 SV=1
LEDLIAREDIVVTLTHRGYIKRQPVDTYRSQKRGGRGIQAMGT-EEDIVRDIFVTTTHHYLLFFTNQGRVFRLRGHEIPEG-RQARGTPLVNLLYLNK-E
TITAVIPIR---EDSYLLMATRKGIVKKTSLGEYHT-RRDGLLAINLDEDDDLVGVL-TEG-NEVMLVTRRGKAIRFGE--VRPMGRAARGVRGIALD--
-DVVGLVKVR--AELVVVSERGFGKRTTLEEYRPQGRGGKGIITMNVT-D-TGPVAAVAVVKE-DELMLISAEGILIRLGVEDISRQGRNTQGVTLMRLE
SD-VVAMARIQ-
>tr|A0A0M2U7E3|A0A0M2U7E3_9FIRM DNA gyrase subunit A OS=Clostridiales bacterium PH28_bin88 GN=gyrA PE=3 SV=1
VEDLIAEEDAVITITHRSYIKRTPVDTYRSQKRGGRGVTGVAT-EEDFVEHLFVATTHHFLLFFTNRGKVYRLKVHEIPEAGRQAKGTAIVNLLYLGG-E
KITAVIPVR----EKYLFMATRHGTVKKTALGEFDS-RRDGIIAINLDEEDELIGVH-TEG-QDIILGTRFGVAIRFPE--VRATGRNTRGVKGITLS--
-EVVSMDSVRPGADLLAVTENGFGKRTPLEEYRPQGRGGRGIIAIRTS-E-NGSLVAIMVVEG-DELMMVSSEGIIIRIDVADVSRMGRAAQGVTLMRLG
N-RVVAVARVP-
>tr|A0A0F2PLK8|A0A0F2PLK8_9FIRM DNA gyrase subunit A OS=Peptococcaceae bacterium BRH_c8a GN=gyrA PE=3 SV=1
DEDLIPEEDIVVTMTNHGYIKRMPVDTYRSQKRGGRGINAMGI-EDDFLRHLFIATTHNYFLFFTNRGRVLRLKGHEIPESGRQARGTAIVNLLYIDK-E
YITTVIPIR----DYYLLMGTRNGVIKKSSLSDYDS-RRDGIIALNLDEGDALVNVL-TDS-DDIIIGTKYGMAIRFAE--VRVTGRVTRGVRGITLR--
-GVVTMDRARDDSDLLVVTSNGYGKRSRLKDYRIQSRGGIGVTNIRCT-K-NGYVVSLHVIRE-EEVLMISSEGVMIRLKAGDISLIGRATQGVMLMKMG
G-HVVAVARVV-
>tr|A0A0C7NPV4|A0A0C7NPV4_9THEO DNA gyrase subunit A OS=Moorella glycerini GN=gyrA PE=3 SV=1
VEDLIAREDIVVTLTRRGYIKRQPVDAYRSQKRGGRGIQAMGT-EEDFVQDIFVTTTHHYLLFFTNKGRVFRLRGHEVPES-RQARGTPLVNLIYLNK-E
AITAVIPIR---EDAYLFMATRRGTVKKTPLAEYHT-RRDGLIAINLEDGDELIGVL-TEG-NEVILVTRQGKAIRFAE--VRPMGRAAHGVKGLALE--
-GVIGLVRVK--AELVVVSEKGFGKRTPLSEYRPQSRGGKGIITMNVT-E-TGPVAAVAIVTD-DELMLISADGILIRLGVEDISRQGRNTQGVTLMRLD
SD-VVAMARVQ-
>tr|B8E096|B8E096_DICTD DNA gyrase subunit A OS=Dictyoglomus turgidum (strain Z-1310 / DSM 6724) GN=gyrA PE=3 SV=1
IEDILPDNPEVICITQDGYIKRLPLSTYQLQRRGGKGLNTLAN-NDDVITSFVVTSTRSTLFLFSNKGKVYSIKTYELDES-RQSKGIAIKEYLNIENEE
RITEIISLS-L--NLYFFFITSKGIVKKTPVEEFENVRKSGIYAIKIGEGDFLVNVFLTSGNNEIIIFTRKGNAIRFH---TRPMGRVAQGVIGIKLR--
-SVIGGVILQESKQIVLVTKYGIGKRVNPQEFS-QKRGGIGIRAIKITS-KTGDLIGVKNVS-NDEILISTKKGQIIRIPVNNIP-LSRNSQGVKLVKLN
-DSVVSMDLVE-
>tr|B5YEN5|B5YEN5_DICT6 DNA gyrase subunit A OS=Dictyoglomus thermophilum (strain ATCC 35947 / DSM 3960 / H-6-12) GN=gyrA PE=3 SV=1
IEDILPDNPEVVCITQDSYIKRLPLSTYQLQRRGGKGLNTLAN-NDDVITSFVVTSTRSTLFLFSNKGKVYALKTYELDES-RQSKGVPIKEYLNIDNDE
KITEIISVN-F--NLYFFFVTSKGIVKKTSIEEFENVRKSGIYAIKLGEEDYLVNVFLTSGNDEIMIFTKKGNAIRFH---VREMGRIAQGVIGIKLR--
-SVIGGVIFKE-KQIVLVTTYGIGKRVNPNEFSVQKRGGMGVRAIKITP-KTGDLVGVKNVS-NDEILISTKRGQIIRIPVNNIPI-SRNSQGVKLVKLN
-DYVVSIDLVE-
>tr|A0A0M1QM06|A0A0M1QM06_GEOTC DNA topoisomerase 4 subunit A OS=Geobacillus thermoglucosidasius (strain C56-YS93) GN=parC PE=3 SV=1
LEVMIPSEDVIVTVTKEGYVKRTSYRSYNASN--G---------SD-RLLSQ-MENTTDVLLLFTRKGNYLYCPVYELPD-----VGQHISNLIPL-DDD
D--AAVPVK----PLSLVFVTKQGMVKRTELGQYK----RPLVAINVK-DEV-I----H--QQSLLLITNQGYGL------I--VGVRAAGVKGINLK--
-DVVSAHPIVAEQYLVIVTQRGAIKKMPL-------RAKRGVVML----RLPHRV-ASVLTD---MLFIRTETGEIETLSV-SLRV---YSNGSFIIDSD
A--VIDMWKQP-
>tr|R4F946|R4F946_9BACI DNA topoisomerase 4 subunit A OS=Anoxybacillus flavithermus NBRC 109594 GN=parC PE=3 SV=1
MNVVIPEEDVIVTITKDGYIKRTSLRSYSASN--G---------GD-RLLGM-FENTTHTLLLFTNKGNYLYCPVYELPD-----LGQHISHIIPL-DDE
Q--SAIPIA----GH-LLFITKQGFVKKTHLVHYK----KPLVAMRLK-DEV-V----Y--MGHIFLVTQYGYGL------I--VGVRAAGVKGIHLK--
-DVVSGQQATD-ENIILVTKRGAAKKIARA------RAKRGQLLV----KVPHRV-SCHFIS---WVILKTEKGITEEVHV-ELRL---YGNVTYVIDCD
T--VTDTWVKW-
>tr|A0A0K6GQ11|A0A0K6GQ11_9BACI DNA topoisomerase 4 subunit A OS=Anoxybacillus suryakundensis GN=parC PE=3 SV=1
MNVVIPEEDVIVTVTKDGYIKRTSLRSYSASN--G---------GD-RLLGM-FENTTHTLLLFTNKGNYLYCPVYELPD-----LGQHISNIIPL-DDE
Q--SAIPIV----GY-LLFITKQGLVKKTNLVHYK----KPLVAMRLK-DEV-V----Y--FGRIFLMTQYGYGL------I--VGVRAAGVKGIHLK--
-DVVSGQQATE-ENVVFVTKRGAVKKIART------RAKRGQLLI----KVPHRV-NCHFLS---HVVLKTEKGIIEEVNV-ELRL---YGNVTYVLDYD
V--VTDTWVRW-
>tr|A0A0A2SLA9|A0A0A2SLA9_9BACI DNA topoisomerase 4 subunit A OS=Anoxybacillus gonensis GN=parC PE=3 SV=1
MNVVVPEEDVIVTVTKDGYIKRTSLRSYSASN--G---------GD-RLLGM-FENTTHTLLLFTNKGNYLYCPVYELPD-----IGQHISNMILL-DDE
Q--SVIPVT----GY-VLFITKQGFVKKTSLVHYK----KPLVAIRLK-DEV-V----Y--TGRIFLVTQYGYGL------I--VGVRAAGVKGIHLK--
-DVVSGQQATE-ENVILVTKRGAVKKIART------RAKRGQLLI----KVPHRV-SCHFLS---YVILKTEKGITEEVYV-ELRL---YGNVTYVLDCE
A--VTETWVKW-
>tr|A0A023DDX7|A0A023DDX7_9BACI DNA topoisomerase 4 subunit A OS=Geobacillus caldoxylosilyticus NBRC 107762 GN=parC PE=3 SV=1
LEVMIPAEDVIVTVTKEGYVKRTSYRSYSASN--G---------SD-RLLAQ-LENTTDVLLLFTRRGNYLYCPVYELPD-----VGQHIANLIPL-EDD
D--AAVPVK----ALSLVFVTKQGMVKRTELAQYK----RPFVAMNLK-DEV-I----Y--KQSLLLVTNQGYGL------I--VGVRAAGVKGINLK--
-DVVSAHPVAGERYLVIATQRGAVKKMPL-------RAKRGVVML----RLPHRV-ASVLTA---TLFIRTETGTVETLSA-SLRS---YSNGSFIIDSD
A--VVDMWKAP-
>tr|C5DAU4|C5DAU4_GEOSW DNA topoisomerase 4 subunit A OS=Geobacillus sp. (strain WCH70) GN=parC PE=3 SV=1
LEVMIPAEDVIVTVTKEGYVKRTSYRSYSASN--G---------SD-RLLSQ-MENTTDVLLLFTRQGNYLYCPVYELPD-----VGQHISNLIPL-DND
E--AAVPVK----SLSLIFVTKRGMVKRTELAQYK----RPLVAMNVK-DEV-I----Y--QQSLLLVTNQGYGL------I--VGVRAAGVKGINLK--
-DVVSAHPIGKHMYLVIATQRGAVKKMPL-------RAKRGVVML----RLPHRV-ASVLTE---VLFIRTETGVTEMVST-SLRT---YSNGSFIIDSD
A--IMDIWKQP-
>tr|A0A0R2AW30|A0A0R2AW30_9LACO DNA topoisomerase (ATP-hydrolyzing) OS=Lactobacillus ozensis DSM 23829 = JCM 17196 GN=FD06_GL000614 PE=4 SV=1
NKITIPDETTVVLVSHDGYLKRSSLRSYKASE--V---------DD-YPIFL-KQSTRDHLFMFTNKGHLIYRPVFEITD-----TGEHISQTI-G-DDE
Q--NIFNFK---ENGMFVIATSDGYIKQTEFSKVI----HSLTYEKLK-QSKVVK---A--DAEIMIISNVGMAS------V--NGPRTTGVKSIELR--
-EVCNMEVVGD-DKIGIITQKGSYKNMLVN------RGRRGVQIL----TLSYEI-DFAKII-NIPLRIYTANSRIHDVLS-DYPM---KSNGSIIVDVK
E--PAKISEII-
>tr|A0A0Q6HJ44|A0A0Q6HJ44_9BACI DNA gyrase subunit A OS=Bacillus sp. Leaf13 GN=ASG65_25400 PE=4 SV=1
LEVLIASEDVMVTVTKEGYVKRTSLRSYSASG--G---------SD-RMLQR-LENTTDVLLLFTSKGNYLYCPVHQLPD-----TGQHIANIIPI-DEE
Q--KAIPIK----PQFLVFVTKNGMVKKTELASYK----KPLVGVNLK-DEL-V----H--QAELFLVTHNGYGL------V--VGVRAAGVKGINLK--
-DVIGGKVLA-KESILIVTQRGAIKKMKLT------RAKRGVVVL----RLPHRI-GFETVN---SLFILSEKGIIETIHA-SLKN---YTNGSFVFDET
S--AKELWKIS-
>tr|A0A0K9GUE1|A0A0K9GUE1_9BACI DNA topoisomerase 4 subunit A OS=Bacillus sp. FJAT-27997 GN=parC PE=3 SV=1
LEVLVASEDVIVTVTNEGYVKRTSLRSYTASG--G---------SD-RLLQK-FENTTDVLLLFTNKGNYLYCPVHQLPD-----TGQHIANIIPI-DDE
Q--KAIPVK----PDYLLFVTRNGMVKKTELSSYK----KPLVAINVK-DIL-V----H--SSDVFLATNLGFSL------I--IGVRAAGVKGINLK--
-DVTGGKILE-SEAILIVTQRGSVKKMKLT------RAKRGLVML----KLPHRI-GLETVI---TIFIETEKGVIESIHV-GLRY---YTTGSFVVDES
A--AKEIWKSS-
>tr|H1XV71|H1XV71_9BACT DNA gyrase subunit A OS=Caldithrix abyssi DSM 13497 GN=gyrA PE=3 SV=1
IEDLILEEDVVITISHMGFVKRISLNEYRTQNRGGKGITGAVT-DEDFVEHLFIANTHDYILIFTDRGKCYWLKVYAIPAGSRISKGRPIINLIDIES-E
KIKAVLPVK----EHFILMATRKGLIKKTNLSAFSR-RKSGIIALNIREDDELIEAK-SDG-RKVLYVTAHGKAIHFHE--VRPMGRGATGVRAIRLR--
DRVIAMVVAN-EMDLLTISELGYGKRTPIKEFRQQSRGGSGIIGMKVT-E-TGQLVGALGVYN-QDIVIITVKGIINRQNTINISRYGRSTQGVRLIRLT
G-RVSDVAKVS-
>tr|A0A0Q1AQ60|A0A0Q1AQ60_9DELT DNA gyrase subunit A OS=Desulfuromonas sp. SDB GN=APR63_02575 PE=4 SV=1
LEDLIKEEEVVITLTNRGYIKRLSSSTYKEQGRGGKGVIGSRS-SEDYVSSLSIATTHDYLLCFTDRGQLHWLRVYNIPEAARDARGRSLSNLLNLTK-E
TVKAVISVK---EDQYVFMATKKGIVKKCSLAEFSRPKKMSIRAISLSWDDELVEAN-TNGKDDIVLVTTNGKTIRFDE--VRQFGRNARGVIGIRLD--
-DVVSMMSFDKDISILTACQHGYGKLTKITEYPTQHRGGKGVIGI--SR--NGQVVISIPTQDDDGLILISQDGKVIRLAISDIRRIGRNTQGVRLMKLD
-GTLVGAAIIS-
>sp|D8K235|GYRA_DEHLB DNA gyrase subunit A OS=Dehalogenimonas lykanthroporepellens (strain ATCC BAA-1523 / JCM 15061 / BL-DC-9) GN=gyrA PE=3 SV=1
EEDLIPHQSMVVTLTERGFIKRVPTEVYRLQHRAGRGKSIIKT-EADSVRFIMVADTHDSVLLFTNRGKIFSIKCHEIPCLLRTAKGIAIINLV-PAENE
RITSMIAVS---EETSLIMATSGGECKRTKLSDFAAVRSSGLLAMDLPKNDELIGAV-AGADENIILITHNGRSIHFPV--LRVSQRASGGVRGITLE--
-DVAGLDVA--GHFVLVVTTGGYGKLTAVEEYPLQRRAGSGVLTF--VK--TGKVAAGKVVDREHQVMIATAEGVVIRTPVGGIIVMGRSTQGVIVIRPD
-NRVVNFATMV-
>tr|A0A076IJ47|A0A076IJ47_9CHLR DNA gyrase subunit A OS=Dehalococcoides mccartyi CG4 GN=gyrA PE=3 SV=1
VEDLVPHMDVIVTLSERGFIKRVPANVFRLQHRGGTGIMGMPT-EADAVRFLSVSDTHDTLLFFTNRGKVFSLRCFDIPDASRIAKGTAIVNLI-PTQDE
RITAILDLK---ADHFLLMATNKGEIKKTSLQEFTAVRSSGLIAMDLATSDELVAAV-TTEEKDILLATRMGQSIRFPV--LRTSLRASGGVKAIVLS--
-DVVSMDVA--GTLVITVTENGAGKLTAIEEYPQQHRAGSGVINF--VK--TGEVVASKVVSETDQMMLISADGMVTRTQVKGIPIMGRATQGVRVMRLE
-GRVVAVATF--
>tr|A0A0D6DX09|A0A0D6DX09_9LACT DNA topoisomerase 4 subunit A OS=Lactococcus piscium MKFS47 GN=parC PE=3 SV=1
AASLIVKEETIVSVTRSGYVKRTTPRSFGASK--L---------DD-VLLFH-QALTTQHLLMFTTLGNVIYRPIHELDD-----IGTHCSSLVNN-SDE
A--FAYILD---VTSQLLITTKFGLIKQVQLSDFR----KSLQFAKFK-DDIVIG---Q---LDIMLVTYNGYAL------V--VGPKAAGVKAMNLK--
-DIVASYFVST-DSFYVLTQRGALKRVKFN------RAGRGLQIL----RLPHKV-SSGAIKVMQVLQVISNTDTLFEINL-DLNV---TSNGSFIFDET
E--VKSSKIK--
>tr|I7LQ34|I7LQ34_9LACT DNA topoisomerase 4 subunit A OS=Lactococcus raffinolactis 4877 GN=parC PE=3 SV=1
AASLIVKEETIVSVTRSGYVKRTTPRSFSASK--L---------DD-SLIFH-QPLTTQHLLMFTTFGNVIYRPIHELDD-----IGTHSSSLVNN-SEE
E--FVQILD---ETRELMVSTKFGLIKKVALADFK----KSAQYAKFK-DDRVVS---K---ADMMLVTHNGYAL------V--VGAKAAGVKSINLK--
-DVVASYFADT-DSFYILTQRGSLKRVNFN------RAGRGLQVL----RLPHKF-ASGTVKTLQMLQVLSQTDKLFEINL-DLNL---TSNGSFIFDEA
E--VKLANIK--
>tr|A0A0M9DJT9|A0A0M9DJT9_9BACI DNA topoisomerase 4 subunit A OS=Lysinibacillus macroides GN=parC PE=3 SV=1
LDVLVPSEEVVVTVTKDGYIKRTSTRSHAASN--G---------SD-YLLYE-ATNTQHHLLLFTNRGNYIYQPVHELPD-----LGQHISSIVPT-GDE
A--AVYGFA---PNTYILTATKDGQIKRSPLVDYV----KPIKTMNVK-DTL-I----A--AVELMLTTDTAYAI------L--TGVKTGGVKGITLK--
-ELVGVNVLQPQ-YVVIVTQRGAVKKMNVA------RAKRGLKIL----TLPHRV-AIVQAT---QVVIETEKGMQEVLDV-ALTR---HSNGSFKVDVA
D--ISHVQIAK-
>tr|A0A078M3E2|A0A078M3E2_9BACI DNA topoisomerase 4 subunit A OS=Lysinibacillus sp. 13S34_air GN=parC PE=3 SV=1
LDVLVPSEEVIVSVTKDGYIKRTSPRSYSASS--G---------SD-YALFE-QPNTQHHLLLFTNRGQYIYQPVHELPD-----LGQHISSIVPL-EEE
E--AVHGFA---TTDFVMTVTEAGQVKRTVVADYK----RALKTMNVK-DAM-M----F--KDEVTLVTTEGQAL------V--TGLRTGGVKGMTLK--
-RIWADT---VE-RLIIVTQRGAVKKMGIE------RAKRGVQIL----SLPHQV-AVEKDR---LLVIETEKH-QEEIAM-DLPK---LSNGSFKVDPK
D--IRAVYHKM-
>tr|A0A0A3IEQ2|A0A0A3IEQ2_9BACI DNA topoisomerase 4 subunit A OS=Lysinibacillus odysseyi 34hs-1 = NBRC 100172 GN=parC PE=3 SV=1
LDVLVPSEEVVVTVTKDGYVKRTSQRSYAASN--G---------SD-YLLYE-ETNTQHFLLLFTSRGNYIYQPVHELPD-----LGQHISSIVSI-DNE
E--SVIGVD---EDTFIFTATKEGQIKRSALTDYV----KPIKTMNLK-DEM-I----E--KKEVLLTANTSFSI------L--TGVKTAGVKGILLK--
-ELAAANILEPQ-EVVIVTQRGAVKRMSVS------RAKRGVVTL----KLPHRF-TMIVVK---TILLETEKGIQEEIQV-SLSR---YSNGSLRVDTA
D--LVRVAVIK-
>tr|A0A0M0LJR8|A0A0M0LJR8_9BACL DNA topoisomerase 4 subunit A OS=Viridibacillus arvi GN=parC PE=3 SV=1
LEVLIPSEDVVVTVTKDGYVKRTSQRSYNASN--G---------SD-HLLYE-SQNTQQHLLLFTSKGHYIYQPVHELPD-----LGQHISSIVPI-DDE
V--NARGVE----DVFVMTITKGGQIKRSPLNEYV----KPIKTMNVK-DEV-I----D--TDEIILTTHFSYSV------V--TGVKTAGVKAINLK--
-DIVAANIIPEKGDLMLVTHRGAVKKMDVS------RPKRGVVTV----RLPHRF-TVIYVH---VLLVETEKGVQEQVHE-NYRN---YSNGSFVVDID
D--LTRVVKMK-
>tr|R7ZE83|R7ZE83_LYSSH DNA topoisomerase 4 subunit A OS=Lysinibacillus sphaericus OT4b.31 GN=parC PE=3 SV=1
LDVLVPSEEVVVTVTKDGYIKRTSTRSHAASN--G---------SD-YLLYE-GNNTQHHVLLFTNRGHYIYQPVHELPD-----LGQHISSIVPT-SDE
S--AVYGFE---PNTYILTATKDGQIKRSPLADYA----KPIKTMNVK-DEM-I----D--EAELLLITDTAYAI------L--TGVKTGGVKGITLK--
-ELVGVTILKPE-YVVIVTQRGAAKKMNVA------RAKRGLKVL----TLPHRV-AVIRAT---QILVETEKGVQEVIDV-GLTR---HSNGSFKVDIA
D--IAHVLKVK-
>tr|A0A0M8Q9B5|A0A0M8Q9B5_9BACI DNA topoisomerase 4 subunit A OS=Lysinibacillus contaminans GN=parC PE=3 SV=1
LDVLVPSEEVVVTVTKDGYIKRTSIRSHAASN--G---------SD-YLLYE-GNNTQHHLLLFTNRGNYIYQPVHELPE-----LGQHISSIVPT-GDE
S--KVFGFE---PNKYILTATKVGQIKRSPLADYA----KPIKTMNVK-DEM-I----D--EAELLLTTDTAYAI------L--TGVKTGGVKGITLK--
-ELVGVNILNPE-YVVIVTQRGAVKKMNVA------RAKRGLKVL----TLPHRI-AVVKAC---QLIVETEKGVQEVLDV-TLNR---HSNGSFKVDVA
D--ILHVLKEK-
>tr|A0A0A8JJW9|A0A0A8JJW9_BACSX DNA topoisomerase 4 subunit A OS=Bacillus sp. (strain OxB-1) GN=parC PE=3 SV=1
LDILVPSEEVIVSVTKDGYVKRTSVRSYSASN--G---------SD-YSLLE-GPNTQHHLLLFTSAGNYLYQPIHELPD-----LGQHISSIIPL-ENE
A--AAIGIE----DASIVTVSRNGMVKRSKLADFK----RTFRAMGIK-DAM-V----R--DEDILLFTHGSYAL------L--TGVRTAGVRGINLK--
-DIVAAEFIQ-A-SILLATQRGSVKRMNLN------RAQRGVVVL----KLPHRV-GAKLVK---TIILATEKDEKVPVVA-SLRL---YSNGSAIIDEK
Q--VKTIYKET-
>tr|A0A0M4G0U2|A0A0M4G0U2_9BACI DNA topoisomerase 4 subunit A OS=Bacillus sp. FJAT-22090 GN=parC PE=3 SV=1
LDVLIPSEEVIVTVTKDGYIKRTSMRSFTASN--G---------SD-YLLYQ-EPNTQHHLLLFTSKGNYIYQPVHELPD-----LGQHISSIIPL-DNE
S--NVIGIE----DLCVLTATKEGQIKRSLLSDYV----RPIKTMNLK-DEL-I----Q--SDDVLLTTYHSYSV------V--TGVKTGGVKAINLK--
-DVVSVNVISQE-DITLITHRGSVKKMGLK------RAKRGIVTL----RLPHRF-AVILTN---EIVLETEKGVQEVVQT-SLRP---YSNGSFIVDTE
D--LVRVWKQP-
>tr|A0A0M0W969|A0A0M0W969_9BACI DNA topoisomerase 4 subunit A OS=Lysinibacillus sp. FJAT-14745 GN=parC PE=3 SV=1
LDVLVPSEEVVVTVTKDGYIKRTSTRSHAASN--G---------SD-YLLYE-ANNTQHHLLLFTNRGNYIYQPVHELPD-----LGQHISSIVPT-GDE
S--AVYGFE---ANTYILTATKDGQIKRSPVADYA----KPIKTMNVK-DEM-I----D--EVELMLTTDTAYAI------L--TGVKTGGVKGITLK--
-ELVGINVLPPA-YVAIVTQRGAVKKMNVA------RAKRGLKVL----TLPHRV-AVVKVT---QLTIETEKGVQEILDV-ALTR---HSNGSFKVDIA
D--ISHVFAVK-
>tr|A0A0A3I2B9|A0A0A3I2B9_9BACI DNA topoisomerase 4 subunit A OS=Lysinibacillus manganicus DSM 26584 GN=parC PE=3 SV=1
LDVLVPSEEVVVTVTKDGYIKRTSTRSHAASN--G---------SD-YLLFE-SMNTQHHLLLFTNKGNYIYQPVHELPD-----LGQHISSIVPL-ESE
E--EVIGIE---ENIFILTATKLGQIKRSLLTEYA----KTIRTMNIK-DEM-V----S--GKDLLLTSYQSYTI------L--TGVKTGGVKGMNLK--
-DLVSINSIEKH-DLIVITHRGAIKRMSSS------RAKRGVVIL----KLPHRF-AVITVK---TIKIITENNVEESFIV-SFAK---YSNGSLKLDVS
D--PLYFKVIT-
>tr|A0A0A3JSX9|A0A0A3JSX9_9BACI DNA topoisomerase 4 subunit A OS=Lysinibacillus massiliensis 4400831 = CIP 108448 = CCUG 49529 GN=parC PE=3 SV=1
LDVLVPSEDVVVTVTKDGYVKRTSIRSHAASN--G---------SD-YLLYE-ATNTQHHLLLFTNKGNYIYQPVHELPD-----LGQHISSIVPI-ESE
E--EVIGIE---ENTFILTATRSGQIKRSPLSEYA----KPVRTMNLK-DEM-I----G--NKEVLLTSYLSYSL------I--TGVKTGGVKGMNLK--
-DLVSVNMLNKQ-DIMVITHRGAVKRMSVS------RAKRGVVTL----KLPHRY-AVIAVD---TIKITTAKHIEETLAV-SFTK---YSNGSLKIDVS
D--LVLVKVLP-
>tr|S2XV88|S2XV88_9BACL DNA topoisomerase 4 subunit A OS=Paenisporosarcina sp. HGH0030 GN=parC PE=3 SV=1
LDVLIPSEEVMVTVTKDGYVKRTSTRSYSASN--G---------SD-YLLFE-SMNTQHHLLLFTSLGNYIYQPIHELPD-----LGQHISSIVSL-DNE
T--KAIPIE----NRYILAVSKLGQIKRSTLVEYQ----RALNTMNLK-DQV-M----D--TEDVFIVTHNGYAV------V--TGVKTGGVKGINLK--
-DVANATIIPAG-DLFLVTHRGAVKKMALK------RAKRGVVVL----RLAHRS-GVFYVE---QVIIETAKGVREVVDT-PIRV---YSNGSFIVDTD
D--VVRLWKAL-
>tr|A0A0A3HQS9|A0A0A3HQS9_9BACI DNA topoisomerase 4 subunit A OS=Lysinibacillus sinduriensis BLB-1 = JCM 15800 GN=parC PE=3 SV=1
LDVLVPSEEVVVTVTKDGYVKRTSTRSHAASN--G---------SD-YLLFE-ETNTQHYLLLFTNKGNYIYQPVHELPD-----LGQHISSIVPI-EDE
E--EVIGIE---ENVYVLTATKEGQIKRSSLADYA----KPIKTMNIK-DEM-I----Q--ETEVMLTTNMSYCL------I--TGVKTGGVKGINLK--
-DLTAVNLLHPQ-EVVIVTHRGAVKRMNVS------RAKRGVVVL----KLPHRF-DVKVVQ---TVLLETEENITEMIGV-NLSK---YSNGSLKIDVS
D--LLRVKVMP-
>tr|E6VSG3|E6VSG3_DESAO DNA gyrase subunit A OS=Desulfovibrio aespoeensis (strain ATCC 700646 / DSM 10631 / Aspo-2) GN=gyrA PE=3 SV=1
IEDLIPDEETVVTLSQRGYIKRTPLSNYTAQRRGGKGISGVQT-DGDFIHTFMLTTNHQHLVLFTNLGKMFKIKAHQVPEGSRYAKGGHVANLL-PDKDE
CITTALSLR---DDRFFLFLTKKGMIKRSSIGLYGNCRSTGIRAVNLRDGDELMMVR-IEPDVDCILVTRDGSAIRFNI--ARPLGRTTAGVKGVALR--
-DVVACVVTGDRDQLLTVSAGGFGKRTGIDQYRQQSRGGKGILNM--TK--TGKVVGARMVNESDDVILLTSANKIIRMSVSEVSQRGRATQGVRLVRMD
-NSVIGFELVM-
>tr|A0A068JLN7|A0A068JLN7_9DELT DNA gyrase subunit A OS=Desulfonatronum thiodismutans GN=gyrA PE=3 SV=1
MEDLVGDTEVVITLSQRGYIKRTPMDTYQQQKRGGRGIYGAST-SEDIISQMFTTTNHNFILLFTNKGRMYKIKAYNIPEGSRTARGVHASNLL-PDKDE
FIATAMTIK---TDKDFLFATKRGVVKRSQAQLYVNCRQSGLKAVNLHPEDELITVR-ISTSAEVVLITKHGKSIRFSS--IRSTGRATAGVKGMDLN--
-DVVSCVVTDDREEVLTVSANGYGKRTLIENYRSQSRGGKGVINM--TK--TGNVVGSVLVQAEDDLLILTSAGKIIRMNVAGISRVGRDAQGVTLVRMD
-DSVVGFDRVD-
>tr|F0JIQ5|F0JIQ5_DESDE DNA gyrase subunit A OS=Desulfovibrio desulfuricans ND132 GN=gyrA PE=3 SV=1
IEDLIPDEETVITLSRRGYIKRTPLSNYTAQKRGGKGIAGVQT-DGDFIHTFMLTTNHQHLVLFTNFGKMFKIKVHQVPEGSRYAKGGHVNNLL-PDKDE
HIATCLSLR---DDRFFLFVTKKGMIKRSSIGLYGNCRTTGIRAVNLRDHDELMDVR-IEPEVDCILVSREGSAIRFNI--ARPMGRATAGVKGMALR--
-DVVACVVTGDRDQLLTVSEGGYGKRTTIDQYRVQTRGGKGILNM--TK--TGMVVGACMVNESDDVILLTSQNKIIRMSVSEVSQRGRATQGVRLVRMD
-DKVIGFDLVM-
>tr|D9TMD0|D9TMD0_THETC DNA gyrase subunit A OS=Thermoanaerobacterium thermosaccharolyticum (strain ATCC 7956 / DSM 571 / NCIB 9385 / NCA 3814) GN=gyrA
IEDLVQLEDAVVTMTHFGYIKRMPLDAYKSQKRGGKGISGIST-EDDFVENVFTTTTHDRLLFFTNKGKVYSLRTIDIPESGRQAKGTAIVNLIQIDQ-E
KVSAVIPIK----AKYVVMCTKKGIIKKTEIDDFPK-KKSGNTAIKLDDGDELINVM-TNG-REIIIGTANGYCIRFHE--LRPMGRQARGVIAISLR--
-DVVEMDLINEDNEILVVTENGYGKRSDVKEYRSQTRAGKGIIATKIT-Q-TGKLVSIMSVSK-DELMIISANGILIRTRIADISKMHRDASGVTLMKLD
G-RVVSTAKID-
>tr|D3T539|D3T539_THEIA DNA gyrase subunit A OS=Thermoanaerobacter italicus (strain DSM 9252 / Ab9) GN=gyrA PE=3 SV=1
LEDLVQLEDVVVTMTHYGYIKRMPLDTYKAQKRGGKGILGIST-EDDFVRDIFITTTHDRLLFFTNKGKVYSLRTIDIPETGRQAKGTAIVNLIQIAQ-E
KVTAVIPLK----IKYVVMCTKKGIIKKTSIEEFRS-KRNGIIAITLEENDELINTK-TNG-REIIIGTAKGYAIRFNE--IRPMGRVAKGVIAISLR--
-DVVEMDLVHPGSEILVVTEKGFGKRTDLEEYRLQTRAGKGIIAIRLS-E-TGKLVSIRSVNE-DEFMIISANGILIRMKVSEISKMHRDTRGVTLMKLD
G-RVVSTARIE-
>tr|F3A9N5|F3A9N5_9BACL DNA gyrase subunit A OS=Gemella sanguinis M325 GN=gyrA PE=3 SV=1
NEDLIEKEQIIITLSHNQYIKRLAASTYKSQGRGGRGVNGMTT-DEDNVAYMLSCSTHDHILFFTDKGKVYTLKGYEINQS-RQSKGIPIINLLEIEK-E
KVNSIIAIS--EEGTSLMFSTRFGIVKKSKLGDYAS-LKKGKIALKLDEGDSLIDVQ-ITD-QDIMIVTANGQAIRINA--VRQMGRVSRGVKGITLS--
-DVIGMEVVDE-KKILTVTENGIGKISKSTEFNVINRGGKGVKVAKVT-K-TGKIVAVKSV-G-EDLMIMTDQGIIIRIDVSAISTLGRTATGVKVINLV
DQ-VATVTLAA-
>tr|Q0SN74|Q0SN74_BORAP DNA gyrase, A subunit OS=Borrelia afzelii (strain PKo) GN=gyrA PE=3 SV=1
MSDLMQKENIVVMLTKKGFLKRLSQNEYKLQGG--KS-------GD--EIAIALCNSHDYLFMISNEGKLYLINAYEIKDS-RASKGQNISELI-NGQ-E
E--TIKNSK--TDDSYLLLTTASGKIARFESTDFKT-K-RGVIVIKLN--DFVTS---F--DEKVICLSKKGSAF------VR-LNRGTQGVCGMKLKG-
-DFVKVLA---NPYLLIISENGYGKRLSVS-IS-EKRGATGYTSY--SK-KAGSV-AIA-VS-DDEILLVSKRSKALRTVA-KVSE-GK-ARGIQVLFLD
D-SLISVSKFI-
>tr|S5Z4C8|S5Z4C8_9SPIR DNA gyrase subunit A OS=Borrelia miyamotoi LB-2001 GN=gyrA PE=3 SV=1
MSDLMQRENVIVILTKKGFIKRILQDEYKLQGG--KG-------GD--QVNIALCNTHDFLLMISNEGKLYVINAYSIKDS-RTSKGQNVRELI-NGM-E
R--AIKNSN--SVNNYLLITTAKGKIARIETESFKT-K-RGVIVIKLD--DFVTS---S--DEKVICISKKGNAF------IR-LHRGTQGVSGMKVRG-
-DFVKALV---GSHLLIVSENGYGKRLEIS-VT-GKRGATGYTSY--SE-KAGEV-AIT-VS-DDEVLLISETSKVLRTLV-KISE-GK-ARGMQVISLD
D-KLVSVSKFI-
>tr|W5SMM6|W5SMM6_BORAN DNA gyrase subunit A OS=Borrelia anserina BA2 GN=gyrA PE=3 SV=1
MSDLMQRENVIVILTKQGFIKRILQDEYKLQGIGG-G--SFE--RD-QVNIALCVNTHDFLLMISNEGKIYVINVYGIKDS-RTSRGQDIRKLV-NGT-E
E--AIKNCN--SVNNYLLITTANGKIARIGTEDFKT-K-RGVIVIKLD--DFVTS---VE---KVICISKKGNAF------IRLTHRGTQGVSGMKVRE-
-DFIKALA---GSHLLVVSENGYGKRLEI-KVS-LKRGATGYTCY---DEKAGAV-DAITVA--DEILLVSKSSKILRTLV-KISE-GK---GMQVLSLD
G-KLIS-VSKF-
>tr|B5RRN7|B5RRN7_BORRA DNA gyrase subunit A OS=Borrelia recurrentis (strain A1) GN=gyrA PE=3 SV=1
MSDLMQRENVIVILTKQGFIKRVLQDEYKLQGG--KG-------SD--QVNVALCNTHDFLLMISNEGKLYVINAYGIKDS-RISRGQNIRELI-NGK-E
E--AIKNCS--SVDNYLLITTANGKIARIETEGFKT-K-RGVIIMKLD--DFVTS---S--DDKIICISKKGNAF------IR-LHRGTQGVSGMKVRG-
-DLIKALA---GSHLLIMSENGYGKRLEVS-VT-GKRGSTGYTCY--SE-KAGEV-AIT-VS-DDEILLISKSSKVLRTLV-KISE-GK-ARGMQVLSLD
D-KLVAVSKFI-
>tr|A0A0H4LCT4|A0A0H4LCT4_9LACO DNA topoisomerase 4 subunit A OS=Lactobacillus farciminis GN=parC PE=3 SV=1
TSVMVASEDVRLLVSHDGYVKRSSLRSYQASS--P---------ED-YPIID-QNNTLDHVFIFTDKGNLIYRQIFEIED-----TGSHLSQQV-G-DDE
S--KAFVFK---ETGNFLIATNENYIKQVAFSDLL----RASKYCKIK-DARVMN---A--SDLVYVFTKHSYAS------V--VSGKAIGVKFVSLK--
-DLAGYFLSTDNEKIALLTQRGSYKQMKLS------RARRGVLTL----RLPHRQ-LVTNIS---SISIITDANKEIEIDR-GHQS---YSNGSFIMDPE
D--PVRFVKKI-
>tr|A0A0R1JVI7|A0A0R1JVI7_9LACO DNA topoisomerase IV subunit A OS=Lactobacillus alimentarius DSM 20249 GN=FC67_GL001784 PE=4 SV=1
TKVMVASEDVRLLVSHDGYVKRSSLRSYQASD--P---------ED-YPIAD-MNNTLDHLFIFTDKGNLIYRQIFEIED-----TGSHLSQKV-G-DDE
S--KVFVFK---ETGNFLVGTDENYIKQVAFSDLL----RASKYCKLK-VSRVLA---P--QKLIYVFTKHSYAS------V--VSGKAMGVKFVSLK--
-DLAGYFLADDNDKIAVLTQRGSYKQMKLS------RARRGVLTL----RLPHRC-LVTNIN---NLSIITDTNKEIPVDI-IHQN---YSNGSFIMDPV
D--PIRFVKKI-
>tr|A0A0R1KMQ5|A0A0R1KMQ5_9LACO DNA topoisomerase IV subunit A OS=Lactobacillus nodensis DSM 19682 = JCM 14932 = NBRC 107160 GN=FD03_GL001975 PE=4 SV=1
TSVLVASEDVRLLVSHDGYVKRSSLRSYQASD--A---------ED-YPILD-QENTLDHLFIFTDNGNMIYRQIFEVDD-----TGSHLSQEI-G-ADE
S--KAFVFK---EKGTFLIGTSENYIKQVAFSDLL----RASRYSKLK-DAKVMD---P--NGQIYVFTEHSYAS------V--VGSKAVGVKFVSLK--
-DLAGYFLSTDSDKIALLTQRGSYKQMKLS------RARRGVLTL----RLPHRS-LVTNIS---QLSVVTDTNQEISLDE-SHQN---YSNGSFVMDPE
D--PIRFVKNV-
>tr|A0A0R1QUF4|A0A0R1QUF4_9LACO DNA topoisomerase IV subunit A OS=Lactobacillus mindensis DSM 14500 GN=FD29_GL001878 PE=4 SV=1
TRVMVASEDVRLLVSHDGYVKRSSLRSYQAST--A---------ED-YPIID-TNNTLDHVFIFTDKGNLIYRQVFEIED-----TGSHLSQVI-G-DDE
S--KAFVFK---ETGNFLIGTNENYIKQVSFQDLL----RASKYCKLK-TGRVFD---D--KNLIYVFTKHSYAS------V--VSGKAIGVKFVSLK--
-DLAGYFLAGDSEKIALLTQRGSYKQMKLS------RARRGVLTL----RLPHRC-LVTNIT---DISIMTDANQEIAIDR-SHQS---YSNGSFIMDPA
D--PVRFVKKI-
>tr|A0A0R1I5X8|A0A0R1I5X8_9LACO DNA topoisomerase IV subunit A OS=Lactobacillus paralimentarius DSM 13961 = JCM 10707 GN=FC97_GL001005 PE=4 SV=1
TKVMVASEDVRLLVSHDGYVKRSSLRSYQASD--A---------ED-YPIID-ENNTLDHVFIFTDKGNLIYRQIFEIED-----TGSHLSQEI-G-DDE
S--KAFVFK--EETGNFLIGTNENYIKQVAFSDLL----RASKYCKLK-TSRVMD---P--KKLVYVFTEHSYAS------V--VSGKAMGVKFVSLK--
-DLAGYFLATNNDKIAVLTQRGSYKQMKLS------RARRGVLTL----RLPHRC-LVTNIS---QLSIVTDSNKEIEIDP-MHQN---YSNGSFIMDPE
D--PLRFVKKM-
>tr|H3SBL1|H3SBL1_9BACL DNA topoisomerase (ATP-hydrolyzing) OS=Paenibacillus dendritiformis C454 GN=PDENDC454_04486 PE=4 SV=1
LEVIVNAEDVIVTLSNEGYIKRTSLLSFTRSG--GE--------GD-YIRHV-FENTLDRLLLFTQRGQYFSLPVHLLPE-----NGTAIVNVIPI-GED
R--SVIPVK---EHSSLLFVTRRGQVKRTLLKEYE----GAIAACKVA-DEV-L----L--SHDLMLVTKLGMSI------V--MGRAAGGVRGIQLK--
-DIAAALQ-VMEGEITVMSDLGWGKRSLLL------RGGKGIATF--KGKVGSRI-GAFFSK---PITFITDAGHAHTLLT-QAPL---KAQGRSLVPMD
G--IAAAVVIG-
>tr|K4ZG81|K4ZG81_PAEAL DNA topoisomerase (ATP-hydrolyzing) OS=Paenibacillus alvei DSM 29 GN=parC PE=4 SV=1
LEVIVNAEDVLVSLSNEGYIKRTSQLSFTRSG--GE--------GD-YIRQI-NENTLDRLLIFTQRGQYFSLPVHMIPE-----NGTAIVNVIPI-AED
S--AAIPVK---EQSSLLFVTRRGQVKRTMLKEYE----GAVAACKVA-DEL-L----M--SADLLLVTEQGMAI------V--MGRAAGGVRGMQLK--
-DITAALQ-VTEGEITVLTDIGWGKRSLLL------RGGKGMATF--KGKVGKKI-GAYFSK---PITIITEQGHLHQLIT-HAPL---RAQGRSLVTLD
E--IVNTTVII-
>tr|K0J2W5|K0J2W5_AMPXN DNA topoisomerase 4 subunit A OS=Amphibacillus xylanus (strain ATCC 51415 / DSM 6626 / JCM 7361 / LMG 17667 / NBRC 15112 / Ep01
LEVTVASEDVLVSVTRDGYVKRTSLRSYAASN--E---------GD-YLVGL-YENTTDDLLIFTNQGRYIFAPVHQLPD-----LAQHLSSLANL-EGE
K--NAIPIR----GQYLVFFTREGMVKRSELSLYE----RPLVALNLR-DQL-I----A--LQDLFVVSNRGFGL------V--VGQRAAGVKSINLK--
-EVVSGLVLEGDTHFTLVTQRGAMKRMKVT------RTNRGQVML----RLPHRV-GFIEVR---EVNVLTENGVLQTVHP-ELSI---YSNGSFILDTD
V--VTQAWKKV-
>tr|B6G1U2|B6G1U2_9FIRM DNA gyrase subunit A OS=[Clostridium] hiranonis DSM 13275 GN=gyrA PE=3 SV=1
VIDLIDEEEIAITLTHFGYIKRLPADTYRSQKRGGRGISALTT-EEDFVKHLISTTTHSRLLFFTNRGRVFRLNAYEIPEGKRQAKGTAIVNLLQLGP-E
KIATLIDVD---ENKYLLIATKKGMVKKTKISDFKN-NKSGLISIGLKEGDEVIGVK-TDG-QDVMLVTRNGMSIRFSE--VRGMGRTAMGVKGITLG--
-GVVSMSLASEGTDMLVVSENGFGKRTDLEEYRSQIRAGKGIKTYNIS-E-TGSIVGAEMVAD-DEMMIINSDGVLIRIKVNEISIFGRVTSGVKLMNVD
E-SIVSIAKIT-
>tr|W1WKX8|W1WKX8_9ZZZZ DNA gyrase subunit A OS=human gut metagenome GN=Q604_UNBc4C00015G0006 PE=3 SV=1
IKDLIDDEEITITLTHFGYIKRLPLDTYKSQRRGGRGISALTV-EEDFVKHLITTRTHNRLLFFTNRGRVFRLDAFEVPEGKRQAKGTAIVNLLQLGP-E
KIATLIEVD---DDSYLLLATKKGIVKKTKRSEFKN-NKSGLIAIGLRDDDELIDVK-TNG-KDVLLVTSNGMSIRFDE--IRPMGRTAMGVKGITLS--
-GVVSMSLSDEGEDLLVVSQNGYGKRTDINEYRSQIRAGKGIKTYNMS-E-TGEIVGATMVNE-DELMLINSDGVLIRLRVDDISVFGRITSGVKLMKTD
E-NVVSIAKID-
>tr|A0A0L0W7N5|A0A0L0W7N5_CLOPU DNA gyrase subunit A OS=Clostridium purinilyticum GN=gyrA PE=3 SV=1
IEDMIQEEDVAITLTHFGYIKRLPEDTYKTQRRGGRGVSGMTT-EEDFVEHLFITSTHDNILFLTNQGRVYRLKAYEIPEAKRQAKGTAIVNLLQLNP-E
KVTAVIPIK----DDYLTLVTEKGIIKKTKLDKFGN-RKNGLIGISLKEDDELISAK-TNG-NDIILVTSYGMSIRFNE--VRDMGRTAGGVKAITLK--
-GIVGMDLIEEGKDLLVISERGYGKRTKISSYRIQTRGGKGLKTYNIK-EITGKLISAKIVDE-DEVMLISLSGTIIRLKVSDISRMGRTTQGVRLMKTD
D-RVVSVAKVI-
>tr|E0E1L5|E0E1L5_9FIRM DNA gyrase subunit A OS=Peptostreptococcus stomatis DSM 17678 GN=gyrA PE=3 SV=1
LKDLYEEEEIAITLTHLGYIKRLPADTYKSQKRGGRGISALTT-EEDFVTDLISTTTHSLMLFFTNRGRVYKLNAYEVPEK-RTSKGTAIVNLLQLNP-E
KIARTISFN---DLKYLLFATKSGIVKKTPISDFKN-NKSGLIAINLKDGDELIGVN-TNG-EDIILVTENGMSIRFNE--VRSMGRTATGVKGITLS--
-GVVSMDLISN-TDLLVVSEKGFGKRTETEEYRPQIRAGKGIKTYNIN-S-TGKLVGATLVDD-DEMMMINSNGVLIRIRVNEISIFGRVTSGVKLMKTD
EV-VVSIAKLK-
>tr|R5JIY4|R5JIY4_9FIRM DNA gyrase subunit A OS=Peptostreptococcus anaerobius CAG:621 GN=gyrA PE=3 SV=1
VKDLFEEEDVAITLTHLGYIKRLPADTYKSQKRGGRGISALTT-EEDFVRELISTTTYSTILFFTNRGRVYRLNAYEVPEK-RTSKGTAIVNLLQLNP-E
KVARTITFN---ESDYLLLATKNGIVKKTQISEFKN-NKSGLIAINLKDGDELIGVN-TDG-QEVVLVTENAMSIRFNE--VRPMGRTATGVKGITLS--
-DVVSMNLIGE-DNLLVVSQNGFGKRSDVEEYRPQIRGGKGIKTYNIT-S-TGKIVGSSLVND-DEMMMINSNGVLIRIRVNEISIFGRITSGVKLMRTD
EV-VVSIAKIK-
>tr|T2GA48|T2GA48_DESGI DNA gyrase subunit A OS=Desulfovibrio gigas DSM 1382 = ATCC 19364 GN=gyrA PE=3 SV=1
IEDLIPDDEVILTLSRRGYIKRTTLDNYRVQGRGGKGVAAVQT-DGDFIHTFCATSNHQTLLLFSNKGRMYSVKVHQVPEGSRTAKGMHIANLL-PEREE
WIATALTMR---ETRALLFVTRKGVVKRSEATLYSNVRRAGIIALNLREDDELIMVR-VGDTDECVLTTQKGLAIRFPV--VRLMGRASAGVKGMTLA--
-DVVAGVILKAVQEILSISSNGYGKRTLIEHYRLQSRGGKGVINM--TK--TGDVIGAMPVSESDELILLTTANKAIRTSVREISLVGRATQGVRIVRMD
-KSVAAFDLVR-
>tr|C7M119|C7M119_ACIFD DNA gyrase subunit A OS=Acidimicrobium ferrooxidans (strain DSM 10331 / JCM 15462 / NBRC 103882 / ICP) GN=gyrA PE=3 SV=1
AEDLIEDEPIVVLISRSGYIKAVPESSFKAQGRGGRGVVGARV-DEDEIAHVISSSMLSRLLVFSSRGRVYQLRGYELPKLERSARGTALVNLVPLADDE
RITSVMGTK---EDADLVFFTRNGMVKRTAMAEYARSRRDGIIAIDVRGDDELVSVVVATEEHDGVVFTKRGQVLRFPL--VRRTGRATAGVRSIRRA--
-WIVAGGLI--GVEVLLVTSRGYGKRTPLDSFPVHHRGGAGIRGI--TE-RKGELVAAAFVRPEDEVLIVSSQGQMIRVRIGDISNQGRYATGVKLISLQ
-ESVASVGVVP-
>tr|A0A0R2RZJ8|A0A0R2RZJ8_9ACTN DNA gyrase subunit A OS=Acidimicrobiia bacterium BACL6 MAG-121220-bin61 GN=ABR76_03260 PE=4 SV=1
VEDLVDDKELVIVMTQAQYIKAVSADSFRTQGRGGRGVSGAKM-TDDIVRNVIFTTSHAYLLFFSNRGRVYRLRALEIPERERTAKGIPIVNLLPLQPGE
TIQAIIDTR---GERFLFFATKQGQVKKTAFDEYNSSRRDGLIALKLRPKDELVRVIETSGTDDVFMVTKGGQTIRFAE--VRPMGRSAAGVRGMKLR--
-EVVALDIA--DSAILLITESGYGKRTQLTNFARKGRGGLGMIGI--TG-KKGSVVAAFMVGLEDDIVVVASGGTTIRTPVKEISSQGRAATGVRIMSLG
-GVVASAALVL-
>tr|B3ESJ9|B3ESJ9_AMOA5 DNA gyrase subunit A OS=Amoebophilus asiaticus (strain 5a2) GN=gyrA PE=3 SV=1
LEDMIAEEDMVITISQQGYIKRTPLSEYRIQNRGGVGARSTAT-EDDYITHLFVASTHQYLLIFTTLGKVFWKKVYTLPEGSKSSKGRAIQNLIPIAPGD
QVQSVIKVRK--NSRYILMCTVQGVIKKTPLDAYIN-RTNGIQAIKINEGDRLLTVKLTKGDNHVIIALRSGRAIHFH---VRSMGRVSTGVRGITLAP-
-DVVGMVTVYKDIELLVVAEKGVGKRSAVADYRITKRGGKGVKTLNITE-KTGALAAIEAVT-ADELLIINTSGIAIRIEVSTLRIMGRNTQGVRLIRLN
-GAITSIAKIT-
>tr|A0A0B5I0G6|A0A0B5I0G6_9ARCH DNA gyrase subunit A OS=archaeon GW2011_AR15 GN=gyrA PE=3 SV=1
IEDLIDEEDVVVTISHSGYIKRMSLDEYKQQGRGGKGIRGAET-EEDFLEHLFIANTHSFLLTFTNKGRVYWTKVYRIPDASRYSKGKAIVNLVGLEQ-E
KISAVIPVK----NEYLVFATTGGLVKKTRIRAYSK-RKGGIWAINLREGDDVISVV-TNG-KQLILATKEGMAVKFNE--VRPVARHSFGVRGITLK--
GDVIGMVVA--DRTLLTITENGFGKRSPISDYRLINRGGSGVINIKTN-E-NGGVIVIKSVSE-DELMLISVNGQVIRTSAKFISVIGRNTQGVRLMRLN
-GKVADAARIL-
>tr|M7NHM5|M7NHM5_9BACL DNA topoisomerase 4 subunit A OS=Bhargavaea cecembensis DSE10 GN=parC PE=3 SV=1
LDILIPSEDVVVTVTKDGYAKRTSLRSYGASG--G---------TD-RLLFG-GTNTQQTLLVFTSSGNYIYQPVHELPD-----LGQHISSIIQL-SEE
E--AAFGVD---EDIDVVTVTKGGFIKRSALADYQ----RAYKAVSLK-DVL-Q----H--TDEVLLFTHLAYGL------V--TGVRTAGVKGINLK--
-DVVSSVLRSPR-SLILATHRGAVKRMPVN------RAKRGLVSL----KLPHRV-GVALAG---TVILRTDKDAEVAVLP-SYRM---YSNGSFAVDQK
D--VTSVYLAV-
>tr|F9DMZ2|F9DMZ2_9BACL DNA topoisomerase 4 subunit A OS=Sporosarcina newyorkensis 2681 GN=parC PE=3 SV=1
LDILVPSEEVMVSVTKGGYIKRTSMRSYSASN--G---------SD-YNLLE-AANTQHHLLLFTSSGNYIYQPVHELPD-----LGQHLSSIVGL-ENE
E--DVIGLE----NLSILTAASNGNVKLSKLTDFQ----RSFKAMNVK-ETL-V----Q--KEDVLLVSKQAYAL------L--TGIRTGGVRGLHLK--
-DLVAFEVIT-K-NIFVATQRGSVKRMNIS------RALRGVTVL----KLPYRV-DMKAVK---QFVLLTTKDQKIEIDP-LLKN---QSTGSSIVDEA
E--IVQVAVMK-
>tr|B9L8W8|B9L8W8_NAUPA DNA gyrase subunit A OS=Nautilia profundicola (strain ATCC BAA-1463 / DSM 18972 / AmH) GN=gyrA PE=3 SV=1
IEDLIPNEEMVVTITHRGYVKRVPLKAYERQNRGGKGKALT-I-EDDFIEDFYVANSHDTLMIITDRGQLHWLKVYRIPEGSRTSKGKAIVNLINLDKDE
KIQTIIKTE---ESKSLAFFTKNGIVKRTNLSEFKNIRSTGVRAITIDEGDELVTAK----DKELFIVTKKGMAIRFP---VREMGRTARGVTGIRFKE-
-DVVGALALQDNQEILTLSEKGFGKRTEANLYRLTNRGGKGVIAMKLT--KTGDLVGVVA-E-DHDLMVLTSSGKMIRVSIDSISKTGKNTQGVRVVKLD
--KVVSLAKTP-
>tr|A6DA14|A6DA14_9PROT DNA gyrase subunit A OS=Caminibacter mediatlanticus TB-2 GN=gyrA PE=3 SV=1
IEDLIPNEDMVVTITHRGYVKRVPLKTYERQNRGGKGKALT-T-ENDFIEDFYIAKAHDTLMIITNKGQLHWLKVYKIPEGSRTSKGKAIVNLINLDKDE
KIQTIIKTS---ENKSLAFFTKNGIVKRTNLSEFKNIRSTGVRAIVIDKDDELVTAK----DKYLFIVTKKGMAIRFP---VREMGRNARGVKGITFKE-
-DVVGALSLRDKQEILSVSEKGFGKRTEAEAYRLTNRGGKGVIAMKLT--KTGDLVGVVA-E-NHDLMLLTSKGKMIRVSIDSISKTGKNTQGVRLVRLD
--KVVSVAKTP-
>tr|T0IPH5|T0IPH5_9FIRM DNA gyrase subunit A OS=Sporomusa ovata DSM 2662 GN=gyrA PE=3 SV=1
MEDLIAEEDIVITLTHQGYIKRLPVDTYRSQRRGGRGVHGMGT-EEDFVEHLFVATTHHNLLFFTSRGRMYRLKGYELPEAGRTAKGTAIVNLLQVEK-E
KITAVIPIK----KRYLFMATQKGTVKKSELLEFDT-RKGGLIAISLDEDDDLIGVK-TNG-YDIIMGTRDGKAIVFHE--VRIMGRTAHGVKGITLD--
-DVIGMDVVKKDGEVLTITSEGYGKRTNANDYRITGRGGKGVINIKPA-E-IGYVIGIKIVKG-QELMLITSEGIVIRMEIDTISITSRSTQGVKVMRTD
E-KVVALAVVE-
>tr|A0A0K8JJ17|A0A0K8JJ17_9FIRM DNA gyrase subunit A OS=Propionispora sp. Iso2/2 GN=gyrA PE=3 SV=1
VEDLIAEEDIVLTLTHGGYIKRLPVDTYRSQKRGGKGVTGMGT-EEDFVEHLFVTTTHNNILFFTSRGRVYKLKGYEIPEASRTARGTAIVNMLALEQ-E
KITAVIPVK----RRFLLMVTQKGIVKKTELMEFDT-RKGGLIAINLDDDDDLIGVR-TSG-HYVIIGTKGGLAIYFPE--VRPMGRSAHGVKGITLQ--
-GVVGMDTVKKDGELLTVTSEGYGKRTPLVEYRNQSRGGKGVINIKVT-E-TGHVVGIKVVKG-QELMLITGDGIVIRTDIDAISVFSRNAQGVKIMRTG
T-TVVALAVVE-
>tr|A0A075KP51|A0A075KP51_9FIRM DNA gyrase subunit A OS=Pelosinus sp. UFO1 GN=gyrA PE=3 SV=1
VEDLIAEEDIVLTLTRSSYVKRLPVDTYRNQKRGGRGVAGMGT-EEDFVEHLFVTTTHHNILFFTNRGRVYRMKGYEIPEASRTSKGTSIVNLLPLEG-E
RITAVIPIR----TRYLFMATAKGIVKKTELMEFDT-RKTGLIAISLDEDDDLIGVK-TNG-QHVLMGTSDGLAIYFPE--VRHMGRTARGVRGIRLH--
-GVVDMDTLKQDGEVLTVTAEGYGKRTPVDNYRNQKRGGKGVINTKVT-E-TGKVVGIKVVRG-QELMLISSEGIVIRIDIDTISVISRNTQGVKLMKTG
N-KVVALASVE-
>tr|F7NQC7|F7NQC7_9FIRM DNA gyrase subunit A OS=Acetonema longum DSM 6540 GN=gyrA PE=3 SV=1
VEDLIAEEDIIITITHNGYIKRMPIDTYRSQKRGGRGVTGMGT-EEDFVEHLFIATTHHNILFFTNQGRVYRLKGYEITDAGRTAKGTAIVNLVPLEG-E
LITAVIPVK----QRYLFMTTRNGIVKKTEVIEFDT-RKGGLIAIILDEGDDLIAVK-TNG-QEVIIGTSEGIAIRFSE--VRTMGRSSRGVKGISLE--
-TVIGMEVATKGTEIMTVTAEGYGKRTAVDEYRVQTRGGKGVINHKVT-D-TGQVIGIKMIKG-QEIMLISTDGIIIRMEADEIPTQGRSTQGVRMMRIG
N-KVGALAVVD-
>tr|H3K8T3|H3K8T3_9FIRM DNA gyrase subunit A OS=Megamonas funiformis YIT 11815 GN=gyrA PE=3 SV=1
IADLIAEEDVVITLTHNNYIKRIPVTTYRNQKRGGRGVTGMGT-EEDYVENMIITSTHNTILFFTNKGLVYQLKGYEIPESGRTAKGTAIVNLLPLAK-E
TITAIIPIK----DRYLFMATRHGIVKKTGLSEFDTRKKTGLIALSLKENDELIGVK-TDG-RQIIIGTRDGMSICFNE--VRPMGRTARGVIGIKLK--
-EVIGMDNIRDDCEVLTVTEHGFGKRTATSEYRTQTRGGIGLINIKVT-E-TGFVIGIKVVDQ-QEFMLISTEGIVIRSNIEEVSVIGRNTQGVKMMNMD
N-KVAALAAFE-
>tr|E3PQZ2|E3PQZ2_CLOSD DNA gyrase subunit A OS=Clostridium sticklandii (strain ATCC 12662 / DSM 519 / JCM 1433 / NCIB 10654) GN=gyrA PE=3 SV=1
ILDTIPDEEVTVTFTHYGYIKRIPMDTYKAQRRGGKGITSMTT-DDDFVEKLLLTTNHSLILFLTNRGRIYRLNAYEIPQG-RIAKGTNIVNLIPLEK-E
KVTSFISIR---AENYLVMCTKKGVIKKTQISEFRK-TRNGLIAISLREDDELINVK-TDG-QDFIIVTKKGMAISFDE--VRDMGRAAMGVRAIRLA--
-DVVAMELVDP-KQLLVISEKGYGKRTNTKDYRLQTRGGKGVKTYKIS-E-TGILVGAKAVYD-EEIMIINSDGSLIRMSVNQISILSRVTSGVKVMRTD
NS-VVALARIV-
>tr|D6GSU6|D6GSU6_FILAD DNA gyrase subunit A OS=Filifactor alocis (strain ATCC 35896 / D40 B5) GN=gyrA PE=3 SV=2
IKDMIPDDEVTVTLTHLGYIKRVGIDTYKTQKRGGKGIASMST-DEDFVDKLLLTSNHSKVIFFTNMGRIYRLNTYEIPE-SRTAKGTNIVNILPLEDGE
KVNTMLSIR-EASSGFVVMCTRKGIMKKTPLEEFQRSNRNGLIAISLKEDDELIGVELTDGNCNIICVARNGKAIMFD---IRSMGRTAQGVRAMNLE--
-EIVSMMIA--EKDVLIISERGYGKRTPIAEYNLQTRGGKGSRTYKITE-KTGRLVGGKVVS-DDEIMIVNIDGTLIRMEVKGISV-SRVTSGVRLMKTA
-NDIASFEKIE-
>tr|M1ZFI8|M1ZFI8_9FIRM DNA gyrase subunit A OS=[Clostridium] ultunense Esp GN=gyrA PE=3 SV=1
IEDMIEEEDVIITLTHYGYIKRMPQDTYKIQRRGGKGITGLTT-EEDFVENLFITSTHDTILFFTNKGRVYSLKAYEIPER-RQARGTAIVNLLNLTG-E
SISAVIPIE---PKSNLVFITKNGLIKKTKLSNFKN-RRNGIIAISLKEEDELIAVR-TNG-RQIIVVTSMGMSIRFSE--VREMGRNAMGVIAIRLK--
-DVVAMDLIEE-KDLLVVSEFGFGKRTPLDEYRIQNRGGVGIKTYNVK-D-TGKLVSAKVTDN-DEIIMISMSGIIIRLISKGISSMGRNTQGVTLMKIN
ENKVMAVAKYV-
>tr|R2QCM9|R2QCM9_ENTMU DNA topoisomerase 4 subunit A OS=Enterococcus mundtii ATCC 882 GN=parC PE=3 SV=1
TQVLVAQEDVIVSVTREGYVKRTSLRSYSASK--P---------GD-YLLYA-GENTLDHLLLVTNKANVIYRPVHELPD-----AGEHISQTIVN-ADE
S--AVFPYQ----EKTFVFISKNGLIKQTRMTDFE----RPLSGMKLK-EDELVA---K--DRDIFLVTHQGMGL------V--VGTKAAGVKSINLKE-
-YVVNGLLVLADTPIVIVSQRGAVKRMLAQ------RAKRGVTVL----RLPHRI-YMSEGH---TMTLINQKGQELPIDP-DYPI---TSNGSFVLDEK
G--VQMVIDSP-
>tr|D4QH32|D4QH32_ENTFC DNA topoisomerase 4 subunit A OS=Enterococcus faecium E980 GN=parC PE=3 SV=1
TQVLVAQEDVIVSVTREGYVKRTSLRSYSASK--P---------GD-YLLYS-GESTLDHVLLITNKANVIYRPVHELPD-----AGEHISQTISN-SDE
S--AVFPYQ----EKTFVFISKNGLIKQTRMTEFE----RPLSCMKLK-EDELIA---E--GLDVFLVTHQGMGL------V--VGAKAAGVKSMNLKG-
-RIVNGLLVLADTPIVIVTQRGAVKRMLAQ------RAKRGVTVM----RLPHRI-YMSEGR---EITLMNQKGQQITIDP-DFPI---TSNGSFAMDEK
G--VIEVIDAP-
>tr|S4E228|S4E228_ENTFL DNA topoisomerase 4 subunit A OS=Enterococcus faecalis 13-SD-W-01 GN=parC PE=3 SV=1
TEVLVAQEDVVVSVTKEGYIKRSSLRSFSASK--P---------GD-RLMYA-GENTLDHLLMITNKANVIYRPIHELPD-----VGEHISQTISG-SDE
S--AVFPYH----EKTFVFISRNGMIKQTRMTEFE----RPTSGMKLK-DDQLAA---N--DLDVFLVTNQGLGL------V--VGAKAAGVKSMNLKE-
-YIVNGMLVLADTPIVIVTQRGAVKRMLAQ------RAKRGVLVL----RLPHRI-YMSEGI---ELTLINQKGQQAAIDP-DFSI---RSNGSFAMNEK
G--VIEVIEDY-
>tr|R2S295|R2S295_9ENTE DNA topoisomerase 4 subunit A OS=Enterococcus villorum ATCC 700913 GN=parC PE=3 SV=1
TKVLVAQEDVIVSVTKEGYVKRTSLRSYSASK--P---------GD-YLLYA-AENTLDHLLLITNKANVIYRPVHELPD-----AGEHISQTILN-SDE
S--AVFPYK----EKTLIFISKNGWIKQTRMTEFE----RPLSGMKLK-DDELVA---E--DLDVFLVTHQGMGL------V--VGAKAAGVRSINLKA-
-TVVNGLLVFADAPIVLVTQRGAIKRMLAQ------RAKRGVTVL----RLPHRI-YMSEGN---ERTLVNQKGQELVINP-DYPI---TSNGSFVLDEK
G--VIQVIDTA-
>tr|A0A0K1XMS8|A0A0K1XMS8_9ENTE DNA topoisomerase 4 subunit A OS=Enterococcus durans GN=parC PE=3 SV=1
TKVLVAQEDVIVSVTREGYVKRTSLRSYSASK--P---------GD-YLLYS-GENTLDHLLLVTNKANVIYRPVHELPD-----AGEHISQTILN-SDE
S--AVFPYK----EKTFVFISKQGWIKQTRMTEFE----RPLSGMKLK-DDELVA---D--GLDVFLVTHQGMGL------V--VGTKAAGVKSINLKE-
-IVVNGLLVIADTPIVIVTQRGAVKRMLAQ------RAKRGVTVL----RLPHRI-YMSEGK---EMTVINQKGQELVIDP-DYPI---TSNGSFAMDEK
G--VIKVIVSP-
>tr|A0A0M2PKN7|A0A0M2PKN7_9BACI DNA topoisomerase 4 subunit A OS=Bacillus sp. SA1-12 GN=parC PE=3 SV=1
LEVMVASEDVIVTVTKDGYVKRTSQRSYAASN--G---------SD-RLLSQ-IENTTDVVLLFTNKGNYLYCPVHELPD-----LGQHIGNIIPI-DDE
I--KAIPVK----NRYLTFITKTGMVKKTELSQYK----KPLVALNLK-DTL-V----H--EHDLFLVTHLGYGL------V--VGPRAAGVKGINLK--
-DVVSGKIMERKAFLVIATHRGAVKKMSL-------RAKRGLVML----RLPHRA-GAEIVK---NFYLETEKGMIESVDV-SLRP---YSNGSFVIDEQ
A--VIRVWIEN-
>tr|A0A084GS99|A0A084GS99_9BACI DNA topoisomerase 4 subunit A OS=Bacillus indicus LMG 22858 GN=parC PE=3 SV=1
LEVMIPSEDVIVTVTKDGYIKRTSSRSYSASN--G---------TD-RLLGK-FDNTTETILLFTSKGNYIYCPVHEIPD-----LGQHIANLVSL-EDE
Q--KAMPVK----AQYLLFVTKNGMVKKTELKLYK----KALMAVNLK-DEL-V----F--NDDLFLATQFGYGL------V--VGARAAGVKGMNLK--
-DVAGAAVFPAIPQVVIVTQRGAAKKMSL-------RAKRGLIML----RLPHRV-GMHLVD---KLMLKTEKGHTEEVHA-QLRA---YSNGSFFIDEG
S--VKEVWVPV-
>tr|A0A0Q6L9U1|A0A0Q6L9U1_9BACI DNA gyrase subunit A OS=Bacillus sp. Leaf406 GN=ASG66_10445 PE=4 SV=1
LEVLIASEDVMVTVTSDGYIKRTSLRSYSASN--G---------TD-RLLGQ-YENTTDVLLVFTNKGNYVYCPVHELPD-----LGQHIGNIVPI-DDE
Q--KAVPVK----SLYLMFITKNGMVKKTEMLQYK----RPLVAINLK-DEL-V----H--THDLFLATNSSYGL------V--VGPRAAGVKGINLK--
-DVVSGKIIT-KQAVVLATHRGAIKKMKLS------RAKRGVIML----RLPHRS-GAEIVS---TVTLLTSKGKLETVQV-SIRF---YSNGSFVIDEG
S--VTKLWAVP-
>tr|A0A0J1LG40|A0A0J1LG40_BACCI DNA topoisomerase 4 subunit A OS=Bacillus circulans GN=parC PE=3 SV=1
LEVLIASEDVIVTVTKDGYIKRTSQRSYAASN--G---------TD-RILAK-IDNTTEVLLLFTDKGNYLYLPVHELPD-----LGQHISNIIPI-DDE
S--KAMPIK----TQYLLFFTKNGMAKKTELINYK----KPLVAINLK-DEV-V----F--KQEVLIATHIGYAL------I--VGARAAGVKGINLK--
-DVVAGKVIT-QESVVIITQRGSIKKMKLT------RAKRGLIML----RLPHRV-GMTIAG---TIYIQTEKGEIESVKT-DLRF---YSNGSFIIDET
A--IVELWEEK-
>tr|A0A0N8GH18|A0A0N8GH18_9BACI DNA gyrase subunit A OS=Bacillus vietnamensis GN=AM506_08290 PE=4 SV=1
LEVLIASEDVMVTVTRDGYMKRTSLRSYSASN--G---------TD-RLLGQ-YENTTDVLLVFTNKGNYIYCPVHELPD-----LGQHVGNIVPI-DDE
Q--KAIPIK----AHYLLFVTKNGMIKRSELPQYK----RPLVGINLK-DEL-V----H--SNDVFIATHLSYGL------V--VGPRAAGVKGVNLK--
-DVVSGKMIR-KDFIFLATQRGAVKKMKLA------RAKRGVIML----RLPHRV-SIEVVK---KVGLLTTKGKAEEVNV-DFRP---YSNGSFVIDEG
S--VCETWAES-
>tr|W1SBG0|W1SBG0_9BACI DNA topoisomerase 4 subunit A OS=Bacillus vireti LMG 21834 GN=parC PE=3 SV=1
LEVTVPSEDVIVTVTKHGYIKRTSGRSYAASN--G---------SD-RLLAQ-LDNTQDVLLLFTNKGNYLFCPVHELPD-----LGQHVANIIPI-EDE
E--QAIPVK----EAYLVFVTKNGMVKKTELKAYK----KPLVGINLK-DQV-I----H--TKEVFLITYFGYSL------I--VGVRAAGVKGINLK--
-DVVGGKILT-NETIVIATQRGAVKRMKLK------RAKRGVVIL----RLPHRM-GFVVAN---VVFIQTDKGHLETLKT-EIHF---YSNGSFILDEG
N--VTTLWKVA-
>tr|W4RP09|W4RP09_9BACI DNA topoisomerase 4 subunit A OS=Bacillus boroniphilus JCM 21738 GN=parC PE=3 SV=1
LEVLIASEDVIVTVTKDGYVKRTSQRSYAASN--G---------TD-RLLSQ-LNNTKDVLLLFTNKGSYLYLPVHELPD-----LGQHVANLVPL-DDE
D--KAVPVT----NLYFVFVTKNGMVKKSELNLYK----KPLTAINVK-DRV-I----H--EKDLFLSSHFGYGL------I--IGIRAAGVKGMNLK--
-DVVGGKIID-NHSIVIATQRGAIKKMKLS------RAKRGVVML----RLPHRI-GVEAVR---EVFFQSEKQQIVSVKA-ELRF---YTNGSFLVDES
T--LTAIWKSE-
>tr|A0A0Q3TK99|A0A0Q3TK99_9BACI DNA gyrase subunit A OS=Bacillus shackletonii GN=AN964_11015 PE=4 SV=1
LEVMIPNEDVMVTVTKDGYVKRTSIRSYTASN--G---------TD-RLLFQ-EENTTNVILLFTNKGNYLYCPVHELPD-----LGQHIANIVPI-EDE
Q--KVITIQ----PQFLLFVTKNGMVKKTELSQYN----KPLVAINLK-DEV-V----H--QKDLFIATHIGYGL------V--VGARAAGVKGINLK--
-DVVSGKIIL-KEFIFIATQRGAIKKMKIA------RAKRGVVML----RLPHRA-GMDIVD---IMNVQTEQNNIEQINI-EMRA---YSNGSFIFDES
N--TVGIWKDT-
>tr|A0A0Q3VH86|A0A0Q3VH86_9BACI DNA gyrase subunit A OS=Bacillus sp. FJAT-18043 GN=AN957_13225 PE=4 SV=1
LEVLVASEDVIVTVTKEGYVKRTSQRSFAASN--G---------SD-RLLAQ-LENTTDVLLVFTNKGNYLYCPVHTLPD-----LGQHIANIIPI-DDE
T--KALPIK----SSFLLFVTKNGMAKKTELKDYK----KPLVAINVK-DEV-I----Y--TKELFLSTYNGYGL------V--VGTRAAGVKGINLK--
-DVTGGQLID-NQAVVIVTQRGSIKKMKLT------RAKRGVVML----RLPHRI-GSVIVS---DVFIETDKGHIESTKA-NIRF---YSNGSFMIDES
F--VTDVWKVT-
>tr|G9X1G9|G9X1G9_9FIRM DNA gyrase subunit A OS=Peptostreptococcaceae bacterium ACC19a GN=gyrA PE=3 SV=1
IKDTIPNEDVTITLTHQGYIKRLPVDTYKAQKRGGKGIASMTT-EEDFVEKLIITSNHEKLLFITTLGKIYTLNAYEVPQS-RTAKGTNVINLLPLEKGE
SITSIITTK-D--NNYLVMCTKKGVIKKTKVSEFTKSKRQGLIAISLDEGDELVNSLLTQDNSQFIIITKKGMAIMFE---IRPMGRQARGVRGIKLK--
-EVVSVEIASQDKQLLIISENGYGKRTDINKYK-QSRGGVGLKTYKITE-KTGNIADAKVVD-KDEVMIINSDGTLIRTEVSEIS-LSRDTSGVRVMRST
--IISAIEIIA-
>tr|E0QM61|E0QM61_9FIRM DNA gyrase subunit A OS=[Eubacterium] yurii subsp. margaretiae ATCC 43715 GN=gyrA PE=3 SV=1
IKDTIPNEEVTITLTHQGYIKRLPVDTYKAQKRGGKGISSMTT-EEDFVEKLLITSNHEKILFITNKGKIYNLNAYEIPQS-RTAKGSNIINLLPLEKDE
KIATIITTR-N--NAYIVMCTKKGIIKKTRISEFTKSKRQGMKAINLKEDDELVNSLLTADNTNLFLVTKKGMAIMFE---LRPMGRTATGVIAMRLK--
-EIVSLEIASNDKQVLIISENGYGKRTQVSKYK-QSRAGVGVKTYKITE-KTGNIADAKIVE-SDEVMIINSDGTLIRTPVAEIS-LSRDTSGVKVMRSG
--IISAIEIIQ-
>tr|A0A0G0ZLD0|A0A0G0ZLD0_9BACT DNA gyrase subunit A OS=Parcubacteria (Azambacteria) bacterium GW2011_GWF2_42_22 GN=gyrA PE=3 SV=1
EEDLMPLEDAVIVLTDSGYVKRMNPTVVKAQHRGG-G--TVS--ED-AVTHFISCETHDNALFFTSAGRVFQTKVWEIPES-RQSRGKAAVNFL-ASD-E
Q--AVLTYN--GVEKYFVMATQNGLIKKTPIADFSS-R-SGLIAIKIK--DALQW---SD---QIIMVTSQGQAI------SRSMGRATAGVMGIRLHK-
-DVVGMDVISSGAKILVVMENGFGKKTLL-FYK-QNRGGSGVKTA---TPKTGAV-AAFAVQ-AEEIIAISKKGTVIRVSL-SIST-SR---GVRIMRVE
P-HVVSATLL--
>tr|A0A0G0XNP8|A0A0G0XNP8_9BACT DNA gyrase subunit A OS=Parcubacteria (Yanofskybacteria) bacterium GW2011_GWC2_41_9 GN=gyrA PE=3 SV=1
EEDLVPLEEAVVVLTESGYVKRMNPALVRAQHRGG-G--TMG--ED-AVTHFVSTQTHDNALFFTNIGRVFQTKVWEIPES-RQSRGKAIVNFL-ASD-E
K--AILTYN--SGEKYFVMATKNGLVKKTPIADFGS-R-SGLIAIKLK--DSLKW---SD---QIIFVTSQGQAI------ARPLGRATAGMHGIRLHA-
-GVIAMDIISANTKFLVIMENGFGKKTFI-LYK-QNRAGSGVKTA---TPKTGKV-SAFVLT-VKEMIAISKKGVVIRTDI-SIST-SR---GVRIMRVE
P-KVVSATLL--
>tr|A0A0G0ISU9|A0A0G0ISU9_9BACT DNA gyrase subunit A OS=Parcubacteria (OD1-vii) bacterium GW2011_GWA2_38_13b GN=gyrA PE=3 SV=1
VEDLIPNEEAILVLTRSGYIKRVNPNIYRTQKRGG-G--IMM--ED-QVESMLGVETHDDILFFTDSGKVFKVKAYEIPES-RVSKGQAIMNFL-QNK-E
H--SIISLG--KENKFLVMATKYGIIKKTNISEFAN-R-VGLVAIKLQ--DSLKW---TD---EVILVTSKGQAI------VRSMGRGASGVRGIRLKK-
-DMVGMDIIKK-VDLLIVTENGFGKKTPV-YYK-QKRGGSGIKTA---TSKNGGI-AATTIA-ASDIVTISSQGKVIRTPL-SISV-GR---GVRIMRLD
--KAVSITCL--
>tr|A0A0G1QSK6|A0A0G1QSK6_9BACT DNA gyrase subunit A OS=Parcubacteria (Azambacteria) bacterium GW2011_GWC1_46_13 GN=gyrA PE=3 SV=1
EEDLIPQEETVIILTHGGYVKRLKPSAYRMQKRGG-G--IIT--ED-AVEHFLSGYTHDNVLFFTTQGRVFQSHVYEIPET-RQARGKAVVNFL-NGH-E
T--AVVTYG--NIFKHLVMATKNGIIKKTPVEDFAS-R-SGLIAIKLK--DILKW---S---DEVVLITSLGQAI------IRPMGRNAAGVTGMRIKG-
-ELVGMDIVAKKGYLLIITENGFGKRTAL-AYR-QRRGGSGIKTA---TSKTGRV-SARIVS-EKELIAISQKGQVLRTDF-NIKI-GR---GVTIMRLE
G-KVATITCL--
>tr|R6U4Z4|R6U4Z4_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:465 GN=gyrA PE=3 SV=1
IESLIKEETNVVTLTHFGYIKRIAADTYRSQKRGGKGLTAMNT-EDDFVEHLFVTSTHDYIMFFTTTGRVFRLKAYEIPEG-RTAKGMAIVNLLQLGQ-E
KIAAVIPVH---DELFVLMATRNGLIKKTKLSEYSN-RKTGIQGITLKEDDELIDVR-TDG-TSIIMVTRQGMSIRFKE--VRAVGRISMGVKGINLS--
-DVVGMEPIKN-DYILAITENGFGKRTEVEEYREQARAGKGILTYKTT-A-TGHIIGVQIVNK-DDVMLITDTGVVIRINVKDISVLGRNTQGVTLMRTS
GG-VVNIAKIL-
>tr|R5STS5|R5STS5_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:1219 GN=gyrA PE=3 SV=1
VESLIKEETNVVTLTHAGYIKRIAADVYKSQRRGGKGLTAMST-EEDFVEHLFVTSTHNYIMFFTNQGRAFRLKAYELPES-RTAKGTAIVNLLQLSQ-E
KIAAVMPIE---ADKYVLMATRNGLIKKTKLEEYSN-RKSGIQGITLKENDELIDAR-TDG-SDIVMVTREGLSIRFDE--VRPMGRTSMGVKGITLS--
-DVVGMEPVTS-DYVLAITENGFGKRTEVDEYRTQSRSGKGILTYKTT-Q-TGHIIGIKIVNT-DDIMMITDTGVIIRINVKDVSVLGRNTQGVTLMRTS
GG-VINIAKLP-
>tr|Q83VM8|Q83VM8_STRSU DNA gyrase subunit A OS=Streptococcus suis GN=gyrA PE=3 SV=1
DEDLIEEADVLITLSNQGYIKRLAQDEFQAQKRGGRGVQGTGV-DDDFVRELVSTSTHDHLLFFTNKGRVYRLKGYEIPEYGRTAKGLPVVNLLKL-ENE
SIQTIINVT--A-DHYLFFATRQGIVKRTNVNEFSN-RQNGLKALNLKDDDELINVF-TDG-ADVIMGTKFGYSVRFAE--VRNMGRTATGVRGIKLR--
-GLVGATIVSDDQEVLVLSENGYGKRTPASEYPTKGRGGKGIITLKVA-D-NGPLAGLTTVQD-EDIMVITDTGVIIRTSIANISQTGRSTMGVKVMRLD
E-KIMTFALVD-
>tr|E8UAE8|E8UAE8_DEIML DNA gyrase subunit A OS=Deinococcus maricopensis (strain DSM 21211 / LMG 22137 / NRRL B-23946 / LB-34) GN=gyrA PE=3 SV=1
KEDLIAVEDMVITMTRAGYLKRTKLDAYRAQSRGGRGSSGGKL-EEDVNTRVFVGSTHDYLLFFTDQGRLFHEKIYDLPEAGRDAKGTHIKNLLPGR-NE
SVASVLAIK---EAGSFVFATKRGMIKKTQIRDYGNITSAGLIALNLQDDDGLIGVG-QRDGDHIVLATSDGQAMRFGA--VRDTGRATQGVIGIRLR--
-HVVSMAVVPGDSELLAISECGLGKRTPVSDYPSKGRGGLGVITL--TK--TGKLVALARVAGDEELMVLTQKGTVIRTRVEEVRVTGRNAQGVKIINLG
-GCVISAFPIR-
>tr|F0RM54|F0RM54_DEIPM DNA gyrase subunit A OS=Deinococcus proteolyticus (strain ATCC 35074 / DSM 20540 / JCM 6276 / NBRC 101906 / NCIMB 13154 / VKM A
KEDLIAVEDMVITMTEAGYLKRTTLDAYRAQSRGGRGSRGGKL-EEDVNTRVFVGSTHDYMLFFTDQGRLFHEKIYDLPEAARDAKGSHIRNLLPSR-DE
NIASVQSIR---EEGSFVFATKNGMVKRTLITDYGNITSAGLIAINLQEDDELISVG-VKNGSDIVLATRGGKAMRFAA--VRDTGRATQGVIGIRLK--
-RVVSMALVPAESELLAISEHGLGKRTPVSDYPSKGRGGQGVITL--TK--TGRLVTLARVDGGEELMVLTQGGLVIRTRVEEVRVTGRNAQGVKVINLS
-KRVISAFPIR-
>tr|A0A0F4LSS9|A0A0F4LSS9_9LACO DNA topoisomerase 4 subunit A OS=Lactobacillus apis GN=gyrA1 PE=3 SV=1
EKALVADEQVRVLISKDGYLKRSSLRSWQSSD--D---------GD-EVVFE-KTSTLTCLYLFTNHGNVIFRPVNELIE-----TGQHLSQEI-G-NDE
Q--RVFDFE---QKVNFLIATDDGYIKQLQLANLQ----RAITAIKMK-DSKVVR---Q--KQEIILFTHNAYAV------I--SGAKAVGVKSVNLK--
-DVVSYVLIQPLMRVGLITQRGAFKQFKAN------RAKRGVLVL----RLPHRV-AVASYG-DHTLMITTSSKRHIKVNT-EFPL---YSNGSFVIDTT
E--PVSLRIGN-
>tr|A0A089Y0X7|A0A089Y0X7_9LACO DNA topoisomerase 4 subunit A OS=Lactobacillus sp. wkB8 GN=parC PE=3 SV=1
EKALVADEQVRVLISRDGYLKRSSLRSWQSSD--D---------GD-DVVFE-KTSTLTNLYLFTSRGNVIYRPVSELVE-----TGQHLSQEI-G-DDE
N--RVFDFA---QNINFLLATNDGYIKQLSLSNLQ----RAITAMKMK-DSKVIR---K--AAEIILFTHNAYAI------V--SGAKSFGVKSVNLK--
-DVVSYVLVNPLLRIGLITQRGAFKQFKAD------RAKRGVLVL----RLPHRA-AVTAYG-DHTLFVTTTSKRKIKVLT-EYPV---YSNGSFVIDIT
D--PVNIRLGK-
>tr|A0A0F4LE12|A0A0F4LE12_9LACO DNA topoisomerase 4 subunit A OS=Lactobacillus melliventris GN=parC PE=3 SV=1
EKALVADEQVRVLISRDGYLKRSSIRSWQSSD--D---------GD-DVVFE-KTSTLTNLYLFTSRGNVIYRPVNELVE-----TGQHLSQEI-G-NDE
N--RVFDFD---QNVNFLLATNDGYIKQLQLSNLQ----RAITALKMK-DSRVVR---K--NDEIILFTHNAYAI------I--SGAKSFGVKSVNLK--
-DVISYILINPLVHVGIITQRGAFKQFKAD------RAKRGVLVL----RLPHRV-AVTSYG-DHTLIVTTKSKRHIKILT-AYPL---YSNGSFVIDTT
D--PVNIKLSR-
>tr|A0A0F4LCM9|A0A0F4LCM9_9LACO DNA topoisomerase 4 subunit A OS=Lactobacillus kullabergensis GN=gyrA1 PE=3 SV=1
EKALVADEQVRVLISRDGYLKRSSIRSWQSSD--D---------GD-DVVFE-KTSTLTNLYLFTDRGNVIFRPVNELVE-----TGQHLSQEI-G-SNE
N--RVFDFE---QKLNFLMATNDGYIKQLELSNLQ----RAITAMKMK-DSKVVR---K--NKEIILFTHKAYAV------I--SGAKSFGVKSVNLK--
-DVVSYIVINPLIRIGIITQRGAFKQFRAG------RAKRGVLVL----RLPHRA-AVTSYG-DHTLLITTTSRRHIKIST-DYPL---YSNGSFVLDTT
D--PVNIKLGR-
>tr|V9G5U4|V9G5U4_9BACL DNA topoisomerase (ATP-hydrolyzing) OS=Paenibacillus sp. JCM 10914 GN=JCM10914_1337 PE=4 SV=1
LEVLVNAEDVVVTLSNDGYIKRTSMMSFTRSG--GE--------GD-YITRL-FQNTLENLLIFTSRGQYFLLPVHQIPE-----AGTAIVNVIQV-PED
Q--SVIPVS---SDKSLVFVTRKGQVKRTELKEYI----GAVAAAKIA-DSV-V----V--TQEILLVSKDGMSI------V--MGRVSGGVRGIQLR--
-DVVAALW-VEEGEILTITDLGYGKRSLLL------RGGKGMATF--KGKVGSAV-GAFYCK---QIVAYSNEGTAYPIAT-QVTI---KSIGKLLADVA
R--SFIW-----
>tr|W7Z6E2|W7Z6E2_9BACL DNA topoisomerase 4 subunit A OS=Paenibacillus pini JCM 16418 GN=parC PE=3 SV=1
LEVLVNAEDVLVTMSRDGYIKRTSMLSYTRSG--GE--------GD-YISRV-LNNTLDNLLIFTEKGQYYLLPVHQIPE-----PGTAIVNVIHL-PED
Q--ALIPVT---PGRSLVFVTKRGQVKRTELKEYM----NAVSACKVG-DEI-I----T--SKDILLVSKEAMSI------V--MGRVSSGVRGIQLR--
-DIVSALW-VEEGEILAITDQGYAKRSLLL------RGGKGLVTF--KGKVGSRA-GAFYCR---EITAMTKDGQSYNFTS-QAPL---KATGKWLVHLE
K--IIDLVIR--
>tr|R9LE42|R9LE42_9BACL DNA topoisomerase 4 subunit A OS=Paenibacillus barengoltzii G22 GN=parC PE=3 SV=1
LEVLVAQEDVLVTISHEGYIKRTSMLSFTRSG--GE--------GD-YMKYL-LEDTLQNLLIFTQRGQYFLLPVHQIPE-----NGTAIVNVIPL-AED
R--SVIPVK--NPELSLVFVTKNGQVKRTELKEYE----GAVAACKVG-DEV-L----T--NQEILLLTKQGMAI------V--MGRVSAGVRGINLK--
-DVVAALW-VEEGEVLVVSDLAYAKRSLLL------RGGKGVQTF--KGKVGSRV-GGIHCK---LLQAVTKEGQMHTFSS-DAPI---KSIGKAMMSVD
N--IVDLFVKE-
>tr|A0A090YB66|A0A090YB66_PAEMA DNA topoisomerase 4 subunit A OS=Paenibacillus macerans GN=parC PE=3 SV=1
LEVLVAQEDVLVTLSNEGYIKRTSMLSFTRSG--GE--------GD-YIKHL-FEDTLQNLLIFTQRGQYFLLPVHQIPE-----NGTALVNVIPL-AED
R--SVVPLR--DAELSLVFVTKRGQVKRTELKDYE----GAVAACKLG-DEV-L----T--RQEIVLLTKQGMAI------V--MGRVAAGVRGINLK--
-DVVAALW-VEEGEILVVSDLGYGKRSLLL------RGGKGVQTF--KGKVGSRV-GGIHCK---TLTAVTKEGQMHNFSS-DAPL---KSIGKALAPID
N--IVDFFIKE-
>tr|A0A089LF51|A0A089LF51_9BACL DNA topoisomerase (ATP-hydrolyzing) OS=Paenibacillus borealis GN=PBOR_22875 PE=4 SV=1
MEVLVNAEDVLVALSADGYIKRTGMPSFTRSG--GE--------GD-HIVKL-LDNTRDSLLVFTRKGQYFLLPVHQIPE-----PGTAIVNVIGL-AGD
G--SVLPVG---PLASLVFVTRKGQVKRTELKEYS----GAVAACKVA-DEI-I----A--DKDIVLVTREGMSI------V--MGRVATGVRGIQLR--
-DVVASFW-VGEGEILAVTEIGYAKRSLLV------RGGKGMPTF--KGKVGSRA-GAFYCK---ELTAITQSGAVHTFSS-AAPL---RSIGKQLVAVE
K--IISLYPAV-
>tr|E0I4X1|E0I4X1_9BACL DNA topoisomerase (ATP-hydrolyzing) OS=Paenibacillus curdlanolyticus YK9 GN=PaecuDRAFT_0693 PE=4 SV=1
LEVMVQSEDVLLTVSREGYIKRTTMLSYTRSG--GE--------GD-VVRHL-LSNTIDSLLLFTKKGQYFVLPVHQVPE-----NGTALVNVIPL-SED
S--GIVPIR---ASASLLFITKRGQVKRTELKEYK----TAIAACKVG-DEV-I----L--NQELLLVSRQGMAI------V--MGRVAAGVRGMQLK--
-DIVGCAL-VAEGEVLVLSDLGYGKRSLLA------RGGKGIATF--KGKVGNGT-GAVYCK---SLILIAASGATWTLPT-KTPI---RSIGKPLVTLD
N--ITECFTRL-
>tr|V9W857|V9W857_9BACL DNA topoisomerase 4 subunit A OS=Paenibacillus larvae subsp. larvae DSM 25430 GN=parC PE=3 SV=1
LEVMVTPENVLVTLSQDGYIKRVSILSYTRSG--GE--------GD-FVRHL-LESTIDSLLIFTNRGQYFLLPVHQIPE-----NGTAIVNVIPM-SED
R--NVIPVK---SGKSLVFVTKKGQVKRTELKEYM----TAVVACKVG-DEV-I----E--NKDLLLVTKQGMSI------V--MGRAAGGVRGIQLK--
-DVISAEW-IFEGELLVISDRGYAKRTLVF------RGGKGILTF--KGKVGTEI-ASFLVK---DITAYLNNGEQVIFST-KAPL---KATGKVVIPVG
T--ITHIQRMP-
>tr|A0A0F5QZC7|A0A0F5QZC7_9BACL DNA topoisomerase (ATP-hydrolyzing) OS=Paenibacillus sp. D9 GN=VE23_03145 PE=4 SV=1
LEVLVSAEDVLVAISREGYVKRTGMLSFTRSG--GE--------GD-SIRYL-LESTIDSLLVFTRKGSYYMLPVHAIPE-----AGTAIVNVIPI-PDD
G--AVIPVK---PGESLFFFTRKGQVKRTELKEYA----TAVAACKVA-DEI-V----M--ASHLLLVSKLGSAI------V--MGRVSGGVRGMQFK--
-DLAAALEVSREGEILVISDLGYGKRSLLA------RGGKGVQSF--KGKVGSRA-GAWYCR---ELNVQLSSGSVQRFLT-KTPI---RSIGRQLAQVE
N--VQQLYARP-
>tr|A0A069DCS2|A0A069DCS2_9BACL DNA topoisomerase (ATP-hydrolyzing) OS=Paenibacillus sp. TCA20 GN=TCA2_2571 PE=4 SV=1
LEVLVNSEDVLVTLSNEGYIKRTSKLSFTRSG--GD--------GD-VISSY-YDNTLDNLLVFTQRGQYYLLPVHQVPE-----PGTAIVNVIPL-SED
R--TIIPVR---EEASLVFVTRRGQIKRTALKDYV----SAVAACKVG-DEV-I----H--GRHILLVSKLGQSV------V--MGRVSGGVKGIQLK--
-DLVTAVW-VDEGEIFTITDLGYGKRSLLL------RGGKGVATF--KGKVGSQV-AAYHVK---RLLALTDQGKMLGFST-SAPI---RSTGKALVSVE
N--IVQIIDNR-
>tr|A0A0M0W4M2|A0A0M0W4M2_9BACI DNA topoisomerase 4 subunit A OS=Bacillus sp. FJAT-18019 GN=parC PE=3 SV=1
LEVLVNAEDVIVTLSNEGYIKRTSMLSFTRSG--GE--------GD-YITRL-FENTLENLLIFTNRGQYFLLPVHQIPE-----AGTAIVNVIQV-PED
H--SVIPVS---PGKSLVFVSRKGQVKRTELKDYV----GAVAAAKVA-DSI-I----V--NKDIVLISKDGMSI------V--MGRVSGGVRGIQLR--
-DVVAALW-VEEGEILTITDLGYGKRSLLL------RGGKGMATF--KGKVGSAA-GAFYCR---QITAYSGDGQAYQIHT-KVPI---KSIGKLLADVG
N--IVDLVSLP-
>tr|G4HFH7|G4HFH7_9BACL DNA topoisomerase 4 subunit A OS=Paenibacillus lactis 154 GN=parC PE=3 SV=1
LEVLVNAEDVLVTMSHDGYIKRTSMLSFTRSG--GE--------GD-HITRL-FENTLDNLLLFTSRGQYFLLPVHQIPE-----AGTAIVNVIQL-PED
S--SVIPVT---PGKSLVFVTRKGQVKRTELKDYV----GAVAAAKVA-DSV-I----V--TKDIVLISKDGMSI------V--MGRVSGGVRGIQLR--
-DVVSALW-VEEGEILTITDLGYGKRSLLI------RGGKGIATF--KGKVGSAA-GAFYCR---DITAYADDGQAYPIHS-KVPI---KSTGKLLADVG
K--IVSLVHLP-
>tr|E3H638|E3H638_ILYPC DNA gyrase subunit A OS=Ilyobacter polytropus (strain DSM 2926 / CuHBu1) GN=gyrA PE=3 SV=1
IEDLIKDEKVIVTLTNKGYVKRMNLDKYKAQKRGGKGVSTQNT-EGDFLENMYTASNLDTLMIFTDTGKVYNLKVYEIPES-KQSRGKLIANLINLQENE
KVKSIIKTR-F--TQDLLFVTKEGLVKKTVLSEFKNLNRSGLRAIKLKDGDDLIFVGLVES-DQVFIATKNGYSIKFP---ARNMGRATIGVRGINLR--
-DVVSAVIIKRDTTILTVTENGYGKRTREDEYPLQSRSGKGVINLRCNE-KTGVVVEVTSVT-EEELMAITSNGIVIRTPADTISL-GRATQGVRIMRVE
-DKLVSIVKVM-
>tr|A0A0E1RCD7|A0A0E1RCD7_LISMN DNA topoisomerase 4 subunit A OS=Listeria monocytogenes serotype 4b str. LL195 GN=parC PE=3 SV=1
TEVLVANEDVIVSVTKEGYVKRTSQRSYAASN--G---------AD-HAVFI-QKNSLDSLLLFTSKGNFIYRPVHELPD-----LGDHVSHLASDLSGE
E--SAIAIQ---E-KRFLFVTKNGMTKQSAITNYK----KSMMAIKLK-DEL-L----H--TEDIFLATKNGYGL------I--SGARTAGVKAINLK--
-DVIGGIVLMPK-HILLATQRGSLKQMKAS------RAKRGLLML----RLPHRI-GITLAD---HLFIETNTDQIVEIDV-NLRI---YSNGSFVLDET
E--PTSIWLAI-
>tr|W7BZ27|W7BZ27_9LIST DNA topoisomerase 4 subunit A OS=Listeria cornellensis FSL F6-969 GN=parC PE=3 SV=1
TEVLVASEDVVVSVTKEGYVKRTGMRSYAASN--G---------TD-HAIFI-QTNTMDSLLLFTSKGNYIYRPVHELPD-----LGEHVSHLVSDTSEE
E--AAIPMK---T-DYFLFVTKNGMIKASAVLNYK----KTLMAINLK-DSL-I----E--NEDVFLASHNGYGL------V--SGARTAGVKAMNLK--
-DIVGANVIVPR-DLILLTQRGSAKRMKLS------RAKRGLLML----RLPHRI-SLDLAG---IIHIATDKEVVVNLDV-NLRV---YSNGSFIMDEQ
E--PVETWLGL-
>tr|A0A099W7G5|A0A099W7G5_9LIST DNA topoisomerase 4 subunit A OS=Listeria booriae GN=parC PE=3 SV=1
TEVLVASEEVVVSVTKEGYVKRTGMRSYAASN--G---------TD-HAIFV-QSNTMDALLLFTSKGNYIYRPVHELPD-----LGEHISHLVTDASDE
D--AAIPMK---T-DNFLFTTKNGMIKASAVLNYQ----KTLMAINLK-DTL-L----S--TEDVFLASHNGYGL------V--SGARTAGVKAMNLK--
-DVAGAVVIAPK-DLVLITQRGSAKRMKLS------RAKRGLLML----RLPHRI-SLDLAD---IIHIATNKEVVVDLNV-NLRV---YSNGSFIMDEQ
E--PVETWLSL-
>tr|I3E850|I3E850_BACMT DNA topoisomerase 4 subunit A OS=Bacillus methanolicus MGA3 GN=parC PE=3 SV=1
LDVLVANEDVIVTVTKEGYVKRTSQRSYAASN--G---------SD-RLLAQ-FYNTTDVLLMFTNKGNYLYCPVHELPD-----LGQHIANLIQI-DDE
E--RAIPIK----DSYLLFITKNGMVKKTELKHYK----RPLVAINLK-DNV-I----H--NKEIFLATHFGYAV------V--VGARAAGVKGINLK--
-DVAAGKIIE-EEAVVIATQRGAIKKMKLT------RAKRGVVML----RLPHRI-GAEVVT---NVIVQTEKGHLENINI-TLRD---YSNGSFLFDVT
T--AKVLWKPK-
>tr|A0A0K9H4P5|A0A0K9H4P5_9BACI DNA topoisomerase 4 subunit A OS=Bacillus sp. FJAT-27231 GN=parC PE=3 SV=1
LEVLIPNEEVVVTVTKDGYIKRTSLRSYSASG--G---------TD-RLLYK-EEHTTDVLLVFTSKGSYLYLPVHELPD-----LGQHLASLVTL-EDE
S--TAFAIK----PLYLLFATKNGMIKRTELASYK----RALTAIKLK-DEV-I----H--NKQIFLATHFGYGL------V--VGPRAAGVKGINLK--
-DLVSMEVWE-EKDLLLVTHRGAVKKMKST------RAARGVVML----RLPHRA-GLAVID---QFVLQTAKGSTEQFDF-DLKR---YSNGTFVLDEN
S--VTSIWKQI-
>tr|A0A0C2UBF2|A0A0C2UBF2_BACBA DNA topoisomerase 4 subunit A OS=Bacillus badius GN=parC PE=3 SV=1
LEVLIPNEEVIVTVTKDGYIKRTSLRSYSASG--G---------TD-RLLFK-EEHTTDVLLVFTSKGSYLYLPVHELPD-----LGQHVASLVAL-EDE
S--SVFTVK----PLYLLFVTKNGMVKRTELAAYK----RPLTAIKLK-DEV-I----H--SKQVFLATYFGYGL------A--VGPRAAGVKGINLK--
-DVVSAEVWE-ERDLLLVTQRGAVKKMSSR------RASRGVVML----RLPHRA-GLKLIE---QFVLQTEKGLSDPFDF-ALKK---YSNGSFVLDEN
S--VIAVWKKI-
>tr|A0A077J5N8|A0A077J5N8_9BACI DNA topoisomerase 4 subunit A OS=Bacillus sp. X1(2014) GN=parC PE=3 SV=1
LEVMVASEDVIVTVTKDGYVKRTSLRSYAASN--G---------TD-RLLAM-LENTKDVLLLFTNKGNYLYCPVHELPD-----LGQHIANIIPI-DDE
E--KAIPIN----NGYFLFVTRNGMVKKTELKHYK----KPLTGINLK-DQV-V----H--MNELFLVTHNGYAL------V--VGVRAAGVKGMNLK--
-DIVSGQLIT-DESIVVATQRGAVKKMKLT------RAKRGVVIL----RLPHRS-GFVVAQ---TIYLQTEKSFIETIKV-DIRF---YSNGSFVLDEE
N--VISVWKVE-
>tr|A0A098F182|A0A098F182_9BACI DNA topoisomerase 4 subunit A OS=Bacillus sp. B-jedd GN=parC PE=3 SV=1
LEVMVPSEDVIVTVTKEGYIKRTSLRSFSASN--G---------SD-RLFAQ-LDNTKDVLILFTSKGNYLYLPVHELPD-----MGQHVANIIPI-EDE
E--KALPIQ----ESYLVFITKNGMVKKTELKLYQ----KPLTAINLK-DTL-I----H--QQDVFLVSNFGYAL------I--IGVRAAGVKGMNLK--
-DVAGGKVLS-KESIIVVTQRGAIKKMRLK------RAKRGVVVL----RLPHRA-GIEAAL---LLFILTEKGEVVEVNT-SLKY---YSNGSFIIDEG
S--VTSLWKKT-
>tr|K6DBR5|K6DBR5_9BACI DNA topoisomerase 4 subunit A OS=Bacillus bataviensis LMG 21833 GN=parC PE=3 SV=1
LEVTVPSEDVIVTITKHGYVKRTSQRSFAASG--G---------SD-RLLDQ-LDNTKDVLLLFTNKGNYLFCPVHELPD-----LGQHVANIIPI-EDE
E--KAVPVK----DAFFVFVTKNGMVKKTELKAYK----KPLVAVNLK-DQV-I----H--TKEIFLITNQGYAL------I--VGIRAAGVKGINLK--
-DVVGGKLIT-KESIVIATQRGSVKRMKLK------RAKRGVVIL----RLPHRM-GFVIAN---TIYIQTEKGFIETLKV-DIRF---YSNGSFILDEG
N--VNTVWKVE-
>tr|E5WND8|E5WND8_9BACI DNA topoisomerase 4 subunit A OS=Bacillus sp. 2_A_57_CT2 GN=parC PE=3 SV=1
LEVLVASEDVIVTVTKEGYVKRTSQRSFAASN--G---------SD-RLIAK-LDNTTDVLLVFTNKGNYLYCPVHQLPD-----LGQHIANIIPI-DNE
S--RAIPVK----EEYLLFMTKNGMVKKTELKAYK----KPLVAVNVK-DEV-L----Y--TKEIFLATHQGFGL------V--VGARAAGVKGINLK--
-DVAGAQLIE-EQSVVIVTQRGSIKKMKLS------RAKRGVVML----RLPHRV-GCVIVR---ELYIETEKGHIEAVNV-SIRF---YSNGSFIIDES
S--AKCIWRAE-
>tr|A0A0M5JDV5|A0A0M5JDV5_9BACI DNA topoisomerase 4 subunit A OS=Bacillus sp. FJAT-18017 GN=parC PE=3 SV=1
LDVLIPSEDVIVTVTKEGYVKRTSLRSFTASN--G---------SD-RLFAQ-LDNTKDVLLLFTSKGNYLYIPVHVLPD-----MGQHVANLIPI-DDE
E--KAIPVN----NLYLLFVTKNGMVKKTEMKLYQ----KALTAINLK-DKL-I----H--TKELFLISHYGYAL------V--IGIRAAGVKGMNLK--
-DLVGGKLLD-KEYIVLATQRGALKKMKLK------RAKRGVVVL----RLPHRT-GFESTE---VINILTEKGQTFAINT-DLKF---YSNGSFIVDET
S--VTTLWKEA-
>tr|A0A0K1IG31|A0A0K1IG31_STRAG DNA gyrase subunit A OS=Streptococcus agalactiae GN=gyrA PE=3 SV=1
DEDLIEEEDVLITLSNKGYIKRLAQDEFRAQKRGGRGIQGTGV-NDDFVRELVSTSTHDTVLFFTNLGRVYRLKAYEIPEYGRTAKGLPIVNLLKL-DGE
TIQTIINAR--A-NKYFFFTTQQGIVKRTSVSEFSN-RQNGLRAINLKENDELINVL-IDE-EDVIIGTRTGYSVRFKV--VRNMGRTATGVRGVNLR--
-GVVGASRIVNGQEVLIITEKGYGKRTEASEYPTKGRGGKGIKTANIT-A-NGPLARLVTINN-EDIMVITDTGVIIRTNVANISQTGRSTMGVKVMRLD
E-KIVTVALVE-
>tr|A0A0R2MS06|A0A0R2MS06_LACHE Dna topoisomerase (Atp-hydrolyzing) parc OS=Lactobacillus helveticus GN=IV62_GL000688 PE=4 SV=1
EKALVADEQVRVLISRDGYLKRTSLRSYQSTD--D---------GD-KVIYE-NTSTLSNLYLFTNHGNVIYRPVHELVE-----TGQHLSQEI-G-DDE
Q--RVFVFD---INKNFILATNDGYIKQLELTNLQ----RAMTAIKLK-DSMLIG---N--KKEITLFTHRAYAV------I--SGSKAVGVKSVNLK--
-DIVGYVLVDSLMHVGLITQRGAFKQFKLS------RAKRGVLVL----RLPHRV-ALMPYA-DHILHVTTSSDRNIEIKT-EYPL---YSNGSFVIDTT
D--PKNIELGR-
>tr|G5KFV1|G5KFV1_9STRE DNA gyrase subunit A OS=Streptococcus urinalis 2285-97 GN=gyrA PE=3 SV=1
DEDLIEEEDVLITLSNKGYIKRLAQDEFRAQKRGGRGVQGTGV-DDDFVKELLSTNTHDHVYFMTNKGRVYRLKGYEIPEYGRSAKGLPIVNLLKL-DHE
TIQTIISEK--K-ENYFFFVTKHGVVKRTKESEFRN-RQNGLKALGLKEGDELINVF-TNG-DDIIIGTKLGYSVRFNE--VRSMSRSATGVRGVKLR--
-EVVSAARITDSQEVLVITENGYGKRTAATEYPTKGRGGKGIKTANIT-S-NGPLAGLLTVND-EDIMIITNTGVIIRTNVANISQTGRATLGVKVMRLD
E-KIMTFTLVD-
>tr|F6B3U8|F6B3U8_DESCC DNA gyrase subunit A OS=Desulfotomaculum carboxydivorans (strain DSM 14880 / VKM B-2319 / CO-1-SRB) GN=gyrA PE=3 SV=1
IEDLIDEEGMVVTITNQGYIKRISLDTYRSQRRGGKGITAMGT-EEDFVKHLFVASTHHYLLFFTNQGKAYRLKVHEVPEG-RTAKGTPLVNLLYISS-E
YVTTVIPIK---EEAYLFMATKQGVVKKTNLSEYDT-RRDGINAINLDESDELVAVE-THG-EEIILSTREGMAIRFPE--VRPMGRTARGVKGITLT--
-DVVNMDVVK--GDLLVVTANGYGKRTNLDEYRTQTRGGKGIINIKTS-P-NGPVVGALVVKD-DEIMMISAEGIMIRLAAKDVSTFGRNTQGVTLMKVA
ND-IVAVAKVA-
>tr|K8EI67|K8EI67_9FIRM DNA gyrase subunit A OS=Desulfotomaculum hydrothermale Lam5 = DSM 18033 GN=gyrA PE=3 SV=1
IEDLIDEEDMVVTLTNQGYIKRISLDTYRSQRRGGKGITAMGT-EEDFVRHLFIASTHHFLLFFTNKGKVYRLKVHEVPES-RTAKGTPIINLLNFDH-E
YVSTVIPIK---EDAFLFMATKNGTVKKTPLTEYNS-RRDGIIAITLDQEDKLVAVE-TYG-EEIILGTQEGTAIRFSE--VRPMGRAARGVKGITLS--
-NVVNMDVVK--ADLLTVTANGYGKRTPLSEYRSQSRGGKGIINIKTT-K-NGPVVGVQVVKE-DEIMMISAEGIIIRLPARDVSSMSRNTQGVTLMKTA
ND-IVAIARVV-
>tr|A0A0F2PVC9|A0A0F2PVC9_9FIRM DNA gyrase subunit A OS=Peptococcaceae bacterium BRH_c4b GN=gyrA PE=3 SV=1
VEDLIPEEDMVITITNQGYIKRISSDTYRSQKRGGRGINAMDT-AEDFVRHLFITSTHHYFLFFTNKGKVYRLKVHEIPEG-RTAKGTPLVNVLYIDQ-E
KVTAVIPVR---GNMFLFMATRQGVIKKTALKQYDT-RRDGIIAINLDPEDELVEVK-TDG-QEIMLGTRNGLAIHFSE--VSPYGRTARGVKGINLL--
-KVVSMDTIK--ADVLVVTVNGFGKRTPVAEYRLQTRGGKGIINIKTT-E-NGEVVSLQMVRD-EEVMMISAEGIIIRIRAGDVSLMSRVTQGVTLMRLD
GD-LVALAKVN-
>tr|F6DL06|F6DL06_DESRL DNA gyrase subunit A OS=Desulfotomaculum ruminis (strain ATCC 23193 / DSM 2154 / NCIB 8452 / DL) GN=gyrA PE=3 SV=1
IEDLIDEESMAVTITNQGYIKRISADTYRNQKRGGKGITAMGT-QEDFVKHLFVASTHHYLLFFTNKGKVYRLKVHEVPEG-RTAKGTPLVNLLYISG-E
YVTTVIPIK---DDTYLVMATRQGIIKKTPLTEYNT-RRDGIIAIHLEQEDELVAVE-TSG-EEIILSTKNGMAIRFSE--VRSMGRTARGVKGISLS--
-RVVNMDVVK--SDLLVVTANGFGKRTSLEEYRSQTRGGKGIINIKTT-S-NGLVVGVQVVED-DEIMIITAEGVIIRIFASDVPHYGRNTQGVTLMRTA
TD-IVAIARVV-
>tr|A4J0F6|A4J0F6_DESRM DNA gyrase subunit A OS=Desulfotomaculum reducens (strain MI-1) GN=gyrA PE=3 SV=1
IEDLIDEEDMVVTITNQGYIKRISMDTYRSQKRGGKGITAMGT-EEDFVRDLFIASTHHFLLFFTNKGKVYRLKVYEVPES-RTAKGTPIINLLSFDS-E
YVTTVIPIK---ETAYLFMATKHGIVKKTALTEYNS-RRDGLIAINLDEKDKLVAVE-THG-EEIIMCTQEGIAIRFSE--VRPMGRVTRGVKGITLS--
-NVVKMDVIK--ASLLTVTANGYGKRTPMDEYRIQARGGKGIINIKTT-K-NGAVTGVLVVSE-DEVMMISAEGIIIRINVKDVSSMGRNTQGVTLMRTG
ND-IVAIAKVI-
>tr|K1ZRC3|K1ZRC3_9BACT DNA gyrase subunit A OS=uncultured bacterium (gcode 4) GN=gyrA PE=3 SV=1
IEDLIQKEDMVVTVSHLGYIKRLPLTTYRTQRRGGKGKQGMMT-EEDFVEKIFTASTHDLMLVFTNQGRVHWLKVYEIPEASRTAKGKSISNLIQLAG-E
KIATILPIED----DLIVFATRAGTIKKTALSAYSN-RVGGIIAITLN-NDELISVK-VQK-QDIILSTAHGQSIRFDE--IRSMGRLAAGVRGITLK--
DTVVGMDVVE-GKTILTISAKGYGKRTELDEYRKQSRGGSGIITLKVT-E-TGQVINATEVTD-DHLMLITNGGKIIRQEVKNISIIGRNTQGVRLIDVD
-NLVVSATIFE-
>tr|T2NKV8|T2NKV8_ENTFC DNA topoisomerase 4 subunit A OS=Enterococcus faecium 13.SD.W.09 GN=parC PE=3 SV=1
TQVLVAQEEVVVTVTRDGYVKRSSLRSYGASK--P---------GD-SLLYS-NQNTLDHLLLVTNKGNTIYRPVHELPD-----LGEHISQTVMT-ADE
M--GVFAYK----LKNFVLISKNGMIKQTRMTEFE----RPMTIMKLK-SDELVN---D--EMDVFLVSHLAFGL------V--VGPKAAGVKAMNLKD-
-YLINGLLVYSDTPIVLITQRGAAKRMLAQ------RAKRGLMVL----RLPHRV-YMGNGE---QLLVTNQKGQAFEVIT-QIPI---TSNGSFIMDEK
G--IYEVKTQI-
>tr|A0A0I9WIC5|A0A0I9WIC5_9ENTE DNA topoisomerase 4 subunit A OS=Enterococcus cecorum GN=parC PE=3 SV=1
TEVLIASEDVMVTVTKEGYVKRSSLRSYAASN--F---------SD-CLLYC-EQNTLDHLLLFTNKGNVIYRPIHELPD-----IGEHISQTITK-ADE
T--AAFSYK----EPTLVLISKYGMIKQVQFAELT----KASTVMNLK-EDELVN---S--LQDVFLVTHQAYGL------V--SGPKAAGVKSMNLKE-
-YIVNGLLVYSDTPVVLVSQRSAVKRMLAQ------RAGRGLMVF----RLPHRV-FMGEGQ---TYQMQNQKGEVYELHP-EFPI---TSNGSMMMNET
G--VTSVEVIF-
>tr|G4L8L2|G4L8L2_TETHN DNA topoisomerase 4 subunit A OS=Tetragenococcus halophilus (strain DSM 20338 / JCM 20259 / NCIMB 9735 / NBRC 12172) GN=parC PE
TEVLVSSEEVMTAITQEGYVKRSSLRSYNASR--P---------SD-EVVFC-QQNTLDHLLLVTNKGNMIYRPVFELPD-----TGEHLSQNLLN-SDE
V--AVYSFN----SKNFVFMTQKGMIKQTHMDEFS----RATTAMKFK-SDELVS---D--ELDVFLASYKGMGL------V--VGSKASGVKAINLKD-
-EVTSGMLVYSDNPVIIVSQRGAIKRMLAQ------RAKRGVMIL----RLPHRI-YMGDGQ---TLLLTNEKGQQVEIES-QYPI---TSNGSFAIDEK
G--VLEVKEKF-
>tr|A0A091C2Z6|A0A091C2Z6_9ENTE DNA topoisomerase 4 subunit A OS=Tetragenococcus muriaticus PMC-11-5 GN=parC PE=3 SV=1
TEVLVPSEDVMTAITKEGYVKRSSLRSFSASK--A---------SD-KLVFC-QQNTLDSLLLITNKGNMIYRPVFELPD-----TGEHLSQNLLN-SDE
F--KVYSYS----AKNFVFITKDGMIKQTRMEEFK----RAATAIKFK-KDELVS---D--ELDVFIATYKGMGL------V--VGSKASGVKAINLKE-
-TVSNGLLVYSDNPVVIVTQRGAIKRMLAQ------RAKRGVTVL----RLPHRV-YMGEGQ---SLVLTNEKGDQVEIQS-HYPI---FSNGSFAIDEK
G--IIGVEEQL-
>tr|S1NFI4|S1NFI4_9ENTE DNA topoisomerase 4 subunit A OS=Enterococcus columbae DSM 7374 = ATCC 51263 GN=parC PE=3 SV=1
TEVLIAAEDVMVTVTKEGYVKRSSLRSYAASN--F---------SD-YLIMC-QQNTLDHLLLVTNKGNVIYRPIHELPD-----IGEHISQTILK-SDE
N--AAFSYK----VATFVLISKQGLIKQVKMDEFT----RFATMMNLK-NDEVVN---E--LQDVFVVTNQAYAL------V--SGPKASGVKSINLKD-
-YVVNGLLVYSDTPILLVSQRSAVKRMLAQ------RAKRGLMIF----RLPHRV-FMAEGD---GYTMFNQKGQSYPFTG-DFPI---TSNGSMMLDEQ
G--VIAVQPII-
>tr|A0A0N0KRK9|A0A0N0KRK9_9ENTE DNA topoisomerase 4 subunit A OS=Enterococcus sp. RIT-PI-f GN=parC PE=3 SV=1
TQVLVAQEEVVVTVTKDGYIKRSSLRSYGASK--P---------GD-ALLYS-HQNTLDHLLLVTNKGNVIYRPVHELAD-----LGEHISQNVLT-ADE
L--GVFAYK----MKNFVLISKKGMIKQSRMTEFE----RPLTIMKLK-ADELLN---D--PMDIFLVSQRAFGL------V--VGPKAAGVKAMNLKE-
-FIVNGLVVYSDTPVVIITQRGGAKRMLAQ------RAKRGLMVL----RLPHRV-YMGPGE---TLQITNQKGQTVEIET-QIPI---TSNGSFVTDEK
G--VYDVRAVI-
>tr|D4YDW1|D4YDW1_9LACT DNA topoisomerase 4 subunit A OS=Aerococcus viridans ATCC 11563 GN=parC PE=3 SV=1
KQLLIPEEDVVVVVTRGGYIKRSSLRSFKASG--I---------GD-HVQFL-EKSTLDQLVFITNKGNYIFQPVYELQD-----LGEHVSQRI-A-ADE
S--GVFKYD-----DNLLLASAAGMIKQTALSEFK----KSSLAMNLS-TDQVIG---D--QAQVILVTHFGFTL------I--IGVRAKGVKSINLK--
-DVVGLSYAAVNLQLMMVTQRGHMKRLKWA------RAKRGLVAL----KLPHRV-AAFEVI--QIFEVVTSQSHREMFRA-DVAI---YSNGSMLVDEK
H--ISLVTPLI-
>tr|F2I4X1|F2I4X1_AERUA DNA topoisomerase 4 subunit A OS=Aerococcus urinae (strain ACS-120-V-Col10a) GN=parC PE=3 SV=1
KEFLIPDEEVVTVVTRGGYIKRSSLRSYQSSN--F---------GD-HVLYL-AASTLDNLVLITNKGNYIFQPVYEMQE-----LGEHLSQRI-P-ADE
K--QVYPYA-----DTIVLATREGMIKQSKLSELK----KASQIMPLS-LDEVVN---N--NGEVILFTALGFSL------I--VGLRAKGVISINLK--
-DVVNFVYQDQDQQILLATQRGYMKRMRWR------RAKRGLMVL----RVPHRV-QALEVE--EVYELYTSNGELSQIKA-DVPL---YSNGSQIIDEG
L--LLDVIPLY-
>tr|A0A0K2FAJ6|A0A0K2FAJ6_9BACL DNA topoisomerase (ATP-hydrolyzing) OS=Paenibacillus peoriae GN=ABE82_14510 PE=4 SV=1
LEVMVGAEDVLLTLSKDGYVKRTSMLSFTRSG--GE--------GD-YVTQL-LDNTLDILLVFTQRGQYFLLPVHQVPE-----PGTPIVNVIPL-SED
R--SVIPLK---IGKSLVFVTKKGQVKRTELKEYA----SAVAACKVA-DEV-L----T--TQDIMLITRAGMSI------V--MGRVSAGVKGIQLA--
-DIIAALW-VEEGEVLVLTESGYGKRTLLL------RGGKGITTF--KGKVGTRV-AAFYCR---QLFAITAEGQTMSFLS-KAPL---KDTGKLLAPVE
K--IVNVLLRS-
>tr|D7UYJ9|D7UYJ9_LISGR DNA topoisomerase 4 subunit A OS=Listeria grayi DSM 20601 GN=parC PE=3 SV=1
KEVLVASEDVIVSVTKEGYVKRTSYRSYTASK--G---------TD-HAIFI-EKNTMDALLLFTSHGNFIYRPVHELPD-----LGDHVSHIVTEMGGE
E--QALPLS---T-QKLVFLTQAGMTKVSLIANYR----KAMMAIKLK-DKL-L----A--SEDIFIATRNGYGL------I--SGTRTAGVKAINLK--
-DVVGGVLLQSR-GIILTTQRGSMKKMKAS------RAKRGLLML----RLPHRI-DIRLAD---RLMVLTNKEQTVEIQV-NLRT---YSNGSFILDET
E--PIEVWTEI-
>tr|K1X2I5|K1X2I5_9BACT DNA gyrase subunit A OS=uncultured bacterium (gcode 4) GN=gyrA PE=3 SV=1
ELDLITEEDVIITLSQSGYIKRIPSDTYKAQKRGG-G--ISD--ED-TLLNFISGNTHDNILFFTHTGRVFQTKVYDVPQS-RTAKGKLMQNFL-DPE-E
N--AVIAYP---DGRYLVMLTADGTIKKTALSEFAN-R-TGIIAINLA--DSLIG---SD---DIIITTHAGQAI------AKPLGRAAAGVRGIKLKK-
-DVAGFDIIRAKQTLLVVSENGYAKQTPI-EYK-QTRGGMGIKTS---TPKIGNI-SGQIIR-EEELLAVSTRGQIIRIPL-DVRT-GR---GVKIMSLK
--KLAGVVAL--
>tr|J9HWJ0|J9HWJ0_9BACL DNA gyrase subunit A OS=Alicyclobacillus hesperidum URH17-3-68 GN=gyrA PE=3 SV=1
EEDLIPVHDVVIAITHRGYIKRIPLSTYHSQKRGGRGMSLMGT-DEDFVEGLHVTSTHDYLLFFTNRGRMYAIKAYDVPEFSRQARGIPIVNLLNVEQ-E
KINAVIPVKA-IEGINLVFATRQGIVKKTPLSEYSN-RKNGLIAINLRDDDDVVGVK-TDG-KEIMMVTRQGLAIRFPE--VRPMGRAATGVKGISLG--
-KVIAMDVAEDDHDVLVVTSRGYGKRTPVQEYRAQSRGGKGIKTINCT-P-NGQAIEMCMVTD-DDLMIISQSGVAIRIHVRDISTQSRNTQGVRLINVD
G-EVASVSRVV-
>tr|A0A0P9CHI8|A0A0P9CHI8_9BACL DNA gyrase subunit A OS=Alicyclobacillus ferrooxydans GN=AN477_17350 PE=4 SV=1
EEDLIPVQDVVVTITHAGYVKRIPLVSYQSQRRGGRGVTAMGT-EEDFVEHMFITSSHHYLLVFTNKGRMYSLKAYEIPEYSRQAKGLPIINLLQVDS-E
KISTVIPVRS--EDMKLFFATRQGIVKKTALKEYAN-RKNGLIAINLREDDQLISVR-TDG-KDIIMATSRGMSIRFPE--VRQMGRVSTGVKGIQLS--
-DVIGMDVVEPENDVLVVTSRGYGKKTHVSDYRVQARGGKGIKTLNCT-N-NGIVVGLKMVQD-DDLMIITNAGVAIRIHVADISTQSRNTQGVRLINVP
G-EVATVARVI-
>tr|A0A094K3Z8|A0A094K3Z8_9BACL DNA gyrase subunit A OS=Thermoactinomyces sp. Gus2-1 GN=gyrA PE=3 SV=1
IEDLIPEDEVSIMMTQRGYIKRVPLSTYRAQKRGGKGITGMGT-DDDLVQHMFVTHSHSTLLFFSNKGKVYRLKAYEVPELGRTAKGTPVINLIQIDQ-E
RIEAVIPVK---PNQFLFFVTAEGVVKKTALSEFEN-RRNGLFAINLRDGDDLVGVR-TDG-QEVIMGTRHGMSIRFHE--VREMGRSATGVKGITLG--
-GIIDMDIVVPDSYVMIVTENGYGKRTPIDEYRIQSRGGKGIKTLSLT-E-KGEVVAHKVVSN-EDLMIATQSGVVIRIKVADISIMGRYAQGVRLIRVD
D-EVSAVARVH-
>tr|C8WXT2|C8WXT2_ALIAD DNA gyrase subunit A OS=Alicyclobacillus acidocaldarius subsp. acidocaldarius (strain ATCC 27009 / DSM 446 / JCM 5260 / NBRC 15
EEDLIPVHDVVIAITHRGYIKRLPLSTYHSQRRGGRGMTLINA-EEDFVTGLHVTSTHDYLLFFTNRGRMYAIKAYDVPEFGRQARGTPIVNLLNIEQ-E
KVTAMIPVKA-IGDTYLFFATRQGIVKKTPLAEYSN-RKNGLIAINLRDDDDLVGVK-TDG-KEIMMVTRNGLAIRFPE--VRPMGRAATGVKGISLS--
-GVIAMDVAEDDHDVLVVTSRGYGKRTPVSEYRAQSRGGKGIKTLNCT-P-NGHAIEMCMVTD-DDVMIVTQAGVAIRIHVRDVSTLSRNTQGVRLINVD
G-EVASVSRVV-
>tr|A0A0N0YB50|A0A0N0YB50_THEVU DNA gyrase subunit A OS=Thermoactinomyces vulgaris GN=gyrA PE=3 SV=1
EEDLIPEDEVAIMMTHRGYIKRMPLSTYRAQRRGGKGITGMGT-DDDFVQHIFVTHSHNHLLFFSNKGKVYRLKAYEVPELGRTAKGTAIINLIQIDQ-E
RIQAIIPVK---ANQYLFFGTAEGVVKKTALSEFEN-RRNGLFAINLRDGDELIGVR-TDG-QEVIMGTRGGMSIRFPE--VREMGRSATGVKGITLG--
-DVIDMDIVIPDKNVMIVTRNGYGKRTPMEEYRVQSRGGKGIKTLSLT-E-KGDVIGHKVVSD-EDLMIVTQSGIVIRLNVNEISIMGRYAQGVRLIKLD
D-EVAAVAKVN-
>tr|T0C129|T0C129_9BACL DNA gyrase subunit A OS=Alicyclobacillus acidoterrestris ATCC 49025 GN=gyrA PE=3 SV=1
DEDLIPMHDVVIAVTHRGYIKRIPLSTYHSQRRGGRGMSLMGT-DEDFMEQLHVTSTHDYLLFFTNRGRMYAIKGYEVPEFSRQARGIPIINLLNIEQ-E
KITAVIPVQD-ISGINLFFATRHGIVKKTALSEYSN-RKNGLIAINLRDDDDVIAVK-TDG-KNIMMVTRLGLAIRFNE--VRAMGRGATGVKGISLN--
-DVIAMDVAEDDHDVLVVTANGYGKRTPVTEYRGQMRGGKGIKTMHCT-P-NGNVIEMRMVTE-DDLMIITQSGVAIRIHVKDISTQSRNTQGVRLINVA
G-EVATVSRVM-
>tr|A0A0J1EWJ8|A0A0J1EWJ8_9BACL DNA topoisomerase (ATP-hydrolyzing) OS=Paenibacillus sp. VT-400 GN=EL84_24965 PE=4 SV=1
LEVLVNAEDVFVTLSKEGYVKRTGMQSFTRSG--GE--------GD-YIAQV-LENTLENLLVFTRKGQYFLLPVHQVPE-----PGTAIVNVIPL-ADD
R--SVLAVK---PNHSLVFVTRRGQVKRTELKDYV----GAVAACKVG-DEV-L----H--GQDIMLITKEAMAI------V--MGRVSGGVRGIQLR--
-DVVSALW-VEEGEVAVLSDLGYGKRSLLL------RGGKGLATF--KGKVGSRV-GAFYCK---KITVMTKEGQVFPISS-GVPI---KHIGKLIVHVD
Q--IVELLRDF-
>tr|A0A0Q7SRL6|A0A0Q7SRL6_9BACL DNA gyrase subunit A OS=Paenibacillus sp. Root52 GN=ASD24_08390 PE=4 SV=1
LEVLVNAEDVFVTLSKEGYIKRTGMQSFSRSG--GE--------GD-YISQV-LENTLENLLVFTKKGQYFLLPVHQVPE-----PGTAIVNVIPL-ADD
R--TVLAVK---PNHSLVFVTRKGQVKRTELKEYV----GAVAACKVG-DEV-L----H--DKEIMLITKEAMAI------V--MGRVSGGVRGIQLK--
-DVVAALW-VEEGEIAVLSDLGYGKRSLLL------RGGKGLATF--KGKVGSRA-AAFYCR---SFNLMTKEGHTHAISS-GVPI---KHIGKLLVHVD
Q--IMELLGDF-
>tr|R7CPX9|R7CPX9_9FIRM DNA gyrase subunit A OS=Dialister sp. CAG:357 GN=gyrA PE=3 SV=1
MTDLIPDEPMTITLTKQNYIKRMDSADIRVQRKGGRGVSGMKM-DEDYVWKLLSTSTHNRILFFTNKGKVYMKTAVEFPKG-RTARGSALINFIPGGPDE
RVTELLDID-G-DMKYLLMVTKKGYIKKTEISEYKNINKNGLIAVRLNDGDRLVTVLAVKGDEEIIIGTRQGMAIRFSI--VRTMGRATAGVHAIRLSDG
-EVVGAVLAT-DKDIFTISADGNAKRNKSSAYH-QGRNGRGVRNFKKG----YEVVALVAAD-NDELVGVSEQGITIKTKASQISSKARAGQGVILQRLE
-GRIASIDVIS-
>tr|F2BWE4|F2BWE4_9FIRM DNA gyrase subunit A OS=Dialister micraerophilus DSM 19965 GN=gyrA PE=3 SV=1
LTDLVPDEPMTITVTKHNYIKRMESSDIRIQRKGGRGVSGMKM-DDDYVWKIMNTSTHNRLLFFTDEGKVYLKSVIEFPLS-RTARGSALINFIPTEKDE
RVTEMLDPD-S-GVKYLLMITRYGYVKKTLIEEYKHINKNGIIALRLNEGDRLVKVIPVVGDEDVILGTRKGMAIRFSI--IRAVGRVAAGVHGIKLS--
-EVVGAVIAD-EKDIFTISADGNAKRNKESAYH-QGRNGKGVRNFKRG----FEVVALVAAD-NDELVGVSEGGITIKTSASQISSKAKAGQGVILQRLE
-GRIASIDVVP-
>tr|R7PRJ8|R7PRJ8_9FIRM DNA gyrase subunit A OS=Dialister sp. CAG:588 GN=gyrA PE=3 SV=1
VTDLIPDEPMVIIMTKQNYIKRMSVDTWRAQARGGKGVIGIRT-EGDYVWKVLNTSTHHRILFFTNTGRVYMRSAFDIPENNRNSKGSALINFIPSTPGE
KVTELFDVD-ADTAKYLFMVTKKGFVKKTETVEYKNIRQNGLIAVKLREGDSLVTVHHVAGGEKVFLATKDGMGICFP---VRAMGRATGGVRGIDLK--
-EVIGAVIAEEGKDIITISSDGQAKRNPISSYR-QSRNGKGTRNFKRG----YEVVAVVTAA-DDELVGVSEKGVTIKVRVADITAKSRGSQGVSIQNLE
-GRVASIDNIP-
>tr|R5T899|R5T899_9FIRM DNA gyrase subunit A OS=Dialister invisus CAG:218 GN=gyrA PE=3 SV=1
VTDLIPDKPMTITLTKQNYIKRIDSSDLRTQKKGGRGVSGLKM-DGDYVRKILTTSTHDRILFFTNKGKVYMKTAYDIPES-RNARGSAMINFITSGADE
HVTELLDLD-S-GTKYLLMVTKYGYIKKTALEEYKNINKNGLIAMRLKDEDRLVAVLPVKGDEEIIMGTRKGMAIRFSI--VRPLSRSASGVHGMRLK--
-DVVGVVVAA-EKDIFTISADGNAKRNAASAYR-QGRNGQGTINFKKG----YEVVALVAAD-RDELVGISEQGITIRIPANQISSKAKGGQGVILQRLE
-GRIASIDVVS-
>tr|R6A4A0|R6A4A0_9FIRM DNA gyrase subunit A OS=Dialister sp. CAG:486 GN=gyrA PE=3 SV=1
LTDLIPDEPMTITLTKQNYIKRMDSADIRVQKKGGRGVSGMKM-DEDYVWKILNTSTHNRILFFTNKGKVYMKTAVEFPKT-RTARGSALINFIPNARDE
RVTELLDID-V-GTKYLLMVTKKGYVKKTELAEYKNINKNGLISIRLNEGDRLAAVLAITGEEEIILGTKDGMAIRFSV--VRSMGRAAAGVHGIKLA--
-EVVGACIAA-DKDIFTISADGNAKRNKASAYH-QSRNGKGIRNFRRG----YEVVALVAAD-KDELVGVSEQGITIKTKASQIVSKTKAGQGVILQRLE
-GRIASIDVLS-
>tr|G5KGJ5|G5KGJ5_9STRE DNA topoisomerase 4 subunit A OS=Streptococcus urinalis 2285-97 GN=parC PE=3 SV=1
TASLIVEEDTIVSVTSGGYIKRTSPRSYNSSS--N---------DD-DLIFV-KPKTTQQLVLFTNQGNVIYRPIHELTD-----IGEHLSQTITN-TEE
T--HVEIVE---QLY--VSVTKKGQIKRFERKEVS----KSTKFMKLK-DDSVIC---Q---EDMVLITEFGYAL------I--LGSKAAGVKAINLK--
-DLVAAYPMTS-QMIYILTQRGSLKRISLS------RANRGLLVL----RLPHRF-DSGIIN-KQVLEITSKTGQIYQVEL-QLPL---TSNGSFISDSI
T--VFSSKVKT-
>tr|K8ZCD1|K8ZCD1_9ENTE DNA topoisomerase 4 subunit A OS=Catellicoccus marimammalium M35/04/3 GN=parC PE=3 SV=1
EEQLIPSENTMVAITKNGYLKRSSLRSVQSSG-GV---------ED-DFIFM-EENTRDFLYLLTNKGKMIYRPVYEVID-----VGDHITESISN-EEE
E--YVFHFT---IEERLLFVTRQGLVKQMSWEELR----KAQICYKWK-NESFLW---S--NFTLYLFTHLGYSL------I--TKTKASGIKAINLK--
-DLVSAFVMEDSTSLVTVTQRGAMKQMPLL------RAQRGILVL----KIPHFV-YAAPIQ--VVTYET-KNGYIAKVEV-NIRN---ESNGTMMIDEK
E--IISAQ----
>tr|X5IYK2|X5IYK2_9FLAO DNA topoisomerase (ATP-hydrolyzing) OS=Candidatus Sulcia muelleri PSPU GN=gyrA PE=4 SV=1
--NEVYNNKFVITITKTGYIKKNNLNKYKIKNIGG-E--L-TY-KN-NLEKIIIAKNYQDILFFSENGKYFLLKVFKIPEL-KKSKGQAIQNLL-KNK-E
K--SSILIEK-LNKNSVILITKNGIIKKQTLIQYYK-K-KLI---KII--DYLID-------SEILIASKSGKII------ITNIPLKSKSVTL--SKN-
-DIIDIICLNDKIYILGVSEKVFV-KISN-RYK-ICKGLKKINVT---TVF---L-AIKNVI-KNDIIIINKYGLTFRIPV--FFL------GRI--KLK
Y-KITYVAKVE-
>tr|I3QG60|I3QG60_9FLAO DNA gyrase subunit A OS=Blattabacterium sp. (Blaberus giganteus) GN=gyrA PE=3 SV=1
IEDLIENEQVVLTISHAGYIKRTSLSEYKRQGRGGVGNRGATA-ESDFFKHLLVATNHQYLLFFTEKGKCFWLRVYEVPEGTKISKGRAIQNIIHLQEGD
KVNAYILTG-L-KDYYVMMITQKGIIKKTSLESYSRPRKYGINAIVIRKGDSLLEAILTKGRLTNFIAVKSGRIIRFSE-KVRSTGRTSSGVIGININEM
-MVIGMICVDIKGQLLVVSEKGFGKRSHIKDYRITNRGGKGIKTI--TQ-KTGSLISIKYVTDQDDLMIIKKSGIIIRIPVSDIRVMGRTTQGVRLIHLK
-NFNEIP-----
>tr|A0A088MZ36|A0A088MZ36_9FLAO DNA gyrase subunit A OS=Candidatus Sulcia muelleri GN=gyrA PE=3 SV=1
---LEPNKQVVLTTSYDGYMKRTDLNEYKIKKVGG-V--MAY--KD-FIKHILVANTHQYMLFFTEKGKCFWLRVFEIPEY-KTSKGRAIQNLI-KDK-D
K--SSILIKK-INNHYVIMITKSGIIKKTTLEQYSK-N-NGINAIKIK--DALID---T---SEILIAVKSGKAI------VRPMTRITLGVKSITLS--
LLVIGMICI--KEYILVISENGFVKISNL-HYR-TD---QGIKTI---TSKTGCV-AIKNVV-KDDIIIINQSGLTLRIPV-EIIV-VSKGKGIKLINLK
K-A--SVAKVD-
>tr|G7SPS2|G7SPS2_9FLAO DNA gyrase subunit A OS=Blattabacterium sp. (Mastotermes darwiniensis) str. MADAR GN=gyrA PE=3 SV=1
MEDLIEDEQVVLTISHAGYIKRTSLSEYKCQGRGGFGNRGAIA-ESDFFKHLLIATNHQYLLIFTEKGKCFWLRVYEIPEGSKISKGRAIQNMIHLQPDD
KVNAYILTGT--KNHYVMMVTQKGMVKKTSLKHYSR-RKDGIKAIVIREGDSLLEAILIKGNSHIFIAVKSGKIIRFS---VRSTGRMSSGVIGINLTP-
-DVIGMICLEKGQHLLVVSDKGFGKRSNLK-YRITNRGGKGIKTINITQ-KTGSLIAIKKVT-QDDLMIIKKSGIIIRIPVSDIRVMGRDTQGVKLINLK
-NEIADVEKVY-
>tr|G8LQT4|G8LQT4_9FLAO DNA gyrase subunit A OS=Blattabacterium sp. (Cryptocercus punctulatus) str. Cpu GN=gyrA PE=3 SV=1
IEDLIDDEQVVLTISHAGYIKRTSLSEYKCQGRGGVGNRGASA-ESDFLNHLLIATNHQYLLFFTEKGKCFWLRVYEIPEGSKISKGRAIQNMIHIQKDD
KVNAYILTGT--QNHYVMMVTKKGIIKKTSLENYSR-RKDGIKAIIIREGDSLLEAILTKGKSHVFIAVKSGRIIRFS---VRKTGRTSSGVIGINLK--
-DVIGMICVEEGN-VLVVSDKGFGKRSNLK-YRITNRGGKGIKTINITK-KTGSLISIKHVK-QDDLMIIKKSGIIIRIPISDIRVMGRSTQGVRLIYLK
-KEIADVEKID-
>tr|D0J8V5|D0J8V5_BLASP DNA gyrase subunit A OS=Blattabacterium sp. subsp. Periplaneta americana (strain BPLAN) GN=gyrA PE=3 SV=1
IEDLIEDEQVVLTISHAGYIKRTSLSEYKRQGRGGIGNRGASA-ESDFFKHLLIATNHQYLLFFTEKGKCFWLRVYEIPEGSKISKGRAIQNMIHLQPDD
KVNAYILTGT--QNHYVMMVTQKGIIKKTSLENYSR-RKDGINAIVIRKGDSLLEAILTKGNSHVFIAVKSGKIIRFS---VRATGRNSSGVRGINLSS-
-DVIGMICVEGGY-LLVVSEKGFGKRTNLK-YRITNRGGKGIKTINITQ-KTGSLISIKHVT-QDDLMIIKKSGIIIRISVSDIRVMGRDTQGVRLINLK
-KEIADVEKVS-
>tr|D0JBG1|D0JBG1_BLASB DNA gyrase subunit A OS=Blattabacterium sp. subsp. Blattella germanica (strain Bge) GN=gyrA PE=3 SV=1
IEDLIENEQVVLTISHAGYIKRTSLSEYKRQGRGGVGNRGATA-ESDFFKHLLIATNHQFLLFFTEKGKCFWLRVYEIPEGSKISKGRAIQNIIHLQQDD
KVNAYILTG-L-KDYYVMMVTQKGIIKKTSLENYSRPRKDGINAIVIRKGDSLLEAILTKGDSHVFIAVKSGRIIRFSE-KVRSTGRTSSGVIGIHFT-K
-MVIGMICVDGKGHLLAVSEKGFGKRSNLKDYRITNRGGKGIKTI--TQ-KTGYLIAIKHVTDQDDLMIIKKSGIIIRISVSGIRVMGRTTQGVRLINLK
-NAIADVAKVY-
>tr|D4G392|D4G392_BACNB DNA gyrase subunit A OS=Bacillus subtilis subsp. natto (strain BEST195) GN=gyrA PE=3 SV=1
DEDLIERENIVVTLTHNGYVKRLPASTYRSQKRGGKGVQGMGT-EDDFVEHLISTSTHDTILFFSNKGKVYRAKGYEIPEYGRTAKGIPIINLLEVEK-E
WINAIIPVT---AELYLFFTTKHGVSKRTSLSQFAN-RNNGLIALSLREDDELMGVR-TDG-KQIIIGTKNGLLIRFPE--VREMGRTAAGVKGITLT--
DDVVGMEILEEESHVLIVTEKGYGKRTPAEEYRTQSRGGKGLKTAKIT-ENNGQLVAVKATKE-EDLMIITASGVLIRMDINDISITGRVTQGVRLIRMA
-EHVATVALVE-
>tr|A0A0R1RYJ5|A0A0R1RYJ5_9LACO ParC protein OS=Lactobacillus fuchuensis DSM 14340 = JCM 11249 GN=FC69_GL000917 PE=4 SV=1
TSVTVIDETVMVSISHDGYLKRSSLRSYQASD------------GD-FAILQ-KPQTLDQLMLFTNYGHLIQRPVHEIAD-----MGEHISQSI-G-ADE
A--AAFAFD---HAGHFVIGSTDGYIKQTEFADLL----KAQDCIKLH-AKVTNV---A--QTAVFSASYHGYGL------V--SGAKASGVKLMDLK--
-DVANFTLFNPQASVAILTQRGAFKRMMLS------RARRGVLIL----RLPHRV-AMSLVT-GAELLIQTDQ-QLITINP-THVT---YSNGSFIFDID
V--PEFIL-TV-
>tr|A0A0R1WX45|A0A0R1WX45_9LACO ParC protein OS=Lactobacillus graminis DSM 20719 GN=FC90_GL001101 PE=4 SV=1
TSVTVIDETVMVAVSHDGYLKRSSLRSYQASD--E---------GD-FAILQ-KPQTLDQLMMFTNYGHLIQRPVHEIAD-----MGEHISQSI-G-ADE
A--AAFAFT-G-QAGYFVIGTDDGYIKQTAFTDLL----KAQDFIKLH--AHVTN---P--GLVVFSASYKGYGL------V--SGAKASGVKLMDLK--
-DVTNFILYDSHAAVAIMTQRGAFKRMLLS------RARRGVLIL----RLPHRV-AMVGV--KMLLLIHTNQQQVITLNP-QHAT---YSNGSFVMDID
V--PQFIQSTV-
>tr|A0A0B2XL57|A0A0B2XL57_LACCU DNA topoisomerase 4 subunit A OS=Lactobacillus curvatus GN=parC PE=3 SV=1
TSVTVVDETVMVAVSHDGYLKRSSLRSYQASE--G---------GD-FAILQ-KPQTLDQLMMFTNYGHLIQRPVHEIAD-----MGEHISQSI-G-ADE
A--AAFAFK-N-QAGYFVIGTDDGYIKQTAFSDLL----KAQDFIKLH--AHVTN---P--GLAVFSASYKGYGL------V--SGAKASGVKLMDLK--
-DVTGFTLYHPHAAVAIVTQRGAFKRMLLS------RARRGVLIL----RLPHRA-AMVSV--ASELLIHTDQQEVIAINP-QHAT---YSNGSFVMDVD
V--PAFVQTTI-
>tr|N4W9L8|N4W9L8_9BACI DNA topoisomerase 4 subunit A OS=Gracilibacillus halophilus YIM-C55.5 GN=parC PE=3 SV=1
VEVTVASEDVIVSVTDNGYVKRTSTRSYGASK--D---------DD-YLLRL-MENTTDYLLIFTSNGRFVPFPVHQLPD-----LGQHFSNLVSL-EDE
T--EVIPIR----DHYLVFFTQNGMVKKSKLDLYQ----RPLIALNLK-DQL-V----H--HTDVFVVSNKGYGL------V--IGQRATGVKAMQLK--
-EIINGVVFDEPSQLFVATQRGACKRMTLN------RAKKGQALL----RLPHYV-GFDQMN---RFILKTNEGTEREISP-DLPN---HSNGSFVIDTD
D--ITSIWKKA-
>tr|E7GAZ5|E7GAZ5_9FIRM DNA gyrase subunit A OS=Coprobacillus sp. 29_1 GN=gyrA PE=3 SV=1
DEDLIPVEDIIISLTTNGYVKRMPVDTYKTQNRGGRGIKGMAT-EDDIVDSLINMSTHDDLLFFTNFGKVYRIKGYNVPEG-RTAKGLPVVNLLNLDK-E
YVKSMISIR--KKAEYLFFVTLNGLVKKTHIDEFEN-RQSGKIAIGLKEDDQLVSVK-TTG-AQILVAASNGKLIRFKE--VRKMGRTASGVRGINVD--
-GVIGMTTDQE-QFIMAISENGYGKMSPLDDYRESHRGGKGVKTINTT-A-TGQLVALRAV-G-EDLLIITSEGIVIRLPMDQVKTAGRNTQGVRLIKVA
GS-VSSVEVVE-
>tr|R7GLN5|R7GLN5_9FIRM DNA gyrase subunit A OS=Catenibacterium sp. CAG:290 GN=gyrA PE=3 SV=1
DEDLIPEEDVVISLTNNGYVKRMPIDTYKAQNRGGKGIKGMST-NDDVVDSLMNMSTHDDLLIFTNFGKVYRMKGYNIPEG-RQAKGLPIINLLNMDK-E
QVKTMISIT---ESHFLFFVTKDGLVKRTGLPEFEN-RQSGKLALTLREGDELVDVK-TNG-SEILLAAANGKAIRFDE--VRPMGRSASGVKGMNVD--
-SIIGVTTNTE-QNILIITEKGYGKMSPLEEYRLSKRGGKGVKTVNIT-E-NGELVSIKAV-G-EDLMIITNEGIIIRLPMEQVKSAGRATQGVRLIKVG
GA-VSSITVVD-
>tr|A0A0R2H4H7|A0A0R2H4H7_9FIRM DNA gyrase, A subunit OS=Kandleria vitulina DSM 20405 GN=IV49_GL001334 PE=4 SV=1
DEDLIPVDDIIISLTTNGYVKRMPVDTYKAQNRGGKGIKGMAT-NDDVVDSLLNMSTHDHLLFFTNAGKVYRLKGYNIPEG-RTAKGLPIINLLNMDK-E
SIKSMISIK---DKNFLFFVTKKGIVKRTPLAEFER-RQTGKIAISLKDDDELVDVK-TDG-SEILLAAANGKAIRFDE--VRAMGRSASGVRGMNVD--
-SVIGMTTNSE-EKIMIVTANGYGKMSSLDEYRLAKRGGKGVKTVNIT-N-NGQLVALRAV-G-EDLMIMTSEGIIIRLPMEQVKFAGRATQGVRLIRVD
GA-VSSISVVE-
>tr|G9R3J5|G9R3J5_9FIRM DNA gyrase subunit A OS=Coprobacillus sp. 3_3_56FAA GN=gyrA PE=3 SV=1
DEDLIPVEDVIISLTNNGYVKRMPVDTYKTQNRGGRGIKGMAT-SDDIVSSLINMSTHDDLLFFTNFGKVYRLKGYNIPEG-RSAKGLPVVNLLNLDK-E
QVKSMISIN--NNDYYLFFVTASGLVKRVHINEFER-RQSGKIAISLRDDDQLVSVK-TGG-DQILIAASNGKLVRFEE--VRPMGRSASGVKGINVD--
-SVIGMTTDKE-KYIMVVTERGYGKMSPLEEYRLSNRGGKGVKTINAT-E-NGQIVALRAV-G-EDLLIITDDGIMIRLPMEQVKTAGRATQGVRLIKVN
EN-VSSVEVVE-
>tr|B1C5H9|B1C5H9_9FIRM DNA gyrase subunit A OS=[Clostridium] spiroforme DSM 1552 GN=gyrA PE=3 SV=1
DEDLIPVEDVIISLTNNGYIKRMPVDTYKSQNRGGRGIKGMST-NDDIVSSLINMSTHDDLLFFTNFGKVYRLKGYNIPEG-RSAKGLPVVNLLDLDK-E
SIKSMINID--NSNYYLFFVTKDGIVKRVHINEFQL-RQSGKIAICLKDNDQLVQVK-TSG-DQILIAASNGKLVRFEE--VRPMGRISSGVKGINVD--
-SVVGMTTDKE-KYILVVTERGYGKMSPLEEYRLSNRGGKGVKTIHTT-E-NGKIVALRAV-G-EDLLIITDDGIMIRLPMEQVTTAGRATQGVRLIKVN
NN-VSSVEVVE-
>tr|M2Q614|M2Q614_9FIRM DNA gyrase subunit A OS=Eggerthia catenaformis OT 569 = DSM 20559 GN=gyrA PE=3 SV=1
DEDLIPVEDVIISLTNNGYVKRMPVDTYKAQNRGGRGIKGMTT-NDDVVSSMLNMSTHDDLLIFTNFGKVYRLKGYQIPEG-RTAKGLPIVNLLNLAK-E
LVKSMISLH---KENYLFFVTRRGLVKRTNLTEFEN-RQSGKLAITLKEEDELVDVK-TNG-CEVMIATTNGKAIRFDE--VRSMGRTAAGVRGMNVE--
-NIIGMTTSLE-SKILVVTEYGYGKMSPAHDYRLAKRGGKGVKTLNIS-S-NGKLVAMKAV-G-EDLMIMTNEGIIIRLPMEQVKEAGRATQGVRLIRVN
S--VSSISVVE-
>tr|C8NEP4|C8NEP4_9LACT DNA topoisomerase 4 subunit A OS=Granulicatella adiacens ATCC 49175 GN=parC PE=3 SV=1
TEVLVTEEEVYVVATKQGYYKRVSPRSFASSA--P---------GD-EVVLC-QKSTLDNLILFTSKGNYLHLPVHEIPE-----VGNHLSQSI-S-GNE
V--TGFVKADS-KDWTVVFFTKEGLVKQTLFNEFT----RTSNAMKLK-TDEVVK---T--SLEVFIVTHCGFGL------I--VGTVASGVKAINLR--
-DVAGAMVYSLVVSAFLTTQRGAVKRFNVL------RAKRGLMVL----RLPHRV-FLDGEI--SEYTIIAGNGETKVVRP-DLTL---TSNGSMLLGDN
Q--KAVLANFD-
>tr|D0BKA5|D0BKA5_9LACT DNA topoisomerase 4 subunit A OS=Granulicatella elegans ATCC 700633 GN=parC PE=3 SV=2
TEILIPEEEVYVVATKQGYYKRVSPRSFASSA--P---------GD-EVLLV-QKSTLDSLVLFTSKGNYLHLPVHEIPE-----VGHHLSQSI-S-ANE
I--AGMVKEDA-QDWTVVFFTKEGLVKQTAMNEFN----RTSNAIKLK-TDEVVA---P--EQEIFIVTHCGFGL------V--VGTVASGVKAINLR--
-DVAGAMVYSPVVSAFLATQRGSVKRFNVL------RAKRGLMVL----RLPHRV-YLDGNI-KQEYVIVSTNGEMKEIRP-DLSL---TSNGSALLNDA
D--TKSVLKKF-
>tr|W1Q2R2|W1Q2R2_ABIDE DNA topoisomerase 4 subunit A OS=Abiotrophia defectiva ATCC 49176 GN=parC PE=3 SV=1
THILIPDEQVMVSLTKEGYMKRTSMRSFASSD--L---------FD-YPIFV-EESTHQELVIITSKGNYIHIPVHELPE-----LGVHLSQNYQL-QGE
R--NAFVAS--QEEHKVILATKAGMIKQTPLSAFT----RTAKAMNLL-QDEVVA---K--NYEVVLLSRRSYCL------V--MGLKAKGVTAIKLK--
-DVVACLVVNQRPQLFALTQRGNVKRSDLT------RGSRGVLLL----KLPHQL-KVLALD--HQVCLLGDTGHSVVFAA-EIPL---LANGSQAPDLA
L--ILDCYLVL-
>tr|F5L548|F5L548_9BACI DNA gyrase subunit A OS=Caldalkalibacillus thermarum TA2.A1 GN=gyrA PE=3 SV=1
DEDLIPQEKVIISLTHKGYIKRLPVSTYRSQKRGGRGITGLGT-EDDFVEHLFVANTHDFILLFTNKGRVYRLKAYEIPELGRTARGLPIINLIQIEK-E
YITALIQVE---PHRYLFFATRQGIVKRTALHDFEY-RRGGLFAINLRDNDELISVR-TDG-QEIIMGTKKGMAIRFSE--VRVMGRAAAGVKGITLR--
-DVIDMDVVKKDHDVMIVSRNGYGKRTSIDEYRIQSRGGIGLKSYNVT-E-CFEVVGLKTVAN-DDFMLVTSSGLIIRIHVNEVSQLSRYARGVRLIRLQ
D-EVATVAKVQ-
>tr|B7CCH3|B7CCH3_9FIRM DNA gyrase subunit A OS=Holdemanella biformis DSM 3989 GN=gyrA PE=3 SV=1
DEDLIPVEDVIITLTESGYIKRQLVDTYRAQNRGGRGIKSLTL-EEDSIDTMISMSTHDFLLLFTDKGRVYRLKGYNVPS-SRTSKGIPIVNLMTLEKGE
KVNVLVAVP---ESETLLFVTKNGIVKRTSVSEFENINRNGKIAISLKPDDELRFVKLTTGQDEVIISGSNGKAVRFN---VRIMGRSASGVLGFNCD--
-EVVGAAL-S-GDTVLVVSENGYGKRSKFEDYRLTSRGKKGVSTINITE-KTGKLMCMRAVT-KEDAMIVASDGIMIRVALENVGI-GRNTQGVRLINLN
GDKVTRMTLVD-
>tr|U2PE93|U2PE93_9FIRM DNA gyrase subunit A OS=Faecalitalea cylindroides ATCC 27803 GN=gyrA PE=3 SV=1
DEDLIPVEDVIIMLTESGYIKRQSVDTYKAQNRGGRGIKSLTL-EEDSIDTMISMSTHDYLLLFTNTGRVYRMRGFNVPN-SRTSKGIPIVNLLTLEKGE
QIKTLQPVP--IEFKNLLFVTKNGIVKRTSISEFENINRNGKIAISLKENDELAFVKLTTGNDEIIIAGSNGKAVRFN---IRVMGRSAAGVTGFNCD--
-EVVGVAL-S-GKTILSISENGYGKRSYLEDYRLTSRGKKGVRTINITE-KTGKLVSVKAVN-DEDVMIVSSSGIMIRTSLQNVGI-GRNTQGVRLINLT
DDKVTKVTLVD-
>tr|A0A0A6VEN4|A0A0A6VEN4_9BACI DNA gyrase subunit A OS=Bacillus ginsengihumi GN=gyrA PE=3 SV=1
DEDLIPRENIAITLTHNGYIKRLPISTYRSQKRGGRGIQGMGT-EDDFVEHLLTTSTHDTILFFTNKGKAYRKKGYEIPEFGRTAKGIPIVNLLEIDK-E
WINTMIRVE---ENSYLFFTTRSGISKRTPLSDFAN-RTNGLIAIHLKEEDELISVK-TDG-KDIIIGTKNGMLIRFPE--VRSMGRTATGVKGITLS--
NDVVGMEILEENNDVLIVTKNGYGKRTKEEEYRVQSRGGKGLKTCNIT-SKNGPLVAVKTVTE-EDLMLITAGGVMIRIAVDEISCLGRNTLGVKLIKLD
-DYVATVAKVE-
>tr|V6IU74|V6IU74_9BACL DNA gyrase subunit A OS=Sporolactobacillus laevolacticus DSM 442 GN=gyrA PE=3 SV=1
DEDLIEREDIVITVSHNGYVKRMPVNTYRSQNRGGRGVQGMGT-EDDFVEHLFQTNTHHHVLFFTNKGRVYQLKGYQIPEFGRTAKGIPIINLIQIEK-E
YITAFFPVE---DDHFLVFLTKNGITKRSPLSDFSN-RKGGLFAITVRDEDELIAVR-TDG-RDLIVGTKKGMAIRYHE--VRAMGRTAAGVKAITLD--
GDVVGMGIADEQLDVLIVTENGFGKRTAISEYRPQTRGGKGLKTCNIT-EKNGELVALRTVEN-EDLMIMTANGVIIRMPVSGISKLGRNTMGVTLIRVD
GVTIARIQSND-
>tr|A0A0H4NUF1|A0A0H4NUF1_9BACI DNA gyrase subunit A OS=Bacillus smithii GN=gyrA PE=3 SV=1
DEDLIPEENIVISLTHNGYIKRLPLSTYKSQKRGGRGIQGMGT-ENDFVEHLITTSTHDTILFFTNKGKVYKTKGYEIPELGRTAKGIPIINVLGIEK-E
WINTMIAVE---ENWYLVFTTKHGITKRTPLREYAH-RTNGLIALTLRENDELISVK-TDG-QDIVIGTKNGMMIRFKE--VRSMGRTSTGVKGITLD--
DDVIGMELLHDGEEVLIVTRNGYGKRTHEAEYRIQGRGGKGLRTCRIT-PKNGPLVAIKTISE-EDIMLMTAGGVLIRMDVQDISRTGRNAQGVKLIRLD
-DYVATVAVVE-
>tr|R4JXX2|R4JXX2_CLOPA DNA gyrase subunit A OS=Clostridium pasteurianum BC1 GN=gyrA PE=3 SV=1
IEDLIEDEDVVITLTHAGYIKRLPADTYTAQRRGGRGIQAMAT-EDDFVEHIFITSTHNNILFFSNQGKVYKLKAYEIHEG-RTAKGTNLINLLQLNQ-E
KIQAVITLK---EDNYLIMATKKGVIKKTSLDQYAA-RKNGLNAINLREDDELIGVR-TNG-SEILMATKNGYAIRFNE--ARPLGRNTSGVRGISLR--
-DVVGMEVVDI-QDVLVVSSNGFGKRTHIAEYSVQKRGGKGVITYKVT-E-TGELVGARMVKA-DEMMIINSNDIVIRINVSDISTTSRNAMGVTLMRST
EE-VVAIAKID-
>tr|A0A0G1KAT9|A0A0G1KAT9_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWF2_44_8b GN=gyrA PE=3 SV=1
IEDLVAEEENTLVLTSGGYIKRTNPDEYKRQKRGG-G--VLD--ED-FVTNFLTASTHADLLFFTDKGKVYQIKMYDIPEK-RATRGKSVLNFI-SSD-E
K--SILAMPTSTREGSLFMVTENGTAKKVSVKSFQD-R-SGIIAIKLS--DKLIS---V---DDISIVTKKGQSI------IREMGRSAGGVRGIKLDG-
-IVVGAHHIKPSGHLLVISANGYGKRTSL-EYK-QGRGGSGILTS---TSKTGQI-ASQVVT--EEVIAISKKSQVVRVGL-EIPA-GR---GVRIMKLR
G-SIASLICL--
>tr|A0A0L0LEN2|A0A0L0LEN2_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium C7867-005 GN=gyrA PE=3 SV=1
VEDMIAEEENALVLTSGGYIKRTNPDEYKKQKRGG-G--VLD--ED-FVTHFLTASTHSDLLFFTDKGKAYQIKMYDIPEK-RATRGKSIMNFI-SSD-E
K--SILPMSN--IKGALLMVTEDGTAKTVDAKSFFD-R-SGIIAIKLA--DRLVS---V---DDATIVTKEGQSI------IREMGRGAAGVRGIKLAG-
-KVIGAHEIKKSAHLLVISANGYGKRTDL-EYK-QGRGGSGILTS---TDKTGKM-ASQIVT--EEVVAISKKSQVVRVDI-EIPV-GR---GVRIMKLR
G-SLASLICL--
>tr|A0A0G0P1W9|A0A0G0P1W9_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWB1_38_8 GN=gyrA PE=3 SV=1
VEDLVAEEENALVLTSGGYIKRTNPDEYKRQKRGG-G--VLD--ED-FVTNFLTASTHADLLFFTDRGKAYQIKMYDIPER-RATRGKSVMNFI-SSD-E
K--SILAMPN--IKGSLFMVTECGTAKKVSAKSFTD-R-SGIIAIKLA--DKLKS---V---DDVSIVTQDGQSI------IREMGRSAGGVRGIKLAG-
-AVVGAHVIKTDGHLLVISANGYGKRTKL-EYK-QGRGGSGILTS---TTKTGVI-TSQVVT--EEVIAISKKSQVVRIDI-EIPV-GR---GVRIMKLR
G-SLASLICL--
>tr|A0A0G1VUV9|A0A0G1VUV9_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWB1_49_7 GN=gyrA PE=3 SV=1
VEDLVAEEDNALVLTSGGYIKRTNPDEYKRQKRGG-G--VLD--ED-FVTNFLTASTHDDLLFFTDKGKAYQIKMYDLPEK-RATRGKSIMNFI-ASE-E
K--SILPMP--KSSGSLLMVTEMGTVKKVSAKSFTD-R-SGIIAIRLA--DRLVS---VD---DISIVTRKGQSI------LREMGRAAGGVRGIKLEK-
-NVVGAHVITKSGHLLVISGNGYGKRTKL-EYK-QGRGGSGILTS---TPKTGPI-TSQIVS-EEEVIAISKKSQVVRVDL-EVPI-GR---GVRIMKLR
E-SIASLICL--
>tr|A0A0C2DPM2|A0A0C2DPM2_9STAP DNA topoisomerase 4 subunit A OS=Salinicoccus roseus GN=parC PE=3 SV=1
KEVLIAKEEVVVSLTSEGYVKRTSLRSYNAST--P---------DD-QVLLS-RHHTLEHLLVFTNLGNYMIIPIHELPE-----NGQHLSNRFRL-GDE
S--TAFVIE----DISIVTTTRRGQIKRTELKAYE----RPISGISLK-DQV-V----E--TEDVLLITQKGISL------V--VGLKAQGVRAIQLK--
-DLAFSGLLSN--FLVTVSQRGAVKRTSID------RAQVGSTLL----KIPHRI-GARLIE---DIIL-YSQNTSFKLDA-SIRV---YANGSFVVDEN
F--VARVAFET-
>tr|A0A090IYS8|A0A090IYS8_9BACI DNA topoisomerase 4 subunit A OS=Bacillus thermoamylovorans GN=parC PE=3 SV=1
LEVLISSEDVVVTATKEGYLKRTSLRSYAASN--G---------TD-KLIAS-YENTMDVLLIFTNKGNYLYCPIHLLPD-----VGQHVSTIIPI-DSE
Q--SVIPVK----TNYLLFFTKNGMVKKTQLSLYQ----KPLIAIHLK-DEL-L----Q--TKEIFLSSYLGYGL------V--IGVRAAGVKGMNLK--
-DVTGGAVID-NQSIVIATQRGAVKRMAID------RAKRGLVMV----RLPHRA-GFVLAH---TVVITSEKNMTEKISV-ELRM---YSNGSFFMDES
S--VIGIGKLL-
>tr|S0KPK3|S0KPK3_9ENTE DNA gyrase subunit A OS=Enterococcus sulfureus ATCC 49903 GN=gyrA PE=3 SV=1
DEDLIEEEEIVITLTNNGYIKRLANSEFRSQRRGGRGVQGMGV-DEDFVKNLVSCSTHDTLLYFTNAGKVYKSKGYEIPEYGRTAKGIPVINLLGI-DSE
RIQAIVPVS--TEEEYLFFTTRLGVVKRTSVAAFSN-RSNGLIAIGLKENDELVNVL-TKG-NTVIIGTHLGYSVTFTE--VRDMGRMAAGVRGIRLR--
-EVVGSAILREDSEVLVITENGYGKRTASQEYPLKGRGGKGIKTANIT-E-NGPLAGLTTVND-EDILMITNKGVIIRFNVASVSQTGRSTLGVRLMKME
G-KVVTMATVE-
>tr|F8L8Y4|F8L8Y4_SIMNZ DNA gyrase subunit A OS=Simkania negevensis (strain ATCC VR-1471 / Z) GN=gyrA PE=3 SV=1
MEDLIADETVIITISDDDYIKRMPLSTFREQRRGGQGVIGFDT-EHDGLKELYVASTHDYLMSFTNLGRCHWLKVWQIPEAGRRAKGRPLVNMLEGQEGE
HVAAVLRVR-F--DASILLATKRGVVKKTMIDSFSSPRRKGVFAINIDEGDEVISAHVVRKEQQVMLFTREGMAVRFDQ--VRPMGRVARGVRGVKLKA-
-AVVSCEVVKEDETVLVVCEHGYGKRSSVESFRQTHRGGVGVRSI--SK-RNGFVVGALAVGDKDSVVLMSSSGHTLRLGMQDIRVMGRSTQGVKVVNLR
-PVLVAMQKIE-
>tr|A0A0F9JLK2|A0A0F9JLK2_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_1437860 PE=3 SV=1
MEDLIADEQVVIAITDDDYIKRMPTSAFREQRRGGLGVIGIEM-ETDVLKSIYVASTHDYLMIFTSLGKCYWLKVWQIPEAGRRTKGRPLINYIESQKDE
KISTILKVR-F--GTYILLSTLKGVVKKTVVSLYGNIRKKGVNAINVDEGDKLISAHLVHDNDQIMLFTRNGMAVRFDE--VRAVGRVARGVKGVTLKP-
-YVVSTVVVKGTETILVVCENGFGKRSRVDTFRQTNRGGKGVRSI--SK-RNGLVVGALSVQDEDGVFLMSQSGQSLRMRMKDLRVMGRSTQGVKLVALK
-NNLIDMQKIE-
>tr|V2QDI8|V2QDI8_9BACT DNA gyrase subunit A OS=Mucispirillum schaedleri ASF457 GN=gyrA PE=3 SV=1
YEDLIPNDEMVVTITHNGYVKRTLLNNFTAQKRGGKGKIGAAN-NEDFLEEIIYTTNKSHLFIFTTKGKVHFLKVYQIPEQSRDSKGRHISNLL-TDENE
KIASFLTLP---ETKSIFFATKFGVVKRVKTIEFKSG-RSGIIALNLKDNDEIVTTL-TGDNDKIFLATRDGKTIQFSV--VRPMGRTATGVRGILLE--
-DVVSAEVVEE-SPLLAVTSLGYGKGTDKDEYRMQSRGGKGLKLM--TK--TGLVVGVRHIHDEDDIMLITKNGKTIRIAASEVSVIGRNTQGTRLMNTS
-DIVS-FTVVP-
>tr|A0A0G0BN76|A0A0G0BN76_9BACT DNA gyrase subunit A OS=Parcubacteria (Moranbacteria) bacterium GW2011_GWE2_35_2- GN=gyrA PE=3 SV=1
QEDLIADEEAIITLSQDGYIKRMSPTVYRVQKRGG-G--IAT--GD-VIDSVNAVMTHDNLMFFTNTGKVFQTKAYEIPES-RTAKGQAIVNFL-QSE-E
K--EMIAFN--DDYKYLFMATEKGIVKKAKIEDFGN-R-SGLIAINLD--DRLGW---TD---EIIISTANGQSI------VRAMGRTAAGVRGIKLRS-
-GVISMDAVLKGNQLMVFSQNGFGKRSDI-SYK-QKRGGSGIKTA---TTKTGKA-GANIVN-DFDLIITSSQGQIIRIPL-SISV-GR---GVRIMRLK
N-VVASAVI---
>tr|K2EPW6|K2EPW6_9BACT DNA gyrase subunit A OS=uncultured bacterium (gcode 4) GN=gyrA PE=3 SV=1
QEDLIPNEEAIITITEQGYIKRMDPNVYKVQKRGG-G--IAV--ED-GIKKVLAVMTHDDLLFFTDSGKVFQTKAYEIPTS-RIAKGQSIVNFL-QSE-E
T--AIVPFI---NFKYLLMTTELGTVKKTPMEDFAN-R-SGLIAINLA--DMLKW---TD---EIIITTSKGQAI------VRPMGRSAAGVRGIKLRK-
-EVVGMDAVFKGNQLMIITENGFGKRSDL-AYK-QKRGGSGIKTA---TTKTGNV-GANIVN-EEDLILSSGKGQIIRIPL-SVPT-GR---GVRVMKPQ
--KVAATTVL--
>tr|A0A0G0QVI8|A0A0G0QVI8_9BACT DNA gyrase subunit A OS=Parcubacteria (Moranbacteria) bacterium GW2011_GWC2_40_12 GN=gyrA PE=3 SV=1
QEDLIPNEETIIVLTEDDYVKRMPPSLYRVQKRGG-G--IAT--GD-TIDKVVSAMTHDDLFFFTNSGKVFQSKAYEIPVS-RTAKGQAIVNFL-QAG-E
N--AIISTG---EAKYLFMATKSGTVKKSAISDFEK-R-SGLIAINLP--DELRW---TD---EVIITTSGGQAI------VRPMGRGAAGVRGIRLKK-
-DVVGMDVVLKGNQLLVFAQNGFGKRSDL-GYK-QKRGGSGIKTA---TSKTGKV-SAHIVN-ETDLICSSAKGQIIRVPL-SVPA-GR---GVRVMRFN
--KIAATAVL--
>tr|A0A0G0B5N2|A0A0G0B5N2_9BACT DNA gyrase subunit A OS=Parcubacteria (Moranbacteria) bacterium GW2011_GWF1_34_10 GN=gyrA PE=3 SV=1
QEDLVANEESIITLSQSGYVKRMSPDVYKTQKRGG-G--IAN--DD-IISQVYAVMAHDNLLFFTNSGKVFQTKAFEIPET-RTSRGQALVNFL-QSE-E
K--EMVAFN---GFKFFFMATEKGNVKKIKVEEFEN-R-SGLIAIGLD--DKLRW---TD---EIIMATSGGQAI------VRAMGRGAGGVRGVRLKK-
-DVIGVDAVFKGNQLMVVSENGYGKRSDL-LYK-QKRGGSGIKTA---TAKTGKV-GGRIVN-ESDLFVTSTKGQIIRIPL-SISV-GR---GVRIMNMK
--KVGASTII--
>tr|A0A0G1NNS7|A0A0G1NNS7_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWC1_45_14 GN=gyrA PE=3 SV=1
QEDLIPDEEAIITITQDGYIKRMNPDVYKVQKRGG-G--TGT--GD-IIEKVSSVMTHDNLMFFTNSGKVFQTKAYEIPES-RTARGQAIVNFL-QSE-E
K--AMIPFN---AYKYFFMATTSGVVKKSKIDEFDN-R-SGLIAIKLD--DRLNW---TD---EIIISTAQGQAI------VRHMGRTAAGVRGIKLRK-
-DVIGMDAVLKGNQIMIITENGYGKRTDM-HYK-QKRGGSGIKTA---TTKTGKV-GGNVVN-EGDLIVTSIKGQIIRIPL-SIPV-GR---GVRVMRPQ
--KVAAATVL--
>tr|K2FD56|K2FD56_9BACT DNA gyrase subunit A OS=uncultured bacterium (gcode 4) GN=gyrA PE=3 SV=1
QEDLIPNEEAIITITQDGYIKRMNPSAYKVQKRGG-G--MAT--GD-VIEKVSSVSTHDNLMFFTNSGKVFQTKAYEIPES-RTAKGQAVVNFL-QSE-E
K--AMIPYN---IYKFFFMTTTLGVVKKTKLEDFDN-R-SGLIAIGLD--DTLNW---TD---EVIISTAQGQAI------VRPMGRNAAGVRGIKLKG-
-NVVGMDTVAKGNQLLIITSNGFGKRTDL-FYK-QKRGGSGIKTA---TSKTGPV-GGGLLN-EGDFIITSNKGQIIRIPL-SISV-GR---GVRIMKPQ
--QVSAAAIL--
>tr|A0A0G0MIH6|A0A0G0MIH6_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWF2_39_13b GN=gyrA PE=3 SV=1
EEDLVPEEESIITLTEDGYIKRMNPKAYRAQHRGG-G--TMT--ED-DVKYFLSASTHDSILFFTDTGRVFLSKAYEIPAS-RTARGQAIVNIL-QTQ-E
K--AMLPLK--KKEGYLAMATAFGVIKKTPIEDFEN-R-SGLIAVKLQ--DQLGW---SD---EILLSSQAGQVI------IRPMGRAAAGIRGMRLKK-
-GLVGMNIIREDGKLLIVAENGYGKTTDL-HFK-QKRGGSGIKAA---TPKTGKI-AVEVLS-SEDLIAISTKGQVIRTPL-SIPN-GR---GVRIMKMD
A-KVASITCV--
>tr|K1ZQ23|K1ZQ23_9BACT DNA gyrase subunit A OS=uncultured bacterium (gcode 4) GN=gyrA PE=3 SV=1
QEDVIPNEEAIITISQDGYIKRMNPDVYKVQKRGG-G--IAT--GD-FIEKVTSVMAHDNLMFFTNTGKVFQTKAYEIPEA-RTSKGQAVVNFL-QAD-E
K--AMIPYN---GYKFFFMTTTLGVVKKTKIEDFDN-R-SGLIAITLD--DTLNW---TD---EMIISTREGQAI------VRAMGRSAAGVRGIKLKN-
-DVVGMDVVAKGNQLLIITENGYGKRTDL-SYK-QKRGGSGIKTA---TTKIGKV-GANIIN-DGDLFITSLQGQIIRIPL-SISV-GR---GVRIMKPS
--KVAAAAII--
>tr|A0A0G0F6Q8|A0A0G0F6Q8_9BACT DNA gyrase subunit A OS=Parcubacteria (Moranbacteria) bacterium GW2011_GWF1_36_78 GN=gyrA PE=3 SV=1
QEDLVPNEEAIITLSKDGYIKRMNPTVYKVQKRGG-G--IAT--GD-EIQKMLGVMAHDNLLFFTNTGKVFQTKAYEIPET-RIAKGQSIVNFL-SSD-E
S--ALIPFN---NYKYLFMTTQMGTVKKTAISEFEN-R-SGLIAIKLE--DALRW---TD---EVVVTTRNGQAI------VRGMGRTAAGVRGIKLKK-
-DVVGMDIVFKGNQLLVISENGYGKRSDL-FYK-QKRGGSGIKTA---TAKTGKI-GATIIN-DTDLILTSEKGQIIRIPL-SVSV-GR---GVRVMRPQ
--KVSASTVL--
>tr|T0TZ90|T0TZ90_9STRE DNA gyrase subunit A OS=Streptococcus sp. HSISS2 GN=gyrA PE=3 SV=1
DEDLIEEEDVVITLSNKGYIKRLAQDEFRSQKRGGRGVQGTGV-DDDFVRDIVSTSTHDHLYFMTNKGRVYRLKGYEIPEYGRTAKGLPIVNLLKL-DGE
TIQTVINAK--SENNHLVFVTRQGLVKRTKEAEFKN-RQNGLIALKLREGDELINVF-TTG-EEIIIGTKFGYSVRFKE--IRSMGRMAAGVKGVTLR--
-GVVGAAAIMDDQEVLIISEKGYGKRTSATEYPTKGRGGKGIKTANIT-D-NGHLAGIATVSN-EDIMVMTDTGVIIRTAVANISQTGRATQGVKVMRLD
S-RIVTFALVE-
>tr|A0A0B5GWV9|A0A0B5GWV9_9EURY DNA gyrase subunit A OS=Haloarcula sp. CBA1115 GN=gyrA PE=3 SV=1
HEDLIPEEDCVVVITEDDYIKRMPVENFDPQNRGGKGIIGADP-ENDRVSKVFRANSHDYLLCFTNQGQVYRLKTYEIPEMSRTARGKSAINLIDLDDGE
ELTAVVS---F-EDECITMVTRNGYVKRTCCSEFENILSTGIIAAKLEDGDELIDVD-TDGTGDLVIATEAGMTIRFSE--VSEMGRSARGVNGIKLQ--
-DVAAMVATDGRRSLLTVTEHGFGKRTKLDEYRTQSRYGKGLIDI--DR--NGRVSTAKAVTDEDHLVIMSEQGQIMRIRAGDVSQVGRNTKGVTIMGLE
-DRVASVTVVP-
>tr|C7NZR8|C7NZR8_HALMD DNA gyrase subunit A OS=Halomicrobium mukohataei (strain ATCC 700874 / DSM 12286 / JCM 9738 / NCIMB 13541) GN=gyrA PE=3 SV=1
HEDLIPEEDCVVVITEDDYIKRMPVDAFDAQNRGGKGIIGSDP-DGDRVSKVFRANSHDYLLCFTNQGQVYRLKTYEIPEMSRTARGKSAVNII-DGDDE
EITAVVSTD--E-DECLTMVTRNGYVKRTCVDEFENILSTGIIAAKLEDGDALVDVE-TDDSGDLVVATEGGMTIRFDE--VREMGRSARGVRGIDLQ--
-DVAAMVATDDDRALLTVTENGYGKRTLLAEYSKQSRYGKGLIDI--DR--NGRVATAKAVREDDHLVIMSESGQIMRIPAGDVSQVGRNTKGVKIMALD
-VNVASVTVVP-
>tr|A2SQI3|A2SQI3_METLZ DNA gyrase subunit A OS=Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z) GN=gyrA PE=3 SV=1
VMDLIPDEQTLVMLTTQNYIKRVPLDLYRQQKRGGRGVIGMTT-DEDSVDKVFLANTHDYLLCFTNKGRVYWLRVYEIPEGSRTSKGKAIVNLL-NTD-E
EVSAVIPMR---AEKNLLYATKKGRVGKFSQDLFSRPRTGGIIGITLLDGDELVDVV-TDGSTDVVLTTAFGQALRFSE--VRATGRGTQGVIGIRLK--
--VCALTL---TQYLLMITDKGFGKRTEFEEFRGHGRGTQGVKSI--NE--RGKVVSSLAVSDDDQVIITTAGGVVLRTSASDISIQGRGTKGVRVIRVD
-GKVTSVAIVP-
>tr|I7J8J5|I7J8J5_METBM DNA gyrase subunit A OS=Methanoculleus bourgensis (strain ATCC 43281 / DSM 3045 / OCM 15 / MS2) GN=gyrA PE=3 SV=1
KEDLIEDKPMLVSLTSSNYIKRIDLDTYRNQRRGGRGVIGMAT-DDDGVENVFVANMHDYLLCFTDKGRVYWLKVYDLPEGQRTSKGKAVVNLLNLDG-E
RVTTVIPVR----DHYLFFATRGGTVAKMALDEFSR-RQTGINAINLRDGDELVDVK-TDG-KELILTTRFGQSLRFHE--VRAVRRNAMGVRGIKLR--
DTLQAISLVE-NDHLLTITEQGFGKRTEFDEFRGHGRGTMGVRNIVVD-A-GGGVVGSRAVSD-DEIIVMSASGIVIRTKVEEISIQKRNTRGVRIMKLD
-GRVIGFTILD-
>tr|A0A086CGA5|A0A086CGA5_ATETH DNA topoisomerase (ATP-hydrolyzing) OS=Candidatus Atelocyanobacterium thalassa isolate SIO64986 GN=ucyna2_00948 PE=4 SV=1
QSNFVPSKDSILEMTYQGKIAWRMPEDN----------------NN-LLIYSEPIEEREQIIAITDTGKAYPIKVLDIPHI-NI-QSISLIDLLPKNT-K
-NISIFFLA--IKNQNLFLLTNQGKIKRIQISELNV-T-RGLSLMKLK--DYLKY---K----EIIIAISSGRLL------IPIMNRNTQGDQ-FRLR--
-KIVGCINLNK--KILLVSKLGYGKYLDI-DLR-TKLGDIGTQAL--IQS---DL-GIKIVSN---INILTNQNRALTLEI-EFQN------NKQTVELF
E-GIIHIN----
>tr|D3ENJ2|D3ENJ2_ATETH DNA topoisomerase (ATP-hydrolyzing) OS=Atelocyanobacterium thalassa (isolate ALOHA) GN=UCYN_02980 PE=4 SV=1
QLNLNLSKDSILEMTYQGEVAWRKPEDR----------------NK-LLIYSEIIGEREQIIVITDNGKAYPIKILDIPYI-DV-QSTFLISLLPENT-K
-SVSIFFLT--VENRNLLLLTNQGKIKRIQLSELNS-T-RGLSLMKLK--DFLKY---K----EIVIAITSGRLL------IPVMNRNTQGEQ-FRLR--
-KIVGCINMNK--DILLVSKLGYGKRLNV-DLR-TKLGDIGTQAL--IQA---DL-GIKVSSN---INILTNKNRVITTEI-EVEN------NKPIVELF
T-IIIHIN----
>tr|A0A0G0FNJ6|A0A0G0FNJ6_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWB1_35_5 GN=gyrA PE=3 SV=1
VEDLIADEENTLILTAGGYVKRTSPDEYKKQKRGG-G--ILD--ED-FVINFLTANTHSDLIFFTDLGKAYQIKMYELPEK-RATRGKSIMNFI-SSG-E
R--SILPMPED-KDLSLMMITEGGIGKKVSASSFHD-R-NGIIAIKLG--DKLIS---V---DSGIVVTSKGQSI------VREMGRTAAGVRIIKLKG-
-KVIGAHAIPKDAALLTLGTNGYGKKTII-EYK-QKRGGSGIKTS---TAKTGEI-SSTVVT--EEAVAMSKKSQVIRLSL-EIPT-GR---GVRIMKLR
G-SIASFICL--
>tr|A0A0G0PPR0|A0A0G0PPR0_9BACT DNA gyrase subunit A OS=Microgenomates (Woesebacteria) bacterium GW2011_GWA1_39_8 GN=gyrA PE=3 SV=1
MEDIIADEENTLILTAGGYVKRTGPDEYKKQKRGG-G--VLD--ED-FVTNFLTASTHSDLLFFTDRGKAYQIKMYELPEK-RATRGKSIMNFI-SSG-E
R--SILPISEN-KDFSLMMVTEEGTGKKVSASSFHD-R-SGIIAIKLS--DKLIS---V---DSCMVVTSKGQSI------VREMGRTAGGVRVIKLKG-
-RVIGAHPVPKDAALVTMGANGFS-----------------------------------IVT--EEAVAMSKKSQVIRLGL-EIPS-GR---GVRIMKLR
G-SIASFICL--
>tr|A0A094PNG1|A0A094PNG1_9ZZZZ DNA gyrase subunit A OS=freshwater metagenome GN=GM49_1680 PE=3 SV=1
VEDLIPDQSVVVTITKTGYSKRTKADLYRSQRRGGKGVKGA-AKQDDLVEHFFVASTHDWLLFFTNKGRIYRAKVHELPDAGRDARGQHVANLLAFKPDE
TIAQVIAIS---HP-FLAIATRGGIVKKSPLTEYDS-RAGGLIAINLKE-DELVSAA--SEKDEILLVSKNGMSLRFSE--IRSMGRSTSGVIGMKFR-K
-DLLTMAAITDPKFVLTATDGGYAKRTPLDEYRPQGRGGLGVKAAKID-ESRGVLVGAMIVES-DEILAITSGGVVIRTACAEIRE-SRDTLGVRLVNLD
-GSVVSITQVK-
>tr|A0A0R1GW77|A0A0R1GW77_9LACO DNA topoisomerase (ATP-hydrolyzing) subunit A OS=Lactobacillus amylotrophicus DSM 20534 GN=FC62_GL000221 PE=4 SV=1
TSALIAKEDVRVLVSANGYLKRSSLRSYNSTD--A---------DD-QIVFD-DTSTLASLYIFTNKGNLIYRPVHELLD-----TGSHLSQEV-G-LDE
Q--QVFVIL-L-AKKNFLLATDDGYIKQVSLADLQ----KAAVAMKLK-GNKLVH---E--ASELVLFTKFSYAV------V--IGARAAGVKSVNLK--
-DVVDYLLLDPDTKVAMITTRGAFKQFKLS------RAKRGVLTL----RLPHRA-GVVSY--DQELQVTTEQNQVTKFKT-EFPI---YSNGSFIIDAE
D--PVKITKLG-
>tr|A0A0J6EIR9|A0A0J6EIR9_9BACI DNA topoisomerase (ATP-hydrolyzing) OS=Bacillus glycinifermentans GN=ACH95_16070 PE=3 SV=1
DEDLITRENIVVTLTHNGYIKRLPSSTYRSQKRGGKGIQGMGT-EDDFVEHLISTSTHDTLLFFSNKGKVYRAKGYEIPEFGRTAKGIPIINLLEVDK-E
WINAIIPVT---DESYLFFTTKHGISKRTPLSQFAN-RNNGLIALSLRDEDELMAVR-TDG-KQIVIGTRNGLLIRFPE--VRQMGRTAAGVKGITLT--
DDVVGMEILEEDADVLIVTENGYGKRTPASEYRTQSRGGKGLKTCKIT-ENNGPLVTVKATRE-EDLMIITASGVIIRMDINDISVTGRVTQGVRLIRLA
-QHVSTVALVE-
>tr|A0A0R2JPE7|A0A0R2JPE7_9LACO DNA topoisomerase 4 subunit A OS=Lactobacillus lindneri DSM 20690 = JCM 11027 GN=IV52_GL000398 PE=4 SV=1
KKVTVPDEQVIVMVSKDGYLKRSSLRSYKASE--L---------ED-YPVFI-KKSTRDFIYIFTDGGNLIYRPVFEIED-----TGEHISQLN-G-DNE
S--AVFDFP---QSGNFVITTNAGHIKKTEFAKLL----RAAVYEKLK-LQKVVN---E---SEVIIMTEHGLAL------V--SGPKTTGVKSINLG--
-DVINSQIIN--SELGIVFQDGNFKKIKIN------RARKGIKVL----KLPNLA-SFIKIN-DQMLRIYTDHRSAHDVIL-EYHV---TSNGSSAVNTK
D--PVSINHLL-
>tr|A0A0R2BSD2|A0A0R2BSD2_LACSN DNA topoisomerase 4 subunit A OS=Lactobacillus sanfranciscensis DSM 20451 GN=FD36_GL000966 PE=4 SV=1
KKVVVPDEQVMVMVSRDGYLKRSSIRSYKASE--L---------ED-RPVFI-KQSTRDSLFIFTDAGNLVYRPVFELDD-----TGDHISQLS-G-DNE
K--ASFAFP---EQGNFVITTKSGHIKQTEFEKLL----RATVYEKLK-LDSVVD---P---SDILIMTEQGLAL------V--NGARTTGAKAISLS--
-DVVNAQLVN--SPLALVFQNGNFKKIKTN------RARKGVKVL----RLKNLA-NFVRIN-DQILTIYTDHLNGHDVIL-EHGF---TSNGNPEVDVK
D--PVSINHQP-
>tr|W9EGE2|W9EGE2_9LACO DNA topoisomerase 4 subunit A OS=Lactobacillus florum 8D GN=parC PE=3 SV=1
KHVTIPSENVMVLLSHDGYFKRSSLRSFKASD--V---------DD-YPVFI-GQNTQDIVYLFTDRGNLIYRPVNEIDD-----TGSHISQLT-G-DQE
K--AVHTFQ---QSGKFLIASRAGHIKQVQFDKLL----RATSYLKLS-TDAVVS---S--ELQVLLVSQQGLAL------V--TGAKAGGVQSMKLA--
-DVVNCQLVDP-SEVAVIFQDGSFKKLSIS------RGRKGIKIL----HLRILA-DFLMIQ-EQLIQVRTDHDQQLDLVL-KYHV---TSNGTKVLDPK
V--PVRLTHLL-
>tr|A0A0Q9XWZ3|A0A0Q9XWZ3_9BACI DNA gyrase subunit A OS=Virgibacillus soli GN=ACA30_22920 PE=4 SV=1
DEDLIPRENIVVTLTHNGYIKRLPITTYRSQRRGGRGVQGMGT-ENDFVQHLITSSTHDTILFFTNKGKVYRAKGYEIPEFSRTAKGLPIINLLGIEK-E
WINTVICVE---EDWYLFFATKQGVIKRTPVSAFAN-RTSGLIALGLRENDELISVK-TDG-KDIIVGTKNGLLIRFNE--VRSMGRTATGVKGITLA--
DDAVGMEILEEHEDVLVVTKNGFGKRTTAAEYRIQSRGGKGLITCKIT-DRTGTVVAVETVQD-EDIMIITDSGIVIRMDVEDISRIGRNTQGVKLMTLG
-DAVSTVAKVE-
>tr|A0A0B5X0U8|A0A0B5X0U8_BACCO DNA gyrase subunit A OS=Bacillus coagulans DSM 1 = ATCC 7050 GN=gyrA PE=3 SV=1
DEDLIPQESIAITLTHNGYIKRLPISTYRSQKRGGRGVQGMGT-EDDFVEHLLTTSTHDTILFFTNKGKVYKKKGYEIPEYGRTAKGIPIVNLLEIDR-E
WINTMIRVE---EDWFLFFTTKKGISKRTPVTEFAN-RTNGLIAIHLKEEDELISVK-TDG-KEIIIGTKNGMLIRFPE--VRSMGRSATGVKGITLS--
DDVVGMEILEENDDVLIVTKNGYGKRTKGSEYRIQSRGGKGLKTCNIT-NKNGPLIAVKTVTE-EDVMLITAGGVLIRMAVGDISVLGRNTMGVKLIRLG
-EYVATVAKVE-
>tr|A0A0H3XGP6|A0A0H3XGP6_9MOLU DNA gyrase subunit A OS=Spiroplasma atrichopogonis GN=gyrA PE=3 SV=1
PEELIKREEILIMLTKDGYVKRVSNDTFKPQNRGG-G--ILS--ED-VLSKIISANSIDSLLIFTDTGRVYKLRAYQIESS-RQARGIPIINLILIDK-E
N--SILAIN--ESTDNLFFVTKRGIIKKTKLLEFNQ-R-TGKVAIELK--DEVVD---TD---DIIIANSEGKVI------IRAMNRQSVGVKGISNGP-
-SVIGICS---AKYILSITTNGFAKKTLL-EYH-TGRGTKGVKSM---TEKKGDK-FVKSVV--EDILLATKHGNIIRIAL-QIPV-GR---GIKIIKLE
D-VLEA-SELI-
>tr|A0A0C2HZY6|A0A0C2HZY6_9MOLU DNA gyrase subunit A OS=Spiroplasma poulsonii GN=gyrA PE=3 SV=1
PEELIRREDILIMLTQDGYVKRVADDTFKLQNRGGKGITGLAN-MEDSLKKIVGANSIDSLLIFSNFGKVYKLRAYQIETS-RHARGLPIINLIAIDKTE
NIQTILALDI--EQDNLFFVTKKGLIKKTKLSEFNQIRQTGKVAIELKEKDELVSVIITKGTDDVIIGNNIGKVIRFN---IRAMSRQSVGVKGISND--
-VTIGVSSG--AKYVLSVTENGYAKKTPIEDYRLTGRNTKGVKSINLTE-KTGYLKFAQTVV-DEDLLVGTKNGNVIRVSLEQVPL-GRTTSGVKIIRLD
-DKLEVIEILK-
>tr|R4UGY2|R4UGY2_9MOLU DNA gyrase subunit A OS=Spiroplasma chrysopicola DF-1 GN=gyrA PE=3 SV=1
PEELIKQESILILLTKDGYIKRVTEDTFKTQNRGGKGIIGTAN-VDDSINKIVLANSIDSLFFFSNSGKVYKLRAYQVESS-RQARGLPIINLIAIDKKE
QIKTILTINS--QESNLFFVTKKGLIKKTKLAEFSQIRQSGKVAIELKDGDELVDVIVSEDNCDIIIANDDGKVIRFN---IRSMSRQSIGVKGIIND--
-TISISSRL--EEYILSVTENGFAKKTLISEYRVTGRGGKGVKSMNLTY-KTGKLNFVNFVR-DAEIIIATKQGNIIRLPLSQIPT-GRTTSGVKLIKLN
-DKIEVVELLR-
>tr|A0A037UQT6|A0A037UQT6_SPIME DNA gyrase subunit A OS=Spiroplasma melliferum KC3 GN=gyrA PE=3 SV=1
PEELIRREDILIMLTQDGYVKRVSDDTFKLQNRGGKGIIGLAN-IEDSLKKIISANSIDSLLIFSNFGKVYKLRAYNIETS-RHARGLPIINLIAIDKTE
SIQTIIAVDS--TEDNLFFVTKKGLIKKTKISEFNQIRQTGKVAIELKDNDELVSVIITKGYDDVIIGNNIGKVIRFN---IRPMTRQSVGVKGIAND--
-ETIGVSSG--AKYVLSVTENGYAKKTLIKDYRLTGRNTKGVKSMNLTD-KTGYLKFVQTVD-DEDILVGTKKGNIIRVSLEQIPL-GRTTSGVKIMRLE
-DKLEVIEILK-
>tr|A0A0K2JEB3|A0A0K2JEB3_SPIKU DNA gyrase subunit A OS=Spiroplasma kunkelii CR2-3x GN=gyrA PE=3 SV=1
PEELIRREDILIMLTQDGYVKRVADDTFKLQNRGG-G--ILA--ED-SLKKIISANSIDSLLIFSNFGKVYKLRAYQIETS-RHARGLPIINLIAIDT-E
N--TIIAID--STEDNLFFVTKKGLIKKTKISEFNQ-R-TGKVAIELK--DELVS---TD---DVIIGNNIGKVI------IRPMIRQSVGVKGIANNA-
-GTIGVSS---GKYVLSVTENGYAKKTAI-NYR-TGRNTNGVKSI---TDKTGYK-FVQAVN--EDILVGTKKGNIIRFSL-QIPL-GR---GVKIMRLE
D-KLEV-IEIL-
>tr|R5BKE4|R5BKE4_9FIRM DNA gyrase subunit A OS=Veillonella sp. CAG:933 GN=gyrA PE=3 SV=1
VEDLIADEEMVITLTRQGYIKRMNANVYRNQHKGGVGVVGMKT-EDDYVVQISHVRTHNTLLFFTTAGRVYRLKGYEVPESSRNSRGTAIINVLPLNVGE
AVTTMIDME---HDLNLLMVTKQGVVKRTSIEEYQN-RRSGLNAISLADDDRLIAVC-TAG-QDVLLGTRKGMAIRFNE--VRLMKRSAQGVRGIKLN--
-GVVGAGVITE-CQVFTISEEGYGKRNSEDVYSLQKRGGKGTKNFRIT-D-TGDVVAVGIVTS-DEVMLISEQGKIIRFDMKDIAIKGKAISGVKLQNLD
GEKVASVAIIA-
>tr|J4JGG8|J4JGG8_9FIRM DNA gyrase subunit A OS=Veillonella sp. ACP1 GN=gyrA PE=3 SV=1
VEDLIADEEMVITLTKQGYIKRMNANVYRNQHKGGAGVIGMKT-EDDYVTQIMHVRTHNTLLFFTSTGRTYRLKAYEVPEGSRNSRGTAMVNVLPLAVGE
SVTTMIDLE---ENVNLFMVTEFGVVKRTAIEEYRN-RRSGLNAINLDDGDRLISVI-TTG-QDILIGTKLGMAIRCNE--VRLMKRAAHGVRGIKLK--
-GVVGAGVLES-AQVFTISEEGYGKRNEADAYNVQKRGGIGTKNFRIN-D-TGDVVAVEVVHD-DEVMLISEQGKIIRFNMNDIAVKGKAISGVKTQNLD
EGKVASIAVIP-
>tr|A0A096AIT1|A0A096AIT1_9FIRM DNA gyrase subunit A OS=Veillonella montpellierensis DNF00314 GN=gyrA PE=3 SV=1
IEDLIADEEMVITLTKQGYIKRMNANVYRNQHKGGVGVVGIKT-EDDYVAQIMHVRTHNTLLFFTSTGRSYRLKAYEVPESSRNSRGTAMVNVLPLNVGE
QVTTMINLE-VM-DANLFMVTKYGVCKRTKIEEYQNIRRSGLNAINLDEGDRLISVCMTTGGQDILIGTKKGIAIRFN---ARLLKRAAHGVRGINLN--
-EVVGAGVFTGHVQIFTISEEGFAKRNDISAYTLQKRGGKGSKNFRITD-KTGDVVAVEVVR-DDEVMIISEQGKIIRFNTTDIAVKSKAVSGVKTQNLD
SGKVASITVIP-
>tr|F9N614|F9N614_9FIRM DNA gyrase subunit A OS=Veillonella sp. oral taxon 780 str. F0422 GN=gyrA PE=3 SV=1
VEDLIADEEMVITLTRQGYIKRMNANVYRNQHKGGVGVVGMKT-DDDYVAQIMHVRTHNTLLFFTSTGRAYRLKAYEVPESSRNSRGTAIINVLPLNVGE
TVTNMIDLE---SDVNLFMVTKQGVVKRTAIDEYRN-RRGGLNAVALDEGDQLISVG-TYG-QDVLLGTKKGMAIRFHE--VRLMKRAARGVKGINLN--
-GVVGASIIHG-CQVFTISEEGYGKRNVESSYTVQKRGGKGTKNFKIT-E-TGEVVAVEIVNN-DEMMLISEQGKIIRFDVNDIAVKSKAISGVKTQNLD
EGKIASVAVIS-
>tr|Q7NIY2|Q7NIY2_GLOVI DNA topoisomerase (ATP-hydrolyzing) OS=Gloeobacter violaceus (strain PCC 7421) GN=gyrA PE=4 SV=1
LAEITSDDEVVVQLTHRGYVRRIPAAAFERRSRSRR---A-SR-ND-FVVESYPTRTRNELLVITRSGRAYSLKVSEIPEG-PRSRGTPLVTLL-S-G-E
Q--ATFVRE--PPDLFLVLLTREGRIKKLLLSECAN-T-RGLMMLKLS--DQLIQ---T---SQIVVGTSAGRLL------LPAMGRSALGLQAIKLRR-
-GLAAMTVVG-GEDLLMVSRLGLGKRLKT-EIR-QERAGLGTPVG---RERNGDL-AVLAVG-EGEVAMATDQERLVQVDL-ELAA-DR---GKPLAVLN
A-QIIAVTRLS-
>tr|U5QP83|U5QP83_9CYAN DNA topoisomerase (ATP-hydrolyzing) OS=Gloeobacter kilaueensis JS1 GN=gyrA PE=4 SV=1
ADEMVSDDEVVVQFSRRGYVRRLPVATFERSNRARR---S-SR-AD-FVIESYPTRSRNELLAITRSGRAYSLKVGDIPEG-ARARGTPLVTLL-A-N-E
Q--ATFVRE--PSDLYLVLLTREGRIKKLLLSECAN-T-RGLMLLKLG--DQLLQ---T---SQIVVATSAGRLL------LPVMGRTALGLQAIKLRR-
-GLVGMTVAG-QDNLLLLSRQGQAKRLPL-ELR-QERAGLGTPIG---ADRA-DL-ALTSTG-EDELIVVTDQERLIQLRA-DLPV-SR---GRVLPALE
G-QVMALTRLA-
>tr|V4GUC3|V4GUC3_9EURY DNA gyrase subunit A OS=Candidatus Halobonum tyrrellensis G22 GN=gyrA PE=3 SV=1
HEDLIPEEESVVVVTEDDYIKRMPAAEFRAQNRGGKGIIGTDL-EDDRVSSVFLASTHDYLLCFTTHGQVYQLKTYQVPEMGRTARGKSAVNVL-DDDGE
EITAVVNCD--D-EEYLTMVTRDGYVKRTAGEAFDNILSTGIRAIKLEEGDALADVE-THGDHHIVVGTRDGMAIRFAE--VRPMGRSARGVRGVRLT--
-DVAGVAAIDAHNWVLTVTKNGYGKRTDLDEYRVQSRNGKGLIDI--NR--NGPVCAVEAVTHGDHLFALSEGGQILRTPVEGISTYGRNTMGVRVMDLD
-GKVAAVDVLP-
>tr|U1R1B0|U1R1B0_9EURY Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit OS=halophilic archaeon J07HB67 GN=J07HB67_01125 PE=4 S
RADLIPEEEMVVVVTEDDYVKRVPAAEFRAQRRGG-G--I-AN-GD-RVASAFVASTHDTLLCFTDQGQVYQLQTYEVPEG-RTARGTSMVNVL-DDG-E
Q--AVLSCD--TGDSYVTMVTREGYLKRTAGEEFAN-L-TGIRAISLT--DQLAD---N---QDVVIGTADGMAI------ARPMGRAARGVRGIDLAP-
-DVVGLATVADSTWTLTVTANGYGKRTEI-AYR-QSRNGKGLIDI---GDRNGPG-SRRSHP---S--ASVRPGRSHEPPS----R-RR---GT---RWG
------------
>tr|A0A0C2VJW6|A0A0C2VJW6_9PROT DNA gyrase subunit A OS=Sulfurovum sp. AS07-7 GN=gyrA PE=3 SV=1
IEDLIVNEPMVVTITHRGYIKRVPVKQYEKQNRGGKGIAVT-T-DDDFIESFFTCNTHDTLMFVTNLGQLYWLKVYKIPEGSRTAKGKAVVNLINLREDE
KIMAIIPTS---DTKSLALFTKFGIVKRTELSEFSNIRSNGVRAIILDDEDEVITAQ----SKYLMIFTALGQVIRFE---TRTQGRSTRGVRGIKFKD-
-DVVDADVIDCEQEILTVSEMGVGKRTTVDEYRVTNRAGSGVISMKLS--KTGKTVVGNVVD-NQDLMALTSIGKMIRVDMQSIRKAGRNTSGVNIVNVD
--RVVSIARCP-
>tr|A0A0C3A187|A0A0C3A187_9PROT DNA gyrase subunit A OS=Sulfurovum sp. FS08-3 GN=gyrA PE=3 SV=1
IEDLIVNEPMVVTITHRGYIKRVPVKSYEKQRRGGKGTALT-T-EDDFIERFFISNTHDTLMFITNLGQVYWLKVYKIPEGSRTAKGKAVVNLIQLQEDE
KIMAIIPTT---DSKGLVMFTRKGIVKRTNLSEYSNIRNVGVRAINLDEDDEVVEAK----TQWLFVVTKKGLCIRFK---AREIGRVARGVTAIKFKD-
-DVTGAISINNEDEILIVSEKGLGKRTKVSEYREQSRAGKGVIAMKLT--KTGD-VVGVVVE-DQDLMILTSIGKMIRVDMQTIRQAGRNTSGVKVVTTE
--KVVSIAKCP-
>tr|A0A0R1UBV3|A0A0R1UBV3_9LACO DNA topoisomerase (ATP-hydrolyzing) ParC OS=Lactobacillus kalixensis DSM 16043 GN=FC46_GL001694 PE=4 SV=1
EKALVADEQVRVLISRDGYLKRSSLRSYQSTD--S---------SD-KVIYE-KTSTLTNLYLFTNRGNLIYRPVHELVE-----TGQHLSQEI-G-SDE
Q--RVFEID---EEMNFLMATNDGYIKQVQLSNLQ----RAITAMKMK-NSRMLR---K--QAEITLFTNKAYAV------V--SGGKAAGVKSVNLK--
-DVVGYTLVDPLIKVGLVTQRGAFKQFNLN------RAKRGVMVL----RLPHRA-AIVSYG-NHILNLTTSSERHLEVNT-DFPL---YSNGSFIVEPT
D--PVSLELGR-
>tr|I7KQ87|I7KQ87_9LACO DNA topoisomerase 4 subunit A OS=Lactobacillus gigeriorum DSM 23908 = CRBIP 24.85 GN=parC PE=3 SV=1
EKALVADEQVRVLISRDGYLKRSSLRSYQSTS--D---------RD-QVIFE-KDSTLANLYLFTNKGNLIYRPVHELID-----TGQHLSQEI-G-ADE
Q--RVFEIP---DDLTFVLATNDGYIKRLNLSNIQ----RAMSAIKLK-NSTVVR---S--KQEIMLFTQKAYAV------V--SGAKAAGVKSVNLK--
-DIVAYVLADPLLRVGIITNRGAFKQMQLD------RAKRGVLVL----RLPHRA-AIQLYG-DHLLKIMTSSDRKLEVNT-DFPV---YSNGSFIVDTT
D--PVAMILGK-
>tr|A0A0M5JAM5|A0A0M5JAM5_9BACI DNA gyrase subunit A OS=Bacillus gobiensis GN=gyrA PE=3 SV=1
DEDLITQENIVLTLTHNGYIKRLPSSTYRSQKRGGKGIQGMGT-EDDFVEHLISTSTHDTILFFSNKGKVYRAKGYEIPEFGRTAKGIPIINLLEVEK-E
WINAIIPVT---DSSYLFFTTKQGISKRTTLSQFAN-RNNGLIALGLREDDELISVR-TDG-KDIIIGTKDGLLIRFHE--VRQMGRTAAGVKGISLS--
DDVVGMEILEEDSHVLIVTEKGYGKRTPAKDYRVQSRGGKGLKTCKIT-ENNGSLITVKATNE-EDLMIITASGVIIRMDINDISQTGRVTQGVRLIRLG
-QHVATVALVE-
>tr|F2C601|F2C601_STRSA DNA gyrase subunit A OS=Streptococcus sanguinis SK330 GN=gyrA PE=3 SV=1
DEDLIEEADVLITLSNKGYIKRLNQAEFTAQKRGGRGVQGTGV-DDDFVKELVSTSTHDRLLFFTNKGRVYRLKGYEIPEYGRTAKGLPVVNLLKL-DGE
TIQTIINVQ--D-DSYLFFTTRHGVVKRTSVTEFAN-RQNGLKALNLKDEDELINVF-TDG-ADVIIGTKFGYSVRFNE--VRSMSRIATGVRGVNLR--
-GVVGAGVIAEGDEVLVITEKGYGKRTLASEYPTKGRGGKGIKTANIT-D-NGPLAGLMTVTE-EDLMIITNTGVIIRTSVANISQTGRSTMGVKVMRLD
N-QIVTFTSVE-
>tr|H9UC65|H9UC65_FERPD DNA gyrase subunit A OS=Fervidobacterium pennivorans (strain DSM 9078 / Ven5) GN=gyrA PE=3 SV=1
KKDLIPNKDVVMTLTRKGFLKLMDLNAFRTQRRNG-G--TAN--DD-IISQIIYTKLHNKTLFFTSQGKVYEIENIDIEEG-RATKGKPITKYIKL-N-E
R--AMMDI---DYKGDLLFVTKNGVVKRTSLEDFKN-T-KGIRAITFR--DELVS---ES---TVLISTKLGMSI------VRTMGRNAAGVRGIRLR--
-GVVSATILKDSGYILTITEKGFGKLTEA-EYR-QSRDGLGIKNI---VEKTGPV-GVAYVK-DEEVVVFTKDGASIKFKV-DVPS-GR---GVRVIHLA
G-VVADFAVIG-
>tr|B9K9M8|B9K9M8_THENN DNA gyrase subunit A OS=Thermotoga neapolitana (strain ATCC 49049 / DSM 4359 / NS-E) GN=gyrA PE=3 SV=1
VEELIVEEDVVITLSHKGYLKSTPLNSYRSQRRGGKGITV--S-EDDEVEFVVVTKNTSSTLFITNFGKAYVLKNYQIETTGRNTRGKHISAFLNLEDTE
RIVALVPLN----GKDLVIVTKSGKIKRTSLEEFENATSRGVRAIRIEPGDEIVSARSTSEKETLVVATKLGMIIRFPV--VRRMGRNAAGVQAIKLQ--
-EVVSMDVVP--GEILTVTEKGFGKRTPVQLYRVQKRGGTGLRNI--VN-KTGHVVAVRYVKGDEEIVVVTRNGMMIRMPVSEIGVIGRVTKGVKLIELG
-DISKVAV-VK-
>tr|D2C4U8|D2C4U8_THENR DNA gyrase subunit A OS=Thermotoga naphthophila (strain ATCC BAA-489 / DSM 13996 / JCM 10882 / RKU-10) GN=gyrA PE=3 SV=1
EEELIVEEDVVITLSHNGYLKSTPLNSYRSQKRGGKGITV--S-EDDEVEFVVVAKNTASTLFITNLGRAYVLKNYQLETTGRNTRGRHITAFLNLEDTE
KIVALASLN----GNDLVIVTKSGKIKRTALKEFENATSRGVRAIKIEPGDEIVSARVNSEKETLIVATKMGMAVRFPV--VRRMGRNAAGVQAIKLQ--
-EVVSVDVIPP-GEILTVTEKGFGKRTPVQLYRIQRRGGTGLRNI--VN-KTGYVVAVRYVRGDEEIVVVTRNGMMIRFPVSEIGVIGRVTKGVKLIELG
-DISKVAV-VK-
>tr|B7IDD3|B7IDD3_THEAB DNA gyrase subunit A OS=Thermosipho africanus (strain TCF52B) GN=gyrA PE=3 SV=1
ELELIPDKEVVLSLTKKGYLKMMSLDTFKTQRRGG-G--TSN--DD-AIMEIIYTHLHGKTLFFTSYGKVYILNNYQIEES-RTSRGRQIAKYLNI-D-E
K--TMLSV---NFEGELFFVTKNGKAKRTSLKEFEN-N-RGMKAITFD--DLLVS---DQ---TILIATKNGLCI------VRTMGRNAMGVIGIRLS--
-DVVSSSLLMDEHYLLTVTSKGYGKLTET-QYR-QKRGGLGIKNI---ISKAGHV-GVTHVL-NENMMIFTKNGMTLKINL-SLRP-GR---GVKLVNLS
G-EIADFAVIR-
>tr|A6LM89|A6LM89_THEM4 DNA gyrase subunit A OS=Thermosipho melanesiensis (strain DSM 12029 / CIP 104789 / BI429) GN=gyrA PE=3 SV=1
ELELIPDKEVVISLTKKGYLKMMSLSTFRTQKRGG-G--TSS--DD-AIMEIIYTHLHGKTLFFTSKGKVYLLNNYQIEES-RTSKGKHISKYINI-D-E
K--TMLSV---NFVGELFFVTKFGKVKRTSLKDFEN-N-RGLRAINFD--DSLVS---EQ---TILIATKNGMSI------VRTMGRSAMGVTGIKLS--
-DVVSSALLSNENYILTVTSLGYGKLTET-QYR-QKRAGLGIKNI---VSKTGYV-SVSYVL-NEDIMIFTKHGMSIKINI-GLRA-GR---GVKLLNLS
G-KIADIAIIS-
>tr|A8F431|A8F431_PSELT DNA gyrase subunit A OS=Pseudothermotoga lettingae (strain ATCC BAA-301 / DSM 14385 / NBRC 107922 / TMO) GN=gyrA PE=3 SV=1
PEDLIPNEDVVITLTEKGYLKSTSLKDYRSQRRGG-G--VAR--DD-EILTVCTSKMHSQTLFVTSAGKAYILKNYEIELG-RDTKGKPIRAYLNL-D-E
S--TMISF---EWKGDLVLVTKSGRIKRTPLKEFEN-T-RGIRAITFS--DVVVS---SD---QIIIATKNGMAI------VRQMGRSAMGVIGIRLR--
-KVVGMVNVPDNCEILTITVRGFGKRTPV-DYR-QSRGGVGIKTM---VEKAGQC-GIDIVA-KSDVIVMTKNGQSIRFNL-TVSQ-SR---GVKIVDLS
D-EVSHFAVVE-
>tr|F7YV04|F7YV04_9THEM DNA gyrase subunit A OS=Pseudothermotoga thermarum DSM 5069 GN=gyrA PE=3 SV=1
PESYVVDEEIVLTLTQKGYLKATSLRDYRTQRRGG-G--IVK--DD-EITMVCSTRSLAQTLFISSKGKAFVLKNYEIEVG-RDSKGKPIRAYLNL-D-E
I--TMLPF---EWKGDLVLVTKQGKIKRTPLKEFEN-A-RGIKAITFE--DCVVA---YE---QVLMATKNGMAI------VRPMGRAAMGVKGIELR--
-NVVGMVSIPNNCEILTVTTKGFGKRTPV-EYR-QNRGGIGIKTL---VEKVGTA-GVDVVT-QSEVLLMTKNGQSIRLSV-AISV-GR---GVKILELD
D-EVSHFAVIE-
>sp|C5CHA8|GYRA_KOSOT DNA gyrase subunit A OS=Kosmotoga olearia (strain TBF 19.5.1) GN=gyrA PE=3 SV=1
VEDVIPDDEVVVTVTKKGYIKATPLEDYRKQGRGGKGIRGVKT-DADFVTNVVSTTRLSKTVVITSKGKAYFINNYELECTSRSSRGKLLANYVKIEPDE
TVQAVLSVK---ANKHLIITTRKGKIKRTPFEAFINSRTSGIKAITLNEGDSVVDAISTSEEETIIISTRKGMVIRFPI--IRPMGRTAAGVKAMALR--
-EVVSATIVLPERYLFTATERGVGKRTPLSEYRPQHRAGMGVKNI--LE-RTGYVVGSLVVTNEDEIIVITKNGMSIRIPAADIRPTGRVTKGVKVVELR
-DTVASLAVVV-
>tr|A7HL65|A7HL65_FERNB DNA gyrase subunit A OS=Fervidobacterium nodosum (strain ATCC 35602 / DSM 5306 / Rt17-B1) GN=gyrA PE=3 SV=1
KKDLIPNKDIVITLTKKGFLKLMDIDAFRTQRRNG-G--IAN--DD-IISQIIYSKLHSKTLFFTSLGKVYEIENLDIEEN-RGTKGKPINKYIKL-G-E
R--AMVDI---DYVGELFFVTKKGVVKRTSLEDFKN-T-KGIRAITFK--DELVS---NN---TVLISTKLGMSI------VRTMGRNAAGVRGIRLR--
-GVISSTVLENNGYILTITENGYGKLTEV-DYR-QSRDGLGIKNI---IEKTGPV-GVAYVN-DEEIVLFTKDGASIKFKV-DIPT-SR---GVKVMNLA
G-IVADFAVIG-
>tr|K7Z694|K7Z694_BDEBC DNA gyrase subunit A OS=Bdellovibrio bacteriovorus str. Tiberius GN=gyrA PE=3 SV=1
DEDLIADEPMVVTVTNTGLIKRIPVEEYRVQKRGGKGLKGMET-DEDYVTDIFSASTKTMLLVFTDKGKVYWCKVHRLPLGSRTSKGKSLANVVQLSN-E
SVRAILPVN----NKYAVMLTEKGVIKKTSLDAFAN-RTAGIIALTTDLEDGVIDVK-SDG-SDIFIATKEGMSIRFNE--VREMGRTARGVKAITLA--
DVVVAMEVLEKKDTILMVTSKGYGKRSETGEYRIQSRGGVGIITQKTT-D-VGLVIGTKKVAN-MELILSTDKGQVIRMKVTDISVLGRNTQGVRLINID
KDTVTGVAVVA-
>tr|M4V716|M4V716_9DELT DNA gyrase subunit A OS=Bdellovibrio exovorus JSS GN=gyrA PE=3 SV=1
DEDLIADEPMVVTVTNTGYIKRISTEEYRVQKRGGKGLKGMET-EEDYVTDIFTASTKTMLLVFTDKGKVYWCKVHRLPMGTRTSKGKAIANVVQLSP-E
KVRAILPVN----NKNVVMLTEKGIIKKTTLDAFSN-RQAGIIALTTDLDDQVVAVS-SDG-SDIFIATREGMSIRFNE--VRAMGRSARGVKGITLA--
DVVVAMEVLEKPDTILMVTSKGYGKRSEVSEYRVQSRGGVGIITQKTT-D-VGNVVGTKKVSL-HELILSTDQGQVIRMKISDISILGRNTQGVRLINLD
KQFVKGIAVVA-
>tr|K0NV51|K0NV51_9LACO DNA topoisomerase 4 subunit A OS=Lactobacillus equicursoris DSM 19284 = JCM 14600 = CIP 110162 GN=parC PE=3 SV=1
EKALIAEEDVRVLVSRDGYIKRSSMRSYQSTE--S---------TD-RVVYE-GTSTLTNLYLFTNYGNLIYRPVHELTE-----VGQHLSQEL-G-ADE
Q--QVYALE---EDAAFLMATNDGFIKQVALKDLQ----RAIMAMKLK-TSRVIS---K--EREVVLLTNQAFGL------V--IGARAAGVKSINLK--
-DVVACYAFDPLLKLGLVTQRGAFKQMKLD------RAKRGVLVL----RLPHRV-AAKFYG-DHELTLITSSMRKQVIRT-DHPL---QSNGSFVIDVT
D--PRELLLGK-
>tr|F0K264|F0K264_LACD2 DNA topoisomerase 4 subunit A OS=Lactobacillus delbrueckii subsp. bulgaricus (strain 2038) GN=parC PE=3 SV=1
EKALITEESVRVLISRDGYIKRSSMRSFQSTE--A---------TD-RVVYE-GSSTLTNLYLFTNHGNLIYRPVHELVE-----VGQHLSQEL-G-ADE
S--RVFALE---PDLAFLLATNDGFIKQVALADLQ----RAIMAMKMK-DSRVIT---K--KREIILFTNQAFAL------V--VGARAAGVKSINLK--
-DVVACLVTDPLLKVGLVTQRGAFKQMPLK------RAKRGVLVL----RLPHRV-ALKAYG-NHELILITSSLRKQVIRT-DHPV---QSNGSFVIDVK
D--AKELLMGR-
>tr|A0A0R2IV43|A0A0R2IV43_9LACO DNA topoisomerase IV, A subunit OS=Pediococcus parvulus GN=IV85_GL003491 PE=4 SV=1
RKVVVPEEQVMVLVSHDGYLKRSSLRSYNASG--D---------ED-YPIFL-KQSTLDHLMMFTNKGNLISRPVHELTD-----TGEHISQTI-G-GDE
R--KTFAFH-L-ETGEFLIATSDGYIKRTEFSDLT----HAAAFIKLK-ETIVIN---P--EQTVMLISKKGYGL------I--IGARAAGVKSMDLR--
-DVTNVQLVSDVDQVGLITQRGAFKRMAVK------RARRGVLVL----RLPHRV-DFIKLN-SAVLEILTTRGTIHDIIA-EHPL---YSNGSFVIDTE
E--PVSMNLKQ-
>tr|A0A0R2ETL2|A0A0R2ETL2_9LACO ParC protein OS=Pediococcus claussenii GN=IV79_GL001333 PE=4 SV=1
RTVTVADEQVMVLVSHSGYLKRSSLRSYAASG--D---------GD-YPVYQ-RENTLDHLLMFTNKGNLIYRPVHEITD-----TGEHVSQTI-G-QDE
V--KAYSFK-F-DPSYFLIATNDGFIKKTKLADFA----RATTYIKLK-NAKVVN---N--SGTVMLLSHNGYGL------I--NGARAAGVKSMDLR--
-DIVDIALVKENDIVGIVTNRGAFKRMLVS------RARRGVLII----RLPHRA-GFVVIS-TSALEVLTSRGQTHDIIP-EHPL---YSNGTFLIDVD
E--PINIKNKL-
>tr|A0A0R2IVR9|A0A0R2IVR9_9LACO DNA topoisomerase IV, A subunit OS=Pediococcus cellicola GN=IV80_GL000165 PE=4 SV=1
RKVVVPEEQVMVLVSHDGYLKRSSLRSYNASG--D---------ED-YPIFL-KQSTLDHLMMFTNKGNLISRPVHELTD-----TGEHISQTI-G-GDE
R--KTFSFH-L-ESGEFLIATNDGFIKKTSFANLT----HAAVYIKLK-DSIVVN---A--KKTVMLVSEHDYGL------I--IGARTAGVKSMDLR--
-DIANIQLVNDSSEVGLITQRGAFKRMAVA------RARRGILVL----RLPHRV-DFTELV-NAVLEIRTSRELLHDIVA-EHPL---YSNGSFVIDVD
E--PESMVVKP-
>tr|A0A0R2K9F0|A0A0R2K9F0_9LACO DNA topoisomerase IV, A subunit OS=Pediococcus ethanolidurans GN=IV87_GL001870 PE=4 SV=1
RKVVVPEEQVMVLVSHDGYLKRSSLRSYNASG--E---------ED-YPIFQ-EQSTLDHLMMFTNKGNLISRPVHELTD-----TGEHISQTI-G-GDE
R--KTFAFH-L-ENGEFLMATSDGYIKRTEFSNLT----HAAVFIKLK-EAVVVN---P--EQTVMLISKRGYGL------I--IGARTAGVKSMDLR--
-DVTNVQLVNESDQVGLITQRGAFKKMAVK------RARRGILVL----RLPHRV-DFVRLE-HAVLEVRTTRATLHDIIA-EHPL---YSNGSFVIDTD
E--PVSMALKA-
>tr|A0A0F3FYT3|A0A0F3FYT3_9LACO DNA topoisomerase 4 subunit A OS=Pediococcus damnosus LMG 28219 GN=parC PE=3 SV=1
RKVVVPEEQVMVSVSHDGYLKRSSLRSYSASS--E---------ED-YPIFL-KQSTLDHLMMFTNKGNLISRPVHELAD-----TGEHISQTI-G-GKE
R--KAFAFH-L-ENGEFLIATNDGYIKRTDFSNLT----HASTFIKLK-DSVVVN---E--KQTVMLLSERGYGL------I--IGARTAGVKSMDLR--
-DVANIQLVDDSNQVGIITQRGAFKRMAVK------RARRGILVL----RLPHRI-DFIKID-NSILEVRTSRGTLHDIIT-EHPL---YSNGSFVIDVD
E--PVSMMLKP-
>tr|L7ZM65|L7ZM65_9BACI DNA gyrase subunit A OS=Geobacillus sp. GHH01 GN=gyrA PE=3 SV=1
DEDLIPQEHVVITLTHKGYIKRLPLSTYRSQKRGGRGVQGMHT-EDDFVEHLLITSTHDTVLFFTNKGKVYQAKGYEIPEFGRTAKGLPIINLLELDK-E
WINAMIPIE---DERYLVFATKQGIAKRSPLSAFAH-RNNGLIAIHLREGDELISVR-TDG-KHLIIGTKNGMLIRFPE--VRAMGRSATGVKAITLD--
GDVVGMEILEDHHDVLVVTKKGFGKRTPASEYRVQSRGGKGLKTCNVT-DKNGPVVAVTTVVN-EDVMVITTGGVLIRIAVSDISRTGRIAQGVKLIRLS
EHCVATVAKVP-
>tr|D7CQR2|D7CQR2_TRURR DNA gyrase subunit A OS=Truepera radiovictrix (strain DSM 17093 / CIP 108686 / LMG 22925 / RQ-24) GN=gyrA PE=3 SV=1
KEDLIAEEHMVVTLTRGGYIKRTPLAAYRAQARGGRGVNAQKA-EDDINSMLIVGNTHDYLLFFTDRGRVYREKIYDLPEAERAARGSHLRNIL-PAEDE
RVATVLSVR---AEGYFVFATRQGMIKKTAIREYGNLNASGLIAINLIEGDELVSVR-GWDGAHVVLATREGQAIRFPE--VRDTGRATQGVRGIRLK--
-DLVSLSVIAGDAELLAVTECGYGKRTPLSDYPVQGRGGQGVITL--TK--TGPLVSLDYVRGDEELLVLSEGGVLIRTRVGEVSRYGRPSQGVTIMRLG
-GRVVSVMVML-
>tr|F2NLE8|F2NLE8_MARHT DNA gyrase subunit A OS=Marinithermus hydrothermalis (strain DSM 14884 / JCM 11576 / T1) GN=gyrA PE=3 SV=1
PEDLIEDEPMVITMTAAGFLKRTPLEAYRAQGRGGVGVQASRS-DEDEATRLFVANMHDDLLFFTNKGRVYREKVFELPEASRQARGVHIRSIL-PAEDE
EVATLLSVR---IPGHFVFATRRGLIKKTPIREYQNLTASGLIAINLVDGDTLIQVG-AQEDAEVILATRNGQAIRFAL--VRATGRASQGVRGVRLK--
-DVVSLIVVPKTGDLLAVGTRGYGKRTPVEEYPTQGRGGLGVLTF--TK--VGQLAALLAVEGDEDLLVLSRRGLAIRTRVDQVAQYSRATSGVKIMNLQ
-EEIAACFVIR-
>tr|A0A0G1NAQ4|A0A0G1NAQ4_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWC1_45_9 GN=gyrA PE=3 SV=1
DEELIKEEPAIITLSQEDYIRRINPESFRTQKRGG-G--AFE--EEDIPQLVRSCSTHDLLLFFTNTGKLFFVKAYEIPEG-RLGRGKPVNNFL-NSE-E
K--SFIPYH--SQFQYLNLVTKQGLAKKVKLSEILV-R-NGSRVIGLK--DQVVG---SD---NLVLIAKSGQLI------LRAQGKGAKGVKAMTLKK-
-SIVSLGIVSKILRLLVVMGNGFGKMSLI-DFR-QKRGGSGIKSA---NEKTGAV-MAKVIE-EQDLVIVSSSGQTLKLEL-SVPV-GR---GVRLIKLE
D-KVAAAACF--
>tr|M5PVU2|M5PVU2_DESAF DNA gyrase subunit A OS=Desulfovibrio africanus PCS GN=gyrA PE=3 SV=1
IEDLIADEEVVLTLSRRGYIKRTTLDSYQQQKRGGKGISGVLT-DDDFVHTFCSTSNHQYLLLFTNRGRMHQLKVHQVPEGGRYAKGSHIANLL-PDKDE
HVTTALTVR---EHNYFMFVTKRGMIKKTSASLYANVRSSGVRAVNLRDDDELIMVR-INGRDELILVTAEGTSIRFTS--IRPIGRGATGVKGIALR--
-DVVAGVVVRPRRLVLTISEKGYGKRTPVNQYRGQSRGGKGIINM--TK--TGRVVGAVVTYEKEEVILLTSGNKVIRLSSEDISVIGRATQGVRLVRME
-ERVAAFDLIK-
>tr|C4XT13|C4XT13_DESMR DNA gyrase subunit A OS=Desulfovibrio magneticus (strain ATCC 700980 / DSM 13731 / RS-1) GN=gyrA PE=3 SV=1
ILDLIPDEDVVITLSRRGYIKRTKIDNYQQQKRGGKGIAGVAT-GDDFVQSFCATTNHQQLLLFTNLGRMFMLPVHQIPEGQRTAKGAHIANLL-PDKEE
FVATALSIR---EERYFLFVTRKGMVKRTCTDLYKNCRSTGIIAVGLKENDELLTVK-IDDETEVLLATQQGLSNRFHI--VRPTGRGAAGVKGIALK--
-DVAAGVVITSRSEVLTVSANGYGKRTSIEHYPIRNRGGSGVINM--TK--TGQVIGAVMVGDDDELLLLTSANKIIRLSVSGISSVGRATQGVMLVRMD
-NTVMGFDLVD-
>tr|S7TB88|S7TB88_9DELT DNA gyrase subunit A OS=Desulfovibrio alkalitolerans DSM 16529 GN=gyrA PE=3 SV=1
IEDLIADEDVVITFTRRGYIKRVPLDSYQQQRRGGKGIAGTAT-EGDMLHSLLTTSNHQSLLLFTNQGRMHQLKVHRVPEGSRYAKGAHIANLI-PEKDE
YVATALSVR---EDRFFLFVTKRGMVKRTLASLYRNVRSSGIKAVLLRDDDELIMVR-IDQTDEVVLCTREGTAIRFSV--VRPMGRTASGVKGIALR--
-DVMGAVIVPPWGHILTVAERGYGKRTAVGQYRLQSRGGRGVINM--TK--TGKVLGAILVQDDDQLVMMTSANKVIRIGVRDVSVVGRATQGVRLAALD
-GVLAAFDLVR-
>tr|S7U4U7|S7U4U7_9DELT DNA gyrase subunit A OS=Desulfovibrio sp. X2 GN=gyrA PE=3 SV=1
IEDLIADEDVVVTLTRRGYIKRVPLDSYQQQRRGGKGIAGTAT-EGDMLQALLTTSNHQSLLLFTNLGRMHQLKVHRVPEGSRYAKGAHIANLV-PEKDE
HIATAMSVR---EDKYFLFVTKRGMIKRTLAPLYRNVRASGIKAVLLREDDELIMVR-IEHNDEVVLCTQGGTAIRFSV--VRPMGRTASGVKGIALR--
-DVVGAVVVPPWGHILTVSELGYGKRTPVGQYRLQSRGGRGVINM--TK--TGQVRGAILVQDDDQLVMMTSANKVIRIGVKDISVVGRATQGVRLASLD
-GTLAGFDLVR-
>tr|A0A0G1MIW5|A0A0G1MIW5_9BACT DNA gyrase subunit A OS=Parcubacteria (Magasanikbacteria) bacterium GW2011_GWA2_45_39 GN=gyrA PE=3 SV=1
MEDLVPNEETVVVITHDGYIKRLPPDTFKSQARGG-G--IVA--ED-VVEHLFITNTHADILFFTTSGRVFQLKAYDIPQS-RTSKGQAVVNFL-QAQ-E
K--VVLSAP--LTAKFLIMVTVNGLIKKINISDLAQ-R-SGLIAIKLK--DSLQW---SD---DVVLITRQGQSV------VRAMGRTAAGVRGIRLKN-
-NVVGMDAIEENLQLFIISMEGLGKRSPL-QYR-QGRGGSGVKCA---TGKTGEV-AAYVVN-DRDLLMMSMKGQVIRLPF-SVNT-GR---GVRLMRFK
P-KVASVTLI--
>tr|A0A0G0X2M5|A0A0G0X2M5_9BACT DNA topoisomerase (ATP-hydrolyzing) OS=Parcubacteria bacterium GW2011_GWC1_41_7 GN=UU76_C0003G0033 PE=4 SV=1
DEEEIIDENIALLVNQRGFVRTF-----AQDTALS----V----KE-EFGKVYLINTKEKIWAMSRGGRMYQVQSAQFHQEKYLESLLT--------L-D
K--HIFKTFT---DTHLFIVTKNGFGKKLNIQEALS-K-TGTQVIKLQ-D-EVVD---L---NNFFIVTKKGMSL------LGEQGKTARGVKIMNVQK-
-DVLSAGICE--KLLLLAFENGFWKKVDM-EFK-QQRGGRGIKIF--NK--WGVV-AET-IN-DAHVWYAN-GGVAQ-LDV-KLKT-KR---PQPATQSV
S-VL--------
>tr|A0A0F9J5S0|A0A0F9J5S0_9ZZZZ Uncharacterized protein (Fragment) OS=marine sediment metagenome GN=LCGC14_1863530 PE=4 SV=1
QEDFVLEQEVVILLTHDGYVKRIPPDIFRAQGRGG-G--KLN--ED-KMEHLVAASTHDNLLFFTNNGKVFQTRAYEVPKT-RTAKGKLIHSFL-GSK-E
L--ALLRYP--EKDVYLVMATEQGVIKKVALEDFQN-R-NGIIAISLK--DRLRW---A---DEVLLVTRKGQAI------IRAMGRSATGVRGITLK--
DDVTSLDIIEKGMSILVITEKGYGKQTTL-KYK-QRRGGSGIKTA---TNKTGGV-AARLVS-ISEVLAFSANGHIIKTEL-SIRV-GR---GVRVMRLG
G-SVVGIICL--
>tr|A0A0G2BKB8|A0A0G2BKB8_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWB1_56_8 GN=gyrA PE=3 SV=1
EEDLVPQEEAVITLSAGGYVKRLPPNTFHSQRRGG-G--ISE--ED-FLTHFMSVNTHDNMLFFTNRGRVFQIKAYEIPQS-RTSKGKAIHGFL-ESD-E
H--AIVSYR--EKGGHLLMATKNGIVKKTPLQDFQN-R-TGIIAIALK--DALIG---SD---QVMLTTARGQSI------VRSMGRNAAGIKGMRLKG-
-GVAGFDIIRHAERVLVVMANGFAKQTLL-EYK-QNRGGSGIRVA---TEKTGRI-SSQIVS-ETEILALSAKGQVIRTKL-SVRL-GR---GVRIMNLK
S-HLVGVVAI--
>tr|A0A0G1WFH6|A0A0G1WFH6_9BACT DNA gyrase subunit A OS=Parcubacteria (Magasanikbacteria) bacterium GW2011_GWA2_50_22 GN=gyrA PE=3 SV=1
AEDLIPDETTIVMITADGYVKRLPPETFKTQARGG-G--VLT--ED-VVEHLFSTTTHADLLFFTTRGRVFKLKAYEIPQT-RTAKGQALVNFL-EAG-E
K--SVLSLK--GEYKYLVMVTSKGLTKKVDITDFEV-R-SGLIAIKLK--DNLEW---SD---ELMLITAHGQSV------VRAMGRVAAGVRGVRLKG-
-KVVGMDILDTMMELFVIMENGFGKRSNV-LYK-QRRGGSGIKTA---TSKTGEV-GAFIAN-ERDLIMVSKKGQVIRMPF-SVSV-GR---GVRVMRFK
A-RVASVTFI--
>tr|A0A0G1RB67|A0A0G1RB67_9BACT DNA gyrase subunit A OS=Parcubacteria (Magasanikbacteria) bacterium GW2011_GWA2_46_17 GN=gyrA PE=3 SV=1
IEDLVPNESTLVMRTRDGYIKRLPPDTFRQQGRGG-G--VLT--ED-VVDQMIATNTHDDLLFFTNRGRVFQLKAHEIPQS-RTAKGQALVNFL-QAN-E
K--CVISLN--SGFKYLVMVTTKGTIKKVDISAFEN-R-SGLIALKLK--DDLEW---SD---EIMLVSTLGQAI------VRAMGRTAGGVRGMRLKD-
-KIVGMDVVDSALETLVISENGLGKRTAI-EYK-QGRGGSGIKTA---TEKTGRV-SMKVVN-ESDLLLISLKGQTIRLPF-SVPT-GR---GVRVMRFK
E-TVASVTLI--
>tr|R5RPD1|R5RPD1_9FIRM DNA gyrase subunit A OS=Firmicutes bacterium CAG:646 GN=gyrA PE=3 SV=1
IEDLIPNENTVITMTKLGYIKRMTVDNFRNQNRGGKGIKGMQT-QDDYIDELLMTTTHHYLMFFTNMGKVYRLKAYEIPEAGRTARGTAIINLLQLQP-E
KISAVIPIN---DDQYLFMATKKGLVKKTPILDYAN-RKTGLAAISLRDDDELIEVK-ADS-KDIILVTKYGQCIRFDV--VRSTGRVSMGVRGINLG--
-GVIGMQLNTQGDYLLIVSENGMGKRTPMGEFTSQNRGGKGVKCYKIT-E-TGNVVGVKAVNE-NEIMMITTEGIIIRISCSDISILGRITSGVKLMNLD
N-SVASIAKVR-
>tr|A0A078KIJ0|A0A078KIJ0_9GAMM DNA topoisomerase (ATP-hydrolyzing) OS=Candidatus Evansia muelleri GN=gyrA PE=4 SV=1
TQDLIYDEYMVCTIYSSCYAKTQPISILKNKKIGFK-INLLKN-NEDLIQHFLIASKHETIFFFSNKGKLYCLKIYEIPEASKISRGIPIINLLSMNKTE
QITAILSIK---KDSNILLATSLGKVKRINIDKFSRTRSSGLIAIKLDKGDSLISAAITYGNNNIL-ITSYGNLILFDE-SILLMERYTYGMIGISLN--
-DVISLIIPNNTCYILFAYENGFCNFKKIENFYITNMGGQGIISMQISK-RNGLLVSAIQVY-NDKIIIITNKGNIIILKLNESKINSK---GFILISMI
-QKLVTIV----
>tr|U7D827|U7D827_9BACT DNA gyrase subunit A OS=Chitinivibrio alkaliphilus ACht1 GN=gyrA PE=3 SV=1
LEDMIPDEDMVITMSHEGYVKRTSAKTYRTQGRGGRGVKGMDS-DSDFIETMFVASAHSNLLFFTNFGRCYSIKVYAIPETGRQSKGRPLVNII-DLPDE
KIAACIPVK---EEHYIVQTTQKGTINKQSLGAYAKIRRTGINSVNMDEDDRLVSVS-CTNDAYIVIATLQGKAIRVSA--VRPLGRNTRGVRGISLR--
-DVIGTVTLTSEQEILTVTENGFGKRTALSEYRVTNRGGVGIINI--SR--NGSVVSVMAPDPEGDILIITRKGIIIRTEVAHISTTGRNTLGVKLINLA
-DAVIDVTSCT-
>tr|E3CH12|E3CH12_STRDO DNA topoisomerase 4 subunit A OS=Streptococcus downei F0415 GN=parC PE=3 SV=1
TASLIVEEDTYVSLTRSGYLKRTSPRSYNAST--P---------DD-KAVLI-APKTTQHLLIFTNLGNVIYRPVHELTD-----IGEHLSQTLTN-ADE
E--YAEIID----ET-YFAVTKMGQIKRVDRTEFQ----KSSKYAKLK-EDQVVA---K---DAVMVITEKGYAL------V--VGSKAAGVKAINLK--
-DVKAAFIANT-KSFFILTQRGSLKRMALD------RAGRGLQVL----RLPHRF-LAGPVLEQQILEVMSKTGKLEQVNL-DLGL---TSNGSFISDSI
D--VYQAEVK--
>tr|I0ESW0|I0ESW0_HELCM DNA gyrase subunit A OS=Helicobacter cetorum (strain ATCC BAA-540 / MIT 99-5656) GN=gyrA PE=3 SV=1
IEDLIANEPMVVSMSHKGYVKRVDLKVYERQNRGGKGLSGS-T-EDDFIESFFVANTHDILLFITNKGQLYHLKVYKIPEASRTAMGKAIVNLISLAPDE
KIMATLSTK---DERSLAFFTKNGVVKRTNLSEFGSNRSSGIKAINLDEDDELVTAK----SKHLLIASHSGTFIKFP---VREIGRVGRGVRGIRLA--
-DVVGAVVIYDNNKLLSVSENGLGKQTLAESYREQSRGGKGVIGMKLT--KTGNLVGIISDD-NLDLMILTASAKMIRVSIKDIRETGRNASGVKLIDT-
--KVVYVNSCP-
>tr|A0A0G1QD12|A0A0G1QD12_9BACT DNA gyrase subunit A OS=Parcubacteria (Jorgensenbacteria) bacterium GW2011_GWA2_45_9 GN=gyrA PE=3 SV=1
EEDLVPNEETVIMFTLGGYIKRLPPTNFRAQRRGG-G--IFD--ED-FIDRLISANTHDNILFFTDKGKVFQTKVYEIPAS-RTAKGKSIHNYL-EPN-E
S--AIIAYP--HSPRFLVMATKNGVIKKTPIEDFAS-R-TGIIALTLK--DLLRW---SD---EIAMSTSNGQAI------VRQMGRSASGVKGISLKK-
-GVAGLDIIKSNVQLLAVMKRGFAKRTPI-EYK-QKRGGSGIKTA---TEKTGAI-STHVID-IEEILAFSKKGQAIRTSM-DVRI-GR---GVHIMNLD
--ELIGVVCL--
>tr|A0A0G0FRW3|A0A0G0FRW3_9BACT DNA gyrase subunit A OS=Parcubacteria (Wolfebacteria) bacterium GW2011_GWC1_37_10 GN=gyrA PE=3 SV=1
EEDLIPQEEVIITLSSSGYIKRIPPTTFKTQKRGG-G--ISE--ED-FISHFASANTHDNILFFTDKGKVFQTKVYEIPVS-RTAKGKIIQNFL-EPD-E
N--AIISYP---EKKFLVMATQNGTIKKTSLEEFSN-R-SGIIAINLQ--DLLKW---SD---EIFIATGLGQAI------LRPMGRSASGVRAIKLKK-
-DVAGLDIIKKIGNILIVTENGFAKQTAL-QYK-QSRGGSGIKTA---NSKTKKI-AAQLIS--EEILALSAKGQIIKTEI-TIRT-GR---GVRIMKLK
--KIAGIVIL--
>tr|A0A0G1WMR0|A0A0G1WMR0_9BACT DNA gyrase subunit A OS=Parcubacteria (Jorgensenbacteria) bacterium GW2011_GWA1_48_11 GN=gyrA PE=3 SV=1
EEDLIPQEDAVVILTQDGYIKRMAPNSFRAQRRGG-G--IFD--ED-MVHRFAAAQTHDNILFFTDRGKAFQTKVYEIPVT-RTSKGKSIHNFL-EPQ-E
K--TIVTYG--DAKAYLVMATNHGLIKKTPIADFGN-R-TGILALKLK--DLLKW---SS---EVILATALGQAI------VRVMGRGAAGVTAIRLRK-
-GVAGLDIIEEDGRFLILMAKGFAKQTPL-EYK-QKRSGGGIKTA---TDKTGEI-GAHIVA-TEEILAFSSKGQALKTEL-NIRL-GR---GVKIMNLD
A-KLVGLICL--
>tr|A0A0G1W922|A0A0G1W922_9BACT DNA gyrase subunit A OS=Parcubacteria (Jorgensenbacteria) bacterium GW2011_GWB1_50_10 GN=gyrA PE=3 SV=1
EEDLIPEEDVIITLSRGGYIKRLSPTSFRAQKRGG-G--IFE--ED-AIEHLTSASTHDNILFFTDRGRVFQTKVYEIPAS-RTAKGKSIHNFL-EPN-E
K--ALVAYS--SGKSFLVMATSRGLIKRTALSDFTN-R-TGIIAIKLR--DTLRW---SD---QVILVTSGGQAI------ARPLGRSTSGVAAIRLKK-
-NVAGLGIIRGERKLLVVSANGFAKQTPL-EYK-QRRGGGGVKTG---TEKTGPI-SATILE-SVELVAFSSKGQALRTEI-HIRV-SR---GVRIMNLK
I-KLVGIVCL--
>tr|A0A0G0XK66|A0A0G0XK66_9BACT DNA gyrase subunit A OS=Parcubacteria (Wolfebacteria) bacterium GW2011_GWA2_42_10 GN=gyrA PE=3 SV=1
EEDLIPQEEAVISLSAAGYIKRIPPTTFKAQRRGG-G--IGE--ED-LLSHFISADTHDNILFFTDKGKAFQTKVYEIPVS-RTAKGKLIQNFL-EPG-E
N--AIVSYA--ITDNYLVMTTKNGIIKKTSLEDFSN-R-SGIIAINLS--DELKW---SD---EIILTTVFGQAI------LRPTGRTAAGVKAIRLKG-
-GVAGIDIIKKDQRLLVVMENGFAKQTAL-EYK-QSRGGSGIKTA---TSKTGKV-SARIIG-EEELLALSAKGQIIRTKI-SVRI-GR---GVKIMRLK
E-KVAGIVVL--
>tr|A0A0G1L7J5|A0A0G1L7J5_9BACT DNA gyrase subunit A OS=Parcubacteria (Jorgensenbacteria) bacterium GW2011_GWA2_45_13 GN=gyrA PE=3 SV=1
EEDLIPNEEAVITLTRDGYIKRMPPSTFRSQKRGG-G--IFE--ED-MIEQFISAETHDNALFFTDQGRVFQTKVYEIPVS-RTAKGKSIHNYL-EPT-E
R--AVISYS--SLTNFLVMATKDGNIKKTSLSDFAN-R-NGIIAIKLK--DVLRW---SD---EVILSTAFGQAI------IRSMSRAASGVRGINLKK-
-SVAGLDIIRIKLRLLAVMSNGFGKQTQL-EYK-QHRGGSGIKTA---TEKTGQI-AACVID--EEMLAFSKKGQAIKIKL-DVRI-SR---GVRVMNLE
--ALVGIVCS--
>tr|A0A0D0S3C3|A0A0D0S3C3_9BACI DNA gyrase subunit A OS=Anoxybacillus thermarum GN=gyrA PE=3 SV=1
DEDLITRENIVVTLTHRGYIKRLPVSTYRSQRRGGRGIQGMNT-EDDFVEHLVITSTHDIVLFFTNKGKVYKAKGYEIPEFSRTAKGIPIVNLLNIEK-E
VINTVIAID---EDAFLFFTTKQGIAKRSPLSSFAN-RNHGLIAIHLHEGDELISVK-TDG-KHIIVGTKNGMLIRFPE--VRSMGRTAAGVKAITLC--
GDVVGMESLNGNEEILIVTKNGYGKRTPAPEYRIQSRGGKGIKTCNIT-EKNGEVVSVKTVTE-EDLMLMTASGVMIRMAVSDISVMGRNTQGVRLMRLD
EQYVATVAKVP-
>tr|A0A0M1QGL2|A0A0M1QGL2_GEOTC DNA gyrase subunit A OS=Geobacillus thermoglucosidasius (strain C56-YS93) GN=gyrA PE=3 SV=1
DEDLIPRENIVITLTHKGYIKRLPVSTYKSQKRGGRGVQGMHT-EDDFVEHLLITSTHDTVLFFTNKGKVYRAKGYEIPEFGRTAKGIPLINLLELDK-E
WINTIIPID---DNLYLFFTTKQGIAKRSPLSSFAH-RNNGLIAIHLREGDELISAK-TDG-KHIIVGTKNGMLIRFPE--VRAMGRSATGVKAITLE--
GDVVGMEILEDGCDVLVVTKNGYGKRTPASEYRIQSRGGKGIKTCNIT-EKNGPIVAVKTVTE-EDLMLITASGILIRIAVSDISRMGRNTQGVKLIRLS
DHYVATVAKVP-
>tr|A0A0Q3WU80|A0A0Q3WU80_9BACI DNA gyrase subunit A OS=Bacillus shackletonii GN=AN964_20335 PE=4 SV=1
DEDLIPQENIVVTLTHNGYIKRLPISTYRSQKRGGRGVQGMGT-EDDFVEHLLTTSTHDTILFFTNKGKVYRAKGYEIPEYSRTAKGLPIINLLGIEK-E
WINTIIRVE---EDSYLFFTTKKGISKRTPLSDFAN-RTNGLIAIHLREEDELISVK-TDG-KDIIIGTKNGMLIRFPE--VRSMGRTATGVKGITLS--
EDVVGMEILDENNEVLIVTLNGYGKRTPASEYRIQSRGGKGIKTCNIT-EKNGSLVSVKTVTE-EDLMLITAGGVLIRMAVSDISLLGRNTQGVKLIKLG
-DYVATVAKVE-
>tr|R7Q1L7|R7Q1L7_9EURY DNA gyrase subunit A OS=Methanoculleus sp. CAG:1088 GN=gyrA PE=3 SV=1
AEDLIPREDTVYTLSADNYVKRMPLRTYRQQSRGGVGMKGMET-DQDYVKNMFVASSHDYLMFVTNTGRILWLKGYNIPEGSRQAKGKPIVNLLNDQEGE
TITTVIPTP---DDKYLVFCTKNGVLKKTQLSQYGNVRSKGIKAIKLDDDDELVEAA-TDGTDEIVLATNDGQACRFSE--VRPMGRDTRGVRGMTLG--
-NVVSMAVVKSDDLLLTVTEKGMGKTSVVRDYTIHHRGSKGVKTI--TK--SGYVVSVRKVNDGDELMLVSNSGKIIRIQVNSIRQTGRAAQGVKVMELK
-DRVAAVEPVN-
>tr|M4YUS6|M4YUS6_9EURY DNA gyrase subunit A OS=Thermoplasmatales archaeon BRNA1 GN=gyrA PE=3 SV=1
AEDLIPKEETVYTISEDNYVKRLPLRTYKQQNRGGTGMTGLQT-EGDTVRSMFVASSHDYLMFVTNTGRILWLKGYNIPEGSRQAKGKPVVNLLPDQEGE
IVTNVIPTA---EDKCLVFCTRNGLIKKTQLSAYGNVRNKGIKAIRLDDDDELVEVW-SKEGDEIVLASTDGQAIRFPE--VSATGRDTRGVRGMTVG--
-EVISMTVVKPEDMLLTVTENGFGKISIVSDYRLTHRGGKGVITI--TR--NGGVMSVRKVGPEDELMAISSSGKVIRMRVSDIRQTGRNAAGVKIMDLK
-GTIVSVNPVV-
>tr|A0A0Q4BBV9|A0A0Q4BBV9_9EURY DNA gyrase subunit A OS=Methanomassiliicoccales archaeon RumEn M2 GN=AOA81_02360 PE=4 SV=1
EEDLIPREDVVITITGDNYIKRIPLKTYRQQGRGGVGLIGMET-EEDFVTNMFVTSTHDYVMFVTDHGRLHWLKGYRIPEGGRHSKGKPIVNMIADEEGE
NVVSTICAS---DDRFLVFCTKEGIIKKTVLSAFKNVRRKGIKAIKLREDDTLVETH-TDGDDEIIIATHNGLAVRFHE--VGSKGRDTMGVKGVTLN--
-DVVSMSVVKPGDMLLTVSENGYGKISSVDDYRKINRGGKGVITL--TR--NGGVIAVRKVLESDELVVVSTQGKVIRIKVNEIRVTGRNAAGVRIMDLR
-GKVTALQPVA-
>tr|V8TQ46|V8TQ46_9CHLA DNA gyrase subunit A OS=Chlamydia pecorum DBDeUG GN=gyrA PE=3 SV=1
IEDIITDESVIITISGDDYVKRMPIKVFREQRRGGHGVSGFDM-GSDFLKAVYSASTKDYLLIFTNFGQCYWIKVWRLPEGERRSKGKSLINFLEGRPGE
QVAAILNVK-F--D-FLFLATKQGVVKKVPLDAFSNPRKKGIRALEIDDNDELIAACIENEHDRVMLFTKLGMAVRFPH--VRPMGRAARGVRGVSLKQ-
-CVVSCQIVTDNQSVLVVCENGFGKRSLVSDFRETNRGGIGVRSI--NE-RNGDVLGAVPVADNDSILLMSGQGQAIRISMQDVRIMGRSTQGVRLVHLK
-GVLVAMERLP-
>tr|G5GKD9|G5GKD9_9FIRM DNA gyrase subunit A OS=Johnsonella ignava ATCC 51276 GN=gyrA PE=3 SV=1
DEDLIPVEDTVIAMTKLGYIKRMSPDNFKSQNRGGKGIKAMQT-EEDFIEDIIMTNTHKDINFFTNLGKVYRLKAYRIPEG-RTARGNSIVNLLKLDPGE
SVTAIIPNE-N--FKYFIMATRKGMVKKTHISEYENVRANGLTAIALNEDDELIEVKAANGDDHVVLVTKNAKCIVFH---IRITGRKTLGVRGIRLS--
-VVIGMQMKTQGETLLVVSEYGMGKRTSLGEFR-THRGNKGLACYKLTE-KSGCLVGAKLVD-DREIFIITNEGILIRIEVSKIS-IGRVTSGVKLMNID
-EKVAGIAKVR-
>tr|F3B7G8|F3B7G8_9FIRM DNA gyrase subunit A OS=Lachnospiraceae oral taxon 107 str. F0167 GN=gyrA PE=3 SV=1
DEDLIQKEDIIIAMTKLGYIKRMSPDNFNVQNRGGKGIKGMQT-DDDFIEDIVMSTTHKDIYFFTNKGRVYTIKGYKIPEASRTARGIAIVNLLQLQP-E
KISAIIPSE---GEGYLFMVTKKGTIKKCRINLFDN-RKNGLAAINLTEDDELIEVK-THG-DDLIIVSKYGMCIRIND--IRAMGRGATGVRGMRLN--
-AVIGMQLASQGEYLLLVSEYGYGKRTKISEFKVQNRGGKGIICYKDN-D-TGKLVGAKLVND-REILLITTEGIIIRIEVSGISVLGRAATGVKLMNID
EDKIASIAKVR-
>tr|I7JG77|I7JG77_9LACT DNA gyrase subunit A OS=Lactococcus raffinolactis 4877 GN=gyrA PE=3 SV=1
DEDLIEEEDVLITLSNKGYIKRLNQDEFRAQNRGGRGVQGSGV-DEDFIKHMVSTSTHDHLLFFTNRGRVYRMKAYEIPEYGRQAKGLPIVNLLKL-DGE
SIQTVINVE---QERFLLFTTLRGIVKRTSANQFAN-RTNGLKALNLREDDELVNVL-TTG-EELIIGTHDGYSVRFKE--LRDMGRAATGVKGVNLR--
-GVVGSSTINNSQEVLVVSENGLGKRTSAEQYPTKGRGGKGIKVMNVT-E-TGKLAGLVTVND-EDLMLITDTGVIIRTNVDNISQTGRSAQGVKVMRLD
E-HIVTFALVE-
>tr|A0A0C5D2F0|A0A0C5D2F0_9HELI DNA topoisomerase (ATP-hydrolyzing) (Fragment) OS=Helicobacter cholecystus GN=gyrA PE=3 SV=1
VEDLIPNEQVVVTMSHRGYVKRVPLKIYEKQNRGGKGISGN-T-DDDFIESFFVANTHDTIMFITNRGQLYWLKVYKIPEAGRTAIGKAVVNLIQIQQNE
KIMATITTT---EDKSLVFFTKNGIVKRTNLSEYSNIRSVGVRAINLDEDDELVTAK----VQQLFIATYQGMCIRFG---VREIGRVSRGVTGIKFKN-
-DVIGAVTIGSQDKLLTVSELGIGKQTIAGEYRLQSRAGKGVIVMKLT--KTGKLVSVVNND-NMDL---------------------------------
------------
>tr|A0A0C5CL91|A0A0C5CL91_9HELI DNA topoisomerase (ATP-hydrolyzing) (Fragment) OS=Helicobacter mastomyrinus GN=gyrA PE=3 SV=1
IEDLIPNEKVVVTMSHRGYVKRVLLKTYEKQNRGGKGISGN-T-DDDFIESFFVANTHDTIMFVTNKGQLYWLKVYKIPETGRTAIGKAVVNLINLQADE
KIMATITTT---ADKSLVFFTKNGIVKRTNLKEYGNIRSVGVRAINLDENDELVTAH----VKELFIATYKGMCIRFS---LREIGRVSRGVSGIKFKS-
-DVIAATTITSTDKLLTVSERGIGKQTLAGEYRLQSRAGKGVIVQKLT--KTGNLVSVVNND-NVDLMVL------------------------------
------------
>tr|E7G1M6|E7G1M6_9HELI DNA gyrase subunit A OS=Helicobacter suis HS1 GN=gyrA PE=3 SV=1
DEDLIAREDMVVTLSHRGYAKRMPLKIYEQQKRGGKGISGN-T-EDDFIEFFFSANTHDIILFITDKGQLYWLKVYKIPEMGRNAIGKALVNLIDIEPGE
KICAILSTP---PDKFLVFFTKKGMIKRTQLSAFGRVR-IGVRSIELKEGDALVTAQ----NQELFMATAKGMCIRFK---VRDMGRTAMGVIGMRLK--
-DVIGASIALSQHKLLTISSKGMGKQTLIGAYRLQNRGGLGVIGAKLT--KTGNLVAIVH-D-GQDLMLLTKNGKMIRMPMESIRETGRHASGVKLVSVE
--GVVYANTCP-
>tr|Q7MAA9|Q7MAA9_WOLSU DNA gyrase subunit A OS=Wolinella succinogenes (strain ATCC 29543 / DSM 1740 / LMG 7466 / NCTC 11488 / FDC 602W) GN=gyrA PE=3 S
IEDLIPNEPTVVTMSHRGYVKRVPLRSYEKQNRGGKGISGN-T-DDDFIESFFVSNTHDTILFITDKGQLYWLKVYRIPEAGRTAIGKAVVNLIQIGADE
KIMATITTQ---EDKSLMFFTKNGIVKRSNLSEFKNIRSVGIRAINLDDNDELVTAR----VKEIFVATYKGMCIRFP---IREIGRVARGVTGIRFKD-
-DVAGATTIGDKEELLTVSEKGIGKRTEAEEYRLQSRGGKGVIAMKLT--KTGQLVGVVN-D-SMDLMLLTSTGKMIRVDMQTIRKAGRNTSGVIIVNVS
--KVVSIARCP-
>tr|W8GTE3|W8GTE3_9MOLU DNA gyrase subunit A OS=Candidatus Hepatoplasma crinochetorum Av GN=gyrA PE=3 SV=1
DENLIEQKDIIITLSNKGYIKRLEVDEYNLQKRGG-G--RAK--ND-FISTIIFANTHLDLLFFTSFGKVYRLKGYEVRKS-KNAKGIPIVNIIKNHG-E
R--DIVAIK--QK-YDFIFFTKNGLIKKTSADEFTR-N-NGKKALKLT--DRLIG---II---DIIIGNQAGKAV------IRTMGRVTQGVKGIDSS--
-GVVGFATSN-GNLILSISERGFSKLTNL-EYR-TKRAAKGVKTL---IEKAGRI-GLKTVL-NEDLMIIKDDGTIIRTNV-NISQ-GR---GVTTIKLR
E-KITGITIVR-
>tr|A0A0G7ZN70|A0A0G7ZN70_9MOLU DNA gyrase subunit A OS=Candidatus Hepatoplasma crinochetorum GN=gyrA PE=3 SV=1
NESLIENKDIIITLSNKGYIKRLEIDEYNVQKRGG-G--RAK--HD-FISTIIFANTHLDLLFFTSFGKVYRLKGYEIRKS-KNAKGIPIVNIIKNQG-E
K--DMVAIN--HK-YDFIFFTKNGLIKKTSADEFAR-N-SGKKALKLV--DRLIG---II---DIIIGNQAGKAV------VRNMGRVAQGVKGINSS--
-GVCGFATSN-GNLVLSISERGFSKLSDL-EYR-TRRGGKGVKTL---IEKAGRV-GLKAVK-NEDLMIIKSNGTVIRTDV-RISK-KR---GVSTIKIN
D-KITGITIVR-
>tr|E8JNC6|E8JNC6_STREI DNA gyrase subunit A OS=Streptococcus equinus ATCC 9812 GN=gyrA PE=3 SV=1
DEDLIEEEDVLITLSNKGYIKRLAQDEFRAQRRGGRGVQGTGV-DDDFVRELVSTNTHDHVYFMTNKGRVYRLKGYEIPEYGRTAKGLPIVNLLKL-DGE
TVQTIISEK--T-ENYLFFVTRQGVVKRTKESEFSN-RQNGLKALNLKESDELINVI-TNG-DDIIIGTKTGYSVRFNE--VRSMSRSATGVRGVNLR--
-GVVGASRITNDQEVLVITEKGYGKRTLASEYPTKGRGGKGIKTVNIT-K-NGKLAGLVTVND-EDIMVITDTGVMIRTNVADISQTGRATLGVKIMRLD
N-KIMTLALVQ-
>tr|U2J3Y3|U2J3Y3_9STRE DNA gyrase subunit A OS=Streptococcus sobrinus W1703 GN=gyrA PE=3 SV=1
DEDLIEEENVLITLSSKGYIKRLDQDEFRAQKRGGRGVQGTGV-DDDFVKDLVSTSTHDVVLFFTNQGRVYRLKGYEIPEYGRTAKGLPVVNLLKL-TGE
TIQTIISLN--N-EKSLFFTTRQGVVKRTSISEFAN-RQNGLRALNLKEGDELINVL-TTG-DDIIIGTQFGYSVRFRE--VRNMGRGATGVKGITLR--
-GVIGASVITDDQEVLVITEKGYGKRTLASEYPTKGRGGKGIKTANIT-S-NGPLAGLVTVNH-EDIMIMTDTGVIIRTGISNISQTGRSTIGVKVMRLD
N-KIVTLALIE-
>tr|F8D8D4|F8D8D4_HALXS DNA gyrase subunit A OS=Halopiger xanaduensis (strain DSM 18323 / JCM 14033 / SH-6) GN=gyrA PE=3 SV=1
HEDLIPEEEVFVVMTEDDYVKRMPIEDFDPQGRGGKGIIGADV-EGDRVATVFRANTHDYLLCFTNQGKVYQLKTYEIPEMGRTARGKSAVNIL-DDDGE
DITAIVDTD--D-DECVTMVTRNGYVKRTDGEEFDNIRSTGIIASDLEEGDELVDVE-TDGTKDLVIATEGGMTIRFDE--VRAMGRNARGVNGIKLQ--
-DVAGLVATDEDKALLTVTRNGYGKRTRLSEYSRQSRYGKGLIDI--GR--NGPVTAVKAVDDDDQLVLMSEDGQIVRTRVDEVSTVGRNTMGVIVMEVE
-DAVASVDVVP-
>tr|T0JBQ8|T0JBQ8_9HELI DNA gyrase subunit A OS=Sulfurimonas sp. AST-10 GN=gyrA PE=3 SV=1
IEDLIPNEPMVVTITHRGYIKRVPLAQYEKQKRGGKGTAIT-T-EDDFIERFFTCNTHDTLLFVTDRGQLHWLKVYKIPEGSRVAKGKAVVNLLNLMADE
RIRSIIPTT---EEKSLVFFTQKGVVKRTNLSEFSNIRSNGVRAIVLDEDDALITAK----IKYLFIVTKLAQCIKFD---IREQGRSTRGVRGIKFKE-
-DVIDANIIANEQEILVVSEKGIGKRTSAGEYRLTNRGGSGVIAMKMT--KTGKYVVGCLVD-TMDMMALTVAGKMIRVDMQTISKSSRNTSGVYIVK--
--DVASVSRCP-
>tr|A0A0C2V8N6|A0A0C2V8N6_9HELI DNA gyrase subunit A OS=Sulfuricurvum sp. PC08-66 GN=gyrA PE=3 SV=1
IEDLIPNEPMVVTITHRGYIKRVPLANYEKQRRGGKGTAVT-T-EDDFIERFFTANTHDTLLIITDRGQLHWLKVYRIPEGSRTAKGKAVVNLLNLVPDE
KIRSILPTT---ETKSLVFFTEQGIVKRTALSEFSNIRSNGVKAISLDDDDQLVTAK----IKYLFIVTRDAQCIKFD---TRDQGRNTRGVRGIKFKD-
-DVVDANVIKDNEEILTVSEKGIGKRTTAEEYRLTNRGGTGVIAMKLS--KTGKSIVGCLVD-SMDMMALTKSGKMIRVDMQTISKSARNTSGVFIIK--
--DVASVSRCP-
>tr|E0UQ42|E0UQ42_SULAO DNA gyrase subunit A OS=Sulfurimonas autotrophica (strain ATCC BAA-671 / DSM 16294 / JCM 11897 / OK10) GN=gyrA PE=3 SV=1
IEDLIPNEPMVVTITHRGYIKRVPLASYEKQKRGGKGTAVT-T-EDDFIENFFTCNTHDTLLFVTDRGQLHWLKVYRIPEGSRTAKGKAVVNLINLQADE
QIQSIIPTT---EDKSLVFFTKNGIVKRTNLSEFSNIRSNGVRAIVLDDNDALITAK----IKYLFIVTKLAQCIKFE---TREQGRSTRGVRGIKFKE-
-DVVDANIIASDQEILIVAEKGIGKRTDAGEYRLTNRGGSGVIAMKMT--KTGKYIVGCLVD-SMDMMALTKAGKMIRVDMQTISKSSRNTSGVYIVK--
--EVVSISRCP-
>tr|U1WRZ6|U1WRZ6_ANEAE DNA topoisomerase (ATP-hydrolyzing) OS=Aneurinibacillus aneurinilyticus ATCC 12856 GN=HMPREF0083_05842 PE=4 SV=1
-SITVPAEDVIVTITEDQYIKRTSMRSFNSSGASVE---G----GD-AVRYLFKTNTIHQLLLFTSHGQFYQLPVHEIPDR-WKDIGTSLVNVV-SSE-E
K--SAYTID--IMDESFAFVTEGGMVKRTKVEEYSK-QKRGIVAAKVK-D-RIEA---R--NGEFLLVSSGGMAI------VPFTGRNTAGVRGMKL-E-
-EIAGSFVLS-EDVLQIVTKEGVIKRTFV-QFT-QGRGGKGLLVI--RV--QPHV-AAF-LE-QHDLVAKTSAGHM-------------------LPIEW
A---------R-
>tr|R7K5K5|R7K5K5_9FIRM DNA topoisomerase (ATP-hydrolyzing) OS=Subdoligranulum sp. CAG:314 GN=BN603_00653 PE=4 SV=1
ESDEKAVESFVVGLTADGMIKCIPAKNFALSAKDAN---L----AN-LHTELFTALSTSKVMFFSDRGNCYQTTADKLTEK-FRENGMPLKKYF-RCG-E
K--KVFVLGP---KGKLLFYTAQGLVKLTDWSEY-E-L-SAFQAIKLK-D-ALVK---E--DSTVLYVTKGGLCL------IPEQGRVAGGVKGM--MA-
-DLVFAGQIH-GEV-VVVTDKCFSKRVLA-DID-MTRYRKGVKIC--NL--NGNV-WAG-YV-PFDILFMDAAGMLL-LNT-DINI-NR---GKPPKLRK
G-LTF-ATRFV-
>tr|R6GV32|R6GV32_9FIRM DNA topoisomerase (ATP-hydrolyzing) OS=Firmicutes bacterium CAG:552 GN=BN704_00450 PE=4 SV=1
PDEVRENSEYVVA-VNEFYIKKMSVKSFNMANKEFG---S----AE-FDNRILKLKAKDKVCLFTDIGNCHKVNVDSIADR-WKENGERVNRCV-PLN-E
K--F--AV-P---QGDVYFFTLKGMVKKTSWSEY-T-L-SSYQAAKLS-D-KIIS---R--GNDLIFITKSGMCL------IPTQGRISTGVKGI--KA-
-SVVYAGQIT-MFV-NVVTTKGYAKRVPI-GID-IGRYGKGVKII--KG----AV-FAA-VS-VKTVWEFDDDYAMG-VTT-NFPV-VR---GKALV-KN
T-RVY-V--YR-
>tr|R7FUH4|R7FUH4_9PROT DNA topoisomerase (ATP-hydrolyzing) OS=Acidiphilium sp. CAG:727 GN=BN767_00695 PE=4 SV=1
KAASKNNETYIVGVNYNGAVRKVKMSSYKRSAASLT---K----SE-LMRFKVEADDDTLIYTFTDKGNCYRIDAESIPDG-GSSGGVKFDTLA-KIK-E
V--AMFAVRP---QGRLYFFTKQGVVKLTPWAEY-A-A-SSFVAMKLK-D-AVLD---I--NADFMFVTKTGMGL------FSEYKRMSGGIQGM--DY-
-DVVQVTQID-DYDLVVATGLGTFKRVYL-TVN-LPRNRKGVKIA--GD---R-L-GEP-VL-IYLLIEDTDGNTLY-ADS-QFAI-SR---GKPVAA-L
I-AKG-VCSFR-
>tr|R7KDN3|R7KDN3_9FIRM DNA topoisomerase (ATP-hydrolyzing) OS=Acidaminococcus sp. CAG:917 GN=BN810_00670 PE=4 SV=1
LNAGPGYKEGVIAVNPYGEIKFLSFRSYGNGARDIN---S----RE-LVKDVCVVNNTGEVIAFTNFGNYCKINIDEMPEK-WKDSALPLKRVS-ETG-E
K--KVMFI-F---VGELLFYTKKGMIKRSDLSEYLK-A-DYNQAVVLS-D-EVIN---E--DKHVLAVTKKGLSL------VPVQGRKAGGVRGV--KG-
-DVAFMGQCD-GEI-VVCTTAGNAKRIIS-TIE-GNRYLKGSLIA--GA-----I-GIT-LV-PYDFGVVTEDNVVHVVNT-KVKI-TK---GKSIVKGK
K-VAH-KSQYK-
>tr|R6WUP0|R6WUP0_9CLOT DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium sp. CAG:349 GN=BN619_00813 PE=4 SV=1
KSDETAYKEGVVVLSDTGTLKFVGTRGFQQAARRAV---D----NT-TVRKAEFVNNRLKLIAFSNLGNIFKIEIDDLPER-YRDKGISLAELN-KAK-E
Y--QIFTA-P---IGEALIFTKQGMVKRTSFDEL-N-S-SAYKAINLT-D-EVVS---K--GLNVFTATENGMCL------IPVQGRNAGGVKSI--QD-
-SVAFAGLIN-GEI-LVVSETGFAKRVFA-TFD-SKRYRKGVKLI--PG----IV-LAA-YV-PYDIAVFDGENVFG-FST-DVKL-GR---GKQLQKFA
K-ADKHVVDYF-
>tr|R7I9P1|R7I9P1_9FIRM DNA topoisomerase (ATP-hydrolyzing) OS=Faecalibacterium sp. CAG:74 GN=BN770_01749 PE=4 SV=1
EET-AAPEEVIVAFTGAGQLKRMNPALYKKTPLPT------RA-KE-FADFLFMAKTDETLLIFTDHGNCYPLPVASLNEK-PKDRGQLLSGVL-AL--E
K--WMTCIRA-GHLPDILFITRQGMVKRTAAADYDV-S--KFAAVNVK--DRLLT---A---DDLLLFTRSGLCI------VPVQGRVAAGVRCMQVED-
-GVIWCGQLQDSDQIVLLTDRGYAKRLLS-DFE-QNRNGKGVKSF---NKNNGKL-GVVRLE-H-LIRVQQAKSP-AT-LV-NVRL-GK---GMPLVIAV
D-VVTGAELLE-
>tr|R5WHG4|R5WHG4_9DELT DNA topoisomerase (ATP-hydrolyzing) OS=Corallococcus sp. CAG:1435 GN=BN495_00505 PE=4 SV=1
EDDEKPVESVVVALASDYTIKRIPVKNFNLSNKDVL---G----GE-ILTSATECKTDSKVMFFSNYGNCFKTNVGQLPER-FRDKGVVLSQIF-PAG-E
T--AMFILDP---SGEVLTYTRQGMIKRSPWSEY-Q-L-SSFQGYKGK-D-EVFK---Q--GTEIFYVTNRGGCT------IPVQGRIAGGVHCI--NA-
-DVVFAGQVK-GEM-LLVTDKGFMKRLPV-EIT-HARNCKGAKGI---Q--NGSV-FAS-YV-NYQIAIFDRANTYV-VDV-DVSV-NK---GKLPKGKR
G-VEK-VLRFK-
>tr|A0A0G0BC69|A0A0G0BC69_9BACT DNA gyrase subunit A OS=Parcubacteria (Nomurabacteria) bacterium GW2011_GWE1_35_16 GN=gyrA PE=3 SV=1
EEDLIPEKESVLVYTKGGYVKRTDPSEYKNQKRGG-G--VIE--ED-FVTMFVSANTHSDLLFFTNLGKAYQIKMYDIPEK-RATKGKSIMNYM-AVD-E
K--SILPID--KTVEHLMMVTKMGVTKKVSAESFKD-R-SGLIAIKLD--DELEA---V---DDVMLATTLGQSI------VREMGRNAGGVRAMKLGG-
-FVIGVDRIPKALALLTLSSNGLGKKTNI-EYK-QNRGGSGIKTA---TPKTGKI-VAKIV---NEIIAVSQKGQVIRVDL-SIPT-GR---GVTIMKLH
G-SIASIACL--
>tr|A0A0G0SXI7|A0A0G0SXI7_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWC1_40_11 GN=gyrA PE=3 SV=1
DEDLVPEKETMLVLTAGGYVKCTDPSEYHSQKRGG-G--ILE--ED-FVTMLVSGSTHSNLLFFTNLGKVYQMKMYDIPER-RATRGKSIMNFL-SGE-E
K--SILAMP--EGHTSLMLVTKNGTAKKMTSDSFKD-R-SGIIAIRLD--DQLIS---T---DEVMIATGAGQSI------VREMGRTAGGVTGIKLSN-
-EVIGVDVIKNKAAFLTMSANGFGKKTNL-EYK-QKRGGSGVKTA---TSKTGKI-VAKVLT--LELIAMSKKGQVIRTAL-DISS-GR---GVTIMRLR
G-GIASLACI--
>tr|A0A0G0S825|A0A0G0S825_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWA2_40_37 GN=gyrA PE=3 SV=1
DEDLVPEKETILVLTAGGYVKCTDPSEYRAQKRGG-G--ILE--ED-FVTMLVSGSTHSNLLFFTNLGKVYQMKMYEIPEH-RATRGKSIMNFL-SGE-E
K--SILAMP--KTGNSLMLVTKGGIAKKMSSESFKD-R-SGIIAIRLD--DQLIS---T---DEVIIATAEGQSI------IREMGRTAGGVRGIKLSS-
-GVIGVDVVFAKGAFLTMSANGFGKKTDL-EYK-QKRGGSGIKTA---TPKTGKI-VAKVLT--QELIAMSKKGQVIRTAL-DISS-GR---GVTIMRLR
G-GIASLACI--
>tr|A0A0C5CLW5|A0A0C5CLW5_9HELI DNA topoisomerase (ATP-hydrolyzing) (Fragment) OS=Helicobacter muridarum GN=gyrA PE=3 SV=1
IEDLIPNEPVVVTMTHRGYVKKMLLKAYEKQNRGGKGMSAN-T-DDDFIQSFFVANTHDTIMFITNYGQLYWLKVYRIPEASRTAIGKAVVNLINLQDGE
KIMTTITTS---ADKSLAFFTKNGVVKRTNLSEYKNIRNNGIRAINLDSDDSLISAS----VKELFIATKEGQCIRFP---IREIGRVGRGVIGIKFKK-
-DVIAATTIQTEDKLLSISELGIGKQTIAGSYGIINRGGKGVIAMKLT--KTGKLVSVLSND-NKDLMVLTTSGKMIRIPLDSIREAGRNTSGVKIISLG
--KVAFASICN-
>tr|A0A099BAB9|A0A099BAB9_9HELI DNA gyrase subunit A OS=Helicobacter sanguini GN=gyrA PE=3 SV=1
IEDLIPNEEVVVTMSHRGYVKRVLLKTYEKQNRGGKGISGN-T-DDDFIESFFVANTHDTIMFITNRGQLYWLKVYRIPETGRTAIGKAVVNLINLQEGE
KIMTTITTH---DDKSLVFFTKNGIVKRTNLSEYKNVRNNGVRAINLDENDELISAS----VSELFIATREGQCIRFK---IRDIGRVARGVIGIKFKK-
-DVVSASAIKGNDKLLTISELGIGKQTTAAEYRITNRGGVGVIAMKLT--KTGKLITILSND-NMDLMVLTTSGKMIRTPLESIRETGRNASGVKIINLE
SSKVAFASVCN-
>tr|N2BW87|N2BW87_9HELI DNA gyrase subunit A OS=Helicobacter bilis WiWa GN=gyrA PE=3 SV=1
IEDLIPNEAVVVTMSHRGYVKRVLLKTYEKQHRGGKGISGN-T-DDDFIQSFFVANTHDTIMFITNRGQLYWLKVYRIPEAGRTAIGKAVVNLIGLQDGE
KIMTTITTS---EDKSLVFFTKNGIVKRTNLSEYKNIRNNGVRAINLDEDDELISAS----VKELFIATKEGQCIRFA---IRDIGRVARGVIGIKFKA-
-DVIAATTIKGEDKLLSISELGIGKQTLAGSYSTINRGGKGVIAMKLT--KTGKLVSVLSND-NMDLMVLTTSGKMIRVPLESIREAGRNTSGVKIVSLG
--KVAFASICN-
>tr|A0A0G0YV41|A0A0G0YV41_9BACT DNA gyrase subunit A OS=Parcubacteria (Kuenenbacteria) bacterium GW2011_GWA2_42_15 GN=gyrA PE=3 SV=1
QEDLIPDENVIVVITKDGYIKRLAPDTFKTQARGG-G--AVT--ED-TVESLFATTTHKDLLFFTTRGRVFQLKAYEIPVS-RTAKGQAIVNFL-QAG-E
K--AVLSLA---SYKFLVMATRGGTIKKVALDQFDN-R-SGLITIKLK--DVLEW---SD---EIVLTSAVGQAI------LRSMGRTAGGVRGIRLKK-
-NVIGMDVVNTKGFVFALSANGTGKLTSL-NYK-QGRGGSGVKTI---TAKTGQA-SAFIIDPNGDLLIISGKGQVIRLPL-SVPR-GR---GVRLMRLK
A-EVASVTLM--
>tr|A0A0G1KN06|A0A0G1KN06_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWF2_44_17 GN=gyrA PE=3 SV=1
QEDLIPKEAAIIMITKDGYIKRLAPQSFRAQGRGG-G--TLT--ED-IVLHLLSADTHDDILFFTNSGKVFRLKAFEVPES-RTSKGNAVVNFL-EDS-E
S--ALLALD--SQEKFFIMATQNGVIKKVEASEFKN-R-SGLIAINLR--DVLKW---AQ---DIMLGTSRGLAI------LRPIGRNAQGVTGIRLSK-
-GVVGMDIVDKDAYLLSISENGCGKMTRV-EYR-QSRGGKGVKTM---TKKTGET-TSWVVYPNGDLILISKLGQVIRISL-SVPH-GR---GVRLMRLK
K-TVAQVALV--
>tr|A0A0G1V4H3|A0A0G1V4H3_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWA2_48_9 GN=gyrA PE=3 SV=1
QEDLIPNEATVVVVTHDGYVKRLAPETFKRQGRGG-G--ILT--HD-AVEQLVATMTHADLLFFTSRGRVFQLKAYDVPVS-RTAKGQALVNFL-QGD-E
R--SVDSLK--KEYKHLAMVTLKGVIKRVHIEDFTN-R-SGLIAIRLR--DTLQW---TD---DIAITSANGQAI------VRVMGRNASGVRGIRLRK-
-GVAGLAIIEGGEQLLVVMKNGFGKRTNL-SYK-QGRGGSGVKTA---TPKTGAI-AAFTVN-QEDIVIMSDKGQVIRLPL-SVSV-GR---GVRLMRFS
P-GVATVTFV--
>tr|A0A0G1FFD5|A0A0G1FFD5_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWE2_43_12 GN=gyrA PE=3 SV=1
QEDLIPNEAAVVIITHDGYIKRLSPDTFKAQGRGG-G--ILT--AD-AVEHLFSTTTHADLLFFTTRGRVFELKAYDIPPS-RTAKGQAVVNFL-QAE-E
K--EVLTLS--EGYKFLIMVTKHGVIKKVPIDAFAN-R-SGLIAIKLK--DQLHW---AD---EIMLVTSRGQSI------VRPMGRAAAGVRGMKLKS-
-AVTGMDLITEDEQLLVIMAQGYGKRTKL-EYK-QNRGGSGVRTA---TPKTGQV-SAFVVN-KEDLIVMSDKGQVIRLLL-SVSV-GR---GVRIMRFK
S-QVASVTFV--
>tr|A0A0G1QT43|A0A0G1QT43_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWA2_46_9 GN=gyrA PE=3 SV=1
QEDLIPNEPTVVVITHDGYVKRLPPETFRTQSRGG-G--MLT--ED-MVEHFFVTTTHADLLFFTTRGRVFQLKAYEVPAS-RTSKGQAIVNFL-QAG-E
S--SVLPFG---TGRYFVMGTTKGMIKKVSYEHFAN-R-SGLIAMRLK--DALKW---SD---EIMIITKRGQAI------VREMGREASGVRAIRIKS-
-GVVSLSVVPTELELIVVSENGFGKRTKL-QYK-QGRGGSGVKTM---TKKTGEV-GAIIAR-AHDIILISTSGQVIRLPY-SVSV-NR---GVRLMRFR
E-RVASITIVG-
>tr|A0A0G0GKA4|A0A0G0GKA4_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWA2_36_10 GN=gyrA PE=3 SV=1
TEDLIPNETAIITMTHDGYIKRIAPDNFKTQSRGG-G--ILT--ED-EVKFFFATNTHADLMFFTSRGRVFQLKAYEVPAS-RTSKGQNIVNFL-QSE-E
S--SILQSD--NAFKFFVMATKNGLVKRVAVDQFTH-R-SGLIAITLK--DELRW---SD---DVMLVTEKGQSI------VRAMGRSASGVMGIRVKK-
-DLVGVDLIPDDEQLLVVMANGFGKRTNL-EYK-QGRGGSGIKTA---NTKTGFC-TAGIVS-DDDMIIISRKGQVIRLPL-TVSI-GR---GVRLMRFK
T-QVSSVTFI--
>tr|A0A0G1D565|A0A0G1D565_9BACT DNA gyrase subunit A OS=Parcubacteria (Magasanikbacteria) bacterium GW2011_GWA2_42_32 GN=gyrA PE=3 SV=1
SEDLIPNEDTIVMITQDGYIKRLPPDTFKTQHRGG-G--IVT--ED-VVEHLFSTTTHADLLFFTTKGRVFQLKAYEVPQS-RTAKGQAIVNFL-QAD-E
K--AVLSLT---DFKYLVMVTKEGVTKKVDIKDFSN-R-SGLIALKLK--DTLMW---SD---EIMLITSGGQSI------IRAMGRNASGVRGIRLKG-
-SIIGMDIVDPSFQLFIISEEGLGKRTPL-QYR-QGRGGSGIKTA---TKKTGKI-GAYVVN-ERDLMIMSNKGQIIRLPF-TVSV-GR---GVRLMRFK
T-KVASVTLV--
>tr|A0A0R1QCS3|A0A0R1QCS3_9LACO Dna gyrase subunit a OS=Lactobacillus nagelii DSM 13675 GN=FD45_GL002229 PE=4 SV=1
DEDLIEEENVMVVLTHNGYIKRLATSEFKTQHRGGRGIQGMGV-ADDFIEHLISTSTHDELLFFTNLGKVYRMKGYEIPEYSRMAKGIPVINLLGI-DKE
KVQTIINVSQ-QHQSYLFFTTKQGTVKRTVVDEFSN-RKNGLKAITLKDDDELISVL-TND-RNLIIGTHQGYAVSFSE--VRPMGRTASGVRGIRLR--
-NVVGAAILSADSKVFIVSEKGYGKQTSAAEYPIKGRGGKGIKTANVT-A-NGPLIGLTTVQD-EDIMLITDKGVMIRFNIQSVSTTGRATLGVHLIKVA
E-SVATMAKVA-
>tr|A0A0R1UUE9|A0A0R1UUE9_9LACO DNA gyrase subunit A OS=Lactobacillus satsumensis DSM 16230 = JCM 12392 GN=FD50_GL002066 PE=4 SV=1
DEDLIEEEEVAVTLTHNGYIKRLPTSDFKTQRRGGRGIQGMGV-ADDFIEHLVTTSTHDELLFFTNMGKVYRMKGYEIPEYGRTAKGIPVINLLGI-AGE
KIQAVINIS--EQEYYLFFTTKKGITKRTAVAEFAN-RSNGLKAVSLKDNDELINVL-TDG-QNIIIGTHLGYAVSFKE--VRSMGRAATGVRGIRLR--
-AVIGVDVLYPDSHVFVVSENGYGKQTPAKDYPIKGRGGKGIKTSNVT-T-NGPLTGLTTVKD-EDIMLITNKGVMIRFNIQTVSVTGRATLGVHLIRVD
E-LVSTMAKVV-
>tr|A0A0R2C3W5|A0A0R2C3W5_9LACO Dna gyrase subunit a OS=Lactobacillus vini DSM 20605 GN=FD21_GL001618 PE=4 SV=1
DEDLIEEENVVVVLTHNGYIKRLPISEFKTQHRGGRGIQGMGV-DDDFIEHLISTSTHDELLFFTNLGKVYRMKGYEIPEYSRTAKGIPIINLLGI-EKE
KVQTVINVSV--KKCFLFFTTKYGVVKRTLVTEFSN-RKNGLKAITLKDDDELISVL-TND-RKLIIGTHLGYAVSFAE--VRAMGRTASGVRGIRLR--
-NVVGAAILDPESNVFIISEKGYGKQTPAIEYPIKGRGGKGIKTANIT-K-NGPLVGLTTVKD-EDIMLITDKGVMIRFNIQSVSTTGRATLGVHLIKVA
D-SVATMAKVA-
>tr|A0A084HA37|A0A084HA37_9BACI DNA gyrase subunit A OS=Bacillus sp. SJS GN=gyrA PE=3 SV=1
DEDLIPVENIVLTLTHNGYIKRLPISTYRSQKRGGRGIQGMGT-EDDFVDQLLTTSTHDTILYFTNKGKVYRTKGYEVPEYGRTAKGLPIVNLLGVER-E
WVKAIIPVS---DDWYLFFTTKEGISKRTPLSQFAN-RTNGLIALGLREEDELISVR-TDG-KDIIIGTKDGMMIRFPE--VRQMGRTATGVKGINLS--
GDVVGMEILEEDTDILIVTRNGFGKRTPAGEYRIQSRGGKGLKTCNIT-EKNGSVVSFKASTE-EDLMLITANGVLIRMDVNDISTMGRNTQGVRLIRLG
-NHVATVALVE-
>tr|A0A0M2P9K6|A0A0M2P9K6_9BACI DNA gyrase subunit A OS=Bacillus sp. SA1-12 GN=gyrA PE=3 SV=1
DEDLIPVENIVITLTHNGYIKRLPVSTYRTQKRGGRGVQGMGT-DDDFVEQLLTTSTHDTILFFTNKGKVYRAKGYEIPEFSRTAKGLPIINLLSVEK-E
WVNAIIPVS---DDWFLFFTTKEGISKRSPLSQFAN-RNNGLIAVSLREADELISVK-TDG-KDIIIGTKNGMLIRFPE--VRSMGRTATGVKGISLD--
DDVVGMEILDEGVDVLIVTRNGYGKRTPSEEYRIQSRGGKGLKTCNIT-EKNGHVVSVKAATE-EDIMLITASGVIIRMDVATISSMGRNTQGVKLIKLD
-NAVSTVALVE-
>tr|R5N858|R5N858_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:793 GN=gyrA PE=3 SV=1
DEDLIAEEQSIIALTRFGYIKRMPLDTYKSQKRGGKGITGITT-EDDFVKQIFTASTHDIILFFSNKGKLYKLRGFEVPE-GRTAKGTAIVNLLSLDGGE
KITAVIPIK-FE-NQFLLMGTKNGLIKKTPLKEYDSGKKTGLMSINLKEDDELIDVRLTEGENNIVMVTRKGLCITFN---VRPIGRTSQGVLGIRID--
-SVIGMETINAKGTLLAITENGFGKRTELDEYRVQARGGRGVVTYKITS-KTGEIVGIRITG-DDDILMITDTGTVIRIKASEISV-GRNTQGITLMRTS
DGKVVSIEKVN-
>tr|R5YUM6|R5YUM6_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:492 GN=gyrA PE=3 SV=1
VEDLIKEEQTVVALTHFGYIKRMPIDTYRSQKRGGKGITGIST-EEDFVKQIFTASTHDTILFFSNKGKLYRLRGYEIPEG-RTAKGTAIVNLLRLDN-E
KISAVIPIT---DGKYLLMATKNGLIKKTALKDFDS-RKTGLLSITLKDDDELIDVR-TDG-DNVVLVTSKGLSITFDE--VRPVGRSAQGVIGIRLD--
-KVIGMESIIA-ATLLAITEHGFGKRTELSEYRVQNRGGRGVITYKVT-P-TGNIVGIRIAND-EDVMMITDKGTIIRLKVEEISILGRATQGVTLMRTN
GG-VVSIELIQ-
>tr|R6B572|R6B572_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:245 GN=gyrA PE=3 SV=1
EEDLIKEEQMVVALTHFGYIKRMPIDTYRSQKRGGKGISGIST-EEDFVKQIFTTSTHDTVLFFSNKGKLYRLRGYEIPEG-RTAKGTAIVNLLSLDA-E
KISAVIPIS---DSKYLLMATKNGLIKKTPLQEYNS-RKTGLLAITLKDDDELIDVR-TDG-DNVVLVTEKGLCITFDE--VRPVGRSAQGVLGIRLD--
-DVIGMESILS-VTLLAITENGFGKRTELDEYRVQNRGGRGVITYKIT-P-TGNIVGIRMAKD-DDVMLITNSGTIIRINVKDVSILGRATQGVTLMRTN
NE-VVSIETVE-
>tr|C5ZX54|C5ZX54_9HELI DNA gyrase subunit A OS=Helicobacter canadensis MIT 98-5491 GN=gyrA PE=3 SV=1
VEDLIPNEAVVVTMSHRGYVKRVPVRTYEKQNRGGKGISAN-T-DDDFIESFFVSDTHDTIMFITNKGQLYWLKVYKIPEASRTAIGKAVVNLISLAPDE
KIMATITTK---EDKSIAFFTKNGIIKRTNLSEFKNIRSVGVKAINLDGDDELVTAK----IQQILVVTYEGMCVRFG---VREIGRVARGVTAIKFKP-
-DVIGATVVSSNEEILSVSEKGIGKRTEVNEYRITNRGGKGVIAMKLT--KTGKLVGVVN-D-NMDLMVLTSSGKMIRVDMQTIRKAGRATSGVIIVNVD
--KVVSIARCP-
>tr|W0K2C9|W0K2C9_9EURY DNA gyrase subunit A OS=Halobacterium sp. DL1 GN=gyrA PE=3 SV=1
DEDLIPEEDVVVVLSEGDYIKRVPADTFDSQHRGGKGIIGTDL-EDDRVSTVFTASTHDYLLCFTNQGQVYRLKVYQVPEMSRTARGTSAVNIL-DDDGE
EISAVVTAD--ADDEYLTMATRHGYVKRTSVGEFGNILTTGIIATSLEDGDELADVE-TSGDDDVILGSEQGMAIRFDE--VRPMGRNARGVHGMNLE--
-DVAGVAAVDAERTLLTVTEFGYGKRTKLSEYRKQSRNGKGLVDI--DR--NGDVVSLDSVDDDDNLVAMSERGQIIRLPVDEISTYGRNTKGVKVMDVE
-GEVAAVSVYR-
>tr|U2YGR6|U2YGR6_9EURY DNA gyrase subunit A OS=Halarchaeum acidiphilum MH1-52-1 GN=gyrA PE=3 SV=1
DEDLIPEERVVVTLSEGDYIKRTPVETFSTQHRGGKGVIGTDL-EGDRVSTVFTASTHDDLLCFTNQGQVYRLKVYQVPEMSRTARGTSAVNVVDLDDDE
EISAVVTAD---DDEYLTMATRDGYVKRTAVSEFANIRSTGIRAVRLEHGDELVDVEVTDGEGDVIIGTEEGMAIRFDE--ARPMGRSARGVRGVKLD--
-QVAGVAAAGPERDLMTVTEYGYGKRTSLSEYRRQSRNGKGLVDI--GQ-RNGRVASVHSVAAGDEFVAMSEDGQIMRASVSEVSAYGRNTQGVTVMDLA
-HRLAAVDVFT-
>tr|Q9HR29|Q9HR29_HALSA DNA gyrase subunit A OS=Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) GN=gyrA PE=3 SV=1
DEDLIPEEDTVVVLSEGDYIKRVPAETFDAQHRGGKGIIGSDL-DGDRVSTVFTASTHDYLLCFTDQGQVYRLKVYQVPEMSRTARGTSAVNILDLDDGE
EISAVVT---LADDEYLTMATRNGYVKRTSVGEFGNILSTGIIAIDLEDGDALADVE-TDGSHDVILGSEAGMAIRFDE--VRAMGRNARGVRGMDLD--
-DIAGVAAVESDRSLLTVTEFGYGKRTRVGEYRSQSRNGKGLVDI--GR--NGDVVSVDAVGDDDSLVVMSADGQIIQMPVDEISTVGRNTKGVNIMAVG
-GEVAGVSVRA-
>tr|A0A0J1FF90|A0A0J1FF90_9FIRM DNA gyrase subunit A OS=Peptococcaceae bacterium CEB3 GN=gyrA_2 PE=3 SV=1
IEDLIEEEDVVITVTHDGYIKRLPLSTYKSQRRGGKGVHGMTT-EEDFVEHLFITSTHHYLLFFTSRGKMFRLKAYEVPES-RTAKGTAIINLLSINS-E
MITAVLSAK---AEYLIFMATKEGIVKRTRLSEYDS-RRDGLIALNLDEGDELIGVR-TKG-EDIILATAAGLCIRFPE--VREMGRTARGVKGITLA--
-GVVGMDVAGE-GDLLTMTENGYAKRSALTEYRAQGRGGKGLIGMRVT-E-TGRLAGVKVVRE-DELMVITSDGLITRQEVAGISKQGRTAQGVMAMRTD
-G-VVAIAKVV-
>tr|A0A0J1IR24|A0A0J1IR24_9FIRM DNA gyrase subunit A OS=Desulfosporosinus acididurans GN=gyrA_1 PE=3 SV=1
IEDLIAEEEVVVTVTHYGYIKRLPLNTYKSQNRGGKGVHGMAT-EEDFVEHLFITSTHHYILFFTSQGKVYRLKAHEIPES-RTGKGTAIINLLSLSP-E
MITAVMAIK---PDYFLITATKKGIMKKTALQEYDS-RREGLIALTLDEGDELIGVK-TQG-DNILLATRQGIAIRFPE--VRYMGRTARGVKGIKLE--
-TVVGMEVIGD-GELLTMSENGFAKRTDLKEFRVQGRGGKGIIVMKLN-T-TGLLIGVKVVKE-DELMVITNNGIMLRLQVSGISNQGRTAHGVMAMRTG
DS-VVAMAKIV-
>tr|A0A0A2TL61|A0A0A2TL61_9FIRM DNA gyrase subunit A OS=Desulfosporosinus sp. Tol-M GN=gyrA PE=3 SV=1
VEDLIAVEDVVITVTHYGYIKRLPLSTYKSQNRGGKGVHGMAT-ERDFVEHLFITTTHHYILFFTSQGKVYRLKAHEIPES-RIGKGTAVINLLNLSQ-E
MITAVMAIK---SEFFLITATKKGIMKKTALQEYDS-RRDGLIALTLDEGDELIGVK-TQG-DDILLATKNGISIRFAE--VRHMGRTARGVKGISLA--
-NVVGMDVIGD-GELLTMSVNGFAKRTNLKEFRVQGRGGKGIIVMKLN-D-TGSLVGIKVVQE-DQLMVITNDGIMLRIPVASISNQGRSAHGVMAMRTG
-S-VVAIAKVL-
>tr|S7J3V1|S7J3V1_CHLPS DNA gyrase subunit A OS=Chlamydia psittaci 10_1398_11 GN=gyrA PE=3 SV=1
IEDIINDESVIITISGDDYVKRMPIKVFREQRRGGQGVTGFDM-GSDFLKAVYSASTKDYLLIFTNFGQCYWLKVWQLPEGERRAKGKPVINFLEGRPGE
QLAAVLNVK-F--G-FLFLATKKGIVKKVPLTAFSNPRKKGIRALEIDNGDELIAACITSDQERVMLFTKLGMAVRFVH--VRPMGRTARGVRGVSLKE-
-CVVSCQIVTEDQSVLVVCDKGFGKRSQVEDFRETNRGGVGVRSI--NE-RNGDVLGAVPVVDHDSILLMSAQGQAIRINMQDVRIMGRSTQGVRLVHLK
-SVLVAMEKLS-
>tr|I7IYP5|I7IYP5_9LACO DNA gyrase subunit A OS=Lactobacillus pasteurii DSM 23907 = CRBIP 24.76 GN=gyrA PE=3 SV=1
DEDLIEKQDILLTLTHNGYIKRMPITEFKTQNRGGKGIKGMGV-DGDFTEHLIYSSTHDMLLLFTNAGKVYSKKAYEIPEYGRTAKGLPIVNLLQL-DGE
KIQTVINIP---DDNYLFFITKMGVVKRTHVSEFAN-RNSGLIALSLRDGDELSNVL-TDG-QNILIGTHLGYAVTFSE--VRPMGRTATGVRGINLR--
-NVIGSDVIKPDDEVLVISEKGYGKRTSASEYPIKGRGGKGIKTANIT-E-NGPLAGITIVND-EDLMLITTDGIMIRFKAQNVSQTGRSTLGVRLIKVE
D-QVASLATVP-
>tr|A0A0R1XYF2|A0A0R1XYF2_9LACO DNA topoisomerase (ATP-hydrolyzing) subunit A OS=Lactobacillus intestinalis DSM 6629 GN=FC44_GL001310 PE=4 SV=1
DEDLIERQNVLLTLTHSGYIKRMPINEFKTQNRGGKGIKGMGV-DGDFTEHLIYSSTHDMLLFFTNKGKVYSKKAYEIPEYGRTAKGLPIINLLQL-EGE
KIQTVINIP---DDNYLFFITKMGTVKRTHVGEFSN-RNSGLIALTLRDGDELSNVL-TDG-QNILIGTHLGYAVTFNE--VRPMGRTAAGVRGINLR--
-HVVGSEVIKPNDDVLVISEKGYGKRTSASEYPIKGRGGKGIKTSNVT-E-NGPLAGVTVIDT-NDIMVITTDGIMIRFKTDDVSQTGRSTMGVRLIKVS
D-KVASLAIVP-
>tr|A0A0F4M6N3|A0A0F4M6N3_9LACO DNA gyrase subunit A OS=Lactobacillus helsingborgensis GN=gyrA PE=3 SV=1
DEDLIEKQDVLLTLTHSGYIKRMPITEFKTQNRGGKGIKGMGV-DGDFIENLIYSSTHDMLLFFTNKGKVYSKKAYEIPEFGRTAKGLPIVNLLQL-EGE
KIQTIVNIP---DDQYLFFITKMGTVKRTHVSEFGN-RNSGLIALTLRDGDELNNVL-TDG-QDILIGTHLGYAVRFNE--VRSMGRTAAGVRGINLR--
-NVVGSGVIKNSDEVLVISEKGYGKRTAAAEYPTKGRGGKGIKTANIT-E-NGPLSGVTVIDS-QDIMVITDDGIMIRFKTKDVSQTGRSTLGVRLIKVN
N-KVASLAVVP-
>tr|A0A0R1YDB1|A0A0R1YDB1_9LACO DNA topoisomerase (ATP-hydrolyzing) subunit A OS=Lactobacillus hamsteri DSM 5661 = JCM 6256 GN=FC39_GL000606 PE=4 SV=1
DEDLIEKQNVLLTLTHRGYIKRMPITEFKTQNRGGKGVKGMGV-DDDFTENLIYSSTHDMLLFFTNMGKVYSKKAYEIPEFGRTAKGLPIVNLLQL-DGE
KIQTIINIP---DDNYLFFITKMGTVKRTRVSEFEN-RNSGLIALTLKDGDELNNVL-TDG-QNILIGTHLGYAVTFNE--VRPMGRTAAGVRGINLR--
-NVVGSEVIKPDDEVLVISEKGYGKRTAASEYPIKGRGGKGIKTANIS-E-NGPLAGVTVVDS-KDIMVITTDGIMIRFKIDDVSQTGRNTLGVRLIKVD
D-KVASLATVP-
>tr|V8C8F7|V8C8F7_9HELI DNA gyrase subunit A OS=Helicobacter macacae MIT 99-5501 GN=gyrA PE=3 SV=1
IEDLIPNEPVVVTMSHRGYVKRVLLKTYEKQNRGGKGISGN-T-EDDFIESFFVANTHDTIMFITNRGQLYWLKVYKIPEAGRTAIGKAVVNLINLQADE
KIMATITTS---KDKSLVFFTKNGIIKRTNLSEYSNIRSVGVRAINLDEKDEVVTAR----VKELFIATQKGMCIKFP---AREIGRVARGVTGIRFKK-
-DVIAATTIGSEDKLLTVSERGIGKQTNAGAYRLQSRGGKGVIVMKID-KKTGNLVSVVNND-KLDLMVLTSKGKMIRVDTEAIRESARNTMGVKIVNVA
--KVAFAVTCP-
>tr|A0A0C5D2F6|A0A0C5D2F6_9HELI DNA topoisomerase (ATP-hydrolyzing) (Fragment) OS=Helicobacter pametensis GN=gyrA PE=3 SV=1
IEDLIPNEKVVVTMSHRGYVKRVPLKTYEKQNRGGKGKMSGNT-DDDFIESFFVANAHDTIMFVTNRGQLYWLKVYKIPEAGRTAIGKAVVNLIQIQQ-E
KIMATITTS----NKSLVFFTRNGIVKRTNLSEYSN-RSVGVRAINLDEDDELVTAK-TSE-KELFIATYEGMCIRFGV--VREIGRVARGVTGIRFKS-
DYVVGAVTIASEDKLLTVSEKGIGKQTTAQSYRLQSRGGKGVIVINST-S-TGKLG--------------------------------------------
------------
>tr|A0A0C5AKS2|A0A0C5AKS2_9HELI DNA topoisomerase (ATP-hydrolyzing) (Fragment) OS=Helicobacter canis GN=gyrA PE=3 SV=1
IEDLIPNEPVVVTMSHRGYVKRVLLKTYEKQHRGGKGISGN-T-EDDFIESFFIANTHDTILFITNKGQLYWLKVYKIPEAGRTAIGKAVVNLINIQPDE
KIMATITTK---SDKSLVFFTKNGIVKRTNLSEYSNIRSVGVRAINLDENDELVSAR----IKELFIATHKGMCIRFS---IREIGRVSRGVTGIRFKK-
-DVIAATTISSNDKLLTVSEQGIGKQTLAGEYRLQSRGGKGVIVMKLT--KTGNLVSIVNND-NMDLMVLTTKGKMIRVDTNAIREAGRNTSGVKIVNVG
--KVAFAVTCP-
>tr|D3UI15|D3UI15_HELM1 DNA gyrase subunit A OS=Helicobacter mustelae (strain ATCC 43772 / LMG 18044 / NCTC 12198 / 12198) GN=gyrA PE=3 SV=1
VEDLIPNEPVVVTMSHRGYVKRVQLKVYEKQNRGGKGISGN-T-DDDFIQSFFVANTHDTILFITNKGQLYWLKVYKIPEAGRTAIGKAVVNLIQLSSDE
KIMATITTS---DDKSLVFFTKNGIVKRTNLSEYSNIRSIGVRAINLDADDELVTAS----VKELFVATYQGMCIRFD---VREIGRAARGVTAIRFKK-
-DVIGATTIRSNDKLLTVSEQGIGKQTLAGAYRLQSRGGKGVIVMKLT--KTGKLVSIINND-NMDLMVLTTSGKMIRVDTEAIREAGRNTSGVKIVNVA
--KVAYASSCP-
>tr|T1CVX9|T1CVX9_9HELI DNA gyrase subunit A OS=Helicobacter fennelliae MRY12-0050 GN=gyrA PE=3 SV=1
IEDLIPNEPVVVTMSHRGYVKRVQLKTYEKQNRGGKGISGN-T-DDDFIESFFVANTHDTIMFITNRGQLYWLKVYKIPEAGRTAIGKAVVNLINLQSDE
KIMATITTT---SDKSLVFFTKNGIVKRTNLSEYSNIRSVGVRAINLDEDDELVTAN----IKELFIATFKGMCIRFG---VREIGRVSRGVTGIRFKK-
-DVIAAVTIGNTDKLLTISEQGIGKQTSAGEYRLQSRGGKGVIVMKLT--KTGNLVSVVNND-NMDLMVLTSSGKMIRVDTEAIRASARNTSGVKIVNVA
--KVAFAVICP-
>tr|A0A0P9HG31|A0A0P9HG31_9CHLR DNA gyrase subunit A OS=Kouleothrix aurantiaca GN=SE17_07850 PE=4 SV=1
DEDLIPDVKVLVTLTERGYVKRINADTYRTQRRGGRGIKGMMT-EQDVVRHILTCMTMDDLLFFTDRGKVYQLKSHEVPDG-RTAKGLPLVNLISLEPGE
QVTSILSVP-F--GEYLIMATQRGKIKRTLLKEYSAVRSNGLIAIGLEDGDMLGWVSMTQGNEDVLITTARGQTIRFR---VRPMGRPASGVIGINLG--
-RVVGMDLVQSNGSLLVVTANGFGKRSAVEEYP-KGRGTGGVITLKLRA--SDEVAAARVVY-TSLLTFITTGGTVMRCLAEEIS-LGRLTQGVTILNLV
-GRVAALSVEE-
>tr|A9WK19|A9WK19_CHLAA DNA gyrase subunit A OS=Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl) GN=gyrA PE=3 SV=1
DEDLIPDVRVMITLTDRGYIKRQLPDAYRTQRRGGRGIKGMLT-EQDIVRHLLTCNSLDNLLFFTDRGKVYQLKAHEVPDS-RTAKGLPLVNLISLEPGE
QVTSMLAVR-F--AEYLVMATVRGKIKRTQLREYSQVRSNGLIAIGLEEGDVLGWVRVSHGHEDILLTTARGQTLRFE---VRPMGRPATGVIGINLA--
-RVVSMDLAEEGADLLVVTARGIGKRTALSEYP-KGRATGGVITIKLRN-DLDEVAAAAVVR-HSLLTFITTGGMVLRTSASEIS-LGRATQGVTIVNVA
-GRVAALSVED-
>tr|A5UR92|A5UR92_ROSS1 DNA gyrase subunit A OS=Roseiflexus sp. (strain RS-1) GN=gyrA PE=3 SV=1
DEDLIPDVRVLITLTDRGYVKRQSPDIYRTQRRGGRGIRGATI-EQDVVRHILAASTMDDLLFFTDRGKVYQIKAHELPDS-RTAKGLPLVNLIALEPGE
QVTSVLAVP-F--AEYLIMATVRGKIKRTSIKEYSQVRSNGLIAIGLEDGDELGWVAMTQGHEDVLLTTARGQTIRFR---VRPMGRPATGVIGIALA--
-RVVSMDLARENAALLVVTANGYGKRTALEEYP-KGRATGGVITIRLRP--GDEVAVAHVVH-HSLLTFITESGMVMRTEADGIS-FGRNTQGVTIVNLA
-NRVAALCVEE-
>tr|A9B0P0|A9B0P0_HERA2 DNA gyrase subunit A OS=Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785) GN=gyrA PE=3 SV=1
TEDLIPDMNVLVTVTDRGYIKKLPGDTYRVQNRGGRGIKGMTT-EDDVVAHLLMCNTLNDLLFFTNRGKVYQLKVHEVPDS-RTAKGLPLVNLISLEPGE
LVTSLIAVP-F--GEYLVMTTVKGRIKRTKLSEYSSVRSNGLIAIGLDTGDELRWVKTSNGDEDILMTTQHGQTIRFS---VRPMGRPASGVIGIKMS--
-QVVGMDLVRPDSQLLVITSHGMGKRTDLEDYP-KGRATQGVITMRLKP--GDIIAAALVLT-SDIVTTITRNGVVMRTRADKIS-YGRTTQGVTVINLD
-KLVAAVSAEP-
>tr|A0A0G1XSX2|A0A0G1XSX2_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWA2_53_21 GN=gyrA PE=3 SV=1
MEDLIPDEPAVIVLTRDGYLKRLPPETFRTQGRGG-G--LLT--ED-AVEHFFATTTHANILFFTSRGRVFQLRSYDVPQS-RTAKGQAVQNFL-EAG-E
R--SVLSAA---RFTYLVMVTKNGTIKKTKLEDFES-R-SGLIAIKLR--DQLEW---TD---EVLLATRAGQTI------IRAMGRNAAGVRGIRMKG-
-KIVGMDVAERAGFLI-VLANGFGKLSPV-DYR-QSRGGSGVKTA---TAKTGEV-AGFVFDGKNDVIMISEKGQVIRLPL-SVPS-GR---GVRLMRFK
A-KVASVTLV--
>tr|L0F3F6|L0F3F6_DESDL DNA gyrase subunit A OS=Desulfitobacterium dichloroeliminans (strain LMG P-21439 / DCA1) GN=gyrA PE=3 SV=1
IEDLIDDEEVVVTMSHRGYIKRIPLSTYKSQRRGGRGVQGMAT-EEDFVEHLFTTTAHQYILFFTTRGKVYRLKAYEIPEG-RTGKGTAIVNLLNINPEE
QITTALCIR---DDFHLFMATKHGIVKKTLLREYNS-RKDGLIAISLHEDDELIGVR-TKA-EHIIMATQKGLCIRFAE--VRQMGRTAHGVKGISLS--
-KVVSMDVIYE-AEILSMTEHGFSKRTNPSEYRVQGRGGKGIIASRLT-E-TGLLVGLKVIVD-DDIMIITDDGIIIRQEVTGISKQGRSAQGVMAMRTG
ESKVVAIAKVA-
>tr|W0E847|W0E847_9FIRM DNA gyrase subunit A OS=Desulfitobacterium metallireducens DSM 15288 GN=gyrA PE=3 SV=1
IEDLIADEDVVITVTHRGYIKRIPLNSYKSQRRGGKGVNGMAT-EEDFVEHLFITSTHQYILFFTSRGKVYRLKAHEIPES-KTAKGIAIVNILNINPEE
EITAILAIK---EDFCLFTATKHGIVKKSALNEYDS-RKDGLIALTLDEGDELIGVR-TRE-DHILMATKNGLSICFNC--VRQMGRTARGVKGINLT--
-DVVGMDVIYE-SELLTMTENGLSKRTDVSEYRVQGRGGKGIIAMKLN-E-TGSLIGIKVVKE-DQLMIITEDGIVIRQDVSGISKQGRSAQGVMAMRTR
-S-VVAIAKVV-
>tr|H5Y125|H5Y125_9FIRM DNA gyrase subunit A OS=Desulfosporosinus youngiae DSM 17734 GN=gyrA PE=3 SV=1
VEDLIAVEDVVVTVTHYGYIKRLPLNTYKSQNRGGKGVHGMAT-EQDFVEHLFTTTTHHYILFFTSQGKVYRLKAYEIPES-RTGKGTAVINLLNLGE-E
MITAVMAIK---PDFFLITATKRGIMKKTALQEYDS-RKDGLIALTLDEGDELIGVK-TQG-DDILLATKHGIAIRFPE--VRYMGRTARGVKGIKLE--
-NVVGMDVIGN-GELLTMSENGFAKRTDLKEFRVQGRGGRGVIVMKLN-A-TGTLVGIKVVQE-DELMVITNNGIMLRIPVSSISNQGRSAQGVLAMRTN
NS-VVAIAKVL-
>tr|Q252J7|Q252J7_DESHY DNA gyrase subunit A OS=Desulfitobacterium hafniense (strain Y51) GN=gyrA PE=3 SV=1
IEDLIDDEEVVITMSHRGYIKRMPLNTYKSQRRGGKGVHGMAT-EEDFVEKIFTTSTHQYILFFTTRGKVYRLKAHEIPEG-RTGKGTALVNLLSINPEE
KITAVLSIR---EDFHLFMATRKGIVKKTLLKEYDS-RKDGLIAISLSGDDELIDVR-TKP-EHIIIATKNGLCIRFLE--VRQMGRTAHGVKGISLE--
-EVVSMDVIYE-AEILSMTELGFSKRTSLSEYRVQGRGGKGIIATKLN-A-TGKLVGLKVMRE-NDMMIITEDGIIIRQEVSGISKQGRSAQGVMAMRTG
ESKVVAIAVVD-
>tr|Q1JZE9|Q1JZE9_DESAC DNA gyrase subunit A OS=Desulfuromonas acetoxidans DSM 684 GN=gyrA PE=3 SV=1
IEDLIVEEDMVVTVSHSGYIKRNAVSLYRSQRRGGKGKTGMRP-EEDFVEKLFIASTHSYILVFTDQGKVYWLKVHEIPQGGRAARGKAIVNLLQLAP-E
RVMTILPVK----DKYIIAATKNGVVKKTELMAYAN-RQGGIISMTIDEGDSLVATR-TDG-MDVLLASHHGKSIRFAE--VRPMGRTARGVRGMQLE--
DTIIGMEVVNDSASLVSVTENGYGKRTNLSEYRVQSRSGKGIITIKTS-D-NGYVVDIKLVTE-EDLMFITDRGKILRTRVGSLSIIGRNTQGVRLMVLE
-DRIVAVAKLA-
>tr|D8P7F0|D8P7F0_9BACT DNA gyrase subunit A OS=Nitrospira defluvii GN=gyrA PE=3 SV=1
LEDLIAEEEVVVTISHAGYIKRNAVTLYRAQRRGGKGKIAMGI-EEDFVETLFTASTHDSLLFFTDAGKVYWLKVHEIPEASRAAKGKALVNLLALSK-E
KVTATLPVK----DRFVIMGTKQGVIKKTELSAYSN-RQGGIIALSLDAGDKLIGVD-TDG-REILLGTKQGITIRFKE--VRAMGRTAHGVRGITLE--
DEVIGMETITPTTAILTVTEGGYGKRTPVNEYRVQGRGGKGIISVKTT-E-NGPAVGFLQVRE-DEIMLMAAQGKVLRCKVDDIREIGRNTQGVRLLDMD
DERVVAVVRLV-
>tr|A0A0M4DEM5|A0A0M4DEM5_9DELT DNA gyrase subunit A OS=Desulfuromonas sp. WTL GN=gyrA PE=3 SV=1
LEDLIVEEDMVVTVSHSGYIKRNAVSLYRAQRRGGKGKTGMRP-EEDFVERLFIASTHSYILVFTDLGKVYWLKVHEIPQGGRASRGKAIVNLLQLST-E
NVTTVLPVK----GKYIITATQNGTVKKTELMSYAN-RAGGIIALTIDEGDRLISAR-TDG-MDILLASRNGKSIRFPE--ARPMGRTARGVRGMMLE--
NHLIGMEVVSESATLVTVTENGYGKRTNLDEYRVQSRGGKGIITIKTS-E-NGKVVDIKLVDD-SDLMFITDRGKVLRTGVAALSIIGRNTQGVRLMVLE
-ERIVAVAKLA-
>tr|K1LR92|K1LR92_9LACT DNA topoisomerase 4 subunit A OS=Facklamia ignava CCUG 37419 GN=parC PE=3 SV=1
ATLLIPEEQVIVSVTNEGYIKRTSRRSFQSSD--T---------MD-YTLFL-EPSTYDTLILLTSHGNYLYIPVHELPD-----MGVHLSQHYQL-EDE
R--SVYRGAQA-ETTAILMLTQQGMIKQTLLKDFV----RSSMAMKLK--DQIVA---Q--QQQILVTTYDSYCV------V--LGLKAQGVIAVNLR--
-DVVSGNTF--TQQFVVLTQRGNIKRFRAD------RAARGLTLL----KLPHRI-DVLAVD--TPVVVQGDTGHFVELTS-EIPL---LTNGSAVQELD
L--VVALHPAN-
>tr|H3NER0|H3NER0_9LACT DNA topoisomerase 4 subunit A OS=Dolosigranulum pigrum ATCC 51524 GN=parC PE=3 SV=1
TEVLVTEEQAIVTVTEQGYLKRTSLRSYAASK--V---------DD-ILLFA-EESTLDHLLIFTNKGNVINRPVHELPD-----VGEHLSRSL-S-AGE
I--AVYSYR---DTAKYVFITRDGYIKQTLENEFE----RSSTAIKLK-ADYVVG---E--HKDIFIATAKGYGL------V--VGANAIGVKSINLK--
-DVVSGIIFERSKEAMVITHRGSVKKLSLA------RANRGLKII----RLPHRQ-YVIDVD-PDPIQLLTDKDKLFAVNP-DYTP---DNNGSFILNTD
D--IT---GYR-
>tr|H3NKL9|H3NKL9_9LACT DNA topoisomerase 4 subunit A OS=Facklamia languida CCUG 37842 GN=parC PE=3 SV=1
KTMTIPEERVYVSITKEGYIKRTSVRSFTASD--S---------LD-YPLFV-RESTHDAVVILTSRGNYLHLPVYELPD-----LGLHWSQRYQL-EGE
Q--AVFSQKDS-NEDRLVMMTQSGRIKQTALSEFT----RTMTAIKMQ-ADRLVA---R--TYQVALMTYRSYGL------V--QGLKAQGVIAMKLK--
-DVVAGFLIDQRPQVLILTQRANLKRMDLE------RGALGTLIL----KLPHRQ-EAVALV--VPVIIQGDTGQTWELMA-DIGL---LNNGSALQAEV
L--VVGLHIAR-
>tr|E4KQ18|E4KQ18_9LACT DNA topoisomerase 4 subunit A OS=Eremococcus coleocola ACS-139-V-Col8 GN=parC PE=3 SV=1
QSLLVNEEQVMVTVTKEGYIKRTSLRSFATSD--T---------LD-YVIFA-QESTYQALVLITNKGQYIHLPVHELPD-----LGMHLSQQYNL-TGE
Q--FVSPASDQYKDQYLVMATKEGMIKKTPLTDFV----RPSQAMKMK-TDEIIG---K--VAQVILLTEKSYSL------V--YGLKAQGVTAINLK--
-DLAAFLLDNQQAQIILMTQRGNIKRFDNQ------RGSRGILML----KLPHRL-SAALIQ--QMLEVTGDTGFVVTIQA-QVPK---LANGSSLDQLD
L--VLVLRQSP-
>tr|K1MKB1|K1MKB1_9LACT DNA topoisomerase 4 subunit A OS=Facklamia hominis CCUG 36813 GN=parC PE=3 SV=1
RTLLIPQEQVYVSVTREGYMKRTSLRSFGASD--T---------QD-YPIFV-RESTHDAIVVLTSCGNYLHIPVNELPD-----LGIHWSQNYQL-EGE
E--AVFAQTSA-DRSNLVLVTAKGRAKQTPLSEFT----RSAQAIKLQ-SDRLVA---H--RYDLVLLTRRSYGL------I--QGLKAQGVMAIKLK--
-DVAAAFVIHQRPQVFLLTQRGNVKRIDVA------RASVGNLIL----KLPHRI-GAVALI--VPLIIQGDTGQQVELQA-DIPL---YNNGSTLADLD
L--VTNLHIAR-
>tr|A0A0G0YEE2|A0A0G0YEE2_9BACT DNA gyrase subunit A OS=Parcubacteria (Uhrbacteria) bacterium GW2011_GWF2_41_16 GN=gyrA PE=3 SV=1
MEDVIPDLPAIVMITQGGYIKRLSPDTFRQQERGG-G--LLT--ED-EVEQLFSTTTHRDLLFFTSRGRVFQMKAYDIPES-RTAKGTALVNFL-NAG-E
S--ATLSMA---GFKHLLMVTNKGTIKKTPFTDFEN-R-SGLIAIKLK--DNLEW---TD---DVMLVTSDGQSI------VRPMGRVASGVRGIRLKG-
-NVVGMDIISLPPQLLVVTEHGFGKRTPV-EYK-QARGGSGIKTA---QGKIGKV-AGRMVN-TRDLMVISMAGQVIRTAL-SISV-GR---GVRIMRFK
S-KVTSVAIV--
>tr|A0A0G1YPJ5|A0A0G1YPJ5_9BACT DNA topoisomerase (ATP-hydrolyzing) OS=Parcubacteria bacterium GW2011_GWA2_56_7 GN=UY95_C0005G0007 PE=4 SV=1
MEDVIPDAPTVVMITKGGYIKRLSPDTFKTQARGG-G--TQA--ED-TIDQVFTTSTHRDLLFFTNRGRVFKLKAYDVPEA-RTAKGQALVNFL-QAG-E
T--ATLSLG--ERYKYLIMVTSRGTTKKLDITEFES-R-SGLIAIKLH--DSLEW---T---DQVVLVTSGGQAI------VRAMGRVASGVRGIRLK--
ADVVGMSIVSGQWQLFVLMKNGFGKRTPI-EYK-QGRGGSGIKTA---TKKTGPV-ATRLVR-ARDVLVVSDAGQVVRTVL-SVSV-GR---GVRVMRFK
E-DGVATVALV-
>tr|A0A0G0J600|A0A0G0J600_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWC1_38_17 GN=gyrA PE=3 SV=1
EEDLVQAEEVIILLTKEGYIKRVSPDAWRTQLRGG-G--TMS--ED-VVDISLTSNTHDGLLFFTNKGKVYQSKAYEIPES-RTSKGRAIVNFL-NGE-E
K--AILSLK--EAEKYIILSTKNGIIKKTAIEDFDN-R-SGIAAIGLK--DSLSW---TD---EMILVTKNGIAI------VRPMGRVASGVTGIRLKK-
-GVVGMDVIQSSSKLLVVMENGYGKQTDI-EYK-QKRGGSGIKTA---TAKTGAI-DARIMS-EKDLIAISEKGQVIRTPI-SVSV-GR---GVRVMKLD
A-KVASVACI--
>tr|A0A0G0W9Z6|A0A0G0W9Z6_9BACT DNA gyrase subunit A OS=Microgenomates (Roizmanbacteria) bacterium GW2011_GWB1_40_7 GN=gyrA PE=3 SV=1
EEDLIQNEQTLITVSKTGYIKRLPRGTFKLQRRGG-G--MMT--ED-NIEHMITAQTHDYLMFFTNKGRVFRMRAWEIPES-RISKGQAVINLL-NQG-E
L--SILSTS--HPKSTILMATKNGVVKRTEFSQYQN-K-SGLITINLD--DEVVW---TR---DIMLVTHLGKTI------VRPTGRATRGVTGIKLSK-
-EVVAMEALKTFKDLLVITQNGLGKRTDV-EFR-QHRGGKGVKVA---TKKTGPA-IALLVN-SEQIVISSRKGIVIKLPI-NIPR-SR---GVILMRMK
G-PAAASAV---
>tr|A0A0G1FNV9|A0A0G1FNV9_9BACT DNA gyrase subunit A OS=Microgenomates (Gottesmanbacteria) bacterium GW2011_GWA2_43_14 GN=gyrA PE=3 SV=1
DEQLIANEETVIVITKTGYVKRQSPLSFKVQARGG-G--IMT--ED-SIEHLLSAFTHDNILFFTNKGKVYQLRVWDLPES-RVAKGQAIVNLI-NDS-E
I--SVLSYA--KKFAYITMATKKGTVKKTKLKEYEN-R-NGLVAVKLG--DELRW---SD---NILLVTHDGKSI------IRPTARDTMGVRGILTQS-
-GVVSMEIIDKQNDFLAIMEKGIGKKTPF-GFP-QHRGGQGVKVA---TKKTGKA-SAQMIP-CQNLVLTSNKGQVVKLPI-SVPR-SR---GVILMRFS
P-SVAAATCLS-
>tr|I7LE77|I7LE77_9LACO DNA topoisomerase 4 subunit A OS=Lactobacillus pasteurii DSM 23907 = CRBIP 24.76 GN=parC PE=3 SV=1
EKALVADEQVRVLISRDGYLKRSSLRSFQSTS--D---------SD-VIVYE-KTSTLANLYLFTNKGNVIYRPVHELTE-----TGQHLSQEL-G-SSE
Q--RVFEID---EQTNFLLATNDGYIKQLNLNNLQ----RAISAMKMK-SSVVVR---K--KQEIVLFTHKAYAV------I--SGAKAVGVKSVNLK--
-DIVNYVLLDPNTRVGIITDRGAFKQLEAN------RAKRGVLVL----RLPHRA-ALVAYG-NHVLKLVTSSLRKFDINT-DYPI---YSNGSFIIDPT
D--PNKLLLGR-
>tr|A0A0R1YJI8|A0A0R1YJI8_9LACO DNA topoisomerase (ATP-hydrolyzing) ParC OS=Lactobacillus hamsteri DSM 5661 = JCM 6256 GN=FC39_GL001015 PE=4 SV=1
EKALVADEQVRVLVSRDGYLKRSSLRSYQSTE--S---------GD-KVIYE-KTSTLANLYIFTNKGNVIYRPVHELTE-----TGQHLSQEI-G-QDE
Q--RVFAFD---QDVDFILATNDGYIKRLKLENLQ----RAITAMKMK-DSRLLQ---S--KKEITLFTNRAYAI------I--SGAKAVGVKSANLK--
-DVVGYVLVDPLIKVGIITQRGAFKQFELK------RAKRGVLVL----RLPHRA-AFTSYG-NHILHMTTSSDRHMDLKT-EFPL---YSNGSFVIDPT
D--PKSLELGR-
>tr|N2A8H8|N2A8H8_9LACO DNA topoisomerase 4 subunit A OS=Lactobacillus sp. ASF360 GN=parC PE=3 SV=1
EKALVADEQVRVLISRDGYLKRSSLRSYQSTA--E---------GD-AVIYE-KNSTLENLYLFTNKGNVIYRPVHELVE-----TGQHLSQEI-G-DDE
K--RVFNFK---QDLDFLLATNDGYIKRLKLANLQ----RAITAIKMK-DSHLLQ---S--NKEITLVTNMAYAV------I--SGAKAVGVKSVNLK--
-DVVGYVLVAPLIRIGLITQRGAFKQLELN------RAKRGVQIL----RLPHRA-ALTSYG-NHTLLLTTSSDRHVKIKT-EFPL---YSNGSFILDPS
D--PISLELGR-
>tr|E3J256|E3J256_FRASU DNA gyrase subunit A OS=Frankia sp. (strain EuI1c) GN=gyrA PE=3 SV=1
IEDLIAQEDVVVTVTRGGYAKRTKTDLYRSQKRGGKGVQGA-AREDDIVEHFFVTTTHHYLLFFTNKGRVYRAKAHELPEQARSAKGQHVANILAFGQDE
RIAEVMAIR---AP-YLVLATKRGLCKKSALTDFDS-RAGGLVAINLRE-DEVIGAR--GADDDLLLVSRNAQSIRFHE--LRPMGRATAGVIGMRFD-D
-DLLSIEVIKPTASLLVATSGGFAKRTHLNEYPLQGRGGKGVLTARIV-PSRGNLVGALVVED-DQLYAIASNGGVLRTVARDVRQ-QRQTMGVKLIDLE
-GQVVGVARNA-
>tr|A0A0F7X1F5|A0A0F7X1F5_CHLPN DNA gyrase subunit A OS=Chlamydia pneumoniae GN=gyrA PE=3 SV=1
IEDIITNESVIITISGDDYVKRMPVKVFKEQRRGGHGVTGFDM-GAGFLKAVYSAFTKDYLLIFTNFGQCYWLKVWQLPEGERRAKGKPIINFLEGRPGE
ELAAILNIK-F--G-FLFLATKRGVVKKVSLDAFSNPRKKGIRALEIDEGDELIAACIVSDEEKVMLFTHLGMAVRFPH--VRPMGRTARGVRGVSLKE-
-KVVSCQIVTENQSVLIVCDQGFGKRSLVEDFRETNRGGVGVRSI--NE-RNGNVLGAIPVTDHDSILLMSSQGQAIRINMQDVRVMGRSTQGVRLVHLK
-GALVSMEKLS-
>tr|A0A0B0EJ96|A0A0B0EJ96_9BACT DNA gyrase subunit A OS=Candidatus Scalindua brodae GN=gyrA PE=3 SV=1
MEDLISEEDVTVIITHEGYIKRLPLTTYRKQHRGGKGVTGAGM-EGDFVEDLFIASTHDYILFFTDMGKVYWQKVYDIPNASRIARGRAIVNLL-EGKDE
NVTSTIPVR---DRQ-LVMATKNGIIKKTVLSAFGRPKKGGIISILLDSGDKLIGVK-TQGGQEIVLGTENGKAIRFSE--VRCMGRATRGVKGIELK--
-DVKGIVVVDK-ATLLTVCENGFGKRTDYSEYSVQHRGGQGVINI--SR--NGKVVALMNVSDENELMMMTAKGMIIRAATNTIRSIGRNTQGVTLISLK
-GKVVSVAPVI-
>tr|A0A068NXL1|A0A068NXL1_9BACT DNA gyrase subunit A OS=Fimbriimonas ginsengisoli Gsoil 348 GN=gyrA PE=3 SV=1
PEDLIPEEEAIISISRDGYIKRVSVDAYRQQKRGG-G--NTM--ED-EPAHLFQVNTHHTILFFTDRGRVYRLKAYEIPEG-RYARGMPVINYI-NVG-E
R--ATISVK--NIDGYLTMITRHAEIKRTSLRDFAN-R-NGLIAFDIE--DELGW---TD---DVILITREGQSI------ATSRSRAAGGVRAISFKE-
NRVVSAAM---NMTLLVVGEHGYGKRTPL-DYR-QGRGGSGILTM---TEKTGKI-GAEVVE--DRLLVMTNKGKGIRMKV-EIRT-AR---GVKLVNLA
G-SVSSIARIV-
>tr|L8XWA2|L8XWA2_9SPIR DNA gyrase subunit A OS=Brachyspira hampsonii 30599 GN=gyrA PE=3 SV=1
EEDLIHDEDVAVSITTQGFIKRVPASSYRTQGRGGVGVQGGKS-GEHYIEHLFVASTKDYLFIFTDRGKAFWMKVHEIPALSKISQGKSIKFILNLAPEE
KITSYFTVS---PKQSIIMVTKMGTIKKMELKHLENAKKRGILALTLENNDELVAVSPVQTGDDFIMTTASGLALRITE--IRKMGRAAAGVKGIALD--
-VCVSGNAI--GESLIVITENGIGKRLSSKQFNVKGRGGKGQIYI--DN-KTGNVVSVKTVGDKDEIMVVTTDDMTIKIKADSIPELGRNAKGVKIVNIS
-GRVSDLAVVP-
>tr|G7H7A9|G7H7A9_9ACTN DNA gyrase subunit A OS=Gordonia araii NBRC 100433 GN=gyrA PE=3 SV=1
DEDLIAREDVVVTITETGYAKRTKTDLYRSQRRGGKGVQGA-GKQDDIVAHFFVSSTHDWILFFTTKGRVYRAKAYELPEAARTARGQHVANLLAFQPEE
RIAQVIQIK---AP-YLVLATRNGLVKKSKLEDFDS-RSGGIAAINLRG-DELVAAR--SAEDDLLLVSAHGQSIRFSE--LRPMGRQTSGVQGMRFN-G
-DLLSMVVVDEDDYLLCATSGGYAKRTRMAEYPVQGRGGKGVLTIQHD-KKRGELIGALRVND-SELYAITSSGGVIRTLSKQVRR-GRQTKGVRLMNLD
-GTLLAIARNA-
>tr|M0QDV8|M0QDV8_9ACTN DNA gyrase subunit A OS=Gordonia soli NBRC 108243 GN=gyrA PE=3 SV=1
DEDLIAREDVVVTITETGYAKRTKTDLYRSQRRGGKGVQGA-GKQDDIVRHFFVCSTHDWILFFTTKGRVYRAKAYELPEANRTARGQHVANLLAFQPEE
RIAQVIQLK---QP-YLVLATLNGLVKKSKLEDFDS-RSGGIAAINLRG-DELVGAQ--SADDDLLLVSKKGQSIRFSD--LRPMGRQTSGVQGMRFN-D
-DLLSLSVVRDDTFLLVATSGGYAKRTPIEEYSAQGRGGKGVLTIQYD-PKRGDLVGAIIVDE-SEVYAITSGGGVIRTLAKQVRK-GRQTKGVRLMNLD
-GTLLAIARNA-
>tr|Q6F2B2|Q6F2B2_MESFL DNA gyrase subunit A OS=Mesoplasma florum (strain ATCC 33453 / NBRC 100688 / NCTC 11704 / L1) GN=gyrA PE=3 SV=1
DEELIPDVKTMILLSDEGYIRRVDPEEFRVQKRGG-G--SVN--ED-PIVIATMGKMRDWVLFFTNSGKVFRTKAYNIRQS-RTARGLPIVNFL-NLG-D
K--AILPLRK---MNYLTFITEKGMIKKTDISLFDN-N-NGKIAINLK--DQLVT---T---DTIFVANKSGKVI------VRPLSRTASGVKAIKLD--
NDVVGAVTS--IENITTISSKGSFKKTNI-EYR-SGRNGKGIKVM---NEKTGDK-SIIAAR-TDLVCIISTDGNLIKTKA-DIPV-GR---GVRGIRLS
G-KIQAVMLEY-
>tr|A0A0L1IHS2|A0A0L1IHS2_9MOLU DNA gyrase subunit A OS=Mycoplasma sp. HU2014 GN=gyrA PE=3 SV=1
DEELIPDTKTMILLSKEGYIRRVDPDEFRTQKRGG-G--SN---SD-PIDLITMGKMRDWVMFFTNSGKVFRTKMYNIRQS-RTARGLPIVNFLND-E-D
K--AILCFR--K-FEYLTFVTQNGMIKRTRVSEFEN-N-NGKKAITLK--DQLVS---TD---TIFVANESGKVI------IRAMSRTGSGVKSIKLE--
-NVVGAVSSF-LSHITTVSSKGIFKKSLV-DYR-SNRNTKGMKVM---NEKTGKK-ALIAAR-TDLIVIVSSDGNIIKTKV-NIPS-SR---GVKGIRLD
G-EISAITLEY-
>tr|M9WAV2|M9WAV2_9MOLU DNA gyrase subunit A OS=Mycoplasma putrefaciens Mput9231 GN=gyrA PE=3 SV=1
DEELIPDVKTMILLSEEGYIRRIDPDEFRTQKRGG-G--SVN--ND-PIDIITMGKARDWVLFFTNSGKVFRTKMYNIRQS-RTSRGLPIVNFL-NLE-D
K--AILCLRK---FNYLTFVTQNGMIKRTKIAEFDN-N-NGKKAITLK--DQLVS---T---DSVFVANQSGKVI------IRSMSRTGAGVKSIKLE--
NDVVGAVSS--LTHITTVSSKGIFKKTSV-DYR-SNRNTKGIKVM---NDKTGKK-ALIPAR-SDLIVIVSSDGNIIKTKV-SIPT-SR---GVKAIRLD
G-EIKAITLEY-
>tr|A0A0C2VFR6|A0A0C2VFR6_MYCCA DNA gyrase subunit A OS=Mycoplasma capricolum subsp. capricolum GN=gyrA PE=3 SV=1
DEELIPDLKWMILLSQEGYIRRINPDEFRIQKRGG-G--SVN--ND-PIDIATMGKAKDWVLFFTNSGKVYRTKLYNIRSS-RTARGLPIVNFL-NLE-D
K--AILPLRK---FNYLTFVTQKGMIKRTKISEFEN-N-NGKKAINLR--DQLVS---T---DTIFIANESGKVI------VNPQSRVGSGVRALKLE--
NDVVGAISS--LTHITTVSNKGLFKKTPI-DYR-SGRNGKGIKVM---NQRTGKK-AIIDAR-TDLILIISSDGNLIKTKV-NIPS-SR---GVKAIRLA
N-EINAITLEY-
>tr|E3GHQ6|E3GHQ6_EUBLK DNA gyrase subunit A OS=Eubacterium limosum (strain KIST612) GN=gyrA PE=3 SV=1
VEDLIEEEEVVITMTHIGYVKRISADTYRSQKRGGKGITALST-ENDFVEHLFTTTTHHFLLFFSNKGKVYRLKAFEVPEG-RTARGTAIVNILQLDP-E
KITTMIPVK---ADKCLIMATKQGIIKKTDLTEYDS-RKNGIIGINLREGDELINVR-VEE-EDIVMGTQKGYAIRFTS--VRPLKRTSIGVRGIELR--
-DVVGMDIVSD-LFVLCVSDNGYGKLTSGDQYRSQKRGGKGVQTYKVT-K-TGELVGFCVISD-GEIMMINNQGVVIKLEGNDISTVGRNTQGVRLMKLQ
GE-IATISKVY-
>tr|E6MIN2|E6MIN2_9FIRM DNA gyrase subunit A OS=Pseudoramibacter alactolyticus ATCC 23263 GN=gyrA PE=3 SV=1
VEDLIKEEEVVVTMTHVGYVKRIAADTYRAQNRGGKGISALST-ENDFIEHIFTTSTHDDLLFFTNKGKYYRLKAYEIPVG-RTSRGTAIVNILQLDPDE
SITTMIQVK---ADKYFVMATRHGLIKKTAMTDYES-RKNGINGINLRDGDELIKVQ-SDD-EDVVMGTHLGYAIRFKV--VNATGRMSMGVRGIGLR--
-DVVGMDLLI--NNVLCVAEKGYGKRTSADQYRVQKRGGKGIQTYKCT-K-TGNLVGFSVLEG-GEIMMINNDGIVIKLKGDDISQIGRSTQGVRLMKLK
GDRIATICKVQ-
>tr|H6LEA6|H6LEA6_ACEWD DNA gyrase subunit A OS=Acetobacterium woodii (strain ATCC 29683 / DSM 1030 / JCM 2381 / KCTC 1655) GN=gyrA PE=3 SV=1
IEDLIEEEEVVITMTHIGYVKRITADNYRSQKRGGKGITALST-ENDFVEHLFTTTTHHYLMFFTNLGKVYRLKAFEIPEG-RTARGTAIVNLLPLED-E
QIATMIPVK---ADKYLIMATKQGIIKKTDLTEYDT-RKNGIIAINLREDDELINVR-VEQ-EEIVMGTQCGYAIRFNS--VRPISRTSIGVRGIDLR--
-DVVGMDIVKE-LFVLCVSENGYGKLSASDLYRPQKRGGKGVQTYKVT-K-TGELVGFCVISD-GEIMMINNQGVVIKLEGNDITAVGRNTQGVRLMKLK
DE-IATISKVY-
>tr|F5WQN6|F5WQN6_ERYRF DNA gyrase subunit A OS=Erysipelothrix rhusiopathiae (strain Fujisawa) GN=gyrA PE=3 SV=1
DEDLIPVEDIVVTMTMNGYIKRTTVDSFNTQNRGGKGVRGIST-DEDTVDQFIAMSTHDYLLLFTNLGKVYRIRGFNVPSS-RTSKGIPVVNLLNLTE-E
TVKTLVKVA--DESKYAFFVTKQGIVKRVEVQEFES-RQNGKIAITLREDDELVGVR-TNG-NEIIIGGSNGKAVRFDE--VRSMGRTASGVIGFNVD--
-GVVGIATDRE-QYILAVTEKGYGKRTDIAEYRRTKRGAKGVKTVNIT-E-NGNLVSLRAV-G-EEALIISNEGTVIRTEISNIGIYGRSTIGVRLINVG
TD-VSQVAILQ-
>tr|F8I312|F8I312_SULAT DNA gyrase subunit A OS=Sulfobacillus acidophilus (strain TPY) GN=gyrA PE=3 SV=1
DEDLIPEEDMVVTITHRGYIKRLATSVYRPQRRGGRGIAGSTV-EDDFINHLFVASTHSYLCFFTNRGRIYRVKVHEIPEASRQAKGISVANLIALEQ-E
RIAAVQTLT----DHYWVFATKRGVVKRTPLSDYET-RGGGIIAITLDDGDELIGVE-TAG-SHIILATRHGQVIRFEE--VRPTGRAARGVTGIRLR--
DMVVSLATVSE-PELLILTENGFGKRTRLDQFRVTGRGGQGIVGMRVT-D-TGYVVGIQPVES-EECMVISSEGTMIRLEVGSISEQGRATQGVKVMRLE
G-HVSAFALVK-
>tr|F9MNN4|F9MNN4_9FIRM DNA gyrase subunit A OS=Megasphaera sp. UPII 135-E GN=gyrA PE=3 SV=1
VEDMIPDERMVLTLTRRGYVKRMNANVYHTQNKGGRGVRGMGT-EEDTVNHLLYTSSLHTVLFFTNLGRVYRLKAYEIPENNRNSKGIAAINILPLDEGE
KVNALIDLD---LSMHLFMATEQGLVKKTPLIEFKN-RRNGLIAISLVEGDHLAKVR-TKG-QRIILATKQGMAICFNE--VRPTGRNTRGVRGISLA--
-DVIGADVLA--CQVLTVSEEGFGKRNNMDAYNIQRRGGKGVKNFKIT-Q-TGAIVGVEVVRE-QELMLITTNGIVIRTDIESIGVKGRNTSGVKIQKLE
ENKVAALDTIT-
>tr|D3LST5|D3LST5_9FIRM DNA gyrase subunit A OS=Megasphaera genomosp. type_1 str. 28L GN=gyrA PE=3 SV=1
VEDMIPDERMVLTLTRRGYMKRINANVYHTQNKGGRGIKGMGT-DEDAVNHLLYTSALHTVLFFTNFGRVYRLKAYEIPENSRNSKGIAAINILPLSTGE
KVNALIDLD---PSMNLFMATENGLVKKTELAEFKN-RRNGLIAISLIEGDHLAKVR-TNG-QRIILATKLGMAICFNE--VRPMGRNTRGVRGISLA--
-GVIGADVLA--CQVLTVSEEGFGKRNNMDAYKIQLRGGKGAKNFKIT-P-TGVIVGVEVVRD-QELMLITTNGIVIRTDIESIGIKGRNTSGVKIQKLE
GDKVAALDTIT-
>tr|E2Z9D9|E2Z9D9_9FIRM DNA gyrase subunit A OS=Megasphaera micronuciformis F0359 GN=gyrA PE=3 SV=1
VEDLIPNERMVLTLTRRGYIKRINANVYHTQNKGGRGIKGMAT-DEDAVNHLLYTSAHNTVLFFTNFGRVYRLKSYEIPENSRNSKGIAAINLLPLSQGE
KVNALIDVD---PQANLFMATERGLVKKTSLQEFSN-RRNGLIAISLMDGDHLAKVR-TKG-QNIILATKQGMAICFKE--VRPMGRNTRGVRGITLA--
-DVIGADILA--SQVLTVSEEGFGKRNNVDAYKVQRRGGKGVKNFKIT-P-TGVIVGVEVVRT-QELILITSNGIVIRTDIESIGVKGRNTSGVKIQRLE
ENKVAALDTIS-
>tr|H1D1C1|H1D1C1_9FIRM DNA gyrase subunit A OS=Dialister succinatiphilus YIT 11850 GN=gyrA PE=3 SV=1
ITDLVPDEPMTITLTKQNYIKRMDSADIRVQRKGGRGVSGMKM-DEDYVWKILNTSTHNRILFFTNYGKVYMKTAIDLPKG-RTARGSALINYIPSSKGE
RVTELLDID-A-DTKYLLMVTKKGYVKKTEIAEYRNINKNGLIAIRLNEGDELVTVLRVKGDEDVILGTRFGMAIRFSI--VRSLGRAAAGVHGIRLSVG
-EVVGAVIAA-DKDIFTISADGNAKRNKADAYR-QGRNGMGVRNFKKG----FEVVALVAAD-NDELVGVSEQGITIKTKASQITSKAKAGQGVILQRLE
-GRIASIDVLS-
>tr|A0A062VBT7|A0A062VBT7_9EURY DNA gyrase subunit A OS=Candidatus Methanoperedens nitroreducens GN=gyrA PE=3 SV=1
IEDLIPKEDDVITVTNSGYIKRIPVDAYKQQRRGGKGVIGMET-DEDFVSDLFIANTHDYILFFTDRGKVYWLKVYEVPTAGRQARGTAIINLLQIEQ-E
KINAYIPIS----EHYLLMVTKKGVVKKTVLSVFSN-RKTGIIAISLDDGDKLVSVK-TDG-RGIVIGTKHGKAIRFNE--VRDMGRSAYGVRGVKLV--
DEVVSMAVVEE-ATLLTITEHGFGKRTGFEEYRIMNRGGQGVITIDVN-I-NGSVVDIKTVRD-DEIMVTTSRGIIIRVPVSGIRIQGRNTQGVKIMNVD
K-RVVGVATLA-
>tr|G7WPS6|G7WPS6_METH6 DNA gyrase subunit A OS=Methanosaeta harundinacea (strain 6Ac) GN=gyrA PE=3 SV=1
LEDLIQEEEVAVTITSDGYIKRQPLSAYRQQRRGGMGVMGADT-SEDFVTDLFIATTHEYILFFTDMGKAHWLRVFDVPSFGRTARGKSIVNLLSLEA-E
KITEAIPVK----EGFIVMATSLGQVVKTPIRAYSN-RKGGIKAVNLR-GDRLVAAR-TGG-QDLILATAGGKAIRFSE--VRPSNRGSMGVRGITLE--
DEVISMDVVRPGASLLTVTRQGYGKRTELSEYSPHRRGGKGMKNID---S-KGDVVASRTVSE-DELMITTKDGVMIRIPASDIRIQGRATQGVRIMRLK
-GEVAAVARIN-
>tr|F4BZL4|F4BZL4_METCG DNA gyrase subunit A OS=Methanosaeta concilii (strain ATCC 5969 / DSM 3671 / JCM 10134 / NBRC 103675 / OCM 69 / GP-6) GN=gyrA P
NEDLIQEEEVAVTITSSGYIKRQPVNTYRMQRRGGRGVIGAET-TEEFVTDVSTASTKDYLLFFTDKGKAHWLKVYEVPALGRAARGKSIVNLLQLEP-E
RIAGAIPVK-----GYIVLVTRSGNIVKMPLQAFSN-RKGGIKAVNLK-GDSLVSAK-TNG-KELLVATKFGKAIRFKE--VRASNRGTMGVKAISLN--
DELISMDVIEPGSTLLTVTNQGYGKRTELEEYPQQRRGGKGVKNID---A-KGYVCCTTTVSE-DELLVTTRDGVIIRIPASDIRVQGRSTQGVRIMNVK
-GEVAAIARIN-
>tr|D1YWG1|D1YWG1_METPS DNA gyrase subunit A OS=Methanocella paludicola (strain DSM 17711 / JCM 13418 / NBRC 101707 / SANAE) GN=gyrA PE=3 SV=1
DEDLIPVENVVVTISNTGYIKRQPVDTYRTQRRGGMGIMGMET-EEDFVVDVFTASTHDHLLFFTNKGRVYVLKVYEIPEASRQSRGKAIVNLLTLMP-E
SVNAMIPIK----KHYLIMCTREGTIKKTALSSFQN-RRTGIIAIGLDEGDELISVK-TNG-QEVLIATRNGKANRFSE--VRPMGRQAGGVIGIRLT--
DKVIGMEVVSE-ASILTVCENGFGKRTAISEYTPHHRGGQGMINIKTT-L-NGGVVAIASVTD-DQLLVVTRDGIMMRINVKDISEISRNTQGVKIITLK
ENAVVGVAKLV-
>tr|H8IA13|H8IA13_METCZ DNA gyrase subunit A OS=Methanocella conradii (strain DSM 24694 / JCM 17849 / CGMCC 1.5162 / HZ254) GN=gyrA PE=3 SV=1
DEDLIPRETVVVTISNTGYIKRQPLDTYRTQRRGGMGVMGMET-DEDFVVDVFAASTHDNLLFFTNKGRVYSLKVYEIPVASRQSRGKAIVNLLTLLP-E
SITAMIPIK----GHYLMMCTREGIVKKTPLSAFKN-RSTGIMAIKLDEGDELISVK-TNG-QEVLIATRDGKANRFHE--VRSMGRQAAGVIGIRLA--
DRVVGMEVLSE-ASILTVCENGFGKRTPVSEYTPHHRGGQGMINIKTT-L-NGGVVAVASVTD-DQILLVTRDGIMMRIKVKDVSEIGRNTQGVKIITLK
EDAVVAVAKLA-
>tr|I4ENK4|I4ENK4_9CHLR DNA gyrase subunit A OS=Nitrolancea hollandica Lb GN=gyrA PE=3 SV=1
DEDLIPEVNVLVMLTNRGYVKRLPDGTYRTQHRGGRGVTGMTV-ETDGVQRMVAANSHDSLLFFTNRGRVFHIKVHELPD-GRTAKGTPVINLIGIQPGE
AITTLLPVR-FD-ATYLFMCTRSGRVKRTRLDQFSSVRASGLIAISLDEGDELAWVRMTSGSDDLILVTEHGQSIRFH---VRAMGRQAAGVIGIRMN--
-RVIAAEVVA-DCDLLVVSANGYGKRTPLDEYRVQNRGGLGITAMKVTE-RNGPLAAARVVC-TDTIMLVSTHGMVIRVPAAQISR-GRATQGVGIMRVH
NDVVASLTVIR-
>tr|D1CB18|D1CB18_THET1 DNA gyrase subunit A OS=Thermobaculum terrenum (strain ATCC BAA-798 / YNP1) GN=gyrA PE=3 SV=1
DEDLIPNIEVAVSVTDRGYIKRLPPDTYRTQRRGGRGVNGVGV-DSDVVEHLLVCNTMDSVLFFTNKGKVYQIKAHEIPD-SRTSKGLPLVNLINLEPHE
RVTEVIAVR-FP-DRYLTTITKNGKIKRTSLEEYSSVRSNGLIAMSLEEGDELRDVRLLGDNDDILVLTAKGQSIRFP---VRPTGRQAIGVTAIRLS--
-EVVAMEVVQ-GAEILLVTKKGFGKRTSIDEFNRQARAGSGARAIKIDE-KTGDLATARMAP-DSEVLIASASGQVVRLKTNTISK-SKAARGVSLMTLK
PNSVTSLAIIA-
>tr|A0A0M2PSL4|A0A0M2PSL4_PROHO DNA topoisomerase (ATP-hydrolyzing) OS=Prochlorothrix hollandica PCC 9006 GN=PROH_20885 PE=4 SV=1
AGTAIEAERCVLEFSQRGYVRRHSRRKFQRHISLD-M----VK-ED-CPQDRAVVDETQEVLLLTPLGKAFTVKAQDLPPS-RRNRGMPLITALPEEP--
---RYFVLP--T-DLSLIALTRQGRIKRLPLADFQQ-T-RGLSFIKLK--DTLAF---Q----QLVLATSKGRLL------LPFMGRTAQGHNALRLR--
-QLVGCVSGA-SDELLFVSAKGYVKRTPI-LIP-GNRGDLGTTAF--TKT---DL-AVQRLM-QAWVTVVTDQDRMARLDG-TVPV-GR---GDRLIQPQ
D-SIVQVSVMA-
>tr|I7MR11|I7MR11_STRCB DNA gyrase subunit A OS=Streptococcus canis FSL Z3-227 GN=gyrA PE=3 SV=1
DEDLIEEEDVLITLSNKGYIKRLAQDEFRAQKRGGRGVQGTGV-DDDFVRELVSTSTHDTLLFFTNFGRVYRLKAYEIPEYGRTAKGLPIVNLLKL-EGE
TIQTIINAR--A-GKSFFFTTKQGVVKRTEVSEFNN-RQNGLRALNLKEGDQLINVL-TDG-DDIIIGTQSGYSVRFNE--IRNMGRSATGVRGVKLR--
-EVVGASRIQDKQEVLVITENGYGKRTSATEYPTKGRGGKGIKTANIT-P-NGQLAGLVTVDT-EDIMVITNKGVIIRTSVANISQTGRATLGVKVMKLD
D-KIVTFALVE-
>tr|A0A0P6SNY2|A0A0P6SNY2_9STRE DNA gyrase subunit A OS=Streptococcus phocae GN=AKK44_00535 PE=4 SV=1
DEDLIEEEDVLITLSNKGYIKRLAQDEFRAQKRGGRGIQGTGV-DDDFVRELVSTSTHDTLLFFTNFGRVYRLKAYEIPEYGRTAKGLPIVNLLKL-DGE
TIQTIINAR--L-DKFFFFTTKQGVVKRTSVTEFHN-RQNGLRAITLKDGDELINVL-TDG-EDIIIGTRLAYSVRFKE--IRHMGRSAAGVRGVRLR--
-GVVGASRIQDNQEVLIITENGYGKRTSAVEYPTKGRGGKGIKTANIT-A-NGQLAGLMTVDT-EDIMVITDKGVIIRTNVTNISQTGRATLGVKVMRLD
D-SIVTFALVE-
>tr|R9M4X8|R9M4X8_9FIRM DNA gyrase subunit A OS=Oscillibacter sp. 1-3 GN=gyrA PE=3 SV=1
IEDLIEEEECVFTLTQAGYIKRTPVSEYTAQSKGGMGKKGITT-EEDVVEDVFTASTHDYILFFTDSGKVYRKKGYQIPE-GKTAKGTNIVNILQVEQGE
RVQTMIHTR-IDDGRFLFMVTRNGTVKRLPANTLKNLRNNGLRALRMDEGDRLITVRETDGEQKILIATHDGLAVCFD---VRPMGREAMGVRGIRLR--
-YVVGAARA--GHEVLSITERGYGKRTPVEEYRITNRGGVGIKNYMITD-KTGAVVGIKVVD-SEDLLLMTQTGILIRTHVESIRL-GRATQGVIVMRFK
EGRVISMALTE-
>tr|R5DBP1|R5DBP1_9FIRM DNA topoisomerase (ATP-hydrolyzing) OS=Firmicutes bacterium CAG:83 GN=BN795_01459 PE=4 SV=1
IEDLIEEEECVFTLTENGYIKRTAVSEYTAQSKGGMGKKGITT-DEDTVVDVFTASTHDYLLFFTDTGKVYRKKGYQIPEG-KTARGTNIVNILQVEQGE
RIQTMLHYRE--GQLYLFMTTRNGTVKRLPVETLKNLRNNGIRALTLDEGDELINVQETDGSQRILIATHDGQAVCFD---VRAMGRTAVGVRGIRLR--
-YVVGAARA--GKTVLSITERGYGKRTPVEEYRITSRGGLGIRNYMVTE-KTGPIVGIKVVD-QEDLLLMTQAGILIRTAVDSIRI-GRATQGVIVMRFK
EGRVISMALAD-
>tr|R6TJ75|R6TJ75_9FIRM DNA gyrase subunit A OS=Oscillibacter sp. CAG:155 GN=gyrA PE=3 SV=1
IEDLIEEEDCVFTLTQAGYIKRTPVSEYTAQSKGGMGKKGITT-DEDVVTDLFTASTHDYLFFFTDTGKVYRKKGYQIPQ-GKTAKGTNIVNILQVEQGE
KIQTMVHTR-LDENRFLVMVTRNGTVKRLPVSTLKNIRASGIRALRMEEGDQLISVRETDGTRKILVATHDGQAICFD---VRPMGRDAMGVRGIRLR--
-YVVGAARA--GKTVLSITEKGYGKRTPVEEYRITGRGGLGIRNYAVTE-KTGGVVGIKVVD-SEDLLLVTKGGILIRTPVENIRV-GRSTQGVIVMRFK
EGQVISMALTD-
>tr|R5AYI2|R5AYI2_9FIRM DNA gyrase subunit A OS=Firmicutes bacterium CAG:103 GN=gyrA PE=3 SV=1
IEDLIEEEQCVFTLSHGGNIKRVPVDEYTAQKRGGKGVRAATL-DEDYVDTVFTASTHDYILFFTNRGRCYRKKGYLIPE-GRTARGVNIVNFIQVEKDE
QVNAMLHVR-MD-DSFLVFATRSGTVKRMPLSALRNIRTSGIRALTLDEGDELINVMRTDGSRNILLATHNGQAICFA---VRPMGREAVGVRGIRLK--
-WVVGAEIA--DADVLSITENGYGKRTPAADYIRQHRGGSGMKNYNITD-KTGPVAAVKVVQ-SDDVLVVSDDGVIIRMEAAGISV-GRATQGVRIMRLS
EGRVISVALTD-
>tr|A0A0G3WJL7|A0A0G3WJL7_9BACT DNA gyrase subunit A OS=Endomicrobium proavitum GN=gyrA PE=3 SV=1
IEDLIKEEEVAVTMSHAGYIKRIPLDTYRAQGRGGRGITAMGT-DEDFVESLFITSSHAYMLFFTSRGRLYWMRAYEIPE-VRTSKGKAIVNLLQLSAEE
KITAAIAFR--K-GEYLLMCTRNGTIKKIALTEFSNPRKGGIIAIKLEDGDILTEVKAIAKNPEVLIATKKGQAVHFK---VRAIGRAGMGVKGVELE--
-EVIGMEVLS-KDVILTVSEKGYGKRTEVGKYRLTHRGGKGVINMDTTD-KVGVVIGIK-KA-DGELMIMTQNGITIRLKVNSISV-GRNTQGVRLVRLD
EGKVAAIASVV-
>tr|B1GZ07|B1GZ07_UNCTG DNA gyrase subunit A OS=Uncultured termite group 1 bacterium phylotype Rs-D17 GN=gyrA PE=3 SV=1
IEDLIQEEEVAVTMSHAGYIKRIPLDTYKAQHRGGRGIAAMNT-EEDFVENLFITSSHSYMLFFTTRGRLYWMRIYEIPEA-RTSKGKAIVNLLQLQGEE
KITAAIPIR-F--DEYLLMCTRNGIIKKIALDKFINPRKRGIIAIKLEDGDILTEVKAIN-NPEVVIATKKGSSIRFK---IRVIGRAGRGVKGIELK--
-EVIGMEVFSP-DVFLSISENGYGKRTKVGKYRLQKRAGHGVINMQMSE-RNGNMIGIKKAN-GEEVMIITQNGITIRLRVNSISV-GRNTQGVRLVRLD
-GKVAAIACVV-
>tr|V8AMJ6|V8AMJ6_9LACT DNA topoisomerase (ATP-hydrolyzing) OS=Lactococcus garvieae TRF1 GN=N568_0111185 PE=4 SV=1
DEDLIEEEDVLITLSNKGYIKRLSNDEFRAQKRGGRGVQGMNM-DDDFVQHLVSTSTHDHLLFFTNLGRVYRMKGYEIPEYGRAAKGLPIVNLLKL-DGE
KIQTVINVV---EERYLFFTTRKGLVKRTNTQQFAN-RTNGLKALNLREGDELINVL-TSG-ENIIIGTHNGFSVRFEE--VRDMGRSATGVKGVSLR--
-GVVGTAIVHDEQEVLVISEKGLGKRTIASEYPVKGRGGKGIKVMNIT-D-TGKLAGLTAIND-EDIMVITDTGVVIRTSVDNISQTGRAAQGVKIMRLD
D-QIVTFALVE-
>tr|Q9CGI5|Q9CGI5_LACLA DNA gyrase subunit A OS=Lactococcus lactis subsp. lactis (strain IL1403) GN=gyrA PE=3 SV=1
DEDLIEEEDVLITLSNKGYIKRLANDEFRAQNRGGRGVQGMGM-DDDFVQHLVSTSTHDHLLFFTNLGRVYRMKGYEIPEYGRTAKGLPIVNLLKL-DGE
KIATIINVD---AAKYLFFTTRNGIVKRTSTSQFSN-RTNGLKALKLRDGDELINVL-TSG-DEVIIGTHLGYSVRFKG--VRDMGRAAAGVKGVNLR--
-GVVGTSRIDDSQEVLVISENGLGKRTQASEYPTKGRGGKGMKVMNVT-E-TGKLAGLTAVND-EDLMVITDTGVIIRTNVANISQTGRAAQGVKVMRLD
E-QIVTFALVD-
>tr|A0A0Q0EGC4|A0A0Q0EGC4_CHLPS DNA gyrase subunit A OS=Chlamydia psittaci str. Frances GN=GWI_04705 PE=4 SV=1
IEDIITNEPVIITISGDDYVKRMPVKVFREQKRGGHGVSGFDM-GSDFLKAVYSASTKDYLLIFTNFGQCYWLKVWQLPEGERRAKGKPIINFLKGRPGE
QLAAVLNIK-F--G-FLFLATKHGVVKKVALDAFSNPRKKGIRALEIDDGDELIAAVITSEDEKVMLFTRLGMAVRFPH--VRPMGRTARGVRGVSLKE-
-RVVACQIVRDDQSVLVVCDNGFGKRSQVEDFRETNRGGVGVRSI--NE-RNGDVLGAISVTDYDSILLMSAQGQAIRINMQDVRVMGRSTQGVRLVHVK
-GTLVAMEKLS-
>tr|A0A0M4H4D9|A0A0M4H4D9_9ENTR DNA gyrase subunit A OS=Buchnera aphidicola (Aphis glycines) GN=gyrA PE=3 SV=1
IEDLINQEDVVVTLSHSGYVKYQPISDYNAQKRGGKGLAAK-TKEEDFIQSLVIANTHDTILCFSSRGILYWMKVYHLPESSRHAKGRPIVNLLPLT-KE
RITAILPVHEYKDNLNIFMATAQGVVKKSALKNFQKPRSAGIIAINLRANDELIGVALTNGKNNVMLFTQNGKVVQFSENSVRTMGRTASGVRGIKIL--
KSVVSLIIPSE-ESILIATNNGYGKRTKISDFPIKSRATQGVISIKITK-KKGKIIGAIQVVETDQIMMITDAGTLVRIRVSEIGVLKRNTQGVILIRTS
KNKVVALQRIV-
>tr|F7WZ57|F7WZ57_9ENTR DNA gyrase subunit A OS=Buchnera aphidicola (Cinara tujafilina) GN=gyrA PE=3 SV=1
LEDLITKETVVVTLSHSGYVKYQPISDYNAQKRGGKGSAAK-TKEKDYIENLLVANSHDTILCFSSRGILYWMKVYQLPEKSRHTRGRPIVNILPLT-RE
RITTILPITKYKSSINIFMATAHGFVKKTSLNKFQKTKKFWYYAINLRKNDKLIGVSLTNGHDTIMLFSSNGKIVHFSEKTIRNMGRMASGIKGMKIS--
EKVVSLLVPNK-DNILIVTEHGYGKQTKINQFPIKSRATKGIISIKTTK-KNGIVIGALQVKNDDQIMMITNAGKLVRTRISEIGILKRNTQGVILIRAS
KNKVVGLQKIK-
>tr|Q057V6|Q057V6_BUCCC DNA gyrase subunit A OS=Buchnera aphidicola subsp. Cinara cedri (strain Cc) GN=gyrA PE=3 SV=1
IEDMIVKETVVVTLSYSGYVKYQPISDYNAQKRGGRGSAAK-TKEEDYITNLLVANSHDTILCFSSRGLLYWMKVYQLPETSRNARGKPIVNLLPLT-KE
RITTILPISKYKSSINIFMATALGFVKKTSLIQFKKPRNSGIIAINLRKNDKLIGVSLTTGNNNICMFTSKGKVVQFSEKTIRKMGRTASGIRGMKIT--
NNLVSLLVPNK-DDILIVTANGYGKRTNINQFPIKSRATKGVLSIRVTQ-KNGVVIGAIQVKQNDQIMIITNAGTLVRTRVSEIAILKRNTQGVILIRTI
KKKVVGLQKLS-
>sp|P57277|GYRA_BUCAI DNA gyrase subunit A OS=Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) GN=gyrA PE=3 SV=1
MEDLINQEDVVVTLSHSGYVKYQPLSDYNAQRRGGKGSAAK-IKEEDFIESLVIANTHDTILCFSSRGILYWMKVYQLPESSRHARGRPIVNLLPLS-KE
RITAILPVHKYQDNLNIFMTTAHGIVKKSSLSQFKKPRFAGIIAINLHANDELIGVALTDGNNNIMLFTQNGKVVQFLENSVRTMGRTASGVKGIKIK--
KNVVSLIVPKN-GSILIATKNGYGKRTKISDFPIKSRATQGVISIKITK-KNGKIIGAIQVIEKDQIMMITDAGTLVRIRVSEVGVLKRNTQGVILIRTS
KNKVVALQKIV-
>tr|R6DNX2|R6DNX2_9FIRM DNA gyrase subunit A OS=Firmicutes bacterium CAG:238 GN=gyrA PE=3 SV=1
EEDLIEEENVCITLTHLGYIKRVPVDTYKSQRRGGKGVTGITT-ENDFVKNLIMTSTHDYLMFFTNTGKAHKIKAYEIPET-RTAKGTPAVNFLNLMQRE
RITAVIPIK---EDKFLIAVTKQGTIKKTALSNFDT-RKTGLIAMNLKDGDELIGIK-TSG-NNVIIVTKNGKCICFSE--VRPMGRIAGGVRAIKLE--
-DVVAMELVE--QELLVVTKKGFGKRTKVEDYKIQVRGGKGLLTYDKF-K-TGELVGAMAVDD-DEILLINSDGIIIRMAAKEISKLGRATQGVKIMNVG
EENIIALAKVI-
>tr|V1CK51|V1CK51_9FIRM DNA gyrase subunit A OS=Eubacterium brachy ATCC 33089 GN=gyrA PE=3 SV=1
EEDLIEKENVAVTLTHLGYLKRIPADTYKTQKRGGKGITGLTT-ENDFVTDLIMTSTHDYLMFFTNFGKVYKIKAYEIPET-RTAKGTPAVNFLNLLQRE
RINAVMPIE---EDAFLLGVTKKGTIKKTSISEFET-RKNGLIAINLRDGDELIDIK-TSG-DDIIIVTKHGKSIRFSE--VRATGRAAMGVRALKLG--
-GVISMCLVN--DKLLVVTQNGFGKRTPVKDYKKQERGGKGILTYDKF-S-TGELVGAVTVED-DEVLLINSDGIIIRIEAKDVSEFGRATQGVKIMKVE
EDNIISMTKVI-
>tr|C7H086|C7H086_9FIRM DNA gyrase subunit A OS=Eubacterium saphenum ATCC 49989 GN=gyrA PE=3 SV=1
EEDLIERKNVTITLTHKGYAKRMDVDEYKTQKRGGKGITGLKT-ENDFVKNIINTSTHDDLLFFTNYGKAHKIKAYQIPE-TRTAKGIPIINFVNLDKTE
EITAVIPID-FE-DKYLIAVTSQGLIKKVKLSEFESNRKSGLIAVKLHDGDKLIAIEKTNGDDDVLIVTRKGMSIRFN---VRATGRQSIGVKAITLK--
-EIISMQLVS-GKELLVVSKKGYGKRTGTDKYTLQTRGGKGNKTYDNFD-VTGELTGALIVD-EDDIMLINSDGIVIRIKAKEIPN-SRATKGVRIMKVG
DANIISLAKVM-
>tr|W2C1H0|W2C1H0_9FIRM DNA gyrase subunit A OS=Eubacterium nodatum ATCC 33099 GN=gyrA PE=3 SV=1
DEDLIEEENVAVTLTHLGYIKRVPADTYKAQRRGGKGIMGITT-DNDFVKDLIMTSTHDYLMFFTNTGKAHKLKAFEIPES-RTARGTPAVNFLSLMQRE
RITALIPVK---EDKYLIAVTKQGTIKKTSLSEYNT-RTSGIIAIKLKDDDRLIDVK-TTG-NSVIIVTKKGKCICFSE--VRAMGRIAGGVRAIKLD--
-DVVSMSLVD--QELLVVTENGYGKRTPVKEYKIQVRGGKGLLTYDKF-K-TGALIGAMVVDD-DEVLLINSEGIIIRIRANEISELGRATQGVKIMKVQ
DEKIVAMAKVI-
>tr|R6ER32|R6ER32_9FIRM DNA gyrase subunit A OS=Firmicutes bacterium CAG:145 GN=gyrA PE=3 SV=1
EEDLIEEEKVCITLTHLGYVKRVPVDTYRAQKRGGKGITGLTT-DNDFVKNMIMTSTHDYLMFFTNTGKAHRIKAYEIPET-RTAKGTPVVNFLNLLQRE
RVTAVIPIK---EDRFLVGVTKDGIIKKTALANFDT-RKTGLIAMNLKEGDQLIDIR-TSG-NNVIIVTKHGKCISFSE--VRPMGRIAGGVRAIKLE--
-DVVSMELVE--QELLVVTEKGYGKRTKVEEYKIQVRGGKGLLTYDKF-K-TGQLVGAMVVDD-DDVMLINSNGIIIRMQAKEISRLGRATQGVKIMNVA
DDNIIALAKVA-
>tr|H1PJD4|H1PJD4_9FIRM DNA gyrase subunit A OS=Eubacterium infirmum F0142 GN=gyrA PE=3 SV=1
EEDLVEEENVTITFTHLGYIKRVPADTYKAQKRGGKGITGVTT-DNDFVKDLVMTSTHDNLMFFTNTGKAHKIKAYEIPET-RTARGTPAINFLNLLQRE
RITAVIPVK---DDKYLIAITKNGLIKKTALNEFDT-RTTGLIAINLKDEDELIAIK-STG-NNIIIVTRKGKCICFSE--VRPMGRIASGVRAIKLD--
-DVVSMELVE--QQLMVVTENGFGKRTPVEEYKIQVRGGKGLLTYDKF-S-TGALIGAMVVDS-DEILMINSDGIIIRIRASEVSILGRATQGVKIMKVE
EGKIVAIAKAI-
>tr|J6HDK5|J6HDK5_9FIRM DNA gyrase subunit A OS=Mogibacterium sp. CM50 GN=gyrA PE=3 SV=1
EEYLIDEEDVAVTLTHLGYIKRVPENTYKAQRRGGKGIVGLTT-DTDFVKDLIITSTHDYLMFFTDLGKVYKIKAYEIPES-RTAKGTPVINFLNLDQGE
RVTAVIPVK---DDNYLIMVTKNGTIKKTPMSQFDT-RKTGLIAITLKDDDKLIAVS-SSG-ESVYVITKKGKSITFPE--VRSMGRSAGGVRAISLD--
-GVVSMELDS-ERELLVMTKKGFGKRTNLDEYRVQTRGGKGVATYDKF-A-TGELVGATLVSD-DEIMLINSNGVIIRIRANEISKSGRTTQGVKIMKVE
DGEIVSFAKVL-
>tr|A0A0G1LCP7|A0A0G1LCP7_9BACT DNA gyrase subunit A OS=Parcubacteria (Giovannonibacteria) bacterium GW2011_GWB1_44_23 GN=gyrA PE=3 SV=1
AEDLVPEEETILILTQGGYVKRIKPDEYRVQRRGG-G--IVT--ED-VAYEFISGNTHDDLLFFTNLGKVYQTKMYEIPET-RQSKGKAIANFL-SSD-E
K--SVLPVP--GQASYVILSTQKGVTKKVDSKDFED-R-SGIRAINLQ--DTLRF---M---EEVALSSKLGQAV------IRPMGRTAQGIRGMRLKN-
-DIVGMDILPQKLEILSVSQQGYGKKTNI-QYR-QKRGGSGVKTC---TSKTGPV-SVQVVK-QQEIIAISKKGQVIRAPL-QIPS-SR---GVRIMKVN
G-AVASVTLL--
>tr|A0A0G1L2U2|A0A0G1L2U2_9BACT DNA gyrase subunit A OS=Parcubacteria (Giovannonibacteria) bacterium GW2011_GWA2_44_26 GN=gyrA PE=3 SV=1
TEDLVPEEETILILTQGGYVKRIKPDEYRVQRRGG-G--IVV--ED-VAYEFISGNTHDDLLFFTNLGKVYQTKMYEIPET-RQAKGKAIANFL-SAD-E
N--SILPVP--GEKNYVMLSTERGLTKKVEAKGFED-R-SGIRAINLK--DTLRF---S---EEAILSTKLGQAV------IRAMGRTAQGVRGMRLKN-
-DIVGMDIITSKPEILSVSSLGYGKKTSV-QYR-QKRGGSGTKTS---TSKTGPV-SVQVVK-QVEIIAISKKGQVIRAPL-QIPS-SR---GVRIMKMN
G-SVASVTLL--
>tr|A0A0G1R0T7|A0A0G1R0T7_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWA2_47_10 GN=gyrA PE=3 SV=1
DEDLIPEEDTIIVLTQGGYIKRIKPDAYKVQKRGG-G--MIE--ED-AVMHFITANTHSDILFFTNGGKVYQIKAYEVPES-RVSKGKAIFNFL-SST-E
Q--SVLAAPKKGGTGFLVMVTKNGIIKKVDAHSFES-R-SGLIAIKLK--DTLRW---T---DELVLVTKLGKAI------VRPMGRNAAGVRAMRLGG-
-DVVGMDIVSEGSELIVVTENGFGKRTPL-EYK-QRRGGSGIKTA---TSKNGSV-NAHILH-EEELIAISRKGQTIRTPL-SIGV-GR---GVRIMKMD
G-KVASAIVF--
>tr|A0A0G1GZI7|A0A0G1GZI7_9BACT DNA gyrase subunit A OS=Parcubacteria (Giovannonibacteria) bacterium GW2011_GWA2_44_13b GN=gyrA PE=3 SV=1
SEDLIPEEETILILTQGGYAKRIKPEEYKLQKRGG-G--IMA--ED-VAYEFIAGNSHDDLLFFTNSGKVYQTKMYEIPET-RQSKGKSIANFL-SSD-E
R--SVLPVP--GQTYSVILCTEAGVIKKVDSKDFED-R-SGIKAINLK--DTLHF---V---EEVVLSSKLGQAI------IRSMGRSAQGIRGMRLKS-
-VLVGMDIVT-KSEILSVSQLGYGKKTSI-QYK-QNRGGSGIKTS---TAKTGNV-SVQVVE-ATEIIAMSQKGQVIRAPL-QIPS-SR---GVRIMKLA
G-KVASVTVL--
>tr|A0A0G1FL46|A0A0G1FL46_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWB1_43_8b GN=gyrA PE=3 SV=1
DEDLIAQEETIITLSSGGYIKRVNPSVFKVQGRGG-G--ASD--DD-FLTHLVYARTHDNILFFTDNGKVYQTKVHEIPQS-RIAKGKIVHNFL-NTS-E
N--ALVAYD---EIKHLVMATAAGVVKKTLIEDFAN-R-SGIIAINLK--DSLKW---SD---QVIVITAKGQSI------LRPMGRSAAGVGGIKLKG-
-GVIGVDIIKSSKNLLVVSEQGFAKQTPL-EYK-QSRGGQGVKTA---SSKTGNV-ACKIIG-EKETIVLSAKGQIIKTKL-DIRQ-SR---GVRVMRVK
--KIVAITCL--
>tr|A0A0G1IDV2|A0A0G1IDV2_9BACT DNA topoisomerase (ATP-hydrolyzing) (Fragment) OS=Parcubacteria (Giovannonibacteria) bacterium GW2011_GWB1_44_23 GN=UW49_C0003G
AEDLVPEEETILILTQGGYVKRIKPDEYKVQRRGG-G--IVT--ED-VAYDFISGNTHDDLLFFTNLGKVYQTKMYEIPET-RQSKGKAVANFL-SAD-E
K--SALPVP--GQASYVVLCTQKGIIKKVDAKDFDD-R-SGIRAINLQ--DTLRF---V---EEIVLSSKLGQAI------IRATGRTAQGIRGMRLKS-
GGIVGMDILPVKLEILSVSQLGYGKKTLI-QYR-QRRGGSGVKTC---TPKTGNV-SVQVAK-QQEIIAISKKGQVIRAPL-QIPS-SR---GVRIMKLN
G-S---------
>tr|A0A0F5HW02|A0A0F5HW02_9BACI DNA gyrase subunit A OS=Bacillus thermotolerans GN=gyrA PE=3 SV=1
DEDLIPREQVILTLTHNGYVKRIPASTYRSQKRGGRGIQGMGT-EDDVVEQLMTTSTHDTILFFTNKGKVYRLKGYQIPEFSRTAKGIPIVNLLDVEK-E
WVNTMIRID--VQANYLFFATKSGIVKRTSLKEFTH-RTNGIRALTLREEDELISVR-TDG-KHIIVGTKQGMLIRFEE--VRQMGRASMGVKGIRLD--
GDVVGMELLAENDYVLVVTENGYGKRTPEEEYRIQSRGGKGLKTCNIT-SKNGPLVAVKTVTE-EDLMLITVGGVLIRMDVNDISITGRNTQGVKLIRLG
-ETVATVTKIE-
>tr|A0A0C2XVD6|A0A0C2XVD6_BACBA DNA gyrase subunit A OS=Bacillus badius GN=gyrA PE=3 SV=1
DEDLIPREQIVLTLTHNGYVKRLPASTYRSQKRGGRGVQGMGT-EDDFVEHLLTTSTHDTILFFTNKGKVYRLKGYQIPEFSRTAKGIPLINLLEVEK-E
WVNAMIRVE---ADAFLFFATKSGIVKRTQLKDFAN-RTNGLRALNLKEDDELISVR-TDG-KHIVIGTRDGMMIRFEE--VRQMGRVSTGVKGIRLS--
GDVVGMELLHENDYVLIVTENGYGKRTPEQDYRIQTRGGKGLKTCNIT-SKNGPLVAIKTVSE-EDLMLITVGGVLIRMDVNDISITGRNTQGVKLIRLH
-ETVATVTKIA-
>tr|I8AKN5|I8AKN5_9BACI DNA gyrase subunit A OS=Bacillus macauensis ZFHKF-1 GN=gyrA PE=3 SV=1
DEDLIPRTNIVITLTNKGYIKRLPISTYRSQRRGGRGVQGMGT-EDDFVEHLFTTVSHNTILFFTNKGKVYRLKGYEIPEMSRTAKGIPIVNMLQVER-E
TISAVIPVE---DDWYLNFMTKHGITKRSPLSQFAN-RKGGLFAITLRDEDELMGVK-TNG-KDIIVGTNNGMAIRYRE--VRSMGRTAAGVKAITLG--
NDVIGMEVLDETQEVLIVTDKGFGKRTPMEDYRLQSRGGKGIKTCNIT-DRNGQIIALKTVTE-EDLMIITADGILIRMNIDGISSMGRNTQGVKLISMN
-GHVATVAVVE-
>tr|R7P4M4|R7P4M4_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:609 GN=gyrA PE=3 SV=1
DESLIPEENILVVLTNKGYIKRTTSDTFKSQNRGGVGIKGMST-DEDFVEHMINLSTHDYILFFTDKGKVYRLKGYEIPES-RQSKGIPIVNLLQIEKDE
RVNAVIQITE--NSKYLLFATEGGVVKKTLISEFDNIRNSGKICISLRENDKLIDVKKTTGSDLVLLGSDAGRMVKFN---IRVMGRTASGVRGITL---
-KCICSEIV--DDTILLVTEKGYGKQTKVSEYRQTKRGSKGVKAMNITE-KNGNLVSVKIVH-GKELVIMTNSGMTMRMPLDQISV-GRVTQGLRLINLK
-NKVSTISLVD-
>tr|R6BL55|R6BL55_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:524 GN=gyrA PE=3 SV=1
DESLIPQEDIIITLTNKNYIKRIPKDTYKVQNRGGVGIKGMTT-EEDFVEQLISLNTHDYILFFTNKGKVYRLKGYKIPES-RTAKGLPIVNLLSLEK-E
KINTMITIN---TYKCLLFSTKNGLVKRTLISEFDN-RQSGKIAITLKDNDELISVR-TTG-DQIFICSSNGRMARFDE--IRIMGRTASGVRGINLK--
-DCVGTEVSEP-KMLLVVTENGYGKKTTMDEYRETKRGSKGVKTLNIT-E-NGRIVGFKST-N-KDLMIITENGIIIRMSVDAISQMGRVTKGVRLINLK
NN-VASISILD-
>tr|R5TTN0|R5TTN0_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:710 GN=gyrA PE=3 SV=1
DESLIPVERTLIALTHKGYIKRMLLDTYRTQNRGGVGIKGMST-EEDYVEKMINMSTHDYILFFSNKGKVYRMKGYEIPES-RQSKGLPIINLLPLENDE
KITSMIQVES--SNKYLMFFTKDGLTKRTRIEEFENIRNNGKKAIVLKDNDELISVRKTTGENEILIGASNGRMVRFN---IRVMGRSSSGVKGISF---
-YVVGAEVV--DEDVLIVTEKGYGKKTNVDQYRLTHRGSKGVKALNVTE-KNGNLVSLKTVK-DEDLLIITNSGIIIRIDTQQIST-NRNTQGIRLINLK
-NKVSTVALVE-
>tr|R6GS97|R6GS97_9FIRM DNA gyrase subunit A OS=Firmicutes bacterium CAG:582 GN=gyrA PE=3 SV=1
DESLIPQEDIIVTISDKGYIKRCASSTFKSQHRGGVGIKGMTT-EEDYVKYLVNASTHDYILFFTDKGKVYRIKGYEIPES-RQAKGLPIINLL-QEKGE
KINSIISIS-E--SEYLMFATKNGLVKKTPVGEYSNIRTSGKIAISLKDDDELIDVKVSDGNNKVILGSTSGRMVVFN---IRPMGRTASGVKGINLD--
-SCTGMEVGKDDDNLLIVTKLGYGKKTLISEYR-TKRGSKGVKALNVTD-KNGEMIAHKIVN-KKDLLMITESGMTIRMGIDQIS-LGRVTQGVKLINLK
-NYVSTISILD-
>tr|R7KHF7|R7KHF7_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:451 GN=gyrA PE=3 SV=1
DESLIPVEDIIVTLTNKGYIKRMKSDTYRAQNRGGVGIRGMST-EEDFVEQVIPMKTHDYLLFFSNSGKVYRLKGYEIPES-RQSKGIPIVNLLSLDKNE
NIRSMVELDD--KIKYLLFTTKNGLVKRTPIEEFNNIRKSGKISIILKENDELIAVRKTTGTDEVVIGAKNGRMVRFN---IRSMGRGTSGVKGIDL---
-EVVSSEII--GEEILIVTEKGYGKKTLIDEYRLTHRGSKGVKALNITE-KNGNMVALKYVNNKLDVMIITDSGIIMRMPLSQIST-KRTTQGNKLINLK
-NKVATIAIVE-
>tr|R6ZDP3|R6ZDP3_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:433 GN=gyrA PE=3 SV=1
DESLIPVEDIIVTLTNKGYIKRLTTDTYKVQNKGGVGVKGMST-EEDFVEKMVTVKTHDYILFFSNKGKVYKIKGYEIPE-SRQAKGLPIINLLPIEKDE
KINSILRIS---NSDYITFVTRKGLVKRTKIEEFDSIRKSGKIAITLKEDDELLFVTKTDGNNEIVIGSSNGRLVRFN---IRVMGRTASGVKGIEIP--
-ICVSAEK-V-TSDILIITENGYGKRTNIEEYRLTHRGSKGVKALNVTE-KNGNLAAVKNVN-DEELMIITNSGIIIKIPMNQVSK-SRVTQGVRLINLK
ENKVTTIATTK-
>tr|R6BHM9|R6BHM9_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:533 GN=gyrA PE=3 SV=1
DESLIPEENIIVTVTKNGYIKRCTSDTYKIQNRGGVGVKGMST-DEDFVEYLLNLSTHDYIMIFTNKGKVYRLKGYEIPES-RQSKGLPIVNVLPVEKDE
KISSIKKLNN--QEKYLILATKQGLIKRTNLEEFENIRATGKICIKLKENDELIGVKKTNGESNILLASSEGRMNVFD---IRVMGRTASGVKGINL---
-KCVSIETV--DDNIVIVTENGYGKKTLISEYRKTKRGSKGVKALNITE-KNGNIASIKKVI-DSDIMIITNQGIIIRLPLEQVSQ-GRVTQGTRLINLK
-GKVSSVSLVQ-
>tr|R5LMX9|R5LMX9_9MOLU DNA gyrase subunit A OS=Mycoplasma sp. CAG:877 GN=gyrA PE=3 SV=1
DESLIPNEDVIVTLTRNGYIKRLRTDTYRTQNRGGVGVNGMTI-EEDFVEHLISMKTHDYILFFSNKGRVYRMKGYEVPES-RQSKGLPIINLLQLDKDE
NISSIVEISS--EIKYLVFTTKNGVVKRTDISEFDSIRKSGKIAIVLKENDELISVRKTCGNNEIAIGANNGRMVRFP---IRPMGRSSSGVKGIDL---
-YVVGAEVV--GQTILIVTDKGYGKKTVIDEYRLTHRGSKGVKALNVTD-KNGMMVALKCIDSEYDVIIVTDNGTLMKMPLEQVST-KRATQGVKLINLK
-DKVATVAIVT-
>tr|R5JAX0|R5JAX0_9FIRM DNA gyrase subunit A OS=Firmicutes bacterium CAG:822 GN=gyrA PE=3 SV=1
DESLIPVENIVVTLTNKGYIKRMNSETYRTQNRGGVGIKGMTT-ENDFVEKIISMSTHDYLMFFTNKGKTYRIKGYEVPQS-RQSKGLPIINLLPFDKDE
EVTAMLKID---ENNNIVFCTQKGLVKRTAISEFENIRKSGKLAISLKENDQLISVKKTSGNDEIVIAASNGRMIRFN---IRVMGRTASGVKGIDL---
-ICVGCEIA--NQEILVVTEKGYGKRTNIEEYRMTHRGSKGVKALNITD-KNGNIVSFKLVS-DEDLMIITDSGIIIRLPIGQIST-GRVAQGVRLIHLK
-NKVSSIALLD-
>tr|R5VNP4|R5VNP4_9FIRM DNA gyrase subunit A OS=Coprobacillus sp. CAG:605 GN=gyrA PE=3 SV=1
DESLIPEENVMLALTSKGYIKRTTADTFKSQNRGGVGVKGMTT-EEDNVEHLINLSTHDYALFFTNKGKVYRLKGYEIPQ-SRQSKGLPIINLLQIEKDE
LVNSVIKVS---ENKYLMFATKGGIIKKTSLAEFESIRQNGKICITLRDNDELIAVRKTTGSDNILLGSSDGRMVKFN---IREMGRTASGVKGINLS--
-YCIGAEV-T-DNNILIVTENGYGKQTNVQDFRETRRGSKGVKALNVTD-KNGKLCTFKVVD-STDVVIITDSGMVMRMPLAQISV-GRVTQGVRLINLK
DGKVSTISLIK-
>tr|R7NED2|R7NED2_9MOLU DNA gyrase subunit A OS=Mycoplasma sp. CAG:776 GN=gyrA PE=3 SV=1
DESLIPEENVLIAMTNKGYIKRTTSDTFKTQKRGGMGIKGMTT-DEDFVENIINISSHDYVMFFTNRGKVYRIKGYEIPEN-RQSKGLPIINLLPLEKEE
TISSILGISE--DIKYLLFVTKQGLVKKTAIEEFSNIRTSGKICINLKENDELIAVKPTNGNNYILLGSETGRMVKFK---IRAMGRTASGVKGINL---
-KCICAEIV--EDKILLVTVKGYGKKTLVSDFRETSRGSKGVKALNITD-KNGNIASVKVVE-DKELVIMTNIGTTMRMTLDQINT-GRVTQGVRLINLK
-EFVTTFSLVE-
>tr|R5MC68|R5MC68_9MOLU DNA gyrase subunit A OS=Mycoplasma sp. CAG:956 GN=gyrA PE=3 SV=1
DEALIPEENIVVALTNKGYIKRTTSDTFKSQNRGGVGVKGMTT-EEDFVEHLVDLSTHDYLLFFTNKGKVYRLKGYEIPQG-RQSKGLPIINLLQIDKDE
RISSVIKIS---DKKYLLFVTKCGIIKKTSLTQFENIRQNGKIAITLKENDELIAAKKTSGNDMVLIGSSEGRMVKFT---IRDMGRTASGVKGIDLE--
-IVVSAEVV--DDNILLVTENGYGKQTKVADFRQTRRGSKGVKALNITD-KNGKIADFKVIG-ANDVIIVTNSGMIMRMPISQISV-GRITQGVRLINLK
-GKVSTITLIK-
>tr|R5HSA9|R5HSA9_9MOLU DNA gyrase subunit A OS=Acholeplasma sp. CAG:878 GN=gyrA PE=3 SV=1
DESLIPVEDIVITLTNKGYIKRMTSETYRTQNRGGVGIKGMNT-EEDFVENILSLKTHDYLMFFTNKGKVYRMKGYEIPES-RQSKGLPIVNLLPLDKEE
VVKTMLTIN---ESKYIVFCTQNGLVKRTNVEEFESIRANGKLAINLKEDDELVAVKKTDGNCQILIASSNGRMIRFD---IRVMGRSAAGVRGIDV---
-IVVGCEIA--NEEVLVITENGYGKRTDINQYRQTHRGSKGVKALNVTE-KNGNIVCFKLVT-EEDLMIVTNNGIIIRMPLEQVST-GRVAQGVRLINLK
-NKVATVATIA-
>tr|I0XUD6|I0XUD6_9LEPT DNA gyrase subunit A OS=Leptospira licerasiae serovar Varillal str. VAR 010 GN=gyrA PE=3 SV=1
AEDLIADEEVVLQITYDQFVKRLPLDTFKRQRRGGKGIQGLSQ-REDVVKIMKTAMTHDNVMFFSNIGKVYMMKAYELPQASKEARGKSLKAIIGLGENE
TVSAIFTFR---KGKDLLLVTKNGFIKRVELSEFGNVKKSGIIAIGLRDGDQLIQVS-VEKGDNVMIFSANGLALRIE---IRAQGRTAQGVTGMRLSE-
-DIVGLSKVVEGDDIFLISENGYGKRLGFEEFGTKGRGGKGMAFLKVGE-KNGAAVAVSSVG-EDEIILVTQQGMVIRTEANQISKMGRTAVGVRVVDIK
-NKVQDCTVIR-
>tr|I4B8V7|I4B8V7_TURPD DNA gyrase subunit A OS=Turneriella parva (strain ATCC BAA-1111 / DSM 21527 / NCTC 11395 / H) GN=gyrA PE=3 SV=1
TEDLIQNENEVITISEGGYIRRMPLDTFKRQHRGGKGVISGG--KEDALKHVHFCQSLDYLLFFSTRGKVFYMKAYEVPEATKDARGKHIKGFLSLGADE
VVTVIRS---FEK-KYLLMLTRLGIIKKLELSQISNAKKGGVMAMQFKAKDYLVDVA-VDDKDDIFMATAEGAGLRTNL--MRPQGRAASGIIGMTLE--
-DMSGLDVVRGKSFLLVVSESGYGKRVKYDEFGSKGRGGKGMAFF--TK--TGKAVAIRTVTEDAEVIVTTLSGMVLRSEVKQIALQGRTASGVRVVDIT
-GKVADMTVYI-
>tr|A0A068EX37|A0A068EX37_9LEPT DNA gyrase subunit A OS=Leptospira sp. GIMC2001:Bairam-Ali GN=gyrA PE=3 SV=1
AEDLISDEEVIVQLSEDMFIKRLPVDTFRKQKRGGKGIQGSSV-RDDFIKKVVTAMTHDNLMLFSNKGRAFNMKVYEIPIASKEARGKSLKAVINLGEDE
VITSLYQYR---D-SALLMVTRQGFMKKILLNEFSNTKKSGIIALGLRDGDTLIDVS-TKSNEDVFIGTRNGLAIRMN---LRSQGRTAQGVTGMRLSD-
-DIAGVTIVKPDSSLFVLSEYGYGKRTSYDEFSTKGRGGKGMTYVKVGE-KNGKSVGIATVS-NDEILVITQSGMAIRTPAKDVSIIGRTAVGVKVVDTK
-DGVIDFAVIS-
>tr|S3UTP6|S3UTP6_9LEPT DNA gyrase subunit A OS=Leptospira fainei serovar Hurstbridge str. BUT 6 GN=gyrA PE=3 SV=1
AEDLIADEEIVIQITYDQFVKRLPIDTFKRQRRGGKGIQGLSQ-RDDVVKIMRSAMTHDSVMFFSNIGKVYMMKAYELPQASKEARGKSLKAIIGLGESE
YISSVFTFR---KGKDLLLVTRRGFIKRVELSEFGNVKKSGIIAIGLRDGDELITVS-VIKGDDVMIFSRKGLALRIE---IRAQGRAAQGVTGMRLGD-
-DIVGLSKVVEGDDIFVISENGYGKRLGFEEFSTKGRGGKGMAFLKVGE-KNGSAVGVSSVG-DDEIILVTQQGMVIRTEANQISKMGRTAVGVRVVDIK
-NRVQDCTVIG-
>tr|I0X5Y9|I0X5Y9_9SPIO DNA gyrase subunit A OS=Treponema sp. JC4 GN=gyrA PE=3 SV=1
VEDMIKDEDMVVMISRLGYIKRVSVSKYKKQGRGG-G--NTN--DD-YIKQLFIGSTKDYLLFITNLGRAYWIRLHEIPEE-KASRGAHIKGLLSI-D-E
E--TVVSLK----SQYLFMITSEGTVKRVCTSEFTN-R-KGIIGIKLH--DKLVS---TA---EVMMISRRGKAL------VREMGRASCGIKGMKLS--
-GIAAAVKVE-DSSMILVTEKGYGKRVSF-NFN-HGRGTGGQRIF---TDSKGEI-GALDIK-KDELVFMTSQGKTLRLKA-DIKE-GA---GVTLVKVN
P-YLVGIDKIQ-
>tr|H7EI19|H7EI19_9SPIO DNA gyrase subunit A OS=Treponema saccharophilum DSM 2985 GN=gyrA PE=3 SV=1
AEDMIRKEDVVVTISKFGYIKRLPLTLYKSQARGG-G--GMN--DD-YVTQIFVATTHSYITFITSEGRAYWIRVHEIPES-RASRGTNIKSIL-QNN-E
E--AIVVMS--TDSQYIFMATQNGIVKKCKTTEFAN-K-RGVIAINLN--DKLVS---TS---DLMLITRKGQAL------VRPMGRSSTGVTGIRLSD-
-DLAAAIRVE-ATNALVVTERGVGKRVEF-DFN-HNRGTGGQRIF---TGCKGEI-GAMAVS--DEIVCITSLGKSIRVKA-SIPL-GR---GIKVINIT
P-FVVGFDKIS-
>tr|A0A0Q5QKF6|A0A0Q5QKF6_9ACTN DNA gyrase subunit A OS=Williamsia sp. Leaf354 GN=ASG12_01530 PE=4 SV=1
DEDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVQGA-GKQDDIVRHFFVCSTHDWILFFTTKGRVYRAKAYELPEANRTARGQHVANLLAFQPEE
RIAQVIQIK---AP-YLVLATRGGLVKKSRLVDFDS-RSGGIIAVNLRG-DELVGAQ--SSSDDLLLVSTKGQSIRFSE--LRPMGRQTSGVQGMRFN-D
-DLLSLNVVVESTYLLVATAGGYAKRTAMDDYPVQGRGGKGVLTIQYD-RRRGELVGALIVDN-SEVYAITSNGGVIRTLAKQVRK-GRQTKGVRLMNLD
-GTLLAIARNA-
>tr|A0A0M3TBK1|A0A0M3TBK1_9ACTN DNA gyrase subunit A OS=Corynebacteriales bacterium X1698 GN=gyrA PE=3 SV=1
DEDLIPEEDVVVTITETGYAKRTKTDLYRSQKRGGKGVKGA-TKQDEIVKHFFVCSTHDLILFFTTKGRVYRLKAYDLPEANRTARGQHVANLLAFQPGE
RIAQVIQLK---AP-YLVLATRNGLMKKSRLEDYDS-RTGGLVAINLKG-DELVGAS--SEDDDLILVSEYGQSIRFHD--LRPMGRATSGVYGMRFN-D
-DLLSMNVVK-NEFLLVATSGGYAKRTAMDDYPVQGRGGKGVLTIQYD-RRRGNLVGAEVVSD-DEIFAITTGGGIIRTAAKEVRK-GRQTKGVRLMNLS
-GSLLAIARNA-
>tr|D5UPB2|D5UPB2_TSUPD DNA gyrase subunit A OS=Tsukamurella paurometabola (strain ATCC 8368 / DSM 20162 / JCM 10117 / NBRC 16120 / NCTC 13040) GN=gyrA
DEDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVKGA-DKQDDIVRHFFVCSTHDWILFFTTKGRVYRAKAYELPEQSRTARGQHVANLLAFQPEE
RIAQVIQIK---AP-YLVLATKNGLVKKSRLEDFDS-RSGGIVAINLRD-DELVGAA--SSEDDLLLVSKNAQSIRFSE--LRPMGRATSGVQGMRFN-D
-DLLALNVVQEDTYLLVATSGGYAKRTAMDDYPVQGRGGKGVLTIQFD-PKRGDLVGALIVNE-TELYAITSGGGVIRTAARQVRK-GRQTKGVRLMNLG
-GTLLAIARNA-
>tr|Q8EX46|Q8EX46_MYCPE DNA gyrase subunit A OS=Mycoplasma penetrans (strain HF-2) GN=gyrA PE=3 SV=1
DEDLIPVENIVISRSANNYLKRISIETYKIQRRGG-G--KVS--DD-EVDDIITTTTHTDILFFTDFGKVYRIRAHEIPPS-RQSKGVPALNLM-NEN-E
K--VMLPVE--SK-GFLFLATTKGIVKRTSLSEYNS-K-NGKRAITLR--DQLLS---TD---EIYLGASNGLLT------VRVMGRTASGVKGINIEVA
DTVVGASS---GDLILSIGEKGLGKLSEA-NYR-TRRGSKGVVTL---NDKTGKI-FSSAVK--EEILIVTSSGKIIRQEL-NLRV-GR---GVTLVKLQ
K-KIIS-AAVY-
>tr|G4ELS7|G4ELS7_MYCIO DNA gyrase subunit A OS=Mycoplasma iowae 695 GN=gyrA PE=3 SV=1
DEDLIPQEDVVISMSANNYLKRIPIDTYRLQRRGGVGVKGVNT-NDDTVDDIITTTTHTDLLFFTDTGKVYRIRAHEVPVT-RQAKGVPAVNLINIEKNE
KILVMLPID---SKGFLFLATVNGIVKRTSLSEYNSIRSNGKIAITLREGDKLLSAFVTRGKDEIYLGASNGLLARFN---VRIMGRTASGVKGINIQ--
-VVVGASCS--GDLILSIGEKGLGKISEAENYRLTRRGSKGVVTLKQND-RTGKMVFSSAVK-DEDILIVTSSGKIIRTSLSKLRI-GRSTSGVTLVKLQ
-NKIVSAALFR-
>tr|T0C2H8|T0C2H8_9DELT DNA gyrase subunit A OS=Bacteriovorax sp. BAL6_X GN=gyrA PE=3 SV=1
IEDLVASEEMIVTITHKGYVKRMPLDTYKAQKRGGKGVKGAA--EDDFFTNIFTANTHDKLLFFTSRGQVFSKKVYEIPEGTRTSKGRNIANLI-QPSGD
RVTEIICVP---NEKYLIFATNKGLVKKTALEEYSNVKQSGLIAIKLQDGDHIVNVR-NDGSKDILLCSSAGKIIRFDT--ARPMGRVSQGVKGININ--
-EIIGMELIDD-MEILSVTSQGYGKRTESSQYRKQTRGGKGILAM--TK--NGEIVQIKPVTDKDDLMIITDRGQVVRTKVSGVSLMGRATQGVRLIKPK
-GKVVSIAKII-
>tr|T0RAR4|T0RAR4_9DELT DNA gyrase subunit A OS=Bacteriovorax sp. Seq25_V GN=gyrA PE=3 SV=1
LEDLVKEEETIVTITHKGYIKRMAIDTYKAQKRGGKGVKGAV--DDDFFTNIFTANTHDTMYFFTSRGQVFSKKVYNVPEGTRTSKGRNIANLI-QPGGD
KINEIICVP---SKLYLIFATKQGLVKRTSLEDYKNIKQSGLIAIKLQDGDSIANVR-SDGTKDVLLCASTGKIIRFDE--ARPMGRVSQGVKGINID--
-EIVGMELIDD-VEILSVTENGYGKRTISSEYRKQTRGGKGILAM--TK--NGDIIQIKPVTDKDDLMIITNKGQVIRTKIAGISLMGRTTQGVRIINLK
-DKVVAVEKMM-
>tr|T0T4J8|T0T4J8_9DELT DNA gyrase subunit A OS=Bacteriovorax sp. BSW11_IV GN=gyrA PE=3 SV=1
LEDLVKQEDVIVTITHQGYIKRLTLDTYKTQNRGGKGVKGAS--DDDFFTNVFVANTHSTILFFTNRGQVFSKKVYNVPEGSRTSKGRNIANLI-APSGE
TIKEIMCIP---DGKFLIMASEKGLIKKTDLSEYKKIKQSGIRAIKLQDGDSICSVR-SDGNKDVLLCSTSGKIIRFDE--ARPMGRVSQGVKGITLD--
-EIIGMELIDD-VEILSVTDNGYGKRTMSSQYRKQSRGGKGILAM--TK--TGDIIAIKPVTDKDDLMIITDKGQVIRTKISGISLMGRATQGVRLITVK
-QKVVSVEKIV-
>tr|E1X1M8|E1X1M8_HALMS DNA gyrase subunit A OS=Halobacteriovorax marinus (strain ATCC BAA-682 / DSM 15412 / SJ) GN=gyrA PE=3 SV=1
IEDLVKNEDVLVTITHKGYIKRMTMDTYRTQKRGGKGVKGASN-DEDFFTDIFTANTHSTILFFTNRGSVFSKKVYNIPEGTRTAKGRNIANLIPVPP-D
KIKEIMCIP--REGKYLMFATEKGLVKKSALTDYNN-KQSGLRAIKVQDGDSVCSVR-SDG-KDVLLCSTSGKIIRFDE--ARPMGRVSQGVKGINID--
ERIIGMELID-SVEILSITENGYGKRTAASQYRKQTRGGKGILAMRLT-D-NGEIKQIKPVSK-DDLMVITDKGQVVRTKISGISLMGRATQGVRIIKLK
-GSVVSVEKIV-
>tr|A0A0D5NIZ6|A0A0D5NIZ6_9BACL DNA gyrase subunit A OS=Paenibacillus beijingensis GN=gyrA PE=3 SV=1
DEDLIPREDVVITITHSGYVKRLPVSTYRSQKRGGKGVIGMGT-DDDFVEHLFVSNTHHFLLFFTNKGKVYRLKAYEIPDLSRTARGTPIINLLQIEQ-E
TVNAVIPVE---PDRYLFFGTRQGVVKKTPLDDYSN-RKVGLIAINLRDDDDLISVK-TDG-QEIIMGTAQGMSIRFPE--VRSMGRSATGVKGIQLD--
-DVIDMDVVAPDRDILIVTSKGYGKRTPESEYRIQSRGGKGIKTLNVT-E-NGTIAGLKVVEG-EDLMIMTETGTMIRTSMEGISTMGRNTQGVKLINIR
D-AVATVTRVA-
>tr|E0I977|E0I977_9BACL DNA gyrase subunit A OS=Paenibacillus curdlanolyticus YK9 GN=gyrA PE=3 SV=1
DEDLIPREDVIISITHSGYVKRLPVTTYRSQRRGGRGVIGMDT-DDDFVEHLFVSNTHHYLLFFTDKGKVYRLKAYEIPDLSRTARGTPIINLLQIEQ-E
VVNAVIPVE---NDKYLFFATRQGVVKKTPLDDYAN-RKVGLIAISLREDDDLISVK-TDG-QEIIMGTSQGMSIRFPE--VRSMGRSATGVKGIQLD--
-EVIGMEIVHPENDVLIVTSKGYGKRTPVNEYRIQSRGGKGIKTLNVT-D-NGTIVGLKVVED-EDLMIMTASGTMIRTSMDGISTMGRNTQGVKLINIR
D-AVSTVTRVA-
>tr|L0EIX5|L0EIX5_THECK DNA gyrase subunit A OS=Thermobacillus composti (strain DSM 18247 / JCM 13945 / KWC4) GN=gyrA PE=3 SV=1
DEDLIPREDVIISITHSGYIKRLPVSTYRSQKRGGKGVIGMET-EDDFVEHLYVSNTHHYLLFFTDKGKVFRLKAYEIPELGRTARGTPIINLIQIEP-E
TINAVIPIE---PDLYLFFATKQGIVKKTPLDDYSN-RKVGLIAINLREDDELISVK-TDG-REIIMGTSQGMSIRFPE--VRPMGRSATGVKGIQLE--
-GVIDMDVVDPEQDVLIVTAKGYGKRTPASEYRTQSRGGKGIKTLNIT-E-NGSVVSLKMVAD-EDLMIMTSAGTLIRTSIAGISTMGRNTQGVKLINIR
D-AVATVTRVS-
>tr|A0A0Q4QXI6|A0A0Q4QXI6_9BACL DNA gyrase subunit A OS=Paenibacillus sp. Leaf72 GN=ASF12_09320 PE=4 SV=1
DEDLIPREDVIISITHSGYIKRLPVTTYRSQKRGGKGVVGMDT-DNDFVEHLFVSNTHHYLLFFTNKGKVYKLKAYEIPDLSRTARGTPIINLIQIEQ-E
TINAVIPVQ---PNHYLFFATRQGVVKKTPLDDYIN-RKVGLIAISLREDDDLIGVK-TDG-QEIVMGTAEGMSIRFSE--VRSMGRSATGVKGIQLD--
-SVIDMDIVMNDNDVLIVTSKGYGKRTPMSEYRIQNRGGKGIKTLNVT-D-NGPIVSLKVVVD-EDLMIMTASGTLIRTSMEGISTMGRNTQGVKLINTR
E-TVATVTRIA-
>tr|J2ZKG9|J2ZKG9_9EURY DNA gyrase subunit A OS=Halogranum salarium B-1 GN=gyrA PE=3 SV=1
REELIPQEDVVVVVTEDDYIKRMPATTFRAQNRGGKGIIGTDL-EGDSVSSVFYANTHDYLLCFTNHGQVYQLKTYEIPEMSRTARGKSAVNVI-DDDGE
EIEAVVNTD--E-DEFFTMVTRDGYIKRTAVDDFSNILSTGIRAIRLEDGDALVDVE-TDGDRDIVIATEDGMSIRFDE--ARAMGRTARGVRGIQLT--
-DVAGVGAVG-HQWLLTVTKNGYGKRTDIGNYRTQSRNGKGLIDI--VR--NGPTCAIETVAPGDHLVAMSESGQIMRTRVDEISTVGRNTMGVIVMDLD
-GHVAAVDVVP-
>tr|M0N3F6|M0N3F6_9EURY DNA gyrase subunit A OS=Halococcus salifodinae DSM 8989 GN=gyrA PE=3 SV=1
REDLIPDEEVIVVMTENDYIKRMPASEFDAQGRGGKGIIGTKL-DGDRVSAVFRANTHDYLLAFTNQGYVYRLKVYEVPEMGRTARGKSAINLV-DEDGE
DITAVVATD--E-EECLTMVTREGYVKRTCATDFENIHSNGLIATRLEEDDELIDVE-TDDDGDLLIATQRGMAIRFPK--AREMGRSARGVNGIKLT--
-DVAGLVAAGDDADLLTVTENGYGKRTPMGEYRTQSRYGKGLKDI--NR--NGRVCTVEAATADDDLVVMSEGGQIMRTRVGDISTVGRNTMGVTVMDLE
-GHVACVDVLP-
>tr|E7QUS8|E7QUS8_9EURY DNA gyrase subunit A OS=Haladaptatus paucihalophilus DX253 GN=gyrA PE=3 SV=1
REDLIAEEDVFVVVTEQDYVKRMPIEQFDAQGRGGKGIIGADV-EDDTVSKVFRANTHDYLLCFTNHGQVYRLKTYEIPEMSRTARGKSAVNILDLDKGE
DITAVIT---F-EDESLSMVTQQGYVKRTAAKEFENILSTGIIAARLEDGDKLVDVK-TDGTKDLLVSTKNGMTIRFDE--AREMGRSARGVHGIRLD--
-DVVGMVAANG-DDLLTVTRRGYGKRTKLTEYRSQSRNGKGLIDI--GR--NGHVTEIKTVIEDDHLVLMSERGQIMRIRAEDISEVGRNTMGVTVMDVD
-DRVASVDVIP-
>tr|A2U0L8|A2U0L8_9FLAO DNA gyrase subunit A OS=Polaribacter sp. MED152 GN=gyrA PE=3 SV=1
IEDMIPDTKVVVTISNAGYLKRTNLDEYKVQNRGGRGQKGATT-NEDFLEHLFVGTNHQYMMFFTQKGKVFWMRVYEIPEGGKNTKGRAMQNLINIEQDD
SVKAFLVTQK--NSHYVIMATKKGQVKKTSLEQYSR-RTNGINAITIKEGDELLEAKLTTGDSQVMLALASGKSIRFE---TRPMGRTASGVRGITLQE-
-DVIGMVAVNDESNILVVSEKGYGKRSSLE-YRITNRGGKGVKTLNISE-KTGNLVAIKNVD-SNDLMIINKSGLVIRMAVEDLRVMGRATQGVRLINIK
-DSIAAVAKVV-
>tr|D0DPT2|D0DPT2_9LACO DNA gyrase subunit A OS=Lactobacillus jensenii SJ-7A-US GN=gyrA PE=3 SV=1
DEDLIEKQNVLLTLTHNGYIKRMPVSEFRTQNRGGRGIKGMGV-DDDFIERLTYSSTHDYLLFFTNKGKVYSKKAYEIPEYSRIAKGLPIINLLQL-DGE
KIQAMINVP---EEGNLFFITKMGVVKRTSVEEFSN-RNSGLIALTLRDGDELSNVL-TDG-QNIIIGTHLGYAASFKE--VRVMGRSAAGVRGINLR--
-NVIGSEVLKPGAEVLVISENGYGKRTAVSEYPIKGRGGKGILTTKVG-K-NGRLAGMTVVDT-TDIMLITTDGIMIRFKTEDVSQTGRATMGVRLIKLG
G-SVASLTAVP-
>tr|V5P1F5|V5P1F5_LACJH DNA gyrase subunit A OS=Lactobacillus johnsonii N6.2 GN=gyrA PE=3 SV=1
DEDLIEQKDVLLTLTHNGYIKRMPADEFKVQNRGGRGIKGMGV-DDDFINHLIFSSTHDFLLFFTNLGKVYSKKAYEIPEFGRNAKGLPIVNLLEL-DGE
KIQAVINVP---DDNYLFFVTKMGTVKRTKVSEFQN-RRSGLIALTLRDGDELNNVL-TDG-QNILIGTHLGYAVTFNE--VRSMGRTAAGVRGINLR--
-NVVGSDILEPDSEVLVISEKGYGKRTAASEYPVKGRGGKGIKTANIT-E-NGPLAGVTVVND-EDIMLITSAGVMIRFDVDDVSQTGRATLGVRLIKVD
G-QVASITAVP-
>tr|A0A0C1WBB1|A0A0C1WBB1_9CYAN DNA topoisomerase (ATP-hydrolyzing) OS=Scytonema millei VB511283 GN=QH73_28610 PE=4 SV=1
EFRIPNSEEVALEFTQKGYVRRLAVNGN-----KP-R--PSDN-ND-FVIQTAATKTDENLVVFTSGGKVYPLQVGDIPPS-GRSRGTPLISLLPGST--
---TQMLLP--E-NIQALFMTQLGRVKRLAASELQN-T-RGLTVVKFK--DRLLG---E----FLILASAGGRLL------LPILGRTAMGMQGLRLR--
-QMVGGVAIDDKTNLLLVTQEGYAKRIPA-VLR-GNRGDIPTQAL--AKS---DL-GIVSAT--SEVALLTSNQRIVRLPV-KIGK-GK---GDRLREIK
N-KIISVIAIP-
>tr|K9XAG2|K9XAG2_9CHRO DNA topoisomerase (ATP-hydrolyzing) OS=Gloeocapsa sp. PCC 7428 GN=Glo7428_0924 PE=4 SV=1
L-DVQPVEEVVLEFTQRGYVKRSP-NGQ-----RG-R--SAEN-YD-CVIQTQSAKTDQTLLVLTSSGKVFPVQVGEIPAV-RGERGSPLIGLLPNSA--
---AQFLLP--E-TTQLVLLTKLGKIKRLAMTEFLS-T-RGLTIIKFK--DELLS---Q----NLVLATIGGRLL------LPIMGRTAVGLQALRLR--
-QLVGGVVLDNGNNVLLVSQSGAAKRVSA-TLR-GNRGDIGTQAM--TKS---DL-GMVLAT--DEAALVTNTQRVVRIPI-KVTV-GK---GDRIAELN
G-KVIEVVAID-
>tr|K9S7H9|K9S7H9_9CYAN DNA topoisomerase (ATP-hydrolyzing) OS=Geitlerinema sp. PCC 7407 GN=GEI7407_1678 PE=4 SV=1
VEEAIAEEEMVLEFTHRGYVQRRSPKAFQRQQRSEAG--I-EL-DD-FTVQTVQARSNQELLVLTRGGKAYTLDVGDIPPT-RRSKGTPVIALH-EAP-D
A--SQIVLP--LSDRYLIMLTAQGRIKRLPLSDLSR-T-RGLTALKLK--DELAY---Q---LQMVLATSGGRML------LPIMGRTAQGAPGARLRR-
-QIVGCVAVP-GSKVILMTERGYSKRLPI-TLR-GNRGDIGMPAL---ESK-TDL-SIISAT-GPVLMALTSGDRLLRLPV-TIPV-NK---GDRVIQTK
D-RIVWLGAIA-
>tr|E5XVC8|E5XVC8_9ACTN DNA gyrase subunit A OS=Segniliparus rugosus ATCC BAA-974 GN=gyrA PE=3 SV=1
DEDLIAQEDVVVTITETGYAKRTKTELYRSQKRGGKGVQGA-AKQDDIVAHFFVCSTHDWILFFTTRGRVYRIKAYELPDMNRAARGQHVANLLALQTEE
KIAQVIHLR---AP-YLVLATKRGLTKKSRLTEFDS-RSGGIVAVNLKD-DELVGAA--SADDDLLLVSEHGQSIRFHE--LRPMGRATSGVLGMRFN-D
-DLLAMNVVRDGAYLLVATSGGYAKRTDLGEYPAQGRGGKGVLTVQYD-RRRGGLVGAVIVDD-TELYAITSGGGVIRTAARQVRR-GRQTKGVRLMNLA
-GRLIAVARND-
>tr|B8GGZ1|B8GGZ1_METPE DNA gyrase subunit A OS=Methanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c) GN=gyrA PE=3 SV=1
REDLIEDKPVLISITTQNYIKRLPLETYRMQRRGGRGVIGMAT-DEDSVEDIFVASMHDYLLCFTTDGRVYWLKVYNIPEASRTSKGKAIVNLL-EQD-E
LITAVIPIR---HDRYLLFSTEQGQVVKVPQDQFSRPRSTGINAISLRENDSLVDVK-TDGTKELILSTRKGQSLRFHE--VRTVGRNASGVRGIKLK--
--VQAATV---KDHLLTITELGYGKRTEFDEFRGHGRGTMGVRNI--AQ--NGVVA-TKAVSSDDEIVVMSALGNVIRMKVSDISVQKRSARGVRIIRLD
-DRVVGLAVLQ-
>tr|A3CVD7|A3CVD7_METMJ DNA gyrase subunit A OS=Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1) GN=gyrA PE=3 SV=1
REDLIEDKPVLVSLTSSNYVKRIDLDTYRNQRRGGHGVIGMAT-DNDGVEKVFVANMHDNLLCFTDRGRMYWLKIYDLPEGQRTGKGKALVNLLNLDG-E
RVTTVIPVR----DHHLFFATRNGTVAKMALDEFSR-RQTGINAINLRDGDALVDVK-TDG-QELILTTKFGQSLRFHE--VRPVHRNAMGVRGIKLR--
DALQAIAIVE-DDHLLTITEQGYGKRTEFDEYRGHGRGTLGVRNIVVD-A-AGNVVGSMAVSD-DEIIVMSASGIVIRTKVSEISIQKRGTRGVRVMKLD
-GRVIGFTILD-
>tr|J0SB03|J0SB03_9EURY DNA gyrase subunit A OS=Methanofollis liminatans DSM 4140 GN=gyrA PE=3 SV=1
KEDLIEDKPVLVSLTATNYIKRMPLEAYRMQHRGGKGVIGMAT-EDDVVSDVFVASTHDYLLCFTNKGRIYWMKVYDIPESSRTAKGKAIVNLLNLNDE-
LVSAVIPLR---TGEYLFFATKEGMVVKIPVEEFSRPRPSGILAIKLKEGDELMDVK-TDGSTEVLLTTWKGQSLRFSE--VRPLHRNSQGVIGIRMR--
-DLVSLSLVSK--HLLTITAGGMGKRTEFDEFRGHGRGTMGVRNI--AY--GDGVVAAKAVSDDDEIILMSTAGNVIRMTVGGISIQKRGTRGVRLMKMD
-GRVVGFAAIN-
>tr|A0A0N8W6B4|A0A0N8W6B4_9EURY DNA gyrase subunit A OS=Methanolinea sp. SDB GN=APR55_07260 PE=4 SV=1
TEDMIENKKVLVSLTSENYIKRMDLDTYRQQRRGGRGIIGMST-EGDYVESVFVANTHDYLLCFTNNGRVYWLKVYNIPEGSRTSRGKAIVNLLNLSKE-
KVTTVIPVS---QDRFVFFATRRGMVLKVPVVELSRPRSTGINVINLKENDELVDVK-TDGSREVILTTRKGQSLRFHE--VSQRHRNAMGVIGIRMK--
-DLRAITLVEK--HLLTVTEAGYGKRTDFDEFRGHGRGTMGVRNI--EH--HGGVVAAKSVSDDDEVILMSASGIVIRTQVSGISIQKRSTRGVRIMKME
-GRVVGVAVLV-
>tr|A7I8T9|A7I8T9_METB6 DNA gyrase subunit A OS=Methanoregula boonei (strain 6A8) GN=gyrA PE=3 SV=1
TEDLIEDKTVLVSITTANYIKRMDLDTYRKQRRGGHGITGMTT-EDDVVSSVFAAGMKDYLLCFTNIGRVYWLKVYQIPESSRIAKGKPIVNLLNLKDEV
VTT-VIPIR---KDRYLLFATQLGQVIKIPQDEFSFPRSTGTNAIRLRENDKLVDVITTDNTKEVVLSTRFGYGLRFHE--VRIVGRGASGVIGMRLR--
-TIVALTLVEK-DHLLSITDAGFGKRTEFDDFRGHGRATMGVKNM---E-RDV-VIHSRAVADTDEIFVMTASGVVIRTSVNSIRITGRGAKGVKIMRLD
-KKVIGVAIVT-
>tr|L0HHJ9|L0HHJ9_METFS DNA gyrase subunit A OS=Methanoregula formicica (strain DSM 22288 / NBRC 105244 / SMSP) GN=gyrA PE=3 SV=1
TEDLIEDKAVLVSITSANYIKRMDIDTYRKQRRGGHGITGMTT-EEDLVDSVFTASMKDYLLCFTNNGRVYWLKVYQIPESSRIAKGKPIVNLLNLKDEV
VTT-VIPIR---ADQYLIFATKLGQTIKIQLDEFSNPRSTGTNAIRLKDNDRLVDVILTGGNNELILTSRFGQSLRFHE--IRIVGRNAQGVRGMKLK--
-TIVAITLLEK-DHLLTISDVGFGKRSEFDEFRGHGRGTMGVRNM---E-RDAVVIESRAVLDTDEIIAMTASGIVIRIPVSEFRIIGRGTKGVRVMKLD
-KKVVGIAVVS-
>tr|H4GIG5|H4GIG5_9LACO DNA gyrase subunit A OS=Lactobacillus gastricus PS3 GN=gyrA PE=3 SV=1
DEDLIEEEEIIVTLTHSGYVKRLPVDEFKSQNRGGRGVKGMGV-NDDFIEHLISSSTHDSLLFFTNSGKVFAMKGYEIPEYGRSAQGIPIINLLGI-NDE
QISAVINVST-DDDRDLFFVTKEGTVKRTSVNEFKN-RSNGLKAINLHEGDELIHVE-IDQ-QAMILGTRLGYSVSFKA--VREMGRSAAGVRGVRLR--
-GVIGAAQLSPDSNVLVISEQGYGKQTPATEYPIKGRGGKGIKTVNIT-E-NGPLVGLTTVQD-EDLMLATNKGVIIRFSVESVSVTGRSAIGVHLIKMN
D-VVATMAKVD-
>tr|A0A0R1UPS9|A0A0R1UPS9_9LACO DNA gyrase, A subunit OS=Lactobacillus equigenerosi DSM 18793 = JCM 14505 GN=FC21_GL001183 PE=4 SV=1
DEDLIEEEEIIVTLTHNGYVKRLPVDEFKSQNRGGRGVKGMGV-NDDFIEHLIASSTHDRLLFFTNSGKVFTMKGYEIPEYGRAAQGIPIINLLGI-NDE
QISAVINVSA--DDLDLFFATKQGTVKRTAVSEFNN-RSNGLKAINLHDGDELIHVD-IRP-DNLILGTHLGYSVSFNA--IRQMGRAAAGVRGARLR--
-NLIGAAKLTPNSKVVVISERGYGKQTPASEYPIKGRGGKGIKTANIT-E-NGPLVGLTTVND-EDLMVVTNNGVIIRFGVENVSTTSRATIGVHLIKMN
D-VVATMAKVA-
>tr|C0WVU3|C0WVU3_LACFE DNA gyrase subunit A OS=Lactobacillus fermentum ATCC 14931 GN=gyrA PE=3 SV=1
DEDLIEEEDIIVTLTHNGYVKRLPVDEFKAQNRGGRGVKGMGV-SDDFIEHLVASSTHDLLLFFTNTGKVFAMKGYEIPEYGRAAQGIPIINLLDV-DKE
KVTAVINVA--DLQKDLFFVTRQGTVKRTLVTEFKN-RSNGIKAINLHEGDELINVA-VDD-QNMILGTHLGHAATFKV--VRSMGRSAAGVRGARLR--
-GLIGAAPLNEDDQVLVISEKGYGKKTPASEYPIKGRGGLGIKTVNVT-E-NGPLAGLTTVQD-EDLMVVTDKGVIIRFGVESVSQTRRSAIGVHLIKMD
D-VVATMTKVE-
>tr|A0A072NJY8|A0A072NJY8_BACAZ DNA gyrase subunit A OS=Bacillus azotoformans MEV2011 GN=gyrA PE=3 SV=1
DEDLIPEQSIVISLTHKGYIKRLPADTYRSQRRGGRGVQGMGT-EDDFVEHLLSTSTHNTILFFSNKGKVYRLKGYEIPEFSRTAKGIPIINLLEIEK-E
WINAVIPVE---DDWYLFFATKQGVVKRSPLSSFAN-RKGGLIALHLREGDEVISVG-TDG-REIMIGTKNGMLIRFNE--VRSMSRLATGVKGINLN--
DDVIGMEIIEGKEDVLVVTRHGYGKRTPLSEYRMQSRGGKGIKTCNIT-EKNGPLSAIKAVTE-EDLMLITESGIVIRMAVDTISITGRNTQGVKLMRLD
-NVVSTVAKVD-
>tr|N4WQQ4|N4WQQ4_9BACI DNA gyrase subunit A OS=Gracilibacillus halophilus YIM-C55.5 GN=gyrA PE=3 SV=1
DEDLIPEENIVITLTHQGYIKRLPASTYRAQRRGGRGIQGMGT-EDDFIEHLVSCSTHDTVLFFSNKGKVYRAKGYEVPEFNRTAKGIPIINMLEIEQ-E
WINAVISVQ---EDWNLVFTTKYGISKRTSLIQFAN-RKGGLIALNLRENDELISVR-TDG-KDMLIGTKYGYVIRFEE--IRTMGRTAAGVKGISLR--
NDVVSMEIVEEGEYVLNVTDNGYGKRTPIEDYRITNRGGKGIVTCHIT-EKTGEVVAVKTVSE-EDIMIMTISGVLIRMQVEGISTTGRNTQGVRLIRLQ
-GKVATVAKVD-
>tr|K2GAT6|K2GAT6_9BACI DNA gyrase subunit A OS=Salimicrobium jeotgali GN=gyrA PE=3 SV=1
DEDLIPEETIVVTLTNQGYVKRLPADTYRAQRRGGRGVQGMGT-DEDFVEHLLSTSTHSTVLFFSNKGKVYKLKGYEIPEFSRTAKGLPIINLLNIEN-E
WINDVIAVD---EDWYFVFTTRHGVTKRTSLSKFAN-RKGGLIALSLRENDELISVR-TDG-KDIMIATRNGYLIRFPE--IRSMGRTAAGVKGISLR--
DDVVSMELVEDDREILTVTDKGFGKRTPASEYRITNRGGKGILTCNLT-ERNGKVVSTKAVTE-EDLMIMTASGVLIRMAAGSVSRTGRNTQGVRLIRLQ
-GEVSTVARLE-
>tr|C8PS29|C8PS29_9SPIO DNA gyrase subunit A OS=Treponema vincentii ATCC 35580 GN=gyrA PE=3 SV=1
IEDLIKKEQMVVLVSNLGYIKRVPVTAYKRQNRGGKGSNSAAL-EDDFIDQIFTASTHDYIMFITNEGKAYWVKVHEIPEASRTSRGSHIKSLLAVSSDE
EITTIVSL----SDTYLLMATAGGIVKKVQTDSFQNAKTRGIIAIKLDEGDKLVSAILTTGKDELMLVTRQGQALRVSE--IRDQGRASHGVIGIRLS--
-ELTGALRIN-NGKLLVMSENGYGKRVDFSEFSPHGRGTGGQKVY--TE-KTGEVVGLLAVADDDEIVCITGQGKTIRVQVSSINVMGRAAQGVRILDIE
-PQLIGLDVVA-
>tr|A0A0H3BJF4|A0A0H3BJF4_TREPS DNA gyrase subunit A OS=Treponema pallidum subsp. pallidum (strain SS14) GN=gyrA PE=3 SV=1
VEDFIQKEEMVILISHLGYIKRVPVSAYRNQNRGGKGSSSANL-AHDFISQIFTASTHDYVMFVTSRGRAYWLKVYGIPESGRANRGSHIKSLLMVATDE
EITAIVSLR---NKSYVFMATARGVVKKVTTDNFVNAKTRGIIALKLSGGDTLVSAVLVQDEDEVMLITRQGKALRMSG--VREMGRNSSGVIGIKLT--
-LVAGVLRV--QRKVLIMTENGYGKRVSFSEFSVHGRGTAGQKIY--TD-RKGAIIGALAVLDTDECMCITGQGKTIRVDVCAISVLGRGAQGVRVLDIE
-SLVVGLSCVM-
>tr|S3K2Y2|S3K2Y2_TREMA DNA gyrase subunit A OS=Treponema maltophilum ATCC 51939 GN=gyrA PE=3 SV=1
IEDLIKEEDMVILISHLGYIKSIPVTAYKNQGKGGKGSNSAKL-EDDYIKQLFVASTHDYIVFISTEGKAYWIKVHEIPEAGRASRGSHIKSLLAIGANE
EIATVVSL----EEQHLFMATANGVIKKVKTADFKNAKTRGIIAINLDAGDKIVSAILTGGSDDLALASRRGKVLRITE--VRPMGRSSRGVSGLKLA--
-ELTAAVRVDTNANMLLVTESGYGKRVDFDQFSVHSRGTQGQIGY--ND-KTGEVVGVIAVADTDEVMCITSQGKTLKLAASAISQQGRASQGVCILKID
-PFVIGVDRVE-
>tr|S3L319|S3L319_TREDN DNA gyrase subunit A OS=Treponema denticola SP23 GN=gyrA PE=3 SV=1
IEDLIKKEEMVILISHLGYIKRIPATAYKSQNRGGKGSNSVNL-EDDFLDQIFTASTHDYIMFITNAGKAYWLKVHEIQEASRTSRGSHIKSLLSVSSDE
EITAVVSL----DKTYLLMATAGGVVKKVTTDNFANAKTRGIIAIKLDEGDKLVSAILTGGKDEIMLITRRGQALRTSE--IRSQGRSSRGVTGIKLS--
-ELTGALRVTENQKMLVMTENGYGKRVEFSEFSAHGRGTGGQRIY--SE-KTGEVVGLLTVFDDDEVVCITGQGKTIRISVDSVGTMGRSAQGVRILDIE
-PMLIGLDVVA-
>tr|F4LP13|F4LP13_TREBD DNA gyrase subunit A OS=Treponema brennaborense (strain DSM 12168 / CIP 105900 / DD5/3) GN=gyrA PE=3 SV=1
IEDLIKEEEMVILISNLGYIKRIPLTAYKAQGRGGKGSNSAKL-EDDFINQIFIASTHDYIMFITNEGKSYWLKVHEIPEAGRNSRGAHIKGLLTVSPNE
EITTVVSL----DEQYLFMATAAGVVKKVQTSQFSNAKTRGIIAIRLDEGDKLVTAILSGGTDELILISRRGQALRITE--VRPMGRAGRGVGGLKLA--
-ELAGALRVESDACMMLLTEKGFGKRVDFDEFAAHGRGTGGQRIY--SD-KTGEIVGTINAADSDEIVCITSQGKSLRVAANSVTKQGRSASGVRVFNID
-PMVIGLDRVA-
>tr|F2NXS7|F2NXS7_TRES6 DNA gyrase subunit A OS=Treponema succinifaciens (strain ATCC 33096 / DSM 2489 / 6091) GN=gyrA PE=3 SV=1
VEDLIKEEDMVILISKLGYIKRVSVSQYKSQGRGGKGTISAKL-EEDYINQMFVASTHDYLMFITTEGKAYWIKVHEIPEASKTSRGSHIKSLLAVNANE
DITTIVSL----ENNYLFMATANGVVKKTPTSDFKNAKSRGMQAVRLDEGDTLVSAILSTGKDELLLVSRRGQALRINE--VRPMGRSSRGVAGLKLS--
-ELCSAIRIHTDSKILVVTEKGIGKRVDSAEFNAHGRGTGGQKIF--VE-DKGEIIGALCVRDTDSIMCITSQGTSVRVEAKDITVQGRGASGIKVVSIT
-PYVVGVDRIA-
>tr|S3JLC3|S3JLC3_TRESO DNA gyrase subunit A OS=Treponema socranskii subsp. paredis ATCC 35535 GN=gyrA PE=3 SV=1
VEDMIKQEDVVILVSKLGYIKRLAATQYKSQGRGGKGSFSANL-EDDYINQIFIASTHDCIMFITNEGKAYWIKVHEIPEASKMSRGSHIKSLLAVSADE
EITTTVTVK---GDNYVLMATTNGVVKKTALSDFANAKTKGVIAIKLDGGDKLVSAILTAGKNDVFFVSRRGKALRISE--VRPMGRASRGTRGMKLA--
-EIAAAVRA--GKSIMLVTEKGFGKRINPEDFKSHGRGTGGQRCY--TE-ERGEIIGALAVADGDEVLCITSQGKTLRVAAGDIKEQGASSTGVSVVKVD
-PYLVGIDRVA-
>tr|E7NQS3|E7NQS3_TREPH DNA gyrase subunit A OS=Treponema phagedenis F0421 GN=gyrA PE=3 SV=1
IEDLIQKEEMVILISNLGYIKRIPVSAYKSQNRGGKGSNSANL-EDDFIDQIFTASTHDYIMFITNEGKAYWLKVHEIPEASRTSRGSHIKSLLSVSGDE
EITAVVSL----DSTYLLMATAAGVVKKVTTDNFQNAKTRGIIAIKLDDGDKLVSAILTTGKDEIMLITRHAQALRMTE--IRPLGRASRGVAGIKLA--
-ELTGALRVADNQKMLIMTENGYGKRVEFSEFTPHGRATGGQRIY--SE-KTGEVVGLLTVLDDDEVVCITGQGKTIRVNVDSISIMGRSAQGVRVLDIE
-PILIGLDVVA-
>tr|A0A0G2B8T9|A0A0G2B8T9_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWB1_55_9 GN=gyrA PE=3 SV=1
TEDLVPDEDSMLVVTQGGYVKRTNPSEYKKQKRGG-G--VIA--ED-IVTHFLVTSAHSDLLFFTTFGKAYQLKMYEIPEK-RATKGKSIMNFL-PSD-E
A--SVLAVP--LDASSVVFVTEQGVAKRVAAKSFAG-R-SGIIAINLK--DTLVS---AD---TVSIVTAKGQSI------VREMGRTAGGVRGMSVKK-
-GVVSAEVIPAEQSLLVVMSKGYGKRTKL-EYK-QGRGGSGIKTA---TPKTGEI-GARVVS-EEELVVVSKKGQVIRCAV-EIPS-GR---GVRVMKLY
G-SIASMVAL--
>tr|A0A0L0LPA5|A0A0L0LPA5_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium C7867-001 GN=gyrA PE=3 SV=1
IEDMVPDEESVLVITAGGYVKRTNPNEYKAQKRGG-G--IMS--ED-VVTHFLSTSAHSDLLFFTDYGKVYQTKMYDIPER-RATKGKSIMNFL-PAD-E
K--SVLPVPR--AALSVVLVTDAGVVKKVEAKNFAD-R-SGIIAINLK--DRLVS---A---DSVSIVTSAGQSI------VRAMGRTAAGVRGMSVKG-
-YVVSAEVIPAKAALLVVMEKGYGKHTDM-EYK-QGRGGSGIKTA---TAKTGKI-GAKVLA-VEEIVVISKKGQVIRVSA-EIPS-SR---GVRIMKMR
G-SIASMVAL--
>tr|A0A0L0LBE7|A0A0L0LBE7_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium C7867-004 GN=gyrA PE=3 SV=1
MEDLVPDEESVLVLTAGGYVKRTNPEEYKIQKRGG-G--IMS--ED-VVTHFLKASAHSDLLFFTDYGKAYQMKMYELPEK-RATKGKSMMNFL-QAE-E
K--SVLAVPQ--EALSVFFVTQEGVVKKVAAKSFAD-R-SGIIAIALK--DKLVS---A---DSISIVTAKGQSI------TRAMGRVAAGVRGMSVKG-
-RIVSAEVVPAGAALLIIMEKGYGKKTPL-EYK-QGRGGSGIKTA---TAKTGDI-GAKVLI-VEELVVISKKGQVIRCTT-EIPS-SR---GVRVMKMR
G-SIASMVAL--
>tr|A0A0G1YKQ5|A0A0G1YKQ5_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWA1_56_13 GN=gyrA PE=3 SV=1
AEDLVPDEDSMLVLTAGGYVKRTNPSEYRRQKRGG-G--VIA--ED-IVTHFLVASAHSDLLFFTNFGKVYQLKMYDIPEK-RATKGKSIMNFL-PAE-E
S--SVLAVPL--NASSVVFVTEAGAVKRVAAKNFAD-R-SGIIAINLK--DTLVS---A---DTVSIVTAKGQSI------VREMGRTAGGVRGMSVKG-
-TIVSAEIIPGDASLLVIMSKGYGKRTKI-EYK-QGRGGSGIKTA---TPKTGEI-GARVII-EEELVVISKKGQVIRTSV-EIPS-GR---GVRVMKLR
S-SIASMVAL--
>tr|A0A0G1RNH2|A0A0G1RNH2_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWA2_47_12 GN=gyrA PE=3 SV=1
DEDLIPDEESVLVFTRGGYVKRTDPEEYRKQKRGG-G--VLD--ED-FVVSTLSASTHSDLLFFTDRGKVYQMKMYEIPEK-RATRGKSIANFL-AAD-E
R--SILPMPAL-AGLALIMVTKNGIGKKVAAERFHD-R-SGLIAISLK--DELIS---V---DECAVVTSGGQSI------IRAMGRGAGGVRAIKLRG-
-IVAGAQVVKKKAALFILSEHGYGKATLF-EYK-QKRGGSGIKTA---TTKTGKI-AARVLS-EEEVIAISKKSQVIRIAA-EIPR-GR---GVRIMRLR
G-GIASVTVL--
>tr|A0A0L0LHG9|A0A0L0LHG9_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium C7867-008 GN=gyrA PE=3 SV=1
VEDLVADEESVLVLTAGGYVKRTNPDEYKIQKRGG-G--VIA--ED-VVTHLIGASAHSELLFFTDFGKAYQIKMYEIPER-RATKGKSIMNFL-QAD-E
K--SVLPVPR--DALSVFFVTQEGVVKKVESKNFAD-R-SGIIAIALK--DKLIS---C---DSISIVTAQGQSI------VRAMGRTAAGVRGMSVKG-
-RVVSAEVVNSG-ALLIIMDKGYGKKTSL-EYK-QGRGGSGIKTA---TTKTGQI-GAKVLV-MEELVVISKKGQVIRVAA-EIPS-SR---GVRIMKMR
G-SIASMVAL--
>tr|E9S9S5|E9S9S5_RUMAL DNA gyrase subunit A OS=Ruminococcus albus 8 GN=gyrA PE=3 SV=1
IEDLIPVEESVVTYTNVGYIKRMPISVYKAQNRGGKGVTGMKQ-EDDCVTEMSVCSSHDNILFITTKGQAYKMKCYELPES-KASRGVNIKNLLELSDDN
LIAAMIKVE-F-DDKYIVMVTKRGKIKRTPLSAYKNVRKRGLIAIGLDDGDEIAGVRLTEGNNELLIATHNGMAIRIS---VRVMSRTAHGVRAIKLR--
-YVVSMARIR-GASVLTVSETGLGRRVELESYPVRHRGGSGVLNYKNGD-----VCGIKVVD-D-DIIMISSDGIVIRLRACDISM-GRYSRGVRLMKVT
-DKVVTFTRTE-
>tr|K9WZG4|K9WZG4_9NOST DNA topoisomerase (ATP-hydrolyzing) OS=Cylindrospermum stagnale PCC 7417 GN=Cylst_3433 PE=4 SV=1
K-PEQPPEEAALEFTQRGYVRRIQ---------PT-K--PTEN-ND-FIIQTELTDTEKDLLILNSSGKVYPVRVGDIPAT-GRSRGTPLITMLTTTV--
---SRFLL---E-TDQMVLLTKQGRIKRLSMGEFTN-T-RGITILKLK--DELSF---T----HLILASSGGRLL------LPVMGRAAMGLQAFRLL--
-NMVGCVAVG-DDQLLLVTQEGSAKRMPA-QLK-ANRGDLGTQSL--AKT---DL-AMVRAT-GTEVALLTNKERVVRIPV-TVPI-GR---GESILQLS
D-KIISVVEVR-
>tr|A0A0P1BWR0|A0A0P1BWR0_9NOST DNA gyrase, A subunit OS=Chrysosporum ovalisporum GN=apha_01248 PE=4 SV=1
P-SALPVEEVVLEFSYRGYVRRLQ---------PS-K--SSEN-HD-FMIQTHLTTTDQELLVITSGGKVYPVTVGDIPPT-GRSRGTPLITMLSSTQ--
---SRLILS--E-AKQMVLLTKAGRIKRLSLAEFTN-T-RGITILKLK--DELLF---T----NLILASSGGRLL------LPVMGRTALGLQAFRLL--
-HMVGCVTEA-NDNLLLVTEEGYAKRLPV-HLK-AERGNLGTQAL--AKT---DL-GMVQSI-SGEVALVTNKERVMRIPV-TVPI-GR---GQSILDLN
D-RIVSVMEVE-
>tr|A0A0C2Q5B9|A0A0C2Q5B9_9CYAN DNA topoisomerase (ATP-hydrolyzing) OS=Tolypothrix campylonemoides VB511288 GN=SD81_29525 PE=4 SV=1
T-LVAPPEDVVLEFTHRGYVRR-Q---------PS-R--ATDN-ND-TVIQTVLTDTAKELLVLTSSGKVYPVNVADIPPN-GRSRGTPLITLLSNSQ--
---NRFVLP--E-DGEMVLLTKQGRIKRFSLTELTH-T-RGITILKLK--DELLS---K----HLILASSGGRVL------LPIMGRTAMGLQGLRVR--
-QMVGFVASS-KENLLLVTQLGYAKRMSV-ALR-ANRGDIGTQTF--SKA---DL-GMVRAT-GAEVALVTNHQRLVRLGV-TVPT-GK---GESILQLN
E-KIICIVELH-
>tr|D7E0L0|D7E0L0_NOSA0 DNA topoisomerase (ATP-hydrolyzing) OS=Nostoc azollae (strain 0708) GN=Aazo_2820 PE=4 SV=1
K-SEQPPEEAILEFTQRGYVRRLS---------PT-K--PAEN-ND-FIIQTELTDTEKDLLILNTGGKVYPVKVGDIPAT-GRSRGTPLITMLTSTV--
---NRFVLP--E-RSQMLLLTKQGRIKRLSMEEFAN-S-RGITILKLK--DELSF---T----HLILASSSGRLL------LPIMGRAAMGLQAFRLL--
-NMVGCATVG-DDQLLLVTQEGYAKRIPA-NLR-ANRGDLGIQML--HKT---DL-GMVRAT-GVEVALVSNKERVVRIPV-TVPI-DR---GESVLQLN
D-KIITVVEVG-
>tr|K9QTS9|K9QTS9_NOSS7 DNA topoisomerase (ATP-hydrolyzing) OS=Nostoc sp. (strain ATCC 29411 / PCC 7524) GN=Nos7524_2734 PE=4 SV=1
--FAEPAEEVILESTQRGYLRRIQ---------LS-K--ALDN-ND-FIIHTELTDTHKELLVLTSGGKLYPVKIGDIPPT-GRSRGTPLITMLTSTQ--
---SRFILP--E-TQQIILLTKQGRIKRLSLGELTN-T-RGITIVKLK--DELLL---K----HLILASSGGRLL------LPVMGRTAMGLQALRLL--
-HMVGCVSAA-AEHLLLVTEQGYAKRLPV-QLK-ANRGDLGTQAL--TNT---DL-GMVGAI-TTEVALVTNKERVVRIPI-AVPI-AR---GESILQLN
D-KVITVAEVR-
>tr|A0A0C1RHK0|A0A0C1RHK0_9CYAN DNA topoisomerase (ATP-hydrolyzing) OS=Tolypothrix bouteillei VB521301 GN=DA73_0217035 PE=4 SV=1
K-LSVPAEDVVLEFSHRGYVRRLQ---------PS-K--PAEN-ND-FIIQTVSTDTEKEVLALSSGGKVYPVKVGDIPPN-GRSRGTPLITLLSSTQ--
---NRFVVP--D-T-DLVLLTKQGRIKRLSLTELTN-S-RGITVLKLK--DELLF---T----HLFVASSGGRVL------LPIMGRTAMGLQSLRLR--
-RMVGCVTCE-EENLLLVTQTGYAKRLSI-GLR-ANRGDIGTQVF--AKA---DL-AMVRAI-SSEVALITNHQRVVRLAV-TVAT-GR---GDKVLQLN
D-KVITVVPLH-
>tr|A0A0C2Q9Y0|A0A0C2Q9Y0_9CYAN DNA topoisomerase (ATP-hydrolyzing) OS=Scytonema tolypothrichoides VB-61278 GN=SD80_28925 PE=4 SV=1
K-LEAPAEEVVLEFTHRGYVRRSQ---------PS-R--TTDN-TD-LVIQSVLADTAKELLVLTSGGKVYPVNVADIPPS-GRSRRTPLITLLSNSQ--
---NRFVLP--E-NGEIILLTKQGRIKRLSLTELTN-T-RGITILKLK--DELLC---T----HLVLASSGGRVL------LPIMGRAAMGLQGLRVR--
-QMVGCVSLN-KENLLLVTQLGYAKRIPV-GLR-GNRSDIGTQTF--TKT---DL-GMVRAI-SAEVAVVTNHQRVVRLGV-TVPI-GK---GESILQLN
E-KIISVIELH-
>tr|A0A0M0SMB7|A0A0M0SMB7_9CYAN DNA topoisomerase (ATP-hydrolyzing) OS=Hapalosiphon sp. MRB220 GN=AMR41_13530 PE=4 SV=1
K-PEQPVEEVVLELTQRGYVRRIQ---------PN-K--SIDN-ND-FVMQTALTETDKDLLVLTSNGKVYPVKVGDIPPT-GRSRGTPLITLLTNTS--
---SRFLLP--E-DGEMILLTKQGRIKRLSLTEFTS-T-RGITILKLK--DELLL---T----QIILASSGGRLL------LPTMGRTAMGLQAMRLR--
-RIVGGVTFK-EENILLVTQLGYAKRLPT-ALR-ANRGDIGTQTF--AKT---DL-GMLIAK-GSEVALVTNHQRVMRLQV-TVTN-PK---GESVFELN
D-KIITVAELV-
>tr|G6FUN9|G6FUN9_9CYAN DNA topoisomerase (ATP-hydrolyzing) OS=Fischerella sp. JSC-11 GN=FJSC11DRAFT_2586 PE=4 SV=1
K-PKSPPEEVTLELTQRGYVRRLQ---------VN-K--PVDN-ND-FVMQTTLTDTDKDLLVLTSGGKVYPVKVGDIPPT-GRSRGTPLITLLTNTS--
---SRFLLP--E-NGEMILLTKQGRIKRLSLTEFTN-T-RGITILKLK--DELLL---T----QIILASSGGRLL------LPIMGRTAMGLQAMRLR--
-QMIGGATFD-EENILLVTQLGYAKRLPT-VVR-ANRGDIGTQTF--AKT---DL-GMVLAK-GSEVALVTNHQRVVRLQV-TVTN-AK---GESIVQLS
D-KITAVAEVA-
>sp|P47250|GYRA_MYCGE DNA gyrase subunit A OS=Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195) GN=gyrA PE=3 SV=1
DESLIKVENVVITMSTNGYLKRIGVDAYNLQHRGG-G--KLT--DD-SISQLLVCSTHSDLLFFTDKGKVYRIRAHQIPYF-RTNKGIPAVNLI-KED-E
R--SLLSVN--DD-GYFFFCTKNGIVKRTSLNEFIN-L-NGKRAISFD--DTLYS---TD---EIFIGSTNGFVV------LRVLSRTARGVFGISLNK-
-EVNGLST---GSLLLSVGQNGIGKLTSI-KYR-TKRNAKGVKTL---TDRTGPV-TTTTVF--EDLLMISSAGKIVRTSL-ELSE-GK---GVKLIRLK
N-RLER-VTIF-
>tr|A0A0K2F0R5|A0A0K2F0R5_MYCPM DNA gyrase subunit A OS=Mycoplasma pneumoniae PO1 GN=gyrA PE=3 SV=1
DEDLITQENVVITMSTNGYLKRIGVDSYNLQHRGG-G--KLT--DD-SISQLLVCSTHSDLLFFTDKGKVYRIRAHQIPPF-RTNKGIPAVNLI-KDD-E
K--ALISVN--QN-GYFFFCTKNGTIKRTSLSEFAN-L-IGKRAILFK--DVLFS---TD---DIFIGSTAGFVV------VRPLSRAAMGVLGINLNQ-
-EVNGLST---GSLLLSVGQNGIGKLTSI-KYR-TKRNAKGVKTL---TAKTGPV-TTTTVF--EDLLMISSAGKIVRISL-QLSE-GK---GVKLIKLK
K-RLET-VTIF-
>tr|A0A0G1CIU7|A0A0G1CIU7_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWA2_43_11 GN=gyrA PE=3 SV=1
PEDMIAEEESVLVITRGGYIKRTNPDEYKKQKRGG-G--ILN--ED-FVTIFLTASTHDDLLFFTDKGKTYQIKMYDVPEK-RATKGKSVMNFL-PSD-E
S--SVVAMTE--SDGSLLMVTKGGITKKTKAKDFHD-R-SGIIAIKLA--DKLIQ---V---DTVLLATKKGQSI------AREMGRAAAGVRGVKLGG-
-VVIGADIALKELSLLVVSENGYGKQTAL-EFK-QKRSGSGIKCA---TTKTGTM-ASRILT-IEELVVISKKGQVIRTDI-EIPS-GR---GVRIMKLR
G-SIAAIICL--
>tr|A0A0G4BBA3|A0A0G4BBA3_9BACT DNA gyrase subunit A OS=Parcubacteria (Campbellbacteria) bacterium GW2011_OD1_34_28 GN=gyrA PE=3 SV=1
VEDLIPEEESVLVYTSGGYIKRTNPDEYKRQKRGG-G--VLK--ED-FVTTFLTTSTHSDLLFFSDKGKAYQIKMYDIPEK-RATRGKSIMNFL-QEE-E
R--SILPMPQ--NNISLLMVTKAGVTKKVAAKNFHD-R-NGLIAIKLQ--DELIT---V---DTIILTSSKGQSI------VREMGRGAGGVTGMKLGG-
-FVVGGNIIKKNPDFFVMSGNGYGKKTSL-EYK-QKRGGSGIKTM---TDKTGNI-TSKVLT--QEIVAISKNAQVIRVDV-EIPS-GR---GVRIMKMR
G-KIASLTCL--
>tr|A0A0G1ZJL5|A0A0G1ZJL5_9BACT DNA gyrase subunit A OS=Parcubacteria (Kaiserbacteria) bacterium GW2011_GWB1_52_6 GN=gyrA PE=3 SV=1
AEDLIADEESVLVLTSGGYIKRTNPAEYRRQRRGG-G--VLD--ED-FVTQFLTASAHSDLLFFSDRGKVYQLKMYDLPEK-RATKGKSIMNYL-SES-E
N--SILAMPIV-EGLSLIMTTRDGTVKKSAANKFYE-R-SGLIAINLD--DALIS---V---DSVVLVTTKGLAI------VREMGRQAAGVRGMKLRG-
-AIVGTGVVPKDAELLVLSSTGYGKKTKL-EYK-QGRGGSGIKTM---TTKTKQV-GGAVLT--GELVAMSKKSQTIRTGL-EIPT-SR---GVRVMKMR
G-QVASFVVFE-
>tr|A0A0G2AS57|A0A0G2AS57_9BACT DNA gyrase subunit A OS=Parcubacteria (Adlerbacteria) bacterium GW2011_GWA1_54_10 GN=gyrA PE=3 SV=1
IEDMVADEEQVLTLTAGGYVKRTNPEEYRRQKRGG-G--ILN--ED-FVTTFLTTSTHSDLLFFTDVGKSYQLKMYDLPEK-RSTKGKSIVNFL-STN-E
K--SVLPMRE--GEKFLYMITKQGVAKKVDASSFRD-R-SGLIAIKLQ--DQLVA---V---DEIFLSTAKGQSV------VRAMGRAAGGVRAVRLRG-
-SIVGADVIPKDLEVLVVSRGGYGKTTPT-EYK-QKRGGSGIKTM---TAKTGPI-AARIVSKVNEIVVVSKKGQIIRASL-EIPS-SR---GVRVMKLR
Q-AIASFVCL--
>tr|A0A0F9YGA8|A0A0F9YGA8_9BACT DNA gyrase subunit A OS=Parcubacteria (Nomurabacteria) bacterium GW2011_GWF1_31_48 GN=gyrA PE=3 SV=1
DEDLIPDKETMLVFSAGGYVKRTDPIEYHSQKRGG-G--VLE--ED-FVTMLVSGSTHSDLLFFTNLGKAYQMKMYDIPER-RATRGKSIMNFI-ANE-E
K--SILPMP--KNGSSLMLITKNGSAKKMSSASFKD-R-SGIISIRLD--DSLVS---T---DDVMLATTGGQSI------IREMGRTAGGVRGIKLGG-
-EVIGVDVVRKDGSFLTMSANGFGKKTSL-EYK-QKRGGSGIKTA---TPKTGKI-VAKVLT--EELIAMSKKGQVIRTAL-DISS-GR---GVTIMRLR
G-SIASLVCA--
>tr|A0A0G0GXG4|A0A0G0GXG4_9BACT DNA gyrase subunit A OS=Parcubacteria (Nomurabacteria) bacterium GW2011_GWB1_37_5 GN=gyrA PE=3 SV=1
TEDLIPDKEAMLVYTQGGYVKRTDPAEFRVQKRGG-G--VLE--ED-FVTHLISANTHSDMLFFTNLGKAYQIKMYDLPER-RATKGKSIMNFL-SSD-E
K--SILPMP--KSSEAMILVTKKGTAKKVLAENFKD-R-SGLIAISLD--DELDA---V---DEVMLATSAGQSI------IRTMGRSAAGVRAMKLGS-
-SIIGVDIIRKDAQFLTMSENGLGKKTVL-EYK-QKRGGSGIKTA---TPKTGKI-VARVVT--KELIAISQKGQVIRTEL-SIPN-GR---GVTIMKLR
G-KIASLTCL--
>tr|A0A0G1HYS8|A0A0G1HYS8_9BACT DNA gyrase subunit A OS=Parcubacteria (Nomurabacteria) bacterium GW2011_GWF2_43_8 GN=gyrA PE=3 SV=1
DEDLVPEKETILVLTAGGYVKCTDPSEYRAQKRGG-G--ILE--ED-FVTMLVSGSTHSNLLFFTNLGKVYQMRMYDIPER-RATRGKSIMNFL-ASE-E
K--SILAMPGLKTTSSLMLITKHGTAKKMSSESFKD-R-SGIIAIRLD--DQLIS---V---DEVMIATAEGQSI------VREMGRTAGGVSGIRLRN-
-EVIGVDVIRKEGFFLTMSGNGFGKKTAL-EYK-QKRGGSGVKTA---TPKTGKI-VAKVLT--EELIAMSKKGQVIRTAL-DISA-GR---GVTVMRLR
G-GIASLACL--
>tr|A0A0K9GZI5|A0A0K9GZI5_9BACI DNA gyrase subunit A OS=Bacillus sp. FJAT-27997 GN=gyrA PE=3 SV=1
DEDLIPVETTIVTLTHKGYIKRLPVSTYRSQKRGGRGIQGMGT-EDDFVNHLLTTSTHDTLLFFTNKGKVYRAKGYEIPEYGRTAKGLPLINLLEVEK-E
WVNAIIPVK---DGDYLFFTTKFGISKRSPLSSFAN-RNNGLIAVGLNEGDELISVR-TDG-KQIVIGTKDGMLIRFPE--VRSMGRTAAGVKGISLR--
DDVIGMEILEESEEVLIVTKFGYGKRTPAEEYRIQSRGGVGIKTCNVT-DKNGELVAVKTVT--EDIMIITAEGVLIRMAVGDISTTGRNTQGVKLIRLE
TNFVATVAMAE-
>tr|A0A0H4KQZ9|A0A0H4KQZ9_9BACI DNA gyrase subunit A OS=Bacillus endophyticus GN=gyrA PE=3 SV=1
DEDLIPEQSIVITLTHNGYIKRLPVSTYKSQRRGGRGIQGMNM-ENDFVEQLLTTSTHDTILFFTNKGKVYRTKGYEIPEYSRTAKGLPIINLLKVEK-E
WINAIIPVK---DTDYLFFTTKDGIAKRTPLSSFEN-RTNGLIAINLREEDELISVR-TNG-QHMVIGTKKGLLIRFDE--VRSMGRTATGVKGITLA--
DDVVGMEISADEDDILVVTKNGYGKRTPVEDYRIQTRGGKGLKTCNIT-EKNGDVVALKSVND-DDLMLITVHGVLIRVSVEDISQTGRNTQGVKLIRLG
-DYVSTVARVQ-
>tr|A0A0G1RNM7|A0A0G1RNM7_9BACT DNA gyrase subunit A OS=Microgenomates (Amesbacteria) bacterium GW2011_GWC1_46_24 GN=gyrA PE=3 SV=1
EEDLIPSEDTVVTVTATGYIKRQNPTAFRTQHRGG-G--TQT--ED-EISHIITANTHDDILFFTNLGRVFKIKAYDLPES-RQAKGQAVVNLI-NGE-E
K--TILAMG--GASKFLLMATNKGTIKKSKLSDFDH-R-SGIIAIKLE--DNLKW---TD---QILLVSRNGKSI------VRPTARDTMGVRGIELKT-
-SVVGMEIFPGFEDVLIITERGLGKRTSV-LWP-QKRGGQGVKAA---TDKTGLI-ACIGVD-VDQIVLTSRSAQIIKLPL-NIPN-GR---GVILMRFS
K-FVAAVTCLE-
>tr|A0A0G1Q2Q1|A0A0G1Q2Q1_9BACT DNA gyrase subunit A OS=Microgenomates (Amesbacteria) bacterium GW2011_GWC2_45_19 GN=gyrA PE=3 SV=1
EEDLIPSEDTVVTITATGYIKRQLPSAFRAQHRGG-G--TMT--ED-EIAQILTANTHDNIYFFTNKGRVFRIKAYDLPES-RQSKGQAVVNLI-NED-E
R--TVLPLG--NGVKFLLMVTSLGTIKKTKISEFES-R-SGKIAIKLD--DALKW---TD---HVLLVSHEGKSI------VRATARDTTGVRGIDLKS-
-GVVGMEVFPSFEDVLIVMEHGLGKRTGV-QWP-QKRGGQGVKAA---TSKTGKV-ACISVD-IEQIILTAKSAQVIKLPL-NIPR-GR---GVILMRFA
K-SVAAVTCIE-
>tr|A0A0G1UC46|A0A0G1UC46_9BACT DNA gyrase subunit A OS=Microgenomates (Amesbacteria) bacterium GW2011_GWA1_47_16 GN=gyrA PE=3 SV=1
YEDLIPSEDTVITITSTGYIKRQNPSAFRTQHRGG-G--TMT--ED-EIAQLLTANTHDDILFFTSKGRVFKVKAFDLPES-RQSKGQAVVNLI-NPD-E
K--TVLSLG--DAYKFLLMTTHRGTIKKSKLSDFDH-R-SGIIAIKLE--DSLEW---TD---QVLIVSKEGKSI------VRPTARDTMGVRGIELKS-
-GVVGKEVFPAFEDVLIITEKGLGKRTSV-NWP-QKRGGQGVKAA---NDKTGKV-TCIGVD-VEQVVLTSRTAQIIKLPL-NIPR-GR---GVILMRLG
--SVAAVTYLD-
>tr|E4TPA1|E4TPA1_MARTH DNA gyrase subunit A OS=Marivirga tractuosa (strain ATCC 23168 / DSM 4126 / NBRC 15989 / NCIMB 1408 / VKM B-1430 / H-43) GN=gyr
DEDMIPNEDVVITLSHQGYIKRTLLNEYKTQGRGGVGSKGAGS-DDDFTELLFVAKTHNYLLIFTELGKVYWIKVYRLPEGSKTSKGRAIQNLINIESED
SVRAVINVED--NNNFLVMCTEKGTIKKTTLEAYSR-RANGINAISINEGDRLLNVKLTNGDNNIIIAARSGRAIRFH---VRPMGRTAAGVRGITLKG-
-DVVEMVAITRNANLLVVSEKGYGKRSDIEDYRITKRGGKGVKTLNVTE-KTGELVAIKEVI-SDDLMIINKSGITIRMAVESLRVMGRATQGVRLIKVN
-NSISSVEKVE-
>tr|L8K1L2|L8K1L2_9BACT DNA gyrase subunit A OS=Fulvivirga imtechensis AK7 GN=gyrA PE=3 SV=1
VEDMIPNDEMVITISHQGYIKRSPLVEYRTQSRGGVGSRGVST-DDDFTEHLFIARAHNYLLIFTAFGKVFWKKVYGIPEGSKTSKGRAIQNLINIEPGD
KVRAVINVET--DNNFVMMCTENGTIKKTSLKAYSR-RQNGINAITVRDGDRLLDVKLTNGDNHIVIAKRNGKAIHFH---VRPMGRTASGVRGVTLEA-
-DVVGMVCISRESNLLVVSEKGYGKRSLVEDYRITKRGGKGVKTINVTE-KTGKLVAIKEVV-SDDLMIINRSGITIRLAVSGLRVMGRATQGVKLIRLN
-NEISSVEKIE-
>tr|S2YB90|S2YB90_9FIRM DNA gyrase subunit A OS=Coprococcus sp. HPP0048 GN=gyrA PE=3 SV=1
TEDLIPEQDVVITMTKLGYIKRMTTDTFKSQNRGGKGIKGMQT-EEDYVEELFMTSTHNYIMFFTNTGRVYRMKGYEIPEAGRTARGTAIINLLQLMP-E
KITAMIPIR---DGKYLFMATKKGLVKKTPITDYAN-RKTGLAAITLREDDELIEVK-TDN-KDIIMVTKYGQCIRFKE--VRSTGRTSMGVRGMNLS--
-RVIGMQLHTQGDYLLIASEKGMGKRTAIEEFTCQNRGGKGVKCYKIT-E-TGNVIGVKAVND-NEIMIINTEGIVIRMECAGISILGRVASGVKLINLD
N-KVASIAKVR-
>tr|R6PNA7|R6PNA7_9CLOT DNA gyrase subunit A OS=Clostridium nexile CAG:348 GN=gyrA PE=3 SV=1
MEDLIPRQDVVITMTKLGYIKRMTVDTFKSQNRGGKGIKGMQT-DEDYVEELFMTSTHHYIMFFTNTGRVYRLKGYEIPEASRTARGTAIINLLQLMP-E
KITAMIPID---EGQYLFMATKKGLVKKTPITDYAN-RKTGLAAITLREEDELIEVK-TDQ-QDIILVTKYGQCIRFNE--VRATGRTSMGVRGMNLA--
-RVVGMQLHTQGTHLLIVSEKGMGKRTAMEEFTSQNRGGKGVKCYKIT-E-TGNVVGVKAVND-NEIMIINTEGIVIRMECNSISVLGRITSGVKLINLN
N-TVASIAKVR-
>tr|C6LKK8|C6LKK8_9FIRM DNA gyrase subunit A OS=Marvinbryantia formatexigens DSM 14469 GN=gyrA PE=3 SV=1
VEDLIPEENVVITMTRLGYIKRMTPDNFKSQNRGGKGIKGMQT-DEDNIEELFMTSTHEYLMFFTNLGKVYRLKAYEIPEAGRTARGTAIINLLQLAP-E
KITAVIPIR---EDHYLFMATKKGLVKKTPITDYAN-RKTGLAAISLREDDELIEVK-TDN-KDILLVTAYGQCIRFHE--VRSTGRVSMGVIGINLM--
-GVVGMQLDCQGEYMLIVSEKGMGKLTAMEEFKVQNRGGKGVKCYKIL-E-TGNVIAAKAVND-SDIMIINTEGIIIQMPCSDISVLNRITSGVKLMNLE
-DQVASITKVR-
>tr|A0A0K9NEH3|A0A0K9NEH3_9FIRM DNA gyrase subunit A OS=Dorea sp. D27 GN=gyrA PE=3 SV=1
MEDLIPRQDVVITMTKLGYIKRMSNDTFKAQHRGGKGIKGMQT-EEDYVEELFMTNTHHYIMFFTNTGRVYRLKAYEIPEASRTSRGTAIINLLQLMP-E
KITAVIPIE---EGEYLFMCTKKGLVKKTPITDYAN-RKTGLAAITLREEDELIEVK-TNN-RDIILVTKYGQCIRFNE--VRSTGRTSMGVRGMNLA--
-RVIGMQLDSQGTHLLIVSEKGMGKRTGMEEFTSQNRGGKGVKCYKIT-E-TGNVVGVKAVDD-DEIMIINTGGIIIRMKCDNISSLGRVTSGVRLINLP
G-TVASIAKVR-
>tr|A8F8Z0|A8F8Z0_BACP2 DNA gyrase subunit A OS=Bacillus pumilus (strain SAFR-032) GN=gyrA PE=3 SV=1
DEDLIPVENIVITLTHNGYIKRLPASTYRSQKRGGKGVQGMGT-EDDFVEQLISTSTHDTILFFSNKGKVYRAKGYEIPEFGRTAKGIPIINLLEVEK-E
WINAIIPVS---ENSYLFFTTRHGVSKRTTLSQFAN-RNNGLIALSLRDEDELMAVR-TNG-KQIIIGTKKGMLIRFDE--VREMGRTAAGVKGITLS--
DDVVGMEILEPDANVLIVTEKGYGKLTPEKEYRVQSRGGKGLKTCKIT-DNNGPLVAVKATNEEEDLMIITGSGVIIRMAVSDISTTGRVTQGVRLIRLG
E-HVATVALVE-
>tr|A0A0C1UEU1|A0A0C1UEU1_9CYAN DNA topoisomerase (ATP-hydrolyzing) OS=Hassallia byssoidea VB512170 GN=PI95_11300 PE=4 SV=1
K-SEEPVEEVVLEFSHRGYVRRTQ---------PS-K--PADN-ND-FIIQTAVTDTDKELMVLTSGGKVYPVNVGDIPPT-GRSRGKPLITMLSSTQ--
---NRFVLP--E-TSQMILLTKQARIKRLSLGEFTN-T-RGITILKLK--DELLF---T----HLIVASSGGRLL------LAIMGRTAVGLQALRLL--
-HMVGCVTFA-DSNLLLVTEEGYAKRIPV-EFK-ANRGDLGTQAL--KKT---DL-GMVMAI-SSEVALVTNRERVVRLSV-TVPL-GR---GESVLQLN
D-KIITVAQVY-
>tr|A0A0D8ZUK2|A0A0D8ZUK2_9CHRO DNA topoisomerase (ATP-hydrolyzing) OS=Chroococcales cyanobacterium CENA595 GN=UH38_15075 PE=4 SV=1
--KVEEKEEAVLEFSLRGYVRRLG-NGQKG---------K-NG-ND-CVVQVEVTNTGQDLLVLTGGGKVYPVGVGDVPLS-RASRGVPLVSLL-S-S-E
G--SQFLLP--IDAAGLVLVTRLGRIKRLALAELAG-S-RGLTAIKFK--DRLLA---S---DEAILATGGGRLL------LPVMGRTAVGLQALRLRK-
-NLVGCVTGA-EENLVLFSQLGYAKQMPL-SLR-ADRGGIGTQAL---SSK-ADL-SMVLVP-GAVL-AVTTDRRLLQVPI-AVSA-GK---GDRLSLLN
D-KIVSVTVLP-
>tr|B0BZD7|B0BZD7_ACAM1 DNA topoisomerase (ATP-hydrolyzing) OS=Acaryochloris marina (strain MBIC 11017) GN=gyrA PE=4 SV=1
FAAPVSDESVIVELNQRGYARCMRVSKRKNNA--PDG--L--A-TD-LTIFRHTTELTTDLLLFTGSGKAYGVGLQSIPFS-SKGKGKPLVTLL-PSD-D
E--ARFLST--SDTSQLILLSQQGKIKRLPMSEFAE-T-RGLGAAKIK--DQLGW---E---TNVAIATSSGRLL------IPEMGRTAQGNQVFRLRK-
-QIVGLAAVR-DADLLLISSKGYCKRLPI-LLR-GKVGDLGTQAM---MIK-SDL-ALLPAN-NQDVIVLSNQERAARLNI-TLPM-GQ---GTQLLKTK
G-VLENTVVIP-
>tr|B2IY50|B2IY50_NOSP7 DNA topoisomerase (ATP-hydrolyzing) OS=Nostoc punctiforme (strain ATCC 29133 / PCC 73102) GN=Npun_R6377 PE=4 SV=1
K-SSEPAEEAILEFTQRGYVRRTQ---------PS-R--SAEN-ND-FIIQTVLTDTQKDLLILTGGGKVYPVNVGEIPPT-GRSRGKPLITMLSNTQ--
---SRFLLP--E-TQQMILLTKQGRIKRLSLGEFTN-T-RGITILKLK--DELSF---K----HLILASSGGRVL------LPIMGRTAMGLQAFRLL--
-NMVGCVTVG-DDHLLLVTQEGYAKRMAA-QLR-ANRGDLGTQAL--AKT---DL-GMVIAI-SGEVALVTNKERVVRIPV-TVPI-GR---GESIIQLN
D-KIITVAEVR-
>tr|K9Q7K4|K9Q7K4_9NOSO DNA topoisomerase (ATP-hydrolyzing) OS=Nostoc sp. PCC 7107 GN=Nos7107_0430 PE=4 SV=1
P-IEQPAEEAILEFTQRGYVRRLS---------TS-K--PAEN-ND-FLIQTELTDTNKDLLILTSGGKVYPVRVGDIPLT-GRSRGTPLITTLTTTQ--
---SRFLLP--D-FKQMILLTKQGRIKRLSFAEFTN-T-RGITIVKLK--DELLF---N----HLILASSGGRLL------LPVMGRTAMGLQAFRLL--
-NMVGCATVG-DDHLLLVTQQGYAKRIAA-QLR-ANRGDLGTQAL--AKT---DL-SMVKAT--PEVALVTNKERVVRIDV-TVPI-GR---GEIILQLN
D-KIIAVAEVR-
>tr|A0ZJC1|A0ZJC1_NODSP DNA topoisomerase (ATP-hydrolyzing) OS=Nodularia spumigena CCY9414 GN=NSP_48880 PE=4 SV=1
P-DAEPPEEVILDFSHRGYVRRLQ---------PS-K--SAEN-HD-FIIQSDLTATDKELLVITSSGKVYPVNVGDIRPT-GRSRGTPLITMLSSTQ--
---SRLILP--E-TRQMVLLTKEGRIKRLTLGELTN-T-RGITILKLK--DELLF---T----NLILASSGGRLL------LPVMGRTAMGLQALRLL--
-HMVGCVTAA-EDNLLLVTEEGYAKRLPV-NLK-ADRGNIGTQSL--AKT---DL-AMVQAI-SAEVALVTNKDRVVRIPV-TVPI-AR---GESILDLN
D-RIISVMEVQ-
>tr|K9V2S7|K9V2S7_9CYAN DNA topoisomerase (ATP-hydrolyzing) OS=Calothrix sp. PCC 6303 GN=Cal6303_3068 PE=4 SV=1
K-LETPAEEVIVEFTHRGYVRR-Q---------PA-R--SIDN-ND-FIINTLQTETNQDVLVITSGGKVYPIGINEISPT-GKNRGTPLITLLTSTQ--
---NRFLLS-----QEMILLTKQGRIKRLAATELMG-T-RGATVLKLK--DELLL---N----QMIIASSGGRML------LPAMGRAAMGLQALRLG--
-QMAGGLALA-NDDFLIVTEEGYAKRMAV-QLP-ANRGDLGAQSL---KT---DL-GIVKTS-VPEIVLITNQQRIIKIPV-SIPI-TKYGGGLRILVPN
D-KVTTVMELK-
>tr|B8HNL0|B8HNL0_CYAP4 DNA topoisomerase (ATP-hydrolyzing) OS=Cyanothece sp. (strain PCC 7425 / ATCC 29141) GN=Cyan7425_1367 PE=4 SV=1
--ELAADTEVTLELSQRGYVRCLRGGERGRRNQAR-E--AANNKKD-LILYNPRAKLSDALLVFTQSGKGYRVDLTAMPLD-RRDKGVPLVTLLPES---
---AQFLCP--S-EQQLVLLSAEGRAKRISLEDFAE-T-RGLSVCKLK--DYLAW---D----EVAIATSTGRLL------IPLMGRTTLGQQAIRLH--
-QLVGAIVLQ-YDNLLLVSERGYGKRMPL-AVR-GRLGDLGTTAI--VKP---DL-AIAPAP-NAEVMLFTDKNRMANLSL-QIPI-GK---GKLLLNLE
G-KLTSASVAD-
>tr|A0A0D6L1F1|A0A0D6L1F1_9CYAN DNA topoisomerase (ATP-hydrolyzing) OS=Tolypothrix sp. PCC 7601 GN=FDUTEX481_00581 PE=4 SV=1
K-SEVPAEEAILEFTHRGYVRRIA---------VN-K--PTDN-ND-FIIQTQTTDTDKELLVLTSGAKVYPVRVGDIPAT-GRSKGTPLITLLSNTQ--
---NRLLLP--E-NTQMILLTKQGRIKRLALEELSN-T-R-VTILKLK--DELIY---T----HLIVASSSGRLL------LPIMGRAAMGLQALRML--
-QMVGCGVVS-QEELLLVTQEGYAKRLTA-QLK-ANRGDLGTQAL--TKT---DL-AMLVAI-SGEVALLTNKERIVRLPL-TVPF-DR---GQSVLQLN
D-KIISVVEVR-
>tr|H1HU61|H1HU61_9FIRM DNA gyrase subunit A OS=Stomatobaculum longum GN=gyrA PE=3 SV=1
AEDLIPDETVIVAMTNRGYIKRMNPDYFRNQARGGKGIRGMQT-EDDFITDLLMTTTHRPIDFFTNKGRLYRLKVYQIPDS-RTARGTAIVNLLQLQADE
KVTAMISYR-K--AKYLFMATKQGMVKKTELSAYMNVRSNGLAAIALREDDELIGVKASRGTEDVLLVTQNGQSILFS---VRVTGRNSYGVKGIALR--
-AVVAMQLTAQGEELLTVTAYGMGKRTELTEFH-QNRGGYGNLCHKLTD-KTGFLIGAKLVR-DQEMLLITNTGVMIRISVGDIS-YGRLASGVKLMNIE
-DRIAGIAMVK-
>tr|H9UMZ8|H9UMZ8_SPIAZ DNA gyrase subunit A OS=Spirochaeta africana (strain ATCC 700263 / DSM 8902 / Z-7692) GN=gyrA PE=3 SV=1
IEDLIQKQEMVVIMTRRGYIKRIPSNSYRTYKTTGVGSSSSNM-EDDVINQLFIASTHDYILFLSSEGNAYYLKVLEIPEASRSSRGTHVKALLQVSADE
DIQAVMP---FTD-WFVFMATARGMVKKVVLHDLRNAKTRGIRAITMKDGDKLRNAM-TSGEQELMLITRQGKGLRIDE--VRPSGRTSQGVRGINLR--
-DLSGSLVVD-QRDMLIVNATGKGKRIRFSEFNPHGRGTGGQRCM--AT--EQEVVGVISVEDQDEVVFITHQGKTVKLAIQNLRPMGAAAQGYKLVDIT
-PMVVAVDRSV-
>tr|G0GG74|G0GG74_SPITZ DNA gyrase subunit A OS=Spirochaeta thermophila (strain ATCC 700085 / DSM 6578 / Z-1203) GN=gyrA PE=3 SV=1
IEDLIQKEDMVVLVSRDGLIKRMPVSAYRRQGRGGKGLMGGKL-GDDVVSHLFVASTHDYILFLSNEGKAYYLKVHEIPEGSRVSQGKSIRSLV-QSPDE
QVSAVVSVE---EEREVFMITAKGLAKRLPVPALSNARTRGVIAIGLEKGDYLVDAF-TEGKGEVMIVTRRGHGLRCKE--FRSMGRAARGVTAVKLE--
-DVCGAVPVEE--DLLLVTSGGYGKRVGFSQFTAHGRGTKGQIVY--SR--TGELAAVLSVEAKDDVMIVTAQGNIIKLAVKDISVLGRQAAGVKVVNLE
-PYVVSVDRVA-
>tr|E1RA59|E1RA59_SPISS DNA gyrase subunit A OS=Spirochaeta smaragdinae (strain DSM 11293 / JCM 15392 / SEBR 4228) GN=gyrA PE=3 SV=1
IEDLIQKEDMVVLVSNKGFIKRVPVSSYRNQGRGGKGSSSAKL-NEDFIKHLFIASTHDYILFVTNEGKAYWMKVHEIPEGSRASRGTHIKALL-ESANE
DITTIVSLQ---EEHYLFMATARGIVKKVKTSDFRNARTRGIIAIKLDNGDTLITAV-TRGDSEIVIVSRNGNALRFHE--VRAMGRASRGVTGIRLQ--
-DLAGILRVED--KMLLLSENGLGKRVEYDHFSLHGRGTRGQIAY--SR--SGEIVGVLSVLEEDDLVCITSQGNTIKLHVSDVPVQGKTAQGVNIVTIT
-PVVVDVARVM-
>tr|V5WLJ9|V5WLJ9_9SPIO DNA gyrase subunit A OS=Salinispira pacifica GN=gyrA PE=3 SV=1
IEDLIQKEDMVVIISHKGYIKRVPVTSYRVQGRGGKGMAASKL-DDDFIENIFIASTHDYILIISSEAKAYYLKVHEIPEGSRTSKGSHIRSLL-SSANE
DVAAVVALQ---DDQFIFMATARGMVKKVSTSDFSNARARGIIAMAMKGDDKIVSAI-TSENRDIILATRTGVGLRFSE--VRPMGRTAQGVSGIRLA--
-DIAGAVEANP--HVLFITEYGNGKRMTPDDLMPHGRNTKGQIIY--SR--TGEVVGILNVLEDDEIMVVTSGGTSIKMKASTVAIQGRTAQGVRVFDIE
-PVVVGLDRVA-
>tr|R6RVA7|R6RVA7_9FIRM DNA gyrase subunit A OS=Anaerostipes sp. CAG:276 GN=gyrA PE=3 SV=1
MEDLIPRENTIITMTKLGYIKRMTVDTFKSQNRGGKGIKGMQT-DEDYIEELFMTTSHHYIMFFTNMGRVYRMKAYEIPESSRTARGTAIVNLIQLQP-E
KITAVIPIN---EDHYLFMATKSGVVKKSPIMEYAN-RKTGLLAITLKENDELIEVK-TDN-QDVFLVTKNGQCIRFHE--VRSIGRTAMGVRGINLD--
-DVIGMQLNSQGEALLFVSENGMGKRTAMTEFTPQHRGGKGIRCYKIT-E-TGDVVGVKAVDE-NEVMMITTEGVVIRMGVDGISMLGRNTSGVKLMNLD
-NIVASLAKVR-
>tr|V2XZI3|V2XZI3_9FIRM DNA gyrase subunit A OS=Catonella morbi ATCC 51271 GN=gyrA PE=3 SV=1
NDDLIPDENTVIAMTNMGYIKRMTTDNFKSQNRGGKGIKGMQT-EEDFIEDLLMTTTHHYILFFTNKGRVYRLKAYQIPEASRTARGTAMVNLLQLQP-E
QVKAVINIR---TDGYLFMATKRGIVKKTALSEYAN-RKTGLQAINLREDDDLIEVK-TNN-NDIFLVTKNGMCIRFNE--VRPTGRTSMGVIGMTID--
-TIVAMQLDTQGAKLLIVSENGLGKRTEISEFTTQHRGGKGVKCYKIV-E-TGLVIGAKSVNN-NEIMLITKAGIIIRMAVESISTLGRITSGVKLMNVD
-DVIAKIAKVR-
>tr|A5Z7E9|A5Z7E9_9FIRM DNA gyrase subunit A OS=Eubacterium ventriosum ATCC 27560 GN=gyrA PE=3 SV=1
DEDLIPEEDTVVAMTNLGYIKRMTVDNFKSQNRGGKGIKGMQT-DKDFMKDMFMVSTHDYILFLTNTGRIYKLKCYEIPEAGRTARGMAIVNLLQLQP-E
KISAMVQMK---EDKYLIMATKKGTIKKTPIMAYTN-RKSGIQAITLREDDELIDVT-SDN-DNIMLITKKGQGIKFRE--VRETGRSAMGVRGIELN--
-DVISMQLESQGECVLIVSANGMGKRTPFTDFKLQNRGGKGVKCYKIS-D-TGEVVGAKAVNG-NEIMMITNEGIVIRMFVDDISILGRVTLGVKLMNTG
KDVVASITKVK-
>tr|A0A0R1P6I4|A0A0R1P6I4_9LACO DNA topoisomerase (ATP-hydrolyzing) OS=Lactobacillus frumenti DSM 13145 GN=FD27_GL000578 PE=4 SV=1
DEDLIEEEDIIVTLTHNGYIKRLPVDEFKSQHRGGRGVKGMGV-KDDFIEHLISSDTHDLMLFFTNSGKVYSMKGYEIPEYGRSAQGIPIINLLGI-DNE
KINAVINVS--NDDKYLFFVTKQGTVKRTPVSEFQN-RSNGLKAINLHDNDELIHVA-IKD-QNMIIGTHNGYALSFDS--VRSMGRAAAGVRGIRLR--
-NVIGAAPLNDDSNVLVISELGYGKQTPASEYPIKGRGGMGVKTVNVT-K-NGPLAGLTTVQD-EDIMLVTDKGVIIRFGIESVSQTGRSALGVHLIKMD
G-TVATIAKVA-
>tr|A0A0R2GXR1|A0A0R2GXR1_9LACO DNA gyrase, A subunit OS=Lactobacillus ingluviei GN=IV41_GL000029 PE=4 SV=1
DEDLIEEEEIVVTLTHNGYIKRLPVDEFKSQHRGGRGIKGMGV-SDDFIEHLITSSTHDELLFFTNTGKVFAMKGYEVPEYGRSAQGIPVINLLGI-DHE
KISAVINVQ--HHDQDLFFATKLGVVKRTAVSEFAN-RSNGLKAINLHDHDELIAVD-IDH-QNMILGTHLGYAVSFPA--VRAMGRTAAGVRGARLR--
-GLIGAAPLNADSQVLVLSENGYGKQTPAAEYPIKGRGTMGIKTVNVT-A-NGPLVGLTTVDD-EDIMLVTDKGVIIRFGAETVSTTGRSAMGVRLIKMA
D-KVATMAIVA-
>tr|A0A0D4CMT9|A0A0D4CMT9_9LACO DNA gyrase subunit A OS=Lactobacillus mucosae LM1 GN=gyrA PE=3 SV=1
DEDLIEEEDIVVTLTHNGYIKRLPVDEFKSQNRGGRGVKGMGV-KDDFIEHLISSSTHDILLFFTNSGKVFSMKGYEVPEYGRSAQGIPIINLLGI-DHE
KITAVINVS--DTDKFLFFVTKQGTVKKTSVDDFRN-RSNGLKAIQLHDGDELIHVN-IDG-QNMILGTRLGYAVSFNA--VRSMGRSAAGVRGAKLR--
-GVIGAAPLDSDCNVFVISENGFGKQTPAAEYPIKGRGGKGIKTVNVT-A-NGPLAGLTTVKD-EDIMLVTDKGVIIRFGIETVSQTGRAAVGVHLIRMD
D-KVATMAKVA-
>tr|A0A0R2I0A1|A0A0R2I0A1_9LACO DNA gyrase, A subunit OS=Lactobacillus secaliphilus GN=IV45_GL001019 PE=4 SV=1
DEDLIEEQDIVVTLTHNGYIKRLPVDEFKTQNRGGRGVKGMGV-KDDFIEHLISSSTHDMLLFFTNSGKVFSMKGYEIPEYGRSAQGIPVINLLSL-DHE
KISAVINVS--DEDKDLFFATKQGIVKRTPVAEFQN-RSNGLKAINLHENDELIAVE-IDH-QNLILGTHQGYSVSFNS--VRSMGRAAAGVRGARLR--
-NLIGAGKLNPDDNVLVISANGYGKQTPAAEYPIKGRGGKGIKTVNVT-S-NGPLVGLTTVKD-EDIMLVTTKGVIIRFGVETVSTTGRSTIGVHLIKLT
G-QVATMAKVA-
>tr|B5IAL1|B5IAL1_ACIB4 DNA gyrase subunit A OS=Aciduliprofundum boonei (strain DSM 19572 / T469) GN=gyrA PE=3 SV=1
IEDLIPNEEAVIILTEKGYIRRLKVDEYRAQGRGGKGVMI-NY-EGDLPRDITTANLHDYLMFFTKNGRVYWLKAYEVPEGTRRSRGRAIINII-PLGSD
VI-RMLSLN--DFSGYLFFITRNGIVKRTSLEEFSNPRSTGIRAIIFDEDDELVDVK-THGGEDIFLFTKYGKAIRFSE--VRVMGRTARGVIGIKLQ--
-DVISSAVE--GPYVFAVLSSGYGKRTPIGEYRRIRRGGMGVRNI--R----ANVVKSLLTTENDEALLLTKNGMSIRIKLRDVSVMGRNARGVKLIKLD
-GEVVNVAKL--
>tr|A0A0G0GAF5|A0A0G0GAF5_9BACT DNA gyrase subunit A OS=Parcubacteria (Magasanikbacteria) bacterium GW2011_GWC2_37_14 GN=gyrA PE=3 SV=1
VEDLVPNESTIIMTTRDGYIKRLPPDTFKTQGRGG-G--IVT--ED-IVDQLISTNTHDNILFFTTRGRVFQLRAYDIPQT-RTAKGQAIVNFL-QAN-E
K--AILSVT---KYKFLVMVTNKGTTKKTALTDFAN-R-SGLIALKLK--DMLEW---SD---EIMIVTAGGQAI------IRPMGRTASGVRGMRLKS-
-NIVGMDVISPVLELLVVSENGLGKRTLI-EYK-QGRGGSGIKTM---TPKTGKI-SVDVIN-EKDLMAISVNGQVIRIEL-TVST-GR---GVRIMRFK
E-KVASATLL--
>tr|A0A0G2BB64|A0A0G2BB64_9BACT DNA gyrase subunit A OS=Parcubacteria (Magasanikbacteria) bacterium GW2011_GWA2_56_11 GN=gyrA PE=3 SV=1
IEDLVPNEPTIIMATKDGYIKRMPVDTFRTQGRGG-G--ILT--ED-VIEHLISTNTHDNMLFFTNRGRVFQLRAYDIPVS-RTAKGQALVNFL-QAN-E
Q--AILSMA--SQYKYLVMVTNKGTIKKTELDDFKN-R-SGLIALKLR--DMLEW---SD---DIMIVTALGQAI------VRDMGRTASGVRGVRLKS-
-NVIGMDVVSPVLELLVVAENGLGKRTDV-EYK-QGRSGSGIKTM---TDKTGPI-NARVIN-KQDLLLISVKGQVVRTPL-SVPS-GR---GVRIMRFK
D-RVANITLLE-
>tr|K2DMH0|K2DMH0_9BACT DNA gyrase subunit A OS=uncultured bacterium (gcode 4) GN=gyrA PE=3 SV=1
MEDLVPNEPTLIISTRDGYIKRLPPDTFKQQSRGG-G--ILT--ED-VVDKIISTNTHDNILFFTTRGRVFQLSAYDIPQT-RTAKGQALQNFL-QAN-E
K--VFLSMD--GSYESLVMVTSKGNIKKTKLEDFKN-R-SGLIALKLK--DMLEW---TN---DIMITTSMGQSI------VRAMGRTASGVRAIKLKS-
-TVVGMSILDNVLELLVVSENGMGKKTKI-EYK-QGRGGSGIKTM---TSKTGKI-SSQVVN-EKDIMIISVKGQVIRTSL-SIST-GR---GVRIMRFK
E-KVAAIAFV--
>tr|A0A0G0VGK4|A0A0G0VGK4_9BACT DNA gyrase subunit A OS=Parcubacteria (Uhrbacteria) bacterium GW2011_GWC1_41_20 GN=gyrA PE=3 SV=1
MEDVIPDEQTIVMFTKDGYIKRVLPDTFKLQSRGG-G--LLS--ED-MVESIFTTTTHKDIMFFTSSGRVFKLKVYEIPES-RTSKGQAIVNFL-QAG-E
T--ATMEP---ESAKYIVMVTSKGTIKKTDMKDFEN-R-SGLIAIKLK--DTLEW---SD---DIILTTSNGMAI------LRSMGRVASGVRGLKLKG-
-EVVGMEIIDDDCQLMVIMQNGYGKRTAL-EYK-QGRGGMGIRTA---TSKTGNV-SARLAF-PRDLLVISEDGQVIRMAI-SISS-SR---GVRVMRFK
S-KVISVAVLE-
>tr|A0A0G0ZWB4|A0A0G0ZWB4_9BACT DNA gyrase subunit A OS=Parcubacteria (Magasanikbacteria) bacterium GW2011_GWC2_42_27 GN=gyrA PE=3 SV=1
MEDLVANEATIIMATRDGYIKRMPADTFKTQARGG-G--ILT--ED-VIEHLIATNTHDNLLFFTTRGRVFQLRAYDVPQT-RTSKGQALVNFL-QAN-E
N--VILSMD--LKYKNLVMVTNKGTIKKSALEDFKK-R-SGLIALKLA--DMLEW---SD---DIIIATSQGQAI------LRPMGRTAKGVRGMKLKS-
-NVVGMDVVSPVLEMLVISENGLGKKTEL-EYK-QGRGGSGIKTM---TAKTGPI-SMRVIN-NQDTLLISRKGQVVRVPL-SVST-GR---GVRIMRFK
E-TVVGMALLL-
>tr|D6U6S9|D6U6S9_9CHLR DNA topoisomerase (ATP-hydrolyzing) OS=Ktedonobacter racemifer DSM 44963 GN=Krac_1306 PE=4 SV=1
VASLHEREPLTVAFAFPGTLKALAPDTFKPKQKNGVL-------DE-QLRQVVATTTRDYLLCMSSTGRVFQVGSHRLPLT-RSAKGEVIRDLLE--G-E
E--AVVPID---EDRYMVTFSRLGKVKKSPLSEYKI---DGAQDMKL--GDSVVT---R---GEYFVTTDYAQTL------L---GRVGQGVAAIALA--
-GVVVSASY--LNSLLVVTEQGTLKKVPVS-----GRATGGVVTT--GK---DRL-SMLVNE-QDHLLLGWTGRNGLVLPV-EVKA-PRVKQGVE----V
N-RIL-VVK---
>tr|D1C5K4|D1C5K4_SPHTD DNA topoisomerase (ATP-hydrolyzing) OS=Sphaerobacter thermophilus (strain DSM 20745 / S 6022) GN=Sthe_0081 PE=4 SV=1
VASLIEERPILIVASQSGRVKALPENAFKRARAG----------GE-GLAAIVPASTLDYLLVLTRGGRVYLSRGHEVPAT-RASSGEPAQKVFG--D-E
A--TILPVN---EDRYVVWFTANGKVKKTSLAEYRS---AGLNDLRL--DDRVVA---E---GEYLVIASNGQAL------V---GRDGQGVNAIALK--
-GVVTALAI--DGDVLVVTAQGMGKRTALK-----RRATAGVAAI--AG---DRA-AALVTP-DDDVVLGAAGGQA-QVTV-DLRR-GRATKGSRLLEVA
N-HVA-IAR---
>tr|I4ELX3|I4ELX3_9CHLR DNA topoisomerase (ATP-hydrolyzing) OS=Nitrolancea hollandica Lb GN=NITHO_5400005 PE=4 SV=1
VASLVEEQPVLILVSTSGRVKAIPANSIRRQRPSTND--TSA--AD-GAAIIVPASTLDYLLVLTSSGRVYLSRGHEVPLT-RASAGDPVQKVFG--D-E
A--AILPVA---DGRYVVWFSANGKVKKTALSEYRS---AGLNDFKL--GDSVTA---D---GEFLVIASDGHAL------V---GRDGQGVNAMTLK--
-GVVAGLAL--AGDLFIVSADGLGKRTALA-----HRATSGIAAI--AD---DRA-ALLAAS-GDGALVASAGGRL-RLAL-SLRR-GRATKGSPLMVLA
K-RIS-VGR---
>tr|K0ELP1|K0ELP1_9NOCA DNA gyrase subunit A OS=Nocardia brasiliensis ATCC 700358 GN=gyrA PE=3 SV=1
DEDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVQGA-GKQDDLVKHFFISSTHDWLLFFTNKGRVYRAKAYELPEANRTARGQHVANLLAFQPDE
KIAQIIQIK---AP-YLVLATKNGLVKKSKLSDFDS-RSGGIVAVNLRD-DELVGAV--SADDDLLLVSALGQSIRFSE--LRPMGRATSGVQGMRFN-S
-DLLSLNVVRPDTYLLVATAGGYAKRTAIEEYTAQGRGGKGVLTVQYD-PKRGTLVGALIVEE-DELYAITSGGGVIRTVAKQVRK-GRQTKGVRLMNLG
-GTLLAIARNA-
>tr|K2BT05|K2BT05_9BACT DNA gyrase subunit A OS=uncultured bacterium (gcode 4) GN=gyrA PE=3 SV=1
EEDLIPNEPTVITLTNTGYIKRQSLNSFRVQQRGG-G--KMT--ED-GILSIRYAETHDNILFFTNRGKVYQLRAYEISES-RTSKGTAVVNLI-NEG-E
R--SFINYK--DNHGYVFLTTKNGTVKKTSLKEFEN-R-NGIIAIKLE--DELVW---TE---DIILTTREGKAI------VRPLGRSTMGVRGIKLGS-
-GVISQDVIDK-PDVLAIMENGLGKKTSA-SFR-QSRGGVGVKIA---NPKTGKA-FAAVIS-CKEIIITSNRGQVVKIPI-QIPR-SR---GIILMRFS
S-KITSATCVE-
>tr|A0A0G0HBR2|A0A0G0HBR2_9BACT DNA topoisomerase (ATP-hydrolyzing) (Fragment) OS=Microgenomates (Levybacteria) bacterium GW2011_GWB1_37_8 GN=US59_C0050G0001 P
EEDLIPNEPTVITITDTGYIKRQSLNSFRVQHRGG-G--KMT--ED-GILNIRYAQTHDNILFFTNKGKVYQLRAFEIAEQ-RTSKGTAIVNLI-NEE-E
K--SFINYKGIETFKYVFLSTKNGTVKKTALTEFEN-R-NGILAIKLD--DELVW---T---NEVILTSHNGKAI------VRPLGRSTRGVRGIRLQ--
TDVISMDVIKKKTDLITIMENGLGKKTPV-QFR-QSRGGQGVKVA---TPKTGKA-FAQVIP-YKTLIMTSRRGQVVKLEL-SIPR-SR---GVKLMRFS
P-RVTSATCVE-
>tr|A0A0G0V243|A0A0G0V243_9BACT DNA gyrase subunit A OS=Microgenomates (Levybacteria) bacterium GW2011_GWA2_41_15 GN=gyrA PE=3 SV=1
DEDLIPNEPTVLTLTTTGYIKRQSLGSFRTQLRGG-G--KMT--ED-TIMNIRYAQTHDNILFFTNRGKVYQLKVYEIGES-RTSKGSAVVNLI-NEG-E
K--SFVTYG--DKFSHVFLTTRKGVVKKTKLSEFEN-R-NGILSIKLD--DELVW---TD---NALIFTRNGKSI------VRPMGRNTRGVRGIRLIG-
-EVVGMDIITK-PDLLTIMDKGLGKKTSA-QFN-QSRGGQGVKVA---SPKTGKA-ASQIIP-CNEVIITSEKGLVVKLSL-SIPR-SR---GVILMRFS
P-SVASITCIE-
>tr|A0A0G0GV85|A0A0G0GV85_9BACT DNA gyrase subunit A OS=Microgenomates bacterium GW2011_GWA2_37_6 GN=gyrA PE=3 SV=1
EEDLIPNEPTVITLTTTGYIKRQSLTSFRTQHRGG-G--KMT--ED-GIMHIRYTMTHDNILFFTNKGKVYQLKAYEIDES-RTSKGTAVVNLI-NED-E
K--SFIQYT--DEFKYVFLTTRNGTVKKTVYSEFEN-R-SGIVAIKLD--DELVW---TD---DIFVFTRNGKCI------VRPLGRATRGVRGIKLSG-
-DVVGMDVVVR-PQFLTIMENGYGKKTVV-EFN-QSRGGMGVKIA---TQKTGKA-SSQVIP-CKEVIITSRKGQVVKIDI-AIPK-SR---GVILMRFS
P-KVAAITCVE-
>tr|A0A0G0TQ80|A0A0G0TQ80_9BACT DNA gyrase subunit A OS=Microgenomates (Levybacteria) bacterium GW2011_GWA2_40_8 GN=gyrA PE=3 SV=1
EEDLIPNEPTVLTLTATGYIKRQSLNSFRTQHRGG-G--RMT--ED-TILHIRYAQTHDSIIFFTNRGKAYQLKVYEISES-RTSKGSAIVNLI-NEG-E
K--SFITYS--DKFNYVFLTTRGGTVKKSKLSEFEN-R-SGILAIKLE--DELVW---TD---NVLLFTKNGKSI------VRPMGRNTQGVRGIRLVG-
-EVVGMDIIAK-PDLFTITEKGLGKRTSV-QFH-QSRGGQGVKVA---TSKTGKS-ASQIIP-FNEVIITSKRGLVVKLLI-QIPK-SR---GVILMRFS
P-TVASITCIE-
>tr|A0A0G1UCN5|A0A0G1UCN5_9BACT DNA gyrase subunit A OS=Microgenomates bacterium GW2011_GWA1_48_10 GN=gyrA PE=3 SV=1
EEDLIANESMIVTVTKTGYIKRLSPASYRAQARGG-G--TMT--ED-EIDHLTTANTHDNILFFTNSGKVYQTRVFELPES-RQAKGQAVVNLI-NEG-E
I--SILAYD--KFAKYIFLTTKQGTVKKSPVTDFAN-R-NGLTAIKLE--DELVW---TD---DILLVTHEGKSI------VKPQGRDTIGVRGIKLGK-
-NVVGMESVPSATDLLVVSEKGVGKRTAV-QFP-QGRGGQGVKAM---TTKTGNV-TARLVD-IDQLILTSAKGIVIKLPL-SIPK-SR---GVILMRFS
T-RLAAVTTLE-
>tr|B3QRZ3|B3QRZ3_CHLT3 DNA gyrase subunit A OS=Chloroherpeton thalassium (strain ATCC 35110 / GB-78) GN=gyrA PE=3 SV=1
VEDMIAEEDVVITITHQGYIKRFPVSGYRRQGRGGRGISGVSA-EDDFIEHMFIASTHHYILFFTSHGKCYWLKVHEIPEAGRTARGRSITNLIEFAT-E
KIKASINVK----TQFIVMATKNGTIKKTPLSEYSN-RRSGIIAINITDNDELVGAS-TDG-HQIVLAKNTGYAVRFPE--VRPMGRNSIGVKGASIS--
EAIISMV-STPDATLLAITDNGYGKRSAIEDYRMTKRGANGVITLKAN-E-VGKLVDMLEVNG-EDIIIITNKGIVNRQHIADIRVMGRNTSGVRLIRLD
-DFVSAVARVP-
>tr|I7A2W9|I7A2W9_MELRP DNA gyrase subunit A OS=Melioribacter roseus (strain JCM 17771 / P3M-2) GN=gyrA PE=3 SV=1
LEDIIAEEDVVVTISHRGFIKRFPVSGYRRQSRGGKGVTGAGT-DEDFIEHMFVASTHHYIMFFTDKGKCYWLKVHEIPEGGRTAKGRSILNLIEKSK-E
KIAAFVAVK----DKYVVMVTEKGTIKKTVLSAYSN-RRGGINAINLADGDNLVEAK-SDG-NDIIIGTRNGMAIRFNE--VRDMGRTATGVRGINLA--
DKVIGMIVVRNS-TLLVVTNKGYGKRSELDDYRLTRRGGKGIITIKTS-E-NGKMIAMKEVNT-DELVIITTKGMVIRQAVKDIRIMGRNTQGVRLIKLN
G-EIADIARVA-
>tr|Q3B6P3|Q3B6P3_CHLL7 DNA gyrase subunit A OS=Chlorobium luteolum (strain DSM 273 / 2530) GN=gyrA PE=3 SV=1
IEDMIAQEDVVITVTHDGFIKRFPVSGYRRQARGGKGVTGAQA-HDDFIEHMFVASTHNYILFFTNTGRCYWLKVYEIPEAGRAARGRALANIMELHP-E
KIKAYINIR----PGYIIMATADGIVKKTALEEFSR-RRNGIAAITIDEGDALLDAR-TDG-HQVILAKSSGLVVRFPE--VRPMGRTAMGVKGITLD--
EKCIAMV-TTKDTALLAVTDNGFGKRSRVEDYRLTKRGARGVITLKAH-E-IGSLVGLLDVND-DDLILITTHGIVNRQHVSDIRITGRNTSGVKLIRLM
-GTISALARVP-
>tr|A0A081SFH7|A0A081SFH7_9CHLB DNA gyrase subunit A OS=Chlorobium sp. GBChlB GN=gyrA PE=3 SV=1
LESMIKEEDVVITITHEGFIKRIRVNDYRRQGRGGKGVAGAAT-DEDFVEHMFIASTHHYILFFTTFGKCYWLKVHEIPEAGRAARGRSLNNLMELES-E
KIRAYINVK----SLYVVMATKNGMIKKTALSEYSN-RKTGIIAVNIEKGDELIEAK-TDG-HQIVLAKNSGYAVRFME--VRPMGRSATGVKGAEVE--
EEVVSMV-TTRDITLLTITDSGYGKRSDLEEYRMTKRGAAGVITLKAN-E-VGNLVAMIEVAT-DDLILITKNGIVNRQHVSDIRVMGRNTSGVRLIRLQ
-GAVSAVARVP-
>tr|B3QRK9|B3QRK9_CHLP8 DNA gyrase subunit A OS=Chlorobaculum parvum (strain NCIB 8327) GN=gyrA PE=3 SV=1
IEDMIAQEDVVITITHDGFIKRFPVSGYRRQHRGGRGVAGAQA-NEDFIEHMFIASTHNYILFFTTAGRCYWLKVYEIPEAGRSARGRSLANIMELPP-E
KIRTYINIR----PHFIIMATANGIVKKTDLKQYSN-RRTGINAITIEEGDELIEAR-TDG-HQVILAKSSGYAVRFPE--VRSMGRTAMGVKGITLD--
ERCISMV-TTKDTSLLAVTDNGYGKRSKVEDYRMTKRGARGVITIKAH-E-IGNLVGLLDVNE-DDLIIITTNGIVIRQHVSDIRVLGRNTSGVRLIRLD
-GRISATARVP-
>tr|B4S3A3|B4S3A3_PROA2 DNA gyrase subunit A OS=Prosthecochloris aestuarii (strain DSM 271 / SK 413) GN=gyrA PE=3 SV=1
IEDMIAQEDVVITVTHDGFIKRFPVSGYRRQARGGKGVTGAQA-LDDFVEHMFIASTHNYILFFTSMGRCHWLKVYEIPEAGRTARGRSLANIMELQK-E
TIRAYINVK----PLFIVMATARGLIKKTEIEAFSR-RRNGIAAISIEDGDELIEAR-TDG-HDIIMAKNSGYAVRFAE--VRAMGRTAMGVKGITLD--
EYCISMV-TSKDTSLLAVTDNGFGKRSLVDDYRLTRRGARGVITLKAH-E-VGNLVGLLDVNG-DDLIIITANGIVNRQHVSNIRLTGRNTSGVRLIRLM
-GKISATARVP-
>tr|A1BJS0|A1BJS0_CHLPD DNA gyrase subunit A OS=Chlorobium phaeobacteroides (strain DSM 266) GN=gyrA PE=3 SV=1
IEDMIAQEDVVITITHDGFIKRFPVSGYRRQARGGKGVAGAQA-HDDFVEHMFIASTHNYILFFTTRGRCYWLKVYEIPEAGRTARGRSLANIMELQP-E
KIRAYINIR----PGFIVMATGNGTVKKTGLDEFSR-RRNGIAAITIEENDELIDAR-TDG-HQIILAKSSGYVVRFPE--IRSMGRTAMGVRGITLD--
EKCISMV-TTKDTTLLAVTDNGFGKRSRVEDYRLTKRGARGVITLKAH-E-TGAMVGLLDVNE-DDLIIITNNGIVNRQHVSDIRLTGRNTSGVRLIRLM
-GIISALARVP-
>tr|B3EE75|B3EE75_CHLL2 DNA gyrase subunit A OS=Chlorobium limicola (strain DSM 245 / NBRC 103803) GN=gyrA PE=3 SV=1
IEDMIAQEDVVITITHDGFIKRFPVSGYRRQARGGKGVTGAQA-HDDFIEHMFIASTHNYILFFTNTGRCYWLKVYEIPEAGRAARGRSLANIMELRP-E
QIKAYINIR----PGYIVMATTNGIVKKTPLDDFSN-RRTGIAAITIEEGDELLDAR-TDG-HQIILAKSSAYAVRFPE--IRSMGRTAMGVKGITLD--
EKCISMV-TTKDTALLAVTDNGFGKRSRVEDYRLTRRGARGVITLKAH-E-IGALVGLIDVND-DDLIIITTNGIVNRQHVSDVRMTGRNTSGVRLIRLM
-GKISALARVP-
>tr|I0AFG3|I0AFG3_IGNAJ DNA gyrase subunit A OS=Ignavibacterium album (strain DSM 19864 / JCM 16511 / NBRC 101810 / Mat9-16) GN=gyrA PE=3 SV=1
LEDIIAEEDVVVTISHQGFIKRFPVSGYRKQARGGKGVTGVGT-EDDFIEHMFVASTHQYILFFTDRGRCYWLKVHEIPEGGRTARGRSIVNLLEKDK-E
NITAFVAVK----DQYLIMVTEQGTVKKTVLSAYGN-RKGGINAINLVPGDKLIEVK-TDG-NDIVIGTRNGFAIRFHE--VRDMGRTATGVRGIKLV--
DKVVGLLVIRHQTSVLVVTEKGYGKRSDINDYRITKRGGKGVITVKTT-D-VGKMIAMMEVVK-DELVIISTQGMVIRQSVKDIRVMGRNTQGVRVIRLN
G-SIADIARVI-
>tr|B3EK37|B3EK37_CHLPB DNA gyrase subunit A OS=Chlorobium phaeobacteroides (strain BS1) GN=gyrA PE=3 SV=1
IEDMIAQEDVVITITHETFIKRFPVSGYRRQARGGKGVTGAQA-HEDFVEHMFVASTHNYILFFTNKGRCHWLKVYEIPEAGRAARGRSLANIMELQP-E
KIKAYINVK----PLFIIMATAKGSIKKTEIEAFSR-RRNGIAAITIEDGDELIDAR-TDG-HDIILAKNTGYAVRFAE--VRPMGRTAMGVKGISLD--
ETCISMV-TSKDTSLLAVTDNGFGKRSKVEDYRLTRRGAKGVITLKAH-E-VGHLVGLLDVNS-DDLIIITSNGIVNRQHVSNIRLTGRNTSGVRIVRLM
-GTISATARVP-
>tr|A0A0A7LIE3|A0A0A7LIE3_9EURY DNA gyrase subunit A OS=Candidatus Methanoplasma termitum GN=gyrA PE=3 SV=1
EEDLIPMEDVVITISADNYIKRIPLNTYRQQARGGVGLIGMQT-EEDYVSSMFVASSHDYLMFITNHGRLHWLKGYRVPEGSRQSKGKPIINMISDEEGE
MVVSTICVH---ENEYLAFCTKNGLLKKTSLSAYKNVRARGIKAIKFDEGDELIETS-TEENDQIIIATKNGQAVRFNE--VRSTGRDTMGVKGVTLN--
-DVISMAVVRPEDKLLTVTENGYGKISDVADYRQTNRGAKGVITI--DR--NGKVVSVRKVSAGDQLMVTSMSGKMIRMSVDEIRETGRNAKGVRIMDMR
-GKVTAVQPII-
>tr|C1A5L6|C1A5L6_GEMAT DNA gyrase subunit A OS=Gemmatimonas aurantiaca (strain T-27 / DSM 14586 / JCM 11422 / NBRC 100505) GN=gyrA PE=3 SV=1
IEDLIAEEEMVVTITHGGYIKRTPLSLYNRQGRGGRGKASADL-EHDFIERFYVASTHTYMLIFTDDGRCFWLKVHELPQAGRNTRGKPIVNLI-NTPDT
RIRAIVVTK---DTEFLLFCTRNGTVKKTALSQYSNPRANGIKAIKIEQDDELMDVQ-TSGNNDVVLATRHGLSVRFHE--VREMGRDTTGVKGIELR--
-DLVGMVVIKR-ATLLVVTERGLGKCSEVSEYRVQKRGGKGILTL--TK--TGDVIALMEVVPEDELMLMTRQGIAIRSKVSEIRVTGRAAQGVKLVALD
-LGVSAVARVI-
>tr|W0RKH2|W0RKH2_9BACT DNA gyrase subunit A OS=Gemmatirosa kalamazoonesis GN=gyrA PE=3 SV=1
IEDLIAEEDMVVTISHSGYIKRTPVTTYRRQRRGGRGLSGQDL-DTDFIERLFIASTHDYIMIFTDDGRCFWLKVHEIPQAGRATRGKPIVNLI-NTPDT
GIRSMVPVR---EDQYLLFCTKQGTVKKTCLSEYGNVRANGVKAIKIERGDELIDVQ-TSGTNDIVLATKHGLSIRFHE--VRDMGRDTTGVKGVELR--
-DVISMVVIKR-ATLLVVTEKGMGKVTDIDEYRVQKRGGKGIITV--TK--TGNVVSLMEVLPEDEIMLITKQGIIIRSAVNEVRNTGRNAQGVRLVNLD
-NIVCSVARVV-
>tr|F5LHF6|F5LHF6_9BACL DNA gyrase subunit A OS=Paenibacillus sp. HGF7 GN=gyrA PE=3 SV=1
DEDLIPQEDVVITITHTGYIKRLPVNTYRSQKRGGRGIVGMDT-TDDFVNHLFVTNTHHYLLFFTDRGKVYKLKAYEIPDLSRTARGTPIINLIQIEQ-E
TVSAVIPVQ---ADNYLFFATKRGIVKKTPLDDYIN-RKGGLIAINLRDDDSLIGVK-TDG-RHIIMGTRDGMSIRFPE--VRSMGRSATGVKGIQIG--
-EVIDMDVVDEDASVLIVTSKGFGKRTPIAEYRVQSRGGKGIKTLNVT-T-NGAVVGLKVVNE-EDLMIITASGTLIRTSISGISEMGRNTQGVRLINIR
D-EVATVTHVA-
>tr|W2EE58|W2EE58_9BACL DNA gyrase subunit A OS=Paenibacillus larvae subsp. larvae DSM 25719 GN=gyrA PE=3 SV=1
DEDLIPREEVVITITHSGYVKRLPVSTYRSQRRGGRGVVGMDT-NNDFVEHLFVTNSHHYLMFFTDKGKVYRLKAYEIPELGRTARGTPIINLIQIEQ-E
TVNAVIPIE---SGHFLFFATQQGIVKKTPLKDYNN-RKGGLIAINLREDDRLIGVK-TDG-CNIIMGTRQGMSIHFPE--VRSMGRAATGVKGIHIS--
-DVIDMDIVDENNTVLIVTSKGFGKRTPMSEYRIQTRGGKGIKTLNVT-S-NGPVVGLKVVED-EDLMIITASGTVIRTSMSGISIMGRNTQGVRLINTR
D-EVATVTRVE-
>tr|A0A0N8PUC7|A0A0N8PUC7_9BACL DNA gyrase subunit A OS=Paenibacillus sp. A3 GN=QJ48_19480 PE=4 SV=1
DEDLIPQTDVVITISHTGYIKRLPVSTYRSQRRGGKGVIGMDT-DDDFVEHLFVTNSHHYLMFFTDKGKVYRLKAYEIPDLSRTARGTPIINLIQIEQ-E
TINAVIPVE---SDKYLFFATKNGLVKKTPLDDYSN-RKGGLIAVTLREDDDLIGVR-TDG-QSIIMGTKEGMSIHFPE--VRAMGRAATGVKGIQLD--
-GVIDMDVVHEDNSVLIVTSKGFGKRTPVSEYRLQSRGGKGIKTLNVT-P-NGPVVGLKIVQE-EDLMIITASGTVIRTSMSGISLMGRNTQGVKLINIR
E-EVSTLARVD-
>tr|H2CFZ0|H2CFZ0_9LEPT DNA gyrase subunit A OS=Leptonema illini DSM 21528 GN=gyrA PE=3 SV=1
ITDLIHDEDVIITFSEDGFIKRTPIDTFKRQKRGGKGVKGASM-KEDVIKLISHASTHDNLLLFSNKGKIFAMKVHEIPEAGKDARGKSIKAVLNLAADE
KITAMTS---FAE-RAIVMISRDGILKKSNLDLFANARKGGIIAISLRKDDELINVC-VNPKDDILIATRNGLALRTNL--MKSQGRQASGIIGIRLE--
-DVIGMDVVVE-SDLFVITELGYGKRMAFKNFPVKGRGTKGMMYV--GR--IGPAVAIQTVQKDDDVIIICQSGQIIRVSVDEISTQGRSTQGVRIVTLH
-NSIQDVAILK-
>tr|A0A084JW58|A0A084JW58_9FLAO DNA gyrase subunit A OS=Nonlabens ulvanivorans GN=gyrA PE=3 SV=1
IEDMIADEQVVITISHAGYIKRTPITEYKTQNRGGVGQKASTT-DEDFLEDIFVGTNHQYMLFFTEKGKCFWMRVYEIPEGSRTSKGRAIQNLINIEQDD
NVKAVICTQK--NSHYVIMCTKKGVVKKTSLEQYSR-RTNGINAITIREGDTLLEAKLTTGDSHVMLGLKSGKAIRFD---TRAMGRNASGVRGIRLAD-
-DVIGMVAVNDDSNILVVSEKGYGKRSSLD-YRETNRGGKGVKTISVTE-KTGGLVALKNVT-DDGLMIINKSGVAIRIDVKNLRVMGRATQGVRLINLK
-NSIAAVAKVA-
>tr|A0A0L6JV57|A0A0L6JV57_9FIRM DNA gyrase subunit A OS=Pseudobacteroides cellulosolvens ATCC 35603 = DSM 2933 GN=gyrA PE=3 SV=1
IEDMINEEENVITLTHFGYIKRQPTDSYKSQRRGGKGIIGLST-EEDFVENLFTTSTHDFILFFTNKGRVFRKKAYEIPEG-RQAKGTAIVNLLQLNP-E
RVATVIPIS---EGSYLVMATKNGLVKKTDLMEYDS-RKGGLAAVALKDNDELIDVK-TDG-QDIMLATVKGMSIRFNE--VRSVGRVSQGVKGIDLE--
-DVIGMEVCSE-LCLLVVTENGFGKRSELDEYKVQSRAGKGILTYRVT-S-TGNLAGVKLVDN-DDIMLISSDGTIIRMNVSEISILGRATQGVTLMRMN
GD-VVCVARIV-
>tr|S0FXE9|S0FXE9_9FIRM DNA gyrase subunit A OS=[Clostridium] termitidis CT1112 GN=gyrA PE=3 SV=1
IEDLIQEEESVITMTHFGYVKRLPADTYKSQRRGGKGIIGLST-EEDFVKNLFVTSTHNFIMFFTNKGRVYRLKAYEIPEG-RQAKGTAIVNLLQLNGDE
KVTTVIPIQ---EGLYLVMATRNGLVKKTDLMEYDN-RKGGLAAVTLRENDELIDVK-TDG-QDIMLSTVNGMAIRFKE--ARPIGRVSQGVKGIELD--
-DVIGMEVVT--TTLLVVTENGFGKRTELEEYKVQTRGGKGILTYRIT-E-TGKSIGMMLVSE-DDIILISSDGSIIRMKVNEISILGRATQGVTLMRMS
EGNVVSMARMI-
>tr|L7VSI3|L7VSI3_CLOSH DNA gyrase subunit A OS=Clostridium stercorarium subsp. stercorarium (strain ATCC 35414 / DSM 8532 / NCIMB 11754) GN=gyrA2 PE=3
IEDLIDNTDIVITLTHYGYIKRTSVDEYKIQKRGGRGVMGLTT-EDDFVTSIYTATTHHLLLFFTNRGKVYKLRAWDIPEG-RHAKGTAIVNLLELEPGE
KVSAVIPIT---KDMFLFMATRQGMVKKTPLEQFEN-RKGGLIAVTLKEGDELIEVR-TDG-DDVILITKNGMSIRFPE--VRPMGRNSQGVIGIKLS--
-DVISMLRYT--TTLLVVTENGFGKRTDIEEYKVQNRGGKGILTYKVT-E-TGFVVGAKLVDQ-DDILLVNTDGNIIRLHVGEISILSRVTQGVTLMKTA
EGKVVSVARIT-
>tr|G8LUJ5|G8LUJ5_CLOCD DNA gyrase subunit A OS=Clostridium clariflavum (strain DSM 19732 / NBRC 101661 / EBR45) GN=gyrA PE=3 SV=1
VEDLIEEENCVITLTHFGYVKRIPTDTYKSQRRGGKGIIGLST-EEDFVENLFTTSTHDYILFFTSKGKVYRLKAYEIPEG-RHAKGTAIVNLLQLEP-E
KITTVIPLK---EGLYLVLATKNGIVKKTDLMEYDH-RKGGLTAVTLKENDELIDVK-TDG-KDIILVTRNGMSIRFNE--VRPLGRVSMGVRGIKLD--
-DVVGMGVYIE-TSLLVVTERGFGKRTELEEYKVQTRGGKGILTYRVT-E-TGKIAGMKLVNK-DDVMLISSDGSIIRINVSDISILGRATQGVTLMRLD
SV-LVGVARIA-
>tr|R6NPN1|R6NPN1_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:413 GN=gyrA PE=3 SV=1
IEDLIPEEQCVFTLTDMGYIKRIPMDEYKQQGRGGKGVKGLTR-EEDVVKTMFTCSTHDHIMFFTTMGRAYRLKGYEIPES-RQSKGMNVVNLLPLMPGE
KVSSMIRVPE--GDYYLCMVTRNGVIKRTELDAYKNIRKNGVIAINLDEGDELAWVKLTDGSAKLVLATKKGMCIAFD---ARSIGRTARGVKALNLK--
-TVVGMDIL--GGMVLTVSETGYGRLSEVTDYKLQNRGGMGTKNYHT-A-KYGDVAAIEVVD-ADDLMLISSDGIIIRIALNNIRI-SKPAKGVRVMKVS
-GRLITAVSVP-
>tr|E6JAY4|E6JAY4_9ACTN DNA gyrase subunit A OS=Dietzia cinnamea P4 GN=gyrA PE=3 SV=1
DEDLIAREDVVVTITETGYAKRTRTDLYRAQKRGGKGVRGA-EKQDDIVRHFFVSSTHDWLLFFTTKGRVYRIKAYELPEANRTARGQHVANLLAFQPEE
RIAGVIRIK---AP-YLVLATRNGLVKKSRLEDYDS-RSGGLIAVNLRD-DELVGAA--GPDDDLLLVSEKGQSIRFHD--LRPMGRATSGVMGMRFN-G
-DLLSMSVVRAKYFLLVATERGYSKRTALSEYTAQGRGGKGVLTLMFD-PKRGKLVGATIVEQ-DELYAITSSGGVIRTFAKQVRK-GRQTKGVRLMNLA
-GSLLAIARNA-
>tr|I6ZLD9|I6ZLD9_STRIN DNA gyrase subunit A OS=Streptococcus iniae GN=gyrA PE=3 SV=1
DEDLIEEEDVLITLSNKGYIKRLAQDEFRAQKRGGRGVQGTGV-DDDFVKELVSTSTHDTLLFFTNLGRVYCLKAYEIPEYGRTAKGLPIVNLLKL-DGE
TIQTIINAR--V-DKYFFFTTRQGIVKRTGASEFNN-RQNGLRALNLKEGDQLINVL-TDG-EDIIIGTKSGYSVRLQE--IRNMGRSATGVRGVKLR--
-DVVGASTITDHQEVLIITENGYGKRTLASEYPTKGRGGKGIKTANIT-A-NGELAGLTTVND-EDIMVITNKGVIIRTSLANVSQTGRATLGVKVMRLD
E-KIVTFALVN-
>tr|G5KBS8|G5KBS8_9STRE DNA gyrase subunit A OS=Streptococcus pseudoporcinus LQ 940-04 GN=gyrA PE=3 SV=1
DEDLIEVEDVLITLSNKGYIKRLAQDEFRAQKRGGRGVQGTGV-DDDFVKELVSTSTHDTLLFFTNKGRVYRLKAYEIPEYGRTAKGLPIVNLLKL-DEE
TIQTIINAR--D-NKFFFFTTRQGLVKRTNASEFGN-RQNGLRALNLKDGDELINVL-TDG-EDIIIGTKSGYSVRFEE--IRNMGRSATGVRGVKLR--
-GVIGASRISDSQEVLVITEKGYGKRTRATEYPTKGRGGKGIKTANIT-A-NGQLAGLVTVTH-EDIMIITNKGVIIRTSIADVSQTGRSTMGVKVMRLD
D-KIVTFALVD-
>tr|B9DS54|B9DS54_STRU0 DNA gyrase subunit A OS=Streptococcus uberis (strain ATCC BAA-854 / 0140J) GN=gyrA PE=3 SV=1
DEDLIEEEDVLITFSNKGYIKRLAQDEFRAQKRGGRGVQGTGV-DDDFVKELVSTSTHDTLLFFTNKGRVYRLKAYEVPEYGRTAKGLPVVNLLKL-DEE
TIQTIIKAK--E-GKYFFFTTRQGLVKRTNASEFHN-RQNGLRALNLKEGDELINVL-TNG-EDIIIGTRLGYSVRFNE--IRQMGRSATGVRGVKLR--
-QVVGAARITDDQEVLIITENGYGKKTLASEYPTKGRGGKGIKTANIT-A-NGPIAGLVTVSQ-EDIMIITNKGVIIRTHISDVSQTGRATLGVKVMRLD
D-KIVTFALVE-
>tr|W7D646|W7D646_9LIST DNA gyrase subunit A OS=Listeria rocourtiae FSL F6-920 GN=gyrA PE=3 SV=1
DEDLIPEEEVAITLTNKGYIKRLPLSTYRSQRRGGRGVQGMGT-EDDFVEHLVATSTHDTLLFFTNTGKVYRAKGYEIPEYSRTAKGIPIINLLGIES-E
KVNAVINLR---DDQYLFFTTKLGVVKRSTLTQFAK-RQSGLRAVELRENDELISVQ-TDG-KKIIIGTKFGQSIYFEE--IRVMGRTAAGVRGIRLR--
EDVVGMEILEDDEKVLVVTENGYGKQTLASQYPLRNRGGMGVKTINIT-EKNGNLVALKTVTE-EDLMLMTIGGVLIRFSVGDISQTGRSAMGVKLIRLD
-DFVATVAKVP-
>tr|H5T2C1|H5T2C1_MELPD DNA gyrase subunit A OS=Melissococcus plutonius (strain DAT561) GN=gyrA PE=3 SV=1
DEDLIEEEKMVVTLTNNGYIKRMANSEFRAQRRGGRGVQGMGV-ADDFVKNLVSCSTHDTLLFFTNNGKVYRAKGYEVPEYGRTAKGIPIINLLGI-DNE
TVQTIISVT--EEGHYLFFTTKNGTVKRTAVTAFSN-RSNGLIAIGLKEDDELVNVI-TSG-QNIIIGTHTGYSTTFKE--VRDMGRTASGVRGIRLR--
-NVVGASLLDENTEVLVITENGYGKRTKAIEYPVKGRGGKGIKTANIT-E-NGPLAGLATVRD-EDILLITNKGIIIRFNAESVSQTGRSTLGVRLIRME
T-KVVTMAVID-
>tr|S0P307|S0P307_9ENTE DNA gyrase subunit A OS=Enterococcus saccharolyticus ATCC 43076 GN=gyrA PE=3 SV=1
DEDLIEEEEIVITLTNNGYIKRVANSEFRAQRRGGRGVQGMGI-DEDFVRTLVSCSTHDTLLFFTNAGKVYRAKGYEIPEYGRAAKGIPVINLLGI-DSE
RIQTIISVS--EEGNYLFFTTKLGVVKRTSVMAFSN-RSNGLIAIGLKEGDELVNVL-TKG-DVMIIGTHKGYSVTFKE--VRDMGRTAAGVRGIRLR--
-DVVGAAVIREGDEVLVITENGYGKRTAGSEYPIKGRGGKGIKTANIT-A-NGPLAGLTTVTE-EDILLITNKGVIIRFSAETVSQTGRATLGVRLMKME
D-KVVTMASVD-
>tr|D2EH11|D2EH11_PEDAC DNA gyrase subunit A OS=Pediococcus acidilactici 7_4 GN=gyrA PE=3 SV=1
DEDLIEEEDVMVTLTHNGYIKRMPTSEFKTQNRGGRGIQGMGV-EDDFIEHLVSTSTHDVLLFFTNAGKVYRMKGYEIPEYSRTAKGIPVINLLGI-DGE
SIQAVINIGD-NEHRYLFFTTLQGVAKRTPVAEFMN-RSNGLKAINLKDGDEVINVV-TDG-QNIIIGTHNGYAISFKE--VRSMGRSATGVRGIRLR--
-NVVGSAVLAPESKVMVITEKGYGKQTPAEEYPIKGRGGKGIKTANIT-E-NGPLAGLVTVEN-EDVMLITDRGVMIRFNVDNVSTTGRSTLGVHVIKTD
N-KVATMAIVE-
>tr|A0A0R2ET17|A0A0R2ET17_9LACO GyrA protein OS=Pediococcus claussenii GN=IV79_GL001444 PE=4 SV=1
DEDLIEEEDVMVTLTHNGYIKRMATSEFKSQKRGGRGVQGMGV-DDDFIEHLVSTSTHDVLLFFTNAGKVYRMKGYEVPEYSRTAKGIPVINLLGI-SDE
TVQAVINVGD-NSKRCLFFTTLKGVVKRTAVSEFLN-RSNGLKAINLKDKDELINVA-TTG-ENMIIGTHKGYAVSFKE--VRTMGRSATGVRGIRLR--
-EVVGVDVLRPDSNVLVITEKGYGKQTPASEYPIKGRGGKGIKTANIT-E-NGPIAGLATVKD-EDIMLITDRGVMIRFNINTVSQTGRATLGVHVIRID
G-KVATMAKVA-
>tr|A0A0R2NJU6|A0A0R2NJU6_9LACO GyrA protein OS=Pediococcus argentinicus GN=IV88_GL000937 PE=4 SV=1
DEDLIEEEDVMVTLTHNGYVKRMATSEFKTQHRGGRGIQGMGV-DDDFIENLISTSTHDVLLFFTNAGKVYSMKGYEIPEYSRTAKGIPVINLLGV-SGE
KIQAVINIGD-NENRFLFFTTLKGVAKRTPVSEFLN-RSNGLKAINLKEEDELINVA-TSG-ENIIIGTHKGYAVSFSE--VRSMGRSATGVRGIRLR--
-EVVGVDILKPDSNVLIITENGYGKQTPAGEYPIKGRGGKGIKTANIT-E-NGPLAGLTTVSE-EDIMLITDRGVMIRFNIDSVSQTGRATLGVHVIRID
G-KVATMAKVA-
>tr|A0A0M2NJQ4|A0A0M2NJQ4_9FIRM DNA gyrase subunit A OS=Catabacter hongkongensis GN=gyrA PE=3 SV=1
IDELIAREDMVVTLTHYGYIKRISLETYRAQRRGGRGVTAMST-EEDFAEQVFVTCTHNQLLFFTNKGKVYMKKCYQIPEG-RTAKGTAIVNMLNLDP-E
KISAVFPIE---KDSNLMIVTKRGVVKKTPFTEYSN-RQNGLKAVNLRDDDELISVM-TDG-KQIIVGTRDGMSIIFSE--VRPMGRVATGVRAIKLR--
-GVVDACISEK-KQILVITEKGYGKRTLASEYRLQSRGGIGLKSMNIT-D-TGKLCGLKVVDT-EDIMLINDAGVVIRMSVEEISLIGRSTQGVRLMRVD
DT-VVCVAKIV-
>tr|U2JZ56|U2JZ56_9FIRM DNA gyrase subunit A OS=Peptostreptococcaceae bacterium oral taxon 113 str. W5053 GN=gyrA PE=3 SV=1
IIELIKEEDVLITLTRGGYIKRIPTNVYKKQNRGGKGIIGMTT-SEDYVDTLFVSSTHDMILFFTNKGKVYSQFAYEIPE-SRTAKGQAIINLLHLEEGE
KVNAVFPVQ-YA-ESCLTFATKKGMIKRTLVSEYENIRKNGIVAIKLVDDDELISVKMTDEKDKAIFITQQGMGIAFP---VRIMGRATQGVRGITLR--
-NVVSFEILE-DKDVLIVSEYGFGKRTSAEQYTIQNRGGKGVYTYKITP-KTGYVVAAKIVN-EDELIMISMQGEVIRLAVKQISE-GKRTSGVKLKDIN
NEKIVAIARYV-
>tr|R5B9C0|R5B9C0_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:226 GN=gyrA PE=3 SV=1
LDDIIQEEDMAVTMTHLGYVKRIAADSYKAQNRGGKGIMAQAT-DEDFVEHLFVTSTHNYIMFFTNTGRAYKIKCYNIPES-RTAKGTAIVNLLQLAG-E
KITAVFPVD---EGEYLVLATKDGVIKKTPMSDFDN-RKGGIIAQNLRDGDELISVL-SKG-DDLLIGTREGKCVRFNE--VRSMGRTATGVRAITLE--
-GVIDVNLIAP-MTVLSITEKGMGKRTDEEEYPLRHRGGKGVIANAIT-E-TGKLACMKVCTD-EDIMMIRDDGTVIRTPVDKISIFSRNTQGVRLMRVD
GT-VASVALAP-
>tr|K5CE34|K5CE34_LEPME DNA gyrase subunit A OS=Leptospira meyeri serovar Hardjo str. Went 5 GN=gyrA PE=3 SV=1
AEDLIADEEVVVQLSEDMFIKRLPMDTFRRQKRGGKGVQGIST-REDFVKKLSSAMTHDNLMLFSNKGRAFLMRVYELPIATKEARGKSLKAVINLNDDE
IITSLFTFR---E-SYLLMVTRDGFVKKIQLDEFTNTKKSGIIAIGLRDGDELIDVA-NPNNFDVFIGSKNGLAIRMN---LRSQGRTASGVTAMKLED-
-DIAGITKVEPGTNLFCVSENGFGKRTDFEEFSTKGRGGKGMTYLKIGE-KNGRAVGIASVK-EDELLVITQSGMAIRVEVKTISMLGRSAMGVKVVNTK
-DFVKDFAVVR-
>tr|W7AQI8|W7AQI8_9LIST DNA gyrase subunit A OS=Listeria aquatica FSL S10-1188 GN=gyrA PE=3 SV=1
DEDLIPEEEVAITLTKKGYIKRLPLSTYRSQRRGGRGIQGMST-EDDFVEHLVATSTHDTLLFFTNTGKVYRAKGYEVPEYGRTAKGIPLINLLGIES-E
QVNAVINLS---DDDYLFFATKHGVVKRSALSQFAN-RQSGLRAVDLRENDELISVQ-TDG-KKMIIATKAGQSIYFPE--IRVMGRTAAGVRGIRLH--
DDVIGMEVLEDDQNVLVVTENGYGKQTPAEQYPLRNRGGMGVKTVSIT-DKNGPLVAMKTVSD-EDIMLMTIHGVLIRFEVETVSETGRSTMGVKLIRLD
-NKVATVAKVP-
>tr|W7CXZ2|W7CXZ2_9LIST DNA gyrase subunit A OS=Brochothrix campestris FSL F6-1037 GN=gyrA PE=3 SV=1
DEDLIEQEDIVITITKNNYIKRLPASTYRAQNRGGRGVQGMAI-EGDFVEQLLATSTHDTILFFTNTGKVYRAKGYEIPEFSRTAKGLPVVNLLGIEK-E
EINAMISIK---QDHFLFFATRNGVVKRTQLSQFTN-RTSGLRAIDLRENDELIRVQ-TNG-NHVIMATHLGQSIHFQE--VRIMGRTAAGVRGIRLN--
ADVVGMEVVKPADKVLIVTENGYGKQTPIEQYSVQGRGGKGVKTVSIT-AKNGPLTNMITVNE-EDLMIMTVEGVLIRMSVDAISETSRSTMGVRLIRLD
-KKVATIAPTE-
>tr|D1JED8|D1JED8_9ARCH DNA gyrase subunit A OS=uncultured archaeon GN=gyrA PE=3 SV=1
ERDFVEEKEVILYLTQRDYVKRLPADIFKQQMRGGKGIAVIEK-EDDKIVNFIRASTRERLIFFTEFGKAYQVKTYEIPPSSRHSKGKPLVNIPGLSIST
EERAVAIPE---EGAYLVFATKRGVVKRSSLAKLKAIRSTGVVAVRTTKGDSLADVVLIAGQNGIILSSKNGKAIFFHE--LREMGRYAAGVRGMRLE--
-EIASVEALDVKSRAVTITEKGYGKRTKLDAYRETHRGGKGVISI--GE-RNGKVVCIKQVKNTDELMVATSDGMVTKISVRSISVQGRNTQGVRIMNVK
-GRVVAVDILS-
>tr|R9MML1|R9MML1_9FIRM DNA gyrase subunit A OS=Dorea sp. 5-2 GN=gyrA PE=3 SV=1
MEDLIPKEDVVITLTKLGYIKRMSNDTFKSQNRGGKGIKGMQT-EEDYVEELFMTHTHHYIMFFTNTGRVYRLKGYEIPEASRTSRGTAIVNLLQLMP-E
KIGAVIPID---DGEYLFMATKKGLVKKTPIKEYAF-RKTGLAAITLREEDELIEVK-TNS-QEVFLVTKYGQCIRFDE--VRPTGRTSMGVRGMNLS--
-RVIGMQLSSQGKELLIVSEKGMGKRTSIEEFTCQNRGGKGIKCYKIT-E-TGNVVGIKSVND-DEIMIINTEGIVIRMKCSGISVLGRVTSGVKLIDLK
G-IVASIAKVR-
>tr|R9MHF8|R9MHF8_9FIRM DNA gyrase subunit A OS=Lachnospiraceae bacterium 3-2 GN=gyrA PE=3 SV=1
MEDLIPKEDVVITMTKLGYIKRMSHDTFKSQNRGGKGIKGMQT-DEDYVEELFISHTHHYIMFFTNTGRVYRMKAYEIPEASRTSRGTAIVNLLQLMP-E
KISAVIELD---DGEYLFMATKRGLVKKTPIKEYEN-RKKGLAAITLREDDELIEVK-TDG-NDIFLVTKYGQCIRFNE--VRPTGRTSMGVRGMNLS--
-RIIGMQLEIQGKELLIASEKGMGKRTDTSEFTCQNRGGKGVKCYKIT-E-TGNVVGVKAVND-DEIMIINTEGIIIRMKCEGISVLGRVTSGVKLINLN
G-TVASIAKVR-
>tr|R7FV83|R7FV83_9FIRM DNA gyrase subunit A OS=Dorea longicatena CAG:42 GN=gyrA PE=3 SV=1
MEDLIPREDVVITMTKLGYIKRMSHDTFKAQNRGGKGIKGMQK-DEDYVEELFMTNTHHYLMFFTNTGRVYRMKAYEIPEASRTSRGTAIVNLLQLMP-E
KISAVIPIE---DDEYLLMATKKGLIKKTPIKEYAN-RKTGLAAITLREEDELIEVK-TDS-HDVFMVTKYGQCIRFNE--VRPTGRTSMGVRGMNLV--
-RVIGMQIDSQGTELLIVSEYGMGKRTSIDEFTAQNRGGKGVKCYKIT-E-TGNVVGVKAVDD-NEIMIINTEGIIIRMKCDGISELGRVTSGVKLINLP
G-KVACIAKVR-
>tr|R7IMU5|R7IMU5_9FIRM DNA gyrase subunit A OS=Roseburia sp. CAG:303 GN=gyrA PE=3 SV=1
MEDLIPVENTVIAMTKLGYIKRMTVDNFKSQNRGGKGIKGMQT-NDDYIVELQMTTTHHNLMFITNTGKAYRIKAYEIPDASRTSRGVAIINLIQMEP-E
KVTAMFPVK---ENSFLTMVTKNGIVKKTPMVEYAN-RKRGLQAICLREDDELIEVK-TLN-DIVMLVTKYGQCIKFKV--IRRTGRNSIGVRGINLD--
-HVIGMQLESQGECLLLVTENGMGKRTLASEFTVQHRGGKGVKCYRIN-D-TGNIIGVKSVDD-NEIMLITTEGIIIQMQVSGISRLGRITSGVKLMDIS
D-VVASIAKVR-
>tr|C3WFJ3|C3WFJ3_FUSMR DNA gyrase subunit A OS=Fusobacterium mortiferum ATCC 9817 GN=gyrA PE=3 SV=1
PEDLIKDEEVILTFTNKGYVKRMELSKYKAQKRGGRGVASQNT-EDDFVENIESAMNLDTLMIFTNQGRVYNIKVYEIPES-KQSRGRLIGNIINLKTDE
KIRAIIKTR-F--ENEVIFVTKDGTVKKTNLSEFKNINSSGLKAIKLKENDDIIYVGLIEDNEQLLIATQAGYSIRFS---LRATGRDTMGVKGLTLR--
-TVVSALLIKDNSSILTITENGYGKRTKIDEYPLQSRIGKGVINLRCSA-KTGSVVSVLSVS-DEELMAITSSGVVIRIAVDDIVL-GRATQGVIIMKVH
KDKVVSITRVK-
>tr|U7VDG4|U7VDG4_9FUSO DNA gyrase subunit A OS=Cetobacterium somerae ATCC BAA-474 GN=gyrA PE=3 SV=1
PEDLIKDDSVLVTITNRGYVKRMELDKYKAQKRGGKGVSTQNT-EDDFVERMEVMSNLDTMMIFTDKGRVFHLKVYQIPESSKQARGRLIGNLIKLKE-E
KVREIIKIRD----KELVFVTRDGMVKKTNLSEYKN-NTAGLKAIKLRDGDDIIFVG-LPVKEQIFLATKLGHSIRFAK--VRPTGRDTSGVKGISLR--
DKVISALLIDDNETILTITENGYGKRTRVDEYPLQSRSGKGVINIRCS-D-NGEVVAVKPVKE-EELMVITSSGIVIRTSVNQISIIGRATQGVKIMRVN
SSKVVSIASFK-
>tr|D1AIT4|D1AIT4_SEBTE DNA gyrase subunit A OS=Sebaldella termitidis (strain ATCC 33386 / NCTC 11300) GN=gyrA PE=3 SV=1
IEDLIKDEEVVVTLTDKGYVKRTPIDVYRAQKRGGIGVSATNI-EDDIIKDMYIAKNLDSLLIFTTKGKVHDIKVYEIPEASKQARGRLISNIIKLQE-E
MVSTIIKVR----DKDIFFVTRKGVVKKTNLELFAS-NKAGIKAIGLKDDDELIFAG-TSGKDEIFLATREGFAIRFSE--VRSMGRTASGVKGITLR--
DVIVAGAIIYAGKTILTISEEGYGKRTKLEEYRLQSRGGKGITNLKKN-T-TGKISDVKIVDS-SEIMLITSEGTLIRTQVNSISIIGRATSGVRIMKVR
N-KVASTVKIT-
>tr|V9HJF7|V9HJF7_9FUSO DNA gyrase subunit A OS=Fusobacterium ulcerans ATCC 49185 GN=gyrA PE=3 SV=1
PEDLIKDENVILTLTNKGYVKRMEVSKYKAQKRGGKGVASQNT-EDDFVESIESASNLDTLMIFTNQGRVFNIKVYEIPES-KQSRGKLMSNIIRTREDE
KIRAVIKTR-F--ENEVVFVTKEGLIKKTNLDEFKNINNSGLKAIKLKEEDDIIYVGLIEKQEQVFIATKQGYSIRFN---VRPTGRDTMGVKSITLR--
-SIVSALLIKDEGSILTVTENGYGKRTRIDEYPLQARSGKGVINIRCNA-KTGAVVSVLPVT-GEELMAITSSGIVIRMPLDTIAL-GRATQGVIIMKVD
AEKVVSITRVK-
>tr|W4F8D9|W4F8D9_9BACL DNA gyrase subunit A OS=Viridibacillus arenosi FSL R5-213 GN=gyrA PE=3 SV=1
DEDLIPRENSVITLTHNGYIKRLPANTYRSQKRGGRGVQGMGT-DDDFVEHLMNTSTHDTIVFFTSKGKAFRAKGYEIPEYGRTAKGLPIVNLLSVDK-E
QVTAMIRVP---DDAYFIFTTRTGVTKRTPVSYFAN-RNNGLIAISLREDDELISVR-TDG-KEIIIGTRNGMLVRFNE--IRSMGRTAAGVRGIRLK--
DDVVGMEMIEPGQEILVVTEKGYGKRTPEEEYRIQSRGGVGIKTCQIT-DKNGPLSAVKTVDS-EDLMLITINGMLIRMDINDISVTGRSTQGVRLIRLG
-ELVATVAKVA-
>tr|A0A078LZ47|A0A078LZ47_9BACI DNA gyrase subunit A OS=Lysinibacillus sp. 13S34_air GN=gyrA PE=3 SV=1
DEDLIPQEDSVITFTNNGYIKRLATNTYRSQKRGGRGVQGMGT-EDDFVEHLLFASTHDTILFFTTKGKVFRAKGYEIPEYSRTAKGLPIINLLNLEK-E
SVTAMIRVP---EDAYFIFTTKTGVTKRTAVSNFAN-RTNGLIAISLREDDELMAVR-TDG-QEIVIGTRQGMLIRFLE--IRSMGRTAAGVRGIRLR--
DDVVGMEIIESGQDILVVSEKGYGKRTNEDEYRTQTRGGIGIKTMQIT-DKTGPLVAVKTVTE-EDIMLITVEGMLIRMDVNDISTIGRNTQGVRLIRLA
-EYVATVAKVK-
>tr|A0A0P7KSG3|A0A0P7KSG3_9BACI DNA gyrase subunit A OS=Lysinibacillus sp. ZYM-1 GN=AO843_06255 PE=4 SV=1
DEDLIPVENSVVTLTHNGYIKRLAANTYRSQKRGGRGVQGMGT-EDDFVEHLMNTSTHDTILFFTSKGKVFRAKGYEIPEFGRTAKGLPIVNLLNIDK-E
KVTAMIRVG---EDAYFIFTTKTGVTKRTPVSQFAN-RTNGLIAISLREDDDLISVR-TDG-KQIIIGTRDGMLVRFQE--IRSMGRTAGGVRGIKLR--
GDVVGMEIIEPGQEILVVTEKGYGKRTSEDDYRLQSRGGVGLKTMQIT-DKNGPMVAVKTVDS-EDLMLITINGMLIRMDINDISLIGRSTQGVRLIRLG
-DLVATVAKVE-
>tr|D4W7Q6|D4W7Q6_9FIRM DNA gyrase subunit A OS=Turicibacter sanguinis PC909 GN=gyrA PE=3 SV=1
DEDLIPEEQVIITLTNNGYIKRQPISTYRSQNRGGRGVQGMGT-DDDYVKELLSTSTHDYLLFFTNKGKVYQKKAYTIPEG-RTAKGLPIVNIIEIAQ-E
EISAIIPVK--E-NEFLFFATRTGVVKRTTLSAFGN-RTNGLIALSLREDDELIGVR-TTG-NDIVIASSGGKLVWFEE--VRSMGRTAAGVRGINLE--
-GAVGMEIVTE-QEILIVSEKGFGKRTPISEYRKTSRGGKGVKTINIT-D-NGSLVAMKTV-G-EDLLIVTNKGIIIRTPISQISQTGRATQGVTLIRLT
DQ-VSSVALVE-
>tr|A0A0M3RCQ8|A0A0M3RCQ8_9BACI DNA gyrase subunit A OS=Bacillus sp. FJAT-22090 GN=gyrA PE=3 SV=1
DEDLIPVENSVLTLTNKGYIKRLPANTYKSQKRGGRGVQGMGT-EDDFVEHLLYTSTHDTILFFTNKGKVYRARGFEVPEYGRTAKGLPIVNLLGIER-E
QVTAMIRMA---EDNYFIFTTKHGVTKRSPVSGFAH-RANGLIAISLRDEDELIAVR-TDG-KQIIIGTRQGKLVRFEE--IRSMGRTASGVRGVRLK--
DDVVGMEIIEPGQEILVVTENGYGKRTPESEYRLQSRGGMGVKTCQIT-EKNGPLCAVKAVDT-EDLMLITINGMLIRMDVNDISVTGRSTQGVRLMRLA
-DLIATVAKVK-
>tr|A0A0P6WNR6|A0A0P6WNR6_9BACI DNA gyrase subunit A OS=Bacillus vietnamensis GN=AM506_19880 PE=4 SV=1
DEDLIPRENIVVSLTHNGYIKRLPVSTYRSQKRGGRGIQGMGT-GEDFVENLLTTSTHDTILFFTNKGKAYRAKGYEIPEFSRTAKGLPIINLLGVEK-E
WINAMIRVE---DDWYLFFTTKQGISKRTPVSDFAN-RTNGLIAINLRENDELISVK-TDG-KDMIIGTKQGMLIRFPE--VRSMGRTATGVKGINLS--
DDVVGMEILEDKSDVLVVTVNGYGKRTPASEYRVQTRGGKGLKTCNVT-ERNGELVSVKAVTE-EDLMIITAHGVLIRMDVNDISTTGRNTQGVKLIRLQ
-SFVSTVAKVE-
>tr|A6CPM5|A6CPM5_9BACI DNA gyrase subunit A OS=Bacillus sp. SG-1 GN=gyrA PE=3 SV=1
DEDLIPRENIILTLTHNGYIKRLPVSTYRSQKRGGRGIQGMGT-EDDFVEHLLTTSTHDTILFFTNKGKAFKAKGYEIPEFSRTAKGIPIINMLGVDK-E
WVNAMIRIE---DDWYLFFTTKQGISKRTPVSDFAN-RTNGLIAINLRENDELISVK-TDG-KDIIIGTQKGMLIRFPE--VRSMGRTATGVKGINLD--
EDVVGMEILEEKDDVLVVTEKGFGKRTPAEEYRIQTRGGKGLKTCNIT-DRNGELISVKAVTE-EDLMLITAHGVLIRMDVNDISITGRNTQGVKLIRLD
-NSVATVAKVE-
>tr|G2MH37|G2MH37_9ARCH DNA gyrase subunit A OS=halophilic archaeon DL31 GN=gyrA PE=3 SV=1
HEDLIPESEQVVVMTEDDYIKRMELSAFRAQNRGGKGIIGTDL-EGDSVASVFVANSHDYLLCFTNHGQVYELKTYQVPEMSRTARGKSAVNLLDLDEGE
QLEAVVNTA---DDQFLTMVTRDGYIKRTGVSEFQNILSTGIRAIRLEDGDSLADVEVTDGTQDVVIATKGGMSIRFDE--ARAMGRTARGVRGVKLE--
-EVAAVAGIDENSWLLTVTENGYGKRSNLDAYRTQSRNGKGLIDI--NE-RNGPVSALEAVGPGDHLVMMSEEGQIMRSPVEDLSIVGRNTMGVIVMRVD
-GRVAAVDVIE-
>tr|A0A0P7GC22|A0A0P7GC22_9EURY DNA gyrase subunit A OS=Halolamina pelagica GN=SY89_02180 PE=4 SV=1
HEDLIPESEQVVVMTEDDYIKRMELSEFRAQNRGGKGIIGTGL-EGDAVASVFVANSHDYLLCFTNHGQVYKLKTYEVPEMSRTARGKSAVNLLDLDDDE
QIESVVN---IEEQQFLTMVTRGGYIKRSGVSEFQNILSTGIRAISLEDGDRLADVE-TDGAQDVVIATRNGMSIRFDE--ARAMGRTARGVRGVDLE--
-DVAAVAGIDENSWLLTVTENGYGKRSDLDAYRVQSRNGKGLIDI--NR--NGGVTALDAVGPGDHLVTMSEQGQIMRCPVEDLSIVGRNTMGVTVMDLE
-GRVAAVDVVD-
>tr|C0BFK2|C0BFK2_9FIRM DNA gyrase subunit A OS=Coprococcus comes ATCC 27758 GN=gyrA PE=3 SV=1
TEDLIPREDVVITMTKMGYIKRMSNDTFKSQNRGGKGIKGMQT-DEDYVEELFMTNTHQYIMFFTNTGRCYRLKGYEIPEAGRTSRGTAIINILQLQP-E
KITAMIPIK---EGDYLFMATKKGLVKKTPILDYAN-RKTGLAAITLREDDELIEVK-TDD-RDVILVTQYGQCIRFHE--VRSTGRTSMGVRGMNLS--
-RVVAMQLDAQGEELLIVSEKGMGKRTRMEEFTAQNRGGKGVKCYKIT-E-TGNVVGAKAVGD-DEIMIINTDGIVIRMECAGISVLGRITSGVKLINLK
H-EVASIAKVR-
>tr|K4MTS0|K4MTS0_9EURY DNA gyrase subunit A OS=Methanolobus psychrophilus R15 GN=gyrA PE=3 SV=1
DEDLIPDEEVVITITNSGYIKRLLVDTYSQQHRGGKGIMGMET-DEDFVTDIFVASTHNYILFFTSKGRVYWQKVYEIPEGSRQSRGKAIVNLLELSE-E
SVTAMIPVS----DSYLFMATRMGTVKKSSLSDFSN-RKAGIIALNLDEGDELVNVA-TDG-KEMVMVSRHGKAIRFSE--VRPMGRSARGVRGMRLE--
DLVVSLDVVDE-ASLLTVTENGFGKRTEFGEYRTLHRGGQGVITIVTS-L-NGPVMNVKAVKT-DEIMLTSSEGIIIRIPVKDIRIQGRNTQGVKIMDVR
K-KVVGVARIR-
>tr|F7XMZ5|F7XMZ5_METZD DNA gyrase subunit A OS=Methanosalsum zhilinae (strain DSM 4017 / NBRC 107636 / OCM 62 / WeN5) GN=gyrA PE=3 SV=1
DEDLVPEEDVVVTITHDGYIKRLPQDTYSSQHRGGRGILGIET-EGDFVENIFVASTHDDLLFFTNKGRVYCQKVYEIPQASRHSRGKAIVNLLDLK--E
FITAMIPIS----DSYLLMATKQGTVKKCQLSEFSN-RKTGIIAISLNDEDELSNVI-TDS-RDVILVSRNGKAIRFSE--VRTMGRTARGVRGMKLD--
DMVVSIDVVDEDSTLLTVTEKGFGKRTRFGEYRTMRRGGRGVMTIVTS-I-NGHVVNIKSVKN-DEVMLTTSEGIIIRIPVKDIRIQGRNTQGVKIMHVR
D-KVVDVAKIR-
>tr|Q12YR8|Q12YR8_METBU DNA gyrase subunit A OS=Methanococcoides burtonii (strain DSM 6242 / NBRC 107633 / OCM 468 / ACE-M) GN=gyrA PE=3 SV=1
DEDLIPVEEVIVTITNSGYIKRMPVDTYSQQHRGGKGVIGMET-EQDVVEDIFISSTHDYLMFFTNRGKVHWKKVYGLPEGSRQSKGKAVVNLLDLAE-E
SVTATITVK----DKFLFMATRMGTVKKTPLSDFSN-RKAGIIALKLDEGDELVNVA-TDG-KEIMMVSRHGKAIRFCE--VRPMGRTARGVRGMRLT--
DIVVSLDIVDL-TKLLTITENGYGKRTTFDEYRGMKRGGQGVITIVTS-L-NGPVINVKAVKE-DEVMVTSSEGIFIRIPVKDIRAQGRNTQGVKIMNVR
G-KVVGVARIK-
>tr|D7E9I1|D7E9I1_METEZ DNA gyrase subunit A OS=Methanohalobium evestigatum (strain DSM 3721 / OCM 161 / Z-7303) GN=gyrA PE=3 SV=1
EEDLIPEEDVLITITNSGYIKRLPVTTYSKQHRGGRGVAGINV-DDDFVEDVFVASTRDYLLLFTNKGRVNCKKVYEIPQGSKQSRGKALVNLFELEN-E
AVSSMITVK----DWNLLMATKYGTVKKTPLSSFKT-KKSGLIAINLNENDELVNVI-TDG-NDIILVSSTGKAIRFAE--VRPMGRAAQGVRGIRLN--
DRIISMDTISDNAKLLTITQNGYGKRTKFEEYRRMNRGGRGVTTIQMT-P-NGPVVNVKTVRD-DDIVVTSYQGLVIRIPVKDIRVQGRNTQGVKIMNMR
-NKVIGVARIK-
>tr|L0KX58|L0KX58_METHD DNA gyrase subunit A OS=Methanomethylovorans hollandica (strain DSM 15978 / NBRC 107637 / DMS1) GN=gyrA PE=3 SV=1
LEDLIPQEDVIVTITNSGYVKRLPVSTYSQQHRGGKGVIGMET-EEDFVENIFVASSHDYIMFFTNKGRLYWKKVYEIPEGSRQSKGKAIVNLLELGE-E
YVTAMIPVK----DQYLFMATRSGTVKKTSLSDFSN-RKGGIIAVTLLEDDELVNVA-TDG-KDVVLVSRHGKAIRFSE--VRSMGRSAQGVRGIKLE--
DKVVSLDVVDE-STLLSITENGFGKRTEFGEYRTMRRGGMGVITIVTS-L-NGPVVNVKAVRE-DEVMITSSEGIVIRIPVTDIRIQGRNTQGVKIMDVR
G-KVVGVARIE-
>tr|A0A0E3SRU3|A0A0E3SRU3_METMT DNA gyrase subunit A OS=Methanococcoides methylutens MM1 GN=gyrA PE=3 SV=1
DEDLIPEEDVVVTITNHGYIKRMPIDTYSQQHRGGKGVIGMET-EEDFVEDIFVASTHDYLMFFTNRGRVHWQKVYGIPQGSRQSKGKAIVNLLELAE-E
SVTAMIPVK----DKYLFMATRSGTVKKSSLSDFSN-RKAGIIAIKLDEGDELVNVA-TDG-REIMMVSRHGKAIRFSE--VRSMGRAARGVRGMKLA--
DIVVSLDIVDS-SKLLTITENGYGKRTSFDEYRGMRRGGQGVITIVTS-L-NGPVINVKAVHD-DEVIITSSDGIIIRIPVKDIRSQGRNTQGVKIMNVK
G-KVVGVARIK-
>tr|W9DTR5|W9DTR5_METTI DNA gyrase subunit A OS=Methanolobus tindarius DSM 2278 GN=gyrA PE=3 SV=1
TEDLIPEAEMVVTITNSGYIKRLPVDTYSKQHRGGKGVIGMDT-DEDFVVDIFVASTHDYIMFFTNQGRVHWRKVYEIPEGSRQSRGKAIVNLLELGE-E
LVTAMIPVN----DEFLFMATRTGTVKKSQLSDFSN-RKKGIIAISLVEGDELVNVA-TDG-REMMMVSQHGKAIRFPE--VRVMGRSAKGVRGMNLE--
DMVVSLDVVDD-TALLTITENGFGKRTEFDEYRAMHRGGRGVITIVTS-L-NGPVINVKAVHD-DDVILTSSEGIIIRIPVKDVRIQGRNTQGVKIMNVR
S-KVVGVARIR-
>tr|A0A094RIP7|A0A094RIP7_9ACTN DNA gyrase subunit A OS=actinobacterium acMicro-4 GN=gyrA PE=3 SV=1
NEDLIPEEEMVITVTRGGYIKRTKSASYRSQHRGGKGVKGA-QRADDVVEHFFVTTTHRWLLFFTTTGRVYRTKAYEVQEAGRDAKGQHVANLLALQPGE
DIAQILDIA---AQ-YLVLTTKQGMVKKTELTQYDT-RVGGIIAINLKDDDQLVSAM--NDGDDILLVSRGGMSLRFTT--LRPMGRSTAGVIGMHFR-E
-DLLSASV-VTEGFVFVVTEGGYAKRTAVDQYRAQQRGGLGIKVAKLS-E-RGGLAGALIVGD-DEVLVVLESGKVVRSGVNEVPA-GRDTMGVVFARMD
-ETVLGIARNQ-
>tr|M4ZVR9|M4ZVR9_9ACTN DNA gyrase subunit A OS=Ilumatobacter coccineus YM16-304 GN=gyrA PE=3 SV=1
IEDLVDDKELVIVMTQAQYVKAVPAASFKTQGRGG-G--SGK--DD-IVRHVIFTTAHAHLLFFSNRGKVYRLRALDIPEE-RTAKGMPMVNLL-PQD-E
K--AIIDTR---GDRYLFFATEQGTVKKTTFGAYDT-R-DGLIAINLK--DRLMK---TD---DIFMVTKRGMTI------VRSMGRTAGGVRGIKLKN-
-AVVSVDVARD-TSILMVTESGYGKRTEL-QFN-QGRGGQGVIGI---TGKKGEV-DAFMVG-DDDIVAVSKSGITIRMPV-EIST-GR---GVKVMNMD
G-IVGSVAPIL-
>tr|A0A075GSM7|A0A075GSM7_9EURY DNA gyrase subunit A OS=uncultured marine group II/III euryarchaeote KM3_195_B08 GN=gyrA PE=3 SV=1
LEELIPNDRVVVTITNKGYIKRLEVDEYRKQRRGGKGVIGTGT-EEDFVRDVIVTKNHNYMLFFTDKGRVFWLKTYRIPEAGRYSTGRTLVNLLNIK-DE
KVTSWIS---FP-NAYFVMATRNGIIKRISLEAFSRPRKGGIIAITLKEGDGLVDVL-SNGSQEVILATKFGQAIRFKE--ARELGRTGQGVIGIRLK--
-DGVVGMAISREPTLITITENGYGKRTAIQEYRVQSRGGSGVINI--ER--NGSVVGVRAVKDGYDAILITSKGQVIRIPVSGVSVIGRNTQGVRLMRLA
-KKVVSFAIVR-
>tr|M0CPJ9|M0CPJ9_9EURY DNA gyrase subunit A OS=Halosimplex carlsbadense 2-9-1 GN=gyrA PE=3 SV=1
NEDLIPEEDVVVVITEDDYIKRMPVDRFDPQGRGGKGIIGADP-EGDRVSKVFRANTHDYLLSFTNQGQVYKLKTYEIPEMSRTARGKSAVNLIDLDDGE
EITAVVNTD----EESIAMVTRDGYVKRTNAEEFENILSTGIIAADLEEGDELVDVEVTDRTKDLVIATEQGMTIRFDE--AREMGRNARGVGGIDLQ--
-HVAGMVATDEDRCLLTVTRNGYGKRTPLTEYRRQSRYGKGLIDI--DE-RNGPVSTVKAVRTDDHLMIMSERGQIMRIRAGDVSEVGRNTKGVVVMKLE
-GQVASVDVVP-
>tr|K9UB50|K9UB50_9CHRO DNA topoisomerase (ATP-hydrolyzing) OS=Chamaesiphon minutus PCC 6605 GN=Cha6605_0142 PE=4 SV=1
IIETEPGQPVTVEITHQGYIRRLSKTGSKLN-------------ND-FVTKTYQTNTEAELILVTSDGKAYPLRIRDIPPL-GN-DRGTLTSLIPALD-E
-RVFSLPTP--DDMQQLLLLTAQGKIKRILIQELSG-T-RGTTLIKLR--DKLHT---T----EIVIATSGARIL------IPLMGRVSQGIQ-LKVG--
-RIVGCIPVNS--EIVLISRQGYAKRIPI-AIR-VQTGNMGTHAM--AKT---DL-YINVPA----LDLVTTTHRHELVAI-RVQT-GK---GDKLVELA
N-EIMFVN----
>tr|A0A0G1WCY4|A0A0G1WCY4_9BACT DNA gyrase subunit A OS=Microgenomates (Beckwithbacteria) bacterium GW2011_GWC2_47_9 GN=gyrA PE=3 SV=1
DEDLEPEEACLVTMTKTGYIKRMPTTTYRSQRRGG-G--TMA--ED-EVSRMFTTNTHDTLLIFTNKGRVFKLKVYEIPQA-RQAKGQAIINLI-NDD-E
T--SVITLA--TDKGYLLMVTRQGIIKKTATPQFAN-R-NGIIAIKLD--DQLVW---TD---QIALISHEAKAI------ARPLGRSAKGVRGINLTK-
-DVVGMAVYRPFNDLLVVMEKGLGKRTNI-DFP-QKRAGKGVKVA---SDKTGKV-SAHLVT-METVAITSKKAQVIKLPL-NIKR-GR---GVILMRFA
P-SVAAVALL--
>tr|A0A0R1YN54|A0A0R1YN54_9LACO GyrA protein OS=Lactobacillus amylophilus DSM 20533 = JCM 1125 GN=FD40_GL001478 PE=4 SV=1
DEDLIEREDVLLTLTHNGYIKRLPVDEFKVQNRGGRGIQGMGV-DEDFIEHLIFSSTHDYLLFFTNTGKVYSKKAYEIPEFGRSAKGIPIINLLNV-EGE
QVQAVINIS----DKYLFFVTKLGTVKRTEVAEFTN-RKSGLRALTLKEDDELSNVI-TDG-QIIFIGTHHGYAVTFKE--IRSMGRTASGVRGIRLR--
-NVVGSEVLRPDSEVLVISENGYGKRTPSSEYPVKGRGGKGIKTANIT-E-NGPLAGITIVDT-EDLMLITDAGVLIRFKVANVSQTGRATLGVRLIRVD
G-KVAGMTKVP-
>tr|F4KUQ9|F4KUQ9_HALH1 DNA gyrase subunit A OS=Haliscomenobacter hydrossis (strain ATCC 27775 / DSM 1100 / LMG 10767 / O) GN=gyrA PE=3 SV=1
MEDMIKEEEVVITISHLGYIKRTPVSEFRQQSRGGRGSRGSKT-DEDFIEHMFVTNTHHYLLLFTSAGRCYWLKGYEIPEAAKTATGRAIQNILAIPKED
KVKAFIVIEV--DNHYIMFCTQQGVIKKTPVEAFSR-RAGGINAITINEGDQLLEAWLTGGNHEVFLASRRGYAVRFN---VRSMGRSAAGVRGMTLADG
-DVVGMVCIAPESTLLVVSEKGNGKRSEVEEYRLTKRGGKGVKTIQITD-KTGMLVAIKSVK-DDDLMITNRSGIIIRMAIGGLRVMGRATQGVRVIRLD
-DDIADVTVVK-
>tr|M9L863|M9L863_PAEPP DNA gyrase subunit A OS=Paenibacillus popilliae ATCC 14706 GN=gyrA PE=3 SV=1
DEDLIPQEDVIITITHSGYIKRLPVTTYRSQKRGGRGVVGMDT-DNDFVEHLFVTNSHHYLMFFTDKGKVYRIKAYEVPGLSRTSRGTPIINLIQIEQ-E
AVNAVIPVK---ADKFLFFATRYGIVKKTPLDDYVN-RKGGLIAINLREDDDLIGVR-TDG-QEIIMGTSNGMSIRFPE--VRSMGRSATGVKGITLD--
-DVIDMDVVSEDNDVLIVSSKGYGKRTPMSEYRIQSRGGKGIKTINVT-D-NGPVIGLKVVQE-EDLMIITSLGTIIRMSMAGISQMGRYAQGVKLINIR
D-SVATVSRCD-
>tr|D7CPP2|D7CPP2_SYNLT DNA gyrase subunit A OS=Syntrophothermus lipocalidus (strain DSM 12680 / TGB-C1) GN=gyrA PE=3 SV=1
AEDLIEEESIVVTLSNRGYIKRQPLSTYRSQRRGGKGVTGTAI-SEDFATDIFVTTTLSTLLFFTNHGRVYSLKAYQVPES-RQSRGTPVINFLRLNP-E
KVNTVISVN---AGQHLVMATRTGMVKKVPIDEFRQ-RRSGIIAINLRNQDELVGVQ-IYK-DRLVLVTGRGYSIVFDE--VRVMGRGAAGVRGISLE--
-GVIDIDKYK--ADMLLVTERGYGKRTSLQELRLQKRGGKGLKTIQIS-E-TGELVGGKAVFK-EEFVALTGAGFVIRLKVDDVPRQKRYSRGVVVMRCE
ND-IVSIARFK-
>tr|F5SHF9|F5SHF9_9BACL DNA gyrase subunit A OS=Desmospora sp. 8437 GN=gyrA PE=3 SV=1
DEDLIPEDEVTILMTHRGYIKRMLLSGYRAQRRGGRGVSGMGT-EDDFVQHLFVTNSHNYLLFFSNKGKVYRMKAYEVPELSRTARGTPIINLIQIDQ-E
YIEAVIPVR----DSYLFFGTKFGVVKKTPLEEFGH-RRNGLFAINLREGDELVGVR-TDG-QEIMLGTRRGMSIRFPE--VRQMGRTATGVKGIALG--
-DVVGMEVVDPEREVVVVTSKGYGKRTPLSEYRTQSRGGKGIKAQNVT-K-KGHVVGLKVVSD-EDLMIVTDSGVVIRMNIDGISRMGRYAQGVKLISVK
D-EVASLARVP-
>tr|K4ZPL0|K4ZPL0_PAEAL DNA gyrase subunit A OS=Paenibacillus alvei DSM 29 GN=gyrA PE=3 SV=1
DEDLIPQEDVIITISHSGYIKRLPVTTYRSQKRGGRGVVGMDT-DNDFVEHLFVSNSHHYLMFFTDKGKVYRIKAYEIPDLSRTARGTPIINLIQIEQ-E
TISAVIPVV---SDKYLFFATQQGIVKKTPLDDYVN-RKGGLIAINLRDDDALIGVR-TDG-QEIIMGTKMGMSIRFSE--VRSMGRSATGVKGITLD--
-DVIDMDVVNKDNDVLIVTAKGYGKRTPMEDYRIQSRGGKGIKTINVT-D-NGAVVGLKVVQE-EDLMIITASGTIIRTSMSGISQMGRYTQGVKLINIR
D-SVSTVSRCD-
>tr|A0A074LJF2|A0A074LJF2_9BACL DNA gyrase subunit A OS=Tumebacillus flagellatus GN=gyrA PE=3 SV=1
EADLIPVEDVVITITHQGYIKRLPANTYRSQKRGGRGVTATGM-EEDFVEHLFTTSSHNYLLFFTNRGKAYRIKAYEVPEFGRAAKGTPIINVLNIEQ-E
MVSAVIPLES-ANGPFLFLATRRGIVKKTPLTAYQN-RKAGLIALTLKDEDELIGVK-TDG-RNIILGTRNGMSVHFPE--VRSMGRNAAGVKGIELD--
-GVIDMDVTNDNCHVLVVSSKGYGKRSPIDSYRIQGRGGRGLKTIDRT-E-TGHIAGLKVVTE-DDIMVITNTGVVIRMAVNTISELSRITQGVKLITLH
EEEVSTVARVP-
>tr|W8YNM2|W8YNM2_9BACL DNA gyrase subunit A OS=Paenibacillus sp. P22 GN=gyrA PE=3 SV=1
DEDLIPREDVVITITHSGYVKRLPVSTYRSQRRGGKGVIGMDT-SDDFVEHLFVSNTHHYLLFFTDKGKVYRLKAYEIPDLSRTARGTPIINLLQIEQ-E
TVNAVIPVE---PDCYLFFGTRQGIVKKTPLDDYSN-RRVGLIAINLREDDDLISVK-TDG-QEIIIGTADGMSIRFPE--VRSMGRSATGVKGIALD--
-DVIDIDVVDPEQEVLIVTAKGYGKRTPVSEYRTQSRGGKGIKTLNVT-E-NGPIAGLKMVEG-EDLMIMTASGTMIRMNMDTISSMGRNTQGVRLINIR
E-SVATVTRVA-
>tr|C6IWT3|C6IWT3_9BACL DNA gyrase subunit A OS=Paenibacillus sp. oral taxon 786 str. D14 GN=gyrA PE=3 SV=1
DEDLIPQEEVVITITHTGYIKRLPVTTYRSQKRGGRGVVGMDT-DNDFVEHLFVTNSHHYLMFFTDRGKAYRLKAYEIPELGRTARGTPIINLIQIEQ-E
TVNAVIEVE---DNKYLFFATKQGIVKKTPIEDYIN-RKGGLIAVNLREDDTLIDVK-TDG-EEVIMGTAQGMSIRFPE--VRSMGRAATGVKGITLD--
-GVIGMDVVVPGQDVLIVTANGYGKRTPISEYRTQSRGGKGIKTINVT-E-NGTVVGLKVVKE-EDLMIITASGTLIRTSMEGISTMGRNTQGVKLINIR
D-TVATVCRTD-
>tr|F4XIF5|F4XIF5_9CYAN DNA gyrase subunit A OS=Moorea producens 3L GN=gyrA PE=3 SV=1
DTDLIANEKAVILLTEQGYIKRMPVDEFRAQARATRGKAAARI-DDDEVEHFFTCCDHDSILFFSDRGVVYSLRAYQIPAVSRTARGVPIVQMLPIPHEE
KITSIVPVS---DDEYLVMLTHKGYIKKTALDAFSKIRANGLIAISLGEGDQLRWVLRAREEDSIIIGSRHGMAIHFKC--LRPLGRATRGVKAMKLK--
-DLIGMDILSGGPWVLIVTMGGYGKRVPVSQFRLQNRAGMGVRSTKFP---KDQLAALQVVN-GDELMIVTSRGIIIRQAVDAISPQSRMATGVRVQKLD
-EAIAAVALVP-
>tr|B4VPJ9|B4VPJ9_9CYAN DNA gyrase subunit A OS=Coleofasciculus chthonoplastes PCC 7420 GN=gyrA PE=3 SV=1
DIDLIANEKAVILVTEQGYIKRMPIHSFAAQARATRGKAAARM-EDDGVEHFLTCCDHDSLLFFSDRGVVYSLRAYQIPAASRTARGVPIVQMLPIPHDE
KITSVVPVS---DDVYLVMLTRKGYIKKTALDAFSNIRANGLIAISLGEGDQLRWVRLCRAEDSIIIGSSQGMAIHFKA--LRPLGRATRGVKAMKLR--
-ELISMDILPAGPWVLVVTTGGLGKRVPVSQFRLQNRAGMGLVTIKF--K-KDKLAALRVVN-GDELMMVTMRGIIIRQALDAISPQSRMATGIRVQRLD
-EAIAAVALVP-
>tr|R7BA61|R7BA61_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:505 GN=gyrA PE=3 SV=1
VEDLIDEETCVFTLSNLNYVKRTPLMTYKSQNRGGRGIVGMQT-DEDFVKDLFLCSTHDTILFFTDHGRVYRLKGYEVPE-GRTARGMAIVNLLEIAPDE
SVTAVIPVK-FE-DRYLVMLTKQGLIKKTDMASYSNIRKGGLIAINLREDDSLISVMTTEGEDEILAATRNGMGIRFS---VRPMGRTATGVKAISLR--
-YLVSAIKMS-TAKVLNVTEKGFGKQTLPEEFKVQYRGGMGVKIHQLTE-KTGLLTGVLMLE-NEEIMLITSEGVIIRLRGADIST-GRVSQGVKLMNLD
GVSVVGIAKIT-
>tr|N1ZIG6|N1ZIG6_9CLOT DNA gyrase subunit A OS=Clostridium sp. ASF356 GN=gyrA PE=3 SV=1
DEDLIDEETSVFTLSHLNYIKRTPLMTYKSQKRGGRGIMGMNT-EEDFVKDLFLGSTHDYILFFTNKGRVYRLKGYEVPEG-RTARGNAIVNLIEISNEE
TITAMIPVK---QDSYLVMITKEGIIKKTDMMSFSN-RKGGLTALSLKEEDNLIAVL-TNG-DEILVATKNGMGIKFHE--VRPMSRQAMGVKAITLK--
-NVVSSVKIT--TQVLNVTEKGYGKRTNSEDFNVQYRGGKGVKIHQLT-E-TGLLTGVLVIDK-EELMLITSEGVIIRLRGNEISSLGRVSQGVKLINLN
ENSVVGVAKIS-
>tr|R5A978|R5A978_9FIRM DNA gyrase subunit A OS=Firmicutes bacterium CAG:102 GN=gyrA PE=3 SV=1
VEDLIEEETCVFTLSNLNYVKRTPLDTYKSQNRGGRGIIGMQT-EEDFVKDLFLASTHDTLLFFTSRGKVYRMKGYEIPEG-RTARGVAIVNLLEIDADE
KIMAVIPAN---EDQYLVMVTKQGLIKKTDMTSFAN-RKSGLIALNLREEDDLISVM-TDG-DEIFVATRSGMGIKFSE--VRPMGRTATGVKAITLK--
-DVVSAVKID--GQLLNVTENGYGKRTTTDKFNLQHRGGKGLKVHQLT-E-TGQLTGVLMVGN-DELMLITSEGVIIRLRGREISSYNRDSQGVKLMNLD
DGSVVGIAKIS-
>tr|A0A0D1X9Y0|A0A0D1X9Y0_ANEMI DNA gyrase subunit A OS=Aneurinibacillus migulanus GN=gyrA PE=3 SV=1
DEDLIPQEEVVISLTHRGYIKRLPVDTYRAQKRGGRGIQGMGA-EDDFAQHLITTNSHHYLLFFTNKGKVYRLKAYEIPEG-RTAKGIPIINLLQIEQ-E
YIQTVIPIK--TDNHYLFFATKQGIVKRSDLTSFSN-RRIGLFAINLREDDELISVR-TDG-QNIIIGTEKGMSILFSE--VRIMGRSATGVKGIHLS--
-DVIDMDIAEA-ADVLIVTSFGYGKRTPLSSYRFQTRGGKGIKTLHLT-E-NGVIVGLKVV-E-NDLMLVTSAGIIIRLCVNDISSMGRNTQGVKLIRLG
QE-VATVAKVE-
>tr|A0A0F6CLJ5|A0A0F6CLJ5_MYCGL DNA gyrase subunit A OS=Mycoplasma gallisepticum S6 GN=gyrA PE=3 SV=1
NEQLIPVETVVITRSSKGYLKRIPISAYKVQHRGGVGVKGMNT-EDDDVESLIVCSTHSDLLFFTNYGKVYRIRAHQVPLS-RISKGIPAINLISIEKDE
KLMSLLSIN---DSGYFFFSTRKGLVKRVKASEFSRIQNNGKIAIKLTENDSLFKVIKTAGDEEIYIGVSSGLLVRFK---VRSMGRTAQGVIGVKFR--
-EVIGLSSS--GSLLLAVCEKGVGKMTDREEYRMTNRGSKGVITIKVTP-KTGNIINTQLVN-NEELLMISSTGKIVRVPLAEVSE-GRNTSGVKLISLN
-KTLQSVAIFD-
>tr|S0K5J9|S0K5J9_9ENTE DNA gyrase subunit A OS=Enterococcus dispar ATCC 51266 GN=gyrA PE=3 SV=1
DEDLIEEEEVVITLTNNGYIKRLANSEFRAQRRGGRGVQGMGV-DEDFVKTLVSCSTHDTLLFFTNVGKVYKAKGYEIPEYGRTAKGIPVINLLGI-DAE
KIQTIIAVS--SDNKYLFFTTLLGVVKRTSVDAFSN-RSNGLIAINLKENDELVDVL-TSG-DTMIIGTHDGYSVTFKE--VRDMGRTASGVRGIRLR--
-NVVGVSVITPDKEVLVITENGYGKRTAGLEYPVKGRGGKGIKTANIT-A-NGPLAGLTTVNN-EDIMLVTNKGVIIRFNVASVSQTGRATLGVRLMKLE
D-KVVTMAAVE-
>tr|A0A091BXC6|A0A091BXC6_9ENTE DNA gyrase subunit A OS=Tetragenococcus muriaticus 3MR10-3 GN=gyrA PE=3 SV=1
DEDLIEEEEIVVTLTNNGYIKRAANSEFRTQNRGGRGVQGMGV-DQDFVTTLVSCSTHDNLLFFTNAGKVYKAKGYEIPEYGRTAKGIPVINFLGI-DNE
RIQTVIALS--QERKYLFFTTKYGIVKRTSVEAFKN-RSNGLIAIGLKDQDELVNVL-TCG-DVMIIGTHKGYSVTFQE--VRDMGRTASGVRGIRLR--
-EVVGAAVIRENDEVLVITEKGYGKRTAGDHYPVKGRGGKGVKTANIT-E-NGPLAGLTTVSN-EDVMVITDKGVIIRFRVEDISQTGRSTLGVRLMKME
D-KVVTMATVD-
>tr|K8ZKS6|K8ZKS6_9ENTE DNA gyrase subunit A OS=Catellicoccus marimammalium M35/04/3 GN=gyrA PE=3 SV=1
DEDLIEQEDIVITLTNNGYIKRLANTEFRTQRRGGRGVQGMSM-QDDDMQTILTCSTHDLLLFFTNKGKVFKAKGYEIPEYSRNAKGIPVINLLGL-EEE
SIQSIIKVD---PKQELFFVTKNGLVKRTAFAAFAN-RSNGLKAIQLKDEDELIQVM-TSG-DQIMIATHEGYSINFME--VRSMGRTAAGVRGIRLR--
-GVIGATTVSPEAQILVVTENGYGKRTEVSAYPVKKRGGKGVKTLQKT-E-TGGLVALCTVTT-DDVLVMTNRGVMIRFAVDTISTIGRVAQGVRIIRLE
G-TVSTVDIIE-
>tr|K1MKP7|K1MKP7_9LACT DNA gyrase subunit A OS=Facklamia ignava CCUG 37419 GN=gyrA PE=3 SV=1
DEDLIPESKVLIALTNNGYVKRMDQDEFQVQRRGGRGVRGMGL-EDDNIQTLISCSTHDTLLYFTNTGRVFRTKGYDVPEYGRQARGLPIVNFLSL-DGE
SIKEVIAIEE-VSDGYLFFVTQSGTVKKSNISDYFN-RQNGLIALNLKEDDEVVNVF-TDG-QAIIIGTRHGYAMAFHE--VRPMGRTATGVRGIRLR--
-DVVAADVFNAGEEILVVTENGYGKRTAVEEYSLKNRGGLGVQTVRLS-E-SGYLTGLVSTDS-EDIMIMTDTGVVIRFDINDISQTSRVTLGVRMIRLD
G-KVSSLTAIS-
>tr|E6LEK2|E6LEK2_9ENTE DNA gyrase subunit A OS=Enterococcus italicus DSM 15952 GN=gyrA PE=3 SV=1
DEDLIEEEEIVITLTNNGYIKRVANTEFRAQRRGGRGVQGMGV-DEDFVKTLVSCSTHDTLLFFTNAGKVYKAKGYEIPEYGRTAKGIPVINLLGI-DSE
RIQAIIAVK--AAEQYLFFTTKLGVVKRTDVQAFSN-RSNGLIAIGLKEQDELVNVL-TKG-DTIIIGTHGGYSVTFAE--VRDMGRAAAGVRGIRLR--
-GVVGTAILTPESEVLVITENGYGKRTASSEYPVKGRGGKGIKTANIT-P-NGPLAGLTTVSE-EDILVITDKGVIIRFNVATVSQTGRATLGVRLMKME
E-KVVTMATVE-
>tr|C9CLY6|C9CLY6_ENTCA DNA gyrase subunit A OS=Enterococcus casseliflavus EC10 GN=gyrA PE=3 SV=1
DEDLIEEEEIVITLTNNGYIKRVAKSEFRAQRRGGRGVQGMGI-DEDFVKTLVSCSTHDTLLFFTNKGKVYKAKGYEIPEYGRAAKGIPVINLLGI-DSE
RIEAIISAS--QEGRYLFFTTRLGVVKRTSVTAFSN-RANGLIAIGLRENDELVNVI-THG-DVVIIGTHDGYSVTFKE--VRDMGRTAAGVRGIRLR--
-GVVGAAVITEDSEVLVITENGYGKRTKGSEYPIKGRGGKGIKTANIT-A-NGPLAGLTTVSE-EDIMVITDKGVLIRFNVATVSQTGRATLGVRLMKME
N-KVVTMATVE-
>tr|R2SGE5|R2SGE5_9ENTE DNA gyrase subunit A OS=Enterococcus asini ATCC 700915 GN=gyrA PE=3 SV=1
DEDLIEEDEVVITLTNNGYIKRVSNSEFRAQRRGGRGVQGMGV-DEDFVKTLVSCSTHDTLLFFTNMGKVFKAKGYEIPEYGRAAKGIPVINLLGI-DNE
QIQTIIAVN--TSGRFLFFCTRLGIVKRTSVEAFAN-RSNGLIAIGLKDGDELVSVL-TDG-SNIIIGTHTGYSVTFAE--VRDMGRTAAGVRGIRLR--
-EVVGVAPITPEKEVLVVTENGYGKRTSGSEYPVKGRGGKGIKTANIT-A-NGPLAGLTTVDD-EDIMVITDKGVIIRFNVGDVSQTGRATLGVRLMRME
E-KVMTMAVIE-
>tr|A0A0P8BVZ2|A0A0P8BVZ2_9CYAN DNA gyrase subunit A OS=Phormidium sp. OSCR GN=gyrA-2 PE=4 SV=1
LDLEPQAEETVLEITQRGYGRRLPPKNVTPIEPQ-----E----ED-FPLQQVV-QTDRPLLMFVRDGKVYSAAVGDIAKN-GRNRGQPLVGLLPPAP-E
-AIAQFVAD--LEQQQVVFLTQGGRIKRLAVSEIGQ-T-RGLTVLKFK--DGLYG---R----DAIVASSGGRLL------LPLLGRTAQGYQ-VRLR--
-TIAGLGIVEP--ELVLVTERGYCKRLPV-ELR-GERGAIGTQGL--AKS---DL-TIVRAVE---LLLHLNGDRLLRVPI-SLKR-GK---GQRPKLLK
K-SVISTRLCL-
>tr|K7WBX3|K7WBX3_9NOST DNA topoisomerase (ATP-hydrolyzing) OS=Anabaena sp. 90 GN=gyrA PE=4 SV=1
K-PEAPLEETIVEVTQRGYIRRIS---------PN-K--TGEN-HD-FLIQTALTNTHKDLLILTSGGKVYPITVGDIPLT-GRSRGTPLITMLTSTT--
---TRFLLP--E-TLEMVLLTKEGRIKRLSLSEFVN-S-RGITILKLK--DELAF---S----HLILASSSGRLL------LPIMGRAAMGLQAFRLL--
-NMVGCVNVS-NHQLLLVTEEGYGKIMPA-QLR-ASRGDLGVQLV--NKT---DL-AMVAAK-GSEVALLTNKERVIRVSV-AVPN-NK---GESICQLN
D-RIISVVEVE-
>tr|Q3M969|Q3M969_ANAVT DNA topoisomerase (ATP-hydrolyzing) OS=Anabaena variabilis (strain ATCC 29413 / PCC 7937) GN=Ava_2854 PE=4 SV=1
S-PLEPAEEAILEITHRGYLRRIQ----------P-K--SVEN-HD-FIIQTNITDTHKELLVLTNGGKLYPVKVGDIPLT-GRSRGTPLITMLTTTQ--
---SRLLLP--A-AQQLILLTKQGRIKRLSLEELTN-T-RGVTILKLK--DELLL---K----HLILASSGGRLL------LPIMGRTAMGLQAFRLL--
-NMVGCVNAA-AEYLLLVTEEGYAKRLPV-QIK-ANRGDLGTQSM--VKT---DL-AMVGAN-SSEVALLTNRERVVRIST-TVPI-PR---GETILQLN
D-KVIAVVEVR-
>tr|A0A0R0M761|A0A0R0M761_9NOST DNA topoisomerase IV OS=Cylindrospermopsis sp. CR12 GN=ASL19_04435 PE=4 SV=1
Q-EEQPPEPAILEFTHRGYVRSLA---------PG-K--AAET-ND-FLIQTEITNTHQDLLILNTSGKVYPAKVGDISPS-PRSRGIPLITLLTNTV--
---GRFILP--D-THDMVIVTKQGRIKRLSLEELTN-S-RGITILKVK--DQLCF---N----NLILASSGGRCL------LPVMGRGAMGLQSFRIL--
-SIIGCVAIG-EENLLLVTQEGYAKKISS-SLR-GNRGDLGTQML--HKT---DL-AITRTN-SQEVALVTNKDRVIKTSI-SIPI-DR---GENILPMT
D-IITSVVLVL-
>tr|K9ZG34|K9ZG34_ANACC DNA topoisomerase (ATP-hydrolyzing) OS=Anabaena cylindrica (strain ATCC 27899 / PCC 7122) GN=Anacy_2720 PE=4 SV=1
K-SEQPAEPAILEFTQRGYVRRLS---------ST-K--PAEN-HD-FIIQTESTDTEKDLLILNTGGKVYPVKVGEIPAT-GRSRGTPLITMLTSTL--
---SRFVLP--D-TTQIVLLTKQGRIKRLSMEEFTN-G-RGITILKLK--DELSF---T----HLILASSGGRLL------LPVMGRAAMGLQAFRLV--
-NMVGCVTVS-DDHLFLVTEEGYAKRMPA-NLR-ANRGDLGIQML--HKT---DL-GMVRAT-GVEVALVTNRERVVRISI-TVPI-DR---GESILQLN
D-KIITLVGVG-
>tr|K9R820|K9R820_9CYAN DNA topoisomerase (ATP-hydrolyzing) OS=Rivularia sp. PCC 7116 GN=Riv7116_1017 PE=4 SV=1
A-IQAPVEDVILDFSQRGYVRRIN---------SS-K--SSDS-YD-FILQAHETNTQKDLLVVTSGGKAYPLQIGEIPAA-RG-RGTPLITLLTSTG--
---SRLVIP--Q-KAYVILLTKQGRIKRLSAEELTN-T-RGVSILKLK--DELLL---T----HLILASSGGRVL------LPCMGRTAVGLQALRVG--
-QIVGCTRFN-NNNLLLVTQEGYAKQLSA-KLK-ANRGDLGAQAF--APT---DL-GIGLVK-ETQIALVTSNQRVIRLDG-SVPL-TK---GEKVVELN
D-KIVSVHEIN-
>tr|K9PJ62|K9PJ62_9CYAN DNA topoisomerase (ATP-hydrolyzing) OS=Calothrix sp. PCC 7507 GN=Cal7507_2776 PE=4 SV=1
K-SSEPPEETVLEFTQRGYVRRSL---------PN-K--PADN-HD-FLIQTELTDTEKDLLILTSGGKVYPVKVGDIPAT-GRSRRTPLITMLTNTQ--
---SRFLLP--P-TTQMILLTKQGRIKRLSLEEFTN-T-RGVTIVKLK--DELLF---N----HLIVASSGGRLL------LPAMGRTAMGLQALRLR--
-YMVGCVTVS-DDQLLLVTQEGYAKRIPA-SLR-ANRGDLGTQAL--TKT---DL-AMVIAMYSAEVALVTNKERVVRIPV-TVPL-NR---GESILQLN
D-KIMTVAPVR-
>tr|Q1LT83|Q1LT83_BAUCH DNA gyrase subunit A OS=Baumannia cicadellinicola subsp. Homalodisca coagulata GN=gyrA PE=3 SV=1
IEDMINKENVVVTLSYQGYVKYQPLNDYDAQKRGGKGSAVK-MKEEDFIHSLLVANTHDTILLFSSRGRMYWMKVYQLPAASRGSRGRPIVNLLPLE-NE
RITTILPVRQYEEGCNVFMATASGTVKKTALIAFSRPRSAGIIAVNLHEGDELIGVNVTNGNNEVMLFSAYGKVVRFPETQVRSMGRTATGVRGINLA--
EGVVSLIIPNI-GHILTVTQHGYGKRTTQNEYPTKSRATQGVISIKASE-RNGQVIGAIQVDEHDQIMLITDAGTLVRTRVSEVSIVGRNTQGITLIRTA
ENHVVGLQRIA-
>tr|A0A0Q6JYL3|A0A0Q6JYL3_9NOCA DNA gyrase subunit A OS=Rhodococcus sp. Leaf258 GN=ASH03_00430 PE=4 SV=1
DEDLIARENVVVTITETGYAKRTRTDLYRSQKRGGKGVQGA-GKQDDIVSKFFVCSTHDWILFFTTKGRVYRAKAYELPEANRTARGQHVANLLAFQPDE
RIAQIIQIK---AP-YLVLATKAGLVKKSKLADFDS-RSGGIVAVNLRG-DELVGAV--TNSDDLLLVSAQGQSIRFSE--LRPMGRATSGVQGMRFN-E
-DLLSLNVVKDGTYLLVATSGGYAKRTAMEDYPPQGRGGKGVLTIQYD-PRRGTLVGALIVED-DELYAITSSGGVIRTAARQVRK-GRQTKGVRLMNLG
-GNLLAIARNA-
>tr|A0A0R2B9Y9|A0A0R2B9Y9_9LACO DNA gyrase subunit A OS=Lactobacillus murinus DSM 20452 = NBRC 14221 GN=FC48_GL002023 PE=4 SV=1
DEDLIEEENVVITLTHNGYIKRLPTSDFKAQRRGGRGVQGMGV-DDDFIEHLITTSTHDELLFFTNVGKVYRMKGYEVPEYGRAAKGIPVINLLDL-DEE
KIQTVINVE--DDSHFLFFTTVKGTVKRTSVTEFGN-RKNGLKAISLHDGDELIHVS-TDG-QNIIIATHGGYAVSFAE--VRPMGRSAAGVRGIRLR--
-EVIGASILRPDSKVFVISEKGYGKQTPASEYPIKGRGGKGIKTTNIT-A-NGNLAGMTTVND-EDIMVITDKGVMIRFNLANVSQTGRATLGVKLINLD
D-TVSTMAKVE-
>tr|F7R1K9|F7R1K9_9LACO DNA gyrase subunit A OS=Lactobacillus ruminis SPM0211 GN=gyrA PE=3 SV=1
DEDLIEEENVVIALTHNGYIKRLPTSDFKAQRRGGRGVQGMGV-DDDFIEHLITTSTHDEVLFFTNIGKVYRMKGYEVPEYGRAAKGIPVINLLDL-SGE
KIQTVINVD--NDSHFLFFTTVQGVVKRTSVTEFGN-RKNGLKAITLREGDELLNVS-TDG-QNIIIGTHGGYAVSFSE--VRQMGRAASGVRGIRLR--
-DAVGSDVLKPDSNVFVISEKGYGKQTPASDYPIKGRGGKGIKTSNIT-E-NGSLAGLTIVDT-EDIMVITDKGVMIRFNVKSVSTTGRSTMGVHLINLD
D-KVSTIAKVE-
>tr|A0A0C1V580|A0A0C1V580_9CYAN DNA topoisomerase (ATP-hydrolyzing) OS=Lyngbya confervoides BDU141951 GN=QQ91_19895 PE=4 SV=1
ILAEHKEEDVVLEFSQKGYVRRSTTRAYQRRQARQN---R-EF-ED-PTLQTEAANTAEELLVLTRDGKAFTLTVGEIPQS-RQSKGVPLVNLL-PSP-E
A--THLVLT--ALTHDLVLLTRLGKIKRVPLSDFQN-T-RGLTAVKLK--DELAF---Q---EELAIATSGGRLI------LPVMGRTAQGPQALRLRK-
-QIVGCVRIQ-DDCVLMVSAAGFAKRLPI-GIH-GARGGIGTQAF---KQK-TDL-AIAPSP-NGEMTVVTSQTRCAQIPI-TIPR-GR---NYRLSKFA
G-RIETVTLTA-
>tr|Q8DIH1|Q8DIH1_THEEB DNA topoisomerase (ATP-hydrolyzing) OS=Thermosynechococcus elongatus (strain BP-1) GN=gyrA PE=4 SV=1
---DCGGDSLWLEMSYRG------------DLP-----------EP-L-PLGFSAQTSDRLWVFTESGKVYPLSVERLPVS-HRERDQPLLTLLPEST--
---SV--IP--ATADKLILLTRQGRIKVIPSSSLQN-R-RGLQLTKLK--DTLGW--------HLVLATSRGRVF------IPVLGRLHQGQAAVRLS--
-QLVGAIALS-HENVILVTASGLGKQVPL-LIE-VPLGHLGQLAI--GKL---DL-GIGRGS--RPLALVTTQERAWITHG-EIPI-NR---GGAIAPLD
G-QVQAVVALA-
>tr|B4WQS4|B4WQS4_9SYNE DNA topoisomerase (ATP-hydrolyzing) OS=Synechococcus sp. PCC 7335 GN=S7335_1886 PE=4 SV=1
A-AEESEEEFILEFTRKGYVRRASPKTRTRRK-DA-G--T--A-DD-VTIQTEITNPTEEVLVLTQEGKAFTLSVSDVPIQ-R-QKGVPLIGLLPDAP--
---TQIVLS--L-AQQLILVTAKGRVKRLPASEMSN-T-RGLTAVKLK--DLLKH---P----DLVLASSGGRVL------LPEMSRTAQGPQGIRLP--
-SLVGCIPVS-KDTLILVSNKGYGKRILV-TFK-SNRGGIGSQSF--NKS---DL-SLNVAV-EANLTVLTDQGRAAKIAI-SVPL-GR---CARLVTPE
T-TIVETLVTD-
>tr|V5V3U1|V5V3U1_9CHRO DNA topoisomerase (ATP-hydrolyzing) OS=Thermosynechococcus sp. NK55a GN=gyrA-2 PE=4 SV=1
---DCGGDSLWIEISCRGYGRCLPQQRRRSGLP-----------EP-L-PLGFSVQASDRLWVFTESGKVYPLPVERLPVS-RRERGQPLLTLLAESS--
---TV--IP--ATAEKLILLTRQGRIKVIPISDLQD-R-RGLQLTKLK--DALGW--------HLVLATSRGRVF------IPALGRLNQGQAAVRLS--
-QLVGAIALS-RENVILVTASGLGKQVPL-LIE-VPLGHLGQLAM--QKS---DL-GIGPGR--SSLALVTTQERAWITNG-EIPL-NK---GVAIAPLD
G-QVQAVVALA-
>tr|U9VKP8|U9VKP8_9CYAN DNA topoisomerase (ATP-hydrolyzing) OS=Leptolyngbya sp. Heron Island J GN=N836_25005 PE=4 SV=1
E-AEAQEEETVVEFTRKGYARRLSPRTYQRRQGKQ-K--P--K-DD-VTTQTEFAWTTHNLLVFSRDGKAYSLSVNDVPLQ-R-QKGQPLVNLLPDAP--
---PPILLT--M-ERQVILVTAQGKIKRLPLTEFES-T-RGLVAIKIK--DHLAY---E----DLMLASSSGRLL------LPDTSRNSQGTQAIRVI--
-GVVGCLPIQ-NSKMLLMSIKGYAKRMQV-AIN-SSRGGIGSQSF--STG---DL-TLVKVP-TADFTVLTSQDRAARLRI-RVAL-GR---CDRIFTPA
G-TITDILVSV-
>tr|K9EXM7|K9EXM7_9CYAN DNA topoisomerase (ATP-hydrolyzing) OS=Leptolyngbya sp. PCC 7375 GN=Lepto7375DRAFT_2818 PE=4 SV=1
V-AEAQEEETVVELTRKGYVRRLSPRTYQRRQGKQ-D--P--K-DD-VTTQTEFAWTTHNLLIFSRDGKAFSLAVGDIPLQ-RQQKGQPLVNLLPDAP--
---PPILMT--M-TQQIILVTAQGKIKRLPLTEFES-T-RGLVAIKLK--DHLAH---D----DLMLASSGGRLL------LPDTSRNAQGTQAIRVL--
-GVVGCVPIQ-KSKLLLMSTKGYAKRMQV-AIK-SSRGGIGSQSF--STG---DL-ISLEAP-SADFIVMTSEERVASLAA-RVPL-GR---CDRMFTPA
G-LITDILVSV-
>tr|A0A0P8BRW1|A0A0P8BRW1_9CYAN DNA gyrase, A subunit OS=Phormidesmis priestleyi Ana GN=gyrA PE=4 SV=1
V-AEENEVEFVLEITRKGYIRRSAVKAYSRRKAKE-Q--T--Q-DD-VTIQAEITNPNQEILVLTKDGKAYSVNTNNVPMQ-R-QKGVPLINLLPPAP--
---THIVLT--L-AQQLIVVSSQGRIKRLPAAELTN-S-RGLTVLKIK--DTLLF---D----DLVLASSGGRLL------LPEMSRASQGTKGIRLT--
-TLVGCVPVR-SDSLLLISEKGYGKRMLV-NFK-SNRGGIGSQSF--SKS---DL-ALLTAE-ESTFTILTDENRFAKMAV-KVPL-GR---CARLFTPG
S-TVIEARITD-
>tr|K2BPT7|K2BPT7_9BACT DNA gyrase subunit A OS=uncultured bacterium (gcode 4) GN=gyrA PE=3 SV=1
IEDLIPDEEVVVTLSHEGYVKTQLLSVYQAQHRGGRGTATT-MKEEDYVEFLIAARTHDTILCFTTQGKVYWLKVYQFPQANRTSRGKPIINLLPLA-GE
RVNAFLPVREYLENQYVVFATSKGLIKKVSLVDFSRPRSSGIIAIALNEGDYLVQADITDGEHDIMLFTDAGKVVRFPESKVRCMGRQAAGVRGVKLQD-
-QVVSLVVAR-DGAILTATENGYGKRTAIDEYRLSGRGGQGVISIHVNE-RNGKVVGAIQVNEEDEVMLISNKGTLVRVPAAEISLIGRNTQGVRLIQLS
EGSLVSLERII-
>tr|K1ZGU4|K1ZGU4_9BACT DNA gyrase subunit A OS=uncultured bacterium (gcode 4) GN=gyrA PE=3 SV=1
LEDLLPEEDVVVTLSHEGYAKSQPVALYQAQHRGGKGSATN-VKEEDFIERVLVANSHDTILCFSNHGKVYWLKVYQLPQASRNSRGKPIVNLLPLA-GE
KINAILPVRDYRKDQFVFMATAKGTVKKVALTEFSRPRSNGIIALELADNDKLIGVDITNGQQEVMLFTNAGKVILFSEEDVRSMGRTARGVRGVKLQKQ
Y-VISLIVVH--GDILTATKNGYGKRTAIEEYRSTGRGGQGVISIQVTE-RNGDVIAATQVNPVDEVMLISNKGTLVRVPVAEISLVGRNTQGVRLINLV
NDLLVGLERIA-
>tr|R7F263|R7F263_9BACI DNA gyrase subunit A OS=Bacillus sp. CAG:988 GN=gyrA PE=3 SV=1
DESLIPVEKSIITLTNNGYIKRMPVDTYRSQNRGGVGIKGMST-ENDFVSQLVSVSTHDSVLFFTNRGKVYRMKGYEVPAS-RQSKGLPIINLLPLEKEE
SVNSIIALNE--DSDYLTFITKEGLVKRTNVLEFKKIRNSGKLAIILHDDDELVAVRKTKGNNEIVIGASNGRMVRFD---VRSMGRGTSGVKGIDL---
-YVVGAEII--NAEILIVTEKGYGKRTNIDEYRLTHRGSKGVKALNVTE-KNGAMIALKTVS-DEDLIIITDSGVLMRMSLEQVST-KRATQGVRLINLK
-NKVATVALVE-
>tr|A0A0G0PAP7|A0A0G0PAP7_9BACT DNA gyrase subunit A OS=Microgenomates (Levybacteria) bacterium GW2011_GWB1_39_7 GN=gyrA PE=3 SV=1
EEDLIQNEPTVITITKTGYIKRQGMTSFKTQARGG-G--RMT--ED-VIDQILYAETHDFILFFTNLGKVYQTRVFEMAES-RVSKGTAIVNLI-DTG-E
T--SILTYS--ADFKHIVMATEKGVVKKTALSEFTN-R-GGIIAIKLE--DSLQW---SD---DLVLITKKGKII------VRSTGRSSQGVRGIKLIG-
-DLIGMDVVSGTATLLIVAQNGLGKRTRV-EVR-QRRGGQGVRVA---NNKTGDV-SAGVLD-ATEVIITSLKGQVVKIPL-STPL-SR---GVILMRFS
K-KVASATTIS-
>tr|K9YDW2|K9YDW2_HALP7 DNA gyrase subunit A OS=Halothece sp. (strain PCC 7418) GN=gyrA PE=3 SV=1
DLDLIANEQAIILVTEQGYIKRMPVNTFGSQNRATRGKSATKM-EDDEIEHFISCCDHDHLLFFSDRGVVYALSAYQVPIGSRTARGTPLLQMLPISQEE
KITTVLAVR---EEDYLIMLTRQGNIKKTSLSAFSNIRTNGLIAISLADEDQLRWVRLAKESDSIIIGSRKGMAIHFRA--LRPLGRATRGVKAMKLK--
-DLISMDILPATLWILAITKGGYGKRVPITQFRLQNRAGKGLSAMKF----QDCLAALKVVH-GEELMLVTNRGIIIRQGSDAIPRQSRQATGVRVQRLD
-DAIAAVALVP-
>tr|A0A075JJ18|A0A075JJ18_9BACI DNA gyrase subunit A OS=Virgibacillus sp. SK37 GN=gyrA PE=3 SV=1
DEDLIPEENIVITLTHQGYIKRLPSSTYRTQKRGGRGIQGMGT-EDDFVEHLVSTSTHDTVLFFTNKGKVYKAKGYEVPEFSRTAKGIPIINMLQVEK-E
WVNAVISVN---DDNYLFFTTKHGISKRTTLTQFAN-RKGGLIAVGLRDEDELISVR-TDG-QDIMIATKNGYLIRFEE--IRSMGRTAAGVKGISLR--
GDVVSMEILQEDSNILHVTNKGYGKQTPENEYRRTNRGGKGVFTCNLT-EKTGLVVAVKAVSD-EDLMMITVAGVLIRIPVKDISETGRNTMGVRLIRLQ
-NEVATVASVD-
>tr|K0IUW9|K0IUW9_AMPXN DNA gyrase subunit A OS=Amphibacillus xylanus (strain ATCC 51415 / DSM 6626 / JCM 7361 / LMG 17667 / NBRC 15112 / Ep01) GN=gyrA
DEDLIPEEDIVVCLTHRGYIKRLPSSTYRTQNRGGRGVQGMST-DDDFVEHLVTASTHDTILFFTNKGKVYRLKGYQIPEYGRAAKGLPVINILEIEK-E
WVNTVISAP---EDKFLFFTTKHGISKRTSLNQFAN-RRNGIIALTLRDEDELISVQ-TDG-KDIMIATRNGYLIRFDE--IRSMGRSAAGVKGISLR--
DDVVSMEIVEENDYILNVTENGYGKRTPESDYRMINRGGKGVFTANVT-DKTGSVVAVKSVND-EDLMIMTDSGVLIRTPIEAISITGRNTQGVRLIRLQ
-DKVATVACVE-
>tr|A0A0P7J7X9|A0A0P7J7X9_9BACI DNA gyrase subunit A OS=Lentibacillus amyloliquefaciens GN=AOX59_11620 PE=4 SV=1
DEDLIPEENVVITLTHQGYVKRLPASTYRTQKRGGRGIQGMET-EDDFVEHLVSTSTHDTILFFTNKGKVYRAKGYEVPEFSRTAKGIPIINLLQVEK-E
WINAVISVA---EDYFLFFTTRYGLSKRTKLSQFAN-RKGGLIAVGLRDEDELISVR-TDA-KDIMMGTKNGYLIRFPE--VRSMGRNAAGVRGISLR--
DDVVSMEILDKGVEVLHVTNKGIGKRTPEEQYRITNRGGKGIFTCKLA-DDN-EVVAVKAVTD-EEIMLITVAGVLIRIPVEGISQTGRNAQGVRLIRLN
-NEVATVAKVD-
>tr|A0A0A1MBA6|A0A0A1MBA6_9BACI DNA gyrase subunit A OS=Oceanobacillus oncorhynchi GN=gyrA PE=3 SV=1
DEDLIPEENIVITLTHQGYIKRLPASTYRTQRRGGRGIQGMGT-EDDFVEHLVSTSTHDTVLFFTNKGKVYKTKGYEVPEFSRTAKGIPIINLLQVEK-E
WVNAVISVT---EDHFLFFTTKLGVAKRTSLEKFKN-RKGGLIAVNLREEDELISVR-TDG-KEIMIATKNGYLIRFEE--MRPMGRTAAGVKGISLR--
DDVVSMEIMDEGSKILHVTSKGFGKQTPEDEYRRINRGGKGVFTCKLD-EKTGHVVDVKAIQD-EDLMVITAGGVLIRMQVSDISQTGRNTKGVHLIRLQ
-DEVATVARIE-
>tr|Q8EU82|Q8EU82_OCEIH DNA gyrase subunit A OS=Oceanobacillus iheyensis (strain DSM 14371 / JCM 11309 / KCTC 3954 / HTE831) GN=gyrA PE=3 SV=1
DEDLIPEENIVITLTHQGYIKRLPASTYRTQKRGGRGIQGMGT-EDDFVEHLVSTSTHDTILFFTNKGKVYKAKGYEIPEFSRTAKGIPIINLLQVEK-E
WVNAVISVN---EEAYLFFTTKHGIAKRTSLEKFRN-RKGGLIAVGLREEDELISVR-TDG-KEMMIATKNGYLIRFEE--IRSMGRTAAGVKGISLR--
DDVVSMEIIEPGSKILHVTNKGFGKQTDESEYRRINRGGKGVFTCKLD-EKTGNVVAVKAVND-EDLMLITIAGVLIRIQVQDISQTGRNTKGVHLIRLQ
-GEVATVTRIE-
>tr|A0A0K0G6D7|A0A0K0G6D7_9FIRM DNA gyrase subunit A OS=Bacilli bacterium VT-13-104 GN=gyrA PE=3 SV=1
DEDLIPEENIVITLTHKGYIKRLPSSTYRTQKRGGRGIQGMGT-EDDFVEHLVSTSTHDTILFFTNKGKVYRAKGYEVPEFSRTAKGIPIINMLQVES-E
WVNAVISVS---EEAYLFFTTKFGITKRTSLSMFAN-RKGGLIALGLREDDELISVK-TNG-KDIMIATKQGYLIRFEE--IRAMGRTAAGVRGISLR--
DDVVSMEVLEEGSHILHVTNKGYGKQTPESEYRRINRGGKGVITCKLN-DKTGHVSAVKAVNE-EDLMVITVGGVLIRIPVKDISITGRSTMGVRLIRLH
-DEVATVAKIE-
>tr|A0A024Q7D7|A0A024Q7D7_9BACI DNA gyrase subunit A OS=Virgibacillus sp. Vm-5 GN=gyrA PE=3 SV=1
DEDLIPQENIVITLTHQGYIKRLPSSTYRTQKRGGRGIQGMGT-EDDFVEHLVSTSTHDTVLFFTNKGKVYKAKGYEVPEFNRTAKGIPIINLLQIEK-E
WVNAVISVK---EDHFLFFTTKYGISKRTSLAQFAN-RKGGLIAVGLREEDELISVR-TDG-KDMMIATKNGYLIRFPE--IRSMGRTAAGVKGISLR--
DDVVSMEIVQKDAKILHVTSKGYGKQTPESEYRVTNRGGKGIFTCNLT-DKTGHVTAVKAVSE-EDLMVITVDGVLIRIPVVDISETGRNTMGVRLIRLR
-DAVATVTRID-
>tr|F6ERE6|F6ERE6_AMYSD DNA gyrase subunit A OS=Amycolicicoccus subflavus (strain DSM 45089 / DQS3-9A1) GN=gyrA PE=3 SV=1
DEDLIAREDVVVTITETGYAKRTKTDLYRAQRRGGKGVQGA-GKQDDMVRHFFVTSTHDWILFFTTKGRVYRVKAYELPEMSRTARGQHVANLLAFQPGE
KIAQIIAIK---AP-YLVLATRNGLVKKSRLEDFDS-RSGGIVAINLRE-DELVGAV--SSDDDLILVSGKGQAIRFAE--LRPMGRATSGVQGMRFN-D
-DLLSLNVVQETMFLLVATSGGYAKRTPLDEYPVQNRGGKGVLTIQFD-ARRGTLVGAIIVDK-DELYAITSGGGIIRTAASQVRK-GRQTKGVRLMNLG
-GNLLAIARNA-
>tr|A0A0M9UFF9|A0A0M9UFF9_9BACT DNA gyrase subunit A OS=Candidatus Symbiothrix dinenymphae GN=gyrA PE=3 SV=1
PEDFYADDEMIITISHLGYIKRTPLGEFKSQHRGGVGVKGAES-DEDFVEYIYPANMHATMLFFTQKGRCFWMKVYQIPEGTKTSKGRAIQNLLSIDADD
SVSAFVRVKN--ASNYLIFCTKKGIIKKTSLEAYSR-RQNGVNAISLREGDELINVRLTNGTNDIIIANRKGLAIRFN---VRRMGRNAAGVRGQKLS--
-DIVGMIVIKNDDHILVVSEKGYGKRSDL-EYRVTNRGGKGVKAMKITG-KTGPLVTIKTVT-DNDLMIINKSGMTIRLKIANLNIIGRATQGVRLINLD
RNEIASVCVVA-
>tr|B6YS22|B6YS22_AZOPC DNA gyrase subunit A OS=Azobacteroides pseudotrichonymphae genomovar. CFP2 GN=gyrA PE=3 SV=1
SDDFYADDEMIITISHLGYIKRTPLVDFRAQNRGGVGTKSSEI-DKDFVEYIYAANMHAMMLFFTRKGRCYWLKVYQIPAGAKTSKGRAIQNLLNIDTND
KVSAFIRVKS--ESHYLVFCTKRGIIKKTLLNAYSR-RQNGVKAITVHDGDEVIAVKMTNGNNEIIVANRKGRALRFN---VRSMGRLAAGVISMTLDV-
-DIIGMIIINDRENVLVVSEQGYGKRSRVGDYRIVNRGGKGIKTLNITE-KTGFLVSIKNVT-HNDVMIINKSGIAIRIKVSDLNVIGRATQGVRLINLE
RGEIASVCKVM-
>tr|C7LWV9|C7LWV9_DESBD DNA gyrase subunit A OS=Desulfomicrobium baculatum (strain DSM 4028 / VKM B-1378) GN=gyrA PE=3 SV=1
IEDIIPDEPVVITLSRNGYLKRTSLDNYRQQRRGGTGITGVQV-EEDFITFILTTSNHQYMNLFSNKGKMYQVKVHQIPEGGRTARGKHVANLL-PDSNE
YIAAAMTCR---QEKFYFFYTKLGVVKRSSVHLYRNIRAVGLIALGMRDDDELIGVR-VETNDEMVLVTVDGYSIRFAC--VRAMGRTATGVKGLALR--
-DVVAGVVVNKQQELLTIAENGYGKRTQVEHFRAQSRGGKGIINM--TK--TGKVVGAMMVYPTDELILLTSGSKIIRIGISDISLVGRATQGVRLVRLE
-ETVVCFDHVP-
>tr|C8X5Q8|C8X5Q8_DESRD DNA gyrase subunit A OS=Desulfohalobium retbaense (strain DSM 5692) GN=gyrA PE=3 SV=1
IEDLIPDEEVVITLTRNGYIKRTPLSAYQQQKRGGKGVSGANV-QKDFVTDLMTGTNHQYLLLFTNKGRMHQLKVYQIPEGRRTARGTHIANLL-PDKEE
YVATVLCMK---ANHSFLFATKKGMVKRSAVHLYRNYRPHGLIAVNLRDGDELIAVR-VDEESEIFLITHHGVAIRFAC--VRSMGRGAAGVKGIALR--
-DVVSCVIINGRDQLLTVSEQGYGKRTAIDYYRQQSRGGKGIINM--TK--TGGVLGAMMVDETDELIMLTSMHKMLRIGTADIRICGRATQGVKLVSLD
-ETVVCFDRIV-
>tr|D6SP73|D6SP73_9DELT DNA gyrase subunit A OS=Desulfonatronospira thiodismutans ASO3-1 GN=gyrA PE=3 SV=1
MLDLIPDHDVVVTLSRNGYIKRTLLEYYHQQKRGGKGIAGANV-DKDFITTLFTTSNHKDIYLFSNTGKSYLLKAYEIPEGSRTARGVHIKNLL-PDNEE
YIATALSER---QRHYFLFVTKKGMVKKTSIEMFKNMRSLGLIAVNLKPGDELIGVK-VKDESEVIITTHDGLAIRFAC--LRAMGRNAAGVKGISLR--
-DVVSGAVLDPARELFTISEKGFGKKTSLDMYKLQARGGKGLINM--TK--TGKVVSSMPVSDQEELIIFTSANKIIRLGTSDIRSVGRSTQGVKMVDLE
-DKVICADLII-
>tr|C6BUN7|C6BUN7_DESAD DNA gyrase subunit A OS=Desulfovibrio salexigens (strain ATCC 14822 / DSM 2638 / NCIB 8403 / VKM B-1763) GN=gyrA PE=3 SV=1
IEDLIPDDDAVITLSRRGYIKRTPLSNYQKQKRGGKGIAGVQT-DGDFIHTFLTTSNHQYLLLFTSKGKMFKIKVHQVPEASRIARGAHIANLL-PEKDE
TIATAMTMR---EECFFLFVTKSGMIKRSSIALYRNCRQSGIRAVALKEGDALITVK-VSADSEAVLVTRNGTSIRFSC--ARAMGRVASGVKGIALR--
-DVVSGVVTGDRVQLLTISEGGYGKRTDIDQHRIQTRGGKGIISM--TK--TGKVLGSIMVSPEDEVVLLTSGNKIIRMGVKDVSLVGRATQGVRLVRMD
-GHVVGFDLVQ-
>tr|L0RA54|L0RA54_9DELT DNA gyrase subunit A OS=Desulfovibrio hydrothermalis AM13 = DSM 14728 GN=gyrA PE=3 SV=1
IEDLIPDDDAVITLSRRGYIKRTPLSNYHKQKRGGKGIAGVQT-DGDFIHTFLTTSNHQFLVLFTTKGKMFKIKVHQVPEASRIARGAHIANLL-PEKDE
SIATALTMR---EDRFFLFVTRNGMVKRSSIALYRNCRQSGIRAVSMKEEDQLITVQ-VNIDSEAVLVTKNGTSIRFSC--ARAMGRVASGVKGIALR--
-DVVSGVVTGDRVQLLTVSEGGYGKRTDIEQHRLQTRGGKGIISM--TK--TGKVLGSIMVSVDDEVVLLTSANKIIRLGIKDVSLVGRATQGVRLVRMD
-DQVVGFDLVI-
>tr|A0A0Q3WDP4|A0A0Q3WDP4_BRECH DNA gyrase subunit A OS=Brevibacillus choshinensis GN=AN963_18855 PE=4 SV=1
DADLIPEEDVVITLTHDGYIKRLPVSTYRAQKRGGRGIQGLGT-DDDFVEHLYITNSHDYIMFFTSKGKVYRLKGFEIPDLSRTAKGTPIINLIQIEK-E
RVSAVIPVK---QERFLFFATKKGIIKKTTLESYEN-RKGGLIAVNLRDDDELIGVR-TDG-QEIIMGTKNGMSVRYKE--VRTMGRNATGVKGITLD--
-DVIDMDVIKPNAEVLIVTANGYGKRTPVEEYRIQSRGGKGIKTHNVT-E-SGNVVGLKVVEE-EDLMIITTSGIIIRTEMKGISVMGRYTQGVKLIRLG
N-QVGSVAKCP-
>tr|A0A0F7EFX9|A0A0F7EFX9_BRELA DNA gyrase subunit A OS=Brevibacillus laterosporus GN=gyrA PE=3 SV=1
DADLIPEEEVVISLTHSGYVKRLPVTTYRSQKRGGRGIQGIGT-DDDFVEHLCITNSHDTLLFFTSKGKVYRLRGFEIPDLSRTAKGTPIINLIQIEK-E
TVSAVIPVK---EDQFIFFATKQGIVKKTDLKSFEN-RRGGLFAVNLREDDELINVR-TDG-QQIIMGTRQGMSVRFNE--VRTMGRTATGVKGITLD--
-NVIGMDVIRDDAEVLIVTAKGYGKRTPVSEYRIQTRGGKGIKTHNVT-E-SGQVVGLKVVQD-EDLMIVTITGIIIRMEIKGISVMGRYTQGVKLIRLG
E-EVVSIATVE-
>tr|F5YNX0|F5YNX0_TREPZ DNA gyrase subunit A OS=Treponema primitia (strain ATCC BAA-887 / DSM 12427 / ZAS-2) GN=gyrA_2 PE=3 SV=1
IEDLIKKEEMMILISNLGYVKRVPVTAYKNQGRGGKGMISAKL-EDDFVEQIFVASTHEYIMFITNAGKSYWMKVHELPEGSRTSKGAHIKSLLTISPNE
DITAIVAL----DEQFLFMGTARGVVKKVAASEFSNAKTRGIIAIKLDEGDKLVSALLTGGSDEVVLISRKGQALRTHE--VRAMGRSSRGVTGMKLD--
-ELTGLLRVVEAEKMLILSEYGYGKRVDFSEFSSHGRGTGGQKIY--GD-KTGELVGCVNVLDNEEIMCITSQGKSIKLKVDSIRVMGRSAQGVRILSID
-PFVIGVDRIV-
>tr|F8F3C3|F8F3C3_TRECH DNA gyrase subunit A OS=Treponema caldarium (strain ATCC 51460 / DSM 7334 / H1) GN=gyrA PE=3 SV=1
IEDLIKKEEMVILISNLGYIKRVPVSAYKSQGRGGKGMNSVKL-EDDFVKQLFVASTHDYIMYITSAGKAYWMKVHEIPEGSRTSRGAHIKSLL-ASPNE
DITTVVAFK---EDQFIFMGTARGVVKKVQTVEFANAKTRGIIAINLDEGDSLVSAL-TTGTDEIVLITRKGQALRTEE--VRASGRSSRGVCGIKLD--
-DLAGVLRVNN--KMLILSEFGYGKRVEYSEFSSHGRATGGQRIY--SK--TGELVGCVSVGDEDAIMCITSQGKSIKVAVNEISVMGRSAQGVRIVNIE
-PFVIGVDRIA-
>tr|F5YGG7|F5YGG7_TREAZ DNA gyrase subunit A OS=Treponema azotonutricium (strain ATCC BAA-888 / DSM 13862 / ZAS-9) GN=gyrA_2 PE=3 SV=1
IEDLIKKEEMMITISNLGYVKRVPVSAYKNQGRGGKGMQAAKL-EDDFVEQIFVASTHEYIMFITNEGKAYWMKVHELPEGTRTSKGAHIKSLLTVSPNE
DITAIVSF----DDQYILMGTARGVVKKVKTSEFSNAKTRGIIAIKLDEGDELVSALLTGGKDEVVLISRRGQALRTHE--VRPMGRAGHGVTGMKLA--
-ELTGLLKVSEDEKMLILSEYGFGKRVDFSEFSSHGRGTGGQKIY--GE-KTGEIVGCVGVRDKEEIMCITSQGKSIKLKVASIRVMGRSAQGVKILSID
-PFVSGLDRIV-
>tr|K6H061|K6H061_9GAMM DNA gyrase subunit A OS=SAR86 cluster bacterium SAR86E GN=gyrA PE=3 SV=1
NEDLIPEETRVLTLSRSGYAKTQPLDEYREQRRGGVGAGAS-V-EEDLIQNLYVLSSHSQLLCFTTKGKVFWLKVYEIPVASRTSKGRPLVNMLKLDDDE
TVTQILPVE---EDKFIFMATRNGVVKKTNLNLFHKKYKSGIKAIRLDDDDKLVGTVITDGDND-LLSSYSGKLIRFHESKVRPMGRTARGVKGITLKGK
--VI-SLMVGDSKTILCLSENGFGKRTKLEDFPSYNRGGQGVIAL--SE-RNGNMVSAVAVD-NDGIMLISDKGTLIRTAISQIPTLGRNTQGVKVITPK
-GKLIEGVRIP-
>tr|J4UXA1|J4UXA1_9GAMM DNA gyrase subunit A OS=SAR86 cluster bacterium SAR86A GN=gyrA PE=3 SV=1
NEDLIPEETRVLTVSRSGYAKTQPLDEYREQRRGGQGAAAS-V-EEDLIQNLYVLSSHVQILCFTTKGKVFWLKVYEIPVASRTSKGRPLVNMLNLDDDE
RVSEILPVE---DDKFIFMATRKGITKKTNLSLFARKWKSGIKAINLDEDDRLVGTAITDGKKE-LLASSAGKLIRFNETKVRAMGRTARGVKGMKLKDR
--LI-SLNVADEKTVLCVSENGYGKKTNLDDFPTHNRGGQGVISI--SE-RNGMMVAATLVN-EDGIMLISDKGTMIRTNVSQVPTLSRNTQGVKIITPK
-NKLTECVTIP-
>tr|J4X573|J4X573_9GAMM DNA gyrase subunit A OS=SAR86 cluster bacterium SAR86B GN=gyrA PE=3 SV=1
NEDLIPEETRVLTVSRSGYAKTQPLDEYREQRRGGQGAAAS-V-EEDLIQNLYVLSSHDQILCFTTKGKVFWLKVYEIPVASRTSKGRPLVNMLKLDDDE
RVSDILPVN---DEQYIYMATKKGTNKKSNLSFFAKKYKSGIKAINLDDDDRLIGTAITNGQDE-LLASSSGKLIRFHESKVRPMGRTARGVRGMKLKGS
--LI-SLMVADTKTVLCVSENGYGKKTKLDDFPTHNRGGQGVISI--SE-RNGLMVSAKLVE-DDGIMLISDKGTMIRTNVNQVPTLSRNTQGVKIISPK
-GKLIECVNIP-
>tr|U2W7Y2|U2W7Y2_9FIRM DNA gyrase subunit A OS=Oribacterium sp. oral taxon 078 str. F0263 GN=gyrA PE=3 SV=1
DEDLIPDDDIVISSTRLGYIKRMSPENFRQQNRGGKGIRGMQT-DNDNIEDLFMSTNHHYIMLFTNKGRCFRIKGYEIPES-RTSRGTALVNLLKLQPEE
RVNACFSLRS--SEQYLVLATKSGLVKKTPLSQYANVRKNGLIAMNIREDDQLIEAKLVDPGEEIMLVTKKGMAIRFR---IRSTGRSAMGVRGIRLD--
-ELIGMQKL--GSHLLLVSEKGYGKLTATEEFKPQNRGGKGLHCYRITE-KTGDLVGFKLCD-DREIMLITSEGILIRMSLGKVSV-GRNTSGVKFMDLP
NGTVIASIAKV-
>tr|W3ALA1|W3ALA1_9FIRM DNA gyrase subunit A OS=Lachnospiraceae bacterium JC7 GN=gyrA PE=3 SV=1
DEDLIPDDDTVIAATRLGYIKRMSPENFKQQNRGG-G--KMQ--DD-IIEDLFMTTNKHYIMFFTNMGRCFRIKAYKIPES-RTSRGTAMVNLL-QAD-E
Y--ASFAIS--DSDQYLLLATKNGTVKKTPISQYSN-R-SGLIAISLR--DRLIE---IE---DIMIGTRNGMAI------VRITGRSSFGVRGISLSD-
-DVVGMQK---GDFVLVVSEKGMGKLTSV-EFK-QKRGGKGLRCY---TEKTGNV-GFKLTD--REIMLITNEGVIIRMSL-DAKD-GR---GVKFMNIE
D-VVIASIAKV-
>tr|F5T884|F5T884_9FIRM DNA gyrase subunit A OS=Oribacterium sp. oral taxon 108 str. F0425 GN=gyrA PE=3 SV=1
AEDFISDDDVVITSTSLGYIKRMSPEHFHQQNRGG-G--KMQ--ND-YIEDLFMTTNHHYVMFFTNQGRIFRIKGYEIPES-RTARGTALVNLL-SQN-E
K--ATLCLR--NEEKYLILTTKKGIIKKTELSQFAN-R-NGMIAITLN--DQLIE---LE---EIFLVTKKGMAI------VRATGRSSMGVRGIRLNA-
-DVIGMQE---GEHFLLVSEKGYGKLTDK-CFK-QARGGKGIRCY---TEKTGDV-GFKLCD--REILLITTEGIMIRINL-KVSI-GR---GVKLMDID
D-TVIASVAKV-
>tr|A0A0R2HY37|A0A0R2HY37_CARDV DNA gyrase subunit A OS=Carnobacterium divergens DSM 20623 GN=IV74_GL000047 PE=4 SV=1
DEDLIEEEDIVITLTHNGYIKRLPNNEFRAQRRGGRGVQGMGM-DDDFIENLVSCSTHDTLLFFTNNGKVYRAKGYEIPEYGRTAKGIPAINLLGI-DGE
KIQAIINVK---EDTYLFFTTLKGVVKRTSVSAFSN-RSNGLKAIVLREDDELMNVC-TNG-QNVIIGTHLGYAVSFDE--VRDMGRSASGVRGIRLR--
-DVVGMDVLKADSEVLVITENGYGKRTKASEYPIKGRGGKGIKTANIT-E-NGKLAGLTTVND-EDIMLITNTGVIIRFEVDSVSQTGRATLGVRLIRVG
D-IVSTMAKVE-
>tr|A0A0F2NQI4|A0A0F2NQI4_9FLAO DNA gyrase subunit A OS=Flavobacteriales bacterium BRH_c54 GN=gyrA PE=3 SV=1
IEDMIPDETVVVTISHLGYIKRTSLSEYKLQNRGGVGAKGSAT-DEDFLENLFVATTHNYLLVFTEKGKCYWMRVFEIPEGTKQSKGRAIQNLINIETDD
KVLAYINVKK--NNNFIIMCTEKGVVKKTTLEAYSR-RVNGINAITVREGDRLLEAKLTSGSDEILLALKSGKAIRFN---TRPMGRNASGVRGIRLAE-
-DVIGMIAINDSRNILVVSENGYGKRSELE-YRVTNRGGKGVKTINITD-KTGGLIAMKDVS-NDDLMIINKSGLVIRLAVETLRVMGRATQGVRLINLK
-NSIAAVAKVE-
>tr|A0A0P7Z831|A0A0P7Z831_9BACT DNA gyrase subunit GyrA OS=Bacteroidetes bacterium HLUCCA01 GN=gyrA PE=4 SV=1
IEDMIADEDVVVTISNTGYIKRTPVSGYRRQKRGGTGSRGATT-DEEYIEHLFVATNHNYILFFTEKGKCYWLKVYEIPEGTRLSRGRAIVNLIQIDK-D
HVKTFVPVKE-IKNHFIMMGTKKGIVKKTSLEAYSR-RRDGIIAINIDDGDHLLEAR-TDG-STIILGAKNGRAIRFQE--VRDMGRNTRGVRGINLD--
SDMVDMVVVKNEATVLAISENGYGKRSQVQDYREQSRGGKGVITMKIT-S-TGNLIALKEVSH-DDLMVITKKGKIIRMHCKDIRSMGRNTQGVRIIRLT
-DKIGGVTRVV-
>tr|A0A0L7NG67|A0A0L7NG67_CLOBO DNA gyrase subunit A OS=Clostridium botulinum GN=gyrA PE=3 SV=1
IEDLIEEKDVVITLTHAGYIKRLPVETYSAQKRGGRGIQAMTT-EDDFVEHIITASTHDNILFFTNLGRVYQLKAYQIPEG-RTAKGMNLINLIPLDK-E
KIQNVIYLK---KDKFLIMGTKKGLIKKTSLDKYAS-RKNGLNAINLREDDELVSAR-TTG-CNIIYATKNGYAIRFHE--VRPMGRTATGVKAITLR--
-DVVSMEVASE-RDFLVVSENGYGKRTPIDQYTLQKRGGKGVITYKIS-E-TGLLIGARSVEQ-DELMLINDSGIAIRINVSDISTTSRNAMGVTLMRTV
NE-VVTMAKVN-
>tr|C6Q077|C6Q077_9CLOT DNA gyrase, A subunit OS=Clostridium carboxidivorans P7 GN=CcarbDRAFT_4444 PE=3 SV=1
IEDLIQEQEVVVTLTHAGYIKRIAADTYSAQKRGGKGIQAMTT-EDDFVEHMFVTSTHNNILFFTNRGRVYKLKGYELPDG-RTAKGVNLINLLPIET-E
KIQAVITFK---KTNYFIMGTRQGLIKKTQVSQYSS-RKNGLNAINLREDDELIGVR-TTG-SEILVFTKNGYAIRFNE--VRPMGRTATGVKAITLR--
-EAVAMDIVCE-QDVLVISENGFGKRTPVSEYTPHRRGGKGMITYKIT-E-TGAIVGARVVKE-DEMMLVNSSNVAIRLNVSGISTTSRNAMGVTLMRTD
EQ-VVAIAKIN-
>tr|D8GK03|D8GK03_CLOLD DNA gyrase subunit A OS=Clostridium ljungdahlii (strain ATCC 55383 / DSM 13528 / PETC) GN=gyrA1 PE=3 SV=1
IEDLIEEQEVVITLTHSGYIKRISADTYSSQRRGGKGIQAMST-EDDFVEHIFITSTHNNILFFTNKGKVYKLKGYEIPDG-RTAKGTNLVNLIPLQG-E
QIQAVISFK---KDNYFIMATRCGLIKKTKISQYAS-RKNGLNAINLKDEDELIGVR-TTG-SEILIFTKNGYAIRFSE--VRPTGRNTTGVRAITLR--
-GAVAMDIVDK-QDVLVISENGFGKRTPVSEYTIHRRGGKGIITYKVT-E-TGLIVGARVVKE-DEMMLINSSNVAIRLNVSEISVTNRNTMGVTLMRTD
EQ-VVAIAKIN-
>tr|A0A0L6ZBH7|A0A0L6ZBH7_9CLOT DNA gyrase subunit A OS=Clostridium homopropionicum DSM 5847 GN=gyrA_2 PE=3 SV=1
LEDLIEEKDLVITLTHAGYIKRLPIETYSAQKRGGRGIQAMAT-EDDFVEHIMTTTTHNNILFFTNLGKVYQLKAYQIPEG-RTAKGMNLINLIPLGQ-E
KIQAVLYIN---ENSHLVMGTKKGLIKKTSLSEYSS-RKNGLNAINLKEDDELISVR-TTE-CQIIYVTKNGYAIRFNE--IRSLGRTASGVKAINLR--
-DVVGMEVATK-QDLLVVSENGYGKRTPIEEYTLQKRGGKGLITYKIS-E-TGKVIGARLVSG-EELMLINTNGIAIRINVSDISTTSRNAMGVTLMKTT
EE-VVAMAKVN-
>tr|A0A0M0AFB8|A0A0M0AFB8_CLOBO DNA gyrase subunit A OS=Clostridium botulinum GN=gyrA PE=3 SV=1
IEDLIQEEDVVITLTKSGYIKRISADVYSAQRRGGRGIQAMST-EDDFVDHVMITSTHSDVLFFTNRGRVYKLRAYEIPDG-RQAKGTNIINLIAIEP-E
KIQTVLTVT---RDGYLFMGTKQGIVKKTHLNEFRN-RKNGLIAINLRENDELLKVK-TYG-ANVMFVTQNGYALRFNE--VRHMGRTASGVKAITLK--
-DAVCMDIAVD-EELLVISENGFGKRTPVKEYKVQHRGGVGLITYKIS-E-TGKLVGATICKD-DELMLINTNGVAIRINVSDISKTSRSAMGVTLMRTN
EE-IVAIAKIL-
>tr|K6U725|K6U725_9CLOT DNA gyrase subunit A OS=Clostridium sp. Maddingley MBC34-26 GN=gyrA PE=3 SV=1
IEDLIQEEDVVITLTHSGYIKRISADTYSAQRRGGKGIQAMTT-EDDFVEHLMITSTHSDVLFFTNKGRVYKLRAYEIPDG-RQAKGTNLINLIAIES-E
KIQTVLTVT---KEGFLFMGTKQGIVKKTPLSEFKN-RKNGLIAISLKDGDELLKVK-TYG-ANIMVVTQNGYAVKFNE--VRSMGRTASGVKAINLK--
-DAVCMDIAVD-EELLVISENGYGKRTPIAEYKLQNRGGVGLITYKIS-E-TGKLAGATICKD-DELMLINSSGVVIRINVSDISVTSRSAMGVTLMRTS
DE-VVAIAKIL-
>tr|R5BCL4|R5BCL4_9BACE DNA gyrase subunit A OS=Bacteroides sp. CAG:927 GN=gyrA PE=3 SV=1
AEDFYPDDDMIITISHLGYIKSTALSEFRAQNRGGVGAKGSDT-DEDFIEHIYAASMHSYMLFFTQKGRCYWLKVYEIPESAKNTKGRAVQNLLNIEADD
AINAIICVKE--ENHNLVFATKNGVIKKTKLEAYSR-RAAGVNAIVIRDDDQLISVEMTDGNSEILLANRNGRAIRFP---VREMGRVSTGVRGMTLDP-
-DVVGMICMNPPDTVMVVSENGYGKRSVLDDYRITNRGGKGVKTLNITD-KTGKLVAIKSVN-ENDLVIINKSGITLRVKMSDIRIQGRATQGVKIINLE
RNTIASVCCVD-
>tr|A0A0R2ASB9|A0A0R2ASB9_9LACO DNA gyrase, A subunit OS=Lactobacillus ozensis DSM 23829 = JCM 17196 GN=FD06_GL001055 PE=4 SV=1
DEDLIEEEDVIVTLTHKGYVKRIATSEFRSQNRGGRGVKGMGV-NDDFIENLISTTTHHNLLFFTNTGKVYSMKGYEIPEYGRSAKGIPIINLLGI-EDE
TIQAVITIS--YDDKFLFFTTLHGTVKRTPVEEFSN-RNNGLKAIHLKDNDELIRVS-VSE-DNMILGTHAGYSASFKV--VRSMGRTATGVRGIRLR--
-DVIGAAMLNPSDNVFVISEKGYGKQTAATEYAIKKRGGKGIKTVNVT-E-NGPLAGLTTVSK-EDIMLVTDKGVIIRFNIDDVSQTGRATLGVHLIKIA
D-KVSTMAKVI-
>tr|A0A0P7J7S8|A0A0P7J7S8_9LACO DNA gyrase subunit A OS=Lactobacillus kunkeei GN=gyrA PE=4 SV=1
DEDLIAEEDIMITLTHNGYIKRTATSEFKSQNRGGRGVQGMGV-DDDFIEHLLATTTHHSLLFFTNLGKVYRMKGYEIPEYGRSAKGIPIINLLGI-DDE
KIQAVIPVD--NDGRFLFFTTLKGTVKRTPIDEFQN-RSNGLKAIHLKDEDELMRVS-VSE-QNIIIGTHLGYCVSFKV--VRSMGRSATGVRGIRLR--
-NVVGGDVLDPNDNVFVISENGYGKQTPASEYQIKGRGGKGIKTVKVT-E-NGPLAGLTTVTD-EDIMLVTDKGVMIRFSISDVSQTGRATLGVHLIKID
D-RVSTVARVQ-
>tr|A0A090BWM5|A0A090BWM5_9ENTR DNA gyrase subunit A OS=Candidatus Tachikawaea gelatinosa GN=gyrA PE=3 SV=1
IEDLILQKDVIVTLSHKGYVKYQPLNDYAAQHRGGKGSAAK-TKEEDFIDRLLVTKTHDTILCFSNRGRLYSMKVHQLPEANRYSRGRPIVNLLPLE-NE
RITAILPINEYKEEINIFMASAKGTVKKTAISELIRSRNAGIIAVNLREDDELIGVAFTKGTNTILLFSSTGKVVCFNESSVRTMKRTASGVRGIKLA--
KDVVSLIVSNEPGTILTVTKKGYGKRTEINKYPIKSRGTRGVISIKVTQ-RSGPVISAIQVFENDQIMIITDTGKLVRIRVSEVSTLGRNTQGVILIRTL
KESVVGLQRVV-
>tr|I3C143|I3C143_9FLAO DNA gyrase subunit A OS=Joostella marina DSM 19592 GN=gyrA PE=3 SV=1
IEDMIPDEQVVITISHAGYIKRTPLTEYKTQNRGGVGQKGTST-TEDFLEHLFVGTNHQYMLFFTQKGKCFWMRVYEIPEGSKTSKGRAIQNLINIEQDD
KVKAFICTKK--NSHFVIMATKKGVVKKTSLEQYSR-RQNGINAITVRDGDELLEAKLTTGNSQILLAVKSGKAIRFE---TRPMGRNASGVRGITLADN
-DVVGMVSVHNEENILVVSEKGYGKRTYLDVYRITNRGGKGVKTMSITE-KTGALVAIKNVS-EDDLMIITKSGVAIRMAIEDLRVMGRATQGVKLINLK
--SIAAVAKVM-
>tr|A0A068DRZ5|A0A068DRZ5_9BACT DNA gyrase subunit A OS=endosymbiont of Llaveia axin axin GN=gyrA PE=3 SV=1
MKDLILNEYVVLTISHHGYIKRTPLSEYKRQLRGGIGNIGAKT-DEDFLEHLFVATNHQYTLFFTKKGKCFWLRVYEIPEGSKTSKGRAIQNLIRLSPDD
RICAYILSGD--KNRYVIMVTESGIIKKTPIKKYSR-RRNGINAITIREKDTLLEAELTTGNSEVLIAVKSGKAIRFS---VRPMGRMACGVKGIRMSE-
-DVIGMVCVKP--DILVVSEKGYGKRSFLE-YSITNRGGKGVKTINITK-KTGKLISITSVY-TSDLMIITKDGITIRISVSDIRISGRSTQGVRLINLR
-GEIAAVAKVG-
>tr|C0BH88|C0BH88_FLABM DNA gyrase subunit A OS=Flavobacteria bacterium (strain MS024-2A) GN=gyrA PE=3 SV=1
MEDMIPDEQVVITISHAGYIKRTPLIEYKTQNRGGVGQKASTT-DEDFLQDLFVGTNHQYMLFFTQKGKCFWMRVYEIPEGSKTAKGRAIQNLINIEQDD
KVQAFICTQK--NNHYVIMATKKGQVKKTSLEQYSR-RANGINAINVREDDELLEAKLTNGNSHVMLAVKSGKAIRFE---TRPMGRGASGVRGITLAS-
-DVVGMVAVNDDANILVVSENGYGKRSSLD-YRITNRGGKGVKTISITD-KTGKLVTIKTVT-TDDLMIINKSGIAIRMEVAALRVMGRATQGVRLINLK
-DTIAAVAKVM-
>tr|A0A0R2VNY1|A0A0R2VNY1_9SPHI DNA gyrase subunit A OS=Sphingobacteriales bacterium BACL12 MAG-120813-bin55 GN=ABR95_09655 PE=4 SV=1
IEDLINEEDVVITISHMGYIKRTLASEYRVQGRGGTGFRGVAA-DEDFIEHLFVASTHDTMLFFTKMGKCFWLPVYQIPEGSRTSKGRAIQNMISLPPGD
KVMAFIDVRK--NNHFVVFCTRKGVIKKTALEAFSR-RTNGIAAISINEGDELLEVKMTDGNCEVMLAVRSGRAIRFP---VRPMGRTAAGVRGVLLES-
-DVVGMISVEKESTILVVSENGYGKRSYITVYRITNRGGKGVNTIKVTE-KTGALIAIKSVT-NDDLMIMTEKGIAIRMSVNDIRVMGRATQGVRLINLK
-NRIASVAKAE-
>tr|S2WB84|S2WB84_9FLAO DNA gyrase subunit A OS=Capnocytophaga granulosa ATCC 51502 GN=gyrA PE=3 SV=1
IEDIIPNEQVVITISNAGYIKRTSVNEYKTQARGGVGQKASAT-DKDFIEHLFVGTNHQYMLFFTEKGKCFWLRVYEIPEGGKNTKGRAIQNLINIASDD
LVKAVICTHK--NSHYVVMATKKGVIKKTCLEQYSR-RQNGIVAITIKEDDELLEARLTSGNSQVMLAVKSGKAIRFP---VRAVGRSGSGVRGISFDEA
-DVIGMITIEN--TVLVVSENGYGKRTFIDVYRITNRGGKGVKTISVTE-KTGNLVAIKSVL-EDDLMIINKSGMAIRLPVSDLRVMGRATQGVRLINIK
-NSIAAVAKVM-
>tr|A0A0Q9ZAW7|A0A0Q9ZAW7_9FLAO DNA gyrase subunit A OS=Salegentibacter mishustinae GN=APR42_04880 PE=4 SV=1
IEDMIPDERVVITISHAGYIKRTSLNEYKTQNRGGVGQKGSNT-NEDFLEYLFSGTNHQYMLFFTQKGKCFWMRVYEIPEGSKASKGRAIQNLINIDPDD
RVKAFICTQK--NKHYVIMATKKGQVKKTSLEQYSR-RTNGINAITIKEDDELLEAKLTNGDSQVMLAVRSGKAIRFE---TRPMGRNASGVRGITLAD-
-DVVGMISVEDNSDILVVSENGYGKRSSLE-YRITNRGGKGVKTISITE-KTGSLVAIKNVS-DEDIMIINKSGIVIRMEVSNLRVMGRATQGVRLINLK
-NAIAAVAKVL-
>tr|H2BYK6|H2BYK6_9FLAO DNA gyrase subunit A OS=Gillisia limnaea DSM 15749 GN=gyrA PE=3 SV=1
IEDMIPDEQVVITISHAGYIKRTSLTEYKTQNRGGVGQKGSTT-NEDFLEYLFSGTNHQYMIFFTQNGKCYWMRVYEIPEGSKTSKGRAIQNLINIEPND
KVKAFICTQK--NSHYVIMATKKGQVKKTSLEQYSR-RVNGINAITIREDDELIEAKLTNGESQVMLALKSGKAIRFE---TRPMGRNASGVRGITLAD-
-DVVGMIAVNDEANVLVVSENGYGKRSKLE-YRITNRGGKGVKTISVTE-KTGELVTIKNVT-KDDLMIINKSGLAIRMSIENLRVMGRATQGVKLINLK
-NAIAAVAKVM-
>tr|A3XM11|A3XM11_LEEBM DNA gyrase subunit A OS=Leeuwenhoekiella blandensis (strain CECT 7118 / CCUG 51940 / MED217) GN=gyrA PE=3 SV=1
ITDLIPDEKVVLTISHAGYVKRTSLMEYKTQNRGGVGQKGSTT-NEDFLEHLFVGTNHQYLIFFTEKGKCFWVRVFEIPEGSKTSKGRAIQNLINIEPDD
KVKAFICTNK--NSHYVIMATKKGQVKKTSLEQYSR-RTNGINAITIKEGDELLAAKLTTGDSQVMLAVKSGKAIRFE---TRPMGRNASGVRGITLAD-
-DVIGMVAVNDESNVLVVSENGYGKRSLVE-YRVTNRGGKGVKTISVTE-KTGNLVAINNVT-EDDLMIINKSGIAIRMEVSELRVMGRATQGVRLINLK
-GTIAAVTKVK-
>tr|A0A0D6TJS3|A0A0D6TJS3_9FLAO DNA gyrase subunit A OS=Flavobacterium sp. 316 GN=gyrA PE=3 SV=1
IEDLIADEQVVVTISHAGYIKRTSLTEYKTQNRGGVGQKSAAT-DQDFLEHLFVATNHQYLMYFTQKGKCYWMRVFEIPEGTKASKGRAIQNLINIEKDD
KVKAFICTKK--NSHYVIMATKQGQVKKTSLEQYSR-RQNGINAITIKEDDELLEAKLTTGNSHVLLAVKSGKLVRFE---TRPMGRTASGVRGITLAE-
-DVIGMVSIDEDSQILVVTENGYGKRTKL-VYRVTNRGGKGVKTLNLTE-KTGALIAINAVT-EDDLMIINKSGLTIRMEISDLRVMGRATQGVRLINIK
-KSIAAVTKVL-
>tr|A3U9V0|A3U9V0_CROAH DNA gyrase subunit A OS=Croceibacter atlanticus (strain ATCC BAA-628 / HTCC2559 / KCTC 12090) GN=gyrA PE=3 SV=1
IEDMIPNEKVVITISHAGYIKRTPLTEYKTQNRGGVGQKASTT-NEDFLEDMFVGTNHQYMIFFTQKGRCFWMRVFEIPEGSKTSKGRAIQNLINIEPDD
KVKAFICTQK--NSHYVIMATKKGQVKKTSLEQYSR-RINGINAITIKEDDELLEAKLTTGDSEIMLAVKSGKCIRFE---TRPMGRSASGVRGIRLAEK
-DVVGMVVVNNDSDILVVSENGYGKRSSLE-YRMTNRGGKGVKTISVTS-KTGELVAIKNVT-DDDLMIINKSGIAIRLSVENLRVMGRATQGVRLINLK
-DAIAAVAKVK-
>tr|A9E3P5|A9E3P5_9FLAO DNA gyrase subunit A OS=Kordia algicida OT-1 GN=gyrA PE=3 SV=1
IEDLIPDEKVVITISHAGYIKRTSLTEYKRQNRGGVGQKGSAT-NEDFLEHLFVGTNHQYMLFFTQQGKCFWMRVYEIPEGSKTSKGRAIQNLINIEKDD
KVKAFICTQK--NNHYVIMATKKGQVKKTPLEQYSR-RTNGINAITIKDGDELLEAKLTTGNSQVMLAVKSGKAIRFE---TRPMGRNASGVRGIRLAD-
-DVVGMVAVNDESNILVVSENGYGKRSSLE-YRITNRGGKGVKTISVTE-KTGQLVAIKNVT-EDGLMIINKSGIAIRMAVADLRVMGRATQGVRLINIK
-KSIAAVAKVR-
>tr|A0A0A3IQ13|A0A0A3IQ13_9BACI DNA gyrase subunit A OS=Lysinibacillus odysseyi 34hs-1 = NBRC 100172 GN=gyrA PE=3 SV=1
DEDLIPRENSVVTLTHNGYIKRLAANTYRSQKRGGRGVQGMGT-ENDFVEHLLSTSTHDTILFFTSKGRVFKAKGYEIPEFGRTAKGLPIVNLLNIEK-E
HVTAMIRIE---EDAFFIFTTKTGITKRTPVSQFAN-RTNGLIAISLREDDDLISVR-TDG-KQVIIGTHDGMLVRFQE--IRSMGRTASGVRGIKLR--
GDVVGMEILEEGQEILVVTEKGYGKRTPESEYRLQSRGGVGIKTIQVT-EKNGPMCAVKTVDA-EDIMLITINGMLIRMDVNDISIIGRSTQGVRLIRLS
-ELVATVAKVN-
>tr|K1KI94|K1KI94_9BACI DNA gyrase subunit A OS=Bacillus isronensis B3W22 GN=gyrA PE=3 SV=1
DEDLIPRENSVLTLTHNGYIKRLAANTYRSQKRGGRGVQGMGT-EDDFVEHLLFTSTHDTILFFTSKGKVFRAKGYEIPEFGRQAKGLPIVNLLNIDK-E
HVTAMIRVT---EDAYFIFTTKTGVTKRTPVDQFAN-RTNGLIAITLREDDDLISVH-TDG-KEIIIGTSDGMLVRFKE--IRSMGRSAAGVRGIKLR--
GDVVGMEILEPGQEILVVTENGYGKRTPESEYRLQSRGGLGLKTMQIT-DKNGKMCAVKAVDS-EDIMLITINGMLIRMDVNDISVIGRSTQGVRLIRLA
-GYVATVARVK-
>tr|A0A0A3J7X4|A0A0A3J7X4_9BACI DNA gyrase subunit A OS=Lysinibacillus massiliensis 4400831 = CIP 108448 = CCUG 49529 GN=gyrA PE=3 SV=1
DEDLIPREDSVVTLTHNGYIKRLASNTYRSQKRGGRGVQGMGT-EDDFVEHLLFTSTHDAILFFTSKGKVFLTKGYEIPEYGRTAKGLPIVNLLNLDK-E
KVTAMIRSE---EDAYFIFTTKTGITKRTPLSQFAN-RKNGLIAISLHDDDELISVR-TDG-KDVIIGTREGMLIRFKE--IRSMGRTAAGVRGIKLR--
GDVVGMEIIEEGQEILVVTEKGYGKRTPESEYRLQSRGGVGLKTIHIT-EKNGPLCAVKTVDT-EDIMLITINGILIRMDVNDISVIGRSTQGVRLIRLG
-DFVATVARVK-
>tr|F7PT51|F7PT51_9BACT DNA gyrase subunit A OS=Haloplasma contractile SSD-17B GN=gyrA PE=3 SV=1
DEDLIPQEDIIITVTSRGYVKRLPVDTYKSQNRGGVGMKGMAT-EEDFVEHMIFTSSHDKILVFTNLGKVYKLRGFSFPQG-RNAKGMPLVNLLSLEE-E
KLNAIIPIK--E-RDYLVFATRNGTVKRTELSLYAN-RVNGIKAININDDDELMAVR-TNG-KEVIIGSSDGKLVRFIE--VRSMGRTATGVRGINLD--
-DAVGMDTIQDDQLVLSISEYGYGKLTPISEYRLSHRGGKGVKTINIT-D-NGKLVTVRAVTG-HDLMIVTNKGMVIRTPIEQISITGRATLGVRLINLK
DQ-VASAAIIP-
>tr|A0A0A3HS91|A0A0A3HS91_9BACI DNA gyrase subunit A OS=Lysinibacillus sinduriensis BLB-1 = JCM 15800 GN=gyrA PE=3 SV=1
DEDLITREDSVLTLTHNGYIKRLASNTYRSQKRGGRGVQGMGT-DDDFVEHLLFTSTHDTILFFTTKGKVYRAKGYEIPEFGRTAKGLPIVNLLNLEK-E
KVTAMIRVD---EDAYLIFTTKTGITKRTQLSQFAH-RTSGLIAINLHDDDDLISVR-TDG-KDVIIGTHDGMLIRFKE--IRSMGRTASGVRGIKLR--
GDVVGMEIIEPGHEILVVTERGYGKRTPESEYRLQSRGGVGLKTIQIT-DKNGPMCAVKTVDT-EDIMLITINGILIRMDVNDISVIGRSTQGVRLIRLG
-ELVATVARVK-
>tr|A0A0C2SGW4|A0A0C2SGW4_9BACL DNA gyrase subunit A OS=Jeotgalibacillus campisalis GN=gyrA PE=3 SV=1
DEDLIPRENLILTLTHNGYIKRLPASTYRSQKRGGRGIQGMGT-ENDFVEHLLTTSTHDTILFFSNKGKVYRTKGYEIPEYSRTAKGLPIINLLGIDK-E
DINAMIRVE---EDSFFFFTTKYGISKRTPVSDFAN-RTNGLIAINLREGDDLISVK-TDG-KEIIIGTQNGLLIRFPE--VRSMGRTATGVRGIRLK--
EDVVGMEILEPDNEILVVTENGYGKRTTEKDYRVQSRGGKGIKTCNIT-DKNGKLIAVKTVTD-EDVMIITVNGVLIRMDVSGISQTGRSTQGVKLIRLG
-QYVATVTRIE-
>tr|A0A0C1R5K7|A0A0C1R5K7_9ACTN DNA gyrase subunit A OS=marine actinobacterium MedAcidi-G1 GN=gyrA PE=3 SV=1
IEDLIDDEELIFAMTSAGYVKTMALSDFNAQGRGGKGVTGAKL-DEDALSHMIHTTAHAYLLFFSNKGKVYRLKAHEIPSASRTARGTPIVNLLPLP-DE
RIQAVVDTR---TNRFLFFATKNGRVKKTLFTAYDSSLKAGLIAIKLNEGDELVSVV-TNGSDHIFLVSSMGQTLRVDE--IRSMGRTAAGVNGMKFR--
-YLVSCAV---EAMLLHLTTEGFGKRTEVEEFSVKGRGGLGVRGI--TN--RGTVAGALIVKGDDDILAVTSSGKIIRLAVSEISIQGRDATGVRVMSPG
-GIITAVSPAP-
>tr|A0A0C2VEC5|A0A0C2VEC5_9BACL DNA gyrase subunit A OS=Jeotgalibacillus alimentarius GN=gyrA PE=3 SV=1
DEDLIPQENLIVTLTHNGYIKRLPASTYRSQKRGGRGIQGMGT-EDDFVEHLLTTSTHDTILFFTNKGKVYRAKGYEIPEFSRTAKGLPLVNLLEVDK-E
VVNAMIRVE---EKSYFFFTTKRGISKRTPATDFAN-RNNGLIAINLRDDDELISVK-TDG-REIIIGTKNGLMIRFPE--VRSMGRTAGGVRGIRLN--
DDVVGMEILGEGNDILVVTEKGYGKRTPEEEYRVQSRGGKGIKTCNIT-EKNGRLVAVKAVTE-EDIMLITAHGVLIRMDVSGISQTGRSTQGVKLIRLG
-EHVATVTRIE-
>tr|A0A0C2RG65|A0A0C2RG65_9BACL DNA gyrase subunit A OS=Jeotgalibacillus soli Cunha et al. 2012 GN=gyrA PE=3 SV=1
DEDLIPRENLIITLTHNGYIKRLPASTYRSQKRGGRGIQGMGT-ENDFVEHLLTTSTHDTILFFTNKGKVYRTKGYEIPEYSRTAKGLPIINLLEIEK-E
VINAMIRVE---EDSFFFFTTRYGVSKRTPVSDFAN-RTNGLIAINLKEGDELISVK-TNG-KEIIVGTKNGMLIRFPE--VRSMGRTATGVRGINLN--
DDVVGMEILEPGNNILVVTEKGYGKQTPEEDYRVQSRGGKGIKTCNIT-DKNGKLVSVKAVTQ-EDLMLITGQGVLIRMDVSDISQTGRNTQGVKLIRLG
-QYVATVTRIE-
>tr|A0A024F9E3|A0A024F9E3_UREPR DNA gyrase subunit A OS=Ureaplasma parvum serovar 3 GN=gyrA PE=3 SV=1
DEDLIPVEDIVVTMSKRGYFKRLPIDTYKNQRRGGVGVQGLKT-EDDDVEKILVANTHTDLLFFSDLGRVYRLRGHEVPLS-RQSKGIPAINFLPIEKSE
SILTILPID---DQGSLFFTTSKGIIKRANLSDFESIRANGKIAITLKDGDKLFSVMQTLGNDEVFIGASNGNVIRFN---AREMGRIATGVKGINLE--
-YVVGTGLS--GEYVLAVGSKGLGKLTDINDYRLTKRGAKGVNTLKVND-KTGNLVSIKVVN-EEEALIITTSGKVIRLSIKDISV-GRNTSGVKLISLE
-KEVKSIAIFK-
>tr|A0A0C5RCP3|A0A0C5RCP3_9MOLU DNA gyrase subunit A OS=Ureaplasma diversum GN=gyrA PE=3 SV=1
EEDLIPEEDIVITVSKRGYFKRLPIDTYRAQKRGGVGVIGANT-EDDDIDQIIVANTHTDVLFFSDLGRVYRIRGHQIPIS-RTTKGTPAINFLPIQKGE
LIQTILPIN---DEGSLLFTTVKGKVKRGRMDDYKLIYKGGKIAINLPEDDKVFSVMATNGNDEIFISSSSGHLVRFD---IREMGRNSYGVNGIKLT--
-YVVGTGLA--GKYVLAVGKKGIGKLSDCEDYRMTNRGTKGVITLKVNS-KTGPLVGIKVVD-DDELLIITSSGKIIRTRINEISI-GRNTSGVKLVSLD
-KEIKSITIFK-
>tr|K9VR34|K9VR34_9CYAN DNA topoisomerase (ATP-hydrolyzing) OS=Oscillatoria nigro-viridis PCC 7112 GN=Osc7112_5751 PE=4 SV=1
LPV-LEAEETIVEFSHKQYVRRLPAGE--KPRSKS-E--S-SA-ED-FIVTADLTKTDRTLVVLTPNGKAYPLKVADIPSS-AKDRGTPIVSLLSPSS-A
GRAAHFILP--E-AADLVTLTQQGKIKRLPMQEFAD-T-RGVTVVKLK--DRLRC---K----QVAIATSGGRVL------LPPMGRSAQGSQVTRLR--
-QLVGCITLD-EDSLVLISELGWAKRMPA-SVR-TNRGEIGTQAF--SPK---DL-GLLPAV-GTDVKLFTNSGRLLRSAI-AIAF-GK---GDRVFDLS
G-KIIKVISSQ-
>tr|A0A073CIR3|A0A073CIR3_PLAAG DNA topoisomerase (ATP-hydrolyzing) OS=Planktothrix agardhii NIVA-CYA 126/8 GN=gyrA PE=4 SV=1
QPLPPVDEETVIEITHRGYIRRVSPKTADSKRNQT-N--T-IN-DD-FITQTHNTKTSQNLVMVLKTGKAYPLSVADIPVN-NRSKGKPIITLLSPST--
SINAQFLLS--D-KTDLITLTQQGKIKRLPLIELAE-T-RGSTIVKLK--DELSF---N----KVVLATSGGRLL------LPPMGKVAQGSQATRLR--
-KLIGCVTLS-KGSLLLVTEQGYIKRIAM-LVR-SNRGGIGISMI--KPN---DL-GIAPAK-RQQIHLLTSDNRIIHVPT-QINL-TK---GDRIFKLK
D-RIISIKS---
>tr|A0A0G0JET3|A0A0G0JET3_9BACT DNA gyrase subunit A OS=Microgenomates (Roizmanbacteria) bacterium GW2011_GWC2_37_13 GN=gyrA PE=3 SV=1
DEQLIENKEVIVVLTKEGYIKQVPKESFRVQQRGG-G--TME--SD-NVYFITTAMTHDYMLFFTNQGRVFQNRVWDVPAS-RISKGKAVINLV-ARE-E
K--SILTYD--SEKMFVVMSTKLGTMKKTLFKDYAN-R-NGIIAIRLE--DELLW---TK---NVILVSKFGKAI------IRPTGRASIGVKGMELDK-
-GVIAADVFSDKKNILVIGEKGIGKKTKL-SFK-QHRGGKGVKIA---DDKIGSA-LASIIQ--ETLIMTSTSGQVVKISL-SIPS-SR---GVILMRFS
K-RIVSATPV--
>tr|A0A0G0E028|A0A0G0E028_9BACT DNA gyrase subunit A OS=Microgenomates (Roizmanbacteria) bacterium GW2011_GWC2_34_23 GN=gyrA PE=3 SV=1
DEQLIENKEVIVVLTKEGYIKQIPRETFRLQHRGG-G--SME--TD-NVYYITTAMTHDYMLFFSNQGRVFQTRVWDVPVS-RISKGKAIINLV-AKD-E
K--SILSYS--AKNMFVVMSTKYGTVKKSSFEDYIN-R-NGIIAIRLE--DELLW---TK---NVILASKNGKAI------IRSTGRASIGVKGMDIEP-
-EVIAADVFSDKKDILVLTERGIGKKTKL-NFK-QHRGGKGVKIT---DKKIGSA-FSEILK--TTLIITSALGQIVKMEI-NIPS-SR---GVILMRFS
K-RIVSATSV--
>tr|A0A0G0GPP3|A0A0G0GPP3_9BACT DNA gyrase subunit A OS=Microgenomates (Roizmanbacteria) bacterium GW2011_GWA2_36_23 GN=gyrA PE=3 SV=1
DEQLIENKEVIVVLTKEGYIKQVPRETFRVQNRGG-G--SIE--TD-NVYFITTAMTHDYMLFFTNQGRVFQTRVWDVPVS-RISKGKAIINLI-AKD-E
K--SILTYD--AKNLFVIMSTKLGTVKKTPFQDYAN-R-NGIIAIRLE--DELLL---SK---NVILTSNAGKAI------IRPTGRASIGVKGMDLDS-
-KVVAADVFNDKKNILVIGDRGIGKKTVL-SFK-QHRGGKGVKIA---DDKFGNA-LAQIIN--NTLIITSNTGQVVKISL-SIPS-SR---GVILMRFS
K-KVVSATFV--
>tr|A0A0G0E374|A0A0G0E374_9BACT DNA gyrase subunit A OS=Microgenomates (Roizmanbacteria) bacterium GW2011_GWA2_35_19 GN=gyrA PE=3 SV=1
DEQLIENKEVIVVLTKEGYIKQIPRETFRIQNRGG-G--AME--TD-NVYYITSAMTHDHMLFFTNQGRVFQTRVWEVPVS-RTSKGKAVINLV-AKE-E
K--SILSYN--AKSLFVVMSTKLGTVKKSSFEDYSN-R-NGIIAIRLE--DELLW---TK---NVILVSKNGKSI------IRPTGRASIGVKGMDLD--
-GVIAADVFDDKKDLLVLSDKGIGKKTKL-NFK-QHRGGKGVKTA---DNKFGHA-FAKILE--TTLIITSAMGQVVKMEL-SIPS-SR---GVILMRFS
K-RIVSATSV--
>tr|A9KCT7|A9KCT7_COXBN DNA gyrase subunit A OS=Coxiella burnetii (strain Dugway 5J108-111) GN=gyrA PE=3 SV=2
HEDLIPEEHRVVTLSHEGYIKSQSLSSYQAQHRGGRGLAAA-VKEQDFVKNILVANSHDTILCFSTQGKVYWLKVYQVPQGSRIARGRPIINLLPLVKDE
QISAILPIRAY--SHFVFMATAQGAIKKVSLAEFSQPRTKGKIALALNEGDRLVGVDITDGKKEIMLVTDAGKAIRFHEKEVREMGRSARGVRGIKLKAQ
N-VIALIVVKPKGNILTATVHGYGQRTALDDYRSTGRGGQGVMAIRINS-RNGKVVSAAQVFDDDDVLLISDKGTLVRTRVNEISQMGRNTQGVRLIQLS
QDLLVGMEAIS-
>tr|A0A0H4UTN6|A0A0H4UTN6_9COXI DNA gyrase subunit A OS=Coxiella-like endosymbiont GN=gyrA PE=3 SV=1
NEDLIPEEHLFVTLSHEGYIKSQSLSSYQVQHRGGRGLAAA-VKEQDFVKNILVANSHDTILCFSTYGKVYWLKVYQVPQGGRTSRGRPVVNLLPLA-DE
HISTILSIRHYDKSHFVFMTTAQGSVKKVTLAEFSQPRTNGKIALALKEGDRLVGVDITDGNKEVMLVTDVGKAIRFHENEVREMGRSARGVRGIKLKE-
-QVIALIIVKPGGYILTTTIHGYGQRTTIEDYRPTGRGGQGVIAIRVNR-RNGNVVSAAQVFDNDEVLLISDKGTLVRIRVNEISQMGRNTQGVRLIQLA
QESLVGMEAIS-
>tr|A0A0A8EAP0|A0A0A8EAP0_9COXI DNA gyrase subunit A OS=Coxiella endosymbiont of Amblyomma americanum GN=gyrA PE=3 SV=1
NEDLIPEESLVVTLSYSGYIKSQSLSSYQAQHRGGRGMATA-VKDQDFVKSILVANSHDTILCFSTYGKVYWLKVYQVPQSSRVSYGRPVVNLLPLS-DE
YISAILPIRYCNKSHFIFMTTAKGSVKKVVSSEFFQSRMNGKIALTLKTEDRLVGVDITDGNKEVMLITDAGKAIRFHESEVRAMGRTAHGVCGIKLKE-
-QVISLIIVKPGGYILTATSHGYGQRTAIESYRSTSRGGQGVIAIRINR-RNGNVVSATQVFNNYEVLLISNKGTLVRIRVNEVSQMGRNTQGVRLIQLA
QEILVGMEAIS-
>tr|K2BTV6|K2BTV6_9BACT DNA gyrase subunit A OS=uncultured bacterium (gcode 4) GN=gyrA PE=3 SV=1
NEDLITVEDLVVTLSHEGYIKAQSLESYDAQHRGGRGRATS-VKEEDYVKNLLVANSHHTILCFSTMGKAYWLKTYQVPQGGRVARGQPIVNLLPLE-DE
LITAILPVAQFDENHFIFMATQNGTVKKVALTEFENARSNGKIALSLNEGDRLIGVALTDGKQDIMLVSDAGKAIRFSEEAVRAMGRTATGIRGIKLKN-
-QLIALIIPKKDGTILTVTENGYGQRTEVNDYRECGRGGQGVIAIQTTD-RNGRVVGSIPVQQDSEILLVTNGGTLVRIPVAEINVIGRNTQGVRLINVQ
EGKVVSVEGVD-
>tr|A0A0A2TGJ6|A0A0A2TGJ6_9BACI DNA gyrase subunit A OS=Pontibacillus yanchengensis Y32 GN=gyrA PE=3 SV=1
DEDLIPEETIVVTVTHQGYVKRLPASTYRSQRRGGRGVQGMGT-EDDFVEHLLSTSTHNTLLFFTNKGKVYRAKGYEVPEFSRTAKGIPIINLLEVEK-E
WVNAVIAVE---DDWYLFFTTKHGISKRTTLSQFAN-RRGGLIALGLREDDELISVR-TDG-KHIMIGTKGGYVIRFPE--VRTMGRTAAGVKGISLR--
GDVVSMEMIEDGLQVLNVTTKGFGKRTPANEYRITGRGGKGIRSCNLT-DKNGEVVTVKSVTD-EDIMIITESGVLIRMPVESISQTGRNTQGVRLIRLQ
-DEVATVAQIE-
>tr|A0A0A5ICU4|A0A0A5ICU4_9BACI DNA gyrase subunit A OS=Pontibacillus halophilus JSM 076056 = DSM 19796 GN=gyrA PE=3 SV=1
DEDLIPEETVVVTLTHQGYIKRLPATTYRSQRRGGRGIQGMGT-EDDFVEHLLSTSSHHTLLFFTNKGKVYRAKGYEVPEFSRTAKGIPIINLLGVEK-E
WVNAVIAVD---EESYLFFTTKFGVSKRTSVSQFAN-RKGGLIALNLREGDELISAR-TDG-KDIIIGTKGGYLIRFPE--VRPMGRTASGVKGISLR--
DDVVSMEILEEDVYVLNVTTKGFGKRTPASEYRITGRGGKGILTCNLT-ERNGEVVTVKAVRE-EDVMIITESGVLIRMPVDSISITGRNTQGVRLIRVQ
-EEVATVARIA-
>tr|I0JGX7|I0JGX7_HALH3 DNA gyrase subunit A OS=Halobacillus halophilus (strain ATCC 35676 / DSM 2266 / JCM 20832 / NBRC 102448/ NCIMB 2269) GN=gyrA PE
DEDLIPEETVIVTLTHQGYVKRLPANTYRSQRRGGRGVQGMGT-EEDFVEHLLSTSTHNTLLFFSNKGKVYKAKGYEVPEFSRTAKGIPIINMLNIER-E
WINAVITVE---DDWYLLFTTRNGITKRTTLSQFAN-RRGGLIALGLREDDELISVK-TDG-KDIMIGTKNGYLIRFNE--IRAMGRTAAGVKGISLR--
DDVVSMEILEDDLQVLTVTSKGYGKRTPATDYRITNRGGKGIITCNLT-EKNGYVVATQAVNE-EDIMIITESGVLIRMPLESISETGRNTQGVRLIRLG
-GEVATVARVE-
>tr|A0A0A2UXN6|A0A0A2UXN6_9BACI DNA gyrase subunit A OS=Pontibacillus chungwhensis BH030062 GN=gyrA PE=3 SV=1
DEDLIPEETVIVTLTHQGYIKRLPATTYRSQRRGGRGVQSMGT-ENDFVEHLLSTSTHNTLLFFSNKGKVYRAKGYEVPEFSRTAKGIPIINMLEIEK-E
WINAVISVE---DDWYLFFTTKQGISKRTTLSAFAN-RRGGLIALNLREDDELISVR-TDG-KHIMIGTKGGYLIRFPE--VRTMGRTAAGVKGISLR--
DDVVSMEIIEDGLQVLNVTTKGFGKRTPADEYRITGRGGKGIRTCNIT-EKNGEVVAVKAVTE-EDVMIITEAGVLIRMAVESISQTGRNTQGVRLIRLQ
-GEVATVARIQ-
>tr|R6M7V0|R6M7V0_9FIRM DNA gyrase subunit A OS=Firmicutes bacterium CAG:41 GN=gyrA PE=3 SV=1
IDDLIDEEDIVVTVTHKGYTKRLPVDTYKSQRRGGRGISGLTT-EEDFVEHLFTTTTHHTLLFFTTHGVVYKLKGYQIPE-SRQAKGTAIVNLLPLENDE
KISAMIPIK-FD-GKYLTFITKNGIIKKTNVMDYSKIRNGGLRAIDLDENDELIRVKLTDNTQDIIIATHDGYAIRFN---VRSTGRTTRGVMGIRLH--
-YVIGASVAL-DSQLLTVTENGYGKKTPLDEYRIQSRGGKGIFTYRITE-KTGKLAGMKTVT-NDDIILITSDGVIIRMHTDEISS-SRQTQGVRVMRLD
DGSVMSIARTE-
>tr|A0A0J5H076|A0A0J5H076_9BACI DNA gyrase subunit A OS=Bacillus sp. LL01 GN=gyrA PE=3 SV=1
DEDLIPRQNVVITLTHNGYIKRLPLSTYRSQRRGGRGIQGMGT-ENDFVEHLLTTSTHDTLLFFTNKGKVYRAKGYEIPEFSRTAKGIPIINLLEVEK-E
WINAIIPVE---DDWYLFFTTKHGISKRSPLSQFAN-RKGGLIAIGLRESDELISVK-TDG-KEMIIGTKKGMLIRFHE--VRSMGRTATGVKGISIS--
NDVVGMELLDEGLDVLVVTKNGYGKRTPAEEYRIQSRGGKGIKTCNIT-ERNGEVVSVKTVTE-EDLMLITASGVLIRMSVDGISQMGRNTQGVKLIRLA
-NFVTTVARVD-
>tr|I3E0W8|I3E0W8_BACMT DNA gyrase subunit A OS=Bacillus methanolicus PB1 GN=gyrA PE=3 SV=1
DEDLIPRENIVVTLTHNGYIKRLPVSTYRAQKRGGRGIQGMGT-EDDFVEHLITTSTHDTILFFTNKGKVYRAKGYEIPEFSRTAKGIPIVNLLEVDK-E
WINAIIPVE---ENWYLFFTTKEGISKRSPLSSFAH-RNNGLIALNLREGDELISVR-TDG-KHIIIGTKNGMLIRFPE--VRSMGRTATGVKGISLD--
GDVIGMEVLEENNDILIVTKNGYGKRTPASEYRVQGRGGKGIKTCNIT-KKSGNLVAMKAVTE-EDLMLITAGGVLIRIDVGGISVMGRNTQGVKLIRLE
DNYVATVAKVE-
>tr|R9C9P5|R9C9P5_9BACI DNA gyrase subunit A OS=Bacillus nealsonii AAU1 GN=gyrA PE=3 SV=1
DEDLIPEENIIITLTHNGYIKRLPASTYRAQRRGGRGIQGMGT-EDDFVEQLSSTSTHDTILFFTNKGKVYRLKGYEIPEFSRTAKGIPIINLLGVEK-E
WVNAIIPVS---DDWYLFFTTKEGISKRSPLSSFAN-RNNGLIAVNLREGDELIAVR-TDG-KEMIIGTKNGLLIRFPE--VRSMGRTATGVKGITLS--
DDVVGMEVLEENSEILVVTQYGYGKRTPIDEYRVQGRGGKGIKTCNIT-DKNGNLVSMKVVNE-EDLMIITTGGVLIRMAVSDISTMGRSTQGVRLIKLN
NNFVATVAIVE-
>tr|A0A0M0WTT0|A0A0M0WTT0_9BACI DNA gyrase subunit A OS=Bacillus sp. FJAT-21351 GN=gyrA PE=3 SV=1
DEDLIPRQDIVISLTHNGYIKRLPVSTYKSQRRGGRGIQGMNT-EDDFVEHLLTTSTHDTILFFTNKGKVYRTKGYEIPEYGRTAKGIPIINLLEVDK-E
WVNAIIRVD---DDWYLFFTTKQGISKRTPLSSFEN-RNSGLIALNLREEDELISVK-TDG-RDMVIGTKKGMLIRFNE--VRSMGRTATGVKGITLD--
EDVIGMEILEEQSDVLIITKNGYGKRTPIEEYRVQTRGGKGLRTCNIT-DKNGDVVALKCVSE-EDIMLITVSGVLIRVSVSDISQMGRNTQGVKVIRLG
-EFVSTVAKVQ-
>tr|A0A0A5HPW4|A0A0A5HPW4_9BACI DNA gyrase subunit A OS=Pontibacillus litoralis JSM 072002 GN=gyrA PE=3 SV=1
DEDLIPEETIIVTLTHKGYIKRLPASTYRSQRRGGRGIQGMGT-EDDFVEHLLSTSTHNTILFFTNKGKVYRAKGYEIPEFSRTAKGLPIINLLEVEK-E
WVNAVIPVE---DDWYLFFTTKNGISKRTTLSQFAN-RRGGLIALTLKEEDELISVR-TDG-KHIMIGTKGGYLIRFPE--VRTMGRSAAGVKGISLR--
ADVVSMEIIEDGLQVLNVTTKGFGKRTPAEDYRITGRGGKGVLTCNLT-ERNGDVVAVKSVSD-EDIMIMTEDGVLIRMSVESVSQTGRNTQGVKLISLK
-GEVATVARIA-
>tr|A0A0Q3SIA5|A0A0Q3SIA5_9BACI DNA gyrase subunit A OS=Bacillus sp. FJAT-25509 GN=AN960_03850 PE=4 SV=1
DEDLIPVENIIVSLTHNGYIKRLPVSTYRSQRRGGRGIQGMGT-NDDFLEHLLTPSTHDTILFFTNKGKVYRSKGYEIPEFSRTAKGLPIVNLLEIDR-E
NINAIIPVS---EDWYLFFTTKQGIAKRVPLSAFAN-RTNGLIAINLKEDDDVISVR-TDG-KDIVVGTSKGMMIRFNE--VRSMGRTATGVKAITLS--
DDVVGMEVVEEHLDILVVTELGYGKRTAQEEYRIQSRGGKGLKTLNVT-DKNGKMISLKCVSE-QDLMLITESGVIIRMPIEQISRLGRVTQGVKLIKLD
-EHVATVAIAA-
>tr|A0A075LLN1|A0A075LLN1_9BACI DNA gyrase subunit A OS=Terribacillus aidingensis GN=gyrA PE=3 SV=1
DEALIPVENVVITLTHQGYIKRLPSNTYRSQGRGGRGIQGMGT-EDDFVEHLISTSTHDTILFFTNKGKVYRAKGYEVPEFSRTAKGIPIINMLEIEK-E
WINALIPVK---DDWYLIFTTKQGVSKRTTLSQFAN-RKGGLIALNLREDDELISVR-TDG-KHIMIATKNGYLIRFPE--IRPMGRTAAGVKGITLR--
DDVVSMDIIDEGVDILNVTEKGFGKRTPESEYRITNRGGKGILTSKIT-DKTGQMVSAKPVTE-EDIMIITVSGVLIRMPVSSISSTGRNTQGVILIRIQ
-NAVATVARID-
>tr|A0A084GPC5|A0A084GPC5_9BACI DNA gyrase subunit A OS=Bacillus indicus LMG 22858 GN=gyrA PE=3 SV=1
DEDLIPVENIVITLTHNGYIKRLPISTYRSQRRGGRGIQGMGT-EDDFVEHLLTTSTHDTILFFTNKGKVYRTKGYEIPEYGRTAKGLPIINLLEIEK-E
WVNAIIPVS---DDWSLFFTTKEGISKRSPLSQFAN-RKGGLIAVNLREADELISVR-TDG-KHIMIGTKKGMLIRFPE--VRSMGRTATGVKGITLD--
DDVVGMEILEEDADVLTVTRNGFGKRTPAAEYRVQSRGGKGIKTCNVT-EKNGTVISVKPSTE-EDLMLITASGVLIRMAIDSISTTGRNTQGVKLIKLG
-EHVATVAVVE-
>tr|A0A0K9GHR1|A0A0K9GHR1_9BACI DNA gyrase subunit A OS=Bacillus sp. FJAT-27916 GN=gyrA PE=3 SV=1
DEDLIPQENIVISLTNKGYIKRLPASTYRSQRRGGRGIQGMGT-EDDFVEHLLTTSTHDTILFFTNKGKVYRSKGYEIPEFGRTAKGLPIINLLEVDQ-E
WVNAIIPVQ---DDWFLFFTTKQGISKRSPLSSFSN-RNNGLIALGLRENDELISVK-TDG-RDIIIGTKNGLLIRFPE--VRSMGRTATGVKGISLS--
GDVVGMDILEEKDDILIVTKKGYGKRTGEEEYRIQSRGGKGIKTCNVS-DKNGELVSVQTVT--EDLMVITANGVIIRMDVGQISRLGRNTMGVKLIRLE
GDYVSTVAKVE-
>tr|Q2B0I1|Q2B0I1_9BACI DNA gyrase subunit A OS=Bacillus sp. NRRL B-14911 GN=gyrA PE=3 SV=1
DEDLIPRENIVITLTHNGYVKRLPVSTYRAQKRGGRGIQGMGT-EDDFVEHLITTSTHNTLLFFTNKGKVYRAKGYEIPEFSRTAKGIPIINLLGINK-E
WVNAVIPVE---DEWFLFFTTKEGISKRSPLTSFGN-RNNGLIALNLREGDELISVR-TDG-KEIIIGTKNGQLIRFPE--VRSMGRTATGVKGITLD--
DDVVGMEVLEENSEILMVTKKGYGKRTPEMEYRVQGRGGKGIKTGNIT-DKNGTIVAVKVVTE-EDIMLITTGGVLIRMAVGDISTMGRNTQGVRLIRIN
SGYVATVAKVE-
>tr|W0FNS9|W0FNS9_9BACT DNA topoisomerase (ATP-hydrolyzing) OS=uncultured bacterium Contig54 PE=4 SV=1
DST-PVPEDAVVLFTGSGYLKRVSPVLLKRSPLPS------PA-ED-SARFLLETTTAETLYIFTDQGNCYPVPVGRLAEK-PRDRGQLLSGVL-ML--E
K--FMLTADA-KSMPDFLFVTRNGMIKRTAAADYDV-S--KYPALSLK--DSLLD---P---ADILLVTRGGMSI------VPVQGRVATGVRAMAVES-
-GVSFFRQLSAGDEVILFSERGWAKRIPQ-DFE-QNRSGKGVRCF---NKNNGRI-GVCVIP-PSSLLVTQLRSP-MT-RL-EILL-NR---GMPYVMAI
D-IVTGIITLP-
>tr|A0A0M6WLK8|A0A0M6WLK8_9FIRM DNA gyrase subunit A OS=Roseburia faecis GN=gyrA PE=3 SV=1
MEDLIPETNTVITMTKVGYIKRMGTDNFKSQHRGGKGIKGMET-QDDYIVEMLMTTSHHYLMFFTNMGRVYRIKAYEIPEASRTSRGTAIINIIPLQP-E
KITAMIPIK---KDKYLFMATKNGIVKKTSVLDYEN-RKTGLAAISLRDDDELIEVK-TGD-EEILLFTRYGQCIRFKE--VRATGRTTMGVIGMNLT--
-GVIAMQMASQGESVMIVSENGLGKCTRINEFTTQNRGGKGVKCYKIT-E-SGNLIGVKSVVD-DELMLITTEGIIIRIRVNDTALLGRVTSGVKLIDLK
-GTVASIARVV-
>tr|W0FQ07|W0FQ07_9BACT DNA topoisomerase (ATP-hydrolyzing) OS=uncultured bacterium Contig21 PE=4 SV=1
DNT-PVPEDTVVIYTEGGYLKRVSPVLLKRSPLPT------PE-AE-SARWLLPTTTAENLYIFTDLGNCYPVKVGTMAEK-PKDRGQLLSGVL-KI--E
Q--LMLTCDA-SSLPDFLFVTRNGMIKRTAAADYDV-S--KYPTLSLK--DSLLA---A---GDLLLITRGGMSI------VPVQGRIATGVKAMGVES-
-GVFWVGQLEETDEIILFSERGWAKRIPQ-DFE-QNRAGKGVRCF---NKNNGKI-GVCRIS-PCDLLIGQVRSP-LS-KL-DILL-NR---GMPYVMAI
D-IVTGVTPVA-
>tr|N9XW89|N9XW89_9CLOT DNA gyrase subunit A OS=Clostridium colicanis 209318 GN=gyrA PE=3 SV=1
VEDLIQEQEIVITLTHSGYIKRISSDVYSAQKRGGKGIQAMST-EDDFVEHAMVTSTHSDILFFTNRGRVYKLRGYQIPDG-RTAKGTNIINLISIEA-E
KIETVLTVN---KGGFLFMGTKNGIVKKTKLEEFKN-RKNGLNAITLRDGDELLKVK-TKG-ADIIVVTQNGMAVKFNE--VRPMGRTASGVKAITLK--
-DAVCMDIATP-EELLVVSENGYGKRTPTSEYKVQNRGGKGLITYKIT-E-TGKVIGATVCKD-DELMLINSNGIAIRINVSDISITGRAAMGVKLMRTL
EE-VVTIAKIT-
>sp|P94605|GYRA_CLOAB DNA gyrase subunit A OS=Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787) GN=gyrA PE=3 
IEDLIQEENVVITLTHAGYIKRINADTYTSQKRGGRGIQAMTT-EDDFVENIFITSTHNNILFFTNKGRMYKLKAYQIPEG-RAAKGTNVVNLLQLDP-E
KIQAVISIK---EESFLVMCTKKGIIKKTVVGMYKN-RKSGLIAINLNDDDELVSVR-TKG-DDIIIVTNKGLAIRFNE--VRPLGRNALGVKGITLK--
-DVVGMEVPNQ-SDVLVVSENGFGKRTHVGEYKCQHRGGKGLITYKVS-D-TGKLVGVRMVEG-DELMLINNLGIAIRINVSDISTTSRNAMGVTLMRNN
DE-VLALAKIN-
>tr|B1BI52|B1BI52_CLOPF DNA gyrase subunit A OS=Clostridium perfringens C str. JGS1495 GN=gyrA PE=3 SV=1
IEDLIQEEDVVITLTHTGYIKRISSDVYSAQKRGGKGIQAMTT-EDDFVENVLVTSTHSNLLFFTTKGKVYKIKAYEVPDG-RTAKGTNLVNILPLEA-E
KIQTVLSFK---EDGYLFMGTKLGIVKKTPLKDFKN-RKNGLIALNLREGDELLRAK-TYG-ADIIFVTQDGNAIRFNE--VRPMGRTASGVKAISLR--
-GAVCMDIAVE-EKLLVVSENGYGKRTNLDEYKVQNRGGIGLITYKVS-D-TGKVVGATVCKD-DELMLINNQGVAIRINVSDISVTSRSAMGVKLMRTL
DE-VVTIAKIS-
>tr|U2NHN0|U2NHN0_9CLOT DNA gyrase subunit A OS=Clostridium intestinale URNW GN=gyrA PE=3 SV=1
LEDLIQEEDIVITLTHSGYVKRIAADTYSAQKRGGKGIQAMTT-EDDFVDHVVVTSTHSDVLFFTNRGRVYKVRAYEIPDG-RSAKGTNLVNIIPIEQ-E
RVETVLSIK---LEGYLFMATKNGIVKKTPLSEFKN-RKNGLIALNLRDEDELLKVK-TFG-AKIIIVTQDGYAIKFSE--VRPMGRTASGVKAISLR--
-NAVCMDIATD-EELLVISENGFGKRTPLTEYKTQNRGGVGLITYKVA-E-TGKLVGASVCKD-DEMMLINTSGVAIRINVSDISITSRSAMGVTLMRTL
EE-VVAVAKIS-
>tr|A0A0F3FQ28|A0A0F3FQ28_9CLOT DNA gyrase subunit A OS=Clostridium baratii GN=gyrA PE=3 SV=1
VEDLIQEKEIVITLTHSGYIKRISSDVYSAQKRGGKGIQAMST-EDDFVEHVMVTSTHSDILFFTNRGRVYKLRGYQIPEG-RAAKGTNVINLIAIEP-E
RIETVLTVN---ENGYLFMGTKNGIVKKTNLNEFKN-RKNGLIAINLREGDELLKVK-TRG-ANIIMVTQNGLAIKFNE--VRPMGRTASGVKAISLS--
-DAVCMDIAVD-EDLLVVSENGFGKRTPISEYKVQNRGGKGLLTYKIN-D-TGKLIGATMCKE-DELMLINNSGVAIRINIEDVSVTGRATMGVKLMRTL
EE-VVTITKIA-
>tr|R5QHP5|R5QHP5_9FIRM DNA gyrase subunit A OS=Firmicutes bacterium CAG:194 GN=gyrA PE=3 SV=1
MEDMIPRENTVIAMTSLGYIKRMTVDNFRAQNRGGKGIKGMQT-EDDYIEDLLMMHTHYYIMFFTNFGRVYRMKGYEIPEAGRTARGTAIINLLQLNP-E
KVNAVIPIPL--TGKNLFMVTKNGIVKKTPIDEFDH-RKNGLAAINLRDDDELIEVK-TDK-TEIFLVTKNGMCIRFKE--VRATGRTSMGVIGMNLT--
-QIIGMQLDHQGDSLLIVSEKGMGKRTYLDEFNVQKRGGKGVKCYKIT-D-TGYVVGVKAVND-HEIMMITTEGIIIQLRMEDVSTLGRITSGVKMINLD
N-KVAKIAKVR-
>tr|D6TF17|D6TF17_9CHLR DNA gyrase subunit A OS=Ktedonobacter racemifer DSM 44963 GN=gyrA PE=3 SV=1
DEDLIPNEEVVVTLTEKGYIKRLPSGTYRAQRRGGRGVTGMAT-EDDTVRHLLVPHTHDSLLFFTDRGRVFQLRVYELPDS-RTARGEHLINLISIEQRE
RVTAIVYVP-G--HDFLVVATKKGEVKKTAMSDFEVVRRSGLIAMNLEDDDELIGAKLVGPEADVLLITLHGHAIRFG---LRSASRTSGGVRGIRLT--
-TVVSLNAVIPGGELLVVTEHGYGKRTPIDEYP-YNRGGSGVLTSKVTE-KTGKVASARMTE-DNDLMLISASGVVIRTDVSLVR-AGRATQGVTLMNLA
-DKVVAVAVAN-
>tr|D1C4I8|D1C4I8_SPHTD DNA gyrase subunit A OS=Sphaerobacter thermophilus (strain DSM 20745 / S 6022) GN=gyrA PE=3 SV=1
DEDLIPDVSVLVMITNRGYVKRIADGTYRQQHRGGRGVTGMTL-EEDGVHRIVAARTHDSLLFFTDRGRVFQLKVWELPD-GRTARGIPVINLIGIEPGE
TITALLPVR-FS-ARYLFMCTRNGRVKRTRLDQFASVRSSGLIAIGLEEGDELAWVRLTSGNDELILVTEQGQAIRFK---VRPMGRPAAGVIGIRME--
-RVIAAEVVQ-DQDLLVVSANGYGKRTALSEFRVQGRGGQGVTAMKITE-RNGPVAAARVVT-TDSIMLVSLRGMVIRVPAEQISR-GRMTQGVSIMRLQ
EQQVASVTVIR-
>tr|K7S668|K7S668_9HELI DNA gyrase subunit A OS=Candidatus Sulfuricurvum sp. RIFRC-1 GN=gyrA PE=3 SV=1
IEDLIPNEPMVVTISHRGYIKRVPLVAYEKQIRGGKGIAVT-T-DDDFIEKFYTCNTHDTLMFVTDRGQLHWLKVYKIPEGSRTAKGKAVVNLINLEADE
KIRSIIPTT---ESKSLVFFTQNGVVKRTALSEFSNVRSNGVRAIVLDDDDALITAH----TKYLFIVTKYAQCIKFE---TRDQGRSTRGVRGIKFKD-
-DVVDANIIKSEEEILMVSEKGIGKRTTAEEYRLTNRAGTGVIAMKLN--KTGTTVVGCLVD-TMDMMALTKAGKMIRVDMQTIAKSGRNTSGVYIIK--
--DVASISRCP-
>tr|A0A0A8H5A2|A0A0A8H5A2_9PROT DNA gyrase subunit A OS=Campylobacter insulaenigrae NCTC 12927 GN=gyrA PE=3 SV=1
IEDLIPNENMVVTITHRGYIKRVPSKQYEKQKRGGKGVAVT-T-DDDFIENFFTANTHDTLMFVTDRGQLYWLKVYKIPEGSRTAKGKAVVNLINLQVDE
KIMAIIPTT---ENKSLCFFTKNGIIKRTNLSEYQNIRSVGVKAINLDENDELVTAIVTNDGKMLFAVTKKGMCIKFL---VREIGRVSRGVTAIKFKK-
-DLVGAVVIENEQEILSISAKGIGKRTNAGEYRLQSRGGKGVICMKLT--KTKDLIS-VVVD-SMDLMALTSSGKMIRVDMQSIRKAGRNTSGVIVVNVE
--EVVSIAKCP-
>tr|A4BM47|A4BM47_9GAMM DNA gyrase subunit A OS=Nitrococcus mobilis Nb-231 GN=gyrA PE=3 SV=1
LEDLIQPEDVVVTLSHGGYAKSQPLDSYQAQHRGGKGAATK-MKDEDFIDQLFLANTHDTLLCFSSHGKCYWLKVYELPHGSRGSRGKPIVNLLPLD-AE
RISAVVSIKEFDDQHFVFMATRKGTVKKTPLSDFSRPRSSGIIAVNLQEDDWLVNVGITDGEREIMLLTDAGKAIRFPEDAVRPMGRTAGGVRGIQLGTQ
S-VIQLLILG-EGDILTATENGYGKRTPVAEYPRRSRGGRGVISIQTSE-RNGNVVGAAQVTEEDEIMLITNAGTLVRIPVAEISIVSRNTQGVKLIALG
GERLAGVARIE-
>tr|A0A0R1WP63|A0A0R1WP63_9LACO DNA gyrase subunit A OS=Lactobacillus hayakitensis DSM 18933 = JCM 14209 GN=FC40_GL001549 PE=4 SV=1
DEDLIEEENVVVTLTHNGYIKRLPTSDFKAQNRGGRGVQGMGV-DDDFIEHLLTTSTHDELLFFTNTGKVYRMKGYEIPEYGRTAKGIPMINLLDI-SDE
KIQTVINVPQ-DKEMYLFFITRQGVVKRTAVSEFGN-RKNGLKAVTLHEDDELINVL-TDN-KNIIIATHQGYAVSFAE--IRSMGRSAAGVRGVRLR--
-NVVGSAILEADDQVFVISEKGYGKKTLASEYPIKGRGGKGIKTSNIT-E-NGPLAGMTTVTN-EDIMVITNKGVMIRFGADKVSQTGRATLGVRLINLD
D-IVSTMTKVE-
>tr|A0A0R2AIE4|A0A0R2AIE4_9LACO Dna gyrase subunit a OS=Lactobacillus agilis DSM 20509 GN=FC14_GL002000 PE=4 SV=1
DEDLIEEESVAITVTHNGYIKRIPTSDFKQQNRGGRGVQGMGV-DDDFIEQLITSSTHDELLFFTNLGKVYSMKGYEIPEYGRAAKGIPVINLLNI-EDE
KITTVINVPV-PDDLALFFTTKLGVVKRTSVAEFTN-RKNGLKALNLHEGDELINVV-VKA-ANVIIGTHQGYSVSFAV--VRLMGRAAAGVRGIRLR--
-AVVGSDVLAADSKVFVISEKGYGKQTLASEYPIKGRGGKGIKTANIG-T-NGPLVGLTTVKD-EDIMVITDKGVMIRFNIETVSQTGRATMGVHLINLD
D-VVSTMAKVE-
>tr|A0A0R1TFF5|A0A0R1TFF5_9LACO DNA gyrase subunit A OS=Lactobacillus equi DSM 15833 = JCM 10991 GN=FC36_GL000777 PE=4 SV=1
DEDLIEEESVVIALTHNGYIKRVPTSDFKAQKRGGRGVQGMGV-DDDFIEHLLTTSTHDMLLFFTNKGKVYSMKGYEIPEYGRTAKGIPVINLVEF-EGE
KISTVLNVTV--NKLRLFFTTKNGVVKQTSVADFTN-RKNGLKALTLRDNDELINVS-LDQ-STIIIGTHQGYAASFAS--VRVMGRAASGVRGIKLR--
-DVVGTGVLTSDSKVLVISENGYGKLTKASEYPVKGRGGKGVKTSTIT-S-NGPLVGFTTIND-EDIMVITDKGVMIRFDAQNVSEVGRSAMGVRLMNLK
G-KVSTMTVVA-
>tr|F5VDS3|F5VDS3_9LACO DNA gyrase subunit A OS=Lactobacillus salivarius NIAS840 GN=gyrA PE=3 SV=1
DEDLIEEENVVVTLTHNGYIKRLPTSDFKAQNRGGRGVQGMGV-DDDFIEHLLTTSTHDELLFFTNVGKVYRMKAYEIPEYGRTAKGIPVINLLDI-SDE
KIQTVINIPV-DKEMYLFFITRQGTVKRTSVSEFGN-RKNGLKAITLRDGDELINVL-TDD-KNIIIGTHQGYAVSFDE--IRSMGRSAAGVRGIRLR--
-NVIGSAILEPESKVFVISENGYGKQTAASEYPIKGRGGKGIKTTNIT-E-NGPLAGLTTVND-EDIMVITDKGVMIRFKISDVSETGRATLGVRLINLG
D-IVSTMTKVE-
>tr|F4XGH3|F4XGH3_9FIRM DNA gyrase subunit A OS=Ruminococcaceae bacterium D16 GN=gyrA PE=3 SV=1
IEDLIEEEQCVFTLTQAGYIKRTPVSEYAAQSKGGQGRKGITT-DEDCVVDVFTASTHDYLFFFTDTGKVYRKKGYQIPEG-KTAKGTNIVNILQVEQGE
KVQTMIHTR-L-PDLYLVMVTRNGTVKRLPVTALKNIRNSGIRALRLEEGDQLISVRETDGTKKILIATHDGMAVCFD---VRPMGRDAVGVRGIRLR--
-YVVSAARATAGRTVLTITEKGYGKRTPVEDYR-TNRGGIGIKNYAVTE-KTGKIVGIKVVD-SEDLLLVTQAGILIRTHVDAIR-AGRATQGVIVMRFK
-EKVISLALAE-
>tr|V2YII1|V2YII1_9FIRM DNA gyrase subunit A OS=Firmicutes bacterium ASF500 GN=gyrA PE=3 SV=1
IEDLIEEEQCVFTLTQAGYIKRTPVSEYAAQSKGGMGKKGITT-EEDYVVDVFTASTHDYILFFTDTGKVYRKKGYQIPEG-KTAKGTNIINILQVEQGE
RVQAMLHYR-H-EELYLFMVTRNGTVKRLPVQTLKNLRNNGIRALRLDEGDQLVSVRETDGSKKILIATHDGMAVCFD---VRPMGRDAVGVRGIRLR--
-YVVGAARALEGKTVLSITEKGFGKRTPVEEYR-TNRGGLGIKNYMVTD-KTGPIVGVKVVD-SEDLLVVTQAGILIRTHVDAIK-CGRSTQGVIVMRFK
-EKVISLALAE-
>tr|R5RZW4|R5RZW4_9FIRM DNA gyrase subunit A OS=Firmicutes bacterium CAG:129 GN=gyrA PE=3 SV=1
IEDLIEEEQCVFTLTQNGYIKRTGVSEYAAQGKGGMGKKGITT-EEDTVVDVFTASTHDYILFFTDTGKVYRKKGYQIPE-GKAAKGTNIVNIIQVETGE
RVQAMLHFR-KDEKLYLTMVTRNGTVKRLPVETLKNLRSNGIRALSLDEGDELVAVRETDGSQRILIATHDGMACVFD---VRAMGRTAVGVRGIRLR--
-YVVGTARA--GKQVLSITENGFGKKTPVEEYRITNRGGLGIKNYSVTE-KTGGVVGVKVVD-SEDLLLVTRAGILIRTPVADIRS-GRATQGVIVMRFK
EGQVISMALAE-
>tr|U2RZU8|U2RZU8_9FIRM DNA gyrase subunit A OS=Oscillibacter sp. KLE 1745 GN=gyrA PE=3 SV=1
IEDLIEEEQCVFTLTQAGYIKRTPASEYTAQSKGGMGKKGITT-EEDYVVDVFTASTHDYILFFTDTGKVYRKKGYQIPEG-KAAKGTNIVNILQVEQGE
RIQAMIHTR-I-DGRFLFMVTRNGTVKRLPANTLKNLRNNGIRALRMEEGDQLIAVRETDGSQKILIATHDGMAVCFD---VRPMGRDAVGVRGIRLR--
-YVVGAARAKANHAVLAITENGYGKQTPVEDYR-TNRGGLGIKNYMVTD-KTGPVVGIKVVD-TEDLLLVTQAGILIRTPVDSIR-AGRATQGVIVMRFK
-EHVISLALTD-
>tr|G4KQC3|G4KQC3_OSCVS DNA gyrase subunit A OS=Oscillibacter valericigenes (strain DSM 18026 / NBRC 101213 / Sjm18-20) GN=gyrA PE=3 SV=1
IEDLIEEEQCVFTLTEAGYIKRTPVSEYTAQSKGGMGKKGITT-DEDVVVDVFTASTHDYILFFTDTGKVYRKKGYQILEG-KTAKGTNLINILQIEQGE
RVQAMVHTR-I-DGRFLFMVTRNGTVKRLPASTLKNLRNNGIRALRMDEGDQLITVRETDGTKKILIATHDGQAVCFQ---VRPMGRDAMGVRGIRLR--
-YVVAAARATEGKTVLSITEKGYGKRTPVEDYR-TNRGGLGIKNYMVTE-KTGPVVGVKVVD-SEDLLLVTQSGIMIRTPVESIR-AGRATQGVIVMRFK
-DQVISMALTD-
>tr|A6NQF3|A6NQF3_9FIRM DNA gyrase subunit A OS=Pseudoflavonifractor capillosus ATCC 29799 GN=gyrA PE=3 SV=1
IEDLIEEEECVFTLTAGGYIKRLPASTYKTQRRGGKGITAMAT-EEDYVDTVFTASTHDFILFFTNKGRVHRKKGYQIPE-GRMAKGTNLVNILPVESGE
KVTAMIHLR-FE-DRYLAMVTRNGTVKRIQLSAINTARKAGIRCITLDEGDELIAVRETDGDQAILIATHDGMSICFK---VRCMGRDACGVRGIKLR--
-YVIGAARA--GHQVLMVTENGYGKRTDMDEYIRQNRGGYGLKGYNVTE-KTGPVVGVKVVS-ADDILVINDAGVIIRMAVSGIST-GRAAQGVKLMNLD
EGKVISFARTD-
>tr|R5FJG2|R5FJG2_9CLOT DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium bolteae CAG:59 GN=BN723_00558 PE=4 SV=1
MEDLIPDEDTIIAMTHLGYIKRMDVDNFRSQNRGGKGIKGMQT-EEDYIEDLLMTTNHHYMMFFTNTGRVYRLKAYEIPEG-RTARGTAIINLLQLMPEE
KITAIIPMR-F--DKYLFMATRNGMVKKTPMVEYEHVRKNGLQAIVLRDGDELIEVKATDNSQDILLVTRKGMCIRFN---VRVTGRVSMGVIGMRFE--
-EVIGMQMQSQGDSLLVVSENGMGKRTMITEFS-QNRGGKGVICYKCTD-KTGYLVGAKLVN-GREIMIITTEGIIIRMTVDDIS-IGRNTSGVKLMSID
-DKVASIAKVR-
>tr|C0CSZ7|C0CSZ7_9FIRM DNA gyrase subunit A OS=[Clostridium asparagiforme] DSM 15981 GN=gyrA PE=3 SV=1
MEDLIPDEDTVIAMTHLGYIKRMDVDNFRSQNRGGKGIKGMQT-EEDYIEDLLMTTNHHYVMCFTNTGRVYRLKAYEIPEAGRTARGTAIVNLLQLQP-E
KITAIIPMR---EDKYLFMATKGGMVKKTPMCEYEN-RKNGLQAIVLRENDELIEVK-TDN-EDIFLITKNGMCIRFHE--VRVTGRVSMGVIGMRFE--
-GVIGMQMASQGDSLLVVSENGMGKRTVINEFSAQNRGGKGVICYKIT-E-TGCLIGAKLVDG-REIMMITTEGIVIRMVVDDISVIGRNTSGVKLMAID
DDKVASIAKVR-
>tr|L1QI38|L1QI38_9CLOT DNA gyrase subunit A OS=Clostridium celatum DSM 1785 GN=gyrA PE=3 SV=1
IEDLIQEEETVVTLTHSGYIKRISADTYSAQRRGGRGIQAMAT-EDDFVEHVLVTSTHSDVLFFTNRGRVYKKRAYEIPDG-RTAKGTNIINLIQIEQ-E
RIETVLTVR---AEGYLFMATKQGLVKKTPLSEFKN-RKSGLIAINLREGDELLKVK-TRG-ADIIIVSQDGNAIKFNE--VRPMGRTASGVKSMNLR--
-DAVCMDIAVD-EDLLVISENGFGKRTPLTEYKRQNRGGVGLITYKIS-E-TGKVIGATVCKE-DELMLINTSGIAIRINVSDISVTSRSAMGVTLMRTS
EE-IVAIAKIA-
>tr|R6LJ40|R6LJ40_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:265 GN=gyrA PE=3 SV=1
IEDLIQEEDVVITLTNSGYIKRISADTYSAQRRGGRGIQAMTT-EDDFVENVLITSTHSDVLFFTNKGRVYKKRAYEIPDG-RTAKGTNIINLIPIEQ-E
RIETVLTIA---REGYLFMATKKGLVKKTHLSEFKN-RKNGLIAISLREGDELLKVK-TRG-ADIVIVSEHGNAIKFNE--VRAMGRTAAGVKSMNLR--
-DAVCMDIAVD-EDLLVISENGFGKRTPLVEYKRQNRGGVGLITYKIS-E-TGKVVGATVCKE-DELMLINTSGVAIRINVSDVSVTSRATMGVRLMRTS
EE-IAAIAKIS-
>tr|R5QTS7|R5QTS7_9FIRM DNA gyrase subunit A OS=Ruminococcus torques CAG:61 GN=gyrA PE=3 SV=1
MEDLIPRENVVITVTNMGYIKRMSMDTFKSQNRGGKGIKGMQT-EEDFIRELFVTTSHHYIMFFTNKGRVYRLKAYEIPEAGRTARGTAVINLLQLMP-E
KITATIPIK---DGKYLFMATKKGLVKKTPIQDYMN-RKTGLAAISLREDDLLIEVK-TDN-QDILLVTKYGQCIRFNE--VRSTGRVSMGVRGMNLS--
-NIIGMQMSSQGKDMLIVSEKGMGKRTSMEEFTKQNRGGKGVKCYKIT-E-TGNVVGMKAVDE-SEIMIINTEGIVIRMKCSDISQYGRITSGVKLINLP
-KKVASVAKVR-
>tr|R5RVF8|R5RVF8_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:122 GN=gyrA PE=3 SV=1
MEDLIPNENTVITMTKLGYIKRMSVDNFKSQHRGGKGIKGMQT-DDDYIENMLMTTTHHYIMFFTNKGRMYRLKVYQIPECGRTARGTAIINLIQLMP-E
KITAVITLR---ENKYLFMATKKGIVKKTSIMEYAN-RKSGLQAINLRDDDDLIEVK-TDN-KDIFLVTKHGQCIRFDE--VRTTGRVSMGVIGMNLS--
-DVVAMQLNTQGTHMLIVSEYGMGKRTDIDEFTVQHRGGKGIKCYKIT-E-TGNVVAAKAVND-TEVMIINTEGIIIQLMVSEVSVLGRITSGVKMIEMD
EEVVASMTRVR-
>tr|F0Z5R0|F0Z5R0_9CLOT DNA gyrase subunit A OS=Clostridium sp. D5 GN=gyrA PE=3 SV=1
MEDLIPRENVVITMTKLGYIKRMTVDTFKSQNRGGKGIKGMQT-DEDYIKELFITSTHHYIMFFTNTGRVYRIKGYEIPEASRTARGTAIINILQLMP-E
KITAMIPIK---DGKFLFMATEKGLVKKTPITDYAN-RKTGLAAITLREDDRLIEVK-TDN-EDIVLVTKYGQCIRFSE--VRATGRTSMGVRGMNLS--
-RVIAMQMSTQGSDLLIVSDKGMGKRTNLDEFTTQNRGGKGVKCYKIT-E-TGNVVGMKAVND-SEIMIINTEGIIIRMQCSDISVLGRVTSGVKLINLA
G-TVASVAKVR-
>tr|R9JLL1|R9JLL1_9FIRM DNA gyrase subunit A OS=Lachnospiraceae bacterium M18-1 GN=gyrA PE=3 SV=1
MEDMIPKEDVVVTMTKLGYIKRMTIDNFKNQNRGGKGIKGMQK-DDDFIQELFITFTHNYIMFFTNKGRVYRMKAYEIPEAGRTSRGTAIINLLQLMP-E
KITAMIPIK---DNQYLFMATENGLVKKTPLYEYNN-RKKGLAAITLREDDNLIEVK-TDN-KEILLVTKYGQCIRFDE--VRSTGRTSMGVRGINLS--
-GVIGMQVHTQGECLLIVSENGIGKRTIMGEFTIQNRGGKGVKCYKIT-E-TGDVIGMKAVSD-DEIMMINSEGIIIRMSCADISKLGRITSGVKLINLK
E-KVVSLAKVR-
>tr|R5U687|R5U687_9FIRM DNA gyrase subunit A OS=Ruminococcus gnavus CAG:126 GN=gyrA PE=3 SV=1
MEDLIPRENVVITMTKMGYIKRMSMDTFKSQNRGGKGIKGMQI-DDDYIKELFITTTHHYIMFFTNTGRVYRLKGYEIPEASRTARGTAIINLLQLMP-E
KITAMIPIR---DGQYLLMATEKGLVKKTPIKDYAN-RKTGLAAIVLREDDKLIEVK-TDD-QDVILVTKYGMCIRFSE--VRPTGRVSMGVRGMNLG--
-HVIGMQISDQGKYLLIASEKGMGKLTDMDEFTRQNRGGKGVKCYKIT-E-TGDVVGMKAVDD-SEIMMINTEGIVIRMKCSDISVYGRITSGVKLINLP
N-KVASIAKVR-
>tr|R6E942|R6E942_9FIRM DNA gyrase subunit A OS=Lachnospiraceae bacterium CAG:215 GN=gyrA PE=3 SV=1
MEDMIPKEDVVITMTKMGYIKRMTMDNFKSQNRGGKGIKGMQK-DEDYIQELFVTSTHNYIMFFTNTGRVYRMKAYEIPESGRTSRGTAIINLLQLMP-E
KITAMIPIK---DDQYLFMATEQGLVKKTLLREYVN-RKKGLAAITLRDDDQLIEVK-TDN-KDILLVTKYGQCIRFDV--VRATGRTSMGVRGINLD--
-RVIGMQVNTQGDCLLVVSEKGMGKRTAMGEFTNQNRGGKGVKCYKIT-E-TGNVIGMKAVND-DEIMMINSEGIIIRMACDTISKLGRITSGVKLINLK
N-TVVSVAKVR-
>tr|R6DUZ8|R6DUZ8_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:230 GN=gyrA PE=3 SV=1
MEDLIPNENTIITMTKLGYIKRMTLDNFKSQHRGGKGIKGMQT-EDDYIEDLFMATTHHYLMFFTNKGRVYRLKAYEIPEASRTARGTAIINLLQLLP-E
KITAVIPIR---DQKYLFMATKKGIVKKTSIVEYAN-RKTGLQAISLRDEDELIEVK-TNK-KDIILITKHGQCIRFNE--VRPTGRTSMGVIGMNLS--
-DLIGMQLNTQGDCLMIVSEYGMGKKTDINEFGVQHRGGKGVKCYKIT-D-TGNVVNAKAVND-NEVMLITTEGIIIQLKVSEISTLGRITSGVKLIDLD
EDVVASMAKVR-
>tr|B5CNG5|B5CNG5_9FIRM DNA gyrase subunit A OS=Ruminococcus lactaris ATCC 29176 GN=gyrA PE=3 SV=1
MEDLIPRENVVITMTKLGYIKRMTMDTFKSQNRGGKGIKGMQT-EDDYIRELFVTTSHHYIMFFTNTGRVYRMKAYEIPEAGRTARGTAIINLLQLMP-E
KITAIIPLR---EGKYLFMATEKGLVKKTPIQDYAN-RKTGLAAIALREDDRLIEVK-TDN-EDILLVTRDGMCIRFNE--VRSTGRVSMGVRGMNLT--
-NVIGMQTASQGTDLLIVSEKGMGKRTNMDEFTRQNRGGKGVKCYKIT-E-TGNVVGMKAVDD-SEIMIINTEGIIIRMKCSDISVYGRITSGVKLINLK
K-KVASVAKVR-
>tr|R5GBQ4|R5GBQ4_9FIRM DNA gyrase subunit A OS=Eubacterium sp. CAG:146 GN=gyrA PE=3 SV=1
DEALIPRKDAIITFSKLGYIKRMTPDNFHSQNRGGKGIRGMNV-DEDHIEDLFMTSTHNYIMFFTNKGRVYRLKGYEIPESGRTARGVNIINLLQLQP-E
KITAIIPLL---KQHYLVMATRNGLVKKTGFDEYKN-RKNGLAAISLREGDELIEVK-TDE-EDIFLVSKEGQCIRFKL--VRETGRVSMGVIGMNLG--
-TVVGMQIRSEGDDLLIVSEKGMGKRTPLDEFTVQHRGGKGLRCYKIT-D-TGYVVGVKTIKE-EEIMLITTEGIVIRMKSDSISVIGRNTSGVKLINID
ESKVASVAKVR-
>tr|A7VDH0|A7VDH0_9CLOT DNA gyrase subunit A OS=Clostridium sp. L2-50 GN=gyrA PE=3 SV=1
DEELIERENIVITMTKLGYIKRMPEDIFKAQNRGGKGIRGMQT-DEDYIESMIVTTTHNYLMFFTNTGRVYRLKGYEIPEAGRTARGVAIVNLLQLQA-E
KITAVIPLK---DGKYLFMATRNGMVKKTDISEYQN-RKTGLTAIVLRDNDELIEVK-TNG-DDIFLITKKGMTIRFNE--VRQTGRTSMGVKGIHLG--
-DVISMQMSSQGEKILLVTENGMGKRTLISEFNVQNRGGKGVKCYKIT-D-TGDLVGAKIVTE-NDIMIITTEGIIIRTSCEGISTLGRVTSGVKVINLN
DNKVASMTEVQ-
>tr|R5NSC5|R5NSC5_9FIRM DNA gyrase subunit A OS=Eubacterium sp. CAG:603 GN=gyrA PE=3 SV=1
VEDLIPNENTVIARTNLGYIKRMTVDNFKSQNRGGKGIKGMQT-DDDYIVDLLMTSTHHYLMFLTNMGKAYRLKAYQIPEAGRTARGTAIINLMQLQP-E
KISAVIPVK---DSKFLFMTTKNGIVKKTPLIDFAN-RKTGLQAINLKDDDELIEVK-TNN-RDIFLVTKYGMCIRFNE--VRKTGRTSMGVIGMNLE--
-GIVGMQMNNQGDSLLIVSENGLGKRTSIDEFKLQKRGGKGVRCYRIN-D-TGYVVGVKAVND-HEIMMITNEGIIIQFKVNTVSEIGRNTFGVKLINID
DNKVAKIAKVR-
>tr|R5NP84|R5NP84_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:127 GN=gyrA PE=3 SV=1
VEDLIPKENVVIAMTKLGYVKRMTINNFKSQNRGGKGIKGMQT-EDDFIENLFMTTTHHYIMFFTNQGRVYRLKTYEIPESGRTARGTAIVNLLQLQP-E
VITAVIPIR---EGRYLIMATKNGMIKKTKITEYAN-RKSGLAAITLKEGDELIEVK-TNN-KDIILITKQGMCIRFNE--VRSTGRTSMGVIGMSVA--
-DVIGMQLDTQGEALLIVSENGLGKRTLVEEFTPQHRGGKGVKCYKIT-D-SGTVVGFKAVND-NEIMLITNQGIVIRLLCKDISILGRITTGVKLINMD
EDTVASIAKVR-
>tr|R6V312|R6V312_9FIRM DNA gyrase subunit A OS=Roseburia sp. CAG:380 GN=gyrA PE=3 SV=1
MEDLIPQENTIITMTSLGYVKRMSVDNFKSQHRGGKGIRGMQT-DEDYIADMLMTTTHHYLMFFTNKGRVYRLKAYEIPESSRTARGTAIINLLQLTP-E
KINAVIPIR---ENRYLFMATKKGIVKKTSIKDFAN-RKTGLQAINLRDDDELIEVK-TNC-KDIILVTKHGQCIRFHE--VRPTGRATMGVIGMNLT--
-DVVGMQLDTQGDYLMLVSEYGMGKRTRIEEFTPQHRGGKGIKCYKIT-E-TGNVVSVKAVNE-NEIMLITTEGIIIQMRVDEISVLGRITSGVKLIDLD
NDVVATMAKVR-
>tr|A6ER35|A6ER35_9BACT DNA gyrase subunit A OS=unidentified eubacterium SCB49 GN=gyrA PE=3 SV=1
ITDLIPDEQVVLTISHAGYIKRTSLTEYKTQNRGGVGQKASAT-NEDFLEHLFVGTNHQYMLFFTQKGKCFWMRVFEIPEGSKTSKGRAIQNLINIEPDD
KVMAFICTQK--NSRYVIMATKKGQVKKTPLEQYSR-RTNGINAITIKDDDELLEAKLTRGDSQVMLAVKSGKAIRFE---TRPMGRNASGVRGIRLAD-
-DVVGMIAINDESEILVVSDKGYGKRSSIE-YRITNRGGKGVKTINVTE-KTGQLVAIKNVI-SDDLMIINKSGIAIRMDVSSLRVMGRATQGVRLIKVR
-DSIAAVAKVM-
>tr|A0A0R2RZ30|A0A0R2RZ30_9FLAO DNA gyrase subunit A OS=Cryomorphaceae bacterium BACL21 MAG-121220-bin10 GN=ABR84_05665 PE=4 SV=1
ITDLIPDEQVVITISHAGYIKRTPLTEYKTQNRGGVGQKASST-NEDFLEHLFVGTNHQYMLFFTQKGKCFWMRVFEIPEGSKTSKGRAIQNLINIEQDD
KVKAFICTQK--NNHYLIMVTKMGQVKKTTLEQYSR-RTNGINAITIKDGDELLEVKLTTGDSQVMIAVRSGKAIRFE---TRPMGRGASGVRGITLGA-
-DVIGMIAVDGASDILVVTENGYGKRSSIE-YRITNRGGKGVKTINITD-KTGDLVAIKNVS-LDDLMIINKSGIAIRMAVEDLRVMGRATQGVRLIKVR
-DSIAAVAKVM-
>tr|F4B3A6|F4B3A6_DOKS4 DNA gyrase subunit A OS=Dokdonia sp. (strain 4H-3-7-5) GN=gyrA PE=3 SV=1
ITDLIPDKKVVITISNAGYIKRTSLTEYKTQNRGGVGTKASTT-NEDFLEHLFVGTNHQYMLFFTQKGKCFWMRVFEIPEGSKTSKGRAIQNLINIEQDD
EVKAFVCTGK--NNHFIIMATKKGQVKKTALEQYSR-RTNGINAITIKDDDELLSVKLTTGESQVMLALKSGKAIRFE---TRPMGRNASGVRGITLAD-
-DVIGMVSVNDESNILVVSEKGYGKRSSLE-YRITNRGGKGVKTISVTE-KTGELVAIKNVT-ADDLMIINKSGIAIRMEVASLRVMGRATQGVRLINLK
-NSIAAVAKVK-
>tr|I3YZ69|I3YZ69_AEQSU DNA gyrase subunit A OS=Aequorivita sublithincola (strain DSM 14238 / LMG 21431 / ACAM 643 / 9-3) GN=gyrA PE=3 SV=1
ITDLIADEQVVLTISHAGYIKRTSLSEYKTQHRGGVGQKASAT-NEDFLEHLFVGTNHQYMLFFTQKGKCFWMRVFEIPEGSRTSKGRAIQNLINIEPDD
KVMAFICTQK--NSHYVIMATKKGQVKKTPLEQYSR-RTNGINAITIREGDELLEAKLTTGNSQVMLAVRSGKAIRFE---TRSMGRNASGVRGIRLGE-
-DVIGMIAVNEDSDILVVSENGYGKRSSID-YRITNRGGKGVKTINITE-KTGKLVAMKNVT-DDDLMIINKSGIAIRMGVADLRVMGRATQGVRLIKVR
-DAIAAVAKAM-
>tr|A0A0D7W1S5|A0A0D7W1S5_9FLAO DNA gyrase subunit A OS=Tamlana nanhaiensis GN=gyrA PE=3 SV=1
IEDMIPNEKVVITISHAGYIKRTSLNEYKTQNRGGVGQKASTT-NEDFLEHLFVGTNHQYMLFFTQKGKCFWMRVYEIPEGSKTSKGRAIQNLINIEQDD
KVMAFICTQK--NSHYVIMATKNGQVKKTALEQYSR-RTNGINAITIKDNDELLEAKLTTGNSQVMLALRSGKAIRFE---TRPMGRGASGVRGITLAEN
-DVIGMVTVENEETVLVVTENGYGKRTFIDVYRITNRGGKGVKTISITE-KTGNLVAIKSVT-NDDLMIINKSGIAIRLAVENLRTMGRATQGVRLINLK
-NSIAAVAKVM-
>tr|G2EHR0|G2EHR0_9FLAO DNA gyrase subunit A OS=Bizionia argentinensis JUB59 GN=gyrA PE=3 SV=1
IEDMIPDEQVVITISHAGYIKRTSLTEYKTQNRGGVGQKASTT-NEDFLEHLFVGTNHQYMLFFTQKGKCFWMRVYEIPEGSKTSKGRAIQNLINIEQDD
KVKAFISTQK--NSHYVIMATKKGQVKKTSLEQYSR-RTNGINAITIREDDELLEAKLTTGNSQVMLALKSGKAIRFE---TRPMGRNASGVRGISLADK
-DVIGMIAVENEESVLVVSEKGYGKRTYIDVYRITNRGGKGVKTISITE-KTGHLVAIKSVS-DEDLMIINKSGIAIRMAVADLRVMGRATQGVKLINLK
-SSIAAVAKVM-
>tr|A0A084THP9|A0A084THP9_9FLAO DNA gyrase subunit A OS=Mangrovimonas yunxiaonensis GN=gyrA PE=3 SV=1
IEDMIPDEKVVITISHAGYIKRTPLSEYKTQNRGGVGQKASTT-NEDFLEDLFVGTNHQYMIFFTQKGKCFWMRVYEIPEGTKTSKGRAVQNLINIEQDD
KVKAFICTQK--NSHYVIMATKKGQVKKTSLEQYSR-RTNGINAITIKDGDELLEAKLTTGDSQVMLAVKSGKAIRFE---TRPMGRSASGVRGITLADK
-DVVGMITINDEETVLVVSENGYGKRTFIDIYRITNRGGKGVKTISVTE-KTGNLVAIKSVS-KDGLMIINKSGIAIRMDVADLRTMGRATQGVRLINLK
-SSIAAVAKVV-
>tr|A0A0R1W9Y0|A0A0R1W9Y0_9LACO DNA gyrase subunit A OS=Lactobacillus suebicus DSM 5007 = KCTC 3549 GN=FD16_GL002159 PE=4 SV=1
DEDLIEEENVIVSLTHNGYIKRLPVDEFKAQHRGGRGVQGMGV-DDDFIEQMISTSTHDRLLFFTSAGKVYSMKGYEVPEYGRTAKGIPVINLLGV-DDE
KISAVINVE--YSDKYLFFTTLHGTVKRTAVSEFTN-RSNGLKSITLKEDDELIGVS-IDD-QNMIIGTHLGYAVSFKA--VRSMGRSASGVRGIRLR--
-NVIGVDLLNENSNVFVISEHGFGKQTSASEYPIKGRGGKGIKTANVT-E-NGPLVGLTTVEE-EDIMLVTDKGVIIRFGIETVSQTGRATVGVHLIKMD
E-KVATMAKVD-
>tr|A0A0D1A9I3|A0A0D1A9I3_9LACO DNA gyrase subunit A OS=Lactobacillus wasatchensis GN=gyrA PE=3 SV=1
DEDLIEEENVIVSLTHNGYIKRLAVDEFKAQHRGGRGVQGMGV-DDDFIEQLISTSTHDRMLFFTNAGKVYSMKGYEVPEYGRSAKGIPVINLLGI-DDE
KISAVINVS--DHDKYLFFTTLHGTVKRTPVAAFEN-RSNGLKAITLKENDQLMGVS-IEE-QNMIIGTHLGYAVSFRG--VRSMGRSASGVRGIRLR--
-NVIGVDLLSADSHVFVISERGFGKQTPASAYPIKGRGGKGIKTANVT-E-NGPLVGLATVTA-EDIMLVTDKGVIIRFGIENVSETGRATLGVHLIKMD
D-HVATMTKVA-
>tr|A0A0R1RF55|A0A0R1RF55_9LACO DNA gyrase subunit A OS=Lactobacillus oligofermentans DSM 15707 = LMG 22743 GN=FC70_GL001300 PE=4 SV=1
DEDLIEEEDVIVSLTHNGYIKRLPVDEFKTQNRGGRGVQGMGV-DDDFIEQMISTSTHDMLLFFTNTGKVFSMKGYEIPEYGRTAKGIPIINLLGI-DEE
KISAVVNIA--NDDNFLFFTTLKGTVKRTPVSEFTH-RNNGLKSITLKEDDSLIGVS-ISE-QNMIIGTHLGYAVSFKG--VRSMGRSASGVRGIRLR--
-NVIGVDILEADSKVFIISEKGFGKQTSASEYPIKGRGGKGIKTANVT-E-NGPLAGMTTVTD-EDIMLVTDKGVIIRFDVANVSQTGRATLGVHLIKMD
E-HVATMTKVA-
>tr|A0A0E9ME10|A0A0E9ME10_9PROT DNA gyrase subunit A OS=Sulfuricella sp. T08 GN=gyrA PE=3 SV=1
MEDLITPQDMVVTLSHSGYIKSQPLEDYSAQKRGGRGQATA-MKEEDFIEKLFIANTHDYILCFSNRGQVYWIKVYEVPQGSRGSRGKPFVNMLQLD-GE
KINAILPVKEF--GHFIFMATASGIVKKTPLSDFSRPMKRGIIAINLDENDYLIGVDITDGQHDVMLFTDGGKAVRFDE-AVRATGRVSRGVMGVRLG--
KGVISLLVAENTQSVLTATENGYGKRTSIAEYTRHGRGTQGMIAIQTSE-RNGKVVAATLVNAEDEIMLITTGGVLIRTRVSEIREMGRATQGVTLINLD
KGKLIGLERVV-
>tr|A0A0B3ATA6|A0A0B3ATA6_9ARCH DNA gyrase subunit A OS=archaeon GW2011_AR17 GN=gyrA PE=3 SV=1
MEDLIPDEEVALMMTTSGYIKRMPIQEYRLQKRGGVGVKGTEK-EDDDVETIIHTSTHNYLLCFSNQGQVYWLKVYQVPEG-KYAKGKAIINLLNISEGE
RITTVIPIK-F--KHFLIMMTKTGLVKKTELMEYSRPRSNGIVGIKLIEGDELVTVKLTPG-LKFIIGTKKGMAVRFE---VRDVGRNSQGVRGIRLR--
-EVIGMEVAID-GQLLTITENGFGKRTDIPEYRLISRGGKGVINIQTTE-RNGDVVAIKTVK-NDEIMVVSKNGIVIRTPVTDIPN-SRNTQGVRIMRLK
-GKVSTVEKIK-
>tr|A0A061NQH5|A0A061NQH5_9BACL DNA gyrase subunit A OS=Geomicrobium sp. JCM 19038 GN=gyrA PE=3 SV=1
DEDLIPQENIVITVTHEGYIKRLPITTYKSQRRGGRGIQGMGT-DGDFVEHLFTTNSHQTILFFTNKGKVYRLKGYEIPELSRTAKGIPIINLLQIEK-E
EISTVIPID---DDNYLFFLTKKGIAKRTPLSAYAN-RKGGLFAINLRDDDELHGVR-TNG-DHVIIGTKNAMAIRFEE--VRSMGRTAGGVKAINLD--
NDVVGMDIVGTGQKVLIVSNNGYGKRTNEDEFRIQNRGGKGLRASTLT-ERTGHLVALRVISD-YDLMLITAKGVLIRIKADEISTLGRYAQGVTLIRVA
-DEVSSVAPFE-
>tr|C6HYH3|C6HYH3_9BACT DNA gyrase subunit A OS=Leptospirillum ferrodiazotrophum GN=gyrA PE=3 SV=1
PEALIPDEPYIVTLSYEGYIKRMPDAVLPTQRRGGKGRIGVTL-EDDCLIATLNARAHDTLLFFTDLGKVYRLKTYELPEAQRTARGKHLLSLL-SSPDE
RVAAILPVR---GDNLLLFGTVKGYFKKTRLSEYANIRQGGLIATVLEEGDRLARVL-LHPDRRLLVATRGGMSIRFEA--IRPTGRATRGVRAIRLS--
-D-----VVSFSDLLLVTTEKGFGKRVDTNLFRLQKRGGKGVRIA--TE--TGAVVAILKV--RDDIDVVTDTGRVIRIPSEEIRKVGRGAKGVKLVSLS
-SQETIVCAAI-
>tr|A0A0K0WQ96|A0A0K0WQ96_9BACT DNA gyrase subunit A OS=Leptospirillum sp. Group II 'CF-1' GN=gyrA PE=3 SV=1
IESMIPNDPCYITLTYQGYIKRVSHDAYPTQRRGGKGRSGVAL-EDDAVIITLTPTAHETILFFTDIGKVYRVKAHEIPEVQRTARGKPVRGFL-PAPEE
KVTRMLNVA---GDRSLVFVTVNGIIKRTALSAYSSIRQSGIIALTLREGDRLAQVL-ADADSHVLVATRRGMAILFPI--VTEQGRTASGVRAIRLR--
-DVADAEIVTE--PVAVVTEKGYGKRLDVAKFRHQHRGGMGLKIS--AK--IGAVVSLVKAGDTDDLTIITSKGVTNRVQANELRTMGRSAQGVIVMRLA
-DTIVSAVVSP-
>tr|I0IKD6|I0IKD6_LEPFC DNA gyrase subunit A OS=Leptospirillum ferrooxidans (strain C2-3) GN=gyrA PE=3 SV=1
FESLIPDDPCYINLTFQGYIKRLSKDAYPTQNRGGKGRIGVTL-DDDAVISTLSPTMHETILFFTDIGKVYRLKVHEIPEGQRATRGKSIRSLLALAPDE
KVTQLLS---FEE-KSLIFVTERGKIKRTQLIHYGQIRQSGIIAISLEEGDRLAQVM-GEPGTDILIATKGGKGILIPD--FRSMGRTASGVKGIKLA--
-DVVGAETIQD---VAVITARGYGKRVNTGDFRLQGRGGQGVRIL--AK--IGPVVSVIKVTGSEDVFLITQKGQALRIETSTIRLTGRTAQGVKLLNLQ
-EEIQCASLAP-
>tr|E0TJ67|E0TJ67_SULMC DNA topoisomerase (ATP-hydrolyzing) OS=Sulcia muelleri (strain CARI) GN=gyrA PE=4 SV=1
--NEVYNNKFVITITNTGYIKKNYLNKYKIG----------TY-KN-NLEKIIIAKNYQDILFFYENGKYFLLKVFKIPEL-KKSKGQAIQNLI-KNK-E
K--SSILIEK-LNKNYVILITKNGIIKKTTLIQYYK-P-NLI---KII--DYIIY---N---SEIFIAEKSGKII------IKKIALKND----------
---LYIICINDKEYILVVSEKGFV-KISN------SIGIKTINVT---TGF---L-AMKNVI-KNDIIIINKYGLTFRIPI--IGR-RR---KLI--NLK
D-KITYVAKVE-
>tr|K1LQE6|K1LQE6_9FLAO DNA gyrase subunit A OS=Bergeyella zoohelcum CCUG 30536 GN=gyrA PE=3 SV=1
IEDFIPNESVVVTISHAGYIKRTLLSEYRIQSRGGVGNKAATT-DEDFLEYIVSATNHQYMLFFTEKGKCYWLRVFEIPEGSRTAKGRAIQNLINIEPDD
KVKAYIRTNK--NQMFVVMITKNGTVKKTSLEAYSR-RTNGINAIEIREDDQLLGARLTNGSSQIMIATKKGKCIRFP---ARAVGRGSIGVRGISLE--
-DVVGMIVVND--SVLVVSEKGYGKRSAVL-YRETNRGGKGVITLNITE-KTGDLVAIQSVT-EDGLMIINKSGVAIRMSVDELRVMGRNTQGVKLINLK
-NEIAAIAKVE-
>tr|A0A0M4LLU6|A0A0M4LLU6_CORUL DNA gyrase subunit A OS=Corynebacterium ulcerans GN=gyrA PE=3 SV=1
EEDLIARENVVVTITSTGYAKRTKVDAYKSQRRGGKGVRGA-EKQDDVVRHFFVCSTHDWILFFTNFGRVYRLKAYELPEASRTARGQHVANLLEFQPEE
RIAQVIQLQ---AP-YLVLATAQGRVKKSRLSDYES-RSGGLIAINLAE-DKLIGAA--SNDDELLLVSEEGQSIRFSD--LRPMGRATAGVKGMRFR-D
-DLLAMTVVR-DACLLVATSGGYGKRTSLEEYSQQGRGGLGVVTFKYT-PKRGKLIAAVVVDD-DQIFAITSAGGVIRTEVNQIRP-SRATMGVRLVNLE
-GELLAIDRNV-
>tr|R5LTE9|R5LTE9_9CLOT DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium sp. CAG:149 GN=BN500_01270 PE=4 SV=1
AEDLIPDEDVVVAITNLGYIKRMSSDNFKSQNRGGKGIKGMQT-DEDYIEELLMTTTHHYMMFFTNTGRVYRLKAYEIPEAGRTARGTAIVNLIQLQP-E
KITATVPMK---EDKFLFMATKNGMVKRTPMKEYEN-RKNGLQAIVLREDDELIEVK-TDN-EDIFLVTKKGMCIRFHE--VRITGRVSMGVIGMKFD--
-DIIGMQMASQGECLLVVSEYGLGKRTPIEEFTSQLRGGKGVRCYRIT-E-TGYLVGAKLVDG-RQIMLITNEGIIIKMRVNTISIIGRNTSGVKLMDID
EGVVASIAKVR-
>tr|D7GRL3|D7GRL3_9FIRM DNA gyrase subunit A OS=butyrate-producing bacterium SS3/4 GN=gyrA PE=3 SV=1
VEDLISDDDTVIAMTNLGYIKRMSVDNFKSQNRGGKGIKGMQT-DEDFIEDLLMTTNHHYIMFFTNTGRCYRIKAYEIPEAGRTARGTAIVNLLQLQP-E
KVTAAIPMR---DDKYLFMATKGGMVKKTRMCEYSN-RKTGLQAILLREGDELIEVK-TDN-EDIFLATKFGMSIRFKE--ARITGRVSYGVIGMKLD--
-GVIGMQMASQGEYMLVASEKGYGKRTRISEFKLQLRGGKGLLCYNVT-E-TGNLVGMKLLDG-RDIMLITNEGILIRMGVDDISIIGRNTSGVKLMSID
DDRVASIAKVR-
>tr|R7AES3|R7AES3_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:43 GN=gyrA PE=3 SV=1
AEDLIPDDDIVVTMTNFGYIKRMSSDNFKSQNRGGKGIKGMQT-EEDYIEDLLMTTTHHYVMFFTNKGRVYRLKGYEIPEAGRTARGTAIVNLLPLMP-E
KITSIVPMK---DEKYLFMATRNGMVKKTPMKEYSN-RKNGLQAIVLRDDDELIEVK-TDN-EDIFLITKKGMCIRFHE--VRVTGRVSMGVIGMKFD--
-GVIGMQMASQGECLLVVSENGYGKRTPIDEFTAQNRGGKGVRCYKII-D-TGDLVGAKLVDE-RKIMLITNEGIIIKMAVSDISIIGRNTSGVKLMSID
EGVVASIAKVR-
>tr|E7GSB9|E7GSB9_CLOSY DNA gyrase subunit A OS=[Clostridium] symbiosum WAL-14163 GN=gyrA PE=3 SV=1
AEDLIPDDDVVVAMTNFGYIKRMSSDNFKSQNRGGKGIKGMQT-DEDYIEDLLMTTNHHYVMFFTNTGRVYRLKAYEIPEAGRTARGTAIVNLLQLMP-E
KITSIIAMK---DDKYLFMATRNGMVKKTSLKEYEN-RKNGLQAIVLRENDELIEVK-TDN-EDIFLVTKKGMCIRFHE--VRVTGRVSMGVIGMKFD--
-DVIGMQMSSQGECLLVASEYGYGKRTPIEEFNCQNRGGKGVRCYKII-D-TGDLIGAKLVDS-REIMLITNEGIIIKMSVNDISIIGRNTSGVKLMSID
DGAVASIAKVR-
>tr|F0RZW1|F0RZW1_SPHGB DNA gyrase subunit A OS=Sphaerochaeta globosa (strain ATCC BAA-1886 / DSM 22777 / Buddy) GN=gyrA PE=3 SV=1
LEDFIKDEQVVVLISNKGFAKRIRAEEYEAHGRAG-G--RTK--GD-FVNHMFVAFTHEYVMFVTNAGKAYYTKVFEIPES-KTAKGTSIKNIL-QET-E
K--SIISFK---EDHYLMMATRDGVVKKVSLNNFVN-K-RGIRALFLD--DELLS---ID---EVMLITKLGRGL------VRAMGRASRGVRGIRLLA-
-NVAGLLKVDSTKRILMITENGQGKQVNF-SFT-HGRGTQGQKIY---GGKASFV-GVLSVD-ENDVVCATLMGQTLRVHV-AISI-GR---GVKVVSMK
A-SIVAIASTE-
>tr|F4GM87|F4GM87_SPHCD DNA gyrase subunit A OS=Sphaerochaeta coccoides (strain ATCC BAA-1237 / DSM 17374 / SPN1) GN=gyrA PE=3 SV=1
VEDFIKNEEVVVVISNKGFIKRVVAEEYRSQGRGG-G--KAK--DD-FVEHLYVASTHDYVMFVSSFGKAYWIKVHEIPES-KVSKGSSIKQLI-DTG-E
E--SIINFT---DDQYLFMVTKHGVTKKVGLPAFRN-K-RGVRALFLD--DIMVQ---MD---DMMFVTAGGRGL------VRAMGRASRGVRGMKLLG-
-DVIGLLKVDD-RRILMITEKGQGKQVNF-NFN-HGRGTQGQLIY---KEKTSYV-NALAVN--NDVVVITMQGQTIRIHV-LIST-GR---GVRVVALK
P-SIVALAVTD-
>tr|G8QYU0|G8QYU0_SPHPG DNA gyrase subunit A OS=Sphaerochaeta pleomorpha (strain ATCC BAA-1885 / DSM 22778 / Grapes) GN=gyrA PE=3 SV=1
LEDFIKDEEVVVLISNKGFAKRIPSEEYEAHGRAG-G--RTK--GD-FVDHMFVASTHEYVMFVTNAGKAYYTKVFEIPES-KTAKGTSIKNIL-QDT-E
K--SIISFK---EDTYLMMATRHGVIKKVSLNNFRN-K-RGIIALNLD--DELLQ---VD---EVMLITKNGQGL------VRAMGRASHGVRGIRLLG-
-KVAGLLKVDFNKRILMVTENGQGKQVTF-SFS-HGRGTQGQKIY---GGKASCV-GALAVN-ENDVVCVTLMGQTLRIHV-HISI-GR---GVKVVTMK
A-CIVAIASTS-
>tr|K9T3X2|K9T3X2_9CYAN DNA gyrase subunit A OS=Pleurocapsa sp. PCC 7327 GN=gyrA PE=3 SV=1
DTDLIANEQAVILLTEQGYIKRMPVNTFGAQNRATRGKAAAKI-EDDVVEHFLTCCDHDNILFFSDRGVVYTLNAYHIPAGSRSARGVPIVQMLAISQGE
KITSIVAVQ---ENDYLIMLTRKGYIKKTALSAFSNIRANGLIAISLEEGDQLRWVRLAREEDSIILGSKGGMAIHFKA--LRPLGRATRGVKAMKLK--
-ELISMDILPSGPWLLAITTCGYGKRVPVSQFRLQNRAGMGVRAIKF--A-QDRLVAIHVVN-EDEMMIVSNRGIIIRQAVDAISLQSRMATGVRVQRLD
-DAIAAVALVP-
>tr|Q7NC97|Q7NC97_GLOVI DNA gyrase subunit A OS=Gloeobacter violaceus (strain PCC 7421) GN=gyrA PE=3 SV=1
DADLIANQEMVVLVTEQGYIKRLPVDTFDRQRRATRGKSGARM-EDDAVEHFITCCNHDTVLFFTNRGVVYALRGYQIPAGSRTAKGTPVVQLLPIPIEE
KVTSIVPVQ---SDEFLVMLTRTGFIKKTALAAFANLRANGLIAIGLEEGDELRWVRRARAEDDILVGSRAGMAIRFRA--LRPLGRTARGVKSMELR--
-ELVSMDILSCGPWVLVVTADGFGKRVPFSEFRAQNRGGMGVIATKF--Q-GDELAALRVVS-EDELMIVTARGVIIRQQSEEISQQSRAATGVRVQRLD
-DTIVGVAVVP-
>tr|L8LQ30|L8LQ30_9CHRO DNA gyrase subunit A OS=Gloeocapsa sp. PCC 73106 GN=gyrA PE=3 SV=1
DTDLIANEKAIILLTEQGYIKRMPVSNFEAQNRATKGKAGAKI-EDDVVEHFLTCCDHNHLLFFSNQGVVYSLNAYHIPIASRIARGTPIIQMLPIDTGE
KITSMVAVT---DDQYLIMLTRQGLIKKTALSAFSHIRSSGLIAISLVEGDQLRWVRLARSEDSVMIGSRHGMAIHFKA--LRPLGRSTRGVKAMKLR--
-ELISMDILPSGPWLLAITTGGYGKRVPVTAFRIQKRAGIGVKLIRF--E-KDKLAAIHVVN-EDELMMVTSRGIIIRQAVKAISLQSRSATGVRVQKLD
-EAIAAVALVP-
>tr|K9XQN5|K9XQN5_STAC7 DNA gyrase subunit A OS=Stanieria cyanosphaera (strain ATCC 29371 / PCC 7437) GN=gyrA PE=3 SV=1
DTDLIANEQAIIILTEQGYIKRMPVSTFEAQNRATRGKAAAKI-EDDVIEHFLTCCDHDTVLFFSDRGVVYSISAYQIPAASRTARGVPIVQMLPISQEE
KITSIVSVS---DNEYLIMLTQKGNIKKTALSAFSNIRANGLIAISLEEGDELRWVRLARTEDSVIIGTRKGMAIHFKA--LRPLGRATKGVKSMKLK--
-ELISMDILPSGPWLLAITNNGYGKRVPVTKFRLQNRAGMGVRAIKF--A-NDKLAAIHVVN-EDELMIITNRGIIIRQAVDAISLQSRNATGVRVQKLD
-DAIAAVALVP-
>tr|B7KBQ0|B7KBQ0_CYAP7 DNA gyrase subunit A OS=Cyanothece sp. (strain PCC 7424) GN=gyrA PE=3 SV=1
DLDLIANEQAVILLTEQGYIKRMPVSTFGQQSRATRGKSAAKI-EDDGVEHFLSCCDHDYILFFSDRGVVYVLGAYQIPSSSRTARGVPIVQMLPIPKNE
KITSMLAVS---EDCYLIMLTRQGYIKKTVLSAYSNIRANGLIAITLSEGDQLRWVRLAREEDSIIIGTRKGMAIHFKA--LRPTGRTARGVKSMKLK--
-EIISVDILPSGPWVLAITTGGYGKRVPVSQFRLQKRAGMGVKAIRF--D-HDQLVAIHVVN-DDEMMMVTNRGIIIRQAVDAITPQSRMATGVRVQRLD
-DAIAAVALVP-
>tr|Q8DJ59|Q8DJ59_THEEB DNA gyrase subunit A OS=Thermosynechococcus elongatus (strain BP-1) GN=gyrA PE=3 SV=1
DIDLIANDKSVILVTQQGYIKRMPVDTFEAQSRDGRGRKGAEI-EDDAVEHFFSCNDHDRILFFSDRGLVYALAAYQIPSGSRQARGTPIVQLLPIPREE
KITSVIAVQ---EDEYLVMLTRKGFIKKTPLAAFSHIRSNGLIAISLEEGDQLRWVRRTREQDTIIIGSRQGMAIHFRA--LRPLGRATRGVKSMNLR--
-ELVGMDILPAGPWVLVITTNGYGKRVPVQQFRLQNRAGMGITATKFKSN-EDQLAALRIVN-GDELMIVTSRGIIIRQKVMDISSQSRSATGVRLQRLD
-DAIVTAAVLP-
>tr|L8LYI5|L8LYI5_9CYAN DNA gyrase subunit A OS=Xenococcus sp. PCC 7305 GN=gyrA PE=3 SV=1
DIDLIANEQAVILLTEHGYVKRMPVSTFDAQNRATRGKAGAKI-EDDAIEHFITCCDHNTLLFFSDRGVVYSLPAYQIPTASRTSRGTPLLQMLPISQEE
KITSVVSVV---EEEYLVMLTRKGNIKKTALSAFKSIRSNGLIAISLEEGDQLRWVRLAKPEDSIIIGTHNGMAIHFKV--LRPLGRATKGVKSMKLK--
-ELISMDILPSAPWLLAITTNGYGKRVSVSKFRLQNRAGMGVRAIKF--Q-SDRLAAIHVVN-ADEFMIVTNRGIIIRQVVDAISLQSRSATGVRVQRLD
-DAIAAVALVP-
>tr|V9HH56|V9HH56_9CLOT DNA gyrase subunit A OS=Clostridium sp. 7_2_43FAA GN=gyrA PE=3 SV=1
IEDLIQEEEVVITLTHSGYIKRISADTYSSQRRGGRGIQAMST-EDDFVEHVNVVSTHSDVLFFTNRGRVYKLRAYEIPDG-RTAKGTNIINLIAIEQ-E
KIETVLSVK---NEGFLFMGTKQGLVKKTPLSEFKN-RKNGLIAINLRDGDELLKVK-TRG-ADIVIVTQDGNAIRFNE--VRPMGRTASGVRSINLR--
-DAVCMDIAVE-EDLLVISENGFGKRTPITEYKRQKRGGTGLITYKLS-E-TGKVIGATICKD-DELMLINTSGVAIRINVSDISVTSRSTMGVTLMRTT
EE-IAAITKIS-
>tr|A0A0M3EGT4|A0A0M3EGT4_TANFO DNA gyrase subunit A OS=Tannerella forsythia GN=gyrA PE=3 SV=1
PEDFYADDEMIITISHMGYIKRTPLSEFRAQARGGVGAKGSET-EEDFVEYIYPASMHATILFFTAKGRCFWKKVFEIPEGAKNAKGRAIQNFLNIDSDD
SVNAFIRIKT--NSHYLLFCTKKGVIKKTLLAAYSR-RQNGVNAITLHEGDGVIQVRLTNGNNDVLIANRNGRAIRFH---VRVMGRTAAGVRGMTLDE-
-DAIGMVCIKDKETILVVSEQGYGKRSKIDDYRITNRGGKGVKTIHVTE-KTGKLVGIKNVT-ENDLMIINKSGITIRMKVADLNIIGRATQGVRLINLE
RNEIASVCKVV-
>tr|A0A024FAX8|A0A024FAX8_UREPR DNA topoisomerase (ATP-hydrolyzing) OS=Ureaplasma parvum serovar 3 GN=UP3_c0279 PE=4 SV=1
---MIEKQNLNLVISRDGYIKTVSKKSFESSKYDELG-------ND-ILFYHNIINSHDKILIITSKAKLINLVAHKITS----MVGEHLNNYVK--N-E
K--AVYIWN--IDEYQLVLASRLNLIKRIELSE-LK---KQISIMKL--NDNLIS---K---QFIIAISKLGLAL------I---NRLAKGIKIMKLK--
-NVSAILITP-NGYNVQLFLERGSKCFNIS-----KRATTPTNLY--TK---VQV-LAAF---E-NVFYLLDQQ--QKINP---YL-NPTKLDTKISIYE
--QMIDDCFLS-
>tr|B5ZBX0|B5ZBX0_UREU1 DNA topoisomerase (ATP-hydrolyzing) OS=Ureaplasma urealyticum serovar 10 (strain ATCC 33699 / Western) GN=parC PE=4 SV=1
---MIEKQSLNLVISRDGYIKTVSKKSFESSKYDELG-------ND-LLFYHNVINSHDRILIITSKAKLINLIAHKISC----MVGEHLNNYAK--N-E
K--AVYVCN--VDEHQLVLGSKLNLIKRIELNE-LK---KQISIMKL--NDGLIS---K---QFVVAISKLGLVL------I---NRLAKGIKIMKLK--
-NISSILIVP-NGYSIQLFLDQGNKCFSIS-----KRAMTPSPLY--TK---AQV-LAAF---E-NVFYLLDEQ--QKINP---YL-NLIKLDSKINKYE
--LIIDDSFLS-
>tr|L7VUW4|L7VUW4_9BACT DNA gyrase subunit A OS=uncultured bacterium A1Q1_fos_140 GN=gyrA PE=3 SV=1
MEDLIPDEDLVVSITRGGYAKRTLASQYRTQKRGGKGVRGA-SRGDDVVEHFIATSNHHWLLFFTNAGRVYRTKAYNLPEASRDAKGGHVAGLLSFQPDE
QIAQVLAIR---AP-YLVLATRSGLVKKTRLAEYNS-RQAGVIAINFRD-DELIGAE--DSDDDILLVSRKGQAIRFAS--LRPMGRATSGVTGMKFR-D
-DMLSMSVIRAEQFVFTITDGGFAKRSRISEYRTQSRGGLGVKAMALG-NDRGGLVGAFIVVG-DEILSITSGGQVVRSPIADFRV-GRSTMGVKFVTPK
-KSVAVVARSV-
>tr|A0A0F2NSQ9|A0A0F2NSQ9_9GAMM DNA gyrase subunit A OS=Gammaproteobacteria bacterium BRH_c0 GN=gyrA PE=3 SV=1
VEDLIPVEDRVVTISHGGYAKTQPLDMYQAQRRGGTGTATA-VKDEDFVEHLLIASTHDTILCFTNAGKVFWLKVYQIPVAGRNSRGRPMVNLLP-LEGE
RVTSILPVREYTEDHFIFMATANGTVKKTSLQSFSRPRSVGLRAVELDDGDHLVGTAITDGTCDVMLFTSGGKVARFREGDVRAMGRTARGVRGIRLAEQ
E-VISLIIPD-DQQILTVSENGYGKRTQADDFPAKGRGGQGVIAMQASD-RNGALVGALLVAEQDEIMLISDQGTLVRTRVGEVPSLGRNTQGVRLIRVR
QDKLVSVARIE-
>tr|C5BSJ1|C5BSJ1_TERTT DNA gyrase subunit A OS=Teredinibacter turnerae (strain ATCC 39867 / T7901) GN=gyrA PE=3 SV=1
VEDLINEEDRVVTISHGGYAKTQPLDAYQAQRRGGMGAATS-VKDEDFVEHLLIANTHDYILCFTNAGKVFWLKVYQIPVAGRQSRGRPMVNLLP-LEGE
RITSILPVREFDEDRFIVMATSQGTVKKTPLSQFARPRSVGLRAIDLVEGDHLVGTAITDGQQDIMLLSSSGKAARFAEEQVRSMGRTSRGVRGIRMADH
R-VIAMVIPA-GGKVLTVSENGYGKRTDVDDFPTKGRGSQGVIAMQVSE-RNGGLVGAVQIFDGDELMMISDQGTLVRTRGDEVSLLSRNTQGVRLIKVR
ESHIVGVARIA-
>tr|A0A0G1WNT4|A0A0G1WNT4_9BACT DNA gyrase subunit A OS=Microgenomates bacterium GW2011_GWA2_47_8 GN=gyrA PE=3 SV=1
DEQLIPNEKAIITMSQSGYIKRVPRSTFKMQERGG-G--IMS--ED-TIDQLVTASTHDNMLFITDRGRVYQVRVWDIPES-RQSKGQAVVNLI-NEG-E
R--SVLAYS--HGVKYILMATKNGTVKKSKLTEYEN-R-SGIVAIKLE--DELAW---TD---DILLVTHEGKSI------VRPTARDTMGVRGVLLGK-
-EVVSVDIINQGADFLTIMEKGIGKKTAI-DFP-QRRGGQGVKVA---KDKTGKV-VSQIVP-CESVILTSTKGQVVKLPI-SVPR-GR---GVILMRFT
K-TIAAATCLT-
>tr|A0A0G1EQK5|A0A0G1EQK5_9BACT DNA gyrase subunit A OS=Microgenomates (Gottesmanbacteria) bacterium GW2011_GWA1_43_11 GN=gyrA PE=3 SV=1
DEDLIPNEQTIITLTKTGYIKRVPISTFKTQSRGG-G--IMT--ED-QVDMMSFSMTHDNVLFFSDRGKVYQTKAWDIPES-RQSKGQAVVNLI-NEN-E
R--SILTHG--DKAHYIFMATKKGVVKKTKIGEYEN-R-NGLVAINLE--DELSW---TD---EILLVTHNGKTI------VRPTGRNTMGVRGILIKN-
-SVVSMDIIDS-AFFLTVMEKGLGKKTPL-GFP-QKRGGQGVKVA---TPRTGAV-VSQLVP-SESLILTSMKGQVVKLPL-GVPT-SR---GVILMRFA
R-IVAAATFM--
>tr|A0A0G1CMH8|A0A0G1CMH8_9BACT DNA gyrase subunit A OS=Microgenomates (Gottesmanbacteria) bacterium GW2011_GWB1_43_11 GN=gyrA PE=3 SV=1
EEDLIANEETIITVTSGGYIKRLPRQTFKTQSRGG-G--IMT--ED-AVDKITTAMTHDNVLFFTDRGKVYQIKAWDIPES-RQSKGQAVVNLI-NEN-E
R--SLLTYH--EKAKYIFMATVRGTVKKTKLEEYEK-R-NGLVAIKLE--DTLSW---SD---EILLVTHSGKSI------VRPTGRDTMGVRGILLKD-
-SIVSMDIITETAEFLTIMEKGLGKKTPV-GFP-QKRGGQGVKVA---TTRTGQI-VAHFIP-AEFLILTSVTGQVVKLPI-SIPR-SR---GVILMRFA
K-AIAAATYI--
>tr|A0A0G1GSC4|A0A0G1GSC4_9BACT DNA gyrase subunit A OS=Microgenomates (Gottesmanbacteria) bacterium GW2011_GWB1_44_11c GN=gyrA PE=3 SV=1
DEQLIQNEDVIITMSESGYIKRVPRTTFKMQERGG-G--IMT--ED-IIDRLVSAQTHDNLLFFTDKGKVYQVRVWDLPET-RQSKGQAVVNLI-NET-E
R--SMLSYT--KGIDYIIMATKKGVVKKTRVSEYEN-R-NGLLAIKLE--DELAW---TD---ELLLVTHLGKSI------VRSTARDTMGVRGVLLTG-
-LLVSMDVITSKTDFLTIMEKGIGKKTAI-DFP-QRRGGQGIKVA---KDKTGKV-VSQIVP-TEAVIITSTKGQVVKLPI-SIPR-GR---GVILMRFT
K-TIAAATCLT-
>tr|A0A0G0UEX4|A0A0G0UEX4_9BACT DNA gyrase subunit A OS=Microgenomates (Curtissbacteria) bacterium GW2011_GWA1_41_11 GN=gyrA PE=3 SV=1
EEQLIANEDVIITMSQTGYIKRLPRTTFKMQERGG-G--IMA--ED-TIDQMVAAQTHDNMLFITDRGRVYQVRVWDIPES-RQSKGQAVVNLI-NEG-E
R--SLLAYS--QGVEYIVMATKKGTVKKSKLTDYEN-R-NGLVAIKLD--DELAW---TD---DILLVSHDGKSI------VRPTARDTMGVRGILLKP-
-SVVSMEVINTKADFLTLMEKGKGKKTAI-GFP-QRRGGQGLKVA---NAKTGNV-VSQLVP-CDSVILTSIKGQVVKLPI-SVPR-GR---GVILMRFT
K-TIAAATCLT-
>tr|A0A0G1UQJ3|A0A0G1UQJ3_9BACT DNA gyrase subunit A OS=Microgenomates (Gottesmanbacteria) bacterium GW2011_GWA1_48_13 GN=gyrA PE=3 SV=1
EEQLIANEDVIITMSESGYIKRLPRTTFKMQARGG-G--IMT--ED-TIDRLVSAQTHDNMLFFTDAGRVYQVRVWDIPET-RQAKGQAVVNLI-NEG-E
K--SVLTYS--SGVKFILMATKNGTIKKSKLTDYEN-R-SGLVAIKLE--DELIW---TD---DILLVSHDGKSI------VRPTGRDTMGVRGILFKG-
-AVVSVDVINE-ADFLTVMEKGIGKKTAI-DFP-QKRGGQGVKVA---KEKTGKV-VSQIVP-CESVIFTSTKGQVVKLPI-SVPR-GR---GVILMRFT
K-TVAAATCLT-
>tr|E8T2L0|E8T2L0_THEA1 DNA gyrase subunit A OS=Thermovibrio ammonificans (strain DSM 15698 / JCM 12110 / HB-1) GN=gyrA PE=3 SV=1
IESMIEDEEVIIFLTHKGFVARVSAGTYRTQSRSGTGVRGIKT-EGDFVKDMITASSKDYLLIFTNQGKVYWLKAYEIPKMERPSRGHSIRNFLPGAGNE
IVSRIIPVK---LNKDVFFVTQRGYVKRTPLKEFSNPRSTGINAINLEPGDRLVYVG-VSDKDNIILISKNGRAIKFPV--VRQMGRNARGVRGILLD--
-DVVAAAVVEPDRFLLIVTEKGYGKRVEIEEFHLQRRGGKGLIAA--SK--TGKVADATTLKDDEPIILVSKKGKIIRVKSADIPVYGRHTRGVRIQKLA
-DAVVSVSKVT-
>tr|G2H9T3|G2H9T3_9DELT DNA gyrase subunit A OS=Desulfovibrio sp. A2 GN=gyrA PE=3 SV=1
IEDLIPDEDVVITLSRRGYIKRTTLDNYQQQRRGGKGIAGVHT-EDDFVQDFLTTTNHQYLLLFTNHGRMHQIKVHRVPEGSRTAKGVHIANLV-QDKDE
LVTNVLTVR---EDRYFLFVTRRGMVKRSSASLYAKCRKTGLIAVGLRPEDELIMVR-VDENCHIVLTTGDGMAIRFQC--VRPMGRSATGVKGIALR--
-DVVACVILAETSMIMSVSANGFGKRTNADLYRVQSRGGVGVKNF--TK--TGDVIGAMPVRDDDALVLLTSTNKILRMGLDDVRSVGRATQGVRLVRLD
-GLVVGFDRID-
>tr|Q317S1|Q317S1_DESAG DNA gyrase subunit A OS=Desulfovibrio alaskensis (strain G20) GN=gyrA PE=3 SV=1
IEDLIPDEDVVITLSRRGYIKRTPLDSYQQQRRGGKGIAGVHT-DGDFVQDFLVTTNHQYLLLFTNKGRMFQLKVHQVPEGSRTAKGMHINNLL-PEENE
WVNTALTIR---EEKYFLFSTRKGMVKRSSASLYAKARRTGLIAVGLREGDELIMVR-VDDNCEVVLTTEKGIAIRFGC--VRPMGRSATGVKGIALS--
-DVVACVTVQGESEIMTVSRYGYGKRTLIDRYRVQSRGGKGVINF--TK--TGEVLGAMTVVSNDQLILLTSTNKIIRIGVKEVRSVGRATQGVRLVWLD
-GHVVGFDRVS-
>tr|G1V2L0|G1V2L0_9DELT DNA gyrase subunit A OS=Bilophila sp. 4_1_30 GN=gyrA PE=3 SV=1
IEDLLPDDDVVITLSRRGYIKRTSLGIYQQQRRGGKGVAGVHT-EDDFVQEFITTTNHQFLLMFTNKGRMHQLKVHQVPEGSRTAKGVHIANLV-PEKDE
WVNTILTVR---EDKSFLFATRRGMVKRSSAALYARSRKGGLIAVGLREDDELIMVR-ITDDDFVVLATADGIAIRFSC--VRNMGRGATGVKGIALR--
-DVVACLVLKESPAIMTISALGFGKRTNVDLYRVQSRGGKGIINF--TK--TGPVIGAKSVLDDEALVLLTSTNKIIRMGVDEIRSVGRATIGVRLVKLD
-GRVVGFDTVN-
>sp|Q1MQ89|GYRA_LAWIP DNA gyrase subunit A OS=Lawsonia intracellularis (strain PHE/MN1-00) GN=gyrA PE=3 SV=1
IEDLIPDDDVVITLSRRGYIKRTNLAIYQQQRRGGKGVAGLHT-EDDFVQEFITTTNHQFLLLFTNKGRMHQLKVHQVPEGSRTAKGTHIANIV-PEKEE
WVTTILTVR---DNKFFLFATRKGMVKRSSASYYARSRRTGLLAVGLREDDELIMVK-VTNNDFIVLATAEGFAIRFSC--VRNMGRGAAGVKGIALR--
-DVVACLILQETPAIMTVSNLGYGKRTSIDLYRVQTRGGKGIINF--TK--TGLVIGAKPVSDDNALVLLTSTNKIIRMSVDEVRSAGRATMGVRLVKLD
-GYVVGFDTVD-
>tr|A0A0E0SY62|A0A0E0SY62_DESVR DNA gyrase subunit A OS=Desulfovibrio vulgaris (strain RCH1) GN=gyrA PE=3 SV=1
IEDLIPDDDVVITLSRRGYIKRTTLDNYQQQRRGGKGIAGLHT-DDDFVQEFLTTTNHQYLLLFTNHGKMHQLKVHQVAEGSRTAKGVHIANLL-PEKDE
WVTTVLSVR---EDRFFLFVTKRGMVKRSSASLYARARKGGLIAVGLRDDDELIMVR-IHNDDHVVLTTGGGMAIRFAC--VRPMGRSATGVKGVALS--
-DVVACAVLPGSTEIMSISSNGYGKRTRIELYRLQSRGGKGVKNF--TK--TGDVIGAMPVRDDEALVLLTSTNKIIRMSVDEVRSVGRATMGVMLVRLD
-GIVVGFDRVD-
>tr|B6WUP4|B6WUP4_9DELT DNA gyrase subunit A OS=Desulfovibrio piger ATCC 29098 GN=gyrA PE=3 SV=1
IEDLIPDEEVVITLSRRGYMKRTSLENYQQQKRGGKGIAALHT-DDDYVQEFLTTTNHQYLCLFTNKGRMHQLKVHQVPEGSRTAKGVHINNLL-PEEGE
WVTTVLAVR---EDKYFLFVTKRGMVKRSSASLYARCRKSGLMAVGLREDDELVVVR-IREDSHIVLATADGYSIRFAC--VRPMGRVATGVKGIALR--
-DVVAGVILKETTEIMSISANGFGKRTRVDLYRLQSRGGKGIINF--TK--TGPVVGAMPVRDNDGLIMLTSANKVVRIGVEDVRSKGRATMGVMLVRLD
-GHVVGFDRVD-
>tr|A0A0D5N823|A0A0D5N823_GEOSN DNA gyrase subunit A OS=Geobacter sulfurreducens GN=gyrA PE=3 SV=1
LEDTIVEEDVVVTVSHTGYIKRTAVSQYRSQRRGGKGKTGMKT-EEDFVEHLFVASSKDFMLFFTDAGKVYQIKVYEIPEGGRATRGKAIVNLLNLQE-E
QITAILSVK----DRNIIMATRLGVVKKSPLREYAN-RSGGIIAVNLDDGDKLIAVA-TDG-QDVLLASKNGKSIRFHE--ARPMGRVSRGVRGMSLE--
DVVIGMEIINPGSTIFTVTENGFGKRTELDEYRVQSRGGKGIITIKTT-E-NGCVVDIMQVTE-NDLMLITDQGKILRIPVAQFSVIGRNTQGVRLMTAE
-NRIVAVAKLA-
>tr|A0A0B5I440|A0A0B5I440_9ARCH DNA gyrase subunit A OS=archaeon GW2011_AR20 GN=gyrA PE=3 SV=1
TEDLIQESNVVVTMTYSGYVKQTPLVEYRQQKRGGKGIIATGT-EEDLVKDLFITSNLNTLLFFTNKGKCFQLKTYELPLEGRYSRGKAIVNLLKLEQDE
KVNTILPIS---EGYLIF-MTRKGIIKKTKLNEYENPRSSGLQAIRLIEKDELVNVI-SSGNDEVMIASKFGLASRFNE--ITSVGRNSVGVRGIRLN--
-DVIGMEKVNETSSLLTVTNNGYGKRTLISEYRLIRRGGKGVTNI--KR--NEGVVAIKPVYEDDEIMIMTEKGIVIRLPVKGISVIGRNTQGVKVIKLD
-NKVSSVAKIS-
>tr|A0A0F9Q7V4|A0A0F9Q7V4_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_0736960 PE=3 SV=1
PEDLIKEEDVAITYTSSGYIKRTSLDNYHFQIRGGKGKRGISM-PEDVVQDLFISSTHSYLLFFTNKGRLYWLKALEIPDVGVSGRGKSINNLLQLSPEE
KVRSIVAVK---GDRYVVMITSKGRMKKTKLSGFRNIRRGGIIAIGLSRKNELLSAK-TDGQRDILIGTKLGKATKFKE--IRPMGRQAAGVKAITLR--
-DIIGMIVVG-DEYVFTASEKGRGKKTKVDLYPLHRRGGKGVINL--NR--IGKALGMVGIS-EEELLLITKIGKVIRIKTGQVRPSGRSTQGVKIINLQ
-GKVVSMAKVR-
>tr|W5X225|W5X225_BDEBC DNA gyrase subunit A OS=Bdellovibrio bacteriovorus W GN=gyrA PE=3 SV=1
DEDLIADEPMVVTVTNTGLIKRIPVEEYRVQKRGGKGLKGMET-EEDYVTDIFTASTKTMLLVFTDKGKVYWCKVHKLPLGTRTSKGRSLANVV-QASGE
KVRSILP-----DNKFVVMLTEKGIIKKTSLDAFANPRTAGIIALTTDLEDGVIAVK-SDGKSDVFIATREGMSIRFNE--VRGMGRTARGVKAITLA--
-DVVAMEVLEKTDTILMVTSKGYGKRSPVDEYRIQSRGGVGIITQ--TK--VGVVVGTKKVADMMELILSTDKGQVIRMKVTDISVLGRNTQGVRLINID
-KETVTGVAVI-
>tr|D3PF27|D3PF27_DEFDS DNA topoisomerase (ATP-hydrolyzing) OS=Deferribacter desulfuricans (strain DSM 14783 / JCM 11476 / NBRC 101012 / SSM1) GN=DEFDS
-KNLIPDNPVIIIYTDDGFIKKENISKVTKTGKTTN--------ND-SAKFIINTTNHKKLLLFTDTGKLYYLNVYDIPEGSGNSKGTHISNLI-KNN-D
K--LIRT-----SNYDMVCITEKGLVKRTSLEEYKN-K-NGSLVLKLN-D-KLLK---N--ENYLLMLSKQSKYI------VRTVARLAKGVVGM--LN-
-NKIVDPMLE-EYLLCTITNKGFIKLTPL-EYS-QNRKTKGSYVM--TK--TGEI-VQI-LA-TNNCILITNTGQLIKIDI-NISV-NR---GQPIEYKL
H-YIV-SATFL-
>tr|Q2LYA0|Q2LYA0_SYNAS DNA gyrase subunit A OS=Syntrophus aciditrophicus (strain SB) GN=gyrA PE=3 SV=1
IEDMIAEEEMVVTYSQGGYIKRNPSSLYRTQRRGGRGKVGMMT-EEDVVERLFIASTHDYVLIFTNAGRLYWLKVYQIPQAGRMAKGKPIVNLINIGP-E
RVAAVLPVRG----QAVIMATRAGIVKKTDLTAYSN-RSGGIIALSIDEGDELVDVK-TGG-QDVFLATRKGKAIRFKE--IRTMGRTARGVRGISMD--
DAVIGMDIPR-GNAIVTVSEKGCGKRTAVSEYRLQKRGGKGMINLRIV-P-GGLVADILQVTE-EDLLLMSNSGKIIRMKVEDVPLIHRVTQGVKLIELD
-EQLVGMTSAE-
>tr|Q3A8M4|Q3A8M4_PELCD DNA gyrase subunit A OS=Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1) GN=gyrA PE=3 SV=1
LEDLIVDEDMVVTVSHSGYIKRNAVSLYRSQRRGGKGVTGMRP-EEDFVEQLFIASTHSFVLVFTDAGKVYWLKVHEIPQGGRASRGKAIVNLLQLQS-E
NVTSILPVR----GRYIIFATQNGIVKKTDLMAYAN-RSGGIIALTIDEGDRLVSTR-SDG-MDVLLASQNGKAIRFPE--ARAMGRTSRGVRGMALE--
DQVIGMEVVSDAATLVTVTEHGYGKRTNLDEYRQQGRGGKGIITIKTS-E-NGKVVDIKLIND-FDLMFITDGGKVLRTRVADLSVIGRNTQGVRLMVLE
-GRIVAVAKLA-
>tr|C6E7Q9|C6E7Q9_GEOSM DNA gyrase subunit A OS=Geobacter sp. (strain M21) GN=gyrA PE=3 SV=1
LEDTIVEEDMVVTISHTGYIKRNAVTLYRAQRRGGKGKTGMKT-EEDFVEQLFIASTKDYLMFFTDAGKVYWLKVYEIPEAGRAARGKAIVNLLNLAA-E
KITTILPVK----DKFIMMATRNGVVKKTNMMEYSH-RVGGIIAVNLDEGDKLITVA-TDG-QDVLLASANGKAIRFKE--VRTVGRVSRGVRGMTLE--
DVVIGMEILNEDSTIFTVTENGYGKRTEISEYRSQSRGGKGVITIKTT-E-NGNVVDIKQVND-NDLMLITDQGKILRVPVAGFSIIGRNTQGVRLMVKE
-NRVVAVARLA-
>tr|A0A0D2JFV3|A0A0D2JFV3_9DELT DNA gyrase subunit A OS=Desulfarculus sp. SPR GN=gyrA PE=3 SV=1
MEDMIAEEEMVVTMTHSGYIKRSPISLYRSQLRGGRGKRGMDT-EEDFVSSLFVASTHSYLLVFTAMGRLYWLKVHELPQGGRATKGKAIVNLLNLLP-D
TVSTVLVVK----DKEVFMATQKGTVKKTNLDAFSR-RSGGIIAINLAEDDYLVAVR-TDK-MEIFLATQNGQAIRFSE--VRSMGRTAAGVKGIDLS--
DAVVAMEAIAGTPTILTVTQNGYGKRTMLEEYPLRNRGGKGVITIKTT-E-NGLVVGALVVEE-DEIMMVSEQGNIIRTKVGGISVIGRNTQGVKLINLS
-GKLVAVARLA-
>tr|A1AJX6|A1AJX6_PELPD DNA gyrase subunit A OS=Pelobacter propionicus (strain DSM 2379) GN=gyrA PE=3 SV=1
LEDTIMDEEMVVTISHTGYIKRSAVDLYRSQRRGGKGKTGMKT-EEDFVEQLFIASTKDYLLCFTDAGRMYWLKVYEIPEGNRTTKGKAVVNLVNVGM-E
KITTILPVK----HTFLFMATRNGVVKKTPLIEYSN-RSGGIIAVNLDDGDKLIGVA-TDG-KDVFLASRNGKAIRFSE--VRSMGRVTRGVRGMNLN--
DHVIGMEIVHNGSTIFTVCENGYGKRTDLDEYRDQSRGGKGIITIKTN-A-NGSVVNVMQVSD-NDLMVITDNGKILRVPVSGFSVIGRNTQGVRLITTE
-KKVVAVARLA-
>tr|B3E999|B3E999_GEOLS DNA gyrase subunit A OS=Geobacter lovleyi (strain ATCC BAA-1151 / DSM 17278 / SZ) GN=gyrA PE=3 SV=1
LEDTIEDAEMVVTVSHTGYIKRSAVDLYRAQRRGGKGKTGMKT-EEDFVEQLFIASTKDFLLFFSDMGRVYRIKVYEIPEGSRTTKGKAVVNLVNVQE-E
KITAILPVK---EDLYLLMATRNGVVKKTPLVEYLN-RTTGINAVNLDEGDKLISVA-TDG-KDVFLASRHGKAIRFPE--ARPMGRVTRGVRGMNLE--
DEVIGMEVVDPGSTIFTLTENGFGKRTDLDEYRGQSRGGKGLITIKTT-T-NGLVVGVMQVNE-NQLMVITDQGKILRVPVAGFSVIGRNTQGVRVMVTE
-QKIVAVAKLA-
>tr|Q0F2K2|Q0F2K2_9PROT DNA gyrase subunit A OS=Mariprofundus ferrooxydans PV-1 GN=gyrA PE=3 SV=1
VEDLITEEDMVVTISNEGYIKRNATSLYRAQRRGGQGKTAMTT-DEDFVAQLMVASTHDYLLFFSDQGRVFRKKVYEVPQAGSTARGKALVNLLPVEK-E
RISATLAIRN----RFIIMATKNGVVKKTRLSEYQN-RANGIIAIKLDDDDGLISVL-SNG-EDVMLATSGGKAIRFAE--VRPMGRSTRGVTGMRLP--
CNVISMTLVS-EATLLAVSENGFGKRTSVSEYNVQKRGGQGVFTLKTG-G-NGDMVAALLVHD-DQVMMMTDSGRLVRIRLNGVSVIGRNTQGVKLIACK
-GRVIGAVRVA-
>tr|A0A0B6WWI0|A0A0B6WWI0_9BACT DNA gyrase subunit A OS=Pyrinomonas methylaliphatogenes GN=gyrA PE=3 SV=1
IEDLIADEDVVITVTNSGYIKRTPVTTYQRQGRGGKGRFGAAA-NGDFVEHLFVASTHAYLLIFTDDGQVYKLKVHEIPDAPPAARGKAIVNLINIPS-R
KLAGIVAVRD----HYVVMVTRNGVIKKTALSEFQN-RSNGINAINVDEGDALLDVV-TDG-KRIFIATHDGMAIRFDE--VRPMGRAARGVRGIELR--
DYVVALCAVSKHERMLSISEQGYGKQTPISDYRLQSRGGRGVINMRTT-E-TGKVVAVFPVED-SEVMIITQHGKLIRIEASEIRKTGRSASGVRLIKTE
-GKVTSASLLE-
>tr|A0A0A8WNZ4|A0A0A8WNZ4_9DELT DNA gyrase subunit A OS=Geobacter sp. OR-1 GN=gyrA PE=3 SV=1
LEDTIVEEDMVVTVSHTGYIKRNAVTLYRAQRRGGKGKTGMKT-DEDFVEHLFIASSKDYLMFFTDAGRCYWMKVYEIPEGGRATRGKAIVNLLNLNP-E
KISAILSVK----DRYIMMATRQGVVKKSPLREYSN-RSGGIIAVNLDEGDKLITVA-TDG-QDVLLASRNGKSIRFKE--ARPMGRVSRGVRGMTLE--
DMVIGMEILNDGSSLFTVTENGYGKRTELSEYRLQSRGGKGIITIKTT-E-NGCVVDIKQVTE-NDLMLITDQGKIIRMPVAGFSVIGRNTQGVRLMVTE
-ERIVAVAKLA-
>tr|R6VK65|R6VK65_9FIRM DNA gyrase subunit A OS=Firmicutes bacterium CAG:227 GN=gyrA PE=3 SV=1
MEDLIPKENTVIAMTKLGYIKRMTVDNFRSQNRGGKGIKGMAT-HNDYMEELLMTTTHHYLMFFTNMGRVYRLKAYEIPEASRTARGTAIVNLLSLQA-E
KITAVIPVN---AGEFLFMATRKGVVKKTPIEDYSN-RKTGLAAISLRDDDELIEVK-TDG-KDVILITKFGQCIRFHE--VRQTGRVSMGVRGINLQ--
-EVIGMQLSCQGDYLLIVSEKGMGKRTSVGEFTCQNRGGKGVKCYKIT-E-TGNVVGVKAVNE-NEIMLITTEGIIIRLECKDISILGRITSGVKLMNLK
D-TVASIAKVR-
>tr|R5BWM7|R5BWM7_9FIRM DNA gyrase subunit A OS=Blautia hydrogenotrophica CAG:147 GN=gyrA PE=3 SV=1
MEDLIPKQNTVITMTKLGYIKRMTVDNFRSQNRGGKGIKGMQT-ENDYIEELLMTTTHHYLMFFTNTGKVYRLKAYEIPEAGRTARGTAIINLLQLAP-E
KITAVIPLN---EGKYLMMVTKKGLVKRTPILDYEH-RKTGLAAIVLRDEDELIEVK-TDN-KHIILVTKEGMCIRFKE--VRSTGRVSMGVRGMNLS--
-SVVGMQLDTQGDCLLFVSEKGMGKRTSISEFTCQNRGGKGVKCYKIT-E-TGNVIGVKAVNE-NEVMMITTEGIIIRLQCSDISMLGRITSGVKLINLD
G-KVASVAKVR-
>tr|R7EBL4|R7EBL4_9FIRM DNA gyrase subunit A OS=Roseburia sp. CAG:471 GN=gyrA PE=3 SV=1
MEDMIPNENTVITMTKLGYIKRMTVDNFRSQNRGGKGIKGMQT-EDDYIDELLMTTTHHYLMFFTNMGKVYRLKAYEIPEAGRTARGTAIINLLQLQA-E
KITAVLSLK---QGQYLFMATKSGIVKKTPIQDYAN-RKTGLAAISLKDDDELIEVK-TDN-KDIILVTKYGQCIRFKD--VRSTGRVSMGVRGINLS--
-GIIGMQLCSQGDYLLIASEKGMGKRTSMSEFSVQNRGGKGVKCYKIT-E-TGNVVGVKAVND-NEVMMITTEGIIIRIACSDISILGRITSGVKLMNLD
K-SVASIAKVR-
>tr|D4J4X4|D4J4X4_9FIRM DNA gyrase subunit A OS=Coprococcus catus GD/7 GN=gyrA PE=3 SV=1
VEDLIKRENTVIAMTQLGYIKRMTMDNFRSQNRGGRGIKGMTK-DEDCITELMMANTHDYILFFTNKGRVFRLKGYEIPEASRIARGTALINLLQLEP-E
KVTATIPLE---NDKYLFMATKNGMVKKTSIMEYIN-RKTGLLAIGLREDDELIEVK-TDE-DLIYLVSQKGMSICFKQ--VRATGRTSMGVIGMDLD--
-DIVGMQVSSQGEAVLIVSEKGLGKRTMLEEFNVQNRGGKGLKCYKIT-D-TGLVVGVKCVNE-DELMIITTGGIIIRMPVEGISILKRITSGVKLIQLD
G-VVASIAKIR-
>tr|U2D2H6|U2D2H6_9FIRM DNA gyrase subunit A OS=Blautia sp. KLE 1732 GN=gyrA PE=3 SV=1
TEDLIPRENTVIAMTKLGYIKRMTVDNFRSQNRGGRGIKGMQT-EDDYIEELLMTTTHHYLMFFTNTGRVYRLKAYEIPEAGRTARGTAIINLLQLAP-E
KITAVIPLR---EGHYLMMATKKGLVKKTPIKDYEN-RKTGLTAIVLRDDDELIEVK-TDN-KDIILVTRDGQCIRFKE--VRSTGRASMGVRGMNLT--
-GVVAMQLNTQGDYLLVVSENGMGKRTAMSEFVVQNRGGKGVKCYKIT-E-TGNVVGAKAVNE-NEIMMITTEGIIIRLQCADISVLGRITSGVKMINLT
-GTVASIAKVR-
>tr|R7CVV7|R7CVV7_9BACE DNA topoisomerase (ATP-hydrolyzing) OS=Bacteroides sp. CAG:462 GN=BN666_01433 PE=4 SV=1
PEDFYADDEMVITISHLGYIKRTPLSEFRAQNRGGVGAKGSDT-DTDFVENIYPATMHNTMLFFTQKGRCYWLKVYEIPEGSKNSKGRAIQNLLNIDPDD
MVTAFIRVKN--NNHYLLFCTQKGTIKKTCLEQYSR-RQNGVNAINIVDDDRVIEVRMTNGDNEIIIANRNGRAIRFH---VRVMGRTATGVRGITLD-G
-DVIGMICIKDKESIMVVSEQGYGKRSDIE-YRITNRGGKGVKTLNITD-KTGKLVAIKSVT-ENDLMIINKSGITIRLKVADVRIMGRATQGVRLINLE
RNQIASVCKVN-
>tr|G5G978|G5G978_9BACT DNA gyrase subunit A OS=Alloprevotella rava F0323 GN=gyrA PE=3 SV=1
PEDFYANDEIVITISHLGYIKRTNLDEFRAQARGGVGSRGGTT-DSDFIEYIYPAMMHDTMLFFTACGRCYWLKAYELPEGTKNAKGRAIQNMLNIEKDD
AINACLYVKS--NSHYVVFCTKNGTIKKTSLSDYSR-RANGVIAINIREDDRVVSAVLTNGTDELVIANRNGRAIRFN---VRVMGRTATGVRGITLD--
-DVVGMVCVNDKETIMVVSEKGFGKKSAIE-YRKTNRGGKGVKTLQITE-KTGKVAAIKSVT-DDDLMIINKSGIVIRLKTSEVRVMSRATQGVKLIDLK
RNMISSVCKCP-
>tr|K2JN64|K2JN64_9GAMM DNA gyrase subunit A OS=Gallaecimonas xiamenensis 3-C-1 GN=gyrA PE=3 SV=1
IEDLIAEEDVVVTLSHEGYVKYQALADYEAQRRGGKGAAT-KMKDEDFIEQLLVANTHDTILCFSSRGRLYWLKVYQLPLASRTARGRPIINLLPLE-DE
RITAIL--P--EEGKYIFMATAFGTVKKTALTEYSR-RSNGIIAVNLNEGDELIGVTITDGSNEVMLFSDEGKVVRFSEDQVRAMGRGATGVRGINLE--
-GVVSMVIPSAEVDILTVTENGYGKRTAQDEYPAKSRATKGVVSI--SE-RNGKVVGAVAVE-SDEIMLISNRGTLVRTRVNEVSRVGRNTQGVTIIRTA
-DKVVGLQRIA-
>tr|K1YS63|K1YS63_9BACT DNA gyrase subunit A OS=uncultured bacterium (gcode 4) GN=gyrA PE=3 SV=1
HEDLIASEDVVVTLSHEGYAKIQAITDYQAQRRGGRGTATG-IKEEDFVERLFIANTHDTMLCFSNRGKVYWLKVYLLPQGSRTARGKPLVNLLPLE-GE
RINTILPIREYTANNYIFMATAFGTVKKVGLEHFSNPRSNGIIALDLSPGDNLIGAAITDGKQEVMLFSDAGKAVRFDEGQVRAMGRTAHGVRGMRIKD-
-QIISLIIVKPDEAILIATENGYGKRTAVTDFPNVNRGAQGVIAVQVSE-RNGKAVSAIQVCAGSEIMLISNQGTLVRIRVDEVSLIGRNTQGVKLINLS
VDTLVGVQQVE-
>tr|K2EQJ1|K2EQJ1_9BACT DNA gyrase subunit A OS=uncultured bacterium (gcode 4) GN=gyrA PE=3 SV=1
REDLITPEDVVVTLSHEGYAKIQAVTDYQAQKRGGKGTATK-VKEEDFVERLFIANTHDTILCFSNKGKVYWLKVYLLPQGNRTSRGKPLINLFPLE-DE
RINTILPIREYLPNHYIFMATAKGTVKKVPLEQFSNPRSNGIIAVDLQPDDNLINVALTDGKQEIMLFSDAGKAVRFAEDQVRSMGRTAMGVRGMRLKDQ
K-LISLVIAN--GAILTATENGYGKRTAISEFSVVNRGAQGVIAIQVGE-RNGKAVCAIQVDAGDEIMLISSQGTLVRTRVDEISVIGRNTQGVRLINLG
EGNLVGVQRVE-
>tr|A0A0M2HUM3|A0A0M2HUM3_9MICO DNA gyrase subunit A OS=Microbacterium hydrocarbonoxydans GN=gyrA_1 PE=3 SV=1
MEDLIAEEEMVVTVTRDGYIKRTRSDNYRSQHRGGKGVKGA-QRADDIVEHFFVTTTHHWLLFFTDKGRVYRSKTYEVPESGRDAKGTHVANLLALQPGE
KIAQILDIR---AD-YLVLATRDGLVKKTSLSSYDT-RQGGVIAIRLNDEDELVSAL--NAEDDILLISRRGMSVRFSE--LRPMGRATAGVKGMKFR-D
-GLLSASVAAPGQYVFVVTDGGYAKRTAIDEYRVQGRGGFGIKVAKLN-D-RGTLAGGLMVAD-DEVLVVLSSGKVVRSAVAEVPA-GRDTMGVVFARTT
-ARILAIARNG-
>tr|W7YBL2|W7YBL2_9BACL DNA gyrase subunit A OS=Paenibacillus pini JCM 16418 GN=gyrA PE=3 SV=1
DEDLIPREEVVITITHTGYIKRLPANTYRSQKRGGRGVVGMDT-DQDFVKHLFVSNSHHYLLFFTDKGKVYKLKAYEIPELGRTARGTAIINLIQIEQ-E
TVYAVIPVQ---SDKYLLFATRKGIVKKTPLEDYIN-RKGGLIAINLREDDSLIEVK-TEG-QEMIMGTAQGMSIRFSE--VRSMGRGATGVKGINLD--
-NVIGMDVVDQDLDVLIVTSKGYGKRTPASDYRSQTRGGKGIKTINVT-D-NGPVVALKIVKE-EDLMIITSSGTLIRTSMEGISTMGRYTQGVKLINIR
D-SVGTVCIAD-
>tr|A0A0B0HXS6|A0A0B0HXS6_9BACL DNA gyrase subunit A OS=Paenibacillus sp. P1XP2 GN=gyrA_2 PE=3 SV=1
DEDLIPREEVVITITHTGYVKRLPANTYRSQKRGGRGVVGMDT-DEDFVEHLFVTNSHHYLMFFTDRGKVYRLKAYEIPELSRTARGTAIINLIQIEQ-E
TINAVIPVE---NDKYLFFVTRSGIVKKTPLEDYVN-RKGGLIAINLREDDSLIEVK-TDG-QEVIMATAQGMSIRFSE--VRSMGRSATGVKGITLD--
-DVIGMDVVDKDLDTLIVTAKGYGKRTPLSDYRSQTRGGKGIKTLNVT-E-NGPVVGLKVVKD-EDLMIITSSGTLIRTSIDGISIMGRYTQGVKLINIR
D-TVATVCRVD-
>tr|I0YQD9|I0YQD9_9CHLO DNA gyrase, A subunit OS=Coccomyxa subellipsoidea C-169 GN=COCSUDRAFT_18563 PE=4 SV=1
VEDVIPNRASLLVFSRRGYIKRMPTDLFSVQGRGG-G--SA-R-DD-TVEEVAHVMDHDTVLFFSPDGICRALKAYQIPQS-RTAAGTPLTQARPLTG--
---SIMSLG--D-DDFLVMLTKNGLIKRTPMKLFAN-R-GSLTAIKLR--DELMW---V----SVLLASSDGTVI-------TPQSRVAQGLKSMVLA--
-GLVGMSVLPAVPSLLLVTENGLGKRVPL-MFR-QRRGGKGRRGI--N------D-LSA---VNEEMLLTTAGGMMNRTAV-TIRR-SRMARGVNVANLQ
G-SVQAITILR-
>tr|A0A0H3K5M6|A0A0H3K5M6_SYNP6 DNA topoisomerase (ATP-hydrolyzing) OS=Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1) GN=gyrA PE=4 SV=1
-----SDREQLQAASATELEPWLKAKSGA---------------TD-FPKVLQWADPRQDLLVITAEGRAYRRSLREVHPP-I-------ANLLPTGA-I
---ATLLLP--SEERSLLPLSSQGRVKRLALTELAE-S-RGLQLLKLA--EIIQA---A----EVLLGSSGGRLL------LPLASRISRGQPRLRLR--
-GPLGCLSLPS--DLLLVSTLGLVKRLPL-LLR-CRAGDLGNNAF--TKR---DL-ALLPAP----LAIFASDQRLWQRSI-TIAV-GT---GQTLFNLR
T-TLQSATTLE-
>tr|A0A0R2VUC8|A0A0R2VUC8_9FLAO DNA gyrase subunit A (Fragment) OS=Polaribacter sp. BACL8 MAG-120419-bin8 GN=ABR93_04035 PE=4 SV=1
IEDMIPDEQVVITISHAGYIKRTALSEYKTQNRGGVGQKASAT-NEDFLEHLFVGTNHQYMLFFTQSGKCFWMRVYEIPEGSRTSKGRAIQNLINISQED
KVKAFICTQK--NSHYVIMATKKGIVKKTTLEQYSR-RTNGINAIGVREGDELLEAKLTTGTSQVFLGLKSGKAIRFE---TRPMGRGASGVRGVSLADQ
-DVIGMITVHNEDHILVVSEKGYGKRSSME-YRVTNRGGKGVKTISITE-KTGGLVAIKNVT-SDDLMIINKSGIAIRLGVEDLRVMGRATQGVKLINIR
-NSIAAVAKVM-
>tr|G2PPI8|G2PPI8_MURRD DNA gyrase subunit A OS=Muricauda ruestringensis (strain DSM 13258 / LMG 19739 / B1) GN=gyrA PE=3 SV=1
IEDMIPDEQVVITISHAGYVKRTPLTEYKTQNRGGVGQKASST-NEDFLEHLFVGTNHQYMLFFTQKGKCFWMRVYEIPEGSRTSKGRAIQNLINIEQDD
KVKAFICTQK--NSHFVIMATKKGTVKKTSLEQYSR-RQNGINAITIREDDELLEAKLTTGTSQIFLGLKSGKAIRFE---TRPMGRNASGVRGIRLAD-
-DVVGMVSVHNEDDILVVSERGYGKRSNIE-YRITNRGGKGVKTISITK-KTGDLVAIKNVT-TDDLMIINKSGIAIRMGVEDLRVMGRATQGVRLINLK
-SSIAAVAKVM-
>tr|A0A0R2TP80|A0A0R2TP80_9FLAO DNA gyrase subunit A OS=Cryomorphaceae bacterium BACL7 MAG-121220-bin8 GN=ABR90_06620 PE=4 SV=1
MEDMIPDEQVVLTISNAGYIKRTPLVEYKTQNRGGVGQKGSTT-NEDFLEHLFVGTNHQYMLFFTQKGKCFWMRVFEIPEGSKTSKGRAMQNLINIEQDD
EVKAFICTQK--NSHYVIMTTKKGQVKKTSLEQYSR-RSNGINAITIKDGDELLEAKLSNGNSQVLIAVKSGKCIRFE---TRPMGRNASGVRGIRLKD-
-DVVGMISVNDSSDILVVSENGYGKRSSLE-YRITNRGGKGVKTISITE-KTGSLVSIKNVS-SDDLMIINKSGIAIRMEVSSLRVMGRATQGVKLINLK
-SSIAAVAKVV-
>tr|I0WG51|I0WG51_9FLAO DNA gyrase subunit A OS=Imtechella halotolerans K1 GN=gyrA PE=3 SV=1
IEDMIPDEQVVITISHAGYIKRTPLKEYKTQNRGGVGQKASNT-DQDFLEHLFVGTNHQYMLFFTQKGKCFWMKVYEIPEGSRTSKGRAIQNLINIETDD
KVKAFICTQK--NTHFVIMATKKGIVKKTTLEAYSR-RQNGINAITVREDDELLEALLTTGKSQVMLAVKSGKAIRFE---TRPMGRNASGVRGISLAE-
-DVVGMIAIENEETVLVVSENGYGKRTFIDVYRITNRGGKGVKTISITE-KTGNLVAIKSVT-SDDLMIINKSGIAIRLTVEDLRVMGRATQGVRLINIK
-DSIAAVAKVM-
>tr|A4CK42|A4CK42_ROBBH DNA gyrase subunit A OS=Robiginitalea biformata (strain ATCC BAA-864 / HTCC2501 / KCTC 12146) GN=gyrA PE=3 SV=1
IEDMIPDEQVVITISHAGYIKRTPLTEYKTQHRGGVGQKASAT-NEDFLEHLFVGTNHQYMLFFTQKGQCYWLRVFEIPEGSRTSKGRAIQNLINIEQDD
KVKAFICTQK--NSHFVIMATKKGVVKKTSLEQYSR-RQNGIIAIGIREGDELLEARLTTGSSQIFLGLKSGKAIRFE---TRPMGRSASGVRGITLAD-
-DVIGMVSVHDDEDILVVSENGYGKRSSLD-YRITNRGGKGVKTISISK-KTGGLVAIKNVS-SDDLMIINKSGIAIRMSVEDLRTMGRATQGVRLINLK
-NSIAAVAKVM-
>tr|A0A0R1L8J2|A0A0R1L8J2_9LACO DNA gyrase, A subunit OS=Lactobacillus koreensis JCM 16448 GN=FC99_GL001141 PE=4 SV=1
DEDLIAEEDVVVSLTHNGYIKRLPTSEFKAQNRGGKGVQGMGV-DDDFIEHLVATSTHDMLLFFTNTGKVYRMKGYEIPEYGRTAKGIPVINLLGI-NNE
HVQAVINVA--NANRDLFFTTVQGTVKRTPVDEFAN-RSNGLKAINLKEDDELIDVD-INA-ANMIIGTHLGYAVSFAA--VRSMGRSATGVRGIRLR--
-GVIGASVLKPDSHVFVISEKGYGKQTAASEYPIKGRGGKGIKTVNVS-E-NGPLAGLTTLDD-EDIMLVTNKGVMIRFSGADVSETGRATLGVHLIRLN
D-AVATMAKVA-
>tr|D3SGL4|D3SGL4_THISK DNA topoisomerase (ATP-hydrolyzing) OS=Thioalkalivibrio sp. (strain K90mix) GN=TK90_2770 PE=4 SV=1
AADLIPEEDVMLIGTQQGYLKRIAAKDMNRQNRGT-G--SMS--DD-LVTTFHAGHSHDTLIALTDSGQVHAIKAYDIPDGL-GNKGRHYRNVF-EVG-N
V---MLTVDV---THSLVIFTAQGLVKRTPLSAYSR-G---IQGISLV--DSIVC---S---PNESVIADNAKAI------ARAIGRTSRGVRAMNLS--
DAVVAGDIIHAKAHLMVVSEKGLGKATPA-EFR-QSRGGKGVTSY---NKRSGPV-AATVLF-GADVVLFNDQGGANRIAG-DVPH-GR---GSAIIRNG
V-NVLAV---P-
>tr|A0A0K2BKS0|A0A0K2BKS0_9GAMM DNA gyrase subunit A OS=Candidatus Baumannia cicadellinicola GN=gyrA PE=3 SV=1
MEDIINKEDVVVTLSYQGYVKYQPLKDYEAQRRGGKGSAAR-MKEEDFIHSLLVANTHDTILLFSSLGRMYWMKVYQLPTASRGSRGRPIVNLLPLE-NE
RITTILPVRKYEEGLNIFMATASGTVKKTALTEFSRPRSTGIIAVNLHGGDELIGVNLTNGSNEVMLFSAYGKVVRFSESQVRSMGRTATGVRGINLA--
EGVVSLIVPRA-GHILTVTRHGYGKRTAQVEYPTKSRYTQGVISIKVSE-RNGEVVGAVQVNDNDQIMLITDAGTLVRTRVSEVSIFGRNTQGITIIRTA
EAHVVSLQRVA-
>tr|A0A088MYG6|A0A088MYG6_9GAMM DNA gyrase subunit A OS=Candidatus Baumannia cicadellinicola GN=gyrA PE=3 SV=1
IEDLINQEDVVVTLSYQGYVKYQPLNDYEAQRRGGKGSAA-RMKEKDFIHRLLVANTHDTILLFSSRGRMYWMKVYELPAASRGSRGRPIVNLLPLE-NE
RITTIL--P--EEGHNVFMATASGTVKKTSLIEFSR-RSAGIIAVNLHGGDELIGVDLTDGSNEVMLFSAYGKVVRFSENQVRSMGRAATGVRGINLT--
-GVVSLIIPRADGHILTVTRHGYGKRTVQAEYPTKSRSTQGVISI--SE-RNGEVVGAVQVD-SDQIMMITDAGTLVRTWVSEVSIIGRNTQGITLIRTA
-DHVVSLQRVA-
>tr|J0XZ07|J0XZ07_9SPHI DNA gyrase subunit A OS=Saprospira grandis DSM 2844 GN=gyrA PE=3 SV=1
IEDMIKNERVVVTISHLGYIKRTASSEYQTQSRGGRGSKAAAT-DKDFMEHLFVSNTHDYLLLFTQKGRCHWKRVYEIPEGSKSTKGRAIQNFVELPEDD
KVKAYIVLKK--DNHFLTFATRKGLVKKTALRAYSR-RSAGIHAITFKEGDELLEVKLTDGKSEIMLAASNGKAIRFS---VRSMGRTAAGVKGMNLE--
-VLIGMITFAEK-KIANISENGLGKCTELE-YRIQSRGGKGIKTMQLTE-KTGKLIAIKAVT-RDDLMIINKSGLTIRFMVEQLPINGRSTQGVKLINLK
-GAIADVALIK-
>tr|M5J7Y7|M5J7Y7_9LACO DNA gyrase subunit A OS=Lactobacillus saerimneri 30a GN=gyrA PE=3 SV=1
DEDLIEEENVVITVTHNGYVKRMPTSEFKAQNRGGRGIQGMNV-DDDFIEHLITASTHDVLLFFTNVGKVYRMKGYEIPEYGRAAKGIPIINLLDI-DEE
KIQAVIKVTQ-DAAHYLFFTTLHGRVKRTAVEEFAN-RRNGLKAINLRDGDELIKVV-TDG-QNIIIGTHNGYAVSFAE--VRSMGRTASGVLGVRLR--
-DVIGSAILDPKSNVLVVSEKGYGKQTPASEYGIKNRGVMGVKTLNIT-D-NGALAGLTTVKD-EDILVITTGGVMIRFKVADVSQTGRATLGVRLMKLD
D-QVSTMTKVE-
>tr|A0A0R2KIX7|A0A0R2KIX7_9LACO DNA gyrase subunit A OS=Lactobacillus ceti DSM 22408 GN=IV53_GL000029 PE=4 SV=1
DEDLIEEENITITLTHNGYIKRLATEELKAQNRGGRGIKGMGI-DDDFIEHLITASTHDELFFFTNVGKVYRMKGYEIPEYGRTAKGIPVINLLGI-EEE
KIQAVIKVTQ-DKEQYLFFTTLYGRVKRTSVAEFQN-RKNGLKAINLRDNDELIKVV-TDG-KNMIIGTHDGYAVSFPE--VREMGRSASGVRGVRLR--
-DIIGSAILEPENNVLVVSEKGYGKQTPASEYAVKSRGIKGVKTLNVT-D-NGKLAGLNSVNT-EDMLVITDAGVIIRFAVADVSQTGRATLGVRLMRLD
D-RVATMTKVE-
>tr|W0JAP2|W0JAP2_9BACT DNA gyrase subunit A OS=Opitutaceae bacterium TAV5 GN=gyrA PE=3 SV=1
MEDVIPNEGCVITVSHLGFIKRTPVADYRSQKRGGKGIIGTET-EEDFVEHLFTASTHDYIMFVTSSGQCLAKKVYDVPEGARTTKGKSVSSFLRLREGE
KIAAMLCFQ-F---RYLVMATKRGIVKKTPLSDYLGTHEGGLIGINLAEGDTVIGTVLTTGSDEIILVSHQGLAVRFRE-LFRPTGRATGGVTGMRFKD-
-QLDVIEVVDHSAKFLVASEAGLGVRTRFEDYRLINRGGRGVWAI--PD-NSINIAGALSVKDEDEIMLLTAKGQSVRCPVRDIREVNRGGKGVKLLTLA
-GKLLSIAKVV-
>tr|B5JQR1|B5JQR1_9BACT DNA gyrase subunit A OS=Verrucomicrobiae bacterium DG1235 GN=gyrA PE=3 SV=1
KADMTPKEGCFITISHKGFIKRVSDSEFRTQKRGGKGVQGGNT-EDDFVEHIFTANTHDTIMFFMNNGRVYVEKVYELPEGSRTSKGRSINNVLQLQKEE
QIAAMIC---IED-FNLVMCTKHGTVKKTNLAAYKNFRKGGIIGINIDEGDSLITVK-TNRDSELVIVTHLGKSIRFHE--LREQGRATRGVRGVKLS--
-DAQAME----ESALLICGINGQGKRTTFDEFPLQKRGGSGVIAA--A-----GVAGALAVRESDEIMMLTKNGQAVRTSVKDINLIGRITKGVRCINLN
-GVLLGIARIV-
>tr|R7LEW1|R7LEW1_9BACT DNA gyrase subunit A OS=Coraliomargarita sp. CAG:312 GN=gyrA PE=3 SV=1
MEDVIANEGCIISVSHNGFIKRTGVSAYRSQKRGGKGVIGSGQ-DEDFIEHIFTASTHDSIMFCMNNGRVYVQKVYEIPEGSRTSKGRSIKNVLDLKNDE
KVAAMICVK---DKHALIMATKKGVVKKTMLSEYKNCRKGGIIGINLDEGDDLIGVVLTEPESNVVLVTHEGMSIRFNE--LRAQGRSTRGVRGVTLK--
-DVKAIVVV--ASTLLIAGEMGQGKRSSYDEYRVQNRGGSGVIAI--HG-----VAGALSVRDDDEIMMFTQAGQAIRSPVKGIRVIGRTTQGVRLINLA
-GKLIGICKIV-
>tr|B1ZTK3|B1ZTK3_OPITP DNA gyrase subunit A OS=Opitutus terrae (strain DSM 11246 / PB90-1) GN=gyrA PE=3 SV=1
MEDVIPNEGCVITVSHLGFIKRTPVAEYRSQRRGGKGVIGAET-EEDFVANLFTASTHDYILFFTSIGQCHAKKVYDIPEGTRASKGKSVSSFLRLAEGE
KIAAMLCVK-F---RYLVTATKRGIIKKSALSDYANAREGGLIGINLQEADSVIGTVLTTGENELILVSHQGLAVRFRE-LFRATGRATGGVTGMRFKK-
-YLDVIEVVDHEAKFLVASEAGLGVRTRFEDYRLINRGGSGVWAI--PD-GSIKLAGALSVREDDEVMLLTAKGQSIRCPVKDIRETNRGAKGVRLVTLE
-GKLLSIARIV-
>tr|D5EPI4|D5EPI4_CORAD DNA gyrase subunit A OS=Coraliomargarita akajimensis (strain DSM 45221 / IAM 15411 / JCM 23193 / KCTC 12865) GN=gyrA PE=3 SV=1
MEDLVPNEGCMITVTHKGFIKRTSLDEYRSQKRGGKGVIGSGQ-EDDFVEHLFTASTHDYVMCFMNSGRVYVEKVYHIPEGSRTAKGRAMANVFELQEGE
KIAAMICVK---SAQSIVLATENGVTKKTKLSDFRNHRKGGIIGINIDEGDNLVGARLTSGEDDIILVTSNAQSIRFPE--LRDQGRNTRGVRGIKLK--
-DVVAIEIV--EAKLLIAGANGLGKRTEFSEYRQQSRGGSGIIAI--DK-----VAGALSVTDADEIMMFTLKGQAVRSPIDTVRVTGRAASGVKLVNLG
-KELIGISKVI-
>tr|A0A0R2XSQ8|A0A0R2XSQ8_9BACT DNA gyrase subunit A OS=Opitutaceae bacterium BACL24 MAG-120322-bin51 GN=ABS34_01635 PE=4 SV=1
MEDIIPNEGCMITITHKGFMKRTSLDEYRSQKRGGKGVIGSGQ-EEDFVEHLFTASTHDNIMFFMNSGRVYVEKVYNLPEGSRIAKGRALANILELQKGE
KIAAMICVD---SEQRIVLATEKGVTKKTMLSDYRNHRKGGLIGIKIDEGDNLIGARLTNGSNDIVLVTSNAQSIRFPE--LRDQGRATRGVRGIKLK--
-DVVAIEIV--GAKLLIAGANGLGKRTDFSDYRVQSRGGSGIIAI--DK-----VVGALSVTDEDEIMMFTKKGQAVRSPIADVRITGRAASGVKLVNLA
-RVLIGISRVV-
>tr|A0A0E3UJE5|A0A0E3UJE5_9BACT DNA gyrase subunit A OS=Verrucomicrobia bacterium IMCC26134 GN=gyrA PE=3 SV=1
MEDVIPNEGCVITISHAGFIKRTPSADYRSQKRGG-G--IAE--DD-FVEHLFTASTHDTILFVTSHGQCLAKKVYEIPEA-RTTKGKSVRSFI-SDG-E
K--STVCFP--AEDRYLVMATKMGTIKKTALADYANTR-AGLIGINLD--DIVIG---T---DELILVSHQGLAV-----LFRDTGRATAGVTGMRFRP-
SDLEVLEVVD-TSKFLVASQAGLGVRTRF-DYR-TARGANGVWAI---PENSINA-GALSIK-TDEIMLLTAKGQSVRCPV-TIRE-KR---GVKLLTLA
G-KLLSIAKIV-
>tr|A0A0J5PAX5|A0A0J5PAX5_9LACT DNA gyrase subunit A OS=Fructobacillus sp. EFB-N1 GN=gyrA PE=3 SV=1
DEDLIEEEDVIVTLTNNGYIKRVPASEFKAQNRGGRGVQGMNL-DEDFVDQLVNLSTHDSLFFFTNKGKVYRMKGYEIPEYGRQAKGIPVINLLNF-EDE
KIQTLLSVN--ESQDNLFFVTRKGVVKRTQVQDFAH-RTSGLKALTLRDDDEILKVL-TDG-QNIVIATMNGYSVTFAE--VRLMGRGAAGVRGINLR--
-GVIGADILTPDSKVFVISQKGYGKQTAATEYPVKGRGGKGIKTATIT-E-NGPLAGMVTVDD-EDIMVTTDQGVMIRFSVDTVSQTSRATQGVRLIRLE
D-KVATLTKLE-
>tr|A0A0K8MPM1|A0A0K8MPM1_9LACT DNA gyrase subunit A OS=Fructobacillus fructosus GN=gyrA PE=3 SV=1
DEDLIEEEDVIVTLTHNGYIKRVAASEFKAQNRGGRGVQGMNL-DEDFVAQLANLSTHDSLFFFTNKGKVYRMKGYEIPEYGRSAKGIPVINLLNF-DDE
AIQSLLTVHE--SEDNLFFVTRKGVVKRTKVQDFAN-RTSGLKALTLREDDEILKVL-TNG-QNIIIATHNGYSVTFAE--VRLMGRSAAGVRGINLR--
-GVVGADILVPDSKVLIITEKGYGKQTAAAEYPVKGRGGKGIKTATIT-E-NGPLAGMVTVDD-EDIMVTTNLGVMIRFSIADVSTTGRSTQGVRLIRLE
D-KVATFTKLE-
>tr|A0A0Q0Y5M1|A0A0Q0Y5M1_LEULA DNA gyrase subunit A OS=Leuconostoc lactis GN=AN225_08230 PE=4 SV=1
DEDLIEEEDVIITLTRNGYIKRVPQAEFKAQNRGGRGVQGMNV-DEDFVDQMVATSTHDTLLFFTNKGKVYRMKGYEVPEYGRQAKGIPVVNLLHF-EDE
KIQTVINVR--DSHDYLFFVTRLGVVKRTAVSEFAT-RTNGLKALTLHDDDEVLSVQ-TDG-QSVLIATKDGYSVRFVE--VRIMGRAAAGVRGIRLR--
-NVIGADVVDDTENVLVITEKGYGKQTPATEYPIKGRGGKGIKTANIT-D-NGVLAGMTIVRD-EDIMVTTTQGVMIRFAVASVSQTGRATLGVRLIRLE
G-KVATLAKVE-
>tr|Q040E4|Q040E4_LEUMM DNA gyrase subunit A OS=Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 / NCDO 523) GN=gyrA PE=3 SV=1
DEDLIEEEDVIVTLTNSGYIKRVATGEFKAQNRGGRGVQGMNV-DEDFVDQMISTSTHDTLLFFTNKGKVYRMKGYEVPEYGRQAKGIPVVNLLNF-ENE
KIQTVINVR--ESNDYLFFVTRLGVVKRTAVKEFAN-RTNGLKALTLHDDDEVLSVQ-TDG-QNIIIATHNGYSVSFAE--VRVMGRSAAGVRGIRLR--
-GVVGSDVLEKDHNVLIITEKGYGKQTPVSEYPIKGRGGKGIKTANIT-E-NGPLAGMTIVSQ-EDIMVTTTQGVMIRFNVDSVSQTGRATLGVRLIRLE
N-KVATLAKVE-
>tr|D5T1L2|D5T1L2_LEUKI DNA gyrase subunit A OS=Leuconostoc kimchii (strain IMSNU 11154 / KCTC 2386 / IH25) GN=gyrA PE=3 SV=1
DEDLIEEEDVIVTLTRNGYIKRVPQAEFKAQNRGGRGVQGMNV-DEDFVDQMVATSTHDTLLFFTNKGKVYRMKGYEVPEYGRQAKGIPVVNLLKF-EDE
KIQTVINVR--ESKDYLFFVTRLGVVKRTAVNEFSN-RTNGLRALTLRDDDEVLSVQ-TDG-QSILIATKDGYSVRFTE--VRIMGRSAAGVRGIRLR--
-GVVGSDVVNPNDNVLVITEKGYGKQTPVSEYPIKGRGGKGIKTVNIT-E-NGALAGMTIIHD-EDIMVTTTQGVMIRFTASSVSQTGRATLGVRLIRLE
G-KVATLAKVD-
>tr|H1WRI6|H1WRI6_LEUCI DNA gyrase subunit A OS=Leuconostoc citreum LBAE C10 GN=gyrA PE=3 SV=1
DEDLIEEEDVIVTLTRNGYIKRVPQAEFKAQNRGGRGVQGMNV-DEDFVDQMLATSTHDTLLFFTNKGKVYRMKGYEVPEYGRQAKGIPVVNLLNF-ENE
KIQAVISVR--ESKDYLFFVTRLGVVKRTAVSEFAN-RTNGLKALTLHDGDEVLSVQ-TNG-QSILIATQAGYSVRFAE--VRVMGRSAAGVRGIRLR--
-NVIGADVVTSSDNVLVITEKGFGKQTRASEYPIKGRGGKGIKTANIT-D-NGVLAGMTIIHH-EDIMVTTTQGVMIRFAADSVSQTGRATLGVRLIRLE
G-KVATLTKVD-
>tr|K0D800|K0D800_LEUCJ DNA gyrase subunit A OS=Leuconostoc carnosum (strain JB16) GN=gyrA PE=3 SV=1
DEDLIEEEAVIVTLTRNGYIKRVPQAEFKAQNRGGRGVQGMNV-DEDFVDQMIATSTHDTLLFFTNKGKVYRMKGYEVPEYGRQAKGIPVVNLLNF-EDE
KIQTVITVK--ESQDYLFFVTRQGVVKRTAVSEFSN-RTNGLKALTLRDNDEVLSVQ-TDG-QSIIIATKDGYSVRFSE--VRIMGRAAAGVRGIRLR--
-GVIGSDVLSQQDNVLIITENGYGKQTPATEYPIKGRGGKGIKTANIT-E-NGSLAGMIIINN-KDIMVTTTQGVMIRFAASTVSQTGRATMGVRLIRLE
G-QVATLAKVD-
>tr|A6DH72|A6DH72_9BACT DNA gyrase subunit A OS=Lentisphaera araneosa HTCC2155 GN=gyrA PE=3 SV=1
YEDLIARASATITISNEGYIKRVPTEIYRTQNRGGKGVKGMET-DDDFVKQLTTACTHDYIMFFTNFGRMHWLKVYDIPEATRVSKGKAMVNLLEFEKGE
YVRAMISVD-V--DRFIMMSTRNGVVKKTALAAFKNMRKKPIKAIVLDEDDDLIEAKLTDGNKKIILSTREGIACHFKE--CRTQGRVTRGCRGIRLS--
-QVVAMSIVEESEDILVVTAKGMGKRSCVDDYRLTKRGAKGVRNI--KE-G-DYVVEVMMIEDTDEIIMTTMEGLMVRISAEPIRSLGRASQGVTIMKFK
-ADLIISARVV-
>tr|A0A0A2DT26|A0A0A2DT26_9PORP DNA gyrase subunit A OS=Porphyromonas sp. COT-239 OH1446 GN=gyrA PE=3 SV=1
PEDFYADEEMIITISHHGYIKRTPLSEFRSQARGGVGAKGSDT-DEDFIEYIYSASMHATMLLFTQRGRCYWLKVYEIPEGSKSAKGRAIQNLLNIEPGD
KVNAFIRIKT--NSHYLIFCTKRGIIKKTLLEAYSR-RTSGVIAINLSEDDSLVSVSLTNGKAELLVANRNGRAVRFH---VRAIGRQGMGVKGMTLDDG
-DVIGMISIRDQESVLVVSEKGYGKRSKI-DYRITNRGGKGVKTLNITD-KTGLLVAVRSVT-EHDLMIINKSGIAIRLRARDLAIIGRATQGVRLINLD
RGEIASVCRVI-
>tr|A0A0A2FG19|A0A0A2FG19_9PORP DNA gyrase subunit A OS=Porphyromonas crevioricanis GN=gyrA PE=3 SV=1
PEDFYADDEMIITLSHMGYIKRTPLTEFRTQSRGGVGAKGSDT-SEDFVEYIYSASMHATILLFTAKGKCYWLKVYEIPEGAKNAKGRAIQNLLNIDPDD
KVTAFIRIKT--NSHYLMFATKTGMVKKTLLEAYSR-RTNGVIAINLNEGDEVVSVRLTNGRNQILIANRNGRAVRFD---VRTVGRNSIGVRGMRLDDG
-DVIGMIAIK-EQTVLVVSEHGYGKRSSIEDYRTTNRGGKGVKTMQVTD-KTGHLIDIRAVE-DNDLMIINKSGVAIRISVKDIAVIGRATQGVRLINLD
RGDIASVCSVI-
>tr|A0A0A2E7S9|A0A0A2E7S9_9PORP DNA gyrase subunit A OS=Porphyromonas macacae GN=gyrA PE=3 SV=1
PEDFYADDQMIITLSHMGYIKRTPLSEFRAQGRGGVGSRGADT-SEDFVEFIYNASMHATLIFFTEQGKCYWLKVYQIPEGSRTGKGRAIQNLLNLDANN
RVNAIVWVKT--NTHYLVFCTKQGLVKKTPLEAYSR-RANGVIAIGLREGDQVVSVRLTNGRNELVIANRNGRAIRFS---IRPSGRPSMGVRGITLDDG
-DVIGMVAIK-EETILVISEKGYGKRSHVEDYRVTNRSGKGVKTLNITE-KTGNLVDIRSVT-DQGLMIINKSGVTIRLNVEELPVIGRATQGVRLINLE
RDEIASVCGVA-
>tr|Q7MUU5|Q7MUU5_PORGI DNA gyrase subunit A OS=Porphyromonas gingivalis (strain ATCC BAA-308 / W83) GN=gyrA PE=3 SV=1
PEDFYADDDMIITLSHMGYIKRTPLSEFRTQARGGVGAKGSDT-EEDFVEYIYSASMHATIMLFTAKGRCYWLKVYEIPEGAKNAKGRAIQNLLNIDPDD
KVNAFIRIKT--NSHYLLFCTKRGIIKKTLLEAFSR-RANGVIAIDLRDNDGLVSVRLTNGKCDMVIANRGGRAIRFH---VRPSGRTAMGVKGMTLDDG
-DVVGMISIK-EETILVVSEKGYGKRSNIDDYRITNRGGKGVKTLNITE-KTGKLVDIRAVT-ANDLMIINKSGVAIRVKVADLSIIGRATQGVKLIDLS
RGEIASVCSVV-
>tr|A0A0A2F8S2|A0A0A2F8S2_9PORP DNA gyrase subunit A OS=Porphyromonas sp. COT-290 OH860 GN=gyrA PE=3 SV=1
PEDFYADDEMVITISHLGYIKRTPLSEFRTQSRGGVGSKGSDT-DEDFIEYIYSASMHATMLLFTQMGRCYWLKVYEIPEGAKNAKGRAIQNLLNIEPGD
RVTAFIRIKT--KSHYLFFATKRGVVKKTLLEAYSR-RTTGIIAINLLEGDELVGVALTNGRSEIVLANRNGRAVRFN---VRHTGRTATGVRGMILDDG
-DVIGMLAVK-KESILVVSEHGFGKRSNVEDYRITNRGTKGVKTLNITD-RTGVLVAIRSVT-EHDLMIINRSGVTIRVHARDLSIIGRNTQGVRIINLD
RGEIASVCRVM-
>tr|A0A0D3VGA9|A0A0D3VGA9_9BACL DNA gyrase subunit A OS=Paenibacillus sp. IHBB 10380 GN=gyrA PE=3 SV=1
DEDLIPQEEVIITISHTGYIKRLPANTYRSQKRGGRGVMGMDT-DLDFVEHLFVTNSHHYLLFFTDRGKVYRLKAYEIPELSRTARGTAIINLIQIEQ-E
TVNAVIPVQ---GEDYLFFATRQGVVKKTPLEDYIN-RKGGLIAINLRDDDALIGVK-TDG-QEVIMGTAQGMSIRFSE--VRSMGRSATGVKGIRLS--
-EVIGMDVVDKDLDILIVTSKGYGKRTPVSDYRSQSRGGKGIKTINVT-D-NGPVIALKVVKE-EDLMIITTSGTLIRTSMEGISTMGRYTQGVKLINTR
D-AVATVCRVD-
>tr|D5WQZ8|D5WQZ8_KYRT2 DNA gyrase subunit A OS=Kyrpidia tusciae (strain DSM 2912 / NBRC 15312 / T2) GN=gyrA PE=3 SV=1
DEDLIPMEEVAVTLSHDGYIKRQPMSLYKSQRRGGRGITAMGT-EEDFVEHLFITSSHHYLLFFTNKGKVYRLKAYEVPELGRAAKGTPIVNLLNVDQ-E
KISAVVPIR---GGQYLIMATREGTIKKTPLDEFEN-RRGGLVAISLRENDELIAVR-TDG-RELILGTRSGMAIRFPE--VRSMGRGAAGVKAVDLQ--
-GVIDMDVVDPDGDVLVVTNRGFGKRTPITEYRHQSRGGKGIRTLHVT-A-TGSVVSLKMVRD-EDVMVITTTGIAIRMHVDEISVQGRNTQGVKLITLK
D-EVSTVAKVV-
>tr|R6QRT9|R6QRT9_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:352 GN=gyrA PE=3 SV=1
IEDLIPEEDCVLTLTEFGYIKRQKSDTYKLQRRGGRGVSGMSR-EEDVAKEMFVANSHDHVMFFTNLGRVYKLKCYEIPE-SRTSKGMNINNLLPLSADE
SVTSMIKVP-IS-EQYLVMVTRNGIIKRTELSAFSHARKNGLIAIDLNEGDELAWVRLTDGNKELVVATRNGMAIRFH---VRVMGRAAKGVKAITLR--
-KVIGMSMLR-GAYILTVSETGYGRLSNVSDYRIQSRGGHGVINYNTD--KYGKVAAIKSVD-DDDIILISNDGVIIRIEANSIRI-SRTSKGVRVMKVS
DEKVVTLSRAP-
>tr|R6GPH3|R6GPH3_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:557 GN=gyrA PE=3 SV=1
IEDLIPEEDCVLTLTNFGYVKRQKTDTYKLQRRGGRGISGMSC-EEDVAAEMFVVNSHDYVMFFTNFGKVYRLKCYEIPE-SRVSKGTNVANLLPIMPDE
KVTSMIKVP-FG-EKYLVMVTKSGVIKRTLLSAYDSARKGGLIAIDLDDGDELAWVSVTDGATELLVATKKGMAIRFN---VRAVGRTARGVKAISLR--
-NVVGMSPVS-ETMVLTVSETGYGRLSEIDDYRLQMRGGKGITNYHVE--KYGDVASIKLVS-DEDIILISESGIIIRIKADTIRV-SRPSKGVRVMKIA
DNRIVAVASVP-
>tr|R6V5X3|R6V5X3_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:964 GN=gyrA PE=3 SV=1
IEDLIPQEECVLTMTRFGYVKRLSVDTYHTQKRGGKGVSGMSR-EEDVASDMFVINSHDYVLFFTNFGRVYRLKCYEIPES-RTSKGMNIANLLPIAPEE
KVTSVIKVP-F-DEKYLIMVTKQGLVKRIKLSAYNTNRKGGVVALELNEGDELAWVRMTDGSSQVVVATRLGKAIRFD---VRPMGRTARGVKALTLL--
-YVIGMTTVN-DDMILTVSEAGYGRLSNVSDYRLQSRGGKGIINYHTEK--YGNVAAISAVD-NDDIIIISSDGVIIRIEASSIRI-SRPSKGVTVMRVN
-EKVVTLAVAP-
>tr|R6NA01|R6NA01_9CLOT DNA gyrase subunit A OS=Clostridium leptum CAG:27 GN=gyrA PE=3 SV=1
IEDLIPQEECVLTLTNFGYVKRQKMDTYRTQRRGGRGISGMSR-EEDVATEMFVINSHDYVMFFTSTGRVYRLKCYEIPE-SRTSKGMNIANLLPITAEE
KVTSMIRVP-FE-EKYLVMVTRNGIIKRTLLSAYNSARKGGLIAIELDEGDELAWVRVTDGSNELIVATKKGMAIRFH---VRLVGRTARGVKAITLG--
-CVVGMARLR-GGKVLTVSETGYGRLSPISDYRIQYRGGKGLLNYHVD--KYGDVAAIKVVD-DDDVILISADGVIIRIQADSIRE-ARPSKGVRVMRIG
EDKVVTLARAP-
>tr|E6U5D1|E6U5D1_ETHHY DNA gyrase subunit A OS=Ethanoligenens harbinense (strain DSM 18485 / JCM 12961 / CGMCC 1.5033 / YUAN-3) GN=gyrA PE=3 SV=1
VEDLIPVEDVVLTLTNFGYIKRLPAAAYHSQRRGGRGVNGLTR-EEDVARELFVCSTHDFVLFFTSHGRCYRLKGYEVPE-SRTSKGMNVANILPVAQDE
NITAMIKVP-FE-DCYLVMVTKKGIVKRTSLKEYDTARKAGVIGILLEEDDELVGVLLTDGSAHILVGTRNGVAIRFV---ARPMGRAAHGVKAISLE--
-YVVGVTVPN-AGSLLLITENGYGKRVPFEDFRVQNRGGKGLTSYNINE-KTGPVAGLRVVE-SDDALFISSDGVVIRVPVAEIPV-SRYAQGVRVMRVG
EEKVVTVTSAA-
>tr|R6NVI1|R6NVI1_9FIRM DNA gyrase subunit A OS=Eubacterium sp. CAG:202 GN=gyrA PE=3 SV=1
IEDLIPNQECVLTLTQFGYVKRLAVDTYKIQNRGGRGVSGMSR-EEDVATEMFVINSHDYVLFFTDKGRVYRLKCYEVPE-SRQSKGMNIANLLPIAADE
KVTSMIRVP-FE-EKYLVMVTKQGIIKRISLNAYNTARKGGLIALELNEGDELAWVRLTDGNQQVIVATKNGLAIRFE---VRPMGRQARGVKAISLR--
-CVVGMCVVA-DDLILTASETGFGRISNVSDYRLQSRGGKGITNYHTE--KYGNVAAVSAVK-NEDIIIISQEGVIIRIAADTVRI-NRPSKGVTLMRIG
ENKVVTVARAP-
>tr|J0WSD1|J0WSD1_9CLOT DNA gyrase subunit A OS=Clostridium sp. MSTE9 GN=gyrA PE=3 SV=1
IEDLIPQEECVLTMTNFGYVKRQKVDTYHIQRRGGRGVSGMTR-EEDVATEMFIINSHDYVLFFSNLGRVYRLKCYEVPE-SRTSKGINIANLLPLSSGE
SVTSMVRVP-FE-ESYLVMVTKNGIIKRTVLSAYNTARKGGVIAIDLDEGDSLSWVRRTDGNREMLVATKKGMSIRFR---VRAMGRTARGVKAITLK--
-CVTGLSTIR-GGLVLTVSETGYGRLSPITDYRTQSRGGKGLLNYHVE--KYGDVASIKVVD-DDDVIIISSDGVIIRIHAASIRV-ARPSKGVRVMRVN
VERVVTLARAP-
>tr|D4L5T3|D4L5T3_9FIRM DNA gyrase subunit A OS=Ruminococcus bromii L2-63 GN=gyrA PE=3 SV=1
IEDLIPQEECVLTLTQFGYVKRLSADTYKIQRRGGRGVSGMSR-EEDIAAEMFVINSHDYVLFFTDKGRVYRLKCYEVPES-RQSKGVNIANLIPISPDE
KVTSMIRVP-F-EEKYLVMVTRQGIIKRIELNAYNTSRKGGLIALELNEGDELAWVRMTDGNSQVIIATKKGMAIRFN---IRAMGRQARGVKAMALK--
-CVVGMSVVR-GGLVLTVSETGYGRLSSPDDYRVQSRGGKGLTNYHTEK--YGDVAAIKVVN-D-DIIIISEEGIIIRIAAESIRV-ARPSKGVTVMKVN
-DRVVTIARVP-
>tr|R5QF75|R5QF75_9FIRM DNA gyrase subunit A OS=Ruminococcus sp. CAG:724 GN=gyrA PE=3 SV=1
LEDLIERHSCVITATRGGYFKRMPAREYTAQRRGGKGIIGMKT-DEDDVVDVMVVNSHSFLLMFTNKGKVFAKKAYMIPEG-RTAKGTNIVNLLELTEGE
FVTSVISID-F--NEYFVMVTKYGVIKRANVMDFEFMRRGGKIAMNLDEGDELLYVRKTAGESDIIIATREGKAVRFN---ARVMGRTARGVRGIRLR--
-YVVGAEVIDDSKKLITITQKGYGKKSDFEGFT-HSRGTMGVICHKISE-KTGYLAGIAAVC-TDDLMIITDEGVIIRTPAADIP-YGNNTAGVIVMRLS
--SVVNFTLVH-
>tr|R5GFY2|R5GFY2_9PORP DNA gyrase subunit A OS=Porphyromonas sp. CAG:1061 GN=gyrA PE=3 SV=1
PEDFYADEDMVITISHMGYIKRTPLADFHAQSRGGVGAKGSDT-DEDFVEYIYSASMHATLLFFTEQGRCYWLRVFEIPEGARNSKGRAIQNLLNLDADN
RVNAVLRVKT--NTHYLTFFTKSGLVRKSRLKDFSR-RQSGIIAIKLRDDDKVVSVMLSNGKCDFVLGSRKGRAVRFS---LRPLGRSSMGVRGMRLEDG
-ELVGAVCIK-EETILVISENGYGKRSSLEDYPLRNRGGKGVITLKITE-KTGELVSIHSVT-AHDIMIINKSGVAIRTSMKDISVIGRNTQGVKLINLS
RGEIASTCRVL-
>tr|A0A0A2DVY1|A0A0A2DVY1_9PORP DNA gyrase subunit A OS=Porphyromonas sp. COT-108 OH1349 GN=gyrA PE=3 SV=1
PEDFYADEEMVITLSHLGYIKRTPLAAFRQQGRGGVGAKGSET-DEDFVEYIYSASMHATMLFFTEKGKCFWLPVYEIPEGSRQAKGRAVQNLLNIDPDD
KISACIRVKT--RSHYITFVTQNGTVRKTSLEAFSR-RANGIIAIKLVEDDKVVSVLLSNGDCQFLIASRNGKAVRFH---VRPLGRNSIGVRGIRLDDG
-DVVGAICVK-SESILVVSENGFGKRSVIEDYRQTNRGTKGVLTLKVTP-KTGKLVSMKNVT-DNDLMIINKSGIVIRISVDSISMLSRNTQGVKLINLQ
NGEIASVTVVE-
>tr|A0A0A2EN83|A0A0A2EN83_PORCN DNA gyrase subunit A OS=Porphyromonas cangingivalis GN=gyrA PE=3 SV=1
PEDFYADEEMIITLSHLGYIKRTPLSAFRAQSRGGVGSKGTDT-DEDFVEYIYSASMHATMLFFTEKGRCFWLRVFEIPEGTRTSKGRAIQNILNLDPDD
RVTTCIRIKT--NSHYLTFVTRRGTIRKTLLEAFSR-RANGIIAIGLRDEDRVVSVLLSNGKSEFILASRNGKAIRFH---LRPQGRQTMGVRGMRLEDG
-DVIGAICIK-EESILVVSENGYGKRSQIDDYRITNRGAKGVITLKVTD-KTGDLIEIKNVT-EHDIMIINKSGVTIRTHVKDISVQSRNTQGVRLINLE
RGEIASVCRVQ-
>tr|A0A0E4GCU6|A0A0E4GCU6_9FIRM DNA gyrase subunit A OS=Syntrophomonas zehnderi OL-4 GN=gyrA PE=3 SV=1
EEDFIEDHEVVITLSNRGYIKRQPLDTYKAQKRGGKGVSSTST-AEDFALDVLVTGVLNNILFFTNQGRVFCSKAYHIPE-SRQAKGQTLVNFMELRPEE
KVSTIISVK-FE-KRHLLMVTRKGTVKKVALDSFSNIRKSGLIAINLADDDELVDVLRVEKDDRIMLVTSFGQSISFL---VRPMGRTAAGVKGINLG--
-FVIGADKYR-EAEAVLVTVNGYGKRTRLEEFNLQNRGGKGLKTIDVNN-KNGPVVGFKIVK-DEELVILTSEGQIIRLETEDIST-KRYSRGVVVMRIG
EGSIAAVARFK-
>tr|E0S2D5|E0S2D5_BUTPB DNA gyrase subunit A OS=Butyrivibrio proteoclasticus (strain ATCC 51982 / DSM 14932 / B316) GN=gyrA PE=3 SV=1
TEDLIPNVNTVIAMTSLGYIKRMSIDNFKAQNRGGKGIKGITT-DNDYVEDILMTTTHNYVMFFTNTGRVYRLKAYQIPES-RTSRGMAIVNLLQLAPGE
KISAMIPVK-F-EEKCLFMVTKKGTVKKTPITDFSNVRKTGLAAITLRDDDELIEVKTVTKDAEVFLVTKNGMCIHFD---VRITSRSSIGVRGMMLD--
-EIVGMQLNTQGDSLLIVSEKGYGKRTTLDEFH-QFRGGKGVKCYKITE-KTGNVIGVKAVN-DNEIMMITNAGIIIQLRMDEIT-HGRVTSGVKMINLD
-GTVAKIAKVR-
>tr|R5CL61|R5CL61_9FIRM DNA gyrase subunit A OS=Firmicutes bacterium CAG:791 GN=gyrA PE=3 SV=1
MEDLIQNENCVITRTSLGYIKRTSADEFRAQNRGGRGVKGAHT-DDDYVEDLLMTAIKDTLLIFTTKGRVYKLKTYKIPEASRTSRGTAIVNLLQLDA-E
KVSALIPVQ---DDKSLFMVTRNGIVKKTRCREFAN-RSNGINAIAIQDGDALIEVK-TCA-DDIIIVTKKGMSVRFHE--VRATGRSSMGVMGIRLD--
-NVAGMQLSSQGDSILVVSEKGMGKRSSLEDFRVQNRGGKGIKCYKIT-E-TGDVVGVKAVND-HEIMMITSAGIIIQIRMNEVPVHGRITSGVKLINLE
G-KVVKIAKVR-
>tr|A0A068N1Y9|A0A068N1Y9_SYNY4 DNA gyrase subunit A OS=Synechocystis sp. (strain PCC 6714) GN=gyrA PE=3 SV=1
DTDLIANDQALILLTEQGYIKRMPASTFGTQNRATRGKAAAKI-EDDGVEHFLSCCDHDKVLFFSDRGVVYSLNAYQIPIASRTARGVPIVQMLPIPKDE
KITSLVSVS---DDTYFIMLTKQGYIKKTALSAFSNIRANGLISISLVEGDQLRWVRLAKAEDSVIIGSQKGMAIHFKA--LRALGRATRGVKSMRLR--
-ALISMDILPSGPWLLGVTMKGFGKRVPIGQFRLQHRAGLGVKAIRF--K-DDQLVALHVVN-DDELMIVTNRGIIIRQSVNDISPQSRSATGVRVQRLD
-DAIAAVALVP-
>tr|A0A0H3K8X7|A0A0H3K8X7_SYNP6 DNA gyrase subunit A OS=Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1) GN=gyrA PE=3 SV=1
TIDLIANEKSILLLTQQGYIKRMPVNEFTAQSRGTRGKAGAKT-DDDSVEHFLTCCDHDNILFFSDRGVVYNLPAYRIPAASRNARGVPIVQLLPIPREE
RITSIVPVS---DDEYLVMLTQGGYIKKTALSAFANIRSNGLIAIALSEGDQLRWVRLAKPEDSILIGSRKGMTIHFRA--LRPLGRATRGVRAMSLR--
-TLISMDVLPAGPWVLVVTAQGLGKRVPVHQFRLQKRAGLGLRAIKF--K-QDELVSLRIVE-GDELVMISQRSVIIRQASDAIPQQSRAATGVRVQRLD
-DVLAAVALVP-
>tr|Q608R9|Q608R9_METCA DNA gyrase subunit A OS=Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath) GN=gyrA PE=3 SV=1
AEDLITEEDMVVTVSHEGYVKAQPLSDYRAQRRGGRGQAAA-TKEEDYIEKLVVANTHDTILCFSSSGKVYWLKVYELPVASRTARGRPFVNLLPLE-GE
RINAILPIREFDEAHFIFMATASGTVKKVALSEFERPRPSGKIAIELRDDDRLVDVAITNGEQDVMLFSSDGKVVCFHETDVRAMGRTAAGVRGMTLQER
K-VIALIIAS-EGTVLNITENGYGKRTRLEEFPRHRRGGQGVIAIQTSA-RNGAVVGAALVEDEDEIMLITDAGTLVRTRVSEISVLSRNTQGVTVIRLN
PGKVVGMDRIG-
>tr|C7DIB2|C7DIB2_MICA2 DNA gyrase subunit A OS=Candidatus Micrarchaeum acidiphilum ARMAN-2 GN=gyrA PE=3 SV=1
NEDLIKDEDSIIILTKDGYMKRLPMDVYKNQGRGGRGVISIDL-EGDFVKQVVRCMTKDYLLVITSAGRVYWLKGYVVPEGGRYAQGKAAVNLISIAEGE
RIEQIINTR---SGKNLIFATRRGRIKSTKAELFSRPRANGIRAIKLNEDDIVVGVCLSTGGSNVFLATRNGKAIRFME--LRHMGRVASGVRGIRLK--
-ELVDVV--VAKKNIITITERGYGKATLLERYRLQRRGGGGVINL--TE-KTGKVVRVLDGEQDDNVIIFNSKGLSIRFNANAIRVTGRNASGVRLMKLE
-DKVVDAQIVG-
>tr|D5BWP7|D5BWP7_NITHN DNA gyrase subunit A OS=Nitrosococcus halophilus (strain Nc4) GN=gyrA PE=3 SV=1
LEDLIQEENVVVTLSHTGYAKYQALDAYRSQKRGGKGSATA-MKEEDFIDKLFIANTHDTLLCFSSRGKVYWKKVYELPQGTRTARGKPIVNLLPLE-GE
RINTVLPIREFEEGKYVFMVTASGVVKKTSLAVFSRPRPSGIIALELREGDQLVGADLTDGEQEIMLFSSGGKVIRFSEQKVRPMGRTARGVKGMELPPH
R-VIALIIAR-NGTILTATELGYGKRTAIAEYRLQGRGGQGIISIQTTP-RNGQVVGAVQVEEEDEIVLITNRGTLIRTPVCDISLMGRNTQGVKLINLL
EGRLVGVERIV-
>tr|S2D9N1|S2D9N1_9BACT DNA gyrase subunit A OS=Indibacter alkaliphilus LW1 GN=gyrA PE=3 SV=1
YEDMIPNEEVIITVSHQGYVKRTLLAEYRTQGRGGVGSKGVST-EDDWTEYLFTASTHNYLLIFTDHGKLFWLKTYAIPEGSKTSKGRPIQNLINIEAED
KIRSIIQVAD--NNHFLVMVTKQGIIKKTTLEQYSR-RSNGIIALNIREDDQLLRVDMTNGDSHIIIAAKSGRAIHFH---VRPMGRTATGVKAIKLSV-
-DVVGMVCASRDANLLVVSEKGYGKRSPLDEYRITNRGGKGVKAMNVTE-KTGSLVAIKEVV-SDDLMIINKSGITIRTPVANLRVMGRATQGVRLIKLS
-NQISSVEKIE-
>tr|A0A0P7XRG0|A0A0P7XRG0_9BACT DNA gyrase, A subunit OS=Algoriphagus marincola HL-49 GN=gyrA PE=4 SV=1
YEDMIPNEEVIITVSHQGYIKRTALTEYRTQGRGGVGSRGVST-EDDFTEYLFTASTHNYLLIFTDQGKLFWLKTYAIPEGGKTSKGRPIQNLINIASDD
RIRAIIQVNN--NNHFLIMVTKKGIIKKTTLEQYSR-RTNGIIALNIREDDQLVNVDMTNGDQHIVIAAKSGRAIHFH---VRPMGRTATGVKAITLNV-
-DVVGMVCASENATLLVVSEKGYGKRSFLEEYRITNRGGKGVKAMNTTE-KTGALVAIKQVV-TDDLMIINKSGITIRISVDGLRIMGRATQGVRLIKIS
-GEISSVEKIS-
>tr|L0G3A1|L0G3A1_ECHVK DNA gyrase subunit A OS=Echinicola vietnamensis (strain DSM 17526 / LMG 23754 / KMM 6221) GN=gyrA PE=3 SV=1
YEDMIPNEEVIITVSHQGYVKRTALKEYRTQGRGGVGSRGVST-DDDYTEYLFSASTHNYLLIFTDKGKLFWLKTYAIPEGSKTSKGRPIQNLINIESDD
KIRSIIQVTN--QNNFLVMVTKNGVIKKTTLEQYSR-RSNGIIALNIREDDQLLNVEFTHGDSHILIAAKSGRAIHFH---VRPMGRTATGVKAITLSD-
-DVVGMVCVNREATLLVVSEKGYGKRSAVEEYRITNRGGKGVKAMNVTD-KTGSLVAIKSVI-SDDLMIINKSGIIIRTPVSGLRIMGRATQGVRLIKLN
-NEISSVAKVE-
>tr|I3Z7I4|I3Z7I4_BELBD DNA gyrase subunit A OS=Belliella baltica (strain DSM 15883 / CIP 108006 / LMG 21964 / BA134) GN=gyrA PE=3 SV=1
YEDMIPNEEVVITVSHEGYIKRTALSEYRTQSRGGVGSRGATT-DDDWTEYLFTASTHNYLLIFTDLGKLFWLKTYAIPEGSKASKGRPIQNLINITSED
SIRSIIQVES--NNNFLVMVTKKGIIKKTTLEQYSR-RTNGIIALNIRDEDQLMQVEMTNGNSHIIIAAQSGRAIHFH---VRPMGRTATGVKAIKLSV-
-DVIGMVCASRDASLLVVSEKGYGKRSPLDEYRITNRGGKGVKAMNVTE-KTGYLVAIKEVV-TDDLMIINKSGITIRTPVSNLRVMGRATQGVRLIKLG
-NEISSVEKIR-
>tr|R7ZW75|R7ZW75_9BACT DNA gyrase subunit A OS=Cyclobacteriaceae bacterium AK24 GN=gyrA PE=3 SV=1
YEDMIPNEEVVITVSHQGYIKRTVLTEYKTQSRGGVGSKGVTT-EDDFTEYLFTAMTHNYLLIFTDQGKLFWLKTYAIPEGGKTSKGRPIQNLMNIESGD
KIRSIIQVSN--NNNYIVMITKNGIIKKTTLEQYSR-RTNGIIALNIRDEDQLVNVELTNGDSHIVIAASSGRAVHFH---VRPMGRTATGVKAINLEG-
-YVIGMVCVSRDATLLVVSEKGYGKRSYLSEYRVTNRGGKGVKAMNVTE-KTGGLVAIKEVV-SDDLMIINKSGIAIRTPVSGVRVMGRATQGVKLIRLN
-NEISSIEKIE-
>tr|A0A0H4PYQ3|A0A0H4PYQ3_9BACT DNA gyrase subunit A OS=Cyclobacterium amurskyense GN=gyrA PE=3 SV=1
YEDMIPNEEVVITVSNQGYIKRTVLTEYKSQSRGGVGSRGVST-EDDYTVYLFTALTHNYLLIFTDQGKLFWLKTYAIPEGSKTSKGRPIQNLINIESSD
RIRSIIQVKG--NNNNIVMVTKKGIIKKTTLEQYSR-RTNGIIALNIREDDQLLNVELTNGDANIVIASSSGRAVHFH---VRPMGRTATGVKAINLGD-
-NVIGMVCVQRDATLLVVTDKGYGKRSYLSEYRITNRGGKGVKAMNITE-KTGGLVAIKEVV-TDDLMIINRSGITIRTPAEGIRVMGRATQGVRLIRLN
-TEISSVEKIE-
>tr|U5C452|U5C452_9BACT DNA gyrase subunit A OS=Rhodonellum psychrophilum GCM71 = DSM 17998 GN=gyrA PE=3 SV=1
YEDMIPNEEVVITVSHEGYVKRTALTEYKTQGRGGVGSKGATT-LDDWTEYLFTASTHNYLLIFTDLGKLFWLKTYAIPEGAKASRGRPIQNLIQIESND
KIRSIIQVGN--NNNFLVMVTKQGIIKKTTLEQYSR-RSNGIIALNIREDDQLIQVEMTNGDSHILIAAKSGRAIHFH---VRPMGRTATGVKAIKLSV-
-DVIGMVCADSETSLLVVSEKGYGKRSPLGEYRITNRGGKGVKAMNVTE-KTGSLVAIKQVM-SDDLMIINKSGITIRTPVSELRIMGRATQGVRLIKLG
-NEISSVEKIK-
>tr|I5C7N6|I5C7N6_9BACT DNA gyrase subunit A OS=Nitritalea halalkaliphila LW7 GN=gyrA PE=3 SV=1
YEDMIPNEEVVITVSHQGYVKRTALTEYRTQSRGGVGSKGVST-EDDWTEYIFSASTHNYLLIFTDLGKLFWLKAYAIPEGSKTAKGRPIQNLINISADD
KIRSIIQVAE--KNNFLIMVTKEGVIKKTSLELYAR-RTNGIIALNIREGDQLIRVEKTNGDSHVIIAAKSGRAIHFH---VRPMGRTATGVKAISLQE-
-DVIGMVCAEREATLLVVSEKGYGKRTLLDAYRITNRGGKGVKAMSVTE-KTGNLVAIKEVV-SDDLMIINKSGITIRTPVSDLRVMGRATQGVRLIKLS
-TEISSVEKIT-
>tr|A0A074LJL8|A0A074LJL8_9BACT DNA gyrase subunit A OS=Anditalea andensis GN=gyrA PE=3 SV=1
YEDMIPNEEVIITVSHQGYIKRTVLTEYRTQSRGGVGARGVST-QDDFTEYLFTASTHNYLLIFTDKGKLFWLKTYAIPEGGKTSKGRPIQNLINIESDD
KIRSIIQVAG--NNNFLVMVTKQGIIKKTTLEQYSR-RTNGIIALNIREDDQLINVEMTNGDTHIIIAAKSGRAIHFH---VRPMGRTATGVKAMKLAE-
-DVVGMVCALRDATLLVVSEKGYGKRSALDAYRITNRGGKGVKAMNVTE-KTGSLVAIKEVV-SDDLMIINKSGITIRTPVADLRVMGRATQGVRLIKLS
-TEISSIEKIE-
>tr|A0A0K6IXK1|A0A0K6IXK1_9PROT DNA gyrase subunit A OS=Tepidiphilus thermophilus GN=gyrA PE=3 SV=1
LEDLVAPQDMVVTLSHAGYVKRQPLDDYRAQRRGGRGQAAA-VKEEDFLEQVFVANTHDWVLCFSSRGRVYWLRVFELPEGARGARGKPIVNLVPMG-DE
RIQAVLPVREF--AHYVFFATASGVVKKTALSAFANPRKAGIVALSLDDGDRLIGVDLTDGTCDVMLFSDAGKAVRFAE-DVRPMGREARGVRGMALE--
DGVVSMLVVRDSGSVLTATEAGYGKRTPVAEFTRHGRGTKGMIAIQTSR-RNGRLVAACLVQPGDEIILISQNGVLIRTSVDDIREMGRSTQGVTLMALD
DGRLVTVVKVA-
>tr|F8A8K9|F8A8K9_THEID DNA gyrase subunit A OS=Thermodesulfatator indicus (strain DSM 15286 / JCM 11887 / CIR29812) GN=gyrA PE=3 SV=1
VEDLIAEEEVVVTITHRGYIKRLPANTYRSQRRGGKGKTGVGA-EEDVVTQLYVATTHDYFLCFTNKGKLYWLKVYDIPQAGRTAKGTSLRNLLPLSQ-E
KIATILPVK----DQFVFFATKKGLVKKTSLSAFSH-RNTGIVAAVVKDGDELMAAG-TDG-KEILLVTRKGQSIRFSE--VRPMGRTAAGVKGIELT--
DEVVSLEILDPEASLLTVTELGYGKRTSLKEYRLQSRGGKGIIAMKLT-N-TGKLVGCARVCD-DEIMLASTAGKIIRLRVKDIPVQGRATQGVRLFMMA
-GKIVSLAKLA-
>tr|A8DJD0|A8DJD0_9BACT DNA gyrase subunit A OS=Chloracidobacterium thermophilum GN=gyrA PE=3 SV=1
IEDLIPKEEVVITITREGYIKRTPVSAYRTQKRGGVGRRGMTT-AEDEVESLYIASTHSFLLIFTAKGQVYKVRVHEIPDAATSGRGKAIVNLIELPEGE
RIAGTIPVR---SGQFIVFATRRGIIKKTELSEYANIRSNGIVAMGIAEDDELVAVQ-SDGSRHILISTFGGQAICFKE--VRPTGRMAQGIIGIRLR--
-DVTGMSVVG-ED-ILSLSELGLSKRTPITEYPVHHRGGQGVATM--TR--TGGVIKTLPVHEDDEFMVITQQGQVARLKVSDVRQTKRLAQGVKVIALA
-GRVVDACLVE-
>tr|E6W0A6|E6W0A6_DESIS DNA gyrase subunit A OS=Desulfurispirillum indicum (strain ATCC BAA-1389 / S5) GN=gyrA PE=3 SV=1
LEDLIADEPTVITLTNDGYVKRTPADTYKSQHRGGKGKVGLDI-EGDFVTDIFVCSTHEYLMIFTDRGRVYWIKAYNIPEQGRNSRGKAIVNFVDLEK-E
KISTVFPVRD----KFLLFITKNGIAKKTPLSEYAN-RKKGVNAINLDDDDELIQVM-TNG-NSVMVTTRFGASIHFEE--VRAVGRVSRGVKGITLV--
DYVVSAETISKPSYILTVTDLGYGKRTITDEYRLQSRGGKGNLTIKTT-T-NGLVVRGLQVVG-DEILLLSKEGKIIRLDSKHIRITGRNTQGVKLVDLS
-DRIISVAVAK-
>tr|D5MLW1|D5MLW1_9BACT DNA gyrase subunit A OS=Candidatus Methylomirabilis oxyfera GN=gyrA PE=3 SV=1
LEDMLADEEMVIPITHGGYIKRSNLNAYRSQRRGGKGMTGMAT-EEDYVEHLFVATTHSHLLLFTNQGKVHWLKVYGLPQLGHAAKGKALANFLQLGV-E
QITTVIPIRD----RYLLMATRRGIVKKTELNAYGN-RAGGIIAITLDGGDELIAVR-TKG-DEILLGTRQGMAIRFKE--VRSAGRAARGVKGISLE--
DEVVGAEVVA-GAAVLTVTERGYGKRTDPEEYRLQSRGGKGIINIRAT-D-NGPAVGVMLVQG-DQIMMISQEGRITRMRVDEISLIGRATQGVRLQGLE
-TRVAAVTRLV-
>tr|G0JR04|G0JR04_9GAMM DNA gyrase subunit A OS=Acidithiobacillus ferrivorans SS3 GN=gyrA PE=3 SV=1
TEDLITEEEMVVTFTHAGYIKAQPVTVFNAQRRGGKGMATT-TKEEDFVERMFCASTHAYCLFFSNLGKVFWQKVYQLPQAGRGAKGKPIVNMLSLA-TE
RITAVLPVRDFTEGQFVCMVTSHGVVKKTPVMEYSRPRSQGINAINLDPGDRLVAVGLSDGQREFMLFTRHGMAVRFPEAKARAMGRNARGVRGISLEE-
-DVISAQWVDSSQVILTTTANGYGKLTEVDEYRRTNRGGKGVIAIQTNA-RNGDVVGALAVTERDELMLVSDHGTLIRIAINSIRRTGRNAQGVRLINLG
EGQLAGLALIA-
>tr|R7F1K6|R7F1K6_9BACI DNA topoisomerase 4 subunit A OS=Bacillus sp. CAG:988 GN=parC PE=3 SV=1
MTAMIPKEDVITLVTKDGYVKRVSMKSYQASS--T---------GD-YPLGI-FENTLDTLLLFTNKGNYLQVPVHTLPD-----LGKHISNLIKM-ELE
E--AALPVH--AD-CDITIATKDGMIKRTKLKEFK----KPITCMKLK-D-EVIT---T--APDLFLATHNGYGL------V--VGLKAAGVKSMTLK--
-EVSVQNFAPNQEQVIVITTSGTAKRVRLP------RARRGLLLL----RVPYHL-TTYIVS--L--IGL-KGTDISYIKP-EIPI---YSTGSSIYRGN
M--FIK----A-
>tr|R5NAE8|R5NAE8_9FIRM DNA topoisomerase 4 subunit A OS=Firmicutes bacterium CAG:884 GN=parC PE=3 SV=1
ATDMIAKEDVIVVITHDGYIKRVSSRSYSASD--N---------GD-YVIML-ANNTLDVLLLFTDKGNYLYLPVYEVPD-----LGKHISNVIKI-DEE
H--NAYPIY--E--TNVTTFTKLGMVKRSVLKDYK----KKVSAIKLK-D-EVVN---N--GTEVFISTKSGNGL------I--SGVKSSGVKAINLK--
-EVSAYTFDR-EEYLTVITDKSTGKRVKLT------RGKKGVLII----RVPYHL-KTFIVN--I--GYK-VKNDIDYIKQ-ELPI---YSSGTSITKGK
I--FTE----A-
>tr|R7KC71|R7KC71_9CLOT DNA topoisomerase 4 subunit A OS=Clostridium sp. CAG:451 GN=parC PE=3 SV=1
TTALIPKEDTIVTISREGYIKRTSIRSYSASD--I---------ND-YLLGE-FKKTTDTLLVFTSFGNYLYIPVHTIND-----LGKHVSNLVPL-QDE
E--TAIPVS--DK-KNIILATSQGMIKSTSLADFK----KATSCMKLK-D-KLIA---T--KEEIFIETSKGYGL------I--VGIKAGGVKAITLK--
-STSILNFNESNKYLAIVTDKGTGKRMHLK------RARRGLLTI----RVPYHV-AAFFLS--E--IGL-KNGEITYYKG-DLTI---YSTGSTLRKGG
D--FKV----V-
>tr|R5T8G4|R5T8G4_9CLOT DNA topoisomerase 4 subunit A OS=Clostridium sp. CAG:710 GN=parC PE=3 SV=1
TTVMIPKEDVIVMLTKDGYIKRTSLRSYSS-S--T---------ND-YVLGL-FENTLDTLLVFTSLGNFLYLPVHEIPV-----LGKHISNIIKL-DDE
Q--SVVPVK--ED-IDITISTKNGMVKRTKLSDFK----KPINCMKLK-D-EVID---K--YNNIFVSTNKSYGL------I--VGLRTSGVKSINLK--
-FVGVSNFDAYDEYITVITDKGTAKRIKIT------RAKRGLLIL----RVPYRV-KTLITG--Y--VGI-KTSDIKMFKN-EFPI---YSTGSTIVKEQ
L--FKA----V-
>tr|R7M613|R7M613_9CLOT DNA topoisomerase 4 subunit A OS=Clostridium sp. CAG:914 GN=parC PE=3 SV=1
TQEMIPKEDVIVVVTKEGYVKRVSLRGFQANS--D---------ND-YVIGI-YNNTTDTILIFTDMGNYLYLPVYEIPE-----LGKHVSNIISM-EKE
Q--ASIPVY----DKYITSFTEQGMVKRTKLSDFK----KEVSMISLK-DKL-I----S--YSDVFVATRDGYGL------V--VGIRASGVKSIKLK--
-IVVSSLLFDP--FISVIMDRGTAKRLRLS------RANRGILLM----KIPSKV-SIYIEK----INI-TSIKENKTIKL-EISI---ASNGSFIVKDR
L--YPVVKLIS-
>tr|K1SCL3|K1SCL3_9ZZZZ DNA topoisomerase IV subunit A OS=human gut metagenome GN=OBE_17128 PE=3 SV=1
QTEMIPKEDVIVMITKDGYIKRTSYRSYSATN--D---------ND-YIIGQ-FENTLDTLLVFTSFGNYLHIPVYAIYD-----MGKHISNIIPT-GNE
E--KAIPIY--QD-QNIILASKDGMIKRTAIKDFH----KPTSCMKLK-D-KLIA---E--KERVFITTKNGFGL------I--SGVKAAGVKAITLK--
-EVSVSNFSNEDEFLIVLTDHNTGKRIRLS------RTRKGLLVI----RIPYKI-RSFITD--H--LGL-KGSNITEIKV-ELPI---YSTGKEIIKNN
D--FIY----T-
>tr|R6CXK6|R6CXK6_9CLOT DNA topoisomerase 4 subunit A OS=Clostridium sp. CAG:594 GN=parC PE=3 SV=1
MTDMIPKEDVIVVVTSEGYVKRVSKKSYSALN--G---------GD-YVIGL-YENTLDTLLLFTNKGNYLYVPVHTLPE-----LGKHVSNLVPI-KDE
K--KALAVS--DR-EII-TFTSNGMTKKSLLKDFV----KPIMFIKLK-D-EVVD---P--YNEVFIATKKGYGL------I--IGLKTAGVKAINLK--
-NASACIFDG-FEYVTVITHKGLAKRVKLS------RAKRGLLLL----RVPQEL-KTYVSD--M--IMLVSDNDTKEIKL-EIPI---YSIGSTITKKK
D--YEI----I-
>tr|R6Y7N4|R6Y7N4_9CLOT DNA topoisomerase 4 subunit A OS=Clostridium sp. CAG:433 GN=parC PE=3 SV=1
AIDMIQKEDVIVVITKEGYIKRVSSRSYQSSK--N---------ND-YVLGL-YENTLDTVLLFTNLGNYLYVPVHEIPD-----LGKHISNIRTI-KEE
K--GCIPVT--TN-DIITIFTKNGMIKRTNLSEFK----KAVTCIKLK-D-EVVN---K--NKEVLISTENGYGL------V--SGIKASGVKSINLK--
-IVSGCLFNK-DEYIAVFTNKGTAKRIKLE------RARRGLLLI----RVPYKV-KTFVIN--K--LGFMTSSDIDYIRS-EISI---YSTGSSISKKK
L--FEI----K-
>tr|R5MEJ7|R5MEJ7_9MOLU DNA topoisomerase 4 subunit A OS=Mycoplasma sp. CAG:956 GN=parC PE=3 SV=1
TTDLITKENVMVALSNEGYIKRVSMKSYTSSN--G---------GD-YLKYL-FESTLDNLVIFTNLGQYLYVPVHTIFE-----LGKHINNLVTG-SSE
Y--GAFILK--K--EKITFVTKNGLVKQSILKDFV----KAMLAFKLK-D-EVIA---S--KPRTVLISEAGYYV------I--VGARASGVRGMNLK--
-V-AAGLSLDSSEYLSIFTNNKTAKRVKVS------RAKKGSTLI----KVDYKI-KALLTD--E--LFLKCDNEITKIKN-DISI---KSTGGTISRYK
D--FTS----T-
>tr|R5LL57|R5LL57_9MOLU DNA topoisomerase 4 subunit A OS=Mycoplasma sp. CAG:877 GN=parC PE=3 SV=1
TTAMIPKEDVVVLVTKDGYIKRTSFRSYTASN--P---------ND-YIIGL-YENTTDTLLVFTTAGNYLHIPVHIIPD-----MPKHVSNLIEM-TGE
S--AAIPAY--TE-KNIVIATHDGMIKRSKLKDFK----KETSCMKLK-D-YVIA---D--KPCLFLTTDTGYGL------V--VGVKASGVKAIKLK--
-NVSINQYSQTDEFISIITTKGTGKRVRLN------RTRRGLLVI----RVPYKL-KTFITD--Y--IGL-KNSDINIIKL-ELPI---HSIGSQLTKHN
T--FQE----S-
>tr|F2IA69|F2IA69_FLUTR DNA gyrase subunit A OS=Fluviicola taffensis (strain DSM 16823 / RW262 / RW262) GN=gyrA PE=3 SV=1
IEDLIPDEEVVITISHAGYIKRTNLDEFKVQSRGGMGSKGSTT-DKDFLEHLFVATNHNYLLIFTEKGRCFWMRVFEVPEGNKTAKGRAIQNLLNIEQDD
KIKAYVKVKT--QNNFIVMCTKEGIIKKTSLEAYSR-RANGINAITIRENDELLEARLTDGTNEMVLATKAGRAIRFN---VRPMGRNASGVRAVTLQDT
-DVVGMICVKDTETIMVVSEKGYGKRSFLNVYRITNRGGKGVKTINITD-KTGPLLAIKTVA-EDDLMIITKAGVTIRMHIDGIRVMGRAAQGVRLINLK
-TAIAAVARVP-
>tr|A0A0P7BYK1|A0A0P7BYK1_9BACT DNA gyrase subunit A OS=Leadbetterella sp. JN14-9 GN=AFM12_02970 PE=4 SV=1
IEDMIPDDEMLVTVSNEGYIKRTALVEYRTQNRGGVGSRGVKT-DTDYTEHLFSATNHNYLLFFTEKGKLFWLRVFEVPEGNKTSKGRAIQNLINIESDD
SIRAVLNVKT--NNNFIIMCTKNGVVKKTLLEAYSR-RVNGIIAININEGDQLLDVALTNGDNHIIIAASEGKAVRFH---IRAMGRGATGVRGIKLS--
-DAIGMVCVNRDAQLMVVSENGYGKRSDIEEYRITSRGAKGVKALNITD-KTGKLVAIKEVT-EDDLMIITIKGILIRMSVSDLRVMGRATQGVRLIKLN
-NGIASVTRIV-
>tr|A0A0C1RB75|A0A0C1RB75_9CYAN DNA gyrase subunit A OS=Tolypothrix bouteillei VB521301 GN=gyrA PE=3 SV=1
DRDLIANEKVVILVTEQGYIKRMPVNTFEAQSRATRGKAAAKM-EDDGVEHFLTCCDHDSVLFFSERGVVYCLKTYQIPVSSRTSRGTPIVQLLPVPKEE
KITSIVPVT---SDEYLVMLTNGGYIKKTELAAFSNIRANGLIAISLEEGDQLRWVRRARVEDSVIIGSRRGMAIHFRC--LRPLGRATRGVKAMKLR--
-DLVGMDILPAGPWVLVITMGGYGKRVPVSQFRLQKRAGQGIMATKFRKI-KDQLATLHIVNDDAEIMMVTSRGIIIRQAVNAISIQSRSATGVRVQRLD
-DVITGVAIVP-
>tr|A0A0C1TDK5|A0A0C1TDK5_9CYAN DNA gyrase subunit A OS=Scytonema millei VB511283 GN=gyrA PE=3 SV=1
AIDLIANEKAVILLTEQGYIKRMPLDTFEAQSRATRGKSGTRM-EDDGVDHFLTCCDHDSVLFFSDRGVVYSLKAYQIPVGSRTSRGVPIVQMLPIPKEE
RITSIVPVS---SDEYLVMLTKGGYIKKTELAAFTNIRANGLIAISLEEGDQLRWVRRARVEDSIIIGSRFGMAIHFRT--LRPLGRATRGVKAMKLK--
-DLIGMDIIASGPWVLIVTMAGYGKRVPVSQFKLYNRATKGKIATKFNRKFKDKLAALMVVN-GDELMLITTRGIIIRQSTDAIPRQSRSATGVRVQRLD
-DAIAAVALVP-
>tr|K9XAV0|K9XAV0_9CHRO DNA gyrase subunit A OS=Gloeocapsa sp. PCC 7428 GN=gyrA PE=3 SV=1
DTDLIANEKALILVTEQGYIKRMPIDAFEAQSRATRGKAATRM-EDDGIEHFLTCCDHDSVLFFSDRGVVYCLKAYQIPLGSRTSRGTPMVQMLPIPKDE
KITSVVPVS---SDEYLVMLTRGGYIKKTELSAFSNIRANGLIAISLEEGDQLRWVRRARVEDSIIIGSRYGMAIHFRT--LRPLGRATRGVRAMKLR--
-DLIGMDILPSGPWVLIVTMGGYGKRVPVTQFKLYNRATKGKIATKFRKGFKDQLAALHIVN-NDELMIVTSRGIIIRQAVKAISPQSRSATGVRVQRLD
-DAIAAVALVP-
>tr|K9B0Y3|K9B0Y3_9MICO DNA gyrase subunit A OS=Brevibacterium casei S18 GN=gyrA PE=3 SV=1
MEDLIPEEEVVVTITRGGYAKRTQSTLYRAQHRGGKGIKGA-QRGDDVVEQFFVTSTHNWLLFFTNTGRVYRAKAYEIPEGSRDAKGQHVANLLALQPGE
TIAKVLSIR---AE-FLILATKSGVVKKTRLSEYDS-RTGGVIAINLREPDELVSAR--SSEDHLLLISRKGMSIRFAD--IRPLGRVTGGVTGMKFK-D
-DLLTMDVVQPGTYVFVVTEGGYAKRTPVDEYRVQGRGGLGIRVAKIT-E-RGDLVGGLIVDG-EEVLVVMERGKVVRSNIDEVPA-GRNTMGVVFAKPG
-NRIIAVTRGP-
>tr|R5VZQ2|R5VZQ2_9FIRM DNA gyrase subunit A OS=Firmicutes bacterium CAG:631 GN=gyrA PE=3 SV=1
DEDLITKEDIIVTLTLNGYIKRVPMDTFKTQNRGGKGIKGMAT-EEDVVDKIVIANTHKDIIFFTNFGKVYRLRGHQIPEG-RTAKGIPVINLL-NDANE
KVRSIISLN-Y--NHTLVFVTKNGIVKRVALKEFESIRQKGKIAIHLKEDDELIDVKLTDGTAQILIASSNGKVVRFN---VRVMGRSASGVKGINVN--
-EVIGVATSLEGEYLLVISKNGYGKMSLITDYR-TKRGSQGVLTMKISE-KNGLLSNIKAVN-TEDLLVVTNQGIVIRTSLEQVK-AGRNTLGVRIIKLN
-GEVSSIAIAA-
>tr|A0A088T034|A0A088T034_9MOLU DNA gyrase subunit A OS=Mollicutes bacterium HR1 GN=gyrA PE=3 SV=1
DEDLIPVEDVIITITSSGYCKRMNTEVYKTQNRGGKGMKGIKT-EDDVVEHLINTSTHDFILFFTTKGRVYKMKGYKVPNG-RTSKGLPIVNLLNLDD-E
DLAAVAKIS--S-EDFLFFVTKRGVVKRTPVTDFKN-RTTGIKAINLREEDELLAVR-TDG-RDVIIGASNGKAIRFHE--ARAMGRVASGVRGILLG--
-AVVGFTIVTERTQILVVTENGYGKRTQVDEYRQQNRGGKGVKTLNIT-E-NGQLTKLRSV-G-EDLIITTTKGMIIRLPIEQIATSKRATQGVRLIKLN
GH-VATIAIVP-
>tr|U5S9P5|U5S9P5_9LACT DNA gyrase subunit A OS=Carnobacterium sp. WN1359 GN=gyrA PE=3 SV=1
DEDLIEEEDVVITLTNKGYIKRLPSSEFKSQRRGGRGIQGMGV-DDDFIETLVSCSTHDTLLFFTNNGKVYRSKGYEIPEYGRTAKGIPVINLLGI-DGE
TVQAVINVR--EEGLYLFFTTRLGTVKRTSVKAFSN-RSNGLKAIVLKEDDELMSVS-TDG-QNIIIGTHLGYAVSFHE--VRNMGRTASGVRGIRLR--
-DVIGVDLLTEDSEVLIITEKGYGKRTKASEYAIKGRGGKGIKTANIT-S-NGSLAGLTTVKE-EDIMLITNTGVIIRFNVSAVSQTGRATLGVRVIRVA
D-KVSTMAKVE-
>tr|M0M3Y7|M0M3Y7_HALMO DNA gyrase subunit A OS=Halococcus morrhuae DSM 1307 GN=gyrA PE=3 SV=1
HEDLIPDEEVVVVMTENDYIKRMPAGQFDPQGRGGKGIIGTKL-DGDRVSAVFRANTHDYLLTFTNQGYVYRLKVYEVPEMGRTARGKSAINLV-DDDGE
AITAVVATD--D-EECLTMVTRDGYVKRTCASEFENIHSGGLIATRLEDGDELVDVA-TDDDGDLLIGTQRGMAIRFPK--AREMGRSARGVNGVDLQ--
-DVAGVVTATDDADLLTVTENGYGKRTPMSEYSTQSRYGKGLKDI--NR--NGRVTAIESATADDDLVAMSDTGQIMRTPVGDISTVGRNTMGVTIMALE
-GGIACIDVLE-
>tr|V4XTA8|V4XTA8_9ARCH DNA gyrase subunit A OS=uncultured archaeon A07HR67 GN=gyrA PE=3 SV=1
HEDLIPEEECLVVMSEDDYIKRMPLETFRTQNRGGKGIIGMDL-ESDRVSSVFAANSHDYLLVFTNHGQIYRLKTYEIPELSRTARGKSAVNLLDLDDGE
EIEAVVN---F-GEEFLTMVTRDGYIKRTAVDEFENIRSTGIRAIRLDDDDELADVE-TDGEAHIVIGSRDGMAIRFEE--VRPMGRTARGVIGIDLR--
-DVAGVAAVDIHDWVLTVTQNGYGKRSDLAEYRPQSRNGMGLVDI--GR--NGETVAIEAVSYGDHLVAMSADGQIVRTRVEEVSTVSRNTMGVIVMDLD
-DEVASVDIVP-
>tr|U1QK87|U1QK87_9EURY DNA gyrase subunit A OS=Halonotius sp. J07HN4 GN=gyrA PE=3 SV=1
HEDLIPEEDIVVAMSEDDYIKRMPLSTFSAQNRGGKGIIGTGL-EGDAVSSVFVANTHDYLLCFTTHGQIYKLRGFQIPEMSRTARGKSAVNILDLDDGE
ELTAVVNTD---ADRYLTMVTGNGYIKRTAVDAFQNIHRSGIRAIRLEDDDELVDVEVTDGDRTLVMTTADGMSIRFDE--VRAMGRSARGVCGIDLQ--
-TVAGVAAVDAHSWVLTVTKNGYGKRSDIDEYRVQSRNGKGLIDI--GD-RNGPVCGMETVGPGDHLLVMSQSGQIMRTPITDVSAVGRNTMGVIVMDLD
-TRVSCLDVIP-
>tr|V4Y8B4|V4Y8B4_9ARCH DNA gyrase subunit A OS=uncultured archaeon A07HN63 GN=gyrA PE=3 SV=1
HEDLIPEEDVVVAMSEDDYIKRMPLSTFSAQQRGGKGIIGTDL-EGDAVSSVFVANTHDYLLCFTNHGQIYKLRGFQIPEMSRTARGKSAVNLLDLDDGE
ELTAVVNTD---ADRYLTMVTRDGYIKRTGVDEFQNIHKSGIRAIRLEDGDALVDVEVTDGDRSLVVTTTGGMSIRFAE--VRAMGRSARGVRGIDLQ--
-TVAGVAAVDTHSWVLTVTGNGYGKRSDIDDYRVQSRNGKGLIDI--DD-RNGSVCAMETVGPGDHLVVMSKSGQIMRTPVQDISTVGRNTKGVIVMDLD
-DSVACLDVIP-
>tr|A5HXQ3|A5HXQ3_CLOBH DNA gyrase subunit A OS=Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A) GN=gyrA PE=3 SV=1
IEDLIEDKKVIITLTHGGYIKRLDMDTYSSQKRGGKGIQATST-QDDFIENMFVTSTHSTILFFTNRGKVYKLKAYEIPEG-RTAKGTNIVNIIPIEN-E
KIQTVIGLK---DMKHFVMCTRNGIIKKTEIKKYSS-RKGGLNAINLREDDELIDVK-TKG-NEIIIVTQNGYCIRFNE--VRPMGRVATGVKGITLR--
-DAVSMEVVLE-EALLSISENGFGKRTDIEEYPIHRRGGKGVITYKIT-D-TGPIVGARFIKD-DELMLVNSGDVAIRINVSEISKTSRNAMGVKLMRTS
EE-IVAIAKIK-
>tr|N9TTC3|N9TTC3_9MOLU DNA topoisomerase (ATP-hydrolyzing) OS=Mycoplasma bovigenitalium 51080 GN=parC PE=4 SV=1
---LVVDEEAVLTISKHGYIKRFSNRVYESNDWTTFG-------ED-SIIFSNRTRTTNTLLLFTNLGNYALIPVYKINE----AYGNHLSEFVE--G-E
E--SAIEIK--E-NMYVVLLSRQGQGKRVLLKD-FR---KAFNAISL--DDQLVG---N---GDILIVTDFGLAS------M---GTKASGVKSCFLS--
-AVADFAIVN-ENLVALIDENKHIKIVKVE-----SKKHLGKPIF--FT---APN-IKSIN--YSELFVKNTNNETDLIKN---PT-KV---GEGFSKIK
--NIQ-ITFKT-
>tr|L0RVC7|L0RVC7_MYCC1 DNA topoisomerase (ATP-hydrolyzing) OS=Mycoplasma cynos (strain C142) GN=MCYN0852 PE=4 SV=1
---LIKDESTYLGISRNGFIKRFSERTAESNSMSTYA-------DD-NLVYYNKTNTMKTILIFTNLGNYIQLPIYKINE----ANGIKLSDISE--N-E
R--SVIEVS--E-NIFVVLGTKNGYFKKVKLSE-FR---KSYNAINI--DDEVIN---N---KNIVIITRNGLCS------I---SPKAKGNKGIYLS--
-NVAGYTLVD-SDIVNILSSSGKIKQLRAS-----PKNIKGKKVV--KD---FEV---DV---PGIVLATNGNNQTEKISE---TN-EV---NSEIIQLD
--QLL-IQFQK-
>tr|F9UJ28|F9UJ28_9MOLU DNA topoisomerase (ATP-hydrolyzing) OS=Mycoplasma columbinum SF7 GN=MCSF7_00025 PE=4 SV=1
---LIKEENVYLSVTKYGYLKRFSEKIYESNNFLTYG-------ED-KLIYFDKVNTINNVLIFTNFGNYALLPVYKIDE----SNGIHLSEFVE--G-E
E--SVLNVL--Q-LKYVCLFSKQGQGKRVLLKD-FR---KTYTALKL--NDELLD---D---KDVLLITKRGLAS------V---GTKSNGTRSCYMP--
-ILTAFAMVS-DDVVTLLANDEYIKNIKVS-----PKKNLGKKLF--FY---KEI-VKDAE--KSEIFVKNENNEIELVKN---PL-NT---SEGFKKIK
--KPI-ISFKT-
>tr|C4XE59|C4XE59_MYCFP DNA topoisomerase (ATP-hydrolyzing) OS=Mycoplasma fermentans (strain ATCC 19989 / NBRC 14854 / NCTC 10117 / PG18) GN=MBIO_0166 
---LVKEEETYIGVTKHGYLKRMSNKVVNSNDFLTYG-------GD-KIICFEKSNTINNLLLFTNLGNYAMVPIYKIEE----SFGVHLSDFVE--G-E
E--GAINVT--I-QNYVCLFTKEAQGKRVVLKE-FR---KTFTAMKL--GDELVG---N---KDVLLITKRGMAS------V---GTKSNGTKSCYMP--
-MIVAFAMVE-HETLAMLANETYVKRIHVS-----GKKNLGKPIF--LT---KPI-VTDAY--DDYIFVTNDENQVERIVE---PI-SI---NEGFSKIK
--NSA-LSFKK-
>tr|Q6KHI4|Q6KHI4_MYCMO DNA topoisomerase (ATP-hydrolyzing) OS=Mycoplasma mobile (strain ATCC 43663 / 163K / NCTC 11711) GN=parC PE=4 SV=1
---LIQAEETFVGISRDGYIKRFNQKIHDSNEMQTYL-------DD-ALIFLSKTLTTGKLLIFTNQGNYISIPIFKIAE----ELGIHLNDFAT--N-E
F--KVLYVD--K-DFSITLITKKGFGKKVQLPE-FR---KSYPAIKF--GDELLN---N---LDILLVNTKLEVY------F---GIKAAGVKISDNA--
-KISAAIAYS-NDTLVFLTESGHARKINPK-----NQKSIKTFLS--AP---SGI-IKYIF--NVDLAIRTTDSIV---NT----E-SE---TESFTNLH
--GIYAISLGD-
>tr|A0A060Q2E5|A0A060Q2E5_9MOLU DNA topoisomerase (ATP-hydrolyzing) OS=Mycoplasma californicum HAZ160_1 GN=gyrA PE=4 SV=1
---LVADEEVVLSVTKHGYIKRFSERVKDSNDWDTFG-------ED-QIEFYGRVNTTNNILAFTNFGNYAMVPVFKIAE----SYGSHLSEFVE--R-E
E--SVINVK--K-TEFIVLLSKQGNGKRVLLKD-FR---KTFTAIKL--DDVLIS---N---KDILILTERGLAS------M---GTKSNGVKSCFLS--
-GVTAFAMVE-KENIMLVSQGDYVKRLKVS-----SKKHLGKPLF--SN---KLI-VKDIE--NTEIFVRLNTGQLDKLKA---SL-QN---SDSFSRIK
--NIV-LHFKR-
>tr|A0A0F5H1Q7|A0A0F5H1Q7_9MOLU DNA topoisomerase (ATP-hydrolyzing) OS=Mycoplasma meleagridis ATCC 25294 GN=parC PE=4 SV=1
---LVKEEIVYVSVSKNGYLKRFSERVKETNAIDTFA-------GD-FILYFNKLQTTDNLLIFTNLGNYAIIPVYKLSE----TLGSHLSDFVE--N-E
E--SVLKVK--E-KYFVGLFTKYGQGKRVKLKD-FR---KTFTAMKL--NDKLIG---T---QDVLLITKRGLAS------V---GTKSNGTKSCYMP--
-IITAFAFVN-DDIVTLVANNEYIKNIKVS-----PKKNLGKKIF--FY---KEI-VNDCA--DSKLLLVTNDNNLEGINK---PL-SS---NEGFTKIK
--KIK-ASIYL-
>tr|A5IXX2|A5IXX2_MYCAP DNA topoisomerase (ATP-hydrolyzing) OS=Mycoplasma agalactiae (strain PG2) GN=parC PE=4 SV=1
---LVKEEQVFLGISKFGYIKKVSKKIYESNLINTYG-------DD-NILFYDNASSLDKLLLFTNFGNYAYLPVFKVHE----SFGTHLSDFVD--G-E
E--SAIKVS--S-SNYVCLFTKKGQGKKVLLKE-FR---KTFVAMKL--DDELIG---N---KDVLLITKNNFAS------V---GLKSNGNKACYLA--
-YLSAFAVVS-NDSVVLINANNRAKVVNVS-----SKANKGVALF--ST---NS--IKQCD--SSKILIVNNQGQAEKIQD---AK-AY----AKFINFD
--DLR-VSLIS-
>tr|E4Q0I9|E4Q0I9_MYCBG DNA topoisomerase (ATP-hydrolyzing) OS=Mycoplasma bovis (strain ATCC 25523 / PG45) GN=parC PE=4 SV=1
---LVKDEEVFLGISKFGYIKKVSKKTYESNLITTYG-------DD-NILFYDLASSLDKLLLFTNLGNYAYLPVFKVNE----SFGIHLSDFVD--G-E
E--SVIKVS--V-TNYVCMFTKKGQGKKVLLKD-FR---KTFMAMKL--DDELIS---N---KDVLLITKNNFAS------V---GLKSNGNKACYLA--
-GLVSFTVVK-NDSVALVSQSNKIRLINVS-----SKQNKGVPIF--GL---NN--IVQCD--ETKLLLVNNQGQAEKIQN---FK-AS----TKFINFD
--DIR-ISLIS-
>tr|G8R2P3|G8R2P3_OWEHD DNA gyrase subunit A OS=Owenweeksia hongkongensis (strain DSM 17368 / JCM 12287 / NRRL B-23963) GN=gyrA PE=3 SV=1
IEDMIPNEEVVITISHAGYIKRTPLTEYKKQNRGGVGQKGVNT-DADFVEHIFVATNHQYMLFFTEWGRCYWLRVYEIPEGSKASKGRAIQNLINIPQDD
KVRAFINTKK--NSHFIVMVTEKGVIKKTPLEAYSR-RVNGINAITVREGDLLLEAKLTTGKDEILMAKKSGKAIRFN---VRSMGRNASGVRGVTLEE-
-DVIGMVTVPHEPTILVVTEKGYGKRTLLE-YRVTNRGGKGVKTLNTTE-KTGNLVAIKAVS-EEDLVIINKSGVMIRTGVAELRVMGRATQGVRIINLK
-KAIASVAKVP-
>tr|C2GFG7|C2GFG7_9CORY DNA gyrase subunit A OS=Corynebacterium glucuronolyticum ATCC 51866 GN=gyrA PE=3 SV=1
DEDLIAQENVVVTITSGGYAKRTKVDAYRSQKRGGKGVRGA-EKMDDVVRHFFVCSTHDWILFFTNFGRVYRLKAYEIPEASRTARGQHVANLLEFQPGE
TIAQVIQIQ---EP-YLVLATRKGRVKKSRLTDYES-RSAGLIAINLNE-DSLIGAV--SGEDDLLLVSQRGQAMRFSD--LRPMGRATAGVKGMRFK-D
-DLLSMCVTS-GDYLLVATEGGYGKRTAMEEYPAKGRGGLGVTTLKYQ-PKRGKLIGALAVNG-DEIMAITSAGGVIRTEVSQIRP-SRSTMGVRLVNLP
-GSLYAIDRNV-
>tr|L9V9C9|L9V9C9_NATMM DNA gyrase subunit A OS=Natrialba magadii (strain ATCC 43099 / DSM 3394 / NCIMB 2190 / MS3) GN=gyrA PE=3 SV=1
HEDLIPEEEVFVVMTEDDYVKRMPISQFDPQGRGGKGIIGADV-EDDRVATVFRANTHDYLLCFTNQGKVYQLKTYEIPEMGRTARGKSAVNIL-DDPGE
DITAIVDTD--D-DEFVTMATRHGYVKRTAGSEFDNIRSTGIIAADLQEGDELVDVE-TDGTKDLVIASENGMTIRFDE--VRAMGRNARGVNGIDLQ--
-DVAGLVATDEEQDLLTVTQNGYGKRTPLSEYRTQSRYGKGLIDI--GR--NGPVTTAKAVSADDQLVMMSERGQIVRTRVDEISTVGRNTMGVIVMDVD
-GAVASVDVVP-
>tr|D8J640|D8J640_HALJB DNA gyrase subunit A OS=Halalkalicoccus jeotgali (strain DSM 18796 / CECT 7217 / JCM 14584 / KCTC 4019 / B3) GN=gyrA PE=3 SV=1
HEDLIPEEDSLILVTEDDYVKRMPVSAFDPQGRGGKGIIGANL-EGDRVSKVFRANTHDYLLCFTNHGKAYQIRGFDVPEMSRTARGKSAVNIL-DDPDE
ELTAVVNTD--D-EEFLTMVTENGYVKRTEASAFERVRSSGLIAASLEEGDRLVDVT-TDGSADLLIATRNGMAIRFPE--ARAMGRTARGVNGIKLQ--
-DVVGLVTADESRSLLTITENGYGKRTPFSEYRTQSRYGKGLIDI--GR--NGPVAAVESVSEDDDLVVMSDDAQIMRIHAADVSRVGRNTKGVIVMRLA
-DRVASVDVIP-
>tr|C7NP30|C7NP30_HALUD DNA gyrase subunit A OS=Halorhabdus utahensis (strain DSM 12940 / JCM 11049 / AX-2) GN=gyrA PE=3 SV=1
REDLIPEEECLVVVTEDDYIKRMPADRFDAQHRGGKGIIGADP-EGDRVSTVFRANTHDYLLAFTNHGQVYRLRTYEIPEMSRTARGKSAVNLI-NDDGE
EITAVVSMD--D-DECITMATRQGYVKRTCCSEFENILSTGIIAAKLEDGDELVDAV-TDGESDLVIATEDGMTIRFDE--ARQMGRTARGVRGIDLR--
-DVAGVVATDEERALLTVTERGYGKRTPLSEYRTQSRYGKGLIDI--GR--NGGVTAVNAVAEDDHVIVMSATGQIMRCPVEDVSTVGRNTMGVTIMDVA
-DTVASVDVIP-
>tr|L9W2S5|L9W2S5_9EURY DNA gyrase subunit A OS=Natronorubrum bangense JCM 10635 GN=gyrA PE=3 SV=1
HEDLIPEEEVFVVMTEDDYVKRMPIDQFSPQGRGGKGIIGADV-DGDRVTTVFRANTHDYLLCFTNQGKVYQLKTYEIPEMGRTARGKSAVNIL-DDTDE
DITAIVDTD--D-GEFVTMATRNGYVKRTAGSEFDNIRSTGIIAADLEDGDELVDVE-TDGSQDLVIATEGGMTIRFDE--VRSMGRNARGVNGIKLE--
-DVAGLVATDEERALLTVTQNGYGKRTRLSAYRTQSRYGKGLIDI--GR--NGPVTAVKAVADDDELVMMSERGQIVRTRVDDISTVGRNTMGVIVMDVE
-GAVASVDEIP-
>tr|M0BST6|M0BST6_9EURY DNA gyrase subunit A OS=Halovivax asiaticus JCM 14624 GN=gyrA PE=3 SV=1
HEDLIPEEEVLVVMTEDDYVKRMPVSNFDPQGRGGKGIIGCDV-EDDRVTTVFQANTHDYLLCFTNQGQVYQLKAYEIPEMGRTARGKSAVNIL-DDPGE
ELTAIVDTD--D-DEFVTMVTRHGYVKRTRGDEFDNILTTGIIAASLEDGDELVDVE-TDGTNDLVIGTEQGMTIRFDE--ARAMGRNARGVNGIKLE--
-DVAGLVATTEERALLTVTENGYGKRTLLSEYRTQSRYGKGLIDI--ER--NGPATALKAVAPDDQLVIMSERGQIMRTRASEISTVSRNTMGVTVMDVE
-GAVASVDVLS-
>tr|L9WXW4|L9WXW4_9EURY DNA gyrase subunit A OS=Natronococcus amylolyticus DSM 10524 GN=gyrA PE=3 SV=1
HEDLIPEEEVVVVMTEDDYVKRMPIDDFDPQGRGGKGIIGADV-DDDRVSTVFRANTHDFLLCFTNQGKVYQLKTYEIPEMGRTARGKSAVNIL-DDAGE
DITAIVDTD--D-DEYVTMVTRNGYVKRTAGEEFDNIRSTGIIAADLEEDDELVDVE-TDGSQDLVIATEGGMTIRFDE--VRAMGRNARGVNGIKLT--
-DVAGLVATDEERALLTVTRNGYGKRTPLSEYRTQSRYGKGLIDI--DR--NGHVTTVKAVDADDHLVMMSERGQIVRTRVDEVSTVGRNTMGVTVMDVD
-GAVASVDVLP-
>tr|L0AC50|L0AC50_NATGS DNA gyrase subunit A OS=Natronobacterium gregoryi (strain ATCC 43098 / CCM 3738 / NCIMB 2189 / SP2) GN=gyrA PE=3 SV=1
HEDLIPEEEVVVVMTEDDYVKRMPIETFDPQGRGGKGIIGADV-DEDRVATVFRANTHDYLLCFTNQGNVYQLKTYEIPEMGRTARGKSAVNIL-DDDGE
DITAIVDTD--G-DEFVTMATRNGYVKRTASEEFDNIRSTGIIAADLEEGDELVDVE-TDGSQDLVIATEGGMTIRFAE--VRAMGRTARGVNGIKLQ--
-DVAGLVAANGGQALLTVTRNGYGKRTPIEEYSTQSRYGKGLIDI--ER--NGPVTAIKAVSEDDHLVLMSEDGQIVRTRVDEVSTVGRNTMGVIVMQVE
-DAVASVDEIP-
>tr|W0JRU3|W0JRU3_9EURY DNA gyrase subunit A OS=Halostagnicola larsenii XH-48 GN=gyrA PE=3 SV=1
HEDLIPEEDVVVVMTEDDYVKRMPIDAFDPQGRGGKGIIGADV-EGDRVSAVFQANTHDYLLCFTNHGQVYQLKTYEIPEMGRTARGKSAVNIL-DDDGE
EITAVVDTD--D-DECVTMVTKNGYVKRTAGEEFDNILTTGIIAASLEESDELVDVE-TDGTTDLVIATERGMTIRFDE--VREMGRNARGVNGIKLQ--
-DVAGLVAMDQDRSLLTVTQNGYGKRTLLSEYSKQSRYGKGLIDI--NR--NGPVTAVKAVTEDDHLVAMSERGQIMRTRAGEISTVGRNTMGVTIMDVE
-DAVASVDVIP-
>tr|A0A0R2LH47|A0A0R2LH47_9LACO DNA gyrase subunit A OS=Lactobacillus pobuzihii GN=IV66_GL001935 PE=4 SV=1
DEDLIEEESVIVTLTHNGYIKRMPTSEFKSQNRGGRGVQGMGV-EGDFIEQLISTSTHDELLFFTNTGKVYSSKGYQIPEYGRSAKGIPVINMLNI-AEE
KIATVITVPE-TDDKFLFFTTKNGVVKRTAVSEFLN-RKNGLKAITLREGDELIGVA-TDG-QNMIIGTHGGYAVSFSE--VRSMGRSAAGVRGIRLD--
-NVIGADILGPNSNVFVISEQGYGKQTPASEYAIRGRGGKGVKTVNVT-A-NGPLVGLTTVFD-EDIMVITNKGVLIRFDVANVSTTGRSTLGVHLINLE
G-FVSTMAKVA-
>tr|A0A0R1ZDK5|A0A0R1ZDK5_9LACO Dna gyrase subunit a OS=Lactobacillus aviarius subsp. araffinosus DSM 20653 GN=FC64_GL000181 PE=4 SV=1
DEDLIEEESVAITLTHNGYIKRLPTSDFKAQRRGGRGVQGMGV-DDDFIEHLVTTSTHDRLLFFTNLGKVYSMKGYEIPEYGRSAKGIPVINLLNI-DGE
KIATVINIP--EHAKYLFFTTKEGTVKRTPVEDFEN-RKNGLKAINLHDGDELINVS-TDG-QNMIIGTHLGYAVSFNE--VRSMGRSAAGVRGIRLR--
-NVIGSDILVPGSDVFVISEKGYGKRTPVSEYPIKGRGGKGIKTSNIT-E-NGPLAGLTIVND-EDIMVITNKGVLIRFNVADVSQTGRSTLGVHLINLE
D-TVSTVAKVD-
>tr|U2HUM2|U2HUM2_9SPHI DNA gyrase subunit A OS=Sphingobacterium paucimobilis HER1398 GN=gyrA PE=3 SV=1
MEDFIDDEEIVITISHNSYVKRTPLSEYKRQGRGGKGAIGSNT-DEDFTEHIITATAHNYMLLFTEAGRCFWLRAFEIPEGSRTSRGRALQNIINIPKDE
KIKAYILVKK--ENNFIIMCTKQGTIKKTSLEAYSR-RANGINAININEGDQLIEACLTSGSSEIVMALRSGRAIRFN---VRPMGRTATGVRGITLDT-
-DVVGMISVDNELSVLVVSEKGYGKRTDIEDYRITNRGGKGVKTINVTE-KTGELVAIKGVT-NDDLMIINKSGIVIRIGVDSLRVMGRATQGVRLITLK
-TEIASITKVA-
>tr|A0A0B8T6G8|A0A0B8T6G8_9SPHI DNA gyrase subunit A OS=Sphingobacterium sp. ACCC 05744 GN=gyrA PE=3 SV=1
MEDFIDDEEIVITISHNSYVKRTPLTEYRRQGRGGKGAIGSST-EEDFTEHIITASAHNYLLLFTDKGHCFWLRAFEIPEGSRTSRGRALQNIINVPKEE
KIKAFIKIIK--ENNFIIMCTKKGTIKKTSLEAYSR-RANGINAININEGDELLEACLTTGGSEIVMALRSGRAIRFN---VRPMGRTATGVRGITLAE-
-DVVGMIAVDSDTTVLVVSEKGYGKRTDVEDYRVTNRGGKGVKTINVTD-KTGELVAIKGVT-ADDLMMINKSGIVIRIGVETLRVMGRATQGVRLITLK
-TAIASITKVA-
>tr|Q7VRW9|Q7VRW9_BLOFL DNA gyrase subunit A OS=Blochmannia floridanus GN=gyrA PE=3 SV=1
LENLINQRDVVVTLSYQGYVKYQPLTDYEAQKRGGKGLTTR-IKEEDFITQLLIANTHDTVLLFSNYGRIYWMKVYRLPKANKGSRGRPIINLLPLD-NE
RITVILPVQNYTTGHQVFMATSSGFVKKTALMEFSRPRNVGIIALNLNNGDELIGADITNGDNEVMLFTAYGKVVRFQETQVRSMGRSASGVRGVHLL--
QGVVSLIIPKD-SSILTVTENGFGKRTNQSEYPLKSRAIQGVISIKVTE-RNGNVVGAVQVDQGDQIMIVTDSGRLVRIRVSEVNIIKRNTQGVMLIRTA
CDHVVGLQRVV-
>tr|L0MX04|L0MX04_9ENTR DNA gyrase subunit A OS=Candidatus Blochmannia chromaiodes str. 640 GN=gyrA PE=3 SV=1
VENLINQKDVVVTLSYQGYVKYQPLTDYEAQKRGGKGLATR-IKEEDFITRLLIANTHDTVLLFSNYGRIYWMKVYRLPAASRGSRGKPIINLLPLD-NE
RITAILPIQNYTTGHQVFMATSSGVVKKTPLTEFSRPRNVGIIALNLNDGDELIGADVTDGSNEVMLFTAYGKVVRFKETQVRSVGRSAIGVKGIHLL--
QGVVSLIIPKD-SSILTVTRNGFGKRTNQSEYPIKSRATQGVISIKVTE-RNGHVIGAVQVNQSDQIVMITDLGRLVRTRVSEVNIIRRNTQGVMLIRTA
CDCVVGLQCVV-
>tr|A0A0E3Y7G8|A0A0E3Y7G8_9ENTR DNA gyrase subunit A OS=Blochmannia endosymbiont of Polyrhachis (Hedomyrma) turneri GN=gyrA PE=3 SV=1
VEDLIDREDVVVTLSYQGYVKYQPLADYEAQRRGGKGLITR-VKEEDFITRLLVTNTHDTILLFSNYGRIYWMKVYRLPAAKHISRGRPIVNLLPLE-RE
RITAILPIRKYEIGCQVFMATSSGLVKKTSLTEFCRPRNMGIIALNLNKGDELIGADITYGDNEVMLFSKYGKVVRFQENQVRSVGRTAIGVRGMNLL--
NGVVSLIIPRG-SSILTVTRHGYGKRTNKIEYPVRSRGILGVIAIKVNN-RNGNVVGSIQVDDDDEIMMITDCGRLVRIRASEINIFSRNTQGVLLIRTA
NNRLVSLQRVV-
>tr|E8Q739|E8Q739_BLOVB DNA gyrase subunit A OS=Blochmannia vafer (strain BVAF) GN=gyrA PE=3 SV=1
VENLINQRDVVVTLSYQGYVKYQPLTDYEAQKRGGKGLTTR-IKEEDFITQLLIANTHDTVLLFSNYGRIYWMKVYRLPEVKRSSRGRPIINLLPLD-NE
RITTILPIQKYTKGHQVFMATSSGFVKKTALMEFSRPRNVGIIALNLNVGDELIGADVTDGNNEVMLFTAYGKVVRFKETQVRSMGRSAVGVKGIHLL--
QGVVSLIIPKN-SSILTITKNGFGKRTDQSEYPLKSRSTKGVISIKVTE-RNGNVVGAVQVSHDDQIMIITDAGRLVRIRVSEVNIIKRNTKGVMLIRTA
CDHVVGLQRVV-
>tr|R6LP80|R6LP80_9FIRM DNA gyrase subunit A OS=Firmicutes bacterium CAG:170 GN=gyrA PE=3 SV=1
IEDLIEEEQCVFTLSHAGYIKRVPAATYRSQKRGGRGVTGQTL-DEDFVEGVFSASTHDYILFFTNMGRVHRRKGYQIPEG-RVAKGTNIVNILPLEAGE
KVTAGLTVR-F---DNLLFVTKQGTVKRVTLESLNTARKAGIRALTLADGDELIAVMKTNGSQNIVLATADGMAICFS---VRVMGRDAAGVRGIALS--
-YVVGAGIAEEGKQLLTVTELGYGKRTEITEYMRQLRGGKGLKNYNLTA-KTGRVAGVAVVG-DDDVMLIESGGVLIRMAASDIN-YKRDTQGVILMRLE
--RVISLEPVA-
>tr|Q0B0Y9|Q0B0Y9_SYNWW DNA gyrase subunit A OS=Syntrophomonas wolfei subsp. wolfei (strain DSM 2245B / Goettingen) GN=gyrA PE=3 SV=1
EEDFIDDHEVVITLSNRGYVKRQPLDTYRSQKRGGKGVSATTI-AEDFAHDVLVTSALATLLFFTNQGRVFTTRAFQIPE-SRQAKGMPLVNFLELRPGE
KVTTIVGAR-FR-EHHLLMVTKKGIIKKTALKAFQNVRKSGLIAVNLREDDELVGVIRVKTGSKVMIANSRGISIMFD---VRSMGRTAAGVKAINLS--
-YVVGLDRYR-GADVLLVTEKGYGKRTALSEFKLQNRGGKGLKAIEITR-RNGKLVAFQIVS-EDELVILTSEGNIIRLEVEDISQ-KRYSRGVLLMRLP
EERIVGVARFK-
>tr|K4LDX1|K4LDX1_THEPS DNA gyrase subunit A OS=Thermacetogenium phaeum (strain ATCC BAA-254 / DSM 12270 / PB) GN=gyrA PE=3 SV=1
KEDIIPEELVVITLTRRGYIKRIPLNTYRGQHRGGRGITALTT-DEDFVEQLFAASTHHFLLFFTNKGKVYRLKVYDIPES-RQAKGTALVNLLPLAA-E
VVTAVIPLR---DDRYLLMATRQGLVKKGLLSDYDS-RRDGIIALRLHPGDELIGVR-SEG-EEIILATKKGMALCFNE--VRVMGRAASGVLGIRLD--
-GVVGMDRFR--SQVLVVTERGYGKRTPAADYRVQKRGGRGLITLKVT-D-NGCLAGVKVVDR-DEILLMSSEDSMIRIRVGEIPVQGRNTQGVKLMRLK
DE-LVAVAKLP-
>tr|B5YGW5|B5YGW5_THEYD DNA gyrase subunit A OS=Thermodesulfovibrio yellowstonii (strain ATCC 51303 / DSM 11347 / YP87) GN=gyrA PE=3 SV=1
IEDLITQEDMVITLTHLGYIKRTSLSDYRSQKRGGKGLTPMET-TDDYLESVLIGSTHDHIMFFSNFGRVYCLKVYQIPEG-RVSKGKAIVNLLPLQEGE
KITTALVCK-I---GYLMMFTKKGFVKKTSLEEFKNIRQKGVIAIDLEEGDELISVRKTTGNNQLIIATKMGMAVRFS---VRPMGRTARGVIGIRFS--
-DVVSADVVSE-SFVLTITEKGIGKKTPIEEYRLQHRGGTGVKNIKLSL-KTGNVVSSLQVK-DDEIIICSS-SKMIRLKVSQIRP-GRATTGVRLIDLS
-DTVVSMGRIL-
>tr|R6IC64|R6IC64_9FIRM DNA gyrase subunit A OS=Firmicutes bacterium CAG:240 GN=gyrA PE=3 SV=1
IEDLIEEEDCVYTLTHNGYIKRLPTVEYRAQGRGGKGVKAMAT-EEDYVETVFTASTHDSILFFTNLGKVYVRKGYRIPE-GRSARGQNIVNIIPTDPGE
KVSAMIAGR-VE-DNYLVFVTRNGTVKRTAQSAFKNIRSNGIRALSLDEGDELISVLQTTGEDKILLATHDGMAICFA---ARAMGRDAVGVRGIRLR--
-YVVGAGIA--GAAILSITENGYGKRTDVGEYS-QNRGGMGLKNYNVTD-KTGPVADVVIVT-DEDLLVISDDGTIIRMDVGSISL-SRSTQGVRVMRLT
GDKVISIAPTD-
>tr|R6HUD3|R6HUD3_9FIRM DNA gyrase subunit A OS=Firmicutes bacterium CAG:137 GN=gyrA PE=3 SV=1
VEDLIEEEDCCYTLSSQGYIKRMPVDTYRSQRRGGRGINGQNL-EEDYVKSIFVASTHDYVLFFTDTGRVHKKKGYLIPES-RTARGTAIVNVLPLEPGE
KVTAMLLTR-F--NEYLMMVTKNGTVKRLAIQAVNTNRKAGIRALTLDEGDHLISVMKTSGNDRIILATAQGMAICFS---VRSMGRDAAGVKGITLA--
-YVVGAEKAEEDKSLLTVTANGYGKRTDIVEYLRQNRGGKGLKNYNITA-KTGPVVACRVVG-GEDVILIESGGVIIRMPASDIN-YKRDTQGVILMRVE
--QVIGVEKVD-
>tr|R5HAK8|R5HAK8_9FIRM DNA gyrase subunit A OS=Firmicutes bacterium CAG:114 GN=gyrA PE=3 SV=1
IEDLIEEETCVFTLTAAGYIKRMPVSTYRAQKRGGKGVSAQSL-EEDYVDTLFTASSHDNILFFTSSGRVYKKKGYQIPE-SRTAKGTHLNNIFQFEPGE
RVTAMLHGR-YE-NGYLFMVTRNGTVKRTEKSAFRNIRAAGLRGLTLDEGDELIAVLETDGEANVLIATHDGMAICFR---VRPMGRTAVGVRGIKLR--
-YVIGGVLA--GTTLLAITENGYGKRTHIEEYIRQHRGGFGLKGYQITE-KTGKAAGVKVVE-DDDILLISDDGTIIRMAAADVNL-SRTAQGVRVMRVS
EGKVISLARVP-
>tr|R5EQZ1|R5EQZ1_9FIRM DNA gyrase subunit A OS=Firmicutes bacterium CAG:110 GN=gyrA PE=3 SV=1
IEDLIEEETCAFTLSNQGYIKRMPVDTYRTQSRGGRGVNAQNL-EEDYVKSLTIASTHDHMLFFTDQGRVHHRKGYQIPE-GRTARGTAIVNVLPLNPGE
SVTAMVITR-FE-NEFLMMVTRKGTVKRIPFVSLKTNRKAGIRAITLDEDDHLINVIRTNGDDDIVLATAFGYAICFN---VRCMGRDAAGVRGIMLT--
-YVVGAEKA--GKTLLTVTQNGYGKRTALTEYLRQSRGGKGLKNYNITP-KTGNVAGCRVVS-SDDVMLIENGGVIIRIPASSINV-KRDVQGVIVMRID
DGQVVSLERVE-
>tr|R5D8R3|R5D8R3_9FIRM DNA gyrase subunit A OS=Firmicutes bacterium CAG:555 GN=gyrA PE=3 SV=1
IEDLIEEQECVYTLTHNGYIKRLPASEYRAQGRGGKGVRAMAT-DEDYVDTVFTASTHDSILFFTNKGKVYVRKGYRIPEG-RTARGSNIVNILPIEPGE
KVSAMIAGR---EDSYLMFITRDGTVKRTAQSLFKN-RSNGIRALTLDEGDELMTVL-TDG-KKILIATHGGMAICFDE--VRSMGRDAVGVRGIRLR--
-GVAGAGIAD--LTLLSITENGYGKRTEVSEYTVQNRGGMGLKNYNIT-E-TGNVADVKVVSS-DDLLVIADDGTIIRMDIASISVLGRSTQGVRVMRLN
GEKVISIALTD-
>tr|A0A096BE85|A0A096BE85_9FIRM DNA gyrase subunit A OS=Clostridium orbiscindens 1_3_50AFAA GN=gyrA PE=3 SV=1
IEDLIEEEECVFTLTAGGYIKRTAASTYKAQRRGGKGITAMST-EEDYVDTVFTASTHDFILFFTNKGRVHRKKGYQIPE-GRTARGTNLVNVLPIEQDE
KVTAMIHLR-FE-DRYLVMVTRSGTVKRIQLSSIYTARKAGIRCITLDEGDELICVRETDGDQAILIVTHDGMAICFK---VRCMGRDAAGVRGINLR--
-YVVGAARA--DHQVLMITENGYGKRTDMDEYIRQKRGGFGLKGYNVTE-KTGPVVGVKVVS-GDDVLVINDAGVIIRMAAAGIST-GRTAQGVKIMNLE
EGKVISFARTD-
>tr|R7FVD1|R7FVD1_9FIRM DNA gyrase subunit A OS=Eubacterium sp. CAG:841 GN=gyrA PE=3 SV=1
DEDLIERHDCVITMTCSGYIKRNPVDTYSAQNRGGKGIVGMTT-EEDAIKDVMVVHSHSYLLMFTSAGKVYMKKAYQIPES-RTAKGTNLVNVLELAEGE
KVTSIVSLN-F--DEYFVMVTKKGVIKRASTKDFEYQRKGGKIAINLDEGDELLAVKKTEGESDIIIATRKGKAVRFD---ARVMGRTARGVRGIRLK--
-DVVGVSVVEEGKKLITITEKGFGKRNDFDCFS-HSRGTMGVICHKLTA-KTGELAGIAAVS-DDDIMVITNEGTIIRMAVSSIP-YGSSTSGVIVMRLD
-EI-VNFAVTK-
>tr|R5ISH0|R5ISH0_9FIRM DNA gyrase subunit A OS=Firmicutes bacterium CAG:124 GN=gyrA PE=3 SV=1
IEDLIEEEQCVFTLSHAGYCKRVPASTYRSQKRGGRGVTGMTT-EEDFVEGVFTASTHDYILFFTNLGKVHRRKGYQIPEG-RTAKGTNLVNILPFEPGE
KVTAGITVH-F---DYLVFVTRNGTVKRLELASLNTARKAGIRALTLSEGDELIAVMKTDGKQDILLASANGMVICFN---VRVMGRDAAGVRGMMLD--
-YVVGAGIAAKGKQLLSVTEYGYGKRTEIEAYLRQNRGGKGLKGYNITA-KTGRIAGVAIVD-ADDIMLIENGGVLIRMAAADIN-YGRDTQGVILMRLE
--RVISVDRVD-
>tr|R8VTS5|R8VTS5_9CLOT DNA gyrase subunit A OS=Butyricicoccus pullicaecorum 1.2 GN=gyrA PE=3 SV=1
IEDLIEEQDSTYTLTHAGYIKRMPTSAYRAQRRGGRGVNAMAT-EEDFVRSIFNASTHDNILFFSNLGKVYKLKGYQIPEG-RAAKGQNIINLLEIEPGE
KITAMFPIRD--D-KYMVFVTKYGTIKRVVLSDLQNIRKVGLRALSLAEGDLLVDVRLTEGHENILIATHQGRAITFD---VRAMGRQAAGVRGIRLA--
-YVVGAARA--GAQVLSVTENGYGKRTLVEDFSIHHRGGGGILLHGLTD-KTGLVAGIAVVD-ENDIMMITDDGVIIRTPVEDIRQ-GRNSQGVIVMRTG
-DKVISIARTD-
>tr|A0A0C2Z8V3|A0A0C2Z8V3_9PROT DNA gyrase subunit A OS=Sulfurovum sp. AS07-7 GN=gyrA PE=3 SV=1
IEDLIPNEPMVVTITHRGYIKRVPVKQYEKQNRGGKGIAVT-T-DDDFIEKFFISNTHDTLMFVTDKGQLYWLKVYKIPEGSRTAKGKAVVNLINLQADE
KIMAIIPTT---ADKSLVFFTRNGIVKRTNLSEYSNIRSNGIRAIILDENDELVETH----TKYLFIATKKGMCIRFK---LREIGRVARGVTGIKFKA-
-DVCGATTINDQNEILMVSEKGIGKRTTASEYREQSRAGKGVISMKLT--KTGD-VVGVVVE-DKDLMCLTSIGKMIRVDSDTIRKAGRNTSGVIIVNVD
--KVVSIAKCP-
>tr|A0A0E1GNB3|A0A0E1GNB3_CAMFE DNA gyrase subunit A OS=Campylobacter fetus subsp. fetus 04/554 GN=gyrA PE=3 SV=1
VEDLIPNENMVVTITHRGYIKRVPSKSYEKQKRGGKGVAVT-T-DDDFIESFFTCMSHDTLMFVTDRGQLYWLKVYKIPEGSRTAKGKAVVNLISLQADE
KIKAIIPTT---ESKSLAFFTKNGIVKRTNLSEFKNIRSIGVKAINLDDNDELVTVVAN--GKMLFAVTKKGMCIKFA---VRQIGRVSRGVTAIRFKN-
-DVVGAVVIENSQEILSVSQKGIGKRTTADEYRLQSRGGKGVICMKLT--KTKDLVG-VVVD-EMDLMALTSSGKMIRVDMQSIRKAGRNTSGVIVVNVD
--EVVSIARCP-
>tr|L1MBA2|L1MBA2_9CORY DNA gyrase subunit A OS=Corynebacterium durum F0235 GN=gyrA PE=3 SV=1
EEDLIARENVVVTITSTGYAKRTKVDSYRNQKRGGKGVRGA-EKQDDVVRNFFVCSTHDWILFFTNYGRVYRLKAYELPEASRTARGQHVANLLEFQPGE
HIAQVIQIQ---AE-YLVLSTAHGRVKKSRLADYDS-RSGGLIAINLNE-DRLIGAA--SADDDLLLVSEEGQAIRFTD--LRPMGRATAGVKGMRFR-D
-DLLAMCVVR-GDYLLVATSGGYGKRTAMEEYPVKGRGGLGVVTFKYT-PKRGKLIGALAVDD-DQIFAITSAGGVIRTEVGQIRP-SRQTMGVRLVNLE
-DELFAIDRNV-
>tr|D5NX11|D5NX11_CORAM DNA gyrase subunit A OS=Corynebacterium ammoniagenes DSM 20306 GN=gyrA PE=3 SV=1
DEDLIARENVVVTITSTGYAKRTKVDSYKAQKRGGKGVRGA-EKQDDIVKNFFICSTHDWILFFTNFGRVYRLKAYELPEASRTARGQHVANLLEFQPEE
KIAQVIQIQ---AP-YLVLATKQGRVKKSRLTDYES-RSAGLIAINLNE-DSLIGAE--SDADDILLTSEQGQAIRFTE--LRPMGRATAGVKGMRFR-D
-DLLSLSVVQ-GGYLLVATSGGYGKRTAIEEYAPQGRGGLGVMTFKYT-PKRGKLIGAITVMD-DEIFAITSVGGVIRTEVNEIRP-SRATMGVRLVNLS
-DELLVIDRNV-
>tr|A0A0M4NSY9|A0A0M4NSY9_9GAMM DNA gyrase subunit A OS=Candidatus Thioglobus sp. EF1 GN=gyrA PE=3 SV=1
LEDLIAQEDRVVTLSHGGYVKAQSLSDYQAQRRGGKGAATK-MKDEDFVDQLFVANSHDTVLCFSSAGKVHWLKVYELPMASRTAKGKPIINLLPLE-DE
VINAILPVSEFSDDQFVFMVTSSGTCKKTSLTNFARPRKGGIIAIELRDGDKLVGVEITSGENDIMLFSANGKSIRFKEADVRAVGRTAIGVRGMKLVN-
-EIVSAIVADESSPILTATEKGYGKRTELEEYRSQARGGSGVISIKTSD-RNGKVVGAIQVTDEDEMMLISNKGTLVRARAADVSVIGRNTQGVTLINIS
KGKLVSVAKIA-
>tr|A5CXA3|A5CXA3_VESOH DNA gyrase subunit A OS=Vesicomyosocius okutanii subsp. Calyptogena okutanii (strain HA) GN=gyrA PE=3 SV=1
LEDLIAQEERVVTLSHGGYVKAQSLSDYQAQCRGGKGSATK-VKDEDFVDQLFIANSHDIVLCFSSFGKVYWLKVYDLPMASRISRGKPIINLLPLE-KE
IINAILPILKFDENHFVFMATSSGTCKKTALTNFSKPRKGGIIAIELRNNDQLIGVEITSGEHDIMLFSANGKSIRFKESDVRIVGRTAIGVRGIKLVD-
-DVVSLIVTNQDSPVLTATEKGFGKRTHLNEYRVQSRGGSGVISIKTSD-RNGKIIGAIQVTNEDEMMLISNKGILVRARAADVSIIGRNTQGVILINIS
KDKLVSIAKVV-
>tr|A1AVX7|A1AVX7_RUTMC DNA gyrase subunit A OS=Ruthia magnifica subsp. Calyptogena magnifica GN=gyrA PE=3 SV=1
LEDLITQERRVVTLSHGGYVKAQSLSDYQAQRRGGKGVATK-VKDEDFVDQLFIANSHDTVLCFSSLGKVYWLKVYELPMASRIARGKPIVNLLPLE-EE
IINAILTVSKFDENHFVFMVTSSGTCKKTVLTNFSKPRKGGIIAIELKDNDQLIGVEITSGEHDIMLFSANGKSIRFKESDVRVVGRTAIGVRGIKLAN-
-DVVSLIVVNQDNPILTTTEKGFGKRTRLNEYRSQARGGLGVISIKTSD-RNGKVVGAIQITDEDEMMLISNKGTLVRARAVDVSIIGRNTQGVTLINII
KGKLVSIAKIA-
>tr|A0A0M4LQC2|A0A0M4LQC2_9GAMM DNA gyrase subunit A OS=Candidatus Thioglobus singularis PS1 GN=gyrA PE=3 SV=1
LEDLIAQEDRVVTLSHGGYVKAQSLSDYHAQRRGGKGAATK-MKDEDFVDQLFVANSHDTVLCFSSTGKVHWLKVYELPMASRISRGKPIINLLPLD-DE
SINAILPVKEFTNDQFVFMVTSSGTCKKTSLQNFSRPRKGGIIAIELRDDDKLVGVEITAGEHDILLFSSAGKSIRFKESDVRSVGRTAIGVRGIRLSD-
-DVVSLIVAESDDPILTATEKGYGKRTQLDEYRTQARGGSGVISIKTSD-RNGQVVGAIQVTDEDEMMLISDKGTLVRARAADVSIIGRNTQGVTLINIA
DDALVSVAKIA-
>tr|A0A0D6AM29|A0A0D6AM29_9CHRO DNA gyrase subunit A OS=Geminocystis sp. NIES-3709 GN=gyrA PE=3 SV=1
DIDLIANERVVILLTNQGYLKKMLVNTFEAQNRATRGKSGAKI-DDDVVEHFLTGCDHDRVLFFSDKGVVYGLSAYQIPSSSRTARGVPIVQLLPVASDE
KITSVIPVS---DHEYLVMLTKKGFIKKTALSAFGNIRSNGLIAISLEDNDELRWVRLATEDDSVLIGSRRGMAIHFHA--LRPLGRTAKGVKSMKLR--
-QIISMDILPSAPWALAVTTSGYGKRVPVSQFRLQRRAGIGVKAIRF--P-KEELAALHIVN-DDEFMIITTRGIIIRCDVNAVSLQSRNASGVRVQKLD
-DAIAAIALVP-
>tr|K9Z2X7|K9Z2X7_CYAAP DNA gyrase subunit A OS=Cyanobacterium aponinum (strain PCC 10605) GN=gyrA PE=3 SV=1
DIDLIANEQVAIILTNQGYLKKMLVNTFEAQNRATRGKSGAKI-EDDVVEHFLTGCDHDRILFFSDKGVVYGLNAYQLPALSRNARGVPIVQMLPIASDE
KITSMIAVS---DHEYLVMLTQKGLIKKTALSAFANIRSNGLIAISLGEGDELRWVRLATEDDSILIGSRQGMAIHFHA--LRPLSRTAKGVKSMKLR--
-EIISMDILPSAPWALAVTTSGFGKRVPVSQFRLQRRAGMGLKAIRF--K-SDALAALRIVN-EDEFMIITTRGIIIRCDVNAVSLQSRQASGVRVQKLD
-EAIAAIALVP-
>tr|K9YRM2|K9YRM2_CYASC DNA gyrase subunit A OS=Cyanobacterium stanieri (strain ATCC 29140 / PCC 7202) GN=gyrA PE=3 SV=1
DIDLIANEQVAIILTEQGYLKKMLVSTFEAQNRATRGKAGAKI-DDDEVQHFLTGCEHDTILFFSDRGVVYALNAYQIPSSSRNARGMPIIQMLPISSEE
KITSILAVS---DHEYLVMLTRNGFIKKTALSAFGNIRSNGLIAISLAEGDELRWVRLATADDSILIGSRRGMAIHFHA--LRPLSRTAKGVKSMKLR--
-QLISMDIIPSAPWALAVTTSGYGKRVPVSQFRLQRRAGLGLKAIRF--S-NEELAALHIVN-DDEFMIITARGIIIRCDVNAVSLQSRNASGVRVQKLD
-DAIAAVALVP-
>tr|R4VT72|R4VT72_9EURY DNA gyrase subunit A OS=Salinarchaeum sp. Harcht-Bsk1 GN=gyrA PE=3 SV=1
HEDLIPEEESVFVLTEQDYVKRMPAARFDDQRRGGKGVIGADV-EGDRVSRVFTANTHDHLLWFTESGEVYETRGFEIPEMGRTARGTAAINFLDLEDGE
TIATVLA---I-TDGYVVTATKNGYVKRTVATAFENVLSTGIIAADVDPDDAIVDVA-TSGDDDLLIASEQGMAIRFPE--ARAMGRSARGVGGIELV--
-DVAGVTAIDD-GELLTVTRNGYGKRTKLTEYRPQSRNGKGLVDI--VR--NGPTVAVEAVDADDHLVLYSEDGQIMRTRAADVSVVGRNTMGVIVMGIE
-GAVADVAVLD-
>tr|A0A0F9K7J8|A0A0F9K7J8_9ZZZZ Uncharacterized protein (Fragment) OS=marine sediment metagenome GN=LCGC14_1363040 PE=4 SV=1
LEDLISEEEMVVTLSHAGYAKTQQLDTYQAQRRGGKGSATA-MKDEDFIEHLFIANTHDTLLCFSSTGKVYWKKVYELPQGGRAARGKPIVNILP-LEGE
NINAILAVRDFDADQYIFMVTASGTVKKTPLEAYSRPRANGIIAVDLKDDDQLISVALTDGQSDIMLFSSNGKVIRFPETDVRSMGRVSRGVRGMRLPEV
D-IISMIIANPEGAILTATEFGFGKRTDLEQYRVQGRGGSGIISIQTSE-RNGNVVGAVQVQPEHQIMLITNGGTLVRTPVKDVSIVGRNTQGVKLINLT
KKKLVGLERVL-
>tr|A0A091G0Z1|A0A091G0Z1_9DELT DNA gyrase subunit A OS=Smithella sp. SCADC GN=gyrA PE=3 SV=1
IEDMIVEEDVVVTISHTGYIKRNAVSLYKSQHRGGRGKMGMGT-EEDFVEKIFIASTHHYLLVFTSAGKVHWLKVYQIPQAGRAAKGKAMINLVNLAP-E
SVRATLPVK----DKFIVMVTKKGTIKKTELAAYAN-RSGGIIAISIDEGDELVDVQ-TMG-QDIFIASRLGMAIRFKE--VRDMGRTARGVRGINLD--
DDVIGMDIPAQNTFMLTVSENGFGKCTPIDEYRVQTRGGKGTINLKTV-E-VGNVSGVLQVIE-DNVMLISNAGKVIRLKVQEIPVNHRVTQGVKLIELD
-EKLVGVARTT-
>tr|A0A091AFW7|A0A091AFW7_9DELT DNA gyrase subunit A OS=Smithella sp. F21 GN=gyrA PE=3 SV=1
IEDMIVEEDMVVTISHAGYIKRNAVSLYKSQHRGGRGKVGMGT-EEDFVEKIFIASTHHYLLVFTNMGKVYWLKVYQIPQAGRAAKGKAMVNLVNLAP-E
KVSATLPVK----DKFIIMVTKKGIVKKTDLAAYSN-RAGGIIAISIDEGDELVDVQ-TMG-QDVFLGTRLGMAIRFNE--VRDTGRTARGVRGINLD--
DDVIGVEIPAQGTFMLTISENGFGKCTPIDEYRVQTRGGKGTINLKTV-A-IGNVSGVLQVQE-ENIMLISNAGKVIRLKVQEVPINHRVTQGVKLIDLE
-EKLVGVARTT-
>tr|Q3JEP2|Q3JEP2_NITOC DNA gyrase subunit A OS=Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848) GN=gyrA PE=3 SV=1
LEDLIQEENVVVTLSHSGYAKSQTLDTYRSQKRGGKGSATA-MKEEDFIDKLFIANTHDTLLCFSSRGKVYWKKVYELPQGSRVARGKPFVNLLPLE-GE
RINTVLSIREFEKDKYIFMVTASGVVKKTSLADFSRPRSSGIIALDLREGDQLVGADLTDGVQEIMLFSSGGKVIRFSERDVRPVGRTARGVKGMELPSH
R-VIALIIAA-SGTILTATELGYGKRTAIAEYRLQGRGGRGIISIRTTP-RNGEVVGAVQVEKEDEVVLISDGGTLIRTPVDNISLMGRNTQGVKLINLQ
EGRLVGIERIV-
>tr|S5T9F0|S5T9F0_9GAMM DNA gyrase subunit A OS=Cycloclasticus zancles 78-ME GN=gyrA PE=3 SV=1
AEDLITEEDMVVTLSHEGYVKSQPLTSYTAQRRGGKGTAAN-TKNEDFIDKLFIANTHDTVLCFSSKGKVYWLRVFNLPVASRVARGKPIVNLLPLD-DE
RINAILPIREFNEDEYIFMATESGTVKKTHIKEFEKPRANGKIAIDLRDDDTLVGVAVTDGEKDVMLFASSGKVASFKEADVRVMGRTASGVRGMRLKDE
H-IISLIISE-PGTVLTLTQNGYGKRTKIEEYPIHKRGGQGVIAMQTSE-RNGALVGAVLVDESDELMLITDGGTLVRTRTSEISILGRNTQGVRVIRPA
KNKVIGLDRIA-
>tr|I1YEH0|I1YEH0_METFJ DNA gyrase subunit A OS=Methylophaga frappieri (strain ATCC BAA-2434 / DSM 25690 / JAM7) GN=gyrA PE=3 SV=1
LEDLICEEEMVVTLSHAGYAKTTQLDTYQAQRRGGKGAATS-MKDEDFVEHLFIANTHDTLLCFSSAGKVYWKKVYELPQGGRTARGKPIVNLLPLE-GE
RINAVLPIREFEADKFIFMATASGTVKKTPLVDYSRPRANGIIAVDLKEDDVLVDVALTDGASDVMLFSTNGKVIRFPETDVRSMGRVSRGVRGMRLTDE
K-IISLIIAR-EGAILTATEFGFGKRTHLDEYRVQGRGGQGIISIQTSA-RNGQVVGAVQVDDEDQIMMITNGGTLVRTPVKHVSLVGRNTQGVKLINLT
KDRLVGVERVI-
>tr|U1PMA5|U1PMA5_9EURY DNA gyrase subunit A OS=Haloquadratum walsbyi J07HQW2 GN=gyrA PE=3 SV=1
HEDLIEQENVIVVVTEDDYIKRMSVEDFRSQHRGGKGIIGTSL-DGDNVSSVYVANTHDYLLYFTSHGQVYQLKTYQIPEMSRTARGKSAVNLLELDDGE
EITAVVNTA---NERYFTMVTQSGYIKRTSVNSFQNIRATGIIAIDLDADDELIDVEVTDGSQDIILGTRKGMAIRFDE--VRSMGRSARGVHGIKLE--
-AVAALAAIDEDEWVLTVTEHGYGKRTNIDRYRQQSRNGKGLIDI--ND-RNGRVCEVETVGADSELFIMSRNGQILRTPVSDISTVGRNTSGVIVMDLD
-NTVASVDIHP-
>tr|G0LLH1|G0LLH1_HALWC DNA gyrase subunit A OS=Haloquadratum walsbyi (strain DSM 16854 / JCM 12705 / C23) GN=gyrA PE=3 SV=1
HEDLIAQEDVVVVVTEDDYIKRMSLEDFRSQHRGGKGIIGTSL-DGDTVSSVYVANTHDYLLYFTSHGQVYQLKTYQIPEMSRTARGKSAVNLLELDDGE
QITAVVNTA---EERYFTMVTQSGYIKRTSVNSFQNIRSTGIIAISLGADDKLIDVEVTDGNQDIILGTRKGMAIRFNE--VRSVGRSARGVHGIKLE--
-AVAALAAVDDDDWVLTVTEHGYGKRTDIDRYRQQSRNGKGLIDI--NE-RNGHICEVETVGISDELFMMSRKGQILRTPVDDISTVGRNTMGVIVMDLE
-TTVASVDTHP-
>tr|D0L0F0|D0L0F0_HALNC DNA gyrase subunit A OS=Halothiobacillus neapolitanus (strain ATCC 23641 / c2) GN=gyrA PE=3 SV=1
IEDLIAEEDRVVTLSREGYIKTQSLSEYQSQRRGGRGSSTR-MKDEDVIEQLMVASTHAWALMFTNLGRVYWRKVYQLPQGARGARGRPVVNILPLQ-GE
RVNALLPVREFVDDHYIFFATATGQVKKTPLVDFSRPRQAGIIAIDLRDDDRLVGARLTDGSRELMLFSNAGKSIRFAEADVRSMGRTAGGVRGIRMDE-
-QVVSLLV-VGEGQVLTATEHGYGKRTPIDDFPLQGRGGQGVIAIQTSE-RNGALVGAALVQDEDEVILISDAGTLVRTEISQISSVSRNTQGVILIRLS
DDKLVQLAAVS-
>tr|A0A088STP4|A0A088STP4_9GAMM DNA topoisomerase (ATP-hydrolyzing) (Fragment) OS=Acidithiobacillus caldus GN=gyrA PE=3 SV=1
NEDLIAEENMVVTFTHAGYIKAQPVTTFNAQRRGGRGVATT-TKEEDFVERMFCASTHATVLFFSNLGKVFWQKVYQLPQSGRSARGKPIVNLLSLA-SE
GITTVLPVREFQEGQYVCMVTAHGVVKKTPLMEYSRPRSQGINAINLDPGDRLVAVCLSDGQREFMLFTRKGMAVRFPEDKVRPMGRTARGVRGISLDA-
-DVISAQIVDPDQVILTATAKGYGKLTNVEEYRRTNRGGKGVIAIQTNA-RNGQVVGALAVKESDELMLVSNGGTLIRIAVQGIRRTGRNAQGVRLIQLA
PDQLAGLALIA-
>tr|A0A0R2AW55|A0A0R2AW55_9LACO DNA gyrase subunit alpha OS=Lactobacillus brantae DSM 23927 GN=FC34_GL001335 PE=4 SV=1
DEDLIEEEDVVIALTHNGYVKRLPATEFKSQNRGGRGIQGMGV-DDDFMEHLVSTSTHDMLLFFTNTGKVYRNKGYEIPEYGRTAKGIPIINLLGI-DGE
KVQTVINVD--NSERFLFFVTRNGVVKRTPVSDFAN-RSNGLIALNLKDDDELSNVI-TDG-DTIFIGTHRGYSVTFKE--VRSMGRSATGVRGIRLR--
-EVVGSDVLAPDSEVFVISENGYGKRTSASEYPTKGRGGKGIKTANIT-E-NGPLAGVTTVND-EDILVMTDAGVMIRFSVASVSQTGRSTLGVRLIRVD
D-KVATMAKVE-
>tr|G6CDQ2|G6CDQ2_LACCU DNA gyrase subunit A OS=Lactobacillus curvatus CRL 705 GN=gyrA PE=3 SV=1
DEDLIEEEDVVIALTHNGYIKRLPASEFKVQNRGGRGIQGMGV-DDDFIEHLLSTSTHEVLLFFTNTGKVYRAKGYEIPEYGRTAKGIPIINLLGI-NDE
RVQTVVNVG--QDEQSLFFITRLGTVKRTSVSEFAN-RSNGLKALTLREEDELSNVL-TDG-QNIFIGTHNGYAVSFSE--VRSMGRTAAGVRGIRLR--
-GVVGSDLLIPGQEILVISEKGYGKRTPVADYPIKGRGGKGIKTANIT-E-NGPLAGIAAVTE-EDILLITDTGVLIRFKVANVSQTGRATLGVRLIRVD
E-KVATMAKVE-
>tr|A0A0P8BWU5|A0A0P8BWU5_9CYAN DNA gyrase, A subunit OS=Phormidium sp. OSCR GN=gyrA PE=4 SV=1
DTDLIANEQALILVTEQGYIKRMPVNTFEAQNRATRGKSGTKM-EDDGIAHFLTCCDHDQILFFSDRGVVYSVKAYQIPTGSRTSRGIPIVQLLPIPRDE
KITSVVPVS---DDNYLIMLTRGGNIKKTALSAFANIRANGLIAISLSDGDELRWVRLARAEDSIIIGSRLGMAIHFKA--LRPLGRATRGVKSMNLR--
-DLISMDVLPSGPWVLIVTTGGYGKRVPVSQFRLQRRAGKGTISTKFHLK-DDSVVGLIVVN-DDELMMVTMRGIIIRQAASAITPQSRSATGIRVQRLD
-DAIAAVAIVP-
>tr|A4AEW7|A4AEW7_9ACTN DNA gyrase subunit A OS=marine actinobacterium PHSC20C1 GN=gyrA PE=3 SV=1
MEDLIPEEEMVVTVTRGGYVKRTRSDNYRSQHRGGKGVKGA-QRADDIVDHLFVTTTHHWLLFFTNTGRVYRAKAYELQEGGRDAKGQHVANFLALQPGE
EIAQILDIR---AT-YLVLATHNGLVKKTALSEYDT-RSGGIIAVNLREGDELVSAM--ENTDDVLLVSRKGMSIRFTE--LRPMGRSTSGVMGMSFR-D
-DLLSASVVP-SGYVFVVTEGGFAKRTSADQYRVQGRGGLGIKVAKLD-G-RGDLAGALMVGH-DEVLVVLASGKVVRSSVAEVPA-GRDTMGVVFARFA
-EKIIAIARNS-
>tr|A0A061LUJ5|A0A061LUJ5_9MICO DNA gyrase subunit A OS=Leucobacter sp. UCD-THU GN=gyrA PE=3 SV=1
MEDLIPEEEMVVTVTRGGYVKRTRIDNYRSQHRGGKGVKGA-QRADDIIEHFFVTTTHHWLLFFTNTGRVYRAKTYEVPEGGRDSKGQHLANLLALAPDE
TVTQILDVR---AG-YLVLATRDGLVKKTALPEYDT-RTGGIIAIKLREGDELVSAL--ESSDDVLLVSKHGMSVRFTQ--LRPMGRSTSGVRGMNFR-G
-DLLSASRINGEGYVFVVTEGGYAKRTAVDEYRVQNRGGYGIKVAKLD-E-RGDLVGALIVET-DEVLAVLASGKVVRSAVAEVPA-GRNTMGVVFARFP
-RRIIGIARNT-
>tr|A0A075U492|A0A075U492_9LACT DNA gyrase subunit A OS=Weissella ceti GN=gyrA PE=3 SV=1
DEDLIEEEDVIVSLTRGGYIKRMAQSEFRAQNRGGRGVQGMGV-DDDFIDQIAGTSTHDTLLFFTNAGKVYKLKGYEIPEYGRTAKGIPVINLLGI-EGE
TIQTMISVN--NSDDYLFFTTRDGVVKRTAISEFGN-RAHGLRAINLRENDELIKVM-TVD-DNILIATQGGYAVSFKM--IRAMGRTAAGVRGINLR--
-NVIGAEVLVDDAHVLVITQNGYGKKTAVSEYPIKGRGGKGIKTAQIT-E-NGPLAGVAVVQG-EDVVLTTNMGVMIRFNVATVSETGRATQGVRLIRLD
E-TVATFTTVE-
>tr|A0A0R2FVZ8|A0A0R2FVZ8_9LACT DNA gyrase subunit A OS=Weissella halotolerans DSM 20190 GN=IV68_GL000506 PE=4 SV=1
DEDLIEQEDIIVSLTHEGYIKRMAQSEFRAQNRGGRGVQGMGV-SNDFIDKIVGASTHDTLLFFTNSGKVYRLKGYEIPEYGRSAKGIPVINLLGI-SGE
AIQTVINIH--ASEDDLFFTTRDGVVKRTPISEFSN-RNNGLRAINLHEDDELINVM-TDG-HNVLLGTHGGYAVSFNV--VRSMGRSAAGVRGIRLR--
-DVVGAQVLEPEDDVLVITENGYGKMTPASEYPIKGRGGKGIKTAQVT-E-NGPLVGVSVVKH-EDVILTTNLGVMIRFNVDNVSLTGRATQGVRLIRLD
D-KVATFTTVA-
>tr|A0A069CYN9|A0A069CYN9_9LACT DNA gyrase subunit A OS=Weissella oryzae SG25 GN=gyrA PE=3 SV=1
DEDLIEEEDVFVTLTNNGYIKRMVTTEFRAQNRGGRGIQGMGV-DDDFIEQLVSTSTHDTLLFFTNMGKVYKMKGYEVPEYGRTAKGIPVVNLLGI-EGE
KVQAVLNVR--ESKDYIFFTTREGVVKRTPVTEFSN-RTHGLRAINLHDSDELISAQ-TDG-QKILIGTHGGYAVSFQE--VRSMGRSAAGVRGINLR--
-DVIGAEVLPADSKVLVITENGYGKQTASDEYPTKGRGGKGIKTAQIT-T-NGPLAGITVVNN-EDIMLTTNKGVMIRFTADSVSETGRATQGVRLIRLD
D-KVATLAKVE-
>tr|F8I199|F8I199_WEIKK DNA gyrase subunit A OS=Weissella koreensis (strain KACC 15510) GN=gyrA PE=3 SV=1
DEDLIEEEEIVVTLTNGGYIKRVPTSEFRAQNRGGRGVQGMGL-DDDYIDQLIGTSTHDTLLFFTSLGKVYRMKGYEIPEYGRTAKGIPVINLLGKLDNE
QVTKIINVR--ESNDYLFFVTQQGVVKRTSVSEFGN-RTNGLKALTLHDEDELIAVL-SDG-QEIFIGTHDGYSVSFSE--VRSMGRSAAGVRGIRLR--
-GVVGADVRHDGDEVLVITENGYGKRTSVSEYPVKGRGGKGIKTANIT-D-NGSLVGISIVSD-EDVMLTTDQGVMIRFTVDSVSQTGRATQGVRLMRLG
E-KVATFTKMD-
>tr|A0A0R2H9I9|A0A0R2H9I9_WEIVI DNA gyrase subunit A OS=Weissella viridescens GN=IV50_GL000528 PE=4 SV=1
DEDLIEEEDVIVSLTRGGYIKRMAQSEFRSQNRGGRGVQGMGV-DDDFIDQMVSSSTHDTLLFFTNTGRVYRLKGYEVPEYSRTAKGIPVVNLLGL-DDE
SIQTVISVQ--ESEDYLFFTTRQGVVKRTPVSDFGN-RTSGLRAINLRDEDELINVL-ANG-SNILIGTHNGYAVSFNS--VRSMGRTAAGVRGINLR--
-DVIGAQALEDDKYVLVITENGYGKKTPVSEYPIKGRGGKGIKTAQIT-E-NGPVAGIAVVDD-EDIMLTTNMGVMIRFSVDAVSETGRATQGVRLIRLD
D-KVATFTTVD-
>tr|A0A0R2JJC4|A0A0R2JJC4_9LACT Uncharacterized protein OS=Weissella kandleri GN=IV73_GL000350 PE=4 SV=1
DEDLIEEEEIIVTLTNGGYIKRVPANEFRSQNRGGRGVQGMGL-DDDYIDQLIGTSTHDTLLFFTSLGKVYRMKGYEIPEYGRTAKGIPVINLLGKLDNE
QVTKVINVR--DSKDYLFFVTRQGVVKRTPIADFSN-RTNGLKALTLHDDDELIAVL-SDG-QEIFIGTHNGYSVSFNE--VRSMSRAAAGVRGIRLR--
-GVVGADVRHADEEVLVITENGYGKRTAIGEYPIKGRGGKGIKTANIT-E-NGPLVGVVVVKS-EDIMLTTDQGVMIRFTVDTVSQTGRSAQGVRLMRLG
E-KVATFTKIE-
>tr|C5R9Y7|C5R9Y7_WEIPA DNA gyrase subunit A OS=Weissella paramesenteroides ATCC 33313 GN=gyrA PE=3 SV=1
DEDLIEEEDIIVSLTHAGYIKRMLQSEFRAQNRGGRGIQGMGV-DDDFIDELIGTSTHDTLLFFTNSGKVYKMKGYEVPEYGRTAKGIPVVNLLGI-EGE
SIQTVINVR--ESSDYLFFTTRQGVVKRTPVNEFGN-RAHGLKAINLHDGDELINVL-TDG-QNIIIGTHGGYAVSFNS--VRSMGRSAAGVRGITLR--
-DVVGAQVLIDNGHVLIITEKGYGKQTPVDQYPIKGRGGKGIKTAQVT-E-NGPLAGLKVVDS-EDIMLTTNKGVMIRFTVDSISETGRATQGVRVIRLD
D-AVATFAKVE-
>tr|A0A0N7HAG7|A0A0N7HAG7_9LACT DNA gyrase subunit A OS=Weissella cibaria GN=AO080_01925 PE=4 SV=1
DEDLIEEEDIIVSLTSAGYIKRMAQTEFRAQNRGGRGVQGMGV-DDDFIDQLIGTSTHDTLLFFTNAGKVYKMKGYEIPEYGRSAKGIPVVNLLGI-EGE
SVQTVINVR--ESEDFLFFTTRYGKVKKTPVSDFSN-RTHGLKAITLNDDDELINVM-TDG-ENLLIGTHGGYAVSFNA--VRSMGRSAAGVRGITLR--
-DVIGAEILKDDASVLVITEKGYGKQTPVDQYPIKGRGGKGIKTAQIT-E-NGPLAGLAVVDS-EDIMLTTNKGVMIRFTVDSVSETGRATQGVRVIRLD
D-IVATFAKVE-
>tr|R9JKQ8|R9JKQ8_9FIRM DNA gyrase subunit A OS=Lachnospiraceae bacterium A4 GN=gyrA PE=3 SV=1
MEDLIPRGNTVIAMTSLGYIKRMTVDNFKTQHRGGRGIKGMST-EDDYIEDLLMTTTHHYLMFFTNFGRVYRLKTYEIPEAGRTARGTAIVNLLQLNP-E
KISAMIPIR---EGKHLFMVTKRGITKKTPIMEFSN-RKNGLAAISLRDDDELIEVK-TDE-SEIFLITKYGMCIRFKE--VRAMGRNAMGVIGMNLD--
-GIIGMQLNTQGDALLIVSEMGMGKRTLLDEFTVQKRGGKGVRCYRIT-E-TGNVVGIKGVND-HEVMMITTEGVIIQIPVGDISIYGRNTSGVKLINLD
ENKVAKIAKVR-
>tr|R9MN66|R9MN66_9FIRM DNA gyrase subunit A OS=Lachnospiraceae bacterium 10-1 GN=gyrA PE=3 SV=1
MEDMIPDENTIIAMSNLGYIKRMTIDNFKSQNRGGKGIKGMQT-EDDFIADLLMTTTHHYIMFFTNYGRVYRLKTYEIPEASRTSRGIAIVNILQLNP-E
KISAIIPVK---KNKNLFMVTKNGIVKKTSIIEYSN-RKNGLAAINLRDDDELIEVK-TDK-TEIFLVTKYGMCIRFRE--VRATGRSSMGVIGMNLG--
-GIVGMQLDHQGDSLLIVSENGMGKRTYLDEFTVQKRGGKGIKCYKIT-E-TGDVIGVKAVND-HEIMMITTGGIIIQIRMEDISKLGRITSGVKLINLD
-GTVAQIAKVR-
>tr|R9KRX1|R9KRX1_9FIRM DNA gyrase subunit A OS=Lachnospiraceae bacterium COE1 GN=gyrA PE=3 SV=1
MEDLIPRGNTIIAMTSLGYIKRMTVDNFKTQHRGGRGIKGMST-EDDYIEDLLMTTTHHYLMFFTNFGRVYRIKAYEIPEAGRTARGTAIVNILQLNP-E
KITAMIPIS---DGKHLFMITKKGIAKKTPIMEFSN-RKSGLAAISLRDDDELIEVK-TDE-SEIFLVTKYGMCIRFKE--VRSMGRGAMGVIGMNLD--
-GIVGMQLNTQGERLLIVSEMGMGKRTNIDEFTVQKRGGKGIKCYRIA-E-TGNVVGVKAVKD-SEVMMITTEGVIIQISVEDISIYKRNTSGVKMINLD
-GTVAKVAKVK-
>tr|R7R767|R7R767_9FIRM DNA gyrase subunit A OS=Roseburia sp. CAG:100 GN=gyrA PE=3 SV=1
MEDLIPRENTVIAMTSLGYIKRMTVDNFKTQNRGGRGIKGMST-DDDYIEDLLMTTTHHYLMFFTNYGRVYRLKAYEIPEAGRTARGTAIINLLQLTP-E
KISAMIPIS---EGKNLFMITKNGIAKKTPVIEFSN-RKTGLAAINLREDDELIEVK-TDA-SEIFLVTKYGMCIRFKE--VRAMGRTAMGVIGMNLE--
-GIVGMQLNTQGDSLLIVSEKGMGKRTRMDEFSVQKRGGKGVKCYKIA-D-TGNVIGVKAVNS-HEIMMITTEGIIIQLRMEDISMIGRNTSGVKMINLD
-GTVARIAKVR-
>tr|R7N2R5|R7N2R5_9FIRM DNA gyrase subunit A OS=Firmicutes bacterium CAG:95 GN=gyrA PE=3 SV=1
VEDMIPNENTIIAMSNLGYVKRMTIDNFKSQHRGGKGIKGMQT-EDDFIADLLMTTTHHYIMFFTNFGRVYRLKTYEIPESGRTSRGVAIVNLLQLNP-E
KVSAIIPIK---ENKNLFMVTRKGIVKKTSVVEYSN-RKNGLTAINLREDDELIEVK-TDK-TEIILVTRFGMCIRFKE--VRSTGRASMGVIGMSLN--
-QIVGMQLDHQGDSLLIVSEKGMGKRTFLEEFTVQKRGGKGVKCYKIT-D-TGYVVGVKAVNE-NEIMLITTGGIIIQIPMSDVSILGRITSGVKLINLD
G-TVAQIAKVR-
>tr|Q11UG4|Q11UG4_CYTH3 DNA gyrase subunit A OS=Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469) GN=gyrA PE=3 SV=1
IEDMIPEEQMVITISHEGYIKRTALSEYRTQGRGGVGSKGAGS-ESDFTEHLFVASTHNYLLFFTEYGKVFWLKVYEIPEGGKTTKGRAIQNVIQIEPGD
KVRTVINVKT--NNNYLVMCTEQGVIKKTTLEAYSR-RSGGINAITIHEGDRLLDVKMTSGSDELVIALRSGRAIRFN---VRPMGRTAAGVKGVTLAD-
-DVVGLVAVSSDTTLLVVSEKGYGKRSDIEDYRVTNRGGKGVKTLNISE-KTGDLVSILGVN-QYQIMIINKSGITIRMAVSDLRVMGRATQGVRLIKIQ
-GSIASVAKFE-
>tr|A0A0Q4B9F6|A0A0Q4B9F6_9BACE DNA gyrase subunit A OS=Candidatus Bacteroides periocalifornicus GN=AL399_00775 PE=4 SV=1
PEDFYPDDDVVITISHLGYIKRTNLAEYRAQKRGGKGAKGSAT-DEDFIEHLFNTTMHHTLLFFTESGRCYWLKGYEVPEGARDSKGRTLQNLISISPDD
KVRAIINVRD--SSHYVVMCTRCGVVKKTLLSEYSR-RSTGIIAVNIREQDQLLEAVLTDGQGELMLASRHGQAVRFN---LRALGRNSTGVIGMRLE--
-DVVGMVAVQPERTLLVVSDSGFCKRSPID-YRKTNRGSKGVKTLNVA--KAGEVVGISLVS-DEDLMIISRNGVIIRFPVAQTHVASRNTKGVHCIALG
-GTIASISPVA-
>tr|D2QCP2|D2QCP2_SPILD DNA gyrase subunit A OS=Spirosoma linguale (strain ATCC 33905 / DSM 74 / LMG 10896) GN=gyrA PE=3 SV=1
DLSLIADEDMVITISHEGYIKRTPTTEYRSQGRGGVGAKAAST-EEDFTEHLFTATMHNTLLAFTQKGRMYWLPVYELPEGSRTSKGRPLANFINIESDD
KVRAVINVTK--NNNYIVMCTRKGTIKKTMLEAYSR-RQNGIIAITIDEDDQLLGVCMTNGDNDIVIASSAGKAVRFH---VRPMGRTAAGVRGISLDEP
-DVIGMVCISSDAQLLVVSQNGYGKRSDIDGYRITNRGAKGVGTLKITE-KVGRLVAVLDVA-NDDLMIINKSGIAIRTPVDAINVIGRNTQGVRLIKLN
-GEISSVTKIK-
>tr|A0A0N0CZ00|A0A0N0CZ00_9BACT DNA gyrase subunit A OS=bacterium 336/3 GN=gyrA PE=3 SV=1
DEDMIANEQVVITISHQGYIKRTVLTEYRVQGRGGVGSKGVTT-QDDFTEHMFVATNHNYLLIFTESGKVFWKKVYEIPEGSKTAQGRAIQNLIQIEQGD
KVRAVINVES--NNHFLIMCTEKGTIKKTTLEAYSR-RANGINAININEGDKLIEVRMTTGSDHIILATKSGRAIHFH---VRPMGRTATGVRGIWLDQP
-DVIGMVCVGSDTNLLVVSERGYGKRSDTTEYRITSRGGKGVKAMSVTE-KTGKLVAIKDVS-TDDLMIINKSGITIRMKVETLRVQGRATQGVRLITLN
-EEISSIAKIE-
>tr|I2GHM1|I2GHM1_9BACT DNA gyrase subunit A OS=Fibrisoma limi BUZ 3 GN=gyrA PE=3 SV=1
DLSLIADEEMLITISHEGYVKRTPLSEYRTQGRGGVGAKAVVT-DEDFTEHLFTATMHNTLLIFTQKGRLYWLPVYKLPEGTRTAKGRPLANFINIESDD
KVRAVINVKD--NNNYVVMCTRQGTIKKTLLEAYSR-RQNGIIAITIDEDDQLLGVCLTNGDNEIVIASSAGKAVRFH---VRPMGRTAAGVRAITLDES
-DVVGMVCIDSDAQLLVVSEKGYGKRSEIDEYRVTNRGAKGVGTLKVTD-KVGKLVAVLDVT-NDDLMIINRSGIAIRMAVSDVSVIGRNTQGVRLIRLN
-GEISSVTKIE-
>tr|A0A0L8ANA8|A0A0L8ANA8_9BACT DNA gyrase subunit A OS=Roseivirga sp. D-25 GN=gyrA PE=3 SV=1
AEDMIPNEEMLITISHLGYVKRTLLSEYKTQGRGGVGSKGAGS-TDDFTEYLFTGMTHDYLLIFTEFGKVFWKKVWELPEGNKTAKGRPVQNLINIEPGD
RIRAVINVQK--NNNYVVMCTELGTIKKTSLEAYSR-RTNGINAITINEGDRLLEVKFTNGDNHIIIGARSGRAIHFH---VRPMGRTAAGVRAFRLAD-
-DVIGMVCVNREANLLVVSENGYGKRSPIDDYRITKRGGKGVKTINVTE-KTGNLVAIKEVV-SDDLMIINKSGITIRISVESLRVMGRATQGVKLIRLN
-GAISSVEKIQ-
>tr|A0A0D3LAX6|A0A0D3LAX6_9BACT DNA gyrase subunit A OS=Flammeovirgaceae bacterium 311 GN=gyrA PE=3 SV=1
MEDMIPNEKVVITISHQGYMKRTQLVEYRTQGRGGVGSRGVST-VDDFTEHLFIANTHNYLLIFTENGKVYWIKVYEIPEGSKVSKGRAVQNIINIEPGD
RVRAVLNVEK--NNNFIMMCTVQGTIKKTTLEAYSR-RQNGVNAITINPGDRLLDVKMTNGDNHIVLGLESGRAIHFH---VRPMGRTAAGVRGIAVGE-
-DVIGMVCVARDASLLVVTEHGYGKRSVVEEYRITRRGGKGVKALKISE-KTGKLVAIKEVI-TDELMIINRSGITIRMKVDDLRIMGRATQGVRLIRLN
-NSISSVEKIE-
>tr|A0A0E3ZH86|A0A0E3ZH86_9BACT DNA gyrase subunit A OS=Pontibacter korlensis GN=gyrA PE=3 SV=1
YEDMIPEENMVITISHEGYIKRTSLNEYRSQSRGGVGSRGVAS-ESDFTEHLFIANTHHHMLFFTEFGRVFWLKVYEIPEGGKTTKGRAIQNLIQIERDD
KVRAVLNVHK--LNHNLVFITEQGTIKKTVLEAYSR-RTNGINAISINDGDRLLDVQLTNTSSEIVIALESGRAIRFN---VRPMGRTAAGVRAVTLA-P
-DVVGMVCVENNTDLLVVSEKGFGKRSPLEEYRITNRGGKGVKTMNITD-KTGKLVAIKGVT-TDDLMIINRSGITIRLRVSDLRVIGRATQGVRLIKLN
-GQISSVAKVE-
>tr|A0A0M4HPY0|A0A0M4HPY0_9BACT DNA gyrase subunit A OS=Hymenobacter sp. DG25A GN=gyrA PE=3 SV=1
MEDMIADESMVITISREGYIKRTALDEYRAQGRGGVGARGAAS-NDDFTEHLFVATTHEYLLFFTELGRVFWLKVYEVPEGGKNTKGRPIQNLIEIPRED
SVRSVLNVRR--ENTFLMFCTEQGTVKKTPLEAYSR-RTAGINAISINEGDRLLDVQLTTGNSEVIVALNTGRAVRFH---VRSMGRNAAGVRGITLV-A
-DVVGMVCVSDTQELLVVSEKGYGKRSELEEYRITNRGGKGVRAMKITD-KTGALVAIKAVN-SDDLMIINRSGITIRLRVADLRTIGRATQGVRLLKIS
-GAISSVAKVE-
>tr|A0A076HVW1|A0A076HVW1_9BACT DNA gyrase subunit A OS=Hymenobacter sp. APR13 GN=gyrA PE=3 SV=1
MEDMIADESMVITISNDGYIKRTPLAEYRAQGRGGIGARGAGS-QDDFTEHLFVATTHEYLLFFTELGRVFWLKVYEVPEGGKGAKGRPIQNLIEIPRED
SVRSVLNVRR--ENTYLMFCTEQGTVKKTPLEAYSR-RTAGINAITINEGDRLLDVRLTNGNSEIVVALRSGRAVRFP---VRSMGRTAAGVRGITLA-D
-DVVGMVCVSDTQELLVVSENGYGKRSELEEYRITNRGGKGVQAMKITE-KTGALVAIKDVN-TDDLMIINKSGLTIRLRVADLRIIGRATQGVRLLKIN
-GEISSVAKVA-
>tr|I0KAM7|I0KAM7_9BACT DNA gyrase subunit A OS=Fibrella aestuarina BUZ 2 GN=gyrA PE=3 SV=1
DLSLIDDEEMIITISHEGYIKRTPLTEYRRQGRGGTGSKGATS-DGDFTEHIYSATMHNTLLIFTQKGRLYWLPVYKLQEGSRDAKGKPLPNYIQIDSDD
KVRAVINVKD--KNNFIVMCTEQGTIKKTLLEAFSN-RRTGIIAITIEEGDRLLDVVMTNGDNDLVIASRAGKAVRFH---VRPMGRTAAGVKGITLDEA
-DAVGMVCIGR---LLVLSENGYGKRSPID-YRVTNRGAKGVGTLKVTE-KVGALVGILEAS-SDDLIVINRSGVLLRTPVRNISVIGRNTQGVRVISIR
-GAISSVTTVT-
>tr|A0A098LJK1|A0A098LJK1_9BACT DNA gyrase subunit A OS=Sporocytophaga myxococcoides GN=gyrA PE=3 SV=1
IEDIIADDEMVITISHEGYIKRTPLTEYRSQSRGGVGSRGAVS-EDDFTEHLFIATMHNYLLIFTDSGKVFWQKVYGIPEGSKTSKGRPIQNLINVEKED
KVRAIINVKE--NNNFIIMVTENGTIKKTSLEAFSR-RSNGIQAITINEGDKLLNVRLTNGSNEIVIALKSGRAIRFN---VRPMGRNAAGVRGVTLAD-
-DVIGMVCLSCDNNLLVVSEKGYGKRSDIDDYRVTNRGGKGVKTLNITE-KTGKLVAIMDVS-KDELMIINKSGITIRMPVSDLRVVGRATQGVRLIKLS
-TEIASIAKIE-
>tr|A0A0H4W559|A0A0H4W559_9BACT DNA gyrase subunit A OS=Rufibacter sp. DG31D GN=gyrA PE=3 SV=1
LEDMIPDENMVITISHEGYVKRTALTEYRSQSRGGVGSRGAAG-QDDFTEHLFIASTHNYLLIFTESGRVFWLKVYEVPEGGKTTKGRAIQNLINIEKDD
KVRAVINVHK--INNYLVFCTEQGTIKKTPLEAYSR-RATGIQAITINEGDRLLDVQLTNGANDIIIALKSGRAVRFP---VRTMGRTAAGVRGITLA-P
-DVVGMVCVHNDTNLLVVSEKGFGKRSLLEEYRITNRGGKGVKTLNVTE-KTGHLVAIMGVI-TDDLMIINKSGISIRLRVADLRVIGRVSQGVRLLRLN
-GEISSVAKIE-
>tr|W8F193|W8F193_9BACT DNA gyrase subunit A OS=Hymenobacter swuensis DY53 GN=gyrA PE=3 SV=1
MEDMIADESMVITISREGYIKRTALDEYRAQGRGGVGARGAAS-QDDFTEHLFVATTHEYLLFFTEAGRVFWLKVYEVPEGGKNTKGRPIQNLIEIPRED
SVRSVLNVRR--DNTFLMFCTEQGTVKKTPLEAYSR-RTAGINAITINEGDRLLDVQLLNGNSEVVLALRSGRAVRFP---VRSMGRTAAGVRGITLSEA
-DVVGMVCLDKQDELLVVSENGYGKRSPLEEYRITNRGGKGVRAMKLTD-KTGQLVTIKTVN-TDDLMIINKSGITIRLRMSELRSIGRATQGVRLLKIS
-GEISSVAKVA-
>tr|K0P200|K0P200_9BACT DNA gyrase subunit A OS=Cardinium endosymbiont cEper1 of Encarsia pergandiella GN=gyrA PE=3 SV=1
MEDMIPDTEMVIMISNQGYIKRTPLVDYRLQGRGGVGAKGITT-KDDVTAHLFIATAHQYLLIFTEYGKIYWVKVYTIPETKKATQGKAIQNLINIAPGD
QVRSIIQVRQ--DQHYVVMSTRQGIIKKTPLRAYAI-RANGIHAIVIRAGDSLLDVQLTNGTHHIVLALASGRATQFN---VRPMGRVASGIRGITLAE-
-DVIGMACFPT---VLVVSENGYGKRSSLL-YRITKRGGKGVKTMQITE-KTGKLVAIHAVK-QDELMIMNQAGLAIRIQVSTLPLIGRATQGVRLIRLG
-EKVVSVARID-
>tr|A1ZUE0|A1ZUE0_9BACT DNA gyrase subunit A OS=Microscilla marina ATCC 23134 GN=gyrA PE=3 SV=1
DEDMIPVEEMVITISHFGYIKRTSLDEYRTQNRGGVGSRGTSK-DDDFTEHLFVASTHDYLLIFTNSGKVFWIKGYNIPEVAKTAKGRAIQNLLQMEKGD
SIRAVINVKQ--QNHYLVMCTEKGIIKKTRLEAFSR-RQNGIHAITINEDDQLLDVKLTNGENNIILAIRSGRAIHFH---VRSMGRTAAGVRGITLDD-
-NVVGMVCVARDASLLVVSETGYGKRSSIEDYRITNRGGKGVITMQITD-KTGRLVAIKEAV-TDDLILITKTGLAIRMSMSDMRVMGRATQGVRLIKLH
-DSIASVAKVD-
>tr|R5W011|R5W011_9FIRM DNA gyrase subunit A OS=Coprococcus eutactus CAG:665 GN=gyrA PE=3 SV=1
DEELIKREEIVISMTKLGYIKRMPKDTFKVQNRGGKGIKGMNI-DNDIIDEIFLTNTHNFIMFFTNMGRVYRMKGYEIPEG-RNARGVAIVNLLQLLPNE
KVTAIIPIT-F--KKYLMMATKNGIVKKTKIEAFENIRKTGLAAITLNDGDELIEVKATSGENDIFLVTTKGMCIRFN---VRDTGRTSMGVRGIRCD--
-EVIAMQLDVQGDEILFVTANGMGKRTELSEFA-QMRGGKGVKCYRITE-KTGDIVSAKAVT-DHDIMMMTNEGIMIRMHCSDIT-IGRITSGVKLMNVG
-GFVASVAKLA-
>tr|R5JY71|R5JY71_9FIRM DNA gyrase subunit A OS=Coprococcus sp. CAG:782 GN=gyrA PE=3 SV=1
DEELIEKENIVVARTHLGYIKRMQDDNFKAQKRGGKGIKGMPT-EDDYIEDIFMTTTHHYIMFFTNKGRVYRLKGYDIPESSRTARGVAIVNLLEMLP-E
KVTAIIPFK---ENKYLFMATKNGMIKKTPLIDYVN-KKSGLIAIDLKDDDDLIEVK-TDG-DDMFLITEGGMCIRFNE--VRSTGRSTMGVKGISLS--
-DVISLIMGSHGNHILFVTKNGMGKKTDINEFSSQNRGGKGLKCYKIT-E-TGNLVGAKIVNE-NEMMLITNEGIIIRFDSSDVSALGRVTSGVKLMNID
EGFVAAITKVR-
>tr|M1LMM8|M1LMM8_9PROT DNA gyrase subunit A OS=Candidatus Kinetoplastibacterium desouzaii TCC079E GN=gyrA PE=3 SV=1
TEDLIVPTDMVVTLSYNGYLKSQPLSEYRLQKRGGHGQATS-IKENDWVEHLFIANSHDFLLFFSDLGRVYWLKVWEVPQGTRGSKGKPIVNMFPLS-NE
KITVVLPVKEF--NLYVFMATANGVVKKTSLSDFSNPRKNGIIAVGLDDGDYLIGAELTNGDYDIMLFSDSGKAVRFSEKDVRSVSRSARGVRGMVLG--
KNVVSLLVSNS-KSVLIATENGFGKRTSIKHYTVHNRSTKGMIAIQNSK-RNGKVVGAVLVDLSDEIMLITTSGVLVRTRVSEIRKMGRVTQGVTLININ
SGYLSKIRKVI-
>tr|M1M424|M1M424_9PROT DNA gyrase subunit A OS=Candidatus Kinetoplastibacterium blastocrithidii TCC012E GN=gyrA PE=3 SV=1
TEDLITPTDMVVTLTHNGYLKSQPLSEYRSQKRGGHGQATV-IKENDWIDYLFIANTHDYLLFFSDLGRVYWMKVWETPQGTRGSRGKPVVNMFPLD-NE
KITVVLPVREF--DLYIFMATAKGIVKKTPLSDFSNPRRSGIIAVVLGDGDYLIGAELTDGKHDVMLFSDSGKAVRFYENDVRSMGRNSRGVRGINMD--
SKVISLLVAND-KSVLVATENGFGKRTSIKEYTRHNRGAKGMISIQTSA-RNGKMVGAILVKPDDEIMLITNGGVLVRTRVSEIRQMGRVTQGVRLMNVD
-GLLSGVRRVV-
>tr|A0A0C5WGU9|A0A0C5WGU9_9MOLU DNA gyrase subunit A OS=Mycoplasma dispar GN=gyrA PE=3 SV=1
EEDLITDEVVIISLTQNNYVKRINLDEYRLQNRGG-G--SSS--DD-ELKSLCITNTLSDLLIISSNAKIFKLRSHQIPDS-KQGKGIPFLNLLRL-D-E
N--NLIAWN--N--HWLITVSAFGNIKKTELSAFRN-P-NGKIALKMV--DYLVS---VI---DIIIASSQGLVN------LRNSGRASIGVKAINLE--
-GIIGACFTH-NDFVFSLSKNGFGKKTPV-EYR-TGRATKGLMSI---SSKAGDI-FVSTIK-GQEAIIITKRGFAIRIDL-TAPV-SR---GVKLIKLK
G-EITSVSLIK-
>tr|A0A014M1S3|A0A014M1S3_9MOLU DNA gyrase subunit A OS=Mycoplasma ovipneumoniae 14811 GN=gyrA PE=3 SV=1
EEDFIPNEKVIISLTQNNYVKRLNLEEYRLQNRGG-G--SSN--DD-ELKSVCITNTHSDLLIISSRAKIFKLRAHQIPDS-KQGKGLPFLNLVQV-D-E
N--ALIPWN--D--HWLITVSAFGYIKKTELSEFSY-P-NGKKALKLV--DYLKS---VI---NIILASSQGFVN------LRNTGRTSIGVKGIVLE--
-GIVGACYTF-NDFVFNLSKHGYGKKTPI-EYR-TGRVTKGIKGL---DEKAGDI-FVGTIG-DQEAIIITKRGFAIRIDL-SVPI-SR---GVKLIKLK
E-EISFVTLIK-
>tr|S5G0R0|S5G0R0_MYCHY DNA gyrase subunit A OS=Mycoplasma hyopneumoniae 7422 GN=gyrA PE=3 SV=1
EEDLIADEQVIISLTQNNYVKKMVLDEYRLQNRGG-G--LSN--DD-ELKSLCITNTLSDLLIISSSAKIFKLRAHQIPDS-KQGKGIPILNLIKL-N-E
S--NLIPWN--N--HWLITVSAFGNIKKTALSAFRN-T-NGKIALKLA--DYLVS---AL---NILIGSSQGFVN------LRDSGRTAIGVKGIKLE--
-GIIGACFAF-NNFIFSLSKKGFGKKTQV-EYR-TGRTTKGLMSL---AKKAGNV-FISAIK-NQEAIITTKKGFAIRIDL-MVPI-SR---GVKIITLK
G-EITAVSLIS-
>tr|A0A0A8EC11|A0A0A8EC11_MYCFL DNA gyrase subunit A OS=Mycoplasma flocculare ATCC 27399 GN=gyrA PE=3 SV=1
EEDLITDEQVIISLTQNNYVKRIPLEEYRLQNRGG-G--LSN--DD-ELKSLYITNTLSDLLIISSNAKIFKLRAHQIPDS-KQGKGIPFLNLIRL-N-E
N--SLIPWN--N--HWLITVSAFGNIKKTELNAFCN-P-KGKIALKMV--DYLVS---II---NILIASSQGLVN------LRKTGRISIGVKGISLE--
-GIIGACFTY-DDFVFSLSKNGFGKKTAV-EYR-TGRLTKGLISI---STKAGNV-FVSTIK-NQEAIITTKKGFAIRIDL-MVPI-SR---GVKLIKLK
D-EITSVSLIK-
>tr|W5UTF5|W5UTF5_9MOLU DNA gyrase subunit A OS=Mycoplasma bovoculi M165/69 GN=gyrA PE=3 SV=1
DEDLITRQDVIICLTQNNYVKRINLDEYRTQNRGG-G--SSS--DD-ELKGIWFANTHTDLLIITSKARIFKLRTHMVPDS-RNAKGTPFINLLPL-D-E
S--SLLIWN--S--HFLITISAKGIIKKTRLSEYEN-N-NGKYALKLN--DSLVK---AS---QIIIGSSSGRAN------VRASGRVAIGIKGIKLD--
-SVVGACHSQ-GSFVFTVGDLGYGKMTSV-EYR-TSRNSKGVLAL---SEKAGKC-FIGTVN-DEQAMILTKKGIAIRIDL-TIST-SR---GVKIIDIK
G-QIQSVTIIS-
>tr|A0A0R1W7R8|A0A0R1W7R8_9LACO DNA gyrase, A subunit OS=Lactobacillus concavus DSM 17758 GN=FC15_GL000510 PE=4 SV=1
DEDLIEEQDVMIVLTHNGYVKRLPATEFKVQNRGGRGIQGMGV-DDDFIEQLIYTSTHDTLLFFTNTGKVYRAKGYEIPEYGRTAKGLPIINLLGI-DGE
NVETVINVH--DDEDSLFFITRLGTVKRTTVGEFSN-RANGLRALTLRDGDELSNVL-TDG-QNILIGTHLGYAVSFNE--VRSMGRTAAGVRGIRLR--
-QVIGSAVLTPDQEILTISENGYGKRTAVSEYPIKGRGGKGIKTANIT-A-NGPLAGLTVVNS-EDLMLITTEGVLIRFPVANVSQTGRATLGVRLIKVD
G-KVATLAKVD-
>tr|A0A0R2DSS2|A0A0R2DSS2_9LACO DNA gyrase, A subunit OS=Lactobacillus floricola DSM 23037 = JCM 16512 GN=FC86_GL001228 PE=4 SV=1
DEDLIEREDVLLTLTHNGYIKRLPADEFKVQHRGGRGIKGMGV-KDDFIEKLIFTSTHDVVLFFTNTGKVYRAKGYEIPEFGRAAKGIPIINLLGI-DDE
KVQTVISVE---VDQFLFFITKNGTVKRTPISDFKN-RSKGIRSITLKEDDELNNVL-TDG-QTIFIGTHKGYAVTFSE--IRSMGRTAAGVRGIRLR--
-GVIGSDIITPDSNVLVISEKGYGKQTKATHYPIKGRGGKGIKTVNVT-E-NGPLAGIRVVNH-EDIMLITDEGVLIRFKVANVSETGRAALGVRLIKVS
N-KVATLTTVP-
>tr|A0A0F4KZW4|A0A0F4KZW4_9LACO DNA gyrase subunit A OS=Lactobacillus mellis GN=gyrA PE=3 SV=1
DEDLIEEENVLVVLTHNGYIKRLAADEFKVQNRGGRGIKGMGV-NDDFIEHLIYTSTHDDLLFFTNSGKIYHSKGYEIPEYGRSAKGIPIINLLGI-DDE
RVQAVVHIKQ-SLAKYLFFVTRLGTVKRTKLEEFQN-RKNGLRAITLKADDSLDNVL-TDG-QNILIGTHLGYAVTFKE--VRVMGRTAAGVRGIRLR--
-QVVGSDILAAQSEVLVISEQGYGKRTAASEYPIKGRGGKGIKTANIT-A-NGPLAGITTVKD-EDIMVITSNGVMIRFEVANVSQTKRATMGVRLIKIN
A-QVSTMAKVD-
>tr|A0A0R1GGU8|A0A0R1GGU8_9LACO DNA gyrase, A subunit OS=Lactobacillus bifermentans DSM 20003 GN=FC07_GL001269 PE=4 SV=1
DEDLIEEEDVVITLTHNGYIKRLPAAEFKTQNRGGRGIQGMGM-DDDFIEHLVFTSTHDMLLFFTNTGKVYRAKGYEIPEYGRTAKGIPVINLLQI-DGE
TIQTVINVS----DQYLFFTTRLGVVKRTPVSEFHN-RSNGLKAITLKENDQLIQVS-TDG-QNLIIGTHLGYAVSFAE--VRSMGRSASGVRGIRLR--
-DVVGADLLTADNKVLVISEKGYGKQTPSDQYPIKGRGGKGVKTSNVT-A-NGPLTGLVTVND-EDVMLMTDTGVAIRFHVKDVSETSRATLGVRLIRVD
N-KVATIAKVQ-
>tr|A0A0F4LX28|A0A0F4LX28_9LACO DNA gyrase subunit A OS=Lactobacillus mellifer GN=gyrA PE=3 SV=1
DEDLIAQENVLIVLTHNGYIKRLPASDFKVQNRGGRGIRGMGV-DDDFIERLIYTSTHDTLLFFTNTGKIYRSKGYEIPEYSRNAKGIPIINLLGI-DKE
RVQAVVHLPE-SEQQFLFFVTKQGTVKRTAISEFQN-RKNGLRAITLKDQDSLDNVM-TNG-QNILIGTHLGYAVTFAE--VRQMGRTAAGVRGIRLR--
-QVVGSAILKPNSEVLVISEKGYGKRTPAAEYPIKGRGGKGIKTSNIT-A-NGPLAGITTVEQ-EDIMIITDKGVLIRFAVSDVSQTGRSTLGVRLMKTN
D-IVSTMAKVE-
>tr|J3ERZ9|J3ERZ9_9LACO DNA gyrase subunit A OS=Lactobacillus coryniformis subsp. coryniformis CECT 5711 GN=gyrA PE=3 SV=1
DEDLIEEEDVVITLTHNGYIKRLPASEFKTQNRGGRGIQGMGM-DDDFIEHLVFTSTHDMLLFFTNTGKVYQAKGYEIPEYGRTAKGIPVINLLEI-DGE
RIQTVVNVA---SDNYLMFTTREGVTKRTAVSEFHN-RSNGLKAITLKESDELINVC-TDG-QNIIIGTHLGYAVSFAE--VRSMGRSATGVRGIRLR--
-GVVGSDILSPDSEVLIISEKGYGKRTPAAQYPIKGRGGKGIKTVNVS-A-NGPLAGLATVKD-EDIMLITNTGVVIRFHVRDVSQTGRATLGVRLIRVD
E-KVATMAKVA-
>tr|K9TR34|K9TR34_9CYAN DNA topoisomerase (ATP-hydrolyzing) OS=Oscillatoria acuminata PCC 6304 GN=Oscil6304_5134 PE=4 SV=1
A-TPPEPEETVLEFTRRGYVQRLSPSAYERQQQKQ-E--PIQT-AD-FVVETHVAFTDQDVLILTRDGKGFSIKVGDIPAK-RGAKKTPFVSLFPPAP--
---TQFILS--E-TLDLIFLTERGRIKRLPLSEFAN-T-RGLTAVKLK--DALAY---T----DIAIATSGGRLL------LPITSRASMPQQALRLG--
-GLVGCVALS-SEKLLLVTKLGYGKRLPV-LVR-AKPGDLGTQSM--KKT---DL-GMVAAL-DAELKLLTSSDRFLRLPV-SVRS-RK---GDRLLKLE
K-TLIYLSVSS-
>tr|K8GPT7|K8GPT7_9CYAN DNA topoisomerase (ATP-hydrolyzing) OS=Oscillatoriales cyanobacterium JSC-12 GN=OsccyDRAFT_2109 PE=4 SV=1
EEEPEQEEATVLELTQRGYARRLTLKAFQRQVKNR-E--TIPT-ED-FPVQIQRTTTGKAIIVLTRSGKAYSVRVAEVPQS--ARKGAPLITLLPPAP--
---GSFVMP--S-NQFLVILTQQGRVKRLPLEDFVD-T-RGLTALKLK--DRILQ---E----QLVVATSSGRML------LPIQSRTAQGQLVMRLG--
-KLVGCTAIS-GGVLLMVTEKGYAKRMPV-TMR-SNLGDLGANGI--TKT---DL-GIAGLR-DTEVVLVTTHDRLMRPAL-TIPM-GR---GDRILKLE
D-KVANVLVLC-
>tr|Q2JQA2|Q2JQA2_SYNJB DNA topoisomerase (ATP-hydrolyzing) OS=Synechococcus sp. (strain JA-2-3B'a(2-13)) GN=CYB_0008 PE=4 SV=1
SGEETEETHFLLQFTRKGYVRRLPLPSRRSRSNPA---------ED-VLVGLECVTLEQEILVLTAGGKAFTLPIAGIPLT-GSSRGVPLVTLLPNP---
---ATFTLD--PGKASLVVLSRQGRIKRLALAELMG-T-RGSTVLKLK--DELGW---D--GYSVVLATSGGRVL------IPLMGRAAMGSPALRLG--
-TIVGMALVP-QGILVLASRLGYLKRLSL-EIP-LERGQVGAPAF--SRG---DL-GLVGLP-HLQLDVITESEQVYSFSP-EIPL-SR---GSLLVKGE
---VRELRLFW-
>tr|K9RND4|K9RND4_SYNP3 DNA topoisomerase (ATP-hydrolyzing) OS=Synechococcus sp. (strain ATCC 27167 / PCC 6312) GN=Syn6312_0203 PE=4 SV=1
EVDTPPDLPVMVEVSQKGYGRCLTSLARNSFVIPP-A--Q----KD-YPIFQAPGQRQHTLYLVGSNGKAYSVPVAKIPLE-RNQKGQPLQTLLPDSQ--
---QFWLEP--DSYPDFVLLTHQARIKRIPATELTG-N-RALQLIKLK--DALDW---L----TLIVATSTSRIL------IPIMSRTSAGVAAFKLG--
-QIIGAIATS-TTNLLLVTAQGYAKQISV-EVR-IHLGQLGTMTF--TPH---DV-GLVAVSFVPEVGLVTNRERWQRITV-QIPC-HH---SIQIVSME
E-LVTQILPSS-
>tr|Q2JY71|Q2JY71_SYNJA DNA topoisomerase (ATP-hydrolyzing) OS=Synechococcus sp. (strain JA-3-3Ab) GN=CYA_0008 PE=4 SV=1
GGEAGEDSRFLLQLTRKGYVRRLPLPGPRSRSNPA---------ED-TLVSLECVTPEQAILVLTASGRAFTVPIEGIPLT-GSSRGVPLVTLLPNP---
---AAFPLDSGPGEASLVVLSRQGRIKRVALAELVG-S-RGAAVLKLK--DELGW---H--GYSVVLATSGGRVL------IPLMGRAAMGSPALRLG--
-TIVGMALLP-QGILVLASRSGYLKRLPL-EIP-LEQGKVGVSAF--SKG---DL-GLVGFP-HLQVDVIAESERVHSFSP-EIPL-GR---GSLLVKGE
---VRELRLFW-
>tr|A0A098TPV8|A0A098TPV8_9CHRO DNA topoisomerase (ATP-hydrolyzing) OS=Neosynechococcus sphagnicola sy1 GN=DO97_06075 PE=4 SV=1
QEYTPEPEATVVELTQRGYIRRLTPKAFQRQQRPR-S--PPE--ED-AVIQAQPADTAQELLVLTRSGKAYTLPVEEIPSR-N--RGTPLISLLPTAP--
---QTLVLP--E-GLDLLLLSHQGRIKRIPLLEFTH-T-RGLIGMKLK--DTLIH---Q----QLVLATSSGRLL------LPVMGRTTQGLAAMRLG--
-QLVGWAMVD-QVNLLLVSQQGYLQALPL-RLR-GKRGELGTQVM--ART---DL-GFLPLL-EAGVLLQTTTQRLIRLPP-SLFP-GVHYVGDRLIQAD
G-RILAVIPLI-
>tr|A0A0E3UUD3|A0A0E3UUD3_9FUSO DNA topoisomerase (ATP-hydrolyzing) OS=Sneathia amnii GN=VC03_01570 PE=3 SV=1
AEDLIKEEDVVVTITNKGYVKRITTASYKSQRRGGVGVNSINT-EDDEVSDIYTVKTLDRLLVFTDKGKAYSIKVYEIPES-KQARGRLISNIINLGENE
NVSAILNTS-S--NSQILIVTRKGIAKKMDIKLFMNINKSGIRAITLKEDDELVFTDICS-ENEVFVATKKGLAIRFE---IRAMGRSASGVRAIKLN--
-IVASACIVDKKNEVLTVTSEGYGKRTDIEEYKVQNRGGKGLKNFKITP-KTGDIVSSILVD-VKEIMLITKEGTLIRTKINEISK-SRSTSGVRIMKPK
-DVVTSVALAP-
>tr|D0GPF9|D0GPF9_9FUSO DNA gyrase subunit A OS=Leptotrichia goodfellowii F0264 GN=gyrA PE=3 SV=1
IEDLIKDEDVVVTLTEKGYVKRTSIDTYHSQRRGGIGVNATNT-EDDVIKDMYIAKNLDTLLIFTTKGKVFSMKVYEIPEG-KQARGKLISNLIKLSEDE
RVSTVIRVR-F--DKAIFFITKDGVVKKTDLTLFANINKTGIRALTLRDEDELKFAGLTSGKDEIFIATRNGISIRFC---VRVMGRTAAGVKGITLR--
-YVVAAVIINPELSVMTITEEGYGKRTALSEYKVQSRGGKGIINLKINE-KTGKIVDVKIVD-KTEIMLITSEGTLIRTKVDTVSV-GRATSGVRIMKVR
-EKVASAVKIA-
>tr|C7NEF8|C7NEF8_LEPBD DNA gyrase subunit A OS=Leptotrichia buccalis (strain ATCC 14201 / DSM 1135 / JCM 12969 / NCTC 10249 / C-1013-b) GN=gyrA PE=3 S
IEDLIKDEEVVVTLTEKGYVKRVAIDTYRSQKRGGIGVNATNT-EDDVVKDMYIAKALDTLLIFTTKGKVFSIKVYEIPEG-KQARGKLIGNIINLDDDE
KVSTIIKVR-F--NKNLFFVTRNGVVKKSELTLFDNIKKAGKRAIRLNEDDEVMFIGLTSGEDEIFAATKNGIAIRFS---VRSMGTGAAGVRGINLR--
-KIVGAAIISSDARILTITEEGYGKRTKLLEYRLTSRGGKGIINAKLNE-KTGKIVDVKIVK-DDEIMLITSEGTLIRTSVKDVSV-GRSATGVRIMKVR
-NKIASIVKIT-
>tr|U2RGL1|U2RGL1_9FUSO DNA gyrase subunit A OS=Leptotrichia sp. oral taxon 215 str. W9775 GN=gyrA PE=3 SV=1
IEDLIKDEDVVVTLTEKGYVKRVATDTYHSQRRGGVGVNATNT-EDDVIKDMYIAKNLDTLLIFTTKGKVFSMKVYEIPEG-KQARGKLISNLIKLSNDE
KVSIVIKVR-F--NRKLFFITRDGKVKKTDLTLFANINKAGIRALTLNGEDELTYIGLTSGKNEIFIATRNGVAIRFS---VRSMGRTAAGVKGIDLR--
-IVVAAAIIDPKLSVLTVTEEGYGKRTKLGEYRVQSRGGKGIINLKMNE-KTGKIVDVKIVD-ETEVMLITSEGTLIRTRVDSISV-GRSTAGVRIMKVR
-NKVASTVKIT-
>tr|A0A0G1GDQ8|A0A0G1GDQ8_9BACT DNA gyrase subunit A OS=Microgenomates (Woesebacteria) bacterium GW2011_GWB1_43_14 GN=gyrA PE=3 SV=1
EEDLVAKRNVLITLSKTGYIKMVPTNTFKSQRRGG-G--VMA--ED-EIEHIISTNTHDTILFFTNKGRVFGTNAWEIPES-RQSKGHALVNIV-NDG-E
Q--SVVA----SGSKHIIMATSQGAVKKTAIRQFDN-R-NGLIAIKLT--DKLVS---TD---HVLLVTKKGKSI------VRSMGRATTGVRGIKIDM-
-DVIAMEVFPSFKDILVIGEKGIGKRTAV-LFP-QKRGGKGVKAG---NERTGPV-TARLVT-IEQVVITSKSGQVIKLPL-NIPQ-GR---GVIMMRFA
R-MAAALTALE-
>tr|A0A0J7HLY5|A0A0J7HLY5_OENOE DNA gyrase subunit A OS=Oenococcus oeni GN=gyrA PE=3 SV=1
DEDLIDEEEVLISLTHKGYIKRLSTSEFHTQNRGGRGVKGMNT-DDDFVEQLVSTSTHDTLLFFSDQGKVYKMKGYEVPEYGRQAKGIPVINLLGL-DGE
RVQAVINVR--TSKDFLFFTTKLGTIKRTAVSEFTN-RQSGLRAINLRDDDSLISVL-TNG-QNIVIASHSGYAVSFAE--VRAMGRTASGVRGMNLR--
-KVVGADLLIPGDNVLIITEKGYGKQTAVEEYPIRGRGGKGYKTSNIS-S-NGPLAGLAVVSD-EDIMITTDSGVMIRFAAADVSITGRATLGVHVIKIE
G-KVATLVKVE-
>tr|A0A0A0M312|A0A0A0M312_9LACT DNA topoisomerase (ATP-hydrolyzing) (Fragment) OS=Oenococcus alcoholitolerans GN=Q757_00510 PE=4 SV=1
DEDLIAQEDVLISLTHQGYIKRLSTSEFHTQNRGGRGVQGMNT-NDDFVEHLVSTSTHDVLLFFSDQGKVYKMKGYEVPEYGRQAKGIPVINLLGL-DNE
HVQAVINVS--NSKDFLFFTTKFGIVKRTPVVDFSN-RQSGLRAINLRPGDSLINVL-THG-DNIIIASHRGYAVSFAE--VRQMGRSASGVKGMSLR--
-KVVGSDLLVPGNNVLVITENGYGKQTAVEEYPIRGRGGKGYKTVNVT-E-NGLVSGLTVVSN-EDIMVTTNAGVMIRFDAKDVSKTGRATLGVRVIRIE
G-KVATLTKVE-
>tr|N0ATM7|N0ATM7_9BACI DNA gyrase subunit A OS=Bacillus sp. 1NLA3E GN=gyrA PE=3 SV=1
DEDLIPKESVVITLTHNGYIKRLPVSTYRSQKRGGRGIQGMNT-EDDFVEHLITTSTHDTILFFTNKGKVYRSKGYEIPEYSRTAKGLPIINLLEVDK-E
WVNAIIPVE---DDWSLFFTTKQGVSKRSPLTSFAN-RNNGLIALNLREEDELISVR-TDG-KEIIIGTKKGMLIRFPE--VRSMGRTATGVKGINLD--
DDVVGMEVLEDNTDILIVTQKGYGKRTPAVEYRVQGRGGKGIKTCNIT-EKNGNLISMKVVT--EDVMLITTGGVLIRMDVNDISSMGRNTQGVRLIRLG
SHQVATVAKVA-
>tr|A0A077J765|A0A077J765_9BACI DNA gyrase subunit A OS=Bacillus sp. X1(2014) GN=gyrA PE=3 SV=1
DEDLIPRENIVITLTHNGYIKRLPVSTYRAQKRGGRGVQGMGT-EDDFVEHLITTSTHDTILFFTNKGKVYRSKGYDIPEFSRTAKGIPIINLLGIEK-E
WVNAIIPVE---DNWYLFFTTKDGISKRSPLSSFAH-RNNGLIALNLREGDELISVR-TDG-KDIIIGTKKGMLIRFAE--VRSMGRTATGVKGITLD--
DDVVGMEVLEENNDILIVTKNGYGKRTPASEYRIQGRGGKGIKTCHIT-EKNGELVSVRTVTE-EDLMLITTSGVLIRIDVAGISQLGRNTQGVKLITLK
SNSVATVAKVE-
>tr|K6CFJ3|K6CFJ3_9BACI DNA gyrase subunit A OS=Bacillus bataviensis LMG 21833 GN=gyrA PE=3 SV=1
DEDLIPQENIVISLTHNGYIKRLPVSTYRAQRRGGRGIQGMGT-EDDFVEHLITTSTHDTILFFTNKGKVYRSKGYEIPEFSRTAKGIPIINLLGIEK-E
WVNAIIPVE---DDWSLFFTTKEGISKRSPLTSFAN-RTNGLIALSLREGDELISVQ-TDG-KHMIIGTKNGMLIHFPE--VRSMGRTATGVKGISLD--
GDVVGMEVLEEDSDVLIVTKNGYGKRTPAAEYRIQGRGGKGIKTCHVT-EKNGNLVSMRVVTE-EDLMLITTGGVLIRIDVAGISKMGRNTQGVKLISMK
DSFVATVAKVE-
>tr|A0A0D0EJX8|A0A0D0EJX8_9BACI DNA gyrase subunit A OS=Bacillus thermoamylovorans GN=gyrA PE=3 SV=1
DEDLIPEESVIITLTRKGYIKRTPSSTYRTQKRGGRGIQGMGT-EDDFVENLITTSTHDTILFFTNKGKVYKIKGYRIPEYSRTAKGLPIINLIEIEK-E
YINAMIPVQ---NEAYLFFTTRQGISKRCPLSSFAN-RNNGLIAIHLREGDELISVR-TDG-KHIIIGTKKGMLIRFVE--VRSMGRTASGVKGITLG--
DDVIGMEILEEDQDVLVVTEKGYGKRTHASQYRIQNRGGKGIRTCNIQ-EKNGQLVAMKSVSN-EDIMIITDNGIIIRMAVSGISRIGRNAMGVKLIKLT
-DTVTAVAKVE-
>tr|A0A0M0G912|A0A0M0G912_SPOGL DNA gyrase subunit A OS=Sporosarcina globispora GN=gyrA PE=3 SV=1
DEDLIPRENIVLTLTHKGYIKRLPVSTYRAQKRGGRGIQGMGT-EDDFVEHLITTSTHDTILFFTNKGKVYRAKGYEIPEFSRTAKGIPIINLLGVDK-E
WVNAIIPVE---DDWSLFFTTKQGISKRSPLSSFAN-RNNGLIALNLREDDELISVR-TDG-KEIIIGTSHGMLIRFPE--VRSMGRTATGVKGISLS--
GDVVGMEVLDDDSQILIVTKNGYGKRTPAEEYRVQGRGGKGIKTCNIT-DKNGSLVSMKAVTE-EDVMLITTGGVLIRMAVSDISTMGRNTQGVRLIRLN
DDAVSTVAKVE-
>tr|A0A0M1NGH9|A0A0M1NGH9_9BACI DNA gyrase subunit A OS=Bacillus sp. FJAT-21352 GN=gyrA PE=3 SV=1
DEDLIPEENIIVTLTHNGYIKRLPATTYRSQKRGGRGIQGMGT-TDDFVGHLLTTSTHDTLLFFTNKGKVYRSKGYEIPEYGRTAKGLPLINLLEVDK-E
WVNAIIPVK---DDWYLFFTTRHGISKRTPLSSFAN-RNNGLIALGLREDDELISVR-TNG-KQIIIGTKSGMMIRFPE--VRTMGRTAAGVKGISLG--
NDVVGMEILEDDEEVLIVTKNGYGKRTSAEEYRIQSRGGKGIKTCNVT-EKNGELIAVKTVT-DEDLMLITAAGVLIRMEVEGISKTGRNTQGVKLIRLE
ANYVSTVAIVG-
>tr|A0A0M2SRV6|A0A0M2SRV6_9BACI DNA gyrase subunit A OS=Bacillus sp. SA2-6 GN=gyrA PE=3 SV=1
DEDLIPRENVVISLTHNGYIKRLPVSTYRAQKRGGRGIQGMGT-EDDFVEHLLTTSTHDTILFFTNKGKVYRSKGYEIPEFSRTAKGLPIINLLGIEK-E
WVNAMIHIE---DDWSLFFATKEGIVKRSPLTSFAN-RNNGLIALNLREGDELISVR-TDG-KEIIIGTKNGLMIRFPE--VRTMGRTATGVKGISLS--
DDVVGMEVLDESADILVVTKHGYGKRTPATEYRRQGRGGKGIKTCNIT-DKNGSLVTMKVVE--EDLMLITTGGVLIRIPVGGISITGRNTQGVKLISLN
ENAVATVAQVD-
>tr|A0A0M3RDH7|A0A0M3RDH7_9BACI DNA gyrase subunit A OS=Bacillus sp. FJAT-18017 GN=gyrA PE=3 SV=1
DEDLIPVETVVLTLTHNGYIKRLPASTYRAQKRGGRGIQGMGT-EDDFVEQLITTSTHNTILFFTNKGKVYKTKGYEIPEFSRTAKGIPIINLLGIEK-E
WVNAIIPVE---DDWFLFFTTKEGISKRSPLSSFAH-RNNGLIALNLREGDELISVR-TDG-KEIVIATKKGMQIRFAE--VRTMGRTATGVKGITLD--
DDVIGMEVLEDDSEVLVVTSKGYGKRTDAAEYRIQGRGGKGIKTANVI-EKNGHLVSMKTVT--EDLMLITTGGVLIRIPVDSISKVGRNTIGVKLINIK
-NSVATVAKVE-
>tr|A0A0G1QBU4|A0A0G1QBU4_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWA2_45_30 GN=gyrA PE=3 SV=1
EEDLIADEEVVVVLTRGGYIKRIKPENYRMQKRGG-G--IIE--ED-AVERLITCHTHSSLLFFTDSGKIYEVRAYEVPES-RTSKGKTIFNFL-SAG-E
H--SILAVPKKNVTGYIVMVTQNGIIKKVDSSVFEN-R-SGLIAINLK--DALDF---T---DELILATKQGQAI------VRPMGRTAAGVKAIRLKN-
-LVVGMGVVNNNQRLLVIMDQGYGKQTLI-QYK-QRRGGSGIKTA---TSKTGSV-GAYVIG-ETELIAISRKGQVIRTGL-SIPT-GR---GVRIMKLN
G-AVASITTL--
>tr|A0A0G1SLJ7|A0A0G1SLJ7_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWA2_47_21 GN=gyrA PE=3 SV=1
EEDLVPEEEVAVVVTRGGYVKRIKPDQYRMQKRGG-G--IIE--ED-VVEHLLMSHTHADVLFFTDSGKVYQVKAYEIPET-RTSKGRPVFNFL-SSQ-E
R--SVLAIP--KSKGYIVMLTRNGIIKKVEATTFEN-R-SGLIAVTLK--DTLGW---TD---DIILATKNGQSI------VRAMGRQAAGVTGIRLKK-
-SVVGMDIIRGATNLLVIMELGLGKQTPV-QYK-QRRGGSGIKTA---TQKTGRV-NARIIN-QSELIAISRKGQVIRTMI-SVPT-GR---GVRIMRMD
Q-AIASITTL--
>tr|A0A0G0ZJ81|A0A0G0ZJ81_9BACT DNA gyrase subunit A OS=Parcubacteria (Giovannonibacteria) bacterium GW2011_GWF2_42_19 GN=gyrA PE=3 SV=1
MEDLI---------TQGGYIKRVNPEEYRSQKRGG-G--IHE--ED-AVENFIAANTHDDLLFFTSKGKVLQTKMYEIPEK-RTTRGKAVINFL-PSD-E
H--AILARP--SGTSSLVMITKNGIIKKVATEHFDD-R-SGLIAIKLE--DLLRW---V---DHVILTTAKGQAI------IRQMGRQARGVGAIRLKG-
-ALVGADALRAELFLLVVMENGYGKKTNV-QYR-QRRGGSGIKTA---TSKTGSV-SAKIVS-IEEIIAISQKGQVIKTEI-QISE-GR---GVRIMRLP
K-KIASITCL--
>tr|A0A0G1NI40|A0A0G1NI40_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWA2_45_14 GN=gyrA PE=3 SV=1
QEDLIPDDPTVIIVTRGGYIKRLATSAYRVQNRGG-G--KMA--ED-IVDTFLATTTHKDLLFFTNLGRVFTTKAYEIPAT-RAARGQALPNFL-EAN-E
R--AVQALP---NEEYLVMATRQGIIKKTSREDFTN-R-SGLKAITLK--DTLEW---SD---AILLTTASGQAI------VRPMGRTAAGVHGMKLKS-
-SIVTMHVIPAKPQVLVITEQGYGKRTPL-DYR-QHRGGTGIKTA---TAKTGRV-QAAIIN-TSDLLIISEKGQVIRINS-TVSQ-SR---GVKVMKPT
Q-WAARLAGR--
>tr|D3R2Z9|D3R2Z9_MAGIU DNA gyrase subunit A OS=Mageeibacillus indolicus (strain UPII9-5) GN=gyrA PE=3 SV=1
DEELVKEEEVVITLTHFGYVKRQPVDTYQQQHRGGRGISGLQT-EDDFVETLVTTSTHDHLLFFTNTGRVFRLKGYQIPEG-RQAKGQAIVNLLQLVEGE
KVRTVITVHN--REDYLLMATARGMIKKTSLYEYANIQKNGLIAINLRPDDEVIGVKVSRLHEEVILATAGGYSLRFD---IRNTGRNTFGVSGIKLR--
-KVIGMAAV--ERHLLVISKNGYGKRSEFNEYRIQNRGGKGLITYKPTE-QTGDLAGIASIN-EDDIIIINDAGIVIRVATKEIPI-SRVTKGVRLMRTA
--QIVDLAVVQ-
>tr|A0A096A8F3|A0A096A8F3_9CORY DNA gyrase subunit A OS=Corynebacterium freneyi DNF00450 GN=gyrA PE=3 SV=1
EEDLIARENVVVTITSTGYAKRTKVDAYKSQRRGGKGVRGA-DKQDDIIRHFFVCSTHDWILFFTNKGRVYRLKAYELPEATRAARGQHVANLLEFQPGE
RIAEVLQIQ---SP-YLVLATSEGKVKKSRLEEYDS-RSAGLIAINLKE-DSLIGAR--SADDDLLLVSEHGQAIRFTD--LRPMGRATAGVLGMRFK-D
-DLLSMVVVE-GQHLLVATTGGYGKKTPLDEYTAQGRGGQGVLTLKYD-PKRGPLMGALVVSD-DEIFAVTSAGDIIRTRVNEIRA-SRATKGVRLVNLA
-GELLAIDRNV-
>tr|E5ANP4|E5ANP4_BURRH DNA gyrase subunit A OS=Burkholderia rhizoxinica (strain DSM 19002 / CIP 109453 / HKI 454) GN=gyrA PE=3 SV=1
TEDLITPQDMVVTMSHAGYIKSQPLSEYRAQKRGGRGQAIV-MKDDDWIETLFIANTHDYILCFSNRGRVYWLKVYEVPQGSRNSRGRPIVNMFPLQ-GE
KINVVLPVKEF--DKFVFLATSLGTVKKTPLEAFSRPLRKGIIAVGLDDGDFLIGAQITDGQHDVMLFSDAGKAVRFDENDVRPMGREARGVRGMQLE--
EGVIALLVAGGSQSVLTATENGYGKRTPIAEYTRHGRGTKGMIAIQTSE-RNGRVVAATLVEPDSEIMLITTAGVLIRTRVSEIREMGRATQGVTLISLD
EGKLSGLQQIA-
>tr|Q7V124|Q7V124_PROMP DNA gyrase subunit A OS=Prochlorococcus marinus subsp. pastoris (strain CCMP1986 / MED4) GN=gyrA PE=3 SV=1
DIDLIANERSVVLLTTAGYLKRMPVSEFESTSRGSRGKAGTKN-QDDEVKLFISCNDHDTLLLFSDRGVAYALPAYRVPMSSRTAKGTPSVQLLPIPREE
QITSLVSVD---NECYLLMLTKAGFIKRTPLSAFSKVRSNGLIAINLEEGDALTWVRLSTEGDSVLIGSSRGMTIHFRL--LRPLGRTARGVKSMNLK--
-DLVSMDVLSCGPWILVASAFGLGKRVPVTKFRLQKRAGMGLRAIKF--K-DDSLVGLKVLG-GEELLLVTERGVIVRTNADKISQQSRAATGVKLQRLD
-GHLSEVVLVP-
>tr|A0A0A2BAY5|A0A0A2BAY5_PROMR DNA gyrase subunit A OS=Prochlorococcus marinus str. MIT 9401 GN=gyrA PE=3 SV=1
DIDLIANDRSVVLLSEAGYLKRMPVNEFESTSRGSRGKAGTKT-GGDEVKLFISCNDHDTLLLFSDRGVAYALPAYRVPMSSRTAKGTPSVQLLPIPREE
KITSLVAVD---EDCFLLMLTKAGFIKRTSLSAFSKIRSNGLIAINLEDGDALTWVRLSKEGDSVLIGSRTGMAIHFRL--LRPLGRTARGVKSMNLR--
-DLVSMDVLTSGPWVLIASAFGLGKRVPVAQFRLQKRAGMGLRAIKY--Q-DDVLVCLKVLG-GEELLFVTEKGVIVRTNADKISQQSRAATGVKLQRLD
-GHLSEVVLVP-
>tr|A0A091BK21|A0A091BK21_9GAMM DNA gyrase subunit A OS=Arenimonas oryziterrae DSM 21050 = YC6267 GN=gyrA PE=3 SV=1
ILDLIASEDVVVTLSHSGYAKRQPTSAYRAQKRGGKGSATA-MKEEDFIDRLWVVNTHDTLLTFTSAGRVFWLKVYQLPDAGPNSRGRPIINWIPLQ-GE
KVQAVLPVREFSADQFVFFATRDGTVKKTPLSEYSRPRASGIWAINLDDGDGLVDVQLTNGERDIMLFASNGKAVRFDETEVRSMGRTATGVRGMRLVEE
PVVVSLIVVDGEGDILTASQNGFGKRTPVSEYPRKGRGTQGVIAIATSE-RNGSLVGAIQLTEQNEILLISDQGTLVRTRASEVSQVGRNTQGVTLMRVA
EGKLIAVESLD-
>tr|A0A091B0Y7|A0A091B0Y7_9GAMM DNA gyrase subunit A OS=Arenimonas malthae CC-JY-1 GN=gyrA PE=3 SV=1
VLDLIASEDVVVTLSHAGYAKRQPLTTYRAQKRGGKGSATA-VKEEDFIDRLWVVNTHDTLLTFTSTGRVFWLKVYQLPDAGPNSRGRPIINWIPLQ-GE
KVQAVLPVREFGDDHFVFFATRDGTVKKTPLSEYSRPRSTGIWAINLDEGDGLVDVQLTDGNRNVMLFASNGKAVRFDESEVRPMGRTATGVRGMRLKED
QGVVSMIVVDGDGDILTASENGFGKRTAVSEFPRKGRGTQGVIAMQTSE-RNGELVGAIQLTEQHEILLISDQGTLVRTRAAEVSQVGRNTQGVTLMRVA
EDKLIAVERVD-
>tr|C0EA09|C0EA09_9FIRM DNA gyrase subunit A OS=[Clostridium] methylpentosum DSM 5476 GN=gyrA PE=3 SV=1
IEDLIPEEDCVVTLTHYGYIKRQPTDIYKTQKRGGRGVAGMKQ-EEDFAEELFIASTHDNVLFITNRGRMYKLKCYEIPE-GRTSKGTNIVNLLPIEGDE
KVTSMIRIT-FP-DQYLVMVTKSGMIKRTVLDAYKNVRKNGLIAISLLEGDELAWVRLTNGNSQLIVATRNGMAIRFD---ARPLSRSAKGVRAIKLR--
-EVVGMARLR-GATVMTVTDRGLGRRTKIEDYRIQTRGGYGKINYHVSD-EKGHVVAVKVVD-DDDLILISNDGVIIRIRVSDVNV-SRYAGGVKVMRVQ
GDRVVTFARAD-
>tr|U2F6M2|U2F6M2_CLOS4 DNA gyrase subunit A OS=Clostridium sp. (strain ATCC 29733 / VPI C48-50) GN=gyrA PE=3 SV=1
IEDLIPQEECVLTLTHYGYIKRQPVSTYKTQRRGGRGLSGMTR-EEDFAEELFVCSSHDYVLFMTNRGRLYRQKCYQVPE-SRGSRGINIVNLLPLEENE
KVTSMIKVT-FD-DQYLIMVTRQGVIKRTALSAFYTNRKGGLICITLDEGDELAWCRLTGGQNQLIVATQMGKAIRFD---VRPLGRSARGVKAIALE--
-QVIGMARVR-GATLVTVTEKGLGRRTDLSEYRLQARGGKGITNYKQVE-QNGQVCNIKVVD-EDDLILIASNGVIIRISVADISV-SRYAQGVRVMRVP
EGRVVTMARTA-
>tr|A0A0E2ZBY4|A0A0E2ZBY4_9GAMM DNA gyrase subunit A OS=Francisella philomiragia GN=gyrA PE=3 SV=1
REDLITEEDMVVTLSMDGYVKTQPLSMYNAQKRGGVGSATK-TKEEDSIFKLMLASTHDTMLCFSSLGRVYWSKVYDFPVASRISKGRPINNILPLD-NE
RITALMPISEFTEGWYVFMSTKLGRVKKVDLSEFARPRSTGKIAIGLNDGDELSYVALTDGNKQIMMFSDAGKAIRFDESDVRAMGRSAAGVTGMRLHD-
-QIVSVIVTNPEGVVLAATENGYGKRTAVSEYRKTKRASQGVIAISTSE-RNGKVVVAVLVDNDEDIVMITDNGTLVRTSSDQVRECGRSAQGVRLINLR
NNKLISLKVVK-
>tr|K9WN02|K9WN02_9CYAN DNA topoisomerase (ATP-hydrolyzing) OS=Microcoleus sp. PCC 7113 GN=Mic7113_5537 PE=4 SV=1
E-LVVEEEETVLEFTHHGCVLRQR---------PT-T--KTQS-ND-FVVETLTTITQAELVVITSAGKAYPVKVRDIPPA-GLQAGTPLVKLLPEVS--
---AYYILP--D-TLSLILLTQQGRIKRLPASELTN-T-RGTTPIKLK--DQLQY---Q----QLALATSNGRIL------LPLMGRSAQGNQALRLQ--
-RLVGCVTLS-KENLLLVSEQGYGKRVPV-LFR-VNRGELGTQAL--KAT---DL-AMTKAL-KSEVMLVTSAERTVSLQM-SVKI-GK---GDRIAKLK
E-KILSVSVLS-
>tr|B4W4B2|B4W4B2_9CYAN DNA topoisomerase (ATP-hydrolyzing) OS=Coleofasciculus chthonoplastes PCC 7420 GN=MC7420_8225 PE=4 SV=1
NLIETEAEQTVLEFTYQGHVQRLRSAPDPKS--------P----ND-FVIQTQQTTTASEFATLTSGGKAYPLKVQDIPPA-GR-QGIPVTRLLPDA---
-TVAHFRPH--TESVSLILLTQQGRVKRLPATELLN-T-RGLTTVKLK--DVLAY---Q----DLIIATSNGRLL------LPIMGRTAQGNQ-LRLR--
-RLVGCVAIAP--NLLLVSEQGYGKRIGL-VVR-IKRGDLGTQAL--KST---DL-GVINAST---AVLLTSDERVMTVSL-SVKL-GK---GDRLVKLK
N-TIIDVTTIL-
>tr|F4Y2G5|F4Y2G5_9CYAN DNA topoisomerase (ATP-hydrolyzing) OS=Moorea producens 3L GN=LYNGBM3L_69100 PE=4 SV=1
PNAPTEPEQTLLEFTSHGYVQRQSATTQPKL--------K----ED-FVVQAQLLLTTQELMVITGSGKAYPVKIRDIPPA-GR-QGIPLVKLLPNS---
-TVAHFRVP--LENFTLVLLTHQGKIKRVSVSELTK-T-RGMLLTKFR--DQLQY---T----QVVVATSNGRLL------LPIMGRSAQGNQ-LRLK--
-KLVGCVVLGE--NLLLVSEQGYGKRLPV-AIR-ANRGDLGTQAL--KAK---DL-SMVRDSD---VMVVT-SLGGKRLAM-SVPI-GK---GDRIAQLK
E-KIISVTPVI-
>tr|K9Y7M6|K9Y7M6_HALP7 DNA topoisomerase (ATP-hydrolyzing) OS=Halothece sp. (strain PCC 7418) GN=PCC7418_0711 PE=4 SV=1
KPPTAPPDSAILEITRQGSVYWTPEAT-------------NEK-KD-FVVFRSPLHTEQSLITITDAGKAYSLKTESIPPY-QKQ-NTSLNKVLQGIE--
---SHLPLP-----KDVILLTQQGRIKRLATADIAS-G-RGLSLVKLK--DRVVD---T----NFLLATSGGRIL------IPQMGRTAQGNLATRLR--
-QAVGCVSLS-EASILLVSQLGYAKRIPV-TIR-GSRNDIGTQCL--TIS---DV-GMVAAE-TKVVKLLSDQGRVFSLTM-DVAI-GK---GDRAVNLK
E-TITQVIPIV-
>tr|K9YVW8|K9YVW8_DACSA DNA topoisomerase (ATP-hydrolyzing) OS=Dactylococcopsis salina PCC 8305 GN=Dacsa_1547 PE=4 SV=1
TSQATPPDSALIEITQQGKVYWCEEAT-------------TEK-KD-FVVFRSKIPQEQPLITITDFGKAYSLKTDGITPS-AKQ-KTSLNKVLQGME--
---HHLPLP-----QDVILLTQQGRIKRLSASEVAS-G-RGLSLIRLK--DRLAD---A----NLLLATSSGRIL------LPVTSRTAQGNLATRLW--
-SPVGCVSLQ-DEAVLVISQQGYAKRLSV-TIR-GSRGDIGTQCL--IRF---DV-GMIEAR-NDKVKVLTNQKRVLTLNL-DIPF-GK---GDRVITLK
E-AIAEIISII-
>tr|L8MA95|L8MA95_9CYAN DNA topoisomerase (ATP-hydrolyzing) OS=Xenococcus sp. PCC 7305 GN=Xen7305DRAFT_00048880 PE=4 SV=1
VLKITKEAQATINFTHEGHIYWQNPNDQ-----T-----S----ED-FVVRQEIIGDRETIIFITDSGKAYPVAIEEIPHL-EN-QTQTTIGLLSQAA-N
-KTEHFFLD--EK-RDLILLTTKGVIKRLAIAELNN-G-RGFVLIKLK--DHLQY---Q----EIAIATSTGRIL------IPTMGRNAQGNQ-IKLR--
-EIVGCANVTD--NILLVTRLGYSKQFPV-TAR-CKRGDLGTYII--AKQ---DL-GILLAQE---VILTTNTGKQLVQEL-KIEI-GK---PQKIAKLD
K-AIVNIYLKP-
>tr|K9VW60|K9VW60_9CYAN DNA topoisomerase (ATP-hydrolyzing) OS=Crinalium epipsammum PCC 9333 GN=Cri9333_0804 PE=4 SV=1
N-TEPPETEVVLEFTQKGYVRRLPKNGG-----KS------AG-ND-FVINTNIIGSQAELVVLTSSGKAYPVKVRDIPPS-SNSRGTPLITLLPAAS--
---KHFFLS--K-DANLVLVTQKGQIKRLQASELTN-T-RGLTLIKLK--DKLSF---K----QVVLATSGGRLL------LPVMGRTAQGLQALRLG--
-ALVSAMSVS-NDNLLLVSQLGYGKRLPI-ALR-ANRADIGTQSF--TKQ---DI-GVIIVQ-ASEVVLVTSTQRYLRLNA-QVPL-GK---GDRIIQLN
D-KIISLAISN-
>tr|D8FUK0|D8FUK0_9CYAN DNA topoisomerase (ATP-hydrolyzing) OS=[Oscillatoria] sp. PCC 6506 GN=OSCI_500003 PE=4 SV=1
VST-EPSEATVLEFTHKQYVRRLASAE--SSRGKN-D--S-QS-SD-FSVNTIQARTNENLAILTRTGKAYPLKISDIPTG-NRDRGTPIISLLSPSV-A
PGNGMFVLS--D-ATDLVTLTQQGKIKRLPLSELSD-T-RGVTAVKLK--DELRY---K----QVVLATSGGRLL------LPPMGRAAQGSQATRLR--
-QLVGCITLA-DGSLLLVSELGWAKRMPV-SVR-TGRGEIGTQAF--APK---DL-GIVAAL-RKELKLLTNNGRLLRVGV-KIAF-GK---GDRAVNLN
S-KIVKVVSC--
>tr|F2KZE1|F2KZE1_PREDF DNA gyrase subunit A OS=Prevotella denticola (strain F0289) GN=gyrA PE=3 SV=1
AEDFYPNDPVVITISHLGYIKRTPLADFKEQARGGVGSKGART-EKDFTEYIYPATMHQTMLFFTRKGRCYWMKCYDIPEGDKNAKGRAIQNMLSLEAGD
AVNAFLRIRD--DSHFVVFATKQGIVKKTSLRAYSR-RTNGVIAININEGDEVVDVRLTNGKNELIMADRNGRACRFD---IRTMGRVSTGVRGMRLD-G
-DVVGMIVVNDNETVMVVSEEGYGKRSQVE-YRLTNRGGKGVKTLNITE-KTGKLVAIKNVT-ANDLMIINKSGIVIRMSVAECRVMGRATQGVRLINLA
KNVIASVCKVM-
>tr|I4Z6J8|I4Z6J8_9BACT DNA gyrase subunit A OS=Prevotella bivia DSM 20514 GN=gyrA PE=3 SV=1
AEDFYPNDPVVITISHLGYIKRTPLTDFKEQARGGVGSKGART-EKDFTEYIYPATMHQTMLFFTKNGRCYWMKCYDIPEGDKNSKGRAIQNMLSLEPGD
SVNAFLRIRD--DKHYVVFVTKKGLVKKTSLRAYSR-RTNGVIAININESDEVVDVRLTNGNDELIIANRNGRACRFH---VRTMGRVSTGVRGMKLD-C
-DVIGMVVVNDNETVMVVSEEGYGKRSLVD-YRLTNRGGKGVKTLNITE-KTGKLVAIKTVT-DNDLMIINKSGIVIRMAVAKCRVMGRATQGVRLINLS
KNTIASVCKVM-
>tr|F8E094|F8E094_CORRG DNA gyrase subunit A OS=Corynebacterium resistens (strain DSM 45100 / JCM 12819 / GTC 2026) GN=gyrA PE=3 SV=1
EEDLIARENVVVTITSTGYAKRTKVDSYRSQRRGGKGVRGA-EKQDDVVRHFFVCSTHDTILFFTNFGRVYRLRAFELPEASRTARGQHVANLLEFQPGE
QIAQVIQIQ---AP-YLVLATSHGRVKKSRLTDYDS-RSGGLIAINLNE-DRLVGAQ--TAEDDLLLVSEEGQAMRFTE--LRPMGRATAGVKGMRFR-D
-DLLALTVVQ-DAYLFVATSGGYGKRTKMEEYPAKGRGGLGVVTFKYD-KKRGKLIGALTVQD-DEILAITSAGGVIRTEVNQIRH-SRATMGVRLVDLG
-DELVAVDRNI-
>tr|X5DMF2|X5DMF2_9CORY DNA gyrase subunit A OS=Corynebacterium glyciniphilum AJ 3170 GN=gyrA PE=3 SV=1
EEDLIARENVVVTITSTGYAKRTKVDSYRSQRRGGKGVRGA-EKQDDIVRHFFVCSTHDIIMFFTNYGRVYRLKAYELPEATRTARGQHVANLLEFQPGE
QIAQVIQIQ---AP-YLVLATQQGRVKKSHLTDYDT-RSGGLIAINLNE-DKLIGAR--TGEDDLLLVSEEGQALRFTD--LRPMGRATAGVKGMRFK-D
-DLLALTVAD-NSYLLVATSGGYGKRTAVEEYPVKGRGTLGVMTFKYD-PKRGKLIGAVTVGD-DEVFAITSAGGVIRTPVKQIRS-SRATMGVRLVDLA
-GELLAVDRNV-
>tr|S4XG88|S4XG88_9CORY DNA gyrase subunit A OS=Corynebacterium terpenotabidum Y-11 GN=gyrA PE=3 SV=1
EEDLIARENVVVTITSTGYAKRTKVDSYRSQRRGGKGVRGA-EKQDDIVRHFFVCSTHDIIMFLTNFGRVYRLKAFELPEASRTARGQHVANLLEFQPGE
QIAEIIQIQ---AP-YLVLATQQGRVKKSRLTDYDT-RSGGLIAINLNE-DKLIGAQ--TDDDDLLLVSEEGQALRFTD--LRPMGRATAGVKGMRFR-D
-DLLSLTVVR-DSCLLVATSGGYGKRTPMEEYPVKGRGTMGVVTFKYD-PKRGKLIGAVAVGE-DEIFAVTSAGVIIRTGVGQIRK-SRATMGVRLVDLE
-GELLAIDRNV-
>tr|B1VDY1|B1VDY1_CORU7 DNA gyrase subunit A OS=Corynebacterium urealyticum (strain ATCC 43042 / DSM 7109) GN=gyrA PE=3 SV=1
EEDLIARENVVVTITSTGYAKRTKVDSYRNQRRGGKGVRGA-ERQDDVVRHFFVCSTHDTVLFFTNMGRMYRLKTYELPEATRTARGQHVANLLEFQPGE
QIAQVIQIQ---AP-YLVLATAQGRVKKSRLTDYAT-RSSGLIAINLNE-DKLIGAQ--SAEDDLLLVSEEGQAMRFTE--LRPMGRATAGVYGMRFR-E
-DLLAMTVVQ-DSALFVATSGGYGKRTPMEEYPAKGRGGLGVVAFKYQ-KSRGKLIGALTVTD-DEILAMTSAGGVIRTEVNQIRE-GRSTMGVRLVDLD
-GELVAVDRNV-
>tr|A0A0B6TS99|A0A0B6TS99_9CORY DNA gyrase subunit A OS=Corynebacterium marinum DSM 44953 GN=gyrA PE=3 SV=1
EEDLIARENVVVTITSTGYAKRTKVDAYKSQKRGGKGVRGA-EKQDDIVRHFFVSSTHDWILFFTNFGRVYRLKAYELPEASRTARGQHVANLLEFQPEE
RIAQVIQIQ---AP-YLVLATAQGRVKKSRLTDYES-RSAGLIAINLNE-DRLIGAA--NEGDDILLVSQFGQSIRFTE--LRPMGRATAGVKGMRFR-D
-DLLAMSVVR-GEFLLVATSGGYGKRTAINEYSTQGRGGLGVVTFKYT-PKRGRLIGAVAVDD-DEIFAITSAGGVIRTVVNQIRP-SRATMGVRLVNLE
-GELLAIDKNV-
>tr|C4LGC6|C4LGC6_CORK4 DNA gyrase subunit A OS=Corynebacterium kroppenstedtii (strain DSM 44385 / CCUG 35717) GN=gyrA PE=3 SV=1
EEDLIARENVVATITSTGYAKRTKVDLYRNQKRGGKGVRGA-EKQDDVVRHFFVTSTHDWILFFTNFGRVYRLKAYELPEASRTARGQHVANLLEFQPGE
HIAQVIQLQ---AP-YLVLATKQGRVKKSKLTDYDS-RSGGLIAINLNE-DSLIGAQ--SANDDLLLVSEEGQAMRFTD--LRPMGRATAGVKGMRFR-E
-DLLALTVVR-DSYLMVATSGGYAKRTKMEEYPAKGRGGLGVATFKYN-KKRGKLIGALVVDD-DEIFCITTDGSVVRSNVKDIRP-SRQTMGVRLVHLD
-GELLAIDRNV-
>tr|A0A098BYL7|A0A098BYL7_9PORP DNA gyrase subunit A OS=Porphyromonadaceae bacterium ING2-E5B GN=gyrA PE=3 SV=1
MEDFYSDDEMIITISHLGYIKRTPLAEFHTQNRGGVGAKGTDT-EEDFVEYIYPATMHNYMLLFTKKGKCYWLHVYEIPEGTKNSKGRAIQNLLNIDPDD
SVTAFVRVDT--NSNYLIFCTEQGIIKKTQLEAYSR-RQNGVNAITIKEGDQVISVRLTNGNQHIILANRNGRAIRFD---VRPMGRTATGVKGMTLDDG
-DVIGMICMSPENSILVVSEQGYGKRTKLNIYRITRRGGKGVKTLNITE-KTGKLVAIKSVT-DNDLMIINKSGITIRMNISDIRIMGRATQGVRLINLE
RNQIASVCKVD-
>tr|F8X3I8|F8X3I8_9PORP DNA gyrase subunit A OS=Dysgonomonas mossii DSM 22836 GN=gyrA PE=3 SV=1
PEDFYANDEMIITVSHFGYIKRTPLTEFRAQNRGGVGAKGSET-DADFIEHIYPASMHNYILLFTQKGKCFWLRVFDIPEGSKNSKGRAIQNLLNIESDD
KVTAFIRVRS--NSHYLVFCTQAGVIKKTRLEAYSR-RQNGVNAITIREDDRVIEVLMTDGDSEILIANRNGRAIRFH---VREMGRTATGVRGMRIDDG
-DVIGMLAMSKTHTIMVVSEQGYGKRTNLNVYRITSRGGKGVKTLNITD-KTGKLVSINSVT-DNDLMIINKSGITIRLKVSDIRTMGRATQGVRLINLG
RNEIASVCKVD-
>tr|M1NNI1|M1NNI1_9CORY DNA gyrase subunit A OS=Corynebacterium halotolerans YIM 70093 = DSM 44683 GN=gyrA PE=3 SV=1
EEDLIARENVVVTITSTGYAKRTKVDAYKSQKRGGKGVRGA-ERQEDVVRHFFISSTHDWILFFTNFGRVYRLKAYELPEASRTARGQHVANLLEFQPEE
RIAQVIQIQ---AP-YLVLATAHGRVKKSRLTDYES-RSAGLIAINLND-DRLIGAA--SEDDDLLLVSEEGQAVRFTD--LRPMGRATAGVKGMRFR-E
-DLLAMSVVR-GAYLLVATSGGYGKRTGMEEYTAQARGGLGVMTFKYT-PKRGKLIGALAVDD-DQIFAITSAGGVIRTEVNQIRP-SRATMGVRLVNLE
-DQLLAIDKNV-
>tr|A0A077KQJ7|A0A077KQJ7_9FLAO DNA gyrase subunit A OS=Chryseobacterium sp. StRB126 GN=gyrA PE=3 SV=1
IEDIIPNESVVLTISHAGYVKRTSLSEYKIQSRGGVGNKAATT-DSDFLEYIVSATNHQYMLFFTEKGRCYWLRVFEIPEGSKTAKGRAVQNLINIEPDD
KIKAYIRTNK--NQMSVVMVTKNGTIKKTSLEAYSR-RVNGVNAIEIRDNDQLLGAYLTNGTSQIMIATKNGKCIRFP---VREVGRGSIGVRGIAME--
-DAIGMIVVND--TVLVVSEKGYGKRTAVE-YRITNRGGKGVITLNITE-KTGNLIAIQNVT-EDGLMIINKSGVAIRMGMDEMRVMGRNTQGVKLINLK
-NEIAAIAKVE-
>tr|E4T907|E4T907_RIEAD DNA gyrase subunit A OS=Riemerella anatipestifer (strain ATCC 11845 / DSM 15868 / JCM 9532 / NCTC 11014) GN=gyrA PE=3 SV=1
IEDFIPNEEVVLTISHAGYIKRTLLSEYKTQSRGGVGNRAAST-DEDFLEYIVSATNHQYMLFFTEKGKCYWLRVFEIPEGSKTAKGRAIQNLINIEPDD
KIKAYIRTNK--KQMYVVMITKNGTIKKTSLEAYSR-RTNGIHAIEIREDDQLLGARLTNGNSEIMIATKNGKCIRFP---ARAVGRTSIGVRGISLE--
-DVIGMIVVND--TVLVVSEKGYGKRTAVE-YRVTNRGGKGVITLNITE-KTGQLIAIQSVV-GNDLMIINKSGVAIRMSVDNMRVMGRNTQGVRLINLK
-NEIAAVAKVE-
>tr|R9CIL0|R9CIL0_ELIME DNA gyrase subunit A OS=Elizabethkingia meningoseptica ATCC 13253 = NBRC 12535 GN=gyrA PE=3 SV=1
IEDFIPNEQVVLTISHAGYIKRTPVNEYKVQSRGGVGNRGATT-DADFLEYIVAATNHQYMLFFTEKGKCYWLRVFEIPEGSKTSKGRAIQNLINIEPDD
KIKAYLRTDK--EKMSVVMITKNGTIKKTSLEAYSR-RVNGINAIEIREDDQLLGARLTDGTSEIMIATKNGKCIRFP---VRSVGRTSIGVKGITME--
-DVIGMIAVND--SVLVVSEKGYGKRTAVE-YRITNRGGKGVITLNITD-KTGQLIAINNVT-EHDLMIINKSGVAIRMSVEEMRVMGRNTQGVRLINLK
-NEIAAIAKIE-
>tr|A0A0P0E2T2|A0A0P0E2T2_9MICO DNA gyrase subunit A OS=Microbacterium sp. No. 7 GN=AOA12_00040 PE=4 SV=1
MEDLIPQEEMVVTVTRDGYIKRTRSDNYRSQHRGGKGVKGA-QRADDVVEHFFVTTTHHWLLFFTNKGRVYRAKAYEVPEAGRDAKGQHVANLLALQPGE
QIAQMLDIR---AT-YLVLATRDGKIKKTALSEYDT-RQGGIIAIKLRGGDELVSAM--DEDDDILLISRHGMSLRFTD--LRPMGRSTEGVKAMEFR-G
-DLLSASVARDDEFVFVVTEGGYAKRTSVDQYRRQGRGGLGIKVAKLN-E-RGDLAGGLIVGD-DEVLVVLASGKVVRSAVAEVPA-GRDTMGVVFARPD
-DRIIAIARNG-
>tr|A0A031FVR0|A0A031FVR0_9MICO DNA gyrase subunit A OS=Microbacterium oleivorans GN=gyrA PE=3 SV=1
MEDLIPEEEIVVTVTRNGYVKRTRSDNYRSQHRGGKGVKGA-QRADDVVEHFFVSTTHHWLLFFTTKGRVYRAKGYELPEAGRDAKGQHVANLLALQPGE
DVAQILDIR---AE-YLVLATRDGKIKKTALTEYDT-RQGGIIAIRLRGGDELVSAM--DSTDDLLLVSRLGMSLRFTD--LRPMGRSTEGVKGMSFR-G
-DLLSASVVRDDSFVFVVTEGGFAKRTSVDQYRVQGRGGLGIKVAKLH-D-RGELAGGLIVND-DEVLVVLASGKVVRSAVAEVPA-GRDTMGVVFARPD
-DRILAIARNG-
>tr|W0ZAK1|W0ZAK1_9MICO DNA gyrase subunit A OS=Microbacterium sp. C448 GN=gyrA PE=3 SV=1
MEDLIPEEEMVVTVTRDGYIKRTRSDNYRAQHRGGKGVKGA-QRADDVVEHFFVTTTHHWLLFFTNRGRVYRAKAYELPEAGRDAKGQHVANLLALQPGE
EIAQVLDIR---AT-HLVLATRGGLVKKTRLTEYDT-RQGGIIAISLREGDELESAL--EADDDILLISRHGMSLRFTD--LRPMGRSTAGVKGMSFR-N
-DLLSASVAPQGHYVFVVTDGGYAKRTAVAEYRGQSRGGLGIKVAKLS-D-RGVLAGGLIVGD-DEVLVVLASGKVVRSSVAEVPA-GRNTMGVVFARPG
-DRIIAIARNG-
>tr|F6IUI0|F6IUI0_LACPE DNA gyrase subunit A OS=Lactobacillus pentosus MP-10 GN=gyrA PE=3 SV=1
DEDLIEEEEVAVTLTHNGYIKRLPTTEFKSQHRGGRGIQGMDV-DDDFIEHLLTTSTHDVLLFFTNAGKVYRMKAYEIPEYGRTAKGIPVINLLGV-NGE
KIQAVVNVT--ASDNYLFFTTVNGVVKRTPVQEFAN-RSNGLKAITLKDDDELIGVT-TDG-QNVIIGTHDGYAVSFDE--VRSMGRTASGVRGIRLR--
-DVIGFDVLKPDSNVFIITEKGYGKQTPAADYPIKGRGGKGIKTANVT-D-NGHLAGLTTVDQ-EDIMVMTNQGVMIRFNIATVSQTGRATLGVRLIRLD
D-KVATMAKVD-
>tr|A0A0H4R1N4|A0A0H4R1N4_9LACO DNA gyrase subunit A OS=Lactobacillus ginsenosidimutans GN=gyrA PE=3 SV=1
DEDLIEEENILIVLTHNGYIKRLSADEFRVQNRGGRGIQGMGV-DDDFIEQLIYASTHDRLLFFTNTGKVYRTKGYEVPEYGRTAKGIPVINLLNI-EGE
KIQTIINVG--RDNSFLFFVTKYGTVKRTAVNDFAN-RHSGLRAIALRDEDELNNVF-TDG-KVIFIGTHKGYAVTFSE--VRPMGRTASGVRGIKLR--
-EVVGSSILSSDQEVLTISENGYGKRTAATEYPVKGRGGKGIKTANVT-E-NGPIAGVAAVSD-EDIMLVTNTGVMIRFDVENVSQTGRATLGVRLIKVD
K-FVSTMALIA-
>tr|A0A0R1QSA4|A0A0R1QSA4_9LACO DNA gyrase subunit A OS=Lactobacillus mindensis DSM 14500 GN=FD29_GL000017 PE=4 SV=1
DEDLIEEENILIVLTHNGYIKRLSADEFRVQNRGGRGVQGMGI-DDDFIEQMIYTSTHDRLLFFTNAGKVYRIKGYEVPEYGRTAKGIPVINLLNI-EGE
KIETVINVDR--DSSFLFFVTKYGTVKRTPVNDFAN-RHSGLRAITLKDEDELNNVF-TDG-KVIIIGTHKGYAVTFSE--VRPMGRTAAGVRGIKLR--
-EVIGSSIAKEGQEILTISEKGYGKRTAVEEYPVKGRGGKGIKTANVT-E-NGPIAGLSVVDT-EDIMLITDKGVMIRFEVQSVSQTGRATLGVRLIKVD
D-IVSTMTKVA-
>tr|A0A0R1IXY5|A0A0R1IXY5_9LACO DNA gyrase subunit A OS=Lactobacillus tucceti DSM 20183 GN=FC72_GL000699 PE=4 SV=1
DEDLIEEENILIVLTHNGYIKRLSADEFRVQNRGGRGIQGMGI-DDDFIEHMIYASTHDRMLFFTNTGKVYRTKGYEVPEYGRTAKGIPVINLLNI-EGE
KIQTVINVG--KENSFLFFVTKYGTVKRTPVTDFAN-RHSGLRSITLKDGDELTNVF-TNG-KVIFIGTHKGYAVTFRE--VRPMGRTAAGVRGIKLR--
-EVVGSSIVEPGQEVLTISEKGYGKRTKVEEYPIKGRGGKGIKTANVT-E-NGPIAGVTSVND-EDIMLITDKGVMIRFDVESVSQTGRATLGVRLIKVD
N-IVSTMAKIE-
>tr|C3JD53|C3JD53_POREA DNA gyrase subunit A OS=Porphyromonas endodontalis (strain ATCC 35406 / BCRC 14492 / JCM 8526 / HG 370) GN=gyrA PE=3 SV=1
PEDFYADDEMIITISHLGYIKRTPLRDFRSQARGGVGSKGSTT-EEDFIEYIYSASMHATLLLFTTKGRCFWLPVYKIPEGAKSTKGRAIQNILNIEADD
RITACIRIKQ--ASHYLVFATLQGMIKKTPLEAYSN-RSKGVFAIKLNEGDSVVSVRLTNGKTEILLANKGGRAIRFP---VRSMGRVTTGVRGMILDGG
-DIVGMVALK-KETILVVSECGYGKRTTLDSYRITNRGGKGVKTMQITE-KTGSLVDFRSVT-ELDLMIINRSGVAIRMPMSSINVIGRATQGVKLINLS
RGEIASVCIVA-
>tr|A0A0A2G4R1|A0A0A2G4R1_9PORP DNA gyrase subunit A OS=Porphyromonas gingivicanis GN=gyrA PE=3 SV=1
PEDFYADDEMIITISHLGYIKRTPLSEFRSQARGGIGSKGSTT-EEDFIEYIYSASMHATLLLFTTKGRCHWLHVYEIPEGAKNTKGRAIQNILDIDPDD
RITACIRIKE--NSHYLIFATQQGLVKKTLLEAYSR-RSKGVNAINLNEGDRVVTVRLTNGNAEILLANRNGRAIRFH---VRAMGRIATGVRGITLDD-
-DVVGMVALK-EESLLVVSEGGYGKRSLLDTYRTTNRGGKGVKTMQITE-KTGRLVDFRAVT-ELDLMIINKSGVVIRMPMESISTIGRATQGVRLINLA
REEIASVCSVA-
>tr|R6M8J9|R6M8J9_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:302 GN=gyrA PE=3 SV=1
DESLIPEDMIVVTLTKKGYIKRLSASTYKTQHRGGVGIKGMST-DEDFVEQILNCSTHDYVLFFTNMGKVYRVKGYKIPES-RQSKGLPIINLLNLEQGE
YVTALLNGS---EDKYLVFATKSGLIKRTDLAEFYNIRTNGKRFITLRDDDELISVKGTTGDNDILMASSNGRMVRFN---IRVMGRGASGVRGINL---
-FLVGMEVV--DEDVLVISEYGYGKKTPIEEYRITNRGGKGVKTINITE-KNGSIVSFKTVT-DKDLIIITDTGMIIRLAVDKISR-SRVTQGVRLINLK
-DKVSGTAIVD-
>tr|R5YQB0|R5YQB0_9MOLU DNA gyrase subunit A OS=Mycoplasma sp. CAG:611 GN=gyrA PE=3 SV=1
DESLIPVENIMISLTEKGYIKRLAVNTYRTQNRGGVGIKGMTT-EEDNVNKLITSSTHDDILFFSNYGKVYRVRGYEIPLS-RQSKGLPIINLIPIEKEE
KITSIISIDN--DEKNLVFVTKYGLVKRTNIKEFESIRNNGKIAITLKEDDELINVNLTDGTNEIIIAANNGRMVRFN---VRLMGRTASGVKGIEL---
-YVIGAEVA--SKLILVITEKGYGKKTETDEYRLTHRGGKGVKALNITD-KNGLIVAFKSVV-DEDIIITTNSGIVIRLDVNKIST-KRNTQGVRLISLK
-NIVTNVTVTE-
>tr|R5IU97|R5IU97_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:1193 GN=gyrA PE=3 SV=1
DESLIPVDNIMITLTNKGYIKRLPIDTYKLQNKGGVGIKGMST-EEDFVEHMLAMTTHDYLMFFTNKGKVYRMKGYEVPES-RQAKGLPIINLLPIEKGE
KVSSMFMIS---ECKYLVFATKKGLIKRCNINEFESIRTNGKIAITLKEDDELISVSKTDGSKFIALASSNGRLVRFD---IRIMGRSASGVRGIDL---
-YCIDANIA--DKEVLVVTENGYGKRTIINEYRTTHRGSKGVKTLNSTE-KTGNIVAFKVVN-DEDLMIITNSGMVIRIPISQISV-SRVTQGVRLITLK
-NKVTSVFNIT-
>tr|R7HJM3|R7HJM3_9FIRM DNA gyrase subunit A OS=Firmicutes bacterium CAG:321 GN=gyrA PE=3 SV=1
DESLIPVENVVITLTNKGYIKRLPADTYKTQNRGGMGVKGMAT-EEDFVEHLINATSHDYILMFTNMGKVYRIKGYEIPE-SRQSKGLPIINLLSLDKDE
KVTSLLKIS---EYKCLVFATKNGLIKRTDISEFDSIRTNGKKFITLKDNDELVSVKKTTGNDEILMASSNGRMVRFN---VRIMGRSASGVRGINLD--
-ILVGMEI-V-NDYVLVITEKGYGKKTPVDEYRITNRGGKGVKTVNITE-KNGSIVSFKTVD-SKDIMIITDSGIIIRLAVDKIST-SRVTQGVKLINLK
EDIVSSTSIVD-
>tr|R7HF78|R7HF78_9MOLU DNA gyrase subunit A OS=Mycoplasma sp. CAG:472 GN=gyrA PE=3 SV=1
DESLISEENIMVVLTKKGYIKRTKPDVFRTQNRGGMGVKGITT-DEDFVDQACNLSTHDHILFFTNKGKVYRMKGYEVPES-RTSKGLPIINLLPLLKDE
FVTSIVSIS---TKDYLFFATKKGIVKKTSINEFENIRTSGKICISLKDNDELIGVRLASNNDLILLGSSSGKLVKFN---VRTMGRTASGVRGINL---
-ECICLETV--SNTILIVTELGYGKQTLVSEYRQTKRGSKGVKALNVTE-KNGNLVSVKVSD-NKELILMTNSGITIKMPISQIST-GRATQGTRLIHLK
-NKVTAISIVD-
>tr|R5MP73|R5MP73_9FIRM DNA gyrase subunit A OS=Firmicutes bacterium CAG:884 GN=gyrA PE=3 SV=1
DESLIPVEDIIVTLTNKGYIKRVTSDTYKSQNRGGVGIKGMTT-EEDFAEHMINMTTHDYLMFFSNKGRVYRMKGYEVPLS-RQSKGLPIINLLPLAKDE
KIKAMTMVS---KNEYLVFCTQNGIVKRTPLEEFENIRTSGKIAISLREDDELISVNKTNGSNEVMLATSDGRMIRFV---IRVMGRTASGVKGINV---
-KCIGMEIF--DQLVLIITENGYGKKTNVSEYRMTHRGSKGVKALNITE-KNGNIVAFKAIK-DCDLMIITNSGTIIRLPLNQVSK-GRVAQGVKLINLR
-DKVGSAEIVA-
>tr|R6SQV4|R6SQV4_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:417 GN=gyrA PE=3 SV=1
DESLIPVDDIIITLTHNGYIKRLKSDTYKTQNRGGVGIKGMTT-EEDFVEQLVSMKTHDYILFFSNKGRVYRMKGYEVPES-RQSKGLPIINLLELDKDE
NISSIVSVND--EYKYLLFVTRNGLVKRTELTEFDNIRKSGKIAIVLKDNDELISVRKTTGNNEVAIGASNGKMVRFV---IRSMGRTASGVKGMDL---
-LVVGAEVV--GQLILIVTESGYGKKTSIDEYRLTHRGSKGVKALNVTD-KNGMMVALCTVDSKQDVMIITDSGMVIKMPLNQIST-KRATQGVRLINLK
-EKVATIAVVD-
>tr|R6D6V1|R6D6V1_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:594 GN=gyrA PE=3 SV=1
DESLIPVEDIVVALTHKGYVKRMARDTYKLQNKGGVGIKGMST-EEDFVEILKSGKTHDHVMFFTNKGKVYRLKGYEIPES-RQSKGLPIINLLPIEKDE
KINSILLDD---NNKYLVVATKYGLVKRTNVSEFENIRKNGKIAVTLKDGDEVLSVHFTSGNDDVIIAANNGRMIRFN---IRVMGRTATGVKGIELI--
-YCVGCEIA--GQEVLVVTEKGYGKRTDINEYRLTHRGSKGVKTLNITE-KNGTIVAFRTIT-DKDLMIITDQGIVIRISADKVSR-SRVTQGVRLMNLR
-GKVSTVSVVE-
>tr|R5A226|R5A226_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:1000 GN=gyrA PE=3 SV=1
DESLIPQEEVIVTVTNKNYIKRIPKDTYKTQNRGGVGIKGMTT-DEDFVEQLISLNTHDYVLFFSNKGKVYRLKGYNIPES-RIGKGLPLINLIQIEKDE
RINAIIKVE---TYKCLLFSTKQGLVKRTLISEFNNIRQSGKIAISLKDGDELISVKKTTGNDQILMCSSNGRMARFN---VRIMGRTATGVKGINL---
-ICVGAEVS--NKYLLVVTENGYGKKTIVNEYRETKRGSKGVKTLNISE-KNGKIVGFKSTD-DKDLMIITENGIIIRMSVSNVSE-GRVTKGVKLINLK
-NKVASISIVD-
>tr|R7MGZ2|R7MGZ2_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:628 GN=gyrA PE=3 SV=1
DESLIPEQDVIVTISNKNYIKRMSTDNYKTQNRGGVGIKGMST-DEDFVEQMINLSTHDYLLFFTNKGKVYRLKGYEIPES-RISKGLPIINLIQIEKGE
NVSAVVKVK---VYKYFIFGTKDGVIKRTLISEFDNIRQSGKIAITLRDGDELNSVKKSTGEDFVLMCSSNGRMVRFN---VRVMGRSAAGVRGITL---
-YCVGTEVA--SQEVLVVTEKGYGKKTAVSEYRQTKRGSKGVKTLSITE-KNGIIVGFKSVY-DCDLMIITNSGIIIRLDMLSIST-GRVTQGVRLINLK
-NSVSSISVVS-
>tr|A0A023WZQ3|A0A023WZQ3_9ACTN DNA gyrase subunit A OS=Rubrobacter radiotolerans GN=gyrA PE=3 SV=1
VEDLIAEEEMVISISKGGYLKSVPVNTFRKQGRGGVGVAGMDL-EGDYIDHLFITTTHHYMLFFTNKGKVYRLKVHQMPRMSRTAKGRHIANLL-PAQGE
RIAAVKATK---EADYLVFATKEGTVKKTRFQDYNTLKNDGIIAINLAEGDELIDVR-ASEGDEIILVTRDGKAMRFRQ--ARAMGRATGGVKGVTLR--
-D-----VLSMAADLFMITEKGFGKRTPLSQFPTKGRGGQGVIAM--DG-ERGRLAGVQVVKPTHELMLVSNVGTTIRMDCASVSQQGRAAQGVRVMNLR
-GTVSALAKVV-
>tr|Q1B041|Q1B041_RUBXD DNA gyrase subunit A OS=Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) GN=gyrA PE=3 SV=1
VEDLIAEEEMVISISHEGYLKSVPIGSFRKQGRGGVGVAGMEL-EGDYIEHLFITTTHHYMLFFTNRGKVYRLKVHQLPRMGRAAKGRHVANLL-PAPGE
RIAAVISTR---EAEYLLFATRRGMVKKTPFRDYNTLKNEGIIAIKLAGGDELIAVR-ASDEDEVVFVTRDGKGLRFRQ--VRPMGRATAGVKGITLK--
-D-----LLSMAADLFMVTEKGFGKRTAISEFRPQGRGGQGVIAM---G-ERGKIAGVQVVRPLHELVIVSNMGTTIRIDSDSVPRQGRAAQGVRVMNLR
-GSVSALAKVV-
>tr|K2FZ82|K2FZ82_9BACT DNA topoisomerase (ATP-hydrolyzing) OS=uncultured bacterium (gcode 4) GN=gyrA PE=4 SV=1
PKDTIPNEDIVISLSKNSYIKRMKSSLFRTQRRGW-W---VA--ED-EVKFLLSTKNHNDLLFFTNTGRVFSLPAYEIPEQ-RAAKWQPIINLL-SQD-E
D--TILDMN--INGKHFVLITKNAIVKRLDLEDVQN-R-SGLIVMKPK--DELGW---TD---NVLIVSKKWKAI------VRVMGRAAAWVRWMRMWK-
-DVIEADVVSE-KYVFTVTENWLGKMTDI-GYR-QWRWWSWVKVW---TAKTGDI-WVSLLT-NWEVLLISKNGQTIRIAL-TIRV-SR---GVILTKIK
K-VLISATVMK-
>tr|K2BXA1|K2BXA1_9BACT DNA topoisomerase (ATP-hydrolyzing) OS=uncultured bacterium (gcode 4) GN=ACD_49C00008G0003 PE=4 SV=1
PRDTIPNEDIVITLSKNSYIKRIKSSAFRTQRRWG-W---VA--ED-EVKIIISTKNHNDLLFFTNTWRVFSLPAYEIPEQ-RTAKWQPIINLF-NQD-E
D--SILDMA--IKWKFLILITKNAVVKRLDIEDVKS-R-SGLIVMKPR--DELGW---TD---NLLIVSRKWKAI------VRVMWRAAAGVRWMRIAK-
-EVIEADVVSE-KYVFTVTANWLGKMTDI-EYR-QGRWGSWVKVW---TAKTGDI-WVNLLT-NWEVMLISKSGQTIRLAL-TLRI-SR---WVILTKIK
K-VLTSATVMV-
>tr|D1AVF2|D1AVF2_STRM9 DNA gyrase subunit A OS=Streptobacillus moniliformis (strain ATCC 14647 / DSM 12112 / NCTC 10651 / 9901) GN=gyrA PE=3 SV=1
IEDLIKNEDVIVTITKRGYAKRMSLDSYKAQKRGGKGVSNTTT-EDDVLKDLFTAKTLDTLMVFSDKGKVYSIKVYEIPEVSKQARGKLIGNIIELDENE
KISVIIP---INDNRDLIFITRNGIAKKTKISEFKTINRNGKIAISFKDDEDEVKIT-GSEKDEIFISTKGGMAVRFKE--IRSMGRTAAGVRAIKLN--
-DVVSADVIYTEMSVLSVTSLGIGKKTLLSEYNIIKRGGKGVKNY--ER--SKEESYSDENSENMELVAISTTGTVIRIKIKDLPVVGRNSKGVKIQSLK
-KYLVSADRVA-
>tr|K9XQ85|K9XQ85_STAC7 DNA topoisomerase (ATP-hydrolyzing) OS=Stanieria cyanosphaera (strain ATCC 29371 / PCC 7437) GN=Sta7437_0613 PE=4 SV=1
VFNIEREPNATIAITHQGCIYWQNPTQEQEL--L-----S----ED-FVVQTELINDREQVIVITDSGKAYPLNIEEIPAI-QA-QNVTALNLLSKAA-S
-STAHFFLP--DKNLDLILLTEKGMIKRLPVSELTN-G-RGLVLIKLK--DRLKY---K----EVAIATTGGRIL------IPILGRNAQGNQ-LKLR--
-GIVGCVTLRS--KLLLVTQSGYGKCIPA-ALR-ASRGDIGTQAI--SKT---DL-GMILAQS---IMVTTNNEQKLVIAI-QVNL-GT---GNKLVKLQ
Q-IVTELTRLN-
>tr|R6BXE1|R6BXE1_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:510 GN=gyrA PE=3 SV=1
MEDLVPRGNTVIAMTKLGYIKRMTVDNFKAQNRGGKGIKGMQT-DEDYIEDLLMTTTHHYLNFFTNQGRVYRLKAYEIPEAGRTARGVAIINLLNLNP-E
KITAMIPIS---DNKNLFMITKKGIAKKTPLMEYSN-RKNGLAAINLREDDELIEVK-TDK-SEIFLVTKFGMCIRFLE--VRATGRTSMGVIGMNLS--
-GIVGMQLASQGDSLLIASENGLGKRTPMDEFTVQKRGGKGVKCYKIT-D-TGEVVGVKAVND-NEIMMITTEGIIIQLRVQEISTLGRITSGVKLINLK
G-KVAQIAKVR-
>tr|R6ELP4|R6ELP4_9FIRM DNA gyrase subunit A OS=Firmicutes bacterium CAG:65 GN=gyrA PE=3 SV=1
MEDLIPKENTIIAMTSLGYIKRMTVDNFKAQNRGGRGIKGMQT-DEDYIEDLLMTTTHHYLNFFTNMGRVYRLKAYEIPEAGRTARGTAIVNLLQLAP-E
KITAMIPIH---DDKNLFMVTKTGIVKKTPLMEFSN-RKNGLTAINLREEDELIEVK-TDS-SEIFLVTKQGMCIRFQE--VRATGRASMGVIGMNLS--
-GIIGMQLQTQGSDLLIVSENGMGKRTNMDEFTVQKRGGKGVKCYKIV-E-TGDVVGAKAVND-NEIMMITTEGIIIQLRVQDISTLSRITSGVKLINLD
G-KVAQIAKVR-
>tr|A0A0G3GST1|A0A0G3GST1_9CORY DNA gyrase subunit A OS=Corynebacterium epidermidicanis GN=gyrA PE=3 SV=1
EEDLIARENVVVTITSTGYAKRTKVDAYKSQRRGGKGVRGA-EKQDDVVRHFFVCSTHDWILFFTNYGRVYRLKAYELPETSRTARGQHVANLLEFQPGE
QIAQVIQIQ---AE-YLVLSTQQGRVKKSRLLDYES-RSGGLIAINLNE-DKLIGAA--SGDDELVLVSEEGQSIRFRE--LRPMGRATAGVKGMRFR-D
-DLLSMCVVR-GEYLLVATSGGYGKRTSMEEYSVQGRGGVGVVTFKYN-AKRGKLIGALAVDD-DQIFAITSGGGVIRTEVNQIRP-SRATMGVRLVDLP
-GELLAIDKNV-
>tr|A0A0F2STA5|A0A0F2STA5_9ACTN DNA gyrase subunit A OS=Streptomyces rubellomurinus subsp. indigoferus GN=gyrA PE=3 SV=1
IEDLIAEEDIVVTITRGGYVKRTRSDLYRSQKRGGKGVRGA-QKQDDIVDHFFVTTTHNWILFFTNKGRVYRAKGYELPDAGRDARGQHVANLLAFQPEE
HIAQVMAVR---KP-YLVLATRAGLVKKSPLKDYDS-RSGGLIAINLRQDDELIGAE--SSEDDLLLVSKKAQSIRFTD--LRPTGRATSGVKGMAFR-D
-DLLSMNVVRPGTYVFTATDGGYAKRTAVDEYRVQGRGGYGTKAAKIV-EGRGSLVGALVVDT-DEIMAITLSGGVIRTRVSEVRE-GRDTMGVQLINLG
-RAVVGMARNA-
>tr|J9HFN9|J9HFN9_9ACTN DNA gyrase subunit A OS=actinobacterium SCGC AAA027-L06 GN=gyrA PE=3 SV=1
VEDLIPDQDVVVTITKGGYSKRTKADAYRAQKRGGKGVKGA-AKTDDVVEHFFTASTHNWLLFFTNKGRVYRAKVHELPDAGRDARGQHVANLLAFKPDE
SIAQVIAIA---QP-YLVIATKAGIVKKTPLVEYDS-RSGGLIAVSLKP-DEVVSAT--SEKEELLLVSKMGMSLRFSE--LRPMGRGATGVIGMKFR-G
-DLLAMAAISSKNYVFTATDGGYAKRTKLEEYRTQGRGGIGVKAAKID-ESRGVLVGAMIVQS-DEILAISSAGTVMRTPLTQIRE-GRDTLGVRLVNLD
-GSVVSVTRLV-
>tr|A0A094QH35|A0A094QH35_9ZZZZ DNA gyrase subunit A OS=freshwater metagenome GN=GM50_21820 PE=3 SV=1
AEDLIPDQDAVVTITRTGYAKRTNADLYKTQRRGGRGVKGA-AKQDDVVDHFFVASTHDWLLFFTNQGRVYRAKVHELPDAGRDARGQHVANLMAFKSDE
TIAQVLSIK---SP-YLVLATKTGLVKKTPLTEYDS-RTGGLIAISLKPGDEVVSAA--NKDDELLLVSKKAMSLRFAE--LRPMGRSTSGVIGMKFR--
-GLLTMARIDSSSFVFTATDGGYGKKTPLDEYRLQGRGGIGIKAAKID-ESRGSLVSALVLAT-DEILAITSAGTVMRTPAAEVRQ-GRDSMGVRLVNLD
-GALVSVTQNQ-
>tr|R7J8Z7|R7J8Z7_9PORP DNA gyrase subunit A OS=Parabacteroides sp. CAG:409 GN=gyrA PE=3 SV=1
PEDFYADDEMIITISHMGYIKRTPLADFKAQGRGGIGVKGSET-DEDFIEYIYPASMHATMMFFTSKGRCFWLPVYQIPEGTKNAKGRAIQNLLNIEADD
KVQAFIRVKT--NSHYLLFCTKKGIIKKTCLEAYSR-RQNGVNAITLREDDGLIQVCMTNGDREVLIANRNGRAIRFH---VREMGRTASGVRGMTLDDG
-DVVGMVCIKDKETTLVVSEQGYGKRSHI-DYRITNRGGKGVKTLNITE-KTGKLVAFLNVT-ENDLMIINKSGITIRTKVSDLSIIGRATQGVRLINLG
RNEIASVCKVL-
>tr|E0UDS6|E0UDS6_CYAP2 DNA topoisomerase (ATP-hydrolyzing) OS=Cyanothece sp. (strain PCC 7822) GN=Cyan7822_4603 PE=4 SV=1
FTPQTPPADALLTITYQGYIYWQSSVQATDS--------A----ED-FPIYRQAIAQKELLIVITNQGKAYPISVVDIPPK-DS-QACSLLSLLPNAA-E
-KVGYFFLP--KNTHELILLSQQGRIKRLPLSELNQ-G-RGLALIKFK--DELSY---S----EIAIATTGGRIL------LSLMGRNAQGNQ-LRLR--
-GLAGCVTTKA--YLVLITQLGYAKRLPV-SLR-TKLGEIGTTAL--SKT---DL-GIVLNQK---VALITNQQRRLILSA-SVGI-GK---GDRLVKLK
E-SIVLVVGC--
>tr|L8LMA8|L8LMA8_9CHRO DNA topoisomerase (ATP-hydrolyzing) OS=Gloeocapsa sp. PCC 73106 GN=GLO73106DRAFT_00017760 PE=4 SV=1
--PSVPEVKGIVAVTDTGCVYWQESEQ-----------------NQ-GVIFS-QKIDDQPLVVITDQGKAYPVALESIPHR-ENP-SQLLLRLLPKSS--
---TQFFPP--ESGSDLLLVTQQGRLKRLLMSELDG-T-RGLMLLKLK--DRLAY---D----EVVIATKKGRIV------IPLLGRSAQGITGLILR--
-GLVGCATIK-EKHLILVSELGYGKRLPI-ALR-CAPGDMGTQAF--IPL---DL-GILPEK-NSTVSLSLG-RDKKQIAV-DIPV-PK---GIQLVKLK
Q-KILNIYYQ--
>tr|A0A0D6AS83|A0A0D6AS83_9CHRO DNA topoisomerase (ATP-hydrolyzing) OS=Geminocystis sp. NIES-3709 GN=GM3709_2508 PE=4 SV=1
LLNQPLPEDAIAQITAKGKIYWQRQNEIDTT--------P----TD-LIVYQELIGKQEQIIAFFDSGKAYPIPTAEIPPP-AK-QTI--EKLVSNSN-H
-QPNYLCLH--TK-SSLLLLTKGGFLKRVSIQELDG-G-RGFQLIKLK--DSLKY---N----ELAVATNGGRLL------MSIMGRSAQGSI-IKLK--
-GIVGCLGVNN--NIALISQLGYAKILPI-TIR-VNLGQLGTQAF--KKN---DL-SILSIDN---IIVKTNLDGRHLIDV-KLTP------EKSIVKLQ
E-IIILALNWF-
>tr|K9YK80|K9YK80_CYASC DNA topoisomerase (ATP-hydrolyzing) OS=Cyanobacterium stanieri (strain ATCC 29140 / PCC 7202) GN=Cyast_0534 PE=4 SV=1
ITSQELTDDAVVQISAKGKVYWQPQSAILDQ--------P----TD-LIIHQELIDKQE-IIVILDSGKAYPLTVADIPRP-TK-QTI--SRLISESN-H
-QPNYITIT--NTHQSLVLLTAGGFIKRIAMDELDN-G-RGFTLIKLK--DALHS---H----ELITATSGGRLL------MSIMGKSAQGNI-VKLR--
-GIIGSAVVEK--NVLLISEMGYGKIVPI-NLR-LGTGGLGNQSF--KED---DL-SMLLPCI---VIATTDLDKRLIIDT-KLFN-N----ERAIVKLA
G-KITFALNWW-
>tr|K9Z515|K9Z515_CYAAP DNA topoisomerase (ATP-hydrolyzing) OS=Cyanobacterium aponinum (strain PCC 10605) GN=Cyan10605_1556 PE=4 SV=1
DFSQKMPEDALIHITAKGKIYWRKPATISDT--------P----TD-LVIYQQTVPKAEKLIVFFDSGKAYPLSLPDIPAP-TK-QTI--DRLVSNSD-A
-KPAYLCLE---KANGLLMLTQGGYVKRISISELDG-G-RGFQLIKLK--DSLQF---S----EAAIATNGGRIL------VATMGKSAQGNV-IKLR--
-GIIGCEKVDS--NLLLISALGYGKLLPI-SLR-IRLGDLGNQAF--KKE---DL-NILLADT---LVAKTETDNRYLLDI-KLSI-N----EKSLIKLT
D-KIELTIKWW-
>tr|B7K4F6|B7K4F6_CYAP8 DNA topoisomerase (ATP-hydrolyzing) OS=Cyanothece sp. (strain PCC 8801) GN=PCC8801_1360 PE=4 SV=1
FTPQPPPENAILEINHQGEASWRLPDGQ-------------------SPIFRAIIGQKSELMVITDAGKAYPVAVAEIPPL-TL-QAIPLLSLLPKGA-N
-RVDAGFVP--PHGYDLLLLTQQGRIKRVKMSELSD-T-RGLVLIKLK--DRLGF---Q----EVAIAISGGRIL------IPLMGRSAQGNQ-LKLRN-
-GVVNCLTLHS--EVLLISSLGYGKRLSL-ELR-GKLGDLGTQCL--TKT---DL-GMIAAKQ---VRCLTNQNRSLAISV-TILP-GK---GDRLVKLQ
E-VITTVLG---
>tr|A0A077JES8|A0A077JES8_9CYAN DNA topoisomerase (ATP-hydrolyzing) OS=cyanobacterium endosymbiont of Epithemia turgida isolate EtSB Lake Yunoko GN=gyrA2 PE=4 
FSCQKPPEDAILEITHNSEVAWRSPGNK-------------------HLVYSATIGRQTKLIVITDASKAYPLTVSEIPPV-TI-QSVSLLSLLVKVV-N
-RVYSGFLP--LENQDLLLLTKLGRIKRIAMSQLTR-T-RGLMLVKLK--DYLDY---Q----AVVIATSGGRVL------IGVMGRNTQGNQ-LTLR--
-GLVGCVTLNM--DILLISSLGYGKRLSS-DIR-GKLGDIGHQCL--KKT---DL-GMILTKE---ITLLTDYNRSLVVPI-SIPF-GK---GDRLVKLQ
E-TIITVLN---
>tr|A3IV74|A3IV74_9CHRO DNA topoisomerase (ATP-hydrolyzing) OS=Cyanothece sp. CCY0110 GN=CY0110_24421 PE=4 SV=1
FTPQTPPKNAILEMTYQGTICWRSPDTK----------------NH-VSIYSEAIQEREQFIVITDIGKAYPVNVADVPPI-DI-QPIPLLSLLSKTS-K
-KVSLFFLS--TDNKDLLLLTNQGKIKRVQLSELEG-T-RGLVLIKLK--DSLES---K----EVAIAMSSGRVL------IPIMGRNAQGNQ-LKSR--
-GIVSCVTLDE--IVLLVSKLGYGKRLNI-GLR-TKLGDIGTQAL--TKQ---DL-VMIKATD---ITLLTNQKKTFNIVA-DVKV-SK---GDRLIKLS
Q-VIDHVI----
>tr|T2J2H1|T2J2H1_CROWT DNA topoisomerase (ATP-hydrolyzing) OS=Crocosphaera watsonii WH 0401 GN=CWATWH0401_1576 PE=4 SV=1
FTPQTPPKNAILEMTYQGTICWRSPDDK----------------KH-LLIYSEPIQEREQFVVITDIGKAYPVNVADVPPI-DI-QPISLLSLLPKSS-K
-KVSVFFVL--KENHDLLLLTNQGKIKRIQLSELDG-T-RGLVLIKLK--DYLEF---K----EVAIAMSSGRVL------IHIMGRNAQGNQ-LKLR--
-GIISCVTLDE--TVLLVSKLGYAKRLNI-GLR-TKLGDIGTQAL--AKT---DL-GMIKASN---VTLLTNQNNTVNIVA-KVRI-GK---GDRLIKLS
Q-VIDYLI----
>tr|M1WYX5|M1WYX5_9NOST DNA topoisomerase (ATP-hydrolyzing) OS=Richelia intracellularis HH01 GN=RINTHH_1330 PE=4 SV=1
GISEQPLKPTILEFTYRGYVRCYQ---------AS-K--SGDR-HD-FTIQTDVTDRAQDLLVLTNTGKVYPISVESIPIV-GRVKRTPLITLLSNAQ--
---SHFLVP--K-DTDLILLTKQGKIKRLDISKLKQ-S-RGTTIIKLK--DELLC---F----HLTIASSGSRLL------LPKMERAAIGLQGIRIL--
-SMVDCITLD-NQNILLFTQNGYSKCLNT-EIK-AHRGDLGTQAM--NRT---DL-AMVAAQ-DDEVIIFTNKDRAELLKV-QIPL-GR---GEIVITLS
D-KIVSVINAR-
>tr|B1XQN0|B1XQN0_SYNP2 DNA topoisomerase (ATP-hydrolyzing) OS=Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) GN=gvrA PE=4 SV=1
ALLPQLTETSHVAIAASGGVYWGNDDAG----------------EE-PTIFKAQIGTQKKLIVCTDQGKAFPVAIADLPYE-QR-DKPQLIDLLPDHD-H
-QPTQFLLP--LAEYDLLLLTAQGRIKRLPAIELES-T-RGLSLIKLK--DTLKF---K----QVAIAVSSGRVL------IPVMGRTSQGNQ-LRLR--
-NIVACVPCQR--ELYLISEEGYGKKLAA-SLR-GKRGDMGNHVM--EKT---DL-TLFVPDS---LLVKDSQENLDLLPF-KFNL-EK---GQKLVKLS
G-RLVNCYLSG-
>tr|K9Q0V2|K9Q0V2_9CYAN DNA topoisomerase (ATP-hydrolyzing) OS=Leptolyngbya sp. PCC 7376 GN=Lepto7376_2522 PE=4 SV=1
NLLPQRSETSHVAIAADGSACWGNDDAG----------------ES-ATLYKAAIGTQENLIVCTDQGKAYPVAIADLPYE-QR-DKPQLQSLLPDHN-H
-QPTQFVLP--LEELELLLLTTKGKIKRLAGTELSS-T-RGLSLIKLK--DTLQF---Q----RVAIAVSSGRVL------IPVQGRTSQGNQ-LKLR--
-NIVGCASFQR--EIFLLSEEGYGKRLEV-SLR-GRRGDMGNHVM--EKT---DL-KMFIPDQ---LWTQDSRENVELISV-KFPV-SK---GRRFFKFT
G-RLVTAQLAY-
>tr|B7KIH9|B7KIH9_CYAP7 DNA topoisomerase (ATP-hydrolyzing) OS=Cyanothece sp. (strain PCC 7424) GN=PCC7424_0929 PE=4 SV=1
FTPQPPPKDAVLTITEQGYIYWQSAAE-FNS--------S----TD-FPIYTQRIQQQDSLIVITDQGKAYPVSGSEIPPQ-ES-QPCSLLNLLPNSS-Q
-KISYFLFP--KNLSELILLTGQGRIKRLSMSELEQ-G-RGLSLIKLK--DRLGY---S----EVAIATNGGRVL------IPLMGRNAQGNQ-LRLR--
-GIVGCVTPKI--NLLLITQSGYGKRIPV-SLR-TKLGEIGTMAL--SKT---DL-GMILAKE---VILVTNQERRLIIPI-SVGI-GK---GDQVVKLK
Q-SILLVVAL--
>tr|K9T574|K9T574_9CYAN DNA topoisomerase (ATP-hydrolyzing) OS=Pleurocapsa sp. PCC 7327 GN=Ple7327_2783 PE=4 SV=1
LFSQTPTEDAVLEITQQGYIYWHP---------PE-D---QSL-ND-FVISTQTIGKQEQLLVITDSGKAYPVEIKDIPPL-GRE--KTLIGLLPKSA--
---AHFFLP----NIDLIFLTQKGKIKRLPVSELDN-G-RGLSPIKLK--DRLRY---R----DLAIATTGGRLL------IPVLGRGAQGNQILRLR--
-GIAGCVALD-DENLLLVSQLGYGKRLPI-LLR-AKLGDIGTQAM--TKT---DL-GIVLAK-KAKAVLVTSRDRGISLSV-SVAV-GK---GDRVATLK
D-AIVSVIGG--
>tr|E6PRJ3|E6PRJ3_9ZZZZ DNA gyrase subunit A OS=mine drainage metagenome GN=gyrA PE=3 SV=1
IEDLITPQDMVVTISHVGYIKSQPMDEYRAQRRGGRGLATG-TKEDDWIDQLFVANTHAMLLCFSNRGRVYWMKVYEAPQGGRGSRGRPLVNLFPLA-GE
KITVVLPVKAF--DHFVFMATARGTVKKTPLSAFANRRTAGIIACGLDDDDYLVGVAITDGQHDVMLFSDSGKAVRFDE-DVRPMGREARGVRGMNLE--
DGVIAMLVAEDSQSVLTATENGFGKRTSIVEYTRHGRGTKGMIAIQTSE-RNGKVVAACLVRADDEIMLITDTGVLVRTRVAEIRELGRATQGVTLIALD
DKQLIGVQRVA-
>tr|D5X294|D5X294_THIK1 DNA gyrase subunit A OS=Thiomonas intermedia (strain K12) GN=gyrA PE=3 SV=1
VEDLITPQDLVVTISHSGYVKSQPLAEYRAQRRGGRGLATG-TKEDDWVEQLFVANTHDMLLCFSNRGRVYWMKVYESPMGGRGSRGKPLVNLFPLQ-GE
KITTVLPVKAF--QHYVFMATARGTVKKTPLTAFANRRTAGIIAVGLDDDDYLIGAAITDGQHDVMLFSDAGKAVRFDE-DVRPMGREARGVRGMQLE--
ADVIALLVAEDTQSVLTATENGFGKRTSITEYTRHGRGTKGMIAIQTSE-RNGKVVAACLVRTSDEIMLITDTGVLVRTRVEEIREMGRATQGVTLIALD
AKHLIQVQPVV-
>tr|A0A0Q8C4C6|A0A0Q8C4C6_9MICO DNA gyrase subunit A OS=Leifsonia sp. Root60 GN=ASD61_13095 PE=4 SV=1
VEDLIPEEEMVVTITRGGYVKRTRSDNYRNQHRGGKGVKGA-ARGEDVVEHFFVTTTHHWLLFFTNMGRVYRAKAYEIQEGGRDAKGQHVANLLELQPDE
QIAQVLDIR---AQ-YLALATRDGLVKKTALEEYDT-RSRGVIAVKLREGDELVSAM--DQGDEILLVSRKGMSLKFAS--LRPMGRSTSGVKGMDFR-G
-DLLSASVVPAPASVFVVTEGGYAKRTSVDQYRVQNRGGLGIKVAKLS-E-RGDLVGSLIVAE-DEVLVVLASGKVIRSDVAEVNR-GRDSMGVIFAKFA
-SRIIAIAKNT-
>tr|A0A0Q6Y070|A0A0Q6Y070_9MICO DNA gyrase subunit A OS=Leifsonia sp. Root4 GN=ASC66_15065 PE=4 SV=1
IEDLIPEEEMVVTVTRGGYVKRTRSDNYRSQHRGGKGVKGA-QRADDVVEHFFVTTTHHWLLFFTNAGRVYRAKAYEIQEAGRDAKGQHVANLLEMQPDE
EITQILDIR---AT-YLVLATRDGLIKKTALSEYDT-RSRGIIAIKLREGDALVSAM--NEDDDVLLVSRKGMSIRFKE--LRPMGRSTSGVGGMHFR-D
-DLLDASVVS-EGYVFVVTEGGYAKRTSVDQYRLQNRNGLGIKVAKLS-E-RGDLAGAIIVEQ-DEVLVVLASGKVVRSDVAEVPA-GRDTMGVVFAKFA
-DRIIAIAKNT-
>tr|A0A0Q8W6X4|A0A0Q8W6X4_9MICO DNA gyrase subunit A OS=Agromyces sp. Root81 GN=ASE14_11900 PE=4 SV=1
VEDLIPEEEMVVTVTRGGYVKRTRSDNYRSQHRGGKGVKGA-QRADDVVEHFFVTTTHHWLLFFTNMGRVYRAKAYEIQEAGRDAKGQHVANLLEMQPDE
QIAEILDIR---AQ-YLVLATREGLVKKTELTAYDT-RSRGVIAINLRDGDELVSAM--DEHDEILLVSKKGMSLRFEA--LRPMGRSTSGVKGMSFR-G
-DLLEASVVAAARFVFVVTEGGYAKRTAVDQYRLQNRGGLGIKVAKLS-E-RGDLAGALIVGD-DEVLVVLASGKVVRSDVAEVPA-GRDTMGVVFAKFA
-DRIIAIAKNS-
>tr|B0CDP0|B0CDP0_ACAM1 DNA gyrase subunit A OS=Acaryochloris marina (strain MBIC 11017) GN=gyrA PE=3 SV=1
DIDLIANDQAVILVTEQGYVKRMPVDTFNAQSRATRGRAGAKI-EDDAVEHFFGCCDHDSVLFFSDRGVVYCLRAYQIPVSSRTARGVPLVQLLPIPREE
KITSVIPVS---EDEYLVMMTAGGFIKKTALAAFSNIRANGLIAISLEEGDLLRWVRLTRAEDSIVIGSRRGMSIHFRA--LRPLGRATRGVRAMRLR--
-DFIGMDILSSGPWVLVITTNGFGKRVPVAQFRLQNRAGKGVTATKFLKT-PDQLAALRIVN-EDELMLVTSRGIVIRQAVTDISSQSRAATGVRVQRLD
-DYIAAVALVP-
>tr|K9Q432|K9Q432_9CYAN DNA gyrase subunit A OS=Leptolyngbya sp. PCC 7376 GN=gyrA PE=3 SV=1
DIDLIANERSAILLTEQGYIKRMPVATFDAQNRATRGKAAAKM-EDDGIDHFLTCCDHDHVLFFTDRGVVYSLHAYQIPESSRTARGLPAIQLLPIPKEE
KITSMIRVS---EDEYLVMLTQNGYIKKTTLSAFARIRSNGLIAISLEDGDQLNWVRLARQEDSIIVASSEGMAIHFQA--LRPLGRSTRGVRAMKLK--
-DLVSMDIVSAGPWVVAVTTKGFGKRVQVGRFRLQNRAGVGLRAIKF--K-GDRLASLRIVH-GNELMLVTSRGIMIRQAVESISLQSRNATGVRVQRLD
-EAIVAVALVP-
>tr|M5E2K1|M5E2K1_9FIRM DNA gyrase subunit A OS=Halanaerobium saccharolyticum subsp. saccharolyticum DSM 6643 GN=gyrA PE=3 SV=1
LEDLIEEEQIVVTMTNQGYIKRMALDLYRSQRRGGKGVIGIST-EEDFVENIFTTTTHHKFLFFSNQGRVYRLKGYQIPE-GRQARGTAIVNLLELEKDE
KINTVIPVK-F-KDAYLIMATKNGLIKKTALEEYDT-NYTGLIAVNLRENDELIGVRIIEENENIFLITKNAKAIHFS---VRSVGRNSYGVKGINLE--
-KVIDMGID--GNELLVITENGYGKRTPISEYRIQNRGGKGILTANITD-KNGKLAAARIVE-GLEMMVITQDGIIIRVDVDEIST-GRNTMGVKIINVG
-DKVVSLARIN-
>tr|L0KA32|L0KA32_HALHC DNA gyrase subunit A OS=Halobacteroides halobius (strain ATCC 35273 / DSM 5150 / MD-1) GN=gyrA PE=3 SV=1
KKDLIKDKEAVISLSYNHKLKRTDDKENV---RA----------ND-YITQVLSGRSHNKLLFFTQTGQVHLLKIHKIPEH-SLSTGDHLSEFIKF-D-E
K--DVLILN--VEDDFITIATKNGLVKKTVGKEYKT-S-SSLKAINLE--DEVIG---TQ---KLLLGTKEGYTI------ISPTGRNTKGRKGINLE--
-NVINLNVT-NEEVVISLTENGRGKASPI-DYN-QQRNGKGLKTM---DDY--QL-NIIS-A-NEKIILVTDKGQVIEKNV-DITT-ER---MYSQINLK
E-KLVQIIKLP-
>tr|L0K4U9|L0K4U9_HALHC DNA gyrase subunit A OS=Halobacteroides halobius (strain ATCC 35273 / DSM 5150 / MD-1) GN=gyrA PE=3 SV=1
LEDLIEEEEIVVLSTEEGYIKRMTLDTYRKQHRNGKGIIGTKP-EDDLVQDVQIGSTHDYFLFFTNQGYVHKLKGYQIPES-RQARGIPMINLLDLDL-E
KVATIFPMS---DEEYLFMATKDGIVKKTSIEDFNT-SYAKLIALSVDEDDRLVDVE-TSG-EEIILATKDGLAIRFSE--VRSMGRTARGVKGIELD--
-NLIGMEVIRD-GDLLVITEKGYTKRTSIDEYSLQGRGGKGLITLKQT-E-NGKIIDIKMVDL-EDIVLVSAQGILLRTLVNEISVTGRNTQGVRCMRLN
ND-VVGVDTVN-
>tr|D9QSA4|D9QSA4_ACEAZ DNA gyrase subunit A OS=Acetohalobium arabaticum (strain ATCC 49924 / DSM 5501 / Z-7288) GN=gyrA PE=3 SV=1
VEDLIEEEEILITITDNNYIKRIPLDTYRSQHRGGRGIIGINP-AKDSVEQLYTTSTHDYLLFFTNQGRTYRLKGYQIPDS-RQAKGTAIINLLDMEP-E
RVTAVIPVE---LDDYLLMVTEQGIVKRTELQEFNT-NYTGLIALDLQQNDELIEVR-TTG-EDIILGTELGLAIRFNE--VRSMGRTARGVKGIDLA--
-QVVGADIIKD-GKLLVVTDKGYGKQTPLNKYRRQSRAGKGLLTIKRT-D-NGKLTALKVVED-DEVMLISKEGIVIRMSVSEISSTSRNTQGVNLMSLV
GD-VVSLAHIE-
>tr|B8CZP0|B8CZP0_HALOH DNA gyrase subunit A OS=Halothermothrix orenii (strain H 168 / OCM 544 / DSM 9562) GN=gyrA PE=3 SV=1
VEDLIPEEQVVITLTHHGYIKRMPIDIYRSQRRGGKGIIGINT-EEDFVEHVFTTSTHHYFLFFTNKGKVYRLRVFEIPQS-RQARGTAIVNLLELEE-E
RITTVIPIR---EERYLVMVTRNGMIKKTPLAEYES-RYTGLIGLTLRDEDELIDVK-TDG-QSVIIVTHRGKAIHFKE--VRSMGRTAMGVKAITLE--
-GVVGMGVDSE-DDLLVITEKGYGKRTPLEEYRLQSRGGKGLITANIT-E-NGNLAGVKVVRD-HDLILITSEGIIIRTRVEGISRLGRNTLGVKVIRLE
GD-VVSLARIS-
>tr|E4RNH2|E4RNH2_HALHG DNA gyrase subunit A OS=Halanaerobium hydrogeniformans GN=gyrA PE=3 SV=1
IEDLIEEEQIVITMTHQGYIKRMALDLYRSQRRGGKGVIGIST-EEDFVENIFTTTTHHKFLFFSNQGRVYRLKGYQIPEG-RQARGTAIINLLELKE-E
RITAVIPVK---EDAYLIMATKNGLIKKTSLDAYDT-NYTGLIGINLRENDELIGVR-IDE-ENIILVSKNAKAIHFNE--VRSVGRNSYGVRGIRLS--
-EVIDMGIDSA-EHLLVITENGYGKKTPLTEYRIQNRGGKGILTANIT-E-NGQLAAAKIVDN-SEMMVITHEGIIIRVQAEEISTTGRNTIGVKIINVE
DD-VVSLARIN-
>tr|E3DLI8|E3DLI8_HALPG DNA gyrase subunit A OS=Halanaerobium praevalens (strain ATCC 33744 / DSM 2228 / GSL) GN=gyrA PE=3 SV=1
LEDLIEEEQIVVTMTNQGYIKRMPLDLYRSQRRGGKGVIGIST-EEDFVENIFTTTTHYKFLFFTNQGRVYRLKGYQIPE-GRQARGTAIINLLELEEGE
KINAVIPIK-F-ADAYLIMATKNGLIKKTALEEYNT-NYTGLIAINLRENDELIGVRVIEAKENIFLVTRNAKAIHFS---VRSVGRNSYGVKGINLE--
-EVIDLGID--GDELLVITENGYGKRTLISEYRVQNRGGKGILTANLTE-KNGQLAAARIVD-SLEMMAITQAGIIIRVAASEIST-GRNTMGVKIINVG
-EQVVSLARIN-
>tr|D1Y742|D1Y742_9BACT DNA gyrase subunit A OS=Pyramidobacter piscolens W5455 GN=gyrA PE=3 SV=1
YEDLMPEENIVITLSKDGYLRRSLLKDYNVQNRGG-G--RAN--ED-QVAGMVVTTTHNDVLLFTSRGRVFAIKGHMVPE--KSGKGRKVEQFISL-G-E
T--EILGR---DNCSTVVLITRRGIAKRMDKSELQN-T-AGRQIMTLD--DDIAR---TD---DLFLVSAMGRGL------IRTMGRSARGVKAMKLG--
-DIISCEVI-ADSRILLVSQRGIGKITSY-EFS-HHRATGGQRAM---GDRTGRA-VANTVF-DDEVALMTAGGNIIRLAV-SIPQ-GR---GSILIRPE
G-EVANVSLIH-
>tr|A0A073IPK4|A0A073IPK4_9BACT DNA gyrase subunit A OS=Synergistes jonesii GN=gyrA PE=3 SV=1
DEDLIPEEDIVVALSRDGYIRRMPLQDYRVQQRGGKGVKGVAT-AEDEIAIIATTTTHRTLYLFTNKGRVFGVRGFSLPE-PKTGKGKLVGTIITLEKDE
KAVAIKDSN-LGGEKFVFFVTKQGTAKRLPVEELEGLTRAGRRVLGISEGDDIARVRFTSGGCDLLLTTATGQTLRVNE--FRPQGRQAQGMRGIRLD--
-AVVGCDVVAE-RQVLFISEGGIGKRTSYDEFTQHHRGGYGVRAM--SE-KTGPLVGAWGVQEDEEIIVITGKGRMVRIGAKEISSLSRSATGYMIVTLD
-GTVADISIVK-
>tr|C9M5P0|C9M5P0_9BACT DNA gyrase subunit A OS=Jonquetella anthropi E3_33 E1 GN=gyrA PE=3 SV=1
LEDLLPEEDILVTLSKDGFLRRSPLENYNLQNRGGKGRLGAVL-DDDEVGQMAVTSTHSDIFLFTSRGRVFAIRGHMIP-ETKTGKGRAVSKFVSLTDDE
RVVAMR-GT---ATSHLLFITKRGIGKRMDAEELENLTRAGRRVLSLDDGDEIAAIIDTDGNSKVLLVTSKAKAAHVDE--FRPMGRAARGVKAMKLA--
-RIIAAWTVAP--NLLLVSETGIGKRTKPEEFPIHHRGSGGVQAM--GA-RTGRLAAAVGVASSDEVGLMTEKGRMIRLSASDIPLLSRTATGSIVLRLN
-GLLASVSVIP-
>tr|Q5ZVM3|Q5ZVM3_LEGPH DNA gyrase subunit A OS=Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513) GN=gyrA PE=3 
IEDLITEEDVVVTLSHQGYVKYQPITAYQAQRRGGKGSATH-VKDEDFVERLVIASTHDTLLCFSNHGKLYWLKAYQLPQASRASRGRPIINILPLA-GE
EINAMLPVREYKDGSYVFMATKKGTVKKVPLNAFSRPRSNGIIAVDLEEDDSLVGVDITDGARDIMLFTDAGKVIRFDESKVRPMGRTARGVRGIRVEKQ
A-VKSLVVVD-GGTILTATENGYGKRTHIDEYRVSGRGGQGVISIQVTE-RNGKVVRSLQVTDNDEAMLITDKGTLVRFKVNELSVIGRNTQGVRLINVS
SGAVVGMQKIV-
>tr|K2BL93|K2BL93_9BACT DNA gyrase subunit A OS=uncultured bacterium (gcode 4) GN=gyrA PE=3 SV=1
LEDLITPEEVVITLSHEGYVKLQSLSLYHAQRRGGKGAATS-VKDEDFIEQLIIAHTHDTILCFSNHGKVYWLKSYQVPQASRIARGKPIINLLPLS-GE
RINALLPVKEYREDQYVFMATEKGTVKKVSLDHFSRPRNSGIIAIELHEGDRLVGVALTDGKQDVMLFSNAGKAIRFPEDKVRSMGRTAAGVRGISLHEQ
K-IISLIIVK--GNILTATENGYGKCTAIEEYRVTSRGGQGVISIQISE-RNGNVVGATQVTRGEEVMLITDRGTLIRTRVDEISVVGRNTQGVRLINLS
EEKLTQLQRIA-
>tr|W0B9Z7|W0B9Z7_9GAMM DNA gyrase subunit A OS=Legionella oakridgensis ATCC 33761 = DSM 21215 GN=gyrA PE=3 SV=1
IEDLITEEDVVVTMSHQGYVKYQPLSAYQAQRRGGKGSATH-VKEEDFVERLLIANTHDTLLCFSSHGKVYWLKVYELPMASRISRGKPIINVLPLA-NE
AINAMMPVREYKEGYSVFMATSKGTVKKVPLDAFSRPRSNGIIAIDLDEDDCLIGAGITDGSKDIMLFSDAGKVIRFDENLVRTMGRTARGVRGIRMGAQ
A-LISLVVVH--GTILTATEFGYGKRTAIEEYRVTGRGGQGVISIQVNE-RNGKVVRALQVDDNDEAMLITDKGTLVRFRVNELSIIGRNTQGVRLINVS
AGRVVGMQRIE-
>tr|A0A098GGJ6|A0A098GGJ6_TATMI DNA gyrase subunit A OS=Tatlockia micdadei GN=gyrA PE=3 SV=1
IEDLITEEDVVVTLSHQGYVKYQPLSAYQAQRRGGKGSATN-VKDEDFVERLIIANTHDTLLCFSNFGKLYWLKAYQLPLASRISRGKPIVNILPLA-NE
AINAMLPVREYQEGFFVFMATKHGTVKKVPLEAFSRPRSSGIIAIDLDEDDRLVGVDITDGTKDIMLFTDAGKVIRFDESLVRPMGRTARGVRGIRLGEQ
S-VISLVVAK--GTILTATENGYGKRTNIEEYRVSGRGGQGVISIQVNE-RNGKVVRALQVDDNDEAMLITDRGTLVRFKVDEISIIGRNTQGVRLINVN
QGYVVGMQRIE-
>tr|A0A078L1Q5|A0A078L1Q5_9GAMM DNA gyrase subunit A OS=Legionella massiliensis GN=gyrA PE=3 SV=1
IEDLITEEDVVVTLSHQGYVKYQPISAYQAQRRGGKGSATN-VKDEDFIERLVIANTHDTLLCFSNHGKLYWLKAYQLPLASRISRGKPIVNILPLA-DE
AINAMLPVREFNENYFVFMATKRGTVKKVSLEAFSRPRSTGIIAVDLDDDDRLVGVDITDGSKDIMLFTDAGKVIRFDENLVRPMGRTARGVRGIKMAAQ
S-VISLVVAQ--GTILTATENGYGKRTDVEEYRVSGRGGQGVISIQVTE-RNGKVVRALQVTDTDEAMLITDKGTLVRFRVGELSIIGRNTQGVRLINVA
SGHVVGMQRIE-
>tr|W6M8C4|W6M8C4_9GAMM DNA gyrase subunit A OS=Candidatus Competibacter denitrificans Run_A_D11 GN=gyrA PE=3 SV=1
LEDLITDETMVVTLSHAGYVKSQPLSLYRAQKRGGRGAATT-VREEDFVDKLFIASTHDTVLCFSNRGKVYWKKVYELPQAGRTARGKPIVNLLPLE-GE
RINAVLSVREFGDDHYVFFATTNGTVKKTPLSEYSRPRPSGIIAIDLRDGDQLVNVELTDGQRDVMLFSDAGKAVRFTETDVRDTGRSAYGVRGIRLGEQ
K-VIALIVVD-G-TVLTVTENGFGKRTPAAEYARHGRGGQGVIAIQTSE-RNGRVIGAVQVENDHEIMLISDGGTLVRTRVGEISVVGRNAQGVKLISLQ
GEKLAGVEKIE-
>tr|G9ENM0|G9ENM0_9GAMM DNA gyrase subunit A OS=Legionella drancourtii LLAP12 GN=gyrA PE=3 SV=1
IEDLITEENVVVTLSHQGYVKYQPLTAYQAQRRGGKGSATN-VKDEDFVSRLVIASTHDTLLCFSNHGKLYWLKAYQLPLASRISRGRPIINILPLA-GE
EINAMLPVREYQEGFYVFMATRNGTVKKVPLNAFSRPRSNGIIAVDLDENDRLVGVDITDGTRDIMLFTDAGKVIRFDESKVRPTGRTARGVRGIRIEEQ
A-VISLIVAH--GTILTATEHGYGKRTDIDEYRVSGRGGQGVISIQVTE-RNGKVVRSVQVNDSDEAMLITDKGTLVRFRVSELSIIGRNTQGVRLINVS
SGLVVGMQKIE-
>tr|A0A0B0H7X5|A0A0B0H7X5_SOVGS DNA gyrase subunit A OS=Solemya velum gill symbiont GN=gyrA PE=3 SV=1
TEDLIPEEDMVVTISHLGYAKSQPLADYQAQRRGGKGSATK-TKEEDFVDKLFVANTHDTILCFTSRGRVYWLKVYDLPQAGRTARGRPMNNLLPLE-DE
RVNAVLPVREYDENLFVFMATSSGVVKKTSLEAFSRPRASGIIAVELRDDDKLIGVDITDGSMDVMLFSTEGKAMRFSESQVRSMGRTATGVRGIKLGKH
Q-VTSLIIAR-GSRILSASENGYGKCTPVEDYPQKGRGGMGVISLKTSE-RNGKQVGAVIVDEDDEIMLITDGGTLVRTRVSDVSVTGRSAQGVKLISLS
AKHLIGIEPVV-
>tr|A0A0K1EIW4|A0A0K1EIW4_CHOCO DNA gyrase subunit A OS=Chondromyces crocatus GN=gyrA PE=3 SV=1
VEDLIQEEDMVVTVSHAGYVKRTSASIYRAQRRGGKGTLGMEA-EEDWVSQVFVASTHSHVFFFSDTGKVFVKKVYEIPQAARNAKGRAIVNFV-GEPGE
KVAAVMSVP---EGRFVVTVTRRGQIKKTALLEYENYRDKGIIGVRIEESDQLLVAA-TDGTQELVIATRTGMSIRFSE--VRATGRATMGVKAIELE--
-DVVGMGTSGDRDRVLAVCERGYGKQTPIEEFRKQSRGGKGVILI--SR--NGPVVGVAMVCTTDEVLLVTDKGQMIRTKVSEIRETSRNAQGVRLMNVD
-GRVVAIEAFA-
>tr|A0A0M0IT96|A0A0M0IT96_MORMO DNA gyrase subunit A OS=Morganella morganii GN=gyrA PE=3 SV=1
IEDLISQEDVVVTLSHQGYVKYQPLTDYEAQRRGGKGSAA-RIKEEDFIERLLVANTHDTILCFSNKGKLYWLKVYQLPEASRGARGRPIINILPLDENE
RITAIL--P--EEGKFVFMATASGTVKKTSLQDFSR-RNAGIIAVNLNEGDELIGVDLTDGSNEVMLFSADGKVVRFAEDAVRAMGRTATGVRGIRLS--
-DVVSLIIPRGEGEILTVTENGYGKRTAEAEYPTKSRATQGVISI--SE-RNGKVVGAIQVD-DDQIMMITDAGTLVRTRVSEVSIVGRNTQGVTLIRTG
-EKVVGLQRVA-
>tr|Q3IPV7|Q3IPV7_NATPD DNA gyrase subunit A OS=Natronomonas pharaonis (strain ATCC 35678 / DSM 2160) GN=gyrA PE=3 SV=1
REDLIAEEEVVVVVTEEDYVKRMPLSEFDPQHRGGKGIIGSRP-EGDRVSTVFTASTHDYLLCFTNQGQVYRLKVFELPEMGRTARGTSAVNVLDLNDGE
EITAVVN---I--EGYLAMATEAGYVKRTAVSEFENVHAGGIRAVSLEDDDSLVDVE-TDGDGDLLVGTKHGMTIRFDE--ARPMGRSARGVNGIKLE--
-DATGLVAASSDRDLLTVTKNGYGKRTPLSEYRRQSRYGKGLVDI--DR--NGPVCSLDAVSEDDGLVIMSESGQIMRTTVDEISTVGRNTKGVVVMSVD
-DRIAGIDVDS-
>tr|V4ZTU5|V4ZTU5_9ARCH DNA gyrase subunit A OS=uncultured archaeon A07HB70 GN=gyrA PE=3 SV=1
REDLIERRDDAVVVSEDDYIKRMPLSEFSPQRRGGKGIIGADL-QGDRVSSVFVANTHDYLLCFTTHGQVYQLKTYQVPEMGRTARGKSAVNVLDLDDGE
EMAAVVNTA----GGYLTMATRGGRVKRTSVDEFGNILSTGIRAISLEEGDELVDVEVTDGESDLVLATARGMTIRFDE--VRPMGRSARGVRGIRLE--
-SVVGVAAADEHDWLLTVTANGYGKRTDIDSYRRQSRNGKGLIDI--ND-RNGRACSIETVSQGDHVLVMSEAGQVIRTPVENISTVGRNTMGVTVMDLT
-DSVAAIEVVD-
>tr|M1XKV1|M1XKV1_NATM8 DNA gyrase subunit A OS=Natronomonas moolapensis (strain DSM 18674 / JCM 14361 / 8.8.11) GN=gyrA PE=3 SV=1
REDLIAEEEVVVAVSEDDYVKRMSLSEFDPQHRGGKGIIGSRP-SGDRVSTVFTASTHDYLLCFTNQGQVYRLKVFELPEMGRTARGTSAVNIVDLDDGE
EITAVVN---I--EGYFAMATRNGYVKRTEVSAFENVHSGGIRALTLESDDSLVDVE-TDDDGDLLVGTREGMTIRFSG--ARPMGRSARGVNGIDLR--
-DVAGLVAAAADRHLLTVTKNGYGKRTPLSEYRRQSRYGKGLIDI--DR--NGPVCSINAVSEGDGLVIMSESGQIMRTHVGEVSTVGRNTKGVVVMRLD
-DRVAGVDVVP-
>tr|M0H1V7|M0H1V7_9EURY DNA gyrase subunit A OS=Haloferax gibbonsii ATCC 33959 GN=gyrA PE=3 SV=1
RADLIPEEDVVVVVSEDDYIKRMPVSRFRAQHRGGKGIIGTDL-EGDNVSSVFVTNTHDDLLCFTNHGQVYQLKAYQVPEMSRTARGKSAVNLLDFDDGE
EITAVVN---LDIEGYLTMVTQNGYIKRTGTDRFQNILSTGIIATKLDEGDELVDVE-TDGESDLVIGTEQGMSIRFDE--VRAMGRSARGVRGVKLT--
-DVAGVAAIDEHSWILTVTENGYGKRTDLDAYRKQSRNGKGLIDI--NR--NGPVCAINTVGEGDHLVVMSDEGQILRTPVEDISTVGRNTMGVIVMDLD
-GDVASVDVIP-
>tr|E4NLL7|E4NLL7_HALBP DNA gyrase subunit A OS=Halogeometricum borinquense (strain ATCC 700274 / DSM 11551 / JCM 10706 / PR3) GN=gyrA PE=3 SV=1
HEDLIAEEDVVVVVTEDDYIKRMPLDTFRAQHRGGKGIIGTDL-EGDRVSSVFVASTHDYLLYFTNHGQVYKLKTYQIPEMSRTARGKSAVNLLELDDGE
EITAVVN---IETDKYLTMATQNGYVKRTSVEKFQNILTTGIIATKLDEDDELADVE-TDGSHDLVLASRDGMAIRFDE--VRAMGRSARGVRGMKLE--
-DLVGVAAVDEHNWVLTVTQNGYGKRSDIERYRRQSRNGKGLIDI--NR--NGPVCAMETVGYGDHLFVMSESGQILRTPVEDISTVGRNTMGVTVMDMD
-GHVASVDVYN-
>tr|E4T2N1|E4T2N1_PALPW DNA gyrase subunit A OS=Paludibacter propionicigenes (strain DSM 17365 / JCM 13257 / WB4) GN=gyrA PE=3 SV=1
PEDFYADDEMIITISHLGYIKRTALSEFRAQGRGGVGSKGSDS-DEDFIEYIYPASMHNTMLFFTSKGKCYWLKVYDIPEGSKNSKGRAIQNMLNIDNDD
KVNAFIRVKN--KSHYLIFATKNGVIKKTSLEAYSR-RQNGVNAITIREDDQVIQVRLTDGNSEVLMANRNGRAIRFH---VREMGRTATGVRGMTLDDG
-DLVGMICVNKNENIMVVSQQGYGKRTLLDVYRVTNRGGKGVKTMNITD-KTGKLVTIKNVT-ENDLMIINKSGITIRLKVADFRVMGRATQGVRLINLE
RNEIASVCKVL-
>tr|D7JDY7|D7JDY7_9BACT DNA gyrase subunit A OS=Bacteroidetes oral taxon 274 str. F0058 GN=gyrA PE=3 SV=1
PEDFYADDQMIITISHQGYIKRTALAEFKAQNRGGVGSKGGAT-DEDFIEYIYPATMHNYMLFFTQKGRCYWLKVYDIPEGSKTSKGRAVQNMLNIEADD
KINAFIRVKQ--SKHYLVFCTQNGIIKKTCLEAYSR-RQNGVNAITIRENDQVIQVRLTDGNSEIVIANRQGRAIRFH---VREMGRTATGVNAMAIDAN
-DVVGMVAVADTETVLVVSEKGYGKRSQLDIYRVTNRGGKGVKTMNITE-KTGKLVSIKLVD-SNDIMIINKSGMAIRMHVSDIRVMGRATQGVRLINLE
RNEIAAVCKVD-
>tr|F5REI4|F5REI4_METUF DNA gyrase subunit A OS=Methyloversatilis universalis (strain ATCC BAA-1314 / JCM 13912 / FAM5) GN=gyrA PE=3 SV=1
IEDLIAQQDMVVTLSHGGYFKRQPLADYRSQKRGGRGQAAA-VKDDDFVDQLFVANTHDYILCFSNRGRVYWLKVYEVPEGSRNSRGKPIVNLFPLL-GE
KITAVLPVKEF--NHYIFMATGRGTVKKTPLTDFSNPRKAGIIAVDLDEGDALIGVAITDGSDDIMLFSDAGKAVRFAE-DVRPMGRTARGVRGMMLE--
DGVICMLVSKNELSVLTATENGFGKRTRVTEYPKHGRGTKGVIAIQTSE-RNGGVVGAVLVETTDEIMLISTGGVLIRTRVADIREMGRSTQGVTLINLD
DGRLAGLEKVI-
>tr|A0A0K2G694|A0A0K2G694_9BACT DNA gyrase subunit A OS=Nitrospira moscoviensis GN=gyrA PE=3 SV=1
LEDLIAEEEVIVTITHTGYIKRNAVSLYRAQRRGGKGRIGMGI-EEDFVETLFTASTHDTLLFFTDAGKVYWLKVHEIPEAGRAAKGKALVNLLALSG-E
KVTATLPVK----DRFVVMATKKGLVKKTELSAYSN-RQGGIIALSLEGGDKLISVH-TDG-REILLGTKQGITIRFKE--VRPMGRTAYGVKGITLE--
NEVIGMETITPTTAILTVTEGGYGKRTPVGEYRVQGRGGKGIISVKTT-E-NGPAVGFLQVRG-DEIMLMAAQGKVLRCKVDDIREVGRNTQGVRVLDLE
EERVVGVARLA-
>tr|B2KAM8|B2KAM8_ELUMP DNA gyrase subunit A OS=Elusimicrobium minutum (strain Pei191) GN=gyrA PE=3 SV=1
MEDLIEEEDVVITLSNDGYAKRIPLDTYRTQNRGGKGVIGGKT-EEDFIEHLFVTSTHATILMFTTRGRVFSLRAYEIPEGNRLSKGKAIVNLLQISNEE
KITSAVAIE--SGETYLTMCTRFGLIKRVELGDFANIRKSGIIAIGLEDGDVLTSVQ-THGKSDLIIATRDGKAIRFDE--IRAMGRQAKGVRGIRLG--
-DVVGMEHALKGPDVLSVCENGYGKRTEFTEYRKQNRGGSGTITI--TR--NGKVVGIKLVDESKDLMVITENGMAVRIRCEEIRSVGRNAQGVRLVKLA
-SKIARIAPVI-
>tr|G2Z0N6|G2Z0N6_FLABF DNA gyrase subunit A OS=Flavobacterium branchiophilum (strain FL-15) GN=gyrA PE=3 SV=1
IEDLIADENVVITISHAGYIKRTNLSEYKTQNRGGVGQKSAGT-DQDFLEHMFVATNHQYMLFFTQKGKCFWMRVYEIPEGNKTAKGRAIQNLINIESDD
KVKAYICTQK--QNNYLIMVTKKGIMKKTLLEQYSR-RVNGVAAITIREDDELLAAELTNGESQILVAVKSGKLVRFE---TRPMGRTASGVRGITLQD-
-DVIGMVAVNDNSEILVVSENGYGKRSSL-DYRITNRGGKGVKTLNITD-KTGNLVSINSVT-ADDLMIINKSGLTIRLAVEDLRVMGRATQGVKLINLK
-KSIAAVTKVM-
>tr|A0A0P0U6S0|A0A0P0U6S0_FLAPS DNA gyrase subunit A OS=Flavobacterium psychrophilum GN=AMR72_03730 PE=4 SV=1
IEDLIADENVVITISHAGYIKRTPLSEYKTQNRGGVGQKGVAT-DQDYLEHLFVATNHNYMLFFTQKGKCFWMRVYEIPEGNKTSKGRAIQNLINIENDD
KVKAFICTQK--NSHYVIMATKKGIVKKTLLEQYSR-RLNGIAAITIREDDELLEAKLTTGESQVLIAVKSGKLVRFE---TRPMGRSASGVRGITLAD-
-DVIGMVSVNDNSEILVVSENGYGKRSSL-DYRITNRGGKGVKTLNITD-KTGKLVSINGVT-ADDLMIINKSGLTIRMMVSDLRVMGRATQGVRLINIK
-NSIAAVTKVV-
>tr|A0A095UYR2|A0A095UYR2_9FLAO DNA gyrase subunit A OS=Flavobacterium aquatile LMG 4008 GN=gyrA PE=3 SV=1
IEDLIADENVVITISHAGYIKRTSLTEYKTQNRGGVGQKSAAT-DQDFLEHLFVATNHNYLLIFTQKGKCYWMRVYEIPEGTKASKGRALQNLINIEPDD
KVKAFICTQK--KSHYVVMATKKGQVKKTSLEKYSK-RVNGVAAITIKEDDELLAAELTNGQSQILIAVKSGKLVRFE---TRPMGRTASGVRGITLRA-
-DVIGMVSVDEDTQLLVVTENGYGKRTKLEVYRITNRGGKGVKTLNITE-KTGALVSINTVT-ADDLMIINKSGLTIRMDVSTLRVMGRATQGVRLINIK
-NSIAAVTKVM-
>tr|A0A0E3TBP5|A0A0E3TBP5_FLAPS DNA gyrase subunit A OS=Flavobacterium psychrophilum GN=gyrA PE=3 SV=1
IEDLIADENVVITISHAGYIKRTNLNEYKTQNRGGVGQKSAGT-DADFLEHMYVATNHQYMMFFTQKGKCYWMRVYEIPEGSKTAKGRALQNLINIESDD
KVKAFICTQK--TSHNLIMVTKKGMVKKTSLDKYSK-RVNGVAAITIKEGDELLSAQLTDGNSQIIIAVKSGKLLRFE---TRPMGRTASGVRGIRLKE-
-DVIGLVSVNDNSEILVVAENGYGKRSSL-EYRITNRGGKGVKTLNITE-KTGQLISINTVT-ADDLMIINKSGLTIRMAVEDLRVMGRATQGVKLINLK
-KSIAAVTKVM-
>tr|K1XSI9|K1XSI9_9BACT DNA gyrase subunit A OS=uncultured bacterium (gcode 4) GN=gyrA PE=3 SV=1
MEDVIPDDATVIMITRDGYIKRLPPDTFRTQARGG-G--AMT--ED-AVENIISTTNHQNVMFLTSRGRVFRMKAYDVPEK-RTAKGQALVNFL-QGG-E
K--AILTAD---KYKYLVMVTSKGTIKKTDMTAFEN-R-SGLIAISLR--DDLEW---SD---DIFLVSSEGQSI------IRSMGRTASGVRGIRLKG-
-KIVGMDVVSKSAQLLIIMDNGYGKRTVI-EYK-QGRGGSGIKTA---TAKTGKI-SAHVVS-ERDMLVISQAGQVIRTPL-SIPV-GR---GVRIMRFK
E-TVASVALV--
>tr|A0A0G0MUT9|A0A0G0MUT9_9BACT DNA gyrase subunit A OS=Parcubacteria (Uhrbacteria) bacterium GW2011_GWF2_39_13 GN=gyrA PE=3 SV=1
IEDVVADTQTVVMITKAGYIKRIPPDTFKTQHRGG-G--TLT--DD-VVEQVFTTTTHKDLMFFTTRGRVFRLKAYDVPES-RTAKGQAIVNFL-QAG-E
T--ATFSME---KMKYLLMVTNKGTAKKVELDQFEN-R-SGLIVIKLN--DNLQW---TD---EVILVSRLGQAV------IRSMGRNASGVRGMKLKA-
-DIVGMDVVSHGAQLMVVMHNGYGKRSEL-EYK-QRRGGSGIKTA---SKKTGEV-SAYIIQ-DHDLFVVSEAGQVLRSPQ-SVPV-GR---GVRIMRFK
E-TVASVVLI--
>tr|A0A0G2AKL5|A0A0G2AKL5_9BACT DNA gyrase subunit A OS=Parcubacteria (Uhrbacteria) bacterium GW2011_GWA2_52_8d GN=gyrA PE=3 SV=1
IEDVVPDTQTVVMITKAGYIKRIPPDTFKTQHRGG-G--ALT--DD-VVEQVFTTTTHKDLMFFTNRGRVFRLKAYDVPES-RTSKGQAIVNFL-QAG-E
A--ASFSLE---NMKYLLMVTSQGTAKKVELDQFEN-R-SGLIAIKLV--DNLEW---TD---EVIMISQQGQAI------IRAMGRNASGVRGMKLKS-
-KIVGMDVVGAGDQLLVVMHQGYGKRSEL-EYK-QRRGGSGIQTA---TKKTGEV-SAYIVT-TRDLFVVSEAGQVLRATL-SVSV-GR---GVRVMRFK
E-TVARVALI--
>tr|A0A0G1SF76|A0A0G1SF76_9BACT DNA gyrase subunit A OS=Parcubacteria (Uhrbacteria) bacterium GW2011_GWE2_46_68 GN=gyrA PE=3 SV=1
IEDVIPDTPTMVMITKAGYIKRIPPDTFRQQKRGG-G--VLT--ED-AVEQLFSTTTHKDLLFFTSRGRVFQLKAYDVPES-RIAKGQALVNFL-QAG-E
T--AALSMD---TYKHLLMVTNKGTIKKTDISQFEN-R-SGLIAIKLR--DNLQW---TD---DIILVSQQGQAI------VRSMGRVAAGVRGMRLKG-
-AIVGMGVIREALELLVVMKNGYGKRTDI-EYK-QGRGGSGIKTA---TKKTGAV-AAHMLE-ERDLFAVSHAGQMIRSPI-SISV-GR---GVRIMRFK
E-TVASITLV--
>tr|A0A0G1MEE3|A0A0G1MEE3_9BACT DNA gyrase subunit A OS=Parcubacteria (Uhrbacteria) bacterium GW2011_GWF2_44_350 GN=gyrA PE=3 SV=1
MEDLIPDVPTVVMITRGGYIKRVPPDTFKTQTRGG-G--MLT--ED-EVEQMFSTTTHRDILFFTNRGRVFKIKAYDIPEA-RTAKGQALVNFL-NAG-E
L--SYLSFS---AYKFLFFVTGKGTVKKTAIEEFET-R-NGLIAIKLN--DNLEW---TD---DISLVTANGQSI------VRSMGRSAAGVRGIRLKG-
-AVVGMDVINTQAQLLVIMENGLGKRTPI-EYK-QGRGGSGIRTA---SAKTGKI-SARIVD-PQDIMVISTGGQVIRMSI-SVSV-GR---GVRVMRFK
E-KVASVTVV--
>tr|A0A0G0RW51|A0A0G0RW51_9BACT DNA gyrase subunit A OS=Parcubacteria (Uhrbacteria) bacterium GW2011_GWF2_40_263 GN=gyrA PE=3 SV=1
VEDVIPDTPTVVMITREGYIKRLSPDTFKQQKRGG-G--VVT--ED-VVEQVFSTTTHKDLLFFTTRGRVFSLKAYEVPES-RTAKGQALVNFL-QAG-E
Q--AALSMD---EEKYLLMVTTQGTIKKTEIASFEN-R-TGLIALKLK--DYLRW---TD---EIVLATAEGQAI------VRSMGRVASGVRGIRLKG-
-SVVGMGTIRSQIELLVVMKNGYGKRTDI-EYK-QGRGGSGIRTA---TKKTGKV-SARVIK-PRDLFVISEAGQVIRSSV-SVSI-GR---GVKIMRFK
E-TVASVELI--
>tr|Q114B8|Q114B8_TRIEI DNA topoisomerase (ATP-hydrolyzing) OS=Trichodesmium erythraeum (strain IMS101) GN=Tery_1901 PE=4 SV=1
EAAPPPTEKVVIEFSHRGYVRRIPAKGFEKYKIS-----I----ED-FTTNIIEATTDKTLVLLTRTGKAYPLKVNNIPSS-NRSKGVPLVTLLPPSI-T
-DAGQFILN--KENKDLIMLTQNGKIKRLCLSDLSD-R-RGVTVIKLK--DELRY---K----QVVLATSGGRLL------LPLMGRAAQGSQ-TRLR--
-QLVGCVTLDI--NLLLVSQHSYGKQIPV-ALR-ANRGGIGQNVF--TQD---DL-GIVASSL---VQVLTTDGRVFGMIA-RVKV-QQ---GHRLLKLG
K-KIIKVVGY--
>tr|U4KJI7|U4KJI7_9MOLU DNA gyrase subunit A OS=Acholeplasma palmae GN=gyrA PE=3 SV=1
NEDLIPVEDILITVTNNGYIKRMSLDNYKAQNRGGVGITGIKM-EDDYVEHMAMTQTHDYHLFFTNKGRVYKIKGYQIPVS-RQAKGLPIINLLPFEKDE
TLTSFTSVKD--QNQFLFFVTKKGIVKRTPVSDYKNIRTNGIIALTLREDDELLSVRPTNGNKDIILGASNGKAIRFN---VRSMGRTASGVKGMAID--
-DIVGIALV--DQEVLVVTENGFGKRTHVSEYRSQNRGGKGVKTLNVTE-KNGKLATLRAVT-DQDLIVSSDKGITIRTHIAQIAE-KRATQGVRIIKLR
-DKVATIALVP-
>tr|A0A0M1N0G6|A0A0M1N0G6_9MOLU DNA gyrase subunit A OS=Candidatus Phytoplasma pruni GN=gyrA PE=3 SV=1
NENLIAKERILITITNKGYIKRLNLDTYKKQNKGG-G--SMT--ND-FVEHFVVTSTHAYQLFFTNKGKVYQLKGHQIPST-RQSKGIPLINLI-PEG-E
F--AVTSVD--EIKDYLVLVTKKGLIKRNSIKEYEN-R-NGKIAFVLK--DEVLF---TQ---DIILAASDGRAI------IRKTTRMGSGVIGMRIKN-
-DIVGSAVVL-DQDILVVTELGYGKKTKV-EYR-QKRGGKGVKTL---TAKNGNV-SLQTIS--EELILISHLGQVIRISA-KISTKSK---GSSLLKLQ
D-KLIN-AVVV-
>tr|R4S1K4|R4S1K4_PHYAS DNA gyrase subunit A OS=Strawberry lethal yellows phytoplasma (CPA) str. NZSb11 GN=gyrA PE=3 SV=1
DEDLIEQKEIIITITNKGYIKVTDAEFYRQQKRGG-G--AMK--ED-FIEHLLFTSTHNFLLFFTNKGRVYQLKGYQINLD-KSSKGIPLVNLL-NKG-E
T--SCASVK--QPDNYLFFATKKGIVKKTSLKEYSN-R-NGKIAIVLR--DEVLT---TQ---NIILASNNGNAI------TRKTSRQSQGVIGMDLKK-
-ELIGAALFDPDQSILVMTEKGYGKITSV-QYR-QSRNGKGSKTI---NSKTGRI-ALKTAA--QDLIISSDKGQVIRVSI-DIKNKHK---GTKIIKLK
G-KAVL-VAVE-
>tr|Q9RP83|Q9RP83_ACHLA DNA gyrase subunit A OS=Acholeplasma laidlawii GN=gyrA PE=3 SV=1
NEDLIPVEDTVVTVTNNPYIKRMNLDEYKLQNRGGVGMSGVKL-DDDFVEHIAMTSTHDFHLFFTNLGRVFKLKGYTLPSS-RQSKGVPIVNYLNFQPGE
KLASFTTIKA--EDHYLNFVTKRGIVKRTHINNYKNIRQNGIIAISLREDDELLLTKSTNGHKHILLGASNGKAIHFL---IRQIGRTATGVRGMDIP--
-EIVGFAVV--EDDILVITENRYGKPTSITEYRLQNTGGKGVKTLNVTH-KNGKLKTLRKVT-DEDIIVVSHRGITIRMPIDQISQ-KRATQGVRIITLK
-DKVSTIAIVD-
>tr|U6E3R7|U6E3R7_9MOLU DNA gyrase subunit A OS=Candidatus Phytoplasma solani GN=gyrA PE=3 SV=1
DEDLIEEKTIVVTITNEGYIKSVDVDTYKQQKRGG-G--TIK--ED-LIEHCTTTSTHHYLLFFTNKGKVYQLKGYHIPLS-RTTKGTHLVNLI-AEG-E
F--SFTSVK--QEEEYLFFSTKKGIVKKTLLKEYRN-K-KGLIAIRLK--DEVLT---TC---GIVLASNNGNAI------TRKTSRNSMGVIGMCLGE-
-ELVGSALFDKDQSILVMTENGFGKITDV-QYR-QSRNGKGSKTI---SEEKGRI-TIKLVV--EELMISSDKGQVVRMSI-EIKKKNK---GTKIIKLK
G-KAVS-VASV-
>tr|B3R0L9|B3R0L9_PHYMT DNA gyrase subunit A OS=Phytoplasma mali (strain AT) GN=gyrA PE=3 SV=1
NESLINKETILITVTNKGYIKRLNLDTYKKQNRGG-G--SLK--ND-FLEHILITSTHDHQLFFTNKGKIYQLKGYEIPLS-RYSKGIPLVNLL-PEN-E
F--SLTSVK--EEKNYLVLVTKKGLIKRNSLKDFEN-R-NGKIAAVLK--DEVLF---TQ---DIILAASDGKAI------IRQTGRKSSGVRGIKIKT-
-EIIGMTVVD-KQNILVITEKGYGKITKA-EYR-QIRGGKGTKTL---TSRNGKV-RLLTIY--EELIIFSDHGKVVRIDT-QIPLKSK---GNILISLE
S-KVSS-VALI-
>tr|A0A0L0MJQ0|A0A0L0MJQ0_9MOLU DNA gyrase subunit A OS=Candidatus Phytoplasma phoenicium GN=gyrA PE=3 SV=1
NENLIEEERILITVTHKGYVKRLNLDIYKKQHKGG-G--NIT--DD-FVKHFVISTTHSYQLFFTNKGKVYQLKGYQIPFS-RQSKGIPLVNLIPL-G-E
F--SLTSVD--QANDCLVLITKKGLVKRNNIKEYEN-R-KGKIAFPLK--DEVLC---TQ---DIILAASNGRAI------IRKTTRQGVGVKGMNIDE-
-NVGAAVVSF-EQDILVLTEKGYGKKTKS-EYK-QKKGGKGQKTF---TSKNGQV-MLDTIL-NEEIILISDMGKVIRIEN-DVALKNK---GYRLFNLE
N-KVLAVVVPK-
>tr|M7P597|M7P597_PEWBP DNA gyrase subunit A OS=Peanut witches'-broom phytoplasma NTU2011 GN=gyrA PE=3 SV=1
KSSLIEKEKILITITHKGYIKRLNLDTYKKQNKGG-G--IIT--DD-FVEHFAITSTHDYQLFFTNKGKVYQIKGYEIASS-RHAKGIPLVNLIPM-G-E
F--TLTSVT--KNKDYLVLVTKKGFIKRNRIQEYAN-R-NGKIAFALK--DEVLA---TQ---DIILASSGGKSI------IRTTNRKSSGVIGMRMD--
-DVGAAVVCH-EQDILVVTEFGYGKKTQA-FYK-QQRGGKGVKTL---TDKKGHV-ALKTIF-NEELILISQCGQVIRIEA-KVSTKSK---GNRLFKLK
D-KLNLVVVQK-
>tr|U4KLW6|U4KLW6_9MOLU DNA gyrase subunit A OS=Acholeplasma brassicae GN=gyrA PE=3 SV=1
NEDLIPVEDVIITVTHNGYIKRMSVDEYKAQNRGGVGVTSIKM-DDDFVEHIQMTSTHDYHLFFTNTGRVYKIKGYEIPET-RQSKGLPIVNILPFEK-E
TLVTFTCIK--DEHKFLFFTTKKGIVKRTMVNEYQN-RTNGIIALGLKENDEVISVK-TDG-SHIILGATNGKAIRFDE--ARSMGRTASGVRGMSLG--
-DIIGMTSIHDNEEILVVTENGYGKRSYASEYRLQTRGGKGVKALNVT-D-NGKLKGLKSV-E-MDVIIVSDKGMVIRLHVLQISQTKRATQGVRLINLK
DQ-VVTLAAVP-
>tr|A0A061A854|A0A061A854_9MOLU DNA gyrase subunit A OS=Acholeplasma oculi GN=gyrA PE=3 SV=1
NEDLIPVEDIVVTVTNNGYIKRMNVDEYKLQNRGGVGMSGVKL-EDDYVEHILMTSTHDFHLFFTNKGRVFKLKGYKLPSS-RQSKGVPIVNFLTFQPGE
KLASFTSIRE--ENHYLFFVTKNGIVKRTHISNYQNIRQNGIIALNLKEDDELLVVKSTDGNKHILLGASNGKAIHFH---VREIGRTATGVRGMSLD--
-KIVGFAVI--EDDILIITEKGYGKRTSIQEYRLQNRGGKGVKTLNVTE-KNGKLSTLRKVT-DEDLIVVSDKGITIRMPINQISQ-KRATQGVRIISLK
-DKVATIAIVP-
>tr|A0A0B2A0Y2|A0A0B2A0Y2_9MICO DNA gyrase subunit A OS=Microbacterium mangrovi GN=gyrA PE=3 SV=1
IEDLIPEEEMVVTVTRDGYIKRTRSDNYRSQHRGGKGVKGA-QRADDVVEHFFVTTTHHWLLFFTNKGRVYRTKAYEVPEAGRDAKGQHVANLLALQPGE
EIAQILDIR---AT-YLVLATRGGLVKKTRLTEYDT-RQGGVIAIKLRATDEVVSAL--NEDDDLLLISRHGMSLRFTE--LRPMGRSTAGVKGMSFR-D
-DLLSASVATPGSSVFVVTEGGYAKRTDVDQYRTQSRGGIGIKVAKLN-D-RGVLAGGLIVQD-DEVLVVLASGKVVRSAVAEVPA-GRDTMGVVFARPD
-DRILAIARNT-
>tr|A0A0F0LTA4|A0A0F0LTA4_9MICO DNA gyrase subunit A OS=Microbacterium ginsengisoli GN=gyrA_1 PE=3 SV=1
IEDLIPEEEMVVTITRDGYIKRTRSDNYRSQHRGGKGVKGA-QRADDVVEHFFVTTTHHWLLFFTTKGRVYRAKGYEVPEAGRDAKGQHVANLLALQPDE
QVAQILDIR---SP-YLVLATRSGLVKKTRLGEYDT-RQGGVIAIKLREGDEVTSAL--DESDDVLLISRHGMSLRFTD--LRPMGRSTEGVKGMAFR-D
-DLLSASVVHDEGFVFVVTEGGYAKRTDVDQYRVQSRGGLGIKVAKLH-D-RGDLAGGLIVGD-DEVLVVLASGKVVRSAVAEVPA-GRDTMGVVFARPD
-DRILAIARNG-
>tr|A0A0Q8LPA0|A0A0Q8LPA0_9MICO DNA gyrase subunit A OS=Microbacterium sp. Root180 GN=ASD93_13425 PE=4 SV=1
NEDLIPEEEMVITVTRDGYIKRTRSDNYRSQHRGGKGVKGA-QRADDVVEHFFVTTTHHWLLFFTTKGRVYRAKAYEVPEAGRDAKGQHVANLLALQPGE
EIAQILDIR---AT-YLVLATRAGLVKKSRLTEYDT-RQGGIIAIKLRGDDELVSAL--DEGDDILLISRHGMSLRFSG--LRPMGRSTSGVKGMDFR-G
-DLLSASVAQDDEYVFVVTDGGYAKRTAVDQYRVQNRGGLGIKVAKLN-V-RGVLAGGLIVSD-DEVLVVLASGKVVRSAVAEVPA-GRDTMGVVFARAA
-ERIIAIARNG-
>tr|G4SWG5|G4SWG5_META2 DNA gyrase subunit A OS=Methylomicrobium alcaliphilum (strain DSM 19304 / NCIMB 14124 / VKM B-2133 / 20Z) GN=gyrA PE=3 SV=1
DEDLITEEDMVVTVSHEGYVKAQPLDDYKAQRRGGRGSATA-TKETDFIDKLIVANTHDTILCFSSLGKVYWLKVYQLPVASRASRGKPFVNLLPLE-GE
NINALLPVREFSADKFIFMATANGTVKKTPLPEFERQRTNGKIAIDLREEDALVGVAVTDGQQNILLFSTDGKAVCFNEEDVRSMGRTAAGVRGIRLQPQ
K-VISLIVSA-EGTVLTITENGYGKRTHLKEFVRKGRGGQGVISIQTSE-RNGNVVGAVLVSERDEIMLITNGGTLVRTRVDEISIVGRNTQGVTVIRLD
KNKVVGVDRIE-
>tr|G0A476|G0A476_METMM DNA gyrase subunit A OS=Methylomonas methanica (strain MC09) GN=gyrA PE=3 SV=1
AEDLITEEDMVVTMSHEGYVKTQPLTDYKAQRRGGRGSATA-TKENDFIDKLIIANTHDTILCFSSRGKVYWLKVYELPVASRASRGKPFVNLLPLE-GE
KINAMLSVREYSADKYVFMATASGTVKKTPLTEFAYQLAKGKIAIDLRDNDMLVGVALTDGQQNVMLFNSDGKAVCFNETDVRPMGRTAAGVRGMRLQEQ
K-IISLIIST-EGTVLNITENGYGKRTRIEEFTQHKRGGQGLIAIQTSE-RNGAVVGAVLVNDTDEIMLITNAGTLVRTRVNEISVVGRNTQGVTVIRLD
KGKVVGVDRIE-
>tr|H8GN71|H8GN71_METAL DNA gyrase subunit A OS=Methylomicrobium album BG8 GN=gyrA PE=3 SV=1
EEDLITEEDMVVTMSHAGYVKAQPLSDYKAQRRGGRGLATA-TKEEDFVDKLIVANSHDTILCFSSLGKAYWLKVYQLPIASRTSRGKPFVNLLPLE-GE
KINAMLPVREFSENKYIFMATTAGTVKKTPLIEFERQRTGGKIAIDLQEGDRLVGCAITDGSQNVLLFSSDGKAVCFNETDVRPMGRNAAGVRGMRLAEQ
Q-VISLIIGT-EGTVLNITENGYGKRTRLEEFPCHNRGGQGVIAIQTSA-RNGAVVGAVLVNAHDEIMLITDGGTLVRTPVDGISVLSRNTQGVTIIRLD
KKKVIGVDRIE-
>tr|R6VV14|R6VV14_9BACT DNA gyrase subunit A OS=Prevotella sp. CAG:474 GN=gyrA PE=3 SV=1
AEDFYPNDPVVITVSHLGYIKRTPLSDFREQARGGVGAKGAQT-DKDFIEYIYPATMHQTMLFFTKKGRCYWLKCYEIPEYDKSSKGRAIQNLLNIEPDD
AVNAFLRLRE--NSHYVVFATANGTVKKTCLEAYSR-RANGVNAIHITEGDEVVDVRLTNGHNELILANRNGRAVRFN---IRTMGRVSTGVRGMRLD--
-DVIGMIVVNDKESVMVVSENGYGKRSQVA-YRITNRGGKGVKTLAITE-KTGRLVAIKNVT-ENDLMIINKSGITIRLAVADVRIMGRATQGVRLINLA
KNIIASVCKVM-
>tr|A0A0C2JPL0|A0A0C2JPL0_9ACTN DNA gyrase subunit A OS=Streptomonospora alba GN=gyrA PE=3 SV=1
MEDFIAEDDVVVTITRGGYAKRTRLDGYRAQKRGGKGVRGA-QRQDDIVQHFFVTTTHNWILFFTNKGRVYRIKAYELPEAARDARGQHVANLMEFQPDE
EITQVMALR---AP-YLVLATRQGLVKKSRLEDFDS-RSAGIIAINLRD-DELISAR--FATDDLLLISGDAQAIRFPE--LRPMGRATSGVIGMRFQ-G
-ELLSMDVVREPADVLVATEGGYAKRTPADQYPVQNRGGKGVLTAKVV-ETRGRLVGALMVSEKDEVFAITSAGGVIRTHCSQVKQ-GRATMGVRLMNLD
-GQVVAVARNA-
>tr|A0A094PEW9|A0A094PEW9_9ACTN DNA gyrase subunit A OS=actinobacterium acAMD-5 GN=gyrA PE=3 SV=1
MADLIAERDVVITITRDGYAKRTMTDLYRSQRRGGKGIKGA-AREDDIVEHFLVTSSHDLLLFFTNKGRVYRAKGYEVPEAGRDAKGKHVANLLALTGDE
QIAQVLSIK---AK-YLVLATKSGLVKKTALSEFDT-RS-TLIAINLKE-DEVISAR--GKDEDLILVSAKGLSVRFNA--LRPMGRATSGVIGMRFK-D
-TLLAMDVVR-GAALVTVTDGGFAKRTSLTEWPAKGRGTMGMRAMRLV-EERGELVAALVCEN-DELFGIASNGIVIRTQVSEVRA-GRDTMGVSFMDLK
-GVVVAVAKLL-
>tr|A0A0N0TKB4|A0A0N0TKB4_9ACTN DNA gyrase subunit A OS=Nocardiopsis sp. NRRL B-16309 GN=gyrA PE=3 SV=1
MEDFIAEEDVVVTISRGGYAKRTRIDNYRAQKRGGKGVRGA-QKQDDIVQHFFVTTTHHWILCFTNQGRVYRTKAYELPEAARDARGQHVANLLPFQPGE
EIAQIMALR---AP-YMVLATREGLVKKSRLEDFDS-RAAGIIAINLRE-DELIAAR--FPDDDLLLISSDAQAIRFSE--LRPMGRATSGVIGMRFL-G
-DLLSMDVIRPSTDVLVTTENGYAKRTPSEQYPVQNRGGKGVLTAKVV-EARGKLVGALMVDEVDEVFAITSAGGVIRTGAEEVKQ-GRTTMGVRLMNLD
-GKIVAVARNA-
>tr|D6Y209|D6Y209_THEBD DNA gyrase subunit A OS=Thermobispora bispora (strain ATCC 19993 / DSM 43833 / CBS 139.67 / JCM 10125 / NBRC 14880 / R51) GN=gy
EEDLIAEEDVVVTITRGGYAKRTSIDAYRAQRRGGKGVRGA-QRQDDIVEHFFVTSTHHWLLAFTNKGRVYRFKAYELPEAARDARGQHLANLLAMQPDE
HVMEILSLR---AP-YLVLATRSGMVKKTRLAEYDS-RSGGLIAINLRD-DEVIAAR--SEEDDLLLVSKNAQAIRFKE--LRPMGRATAGVIGMRFA-G
-DLLAMEVIRDDEEVLVATEGGYAKRTPADQYPVQGRGGKGVLTAKIV-QSRGKLIGAIMVRE-DEVFAITSNGGVIRTRAAEIKR-GRQTMGVRLMHLS
-GSLVALARNA-
>tr|D2AVV1|D2AVV1_STRRD DNA gyrase subunit A OS=Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100) GN=gyrA PE=3 SV=1
IEDLLAEEDMVVTITRGGYAKRTNTDLYRAQKRGGKGVRGA-QRQDDIVDHFFVTTTHHWLLFFTNKGRVYRVKAYELPDSGRDARGQHLANLLAMQPDE
VVMEVLDLR---AP-YLVLATRSGLVKKTRLSEYDS-RSGGLIAINLRE-DEVIAAR--SEEDDLLLVSRGAQSIRFTE--LRPMGRATSGVIGMRFL-G
-DLLAMNRIGDD-DVLIATEGGYAKRTPADQYPVQGRGGKGVLTAKIV-SARGKLVGAAMVRE-DEVFAITSAGGVIRTSAGEIKQ-GRQTMGVRLMNLA
-GSVVALARNA-
>tr|A8LB22|A8LB22_FRASN DNA gyrase subunit A OS=Frankia sp. (strain EAN1pec) GN=gyrA PE=3 SV=1
VEDLIAREDVVVTVTRGGYAKRTKTDLYRSQKRGGKGVQGA-AREDDIVEHFFVTTTHHWLLFFTNKGRVYRAKAHELPEQARSAKGQHVANILAFSQDE
RIAEVMAIQ---AP-YLVLATKRGLCKKTALTDFDS-RAGGLVAINLRD-DELISAR--APGDDLLLVSRNAQSIRFHE--LRPMGRATSGVIGMRFD-A
-DLLSMDVVVPPADLLVATSGGYAKRTPLAEYPIQGRGGKGVLTAKIV-STRGGLVGALVVEN-DQLYAITSNGGVLRTVAKDVRR-QRQTMGVRLIDLE
-GQVVGVARNA-
>tr|D1ADA6|D1ADA6_THECD DNA gyrase subunit A OS=Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081) GN=gyrA PE=3 SV=1
YEDLIPEEDIVVTITRGGYAKRTRVDAYREQKRGGKGVRGA-QKQDDIVEHFFVTTTHHWLLFFTNKGRVYRAKAYELPEGGRDSRGQHVANMLAFQPEE
HIAEVLDLR---AP-YLVLATRQGKVKKTALKDFDS-RTGGIIAINLAE-DEVIAAR--FPTDDLLLVGTNAQAIRFHE--LRPMGRATSGVIGMRFD-G
-H-LDMHVIRDDEDVLVATEGGYAKRTPVEQYPVQGRGGKGVLTAKIV-QARGKLVGALMVRE-DGVFAMTSNGGVIRTNAGEIKR-GRQTMGVRLMNLA
-GSVVAIARNV-
>tr|A0A094Q2G2|A0A094Q2G2_9ZZZZ DNA gyrase subunit A OS=freshwater metagenome GN=GM50_11280 PE=3 SV=1
AEDLIPDQDVVVTITHGGYSKRTNADLYKSQRRGGRGVKGA-AKQDDIVDHFFVASTHDWLLFFTNEGRVYRAKVHELPDAGRDARGQHVANLLAFKPQE
QIAEVLWFK---VP-YLVLATKNGLVKKTALKEFDS-RSGGLIAISLKPGDEVVAAA--DKDDELLLVSKKAMSLRFTE--LRPMGRSTSGVIGMKFR--
-GLLSMSRINSQSFVFTATDGGYGKKTPVEEYRLQGRGGIGIKAAKID-ESRGSLVSALVISR-DEVLAITSAGTVMRTPAAEVRQ-GRDSMGVRLVNLD
-GSLLSVTRNG-
>tr|A0A094PL83|A0A094PL83_9ACTN DNA gyrase subunit A OS=actinobacterium acAMD-2 GN=gyrA PE=3 SV=1
AEDLIAEEDVVVTITRGGYAKRTKVDLYRSQKRGGKGVRGA-AKQDDIVEHFFTTTTHHWLLFFTNRGRVYRAKSYELPEAGRDARGQHVANLLEFQPDE
SIAQVLTLR---AP-YLVLATKNGKVKKTKLEEYDS-RSRGLIAINLQE-DEVIGAE--SPSDDLLLVSRKGMSVRFTA--LRPMGRATAGVTGMKFR-G
-DLLSMSVVTEGAFVFTVTDGGFAKRTPVEQYRVQNRSGLGIKAMKLV-DARGALAGALVVDT-DEVLAVTSNGGVIRSRVDEVNP-SRDTMGVRYMNLV
-GVVLGIARNA-
>tr|Q47U17|Q47U17_THEFY DNA gyrase subunit A OS=Thermobifida fusca (strain YX) GN=gyrA PE=3 SV=1
MEDFIAEEDIVVTITRGGYAKRTRLDNYRAQKRGGKGVRGA-QKQDDIVQHFFVTTTHHWILFFTNKGRVYRTKAYELPELARDSRGHHVANLVPFLPDE
EIAQVLALR---AP-YLVLATRSGLVKKTKLAEFDS-RSSGIIAINLRE-DELIAAR--YPTDDLLLISSNAQAIRFPD--LRPMGRATSGVIGMRFA-G
-DLLSMDVIREATDVLVATEGGYAKRTPADQYPVQKRGGKGVLTARIV-ESRGKLVGALMVDE-DEILAITSNGGVIRTKCAEIKQ-QRATMGVRLMHLS
-GHVVAIARNT-
>tr|B0VIP6|B0VIP6_CLOAI DNA gyrase subunit A OS=Cloacimonas acidaminovorans (strain Evry) GN=gyrA PE=3 SV=1
MEDLIADEMVVVTITHDGYVKRLPVDTYKVQARGGKGLSASNL-EEDFIQYLFVASTHSYILLFTDHGMCYWLKVFEIPEASRTARGKAIVNLVKLAEGD
RIKAFVT---FPE-QNIVMCTRNGLVKKTPLTAFSHPRSIGIKAIKLREGDELIDARCE-AGDDILLATHDGKCNRFSE--IRSMRRFSQGVKGIRLR--
-DVISMTIATASSTILAISEKGYGKRSPISSYSVTRRGSMGVITL--NR--NGYLAALMLVRDDDDLMIITQGGMIIRQRVSEISVVGRNTLGVRLINLA
-NVVRDISLVH-
>tr|T0LE70|T0LE70_9BACT DNA gyrase subunit A OS=candidate division Zixibacteria bacterium RBG-1 GN=gyrA PE=3 SV=1
LEDLIAEEDMVITITHSGYVKRLGVHAYRKQGRGGKGVIGIET-EEDFVEHLFIASTHDYILFFTNKGKCHWLKVHEIPQAGRAAKGKPIINLLELQE-E
KVKAYVPVK----KNFIIMATKNGIVKKSSLTAFSN-RRGGIIAIGIEEKDELIGAS-TDG-CDIVLATCEGQAVRFPE--VREMGRQAYGVKGITLE--
DFVIGMVVI--DSTLLSVTENGYGKRSPISDYRLTNRGGKGVINIKTT-D-NGKVVAIKEVLE-DELMLITQRGMIIRLPVKTIKVIGRNTQGVRLINLD
-GKVTDVARVI-
>tr|I3IHN2|I3IHN2_9BACT DNA gyrase subunit A OS=Candidatus Jettenia caeni GN=gyrA PE=3 SV=1
LEDLIAEENVAVIITHEGYIKRLPLTSYRKQHRGGKGVTGAEM-EGDFIEHLFVASTHDYILFFTDQGRVYWQKVYDIPQMGRTSKGRALINLL-EKEDE
NVTSLIPVR---ERQ-LVMATSNGIIKKTPLCAYGNPKKGGIIAITLDEGDKLICVK-TNGKQDIILGTEQGKAVRFSE--VRTMGRVTHGVKGITLK--
-DVRGMVIVDE-ASLLTVCEHGFGKRTDFGEYSAHHRGGQGVINI--TR--NGKVVALLDVRDEDELIMITAKGMVIRTSVNTVRAIGRNTQGVKLFSVV
-GKLVSVARVV-
>tr|Q1PZI6|Q1PZI6_9BACT DNA gyrase subunit A OS=Candidatus Kuenenia stuttgartiensis GN=gyrA PE=3 SV=1
REDLITEENVTVIISHEGYIKRLPLSAYRKQQRGGKGVIGAEM-EGDFAEHLFVASTHDYILFFTDQGKVYWLKVYDVPQMGKITKGRALINLL-EKEGE
NVTSFIPVR---DRQ-LVMATSHGIIKKTVLKAYGNPKKGGIIAINLDEGDTLIGVK-TNGKQDLILGTEQGKAVRFSE--VRSVGRVSRGVKGIKLK--
-DVCGMVVVDD-SSLMTICENGFGKRTNFEEYSAKNRGGQGVINI--TR--NGKVVGLLDVRETDELIMITKGGKIIRTPVNTIRIIGRNTQGVKLFDIG
-AKLISVARVI-
>tr|A0A0C9PEU9|A0A0C9PEU9_9BACT DNA gyrase subunit A OS=Candidatus Brocadia sinica JPN1 GN=gyrA PE=3 SV=1
IEDLIAEESNAVIITHEGYIKRLPLTSYRRQHRGGKGVAGADM-EGDFIEHLFVASTHDYILFFTDQGRVYWLKVYDIPQMARTSKGRALVNLL-EKEGE
KVTSLIPVR---ERQ-LVMATSNGIIKKTVLNAYGNPKKGGIIAINLDEGDKLIGVK-TNGKQDIILGTEQGKAMRFSE--VRTMGRVTHGVKGITLK--
-DVRDIVIVDE-ATLLTVCENGFGKRTDFAEYPVHHRGGQGVINI--TR--NGKVVALIDVRDEDELIMITARGQVIRTPVNTIRAIGRNTQGVTLFSIE
-GKLVSVARVV-
>tr|A0A0Q1A4G6|A0A0Q1A4G6_9BACT DNA gyrase subunit A OS=Candidatus Cloacimonas sp. SDB GN=APR54_12895 PE=4 SV=1
TEDMIADEEMVVTISHEGYIKRLPVDTYRKQGRGGKGLSGSNL-EEDFIENIFIASTHAYILFFTNLGKCHWLKVHKVPKVGRLARGKAIVNLL-QEREE
KIEAYVSVR---LPHYVTMVTKKGVVKKSELKAFSHPRINGIIAIKLMEGDQLIDAI-TEGNNDIILATSHGYANRFNE--VRSMGRNSQGVRGISLR--
-DVVAMVVVKR-GTLLAISENGYGKRSEISNYKKTRRGSKGVITL--TR--NGELIALIEVVDNDDLMIVTRAGMIIRQAVNKITVIGRNTQGVKLIELN
-DKVYDITRIP-
>tr|A0A0M6W6M3|A0A0M6W6M3_9ENTR DNA gyrase subunit A OS=Candidatus Providencia siddallii GN=gyrA PE=3 SV=1
IENLINQENVVVTLSHQGYVKYQPLSDYEAQRRGGKGSAAR-IKEKDFIEQLLVANTHDTIICFSNRGRLYWMKIYQLPESTRYSRGRPIVNLIPLE-NE
RITAILPVPEYKDGYYVFMATANGIVKKTALRDFGRPRSSGIVAVKLNDGDELIGVNLTNGVNEVMLFSAKGKVVRFAENTVRPMGRVSIGIRGIKLF--
LEVVSLIIPSN-GHILTVTEKGYGKRTEEIKYPIKSRATQGVISIKVSK-RNGNVIGAIQVDESDQIMIITDVGTLVRIRVSEVNVIGRNTQGVTLIKTA
ENKVVGLQKVN-
>tr|A0A084CMQ9|A0A084CMQ9_9GAMM DNA gyrase subunit A OS=Candidatus Photodesmus blepharus GN=gyrA PE=3 SV=1
MEKLIACEDIIATLSHAGYVKYQLLSDYESQRRGGKGSATK-MKEEDYIERLLIANTHDSILCFSTRGKAYRLKVYQLPLASRIARGKPIVNILPLE-NE
RITAILPVSKFNSEKFIFMSTNDGIVKKTPLDQFANVRSNGLIAINLHDGDLLINVDITNGESDVMLFSKMGKVVRFNEKKVRAMGRTAAGIRGIKLA--
DNVVSLIVPSN-GNILTVTQNGYGKRTELSEYPTKSRATQGVVSIKISE-RNGSVVGAVQVGENDEIMMITDAGTLVRTRVSEISQIARNTQGVTLIRTN
EDKVVALQRII-
>tr|A0A0M1JT38|A0A0M1JT38_9CYAN DNA topoisomerase (ATP-hydrolyzing) OS=Planktothricoides sp. SR001 GN=AM228_12645 PE=4 SV=1
LDVAFKPEDTVVEFTYRGYVKRFSPQNFERPKPAT-D--E----ID-DFSRQIYLRTDKTVVVFTRTGKAYPLNLRDLQLN-GRSRGTPLITLLPNSP-N
-IITQLLLS--TNATDLVLLTKRGRIKRISVEQISN-S-RGLTVVKLK--DELLS---K----FVILATSGGRLL------LPMMSYGTQAQQ-LRLG--
-QLVGFVTLNE--KFLLCTQDGWAKRMKV-SLR-ANPGDIGTQSL--KQT---DV-GIVPAVE---VILVTSQDRLLNLPM-AVKL-EK---GDRIKILQ
H-QIVSLNLSM-
>tr|A0A0P4UWD5|A0A0P4UWD5_9CYAN DNA gyrase subunit A OS=Leptolyngbya sp. NIES-2104 GN=NIES2104_36020 PE=4 SV=1
---EEEEQKAVVEVTQRGYVRRMVPKTYDRLSKNR-D--TTKE-DD-FATQTDFTTTGKTLVVFTRSGKAFAVKVRDIPQN-NGKKGTPLIALLPPAP--
---GTFILP--E-DQFVLLLTEQGRIKRLPLSEFTD-T-RGLTALKLK--DQLLC---Q----QVLLATSSGRVL------IPIATRTSQGQTGMRVS--
-KLVGWAIAN-DDTFLMISEQGYAKHMEV-ALR-ASAGELGTQSF--NKT---DV-GIVAVL-QSLVFLLTNENHLARIDV-DIDL-LK---GSRVVKLS
T-RVTHVSLPV-
>tr|Q83H53|Q83H53_TROWT DNA gyrase subunit A OS=Tropheryma whipplei (strain Twist) GN=gyrA1 PE=3 SV=1
IEDLIPVEPVVVVMTRCGYIKRTRIDQYRSQHRGGRGVKGA-QKADDVVLQFISTTTHNWLMFFTNTGRVYRAKAYEVPEASREARGQHVANLLPLKPNE
AVTRILSVS---EDTSLVLATKDGYVKKTTLKEYDT-LSTGVIAIKLRP-DKLVSAV--RSDQDIILVTKNARSLRFKG--LRPLSRGSYGVKGISLR--
-NLLSAELILSDSYIFVVSERGYAKRSRVGDYKLQARGGIGVRVANIT-E-KGVLADMLVVND-DEVLVILASGKVIRSSVAEVSP-LRYTTGVVFVRMS
-GKILAMTIAE-
>tr|A0A0Q8V1W2|A0A0Q8V1W2_9MICO DNA gyrase subunit A OS=Leifsonia sp. Root227 GN=ASE16_15695 PE=4 SV=1
MEDLIPEEEMVVTVTRGGYIKRTRSDNYRSQHRGGKGVKGA-QRGEDVVDHFFVTTTHHWLLFFSTKGRVYRAKAYELQEAGRDAKGQHVANLLAMQPDE
EIAEILDIP---AK-YLVLATRDGLIKKTALSEYDT-RSGGIIAIKLREEDELVSAL--EEDSDLLLVSRKGMSIRFTE--LRPMGRSTSGVIGMHFR-D
-DLLDASVVS-DGYVFVVTEGGYAKRTAADQYRLQNRGGLGIKVAKLS-D-RGDLVGALIVDD-DEVLVVLASGKVVRSSVAEVPA-GRDTMGVVFARFA
-SKIIALAKNT-
>tr|A0A0Q5JGG9|A0A0Q5JGG9_9MICO DNA gyrase subunit A OS=Agreia sp. Leaf335 GN=ASF79_14810 PE=4 SV=1
MEDLIPEEEMVVTVTRGGYIKRTRSDNYRSQHRGGKGVKGA-QRADDVVEHFFVTTTHHWLLFFTNRGRVYRAKAYELQEAGRDAKGQHVANLLAMAPDE
QIAQVLDIR---AK-YLVLATRGGLLKKTALDEYDT-RSGGIIAINLREGDELVSAL--EEDSDVLLVSKKGMSIRFTD--LRPMGRSTAGVIGMKFR-D
-DLLAASV-VSEGYVFVVTEGGFAKRTHVEQYRVQGRGGLGIKVAKLQ-E-RGDLAGSLIVED-DEVLVVLASGKVVRSAVAEVPA-GRDTMGVVFARFA
-ERIIALAKNT-
>tr|A0A0Q4BUF9|A0A0Q4BUF9_9MICO DNA gyrase subunit A OS=Plantibacter sp. Leaf1 GN=ASE44_13150 PE=4 SV=1
MEDLIPEEEMVITVTRGGYIKRTRSDNYRQQHRGGKGVKGA-QRADDVVDHFFVTTTHHWLLFFTTKGRVYRAKAYELQEAGRDAKGQHVANLLAMQPDE
EIAEILDIR---AT-YLVLATHDGLVKKTALSEYDT-RSGGIIAINLREGDELTSAL--ENDSDILLVSRKGMSIRFTE--LRPMGRATSGVIGMHFR-E
-DLLSASVLPSEAFVFVVTEGGFAKRTNIDQYRGQNRGGLGIKVAKLN-D-RGTLAGALIVDG-DEVLVVLASGKVVRSAVAEVPA-GRDTMGVVFARFA
-SRIIALAKNS-
>tr|V5C915|V5C915_9GAMM DNA gyrase subunit A OS=Methyloglobulus morosus KoM1 GN=gyrA PE=3 SV=1
DGDLITEEDMVVTKSHEGYVKAQPLSDYRAQRRGGRGSATA-TKEEDYVDKLIIANTHDTILCFSSRGKVYWLKVYQLPVASRASRGKPFVNLLALD-GE
KINAILPIKEFSDNKFIFMATSSGTVKKTPLNEFERQRANGKIAIDLREDDTLVGVAVTDGQQNVLLFASSGKANCFNESDVRPMGRTASGVRGMRLQD-
-QIISLII-GTEGMVLNITENGFGKRTRVEEFTQHKRGGQGMIAIQTSE-RNGALVGAVLVNEHDEIMLITDGGILVRTPVDGISVVGRNTQGVRIIRLD
TGKVIGVDRIE-
>tr|B9D3C2|B9D3C2_CAMRE DNA gyrase subunit A OS=Campylobacter rectus RM3267 GN=gyrA PE=3 SV=1
IEDLIPNENMVVTITHRGYIKRVPSKQYEKQKRGGKGVAVT-T-DDDFIESFFTSNTHDTLMFVTDRGQLYWLKVYKIPEGSRTAKGKAVVNLIQLQPDE
KIKAIIPTT---QSKSLAFFTKNGIVKRTNLSEFKNIRSIGVRAISLDENDELVTALVELIEKMLFIVTKKGMCLKFK---VRQMGRTARGVTGIKFKA-
-DVVGAAVIENAQEVLSVSQKGIGKRTTADEYRLTNRGGKGVICMKLT--RTGDLIG-VVVD-EQDLMALTSSGKMIRVDMQSIRKAGRNTSGVIVVNVD
--DVVSIAKCP-
>tr|A6Q294|A6Q294_NITSB DNA gyrase subunit A OS=Nitratiruptor sp. (strain SB155-2) GN=gyrA PE=3 SV=1
IEDLIPNEPMVVTITHRGYIKRVPLKQYEKQKRGGKGTAVT-T-EDDFIEDFFISNTHDTLMFVTDRGQLYWLKVYKIPEAGRTAKGKAVVNLLQLQPDE
KIKAIIPTT---EDKSLAFFTKNGIVKRTNLAEFSNIRSKGVRAITLDESDELVEAK----TKWLFIITKKGMCIRFP---VREMGRSARGVTGIRFKE-
-DVVGAETIAQEQELLTVSEKGIGKRTQASEYREQSRGGKGVIAMKLT--KTGDVVGVVT-E-NKDLMVLTSSGKMIRVDMESIRKAGRNTSGVMIVRLE
--KVVSIAKCP-
>tr|A0A0M2T123|A0A0M2T123_9GAMM DNA gyrase subunit A OS=Rheinheimera sp. IITR-13 GN=gyrA PE=3 SV=1
MEDLITEEDVVVTLSHLGYAKYQPLSDYEAQRRGGRGAAT-TVKDEDFVDQLLIASTHDTILCFSNRGRLYWMKVYQLPLASRQARGKPIVNLLPLE-NE
RITAIL--P--EEGKYVFMATANGTVKKTSLTEYSR-RSNGIIAVNLNEGDQLIGVDITDGNSQIMLFSDDGKVVRFNEDQVRPMGRGATGVRGIKLR--
-NVVSLIVPKSDGAILTVTENGYGKRTALQEYPEKSRATQGVVSI--SE-RNGLVVGAVQVN-LDEIMLISDKGTLVRTRVSEVSQVGRNTAGVILIRTI
-GKVVGVQRID-
>tr|I1DYS8|I1DYS8_9GAMM DNA gyrase subunit A OS=Rheinheimera nanhaiensis E407-8 GN=gyrA PE=3 SV=1
MEDLITEEDVVVTLSHLGYAKYQPLSDYEAQRRGGKGAAT-TVKDEDFVDKLLVASTHDTILCFSNRGRLYWMKVYQLPLASRTARGKPIVNLLPLE-GE
RINAIL--P--EENKYVFMATANGTVKKTSLTEYSR-RSNGIIAVNLNDGDRLIGVGITDGNSEIMLFSDDGKVVRFAEDQVRSMGRTATGVRGIKLR--
-GVVSLIIPNGSGPILTVTENGYGKRTALQEYPAKSRATQGVVSI--SE-RNGLVVGAVQVN-LDEIMMISNKGTLVRTRVNEVSEVGRNTQGVILIRTA
-NKVVGVEKID-
>tr|R4I011|R4I011_9ENTR DNA gyrase subunit A OS=Serratia symbiotica str. 'Cinara cedri' GN=gyrA PE=3 SV=1
IEDLINQEKVVVTLSYQGYVKYQSLSSYEVQRRGGKGSAA-RIKKEDFIDRLLVVNTHDTILCFSSLGRLYWMKVYQLPEVSCAARGRPIVNLLPLE-NE
RITAIL--P--EKGRYVFMATARGTVKKTALTDFSR-RSAGIIAVHLNAGDKLIGVDLTDGNNEVMLFSTSGKVVRFPENQVRSMGRTAIGVRGINLG--
-GVISLIVPRASGDILTVTQNGFGKRTAITAYPTKSRATQGVISI--SE-RNGQVVGAVQVE-IDQIMMITDAGTLVRTRVSEVSLVGRNTQGVRLIRTV
-ENVVGLQRVA-
>tr|M2Z6R3|M2Z6R3_9PSEU DNA gyrase subunit A OS=Amycolatopsis decaplanina DSM 44594 GN=gyrA PE=3 SV=1
VEDLIAVEDVVVTITRTGYAKRTKTDLYRSQKRGGKGVQGA-TKQDDIVQHFFVCSTHDWILFFTNKGRVYRAKAYDLPEANRNARGQHVANLLAFQPDE
QIAQVIEIP---AP-YLVLATRRGLVKKTKLTDFDS-RAGGLIAVNLRE-DELVGAV--AADDDLLLVSAEGQSIRFHE--LRPMGRATSGVLGMRFN-G
-DLLGINVVQPDKFLLVATGGGYAKRTPTEDYPVQGRGGKGVLTIQYD-QKRGRLVGAVIVDE-DELYAITSSGGVIRTSAGQVRK-GRQTKGVRLMNLD
-GTLLAVARNA-
>tr|A0A0F0GYL9|A0A0F0GYL9_NOCAE DNA gyrase subunit A OS=Lechevalieria aerocolonigenes GN=gyrA PE=3 SV=1
MEDLIAVEDVVVTITRTGYAKRTKTDLYRAQKRGGKGVQGA-QKQDDIVAHFFVCSTHDWILFFTNKGRVYRTKAYELPEANRNARGQHVANLLAFQPEE
EIAQVIQIK---SP-YLVLATRKGLVKKSKLSDFDS-RSGGLIGINLRE-DELVGAV--SADDDLLMVSADGQSIRFHD--LRPMGRATSGVQGMRFN-D
-DLLSVGVVQEGLFVLVATDGGYSKRTPIEDYPVQGRGGKGVLTIQHD-RRRGRLVGALIVDD-DELYAITSTGGVIRTRAEQVRK-GRQTKGVRLMNLG
-STLIAVARNA-
>tr|A0A0A2C638|A0A0A2C638_PROMR DNA gyrase subunit A OS=Prochlorococcus marinus str. PAC1 GN=gyrA PE=3 SV=1
DIDLIANERSVVLLTETGYLKRMPVNEFEATSRGTRGKAGTRS-GEEEVKKFISCNDHDSLLLFSDRGISYALPAYRVPQCSRTAKGTPIVQLLPIPREE
AITSLLSVS---DENYLLMLTRGGYIKRTPLSAFSKIRANGLIAIGLGDGDALTWVRLAESGDSVLIGSKNGMTIHFRL--LRPLGRSARGVKSMNLK--
-DLVSMDVLSTGPWVLVASGSGLGKRVPMTQFRLQKRAGMGLRAIKF--D-GDELVGLRVLG-GEELLLVSERGVIVRTSADKISQQSRAATGVRIQKLD
-GKLSEVVLVP-
>tr|A0A0G8AXH1|A0A0G8AXH1_9SYNE DNA gyrase subunit A OS=Candidatus Synechococcus spongiarum 142 GN=gyrA PE=3 SV=1
DIDLIANERSVVLLTSGGYLKRMPVREFVATNLGTRGKAGTRS-STEQVRLFISCNDHDTLLLFSDRGIVYALPAYKVPIASRTAKGSPIVQLLPISRQE
DITSLLALP---DDQHLLMLTQAGFIKRTPLSAFANIRVNGLIAIHLESGDALRWVRLAQVGDSVLIGSRSGMAIHVPI--LRSMGRTARGVRAMALR--
-DVIGMDVLVGVPWVLVASAHGRGKRVAMEEFPLQARAGMGRRALKF--P-GDALISLRILG-AEEVLLVSKQGVIVRLQADQISQQSRAATGVRLQKLG
-ERLAEVVLVP-
>tr|A0A076HG88|A0A076HG88_9SYNE DNA gyrase subunit A OS=Synechococcus sp. KORDI-52 GN=gyrA PE=3 SV=1
DIDLIANERSVVLLTETGYLKRMPVSEFEATSRGTRGKAGTRS-GEDAVKLFISCNDHDTLVLFSDRGVSYALPAYRVPQCSRAAKGTPVVQLLPIPREE
AITTLIPVS---DDTDLVMLTRGGFIKRTRLSAFSNIRSNGLIAINLEDGDALTWVRLAVPGDSVLIGSKAGMTIHFRL--LRPLGRTARGVRSMNLR--
-DLVSMDVLPVGPWVLVASASGLGKRVPVTQFRLQKRAGMGLRAMKF--D-ADELVGLSVLG-GEELLLVSEKGVIVRTSADAIPQQSRAATGVRLQKLD
-GRLLKVVLVP-
>tr|A0A0G0MY67|A0A0G0MY67_9BACT DNA gyrase subunit A OS=Peregrinibacteria bacterium GW2011_GWF2_39_17 GN=gyrA PE=3 SV=1
QKDTIPNMPILVMLSKEGYIKRILPNSFKQQHRGG-G--IMT--ED-EIRIMLYANNHDDLLYFTNRGRVFSLPVYEIPQS-RTAKGQAIVNLL-QQD-E
R--AILISN--ATRQFLFMGTNRGTVKKTAIEQFKN-R-TGLIAIKLR--DELEW---TD---TVVLVSREGKCI------VRSMGRTATGVRGMRLKG-
-DVIQMDVIRGNGDLLIVTQNGLGKRTAL-NYR-QGRGGSGVKTA---NPRTGKV-GAEVII-QGDLIIISKLGQIIRLPL-SIPT-GR---GVYLMRMK
S-IVASISIIR-
>tr|A0A0G0BK28|A0A0G0BK28_9BACT DNA gyrase subunit A OS=Peregrinibacteria bacterium GW2011_GWC2_33_13 GN=gyrA PE=3 SV=1
QKDTIPNEPMIIMLSEQNYIKRIPQAIFRSQNRGG-G--IVT--ED-EIKSILFAKNHDDILYFTNLGRVFTLPVFEIVEK-KMAKGQPIVNLL-KQD-E
K--AMFKIQ---YKKYLVMATIGGTVKKTEIEAFKN-R-NGLLAIKLK--DYLNW---SD---EVILVTKNGKCI------IRSMGRISMGVRGIKLKN-
-DVVEMEVSENESKLVVVTENGLGKSTEL-NYR-QRRGGSGIKTA---TAKTGPM-KAEIIH-EGDIIIISRQGQTIRLNL-DIPD-GR---GVYLMRMK
--KIASISIIN-
>tr|K2E3T7|K2E3T7_9BACT DNA gyrase subunit A OS=uncultured bacterium (gcode 4) GN=gyrA PE=3 SV=1
QKDTIPNSPMLVMLSQENYIKRVAPDSFRRQHRGG-G--IMT--ED-EIRILRYVNNHDDLLYFTNRGRVFKLPAYEIPQS-RTAKGQAIVNLL-QQD-E
W--AILKEE--SEGKYLFMGTNRGTVKKTPIEDFKN-R-TGLIAIKLR--DELEW---TD---NVVMITREGKCI------VRSMGRTATGVRGIRLKG-
-DVIQMDVIKGHGDLLVITEKGMGKRTPL-NYR-QGRGGSGVKTA---SPKTGKV-GAEVLE-EGDLIVVSKSGQIIRLPL-SIPN-GR---GVYLMRMN
N-KVASISIMK-
>tr|A0A0G0K1J4|A0A0G0K1J4_9BACT DNA gyrase subunit A OS=candidate division WS6 bacterium GW2011_GWA2_37_6 GN=gyrA PE=3 SV=1
EEDLVASEEVIVTVSEQGYIKRMKENVYSMQHRGG-G--KMT--GD-AVAHVFSCNTHDDILFFTNKGRVFLQKVYEIPEG-RGAKGQAIINLI-NDD-E
L--SILTKSILKDYKFLFFATKQGTIKKTALEDFLN-K-NGLIAIKLS--DELVW---TS---EVILVTKNARSI------VRETGRATMGVRGIRLKG-
-AVISMDVIRL-DFMLTVSENGFGKITKL-QYG-QGRGGQGIYAA---NAKTGKA-AARILD--MELLIMSEKGQAVKIPT-ELPQ-NR---GVKLMNIH
E-KVAALAVI--
>tr|R7IC49|R7IC49_9FIRM DNA gyrase subunit A OS=Faecalibacterium sp. CAG:74 GN=gyrA PE=3 SV=1
VEDLIQEEDMVVTLTRQGYVKRTPKSIYRAQNRGGRGVTGMTT-EEDFAVQMRVVSTHDEIMFFTNMGRVYMLKCYQIPEG-RTARGTAIINLIQIASDE
KVTCMVPVP---GEHNLVMATRDGMIKKTPYSEFAN-RKNGLIAINLKEGDELIGVD-TSG-DEILLGSRKGMAIRFSE--IRPMGRASMGVKSMRLD--
-DIIDMVPLE--ADVLAITTLGYGKRTNPDEYREQGRNGKGIIATKLT-D-TGDLAALLMVKD-EDLMLITDDGTIIRTRAEDIRVCGRNTQGVIVMKLQ
EGHVIAVARAE-
>tr|R5AHA5|R5AHA5_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:1024 GN=gyrA PE=3 SV=1
LDDIIQVEDMAVTMTHFGYIKRISPDTYRAQHRGGRGVKGQAT-EEDFVESLFVTCTHAPILFFTNMGRVYKIKCYAIPEG-RAAKGIPIVNLLQLQG-E
KVTATIPLP---EECYLVMATRDGVIKKTPMSEFDN-RKGGLIALNLREGDELMSVE-SNG-DEFIIATKKGKAVRFDE--VRAMGRTATGVRAITLE--
-GAVDMVKVVP-ATVLTVTEKGMGKRTEAEQYPMHRRGGKGVLAMMLT-D-TGDLTCLKMVKD-EDLMLIRDDGTIMRMPVSQVNVIGRNTQGVRLMRVD
GT-VVSIAVAP-
>tr|R6AWV9|R6AWV9_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:138 GN=gyrA PE=3 SV=1
MDDIIQEEDMVVTCTHHGYIKRIAEATYRTQRRGGVGISAGAT-EEDFLEDIFVTSTHSYIMFFTNKGRAFRIKCYSIPES-RTAKGTPIVNLLQLQTGE
FVTAAFPIG---EGGYLVLCTRQGVIKKTPLSDFSN-RKGGLIAQNLREGDELISVA-SAG-DEFIIGTRDGMSIRFSE--VRSMGRNASGVRAIKLS--
-GVVDMSMVK--SCVIAITENGMGKRTEEDAYRVQGRAGKGIIAMNIT-E-TGKLVCLKVSEN-EDLMLIRDDGVVIRVPVDTISVISRNTQGVRLMKID
EGRVASVALAP-
>tr|A0A084CL37|A0A084CL37_9GAMM DNA gyrase subunit A OS=Candidatus Photodesmus katoptron GN=gyrA PE=3 SV=1
MESLIARDDVVITLSHEGYVKYQLLRDYEPQRRGGKGSATR-MKEEDYIERLLVTNTHDSILCFSTRGKTYQLKVYQLPLASRIARGKPIINILPLE-QE
RITAILPVSQFNSNKFVFMATRNGIVKKTSLQKFSNVRSNGLIAINLHDDDLLIGVDITNGNSNAMLFSKFGKVVRFKEEKVREMGRAAAGIRGMKLV--
GNVVSLIVPAN-GNILTVTQNGYGKRTELFEYPIKGRATQGVVSIKISE-RNGSVVSAVQVEESDEVMIITNTGTLVRTRVSEISQVGRNTQGVILIRTT
EHNVVGLQC-I-
>tr|A0A0G1NXJ6|A0A0G1NXJ6_9BACT DNA gyrase subunit A OS=Microgenomates (Woesebacteria) bacterium GW2011_GWF1_46_13 GN=gyrA PE=3 SV=1
EEDLVPKEETLITVTKTGYIKRVPRGTYKAQRRGG-G--VMS--ED-EIEHLLSATTHDLVLFFTDKGRVFGTKAWEIPES-RQAKGQALVNLL-NEG-E
E--SILPLA--G--KHLMLVTASGIVKKTPISEYEN-R-SGLIAIRLR--DSLVS---TN---HVLILTKKGKAI------ARPMGRATSGVAGIKLE--
-TVIAMEVFPAFRDILTISEKGLGKRTPL-LFP-QKRSGKGVKAG---NDRTGNA-SAIMVT--EQVIITSKSGQLIKLPL-NIPQ-GR---GVILMRFA
K-SVAAAACLE-
>tr|K2B7C2|K2B7C2_9BACT DNA topoisomerase (ATP-hydrolyzing) (Fragment) OS=uncultured bacterium (gcode 4) GN=gyrA PE=4 SV=1
EEDLVAKEDVLITVTRTGYIKRVPRSTYKAQRRGG-G--V-MT-ED-EIELFASASTHDTLLFFTDRGRVFGNKVWEIPES-RQSKGQALVNFI-NED-E
Q--SIFPMN--S-KKYLIMATVKGVIKKTALEAYNN-R-NGLIAIKLT--DKLIS---T---DNVMLLSKMGKSI------VRPMGRATTGVRGIKLAS-
-GVIAMEVFPEYRDILTISQNGLGKRTRI-LFP-QRRGGKGVKAA---NSKTGNV-ADLI---VDQMVITSKYGQVIKLPA-NIPQ-GR---GVILMRFT
K-----------
>tr|A0A0G0QHP5|A0A0G0QHP5_9BACT DNA topoisomerase (ATP-hydrolyzing) OS=Microgenomates (Woesebacteria) bacterium GW2011_GWB1_40_101 GN=UT72_C0001G0001 PE=4 SV=1
EEDLVPKEETLITVTKTGYIKRLGLGTYRAQRRGG-G--LMT--ED-EIEHLISATTHDLILFFTNKGRVFGTKAWEIPES-RQAKGQALVNIL-NEG-E
E--SIIPLV----AKHLIMATKDGVIKKTQLSEFEN-R-SGLIAIRLR--DELVS---T---DHIMLLTKLGKSI------SRPMGRATSGVAGIKLE--
SDVIGMEVFPAFRDILTISEKGLGKRAPV-LFP-QKRSGKGVKAA---NEKTGPA-CAIMVT-VDQAVITSKFGQVIKLPL-NIPK-GR---GVILMRFA
K-SVAAIAVIE-
>tr|A0A0G0KAI5|A0A0G0KAI5_9BACT DNA gyrase subunit A OS=Microgenomates (Woesebacteria) bacterium GW2011_GWB1_38_5b GN=gyrA PE=3 SV=1
EEDLVPKEETLITVTKTGYIKRVPRNTYRAQHRGG-G--LMT--ED-EIDHIVGATTHDTILFFTDRGKVFGTRAWEINES-RQAKGQALVNII-NEG-E
M--SILAMD--A--MNLIMATSFGTIKKTDMKQFLN-R-NGLIAIKLD--DSLVT---TD---FVMLLSRNGKSI------VRPMGRATTGVRGILLE--
-KVIGMEVFPQFREVLTISENGMGKRTLL-NFP-QKRGGKGLKAT---TSKTGPA-SAIMVT--DQVVITSKYGQVIKLPL-NIPQ-GR---GVILMRFA
R-SVAAVTTLE-
>tr|F3Z751|F3Z751_9ACTN DNA gyrase subunit A OS=Streptomyces sp. Tu6071 GN=gyrA PE=3 SV=1
MEDLIAEEDIVVTISRSGYVKRTRTDDYRSQKRGGKGVRGA-KKEDDIVDHFFVTTTHHWLLFFTNKGRVYRAKAYELPDAGRDARGQHVANLLAFQPDE
SIAQILAIK---AP-YLVLATKGGLVKKTSLKDYDS-RSGGVIAINLREDDELIGAE--SADDDLLLISRKAQSIRFTD--LRPMGRATSGVKGMSFR-G
-DLLSMNVVRTGTFVFTATDGGYAKRSPVDEYRVQGRGGLGIKAAKIV-EDRGSLVGALVVET-DEILAITLGGGVIRTRVNEIRQ-GRDTMGVQLINLG
-RAVVAVARNA-
>tr|I5ATV9|I5ATV9_EUBCE DNA gyrase subunit A OS=[Eubacterium] cellulosolvens 6 GN=gyrA PE=3 SV=1
TEDLIPNDNNVLTMSHLGYIKRMSPENFHAQNRGGKGIKGTSN-ENDYIEDLFMTMSHDYIMFFTNLGRAYTLKAYEIPEASRTARGTAIINLLQLMP-E
KITAIIPVS---ENQYLFMATKKGMVKKTPVPAFRN-RKSGLAAITLRDDDDLIEVK-TDG-QDVFLATANGMSIRFNE--VRATGRGSMGVRGIWLD--
-EVIGMQLQAQGKYLLFSSENGIGKRTLFEEFRIQKRGGKGILCYKPN-E-TGKLVGVKAVNE-DELMLITVSGIVIRISVDDVSVIGRSAMGVKLMDVM
S--VASIAKVR-
>tr|A0A0R1XYB3|A0A0R1XYB3_9LACO DNA gyrase, A subunit OS=Lactobacillus composti DSM 18527 = JCM 14202 GN=FC83_GL001848 PE=4 SV=1
DEDLIEEEESAITLTHNGYIKRMPSSEFKTQNRGGRGIQGMGV-DDDFIEHLVITSTHDTVLFFTNHGKVYRSKGYEIPEYGRTAKGIPVINLLGV-DDE
RIQTMVHIP--NREHYLFFITRLGVVKRTLVGEFDN-RKSGLRAVTLRDEDELSNVL-TDG-ANILIGTHLGYAVSFRE--IRAMGRTAAGVRGIRLR--
-KVVGSDVLTPDKDVFVISEKGYGKRTPAKEYPIKGRGGKGIKTANIT-S-NGPLAGVTTVKN-EDILLMTNTGVLIRFEAENISTTGRATLGVRLIRVD
D-LVSTMAKVD-
>tr|A0A0R2CS97|A0A0R2CS97_9LACO DNA gyrase, A subunit OS=Lactobacillus rennini DSM 20253 GN=FC24_GL000235 PE=4 SV=1
DEDLIEEEDVVITLTHNGYIKRLPASEFKTQNRGGRGIQGMGV-DDDFIEHLVFTSTHDMLLFFTNTGKVYRAKGYEIPEYGRTAKGIPVINLLEI-KGE
RIQTVINVA---AEHYLMFTTRKGVTKRTAVAEFRN-RSNGLKAITLKDGDELMNVC-TDG-QNIIIGTHLGYAVSFAE--VRAMGRAATGVRGIRLR--
-HVVGAAILAPDSNVLVISENGYGKQTPATEYPIKGRGGKGIKTVNVT-A-NGPLAGLTTVAD-EDLMLITNTGIVIRFHVKDVSQTGRATLGVRLIRVD
D-KVATMTKVA-
>tr|W7UDB7|W7UDB7_RUMFL DNA gyrase subunit A OS=Ruminococcus flavefaciens 007c GN=gyrA PE=3 SV=1
IEDLIPEEDCVVTLTNNGYIKRMPLTEYKTQHRGGRGITGMKQ-EEDFVEEMFICGSHDNILFISNKGIMYKLKCYEVPDS-KASRGFNLINLLPLTENE
KIAAMMKTTN--DDKFITMVTKNGKIKRTNLSLYKNVRKNGLIAIGLDEGDEIAGVRMTDGNAQLFVATHNGMAIRLE---MRALSRSAHGVRAIKLR--
-YVVSMARV--GASLLTVTENGYGKKTDIESYRIQNRGGFGLTNYKVDE-IRGHVCGIKIVD-EDDIILVSSDGIIIRILASDIRI-GRIAKGVRVMRVN
-GNVVAFTRAE-
>tr|E6PCR5|E6PCR5_9ZZZZ DNA gyrase (Subunit A) OS=mine drainage metagenome GN=gyrA PE=3 SV=1
VEQLIPNTDVVVTYTDGGYIKRVSVDTFRTQNRGG-G--TISN-ED-VVRNFFATKTHDHVLFFTNKGRVYRLRAYEIPDT-RQARGTALVNLL-TPG-E
Q--ACFPID---GEKSLVMVTTHGVIKKTKLDEFAN-R-NGLNAINLD--DELLA---AR---DIILCTRAGMAV------VRAMGRNARGVKAMTLES-
-GIIAMDVIEDRKEVLLVTSQAFGKRTPI-DYR-TSRGGKGVKAF---REDIGRV-DQIMVA-DDQLLMITSGNQVIRINV-DIRR-GR---GVRLQRLG
G-EVIAITNLG-
>tr|W0U242|W0U242_9FIRM DNA gyrase subunit A OS=Ruminococcus bicirculans GN=gyrA PE=3 SV=1
IEDLIPVEESVVTYTNAGYIKRMPVSEYKAQKRGGRGVTGMKQ-EDDYIDELQTCSSHDNILFISNKGIMYKLKCYELPES-KASRGTNIVNLLELGEGE
KIAAMIKTA-F-EGKYIVMVTKNGKIKRTPLTSYRNVRKNGLIAIGLDEGDEIAGVRMTFGDNEVIVATHNGYAIRIR---IREMSRVAHGVKAIKLR--
-YVVSMARVR-GASVLTVAENGLGRRVPLESYKVQNRGGYGLMNYKSGG-----VCGIKVVD-D-DIIMISTDGIVIRIRACDISM-SRYSRGVRLMRVG
-DRVVSFTRTE-
>tr|R7KSU1|R7KSU1_9FIRM DNA gyrase subunit A OS=Ruminococcus sp. CAG:353 GN=gyrA PE=3 SV=1
VEDLIPVEDCVVTLTNIGYIKRQPISEYKTQKRGGKGVSAIKQ-DEDFIQEMFISSTHDDVLFITSKGIMYKLRCYEIAES-KQSRGVNVINMLPLAEDE
KIAAMIKTT-Y-DGKFLIMVTKNGKIKRTPLSAYKNVRKNGLRAVGLDDGDEIAGVRLTDGSAQVIVATRNGYAIRID---MRPMSRTAHGVKAIKLR--
-YVVSMARVR-GASVLTVTDKGLGRRVKLDDYRIQNRGGYGMLNYKVSD-DKGYVCGIKIVD-D-DIIMIATDGVIIRIRACDIRI-GRYATGVKLMRVS
-ERVVAFTRAE-
>tr|R6ZWH0|R6ZWH0_9FIRM DNA gyrase subunit A OS=Ruminococcus sp. CAG:379 GN=gyrA PE=3 SV=1
IEDLIPVEDSVVTYTHNGYIKRAPVDTYKTQKRGGKGVSGMKQ-EEDFVEELFIASTHDHLLFISNKGLMYRLKCYEITES-KASRGVNLVNLLPLAEGE
KIAAMLKTT-F-DDKFVVIVTKNGKIKRTPLSAYRNVRKNGLIAIGLDDGDEIAAVRMTDGSSQLMVATRNGMALRME---IRQMSRSAHGVRAIHLR--
-QVVSMARVR-GATVLTVTEQGFGRRTELDAYRLQNRGGYGLSNYKVDA-ERGFVCGIKVVD-D-DIILISSDGIIIRIRTSDIRI-SRYAKGVRVMRVS
-DKVVTFTRAE-
>tr|R7MQ06|R7MQ06_9FIRM DNA gyrase subunit A OS=Ruminococcus sp. CAG:624 GN=gyrA PE=3 SV=1
IEDLIPEEDCVVTLTNNGYIKRVSVDSYKAQRRGGRGVTGMKQ-EDDYVEEMFICGTHDNILFISNKGIMYKLKCYEIPDS-KASRGINLINLLPLTEGE
KIAAMLKAV-F-SGNYVIMVTKFGKIKRTELSMYKNVRKNGLIAIGLDEGDEIAGVRMTDGNAQLFVATHNGMAIRID---VRPMSRSAHGVKAIKLR--
-YVVSMARVR-GATLVTITENGFGKRCSLDAYKLQRRGGFGLKNYKVDE-ERGHVCGIKVVD-D-DIIMISSDGIIIRIRTSDIRI-GRIAKGVRVMRVR
-DKVVAFTRAE-
>tr|A0A0F5YKW8|A0A0F5YKW8_9CYAN DNA topoisomerase (ATP-hydrolyzing) OS=Limnoraphis robusta CS-951 GN=WN50_02845 PE=4 SV=1
QPLAPAEEETVLEFTHRGYVRRLPAKTVDSKSRSK-D--S-VT-DD-FIVSSYLTTTGQNLAILTRTGKAYPLNVGEIPTS-NRSRGTPLITLLPTSG--
FRSAPFIWA--D-KTDLILLTQQGKIKRLSLSEFLD-T-RGITIIKLK--DELGY---R----RVVLATSGGRLL------LPTMGRTAQGSQATRLR--
-QLVSCVTVS-KGSLLLVSQLGFAKRISM-RVR-TTRGSIGTQMF--RQR---DL-GMVSVN-NQQAYLLTNENRVLRFAI-ELRL-DQ---GDRLFELN
G-KIIGVRSGV-
>tr|U7QAM5|U7QAM5_9CYAN DNA topoisomerase (ATP-hydrolyzing) OS=Lyngbya aestuarii BL J GN=M595_5796 PE=4 SV=1
QPVAPAEEETFLEFTHRGYVRRLSPKTGDSKSRSK-D--S-IT-DD-FNVGRYLTKTGQNLAILTRTGKAYPLNVGDIPQS-SRSRGTPLITLLPPSP--
PMSAHFIVA--D-KTDLILVTQQGKIKRLSLKELSD-T-RGITIIKLK--DELGY---R----QMILATSGGRVL------LPPMGRTAQGSQVTRLR--
-QLVSCLTVP-KSSLLLVSELGFAKRISL-RVR-TTRGAIGTQMF--KPK---DL-GMVSVN-NQEAYLITSENRIVRFAV-EVKL-NE---GNRLFKLN
G-KIIGVRDPL-
>tr|K1VTF6|K1VTF6_ARTPT DNA topoisomerase (ATP-hydrolyzing) OS=Arthrospira platensis C1 GN=SPLC1_S370010 PE=4 SV=1
RPQLPAVEETLVEMTLKGYVRRVTPSALSRP--E-----I----DD-FPVASYLTTTAETLVIINRMGKAYPLSVADIPSS-Q--RGVPLITLLSPSA-S
-SRAAFAGASPSPETDLIMLSAEGKIKRFSGTDFMD-S-RGITVMKLK--DELSY---A----QVVLATSGGRLL------IPVMGRTAQGSV-TRLR--
-NLVGCITLSSNQFILLVSEQGYFKRISL-SLQ-SRRGGIGTQML--HRD---DC-GLAAISV---VYCLTSENRMVTLVP-VVPV-GK---GDRMVELN
G-RILSVVSPI-
>tr|H3NIJ4|H3NIJ4_9LACT DNA gyrase subunit A OS=Facklamia languida CCUG 37842 GN=gyrA PE=3 SV=1
DEDLIEEEDILLALTRTGYIKRMGEDEFHVQNRGGRGVKGMGL-DEDSIQCLVSASTHDSLLFFTNFGKVYRTKGYDIPQYGRASKGLPIVNLLNL-DGE
FVKEVVNSR--DKESYLTFVTKFGVVKRTAVKDYDN-RTNGLIAINLRPGDELINVL-TDG-QKILIASRQGYAVSFNE--IRVIGRSAAGVKGMTLR--
-EVIGAILLEADKQVLVVTENGYGKRTVIDQYAIRNRGGKGVKTANLS-A-SGQLVAVASVSA-DDLLIMTNEGIVIRIHAATISSSSRDTLGVKVIRLD
G-TVDKVVVIQ-
>tr|W1Q1D6|W1Q1D6_ABIDE DNA gyrase subunit A OS=Abiotrophia defectiva ATCC 49176 GN=gyrA PE=3 SV=1
DEDLIEEEDVLIALTSNGYIKRMTQDEFQVQNRGGRGVKGMGM-DNDNIQTLVSCSTHDSLLFFTNKGKVYQSKGYDIPEYGRTAKGIPVVNLLNI-EEE
YVKEIIVLH--DEDQYLFFVTKNGIVKRSDVSAYAN-RNNGLIALNMREDDELINVL-TNG-QNIIIGSHNGYAMTFAE--ARIMGRTATGVRGMKLR--
-GVVGAAVLNPESNVLVVTERGYGKQTPASEYAVKNRGGKGIKTSNIS-A-SGQLAGIVSTED-EDLMVMTDQGVVIRFNIASISVTSRATLGVKMIRLD
G-KVSSITKIM-
>tr|E4KME1|E4KME1_9LACT DNA gyrase subunit A OS=Eremococcus coleocola ACS-139-V-Col8 GN=gyrA PE=3 SV=1
DESLIEEEDVLIALTNKGYIKRMTQDEFSVQNRGGRGVKGMGL-DGDHIQTLVSCSTHDTLLFFTNQGKVYEKRGFEIPEYGRTAKGLPIINLIKI-DGE
EVKAMISIS--DHEKYLFFVTKTGTVKRTLSSEYYN-RNNGLIALNLKEDDSLVAVM-TDG-KPIIIGTHEGNAISFLE--VRAMGRTATGVRGVRLR--
-DVVGADIMVEGSDVLVITDKGYGKRTPVEQYSIKNRGGLGVKTSNIS-E-SGKLAGLLVVEH-EDILVMTNQGVAIRMKVEGISQSSRATLGVRMIRLD
E-VVSSITTIL-
>tr|K1LE72|K1LE72_9LACT DNA gyrase subunit A OS=Facklamia hominis CCUG 36813 GN=gyrA PE=3 SV=1
DEDLIDEEDILLMLTRTGYIKRVLEDEFRVQNRGGRGIKGMGV-EEDTIQCLVSTSTHDTLLFFTNYGKVYQAKGYDIPQYGRASKGLPLVNLLKL-DGE
QVLEIINVR--DKQRYLFFVTKNGRVKRTSVEEFYN-RVNGLIAMGLNEGDELRHVL-TDE-SNIILASHEGYAVSFDQ--VRVMGRPAAGVKGMSLR--
-GIIGADILKEDHQILVVSENGYGKKTPVEEYALRYRGGKGVKTAKIS-A-SGKLAAMLCIEH-EDLMIMTNTGIVIRICVKDISVSSRDTLGVKVIRLD
E-IVEKMVAIG-
>tr|R5CJU9|R5CJU9_9BACT DNA gyrase subunit A OS=Prevotella sp. CAG:1058 GN=gyrA PE=3 SV=1
PEDFYPNDPVVITISHLGYIKRTPLSEFREQARGGVGSKGAIS-DKDFTEYIYPATMHNTMMFFTKKGRCYWLKCYEIPEGAKNSKGRAIQNLLNIEADD
SIKAFLRLRC--NSHYVVFATKNGLIKKTSLEAYSR-RANGVIAINVLEGDEVVGVRLTNGHNELLLADRNGRAVRFD---VRAMGRVSTGVRGMKLD--
-DVVGMVVVNKTETIMVVSENGYGKRSQVE-YRVTNRGGKGVKTLNITE-KTGRLVAIKVVT-DNDLMIINKSGILIRLKVSECRIMGRATQGVRLINLA
KNVISSVCKVM-
>tr|A0A0G1E625|A0A0G1E625_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWA2_43_17 GN=gyrA PE=3 SV=1
TEDLIPNEQSIIMSTKDGYIKRLPTDTFKVQSRGG-G--IQT--ED-MVEFMFSAMTHADIMFFTSRGRLFQLKAYEIPQT-RTAKGQAIVNFL-QAE-E
K--AILSTE---NYKYLVMVTRQGLIKKVAIDKFQN-R-SGLIAIKLK--DALQW---SD---NVVLVSAQGQAI------VRAMGRGAAGVRGIKFKQ-
-KVVGMDILYQDEQLLVVMVNGYGKRTPL-EYK-QGRGGTGIKTA---TDKTGNE-SAFIVK-NEDLIIISDKGQVIRLPL-SVNV-GR---GVRLMRFK
A-NVASVTFI--
>tr|A0A0G0IQ07|A0A0G0IQ07_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWA2_38_13 GN=gyrA PE=3 SV=1
QEDLVPNEDIIVVITKDGYIKSLPPDTFRTQARGG-G--IFT--ED-VVEHFFTTTTHSNILFFTTRGRVYQLRGYDLPKS-RTSKGQAIVNFL-EMN-E
K--AALPLT--GDYKFLVMATKLGTIKKVDMNIFDN-R-SGLIAIKLK--DDLKW---SD---ETTLVTALGQSI------VRTMGRGAAGVRAVRLRK-
-DVVGMDIIDE--QLLIVTSKGYGKRTSL-QYK-QSRGGYGIKTA---TGKTGSI-TSMVVN-EEDLIIISIKGQVIRLPI-TISI-GR---GVRLMKFK
A-EVASITFI--
>tr|A0A0G1IUM9|A0A0G1IUM9_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWA2_44_12 GN=gyrA PE=3 SV=1
QEDLIPDEQTVVMVTQDGYIKSLQPEAFKLQGRGG-G--ILT--ED-MVDMLFSTRTHADILFFTSKGRVFQLKAYEIPQS-RTSRGKALVNFL-QTD-E
K--ALLPVS--SESAYLVMVTKNAVIKKVSISAFAK-R-SGLMAVKLK--DELRW---SD---HIILVTARGQAI------IRPMGRTASGVRGMRLKQ-
-DVVGMDIIDTKCYLMVVMEHGFGKRTQM-EYK-QGRGGSGIKTA---TTKTGRV-HARVVNGKGEFIIMSEHGQVIRLPF-SVNI-GR---GVRLMRFK
P-KVASVALV--
>tr|A0A0G0U3T8|A0A0G0U3T8_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWA2_40_23 GN=gyrA PE=3 SV=1
QEDLVPNEPTLIIITNDGYIKRLPIDTFKAQKRGG-G--ILT--ED-IVEQFFSTMTHNDLMFFTTMGRVFLLKAYDIPLS-RTAKGQALVNFL-QGA-E
K--TVLASD--AEVKNLVMVTEKGVIKKTPIEDFSN-R-SGLIAIKLK--DKLKW---TQ---EISLITDNGQSI------VRPMGRSASGVRGLRIKG-
-KIVGMGIIDSNLQILIITELGYGKLSEL-HYK-QNRGGSGVRTA---SSKTGKV-NGFVVD-DQDVIVISEKGQVIRLPF-SINV-GR---GVRLMRLR
A-KVASISLVQ-
>tr|A0A0G0MBJ1|A0A0G0MBJ1_9BACT DNA gyrase subunit A OS=Parcubacteria (Falkowbacteria) bacterium GW2011_GWE1_38_31 GN=gyrA PE=3 SV=1
VEDLVPNEEAVVMMTRDGYIKRMDPDTFKVQGRGG-G--ILT--ED-MIEFMFTTMTHTDLLFFTTRGRVFQLKAYEVPQQ-RTAKGQAIVNFL-QSG-E
K--SVLPLD---DAKYLFFATEKGLVKKVELKEFDN-R-SGLIAIKIR--DKLIW---TD---EIQLITAGGQAV------VREMGRTASGVHGIRLKG-
-SVIGMSVVNTKCQVLTIMEQGFGKRSAF-LYK-QGRGGSGIKTA---NSKTGKV-NAFVVN-DRDMIIISEKGQVIRLPF-SVNE-GR---GVRLMRFK
K-KVACVTWA--
>tr|I7JWM9|I7JWM9_9CORY DNA gyrase subunit A OS=Turicella otitidis ATCC 51513 GN=gyrA PE=3 SV=1
EEDLIARESVVATITSTGYAKRTKVDAYRSQKRGGKGVRGA-EKQDDVVRHFFVCSTHDWILFFTNFGRVYRLKAYELPEASRAARGQHVANLLEFQPNE
RIAQVIQIQ---AP-YLVLATAQGRVKKSRLDDYES-RSGGLIAINLNE-DELIGAA--SEKDDLLLVSEEGQAIRFTE--LRPMGRSTAGVKGMRFR-D
-DLLAMCVVC-GGYLLVATSGGYGKRTAMEDYHLQGRGGLGVMTFKYT-PKRGRLIGAIAVEE-DELFAITSAGGVIRTKANQIRP-SRATMGVRLVDLE
-DKLLAIDKNV-
>tr|A0A075TPM3|A0A075TPM3_9CORY DNA gyrase subunit A OS=Corynebacterium atypicum GN=gyrA PE=3 SV=1
EEDLIARENVVATITSTGYAKRTKVDAYRSQKRGGKGVRGA-EKQDDVVRHFFVCSTHDWLLFFTNFGRVYRLKAYELPEASRTARGQHVANLLEFQPEE
RIAQVIQIQ---AP-YLVLATAQGRVKKSRLADYES-RSGGLIAINLND-DRLIGVA--EEDDDLLLVSEEGQAIRFTE--LRPMGRATAGVKGMRFR-D
-DLLAMCVVR-GEYLLVATSGGYGKRTAMSEYSVQGRGGLGVVTFKYT-PKRGKLVGALAVDN-DEIFAITTSGGVIRTEVAQIRP-ARATMGVRLVDLD
-NQLFAIDKNV-
>tr|A0A0Q0UL55|A0A0Q0UL55_9CORY DNA gyrase subunit A OS=Corynebacterium sp. NML 130206 GN=gyrA PE=4 SV=1
EEDLIARENVVVTITSTGYAKRTKVDAYKSQKRGGKGVRGA-EKSDDVVRHFFVCSTHDWILFFTNFGRVYRLKAYELPEASRTARGQHVANLLELQPEE
RIAQVIQIQ---AP-FLVLATVQGRVKKSRLADYET-RAGGLIAINLGE-DRLIGAA--SEESELLLVSEEGQAIRFTE--LRPMGRATAGVKGMRFR-E
-DLLAMCVVR-GGSLLVATSGGYGKRTPIEEYNSQGRGGLGVVTFKYT-PKRGKLIGAMTVDD-DEIFAITSAGGVIRTEVAQIRP-SRATMGVRLVNLE
-DELFAIDRNV-
>tr|A0A0Q7PWI1|A0A0Q7PWI1_9ACTN DNA gyrase subunit A OS=Aeromicrobium sp. Root495 GN=ASD11_15615 PE=4 SV=1
MEDLIPDEEVVVTITKGGYAKRTRTDLYRVQNRGGKGVRGA-QRDGDFVEHLFPTTSHHWILFFTTAGRVYRTKAYQLPEAGRDAKGGHVAGLLSFQPDE
EIAQVLAIR---AP-YLVLATRKGLVKKTRLADYNS-RQAGVIAINFRD-DALIGAD--GPDDDLLLISRKAQAIRFRD--LRPMGRATSGVTGMKFR-D
-DLLSMTVIRRKLYVFTVTDGGFAKKTPIGDYRLQGRGGLGIKAMQIT-EARGELVGGLVLKT-DDVISVTSKGQVTRSVVEGVRA-GRGTMGVSFVKFK
-NHVVTIARNT-
>tr|A0A0Q4Z1Z3|A0A0Q4Z1Z3_9ACTN DNA gyrase subunit A OS=Aeromicrobium sp. Leaf272 GN=ASF38_04505 PE=4 SV=1
MEDLIPDEDVVVTITRGGYAKRTRTDLYRVQGRGG-G--RAQ--GD-FVEHLFPTTAHHWILFFTTAGRVYRTKAYQLPEG-RDAKGGHVAGLL-SQD-E
E--QVLAIR--EQAPYLVLATRKGLVKKTRLADYNS-R-AGVIAINFR--DALIG---A---DDLLLISKKAQAI-----QLRPMGRATSGVTGMKFR--
DDLLSMTVIR-EHADVAVEDV---------EDR-YVFTGLGIKAM---TENRGEV-GGLVLK-TDDVISVTASGQVTRSQV-GVPA-GR---GVTFVKFK
S-RVVTIARNT-
>tr|A0A0Q6VNI0|A0A0Q6VNI0_9ACTN DNA gyrase subunit A OS=Aeromicrobium sp. Root344 GN=ASC61_06980 PE=4 SV=1
DEDLIPDEEVVVTITKGGYAKRTKTDLYRVQNRGGKGVRGA-ARGDDLVEHMFATTSHHWILFFTTAGRVYRAKAYQLPEAGRDAKGGHVAGLLSFQPDE
EIAQVLAIR---AP-YLVLATKKGLVKKTRLGDYNS-RQAGVIAINFRD-DELIGAE--TPEDDLILISRKAQAIRFRE--LRPMGRATSGVTGMKFR-E
-DMLSMSVIRRQLYVFTVTDGGFAKKTPVEQYRLQGRGGLGIKAMQIT-ENRGELVGGLVLVT-DDVISVTATGQVTRSLVSGVNP-GRGTMGVSFVKFK
-DRVVTIARNT-
>tr|A0A0B2B1V0|A0A0B2B1V0_9ACTN DNA gyrase subunit A OS=Mumia flava GN=gyrA PE=3 SV=1
MEDLIPDEDVVVTITRGGYVKRTRTDLYRVQKRGGRGVRGA-TRGDDVVDHLFATTTHQWILFFTTAGRVYRAKAYQLPEAGRDAKGGHVAGLLQFQPDE
QIAQVLAIR---SP-YLVLATRNGLVKKTPLIEYNS-RQAGVIALNFRDDDALVGAE--SSDDDLILFSRKGQSIRFTE--LRPMGRATSGVTGMKFR--
-GLLSMRVIPPADYVFTATDGGYAKKTPVAQYRVQGRGGLGIKAMKLH-D-RGSLVGAVVVDD-DEIIAIKASGQVTRSRVADVSE-GRDTMGVKFVGVR
-DEVVALTRNE-
>tr|D0I6S4|D0I6S4_GRIHO DNA gyrase subunit A OS=Grimontia hollisae CIP 101886 GN=gyrA PE=3 SV=1
IEDLINQEDVVVTLSHEGYVKYQPLTDYEAQRRGGKGSAT-RMKEEDFIERLLVANTHDTILCFSTRGRMYWLKVYQLPLASRTARGKPIVNLLPLE-DE
RITAIL--P--EDDKFVFMATSDGTVKKTPLTDFSR-RSAGIIAVNLREGDSLIGVDITWGDNDVMLFSKSGKVVRFHE-QVRAMGRTAAGVRGIKLA--
-GVVSLIVPHNEGDVLTVTENGYGKRTELCEYPAKSRATQGVVSI--SE-RNGCVVGAVQVD-GYEFMMITNGGTLVRTRVAEVSQVGRNTQGVRLIRTS
-GRVVGLQRIE-
>tr|J3TWW9|J3TWW9_9ENTR DNA gyrase subunit A OS=secondary endosymbiont of Ctenarytaina eucalypti GN=gyrA PE=3 SV=1
IEDLINQEDVVVTLSHQGYVKYQPLTEYEAQRRGGKGSAA-SIKEEDFISRLLVANSHQTILLFSSRGRMYWMKVYQLPEASRGSRGRPIVNLLPLE-NE
RITAIL--P--EDGCHVFMATASGTVKKTSLIEFSR-RSAGIIAVKLNDGDELIGVDLTNGSNEVMLFSAYGKVVRFPENQVRSMGRTATGVRGISLA--
-GVVSLIVPHGNGSLLTVTQHGYGKRTAEVEYPTRSRATQGVISI--SK-RNGGVVGAVQVN-CDQIMMITDAGTLVRMRVSEVSIVGRNTQGVTLIRAP
-DSVVGLQRVV-
>sp|P14829|GYRA_KLEOX DNA gyrase subunit A OS=Klebsiella oxytoca GN=gyrA PE=3 SV=1
IEDLITQEDVVVTLSHEGYVKYQPVNDYEAQRRGGKGSAP-RIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQVPEASRGARGRPIVNLLPLE-NE
RYTAIL--P--EEGVNVFMATASGTVKKTPADEFSR-RSAGIIAVNLNEGDELIGVDLTSGQDEVMLFSAAGKVVRFKEDDVRAMGRTATGVRGIKLA--
-EVVSLIV---EGRILTATENGYRKRTAVAEYPTKSRATQGVISI--TE-RNGSVVGAVQVD-CDQIMMITDAGTLVRIRVSEVSIVGRNTQGVILIRTA
-DNVVALQR---
>tr|A0A0G4B741|A0A0G4B741_9BACT DNA gyrase subunit A OS=Microgenomates (Woesebacteria) bacterium GW2011_GWF1_31_35 GN=gyrA PE=3 SV=1
EEDLVAKEDVLVTVTKTGYIKRVPRNTYKAQRRGG-G--IMT--ED-EIDHLVTASTHDTILFFTNKGRVFGTKAFEIPES-RQAKGQALVNFL-NEG-E
E--SILPMS--A--KNLIMATSAGIIKKTELKEFEN-R-SGLIAIKLQ--DTLVS---TD---NVMLLTKKGMSI------VRPMGRATTGVTGVRID--
-KVIGMEVFPDFRDVLTLSIHGLGKRTRF-LFP-QKRAGKGVKAC---SAKTGEA-CAVMVT--DQLVITSKKGQVIKLPV-NIPQ-GR---GVIIMRFA
K-LIAAATVLE-
>tr|A0A0G0A271|A0A0G0A271_9BACT DNA gyrase subunit A OS=Microgenomates (Woesebacteria) bacterium GW2011_GWB1_33_22 GN=gyrA PE=3 SV=1
EEDLVAKEDVLVTVTRTGYIKRVSRNAYKAQRRGG-G--IMT--ED-EIDHLVTASTHDQILFFTNKGRVFGAKAYEIPES-RQAKGQALVNFL-NEG-E
D--SILPMD--SSAKNLILATASGIIKKTELKQFEN-R-NGLIAIKLQ--DSLIS---TD---NIMLLTQKGMSI------VRPMGRATTGVTGVKMTA-
-GVIGMEVFPEFRDILTLSIHGLGKRTRF-LFP-QKRAGKGVKAC---SAKTGDA-CASLVT-SDQLVITSKKGQVIKLPV-NIPQ-GR---GVIIMRFA
K-SIAAATVLE-
>tr|A0A0G0K3I3|A0A0G0K3I3_9BACT DNA gyrase subunit A OS=Microgenomates (Woesebacteria) bacterium GW2011_GWA1_37_8 GN=gyrA PE=3 SV=1
EADLIPKEETLITVTRTGYVKRLSPTTYKAQRRGG-G--MMT--ED-EIVHLVSATTHDTILFFTNKGRVFGTKAWDIGES-RQAKGQAIINLI-NDG-E
E--SIVPQS--G--THFIMATSKGIVKKTKVDEFIN-R-SGLIAIRLD--DTLVK---TD---HIILLTKKGKAI------VRPMGRATSGMKGIRID--
-SVIGMDVFSAFRDILTLSQNGLGKRTPV-LFP-QKRAGKGVKAA---NPKTGDA-AAYLVN--DQVIVTSKHGQIIKLPM-NIPQ-GR---GVIIMRFT
K-KVAAAACMF-
>tr|F2I195|F2I195_PELSM DNA gyrase subunit A OS=Pelagibacter sp. (strain IMCC9063) GN=gyrA PE=3 SV=1
VEDVIQEEKVIVTVTNKGYIKRTPLTSIRAQKRGGKGKTGIVTREEDFVSQLFPVSTLTPVLFFSSKGIVYRLKAWKIPEGSNTSKGKALANIFPIKADA
QISSILPLP---KDNFLIFVTANGKIRKNSILDFENIQANGKIAMKLEK-DKIVSVK-KKN-DDVMLNTYSGKSLRINK--IRIKGRSSKGIKGINLKN-
-DVISLTVLNHEEFILTITENGYGKRSSSYEFRESGRGGQGIINII---SRNGNIAASYSVK-DDDIMLITNKGQMIRCAVS-IRITGRNTQGVRIFKVE
-N-VVSSVCLT-
>tr|A0A0R2RKA1|A0A0R2RKA1_9PROT DNA gyrase subunit A OS=Pelagibacteraceae bacterium BACL5 MAG-121128-bin54 GN=ABS05_01470 PE=4 SV=1
IEETIQKESVIITVTLQGYIKRGSLDNVKQQKRGGKGKTGITTRDEDSVVQTLSVDTHTSVLFFSTEGLVYKVKAWKIPEGSSSSKGKSLFNILPLKNHQ
SISSIMPFP---KNYQIIFATSQGKIRKNSLEDFTSINASGKIAMKLDS-DKIIGVK-KDD-QDIMLSTKVGKCIRFEK--LRVKGRSSKGIRGIVLAN-
-DIVSLSIMDGEKFILSISQNGYGKKTPHIDYRVTNRGGKGIIGII---SRNGNVASSFPVF-GDEILISTNKGRVIRVAVK-IRTAGRNTQGVRIIKLS
-E-VVSAIKIV-
>tr|D0RNY7|D0RNY7_9PROT DNA gyrase subunit A OS=alpha proteobacterium HIMB114 GN=gyrA PE=3 SV=1
VEDVIQKEQVIVTVTNKGYIKRTPITNIKAQKRGGRGKIGIVTREEDFVTQLFSVNTLTPVLFFSNKGIVYKLKTWKIPEGSNQSKGKSLHNLLPIDNQS
YVSSIMPLP---SDLNIVFITKLGKIRKNNLEDFKNIQSNGKIAMKLDK-DEIVSVK-KAN-EDVMINSYNGKSLRVNK--IRLKGRSSKGVKGMNLKN-
-DVISLSILNPEEFILTITENGYGKRSSAYEFRETGRGGQGIINIS---TRNGNVAASFPIK-DDDIMLVTSKGQMIRVKVN-IRVAGRNTQGVRIFKTS
-D-VVTAVRLA-
>tr|Q1UZ45|Q1UZ45_PELUQ DNA gyrase subunit A OS=Candidatus Pelagibacter ubique HTCC1002 GN=gyrA PE=3 SV=1
IEETIQKESVIITVTLQGYIKRGALSSVKQQKRGGKGKSGITTRDEDSVVQTLSVNTHTSVLFFSTEGLVYKIKAWKIPEGSTTSKGKSLFNILPLKNHQ
SISSIMPFP---KNLQIVFATAKGKVRKNSLEDFSSINSAGKIAIKLDP-DKIVGVE-KDD-QDVMLSTKNGKCIRFEK--LRIKGRSSKGIKGIELSN-
-DIVSLSITNKGRFVLSITENGYGKKTLNNEYRVTNRGGKGIIGIV---SRNGSICSSFPVI-GDDVMISTNKGRVIRVAVK-IRTAGRNTQGVRIIKLS
-D-VVSAIKID-
>tr|W9E174|W9E174_PELUQ DNA gyrase subunit A OS=Candidatus Pelagibacter ubique HIMB083 GN=gyrA PE=3 SV=1
IEETIQKQSVIITVTLQGYIKRGSLDGVKKQKRGGKGKSGITTRDQDSVVQTLSVNTHTSVLFFSTEGLVYKIKAWKIPEGSSSSKGKSLFNILPLKSHQ
AISSIMPMP---KNYQIIFATAQGKVRKNSLEDFSLINASGKIAMKLDN-DKIVGVK-KDN-QDVILSTKFGKCIRFEK--LRVKGRSSKGIKGIELAN-
-DIVSLSVIDNEKFVLSISENGYGKKTSHSDYRVTNRGGKGIIGIV---SRNGNITSSFPVF-GDEILISTNKGRVIRVAVK-IRTAGRNTQGVRIIKLS
-E-VVSAIKID-
>tr|J9YU15|J9YU15_9PROT DNA gyrase subunit A OS=alpha proteobacterium HIMB5 GN=gyrA PE=3 SV=1
IEETIQKEAVFITVTLQGYIKRGSLNNVKQQKRGGKGKTGITTRQEDSVVQTLSVNTHTSVLFFSTEGLVYKIKAWKIPEGSSVSKGKSLFNILPLKNHQ
SISSIMPFP---KDLMIIFATAQGKVRKNSLEDFSSINASGKIAMKLDP-DRIVGVK-RDD-QDAMLSTKLGKCIRFEK--LRVKGRSSKGIRGIDLAD-
-DIVSLSIIQNEKFILSITENGYGKKTSHYDYRVTNRGGKGIIGIV---SRNGNIASSFPVY-GDDIIISTNKGRVIRVAVK-IRTAGRNTQGVRIIKLS
-D-VVSATKID-
>tr|A0A0J8YTV9|A0A0J8YTV9_9BACT DNA gyrase subunit A OS=bacteria symbiont BFo2 of Frankliniella occidentalis GN=gyrA PE=3 SV=1
IEDLINQEDVVVTLSHQGYVKYQPLSDYEAQRRGGKGSAA-RIKDEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLE-NE
RITAIL--P--AEGVNVFMATASGTVKKTALTDFSR-RSAGIIAINLRDDDSLIGVALTKGEDEAMLFSAAGKVVRFSEQAVRTMGRTAAGVRGIKLA--
-EVVSLII---EGAIMTVTENGFGKRTATQEYPTKSRATQGVISI--TE-RNGPVIGAVQVV-SDQIMMITDAGTLVRTRVSEVSIVGRNTQGVILIRTA
-DNVVGLQR---
>tr|D4G7N6|D4G7N6_RIEPU DNA gyrase subunit A OS=Riesia pediculicola (strain USDA) GN=gyrA PE=3 SV=1
QEDLIKKKKVIVILSNQGYIKFQSISDYDIQKRGGKGSST-RL-EKDFVKSVLVTDTHENILCVSNFGRIFSIKVYQLPESSRFSLGKPIVNFLSLKDGE
KITSIFSLK---KGNYILIATLMGLIKKISMDFLTKARKSGIIIINLNKRDEVIAMDSVKKRSEIILFTSSAKAIRFSE-SVRLTGRKSMGVMGVKIQ--
-ELVSMIIVEK---ILTITENGYGNRTKESEYLKKSRFIRGVSVIKNDE-RNGKIVGAIQVE-KDQVVIFTNYGILIRILVKDISVFKRNTKGIILIRKI
-DVVSGIYRVS-
>tr|W0DLU7|W0DLU7_9GAMM DNA gyrase subunit A OS=Thioalkalivibrio thiocyanoxidans ARh 4 GN=gyrA PE=3 SV=1
LADLIGEEDVVVTLSHAGYVKYQPLTAYRAQRRGGRGAATS-FREEDFIDRLLVANTHDTILCFSSRGRVYWIKVYELPQGSRVARGKPIVNLLPLE-DE
RINAILPVRGYAEDRFVFMVTAGGTVKKTPLTDFSRPRTAGIIAVDLREGDYLVDVALTDGSQEVMLVTSAGKAVRFPETDVRAMGRAACGVRGVRMDEH
R-VIALLIVG-EGSALFASEFGYGKRTGFDEFPVHRRGGQGVIAIQCAG-RNGMLIGAARVLDDQEVMLITDAGTLVRTAVAQIPLIGRNTQGVRLIRLS
EGKLAELARVE-
>tr|R9IZR6|R9IZR6_9FIRM DNA gyrase subunit A OS=Lachnospiraceae bacterium 3-1 GN=gyrA PE=3 SV=1
MEDLIPVSNTVITMTKLGYIKRMSVDNFRSQNRGGKGIKGMET-EDDYIEELLMTTTHHYLMFFTSTGKVYRMKAYEIPEAGRTARGTAIINLLQLQP-E
KITAVIPIK---DDHYLFMATKNGIVKKTPVTDYAN-RKKGLAAINLREEDELIEVK-TDN-KDMILVTRYGQCIRFHE--VRSTGRTSMGVIGMNLS--
-RVVGMQMNTQGEYLLIASEKGLGKLTRMDEFTPQNRGGKGVKCYKIT-E-TGNIVGVKAVNE-NEIMMITTEGIIIRMKVEGISVLGRVTSGVKLMNLD
-DTVASIAKVR-
>tr|R5HND0|R5HND0_9FIRM DNA topoisomerase (ATP-hydrolyzing) OS=Roseburia inulinivorans CAG:15 GN=BN501_00636 PE=4 SV=1
MEDLIPVTNTVIAMTKLGYIKRMSLDNFRAQNRGGKGIKGMET-DEDYIEELLMTTSHHYMMFFTNTGRVYRMKAYEIPEG-RTARGTAIINLLQLQPGE
KITAVIPIK-Y--GHYLFMATKNGIVKKTPITDYANVRKTGLAAITLREDDELIEVKKTDNEQDIFLVTKYGQCIRFN---VRSTGRTSMGVIGMNLT--
-KVVGMQMESQGESLMIVSEKGLGKCTLASEFT-QNRGGKGVKCYKITE-KTGNIVGVKAVN-DDEMMLITTEGIIIRIKVSDTA-LGRVTSGVKLMNLA
-DTVASIAKVR-
>tr|R7QWG4|R7QWG4_9FIRM DNA gyrase subunit A OS=Roseburia sp. CAG:182 GN=gyrA PE=3 SV=1
MEDLIPVTNTVITMTKLGYIKRMSVDNFRSQHRGGKGIKGMET-EDDYIEELLMTTSHHYLMFFTNMGKVYRMKAYEIPEAGRTARGTAIINLLQLQP-E
KITAVIPIR---EGNYLFMATKNGIVKKTPITDYAN-RKTGLAAINLRDDDQLIEVK-TDN-KDIILVTKFGQCIRFHE--VRSTGRTSMGVIGMNLT--
-GVVGMQMNTQGDALLIVSEKGLGKATLMTEFTPQNRGGKGVKCYKIT-E-TGNIIGIKAVND-SEIMLITTEGIIIRMKVEDISLLGRVTSGVKLINMD
-DTVASIAKVR-
>tr|N2AYB0|N2AYB0_9FIRM DNA gyrase subunit A OS=Eubacterium plexicaudatum ASF492 GN=gyrA PE=3 SV=1
MADMIPVTNTIITMTKLGYIKRMSMDNFRSQHRGGRGIKGMET-EDDYIEELLMTTSHHYLMFFTNMGRVYRMKGYEIPEAGRTSRGTAIINILQLQP-E
KITALIPIH---EGEYLFMATRKGIVKKTPILEYAN-RKTGLAAISLREDDELIEVK-TDN-KDIILVTKYGQCIRFNE--VRGTGRNSIGVIGMNLA--
-SVVAMQLDTQGEMLLAVSEKGMGKCTLMDEFTVQNRGGKGVKCYKIT-E-TGNIIGVKAVND-NEIMMITTEGIIIRMPVAGISVLSRVTSGVKLMNLE
-DKVASLTKVR-
>tr|R5TDJ7|R5TDJ7_9FIRM DNA gyrase subunit A OS=Roseburia sp. CAG:50 GN=gyrA PE=3 SV=1
MEDLIPVTNTVIAMTKLGYIKRMSADNFRAQHRGGRGIKGMET-DDDYIEELFMTTSHHYLMFFTNTGKVYRMKAYEIPEASRTARGTAIINLLQLAP-E
KITAVIPIK---DGWYLFMATKKGIVKKTAITDYAN-RKTGLAAITLREDDELIEVK-TDD-QDIFLVTKYGQCIRFHE--VRSTGRVSMGVIGMSLA--
-GVVGMQLNTQGEHLLIVSERGLGKRTSIDEFTAQNRGGKGVKCYKIT-E-TGNLVGVKAVND-NEIMIINTEGIIIRMKVSDISILGRVTSGVKLINME
-DTVASITKVK-
>tr|C5B7G2|C5B7G2_EDWI9 DNA gyrase subunit A OS=Edwardsiella ictaluri (strain 93-146) GN=gyrA PE=3 SV=1
IEDLIEQEDVVVTLSHQGYVKYQPLSDYEAQRRGGKGSAA-RIKEEDFIDRLLVANTHDTILCFSSRGRMYWMKVYQLPEASRGARGRPIINLLPLE-DE
RITAIL--P--AEGVNVFMATASGTVKKTALAEFSR-RAAGIIAVNLNDGDELIGVDLTDGNDEVMLFSAAGKVVRFKEDAVRAMGRTATGVRGIKLA--
-DVVSLIV---EGAILTVTQNGYGKRSSVAEYPTKSRATQGVISI--TE-RNGSVVGAVQVE-SDQIMMITDAGTLVRTRVSEVSIVGRNTQGVILIRTA
-DHVVGLQR---
>tr|A0A0R2SWW9|A0A0R2SWW9_9ACTN DNA gyrase subunit A (Fragment) OS=Actinobacteria bacterium BACL4 MAG-120920-bin41 GN=ABR72_01940 PE=4 SV=1
VEDLITEEDRVVTISKTGYAKTQPLSDYAAQRRGGMGAAAA-VKDEDLVEHLLVASTHDTLLCFTSRGKVYWLKVYMIPIASRTSRGKPLVNILPLE-EE
RVTSMLPIKEYTEDSFVFMATANGTVKKTPLPSFARQRSVGLRAIELDDNDELVGTAVTDGTRDLILMSTSGKTIRFSEQDVRAMGRTARGVRGIRLGAQ
R-MVSLMVAD-DKQVLTVSENGYGKRTKSSDFPLRGRGGQGVIGIQASD-RNGAVVGSVQVTDADEIMLISSKGTMVRTRVDEVSVQGRNTQ--------
------------
>tr|A0A0H5BX80|A0A0H5BX80_9ENTR DNA gyrase subunit A OS=Candidatus Westeberhardia cardiocondylae GN=gyrA PE=3 SV=1
TEDLINKKKVIVTLSNHGYVKYQPLTEYDAQKRGGKGSAAN-IKNKDFIHFLLVTNTHDTILLFSNQGKVYWMKVYQLPESNRTSRGRPIVNLLPLK-NE
KITTILPVKKYEEASHIFMATANGTVKKTSFNEFIHPRNTGLIAINLNKGDELIGVDLTNGNSDIMLFSSYGKVVRFSEKQVRNMGRKVIGVQGINLK--
KGVVSLIIPKN-SPILTITKNGYGKRTKQSEYPKKSRATQGVISIKVTK-RNGKVVSAVQADNSNQIMIITDAGTLVRIRVSEINIVSRNTQGVRLIRTI
DNHVVGLQRII-
>tr|A0A0J8H0J3|A0A0J8H0J3_9GAMM DNA gyrase subunit A OS=Gammaproteobacteria bacterium Q1 GN=gyrA PE=3 SV=1
MEDLIAEEDVVVTLSHEGYVKYQPLTEYEAQRRGGKGAAT-KMKDEDFIEKLLVANTHDTILCFSDRGRLYWLRVFQLPLATRTARGRPIVNLLPLE-NE
RISAIL--P--VDDKYIIMATANGTVKKTSLMEYSR-RANGIIALNLNDGDHVIGVDITNGDSEIMLFSNEGKVVRFSEQQVRSMGRTATGVRGMKFA--
-GVVSMIVPQGEGQVLTVTENGFGKRTPLLEYPAKSRATQGVVSI--SE-RNGAVVGAVQVN-NDEIMLISDKGTLVRTRVSEVSSVGRNTQGVRLIRTG
-NHVVGLQQID-
>tr|U3U9K1|U3U9K1_9ENTR DNA gyrase subunit A OS=Candidatus Pantoea carbekii GN=gyrA PE=3 SV=1
VEDLINQEDVIVTLSYHGYVKYQPLSDYEAQRRGGKGSAAR-IKEEDIIDCLLVANTHDSILCFSSRGRLYWMKVYQLPEASRSARGRPIVNLLPLD-NE
RITAILPVREYTKGFNILMSTAKGTVKKTALQEFSRPRSTGIIAINLHKNDELIGVALTNGSDEVMLFSAAGKVVRFSEATVRATGRLASGVRGIKLA--
ENVVSLIVPRA-GAILTVTQNGYGKRTINKAYPLKSRATQGVISIKVTK-RNGPVVGAVQVVDNDQIMMITNTGTLVRTRVSEVSIVGRNTQGVILIRTA
ENNVVGLQRVV-
>tr|F6DCK6|F6DCK6_THICA DNA gyrase subunit A OS=Thioalkalimicrobium cyclicum (strain DSM 14477 / JCM 11371 / ALM1) GN=gyrA PE=3 SV=1
EEDLIAVEERIVTLSQDGYIKTQPLSDYRAQKRGGRGSATA-MKEEDEVGQILVASTHDMLLCFSNRGKLYWKKTWQLPLAGRGARGKPIVNVFPLD-GE
SISSILPVSEFDEQHSVFMATKHAIVKRVKLIDFSRPRANGIIALDLLDGDELVGTALTNGEQDVMLFADGGKAIRFNENDVRVMGRQARGVRGMKLAE-
-QVMSMQIAQANTLILTATEHGFGKCTPVEDYSTINRGGQGVISIKTSE-RNGKVVSAVSVTTDQEVVLITNKGTLVRTRVAEISVVGRNTQGVKLINVG
KDWVVGIAVVN-
>tr|L8Y1F2|L8Y1F2_9GAMM DNA gyrase subunit A OS=Wohlfahrtiimonas chitiniclastica SH04 GN=gyrA PE=3 SV=1
ILDLIADEQVVVTLSHRGYIKYQQLGEYQAQKRGGRGSAAK-VKDEDHVVNLITTSTHAQLMCFSSIGRVYWLRTYELPEAGRGSSGRPIVNMLPLS-GE
RITSILPVEEYSAELFIVMATRHGVIKKTSLDKFASQRSTGVIALTLDEGDELIGTAITDGEKDIMLFTSDGKVNRFSEADVRDTGRGARGVKSMNLTD-
-QIISMIIPEADSVILIATENGYGKRTRAEEFTRHRRGGKGMIGIQTSE-RNGSVISACLVKEDEEVILISSNGVLVRTRVSEISILGRNTQGVRLIRLD
ESQLVGLTAVE-
>tr|Q31GD7|Q31GD7_THICR DNA gyrase subunit A OS=Thiomicrospira crunogena (strain XCL-2) GN=gyrA PE=3 SV=1
AEDLIAVENRIVTLSRDGYIKTQPLSDYQAQRRGGRGSATQ-MKEDDEIGQMIVASTHDMLLCFSNRGKLYWQKTWQLPLASRGSKGKPIVNVLPLE-GE
HITSILPVSEFSEGYYVFMATKQSTVKRVALSDFSRPRANGIIAVDLLDDDELVGTAITDGEQDIMLFSNIGKAIRFDENDVRVMGRQARGVRGMKLKD-
-MIISMQVARKDTLILTATEHGYGKCTPVDDYSTINRGGQGVISIKTSD-RNGNVVYSVAVTPDQEVVLITNKGTLVRTRVSEISVVGRNTQGVKLINVG
KGIVVGLAVVD-
>tr|A0A066ZMU7|A0A066ZMU7_HYDMR DNA gyrase subunit A OS=Hydrogenovibrio marinus GN=gyrA PE=3 SV=1
AEDLIAVEDRIVTLSQDGYIKTQPLSDYQAQRRGGRGSATQ-MKEDDEVGQLLVASTHDMLLCFSNRGRLYWQKTWQLPLASRGSKGKPIVNVFPLE-NE
HITSILPVSEFVEDKFVFMATKKSVVKRVSLTDFSRPRANGIIAVDLLEGDELVGTALTNGAQEIMLFSDVGKAIRFDENDVRVMGRQARGVRGMKLKD-
-VVISMQVAEPDTLILTATENGFGKCTPVEDYSTINRGGQGVISIKTSD-RNGNVVSAVSVKPEQEVVLITNKGTLVRTRVSEISVVGRNTQGVKLINVG
KGWVVGLAVVD-
>tr|A0A0K2DYS4|A0A0K2DYS4_PISSA DNA gyrase subunit A OS=Piscirickettsia salmonis GN=gyrA PE=3 SV=1
MEDLIADENMVVTLTHAGYVKTQTLDTYQAQRRGGRGSATS-MKDEDFIEQLVIASQHDTLLCFSNYGKLYWLKVYTVPQASRISKGRPIVNLLPLDKDE
KIQAMLPVREY--GMYIFMATAKGTVKKTALTEFSRPRVSGIISVDLVEGDRLVGVSLTHGECDMMLFTNSGKVIRFPETDVRAMGRNARGVKGINLTDQ
R-VISSVIAPIEGDILTVTENGFGKRTKIDEYRVQGRGGQGIISIQVSE-RNGTVVGAAAITHADEVMLLTNGGTLVRTRAEEISQVGRNTQGVKLINLA
NAKLVSVQPVV-
>sp|Q89AS3|GYRA_BUCBP DNA gyrase subunit A OS=Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp) GN=gyrA PE=3 SV=1
TSDLINKENVVITLSYSGYVKYQLLSSYEAQKRGGKGLAVK-TKEEDFIENLLVANTHDIILCFSSKGILYWMKVYQLPEASRHARGRPIVNLLPLS-NE
RITAILPISEYKDSINIFMATSKGMVKKTSLYEFKKPRTKGIIAINLKADDELIGVSLTNGNNTIMLFTAQGKAVHFSEILVRKTGRTAIGVQGIKIK--
KSVVSLVVPKK-GNILLITEHGYGKRTEIHEFPIKSRATQGTIAMKITK-KNGIVIGTMQVVNQDQIIIITNAGTLVRTRVLEIGILGRNTQGVIIIRTS
KKKVVALQKAN-
>tr|C5WC75|C5WC75_9ENTR DNA gyrase subunit A OS=Candidatus Ishikawaella capsulata Mpkobe GN=gyrA PE=3 SV=1
NEELIHHEDVVVTLSNQGYVKYQPLTDYEAQRRGGKGSAAQ-IKEEDFIDSLLVANTHDTILCFSSKGRLYWMKVYQLPEASRGSRGRPIVNLLPLA-KE
RITTILPVYKYEEGLNILMATAKGIVKKTAINEFSRPRNIGIIAIKLHGDDELIGVALTKGNDEIMLFSSAGKVVRFSETTVRNMGRAASGVCGIKLA--
KNVVSLIVPRK-GEILTVTQNGYGKRTANSEYPTKSRATQGVISIKVTK-RNGLVIGAIQVVDSDQIIIITNAGTLVRTRVSEVSIVGRNTQGVILIRTA
ENRVVGLQRVA-
>tr|A0A077JER2|A0A077JER2_9CYAN DNA gyrase subunit A OS=cyanobacterium endosymbiont of Epithemia turgida isolate EtSB Lake Yunoko GN=gyrA1 PE=3 SV=1
DTDLIANEQAIILLTEQGYIKRMPVSTFGSQSRATRGKAAAKI-ENDVVEHFLSCCDHNQVLFFSDRGVVYGIPAYQIPSASRTARGIPIVQMLPIPKDE
KITSILAVS---ENIYLIMLTRKGYIKKTALAAFSNIRANGLIAISLGEGDQLRWVRLARAEDSIIIGTRQGMAIHFHA--LRPLGRSTRGVKAMKLK--
-DFISMDILSSGPWVLAITNGGYGKRVPVNKFRLQNRAGMGVKAIKFK---TDRLASLHIVN-DNELMIVSNRGIVIRQAVNAISLQSRMATGVRVQRLD
-DAIAAVTLVS-
>tr|A0A086CID9|A0A086CID9_ATETH DNA gyrase subunit A OS=Candidatus Atelocyanobacterium thalassa isolate SIO64986 GN=gyrA PE=3 SV=1
DTDLIANEQAIILLTEHGYIKRMPVSSFDAQQRATRGKAAAKI-ENDVVEHFLTCCDHDVVLFFSDRGVVYATKAYQIPSSSRTSRGIPIIQMLSISKNE
KITSIIAVS---EDIFLVMLTCQGYIKKTALAAFRNIRTNGLIAISLEEGDQLRWVRLTREEDSIILGTRLGMAIHFHA--LRPLGRATRGVKSMKLK--
-DLISMDILLSGPWILAITNGGYGKRIPITQFRLQRRAGMGVRAIKFD---KDHLTSLRVVN-EDELMIVSNRGIIIRQVVKAISLQSRSATGVRVQRLD
-DAIAAVALVP-
>tr|T2JMV9|T2JMV9_CROWT DNA topoisomerase (ATP-hydrolyzing) (Fragment) OS=Crocosphaera watsonii WH 0402 GN=CWATWH0402_1685 PE=3 SV=1
DTDLIANEQAIILLTEQGYIKRMPVSTFEAQQRATRGKAAAKI-EDDVVEHFLTCCDHDQVLFFSDRGVVYAVNAYQIQAASRTARGIPIVQMLPIPKDE
KITSIVAVS---DDVFLVMLTRNGYIKKTALSAFSNIRTNGLIAISLGDGDQLRWVRLTREEDSIILGTSNGMSIHFQA--LRPLGRATRGVKAMKLK--
-ELISMDILTAGPWILAITNGGYGKRVPISQFRLQKRAGMGVRAIKF--D-SDCLASLRVVN-EDELMIVSNRGIIIRQAVDAISMQSRAATGVRVQRLD
-EAIAAVALVP-
>tr|B7JVT1|B7JVT1_CYAP8 DNA gyrase subunit A OS=Cyanothece sp. (strain PCC 8801) GN=gyrA PE=3 SV=1
DTDLIANEQAIILLTEQGYIKRMPVSTFGAQSRATRGKAAAKI-EDDVVEHFLSCCDHDHVLFFSDRGVVYTLPAYQIPAASRTARGVPIVQMLPIPKDE
KITSIVAVS---EDVYFIMLTRKGYIKKTALSAFSNIRTNGLIAIVLGEGDQLRWVKVAQEEDSIIIGTRLGMAIHFHA--IRPLGRSTRGVKAMKLK--
-ELISMDILSSGPWILTITNGGYGKRVPVKQFRLQNRAGLGVRVIKF--P-SDRLASLLVVN-EDELMIVSNRGIIIRQAVDAISTQSRMATGVRVQRLD
-DAIAAVALVP-
>tr|I2K672|I2K672_9PROT DNA gyrase subunit A OS=Sulfurovum sp. AR GN=gyrA PE=3 SV=1
IEDLIPNEPMVVTITHRGYIKRVPVKQYEKQHRGGKGIAVT-T-DDDFIEKFFTSNTHDTLMFVTDRGQLYWLKVYRIPEGSRTAKGKAVVNLINLQQDE
KIMAIIPTE---ADKGLVFFTQNGIVKRTNLSEYSNIRSNGVRAINLDENDALVDAK----TKWLFVATKKGLCIRFK---AREIGRVSRGVTAIKFKE-
-DVCGATTIENEDELLMISEKGLGKRTTASEYREQNRAGKGVISMKLT--KTGD-VVGVVVE-DKDLMCLTSIGKMIRVDMETIRKAGRNTSGVKIVNVD
--RVVSIAKCQ-
>tr|E6X3J4|E6X3J4_NITSE DNA gyrase subunit A OS=Nitratifractor salsuginis (strain DSM 16511 / JCM 12458 / E9I37-1) GN=gyrA PE=3 SV=1
IEDLIPNEPMVVTITHRGYIKRVPVKQYEKQRRGGKGTAVT-T-EDDFIERFFISNTHDTLMFVTDKGQLYWLKVYRIPEGSRTAKGKAVVNLINLDKDE
KIKAIIPTQ---EDKSLVFFTRNGIVKRTNLSEYSNIRSVGVRAINLDENDELIDAK----TKWLFVVTKKGMCIRFP---VREIGRVARGVTAIKFKD-
-DVCGATTIENEDEILIVSEKGMGKRTPASEYREQSRAGKGVIAMKLT--KTGDVVGVVF-E-DKDLMCLTSAGKMIRVDMQSIRRAGRATSGVKIVNVE
--RVVSIAKCP-
>tr|A0A0B0Q7Y0|A0A0B0Q7Y0_9PROT DNA gyrase subunit A OS=Sulfurospirillum sp. MES GN=gyrA PE=3 SV=1
VEDLIANEPMVVTITHRGYIKRVPLKQYEKQKRGGKGIAVT-T-DDDFIESFFVSDTHDTLMFVTDKGQLYWLKVYKIPEGSRTAKGKAVVNLIQLQAEE
KIMAIIPTT---ETKSLAFFTKNGIIKRTNLSEFKNIRSVGVRAITLDDDDNLVTAK----AQFLFIVTKKGMCIRFE---AREIGRTARGVTGIRFKE-
-DVVGAAVIYNQEELLTVTEKGIGKRTTAEEYRLQNRGGKGVIAMKLT--KTAD-LVGVVVD-DKDLMALSSSGKMIRVDMETIRKAGRNTSGVKVVSIE
--VVASIARCP-
>tr|C0VY08|C0VY08_9ACTO DNA gyrase subunit A OS=Actinomyces coleocanis DSM 15436 GN=gyrA PE=3 SV=1
DEDLIPEEEVVVTITRDGYAKRTRVDNYKAQHRGGKGVRGA-KRQDDVVEHFFVTTTHHWLLFFTNLGRVYRAKGYEIPEGGRDSRGQHVANLLAFQPDE
AISQVLAIR---AQ-YLVLATKSGLVKKTALADYNS-RSGGLIAINLREVDELVSAA--NAEDDLILVSCGGQSLRFNE--VRPMGRSTSGVRGMRFR--
-DLLTMEVIEHDSDLLVVTEGGFAKRSAIDTYPVRGRGGLGVKVANLV-E-RGGLVGALKVHE-DEVLVIMESGNIVRIPVAEISR-GRTTQGVTFARPN
-GRIIAVARNL-
>tr|A0A095Y2Q3|A0A095Y2Q3_9ACTO DNA gyrase subunit A OS=Actinomyces sp. S4-C9 GN=gyrA PE=3 SV=1
TEDLIPEEDVVVTITRDGFTKRTRVDSYKSQHRGGKGIRGA-KRQDDVVQHFFVTTTHHWLLFFTNLGRVYRVKAYEIPEGGRDSRGQHVANLLAFQPDE
EISDVLAIK---AD-YLVLATKSGLVKKTALQDYNS-RSGGLIAINLRDPDAVVSAK--NADQHLILISKMGQALRFEE--VRPMGRATSGVRGMKFR--
-GLLSLDVVHEGRDLLVITEGGFAKRSAIDTYPTRGRGGLGVKVANLV-D-RGDLVAGLEVTE-DEVLVIMESGNIVRSAVSEVPR-GRNTQGVTFARPS
-DRIIAITKNL-
>tr|A0A0A3ZKK8|A0A0A3ZKK8_DICCH DNA gyrase subunit A OS=Dickeya chrysanthemi GN=gyrA PE=3 SV=1
IEDLISEENVVVTLSHQGYVKYQPLSDYEAQRRGGKGSAA-RIKEEDFIDRLLVANTHDTILCFSSRGRLYWLKVYQLPEASRGARGRPIINLLPLE-DE
RITAIL--P--EEGMNVFMATASGTVKKTALTEFSR-RSAGIIAVNLNDGDELIGVDLTDGSNEVMLFSAEGKVVRFSESAVRTMGRTATGVRGINLQ--
-DVVSLIV---EGDILTVTQNGFGKRTAVTEYPVKSRATKGVISI--SE-RNGKVVGAVQVD-ADQIMMITDAGTLVRTRVSEVSIVGRNTQGVTLIRTA
-DRVVGLQR---
>tr|D9SF67|D9SF67_GALCS DNA gyrase subunit A OS=Gallionella capsiferriformans (strain ES-2) GN=gyrA PE=3 SV=1
MEDLIPPEDVVVTLSHGGYMKAQKMDDYQAQKRGGRGQATR-NKDDDFIDNLFVANTHNFILCFSNKGRVYWMKVYDVPQGSSGARGKPIVNLLPLE-GE
KINAILPVTEF--DKYVFFATANGTVKKTTLTDFSRPMKRGIIAINLDEDDYLIGVAITDGHHDVMLFSNSGKAVRFDE-DVRETGRASRGVRGMKLH--
ENVISMLVAENQQSVLTATENGYGKRTPVGEYTRHGRGTQGMIAIQTSE-RNGKVVAATLVNPEDEIMMIGTNGVLIRTRVREIREMGRTTQGVTLMNLE
KGRLAGLSRIA-
>tr|D5CTY4|D5CTY4_SIDLE DNA gyrase subunit A OS=Sideroxydans lithotrophicus (strain ES-1) GN=gyrA PE=3 SV=1
MEDLIAPEDVVVTMSHGGYMKAQKLDEYRAQKRGGRGQATA-TKEDDFIDNLFIANTHDYILCFSNRGRVYWLKVYDVPQGTRISRGKPIVNLLPLE-GE
KINAILPVKQF--DQFIFFATSEGTVKKTPLSDFANPRKAGIIAISLDEGDFLIGVAITDGKHDVMLFSDEGRAVRFDE-DVRGMGRTARGVRGMNLA--
KGVIALLVAENEQSVLTATENGYGKRTPISEYTRHGRGTQGMIAIQTSE-RNGKVVAATLVKPEDEIMLIGTSGVLIRTRVNEIREMGRATQGVTLMNVG
EGKLAGLSRIA-
>tr|A0A0E9M8N5|A0A0E9M8N5_9PROT DNA gyrase subunit A OS=Ferriphaselus amnicola GN=gyrA PE=3 SV=1
MEDMIASEDVVVTLSHAGYMKAQSLDEYRAQKRGGRGQAAS-TKEDDFVDNLFIANTHDYILCFTNRGRAYWLKVYEVPLGSRTSRGKPIVNMLALE-GE
KINAILPVREF--DKFIFFATAGGTVKKTALSQFGNPRKAGIIAIALDEGDFLIGVAVTDGKHDVMLFSDEGKAVRFDE-DVRPMGRDTRGVRGMNLA--
KGVIALLVAEDQQGVLTATENGYGKRTPIAEYTRHGRGTQGMIAIQTSE-RNGKVVAAALVNTEDEIMLIGTNGVLIRTRVREIREMSRATQGVTLINLE
AGKLAGLSRIA-
>tr|A0A0K2JT70|A0A0K2JT70_9MICC DNA gyrase subunit A OS=Kocuria palustris GN=gyrA PE=3 SV=1
MEDLIPQEDVVVTITRGGYVKRTRIDQYRAQRRGGKGIRGA-NRGDDVVEHFFTTTTHHWILFFTTHGRVYRTKAYELLEAGRDAKGQHVANVMAFQPGE
QIAQVMELS---AP-YLVLATRSGLVKKSRLEDYDT-RTAGVIAINLREGDELVSAK--DSDDDIFLVSRNGQSLHFQE--LRPMGRATSGVTGMKFR-D
-DLLAADVVAKESYVFVVTEGGYAKRTAIEQYRRQGRGGLGIKVAKVG-D-RGKLAGALIVGS-DEVMVVMASGKVVRSAVSEVPA-GRDTMGVIFAKPA
-KSIVGVAWNA-
>tr|Q47GP5|Q47GP5_DECAR DNA gyrase subunit A OS=Dechloromonas aromatica (strain RCB) GN=gyrA PE=3 SV=1
LEDLITPQDMVVTLSHGGYIKAQPLADYRAQRRGGRGQAAA-IKDEDFVDHLFMANTHDFILCFSNRGRCYWLKVYEAPQGSRVSRGKPIVNLFPLE-GE
RINAVLPVKEF--DKFIFMATRAGTVKKTPLSDFSNPRKAGIIAVDLLDDDYLIGVELTTGQSDIVLVSNAGKAVWFDE-DVRPMGRGARGVRGMKLQ--
AGVISLLVAESQQTVLVATENGFGKRTVLADFRHSGRGTQGVKAIADSE-RNGVVIGAKLVDDNDEVMLITTGGVLIRTRVSEIRGMGRATQGVTLISLD
DGKLAGLEKVA-
>tr|G8QHV8|G8QHV8_DECSP DNA gyrase subunit A OS=Dechlorosoma suillum (strain ATCC BAA-33 / DSM 13638 / PS) GN=gyrA PE=3 SV=1
IEDLITPQDMVVTLSHTGYIKSQPLADYRAQRRGGRGQAAA-MKDDDFVDHLFVANTHDYILCFSNRGRCYWLKVYEVPQGSRISRGKPIINMFPME-GE
QINAILPVKEF--DKYVFMCTVQGTVKKTSLANFSNPRKAGIIAVDLDEGDYLIGADLTTGQSDIVLVSDGGKAVWFGE-QVRPMGRQSRGVRGMMLQ--
EGVISLLVAESEETVLVATENGYGKRTRLGDFRRSSRGTQGVMAIAASE-RNGKIVAAKLVTDADEVMLITTGGVLIRTRVAEIRELGRATQGVTLISLD
AGKLSGLEKVA-
>tr|R7LF38|R7LF38_9BACT DNA gyrase subunit A OS=Prevotella sp. CAG:891 GN=gyrA PE=3 SV=1
PEDFYADDEVVITLSHLGYIKRTPLAEFKAQTRGGVGSKGGST-DSDFIEYIYPATMHNTMLFFTAKGRCYWLKVYELPEGAKNSKGRAIQNMLNIEPDD
SINACLHIRA--KTHFVLFCTKEGVIKKTCLSEYSR-RVNGVNAINIREEDRVVSVVLTNGTDEIVIANRNGRAIRFN---VRPMGRTATGVRGIRLD-G
-DVVGMICINDNETVMVVSENGYGKRSAVA-YRVTNRGGKGVKTLDITE-RTGPVIAIKAVT-DNDLMIINKSGIAIRMKLSEVRVQGRATQGVRLINLE
RNVISSVCKVP-
>tr|J9DB99|J9DB99_9ZZZZ DNA gyrase subunit A OS=gut metagenome GN=EVA_01722 PE=4 SV=1
PEDFYADDEVVITISHLGYIKRTPLAEFRAQSRGG-G--KGS--AD-FIEYIYPATMHNTMLFFTAKGRCYWLKVYELPEA-KNTKGRAIQNML-NDD-D
A--ACLHIRA-CRTHYVMFATKEGVIKKTCLTEYSR-R-NGVNAINIR--DRVVS---T---DEIIIANRNGRAI------VRTMGRVATGVRGIRLD--
-DVVGMICI--NETVMVVSENGYGKRSAV-DYR-TNRGGKGVKTL---TDKTGDV-AIKAVT-ENDLMIINKSGITIRMKL-EVRV-GR---GVRLINLE
R-DVISVCKVP-
>tr|R7P8L8|R7P8L8_9BACT DNA gyrase subunit A OS=Prevotella sp. CAG:617 GN=gyrA PE=3 SV=1
PEDFYPDDEVVITISHLGYIKRTPLAEFHAQSRGGIGSKGGST-ESDFIEYIYPATMHNTMLFFTAKGRCYWMKVYEIAEGTKNSKGRAIQNMLNIDRDD
SINACLHIKN--NSHYVIFCTKKGVIKKTCLSEYSR-RVNGVNAITIREDDKVISVCLSNGSDEIIIANKNGRAIRFN---VRTMGRTATGVRGMLLD-E
-DSIGMICVHNEESVMVVSEQGFGKRSKI-DYRKTNRGGKGVKTMSITE-KTGKLVAIKSVT-ENDLMIINKSGITIRLRVADVRVMGRATQGVKLINLE
RNSISSVCEVL-
>tr|R5GGF5|R5GGF5_9BACT DNA gyrase subunit A OS=Prevotella sp. CAG:755 GN=gyrA PE=3 SV=1
PEDFYADDEVVITISHLGYIKRTPLAEFRAQARGGVGSKGSSA-DADFIEYIYPATMHNTMLFFTAKGRCFWLKVYEIPEGTKNSKGRAIQNLLNIESDD
AINACLHIRG--ESHFVMFCTKNGVIKKTCLTEYSR-RTNGVNAITIREDDRVVSVCLTNGENEIILANRNGRAIRFA---VRTMGRTATGVRGMLLD-G
-DVVGMVCVNDQETVMVVSEKGYGKRSAVE-YRMTNRGGKGVKTLSITE-KTGKLVAIKIVT-DNDLMIINKSGITLRLKVADVRVMGRATQGVRLINLG
RNTISSVCHVS-
>tr|C9LDN5|C9LDN5_9BACT DNA gyrase subunit A OS=Alloprevotella tannerae ATCC 51259 GN=gyrA PE=3 SV=1
PEDFYADDEVIITISHLGYIKRTPLAEFRAQGRGGVGSRGGTT-DADFIEYIYPATMHNTMLFFTAKGRCYWLKVYELPEGAKNAKGRAIQNMLNIEADD
SVNAFLYIKN--KSHYVVFCTAEGIIKKTCLEEYSR-RTNGVKAITIREEDRVVSVVLTNGQDELVIANRNGRAIRFN---VRTMGRVSTGVRGIRLD-G
-DAVGMVCINDKETIMVVSDQGFGKRSAIE-YRKTNRGGKGVKTLQLTD-KTGKVAAIKSVT-DNDLMIINRSGITLRLKVADVRVMGRATQGVKLINLT
RNSISSVCVVT-
>tr|R5ZZ05|R5ZZ05_9BACT DNA gyrase subunit A OS=Prevotella sp. CAG:5226 GN=gyrA PE=3 SV=1
PEDFYADDEVVITISHLGYIKRTPLNEFRAQGRGGVGSKGGST-DSDFIEYIYHATMHNTMLFFTAKGRCYWLKVYELPEGAKNAKGRAIQNMLNIDPDD
SINACLHIRG--QSHFVMFCTKQGIIKKTCLSEYSR-RANGVNAINIREDDKVVSVVLTNGSDEIIIANRNGRAIRFN---VRAMGRTATGVRGMRLDAP
-DVIGMICINDKETVLVVSEKGKGKRSVVE-YRVTNRGGKGVKTLNITE-DTGKVVAIKAVT-EEDLMIINKSGITIRLRMDEISVQGRATQGNKLIDLK
RNVISSVCLVP-
>tr|L1MCU2|L1MCU2_9BACT DNA gyrase subunit A OS=Prevotella sp. oral taxon 473 str. F0040 GN=gyrA PE=3 SV=1
AEDFYADDEVVITISHLGYIKRTPLAEFRAQGRGG-G--KGS--QD-FIEYIYQATMHNTMLFFTAKGRCYWLRVYEIEET-RQSKGRAIQNML-NED-D
R--ACLHIR--CENHYVVFATQRGVVKKTRLTEYSR-R-NGVNAININ--DRVVS---TD---ELVMANKNGRAI------VRTMGRNATGVRGMLLDE-
-DIVGMVCVN-RESILVVSEQGYGKRSAI-DYR-TNRGGKGVRTL---TDKTGNV-AIKSVT--EDLMIINKSGITLRLRV-DIRL-GR---GVRLIDLK
R-DIISSVCQV-
>tr|A0A0E3Y9N3|A0A0E3Y9N3_9ENTR DNA gyrase subunit A OS=Blochmannia endosymbiont of Camponotus (Colobopsis) obliquus GN=gyrA PE=3 SV=1
IEDLINQENVVVTLSYQGYVKCQPLTDYEAQRRGGKGLAAR-IKEEDFITRLLVANTHDTILLFSNYGRIYWMKVYRLPVSNRGSRGKPIINLLPLE-DE
RITAILPVRKYEAGYYVFMATSMGIVKKTSLIQFSRPRSAGIIAINLSKGDELIGVNLTNGENEVMLFSSYGKVVRFFEKQVRNMGRTAVGVKGINLV--
EGVVSLIVPLN-SSILTVTQHGYGKRTAQVEYPVRSRATQGVISIKVSE-RNGKVVGAVQANDCDQIMMITDAGTLVRIPVSEVSIIGRNTQGVVLIRTV
ENRVVGLQRVA-
>tr|H6Q5V6|H6Q5V6_WIGGL DNA gyrase subunit A OS=Wigglesworthia glossinidia endosymbiont of Glossina morsitans morsitans (Yale colony) GN=gyrA PE=3 SV=1
IEDLINKKDVVVTLSHQGYVKYQPLKDYEAQHRGGKGSATS-IKEKDFIERFLVANTHDSILLFSSRGRVYWMKIFQLPETNRGSSGKPIINLLPLE-KE
YITAILPVHKHEKEKYVFMATASGIVKKTSLSEFSRPRNSGIIAVNLNAGDKLIGVDLTDGSQEVMLFSEYGKVVRFSESQVRNMGRTASGVKGISLL--
PGVVSLIIPKG-SPILTVTQYGYGKRTNQSEYPKKSRAIQGVISIKVSK-RNGKVVGAVQVNDYDQIMIITDSGTLVRTRVSEVNIVGRNTHGVRLIRIS
KENVVGLQRVV-
>tr|A0A077HHT9|A0A077HHT9_9CORY DNA gyrase subunit A OS=Corynebacterium ureicelerivorans GN=gyrA PE=3 SV=1
EEDLIARENVVVTITSTGYAKRTKVDAYKSQKRGGKGVRGA-EKQDDVVKNFFICSTHDWILFFTNFGRVYRLKAYELPEAGRTARGQHVANLLEFQPEE
KIAQIIQIQ---AP-YLVLATRDGRVKKSRLTDYES-RSAGLIAINLNE-DSLIGAC--GEDDDVLLVSEQGQAIRFSE--LRPMGRATAGVKGMRFR-D
-DLLAMTVAK-GEYLLVATSGGYGKRTAIEEYNAQGRGGMGVMTFKYS-PKRGKLIGALSVAD-DQIFAITSAGGVIRTEVNQIRP-SRATMGVRLVDLA
-GELLAIDRNV-
>tr|S5TFS4|S5TFS4_9CORY DNA gyrase subunit A OS=Corynebacterium maris DSM 45190 GN=gyrA PE=3 SV=1
AEDLIARENVVVTITSTGYAKRTKVDAYKSQKRGGKGVRGA-EKVDDVVKNFFICSTHDWILFFTNFGRVYRLKAYELPEASRTARGQHVANLLELQPEE
RIAQVIQIS---AP-YLVLATKDGRVKKSRLKDYES-RHAGLIAINLNE-DSLIGAA--NDNEDLLLVSERGQAIRFTE--LRPMGRATAGVKGMRFR-E
-DLLAMTVVH-GQYLLVATSGGYGKRTPIEEYTTQGRGGMGVMTFKYT-PKRGKLVSAVTVDD-DQLFCLTSVGGVVRTEVNQIRP-SRATMGVRLVDLA
-DELTVVDVNV-
>tr|U2GMH5|U2GMH5_9CORY DNA gyrase subunit A OS=Corynebacterium pseudodiphtheriticum 090104 GN=gyrA PE=3 SV=1
DEDLIVRENVVVTITATGYAKRTKVDTYKSQKRGGKGVRGA-EKQDDVVKNFFVCSTHDWILFFTNFGRVYRLKAYELPEAGRTARGQHVANLLEFQPEE
RIAQVIQLQ---AP-YLVLATKQGRVKKSHLTDYES-RSAGLIAINLNE-DALIGAC--GDEDDLLLTSEQGQSIRFTD--LRPMGRATAGVKGMRFK-D
-DLLAMSVVH-GEYLLVATSGGYGKRTAIEEYSTQGRGGMGVMTFKYT-PKRGKLIGAIAVND-DEIFAITSAGGVVRTEAGQIRP-SRATMGVRLVNLA
-DELLAIDKNV-
>tr|A0A097ICN0|A0A097ICN0_9CORY DNA gyrase subunit A OS=Corynebacterium doosanense CAU 212 = DSM 45436 GN=gyrA PE=3 SV=1
AEDLIARENVVVTITQTGYAKRTKVDAYKSQKRGGKGVRGA-EKQDDVVKNFFICSTHDWILFFTNFGRVYRLKTYQLPEASRTARGQHVANLLELQPEE
RITQVIQIR---AP-YLVLATKDGRVKKSRLTDYES-RQAGLIAINLNE-DALIGAQ--DDGDDVLLVSEKGQAIRFTE--LRPMGRATAGVKGMRFR-D
-DLLAMTVVR-GEFLLVATSGGYGKRTPIGEYATQGRGGLGVMTFKYS-PKRGKLIGALAVDD-DQIFAITAAGGVIRTEVNQIRP-SRATMGVRLVDLA
-GELLAIDVNV-
>tr|R5GKC4|R5GKC4_9FIRM DNA gyrase subunit A OS=Eubacterium sp. CAG:786 GN=gyrA PE=3 SV=1
IEDLIPEEDCVVTYTNIGYIKRQPVELYNIQKRGGKGVSGMKQ-DEDFVENMFISSSHENILFITNQGNMYRMKCYEIPES-KQARGMNIVNLLQLNEGE
RVAAMMTTHA--DNKYFICVTKNGTVKRTNLSEYKNVRKKGLRAITLAEGDEIASAFLTEGDCRILTATRNGSAICFD---CRPLSRQARGVKAIKLR--
-YVVGATKV--NATILTVTDMGMGRRCAVSSYRLQKRGGFGMKNYKVSD-EKGYVCGIRTLG-DDDVILISTDGVIIRFRANDMRV-GRSATGVRVMRLS
-ERVASFTRTA-
>tr|D4MNV6|D4MNV6_9FIRM DNA gyrase subunit A OS=[Eubacterium] siraeum V10Sc8a GN=gyrA PE=3 SV=1
IEDLIPEEECVLTYTNIGYIKRQPVDVYNLQKRGGKGVSGMKQ-EEDFVEDMFISSTHDNILFITNYGNMYKLKCYEVPES-KQSRGTNIVNLLQLDEGE
RIAAMMKTSA--ENKYFICVTKYGKIKRTPLYDFRNVRKNGLRAITLAEGDEIAAAHLTEGDSSIIVATHLGMAIHFS---IRSMGRLAAGVRAIKLR--
-YIVGAAKV--DMRILTVTDKGYGRLSALSDYRMQNRGGNGLKNYKIRD-DRGYVCGIRSIQ-DDDVILISTDGVIIRIRANDLRV-RRTGLGVRVMKLS
-ERVVTFTRTE-
>tr|C7RAM0|C7RAM0_KANKD DNA gyrase subunit A OS=Kangiella koreensis (strain DSM 16069 / KCTC 12182 / SW-125) GN=gyrA PE=3 SV=1
IADLITEEDVVVTLSHEGYVKYQALSEYKAQRRGGRGSATK-MKDEDFIEKLLVASTHDTILCFSSTGKVYWLKVFELPNAGRGSRGKPIVNVLPLE-GE
RINAILPIREFSEDKFVFMATANGTVKKTSLEQFSRPRSNGIIALTIADDDELIGVVETDGSNHIMMFSDAGKVIRFDEANVRGMGRTARGVRGMKLPEA
K-VIQMIVAE-DGSVLTATENGYGKRTAMEDHPLRGRGGQGVISIQMSE-RNGAVVSAVPVIDGDEVMLISKGGTLIRTGVDDIRIMGRNTQGVRLIKLD
DGTLVGLQRIV-
>tr|A0A0F6RCW5|A0A0F6RCW5_9GAMM DNA gyrase subunit A OS=Kangiella geojedonensis GN=gyrA PE=3 SV=1
IADLITEEDVVVTLSHEGYVKYQSLSDYKAQRRGGRGSATK-MKDEDFIDRLLVASTHDMILCFSSRGKVYWLKVFELPNAGRGSRGKPIVNVLPLE-DE
KISAILPIREFSEDRFVFMATANGTVKKTSLEQFSRPRANGIIALTIADDDELIGVAETAGEDEIMLFSDAGKVIRFGEDAVRAMGRTARGVRGMKLPDA
K-VIQMLVAE-DCSILTATENGYGKRTSVEDHPLRGRGGQGVISIQMSE-RNGQVVSAVPVIEGDEVMLISKGGTLIRTGVDDIRIMGRNTQGVRLIRLD
DNTLVGLQRIV-
>tr|D8SVR4|D8SVR4_SELML Putative uncharacterized protein OS=Selaginella moellendorffii GN=SELMODRAFT_126010 PE=3 SV=1
NIDVIPNNESFLTLSEKGYIKRMQPDTFLAQRRGT-G--S-AK-ND-GMVDSFMCRNHDHVLVFSERGVVYSFRAYQVPES-RTSAGVPIIQVL-SPG-E
R--SIFPLS--REDHFLVMLTSKGYIKRTELPAFSS-R-QGIVAIQLM--DELKW---T---DRIFIGSRNGMAM------FRSMRRGARGLRAMRIKE-
-GIAAIDIVPGAPWLLFVSENGMAKRVPI-SFP-HGLNKVGVIGC---VPG--DL-SMFVVGDNEEIVVGTQGGIFNRFKV-EISI-SR---GIKLMKLD
D-KVKSVSVVA-
>tr|A9SV22|A9SV22_PHYPA Predicted protein (Fragment) OS=Physcomitrella patens subsp. patens GN=PHYPADRAFT_135715 PE=3 SV=1
DIDVIANEETIVTLSEKGYIKRMAAGTFTAQNRGT-G--SGK--ND-AMSDFFVCRTHDYVLFFSERGIVYSIRAYQIPES-RTSAGNPLVQVVPV-G-E
R--SVQSVS--AEDQYLVMLTTGGYIKRTALSSFAS-R-TGIVAIQLT--DELKW---AD---TVALASQRGMVV------DKVLGRATRGVRAMRLR--
-DLTAMDIVPAAPWLLMVTEDGFGKRVPI-AFP-GVAGRVGVIGC---KTD----------G-EEQVVVGSNKGILNRLRV-DVSI-SR-----------
------------
>tr|A0A0G3EIK4|A0A0G3EIK4_9BACT DNA gyrase subunit A OS=Verrucomicrobia bacterium L21-Fru-AB GN=gyrA_1 PE=3 SV=1
MEDLIADAPCVVTLSRADYIKRVPVDTYRQQRRGGKGVRGMAT-DEDAVKHVMTAMLHDTMLCFTETGRLYRLKTWQIPEAARQSRGRSVANLL-QEEEE
SLASIHCVR---DDCCLLMATRKGIVKKTPLSAYRNIRTVGIRAVNVEDGDRLVGVR-VREGDDVLLTTRRGMTIRFSE--ARPMGRVARGVRGISLS--
-DVVSLEIVDP-TDLLTVTEQGYGKRTSFDEYRRQSRGGKGLIGI--TR--NGNVVGAHAVREEDGVMLITQSGQLVCIAVNEVSRIGRNTQGVRLVRLN
-DRLVSAAVLL-
>tr|A0A011P2Q6|A0A011P2Q6_9PROT DNA gyrase subunit A OS=Candidatus Accumulibacter sp. BA-93 GN=gyrA PE=3 SV=1
IADFITPVDMVVTLSHTGYIKSQPLADYRAQRRGGRGQAAA-MKTDDFVDRLFVANTHDSILCFTNRGRVYWLKVYEVPQGTRTSRGKPVVNVFPFE-GE
KISAILPIKEF--DRYIFMATSQGTVKKTPLSDFSNPRKNGIIAVALDDEDFLIGAEVTNGSQDVILVSDAGKAVWFDE-DVRPMGRTARGVRGMRLA--
DRVLSLLIADSQQTVLVATENGFGKRTALADFRHSGRGTQGVIAISASE-RNGKVVAARLVSDDDEIMLITTGGVLIRTRVREIRELGRATQGVTLIALD
PGKLAGLEKVV-
>tr|A0A084Y0J4|A0A084Y0J4_9PROT DNA gyrase subunit A OS=Candidatus Accumulibacter sp. SK-01 GN=gyrA PE=3 SV=1
IEDFITPADMVVTLSHTGYIKAQPLADYRAQRRGGRGQAAA-MKADDFVDHLFVANTHDFILCFTNRGRVYWLKVYEVPQGTRSSRGKPIVNLFPFE-GE
KISAILPVKEF--DRYIFMCTANGTVKKTPLSDFSNPRKAGIIAVALDEDDVLIGAEITNGLQDVVLVSDVGKAVWFDE-EVRPMGRTARGVRGMRLA--
DQVLSLLVADNQQTVLVATENGFGKRTVLADFRHSGRGTQGVKAIAASE-RNGKVVAARLVRDEDEIMLITTGGVLIRTRVREIRELGRATQGVTLIALD
AGKLAGLEKVV-
>tr|F2I5D3|F2I5D3_AERUA DNA gyrase subunit A OS=Aerococcus urinae (strain ACS-120-V-Col10a) GN=gyrA PE=3 SV=1
DEDLIEESNVLITLSRKGYIKRVEDSEYRTQNRGGRGVKGMAL-DGDHIDAMLSTSTHDVILCFTDRGRVFQIKGYEIPEYGRAAKGLPIVNLLNL-QDE
QVRGVINVT--DSEDYFFFVTKQGTVKRTPVEEYFN-RNNGLIAINLRDDDELVAVL-TSG-DNIILGSHQGYAVSFAE--VRSMGRTATGVRGIRLD--
-DVVGASILGPDQDVLIVTEKGYGKRTPADEYSIKHRGGKGVKTVNIT-E-NGPLVGLATVDD-EDIMLMTDEGVVIRFHSVDISQTGRATQGVRLMRLD
A-HVSTMAVVD-
>tr|D4YHA6|D4YHA6_9LACT DNA gyrase subunit A OS=Aerococcus viridans ATCC 11563 GN=gyrA PE=3 SV=1
DEDLIEESNVIVTLTQNGYIKRIDDVEFRAQNRGGTGVKGMSM-DDDFVETMLSTSTHDSVLFFTNTGRVFHSKGYEIPEFGRAAKGIPVVNLLNL-QDE
TVQAMINVT---VKEHLLFVTKNGTVKRTNASDYFN-RNNGLIALKLAEGDELVKVV-TSG-DNIIIASRDGYAVSFQE--VRSMGRTATGVRGIRLN--
-GVVGMSVLGPDDNVLVVTEKGYGKQTPASEYGIKNRGGKGVKTINVT-E-NGILVGLTTVSE-EDIMLMTNQGIAIRFHAKNISQTGRATQGVRLIRLA
D-YVSAIAKVE-
>tr|K4IIR4|K4IIR4_PSYTT DNA gyrase subunit A OS=Psychroflexus torquis (strain ATCC 700755 / ACAM 623) GN=gyrA PE=3 SV=1
MEDMIPNESVVLTISHAGYIKRTPLKEYKIQNRGGVGQKASTT-DEDFLEYIFSGTNHQYILFFTQKGKCFWMRVFEIPEGSKTSKGRAIQNLMNLDPDD
RINAFILVES--NNHYVLMVTKKGQVKKTILEQYSR-RINGINAISVRDGDELLSAVLTDGENQVMLGLRSGKALRFE---IRPMGRGAAGVKGITLAE-
-DVIGMICVKNEETVLVVSEKGYGKRTFIDVYRITNRGGKGVKTISISE-KTGQLVAMKTVH-EDDLMIIKKSGVAIRMSVSDIRTMGRSTQGVRLISLK
-DEIAAVAKII-
>tr|H8XU39|H8XU39_FLAIG DNA gyrase subunit A OS=Flavobacterium indicum (strain DSM 17447 / CIP 109464 / GPTSA100-9) GN=gyrA PE=3 SV=1
IEDLIADENVVITISHAGYIKRTSLSEYKTQNRGGVGQKGSAT-DQDFLEHLFVATNHQYLLFFTQKGKCFWMRVFEIPEGSKASKGRAIQNLINIEQDD
KVKAFICTQK--NSHYVIMATKQGQVKKTPLEQYSR-RQNGINAITIKEDDELIGAKLTTGNSQVLIAVKSGKLVRFE---TRPMGRTASGVRGITLAD-
-DVIGLVSIDKDSQILVVTENGYGKRTKVVVYRITNRGGKGVKTLNITD-KTGQLISINDVT-EDDLMIINKSGLTIRMKVSDLRIMGRATQGVRLINIK
-NSIAAVTKVM-
>tr|K9UZ17|K9UZ17_9CYAN DNA gyrase subunit A OS=Calothrix sp. PCC 6303 GN=gyrA PE=3 SV=1
DIDLIANEKAIILVTQQGYIKRMPVNTFESQNRATRGKAAAKV-DDDNIEHFLTCCDHDSVLFFSDRGVVYSLRAYQIPVSSRTSRGTPIVQMLPIPKEE
KITSVVHVD---SEEYLVMLTRGGNIKKTALEAFSHIRSNGLIAISLEEGDQLRWVRRAKPEDSVLIGSRQGMAIHFRC--LRPLGRATRGVKSMKLK--
-DLVGMDILPAGLWVLVITMGGYGKRVPVAQFRLQNRAGQGLMATKFKKS-KDKLAALHIVNDD-EIMMVTSRGIIIRQAVNAISVQSRSATGVRVQRLD
-DALTGVAVVP-
>tr|R7GUN8|R7GUN8_9BACT DNA gyrase subunit A OS=Prevotella stercorea CAG:629 GN=gyrA PE=3 SV=1
AEDFYPNDPVVITVSHMGYIKRTPLSEFREQSRGGVGSKGART-EQDFTEYIYPATMHQTMLFFTRKGRCYWLKCYEIPEGDKNFKGRAIQNMLNIDPDD
SVNALLRLRN--KSHYVVFATKNGTVKKTSLEAYSR-RTNGVNAINIVEGDEVVDVRLTNGKNEIILANRNGRAVRFD---IRTMGRVSTGVRGMKLD--
-DVVGMIVVNNTETVMVVSENGYGKRSQVE-YRKTNRGGKGVKTFSITE-KTGRLVAIKNVT-DNDLMIINKSGIAIRLAVSECRVMGRATQGVRLINLS
KNVIASVCKVM-
>tr|D5EZ76|D5EZ76_PRER2 DNA gyrase subunit A OS=Prevotella ruminicola (strain ATCC 19189 / JCM 8958 / 23) GN=gyrA PE=3 SV=1
AEDFYPDDPVVITISHMGYIKRTPLSEFHEQGRGGMGSKAARH-DNDFTEYIYPATMHNTLLFFTQKGRCYWQKCYEIPEGDKNSKGRAIQNMLNIEPDD
AINAVLRIKN--NSHYVVFATKQGIIKKTCLEAYSR-RANGVIAININEGDQVVGVRLTNGHNELLLANRNGRAVRFD---VRVMGRVSTGVIGMRLD--
-DVVGMVCVNDTETIMVVSENGYGKRSEVE-YRKTSRGAKGVKTLSITE-KTGRLVAIKVVT-ENDLMIINKSGVLIRLKVADVRVMGRATQGVRLINLT
KNSIASVCKVM-
>tr|D3IAN4|D3IAN4_9BACT DNA gyrase subunit A OS=Prevotella sp. oral taxon 299 str. F0039 GN=gyrA PE=3 SV=2
AEDFYPNDPVVITVSHLGYIKRTPLSEFREQARGGVGSKGVRH-EQDFTEFIYPATMHQTMLFFTKKGRCYWLKCYNIPEGTKDSKGRAIQNLLNIDPDD
GLNAILRLRD--NSHNVVFATKNGTIKKTSLEAYSR-RANGVIAINIAEGDEVVDVRLTNGKNEIIMANKNGRAVRFN---VRAMGRTATGVRGMKLD--
-DVVGMIVVNDAENVMVVSETGYGKRSSVE-YRVTNRGGKGVKTLNITE-KTGRVVAIKNVN-DNDLMIINKSGITIRLAVSEVRVMGRATQGVRLINLS
KNVIASVCKVM-
>tr|E0NRN6|E0NRN6_9BACT DNA gyrase subunit A OS=Prevotella marshii DSM 16973 = JCM 13450 GN=gyrA PE=3 SV=1
PEDFYPNDPVVITVSHLGYIKRTALSEFKEQARGGVGSRGSRT-EEDFTEFIYPATMHNTMLFFTRKGRCYWLKCYEIPEGTKDSKGRAIQNMLNIDSDD
SVNAFLRLKD--NSHYVVFATKNGVVKKTLLKAYSR-RANGVNAINIVDGDEVVNVRLTNGSNELILANRNGRAVRFD---VRTMGRVSTGVRGMRLD--
-DVVGMVVVNEKESVMVVSENGYGKRSSVE-YRKTNRGGKGVKTLSITD-KTGRLVSIKNVT-ENDLMIINKSGITIRLAVSNVRVMGRATQGVRLINLT
KNVIASVCKVM-
>tr|A0A099BVU6|A0A099BVU6_9BACT DNA gyrase subunit A OS=Prevotella sp. S7 MS 2 GN=gyrA PE=3 SV=1
PEDFYPNDPVVITVSHMGYIKRTPLSEFREQARGGVGSKGARH-EQDFTEFIYPATMHQTMLFFTRKGRCYWLKCFEIPEGDRNSKGRAIQNMLNIEPDD
AINAILRLRD--NSHYVVFATKNGTVKKTSLEAYSR-RANGVIAINIAEGDEVIDVRLTNGRNELILANRNGRAVRFN---IRTMGRTATGVRGMRLD-K
-DVIGMIVVDDKETVMVVSEQGYGKRSDVE-YRVTNRGGKGVKTLAITE-KTGKLVSIKNVT-DNDLMIINKSGIVIRLAVSDVRTMGRATQGVRLINLA
KNVIASVCKVM-
>tr|U2MU69|U2MU69_9BACT DNA gyrase subunit A OS=Prevotella pleuritidis F0068 GN=gyrA PE=3 SV=1
AEDFYPNDPVVITVSHLGYIKRTQLSEFREQARGGVGSKGANT-DKDFTEYIYPATMHQTMLFFTKKGRCYWLKCYEIPEGDKISKGRAIQNLLNIDPDD
AVNAFLRLKN--NSHYVVFATKNGVVKKTCLEAYSR-RTNGVIAINITDNDEVIDVRLTNGKNEIIMANRNGRAVRFD---IRTMGRTATGVRGMRLD--
-DVVGMIVVNDNETVMVVSEEGYGKRSDVE-YRKTNRGGKGVKTLSITE-KTGRLVSIKNVT-DNDLMIINKSGIVIRLAVADVRVMGRATQGVRLINLA
KNVIASVCKVM-
>tr|C9PYD7|C9PYD7_9BACT DNA gyrase subunit A OS=Prevotella sp. oral taxon 472 str. F0295 GN=gyrA PE=3 SV=1
AEDFYPNDPVVITVSHLGYIKRTPLSEFHEQARGGVGSKGANT-DKDFTEYIYPATMHQTMLFFTKKGRCYWLKCYEIPEGDKTSKGRAIQNLLNIDADD
SVNAFLRVKN--KNHYIVFATKNGTVKKTSLEAYSR-RTNGVNAITIAEGDEVVDVRLTNGKNLLIMANRNGRAVYFD---VRTMGRTATGVRGMRLD--
-DVVGMIVVNDTETVMVVSETGYGKRSFVA-YRKTNRGGKGVKTLNITD-KTGKLVAIKNVT-DNDLMIINKSGIAIRLAVANFRVMGRATQGVRLINLS
KNVIASVCKVK-
>tr|A0A098YRP6|A0A098YRP6_9BACT DNA gyrase subunit A OS=Prevotella timonensis S9-PR14 GN=gyrA PE=3 SV=1
AEDFYPNDPVVITVSHLGYIKRTPLSDFREQARGGVGSKGATH-NADFTEFIYPATMHQTMLFFTKKGRCYWLKCYNIPEGTKDSKGRAIQNLLNIESDD
AINAILRLRD--NSHYVVFATKNGTVKKTCLEAYSR-RTNGVIAINIAEGDEVVDVRLTNGENELIMANRNGRAVRFD---IRVMGRTATGVRGMRLD--
-DVIGMIVVDDNETVMVVSENGYGKRTLVE-YRKTNRGGKGVKTMSITD-KTGRLVAIKNVT-DNDLMIINKSGITIRLSVAECRVMGRATQGVRLINLS
KNIIASVCRTM-
>tr|D8DZ12|D8DZ12_PREBR DNA gyrase subunit A OS=Prevotella bryantii B14 GN=gyrA PE=3 SV=1
PEDFYPNDPVVITVSHLGYIKRTPLSDFREQARGGVGSKGART-EQDFTENIYPATMHQTMLIFTKKGRCYWLKCYEIPEGDRNSKGRAIQNMLNIEKDD
AVNGFLRLRT--NSHYVIFATKNGTVKKTCLEAYSR-RANGVIAINLAEGDELVDVRLTNGENELIIANRNGRACRFH---IRTMGRTATGVRGMKLD--
-DVVGMVPVNNVETVMVVSEQGYGKRSQVE-YRITNRGGKGVKTLAITE-KTGRLVAIKNVT-ENDLMIINKSGIAIRLSVADVRVMGRATQGVRLINLS
KNIIASVCKVM-
>tr|U2P9Y9|U2P9Y9_9BACT DNA gyrase subunit A OS=Prevotella baroniae F0067 GN=gyrA PE=3 SV=1
PEDFYPNDPVVITVSHMGYIKRTPLSDFREQARGGVGSKGARH-EQDFTEFIYPATMHQTMLFFTKKGRCYWLKCYEIPEGGKDSKGRAIQNMLNIEPDD
AINAILRLKN--NSHYVVFATKNGTVKKTSLEAYSR-RTNGVIAINITEGDEVVDVRLTNGDNELIIANKNGRAVRFN---VRTMGRTATGVRGMRLD--
-DVVGMVVVNNEETIMVVSENGYGKRSQVE-YRVTNRGGKGVKTLNVTE-KTGLLVAIKNVT-ENDLMIINKSGIVIRLAVADCRVMGRATQGVKLINLE
KNVIASVCKVM-
>tr|R6B073|R6B073_9BACT DNA gyrase subunit A OS=Prevotella sp. CAG:604 GN=gyrA PE=3 SV=1
PEDFYPNDPVVITVSHLGYIKRTPLSEFREQARGGVGAKGART-DKDFTEFIYPATMHQTMLFFTKKGRCYWLKCYEIPEGDRNSKGRAIQNLLNIESDD
QVNAFLRLRN--NNHYVVFATKNGTVKKTCLEAYSR-RANGVIAINIVEGDEVVDVRLTNGHNELILANRNGRAVRFD---IRTMGRTSTGVRGMRLD--
-DLIGMIVVNDHETVMVVSEQGYGKRSDVI-YRVTNRGGKGVKTLNITE-KTGRLVAIKNVT-DNDLMIINQSGIVIRLAVADCRIMGRATQGVRLINLT
KNVIASVCKVM-
>tr|A0A0M2GWY7|A0A0M2GWY7_9MICO DNA gyrase subunit A OS=Microbacterium ketosireducens GN=gyrA_2 PE=3 SV=1
MEDLIAEEEVVVTVTRDGYIKRTRSDNYRSQHRGGKGVKGA-QRADDVVEHFFVTTTHHWLLFFTTKGRVYRSKAYELPEAGRDAKGQHAANFLALQPDE
EIAQILDIR---AT-YLVLATRGGLVKKTRLTDYDT-RQGGVIAIRLRESDEVVSAM--DEGDDILLISRHGMSLRFTD--LRPMGRSTEGVKGMSFR-R
-DLLSASVVRDEGYVFVVTEGGYAKRTSVDQYRVQSRGGLGIKVAKLH-E-RGDLAGGLIVSI-DEVLVVLASGKVVRSAVAEVPA-GRDTMGVVFARAA
-DRILAIARNG-
>tr|A0A0Q8B0R9|A0A0Q8B0R9_9MICO DNA gyrase subunit A OS=Microbacterium sp. Root166 GN=ASD56_04765 PE=4 SV=1
IEDLIPEEEMVLTVTRDGYIKRTRSDNYRQQHRGGKGVKGA-QRADDVVEHFFVTTTHHWLLFFTTKGRVYRSKAYEVPEAGRDAKGQHVANLLALQPDE
EIAQILDIR---AE-HLVLATRSGLVKKTRLTEYDT-RQGGVIAIKLREGDEVVSAL--ESGDDILLISRHGMSLRFTE--LRPMGRSTEGVKGMSFR-D
-DVLSASVVKDDGSVFVVTEGGYAKRTAVDQYRTQSRGGLGIKVARLT-D-RGVLAGGLIVAD-DEVLVVLASGKVVRSAVAEVPA-GRDTMGVVFARAA
-ERIIAIARNG-
>tr|A0A0F0KW44|A0A0F0KW44_9MICO DNA gyrase subunit A OS=Microbacterium azadirachtae GN=gyrA_1 PE=3 SV=1
MEDLIAEEEMVVTVTREGYIKRTRSDNYRSQHRGGKGVKGA-QRADDLVEHFFVTTTHHWLLFFTDKGRVYRTKAYEIPEAGRDAKGQHVANLLALQPDE
KIAQILDIR---AQ-YLVLATRGGLVKKSRLGDYDT-RQGGVIAIRLREEDELVSAF--DATDDVLLISRHGMSVRFHE--LRPMGRATEGVKGMRFN-D
-DLLSASLVTAEGYVFVVTDGGYAKRTSVDEYRVQGRGGQGIKVAKLN-D-RGILAGGLIVQD-DEVLVVLASGKVVRSAVAEVPA-GRNTMGVVFARTD
-DRILAIARNT-
>tr|A0A0Q6E9F5|A0A0Q6E9F5_9MICO DNA gyrase subunit A OS=Microbacterium sp. Leaf436 GN=ASG45_01485 PE=4 SV=1
IEDLIAEEEMVVTVTRDGYIKRTRSDNYRSQHRGGKGVKGA-QRADDVVEHFFVTTTHHWLLFFTNKGRVYRSKAYEVPEAGRDAKGQHVANLLALQPDE
EIAQILDIR---ST-YLVLATRGGLVKKTRLAEYDT-RQGGVIAIKLRGADELVSAM--DEGDDILLISRLGMSLRFSS--LRPMGRSTSGVKGMEFR-G
-DLLSASVAQDDEFVFVVTEGGYAKRTAVTEYRMQNRGGLGIKVARLT-D-RGTLAGGMMVSG-DEVLVVLASGKVVRSAVAEVPA-GRDTMGVVFARAG
-DRIIAIARNA-
>tr|A0A0B3A943|A0A0B3A943_9ARCH DNA gyrase subunit A OS=archaeon GW2011_AR4 GN=gyrA PE=3 SV=1
REALIKPEQMVVTITHAGYIKRTAMALYREQKRGGRGIKAAGT-EEDFVKDVFVANTHDTMLFFTNKGMVHWLKVYDIPETARHAKGKPVVNLISLSEGE
NISAIVPVD---DYHFILMGTEQGIVKKTNLIEYSRPRKGGIIGITLREGDSLIEVK-TDGKQQVILATTSGMANRFNE--VRPMGRGASGVIGIRLK--
-DVVGMVLGEDDHYLLTITEQGYGKRTTMSEYRLTARGSSGVRNI--SR--NGVVVGVLSVVDNDQVLFISKNGVVIRTSAAAIRPIGRNTQGVRLMKLE
-ESVASAARIP-
>tr|A0A0C2BY11|A0A0C2BY11_9BURK DNA gyrase subunit A OS=Herbaspirillum sp. TSA66 GN=gyrA PE=3 SV=1
TEDLITPQDMVVTLSHAGYMKSQPVSEYRAQKRGGRGQAMA-TKEDDWIDQLFIANTHDYILCFSNRGRMYWLKVWEVPQGSRNSRGKPIVNMFPLQ-GE
KITVVLPLSSF--DHYVFMATSLGTVKKTPLTEFSNPRKAGIIAVDLDEGDYLIGAALTDGKHDVMLFSDAGKAVRFDENDVRPMGRTARGVRGMSLE--
EGVIALLVAEN-QTVLTATENGYGKRTPITEYTRHGRGTKGMIAIQTSE-RNGKVVAATLVEPTDEIMLITTGGVLIRTRVSEIREMGRATQGVTLIAVE
DGKLSGLQRIV-
>tr|C3X754|C3X754_OXAFO DNA gyrase subunit A OS=Oxalobacter formigenes HOxBLS GN=gyrA PE=3 SV=1
TEDLITPQDMVVTLSHSGYIKSQPLSEYRAQKRGGRGQATS-TKEDDWVDQLFIANTHDYILCFSDRGRMYWLKVWEVPQGSRNSRGKPIVNMFPLQ-EE
KITVILPLSNF--NHYIFMATSQGTVKKTPLTDFSNPRKAGIIAVGLDEGDYLIGAALTDGNHDVMLFSDAGKAVRFDENDVRPMGRTARGVKGMNLE--
DEVIALLVAGD-QSVLTATENGFGKRTPIAEYTRHGRGTKGMIAIQTSE-RNGKVVAATLVSENDEIMLITTGGVLIRTRVSEIREMGRATQGVTLISIE
EGTLSGLQRIL-
>tr|A0A0A2BN07|A0A0A2BN07_9PROC DNA gyrase subunit A OS=Prochlorococcus sp. MIT 0602 GN=gyrA PE=3 SV=1
DIDLIANERSVVLLTETGYLKRMPVNEFESTSRGTRGKSGTRS-GEEEVKRFISCNDHDNLLLFSAKGVAYSVPAYRVPQCSRAAKGTPVVQLLPIPREE
AITSLISVS---EDNHLLMLTTGGFIKRTPVSAFSKIRANGLISINLEEGDSLRWVKLASSGDSVLIGSRTGMTIHFRL--LRPLGRTARGVRSMNLR--
-DLVSMDVLSKGPWVLVASANGLGKRVPVTQFRLQKRAGMGLRAIKF--E-RDKLVGLKVLD-GEELLLVSEKGVIVRTSADKVSQQSRAATGVRLQRLD
-GHLAEVVLVP-
>tr|A0A0A2BE88|A0A0A2BE88_9PROC DNA gyrase subunit A OS=Prochlorococcus sp. MIT 0601 GN=gyrA PE=3 SV=1
DIDLIANERSVVLLTETGYLKRMPVNEFEATSRGTRGKSGTRS-GEEEVKLFISCNDHDNLLLFSDRGVAYTLPAYRVPQSSRSAKGTPVVQLLPIPREE
AITSLLSVS---DDNHLLMLTKGGYIKRTSVSAFSKIRANGLIAISLEEGDALTWVRLAASGDSVLIGSKAAMTIHFRL--LRPLGRTARGVRSMNLR--
-DLVSMDVLPRGPWVLVASADGLGKRVPVTQFRLQKRAGMGLRAMKF--Q-SDSLVGLKVLG-GEELLLVTEKGVIVRTSADKISQQSRAATGVRLQRLD
-GHLAEVVLVP-
>tr|D9W2Y3|D9W2Y3_9ACTN DNA gyrase subunit A OS=Streptomyces sp. C GN=gyrA PE=3 SV=1
IEDLIAEEDIVVTITHGGYVKRTKTEDYRSQKRGGKGVRGT-KKQDDLVDHFFVSTTHHWLLFFTNKGRVYRSKAYELPDAGRDARGQHVANLLAFQPDE
KIAQVLAIR---AP-YLILATKGGLVKKTALKDYDS-RSGGVIAINLREADELIGAE--SAEDDLLLISKKAQSIRFTE--LRPMGRATSGVKGMSFR-G
-DLLSMSVVRPGTFVFTATDGGYAKRTAVDEYRVQGRGGLGIKAAKIV-EDRGSLVGALVVDS-DEILAITLGGGVIRTRVSEVRE-GRDTMGVQLINLG
-RAVVGIARNA-
>tr|A0A0J0UYK5|A0A0J0UYK5_9ACTN DNA gyrase subunit A OS=Actinobacteria bacterium IMCC26207 GN=gyrA PE=3 SV=1
IEDLIDDEEVVVVMTARGYVKTVAADTFRTQARGG-G--AAR--ED-YITDLIFTSAHAFLLFFSNKGKVYRLKAHRIPMD-RTAQGLAIVNLL-QDG-E
K--TIIDTR--ESHRYLMFVTRNGIVKKTMFNAYDS-R-AGLIAINLR--DELVR---TD---EIMVISESGQGI------IRPTGRTASGVRGMRLKA-
-NVVGADSIAATLRLLTITDGGYGKRTEL-EFS-QRRGGQGVRAH---HAARGRV-TGFLVG--DHLLMINDAGVVIRTKV-TISI-GR---GVRVMNLD
--KVAAVARVL-
>tr|A0A0G3UY27|A0A0G3UY27_9ACTN DNA gyrase subunit A OS=Actinobacteria bacterium IMCC26256 GN=gyrA PE=3 SV=1
DLDLIEDEEVIVVLTNKGYIKTVAADAFRKQARGG-G--RQA--GD-FVSHLLTSTMHSYLLFFSNRGKVYRLRAHEIPME-RTARGTAVVNLI-AGD-E
K--AVIDTR---DGTFLFFATKQGQVKKTKMGEYDS-R-TGLIAINLK--DELVG---TE---DIFMVSRSGMTI------VRPLSRGAAGVRGMKLKN-
-AVVSCDVARD-AVMLFVSASGHGKRTKL-RFN-QGRGGQGVRGM---TAGRVGV-AAFTVL-DDEILVFSSTGNVVRLAA-EISS-GR---GVKVSSVG
G-TVVAVALVL-
>tr|A0A0D8HH40|A0A0D8HH40_9ACTN DNA gyrase subunit A OS=Acidithrix ferrooxidans GN=gyrA PE=3 SV=1
DEDLIEDEPRVVILTKSGYIKAMSSDSFRTQARGG-G--QAK--ED-VVSEVLHTNSHSYLLFFTNKGKVYRIKTHELGVE-RTARGMALVNLL-ADD-E
S--TVLDTQ---PDSFLVFFTRMGLVKKTRLAEYDK-R-EGLIALALR--DELVK---VS---DILVLTKHGMGI------VRPVGRSASGVRAIRLRI-
-DVAAIE-TGT-SEVLMVTGAGFAKRTKV-RFS-QTRGGQGVRAI---THARGEV-AAFATS-NDEVIVVASGGTTIRTTV-SIAD-GR---GVKIIELD
T-FVSSVTPVV-
>tr|R4YWH2|R4YWH2_9ACTN DNA gyrase subunit A OS=Candidatus Microthrix parvicella RN1 GN=gyrA PE=3 SV=1
VEDLIDDEDVVVVMTSRGYIKTTSLDAFRTQGRGGRGVAGAKL-DEDMITTLIKTSAHAYLLFFTNRGKVYRLKVHRIPMMDRGAQGTAIVNLLRLASDE
RVEAVID---Y-SHRYLMFTTSHGVVKKTRFTAYDSSRQDGLIAVSLRDGDELVEVL-VNDDDEVMLVSSSGMGIRFAE--VRPMGRNAAGVRGMRLK--
-DVIGSAVITPDTRLLTVTDGGYGKRTDPDEFTRQGRGGQGVRAH--RD--RGRVVAANLVAEDSEIFLITDAGVIIRTPVGSISEYGRDAMGVTVMRLD
-DKVVAVAPVV-
>tr|R7F500|R7F500_9BACT DNA gyrase subunit A OS=Prevotella sp. CAG:485 GN=gyrA PE=3 SV=1
AEDFYPDDEMIITISHLGYIKRTPLAEFRAQHRGGVGSRGSSS-EADFIEHIYPASNHNHILFFTRKGRCYWLKVYEIPEGAKNSKGRAIQNLLNLDGDD
QVNAFIRVKQ--TSHNLIFCTRQGIIKKTSLEAYSR-RTNGVNAIIIREGDQVIQVRLTDGNADIMLANRKGRAVRFH---VREMGRMSTGVRGMTLDE-
-DVIGMITLRGEETVMVVSENGFGKRSIPAEYRITNRGGKGVVTMNVTE-KTGMVVAIKNVT-ANDLMIINQSGVTLRLPVDTIRVTGRATQGVKLIDLR
RGVIASVCKVE-
>tr|R7J0R4|R7J0R4_9BACT DNA gyrase subunit A OS=Prevotella sp. CAG:873 GN=gyrA PE=3 SV=1
AEDFYADDDMIITISHLGYIKRTPLSEFRAQNRGGVGAKGSNT-EEDFIEYIYTASMHATMLFFTSRGLVYKMRVFELPEGAKNSKGRALQNLLNIEPND
KVNVFIACK-L-NSHNLVFATERGVVKKTSLAEYARVLAKGKKAIVLRDGDHLVSVQLTDGNSQILLANSGGRAIRFDE-KIRQMGRVSTGVRGMTLDD-
-RVVGMISISPSNTILALSEKGMGKRTPLEPYRVTGRGGKGVLTM--SE-KTGELVAFLSVNDDEDLVIINRSGIALRIRIADVPVLSRSTMGVRIINLN
-RDEIASACAV-
>tr|R5APD5|R5APD5_9BACT DNA gyrase subunit A OS=Prevotella sp. CAG:1031 GN=gyrA PE=3 SV=1
AEDFYADDDMIITISHLGYIKRTPLNMFRAQGRGGIGVRGSNT-DTDFIEYIYTASMHSTLLFFTNSGRCYWLKVYELPEGAKNSKGRAIQNLLNINAND
KISAVIPVKE--STHNLVFATKNGVIKKTRLEAYSR-RRDGVNGIIIRPDDQLINVALTDGNSQILLANRNGRAIRFD---VREMGRVSTGVRGMTIDG-
-DVVGMICMEPQNTVLVISENGYGKRSLLDAYRITNRGAKGVKTINVTE-KVGKLVGILSVN-DNDIMIINKSGITLRINASAIRVMGRAAQGVRLINLG
RNSIASVCCVA-
>tr|G8TFI5|G8TFI5_NIAKG DNA gyrase subunit A OS=Niastella koreensis (strain DSM 17620 / KACC 11465 / GR20-10) GN=gyrA PE=3 SV=1
IKDLIKEEDVVITISHLGYIKRTSATEFRAQRRGGRGAKGSKA-EEDFIEHLFVASSHHTMLFFTEKGRCYWLNVYEIPEGDKTSKGRAIQNLIQLPPDD
KIRAIIDIQE--KSHNIVLATKKGIIKKTALEDFSR-RTTGVNAITIVEGDELLVAKLTNGNSEIMMAVKSGRAIRFA---VRATGRGAIGVSGIDVDD-
-DVIGMICVSKSRSVLVVSEKGYGKRTALE-YPITNRGGKGVKTLNVTE-KTGSLVGMLDVA-KEDLMITCKSGMTIRMPADGISELGRNTQGVKLIRLD
-GEIAAITKLD-
>tr|A0A0C1LEG1|A0A0C1LEG1_9SPHI DNA gyrase subunit A OS=Flavihumibacter solisilvae GN=gyrA PE=3 SV=1
ILDFIPEEDVVITISHLGYIKRTSATEFRQQRRGGRGALGGKT-DEDYIEHIFVASTHHTMLFFTEKGRCYWLKVYEIPEGEKNSKGRAIQNLMQLPPDD
KVRAIIDVSD--QQHYILLCTKQGVIKKTLLEDFSR-RQTGVNAITIIEGDQLLDARMTDGSCEIMMAVKSGRAIRFP---VRPTGRGAIGVGGIEVDK-
-DVIGMICVKKEKTVLVVSEKGFGKRTPID-YRITNRGGKGVKTISVTD-KTGPLVGILDVK-SEDLMITCKSGLTIRTGIADIREAGRATQGVKLISLQ
-GEIAAITKLD-
>tr|C7PUW6|C7PUW6_CHIPD DNA gyrase subunit A OS=Chitinophaga pinensis (strain ATCC 43595 / DSM 2588 / NCIB 11800 / UQM 2034) GN=gyrA PE=3 SV=1
MEDIIAEEDVVITISHLGYIKRTSAYDYRQQKRGGRGALGGKT-EEDYIEHLFVASTHHTMLFFTEKGRCYWLKVYEIPEGEKSGKGRAIQNLINLPTDD
KIRAIIDIKG--SSHYIVLCTANGIIKKTLLEDFSR-RQNGVNAITINEGDQLLEAKLTNGNSQIMMAIKSGRAIRFP---VRDTGRGAIGVRGIEVDD-
-DVVGMICVNKTRTVLVVSEKGFGKRTDIEEYRITNRGGKGVKTINITE-KTGSLIAILDVT-KDDLMITCKSGITIRMAVADIREAGRATQGVRLIRLD
-SEIAAVARLD-
>tr|A0A0E9N7F0|A0A0E9N7F0_9SPHI DNA gyrase subunit A OS=Flavihumibacter petaseus NBRC 106054 GN=gyrA PE=3 SV=1
ILDFIPEEDVVITVSHLGYIKRTSATEYRQQRRGGRGAIGSKT-DEDFIEHIFVASTHHTLLFFTEKGRCYWLKVHEIPEGEKNSKGRAIQNLMQLPSDD
KVRAVIDIPE--EKHYIILCTKQGIIKKTELADFSR-RQTGVNAITIVEGDQLLDARLTDGDCEIMMAVKSGRAIRFP---VRPTGRGAIGVTAIEVDT-
-DVIGMICVKTDKTVLVVSEKGFGKRTPID-YRVTNRGGKGVKTINITD-KTGPLVGILDVT-KQDLMISCKSGLTIRTAISDIREAGRATQGVKLINLQ
-KAIASLTTIR-
>tr|W0EZE1|W0EZE1_9SPHI DNA gyrase subunit A OS=Niabella soli DSM 19437 GN=gyrA PE=3 SV=1
IKDLIKEEDVIITISHLGYIKRTPADEYRAQRRGGRGVMGGKT-DEDYIEHLFVASTHHTLLFFTEKGRCYWLNAYQIPEGEKTGKGRAIQNLMQLPPDD
KIRAIIDVQK--ASHNIVLCTKKGIIKKTALADFSR-RQTGVNAITINEGDQLLEAKMTDGKSEIMMAVKSGRAIRFS---VRPTGRGAIGVGGIEVDE-
-DVIGLICLAADKSVLVVSEKGYGKRTKVE-YRFTNRGGKGVKTINVTE-KTGSLVGLLDVD-TQDLLITCKSGITIRMPISGISELGRATQGVKLIRIE
-DQIAAISKVD-
>tr|K2DPL5|K2DPL5_9BACT DNA topoisomerase (ATP-hydrolyzing) (Fragment) OS=uncultured bacterium (gcode 4) GN=ACD_24C00470G0003 PE=4 SV=1
DEDLVVQENCIIAISENGYIKRLKEDAYRKQARGG-G--TQA--ED-QVSTIRICNTHDYAFFFTNKGRVYKMRIWDIPES-RIAKGTALVNFL-NSE-E
K--TFLALS--NGKGYLVFSTEKGSVKKTSLEEFAN-R-SGILAINLP--DYLTR---S---DDILLTTSQGQSI------VRSMGRAASGVTGIKLTK-
DDVVGMVVISKKDNLIVVTEGGYGKRTPL-EYK-QGRGGTGILTY---TEKTGKI-AAQAMP-ETDILIATLSGKVIRLST-QIPT-GR---GVRLIRLA
G-KVISVAFLD-
>tr|A0A0G0YBY6|A0A0G0YBY6_9BACT DNA gyrase subunit A OS=candidate division WWE3 bacterium GW2011_GWE1_41_27 GN=gyrA PE=3 SV=1
DEDLIIDEPCIVTISESGYIKRLKEDTYKKQGRGG-G--VQG--ED-SVDTIRTCATHDWALFFTNTGRVYKMRVWDIPES-RTAKGTPLVNFL-STS-E
R--AFLTIT--EEKGFVFFVTEKGVVKRTGMPEFSN-R-SGILAIKLG--DNLAF---TD---DVLITTTMGQSI------VRDMGRAAGGVTGIKLSK-
-GVVGSVIIPNNIDLLVVSDKGYGKRTKT-EYK-QSRAGSGILTY---TDKTGHV-SARAVN-GSDVLLATNSGKVLRIGA-NVPV-GR---GVKLMKLD
--ALTSAAVLE-
>tr|A0A0G1NK22|A0A0G1NK22_9BACT DNA gyrase subunit A OS=candidate division WWE3 bacterium GW2011_GWC2_44_9 GN=gyrA PE=3 SV=1
DEDLVPEELCIVTISQSGYIKRMKKDTYRKQGRGG-G--SQT--DD-VVTTIRTCNTHDFALLFTNKGKVYKMRVWEIPEL-RTARGTSLANFL-SSD-E
T--AFLTLD--NASGYIFFATTHGTVKKTTITEFSN-R-SGIQAIGMD--DTLLK---TD---DVLLVTSQGQSI------VRSMGRQASGVTGVKLAK-
-QVVGIEILSKKCDLLVLTEKGYGKKSSI-EYK-QNRAGSGVLTY---TERVGKS-VARIID-NYDMLVSTQNGIIIRVDA-KIPT-GR---GVRIIKLE
--CVSSIAFLN-
>tr|K2EMV9|K2EMV9_9BACT DNA gyrase subunit A OS=uncultured bacterium (gcode 4) GN=gyrA PE=3 SV=1
DEDLVVDETCIITISENGYIKRLKEDTYKKQGRGG-G--TQA--ED-EVSSITTCSTHDYAFFFTNTGKVYKLRIWEIPES-RTAKGTALVNFL-NSN-E
K--EFVTMK--KGDGFVVFVTDSGQVKKTSLEEFAN-R-SGIVAIKLA--DYLST---SD---DILLTTSQGQSI------VRPMGRAAAGVTGIKLAK-
-KVVGTIIIPSKLDLMVVTARGFGKRTPI-EYK-QKRGGSGILTY---TEKTGAV-TAREQT-ETDFLIATTSGKVIRLSS-QVPQ-GR---GVRLIRID
--RVTSVALLN-
>tr|A0A0G1PAN4|A0A0G1PAN4_9BACT DNA gyrase subunit A OS=candidate division WWE3 bacterium GW2011_GWA1_46_21 GN=gyrA PE=3 SV=1
DEDLVANEVCIVSLSKSGYIKRMKPDVYKKQGRGG-G--SQT--ED-IVDEIKTCQTHDTALFFTNKGKVYKLRIWEIPES-RQAKGTALVNFL-NSE-E
R--AFLPVA--AGEGFVVFGTKQGVVKKTAIEEFAN-R-NGILAIKLG--DDLVW---SD---EVMLVTANGQSI------VRAMGRAAAGVTGIRIKA-
-KVIGMEVLSKGGNLIALTQKGYGKKTPL-EYK-QNRGGSGLLTY---TDKTGTV-AIRAQS-AADALIASTSGKVIRLGE-QIPK-GR---GVRLIRLE
--SVGSVAFLA-
>tr|M1LUD7|M1LUD7_9PROT DNA gyrase subunit A OS=Candidatus Kinetoplastibacterium crithidii TCC036E GN=gyrA PE=3 SV=1
TEDLIVPNDMVVTLSYNGYLKSQPLSEYHAQKRGGHGQATS-IKDDDWIEHLFIANSHEYLLFFSDLGRVYWIKVWETPQGSRGSKGKPVINLFPLS-NE
KITVILPVKDF--DLYVFMATAKGTVKKTPLSDFSNPRKNGIIAVGLNDGDYLIGAELTNGDYDVMLFSDSGKAVRFNEKDVRSMGRSARGVRGMILG--
KNVVSLLVSNN-KSVLIATENGFGKRTSIKQYTVHNRSTKGMIAIQNSK-RNGKVIGAVLVNPNDEIMLITTAGVLVRTRIAEIRNMGRITQGVTLINIA
KGYLSKVRKVV-
>tr|A0A081G3T0|A0A081G3T0_9ALTE DNA gyrase subunit A OS=Marinobacterium sp. AK27 GN=gyrA PE=3 SV=1
VADLITEEDMVVTISHGGYAKTQPISAYQAQRRGGKGSATA-MKDEDFIEHLLIANTHDTILCFTNHGKVYWRKVYEIPPASRTSRGRPVVNILPLA-DE
RISAILPVKEFDSERFIFLATANGTVKKTPLEAFSRPRSTGLIALEIVEGDRLIGASITNGNDDVMLVTSAGKAIRFNENDVRAMGRTARGVRGVRMEEA
S-VISLIIPR-GARVLTASANGYGKQTAVEDFPLRGRGGQGVIAMQCTD-RNGDLAGAVQVLDGDDVMLISDRGTLVRTRSEEISTLGRNTQGVMLIRLA
EGKLSGLARIE-
>tr|E1QGC8|E1QGC8_DESB2 DNA gyrase subunit A OS=Desulfarculus baarsii (strain ATCC 33931 / DSM 2075 / VKM B-1802 / 2st14) GN=gyrA PE=3 SV=1
LEDMIAEEEMVVTLSHGGYIKRTPTSLYRAQRRGGKGSRGMAT-DEDFVEDLFTASTHSYLLIFTDAGRLYWLKVHEIPQAGRASRGKAIVNLVQMLP-E
SVSTVLAVR----GRQVIMATQKGVIKKTELMSFSR-RAGGIIAINLAEGDHLVSAR-TDG-MEVFLATRQGQAIRFHE--VRSMGRAAAGVKGIDVE--
DQVVAMEAVAGAPTMLTITENGFGKRTRMDEYPARNRAGKGVITIKTT-T-NGHVVSALVVGD-DEVMLITDVGKVIRMKVGGISVIGRNTQGVKLIDLE
-GRLVAVARLA-
>tr|A0A063Y5A2|A0A063Y5A2_9GAMM DNA gyrase subunit A OS=Nitrincola lacisaponensis GN=gyrA PE=3 SV=1
VADLITEEDMVLTISHSGYAKTQPLDAYQAQRRGGKGSATA-MKDEDFIEHLLIANTHDTVLCFTSRGKVYWLKVYEIPPASRASRGRPLVNILPLE-GE
RVNTILPVKEFDEDRFIFMATAQGTVKKTPLQSFSRPRSTGLIALDIVEGDCLVGAAITNGNDDVMLVTSAGKAVRFNEQDVRPMGRTARGVRGVRMPEA
S-VISLIIPQ-DGKILTASEKGYGKQTAVEDFPLRGRGGQGVIAMQCTE-RNGALAGAVQVFNGDGVMLISNRGTLVRTRTDEISVLGRNTQGVMLIRLS
EDKLVGLARIE-
>tr|Q2BK80|Q2BK80_NEPCE DNA gyrase subunit A OS=Neptuniibacter caesariensis GN=gyrA PE=3 SV=1
VADLITEEDMVVTISHGGYAKTQPLTDYQSQRRGGKGSAAA-IKDEDFIEHLLIANTHDTILCFTDRGKVYWLRVFEIPVASRTARGRPIVNILPLD-GE
RISTILPVGGYEEDKFIFMATASGTVKKTALTNFSRPRASGLIALDLLDDDHLIGAAITNGEDDVMLMTSAGKSMRFREEDVRPMGRTARGVRGVKMDDV
K-VISLIIPQ-GGKILTASENGYGKKTAVDDFPVKGRGGQGVIAQQCSD-RNGSLAGAVQVFDGDDVMLISDQGTLVRTGGDEISELGRNTQGVTLIRVA
DDRLVSVARIE-
>tr|W9V6B4|W9V6B4_9GAMM DNA gyrase subunit A OS=Nitrincola sp. AK23 GN=gyrA PE=3 SV=1
HADLITEEDMVLTVSHNGYAKTQPITDYQSQRRGGKGSATA-MKDEDFIEHLLIANTHDTVLCFTNKGKVYWLKVYEIPPASRASRGRPMINILPLD-DE
CITTLLPVKEFDENRYIFMATAMGTVKKTPLQSFARPRSTGLIALDTVDGDRLIGASITNGNDDVMLVTSAGKAVRFNEQDVRPMGRTARGVRGVKMNET
R-VISLIIPQ-GGNVLTASEKGYGKQTAVEDFPLRGRGGQGVIAMQCTD-RNGALAGAVQVFAGDGMMLISDKGTLVRTRTDEISVLGRNTQGVMLIRLS
DEKLVGIARIE-
>tr|A0A0G1C0G9|A0A0G1C0G9_9BACT DNA gyrase subunit A OS=Microgenomates (Collierbacteria) bacterium GW2011_GWA2_42_17 GN=gyrA PE=3 SV=1
EEDLIPSEETIVTLTKSGYIKRMPLSTFRTQKRGG-G--SMT--TD-EIQLLTNANTHDRLLVFTSKGKVFALKVWELPES-RISKGQAIINLI-NED-E
T--SILPMP--N--RFLFFTTKAGVVKRTALLKYEN-K-NGLIAIKLQ--DNLVW---TD---HILLVSKDGKSI------VRPTDRDTQGVRGILLK--
-NVISMDVFGPFRDLLIVTEKGMGKRTPL-EYP-QNRSGQGLKVC---TDKTGKA-GALLVD--EVLLITTSQGQAIKLPI-NIPR-GR---GVILMRFA
D-SVAAVTTVS-
>tr|A0A0G1I780|A0A0G1I780_9BACT DNA gyrase subunit A OS=Microgenomates bacterium GW2011_GWC1_44_23 GN=gyrA PE=3 SV=1
EEDLIPAEETIVALTKSGYIKRMPLDTFRSQKRGG-G--AMT--TD-EIHLLTNANTHDRLLVFTSKGKVFSLKVWELPES-RTSKGQAIINLI-NED-E
T--SLLTMS--G--EFLFFTTKTGVVKRTAMSKYEN-K-NGLIAIKLN--DSLVW---TD---HISLVSRDGKSI------VRPTDRDTMGVRGILLK--
-GIISMESFPPFRDYLIVTEHGMGKRTPL-EYP-QNRSGQGLKVS---TDKTGKA-GALLVD--EMLLITTSQGQAIKLPV-NIPR-GR---GVILMRFA
E-SVAAVTVIS-
>tr|A0A0G1PLF7|A0A0G1PLF7_9BACT DNA gyrase subunit A OS=Microgenomates (Collierbacteria) bacterium GW2011_GWA2_46_26 GN=gyrA PE=3 SV=1
EEDLIPAEETIVALTKSGYIKRMPLATFKTQKRGG-G--SMT--TD-EIHLLTNANTHDRLLVFSSKGKVFSLKVWELPES-RISKGQAIINLI-NDD-E
T--SILPLT--N--DCLFFTTKKGIVKRTVLSKYEN-K-NGLIAIKLT--DSLVW---TD---HILLVSRDGKSI------VRPTDRDTMGVRGILLK--
-GIISMESFAEFRDLLVVTEKGMGKRTPI-EYP-QNRSGQGLKVS---ADKTGKA-GALLVD--EVVLITTSQGQAIKLPV-NIPR-GR---GVILMRFA
E-SIVAVTVVS-
>tr|A3J5N9|A3J5N9_9FLAO DNA gyrase subunit A OS=Flavobacteria bacterium BAL38 GN=gyrA PE=3 SV=1
IEDLIADESVVITISHAGYIKRTSLSEYKTQNRGGVGQKSAGT-DQDFLEHLFVATNHQYLMYFTQKGKCYWMRVYEIPEGTKASKGRAIQNLINIESDD
KVKAFICTQK--KSHNLIMVTKQGQVKKTSLEKYSK-RVNGVAAITIKEGDELLGAKLTNGSSQVLIAGKSGKMVRFE---TRPMGRTASGVRGITLAE-
-DVIGIVTVNKETQILVVTENGYGKRTKLVVYRITNRGGKGVKTLNITE-KTGALIAINNVT-DDDLMIINKSGLTIRMMVSDLRVMGRATQGVKLINIK
-NSIAAVTKVL-
>tr|X8H097|X8H097_9FIRM DNA gyrase subunit A OS=Shuttleworthia sp. MSX8B GN=gyrA PE=3 SV=1
AEDLIPVTHPIITFTKFGYIKRMSADNFRAQHRGGKGIKGMET-KDDYIVELIQTRSHNFLYFFTNKGRVYRLKAYEIPES-RTARGTAIVNLLQLMPDE
TITSMIPVV-G-EDKYLFMATQRGIVKKTRLREYENIRKSGLAAINLRDEDRLIEVKLTDDTDEVMLFTRFGQCVRFH---VRGTGRSTMGVIGINLS--
-CVIAMQLASQGESLVLVSQRGLGKCTLTEEFP-HHRGGKGVKCYKITE-KTGDLVGVKSVD-DNQLMLINRAGTIIRINIADTA-LGRITSGVKLIDLK
-DAS--ISVVQ-
>tr|D7DHN5|D7DHN5_METV0 DNA gyrase subunit A OS=Methylotenera versatilis (strain 301) GN=gyrA PE=3 SV=1
LEDFITPQDVVVTLSHTGYVKSQPLDEYRAQRRGGRGQAAQ-TKEDDFIDKMFVANTHDYILCFSSRGQVYWLKVYEVPQGSRTGRGKPIVNLFPLE-GE
KINAILSVKEF--NHFIFMATSLGTVKKTPLSDFANPRKSGIIAINLDEGDFLIGAEITNGANDVILVSNGGKAVWFTE-DVRSMGRATRGVRGMKLA--
DNVLSLLIADNQQSVLVATENGYGKRTVLADFRHSGRGTQGVKAIAISE-RNGLVVAAKLVNEDDEIMLITTGGVLIRTRVKEIRELGRATQGVTLINLG
EGKLSGLEKIV-
>tr|O86092|O86092_METSS DNA gyrase subunit A OS=Methylovorus sp. (strain SS1 / DSM 11726) GN=gyrA PE=3 SV=1
LEDLITPQDVVVTLSHTGYVKSQPLDEYRAQRRGGRGQATA-TKEDDFIDKMFVANTHDYILCFSSRGRVYWLKYTKCRKAAA-SAVQAYRQPLPAG-GR
EDQCHLPVKEF--NHFIFMATAQGTVKKTALVEFSNPRRAGIIAINLDEGDYLIGAEVTNGANDIVLVSNGGKAVWFDE-DVRAMGRNTRGVRGMKLM--
PKVISLLIAEDKQTVLVATENGYGKRTVLSDFRHSGRGTQGVKAIATSD-RNGSVVGARLVNDEDEIMLITTGGVLIRTRVKEIRELGRATQGVTLINLG
ENKLSGLEKVV-
>tr|A0A0D6EVS3|A0A0D6EVS3_9PROT DNA gyrase subunit A OS=Candidatus Methylopumilus planktonicus GN=gyrA PE=3 SV=1
TEDLITPEDVVVTLSHTGYIKSQVLDEYRAQKRGGRGQAAT-TKDDDFIDKMFVANTHDNILCFSSRGQVYWLKVYEVPQGSRTSRGKPIVNLFPLQ-GE
KINAILPIKEF--KHYIFMATALGTVKKTPLTDFSNPRKSGIIAINLDDNDFLIGAEITDGSNDIVLVSNGGKAVWFDE-DVRSMGRNTRGVRGMKLQ--
EDVLSLLIASDQQSMLVATENGYGKRTVLSDFRHSGRATQGVKAIQVSE-RNGLVVAAKLVNDEDEIMLITTGGVLIRTRVSEIRELGRATQGVTLINLG
ENKLSGLEKIV-
>tr|T1BQQ5|T1BQQ5_9ZZZZ DNA gyrase subunit A OS=mine drainage metagenome GN=B1A_06053 PE=3 SV=1
IEDLITPEERVVTLTHGGYIKSQPVADYRAQRRGGRGQATT-TKEDDFIERLFVANTHDHILCFSTRGRVYWLRVYQVPVGNRTSRGKPIVNLLPLE-GE
KITAVLPVKTF--EHYVFMATSFGTVKKTSLSDFSRPRTAGIIALDLDAEDYLVGVAITDGQHDVMLFSDEGKAIRFAE-DVRPMGRNAHGVRGMRLP--
EGIIALLVAENRQSVLTATENGFGKRTSVLEYTRHGRGGQGIIAIQTSA-RNGKVVSAALVDPEEELMLITTGGVLIRTRVQEIREMGRATQGVTLIALD
EGKLVCLTRAD-
>tr|A0A0B7IXG0|A0A0B7IXG0_9PROT DNA gyrase subunit A OS=Candidatus Methylopumilus turicensis GN=gyrA PE=3 SV=1
LEDLITPQDVVVTLSHTGYIKSQPLEEYRSQRRGGRGQAAA-TKEDDFIDKMFVANTHDYILCFSSLGQVYWLKVYEVPQGSRTSRGKPIVNLFPLS-GE
KINAILPVKEF--NRFVFMATAMGTVKKTALNEFSNPRKSGIIAINLDDGDYLIGAEITNGTQDIVLVSNGGKAVWFDE-DVRAMGRNTRGVRGMKIT--
KDVLSLLVAENQQTVLVATENGFGKRTVLADFRHSGRGTQGVKAIAISE-RNGLVVAARLVNDDDEIMLITTGGVLIRTRVKEIRELGRATQGVTLINLG
DGKLSGLEKVV-
>tr|Y0KGW6|Y0KGW6_9PROT DNA gyrase subunit A OS=Methylophilaceae bacterium 11 GN=gyrA PE=3 SV=1
LEDLISPQDVVVTLSHTGYIKSQPLDEYRAQKRGGRGQAAA-TKEDDFIDKMFVANTHDYILCFSSLGQVYWLKVYEVPQGSRISRGKPIVNLFPLE-GE
KINAILSVKEF--NHFIFMATAQGTVKKTALTEFANPRKSGIIAIKLDDGDYLIGAEITNGKNDIVLVSNGGKAVWFTE-DVRPMGRATRGVRGMKLG--
AKVLSLLIAENQQSVLVATENGYGKRTVLSEFRHSGRGTQGVKAIAISE-RNGTAIAAKLVREDDEIMLITTGGVLIRTRVKEIRDMGRAAQGVTLINLG
EGKLSGLEKIV-
>tr|A0A0R2T199|A0A0R2T199_9PROT DNA gyrase subunit A OS=Methylophilales bacterium BACL14 MAG-120910-bin43 GN=ABS06_04220 PE=4 SV=1
IEDLIAPQDMVVTLSNSGYIKAQVLDDYRAQKRGGRGQAMG-TKEDDFIEQMFVANSHDNILCFSSRGQVYWLKVYEVPQGSRVSRGKPIVNLFPLM-GE
KINAILAVKDF--DEFIFMATAKGTVKKTPLSDFSNPRKSGIIAIKLANGDYLVGAGVTNGEQDIILISSGGKAVWFDE-DVRSMGRNAAGVRGMKLP--
ATVLSLLIASSQESVLVATENGYGKRTVLSEFRKSGRGTQGVKAIQVSD-RNGIVVAAKLVGDHDEIMLITTGGVLIRTRVSEIRELGRATQGVTLINLS
DGKLSGIEKIV-
>tr|A0A0H4J3M6|A0A0H4J3M6_9PROT DNA gyrase subunit A OS=Methylophilales bacterium MBRSG12 GN=gyrA PE=3 SV=1
IEDLIAPQDMVVTLSHTGYIKAQALDDYRAQKRGGRGQATA-TKDDDFIDQMFVANSHDNILCFSSRGQVYWLKVYEVPQGSRVSRGKPIVNLFPLM-GE
KINAILTVKEF--NEYIFMATAKGTVKKTPLSDFSNPRKSGIIAIKLDNGDYLIGAGITKGENDIVLVSNHGKAVWFGE-DVRSMGRNARGVRGMKLT--
DGVLSLLIAENAQSVMVATENGYGKRTQLSEFRRSGRGTQGVKAIQVSD-RNGQVVGAKLVDDHDELMLITTGGVLIRTRVSEIRELGRATQGVTLINLG
DDKLRGLEKVA-
>tr|C6WVE9|C6WVE9_METML DNA gyrase subunit A OS=Methylotenera mobilis (strain JLW8 / ATCC BAA-1282 / DSM 17540) GN=gyrA PE=3 SV=1
LEDLIAPQDVVVTLSHTGYIKSQPLDEYRAQKRGGRGQAAA-TKEDDFIDKMFVANTHDYILCFSNRGRVYWLKVYEVPQGSRTSRGKPIVNLFPLE-NE
KINAILSVKSF--NHFIFMATSLGTVKKTALTEFANPRRSGIIAINLDEGDYLIGAEITNGSNDVVLVSNGGKAVWFDE-EVRQMGRATRGVRGMKLA--
EDVLSLLIASNQQTVMVATENGYGKRTVLADFRRSGRGTQGVKAIAVSE-RNGLVVAAKLVSDEDEIMLITTGGVLIRTRVSEIRELGRATQGVTLINLG
EGKLSGIEKIV-
>tr|Q1H0N1|Q1H0N1_METFK DNA gyrase subunit A OS=Methylobacillus flagellatus (strain KT / ATCC 51484 / DSM 6875) GN=gyrA PE=3 SV=1
LEDLITPQDVVVTLSHTGYVKSQPLEEYRAQRRGGRGQAAA-TKEDDFIDKMFVANTHDYILCFSSRGRVYWLKVYEVPQGSRVSRGKPIVNLFPLE-GE
KINAILPVKEF--NHFVFMATAKGTVKKTALTEFSNPRRSGIIALNLDDGDYLIGAEVTNGVNDIVLVSNGGKAVWFDE-DVRPMGRAARGVRGMKLQ--
GKVISLLIADNKQTVLVATENGYGKRTVLADFRHSGRGTQGVKAIATSE-RNGIVVGARLVGDDDEIMLITTGGVLIRTRVKEIRELGRATQGVTLINLG
EGKLSGLEKVV-
>tr|D6YW60|D6YW60_WADCW DNA gyrase subunit A OS=Waddlia chondrophila (strain ATCC VR-1470 / WSU 86-1044) GN=gyrA PE=3 SV=1
IEDLIANEPAIITISQDDYIKRMPVDTFREQRRGGTGVVGFNQKEEDVLKGLYVANTHDHLLVFTNLGRCYWLKVWQIPEGSRRSKGKPLVNLLSDRSEE
SIATVLQ---FGD-RYVLMATRNGIVKKTPIDAFSNPRRNGIWAIDIVEGDELEGAR-VEGEQQVMLFTHNGMAVRFDH--VRSMGRMARGVKGVSLK--
-NRVVGCE---NETVLIVCENGFGKRSTVSDFRQTNRGGVGVRSI--SR--NGKVVGAVCITDDDGLLMMSSSGQTLRISMKDLRVMGRNTQGVKLANLR
-DILVAIQKVE-
>tr|G1FGT8|G1FGT8_9CHLA DNA gyrase subunit A OS=Estrella lausannensis GN=gyrA PE=3 SV=1
MEDLIADTEVLITISEDDYIKRMPIDTFREQKRGGQGVAGVKL-EDDAIKSLYTASMHDYLLIFTTHGRCLWLKVWQIPEGSRTAKGKPLINLLADQENE
RIATILKTR-F--A-DIIMATEKGVVKRSELSHFSNPRKRGIIALAIDEGDALVAARLIGKSEKAMLFTYHGMAVRFDE--VRPMGRQARGVKGATLKE-
-RVIALEVVKGSESILVVCENGFGKRSQVEDFRETNRGSSGVRSI--SE-RNGNVIAALRVDDNDSIVLMSASGQTVRISMKDVRVMGRNTQGVKLANVK
-GSLVSVQKLQ-
>tr|A0A078L4U7|A0A078L4U7_9CHLA DNA gyrase subunit A OS=Chlamydia sp. 'Rubis' GN=gyrA_2 PE=3 SV=1
MEDLIANEAVIITISEDDYIKRMPMDTFKEQKRGGQGIAGMQL-EDDAIKGLYVASTHDYLLIFTNLGRCYWLKVWQIPETGRKSKGKALINLLEDRPDE
KIATILKVS-F--S-CILMATKKAVVKKTLLSEFSNPRRKGIWALDVDEGDEVMATRLVHEGQQVMLFTHQGMAVRFDE--VRPMGRMARGVKGATLKD-
-YIVGCEVVNGNETVLVVCENGFGKRSLVEDFRQTNRGGVGVKSI--SE-RNGNVVGALCVTDEDGMLMMSSTGQTVRINMNDLRVMGRNTQGVKLANLR
-GYLVAVQKIE-
>tr|Q6MCA1|Q6MCA1_PARUW DNA gyrase subunit A OS=Protochlamydia amoebophila (strain UWE25) GN=gyrA PE=3 SV=1
MEDLIANEPVIITISQDDYIKRMPVNTFREQRRGGQGVTGMQL-EEDVIKGLYVATTHDYLLIFTNLGRCYWLKVWQIPETGRKSKGKPLINLLEDRPEE
KIATIQRVS-F--A-CILMATKRAVVKKSLLNEFSNPRRKGIWALDIDEGDELVAARLVKPEQQVMLFTHQGMAVRFEE--VRPMGRTARGVKGATLRE-
-YIVGCEVVNGDESILVVCENGFGKRSQVDDFRQTNRGGVGVRSI--SE-RNGKVIGALCVTDEDGMVMMSATGQTVRINMNDLRVMGRNTQGVKLANLK
-NYLVAIQKLQ-
>tr|S4TLL1|S4TLL1_9CHLA DNA gyrase subunit A OS=Neochlamydia hartmannellae GN=gyrA PE=3 SV=1
MEDLIANESVIITISEDDYIKRMPMNTFREQRRGGQGVAGMQM-EDDTIKGLYVASTHDYLLIFTSLGRCYWLKVWQIPESSRKSKGKPLINLLEDQPNE
KIATIQRVS-F--S-CILMTTRKGVVKKSALNNFSNPRRKGIWALDLDEGDEVVAARLVNTGQQVMIFTYQGMAVRFAE--VRPMGRMARGVKGVTLKE-
-YVVGCEVVNGDETILVVCENGFGKRSLVEDFRQTNRGGVGVRSI--SE-RNGNVVGALCVADTDGMVMMTSSGQTIRISMRDLRVLGRNTQGVKLANLR
-GFLVAIQKVS-
>tr|A0A0C1K079|A0A0C1K079_9CHLA DNA gyrase subunit A OS=Neochlamydia sp. TUME1 GN=gyrA PE=3 SV=1
MEDLIANEPVIITISEDDYIKRMPMDTFREQRRGGQGVAGMQM-EDDTIKGLYVATMHDYLLIFTNLGRCYWIKVWQIPESSRKSKGKPLVNLLEDQPNE
KIATIMRVS-F--A-CILMATRKGVVKKSELSHFSNPRRKGIWALDVDEGDEVVAARLVKEEYQVMIFTHRGMAVRFAE--VRPMGRMARGVKGVSLRE-
-YVVSCEVVKGDETILVVCENGFGKRSLVEDFRQTNRGGVGVRSI--SE-RNGNVVGALCVADTDGMVMMTASGQAIRISMRELRVLGRNTQGVRLANLR
-NYLVAIQKVK-
>tr|F8KZS0|F8KZS0_PARAV DNA gyrase subunit A OS=Parachlamydia acanthamoebae (strain UV7) GN=gyrA PE=3 SV=1
MEDLIANESVIITISEDDYIKRMPVDTFREQRRGGQGIAGMHL-EEDAIKGLYVASTHDYLLIFTNLGRCYWLKVWQIPETGRKSKGKPLINLLEDRPDE
KIATVLRVS-F--A-YILMATKKGIVKKTELSEFSHPRRKGIWALDIVEGDEVVTARLVSDSQQIMLFTYHGMAVRFDQ--VRPMGRTARGVKGVTLKD-
-YVVGCEAVNGTETILIVCENGFGKRSNVEDFRQTNRGGVGVRSI--SE-RNGNVVGALCVTDEDGMVMMSAQGQTVRITMKDLRVMGRNTQGVKLANLK
-GYLVAIQKLE-
>tr|G1FGT2|G1FGT2_9CHLA DNA gyrase subunit A OS=Criblamydia sequanensis GN=gyrA PE=3 SV=1
MEDLIADESVLITISEDDYIKRMPIDTFKEQKRGGLGVAGVQL-EDDAIKGIYVASMHKDLLIFTTLGRCYWLKVWQIPEASRKAKGKPLINLLEDKEGE
KIATVLSTQ-F--A-CIIMATEKGVVKKTGLDQFSNPRRKGIYALSIDEGDRLIAARLVKKDQQVMLFTHHGMAVRFDE--VRPMGRTARGVRGATLKA-
-RIVGVEVVNGNETVLVVSENGFGKRSNVEDFRQTNRGGSGVRSI--SE-RNGNVVAALCVEDTDGIVMMSSLGQTIRISMQNVRVMGRNTQGVKLVNLK
-DTLVTVQKVA-
>tr|B0B0K4|B0B0K4_STAIN DNA gyrase subunit A OS=Staphylococcus intermedius GN=gyrA PE=3 SV=1
DEDLIPEEQIVITLSHNNYIKRLPASTYRAQNRGGRGVQGMNT-EDDFVSQLVTTSTHDHVLFFTNKGRVYKLKGYEVPELSRQSKGIPIVNAIELDQ-E
VISTMIAVK---EEDFLVFVTKKGLIKRSALSNFNR-NRNGKIAIKFRDDDELIAVR-TDG-KHILIGTAQASLIRFKE--VRAMSRIAAGVKGIRLR--
-GVIGLDVADDKDEILVVTEKGYGKRTSIEDYRLSNRGGMGVKTAKLT-E-NGRLVCITTVED-EDLMVVTNQGVIIRMEVSNISVNGRMAQGVRLIRLD
E-YVSTVAKVK-
>tr|A0A0C2DIB7|A0A0C2DIB7_9STAP DNA gyrase subunit A OS=Salinicoccus roseus GN=gyrA PE=3 SV=1
DEDLIPEEQIVVTLSHNNYIKRLPSSTYRAQHRGGRGVQGMNT-EDDFVSQIVTMSTHDYIMFFTNKGRVYRLKGYEIPELSRQSKGIPIVNMLEIDK-E
VISTMIGVK---EDKFLVFATKNGLVKRSTLDNFER-NKNGKIAISFRGDDELLAVR-TDG-KEVILGTRNANLIRFPE--IRTMGRTAAGVKGIKLR--
-DVIGLDVLSE-QSILVVTENGYGKCTPEAEYRITRRGGMGVKTANLT-E-IGKLVYIAAIDD-EDLMIVTNHGVIIRLVMEEVSTTGRNTQGVRLIKMT
D-QVATVAKVK-
>tr|A0A0D6XSL9|A0A0D6XSL9_9STAP DNA gyrase subunit A OS=Staphylococcus microti GN=gyrA PE=3 SV=1
DEDLIPEEQIVISLSHNNYIKRLPVSTYRAQNRGGRGVQGMNT-EDDFVSQLVTTSTHDDVLFFTNKGRVYKLRGYEVPELSRQSKGIPVVNAIDLEA-E
VISTMIAVK---EDDFLVFVTNKGLVKRSALSNFNR-NKNGKIAIKFRDDDELVAVR-TDG-KHILIGTSQASLIRFKE--IRAMSRIASGVKGITLR--
-DVIGLGVADETDEILVVTEKGYGKRTPIGEYRLSRRGGMGIKTANIT-E-NGKLVCIATVED-EDIMVVTDHGVIIRMEVEDISVNGRNTQGVRLIRLD
D-FVSTVAKVK-
>tr|G2GWY6|G2GWY6_9ENTR DNA gyrase subunit A OS=Candidatus Regiella insecticola 5.15 GN=gyrA PE=3 SV=1
NEDLINQEDVVVTLSHQGYVKYQPLTDYEAQRRGGKGSAA-RIKGEDFIDQLLVANTHDTILCFSSKGSLYWMKVYQLPEASRSARGRPIVNLLPLK-NE
RITAIL--P--DAGHHVFMATACGIVKKTALDCFSR-RKDGIIAINLNEGDELIGVALTDGN-EVMLFSTDGKAVRFSESKVRSVGRKAAGMRGIKLN--
-DLVSLIIPQKEGEILTITENGYGKRTLAEEYPTKGRATKGVLSI--SE-RNGNVVAAIQVM-SDQIMIITDAGTLVRTRVSEINVQGRNTQGVRLIRTA
-NHVVGLQRVA-
>tr|R8APA4|R8APA4_PLESH DNA gyrase subunit A OS=Plesiomonas shigelloides 302-73 GN=gyrA PE=3 SV=1
IEDLINQEDVVVTLSHEGYVKYQPLTEYEAQRRGGKGSAT-KMKEEDFIERLLVANTHDTILCFSSRGRLYWLKVYQLPLASRGARGRPIVNLLPLE-NE
RITAIL--P--ADDQYIFMATANGTVKKTPLTDFSR-RSAGIIAVNLNDDDTLIGVDLTHGNDEVMLFSAEGKVVRFAEDQVRPMGRTATGVRGIKLS--
-QVVSLIVPKGDGEILTVTANGYGKRTASAEYPTKSRATQGVISI--SE-RNGLVVGAVQVE-NDQIMIITNAGTLVRTRVKEVSVVGRNTQGVTLIRTS
-EQVVGLQRIL-
>tr|A0A077PM47|A0A077PM47_XENBV DNA gyrase subunit A OS=Xenorhabdus bovienii str. kraussei Quebec GN=gyrA PE=3 SV=1
IEDLINQEDVVVTLSHQGYVKYQPLSDYEAQRRGGKGSAA-RIKEEDFLERLLVANTHDTILCFSNKGKMYWMKVYQLPEASRGARGRPIVNLLPLE-EE
RITAIL--P--EDGLNIFMATASGTVKKTKLSEFSR-RSAGIIAVKLNDGDELIGVDLTDGSNEVMLFSAKGKVVRFLEEGVRAMGRTAAGVRGIKLS--
-GVVSLIIPRGEGEILTVTENGYGKRTAQSEYPTKSRATQGVISI--SE-RNGNVIGAIQVE-TDQIMMITDAGTLVRTRVSEVSVVGRNTQGVTLIRTA
-DKVVGLQRVA-
>tr|D2U4I6|D2U4I6_9ENTR DNA gyrase subunit A OS=Arsenophonus nasoniae GN=gyrA PE=3 SV=1
IEDLINQEDVVVTLSHQGYVKYQPLSDYEAQRRGGKGSAA-RIKEEDFIERLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLE-NE
RITAIL--P--DDGHYVFMATASGTVKKTSLKDFSR-RSAGIIAVNLNEGDELIGVDLTAGKNEVMLFSAGGKVVRFAENAVRPMGRTATGVRGIKLH--
-GVVSLIVPRGEGDILTVTENGYGKRTEQSEYPTKSRATQGVISI--SE-RNGNVVGAIQVE-TDQIMMITDAGTLVRTRVAEVSIVGRNTQGVTLIRTA
-DKVVGLQRVV-
>tr|A0A0R1RK28|A0A0R1RK28_9LACO DNA gyrase, A subunit OS=Lactobacillus rossiae DSM 15814 GN=FD35_GL001126 PE=4 SV=1
DEDLIEEEDVIVTLTHNGYIKRLPTTEFKAQHRGGRGVQGMNV-DDDFIEHLISTSTHDRLMMFTNTGKVYAMKGYEIPEYGRTAKGIPVINLLGV-DGE
RIQAVINVK--ESNNYLFFTTVHGVVKRTAVSEFSN-RSNGLKAINLHDGDELMNVS-TDG-QNMIIGTHLGYAVSFAE--VRDMGRSAAGVRGIRLR--
-DVVGADVLKPDSHVLVISEKGYGKQTKASEYPIKGRGGKGIKTVNVT-A-NGPLTGLTTVST-EDIMLVTNKGVMIRFSIDSVSETGRAALGVHLIRID
D-SVATMAKVE-
>tr|I2F081|I2F081_EMTOG DNA gyrase subunit A OS=Emticicia oligotrophica (strain DSM 17448 / GPTSA100-15) GN=gyrA PE=3 SV=1
IEDMIPDDEMLVTISHQGYIKRTPLQEYRTQGRGGTGSRGVKT-DEDYTEHLFAATNHNYLLIFTRKGRLFWMRVFEVPEGSKTSKGRAIQNLINIEADD
KIQAVLNVKS--SNNYIVMCTEDGTVKKTLLEAYSR-RQGGIIAININEGDNLLDVALTNGDNDIVIAARNGKVVRFH---TRPMGRTATGVRGINLE--
-DAIGMVCVSRETQLLVVSDKGYGKRSDVDEYRITSRGAKGVKTLNITE-KTGNLVAIKEVT-DDDLMIITKKGVAIRIKVSDLRVMGRNTQGVKLIRMS
-TDIASVTRII-
>tr|E4RR46|E4RR46_LEAB4 DNA gyrase subunit A OS=Leadbetterella byssophila (strain DSM 17132 / KACC 11308 / 4M15) GN=gyrA PE=3 SV=1
IEDMIPDDEMLVTVTSQGYIKRTNLSEYKSQSRGGTGSRGVKT-DDDYTEHLFMATNHNYLLFFTEKGRLYWLRVFEVPEGNKTSKGRAIQNLINIESDD
KIRAVLNVKS--KNNYIVMCTQNGIVKKTLLEMYSR-RQNGIIAININEGDQLIDVALTNGNDYIIIAAGQGKAVRFH---IRPMGRGATGVKGISLA--
-DAIGMICVNRDAQLLVVSEKGYGKRSDIEDYRITSRGAKGVKTLNMSE-KVGNLVAIKEVT-EDDLMIITTRGIAIRMHVSDLRVMGRNTQGVRLIKLN
-KGIASITRII-
>tr|F8EKT8|F8EKT8_RUNSL DNA gyrase subunit A OS=Runella slithyformis (strain ATCC 29530 / DSM 19594 / LMG 11500 / NCIMB 11436 / LSU 4) GN=gyrA PE=3 SV=
DEDMIADEEMLITISHQGYVKRTPIGEYRTQGRGGVGSRGVTT-DDDFTEHLFSATMLNYLLIFTEFGKLFWLKVYEIPEGSKTAKGRPIQNLINIESGD
KVRAVINVRS--NNNYIIMCTEEGTIKKTLLEAYSR-RANGIAAITINEGDRLLDVALTNGDNQIIIASKEGKAVRFH---VRPMGRTAAGVKGIELGET
-NAIGMLCVSNEKQLMVVSENGYGKRSQIEDYRETNRGAKGVTTLNITE-KVGSLVAIKEVS-SDDLMIINKSGIAIRMSVTEIRVAGRNTQGVRLIKLN
-GEISSVTRIE-
>tr|A0A0Q5T0X4|A0A0Q5T0X4_9BACT DNA gyrase subunit A OS=Dyadobacter sp. Leaf189 GN=ASG33_17945 PE=4 SV=1
DEDMIPDDEMLITISNEGYIKRTPLAEYRTQTRGGVGSRGVKT-DTDFTEHLFSATMLNYLLIFTEYGKLFWMKVYEVPEGSKTSKGRPIQNLISLENGD
SIRSVINVRS--NNNYLIMCTQQGTIKKTLLEAYSR-RANGIIAISINEGDRLLNVALTNGDNDIVIASSAGRAVRFN---VRPMGRTAAGVRGINLTP-
-NVIGMVCINRDAQLLVVSENGFGKRSNIDSYRVTNRGGKGVSTMNATD-KVGKLVAIREVT-QDDLMIITRNGIAIRMSVLDIRLAGRNTQGVKLIRLN
-SEITSVTRIL-
>tr|H1YDQ5|H1YDQ5_9SPHI DNA gyrase subunit A OS=Mucilaginibacter paludis DSM 18603 GN=gyrA PE=3 SV=1
TEDFIEDENVVITISHEGYIKRTPLTEYRTQARGGKGSIGSNS-DADFIEHLLIASNHNYMLFFTESGQCFWLRVFEIPEGTRTSKGRAIQNIINIPKEE
NIKAYIKLTK--ENNFIIMCTRKGVIKKTSLEAYSR-RANGINAININEGDTLLQATLTTGSSEIVMALKSGRAIRFN---VRPMGRTATGVRGITLAE-
-DVVGMIAIDDETTVLVVSEKGYGKRTDIEDYRVTNRGGKGVKTINVTE-KTGQLVAIKGVT-EHDLMIINRSGIIIRISMNQLRTMGRATQGVRLISLK
-NSIASVAQVE-
>tr|H8KVL8|H8KVL8_SOLCM DNA gyrase subunit A OS=Solitalea canadensis (strain ATCC 29591 / DSM 3403 / NBRC 15130 / NCIMB 12057 / USAM 9D) GN=gyrA PE=3 S
IESLIENEDVVITISHAGYIKRTKLTEYRKQARGGRGSMGGST-EEDFIEHLFIAQTHNYMLFFTEKGRCFWLKVYGIPEGSRTSKGRAMQNLIQIESDD
KVKAFITVKN--ESNYIMMCTKQGTIKKTTLEAYSR-RVTGINAITVNEGDQLLEARLTTGNSEILMALKSGRAIRFN---VRPMGRTAAGVRGVTLSV-
-DVVGMIAVEDETNILVVSEKGYGKRSDIEEYRVTNRGGKGVKTINVTE-KTGQLIAIKDVK-SDDLMIINKSGITIRIGVDELRVMGRATQGVRLIKLN
-DEIASVAKIE-
>tr|F0SBI6|F0SBI6_PSESL DNA gyrase subunit A OS=Pseudopedobacter saltans (strain ATCC 51119 / DSM 12145 / JCM 21818 / LMG 10337 / NBRC 100064 / NCIMB 1
TEDFIEDENVVITISHEGYIKRTPLTEYRTQGRGGKGAIGSNS-DEDFIEHIFVASNHNYLLFFTDQGKCYWLRVFEIPEGSRTSKGRAIQNIINIDKEE
KIKAYIKVVK--ENNFIIMCTKKGTIKKTTLEAYSR-RSNGINAININEGDELLEASLTTGNSEIVMALRSGRAIRFN---VRPMGRTATGVRGISLAD-
-DVVGMISIDSESTVLVVSEKGYGKRTDIEDYRVTNRGGKGVKTINITD-KTGQLVAIKSVT-NDDLMIINRSGIVIRIAMDTLRVMGRATQGVRLITLK
-SEIASVTKTE-
>tr|A0A088F002|A0A088F002_9SPHI DNA gyrase subunit A OS=Sphingobacterium sp. ML3W GN=gyrA PE=3 SV=1
MEDFIDDEEIVITISHNSYVKRTPLTEYKRQGRGGRGSIGSST-EEDFTEHIITASAHNYMLLFTESGRCFWLRAFEVPEGSRTSRGRALQNIINIPKDE
KIKAYILVKK--ENNFIIMCTKKGTIKKTSLEAYSR-RANGINAININEGDQLLEACLTSGTSEIVMALRSGRAIRFN---VRPMGRTATGVRGITLGE-
-DVIGMISVDDQTTVLVVSEKGYGKRTDIEDYRVTNRGGKGVKTISVTE-KTGNLVAVKGVN-TEDLMIINKSGIVIRISVEGLRVMGRATQGVRLINLK
-DEIASITKVD-
>tr|F4C701|F4C701_SPHS2 DNA gyrase subunit A OS=Sphingobacterium sp. (strain 21) GN=gyrA PE=3 SV=1
MEDFIDDEEIVITISHEGYVKRTPLTEYRLQARGGKGSLGSTT-EEDFTEHIITASAHNYMLFFTEAGRCFWLRAFEIPEGTRTSRGRAIQNIINIPKEE
KIKAYIKVKK--ENNFIIMCTKGGTIKKTSLEAYSR-RANGINAININEGDQLLEACLTNGNSEIVMALKSGRAIRFN---VRPMGRTATGVRGVTLAP-
-DVVGMISVNTDATILVVSEKGYGKRTDIDDYRVTNRGGKGVKTLNVTE-KTGLLVAIKDVT-NDDLMIINRSGIVIRIAVSQLRVMGRATQGVRLINLK
-NQIASITKVD-
>tr|A0A0Q5MYF2|A0A0Q5MYF2_9SPHI DNA gyrase subunit A OS=Pedobacter sp. Leaf176 GN=ASF92_16860 PE=4 SV=1
MEDFIDDEEVVITISHEGYVKRTPATEFRAQGRGGKGSKGSNS-NEDFIEHMLVATNHNYMLFFTEAGRCFWLRVYEIPEGTRTSKGRAIQNIINIPKEE
KIKAYIKVKK--ENNFIIMCTKQGTIKKTSLEAYSR-RVNGINAININEGDVLLEACLTNGQSEIVMALRSGRAIRFN---VRPMGRTATGVRGVRLAD-
-DVVGMIAVNNEVTVLVVSEKGYGKRTDIEDYRVTNRGGKGVKTINVTE-KTGQLVSIKDVT-SEDLMIINRSGIVIRIPVSALRVMGRATQGVRLISLK
-DEIASVTKID-
>tr|A0A0B8XQJ1|A0A0B8XQJ1_9SPHI DNA gyrase subunit A OS=Pedobacter glucosidilyticus GN=gyrA_2 PE=3 SV=1
TEDFIEDEDVVITISREGYIKRTPLTEYRTQGRGGKGSMGSTS-DEDFIEHIFIASNHNYLLFFTDKGKCYWLRVFEIPEGTRISKGRALQNIINIEKEE
KIRAYIKVVK--ENNFIMMCTKKGTIKKTTLQAYSR-RTNGINAININDGDELLEANLTTGSSEIIMALRSGRAIRFN---VRPMGRTATGVRGLRLAD-
-DVVGMISIDSEATILVVSEKGYGKRTDLEDYRVTNRGGKGVKTIKVTD-KTGELVAIKDVT-KDDLMIINKSGIVIRIAMSHLRVMGRATQGVRLINLK
-NEIASVAKVE-
>tr|R9GXI4|R9GXI4_9SPHI DNA gyrase subunit A OS=Arcticibacter svalbardensis MN12-7 GN=gyrA PE=3 SV=1
MEDFIDDEEVVITISHEGYIKRTPLTDYRTQGRGGKGSIGSNS-DQDFIEQIIIASNHNYMLFFTEAGRCFWLRVYEIPEGSRTSKGRAIQNIINIPKEE
NIKAYIKVKK--ENNFIIMCTAKGTIKKTSLMAYSR-RSNGINAININEGDQLLEANLTDGKSEIVMALRSGRAIRFN---VRPMGRTATGVRGVTLAD-
-DVIGMLSINNEATVLVVSEKGYGKRTNLEDYRVTNRGGKGVKTLNVTD-KTGDLIAIKDVT-TDDLMIINKSGIVIRIAISALRVMGRATQGVRLISLK
-DAIASIAKVE-
>tr|U1MQH3|U1MQH3_9MICO DNA gyrase subunit A OS=Agrococcus pavilionensis RW1 GN=gyrA PE=3 SV=1
MEDLIPEEQVVMSLTTGGYIKRTRIDQYRAQHRGGKGVRGA-QRSDDIVEHFGVTSTHDWLLFFTNFGRVYRMKAYEIAEAGRDAKGQHVANLLAFQPDE
RVQTVLQLR---AD-YLVLATQQGQVKKTRLELFDT-RSGGIIAINLAE-DRVISAM--NSDDEILVISKQGRAARFAE--LRPMGRATGGVRGIRLK--
-GALAAMVIGDDGYVFVVTEQGFGKKTPVADYPSKGRGTQGVLTFSGD-H-RGALVGATIVHG-DELLLIRSSGKVIRSSVDEVRA-GRTTMGVQFAEKS
-TLVISIARNV-
>tr|A0A081NH39|A0A081NH39_9GAMM DNA gyrase subunit A OS=Endozoicomonas numazuensis GN=gyrA PE=3 SV=1
VEDLITEEDMVVTLSHGGYAKTTTLDTYQAQRRGGRGSAAS-VKDEDYVEHMLVANTHTQILCFSSKGKVYWLKVYQIPPAGRTSRGRPIVNILPLE-GE
RITAMLPVEEYTEGHFVFMATVAGTVKKTPLEQFSRPRSSGLIALGLDEGDSLVGAQITTGEKQVMLLSNSGKAIRFEETDVRAMGRTARGVRGMKLQEQ
R-VISLIIPE-ETQILTVSQNGFGKRTGVEDFRITGRGGQGVISMQCTD-RNGELIGSIQVRDGEEIMLISDQGTLVRTRVDEISVMSRNTQGVTLIKVQ
EGKLVGVARVE-
>tr|A0A081KBT9|A0A081KBT9_9GAMM DNA gyrase subunit A OS=Endozoicomonas elysicola GN=gyrA PE=3 SV=1
VEDLIDVEDMVVTLSHGGYAKTTSLDTYQAQRRGGRGSAAS-VKEEDYVEHMLVANTHTQILCFSSKGKVYWLKVYQIPQAGRTSRGRPIVNILPLE-GE
KITAMLPVEEYTEGYFVFMATMNGTVKKTPLEQFARPRSSGLIALGLDEGDTLVGAEITTGEKQVMLLSNGGKAVRFEETGVRAMGRTARGVRGMKLPEQ
R-IISLIIPE-DTQILTASAKGFGKRTSVDEFRLTSRGGQGVISMQCTE-RNGEIVGAIQVKSGEQIMLISDQGTLVRTGVDGVSSLGRNTQGVTLIRVS
EGKLVGVARVE-
>tr|Q2SCF1|Q2SCF1_HAHCH DNA gyrase subunit A OS=Hahella chejuensis (strain KCTC 2396) GN=gyrA PE=3 SV=1
IADLIAEEDMVVTLSHKGYAKTQPLEAYQAQKRGGKGAATA-IRDEDFVEKLLIANSHDTILCFTSHGKLYWLKTYEIPQASRISRGRPIVNILPLA-NE
RITTMLPVREYTADHYVFMATRQGTVKKTPLENFSRPRSSGLIALALDEGDMLIGAAITDGKKDVMLFSSSGKAIRFNEDDVRPMGRTARGVRGIRLAQQ
T-VVSLIIPQ-DAYILTASRKGYGKRTAVSEFPVYGRGGQGVIAIQCSE-RNGDLVSAVQVISGDQLMLISNQGTLVRTRSDEVSIVGRNTQGVRLIRLS
ESDLVGVERIA-
>tr|A0A0A3AKB0|A0A0A3AKB0_9PAST DNA gyrase subunit A OS=Chelonobacter oris GN=gyrA PE=3 SV=1
LEDLIAPEDVVVTLSHEGYVKYQPLSDYEAQRRGGKGSAT-KMKEEDFIERLLVANTHDTILCFSSRGRLYWLRVFQLPQASRGARGRPIVNILPLQ-DE
RITAIL--P--AENKYIFMATASGTVKKTALTEFSR-RASGLIAINLRDNDELIGVDITEGNNEIMLFSSQGRVVRFSEEAVRAMGRTATGVRGIRLATD
SIVVSLVVPKNDGAILTATQNGYGKRTLLGEYPAKSRNTKGVISI--SE-RNGKVVAAVQVA-NDQIMLITDAGTLVRTRVSEVSTIGRNTQGVRLIRTA
-NHVVGLEKVC-
>tr|A0A0A2Y252|A0A0A2Y252_9PAST DNA gyrase subunit A OS=Gallibacterium genomosp. 1 GN=gyrA PE=3 SV=1
LEDLINPEDVVVTLSHEGYVKYQPLSDYEAQRRGGKGSAT-KMKDEDFIEKLLVANTHDTILCFSSRGRLYWLKVYQLPQASRGARGRPIVNLLPLQ-NE
RITAIL--P--AEDKFIVMATAGGLVKKTTLTEFSR-RTSGIIAVNLRDDDELIGADITEGNNEIMLFSAQGRVVRFDENAVRAMGRTAAGVRGIKLATD
SIVVSLVIPKTNGAILTATQNGYGKRTALAEYPTKSRNTKGVISI--SE-RNGKVVAATQVE-NDQIMLITDAGTLVRTRVAEISLVGRNTQGVRLIRTS
-TQVVSIERIC-
>tr|A0A0K6GVK4|A0A0K6GVK4_9GAMM DNA gyrase subunit A OS=Idiomarina woesei GN=gyrA PE=3 SV=1
MEDLINEEDVVVTLSHHGYVKYQPLTEYEAQRRGGKGSAT-KMKDEDFIERLWVANTHDTILCFSTRGRIYWMKVYQLPLATRTSRGRPIVNLLPLE-DE
RITAIL--P--PDDKYIVMATRNGTVKKTPMEAYSR-RSGGIIALNLNDGDELIGVDVTTAGDEVMLFSDAGKVVRFSEEQIRSMGRTATGVRGIRLE--
-GVVSLIVPRTVPTILTVTENGYGKRTPITDYPAKSRATKGVVSI--SE-RNGLVVGAMEVV-ANQIMLISNKGTLVRTRVNEVSVVGRNTQGVRLIRTG
-DKVVGMQRID-
>tr|W7QIX3|W7QIX3_9ALTE DNA gyrase subunit A OS=Catenovulum agarivorans DS-2 GN=gyrA PE=3 SV=1
MEDLIAEENVVVTLSHEGYCKYQPLTEYEAQRRGGKGAAT-KMKDEDFIEKLLIANTHDTILCFSDRGRLYWLKVYQLPLATRTARGKPIVNLLPLE-GE
RISAIL--P--EEDKFIIMATANGTVKKTRLTEYSR-RANGIIALNLNEGDHVIGVDITHGDSDILLFSDAGKVVRFNEQQVRPMGRTATGVRGIKLD--
-TVVSMIVPHGDGAVLTVTENGYGKRTPLEEYPAKSRATLGVVSI--SE-RNGSVVGAVQVN-GDEIMMITNKGTLVRTRVGEVSVIGRNTQGVRLIRTA
-GLVVGLQRIE-
>tr|A3WL75|A3WL75_9GAMM DNA gyrase subunit A OS=Idiomarina baltica OS145 GN=gyrA PE=3 SV=1
MEDLINEEDVVVTLSHEGYVKYQPLTEYEAQRRGGKGAAT-KMKDDDFVERLWVANTHDTILCFSTRGRIYWMKVYQLPLASRASRGKPIVNLLPLE-DE
RITAIL--P--PEDKFVIMATKHGTVKKTPLPEYSR-RNGGIIALNLNEGDELIGVDITDGEQEIMLFSDGGKVVRFREDQVRSMGRTATGVRGIRLE--
-GVVSLIVPGTQAAILTVTENGFGKRTLVEEYPTKSRATKGVVSI--SE-RNGAVVGAMEVV-GNEIMLISNKGTLVRTRVNEVSMVGRNTQGVRLIRTG
-DQVVGLQRID-
>tr|K2KWR0|K2KWR0_9GAMM DNA gyrase subunit A OS=Idiomarina xiamenensis 10-D-4 GN=gyrA PE=3 SV=1
MEDLINEEDVVLTLSHHGYVKYQPLTEYEAQRRGGKGSAT-KMKDEDFIERLWVANTHDTILCFSTLGRIYWMKVYQLPLATRISRGRPIVNLLPLE-NE
RITAIL--P--PEDKFVVMATRNGTVKKTPLVDYSR-RNGGIIALNLVDDDELIGVDITDGGDEIMLFSDGGKVVRFTEDQVRSMGRTATGVRGIRLE--
-GVVSLIVPRAEPKILTVTANGFGKRTGITQYPAKSRATKGVVSI--SD-RNGPVVGAMEVI-GNEIMLISNKGTLVRTRVNEVSTVGRNTQGVRLIRTA
-DTVVGLQRID-
>tr|A0A0A1GQN9|A0A0A1GQN9_BIFLN DNA gyrase subunit A OS=Bifidobacterium longum GN=gyrA PE=3 SV=1
VEDLIAEENVVVTVTHSGFIKRTKADEYRSQHRGGKGIKGT-KREDDVVDHFFLTSTHNWLLFFTNKGRVYRIKAYELPEGSRDSKGQHVANLLQFAPDE
SIQTVLSIP---AK-YLVLATRSGKVKKTPLAEYDS-RQGGLIAVRLMAADELIGAA--NAEDDIILVSKLGMSLKFQE--LRPMGRQTAGVQGMKFR--
-DLLAMDVVPG-KDLFVVTNEGFAKRTAISEYRLQGRNGLGIKAVQLV-E-RGALVGALVVSD-DQVMAIMKSGKVIRSNVDEVKR-GRNTQGVTFAKPD
-GTILSIARNE-
>tr|A0A0F9WIZ7|A0A0F9WIZ7_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_0350510 PE=3 SV=1
LADLITEEERVVTISHGGYAKSQPLADYQAQRRGGRGAATG-VKDEDYVSHLLVAHSHTTLLLFSSRGKVYWLKTYEIPEASRTARGRPLVNLLPLE-GE
FISTMLPVDEYTEGWFIFMATANGTVKKTPLVQFSRQRSVGLIALDLDEGDTLISAALTNGEREIMLFSDGGKVTRFKETDVRAMGRTARGVRGMRLPAQ
H-LVSMLIAEAGTQILTASSRGFGKRTAVEDFPQYKRGGQGVIAMVSNE-RNGPLVGAVQVVDGEEIMLISDQGTLVRTRVNEVSCLSRNTQGVMLIRLA
SDKLVGLERVQ-
>tr|K4KUY1|K4KUY1_SIMAS DNA gyrase subunit A OS=Simiduia agarivorans (strain DSM 21679 / JCM 13881 / BCRC 17597 / SA1) GN=gyrA PE=3 SV=1
IEDLITEEDRVVTISHGGYAKSQPLTDYQAQRRGGQGSATA-VKDEDFVEHLLIANTHTTILLFTNAGKVYWLKVYEIPLAGRQSRGRPVVNLLPLA-GE
RVTSILPVDEYDDDHFIFMATANGTVKKTALTQFSRPRSVGLKAIELDEGDQLVETAITDGKQTIILFASTGKAARFAEDDVRSMGRVSRGVRGIRMP--
EGVVGMVVPQENGYVLTVSENGYGKRTQVDEFPTKGRGSQGVIAMASSE-RNGALVGAVQVMDGEEIMLISDLGTLVRTRVDEVSVLSRNTQGVRLIKVK
DGQLVGVERIA-
>tr|A0A078M8V7|A0A078M8V7_9PSED DNA gyrase subunit A OS=Pseudomonas sp. 12M76_air GN=gyrA PE=3 SV=1
VADLITEEDRVVTISHGGYAKSQPLSDYNAQRRGGRGAATG-VKDEDYVSHLLVANSHTTLMLFSSKGKVYWLKTYEIPEASRTARGRPLVNLLPLD-GE
YITTMLPVEEYTEGWFIFMATANGTVKKTPLPQFSRQRSVGLIALDLDEGDTLISAALTDGNKQIMLFSDGGKVTRFNETDVRAMGRTARGVRGMRLPEQ
R-LVSMLIAEDGTEILTASQHGYGKRTPVEDFPQYKRGGQGVIAMVTND-RNGPLVGAVQVVEGEEIMLISDQGTLVRTRVSEVSSLSRNTQGVTLIKLG
NGKLVGLERVQ-
>tr|I3ID33|I3ID33_9GAMM DNA gyrase subunit A OS=Cellvibrio sp. BR GN=gyrA PE=3 SV=1
TEDLINVEDRVVTISHGGYAKSQPLDDYQAQRRGGMGSATA-VKDEDYVQHLLIASTHDTVLLFTNAGKVYWLKVYMIPVAGRQSRGRPVINLLPSLEGE
HITSILPVKSYDDDKFIFMTTANGTVKKTALTQFSRQRSVGLRAIELDEGDTLVGTAITNGSCDVILFSSSGKAARFRESQVRAMGRTSRGVRGIRLAEQ
R-VVGMVIPM-NGQVLTVSENGYGKRTEVGEFPAKGRGSQGVIGMQTTE-RNGQLVGAVQVFDGEEIMLISDQGTMVRTRVDEVSVLSRNTQGVRLIKLK
EGRMQGLERIE-
>tr|A0A0Q9E4J9|A0A0Q9E4J9_9FLAO DNA gyrase subunit A OS=Flavobacterium sp. Root935 GN=ASE40_18080 PE=4 SV=1
IEDLIADENVVITISHAGYIKRTNLTEYKTQNRGGVGQKSAGT-DQDFLEHMFVATNHQYMMFFTQKGKCFWMRVYEIPEGSKTAKGRAIQNLVNIESDD
KVKAFICTQK--NTHNLVMVTKQGQVKKTSLEKYSK-RVNGVAAITIKEGDELLGAQLTDGESQIILAVKSGKLVRFE---TRPMGRTASGVRGITLKE-
-DVIGMVTVGKDSQILVVTENGYGKRTKLVVYRITNRGGKGVKTLNITE-KTGKLISISAVT-ADDLMIINKSGLTIRMAIEDLRVMGRATQGVRLINLK
-KSIAAVTKVM-
>tr|D4ZUF9|D4ZUF9_ARTPN DNA gyrase subunit A OS=Arthrospira platensis (strain NIES-39 / IAM M-135) GN=gyrA PE=3 SV=1
DTDLIANEKAIILLTEQGYIKRMPVNTFEAQNRATRGKSGTKM-EDDGVKHFLSCRDHDSILFFTERGVAYCLKAYQIPIGSRIARGVPIVQMLPIPRDE
KITSLVAVG---NDEYLVMLTKGGYIKKTALSAFSNIRSNGLIAISLNEGDELRWVRSARVDDSIIIGSRLGMAIHFHT--LRPLGRATRGVKSMKLK--
-DLIGMDILPSGVSILVITTRGYGKRVPVSQFRLQNRAGKGIIATKFHLS-GDCVVALQVVH-TDELMLITSRGIIIRQVISAISRQSRNATGVRVQRLD
-EAIAAVALVP-
>tr|U7QQT2|U7QQT2_9CYAN DNA gyrase subunit A OS=Lyngbya aestuarii BL J GN=gyrA PE=3 SV=1
DTDLIANEKAIILVTEQGYIKRMPVNTFDAQNRATRGKSGTKM-EDDGIDHFLSCCDHDSILFFSDRGVVYCLKAYQIPVASRTARGVPIVQMLPIPKQE
RITSVVPVS---DDDYLVMLTKGGYIKKTELSAFSNIRANGLIAISLGEGDELRWVRLAKADDSIIIGSRLGMAIHFRT--LRPLGRATRGVKSMKLG--
-DLISMDILPSELAIMVITAGGYGKRVPVSQFRLQNRAGKGIIATKFHLT-TDEVVGLQVVN-DNELMLITSRGIIIRQAVNAIPTQSRSATGVRVQRLD
-EAIAAVAIVP-
>tr|F7XY92|F7XY92_MOREP DNA gyrase subunit A OS=Moranella endobia (strain PCIT) GN=gyrA PE=3 SV=1
IEDLISQEDMVVTLSHHGYVKSQPITEYKAQRRGGKGSAAS-IKKGDFIDRLLIANTHETILLFSNRGRMYWLKVYQLPEARRSARGRPIVNLLPLE-NE
RITAILPVREYQYGYHIFMATANGTVKKTSVINFRRQRSTGITAINLNHGDELIGVDLTNGNDDVMLFSTHGKVVRFPETQVRSMGRTATGVLGINLA--
EDVVSLIVPRS-GTILTVTQHGYGKRTVPAEYPTKSRATQGVISIKVSK-RNGEVVGAVQVEDYDQIMMITNTGNLVRMRVSEVKIVGRNTNGVTLIRTA
QNNVVGLQRIA-
>tr|U1SM47|U1SM47_9BIFI DNA gyrase subunit A OS=Alloscardovia omnicolens F0580 GN=gyrA PE=3 SV=1
VEDLIAEENVVVTVTHSGYIKRTKADEYRSQHRGGKGIKGA-RREDDVVDHFFSTSTHNWLLFFTNEGRVYRLKGYELPEGSRDSKGQHVANLLQLGPQE
KIQQILSIK---AE-YLVLATKSGKVKKTKLPEYDS-RQGGLIAVRLMDSDELIGAA--NSNDDIIVVSHAGMSVKFAD--LRPMGRQTAGVQAMKFK--
-DLLSMAVVPA-SDLLVVTSEGFAKRTALSEYRLQGRNGYGVKAINLV-E-RGLLVGAVVVED-DQIMAIMKSGKVIRSDVSEIKR-GRTTQGVTLAKPD
-NEIVSIARNA-
>tr|R7G0V5|R7G0V5_9PROT DNA gyrase subunit A OS=Acidiphilium sp. CAG:727 GN=gyrA PE=3 SV=1
EADLIEREDVVISMTHLGYVKRLSVKECKAQRRGGKGVTAHKP-DEDFVENMFVCSTHDDLLFFSSLGKVYRLKGYEVPEQ-KAARGRAIVNLIQVDNGE
RITAIIPRK-R-AEGYVMMATKFGLIKKTPISQFDSIRKGGKIAISLLPGDELISVQFTNGEDEILVGSNYGKCIRFS---VRATGRDTQGVRSMDLD--
-YVIDMQVVH-GDTVITVSSLGYGKRSSLDDYRLQSRAGKGIKAGIFNE-TTGNLVGIKPVR-E-DVMMISDSGIAIRVLVDEISL-GRATRGVKVMRLD
--KIATVTIAP-
>tr|R7K6A9|R7K6A9_9FIRM DNA topoisomerase (ATP-hydrolyzing) OS=Subdoligranulum sp. CAG:314 GN=BN603_01289 PE=4 SV=1
IGDLIEKEDVVVSMTHFGYVKRLPVNEYHAQKRGGKGVTAHKP-EEDFVENMFITNTHDDLLFFTNFGKVYSIKGYEVPEQ-KTARGRAIVNLLQLGDGE
KVTTVIPRK---ARGYLFMATKRGLVKKTDIQEFDSIRKVGKIAISLNEGDELVGVALTRGYDEILIASSTGKCIRFA---VRAMGREAQGVRSMKID--
-AVVDMTVV--GCEVITVSENGYGKRSDITDYRLQSRAGKGIKAGTFNA-KTGRLVNLKLVE-DDDIMVIADNGVVIRMRARDVSK-GRDTQGVRIMKFK
-DSKVCVANTP-
>tr|R5W4W4|R5W4W4_9DELT DNA gyrase subunit A OS=Corallococcus sp. CAG:1435 GN=gyrA PE=3 SV=1
IGDLIEKEDVVISMTHLGYIKRLPVSEYHTQKRGGKGVTAHKP-EEDFVENMFITNTHDDLLFFSNKGKVYCIKGYEVPE-ERTARGRAIVNLLQLDNGE
KVTAVIPRK-N-SEGNLFMATKNGLVKKTNLEEFQSIRKTGKIAISLLDGDELIGVDMTSGSDEILMASHEGKCIRFK---VRPMGREAQGVRSMKLD--
-YVVDMAVV--GLEVLTVSENGFGKRSDIEDYRLQSRAGKGIKAGVFNA-KTGKLVNLKLIN-ENDVMLIANNGVVIRVRANDISK-GRDTLGVRIMKFK
-EQVVCVSESP-
>tr|R6GK36|R6GK36_9FIRM DNA gyrase subunit A OS=Firmicutes bacterium CAG:552 GN=gyrA PE=3 SV=1
IADLIDKEDVVISMTHLGYVKRLPVSEYKAQHRGGTGVTGHKP-EEDFVENMFVTNTHDDVLFFSSLGKVYSIKAYEIPE-ERATRGRAIVNLLQLSDNE
KINAVIPFV-G-QSGYMVMATAKGLIKKTDVAEFASIRRSGKVAISLTDGDELISVQFSSGNDEILVAASSGKCIRFS---VRAMGRDTQGVKSMDIS--
-RVVDMIIL--NKKILTVSSGGYGKRSSEEDYRLQQRAGKGIKAGVFSE-KTGRLVNLKQVG-NDDVMVITSNGIIIRMPSSEISE-GRDTQGVRIMKMR
-DEVVCVAVVA-
>tr|R5FF58|R5FF58_9FIRM DNA gyrase subunit A OS=Faecalibacterium sp. CAG:1138 GN=gyrA PE=3 SV=1
IEDLIEKEDIVVTLTHGGYIKRMPVAEYQSQHRGGMGVTAHKT-EDDFVETMFTTSTHDDLMFFTNMGKVYRLKGYEVPE-ARMGRGRAVVNLLQLEQGE
KVTTLLPVV-DNDDCFLMLATRNGLIKKTSLTEFVNIRRTGKKAIKLLDDDELIAAIITKGDDELIMASRDGKCIRFA---VRAMGRDAQGVKSIKLN--
-YVVDMALV--GMEVLTVSAGGYGKRTSPDEYRCQGRAGKGIKAGVFNE-KTGKLVGLKMID-AHDIMMITDSGTIVRVHAEEISC-GRDTQGVRVMRIK
-AEIVSIVTTP-
>tr|R7K8Y6|R7K8Y6_9FIRM DNA gyrase subunit A OS=Acidaminococcus sp. CAG:917 GN=gyrA PE=3 SV=1
IADLIEKEDVVITMTHEGYVKRLPVAEYRSQHRGGTGITAHKA-EEDFIEEMFTCSSHDDLLFFTNLGKVFGLKAYEIPEQ-RTARGRAMVNLLQLTPGE
KVTNVLPFY-T---GYLVLATKKGLIKKTDVSEYMSIKKNGKIAITFNENDELIAAYFSSGEDEIIVGATNGNCIRFS---VRPTSRTAMGVKSIELP--
-EVVDMAVLKEGSEILTITEKGFGKRSEYPDYP-QGRAGKGVKAGVFNS-KTGRLVALKVLP-EMDVMIITNGGIIIRMVADEIS-FGRDTQGVKVMRLK
-DLISSVTLTP-
>tr|R6WSY2|R6WSY2_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:349 GN=gyrA PE=3 SV=1
IEDLIEKEDIVVSMTHGGYVKRQPVAEYKSQHRGGVGITAHKT-DEDFVESIFTTSTHDDLMFFTNFGKVYVIKGYEIPES-RNSRGRAVINILQLDPGE
KVATLLPVP-R---GYLMLATKQGLIKKTALSEFESIRKTGKKAIRLVDGDELIAAMITKGDEELIIASHEGKCIRFR---VRAMGRDCQGVRSMKLN--
-FAVDMAMVEEDKEVLTISENGFGKRSSPDEYR-QGRAGMGVKAGVFNE-ETGKLVCLKMIN-DNDIMIIADNGIIIRVAADEIR-IGRDTKGVKVMNLR
-GKIMSIAVVP-
>tr|A0A0E3N5Y2|A0A0E3N5Y2_MYCSY DNA gyrase subunit A OS=Mycoplasma synoviae ATCC 25204 GN=gyrA PE=3 SV=1
EEQLIPRKDIVITATVDGFVKRVNLEEYNLQNRGG-G--TMK--GD-AILSIIQTNTHVDLFLFSNLGKVYKLRAYKIQED-KKSKGNSFANLVELEN-E
K--RILPV---ESNLHLLTVTKKGIVKKTALDNFKK-R-NGIKAFKLK--DELKD---VD---LVLVANNHKNVV------IRSQARNSIGVQGMKLD--
-KVQSISSSK-GEFVLTIGEFGFGKLTDH-EYS-TNRNAKGKTSI---PAKAGNV-FAKFVN-TDELLIITAQGNTIRTQL-QVSV-SR---GVRIIKLN
G-KIISVEVIK-
>tr|A0A0D5ZJ66|A0A0D5ZJ66_9MOLU DNA gyrase subunit A OS=Mycoplasma meleagridis GN=gyrA PE=3 SV=1
DEDLIAEKDIVITSSTNGYVKRINLEEYNTQRRGG-G--VMK--DD-DISNIIKTNTHTDLLLFSNKGKAYSIRAHQIPES-KQSKGIPFINIIESNG-E
K--SMLDVP--DENTYLATVTKKGIMKRTPLSEYQN-R-NGLNAFKLQ--DELVR---LD---IVLIANNDKNII------VRATGRNSVGTRGMKLDN-
-QVISASS---GEFILSIGSKGFGKLTKS-EYR-THRGSKGVSGI----EKAGNV-FARFVE--DEVLIITTNGITIRINV-DIAL-SR---GVKIISLK
N-EIVA-AEVI-
>tr|F9QCW5|F9QCW5_9MOLU DNA gyrase subunit A OS=Mycoplasma anatis 1340 GN=gyrA PE=3 SV=1
NESLIPESDIVITLSVKGYVKRLNLEEYREQKRGG-G--YAK--DD-DISLILQTKTHTDLLLFSNFGKVYKKRGHEIQEN-KQSKGIPFINLIPTNG-E
K--SILPV---EENKFLTTITKNGIIKKTDLTLFSN-N-SGLNAFKLK--DELLT---VS---TILVANNTNNAI------VRAMGRNAVGVKAMNLD--
-N-VSASSEK-GDYILSIGSEGYGKLTHK-DFR-IKRGGKGVTAI---GEKAGNI-FAKFVS-EDQALIITKLGLTIRLNL-NVSV-SR---GVKIIDIK
N-EIVSVEIIK-
>tr|A0A0F6X1T1|A0A0F6X1T1_9MOLU DNA gyrase subunit A OS=Mycoplasma canis GN=gyrA PE=3 SV=1
DEDLIPQSEIVITSSVNGYVKRINLDEYNTQNRGG-G--IMK--DD-DISMIIKASTHTDLLLFSNFGKAYALRGYQIPES-KQSKGVPFINIIETEG-E
K--SIIDAG--EDDLYLATITKKGIFKKTPLSLFSN-R-NGLLAFKLQ--DKLVR---AD---NILVANNYKNIA------VRALGRTAMGVKAIKLVD-
-QVINASS---GNLVLSLGSKGFGKITDE-EYR-ARRGAKGISGI----EKAGNV-FASYVK--DELLVITKSGSTIRVKI-QISE-SR---GVKIINLK
S-EIVA-VEVI-
>tr|R5FP64|R5FP64_9BACT DNA gyrase subunit A OS=Prevotella sp. CAG:924 GN=gyrA PE=3 SV=1
AEDFYPNDPVVITVSHLGYIKRTPLANFREQSRGGVGSKGAHT-DNDFIEYIYPSTMHQTMLFFTKKGRCYWLKCYDIPEGDKTSKGRAIQNLLDIEPGD
AVNAFLRLRD--NSHYVVFATKSGIVKKTCLKQYSN-RSKGVIAINILEGDEVVDVRLTNGKNELILADRNGRAVRFD---VRAMGRNSTGVTGMRID--
-DVVGMIVVNNTETVMVVSENGYGKRSMVE-YRKTNRGTRGVKTLNITE-KTGRLVAIKNVT-ENDLMIINKSGITLRLPVQEIRVIGRTAQGVHLINLT
KNSIASVCKVM-
>tr|D1PUI7|D1PUI7_9BACT DNA gyrase subunit A OS=Prevotella bergensis DSM 17361 GN=gyrA PE=3 SV=1
AEDFYPNDPVVITVSHLGYIKRTPLSDFREQARGGVGSKGAHT-DKDFTEYIYPATMHQTMMFFTKKGRCYWLHCYDIPEGDKTSKGRAIQNLLNIDPDD
SVNAFLRLRE--NSHYVVFATKNGTVKKTNLKEYSR-RANGVIAINIVEGDEVVDVRLTNGNNELILANRNGRAVRFD---IRSMGRVSTGVRGMRID--
-DVVGMIVVNNTETVMVVSEEGYGKRSDVA-YRKTNRGGKGVKTMSITE-KTGRLVAIKNVT-ENDLMIINKSGIVIRLAVAEVRVMGRATQGVRLINLA
KNTIASVCKVM-
>tr|F8NCM9|F8NCM9_9BACT DNA gyrase subunit A OS=Prevotella multisaccharivorax DSM 17128 GN=gyrA PE=3 SV=1
AEDFYPNDPVVITVSHLGYIKRTPLKEFREQARGGVGSKGAHT-EKDFTEFIYPATMHQTMLIFTRLGRCYWLHCYDIPEGDKASKGRAIQNLLNLESGD
TVNAFLRLRG--NSHYVVFATKNGTVKKTCLKEYSR-RANGVKALIIADGDEVVDVRLTNGSNELILADRNGRAVYFD---VRPSGRAAMGVRGMVLD--
-DVVGMIVVNNKETAMVVSENGYGKRSEIV-YRKTSRAKKGVKTIAITE-KTGKLVAIKNVT-ENDLMIINKSGIVIRMAVADVRVMGRATQGVRLINLT
KNCIASVCKVM-
>tr|E7GCS7|E7GCS7_9FIRM DNA topoisomerase 4 subunit A OS=Coprobacillus sp. 29_1 GN=parC PE=3 SV=1
EEAMILPEDIYVSITQDGYIKRISQRSYKASE--N---------DD-VLVDL-HFNTLDKLLVFTDKGNYMYIPLHKLEE-----LGKHISYLIKV-SEE
K--GSVLVK--YP-LYIILASRFGQMKRVELKEFD----KPMKCINLK-D-SLLQ---D--QQGIVLTTQAGYAT------I--LGVKAGGIKGINLK--
-EIAMNIFNPLTDSFILISDQPGIKRLRIS------RATKGNLIF----KPHIQL-YAFVLE--QLNIET-DS-QKIDIFV-DYTH---ESKPSILTAIK
---IRYVYNPK-
>tr|R6XRM3|R6XRM3_9FIRM DNA topoisomerase (ATP-hydrolyzing) OS=Firmicutes bacterium CAG:313 GN=BN602_00049 PE=4 SV=1
-EEFIAKEDVILMITHDGYLKRLSKKAFFGTNE------K----GD-VITDLYAVATTDTLIQFTDRGNYIFLPIHKIPEK-HKDQGIHISTLI-GEN-E
K--FSFPVT---EEKYVLLATKSGLIKRIQLSSLYV-RYKALKATKLK-D-AVVS---K--EVV--IATKDGFMN------VSVIEPASFGVKSIELKR-
-PVVGAKYVS--DIVLILTNRGNIKRMRP-EIN-GKKNNVGKMYL--VS--NMHA-DLE---------VIHAKNANSDL---SYVF-EK---EIDYTVLR
A---------A-
>tr|R7GL35|R7GL35_9FIRM DNA topoisomerase 4 subunit A OS=Catenibacterium sp. CAG:290 GN=parC PE=3 SV=1
QQAMIISEDVYVSITRDGYFKKISTRSYKASD--E---------TD-MLVDL-FENTLDVILSFTNKGNYCFVPVYKLED-----LGKHLSYLIKL-GDE
K--GNILVK--LD-QYVVLSSKNGQIKRVSIKDFN----KPLKCMNLK-D-ELVS---D--TKGIITVTKAGYGT------I--LGVKAGGVKGINMR--
-EAFMCVFDPSVSSLLLILNPAHFKRIHIS------RATKGTLLF----KLPTKF-TGFISN--EFIVKS-GT-ETMKIVS-DISF---SAKANTLKQC-
---FDFIDDVH-
>tr|B1C1X9|B1C1X9_9FIRM DNA topoisomerase 4 subunit A OS=[Clostridium] spiroforme DSM 1552 GN=parC PE=3 SV=1
EKAMILSEDVNISITRDGYIKRISNRSIKASE--K---------ND-YLVSM-YKNTLDHLLLFSDAGNYLFIPVHKIEE-----PGKHVSYLVKM-DSE
K--ASILVK--LP-LYVMIATKNGQIKRTLLKDFE----KPLKCIGLK-D-KVVD---N--DQGIILTTKKGYGA------V--VGIKALGIKAINLK--
-EVSLDTFDPMDHSLVLISDSGGIKRIKIS------RATKGVMLF----KLTTYK-KALIVD--QIMITL-NNQTVVEFKV-DYHN---EQKFSSLVKLN
D--IDDIYIDK-
>tr|A0A0R2HDK9|A0A0R2HDK9_9FIRM Topoisomerase iv, subunit a OS=Kandleria vitulina DSM 20405 GN=IV49_GL001211 PE=4 SV=1
AQAMIVSEDCYVSVTRDGYIKKISLRSYKASQ--N---------DD-RLVSL-CQNTLHTLLVFTNRGNYCFVPIHKLEE-----LGKHISYLIKL-NDE
K--ATVLVK--SP-QYVMMASRDGAIKKVAIADFE----RPMKCMNLK-D-EMVS---S--HDGVILASKAGYAA------I--VGIKAGGVKGIRLT--
-SAFMRVFNPAPQSLVIFTNPVGIKRIHVS------RANKGNLIF----KPQITY-DGYIMD--TLTLYG-ES-GSIEVCA-DFNF---INRPGGIKAFE
---IDFIYDSR-
>tr|A0A0J9BRE5|A0A0J9BRE5_9FIRM DNA topoisomerase 4 subunit A OS=Coprobacillus sp. 8_1_38FAA GN=parC PE=3 SV=1
EKAMIISEDIYVSITRDGYIKRISQRSINAST--N---------DD-ILISL-YKNTLNHLLLFTNKGNYLFVPVHKIEE-----LGKHVSYLVKV-NDE
K--STILVK--LP-LYVLLATKNGQIKRTLLKDFE----KSIMCMKVK-D-EIVS---D--HQGIFIATRAGYGG------V--IGLKAAGIKALNLK--
-TQSVETFNPMTYSIMLFSEDGQMKRLKLS------RTTKGITLY----KLTIYH-SALIMT--EAKVYT-DQ-ETYDLKA-DFNY---ESRFSSFIKLK
D--IQCVLKDH-
>tr|R5QWA6|R5QWA6_9FIRM DNA topoisomerase 4 subunit A OS=Coprobacillus sp. CAG:235 GN=parC PE=3 SV=1
EKAMIISEDIYVSVTRDGYIKRISQRSMKAST--N---------DD-ILISL-HHNTLNHVLLFTNKGNYLFVPVHKIEE-----LGKHVSYLVKV-GDE
K--SSILVQ--LP-LYVLMATKNGQIKRTLLKDFE----KAITCMKVK-D-TMIC---D--QQGIFIVSKAGYGG------V--VGLKAAGIKALNLK--
-SAAVDVFDPLNYSVLILSEDGQMKRLKLN------RTTKGTTLY----KLTIYK-NAFVLS--SASVYT-SKSKEYTFKP-DFNN---ESRFSSFIKLE
D--ILWSQINR-
>tr|M2PN74|M2PN74_9FIRM DNA topoisomerase 4 subunit A OS=Eggerthia catenaformis OT 569 = DSM 20559 GN=parC PE=3 SV=1
EQAMIIAEDCYVTVTRDGYIKKVSERSYKASE--D---------DD-YMVSL-HKVTLNTLLVFTDAGNYCFIPVYKLEE-----LGKHISYLVKM-GDE
K--STVLIK--VP-YYIIIATKDGQIKRVLLKDFE----KAYKCINLK-D-RVVD---K--HNGLVLGTKAGYAT------V--MGLKASGVKAMNIK--
-EAYMCCFDPSDESLLLFTKPAGIKRIHVG------RGARGIIVC----KPEQII-KGIVAH--QLTLYS-NQ-EPLNLYA-DYSF---ANRVSTIKGLN
---IDYIYYAN-
>tr|B0N7F5|B0N7F5_9FIRM DNA topoisomerase 4 subunit A OS=Erysipelatoclostridium ramosum DSM 1402 GN=parC PE=3 SV=1
EKAMILSEDINVSITRDGYIKRISNRSIKASE--G---------ND-YLVSM-YQNTLDHLLLFTDAGNYLFIPVHKIEE-----AGKHVSYLVKL-NGE
K--GTILVK--LP-LYVMLATKNGQIKRTNLKDFE----KPLKCMGLK-D-RVVD---D--NQGIILTTKAGYGA------V--VGIKAAGIRAVNLK--
-EVSLNIFNPLSSSLIVISEEGGVKRIKIG------RATKGTLLY----KPIIYK-DSVIVD--LITVTL-NDQTSFEFKA-DYNN---EQKPSVANKLT
N--IDDVYINS-
>tr|K9ZE38|K9ZE38_ANACC DNA gyrase subunit A OS=Anabaena cylindrica (strain ATCC 27899 / PCC 7122) GN=gyrA PE=3 SV=1
DLDLIANEKVLILITKQGYIKRMPVSTFEAQSRATRGKAGAKV-EDDTIEHFFTCCDHDSVLFFSDRGVVYSMRTYQIPLGSRTSRGTPIVQMLPIPKEE
KITSIVPVD---DDEYLVMLTKGGNIKKTSLAAFSHIRANGLIAISLEEGDQLRWVRRAKVEDSVIIGSRNGMAIHFRC--LRPLGRATRGVKSMKLK--
-DLVGMDILPAGPWVLVITMGGYGKRVPVGQFRLQNRAGQGLMATKFRKT-KDKLATLHIVN-DEEIMMVTNRGIIIRQAVNAISVQSRSATGVRVQRLD
-DAITGVAIVP-
>tr|A0A0J1HIG0|A0A0J1HIG0_9GAMM DNA gyrase subunit A OS=Photobacterium ganghwense GN=gyrA PE=3 SV=1
LEDLITQEDVVVTLSHEGYVKYQVLSDYEAQRRGGKGAAT-RMKDEDFIERLLVANTHDTILCFSSRGRMYWLKVYQLPQASRTARGKPIVNILPLE-GE
RITAIL--P--EENKFIFMATADGTVKKTPLTDFSR-RSAGIIAVNLRDGDSLIGVDITAGGDDIMLFSKAGKVVRFSE-QVRGMGRTAAGVRGIKLA--
-NVVSLIVPHNDGDVLTVTENGFGKRTELLEYPAKSRATQGVVSI--TE-RNGSVVGAIQVL-GDEFMMITNGGTLVRTRVAEVSRVGRNTQGVTLIRTS
-DQVVGLQRIE-
>tr|I4VP45|I4VP45_9GAMM DNA gyrase subunit A OS=Rhodanobacter fulvus Jip2 GN=gyrA PE=3 SV=1
VLDLIAPEDMVVTLSHTGYVKRQPASTYRSQRRGGKGSASA-LKEEDVVEQLWVVNTHDTLLTFTSTGRVYWLNVYQIPEASPGARGKPIVNLLPLG-GE
HVQAVLPIRDYSDDRYVFFATRQGTVKKTPLGEFAFQLQKGKLAIRLNEDDALVNVELTDGNSDILLFASNGKVNRFDENTVRSMGRTAAGVRGMKLAK-
-AVVSLIVA-AEGDILTATERGYGKRTPLVEFTKKGRGTQGVIGIQCSE-RNGALVAAAQVTEEHELMLISDQGTLVRTRVAEVSQLGRNTQGVTLIRLP
ADKLVSVMRLD-
>tr|T1CNT2|T1CNT2_9ZZZZ DNA gyrase, A subunit (Fragment) OS=mine drainage metagenome GN=B1B_05158 PE=3 SV=1
MLDLIAPEDVVVTLSHAGYVKRQPLTIYREQRRGGKGSATA-MKEEDFIEQLWVVNTHDTLLVFTGAGRVFWLTVYQIPDAGPGARGKPIVNLLPLE-GE
KVQAVLPVHAFDSGQYVFFATCRGTVKKTPLSEFAYRLQRGKIAINLDEGDALVDVCLTDGQRDIMLFASNGKAVRFDEDTVRSMGRTATGVRGMRLAE-
-EVVSLIV-AADGDILAATARGYGKRTALDEFPRKGRGTQGVIAIQCSE-RNGALVAVV-----------------------------------------
------------
>tr|A0A0K8QNZ4|A0A0K8QNZ4_9GAMM DNA gyrase subunit A OS=Mizugakiibacter sediminis GN=gyrA PE=3 SV=1
VLDLIAPEDMVVTLSHAGYCKRQPVNLYRAQRRGGKGSATA-MKEEDFVEQLWVVNTHDTLLTFTSAGRVFWLRVYQIPEAGPGARGKPIVNLLPLE-GE
KVQAVLPVREFDDQHYVLFATRNGTVKKTPLTEYAYRLQRGKIAINLDDGDALVDVQLTDGHRDVMLFASNGKAVRFAEDEVRPMGRTATGVRGMKLAE-
-EVVSLVVTEGDGDILTATARGYGKRTPLAEYPRKGRGTQGVIAIQCSE-RNGALVAAVQVDGAHELMLISNLGTLVRTRVAEVSQLGRNTQGVTLIRLP
AESLVGAVRVE-
>tr|A0A075K227|A0A075K227_9GAMM DNA gyrase subunit A OS=Dyella japonica A8 GN=gyrA PE=3 SV=1
VLDLIAPEDVVVTLSHTGYVKRQPASTYRAQRRGGKGSASA-LKDEDFVEQLWVVNTHDTLLTFTSTGRVYWLNVYQMPESGPNARGKPMVNLLPLG-GE
KVQAVLPVREYAEDRFVFFATKQGTVKKTPLTEFAFQLQKGKIAINLDEGDALVNVALTDGNSDVLLFASNGKTVRFDESEVRSMGRTATGVRGMKLAD-
-AVVSLIVA-AEGDILTATERGYGKRTQLDEFPKKGRGTQGVIGIQCSE-RNGPLVAATQVTEAHEMMLISDQGTLVRTRVAEVSQLSRNTQGVTLIRLP
ADKLVSVVRLD-
>tr|A0A0Q8LFY6|A0A0Q8LFY6_9GAMM DNA gyrase subunit A OS=Rhodanobacter sp. Root179 GN=ASD82_16420 PE=4 SV=1
VLDLIAPEDVVVTLSHTGYIKRQPASTYRAQKRGGKGSASA-LKDEDFVEQLWVVNTHDTLLAFTSTGRVYWQKVYQIPESGPGARGKPIINLLPLG-GE
KVQAVLPIREYAEDRFVFFATRHGTVKKTPLSEFAFQLQKGKLAIKLHDDDALVNVELTDGNSDILLFASNGKVNRFDENTVRSMGRTASGVRGMKLVG-
-AVVSLIVA-AEGDILTATARGYGKRTELAEFTKKGRGTQGVIGIQCSE-RNGALVGAVQVTEAQELMLISDQGTLVRTRVAEVSQLGRNTQGVTLIKLP
ADTLVSVMRLD-
>tr|A0A0G9H3S3|A0A0G9H3S3_9GAMM DNA gyrase subunit A OS=Luteibacter rhizovicinus DSM 16549 GN=gyrA PE=3 SV=1
VLDLIAPEDVVVTLSHTGYIKRQPASLYRAQKRGGKGSASA-LKDEDVVQQLWVVNTHDTLLTFTSTGRVYWLKVYQMPEAGPGARGKPIVNLLPLG-GE
KVQALLPVREYDPTCFVFFATRKGTVKKTPLTEFAFQLQKGKAAINLDEGDALVDVAMTGGESDILLFASNGKSVRFDEGTVRSMGRTATGVRGMRLAD-
-AVVSLIVAAGEGDILTATARGFGKRTTLDEFPKKGRGTQGVIAIQCSD-RNGSLVAATQVTETQQLMLISDQGTLVRTRVSEVSQLSRNTQGVTLIKLP
KDTLIGVVRLE-
>tr|H8L3W9|H8L3W9_FRAAD DNA gyrase subunit A OS=Frateuria aurantia (strain ATCC 33424 / DSM 6220 / NBRC 3245 / NCIMB 13370) GN=gyrA PE=3 SV=1
VLDLIAPEDVVVTLSHAGYIKRQPASAYRAQKRGGKGSASA-LKNEDFVEQLWVVNTHDTLLTFSSTGRVYWLKVYQMPEAGSGARGKPIVNLLPLA-GE
TVQAVLPVREYSEDQFVFFATRKGTVKKTPLTEFAYQLQKGKIAINLDESDALVGVALTDGESDVLMFASNGKTVRFDEGEVRSMGRTAGGVRGMKLAD-
-AVVSMIVA-REGDILTATERGYGKRTPLDEFPKKGRGTQGVIGIQCSD-RNGPLVAAVQVTEAHELMLISNQGTLVRTRVAEVSQLSRNTQGVTLIRLP
ADALVRVVRLD-
>tr|A0A098E9B7|A0A098E9B7_9ZZZZ DNA gyrase subunit A OS=groundwater metagenome GN=gyrA PE=3 SV=1
DEDLIPNTNIVLTLTNGGYIKRATEDSYKRQNRGGKGSSGVKT-ETDFLKNLVNAHSHDYVLLFTNKGKVYSIKAYMIPEAGKQSKGKAAINLINIAEGE
KIINILP---FE-NKFLLMCTAKGIVKKTKIYSYSKIKKSGIIAIRIREGDVLISAE-IEPGNHVFLVTKKGMSINFTE--VREVGRNSIGVKGIKPK--
-DVVVGMITAKSLSLLTVTEHGYGKRTILSNYRKQRRGGIGTKDI--DR--NGNVIDAKKITAEEEILLSSSSGKVIRMRAGDVREIKRNTKGVRLMGIS
-KKITSVDVIA-
>tr|K2G877|K2G877_9BACT DNA topoisomerase (ATP-hydrolyzing) OS=uncultured bacterium (gcode 4) GN=ACD_4C00342G0007 PE=4 SV=1
PKDTIPNEDIVITLSKNSYIKRIKSSSFRTQRRWW-W---VA--ED-EVKVILSTKNHNDLLFFTNTGRVFSLPAYEIPEQ-RTAKGQPIINLL-SQD-E
E--SILDMN--MNWKHLILITKKAVVKRIDIDEVSS-R-SGLIVMKPR--DELGW---TD---NLLIVSKKWKAI------VRVMWRTAAWVRWMKIWK-
-EVVEADVVSE-KYVFTVTENWLGKITDI-WYR-QWRWWSWVKVW---TAKTGDI-WVSLLT-NWEVLLISKSGQTIRITL-TIRA-SR---WVILTKIK
K-VLISATVMK-
>tr|S6HJ06|S6HJ06_9GAMM DNA gyrase subunit A OS=Osedax symbiont Rs1 GN=gyrA PE=3 SV=1
VADLITEEDMVVTISHGGYAKSQPLTDYQAQRRGGKGSVTA-VKDEDFVEHLLIASTHDTILCFSNFGKVYWLKVFEIPVASRAARGRPIINILP-LAGE
RISTILPVNEYSEDRFVFMATASGTVKKTSLVNFARPRSSGLIAVDLLDDDALIGAAITEGDDDILLVTSAGKAARFHETDVRAMGRTARGVRGVKMKDA
K-VISLIIPKEGGKILTASENGFGKQTEVSDFPCKGRGNQGVIGQQCTD-RNGGIAGAVQVFTGDDVMLISDQGTMVRTRTSEIGVLGRNTQGVRLIRVV
EGSLVGIARIQ-
>tr|B3PII5|B3PII5_CELJU DNA gyrase subunit A OS=Cellvibrio japonicus (strain Ueda107) GN=gyrA PE=3 SV=1
TEDLIAVEDRVVTISHGGYAKSQPLADYQAQRRGGMGSATA-VKDEDFVEHLLIASTHDTILCFTSVGKVYSLKVYMIPEAGRQSRGRPVVNLLP-LEGE
RITSILPVKSYDNDHFIFMATRKGTVKKTVLTEFQSLRANGKRAIELDEGDTLVGTAVTNGACDVILFSSSGKAARFRESQVRAMGRSSRGVRGIRIAEQ
F-IVGMVIPL-GGQVLTVSENGYGKRTPVDEFPAKGRGSQGVIGMQTTD-RNGELVGAVQVFDGEEIMLISDQGTMVRTRVDEVSLLSRNTQGVRLIKLK
DGRMQGIERIE-
>tr|K9VWL8|K9VWL8_9CYAN DNA gyrase subunit A OS=Crinalium epipsammum PCC 9333 GN=gyrA PE=3 SV=1
DTDLIANEKALILLTEQGYIKRMPVNTFEAQSRATRGKAGAKM-EDDGVEHFLTCCDHDSILFFSDRGVVYCLRAYQIPGASRTSRGVPIVQLLPIPRNE
KITSIVPVS---SEEYLVMLTQGGFIKKTALSAFGNIRANGLIAISLEEGDQLRWVRRARAEESIIIASRQGMAIHFRT--LRPLGRATRGVRAMNLR--
-DLISMDIIPSGLWVLVVTMGGYGKRVPVSQFRLQNRAGKGLIATKFRKG-KDQLISLRVVN-EDELMMITSRGIIIRQSVSAIPSQSREATGVRVQRLD
-DAIAAVALVP-
>tr|K9S5I2|K9S5I2_9CYAN DNA gyrase subunit A OS=Geitlerinema sp. PCC 7407 GN=gyrA PE=3 SV=1
DIDLIANEQVLILVTEQGYIKRMPINTFEAQSRATRGKAGARM-EDDVIAHFLTCCDHDSLLFFSDRGVAYCLRSYQIPTGSRNARGVPIVQMLPIPHDE
KITSVVPVS---ADEYLVMLTKGGYIKKTALAAFSNIRANGLIAISLEDGDQLRWVRRARAEDSVMIGSRKGMVIHFKT--LRPLGRPTRGVKAMSLR--
-ELISMDILPAGPWVLVITTGGYGKRVPVGQFRLQNRAGMGLVASKF--A-DDQLADLRVVG-GAELMMITSRGIIIRQVTDAISCQSRMATGVRVQRLD
-EAIAAVALVP-
>tr|K9RP03|K9RP03_SYNP3 DNA gyrase subunit A OS=Synechococcus sp. (strain ATCC 27167 / PCC 6312) GN=gyrA PE=3 SV=1
TKDLIANEKSVILVTQQGYIKRMPVDTFESQSRDGRGRKGAQI-EDDGVEHFFGCNDHDQILFFSDRGVVYGLPAYQIPIGSRNARGTPLVQMLPIPREE
KITSVIAVQ---EDEYLVMLTTKGYIKKTALAAFSNIRSNGLIAISLEEGDQLRWVRRAKVSDSIIIGSRAGMAIHFRA--LRPLGRATRGVKSMALR--
-DLVGMDIIPAGPWVLVVTTNGFGKRVPVNQFRLQNRAGLGLMATKFKTT-ADQLAALRVVN-DDELMIVTSRGIIIRQAVNVISSQSRLATGVRLQRLD
-DVIVTAAIVP-
>tr|A0A0M1JYA1|A0A0M1JYA1_9CYAN DNA gyrase subunit A OS=Planktothricoides sp. SR001 GN=gyrA PE=3 SV=1
ETDLIANEKAIILLTKQGYIKRMPVNTFEAQNRATRGKAGTKM-DNDMVEHFLTCCDHDKVLFFSERGVVYCLNAYQIPMSSRTAQGSAIVQLLPIPHDE
KITSIVPVS---DDEYLVMLTQDGYIKKTALSVFNNIRANGLIAISLEEGDQLRWVRRATAEDSIIIGSSNGIAIHFKT--LRPLGRNTRGVKSMKLA--
-RIISMDIIPSGQMVLILTTGGLGKRVPVNKFRLQKRAGKGIKAIKF--P-DDRLAALRVVN-DDEFIIVTSRGIIIRQVAKAISCQSRAAGGVRVQRLD
-DAIVAVALVP-
>tr|B8HKE2|B8HKE2_CYAP4 DNA gyrase subunit A OS=Cyanothece sp. (strain PCC 7425 / ATCC 29141) GN=gyrA PE=3 SV=1
TTDLIANQKAVILVTEQGYIKRMPVDTFEAQSRDGRGRKGAQI-EDDAVEHFFACCDHDGILFFSDRGVAYCLKAYQIPIGSRNARGVPIVQLLPIPREE
KITSVVPVD---EDEYLVMLTAGGYIKKTALSAFSNIRANGLIAIALETGDQLRWVRRAREGDSIIIGSRQGMAIHFRT--LRPLGRATRGVRAMALR--
-DLIGMDILPSGPWVLVVTTCGFGKRVPVSQFRLQNRAGKGITATKFRQT-QDQLAALRIVN-EDELMIVTNRGIIIRQSVGAISSQSRAATGVRLQRLD
-ESIAAVTIVP-
>tr|A0A085B917|A0A085B917_9FLAO DNA gyrase subunit A OS=Epilithonimonas lactis GN=gyrA PE=3 SV=1
IEDMIPDEKVVLTISHAGYIKRTLLSEYKVQSRGGVGNRAATT-DEDFLEYIVTATNHEYLLFFTEKGKCFWLRVFEVPEGSKTAKGRAVQNLINIEQDD
KIKAYIRTKK--NQMNVVMITKNGTIKKTSLEAYSR-RTNGVNAIEIRDNDALLGARLTDGNSQIMIATKNGKCIRFP---ARAVGRGSIGVRGISLE--
-DVIGMIVVND--TVLVVSERGYGKRTAVE-YRITNRGGKGVITLNITE-KTGNLIAIQSVT-EDGLMIINKSGVAIRMNMNEMRVMGRNTQGVKVINLK
-KEIAAIAKVE-
>tr|H3NDL6|H3NDL6_9LACT DNA gyrase subunit A OS=Dolosigranulum pigrum ATCC 51524 GN=gyrA PE=3 SV=1
DEDLIEEENIAVTLSHGGYMKRMPISEFKSQNRGGRGVKGMST-DDDFVEQLRICSTHDFLLFFTNKGKVYQAKGYEVPEYGRNAKGIPALNFLNI-DDE
KIQTMISMT--SADRQLFFATRQGTVKRTALSEFEN-RTSGLIAINLKEGDELVNVV-TNG-QSIVMGTHDGYAVHFAE--VRSMGRTATGVRGVRLE--
-GVIGMEILNSDQDVFVVSENGYGKRTVAAEYAIRNRGGKGVITLNIT-D-NGPLVALKTVDT-EDIMMVTDQGIMIRFDAQDISQTSRSTQGVRLMRLE
E-RVATVAKID-
>tr|K9E947|K9E947_9LACT DNA gyrase subunit A OS=Alloiococcus otitis ATCC 51267 GN=gyrA PE=3 SV=1
DEDLIEEEDIIITLSRKGYIKRMPAGEFKAQNRGGRGVKGMTT-DGDFVEQLTFCSSHDQILFFTNQGKVYKIKAYEIPEYGRNAKGIPAINFLNI-DDE
YIQAMVNLS--DDQDQFFFATRFGRVKRTAQAEFQN-RSSGLNAIKLNEGDELVNVV-THN-QAIILASQQGYAVYFDE--IRSMGRGAAGVRGIRLG--
-DVVAMEVLEPGQDVLVISEKGYGKRTSQEEYTLHKRGGKGVKTLHIT-D-NGPLVGLKTVSG-EDVMIVTDQGIMIRIEADSISQTSRLTQGVRLIRLE
D-RVSTVALID-
>tr|A0A011RR67|A0A011RR67_9LACT DNA gyrase subunit A OS=Alkalibacterium sp. AK22 GN=gyrA PE=3 SV=1
DEDLIEEEEIAITLSHNGYMKRMAISEFKAQNRGGRGVKGMGT-TDDFVETLLTCSTHDLLLFFTNTGKVYKAKGYEIPEYGRTAKGIPAINFLGI-DNE
KIQAIINTR--E-TDQLFFTTRLGTVKRTAFSEFDN-RNNGLKAIVLRDDDELIDVS-THG-DHIVIGTRQGYAVSFHE--VRSMGRSASGVRGMRLR--
-GVVGMDKLSADAEVLIITENGYGKRTPASEYAIRGRGGKGVKTANIT-E-NGPLIGLKTVTM-EDIMLITKSGVIIRFNSSNISQTGRATQGVRLMKLE
G-FVSTLAKVE-
>tr|U1QEE4|U1QEE4_9ACTO DNA gyrase subunit A OS=Actinobaculum sp. oral taxon 183 str. F0552 GN=gyrA PE=3 SV=1
VEDLIPEEDVVVTITRGGFIKRTKVSEYRAQHRGGKGIRGA-FRGDDVVQHFGVASTHAWHLFFTNLGRVYRIKGYELPEAGRDAKGQHIANLLAFQPGE
TIASTITLK---AQ-YLVLATADGRVKKTRLTEYDS-RAGGLIAIRLRETDQVVAAC--NEGDDMLLVSRKGMSLRFTA--LRPMGRPSSGVMGMKFR--
-DLLTMDVVRDNSEVFVVTEGGFAKRTSVAEYRVQGRAGLGVKVAKLT-A-RGDLVGALITE--EDVLVIMASGKVMRASVDEVSR-GRNTQGVTFARPD
-GRIIAIARNV-
>tr|A0A0M5KG26|A0A0M5KG26_9ACTO DNA gyrase subunit A OS=Trueperella pyogenes GN=gyrA PE=3 SV=1
VEDLIPEEDIVVTVTRSGFIKRTRVCEYRAQRRGGKGVKGT-TRSDDVVEHMGIASTHDWHLFFTNLGRVYRVKGYEIPEGSRESKGQHVANVLALQPGE
NIAAAFTLR---AD-YLVLATEDGMVKKTKLSDYDS-RTGGLIAINLRETDQVVSAQ--NEGDELILVSRQGQSLRFTE--LRPMGRATAGVRGMKFR--
-GLLAMEVIRENSEVFVITDGGFAKRTSVDQYRPQNRGGLGIRVAKVV-E-RGHLVGALITQG-DEVVVIMEGGKVVRSFVDEVNL-GRNTQGVRFVRPD
-GHVLAMAPVF-
>tr|D7BLH5|D7BLH5_ARCHD DNA gyrase subunit A OS=Arcanobacterium haemolyticum (strain ATCC 9345 / DSM 20595 / NBRC 15585 / NCTC 8452 / 11018) GN=gyrA PE
DEDLIPEDDVVVTITRSGFVKRTKVSEYRAQHRGGKGIKGT-TRDDDIVEHFEVTSTHDWQLFFTNMGRVYRIKGYELPEGARDAKGQHIANLLAFQPDE
RIASMVSIR---AD-YLVLATEDGLVKKTRLADYDS-RTGGLIAVKLREMDRLVSAR--DDGADVLLVSRGGQSLRFTA--LRPMGRATSGVTGMKFR--
-DLLAMDVVDEGAEVFVVTEGGYAKRTDIEQYRVQGRAGLGIKVANVV-E-RGDLVGALITHG-DEVMVIMESGKVVRSAVDEVSL-GRNTQGVKFATPD
-GKIISIALNL-
>tr|K9EFK9|K9EFK9_9ACTO DNA gyrase subunit A OS=Actinobaculum massiliense ACS-171-V-Col2 GN=gyrA PE=3 SV=1
VEDLIPEEDVVVTITRSGYAKRTKVSEYRSQHRGGKGIKGA-SREDDIVEHFGVGSTHDWHLFFTNFGRVYRVKGYEIPEGGRDAKGQHVANLLAFEPGE
EIAAVRSIP---TD-YIVIATKSGLVKKTRLADYDS-RSSGLIAIKLREPDEVVAVS--NDGDDLFLVSKKGMSLRFTE--LRPMGRATSGVMGMRFR--
-GLLAMDSVRPDSDVFTVTSGGFAKRTPVEEYRVQGRGGLGIKIANLP-E-RGDLVDALVTQS-EEVLVIMESGKVMRTNVTEVST-GRNTQGVTFVRPE
-GSIIALARNV-
>tr|A0A068NHP5|A0A068NHP5_9ACTO DNA gyrase subunit A OS=Actinotignum schaalii GN=gyrA PE=3 SV=1
VEDLIPEEDVVVTVTRSGYVKRTKVSEYRAQHRGGKGIRGA-SRVDDVVDHFGIASTHDWHLFFTNLGRVYRLKGYELPEGGRDAKGQHVANLLAFQPGE
TIAAVRSIR---AK-YLVLATKSGLVKKTPLQDYDS-RSGGLIAIKLRESDEVVAAS--DEADDLLLVSRHGMSLRFTE--LRPMGRAASGVTGMKFR--
-DLLTMDVVHDDSQVFVMTEQGFAKRTSADEYRVQGRNGMGIKVAKLT-E-RGDLVGALMVSG-DEVLAIMESGKVMRAAVDEVSL-GRNTQGVTFVRPD
-GRIIAVARNA-
>tr|D0WL03|D0WL03_9ACTO DNA gyrase subunit A OS=Actinomyces sp. oral taxon 848 str. F0332 GN=gyrA PE=3 SV=1
VEDLIPEEDVVVTITRGGFIKRTKTSEYRAQHRGGKGIKGA-SRGDDVVEHFDVGSTHEWHLFFTNLGRVYRIKGYEIPEAGRDAKGQHIANLLAFQPGE
TIASTITLK---AQ-YLVLATADGLVKKTRLSDYDS-RTGGLIAIKLRE-DHVVAAC--DEDDDLLLVSRKGMSLRFKE--LRPMGRPSSGVTGMKFR--
-GLLTMRVVRDNAEVFVVTEGGFAKRTSVDEYRIQGRAGLGIKVAKLT-E-RGDLVGALITE--EDVMVIMESGKVMRASAAEVSK-GRNTQGVTFARPD
-GRIIAIARNI-
>tr|A0A0K9ETR5|A0A0K9ETR5_9ACTO DNA gyrase subunit A OS=Actinobaculum suis GN=gyrA PE=3 SV=1
VEDLIPEEDVVVTITRGGYAKRTKVTEYRSQHRGGKGIRGA-SREDDVVEHFGVGSTHDWHLFFTNFGRVYRIKGYEIPEGSRDAKGQHVANLVAFEPEE
QIAAVRSIP---AD-YLVIATKSGLVKKTRLTDYDS-RSSGLIAIKLRKTDEVVAVT--NDGDDLFLVSKQGMCLRFTE--LRPMGRATSGVMGMRFR--
-GLLSMDTVRPESDVFTVTTGGFAKRTQIEEYRVQGRGGLGIKVANLP-E-RGDLVDALVTQD-EEVLVIMASGKVMRTTVGEVSI-GRNTQGVTFVRPD
-GEIIAIARNI-
>tr|A0A0J5S3Y9|A0A0J5S3Y9_9PAST DNA gyrase subunit A OS=[Actinobacillus] muris GN=gyrA PE=3 SV=1
LEDLIAQEDVVVTLSHAGYVKYQPLSDYEAQRRGGKGSAT-KMKEDDFIEKLLVANTHDTILCFSSRGRLYQLKVYQLPQASRGARGTPIVNILPLVENE
RITAILTVP--SEDKFIFMATASGTVKKVSLDAFSN-RASGLIALKLREGDELIGVDITDGNSEIMLFSAQGRVVRFAETAVRGMGRVATGVRGIKLAAL
NTVVSLVIPHNQGEILTVTQNGYGKRTALSEYPIKSRATKGVVSI--NE-RNGKVVAAVQVE-NDQIMLITDAGTLVRTRVNEVSLVGRNTQGVRIIRTA
-DQVVSLERIC-
>tr|A0A0G0I7F1|A0A0G0I7F1_9BACT DNA gyrase subunit A OS=Microgenomates (Shapirobacteria) bacterium GW2011_GWE1_38_10 GN=gyrA PE=3 SV=1
DEDLIPNEATLVTLTRGGYIKRVPMETYRTQQRGG-G--TMA--ED-EVENMLFVDTHDDLLIFTNKGRCFKIKVWDINES-RQSKGQAVINLI-NIG-E
T--TVLPIS--NPAKYILLATKHGTIKKTAIEKFKN-R-SGLAAIKLD--DELIW---TD---QVFMATHVGKCI------CRPMGRHTRGVRGITLKE-
-NLVGIDILPQFRHLLIITENGVGKRSDA-LYP-QRRGGLGVKVA---TAKTGNA-AAVVVN-SQQVIFVSKKAVTIKLPL-DIPK-SR---GVILMRLK
D-KVSAMTVLA-
>tr|A0A0G0SRP3|A0A0G0SRP3_9BACT DNA topoisomerase (ATP-hydrolyzing) (Fragment) OS=Microgenomates bacterium GW2011_GWA2_40_6 GN=UU09_C0027G0001 PE=4 SV=1
EEDLIPSEPTLVTITRSGYIKRLPQDTYRTQQRGG-G--SMS--ED-EVESLFNVNTHDNLLFFTNKGRCFKTKVWEIPES-RQSKGQAVVNLI-NVG-E
K--AVLPVA--SDSKFIILATRRGVIKKTAIEKFAN-R-SGLTSIKLD--DQLIW---T---DQIFLATKMGKCI------TRPMGRHTRGVRGITLK--
QDVISMDILPPFRHLMMVTENGVGKRSDV-LYP-QKRGGIGVKVS---SAKTGNA-ATAVVN-TELLILISKKAVTIKLPL-NIPV-SR---GVILMRLK
S-RVNSLTIL--
>tr|F7RYR4|F7RYR4_9GAMM DNA gyrase subunit A OS=Idiomarina sp. A28L GN=gyrA PE=3 SV=1
LEDLIEQEDVVVTLSHQGYVKYQSLKEYEAQKRGGKGAATK-MKDEDFIERLLVANTHDMILCFSSRGRVYWMKTYNLPYASRAARGKPIVNLLPLQ-DE
RINAILPIANFEEDKFVIMATRKGTVKKTPLADYSRPRTSGIIALNLTDGDELIGVDITDGNSEIMLFSDAGKVVRFTEDQVRSMGRTATGVRGMRIE--
PEIVSLLIPRT-GAVLTVTENGYGKRTPLAEYPAKSRATKGVVSIKVSE-RNGAVVGAMEVVPGEHLMLISNRGTLVRTRVDEVSQVGRNTQGVTLIRTA
ADFVVGMAR-V-
>tr|A0A0P7ZNK1|A0A0P7ZNK1_9GAMM DNA gyrase subunit A OS=Idiomarinaceae bacterium HL-53 GN=gyrA PE=4 SV=1
MEDLIDREDVVVTLSHQGYVKYQSLTEYEAQKRGGKGAAT-KMKDEDFIERLLVANTHDMILCFSSLGRVYWMKTYQLPYATRTARGKPIVNLLPLQ-DE
RITAIL--P--EDDKFVLMATRNGTVKKTPLVEYSR-RTSGIIALNLAEGDELIGVDITNGESEVMLFSDAGKVVRFHENHVRSMGRTATGVRGMRIE--
-EIVSLIIPRLESAILTVTENGYGKRTPLADYPAKSRATKGVVSI--SE-RNGAVVGALEVV-GEHLMLISNRGTLVRTRVDEVSQVGRNTQGVTLIRTA
-DFVVGIARIA-
>tr|S9ZJV0|S9ZJV0_9RHOO DNA gyrase subunit A OS=Thauera terpenica 58Eu GN=gyrA PE=3 SV=1
IEDLITPEDMVVTLSHTGYFKRQPLADYRAQHRGGRGQATS-MKDEDFIDHLFVANTHDTVLCFSSRGRCYWLKVYEVPEGTRNSRGKPIVNLFPLN-GE
KITAVLPIKEF--EHFVFMATSEGTVKKTALSAFSNPRKAGIIAVNLDDGDHLIGVAITGGECDVMLFSDAGKAVRFAE-DVRPMGREARGVRGMMLE--
DGVIAMLVAEDLLSVLTATENGYGKRTPVAEYTRHGRGTKGMIAIQTSD-RNGKLVGAVLVEPSDEVMLISTGGVLIRTSVESIREMGRATQGVTLINLD
EGFLASIEKVA-
>tr|W0SFG5|W0SFG5_9RHOO DNA gyrase subunit A OS=Sulfuritalea hydrogenivorans sk43H GN=gyrA PE=3 SV=1
LEDLIVREDMVVTLSHTGYIKRQPLTDYRSQRRGGRGQAAA-IKEDDFVDRLFIANTHDYILCFSSRGRVYWLKVYEAPEGTRNSRGKPIVNLFPLE-GE
KITAILPVKEF--EHFVFMATAMGTVKKTPLTSFANPRKAGIIAVGLDEGDHLIGVAITNGQCDVMLFSDSGKAVRFAE-DVRPMGREARGVRGMMLE--
DEVISMLVADSNYSVLTATENGFGKRTPIAEYTRHGRGTKGMIAIQTSE-RNGKVVAAVLTEPREEIMLISTGGVLIRTRVTDIRVMSRSTQGVTLINLD
DGHLAGVEKVI-
>tr|A0A0C5J9Z0|A0A0C5J9Z0_9RHOO DNA gyrase subunit A OS=Rhodocyclaceae bacterium PG1-Ca6 GN=gyrA PE=3 SV=1
LEDLIVREDMVVTLSHSGYIKRQPLADYRAQKRGGRGQAAA-VKDDDFVDRLFVANTHDYILCFSSRGRVYWLKVYEAPEGTRTSRGKPIINLFPLE-DE
KITAILPVKEF--QHFIFMATARGTVKKTPLTSFANPRKAGIIAVGLDEGDHLIGVSITNGQCDVMLFSDAGKAVRFDE-DVRPMGREARGVRGMMLE--
DGVISMLVADSEWSVLTATENGYGKRTPIAEYTRHGRGTKGMIAIQTSE-RNGRVVAAVLAALREEIMLISTGGVLIRTPVNDIRVMGRSTQGVTLINLD
QGYLAGLEKVV-
>tr|A0A0K1J9X8|A0A0K1J9X8_9RHOO DNA gyrase subunit A OS=Azoarcus sp. CIB GN=gyrA PE=3 SV=1
IEDLIAPEDMVVTLSHGGYFKRQPLADYRAQRRGGRGQATG-MKDDDFIDHLFVANTHDYILCFSSRGRVYWLKVYEVPEGTRNSRGRPIVNLFPLM-GE
KINAVLPVQTF--NHFVFMATAEGTVKKTALTAFANPRKAGIIAASLDDGDRLIGVAITDGESDVMLFSDAGKAVRFPE-DVRPMGREARGVRGMTLE--
EGVIAMLVAKRDLCVLTATENGYGKRTPVAEYTRHGRGTKGMIAIQTSE-RNGRLVGACLVEETDEVMLISTGGVLIRTKVQDIRELGRATQGVTLINLD
ASTLAGIEKVA-
>tr|A0A0A1I3E3|A0A0A1I3E3_9PSED DNA gyrase subunit A OS=Pseudomonas sp. SHC52 GN=gyrA PE=3 SV=1
LGDMIPEEDRVVTISHGGYAKTQPLAAYQAQRRGGKGSATG-VKDEDYIAHLLVANSHTTLLLFSSKGKVYWLKTYEIPEASRAARGRPLVNLLPLD-GE
YITTMLPVEEYTEGHYIFMATANGTVKKTPLESFSRQRSVGLIALELDEGDVLISAAITDGEREVMLFSDGGKVTRFKESDVRAMGRTARGVRGMRLPEQ
K-LISMLIPEEGSQILTASARGYGKRTAISEFPEYKRGGQGVIAMVSNE-RNGRLVGAVQVLDGEEIMLISDQGTLVRTRVDEVSSLGRNTQGVTLIKLA
SDTLVGLERVQ-
>tr|A0A0G0N5K3|A0A0G0N5K3_9BACT DNA gyrase subunit A OS=Microgenomates bacterium GW2011_GWA2_39_19 GN=gyrA PE=3 SV=1
EQDLIAKEETIITLTKTGYVKRVPISTYRAQRRGG-G--VMT--ED-EIAHILSASTHDQIMFFTDHGCVFSIKAWEIAES-RQSKGQAIVNLI-NDG-E
T--AVLPVE--EGAKYLMMATRGGTVKKTPLSAFKN-R-SGLIAIRLE--DSLAW---TD---HVLMATRKGQSI------IRGVGRNTQGVRGVRLTT-
-DVISMEIIPSYRDILVVTENGLGKRTPV-NFP-QKRGGSGVKIA---SDKTGKS-SALMVT-IDQVIITSRSGQVIKLPL-NIPK-GR---GVILMRFG
P-SVAAVALLD-
>tr|C4K6E6|C4K6E6_HAMD5 DNA gyrase subunit A OS=Hamiltonella defensa subsp. Acyrthosiphon pisum (strain 5AT) GN=gyrA PE=3 SV=1
LEDLIPQEDVVVTLSHQGYIKYQPLSDYEAQHRGGKGSAA-RTKDEDFIERLLVANTHDNILCFSSRGRLYWLKVYQLPEASRGSRGRPIVNLLPLN-DE
RITAIL--P--ETGQYVFMATACGVVKKIALLEFSR-RSTGIYTLNLDDGDELIGVDLTDGN-EVMLFSSKGKVIRFSEDDVRAMGRTARGVGGIRLA--
-EVVSLIIPRGDGDILTVTANGYGKKTSKEEYPTRSRNGMGVISI--NG-RNGNVVGAIQVD-NDHLMMITDAGTLVRTRASEMNSISRNTKGVTLIRTQ
-NKVVGLQRLV-
>tr|A0A0D8M3M4|A0A0D8M3M4_PHOPO DNA gyrase subunit A OS=Photobacterium phosphoreum GN=gyrA PE=3 SV=1
LEDLIPREDVVVTLSHEGYVKYQILSDYEAQRRGGKGAAT-RMKQEDFIERLLVANTHDTILCFSSRGRMYWLKVYQLPLASRTARGKPIVNILPLE-NE
RITAIL--P--TEDKFVFMATADGTVKKTPLTDFSR-RSAGIIAVNLREGDSLIGVDVTDGDCDIMLFSAFGKVVRFYESGVRGMGRTAAGVRGIKLA--
-GVVSLIVPHNKGDILTVTENGYGKRTGLDEYPAKSRATQGVVSI--SE-RNGSVVGAVQAE-GDEFMMITNGGTLVRTRVAEVSRVGRNTQGVTLIRTA
-DKVVGLQRID-
>tr|J1QIR7|J1QIR7_9ALTE DNA gyrase subunit A OS=Alishewanella aestuarii B11 GN=gyrA PE=3 SV=1
LEDLITEEDVVVTLSHLGYAKYQPLTDYEAQRRGGRGAAT-TVKDEDFVDKLLVASTHDTILCFSNRGRLYWLKVYQLPLASRTARGKPIVNILPLE-GE
RINAIL--P--EEGKYVFMATANGTVKKTALTEYSR-RSNGIIAVNLNEGDKLIDVGITDGSNEIMLFSDDGKVVRFAEDAVRPMGRGATGVRGIRLR--
-GVVSLIIPQGEGAILTVTENGYGKRTALTEYPTKSRATQGVVSI--SE-RNGLVVGAVQVA-SDEIMMISDKGTLVRTRVREVSEVGRNTQGVILIRTQ
-GKVSGVERIA-
>tr|A0A0F7M758|A0A0F7M758_9GAMM DNA gyrase subunit A OS=Spongiibacter sp. IMCC21906 GN=gyrA PE=3 SV=1
HEDLIPEEERVVTISHNGYAKSQPLDSYQAQRRGGMGSATS-VKEEDFVEHLLVANTHDTILCFSNIGKVYWLKVYQIPVAGRNSRGRPMVNLLP-LDSE
RITSILPVREYTEGYFIFMATEQGTVKKTPLEAFSRRRSVGLRALELDEGDVLIGTAITNGDDDVVLLSSAGKAARFHEGDVRAMGRTARGVRGIRMDEQ
C-VIAMIIPA-GGRVLTVSENGYGKRTPVEEFPCKGRGNRGVIAMTMSE-RNGDLVGAVQVFEGDDLMLISDQGTLVRTRTDEVSQLGRNTQGVRVIRLR
EDHLVGVQRVA-
>tr|A0YDR7|A0YDR7_9GAMM DNA gyrase subunit A OS=marine gamma proteobacterium HTCC2143 GN=gyrA PE=3 SV=1
AEDLITEEDRVVTISHGGYAKTQSLSDYQAQRRGGMGSATA-VKDEDFVEHLMIASTHDTILCFSNVGKVYWLKVFHIPLASRNARGRPMVNLLP-LGDE
RITSILPVKEYTEGHYIFMATANGTVKKTELTNFARQRSVGLRALELEEGDVLIGTAVTNGTCDVMLFSSSGKAVRFNENDVRAMGRTAKGVRGIRMADQ
K-MISLLVPK-GGRMLSVSENGYGKRSEFAEFATKGRGNKGMIFMQASE-RNGEIIGAVQVFDGDELMMISDQGTMVRTRTDEISVLGRNTQGVRVIRLK
EGHVVGVERIE-
>tr|I2JN78|I2JN78_9GAMM DNA gyrase subunit A OS=gamma proteobacterium BDW918 GN=gyrA PE=3 SV=1
HEDLIPEEDRVVTISNGGYAKSQPLDTYQAQRRGGMGSATS-VKDEDFVEHLLVVNTHTTILCFSNIGKVYWLKVYQIPVAGRNSRGRPMVNLLP-LGDE
RITSILPVNEYTEGYFIFMATGLGTVKKTPLEAFSRQRSVGLRAIELDEGDVLIGTAITNGENDILLLTSAGKAARFAEQDVRAMGRTARGVRGIRMDEQ
R-AIAMIIPQ-GGCVLTVSENGYGKRTLVEDFPAKGRGNRGVIAMAMSE-RNGPLVGAVQVFEGDDLMLISDQGTLVRTRTDEVSILSRNTQGVRVIRLK
EDHLVGVQRVD-
>tr|Q21IS1|Q21IS1_SACD2 DNA gyrase subunit A OS=Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) GN=gyrA PE=3 SV=1
HEDLISEEDRVVTISHGGYAKSQPLDAYQAQRRGGMGAATS-VKDEDFVEHLLIANTHDYLLCFTSVGKVFWLKVYQIPVAGRQSRGRPVVNLLP-LEGE
RITSILPVREFDDDHFIFMATADGTVKKTPLSQFARPRSVGLRAIDLVEGDHLVGTAITDGTKDIILLTSAGKAARFSEENVRSMGRVSRGVRGVRMADV
S-VIAMVVPE-GGKVLTVSENGFGKRTEVTEYPAKGRGSQGVIAMQMSE-RNGCLVGATQVFEGDEIMLISNQGTLVRTRADEVSLSGRNTQGVRLIRVK
EGHIVGLERID-
>tr|H5UUP9|H5UUP9_9MICO DNA topoisomerase (ATP-hydrolyzing) OS=Mobilicoccus pelagius NBRC 104925 GN=MOPEL_130_00640 PE=4 SV=1
APLEIGDDPCFALLSGTGLLARTTDRSSFP---------A----KSDDVVAAVPTTARGEIGLLTSTGRVVRIPVLELPTP-PTN-----ASYVD--N-E
V--TILGLD--AGRPGVALGTAGGVVKRVVP-DYPS---DEFEIITLK-GDSVVG---V--TEELVFVTSEAQLL------V---GRAASGVAGIKLGK-
-AVVAFGAYDPT-VVVTIAGSSSVKVTPVE-----GRATGGVRAH--TGEV---L-PVRAVT-GKALALPDGSGVSSPGVVGGTATGG-SAPG-------
G---AALPGLE-
>tr|A0A0Q6T720|A0A0Q6T720_9BURK DNA gyrase subunit A OS=Pelomonas sp. Root1217 GN=ASC95_17790 PE=4 SV=1
TEDLITPTDMVVTLSHTGYIKSQALSEYRAQKRGGRGQATQ-TKDDDWVDQLFIANTHDWLLCFSNRGRVYWLKVWEVPQGSRNSRGKPIVNMFPLQ-DE
KITVVLALTSF--DHFIFMATAMGTVKKTSLKDFSNPRKAGIISVDLDEGDHLIGAALTDGHHDVMLFSDGGKAVRFDEDDVRPMGRTARGVRGMMLE--
PDLIAMLVAEDTQSVLTATENGFGKRTSIVEYTRHGRGTKGMIAIQQSE-RNGRVVAATLVRPEDEIMLITDKGVLVRTRVSEIRELGRATQGVTLIALD
DGKLSGLQRIV-
>tr|I4A283|I4A283_ORNRL DNA gyrase subunit A OS=Ornithobacterium rhinotracheale (strain ATCC 51463 / DSM 15997 / CCUG 23171 / LMG 9086) GN=gyrA PE=3 SV
IEDIIPDEKMVLTISHLGYIKRTPLTEYRAQSRGGVGNKAATS-DGDFLEYMVVASNHQYMLFFTEKGRCFWLRVFEIPEGSKTSKGRAIQNLISIEQDD
KVRAYIRTHM--KNQFVVMLTKNGQIKKTSLEAYSR-RANGINAITIKDDDELLEAKLTDGNSQIMIAAKGGKAIRFD---VRPMGRTASGVRGIRLD--
-DAIGMVVVTD--TILVVSEKGYGKRTSIE-YRTTNRGGKGVITLNITE-KTGNLIALKNVT-DNDLMIINKSGVAIRTAVSELRVMGRATQGVKLINLK
-GEIAAVAKVE-
>tr|F0NXY6|F0NXY6_WEEVC DNA gyrase subunit A OS=Weeksella virosa (strain ATCC 43766 / DSM 16922 / JCM 21250 / NBRC 16016 / NCTC 11634 / CL345/78) GN=gy
IEDLIPDDNVVLTISHLGYIKRTPLTEYKKQSRGGVGNRAATT-DEDFLEYIVVATNHQYMLFFTEKGKCFWLRVFEIPEGSKTSKGRAIQNLINIEPDD
KVKAYILTHM--NNNYVIMVTKNGIIKKTSLEAYSR-RINGINAITIREDDTLLEALLTDGKSQIMIATKYGKAIRFE---VRPMGRTASGVRGINLGDK
-NVIGMIVVSD--TVLVVSEKGYGKRTSIE-YRETNRGGKGVTTLNITE-KTGKLIAIESVT-DNDLMIINKSGVAIRTGLSEIRVMGRATQGVKLINLK
-NEIAAIAKVE-
>tr|A0A0A1CYU0|A0A0A1CYU0_9MICC DNA gyrase subunit A OS=Arthrobacter sp. PAMC25486 GN=gyrA PE=3 SV=1
MEDLIPEEEMVVTITRGGYVKRTRSDNYRTQHRGGKGVKGA-QRGDDVVEHFFVTTTHHWLLFFTNLGRVYRAKAYELVEAGRDAKGQHVANLLAFQPDE
KIAQVMELK---SP-YLVLATKNGLVKKTSLEDYDT-RSAGVIAINLRDGDELVSAQ--SDADDLLLVSRKGQSIRFTE--LRPMGRATSGVTGMKFR-F
-DLLSASVVSDESYVFIVTEGGYAKRTAVGEYRLQGRGGLGIKVAKLV-E-RGDLIGALIVQE-DEVLVVMGGGKVVRSNVSEVPA-GRDTMGVIFAKPD
-NRIIGIARNT-
>tr|G5EP16|G5EP16_9MICC DNA gyrase subunit A OS=Rothia mucilaginosa M508 GN=gyrA PE=3 SV=1
MEDLIPEEEVVVTITRGGYIKRTRSDQYRSQHRGGKGIKGA-SRGDDVVEHFFVTTTHSWILFFTNLGRVYRAKGYELQEAGRDAKGQHIANLLEFQGGE
HIAQVMELK---AE-YLVLATRGGMVKKSRLSDYDT-RTAGLIAINLREGDEVVSAF--SDKDDILLVSRNGMSLRFHA--LRPMGRSTSGVTGMKFR-G
-DLISANVVTEGSFVFVVTEGGYAKRTSVDEYRVQGRNGFGIKVAKLV-E-RGALVGGLIVDE-DEVLVVMASGKVVRSNVNEVPA-GRDTMGVIFAKPG
-GSIIGVARNQ-
>tr|A0A078MLN9|A0A078MLN9_9MICC DNA gyrase subunit A OS=Arthrobacter sp. 11W110_air GN=gyrA_1 PE=3 SV=1
MEDLIPEEEMVVTITRGGYVKRTRSDNYRAQHRGGKGIRGA-QRGDDVVEHFFVTTTHHWLLFFTNLGRVYRAKAYELAEGGRDAKGQHVANLLAFQPDE
HIAQVLDLP---AP-YLVLATKRGLVKKTRLADYDT-RSAGVIAINLRDEDELVSAQ--SETDDLMLVSRKGQSLRFTE--LRPMGRATSGVTGMKFR-D
-DLLAADVVTEDSFVFTVTEGGYAKKTSVEEYRVQGRGGLGIKVGKFV-E-RGHLVGAMVVQG-DEVLVVMQGGKVVRSAVNGVNA-GRDTMGVIFAKPD
-NRIIAVARNS-
>tr|U7V512|U7V512_9MICC DNA gyrase subunit A OS=Rothia aeria F0184 GN=gyrA PE=3 SV=1
MEDLIPEEEMVVTITRGGYVKRTRSDQYRSQHRGGKGIRGA-QRGDDVVEHFFVTTTHNWILFFTNMGRVYRTKAYELLEAGRDAKGQHVANLLAFQPGE
TIAKVMELR---AP-YLVLATKGGLVKKTRLSDYDT-RTAGLIAINLREGDEVVSAF--SPNEDILLVSRQGMSLRFNE--LRPMGRSTSGVTGMKFR-G
-DLISANVVTEDSFVFVVTEGGYAKRTSVNEYRVQGRNGYGIKVAKLV-E-RGALVGALIVDD-DEVLVVMQGGKVVRTGVSEVPA-GRDTMGVIFAKPG
-GSIIGVARNQ-
>tr|K0A7L5|K0A7L5_EXIAB DNA gyrase subunit A OS=Exiguobacterium antarcticum (strain B7) GN=gyrA PE=3 SV=1
DEDLIPEKDIIITLTSSGYIKRLTTDSYRAQRRGGRGVQGIGT-DADYVTRLLSCSTHDTILFFTNRGKVYRIRGYEVPES-RTSKGVPIINLIQIER-E
KVETMIPVNL-DEQKSLIFMTRKGRVKRSPLSAYAR-NKNGLIAIRLFEDDELTSVR-AST-DEVFTVSNSGKAIRFPI--VRSMGRGARGVKAMNLS--
-DVIGMELARD-QDVLVITEKGFGKRTPMTEFRTQSRGGKGLIASKVT-E-VGQIVALRIV-V-DDIMIMTESGIVIRTDSQNISSVGRNAQGVKVIRIE
GD-VATVAKLK-
>tr|S3FC81|S3FC81_9BACL DNA gyrase subunit A OS=Exiguobacterium sp. S17 GN=gyrA PE=3 SV=1
DEDLIPVRDMMIALTSEGYIKSIPSDSYRTQRRGGRGKQGMGT-DEDFVLRLLSASTHDTILFFTNFGRVFRLKGYEIPES-RTAKGMPIINLLQVDK-E
KVETMIPVDL-DEQLSLVFITKHGLVKRSPLSAYAR-NKNGLRAISLNDSDELVTVR-AKS-DEMLIVTHAGMSIRFPL--VRSMGRTARGVRAIRLK--
DDVVSMEIVRP-QDVLIITEKGYGKRTAMEQFRTQGRGGSGIIGIKT--D-RGTVVGMRVV-E-DDIMLMTELGVAIRIDAQTISQMGRSTRGVKVMNIE
GD-LATIAKLK-
>tr|A0A0A8HMG3|A0A0A8HMG3_STAHY DNA gyrase subunit A OS=Staphylococcus hyicus GN=gyrA PE=3 SV=1
DEDLIPEEQIVITLSHKNYIKRLPASTYRSQHRGGRGVQGMNT-EDDFVSQLVTTSTHDHILFFTNKGRVYKLKGYEVPELSRQSKGIPIVNAIELDS-E
KISTMIAVK---EENFLVFATKKGLIKRSALSNFNR-NKNGKIAINFRDDDELVAVR-TDG-KHILIGTSDASLIRFKE--VRAMSRIASGVRGIRLR--
-EVVGLGVADEEDEVLVVTEKGYGKRTSVSEYRVSNRGGMGVKTAKLT-E-NGQLISIGTVSD-EDIMVVTNHGVIIRMEVQDISKNGRMAQGVRLIKMA
D-FVSTVAKVK-
>tr|A0A0M2SKB0|A0A0M2SKB0_9STAP DNA gyrase subunit A OS=Salinicoccus sp. SV-16 GN=gyrA PE=3 SV=1
DEDLIPEEQIVVTLSHNNYIKRLPSSTYRAQHRGGRGVQGMNT-EDDFVSQIVTMSTHDYIMFFTNKGRVYRLKGYELPELSRQSKGIPIVNMLEIDK-E
KISTMIAVKE-FENMFLVFATKNGLVKRSGLENFER-NKNGKIAISFRGDDELLAVR-TDG-KEVILGTKYGALIRFPE--IRTMGRTAAGVKGIRLR--
-DVVGLDVLAE-QSILVVTDNGYGKLTPEAEYRITNRGGVGVKTANLT-D-VGELIYIASVND-EDLMIVTNHGVIIRLVMEEVSVLGRNTQGVRLIKLS
D-KVATVAKVK-
>tr|B9E905|B9E905_MACCJ DNA gyrase subunit A OS=Macrococcus caseolyticus (strain JCSC5402) GN=gyrA PE=3 SV=1
DEDLIDEENIVITLSSNNYIKRLPASTYRAQHRGGRGIQGMNT-DEDFVSQMVTTSTHDNVLFFTNKGRVYKVKGYEIPELSRQSKGIPIVNVIDLDK-E
SISTMIAVK---EDAYIVFATKHGLIKRSNLSHFSR-NKNGKIAINFREEDELIAVR-TDG-KQLIIGTKHASLIRFEE--LRPLGRTAAGVKGISLR--
-GVIGLDVIESEHEVLVVTENGYGKRTKESEYRISNRGGKGIKTATIT-E-NGNLVCITTVNN-EDIMIVTDHGVIIRLDVAEFSQNGRSAQGVRLIRLD
G-FVATVAKVE-
>tr|R7FCX1|R7FCX1_9FIRM DNA gyrase subunit A OS=Ruminococcus sp. CAG:330 GN=gyrA PE=3 SV=1
IEDLIPVEDCVVTYTDSGYIKRISVDAYKSQRRGGRGVTGMKQ-EEDFVSELMISSSHANILFISNLGVMYKLKCYELPES-KNARGTNIINLLPLSAGE
KIAAVLTTP-F-EGKYVVMITRAGKIKRTALSAYKNVRKNGLIAIGLDEGDEIAAVRLTNGSNRLFAATRKGMAIRID---VRPMSRSAHGVKAITLR--
-SVVSMARER-GASLLTVTENGYGRRTALDEYRMQSRGGLGLTNYKVDA-EHGDVCGIKVVD-D-DLMFISSDGVIIRTPCDQIRL-GRVAKGVRVMRVN
-GRVVAFTRTE-
>tr|R7NLL0|R7NLL0_9FIRM DNA gyrase subunit A OS=Eubacterium sp. CAG:581 GN=gyrA PE=3 SV=1
IEDLIPVEDCVVTLTQFGYIKRIPADTYKIQNRGGRGVSGMSR-EEDVAKEMFVVNSHDLILFFTDKGKVYKIKCYEIPE-SRQSKGMNIANLLPIDQDE
KVTSMIKVD-MD-DKYLVMVTKQGIIKRIELSAYNTARKGGLIALELNEGDELAWVRMTEGNDNIIVATEKGMAIRFN---IRAMGRQARGVKAMKLA--
-QIVGMCVAQ-DDMILTVSEKGYGRISKSTDYRVQSRGGKGLTNYHTE--KYGKVAVLQSVN-DDDIIMISQSGIVIRIETSSVRI-NRPSKGVTLMRIG
EDKVVTIATTP-
>tr|R6CGH7|R6CGH7_9FIRM DNA gyrase subunit A OS=Ruminococcus sp. CAG:579 GN=gyrA PE=3 SV=1
VEDLIPVEENVVTYTNSGYIKRMPVSTYKAQNRGGKGVSGMKQ-EDDFVEEMYICSSHDNLLFISNFGIMYKLKCYELPES-KASKGTNIVNILPLKENE
KIAAMIKTS-F-EGKAIVICTKNGKIKRTDLSAYKNVRKQGLIAIGLDEGDEIAGVRMTGGDSQLIVATRMGMAIRIK---IRNMSRSAHGVKAITLR--
-SVVSMARVR-GASVLTVTEGGLGRKTNLDEYRIQNRGGLGLKNYRSGD-D--HVCGIKVID-D-DIIMIASDGVVIRLRASDIRP-SRYARGVRLMKLS
-EKVVAFTRAE-
>tr|R5V915|R5V915_9FIRM DNA gyrase subunit A OS=Ruminococcus sp. CAG:254 GN=gyrA PE=3 SV=1
IEDLIPVEDCVVTFTESGYMKRMPVDVYKTQRRGGRGVSGMKQ-EADFVNEMFISSTHDHILFISNYGMMYRLKCYEIPES-KASRGFNIVNLLPLKEGE
KIAAMLRTK-F-EGKYLVTVTRQGKIKRTALPAYKNVRKNGLIAVGLEEGDEIAGVRLTDGSARLFVATKHGMIIRME---IRPQGRSAHGVKAITLR--
-VVVSIARER-GASLLTVTENGYGRRSELEQYRIQNRGGYGLQNYKVDA-ERGMVCGIKVVD-D-DILLISTDGIVIRVYCADIRL-GRTAKGVRIMRVT
-EQVVAFSRTE-
>tr|A0A0C5VQA8|A0A0C5VQA8_9GAMM DNA gyrase subunit A OS=Gynuella sunshinyii YC6258 GN=gyrA PE=3 SV=1
MEDLITEEDMVVTISHGGYAKSQPLADYQAQRRGGRGAATQ-VKDEDYVAHLFVASTHTTIMCFSDRGKVYWLKVWEIPQAGRTAKGRPLINILNLD-NE
RVTAVLPIEGYEANKFVFMVTAKGTVKKTALEAFSRQRSSGLIALSLDEGDQLVGVAITDGSHEILLLASNGKAVRFSEERVREMGRTARGVRGIRLGEA
E-VISLMIPD-EGTILTVSEKGYGKRTKTQDFPTKGRGTQGVIAMIVND-RNGPLVGAVQIFEGDEIMLISDKGTLVRTRSSEISVLGRNTQGVRLIKVA
EDSLVGVERVE-
>tr|I4ALE9|I4ALE9_FLELS DNA gyrase subunit A OS=Flexibacter litoralis (strain ATCC 23117 / DSM 6794 / NBRC 15988 / NCIMB 1366 / Sio-4) GN=gyrA PE=3 SV=
IEDLIAEQEMVITISNEGYIKRTSLTEYKSQARGGKGSKGATT-ADDFAEHLFIASTHNYLLIFTDHGKVYWLKVYAIPEGSKTSKGRPLQNLISIESGE
KVQAVINVKK--NNNNLIFCTKKGQIKKTILEAYSR-RQNGINAITINEGDALLDVRLTDGSNEIIMAVGSGRAIRFN---VRPMGRTASGVRGISVK--
-DVIGMVCLSR---LLVVSEKGYGKRSDID-YRVIKRGGKGVTTLKITE-KTGALISIKEVI-TDHLMISRKSGVMIRFAVSELRTMGRATQGVRLINLA
-GQIASVAKIE-
>tr|A0A0Q5MZI8|A0A0Q5MZI8_9BURK DNA gyrase subunit A OS=Acidovorax sp. Leaf160 GN=ASF94_15240 PE=4 SV=1
TEDLITPTDMVVTLSHTGYIKSQPLSEYRAQKRGGRGQATA-TKEDDWIDQLFIANTHDYILCFSNRGRLYWLKVWEVPAGSRGSRGRPIVNMFPLQ-GE
KINVVLPLTTF--DRFVFMSTSMGTVKKTALDEFSNPRKGGIIAVNLDDGDYLIGAALTDGKHDVMLFSDGGKAVRFDENDVRPLGRAARGVRGMMLE--
EGVIAMLVAEDTQSVLTATENGYGKRTSIVEYTRHGRGTKGMIAIQQSE-RNGKVVAATLVHADDEIMLITDKGVLVRTRVSEIRELGRATQGVTLIALD
EGKLGGLQRIV-
>tr|A0A016XIE5|A0A016XIE5_9BURK DNA gyrase subunit A OS=Hylemonella gracilis str. Niagara R GN=gyrA PE=3 SV=1
TEDLIAPEDRVVTLSHAGYIKSQPLSEYRAQKRGGRGQATQ-TKEDDWIDQLFIANTHDYILCFSNRGRLYWLKVWEVPEGSRTSRGRPIVNMFPLA-GE
KITVVLPLTRF--DHYVFMATSMGTVKKTTLDEFNNPRKAGIIAVDLDPGDYLIGAALTDGQHDVMLFSDGGKAVRFDENDVRPMGRNARGVRGMLLD--
DGVIAMLVAQSRTSVLTATENGYGKRTPISEYTRHGRGTKGMIAIQQSE-RNGKVVAATLVHADDEIMLITDKGVLVRTRVSEIREMGRATQGVTLIALD
DGQLSGLQRIV-
>tr|A0A0N1LBU0|A0A0N1LBU0_9PROT DNA gyrase subunit A OS=beta proteobacterium AAP99 GN=gyrA PE=3 SV=1
TEDLIAPEDRVVTLSHAGYIKSQALTEYRAQKRGGRGQAAA-MKEDDWIDQLFIANTHDVILAFSNRGRLYWLKVWEVPEGSRTSRGKPIVNMFPLA-GE
KITIVLPLDTY--DRYVFMTTKLGTVKKTPLSEFSNPRKAGVIAVDLDEGDYLIGAAVTDGAHDVMLFSDGGKAVRFDENDVRPMGRTARGVRGMMLE--
EGVIAMLVAED-QSVLTATENGFGKRTPITEYTRHGRGTKGMIAIQTSE-RNGKVVGATLVHADDEIMLITNTGVLVRTRVAEIREMGRATQGVTLINVD
EGKLSGLQRIV-
>tr|I4MNR3|I4MNR3_9BURK DNA gyrase subunit A OS=Hydrogenophaga sp. PBC GN=gyrA PE=3 SV=1
TEDLITPTDMVVTLSHSGYIKSQPLNEYRSQKRGGRGQATA-TKEDDWVDQLFIANTHDWILCFSNRGRLYWLKVWEVPSGSRGSRGKPIVNMFPLA-GE
KINVVLALTSF--DHYVFMATAGGTVKKTALDEFSNPRKAGIIAVDLDEGDYLIGAALTDSHHDVMLFSDGGKAVRFDENDVRPMGRNARGVRGMMLE--
DGVIAMLVAEDTQSVLTATVNGYGKRTPIGEYTRHGRGTKGMIAIQQSE-RNGKVVAATLVHTDDQIMLITDKGVLVRTRVAEIREMGRATQGVTLISLD
DGELSGLQRIV-
>tr|A0A0Q7A797|A0A0Q7A797_9BURK DNA gyrase subunit A OS=Rhizobacter sp. Root404 GN=ASC76_15165 PE=4 SV=1
TEDLITPTDMVVTLSHTGYIKSQALSEYRAQKRGGRGQATQ-TKEDDWIDQLFIANTHDYILCFTNKGRVYWIKVWEVPQGSRNSRGRPIVNMFPLQ-GE
KVNVVLPLTSF--DHYVFMATAQGVVKKTSLDEFSNPRKAGIIAVDLDEGDFLIGAALTDGKHDVMLFSDGGKAVRFDENDVRPMGRGARGVRGMALD--
DGVIAMLVAEDTQSVLTATENGYGKRTSIVEYTRHGRGTKGMIAIQQSE-RNGKVVAATLVRADDEIMLITDKGVLVRTRVAEIREMGRATQGVTLIALD
QGQLIGLQRIV-
>tr|C7QFM3|C7QFM3_CATAD DNA gyrase subunit A OS=Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897) GN=gyrA PE=3 SV=1
IEDLIPEEDVVVTITRGGYTRRTRTDLYRSQKRGGKGVKGA-QKQDDIVDHFFVTTTHHWLLFFTNKGRVYRAKAHELPDTARDARGQHVANLLAFLPDE
KIAQVLDLR---TP-YLVLATKNGLIKKTPLKDYDS-RSAGVIAINLRE-DELIAAE--SPEDDLLLVSKQAQGLRFTE--LRPMGRATSGVIGMRFR-D
-DLLSMDVVRPDTFLFTATSGGYGKRTAVEMFPLRGRGGLGVIAAKTV-DERGGLVGAAVVDG-DEVMAITLSGGVIRTRVSEVRP-SRDTMGVRVINLG
-GTVLAIARNG-
>tr|A0A0Q8VHI0|A0A0Q8VHI0_9ACTN DNA gyrase subunit A OS=Nocardioides sp. Root79 GN=ASE19_13610 PE=4 SV=1
MEDLIPDEDQVVSITRGGYAKRTRADQYRTQKRGGKGVRGA-SRGDDVVDHFISTTSHHWLLFFTTAGRVYRTKVYNLPEASRDAKGGHVAGLLSFQPDE
SIAQVLAIR---AP-YLVLATKKGLVKKTRLGDYNS-RQAGVIAINFRD-DELIGAE--SSEDHILLVSRKGQSIRFPD--LRPMGRATSGVTGMKFR-G
-DLLSMAVIRAVQYVFSITDAGKAKRTRISEYRVQSRGGIGIKAMKLE-NERGSLVGAFIVVG-DEILSITATGQVVRSPIEDFRP-GRSTQGVNFVTPK
-GTVAVVARSV-
>tr|E6D6Y2|E6D6Y2_PROAA DNA gyrase subunit A OS=Propionibacterium acnes HL110PA4 GN=gyrA PE=3 SV=1
EEDFIPDDDVVVTITRGGYAKRTRTDLYRVQKRGGKGVRGA-SRTDDEVAQLFTTTNHQWILFFTNMGRVYRTKVWQLPEAGRDARGGHVAGLLSFLPDE
KIAQVMTLR---AE-YLLLATRKGMVKKTALKAYDS-RQAGVIAVNFRT-DELIGAE--SAADDVLLISRKGQAIRFSD--LRPMGRATSGVTGMKFR-D
-DLLSMSIIHSDRFVFTATGGGYAKRTAVSEYRQQRRGGVGIKAMALS-EERGSLVGGLVVSA-DEIIAIKTSGQITRSAVSEVPA-GRSTMGVKFVSVR
-DAVSIIAVNP-
>tr|A0A085G9L3|A0A085G9L3_9ENTR DNA gyrase subunit A OS=Ewingella americana ATCC 33852 GN=gyrA PE=3 SV=1
IEDLINQEDVVVTLSHQGYVKYQPLTDYEAQRRGGKGSAA-RIKEEDFIDRLLVANTHDTILMFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLE-NE
RITAIL--P--EEGRHVFMATASGTVKKTALTDFSR-RSAGIIAINLNEGDELIGVDLTDGKDEVMLFSAAGKVVRFSEEAVRKMGRTATGVRGIRLG--
-GVVSLII---DGCILTVTQNGFGKRTESAQYPTKSRATQGVISI--SE-RNGPVVGAIQVD-ADQIMMITDAGTLVRTRVSEVSTVGRNTQGVTLIRTA
-DNVVGLQR---
>tr|J3VU17|J3VU17_9ENTR DNA gyrase subunit A OS=secondary endosymbiont of Heteropsylla cubana GN=gyrA PE=3 SV=1
TEDLINQENVIVTLSYQGYVKYQPLRDYEEQRRGGKGSAA-SIKEEDFIDQLLVANTHETILLFSSRGRIYWMKVYQLPEASRGARGRPIINLLPLE-NE
RITAIL--P--EKGSHVFMATSSGTVKKTPLVEFSR-RSAGIIAMNLDVGDELIGIDLTDGNDEVMLFSAYGKVVRFPENQVRSMGRTARGVRGINLA--
-GVVSLIVPRGNDSILTVTQYGYGKRTLQKEYPTKSRSTQGVISI--NE-RNGKVVCALEVN-SDQIMLITDAGTLVRTRVSEISIIGRNTHGVTLIRTA
-EKVVGLQRVA-
>tr|A0A0B3B2Z2|A0A0B3B2Z2_9ARCH DNA gyrase subunit A OS=archaeon GW2011_AR13 GN=gyrA PE=3 SV=1
EKDLVQEKEVVVTVTDKGYCKRMDVQTYKEQKRGGKGVIG--S-TDDYVKQLITCSTHDNLMFFTTRGRVLWLKAHDIPAAERYSKGKAIVNLLNLRDE-
RVTNVISVK-F--NEDLFMATQKGLVKKIALSHFSKPRASGVKAINLPLDNSDVLIGVVKKGQEVLLATKKGQAIRFNS--VRAMGRASYGVTGIKLG--
-EVVSLEVLDT-AAILTISENGYGKRTAIEDYRKTARAGKGVINL--TD-KTGKIVTTVAVNDEDTIIITTAKGIVIRTTLNNIRVMGRATQGVRIVKLA
-GKVTDLIRVL-
>tr|A0A033UT10|A0A033UT10_STAAU DNA gyrase subunit A OS=Staphylococcus aureus C0673 GN=gyrA PE=3 SV=1
DEDLIPEEQIVISLSHNNYIKRLPVSTYRSQNRGGRGVQGMNT-EDDFVSQLVTLSTHDNVLFFTNKGRVYKLKGYEIPEMSRQSKGLPIVNALEIEK-E
MISTMIAVK---EEDYLVFATKHGTVKRSKLSNFSR-NKNGKIAINFKEGDELIAVR-TDG-KEIIIGTKHASLIRFDE--LRPLGRTAAGVKGITLR--
-DVIGLDVTDEQDEILIVTEKGYGKRTSADQYRISNRGGKGIKTATLT-E-NGNLVCITTVND-EDLMIVTNSGVIIRLHVADISQNGRSAQGVRLIRLG
N-HVATVAKVE-
>tr|A0A0F5AU90|A0A0F5AU90_9GAMM DNA gyrase subunit A OS=Salinivibrio sp. KP-1 GN=gyrA PE=3 SV=1
IEDLINEEDVVVTWSHDGYVKYQVLSDYEAQRRGGKGSAT-RMKDEDFIERLLVANTHDTILCFSTRGRMYWLKVYQLPHASRNARGKPIVNLLPLE-DE
RITAIL--P--EEDKYVFMATAHGTVKKTPLTDFSR-RSAGIIAVNLREGDSLIGAQLTDDSSEVMLFSQFGKVVRFLASTVRAMGRTAAGVRGIQLA--
-NVVSLIVPQENAEILTVTENGFGKRTALAEYPTKSRATKGVVSI--SE-RNGDVVSAIQVC-GDELMMITNAGTLVRTRAEEVSQVGRNTQGVRLIRVS
-DKVVGLQRIE-
>tr|U2EL95|U2EL95_9GAMM DNA gyrase subunit A OS=Salinisphaera shabanensis E1L3A GN=gyrA PE=3 SV=1
TADLIAPEDVVVTLTHEGYVKSQPLDAYRAQRRGGRGSATQ-TKDADFIDKLWVAHTHDTLLCFSSAGKAYWLKVYELPSAGRGARGKPIVNLLPLE-DE
RISQVLPIKDFSTSQNVFFATRNGTVKKTALEQFSRPRSNGIIAIDLRDDDALVGVDLTGGDDELMLFSSGGKVIRFAERDVREMGRNAAGVRGIRLPEE
ADVIALIV-IRDGDILTVTEQGYGKRTPVGDYPLRGRGGQGVLSLKQSD-KSGAVVGATQVLEDDEIMLISNMGTLIRTAVAEISVLGRNTQGVRIIRVA
DDHLVGVDRII-
>tr|R4V4A2|R4V4A2_9GAMM DNA gyrase subunit A OS=Spiribacter salinus M19-40 GN=gyrA PE=3 SV=1
MEDLIPEQDVVVTLSHGGYAKSQPIDVYQAQRRGGKGAATR-MRDEDFVDKLWIANSHDTLLCFSSHGKCYWLKVYELPHGSRGSKGKPIVNLLPLE-DE
RINAVLPVSEFDGDYHVFMATQQGTVKKTPLSHFSRPRSSGIIAVHLADGDRLVNVGMTDGNSDIMLLTSAGKAIRFEESKVRAMGRTAAGVRGVRLAPQ
T-VIECLILG-EGHVLTVTENGFGKVTPVADYPLRGRGGMGVIGIQTSE-RNGAVVGAAQVSEDDEVMLISNGGTLVRTRAAEISVLSRNTQGVKLISLG
RGHLVGLARIE-
>tr|U5T5V6|U5T5V6_9GAMM DNA gyrase subunit A OS=Spiribacter sp. UAH-SP71 GN=gyrA PE=3 SV=1
MEDLIPPQDVVVTLSHSGYAKSQPLDTYQAQRRGGKGAATQ-MRGEDFVDKLWVANTHDTLLCFSSRGKCYWLKVYELPHGSRGARGKPIVNLLPLE-DE
RINAVLPISEFDADRFVFMATRQGTVKKTPLVDFSRPRANGIIAVNLGDDDTLVNVGVTDGNREIMLLTDAGKAIRFNESEVRAMGRTATGVRGVRLGTQ
V-VIQSLILE-EGDVLTVTGNGYGKLTPVADYPLRGRGGMGVIGIQTSE-RNGAVVGALQVNQDDEIMLITNGGTLVRTRAAEVSVLSRNTQGVKLIALS
EDTLVGLAKVE-
>tr|A0A084IHP5|A0A084IHP5_9GAMM DNA gyrase subunit A OS=Salinisphaera hydrothermalis C41B8 GN=gyrA PE=3 SV=1
TADLISPEDVVVTLTHEGYVKSQPLDAYRAQRRGGRGSATT-TKDADFIEKLWVTHTHDTLLCFSSYGKAYWLKVYELPSAGRGARGKPIVNLLPLE-DE
RISEVLPIKDFNTDENVFFATRNGTVKKTALEQFSRPRTNGIIAIDLRDDDALVGVDRTAGNDTIMLFSSAGKVIRFAEADVRQMGRNAAGVRGIRLPED
DTVIGLIVVR-EGEILTVTEHGYGKRTPVDDYPLRGRGGQGVLALKQSD-KTGAVVGATQVSEDDEIMLISNMGTLIRTAVSEVSVLGRNTQGVRIIRVG
DGRLVGVDRIA-
>tr|B5JSE9|B5JSE9_9GAMM DNA gyrase subunit A OS=gamma proteobacterium HTCC5015 GN=gyrA PE=3 SV=1
VEDLINEQDVVVTLSHAGYAKAQPLDDYKAQKRGGRGSATK-MKDEDFIEKLFVACTHDTLLCFSSYGKVYWKKVYELPIGSRNARGKPIVNLLPLE-GE
RISAVLPVREFTDDEFVFMATANGTVKRTALSNFSRPRSNGIIALDIRDGDRLVGVARTDGQRDIMLFADSGKAIRFNEQDVRPMGRTAAGVRGIRLSDQ
T-MVGLIIVE-DGDILTATVNGYGKRTAIEDYPTQGRGGSGVLSIKTSD-RNGGVVGAVQVATEDEIMLISNGGVLVRTAVEDISVMSRNTQGVRLIRLD
DKQLVELERIP-
>tr|I3CH81|I3CH81_9GAMM DNA gyrase subunit A OS=Beggiatoa alba B18LD GN=gyrA PE=3 SV=1
IEDLIPDEPVVVTLSHEGYVKSQALSLYQAQKRGGKGAATQ-MKEEDFIDKLFIASTHDTILCFTSAGKVYWLKVYELPQAGRNARGKPIVNLLPLE-SE
RVNAVLPVREFTENRYIFMATVSGTVKKTPLTEFSRPRTNGIIALALDEGDQLVNVAITDGQQDVMLFSNHGKAVRFTEDAVRSVGRTARGVRGILLEKD
K-VISLIITE-GGTILTATENGYGKRTPIDDYPTKGRGTKGVISIKTSE-RNGLVVGAVQVQDNDDLMLISNRGTLVRTPVAGISVVSRNTQGVGLIRLV
DELLVGVEKIM-
>tr|A0A0G3G1B7|A0A0G3G1B7_9GAMM DNA gyrase subunit A OS=Thioalkalivibrio versutus GN=gyrA PE=3 SV=1
LEDLIGEEDVVVTLSHAGYVKYQPVADYRAQRRGGRGAATS-FKEEDFIDRLVVANTHDTILCFSSRGRVYWLKVYELPQGSRAARGKPIVNLLPLE-DE
RISTILPVREYDPDHYVFMVTAQGTVKKTPLTDFSRRRASGIIAVDLREGDHLVDVSLTDGTLDVMLVTTAGKAVRFHESDVRAMGRTACGVRGVRMEDQ
R-VIALLNVD-EGSALLATEHGYGKRTRFDEFPVHRRGGQGVIAIQTEG-RNGLLVGAARVLDDDEVMLITNGGTLVRTPIDQIPLIGRNTQGVRLIRLD
EDNLVELARVA-
>tr|A0A0R2FAC6|A0A0R2FAC6_9LACO DNA gyrase subunit alpha OS=Lactobacillus camelliae DSM 22697 = JCM 13995 GN=FC75_GL000823 PE=4 SV=1
DEDLIEEENVVITLTHNGYIKRLPSDEFKAQNRGGRGVQGTGV-DDDFVEHLVTTSTHDMLLFFTNTGKVYRMKGYEVPEYSRTAKGIPIINLLGI-DNE
KIQTVLNVKD-ASDDYLFFVTRNGVVKRTPTREFYN-RKNGLIALNMKDGDELSNVI-TTG-NTIFIGTHLGYSVTFKE--VRSMGRSATGVRGVRLR--
-GVVGSDILKPDSEVFVISEKGYGKRTAASEYPIKGRGGKGIKTANIT-E-NGPLAGVTTVDT-EDIMVITDAGVMIRFNIDTVSQTGRSTLGVRLIKVD
G-KVATMAKLA-
>tr|A0A0R1ZKR0|A0A0R1ZKR0_9LACO DNA gyrase subunit alpha OS=Lactobacillus sharpeae JCM 1186 = DSM 20505 GN=FC18_GL001193 PE=4 SV=1
DEDLIEEEQVVIALTHNGYVKRLPQAEFKTQNRGGRGIQGMGI-DDDFMEHLISTSTHDTLLFFTNKGKVFRSKGYEIPEYGRTAKGIPIVNLLGI-SGE
KIQAVINVP--ENDDFLFFITQNGTVKRTAVSEFAN-RSNGLIALSLRDDDELSNVL-TDG-STIIIGSKSGYSVTFKE--VRSMGRSAAGVRGMNLR--
-GVIGSDVLRPDAHVFVISEQGYGKQTKASEYPIKGRGGKGIKTVNVT-D-NGELAGLTTIND-EDILVVTDAGVMIRFHAKDVSETGRSAIGVRLIRVD
G-KVATMAKVD-
>tr|A0A0R1QQ17|A0A0R1QQ17_9LACO DNA gyrase subunit alpha OS=Lactobacillus manihotivorans DSM 13343 = JCM 12514 GN=FD01_GL001389 PE=4 SV=1
DEDLIEEETVVITLTHNGYVKRLPQSEFKLQNRGGRGVQGTGV-DDDFVEHLISTSTHDVLLFFTNSGKVYRAKGYEIPEYGRTAKGIPIINLLGI-DNE
KIQTVINVN--KRADYLFFVTKHGIVKRTPVAEFLN-RKNGLIALNMKPDDELSRVI-TTG-ATMLIGTHNGYSVTFKE--VRSMGRSATGVRGIRLR--
-DVVGADVLTPDSEVFVVSEKGYGKRTAASEYPIKGRGGKGIKTANVT-E-NGPLAIVTTVND-EDIMAVTDAGVMIRFNIDTVSQTGRATLGVRLMRVD
G-KVVTVAKLA-
>tr|A0A0R1K3M4|A0A0R1K3M4_9LACO DNA gyrase subunit A OS=Lactobacillus nasuensis JCM 17158 GN=FD02_GL001725 PE=4 SV=1
DEDLIEEEDVIIALTHNGYVKRLPQTEFKAQNRGGRGIQGMGV-DDDFMEHLVSSSTHDVLLFFTNNGKVYRSKGYEIPEYGRSAKGIPIINLLGI-ADE
KVQTVINVK--ADNKFLFFVTTGGVVKRTPVAEFLN-RKNGLIALKMREGDTLNNVI-TTG-DTMFIGTHLGYSVTFKE--VRVMGRTATGVRGVRLR--
-GVVGSDILHDTDEVFVVSEKGYGKRTPASEYPIKGRGGKGIKTANIT-E-NGPLAGVTTVAT-EDILAMTDSGVMIRFNIDTVSQTGRATLGVRLMRVD
G-KVVSMAKVD-
>tr|A0A0R2C5J4|A0A0R2C5J4_9LACO DNA gyrase, A subunit OS=Lactobacillus thailandensis DSM 22698 = JCM 13996 GN=FD19_GL001287 PE=4 SV=1
DEDLIEEENVVIALTHNGYVKRVPAAEFKTQNRGGRGIQGMGV-DDDFMEHLISTSTHDVLLFFTDAGKVYRMKGYEIPEYGRTAKGLPIINLLGI-NDE
KIQAVITVP--EGEHYLFFVTKQGVVKRTAVAEFGN-RRNGLIAINLKDDDQLTNVM-TEG-DNILIGTHNGYSVTFNE--VRGMGRSAAGVRGIRLR--
-GVVGSDIMRPGSDVFIISEKGYGKRTPVSEYPVKGRGGKGIKTANVT-T-NGPLAGVTTVDT-EDILVVTDAGVMIRFRSGSVSQTGRATLGVRLIRVD
D-KVASMAKVE-
>tr|A0A0R2FZS3|A0A0R2FZS3_9LACO DNA gyrase subunit A OS=Lactobacillus selangorensis GN=IV38_GL000820 PE=4 SV=1
DEDLIEEEDVVITLTHNGYIKRQPARDFKSQNRGGRGIQGMGV-DDDFTEQLISTTTHHVLLFFTNTGKIYRMKGYEIPEYSRTAKGIPVINLLGI-NDE
KIQTVISVSE--DKNDLFFVTKNGTVKRTAVSEFAN-RKNGLRALMLKDDDELTNVL-TDG-QNIIIGTHLGYAVSFKE--VRQMGRSATGVRGIRLR--
-NVVGSDILHPNADVFVISEKGYGKRTPVADYPIKGRGGKGIKTTNIT-E-NGPLAGLTTVNS-EDILVMTNTGVMIRFSSSDVSQTGRSTLGVRLIRLD
N-IVVSMARVL-
>tr|A0A0Q9YJJ2|A0A0Q9YJJ2_9COXI DNA gyrase subunit A OS=Coxiellaceae bacterium CC99 GN=gyrA PE=4 SV=1
REDLIPEETRVVTLSHFGYVKTQPLDSYVAQRRGGRGAAAT-VRDEDFIEKLLIANTHDTILCFSDKGKVYWLKVYDLPLGNRQSKGKPIVNFLPLT-DE
KISAILPIKEFAEGSYVFMATRMGTVKKVDLLDFSRPRASGIIAVDLEEEDSLVGAELTDGARDVMLFTNAGKAVRFHEDTVRAMGRLAKGVRGIRLQE-
-QVVSMIVLGEYQSLLIATENGFGKRTLVEEFPVKGRGGQGVISIQTTE-RNGQGVGARGIRDKDEAMLISDGGILVRLRTDEISLVGRNTQGVTLINLG
EGKLIGLERVE-
>tr|A0A0Q9Z0P8|A0A0Q9Z0P8_9COXI DNA gyrase subunit A OS=Coxiellaceae bacterium HT99 GN=gyrA PE=4 SV=1
NEDLISEEMRVVTISHQGYVKTQPLDAYAAQHRGGRGAATS-VKDEDYVDQLLVANTHDTILCFSSKGKVYWLKVYQLPLGSRNSLGKPIINLIPSLENE
RISAILPLREFSDTHCVVMATAQGVIKKVNISEFSRPRSSGIIAVDLDENDELVGAETTDGDRDIMLFTNSGKAVRFHENTVRCMGRIARGVRGVKLQEQ
R-VISLIVVKSDCTILIATENGYGKRTPVSDFPVKGRGGQGVIAIQTTE-RNGNVIGAVQVENNDEIMLITDGGTLVRTRVDEISVVGRNTQGVTLIQLS
NEKLVGLQRIL-
>tr|Q2Y6Z0|Q2Y6Z0_NITMU DNA gyrase subunit A OS=Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849) GN=gyrA PE=3 SV=1
MEDLIASEDVVVTLSHNGYIKSQPLDDYRAQKRGGRGQATG-TKDDDFIDNLFIANTHDYILCFSSRGRVYWIKVYSVPQGGRASRGRPIVNLMQLE-GE
KINAVLPIKTF--NRYVFMATSLGTVKKTPLSEFSRPRASGIIAVGLDEDDFLIGVALTEGKHDVMLFSDGGKAVRFDE-DVRPMGRGARGVRGMTLG--
KGVISLLVAESEQAVLTATENGYGKRTPISEYTRHGRGSQGMIAIKTTQ-RNGKVVGARLVREDDEIMLITTGGVLIRTRVKEVREMSRATQGVILINLD
EGKLAGLERVV-
>tr|A0A0F7KHV4|A0A0F7KHV4_9PROT DNA gyrase subunit A OS=Nitrosomonas communis GN=gyrA PE=3 SV=1
TEDLIAPADVVITLSHAGYIKSQLMDDYRAQKRGGRGLAIT-TKEDDFIDNMFIANTHDYILCFSSLGRVYWVKVYNVPQGSRSSRGKPINNLLQLE-DE
KINAVLPVKIF--NRYIFMATAFGTVKKTPLSEFSRPRNNGIIAIDLDKDDYLIGVALTEGKHDVMLFSDNGKAMRFDE-DVRAMGRSARGVRGMKLG--
AGVISMLVAENELAVLTATENGYGKRTPISEYTRHNRGTQGMIAINTGA-RNGKVVAAQLVKSDDEIMLITTGGVLIRTRVNEIREMGRATQGVTLINLD
QGKLAGLERVI-
>tr|Q0AFR5|Q0AFR5_NITEC DNA gyrase subunit A OS=Nitrosomonas eutropha (strain C91) GN=gyrA PE=3 SV=1
TEDLITPTDMVVTLSHAGYIKSQLLDDYQAQKRGGRGQAIT-TREDDFIDNLFIANTHDFILCFSSLGRVYWIKVYNVPQGSRTSRGRPINNLVPLE-HE
KINAVLPVKSF--TRYVFMATAGGTVKKTPLSEFSRPRTNGIIAVALDEGDYLIGVALTEGKHDVMLFSDAGKAMRFDE-DVRPTGRNARGVRGMKLG--
AEVISLLVADSNMTVLTATENGYGKRTSITEYTRHNRGTQGMIAINTNK-RNGKVVAAQLVEPNDEIMLITTGGVMIRTRVSEIREMGRATQGVILINLD
AGKLAGLERIV-
>tr|Q3SK89|Q3SK89_THIDA DNA gyrase subunit A OS=Thiobacillus denitrificans (strain ATCC 25259) GN=gyrA PE=3 SV=1
MEDLIKPEEMVVTLSHGGYMKSQPLDDYRAQKRGGRGQAAG-TKDEDFIEKMFVANTHDYILCFSNRGRLYWLKVYNVPQGGRAARGKPIVNLLPLE-GE
KISALLPVKTF--EHYVFMATANGIVKKTPLSEFSRPRTAGIIAVGLDDGDVLCGASITDGRHDVMLFSDSGKAVRFDE-DVRPMGRAARGVIGMKLA--
KGLISLLVAEDNDFVLTATENGYGKRTPIAEYTRHARATQGMIAIQTSE-RNGKVVAANLVKADDEIMLITTGGVLIRTRVKEIRAMSRATQGVTLINLD
KGKLISLEKVA-
>tr|E6QX62|E6QX62_9ZZZZ DNA gyrase subunit A OS=mine drainage metagenome GN=gyrA PE=3 SV=1
MEDLITPQDMVVTLSHGGYMKSQPLDDYQAQKRGGRGQAMP-TKEDDFIERLFMANSHDYMLCFSNLGRVYWLKVYEVPQGSRTSRGKPIVNLLPLA-NE
KINAILPVKEF--SRYVFMATALGVVKKTQLSDFSNPRRAGIIAVDLDEGDYLIGVSLTDGQHDVMLFSNSGKAVRFDE-DVRSMGRGARGVRGMKLA--
KDVISLLVAENQQSVLTVTENGYGKRTNIAEYTRHARGTQGIIAIQTTP-RNGGVVAATLVEADDEIMLITDGGILIRTRIREVREMGRATQGVTLIHLD
SGKLIGVERVL-
>tr|F9ZGL0|F9ZGL0_9PROT DNA gyrase subunit A OS=Nitrosomonas sp. AL212 GN=gyrA PE=3 SV=1
MEDLITPADVVVTLSHTGYIKSQLLDDYRAQKRGGRGLATS-TKEDDFIDKLFIANTHDYILCFSSLGRVYWIKVYEVPQGGRQSRGKPIINWVQLE-GE
KINAILPVKTF--NRFVFMATSFGTVKKTPLSEFSRPRNNGIIAIGLDEGDFLIGVELTEGKHDVMLFSDNGKAMRFSE-DVRPMGRTARGVRGMKLG--
PGVISMLVAENDLAVLTATENGYGKRTPISEYTRHNRGTQGMIAIITSA-RNGKVVTAKLVKPDDEIMLITSGGVLIRTRVNEVREMSRATQGVTLINLD
AGKLAGLERVV-
>tr|A0A0R0LHU2|A0A0R0LHU2_9PROT DNA gyrase subunit A OS=Ferrovum sp. JA12 GN=gyrA PE=4 SV=1
MEDLITPEEMVVTLSHDGYIKAQPINDYKAQKRGGRGQAAA-TKEDDFIDRLFVANTHDHVLCFTSLGRVHWLRVFNVPVGSRTSRGKPVNNLLHIE-GE
KINALLPVKVF--EHFVLMATAFGTVKKTPLTDFSRPRSAGIIAVDLDENDYLVGAAITNGEHDVMLFSDDGKAIRFNE-DVRAMGRTARGVRGMRLS--
PNVISMLVAKNEQTVLTATANGFGKRTPIAEFTRHGRGGQGMISIHTSE-RNGSVVSAALVNTSDELMLITSGGVLIRTRVEEIREMSRATQGVTLIALD
KGTLVSLSPID-
>tr|R4YLU8|R4YLU8_OLEAN DNA gyrase subunit A OS=Oleispira antarctica RB-8 GN=gyrA PE=3 SV=1
MADLIPEEDLVLTISHGGYAKTQQMDVYQAQRRGGKGSAAS-VKDDDYVEHLMIANSHDTVLCFTDAGKVFWLKVYDIPQASRNAKGRPMVNVVN-LGEE
RITAILPLPEFTGEEFIFMATSMGTVKKTSLEHFQRPRSSGLIACELDEGDHLIGVAITDGTKDILLLTDAGKANRFNESAVRAMGRTARGVRGIRIQEQ
K-VISLVIPEEGGTLLTASDRGYGKRTLISEFPTKGRGTQGVKAMVVNE-RNGIIVGAVQVFENDEVMLISDKGTLVRTSADSVSCLGRNTQGVRLIKVA
EKRLIGVERVC-
>tr|Q1N5G2|Q1N5G2_9GAMM DNA gyrase subunit A OS=Bermanella marisrubri GN=gyrA PE=3 SV=1
MEDLIAEEDMVVTLSHGGYAKIQPVTDYQAQRRGGRGSASA-IKDEDFIEHLLVANTHDTILCFSNAGKVYWLKVYDIPVASRQSRGRPIVNLLPLE-DE
WITTILPVREYTEGHYIFMATSKGTVKKTDLTAFSRPRSSGLIALELEEGDTLMGAEITDGNQDVLLMSDVGKAVRFAESNVRAMGRTARGVRGIKMQDQ
K-VVSLMIPK-GATVLTASEHGYGKRTDVDEFPTKGRGTQGVIGMVTND-RNGKLVGAVQVFDGNEIMLITNQGTLVRTRVSEVSTLGRNTQGVTLIRVQ
EGRLVGIAPIM-
>tr|A4BJH9|A4BJH9_9GAMM DNA gyrase subunit A OS=Reinekea blandensis MED297 GN=gyrA PE=3 SV=1
MEDLITEEDMVVTISHSGYAKTQPLTDYEAQKRGGKGSASA-LKDDDFIEHLLVASSHDTILCFSTFGKVYWLRVFEIPQASRAARGRPMVNLLPLE-EE
RVTAILPIRNFDPDYFIFMATASGTVKKTSLDAFSRPRSSGLIALSLDEGDHLVGVACTDGEREVMLLSDAGKVVRFKEEHVRPMGRTARGVRGISLEDQ
S-VISLIVPQ-EGFVLTASERGYGKRTVMTEFPTKGRGTKGVIAMVSND-RNGKLVGAKQVFNGDEVMLISDQGTLVRTRVDEISSLGRNTQGVKLIRVA
DDKLVSIERIE-
>tr|W8G066|W8G066_9GAMM DNA gyrase subunit A OS=Thalassolituus oleivorans R6-15 GN=gyrA PE=3 SV=1
TRDLIPEETLVLTLSHGGYAKTQPMDAYQAQKRGGKGSAAS-VKDEDFIEHLLVVNSHDTVLCFTDAGKVYWLTVYDIPQASRNAKGRPIVNVLNLSEGE
RITAILPVPEYSAERYVFMVTARGTVKKTTLDQFSRPRSSGLIACELDEGDHLVGVAITDGTQEILMLSNAGKAVRFKETDVRAMGRTARGVRGIRLGEQ
R-VISLIIPE-NGAILTASERGYGKRTLVTEFPTKGRGTQGVIAMVTSE-RNGALVGAVQVFEGDEVMLVSDQGTLVRTRTSEVSLLGRNTQGVTLIRIA
DKKLVGVERIC-
>tr|B9XGG7|B9XGG7_PEDPL DNA gyrase subunit A OS=Pedosphaera parvula (strain Ellin514) GN=gyrA PE=3 SV=1
LEDLITNEGVIITITHGGLIKRTNVSSYRAQRRGG-G--IMA-RDD-FIEHLFSAGTHDYLMFFTNSGRVFVERVHEIPDA-RASKGRSIANLL-EKE-E
K--ALIRIV-NTQSGELFFATQQGTVKKTSLADFAN-R-GGIIAISIE--DTLID---TK-GEDVVLITREGMSI------VRSMGRNATGVRGINLE--
TDVVALAVLV-DATLLVAGENGIGKRTDF-EYR-QSRGGKGIITM---NDKTGGV-GALTVR-NDEIMLITEAGQMVRISV-DIRE-GR---GVKLINLE
G-KLQAISPVI-
>tr|E4XU22|E4XU22_OIKDI Uncharacterized protein OS=Oikopleura dioica GN=GSOID_T00003996001 PE=3 SV=1
MEDLIANDAMIVTLSHRGYVKRTPATEYRLQGRGG-G--KME-KDD-FVEHLFSVQAHDYLLFFTNTGRVYVERVFELPES-RTSTGRSIKNVL-NKD-E
K--ALLRLEDNEDAGFVFFATRNGKVKKTALNDFRN-R-DGIIAINLD--NDLIG---TD---EIVLVTRDGMSI------IRPQGRATAGVTGIRLRK-
-DVVGMAI---ETMLLVASENGLGKRTAF-SYR-LRRGGLGVKTL---TDKTGKV-NAVSVT--DELMLMTSTGQSIRIRV-EIRE-GR---GVKLLTLK
G-KLQDISLVI-
>tr|B4D634|B4D634_9BACT DNA gyrase subunit A OS=Chthoniobacter flavus Ellin428 GN=gyrA PE=3 SV=1
IEDLIANEGVIVTLTHNGFIKRTAVSAYRAQRRGGKGVIGMTA-DSDFVEHLFTATTHDYLMFFTVEGRCYVERVFEIPEGTRTSKGRSIANVLELRQDE
KIAATIRIQEW---LHIVFATRSGIVKKSNLNEFKNIRKGGIIAIQIETGDRLIDCKLTTGLDEIVLITHEGMSIRFNE--LRDQGRNTVGVWGIRPD--
-YVVAAALVNKEAMLLVAGENGIGKRTGFDEYRIQSRGGKGIITM--TD-KTGSVAGALTVVETDELMLITNKGKMVRTRVAEIRETGRNAQGVKLIDLR
-NILQGIAPVV-
>tr|A0A0P0G3Y3|A0A0P0G3Y3_9BACT DNA gyrase subunit A OS=Candidatus Xiphinematobacter sp. Idaho Grape GN=gyrA PE=4 SV=1
IEDLIVNEGCIITVTYGGFIKRTPVSAYRAQRRGG-G--IMA-RGD-FVEHLFTASTHDYLMFFTKTGRCYVEKVYEIPEG-RASKGRSVANLL-NQG-E
S--ATLRIQNSNASLYILFATESGIVKKSNLVNFSN-R-GGIIAIRIE--NQLID---T---SEVILVTRRGMSI------LRDQGRDTVGVLGIRLE--
GDVVGVAIVR-SATLLVAGENGIGKRTPF-DYR-QSRGGKGVITM---GDKTGYV-GALAVN-RDELMLITTGGQLVRTHI-GIRE-GR---GVKLINLQ
K-KLQAIAPVV-
>tr|I0K0S6|I0K0S6_9BACT DNA gyrase subunit A OS=Methylacidiphilum fumariolicum SolV GN=gyrA PE=3 SV=1
FEDLVANQRVVITLTHNGFIKRTNLDNYRSQRRGG-G--VMA-QQD-FVENLINASTHDYLLFFTTDGRVYIQRVYELPEE-RASKGKNIVNFL-EKT-E
E--SMLRIVVSDKNDYIFFCTKKGRVKKTPVTDFQN-R-GGITAISID--DKLID---TK---EIVLITKEGQSI------VRSMGRNAAGVIGINLRE-
-GVVGAAV---RATLLVVGEKGIGKRTSF-EYR-QKRGGYGIKTM---TEKTGKV-SARTVF--DELMLLTLKGNVIRIKV-DLRK-GR---GVRLVQLD
D-KVTSIARVV-
>tr|R6K1D4|R6K1D4_9BACT DNA gyrase subunit A OS=Akkermansia muciniphila CAG:154 GN=gyrA PE=3 SV=1
IEDLIPNDTMIVTITHSGYIKRTNSAEYRVQARGG-G--KAT-RAD-FIEHLFAAQNHDYLMFFTNTGRVYVDRVYEIDEA-RSAQGRNIKNLL-DQE-E
A--AILRLEEKEGSGNVVFATKDGTVKKTSLNDFAN-R-AGIIAINLE--NSLVN---T---DEIVLVTHDGMSI------LRTQGRNTIGVRGIRPR--
GDVVALAIVD-QKTLLVASENGLGKRTSF-EYR-QGRGGTGIKTM---TDKTGKV-SATVVS-EDELMLMTTAGQSVRIKV-TVRE-GR---GVKLMTLN
G-SIQDISIVI-
>tr|B3DXI4|B3DXI4_METI4 DNA gyrase subunit A OS=Methylacidiphilum infernorum (isolate V4) GN=gyrA PE=3 SV=1
FEDLVANQRVVITLTHNGFIKRTSLDSYRSQRRGG-G--IMS-QKD-FVESLFNASTHDFLLFFTTDGRVYIQRVYEIPEE-RASKGKNIASIL-EKT-E
E--SMLRIVASDKEGYIFFCTLKGKVKKTPVSEFRN-R-GGITAISIE--DKLID---TK---EIVLITKEGQSI------VRPMGRNAAGVIGIDLQP-
-GVVGMSI---RATLLVVSEKGMGKRTSF-EYR-QKRGGQGVITM---SDKTGKV-KAITVL--DELLVLTLKGNVIRIHV-DLRK-GR---GVRLVQLD
E-KVTSIARII-
>tr|Q2L2T2|Q2L2T2_BORA1 DNA gyrase subunit A OS=Bordetella avium (strain 197N) GN=gyrA PE=3 SV=1
TEDLITPMDMVVTMSHGGYIKSQPLSEYRSQKRGGRGQATQ-MKENDWVDQLFIANTHDYLLCFSNRGRVYWLKVWEVPQGTRNSRGKPIVNMFPLA-GE
KITVVLPVKEF--DHYVFMATSRGTVKKTALSDFSNPRKAGIIAVDLDEGDYLIGADLTDGKHDVMLFSDSGKAVRFDENDVRPMGRAARGVRGMMLE--
DSVIALLVAGDSQSVLTATENGYGKRTSIAEYTRHGRGTKGMIAIQTSS-RNGRVVGAVLVNPSDEIMLITTGGVLVRTRVSEIREMGRATQGVTLISVD
DGSLSGVRRVA-
>tr|Q1YRS3|Q1YRS3_9GAMM DNA gyrase subunit A OS=gamma proteobacterium HTCC2207 GN=gyrA PE=3 SV=1
IEDLITEEDRVVTISNGGYAKTQPLSDYQAQRRGGMGSATA-VKDEDFVEHLLVASTHATILCFTNLGKVYWLKVYQIPVAGRNSRGRPVINLLP-LGGE
RISSILPVEEYSADKFVIMATANGTVKKTSLEQYSRPRSVGLRAVDLVEGDHLVGTAIIDDDSDVMLLSSEGKAVRFASTDARSMGRVSKGVRGMRLPEH
E-VISMVVPE-DGFLLTVCENGYGKRTKVDEFPTKGRGGKGMIAIQASE-RNGPLVGATQLFAGDEIMLISDQGTMVRTRGDEVSVVGRNTQGVRIIRLK
DSNLVRLARIA-
>tr|F3KZY9|F3KZY9_9GAMM DNA gyrase subunit A OS=gamma proteobacterium IMCC3088 GN=gyrA PE=3 SV=1
VEDLITPEDRVVTISHGGYAKTQPLSDYQAQRRGGMGSATA-VKDEDFVEHLLVASTHSTILCFTNLGKVYWLKVYQIPVAGRQSRGRPMVNLLPLD-GE
RVTSILPVAEYTEDHYIFMATAKGIVKKTALTDFSRPRSVGLRALELAEDDVLVGTAITHGESDVMLMSSAGKAVRFAEQDVRPMGRTARGVRGIRMGDD
E-MIALIIPQ-GSYVLTASANGYGKKTMASEFPRKGRGTKGVIAMVTND-RNGPLVGAVQVGEADELMLISNQGTMVRTRVSEISTLGRNTQGVRVIRLK
EGELVRITQIE-
>tr|A0A095X374|A0A095X374_9GAMM DNA gyrase subunit A OS=Pseudohaliea rubra DSM 19751 GN=gyrA PE=3 SV=1
VEDLITEEDRVVTISHLGYAKTQPLTDYQAQRRGGMGAALS-VKDEDFVEHLLVASTHATILCFSSLGKVYWLKVYQIPLAGRGSRGRPLVNLLPLE-GE
RVTSILPVEEYTPGHFIFMATAGGTVKKTPLTNFARPRSVGLRALELDEGDVLIGTAITDGNCDVMLFSSGGKVARFSEDDVRPMGRTARGVRGIRLAGQ
Q-MISLVIPR-DGRILTVSEKGYGKRTDVVEFPTKGRGNMGVIAMAQSE-RNGELVGAVQVFDGDELMLISNLGTLVRTRADEVSMLSRNTQGVRIVRCK
DGQLVRVAQID-
>tr|B7RYF2|B7RYF2_9GAMM DNA gyrase subunit A OS=marine gamma proteobacterium HTCC2148 GN=gyrA PE=3 SV=1
VEDLITEEDRVVTISHGGYAKTQPLTDYQAQRRGGMGSATA-VKDEDFVEHLLIASTHATILCFSNLGKVYWLKVYQIPLAGRNSRGRPMINLLPLE-GE
RVTSILPVEDYTEGHYIFMATASGTVKKTALINFARQRSVGLRALELEEGDVLVGTAVTTGDCDVMLLSSEGKAVRFKEGDVRAMGRTARGVRGIKLGDH
E-MISLIIPR-GGRVLTVSENGYGKRTEMSEFPTKGRGTKGVIAMQTSE-RNGTLVGAVQVFDGDQLMLISNQGTLVRTRADEISVLGRNTQGVRVIRTK
TDSLVSVERIE-
>tr|S8GXQ4|S8GXQ4_9BACT DNA gyrase subunit A OS=Bacteroidetes bacterium oral taxon 272 str. F0290 GN=gyrA PE=3 SV=1
PEDFYADDNMVITISHMGYIKRTPLADFRTQNRGGVGSKGSET-DSDFVEHIYPATMHNTMMFFTKKGRCFWLKVYEIPEGTKTSKGRAIQNVLNIEAGD
AVTAYIRIKT--HSHCLMFCTRQGIVKKTLLEQYSR-RTNGINAINILPGDEVIDVCLTLREDEIIIANKNGRAIRFN---VRMMGRTATGVHGMRLD-A
-DVVGMVRIKDQETIMVVSEQGYGKRSEIA-YRLTNRGGKGVKTLNITD-KTGKLIAIKAVT-DHDLMIINKSGITIRLKLADVRIMGRATQGVRLINLE
RNEIASVCKVN-
>tr|F3LUC8|F3LUC8_9BURK DNA gyrase subunit A OS=Rubrivivax benzoatilyticus JA2 = ATCC BAA-35 GN=gyrA PE=3 SV=1
TEDLITPTDMVVTLSHTGYIKSQPLTEYRAQRRGGRGQATQ-TKDDDWIDQLFIANTHDWILCFSDRGRVYWLKVWEVPQGSRNSRGKPIVNMFPLQ-GE
KITVVLPLTSF--DHYVFMSTALGTVKKTPLDEFSNPRKAGIIAVGLDEGDYLIGAALTDGRHDVMLFSDGGKAVRFDEDDVRPMGRNARGVRGMALE--
PGVIAMLVSDRRVSVLTATENGFGKRTPIGEYTRHGRGTKGMIAIQQSE-RNGKVVAATLVRETDEIMLITDRGVLVRTRVAEIREMGRATQGVTLIALD
DGKLSGLQRIV-
>tr|A2SI05|A2SI05_METPP DNA gyrase subunit A OS=Methylibium petroleiphilum (strain PM1) GN=gyrA PE=3 SV=1
TEDLITPTDMVVTLSHTGYVKSQPLAEYRAQRRGGRGQATQ-TKDDDWIEQLFIANTHDWMLCFSNRGRVYWLKVWEVPQGGRAARGKPIVNMFPLQ-NE
KITVVLPLTTF--DHYIFMSTALGTVKKTALDEFSNPRKAGIIAVDLDEGDHLIGAALTDGKHDVMLFSDGGKAVRFDEDDVRPMGRNARGVRGMALE--
PGVIAMLVAEDSQSVLTATENGYGKRTSITEYTRHGRGTKGMIAIQQTE-RNGRVVAATLVRPEDEIMLITDRGVLVRTRVSEIRELGRATQGVTLISLD
DGQLGGLQRIV-
>tr|A0A0N1AEW5|A0A0N1AEW5_9PROT DNA gyrase subunit A OS=beta proteobacterium AAP65 GN=gyrA PE=3 SV=1
TEDLITPTDMVVTLSHTGYVKSQPLTEYRAQKRGGRGQATQ-TKEDDWVDQLFIANTHDWILCFSDRGRVYWLKVWEVPQGSRASRGKPIVNMFPLQ-GE
KVTVVLPLTTF--DHFVFMSTALGTVKKTSLDEFSNPRKAGIIAVDLDEGDHLIGAALTDGQHDVMLFSDGGKAVRFAEDEVRPLSRTARGVRGMALE--
DGVIAMLVAEDTQSVLTATENGYGKRTSIVEYTRHGRGTKGMIAIQQSE-RNGKVVAATLVRQPDEIMLITDKGVLVRTRVSEIRELGRATQGVTLIALD
NGKLSGLQRIV-
>tr|A0A0F3NRZ1|A0A0F3NRZ1_9RICK DNA gyrase subunit A OS=Candidatus Neoehrlichia lotoris str. RAC413 GN=gyrA PE=3 SV=1
SEDLIPKEDMVVTVTMNGYIKRVKLSHYRAQKRGGKGRLGQAIKEEDITANLFIVDTHTSVLFFSNIGRVYKLKVYKLPLGEPTSRGRSLVNIFPLNENE
IITSVMPLP---NMLNIVFATSSGNVRRNALSDFQYVPSNGKIAMVLNK-DKLISVK-KEQ-DHILLSSKFGKSIRFAN--IRQKGRMSDGVRAIRLAK-
-DVISMSILIGEQFVLTVTENGFGKRTSAYEYRMALRGGAGVANIL---TRNGNVVASFPVD-KDQVMLITDKGKLIRIAVS-IRIIGRSTQGVTLFKTE
-G-VVSVAKII-
>tr|A0A0F9RRS0|A0A0F9RRS0_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_0939750 PE=3 SV=1
PEDLIKKEEVVITATNKGYIKYTLLQAYRRQGRGGKGASGMII-KEDFVEDLLIANTHSTLLFFTNLGKVHWTRVYDIPQKKRSAKGRALVNFLSLGENE
RVTTTVSID---ANRSFLMVTKKGIVKKTLLSAYSRPQKGGIIGINLRKEDKLIKVL-VEENQDAVLSTKQGKAIHFSE--IRPTGRASIGVKGISLN--
-DIRDAVIAEKNLSLLTITSKGYGKRTLFKKYRKTKRGGKGVINI--AH--KGAVVGAKKVSEDDEILVITKKGKSIRLAVRGVSLMGRATSGLRLIRLE
-DEVIALT----
>tr|A0A0G0P9A9|A0A0G0P9A9_9BACT DNA gyrase subunit A OS=Microgenomates (Woesebacteria) bacterium GW2011_GWB1_38_8 GN=gyrA PE=3 SV=1
EEDLIAKEETLIMITKTGYVKRVPRTTYRSQRRGG-G--TMT--ED-EIEQMISATTHDTILFFTNTGKVFGTKAWEIPES-RQSKGQAVVNII-NDN-E
K--SILATS--G--NHLIMATAFGVVKKTKVDQFAN-R-SGLIAIKLD--DSLVT---TD---NVLLVSKKGKSI------VRHMGRATSGMRGIKLD--
-PVIAMETFSGFRDILTISEHGLGKRTPI-LFP-QKRAGKGVKAS---NEKTGKA-VATMVT--DQIVLTSKTGQVIKLPN-NIPQ-GR---GVILMRFT
K-GVAAVAALN-
>tr|A0A0G0NHH9|A0A0G0NHH9_9BACT DNA gyrase subunit A OS=Microgenomates bacterium GW2011_GWF1_38_5 GN=gyrA PE=3 SV=1
EEDLIPKEETLITITKTGYIKRVPRTTYKAQRRGG-G--VMT--ED-EILHLVSASTHDTLLFFTNKGKVYGTKVWDIGES-RQAKGQAIVNIL-NEG-E
E--SILPMS--G--KNLIISTARGIVKKTEISEFKN-R-SGIIAIRLD--DSLVS---TD---HVLLITKKGKSI------TRAMGRATSGMRGIRLE--
-KVLGMEMFPAFRDLLTISEKGLGKRTPL-LFP-QKRSGKGVKAA---NAKTGNA-AEVIVN--EQIVVTSKFGQVIKLPV-NIPQ-GR---GVILMRFT
K-GVAAMATLE-
>tr|A0A0G0RE90|A0A0G0RE90_9BACT DNA gyrase subunit A OS=Microgenomates (Woesebacteria) bacterium GW2011_GWA1_39_21 GN=gyrA PE=3 SV=1
EEDLIPKEETLVTITKTGYIKRVPRSTYKAQRRGG-G--VMT--ED-EISHLVSASTHDTLLFFTNKGKVYGTKVWDVQES-RQAKGQAIVNIL-NEG-E
E--SFLPTS--G--KNLVIASAKGIVKKTEVAEFKN-R-SGIIAIRLD--DSVVT---TD---HILLITKKGKSI------TRAMGRATSGMRGIRLD--
-QVIGMEIFPEFRDLLTVSENGLGKRTPL-LFP-QKRAGKGVKAA---NTKTGDT-GEVIVN--EQIIITSKFGQVIKLPI-NIPQ-GR---GVILMRFS
K-GVAAIATLA-
>tr|A0A0G0MF75|A0A0G0MF75_9BACT DNA gyrase subunit A OS=Microgenomates (Woesebacteria) bacterium GW2011_GWB1_39_12 GN=gyrA PE=3 SV=1
EEDLIAKEETLITITKTGYIKRVPRATYRTQRRGG-G--TMT--ED-EIEHLISATTHDTILFFTNTGKVFGTKAWEIPES-RQAKGQAIVNIL-AGE-E
K--SILPLS--S--AHLLMATSLGIVKKTKTSEFAN-R-SGLIAIKLD--DSLVK---TD---HVLLVSKNGKGI------VRSMGRATSGMRGIKLEG-
PELIGMEIFPGFKNILIVSENGLGKRVPV-LFP-QKRAGKGVKAG---NAKTGTT-TATMVT--DQIVITSKTGQVIKLPL-NIPQ-GR---GVILMRFA
R-GVAAVAPLN-
>tr|A0A0G1CUB2|A0A0G1CUB2_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWC1_43_11b GN=gyrA PE=3 SV=1
EEDLIAKEETLITLTKTGYVKRVARGTYRSQRRGG-G--TMT--ED-EIEQIVAATTHDTLLFFTNTGKVYGTKVWEIPES-RQAKGQAIVNIL-DGE-E
K--SILPLG--S--AHLLMATSLGIVKKTRTSEFIN-R-SGLIAIKLD--DSLVK---TD---HVLLITKNGKGI------TRAMGRATSGMRGIKLD--
-SVIGMEIFPGFRDILTISEHGLGKRTPT-LFP-QKRAGKGVKAS---NAKTGKT-AATMVT--DQIIITSKTGQVIKLPN-NIPQ-GR---GVILMRFA
K-GVAAVAPLN-
>tr|U5N9U3|U5N9U3_9BURK DNA gyrase subunit A OS=Candidatus Symbiobacter mobilis CR GN=gyrA PE=3 SV=1
TEDLITPTDMVVTLSHTGYIKSQPLAEYRSQRRGGRGQATT-TKEDDWIDQLFIANTHDYILCFSNRGRLYWIKVWEVPQGSRGSRGRPIVNMFPLQ-GE
KITVVLPLTNF--DRYVFMATSMGTVKKTALDEFRNPRKAGIIAVDLDEGDYLIGAALTDGNHDVMLFSDGGKAVRFDEGDVRPLGRTARGVRGMMLE--
EGVIAMLVAEDNQSVLTATQNGYGKRTNIAEYTRHGRGTKGMIAIQQSD-RNGKVVAATLVHPGDEIMLMTDRGVVVRTRVNEIPELGRATQGVTLIGLD
EGQLIGLERIA-
>tr|W1W4J8|W1W4J8_9STAP DNA gyrase subunit A OS=Staphylococcus sp. DORA_6_22 GN=gyrA PE=3 SV=1
DEDLIPEEQIVITLSHNNYIKRLPVSTYRSQNRGGRGIQGMNT-DEDFVSQLVTMSTHDHVLFFTNKGRVYKLKGYEVPELSRQSKGIPIINAIELEN-E
TISTMIAVK---EEDYLVFATKQGIVKRSSLSNFSR-NKNGKIAINFKEDDELIAVR-TTG-EDILIGTAHASLIRFSE--LRPLGRTAAGVKGISLR--
-GVVGLDVADSEDEVLVVTENGYGKRTPVSEYRLSNRGGKGIKTATIT-E-NGNIVCITTVTE-EDLMVVTNAGVIIRLDVHDISQNGRAAQGVRLMKLG
G-FVSTVAKVN-
>tr|S5R407|S5R407_9PROT DNA gyrase subunit A OS=Candidatus Profftella armatura GN=gyrA PE=3 SV=1
TEDLIASQDMVITLSNLGYIKSQPISEYRAQKRGGRGKAMM-T-DEDWINQLFIANTHDYILCFSNYGRLYWLKVWQIPQGSRNSRGKPIINMFSLKNKE
KITVILPLS---KNNYVFMSTSLGIVKKTLLSNFSNPRKSGIIAVNLSNEDFLIGAALTDGSYD-MLFSDSGKAVRFNENSVRAMGRSARGVIGMRLEKK
--VIALLVSNNKQSVLTATENGYGKRTLIKEYTKHNRGTKGIISI--NK-RNGKVVAATLVN-YHEIMLITTGGILIRTRVSEIRKMGRSTQGVILITVE
-KKLCGVQRVM-
>tr|H5T9S6|H5T9S6_9ALTE DNA gyrase subunit A OS=Glaciecola punicea DSM 14233 = ACAM 611 GN=gyrA PE=3 SV=1
IEDLIEREEVVVTLSHEGYVKYQKLSDYEAQRRGGKGSAT-KMKDQDFIEKLLVANTHDHILCFSTRGRLYWLKVYQLPLASRNARGRPIVNILPLE-NE
RITAIL--P--EAGKYVFMATANGSVKKTELIHYSR-RANGIIAVNLNDGDELIGVDLTDGTCEIMLFSNAGKVVRFSEDQVRPMGRTATGVRGIRIA--
-TVVSLIIPNADGDILTATQNGYGKCTAVSEYPAKNRATKGVVSI--SE-RNGQVVGAVQVS-TDEIMLISDRGTLVRTRVSEVSRVGRNTQGVTLIRTV
-GHVVGLQRID-
>tr|K6YZI4|K6YZI4_9ALTE DNA gyrase subunit A OS=Glaciecola pallidula DSM 14239 = ACAM 615 GN=gyrA PE=3 SV=1
IEDLIEREDVVVTLSREGYVKYQKLSDYEAQRRGGKGSAT-KMKGEDFIEKLLVANTHDHILCFSTRGRLYWLKVYQLPLASRNARGRPIVNILPLE-GE
RITAIL--P--EAGKYVFMATTNGTVKKTELTQYSR-RANGIIAVNLNDGNELIGVDLTDGQSEIMLFSDAGKVVRFSEEQVRPMGRTATGVRGIRLM--
-NVVSLIVPQGEGDILTATENGFGKRTPIEQYPAKSRATKGVVSI--SE-RNGLVVGAIQVD-SKEIMLISDKGTLVRTRASEVSTVGRNTQGVRLIRTA
-DLVVALQRID-
>tr|W8X310|W8X310_CASDE DNA gyrase subunit A OS=Castellaniella defragrans 65Phen GN=gyrA PE=3 SV=1
TEDLITPMDMVVTLSRSGYIKSQPLSEYRAQKRGGRGQATA-TKEDDWIDQLFIANTHDYLLCFSDRGRVYWLKVWEVPQGSRNSRGRPIVNMFPLV-GE
TITVVLSVKAF--DHYVFMATSRGTVKKTPLSDFSNPRKAGIIAVGLDEGDFLIGAELTDGQHDVMLFSDAGKAVRFDENDVRPMGRTARGVRGMSLE--
DGVIALLVAEDTQSVLTATENGYGKRTPIVEYTRHGRGTKGMIAIQTSA-RNGKVVGAVLVQPEDEIMLITTGGVLVRTRVSEIREMGRATQGVTLINVD
ENLLSGVRRVV-
>tr|A0A095Z5I9|A0A095Z5I9_9BURK DNA gyrase subunit A OS=Oligella urethralis DNF00040 GN=gyrA PE=3 SV=1
MEDLITPTDMVVTLSQEGYIKSQPLSEYRSQRRGGRGQATS-MKEDDVIDSLFIANTHDYLLCFSNHGRMYWLKVYAVPQGGRNSRGRPIVNLFPLA-GE
RINVVLPVKEF--DQYVFMATSKGTVKKTPLTDFSNPRRGGIIAVNLDEGDFLIGAELTDGKHDVMLFSDDGKAVRFDESDVRPMGRNARGVRGMNLD--
DEVIALLVADDGRSVLTATENGFGKRTSITEYPRHRRGNKGVIAIQTSE-RNGKVVGAVLVEEADEIMLITSAGVLVRTTVEQIREMGRATQGVTLINCD
EGFLTGVKRVV-
>tr|H3NRC3|H3NRC3_9GAMM DNA gyrase subunit A OS=gamma proteobacterium HIMB55 GN=gyrA PE=3 SV=1
VEDLITEEDRVVTISHQGYAKTQSLTDYQAQRRGGTGSATA-VKDEDFVEHLLIASTHATVLCFSNMGKVYWLKVFHIPLASRNARGRPMVNLLP-LDNE
RITSILPIEGYDEDQFIFMATANGTVKKTAATQFARQRSVGLRAIELDEDDVLVGTAITDGNSDIMLFSSEGKATRFNESQVRAMGRTARGVRGINLADH
K-LISLIVPKEGGRILTVTENGYGKRTENAEFPAKGRGGKGVIAMSTSA-RNGSLVGAVQVWDTDEMMLISNQGTAVRTRVEEVSLLGRNTQGVRVIRTR
DGALVSVSRIV-
>tr|B8KX24|B8KX24_9GAMM DNA gyrase subunit A OS=Luminiphilus syltensis NOR5-1B GN=gyrA PE=3 SV=1
VEDLITEEDRVVTISHGGYAKTQPLTDYQAQRRGGTGSATA-VKDEDFVEHLLIASTHSTILCFSNLGKVYWLRVFNIPVASRNSRGRPMVNLLPLD-GE
RVTSILPVEGYEAGSYIFMATAKGTVKKTEMTQFARQRSVGLRAIELEEGDHLVGTAVTDGSCDVMLFSSEGKAVRFNEAAVRPMGRTAKGVRGIRLGGY
S-LISLIIPK-QGRILTVSENGYGKRSETADFPVRGRGTMGVIAMSTSD-RNGALVGAEQVWDGDEIMLISNQGTAVRTRIDEISLQGRNTQGVRVIRTR
DESLVSISRIA-
>tr|F3LEX0|F3LEX0_9GAMM DNA gyrase subunit A OS=gamma proteobacterium IMCC1989 GN=gyrA PE=3 SV=1
IEDLITEEDRVVTISHGGYAKTQALSDYQAQRRGGTGAATS-VKDEDFVEHLLIASTHDTILCFTNAGKVYWLKVFQIPLAGRQSRGRPIINLLP-LDSE
RITSILPVREYDEDHFIFMATANGTVKKTPLTQFARPRTSGLRAIDLEEDNHLVGTAVTDGNSDVMLFSSEGKAVRFNENDVRSMGRTSRGVRGIRLAEY
E-VISMVLPT-DGKVLTVSENGYGKRTKVDEYATKGRAGKGMIAMQTSE-RNGKVVGAVQVFDGDEIMLISDQGTMVRTHVDEVSVSGRNTQGVRVIKVK
DGHLMGVERIE-
>tr|A0Z754|A0Z754_9GAMM DNA gyrase subunit A OS=marine gamma proteobacterium HTCC2080 GN=gyrA PE=3 SV=1
VEDLITEEDRVVTISHGGYAKTQSLSDYQAQRRGGTGSATA-VKDEDFVEHLLIASTHATILCFSDLGKVYWLKVFHIPLASRNARGRPMVNLLPLD-GE
RITSILPVEGYEEGHFIFMATARGIVKKTDMQQFARQRSVGLRALELEADDWLVGTAVTDGSCDVMLLSSEGKAVRFQEQAVRAMGRTARGVRGIKLGDH
R-LISLIVPQ-DSTILTVSEKGYGKRTDTEEFPCKGRGTKGVIAMATTA-KNGPLVGAVQVSTGDEIMLISDQGTAVRTRVEEISTLGRNTQGVRVIKTR
EDKLVRLSRIV-
>tr|A4AAR3|A4AAR3_9GAMM DNA gyrase subunit A OS=Congregibacter litoralis KT71 GN=gyrA PE=3 SV=1
AEDLITPEDRVVTLSHGGYAKTQPLAEYQVQRRGGMGAALS-VKDEDFVEHLLIANTHDTLLCFTNLGKVYWIKVYQIPVAGRSSRGRPMVNLLQ-LDGE
RVTSILPLEEHSDDRFIFMATAQGYVKKTDLASFA-PRSAGLRAIVLGEDDVLVGTAITDGNQDVMLFSSEGKATRFSESAVRAMGRASRGVRGINLADH
R-MISLLVPDARGTVLTVSENGYGKRTTVDDFPTKGRGGKGVIAMASSE-RNGRLVGALQVFSGDELMLISNQGTLVRTQCDQVSQLGRNTQGVRIIRTK
EGTLVRVERIV-
>tr|U7PGK6|U7PGK6_STASI DNA gyrase subunit A OS=Staphylococcus simulans UMC-CNS-990 GN=gyrA PE=3 SV=1
DEDLIPEEQIVITLSHNNYIKRLPVSTYRAQNRGGRGVQGMNT-EEDFVSQIVTLSTHDHVLFFTNQGRVYKLKGYEVPELSRQSKGIPVINAIELEN-E
VISTMIAVK---EDAFLIFATKHGIVKRSSLSNFSH-NRNGKIAINFRDEDELVAVR-TDG-KDVLLGTSRASLIRFKE--LRPLGRTAAGVKGITLR--
-GVIGLAVANGEDEVLVVTENGYGKRTPLEEYRVSNRGGKGIKTATIT-E-NGDIVCITTVTE-EDLMIVTNHGVIIRIDVGDISQNGRSAQGVRLIRLS
E-FVSTVAKVQ-
>tr|K9ALA6|K9ALA6_9STAP DNA gyrase subunit A OS=Staphylococcus massiliensis S46 GN=gyrA PE=3 SV=1
DEDLIPEEQIVITLSHNNYIKRLPVSTYRAQNRGGRGVQGMNT-EEDFVSQLVTLSTHDHILFFTNKGRVYKLKGYEVPELSRQSKGIPIVNALEIEK-E
VISTMIAVK---EDDYLVFATKQGIVKRSRLNNFSR-NKNGKIAISFKDHDELIAVR-IDG-QDILIGTKHASLIRFDE--LRPLGRTAAGVKGITLR--
-GVVGLDVAHKDDEILVVTDKGYGKRTNVNEYRLSNRGGKGIKTATLT-E-NGDIVCITTVSD-EDLMIVTNLGVIIRLQVEDISQTGRATQGVRLIRLQ
N-FVSTVAKVK-
>tr|A0A0D0RRZ5|A0A0D0RRZ5_STAGA DNA gyrase subunit A OS=Staphylococcus gallinarum GN=gyrA PE=3 SV=1
DEDLIPEEQIVITLSHNNYIKRLPVSTYRAQHRGGRGVQGMNT-EEDFVSQLVTLSTHDNVLFFTNKGRVYKLKGYEVPELSRQSKGIPVVNAIELDN-E
AISTMIAVK---EEDYLVFATRKGIVKRSALSNFSH-NKNGKIAIGFKDDDELIAVR-TDG-DDILIGTSHASLIRFPE--LRPLGRTAAGVKGITLR--
-GVVGLDVAKSNDEILVVTENGYGKRTPVNDYRLSNRGGKGIKTATIT-E-NGNIVCITTVNE-EDLMVVTNSGVIIRIDVQDISQNGRAAQGVRLIKLS
E-YVSTVAKVS-
>tr|A0A078M7I1|A0A078M7I1_9STAP DNA gyrase subunit A OS=Jeotgalicoccus sp. 13MG44_air GN=gyrA PE=3 SV=1
DEDLIPREQIVVTLSHNNYIKRLPASTYRAQHRGGRGIQGMNT-DDDFVSQIVTMSTHDYILFFTNTGRVYRLKGYEIPELSRQSKGLPIVNLIEIGK-E
KISTMISVKT--EGYHLLFATKNGLAKRTPLDDFKQ-NKNGKIAISFRGEDELLGVR-TDG-KEVILGTREGSLVRFEE--VRSMGRTAAGVKGINLR--
-DVVGVDVLDP-QHVLVVTDKGYGKLTHEKEYRSINRGGFGVKTANLT-D-NGKLVYIASVDD-EDMMIVTDKGVIIRLTIDTISITSRNTQGVRLIRLD
E-DVATVAVVK-
>tr|K9RE53|K9RE53_9CYAN DNA gyrase subunit A OS=Rivularia sp. PCC 7116 GN=gyrA PE=3 SV=1
DIDLIANEKVIILLTQQGYMKRMPVNTFEAQSRATRGKAAAKV-DDDNIEHFLTCCDHDSVLFFSERGVVYCMKAYQLPLGSRTSRGTPIVQMLPIPKEE
KITSIVPVS---QDEYLVMLTKGGYIKKTALAAFSNIRANGLIAISLEEGDELRWVRRARAEDSVIIGSRMGMAIHFRC--LRPLGRATRGVKAMKLR--
-DLVGMDVLPAGLWVLVITTGGYGKRVPVGQFRLQNRAGQGLMATKFLKT-QDQLASLHIVS-DNEIMMVTSRGIIIRQAVNAISIQSRSATGVRVQRLD
-DFLNGVAIVP-
>tr|M1X013|M1X013_9NOST DNA gyrase subunit A OS=Richelia intracellularis HH01 GN=gyrA PE=3 SV=1
DIDLIANDKAIILLTEQGYIKRMPVNTFEAQSRATRGKAAAKV-NDDTVEHFLSCCDHDSVLFFSDRGVVYCLKAYQITMGSRTSRGTPIVQMLPIPKKE
KITSIIPVN---DDEYLVMLTQGGNIKKTSLSAFSNIRANGLIAISLEKGDQLRWVRKAKAEDSIIVGSRNGMAIHFRC--LRPLGRATRGVRAMKLK--
-DLVGMDIIPAGPWVLVITNGGYGKRVPMPHFRLQNRAGQGLMVTKFSKT-KDKLASLQIVK-EDEIMMVTNRGIIIRQAVNAISIQSRSATGVKVQRLD
-DAITGVAIVP-
>tr|M5B742|M5B742_9MICO DNA gyrase subunit A OS=Clavibacter michiganensis subsp. nebraskensis NCPPB 2581 GN=gyrA PE=3 SV=1
MEDLIPEEEMVVTVTRGGYIKRTRIDNYRSQHRGGKGVRGA-QRADDVVEHFFVTTTHHWLLFLTDKGRVYRAKAYELQEAGRDAKGQHVANLLAMQPDE
EIQQVLDIR---AQ-YLVLATRDGLMKKTALTEYDT-RTGGIIAINLRDGDALVSAL--DEDDDLLLVSRKGMSLRFSQ--LRPMGRSTSGVKGMTFR-D
-DLLSASV-VGQGYVFVVTEGGFAKRTAADQYRVQNRGGMGIKVAKLQ-D-RGDLAGALIVGE-DEILVVLASGKVVRSVVAEVPA-GRDTMGVVFARFA
-DRIISLAKNS-
>tr|A0A099NMH9|A0A099NMH9_9BURK DNA gyrase subunit A OS=Taylorella equigenitalis GN=gyrA PE=3 SV=1
TEDLITPMDMVVTLSNEGYIKSQPLSEYQAQNRGGKGKATE-MKDNDFVQQLFIANTHDYVLCFSSLGRLHRLKVWEVPQGGRNSKGRPIVNLFELQ-NE
KITVVLPIKQF--DQFIFLATAKGVVKKTALSQYSSTRKMAVIAVTLDEDDYLVGAELTDGNSDIMLFSNAGKAVRFDESSVRATGRSSRGVLGMRLE--
EGIISLIVSKNNAYVLTATENGYGKRTPVVEYTRHGRGTKGMIAIQTSE-RNGKVVAAVLVDESDEIMLITTDGIVVRTKVAPIRELGRATQGVKLIRID
NDKLKGVQRVV-
>tr|I7IKH8|I7IKH8_9BURK DNA gyrase subunit A OS=Taylorella asinigenitalis 14/45 GN=gyrA PE=3 SV=1
TEDLITPMDMVVTLSKEGYIKSQPLSEYQAQNRGGRGKATE-MKDDDYIQQLFIANTHDYVLCFSSLGRLHRLKVWEVPQGTRTSKGKPIVNLFDLQ-NE
RITVVLPIKQF--DQFIFLATAKGIVKKTALSQYSSTRKMAVIAVTLDDDDYLVGAELTDGNSDIMLFSDAGKAVRFDESSVRATGRSSRGVLGMRLE--
EGIISLIVSKDQASVLTATENGYGKRTAVTDYTRHGRGTKGMIAIQTSD-RNGKVVAAVLVHPEDEIMLITTDGIVVRTKVEQIREMGRATQGVTLIRVD
QGKLSGVQRVV-
>tr|A0A0R1TDH1|A0A0R1TDH1_9LACO DNA gyrase, A subunit OS=Lactobacillus paracollinoides DSM 15502 = JCM 11969 GN=FC17_GL000453 PE=4 SV=1
DEDLIEEENVMVSLTHNGYIKRLPTTEFKAQNRGGRGIQGMGI-DDDFIEHLISTSTHDVLLFFTNAGKVYRMKGYEIPEYGRSAKGIPIINLLNV-DKE
SIQAVINVS--DQEKYLFFTTLKGTVKRTPVDEFSN-RSNGLKALNLKDDDELINVS-VDA-QNMIIGTHSGYAVSFQA--VRSMGRSATGVRGVRLR--
-DVVGSAILGPTSNVFVISEKGYGKQTPADEYAIKGRGGKGIKTINIT-E-NGPLAGLTSVNE-EDIMLITDKGVMIRFGVENVSQTGRATLGVHLIRLD
D-KVATMAVVE-
>tr|A0A0R1HQ24|A0A0R1HQ24_9LACO DNA gyrase, A subunit OS=Lactobacillus kimchicus JCM 15530 GN=FC96_GL001638 PE=4 SV=1
DEDLIEEEDVIVSLTHNGYIKRLPTTEFKAQNRGGRGIQGMGI-DDDFIEHLISTSTHDVMLFFTNTGKVYRMKGYEIPEYGRSAKGIPVINLLNI-NDE
HVESVINVS--EQNRYLFFTTLHGTVKRTPVEEFSN-RSNGLKAISLKEGDEVMNVS-VDD-QNMIIGTHRGYAASFQT--VRSMGRSATGVRGIRLR--
-DVVGAAVLAPNSNVFVISEKGYGKQTPASEYAIKGRGGKGIKTINVT-E-NGPLAGLTTVTE-EDIMLITDKGVMIRFGVENVSETGRATLGVHLIRLD
E-TVATMAVVE-
>tr|A0A0N0L0M1|A0A0N0L0M1_9MICO DNA gyrase subunit A OS=Frigoribacterium sp. RIT-PI-h GN=gyrA PE=3 SV=1
VEDLIPEEEMVVTITRGGYVKRTRSDNYRSQHRGGKGVRGA-QRADDVVDHFFVTTTHHWLLFLTNKGRVYRAKTYELQEAGRDAKGQHVANLLAMQPDE
QISQVLDIR---AD-YLVLATRDGLIKKTALTEYDT-RTGGIIAINLRDDDELVSAL--DEHDDLLLVSRHGMSLRFTE--LRPMGRSTSGVKGMTFR-D
-DLLSASV-VGEGYVFVVTEGGYAKRTAADQYRVQNRGGLGIKVAKLA-E-RGDLAGALIVGD-DEVLVVLSGGKVVRSAVSEVPA-GRDTMGVVFARFA
-DRIIAVARNS-
>tr|A0A0C5BIX8|A0A0C5BIX8_9MICO DNA gyrase subunit A OS=Rathayibacter toxicus GN=gyrA PE=3 SV=1
VEDLIPEEEMVVTVTRGGYLKRTRSDSYRAQHRGGRGVRGA-QKADDIVEHFFVTTTHHWLLFFTNTGRVYRAKTYELQEAGRDAKGQHIANLLALEPGE
QIAQILDIR---AR-YLVLATRDGLVKKTALAEYDT-RSGGIIAIKLREGDELMSAL--EDDSDVLLVSRKGMSIRFTQ--LRPMGRSTSGVIGMSFR-D
-DLLDANVVN-EGSVFVVTEGGYAKRTGVSHYRLQGRGGLGIKVAKLE-E-RGDLVGAIITRD-DEVLVVLASGKVVRSAVAEVPA-GRDTMGVVFARFA
-DRIIALAKNT-
>tr|A0A0Q9T7F9|A0A0Q9T7F9_9MICO DNA gyrase subunit A OS=Yonghaparkia sp. Soil809 GN=ASG83_04815 PE=4 SV=1
VEDLIPEEEMVVTVTRGGYIKRTRSDNYRSQHRGGKGVKGA-QRADDVVEHFFVTTTHHWLLFFTTTGRVYRLKTYEIQEAGRDAKGQHVANLLALQPGE
EIAQILDIR---AK-FLVLATRNGLVKKTALTEYDT-RSGGIIAINLRDGDELVSAM--EEESDILLISRGGMSVRFTS--LRPMGRSTSGVRGMSFR-D
-DLLSASV-VHDGYVFVVTEGGYAKRTAVDQYRVQGRGGLGIKVAKLN-D-RGGLAGGIIVAD-DEVLVVLAGGKVVRSAVSEVPA-GRDTMGVVFARPD
-DRIIAIARNS-
>tr|A0A094PEP6|A0A094PEP6_9ACTN DNA gyrase subunit A OS=actinobacterium acMicro-1 GN=gyrA PE=3 SV=1
LEDLIAEEEMVITVTRGGYIKRTRSDNYRSQHRGGKGVKGA-QRADDVVEHFFVTTTHHWLLFFTNTGRVLRVKAHEVMETGRDAKGQHVANLLALNPDE
EIRQILDIR---AR-FLALATKGGMIKKTALEAYDT-RTGGIIAINLRDGDELVSAL--DEDTDVLLVSRKGMSLRFTE--LRPMGRSTAGVTGMKFR-D
-DLLDAAVVT-ESFVFVATEKGYAKKTATSQYRTQNRGGLGIKVAKLS-E-RGDLAGAIIVEE-DEVLVVLESGKVVRSPSTEVPA-GRDTMGVVFTRFD
-TRILAIAKNS-
>tr|A0A0Q5K364|A0A0Q5K364_9MICO DNA gyrase subunit A OS=Curtobacterium sp. Leaf154 GN=ASF75_14960 PE=4 SV=1
MEDLIPEEEMVVTITRGGYVKRTRSDQYRSQHRGGRGVRGA-QRADDIVEHFFVTTTHHWLLFLTDQGRVYRAKAYELQEAGRDAKGQHVANLLAMQPDE
QIQQVLDIR---AQ-YLVLATEHGLVKKTALTEYDT-RTGGIIAINLRDGDKLRQAL--DEHDDLLLVSRQGMSLRFTD--LRPMGRSTSGVKGMSFR-G
-DLLAARV-VSDGFVWVMTEGGYAKRTAVDQYRVQGRGGLGIKVAKLA-L-RGDLVGALIVGD-DEVLVVLQSGKVVRSAVAEVPA-GRDTMGVVFARFA
-NRIIAVARNT-
>tr|K9PCW1|K9PCW1_CYAGP DNA gyrase subunit A OS=Cyanobium gracile (strain ATCC 27147 / PCC 6307) GN=gyrA PE=3 SV=1
DIDLIANERSVVLLTENGYLKRMPVSEFEATSRGTRGKAGTRS-GEEAVKLFISCNDHDALLLFSDRGVVYSIPAYRVPICSRSAKGTPIVQLLPIPREE
AITSLLAVS---DDVQLVMLTSGGYIKRTRLSAFSNIRSNGLIAISLEDGDALRWVRLALPGDSVLIGSLKGMTIHFRL--LRPLGRSARGVRAMNLR--
-DLVSMDVLTAGPWVLVASASGLGKRVPVDQFRLQRRAGMGLRAIKF--D-GDVLVGLKVLG-GEELLLVSERGVIVRMKADAIPQQSRAATGVRLQKLD
-GRLTEVVLVP-
>tr|A5GRY6|A5GRY6_SYNR3 DNA gyrase subunit A OS=Synechococcus sp. (strain RCC307) GN=gyrA PE=3 SV=1
DIDLIANERSVVLLTENGYLKRMPVSEFESTSRGTRGKAGTKS-GEEAVRLFISCNDHDSLLLFSDRGVVYSLPAYRVPIASRAAKGTPVVQLLPIPREE
QITSLLAVS---EDVQLVMLTTGGFIKRTPLSAFSNIRANGLIAINLEDADSLRWVRLARAGDSVLIGSINGMTIHFRI--LRPLGRTARGVRAMALR--
-DLVSMDVLPAGPWVLVATASGLGKRVPVDQFRLQRRAGLGLRGIKF--D-GDALVGLCVMG-EEELLLVSERGVIVRLQSDVIPQQSRAATGVRLQRLD
-GRLAEVVLVP-
>tr|B1X5H0|B1X5H0_PAUCH DNA gyrase subunit A OS=Paulinella chromatophora GN=gyrA PE=3 SV=1
DIDLIANERSVVLLTENGYLKRMPVSEFEATNRGTRGKAGTKN-GDEGVKLFISCNDHDTLLLFSDRGISYALPAYRVPVSSRSAKGTPVVQILPIPREE
EITSLLSVS---NEVQLLMLTNSGFIKRTRLSAFSNIRSNGLIAINLELGDALRWVRLALPGDSVLIGSIQGMTIHFRI--LRPLGRNARGVRAMNLR--
-DLVSMDVLPAGPWVLVASASGLGKRVPVNQFRLQRRAGMGLRAMRF--K-GDVLVGLKVLG-REELLLVSEKGVIVRMQADLIPQQSRAATGVRLQKLD
-GHLAEIVLIP-
>tr|A0A0R2U956|A0A0R2U956_9CYAN DNA gyrase subunit A OS=cyanobacterium BACL30 MAG-120619-bin27 GN=ABR96_02570 PE=4 SV=1
DIDLIANERSVVLLTENGYLKRMPVSEFEATSRGTRGKAGTKT-GEEAVRLFISCNDHDNLLLFSDRGVVYTVPAYRVPISSRAAKGTPIVQMLPIPREE
QITSLLAVS---DDGVLVMLTSGGTIKRTRLSAFANIRSNGLIAIDLVEGDALTWVRLALPGDSILIGSRNGMTIHFRL--LRPLGRTARGVRAMNLR--
-DLVSMDVLPAGPWVLVASASGLGKRVPVDQFRLQKRAGMGLRAIKF--K-SDVLVGLKVLG-GEELLLVSEKGVIVRTQADAVPQQSRAATGVRLQKLD
-RRLSEVVLVP-
>tr|A0A0E3URG2|A0A0E3URG2_9PROT DNA gyrase subunit A OS=Arcobacter lanthierii GN=gyrA PE=3 SV=1
IEDLIPNEPMVVTITHNGYVKRVPIKSYEKQKRGGKGVAVT-T-DDDFIERFFVSNTHDTLMFVTNMGQLYWLKVYRIPEGSRIAKGKAVVNLINLRPDE
KIMAIIPTS---EAKSLAFFTKNGVVKRTALNEFSNIRSNGVRAIVLDDDDEIVTAQ----SKYFMIFTALGQVIRFFKRGVKPQGRTTRGVRGIKFKD-
-DVVDADVIESEQEILTVSEKGIGKRTTVEEYRLTNRAGSGVIAMKLS--KTGN-VVGEVVD-TQDLMLLTSIGKMIRVDMNTIRKAGRNTSGVIIVNVD
--KVVSIAKCP-
>tr|A1BPQ8|A1BPQ8_9PROT DNA topoisomerase (ATP-hydrolyzing) (Fragment) OS=Arcobacter nitrofigilis PE=3 SV=1
IEDLIPNEPMVVTITHNGYVKRVPIKSYEKQRRGGKGVAVT-T-DDDFIERFFVTNTHDTLMFVTNMGQLYWLKVYRIPEGSRTAKGKAVVNLINLRPDE
KIMEIIPTS---ESKSLAFFTRNGVVKRTSLSEFSNIRSNGVRAIVLDDADEIVTAK----TQYLMIFTSLGQCIRFD---TREQGRSTRGVRGIKFKD-
-DVVDANVVDNEQELLTVSQKGIGKRTTVEEYRETNRAGSGVISMKLS--KTGN-VVGAVVD-AQDLMILTSIGKMIRVDMQTIRKAGRNTSGVIIVNVD
--KVVSIAKCP-
>tr|A0A0N1B8L7|A0A0N1B8L7_9PROT DNA gyrase subunit A OS=alpha proteobacterium AAP81b GN=gyrA PE=3 SV=1
DEDLIEREDMVVTVTLDGWIKRVPLAEYRVQARGGKGKSAMATKDEDVVTTLFVTSTHNPVLFFSSAGKVYRKKVWRLPLGSRQAKGRSLNNLLPL-AGE
TITTVLPLP---GRLNVMFATAKGGVRRNAMDAFTNVPTAGKLAIRFEDNDRLIGVA-EAD-EDVFLAAKSGKAIRFPD--VREVSRTSTGVRGMTLD--
-DVVSMAVLKREEFILTVTANGFGKRSSAFEYRRSGRGGQGVRNIA---SRNGDVVASFPAH-GDGLILVTDQAKLIRMSVA-IRIMGRAAQGVTLFKVN
-G-VVSAALVP-
>tr|J0UX33|J0UX33_ALCFA DNA gyrase subunit A OS=Alcaligenes faecalis subsp. faecalis NCIB 8687 GN=gyrA PE=3 SV=1
TEDLITPMDMVVTLSHTGYIKSQPLSEYRAQRRGGRGQATA-MKEDDWIDKLFIANTHDYLLCFSNRGRVYWLKVWEVPQGSRNSRGRPIVNMFPLE-GE
KINVVLSVKEF--DQFVFMATSRGTVKKTPLSDFSNPRKAGIIAVGLDEGDYLIGAQLTDGVHDVMLFSDAGKAVRFDEGDVRPMGRAARGVRGMTLE--
EGVIALLVAEDTQSVLTATQNGFGKRTPIGEYTRHGRGTKGMIAIQTSA-RNGKVVGAVLVRETDEIMLITNAGVLVRTRVAEIREMGRATQGVTLISVD
DDELSGVYRVV-
>tr|A0A0F6ADX6|A0A0F6ADX6_9GAMM DNA gyrase subunit A OS=Pseudoalteromonas luteoviolacea S4054 GN=gyrA PE=3 SV=1
LEDLINEEDVVVTLSHEGYVKYQPLSDYEAQRRGGKGAAT-RMKDEDFIERLLVANTHDTILCFSTAGRLYWLKVYQLPLASRQARGKPIVNLLPLE-DE
RITTIL--P--EEDKYVLMATANGTVKKTPLTAYSR-RASGIIAINLNEGDNLIGADITDGSNDIMLFTDHGKVVRFNEKALRPMGRTATGVRGIKMP--
-GVVSLIVPKNDGAILTVTENGYGKRTPLDEYPAKSRATQGVVSI--TE-RNGNVVGAVQVE-NNEIMLISNRGTLVRTRVNEVSTVGRNTQGVILIRTI
-DQVVGLQRIE-
>tr|L8D7E8|L8D7E8_9GAMM DNA gyrase subunit A OS=Pseudoalteromonas luteoviolacea B = ATCC 29581 GN=gyrA PE=3 SV=1
LEDLINEEDVVVTLSHEGYVKYQPLSDYESQRRGGKGAAT-RMKDEDFIERLLVANTHDTILCFSTAGRLYWLKVYQLPLASRTARGKPIVNLLPLE-DE
RITAIL--P--QEDKYVIMATADGTVKKTSLIEYSR-RSSGIIAINLKEGDSLIGVDITDGSSEIMLFSDAGKVVRFKEGGVRPMGRTATGVRGIKLA--
-DVVSLIVPKNDGAVLTVTENGYGKRTPLEEYPVKGRATQGVVSI--SE-RNGKVVGAVQVQ-NDEIMLISNRGTLVRTRVNEVSVVGRNTQGVILIRTI
-GQVVGLQRID-
>tr|A0A0M3ARP3|A0A0M3ARP3_9SPHN DNA gyrase subunit A OS=Sphingobium chungbukense GN=gyrA PE=3 SV=1
DEDLIEREEMVVTVTVQGYIKRTPLESFRAQARGGKGRSGMATKDEDAVTELFVTSTHTPVLFFSTAGKVYRLKVWRLPEGGPATRGRPMVNLLPL-SGE
TIQTVLPLP---KDLHVMFATANGTVRRNSMDAFANIPSNGKIAMRFDDTDRLIGVA-TEE-DDVLLATRQGKAIRFQD--VREQSRTSTGVRGMTLK--
-DVISLSVLHREQFILTVCANGYGKLSSAYDYRRTGRGGQGITNID---IRNGPVVASFPAT-ADQLMLVTDQAKLIRMGLD-LRVIGRSSAGVRLFNVS
-D-VVSAAKIE-
>tr|A0A031GFL3|A0A031GFL3_MICLU DNA gyrase subunit A OS=Micrococcus luteus GN=gyrA PE=3 SV=1
IEDLIPEEEMVVSITRGGYVKRTRIDQYRSQARGGKGVRGA-MRGDDVVEHFLTVSTHHWLLFFTNFGRVYRIKTYELLEAGRDAKGQHVANLLAFQPDE
RIAQIQPLV---AP-YLVLATRGGLVKKTPLLDYDT-RTAGLIAIKLREGDELVSAR--SPDDDLILISHKGQSLRFTE--LRPMGRATSGVTGMKFR-D
-DLLTMDVVEEDGYVFTVTDGGFAKRTHVDEYRLQNRGGLGIKVAKLV-D-RGELAGGLVVRD-QEVLVVMASGKVVRSAVAGVPA-GRDTMGVIFAKPD
-RRIVAVTLNN-
>tr|A0A0D1PPZ4|A0A0D1PPZ4_9BRAD DNA gyrase subunit A OS=Bradyrhizobium sp. UASWS1016 GN=gyrA PE=3 SV=1
IEDLIPEEEVVVTITRSGYVKRTKVDNYRAQNRGGKGVRGA-ARDEDVVEHFFTTSTHNWLLFFTNFGRVYRIKGYELQEAGRDARGQHVANLLAFQPDE
HIAQVLTLE---AP-YLVLATKSGMVKKSRLEDYDS-RQAGLIAINLNE-DEVVAAK--DETDDLILISRKGQSLRFTE--LRPMGRATAGVRGMKFR--
-DLLTMAVIED-AYVFTITDGGFAKRTSVDEYRTQNRGGYGIKVANLP-E-RGELVGGEVVKD-TEVLVIMESGNVVRSAVEQVPI-GRDTMGVIFASPG
-NRIVGATLNY-
>tr|A0A0K1NCX3|A0A0K1NCX3_9BURK DNA gyrase subunit A OS=Ottowia sp. oral taxon 894 GN=gyrA PE=3 SV=1
TEDLITPTDMVVTLSHTGYIKSQPLNEYRAQKRGGRGQATT-TKEDDWIDQIFIANTHDYILCFSNRGKLYWLKVWEAPSGSRGSRGRPIVNMFPLE-GE
KITVVLPLTAF--DRYVFMATAGGTVKKTALNEFSNPRKAGIIAVGLDEGDYLIGAALTDGKHDVMLFSDGGKAVRFDENDVRHMGRQARGVRGMNLE--
EGVIAMLVAEARNSVLTATENGYGKRTHISEYTRHGRGTKGMIAIQQSE-RNGKVVAATLVNADDEIMLITDKGVLVRTRVAEIREMGRATQGVTLIALD
DGRLSGLQRIV-
>tr|A0A0F6SFC1|A0A0F6SFC1_9DELT DNA gyrase subunit A OS=Sandaracinus amylolyticus GN=gyrA PE=3 SV=1
IEDLIANEPMAVTVTHGGYLKRVPLTEYRAQGRGGKGTRAAEL-EEDFVAQLFVANAHADLLFLSDKGKAYAKKVYEIPVASRASRGRHVNNMLAVDPGE
RIAAIVP---FEE-HFLLTCTRGGTVKRTALSAYANMRSSGIIGVQIEDGDQLLAAR-VDVKSEVLIGTAKGMSIRFQV--VRPMGRDTRGVRGIDLR--
-DVIGMDVIDDSKQVLAISANGYGKRTPLKTWRMQNRGGLGIIAM--SR--NGELVALRVVSPDDQVMVITNGGQIIRTHVHQIREAGRNTQGVRIIRVS
-DRVVDVERLA-
>tr|A0A069G6L9|A0A069G6L9_STAAU DNA gyrase subunit A OS=Staphylococcus aureus subsp. aureus CO-98 GN=gyrA PE=3 SV=1
DEDLIPEEQIVITLSHNNYIKRLPVSTYRSQHRGGRGVQGMNT-EEDFVSQLVTLSTHDHVLFFTNKGRVYKLKGYEVPELSRQSKGIPVINAIELDN-E
TISTMIAVR---EDSYLVFATKNGIVKRSALSNFSH-NKNGKIAIGFKEDDELIAVR-TDG-QDILIGTSHASLIRFAE--LRPLGRTAAGVRGISLR--
-DVVGLDVAHAEDEVLVVTENGYGKRTPVSEYRLSNRGGKGIKTAKIT-E-NGNIVCITTVNE-EDLMIVTNSGVIIRLEVEDISQNGRATQGVRLMKLG
D-FVSTVAKVI-
>tr|H0DJU0|H0DJU0_9STAP DNA gyrase subunit A OS=Staphylococcus pettenkoferi VCU012 GN=gyrA PE=3 SV=1
DEDLIPEEQIVITLSHNNYIKRLPVSTYRAQHRGGRGVQGMNT-EEDFVSQLVTLSTHDHVLFFTNKGRVYKLKGYEVPELSRQSKGIPVINAIELDN-E
SISTMIAVK---EDHFLVFATKRGIVKRSALSNFSH-NKNGKIAISFKEDDELIAVR-TDG-EDILIGTAHASLIRFQE--LRPLGRNAAGVKGISLR--
-NVVGLDVAHEEDEVLVVTEKGFGKRTPVSDYRLSNRGGMGIKTATIT-E-NGNIVCITTVTD-EDIMVVTNHGVIIRMEAQDISQNGRAAQGVKLIRLG
N-HVATVAKVN-
>tr|W6TDZ6|W6TDZ6_HOLOB DNA gyrase subunit A OS=Holospora obtusa F1 GN=gyrA PE=3 SV=1
PEDLVACEDMVVTVSVNGYIKRVPLDAYRSQKRGGRGKNAMDVREEDAVCQIFVADTHRPLLFFTSKGIAYQMKVYELPLGTTSSRGKPLIAFFPLERIE
KIATILPLP------FIVFSTSQGNVRKNAVSDFFTIRANGKIAMKLDD-EQLIRVV-DDN-QDILLSTHQGKSLRFSE--LRQNSRNSTGVRGILLKK-
-DVVSMTLLMHEEFVLCVTMKGVGKRTSSYEYRRAHRGGQGVATME---TRTGAVIQAMPVK-QDQILMLTSLGQLLRCPVK-IRISGRRTQGVRVFRLD
-G-VVSVAVVS-
>tr|A0A023DXN9|A0A023DXN9_9RICK DNA gyrase subunit A OS=Holospora elegans E1 GN=gyrA PE=3 SV=1
PEDFVACEEMVVTVSVNGYIKRVPLDAYRSQKRGGRGKNAMDVREEDAVSQIFVADTHRPLLFFTSKGIVYQMKVYELPLGITSSRGKPLIAFFPLEKTE
KVATILPLP------FIIFATSHGNVRKNALSDFFSIRANGKIAMKLAE-EQLIRVL-NDD-QDILLSTHQGKSLRFPE--LRQSSRNSTGVRGIFLKG-
-DVVSMTLLNNEEFVLCVTIKGFGKRTSSYEYRRTHRGGQGVATME---TRTGSIIQAMPVK-QDQILMLTNAGQLLRCPVK-IRISGRRTQGVRVFRLD
-G-VASVAVIS-
>tr|A0A0A7RZV0|A0A0A7RZV0_9GAMM DNA gyrase subunit A OS=Frischella perrara GN=gyrA PE=3 SV=1
IEDLIAQEDVVVTLSHQGYVKYQPLSDYEAQRRGGKGSAT-KIKEEDFIEKLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIINLLPLE-NE
RITAIL--P--DDEHCVFMATSQGTVKKTSLIEFSR-RSGGIIAINLRDDDELIGVDLTLNTEDIMLFSANGKVVRFPANKVRTMGRTAAGVRGIKLE--
-GVVSLIVPRGNGAILTATQNGYGKRTEQASYPTKSRATKGVISI--SE-RNGQVVGAVQVE-SDQIMLITDAGTLVRTRVSEVSIVGRNTQGVTLIRTA
-NKVVGLERVA-
>tr|A0A0P7ZJJ0|A0A0P7ZJJ0_9CYAN DNA gyrase, A subunit OS=Phormidesmis priestleyi Ana GN=gyrA-2 PE=4 SV=1
DISLIANEQVAILVTEQGYIKRMLIDTFEAQNRATRGKSGTKM-EDDGIEHFITCCSHDHVLFFTDKGISYSLRAYQIPESSRTAKGYPLVQMLPIPKEE
KVTSVISVS---ADEYLVMLTQGGFVKKTALSAFSRIRTNGLIAISLEEGDELRWVRLARSEDSILIGSQRGMTIHFKT--LRPLGRPTKGVRAMSLR--
-DLISMDILSSGPWVLVVSAGGLGKRVPVSNFRLQNRAGMGLVAMKFD---NDELVALRIAS-DDELMIVSQRGIIMRQAIDAISIQSRMATGVQLQKLD
-DAIAAVALVP-
>tr|U1HC35|U1HC35_9ACTN DNA gyrase subunit A OS=Propionibacterium granulosum TM11 GN=gyrA PE=3 SV=1
EEDFIPDDDVVVTITRGGYAKRTRTDLYRLQKRGGKGVRGA-SRADDEVAQLFTTTNHQWILFFTNMGRVYRTKVWQLPEASRDARGGHVAGLLSFLPEE
HITRVMTLR---AK-YLLLATRAGLVKKTQLTAYDS-RQAGVIAINFRT-DELIGAE--GPDDDVLLISRKGQAIRFGE--LRPMGRATSGVTGMKFR-D
-DLLSMSVIEVERFVFTATDGGYAKRTLVSEYRRQGRGGLGIKAMALS-EDRGSLVGGLVVQA-DEVIAIRTSGQLTRSAVAEVPV-GRSTMGVKFVSVR
-KAVSIIALNP-
>tr|K7RJ27|K7RJ27_PROA4 DNA gyrase subunit A OS=Propionibacterium acidipropionici (strain ATCC 4875 / DSM 20272 / JCM 6432 / NBRC 12425 / NCIMB 8070) G
EEDFIPDDDVVVTITRGGYAKRTRIDNYRVQKRGGRGVRGA-AKGEDEVAHLFATTNHQWILFFTNMGRVYRTKVWQLPEASRDARGGHVAGLLSFLPEE
HITQVMTLR---DP-YLLLATRKGLVKKTALSAYDS-RAAGIIAINFRS-DELIGAE--GPEDDVLLISRKGQAIRFPD--LRPMGRVTSGVTGMKFR-D
-DLLSMSIISADRFVVTVTDGGFAKRTAVSEYRRQGRGGLGIKAMHLS-EARGSLVGGLVVSA-DEIMAIKNSGQVTRSAVSEVPV-GRSTMGVKFVSVK
-DAVSIIALNP-
>tr|A9KPP6|A9KPP6_CLOPH DNA gyrase subunit A OS=Clostridium phytofermentans (strain ATCC 700394 / DSM 18823 / ISDg) GN=gyrA PE=3 SV=1
MEDLIPDENTVIAMTRLGYIKRMTIDNFKSQHRGGKGIKGMQT-DEDFIEDLFMTTTHHYIMFFTNKGRVYRLKAYEIPESSRTARGTAIVNLLQLLP-E
RITAIIALK---DNRYLFMATKDGIVKKTKIKEYQN-RKTGLQAINLREDDELIEVK-TNS-KDIVLVTKNGMCIRFHE--VRNTGRASMGVIGMNLT--
-GVVAMQIHTQGKYLLTVSEYGLGKLTDLDEFTPQRRGGKGVKCYKIT-E-TGNVVGAKAVNE-HEVMIITNEGIIIRLEVNGISILGRITSGVKLINID
G-RVASLAKVK-
>tr|R5WDH5|R5WDH5_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:167 GN=gyrA PE=3 SV=1
MEDLIPVEDTVIAMTHKGYIKRMSSDNFRAQHRGGKGIKGMQT-EDDYIENLFMATTHHYLMFFTNKGRVYRMKAYEIPESGRTSRGTAIVNLLQLMP-E
KISAVISLK---DEEYLFMATKSGIVKKTHISEYEN-RKTGLQAINLREDDELIEVK-TNN-KDIILVTKHGMCIRFKE--VRPTGRTSIGVRGMNLG--
-EVVGMQMDTQGPNILLVSEFGMGKRTAVEDFSVQHRGGKGVKCYKIT-E-TGDVVGAKAVEG-TEVMLITNEGIIIRINVDDISILGRVTSGVKLMNLD
TNKIASIAKVR-
>tr|R7C8W1|R7C8W1_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:62 GN=gyrA PE=3 SV=1
MEDLIPVENTVIAMSHLGYIKRMTIDNFKNQHRGGKGIKGMQT-EEDYIENLFMATTHHYLMFFTNLGKVYRMKAYEIPEASRTSRGTAIINLLQLLP-E
KISAVISIK---EDKYLFMATKDGTVKKTPILEYAN-RKTGLQAITLRDGNELIEVK-TDN-RDIFLVTKRGQCIRFNE--VRTTGRTSIGVRGMKID--
-GVVAMQMDIQGPNLLMVSEFGMGKRTSIDEFAPQFRGGKGVKCYKIT-E-TGNVIGCKAVEG-TEIMLITTEGIIIRIGVDDISQLGRVTSGVKLMNLD
SDRIASIARVH-
>tr|R5EG74|R5EG74_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:590 GN=gyrA PE=3 SV=1
IEDLIKKENTVITMTKLGYIKRMTVDNFRAQHRGGKGIKGMST-DDDFIEDLFMTTTHHYLMFFTNSGKVYRMKTYEIPESARTSRGTNIVNLLQLNP-E
RITAVIALK---EGKYLFMVTKNGIVKKTPIMDYAN-RKTGLAAITLKDGDELIEVK-TDN-KDIIMVTKLGMCIRFNE--VRSTGRTSQGVIGMNLS--
-GIIGMQMDTQGEDLLIVSENGMGKRTSMEEFTPQRRGGKGVKCYKIN-S-TGNVVGMKAVND-NEIMLISTEGIVIRLECSSISELGRITSGVKLMKMD
GDTVASIAKVR-
>tr|A0A0K8J1P4|A0A0K8J1P4_9FIRM DNA gyrase subunit A OS=Herbinix sp. SD1D GN=gyrA PE=3 SV=1
MEDLIPNETTLIAMTKLGYIKRMTVDNFKSQHRGGKGIKGMQT-EDDFIEDLLMTMNHDYIMFFTNQGRVYRLKAYEIPEASRTARGMAIINLLQLMP-E
QITAIIPIK---EDRYLFMATKYGMVKKTPIKDYEN-RKSGLIAINLREGDELIEVK-TNG-KDVFLVTKKGMCIRFDE--VRPTGRSSMGVIGMSLD--
-DIIGMQLDTQGEYLLFVSAKGLGKRTAIDEFKVQFRGGKGVKCYKLT-E-TGEVVGVKAVNE-NEIMLITTEGIIIRILVSDISILGRITSGVKLINLD
ENFVASLAKVR-
>tr|R7I547|R7I547_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:411 GN=gyrA PE=3 SV=1
NEDLIPRENTVIARTSLGYIKRMTIDNFKSQNRGGKGIKGMQT-EEDYIEDLLMTTTHHYVNFFTNMGRVYRIKAYEIPEASRTARGTALVNLLQLQP-E
RITAVIPIR---DHKYLFMATKKGIVKKTSLTDYSK-RKSGLQAINLRDDDELIEVK-TNG-KDIFLVTKYGMCIRFSE--VRPTGRTSMGVIGINLT--
-QVVGMQLQTQGSHLLIVSENGLGKRTALEEFSLQYRGGKGVKCYKIT-E-TGNIVGVKAVND-NEIMLITTEGIIIRTMCNQISELGRITSGVKLMNID
DDKVASIAKVR-
>tr|R6YJP8|R6YJP8_9FIRM DNA gyrase subunit A OS=Roseburia sp. CAG:309 GN=gyrA PE=3 SV=1
MEDLIPVENTVIAMTHMGYIKRMTSDNFKSQHRGGKGIKGMQT-EEDYIEDLFMATTHHYLMFFTNKGRVYRIKAYEIPESSRTSRGTAIVNLLQLLP-E
KITAVIALR---EDKYLFMATKNGLVKKTSLSEYMN-RKTGLQAINLREEDELIEVK-TDD-KEIILVTKQGQCIKFKE--VRTTGRTSMGVRGMNLS--
-DVVGMQLDTQGEQLLLVSEYGLGKRTNIEEFGVQHRGGKGVKCYKIT-E-TGNVVGAKAVHD-QEIMLITNEGIVIRIEVSGISILGRITSGVKLMNLD
SDVIASIAKVR-
>tr|A0A0H5SZ93|A0A0H5SZ93_9FIRM DNA gyrase subunit A OS=Herbinix hemicellulosilytica GN=gyrA3 PE=3 SV=1
VEDLIPDETMLIAMTKLGYIKRMTIDNFKSQHRGGKGIKGMHT-DEDFIEDLFMARNHHFIMFFTNQGRVYRLKTYEIPEAGRTARGTAIINLLQLMP-E
KITAVIPIK---DNRYLFMATKKGIVKKTSVKEYEN-RKSGLIAINLREDDELIEVK-TDG-KDVFLVTKNGMCIRFNE--VRPTGRSSTGVIGMAID--
-DIVGMQLNSQGEYLLIASANGMGKRTSIDEFSLQHRAGKGVKCYKIT-E-TGNVVGVKAVNE-NEVMLITTEGIIIRIMVSDIPVLGRITSGVKLIHLD
DNYVASLAKVR-
>tr|W1TPN1|W1TPN1_9ACTO DNA gyrase subunit A OS=Varibaculum cambriense DORA_20 GN=gyrA PE=3 SV=1
MEDLIEEQDVVVTITRSGYVKRTRLDQYRSQKRGGKGIKGA-QREDDVVDHFFTTTTHHWLAFFTNKGRVYRAKAYELPEGGRDSKGQHVANLLAFQPEE
KIAQVLTFS---AE-YLALATRSGLVKKTRFTEYDS-RTGGLIAINLREPDEVVSAE--NGDDELLLVSHRGQSLRFLE--LRPTGRATSGVRGMKFR-G
-DLLAMTVIRP--DLLVVTEGGYAKRTSVEEYRVQGRGGLGIKVANLV-AERGGLVGALIVND-DEVMVIMHSGKVQRSRVDEVPR-GRNTQGVIFTRPA
-GAVLAVALNN-
>tr|E0N4E8|E0N4E8_9ACTO DNA gyrase subunit A OS=Mobiluncus curtisii subsp. curtisii ATCC 35241 GN=gyrA PE=3 SV=1
MEDLIPEEDVVVTITRGGYAKRTRVDAYRSQHRGGKGIKGA-SREEDQVEHFFTTSSHDWLLFFTNFGRVYRAKAYEIPEGGRDSKGQHVANLLAFQPDE
RIAQVLQVS---KD-YLVLATRLGFVKKTRLTDYDT-RTGGLIAIKLREADQLVSAC--DATDDLILVSRHGQSLRFNE--LRPMGRATSGVTGMRFR--
-DLLTMDVVRPEADLFVVTEGGYAKRTALSEYRVQGRGGLGIKVANLV-E-RGDLVGALVTED-SEVLVIMAGGKIVRSRVDEVSR-GRNTQGVIFSRAD
-GKVIAITLNV-
>tr|D0YU03|D0YU03_9ACTO DNA gyrase subunit A OS=Mobiluncus mulieris 28-1 GN=gyrA PE=3 SV=1
VEDLIPEEDMVVTITRGGFAKRTRVDAYRSQRRGGKGVKGA-QREDDQVEHFFTSSSHDWILFFTNFGRVYRAKAYEIPEGGRDSKGQHVANLLAFQPEE
RIAQVLHIS---KE-YLVLATKRGFVKKTHLTDYDT-RTGGLIAIKLREPDQLVSAV--DDTEDLILVSRDGQSLRFTD--LRPMGRSTSGVTGMRFR--
-DLLTMDVVRPGADLFVVTEGGYAKRTDLSEYRVQGRGGLGIKVANLV-E-RGKLVGALVTDE-SEVLVIMAGGKIVRSRVDEVSK-GRNTQGVIFSRAD
-DRVIAVTLNV-
>tr|K0YN91|K0YN91_9ACTO DNA gyrase subunit A OS=Actinomyces neuii BVS029A5 GN=gyrA PE=3 SV=1
MEDLIPEEDVVVTITRSGYAKRTRMDQYRSQRRGGKGVRGA-HRSDDVVEHFFTTTTHDWLLFFTNFGRVYRVKGYELPEGGRDAKGQHVANLLAFQPDE
HISQVLQIK---AD-YLVLATKRGLVKKTRLSEYDS-RSGGIIAINLRESDQLVSAV--NAQDDLIMVSRKGQSLRFTE--LRPTGRATSGVTGMRFR--
-DLLAMRRVEDDADLFVLTEGGYGKRTSLSEYRVQGRGGLGIKVANLV-E-RGDLVGALVVGG-DEVMVMMHGGKVVRSRVDEVSR-GRNTQGVIFSRPD
-RYVIGMTLNS-
>tr|S3YCP1|S3YCP1_9ACTN DNA gyrase subunit A OS=Propionibacterium sp. oral taxon 192 str. F0372 GN=gyrA PE=3 SV=1
DEDLVPNEECVITLTRGGYIKRTRIDQYRVQKRGGKGVRGA-SRSEDEVDAVFTAMSHDWLVLFTNLGRAYRIKAWHLPEGGRDAKGGHVAGLLSFLPDE
QIAQGIVLS---AE-YLLLATRKGLIKKTALSAYDS-RAAGLIAVSFRD-DELIGAE--NRDDDVLLISRKGQGIRFND--VRPMGRTTSGVTGMRFR-G
-DLLSMSIIPNESFVFTVTDEGYAKRTPVADYRLQNRGGLGIRAMRLK-DDRGGLVSAMVVAD-DEVISFKASGQVIRSSVADVSP-GRDTMGVKFVGLR
-NTVVAVTRNP-
>tr|S2W767|S2W767_9ACTN DNA gyrase subunit A OS=Propionimicrobium lymphophilum ACS-093-V-SCH5 GN=gyrA PE=3 SV=1
DEDFIPDEEMVVTITRGGYIKRTRIDQYRTQKRGGKGVRGA-SRAEDEVDHLFTITNHDWLVFLTNMGRAYRTKGWHLPESGRDSKGSHVAGILSFLPDE
HITQCFSLR---AE-YLLLATRKGLIKKTKLSAYDS-RQAGLIAINFRD-DELIGAR--NPEDDVLLISKKGQAIRFND--VRPMGRTTSGVTGMRFR-G
-DLLSMGVIPAELYVFTVTDEGYAKRTPVSEYRVQGRGGLGIKTMRLS-DERGGLIGGMIVTG-DEVISIKHSGQIIRSAVTDVSV-SRDTMGVKFVNTG
-KPVVAITLSP-
>tr|I6WS37|I6WS37_PROPF DNA gyrase subunit A OS=Propionibacterium propionicum (strain F0230a) GN=gyrA PE=3 SV=1
EEDFIADEDVVVTITHGGYAKRTRADQYRVQKRGGKGVRGA-TRADDEVAHLFKATNHEWLLFFTNLGRVYRAKVWQLPEAGRDAKGGHVAGLLSFLPDE
HIAQVLTLR---AP-YLLLATRRGFVKKTALSSYDS-RQAGVIAINFRE-DELIGAS--SSIDDVLLISRKGQAIRFQD--LRPMGRATSGVTGMRFR-G
-DLLSMAVLGGGRFVFTVTDGGFAKRTTVGEYRQQGRGGLGIKAMRLS-DGRGSLVGGLIVGG-DEVISIKQSGQVVRSAVADVPV-GRDTMGVKFVGVR
-DAVAAIALYP-
>tr|R9PKU2|R9PKU2_AGAAL DNA gyrase subunit A OS=Agarivorans albus MKT 106 GN=gyrA PE=3 SV=1
LEDLINEEDVVVTLSHEGYVKYQPLTEYESQRRGGKGAAT-KMKNEDFIEKLLVANTHDTVLCFSTVGKVYWMKVYQLPLASRQARGKPIVNLLPLT-DE
RITAIL--P--EEDKFILFATANGTVKKTPLTAFKR-LSSGIRAINLNDDDKLIGVDITNGNNEIMLFSDAGKVVRFNEKALRPMGRTAAGVRGISLD--
-GVVSLIVPTGDGDILTATENGYGKRTKLDEYPAKSRATKGVVSI--SE-RNGLVVGAVQVT-AQEMMLITNGGTLVRTRVNEVSLVGRNTQGVTLIRTS
-DKVVGLQRID-
>tr|T0GAM0|T0GAM0_9SPHN DNA gyrase subunit A OS=Sphingobium baderi LL03 GN=gyrA PE=3 SV=1
DEDLIEREDMVVTVTMQGYIKRTPLDTFRAQARGGKGRSGMATKDEDAVTELFVTSTHTPVLFFSTIGKVYRLKVWRLPEGGPATRGRPMVNLLPL-GGE
TISTVLPLP---SKLHVMFATARGSVRRNSMDAFTNIPSNGKIAMKFEGDDRLIGVA-DES-DDVLLATRQGKAIRFPD--VREQSRNSTGVRGIRLG--
-DVMSLSILHREQFILTVCANGYGKLSSAYEYRRTGRGGQGITNID---IRNGPVVASFPAT-QDQLMLVTDQAKLIRMGLD-LRVIGRNSAGVRLFNVA
-D-VVSAARIE-
>tr|X7E1T8|X7E1T8_9GAMM DNA gyrase subunit A OS=Marinomonas ushuaiensis DSM 15871 GN=gyrA PE=3 SV=1
MADLIDEAPMVVTISNTGYAKSQPLEEYQAQRRGGRGSSAS-MKDEDHIEHLLVTSSHDTIMLFSNFGKVYWMRVFDIPVASRGAKGRPIVNLLP-LRGE
SISALLPLPVVEASSYIFMATANGTVKKTALQHFARPRSTGLIALSLDETDELVGVSVTNGESDIMLVSSSGKTIRFKESDVRPMGRTAAGVRGIRLSEA
K-VVSLIVPQNDLAVLMACENGFGKRTLVDDFPVYGRGGQGVIGIQVSD-RNGPVIGAAQVDETDEIILITDQGTLVRTRVTEVSCQGRNTQGVTLIRLT
NDHLVGIERVV-
>tr|F2JXC4|F2JXC4_MARM1 DNA gyrase subunit A OS=Marinomonas mediterranea (strain ATCC 700492 / JCM 21426 / NBRC 103028 / MMB-1) GN=gyrA PE=3 SV=1
IADLIDEAPMVVTISDTGYAKSQPLEEYKAQRRGGRGSSAT-MKDEDHISHLLVTSSHDTVMLFSNFGKVYWLRVFEIPVASRTAKGRPIVNLLPLA-GE
HISALLPLNDEMEDSYIFMATANGTVKKTAVEYFARPRSTGLIALSLDENDELVGVAQTSGENDIMLVSSSGKTIRFKESDVRAMGRTAAGVRGIRLADY
K-VVSLIVPQ-GCSVLFACENGFGKRTLTEDFPVYGRGGQGVIGIQVSE-RNGPVVGATQVEDTDEIMLISDQGTLVRTRASEVSCQGRNTQGVTLIRLM
NDHLVGVERVV-
>tr|F6CVE7|F6CVE7_MARPP DNA gyrase subunit A OS=Marinomonas posidonica (strain CECT 7376 / NCIMB 14433 / IVIA-Po-181) GN=gyrA PE=3 SV=1
IADLIDEAPMVVTISDTGYAKSQPLEEYKAQRRGGRGSASA-MKEEDHINHLLVTSSHDTVMLFTNFGKVYWLRVFEIPVASRSSKGRPIVNLLP-LAGE
HVSALLPLTAPEASSYIFMATANGTVKKTAMEHFARPRSTGLIALNLDETDALVGVAQTSGEDDIMLVSSSGKTIRFSEGDVRAMGRTAAGVRGIRLGEA
K-VVSLIVPQEGAAVLMACENGYGKRTLVDDFPVYGRGGQGVIGIQVSD-RNGPVVGATQVEETDEIMLITDQGTLVRTRVSEVSCQGRNTQGVTLIRLT
NDHLVGVVRVE-
>tr|A3Y7B6|A3Y7B6_9GAMM DNA gyrase subunit A OS=Marinomonas sp. MED121 GN=gyrA PE=3 SV=1
VADLIDEAPMVVTISNTGYAKSQPLEEYQAQRRGGRGSSSS-MKDEDHISHLLVTSSHDTIMLFSNFGKVYWLRVFEIPVASRNAKGRPIVNLLP-LSGE
SISALLPLVAPDAESFIFMATANGTVKKTAMQHFARPRSTGLIALSLDESDELVGVSITNGNDDIMLVSSTGKTIRFKESDVRAMGRTAAGVRGIKLAEA
K-VVSLIVPEEGMSVLTACEHGYGKRTAIDDFPVYGRGGQGVIGIQVSD-RNGPVVGAVQVADDDEIILITDQGTLVRTRVSEVSCQGRNTQGVTLIRLT
NEQLVGVVRVV-
>tr|A0A0K6IH40|A0A0K6IH40_9GAMM DNA gyrase subunit A OS=Marinomonas fungiae GN=gyrA PE=3 SV=1
IADLIDEAPMVVTISDTGYAKTQPLEEYKAQRRGGRGSASG-MKDEDHISHLLVTSSHDTVMLFSNFGKVYWLRVFEIPVGSRASKGRPIVNLLP-LAGE
HISALLPLTAPAASSYIFMATANGTVKKTAMEHFARPRSSGLIALKLDESDALVGVAQTSGNDDIMLVSSSGKTIRFKETDVRSMGRTAAGVRGIKLAEA
K-VVSLIVPSAETAVLMACENGYGKRTMISEFPVYGRGGQGVIGIQVSE-RNGPVVGATQVEESDEVILITDMGTLVRTRVAEISCQGRNTQGVTLIRLS
NDRLVGVERVV-
>tr|B1XVQ8|B1XVQ8_POLNS DNA gyrase subunit A OS=Polynucleobacter necessarius subsp. necessarius (strain STIR1) GN=gyrA PE=3 SV=1
TEDLITPQDLVVTLSNTGYMKSQPLSEYRAQKRGGRGQAAA-TKNEDWIETLFVANTHDTILCFSDRGRMYWLKVWEVPQGSRTSRGKPIVNMFPLI-GE
KITVILPIKGY--NQYVFMATSLGTVKKTRLSDFSNPRKAGIIAVDLNENDFLVGAAITDGQHDVMLFSDAGKAVRFDENDVRPMGRTARGVRGMNLG--
EGVIAMLVAPAPSSVLTATENGYGKRTPITEYTRHGRGTKGMIAIQTSE-RNGKVVAAALVSPEDQIMLITTGGVLVRTRVSEIREMGRATQGVTLINVD
EGRLSGLQRIA-
>tr|A0A0K1Q9L7|A0A0K1Q9L7_9DELT DNA gyrase subunit A OS=Labilithrix luteola GN=gyrA PE=3 SV=1
DEDMIQEEDMVVTISHAGYIKRTHPSAYRAQKRGGKGKIGMEA-EEDWVTQLFVASTHAYVFFFSDRGKVYVKKVYEIPIAARNAKGRAIVNFVGMEPGE
KVAAIVE---IEG-KFVVTITKRGQIKKTAVTEYENFRQKGIIGVKIEGDDQLLSAA-TNGGCELLIATKLGQSIRFAE--VRSMGRGTVGVKAIDVA--
-DVVGMAVTDPRPFVLAVCENGYGKRTNLEEFRQQNRGGKGIILI--SR--NGPVVDVKLVKDGDEIMLITDKGQTLRTAVAEVRETGRNAQGVKIMSVE
-GRIVALERMA-
>tr|A9GW54|A9GW54_SORC5 DNA gyrase subunit A OS=Sorangium cellulosum (strain So ce56) GN=gyrA PE=3 SV=1
MEDLIQEEDMVVTISHAGYLKRTPTSTYRAQRRGGKGMVGMEA-EEDWVSQLFVASTHSYVFFFSDKGKVFVKKVYEIPQAPRNAKGRAIVNFV-GEPGE
KVAAITPVP---GETFVVTLTRRGQIKKTALNEYENYRDKGIIGVRIEEGDQLFTAA-TDGKRELVIATRSGMSIRFPE--VRPTGRATMGVKGIELD--
-DVVGLGVSGDRDRVLAVCERGYGKQTPLEEFRLQSRGGKGVILI--SR--NGPVVGVAMVSPSDEVLIVTDRGQMIRTKTSEIRETGRNAQGVRIMHVG
-DRVVAVEAFA-
>tr|W0PCB2|W0PCB2_9BURK DNA gyrase subunit A OS=Advenella mimigardefordensis DPN7 GN=gyrA PE=3 SV=1
TEDLITPADMVVTLSNSGYIKSQPLSEYRAQKRGGRGQATA-MKDDDWIDQLFIANTHDYLLCFSDRGRVYWLKVWEVPQGTRGSRGRPIVNMFPLI-GE
KITVVLPVREF--TNFVFMATSRGTVKKTPLSDFSNPRKAGIIAVALDEGDYLIGADLTDGEHDVMLFSDAGKAVRFDENDVRPMGRTARGVRGMNLD--
GDVISLLVAGDSQSVLTATENGYGKRTSISEYTRHGRGTKGMIAIQTSA-RNGKVVGAVLVNPADEIMLITTGGVLVRTRVSEVREMGRATQGVTLISVD
DGTLSGVRRVV-
>tr|A0A077DE29|A0A077DE29_9BURK DNA gyrase subunit A OS=Basilea psittacipulmonis DSM 24701 GN=gyrA PE=3 SV=1
TEDLITPTDMVVTMSNTGYIKSQPLSEYRAQKRGGRGLATA-TKEDDWVESLYVANTHDYLLCFSNYGRLYWLKVWQVPQGTRGSRGRPIVNMFPLQ-GE
RITATLPVKEF--DQYVFMATSRGTVKKTPLSDFSNPRKAGIIAVGLKEDDYLIGVGLTNGQSDVMLFSDAGKAVRFSESDVRPMGRAASGVRGMNLD--
KDVIAMLVTSDGFSVLTATENGYGKRTAIEEYTRHGRGTKGMIAIQTSE-RNGKVVAATLVKETDEIMLITNGGVLVRTRVSEIREMGRATQGVTLIRID
DDKLQGVSRVA-
>tr|V8FRQ0|V8FRQ0_9BURK DNA gyrase subunit A OS=Pelistega indica GN=gyrA PE=3 SV=1
TEDLITPTDMVVTMSNSGYIKSQPLSEYRAQKRGGRGQATA-MKEDDWINQLFIANTHDYLLCFSNHGRVYWLKVWEVPQGTRNSRGKPIVNLFNLQ-GE
RITVVLAVKEF--NQYVFMATAQGTVKKTPLSDFSNPRKAGIIAVNLDEGDYLIGAELTDGKHDVMLFSDAGKAVRFDENDVRSMGRTARGVRGMNLE--
EGVISLLVAGDEQSVLTATENGFGKRTSITEYTRHSRGTKGMIAIQTSE-RNGKVVAAVLVEPSDEIMLITTGGVLVRTKVDQIREMGRATQGVTLIRVD
EGVLSGIRRVA-
>tr|A0A060Q0F8|A0A060Q0F8_9RICK DNA gyrase subunit A OS=Wolbachia endosymbiont of Cimex lectularius GN=gyrA PE=3 SV=1
AEDLIPQEDMVVTVTMNGYIKRVKLSHYRTQRRGGKGKLGQGLKEEDVTTKLFVGNTHTSLLFFSNIGRVYRLKVYKLPLAEPTARGRALVNVFPL-TGE
TITNIMPLP---ENQNIVFATAHGNIRRNSLADFHYIPSNGKIAIKLDG-DKLVSVK-NEI-DHVLLSTTLGKSIRFVD--VRQKSRNSDGVRGIKLV--
-DVISMTILNGEEFILTITENGFGKRTSAYEYRVTNRGGVGITNIL---TRNGSVVASFPVE-GDNIMLITDKGKLIRISVDDIRIAGRSTQGVTLFKTE
-K-VVSAAKIE-
>tr|W2UZT7|W2UZT7_9RICK DNA gyrase subunit A OS=Candidatus Xenolissoclinum pacificiensis L6 GN=gyrA PE=3 SV=1
DEDLILKEDMVVTFTNMGYIKRVKLSHYRSQKRGG-G--LQD--ED-FTEKIFVVDTHTEILFFSTKAKVYKLKTYLLPLE-PASRGRALVNSL-NEG-E
C--TIMPVTA-D--SSMVFITSHGKVKRNKFSDFHY-P-NGKLALSLS--DMLVA---A---HDVFVATYYGKSI------IRLFGRVAGGVRGIKLS--
NDVVGSSVLSGEQFILSVTENGYGKITSA-EYR-VNRGGAGIVNV---TKRNGYV-ASFPIE-DSHIILVTNKGQLIRIKT-DISI-GR---GVILLKTK
D-RVVSVAQIS-
>tr|A0A087CHL6|A0A087CHL6_9BIFI DNA gyrase subunit A OS=Bifidobacterium psychraerophilum GN=gyrA PE=3 SV=1
VEDLIAEEHVVVTVTHSGFIKRTKADEYRAQHRGGKGIKGA-KREDDVVDHFFLTSTHNWLLFFTNKGRVYRIKAYEIPEGSRDSKGQHVANLLQFGPEE
KIQQVLSIH---AQ-YLVLATRTGKVKKTRLNEYDS-RQGGLIAVRLMDQDELVGAA--NAQDDIILVSRLGMSVKFPD--LRPMGRQTAGVQGMRFR--
-GLLSMDVVPE-EDLFVVTNEGYAKRTALAEYRLQGRNGYGVKAIQLV-E-RGSLVGALVVGE-DQVLAIMKSGKVIRSNVNEVKR-GRTTQGVTLAKPD
-GEILSIARNE-
>sp|P35810|GYRA_FIBSS DNA gyrase subunit A OS=Fibrobacter succinogenes (strain ATCC 19169 / S85) GN=gyrA PE=3 SV=2
DEDLIAEEEQVITLSKEGYIRRLPIDTFKAQNRGG-G--IAG--ED-NVEQIFTASTHSYLLVFTNKGRVYWTKVYRLPEA-RNGKGRPIVNFV-ATG-E
K--AIVPVR--GGYFCLVFATKKGIINKMDLTLFSR-R-AGVNAISLD--DELVK---VAEKDLLMIATKNGQAV------FRAMGRGTHGVKGITLAE-
-DVISLLW---GNKILTITEKGYGKRSEP-SYR-TRRGSKGVRNL---TDKIGAV-FVESVA--YDLIITSKDGQVIRIKA-DIRL-GR---GVKAITLR
G-VVKDATALP-
>tr|Q2CCL5|Q2CCL5_OCEGH DNA gyrase subunit A OS=Oceanicola granulosus (strain ATCC BAA-861 / DSM 15982 / KCTC 12143 / HTCC2516) GN=gyrA PE=3 SV=1
DEDLIEREDMVVTVTQGGYIKRTALADFRSQKRGGKGLSGGGLKEEDVVTTLFVANTHTQLLFFTTDGMVYKLKTWRLPLGGRTSRGKAIVNILP-IPGV
SIAAIMPVD---DDLNIVFATSAGDVRRNRLSDFTNVMRNGKIAMKLPESVSLVNAR-SED-DDVMLVTDAGRAIRFPD--VRVSGRSSTGVRGIRLQ--
-DVVSMAVIRHENLLLTITAKGQGKLSSSHGYPVRGRGGQGVSATD---ARG-PIVSVFPVE-DDQIMLVTNQGQSIRVPVD-ISFRSRSAGGVRVFNTA
-G-VVSVAWIA-
>tr|A0A0J6NK53|A0A0J6NK53_9NEIS DNA gyrase subunit A OS=Chromobacterium sp. LK11 GN=gyrA PE=3 SV=1
IEDLITPQDMVVTISHTGYIKAQPIDDYSAQRRGGRGQAAA-TKDDDFIDTLFVANTHDFVLCFSSRGRCYWRKVYDLPQGGRQSRGKPMVNVLPLE-GE
KINALLPVKEF--DQYVFMATADGTVKKTPLRAFSKPRAAGIIAINLDEGNYLIGVALTCGGDQVMLFSDAGKSVRFSE-QVRPMGRTSRGVRGMKLG--
EGLISLLVTNSDQMVLTASNGGYGKRTRTGDFRLTSRGTQGVIAMDLTD-KTGFLVAASLVEETDDVMLITTGGVLIRTKVAEVRETGRSAQGVRLINLD
EGQLIGLEKVA-
>tr|C1D8N0|C1D8N0_LARHH DNA gyrase subunit A OS=Laribacter hongkongensis (strain HLHK9) GN=gyrA PE=3 SV=1
LEDLITPQDMVVTLSHTGYMKTQPVTDYQAQRRGGRGQAAA-TKDEDFIENLFVANTHDFLLCFSSAGRMYWLKVYELPQGSRQSRGKPIVNLLPLV-GE
KINAILPVKGF--TEYVFMATARGTVKKTPLSAFSNRRSAGIIAVDLDEGDYLIGAAVTSGNSEVMLFSDAGKAVRFDE-DVRPMGRNARGVRGMELG--
DAVIGMLVSNETSQVLTATANGYGKRTPIGDYRKSRRGTQGVIAIDTGE-RNGALVAVALVADSDELMLMTTGGVLIRTRVSEVRETGRAAQGVRLINLD
AGQLVSLEKIA-
>tr|A0A0J6PB84|A0A0J6PB84_CHRVL DNA gyrase subunit A OS=Chromobacterium violaceum GN=gyrA PE=3 SV=1
IEDLITPQDMVVTISHTGYIKAQPIDDYSSQRRGGRGQAAA-TKDDDFIETLFVANTHDYVLCFSSRGRCYWRKVYDLPQGGRQSRGKPMVNVLPLE-GE
KINALLPVKEF--DQFVFMCTANGTVKKTPLVDFSRPRTAGIIAVNLDDGDNLIGVALTHGDDQIMLFSDAGKAVRFSE-DVRPMGRNATGVRGMMLG--
DDVISLLVSNSQQMVLTASDGGYGKRTCVGDFRRTSRGTQGVIAMDLTD-KTGLLVAASLVEETDDIMLITTGGVLIRTKVAEVRETGRSAQGVRLINLD
EGKLIGLEIVA-
>tr|A0A0K6H1G8|A0A0K6H1G8_9NEIS DNA gyrase subunit A OS=Gulbenkiania indica GN=gyrA PE=3 SV=1
IEDLITPQDMVVTISHTGYIKAQPMDDYRAQRRGGRGQATA-TKDDDFIDTLFVANTHDYVLCFSSFGRCYWIKVYDLPQGGRASRGKPMVNVLALA-GE
RINALLPVKEF--DQYIFMATANGTVKKTPLVDFSRPRTAGIIAVNLDEGDNLIGVALTHGNDQIMLFSDTGKAVRFNE-DVRAMGRNATGVRGMALA--
EGVISLLVTNSEQMVLTASDGGYGKRTRIGEFRHTSRGTQGVIAMDLTE-RTGLLVAASLVEETDDVMLITTGGVLIRTKVAEVRETGRAAQGVRLINLD
EGKLIGLEKVA-
>tr|A0A0J5JEU4|A0A0J5JEU4_9NEIS DNA gyrase subunit A OS=Vogesella sp. EB GN=gyrA PE=3 SV=1
IEDLITPQEMVVTLSHTGYLKAQPVDDYQSQRRGGRGQAAA-TKDDDFINTLFVANTHDYVLCYSSFGRCYWIKVYDMPQGGRTSRGKPIVNVLPLA-GE
KINAMLPVKAFVKGPFVFMCTANGTVKKTPLEAFSRPRSAGIIAVKLDEGDKLVGVALTSGNDQIMLFSNAGKAVRFDE-GVRAMGRNATGVRGMALG--
EGVISLLVANSEQQVLTASDGGYGKRTRVGEFRHTSRGTQGVIAMDLTD-KTGLLVTASLVEDSDDVMLITTGGVLIRTKVDQVRETGRAAQGVRLINLD
DGKLICLVKVA-
>tr|A0A0F3KW29|A0A0F3KW29_9NEIS DNA gyrase subunit A OS=Aquitalea magnusonii GN=gyrA PE=3 SV=1
IEDLITPQDMVVTISHTGYIKTQPIDDYRSQRRGGRGQAAA-TKDDDFIDTLFVANTHDYVLCFSSKGRCYWIKVYDLPQGGRNSRGKPMVNVLPLA-GE
KINALLPIKAFAKGPFIFMCTANGTVKKTPLEAFSRPRTAGIIAVRLDEGDNLIGVALTSGNDQIMLFSDAGKAVRFSE-DVRAMGRTAGGVRGMMLG--
EGVISLLVTNSEQQVLTASDGGYGKRTRTGEFRHTSRGTQGVIAMDLTD-KTGLLVAASLVEDSDDVMLITTGGVLIRTKVSEVRETGRSAQGVRLINLD
EGKLIGLEKVA-
>tr|R6XCH3|R6XCH3_9FIRM DNA gyrase subunit A OS=Firmicutes bacterium CAG:313 GN=gyrA PE=3 SV=1
DADLIPEEDVIITITNRGYIKRMTVDTYRAQRRGGKGITGSKM-EDDFIEKVIYTSTHDNLLFFTNFGKVYLLKAYQIPG-SRISKGLPLINLLKFEAEE
KLAAVINVK---EPGYVIFGTKNGIIKKTELIQYKNIRSTGIRAIILGEQDELIAVARTNGRQDIIFGASNGKAACFN---VRATNRAASGVKGIRVA--
-RAIGLVAVN-EDEITVVTEFGYGKRTPTSDFKIKGRNGKGVKYMNITE-KSGRPVSLAPST-EDDLMIITDKGMVIRTYLADISV-GRDTQGVRVIKLN
EGTVSSIAIVP-
>tr|R9LNF4|R9LNF4_9FIRM DNA gyrase subunit A OS=Firmicutes bacterium M10-2 GN=gyrA PE=3 SV=1
DEDLIPREDIIITLTESGYIKRQPVDTYHTQNRGGRGIKSMTL-DEDSVDTMVAMTTHNHILLFTNKGRVYRLKGYNIPNS-RTAKGLPIVNIIELQSDE
KVQTLLPVPE--GFRSLLFVTKNGLAKRTAVQEFDNINKNGKIAITLKEGDELRYVKGTTGKDEVIIAGNNGKAVRFD---IRLMGRSASGVQGFNTD--
-EVIGVALS--GETVLVASENGYGKRSKFEDFRLTSRGKKGVRALHITE-KTGNLVSLLAVH-DEDALIVSSNGIMIRIQLSGIGI-GRNTQGLKLINLS
-GKVTKVTLVN-
>tr|A0A0F3MI48|A0A0F3MI48_9RICK DNA gyrase subunit A OS=Orientia chuto str. Fuller GN=gyrA PE=3 SV=1
VEDLIPEEEVVVTVTLAGYIKRVPLATYRAQKRGGKGRIGSSVQNEDIVTHLFIENTHTSILFFSNIGQVYTLKVYKLPLGTPQSKGRPIINMLSI-KNE
TITNIMPMP---DKKYIIFATKHGNIRRNDLSDFKHIASNGKIAIRLDE-DRLISVK-DED-NHVLLATKNGKAIRFPD--LRVKSRTSDGVKAIRLA--
-DVISMTILKGEEFILTVSENGYGKFSSAYEYRVTNRGGKGIANMN---SKTGMVVSVLPAC-DNELMLITSSGKIIRCQLNSVRITGRSTSGVILFKTS
-D-VVSIDTIK-
>tr|K2FKE9|K2FKE9_9BACT DNA gyrase subunit A OS=uncultured bacterium (gcode 4) GN=gyrA PE=3 SV=1
DEDLIEREDMVVTITSGGYIKRTPLIEFRSQNRGGKGLSSMATKEDDVVTTLFVANTHTNLLFFTTDGMVYKLKTWRLPLAGRTAKGKAMVNILP-IAGI
SIAALMPVD---EDLQIVFATSDGDVRQNDLSDFTNVMRNGKIAMKLPEGVSLVNAA-DEN-DDIMLVTALGRAIRFPE--IRVKSRGSTGVRGIRVG--
-DVVSMSIIRHEDLILTITTSGSGKLSSSHDYPVRGRGGMGVKAMD---ARGGPLVASFKVD-SDQIMLATSTGQSIRVPVE-ISFRSRSAGGVKVFNTG
-G-VVSVARVA-
>tr|W3RG28|W3RG28_9BRAD DNA gyrase subunit A OS=Afipia sp. P52-10 GN=gyrA PE=3 SV=1
DEDLIQREDMVVTVSHAGYVKRVPLSTYRAQKRGGKGRSGMQTREEDFVSRLFIASTHTPVLFFSSRGQVYKEKVWRLPMGAANARGKAMINILPLEQ-E
RITTIMPLP---GDLDVMFATTGGTVRRNKLSDFADVRRSGIIAMKLGEGEAIVDVQ-T-E-DDVLLTAAGGQCIRFPD--VRVSGRTSMGVRGIALA--
-DVISLSILHHEQFVLTISENGYGKRTSSFEYRTTGRGGKGIVAMSV--GRNGKLVASFPVE-SDQIMLVTDAGQLIRCPVDGIRIAGRSTQGVIVFDTA
-G-VVSVEHIG-
>tr|V2TZ55|V2TZ55_9GAMM DNA gyrase subunit A OS=Acinetobacter nectaris CIP 110549 GN=gyrA PE=3 SV=1
REDLIPEEQIVLTVSQTGYAKTQPLSDYQAQRRGGRGSATS-M-DDDIIQHLIVTSNHSTVLCFTNVGKVYRLKAFEVPQASRGAKGRPIVNLLPLEPNE
TITAILPVK---EDHYVFMATASGTVKRVDLSQFSNVRSNGLRAIELNEEDTLIGVAITDGKQQIMLFSNEGKAIRFA---VRAMGRTARGVRGMRVTAA
LIIVSLVVVP-NGEVLCACAKGYGKRTPVDDFPTKKRGGKGIIAI--SE-RNGELVGAVSID-SKEMLLISDGGTLVRTRASEVATTGRNAQGVRLIRLQ
--VLVGVVSIE-
>tr|F2JSI8|F2JSI8_CELLD DNA gyrase subunit A OS=Cellulosilyticum lentocellum (strain ATCC 49066 / DSM 5427 / NCIMB 11756 / RHM5) GN=gyrA PE=3 SV=1
IEDLIDEENIVVTITQLGYIKRIPLDTYKNQNRGGKGIIGVNT-EDDFIKQLFVTTNFNYIMFFTNKGKAYRIKGYRIPEG-RTARGTAIVNLLELDKDE
KITAVFPIK---DNTFLTMVTKKGQIKKTPLKDFRN-RKGGLIALSLNEEDELVDVH-TTS-DAILVATRNGQGIMFDA--VRPMGRTARGVRAINLG--
-TVIGATVPK--EQILTTTEKGLGKRTQIEAFRAQKRGGKGLRINKIT-E-TGCIIGVASVSE-DELLLITSQGIIIRIKVAQISSIGRNAQGVKLINVA
DDQVVCMEKVN-
>tr|A0A0M2NYA8|A0A0M2NYA8_STACC DNA gyrase subunit A OS=Staphylococcus cohnii subsp. cohnii GN=gyrA PE=3 SV=1
DEDLIPEEQIVITLSHNNYIKRLPVSTYRAQHRGGRGVQGMQT-EEDFVSQLVTLSTHDHVLFFTNKGRVYKLKGYEVPELSRQSKGIPVVNAIELDN-E
TISTMIAVK---EEDYLVFATLNGIVKRSALRNFSH-NKNGKIAIGFKEDDELIAVR-TDG-DDVLIGTAHGSLIRFNE--LRPLGRTAAGVKGITLR--
-GVIGLDVTKADDEILVVTENGYGKRTPVSEYRLSNRGGKGIKTATIT-E-NGQVVCITSVEK-EDLMIVTNAGVIIRIGVEDISQNGRAAQGVRLIKLN
D-FVSTVAKVD-
>tr|A0A0M1E516|A0A0M1E516_STEMA DNA gyrase subunit A OS=Stenotrophomonas maltophilia GN=gyrA PE=3 SV=1
ILDLIAPEDVVVTVSHAGYVKRQPVSVYRAQRRGGRGSAAA-TKEEDFIEQLWLVNTHDTLLTFTSSGKVFWLPVYQLPEAGSNARGRPIINWIPLE-GE
RVQAVLPVREYADGQFVFFATKNGTVKKTPLGEFAFRLARGKIAINLDEGDALVGVGLTDGQRDILLFASNGKTVRFGED-VRSMGRTATGVRGIRMPAE
-EVVSLIVAESVQYILTATENGYGKRTPLPDYPRKGRGTQGVIGIQTTE-RNGKLVAAVLMGSRDEVLLISDGGTLVRTRGSEISRVGRNTQGVTLIRLS
KDKLQAVERMD-
>tr|A0A0F3L5U8|A0A0F3L5U8_9GAMM DNA gyrase subunit A OS=Acinetobacter brisouii GN=gyrA PE=3 SV=1
REDLIPEEQVVLTVSKTGYAKTQPLSDYAAQRRGGRGSATS-M-EDDYIQHLIVASNHATVLCFTNVGKVYRLRVFEVPQASRGAKGRPMVNLLPLDANE
TITAILPLT---EDHYVFMATASGTVKRVELAQFANIRANGLRAIELNEEDTLIGVAITDGNQQIMLFSNEGKAIRFA---VRAMGRTAKGVRGMRVAAT
VIIVSLVVVP-TGEVLCASANGYGKRTPVDDFPTKKRGGKGVIAI--SE-RNGELVGAVAID-TKELMLISDGGTLVRTRASEVATTGRNAQGVRLIRLG
-NTLVGVEAID-
>tr|E7RXI9|E7RXI9_9BURK DNA gyrase subunit A OS=Lautropia mirabilis ATCC 51599 GN=gyrA PE=3 SV=1
IEDLITPQDMVVTLSNSGYIKAQPLSEYRSQRRGGRGQAAS-TKDDDWVDQLFIANTHDTILCFSDRGRVYWLKVWEVPQGSRASRGRPIVNMFPLA-NE
KITVVLPIKTF--EHYVFMATSLGTVKKTALSDFSNPRKAGIIAVDLDEGDYLIGAAVTDGEHDVMLFSDAGKAVRFSEGDVRAMGRTARGVRGMALE--
EGVIAMLVADD-RSVLTATENGYGKRTPLIEHTRHGRGTKGMIAIQSSE-RNGRMVAAILVEEGDEIMLITTGGVLVRTRVDEIREMGRATQGVTLIGVE
EGTLSRVQRVV-
>tr|T0LMQ6|T0LMQ6_9EURY DNA gyrase subunit A OS=Thermoplasmatales archaeon I-plasma GN=gyrA PE=3 SV=1
EEELIPHEIDTIVLTEDNRISRIEADTFSAQKRGGKGVYT--G---SEIKQVITCDSHDRVFFFSDVGKVFQMKAYSIPKGERRSRAKLISAVFENMKGR
-IVFIMSEK-E--KKYLLFVTERGRVKKTEISQYTNIRSNGLIALKLRPGDLLKDVFT-SGKEKVALLSTDGRLVLVDE--FRSMGRPASGVTGIRFA--
-KVASDATIVS-DEMIVISEKGLGKRVSVEDFTMRHRGAKGMRAI--TE-RTGKPIYVSSINENDELLIITKNGKTIRTGVAAIPQKGRNAQGVKLIDLD
-GLVVSVTRIS-
>tr|A0B8Z5|A0B8Z5_METTP DNA gyrase subunit A OS=Methanosaeta thermophila (strain DSM 6194 / JCM 14653 / NBRC 101360 / PT) GN=gyrA PE=3 SV=1
PEDLIQDEEVAVIITNNGYIKRQPLSVYRMQRRGGKGSIGAET-SEDFVTDIFTASTLDYLMIFTDRGKAHWLRVYEIPMVSKVARGRPIASLLQLEE-E
RITEAIPVE----DEYIVLATRNGSIVKTPLRAFSN-RRGGIKAVNLR-GDSLVAAR-TDG-RELIVATKKGKAIRFHE--VRSSGRGSMGVKAINLS--
DELISMDVVKEGETLFTITTQGYGKRTELSEYPLQRRGGKGVKNID---T-RGDVVAAITVSD-DGLLITTKEGVMIRIAASDVRVQGRATQGVKIMDVK
-GEISDVARVD-
>tr|C9P504|C9P504_VIBME DNA gyrase subunit A OS=Vibrio metschnikovii CIP 69.14 GN=gyrA PE=3 SV=1
MEELIAREDVVVTLSHEGYVKYQVLTDYEAQRRGGKGSAT-RMKDEDYIERLLVANTHDNILCFSTRGKTYRLKVYQLPLASRTARGKPIVNLLPLE-NE
RITAIL--P--SEDKFIFMATGDGTVKKTSLDQFSN-RANGLIAVNLRDDDSLIGVEITDGESDIMLFSKSGKVVRFNEKGVRPMGRTASGVRGMKLV--
-GVVSLIVPKTDGDILTVTENGYGKRTQLSEYPAKSRATQGVVSI--SE-RNGKVVGAVQAD-GDEFMMITNAATLVRTRVSEVSQVGRNTQGVTLIRTS
-GKVVGLQRIE-
>tr|E1IGI9|E1IGI9_9CHLR DNA gyrase subunit A OS=Oscillochloris trichoides DG-6 GN=gyrA PE=3 SV=1
DEDLIPDVRVLITLTDRGYVKRQATDVYRTQRRGGRGVRAMTTREQDLVRHLLTCGSHDNLLFFTDKGKVYQLKAHEVPDSARTAKGLPLVNLISLDPGE
QVTSMLAVPDYD-GEYLVMATHRGKIKRTQLSEYSQVRSNGLIAIGLEEGDVLGWVRVSNGHEDVLMTTVKGQTIRFQQQAVRSMGRPATGVNGINLSEG
DRVISMELAIPDSDLLVVTARGFGKRTELGDYPTKGRATGGVITIRLRP-GDEVA-GAAIVNQRSLLTFVTAAGVVMRTSAGEISQLSRATQGVTVVNPD
DGRVAALSVEE-
>tr|A0A0G1YZV5|A0A0G1YZV5_9BACT DNA topoisomerase (ATP-hydrolyzing) OS=Parcubacteria bacterium GW2011_GWF2_50_9 GN=UY62_C0047G0001 PE=4 SV=1
EEDLIPDEDAVLVLTKGGYVKRTDPEEYRKQRRGGIGVVDLDTKDEDFVTHVITGTAHNDLLFFTDMGKAYQIKMYEIPEARRATKGKSVMNFLQLGAEE
KVTSILPMPKEVKALSLLMITRAGIGKKTKAASFHDVRRSGLIAIKLKAGDELVSASFVEKGDEAVLVTGKGQSIRFKVSDIREMGRGASGVKAMRLKKG
DTIVGTGIIGKHPELLVIMKNGYGKRTKLKEYKTQKRGGSGVKTAKISS-KTGDLIAAHVITSNEEVVAISRKSQVIRTDVKGIATLSRQTQGVRIMKLR
EGSIASLTCL--
>tr|A0A0G1VGU9|A0A0G1VGU9_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWA2_47_64 GN=gyrA PE=3 SV=1
EEDLIPDEDAVLLLTKGGYIKRTDPEEYRKQRRGGVGVVDLDTKDEDFVTHVITGTTHNDILLFTDKGKAFQIKMYEIPEGRRATKGKSVMNFLPLAADE
KVTSILPMPKEVKKLSLFMMTKNGVGKKTAAASFHDVRRSGLVAIKLKFGDELVSASFVEKGDEAILVTGKGQSIRFKESDIREMGRGASGVRAMRLRKG
DSIVGTGIISRHPELLVIMKNGYGKKTKLKEYKTQKRGGSGVKTAKITS-KTGELIAAHIVTSEEEVVAISRKSQVIRTGVSEIASLGRQTQGVRIMKLR
EGSIASLTCL--
>tr|A0A0G1HDB8|A0A0G1HDB8_9BACT DNA topoisomerase (ATP-hydrolyzing) OS=Parcubacteria bacterium GW2011_GWA2_44_15 GN=UW34_C0010G0005 PE=4 SV=1
EEDLIPDTESVLVLTKGGYIKRTDPEEYRKQKRGGVGVVDLDTKEEDFVTTFLTTTTHSDLLFFSDKGKAYQIKMYEIPEAKRATRGKSIMNFIPLSDEE
KITSILAMPKEIKTLSLMMVTRSGVGKKVAAKNFHDVRRSGLIAIKLQQNDQLISASFVEKGDECIVVTKNGQSIRFKESDIREMGRNAGGVRVVRLKKN
DALVGADVIKKNPALLVIMENGYGKKTLLKEYKVQKRGGSGIKTAKING-KTGALMASKVIDEETEEVKNQGRSKQIHRGT---LLL---FQGLE-----
------------
>tr|A0A0G1UKF3|A0A0G1UKF3_9BACT DNA topoisomerase (ATP-hydrolyzing) OS=Parcubacteria bacterium GW2011_GWA1_48_11b GN=UY24_C0012G0007 PE=3 SV=1
EEELVPEEDSLFMLTRGGYIKRMPPEELKAQKRGGKGLIGIATKEEDVVSQFFLANTHDNILFFTNTGKVFQTKGYDIPEASRQSKGKAIVNFLQVSPTD
MITAVIPISKEEKKGYLFMATANGVIKKVDLDAFAQVRRNGIAAIKLKGDDQLGWVLSTSGNDQIMLVSAEGNSIRFKEKDVRPMGRGAGGVIGIRLDKG
QKVVGADVIPSGLRILVVMANGYGKRTDLKFYKLQKRGGHGIKTAKITP-KTGNLVSAHIISENKDLIALSRKGQVIRTTVDSISVLGRATQGVRVMRLD
SGGLASVVVF--
>tr|A0A0G1MIT7|A0A0G1MIT7_9BACT DNA gyrase subunit A OS=Parcubacteria (Yanofskybacteria) bacterium GW2011_GWA2_44_9 GN=gyrA PE=3 SV=1
EEELVPEEDSLFMLTRGGYIKRMAPDDLRSQKRGGKGLIGMATKEEDVVSQFFMANTHDSLLFFTNSGKVFQTKAYEVPESSRQSKGKAIVNFLQVSPND
LITAVVPIPKDQKRMFLFMATKQGIIKKVDMDSFSQVRKSGMVAIKLKGNDELGWVLSTSGNDQVILVTSGGNAIRFKEKDVRPMGRSASGVIGVRLEKS
ESVVGADIVPSGLHILAVMENGYGKKTDLKFYKVQNRGGRGIMTAKITA-KTGNLVSAHVTQASMPSGAG------------------------------
------------
>tr|A0A0G1K1L8|A0A0G1K1L8_9BACT DNA gyrase subunit A OS=Parcubacteria (Yanofskybacteria) bacterium GW2011_GWA1_44_21 GN=gyrA PE=3 SV=1
EEELVPEEDSLFMLTRSGYIKRIQPDVLRAQKRGGKGLVGMATKEEDVVSQFFMANTHDNLLFFTNTGKVFQTKGYEVPESSRQAKGKAIVNFLNLSPSD
LITAVVPVPKNT-KGYLFMATAKGVIKKVEMDSFEKVRSNGIAAIKLKDDDQLGWVITTSGNDQIIMVSSGGNSIRFKEKDVRPMGRGASGVIGMRLDKD
EKVVGADAVPSGLKILVVMSNGYGKRTDLRFYKVQNRGGRGIMTAKITT-KTGKLVSAHIVSENKELVAVSQKGVVIRTSIESVSVLGRATQGVRVMKVE
SGHLASVALV--
>tr|A0A0G0P5X8|A0A0G0P5X8_9BACT DNA gyrase subunit A OS=Parcubacteria (Yanofskybacteria) bacterium GW2011_GWD2_39_48 GN=gyrA PE=3 SV=1
EEELIPEEDSLFMITHGGYIKRMAPDILRSQKRGGKGLMGMTTKDEDAVSHFFMANTHDSVLFFTNSGKVFQTKGYEVPEASRQSKGRAIVNFLQVSPTD
VITAVVPIPKES-KGFLFMATANGVIKKVDIDAFSSVRKSGMIAIKLKASDELKWVLTTSGNDQVMLVTSDGSAIRFKEKDVRPMGRSAGGVIGIRVDKD
SKVVGADVVPSGLKVLTVMENGYGKRTDVRFYKVQNRGGKGIMTSKITS-KTGNLVSGHITSENKELIAMSKKGQTIKTEISSVSILGRATQGVRIMRME
IGSIASTVVA--
>tr|A0A0G0QQP1|A0A0G0QQP1_9BACT DNA gyrase subunit A OS=Parcubacteria (Yanofskybacteria) bacterium GW2011_GWE2_40_11 GN=gyrA PE=3 SV=1
EDELVPEEDSLFIITHSGYIKRMVPDSLRTQKRGGKGTIGMATKDEDAVSQFFMANTHDSVLFFTNSGKVFQTKGYEVPEASRQSKGRAIANFLQVSPSD
VISAVVPVPKDT-KGFLFMTTAKGVIKKVDIDAFSAVRKSGMIAIKLKNEDQLNWVLTTSGNDQIILVTNSGNAIRFKEKDVRPMGRGASGVIGIRVEKG
EKVVGTDVIPAGLKLLAVMENGYGKRTDLRFYKVQNRGGRGIMTAKITP-KTGDLVSAHVTNENKELIAMSKKGQSIRTSIDSVSILGRATQGVRVMKLE
AGVVMSTVVA--
>tr|A0A0G1XJ96|A0A0G1XJ96_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWA1_49_11 GN=gyrA PE=3 SV=1
EEELIPEENSLFMITRDGYIKRMAPDLLKSQKRGGKGLVGMATKEEDVIAHFFLANTHDDILFFTNSGKVFQTKGYEVPESSRQSKGKAIANFLQVAASD
IITAVVKVPKNS-KGFLFMATANGVIKKVDMDAFAKVRSNGMAAIKLKGDDQLGWVITTSGSDQIVMVSSGGSAIRFNEKDVRAMGRAAGGVIGMRLDAK
EKVVGADVVPSGLKVLAVMSNGYGKRTELRYYKIQKRGGRGIMTANLTP-KTGNLVSAHVTSENKELIAVSRKGVVIRTDISTVSILGRATQGVRVMRIE
PGALASVVVV--
>tr|A0A0G0MQ44|A0A0G0MQ44_9BACT DNA gyrase subunit A OS=Parcubacteria (Yanofskybacteria) bacterium GW2011_GWA1_39_13 GN=gyrA PE=3 SV=1
EDELMPEEDSLFMITHSGYIKRMQPDGLKSQKRGGKGLIGMATKEEDVISQFFMANTHDSLLFFTNSGKVFQTKGYEVPESSRQSKGKAIVNFLNVSPSE
IITAVVPIPKEQKGGYLFMATANGVIKKVDADSFSQVRSNGMIAIKLKGNDELGWVLSTTGNDQVMLVTSGGNAIRFKEKDVRPMGRGASGVIGVRMDKD
EKVVGADVVPSGLKILVVMGNGYGKRTDLKFYKIQGRGGRGIMTAKITP-KTGKLVSAHITSENKELIAVSKKGVVIRTSIDSVSVLGRATQGVRVMRVE
AGGLASVVVV--
>tr|A0A0G1TP53|A0A0G1TP53_9BACT DNA topoisomerase (ATP-hydrolyzing) OS=Parcubacteria bacterium GW2011_GWA2_47_8b GN=UY12_C0033G0003 PE=4 SV=1
-----------------------------------------------ELTHFTAANTHDNVLFFTDRGRVFQTKVYEIPAGTRTSKGKPIHNFLEIPVEE
KISALITYEKTS-DGNLIMVTKKGLVKKTSLKGFDNVRRTGIIAIGLKKDDQLNWVRLSPGGDDVIITTALGQSIRFQEAKVRAMGRTAAGVRAIKLKGK
DQVASMDLIPKDSRLLVVMANGYGKQTPLSQYKTQGRGGSGIKTAAITA-KTGQLVAAAVLGA-EEVLALSTKGQIIRTQLATIRKASRATQGVRIMTLD
SGKVAGIVIL--
>tr|A0A0H5D7N1|A0A0H5D7N1_9PSEU DNA gyrase subunit A OS=Alloactinosynnema sp. L-07 GN=gyrA PE=3 SV=1
VEDLIAVEDVVVTITRTGYAKRTKTDLYRAQKRGGKGVQGAALKQDDIVAHFFVCSTHDWILFFTNKGRVYRAKAYELPEANRAARGQHVANLLAFQPDE
QIAQVIEIKDYTVAPYLVLATRDGLVKKSKLSDFDSNRAGGLIGINLREEDELVGAVLCSADDDLLLVSAGGQSIRFHASALRPMGRATSGVLGMRFNAG
DELLTLGVVR-DVFVLVATDGGYAKRTPIEDYSVQGRGGKGVLTIQHDS-RRGRLVGAVIVDIDDELYAITSAGGVIRTTAAEVRKAGRQTKGVRLMNLG
EGTLVAIARSA-
>tr|A0A0Q5VA96|A0A0Q5VA96_9ACTN DNA gyrase subunit A OS=Geodermatophilus sp. Leaf369 GN=ASG36_09385 PE=4 SV=1
MEDLIAEEQVVVTITRTGYAKRTKADLYRSQRRGGKGVMGATLKQDDLIQQFFVGSTHDWILFFTNKGRVYRAKAYELPEAARTARGAHVANILAFQPDE
KIAQVIQIKDYAVAPYLVLATANGQVKKTRLADFDSPRSGGVIAINLRDGDELVGASLIDPEQNLLLVTSRAMSICFKADQLRPMGRATEGVRGISLSDD
DRLLSMIVVT-GVDVLVATEGGYAKRTGIENYPEQNRGGKGVLTADPKS-RKGVLVGALSVVLGDELYAITSTGGVIRTPVNGVRHKDRATMGVKLMNLP
EDTIVAIARTT-
>tr|C0QRN3|C0QRN3_PERMH DNA topoisomerase (ATP-hydrolyzing) OS=Persephonella marina (strain DSM 14350 / EX-H1) GN=PERMA_1562 PE=4 SV=1
EAGLTFEEHYILAVLSSGRILNRRIDDDADKKDKVMNEVVSSVKPGEKLISVQEVESSIPIAFITDKGKAYWSLVADLPKGEGR---------INIDEGE
IVGTAF--K---GEDRLFILTKNGIIKRMSYEDIFY-KSQNHSIIPLAEDDCVVTAFADDHPSLIGVYTRKGDLLLFERNQVRVTGDKAKGVEAIDLDEG
DTVAGGFLINSEDLIMTVTKNGYTKLVRKEEFFVKKRAQKGLMAVKLGK-DDF-LSVAVPVELDETVYFSTEKGRVLKLIVKRIPVAKRTAMGDPVLKIE
-GYVVRAVKPK-
>tr|B2VA09|B2VA09_SULSY DNA topoisomerase (ATP-hydrolyzing) OS=Sulfurihydrogenibium sp. (strain YO3AOP1) GN=SYO3AOP1_1170 PE=4 SV=1
--ELTFKEHFMFAILNTGRIVNYKVEDETSKADRIINSLSISLTEGEKIVSIQEVEGSKPIAFFTKDGKAYWSLVIDLPKGEDK---------LNIE-GE
IVGTAY--Q---GENRVFLITKKGIIKRMSDEDIFY-KSQGHTVMPLNEGDELVVAVADRHPSYIGIYTKNADLLLFERNEVRITGDKAKGVEAIDLDEN
DEVAGAFFLNGHEYLLISTSFGYMKLVEKTEFPIKKRAQKGLLAVKLNK-DDY-VVSILPVNKSDEVLINTKHGKLLKLKIETIPVEKRTSLGKNLFKFE
-ARIVNVLKLP-
>tr|C1DW89|C1DW89_SULAA DNA topoisomerase (ATP-hydrolyzing) OS=Sulfurihydrogenibium azorense (strain Az-Fu1 / DSM 15241 / OCM 825) GN=gyrA PE=4 SV=1
--ELTFKEYFMFAIMSSGKVYNHKVDENTDKSEKIINDISLNSVEGKKIVSIQEVESSKPVAFFTKEGKADWSLVIDLPKGEGK---------LKID-SE
IVGTIY--Q---GENRVFLITKKGIIKRMFDEDIFY-KSHKHTVMPLNEGDELAVAIADQNPSYIGIYTKNADLLLFERNEVRVTGDKAKGVEGIDLDPN
DEVAGSFLIDGHNYILIATSKGYMKLVEKSEFPIKKRGQKGLMAVKLNK-DDY-VVSMIPVDIGEDVLVQTKHGKLLKIKVSIIPIGKRTSTGENKFNFE
-ASIVKVLKLP-
>tr|A0A0G0JFF4|A0A0G0JFF4_9BACT DNA topoisomerase (ATP-hydrolyzing) OS=Microgenomates (Daviesbacteria) bacterium GW2011_GWA2_38_24 GN=US86_C0005G0014 PE=4 SV=1
EEDLVADEVTIVTVTKNGYVKRQLPSTFRTQNRGGKGVSGITTKEEDAVSHIFYTKTLDNLLFFTDKGRVFQIKVWEIPESSRVAKGQAIVNLINIEQGE
KVTAMLTTRSTDKTKFLFMGTVNGTVKKTPIEEYANIRKNGLISIKLDSDDLLKWVVPTIGDDAIILVSKEGQSIRFSERDVKATHRDTSGVRGIKLGKG
DQVTSMNLASDTYELLVVMENGLGKKTKISAWKLQGRGGTGIKAAQVTS-KTGQIVAAEIVEYSNTLVLTSNKGQLIKLNIKDVPLLQRQTQGVILMRVK
TGKIVAGTIVS-
>tr|K2DAM6|K2DAM6_9BACT DNA gyrase subunit A OS=uncultured bacterium (gcode 4) GN=gyrA PE=3 SV=1
EEDLVADEVTIVTVTEGGYVKRQSPMSFRTQNRGGKGVSGITTKEEDAVSHIFYTKTLDNLLFFTDRGRAFQIKVWEIPEVSRIAKGQAIVNLINVEQGE
KVTAILTLRSKDTVKFLFMGTKMGNVKKTPVEEYANIRKNGLISIKLDSGDTLSWVVPTTGKDDMIIVSRKGQSIRFGEHLVRPTHRDTSGVRGISLSKT
DEVVSMNKVEDNSDLLVVMENGLGKKTKINAWKRQGRGGSGIKAAQVTD-KTGEIVTAEIIDKVDTLVMTSNKGQLIKLNLKDVPTLQRQTQGVILMRVR
AGKVAAATVVS-
>tr|I0L0A5|I0L0A5_9ACTN DNA topoisomerase (ATP-hydrolyzing) OS=Micromonospora lupini str. Lupac 08 GN=gyrA PE=4 SV=1
APLEVADDPCQVILSATGLVARTAAESEESAEG----RRRNGRVKHDTVRAIVHSTARGRVLLVTSAGRAFKIDVLPLPVLPEQAGGMSAAELVPLEAGE
TVVGLAPLGGAADSPGLALGTRQGVVKVCAPE--WPVRSDEFDVIGLRDGDEVVGATWTDGAETLTFVTSEASLLRFAAGMVRPQGPKGGGMAGINLPAG
ARVVFFGAVRTHGEPMVVTSTGTVKVTPFKAYPAKGRATGGVRAHRFLK-DETDVAVAWVGPR---PVGATGTGEPVELPA---ADPRRDGSGFAVML--
-GTVVGHLIER-
>tr|F4FH78|F4FH78_VERMA DNA topoisomerase (ATP-hydrolyzing) OS=Verrucosispora maris (strain AB-18-032) GN=VAB18032_13720 PE=4 SV=1
APLEVADDPCQVILSATGLVARTAAESEEAAEG----RRRHGRVKHDAVRAVVHSTARGRVLLVTSAGRAFKVDVLPLPVLPEQAGGMSAAELVPLEPGE
SVVGLAPLGPTAESPGLALGTRQGVVKVCAPD--WPVRSDEFEVIGLRDGDEVVGATWTDGAESLAFLTSAASLLRFPAGTVRPQGLKGGGMAGVALPDG
AQVVYFGAVRTHGEPMVVTSTGTVKVTPFAAYPAKGRATGGVRAQRFLK-GETDVVVAWIGPR---PVGSTANGEPVELPT---ADPRRDGSGFAVML--
-GTVIGHQIDR-
>tr|A0A0Q8ZMY9|A0A0Q8ZMY9_9MYCO DNA gyrase subunit A OS=Mycobacterium sp. Root265 GN=ASE48_10210 PE=4 SV=1
DEDLIAREEVVVTITETGYAKRTKSDLYRSQKRGGKGVQGAGLKQDDIVNHFFVCSTHDWILFFTTQGRVYRAKAYELPEASRTARGQHVANLLAFQPEE
RIAQVIQLKSYEDAPYLVLATRKGLVKKSRLTDFDSNRSGGIVAVNLRDDDELVGAVLCSAEEDLLLVSAKGQSIRFSATALRPMGRATSGVQGMRFNEE
DQLLSLNVVR-GTYLLVATSGGYAKRTAIEEYSAQGRGGKGILTVQYDP-KRGSLVGALIVDDETELYAITSGGGVIRTAARQVRKAGRQTKGVRLMNLG
EGTLIAIARNA-
>tr|H5SU06|H5SU06_9BACT DNA topoisomerase (ATP-hydrolyzing) OS=Candidatus Acetothermus autotrophicum GN=HGMM_OP4C642 PE=4 SV=1
EEALIPDTDLLISVSVKGYASAPKEEAYRKQQRGGKGILVMRLREGDAMKRVFACHARDDLLIFSKAHKAYKLKAYQLYSERRDVKGENLRNFIAMEPDE
EVCAMLPLHTDGTHRYCLMATAQGILNRNEYADFYNAHTSGILAINAEPGDYIVDAALSKGTGEVILASAQGMTIRFREELARCTGRPSKGVIGMRLDAG
DRLVGLVTLEPEDKLLLVTENGYGKRTPLEEFPSQGRGGKGVLGIKVDE-KTGPIVAIEKVKDDDEIMVTTLNGKIIRISAGEVRIVGRYAKGVKLIDLD
EGKVVSVVRYV-
>tr|C6WIH8|C6WIH8_ACTMD DNA topoisomerase (ATP-hydrolyzing) OS=Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971) GN=Amir_228
APLEVADDPCQVVLSATGLVARTAAESEEAVEG----RKRSGRAKHDAVAATVHTTARGQVLLVTSRGRAFKTDVLPLPVLPQGEGGVPVRELVGLEAGE
RVVGIAPLGET-DSPGLALGTKQGVVKVCAPE--WPVRSDEFEVIGLKAGDEVVGAQWADGQEALVFVSSEASLLRYAASLVRPQGLRGGGMAGITLPGE
ASVVFFGAVRTHGEPVVVTSTGSVKVTPFDLYPAKGRATGGVRAHRFLK-GEDGLVLAWVGAR---PAAVTESGAAVELPE---IDPRRDGSGAP-HP--
-GDVIGHLVER-
>tr|A0A0M8XZR9|A0A0M8XZR9_9PSEU DNA topoisomerase (ATP-hydrolyzing) OS=Saccharothrix sp. NRRL B-16348 GN=ADK67_42585 PE=4 SV=1
APLEVADDPCQVILSATGLVARTAAESEESSEA----RRRNGRIKHDAVAATVHTTARGQVLVVTNRGRAFKTDVLPLPVLPEQSGGMAASELVELEAGE
KVVGIAPLTDT-ESPGLALGTRSGTVKVCAPE--WPVRSDEFEVITLKEGDEVVGATWTSADETLVFVTSEASLLRYPASLVRPQGLRGGGMAGINVGSD
ARVVFFGAVRTHGEPMVVTSTGSVKVTPFAAYPAKGRATGGVRAHRFLK-GETALALAWVGPR---PAGAAQNGSPVELPA---SDERRDGSGHA-HP--
-GDVVGHLIER-
>tr|D3RUQ2|D3RUQ2_ALLVD DNA gyrase subunit A OS=Allochromatium vinosum (strain ATCC 17899 / DSM 180 / NBRC 103801 / NCIMB 10441 / D) GN=gyrA PE=3 SV=1
LEDLIAPEDRVVTLSHQGYVKTQPISDYQAQKRGGKGKSATAIKEEDFIDRIFVANSHDTVLCFSSRGRVYWLKVYELPQAGRGARGRPMVNLLPLEAGE
RITTLLPVRDY-EGSFVFMATSAGTVKKTPLKDFSRPLSRGIIAIDLREDELLVGATITGGEQDLMLFTSAGKAVRFSESHVRSMGRAAHGVRGVMLQEG
QRVIALVAPEDGGTVLSVTENGYGKRTDVDQFPTKGRGTQGVIAIDTAE-RNGAQVGAILVHPGDEIMLIADDGTLIRTSVDQIPVVGRNTKGVKLINLG
EGRLVFVERIA-
>tr|W0E165|W0E165_MARPU DNA gyrase subunit A OS=Marichromatium purpuratum 984 GN=gyrA PE=3 SV=1
LEDLIAPEDLVVTLSHQGYVKAQPLSDYQAQHRGGRGKSATSFREEDFIDRLFVANTHDTVLCFSSRGRVYWIKVYELPQGGRSARGRPMVNLLPLEQGE
RITAMLPVREY-EGYFVFMATSAGTVKKTPLRDFSRPLSRGIIAIDLHEDEYLVGVAITDGDQDLMLFTSAGKAVRFSEDQVRAMGRTAHGVRGVKLQPD
QRVISLVVPEP-GTVLSVTENGYGKRTTVDQFPTKGRGTQGVIAIRTSE-RNGEQVGAVLVLPGDEIMLITEHGTLIRTSVDEIPVVGRDAQGVKLINLG
DGRLAYVERVV-
>tr|G2DVZ1|G2DVZ1_9GAMM DNA gyrase subunit A OS=Thiorhodococcus drewsii AZ1 GN=gyrA PE=3 SV=1
LEDLIAPEEVVVTLSHQGYAKAQPISDYQAQRRGGRGKSATSFREEDFIDRIFVANSRDTVLCFSSRGRVYWLKVYEFPQAGRGARGRPMVNLLPLEADE
RINAMLPVRDY-EGYYVFMATSAGTVKKTPLQVFSRPLSRGIIAIDLRDDEYLIGVAITDGNQDLMLFTSAGKAVRFSEDQVRAMGRTAHGVRGVTLKEG
QEVISLVVPEP-GTVLSVTEHGYGKRTRIEEFPTKGRGTQGVIGISTSE-RNGAQVGAVLVRPGDEIMLITEGGTLIRTTVDEIPTVGRNAQGVKLINLA
EGRLVYVERIV-
>tr|I3YAQ3|I3YAQ3_THIV6 DNA gyrase subunit A OS=Thiocystis violascens (strain ATCC 17096 / DSM 198 / 6111) GN=gyrA PE=3 SV=1
LEDLITPEDVVVTLSHQGYVKAQPISDYQAQRRGGKGKSATSFREEDFIDRIFVANSLDTVLCFSSRGRVYWLKVYELPHSGRGARGRPMVNLLPLEPGE
RINALLPIREY-EGLFVFMATSAGTVKKTPLTDFSRPLSRGIIAIDLREDEVLVGVVITDGKRDLMLFTSNGKAVRFSEDHVRVMGRTAHGVRGVRLQDG
QRVISLLVPEP-GTVLSVTENGYGKRTRVEDFPTKGRGTQGVIGISTSE-RNGAQVGAVLVRPGDEIMLITEGGTLIRTTVDQIPVVGRSAQGVKLINLG
DGRLVYVERIV-
>tr|A0A0G1RCD5|A0A0G1RCD5_9BACT DNA topoisomerase (ATP-hydrolyzing) OS=Parcubacteria bacterium GW2011_GWA1_47_11 GN=UX77_C0024G0001 PE=4 SV=1
EEELIPEADSLFMITSDGYIKRMAPEAVRVQKRGGRGFLGMATKEEDMISQFFMANTHDTILFFTSSGKAFRTKGYEVPESSRQSKGKAIVNFLNISQEE
NITAVVPLSKEKKSGYLFMATTGGVVKKTDISEFENVRANGLIAIKLHPTDSLRWVQATTGKDEIIMTSSGGDAIRFKEKDVRPMGRSAAGVIGMRLDKG
ARIVSAEVIPADLKLLVVMKNGYGKRTELRHYKVQKRGGKGIKTAQITT-KTGEIISAHVVDPNKEIIAASQKGVVIRTMLDSVSNLGRATQGVRIMRLD
SGSIASVALV--
>tr|A0A0G1G084|A0A0G1G084_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWC1_43_12 GN=gyrA PE=3 SV=1
EEDLVAQEECMITLTQGGYVKRINPKNYRAQKRGGKGITGITTREEDSVDDMFCVNTHDNLLFFTTTGRVFQTKAYEIPEASRVARGQALVNFLQLGPNE
HVSSLVALKENIKENYLIMATKGGIIKKSPAEEFSNVRRSGLIAMNLTKGDELLWAKSTTGSDELMLVSAKGQSIRFKEKDVRPMGRTAAGVHAIKLKNG
DEVISMDVIRSKPMVLVVTENGFGKRTDLKQFKSQRRSGSGIKAAHVTP-KTGQIVSARILNGEQDLIAISEKGQVIRTTLGSVSVLGRSTQGVRIMKME
AGKVASIACI--
>tr|A0A0G1FVP0|A0A0G1FVP0_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWA2_43_9b GN=gyrA PE=3 SV=1
EEDLIAEEDCIITLTDGGYVKRMNPKNYKAQHRGGKGVSGITTREEDVVKYLACVNTHDNLLFFTNTGRVFQTKAYEIPEASRVARGQAMVNFLELGPKE
EVNALVAFKENLKENYLVMTTKDGIIKKTAIADFANVRRSGLIAIKLGKDDFLRWVKPSSGKDEIIMVTAKGQSVRFRESDARPMGRSAGGVRGLRLKKG
DAVVGMDIIKATQELLVVMENGYGKKTELKQFKIQRRGGSGIKAAQVTA-KTGQIVTAEILEDLEDIIAISKRGQVIRTSLGSISLLGRATQGVRIMKMD
EGKIASVTCL--
>tr|A0A0G1AMP7|A0A0G1AMP7_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWA2_42_11 GN=gyrA PE=3 SV=1
EEDLVPQEECIITLTSGGYVKRLNPKNYKAQHRGGKGIMGMTTREEDEVESMACVKTHDNLLFFTTTGRVFQIKGYEIPESSRVARGTAIVNFLQLGPNE
KVSALVATKEGLKEKYLVMMTKDGIIKKTDIAEFTNVRRSGLIAINLNKGDELRWVRVSSGQDEIILVTGGGQSIRFKEKDVRPMGRGAAGVRGLKLKKG
DEVINLDVIKSKPELLVVMQNGYGKKTDLRQFKIQRRSGSGIKAAQVTA-KTGQIVAAKILDPEQDLIAISQKGQVIRTALSSVSSLGRATQGVRIMKLE
PGKVASVTCL--
>tr|A0A0G0Q478|A0A0G0Q478_9BACT DNA topoisomerase (ATP-hydrolyzing) OS=Parcubacteria (Magasanikbacteria) bacterium GW2011_GWA2_40_10 GN=UT67_C0003G0033 PE=4 SV
TEDLIPNEATIIMVTSDGYIKRLPPDTFHQQSRGGKGVIGTATREEESVQNLVSTNTHDNMLFFTNRGRVFQLMAYDIPQGSRTAKGQALVNFLQLAPNE
KVTALLGMSDLTNIKYLVMTTTRGNIKKTNLEDFANVRRSGLIAIKLKNDDNLEWVKPTDGSAEIMVATKQGQAIRFKEKDVREMGRTAGGVRGIRLKGS
DEVIGMDIVDPSLAFLTVGENGVGKRTELDEYKVQGRGGSGIKTAEITA-KTLFRPGHPRCAPQRRWRQSGQRDFVVNSKFKII----------------
------------
>tr|A0A0G0KKY8|A0A0G0KKY8_9BACT DNA gyrase subunit A OS=Parcubacteria (Magasanikbacteria) bacterium GW2011_GWA2_37_8 GN=gyrA PE=3 SV=1
TEDLIPNEPTIIMTTTDGYIKRLPPDTFKQQSRGGKGVIGVTTKEEESVAELLTANTHDNILFFTNRGRVFQLMAYDLPQGSRTAKGQALVNFLQLAPNE
RVTALLSLADTAQTKFLVMVTTKGVIKKTALEDFANVRRSGLIALKLKLDDNLEWVKPTSGVSDVMIATKKGIAIRFKESNVRQMGRTASGVRGIRLHAN
DEVIGMDVVDTSLEFFTIGENGVGKRTPLAEYKTQGRGGSGIKTANVTE-KTGNIVQARVVDGDHDIVIMSTKGQVIRMPFKSIATSGRATQGTRLMRFK
DGKVVSVTIL--
>tr|F0S0B8|F0S0B8_DESTD DNA gyrase subunit A OS=Desulfurobacterium thermolithotrophum (strain DSM 11699 / BSA) GN=gyrA PE=3 SV=1
IESMIEEEEVVIFLTHKGFIARTSAKSYKTQGRSGTGVRGIRTREGDFVKDVITASSKDYLLIFTNQGKVYWLKAYEIPKTEKSTRGQSIRNFLPGMSGE
VVSRIIPVKDFSEKKDIFFVTQRGYVKRTSLSEFSNPRSTGINAINLEPGDRLIYVGLVEEKDNILLISKGGRAIRFHVQDVRQMGRSARGVKGMLLDEE
DRIMAGTVVQPDVYLLIVMEKGYGKRVLLSEFPLQRRGGKGLIAAKLSE-KTGKIADAITLKNEEPVIIVSRNGKIIRVNSSDVPVYSRYTRGVRIQKLS
KEVVVSVSKVQ-
>tr|A0A0F9RGQ3|A0A0F9RGQ3_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_0648450 PE=4 SV=1
KKDLVKKEPTMVILTKNHYIKRMSPQDYRTQRRGGRGKRGMTVNEEDFISDLFVCSTHDTILFFTSKGRVYTMKCFEVPLQQRTAKGRPIINLIKIREGE
EISSMIPINNF-DNDLLIMITKNGIAKKIQLKKFSKIPKSGLRAQSIRPNDMLVSVKMSNELQDIFIATKLGYAIRFDESELKEQRRTTMGYKGLSLREG
DEVIEGLLVNIDDIILTLSQKGYGQRTFVKEYRKTRRAAKGVKNIKLTK-ITQDKVIDVKISTEEDILVGTEQGQVIRVPIDSIRITHRPSKGVRVIKLY
ENSVTSIGKCE-
>tr|A0A0G1TLE3|A0A0G1TLE3_9BACT DNA topoisomerase (ATP-hydrolyzing) OS=Parcubacteria bacterium GW2011_GWA2_47_8 GN=UY09_C0009G0013 PE=4 SV=1
DTDLIPSEPTLLNITSQGYIKRLTPQTYRVQSRGGKGIIGAKLEKNDFITVFRVVNTHDSVYIFNEEGVVFTLKAYDFPDKKRDQKGEYLMDYVSWKAEN
FVAGAINVTGDKPPAYLFMVTKRGIIKKVAFDQFTNVSKGGLIAMRLKEGDHLMATMALYQDEDILLVSKLGKAIHIQSGAVSALGRQAQGVRGMRLGSG
DEVAGMIRITPKAHVLTMSVNGYGKRTEIRQFAIQNRGGKGLIASKVTA-KTGAVRAVQLVTPYSDFMVITKQGKVLRGSLKQISTLGRATQGVRIIKLD
EGELRSLNLMK-
>tr|K2FNP0|K2FNP0_9BACT DNA gyrase subunit A OS=uncultured bacterium (gcode 4) GN=gyrA PE=3 SV=1
EEDLVAKEETLITVTKTGYVKRLSAGAYRAQRRGGKGVIGMTTKEEDEIEHLVDATTHDTILFFTNKGRVFGIKAWEIPESSRQAKGQALVNLLNLEQGE
EIRSILPMAKDSEIKNLIMATKTGLIKKTKISEFENLRASGLIAIKLRNEDQLVSVHPTTGEDHIILLTKGAKSIKFPEANVRPMGRATTGVTGIRLDKE
DELIGMEVFPAFRDILTIAEKGLGKRTPVHLFPVQKRAGKGVKAAVVTD-KTGSLKTAIMVTQIDQVVITSRMGQVIKLPLKNIPQLGRATQGVILMRFA
KASVAAAAVLE-
>tr|A0A0G0WQ70|A0A0G0WQ70_9BACT DNA gyrase subunit A OS=Microgenomates (Woesebacteria) bacterium GW2011_GWB1_41_10 GN=gyrA PE=3 SV=1
EEDLVAKEETLITVTKTGYIKRLSSTSYRAQRRGGKGVIGMATKEEDEIEHILSATTHDTILFFTNKGRVFGTKAWEIPESSRQAKGQALVNFLNLDQGE
EIKSILPLSKDSGIKNLIMATKLGIIKKTNINEFENLRASGLIAIKLRGEDQLISVHPTSGEDHIILLARGGKSIRFPEVNVRSMGRATTGVAGIKLETQ
DELIGMDVFPGFRDILTIAEKGLGKRTPIHFFPIQKRAGKGVKAAVVNP-KTGNLKTASMVTRIDQIIITSKMGQVIKLPLKNIPQLGRATQGVILMRFA
KGSVAAAAVLE-
>tr|A0A0G0X7C4|A0A0G0X7C4_9BACT DNA gyrase subunit A OS=Microgenomates (Woesebacteria) bacterium GW2011_GWA1_41_13b GN=gyrA PE=3 SV=1
EEDLVAKEETLITVTKTGYVKRLSATSYRAQRRGGKGVIGMATKEEDEIEHILSATTHDTILFFTNKGRVFGLKAWEIPESSRQAKGQALVNLLNLEQGE
EIKSILPLSKELGIKNLVMATKNGLIKKTGIDEFENLRSSGLIAIKLRDNDMLISVHPTTGDDHIILLTRNAKSIRFPETNARPMGRATTGVTGIKMDTG
DELIGMEVFPAYRDILTIAEHGLGKRTPIHLFPVQKRSGKGVKAAVVSA-KIGNLKTAAMVTEYDQVIITSKMGQVIKLPLKNIPQLGRATQGVILMRFA
KGSVAAAAVLE-
>tr|A0A0G1G7T8|A0A0G1G7T8_9BACT DNA gyrase subunit A OS=Microgenomates bacterium GW2011_GWC1_43_13 GN=gyrA PE=3 SV=1
EEDLVAKEETLITVTRTGYIKRLSAGSYRAQRRGGKGVIGMATKEEDEIQHLIDATTHDTILFFTNKGRVFGLKAWEIPESSRQAKGQALVNLLNLEQEE
EIRSILPLSKESGVKNLIMSTKRGLIKKTNLDEFENLRSSGLIAIKLRSDDQLVSVHPTSGSDHIIILTKGAKSIRFPELNVRPMGRATTGVTGIKMEKD
DEVIGMEVFPGFRDILTIAEKGLGKRTPIHLFPVQKRAGKGVKASVVNP-KTGNLKTAIMVTQFDQVIITSKMGQVIKLPLKNIPQLGRATQGVILMRFA
KASVAAAAVLE-
>tr|A0A0G0KMV8|A0A0G0KMV8_9BACT DNA gyrase subunit A OS=Microgenomates (Daviesbacteria) bacterium GW2011_GWF2_38_6 GN=gyrA PE=3 SV=1
EEDFIKDENVAITITHSGYIKRLPIEVYKTQHRGGKGVIAATIKEEDIINDIFTANTHDYLLFFTNKGKIYWLKVHQIPEAARTAKGKAIVNLLALENEE
KISAYVPVRNF-DSHFIIMATKKGTVKKTSLDSFSNPRRTGIIAITLEDKDELINVELTDGNQEIIIATKSGNAVRFNEKNVRGSGRSSQGVRGISLKGD
DEVVGMIVASNEKTLFTVTENGYGKRTPIEDYRLINRGGSGVINIQCSE-RNGNVVAICDVDENDDIMLISKNGIVIRVPASDISVIGRNTQGVRIMKME
EGKAVSAVKVA-
>tr|A0A0B3APB3|A0A0B3APB3_9ARCH DNA gyrase subunit A OS=archaeon GW2011_AR11 GN=gyrA PE=3 SV=1
MEDLIEEGNTVITVTKSGYIKRLPLATYKQQHRGGKGVIATTTREEDIVADIFIAHTHATLLCFTNRGRMHWLKTYAIPEASRQAKGKAIVNLLSLEQGE
HVTTFIPVREF-DKHHLIMATRNGTIKKTNLIAYSNQRKTGIIAITLDEGDRLMDVKLTDGKQDVLLATAQGMAVRFAEEDVRPTGRSSQGVRGITLKRD
DKVIGMIVAEKNKDILTITSNGYGKRTPIKLYRHISRGGSGVKDIQTED-RNGPVASVTCVSDNDEIMVITKSGITIRTPVSGISIIGRNTQGVRIMRLE
QGEIVSVTRVE-
>tr|A0A010ZK08|A0A010ZK08_9ACTN DNA gyrase subunit A OS=Cryptosporangium arvum DSM 44712 GN=gyrA PE=3 SV=1
MEDLIAEEPVVVTITRTGYAKRTKVDLYRSQRRGGKGVQGAALKQDDIVAHFFVCSTHDWILFFTNKGRVYRVKAYELPEASRTARGQHVANLLAFQPDE
QIAEVIEIRTYEDAPHLVLATRNGLVKKTKLTEFDSNRQGGVIAINLREEDELVGAELINENDNLLLISKQAQAICFKADTLRPMGRATSGVIGMRFSGE
DELLSMHVAR-GMDVLVATEGGFAKRTPIEEYPVQGRGGKGVVTARIVT-KRGRLIAALAVTTDDELFAITSNGGVIRTPVRQVRRRDRNTMGVKLMELP
AGTLVAIARNE-
>tr|D3PTX2|D3PTX2_STANL DNA gyrase subunit A OS=Stackebrandtia nassauensis (strain DSM 44728 / NRRL B-16338 / NBRC 102104 / LLR-40K-21) GN=gyrA PE=3 SV
MEDLIAREDVVVTITRGGYAKRTKVDLYRSQRRGGKGVSGATLKQDDLVSHFFVCSTHDWMLFFTNKGRVYRAKAYELPEASRTARGQHVANLLAFQPDE
QIAQVMQISGYDVAPYLVLATRRGLVKKTKLTDFDSPRTGGVIGINLRDGDEVVGAALINPDDDLLLVSKKAQAIRFMASSLRPMGRATSGVIGMRFVEA
DELLTMEVVR-GMDILVATSGGYAKRTPVEEYPQQGRGGKGVLTAKITE-RRGNLVGALSVTPDDELFAITSEGGVIRTPVKPVRRTDRNTMGVKLMDLP
EGSLLAMARSA-
>tr|R4LCK0|R4LCK0_9ACTN DNA gyrase subunit A OS=Actinoplanes sp. N902-109 GN=gyrA PE=3 SV=1
MEDLIAREDVVVTITRTGYAKRTKVDLYRSQKRGGKGVSGATLRQDDIVSHFFVISTHSWILFFTNKGRVYRAKAYELPEAARTAKGQHVANLLAFQPDE
HIAQVIQIPHYEVEPYLVLATKNGLVKKTRLAEFDSNRSGGIIAINLREDDELVGAALAASENDLLLVSKHAQAIRFNATALRPMGRATSGVIGMRFSGD
DELLAMEVVR-GLDVLVATNGGYAKRTPIEEYPVQGRGGKGVLTAKITE-RRGGLVGALVIDPEDELFAITSNGGVIRTPVKPVRRRDRNTMGVKLMDLP
EGTIVALARNA-
>tr|A0A0M2RLI3|A0A0M2RLI3_9ACTN DNA gyrase subunit A OS=Micromonospora sp. HK10 GN=gyrA PE=3 SV=1
MEDLIAREDVVVTITRTGYAKRTKVDLYRSQRRGGKGVSGATLRQDDIVSHFFVCSTHDWILFFTNKGRVYRAKAYELPEASRVAKGQHVANLLAFQADE
QIAQIIEIPNYQVAPYLVLATKNGLVKKTRLEEFDSNRSGGIIAINLRDEDELVGAALVGPEDDLLLVSKNAQAIRFGATTLRPMGRATSGVIGMRFSEE
DVLLAMEVIHREKDVLVATNGGYAKRTPIEEYPVQGRGGKGVLTAKITE-RRGGLVGAVVISPDDELFAITSNGGVIRTPVKPVRRRDRNTMGVKLMDLP
DGTIVAIARNA-
>tr|A0A098BMN6|A0A098BMN6_9NOCA DNA gyrase subunit A OS=Rhodococcus ruber GN=gyrA PE=3 SV=1
DEDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVKGADLKQDDIVKHFFVTSTHDWLLFFTTKGRVYRAKAYELPEANRTARGQHVANLLAFQPDE
RIQGVIRLKSYEDAPYLVLATRNGLVKKSRLSDFDSNRSGGIVAINLRGDDELVGAVLCSSDDDLLLVSAKGQSIRFVASVLRPMGRATSGVQGMRFNED
DALLSLNVVR-GTYLLVATSGGYAKRTPIEDYMAQGRGGKGVLTIQYDR-KRGTLVGALIVDDDDELYAITSGGGVIRTPAKQVRKAGRQTKGVRLMNLG
EGTLLAIARNA-
>tr|D8LPZ0|D8LPZ0_ECTSI DNA gyrase subunit A OS=Ectocarpus siliculosus GN=Esi_0056_0068 PE=4 SV=1
EEDLLANDNSVVVVTAAGYIKRMPLEEFTAQNRGTRGKAGAKSSDHDVVQHFFTCQDHDTILFVSDKGVAYGIRAFQVPVGSRTAKGVPVPQVLPIAGDE
QIASVLAVDDFREDEYLVLLTQKGYIKRTPLAAFKSTSSRGLIIISLGEDDTLRWVKRCCDENGIVIGSKQGYATRFLAKDLRPSGRTSRGVKE------
----------EGHSLLVLTTRGYGKRVALNEFKTTRRGGKGVIALKLRQKLEDTLACFRIVGADDEIMLSTAQGTIVRQRAGAIARQSRTATGVIVQKLD
ANGIKDVALVPE
>tr|W7TLA9|W7TLA9_9STRA Dna gyrase subunit a OS=Nannochloropsis gaditana GN=Naga_100020g46 PE=3 SV=1
ELDLLANDRSVMMVTEAGYIKRMPLDDFEQQRRGTRGKAGARMSQDDLVNHFFACNDHDHVVFISEKGVAFGIRAFQVPVASRVSKGVPLPQVLPLSSDD
HVSSVIPLGEFQADEFLVLLTKQGFIKKTPVDAFKKLTSRGLIAISLGEGDTLGWARRCTDQDDILISTRKGYSMRFASADLKPTGRTSRGCSAIKLRKT
DEPGDCGSGSNGQYLLAVTTAGYGKRVSADSFKVQRRGGMGVIAIKFKAGG-DSLACMRACSDDYEVVLSTQKGTIVRQRVAAIALQSRTATGVRVQRLD
EGIIKSVAMLPA
>tr|Q0IBI6|Q0IBI6_SYNS3 DNA gyrase subunit A OS=Synechococcus sp. (strain CC9311) GN=gyrA-2 PE=3 SV=1
DIDLIANERSVVLLTETGYLKRMPVSEFEATSRGTRGKAGTRSQGEEAVKLFIGCNDHDTLLLFSDRGVSYAVPAYRVPQCSRTAKGTPIVQLLPIPREE
AITSLLAVSEFNDDTDLLMLTTGGYIKRTRLSAFSNIRSNGLIAIGLEEGDALTWVRLAVPGDSVLIGSRAGMTIHFRLNELRPLGRTARGVRSMNLREG
DSDGGESAAAEGPWVLVASASGLGKRVPVTQFRLQKRAGMGLRAMKFRTD-ADELVGLRVLGAGEELLLVSEKGVIVRTGADAIPQQSRAATGVRLQRLD
KGRLADVVLVPP
>tr|A2C856|A2C856_PROM3 DNA gyrase subunit A OS=Prochlorococcus marinus (strain MIT 9303) GN=gyrA PE=3 SV=1
DIDLIANERSVVLLTETGYLKRMPVSEFEATSRGTRGKAGTRSQGEEAVKLFISCNDHDTLLLFSDRGVSYALPAYRVPQCSRTAKGTPVVQLLPIPREE
AITSLLSVISFDDDTHLLMLTKGGFIKRTSLSAFSKIRSNGLIAIGLEEGDALTWVRLAVPGDSVLIASRAGMTIHFRLEELRPLGRTARGVRAMNLRGG
DSSVETVVVSDGPWVLVASASGLGKRVPVNQFRLQKRAGMGLRAIKFRRE-GDELVGLRVLGYGEELLLVSERGVIVRTSADKIPQQSRAATGVRLQRLD
AGRLSEVVLVPP
>tr|I4HVZ5|I4HVZ5_MICAE DNA gyrase subunit A OS=Microcystis aeruginosa PCC 9809 GN=gyrA PE=3 SV=1
ETDLIANEQALILVTEQGYIKRMPVNTFESQNRATRGKAGAKMKEDDGIDHFITCRDHDSVLFFTDRGVVYSLNAYHIPTGSRTARGVPIVQLLEIPKGE
KITSVVAVSEFSEDNYLIMLTQKGFIKKTALAAFSNIRSNGLIAISLEDGDQLRWVRLAKEEDSVIIGSRQGMAIHFKAQQLRSLGRATKGVKSMKLRSG
DEEINPEVANNGPWVLAITMAGLGKRVPVTLLRLQNRAGLGVRVIKFRKK-NDKLAALHVVNPHEEFMIITERGIIIRQSVDAITPQSRSAGGIRVQKLD
EDAIAAVALVPP
>tr|A6W3W0|A6W3W0_KINRD DNA gyrase subunit A OS=Kineococcus radiotolerans (strain ATCC BAA-149 / DSM 14245 / SRS30216) GN=gyrA PE=3 SV=1
VEDLIPVEDVVVTVTRGGYAKRTKTDLYRAQRRGGRGVRGASLREDDVVEHFFTTTTHHWLLFFTNLGRVYRAKGYELPEGGRDGRGQHVANLLAFQPGE
RIVAVLDIEDYEQAPYLVLATRGGIVKKTRLSEYDSNRSGGLIAINLRSDDELFAATLVSEDEDLFLVSRKGMSVRFEAENLRPMGRATSGVTGMKFRGE
DELLAMAVARDDLFVFVVTELGYAKRTKIEHYRKQGRGGLGIKVAKLTEE-RGDLVGALTVSEDDEVLVVMQAGRVVRSRVDEVPDKGRDTMGVTFARPE
TGRILAITRNVE
>tr|A0A0L7RSN7|A0A0L7RSN7_9RHIZ DNA gyrase subunit A OS=Shinella sp. GWS1 GN=gyrA PE=3 SV=1
DEDLIAREDMVVTVSHAGYVKRVPLATYRAQRRGGKGRSGMAMKDEDFATRLFVANTHTPVLFFSSRGIVYKEKVWRLPIGTPQSKGKALINMLPLTPGE
RITTIMPLPETWENLDVMFATTRGTVRRNKLSDFVQVNRNGKIAMKLEEGDEILNVETCTEHDDVLMTTALGQCIRFPVVRV-FAGRNSVGVRGISLGGG
DRERYQELRSREQFVLTVSQKGFGKRSSSYDFRTSGRGGKGIRATDTSKTEIGELVAAFPVEEKDQLMLVSDGGQLIRVPVDGIRIASRATKGVTIFSTA
KDKVVSVERISE
>tr|A0A081MI90|A0A081MI90_9RHIZ DNA gyrase subunit A OS=Rhizobium sp. R1-200B4 GN=gyrA PE=3 SV=1
DEDLIAREDMVVTVSHLGYIKRVPLTTYRAQRRGGKGRSGMATRDEDFVTRLFVANTHTPVLFFSSRGIVYKEKVWRLPVGTPTSRGKALINMLPLEPGE
RITTIMPLPESWENLDVMFSTTRGTVRRNKLSDFVQVNRNGKIAMKLEDGDEILSVETCTDRDDVLLTTALGQCIRFPVVRV-FAGRNSIGVRGITLQPA
DRERYQELKTREQFVLTVSEKGYGKRSSSYDFRTSGRGGKGIRATDTSRTEIGELVAAFPIEDTDQIMLVSNGGVLIRVPVNGIRIASRATKGVTIFSTA
KDKVVSVERISE
>tr|K0SED5|K0SED5_THAOC Uncharacterized protein OS=Thalassiosira oceanica GN=THAOC_16005 PE=4 SV=1
EIDLVQNERSVIVVTRGGYIKRMPLKTFGSQGRGTRGKRGTSLSDDNEIAHCFSCNDHDTVLMTTQSGIAYGLRGYQVPEGGRTARGAPIPSVLPIKAGD
VITSVLPVSEFSKDQFIVLATKNGWIKKTSLKAFENLTSRGLIIASLGEGDRLNWCERCTNKDDILVGSTRGQATRFAAADLRATGRTSRGVKALTLKKG
DTDVNILDGMGDEALLIVTMEGQGMYELLGP--------ASWI-----------------FRDFNSRPSSLQQGVIVRQNVKDIPIQGRTATGVLVQKVD
SGHISTVSIVPK
>tr|B5Y5U7|B5Y5U7_PHATC Predicted protein OS=Phaeodactylum tricornutum (strain CCAP 1055/1) GN=PHATR_33633 PE=4 SV=1
DMDLIENSRSVIVVTRGGYIKRMPLKTFESQGRGTRGKRGTSESADSEVAHCFTCNDHDTLLMVTQNGIAYGLRAYQVPIAGRTAKGQPIPSVLPVRGDE
VITAILPVSEFSDEEYVVLTTEQGWIKRTPLDAFEKLSSRGLTIATLEDGDRLKWCHRVRNEDDILIGTVGGMATRFGAAKLRPTGRTSRGVRAMKLREG
DTDMNVLSGKNKEYILTVTAQGYGKRIATSEFRAQARGGVGVIAIKFKRGEEDKVSCLRIVKDDEEILVITARGIMVRQKASDIPSQGRSATGVMVQRVD
DGHISSVSIVPQ
>tr|B8BXG7|B8BXG7_THAPS DNA topoisomerase IV, ATP/GTP binding site OS=Thalassiosira pseudonana GN=DNA_TopoIV PE=4 SV=1
DIDLVQNERSVIVVTRGGYIKRMPLKTFESQNRGTRGKRGTSISDDNAVAHCFTCNDHDTVLMTTQSGVAYGLRAYQVPEGGRTARGAPIPSVLPVKSDD
VITSVLPVSEFSKNEFIVLATEYGWIKKTPLAAFEKLTQRGLIIATLADGDRLNWCEKCTDNDDILVGSTRGQATRFKAADLRPTARTSRGVKSMTLKKG
DTDMNVLRKEDK-FVLVVTTEGYGKRVLTEEFRTTARGGSGVIAIKFKAGVDDRISTMRVVNEDDEILLITSQGVIVRQKVSDISCQGRAATGVLVQKVD
SGSISTVSIVPK
>tr|A0A0G1HZE1|A0A0G1HZE1_9BACT Gyrase subunit A protein (Fragment) OS=bacterium GW2011_GWA1_44_22 GN=VE96_C0018G0001 PE=4 SV=1
EKDLVPNEEVIITMSKGGYIKRQPVAAYRSQNRGGKGIIGMTTKEEDQIEIIQSSKNHDDILFFTNRGRVFRQKVYEIPQSSRIAKGTAIVNVIQLAPEE
IVTALLTMPSYKPGDNFVMVTRRGVIKKTVAEKYANIRTNGLIAIKLDQGDELKWVHKSRKGNSVVIMTKEGQSIHFAESDARLLGRSTRGVRGIKLREH
DEVISAAVADPDTEYVVISERGFGKRTHLNQYSLQHRGGIGVKTMNLTT-KTGKLIGGRLVEKPADIIITSVQGQVIRTPLHKISLLGRVTQGVTIMRLK
NSKVASLSIITK
>tr|K1YBZ5|K1YBZ5_9BACT DNA gyrase, A subunit (Fragment) OS=uncultured bacterium (gcode 4) GN=gyrA PE=4 SV=1
PKDTIPNEEVVITLSKNSYVKRIKSSSFRTQRRGGKGVN-VAVKDEDEVKIILSTSNHSDLLFFTNTGRVFSLPAYEIPETQRTAKGQPIINLLSLQKDE
DITAILDLAA-VTGKHFALISKKAVIKRVDMEDVKNIRTSGLIVMKPREGDELGWVRVTNGEDNILMVSKHGKAIQFKEEDIRVMGRGAAGVRGMRIAEN
DSVVEADVVSENDKYVTVTENGMGKITNIEEYREQGRGGSGVKVGAMTE-KTGDVIGVSLLSERGEVMLISKTGQTVRVPLNGVRTTSRVTQGVILAKLK
DKDSFTTATMKK
>tr|X0TAJ8|X0TAJ8_9ZZZZ Uncharacterized protein (Fragment) OS=marine sediment metagenome GN=S01H1_07128 PE=4 SV=1
AEDLIPDETVLISISRRGYIKRTPAKAYRSRAGRGRGIAGMSIRAEDAVQHLFAANSLAGVLFFSNRGKVFQEKVYQIPDAQRQARGIPLGNLLTLSRGE
RITAALPVPSFEETAFLTMVTRQGRIKRVALGELASVRRSGLVAIKLEKGDELGWVRLTNGDQEIILVTKRGKALRFSETAVRPQGRAGAGVWAIRLAGG
DAVTSVDVVEPEGQLLVMTAHGYGKRTSLSEFPTKGRHGGGMVTLHQLS-QTGPIVAARVVGL-SEVTIITAEGMALRTHVENFPQQGRASRGKRVIDLE
AGVVASVARAEK
>tr|A0A0G1S3Q8|A0A0G1S3Q8_9BACT DNA gyrase subunit A OS=Microgenomates bacterium GW2011_GWF2_46_18 GN=gyrA PE=3 SV=1
EEDLVASVDNLVVITREGYIKRMPLNSYRTQRRGGKGVVGMTTKDEDEVLHMTVANTHDYCLFFTDLGKVYAIRAFELPEGSRQAKGQAIINLLSIEQDE
KVQALLTLTKADQSHFVTMATQKGMVKKTPLAEYESIRTSGKIGISLRDNDKLVKVVLSNGQNYIVLITALGKSIKFKETDVTATGRDTMGVKGMTLKPE
DKVLTMETVEIFREILVVTEHGLGKRTNVEEYPEQKRGGQGVKVAELSD-KTGQVAAIRLVTEDEQVVITTKAAQVIKLPLKNIKVLGRSTQGVILMRPH
PGVVTSVTTL--
>tr|A0A0G1NZN4|A0A0G1NZN4_9BACT DNA gyrase subunit A OS=Microgenomates bacterium GW2011_GWA2_46_16 GN=gyrA PE=3 SV=1
EEDLVAAEDNLVAITRDGYVKRMPLSTYRTQRRGGKGVVGMTTKDTDEILHMTVGNTHDFALFFTNTGKVYSMRVFELPEGSRAAKGQAIINLLNIEQGE
MVQAVLTVNKDDKGHFITMATKNGMIKKTPLSQYESIRQSGKIGISLRDGDQLIKVEISHGQNYLILVTRGGKSIKFKETDVTATGRNTMGVKGITLKNG
DAVIAMETVEIFREILVVTEHGLGKRTDVGEYPEQKRGGQGVKVAELSP-RTGDIASVRMVTEDEQVVITTKAAQVIKLPLKNIKVLGRSTQGVILMRP-
------------
>tr|A0A0G0U9A0|A0A0G0U9A0_9BACT DNA gyrase subunit A OS=Microgenomates (Daviesbacteria) bacterium GW2011_GWA2_40_9 GN=gyrA PE=3 SV=1
EEDLIADEPTIVTITDGGYIKRQAPSTFRVQARGGKGVSGITTKEADAVSHIFHTMTLDNILFFTDKGRVFQLKVWEIPETSRIAKGQAVVNLINIDQGE
KITAILTLRQKDTARYLFMCTKQGNVKKTETSQYASIRRNGLISINLDSGDTLGWVVPTNGENELIIVSKLGQSIRFTEKNVRPTHRDTSGVRGVRLSKD
DSVVSLNKVSDGDQLLVVMANGLGKKTLISSWNKQGRGGMGVKAAQVTN-KTGPIVTAQIMDKGDTLVLTSNKGQLIKINIKDVPTLQRQTQGVILMRMR
EGRVVAATIV--
>tr|A0A0G0QLK3|A0A0G0QLK3_9BACT DNA gyrase subunit A OS=Microgenomates (Daviesbacteria) bacterium GW2011_GWC2_40_12 GN=gyrA PE=3 SV=1
EEDLVPNEVTIATITEGGYIKRQSPHSFRTQGRGGKGVMGISTKETDAVSHIFYTQTHDNILFFTDKGRVFQIKVWEIPETQRTAKGQAVVNLINVEQGE
KITAVLTTRQKESAKYFFMCTKKGTVKKTSLEEYANIRKNGLTAIKLDSGDELGWVAATGGKDDLIIVSKDGKSIRFTEAQVKPTHRDTSGVRGIRLTGK
DEVVSLNTVQSEETLLVIMENGLGKKTKFSAWSRQGRGGQGVKAAQVTA-KTGPIVTAQALNEMDTLVMTSTKGQLIKMNLAEVPTLQRQTQGVILMRVR
PGKVAAATVV--
>tr|A0A0G1B7T5|A0A0G1B7T5_9BACT DNA topoisomerase (ATP-hydrolyzing) (Fragment) OS=Microgenomates (Daviesbacteria) bacterium GW2011_GWA2_42_7 GN=UV41_C0057G0001
EEDLIADEATIVTITENGYIKRQQPGTFRMQNRGGKGVSGITTKEEDAVAHIFYTKTLDNILFFTDKGRVFQLKVWEIPEASRIAKGQAIVNLINTEQGE
KITAILTIRKKDPAKYLFMCTWQGNIKKTLIEEYASIRKNGLISIKLDSGDTLGWVMPTSGEDDLIIVSQGGQSIRFAEKDVRPTHRDTSGVRGIKLGKG
DSVVSLNKITDTDQLLVVMANGLGKKTLVSGWSKQGRGGMGVKAAQVTP-KTGPIVTAKLASKSNTLVMTSNKGQLIKLDLKDVPTLQRQTQGVILMRMR
EGNVVAATLV--
>tr|C5UPX9|C5UPX9_CLOBO DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium botulinum E1 str. 'BoNT E Beluga' GN=CLO_3018 PE=4 SV=1
IEELIIVEEVMITLSKDGFIKRIPVKNYI---RSNSNPEDIEYREGDKLEYLISSNTRDSLLIFTDKGFMYQVKGINIPELKWKEKGERLDTIIKSLNDE
KIVEVISVDNFNPNKIFRFITKSGGIKESSLDKFET-SYGKLQALKLRDKDALLNVKLRDREEYLNIKTKLDLEFTIEVPELENVPRNILPIQLFNLSID
DEIIEVNESKENLALYSFSKKGLVKKTLLNEFKLDTQKQFFYKLKT----EDDEVISVDINNTLGNLIIITKKGMAIRFPVENVNSMGKVASGVTGISLR
EEEVIFGAYV--
>tr|D9SPV6|D9SPV6_CLOC7 DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium cellulovorans (strain ATCC 35296 / DSM 3052 / OCM 3 / 743B) GN=Clocel_2376 P
MDELIVVEDIVITLSNEGYIKRVPQKTYV---RSNSNPQDIEYREGDYNRFIISSNTLETILVFTDNGNMYQFKGNAIPELRWKEKGERLDTIIKGMNSE
RIVTALSIKDFSGPFNVQFITNKGIIKKTSLSKFAS-SYTKLMAIKLKEDQKLVSVEIFDCERFVQILTSQGLTFTVNEPKLDDSDRMIQGTMLATIPAK
DSIEKAEYIEIDSYIIFFSKRGYVKKTSLKEYQGEYLCSQGYKLKN----DSDELVGA-SLIEAENFVLVTQKGMAIRVNCNDVNEMGKIASGVIGISLK
DEFVIYGNTI--
>tr|A0A0H3J1N5|A0A0H3J1N5_CLOPA DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium pasteurianum DSM 525 = ATCC 6013 GN=gyrA2 PE=4 SV=1
LEDLIIVEDTVVTLSKEGYIKRIAQKTYA---RSNTNVEDIEYREGDCNRFLFNSNTTHTIMFFTDQGNMYQLKGISVPEYKWKEKGEKLDSIIRGLNKE
NIINVFSIENINSQKDMIFITDRGYIKKTALHKFDS-NYSKIMALKMKGNEKLIFAELVDKSRFLKIETELNFKFTIEEPVIEESERNSLGNKLFNLSDK
DSIISVHFSNENIDTYFFTGNGLIKKTALEDFKTENSSTVVYKFRG----DDI-LVNVEFMDKDNDIIIITLKGMGIRFSSQNISHMGRIASGVTGISLE
EEEVLKGFLC--
>tr|R6KG09|R6KG09_9CLOT DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium sp. CAG:265 GN=BN573_00479 PE=4 SV=1
VEELIVVEDVMITLSKDGFIKRLPVRSYT---RSNSNADDIDYRDGDELKYLFKSNTAENVIVFTDKGNMYQTKGINIPEFKWKEKGERIDSIIKALDEE
TIISAMSINIFDAERSFLFITNKGTIKKSTLDKFVT-NYSKLQALKLRENEFVVNCVLVDSEFFLEVKSKLGLEFKLQVPVIEDMQRNVLGQQLFNLTAD
DEVVEVAYTNEEKMLYFFTKKGMVKKTALSEYGGEYLVQQGYKFKY----ENDEIIAVRMADVLSDVIIVTKGGMAIKFSSENVNSMGRIASGVTGISLR
DGEVISADVK--
>tr|A0A0F3FM12|A0A0F3FM12_9CLOT DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium baratii GN=UC77_12745 PE=4 SV=1
VEELIVIEDVMVTLSKDGFIKRIPHKNYI---RSNQDVEAIDYREGDELKFLFESNTRDNILIFTDKGNMYQTKGINIPEGKWKDKGERIDTLIKTLDEE
TIVNVISETTLNPNKYIQFITSKGMIKKSSLDKFKT-SYSKLQAIKLKDNENVVSVILLNGEEFLKVKTKIGLEFNLEIGEVLDTPRNIMGSYLFNLSDN
DEVISCEYVDTDLAVFVITKRGLVKKTMLTEFSHDFTITQYYKFKF----DDDEIASITINNKYGELVIITKKGMAIRFNQSNINPMGRIASGVTGISLK
DNEVLYGRYI--
>tr|A6TSS8|A6TSS8_ALKMQ DNA topoisomerase (ATP-hydrolyzing) OS=Alkaliphilus metalliredigens (strain QYMF) GN=Amet_3106 PE=4 SV=1
EEILIENYNMKLFLTNEGYIKKISLASLRS-------SGDHKLKDNDYIVQEIDGTNRGEVLLFSNKETVYKIKAYELEDSKASNLGQYLNNVLGLSS-E
IILHIVCTEDYQGHMLFFFEN--GKGAKIPITSYETKTNRKQLANAYSGDSPLVYISSIE---EMMATSNLNKTLIFNTEEMPINSRNSKGVQVFKCKKM
DEVSPDEMLNQ-GHMLFFFENGKGAKIPLESYETKTNRKQLANAYN----GESPLVYISNIQEDIELVATSNINKILIFNTAQINPKSRDSKGVQILKSK
EGYLQEIKAL--
>tr|A0A0G4B6L7|A0A0G4B6L7_9BACT DNA gyrase subunit A OS=Berkelbacteria bacterium GW2011_GWE1_39_12 GN=gyrA PE=3 SV=1
AEDLIPSEQVIVMLSKGNYIKRMPVSAYRSQVRGGKGVMGMETKEEDTIEHLVAANTHDDVLFFTDRGRLFQAKVYDIPSASRISKGQALVNILQMSPKV
TAVITLDAK-NEALKYFVMATEKGVIKKTEIELYKNVRKTGIVAIKLGAGDKLKWVKTTS--DKIFMASSRGQSILYNETDIRPMGRSAAGVRGILLKGE
DKAVGIDVILPKAFVLVVMENGLGKRTPLTHFKVQLRGGMGIRVAA----VTGKVVAMHVVYDKVDVILATKNGQMIRMPMDTIKILSRDTQGVTLVKLK
DNKVASVTVV--
>tr|K2A3Y2|K2A3Y2_9BACT DNA topoisomerase (ATP-hydrolyzing) (Fragment) OS=uncultured bacterium (gcode 4) GN=ACD_58C00295G0003 PE=3 SV=1
AEDLIPNEQVVITLTKTNYIKRVPIATYRSQNRGGVGVTGMATKEEDVVEHLLVAKTHDNIMFFTDKGRLFAAKVYDLPAASRQAKGQNIVNVLQISPKV
TTIITQSKDQKLKAKYFFMGTKFGVVKKTLIEAYENVRKTGLIAIKLNDGDELNWVTMTT--NSIIMVTRNGQSIYFGEKDVRPMGRSAAGVRGIKLRPG
DEVITMDVIPQNLDVFTVLGRGFGKRTMIKNFTKQRRGGIGIRASK----TSGKVVEALVVDNDGEVVIVSTHGQMIRMALKSVKRLGRDTQGVTLMRLK
PGKVASMTVF--
>tr|A0A0G0KEX0|A0A0G0KEX0_9BACT DNA gyrase subunit A OS=Berkelbacteria bacterium GW2011_GWB1_38_5 GN=gyrA PE=3 SV=1
AEDLIPSEQVIIIFTRGNYIKRMPVSSYRSQIRGGKGVIGMETKEEDMIEHLLVSNTHDDVYFFTDRGRIFHTKVYEIPTASRIAKGQAIVNILQISPKV
TAMITLSSSDIEKYKYILLATSKGLVKKTSMKLYSKVRKTGILAIKLRPEDRLRWVKVTT--ENVFQVSAKGQSIFYKETDIRPMGRTAAGVRGILLKGD
DYVVSTDVIPAKVDALIVLEKGFGKRTPLTMFNMQLRGGMGLRAAN----VTGPIVGMRLVSDNYDLILASRKGQVIRMALATVKKLQRDTQGVTLIRFN
QGKVTSVTII--
>tr|U5RX92|U5RX92_9CLOT DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium autoethanogenum DSM 10061 GN=CAETHG_3014 PE=4 SV=1
VDEIIIDEDIVITMSKEGYIKRTSLKSYN---RSSGKVEDIEYREGDFNEYFINSSTKDTLMFFTDSGDMYRIRGMDIPEFKWKEKGEKLDNLIKGIDKN
HITAVYSIKDFNLQKDFVFFTSIGGIKRTGIESFVT-NYTKLMALKLKNGEKLIGVELVDRSAFIKVETKSGLEFTVRSPEINLEDRNIVTTPLVTLQGE
DFAVKMDFSTE-GYVYFFTQYGMVKKTALMEFKQIAGCSTAYKFKD----KKDSLVNV-EYSEEIEIFLITERGMGIKFKANTVNTMGKLAAGVTAISLK
EDKVAYCFLI--
>tr|B9E358|B9E358_CLOK1 DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium kluyveri (strain NBRC 12016) GN=CKR_1882 PE=4 SV=1
VKEILVDEDIVITISKEAFIKRISLKSYN---RSSREVKDIEYREGDFNKYVINSSTKDTIMFFTDKGNMYKIKGMDIPEFKWREKGEKLENIIKGIDEE
NIVAVYSIDDFSSPQDFIFFTNMAGIKRTETNAFVT-KYTKLMALRLKKEEELIDVKLVNRNEFIKVETKIGLKFTVKVPELALEDRNIIANELCSLVKG
DKIVKMDLSEE-GYIYFFTKYGMIKRTELNEFKDINGWNTAHKFKN----NEDFLVNV-EYGEKNEILLITEKGMAIKFQGDSINSMGKSASGVTAINLK
GESVIYSMVM--
>tr|Q97IL2|Q97IL2_CLOAB DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787
VEEFTVVEDIVVTMSNDGYIKSVPKKTYL---RSNSDVSDIEYREGDFNRFLIETNTAHNLLMFTDEGNMYKLRGNSIPEYKWKEKGEKIDNLIKGIDKE
KILNIYSVESLTEQKDIIFITDRGSLKKTSLDKFDT-IYSKIMALKLKKDEKLIKAELVLRTRFIKVSTEKGLDFTVREPLIEEMDRNKMGHQCISVCPM
DRIVSSEFVENNKFIYFFSSKGFVKKTKLSEFVESKGIEVCYKLRN----KED-MLVNVDVSEEEEVVLITKKAMGIKFLSSSVSVMGKIASGVTGISLN
EEITEYGFVV--
>tr|M1N4I8|M1N4I8_9CLOT DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium saccharoperbutylacetonicum N1-4(HMT) GN=gyrA2 PE=4 SV=1
LEELIVIEDVVITVSKDGFVKRMPLKNYN---RSSSNPEDIEYREGDYLSFLVNSNTKDTLVVFTDKGFMYQTKGINISELKWKEKGERLDEIIKTLNEE
KIVSAISIDNFSPSNALRFITKKGGIKLSSLDKFQT-SYTKLQALKLREDDELIDVCLRELEEFLRVKSKLGLEFTLEVKALEDTSRNILPMQLFNFPKE
DEIIEVEDSEEDLAVYTFSKKGMIKKTLLKEFEGDFFKQVCYKFKY----EDDEVISTEVEQKFGHLIMITKKGMAIRFPVENVNTMGKIASGVTGISLR
DEEVIFGKYH--
>tr|U6EWY0|U6EWY0_CLOTA DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium tetani 12124569 GN=BN906_01914 PE=4 SV=1
IEDLIIDEETIITISKEGFSKRVSVKSYN---RSNSEIKDIEYREGDYNKFLLEGSTKDNVLIFTNKGNMYSTKVINIPEKRWKDRGIRLDEIIKTIDEE
EIIDIYVISNFTIQNDFIFITSRGGIKKTSLDKFET-NYSKLMALKLRENEEVIDVKLTDKNRFLKLSTKMGLDFTIEEPTIDEEDRNILSNIFCSLGYK
DKVIKSQFEDKDWEIYYLTKCGLVKKTLLKEFQGDYFITAGYKFRD----KEDEIIAVDFGKEEKDIIIISQKGMCIRFSKNSINPVGKIASGVMGINLK
KEKVLYGFIN--
>tr|N9WGU5|N9WGU5_9CLOT DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium colicanis 209318 GN=HMPREF1092_01541 PE=4 SV=1
VEELVVVEDVMITMSNDGFIKRIPYKNYI---RSNADANEIDYREGDFLRFLIESNTRDTLLIFTDKGNMYQIRGINIPEGKWKDKGERIENLIKGFNEE
KIINTISVTTLNQNNYIQFITNTGMIKNTSLDNFKT-NYTKLQAIKLKEDEEVVKATLFEGENFLRVKTALGLEFQLEIGEIKHQPRNILGTYLFNLSKE
DKVIEYEYIKEELGVYAVTKKGIIKKTSLKEFDGDYVTQGYYKLKS----SDDRVIMVLISPEIGNIVMVTKKGVTIKFPVDGVSAMGKFTSGVTGITLK
DGEVVYAKYM--
>tr|V9H7X9|V9H7X9_9CLOT DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium sp. 7_2_43FAA GN=CSBG_02037 PE=4 SV=1
VEELIVVEDVMITLSKDGFIKRIPLKTFN---RLNAKAEDIEYREGDELKFLFKSNTTESILLFTNKGNMYQTKGINIPEGKWKEKGEKVDNIIKTLNEE
NIIFATSVTSFIPSKYIQFITSRGGIKRSSLDKFQT-SYTKLQAIKLKELEEVIDVILLNQEEFISFETKEGLSFSLQIPKIEDLPRNILPTIMFNLSNK
DEIIKVEYSETNKFIYFFTRRGMIKKTALTEFDGNYSTQITYKFKY----DNDELISVELYDCQVEMLIITKKAMGIKFSSENVNTMGKVASGVTGISLK
ENEVIYGSLI--
>tr|A0A0G9L7S1|A0A0G9L7S1_CLOBE DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium beijerinckii GN=AAT22_14065 PE=4 SV=1
VEELIVVEDVMITLSKDGFIKRIPLKTFN---RVNANAEDIEYREGDELKFLFKSNTTENILLFTNKGNMYQTKGINIPECKWKEKGERVDDLIKTLNDE
TIVYTASVSSFMPNKYVQFITSRGGIKRSSLDKFQT-SYTKLQATKLKDFEEVIDISLLEEDEFINFETKKGLVFNLPIPSIEDSARNILPIMMFNLSNK
DEVTKVEYSDSNRFIYFFTKKGMVKKTSLVEFDGNYSSQLSYKFKY----DNDELISAEMYNNVAEIVIITKKGMGIKFSSENINTMGKVASGVTGISLK
ENEVIYGKII--
>tr|A0A0B5QGA7|A0A0B5QGA7_CLOBE DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium beijerinckii GN=LF65_04846 PE=4 SV=1
VEELIIVEEVMITISKDGFVKRIPLKNYN---RSSSNPEDIEYREGDSLKYLINSNTKDTLLVFTDKGFMYQTKGINIPEMKWKEKGDRLDDIIKSLNNE
KIIAAISIDNFNPSKAFRFITKHGGIKLSSLDKFQT-AYGKLQALKLRDGDELIDVSMRELEDFLKVKSKLGLEFTLEIKNLEETARNILPTQLFNFSEE
DEISQVEDTSEDLGVYTFTKKGMVKKTLLKEFEGDFLRQACYKFKF----EDDEVVSVEVNQKIGHLIMITKKGMAIRFPVENVNIMGKIASGVTGISLR
DEQVIFGKYH--
>tr|S6EPL6|S6EPL6_9CLOT DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium chauvoei JF4335 GN=CCH01_005110 PE=4 SV=1
LEELIVVEDVMVTISKDGFVKRIPLKTYN---RSNGKIEDIEYREGDELKFLVKSNTIENLLVFTNAGNMYQIKGINIPEGKWKEKGERLDSLIKTLNQE
TIVNVISVNSLHPNKYIQFITSKGCIKKSSLDKFST-SYTKLQALKMKDGEEVIRVDLFNEEEFLKVETKNGLNFSLEIPELEDQPRNILPLQIFNLSSK
DEILNVEYTNENKYVYFFTKKGMIKKTLLKEFEGNYSSQIAYKFKH----DKDEVISVDICDTNAEVIMVTKKAMAIKFSTENVNPMGKVASGVTGISLK
EDEVIFGRVF--
>tr|A0A0A6PYU7|A0A0A6PYU7_CLOBU DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium butyricum GN=OA81_08385 PE=4 SV=1
VEELIVVEEVMITVSNDGFIKRIPLKNYN---RSNSDPDDIEYREGDYLKYLISSNTKDNLLIFTNAGYMYQTKGINIPELRWKEKGERLDSVIKSLNDE
KIVGIISLDNFTPGKGFRFITSGGGIKISGLDKFQT-SYTKLQALKLRDTDELINVSLIDLEEFLKFTTRNELEFTLEIPEVEDATRNILPTQLFNLPED
DIVVDVNDSEEERCIYTFTKTGMVKKTLLKEYEGDFFKQPCHKFKY----EFDELVSVDIDKSLGYLIMVTKKGMAIRFPVENVNSMGKIASGVTGISLK
DDEVIYGKYY--
>tr|G7M9Z9|G7M9Z9_9CLOT DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium sp. DL-VIII GN=CDLVIII_5047 PE=4 SV=1
IEELIVVEDVVITISKEGFAKRIPVKNYN---RSNSEPEDIEYREGDSLKYLINSNTKDTLLIFTDKGFMYQTKGINIPELKWKEKGDRLDGIIKSLNNE
KIVGVISLDNFTPDKAFRFITKGGGIKLSSLDKFQT-SYAKLQALKLRDEDELIDVTIRDLDEFLKFKSKLGLEFTLEVKKLEDTSRNILPIQLFNFAQD
DEIIEVQDSEEELGVYTFTKKGMIKKTLLKEFEGEFFKQVCYKFKF----EDDEVISVEVNQKFGHLIMITKKGMAIRFPVENVSAMGKVASGVTGISLR
DEEVIFGKYH--
>tr|K6TIL8|K6TIL8_9CLOT DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium sp. Maddingley MBC34-26 GN=A370_05197 PE=4 SV=1
IEELIVVEDVMITISKDGFVKRIPLKNYN---RSSSNPEDIEYREGDSLKYLISSNTKDTLLIFTDKGFMYQTKGINIPELKWKEKGDRLDEIIKTLNNE
KIISAISVDNFNPSKAFRFITKHGGIKLSSVDKFQT-AYTKLQALKLRDEDELIDVSIRNLEEFLRIKSKLGLEFTLEVKNLEDTSRNILPTQLFNFSEE
DEIEYVEDSDEEYGVYTFTKKGMVKKTSLTEFDGDFFKQVFYKFKF----EDDEVVSVEVNKKFGHLIMITKKGMAIKFPVENVSAMGKIASGVTGISLR
EEEVIFGKYH--
>tr|U5MWJ7|U5MWJ7_CLOSA DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium saccharobutylicum DSM 13864 GN=gyrA2 PE=4 SV=1
VEELIVVEEIIVTISKEGFIKRLPLKNYN---RSNSNTDDIEYREGDSLQYIIKSNTKDNLLIFTDKGFMYQTKGINIPELKWKEKGERLDEIIKTLDKE
RVIGVISIDNLNPSKVFRFITKSGGIKKSSLDKFQT-SYTKLQALKLRDGDELIDISIKDIEDFLRVKSKLGLEFTLEVPKLENATRNILPVQLFNLSPN
DEVIEVQDTNEELGIYVFTKKGMVKKTLLKDFEGDCFRQGFYKFKF----EDDEIVSVDINRKLGYLVMITKKGMGIRFPVENVNAMGKMASGVTGISLR
DEEVIFGKYN--
>tr|Q8XIP7|Q8XIP7_CLOPE DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium perfringens (strain 13 / Type A) GN=parC PE=4 SV=1
LEELIVAEDVMVTLSNEGFIKKIPLKTYN---RSNVDENEIEYREGDYLKFLIKSNTKDTLAIFTDKGTVYQIKCNSVADKKWKDKGERLEDLIRGLSDE
KIIALESIENFLPNKCFKFITANGLIKKTTLDKFVT-AYSKLMAIKLKNDDLLASVSLIDSQDFVEIETTNGLNFVVSEPELEFTDRNILGVQLVPLKSG
NQIKSIRFVDNDLFVYFFSREGLVKKTSLREFLGEFNNQIAYKFKT----PKDELVNVDINF-NATVILVTKNGMGIKFSATAINPMGRVASGVTGISLK
DDKVIFGKVI--
>tr|W6SG85|W6SG85_9CLOT DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium bornimense GN=CM240_1562 PE=4 SV=1
IEDIIVSEDVVITLSNDGYIKRISQKSFN---RLSSGVEDIEYREGDFNRFLLQSNTKDTFMIFTDKGNMYQTKVNNIKEMRWKEKGERISEIIKSCTEE
SIVYATTIGQNNMNSDFIFITSKGFYKKTSIDKYVT-AYSKIAALKLKNDETLVMVDMVSKDEFLNVTLKSSLSFIVEEPEVQEGERMAATSKFLSLPNK
EEIIDANIVNE-GIVIFSTELGYIKKTRLQEFKKDEGVTIGYKLKT----ADDKLVHVDIIEDDVDYVMVTRKGMALRINTSTVSEMGKVASGVIAISLR
DEKVIYCNTV--
>tr|A0A0L8EYP5|A0A0L8EYP5_9CLOT DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium sp. DMHC 10 GN=AGR56_06360 PE=4 SV=1
VEEFAVIEDIVVTMSNEGYIKRVSQKAYS---RSNANTSDIEYREGDFNKYLFESNTVHNILFFTDNGNMYKIKGDSIPECKWKEKGEKLDNIIKGLDKE
KVINIFSIQDMQEDKNFIMFTDKGGIKKTGIDKFLT-NYSKIMALKLRKDEKLVKVIFDEDERYIEITTELGLSFKLEEPSIEEADRNVMSYTMFNLSSK
DRVVNINFIENGKYIYFFSKNGFVKKTALSEFDGDYLTTPCYKFRN----ESD-ELINAELGTESDIILVTEKSMCIRFQNNSVNPMGRIASGVTGISLN
EDFVKYGFIL--
>tr|A0A099S6C5|A0A099S6C5_9CLOT DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium sp. HMP27 GN=DP68_10225 PE=4 SV=1
IEEIIVEEDVVITLSNEGFIKRVPLKTYN---RSNTDVDEIEYREGDYNKFLIFVNTRDTLIVFTDKGNMYQIRTIALPEMKWKEKGEKIDDIIKGINEE
KIIDAYGIDNFAYQKDIMFITSTGGVKKTPLDKFST-NYSKLMALKLKNEDKLIKTYLIDRDRFIHVKTALGLNFTLEEPKLESVDRNILPQQMFNLSSQ
DEVVEIEVVESFDEVLFFTKKGLVKKTSLQEFNQDYSITTSYKFKA----EDDALLAIDFASEKSDIIIITKRAMCIRFDKESVSPMGRVASGVTGISLK
DGEVLFGAVI--
>tr|R4KBB2|R4KBB2_CLOPA DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium pasteurianum BC1 GN=Clopa_2994 PE=4 SV=1
LEELIVVEDIVVTISKEGYTKRISQKTYG---RSNTNVEDIEYREGDYNKFLLDSNTKHTIMFFTDKGNMYQIKGNAIPEYKWKEKGERLDTLIRALDKE
HIVNVFSIENILSQEDLIFITDRGFIKKISLDKFNS-NYSKIMALKIRNEESLIFIELVEKNRFLTIETKLNFQFTIEEPILEESERNNFGTKLFNLPNK
DSITRVEFNNELIDVYFFTKNGLIKKTALEEFKMENTSTIAYKFRG----KDT-LINVEFLNKDNDIIIITLKGMSIRFLSKNISYMGKIASGVTGISLD
EEEALYGFLC--
>tr|U2CK51|U2CK51_9FIRM DNA topoisomerase (ATP-hydrolyzing) OS=Clostridiales bacterium oral taxon 876 str. F0540 GN=HMPREF1982_03629 PE=4 SV=1
LDELIIVEDTVITLSNEGFIKRTPLKAFN---RINSSVEDIDYREGDFNKFFVESNTRHTVMFFTDKGNVYQIKGVSIPEYKWKDKGERLDDIVKGLDSE
KIISVFSFESLSESNNFVFITNKCNIKKTSIDKFIT-NYSKLMALKLKEDELLVSVSLSDNNSFIKVITEKGLTFAVEEPHLDAADRNIASTILAAIPPK
DKVVSTEFINEPISVYFFTKNGMIKKTLLDEFKGDYLTALAYKFKN----DKDKLIAVDFLSENKDIFVVTKRALGIRFRGSDVPSMGRAAAGVIAISLK
EDEVLFGSII--
>tr|V7I8V8|V7I8V8_9CLOT DNA topoisomerase (ATP-hydrolyzing) OS=Youngiibacter fragilis 232.1 GN=T472_0200090 PE=4 SV=1
ASDIMVEEDVMVTVSKDGFLKRLPLKNFQ---RVSSDVSAIEYREGDSCRLLVQSNTKEMLYVFGSSGMLYQIKTHLLPDLKWKEKGERLDEFVKGIDEE
EIVAAFTIRDPDEEAVVKFMTTRGGLKRTLLESFKT-NYSKISGVKLKDGEKVCAVVLERIPEFVRILTNRGLDFTVPEADVQIKDRMIVPDQFLTMPPQ
DEIARVHFENDDREVYMATEGGLVKRTPISDFVGDSMSGSVIRFKE----PDDRLAYAGAFPISASMLMVTEKGMAIRFETESISLLSKNASGVVGINLK
EERVFFASVV--
>tr|E3NTF6|E3NTF6_CAERE DNA topoisomerase 2 OS=Caenorhabditis remanei GN=CRE_15839 PE=3 SV=1
----------------VGMIKRTRIDNYRTQHRGGKGVKDAALRADDIVEHFFVTTTHHWLLFFTNTGRVYRAKTYEVPEGGRDAKGQHLANLLALAPDE
SVTQILDLREFEADRFLVLATRDGLVKKTALTEYDTNRTGGIIAIKLRDEDELVSALIAESDDDVLLISKHGMSVRFTASDLRPMGRSTSGVRGMNFRDG
DQLLQASRITEGGYVFVVTEGGYAKRTAVDEYRVQNRGGFGIKVAKLDE-ARGDLVGGFIVDEGDEVLAVLASGKVVRSNVAEVPAKGRNTMGVVFARFP
ERRIIGIARN--
>tr|A0A084F1F8|A0A084F1F8_9MOLU DNA topoisomerase (ATP-hydrolyzing) OS=Ureaplasma diversum NCTC 246 GN=parC PE=4 SV=1
-DDMIEKQDLMITISSQGYIKTVRKKSFESSKYNEAG-----IKTNDLLVYINHINSHHKINIVTSLGKLISIVAHKLPILKWKDIGEHLNNFVKCEGNE
SVIYAFISDNFDFSHQLLLTTKHNIIKKINLAECELNKPKSISVMKLADHDQLISAQLLKALNYVFISTSNGLGMIFSSHEVSLLSRTAKGIKACKLKLN
DYLSAYALEH-SNHNLALFLDGALKIVNLNDLKLSHRFLTPSNLFLSNKKIKP-VLASFLLTKGNGFYLLKNDGSVNVFALVDPKAASFDT---------
------------
>tr|A0A0K2EN89|A0A0K2EN89_MYCPM DNA topoisomerase 4 subunit A OS=Mycoplasma pneumoniae 85138 GN=parC PE=3 SV=1
-SDFIEHKEVGLLISHDGIYFKFEPEQLA-KHLVEFK-----SEQDQ-LIFGGVVQNSDYFFMVTSLGNIITVPIYKTLSNTKTKMNELLAKKPILMEDE
KLVLAG-IVPDKMQQLLVLTSQCGMVKRVELSKVINTKQKSSCCMALRERDKLVNAFVQTKEPKVCLVSSSNSFATFLAEEIPIISNKGIGVKGIKLKAE
EKVFAMPLQD-NDALVVINSDGGVYNFEVVELAVASRMSVGKKLIPKTKTPVSCAANSEIIGNGSDLFTLNELNRLPKSTVSQM----------------
------------
>tr|J3YH57|J3YH57_MYCGL DNA topoisomerase (ATP-hydrolyzing) OS=Mycoplasma gallisepticum WI01_2001.043-13-2P GN=parC PE=4 SV=1
-ASIIEKKELYLVSSVDGLIKTIAYDENKQLNPTSLK-----IKQDDYLSDLIKVSSLNKVAFITNYGNVVVINAHKIKQAKPREIGMDINELTTIKDNE
KIVKLVELSQ----DRIVLVSKYGMIKQISVNDLVNIKSKPTTCMSLKDDDELVCANLVSDNAELIIITKNAYALRFFINEVNLTGLKSMGVRAIKLKTN
DQVGFDQIKN-SIDQLVLVKNKQIKKLKASLIENQSRATQGKNLGLG-KDKKP-LVNGYLLNKEAALYGFNRDNELVNLELNQIMMGNLSS---------
------------
>tr|Q5FK07|Q5FK07_LACAC DNA topoisomerase 4 subunit A OS=Lactobacillus acidophilus (strain ATCC 700396 / NCK56 / N2 / NCFM) GN=parC PE=3 SV=1
-KALVADEKVRVLISRDGYLKRSSIRSYQSTDD--NG-----LPDGDKVIYENTLSTLTNLYLFTNRGNVIYRPVHELVETKWKETGQHLSQEIGLSSDE
KIIRVFAFDDLN-NSNFLLATNDGYIKQLELANLQPTRTRAMSAINLKSNSLLVGVDLIAPNDKITLFTNRAYAVRYNINEVPSSGAKAAGVKSVNLKDD
DYIVGYVLVDNLIKVGLITQRGAYKQFDLNLVNKVSRAKRGVLVLRELKTKPHRVA-IMPYA---ILDITTSSDRHIEIKTNEHPMGDRYS---------
------------
>tr|A0A0R2GPM8|A0A0R2GPM8_9LACO DNA topoisomerase OS=Lactobacillus acetotolerans DSM 20749 = JCM 3825 GN=FC77_GL000955 PE=4 SV=1
-KALVADEQVRVLISKDGYLKRSSIRSWQSSDE--NG-----LPDGDEVIYEKTLSTLTNLYLFTNKGSVIYRPVHELIETKWKETGQHLSQEIGLDTDE
QIIRVFSFDKLD-KVNFLMATNDGYIKQLQLANLQPTRTRAMTAIRMKKDSCLLRVDVVKPDKDIILFTHRAYAVRYDISEVPESGAKAAGVKSVNLKDD
DYVVGYVLTQPLLRVGLITQRGAFKQFKLKLVNKVSRAKRGVMVLRELKTKPHRVA-ITSYG---TLFLTTSSDRHMEIKTNEFPLGDRYS---------
------------
>tr|C2ENI8|C2ENI8_9LACO DNA topoisomerase 4 subunit A OS=Lactobacillus ultunensis DSM 16047 GN=parC PE=3 SV=1
-KALVADEQVRVLISRDGYLKRSSLRSYQSTDD--NG-----LPDGDKVIYENTLSTLTNLYLFTNRGNVIYRPVHELVETKWKETGQHLSQEIGLDSDE
QIIRVFAFNNLN-DENFLLATNDGYIKQLELANLQPTRTRAMTAIKLKSDSLLVGVDLVKPNKKITLFTHRAYAIRYDISEIPASGAKAIGVKSANLKDD
DYIVGYVLVDSLMHVGLITQRGAFKQFKLKLVNKVSRAKRGVLVLRELKTKPHRTA-LVPYA---ILHITTSSDRHIKIKTNEYPLGDRYS---------
------------
>tr|A0A0R1NZ93|A0A0R1NZ93_9LACO DNA topoisomerase OS=Lactobacillus kefiranofaciens subsp. kefirgranum DSM 10550 = JCM 8572 GN=FC94_GL001172 PE=4 SV=1
-TALVADEQVRVLISRDGYLKRSSLRSYQSTDD--NG-----LPDGDTVVYENTLSTLTNLYLFTNRGNVIYRPVHELVEAKWKETGQHLSQEIGLDTDE
QIIRAFTFSTLD-NVSFLLATNDGYIKQVELANLQPTRTRAMTAIRLKNDSRVVGVDLIKEAEKITLFTHRAYAVRYNISEVPSSGAKAIGVKSVNLKDD
DYIVGYVLVDKLIHVGLITQRGAFKQFKLELVNKVSRAKRGVLVLRELKTKPHRAG-FAFYA---ILQVTTSSDRHIEIKTNEFPLGDRYS---------
------------
>tr|A0A0R1HAB0|A0A0R1HAB0_LACAM DNA topoisomerase IV subunit A OS=Lactobacillus amylovorus DSM 20531 GN=FC63_GL000295 PE=4 SV=1
-KALVADEQVRVLISRDGYLKRSSIRSYQSTDD--NG-----LPDGDKVVYENTLSILSNLYLFTNRGNVIYRPVHELVEVKWKETGQHLSQEIGLDNDE
KIIRVFVLDKLS-NINFLLVTNDGYIKQLELANLQPTRTRAMTAIKLKNDSLLVGVDAVKPDKKITLFTHRAYAIRYDISEIPTSGSKAVGVKSANLKED
DYIVNYVLVDNLMHVGLITQRGAFKQFKLKLVNKVSRAKRGVLVLRELKTKPHRAA-LVPYA---VLHITTTSDRHVKIQTNEYPLGDRYS---------
------------
>tr|D5GXT5|D5GXT5_LACCS DNA topoisomerase 4 subunit A OS=Lactobacillus crispatus (strain ST1) GN=parC PE=3 SV=1
-KALVADEQVRVLISRDGYLKRSSLRSYQSTND--NG-----LPDGDKVVYENTLSTLTNLYLFTNKGNVIYRPVHELIETKWKETGQHLSQEIGLDSDE
QIIRVFVFDKLN-DCNFILATNDGYIKQLELANLQPTRTRAMTAIKLKGDSYVVGVDLIKSDHKITLFTHRAYAIRYDVSEIPTSGAKAVGVKSANLKDD
DYIVNYVLVDSLMHVGLITQRGAFKQFKLKLVNKVSRAKRGVLVLRELKNKPHRVA-LMPYA---LLHVTTSSDRHVNIKTTDYPLGDRYS---------
------------
>tr|D4YV05|D4YV05_9LACO DNA topoisomerase 4 subunit A OS=Lactobacillus amylolyticus DSM 11664 GN=parC PE=3 SV=1
-KALVADEQVRVLVSRDGYLKRSSLRSYQSSDE--NG-----LPENDKVVYEKTLSTLDNLYLFTNRGNLIYRPVHELTETKWKETGQHLSQEVGLATDE
QIIRVFDFDKLD-NVDFLMATNDGYIKQVKLSDLQPTRTRAITAMKMKSDSKMIRIDLIKTN-GITLFTHRAYAVKYDVSEISEFGGKALGVKSVNLKDD
DYVVGYVLVQPLIKVGLITQRGAFKQFKLSLVNKVSRAKRGVMVLRELKTKPHRAA-IAAYG---VLKMTTSSDRHMDINTNKFPLGDRYS---------
------------
>tr|E6U299|E6U299_BACCJ DNA topoisomerase 4 subunit A OS=Bacillus cellulosilyticus (strain ATCC 21833 / DSM 2522 / FERM P-1141 / JCM 9156 / N-4) GN=par
-EVVIPSEDVRVTVTKEGYVKRSSLRSYAASNG--PG-----MKETDRLLYSLEINTTDTLLLFTRKGSFLFLPVHQLPEIRWKDSGQHVANLVAMDNDD
DILTAIPVKEFN-SEYVLFATKLGMVKKTVLSEYKAQRNKALMAVKLKKD-EVISVTLSDG-THIFFATHTGYGLWFTEEEVSATGQRTAGVKAINLKKD
DFVVSCMSFKEPPDLFLVTQRAAYKKMKLNVFEKTSRAKRGLVMLKELKRYPHRAS-LLPIT--GSIFVQTKNGNTDTIEVASIRSNDRYT---------
------------
>tr|D6XUE0|D6XUE0_BACIE DNA topoisomerase 4 subunit A OS=Bacillus selenitireducens (strain ATCC 700615 / DSM 15326 / MLS10) GN=parC PE=3 SV=1
-EVVVPSEEVRVSVTKDGYVKRSSIRSYTASNG--PS-----MKETDRLIHDLEVNTTDTLLFFTKKGSYLFVPVHQLPETKWKDGGQHIANIVTMDQDD
PIIHAIPVQEFR-DRWLLFATKSGMVKRSVLKDYHAQRHKALTALKLKTD-ELINVYLTNG-EELFLATKKGYGLWFSEEEVSVTGQRTAGVKGINLKEG
DQLAALSVFNNKPDFVLVTQRAAVKRMALKSFEKTTRAKRGVIMLKELKKAPHEAA-CMAVH--ETLVLESETRTRHAVIPKQLRLSDRYT---------
------------
>tr|X0QKM8|X0QKM8_9LACO DNA topoisomerase 4 subunit A OS=Lactobacillus composti DSM 18527 = JCM 14202 GN=parC PE=3 SV=1
-SVLVSDEEVRVAVTRDGYFKRSSLRSYQASVSKDNG-----IRENDQFVLNTVAGTLQHLFIFTSKGNMIYRPIHEIDDVRWKEVGEHISQSVGLDGSE
SIVAAYVVPKLD-ALNFVLATKYGQIKQVELANLQPNRTKPQLAIKLKQEDEVLQVYQIQTAQFVVSATHLGYGVRYPLAEVPAVGAKAAGVKAMDLKPD
DYIVSFILTDSKDSLGLLTQRGAFKQMHLSELPISSRARRGVLLLRELKRNPHRFA-LIKEP--KAVDILTTTGVRIQIDPKTHNFGDRYS---------
------------
>tr|A0A0R1N2A3|A0A0R1N2A3_9LACO DNA topoisomerase (ATP-hydrolyzing) OS=Lactobacillus perolens DSM 12744 GN=FD09_GL001269 PE=4 SV=1
-SVLVSNEEVMMGVSRDGYLKRASLRSFNASDE--NG-----LKENDQFVFQDIVHTLDHVYMFTSLGNMIYRQVYEIQDGKWKDTGEHISQTTGLAADE
KILFVTVLKSLD-PGRFVLGTRAGQIKQLTLTEFQPSRTRAQVATKLKSNDAVTDVYFVTDDDWVTSFSAHGYATRYPLTEVSAMGGRAVGVRSQNLKKD
DTVVGFMLTKDKTQVGIMTSRGAFKRMAVDQIPTAHRGGVGVLVLRVLKANPHRVL-VAPVT---TWNVLTDHDKHITVTPMNHPLADRYS---------
------------
>tr|A0A0R1XIW7|A0A0R1XIW7_9LACO DNA topoisomerase IV subunit A OS=Lactobacillus harbinensis DSM 16991 GN=FC91_GL001836 PE=4 SV=1
-SVLVSDEEVMMGVSRDGYLKRASIRSFNMSDD--NG-----LKENDQFVFQGTVHTLDHVYMFTSAGNMIYRQVFEIQDGKWKDTGEHVSQTTGLAADE
KIIYVKILKDLS-TGRFVLGTADGQIKQLALSDFQPSRTRAQIAMKLKGGDLVTDVFYVANDDWVTSFSRHGYATRYPLNEVSAMGGRAAGVRSQNLKGD
DTVVNFLLIRVNPQVGIVTSRGAFKRMAVEQIPDAHRGGVGVLVLRVLKSNPHQVL-VAPVA---DWDVLTDAGRHIDIKPMDHPLSDRYS---------
------------
>tr|U4TQU3|U4TQU3_9LACO DNA topoisomerase 4 subunit A OS=Lactobacillus shenzhenensis LY-73 GN=parC PE=3 SV=1
-SVLVTDEEVMMGVSRDGYLKRASLRSFNASDE--NG-----LKENDQFVFQGSVHTLDHVYMFTSAGNMIYRQVFEIQDGKWKDTGEHVSQTTGLASDE
KIIYVRVMTALD-PGRFVLGTASGQLKQLALADFQPSRTRAQVAMKLKGDDRVTDVFFVTSDDWVVSFSRHGYATRYPLNEVSTMGGRASGVRSQNLKKD
DVVVDFLLTKPSLQVGVITSRGAFKRMAADQIPDAHRGGVGVLVLRVLKTQPHQVL-VAPVT---DWDVLTNAGKHIVVAPMDHPLADRYS---------
------------
>tr|A0A0R1JMF1|A0A0R1JMF1_LACSK ParC protein OS=Lactobacillus sakei subsp. sakei DSM 20017 = JCM 1157 GN=FD49_GL000422 PE=4 SV=1
-SVTVIDETVMVAVSHDGYLKRSSLRSYQASEG--GG-----LKEGDFAILQKPMQTLDQLMLFTNSGHLIQRPVHEIADLKWKEMGEHISQSIGLAADE
AIIAAFSFTPNE-NGYFVIGTTDGYIKQTAFQDLLPSRTKAQDFIKLH-GANVTNVYWVSETQQVFSASYNGYGLSFALNEVSVSGAKAGGVKLMDLKDG
DHVANFTLFDPHAAVAIITQRGAFKRMFLSEIGLTSRARRGVLILRELKRDPHRAA-MIRVA---TLLV-KTEQALLTIEPQAHATGDRYS---------
------------
>tr|A0A0G7ZLD9|A0A0G7ZLD9_9MOLU DNA topoisomerase (ATP-hydrolyzing) OS=Candidatus Hepatoplasma crinochetorum GN=HEPPS_01920 PE=4 SV=1
-KELLIEESFYLCLTRNGYIKLVDLKAKENFEDDNFA-----FLNGDIPLKAIKVSNLNNLFIFTSKGKFYKIPIYKIGKFKYKDIGDHLSKYISINGRE
TIISLTVNKEISNNLKIIIATKNGMIKQTKISNLNLNISGGQKFIKLEESDYVASINFIESKNYVITFTEKGYYLKYNSNNVPTTSLNSSGVKNIKLLPS
DYVNVFLILEKKSKFLIFTKEGKGKRIRVKDLKEGKRNLRGNLILKEIKSYQD-----KLIGLDQKINILYKDNEMEYFDPNEIILSDFMS---------
------------
>tr|W8GT03|W8GT03_9MOLU DNA topoisomerase (ATP-hydrolyzing) OS=Candidatus Hepatoplasma crinochetorum Av GN=parC PE=4 SV=1
-EELIIEEDYYLCLTRKGYIKIVNSKTKDNLENDLFA-----FLDGDIPLKANKVSNLSNLFLFTSNGKFYKVPIYKINQYRYKEIGDHLSKYISLSGKE
MIISFIISKDITKDLNFIIATKKGMIKQTKIRNLNFDVSGGQKFIKLEKNDDVCSIQFIEKNKYVISFTEKGYYLHYDLNSLNVIGLNAIGVKNINLLPS
DFVNSFIIDQKKTKFAIFTKMGKGKRIRGKDLKITKRNLRGNLILKQVKAYQD-----KLVGFEKNIYIMYSDKKIQQFQFNEIILSDFMS---------
------------
>tr|R7DMQ9|R7DMQ9_9FIRM DNA topoisomerase (ATP-hydrolyzing) OS=Coprobacillus sp. CAG:826 GN=BN794_00330 PE=4 SV=1
-RDLIAKEEVMVAVTRDGYVKRATLKSYKASE---FG-----MKAGDVLVAASKAMTTDYLLLFTDGGNYAFVPVHEITESRWKEEGKHINLNVNVSGEE
KIIKALIVSSFKEGVYVALLTKNGQIKRTALKEFFLQRYKPVMCMRLLKDDEVVDVAITTGNNDLLVLFEEGNATLFNENELAVLGIKAAGVKAISSKNA
HAKFLFSYPQGWNKLLILSHEGALRTFDFTSLQTTARLGRVQAIFKCFVSNPHTLCYAKRMVAFN-LTGVLSNKSMMDIVVDDFHPVPSDK---------
------------
>tr|R5V532|R5V532_9FIRM DNA topoisomerase (ATP-hydrolyzing) OS=Firmicutes bacterium CAG:631 GN=BN742_00490 PE=4 SV=1
-VSTVIKEDVMVAISRDGYAKRSQLKSYNSSN---FG-----YKQTDAIVAISQASTLDTLLVFTSGGNFMYLPVYELVENKWKDEGVHINKIASFPSNE
KIINAFVVKEFRDDLYITLASSKGSIKRTALSEFVLQRYKAVSCFRLQEGENLVAAFLTNGGCDIVVLYKNGALVRYDENQVGIVGLKAGGVRSGSRALD
CD-GGIALDEE-MNMMIVTDKGGLKPVYPRYINQTNRTTVGTLSFKSFRSDHHDAVGIITY-----ILQVVTNFKSMDVLVDDVPYQPIDK---------
------------
>tr|F1Z0Z8|F1Z0Z8_9STRE DNA topoisomerase 4 subunit A OS=Streptococcus parauberis NCFD 2020 GN=parC PE=3 SV=1
-ASLIVEEETFVSVTRSGYLKRTSPRSFNASSI--IG-----KRDDDQLVFVEAAKTTQHLLIFTNLGNVIYRPIHELTDIRWKDTGEHLSQTINYGTDE
EVLHVEIVDQFT-G-TYYSVTQLGQIKRFERKDLAPWRTKSTKYAKIKNQDRIISISPIFF--EITLVSHNGYALRFSSQEVPVQGLKSAGVKAMNLKND
DYIASAFIVQS-DSFFVLTQRGSLKRVAITDIPQTSRANRGLLVLRELKSKPHCFL-ADSVKKSSVLEVTSKTGQVYEVQLNNLNLSDRTS---------
------------
>tr|A0A0R2D4F1|A0A0R2D4F1_9LACO DNA topoisomerase IV subunit A OS=Lactobacillus rennini DSM 20253 GN=FC24_GL000783 PE=4 SV=1
-KVIVADETVMVAVSHDGYLKRSSLRSYHSSAT--NG-----LKNEDFLTFQRPLSTLDHLLMFTNKGHVIYRPVYELSDGRWKDTGEHISQSIGLAPDE
YIIHTFAFNDLK-TGHFVLGTSDGFIKQTPFTDYLPGRTRAAQAIRLKHTAQVTNVYYVPAAQLVFLASYTGYGLRYALAEVPVNGAKAAGAKAMALKSE
DHVADFVLVDTNIPVTLITQRGALKRMKVQEVTKTSRARRGMLILRELKRQPHRQL-MAPPL--QKLLLQTNTKQTILIDPAQHPISDRYS---------
------------
>tr|A0A0R2LB38|A0A0R2LB38_9LACO DNA topoisomerase IV subunit A OS=Lactobacillus siliginis GN=IV55_GL000873 PE=4 SV=1
-TVTVADEDVIVMVSHDGYIKRSSPRSYQASAE--NG-----LKDEDYPILLTQASTLDHIFMFTSKGNMIYRPVHELADARWKDTGEHISQSIGLADDE
ELIAAFSFNSLE-QGNFVIATQDGLIKQTAFGDLLPGRTHASMYVKFKATDQVVNISYVDQ-PLVMLMSQHGQGLRYDLAEVPTNGARTSGAKAMDLRNG
DLVVNMQLVSE-DDAIIVTQRGALKKMAVKEVPVTSRARKGVLCLRELKANPHEAA-FLALP--TPVEIITTRGIRHDVLPADHELNARYS---------
------------
>tr|A0A0R1RJF9|A0A0R1RJF9_9LACO DNA topoisomerase IV subunit A OS=Lactobacillus rossiae DSM 15814 GN=FD35_GL000224 PE=4 SV=1
-TVMVADETVVLMVSHDGYIKRSSPRSYQASSE--NG-----LKEEDYPILLKPVSTLDHLFMFTSKGNLIYRPIHEVTDARWKDTGEHISQSIGLADDE
ELIAAFTFSSLE-PGNFVIATAHGLIKQTAFMDLLPGRTRASVFEKFKQDDQVVDITYVDS-PLVMLMSRNGLGLRYDLAEVPTNGARTSGAKSMDLRGD
DIVVNMQLVKD-DDAIIVTQRGALKKMAISEVPVTSRARKGVLCLRELKANPHEVA-FIAVA--APVEVVTSRGIRHDILPAEHERNARYS---------
------------
>tr|A0A0F4KTK9|A0A0F4KTK9_9LACO DNA topoisomerase 4 subunit A OS=Lactobacillus mellis GN=parC PE=3 SV=1
-RVMVTPEQVRVLVSRQGYLKRSSLRSYQASTA--NG-----LRPEDYPILDCEASTLDHLYIFTNQGHLIYRPVHELSDLRWKETGQHLSQSIGLNPDE
EILTAFIFPDLK-TGRFVLATSDGYIKQVDFQDLLPGRTRALKTMKLHQTSKIVQVFYLPSQDLVLGFTEHSYALLFNLNEVPVVGAQAAGVKFLALKEA
DQIVDFAIVDPPQFIVLLTKKGNFKKMSLSEITPGTRARRGTLVMRELKKQPHQQF-ARVLT---VLTVITDKLATITIDPQNFNFKPRSA---------
------------
>tr|A0A0R1F9Y6|A0A0R1F9Y6_9LACO DNA topoisomerase IV subunit A OS=Lactobacillus coryniformis subsp. coryniformis KCTC 3167 = DSM 20001 GN=FD22_GL000673 PE=4 SV
-KVVVADEAVIVAVSHDGYLKRSSLRSYNSSTD--NG-----LKDEDFLIFQQQLSTLNHLFMFTNKGHVIYRPVYEISDARWKDTGEHISQTIGLAADE
AIIRTFAFSELK-GGQFVLTTTDGYIKQTEFSEFLPGRARAAQAMRLKDSAFVTDVIYIQPDQYVFLASYTGYGLRYPLSEVPVIGAKAAGTKSMALKDG
DHVVNAVLVPRATPVTIITQRGALKRMDVQEITETSRARRGMLILRELKRNPHRQI-MTGPL--AKLLVQTDTRQTFFLTPDEHPISDRYS---------
------------
>tr|A0A0R1GK29|A0A0R1GK29_9LACO DNA topoisomerase IV subunit A OS=Lactobacillus bifermentans DSM 20003 GN=FC07_GL000847 PE=4 SV=1
-KVLVAEEDVMVAVSHAGYLKRSSLRSYHAT-E--DG-----LKDEDFPIFQQQLSTLDHLLMFTSHGHVIYRPIYEITDSRWKDPGEHISQTIGLAENE
VILKAFAFPDLK-TGHFVFVTSDGLIKQSAFDQFLPGRTRVAQAIKLKDAAQVVDVLYVPVDQRVFLATHRGYGLRYALSEVPESGSKAAGAKAINLTAE
DQVVGFVLVDPTEPVAVLTQRGALKCMAAQEVTKTTRGRKGMLILRELKRQPHRQV-LAAV---PTLLVQTDQNQLITLDLTAHPLADRYS---------
------------
>tr|B3F5G4|B3F5G4_STREQ DNA topoisomerase (ATP-hydrolyzing) (Fragment) OS=Streptococcus dysgalactiae subsp. equisimilis GN=parC PE=3 SV=1
-ASLIAEEETFVSVTRGGYLKRTSPRSFNASSL--VG-----KRDDDELIFVKQAKTTEHLLLFTTLGNVIYRPIHELTDLRWKDIGEHLSQTINFATEE
EILYADIVTSFD-G-LYLAVTQNGFTKRFERQELTPWRTKSTKYVKLKDKDRVVTLTPIVM--ELLLVTYHGYALRFSSQDVPIQGLKSSGVKGINLKNE
DKLVSTFSVTS-NSFFVLTQRGSLKRMAVDDIPQTSRANRGLLVLRELKAKPHRFL-AGGVQSAQMLEVISKTGQTYEIALETLSLSERTS---------
------------
>tr|G5K2Q0|G5K2Q0_9STRE DNA topoisomerase 4 subunit A OS=Streptococcus ictaluri 707-05 GN=parC PE=3 SV=1
-ASLILEEETVVSVTKGGYIKRTSPRSFNASSI--IG-----KKDDDDLLMVQQAKTTEHLLLFTNMGNVIYRPVHELVDLRWKEIGEHLSQTINFATDE
TILHAEILQGFD-G-QYVAVTANGFVKRLERKYLSPWRTKSTKYIKLKDQDEVIKISSIVM--ELLLITQHGYALRFSSQDVPQQGLKSAGVKGINLKEH
DRLSAALIVSG-DSFFVLTQRGALKRVALSDIPQTSRANRGLLVLRELKAKPHRFY-AGMVQNSQKLLVLSKTGQEYQINLESLPLSERTS---------
------------
>tr|A0A0P6S6X5|A0A0P6S6X5_9STRE DNA topoisomerase IV OS=Streptococcus phocae GN=AKK44_01870 PE=4 SV=1
-ASLILAEETFVSVTKGGYIKRTTPRSFNASSL--VG-----KRDDDDLIFVQQAKTTDHLLLFTNLGNAIYRPVHELTDLRWKDIGEHLSQTINFSTEE
TILYAEIVQSFD-G-LYYAVTQKGVIKRFERTALQPWRTKATKFAKLKGSDHIISVGPIVM--EFLLVTQQGYALRFASQEVPIQGLKTAGVKAINLKDD
DVLASAVPVTA-SSFFVLTQRGALKRVAVSEIPQTSRANRGLLVLRELKAKPHRFL-ADMVTTVQSLLVISQTGQDYTISLETLPLSERTS---------
------------
>tr|A0A0R2JCL3|A0A0R2JCL3_9LACT Uncharacterized protein OS=Weissella kandleri GN=IV73_GL000766 PE=4 SV=1
-SVTVADEDVMVLVSQAGYVKRASLRSYKASGD--NG-----LREDDMSVFSHKLNTMQHLFMFTNYGNVIYRPVHELPEVKWKDAGEHLSQTVDLRPEE
QIIQVKVVDDLEKTGHWVIGTSEGAIKQVAFATLQPRSNRAMPLVKFKNGV-LVLLQYVL-NQAVLLISNQAQGLRFNLTDVPVQGNRTAGVKAMNLQND
DYLIGGGVITQEMLIHVVSNRGAYKRMAVDDIPSTSRAKKGVAVMRELKKDAHRVA-AQVLP--VQLVLQTDTNQAILIQPTDHPISQRYS---------
------------
>tr|A0A075TYZ1|A0A075TYZ1_9LACT DNA topoisomerase 4 subunit A OS=Weissella ceti GN=parC_1 PE=3 SV=1
-NVTVVTEDVMLLVSKGGYVKRSSIRSYNASGD--NG-----LREDDDVVFMQEVNTLQHVFMITDRGNVIYRPVHEIAEMRWKEPGEHLSQTIGLNPDE
LIIAVKVVADVVNPGEWLVATQSGLIKRTQFADLAPRSNKATPVIKLKTTDSVVGLQWFNPEASIVLTSYQGNGLRYDLSEVPTTGARTAGVKAMSLEAE
DDMITGMGIVSTQALALITNRGAFKWMAIDELPTTSRARKGVAIMRELKKEPHRVA-SAVLD--NPLTIVTGMDKVFTINPLDYPLNQRYS---------
------------
>tr|F8HY04|F8HY04_WEIKK DNA topoisomerase 4 subunit A OS=Weissella koreensis (strain KACC 15510) GN=parC PE=3 SV=1
-TVTIADEDVVMLISKSGYVKRSSLRSFSASGN--NG-----LRDDDEPVYLEKVNTLQHVFIFTNYGNVIYRPINEIPEFKWKDAGEHLSQTVDLRNDE
TISQVVVLDDIDKNGQWLVASNEGYIKRVDFATLTPRSNRLIPLIKFKTTGKVALLQFIEPAPAVILITQKAQGLRYSLDEVPVQGNRTAGVKAINLNSD
DQLIGGGFVQTNMAIHLISNRGAYKLMKTDEIPVTSRAKKGVAVMRELKKDSHQVT-MILTP--PQLSITTDQNQIVLINPSEHSFGQRQS---------
------------
>tr|U4KRN7|U4KRN7_9MOLU DNA topoisomerase 4 subunit A OS=Acholeplasma brassicae GN=parC PE=3 SV=1
-ADLIADEQVRVGITKDGYIKRANLRSYTASK---QG-----LKENDGMLFNQEVSTKDTLLMFTTKGNYIFMPVYELEESKWKDLGAYINNIISIEKDE
YIIKVFSISDFETNQYFLLTTEHGLIKQVLLKDFLVTRYKTIRAMKVASSDELTSVELGPK-SSVIVFTKRAQVLRFPSAEVPIYGTQSGGIKSLKIAAN
DKVKAIYAATS-DDFLVLTHLGNIRRERVVNMPLNKRLRTPITLFSERKKNPHFIRDVARLTKEDSMILVSCKKGSLEFPISELKPSVAEY---------
------------
>tr|A0A088T4J9|A0A088T4J9_9MOLU DNA topoisomerase 4 subunit A OS=Mollicutes bacterium HR1 GN=parC PE=3 SV=1
-EELITEEQVIIGITREGYVKSTSIRSFKATE---QS-----LRDNDSMLFSGEVSTLDVMLLFTNLGNYIYLPVYKMPVFKWKDLGTHINNLVQLSENE
SIVKILKIRNFKEQRNLLFVTKNNLVKQTELKEFEVSRYKPVRAISLSKNDEVVSVDITESDAELVIFSAKGQALRFNLCEIPVTSTTAKGVKGMNLGQK
QELSGIVLKDY-HDLLLLTNRGTIKRINVNEIPKKKRTNKGVQIYKEVRSNPYLVQDLCLLNKNRAKITVNTTTTSVDISSFDIKHDKTEN---------
------------
>tr|A0A094IFD8|A0A094IFD8_9MOLU DNA topoisomerase 4 subunit A OS=Mollicutes bacterium HR2 GN=parC PE=3 SV=1
-EELVIEEQVFLGITREGYVKKSTPRSYKATD---KG-----LKDNDSMLFVDEVSTLDTILIFTNKGNYIYLPVFEVPDYKWKELGTHINNIVQLEEDE
IFIKIVHVTDFNANIHLFFTTKSNLIKLTKLEEFNVSRYKTIKAINLNKNDEVVGIDLTDSDAEVLIVSSKGLGLRMNMSEVPITSTTAKGVKGMNLPPK
QKLSGIVLKEY-NDLLILTHRGTIKRVSLSDIPKKKRTNKGVQIYKIVKSNPFLITDLCLLNKNRAIISINTTKTRVLISAFDVKTDKTGN---------
------------
>tr|A0A061AB60|A0A061AB60_9MOLU DNA topoisomerase 4 subunit A OS=Acholeplasma oculi GN=parC PE=3 SV=1
-KDLITDEQTIIGITKDGYVKRSSLRSFNASK---EG-----LKENDALLFEKEVNTLQTLIIFTNLGNYLFLPVYKIEDQKWKDLGVYINNIIPIEKNE
KVIKVYAIETFKNDTKLLLTSKQGLMKQVNLTDLEVTRFKPIRAMKLSKDDELIFVDMNEL-ENIISISKNGYILRFETSELPLYGLQAGGVKSMALGEH
DEVVAFYAKPT-DDFYFLTSRGHVIKDTVSELPKYARNRRGIILIERIKTSPHFIVSAARASKENVKVRLLSSKELLETDLQDLKYSNNKF---------
------------
>tr|A9NF72|A9NF72_ACHLI DNA topoisomerase 4 subunit A OS=Acholeplasma laidlawii (strain PG-8A) GN=parC PE=3 SV=1
-KDLISDEQTYVAITKDGYVKRASLRSVVASK---EG-----LKENDAMLYEEELNTLDTLLLFTNLGQYIYLPVYKIEEQKWRDLGVYINNIVPTSKGE
TIIRVLKVSDFSIDQKILLTTKQGQMKQVNLADFEVSRYRPLRAMKLSKDDELVSVDYNQL-DNIVAISKHGYVLRFDTEELPVYGLTAGGVKSMALAEG
DEVVAFYAKES-DDFYFLTSRGHIIKDTVLELPKYARNRRGIILVDRIKTSPHFIISASRVSKEDVKVRILSTKEALITTVSDLKYVANKY---------
------------
>tr|U4KRZ8|U4KRZ8_9MOLU DNA topoisomerase 4 subunit A OS=Acholeplasma palmae GN=parC PE=3 SV=1
-TQLITDEKVVVGITKDGYVKRSSLRSYNASN---LG-----LKEHDAILYEEEVQTLDTLLLFTNLGNYIFLPVHKIDDQKWGDLGTYVNNIVTISKDE
KIIKVYCISNFKVNLNLLLATKQGMMKQVKLEDLEISRYKPVRVMKLSKDDEVVSVDMNQK-NNIVVLSQNGYALRFKTEELPLYGLTASGVKGIALSEN
DSAVAFYAKDS-DEFYFLTNRGHIIKDNVYELPVYSRYRKGIMILERQKTNPHLVMSASRLSKDNVAIRILSDKTGLLMPLSEVKYTPNKF---------
------------
>tr|R5ZS38|R5ZS38_9CLOT DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium sp. CAG:568 GN=BN713_00614 PE=4 SV=1
-KSLIAKEDVMVVLTKTGYFKKTNMRSYQSTINGDMT-----IKVGDQIVLNRQATTHDDLLGFTSKGNYILVPVWQIPDAKWHDEGKHLNNVLTMDSNE
KIVSAYIIREYKKGLYVTLLSKLSKIKRVSLSDITSGKLKPLRIMGITKEDEVVSAQITSGDSDLLVIAQDGNCNRFNENEVPVVSFQAAGVKAMNQPIK
PVDCLLSLDKG-SKAVFVFEQRKSVVINTSGIASTQRLGAKTQTVRIPKSSYTKIVGVDMLKKIN-NILLSMSDGTVSLEVSNITCSDLGV---------
------------
>tr|R7FMH8|R7FMH8_9CLOT DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium sp. CAG:288 GN=BN588_00905 PE=4 SV=1
-KELIAKEDCYVVLTKDGYVKRTNLRSYQASVNGNLK-----IKVGDRIVLSRLATTHDSVVAFTSKGGYFVIPVHMISEGKWKEEGKHLNTLITLPADE
KVIQAFIVSTFEPKVYFALLTKEGKIKRTLAKEFEQSKLRPLRAIGLTGADELVSVALTSGNSDIVIVNTNGQASRFNENEVPVVGIKAGGVKAMNQGKE
IYDCMFALNSD-VKLLLLADKRCARIIQSTSIETSKRLGSKVSLVKIFKNNPMDIVSVSKVYTNN-FVAIATDSGSEIVNINDLETTLLGS---------
------------
>tr|R6XWC0|R6XWC0_9FIRM DNA topoisomerase (ATP-hydrolyzing) OS=Firmicutes bacterium CAG:345 GN=BN617_01024 PE=4 SV=1
-RSLIAKEDVMVVLTRDGYIKKTALRSYEASIQSSFK-----LKVSDKTVFCQKTTTHANIVFFTNKGLYYSIPCHLISDAKWKEEGKHINNLVNLEPKE
KIVSAFAVEDYKKGLYFALTSKLGKIKRTEIIDFECQKIKGLRAMPLVDGDELVSAILTHGNSDIMVMTDQGQVSRYNENEVPIVSTKASGVKAINFGSN
EKSATLSYKND-SLILILNDKNGARLLNSSVFPCFARLGQKTAACRIFKSSPMTIISMDKIYVPC-IVPLATENGLLPVDLNSLEVSQLGA---------
------------
>tr|D5E651|D5E651_MYCCM DNA topoisomerase (ATP-hydrolyzing) OS=Mycoplasma crocodyli (strain ATCC 51981 / MP145) GN=MCRO_0636 PE=4 SV=1
-KDLVKEEIVNIAFSKLGYIKRLSQKVVDSNDFSTFA-----LKEDDYLLYIDKANTVHNFLVFTNWGNYAIIPVYKIQETKWKELGTHLSAFVDLAPGE
NIINVIEVEDWNSPDFIVMATKLGFFKRTKIKDFEVSRTKTYTAINIDNKDEVINVAVSDGTKDILIITAMGFATKYNEAEISLYGPKAKGTKGVYLVNK
DFVACFTPTHFNDIVIMISDDGYIKKMKSREIYYVPKTAKGKEIFKNRKLNPY--F-ISDMHNDEKILIKLEDNKIAVRSTKDYSITNSDD---------
------------
>tr|A0A0F6SYG1|A0A0F6SYG1_9MOLU DNA topoisomerase (ATP-hydrolyzing) OS=Mycoplasma canis GN=AAW50_03475 PE=4 SV=1
-TDLIKDESTYIAISKLGYVKRFSERIAEANSLSTYT-----LKEDDSLIYFNKTNTMKTLLVFTSLGNYIQIPIYKINETKWKDLGSKLSDIAEFKINE
KVVSIIEVTNWSENVFVILGTKQGLFKKVKLSDFKIQRLKSYTAIGIANDDELINATLSNGLLNIVIITESGLASMYTETDVAIYSPKAKGNKGVYLSLN
DKVAGFTVVNSADIVNIVSSSGKLKQIKSSEILPIPKNIKGKKIFDSKLNGTI--K---DVHD-DKIVALNGNNQCLIEKISDYTNNKISS---------
------------
>tr|F9QD07|F9QD07_9MOLU DNA topoisomerase (ATP-hydrolyzing) OS=Mycoplasma anatis 1340 GN=GIG_01563 PE=4 SV=1
-KDLIKEEIINVAISKFGYIKRLSQKVIESNDFSTYV-----LKDEDYLTFYNQVNTMDTLLIFTNFGNYAIIPIYKIEECKWKENGVHLSDFVDLQSGE
VVVSVIEVSDWNSNLFVTIATRNGIVKRTPIKEFEVTRTKTYTAINISADDRVVNACLSNGSKDVILVSSFGLCNKYTENDINIYGTKAKGIKGSNLANN
DYIVAFTVAQNNDVLTLLTDDGMIKKIRAKDILYVSKNNRGKLLFKNRKFDPY--I-INEIYDSDVILVRDKEGFTHLDSIKQYSFSKTDD---------
------------
>tr|A0A0D5ZJS5|A0A0D5ZJS5_9MOLU DNA topoisomerase (ATP-hydrolyzing) OS=Mycoplasma meleagridis GN=VO56_01625 PE=4 SV=1
-TDLVKEEQVQIGISRFGYLKRISQKVAESNTMQTYA-----LKEEDYLIRYNTFNTLNNLLIFTNLGNYAIVPIFKISESKWKDLGVHLSEFVNVRPDE
EIVAIYEVDSWDKNLFVVLGSQKGMFKKVALKEFEVSRIKKYTAMPLADNDKIVNATISDNTKDIVIITNSGYVTRYSENDIAQYSPKAKGNKGLYLSLN
DQVANFETLNPDQSLAMLNSDRIFKSIPLTKIPYIPKNIKGKQIFKDFKINEK--TLLWDLTDVLDILAKDDEQKSYLDNLDNIYQKQ--D---------
------------
>tr|A0A0E3KX98|A0A0E3KX98_MYCSY DNA topoisomerase (ATP-hydrolyzing) OS=Mycoplasma synoviae ATCC 25204 GN=VY93_00305 PE=4 SV=1
-LDLVKEEIINVSISKNGFIKRFSDKVLENNEWKNYA-----LKEKDNLVFFSKVNTVNFLLCFTNLGNYVIVAIYQIQEVKWKDLGNNINLFADIRPDE
EIVSVIEVSDFEENLSVMLGTKKGYFKRVMLKDFLVSRFKKYTAMPLNEDDYLIKAKLTNLDSYLVAITENSIISKFSESEIMFYSTKARGSKAIYFSVG
DKLSNFTIVSYGDEIFALSSDLNYFYFNEADIVLTPKNIKGRNIFDKKYKLQNKNYLLFEDT--DFLYFKNTLNE--LNQVKLNHLDKKKS---------
------------
>tr|D4XVG2|D4XVG2_9MOLU DNA topoisomerase (ATP-hydrolyzing) OS=Mycoplasma alligatoris A21JP2 GN=MALL_0620 PE=4 SV=1
-KDLVKEEIVNISFSKNGYIKRLSQKIIDSNSPESYM-----LKEEDNLVFFDKSNTMHNILIFTNLGNYAIIPVYKILESKWKDLGTHLSDFVALYPGE
SIVNVIDVEDWNVGDYVVIMSKQGYAKKTLISDFEVSRIKSYTALKIDKNDEIVNVALSDGTKDILIVTAMGYTSKYNENDLNIYGPKAKGSKAVYLSNK
DYVASFEMVKFNDTVSMLTDDGYFKKMKAKDILYVPKTNKGKEIFKNRKLNPF--F-VTDMFNETEFWIKTETNEILLQSSLGYKLSKNDE---------
------------
>tr|A0A014KW61|A0A014KW61_9MOLU DNA topoisomerase (ATP-hydrolyzing) OS=Mycoplasma ovipneumoniae 14811 GN=parC PE=4 SV=1
-QDLIKDEQFYFWVSKTGLFKKMNIKNHAVEEIEKIQ-----LPSEDFFVFQGKINQRQKGLFLTNKGDVGMLLAHQLEELTLKNNPNNLKISLGLKNDH
ELINSFFLDDLDSNHFLLFITKFGYAKRMQLKEIAKIRPNMINCFKPKEGDELISIFLENKLKNIVLITSQNRALKISVSDVPIYGRISSGVKILKLQKN
EKIVASVLINSSEQIAVIDNYSRFEKIASEKLHFGNRTIAPKSFDSKLDFSII-PK---SVEENLQVFDFDTTLKVIPVQKFI-----------------
------------
>tr|Q4A8X9|Q4A8X9_MYCH7 DNA topoisomerase (ATP-hydrolyzing) OS=Mycoplasma hyopneumoniae (strain 7448) GN=parC PE=4 SV=1
-DELVKDEFFYFWITKSGLYKKLDIKNSLPDEIEKTQ-----LPNGDFFIFQGIINQKQKAVFLTNKGEIAILAVHQIPELNLKNSPNNLKITLGIPNNQ
QILSVFFADSFESSQFLIFISKFSFAKRMNLDQLMKIKQKLQNIFRFKEGDELISVFLEEKLKNIVLITTQNRALKMSISEIPIYTRNSTGIKIFRHRKN
EFISASQTIESSESLAVIDFNSQFEKINTENLFFGNKILTPKNFKTKLDFSLS-PK---SIIENLQIFEFGEGLKIFSLNDFR-----------------
------------
>tr|A0A0A8E6K4|A0A0A8E6K4_MYCFL DNA topoisomerase (ATP-hydrolyzing) OS=Mycoplasma flocculare ATCC 27399 GN=parC PE=4 SV=1
-GDLIKDEFFYFWITKSGLYKKLDIKNSALEEIEKTQ-----LPENDIFIFQDQINQRQKGIFFTNKGDIAIFSAHQIDESNLKSAPNNLRITLGIPNAD
HILSAFFVDNFEDNQFLIFITKFGFAKRMSLEQLAKIRQKLQNIFRIKEDDKFISAFLENKLKNIVFFTTQNRALKISVSEIPIYSRNSSGVKILSLRKN
EFVTASQTIETSDSLAVIDFYSRFEKIDTANLHFGNKKIAPKNFETQLDFSQT-PK---SIADNLKVFEFNKPLKIFTISDFA-----------------
------------
>tr|A0A0C5WWT3|A0A0C5WWT3_9MOLU DNA topoisomerase (ATP-hydrolyzing) OS=Mycoplasma dispar GN=MDIS_00105 PE=4 SV=1
-DELIKDEFFYFWISKSGLYKKLDLKNSTTEEIEKTQ-----LPKDDIFVFQGLVNQKQKALFLTNKGEIAVFPVHQIDELNLKNAPINLRITLGIPNDQ
EILNAFFVDNFENNQFLIFITKFGFAKRMQLDQLAKIRQKMQNTFRIKENDEIVETFLENKLKNIVFFTSQNRALKISLSEIPIYSRNSAGVKILNLRKG
EFIVASQTIETSDSIAIIDYYSRFEKIETDSLHFGNRLIAPKVFSTKLDFSLI-PK---SIAQNLTVFEFDNPLKIFTISDFI-----------------
------------
>tr|C5J6X2|C5J6X2_MYCCR DNA topoisomerase (ATP-hydrolyzing) OS=Mycoplasma conjunctivae (strain ATCC 25834 / HRC/581 / NCTC 10147) GN=parC PE=4 SV=1
-EDLIKDENIYFGITQQGYYKKISLKNFSLSDLDKYA-----IKKDDFLILLTKLNLKDKIFLVTNKANLVVLAAHQLEETSYKNIGNDLKIEVDFQQDE
YIVAQINISENKNNSNIILVSKHGLAKRVSLDSLFNLRTKLTNIFKLKEHDELIGAYLTDNLANIAIISNLNRSLKVAEIDIPIYGRNSAGVKLATLKKG
EQIQLAYPIADGEKIAIIDSWASYEEISNSQITFGARGASLKNLKTKLDFAEF-PK---SFTTNLQILYYDDNIKLYSLADFK-----------------
------------
>tr|W5USV2|W5USV2_9MOLU DNA topoisomerase (ATP-hydrolyzing) OS=Mycoplasma bovoculi M165/69 GN=parC PE=4 SV=1
-DQLVKEEFFFFSISKNGFYKKMSIKTNIIEEISKLP-----VAEKDFLISLDMVSSKDKIFLITNLGNLITLLPHALEESQLKQSGIDLKTKLAFGHKE
YIIAAIPVSNIE-NQSLILVSLAGLAKRVSLDNFANYKHKITNIFKLKDSNELISCHLGENNANIAIFTSLNRGLKVSETDVPIYGKNSAGVRLINLRTN
ESISGTALICEDEKVLIFDHWSRFDQLLPGNILFGQRGSTPKKIETNLDFSKP-IM---SASSNFGIFDFSDLIKIYNINEAT-----------------
------------
>tr|E0TKM4|E0TKM4_MYCHH DNA topoisomerase (ATP-hydrolyzing) OS=Mycoplasma hyorhinis (strain HUB-1) GN=parC PE=4 SV=1
-EELIKNEESYFVITKQGLYKKMSNKVFESNDISNIS-----LKEKDYFVFVNKIQTKNKLLIFTSVGNYIFIPLHTIEDATFKATWSDLQIDYLLKKDE
TIISAIEIADFSENQFVCLITKNGMGKRISLKDLEVSRFKTILAMKIKQDDQLIGAKLSDNYQDIALFTNQNRASRYSEIEVPIYGTNTAGVRILKLKEG
EYIDHFVLGQSDDVFVFVAKSGFVRNISLSSIYYGNKNSQAKFYLES-KFTHLKIV---NIINKEICFIFEEPNKVSKVPSLEIPG--------------
------------
>tr|W6A9T4|W6A9T4_9MOLU DNA topoisomerase 4 subunit A OS=Spiroplasma sabaudiense Ar-1343 GN=parC PE=3 SV=1
-KQTLVEKEYNIWISRDGYLKALE-----PNQIGKFK-----RRPNDLWIANVPATTLQHLILVSSAGVYYSIPVFKINSSKWKETGMHINQIATMNGNE
KIIAAFVVNSFENKQEILVASQNAMIKRTPVESMVTKMFKAFKIMKLSDGDRLVSASLVTSTKFVTMVTQNGFSVRYDIEEIPSASVTAKGVKSCSAKDE
KIIAGKAFD-N-EDIVIITNKGNIKKIKPEMIPLMNRPKKGVRLYPWNKKRDEFVLDLFSA-NET-LCLLDEEDNLKQLNVNTLKYSDLEE---------
------------
>tr|W6A7M1|W6A7M1_9MOLU DNA topoisomerase 4 subunit A OS=Spiroplasma culicicola AES-1 GN=parC PE=3 SV=1
-KKTIVQKNYTIWISQDGYLKAIE-----DSQLGKFK-----RKPNDIWISQVPASSLDFILLVSSAGTYYSIPVYKIIPSKWKETGMHINKVATLTGQE
KILAAFVVHEYKNKQEILLATKNGMIKRTPVEDLETKMFKSFRIMKLAQGDEVVSASLVSSTKTVTMLTKTGFAVRYDITEIPSAGPNAKGVKSTVVKDE
DIIAGKAFA-S-GDVLILTNKGNVKKIKQDLVPIMARPKRGVRLYPWNKKRDEFATFLYNV-KDI-LNILDEEDKLTQLNVKNFKYAELED---------
------------
>tr|S5M1Z3|S5M1Z3_9MOLU DNA topoisomerase 4 subunit A OS=Spiroplasma diminutum CUAS-1 GN=parC PE=3 SV=1
-KKTIVQKDYTIWISQDGYLKAIE-----DSQLGKFK-----RKPNDIWISQVPASSMDFILLVSSAGTYYSIPVYKIIPSKWKETGMHINKVATISGNE
KILAAFVVKEFKDKQEILLATKKGMIKRTAIEDLETKLFKPFRIIKLQQEDELISASLVTSTKTVTMLTRTGFAVRYDIAEIPSAGPNAKGVKSTVVKDE
DIVAGKAFA-N-GDILIITNKGNVKKIKQDLVPIMSRPKRGVRLYPWNKKRDEFATFLYNV-KDI-LNILDEEDNLTQLNVKNFKFADLED---------
------------
>tr|A0A0K1W144|A0A0K1W144_9MOLU DNA topoisomerase 4 subunit A OS=Spiroplasma litorale GN=parC PE=3 SV=1
-KKTIVEKDFTIWVSQDGYLKAID-----DSHLGKFK-----RKPNDIWIAQFPASSLDYILMVSSAGTYFSIPVYKINPSKWKEIGMHLNEVATISGNE
KILAAFVVKKFNGKQEILLASKKGMIKRTPIEDLETKMFKAFRIMKLQDGDELVSASLVTSTKVVTMLTKNGFSVRYDISEIPSAGQNAKGVKSTVVKDD
DIIAGKAFEEK-GDILILTNKGNVKKVKQSLVPLMSRPKKGVRLYPWNKKRDEFATFLYNV-KDV-LNILDEEDNLVQLNIKSFKYADLED---------
------------
>tr|V5RIJ3|V5RIJ3_SPIAP DNA topoisomerase 4 subunit A OS=Spiroplasma apis B31 GN=parC PE=3 SV=1
-KKTIVQKNYTVWVSQDGYLKSIE-----ESQLGKFK-----RKPNDIWISQFPASSLDFILLVSSAGTYYSIPVYKITPSKWKEIGMHLNKLATLSGQE
KILAAFVVRDYKNKQEILLATKKGMIKRTPVEDLETKMFKSFRIMKLAEDDELVSASLVTSTKYVTMLTRTGFSVRYDISEIPSAGPNAKGVKSTVVRDE
DIIAGKAFD-S-GDILILTNKGNVKKIKQDLVPIMTRPKRGVRLYPWNKKRDEFATFLYNV-KDI-LNILDEEDNLTQLNVNTFKYADLED---------
------------
>tr|N9UAJ0|N9UAJ0_9MOLU DNA topoisomerase (ATP-hydrolyzing) OS=Mycoplasma alkalescens 14918 GN=parC PE=4 SV=1
-KLLAKNEDFYFFVSQEGYIKKISNKIFLANELSSYK-----LKEDDAIKYYDKINSLSKLLFITNKGNFFVLEAHIFKDNSWKELGVHISSLVNLDFNE
KIICVMEITSFNTYLNLILITKFGYAKKVKISAFESKIFKKRSCMNFKNDDELVDAKISNDEKDLFILLNNGLYFLISEDVFSDLALKAQGIKLLPKLDK
THVAAFCICSKFNQVIMLTEDGLLKQWDIGEIAYTNRTNRGTFLFNLLKNYNCSPK---SFEKQLEFLFTNKSNEVTQFDLNELDKDHSKN---------
------------
>tr|N9TQU1|N9TQU1_9MOLU DNA topoisomerase (ATP-hydrolyzing) OS=Mycoplasma auris 15026 GN=parC PE=4 SV=1
-KSLTKNEDFYFFFSQDGYIKKITPKIFNSNDLSSYK-----LKNDDAIFYYNKINSFSKILFFTNKGNFFILEAHILKDNIWKELGIHISSYINLDINE
KVIRIMEVSSFDNYLNLIMITKLGYAKKIKFSDLESKIYRKRSCISFKNDDELVDIKIGNDEKDIFILLNNGLYFLINENEFSTLTLKAQGIKLLPKLNK
TYVAAFATVSKFNKILMLTQDGLTKIWNASDLAYTNRSNRGTFLFNVLKNVNCIPK---NLENNLEFLYTNKNNEVTEFNLNNIENSNKRI---------
------------
>tr|A0A077L6W1|A0A077L6W1_9MOLU DNA topoisomerase (ATP-hydrolyzing) OS=Mycoplasma canadense GN=gyrA PE=4 SV=1
-KLLAKNEDFYFFISEQGYIKKISNKIYNSNDLNTYK-----LKENDTIKYYDKINSLSKLLFFTNKGNFFVLEAHILKDNSWKELGQHISSFVNIEANE
KIIRVMEITSYNSYINLILITKYGYGKKVKIINFDSKTLKSKTCISFKNDDELIDAKISNDEKDIFIILNNGSYFLINENIFSDLALRAQGIKLLPKLQK
TFISAFTTCSKINKVTMLTEGGMFKQWNMSEIEYTNRTNRGSKLYNFLKNVNCIPK---CLEKELELLYTNKNNESSIFKFEKMTKDKTKN---------
------------
>tr|D1J8U9|D1J8U9_MYCHP DNA topoisomerase (ATP-hydrolyzing) OS=Mycoplasma hominis (strain ATCC 23114 / NBRC 14850 / NCTC 10111 / PG21) GN=parC PE=4 SV=
-KLLTKNEDFYLYITKDGYYKKISLKVYTSNELSTFK-----LKEEDNVFYFDKVNSLSKILFFTNLGNYFIIDCHLFKDCNWKDLGQHISSIVALESSE
KIIRVIEITSFNNYANFILMSKLGYAKKVNLRDFENKSSKTKTCMSFKDNDELIDAQISNDEKMLFILLNNGMYHLVSENELKGISLKARGIRLLLNLYQ
LQVSGFITVSKYNNIIYLTQGGYIKCWDTSKLESTTRNTP-KMLFTPLKNNILGLQ---SLASNLKMLYTDNNGNLAEYDWKFILKDKTKE---------
------------
>tr|A0A0C6G4G6|A0A0C6G4G6_MYCAR DNA topoisomerase (ATP-hydrolyzing) OS=Mycoplasma arginini GN=gyrA PE=4 SV=1
-KLLTKNEDFYFFVSEEGYIKKISNKTFNSNDLKTYK-----LKENDTIRYYDKINSLSKLLFFTNKGNFFVIEAHNLKDNSWKELGTHVSSIVNLESQE
KVIRIMEITSYNSYINLILISKYGYGKKVKISNFDSKIFKKRICINFKNDDELIDVKIGNDEKDIFILLNNGSYFLLNENIFTDLALRAQGIKILPKLQK
TFVSAFTTCSKLNNVTMLTEGGMCKQWKMADIEYTNRTNRGTKLFSFLRDISCIPK---SLEKELELLITNKDNETERLYLDKLLKDKSKK---------
------------
>tr|Q98QI8|Q98QI8_MYCPU DNA topoisomerase (ATP-hydrolyzing) OS=Mycoplasma pulmonis (strain UAB CTIP) GN=MYPU_3730 PE=4 SV=1
-EELVVDEKCYVSLSQDGYLKRVSSKTFKTNDFASFG-----LKENDNLSFLSKATTKDKLLIFSDHGNYAIIPIYKIEEQKSKSFGVHINDFVYFNSYE
KIIYVLVVNEFSQDYYISLVTQKGLGKRVSLNKFLITRQKISNAITLKDDDRLVDVRVSKGKQNIILFTNFNNVVKFSEDALPVISTKGQGNKMIQLSEG
EKVSAMSITKTTDNLILITNKNNLIKVPTSHFKFTPRAAKGKRISEELKLGYQKIVLAYN--HHKLILVKNELEKIDPSKIVNFKITK------------
------------
>tr|B3PLT5|B3PLT5_MYCA5 DNA topoisomerase (ATP-hydrolyzing) OS=Mycoplasma arthritidis (strain 158L3-1) GN=parC PE=4 SV=1
-KLLAKNEDFYFFLSKEGYIKRISKKAFSSNGFSGFK-----LKDNDAIFYYDKINSLSKLIFFTNLGNYFIIDAHTLKENGWKDIGNHISSLVALENNE
RIIRVMEIESFNTYSRFIILTKKGMAKKVEIQEFDSKQIRKRSCIPLRPNDELCDVRIVNKEKLLFILLTGGLYYLIDENVVPEYSLKASGISLIKTDRD
QEIEAFSPISPN-KVIIMTDKGQFKRTKMETVKLVGRSSHGKVFYYPMKTVSSKVI---SLETQLQCYFTNKENEPTKFDLKNIPLSKQQD---------
------------
>tr|A0A063YD12|A0A063YD12_9MOLU DNA topoisomerase (ATP-hydrolyzing) OS=Mycoplasma hyosynoviae GN=NPL1_01830 PE=4 SV=1
-KLLAKNEDFYFFISEQGYYKRVSIKTKKSNEFNTYK-----LKENDAIFYYCQINSLSKLIFFTNLGNYFLIDAHILKECGWKDLGSHISSLVALDTNE
KIIRVMEIASFRTYVNFIFITRLGMAKKMSLEEFKDKQIRKRTCMPLKPDDLLVDVKISNAEKMLFILLTGGIYYFIEDRIISEYSSKASGINLIKLENG
LEIEAFHTVRPADRIIIYTDQGQFKRVKASKIKPVGRSSRGKIFYFPTKTVKSKVI---GIEKELVYLYTNGDNEPQKFDYKTIAFSDLKD---------
------------
>tr|G4ENR9|G4ENR9_MYCIO DNA topoisomerase (ATP-hydrolyzing) OS=Mycoplasma iowae 695 GN=GUU_00402 PE=4 SV=1
-TDIIEENHGVCIVTRDNYIKYIKDISITDVTLDKFK-----FKEGDIPVNMISLSTLETLVCLTSKGKCITIPAHKIKFTKAKDNGIHINEIITIDSFE
KTIAIFAISNSNI-TEVFVATKNSLVKRFMIEDLTMARNKISSYIGLKSDDEVITAFVVKDYKEVITVSKNGNGLRYQINEVPVVGRSASGVKNINLKDD
DCVALMPVEP-DESFILLISNRGAKRIHFEDITLTSRAKIGKRILSQ-VESNPYIHSGFMIGRE-TIYLLDGNNKLHEKKVSDIPITDFTT---------
------------
>tr|A0A061FQV0|A0A061FQV0_THECC DNA gyrase subunit A OS=Theobroma cacao GN=TCM_044582 PE=3 SV=1
-IDVIPNEEMLLAFSEKGYVKRMKPNTFNLQNRGTIGKSVGKLRFNDAMSDFIVCRAHDHVLYFSDKGIVYTARAYKIPESSRTAAGTPLVQIISLSEGE
RITSIISVSEFAEDQFLAMLTVNGYIKKVSLNYFSAIRSTGIIAIQLVPGDELKWVRCCINDDLVAMASQNGMVILSSCGIIRALSRNTRGAIAMRLKEG
DKMASMDIIPAGPWLLFVSENGYGKRVPLSSFKRSPLNRVGLIGYKFSS-E-DRLAAVFVVGFDEQVVLVSQSGTVNRIKVRDISIQSRYARGVILMRLE
YAKIQSAS----
>tr|W6TY93|W6TY93_9SPHI DNA gyrase subunit A OS=Pedobacter sp. V48 GN=gyrA PE=3 SV=1
MEDFIEDEDVVITISHEGYIKRTPATEYRTQGRGGKGSKGSDSRNEDFIEHMLIASNHNYMLFFTETGRCFWLRVYEIPEGSRLSKGRAIQNIINIPKEE
KIKAFIKVKNYLENNYIIMCTKKGTIKKTSLEAYSRPRVNGINAININEGDQLLEASLTTGTSEIVMALRSGRAIRFNEEKVRPMGRTATGVRGVTLAHN
DEVVGMIAVNDGATVLVVSEKGYGKRTDIEDYRVTNRGGKGVKTINVTE-KTGALVAIKNVTDADDLMIINKSGIVIRIVVSELRVMGRATQGVRLINLK
GNEIASVARID-
>tr|A0A077ZE75|A0A077ZE75_TRITR DNA topoisomerase 2 OS=Trichuris trichiura GN=TTRE_0000613401 PE=3 SV=1
TEVLIAQEDVIVTLTKEGYLKRSSLRSYNASRPDEHG-----MKDGDSIIFINKLNTLDHLLILTNHGNMIYRPVHEITELKWKDVGEHISQTITLSMSE
EIIAAFPYKEIDANKLFIFMSKEGMIKQTRMTEFSPWRTYRTTAMKLKDTDEIVSVFLTTRNVDVFIASHRAFGLRYPLEEVPVVGSKAAGVKAINLKDG
DYVVAGALVPSDSPILLLSQRGAAKRMLAQELPQLGRAKRGLMIFRELK-KNPHRLAYMTAETEGKLTLTTTKGIEKEIEISKVAISDRISNGTFAIDEK
QEELFSVMQ---
>tr|B1BBK7|B1BBK7_CLOBO DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium botulinum C str. Eklund GN=CBC_A1648 PE=4 SV=1
EDIKIEDFNPTLVLTEQQYIKKNRVFS----------------KDDDKILQFHQCNNKDDLLLFTNKGNVLIRKVYELDEHKPSTYGDFLPNLLGHLEND
EKV--IYITTKNYKGSVITVFENGNVARIDLKQ---YKTKQVPMDA-YTDSKLVSISVITDDTNILLVSQEGKALIINTSIRPTKSRNTQGVAGMKIDTE
HNKIGSIIGVTDNFDI-KTEKSKSKFIMLDDIAPNGKQS---MTEYLK--------------------------------------GNRNTQGNFIYNTR
QKDKVIELI---
>tr|A0A0L7NFE4|A0A0L7NFE4_CLOBO DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium botulinum GN=ADU76_04515 PE=4 SV=1
EDIKIEDFNPTLVLTEQQYIKKNRVFS----------------KDDDKILQFHQCNNKDDLLLFTNKGNVLIRKVYELDEHKPSTYGDFLPNLLGHLEND
EKV--IYITTKDYKGSVISVFENGYIARMDLQT---YKPKQIPMSA-YTDSGIVSIQLITNDTDILLVSQEGKSLIINTSIRPTKSRNTQGVSGMKIDIE
TNKIASIIGVTDNFNI-ETEKGKSKFIMLNDVAPNGKES---MTEYLK--------------------------------------GNRNTQGNFIYNTR
QKDKVIKLT---
>tr|A0A077ZFT4|A0A077ZFT4_TRITR DNA gyrase subunit B OS=Trichuris trichiura GN=TTRE_0000757301 PE=3 SV=1
DEDLIEEEDVVITLTNNGYIKRVASTEFRSQRRGGRG-----VHDDDFVKTLISCSTHDTLLFFTNSGRVYRAKGYEVPEYGRTAKGIPIINL-LIDSNE
TIQAVISVGQAEDGHFLFFVTKKGTVKRTTVTAFSNIRANGLIAIGLREGDELVNVMSTEGDETIIIGTHDGYSVTFKEAVVRDMGRTASGVRGIRLRDE
DYVIGSAVLKE-QEVLVITEKGYGKRTKASEYPVKGRGGKGIKTANVKE-KNGPLAGLTTVTGDEDILLITDKGVIIRFNAGSVSQTGRATLGVRLMKME
GNKVVTMAI---
>tr|Q5CB96|Q5CB96_9THEM ATP-dependent Clp protease, ATPase subunit OS=Thermotoga sp. KOL6 GN=clpA PE=4 SV=1
MEELIAEEDIVITLSHKGYLKSTPLSSYRSQRRGGKGITVSKLSEDDEVEFVVVTKNISSTLFITNLGKAYVLKNYQIETTGRNTRGRHISAFLNLEETE
KVVALAPLNG--KGKDLVIVTKHGKIKRTALEEFENATSRGVRAIRIEAGDEIISARVIDSRGSLVVATKLGMVIRFPVSDVRRMGRNAAGVQAIKLQPD
DEVVSMDVVPSEGEILTVTEKGFGKRTPVELYRIQKRGGTGLRNISDVK-KTGYVVAVRYVRGDEEIVVVTKNGMMIRIPVSDIGIIGRITKGVKLIELG
DDSIS-------
>tr|K1ZW59|K1ZW59_9BACT Topoisomerase II subunit A OS=uncultured bacterium (gcode 4) GN=ACD_64C00294G0001 PE=4 SV=1
-ADLIPDEEVVVTLTVKGYMKRVLLSTYGVQHRGGKGKMGMVSLSDDVMQDLFVTKNHDTLLFFTNSGRIYSLQVFEVPEASRMARGRAVVNLLPLQPGE
KVVKLLCAREL-EGKFLVMLTKNGIIKRTDASDFAKIRSTGIRCTTLREDDELVFCSLSSGADTIVIASAHGQGIRFKEEEVRAMGRQAAGVIGIRLRKG
DFVVGMEIIGIAGDILFATENGYGKKVRVEDFRVAHRSGLGVRTIPTDT-RNGYVIGLAIVHPDSNILLIDQAGKIIRLPASEIRTMGRQAKGVRLVRLD
SGKLASIFAF--
>tr|A0A0K6LA48|A0A0K6LA48_BACCE DNA topoisomerase 4 subunit A OS=Bacillus cereus GN=parC_1 PE=4 SV=1
---MIPQEDVIVTVTKEGYVKRTGWRSHNASNGKDFG-----MKEGDILLERFDTNTTETVLLFTNKGNYIYLPVYEMPDIRWKDLGQHVANIVSLDRDE
TIIWATVVPNFEEERFIVFVTKNGMIKKTELNQYKVQRYRAFVAVNLKKDDEVVDIFATDGTSDIVLATHGAYALIFHEDEVSPVGVRAAGVKAINLKED
DYVASGKPLNAKDQLILVTQRGAVKRLKASEIEKSTRAKRGLVIFKELKRNPYRIVGIEIVRDDELVYMKTEKHIVEEIDPKAYRNKDRYSNGSLVLDVN
DTEVIET-----
>tr|A0A0D7XCH6|A0A0D7XCH6_BACAM DNA gyrase subunit A (Fragment) OS=Bacillus amyloliquefaciens GN=UZ38_33700 PE=4 SV=1
---MVASEDVYVTVTKDGYIKRTSQRSFAASNGQDFG-----MKDTDRLLCQLEMNTTDVLLLFTNKGSYVYCPVHQLPDIRWKDLGQHITNIISIDSDE
SIVKAIPVREFTESEYLLFFTKNGMAKRTQLMQYKAQRYKALVALNLKGDDEVVDVHVTDGTKDLFIATHSGYGLWFSEDEVSVVGARAAGVKGVNLKDG
DFVASGQ--VLSDVLVLVTQRGSIKRMNRTEFEKTSRAKRGVLMLRELKKKPHRITGLLACSYHAQITLQTEKGITEEMLVKDIKLHDRYSNGSFIIDED
EAEVTDV-----
>tr|T0NXK7|T0NXK7_9BACI Uncharacterized protein OS=Geobacillus sp. A8 GN=GA8_03610 PE=4 SV=1
---LIPAEDVIVTVTKEGYVKRTSYRSYSASNGQDMG-----MKETDRLLAQLEMNTTDVLLLFTRRGYYLYCPVHTLPDIRWKEVGHHISHLIPLERDD
ELVAAVPVSSFNTGEQLIFVTKQGLVKRTELAQYQVQRYRPLVAVNVKEDDDVIAVYATDGCGHLWLATHDGHALLFAEEEISLVGVRAAGVKGIQLKEG
DFVAAACPVRLGGSFVVVTQRGAVKKVAMSEFEPSSRAKRGVVIVREVKSNPHRVVGAVFVSSEEMVGLRTEKGVVETIEAASLRLSDRYSTGSFVVDTD
EAMVVDV-----
>tr|S2PRS5|S2PRS5_LACPA DNA topoisomerase IV subunit A (Fragment) OS=Lactobacillus paracasei subsp. paracasei Lpp123 GN=Lpp123_06200 PE=4 SV=1
----------YGAGSRDGTLNDSSLRSYQAVDPADNG-----LKANDLAIFTGELSTLQHLYIVTNAGNVIYRPVHEISDARWKDTGEHLSQTVGLGTDE
KVLAVFAFDQLDGAGSFVLGSSDGYIKQTALSDLQPQRTKPMMAMKLKD-PAAIAYFTTDQQQDVFVVSRHAYGLTFPLNDVSTVGARATGVKSMDLKPD
DEVVNFIP---TAKVGILTQRGAFKKMALSEVGEMSRARRGLLVLRELKRDPHRIVAMMSV--ATRLNVLTDTGKVTTLNPAQHPAGDRYSNGSFVIDTD
VLKPVFV-----
>tr|A0A0G9GHN4|A0A0G9GHN4_LACPN Uncharacterized protein OS=Lactobacillus plantarum GN=WP50_36745 PE=4 SV=1
-------------------------------------------------------------MMFTNMGHLIYRPIYEIADAKWKDTGEHISQTIGLAENE
RITWVYSFENLKATGKFLVATSDGYIKQTAFADYTPGRTRASQFIKMKSDDATVEYLPAAPTGTLILITQHGYGLRYDLSEVPTIGAKAVGVKSMDLRDD
AIVRATI----DDLIAMITQRGSFKKMKVADLPVTSRARRGVQVLRELKNNPHRVADYVLVASGVALDVLTDRGKHHSILNDDHPTSARYSNGSFVVDTD
TEEPVSM-----
>tr|E1NMF9|E1NMF9_9LACO DNA topoisomerase IV subunit A domain protein OS=Lactobacillus iners LactinV 03V1-b GN=HMPREF9212_1408 PE=4 SV=1
---MLSEEDVRVLVSANGYLKRSSLRSYQSTDSADNG-----LPSGDEVIFDKTVSTLSNLYIFTNKGNLIYRPVYELVDTKWRETGQHLSQEIVLTNDE
RIISVFDINNLNSDLIFLITTNDGYIKQVALSDLQPTRTRAIMVIKLKDDHSNVEQLKSGSDNEILLVTNSAYALRFDVNEVPLVGPRAAGVKSINLKND
DDYVVSAPECLSLKLGIVTQRGAFKQLQVDLVNKFTRAKRGSMILRELKTKPHRIVAALIYTQNHDINIKTSSDRTIKIRTNDYPVGDRYSNGSFVVDTI
SDVPVAL-----
>tr|R4RWP4|R4RWP4_LACFE DNA topoisomerase IV, A subunit OS=Lactobacillus fermentum F-6 GN=LBFF_0954 PE=4 SV=1
---TVADEDVIVLVSAAGYIKRSSIRSFKASEVGDNG-----LREDDYPLLLEQTTTLSHLYMFTNQGRFIYRPVHELTDARWKDTGEHLSQTIDLDDDE
VIVKAMLLDKLDLPGTFIFATSDGQVKQSALSDYQPGSRHASVAIKLREG-AQVDYFEPEAGQSVLAISREGYALRFAVEDVPVTGVRTAGVRAINLKED
DQLVGIS----GDHLGLVTQRGAFKEMAVSDLEVGARARRGNLVLHRLKKNPHQVVAFVTHPATGALEIITNRPAFQDVLVAEQRLGTTQSNGSFVVDTD
TQVPVTL-----
>tr|D8TXP4|D8TXP4_VOLCA Putative uncharacterized protein OS=Volvox carteri GN=VOLCADRAFT_91671 PE=4 SV=1
LESLVPPKPCLVLASRRGFLRRLAGDSLTAQNRNTRGKSGIRLRSGDQLASLVAGSDRDLLMVVTPDGRMFKTRTAAVPPSSSSASSASPTAAAASGGTE
SVGRMKEVEDAGAGPCLVLCTRGGRIKRLALKNRRES-KKGIMVMGLESPDEAGEEELCWPGDVVVVASAEGQVLLFPATDVRVSGPQSAGTHAMRMSKR
RPNDRIADIREGPCLLLVTAHGIGKRIPLGQLRLGMRRQAGMVAIRVASAEARQRSRRSSSGDGEEVIMASRNGVVVRQSVDGIAVQGRMTRGTFVMQLD
GGEVVDVVAAA-
>tr|W6W443|W6W443_9RHIZ DNA gyrase subunit A OS=Rhizobium sp. CF080 GN=gyrA PE=3 SV=1
DEDLIAREDMVVTVSHLGYIKRVTLGTYRAQRRGGKGRSGMATRDEDFVTRLFVANTHTPVLFFSSRGIVYKEKVWRLPIGTPQSRGKALINMLPLEPGE
RITTIMPLPEDEENLDVMFSTTRGTVRRNKLSDFVQVNRNGKIAMKLEEGDEILSVETCKPGDDVLLTTALGQCIRFPVDDVRVFGRNSIGVRGISLGEG
DRIISMTIVREEQFVLTVSEKGFGKRSSSYDFRTSGRGGKGIRATDTSKTTIGELVAAFPIEDNDQIMLVSDGGVLIRVPVNGIRIASRATKGVTIFSTA
KDKVVSVERIS-
>tr|C1N3Z1|C1N3Z1_MICPC Predicted protein OS=Micromonas pusilla (strain CCMP1545) GN=MICPUCDRAFT_52348 PE=4 SV=1
IPLDSLDADNLIVMTGKGYIKRIDPKIFSRQNKGTIGKKGGRMRGGDQVTKVTHCNGLDTVLFFTDRGRVYAVRAYDIPQSSTTALGTPFTRVLKLAEGE
TITAMLPVDTASVGEHLVMLTARGVVKKTPISEFANINRAGKRALGLQKGDRLKHVELVRDGDGIMVAGVDGMVLHFSMDSIRAQSRIGSGVKAMKFREA
SAGATEKKPKSGAMVLLVTSEGQGKRISVGQFRQKGRGGLGNKAIGLEEGS---RLAAMCITVAEEVIIGSTAGVLNRYDVTELPQLGRNAKGVKLMKLN
DGTVRDITLLP-
>tr|E1ZRV4|E1ZRV4_CHLVA Putative uncharacterized protein OS=Chlorella variabilis GN=CHLNCDRAFT_56398 PE=4 SV=1
HEDVIPNAPSLVVYSRRGYIKRVRPDTFGAQKRGGVGKAGARLKEDDSLDEVVYVNDHDHLLFFTTEGRAYSLRAYDVPEGTRTAVGSAVTQVLPFDKST
RIAAMVPVSGFGAEQDVVMLTRKGQIKRTALKQFTSINRSGLVAMGVREGDSLQFVGLCSPTDSVLIAASNGSAQHFAITKLRRMGRAAVGNKSMTLSKG
TDIVAMA--EEGPYLLLVTQQGLGKRTCISEFRLRARTGSGIQALRLNLGD---RLAAVQDEAGADVVLSTQQGQLVRVPVADVNIHSRFAKGHRLVKVR
QGEVVAATVLS-
>tr|C1EGN9|C1EGN9_MICSR Uncharacterized protein OS=Micromonas sp. (strain RCC299 / NOUM17) GN=MICPUN_88167 PE=4 SV=1
VTLDMLNSPSLVIMTNRGYIKRIDPAVFSKQNRATRGRNMGKMRGGDEVTKVTHCNGLDTVLFFTDRGRVHAVRAFNIPQASTSALGTPFTRVLKLAEGE
SITAMLPVDTTEGETSLCFVTARGLIKRTCASEFVGIRNNGKKALVLRKGDRLKHVDIVKKGDGIIIGGIDGSVIHFDADSVRAQGRAAAGVKAMAFKPD
GLDDTSED---GPMLFFVSSDGRGKRISVAQFAQQSRAGRGKKGMGLMKGS---KLAALCLT-HEHVIIGSQGGVMNRYDVASIPQSGRAAKGVNVMKLS
DGTVRDITLLP-
>tr|K8F2L0|K8F2L0_9CHLO DNA gyrase subunit A OS=Bathycoccus prasinos GN=Bathy12g00470 PE=4 SV=1
VEHEIPNNDSLIIMSSRGYIKRTRPETFKAQRRGTRGKSMSKLKGSDSIAKVMHAKDLDRVFFFTDKGNVLTVRAFDIPEASTTAQGTPFTRFVDIDKGE
SITAILSLEPSADETFLVMITLNGVIKKVSAKEFASIKRNGKRAIALDEGDKLKQVLVAKNGDSVLVGATDGTLIRFDVDSVRKLGRMSRGVRAISLKEI
KSSSKEASKQ-GPWVVFVSEKGRGKRVKVSDFKTQIRGGAGIRGIKFNSGD---SLAAFALIIEEAIIVGSQLGVANRFQCASIPEMGRYAKGGTLMKLK
KEAIKSFAVIP-
>tr|A0A0P6YIQ4|A0A0P6YIQ4_9CHLR Uncharacterized protein OS=Levilinea saccharolytica GN=ADN01_06125 PE=4 SV=1
---------QLLTISQQGVVKRTERHLFSRQHRGGMGVFDLEVQPPDQPAALACLTAAQHFLVFTNHGRVFRFASGKLELSPVRSRGEDIFDRIPFEAGE
AVAAILPER---AQGYVAMVSASGRVRSLRHHLFGEHMKPGVSVLNFQEYGPLASACWTSGDGDIFLATNNGMGIRFNEKLIPPQ-----GDWGIRLAEG
AQVVGIAPVYDDSRLFLLGADGRGTVRVMPSFAAKSLGGSGKQTIK-----NAQVVGIAALERNQDLFVLSRLGKLIRFPANEVSETEGVVQGVLCMSLR
GDEVVALL----
>tr|I0I412|I0I412_CALAS DNA gyrase subunit A OS=Caldilinea aerophila (strain DSM 14535 / JCM 11387 / NBRC 104270 / STL-6-O1) GN=gyrA PE=4 SV=1
---------NLITVSAGGYAKRTPRHLYSRQRRGGMGVFDLEAPAGDAPAFLAMAEAGDSLLLLTNQGRIFRVAVGEIPEREVRSKGEPLLARLPMRSDE
RLAVVLPDR---SAAFLVVVTERGQVRRIARQYMGASLQPGVVLLDPREGGAPAAACWSSGADDLFLVTRAGLAIRFAERLAPMR-----GCLGMRVDPG
DRVVSVVPVKPEGGVFLLSEDGKGTIRLMSGFSAKSPGAGGKVAMK-----AKAVVGATAVDEESDIFIISRLGKIIRFRAEEIPAKEGAVQGVHCMALR
ADECVALV----
>tr|A0A0P6XDR3|A0A0P6XDR3_9CHLR Uncharacterized protein OS=Ornatilinea apprima GN=ADN00_00350 PE=4 SV=1
---------NLVTFSQKGAVKRTNRGEYTRQRRGGIGVFDIETDQNDHPTLVVIADEPHTLILFSDHAKAYRLPVTKLEAHQIRSKGEYLSSKINLTPGE
TITAALPEQ---AAGYIALISKSGKVRCLRHHLFGEHMKPGTAMYKFEDFGPLASVCWTTGDADLFVVTRNGMGIRFSEKIVNPQ-----GTQAIKLSDG
DEVVSVVSVNEDDGVLVIGADGKGTIRLMSGFAPKSAGGSGKIVIK-----SDKVAGALLAEADADIFLISKLSKIIRFHISDVPETTGVVQGVNCMSLR
ADEVIAIA----
>tr|S6D9D6|S6D9D6_9EURY DNA gyrase subunit A OS=Halorhabdus tiamatea SARL4B GN=HTIA_p2924 PE=4 SV=1
--GLISSQNNVYIYTRSGLCKRTELSEFSRQRRGGKGVICCEVDAEDAVEKVQLTDPRKQLLVLTNHGLIHQVKANQIAPKERTEPGEQIHEFLDFDPDE
RIQAILPIETISEGLFLTLATSDGHVKRTATTEFSNIHRGGIQAVELEGDDRICDVTLTNGSMDILLGTNQGRVIRFDETEAREMGRPARGVHGIELAAD
DHVVGLTTVEPDEEILTVTANGYGKRTAVDEYRTQSRYGSGLLDIVTD-DRNGPVVDITRVQPTHDIVLASGDGQLIRIGADDISRLGRNTQGVQVMDLD
DGRVSGVATC--
>tr|K2DRU8|K2DRU8_9BACT Uncharacterized protein OS=uncultured bacterium (gcode 4) GN=ACD_34C00040G0003 PE=4 SV=1
--------------------------------------------------LLVPARTLHTLLFFSDRGKVYSEKVYQIPDANRTDRGIPIVNVLAMDPAE
RITAAVSVPNFENGSCFTMATVNGRVKRVQLSEFSSVRPSGLIAMNLDENDKLGWVKLTTGKDEIIMVTRRGQALRIKESSIRTMGRQAAGVTGINLKPG
DKLASMDVIEPQGKLLVVTENGFGKCSRLEEYPTKGRATGGVATIKSLP-KIGEIADARVVQDDDDVTMISSGGIMLRLKVKVISMSGRSTRGFKVMDLK
DSIVASVARMA-
>tr|F0V2P8|F0V2P8_MYCS3 DNA gyrase, subunit C OS=Mycoplasma suis (strain KI_3806) GN=MSUIS_00270 PE=4 SV=1
----------LLIITNKGKIYRTQANQLLRVKKENKLLQLQHVSSDEQIIKIINVEPLDFLFLASKDGMIKKIKMMNFQNASKSGG-----IVMGLQGED
EVVSA---LIVRDADEILLTSSFGRVVRFKSIDLRDVTAMGVRGIKLVNSKGEEGELISASSKEVFVLTNLGKGKWVYIDHFRMTSRGVAGVLSQK-GYG
FS-FTININNPLEEIFMLTNLGKVSRIPVNAVSQRGRATSGVSIMKLNHSRNEKIVHCFKFIGVKQ----------------------------------
------------
>tr|I7BB22|I7BB22_MYCHA DNA gyrase C-terminal domain protein OS=Mycoplasma haemolamae (strain Purdue) GN=MHLP_04575 PE=4 SV=1
----------LIAVTNAGKVFKMSTRELI-ISPG--LLSVQNLGYDEHLVKFIYMDEHKCLLFCTKYGIVKKVPIAEFKHVRAIGK-----IAILLKGND
SVRFV---NKVSESDEILLASEEGLAVRFQSNELRKTLSSGVKGIKLTPDTGEISSS-TT--LKVFVVDEQGTGKLTDIDKFKLTVKAVRGVIAYKLSD-
KL-IACTLIKGDEEIVFLTNKHNVLRLPVSEIAERSRICGGVRLIKLDEG--EKVMLCAKSAAEKT----------------------------------
------------
>tr|X1HF53|X1HF53_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=S03H2_43147 PE=4 SV=1
----------LLFFTNKGRLYWLKALEIPDVGVSGRGKPINNLLQEEKVRSIVAVKDSGYVVMITSKGRMKKTRLSGFRNIRRGGI-----IAIGLSRKN
ELLTA---KLTDGQRDILIGTKLGKATKFKESQIRPMQAAGVKAITLRPKDEIIGMIVVGE-EYVFTASEKGRGKKTKINLYPLHRRGGKGVINLIVRMG
KA-IGMVGI-SDEELLLITQIGKVIRIKTGQVRPSGRATQGVKIINLKKGDR--VVSMAKVRET------------------------------------
------------
>tr|A0A0B4U4N5|A0A0B4U4N5_9ENTR DNA gyrase subunit A (Fragment) OS=Dickeya solani GN=gyrA PE=4 SV=1
----------ILCFSSRGRLYWMKVYQLPEASRGARGRPIINLLPNERITAILPVREEENVFMATASGTVKKTALTEFSRPRSAGI-----IAVNLNEGD
ELIGV---DLTDGSNEVMLFSAEGKVVRFAESAVRTMTATGVRGINLQNDDRVVSLIVPRGEGDILTVTQNGFGKRTAVTEYPVKSRATKGVISIKVRNG
KV-VGAVQVDSADQIMMITDAGTLVRTRVSEVSIVGRNTQGVTLIRTAEDEQ--VVGLQRVAEPV-----------------------------------
------------
>tr|A0A0G0XAH1|A0A0G0XAH1_9BACT Gyrase subunit A protein OS=candidate division WWE3 bacterium GW2011_GWC1_41_7 GN=UU77_C0003G0010 PE=4 SV=1
----------AFFFTNTGKVYKLRIWDIPESSRTSKGTALVNFLNSEKVQTFLNINANGFVSFVTEKGQVKKTSLEEFANIRSSGI-----LAIKLSGDD
YLTWV---GLTEGSDDLLLTTSMGQSIRFSEKDVRAMAAAGVTGIRLSKKDDYVVGTVIIPHIALMVVTGKGYGKKTPVSEYKVQNRGGSGILTYKVKTG
KL-VTAKEYYPDVELLIATVSGKIIRLSTEQVPTLGRATIGVRLIRLGEGDH--VTSVASLEK-GL----------------------------------
------------
>tr|A0A011MR77|A0A011MR77_9PROT DNA gyrase subunit A OS=Candidatus Accumulibacter sp. SK-12 GN=gyrA PE=4 SV=1
----------ILCFTNRGRVYWLKVYEVPQGTRTSRGKPIVNLFPGEKISAILPVKETDFIFMCTAQGTVKKTPLSDFSNPRRSGI-----IAVALDADD
FLIGA---EITNGRQDVVLVSDSGKAVWFDE-DVRPMTARGVRGMKLGEQQQVLSLLVADNEQTVLVATENGYGKRTALADFRHSGRGTQGVIAIAARNG
RV-VAARLVRDDDEIMLITTGGVLIRTRVREIRELGRATQGVTLIALDAGEK--LAGLEKVVESED----------------------------------
------------
>tr|H5VBK4|H5VBK4_HELBI DNA gyrase subunit A OS=Helicobacter bizzozeronii CCUG 35545 GN=HBZS_110680 PE=4 SV=1
----------FLFVTNMGQLYWLKVYRIPEMGRSAIGKALVNLIDGERIKATLSTADSPSLVFFTKKGLIKRTNLSAFGRTR-GGV-----RAIVLDEDD
ALVTAQ--ILNSGTQELFMASSKGMCIRFGIEGVREIVARGVIGMRLREG-DEIGGGVISGEEKLLSVSSKGLGKQTLAGAYRSQGRGGMGVIGMKIKTG
DL-IGIVSVDESQDLMLLTKSGKMIRMPMESIRETGRNASGVKLVSVEGDV---VVYANTCPKEES----------------------------------
------------
>tr|A0A099VUV4|A0A099VUV4_9HELI DNA gyrase subunit A (Fragment) OS=Helicobacter sp. MIT 05-5294 GN=LS69_06315 PE=4 SV=1
----------IMFITNKGQLYWLKVYRIPEASRTAIGKAVVNLINDEKIMATITTKDNESIAFFTKNGIIKRTNLSEFKNIRSVGV-----KAINLDEDD
ELVTAK--IISPSIKEILVVTYEGMCVRFGVDNVREIVARGVTAIKFKMPKDYIGATAIMDEEEILSVSEKGIGKRTEVNEYRITNRGGKGVIAMKLKTG
KL-VGIVNVDENMDLMVLTSSGKMIRVDMQSIRKAGRATSGVIIVNVDDDK---VVSIARCPKEEK----------------------------------
------------
>tr|A0A0B3B272|A0A0B3B272_9ARCH DNA gyrase subunit A OS=archaeon GW2011_AR19 GN=gyrA PE=4 SV=1
----------TRSNTTRGRVLWLKAYDIPASEKYSKGRAITNLMEDEKITNVISVKNDDSLFMATKKGVVKRISLKHFSKPRASGI-----KAINFPPGD
ILIGV---EVVKPKQEVLLATKKGKAIRFNAEDVREMASYGVTGIKLNGNDEVVSLEILD-TKAILTITKKGYGKRSLVEDYRKTSRAGKGVINLKIKTG
EI-VTTASVNDKDSIIITTAKGIVIRTSLENIRVMGRATQGVRIVKLQQGDY--VTDLVKFIEIGE----------------------------------
------------
>tr|A0A0F3R864|A0A0F3R864_RICAM DNA gyrase C-terminal domain, beta-propeller family protein OS=Candidatus Rickettsia amblyommii str. Darkwater GN=RAMDARK_1787 
----------MLFFSNIGQVYSLKLYKLPLSNPQGKGRPMVNILPNEHIANIMPLPERDNIMFATAKGNIRRSDLLDFKKLQSNGK-----IAIRLDEDD
KLIDV---KLCKEDEHILLATKAGKALRFPVESLRVKTSDGVRGMKLAKEDSVISMTVLKGIEFILTVTENGFGKRSSAYGYRITDRGGSGIINMDIKTG
LV-VGVMPVKMDDELMLITNSGKLIRCKLESVRITGRNTSGVILFKLDDGEK--VVSVSLIAETSE----------------------------------
------------
>tr|T0LJ50|T0LJ50_9EURY Uncharacterized protein (Fragment) OS=Thermoplasmatales archaeon E-plasma GN=AMDU2_EPLC00017G0001 PE=4 SV=1
----------ILYFTDLGRVFAGKVYEIEKRARTSNGISVQSFLKKETVRQIM-IPSTEHIFIATRAGYIKKIDSDQLQNIRSTGI-----RIVTLEEGD
TVVAI---EVIHEGERIAVVSEDAKIATFDPIHVRSMQARGVRSMRLPRGRSVLTAFAVSDADYIMSVSEKGIGKRTRSSEFPVHNRGTSGVFIFRERTG
KL-VSAISVKEDDEVLILTRGEKSIRIAVKDIREISRVTSGVKLVNLDDDDI--VVSVTRI---------------------------------------
------------
>tr|K1XQW6|K1XQW6_9BACT DNA gyrase subunit A (Fragment) OS=uncultured bacterium (gcode 4) GN=ACD_83C00230G0001 PE=4 SV=1
----------ILFFTDLGKIFKSKIYEIPAVSRQSKGVALQNIVSDEHVTAILTVNKDEYIMMGTESGAVKKTSLKSFKNVRTTGI-----AAITLKTGD
KLKWA---KLTSSDDIIIEVSKSGQCIVFSEKDIRPMSASGVRGMRLRQNDKVITLTMVPKDYELIVVLENGFGKRSKLSLFDIQKRGGIGIKAANVKTG
SV-VDARIVHDAFNALLVSKLGIVIRMGLSDIKLLGRVTQGVTLMRLGKGDK--VASVAIVPK-EE----------------------------------
------------
>tr|A0A0G0UTV2|A0A0G0UTV2_9BACT Gyrase subunit A protein (Fragment) OS=Microgenomates (Woesebacteria) bacterium GW2011_GWD1_41_12 GN=UU39_C0003G0001 PE=4 SV=1
----------ILFFTNKGRVFGIKAWEIPESARQAKGQALVNLLNGEEIRSILPTMKLGNLVMATKTGIIKKTQISQFENLRASGL-----IAIKLKDDD
QLVSV---HPTTGDDHIILLTRDAKSIRFPEANARPMATTGVTGIKLEKGDELIGMEVFPSKRDILTFAEKGLGKRTQIHHFPVQKRAGKGVKAAVVKTG
FL-KTAIMVTQVIDVVITSKMGQVIKLPLKNIPQLGRATQGVILMRFANKGD--SVAAAAVLEKGG----------------------------------
------------
>tr|K2DFQ8|K2DFQ8_9BACT Uncharacterized protein (Fragment) OS=uncultured bacterium (gcode 4) GN=ACD_38C00046G0001 PE=4 SV=1
----------LLFFTDKGRVFQIKVWEIPETSRVAKGQAIVNLINGEKMTAILTHRSDKFLFMCTKQGNVKKTPIEEYANIRKNGL-----ISIKLDSGD
ELGWV---VPTSGNDDTVIVSYRGQSIRFKEALVRPTDTSGVRGITLEKDDEVVSMNLVDDPLHVLVVMENGLGKKTPISAWKTQGRGGSGIKAAQVKTG
KI-VTAQLINPSHELVLTSNKGQLIKLNIKDIPTLQRQTQGVILMRVRPGEK--VAAATVVGKKDK----------------------------------
------------
>tr|A0A0G0KDX9|A0A0G0KDX9_9BACT Gyrase subunit A protein (Fragment) OS=Microgenomates (Daviesbacteria) bacterium GW2011_GWF2_38_6 GN=US99_C0050G0001 PE=4 SV=1
----------ILFFTDKGRVFQIKVWEIPETQRAAKGQAIVNLINGEKVTANLTTRQESYFFMCTQKGTVKKTSLEEYANIRKNGL-----VAIKLDPKD
ELGWV---CPTSGKDDLIIVSRQGKSIRFSETQVKPTDTSGVRGIRLSKDDEVVSINIVENEDALLVIMENGLGKKTLFSSWSKQGRGGQGVKAAQVKTG
RI-VTTQVVNKNTDLVLTSTKGQLIKMDLKQVPTLQRQTQGVILMRVRVGEK--VVAATVVASKER----------------------------------
------------
>tr|W0FLN6|W0FLN6_9BACT DNA gyrase subunit A (Fragment) OS=uncultured bacterium Contigcl_1149 PE=4 SV=1
----------IMFFTNTGRVYSLKCYQIPEAGRQARGTAIINLLQGEKVSTMLPMPKEQNLVMATRNGMIKKTALEEFRNLRKNGL-----IAIALREGD
ELIGV---RLSNGDDEMLVSTRKGKCIRFNERHVRNVNSIGVRSMRIAEGDEVIDIAAVEP-TTVLAITTLGYGKRTEPDEYREQGRGGMGIKAMQLKTG
DL-AALMFVHEDEDILLITDDGTIIRARAADVRLCGRSTQGVRIMRLAEGST--VVGVCRAEKEEE----------------------------------
------------
>tr|A0A0E8TRB4|A0A0E8TRB4_STREE DNA gyrase subunit A OS=Streptococcus pneumoniae GN=gyrA_3 PE=4 SV=1
----------ILFFTNKGKVYRTKGYEIPEYSRTAKGIPIINLLGGEWINAIIPIREGDFLFFTTKQGISKRTPLSSFANIRTNGL-----IAISLREED
EVISV---RLTSGDKDIIVGTSNGMLIRFNEQDVRSMNAAGVKAITLGDEDQVVGMEIVEE-VNVLIVTKNGYGKRTPIDEYRLQSRGGKGLKTCNIKNG
KL-VAVKSVTGEEDIMLITAAGVIIRMPVDQISQMGRNTQGVRLIRLEEDQE--VATVAKAQKDEE----------------------------------
------------
>tr|R7M5F1|R7M5F1_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:914 GN=BN809_00967 PE=4 SV=1
----------VLFFTNKAKVYRLKGYEIPEFSRQSKGLPIINLLSGEYVTALVNGNIDNYFVFATKMGLVKRTEISEFYNIRNNGK-----KFITLRDDD
DLISV---KKTDGTYDILMASSNGRLVRFPENLVRVMGASGVRGINLDDG-ILVGMEVANS-IDVLVVTEKGYGKKTPISEYRITNRGGKGVKTLNIKNG
TI-TSFKAVDKDKDLIIITNEGIIIRIDINSISMMSRVTQGVRLINLRENQV--VSSISVVDKEIE----------------------------------
------------
>tr|A0A081D494|A0A081D494_9MOLU DNA gyrase alpha subunit (Fragment) OS='Chrysanthemum coronarium' phytoplasma GN=gyrA PE=4 SV=1
----------HLFFTNKGKVYQLKGYEIPLGQRQSKGSHLVNFLPDEFLTSFTSVKNQSYLFFATKKGIVKKTPLKEYSHISKRGL-----IAIRLKEND
EVLTV---NKTTGTKNIILASNNGNAICFCETKIKSINSMGVIGMRLGSDEFLVGAALFDTDQNILVMTENGFGKITNVNQYRIQERSGKGSKTIKVQKG
RL-ITLQVVLPTDDLIVSSDKGQVVRVAIDQITKTNKATQGTRIIKLKTGHK--AVSVAVVKKEVL----------------------------------
------------
>tr|A0A0J7LDP4|A0A0J7LDP4_STAAU DNA gyrase subunit A (Fragment) OS=Staphylococcus aureus subsp. aureus GN=OO23_11455 PE=4 SV=1
----------VLFFTNKGRVYKLKGYEVPELSRQSKGIPVVNAIEDEVISTMIAVKDSEFLVFATKRGVVKRSALSNFSRINRNGK-----IAISFREDD
ELIAV---RLTSGQEDILIGTSHASLIRFPESTLRPLTATGVKGITLREGDEVVGLDVAHA-DEVLVVTENGYGKRTPVNDYRLSNRGGKGIKTATIRNG
NV-VCITTVTGEEDLMIVTNAGVIIRLDVADISQNGRAAQGVRLIRLGDDQF--VSTVAKVKEDAD----------------------------------
------------
>tr|T0N9W3|T0N9W3_9CLOT Uncharacterized protein OS=Clostridium sp. BL8 GN=M918_23960 PE=4 SV=1
----------ILFFTNRGKAYKLKAYEIPEGSRTSKGTNIVNILPGESIQAVISLRTDKYLVMGTKEGIVKKTSLDKYEHIRKNGL-----NAINLREND
ELIGV---RITTGNSEIVFVTKCGYSIRFSEKDVREMTATGVKAITLREDDIAVSMIIAKPNEELLVISEKGFGKRTDISEYTLQRRGGKGLKTYRVKTG
RL-VGARVVRDLDEMMLINSDGIIIRINVSDISTTSRNAMGVTLMKTGEDVN--IVAIAKINYVDA----------------------------------
------------
>tr|H5TUE3|H5TUE3_9ACTN DNA gyrase subunit A (Fragment) OS=Gordonia otitidis NBRC 100426 GN=gyrA PE=4 SV=1
----------ILFFTTKGRVYRAKAYELPEANRTARGQHVANLLAEERIAQVIQLKTQDYLVLATRNGLVKKSKLEDFDSNRSGGI-----AAINLRGED
ELVGA---QLCSSDDDLLLVSQKGQSIRFHADTLRPMQTSGVQGMRFNGDDELLSLNVVREGTYLLVATSGGYAKRTPMDDYPVQGRGGKGVLTIQHRRG
EL-IGAIIVDDDSELYAITSGGGVIRTAAKQVRKAGRQTKGVRLMNLDEGTT--VIAIARNADEPE----------------------------------
------------
>tr|A0A0E9GCY0|A0A0E9GCY0_CHLTH DNA gyrase subunit A OS=Chlamydia trachomatis GN=gyrA_5 PE=4 SV=1
----------LLFFTNLGRVYRAKAYEIPEGGRDAKGQHVANLLAEEHIAQVLAIRDEVYLVLATKSGLVKKTPLKLYESSRTGGI-----IGINLREDD
ELVSA---QVINADQDLILVSRDGQAVRFVATQLRPMSTAGVRGMRFRGDDELLSMEVPREGTDLLIVTDSGYAKRTPVEEYPTKSRGTMGVRVGKLERG
GL-VGALVVNPDEDVMVITESGKLVQVNASDVRPTARNTMGVIFARPDEDDR--IIAITPNPERDI----------------------------------
------------
>tr|V7KHH6|V7KHH6_MYCPC DNA gyrase subunit A OS=Mycobacterium avium subsp. paratuberculosis 10-5864 GN=O978_00060 PE=4 SV=1
----------ILFFTTQGRVYRAKAYELPEASRTARGQHVANLLAEERIAQVIQIRSEDYLVLATRNGLVKKTKLTDFDSNRSGGI-----VAINLRDND
ELVGA---VLCSAEDDLLLVSANGQSIRFSATALRPMATSGVQGMRFNADDYLLSLNVVREGTYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYRRG
RL-VGALIVDEDSELYAITSGGGVIRTAAGQVRKAGRQTKGVRLMNLGEGDT--LLAIARNAEEAA----------------------------------
------------
>tr|R7BW94|R7BW94_9FIRM DNA gyrase subunit A OS=Firmicutes bacterium CAG:270 GN=BN579_01083 PE=4 SV=1
----------IMFFTNTGRVYRLKAYEIPESGRTARGSAIVNLLQGEKITAVIPLADEEYLLMATKYGVVKKSSIMEYANIRKTGL-----AAITLKDDD
QLIEV---KYTEDDEDVFLVTKNGQCIRFHESDVRCITSMGVRGINLTGDDEVIGMQLDSQGEALLIVSANGMGKRTLTSEFTAQHRGGKGIKCYKIKTG
DV-VGVKAVNDDNEIMMITTGGIIIRTAVASISMLGRNTSGVKVMNVGENVE--VASIAKVREEKL----------------------------------
------------
>tr|D4KES2|D4KES2_9FIRM Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit OS=Megamonas hypermegale ART12/1 GN=MHY_22200 PE=4 SV=
----------ILFFTNKGLVYQLKGYEIPESGRTAKGTAIVNLLPEETITAIIPIKESKYLFMATRHGIVKKTGLSEFDTNKKTGL-----IALSLKEND
ELIGV---KLTDGNRQIIIGTRDGMSICFNEQDVRPMTARGVIGIKLKGEDTVIGMDNIRD-CEVLTVTEHGFGKRTATSEYRTQTRGGIGLINIKVKTG
FV-IGIKVVDSQQEFMLISTEGIVIRSNIEEVSVIGRNTQGVKMMNMDNNDK--VAALAAFEIKED----------------------------------
------------
>tr|T2RDJ6|T2RDJ6_CLOSO DNA gyrase C-terminal domain, beta-propeller family protein OS=[Clostridium] sordellii ATCC 9714 GN=H477_5186 PE=4 SV=1
----------LLFFTNKGRVYRLNAYEIPEAKRQAKGSAIVNLLQDEKIATMISIDDSDYLLLATKNGIVKKTKREEFKNINKSGL-----IAIGLREDD
ELIDV---RVTDGSEDVILVTKGGMSIRFDENDIRHMTAMGVKGITLNKNDKVVSMNLCSEGTDLLVVSENGFGKRTSIEEYRSQIRAGKGIKTYNIKTG
DI-VGAQMVNEDDEMMIINSDGVLIRLRVNEISLFGRVTSGVKLMKTNDEVN--IVSIAKIEMEE-----------------------------------
------------
>tr|A0A0F3GNT3|A0A0F3GNT3_9BACT DNA gyrase subunit A OS=Candidatus Magnetobacterium bavaricum GN=MBAV_005485 PE=4 SV=1
----------ILFFSNFGRLYLLKIYQIPEAGRAAKGKAIVNLLQGETIATALPIKGFDYLIMFTKKGIVKKTLLREFSNPRGKGV-----IAINIDEDD
ELMAV---RYADGQSDVLIGTCLGHAIRFNEEDVRSTSSRGVKGIRLKKDDEVVSAEVVED-TTLLNVTEFGFGKRSNLQDYPLQARGGQGVKSIKVKGG
KV-VGLIQVRDEDEIMVVTKSGKSIRTIAGAISVTGRNTQGVKLMDVGKDNM--IMSIGKAAEKDR----------------------------------
------------
>tr|T1A347|T1A347_9ZZZZ DNA gyrase subunit A (Fragment) OS=mine drainage metagenome GN=B2A_06923 PE=4 SV=1
----------VLFFTNLGRVYRLKAYELPEGSRQSKGKAVVNLLAGERVQTLLPIHDAGSLFFATRRGLVKRTALGQFQNIRTSGI-----QAILLEEGD
ELVDVA--QVADEASEILLATASGQLVRFALGEVRPMATYGVIGVRLSEETDDVAMAPVS--PTLLSLTSTGYGKQTPVAEYRKTARGAKGVRTIKTRNG
SV-VAVLPATDASELLVTTRTGVTIRMTVKGIRTQSRNTLGVRVIRLDEGDE--VRDAIVLPAPEE----------------------------------
------------
>tr|T0YX31|T0YX31_9ZZZZ DNA gyrase, A subunit (Fragment) OS=mine drainage metagenome GN=B1B_15047 PE=4 SV=1
----------VLFFTNQGRVYRLKAYELPEMGRHAKGKAIVNLLPGERIQTELPVRGSGTLVFATARGLVKRTELSRYQNIRVTGI-----QAILLEEGD
ELVDVA--L-TDGGSEVLLATREGQVVRFAERRVRTTATYGVRGLKLKG-REDVAMTPVS--PSLLTVTSTGFGKRSPVEDYRLTGRGASGVIGIKTRNG
HV-VTVLPVTGDDEVLLTTQKGITLRAPVGQVREQSRNTLGVILIRVEPGDE--VMAAVRLVAPGE----------------------------------
------------
>tr|A0A023CYV5|A0A023CYV5_9LACO DNA gyrase subunit A OS=Lactobacillus sucicola DSM 21376 = JCM 15457 GN=JCM15457_1961 PE=4 SV=1
----------ILFFTNMGKVYRMKGYEIPEYGRTAKGIPVINLLGGEKIQAVINVSKGQYLFFTTRQGIVKRTAVEEFSNIRSNGL-----KAITLKEGD
ELIGV---QITNDERNIIIGTHLGYAVSFAEKAVRSMSAAGVRGIRLREDDYVVGADILYP-SRVFVISEKGFGKQTAAADYPIKGRGGKGIKTANIKNG
PL-AGLTTVLGGEDIMLITDKGVMIRFGIESVSQTGRATLGVHLIKVDADAV--VSTMAKVEPEQ-----------------------------------
------------
>tr|W4L713|W4L713_9DELT Uncharacterized protein (Fragment) OS=Candidatus Entotheonella sp. TSY2 GN=ETSY2_50685 PE=4 SV=1
----------LLFFTNIGKVHWLKVYRIPQAGRVARGKAAVNFLQDEKISTVVPIRREVYLIMATKKGIVKKTELTAYGNPRQTGI-----IALTLDEGD
ELIGV---GVTSSDQEIFLGTKNGLSIRFSEDDVRSITGRGVIGIRLDDDDEVVGMAVLSPEASILTVSEGGYGKRTHESEYRTQSRGGRGLINLRVKTG
RV-IGVRQVFESDDVMLMSDQGNLVRIEVSEVNEIGRNTQGVRLISLNEDQR--LVGVVRIEDDNG----------------------------------
------------
>tr|A0A0E9F116|A0A0E9F116_CHLTH DNA gyrase subunit A OS=Chlamydia trachomatis GN=gyrA_9 PE=4 SV=1
----------ILFFTTRGRVYRLKAYEIPESSRQSKGTQIRNLLNDESVESIIHVKDDSNIVMATKSGIVKRTSFEEFQNIRKSGL-----IAITLKDGD
SIVST---RITTGEEDIMLVTKDGMSIRFKETDIRKMTAMGVKGISLNDDDEVVSMEIASDDKLMLVISEKGYGKLTPMSEYKVQNRAGKGIITYKVKTG
KL-VSAKIMESNDDIMMITSNGIIIRIQIDGISVMGRSTSGVKLMNITDSDV--V-AVAKYIGD------------------------------------
------------
>tr|U5NBX2|U5NBX2_9MOLU Uncharacterized protein OS=Mycoplasma parvum str. Indiana GN=PRV_00175 PE=4 SV=1
----------LLIFTAFGRVYRINSNKVQVLR--SKKVELQDVEPIDKVVRIISADQQNFAFLGTKEGMVKKMFLGEFQSVRRSGA-----KIISLRGDD
DLLDV---KIIGKDDEIFLTSTSGHLVRFKSSEVREMEAIGVEGINLSNKKDLNFQVISISCEEIFTLTRKGKSKYTKLDEYKLTGRGRKGMYAYKFKNG
TC-FAISVFNTSEFLFLITSSGKVVRLRADAISSRNRASAGVGIIRLDKKKQEEVVHCFKYMEFKK----------------------------------
------------
>tr|X0ZXG7|X0ZXG7_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=S01H4_03114 PE=4 SV=1
----------ILFFTSKGVVYRRRAYQIPEGGRTSRGVAIVNLLGDEHITTIIPIES-SCLFMATKKGKIKKVPLSHFYNLRNVAI-----IAIRLLPED
ELIGV---RLAGEEERIILTTKRGNSTCFSGNQIRPLVACGLRGISINENDHLLNISLVSP-EDLLIVTEGGLAKRTPLKKFREKKRGGKGARSIKLEKG
LV-VAVKVVSEEDELVLISQNGIVIRVPVKEIRHTGRYSQGVRVMNLAPEDK--VASVALVSSENV----------------------------------
------------
>tr|V4VZH4|V4VZH4_9ROSI Uncharacterized protein (Fragment) OS=Citrus clementina GN=CICLE_v10017460mg PE=4 SV=1
---------------DRGIVYSARAYKIPECTRNAAGTPLVQILSGERITSIIPVSEAGFLVMLTMNGYIKKVSLNLFSSIRTTGI-----IAIQLVPGD
ELKWV---RCCTNDDLVAMASQNGMVILSSCDIIRSLNTRGSVAMRLKDGDKMASMDIIPAAPWLLFVSESGHGKRVPLSSFRKLPLNRVGLIGYKFEDG
NP-MSLIAKDGESDVVLVSQSGTVNRIKVRDISIQARYARGVILMRLELSGKIQSASLISVTEPET----------------------------------
------------
>tr|U1PZI3|U1PZI3_9EURY Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit (Fragment) OS=Haloquadratum sp. J07HQX50 GN=J07HQX50_0
----------LLYFTTHGKVYQLKTYQIPEMSRTARGKSAVNILEDEQITAVVNTADEQYLTMATKNGYVKRTKVGEFQNIHQTGI-----IAVNLSADD
KLVDV---EVTSGKRDLLLATRSGMAIRFSESEVRPMTARGVRGIKLENNDTVAALAAVRETEWVLTVTENGYGKRTDVQQYRRQSRNGKGLIDIKTRNG
KV-CELETVGTHDNVFVMSEQGQILRTAVDEISTVSRNTMGVIIMRLDNSDA--VSSVDVQEMTSE----------------------------------
------------
>tr|A0A0E9E8W5|A0A0E9E8W5_CHLTH DNA gyrase subunit A OS=Chlamydia trachomatis GN=gyrA_3 PE=4 SV=1
----------LLIFTNFGQCYWLKVWQLPEGERRAKGKPIINFLEGEQVAAVLNVKREQYLFLATKKGVVKKVSLDAFGSPRKKGI-----RALEIDDGD
ELIAAR--HIANDEEKVMLFTRLGMAVRFPHDKVRPMAARGVRGVSLKNEQDFVSCQVVTEDQSVLVVCDNGFGKRSLVCDFRETNRGSVGVRSIVIRNG
DV-LGAISVTDCDSILLMSAQGQAIRINMQDVRVMGRATQGVRLVNLREGDT--LVAMEKLSINTE----------------------------------
------------
>tr|A4ECR3|A4ECR3_9ACTN DNA gyrase C-terminal domain, beta-propeller OS=Collinsella aerofaciens ATCC 25986 GN=COLAER_02249 PE=4 SV=1
----------VLFFSSKGKVYRLKVHELPVGTRQARGTAIVNLLPGEKIASVISCREPAYLMFATKSGMVKKTVMSAYDRSRRDGL-----IAINLRDDD
ALLNV---RRVREGDKIILATTAGKAIMFSEEQVRATDTSGVRGIGMKDGVSVLGMEVTNGNGDLFVITERGYGKRTPVADYPEQNRGGQGVYTIQMRKG
NL-AAMKTVGPQHELFIVTEGATVIRVKTDEISQTGRATQGVKMMTVDDNDR--ICAVARMTAAKE----------------------------------
------------
>tr|F4N7W8|F4N7W8_YEREN Putative uncharacterized protein OS=Yersinia enterocolitica W22703 GN=YEW_JA39640 PE=4 SV=1
----------ILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPNERITAILPVREEEHIFMATASGTVKKTALTEFSRPRSAGI-----IAVNLNEGD
ELIGV---DLTDGTNEVMLFSALGKVVRFPESQVRSMTATGVRGINLNGDDRVISLIIPRGDGEILTVTENGYGKRTAVEEYPTKSRATQGVISIKVRNG
KV-VGAVQVAPTDQIMMITDAGTLVRTRVSEVSVVGRNTQGVTLIRTTEDEH--VVGLQRVAEPEE----------------------------------
------------
>tr|W1JKF4|W1JKF4_9BRAD DNA gyrase subunit A (Fragment) OS=Bradyrhizobium sp. CCGE-LA001 GN=BCCGELA001_36507 PE=4 SV=1
----------VLFFSSRGQVYKEKVWRLPMAAPNARGKALINILPGERITTIMPLPEWGDVMFATTGGNVRRNKLSDFVDVRRSGI-----IAMKLDDGE
SIVDV---QICTERDDVLLTAAGGQCIRFPVPDVRVTTSMGVRGIALGEGDKVISLAILRHVQVVLTVSVNGYGKRTSSYEYRTTGRGGKGIVAMSVRNG
NL-VASFPVEDADQIMLVTDKGQLIRCPVEGIRIAGRSTQGVIVFDTAEDEH--VVSVEHITDEAE----------------------------------
------------
>tr|A0A0P9AA29|A0A0P9AA29_9GAMM DNA gyrase subunit A (Fragment) OS=Psychromonas sp. PRT-SC03 GN=JI57_01055 PE=4 SV=1
----------ILCFSTRGRLYWLKVFQLPHASRQARGRPIINILPGERITAILPVRKDDFVFMATANGTVKKTALSAYSRPRASGL-----IAINLNDDN
ELIGA---LITDGSNDIMIFSDAGKVVRFKEAGVRPMTATGVRGIKLKEGERAVSLIVPNATGHILTCTENGYGKRTPLSDYASKSRATQGVISIKVRNG
KV-VGAVQVDENDEIMLISNRGTLVRTPVHGVSIVGRNTQGVTLIKTRDDEK--IVALQRIEEVQE----------------------------------
------------
>tr|A0A0Q1C5K8|A0A0Q1C5K8_NEIME DNA gyrase subunit A (Fragment) OS=Neisseria meningitidis GN=LD10_11755 PE=4 SV=1
----------LMCFTNLGKCHWIKVYKLPEGGRNSRGRPINNVIQGEKVSAILAVREPEYVFFATAQGMVKKVQLSAFKNVRAQGI-----KAIALKEGD
YLVGA---AQTGGADDIMLFSNLGKAIRFNEYGVRPSGSGGLRGMRLPADGKIVSLITFAPELQVLTATANGYGKRTPIADYSRKNKGGQGNIAINTRNG
DL-VAATLVGETDDLMLITSGGVLIRTKVEQIRETGRAAAGVKLINLDEGET--LVSLERVAEDES----------------------------------
------------
>tr|R7KSY3|R7KSY3_9BURK DNA gyrase subunit A OS=Sutterella sp. CAG:521 GN=BN692_00644 PE=4 SV=1
----------ILCFSDFGRMYCLDVYALPEGSRTSKGRPIINSVPGERITVVLPIEDDDYVFMATANGVVKKTRLKDFANVRRSGI-----NAAGLDDGD
HLIGV---AITDGEHDVMLFSDAGKAVRFSE-DVRPMGARGVKGMALEDGQKVIAMIVADSEQTVLTATENGFGKRTLVSEYTRHGRGTKGMIAIQTRNG
KV-VAATLVNDADEVMLLTQKGKIVRTPVSDISVLKRATQGVTLIGLKDDSL--VA-VQRIAEEDV----------------------------------
------------
>tr|W7Q5M1|W7Q5M1_9GAMM Uncharacterized protein OS=Halomonas sp. BC04 GN=Q427_24745 PE=4 SV=1
----------VLLFSNKGKVYWLKVYEMPNASRGSRGKPLVNMLPGEAINAILPVRDRAYIFFATAKGTVKRTSLDQFSRPRSVGL-----IAIDLEEGD
RLVGA---AITSGSDHAMLLSSNGKAIRFEEGNVRSMTARGVRGMRLQGGAEVISLIIPQSQIYILTASENGYGKRTRLEEFPLRGRGGQGVIAMQTRNG
SL-VAAMQVYSADEMMLITDKGTLVRTRVDEVSITSRNTQGVMLIRLGENEK--LVKTVRIDEPEE----------------------------------
------------
>tr|A0A009J8M0|A0A009J8M0_ACIBA DNA gyrase C-terminal domain, beta-propeller family protein OS=Acinetobacter baumannii 1396970 GN=J514_1424 PE=4 SV=1
----------VLCFTNVGKVYRLKVFEVPQASRGAKGRPIVNLLPTETVTAILPLTEPEYVFMATASGTVKRVELEQFANIRSNGL-----RAIELNEED
TLIGV---AITDGNQQIMLFSNEGKAIRFAETDVRAMTAKGVRGMRVSFASSTLSEEDAEVEGEVLCASANGYGKRTPVNDFPTKKRGGKGVIAIKTRNG
EL-VGAVSIDETKELLLISDGGTLVRTRAAEVAMTGRNAQGVRLIRLSEEET--LVGVVSIEAVED----------------------------------
------------
>tr|A0A0A3WAW6|A0A0A3WAW6_VIBPH DNA gyrase subunit A (Fragment) OS=Vibrio parahaemolyticus GN=HC02_13375 PE=4 SV=1
----------ILCFSTRGKTYRLKVYQLPLASRTARGKPIVNILPGERITAILPVDESAFIFMATGDGTVKKTSLDQFANVRSNGL-----IAVNLRDDD
SLIGV---DITTGSSDIMLFSKAGKVVRFSEDKVRAMTAAGVRGMKLADDDQVVSLIVPSNEGDILTVTQNGYGKRTELAEYPTKGRATQGVVSIKVRNG
PV-VGAVQVEEGDEMMMITDAGTLVRTRVAEVSQVGRNTQGVTLIRTAEDES--VVGLQRIDEVEE----------------------------------
------------
>tr|W4RPE9|W4RPE9_9BACI DNA gyrase subunit A OS=Bacillus boroniphilus JCM 21738 GN=JCM21738_3203 PE=4 SV=1
----------ILFFTNKGKVYRSKGYEIPEFSRTAKGIPIINLLEGEWVNAIIPVEEVDFLFFTTKEGISKRSPLSSFANIRNNGL-----IALNLREGD
ELISV---RMTDGSKEMIIGTKNGLLIRFPETDVRSMTATGVKGISLSGDDEVVGMEVLEE-AEILVVTKNGYGKRTPSEEYRRQGRGGKGIKTCNIKNG
DL-VTMKVVTGEEDLMLITTGGVLIRIPVSSISMTGRNTQGVKLINLNKAENEYVATVAKVDKEEE----------------------------------
------------
>tr|A0A0P7FF36|A0A0P7FF36_9XANT DNA gyrase subunit A (Fragment) OS=Xanthomonas arboricola GN=AN651_16040 PE=4 SV=1
----------LLTFTSSGKVFWLPVYQLPEAGSNARGRPIINWIPGERVQAVLPVREADYVFFATRNGTVKKTPLSEFAFRLARGK-----IAINLDEGD
ALVGV---ALTDGDRDVLLFASNGKTVRFGESTVRSMTATGVRGIRLTKGEEVVSLIVAERAAYILTATENGYGKRTPLTEYPRKGRGTQGVIGIQTRNG
KL-VRAVLLGATDEVLLISDGGTLVRTRGSEISRVGRNTQGVTLIRLSKGEK--LQAVERLDASLD----------------------------------
------------
>tr|K8A7N3|K8A7N3_9ENTR DNA gyrase subunit A OS=Cronobacter muytjensii 530 GN=BN135_1144 PE=4 SV=1
----------ILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPNERITAILPVREEENVFMATASGTVKKTALTEFSRPRTAGI-----IAVNLNEGD
ELIGV---DLTAGKDEVMLFSAQGKVVRFKEDAVRPMTATGVRGIRLGEGDSVVSLIVPRGEGAILTATQNGYGKRTAVEEYPTKSRATKGVISIKVRNG
PV-VGAVQVDDADQIMMITDAGTLVRTRVSEISVVGRNTQGVILIRTAEDEN--VVGLQRVAEPVD----------------------------------
------------
>tr|D7H896|D7H896_VIBCL DNA gyrase, subunit A OS=Vibrio cholerae RC385 GN=VCRC385_01969 PE=4 SV=1
----------ILLFSTRGKTYRMKVYQLPLASRTARGKPIVNLLPNERITAILPVTESEFIFMATGDGTVKKTSLDQFANVRANGL-----IALNLRDED
SLIGV---DITDGESEIMLFSKFGKVVRFKESGVRPMTAAGVRGMKLADGDQVVSLIVPKTEGDVLTVTENGYGKRTSLSEYPTKGRGTQGVVSIKVRNG
SV-VGAVQVAEGDEFMMITNAGTLVRTRVAEVSQVGRNTQGVTLIRTSEGES--VVGLQRIDEIEE----------------------------------
------------
>tr|G8C2J6|G8C2J6_9MOLU DNA gyrase subunit A OS=Candidatus Mycoplasma haemominutum 'Birmingham 1' GN=MHM_00260 PE=4 SV=1
----------ILLFTNIGKVYKLSLDDEKAIVVGTWPEELVNISSNERVVQLLPIKNEEFFFMSTEKGMVKKLEISELSSITRAGK-----RVITLFEGD
SLSHV---IKIGAEDEVLLGLSTGYAVRFSSTSVRASASTGVKSIEIEPKSGAIISL-SSTSALVVSIDEEGKGKCTSLREFRLTSRRSKGTIAYKLSSN
SL-VTCAIVHDNEELVLLSDKNRINRIGVDQVTLRGRNTAGTILVRLEQSG-EKLFQFAKHAPSEV----------------------------------
------------
>tr|V9R9J1|V9R9J1_9MOLU Uncharacterized protein OS=Mycoplasma ovis str. Michigan GN=OVS_03780 PE=4 SV=1
----------ILIFTNLGRVYMMNGNDFTKNYSS--LQSNYCSSNKERIVSVLSDHDSDQLFLITEKGKCKKLETKHLRNVSKSGK-----IIIQLKDGD
QLKQV---QKIDSQSEIVLISSEGKAVRFSSSDVRSMNSMGVKGINLGSRELEEGKLSFLTTNRLLIIGDKGYGKIFKLPQISLVKRGNKKGMTCHNTSG
WI-IFASCVNWDDHLIGLTYRNNLHKLQVDKLPVLNRYSRGAHILGEKQRFYDSLVEVIKYTN-------------------------------------
------------
>tr|L7VMV9|L7VMV9_9FLAO DNA topoisomerase (ATP-hydrolyzing) OS=Candidatus Uzinura diaspidicola str. ASNER GN=gyrA PE=3 SV=1
IEDLIYDEQMVLTISNKGYIKRTPLSEYKRQLRGGIGNRGASTKNEDFLEHILVASNHQYMLLFTKKGKCYCKRVYEVPERSKKSKGRFIQNLIQILPED
KVQAYIILGNFVKKHYVVMVTENGNIKKTPLGQYSKPRIHGIKAISIREGDKLLEAKLTNGQCEIILAIKSGKAIRFSEDKVRSMGRTAIGVVGINLIKN
DKVIGMVCIEKKEDILVVSEKGYGKRSLLDDYRVTNRYCKGVKTFNITR-KTGNLIAIKNVTETNDIIIINKSGYTIRLSVSELRIMGRATQGVKLINLK
KGTIAAVET---
>tr|W5WB66|W5WB66_9PSEU DNA topoisomerase (ATP-hydrolyzing) OS=Kutzneria albida DSM 43870 GN=KALB_5036 PE=4 SV=1
-PLEVADDPCQVILSATGLVARTAAESEEVSE----GRRRSGRAKHDAVSAMVHSTARGRVLLVTNLGRAFKTEVLPLPVLPEQVGGMAASELVPLEKGE
RVIGLAPLSEDNGSPGLALGTRQGVVKVCA--PEWPVRSEEFEVIGLREGDEVVGATWLTDSESLVFVSSDASLLRYAASLVRPQGLKGGGMAGINLALA
ETVFFGAVREDTGEPMVVTSTGVGKVTPFSEYPSKGRATGGVRAQRFLKGES-RLDVAWVGP---RPAAAKANGSSVELPEVD---QRRDGSGTPSAA--
------------
>tr|A0A0K3BKA3|A0A0K3BKA3_9PSEU DNA topoisomerase (ATP-hydrolyzing) OS=Kibdelosporangium sp. MJ126-NF4 PE=4 SV=1
-PLEVADDPCQVILSATGLVARTAAESEESNE----ARRRNGRAKHDTVAAVVHSTARGQILLVTNQGRAFKTDVLPLPVLPEASGGMAAKELVPLEKGE
KVVGIAPLGEQGASPGLAVGTKYGVVKVCA--PEWPVRSDEFEVITLKDGDEIVGATWLKDTETVAFVSSDSSLLRFAASLVRPQGLKGGGMAGINLGKA
EAVFFGAVRDDDGEPMVVTSTGLSKVTPFAEYPAKGRATGGVRTHRFLKGET-RLALAWVGP---RPAGASNTGSAVELPEPD---VRRDGSGHAHPG--
------------
>tr|W7IJ06|W7IJ06_9PSEU DNA topoisomerase (ATP-hydrolyzing) OS=Actinokineospora spheciospongiae GN=UO65_3943 PE=4 SV=1
-PLEVADDPCQVILSATGLVARTAAESEESSE----ARRRNGRARHDAVSAVVHSTARGQVLLVTNHGRAFKTDVLPLPVLPEQVGGMAAGELVPLVKGE
KVVGIAPLGEQAASPGLALGTRQGVVKVCA--PEWPVRSDEFEVISLKPGDEVVGATWLGDTESLVFVSSEASLLRYAAGLVRPQGLKGGGMAGINLPAA
HALFFGAVAADPGDPVVVTSTGQSKVTPFAEYPAKGRATGGVRAHRFLKGET-GLVLAWVGS---RPAAAGKNGSAVELPAIE---PRRDGSGAAHPG--
------------
>tr|K0JZB4|K0JZB4_SACES DNA topoisomerase (ATP-hydrolyzing) OS=Saccharothrix espanaensis (strain ATCC 51144 / DSM 44229 / JCM 9112 / NBRC 15066 / NRRL 
-PLEVADDPCQVVLSATGLVARTAAESEEASE----ARRRNGRVKHDAVAATVHTTARGQVLLVTNRGRAFKTDVLPLPVLPEQSGGMAASELVGLDKGE
RVVGIAPLSD--TSPGLALGTRQGVVKVCA--PEWPVRSDEFEVITLKEGDEVVGASWLGSEETLVFVSSEASLLRYSASLVRPQGLRGGGMAGITLPGA
HAVFFGAVRDDDGEPMVVTSTGQSKVTPFAEYPAKGRATGGVRAHRFLKGET-GLALAWVGP---RPAGAADNGSPVELPEVD---ARRDGSGHAHPG--
------------
>tr|J1F984|J1F984_9HELI DNA topoisomerase (ATP-hydrolyzing) OS=Thiovulum sp. ES GN=ThvES_00011340 PE=4 SV=1
-EDLIPNLPMVVTITNTGYVKRVPVSLYEQQK----GRIALKTHEDDFVKDFFTSNSHDTLLILTNFGKIFWLKVYKIPEATRQAKGKAIVNLIQISEGE
EVRAIIPTEDFNK-KSLFFFTKNGLIKRTNLSDYGNIRSNGIKAIKLNEDDELVTARISDSTKFVSIFTDKSQAIRFEIGKTRDQGRDTRGVTGIKFKKG
DFVVDGILLNEE-EILTVSENGLG-RSSTSEFRLTNRARSGVIAMKLSDRAG-RSLIGAVVV---ELMILTESGKLIRLSFENIKTQSRNTSGVILVS--
------------
>tr|Z4XF75|Z4XF75_9ACTO DNA gyrase C-terminal domain, beta-propeller OS=Actinomyces sp. ICM54 GN=HMPREF1522_1695 PE=4 SV=1
--LQIPDDPCVVVLSSSGALARVEGGDPLE--PGP-------RAASDGWRVQLPSTARSQVAVVTEDGVAHRIDVVDLPALPRFEGAMPASLLLHTDVP-
-AVGLL--DP-EGTDVVAMGTARGTVKRLRPDV---LQRDEWEVIALEDGDRLVGFDRCSDEADLVFISSDAQLLRTPAAKVRPQGRTAGGMAGMKLNPG
AEALGFWVVEAALGALPGTGQTTVKVTPFECYPTKGRGGQGVRCQRFLRGE-DRLDIAWVG--TKPARAASADGSPVELPA---EDERRDGSGVPI----
------------
>tr|C0W364|C0W364_9ACTO DNA gyrase C-terminal domain, beta-propeller (Fragment) OS=Actinomyces urogenitalis DSM 15434 GN=HMPREF0058_0308 PE=4 SV=1
--LTVPDDPCRVLLSATGLVARVAGAEAVPR-TGE-------RQRHDALTSQVPTTARSRVGVVTDTGRLVVMEVLSTPEVPRLEGGQPVGLLVDLEPGE
TVVGLVPVGE-AQREPVVLATAGGVIKRVKPGDE-PARGESWEVISLADGDRVVFAGIAADTDVLTLVTDDAQLLRFEASKVRPQGRGAAGMAGISLHEG
ARVIAGASVELAEGALPGMDSGSVKVTPLDRYPAKGRATGGVRAQRFLRGE-DQLVVAWVG--VGPARAVGSGGQGVALPE---VDERRDASGTAL----
------------
>tr|U1Q4S2|U1Q4S2_9ACTO DNA gyrase domain, beta-propeller (Fragment) OS=Actinomyces johnsonii F0542 GN=HMPREF1979_02082 PE=4 SV=1
----------------------TPGAEPVAR-IGG-------RRPHDALTSQVATTARGRIGAVTDTGRLVLLDVVSTTEVPRTEGATPARQLVDIDPEE
KVVGLVPVGP-ADHAPIVLATAGGVIKRVKPGDE-PRNAEAWEVISLSGGDRVIFAGTAADTDFLALVTSDAQLLRFQAAKVRPQGRGAGGMAGISLREG
ARVIAGAAVELSEGSLPGTGGGSVKVTPLDRYPAKGRATGGVRSHRFLRGE-DELVTAWVG--VAPARALSEDGKPIALPQ---ADERRDGSGSPL----
------------
>tr|R5MUM4|R5MUM4_9BIFI DNA topoisomerase IV subunit A OS=Bifidobacterium longum CAG:69 GN=BN755_01232 PE=4 SV=1
---------------------------MDVFTSDE-------RLRDDQITTIFETSTRATYGLVTSAGRLVLAHVVDLPALPATAGGVQADELIGMIRGE
RVITAIAMEQPKPLPSLAIGTRNGVIKRWNREAP--TTMDSWPVIDLKDGDEVVFAAVAEDDDRLVFISSDSSLLTFEAKNVRPQGRTAGGMAGIKLAEG
ARVAAFNVVGKDSDALPGTENGAAKVTPLEMYPTKGRATGGVRSQRFLKGQ-NTLILAWVG--LYPLHASTSAGSPVELPK---PDMRRDGSGVDL----
------------
>tr|A0A087B871|A0A087B871_9BIFI DNA topoisomerase IV subunit A OS=Bifidobacterium kashiwanohense JCM 15439 = DSM 21854 GN=BKAS_0511 PE=4 SV=1
------------MLSATGLIARTSENALERWSADQ-------RVKDDQIISIFRTTTRSSYGLITSAGRLIVAHVVELPVVSTDGGGVRAEELIGMIRGE
RVIAAIAMPSAVEPTPLALGTRNGVVKRWNRESP--TTMDSWSVIDLKDDDEVLAAAEARDEDRLVFVSTDSSLLTFEAKNVRPQGRTAGGMAGIRLAEG
CSAAAFAVVSKDSEALPGTENGSAKVTPLEMYPTKGRGTGGVRSQRFLKGQ-DTLVLAFVG--TYPVHASTQGGTGVELPK---PDMRRDGSGTEL----
------------
>tr|A0A0E9EXF7|A0A0E9EXF7_CHLTH DNA gyrase subunit A OS=Chlamydia trachomatis GN=gyrA_8 PE=4 SV=1
--MQLSDDPCAVALSTSGLIARTSVETFNRWS----------NVFDTPCLSVFETTTRANYALTTSAGRLVIAHVADLPHLNQGNNGVNANELLTSIRGE
KVVAAIALSDD-SKTPLAIGTKNGVVKRWNFESP--TTMDSWSIIDLKDNDSVIGAALAKDEDRIVFISSDSSLLTFDAKQVRAQGRSSAGMAGIRLNEG
CVVSAFAVVNDDSDALAGTENGAAKITPLEMYPTKGRGTGGVRSQRFLKGQ-NTLLHAYVG--NYPLYATTQRGANVELPK---PDMRRDASGTEL----
------------
>tr|W6JU36|W6JU36_9MICO DNA gyrase subunit A OS=Tetrasphaera australiensis Ben110 GN=BN11_1260009 PE=4 SV=1
-----------MLLSSSGLLARTGSADPIPA-EGG-------RAKHDAIAGAVRTSARGHFGIVTSAGRMVRVSALDLPTLVPTSGGTPAKMYVDLARGE
RILTLAGVEP-GG-PTLALGTAQGVVKRVVPDYP--LGRSEWEVIALKPGDQVVGAAQPSEQTDLVFISATAQLLRFPASSVRPQGRAAGGMAGIRLAPK
DSVVFFGVVDTASDALPGTQAGAIKVAPYEEYPPKGRGTGGVRAHRFLKGE-DVLVLAWAG--NTPARASGANGAALELPA---ATGKRDGSGFAG----
------------
>tr|K2MD00|K2MD00_BIFBI DNA topoisomerase IV subunit A (Fragment) OS=Bifidobacterium bifidum IPLA 20015 GN=B217_08441 PE=4 SV=1
--LQIDDEPCTVMLGASGTIARSTPAALDAWTSDE-------RTKDDHIVSIFRTTTRSSYGLVTSAGRLVLAHVVELPALAASPGGIPADELIGMIPGE
HVVAAIPMDQRPTPAPLAIGTRAGVVKRWNREAP--TTMDSWSVIDLKDGDSVLFAADAADEDRLVFIASDSSLLTFDAGNVRPQGRTAGGMAGIRLAEG
CTAITFNVVGKDKDALPGTENGAAKVTPLEMYPTKGRGTGGVRSQRFLKGQ-NTLIFARVG--MYPLHASTEGGSPVELPK---PDMRRDASGVDL----
------------
>tr|H0K8Q2|H0K8Q2_9PSEU DNA topoisomerase IV subunit A (Fragment) OS=Saccharomonospora azurea SZMC 14600 GN=SZMC14600_17460 PE=4 SV=1
--LEVADDPCQVILSSTGLVARTAAESEEAVRRSG-------RARHDAIAAMVHTTARGQVLLVTNRGRAFKTDVLPLPVLPQSSGGMTVRELVPLEKDE
RVVGLAPLGEQEGSPGLALGTRAGIVKVCAPDWP--VRSDEFDVITLKDDDEVVGATWTDGTETLTFVTSQASLLRYEASLVRPQGLRGGGVAGITLSKD
AQVVFFGAVDD-------ATGETVKVTPFAEYPAKGRATAGVRAHRFLKGE-TELVLAWVG--SRPVGC-SARGEAAELPE---PDPRRDGSGTAQ----
------------
>tr|A0A087D964|A0A087D964_9BIFI DNA topoisomerase IV subunit A (Fragment) OS=Bifidobacterium stellenboschense GN=BSTEL_2008 PE=4 SV=1
--LQIDDEPCVVMLSATGLIARTTPSAMDVYASDK-------RAVDDQIRAIFPTTTRSTFALVTSAGRLVLSHAVELPALPASEGGVKADELIGMIDGE
HVVAAFAMEPS-TLPPLAIGTRGGVVKRWNREAP--TTMDSWQVIDLKDGDEVLAAAPAADDDRIVFVASDASLLTFEAKNVRPQGRTAGGMAGIRLAAG
ARVLAFAVIGKDAEALPGTENGSAKVTPLEMYPTKGRATGGVRSQRFLKGQ-NTLIAAYVG--AYPLNASTDSGAPVDLPK---PDMRRDGSGTDL----
------------
>tr|L1QN82|L1QN82_9CLOT DNA gyrase/topoisomerase IV, A subunit OS=Clostridium celatum DSM 1785 GN=HMPREF0216_00224 PE=4 SV=1
-EELIVVEEVMITLSKDGFIKRIPVRTYQRSNA---KAEDIDYREGDELKYLIKSNTTENILLFTDKGNMYQTKGINIPEGKWKEKGERIDSIIKLNEEE
NIVEAISVQILDGRKSIQFITNKGIIKKSSLDKFQT-NYSKIQALKLKEDEAVIDVILLEDEDFLKVETKLGLKFSLELPILEDTPRNIMGTQLFNLIEN
DEVINVKYIDENNLVYFFTKKGMIKKTSLKEYDGNYSMWQAYKFK---Y-ENDEVISVNIVDNLNEILLISKKGMAIRFQGESVNTMGRVASGVTGISLK
EDEVISGK----
>tr|A0A0H3XJV5|A0A0H3XJV5_9MOLU DNA topoisomerase 4 subunit A OS=Spiroplasma eriocheiris CCTCC M 207170 GN=parC PE=3 SV=1
--ETIIEKDVNLWVSRDGYLKALDNSQLAKIT-----ADEFNRKPLDLWVANFSANTLDKILLITSKGNYVIIPVYKIKMSKIKDIGEHVNTISELPGEE
KIVASYLLDSFNPNITIMIATKNGMIKKVPVLDFEATRSKAMKAINLKADDEVVASQLVKDEPYVSIFTKNGFAVKYKQQEIPSLGLRTSGVKSINLKD-
DEVVGAGYGQK-ENLIFITDQNMVKKIALKELPVSTRPIKGTRLFKPNK-KLEQLIWGFIINKKETLNILHPNDEIEMFNVDKITLQ-------------
------------
>tr|A0A0C2E092|A0A0C2E092_9MOLU DNA topoisomerase 4 subunit A OS=Spiroplasma poulsonii GN=parC PE=3 SV=1
--ETIIEKNLNIWISRDGYLKALENNQLVKLT-----TEEFKRKPGDLWIADFQANSLDKILLITSKGNYVIIPVYKIKSVRIKDIGEHVNTISELPGEE
KIISAFLLNDFNPEQYIMLATKNGMIKKTAVKDFEATRSKAIKAINLKGDDEVVASQLVDKHLYVVVTTVNGFIVKYKAKEIPALGLRTAGVKSINLRD-
DTVVGAGYCKE-DTLVFITNLNAGKKITIKELPSSTRPVKGTRMFKVNK-KVTEVVWIFLAKQHDTLHMLNQQDEIMLFNTDKLNVH-------------
------------
>tr|R4U401|R4U401_9MOLU DNA topoisomerase 4 subunit A OS=Spiroplasma syrphidicola EA-1 GN=parC PE=3 SV=1
--ETIIEKDLNIWVSYDGYIKALENNQLARLA-----NEDFKRKPNDLWIADLQANTLDKLLLITSKGNYVIIPVYKIKVSKIKDIGEHVNTISELPGEE
KIIGCYLLNDFNPDNYIMLATKNGMIKKTAVPDFMATRSKAIRAINLKGDDEVVNSQLVTKQPYIIIATANGFAVKYKASEIPTLGLRTAGVKAINLKD-
DIVVNAGYCKD-DSILLLTDHGTAKRIATTELALSARPIKGARLFKQNK-KSPELVLLFIAKNKDVLNVLNANDEINVFKVDKLPVT-------------
------------
>tr|A0A0K2JH22|A0A0K2JH22_SPIKU DNA topoisomerase 4 subunit A OS=Spiroplasma kunkelii CR2-3x GN=parC PE=3 SV=1
--ETIIEKNLNIWISRDGYLKALENNQLARLA-----TEEFKRKPGDLWIADFQANTSDKILLITSKGNYVIIPVYKIKTVRLRDIGEHVNTISELPGEE
KIISVFLLNDFNKEQYIMLSTKNGMIKKIAVKDFEATRSKALKAINLKNDDEVVSSQLVDHNPYVVITTANGFIVKYHKNQIPTLGLRTAGVKSINLRD-
DVVINAGYCED-DNLVLITNLHTGKKINLKEIPTSTRPVKGTRLYKLNK-DINELLWTFLTKGKDILHMLNQNDEIEIFNTDKMPIH-------------
------------
>tr|B4F2J2|B4F2J2_PROMH DNA topoisomerase 4 subunit A OS=Proteus mirabilis (strain HI4320) GN=parC PE=3 SV=1
-QDMLPSEPVTIVLSEMGWVRSAKGHEIDPS--------TMSYRAGDSYHSAVRGMSNQPVLFLDSTGRSYSLSPNDMPS--GRSQGEPLTGKLTFPPDA
SVKYMLAGA---AKQEYLLATKEGYGSVLSYEEMETKNKTGKGLLTVSDETELLAPFLVDAEHWLVIITDKTRILAISAEHLNEMNKKGRGTRLVALGEQ
SDVIEQIVLIAKNEALTFTVDGQQQTLKAEEIPLKHHPEAVTVIMSEKGHNIDAKSVGFKTGDDQAVHLIDTTGQSYTVDVDALPS--------------
------------
>tr|A0A0G4QCZ9|A0A0G4QCZ9_PROVU DNA topoisomerase 4 subunit A OS=Proteus vulgaris GN=parC PE=3 SV=1
-QDMLPSEPVTIVLSEMGWVRNAKGHDIDPS--------GMSYRAGDSYHSAVRGMSNQPVLFLDSTGRSYTLSPNDMPS--GRSQGEPLTGKLTFPPEA
SVKYMLAGS---AGQEYLLATKEGYGTVLSYDEMETKNKTGKGLLTVSEETELLAPLLVDPQHWFIIITDKTRILAISAEQLNEMNKKGRGTRLVALGEQ
GDVIEQMLFAPKDEALIFTVDGQQEVLKAEEIPLKHHPEAVTVIMSEKGHSIDAKSVGFKSGDDQPVHLIDTTGQSYTVDVDALPS--------------
------------
>tr|S6G723|S6G723_9MOLU DNA topoisomerase 4 subunit A OS=Mycoplasma yeatsii 13926 GN=parC PE=3 SV=1
-KEVLVEKEFNLWVSKDGYIKAVDNNVLAKNDF-----DTFEKKPNDMWILTGVVSNLEHLILVSDKANYYSIPLYKISMSKWKDMGVHINTVATMSGSE
TIINAFFDN---TTQQIMIVSKNGLIKRTPIVDLKTKTFNRFKIMKLSDDDQLVSADLVTSKRYCAIVTKNAYAVRYNIEDIPVQLTSSKGVKAANLK-D
DSIVSAISLDANKDIICFTDKNTYKKIDQNQIPIYIRPKRGVKILLEKKRNKESILFSYAINDDSIIQILDNQDQITDINSNSIKK--------------
------------
>tr|A0A0L1IJG4|A0A0L1IJG4_9MOLU DNA topoisomerase 4 subunit A OS=Mycoplasma sp. HU2014 GN=parC PE=3 SV=1
-KEVLVEKEFNLWVSKDGYIKAIDNNVLSKNEL-----DTFEKKPNDMWISTGLVSNLEHLILVSDKANYYSIPLYKIAMSKWKDMGVHINTVATMSGSE
TIINAFFDN---ATQHIMMVSKNGLIKRTPIVDLKTKTFTRFKIMKLRDDDQLVSADLVTSKRYCAIVTQNAYAVRYNIEDIPVQLTSSKGVKAANLK-N
DYIVSAISLEDNRDIICFTNKNTYKRINQDQIPIYIRPKRGARILLEKKRNKENVLFSYAIDNNSIIQILDNQDQITDIYTNSIRK--------------
------------
>tr|L5L8G9|L5L8G9_9MOLU DNA topoisomerase 4 subunit A OS=Mycoplasma feriruminatoris GN=parC PE=3 SV=1
-KEVIVEKEINLWISKDGYIKVIDNNVLSKNEM-----SLFGKKPNDMWISQGVCSNLDHLILISDQANYYSIPVYKIQQSKWKEQGVHINSVATTQPNE
TIINAFFTN---STQHLLLVTKNGLIKRTQISDLETKIFNKFKIMKISDDDSLVYADLVSSKSYCSIVTKNGYAVRYNIEDIPVQSTISKGVKAANLK-D
DYIISALSLDNNKDILIFTNKNNYKKLDQNLIPIYIRPKKGTRILVEKKKNKEEVLFGFATSNDMVVSILDQNDQIIDINVNDLKH--------------
------------
>tr|M9WH27|M9WH27_9MOLU DNA topoisomerase 4 subunit A OS=Mycoplasma putrefaciens Mput9231 GN=parC PE=3 SV=1
-KEVLVEKEFNLWVSKDGYLKAVDNYALAKNEL-----STFGKKPNDMWISSGVVSNLEHLILVSNKANYYSIPLYKVTMSKWKDMGVHINTVATMDSNE
TIINVFFDS---ATQHVMLASRNGFIKRTPIVDLKTKIFNRFKIMKLSGDDELVSASLVASKRYCAIVTKKGFGVRYNIEDVPIQMTNSKGVKAANLK-D
DQIVSAISLEQDKEIICFTDKNHLKKIAQTQLPIYIRPKRGTRIILEKKRAKENIIFSHAIANDSIIEILDSSDQITELQASTIKT--------------
------------
>tr|C7LMV1|C7LMV1_MYCML DNA topoisomerase 4 subunit A OS=Mycoplasma mycoides subsp. capri str. GM12 GN=parC PE=3 SV=1
-KEVIIEKEINLWISKDGYIKVIDNNILNKNEL-----SSFGKKPNDMWISQGVCSNLDHLILVSDQANYYSIPLYKIANSKWKDQGVHINSVATTQPNE
TIINAFFIN---STQHLLLVSKNGLIKRTQISDLETKIFNKFKIMKISDDDSLVYADLISSKSYCCIITKNGYAVRYNIEDIPVQSTISKGVKAANLK-D
DYIISALSLDNNKDVLIFTNKNNYKRLDQNLIPIYIRPKKGIRILVEKKKNKEQVIFGFAINDQMSISILDTNDQITDINVSDLKH--------------
------------
>tr|Q6F1F6|Q6F1F6_MESFL DNA topoisomerase 4 subunit A OS=Mesoplasma florum (strain ATCC 33453 / NBRC 100688 / NCTC 11704 / L1) GN=parC PE=3 SV=1
-KEVLVEHEYNLWISKDGYLKAIESKLISKNDP-----AVFGRKPNDMWIAAGEVSNLQHLILVTNKGTYYSIPLYKLPMSKWRDMGVHVNTIATMDPSE
HIVSAFFAE---ALQQILITSKNGNIKRIPVKDLETKIFTRFRIMKLDAVDEIVSASLITSKRTCGIITRNGYGVRYHIEDIPVQGTNSKGVKAANLK-E
DYIVAGLGLTSEDTIMYLTEKDGVKKFRNEDLPIYIRPKRGIRVLPERKRGTEYITFAFNANEENIIKAIDTQDMYQEVNVNKYRH--------------
------------
>tr|R7GEX1|R7GEX1_9CLOT DNA topoisomerase IV A subunit OS=Clostridium sp. CAG:307 GN=BN598_00318 PE=4 SV=1
-QDLIQKEQNYFVATKDGYLKRVSIKNYNLSKL-------NTIKEKDSIVFEGEVSTTDVMLGFTNLGNFVYIPIFKVDECKMKDVGSYINNIATISPIE
KLIRVFIISKFDDKTNLLLTTKNGLIKQTLLNDFVVSRYKAVRAMKLQENDELISVDMTTNPLEIVCLTHECDALRFRASDVALYGTTAGGIKAIALKPS
DYLVSAFYTNKNDDMLLLTKRGTLKRMPVNDLNLSKRARAGQPVIKKIKSNPHYLVDAKSMT--------------------------------------
------------
>tr|F7MRN0|F7MRN0_CLOBO DNA topoisomerase IV subunit A (Fragment) OS=Clostridium botulinum C str. Stockholm GN=CBCST_17529 PE=4 SV=1
---------------------------------------------------LLNGNTKDNMMIFTDEGNLYQIRISNIPEMKWKEKGERLDTLIKLDEKE
KIIDIYITSELLPSKSFMFFTNRGVIKKSSLDKFKT-NYSKLLALKLKDNEKLIDIKLVNTEKYISVITKNGLSFTVDIPRIEDSERNIMGTQIFNISDN
DEVKSIKYIDKSTSVYFFTKSGYVKRTNLQEFNAENPCIKGYKLKK----EQDKIINVLLFNDKKDIILITKNAMGIRFEANSISYMGKIASGVTGISLR
DNEVIF------
>tr|D9SPV6|D9SPV6_CLOC7 DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium cellulovorans (strain ATCC 35296 / DSM 3052 / OCM 3 / 743B) GN=Clocel_2376 P
-------ERFVQILTSQGLTFTVNEPKLDDSDRMIQGTMLATIPAKDSIEKAEYTDSEARLIIITSEGNVLNIASNVLENVT--E-PFNIVNSFGIDKSN
KFIGIINVSDFKEDSYIIFFSKRGYVKKTSLKEYQGE-YLCSQGYKLKNDDELVGA-SLINAENFVLVTQKGMAIRVNCNDVNEMGKIASGVIGISLKDE
DFVIYGNTISDNDYIKITTKNKEEKDYNLSDLPIQNRATRGKNIFIA-----------------------------------------------------
------------
>tr|A0A0H3J1N5|A0A0H3J1N5_CLOPA DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium pasteurianum DSM 525 = ATCC 6013 GN=gyrA2 PE=4 SV=1
-------EKFLKIETELNFKFTIEEPVIEESERNSLGNKLFNLSDKDSIISVHNTDSESTLLFFTNRGKLLYVPAFLLQNID--KEGINIDKVNGFEEGE
KILNVISVKDFKENIDTYFFTGNGLIKKTALEDFKTE-NSSTVVYKFRGDI-LVNVEFMDEDNDIIIITLKGMGIRFSSQNISHMGRIASGVTGISLEEE
DEVLKGFLCNEVYCVEIKSKNKEKKIIPLEDFKIQNRAGRGKNIMLV-----------------------------------------------------
------------
>tr|R6KG09|R6KG09_9CLOT DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium sp. CAG:265 GN=BN573_00479 PE=4 SV=1
-------GQFLEVKSKLGLEFKLQVPVIEDMQRNVLGQQLFNLTADDEVVEVANTDNLSDLILFSNKGNVYKVKGFLLTKIN--EKEIPLTSLVDFSKGE
IIIDIYSIKDFTMEKMLYFFTKKGMVKKTALSEYGGE-YLVQQGYKFKYEDEIIAVRMADDLSDVIIVTKGGMAIKFSSENVNSMGRIASGVTGISLRDG
DEVISADVKENHEIITLISKNKEKKEIKMTDIKLQNRAGRGSIIMVT-----------------------------------------------------
------------
>tr|B2TLD4|B2TLD4_CLOBB DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium botulinum (strain Eklund 17B / Type B) GN=gyrA PE=4 SV=1
-------NDYLNIKTKLELEFTIEVPELENVPRNILPIQLFNLSIDDEIVEVNKINSSKTLLLFSNKGYIYKIPGFLLKNIM--NGDIKLEVFTGLEKKE
KIIRISSISSYDDDLALYSFSKKGLVKKTLLNEFSVD-TQKQFFYKLKTEDEVISVDINNILGNLVIITKKGMAIRFPVENVNSMGKVASGVTGISLREE
DEVIFGAYVSKYLEISLTSKANDKVNITVEDIKLQNRAGRGTNVMLM-----------------------------------------------------
------------
>tr|A0A0A7FTV1|A0A0A7FTV1_9CLOT DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium baratii str. Sullivan GN=gyrA PE=4 SV=1
-------KEFLKVNTKIGLEFNLEIGEVLDTPRNIMGSYLFNMSDNDEVISCEYTDTLSDLLLFTDKGNVVKIKSFMLESVV--SKDIKLNDIVSLLEKE
RVIKIVSLKEYNEDLAVFVITKRGLVKKTILTEFSHD-FTITQYYKFKFDDEIASITINNQYGELVIITKKGMAIRFNQSNINPMGRIASGVTGISLKDN
DEVLYGRYIIESGVFTLTSLKKNVETVKISDIKLQNRAGRGTDIMVV-----------------------------------------------------
------------
>tr|U5RX92|U5RX92_9CLOT DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium autoethanogenum DSM 10061 GN=CAETHG_3014 PE=4 SV=1
-------VEFIKVETKSGLEFTVRSPEINLEDRNIVTTPLVTLQGEDFAVKMDFTNSSSYILIFTLDGEVLSIPAFMLQNVD--NSGIDIKVLMKIDVG-
NILKIISVENFDC-GYVYFFTQYGMVKKTALMEFKQI-AGCSTAYKFKDKDSLVNV-EYSKEIEIFLITERGMGIKFKANTVNTMGKLAAGVTAISLKED
DKVAYCFLIDGNDKLNLISEKGNKEQINVKDVVIQNRAGRGKSIMLI-----------------------------------------------------
------------
>tr|Q97IL2|Q97IL2_CLOAB DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787
-------EGFIKVSTEKGLDFTVREPLIEEMDRNKMGHQCISVCPMDRIVSSEDTTTSSTLLIFIDDGRVINIPSYMFKNMD--DKVLNLSELYCFNSNN
KIIKTLSIEEFNENKFIYFFSSKGFVKKTKLSEFVES-KGIEVCYKLRNKD-MLVNVDVSNEEEVVLITKKAMGIKFLSSSVSVMGKIASGVTGISLNEE
DITEYGFVVKENLKIILKSKLNDKIEVEIEDIKVQNRGGKGKNLTTL-----------------------------------------------------
------------
>tr|M1N4I8|M1N4I8_9CLOT DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium saccharoperbutylacetonicum N1-4(HMT) GN=gyrA2 PE=4 SV=1
-------QKFLRVKSKLGLEFTLEVKALEDTSRNILPMQLFNFPKEDEIIEVEKTNSLKEILMFSNKGFVYKVPAFLMKKVL--KEEIEVEAFLGLEKGE
KIISLKSIDSYTEDLAVYTFSKKGMIKKTLLKEFEGD-FFKQVCYKFKYEDEVISTEVEQLFGHLIMITKKGMAIRFPVENVNTMGKIASGVTGISLRDE
DEVIFGKYHSNYKEVMLVSKSKEKSVLKINDIKLQNRAGRGANIMVI-----------------------------------------------------
------------
>tr|U6EWY0|U6EWY0_CLOTA DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium tetani 12124569 GN=BN906_01914 PE=4 SV=1
-------EKFLKLSTKMGLDFTIEEPTIDEEDRNILSNIFCSLGYKDKVIKSQEVDSNKKLLIFLKNGEVIKINCNMLQNLE--GKAINIFDLLEYQQKN
EIINVLPFDCNDKDWEIYYLTKCGLVKKTLLKEFQGD-YFITAGYKFRDKDEIIAVDFGKHEKDIIIISQKGMCIRFSKNSINPVGKIASGVMGINLKKE
DKVLYGFINIES-NMILTFKEGKDEEIKLKDIISQNRAGKGNSILNA-----------------------------------------------------
------------
>tr|N9WGU5|N9WGU5_9CLOT DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium colicanis 209318 GN=HMPREF1092_01541 PE=4 SV=1
-------EDFLRVKTALGLEFQLEIGEIKHQPRNILGTYLFNLSKEDKVIEYEYTDTLSDLLLFTDKGNMFKIKTFLVQNVI--KEDLKLSDVIDLEKDE
KIIKITSIKNYTEELGVYAVTKKGIIKKTSLKEFDGD-YVTQGYYKLKSSDRVIMVLISPLIGNIVMVTKKGVTIKFPVDGVSAMGKFTSGVTGITLKDG
EEVVYAKYMENDE-LSVTTKNKKEDIIIVGMLKLQNRAGRGASVVEL-----------------------------------------------------
------------
>tr|V9H7X9|V9H7X9_9CLOT DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium sp. 7_2_43FAA GN=CSBG_02037 PE=4 SV=1
-------KEFISFETKEGLSFSLQIPKIEDLPRNILPTIMFNLSNKDEIIKVESTDSLSNVLMFTNKGKVFKIPAFLLSGVS--KGELPLDKIVDIEKDE
KVIKVFSLKTFEENKFIYFFTRRGMIKKTALTEFDGN-YSTQITYKFKYDDELISVELYDDQVEMLIITKKAMGIKFSSENVNTMGKVASGVTGISLKEN
DEVIYGSLIGSQSKITLISKNKEKKEVELEDIKLQNRAGKGSSIMTI-----------------------------------------------------
------------
>tr|A0A0G9L7S1|A0A0G9L7S1_CLOBE DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium beijerinckii GN=AAT22_14065 PE=4 SV=1
-------KEFINFETKKGLVFNLPIPSIEDSARNILPIMMFNLSNKDEVTKVEKIDSLSNILIFTNLGKVFKIPAFLLSGVN--KGEIPLEKIIDLEKNE
KIIKVISIKNFEDNRFIYFFTKKGMVKKTSLVEFDGN-YSSQLSYKFKYDDELISAEMYNNVAEIVIITKKGMGIKFSSENINTMGKVASGVTGISLKEN
DEVIYGKIIAIQYKIILVSKNKEKKEVDIEDIKLQNRAGKGSNIITI-----------------------------------------------------
------------
>tr|A0A0B5QGA7|A0A0B5QGA7_CLOBE DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium beijerinckii GN=LF65_04846 PE=4 SV=1
-------EKFLKVKSKLGLEFTLEIKNLEETARNILPTQLFNFSEEDEISQVEKTNSLKELLIFSNRGYVYKIPVFLMRNVL--NKEINLEAFIGMEKGE
KIISLISIDSYDEDLGVYTFTKKGMVKKTLLKEFEGD-FLRQACYKFKFEDEVVSVEVNQIIGHLIMITKKGMAIRFPVENVNIMGKIASGVTGISLRDE
DQVIFGKYHSNYKKITLVSKGKERSVMDISDIKLQNRAGRGTSIMMV-----------------------------------------------------
------------
>tr|S6EPL6|S6EPL6_9CLOT DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium chauvoei JF4335 GN=CCH01_005110 PE=4 SV=1
-------KDFLKVETKNGLNFSLEIPELEDQPRNILPLQIFNLSSKDEILNVENTDSKSDILMFTNKGSVYKISAFLLQNVN--KGDIILSNIVDMLPGE
SVIKISSVINFIDNKYVYFFTKKGMIKKTLLKEFEGN-YSSQIAYKFKHDDEVISVDICDKNAEVIMVTKKAMAIKFSTENVNPMGKVASGVTGISLKED
DEVIFGRVFVNNHKLTLISKSKNKKELEIEEIKLQNRAGRGSSALMI-----------------------------------------------------
------------
>tr|A0A0A6PYU7|A0A0A6PYU7_CLOBU DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium butyricum GN=OA81_08385 PE=4 SV=1
-------SKFLKFTTRNELEFTLEIPEVEDATRNILPTQLFNLPEDDIVVDVNKTKSTEQLLIFTNTGFIYKVPVFMMKNIF--TKDMSIDQFIGIGRNE
KIIRIASVASYDEERCIYTFTKTGMVKKTLLKEYEGD-FFKQPCHKFKYEDELVSVDIDKILGYLIMVTKKGMAIRFPVENVNSMGKIASGVTGISLKDD
DEVIYGKYYSNYIELILTSKSKTKTEVRIRDIKLQNRAGRGTSVMML-----------------------------------------------------
------------
>tr|G7M9Z9|G7M9Z9_9CLOT DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium sp. DL-VIII GN=CDLVIII_5047 PE=4 SV=1
-------PKFLKFKSKLGLEFTLEVKKLEDTSRNILPIQLFNFAQDDEIIEVQKTNSLKELLMFSNKGYVYKVPVFLMKNVL--AGEVPVEAFLGLQKGE
KIISITSLDSYDDELGVYTFTKKGMIKKTLLKEFEGE-FFKQVCYKFKFEDEVISVEVNQAFGHLIMITKKGMAIRFPVENVSAMGKVASGVTGISLRDE
DEVIFGKYHSNYIQIVLASKSKKKSVVKINDIKLQNRAGRGASIMMI-----------------------------------------------------
------------
>tr|K6TIL8|K6TIL8_9CLOT DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium sp. Maddingley MBC34-26 GN=A370_05197 PE=4 SV=1
-------NKFLRIKSKLGLEFTLEVKNLEDTSRNILPTQLFNFSEEDEIEYVEKTNSLRELLMFSNKGYVYKIPVFLMKNIL--NGEMPVEAFLGLEKGE
KIISLVSIESYDDEYGVYTFTKKGMVKKTSLTEFDGD-FFKQVFYKFKFEDEVVSVEVNKAFGHLIMITKKGMAIKFPVENVSAMGKIASGVTGISLREE
DEVIFGKYHSKYTEVVLVSKAKEKSIIKVDEIKLQNRAGRGTNIMVI-----------------------------------------------------
------------
>tr|U5MWJ7|U5MWJ7_CLOSA DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium saccharobutylicum DSM 13864 GN=gyrA2 PE=4 SV=1
-------EGFLRVKSKLGLEFTLEVPKLENATRNILPVQLFNLSPNDEVIEVQRTDSLKELLLFSNKGNVYKVPVFLMKNII--AGEIPLEFFLGLEKNE
KIISLFSTNSYEEELGIYVFTKKGMVKKTLLKDFEGD-CFRQGFYKFKFEDEIVSVDINRLLGYLVMITKKGMGIRFPVENVNAMGKMASGVTGISLRDE
DEVIFGKYNSNYIEVILTSTEKEKCLVKINDIKLQNRAGRGTNVMML-----------------------------------------------------
------------
>tr|A0A0L8EYP5|A0A0L8EYP5_9CLOT DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium sp. DMHC 10 GN=AGR56_06360 PE=4 SV=1
-------EKYIEITTELGLSFKLEEPSIEEADRNVMSYTMFNLSSKDRVVNINITSTTEKILIFTNKGAVIRVPAFIIENIS--KEGISISTICDFTEDS
KVVGIISVKKFDEGKYIYFFSKNGFVKKTALSEFDGD-YLTTPCYKFRNED-ELINAELGEESDIILVTEKSMCIRFQNNSVNPMGRIASGVTGISLNED
DFVKYGFILKKEFKMSIKSKLGEEKEILFENIKEQNRGGKGKSLMVD-----------------------------------------------------
------------
>tr|A0A099S6C5|A0A099S6C5_9CLOT DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium sp. HMP27 GN=DP68_10225 PE=4 SV=1
-------EQFIHVKTALGLNFTLEEPKLESVDRNILPQQMFNLSSQDEVVEIESTNSLDKILLFLSNGEVIRIPAFMLQNIP--DKSINLLEMMQNLKEV
NILNVIALNSKT-FDEVLFFTKKGLVKKTSLQEFNQD-YSITTSYKFKAEDALLAIDFASDKSDIIIITKRAMCIRFDKESVSPMGRVASGVTGISLKDG
DEVLFGAVIDDE-ELHLISKHENETKLDIASTKPQNRAGRGNNIMLL-----------------------------------------------------
------------
>tr|R4KBB2|R4KBB2_CLOPA DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium pasteurianum BC1 GN=Clopa_2994 PE=4 SV=1
-------EKFLTIETKLNFQFTIEEPILEESERNNFGTKLFNLPNKDSITRVENTDSSSTILFFTNTGKLLYIPALFLQNMD--SEGINIEEINEFDGKE
KILNIISVKDFKELIDVYFFTKNGLIKKTALEEFKME-NTSTIAYKFRGKT-LINVEFLNEDNDIIIITLKGMSIRFLSKNISYMGKIASGVTGISLDEE
DEALYGFLCREEYVVTVKSKNKESKVIPLEEFKLQNRAGRGKNIMLV-----------------------------------------------------
------------
>tr|U2CK51|U2CK51_9FIRM DNA topoisomerase (ATP-hydrolyzing) OS=Clostridiales bacterium oral taxon 876 str. F0540 GN=HMPREF1982_03629 PE=4 SV=1
-------NGFIKVITEKGLTFAVEEPHLDAADRNIASTILAAIPPKDKVVSTEFSYSKEDILIFLEDGNVLKLQTNLFSGLE--DREIRLQDLFDISSDI
KVLNILKTNKCEEPISVYFFTKNGMIKKTLLDEFKGD-YLTALAYKFKNDDKLIAVDFLSENKDIFVVTKRALGIRFRGSDVPSMGRAAAGVIAISLKED
DEVLFGSIINSSSEVQLTTNKKNKKSINLGSIKLQNRAGRGLSLMLI-----------------------------------------------------
------------
>tr|A0A0H2YRF7|A0A0H2YRF7_CLOP1 DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237
-------ERFVEIETTNGLNFVVSEPELEFTDRNILGVQLVPLKSGNQIKSIRKVNSFRNIIAFSNKGKVFKFPAYLLQNTE--E--SNISDLVDFEKDE
IIIKVAPINEFGEDLFVYFFSREGLVKKTSLREFLGE-FNNQIAYKFKTPDELVNVDINFENATVILVTKNGMGIKFLATAINPMGRVASGVTGISLKDD
NKVIFGKVIPPSEKLILESKQKEKAEVNIEDIKLQNRAGRGSSLMIL-----------------------------------------------------
------------
>tr|V7I8V8|V7I8V8_9CLOT DNA topoisomerase (ATP-hydrolyzing) OS=Youngiibacter fragilis 232.1 GN=T472_0200090 PE=4 SV=1
-------PMFVRILTNRGLDFTVPEADVQIKDRMIVPDQFLTMPPQDEIARVHTGASYLSLVAVTSLGAYCKIPMYLFENLQ--E-PITLSDLYGMMKGE
RVVGVFTMEDE-DDREVYMATEGGLVKRTPISDFVGD-SMSGSVIRFKEPDRLAYAGAFPSSASMLMVTEKGMAIRFETESISLLSKNASGVVGINLKEE
DRVFFASVVTTEKELVLSSKGFPDKKVPLEDIKLQNRAARGKNVFMV-----------------------------------------------------
------------
>tr|E1IGI9|E1IGI9_9CHLR DNA gyrase subunit A OS=Oscillochloris trichoides DG-6 GN=gyrA PE=3 SV=1
-------HDNLLFFTDKGKVYQLKAHEVPDSARTAKGLPLVNLDPGEQVTSMLAVPDGEYLVMATHRGKIKRTQLSEYSQVRSNGL-----IAIGLEEGD
VLGWVRVSN---GHEDVLMTTVKGQTIRFQQQAVRSMGATGVNGINLSEGDRVISMELAIPDSDLLVVTARGFGKRTELGDYPTKGRATGGVITIRLRPG
DEA-GAAIVNQRSLLTFVTAAGVVMRTSAGEISQLSRATQGVTVVNPDDG--DRVAALSVEE--------------------------------------
------------
>tr|A0A0G1YZV5|A0A0G1YZV5_9BACT DNA topoisomerase (ATP-hydrolyzing) OS=Parcubacteria bacterium GW2011_GWF2_50_9 GN=UY62_C0047G0001 PE=4 SV=1
-------HNDLLFFTDMGKAYQIKMYEIPEARRATKGKSVMNFGAEEKVTSILPMPKALSLLMITRAGIGKKTKAASFHDVRRSGL-----IAIKLKAGD
ELVSASFVE---KGDEAVLVTGKGQSIRFKVSDIREMGASGVKAMRLKKGDTIVGTGIIGKHPELLVIMKNGYGKRTKLKEYKTQKRGGSGVKTAKISSK
TGLIAAHVITSNEEVVAISRKSQVIRTDVKGIATLSRQTQGVRIMKLREG--DSIASLTCL---------------------------------------
------------
>tr|A0A0G1VGU9|A0A0G1VGU9_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWA2_47_64 GN=gyrA PE=3 SV=1
-------HNDILLFTDKGKAFQIKMYEIPEGRRATKGKSVMNFAADEKVTSILPMPKKLSLFMMTKNGVGKKTAAASFHDVRRSGL-----VAIKLKFGD
ELVSASFVE---KGDEAILVTGKGQSIRFKESDIREMGASGVRAMRLRKGDSIVGTGIISRHPELLVIMKNGYGKKTKLKEYKTQKRGGSGVKTAKITSK
TGLIAAHIVTSEEEVVAISRKSQVIRTGVSEIASLGRQTQGVRIMKLREG--DSIASLTCL---------------------------------------
------------
>tr|A0A0G1UKF3|A0A0G1UKF3_9BACT DNA topoisomerase (ATP-hydrolyzing) OS=Parcubacteria bacterium GW2011_GWA1_48_11b GN=UY24_C0012G0007 PE=3 SV=1
-------HDNILFFTNTGKVFQTKGYDIPEASRQSKGKAIVNFSPTDMITAVIPISKKGYLFMATANGVIKKVDLDAFAQVRRNGI-----AAIKLKGDD
QLGWVLSTS---GNDQIMLVSAEGNSIRFKEKDVRPMGAGGVIGIRLDKGQKVVGADVIPSGLRILVVMANGYGKRTDLKFYKLQKRGGHGIKTAKITPK
TGLVSAHIISENKDLIALSRKGQVIRTTVDSISVLGRATQGVRVMRLDSG--DGLASVVVF---------------------------------------
------------
>tr|A0A0G1FZT2|A0A0G1FZT2_9BACT DNA gyrase subunit A OS=Parcubacteria (Yanofskybacteria) bacterium GW2011_GWA2_44_10 GN=gyrA PE=3 SV=1
-------HDNLLFFTNTGKVFQTKGYEVPESSRQAKGKAIVNFSPSDLITAVVPVPKKGYLFMATAKGVIKKVEMDSFEKVRSNGI-----AAIKLKDDD
QLGWVITTS---GNDQIIMVSSGGNSIRFKEKDVRPMGASGVIGMRLDKDEKVVGADAVPSGLKILVVMSNGYGKRTDLRFYKVQNRGGRGIMTAKITTK
TGLVSAHIVSENKELVAVSQKGVVIRTSIESVSVLGRATQGVRVMKVESG--DHLASVALV---------------------------------------
------------
>tr|A0A0G0QWK6|A0A0G0QWK6_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWC1_39_29 GN=gyrA PE=3 SV=1
-------HDSVLFFTNSGKVFQTKGYEVPEASRQSKGRAIVNFSPTDVITAVVPIPKKGFLFMTTANGVIKKVDIDAFSSVRKSGM-----IAIKLKTSD
ELKWVLTTS---GNDQVMLVTSDGNAIRFKEKDIRPMGAGGVIGIRVDKNSKVVGADVVPSGLKVLTVMENGYGKRTDVRFYKVQNRGGKGVMTSKITSK
TGLVSGHITSENKELIAMSKKGQTIKTEISSVSILGRATQGVRIMRMEAG--DSIASTVVA---------------------------------------
------------
>tr|A0A0G0QQP1|A0A0G0QQP1_9BACT DNA gyrase subunit A OS=Parcubacteria (Yanofskybacteria) bacterium GW2011_GWE2_40_11 GN=gyrA PE=3 SV=1
-------HDSVLFFTNSGKVFQTKGYEVPEASRQSKGRAIANFSPSDVISAVVPVPKKGFLFMTTAKGVIKKVDIDAFSAVRKSGM-----IAIKLKNED
QLNWVLTTS---GNDQIILVTNSGNAIRFKEKDVRPMGASGVIGIRVEKGEKVVGTDVIPAGLKLLAVMENGYGKRTDLRFYKVQNRGGRGIMTAKITPK
TGLVSAHVTNENKELIAMSKKGQSIRTSIDSVSILGRATQGVRVMKLEAG--DVVMSTVVA---------------------------------------
------------
>tr|A0A0G1XJ96|A0A0G1XJ96_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWA1_49_11 GN=gyrA PE=3 SV=1
-------HDDILFFTNSGKVFQTKGYEVPESSRQSKGKAIANFAASDIITAVVKVPKKGFLFMATANGVIKKVDMDAFAKVRSNGM-----AAIKLKGDD
QLGWVITTS---GSDQIVMVSSGGSAIRFNEKDVRAMGAGGVIGMRLDAKEKVVGADVVPSGLKVLAVMSNGYGKRTELRYYKIQKRGGRGIMTANLTPK
TGLVSAHVTSENKELIAVSRKGVVIRTDISTVSILGRATQGVRVMRIEPG--DALASVVVV---------------------------------------
------------
>tr|A0A0G0MQ44|A0A0G0MQ44_9BACT DNA gyrase subunit A OS=Parcubacteria (Yanofskybacteria) bacterium GW2011_GWA1_39_13 GN=gyrA PE=3 SV=1
-------HDSLLFFTNSGKVFQTKGYEVPESSRQSKGKAIVNFSPSEIITAVVPIPKGGYLFMATANGVIKKVDADSFSQVRSNGM-----IAIKLKGND
ELGWVLSTT---GNDQVMLVTSGGNAIRFKEKDVRPMGASGVIGVRMDKDEKVVGADVVPSGLKILVVMGNGYGKRTDLKFYKIQGRGGRGIMTAKITPK
TGLVSAHITSENKELIAVSKKGVVIRTSIDSVSVLGRATQGVRVMRVEAG--DGLASVVVV---------------------------------------
------------
>tr|A0A0G1TP53|A0A0G1TP53_9BACT DNA topoisomerase (ATP-hydrolyzing) OS=Parcubacteria bacterium GW2011_GWA2_47_8b GN=UY12_C0033G0003 PE=4 SV=1
-------HDNVLFFTDRGRVFQTKVYEIPAGTRTSKGKPIHNFPVEEKISALITYEKDGNLIMVTKKGLVKKTSLKGFDNVRRTGI-----IAIGLKKDD
QLNWVRLSP---GGDDVIITTALGQSIRFQEAKVRAMGAAGVRAIKLKGKDQVASMDLIPKDSRLLVVMANGYGKQTPLSQYKTQGRGGSGIKTAAITAK
TGLVAAAVLGA-EEVLALSTKGQIIRTQLATIRKASRATQGVRIMTLDSG--DKVAGIVIL---------------------------------------
------------
>tr|A0A0Q5VA96|A0A0Q5VA96_9ACTN DNA gyrase subunit A OS=Geodermatophilus sp. Leaf369 GN=ASG36_09385 PE=4 SV=1
-------HDWILFFTNKGRVYRAKAYELPEAARTARGAHVANIQPDEKIAQVIQIKDAPYLVLATANGQVKKTRLADFDSPRSGGV-----IAINLRDGD
ELVGASLID---PEQNLLLVTSRAMSICFKADQLRPMGTEGVRGISLSDDDRLLSMIVVT-GVDVLVATEGGYAKRTGIENYPEQNRGGKGVLTADPKSR
KGLVGALSVVLGDELYAITSTGGVIRTPVNGVRHKDRATMGVKLMNLPED--VTIVAIARTT--------------------------------------
------------
>tr|A0A0N9HRU4|A0A0N9HRU4_9PSEU DNA gyrase subunit A OS=Kibdelosporangium phytohabitans GN=AOZ06_00030 PE=4 SV=1
-------HDWILFFTNKGRVYRAKAYELPEASRNARGQHVANLQPEEHIAQVIQIKDAPYLVLATKDGLVKKSKLADFDSNRSGGL-----IGINLREGD
ELVGAVLCS---ADDDLLLVSAGGQSIRFHASALRPMGTSGVLGMRFNSGDELLTLGVVR-GTFVLVATDGGYAKRTPIEDYSVQGRGGKGVLTIQHDSR
RGLVGALIVEAQDEIYAITSAGGVIRTSAGQVRKAGRQTKGVRLMNIGEG--TLLVAIARSA--------------------------------------
------------
>tr|A0A0G0JFF4|A0A0G0JFF4_9BACT DNA topoisomerase (ATP-hydrolyzing) OS=Microgenomates (Daviesbacteria) bacterium GW2011_GWA2_38_24 GN=US86_C0005G0014 PE=4 SV=1
-------LDNLLFFTDKGRVFQIKVWEIPESSRVAKGQAIVNLEQGEKVTAMLTTRSTKFLFMGTVNGTVKKTPIEEYANIRKNGL-----ISIKLDSDD
LLKWVVPTI---GDDAIILVSKEGQSIRFSERDVKATHTSGVRGIKLGKGDQVTSMNLASDTYELLVVMENGLGKKTKISAWKLQGRGGTGIKAAQVTSK
TGIVAAEIVEYSNTLVLTSNKGQLIKLNIKDVPLLQRQTQGVILMRVKTG--EKIVAGTIVS--------------------------------------
------------
>tr|K2DAM6|K2DAM6_9BACT DNA gyrase subunit A OS=uncultured bacterium (gcode 4) GN=gyrA PE=3 SV=1
-------LDNLLFFTDRGRAFQIKVWEIPEVSRIAKGQAIVNLEQGEKVTAILTLRSVKFLFMGTKMGNVKKTPVEEYANIRKNGL-----ISIKLDSGD
TLSWVVPTT---GKDDMIIVSRKGQSIRFGEHLVRPTHTSGVRGISLSKTDEVVSMNKVEDNSDLLVVMENGLGKKTKINAWKRQGRGGSGIKAAQVTDK
TGIVTAEIIDKVDTLVMTSNKGQLIKLNLKDVPTLQRQTQGVILMRVRAG--EKVAAATVVS--------------------------------------
------------
>tr|I0L0A5|I0L0A5_9ACTN DNA topoisomerase (ATP-hydrolyzing) OS=Micromonospora lupini str. Lupac 08 GN=gyrA PE=4 SV=1
-------RGRVLLVTSAGRAFKIDVLPLPVLPEQAGGMSAAELEAGETVVGLAPLGGSPGLALGTRQGVVKVCAPE--WPVRSDEF-----DVIGLRDGD
EVVGATWTD---GAETLTFVTSEASLLRFAAGMVRPQGGGGMAGINLPAGARVVFFGAVRTHGEPMVVTSTGTVKVTPFKAYPAKGRATGGVRAHRFLKD
ETVAVAWVGPR---PVGATGTGEPVELPA---ADPRRDGSGFAVML---G--PTVVGHLIER--------------------------------------
------------
>tr|F4FH78|F4FH78_VERMA DNA topoisomerase (ATP-hydrolyzing) OS=Verrucosispora maris (strain AB-18-032) GN=VAB18032_13720 PE=4 SV=1
-------RGRVLLVTSAGRAFKVDVLPLPVLPEQAGGMSAAELEPGESVVGLAPLGPSPGLALGTRQGVVKVCAPD--WPVRSDEF-----EVIGLRDGD
EVVGATWTD---GAESLAFLTSAASLLRFPAGTVRPQGGGGMAGVALPDGAQVVYFGAVRTHGEPMVVTSTGTVKVTPFAAYPAKGRATGGVRAQRFLKG
ETVVVAWIGPR---PVGSTANGEPVELPT---ADPRRDGSGFAVML---G--PTVIGHQIDR--------------------------------------
------------
>tr|A0A0J6VG75|A0A0J6VG75_9MYCO DNA gyrase subunit A OS=Mycobacterium obuense GN=gyrA_2 PE=3 SV=1
-------HDWILFFTTQGRVYRAKAYELPEASRTARGQHVANLQPEERIAQVIQLKTAPYLVLATRNGLVKKSRLVDFDSNRSGGI-----VAVNLRDGD
ELVGAVLCS---SENDLLLVSANGQSIRFSATALRPMGTSGVQGMRFNGDDALLSLNVVQ-DTYLLVATSGGYAKRTAIDEYPVQGRGGKGVLTIMFDKR
RGLVGALIVDDETELYAITSGGGVIRTAARQVRKAGRQTKGVRLMNLGDG--DTLIAIARNA--------------------------------------
------------
>tr|H5SU06|H5SU06_9BACT DNA topoisomerase (ATP-hydrolyzing) OS=Candidatus Acetothermus autotrophicum GN=HGMM_OP4C642 PE=4 SV=1
-------RDDLLIFSKAHKAYKLKAYQLYSERRDVKGENLRNFEPDEEVCAMLPLHTHRYCLMATAQGILNRNEYADFYNAHTSGI-----LAINAEPGD
YIVDAALSK---GTGEVILASAQGMTIRFREELARCTGSKGVIGMRLDAGDRLVGLVTLEPEDKLLLVTENGYGKRTPLEEFPSQGRGGKGVLGIKVDEK
TGIVAIEKVKDDDEIMVTTLNGKIIRISAGEVRIVGRYAKGVKLIDLDEG--DKVVSVVRYV--------------------------------------
------------
>tr|D3RUQ2|D3RUQ2_ALLVD DNA gyrase subunit A OS=Allochromatium vinosum (strain ATCC 17899 / DSM 180 / NBRC 103801 / NCIMB 10441 / D) GN=gyrA PE=3 SV=1
-------HDTVLCFSSRGRVYWLKVYELPQAGRGARGRPMVNLEAGERITTLLPVRDGSFVFMATSAGTVKKTPLKDFSRPLSRGI-----IAIDLREDE
LLVGATITG---GEQDLMLFTSAGKAVRFSESHVRSMGAHGVRGVMLQEGQRVIALVAPEDGGTVLSVTENGYGKRTDVDQFPTKGRGTQGVIAIDTAER
NGQVGAILVHPGDEIMLIADDGTLIRTSVDQIPVVGRNTKGVKLINLGEG--QRLVFVERIA--------------------------------------
------------
>tr|W0E165|W0E165_MARPU DNA gyrase subunit A OS=Marichromatium purpuratum 984 GN=gyrA PE=3 SV=1
-------HDTVLCFSSRGRVYWIKVYELPQGGRSARGRPMVNLEQGERITAMLPVREGYFVFMATSAGTVKKTPLRDFSRPLSRGI-----IAIDLHEDE
YLVGVAITD---GDQDLMLFTSAGKAVRFSEDQVRAMGAHGVRGVKLQPDQRVISLVVPEP-GTVLSVTENGYGKRTTVDQFPTKGRGTQGVIAIRTSER
NGQVGAVLVLPGDEIMLITEHGTLIRTSVDEIPVVGRDAQGVKLINLGDG--ERLAYVERVV--------------------------------------
------------
>tr|W9V4U8|W9V4U8_9GAMM DNA gyrase subunit A OS=Thiorhodococcus sp. AK35 GN=gyrA PE=3 SV=1
-------HDTVLCFSSRGRVYWLKVYEFPQAGRGARGRPMVNLEPNERINAMLPVRDGYYVFMATSAGTVKKTALKDFSRPLSRGI-----IAIDLRDDE
YLIGVAITD---GKQDLMLFTSAGKAVRFPEEQVRVMGAHGVRGVMLKEDQRVISLVVPEP-GTVLSVTEHGYGKRTRVEEFPTKGRGTQGVIGIGASER
NGQVGAVLVRPGDEIMLITEGGTLVRTCVDEIPTVGRSAQGVKLINLAEG--ERLVFVERIV--------------------------------------
------------
>tr|I3YAQ3|I3YAQ3_THIV6 DNA gyrase subunit A OS=Thiocystis violascens (strain ATCC 17096 / DSM 198 / 6111) GN=gyrA PE=3 SV=1
-------LDTVLCFSSRGRVYWLKVYELPHSGRGARGRPMVNLEPGERINALLPIREGLFVFMATSAGTVKKTPLTDFSRPLSRGI-----IAIDLREDE
VLVGVVITD---GKRDLMLFTSNGKAVRFSEDHVRVMGAHGVRGVRLQDGQRVISLLVPEP-GTVLSVTENGYGKRTRVEDFPTKGRGTQGVIGISTSER
NGQVGAVLVRPGDEIMLITEGGTLIRTTVDQIPVVGRSAQGVKLINLGDG--ERLVYVERIV--------------------------------------
------------
>tr|A0A0G1RCD5|A0A0G1RCD5_9BACT DNA topoisomerase (ATP-hydrolyzing) OS=Parcubacteria bacterium GW2011_GWA1_47_11 GN=UX77_C0024G0001 PE=4 SV=1
-------HDTILFFTSSGKAFRTKGYEVPESSRQSKGKAIVNFSQEENITAVVPLSKSGYLFMATTGGVVKKTDISEFENVRANGL-----IAIKLHPTD
SLRWVQATT---GKDEIIMTSSGGDAIRFKEKDVRPMGAAGVIGMRLDKGARIVSAEVIPADLKLLVVMKNGYGKRTELRHYKVQKRGGKGIKTAQITTK
TGIISAHVVDPNKEIIAASQKGVVIRTMLDSVSNLGRATQGVRIMRLDSG--DSIASVALV---------------------------------------
------------
>tr|A0A0G1G084|A0A0G1G084_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWC1_43_12 GN=gyrA PE=3 SV=1
-------HDNLLFFTTTGRVFQTKAYEIPEASRVARGQALVNFGPNEHVSSLVALKEENYLIMATKGGIIKKSPAEEFSNVRRSGL-----IAMNLTKGD
ELLWAKSTT---GSDELMLVSAKGQSIRFKEKDVRPMGAAGVHAIKLKNGDEVISMDVIRSKPMVLVVTENGFGKRTDLKQFKSQRRSGSGIKAAHVTPK
TGIVSARILNGEQDLIAISEKGQVIRTTLGSVSVLGRSTQGVRIMKMEAG--DKVASIACI---------------------------------------
------------
>tr|A0A0G1FVP0|A0A0G1FVP0_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWA2_43_9b GN=gyrA PE=3 SV=1
-------HDNLLFFTNTGRVFQTKAYEIPEASRVARGQAMVNFGPKEEVNALVAFKEENYLVMTTKDGIIKKTAIADFANVRRSGL-----IAIKLGKDD
FLRWVKPSS---GKDEIIMVTAKGQSVRFRESDARPMGAGGVRGLRLKKGDAVVGMDIIKATQELLVVMENGYGKKTELKQFKIQRRGGSGIKAAQVTAK
TGIVTAEILEDLEDIIAISKRGQVIRTSLGSISLLGRATQGVRIMKMDEG--DKIASVTCL---------------------------------------
------------
>tr|A0A0G1AMP7|A0A0G1AMP7_9BACT DNA gyrase subunit A OS=Parcubacteria bacterium GW2011_GWA2_42_11 GN=gyrA PE=3 SV=1
-------HDNLLFFTTTGRVFQIKGYEIPESSRVARGTAIVNFGPNEKVSALVATKEEKYLVMMTKDGIIKKTDIAEFTNVRRSGL-----IAINLNKGD
ELRWVRVSS---GQDEIILVTGGGQSIRFKEKDVRPMGAAGVRGLKLKKGDEVINLDVIKSKPELLVVMQNGYGKKTDLRQFKIQRRSGSGIKAAQVTAK
TGIVAAKILDPEQDLIAISQKGQVIRTALSSVSSLGRATQGVRIMKLEPG--DKVASVTCL---------------------------------------
------------
>tr|A0A0G0KKY8|A0A0G0KKY8_9BACT DNA gyrase subunit A OS=Parcubacteria (Magasanikbacteria) bacterium GW2011_GWA2_37_8 GN=gyrA PE=3 SV=1
-------HDNILFFTNRGRVFQLMAYDLPQGSRTAKGQALVNFAPNERVTALLSLADTKFLVMVTTKGVIKKTALEDFANVRRSGL-----IALKLKLDD
NLEWVKPTS---GVSDVMIATKKGIAIRFKESNVRQMGASGVRGIRLHANDEVIGMDVVDTSLEFFTIGENGVGKRTPLAEYKTQGRGGSGIKTANVTEK
TGIVQARVVDGDHDIVIMSTKGQVIRMPFKSIATSGRATQGTRLMRFKDG--DKVVSVTIL---------------------------------------
------------
>tr|F0S0B8|F0S0B8_DESTD DNA gyrase subunit A OS=Desulfurobacterium thermolithotrophum (strain DSM 11699 / BSA) GN=gyrA PE=3 SV=1
-------KDYLLIFTNQGKVYWLKAYEIPKTEKSTRGQSIRNFMSGEVVSRIIPVKDKKDIFFVTQRGYVKRTSLSEFSNPRSTGI-----NAINLEPGD
RLIYVGLVE---EKDNILLISKGGRAIRFHVQDVRQMGARGVKGMLLDEEDRIMAGTVVQPDVYLLIVMEKGYGKRVLLSEFPLQRRGGKGLIAAKLSEK
TGIADAITLKNEEPVIIVSRNGKIIRVNSSDVPVYSRYTRGVRIQKLSKE--DVVVSVSKVQ--------------------------------------
------------
>tr|A0A0F9RGQ3|A0A0F9RGQ3_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_0648450 PE=4 SV=1
-------HDTILFFTSKGRVYTMKCFEVPLQQRTAKGRPIINLREGEEISSMIPINNNDLLIMITKNGIAKKIQLKKFSKIPKSGL-----RAQSIRPND
MLVSVKMSN---ELQDIFIATKLGYAIRFDESELKEQRTMGYKGLSLREGDEVIEGLLVNIDDIILTLSQKGYGQRTFVKEYRKTRRAAKGVKNIKLTKI
TQKVIDVKISTEEDILVGTEQGQVIRVPIDSIRITHRPSKGVRVIKLYEN--DSVTSIGKCE--------------------------------------
------------
>tr|A0A0G1TLE3|A0A0G1TLE3_9BACT DNA topoisomerase (ATP-hydrolyzing) OS=Parcubacteria bacterium GW2011_GWA2_47_8 GN=UY09_C0009G0013 PE=4 SV=1
-------HDSVYIFNEEGVVFTLKAYDFPDKKRDQKGEYLMDYKAENFVAGAINVTGPAYLFMVTKRGIIKKVAFDQFTNVSKGGL-----IAMRLKEGD
HLMATMALY---QDEDILLVSKLGKAIHIQSGAVSALGAQGVRGMRLGSGDEVAGMIRITPKAHVLTMSVNGYGKRTEIRQFAIQNRGGKGLIASKVTAK
TGVRAVQLVTPYSDFMVITKQGKVLRGSLKQISTLGRATQGVRIIKLDEG--DELRSLNLMK--------------------------------------
------------
>tr|K2FNP0|K2FNP0_9BACT DNA gyrase subunit A OS=uncultured bacterium (gcode 4) GN=gyrA PE=3 SV=1
-------HDTILFFTNKGRVFGIKAWEIPESSRQAKGQALVNLEQGEEIRSILPMAKIKNLIMATKTGLIKKTKISEFENLRASGL-----IAIKLRNED
QLVSVHPTT---GEDHIILLTKGAKSIKFPEANVRPMGTTGVTGIRLDKEDELIGMEVFPAFRDILTIAEKGLGKRTPVHLFPVQKRAGKGVKAAVVTDK
TGLKTAIMVTQIDQVVITSRMGQVIKLPLKNIPQLGRATQGVILMRFAKA--DSVAAAAVLE--------------------------------------
------------
>tr|A0A0G0WQ70|A0A0G0WQ70_9BACT DNA gyrase subunit A OS=Microgenomates (Woesebacteria) bacterium GW2011_GWB1_41_10 GN=gyrA PE=3 SV=1
-------HDTILFFTNKGRVFGTKAWEIPESSRQAKGQALVNFDQGEEIKSILPLSKIKNLIMATKLGIIKKTNINEFENLRASGL-----IAIKLRGED
QLISVHPTS---GEDHIILLARGGKSIRFPEVNVRSMGTTGVAGIKLETQDELIGMDVFPGFRDILTIAEKGLGKRTPIHFFPIQKRAGKGVKAAVVNPK
TGLKTASMVTRIDQIIITSKMGQVIKLPLKNIPQLGRATQGVILMRFAKG--DSVAAAAVLE--------------------------------------
------------
>tr|A0A0G0X7C4|A0A0G0X7C4_9BACT DNA gyrase subunit A OS=Microgenomates (Woesebacteria) bacterium GW2011_GWA1_41_13b GN=gyrA PE=3 SV=1
-------HDTILFFTNKGRVFGLKAWEIPESSRQAKGQALVNLEQGEEIKSILPLSKIKNLVMATKNGLIKKTGIDEFENLRSSGL-----IAIKLRDND
MLISVHPTT---GDDHIILLTRNAKSIRFPETNARPMGTTGVTGIKMDTGDELIGMEVFPAYRDILTIAEHGLGKRTPIHLFPVQKRSGKGVKAAVVSAK
IGLKTAAMVTEYDQVIITSKMGQVIKLPLKNIPQLGRATQGVILMRFAKG--DSVAAAAVLE--------------------------------------
------------
>tr|A0A0G1G7T8|A0A0G1G7T8_9BACT DNA gyrase subunit A OS=Microgenomates bacterium GW2011_GWC1_43_13 GN=gyrA PE=3 SV=1
-------HDTILFFTNKGRVFGLKAWEIPESSRQAKGQALVNLEQEEEIRSILPLSKVKNLIMSTKRGLIKKTNLDEFENLRSSGL-----IAIKLRSDD
QLVSVHPTS---GSDHIIILTKGAKSIRFPELNVRPMGTTGVTGIKMEKDDEVIGMEVFPGFRDILTIAEKGLGKRTPIHLFPVQKRAGKGVKASVVNPK
TGLKTAIMVTQFDQVIITSKMGQVIKLPLKNIPQLGRATQGVILMRFAKA--DSVAAAAVLE--------------------------------------
------------
>tr|A0A0G0KMV8|A0A0G0KMV8_9BACT DNA gyrase subunit A OS=Microgenomates (Daviesbacteria) bacterium GW2011_GWF2_38_6 GN=gyrA PE=3 SV=1
-------HDYLLFFTNKGKIYWLKVHQIPEAARTAKGKAIVNLENEEKISAYVPVRNSHFIIMATKKGTVKKTSLDSFSNPRRTGI-----IAITLEDKD
ELINVELTD---GNQEIIIATKSGNAVRFNEKNVRGSGSQGVRGISLKGDDEVVGMIVASNEKTLFTVTENGYGKRTPIEDYRLINRGGSGVINIQCSER
NGVVAICDVDENDDIMLISKNGIVIRVPASDISVIGRNTQGVRIMKMEEG--DKAVSAVKVA--------------------------------------
------------
>tr|A0A0B3APB3|A0A0B3APB3_9ARCH DNA gyrase subunit A OS=archaeon GW2011_AR11 GN=gyrA PE=3 SV=1
-------HATLLCFTNRGRMHWLKTYAIPEASRQAKGKAIVNLEQGEHVTTFIPVREKHHLIMATRNGTIKKTNLIAYSNQRKTGI-----IAITLDEGD
RLMDVKLTD---GKQDVLLATAQGMAVRFAEEDVRPTGSQGVRGITLKRDDKVIGMIVAEKNKDILTITSNGYGKRTPIKLYRHISRGGSGVKDIQTEDR
NGVASVTCVSDNDEIMVITKSGITIRTPVSGISIIGRNTQGVRIMRLEQG--DEIVSVTRVE--------------------------------------
------------
>tr|A0A0J8UP47|A0A0J8UP47_9MYCO DNA gyrase subunit A OS=Mycobacterium heckeshornense GN=gyrA PE=3 SV=1
-------HDWILFFTSQGRVYRAKAYELPEAARTARGQHVANLQPEERIAQVIRIRSAPYLVLATRNGLVKKSRLTEFDSNRSGGI-----VAINLRDGD
ELVGAVLCS---ADDDLLLVSANGQSIRFSANALRPMGTSGVQGMRFNTDDRLLSLNVVR-DTYLLVATSGGYAKRTAIEEYPIQGRGGKGVLTIQYDPR
RGLVGALIVDDDTEVYAITSGGGVIRTAARQVRKAGRQTKGVRLMNLGEG--DTLVAIARNA--------------------------------------
------------
>tr|U5VMU9|U5VMU9_9ACTN DNA gyrase subunit A OS=Actinoplanes friuliensis DSM 7358 GN=gyrA PE=3 SV=1
-------HSWILFFTNKGRVYRAKAYELPEANRVAKGQHVANLLPDEHIAQVIQIPDEPYLVLATKNGLVKKTRLEEFDSNRSGGI-----IAINLREDD
ELVGATLAA---PENDLLLVSKKAQAIRFNATALRPMGTSGVIGMRFGEADELLAMEVVR-GLDVLVATNGGYAKRTPIEEYPVQGRGGKGVLTAKITER
RGLVGALVIDPEDELFAITSNGGVIRTPVKPVRRRDRNTMGVKLMDLPEG--VTIVALARNA--------------------------------------
------------
>tr|A0A010ZK08|A0A010ZK08_9ACTN DNA gyrase subunit A OS=Cryptosporangium arvum DSM 44712 GN=gyrA PE=3 SV=1
-------HDWILFFTNKGRVYRVKAYELPEASRTARGQHVANLQPDEQIAEVIEIRTAPHLVLATRNGLVKKTKLTEFDSNRQGGV-----IAINLREED
ELVGAELIN---ENDNLLLISKQAQAICFKADTLRPMGTSGVIGMRFSGEDELLSMHVAR-GMDVLVATEGGFAKRTPIEEYPVQGRGGKGVVTARIVTK
RGLIAALAVTTDDELFAITSNGGVIRTPVRQVRRRDRNTMGVKLMELPAG--VTLVAIARNE--------------------------------------
------------
>tr|D3PTX2|D3PTX2_STANL DNA gyrase subunit A OS=Stackebrandtia nassauensis (strain DSM 44728 / NRRL B-16338 / NBRC 102104 / LLR-40K-21) GN=gyrA PE=3 SV
-------HDWMLFFTNKGRVYRAKAYELPEASRTARGQHVANLQPDEQIAQVMQISGAPYLVLATRRGLVKKTKLTDFDSPRTGGV-----IGINLRDGD
EVVGAALIN---PDDDLLLVSKKAQAIRFMASSLRPMGTSGVIGMRFVEADELLTMEVVR-GMDILVATSGGYAKRTPVEEYPQQGRGGKGVLTAKITER
RGLVGALSVTPDDELFAITSEGGVIRTPVKPVRRTDRNTMGVKLMDLPEG--VSLLAMARSA--------------------------------------
------------
>tr|A0A0M2RLI3|A0A0M2RLI3_9ACTN DNA gyrase subunit A OS=Micromonospora sp. HK10 GN=gyrA PE=3 SV=1
-------HDWILFFTNKGRVYRAKAYELPEASRVAKGQHVANLQADEQIAQIIEIPNAPYLVLATKNGLVKKTRLEEFDSNRSGGI-----IAINLRDED
ELVGAALVG---PEDDLLLVSKNAQAIRFGATTLRPMGTSGVIGMRFSEEDVLLAMEVIHREKDVLVATNGGYAKRTPIEEYPVQGRGGKGVLTAKITER
RGLVGAVVISPDDELFAITSNGGVIRTPVKPVRRRDRNTMGVKLMDLPDG--VTIVAIARNA--------------------------------------
------------
>tr|A0A098BMN6|A0A098BMN6_9NOCA DNA gyrase subunit A OS=Rhodococcus ruber GN=gyrA PE=3 SV=1
-------HDWLLFFTTKGRVYRAKAYELPEANRTARGQHVANLQPDERIQGVIRLKSAPYLVLATRNGLVKKSRLSDFDSNRSGGI-----VAINLRGDD
ELVGAVLCS---SDDDLLLVSAKGQSIRFVASVLRPMGTSGVQGMRFNEDDALLSLNVVR-GTYLLVATSGGYAKRTPIEDYMAQGRGGKGVLTIQYDRK
RGLVGALIVDDDDELYAITSGGGVIRTPAKQVRKAGRQTKGVRLMNLGEG--DTLLAIARNA--------------------------------------
------------
>tr|Q8EVB9|Q8EVB9_MYCPE DNA topoisomerase (ATP-hydrolyzing) OS=Mycoplasma penetrans (strain HF-2) GN=MYPE6470 PE=4 SV=1
--DIVEERNGTCIVTRDNYIKFIDDVSIEEL-----DLSKAKIKDADIPVDIFRLSTLDHLVCLTNRGKMITIPAYKIKMTKLKDNGVHINELITIDSFE
KTILAFGVSKYSDNTEILVATKNSLIKRISLEDINLSKNKSSTYVSLKGGDDVVSAYILKKESEVVSVTQNGYATRYKIDEIPLVGRTAAGVKNMSLKDK
DLMAFTVPIPKHNFLFFISNRG-AKRIHINDIVVTSRSKLGKRIFQQID-SNPYINSGFMVGGRSNVFMLLESNELVSLKVAEIPITEA-----------
------------
>tr|G3J237|G3J237_9GAMM DNA topoisomerase 4 subunit A OS=Methylobacter tundripaludum SV96 GN=parC PE=3 SV=1
TTALITNEPLTVILSEKGWIRAAKGHDIDV--------ASLNYRSGDGFLDAVKCRTTQPVYILDSTGRAYSTATHDLPSART--QGEPLTGRLNPPPGS
LFLHLLAGQ---PDDWYVLASHFGYGFRVQLKELLSKNKAGKLLITLPDGAKVLKPTPIREADSLAVVTLQGRLLIFPVAELPALAK-GKGNKLIQIPTA
DYVIAAVALPENGQLKIIAGKRQLKGADVEHYS-AGRAKRGLALPRGFQ---------------------------------------------------
------------
>tr|D5BVT6|D5BVT6_NITHN DNA topoisomerase 4 subunit A OS=Nitrosococcus halophilus (strain Nc4) GN=parC PE=3 SV=1
EQALLPAEPITVVLSEKGWVRAAKSHEVDP--------TTLSYRTGDGYRASARGRSNQPAIFLDSTGRSYTLPAHGLPSARG--QGEPLSGHLQVVPGA
EFVAVLLAE---PEIFYLMASDAGYGFLCQAKHLYAKNRAGKAVLNLSAGARALPPVPVAEVEQIAIATNTGRLLLFPLGELPIMTR-GKGVKLIHIPSP
EAVRALAVVPPGGALQIFAGRRHLKSEDLEFYR-GERARRGHTLPRGFR---------------------------------------------------
------------
>tr|G4SX49|G4SX49_META2 DNA topoisomerase 4 subunit A OS=Methylomicrobium alcaliphilum (strain DSM 19304 / NCIMB 14124 / VKM B-2133 / 20Z) GN=parC PE=3
STELIANEPVTVILSQKGWIRAAKGHDIDV--------EGLNYRSGDGFLHAVKTRTTQPVYVLDSTGRVYTTASHDLPSARS--QGEPLTGRFNPPAGS
LFIGLLAGN---PEDWYVLAGSTGYGFRVQLKDLFGKNKAGKTVVTLPVGAKALLPVRVHDSDLLAIATLQGRLLIFPVNELPALTR-GKGNKLIQIPPS
DAVMALAVISEQSELKLISGKRTLKTADIGHYS-GARAKRGLHLPRGFQ---------------------------------------------------
------------
>tr|H8GMI3|H8GMI3_METAL DNA topoisomerase 4 subunit A OS=Methylomicrobium album BG8 GN=parC PE=3 SV=1
TTQLINNEPLTVILSQKGWIRAAKGHDFDV--------ESLNYRAGDSFLEAVKCRSTQPVYLLDSTGRAYGTTTHDLPSARS--QGEPLTGRLNPPPGA
LFAHLLAGD---PDDWYLVASSYGYGFRVQMKEFYSKNKAGKVLLTLSEGARVVKPVQLHEKDLLAVATLQGRLLIFPAQELPELVK-GKGNKLIQMPTE
DAVAAVAALPANGRLKITAGKRQLKEGDIAQYI-GSRAKRGLHLPRGFQ---------------------------------------------------
------------
>tr|A5CX99|A5CX99_VESOH DNA topoisomerase 4 subunit A OS=Vesicomyosocius okutanii subsp. Calyptogena okutanii (strain HA) GN=parC PE=3 SV=1
EDNLVLAEDVTVVLSNKGWVRRVKGHDIDP--------TTLNYKAGDSYLTSVKGKSNKMVIFIDSTGRSYSLLAHSLSNSRG--QGEPLTGKLSPPLGA
QFIDIIMGK---TSQNILLSSDVGYGFIATFDDLLSSRQTGKVFLSLSKGAQVMRVINVDDNQLVALATNRGRLLIFSISELPMLSK-GKGNKLIQIPVN
EFVASVCILFETQQLRVNAGKHYLKFQDLNNYI-SNRACRGKLLPKGYQ---------------------------------------------------
------------
>tr|A1AVX3|A1AVX3_RUTMC DNA topoisomerase 4 subunit A OS=Ruthia magnifica subsp. Calyptogena magnifica GN=parC PE=3 SV=1
EDDLAPAENITVVLSEKGWVRSAKGYSIDP--------NTLNYKAGDSYLTSVKGKSNKPVIFIDSTGRSYSLLANSLSSARG--QGEPLTGKLSPPSEA
RFVDVIMGK---ASQNILLASNIGYGFIATIGDLLSSRQAGKAFFSLSKGAQMMRIINVDDNQFIALVTNRGRLLIFPISELPILSK-GKGSKLIQISTK
EFVMNICILLETQHLKVIAGKRHFKFQDLSNYI-SSRARCGKLLPKGYQ---------------------------------------------------
------------
>tr|A0A0Q9P824|A0A0Q9P824_9GAMM DNA topoisomerase IV subunit A OS=Rhodanobacter sp. Soil772 GN=ASG75_00205 PE=4 SV=1
ESALVASEPVTVVLSQKGWARAAKGHDVDA--------EALNYREGDGLLAAVKARTTQQVAFIDSTGRAYSTLAHTLPSARG--NGEPLTGRFSPAAGA
SFDAVVAGD---NDTRLILATDFGYGFVTRFESLTGRNKAGKQIISLSDKAKVLAPQTSAARDRIVVVTTEGHLLMFSVAELPELDK-GKGNKLIEVPKA
ERVAGVAVVSEKGEVTLYAGQRKLRWADLVEYG-GNRATRGGLLPRGLR---------------------------------------------------
------------
>tr|A0A099CVX9|A0A099CVX9_9GAMM DNA topoisomerase 4 subunit A OS=Oleiagrimonas soli GN=parC PE=3 SV=1
ESDLVASEPVTVVLSQKGWVRAAKGHDVDA--------EGLNYREGDALSCAVPSRTNQQVAFVDSTGRSYSTLAHTLPSARG--NGEPLTGRFSPPAGA
RFDAMASGV---NDTRLVLASDFGYGFVTRFESMLSNKKAGKQLINLPDGAHVLPPPITASRDRIVVATTAGHLLMFSVAELPELDK-GKGNKLISIPKD
ERVAGVTVVAESGEVTLFAGQRKLKWSELVEYG-GNRATRGGLLPRGLR---------------------------------------------------
------------
>tr|I4WAW7|I4WAW7_9GAMM DNA topoisomerase 4 subunit A OS=Rhodanobacter sp. 115 GN=parC PE=3 SV=1
ESALVASEPVTVVLSQKGWIRAAKGHDVDA--------EGLSYREGDGLLAAVKARTTQQAVVIDSTGRSYSTPAHTLPSARG--NGEPLTGRFSPAAGA
SFDALVAGD---NDTKLILATDFGYGFVTRFEALTGRNKAGKQAINLPDGARILAPQITAARDRIVVVTSEGHLLMFSVAELPELDK-GKGNKLIEIPKA
ERVAGVAVVSEKGEVTMYAGARKLKWADLVEYG-GNRATRGGLLPRGLR---------------------------------------------------
------------
>tr|A0A0G9H8M8|A0A0G9H8M8_9GAMM DNA topoisomerase 4 subunit A OS=Luteibacter rhizovicinus DSM 16549 GN=parC PE=3 SV=1
ESALVASEPVTVVLSQKGWVRAGKGHDIDG--------EALSYRDGDSLLAISRARTTQQVAFIDSTGRAYATPAHTLPSARG--NGEPLTGRFSPPAGA
RFDAVVTAD---NDTRIVLATDFGYGFVTRFEALTGRQKAGKQIISLSDGARVLAPTISASRDRIVVVTGEGHLLMFSVAELPELDK-GKGNKLIEIPKA
ERVIGVAVVTEKGEITLYAGQRKLKWADLVEYG-GSRATRGGVLPRGLR---------------------------------------------------
------------
>tr|I1YHY7|I1YHY7_METFJ DNA topoisomerase 4 subunit A OS=Methylophaga frappieri (strain ATCC BAA-2434 / DSM 25690 / JAM7) GN=parC PE=3 SV=1
DTELLPTEPLTIVLSASGWVRAAKGHDVDP--------ESLNYRTGDRYLASVKARSNQQIVFLDETGRSYSLSAHTLPSARG--QGEPLSGRLQTGAEV
RFVAVLTAE---SEQKVLLSNSAGYGFITTFDNLLAKNKAGKTMFNLPDKAAMLPPILLPQDVHVAVASGDGRLLVFAADEIPALNK-GKGVRLINIPSA
EWLQSVTLIPENYSLTLYAGRRHLKPADLTHYS-GERGKRGHKLPRGLQ---------------------------------------------------
------------
>tr|M7P309|M7P309_9GAMM DNA topoisomerase 4 subunit A OS=Methylophaga lonarensis MPL GN=parC PE=3 SV=1
ETELLPTEAITVVLSESGWVRAAKGHDVDP--------GALNFRTGDRYLTSVKARSNQQIIFLDASGRSYSLPAHTLPSARG--QGEPLSGRLQSPPEM
RFVAVLTAE---LDKKVLLSNNAGYGFVTPMDNLLAKNKAGKAVFNLPDGAQMLPPMIIESEDQLAVASGDGRLLVFAMSEVPELNK-GKGVRLINIPQA
EWLQSLVRVPVDKGLTLHAGRRHLKPAELAHYA-GERGKRGHKLPRGLQ---------------------------------------------------
------------
>tr|F5T243|F5T243_9GAMM DNA topoisomerase 4 subunit A OS=Methylophaga aminisulfidivorans MP GN=parC PE=3 SV=1
ATELLPTEPLTIVLSESGWVRAAKGHDVDP--------ASLNFRTGDRYFASVKARSNQQIVFLDDTGRSYSLGAHTLPSARG--QGEPLSGRLQSPAEA
RFVAVMVVE---PEQSVLLTNTAGYGFITTLDNLLAKNKAGKAIFNIPKGAALLPPLFIDKETQIAVASGDGRLLVFPADDIPEMNK-GKGVRLINIPQA
EWMQAVVIVPNEQGLTLHAGRRHLKAADLAHYE-GSRGKRGHKLPRGLQ---------------------------------------------------
------------
>tr|A0A0F9SGU2|A0A0F9SGU2_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_0852750 PE=3 SV=1
ESELLPTEPLTIVLSESGWVRAAKGHDVDP--------TSLNFRTGDRYMSSVKARSNQQIIFLDSTGRSYSVLAHSLPSARG--QGEPLSGRFQTPSEA
RFVAVIAGD---LEATILLSNTAGYGFVTTLDNLLAKNKAGKTLFNLPKGAEVLPILWMDETDRLAVTTGDGRLLVFSANEMPLMNK-GKGVRLINIPQA
ESLYSVTLIPTERSLTIHAGKRHLKPTDLAHYA-GERGKRGSKLPRGLQ---------------------------------------------------
------------
>tr|C0N6L1|C0N6L1_9GAMM DNA topoisomerase 4 subunit A OS=Methylophaga thiooxydans DMS010 GN=parC PE=3 SV=1
ATELLPTEPLTIVLSESGWVKAAKGHDVDP--------TSLNFRTGDRYLTSVKARSNQQIVFLDETGRSYSLSAHTLPSARG--QGEPLSGRLQSAPEV
RFVSVLAVE---ADKTILLTNTAGYGFVTTLENLLAKNKAGKALFNLPKGAQILPPLLLEDNDQMAVASGDGRLLVFAASEIPTLNK-GKGVRLINIPQA
EWMQSVIIVPQQRSLTLHAGRRHLKPADLEHYA-GERGKRGHKLPRGLQ---------------------------------------------------
------------
>tr|A0A0R0B7P9|A0A0R0B7P9_STEMA DNA topoisomerase IV OS=Stenotrophomonas maltophilia GN=ARC23_15855 PE=4 SV=1
ETELVPSEPMTVVLSEKGWIRAAKGHDVDA--------SALSYRDGDALQGSVRARSTQQVAFLDSEGRAYSTPVHTLPSARG--NGEPLTGRFSPAPGT
SFVTLASAE---PDTRFVLASSHGYGFVTRFENLIGRNKAGKAMLNLSAGSSVLTPSVVAATDRIVAVTSSGNLLAIAANDLPELDK-GKGNKIIEIPKA
ERVVAIVAISPGQTLQVRSGQRTMKFNELDAYL-GARATRGHLLPRGWQ---------------------------------------------------
------------
>tr|C8KX43|C8KX43_9PAST DNA topoisomerase 4 subunit A OS=Actinobacillus minor 202 GN=parC PE=3 SV=1
ESDLTPTEDVTVILSEKGWVRCAKGHDIDV--------EGLSYRAGDGYLAHTRGRSNQPVVFLDSTGRTYALDPTSLPSARS--QGEPLTGKITLPEGA
TVEQVLMAA---PETKVLMASDSGYGFICTFEDLVSRNKAGKAVISLTENAKVLAPQLIDEDISLVAMSSAGRMLVFPLAELPILSK-GKGNKIINISAQ
ELLARLLLIKANQSLVFVSGKRKIKPSDIDNYR-GERARKGSQLVRGLS---------------------------------------------------
------------
>tr|A0A0B4XIL0|A0A0B4XIL0_9GAMM DNA topoisomerase 4 subunit A OS=Alcanivorax pacificus W11-5 GN=parC PE=3 SV=1
ETELMTADAITVVLSEKGWVRAAKGHDVDP--------TSLSYKTGDSFLSAALGKSNQPACFLDSTGRSYSLPSHTLPSARG--QGEPLSGRLSPPSGA
HFVAALMGQ---DKEAWLLATDAGYGFIARLGDLQANKKGGKTVLTVPKGSRVLHPQAVTEQALIAVLSNEGRLLVFPAKELPEMPR-GKGNKMMSIPSA
EFVQAVQVLSPEDTLTIHAGRRHLKSSDLEHYF-GERGRRGAKLPRGFQ---------------------------------------------------
------------
>tr|U7I1R2|U7I1R2_9GAMM DNA topoisomerase 4 subunit A OS=Alcanivorax sp. PN-3 GN=parC PE=3 SV=1
EADLLGSDPVTVVLSEKGWVRAAKGHDVDA--------EGLSYKSGDGFLAAAKGKSNQPVCFLDSTGRSYSLPAHTLPSARS--QGEPLSGRVNPPSGA
QFVAAIMGK---EKDAFLMSTDAGYGFVVRYGDLLANKKAGKTVLTVPKGAKVMAPKPMPEQALIAVVSNEGRLLVFPAADLPEMAR-GKGNKMVSIPSA
EFVQDIQVLGPEDALVVRSGKRHLKPADLEHYM-GERGRRGAKLPRGFQ---------------------------------------------------
------------
>tr|B4X456|B4X456_9GAMM DNA topoisomerase 4 subunit A OS=Alcanivorax sp. DG881 GN=parC PE=3 SV=1
ETDLLSADPVTVVLSEKGWVRAAKGHEVDV--------EGLSYKAGDKYKASAKGKSNQPVCFIDSTGRTYSLPAHTLPSARG--QGEPLSGRVSPPSGA
SFMAAVMGK---DKDAYLMSTDAGYGFVVRYADLLANKKAGKTVLNVPKGARVLSPQPIAADDRIALVSNEGRLLVFPVSELPEMVR-GKGNKMMSIPGA
EFVQDVQVVGPDDALTLYAGKRHLKAGDLEHYY-GERGRRGAKLPRGFQ---------------------------------------------------
------------
>tr|U7FPM5|U7FPM5_9GAMM DNA topoisomerase 4 subunit A OS=Alcanivorax sp. P2S70 GN=parC PE=3 SV=1
ETDLVSADPVTVVLSEKGWVRAAKGHDVDV--------EGLSYKAGDKYRASARGKSNQPVCFIDSTGRSYSLPAHTLPSARG--QGEPLSGRVSPPSGA
IFMAAVMGK---EKDAFLMSTDAGYGFVVRYTDLLANKKAGKAALSVPKGAKVLVPQAVGSDDLIALVSNEGRLLVFPVKELPEMAR-GKGNKMMSIPSA
EFVQDVQVLGPQDSLTIFAGKRHLKASDLEHYY-GERGRRGAKLPRGFQ---------------------------------------------------
------------
>tr|A0A023Y531|A0A023Y531_9GAMM DNA topoisomerase 4 subunit A OS=Stenotrophomonas rhizophila GN=parC PE=3 SV=1
ETELVPSEPMTVVLSEKGWIRAAKGHDMDP--------STLSYRDGDALLGSVRARSTQQVAFLDSEGRAYSTLIHTLPSARG--NGEPLTGRFSPAAGS
QFLTLASGE---NNTRFVLASTHGYGFVTRFENLTGRNKAGKAMLNLTSGSKVLTPAVVAETDRIVAVTSSGNLLAIAAGDLPELDK-GKGNKIIDIPKA
ERVVAVVSVGPGNTLLVRSGTRTMSFKDLETYL-GTRATRGHLLPRGWQ---------------------------------------------------
------------
>tr|A0A0R0D6Y3|A0A0R0D6Y3_9GAMM DNA topoisomerase IV subunit A OS=Stenotrophomonas ginsengisoli GN=ABB30_07820 PE=4 SV=1
ETELVPSEAMTVVLSEKGWIRAAKGHDIDA--------AGLSYRDGDKLQAAARARSNWQVAFLDNTGRSYSTPVHGLPSARG--NGEPLTGRFSPAAGT
RFVTATSAE---PSQHFLLLSSHGYGFITKFENLIGRNKAGKALLNLADGADVLAPAPVSDSDRLVAVTSSGNLLAIAATELPELDK-GKGNKLIEIPKA
ERVIAIAAVSPGQNLQVLCGARTMAYKDLETYL-GTRGTRGQLLPRGWQ---------------------------------------------------
------------
>tr|A0A0Q4QKW5|A0A0Q4QKW5_9GAMM DNA topoisomerase IV subunit A OS=Stenotrophomonas sp. Leaf70 GN=ASF01_00855 PE=4 SV=1
ETELVASEPVTVVLSEKGWVRAAKGHDVDA--------GGLSYREGDGLLAAVRGRSTQQVAFLDNEGRAYSTPTHTLPSARG--NGEPLTGRFSPAAGS
SFVTLASGD---NDTRFVLASSHGYGFVTRFENLTGRNKAGKAMLNLSTGAAVLQPMVVAQTDRIVAVTSAGNMLAIPATELPELDK-GKGNKIIEIPKA
ERVVAVVAVSPGATLQVRSGQRTMSFKELDAYV-GARASRGHLLPRGWQ---------------------------------------------------
------------
>tr|A0A0R0AT58|A0A0R0AT58_9GAMM DNA topoisomerase IV OS=Stenotrophomonas panacihumi GN=ARC20_02570 PE=4 SV=1
ETELVASEPMTVVLSEKGWIRAAKGHEVDP--------AGMSYRDGDGLLQAVRSRSTQQVAFLDTEGRSYSTLVHTLPSARG--NGEPLTGRFSPAAGA
SFQVMATGE---NDSRFVLASSHGYGFVTRFENLTGRNKAGKAMLNLTPGSQVLRPAAVADSDRIVAVTSAGNLLAIAAADLPELDK-GKGNKIIDIPKA
ERVVAVAAVSPGNTLLVRSGARTMSFKDLDAYV-GARATRGHLLPRGWQ---------------------------------------------------
------------
>tr|D4T563|D4T563_9XANT DNA topoisomerase 4 subunit A OS=Xanthomonas fuscans subsp. aurantifolii str. ICPB 10535 GN=parC PE=3 SV=1
ETEMVASEPMTVVLSQKGWVRAAKGHEVDP--------AGMSYRDGDGLLTAVRSRSTHQVAFLDSDGRAYSTAVHTLPSARG--NGEPLTGRFSPASCA
AFQVMASAD---NATRFVLASSHGYGFVTRFENLTGRNKAGKAMLNLTTGSHVLTPAQVSQTDRIVAVTSAGNLLAVPATDVPELDK-GKGNKIIEIPKA
ERVVAVVAVAPGNTLLVRSGARTMSFKDLDTYV-GARASRGSLLPRGWQ---------------------------------------------------
------------
>tr|A0A0A0M6X9|A0A0A0M6X9_9GAMM DNA topoisomerase 4 subunit A OS=Lysobacter defluvii IMMIB APB-9 = DSM 18482 GN=parC PE=3 SV=1
ETDLAPSEPMTVVLSRKGWVRAAKGHDIDA--------SALNYREGDALLASAPARSNQQVAFLDSTGRSYSTIVHSLPSARG--NGEPLTGRFSPAAGA
SFETLASGT---DEDRFVLASSHGYGFVTRFANLTSRNKAGKAMLSLTTGAEVLQPAPVAESDRIVVVTTAGHLLAFPVGELPELDK-GKGNKLINIPKA
ERVAAVAVVPEGASLQVKSGARTMAWKDLENYL-GARASRGGLLPRGWQ---------------------------------------------------
------------
>tr|A0A0Q9BHI9|A0A0Q9BHI9_9GAMM DNA topoisomerase IV subunit A OS=Lysobacter sp. Root916 GN=ASE35_17750 PE=4 SV=1
ETELVASEPMTVVLSEKGWVRAAKGHDIDA--------ATLSYRDGDGLLGSAKSRSTQQVAFLDSTGRAYSTVVHGLPSARG--NGEPLTGRFSPAAGA
SFQALASGD---NDSRFVLASSHGYGFVTRFENLTGRNKAGKAMLSLTPNAKVLQPAAVGEADRVVAVTNVGHLLAFPVSELPELDK-GKGNKIIDIPKA
ERVVAVAVVAPGTTLSVRSGTRTMSWKDLDAYV-GARATRGGLLPRGWQ---------------------------------------------------
------------
>tr|A0A0A0F557|A0A0A0F557_9GAMM DNA topoisomerase 4 subunit A OS=Lysobacter arseniciresistens ZS79 GN=parC PE=3 SV=1
ETDLAPSEPMTVVVSEKGWVRAAKGFDVDA--------AALSYREGDELQAYARARSNQQVAFLDSTGRSYSTIVHSLPSARG--NGEPLTGRFSPAPGA
SFQAVASGD---NDTRFVLASSHGYGFVTRFENLTSRNKAGKAMLSLTPNAKVVQPAQVGEQDRVVVATSAGHLLAFPVSELPELDK-GKGNKLIDIPKA
ERVVAVAVVAPGGTLSVKSGARTMPWKDLDGYV-GARATRGGLLPRGWQ---------------------------------------------------
------------
>tr|A0A0Q7PLL2|A0A0Q7PLL2_9GAMM DNA topoisomerase IV subunit A OS=Lysobacter sp. Root494 GN=ASD14_04860 PE=4 SV=1
ETELVASEPMTIVLSEKGWVRAAKGHDVDA--------AALSYREGDGLLGAVKGRSTQQVAFLDSTGRSYSTLAHTLPSARG--NGEPLTGRFSPVSGA
SFQALASGD---NDARFVLATSHGYGFVTRFENLTGRNKAGKAMLSLTPNAKVLQPAQVAEKDRVVAVTNVGHLLAFPVSELPELDK-GKGNKIIDIPKA
ERVVAVAVVPQGGTLVVKSGSRTMSFKDLEEYV-GARATRGGLLPRGWQ---------------------------------------------------
------------
>tr|A0A0Q8J3Z1|A0A0Q8J3Z1_9GAMM DNA topoisomerase IV subunit A OS=Lysobacter sp. Root690 GN=ASD86_13400 PE=4 SV=1
ETELVASEPMTVVISEKGWVRAAKGHEIDA--------ATLSYRDGDSLLGAARGRSTQQVAFLDSTGRSYSALIHSLPSARG--NGEPLTGRFAPVAGA
SFQTLAAGD---NDMRFVLASSHGYGFVTRFENLTGRNKAGKAMLSLTPNAKVLQPAQVGEQDRVVAVTNVGHLLAFPVNELPELDK-GKGNKIIDIPKA
ERVVAVAVVAPGTTLSIKSGARTMSFKELEPYL-GARATRGGLLPRGWQ---------------------------------------------------
------------
>tr|A0A0A0EYP4|A0A0A0EYP4_9GAMM DNA topoisomerase 4 subunit A OS=Lysobacter daejeonensis GH1-9 GN=parC PE=3 SV=1
ESELVPSEPMTVVLSEKGWVRAAKGHDIDA--------GGLSYREGDGLLGAAKARSTQQVAFLDSTGRAYSTVVHSLPSARG--NGEPLTGRFSPAAGA
SFQTLASGA---DDDRFVLASSHGYGFVTRFENLTGRNKAGKAMLSLTPGAKVLQPAAVGDQDRVVAVTNVGHLLAFPVAELPELDK-GKGNKLIDIPKA
ERVVAVAVVPAGGMLTVKSGARTMSWKDLEAYV-GARATRGGLLPRGWQ---------------------------------------------------
------------
>tr|A0A0C2L946|A0A0C2L946_9CYAN DNA topoisomerase (ATP-hydrolyzing) OS=Tolypothrix campylonemoides VB511288 GN=SD81_42955 PE=3 SV=1
ETELVASEPMTVVVSEKGWVRAAKGHDIDA--------ASLSYREGDALLAAVPARSTQQVAFLDSTGRAYSTLVHTLPSARG--NGEPLTGRFAPAPGA
SFQALASGD---DDTRFVLASSHGYGFVTRFENLTGRNKAGKAMLSLTPGAKVVQPAQVADADRVVVVTNVGHLLAFPVAEVPELDK-GKGNKLIEIPKA
ERVVAVAVVPPNGSLSVKSGARTMSWRDLDAYL-GARATRGGLLPRGWQ---------------------------------------------------
------------
>tr|A0A0P7GDF9|A0A0P7GDF9_9XANT DNA topoisomerase IV OS=Xanthomonas sp. Mitacek01 GN=AO715_08785 PE=4 SV=1
ESDLVPSEPVTIVISEKGWVRAAKGHDVDP--------AAMNYRDGDGMLAFARGRSTQQVVFLDSNGRSYSTVAHSLPSARG--NGEPLTGRFSPAAGA
SFQTVVAGE---SDARFVVASSHGYGFVTRFENLTGRQKAGKAMLSLSPGSTVLQPAAVREADRLVVVTSAGHLLAFPVAELPELDK-GKGNKIIEIPKA
EQVVAFAVVPPNASLLVRSGARTMSFKELDAYL-GARASRGGLLPRGWQ---------------------------------------------------
------------
>tr|A0A0A0EQ88|A0A0A0EQ88_9GAMM DNA topoisomerase 4 subunit A OS=Lysobacter concretionis Ko07 = DSM 16239 GN=parC PE=3 SV=1
ETDLAPSEPMTVVLSEMGWVRAAKGHDVDA--------AAMNYREGDELLVATRTRSNQQVAFLDSTGRSYSTVVHSLPSARG--NGEPLTVRFSPAPKT
SFQAIASGD---NDQRFVLASSHGYGFVTRFENLTSRNKAGKAMLSLTPNAHVLQPAAVSAQDRVVVATSAGHLLAFPVSELPELDK-GKGNKLIDIPRA
EHVVAVAVVAPGASLSVKSGARTMTWKDLEAYL-GGRATRGGLLPRGWQ---------------------------------------------------
------------
>tr|A0A0R0CPP1|A0A0R0CPP1_9GAMM DNA topoisomerase IV subunit A OS=Stenotrophomonas terrae GN=ABB27_09570 PE=4 SV=1
ETELVPSEPMTVVLSEKGWVRAAKGHDVDG--------STLNYRDGDSLLAVARTRSTQQVAFLDTEGRAYSTPVHTLPSARG--NGEPLTGRFSPAPGS
SFVTVASGD---NNTRFVLASTHGYGFVTRFENLTGRNKAGKAMLNLSTGSAVLTPSQVAETDRIVAVTSAGNMLAIPASELPELDK-GKGNKIIEIPKA
ERVVAVVAVGPSNTLQVRSGQRTMSFKDLETYL-GTRATRGHLLPRGWQ---------------------------------------------------
------------
>tr|S9ZTM7|S9ZTM7_MANHA DNA topoisomerase 4 subunit A OS=Mannheimia haemolytica D35 GN=parC PE=3 SV=1
ESDLTPTEDVTVILSEKGWVRCAKGHDIDV--------QALSYRAGDDYLAHARGRSNQPVVFLDSTGRAYALDPTSLPSARS--QGEPLTGKITLPEGA
TVQQVLMAN---SETKVLMASDSGYGFICTFEDLVSRNKAGKAVISLTENAKVLPPQLLEENLSLVAMSNVGRMLVFPVSELPALSK-GKGNKIINISAA
EYLARLLVIKPTNSLVFVSGKRKIKPSDIDNYR-GERARKGSQLVRGLS---------------------------------------------------
------------
>tr|A0A0J5P5A8|A0A0J5P5A8_9PAST DNA topoisomerase 4 subunit A OS=[Actinobacillus] muris GN=parC PE=3 SV=1
ESDLTPTEPITVILSEKGWVRCAKGHDIDV--------QALNYKAGDGYLAHAHGKSNQPVVFIDSTGRSYALDPQTLPSARS--QGEPITSKITLTDGA
SVQYVLMAE---DNQKVLMASDSGYGFICQFSDLVSRNKAGKAVISLPENAKVLPPQLIGPDTLLAAMSSVGRMLVFPIAELPSLSK-GKGNKIINISAA
ELLARLFIIRPTSSLVFVSGKRKIKPNDIEKYR-GERARKGAPLVRGLN---------------------------------------------------
------------
>tr|Q7VL92|Q7VL92_HAEDU DNA topoisomerase 4 subunit A OS=Haemophilus ducreyi (strain 35000HP / ATCC 700724) GN=parC PE=3 SV=1
ESDLTPTEDITVILSEKGWVRCAKGHDIDV--------QGLSYRAGDGYLAHTRGRSNQPVVFLDSTGRAYTIDPTTLPSARS--QGEPLTSKISLPEGA
SIQQVLMAN---PESKMLMASDAGYGFICTFNDLISRNKAGKAVISLPENAKILVPQWIEDELSIVAMSTINRMLVFPLTELPTLTK-GKGNKIMNIATQ
ELLARLLLIKSNQSLVFMAGKRKIKPADIDHYR-GERARKGTQLVRGLN---------------------------------------------------
------------
>tr|K1ZPC5|K1ZPC5_9BACT DNA topoisomerase (ATP-hydrolyzing) OS=uncultured bacterium (gcode 4) GN=ACD_69C00018G0002 PE=3 SV=1
EEEIIPTEAVTVVLSQQGWIRVAKGHDIDP--------LSLSYKAGDGFKQAALGRSNQLAVFIDSTGRTYSLYAHTLPSARG--QGEPLTSRLNLPKDA
TIEGVIIGE---PEQSVLLASDAGYGFVAKLEDLYTKNRSGKTTINPPKGSKVLSPKIVTETQYLAAITNIGKMLLFPVAYLPVLSR-GKGNKIIGIPLE
EYLLDLVLLNETDKLVLTSGKRSLKFADLEAYQ-GERGRRGNKLPQGLR---------------------------------------------------
------------
>tr|K2DTX4|K2DTX4_9BACT DNA topoisomerase (ATP-hydrolyzing) (Fragment) OS=uncultured bacterium (gcode 4) GN=ACD_21C00120G0001 PE=4 SV=1
EEEVIAAEPVTVVLSQQGWIRVAKGHEIDP--------LTLSYKSGDGFKQAVLGRSNQLAVFIDSNGRTYTLPAHKLPSARG--QGEPLTSRLTPEPGA
TFEGVLIGN---PEQLVLLASDAGYGFIAKLEDLYTKNRAGKATLNVPKNCKALTPRVVTDDQYLAAITNEGRMLLFPVASLPVLSR-GKGNKIIGIPSA
EYLIDLVVLNEMNKLVLTAGKRNLSFNDLAAYQ-GERGRRGNKLPRGLQ---------------------------------------------------
------------
>tr|H8L4W3|H8L4W3_FRAAD DNA topoisomerase 4 subunit A OS=Frateuria aurantia (strain ATCC 33424 / DSM 6220 / NBRC 3245 / NCIMB 13370) GN=parC PE=3 SV=1
ESALVPAEPVTVVLSQKGWIRAAKGHDIDP--------ASLNYRDGDDLQGAVRARTTQQVAFVDSTGRSYSTPVHGLPSARG--NGEPLTGRFSPAAGA
SFDTLIAAD---PDTRLVLVSNFGYGFVTRFETLTGRNKAGKHIITLNDGARILTPQISAASDRIVVATSEGHLLMFAVADLPELDK-GKGNKLIEIPKA
EYVVGAVVVPESGEVTLYAGQRKLRWADLMQYG-GNRATRGGLLPRGLR---------------------------------------------------
------------
>tr|A0A0K8QNU9|A0A0K8QNU9_9GAMM DNA topoisomerase 4 subunit A OS=Mizugakiibacter sediminis GN=parC PE=3 SV=1
ESALVASEPVTVVLSEKGWVRAAKGHDVDA--------PGLSYREGDAYLAAARGRTVQQAAFIDSTGRSYSTPAHSLPSARG--NGEPLTGRFSPPAGA
RFDAVAIGD---AETRLVLASDFGYGFVTKFDTLCGRNKAGKQVLNLDDDARVLAPAYVGARDRIVVATTDGHLLMFSVAELPELDKGGKGNKLIEIPKA
ARVAGIAVVAESGEVTLYAGQRKLKWADLVEYG-GNRATRGGLLPRGFR---------------------------------------------------
------------
>tr|B2I9H4|B2I9H4_XYLF2 DNA topoisomerase 4 subunit A OS=Xylella fastidiosa (strain M23) GN=parC PE=3 SV=1
ESELVASEPMTVVLSEKGWIRAAKGHDVDP--------SGMFYREGDRLLAAVRTRSTHQVSFLDSEGRAYSTLVHTLPSARG--NGEPLTGRFSPAPGA
SFQAMASAD---NDKLFVLASSHGYGFITRFENLTGRNKAGKAMIHLTPGAQVMGLAPLTQHDRIVAVTSAGNLLAIAASELPELDK-GKGNKLIDIPKT
ERLVAVIAVASSHTLLLYSGERTMSFKDLEAYL-DTRGSRGQLLPRGWH---------------------------------------------------
------------
>tr|Z9JFL2|Z9JFL2_XYLFS DNA topoisomerase 4 subunit A OS=Xylella fastidiosa PLS229 GN=parC PE=3 SV=1
ESELVASEPMTVVLSEKGWIRAAKGHEVDP--------SGMSYREGDCLLAAVRTRSTHHVSFLDSEGRAYSTLVHTLPSARG--NGEPLTGRFSPAPGV
SFQAMASAD---NNSLFVLASSHGYGFITRFENLTGRNKAGKALLNLTPGAQVLPLAALTQHDRIVAVTSAGHLLAIAAGELPELDK-GKGNKLIDIPKA
ERVVAVIAVASSHTLLICSGERTMSFKDLDTYL-DARANRGRLLPRGWQ---------------------------------------------------
------------
>tr|J5HTA0|J5HTA0_9PAST DNA topoisomerase 4 subunit A OS=Haemophilus sputorum HK 2154 GN=parC PE=3 SV=1
ESELTPTEDVTVILSEKGWVRCAKGHDIDV--------QALSYRAGDGYLAHVRGRSNQPVVFLDSTGRAYTLDANSLPSARS--QGEPITGKISLPEGA
TVQHVLMAN---MDAKILMASDSGYGFICQFEDLVSRNKAGKVVISLTENAQVLAPQYIEENISLVAMSNVGRMLVFPITELPTLSK-GKGNKIINISAA
ELLTRLLLIKPTSSLVFISGKRKIKPSDIDNYR-GERARKGSQLVRGLS---------------------------------------------------
------------
>tr|A0A0E3Z3I6|A0A0E3Z3I6_9GAMM DNA topoisomerase 4 subunit A OS=Pseudoxanthomonas suwonensis GN=parC PE=3 SV=1
EIELVPSEPMTVVLSEKGWIRAAKGHDVDA--------AGLSYRDGDGLLAAVRSRSTQQVAFLDSQGRSYSTVVHTLPSARG--NGEPLTGRFSPAQGA
SFQALASGD---NDTRFVLASSHGYGFVTRFENLTGRNKAGKAMLNLTPNARVLQPAAVAEADRIVAVTSAGHLLAIPATELPELDK-GKGNKLIDIPKA
ERVVAVAAVAPSQTLQVRSGQRTMSFRELEEYL-GARATRGGLLPRGWQ---------------------------------------------------
------------
>tr|A0A0A2WPM3|A0A0A2WPM3_9GAMM DNA topoisomerase 4 subunit A OS=Lysobacter dokdonensis DS-58 GN=parC PE=3 SV=1
ETELVPSEPMTVVISEKGWIRAAKGHDVDA--------ASLSYREGDGLLAAVRARSTQQVAFLDSTGRSYSTVVHTLPSARG--NGEPLTGRFAPAAGA
SFQAMASGD---DETRFVIASSHGYGFVTKFVNLTGRQKAGKAMLSLTPGAKVVQPALVGESDRVVAVTTAGHLLAFPVKDLPELDK-GKGNKIIEIPKA
ERVVAVAVVPPGGKLSVKSGARSMSFKELDDYV-GARASRGGLLPRGWQ---------------------------------------------------
------------
>tr|A0A0Q8F9D7|A0A0Q8F9D7_9GAMM DNA topoisomerase IV subunit A OS=Pseudoxanthomonas sp. Root65 GN=ASD77_00395 PE=4 SV=1
ETELVASEPMTVVLSAKGWIRAAKGHDVDA--------STLSYRDGDGLLGAVRSRSTQQVAFLDSEGRSYSTAVHTLPSARG--NGEPLTGRFSPAAGA
SFQALASGD---NDSRFVLASSHGYGFVTRFENLTGRQKAGKAMLNLTAGANVLQPAAVPDTDRIVAVTSAGHLLAFPVSELPELDK-GKGNKIIEIPKA
EHVVAIAAVSPGATLLVKSGQRTMSFKDLDAYV-GARATRGGLLPRGWQ---------------------------------------------------
------------
>tr|E6WR27|E6WR27_PSEUU DNA topoisomerase 4 subunit A OS=Pseudoxanthomonas suwonensis (strain 11-1) GN=parC PE=3 SV=1
ETELVPSEPVTVVLSQKGWVRAAKGHDVDA--------AGLSYREGDALLGAVRARSTWQVAFLDSHGRSYSTPAHSLPSARG--NGEPLTGRFSPASGA
SFLALASGE---NDTRFVLASSHGYGFVTRFENLTGRNKAGKALINLATGANVLQPAVVGETDRIVAVTSAGHLLAIPAAELPELDK-GKGNKLIDIPRA
ERVVAVAAVGPAQKLQVYSGQRTMSFKDLDTYL-GARATRGGLLPRGWQ---------------------------------------------------
------------
>tr|G7UPY0|G7UPY0_PSEUP DNA topoisomerase 4 subunit A OS=Pseudoxanthomonas spadix (strain BD-a59) GN=parC PE=3 SV=1
QTELLASEPMTVIMSEKGWVRAAKGHDIDI--------AKLGYREGDSPLAAVRTRSNHQVAFLDSTGRSYSTAVHTLPSARG--NGEPLTGRFSPAAGA
SFQALASGE---NETRLVLASSHGYGFVTRFENLTSRNKAGKAMLNLTPNARVLQPALLAASDRIVAVTSAGNLLAIAASDLPELDK-GKGNKIIDIPKA
ERVVAIAAISPGGTLHVHSGARTMSFKDLDLYT-GTRATRGALLPRGWQ---------------------------------------------------
------------
>tr|L7H9I5|L7H9I5_XANCT DNA topoisomerase 4 subunit A OS=Xanthomonas translucens DAR61454 GN=parC PE=3 SV=1
ETELVPSEPMTIVMSEKGWIRAAKGHDVDP--------AGLSYRDGDSLLAAVRGRSTQQVAFLDSEGRAYSTLAHSLPSARG--NGEPLTGRFSPASGA
SFQAMASGE---NDSRLVLASSHGYGFVTRFENLTSRNKAGKAMLNLTPNAKVLPPASVGQTDRIVAVTSAGHLLAFPIADLPELDK-GKGNKIIDIPKA
ERVVAIAAVAPGNTLLVKSGQRTMSFKDLDAYL-GVRASRGGLLPRGWQ---------------------------------------------------
------------
>tr|A0A0H1AF80|A0A0H1AF80_9GAMM DNA topoisomerase 4 subunit A OS=Luteimonas sp. FCS-9 GN=parC PE=3 SV=1
ETDLVPSEPVTIVVSEKGWVRAAKGHDVDP--------AGLSYREGDRLLAFARARSTQQVAFLDSNGRSYSTIAHSLPSARG--NGEPLTGRFSPAAGA
AFQTLAAGD---NDGRFVVASSHGYGFVTRFENLTGRNKAGKAMLSLSPGATVLQPAAVRQADRLVAVTSAGHLLVFPVAELPELDK-GKGNKIIEIPKA
EQVVALAVVSPGSALLVRSGARTMAFKELDAYL-GARASRGGLLPRGWQ---------------------------------------------------
------------
>tr|A0A0R0BLE2|A0A0R0BLE2_9GAMM DNA topoisomerase IV subunit A OS=Stenotrophomonas koreensis GN=ABB25_08145 PE=4 SV=1
ETELVASEPMTVVLSEKGWVRAAKGHDVDA--------AGLSYRDGDRLQAAARARSTWQVAFLDNTGRSYSTAVHTLPSARG--NGEPLTGRFSPAAGA
QFVTATSAE---AQQRFVLLTSHGYGFITRFENLIGRNKAGKAMLNLSPGAGVITPAPLGETDRIVAVTSSGNLLAIPATELPELDK-GKGNKLIEIPKA
ERVIAVAAVAPGQNLLVQCGARTMAFKDLETYL-GTRGTRGQLLPRGWQ---------------------------------------------------
------------
>tr|A0A0R0CRV2|A0A0R0CRV2_9GAMM DNA topoisomerase IV subunit A OS=Pseudoxanthomonas dokdonensis GN=ABB29_11305 PE=4 SV=1
ETELLSSEPMTVVVSEKGWVRAAKGHDVDA--------SSLSYREGDGLLAAVRSRSTQQVAFIDSNGRSYSTAVHTLPSARG--NGEPLTGRFSPAAGA
GFQALASGG---NDDRFVLASSHGYGFVTRFENLTGRQKAGKAMLNLTTNAKVLQPAAVAETDRIVAVTSAGHLLAFAISELPELDK-GKGNKIIEIPKA
ERVVAVAAVAPGSTLLVRSGQRTMSFKDLDTYL-GARASRGGLLPRGWQ---------------------------------------------------
------------
>tr|A0A091BKE7|A0A091BKE7_9GAMM DNA topoisomerase 4 subunit A OS=Arenimonas oryziterrae DSM 21050 = YC6267 GN=parC PE=3 SV=1
ENELVPSEPVTVVLSAKGWIRAAKGHEVDA--------ASLSYRDGDKLLQAVRGRSTQQVAFLDSSGRSYSSLAHTLPSARG--NGEPLSGRFSPPAGA
QFTGLAVGE---NDTRFLVSSSWGYGFVTRFENFTGRNKAGKQLINADDAADILAPALVTQTDWIVSITNSGHLLAFPITELPELDK-GKGNKLIQIPPA
EKVIAVASVRQGGELTLYCGQRKLGWRDLQAYE-GARASRGNALPRGFQ---------------------------------------------------
------------
>tr|A0A091B199|A0A091B199_9GAMM DNA topoisomerase 4 subunit A OS=Arenimonas malthae CC-JY-1 GN=parC PE=3 SV=1
ETELVPSEPVTVVLSKKGWIRSAKGHDVEA--------AALSYRDGDGLLQAARGRSTQQVAFVDSTGRSYSALAHSLPSARG--NGEPLSGRFSPPAGA
SFIGLAVAD---NDARYVLASSHGYGFVTRFENFTGRNKAGKQLINAGDGAELLAPVPVNKTDFIVSITSAGHLLAFPLAELPELDK-GKGNKLVQIPPA
EKVVAVASVKQGGELTIYSGRQKLSWRDLQAYE-GSRASRGNLLPRGFT---------------------------------------------------
------------
>tr|A0A091BAL1|A0A091BAL1_9GAMM DNA topoisomerase 4 subunit A OS=Arenimonas composti TR7-09 = DSM 18010 GN=parC PE=3 SV=1
ETELVPSEPVTVVLSKKGWARQAKGHEVDA--------AALSYRDGDGLLMAVRGRSTQQVGFLDSSGRAYSALAHTLPSARG--NGEPLSGRFAPPAGA
AFVGAAIGD---DEARFLLASSFGYGFVTRFANFVGQKKAGRQLINADADAALLPPAPVVKTDWIVAVTSAGHLLAFPITELPELDK-GKGNKLVQIPPA
EKVVAVASVRNGGELTVYSGRQKLAWRDLQAYE-GSRASRGNLLPRGFT---------------------------------------------------
------------
>tr|S6BBQ8|S6BBQ8_9GAMM DNA topoisomerase 4 subunit A OS=endosymbiont of unidentified scaly snail isolate Monju GN=parC PE=3 SV=1
ETELAPSEPVTVVLSEKGWVRAAKGHEIDP--------AGLNYKAGDAYLDSARVRSNQPVIFLDSTGRSYSLLAHTLPSARG--QGEPLTGRFSPPAGA
AFCAVIGGE---PERWWLLASDAGYGFRVQAKDLIANKKGGKAVLKLPEGARVLKPSPLHDTDRLVAVTSTGHMLVIPVAELPAMAR-GKGNKIIGIPSK
EYLVGVLVVPEGGRVRVLSGKRHLKAADLNAYE-GERGRRGNKLPRGFQ---------------------------------------------------
------------
>tr|V5DTQ6|V5DTQ6_9GAMM DNA topoisomerase 4 subunit A OS=Methyloglobulus morosus KoM1 GN=parC PE=3 SV=1
TTALIANEPLTVVLSEKGWIRAAKGHDFDV--------ESLSYRSGDGFLDAVKCRSTQPVYVLDSTGRVYSTTTHDLPSARS--QGEPLTGRLNPPAGS
LFKYLLAGN---PDDWVLLASSAGYGFRVRIEELFVKNKAGKALISLPDKSTVVRPASIAQGDLLAVATLQGRLLIFPVIDLPELAK-GKGNKIIQIPTK
DRVIAMATIPANGQLVIVSGKRQLKTNDIAHYS-GNRANRGLNLPKGFQ---------------------------------------------------
------------
>tr|W0TKH5|W0TKH5_9GAMM DNA topoisomerase 4 subunit A OS=Thiolapillus brandeum GN=parC PE=3 SV=1
ESELAPSEPVTVVLSEKGWVRAAKGHEIDP--------AGLNYKAGDGFCDAVRLRSNQPAIFLDSTGRSYSLMAHTLPSARG--QGEPLTGRFAPPDGA
VFRAALGGA---PEQRWLLASDAGYGFITQAGSLIANTRKGKSVLTLPKGARVLKARPVVHTDRVVAVTNEGRMLVIPLSDLPEMAR-GKGNKIIGIPGK
EYVVDMLVVPEGGKVRLISGKRHLKAADLNAYE-GERGRRGNKLPRGFQ---------------------------------------------------
------------
>tr|C8NBL7|C8NBL7_9GAMM DNA topoisomerase 4 subunit A OS=Cardiobacterium hominis ATCC 15826 GN=parC PE=3 SV=1
ETELTPSEAVTLILSKMGWIRGGKGHAIDG--------AALTYKNGDAYLTQISGRSNQQACLLADNGRSYTLALHGLPSARS--YGEPLSSSMSIDASA
HIIAAAIIE---PERRYLIAADNGYGFLIPGAELTSKTKSGKTLITPGGASRAITLQALPGETDILAISNEGRVALIPAEEIPELAK-GKGSQTLAIAKK
IRLAHILAVPRGRDITLHSGKQKLRANEREHYL-TPRGHKGNWLPKNYR---------------------------------------------------
------------
>tr|A0A0M1JFQ9|A0A0M1JFQ9_9GAMM DNA topoisomerase 4 subunit A OS=Achromatium sp. WMS2 GN=parC PE=3 SV=1
TPSVISSEPITVVLSSKGWIRAAKGHDIDP--------ESLSYKAGDEYLCMAKLRSQDQAILFDNTGRSYTLPVSNLPSARG--QGEPLTGRFTPPENA
NFISVLGGK---PEQWYLIASDAGYGFLLQQSDLIAKNKTGKIVLTLPKAAQALPPIPVSENSQIAAVTSAGRLLLFPLAELPRITK-GKGNKIIHIATP
LLMTVLAIIPYNCDLSLLVDSKHFKANDLDIYQ-GKRGQPGKLLPKGLQ---------------------------------------------------
------------
>tr|W2UGZ4|W2UGZ4_9GAMM DNA topoisomerase 4 subunit A OS=Gammaproteobacteria bacterium MOLA455 GN=parC PE=3 SV=1
EKDLLTAEPITVVLSDKGWIRGAKGHDIDP--------TTLSYKSGDKFLSAACGRSNQNVFLQDSVGRFYALAGHTLPSARG--QGEPATGRLNVSSGA
LFTDVIMGA---DDQKVLLGTDAGYGFIGKIGDLYTKNRAGKAVVSLPKGAKILSPKMVNANAQIAAVTNEGRLLVFPIAELPELAK-GKGNKIINIPGS
EFVIDYGVVSACDSLVVHSGKRYLKAKDLEHYS-GERGRRGHKLPRGFQ---------------------------------------------------
------------
>tr|W9T6V5|W9T6V5_9PSED DNA topoisomerase 4 subunit A OS=Pseudomonas sp. BAY1663 GN=parC PE=3 SV=1
ENELLPSEPVTVVISEKGWARCAKGHDIDA--------TGLSYKAGDGFKAAAAGRSNQYAVFIDSTGRSYSLAAHSLPSARG--QGEPLTGRLTPPPGA
GFECVLLPE---DEALYVIASDAGYGFVVKGEDLQAKNKAGKALLSLPSGARVVAPRPLADEDWLAAVTTEGRLLVFPVRDLPQLGK-GKGNKIIGIPGE
EYLVDLAVLPSGATLLLQAGKRTLRAEDLEHYK-GERGRRGNKLPRGFQ---------------------------------------------------
------------
>tr|A0A0F6RBW1|A0A0F6RBW1_9GAMM DNA topoisomerase 4 subunit A OS=Kangiella geojedonensis GN=parC PE=3 SV=1
ETDLIPTEPVTVVLSEKGWVRCAKGHDIDA--------AGMNYRSGDSFLDASQGKSNQYAVFLDSTGRSFSLLANTLPSARG--LGEPVTGRVNPIAGA
EFLATIMGE---DNDKLLFSSDAGYGFIAKFSDLVSKTKNGKAFLSLPSGAKVLKPKRIPGELYCVAISNEGRMLVFPLDDLPELAK-GKGNKIISIPTA
EFMVSVAVVASDDSLVIYSGKRHLKPKDLEHYR-GERGRRGSKLPRGFQ---------------------------------------------------
------------
>tr|A8PNH6|A8PNH6_9COXI DNA topoisomerase 4 subunit A OS=Rickettsiella grylli GN=parC PE=3 SV=1
KTEIISSEPMTVILSTRGWIRAAKGHDFDV--------SGLSFKAGDALKSTVLGRSNQLLVLMDSTGRSYSTPLHSLPSARS--SGEPLTSRFNPPPGV
QFESMISGN---PDQAIVVSSDAGYGFITQLSEMYSKNRNGKSLLKLSAHAHVLPLLALNDSSYVALATNTGYLLIISAYELPQLSR-GKGNKMMQISSK
EFIAKTSLPSKNSSLLLTSGKKQVKARDWIHYR-GKRGQRGRKLPRGLQ---------------------------------------------------
------------
>tr|Q48P20|Q48P20_PSE14 DNA topoisomerase 4 subunit A OS=Pseudomonas savastanoi pv. phaseolicola (strain 1448A / Race 6) GN=parC PE=3 SV=1
ENELMPTEPVTVVLSEKGWVRCAKGHDIDA--------TGLSYKAGDGFKTSSIGRSNQFAVFIDSTGRSYSVAAHTLPSARG--QGEPLTGKLQPPPGA
AFECVLMPE---DDALYVIASDAGYGFVVKGEDLQAKNKAGKALLSLPNGAKVILPRPVPEQNWLAAVTTEGRLLVFKISDLPQLGK-GKGNKIIGIPGE
EYVTDLAVIAQGATLVLQAGKRTLKPEDLEHYK-GERGRRGNKLPRGFQ---------------------------------------------------
------------
>tr|R4VPH3|R4VPH3_9GAMM DNA topoisomerase 4 subunit A OS=Spiribacter salinus M19-40 GN=parC PE=3 SV=1
ESDLIPSEPVTLVLSRKGWARAAKGHDVDP--------ERLSYRAGDGFADAAPGRSNQLAVFMDDHGRSYTLPAHTLPSARG--QGEPLTGRLQPPDGG
RFIHVLCGD---PDDRVLLASDMGYGFITQLGQLHGRQKAGKAVLNLSPGSRMLAPVTLSGVAQVAVATSAGRLLAFPLEQLPALAR-GKGNKLIDIPAA
ERVAGLCVLDADDPLVVQAGKRTLKADEFEGYV-GERGRRGRALPRGFQ---------------------------------------------------
------------
>tr|I1XH66|I1XH66_METNJ DNA topoisomerase 4 subunit A OS=Methylophaga nitratireducenticrescens (strain ATCC BAA-2433 / DSM 25689 / JAM1) GN=parC PE=3 S
ETELLPTEPLTIVLSASGWVRAAKGHDVDP--------GSLNYRTGDRYLASVKTRSNQQVVFLDESGRSYSLAAHTLPSARG--QGEPLSGRLQSAPEV
RFIAVIAAE---NDQMVLLSNTAGYGFVTRFDNLLAKNKAGKALFNLPEKAALLPPLVVDMPQQLAVAAGDGRLLVFPISEVPELNK-GKGVRLINIPQA
EWLQSVTLVPENHSLTLHAGRRHLKTADLQHYA-GERGKRGHKLPRGLQ---------------------------------------------------
------------
>tr|A4BSY5|A4BSY5_9GAMM DNA topoisomerase 4 subunit A OS=Nitrococcus mobilis Nb-231 GN=parC PE=3 SV=1
DTELVPSEPVTLVLSQRGWIRAAKGHDVDA--------QRLSYKAGDGYRDAAIGRTNQQAVFLDSQGRAYSLPAHTLPSARG--QGEPLTGRLSLPGGG
EFSYVLLGD---PDSLWLLASDHGYGFITRLGNLYSKNRAGKAVLSVAGGAQPLKPARIYAQDRLVAATTAGRLLVFPLQELPELGK-GKGNKLIQIPSP
EVVAGVLAVPPGRAVILQAGKRTLRPSDLERYL-GQRGRRGDALPRGFQ---------------------------------------------------
------------
>tr|U5T7R0|U5T7R0_9GAMM DNA topoisomerase 4 subunit A OS=Spiribacter sp. UAH-SP71 GN=parC PE=3 SV=1
ESELVPTEPVTVVLSRKGWARTAKGHDVDP--------EKLSYRASDGFAAAATGRSNQLAVFLDTHGRSYSLPAHSLPSARG--QGEPLTGRLQPPDGA
YFVHVLCAE---PEEGVLLASDSGYGFVTRVKSLQARQKAGKAIINRPADSEILAPIVLPAADRVAVATSAGRLLVFPLAQLPELSR-GKGNKLIDIPAA
EKVVGLCPLLADQSLVVGAGKRTLKSADLAAYE-GERGRRGRALPRGFQ---------------------------------------------------
------------
>tr|I2JIY0|I2JIY0_9GAMM DNA topoisomerase 4 subunit A OS=gamma proteobacterium BDW918 GN=parC PE=3 SV=1
EEDIVSAEPVTVVLSEMGWIRAGKGHDIDP--------VSLSYKSGDRYNLVARGRSNQPVIILDSTGRSYTVAAHTLPSARG--QGEPLTGRINPPSGV
SFTGMMMGG---DEGYYLLASDAGYGFIAKLAELQSKNKAGKAALTLPNGAKVLPPIAIATNSYVVAVTTEGRMLIFPAAELPVMPR-GKGNKMIGIPSA
EYVTAVTIFGERDVLKVISGKRHLKFAELEHYV-GERGRRGHKLPRGFQ---------------------------------------------------
------------
>tr|A0A0F7M5C8|A0A0F7M5C8_9GAMM DNA topoisomerase 4 subunit A OS=Spongiibacter sp. IMCC21906 GN=parC PE=3 SV=1
EEDVIAADPVTVVLSEMGWIRAAKGHDVDP--------VALNYKSGDRFKLATQGKSNQPVVVLDHTGRAYTVAAHSLPSARG--QGEPLTGRINAQSGA
HFEGLMMGA---ENSQFLLASDAGYGFVAKLADLQGKNKAGKAALTLPKGAKVLPPVPVTEDHYLAAVTTEGRMLVFPLADLPVMAR-GKGNKMIGIPSA
EYVIAAAVMGAQQSLKVIAGKRHLKLSELEHYL-GDRGRRGHKLPRGFQ---------------------------------------------------
------------
>tr|B3PDS9|B3PDS9_CELJU DNA topoisomerase 4 subunit A OS=Cellvibrio japonicus (strain Ueda107) GN=parC PE=3 SV=1
ETELMSVEPITVVISDKGWIRSAKGHDIDP--------TGLSYKAGDSFKFAVHGKSNQNVILLDSTGRSYAIPAHNLPSARG--QGEPLSGRINPPSGA
TFEGVLMGA---DDQRVLLASDAGYGFIAKLDDLASKNKSGKALLTLPDNAQVLPPQLINAQALLAAVSNDGRLLVFPVTELPELAR-GKGNKIMNIPSA
EFVVAVSVILPGQVLTLYSGKRTIKLGDLEHYK-GERGRRGNKLPRGFQ---------------------------------------------------
------------
>tr|C5BTN1|C5BTN1_TERTT DNA topoisomerase 4 subunit A OS=Teredinibacter turnerae (strain ATCC 39867 / T7901) GN=parC PE=3 SV=1
ETELISSEPVTVVLSEKGWIRSAKGHDIDP--------SALSYKAGDSFRVAARGKSSQATLLLDSTGRSYALPTHTLPSARG--QGEPVTGRLNPPSGA
VFEGLLMGD---DTQKVLLASDAGYGFIASLSDLYTKNRSGKAMLSVPAGGRVLAPQLLEDASWLAAFSNEGRLLAFPVSELPELAR-GKGNKIINIPAA
EFVVALVVFNEKSTIKVFSGKRHLKYKDLEHYL-GERGRRGNKLPRGFQ---------------------------------------------------
------------
>tr|Q21NR7|Q21NR7_SACD2 DNA topoisomerase 4 subunit A OS=Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) GN=parC PE=3 SV=1
EDQLLTSEPVTVVLSEKGWIRSAKGHEMDP--------ASLSYKAGDEFKFASRGKSNQSVILIDSTGRSYALAAHTLPSARG--QGEPVTGRLNPPSGA
TIEGMLMGS---EDQRVLLASDAGYGFVGKLGDLVSKNKAGKAALTLPKGAEVLPPTVIEDNTWLAAFSNEGRLLVFKVTELPELAR-GKGNKIINIPSA
EFVIALAVVQASDTLKVVSGKRHLKFKDLEHYI-GERGRRGNKLPRGFQ---------------------------------------------------
------------
>tr|B8KUQ1|B8KUQ1_9GAMM DNA topoisomerase 4 subunit A OS=Luminiphilus syltensis NOR5-1B GN=parC PE=3 SV=1
ETELASSDPLTIVLSEMGWIRAAKGHDIDP--------TSLNYKSGDGFKLAARGKSNLPTVVFDSTGRAYSIASHALPSARG--QGEPLTGRINPPSGA
TFEGLLTGA---DSDKFLLASDAGYGFVARFADLQSKNKAGKACLNLPKGARVLQPAAVPDQLLVAAVTSLGRLLVFPLSDLPEMAR-GKGNKIIGIPGP
EVVVGVCAMRSDDVLEVTAGKQHLKPADLEHYR-GERGRRGNKLPKGFQ---------------------------------------------------
------------
>tr|F3LI88|F3LI88_9GAMM DNA topoisomerase 4 subunit A OS=gamma proteobacterium IMCC1989 GN=parC PE=3 SV=1
EMDLLTSDPITVVLSEKGWIRSAKGHDVDP--------AALSYKAGDAYMFSAKGKTNQNALLIDSTGRSYALASHTLPSSRG--QGEPASGRLNPPSGA
VFTGLLMGV---EKQRVLIASDAGYGFVTELGNLYTKNKAGKALLTLPKGARVLPPFMIDADAYVAAASNEGRLLIFPLSDLPELAR-GKGNKMLSIPGA
EFVVSIAVIHSKQKLTVYSGKRHTKMADLEHYK-GERGRRGHKLPRGFQ---------------------------------------------------
------------
>tr|A0A0R2U988|A0A0R2U988_9GAMM DNA topoisomerase IV OS=SAR92 bacterium BACL26 MAG-121220-bin70 GN=ABS24_00490 PE=4 SV=1
EKDLLTAEPITVVLSDKGWIRAAKGHEIDP--------TSLSYKSGDKFLSAAFGRSNQNVFLQDSTGRYYSLAGHTLPSARG--QGEPATGRLNLPSGA
LFTDVIMGA---DDQKILMGTDAGYGFITKVGELFTKNKAGKAVVSVPKGGRILQPKMVGDDSYIVAVSNEGRMLVFAIGDIPELAR-GKGNKIINIPGS
EFVVDYALVGETDSLVVHSGKRYLKPKDLEHYR-GERGRRGHKLPRGFQ---------------------------------------------------
------------
>tr|K4KMN5|K4KMN5_SIMAS DNA topoisomerase 4 subunit A OS=Simiduia agarivorans (strain DSM 21679 / JCM 13881 / BCRC 17597 / SA1) GN=parC PE=3 SV=1
ETELMSADPITVVISDKGWIRAAKGHDIDP--------AALSYKSGDKYKLSVKGKSNQPVLLLDSTGRSYSLASHTLPSARG--QGEPITGSLNPPSGA
TFEGALMGA---DEDKVLLATDAGYGFVGKLGDMASKNRAGKALLTLPKGARVMVPTQVNGSDLLAAVSNEGRLLVFPLSELPELAR-GKGNKIMNIPSS
EYLLAVAVLKPADELTIYSGKRHLKPADLEHYR-GERGRRGNKLPRGFQ---------------------------------------------------
------------
>tr|A0A0F2P5D5|A0A0F2P5D5_9GAMM DNA topoisomerase 4 subunit A OS=Gammaproteobacteria bacterium BRH_c0 GN=parC PE=3 SV=1
EKDLITTEPVTVVLSDKGWIRAGKGHDLDP--------LSLSYKSGDQYLCAVKGRSNQDVVILDSSGRSYSLQSHTLPSARG--QGDPLTGLLSPPPGA
TFIGLLMGE---EKTPVLMATDAGYGFITRIGDLQGKNRAGKAAITVPNGGRVLPPTLIDDGALVVAVSNEGRMLVFPVGELPELTK-GKGNKIITIPTA
EFMLAVAVIVPGQQLLVHSGKRYLTLADLEHYR-GERGRRGNKLPRGFQ---------------------------------------------------
------------
>tr|U5V962|U5V962_9PSED DNA topoisomerase 4 subunit A OS=Pseudomonas sp. VLB120 GN=parC PE=3 SV=1
ENELMPTEPVTVVLSEKGWVRCAKGHDIDA--------TGLSYKAGDGFKAAAAGRSNQFAVLIDSTGRSYSLAAHTLPSARG--QGEPLTGRLTPPPGA
TFECVLLPD---DDALYVVASDAGYGFVVKGEDLQAKNKAGKGLLSLPNGAKVMTPRPVAEQDWLAAVTSEGRLLVFKVADLPQLAK-GKGNKIIGVPGD
EFVTDLAVIAEGATLVLQAGKRTLKPDDLEHYK-GERGRRGSKLPRGFQ---------------------------------------------------
------------
>tr|A0A089WPB7|A0A089WPB7_9PSED DNA topoisomerase 4 subunit A OS=Pseudomonas cremoricolorata GN=parC PE=3 SV=1
ENELMPAEPVTVVLSEKGWIRCAKGHDIDA--------TGLSYKAGDGFKAAAAGRSNQFAVLIDSTGRSYSLAAHSLPSARG--QGEPLTGRLTPPPGA
SFDCVLLPD---DEALYVVASDAGYGFVVKGEDLQAKNKAGKGLISLPNGSKVMAPRPVVANDWLAAVTTEGRLLVFRIADLPQLGK-GKGNKIIGVPGE
EYVTDIAVLGAGSTLVLHAGKRTLKADDLEHYK-GERGRRGSKLPRGFQ---------------------------------------------------
------------
>tr|M9YH82|M9YH82_AZOVI DNA topoisomerase 4 subunit A OS=Azotobacter vinelandii CA6 GN=parC PE=3 SV=1
ETELLPTEPVTVVLSEKGWVRCAKGHDIDP--------AALSYKSGDTFKAAAQGRSNQYAVFIDSSGRSYSLAAHSLPSARG--QGEPLTGRLAPPPGA
GFECVLLPD---DEALYVLASDAGYGFVAKGEDLQAKNKAGKALLSLPAGARVMAPRPLGGSDWLAAVTSEGRLLLFRVAELPQLAK-GKGNRIIAIPGA
EYLCDFVVLSERATLQLQAGKRTLKPADLEHYR-GERGGRGNKLPRGFQ---------------------------------------------------
------------
>tr|A0A0N0X232|A0A0N0X232_PSEAV DNA topoisomerase 4 subunit A OS=Pseudomonas amygdali pv. lachrymans GN=parC PE=3 SV=1
ESELMPSEPVTVVLSEKGWVRAGKGSDVDG--------STLSYKAGDTFKTSASGRSNQFAVFIDSTGRSFSLAAHTLASART--QGEPLSGKLTGQPGA
SYEWVVMPD---DEALYVLASDAGYGFLVKGEDLQAKNKNGKALINLSENSKVLMPLPVSDEQWIVALTSEGRLLMFKASELPQLGK-GKGNKIISVPSD
ELMTQLLVLDEGKSVVITSGKRTMKPGDLESYK-SMRGKRGSMLPRGYQ---------------------------------------------------
------------
>tr|A0A0F7K2I4|A0A0F7K2I4_9GAMM DNA topoisomerase 4 subunit A OS=Sedimenticola sp. SIP-G1 GN=parC PE=3 SV=1
ETDLTPSEPVTVVLSEKGWARTAKGHDIDP--------TSLSYKAGDRYLDSARLRSNQAAVFIDSTGRSYSVPAHTLPSARS--QGEPLTGRLAPASGA
TFSVVLGGD---PEQWYLVASDAGYGFLVQLKDLHAKNKAGKALLTLPKGARVLHPVAVTERDRVVAISNEGRMLTFPVSELPALSR-GKGNKIIGIPAK
EFVVAVACVPEDGKLIAHSGKRHIKLADLEHYQ-GERGRRGSKLPRGFQ---------------------------------------------------
------------
>tr|A0A0B2DE28|A0A0B2DE28_9GAMM DNA topoisomerase 4 subunit A OS=Serpens flexibilis GN=parC PE=3 SV=1
ETELLPSEPVTVVLSEMGWVRCAKGHEVDA--------AGLSYKAGDSFKSAAPGRSNQYAVFIDSTGRSYSLAAHSLPSARG--QGEPLTGRLTPPPGA
SFECVLLPD---DEALYVMASDAGYGFVAKGDDLQAKNKAGKALLTLPTGAKVLPPLPLSEQDWLAAATSDGRLLLFRIAELPQLPK-GKGNKLISIPAD
EYVTALAVLPEGANLVLQAGKRTLKGEDLAHYQ-GERGRRGNKLPRGFQ---------------------------------------------------
------------
>tr|A0A0Q4NKE6|A0A0Q4NKE6_9PSED DNA topoisomerase IV subunit A OS=Pseudomonas sp. Leaf58 GN=ASF02_10405 PE=4 SV=1
ETELMPSEPVTVVLSDKGWVRSAKGHDVDG--------AGMSYKAGDTFKMAANGRSNQSAVFIDSTGRSFSLPVNQMPSART--QGEPLSGKLSIQQGA
TFECVTLPD---DQAYYLLASDAGYGFVVKGEDLQSKNKNGKTLLTLPDNSKVIAPILLKDQDWVAAVTSEGRLLIFQASELPQLPK-GKGNKIISVPGD
EMMTQLVTLSEGDSLLITAGKRTMKPSDLEGYK-SSRGKRGSLLPKGYQ---------------------------------------------------
------------
>tr|L1M0G5|L1M0G5_PSEPU DNA topoisomerase 4 subunit A OS=Pseudomonas putida CSV86 GN=parC PE=3 SV=1
ENELMPTEPVTVVLSEKGWVRCAKGHDIDA--------TGLAYKAGDGFKVAAAGRSNQFAVFIDSTGRSYSLPAHKLPGARG--HGEPLTGHLKPPPGA
VFECVLMPD---DEALYVVASDAGYGFVVKGEDLQAKVTAGKALLSLPNGAKVLAPRPVSEQNWLAAVTTEGRLLVFKISDLPQLGK-GKGNKIIGIPGD
EYVTDMAVLSDGATLVLQAGKRTLKGEDLEHYK-GERGRRGNKLPRGFQ---------------------------------------------------
------------
>tr|A0Y8S6|A0Y8S6_9GAMM DNA topoisomerase 4 subunit A OS=marine gamma proteobacterium HTCC2143 GN=parC PE=3 SV=1
EEELMTTEPVTVVLSEKGWVRSAKGHDIDP--------QSLSYKSGDSFHLAAKGKSNQSVVILDSTGKAYTVAAHSLPSARG--QGEPLTGRINSPSGA
SFEGLMMGR---ADDLYLLASDAGYGFVVKFSDLQTKNKAGKAALSLPKGARVLQPGMVAELRYVAAVSNEGRMLIFPLTELPTMSR-GKGNKIIGIPPS
EFVVAVAIINERDTLRVHAGKRYVKFSELDHYM-GERGRRGHKLPRGFQ---------------------------------------------------
------------
>tr|F9UB07|F9UB07_9GAMM DNA topoisomerase 4 subunit A OS=Thiocapsa marina 5811 GN=parC PE=3 SV=1
EIDLAPSEPVTVVLSEKGWVRAAKGHEVDP--------AGLSYRSGDRFLMAVRVRSSQGVVFLDSTGRSYSLPAHSLPSARG--QGEPLTGRLDPPAGA
RFVAVLGEA---PECRVLMASDAGYGFIARMEDLFAKAKAGKAVLSLPKGAEVLVPLALSEGARLAAVTTAGHLLLFPVSELPEMPR-GKGNKIIGIPSA
ELVTALAVVPQGGSLVLLSGKRTLKPADLDVYQ-GERGRRGRLLPRGFQ---------------------------------------------------
------------
>tr|V4JQ42|V4JQ42_9GAMM DNA topoisomerase 4 subunit A OS=uncultured Thiohalocapsa sp. PB-PSB1 GN=parC PE=3 SV=1
ENELTPSEPITVVLSEKGWVRAAKGHDIEP--------EALSYKAGDRFLAAARLRSNQPVVFLDSTGRSYSIQANTLPSARG--QGEPLTGRLELPQGA
SFVAVVGDE---QPRRWLLACDAGYGFICQFNALLVKPKTGKAILSLPAGARVLPPVALPPLDRVAAVTSAGRLLVFPIVELPELNR-GKGNKIIGIPAA
EIMTAVALIPDAGQLTLHSGKRTFKPADLDRYQ-AERGRRGVLLPRGFQ---------------------------------------------------
------------
>tr|I3YH87|I3YH87_THIV6 DNA topoisomerase 4 subunit A OS=Thiocystis violascens (strain ATCC 17096 / DSM 198 / 6111) GN=parC PE=3 SV=1
ENELAPSEPVTVVLSEMGWIRAAKGHEVDV--------VGLSYRSGDRFLGAARIRSHQTVVFLDSTGRGYSLPANGLPSARG--QGEPLTGRLDPPPGA
RFVAVLGDL---PESRYVLASDAGYGFIARMEDLFAKPKAGKAIISLSPGANVLVPVPVPVGARLAATTSAGYLLVFPVSELPEMAR-GKGNKIIGIPTA
EVMVALAVVPAGGSLKILSGKREFKPADLEIYQ-GERGRRGRLLPRGFQ---------------------------------------------------
------------
>tr|A0A0K1X8S9|A0A0K1X8S9_9GAMM DNA topoisomerase 4 subunit A OS=Pseudomonadaceae bacterium E1148 GN=parC PE=3 SV=1
ESALVPVEALTIVLSEQGWVRAAKGHEVDA--------AALSYKAGDGLKQAQPARSNQQVSFLDSEGRSYSLAAHTLPSARG--QGEPLTGRLAPPMGA
SFEWILAAE---DEALYLMASDAGYGFLVKGADLHTKNKAGKALITLPTAAKVLPPMEVQESQLLAVVTNEGRLLVFALKELPILSR-GKGNKIIGITAE
EWVVGCALVTASDSLIVQSGKRTLKPDDLEHYY-GERGRRGSKLPRGFQ---------------------------------------------------
------------
>tr|A0A0K2WS45|A0A0K2WS45_9GAMM DNA topoisomerase 4 subunit A OS=Bathymodiolus azoricus thioautotrophic gill symbiont GN=parC PE=3 SV=1
EDDLVPAENVTVVLSDKGWVRSAKGHDIDP--------TTLNYKSGDNYLTSAKGRSNKVAVFLDSTGRSYALTANSLPSARG--QGEPLTGKLTPPADA
KFVDVVMGD---DSQNILLVSNAGYGFIATIGDLLSKKKAGKASLSLPGVAKVMKVIKVNEKQFVAATTNRGRLLIFPVSELPILSK-GKGNKLIQIPSK
EFVVSVCVLLDTQNLKVTAGKRHLKFQDLTNYM-GVRAKRGNLLPKGYQ---------------------------------------------------
------------
>tr|D2U2B5|D2U2B5_9ENTR DNA topoisomerase 4 subunit A OS=Arsenophonus nasoniae GN=parC PE=3 SV=1
EHDILPSEPVTIILSVMGWVRSAKGHDIDP--------TNLNYKAGDGFCSAARGKTNQPVVFLDSTGRSYSLDPLDLPSARG--QGEPLTGKLALPPGA
TIEHVLTAA---EEQKYLLASDAGYGFICTFSDLVAKNKAGKALITLPSNAKVLAPLEVNQQDLLLAITKAGRMLIFPVSELPQLSK-GKGNKIINISAA
DLLVWLMFLQPQSSITLYFGKRKLNPEDLQKYR-AERGRKGSSLPRGLQ---------------------------------------------------
------------
>tr|B8GTV5|B8GTV5_THISH DNA topoisomerase 4 subunit A OS=Thioalkalivibrio sulfidiphilus (strain HL-EbGR7) GN=parC PE=3 SV=1
ESELVPTEPLTVVLSKMGWVRAAKGHDVDA--------EGLSYKSGDAFLSAARGRSNQPAVFIDSTGRTYTLPAHTLPSARG--QGEPLSGRLSPPDGA
RFVGVMMGA---PSDLFLLSTDYGYGFVCSLEDMQSRNKAGKAVLSVPAGAKVLPPVRVRDADWIAAATSEGHLLVTRLNELPRMAR-GKGNKIINVPSA
EWVAAITLVQDGEPLTVVAGKKFKKGPEVDEYA-AERGKRGKKLPRGFQ---------------------------------------------------
------------
>tr|H1G2I8|H1G2I8_9GAMM DNA topoisomerase 4 subunit A OS=Ectothiorhodospira sp. PHS-1 GN=parC PE=3 SV=1
ESALIPSEPLTVVLSRMGWVRAAKGHEVDA--------AGLSYKSGDGFLSASPGRSNQQAVFIDSTGRTYALAAHTLPSARG--QGEPLSGRLSPPDGA
RFVGVMMGA---PDDLYLLATDHGYGFICTLEDMISRNRGGKVVLTVPEGANVLPPVRIRERQRLAAATSDGYLLVTVLSDLPRMAR-GKGDKIINIPSA
EWMVEPALVAEGEVLNVVAGKKFKKGAELEEYL-GERGRRGRKLPRGFQ---------------------------------------------------
------------
>tr|W0DKX3|W0DKX3_9GAMM DNA topoisomerase 4 subunit A OS=Thioalkalivibrio thiocyanoxidans ARh 4 GN=parC PE=3 SV=1
ETALVPTEPLTIVLSKMGWVRAAKGHEVDP--------AALNYKAGDGFLAALAGRSNQPVAFLDSTGRAYTLPAHTLPSARG--QGEPLSGRVTLADGG
HVVGLATGA---PDERWVLATDHGYGFVVRLGDLFGRQKAGKAVLNVPAGADVLAPQRLRDTDRIALATSDGHLLVIPATDLPEMAR-GKGNRIIGIPAA
ERVVAIAVLPAGATLVVHAGRRFKGPSEWAGYE-GERGRRGLKLPRGYQ---------------------------------------------------
------------
>tr|G4E7P5|G4E7P5_9GAMM DNA topoisomerase 4 subunit A OS=Thiorhodospira sibirica ATCC 700588 GN=parC PE=3 SV=1
NSALIPAEPVSVVLSSMGWVRVAKGHEVDP--------ALLNYKAGDGFLALAKGYANQYAIFLDSTGRSYTLPVNTLPTARG--HGEPLSGRLSLPDGA
RFSDVLMGA---EDAPWLLACDHGYGFLCRLADMQSRNKAGKALLSVPEQAQALPAVAVDHDQWVAILSSEGYLLLFDLYEVPQMAK-GKGNKLIHIPPA
AQVLALTTLGPADGLCIQMGAQRLSAAQLQAYR-GSRSQRGHKLPRGLR---------------------------------------------------
------------
>tr|F3L3G5|F3L3G5_9GAMM DNA topoisomerase 4 subunit A OS=gamma proteobacterium IMCC3088 GN=parC PE=3 SV=1
EKELMSTEPITVVLSEKGWIRAAKGHDIDP--------TSLSYKAGDNFNLAAAGRSNQSAILIDSTGRAYTLPTHNLPSARG--QGEPVTGRISPPPGV
GFKALLLGD---ERQKILLASDAGYGFVTELGHLMAKNKAGKAILNLPNGSEVLPPAQVPDDLLVAAVSTEGRLLVFPLADLPELAR-GKGNKILSVPSA
EMVKGIAVLTQESRLVLHAGKRHLKVSELDHYR-GERGRRGSKLPRGLQ---------------------------------------------------
------------
>tr|A0A095VS08|A0A095VS08_9GAMM DNA topoisomerase 4 subunit A OS=Pseudohaliea rubra DSM 19751 GN=parC PE=3 SV=1
ELELVSADPITVVLSEKGWIRAAKGHEIDP--------MTLSYKSGDGFKLAARGRSNQPAVLLDSTGRAYTVPTHNLPSARG--QGEPVTGRISPPSGA
VFNGLLMGD---GSQRYLLASDAGYGFIGRLGDLQAKNRAGKAVLTLPKGAEVLPPSPVADASWVAAVSSEGRLLVFPLEDLPALAR-GKGNKIIGIPSA
EFVVGVLALGDDDALVIHAGRRHLKAAELEHYR-GERGRRGNKLPRGFQ---------------------------------------------------
------------
>tr|H3NWY0|H3NWY0_9GAMM DNA topoisomerase 4 subunit A OS=gamma proteobacterium HIMB55 GN=parC PE=3 SV=1
ELELTSADPMTVVVSEKGWIRAAKGHDIDP--------ETLNYKSGDAFKFAALGRSNQTTVVFDSTGRAYSIPTHQLPSARG--QGEPLTGRIAPPSGA
TFEGLMTGT---EHQKFLLASDAGYGFVAKFGDLVAKNKAGKAVLSLPKGAQVMPPVIVPQNLLVAAATSEGRLLIYPLADLPELAK-GKGNKIIGIPSA
ELLVGLLVFGDEDILQVNSGRQHLRLSDLEHYR-GERGRRGNRLPKGFQ---------------------------------------------------
------------
>tr|B8KJU4|B8KJU4_9GAMM DNA topoisomerase 4 subunit A OS=gamma proteobacterium NOR5-3 GN=parC PE=3 SV=1
ELELMTADPITVVLSEKGWIRAAKGHDMDP--------ATLSYKSGDSFKLAARGRSNQPAVIIDSTGRAYTLATHNLPSARG--QGEPLTGRINPPSGA
GFDGLMMGD---NEQRCLLASDAGYGFVTTLAELQTKNRAGKAALSLPAGAKVVSPVPINGAQWVAAVSNEGRLLLFPLADLPSLSR-GKGNKIIAIPGP
EYVVATAVLKDDDGLTVWAGKRHLKRAELDHYR-GERGRRGNKLPRGFQ---------------------------------------------------
------------
>tr|B7S0V3|B7S0V3_9GAMM DNA topoisomerase 4 subunit A OS=marine gamma proteobacterium HTCC2148 GN=parC PE=3 SV=1
ELDLMTADPITVVMSEKGWIRAAKGHDIDP--------SSLSYKSGDGFKMAAKGRSNQPTVILDSTGRAYTVPSHNLPSARG--QGEPVTGRINPPSGA
TFEGLMMGD---EGDLYLLASDAGYGFVAKLGELQTKNKAGKGALNLPKGSGVMQPAAISEGAWVAAVTNEGRLLVFPLEDLPQMAR-GKGNKIIGIPTA
EFVIAVQVLTDKDTLVVYAGKRHHKFSDLKHYC-GERGRRGNKLPRGFQ---------------------------------------------------
------------
>tr|A0Z8F4|A0Z8F4_9GAMM DNA topoisomerase 4 subunit A OS=marine gamma proteobacterium HTCC2080 GN=parC PE=3 SV=1
ELELTTADPLTIVLSEKGWIRAAKGHDIDP--------EALSYKSGDGFKLAAKGRSNQPTVVFDSTGRSYSLPSHQLPSARG--QGEPLTGRINPPSGA
TFEALLTGV---DADRYLLASDAGYGFVGRFADLQTKNKAGKAVLSLPKGAGVLQPGSVGDTAMVAAVTNEGRLLVFPLTDLPELSR-GKGNKIIGIPTP
ELMVGAVVLVPGNVLQITAGKRHLKFSDLEHYR-GERGRRGNKLPNGFQ---------------------------------------------------
------------
>tr|A0A0D0KU13|A0A0D0KU13_9PSED DNA topoisomerase 4 subunit A OS=Pseudomonas fulva GN=parC PE=3 SV=1
EHDLLPNEKITVVLSEKGWVRSAKGHEIDA--------TGLSYKAGDGFKTAAPGRSNQYAVFIDSTGRSYSLAAHTLPSARG--QGEPLTGRLTPPPGA
SFECLLMPD---DEALYVIASDAGYGFVVKGEDLQAKNKAGKALLSLPNGALVVAPRPLAEEDWLAAVTTEGRLLLFKVADLPQLGK-GKGNKIIGIPGE
EYLTDLAVLAPGATLVLQAGKRTLKADDLEHYK-GERGRRGNKLPRGFQ---------------------------------------------------
------------
>tr|E2XKD1|E2XKD1_PSEFL DNA topoisomerase 4 subunit A OS=Pseudomonas fluorescens WH6 GN=parC PE=3 SV=1
ETELLPNEKITVVLSEKGWVRSAKGHDIDA--------TGLSYKAGDGFKTAAAGRSNQFAVFIDSTGRSYSVPAHTLPSARG--QGEPLTGRLTPPPGA
NFECVLLPD---DDSLYVIASDAGYGFVVKGEDLQAKNKAGKALLSLPNNAKVILPRPVDESNWLASVTTEGRLLVFKISDLPQLGK-GKGNKIIGIPGE
EYVTDIAVIPEGATLVLQAGKRTLRPDDLEHYK-GERGRRGNKLPRGFQ---------------------------------------------------
------------
>tr|A0A031FVJ4|A0A031FVJ4_9PSED DNA topoisomerase 4 subunit A OS=Pseudomonas sp. RIT288 GN=parC PE=3 SV=1
EHDLLPNEKVTVVLSEKGWIRSAKGHDIDA--------TGLSYKAGDGFKTSAAGRSNQSAVVIDSTGRSYSVAAHTLPSARG--QGEPLTGRLTPPPGA
TFECVLMPE---DDALYVIASDAGYGFVVKGEDLQAKNKAGKALLSLPNNAKVIAPRPVTENDLLAAVTSEGRMLVFNISDLPQLAK-GKGNKIIGVPGD
EFVTDIAVIPAGATLILQAGKRPYKAEDLEHYK-GERGRRGNKLPRGFQ---------------------------------------------------
------------
>tr|A0A085V9C8|A0A085V9C8_PSESX DNA topoisomerase 4 subunit A OS=Pseudomonas syringae GN=parC PE=3 SV=1
EHDLLPNEKVTVVLSEKGWVRSAKGHDIDA--------TGLSYKAGDGFQTAAMGRSNQYAVFIDSTGRSYSLAAHTLPSARG--QGEPLTGKLQPPPGA
TFECVLLPE---DDALYVIASDAGYGFVVKGEDLQAKNKAGKALLSLPKGAKVMLPRTVAEQNWLAAVTTEGRLLIFKISDLPQLSK-GKGNKIIGVPGD
EYVTDIAVIPQGATLVLQAGKRNLKPDDLEHYK-GERGRRGNKLPRGFQ---------------------------------------------------
------------
>tr|A0A0H3QRN2|A0A0H3QRN2_PSEAI DNA topoisomerase 4 subunit A OS=Pseudomonas aeruginosa str. Stone 130 GN=parC PE=3 SV=1
ETELMPTEPVTVVLSDKGWVRCAKGHDIDA--------AGLSYKAGDGFKAAAPGRSNQYAVFIDSTGRSYSLPAHSLPSARG--QGEPLSGRLTPPPGA
SFECVLLPD---DDALFVIASDAGYGFVVKGEDLQAKNKAGKALLSLPNGSAVVAPRPVREQDWLAAVTTEGRLLLFKVSDLPQLGK-GKGNKIIGIPGE
EYLTDLAVLPAGATLVLQAGKRTLKGDDLEHYK-GERGRRGNKLPRGFQ---------------------------------------------------
------------
>tr|K2AG51|K2AG51_9BACT DNA topoisomerase (ATP-hydrolyzing) OS=uncultured bacterium (gcode 4) GN=ACD_60C00025G0060 PE=3 SV=1
ETEMLPTEPMTVILSQMGWVRAAKGHDIDP--------ANLNYKAGDGFLSASLGKSNQPAVFLDSTGRAYAIPAHTLASARG--QGEPLTGRLNPPPNA
QFVAVILGE---SDQFYLLATDAGYGFVVKLEELYGKNKNGKAILSVPKGSKPLHPRLISETDLLAAATNTGHLLIFPLKELPELSK-GKGNKILSIPGS
EFILDIVTLSENQLLIVNAGNKQLKPIDWEHYK-GERGRRGLKLPKALQ---------------------------------------------------
------------
>tr|C7R6I9|C7R6I9_KANKD DNA topoisomerase 4 subunit A OS=Kangiella koreensis (strain DSM 16069 / KCTC 12182 / SW-125) GN=parC PE=3 SV=1
ETELLPTEPVTVILSEKGWVRCAKGHDVDA--------VGMNYRSGDKYLDSAQGKSNQYAVFLDSTGRTFSLLANTLPSARG--LGEPVTGRVNPIAGA
EFMATMMGE---DDDKFLFATDAGYGFVAKFSDLVTKTRNGKAFLNLPSGSKVVKPCSVKASQFCVAVSNEGRMLVFPLADLPELAK-GKGNKIISIPTA
EFMIAVTAIGEDDSLVIHSGKRHLKPKDLEHYR-GERGRRGHKLPRGFQ---------------------------------------------------
------------
>tr|K2AEY1|K2AEY1_9BACT DNA topoisomerase (ATP-hydrolyzing) OS=uncultured bacterium (gcode 4) GN=ACD_60C00054G0002 PE=3 SV=1
ETEMLPTESVTVILSQMGWIRAAKGHDIDL--------QNVSYKAGDTFLSEAKGKSNQPTLLLDSTGRIYSLPTHTLPSVRG--QGEPLTGRLSPPPNA
QFVAVIVGD---SEQKFLIASDAGYGFIVKTEELYSKNKNGKALLNLPKGSKPLQPRSINETDLLAAATNTGHLLIFPLKELPELAK-GKGNKIVSIPGS
EFLVDIAVLTESQLLIITAGNKQLKPTDWQHYV-GERGRRGLKLPRAMQ---------------------------------------------------
------------
>tr|N2J0I1|N2J0I1_9PSED DNA topoisomerase 4 subunit A OS=Pseudomonas sp. HPB0071 GN=parC PE=3 SV=1
ETELMPTEPVTVVLSEKGWVRSAKGHDIDA--------TGLSYKAGDGFKAAAPGRSNQFAVFIDSTGRSYSLAAHSLPSARG--QGEPLTGRLTPPPGA
TFETVLLPD---DGQLYVMASDAGYGFVVKGEDLQAKNKAGKALINLPAGAQVMVPKVVREQDLLAAVTTEGRLLVFNVSDLPQLAK-GKGNKIIGIPGD
EYMVGFAIVPPGGQLVLQAGKRTLKGDDLEHYR-GERGRRGNKLPRGFQ---------------------------------------------------
------------
>tr|A0A0D7F8T1|A0A0D7F8T1_9PSED DNA topoisomerase 4 subunit A OS=Pseudomonas oryzihabitans GN=parC PE=3 SV=1
ETELMPTEPVTVVLSEKGWVRQAKGHDVDP--------TGLSYKAGDGFKAAALGRSNQFAVFIDSTGRSYSVAAHSLPSARG--QGEPLTGRLTPPPGA
SFECLLLPD---DSGLYVMASDAGYGFVVKGEDLQAKNKAGKALISLPNGAKVLPPKPVAEDTSLAVVTNEGRLLVFAISELPQLAK-GKGNKLISIPGE
EYVVDLAVVPAGASLTLQAGKRPYKGSDLEHYR-AERGRRGNKLPRGFQ---------------------------------------------------
------------
>tr|E1VHZ0|E1VHZ0_9GAMM DNA topoisomerase 4 subunit A OS=gamma proteobacterium HdN1 GN=parC PE=3 SV=1
ETELVGAEPVTVILSQKGWVRAAKGHDIDA--------AGLSYKTGDALLGIAQGKSNQTVIFIDSTGRSYTLPAHGLPSARG--QGEPLIGKLTPPPGA
SFEALLMGA---DHDRYLLASDAGYGFVMKLSDAETRNKAGKALLSVPENAKVLAPRKVSDREYVAAVANDGRLLVFPLKELPELAR-GKGNQMMGIPSA
EYLVDVLLMTEADQLLICSGKRQLKFSDLQHYL-GERGRRGNKLPRGFQ---------------------------------------------------
------------
>tr|A0A0M9EAP1|A0A0M9EAP1_9DELT DNA topoisomerase 4 subunit A OS=Candidatus Magnetomorum sp. HK-1 GN=parC PE=3 SV=1
HVDILPAEPVTVVLSERGWIRSAKGHEMDP--------ENLNYKSGDRFFEAARGKSNQQVVFLDSTGRSYSLLAHGLPSARG--HGEPLSGRLNLPQKA
HFLTVLMDE---PNRKLLIASNAGYGFIAELSDLFTKNKAGKAILSLPKGSLPMHPIVVSEDSLLAAISNEGRMLVFPVNNLPKLSK-GKGNKIIGIPAA
EYLSFLIVFGPEANLVIHAGKRHFKHGNLALFM-GERGRRGKMLPRGFQ---------------------------------------------------
------------
>tr|L8MLZ0|L8MLZ0_PSEPS DNA topoisomerase 4 subunit A OS=Pseudomonas pseudoalcaligenes KF707 GN=parC PE=3 SV=1
ETELMPTEPVTVVLSEKGWVRCAKGHDIDA--------SGLSYKAGDGFKAASPGRSNQYAVFIDSTGRSYSLAAHSLPSARG--QGEPLTGRLTPPPGA
NFECVLLPD---DEALYVIASDAGYGFVVKGADLQAKNKAGKALLSLPSGSRVLAPRPLQENDCLAAVTTEGRLLVFKVADLPQLAK-GKGNKIIGVPGD
EYVTDLAVLPAGATLVLQAGKRTLRADDLEHYK-GERGRRGNKLPRGFQ---------------------------------------------------
------------
>tr|I3I6G9|I3I6G9_9GAMM DNA topoisomerase 4 subunit A OS=Cellvibrio sp. BR GN=parC PE=3 SV=1
ETELLSVDPVTVVISDKGWIRAAKGHDIDP--------TGLSYKAGDSFKFAVQGKSNQQVILIDSTGRSYSVPAHNLPSARG--QGEPLSGRISPPSGA
TFEGALMGA---DSQRVLIASDAGYGFVAKLEDLTSKNKAGKALLTLPEGAQVLPPQLINEQVQLAAVSNDGRLLVFPVTELPELAK-GKGNKIMNIPSA
EFVVALAVIHPGQLLTLHSGKRFIKAADLEHYK-GERGRRGNKLPRGFQ---------------------------------------------------
------------
>tr|A0A066RXL0|A0A066RXL0_9GAMM DNA topoisomerase 4 subunit A OS=Photobacterium halotolerans GN=parC PE=3 SV=1
ERDLLPSEAITVVLSDKGWVRHAKGHEVDP--------STLNYKSGDSYLSHARGKSNQPAVFIGSDGRSYALESHSLPSARS--QGEPITGRLNITAGS
SVRQVLMPD---DEQYWLMASDAGYGFVCKGSDMISKNRNGKALLSVPAECEVMPPQPISKSDQVLAITNEGRMLVFPLQDLPQLGK-GKGNKIINIPAA
EFLSHLLVLPAGSELTLYAGKRKLKTADLENFI-GERGRRGAMLPRGLQ---------------------------------------------------
------------
>tr|F9ZVN0|F9ZVN0_METMM DNA topoisomerase 4 subunit A OS=Methylomonas methanica (strain MC09) GN=parC PE=3 SV=1
TTELIANEPVTVILSQKGWIRAAKGYDIEV--------ETLNYRAGDGYLSSAKARTTQPAYVLDSTGRVYTITTHDLPSARS--QGEPLTGRLNPPPGS
LFTDVFSGQ---PDDWVLMASNAGYGFRVQLKELYSKNKAGKAVLSLPGGATVITPTPIPAADLLAVATLQGRLLIFPAQDLPELAK-GKGNKLIQIPAG
DAVAAVTALPVGGELKILSGKRHVKGVDIEQYS-GNRANRGTALPRGFQ---------------------------------------------------
------------
>tr|G2FHB5|G2FHB5_9GAMM DNA topoisomerase 4 subunit A OS=endosymbiont of Tevnia jerichonana (vent Tica) GN=parC PE=3 SV=1
ETDLSPSEPVTVVLSEKGWVRAAKGHEIDP--------AGLSYKAGDHYLAAAQLRSNQAAVFLDSSGRSYALPAHTLPSARS--QGEPLTGRLAPPVGT
SFCAVLGGD---AKQWYLLASDAGYGFRVQLEVMQSKNKAGKVLLTLPKGAKVLPPLPVHDGERVVAITNEGRMLVFPLAELPELNR-GKGNKIIGIPPK
EFVIALAVVPAGSALTAYAGKRHIKSSDLDSYQ-GERGRRGNKLPRGFQ---------------------------------------------------
------------
>tr|A0A0G3GAP5|A0A0G3GAP5_9GAMM DNA topoisomerase 4 subunit A OS=Thioalkalivibrio versutus GN=parC PE=3 SV=1
ESALVPTEPLTIVLSEKGWARAAKGHDVDP--------RGLSYKAGDAFQAAVIGRSNQPVAFIDSTGRTYTIAAHTLPSARG--QGEPLSGRVNPPEGA
RFVGLATGA---EEDRWLLGSDHGYGFIAKLGDLLGRQKAGKNVLSVPAGAAVLQPAPVRHEDHIAVVTTRGYLLVFPAAGLPELAR-GKGNKLIGIPSA
ERVLGVAVLAPQDTLVVHAGKRFKAPAEWAEYV-GERARRGRQLPRGYQ---------------------------------------------------
------------
>tr|A0A078KWQ3|A0A078KWQ3_9GAMM DNA topoisomerase 4 subunit A OS=Legionella massiliensis GN=parC PE=3 SV=1
EEDILPNEPITVVLSQKGWIRAAKGYDIDG--------RELSYKAGDEFKAQTNARSNQQVVFFDSEGKVYALPGHVLPSARG--QGEPLTGKLNPADGM
SFQALISGD---ANDWVLLASDAGYGFITRVEELYVKNRNGKACIKLSKNSVVLPPRLISESQLIAAVTSAGRLLIFPVAELPELSR-GKGNKIVNIPTA
EFVIDIQVLAHDDSLTVHAGKRHFKAADLNHYL-GERGRRGNRLPRGLQ---------------------------------------------------
------------
>tr|A0A0J6GFK4|A0A0J6GFK4_PSETA DNA topoisomerase 4 subunit A OS=Pseudomonas taetrolens GN=parC PE=3 SV=1
ENELVPTEPVTVVLSEKGWVRCGKGHDLDA--------TGLSYKAGDGYKTAAAGRSNQFAVFIDSTGRSYSVAAHTLPSARG--QGEPLTGRLTPPPGA
TFECVLLPE---DDALYVIASDAGYGFVVKGEDLQAKNKAGKALLSLPKGAQVMQPRPVSEQNWLAAVTTEGRLLIFKVSDLPQLGK-GKGNKIIGIPGD
EYVTDIAVLPEAATLVLQAGKRTLKADDLEHYK-GERGRRGNKLPRGFQ---------------------------------------------------
------------
>tr|C0QET9|C0QET9_DESAH DNA topoisomerase 4 subunit A OS=Desulfobacterium autotrophicum (strain ATCC 43914 / DSM 3382 / HRM2) GN=parC PE=3 SV=1
EEEVIQIEPMTVILSKNGWARTAKGHDIDI--------EKLKFKFGDDLLVTAPTMSNRPAVFFDSSGRSYSIATHTLASART--MGEPLTGRLTLKPEN
HIISLVTGE---DDDLFLLYTNTGFGFITRFSNLIAKSRTGKAVLTVEEFSEFMAPEPLKETDLLAAVTTSGRLIIFPVREMPIMEK-GKGNKIIGIPKN
TERIKLKLLPEGAAIVIYAGKHFLSVGNQDNYR-SKRGYRGKKLPRGFQ---------------------------------------------------
------------
>tr|A0A0M1JJZ2|A0A0M1JJZ2_9GAMM DNA topoisomerase 4 subunit A OS=Achromatium sp. WMS3 GN=parC PE=3 SV=1
SEPVTTVDLLTVILSEKGWIRAAKGHEIDP--------NSLNYKTGDSYLSSVRIRSNDQVILFDSLGRSYTLPAYILPSARG--HGEPVTKYLMPPAGA
TFLTILGGD---LQQWYLLASDAGYGLVLTLKDLLTKTKTGKAVLILSPNAQPMLPIAIHEQDQVAVITNTGRMLIFPVSKLPKLTR-GKGHSMIHIPAQ
ELLVAQTVLPPNTVLTLVAGSQSLKSKDLKLYQ-GTRGHRGAKLPKVWQ---------------------------------------------------
------------
>tr|K0NFD1|K0NFD1_DESTT DNA topoisomerase 4 subunit A OS=Desulfobacula toluolica (strain DSM 7467 / Tol2) GN=parC PE=3 SV=1
VTDLMDIEPVTIILSKNGWIRSAKGHEINP--------ETVKFKSGDSLMDCLRTRSDKPIIFLDNTGRSYMLFSHSLPSARG--NGEPLTGQLSIAPNA
HIKFMLSGA---SNDYFLVASDNGYGFIIKFTDFLTNYKNGKAVINLKENHELLNPENIVEKDSIAAFSSQGRLLIFTLSQLPNLKK-GQGNKIISISKK
PERLKLKIVPSESNIIIYSGKHFLTPGNQKDYT-GSRGQRGKKLPRGYQ---------------------------------------------------
------------
>tr|S0G1H9|S0G1H9_9DELT DNA topoisomerase 4 subunit A OS=Desulfotignum phosphitoxidans DSM 13687 GN=parC PE=3 SV=1
VTDVIEVTPVTLILSENGWIRSAKGHDIDP--------ENVKFRTGDSLRCHLRTRSDKPIVFLDSTGRSYTLYSHVLPSARS--NGEPLTGHLSLQNNA
RICFMLSET---LASHFLMASDTGYGFIIQFSDFLTHFKNGKSVITLKNDAVLMPPCPVTETDAVAAVTTKGRMLIFPLNELPRLKK-GQGNKLITIPRK
PEKIKLATLPLHANIVIHSKKHSLKPGNQADYV-KKRGTRGKLLPRGYR---------------------------------------------------
------------
>tr|A0A0F2R1P3|A0A0F2R1P3_9DELT DNA topoisomerase 4 subunit A OS=Desulfatitalea sp. BRH_c12 GN=parC PE=3 SV=1
ETEMAPVEPVTVVLSKMGWVRTAKGHDIKP--------EELIYKAGDEFLSAAYGRSNQSAIFMDSNGRTYAADPNSFPTARS--HGVPLTGSFAIDANA
RVLSVVIAE---PETEYLVASTAGYGFFSKLEEMHSRNTKGKAFLSLPEGAVPLTPIPIDIDHLVVAVTRQGRMLAFPAGELPRMAK-GKGNKIIHVLSK
DEMAFLTVLPDQCKFVIFAGKRSFTYNIVSEFS-GNRGARGKKLPRGFQ---------------------------------------------------
------------
>tr|A0A0M0I0D0|A0A0M0I0D0_9VIBR DNA topoisomerase 4 subunit A OS=Vibrio hepatarius GN=parC PE=3 SV=1
ERDLVPSEPITVVLSEKGWIRHAKGHDVDA--------EGLSYKSGDKFLASARGKSNQQAVFFGSDGRSYSLESHSLPSARS--QGEPITGRLNITAGS
NIRQVIMGE---DDQLWLVGSDAGYGFVCKGSDLLSKNRSGKALVTLPANSEVMTPNAISDSDEIVAITNQGRMLLFPIKDLPQLAK-GKGNKIINIPAA
EILSHLISVPKDATLTLYAGKRKLKPSDLDNFR-GERGRRGGLLPRGLQ---------------------------------------------------
------------
>tr|S3DKX1|S3DKX1_9GAMM DNA topoisomerase 4 subunit A OS=Candidatus Photodesmus katoptron Akat1 GN=parC PE=3 SV=1
NKYLLHNEPITVILSEKGWIRHAKGHDINA--------ESLQYKPGDRYFSHVRGKSKEQTILLSNDGRSYSLESHSLASAKG--QGEPITGRLNISENS
KIIQIFMYK---EKQLLLAGSDAGYAFVCKSSDLLSKNRNGRVLMTLPKNSKIMPLNTIKISDEILAITNHGRILIFPAKDLPQLSK-GKGNKVIHIPSS
EEFLSLISLPKDKSIDMYTKEEKFSSKELNKFR-GECGRRGSLLTENFQ---------------------------------------------------
------------
>tr|V5HF88|V5HF88_9VIBR DNA topoisomerase 4 subunit A OS=Vibrio halioticoli NBRC 102217 GN=parC PE=3 SV=1
EKDLLPNEPITVVLSEKGWIRHAKGHEVDA--------STLNYKSGDKYLTSAKGKSNQQAIFLGSDGRSYSLESHSLPSARS--QGEPITGRLNLSTGT
SIRQVLMGD---DEQLWLVGSDAGYGFVCRGSDLLSKNRNGKALVNLPQSAEVLTPSPISDQDEILAITNLGRMLMFAIKDLPQLSK-GKGNKIINIPSA
EFVTQLLAVPANATVTLYAGKRKLKPSDLDNFR-GERGRRGAMLPRGLQ---------------------------------------------------
------------
>tr|F9SHK5|F9SHK5_VIBSP DNA topoisomerase 4 subunit A OS=Vibrio splendidus ATCC 33789 GN=parC PE=3 SV=1
ERDLVPSEPITVVLSEKGWIRHAKGHEVDA--------EGLNYKSGDKFLASAKGKSNQQAVFLGSDGRSYSLESHSLPSARS--QGEPITGRLNISAGT
SIRQVVMGE---DEQLWLVGSDAGYGFVCKGSDLLSKNKSGKALVNLPQSSEVMAPSPIAESNQILAITNQGRMLLFPIKDLPQLSK-GKGNKIINIPSA
EFVSHLMAIPENATLTIYAGKRKLKPADLENFR-GERGRRGGLLPRGLQ---------------------------------------------------
------------
>tr|S7J7K9|S7J7K9_VIBFL DNA topoisomerase 4 subunit A OS=Vibrio fluvialis PG41 GN=parC PE=3 SV=1
ERDLMPSEMITVVLSEKGWIRHAKGHEVDC--------EGLNYKAGDNYLAHACGKSNQQAVFLGSDGRSYSLESHTLPSARG--QGEPITGRLNVAEGT
SIRQVVMGE---EDQLWLVGSDAGYGFVCKGTDLLSKNRSGKALVNLPDNAEVMTPQAVNQSDEILAITNQGRMLLFPIKDLPQLGK-GKGNKIINIPAA
EVVSHLLALPKDVSVTLYAGKRKLKPSDLDNFR-GERGRRGALLPRGLQ---------------------------------------------------
------------
>tr|C9P1I3|C9P1I3_VIBME DNA topoisomerase 4 subunit A OS=Vibrio metschnikovii CIP 69.14 GN=parC PE=3 SV=1
ERDLMPNEMITVVISEKGWVRHAKGHEVDC--------HSLNYKSGDNYLAHACGKSNQQVAFLGSDGRSYSLEAHTLPSARG--QGEPITGRLNITEGS
SIRQVIMGE---DDQLWLVGSDAGYGFVCKGSDLLSKNRSGKALVNLPNNSELLAPQAVNQHDEILAVTNQGRMLLFPIKDLPQLSK-GKGNKIINIPSA
EVVSHLLAIPSGSSITLYAGKRKLKPTDLDNFR-GERGRRGALLPRGLQ---------------------------------------------------
------------
>tr|A0A094PH46|A0A094PH46_COBMA DNA topoisomerase 4 subunit A OS=Cobetia marina GN=parC PE=3 SV=1
EVELMGADPITVALSEKGWIRAAKGHDIDP--------EGLSYKAGDRFHLAARGKTNQPLVLLDDTGRAYTLAAHNLPSARG--QGEPITGRMNPAAGA
AMVGLLLDA---PSARYLLASDGGYGFVTTLEQLTGKNKSGKAALTLPRGCAVLPPVEVPTALEVAVVSNEGRLLVFPLSELPEMSK-GKGNKMLSIPGE
EFVRSLVVLPAGATLVVHAGKRKTKGADLDYYR-GERGRRGSKLPKGFQ---------------------------------------------------
------------
>tr|A0A084TGB2|A0A084TGB2_9VIBR DNA topoisomerase 4 subunit A OS=Vibrio sp. ER1A GN=parC PE=3 SV=1
ERDLVPSEPITVVLSEKGWIRHAKGHDVDA--------SSLNYKAGDKYLASARGKSNQPAVFLGSDGRSYSLESHSLPSARS--QGEPITGRLNINAGT
SIRQVVMGE---ESQLWLVGSDAGYGFVCKGSDLLSKNRSGKALVTLPQGAEVITPSTIGESDEILAITNQGRMLLFPIKDLPQLGK-GKGNKIINIPSA
EFVSHLMALPQGATITLYAGKRKLKPADLDNFR-GERGRRGGLLPRGLQ---------------------------------------------------
------------
>tr|B5FB60|B5FB60_VIBFM DNA topoisomerase 4 subunit A OS=Vibrio fischeri (strain MJ11) GN=parC PE=3 SV=1
ERDLIPSEAITVVLSDKGWIRHAKGHDVDP--------TTLNYKSGDKYLAHARGKSNAPAVFMGSNGRSYALESHTLPSARS--QGEPITGRLNITAGS
QITHVVMGE---EEQTWLISSDAGYGFVCKGADLLSKNKNGKALLTLPENSQVMNPEAVSESDEILAITNEGRMLLFPIKDLPQLGK-GKGNKIINIPAA
EFLSHLLPLPQGATITLYAGKRKLKPTDLDNFR-GERGRRGSLLPRGLQ---------------------------------------------------
------------
>tr|A1ST91|A1ST91_PSYIN DNA topoisomerase 4 subunit A OS=Psychromonas ingrahamii (strain 37) GN=parC PE=3 SV=1
EKELMPSETVTVVLSTQGWVRSAKGLDVDA--------QALNYKSGDEFLTKAQGRSNQSCIFIDASGRAYSLDVHSLPSARS--QGEPLTGRFNQNENV
PFVCALIGD---DDDRYLISSDHGYGFIAKFSDINSRNKNGKTLINLTPNAQLMPPKKMTDDDWCLTISNEGRLLLFPVNSLPSLSK-GKGNRMLNIISA
EFVTMLEIIPQASSVTLHAGKRKLKPSDLVHYQ-GERGRRGSKLPRGLQ---------------------------------------------------
------------
>tr|A0A0D8Q3S0|A0A0D8Q3S0_9GAMM DNA topoisomerase 4 subunit A OS=Photobacterium iliopiscarium GN=parC PE=3 SV=1
ERDLIPSETITVVLSEKGWIRHAKGHDVDP--------NTLNYKSGDNYLAHARGKSNQPAIFLGSDGRSYALESHSLPSARS--QGEPITGRLNLTPGT
HMRQVMMAD---DDQLWLMASDAGYGFICKSSDMVSKNKSGKALLTVPEKSLVLPPQPIANNDQIMAITNEGRMLLFPIKDLPQLGK-GKGNKIINIPSA
EFLSYLTVITADSHVTLYAGKRKLKPSDLENFR-GERGRRGSMLPRGLQ---------------------------------------------------
------------
>tr|Q402B7|Q402B7_PHODP DNA topoisomerase 4 subunit A OS=Photobacterium damsela subsp. piscicida GN=parC PE=3 SV=1
ERDLIPSEPITVVLSEKGWIRHAKGHEVDP--------STLSYKSGDSYLAHARGKSNQPAIFLGSDGRSYALESHSLPSARS--QGEPITGRLNLTPGS
NMRQVMMAE---DEQLWLMASDAGYGFICKSSDMVSKNKSGKALLTLPENAQVMAPQEIREHDQILAITNEGRMLLFPIKDLPQLGK-GKGNKIINIPAA
EFLSYLQVLHDGAQVTLHAGKRKLKPSDLDNFR-GERGRRGSILPRGLQ---------------------------------------------------
------------
>tr|A0A0B9H9G2|A0A0B9H9G2_9GAMM DNA topoisomerase 4 subunit A OS=Photobacterium gaetbulicola GN=parC PE=3 SV=1
ERELIPSEAITVVLSEKGWIRHAKGHEVDP--------TSLSYKSGDGYQAHARGKSNQPAVFLGSDGRSYALESHTLPSARS--QGEPITGRLNLTPGS
QVRQVMMAD---DDQLWLMGSDAGYGFICKCSDMVSKNKNGKALLTVPENAAVMQPQCIAENDEILAITNEGRMLLFPIKELPQLGK-GKGNKIINIPAA
EFLSQLVVLPQGSHLTLHAGKRKLKPTDLDNFR-GERGRRGSMLPRGLQ---------------------------------------------------
------------
>tr|A0A0J1KA94|A0A0J1KA94_9GAMM DNA topoisomerase 4 subunit A OS=Photobacterium ganghwense GN=parC PE=3 SV=1
ERELIPSEPITVVLSDKGWIRHAKGHDVDP--------SSLSYKSGDSYLAHARGKSSQPAIFLGSDGRSYALESHTLPSARS--QGEPITGRLNLTPGS
HMRQVIMAE---DNQLWLLGSDAGYGFVCKASDMVSKNKNGKALLTVPENAEVIAPQPVQDQDEILAITNEGRMLLFPVKDLPQLGK-GKGNKIINIPAA
EFLSYLAVLPPGSHITLHAGKRKLKPSDLENFR-GERGRRGSMLPRGLQ---------------------------------------------------
------------
>tr|A0A0J1GR85|A0A0J1GR85_9GAMM DNA topoisomerase 4 subunit A OS=Photobacterium aquae GN=parC PE=3 SV=1
ERELIPSEAITVVLSEKGWIRHAKGHDVDP--------STLSYKSGDGYLCHARGKSNQPALFLGSDGRSYALESHSLPSARS--QGEPITGRLNLTPGS
QMRQVIMGE---ESQLWLMSSDAGYGFICKCADMVSKNKNGKALLTLPESSEVMPPQLVGDNDEILAITNEGRMLLFPIKELPQLGK-GKGNKIINIPSA
EFLSHLVVLPQGSHITLYAGKRKLKPSDLDNFR-GERGRRGAMLPRGLQ---------------------------------------------------
------------
>tr|Q1Z4V2|Q1Z4V2_PHOPR DNA topoisomerase 4 subunit A OS=Photobacterium profundum 3TCK GN=parC PE=3 SV=1
ERDLIPSEAITVVLSEKGWIRHAKGYDVDP--------TSLSYKSGDNYLAHARGKSNLPAILIGSDGRSYALESHSLPSARS--QGEPVTGRLNLTPGT
NLRQVLMAD---DEQMWLMGSDAGYGFICKSTDMVSKNKSGKALLTVPEKAKVMAPQPISDTDEILVITNEGRMLLFPIKDLPQLGK-GKGNKIINIPSA
EFLSQLIVLPQGEQVTIHAGKRKMKASDLDNFR-GERGRRGTMLPRGLQ---------------------------------------------------
------------
>tr|A0A0J1GFM9|A0A0J1GFM9_9GAMM DNA topoisomerase 4 subunit A OS=Photobacterium aphoticum GN=parC PE=3 SV=1
ERELIPSEAITVVLSEKGWIRHAKGHEVDP--------STLSYKSGDNYLAHARGKSNQPAIFLGSDGRSYALESHSLPSARS--QGEPITGRLNLTPGT
AMRQVMMSE---DEQLWLMGSDAGYGFICKGADMVSKNKNGKALLTVPENAEVMAPQRIADQDEILAITNEGRMLLFPIKDLPQLGK-GKGNKIINIPAA
EFLSHLVVLPQGSYLTLYAGKRKLKPSDLENFR-GERGRRGALLPRGLQ---------------------------------------------------
------------
>tr|A0A0N1J3H3|A0A0N1J3H3_PHOLD DNA topoisomerase 4 subunit A OS=Photobacterium leiognathi subsp. mandapamensis GN=parC PE=3 SV=1
ERDLIPSEAITVVLSDKGWIRHAKGHEVDP--------TTLSYKSGDNYLAHARGKSNQPAIFLGSDGRSYALESHSLPSARS--QGEPITGRLNLTPGT
NMRQVLMAE---DEQLWLMASDAGYGFICKSTDMVSKNKSGKALLTVPENAVVLPPQPVDDSDEILAITNEGRMLLFPIKDLPQLGK-GKGNKIINIPSA
EFLSYLAVIGADTHVTLHAGKRKLKPSDLYNFR-GERGRRGSMLPRGLQ---------------------------------------------------
------------
>tr|A0A0R2SZZ0|A0A0R2SZZ0_9FLAO DNA topoisomerase IV OS=Cryomorphaceae bacterium BACL22 MAG-120619-bin3 GN=ABR85_02690 PE=4 SV=1
ATELVSAEPVTVVLSERGWVRAAKGHEVDA--------AGLQYKSGDSFKQAARGKSSQFAIFLDSTGRTYSLAAHSLPSARG--QGEPLSGKVSPPSGA
TFEGVLIGD---DNKDVLLASDGGYGFVGKLSDLVSKNKAGKAVLKPSKGGLVMPPLEVADEDLIVAISNEGRMLMFPLRELPRLAK-GKGNKILGIPPA
EFVVAIAVLGAQDSITIHAGKRHHRPADLEHYA-GERGRRGNKLPRGFQ---------------------------------------------------
------------
>tr|A0A0F9W6V1|A0A0F9W6V1_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_0000830 PE=3 SV=1
EVELISSEPVTVVLSKSGWVRAAKGHDVDP--------EALQYKSGDGFKIAAKGKSNQSAVFLDSTGRAYSVQTHTLPSARG--QGEPLTGRLAPPSGA
SFEGVLMAD---DKQRVLMASDAGYGFVATVGDLQSKNKAGKSVLTLPKGARVLTPTQIQETDLLVAVTNEGRMLCFPVAELPVLAR-GKGNKIIGIPSG
EFVVSMTVLSAEGAVTVYAGRRHLKAGDLAHYH-GERGRRGNKLPRGFQ---------------------------------------------------
------------
>tr|A0A0F9Y5X8|A0A0F9Y5X8_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_0131400 PE=3 SV=1
ETELVPSEPVTVVLSEKGWVRCAKGHDVDG--------ISLSYKSGDGFLNKASGRTNQQAVFIDSSGRSYSVPAHTLPSARG--QGEPLTGRFNPPPGA
SFETVLMPE---DEALYLLASDAGYGFVAEGVDLLAKNKNGKALLSVPEGGRILPPQRVRKGSQLAAVSNEGRLLVFNLAELPQLSK-GKGNKILSLPSA
EFVAGLAVLPPGSCLVLTAGKRTLKPSDLEHYC-GERGRRGNKLPRGFQ---------------------------------------------------
------------
>tr|A0A078MEX6|A0A078MEX6_9PSED DNA topoisomerase 4 subunit A OS=Pseudomonas sp. 12M76_air GN=parC PE=3 SV=1
ETDLVPSEAVTVVLSDKGWVRCAKGHEVDG--------AALSYRAGDSFLAQASGRSNQQAVFLDSSGRSYSLMAHSLPSARG--QGEPLTGRLSPPPGA
EFVGVLLPE---DQQLYLLASDAGYGFVVQGADLQAKNKNGKALLSLPEGSRVITPVPVNDSDQVIAISNEGRLLVFPLKDLPQLPK-GKGNKILSIPSA
EYLLALALLPEGASAVLTAGKRTLKPADLEHYR-GERGRRGNKLPRGFQ---------------------------------------------------
------------
>tr|A0A0F9UE72|A0A0F9UE72_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_0233370 PE=3 SV=1
ETELVPSEPVTVVLSEKGWVRCAKGHEVDG--------PGLSYKAGDSFLAQAIGRSNQQAVFIDSTGRSYSVTTHTLPSARG--QGEPLTGRLSPPPGA
RFVNLLLPD---DEALYLLASDAGYGFIVQGADLQAKNKNGKALLSVPEGGRVIAPIAVSASDKVVAISNEGRLLVFPASELPQLGK-GKGNKILSIPSA
EFLAAITLLPQGANLILTAGKRTLRPSDLEHYQ-GERGRRGNKLPRGFQ---------------------------------------------------
------------
>tr|M5DL49|M5DL49_9GAMM DNA topoisomerase 4 subunit A OS=Thalassolituus oleivorans MIL-1 GN=parC PE=3 SV=1
ETELVSAEAVTVVLSAKGWVRAAKGHDIDA--------ENLSYKAGDSFMIAAQGKSNQNAIFLDSSGRSYSLPAHQLPSARG--QGEPLTGKLNPPAGA
SFLKVLMGK---DEEQYLLSTDAGYGFIATLADMQSKNKAGKTLITIPDNARILAPARLAEKCWIAAISNEGRMLVFPAADLPQMAR-GKGNKMISINSA
ELMVSAVAFHENDTLLVYAGKRHLKFSDLEHYQ-GERGRRGNKLPRGFQ---------------------------------------------------
------------
>tr|R4YV62|R4YV62_OLEAN DNA topoisomerase 4 subunit A OS=Oleispira antarctica RB-8 GN=parC PE=3 SV=1
ETDLLGSDPVTVVISDKGWVRAAKGHDVDV--------EGLSYKSGDKYLLSCKGKSNQNAIFIDDSGRAYSVQSHTLPSARG--QGEPLSGRLTVPSGM
GFKGLLMGP---DEDHYLMATDAGYGFITQLKEIQTKNKAGKAMLTVPTNAKVLSPARIEEKSWIVAISNEGRMLVFPAADLPVMAR-GKGNKMISIPGP
ELMISAVAFGETDTLLVHSGKRHTKFSDLEHYF-GERGRRGNKLPRGFQ---------------------------------------------------
------------
>tr|A0A067BE61|A0A067BE61_9VIBR DNA topoisomerase 4 subunit A OS=Vibrio metoecus GN=parC PE=3 SV=1
ERDLMPSEAITVVLSEKGWIRHAKGHDVDG--------QSLSYKAGDNYLTHACGKSNQQAVFLGSDGRSYSLESHTLPSARG--QGEPITGRLNVAEGT
TIRQVVMGE---EDQLWLVGSDAGYGFVCKGDDLLSKNRSGKALINLPENSEVMTPQVIADKDEILAITNQGRMLLFPIKDLPQLSK-GKGNKIINIPAA
EVLSNLMVLPQGASITLYAGKRKLKVSDLDNFR-GERGRRGALLPRGLQ---------------------------------------------------
------------
>tr|A0A0C2NKW1|A0A0C2NKW1_9VIBR DNA topoisomerase 4 subunit A OS=Vibrio sp. DCR 1-4-12 GN=parC PE=3 SV=1
ERDLVPSEPITVVLSEKGWIRHAKGHEVDG--------EGLSYKSGDQYLALARGKSNQQAVFLGSDGRSYSLESHSLPSARS--QGEPITGRLNVAPGT
SVRQVVMGE---DDQLWLIGSDAGYGFVCKGSDLLSKNRSGKALVSLPQNAQVTVPQRISDNDEILAITNQGRMLLFPMKELPQLSK-GKGNKIINIPAA
EVVSHLISIPRNSTVTLYAGKRKLKPSDLENFR-GERGRRGGLLPRGLQ---------------------------------------------------
------------
>tr|A0A0F2I4I7|A0A0F2I4I7_9VIBR DNA topoisomerase 4 subunit A OS=Vibrio sp. S234-5 GN=parC PE=3 SV=1
ERDLLPNETITVVLSEKGWIRHAKGHEVDC--------EGLSYKAGDSYLAHACGKSNQQVVLFGSDGRSYSLESHTLPSARG--QGEPITGRLNITPGS
SIRQLVMGE---EDQLWLVGSDAGYGFVCKGSDLLSKNRSGKALVTLPENAEVMTPSAVLDNDDILAITNQGRMLMFPIKDLPQLGK-GKGNKIINIPAA
EVLSHLVALPKGVSLTLYAGKRKLKPSDLENFR-GERGRRGGLLPRGLQ---------------------------------------------------
------------
>tr|A0A0M0IKN2|A0A0M0IKN2_9VIBR DNA topoisomerase 4 subunit A OS=Vibrio xuii GN=parC PE=3 SV=1
ERDLVPSEPITVVLSEKGWIRHAKGHDVDA--------EGLNYKSGDNYLAHARGKSNQQAVFLGNDGRSYSLESHSLPSARS--QGEPITGRLNINAGT
SIRHVVMGE---EEQLWLIGSDAGYGFVCKGSDLLSKNKSGKALVTLPANSEVISPQTISDTDEILTITNQGRMLLFPIKDLPQLGK-GKGNKIINIPAA
EYVSHLISLPQGSAVTLYAGKRKLKASDLENFR-GERGRRGGLLPRGLQ---------------------------------------------------
------------
>tr|A0A0B8P6Y3|A0A0B8P6Y3_9VIBR DNA topoisomerase (ATP-hydrolyzing) OS=Vibrio sp. JCM 19232 GN=JCM19232_1792 PE=4 SV=1
EKDLLPSEPITVVLSEKGWIRHAKGHEVDA--------STLNYKSGDKYLASARGKSNQQAVFLGSDGRSYALESHSLPSARS--QGEPITGRLNISTGT
TIRQVLMGE---DDQLWLVGSDAGYGFVCKGNDLVSKNRSGKALVNLPQGAEIMQPDQIADQDEILAITNQGRMLMFPIKDLPQLGK-GKGNKIINIPSA
EVLSHLAVVPAGASITLFAGKRKLKPSDLENFR-GERGRRGSMLPRGLQ---------------------------------------------------
------------
>tr|E3BQF8|E3BQF8_9VIBR DNA topoisomerase 4 subunit A OS=Vibrio caribbeanicus ATCC BAA-2122 GN=parC PE=3 SV=1
ERDLVPSEPITVVLSDKGWVRHAKGHELDP--------ATLNYKSGDKYLAHARGKSSQPVVLLGSDGRSYSLESHSLPSARS--QGEPITGRLNISSGS
NIRHLVMGE---EEQLWLVGSDAGYGFVCKGSDLLSKSKSGKALVNLPESSEVLPPYAIGDSDEILAVTNQGRMLLFPIKDLPQLGK-GKGNKIINIPAA
EFVSHLIALPKGRTVTLYAGKRKLKESDLDSFR-GERGRRGGLLPRGLQ---------------------------------------------------
------------
>tr|A0A0L7YVA4|A0A0L7YVA4_VIBAL DNA topoisomerase 4 subunit A OS=Vibrio alginolyticus GN=parC PE=3 SV=1
ERDLVPSEAITVVLSEKGWVRHAKGHDVDC--------QGLNYKSGDQYLAHACGKSNQQAVFLGSDGRSYSLESHSLPSARS--QGEPITGRLNITEGS
SIRQVVMGE---DDQLWLVGSDAGYGFVCKGSELLSKNRSGKALVNLPENSEIMPPQAIGDADEILAITNQGRMLLFPIKDLPQLSK-GKGNKIINIPAA
EFVSHLMSLPQGVSITLYAGKRKLKASDLDNFR-GERGRRGGLLPRGLQ---------------------------------------------------
------------
>tr|S5INE5|S5INE5_VIBPH DNA topoisomerase 4 subunit A OS=Vibrio parahaemolyticus O1:Kuk str. FDA_R31 GN=parC PE=3 SV=1
ERDLVPSEPITVVLSEKGWVRHAKGHDVDA--------ESLNYKSGDKYLAHARGKSSQPAVFLGSDGRSYSLESHSLPSARS--QGEPITGRLNITAGS
SIRQVIMSE---EDQLWLVGSDAGYGFVCKGADLLSKNRSGKALVTLPANSEVMTPKEVGDSDEILAITNQGRMLLFPIKDLPQLAK-GKGNKIINIPAA
EVLSHLIALPQGASLTLYAGKRKLKPADLENFR-GERGRRGSLLPRGLQ---------------------------------------------------
------------
>tr|U3A5K0|U3A5K0_VIBPR DNA topoisomerase 4 subunit A OS=Vibrio proteolyticus NBRC 13287 GN=parC PE=3 SV=1
ERDLVPSEPITVVLSEKGWIRHAKGHDVNA--------EGLNYKSGDKYLAHAIGKSNQQAVFLGSDGRSYSLESHSMPSARS--QGEPITGRLNISAGT
HVRQVVMGE---EDQLWLIGSDAGYGFVCKGADMLSKNRSGKALVTLPQNSEIMTPQSINDSDEILAITNQGRMLLFPIKDLPQLGK-GKGNKIINIPAA
EFVSHLMALPQGCSVTLYAGKRKLKPADLENFR-GERGRRGSLLPRGLQ---------------------------------------------------
------------
>tr|W4MEJ6|W4MEJ6_9DELT DNA topoisomerase 4 subunit A OS=Candidatus Entotheonella sp. TSY2 GN=parC PE=3 SV=1
ETTLVTNEPVTVILSEKGWIRAAKGHEIDP--------TTLSYKAGDAFLAAARGKSTQLAVFLDSSGRTYAVPAHTLPSARG--QGDPLTGRVSPPDGA
SFVSVLLGN---PEELYVLATDAGYGFVVTLGDLHTRQRAGKVVLTVGPDSRILPPIPLVTADMVAVVSNAGRLLVFPLTELPQLSK-GKGYKLIGLSSD
EVVASLICFQSGQPLTLYCGQRHLKPADIERYS-GVRGRRGSKLPRGFQ---------------------------------------------------
------------
>tr|U4KCF0|U4KCF0_9VIBR DNA topoisomerase 4 subunit A OS=Vibrio nigripulchritudo GN=parC PE=3 SV=1
ERDLMPSEPITVVLSEKGWIRHAKGHDVDA--------EGLNYKSGDKYLAHARGKSNQQAVFLGTDGRSYSLESHSLPSARS--QGEPITGRLNITAGT
TISRVIMGE---EEQLWLVGSDAGYGFVCKGSDLLSKNRSGKALVNLPQGSEVMTPSAIADQDEILAITNQGRMLIFPMKDLPQLSK-GKGNKIINIPSA
ETVSHLMSLPSGVSVTIYAGKRKLKPTDLDNFR-GERGRRGSLLPRGLQ---------------------------------------------------
------------
>tr|A0A084CMQ7|A0A084CMQ7_9GAMM DNA topoisomerase 4 subunit A OS=Candidatus Photodesmus blepharus GN=parC PE=3 SV=1
LTNLAPTEPITVILSEKGWIRYAKGHDINT--------KSLKYKSGDSYFTHAYGKSNQHIIFLSNDGRSYSLEPNSLPSART--QGEPITGRLNINTPT
KIRQIIMST---DEQFWLVGSDAGYAFICKGTNFLSKNRSGKTLVYLPKNSKMIIPNKINDSDEILAITNQGRILLLSAKSLPILSK-GKGNKIIKVPNN
RNFISLIVLSQGESITLYSEKRKLKPKDIRDLH-EENDNKGKLLPKELQ---------------------------------------------------
------------
>tr|U3A6D2|U3A6D2_9VIBR DNA topoisomerase 4 subunit A OS=Vibrio azureus NBRC 104587 GN=parC PE=3 SV=1
ERDLVPSEPITVVLSEKGWIRHAKGHEVDA--------QGLSYKSGDKYLAHARGKSNQQAVLFGSDGRSYAIESHTLPSARS--QGEPITGRLNITAGS
SIRQVIMGE---EEQLWLVGSDAGYGFVCKGSDLLSKNRSGKALITLPANAEVMTPKAIADSDEILAITNQGRMLLFPIKDLPQLAK-GKGNKIINIPSA
EVLSHLMALPQGASLTLYAGKRKLKQADLDNFR-GERGRRGGLLPRGLQ---------------------------------------------------
------------
>tr|C4L9W3|C4L9W3_TOLAT DNA topoisomerase 4 subunit A OS=Tolumonas auensis (strain DSM 9187 / TA4) GN=parC PE=3 SV=1
EKELTPSELVTVVVSEMGWVRAAKGHDVDV--------QGLNYKAGDGYLVSAQGRSNQQTVFMTNLGRTYSLEAHTLPSARG--QGEPLTGKLSFTAGE
QTRYVLLGN---EDERYLICSDAGYGFLCEYNDLISKNKNGKALLTLPEGAQVLPPQLTADDALCLVISNEGRMLLFPLNTLPQLGK-GKGNKLIGIPAD
EFVTHVAVVKADQAVTLYAGKRKLKPADMVLYH-GERGRRGAKLPRGLQ---------------------------------------------------
------------
>tr|N9U5X4|N9U5X4_9GAMM DNA topoisomerase 4 subunit A OS=Aeromonas diversa CDC 2478-85 GN=parC PE=3 SV=1
EKELTPSEPVTVILSAAGWIRAAKGHDVDS--------AGLSYKAGDQFLCDALGRSNQQAVFLSTLGRSYSLEAHTLPSARS--QGEPLTGRFALSPGE
EVHHVVMGS---EQEPYLLSTDAGYGFVCSYEDMIGKNKNGKALLSVPEGGQVLAPQPIKPSDLCMAISNEGRMLLFPLSTLPVLGK-GKGNKIISIPSA
EFVTQLAVVPAGQSVTLFAGKRKLKPSDLEYYR-GERGRRGAKLPRGLQ---------------------------------------------------
------------
>tr|R1IS48|R1IS48_9GAMM DNA topoisomerase 4 subunit A OS=Grimontia indica GN=parC PE=3 SV=1
ERDLIPSEPITVVLSEKGWIRHAKGHDVDA--------TTLSYKSGDNYLASARGKSNQPAVFIGTDGRSYALESHSLPSARS--QGEPITGRLNITAGT
TVRHVMMGE---NDHLVLMASDAGYGFVCKQDDLLSKNRSGKALLSLPQAAEVMAPQRVFDNDDIVAITNEGRMLVFPVKELPQLGK-GKGNKIINIPSA
ELLAQLFVIPQGSTVTLHAGKRKLKPADMDNFR-GERGRRGSMLPRGLQ---------------------------------------------------
------------
>tr|A0A0M4L609|A0A0M4L609_9GAMM DNA topoisomerase 4 subunit A OS=Candidatus Thioglobus singularis PS1 GN=parC PE=3 SV=1
DQDMMPAENVTVVLSEKGWVKAAKGHEIDS--------SALNYKSGDAFLKDAKGRSNKMAFFIDSSGRSYTILANSLPSARG--QGEPLTGRLTPPIGA
EFIDVVMGD---DEQLVILSSDAGYGFISTLGDLQSKTKSGKHAITLSKQAKTMRVTKVQESDYVAVITNRARLLIFPVIELPQLSK-GKGNKLIQIKTD
EFLIGICTIKDNQKLRVEYGKKHKSFEDLVNFT-SHRARKGLTIPGVHG---------------------------------------------------
------------
>tr|A0A0F5ARA1|A0A0F5ARA1_9GAMM DNA topoisomerase 4 subunit A OS=Salinivibrio sp. KP-1 GN=parC PE=3 SV=1
ERDLVPSEPITVVLSDKGWIRHAKGHDVDA--------TGLNYKAGDKFLDAAPGKSNQPAVFLGSDGRSYAIESHTLPSARS--QGEPITGRINITPGS
SIRHVLMAD---EGQLTLVASDAGYGFVCKQADMLSKNRSGKALLTVPDQAEVMPPRQVGESDLIVAISNEGRMLVFPVHELPQLSK-GKGNKIINIPGA
EVLSQLYVVPANAGVTLHAGKRKLKPDDLTHYR-GERGRRGSMLPRGLQ---------------------------------------------------
------------
>tr|S6GDD9|S6GDD9_9GAMM DNA topoisomerase 4 subunit A OS=Osedax symbiont Rs1 GN=parC PE=3 SV=1
EKDLLSADPVTAVISKQGWIRAAKGHDIDA--------LGLSYKSGDSFKIACQGRMNQPLILLDSTGRSYTIETHNLPSARG--QGEPITGRISMPKGA
TIDAAVTGP---DSDKIILSSDAGYGFLTTIADLSSKTKNGKAALTLSKNAQILSAINTLADKLLAAVTNEGRMLVFRVADLPELSK-GKGNKIINVPTA
ELLIELIVFNPADTLLVHSGKQHLKPSDIQHFM-GERGRRGNKLPRGYQ---------------------------------------------------
------------
>tr|A0A063Y232|A0A063Y232_9GAMM DNA topoisomerase 4 subunit A OS=Nitrincola lacisaponensis GN=parC PE=3 SV=1
EKDLLSADPVTVVLSKQGWVRAARGHDIDA--------AGLSYKSGDAFKLACPGRMNQPTILLDSTGRSYTLDTHTLPSARG--QGEPVTGKLSLPKGA
TIDGMICGA---EGDRVLLASDAGYGFVTRIADLSSKTKNGKAALSLPKNSQVLSPVRIQQQDLLVAVTNEGRMLVFPVSELPELAK-GKGNKILNIPSA
ELLVAVAVLSPDDQLQVISGRQHLKGADLEHYR-GERGRRGNKLPRGYQ---------------------------------------------------
------------
>tr|S6HED7|S6HED7_9GAMM DNA topoisomerase 4 subunit A OS=Osedax symbiont Rs2 GN=parC PE=3 SV=1
ETDLLSAEPVTAVISKQGWIRAAKGHDIDC--------AGLSYKSGDSFKLACQGRMNQSLILLDSTGRSYTIETHNLPSARG--QGEPVTGRISMPKGA
TIDAAVTGG---EQCKVLLSSDAGYGFLTTIADLSSKTKNGKAALSLSKNAQLLTSTNIDGDKMLAAVTNEGRMLVFAVADLPELAK-GKGNKIINVATA
ELMIALVVFNPGDTLLVHSGKQHLKPADIAHFC-AERGRRGNKLPRGYQ---------------------------------------------------
------------
>tr|Q2BR51|Q2BR51_NEPCE DNA topoisomerase 4 subunit A OS=Neptuniibacter caesariensis GN=parC PE=3 SV=1
EKDLLSSDPVTVVISKQGWIRAAKGHEIDA--------VGLNYKSGDAFKLACKGRTNQPTILLDTTGRSFTIETHNLPSARG--QGEPVTGRITLPKGS
TIDAAVAGK---DADKILMASDAGYGFVAKISDLTSKTKNGKAALTLPKNANIISPIKVAETDLLAAVTNEGRLLVFPVSELPELAR-GKGNKIINIPSA
ELVVALATLSKDDTLMVHAGKQHLKPSDIEHYR-GERGRRGNKLPRGYQ---------------------------------------------------
------------
>tr|A0A081G1A1|A0A081G1A1_9ALTE DNA topoisomerase 4 subunit A OS=Marinobacterium sp. AK27 GN=parC PE=3 SV=1
EKDLLSADPVTVVISKQDWIRAAKGHDIDA--------EGLSYKAGDGFKLACKGRMNQPTILVDSTGRSYTLDTHTLPSARG--QGEPVTGKLTLPKGA
VIEGMTAGR---EADQVLMASDAGYGFVTRIEDLTSKTKNGKAVLTLPKAARVLPPVRVSESDLLAAISSSGRLLIFPVSELPQLGR-GKGNKIINIPSS
ELMVALQTFAPGDTLVVHAGRQHLKGTDLEHYR-GERGRRGNKLPRGFQ---------------------------------------------------
------------
>tr|G7ER17|G7ER17_9GAMM DNA topoisomerase 4 subunit A OS=Pseudoalteromonas sp. BSi20311 GN=parC PE=3 SV=1
EKDLIPSESVTVVLSDKGWARVGKGHDLDV--------EGLNYRAGDGYRASARGKSNQPAVFLDSAGRAFATDAHSLPSARS--QGEPMTGRFNLTSGA
SFEHVVMGE---DAQVLLMASDAGYGFITDFKDLVSKNKNGKALVSVPKGGVLLSPIRVNATDYCMAISNEGRMLLFPLRDLPKLGK-GKGNKIISIPGA
EFVKVLAVVPQGSSVTLHAGKRKLKPSDLEHYH-GERGRRGNKLPRGLQ---------------------------------------------------
------------
>tr|N6WWU8|N6WWU8_9ALTE DNA topoisomerase 4 subunit A OS=Marinobacter nanhaiticus D15-8W GN=parC PE=3 SV=1
EVDLVSNDPVTVVLSEKAWVRAAKGHDIDP--------EGLSYKAGDRFALAAKGRNNQQAIFLDSTGRAYSLMAHSLPSARG--QGEPLTGRINPPPGA
TFAGVMMGD---PRHRVLLVTDGGYGFVSNLDNLISKNRNGKAVVSVPKGARVMAPIMVPDDLHLGAITNEGRMLVFPLSELPELAK-GKGNKIISIPSA
EFVVAVCVFRPADQLVVQAGKRKMQFSDLEHYI-GERGRRGHKLPRGLQ---------------------------------------------------
------------
>tr|A4BAP5|A4BAP5_9GAMM DNA topoisomerase 4 subunit A OS=Reinekea blandensis MED297 GN=parC PE=3 SV=1
ETEILPSEAVTVVLSERGWIRSGKGHELEP--------EGLNYKSGDSFAFAARGKSNQATVLLDSTGRSYSLQTHTLPSARG--QGEPITTRLNPPPGA
AMKGLLLGN---PDDQYLLTSDAGYGFIGKLSDMVSKNKAGKALLSLPKGAEVMPPQPVKSTDYLAAISNEGRLLVFPVRDLPELAK-GKGNKIINIPSS
ELMVGAVVLGADDTLLVYAGKRKLRGSDLEHYL-GERGRRGNKLPRGFQ---------------------------------------------------
------------
>tr|A0A0C5VQJ4|A0A0C5VQJ4_9GAMM DNA topoisomerase 4 subunit A OS=Gynuella sunshinyii YC6258 GN=parC PE=3 SV=1
EEQLVSADPVTVILSRKGWIRSAKGHDFDV--------SGLAYKSGDEYASSVRGKSNQNVLLLDSTGRSYSVAAHTLPSARG--QGEPLSGRINPPPGA
EFKGMLMGA---ADQQVLLCTTAGYGFVARLEDLDSKNKAGKAVINVPDGAEVMMPSMVRETDLIAVVSNEGRLLVFPVQDLPELAK-GKGNKMIGIPTD
EYMIGAIIVSTDDILVISAGKRNLRSADLEHYR-GERGRRGNKLPRGFQ---------------------------------------------------
------------
>tr|Q2SBA1|Q2SBA1_HAHCH DNA topoisomerase 4 subunit A OS=Hahella chejuensis (strain KCTC 2396) GN=parC PE=3 SV=1
ETDLIASEPVTVVLSEKGWVRAAKGHDIDA--------QGLSYKAGDKFLAAAKGRSHQNAIFLDDTGRSYCVAAHSLPSARG--QGEPLTGRVNPPSGA
GFTHVLMGP---DSMKVVLASDAGYGFVARLEDLQSKNRAGKALISLPKGACVSPPILLENNPHLVAISNEGRMLVFPVSELPELAK-GKGNKIIGIPSA
EVMSNLAVVGEKDTLVLHAGKRFLTFDDLSHYL-GERGRRGHKLPRGLQ---------------------------------------------------
------------
>tr|J4KTB3|J4KTB3_9GAMM DNA topoisomerase 4 subunit A OS=SAR86 cluster bacterium SAR86B GN=parC PE=3 SV=1
EEETLVTESITVVLSEAGWIRSAKGHEIDP--------SSLSYRGEDKLQDFCRGKSNQLAVFLDSNGKAYSLPSHSLPSARG--MGDPISGRVSADSGV
RFISTLIGN---DNDKYMIMNTAGYGYISEFQNMVSNKKSGRAFMKLPNQAELLKALKVRDHVYIAAVSNIGRLLIFKIDELPVLAK-GKGNKIINIPTP
EFMAHAQLISPSSSLRIESGKRFLKLKDLENYI-SSRAKRGNMLPQGYR---------------------------------------------------
------------
>tr|Q4PK96|Q4PK96_9BACT DNA topoisomerase (ATP-hydrolyzing) OS=uncultured bacterium MedeBAC35C06 PE=3 SV=1
EEETIVTEPVTIVLSKAGWIRSAKGHEIDP--------SSLSYRGDDLLQDFCRGKSNQNTVFLASNGKAYTLSAHSLPSARG--LGDPITGRISADSGI
IFKSCAIGE---QEDKYVVSNSAGFGYISDFASMISNKKSGRAFMKVPEGADVHKAIKYRDHEFIVAISNIGRMLIFNIEELPFLQK-GKGNKIINIPTP
ESMTHIELLAPESILRIDSGKQHMKFKDLQNYI-STRAKRGNMLPQGYR---------------------------------------------------
------------
>tr|Q9F7N9|Q9F7N9_PRB01 DNA topoisomerase 4 subunit A OS=Gamma-proteobacterium EBAC31A08 GN=parC PE=3 SV=1
EEETLVTEPITVVLSAAGWIRSAKGHEIDP--------SSLSYRGEDVLQDYGRGKSNQVSVFLDSNGKAYSLASHSLPSARG--MGDPITGRVSADSGV
KFISSLIGN---DEDKFMIMNTAGYGYISEFKNMVSNKKSGKAFMKIPHEADLLKAIKVRDHLYIAAVSNIGRLLIFKIDELPTLGK-GKGNKIINIPTA
ELMTHAQLVSEASSLRIESGKRFLKLKDLENYI-STRAKRGNMLPQGYR---------------------------------------------------
------------
>tr|A0A0R2WFU7|A0A0R2WFU7_9GAMM DNA topoisomerase IV OS=SAR86 cluster bacterium BACL1 MAG-121015-bin70 GN=ABS19_00205 PE=4 SV=1
EEEMVTSEPVTVVLSKGGWIRSAKGHDIDP--------TGLTFRGDDSLQHFAKGKNNQSAVFFDSGGKAFALAAHSLPSARG--LGEPLTGRVASASGV
TFIGAAIGA---DSSKILIANSAGYGFVSELSNAISNQKKGKAFMKLPEKAALLPPVPLESHKHIVAISSIGRMLIFDVSELPVLPK-GKGNKIINIPKP
ESMSFICLLSDSSTLQIHSGKRFMKLKDLENYI-STRAKRGMMLPQGYR---------------------------------------------------
------------
>tr|K6H322|K6H322_9GAMM DNA topoisomerase 4 subunit A OS=SAR86 cluster bacterium SAR86E GN=parC PE=3 SV=1
EEEVVTSEPVTVILSKAGWIRSAKGHDIDP--------TSLAFRGDDKLQHSAQGRNNQTTVFFDSGGKAFSLPAHSLPSARG--MGEPITGRVTAESGV
TFEGVAIGT---EESKILISNSAGFGFISNLSNAISNQKKGKQFMKTPEGASVISPIAIHSHKFVAATFVSNKMLIFPIDELPVLPK-GKGNKLISISTK
EFMMDVCCLAEDSKLHIHHEGKGKTLKELEEYV-SSRAKRGRVLPAGYN---------------------------------------------------
------------
>tr|F6CVY0|F6CVY0_MARPP DNA topoisomerase 4 subunit A OS=Marinomonas posidonica (strain CECT 7376 / NCIMB 14433 / IVIA-Po-181) GN=parC PE=3 SV=1
EEDLLSNDPITVVISKQGWVRAAKGHDIDV--------YGLSYKSGDEFLISTKGRSNQTLVLVASNGRTYSIKAHTLPSARG--QGEPITGRISLEKDS
TIVAAVLDK---EEAHYLVASDAGYGFVAQLKDLYAKNKAGKATLSLPAGAKVLSPVAVSETGRVVAISNEGRMLVFDVASLPQMAK-GKGNKMISIPSA
ELVVAMACVQPEDLLVALSGKRFMTEKDLQEYM-GERGRRGLKLPRGFQ---------------------------------------------------
------------
>tr|A0A0K6IGU6|A0A0K6IGU6_9GAMM DNA topoisomerase 4 subunit A OS=Marinomonas fungiae GN=parC PE=3 SV=1
EEDLLSNDPITVVLSKQGWIRAAKGHDIDE--------RGLSYKSGDEFLLSTKGRSNQTLVLFASNGRTYSLKAHTLPSARG--QGEPITGRISLEKDT
HIVAAALDN---DDAYYLVGSDAGYGFVSKLGDLHAKNKAGKATLSLPTNAEVLPPVKIAETARAVVVSNEGRMLAFSVASLPQMAK-GKGNKMLSISST
EWVCAMASIQPDDLLLAHSGKRFTTEKELIDYI-GERGRRGLKLPRGFQ---------------------------------------------------
------------
>tr|F2JY19|F2JY19_MARM1 DNA topoisomerase 4 subunit A OS=Marinomonas mediterranea (strain ATCC 700492 / JCM 21426 / NBRC 103028 / MMB-1) GN=parC PE=3 S
EEDLLSNDPVTVVLSKQGWIRAAKGHDIDV--------TGLSYKSGDEFLLSAKGRTNQTLVLIASNGRTYSLKAHTLPSARG--QGEPITGRISLEKGA
TIVAAVLDS---EEAHYLLASDAGYGFVAQLKDLYAKNKAGKATLSLPSNAEVISPVKVEEGDKVVVVSNEGRMLAFSVKSLPQMAK-GKGNKMLSIPSS
ELVIAMATIQSNDLLVAHSGKRFLAEKDLQEYV-GERGRRGLKLPRGFQ---------------------------------------------------
------------
>tr|I5B229|I5B229_9DELT DNA topoisomerase 4 subunit A OS=Desulfobacter postgatei 2ac9 GN=parC PE=3 SV=1
VTDVIEVEPVTIILSANGWIRTAKGHDIDP--------ANVKFRTGDHLLCHLRTRSDKPIVLIDTSGRAYTLFSHALPSARG--NGEPVTGHLTLAQDT
SICYMITGE---DEDLFINGADNGYGYIIKFSDFFTNFKNGKAVITLSENDLPIAPLPIPNSDSVAAITTGGRMLIFPVNQLPHLKK-GKGNKIIHIPVS
PEKLKLKILPLSSNLVIYSGKHLLTPGNQQDYT-STRGRRGKLLPRGYR---------------------------------------------------
------------
>tr|W1S087|W1S087_9GAMM DNA topoisomerase 4 subunit A OS=Marinomonas profundimaris GN=parC PE=3 SV=1
EEDLLSNDPITVVISKQGWVRAAKGHDIDV--------HGLSYKSGDEFLVSAKGRSNQTLVLLASNGRTYSVKAHTLPSARG--QGEPITGRISLEKDA
TIVSMILDS---EDAHYLVASDAGYGFVAQLKDLYAKNKAGKATLSLPKGAQVMAPVLVQEQGRVVAISNEGRMLAFDVASLPQMAK-GKGNKMISIPSA
ELVVAMACVQPNDLLTAYAGKRFMAEKDLEEYL-GERGRRGLKLPRGFQ---------------------------------------------------
------------
>tr|E8LH89|E8LH89_9GAMM DNA topoisomerase 4 subunit A OS=Succinatimonas hippei YIT 12066 GN=parC PE=3 SV=1
EDDLMPSTPVTVILSKMGWVRQASEYNADA--------EHMTYRAGDGFKDKASGRSNQQAVFITNLGRAYSVDIRELPSARG--QGEPLSSKVNLQQGE
FAEYVIIGQ---SNDYFLLASDKAYGFICKYEDILTRLKGGRALVSLDADAKLFAPIKLSSSDLLAVASRQGKLLIYKAEDLPVLPR-GKGNKLISIAGA
DGVAAVAVLPEGSSIIIHCGKRILSASEITERL-SVRTKRGDTLPRGFQ---------------------------------------------------
------------
>tr|L8D6N2|L8D6N2_9GAMM DNA topoisomerase 4 subunit A OS=Pseudoalteromonas luteoviolacea B = ATCC 29581 GN=parC PE=3 SV=1
EKELIPTEAVTVVLSDKGWARLAKGHDIDA--------AGLSYRAGDSFKAQAHGRSNQPAVFLDSSGRAFATDAHSLPSARS--QGEPMTGRFNLGSGC
NFEHVVMGD---DKHMYLMATDGGYGFITEFADLVSKNKNGKALVTVPNGAILLAPISVNSTDLCMAISSEGRMLLFPLRDLPKLGK-GKGNKIISIPSA
EFVKVLAVVPLGASVTLHAGKRKLKPSDLEHYY-GERGRRGNKLPRGLQ---------------------------------------------------
------------
>tr|A0A0C1Q5Q6|A0A0C1Q5Q6_9GAMM DNA topoisomerase 4 subunit A OS=Pseudoalteromonas luteoviolacea GN=parC PE=3 SV=1
EKDLIPSEAVTVVLSEKGWARFAKGHDIDA--------EGLNYRSGDSYKASAKGKSNQPAVFLDSSGRAFATDAHSLPSARS--QGEPMTGRFNLAAGV
NFEHVVMGE---EQELYLMATDAGYGFIAEFNDLVSKNKNGKALVSIPKGAELIAPISVNATDRCMAISNEGRMLLFPLRDLPKLAK-GKGNKIISIPSA
EFVKVLAVVPDGRAVTLYAGKRKLKNSDLEHYF-GERGRRGNKLPRGLQ---------------------------------------------------
------------
>tr|A0A0F4PLY2|A0A0F4PLY2_9GAMM DNA topoisomerase IV subunit A OS=Pseudoalteromonas ruthenica GN=TW72_11605 PE=3 SV=1
EKDLIPSESVTVVLSEKGWARVAKGHEVDA--------EGLNYRAGDKFKASAKGKSNQPAVFLDSSGRAFATDAHSLPSARS--QGEPMSGRFNIAAGA
TLEHAVMAE---NEQLLLMASDAGYGFVAEFADLVSKNKNGKALVSLPKGGLLLQPIAVNSKDYCMAISSEGRMLLFPLRDLPKLAK-GKGNKIISIPSA
EYVKLLTVVPEGASVTLHAGKRKLKPADLEHYY-GERGRRGNKLPRGLQ---------------------------------------------------
------------
>tr|U1JT27|U1JT27_PSEO7 DNA topoisomerase 4 subunit A OS=Pseudoalteromonas piscicida JCM 20779 GN=parC PE=3 SV=1
EKDLIPSESVTVVLSEKGWARFAKGHDIDA--------EGLSYRSGDSYKASAKGKSNQPAVFLDTSGRAFATDAHSLPSARS--QGEPMTGRFNLASGC
NFEHVVMGE---EKSTYLMATDGGYGFISDFADMVSKNKNGKAFVSVPKGAHLMAPIQVFATDMCMAISSEGRMLIFPLRDLPKLGK-GKGNKIISIPSA
EFVKVLAVVPEGVSVTLHAGKRKLKPSDLEHYY-GERGRRGNKLPRGLQ---------------------------------------------------
------------
>tr|U1JS53|U1JS53_9GAMM DNA topoisomerase 4 subunit A OS=Pseudoalteromonas citrea DSM 8771 GN=parC PE=3 SV=1
EKDLIPSEAVTVVLSEKGWARVAKGHDIDA--------QGLNYRSGDTYKGAAKGKSNQPAVFLDTSGRAFATDAHSLPSARS--QGEPMTGRFNLAPGC
NFEHVLMGE---DNTLLLMATDGGYGFITEFTDLISKNKNGKALVSVPKGAELIAPIEVHATDMCMAISNEGRMLLFPLRDLPKLAK-GKGNKIISIPSA
EFVKVLACVPAGSAVTLHAGKRKLKPSDLEHYY-GERGRRGNKLPRGLQ---------------------------------------------------
------------
>tr|A0A0P9HJI4|A0A0P9HJI4_9GAMM DNA topoisomerase 4 subunit A OS=Pseudoalteromonas sp. P1-9 GN=parC PE=4 SV=1
EKDLMPSESVTVVLSEKGWARCAKGHDIDA--------EGLSYKSGDSFKSLAKGRSNQPSVFLDSSGRAFATDTHSLPSARS--QGEPMTGRFNVAPGA
NLEHVVMGE---EKANFLMASDAGYGFITEFNDLVSKNKNGKALVTIPEAALLMTPQSIHTTDRCLAISNEGRMLIFPIRDLPKLGK-GKGNKIISIPSA
EFVKVLGIVPDGASVTLHAGKRKLKPSDLEHYY-GERGRRGNKLPRGLQ---------------------------------------------------
------------
>tr|A4C958|A4C958_9GAMM DNA topoisomerase 4 subunit A OS=Pseudoalteromonas tunicata D2 GN=parC PE=3 SV=1
EKDLIPSEAVTVVLSEKGWARCAKGHDIDA--------AALSYRAGDEFKALAKGRSNQPVVFLDSSGRAFCTDAHSLPTARS--QGEPMTGRFNMSTGV
NFEHVVMGE---LDAMFLMASDAGYGFVASFADLVSKNKNGKALVSLSTGAQLISPIKVNTTDNCLAISNEGRMLMFPLRDLPKLGK-GKGNKIISIPSA
EFVSVIAVVPKESAVTLHAGKRKLKAADLEHYL-GERGRRGNKLPRGLQ---------------------------------------------------
------------
>tr|M1F9D1|M1F9D1_9ALTE DNA topoisomerase 4 subunit A OS=Marinobacter sp. BSs20148 GN=parC PE=3 SV=1
NIDLVSNDPVTIVLSEKGWVRAAKGHDIDP--------LGLSYKAGDKFSLQVHGRNNQQVIFLDSTGRAYALMAHSLPSARG--QGEPLSGHINPPPGA
QFCGLLMGD---SQRKVVLVTDGGYGFATSLGDMLSKNRNGKTLVSVPKGAHLMAPVMVPETLYVAAVSNEGRMLVFPLTELPELVK-GKGNKLISIPSA
EFVVAVAVFAHSDQLEIHAGKRKMQFSDLEHYL-GERGRRGHKLPRGLQ---------------------------------------------------
------------
>tr|A0A0P8AWM4|A0A0P8AWM4_9ALTE Topoisomerase IV subunit ParC OS=Marinobacter sp. HL-58 GN=parC PE=4 SV=1
ETELVSNDPVTVVLSEKGWVRAAKGHDIEP--------EGLSYKAGDKFAMAAKGRNNQQAVFLDSTGRAYSLVAHSLPSARG--QGEPLSGRINPPSGA
TFSGLLMGD---PARKVLLVTDGGYGFVTSLNDMISKNRNGKAVVSVPKGARIMAPVVVPDPLYLGAISNEGRMLVFPLSELPELAK-GKGNKIISIPSA
EYVVAIAVFAEDDQLEIRAGKRKMQFSDLEHYL-GERGRRGHKLPRGLQ---------------------------------------------------
------------
>tr|A0A072N2S6|A0A072N2S6_9ALTE DNA topoisomerase 4 subunit A OS=Marinobacter sp. AK21 GN=parC PE=3 SV=1
DADLVSNDPVTVVLSEKGWVRAAKGHDIDA--------QGLNYKSGDRFALAAKGRNNQQAIFLDSTGRAYSLMAHSLPSARG--QGEPLTGRINPIAGA
TFAGVLMGE---PSRKVLLVTDGGYGFVTSLGEMVSKNRNGKAVVSVPKGAKIMAPVEIPEELYIGAVSNEGRMLVFPLSELPQLAK-GKGNKIISIPSA
EFVVALAVFAQDDQLEIRAGKRKMQFSDLEHYL-GERGRRGHKLPRGLQ---------------------------------------------------
------------
>tr|M7CQZ4|M7CQZ4_9ALTE DNA topoisomerase 4 subunit A OS=Marinobacter santoriniensis NKSG1 GN=parC PE=3 SV=1
EVDLVSNDPVTVVLSEKGWVRAAKGHDIEP--------EGLSYKAGDRFALAARGRNNQQAIFLDSTGRAYSLLAHTLPSARG--QGEPLTGRINPPSGA
TFSGLLLGE---PSGKVLLVTDGGYGFVTSMNDMISKNRNGKAVVSVPKGAKILSPVSVPEPLYLAAISNEGRMLVFPLSELPELAK-GKGNKIISIPSA
EYVVAVAVFAQDDQIEIRAGKRKMKFSDLEHYI-GERGRRGHKLPRGLQ---------------------------------------------------
------------
>tr|A0A0P7Z7T2|A0A0P7Z7T2_9ALTE DNA topoisomerase IV, A subunit OS=Marinobacter excellens HL-55 GN=parC PE=4 SV=1
ETDLVSNDPVTVVLSEKGWVRAAKGHDIDP--------TGLSYKGGDHFALAACGRNNQQAVFLDSTGRAYSLMAHSLPSARG--QGEPLTGRINPPSGA
TFSGLLMGE---PERKTLLVTDGGYGFVTSLNDMVGKNRAGKAVVSVPKGARIMPPVMIPVTLYLAAISNEGRMLVFPLNELPELAK-GKGNKIISIPSA
EYVVAVAVFGEEDQLEVKAGKRKLRFSDLEHYL-GERGRRGHKLPRGLQ---------------------------------------------------
------------
>tr|A0A0F9PSC7|A0A0F9PSC7_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_0807250 PE=3 SV=1
ENDLVSNDPVTVVLSDKGWVRAAKGHDIDP--------NGLSYKSGDRFALVAKGRNNQQTIFLDSTGRAYSLMAHSLPSARG--QGEPLTGRINPPSGA
SFSGLLMGD---PARKTLLVTDGGYGFVTSLNDMLSKNRNGKAVVSVPKGAQIMSPVVIPEGLYLGAITNEGRMLVFPLSELPELSK-GKGNKIISIPSA
EFVVAIAVFAEDDQLEIRAGKRKMQFSDLEHYL-GERGRRGHKLPRGLQ---------------------------------------------------
------------
>tr|A0A0F6KKV9|A0A0F6KKV9_AERHY DNA topoisomerase 4 subunit A OS=Aeromonas hydrophila GN=parC PE=3 SV=1
EKELTPSEPVTVILSDKGWVRAAKGHDVDV--------EGLSYKAGDNYLAHAHGRSNQQAVFLSTLGRTYSLEAHTLPSARS--QGEPLTGRFALGAGE
EVRHLVMGN---EGEPYLICSDAGYGFVCKYDDLIGKNKNGKALLTVPEGGLVMAPQKIGPTDLCMAISNEGRMLLFPLNTLPVLGK-GKGNKLISIPSA
EFVVMAAVIPQGQSVTLFAGKRKLKPSDLDYYR-GERGRRGAKLPRGLQ---------------------------------------------------
------------
>tr|A0A0F4QEY4|A0A0F4QEY4_9GAMM DNA gyrase subunit A OS=Halomonas sp. S2151 GN=gyrA PE=3 SV=1
-------HDTVLLFSNRGKVYWLKVYEMPAASRGSRGKPLVNLLPEESINAIMPVKPDCYIFFATARGTVKRTSLEQFSRPRS--VGL---IAIDLEEGD
RLVGAAIT---SGSDHAMLLSSNGKAIRFEESQVRAMRARGVRGMRLLDAE-VISLIIPQSQIYILTGSENGYGKRTRLEEFPLRGRGGQGVIAMQTSNG
A-MVAAMQVCSSDEMMLITDRGTLVRTRVEEVSISSRNTQGVTLIRLG-EA-EALVKTVRIQ--------------------------------------
------------
>tr|A0A0B5FMU8|A0A0B5FMU8_9DELT DNA gyrase subunit A OS=Geoalkalibacter subterraneus GN=gyrA PE=3 SV=1
-------HSNVLFFTDQGKVYWLKVHEIPQGGRASRGKAIVNLLNPEKVMTVLPVK-GKYILTATQNGIVKKTDLMAYSN-RA--GGI---IALTIDEGD
RLIAAR-T---DG-MDILLASRNGKSIRFHE--VRSMRARGVRGMALE--DLVIGMETVTEAATLVTVTENGYGKRTSLDEYRVQSRGGKGIITIKASNG
K-VVDIKLCED-SDLMFITDRGKVLRTSVGHLSIIGRNTQGVRLMVLEP-D-ERIVAVAKLA--------------------------------------
------------
>tr|S2LFH5|S2LFH5_9GAMM DNA gyrase subunit A OS=Halomonas anticariensis FP35 = DSM 16096 GN=gyrA PE=3 SV=1
-------HDTVLLFSNKGKVYWLKVYEMPNASRGSRGKPLVNLLPDESINAILPVHADSYIFFATAKGTVKRTSLDQFSRPRS--VGL---IAIDLEEGD
RLVGAAVT---SGNDHVMLLSSHGKAIRFEESNVRAMRARGVRGMKLLGAE-VISLIIPQSQIYILTASENGYGKRTRLEEFPLRGRGGQGVIAMQTSNG
A-MVAAMQVYGNDEMMLITDKGTLVRTRVEEVSVSSRNTQGVMLIRLG-EG-ESLVKTVRID--------------------------------------
------------
>tr|S7UU06|S7UU06_DESML DNA gyrase subunit A OS=Desulfococcus multivorans DSM 2059 GN=gyrA PE=3 SV=1
-------HHTFLFFTNQGKVYWCKVYEIPQAGRASKGRAIVNLLNAEKLTTVLAVP-GSYIMMATRQAVIKKTDIMAFSR-RA--GGI---IALALAPGD
ELIGTR-T---DG-NNVFLGSASGKSIRFHE--IRPTRARGVRGMTLA--DILVGMEVLSHGQTLFTATENGYGKRTLIDEYPIQRRGGKGVITIKTSNG
Q-VIAILLVAE-DELMLMTDSGKLIRMPVSGISVISRNTQGVKLMDLDI-E-ERVIGAARLA--------------------------------------
------------
>tr|A0A0F2R090|A0A0F2R090_9DELT DNA gyrase subunit A OS=Desulfatitalea sp. BRH_c12 GN=gyrA PE=3 SV=1
-------HHSFLFFTNRGKVYWCKVYDIPQAGRTGRGKAIVNLLNEEHMTTVLAVP-GHYVLMATKAGTVKKTDIMAFSR-RV--GGI---IALGLSEGD
ELIAAR-T---DG-QNVFLGSAMGKSIRFHE--IRPSRSHGVRGMRLD--DRLIGMEVVRFGQTLFAVTINGYGKRTSIDEYPVHGRGGKGVITIKTNNG
E-VVGLLAVQD-HDIMLVTDRGKIIRIPVSNISVISRNTQGVRLIGMES-G-ERVVSAASLA--------------------------------------
------------
>tr|A0A0E3RVS5|A0A0E3RVS5_METMZ DNA gyrase subunit A OS=Methanosarcina mazei C16 GN=gyrA PE=3 SV=1
-------HNYILFFTNRGRLYWQKVYEIPEGSRQSRGKAIVNLLEEEMVNAMISVE-DKYLFMATRAGTVKKTPLSEFRN-RR--AGI---IAVSLDEGD
ELVKVL-T---DG-QEIMMVSKKGKAIRFSE--VRPMRARGVRGMTLEP--DVVSLDLVDETTTLLTVTDNGFGKRTEYSQYPVHRRGGKGVITIVTNNG
F-VSNVKSVAD-DELMFTSAEGIIIRIPAKDISIQGRNTQGVRVMNIKSG--DKVGGMARIK--------------------------------------
------------
>tr|A3RYJ8|A3RYJ8_RALSL DNA gyrase subunit A OS=Ralstonia solanacearum UW551 GN=gyrA PE=3 SV=1
-------HDYILCFSNRGRLYWLKVWEVPQGSRNSRGRPIVNMFP-EKINVILPVK-QHFVFMATSKGTVKKTALTEFSNPRK--AGI---IAVDLDEGD
FLIGADIT---DGQHDVMLFSDAGKAVRFDENDVRPMRARGVRGMNLE--EGVIAMLVAPAAGSVLTATENGYGKRTPISEYTRHGRGTKGMIAIQTSNG
K-VVAAALVAPEDEIMLITTGGVLIRTRVDEIREMGRATQGVTLIAVG-EG-NKLSGLQRVV--------------------------------------
------------
>tr|A0A0A2WWA5|A0A0A2WWA5_THEFI DNA gyrase subunit A OS=Thermus filiformis GN=gyrA PE=3 SV=1
-------HDDLLVFTNRGWVYRVKVYDLPELGRQARGVHVRALL-EEEVAALRSVRKEGYLVFATERGLVKRTALSEYKNLGS--AGL---IAIKLLEED
RLVDVD-A---EEDGEVVLATREGQAIRFPL--VRATRSQGVTGIRFK---GRVVSLVVLSDPDLLAVSTKGFGKRTPLSEYPLQGRGGMGVITY--SVG
S-LAALLKVGAGADLLVLSKRGLAIRTPVKEIPRYSRATAGVRVMNLAE-G-DEVASAFVVK--------------------------------------
------------
>tr|K7QVY1|K7QVY1_THEOS DNA gyrase subunit A OS=Thermus oshimai JL-2 GN=gyrA PE=3 SV=1
-------HDDLLFFTGRGRVYRLKVYELPEMGRQARGVHVKSLL-EEEVAALLSVRGEGDLLFATEGGMVKRTPLKEYRNLGS--AGL---IAIRLHPED
RLIGVA-A---DPEDEVILATREGMAIRFPL--VRATRTQGVTGIRFK---DVVSLVAVKPMAELLAVSTRGYGKRTPLAEYPLQGRGGVGVITY--SVG
T-LAALLKVKGTEDLLVLSKRGLALRTPVAEIRTYSRATAGVRIMNLPE-D-DEIASAFVVE--------------------------------------
------------
>tr|A0A0N0ZND1|A0A0N0ZND1_THESC DNA gyrase subunit A OS=Thermus scotoductus GN=gyrA PE=3 SV=1
-------HEDLLLFTNRGRVYRLKVYELPEMGRQARGVHVKTLL-EEEVAALLSVRGEGYLVFATERGLVKRTALREYQNLGA--AGL---IAIRLLEGD
RLIGVA-S---DPEDEAILATEEGQAIRFAL--VRATRSQGVTGIRFK---DVVSLVTVKPMVDLLAVSTRGYGKRTPLAEYPLQGRGGMGVITY--SVG
R-LAALLKVRGTEDLLVLSKKGLAIRTPVADIRQYSRDTAGVKVMNLPE-D-DEVVSAFAVE--------------------------------------
------------
>tr|A0A0N0BLT6|A0A0N0BLT6_THEAQ DNA gyrase subunit A OS=Thermus aquaticus GN=gyrA PE=3 SV=1
-------HDDLLVFSNRGRVYRLKVYDLPEMGRQARGVHVKTLL-EEEVAALLAVRGEGYLVFATERGLVKRTALKEYANLGA--GGL---IAIRLLEGD
RLVGVA-S---DPEDEAILATAEGQAIRFPL--VRATRTQGVVGIRFK---DVVSLVTVKPMVDLLSVSTRGYGKRTPLSEYPPQGRGGMGVITY--SVG
R-LAALLKVRGTEDLLVLSKKGLTLRTPVAEIRQYSRATAGVKVMNLPE-E-DEIASAFVVE--------------------------------------
------------
>tr|Q72IZ1|Q72IZ1_THET2 DNA gyrase subunit A OS=Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) GN=gyrA PE=3 SV=1
-------HDDLLLFTNRGRVYRLKVYELPEMGRQARGVHVKSLL-EEEVAALLSVRQEGHLVFATERGLVKRTALKEYQNLGQ--AGL---IAIRLQEGD
RLVGVA-S---DPEDEAILATQEGQAIRFPL--VRATRTQGVIGVRFK---DVVSLVVVKPMVDLLSVSTRGYGKRTPLSEYPLQGRGGMGVITY--SVG
R-LAALLKVRGGEDLLVLSRRGLAIRTPVAEIRQYSRATAGVRVMNLPE-D-DEVASAFVVE--------------------------------------
------------
>tr|F2NCU3|F2NCU3_DESAR DNA gyrase subunit A OS=Desulfobacca acetoxidans (strain ATCC 700848 / DSM 11109 / ASRB2) GN=gyrA PE=3 SV=1
-------HNYFLVFSNLGRIYWLKVHEIPVGSPSARGKAIVNLLNSEKLTTILPIR-EHYLVMATKRGIIKKTELMNFSR-RS--GGL---IACTLDEGD
ELVSVA-T---DG-KEVFLGTSLGKIIRFAE--VRDMRARGVRGMTVA--DCIVGMEILSAEGAILTVTANGYGKRTRHEEYRLQKRGGSGLLALRITNG
P-VVGIIQVTD-DEIMLITDRGKIIRLPVTGISLIGRVTQGVKLIDTEP-E-ERVVSIARLA--------------------------------------
------------
>tr|D8FD24|D8FD24_9DELT DNA gyrase subunit A OS=delta proteobacterium NaphS2 GN=gyrA PE=3 SV=1
-------HDYFLFFTNKGRVYWKKVHEIPEGGRMSRGKAIVNLLDKERLATILPVR-GKYVVMATKMGFVKKTELKAYSH-RS--VGT---IGLKIREND
ELIAVR-S---SG-QDIFLTTKEGKSIRFKE--LRSMRAAGNIGIKME--NEVVGMETLGEGATILTVTENGFGKRTNREEYPTQARAGKGVITIKTSNG
L-VVYAYEVTQ-DELMIITGHGKIIRIRAADISVIGRNTQGVKLIDLGE-G-EKVVGVAKIM--------------------------------------
------------
>tr|K9ZWD9|K9ZWD9_DEIPD DNA gyrase subunit A OS=Deinococcus peraridilitoris (strain DSM 19664 / LMG 22246 / CIP 109416 / KR-200) GN=gyrA PE=3 SV=1
-------HDFLLFFTDQGRVFHEKIYDLPEVGRDAKGTYIKNLLP-ESIASVMSIKQEGSFVFATKRGMIKKTLIRDYANITS--AGL---IAINMMEGD
ELIGVG-V---KDGEHVVLATAEGQAMRFDA--VRDTRTQGVIGIRLR---KVVSMALVPSETELLAVSECGLGKRTPLSEYPAKGRGGQGVITL--TTG
N-LVTLAHVSGDEELMVLTEKGVVIRTRVEELRVSGRNSQGVKVMDIGK-G-DRVISAFPVK--------------------------------------
------------
>tr|B6WBH0|B6WBH0_9FIRM DNA gyrase subunit A OS=Anaerococcus hydrogenalis DSM 7454 GN=gyrA PE=3 SV=1
-------HESLLCFTNLGRVYSLKCYEIPE-SRQSRGQAIINLISSEKITDIMELS-KSQLVFQTENGKIKKTDAELFTNIQR--NGI---IAISLEDGD
RLVSIRQI---DKPCDIIVTTKKGMAIKFA---IRSMRARGVRAIRLG---KVVSMNIVE-EVYLVVVTANGFGKKTSFNNFNNQNRGGKGVRCHKITTK
D-VVATLPAN-DDDIMMVSLKGDMIRISTRDIST-GRNTLGVKLKNLENTE-DYIVSVTKYY--------------------------------------
------------
>tr|H3NQT7|H3NQT7_9FIRM DNA gyrase subunit A OS=Helcococcus kunzii ATCC 51366 GN=gyrA PE=3 SV=1
-------HSTILFFTNKGKVYKKRAFEIKE-KRQSKGQAIINILQIESISAVIAID-DKYIVLATRNGKIKRMSSSEFLNIRT--TGI---IAITLTEGD
ELIAAREV---QDDSKILMVTENGQSIIFE---VRPMRAQGVKGISLS---KVVDAAIID-NEYIFIVTEKGYGKKTLIKHYKAQKRSGKGVKTYKLTTG
K-IVSTKLVN-EDQVLLVSANSEVIRLNVKDIST-GRATQGVRLKKVRSDE-ENIVACAKYI--------------------------------------
------------
>tr|E3BS42|E3BS42_9LACO DNA gyrase subunit A OS=Lactobacillus iners LEAF 2053A-b GN=gyrA PE=3 SV=1
-------HDYLLFFTNKGKVYSKKSYEIPEYGRAAKGLPIINLVQEEKVQAVVKIATNKYLMFVTKYGIVKRISISEFTN-RR--SGL---IALNLREND
ELSNVL-T---DG-QNILIGTRLGYAVIFNE--VRTMRASGVRGIKLR---NVVGSSIVDDHSEVLVISEKGYGKRTLASEYPIKSRGCMGVKTANVTNG
P-LVGVTVVDS-EDLMLITDAGVIIRLEVDGVSQTGRATIGVRLIKLDQG--TKVASLTRVK--------------------------------------
------------
>sp|D5ECW5|GYRA_AMICL DNA gyrase subunit A OS=Aminobacterium colombiense (strain DSM 12261 / ALA-1) GN=gyrA PE=3 SV=1
-------HRDIYLFTSKGRVLALKGYVIPE-SKTGRGKLINRFVAEERVVTMHGRAGAKYAFFITLRGTAKRLDLSELENLTR--AGR---RVMGLDEGD
EISQIVLT---SGDDHLLIVTAQGQALRTHE--FRPMRARGVRGIRLR---YVIGCDVVAN-RWPLLLSENGFGKRTKYDEFSLRHRGGSGVIVM--STG
L-IVGCWSVAEGDEIVAITSRGRMIRLAVSESPVLGRTAMGSIMMRLDE-G-DTVATASVVS--------------------------------------
------------
>tr|D3L3I6|D3L3I6_9BACT DNA gyrase subunit A OS=Anaerobaculum hydrogeniformans ATCC BAA-1850 GN=gyrA PE=3 SV=1
-------HHDIFLFTSKGRVFAIKGYLLPE-PKNGKGKHVSSFFTEERVVAIKEDTGARFVFFATERGIAKRLDVSELANLTR--AGR---RVITLDDGD
FIARVRFT---SGEDELLFVSAKGQALRTSE--FRPMRARGVRAIRLS---VLVGCEPLQE-MAILFISEKGVGKRTSFDEFPLHHRGGSGVRAM--STG
S-LVGAWSVTEDDEVMIVTSKGRVTRIAVRNVPVLSRTATGSILVRLDQ-G-DSVADITIVR--------------------------------------
------------
>tr|I4BU81|I4BU81_ANAMD DNA gyrase subunit A OS=Anaerobaculum mobile (strain ATCC BAA-54 / DSM 13181 / NGA) GN=gyrA PE=3 SV=1
-------HHDIFLFTNKGRVFAIKGYLLPE-PKNGKGKHVSSFFTEERVVAIKDDTGAKFVLFATKNGIAKRVDVRELGNLTR--AGR---RIINLDEGD
EIARVRFT---SGSDDLLFVSAKGQALRTSE--FRPMRARGVRAIRLS---ILVGCEPLRE-TMILLISEKGVGKRTSSDEFPLHHRGGSGVRAM--STG
L-IVGAWSVTEDDELMIVTSKGRVTRITVKDVPVLSRTATGNILVRLDQ-G-DEVADVTVIR--------------------------------------
------------
>tr|G7V794|G7V794_THELD DNA gyrase subunit A OS=Thermovirga lienii (strain ATCC BAA-1197 / DSM 17291 / Cas60314) GN=gyrA PE=3 SV=1
-------HRDIFLFTSRGRVYAIKGHVLPE-PKVGKGRLVSNYINAESIVAVADSKGAKYVFFITEKGTAKRMPAEELVNLTR--AGR---IVLSLGEGD
KIARVRFT---SGEDELLFVTAHGKALRVKE--FRPMRAKGVRGIRLA---IVVGCDVIKE-KQTFLVSAKGVGKRTEYSEFTCHHRGSGGVKAM--STG
L-LVGSWSLAPEDEVMLMTSMGRVIRLDAKDISILSRVATGYRVVKLEE-G-DEVADVSVIH--------------------------------------
------------
>tr|H0UPS6|H0UPS6_9BACT DNA gyrase subunit A OS=Thermanaerovibrio velox DSM 12556 GN=gyrA PE=3 SV=1
-------HRTLYLFTDRGRVFALKCLALPE-PKSGRGKHVGSFISEESVVTFRDSVRAKFVFLLTRMGLAKRLPVAELEGITR--AGR---RILGLEDGD
TIARVRFT---GGDDELLLTTAKGQTLRVSE--FRPQRAKGVKAIKLE---AVVGCDVIIP-RQVLFISQLGLGKRTPYEEFTTHHRGGMGVRAM--NTG
D-LVGAWGVAEDDELMVVTSRGRVIRMAAREISTLSRMATGSTVVRLDE-G-DSVADVTVIR--------------------------------------
------------
>tr|E3CZ44|E3CZ44_9BACT DNA gyrase subunit A OS=Aminomonas paucivorans DSM 12260 GN=gyrA PE=3 SV=1
-------HRTLYLFTSRGRVFAIRGFTLPE-PKTGKGKHVSTFVSEERVVTLRDSRGARFVFFVTQRGVAKRLPVTELDGINR--AGR---RILGLAPED
TIARVRFT---GGEDELLLTTAQGQTLRVPE--FRPQRAHGVRGVRLD---LVVGCDVIEP-RQVLFISERGIGKRTPYDEFTAHHRGGGGVRAM--VTG
D-LVGAWGVREDDELVVISAKGRMVRLLAGEISSLGRAATGYKVVRLDE-G-DEVADVSIIR--------------------------------------
------------
>tr|D1B8A6|D1B8A6_THEAS DNA gyrase subunit A OS=Thermanaerovibrio acidaminovorans (strain ATCC 49978 / DSM 6589 / Su883) GN=gyrA PE=3 SV=1
-------HRSLYLFTDRGRVFSLKCLAIPE-PKSGRGKHVSTFISEESVVTFRDSAGARFVFLVTKMGLAKRLPVGELEGITR--AGR---RILGLEEDD
TIARVRFT---GGEDQLLLTTAKGQTLRVSE--FRPQRAKGVRGIKLD---LVVGCDVIMP-RQVLFISQLGMGKRTRYEEFTVHHRGGMGVRAM--GTG
H-LVGAWGVADDDEIMVITSRGRVVRFSARDVSSLSRSAMGLTLVRLDE-G-DQVADVTVIR--------------------------------------
------------
>tr|A0A011AA33|A0A011AA33_9BACT DNA gyrase subunit A OS=Cloacibacillus evryensis DSM 19522 GN=gyrA PE=3 SV=1
-------HRTLYLFTNKGRVFGVRGFSLPE-PKTGKGKLVGTIITKEKVVAIKDSLGTKFIFFVTKQGTAKRLPVEELDGLTR--AGR---RVLGISEGD
DISRVRFT---SGTDDLLLTTALGQTLRVNE--FRPLRAQGVRGIRLD---SVVGCDVVSD-RHVLFISERGIGKRTSYDEFTQHHRAGYGVRAM--STG
D-LVGAWGVQDDEEIIVISSKGRMVRIGAQEISTLSRTATGYMIVTLDE-G-DTVADISIVR--------------------------------------
------------
>tr|A0A0F7P9Z6|A0A0F7P9Z6_9EURY DNA gyrase subunit A OS=Halanaeroarchaeum sulfurireducens GN=gyrA PE=3 SV=1
-------HDHLLCFTDQGQVYRLKVYQIPEMSRTARGTSAVNLL-DEEITAVVATDEDEYLTMATRNGYVKRTGAEEFENILS--TGI---IAISLADGD
ELVDVE-T---NGASDVVLGTEKGMAIRFDE--VRSMRARGVWGIELE---DVAGVSAIREDRTLLTVTRRGFGKRTPLSEYRRQSRNGKGLVDI--DNG
W-VAAIEAVAETDHVIAMSDDGQIIRMPVAEISTVGRNTKGVRVMAIDA-D-DQLAGISVFP--------------------------------------
------------
>tr|A0A073JTB3|A0A073JTB3_9BACI DNA gyrase subunit A OS=Bacillus manliponensis GN=gyrA PE=3 SV=1
-------HDHILFFTNKGKVYRTKGYEIPEYSRTAKGIPIINLLEKEWVNAIIPIRDDQFLFFTTKHGIAKRTPLSSFAN-RN--NGL---IAISLREED
ELISVR-T---TG-KDMIVGTSNGMLIRFHE--VRSMRAAGVKAITLG--DDVVGMEIVEENMDVLIVTKNGYGKRTAIEEYRLQSRGGKGLKTCNITNG
K-LIAVKTVYE-EDIMLITAAGVLIRMPVDQISQMGRNTQGVRLIRLED-D-QEVATVAKAQ--------------------------------------
------------
>tr|J3JPL4|J3JPL4_STRRT DNA gyrase subunit A OS=Streptococcus ratti FA-1 = DSM 20564 GN=gyrA PE=3 SV=1
-------HDSMLFFTNQGRVYRLKGYEIPEYGRTAKGLPVVNLLKDETIQTIINVN-DKYLFFTTRQGLVKRTSVSAFGN-RQ--NGL---KALNLRDGD
ELINVL-T---DG-NDIIIGTRQGYSVRFNE--VRNMRATGVKGVNLR---QVIGAAHIVDNQDVLTITEKGYGKQTPANQYPTKGRGGKGIKTANITNG
P-LAGLVTVND-EDIMVITDTGVIIRTSVANISQTGRSAMGVKVMRLDKQ--AKIVTFALVK--------------------------------------
------------
>tr|G5JVC0|G5JVC0_9STRE DNA gyrase subunit A OS=Streptococcus macacae NCTC 11558 GN=gyrA PE=3 SV=1
-------HDAMLFFTNRGRVYRLKGYEIPEYGRTAKGLPIVNLLKEETIQTIINVK-DKYLFFTTKEGIVKRTTVSAFAN-RQ--NGL---KALNLRGGD
ELINVL-T---NG-EDIIIGTRSGYSVRFKE--VRNMRATGVKGVSLR---KVIGAAAVSDSQEVLTITEKGYGKQTAASEYPTKGRGGKGIKTVNITNG
Q-LAGLVTVDD-EDIMLITNTGVIIRTSVANISQTGRSAMGVKVMRLDKE--AKIVTFALVK--------------------------------------
------------
>tr|V6Z2I3|V6Z2I3_STRAG DNA gyrase subunit A OS=Streptococcus agalactiae LMG 14747 GN=gyrA PE=3 SV=1
-------HDILLFFTNLGRVYKLKGYEIPEYGRTAKGLPVVNLLKDEFIQTMINAR-DHYFFFTTYAGVVKRVPTSEFDN-RQ--NGL---KALTLKDND
QLINVL-T---TG-DDIIIGTSAGYSVRFNE--VRTMRAAGVRGVKLR---EVVGASTITDDQEVLIVTEKGYGKRTSAEEYPTKGRGGKGIKTANITNG
A-LAGLVTVSD-EDVMLITNKGVVIRTNVSNISQTGRSTMGVRLMRLDET--AKLVTFALVD--------------------------------------
------------
>tr|A0A096BH59|A0A096BH59_9CLOT DNA gyrase subunit A OS=Caloranaerobacter azorensis H53214 GN=gyrA PE=3 SV=1
-------HDNILFFTNKGKVYKLRAFEIPEAKRQAKGTAIINLLNIEKITAVIPIK-EDYLVFATKKGLIKKTGLNEFDN-RK--NGL---IAINLREED
ELIEVR-T---NG-DELILVTAHGMSIRFSE--VRNMRAMGVKAITLN---DLVAMDLIKEDNDLLVITEKGYGKRTQISEYRSQSRGGKGIKTYNVRTG
N-IVGAKVVSN-DEVMLISVSGTIIRLKVSDISQMGRSTQGVTLMKVSEN--DRVVSIAKVA--------------------------------------
------------
>tr|K0AWF9|K0AWF9_CLOA9 DNA gyrase subunit A OS=Clostridium acidurici (strain ATCC 7906 / DSM 604 / KCTC 5404 / 9a) GN=gyrA PE=3 SV=1
-------HDNLLFFTNQGKVYTMKAYEIPEAKRQARGMAIINLLQPEKITAVIPIR-DNYLILVTKKGITKKLRLNELQN-RK--NGL---IAISLKEED
ELIGVR-T---EG-DNVILVTSNGMSITFNE--VRDMRAMGVKAITLN---GLVGMDLVKPNKELLVISEFGYGKRTSLDEYRIQSRGGKGIKTYNIKTG
K-IISAGVVED-DDILIVSLGGTIIRLNVSDISQMGRSTQGVRLMKMAKD--DKVVSVAKVL--------------------------------------
------------
>tr|Q0W7S4|Q0W7S4_METAR DNA gyrase subunit A OS=Methanocella arvoryzae (strain DSM 22066 / NBRC 105507 / MRE50) GN=gyrA PE=3 SV=1
-------HDNILFFSNKGKVYSLKVYEIPPASRQARGKAIINLINPEAINAMIPIK-QHFLVMCTREGTIKKTALSAFQN-RS--TGI---IAIGLESGD
ELISVK-T---NG-QEVLIATRNGKCNRFSE--VRTMRAMGVIGIRLT--DKVIAMEIVSP-QSVLTICENGFGKRTPIEEYTAHHRGGQGMINIKTTNG
A-VVAVISVMD-DQIVIASKEGMMTRMNVTDIPEIGRNTQGVRVMKMRPE--DSVVAVARLV--------------------------------------
------------
>tr|R2N137|R2N137_ENTMU DNA gyrase subunit A OS=Enterococcus mundtii ATCC 882 GN=gyrA PE=3 SV=1
-------HDTLLFFTNNGKVYRAKGYEIPEYGRTAKGIPIINLLGDEKIQAIIAVTEGHYLFFTTRQGTVKRTTVTAFAN-RS--NGL---IAIGLKEND
ELVNVL-T---DG-SNIIIGTHDGYSVTFAE--VRDMRASGVRGVRLR---DVVGAALMNDDHEVLIITEKGYGKRTKVSEYPVKGRGGKGIKTANITNG
P-LAGLTTVTE-EDIMLITDKGVIIRFNVSTVSQTGRATLGVRLIKMEAE--TKVVTMAAVE--------------------------------------
------------
>tr|S4DHB0|S4DHB0_ENTFL DNA gyrase subunit A OS=Enterococcus faecalis 13-SD-W-01 GN=gyrA PE=3 SV=1
-------HDTLLFFTNNGKVYRAKGYEIPEYGRTAKGIPVINLLGDENIQAIISVSEGHYLFFTTRLGTVKRTSVTAFSN-RS--NGL---IAIGLKDED
ELVNVL-T---DG-SNIIIGTHDGYSATFKE--VRDMRASGVRGIRLR---NVVGAALMKEDREVLVITEKGYGKRTKVSEYPVKGRGGKGIKTANITNG
P-LAGLTTVTD-EDIMLITDKGVIIRFNAATVSQTGRSTLGVRLMKMENE--TKVVTMATVE--------------------------------------
------------
>tr|A0A0M0L5H4|A0A0M0L5H4_9BACI DNA gyrase subunit A OS=Bacillus koreensis GN=gyrA PE=3 SV=1
-------HDTILYFTNKGKVYRTKGYEIPEFSRTAKGLPIINLLEKEWVNAIIPVEDDAYLFFTTKQGVSKRTPLSSFEN-RT--SGL---IALGLREED
ELISVK-T---DG-KEILIGTQNGMLIRFPE--VRSMRATGVKGITLA--DDVVGMEISDDESDILIVTRNGYGKRTKTSEYRIQSRGGKGLRTCNVTNG
K-IVSLKTVTE-EDIMLITVSGVLIRVATKDVSQMGRNTQGVKLIRLGD-E-EFVSTVAKVE--------------------------------------
------------
>tr|E0P0I5|E0P0I5_9FIRM DNA gyrase subunit A OS=Selenomonas sp. oral taxon 149 str. 67H29BP GN=gyrA PE=3 SV=1
-------HHDILFFTNRGRAFVLKSYEIPESGRQAKGTAIVNLLANERITAVIQVK-DRYLFLGTKHGVVKKTPLSEFGN-RK--NGL---RAVNLDEDD
ELIGVK-T---DG-NRIMLGTRGGKAITFPE--VRSMRARGVRGITLA---GVVAMDVLRSDSEVLTVTEGGYGKRTTASEYRTQTRGGKGLINMKVTTG
P-VVGIRVVRN-QELMLITTEGIVIRTSVDEISLISRNTQGVKLMTIAES--DRVASMATMN--------------------------------------
------------
>tr|C9KLW4|C9KLW4_9FIRM DNA gyrase subunit A OS=Mitsuokella multacida DSM 20544 GN=gyrA PE=3 SV=1
-------HHTILFFTNRGRVYHLKAYEIAEASRAAKGTAIINLLQKEKITAVIQVK-DAYLFMATKKGIVKKTSLVEFKN-HK--GGL---NAINLDDDD
ELIGVK-T---DG-RDMILGTKWGMAIVFGE--VRAMRARGVKGISLN---GVIGMDTLSPNAEVLTVTAEGYGKRTETSEYRAQNRGGKGLINLKVTTG
D-VIGLRVVHD-QELMLITTEGIVIRTNISDISVISRNTQGVKLMSTGEN--DIVASMAVMD--------------------------------------
------------
>tr|A0A0B2JMZ4|A0A0B2JMZ4_9FIRM DNA gyrase subunit A OS=Anaerovibrio lipolyticus GN=gyrA PE=3 SV=1
-------HHTILFYTNKGRVYYLKAYQIAEASRTAKGTALINLLKKEKVSAVIQVR-DKYLFMATKMGVVKRVSLSDFNT-RK--IGV---IAISLQEDD
ELIGVK-T---NG-QKIMLGTKNGMAIAFEE--VRVMRARGVKGIRLT---GVVAMDSLKEDADVLTVTECGLGKRTTIDQYTVQHRGGKGLINLKVTTG
K-VIGMAVVQD-HELLLITEGGVVLRTSISGISQIGRNTQGVIIMKPSEG--DKVSSMATLL--------------------------------------
------------
>tr|C9LYV0|C9LYV0_SELS3 DNA gyrase subunit A OS=Selenomonas sputigena (strain ATCC 35185 / DSM 20758 / VPI D19B-28) GN=gyrA PE=3 SV=1
-------HHTILFFTNRGRVYCLKAYEINEASRQAKGTAIINLLQSEKITAVIQVK-ERYLFMATKKGIVKKTSLSEFQS-RR--GGL---NAINLDEDD
DLIGVK-T---DG-KHVILGTAGGMAVAFAE--VRSMRARGVKGINLK---GVVGMDNLARNAEVLTITAEGYGKRTATSEYRLQTRGGKGLINMKVTTG
A-VIGLKVVRG-QELILITTDGIVIRTKVDEISVISRNTQGVKVVRLGEG--DKAASFAAME--------------------------------------
------------
>tr|U2UKI9|U2UKI9_9FIRM DNA gyrase subunit A OS=Mitsuokella sp. oral taxon 131 str. W9106 GN=gyrA PE=3 SV=1
-------HHTILFFTNRGRVYHLKAYEIAEASRAAKGTAIINLLPAESITAIIQVK-DNYLFMATKKGVVKKTSLIEFKN-HK--GGL---NAIHLDDDD
ELIGVR-T---NG-HDVILGTKWGMAILFPE--VRAIRGRGVRGIRLS---GVIAMDTLMPNADVLTVTAEGYGKRTQRDEYRTQTRGGKGIINLKVTTG
D-VVGLRVVRD-QELMLITTEGIVIRTNIGDISRISRNTQGVKLMTTAKG--DTVASMAVMD--------------------------------------
------------
>tr|I0GLV4|I0GLV4_SELRL DNA gyrase subunit A OS=Selenomonas ruminantium subsp. lactilytica (strain NBRC 103574 / TAM6421) GN=gyrA PE=3 SV=1
-------HHTILFFTTRGRVYSLKAYEIAESSRTAKGTAIINLLQQEKITAVIQVK-DRYLFMATRKGIVKKTSLSEFSN-RK--NGL---NAINLDDDD
DLMGVK-T---DG-SYLMLGTKLGKAIAFSE--VRAMRARGVKGITLS---GVVGMDILVRNAEVLTVTECGYGKRTSTDEYRAQTRGGKGLINMKVTTG
Y-VVGIKVVRE-HELMLITTDGIVIRTNVNDISVISRNTQGVKLMTTAEN--DKVASMATLE--------------------------------------
------------
>tr|G5GNI0|G5GNI0_9FIRM DNA gyrase subunit A OS=Selenomonas infelix ATCC 43532 GN=gyrA PE=3 SV=1
-------HHDILFFTNRGRAFVLKAYEIPESGRQAKGTAIVNLLASERITAVIQIK-DRFLFLATKRGVVKKTPLAEFAN-RK--SGL---RAVNLDEDD
ELIGVK-T---DG-NRIMLGTRHGKAIAFPE--VRSMRTRGVRGINLS---GVVAMDILKQGSEVLTVTEGGYGKRTTAEEYRTQTRGGKGLINMKVTTG
P-VVGIRVVRN-QELMLITTDGLVIRTMVDEISLISRNTQGVKLMTLGES--DRVASMATMN--------------------------------------
------------
>tr|G5H2R3|G5H2R3_9FIRM DNA gyrase subunit A OS=Selenomonas noxia F0398 GN=gyrA PE=3 SV=1
-------HHDILFFTNRGRVFVLKAYEIPESGRQAKGTAIINLLAAERITAVIQVR-DRFLFLGTKRGVVKKTPLAEFAN-RK--SGL---KAVNLDEED
ELIGVK-T---DG-NRIMLGTRLGKAIAFPE--VRSMRTRGVRGIMLA---GVVAMDILKSDSEVLTVTEGGYGKRTAAGEYRTQTRGGKGLINMKVTTG
P-VVGIRVVRD-QELMLITTEGIVIRTSVNEISRISRNTQGVRLMTIAEN--DRVASMATMN--------------------------------------
------------
>tr|A0A0J8H0P0|A0A0J8H0P0_9ENTE DNA gyrase subunit A OS=Melissococcus plutonius GN=gyrA PE=3 SV=1
-------HDTLLFFTNNGKVYRAKGYEVPEYGRTAKGIPIINLLGDETVQTIISVTEGHYLFFTTKNGTVKRTAVTAFSN-RS--NGL---IAIGLKEDD
ELVNVI-T---SG-QNIIIGTHTGYSTTFKE--VRDMRASGVRGIRLR---NVVGASLLDENTEVLVITENGYGKRTKAIEYPVKGRGGKGIKTANITNG
P-LAGLATVRD-EDILLITNKGIIIRFNAGSVSQTGRSTLGVRLIRMEET--AKVVTMAVID--------------------------------------
------------
>tr|R5I455|R5I455_9BACT DNA gyrase subunit A OS=Alistipes sp. CAG:831 GN=gyrA PE=3 SV=1
-------HSTMLFFTDKGKCYWLKVYEIPEGTKASKGRAIQNVISADHVCAYLNVGNSHYIVMATKRGVVKKTLLEAYSR-RQ--KGV---NAITIKDGD
GLLEAVLT---DGNNEILLAARKGKCVRFH---ARSIRASGVRGISIE---DVIGMVCAARQGNIMVVSANGYGKRSLLE-YRVTSRGAKGVKTLNITTG
E-LIAIKMVT-ENDLMIINKSGITIRVPVSDIRVAGRATQGVRLINLRE-G-DTIAAVCVVN--------------------------------------
------------
>tr|K1Y4V5|K1Y4V5_9BACT DNA gyrase subunit A OS=uncultured bacterium (gcode 4) GN=gyrA PE=3 SV=1
-------HSTMLFFTQKGRCFWLKVYEIPEGSKASKGRAIQNVLNQDKVCAYINVRNNNFIVLATKKGTVKKTSLEAYSR-RV--NGV---NAITIREND
ELLEAVLT---NGNSEILLAARNGKCVRFN---VRAIRASGVRGINIGD--DVIGMICVDYNKHILVVSENGYGKRSNLDDYRVTNRGAKGVKTINITTG
S-LIAIKDVT-ENDLMIINKSGITIRVAASDIRVVGRATQGVRLINIRE-G-DMIAAVCRVN--------------------------------------
------------
>tr|G4L3L6|G4L3L6_TETHN DNA gyrase subunit A OS=Tetragenococcus halophilus (strain DSM 20338 / JCM 20259 / NCIMB 9735 / NBRC 12172) GN=gyrA PE=3 SV=1
-------HDNLLFFTNAGKVYKAKGYEVPEYGRTAKGIPVINFLGNERIQTIIALPERKYLFFTTKYGVVKRTSVESFKN-RS--NGL---IAIGLKEDD
ELVNVL-T---SG-DVVIIGTHNGYSVTFKE--VRDMRASGVRGIRLR---EVIGASVIKEDDEVLVITEKGYGKRTSEDQYPVKGRGGKGIKTANITNG
P-LAGLTTVSN-EDVMLITDRGVIIRFHVDDISQTSRATLGVRLMKMEDD--AKVVTMTTVD--------------------------------------
------------
>tr|V6Q9G2|V6Q9G2_9ENTE DNA gyrase subunit A OS=Vagococcus lutrae LBD1 GN=gyrA PE=3 SV=1
-------HDTLLFFTNTGKVYRAKGYEIPEYGRTAKGIPIINLLGDEKIQSVISVEENSYLFFTTKHGTVKRTTTEAFAN-RS--NGL---IAIGLRDGD
EVMNVT-T---NG-QIIIIGTHLGYSVTFKE--VRDMRAAGVRGVRLR---GVVGMSTLTENNEVLILTENGYGKRTDSSEYPVKGRGGKGIKTANITNG
P-LVALTTVED-EDVLVITDQGVIIRFDVDSVSQTGRATQGVRLIRLEEG--SKVATMAIIE--------------------------------------
------------
>tr|R2ST25|R2ST25_9ENTE DNA gyrase subunit A OS=Enterococcus pallens ATCC BAA-351 GN=gyrA PE=3 SV=1
-------HDTLLFFTNTGRVYRAKGYEIPEYGRTAKGIPIINLLGDETIQAVIAVTDGQFLFFVTKNGIVKRTTVTAFSN-RS--NGL---IAIGLKEND
ELVNVL-T---EG-ETIILGTHNGYSVTFAE--VRDMRASGVRGVRLR---DVIGSAVLKDDQEVLVITEKGYGKRTKAADYPVKGRGGKGIKTANITNG
Q-LAGLATVND-EDILLITDKGVIIRFNVASVSQTGRATLGVRLMKMEEN--TKVVTMAVVE--------------------------------------
------------
>tr|E6H6H4|E6H6H4_ENTFL DNA gyrase subunit A OS=Enterococcus faecalis TX0309B GN=gyrA PE=3 SV=1
-------HDTLLFFTNTGKVYRAKGYEIPEYGRTAKGIPVINLLGDEKIQAIISVEAGKYLFFTTLKGTVKRTAVTAFSN-RS--NGL---IAISLKEDD
ELVNVV-T---NG-QKMIIGTHAGYSVTFDE--VRDMRASGVRGIRLR---NVVGAAILDENKEVLVITENGYGKRTKASEYPVKGRGGKGIKTANITNG
P-LAGLTTVND-EDILLITNKGVIIRFNVDSVSQTGRATLGVRLMRMEDG--AKVVTMAVVE--------------------------------------
------------
>tr|A0A0I9WNI8|A0A0I9WNI8_9ENTE DNA gyrase subunit A OS=Enterococcus cecorum GN=gyrA PE=3 SV=1
-------HDTLLFFTNQGKVYKAKGYEIPEYGRAAKGIPVINLLGDELIQAIIPVSAGRYLFFTTKYGVVKRTEVTAFSN-RS--NGL---IAIGLKEGD
ELVNIV-T---NG-NTIIIGTHDGYSVRFEE--VRDMRAAGVRGIKLR---GVVGSSVISDNQEVLVITENGYGKRTAASEYPVKGRGGKGIKTANITNG
P-LAGLTTVDS-EDILLITDKGVIIRFNVDSVSQTGRATLGVRLMKMEED--TKVVTMATVE--------------------------------------
------------
>tr|A0A0R2GRK5|A0A0R2GRK5_9LACO DNA topoisomerase (ATP-hydrolyzing) subunit A OS=Lactobacillus acetotolerans DSM 20749 = JCM 3825 GN=FC77_GL001312 PE=4 SV=1
-------HDSLLFFTNKGKVYSKKAFEIPEYGRTAQGLPVVNLLREEKIQTIINIPKDNYLFFITKMGTVKRTHVSAFSN-RN--SGL---IALTLRDGD
ELNNVL-T---DG-QNILIGTHLGYAVTFNE--VRAMRAAGVRGIKLR---HVVGSGVIKPNDEVLVISEKGYGKRTAAKEYPVKGRGGKGIKTSNITNG
P-LAGVKVIDT-QDIMVITTNGIMIRFKIGDVSQTGRSTMGVRLIKVSGK--SKVASLAIVP--------------------------------------
------------
>tr|A0A0R2JM96|A0A0R2JM96_9LACO DNA gyrase subunit A OS=Lactobacillus lindneri DSM 20690 = JCM 11027 GN=IV52_GL001407 PE=4 SV=1
-------HDLLLFFTNSGKVYSMKAYEVPEYGRSAKGIPIVNLIHGEKIQTVLDISDDKYLFFTTKLGTVKRTPLNEFVN-RN--NGL---KSINLRDQD
EVINVS-V---DD-QNMIIGTHLGYAVSFKV--VRTMRATGVRGVRLR---DVIGAAILAPDSDVFVISEKGYGKRTPADQYAIKGRGGKGIKTSNISNG
P-LVGLGVIND-EDIMLITDQGVMIRFAAGNVSETGRATLGVHLIRVDDG--SKVATMAIVQ--------------------------------------
------------
>tr|W9EEN3|W9EEN3_9LACO DNA gyrase subunit A OS=Lactobacillus florum 8D GN=gyrA PE=3 SV=1
-------HDSLLFFTNKGKVYRLKAYEVPEYGRSAKGLPIVNLLHDEKIQTILNVAQPDQLFFTTKMGTVKRTALAEFVN-RN--NGL---KAINLREHD
EVIKVL-V---KS-QNMILATRQGYAVSFQV--VRLMRATGVRGVRLR---NVIGADRLIPGQQVFVISENGFGKQTPVAQYPIKGRGGKGIKTAQIKNG
P-LVGMNVVAD-EDVMLITTQGVLIRMAIADVSQTGRATLGVHLIRLDDG--SKVATMTIVA--------------------------------------
------------
>tr|A0A0C1M7K8|A0A0C1M7K8_9LACO DNA gyrase subunit A OS=Lactobacillus fructivorans GN=gyrA PE=3 SV=1
-------HDRLLFFTNAGKVYSMKAYEVPEYGRAAKGIPIVNLLNGEKIQTVISISQDKYLFFTTKQGTVKRTPVSDFLN-RK--NGL---KAIHLHDGD
EVIGVS-V---DN-DNMIIGTHLGYAVSFKA--VRSMRASGVRGVRLR---EVVGAAILTPDSDVFVISENGYGKRTKAADYPIKGRGGKGIKTSNVTNG
P-LVGLSTVTD-EDIMLITNMGVMIRFAVNNVSETGRATLGVHLIRVDDD--AKVATMAVVA--------------------------------------
------------
>tr|G2KTA0|G2KTA0_LACSM DNA gyrase subunit A OS=Lactobacillus sanfranciscensis (strain TMW 1.1304) GN=gyrA PE=3 SV=1
-------HDLLLFFTNAGKVYSMKVYEVPEYGRSAKGLPIVNLINGEKIQTVLRVDEHKYLFFTTKLGTVKRTPIDEFTN-RN--NGL---KAINLHDDD
ELIKVS-V---DG-QNMIIGTHLGYAVSFKV--VRSMRASGVRGVRLR---DVIGASILTPGSDVFVISENGYGKRTPVNQYPIKGRGGKGIKTSNVTNG
P-LVGLGVVND-EDIMLITDQGVMIRFAAGNVSETGRSTLGVHLIRVADD--STVATMAIVQ--------------------------------------
------------
>tr|U5CJA7|U5CJA7_9PORP DNA gyrase subunit A OS=Coprobacter fastidiosus NSB1 GN=gyrA PE=3 SV=1
-------HNYMLFFTQKGKCYWLKVYEIPEGAKNSKGRAIQNMLNADKVNAFIRVKMSHNLLFCTRKGVIKKTKLEAYSR-RQ--NGV---NAITIREDD
QVIQVRLT---TGDSQIIMANKHGRAIRFH---VREMRATGVRGMTLDTG-DVIGMICIKDKETVMVVSEQGYGKRSEI-DYRITNRGGKGVKTLNITTG
N-LVAIKSVT-ENDLVIINKSGITLRMKVADVRIMGRATQGVRLINLEKRN-DEIASVCKVL--------------------------------------
------------
>tr|R7HQC1|R7HQC1_9BACT DNA gyrase subunit A OS=Prevotella sp. CAG:279 GN=gyrA PE=3 SV=1
-------HNYMLFFTQQGRCYWMKVYDIPEGTKTSKGRAIQNLLNSDKVKAFVNVKNSHYLMFCTKNGVVKKTRLEAYSR-RQ--NGV---NAIVIREGD
ELLQVRMT---NGNEEVLLANRNGRAIRFN---VREMRSAGVKGMTLDG--DVVGMITMPFEKTVMVVSEQGYGKRSVLDDYRVTNRGGKGVKTINVTTG
R-LVDIKDVD-TKDLVIINKSGITIRLKVADVRVMGRATQGVRLINLEKRN-DEIASVCVVD--------------------------------------
------------
>tr|A0A0K8R0A3|A0A0K8R0A3_9BACT DNA gyrase subunit A OS=Bacteroidales bacterium 6E GN=gyrA PE=3 SV=1
-------HNTLLLFTKNGKCYWLKVWQIPEGTRTSKGRAIQNVLNPDKVLAYIKVKNNNYIILATKQGIIKKTTLEAYSR-RV--NGV---NAISVREGD
ELIEARRT---SGNHEIMIAVRSGKAIRFN---VRPIRSMGVRGITLGE--DVIGMICVND-DDVLVLSENGYGKRSSLADYRITNRGGKGVKTINITTG
N-LISIKNVG-DNDLMIITQNGLTIRVPVKTIRVMGRAAQGVRIINLKQ-G-DSIASVAKVR--------------------------------------
------------
>tr|R5NQ46|R5NQ46_9PORP DNA gyrase subunit A OS=Odoribacter sp. CAG:788 GN=gyrA PE=3 SV=1
-------HNTMLFFTEKGRCFWLKVYEIPEGTKQSKGRAIQNLLNPDKVKAYINLLNSNYIVLCSKKGIIKKTTLEAYSR-RQ--NGV---NAITIKEGD
QLLEAKLT---NGDNDIMLAVKSGKAIRFP---VRPMRAAGVKAIKLKE--DVIGMICVEP-ADILVVSENGFGKRSAISDYRITNRGGQGVKTINLTTG
N-LIALLDVT-EDNLMIITKSGLTIRMEVASLRVMGRNTQGVKLINLRS-D-DAIAAVAKVS--------------------------------------
------------
>tr|X5E334|X5E334_9BACT DNA gyrase subunit A OS=Draconibacterium orientale GN=gyrA PE=3 SV=1
-------HNTLLLFTEKGKCYWLKVYEIPEGTRASKGRAIQNMLNPDQVLAFIKVKNNNYIILATKKGIIKKTTLEAYSR-RQ--NGV---NAITIKEGD
QLLEARLT---NGKSEVMLAVRSGKAIRFN---VRAIRASGVRGITLGE--DVIGMVCVMD-EDILVVAEKGYGKRSKIDDYRITNRGGKGVKTLNITTG
E-LVAIKSVS-DNDLMIITQKGITIRLAVNTISVLGRATQGVRVINLRE-D-DRIASVARIA--------------------------------------
------------
>tr|R6F3V1|R6F3V1_9PORP DNA gyrase subunit A OS=Odoribacter splanchnicus CAG:14 GN=gyrA PE=3 SV=1
-------HNTMLFFTEKGKCFWLKVYEIPEGTKQSKGRALQNLLNPDKVKAYINLLNSNYIVLCTKKGIIKKTTLEAYSR-RQ--NGV---NAITIKEGD
QLLEAKLT---NGENDIMIAVKSGKAIRFP---VRPMRASGVRGIWMED--DAIGMVCVEP-ANILVVSENGFGKRSAIEDYRITNRGGKGVKTINMTTG
N-LIALIDVT-EDNLMIINRSGLTIRLEVSSLRVMGRNTQGVKLINLRN-E-DSIAAVAKVS--------------------------------------
------------
>tr|R5YBC5|R5YBC5_9BACE DNA gyrase subunit A OS=Bacteroides sp. CAG:144 GN=gyrA PE=3 SV=1
-------HNYMLFFTQKGKCFWLKVYEIPEGAKNSKGRAIQNLLNADKVNAFIRVKLTHNLVFCTKKGVIKKTRLEAYSR-RT--NGV---NAITIREDD
QVIQVRLT---TGNSEIIMANREGRAIRFH---VREMRATGVRGMTLDSV-DVVGMICVNDTETIMVVSEQGYGKRSEI-DYRITNRGGKGVKTLNITTG
K-LVAIKNVT-ENDLVIINKSGITLRIKVADIRVMGRATQGVRLINLEKRN-DEIASVCKVA--------------------------------------
------------
>tr|R6BNA0|R6BNA0_9FIRM DNA gyrase subunit A OS=Firmicutes bacterium CAG:56 GN=gyrA PE=3 SV=1
-------HHYLMFFTNTGKVYRLKGYEIPEASRTARGTAIVNLLQPEKITAMIPVKQGKYLFMATRKGIVKKTPLLDYAN-RK--TGL---AAISLREDD
ELIEVK-T---NN-KDIFLVTKYGQCIRFPE--VRSMRAMGVIGMQLN---GVIGMQLNTQGDHLLIVSANGMGKLTSIDEFKSQNRGGKGVKCYKIMTG
N-VIGVKNLHD-DEIMMINTEGIVIRMMCSDISVLGRVTSGVKLMNLSE-N-VSVASIAKVR--------------------------------------
------------
>tr|R6PLZ4|R6PLZ4_9FIRM DNA gyrase subunit A OS=Eubacterium sp. CAG:274 GN=gyrA PE=3 SV=1
-------HSYLLYFTDMGRVYRTKTYNIPEG-RTAKGTPVVNIIEPEKISEIIPVK-NEYLVMVTKNGVIKKTPASEYESIRK--SGK---IAITLKEGD
ELISIFKT---TGNDNIFLATRNGMAICFN---ARAVRASGVKAIDLA---YVVGAEPVREDSKVLLVTDGGYGKCTDLTSFR-QHRGGKGLKAYKITTG
N-IIGISMVN-SEELIMVTSEGVVIRIRIKDIATTGRITQGVRLINLND-G-VIVVSMDKIS--------------------------------------
------------
>tr|A0A081BHI5|A0A081BHI5_9LACO DNA gyrase subunit A OS=Lactobacillus oryzae GN=gyrA PE=3 SV=1
-------HDVILFFTNAGKVYRMKGYEIPEYGRSAKGIPVINLLGNERVQAVINISSERFLFFTTVQGTVKRTPVDEFTN-RS--NGL---KAITLHEDD
ELMNVA-I---ED-DNMIIGTHQGYAVSFRS--VRSMRAAGVRGIRLR---DVIGADILEPNSKVFVISEKGFGKQTAASEYPIKGRGGKGIKTANITNG
P-LAGLATVSD-EDIMLVTDKGVMIRFGIEKVSETRRATLGVHLIRIDED--AKVATMTAVE--------------------------------------
------------
>tr|A0A0R1ZYH6|A0A0R1ZYH6_9LACO DNA gyrase, A subunit OS=Lactobacillus malefermentans DSM 5705 = KCTC 3548 GN=FD44_GL000981 PE=4 SV=1
-------HDVLLFFTNAGKVYRMKGYEIPEYGRSAKGIPVINLLGNEQVQAVINISEQRYLFFTTVHGTVKRTPVDEFTN-RS--NGL---KAITLKEND
ELMNIA-I---TD-DNMIIGTHLGYAVSFKS--VRSMRAAGVRGIRLR---DVIGADILQPDSKVFVISEKGFGKQTPANAYPIKGRGGKGIKTVNVSNG
P-LTGLATVSD-EDIMLVTNKGVMIRFGVEKVSETGRATLGVHLIRIDED--TKVATMAVVE--------------------------------------
------------
>tr|C0WMC6|C0WMC6_LACBU DNA gyrase subunit A OS=Lactobacillus buchneri ATCC 11577 GN=gyrA PE=3 SV=1
-------HDVLLFFTDAGKVYRMKGYEIPEYGRSAKGIPIVNLLNNEKIEAVINVSVQKDLLFVTLYGTVKRTPVSDFAN-RS--NGL---IAIHLKEGD
QLINAL-I---DQ-QNVIIGTHLGYAMSFNA--VRSMRATGVRGIRLR---NVVGADVLNPDSEVFIISEKGFGKRTPAADYPIKGRGGKGVKTANITNG
P-LSGLTTVSN-EDIMLITDKGVMIRFGIEDVSQTGRSTLGVHLIRIDED--SKVSTMAKVE--------------------------------------
------------
>tr|Q1NV33|Q1NV33_9DELT DNA gyrase subunit A OS=delta proteobacterium MLMS-1 GN=gyrA PE=3 SV=1
-------HDTLLFFSNKGRVFWRKVYEIPQAGRLARGKAVVNLLEAEKVAAILPVDGARYILMATKKGVVKKTALSEFAR-LK--RGK---IALTIREDD
EILGAS-T---TG-NEVLLLSRRGMAVRFHE--IRAMRASGVRGITLA-DDELIGLQVLSGEASILVVSENGFGKRSKVDEYRLIRRGGKGVMAIKASNG
E-VVGMSQVCD-DQVMMITNRGQIIRMPMQGIRVIGRSTQGVRLFNLDN-E-EKVVALDRLA--------------------------------------
------------
>tr|K1XZU8|K1XZU8_9BACT DNA gyrase subunit A OS=uncultured bacterium (gcode 4) GN=gyrA PE=3 SV=1
-------HDTMLIFTSTGMLHWLRVFHIPEASRVAKGVSIANLL-NEKIASMITVREDKTIVMATKKGVIKKSNLSLFSNIRK--KGI---IAINIKEED
ALIQAA-S---SGKDDILLSTSKGLSIRFNE--VSEMRATGVRGVKLK---DVISMEIVKSILNLLIVCENGFGKRSPFEEFRITNRGGKGVISI--TNG
D-VVTALAVKDDDDIMVITSSGMMVRINVKGISIQGRNTQGVKIVNLKP-N-DKIVSITTIE--------------------------------------
------------
>tr|V4J458|V4J458_9DELT DNA gyrase subunit A OS=uncultured Desulfofustis sp. PB-SRB1 GN=gyrA PE=3 SV=1
-------LDTFLFFTNFGKVFWRKVYQLPMAGRTARGKAIINLLEEERVAAILPISASQTILTVTKYGKVKKTALREFAR-LK--KGK---RALTINEGD
EILSAH-L---GG-DTVFLISHHGLSIRFHE--VRTMRAAGVRGIKLK--DYVVAANVLASEESILIVTENGYGKRTIATEYRTQFRGGKGIIAIKPSNG
P-VIGAQIVDL-SDVILIADSGQMIRMGVESVRIIGRTTQGVRMINLSE-S-ERVVGMAVVD--------------------------------------
------------
>tr|E8RH59|E8RH59_DESPD DNA gyrase subunit A OS=Desulfobulbus propionicus (strain ATCC 33891 / DSM 2032 / 1pr3) GN=gyrA PE=3 SV=1
-------LDTFLFFTNKGRVFWRKVYELPLAGRTARGKAIVNLLEEEKVAAILPVADTVSVLTVTKQGRVKKTFISEYKR-LR--KGK---FGLTIRDDD
EILSAA-T---SG-DEIFLVTKKGLSIHFHE--VRAMRAAGVKGITLG--DEVVGVAVLK-DASILTVTENGYGKRTAVSEYKLQSRGGKGVFTIKTSNG
N-VVGVLPVVE-DQVMLVANSGKVIRMPMDTVRIIGRNTQGVRLINLDE-G-ELVVDMSMLA--------------------------------------
------------
>tr|M1P7I8|M1P7I8_DESSD DNA gyrase subunit A OS=Desulfocapsa sulfexigens (strain DSM 10523 / SB164P1) GN=gyrA PE=3 SV=1
-------HDTFLFFTNHGKIFWRKVYQLPLAGRTARGKAIVNLLNEEKVAAILPVAITKTILMVTRLGRVKKTSLEEFIK-LK--RGK---KALTINEDD
EIISAH-L---TG-DTIFLFSKYGSSIHFHE--VRTMRAAGVRGIRLK--DYVVGSIVID-DSSILTVTENGYGKRSPVADYRIQKRGGLGIMAIKTSNG
Y-VVGAMQVDD-SEVMLIADSGKMIRMPMSNVRVIGRTTQGVGLINLAD-D-ERVVAMDLVA--------------------------------------
------------
>tr|D6Z5P0|D6Z5P0_DESAT DNA gyrase subunit A OS=Desulfurivibrio alkaliphilus (strain DSM 19089 / UNIQEM U267 / AHT2) GN=gyrA PE=3 SV=1
-------HDTLLFFTNRGRVFWRKVYEIPQAGRLARGKAVVNLLDPEKLAAILPVQRECYILMATRKGVVKKTTIQEFSR-VR--RGK---IALTFREDD
EILAAA-T---YG-NEILLLSRKGMAVRFHE--IRPMRATGVRGINLG--DELVGVSVLSGETSILVVTENGYGKRTLVDEYRLIRRGGKGVMAIKASNG
A-VVGMLQVTE-DQVMMITNAGQIIRMPMTDLRVIGRNTQGVRLFNLGA-E-EKVVALDRLA--------------------------------------
------------
>tr|Q6AQJ4|Q6AQJ4_DESPS DNA gyrase subunit A OS=Desulfotalea psychrophila (strain LSv54 / DSM 12343) GN=gyrA PE=3 SV=1
-------LDTFLFFTNYGKVFWRKVYQLPLVGRTARGKAIVNLLEEEKLAAILPVTKSKTILMVTKQGRIKKTSLQEFRR-LR--KGK---RALTINEGD
EIIGAY-L---NG-DTVLLCTSKGKAIHFHE--VRTMRAAGVRGITLG--DEVVSAIVAS-NDSILVVTENGYGKRSPIEEYRIQKRGGKGIIGIKQSNG
D-LISAKQVSE-EEIMIIADSGKMIRMNLENVRIIGRSTQGVRLINLEG-D-EKVVSMDTVA--------------------------------------
------------
>tr|A0A0F2NDN9|A0A0F2NDN9_9DELT DNA gyrase subunit A OS=Desulfobulbaceae bacterium BRH_c16a GN=gyrA PE=3 SV=1
-------LDTFLFFTNHGKVFWRKVYQLPLAGRTARGKAIVNLLNEEKIAAILPITNNKTILMVTKFGRIKKTSLQEFIR-LR--KGK---RALTINEGD
EIIAAH-L---NG-DTVLLVTKQGMCIHFEE--LRTMRAAGVRGITLR--DVVVSAIVIE-DNSILIITENGYGKRSPIDEYRLQKRGGKGVIGIKRSNG
N-VIAAKQVDE-EEVILIADSGKMIRMDLSSIRVIGRSTQGVTLINLDE-N-EKVVGMDSVA--------------------------------------
------------
>tr|H1Z878|H1Z878_MYROD DNA gyrase subunit A OS=Myroides odoratus DSM 2801 GN=gyrA PE=3 SV=1
-------HQYMLFFTQKGKCFWMRVYEIPEGTKVSKGRAIQNLINNDKVKAFICTQNNHYVIMATKQGQVKKTPLEQYSR-RQ--NGI---NAITIKEDD
ELLEAKLT---DGKSKVLIAVKSGKLVRFD---TRPMRASGVRGITLAD--DVIGMVSVSDNSEILVVSENGYGKRSAL-EYRETNRGGKGVKTMNISTG
L-LVSINVVT-ADDLMIINKSGLTIRMRISDLRVMGRATQGVRLINIKG-N-DSIAAVCKVM--------------------------------------
------------
>tr|V6S0Y2|V6S0Y2_9FLAO DNA gyrase subunit A OS=Flavobacterium enshiense DK69 GN=gyrA PE=3 SV=1
-------HQYMLFFTQKGKCFWMRVYEIPEGSKTSKGRAIQNLINNDKVKAFICTQNNHYVIMVTKQGQVKKTSLEQYSR-RV--NGV---AAITIKEDD
ELLEAKLT---TGNSQVLIAVKSGKLVRFE---TRPMRASGVRGITLAEK-DVIGMVSIDRDSQILVVTENGYGKRTKVVVYRITNRGGKGVKTLNITTG
A-LISINNVT-EDDLMIINKSGLTIRMKVSDLRVMGRATQGVRLINIKG-K-DAIAAVCKVM--------------------------------------
------------
>tr|A0A0P9CU24|A0A0P9CU24_9GAMM DNA gyrase subunit A OS=Thiohalorhabdus denitrificans GN=AN478_08515 PE=4 SV=1
-------HQYILCFSNAGKVYWLKVYELPEAGRTARGKAIVNLLP-ERITTVLPVDEGRYVVMATSKGVVKRVDLMDFSRPRK--AGI---IAIKLDQGE
SLVGARIT---GGNDEMLMATNRGKAIRFPEQEVRIMRAHGVRGIEMAE--DLIGLQVVRPGWEVLTVTENGFGKRTPLDEYRLQGRGGQGILTIKVSNG
E-VVSVRLVHPDNEVMLVTSQGTLIRTPLEGISRMGRNTQGVRLIDLA-KG-ERVVGAERVE--------------------------------------
------------
>tr|B6VZH5|B6VZH5_9BACE DNA gyrase subunit A OS=Bacteroides dorei DSM 17855 GN=gyrA PE=3 SV=1
-------HNTMMFFTQKGKCYWLKVYEIPEGTKNAKGRAIQNLLNSDVVTAYLRVKNSHYVLFCTKNGVIKKTLLEQYSR-RQ--NGV---NAITIREDD
KVIEVRMT---NGDNEIIIANRNGRAIRFH---VRVMRATGVRGMTLDDG-DVIGMICIKDAESIMVVSEQGYGKRSDI-DYRKTNRGGKGVKTLNITTG
K-LVAIKSVT-GNDLMIINKSGITIRLKVAEVRIMGRATQGVRLINLEKRN-DQIGSVCKVT--------------------------------------
------------
>tr|F3QR05|F3QR05_9BACT DNA gyrase subunit A OS=Paraprevotella xylaniphila YIT 11841 GN=gyrA PE=3 SV=1
-------HNTMLFFTQKGRCFWMKVYEIPEGAKNSKGRAIQNMLNPDAINVCLRIKRSHYVVFCTKNGIIKKTCLQEYSR-RA--NGV---NAITIREDD
RVIGVRLT---NGENEIIIANRNGRAIRFH---VRAMRATGVRGMTIDDG-DVVGMVCVNDTETIMVVSEQGYGKRSDI-DYRVTNRGAKGVKTLNITTG
K-LVAIKVVT-ENDLMIINKSGITIRLKVADVRIMGRATQGVRLINLEKRN-DQISSVCKVQ--------------------------------------
------------
>tr|E1RIX3|E1RIX3_METP4 DNA gyrase subunit A OS=Methanolacinia petrolearia (strain DSM 11571 / OCM 486 / SEBR 4847) GN=gyrA PE=3 SV=1
-------HDYLLCFTSSGRVYWLKVYDIPEATRQSRGKAIVNLLEDEKVTAVIPVSEDEFFLFATLNGMVVKIPQVEFSRPRQ--SGI---YAITLKDGD
ELVHVM-A---VDSGEIILTTRMGQSLRFGI--ISLRRALGVKGIKLR---DLQDVTPVEK--HLLTITEKGYGKRTEFDEFRGHGRATMGVRNI--DSG
G-IVSSKAVSDDEDIILMSRSGIVIRTKVSEISIQKRGTRGVRIMKLDE-G-DSVVGFTILD--------------------------------------
------------
>tr|A0A0C3RI66|A0A0C3RI66_9PORP DNA gyrase subunit A OS=Sanguibacteroides justesenii GN=gyrA PE=3 SV=1
-------HNTMLFFTEKGKCFWLKVWEIPEGTKQSKGRAIQNLLNPDKVKAYINILNSNYIVLCSKQGIVKKTTLEAYSR-RA--NGV---NAITIKEGD
QLLDAKLT---NGENDIMIAVKSGKAIRFP---VRPMRASGVRGITLGE--DVIGMICVEP-ADILVVSENGYGKRSDIEDYRITNRGGKGVKTINLTTG
N-LISLIDVT-DDNLMIINRSGLTIRLDISTLRVMGRNTQGVKLINLRN-D-DAIAAVAKVS--------------------------------------
------------
>tr|F0R0H1|F0R0H1_BACSH DNA gyrase subunit A OS=Bacteroides salanitronis (strain DSM 18170 / JCM 13567 / BL78) GN=gyrA PE=3 SV=1
-------HNTLLFFTQKGKCYWLKVYEIPEGNRTSKGRAIQNLLNADKVTAYLRVKNSHYVLFCTKNGVIKKTVLEQYSR-RQ--NGV---NAITIREDD
RVIEVRMT---KGDNDIVIANRNGRAIRFN---VREMRATGVRGITLDDG-DVVGMICIKDKETIMVISEHGYGKRSDI-DYRKTNRGGKGVKTLNITTG
K-LVAIKSVT-ENDLMIINKSGITIRLKVADVRIMGRATQGVRLIDLGKRN-DSIGSVCKVN--------------------------------------
------------
>tr|I4CB96|I4CB96_DESTA DNA gyrase subunit A OS=Desulfomonile tiedjei (strain ATCC 49306 / DSM 6799 / DCB-1) GN=gyrA PE=3 SV=1
-------HDVLLCFSNRGRVHWLRVFQLPEESPYARGKAIINLL-PEKIRKILPVQTEGFVVMTSRQGKIKKTAIEEFSRPRL--SGL---IALTIDPDD
ELIDVN-T---TGENHILLATARGLAMRFHE--VRPMRARGVTGIRLK---DVIGMEVVSD-GTLLTITRSGFGKRTSLEEYPSKNRGGQGVITI--TLG
E-VVAVKVVGDTDHLLILTSGGKIIRLRMEEISVIGRNTMGRTLVRMDQ-G-EYVVDVARAE--------------------------------------
------------
>tr|F9DV54|F9DV54_9BACL DNA gyrase subunit A OS=Sporosarcina newyorkensis 2681 GN=gyrA PE=3 SV=1
-------HDTILLFTSRGRVFRKKGYEIPEYSRTAKGLPIINLIDKEKVTAMIPISEDHYLFFATKHGVIKRTSIMGYAN-RA--NGL---IALGLREED
ELISVK-T---DG-SDIAICTKQGMLIRFAE--IRPLRAAGVRGIRLR--DDVIGMDMVDEGDDILVVTEKGYGKRTPESEYRSQSRGGYGLKTMHMTNG
E-IVAMKAVNE-EDLMLITIHGILIRMSISDISIFGRSTQGVRLIRLAD-D-ERVATVAKVE--------------------------------------
------------
>tr|S2XGG8|S2XGG8_9BACL DNA gyrase subunit A OS=Paenisporosarcina sp. HGH0030 GN=gyrA PE=3 SV=1
-------HDTILFFTNTGKVYRAKGYEIPEYGRTAKGLPIVNLLGKEKVTAMIQMADDAYFIFTTRLGVTKRTPVSGFAN-RA--NGL---ISISLRDDD
ELISVR-T---DG-KHIIIGTRNGMLVRFEE--IRSMRASGVRGIRLR--DDVVGMEILEPGQEVLVVTENGYGKRTPEEEYRLQSRGGVGIKTSQITTG
P-LSAVKAVDS-EDLMLITINGMLIRMDVNSISITGRSTQGVRLIRLGD-D-ELVATVAKVE--------------------------------------
------------
>tr|E7RC39|E7RC39_9BACL DNA gyrase subunit A OS=Planococcus donghaensis MPA1U2 GN=gyrA PE=3 SV=1
-------HDTILFFTNKGKVYRKKGYQIPEYGRTAKGLPLVNLLEKEKVTAVIRVKEDSFFFFTTREGLSKRTPVTNYAN-RQ--NGL---IAISLREED
ELISVK-T---DG-KEMVIGTKDGALIRFPE--IRSMRASGVRGIRLR--GDVVGMEILDPNDNVLVITEKGYGKQTKESEYRVQSRGGMGIKTCQITNG
P-LVAVRTVNT-EDIMLITVNGILIRMDVNDISTTGRSTQGVRLIRLGD-D-EVVATVAKVK--------------------------------------
------------
>tr|B0MSS0|B0MSS0_9BACT DNA gyrase subunit A OS=Alistipes putredinis DSM 17216 GN=gyrA PE=3 SV=1
-------HNTMLFFTEKGRCYWLKVYEIPEGTRSSKGRAIQNVIQPDKVRAYINVKNNNYIIMCTKDGTIKKTKLEAYSR-RQ--NGV---NAIVIREGD
QLIEAKLT---SGSAEVMIAAREGKAIRFN---VRPIRGAGVRGISLD---DVVGMICIEPSQDVLVLSENGYGKRTDLD-YRITNRGGKGVKTINITTG
K-LISIQAVT-ENDLMIINRSGLTIRTAVDQIRVAGRATQGVRIINLRE-G-DAIASVIAVP--------------------------------------
------------
>tr|A0A060RBP8|A0A060RBP8_9BACT DNA gyrase subunit A OS=Mucinivorans hirudinis GN=gyrA PE=3 SV=1
-------HNTMLLFTEKGRCFWLKVYEIPEGSKTSKGRALQNVIAPDKVRAYINVRNNNYIIMCTREGIIKKTSLEAYSR-RT--NGV---NAITIKEGD
QLLEARLT---SGKAQVILAAKDGKSIRFE---VRAIRAAGVRGMNLEE--DLIGMLTVEPKSEILVVSENGYGKRTDIDDYRIQSRSGKGIKTIQITTG
K-LIAIQSVD-TKDLMIITRSGLTIRMPISEIRLTGRAAQGVKVINLRG-D-DSIASVVAVP--------------------------------------
------------
>tr|U5Q8E8|U5Q8E8_9BACT DNA gyrase subunit A OS=Bacteroidales bacterium CF GN=gyrA PE=3 SV=1
-------HSTMLFFTQKGKCYWLKVYDLPEGSKASKGRAIQNVLNPDKACAFINVNNNNYIVLCTKRGIVKKTSLEAYSR-RT--NGV---NAITIRDND
ELLEATLT---NGKNEILLAAREGKCVRFN---VRAIRGAGVRGINIT---DVIGMICVDPASHVLVVSENGYGKRSLLD-YRVVNRGGKGVKTLNITTG
K-LIAIKNVT-ENDLMIINKSGLTIRLDVASVRVAGRATQGVRLINIKD-G-DSIAAVCRVN--------------------------------------
------------
>tr|R5W6K5|R5W6K5_9BACT DNA gyrase subunit A OS=Alistipes sp. CAG:157 GN=gyrA PE=3 SV=1
-------HDTMLFFTEKGRCYWLKVYNIPEGTRTSKGRAIQNVIQPDKIRAYINVRENNYIVMCTREGIIKKTKLEAYSR-RQ--NGV---NAITVKEGD
QLIDANLT---SGRADIIIAAREGKAIRFP---VRPIRGAGVRAITIEG--DVVGMICMEPANDILVLSENGYGKRTDLDAYRTTNRGGKGVKTMQVTTG
K-VVSIQSVS-EYDLMIITRNGTAIRTAASDIRLAGRATQGVKVINLRA-G-DSIASVMAVP--------------------------------------
------------
>tr|G5H6D0|G5H6D0_9BACT DNA gyrase subunit A OS=Alistipes indistinctus YIT 12060 GN=gyrA PE=3 SV=1
-------HNTMLFFTEKGRCYWLKVYAIPEGSRSSKGRALQNVIQPDKIRAYINVRDNNYIIMCTKAGIVKKTRLEAYSR-RQ--NGV---NAITIKDGD
ELIEAKLT---TGNSEVLIAAKDGKAIRFN---VRPIRGAGVKGITIED--DVIGMVCVEPKEDILVVSENGYGKRTDLDDYRITNRGGKGVKTLQITTG
K-LIAIKSVT-ANDLMIINRSGLTIRIPVGDIRLSGRATQGVKVINLRD-G-DSIASVIPVP--------------------------------------
------------
>tr|L1NDG2|L1NDG2_9PORP DNA gyrase subunit A OS=Porphyromonas catoniae F0037 GN=gyrA PE=3 SV=1
-------HSTMLLFTQMGRCYWLKVYEIPEGTKGSKGRALQNLLNTDRVNAFICVKNSHYLLFCTKRGTIKKTLLEAYSR-RT--NGV---IAIDLRDDD
RLVGVSLT---DGNSEILIANRHGRAVRFN---VRATRAMGVRGMTLDGG-DVIGMISVA-EESILVVSEHGYGKRSLVEDYRITNRGTKGVKTLNVTTG
E-LVAFEAVT-EHDLMIINRSGITIRIHARDISVQGRATQGVRIIDLKKRG-DEIASVCRVL--------------------------------------
------------
>tr|C2MB60|C2MB60_9PORP DNA gyrase subunit A OS=Porphyromonas uenonis 60-3 GN=gyrA PE=3 SV=1
-------HATMMLFTATGRVYWLRVFEIPEGSKSSKGRHIQNLLDENRITAFLRIKNTHYLVFATEQGLIKKTLLAHYAN-RK--TGV---RAINLRDDD
QVVSVALS---NGNCEIFLANRNGRCVRFN---VRPMRATGVRGIRLDDP-DVVGMVVHRLDETILVISEKGYGKRSRIDDYRITKRGAKGVKTINVTTG
Q-LIDIRAVE-DDNIMIINKSGVAIRLSMEQVRVMGRATQGVKMIDLNKRS-DEIASICNVV--------------------------------------
------------
>tr|U2K613|U2K613_9PORP DNA gyrase subunit A OS=Porphyromonas sp. oral taxon 278 str. W7784 GN=gyrA PE=3 SV=1
-------HETMLLFTQMGRCYWLKVYEIPEGAKNAKGRALQNLLNPDRVNAFIRVKNSHYLIFCTKRGTIKKTLLEAYSR-RA--NGV---IAINLVEGD
QLVGVGLT---NGDSEILIANRNGRAVRFH---VRAMRATGVRGMTLDDG-DVIGMLTVA-EETILVISEQGYGKRSVVEDYRKTNRGTKGVKTLNITTG
E-LVAIRPVT-EHDLMIINKSGITIRVHARDISVQGRATQGVRIIDLKKRG-DEIASVCQVL--------------------------------------
------------
>tr|A0A0R2CST7|A0A0R2CST7_9LACO DNA gyrase subunit A OS=Lactobacillus senioris DSM 24302 = JCM 17472 GN=FC56_GL001273 PE=4 SV=1
-------HDILLFFTDAGKVYRMKGYEIPEYGRAAKGIPIINLLNDEKIQAVINVAVDKDLFFTTLLGTVKKTPVAEFTN-RS--NGL---KAIHLKDGD
QVTNVL-A---DD-ENIIIGTHQGYAVSFRA--VRTMRATGVRGIRLR---DVVGSDILAPDSDVFVISEKGYGKKTPASEYPIKGRGGKGIKTVNVTNG
P-LAGLTTVKD-EDIMLITDKGVMIRFGIEKVSQTGRATLGVHLIKMDGE--SKVATMAKVE--------------------------------------
------------
>tr|A0A0A6RGV4|A0A0A6RGV4_9LACO DNA gyrase subunit A OS=Lactobacillus curieae GN=gyrA PE=3 SV=1
-------HDVLLFFTDAGKIYRMKGYEIPEYGRSAKGIPIINLLSEEKIQAVINISTEKDLFFVTTQGTVKRTPVAEFTN-RS--NGL---KAIHLKDGD
EVNNVL-V---EE-QNIIIGTHRGYAVSFKA--VRSMRATGVRGIRLR---EVVGSDILDPESEVFIISEKGYGKRTPAAQYPIKGRGGKGIKTANITNG
P-LAGLTTVSQ-EDIMLITNKGVMIRFDVNGVSETGRATLGVHLIRMDDD--AKVATMAKVE--------------------------------------
------------
>tr|A0A0R1SK41|A0A0R1SK41_9LACO DNA gyrase subunit A OS=Lactobacillus diolivorans DSM 14421 GN=FC85_GL000401 PE=4 SV=1
-------HDVLLFFTDAGKVYRMKGYEIPEYGRSAKGIPIVNLLNNEKIEAVINISIEKDLFFVTLLGTVKRTSVSEFAN-RS--NGL---KAIHLKDDD
QVMNVL-V---DQ-QNIIIGTHRGYAVSFKA--VRSMRATGVRGVRLR---NVVGSDTLNPDSEVFIISENGYGKRTSAGEYPIKGRGGKGIKTANITNG
P-LAGLTTVSK-EDIMLITNKGVMIRFAIEDVSQTGRATLGVHLIRMDDD--AKVATMAKVE--------------------------------------
------------
>tr|J9W4D9|J9W4D9_LACBU DNA gyrase subunit A OS=Lactobacillus buchneri CD034 GN=gyrA PE=3 SV=1
-------HDVLLFFTDAGKVYRMKGYEIPEYGRSAKGIPVINLLNGEKIQAVINVSIEKDLFFVTLMGTVKRTPVSDFAN-RS--NGL---KAINLKDDD
QVSNVL-A---SE-QNIIIGTHRGYAVSFNA--VRSMRATGVRGVRLR---NVVGSDILKPDSEVFIISENGYGKRTPAAEYPIKGRGGKGIKTANITNG
P-LAGLTTVNE-EDIMLITDQGVMIRFSVEDVSQTGRATLGVHLIRMTDG--AKVATMAKVE--------------------------------------
------------
>tr|R6BDC4|R6BDC4_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:169 GN=gyrA PE=3 SV=1
-------HDYLMFFTNKGKVYRIKGYEIPES-RTSRGTNVVNILPQEKITCVIKTSEDRYYVMVTRNGVIKRTEYNAYTNVRK--SGL---IAINLDEGD
ELAWVKIT---DGHSDVVLATRQGMSIRFH---ARSMRARGVKAISLE---QVVGMVVLSAAGDILTVSQSGLGRRTDSEEYRLQTRGGKGLRNYYCDNG
P-VAGFEMVD-T-DIILITDSGIIIRIPADQISK-SRYAGGVKVMRVDD-Q-TSIIGIAVTE--------------------------------------
------------
>tr|B0PBP1|B0PBP1_9FIRM DNA gyrase subunit A OS=Anaerotruncus colihominis DSM 17241 GN=gyrA PE=3 SV=1
-------HDFIMFFTSKGRCFRLKGYEISES-RTSRGTNIVNLLSSEKVTALIKVTEDRCLVMVTRKGIIKRTPLGAYKNVRR--MGL---IAIGLDDGD
ELAWVRQT---DGTSELIIATKNGMAIRFD---ARPLRARGVKAITLE---EVVGMARVRKGATLLTVSESGLGRRTEVSQYRLQSRGGKGIRNYYVDNG
P-VAGVRMVD-D-DVIIITDDGVIIRIPVREITV-SRYGGGVRAMRVSE-E-SRVVTLARAP--------------------------------------
------------
>tr|R6U1N6|R6U1N6_9BACE DNA gyrase subunit A OS=Bacteroides sp. CAG:770 GN=gyrA PE=3 SV=1
-------HSTMLFFTEQGKCFWLKVYEVPEGSRSTKGRAIQNVLSDDKIKAIINVPNNHYIILSTKEGIIKKTSLEAYSRPRA--KGV---NAVNVREGD
ELLEAILT---DGRSEVLIASRNGRCVRFDE--ARPLRATGVRGINLD---SAIGMVCYEPEHTLLVIGEKGLGKRTDFEEYRKTSRGSKGVRTM--TTG
K-LVAMKNVTEDNDLLIITQSGLIIRMAVSDIAQSGRNTQGVKLINIRD-N-DSIASVSVVA--------------------------------------
------------
>tr|R6X9B5|R6X9B5_9BACT DNA gyrase subunit A OS=Alistipes sp. CAG:435 GN=gyrA PE=3 SV=1
-------HSTMLLFTQAGRCYWLKVYEIPEGSRASKGRAIQNVLSPDKILAYINVKNGNNIVLITKRGIIKKTSLEAYSH-RT--AGV---NAVNLREGD
ELVEALLT---NGNEEIFIAAREGRCCRFD---ARPMRSTGVRGINIE---DVIGAINYDPAHTVLVVSENGFGKRTDFDEYRITKRGGKGVKTISITTG
K-LIAIKNVT-NNDLMIIEKSGLTIRMAVSDIRVAGRATQGVKLINIKN-G-DSIAAISTVE--------------------------------------
------------
>tr|R5BLW3|R5BLW3_9BACE DNA gyrase subunit A OS=Bacteroides sp. CAG:1060 GN=gyrA PE=3 SV=1
-------HSTMLLFTDKGMCYRLKVYELPEGSRTSKGRAVQNLLSSDSIRTYLNVRNSHFVTLVTKRGVVKKTTLSEYSN-RN--KGI---IAINIREGD
ELLDALLT---DGTENILIAAKAGRCCRFN---LRALRSSGVRGISIE---DVIGAIAHKMGHSILVVSENGFGKRSDYE-YRLTSRGAKGVKTINITTG
T-LVAIKDVT-ENDLMIITKSGLTIRMAVSEIRIAGRATQGVKLINIRE-G-DSIAAVCPVA--------------------------------------
------------
>tr|C2FB28|C2FB28_LACPA DNA gyrase subunit A OS=Lactobacillus paracasei subsp. paracasei ATCC 25302 GN=gyrA PE=3 SV=1
-------HDVLLFFTNKGKVYRSKGYEIPEYGRTAKGIPIINLLGGEKIQTVINVHDDRYLFFVTQKGVVKRTPVKEFAN-RS--NGL---IALNLKDED
ELNNVI-T---SG-DNILIGTHLGYSVTFKE--VRSMRATGVRGIRLR---HVVGSDILKPDSEVFVISEKGYGKRTAAKEYPIKGRGGKGIKTANITNG
P-LAGVTTVDT-EDILVMTDSGVMIRFNIQSVSQTGRATLGVRLIRVDDD--AKVATMAKVE--------------------------------------
------------
>tr|C8N900|C8N900_9GAMM DNA gyrase subunit A OS=Cardiobacterium hominis ATCC 15826 GN=gyrA PE=3 SV=1
-------HDTMLCFTNRGKVYWLKVYELPQAGRNAKGKPMVNLLP-ERLNAVLTTREDQYLIFATKSGTVKKTPLSEYSRPRS--IGI---IAINLREDD
ELVDVART---DGSRDIMLFSDAGKAVRFNENSVRSMRSTGVRGMNLDD--QVIALCVVEEQGDILTITENGYGKRTPVADYPQKGRGTKGVISIACSNG
Q-AVCAVQVLEDEHIMLVTDNGTLVRTRVAEISTSGRNTQGVRLIRTT-DS-EKLIAVAKIV--------------------------------------
------------
>tr|A5EW68|A5EW68_DICNV DNA gyrase subunit A OS=Dichelobacter nodosus (strain VCS1703A) GN=gyrA PE=3 SV=1
-------HDTMLCFSNKGKVYWLKVYELPHASRNAKGKPIVNLLP-ERLNAILTTREDLYLFFATQNGTVKKTPLSEYSRPRA--NGI---IAINLRDDD
QLVDVELT---NGERNIMLFSNAGKAVRFSEETVRSMRAGGVRGMRLEA--QVIALCVLKDQGDILTITENGYGKRTPTADYPQKGRGTKGVISIMCSNG
N-AVYAIQVCEDEDIMLVTDNGTLVRTRVCEISTSGRNTQGVRLIRTA-ES-EKVIAAAKII--------------------------------------
------------
>tr|I3DLC1|I3DLC1_HAEPH DNA gyrase subunit A OS=Haemophilus parahaemolyticus HK385 GN=gyrA PE=3 SV=1
-------HDTILCFSSRGRLYQLKVYQLPQASRGARGTPIVNILPEERITAILPIPADKFVFMATASGVVKKVALDAFSN-RA--NGL---IALTLRDGD
ELIGVDIT---NGESEIMLFSAQGRVVRFEEKAVRAMRATGVRGIKLAKINTVVSLVIPRAEGDILTVTQNGYGKRTVLVEYPVKSRATKGVVSI--NNG
K-VVAAVQVE-TDQIMLITDAGTLVRTRVSEVSLVGRNTQGVRIIRTAE-D-EQVVSLERIC--------------------------------------
------------
>tr|W0R6H5|W0R6H5_BIBTR DNA gyrase subunit A OS=Bibersteinia trehalosi USDA-ARS-USMARC-190 GN=gyrA PE=3 SV=1
-------HDVILCFSSRGRVYQLKVYQLPQASRAARGTPIINILP-ERITSILPIQEDKFVLMATASGIVKKVTLDAFSN-RS--NGL---IALNLRDGD
ELIGVDIT---DGESEIMLFSAQGRVVRFKESAVRAMRATGVRGMKLATLNKVVSLVIPKNEGEILTVTQNGYGKRTKLAEYPTKSRNTKGVVSI--NNG
K-VVAAVQVI-SDQIMLITDGGTLVRTRVGEVSLVGRNTQGVRIIRTIE-G-ESVVGLERIA--------------------------------------
------------
>tr|A0A0H4HZY0|A0A0H4HZY0_9ALTE DNA gyrase subunit A OS=Marinobacter psychrophilus GN=gyrA PE=3 SV=1
-------HDTILCFSNRGKVYWLRVFEIPRASRASRGRPMVNILP-ERITTFLPVREDQFVLMATSAGVVKKTPLPNFSRPRS--SGL---IALSLDEGD
TLIGAAIT---DGSAEIMLFSTAGKAVRFKEEAVRPMRARGVRGIRMA--EGVVSLIIPQDNAVLLMASEHGYGKRTNLDEFPTYGRGSQGVIAMQCSNG
N-LVTALQLFDGDEMMLISDKGTLVRTRTDEVSVLSRNTQGVRLIKLSQED-ERLVGVERIA--------------------------------------
------------
>tr|M7D750|M7D750_9ALTE DNA gyrase subunit A OS=Marinobacter santoriniensis NKSG1 GN=gyrA PE=3 SV=1
-------HDTILCFSNRGKVYWLRVFEIPRGSRGSRGRPMVNILP-ERITTFLPVREDQFVLMATSNGVVKKTPLPNFSRPRS--SGL---IALNLDDGD
TLVGAAIT---KGDAEVMLFSSAGKAVRFAEDQVRPMRARGVRGIRMP--EGVVSLIIPEEGGVILTASEHGYGKRTAIDEFPTYSRGSQGVIAMQCSNG
D-LVTALQLFDGDEMMLISDKGTLVRTRTDEVSVLSRNTQGVRLIRLAQED-ERLVGVERIA--------------------------------------
------------
>tr|N6VW28|N6VW28_9ALTE DNA gyrase subunit A OS=Marinobacter nanhaiticus D15-8W GN=gyrA PE=3 SV=1
-------HDTILCFTNKGKVYWLRVFEIPQASRAARGRPMVNILP-ERVTTFLPVREDHYVLMATSAGVVKKTPLPNFSRPRS--NGL---IALSLDEGD
TLIGAAIT---AGESEVMLFSSAGKAVRFKEEQVRAMRARGVRGIRMP--EGVVSLIIPEESGMILTASENGYGKRTQIEEFPAYSRGSQGVIAMQCSNG
N-LVSATQVFESDEMMLISDKGTLVRSSTEEVSVLSRNTQGVRLIRLTQED-ERLVAVQRIA--------------------------------------
------------
>tr|A0A0F9W2T1|A0A0F9W2T1_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_0021480 PE=3 SV=1
-------HDTLLCFSSAGKVYWLRVFNIPLASRTSRGRPLVNILP-ERITSMLPIREGYFIFMATAMGTVKKTSLTSFSRPRS--VGL---RAIELDEGD
RLVGTALT---DGQRDIMLFGSGGKVLRFNEAGVRTMRARGVRGIRLAAQE-MIALIIPE-GHQVLTVSENGYGKRTDVAEFPVYGRGGQGVIGMQTSNG
A-LVGAVQVADGGQIMLISNKGTLVRIRVDEVSVLSRNTQGVRLIKLK-KD-ELLVGVEPVA--------------------------------------
------------
>tr|A0A0F5JUU3|A0A0F5JUU3_9BURK DNA gyrase subunit A OS=Burkholderia andropogonis GN=gyrA PE=3 SV=1
-------HDYILCFSNRGRVYWVKVYEVPQGSRNSRGRPIVNMFP-EKINVVLPVR-DRYVFMATALGTVKKTPLEQFSRPLR--KGI---IAVSLDEGD
YLIGAAIT---DGKHDVMLFSDAGKAVRFDEGDVRAMRARGVRGMQLE--DGVIAMLVAENQQSVLTATANGFGKRTPIEEYTRHGRGTKGMIAIQTSNG
K-VVAATLVEPSSELMLITTSGVLIRTRVSEIREMGRATQGVTLISLD-EG-TYLSGLQKVV--------------------------------------
------------
>tr|A0A0Q7Y1G9|A0A0Q7Y1G9_9RHIZ DNA gyrase subunit A OS=Rhizobium sp. Root149 GN=ASD54_07285 PE=4 SV=1
-------HTPVLFFSSRGIVYKEKVWRLPIGTPQSRGKALINMLPPERITTIMPLPANLDVMFSTTRGTVRRNKLSDFIQVNR--NGK---IAMKLEEGD
EILSVE-S----PGDDVLLTTALGQCIRFPD--VRVARSIGVRGITLA---DLISMTIVGHEQFVLTISERGFGKRSSSYDFRTSGRGGKGIRATDT-IG
E-LVAAFPVE-KDQLMLVSNGGQLIRVPVDGIRIASRATKGVTIFSTAK-D-E-VVSVERIS--------------------------------------
------------
>tr|A0A0R2S4S6|A0A0R2S4S6_9FLAO DNA gyrase subunit A (Fragment) OS=Cryomorphaceae bacterium BACL11 MAG-121128-bin16 GN=ABR81_04790 PE=4 SV=1
-------HDYMLFFTEQGKCFWLKVYEIPEGSKTSKGRAIQNLINKDKVMAYINTKNSHYIVMCTKQGVIKKTSLEQYSR-RT--NGI---NAITIREGD
QLLEAKMT---TGKSQIMMAVKSGKSIRFE---VRAMRAAGVRGVRLAK--DVVGMICIDDQSSVLVVSEHGYGKRSDVEDYRITNRGGKGVKTINITTG
N-LIALKNVT-LDDLMVINKSGITIRIGVDTLRVMGRATQGVKIIRLRD-E-DSIASVAKVS--------------------------------------
------------
>tr|U3XR81|U3XR81_PEPDI DNA gyrase subunit A OS=Peptoclostridium difficile E15 GN=gyrA PE=3 SV=1
-------HSRLLFFTNKGRVFKLNAYEIPEGKRQAKGTAIVNLLQAEKIATLIPIDENEYLLLATKKGIVKKTKREEFKN-NK--SGL---IAIGLRDDD
ELIGVE-T---DG-QEVLLVTKEGMSIRFDE--IRYMRAMGVKGITLS---EVVSMNLCSKGTDVLVVSKNGFGKRTNIEEYRSQIRAGKGIKTYNISTG
T-IVGADMVND-DEIMIINSDGVLIRIRVNEISLFGRVTSGVKLMKTNDE--VNVVSIAKIN--------------------------------------
------------
>tr|D9PQV0|D9PQV0_FINMA DNA gyrase subunit A OS=Finegoldia magna ACS-171-V-Col3 GN=gyrA PE=3 SV=1
-------HQDLLFFTNKGKVYSLKAYEVPE-SRTARGSNIINLIQAENVTQVLALDNDQFIIFITKKGKVKKTSLSLYENIRK--TGI---IAIKFDEGD
ELIDVKLV---EKNEEVIIVTKKGMSLQFN---LRDLRAIGVKAITLN---EVISFDLVK-NEFLAVISENGYGKKTELSNYTTQNRGGKGIRTYKIATG
D-VACAKALK-EDEILLISKQAEVIRIKAEGIST-SRNTSGVLLKNTDKGE-DAIVAVAKYF--------------------------------------
------------
>tr|A0A0B3VVK8|A0A0B3VVK8_9FIRM DNA gyrase subunit A OS=Terrisporobacter othiniensis GN=gyrA PE=3 SV=1
-------HSRLLFFTNKGRVFRMDAFEIPEGKRKAKGTAIVNLLQPEKITTLIPVDEELYLLLATKKGIVKKTKREEFKN-NK--SGL---IAIGLRSDD
ELIDVK-T---NG-KDVLLVTENGMSIRFNE--IRPMRAMGVKGITLS---DVVSMNLTDEGHELLVVSEKGFGKRTDINEYRVQSRAGKGIKTYNIFTG
K-IVGAEMVDK-DQMMLINSDGILIRLQVEGISIYGRVTSGVKLMKTEDE--VNVVSIAKIN--------------------------------------
------------
>tr|I0GJ27|I0GJ27_CALEA DNA gyrase subunit A OS=Caldisericum exile (strain DSM 21853 / NBRC 104410 / AZM16c01) GN=gyrA PE=3 SV=1
-------KSTMLFFTNIGKVYSLRAFEIPELERTGKGTPIHRLLKPENISKVISIEKIKSLLFVTRKGLVKKTKMEEFVYITS--AGK---IALKLKDDD
ELETVIPI---LEESDVMMISNAGLAVRFDT--VREMRSSGVIGMKVK---FVVDAE--ILEDKVILVTEKGYGKILSVKEIRKTKRGAKGVKCI--STG
N-LVAVKVIHDEENLYLLLKSGNVIKIELKDVKELGRNTRGVILVRFKE-G-EDTVSAIALE--------------------------------------
------------
>tr|A0A0P1P512|A0A0P1P512_9BACT DNA gyrase subunit A OS=bacterium JGI-24 GN=JGI24_01700 PE=4 SV=1
-------HHYIIFFTDKGKAYWLKVHEIPEGSRTSRGKSISYLVNPEKITAFVAVR-NLFVTMVTKMGYVKKVPLMEFSN-RR--VGI---IAINLNRGD
RLVDAR-T---DG-QDLIIGTKKGIAIRFNE--IRPMRATGVRGIKLE--DEVIGMIAVKRGATILVVTENGFGKRSDLNDYRVTHRGGKGIIAVKVNTG
N-MVAIKEVLN-DDIMIVTAKGYLIRHHVKDIRVMGRQAQGVKLIKLNHG--DIIASVASVV--------------------------------------
------------
>tr|A0A0P1LLM4|A0A0P1LLM4_9BACT DNA gyrase subunit A OS=bacterium JGI-7 GN=JGI7_00440 PE=4 SV=1
-------HHYIIFFTDKGRAYWLKVHEIPEGSRASRGRSISHLINPEKITAFVTVK-NLFVTMVTKMGLVKKVALSEFSN-RK--IGI---IAINLNRGD
RLVDAR-T---DG-QDLIIGTRKGMAIRFNE--IRPMRATGVRGVKLE--DEVIGMVTVKRGTTILVVTEKGFGKRSDLNDYRVTHRGGKGIIAVKVNTG
D-MVAIKEVLN-DDIMVVTAKGYLIRYHVKDIRVMSRQAQGVKLIKLNHG--DTIASVASVV--------------------------------------
------------
>tr|Q3A8P8|Q3A8P8_CARHZ DNA gyrase subunit A OS=Carboxydothermus hydrogenoformans (strain ATCC BAA-161 / DSM 6008 / Z-2901) GN=gyrA PE=3 SV=1
-------HNYLLFFTNKGKVYRLKVHEIPEAGRQAKGTPIVNLLYQERITAIIPVK-DHYLFMVTKNGIVKKTVLSEYDS-RR--DGI---IALSLEEGD
KLIDVK-S---TG-EEVIIGTKKGMAIRFSE--VRPMRARGVKGITLS---GVIGLEVVDEQAELLTVTSKGFGKKTPFSEYRVQGRGGKGIINMKVTNG
E-VVGIVAVRE-DEVMAISGEGIMIRVKAAEISTQGRATQGVTLMKLNKD--DQLTAVAKIA--------------------------------------
------------
>tr|A0A0F2Q535|A0A0F2Q535_9CLOT DNA gyrase subunit A OS=Clostridiaceae bacterium BRH_c20a GN=gyrA PE=3 SV=1
-------HNYLMFFTNKGKVYRLKVYEIPEASRQSKGTAIINLLYGEQITTVIPVK-NWYLFAATQKGIVKKTDLSEYDT-RK--DGI---IAISLADDD
ELMGVQ-T---DG-QDVILVTKEGLSIRFNE--VRSMRAHGVRGIRLD---DVVGMDIIRNDSQLLVITDKGYGKRSPVEEYRTQSRGGKGIITLRITNG
K-LVGTKVVKG-EEIMIISKEGIIIRLKTDDISSMSRTTQGVLIMRVGEE--DAVVAIARVV--------------------------------------
------------
>tr|B2A2Z3|B2A2Z3_NATTJ DNA gyrase subunit A OS=Natranaerobius thermophilus (strain ATCC BAA-1301 / DSM 18059 / JW/NM-WN-LF) GN=gyrA PE=3 SV=1
-------HNYILFFTNKGKVYRLKVYEIPEASRQARGTAIVNLLAPEHITAVIPIQ-DDYLFFVTKQGVAKKVILSELKA-RK--DGL---IAINLNEDD
ELIDVH-T---DG-QEIILGTEQGLAIKFSE--VRSMRSRGVKGISLK---NVIGMDIAQENSDLLIVSENGYGKRTPVSEYRTQSRGGKGIYTFKPSSG
N-LAGCIVVND-EEIILVTAQGVINRQQVEGISQMSRRTQGVRLIKLKDD--DQVVSLAIPE--------------------------------------
------------
>tr|A0A085LA42|A0A085LA42_9FIRM DNA gyrase subunit A OS=Peptococcaceae bacterium SCADC1_2_3 GN=gyrA PE=3 SV=1
-------HHHVLFLTNKGKSYRLKVHEITEASRLARGTPIFNLLKPEKITTVIPVV-GKYIFMATRFGLVKKTPLESFKN-RR--DGI---IAVSLKPGD
SLIGAK-T---DG-QEIVLGTRRGLVIRFSE--VPAHRSRGVKGVTLK--DIVVSMDVAQP-ASLLAVTANGYGKCTTLKKYRLQSRGGKGLISIRNNNG
P-VVAFLVASD-EEIMLISAEGIVLRMKTTEINLTSRITRGVILMRLAAN--DKIVDVTRVE--------------------------------------
------------
>tr|F6CIH8|F6CIH8_DESK7 DNA gyrase subunit A OS=Desulfotomaculum kuznetsovii (strain DSM 6115 / VKM B-1805 / 17) GN=gyrA PE=3 SV=1
-------HHYFLFFSNRGKVYRLKVHEIPEAGRQAKGTALVNLIYPERITAVIPVR-GLYLFMATRFGVVKKTQLEQFDT-RR--DGI---IAIKLDDQD
ELVEVK-T---SG-EEIILGTRQGLAIRFPE--VHPYRARGVKGITLQ---GVVAMDIVRPDGDVLVVTANGYGKRTPVSDYRLQSRGGKGIISARVTNG
P-VVAMQVVKD-EEIMVISAEGIIIRLKASDISTMGRATQGVMLMRLAPG--DKLVAAALVS--------------------------------------
------------
>tr|C8VVA3|C8VVA3_DESAS DNA gyrase subunit A OS=Desulfotomaculum acetoxidans (strain ATCC 49208 / DSM 771 / VKM B-1644) GN=gyrA PE=3 SV=1
-------HHYILFFTNKGKVYRLKVHEIPEAGRQSKGTAIINLLFTEKVTTVIPVK-DEFLFMCTKNGIVKKTSLNEFDT-RR--DGI---IALTLDDHD
DLVDVR-T---NG-EEIIIGTQKGLAIRFSE--VRKLRAKGVRGIGLI---GVVGMDTVRNEGDLLVVTKNGFGKKTPISEYRLQTRGGKGIINVKISNG
P-VVSLLVVKD-EEIMMLSSEGIIIRMKVNEISTTGRATQGVTLMKLSSG--DSVATIAKVN--------------------------------------
------------
>tr|Q9RT53|Q9RT53_DEIRA DNA gyrase subunit A OS=Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279
-------HDYLLFFTDQGRVFHEKIYDLPEAGRDAKGTHIRNLLP-ENIASVLSVSQPGSFIFATKSGVIKKSLITDYANITS--AGL---IAINLQPGD
ELIGVD-Q---QDGDDVVLATKNGQAMRFEA--VRDTRTQGVIGIRLR---EVVSMALVPGEGELLAISECGLGKRTKVSDYPSKGRGGLGVITL--TTG
K-LVTLAHVAGNEELMVLTEKGTVIRTRVEEVRVTGRNAQGVKVINIGD-K-DRVIDAFPIR--------------------------------------
------------
>tr|A0A072NC30|A0A072NC30_9DEIO DNA gyrase subunit A OS=Deinococcus sp. RL GN=gyrA PE=3 SV=1
-------HDYMLFFTDQGRVFHEKIYDLPEAGRDAKGTHIRNLFP-ENIASVLSVKEPGSFVFATKRGMIKKTLITEYGNITS--AGL---IAINLQPGD
ELIGVG-Q---RNGDHVVLATRNGQAMRFAA--VRDTRTQGVIGIRLR---EVVSMALVPGGSELLAISECGLGKRTPVSEYPSKGRGGLGVITL--TTG
G-LVALTHVAGNEELMVLTEKGTVIRTRVEEVRVTGRNAQGVKVIHLGS-G-DRVIDAFPIR--------------------------------------
------------
>tr|H8GZC0|H8GZC0_DEIGI DNA gyrase subunit A OS=Deinococcus gobiensis (strain DSM 21396 / JCM 16679 / CGMCC 1.7299 / I-0) GN=gyrA PE=3 SV=1
-------HDYLLFFTDQGRVFHEKIYDLPEAGRDAKGTHIRNLLP-ESIASVLSVGAAGCFIFATKNGMVKKTLITDYSNITS--AGL---IAINLQPGD
ELIGVG-V---QDSDHVVLATQNGKAMRFEA--VRATRTQGVIGIRLR---DVVSMALIPVGVELLAVSEYGLGKRTPVSDYPAKGRGGMGVITL--TTG
Q-LVTLARVAGDEELMVLTEKGTVIRTRVEEVRVTGRNAQGVKVINIAD-K-DCVISAFPIR--------------------------------------
------------
>tr|A0A0A7KEZ4|A0A0A7KEZ4_9DEIO DNA gyrase subunit A OS=Deinococcus swuensis GN=gyrA PE=3 SV=1
-------HDFLLFFTDQGRVFHEKIYDLPEAGRDAKGTHIRNLLP-ENIASVLSVKEKGCFIFATRKGVVKKTLITDYGNITS--AGL---IAINLQNGD
ELIGVG-V---QDDDHVVLATRNGKAMRFQS--VRDTRTQGVIGIRLR---DVVSMALVPGTSELLSVSECGLGKRTPVGDYPAKGRGGMGVITL--TTG
K-LVTLARVAGDEELMVLTEKGTVIRTRVEEVRVTGRNAQGVKVINIGD-K-DSVISAFPIR--------------------------------------
------------
>tr|F2LWE3|F2LWE3_HIPMA DNA gyrase subunit A OS=Hippea maritima (strain ATCC 700847 / DSM 10411 / MH2) GN=gyrA PE=3 SV=1
-------LNTLLCFTNLGRVYSVKAYNIPKQSPSAKGRPIVNILNPEFVKTIVPIS-ADSLFFATAAGTVKRSSFRHFENIPS--NGK---IAIRLNEQD
SLVSVFSV---AEGDEVIITTRRGMCVRFDS--VRDMRAAGVRGINLS---SVVSAFNFNQ-TKLIVVSQTGLGKLLRVSDIRKVNRGAKGVRCI--KND
S-VAGSLSLKDTGDVIVVTKNGKMIKMDADSINVFSRAARGVKLINLDE-A-DSVVSIVVAG--------------------------------------
------------
>tr|W0JGQ7|W0JGQ7_DESAE DNA gyrase subunit A OS=Desulfurella acetivorans A63 GN=gyrA PE=3 SV=1
-------LDVVLMFSNNGRIYSIKAYEIPKSSNYTKGKAIVNLLNNEQIKTINAYK-GNDYVLITQKGIIKRISSDNFSDIKS--NGR---TIINLLNDD
QLVCVINV---SEKDEIIICTSLGQSVRFGI--VRKMRAYGVKGISLA---YVVSGFKLQN-EKIVLITQNGIAKVILADSIRKVSRGAKGVKII--KED
R-LVDAERLQDNSEILITTKLGKLIRIDSNQFREMSRYAYGVKAIELES-D-DSVVKVNVTK--------------------------------------
------------
>tr|B1I1I1|B1I1I1_DESAP DNA gyrase subunit A OS=Desulforudis audaxviator (strain MP104C) GN=gyrA PE=3 SV=1
-------HDYLLFFTERGKVYRVKVYEIPEAGRQARGTAVVNLIPNERVTAVIPVT-DAFLFMVTRKGIVKKTVLQEFDS-RR--DGL---IALTLDEGD
ELVDVK-T---DG-SEVLLGTRNGMVIRFPE--VRPMRAHGVRGISLR--DMVVGMDIVDP-DQLLVVSEKGYGKVTPVKEFRVQSRGGFGLIAARVSNG
P-LVSLSLVGG-EEILIVSKSGILIRMKIDEIPQFGRQAQGVRLMRLAPG--DAVVAVAWIL--------------------------------------
------------
>tr|C9RA74|C9RA74_AMMDK DNA gyrase subunit A OS=Ammonifex degensii (strain DSM 10501 / KC4) GN=gyrA PE=3 SV=1
-------HDYLLFFTSAGRVHRLKVYEIPEAERAGRGTALPNLLQPEQVTAIIPVA-DKYVLLVTRQGVVKKLPLGELAN-RR--VGL---NAISLDPGD
ELVAAA-P---GP-EEVLLVTEGGKAIRFRA--VRPMRARGVRGMKLR--DRVAGLAVLDG-GEVLLVTAGGYGKRVKTADFPLQGRGGMGVTALAVSSG
P-VVGVEVVRE-EEILLASAAGWLTRLKVKEVPVMGRQARGVVLMRLQPE--DRLVALAKIG--------------------------------------
------------
>tr|A0A0M2U7E3|A0A0M2U7E3_9FIRM DNA gyrase subunit A OS=Clostridiales bacterium PH28_bin88 GN=gyrA PE=3 SV=1
-------HHFLLFFTNRGKVYRLKVHEIPEAGRQAKGTAIVNLLYGEKITAVIPVR-EKYLFMATRHGTVKKTALGEFDS-RR--DGI---IAINLDEED
ELIGVH-T---EG-QDIILGTRFGVAIRFPE--VRATRTRGVKGITLS---EVVSMDSVRPGADLLAVTENGFGKRTPLEEYRPQGRGGRGIIAIRTSNG
S-LVAIMVVEG-DELMMVSSEGIIIRIDVADVSRMGRAAQGVTLMRLGEN--DRVVAVARVP--------------------------------------
------------
>tr|A0A0F2PLK8|A0A0F2PLK8_9FIRM DNA gyrase subunit A OS=Peptococcaceae bacterium BRH_c8a GN=gyrA PE=3 SV=1
-------HNYFLFFTNRGRVLRLKGHEIPESGRQARGTAIVNLLYKEYITTVIPIR-DYYLLMGTRNGVIKKSSLSDYDS-RR--DGI---IALNLDEGD
ALVNVL-T---DS-DDIIIGTKYGMAIRFAE--VRVTRTRGVRGITLR---GVVTMDRARDDSDLLVVTSNGYGKRSRLKDYRIQSRGGIGVTNIRCTNG
Y-VVSLHVIRE-EEVLMISSEGVMIRLKAGDISLIGRATQGVMLMKMGKG--DHVVAVARVV--------------------------------------
------------
>tr|H1XV71|H1XV71_9BACT DNA gyrase subunit A OS=Caldithrix abyssi DSM 13497 GN=gyrA PE=3 SV=1
-------HDYILIFTDRGKCYWLKVYAIPAGSRISKGRPIINLIDSEKIKAVLPVK-EHFILMATRKGLIKKTNLSAFSR-RK--SGI---IALNIREDD
ELIEAK-S---DG-RKVLYVTAHGKAIHFHE--VRPMRATGVRAIRLR--DRVIAMVVAN-EMDLLTISELGYGKRTPIKEFRQQSRGGSGIIGMKVTTG
Q-LVGALGVYN-QDIVIITVKGIINRQNTINISRYGRSTQGVRLIRLTEG--DRVSDVAKVS--------------------------------------
------------
>tr|A0A0Q1AQ60|A0A0Q1AQ60_9DELT DNA gyrase subunit A OS=Desulfuromonas sp. SDB GN=APR63_02575 PE=4 SV=1
-------HDYLLCFTDRGQLHWLRVYNIPEAARDARGRSLSNLLNKETVKAVISVKEDQYVFMATKKGIVKKCSLAEFSRPKK--MSI---RAISLSWDD
ELVEAN-T---NGKDDIVLVTTNGKTIRFDE--VRQFRARGVIGIRLD---DVVSMMSFDKDISILTACQHGYGKLTKITEYPTQHRGGKGVIGI--SNG
Q-VVISIPTQDDDGLILISQDGKVIRLAISDIRRIGRNTQGVRLMKLDN-G-DTLVGAAIIS--------------------------------------
------------
>tr|E6VSG3|E6VSG3_DESAO DNA gyrase subunit A OS=Desulfovibrio aespoeensis (strain ATCC 700646 / DSM 10631 / Aspo-2) GN=gyrA PE=3 SV=1
-------HQHLVLFTNLGKMFKIKAHQVPEGSRYAKGGHVANLL-KECITTALSLRDDRFFLFLTKKGMIKRSSIGLYGNCRS--TGI---RAVNLRDGD
ELMMVR-I---EPDVDCILVTRDGSAIRFNI--ARPLRTAGVKGVALR---DVVACVVTGDRDQLLTVSAGGFGKRTGIDQYRQQSRGGKGILNM--TTG
K-VVGARMVNESDDVILLTSANKIIRMSVSEVSQRGRATQGVRLVRMDA-N-NSVIGFELVM--------------------------------------
------------
>tr|A0A068JLN7|A0A068JLN7_9DELT DNA gyrase subunit A OS=Desulfonatronum thiodismutans GN=gyrA PE=3 SV=1
-------HNFILLFTNKGRMYKIKAYNIPEGSRTARGVHASNLL-KEFIATAMTIKTDKDFLFATKRGVVKRSQAQLYVNCRQ--SGL---KAVNLHPED
ELITVR-I---STSAEVVLITKHGKSIRFSS--IRSTRTAGVKGMDLN---DVVSCVVTDDREEVLTVSANGYGKRTLIENYRSQSRGGKGVINM--TTG
N-VVGSVLVQAEDDLLILTSAGKIIRMNVAGISRVGRDAQGVTLVRMDP-D-VSVVGFDRVD--------------------------------------
------------
>tr|F0JIQ5|F0JIQ5_DESDE DNA gyrase subunit A OS=Desulfovibrio desulfuricans ND132 GN=gyrA PE=3 SV=1
-------HQHLVLFTNFGKMFKIKVHQVPEGSRYAKGGHVNNLL-KEHIATCLSLRDDRFFLFVTKKGMIKRSSIGLYGNCRT--TGI---RAVNLRDHD
ELMDVR-I---EPEVDCILVSREGSAIRFNI--ARPMRTAGVKGMALR---DVVACVVTGDRDQLLTVSEGGYGKRTTIDQYRVQTRGGKGILNM--TTG
M-VVGACMVNESDDVILLTSQNKIIRMSVSEVSQRGRATQGVRLVRMDD-D-NKVIGFDLVM--------------------------------------
------------
>tr|D9TMD0|D9TMD0_THETC DNA gyrase subunit A OS=Thermoanaerobacterium thermosaccharolyticum (strain ATCC 7956 / DSM 571 / NCIB 9385 / NCA 3814) GN=gyrA
-------HDRLLFFTNKGKVYSLRTIDIPESGRQAKGTAIVNLIQQEKVSAVIPIK-AKYVVMCTKKGIIKKTEIDDFPK-KK--SGN---TAIKLDDGD
ELINVM-T---NG-REIIIGTANGYCIRFHE--LRPMRARGVIAISLR---DVVEMDLINEDNEILVVTENGYGKRSDVKEYRSQTRAGKGIIATKITTG
K-LVSIMSVSK-DELMIISANGILIRTRIADISKMHRDASGVTLMKLDDG--DRVVSTAKID--------------------------------------
------------
>tr|D7APY9|D7APY9_THEM3 DNA gyrase subunit A OS=Thermoanaerobacter mathranii subsp. mathranii (strain DSM 11426 / CIP 108742 / A3) GN=gyrA PE=3 SV=1
-------HDRLLFFTNKGKVYSLRTIDIPETGRQAKGTAIVNLIQQEKVTAVIPLK-IKYVVMCTKKGIIKKTSIEEFRS-KR--NGI---IAITLEEND
ELINTK-T---NG-REIIIGTAKGYAIRFNE--IRPMRAKGVIAISLR---DVVEMDLVHPGSEILVVTEKGFGKRTDLEEYRLQTRAGKGIIAIRLSTG
K-LVSIRSVNE-DEFMIISANGILIRMKVSEISKMHRDTRGVTLMKLDDG--DRVVSTARIE--------------------------------------
------------
>tr|B7R8A4|B7R8A4_9THEO DNA gyrase subunit A OS=Caldanaerobacter subterraneus subsp. pacificus DSM 12653 GN=gyrA PE=3 SV=1
-------HDRLLFFTNKGKVYSLRTIDIPESGRQAKGTAIVNLIQQEKVTAVIPLK-IKYVLMCTKKGIIKKTSIEEFKS-KR--NGI---IAITLDEND
ELINVK-T---NG-REVIIGTAKGYVIRFNE--VRPMRARGVMAISLR---DVVEMDLVHPDGEVLTVTEKGFGKRTDLEEYRIQGRAGKGIIAMKLSTG
K-LVSIRCVQE-DEFMIISANGILIRMKVKDISKMHRDTQGVTLMKLEDG--DRVVSTARIE--------------------------------------
------------
>tr|W9EC92|W9EC92_9FIRM DNA gyrase subunit A OS=Thermoanaerobacterium aotearoense SCUT27 GN=gyrA PE=3 SV=1
-------HDRLLFFTNKGKVYSLRTIDIPESGRQAKGTAIINLIQQEKVNAVIPVK-AKYVVMCTKNGIIKKTEIEDFPK-KK--SGN---TAIKLDDGD
ELINVM-T---DG-REIIIGTANGFCIRFHE--LRPMRARGVIAVTLR---DVVEMDLVDRDRDILVVTENGYGKRSDADEYRLQTRAGKGIIAAKITTG
K-LVSIMSVSK-DELMIISANGILIRTKIADISKMHRDTAGVMLMKLDEG--DRVVSTARIA--------------------------------------
------------
>tr|T1ZUR1|T1ZUR1_STRAP DNA gyrase subunit A OS=Streptococcus anginosus C1051 GN=gyrA PE=3 SV=1
-------HDHLLFFTNKGRVYRLKGYEIPEYGRTAKGLPIVNLLKDETIQTIINVQ-DSYLFFTTRYGVVKRTSVTEFAN-RQ--NGL---KALNLKDED
ELINVF-T---NG-ADIIIGTKMGYAVRFNE--VRNMRATGVRGVNLR---GVVGASVISDDQEVLVITEKGYGKRTLASEYATKSRGGKGMKTANITNG
P-LAGLMAVND-EDLMIITNTGVIIRTNVANISQTGRATLGVKVMRLDKG--AQIVTFTSVA--------------------------------------
------------
>tr|R5X4Z9|R5X4Z9_9FUSO DNA gyrase subunit A OS=Fusobacterium sp. CAG:649 GN=gyrA PE=3 SV=1
-------LDTIMVFTDRGKVYNIRAYEIPDS-RQSRGRLLSNIINEEKVRDTIVIK-EKEVVFITKNGLIKKTSLGEFKNINN--SGL---IAIKTKEDD
DIIFVGLI---EDKEEILIATHDGYCTRFL---IRATRTQGVKAITLR---MVVSAMLIKNETDILTITENGYGKRTSLDEYPQYNRGGKGVINLKVNTG
K-VVSVLEVS-DEELMCITSNGIVIRTSINEISR-GRATQGVRIMKVAD-D-EKVAATTKIK--------------------------------------
------------
>tr|B6G1U2|B6G1U2_9FIRM DNA gyrase subunit A OS=[Clostridium] hiranonis DSM 13275 GN=gyrA PE=3 SV=1
-------HSRLLFFTNRGRVFRLNAYEIPEGKRQAKGTAIVNLLQPEKIATLIDVDENKYLLIATKKGMVKKTKISDFKN-NK--SGL---ISIGLKEGD
EVIGVK-T---DG-QDVMLVTRNGMSIRFSE--VRGMRAMGVKGITLG---GVVSMSLASEGTDMLVVSENGFGKRTDLEEYRSQIRAGKGIKTYNISTG
S-IVGAEMVAD-DEMMIINSDGVLIRIKVNEISIFGRVTSGVKLMNVDEE--VSIVSIAKIT--------------------------------------
------------
>tr|R5X9R8|R5X9R8_9CLOT DNA gyrase subunit A OS=Clostridium bartlettii CAG:1329 GN=gyrA PE=3 SV=1
-------HNRLLFFTNRGRVFRLDAFEVPEGKRQAKGTAIVNLLQPEKIATLIEVDDDSYLLLATKKGIVKKTKRSEFKN-NK--SGL---IAIGLRDDD
ELIDVK-T---NG-KDVLLVTSNGMSIRFDE--IRPMRAMGVKGITLS---GVVSMSLSDEGEDLLVVSQNGYGKRTDINEYRSQIRAGKGIKTYNMSTG
E-IVGATMVNE-DELMLINSDGVLIRLRVDDISVFGRITSGVKLMKTDDE--VNVVSIAKID--------------------------------------
------------
>tr|A0A0L0W7N5|A0A0L0W7N5_CLOPU DNA gyrase subunit A OS=Clostridium purinilyticum GN=gyrA PE=3 SV=1
-------HDNILFLTNQGRVYRLKAYEIPEAKRQAKGTAIVNLLQPEKVTAVIPIK-DDYLTLVTEKGIIKKTKLDKFGN-RK--NGL---IGISLKEDD
ELISAK-T---NG-NDIILVTSYGMSIRFNE--VRDMRAGGVKAITLK---GIVGMDLIEEGKDLLVISERGYGKRTKISSYRIQTRGGKGLKTYNIKTG
K-LISAKIVDE-DEVMLISLSGTIIRLKVSDISRMGRTTQGVRLMKTDKD--DRVVSVAKVI--------------------------------------
------------
>tr|T2GA48|T2GA48_DESGI DNA gyrase subunit A OS=Desulfovibrio gigas DSM 1382 = ATCC 19364 GN=gyrA PE=3 SV=1
-------HQTLLLFSNKGRMYSVKVHQVPEGSRTAKGMHIANLL-REWIATALTMRETRALLFVTRKGVVKRSEATLYSNVRR--AGI---IALNLREDD
ELIMVR-V---GDTDECVLTTQKGLAIRFPV--VRLMRSAGVKGMTLA---DVVAGVILKAVQEILSISSNGYGKRTLIEHYRLQSRGGKGVINM--TTG
D-VIGAMPVSESDELILLTTANKAIRTSVREISLVGRATQGVRIVRMDE-K-DSVAAFDLVR--------------------------------------
------------
>tr|C7M119|C7M119_ACIFD DNA gyrase subunit A OS=Acidimicrobium ferrooxidans (strain DSM 10331 / JCM 15462 / NBRC 103882 / ICP) GN=gyrA PE=3 SV=1
-------LSRLLVFSSRGRVYQLRGYELPKLERSARGTALVNLVPDERITSVMGTKEDADLVFFTRNGMVKRTAMAEYARSRR--DGI---IAIDVRGDD
ELVSVVVA---TEEHDGVVFTKRGQVLRFPL--VRRTRTAGVRSIRRA---WIVAGGLI--GVEVLLVTSRGYGKRTPLDSFPVHHRGGAGIRGI--TKG
E-LVAAAFVRPEDEVLIVSSQGQMIRVRIGDISNQGRYATGVKLISLQA-E-ESVASVGVVP--------------------------------------
------------
>tr|A0A0R2QHY3|A0A0R2QHY3_9ACTN DNA gyrase subunit A OS=Acidimicrobiia bacterium BACL6 MAG-120924-bin43 GN=ABR75_04775 PE=4 SV=1
-------HAYLLFFSNRGRVYRLRALEIPERERTAKGIPIVNLLPPETIQAIIDTRGERFLFFATKQGQVKKTAFDEYNSSRR--DGL---IALKLRPKD
ELVRVIET---SGTDDVFMVTKGGQTIRFAE--VRPMRAAGVRGMKLR---EVVALDIA--DSAILLITESGYGKRTQLTNFARKGRGGLGMIGI--TKG
S-VVAAFMVGLEDDIVVVASGGTTIRTPVKEISSQGRAATGVRIMSLGT-G-QVVASAALVL--------------------------------------
------------
>tr|B3ESJ9|B3ESJ9_AMOA5 DNA gyrase subunit A OS=Amoebophilus asiaticus (strain 5a2) GN=gyrA PE=3 SV=1
-------HQYLLIFTTLGKVFWKKVYTLPEGSKSSKGRAIQNLIPPDQVQSVIKVRNSRYILMCTVQGVIKKTPLDAYIN-RT--NGI---QAIKINEGD
RLLTVKLT---KGDNHVIIALRSGRAIHFH---VRSMRSTGVRGITLAP--DVVGMVTVYKDIELLVVAEKGVGKRSAVADYRITKRGGKGVKTLNITTG
A-LAAIEAVT-ADELLIINTSGIAIRIEVSTLRIMGRNTQGVRLIRLNE-G-DAITSIAKIT--------------------------------------
------------
>tr|T0IPH5|T0IPH5_9FIRM DNA gyrase subunit A OS=Sporomusa ovata DSM 2662 GN=gyrA PE=3 SV=1
-------HHNLLFFTSRGRMYRLKGYELPEAGRTAKGTAIVNLLQKEKITAVIPIK-KRYLFMATQKGTVKKSELLEFDT-RK--GGL---IAISLDEDD
DLIGVK-T---NG-YDIIMGTRDGKAIVFHE--VRIMRAHGVKGITLD---DVIGMDVVKKDGEVLTITSEGYGKRTNANDYRITGRGGKGVINIKPAIG
Y-VIGIKIVKG-QELMLITSEGIVIRMEIDTISITSRSTQGVKVMRTDAE--DKVVALAVVE--------------------------------------
------------
>tr|A0A0K8JJ17|A0A0K8JJ17_9FIRM DNA gyrase subunit A OS=Propionispora sp. Iso2/2 GN=gyrA PE=3 SV=1
-------HNNILFFTSRGRVYKLKGYEIPEASRTARGTAIVNMLAQEKITAVIPVK-RRFLLMVTQKGIVKKTELMEFDT-RK--GGL---IAINLDDDD
DLIGVR-T---SG-HYVIIGTKGGLAIYFPE--VRPMRAHGVKGITLQ---GVVGMDTVKKDGELLTVTSEGYGKRTPLVEYRNQSRGGKGVINIKVTTG
H-VVGIKVVKG-QELMLITGDGIVIRTDIDAISVFSRNAQGVKIMRTGET--DTVVALAVVE--------------------------------------
------------
>tr|I9AXI5|I9AXI5_9FIRM DNA gyrase subunit A OS=Pelosinus fermentans B4 GN=gyrA PE=3 SV=1
-------HHNILFFTNRGRVYRLKGYEIPEASRTSKGTSIINLLPGERITAVIPIK-TRYLFMATAKGIVKKTELMDFDT-RK--TGL---IAITLDEDD
DLIGVK-T---NG-QYVLMGTQDGLAIYFPE--VRDMRARGVRGIRLH---GVVGMDTLKQEGEVLTVTAEGYGKRTPVDSYRNQKRGGKGVINTKVTTG
Q-VVGIKVVRG-QELMLISSEGIVIRIDIDTISVISRNTQGVKLMKTGEN--DKVVALAAVE--------------------------------------
------------
>tr|F7NQC7|F7NQC7_9FIRM DNA gyrase subunit A OS=Acetonema longum DSM 6540 GN=gyrA PE=3 SV=1
-------HHNILFFTNQGRVYRLKGYEITDAGRTAKGTAIVNLVPGELITAVIPVK-QRYLFMTTRNGIVKKTEVIEFDT-RK--GGL---IAIILDEGD
DLIAVK-T---NG-QEVIIGTSEGIAIRFSE--VRTMRSRGVKGISLE---TVIGMEVATKGTEIMTVTAEGYGKRTAVDEYRVQTRGGKGVINHKVTTG
Q-VIGIKMIKG-QEIMLISTDGIIIRMEADEIPTQGRSTQGVRMMRIGEN--DKVGALAVVD--------------------------------------
------------
>tr|M1ZFI8|M1ZFI8_9FIRM DNA gyrase subunit A OS=[Clostridium] ultunense Esp GN=gyrA PE=3 SV=1
-------HDTILFFTNKGRVYSLKAYEIPER-RQARGTAIVNLLNGESISAVIPIEPKSNLVFITKNGLIKKTKLSNFKN-RR--NGI---IAISLKEED
ELIAVR-T---NG-RQIIVVTSMGMSIRFSE--VREMRAMGVIAIRLK---DVVAMDLIEE-KDLLVVSEFGFGKRTPLDEYRIQNRGGVGIKTYNVKTG
K-LVSAKVTDN-DEIIMISMSGIIIRLISKGISSMGRNTQGVTLMKINNEN-DKVMAVAKYV--------------------------------------
------------
>tr|Q83VM8|Q83VM8_STRSU DNA gyrase subunit A OS=Streptococcus suis GN=gyrA PE=3 SV=1
-------HDHLLFFTNKGRVYRLKGYEIPEYGRTAKGLPVVNLLKEESIQTIINVT-DHYLFFATRQGIVKRTNVNEFSN-RQ--NGL---KALNLKDDD
ELINVF-T---DG-ADVIMGTKFGYSVRFAE--VRNMRATGVRGIKLR---GLVGATIVSDDQEVLVLSENGYGKRTPASEYPTKGRGGKGIITLKVANG
P-LAGLTTVQD-EDIMVITDTGVIIRTSIANISQTGRSTMGVKVMRLDEE--AKIMTFALVD--------------------------------------
------------
>tr|F9HEI1|F9HEI1_9STRE DNA gyrase subunit A OS=Streptococcus sp. oral taxon 056 str. F0418 GN=gyrA PE=3 SV=1
-------HDRLLFFTNKGRVYRLKGYEIPEYGRTAKGLPIVNLLKDETIQTIINVE-DSYLFFTTRHGVVKRTSVTEFSN-RQ--NGL---RALNLKEDD
ELINVF-T---DG-ADVIIGTKYGYSVRFNE--VRNMRATGVRGVNLR---GVVGAGVISDTDEVLVITEKGYGKRTLASEYPTKGRGGKGIKTANITNG
Y-LAGLMTIKE-EDLMIITNTGVIIRTNVANISQTGRATLGVKVMRLDQN--AQIVTFTTVE--------------------------------------
------------
>tr|E8UAE8|E8UAE8_DEIML DNA gyrase subunit A OS=Deinococcus maricopensis (strain DSM 21211 / LMG 22137 / NRRL B-23946 / LB-34) GN=gyrA PE=3 SV=1
-------HDYLLFFTDQGRLFHEKIYDLPEAGRDAKGTHIKNLLP-ESVASVLAIKEAGSFVFATKRGMIKKTQIRDYGNITS--AGL---IALNLQDDD
GLIGVG-Q---RDGDHIVLATSDGQAMRFGA--VRDTRTQGVIGIRLR---HVVSMAVVPGDSELLAISECGLGKRTPVSDYPSKGRGGLGVITL--TTG
K-LVALARVAGDEELMVLTQKGTVIRTRVEEVRVTGRNAQGVKIINLGD-G-DCVISAFPIR--------------------------------------
------------
>tr|F0RM54|F0RM54_DEIPM DNA gyrase subunit A OS=Deinococcus proteolyticus (strain ATCC 35074 / DSM 20540 / JCM 6276 / NBRC 101906 / NCIMB 13154 / VKM A
-------HDYMLFFTDQGRLFHEKIYDLPEAARDAKGSHIRNLLP-ENIASVQSIREEGSFVFATKNGMVKRTLITDYGNITS--AGL---IAINLQEDD
ELISVG-V---KNGSDIVLATRGGKAMRFAA--VRDTRTQGVIGIRLK---RVVSMALVPAESELLAISEHGLGKRTPVSDYPSKGRGGQGVITL--TTG
R-LVTLARVDGGEELMVLTQGGLVIRTRVEEVRVTGRNAQGVKVINLSD-K-DRVISAFPIR--------------------------------------
------------
>tr|G5KFV1|G5KFV1_9STRE DNA gyrase subunit A OS=Streptococcus urinalis 2285-97 GN=gyrA PE=3 SV=1
-------HDHVYFMTNKGRVYRLKGYEIPEYGRSAKGLPIVNLLKDETIQTIISEK-ENYFFFVTKHGVVKRTKESEFRN-RQ--NGL---KALGLKEGD
ELINVF-T---NG-DDIIIGTKLGYSVRFNE--VRSMRATGVRGVKLR---EVVSAARITDSQEVLVITENGYGKRTAATEYPTKGRGGKGIKTANITNG
P-LAGLLTVND-EDIMIITNTGVIIRTNVANISQTGRATLGVKVMRLDQE--SKIMTFTLVD--------------------------------------
------------
>tr|S8HQN4|S8HQN4_STRAG DNA gyrase subunit A OS=Streptococcus agalactiae FSL S3-170 GN=gyrA PE=3 SV=1
-------HDTVLFFTNLGRVYRLKAYEIPEYGRTAKGLPIVNLLKDETIQTIINAR-NKYFFFTTQQGIVKRTSVSEFSN-RQ--NGL---RAINLKEND
ELINVL-I---DE-EDVIIGTRTGYSVRFKV--VRNMRATGVRGVNLR---GVVGASRIVNGQEVLIITEKGYGKRTEASEYPTKGRGGKGIKTANITNG
P-LARLVTINN-EDIMVITDTGVIIRTNVANISQTGRSTMGVKVMRLDQE--AKIVTVALVE--------------------------------------
------------
>tr|U5PBA1|U5PBA1_9STRE DNA gyrase subunit A OS=Streptococcus sp. I-G2 GN=gyrA PE=3 SV=1
-------HDRLLFFTNKGRVYRLKGYEIPEYGRTAKGLPIVNLLKDESIQTIINVA-DAYLFFTTRSGLVKRTSVAEFAN-RQ--NGL---KALNLKDED
ELINVF-T---DG-ADVIIGTKFGYSVRFKE--VRNMRATGVRGVNLR---GVVGASVITDQDEVLIITEKGYGKRTRADEYPTKGRGGKGIKTANVANG
P-LAGLMTVKD-EDLMIITNTGVMIRTSVANISQTGRSTMGVKVMRLDQD--AQIVTFTTVQ--------------------------------------
------------
>tr|J9HWJ0|J9HWJ0_9BACL DNA gyrase subunit A OS=Alicyclobacillus hesperidum URH17-3-68 GN=gyrA PE=3 SV=1
-------HDYLLFFTNRGRMYAIKAYDVPEFSRQARGIPIVNLLNQEKINAVIPVKEGINLVFATRQGIVKKTPLSEYSN-RK--NGL---IAINLRDDD
DVVGVK-T---DG-KEIMMVTRQGLAIRFPE--VRPMRATGVKGISLG---KVIAMDVAEDDHDVLVVTSRGYGKRTPVQEYRAQSRGGKGIKTINCTNG
Q-AIEMCMVTD-DDLMIISQSGVAIRIHVRDISTQSRNTQGVRLINVDEG--QEVASVSRVV--------------------------------------
------------
>tr|A0A0P9CHI8|A0A0P9CHI8_9BACL DNA gyrase subunit A OS=Alicyclobacillus ferrooxydans GN=AN477_17350 PE=4 SV=1
-------HHYLLVFTNKGRMYSLKAYEIPEYSRQAKGLPIINLLQSEKISTVIPVREDMKLFFATRQGIVKKTALKEYAN-RK--NGL---IAINLREDD
QLISVR-T---DG-KDIIMATSRGMSIRFPE--VRQMRSTGVKGIQLS---DVIGMDVVEPENDVLVVTSRGYGKKTHVSDYRVQARGGKGIKTLNCTNG
I-VVGLKMVQD-DDLMIITNAGVAIRIHVADISTQSRNTQGVRLINVPEG--EEVATVARVI--------------------------------------
------------
>tr|A0A094K3Z8|A0A094K3Z8_9BACL DNA gyrase subunit A OS=Thermoactinomyces sp. Gus2-1 GN=gyrA PE=3 SV=1
-------HSTLLFFSNKGKVYRLKAYEVPELGRTAKGTPVINLIQQERIEAVIPVKPNQFLFFVTAEGVVKKTALSEFEN-RR--NGL---FAINLRDGD
DLVGVR-T---DG-QEVIMGTRHGMSIRFHE--VREMRATGVKGITLG---GIIDMDIVVPDSYVMIVTENGYGKRTPIDEYRIQSRGGKGIKTLSLTKG
E-VVAHKVVSN-EDLMIATQSGVVIRIKVADISIMGRYAQGVRLIRVDED---EVSAVARVH--------------------------------------
------------
>tr|F8IHM2|F8IHM2_ALIAT DNA gyrase subunit A OS=Alicyclobacillus acidocaldarius (strain Tc-4-1) GN=gyrA PE=3 SV=1
-------HDYLLFFTNRGRMYAIKAYDVPEFSRQARGTPIVNLLNQEKVTAMIPVKGDTYLFFATRQGIVKKTPLAEYSN-RK--NGL---IAINLRDDD
DLVGVK-T---DG-KEIMMVTRNGLAIRFPE--VRPMRATGVKGISLS---GVIAMDVAEDDHDVLVVTSRGYGKRTPVSEYRAQSRGGKGIKTLNCTNG
H-AIEMCMVTD-DDVMIVTQAGVAIRIHVRDVSTLSRNTQGVRLINVDEG--VEVASVSRVV--------------------------------------
------------
>tr|A0A0N0YB50|A0A0N0YB50_THEVU DNA gyrase subunit A OS=Thermoactinomyces vulgaris GN=gyrA PE=3 SV=1
-------HNHLLFFSNKGKVYRLKAYEVPELGRTAKGTAIINLIQQERIQAIIPVKANQYLFFGTAEGVVKKTALSEFEN-RR--NGL---FAINLRDGD
ELIGVR-T---DG-QEVIMGTRGGMSIRFPE--VREMRATGVKGITLG---DVIDMDIVIPDKNVMIVTRNGYGKRTPMEEYRVQSRGGKGIKTLSLTKG
D-VIGHKVVSD-EDLMIVTQSGIVIRLNVNEISIMGRYAQGVRLIKLDDD---EVAAVAKVN--------------------------------------
------------
>tr|T0C129|T0C129_9BACL DNA gyrase subunit A OS=Alicyclobacillus acidoterrestris ATCC 49025 GN=gyrA PE=3 SV=1
-------HDYLLFFTNRGRMYAIKGYEVPEFSRQARGIPIINLLNQEKITAVIPVQSGINLFFATRHGIVKKTALSEYSN-RK--NGL---IAINLRDDD
DVIAVK-T---DG-KNIMMVTRLGLAIRFNE--VRAMRATGVKGISLN---DVIAMDVAEDDHDVLVVTANGYGKRTPVTEYRGQMRGGKGIKTMHCTNG
N-VIEMRMVTE-DDLMIITQSGVAIRIHVKDISTQSRNTQGVRLINVAEG--DEVATVSRVM--------------------------------------
------------
>tr|R7CPX9|R7CPX9_9FIRM DNA gyrase subunit A OS=Dialister sp. CAG:357 GN=gyrA PE=3 SV=1
-------HNRILFFTNKGKVYMKTAVEFPKG-RTARGSALINFIPPERVTELLDIDDMKYLLMVTKKGYIKKTEISEYKNINK--NGL---IAVRLNDGD
RLVTVLAV---KGDEEIIIGTRQGMAIRFSI--VRTMRTAGVHAIRLSDG-EVVGAVLAT-DKDIFTISADGNAKRNKSSAYH-QGRNGRGVRNFKKG-Y
E-VVALVAAD-NDELVGVSEQGITIKTKASQISSKARAGQGVILQRLED-G-DRIASIDVIS--------------------------------------
------------
>tr|E4L7C9|E4L7C9_9FIRM DNA gyrase subunit A OS=Dialister microaerophilus UPII 345-E GN=gyrA PE=3 SV=1
-------HNRLLFFTDEGKVYLKSVIEFPLS-RTARGSALINFIPKERVTEMLDPDGVKYLLMITRYGYVKKTLIEEYKHINK--NGI---IALRLNEGD
RLVKVIPV---VGDEDVILGTRKGMAIRFSI--IRSVRAAGVHGIKLS---EVVGAVIAD-EKDIFTISADGNAKRNKESAYH-QGRNGKGVRNFKRG-F
E-VVALVAAD-NDELVGVSEGGITIKTSASQISSKAKAGQGVILQRLEE-G-DRIASIDVVP--------------------------------------
------------
>tr|R7PRJ8|R7PRJ8_9FIRM DNA gyrase subunit A OS=Dialister sp. CAG:588 GN=gyrA PE=3 SV=1
-------HHRILFFTNTGRVYMRSAFDIPENNRNSKGSALINFIPPEKVTELFDVDTAKYLFMVTKKGFVKKTETVEYKNIRQ--NGL---IAVKLREGD
SLVTVHHV---AGGEKVFLATKDGMGICFP---VRAMRTGGVRGIDLK---EVIGAVIAEEGKDIITISSDGQAKRNPISSYR-QSRNGKGTRNFKRG-Y
E-VVAVVTAA-DDELVGVSEKGVTIKVRVADITAKSRGSQGVSIQNLEE-G-DRVASIDNIP--------------------------------------
------------
>tr|C9LNG8|C9LNG8_9FIRM DNA gyrase subunit A OS=Dialister invisus DSM 15470 GN=gyrA PE=3 SV=1
-------HDRILFFTNKGKVYMKTAYDIPES-RTARGSAMINFITAEHVTELLDLDGTKYLLMVTKYGYIKKTALEEYKNINK--NGL---IAMRLKDED
RLVAVLPV---KGNEEIIMGTRKGMAIRFSI--VRPLRASGVHGMRLK---DVVGVVVAA-EKDIFTISADGNAKRNAASAYR-QGRNGQGTINFKKG-Y
E-VVALVAAD-RDELVGISEQGITIRIPADQISSKAKGGQGVILQRLEE-G-DRIASIDVVS--------------------------------------
------------
>tr|R6A4A0|R6A4A0_9FIRM DNA gyrase subunit A OS=Dialister sp. CAG:486 GN=gyrA PE=3 SV=1
-------HNRILFFTNKGKVYMKTAVEFPKT-RTARGSALINFIPRERVTELLDIDGTKYLLMVTKKGYVKKTELAEYKNINK--NGL---ISIRLNEGD
RLAAVLAI---TGEEEIILGTKDGMAIRFSV--VRSMRAAGVHGIKLA---EVVGACIAA-DKDIFTISADGNAKRNKASAYH-QSRNGKGIRNFRRG-Y
E-VVALVAAD-KDELVGVSEQGITIKTKASQIVSKTKAGQGVILQRLED-G-DRIASIDVLS--------------------------------------
------------
>tr|I3QG60|I3QG60_9FLAO DNA gyrase subunit A OS=Blattabacterium sp. (Blaberus giganteus) GN=gyrA PE=3 SV=1
-------HQYLLFFTEKGKCFWLRVYEVPEGTKISKGRAIQNIIHEDKVNAYILTGKDYYVMMITQKGIIKKTSLESYSRPRK--YGI---NAIVIRKGD
SLLEAILT---KGRLTNFIAVKSGRIIRFSE-KVRSTRSSGVIGININEM-MVIGMICVDIKGQLLVVSEKGFGKRSHIKDYRITNRGGKGIKTI--TTG
S-LISIKYVTDQDDLMIIKKSGIIIRIPVSDIRVMGRTTQGVRLIHLKE-N-DFNEIP------------------------------------------
------------
>tr|G7SPS2|G7SPS2_9FLAO DNA gyrase subunit A OS=Blattabacterium sp. (Mastotermes darwiniensis) str. MADAR GN=gyrA PE=3 SV=1
-------HQYLLIFTEKGKCFWLRVYEIPEGSKISKGRAIQNMIHPDKVNAYILTGKNHYVMMVTQKGMVKKTSLKHYSR-RK--DGI---KAIVIREGD
SLLEAILI---KGNSHIFIAVKSGKIIRFS---VRSTRSSGVIGINLTP--DVIGMICLEKGQHLLVVSDKGFGKRSNLK-YRITNRGGKGIKTINITTG
S-LIAIKKVT-QDDLMIIKKSGIIIRIPVSDIRVMGRDTQGVKLINLKK-N-EEIADVEKVY--------------------------------------
------------
>tr|D0J8V5|D0J8V5_BLASP DNA gyrase subunit A OS=Blattabacterium sp. subsp. Periplaneta americana (strain BPLAN) GN=gyrA PE=3 SV=1
-------HQYLLFFTEKGKCFWLRVYEIPEGSKISKGRAIQNMIHPDKVNAYILTGQNHYVMMVTQKGIIKKTSLENYSR-RK--DGI---NAIVIRKGD
SLLEAILT---KGNSHVFIAVKSGKIIRFS---VRATRSSGVRGINLSS--DVIGMICVEGGY-LLVVSEKGFGKRTNLK-YRITNRGGKGIKTINITTG
S-LISIKHVT-QDDLMIIKKSGIIIRISVSDIRVMGRDTQGVRLINLKE-K-DEIADVEKVS--------------------------------------
------------
>tr|M4ZSW1|M4ZSW1_9FLAO DNA gyrase subunit A OS=Blattabacterium sp. (Panesthia angustipennis spadica) str. BPAA GN=gyrA PE=3 SV=1
-------HQYLLFFTEKGKCFWLKVYEIPEGSKISKGRAIQNIIRTDKVNAYILTGKDYYVMMITKKGIIKKTPLENYSRPRK--DGI---NAIVIRKGD
SLVEAILT---KGDSHVFVAVKSGRIIRFSE-KIRSTRSSGVIGINIK---MVIGMICV--KGHLLVVSEKGFGKRSSIKDYRITNRGGKGIKTI--TTG
S-LISIKYVTDRDDLMIIKKSGIMIRIPISDIRVMGRTTQGVRLIHLKE-N-DAIADVAKVY--------------------------------------
------------
>tr|D0JBG1|D0JBG1_BLASB DNA gyrase subunit A OS=Blattabacterium sp. subsp. Blattella germanica (strain Bge) GN=gyrA PE=3 SV=1
-------HQFLLFFTEKGKCFWLRVYEIPEGSKISKGRAIQNIIHQDKVNAYILTGKDYYVMMVTQKGIIKKTSLENYSRPRK--DGI---NAIVIRKGD
SLLEAILT---KGDSHVFIAVKSGRIIRFSE-KVRSTRSSGVIGIHFT-K-MVIGMICVDGKGHLLAVSEKGFGKRSNLKDYRITNRGGKGIKTI--TTG
Y-LIAIKHVTDQDDLMIIKKSGIIIRISVSGIRVMGRTTQGVRLINLKE-N-DAIADVAKVY--------------------------------------
------------
>tr|D4G392|D4G392_BACNB DNA gyrase subunit A OS=Bacillus subtilis subsp. natto (strain BEST195) GN=gyrA PE=3 SV=1
-------HDTILFFSNKGKVYRAKGYEIPEYGRTAKGIPIINLLEKEWINAIIPVTAELYLFFTTKHGVSKRTSLSQFAN-RN--NGL---IALSLREDD
ELMGVR-T---DG-KQIIIGTKNGLLIRFPE--VREMRAAGVKGITLT--DDVVGMEILEEESHVLIVTEKGYGKRTPAEEYRTQSRGGKGLKTAKITNG
Q-LVAVKATKE-EDLMIITASGVLIRMDINDISITGRVTQGVRLIRMAE-E-EHVATVALVE--------------------------------------
------------
>tr|A0A0Q0UEJ5|A0A0Q0UEJ5_9BACI DNA gyrase subunit A OS=Geobacillus sp. PA-3 GN=gyrA PE=4 SV=1
-------HDTVLFFTNKGKVYQAKGYEIPEFGRTAKGLPIINLLEKEWINAMIPIEDERYLVFSTKQGIAKRSSLSSFAH-RN--NGL---IAIHLREGD
ELISVR-T---DG-KHLIIGTKNGMLIRFPE--VRTMRATGVKAITLD--NDVVSMEILEDHHDVLVVTKKGFGKRTPASEYRVQSRGGKGLKTCNVTNG
S-VVAVTTVVN-EDLMVITTSGVLIRISVSDISRTGRVAQGVKLIRLSGEH-ECVATVAKVT--------------------------------------
------------
>tr|F5L548|F5L548_9BACI DNA gyrase subunit A OS=Caldalkalibacillus thermarum TA2.A1 GN=gyrA PE=3 SV=1
-------HDFILLFTNKGRVYRLKAYEIPELGRTARGLPIINLIQKEYITALIQVEPHRYLFFATRQGIVKRTALHDFEY-RR--GGL---FAINLRDND
ELISVR-T---DG-QEIIMGTKKGMAIRFSE--VRVMRAAGVKGITLR---DVIDMDVVKKDHDVMIVSRNGYGKRTSIDEYRIQSRGGIGLKSYNVTCF
E-VVGLKTVAN-DDFMLVTSSGLIIRIHVNEVSQLSRYARGVRLIRLQED--EEVATVAKVQ--------------------------------------
------------
>tr|E8K0E8|E8K0E8_9STRE DNA gyrase subunit A OS=Streptococcus infantis ATCC 700779 GN=gyrA PE=3 SV=1
-------HDHLLFFTNKGRVYRLKGYEIPEYGRTAKGLPVVNLLKDESIQTIINIE-DAYIFFTTRAGIVKRTSVKEFAN-RQ--NGL---KALNLKDED
ELINVL-T---QE-TDIIIGTKLGYAVRFNQ--VRSMRATGVKGVNLR---GVVGARVITDQDEVLIITEKGYGKRTVATEYPTKGRAGKGMKTANITNG
H-LAGLLTVKD-EDLMVITDTGVMIRTNVANISQTGRSTMGVKVMRLDEN--AKIVTFTTVA--------------------------------------
------------
>tr|A0A0A6VEN4|A0A0A6VEN4_9BACI DNA gyrase subunit A OS=Bacillus ginsengihumi GN=gyrA PE=3 SV=1
-------HDTILFFTNKGKAYRKKGYEIPEFGRTAKGIPIVNLLEKEWINTMIRVEENSYLFFTTRSGISKRTPLSDFAN-RT--NGL---IAIHLKEED
ELISVK-T---DG-KDIIIGTKNGMLIRFPE--VRSMRATGVKGITLS--NDVVGMEILEENNDVLIVTKNGYGKRTKEEEYRVQSRGGKGLKTCNITNG
P-LVAVKTVTE-EDLMLITAGGVMIRIAVDEISCLGRNTLGVKLIKLDE-D-GYVATVAKVE--------------------------------------
------------
>tr|V6IU74|V6IU74_9BACL DNA gyrase subunit A OS=Sporolactobacillus laevolacticus DSM 442 GN=gyrA PE=3 SV=1
-------HHHVLFFTNKGRVYQLKGYQIPEFGRTAKGIPIINLIQKEYITAFFPVEDDHFLVFLTKNGITKRSPLSDFSN-RK--GGL---FAITVRDED
ELIAVR-T---DG-RDLIVGTKKGMAIRYHE--VRAMRAAGVKAITLD--GDVVGMGIADEQLDVLIVTENGFGKRTAISEYRPQTRGGKGLKTCNITNG
E-LVALRTVEN-EDLMIMTANGVIIRMPVSGISKLGRNTMGVTLIRVDEGV-STIARIQSND--------------------------------------
------------
>tr|A0A0H4NUF1|A0A0H4NUF1_9BACI DNA gyrase subunit A OS=Bacillus smithii GN=gyrA PE=3 SV=1
-------HDTILFFTNKGKVYKTKGYEIPELGRTAKGIPIINVLGKEWINTMIAVEENWYLVFTTKHGITKRTPLREYAH-RT--NGL---IALTLREND
ELISVK-T---DG-QDIVIGTKNGMMIRFKE--VRSMRSTGVKGITLD--DDVIGMELLHDGEEVLIVTRNGYGKRTHEAEYRIQGRGGKGLRTCRITNG
P-LVAIKTISE-EDIMLMTAGGVLIRMDVQDISRTGRNAQGVKLIRLDE-D-EYVATVAVVE--------------------------------------
------------
>tr|S0KPK3|S0KPK3_9ENTE DNA gyrase subunit A OS=Enterococcus sulfureus ATCC 49903 GN=gyrA PE=3 SV=1
-------HDTLLYFTNAGKVYKSKGYEIPEYGRTAKGIPVINLLGDERIQAIVPVSEEEYLFFTTRLGVVKRTSVAAFSN-RS--NGL---IAIGLKEND
ELVNVL-T---KG-NTVIIGTHLGYSVTFTE--VRDMRAAGVRGIRLR---EVVGSAILREDSEVLVITENGYGKRTASQEYPLKGRGGKGIKTANITNG
P-LAGLTTVND-EDILMITNKGVIIRFNVASVSQTGRSTLGVRLMKMENG--AKVVTMATVE--------------------------------------
------------
>tr|F8L8Y4|F8L8Y4_SIMNZ DNA gyrase subunit A OS=Simkania negevensis (strain ATCC VR-1471 / Z) GN=gyrA PE=3 SV=1
-------HDYLMSFTNLGRCHWLKVWQIPEAGRRAKGRPLVNMLEEEHVAAVLRVR-DASILLATKRGVVKKTMIDSFSSPRR--KGV---FAINIDEGD
EVISAHVV---RKEQQVMLFTREGMAVRFDQ--VRPMRARGVRGVKLKA--AVVSCEVVKEDETVLVVCEHGYGKRSSVESFRQTHRGGVGVRSI--SNG
F-VVGALAVGDKDSVVLMSSSGHTLRLGMQDIRVMGRSTQGVKVVNLRE-P-DVLVAMQKIE--------------------------------------
------------
>tr|A0A0F9JLK2|A0A0F9JLK2_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_1437860 PE=3 SV=1
-------HDYLMIFTSLGKCYWLKVWQIPEAGRRTKGRPLINYIEKEKISTILKVR-GTYILLSTLKGVVKKTVVSLYGNIRK--KGV---NAINVDEGD
KLISAHLV---HDNDQIMLFTRNGMAVRFDE--VRAVRARGVKGVTLKP--YVVSTVVVKGTETILVVCENGFGKRSRVDTFRQTNRGGKGVRSI--SNG
L-VVGALSVQDEDGVFLMSQSGQSLRMRMKDLRVMGRSTQGVKLVALKA-N-DNLIDMQKIE--------------------------------------
------------
>tr|T0TZ90|T0TZ90_9STRE DNA gyrase subunit A OS=Streptococcus sp. HSISS2 GN=gyrA PE=3 SV=1
-------HDHLYFMTNKGRVYRLKGYEIPEYGRTAKGLPIVNLLKDETIQTVINAKENNHLVFVTRQGLVKRTKEAEFKN-RQ--NGL---IALKLREGD
ELINVF-T---TG-EEIIIGTKFGYSVRFKE--IRSMRAAGVKGVTLR---GVVGAAAIMDDQEVLIISEKGYGKRTSATEYPTKGRGGKGIKTANITNG
H-LAGIATVSN-EDIMVMTDTGVIIRTAVANISQTGRATQGVKVMRLDNS--ARIVTFALVE--------------------------------------
------------
>tr|A0A0M9AHJ3|A0A0M9AHJ3_9EURY DNA gyrase subunit A OS=Haloarcula sp. SL3 GN=gyrA PE=3 SV=1
-------HDYLLCFTNQGQVYRLKTYEIPEMSRTARGKSAINLIDDEELTAVVS--DDECITMVTRNGYVKRTCCSEFENILS--TGI---IAAKLEDGD
ELIDVD-T---DGTGDLVIATEAGMTIRFSE--VSEMRARGVNGIKLQ---DVAAMVATDDPRSLLTVTEHGFGKRTKLDEYRTQSRYGKGLIDI--DNG
R-VSTAKAVTDEDHLVIMSEQGQIMRIRAGDVSQVGRNTKGVTIMGLED-D-DRVASVTVVP--------------------------------------
------------
>tr|C7NZR8|C7NZR8_HALMD DNA gyrase subunit A OS=Halomicrobium mukohataei (strain ATCC 700874 / DSM 12286 / JCM 9738 / NCIMB 13541) GN=gyrA PE=3 SV=1
-------HDYLLCFTNQGQVYRLKTYEIPEMSRTARGKSAVNII-DEEITAVVSTD-DECLTMVTRNGYVKRTCVDEFENILS--TGI---IAAKLEDGD
ALVDVE-T---DDSGDLVVATEGGMTIRFDE--VREMRARGVRGIDLQ---DVAAMVATDDDRALLTVTENGYGKRTLLAEYSKQSRYGKGLIDI--DNG
R-VATAKAVREDDHLVIMSESGQIMRIPAGDVSQVGRNTKGVKIMALDG-V-DNVASVTVVP--------------------------------------
------------
>tr|I7J8J5|I7J8J5_METBM DNA gyrase subunit A OS=Methanoculleus bourgensis (strain ATCC 43281 / DSM 3045 / OCM 15 / MS2) GN=gyrA PE=3 SV=1
-------HDYLLCFTDKGRVYWLKVYDLPEGQRTSKGKAVVNLLNGERVTTVIPVR-DHYLFFATRGGTVAKMALDEFSR-RQ--TGI---NAINLRDGD
ELVDVK-T---DG-KELILTTRFGQSLRFHE--VRAVRAMGVRGIKLR--DTLQAISLVE-NDHLLTITEQGFGKRTEFDEFRGHGRGTMGVRNIVVDGG
G-VVGSRAVSD-DEIIVMSASGIVIRTKVEEISIQKRNTRGVRIMKLDD-G-DRVIGFTILD--------------------------------------
------------
>tr|A0A0J6ER67|A0A0J6ER67_9BACI DNA gyrase subunit A OS=Bacillus glycinifermentans GN=gyrA PE=3 SV=1
-------HDTLLFFSNKGKVYRAKGYEIPEFGRTAKGIPIINLLEKEWINAIIPVTDESYLFFTTKHGISKRTPLSQFAN-RN--NGL---IALSLRDED
ELMAVR-T---DG-KQIVIGTRNGLLIRFPE--VRQMRAAGVKGITLT--DDVVGMEILEEDADVLIVTENGYGKRTPASEYRTQSRGGKGLKTCKITNG
P-LVTVKATRE-EDLMIITASGVIIRMDINDISVTGRVTQGVRLIRLAD-Q-EHVSTVALVE--------------------------------------
------------
>tr|A0A0Q9XWZ3|A0A0Q9XWZ3_9BACI DNA gyrase subunit A OS=Virgibacillus soli GN=ACA30_22920 PE=4 SV=1
-------HDTILFFTNKGKVYRAKGYEIPEFSRTAKGLPIINLLGKEWINTVICVEEDWYLFFATKQGVIKRTPVSAFAN-RT--SGL---IALGLREND
ELISVK-T---DG-KDIIVGTKNGLLIRFNE--VRSMRATGVKGITLA--DDAVGMEILEEHEDVLVVTKNGFGKRTTAAEYRIQSRGGKGLITCKITTG
T-VVAVETVQD-EDIMIITDSGIVIRMDVEDISRIGRNTQGVKLMTLGD-D-SAVSTVAKVE--------------------------------------
------------
>tr|F7Z111|F7Z111_BACC6 DNA gyrase subunit A OS=Bacillus coagulans (strain 2-6) GN=gyrA PE=3 SV=1
-------HDTILFFTNKGKVYKKKGYEIPEYGRTAKGIPIVNLLEREWINTMIRVEEDWFLFFTTKKGISKRTPVTEFAN-RT--NGL---IAIHLKEED
ELISVK-T---DG-KEIIIGTKNGMLIRFPE--VRSMRATGVKGITLS--DDVVGMEILEENDDVLIVTKNGYGKRTKGSEYRIQSRGGKGLKTCNITNG
P-LIAVKTVTE-EDVMLITAGGVLIRMAVGDISVLGRNTMGVKLIRLGD-E-EYVATVAKVE--------------------------------------
------------
>tr|D6KJ74|D6KJ74_9FIRM DNA gyrase subunit A OS=Veillonella sp. 3_1_44 GN=gyrA PE=3 SV=1
-------HNTLLFFTSTGRAYRLKAYEVPEGSRNSRGTAMVNVLPVESVTTMIDLEEDVNLFMVTEFGVVKRTAIEEYRN-RR--SGL---NAINLDEGD
RLISVN-T---TG-QDILIGTKLGIAIRFSE--VRLMRAHGVRGIKLN---GVVGAGVLNT-AQVFTISEEGFGKRNDAEAYTLQKRGGKGSKNFKITTG
D-VVAVEVVHD-DEVMLISEQGKIIRFNMNDIAVKGKAISGVKTQNLDEGD-K-VASIAVIP--------------------------------------
------------
>tr|A0A096AIT1|A0A096AIT1_9FIRM DNA gyrase subunit A OS=Veillonella montpellierensis DNF00314 GN=gyrA PE=3 SV=1
-------HNTLLFFTSTGRSYRLKAYEVPESSRNSRGTAMVNVLPVEQVTTMINLE-DANLFMVTKYGVCKRTKIEEYQNIRR--SGL---NAINLDEGD
RLISVCMT---TGGQDILIGTKKGIAIRFN---ARLLRAHGVRGINLN---EVVGAGVFTGHVQIFTISEEGFAKRNDISAYTLQKRGGKGSKNFRITTG
D-VVAVEVVR-DDEVMIISEQGKIIRFNTTDIAVKSKAVSGVKTQNLD-SG-DKVASITVIP--------------------------------------
------------
>tr|F9N614|F9N614_9FIRM DNA gyrase subunit A OS=Veillonella sp. oral taxon 780 str. F0422 GN=gyrA PE=3 SV=1
-------HNTLLFFTSTGRAYRLKAYEVPESSRNSRGTAIINVLPVETVTNMIDLESDVNLFMVTKQGVVKRTAIDEYRN-RR--GGL---NAVALDEGD
QLISVG-T---YG-QDVLLGTKKGMAIRFHE--VRLMRARGVKGINLN---GVVGASIIHG-CQVFTISEEGYGKRNVESSYTVQKRGGKGTKNFKITTG
E-VVAVEIVNN-DEMMLISEQGKIIRFDVNDIAVKSKAISGVKTQNLD-EG-DKIASVAVIS--------------------------------------
------------
>tr|K9D2M6|K9D2M6_9FIRM DNA gyrase subunit A OS=Veillonella ratti ACS-216-V-Col6b GN=gyrA PE=3 SV=1
-------HNTLLFFTTAGRVYRLKGYEVPESSRNSRGTAIINVLPVETVTTMIDMEHSLNLLMVTKQGVVKRTSIEEYQN-RR--SGL---NAISLADDD
RLISVC-T---SG-QDVLLGTRKGMAIRFNE--VRLMRAQGVRGIKLN---GVVGAGVITE-CQVFTISEEGFGKRNSEDAYSLQKRGGKGTKNFRITTG
D-VVAVEIVTS-DEVMLISEQGKIIRFDMKDIAVKGKAISGVKLQNLE-GG-DKVASVAIIA--------------------------------------
------------
>tr|V4GUC3|V4GUC3_9EURY DNA gyrase subunit A OS=Candidatus Halobonum tyrrellensis G22 GN=gyrA PE=3 SV=1
-------HDYLLCFTTHGQVYQLKTYQVPEMGRTARGKSAVNVL-DEEITAVVNCD-EEYLTMVTRDGYVKRTAGEAFDNILS--TGI---RAIKLEEGD
ALADVE-T---HGDHHIVVGTRDGMAIRFAE--VRPMRARGVRGVRLT---DVAGVAAIDAHNWVLTVTKNGYGKRTDLDEYRVQSRNGKGLIDI--NNG
P-VCAVEAVTHGDHLFALSEGGQILRTPVEGISTYGRNTMGVRVMDLDA-G-DKVAAVDVLP--------------------------------------
------------
>tr|A0A0M5JAM5|A0A0M5JAM5_9BACI DNA gyrase subunit A OS=Bacillus gobiensis GN=gyrA PE=3 SV=1
-------HDTILFFSNKGKVYRAKGYEIPEFGRTAKGIPIINLLEKEWINAIIPVTDSSYLFFTTKQGISKRTTLSQFAN-RN--NGL---IALGLREDD
ELISVR-T---DG-KDIIIGTKDGLLIRFHE--VRQMRAAGVKGISLS--DDVVGMEILEEDSHVLIVTEKGYGKRTPAKDYRVQSRGGKGLKTCKITNG
S-LITVKATNE-EDLMIITASGVIIRMDINDISQTGRVTQGVRLIRLGE-Q-EHVATVALVE--------------------------------------
------------
>tr|B9K9M8|B9K9M8_THENN DNA gyrase subunit A OS=Thermotoga neapolitana (strain ATCC 49049 / DSM 4359 / NS-E) GN=gyrA PE=3 SV=1
-------TSSTLFITNFGKAYVLKNYQIETTGRNTRGKHISAFLNDERIVALVPLN-GKDLVIVTKSGKIKRTSLEEFENATSN-RGV---RAIRIEPGD
EIVSARST---SEKETLVVATKLGMIIRFPV--VRRMRAAGVQAIKLQ---EVVSMDVVP--GEILTVTEKGFGKRTPVQLYRVQKRGGTGLRNI--VTG
H-VVAVRYVKGDEEIVVVTRNGMMIRMPVSEIGVIGRVTKGVKLIELGD-D-TISKVAV-VK--------------------------------------
------------
>tr|D2C4U8|D2C4U8_THENR DNA gyrase subunit A OS=Thermotoga naphthophila (strain ATCC BAA-489 / DSM 13996 / JCM 10882 / RKU-10) GN=gyrA PE=3 SV=1
-------TASTLFITNLGRAYVLKNYQLETTGRNTRGRHITAFLNDEKIVALASLN-GNDLVIVTKSGKIKRTALKEFENATSN-RGV---RAIKIEPGD
EIVSARVN---SEKETLIVATKMGMAVRFPV--VRRMRAAGVQAIKLQ---EVVSVDVIPP-GEILTVTEKGFGKRTPVQLYRIQRRGGTGLRNI--VTG
Y-VVAVRYVRGDEEIVVVTRNGMMIRFPVSEIGVIGRVTKGVKLIELGD-D-TISKVAV-VK--------------------------------------
------------
>sp|C5CHA8|GYRA_KOSOT DNA gyrase subunit A OS=Kosmotoga olearia (strain TBF 19.5.1) GN=gyrA PE=3 SV=1
-------LSKTVVITSKGKAYFINNYELECTSRSSRGKLLANYVKPETVQAVLSVKANKHLIITTRKGKIKRTPFEAFINSRT--SGI---KAITLNEGD
SVVDAIST---SEEETIIISTRKGMVIRFPI--IRPMRAAGVKAMALR---EVVSATIVLPERYLFTATERGVGKRTPLSEYRPQHRAGMGVKNI--LTG
Y-VVGSLVVTNEDEIIVITKNGMSIRIPAADIRPTGRVTKGVKVVELRD-D-DTVASLAVVV--------------------------------------
------------
>tr|K7Z694|K7Z694_BDEBC DNA gyrase subunit A OS=Bdellovibrio bacteriovorus str. Tiberius GN=gyrA PE=3 SV=1
-------KTMLLVFTDKGKVYWCKVHRLPLGSRTSKGKSLANVVQNESVRAILPVN-NKYAVMLTEKGVIKKTSLDAFAN-RT--AGI---IALTTDLED
GVIDVK-S---DG-SDIFIATKEGMSIRFNE--VREMRARGVKAITLA--DVVVAMEVLEKKDTILMVTSKGYGKRSETGEYRIQSRGGVGIITQKTTVG
L-VIGTKKVAN-MELILSTDKGQVIRMKVTDISVLGRNTQGVRLINIDEKD-ETVTGVAVVA--------------------------------------
------------
>tr|M4V716|M4V716_9DELT DNA gyrase subunit A OS=Bdellovibrio exovorus JSS GN=gyrA PE=3 SV=1
-------KTMLLVFTDKGKVYWCKVHRLPMGTRTSKGKAIANVVQPEKVRAILPVN-NKNVVMLTEKGIIKKTTLDAFSN-RQ--AGI---IALTTDLDD
QVVAVS-S---DG-SDIFIATREGMSIRFNE--VRAMRARGVKGITLA--DVVVAMEVLEKPDTILMVTSKGYGKRSEVSEYRVQSRGGVGIITQKTTVG
N-VVGTKKVSL-HELILSTDQGQVIRMKISDISILGRNTQGVRLINLDEKQ-EFVKGIAVVA--------------------------------------
------------
>tr|U4T5M0|U4T5M0_9CHLA DNA gyrase subunit A OS=Chlamydia gallinacea 08-1274/3 GN=gyrA PE=3 SV=1
-------KDYLLIFTNFGQCYWLKVWQLPEGERRSKGKPIINFLESEKLAAVLNIK-G-FLFLATKQGLVKKVALEAFSNPRK--KGI---RALEIDDGD
ELIAANIT---SDEEKVMLFTRLGMAVRFPH--VRPMRARGVRGVSLKN--CVVACQIVEDSQSVLVVCNNGFGKRSQVSDFRETNRGGVGVRSI--NNG
N-VLGAISVADHDSILLMSGQGQAIRINMQDVRVMGRSTQGVRLVHLKD-G-DTLVAMEKLS--------------------------------------
------------
>tr|D7CQR2|D7CQR2_TRURR DNA gyrase subunit A OS=Truepera radiovictrix (strain DSM 17093 / CIP 108686 / LMG 22925 / RQ-24) GN=gyrA PE=3 SV=1
-------HDYLLFFTDRGRVYREKIYDLPEAERAARGSHLRNIL-EERVATVLSVRAEGYFVFATRQGMIKKTAIREYGNLNA--SGL---IAINLIEGD
ELVSVR-G---WDGAHVVLATREGQAIRFPE--VRDTRTQGVRGIRLK---DLVSLSVIAGDAELLAVTECGYGKRTPLSDYPVQGRGGQGVITL--TTG
P-LVSLDYVRGDEELLVLSEGGVLIRTRVGEVSRYGRPSQGVTIMRLGD-G-DRVVSVMVML--------------------------------------
------------
>tr|F2NLE8|F2NLE8_MARHT DNA gyrase subunit A OS=Marinithermus hydrothermalis (strain DSM 14884 / JCM 11576 / T1) GN=gyrA PE=3 SV=1
-------HDDLLFFTNKGRVYREKVFELPEASRQARGVHIRSIL-EEEVATLLSVRIPGHFVFATRRGLIKKTPIREYQNLTA--SGL---IAINLVDGD
TLIQVG-A---QEDAEVILATRNGQAIRFAL--VRATRSQGVRGVRLK---DVVSLIVVPKTGDLLAVGTRGYGKRTPVEEYPTQGRGGLGVLTF--TVG
Q-LAALLAVEGDEDLLVLSRRGLAIRTRVDQVAQYSRATSGVKIMNLQE-E-DEIAACFVIR--------------------------------------
------------
>tr|M5PVU2|M5PVU2_DESAF DNA gyrase subunit A OS=Desulfovibrio africanus PCS GN=gyrA PE=3 SV=1
-------HQYLLLFTNRGRMHQLKVHQVPEGGRYAKGSHIANLL-KEHVTTALTVREHNYFMFVTKRGMIKKTSASLYANVRS--SGV---RAVNLRDDD
ELIMVR-I---NGRDELILVTAEGTSIRFTS--IRPIRATGVKGIALR---DVVAGVVVRPRRLVLTISEKGYGKRTPVNQYRGQSRGGKGIINM--TTG
R-VVGAVVTYEKEEVILLTSGNKVIRLSSEDISVIGRATQGVRLVRMEE-E-DRVAAFDLIK--------------------------------------
------------
>tr|C4XT13|C4XT13_DESMR DNA gyrase subunit A OS=Desulfovibrio magneticus (strain ATCC 700980 / DSM 13731 / RS-1) GN=gyrA PE=3 SV=1
-------HQQLLLFTNLGRMFMLPVHQIPEGQRTAKGAHIANLL-KEFVATALSIREERYFLFVTRKGMVKRTCTDLYKNCRS--TGI---IAVGLKEND
ELLTVK-I---DDETEVLLATQQGLSNRFHI--VRPTRAAGVKGIALK---DVAAGVVITSRSEVLTVSANGYGKRTSIEHYPIRNRGGSGVINM--TTG
Q-VIGAVMVGDDDELLLLTSANKIIRLSVSGISSVGRATQGVMLVRMDE-N-DTVMGFDLVD--------------------------------------
------------
>tr|E1JVB4|E1JVB4_DESFR DNA gyrase subunit A OS=Desulfovibrio fructosivorans JJ GN=gyrA PE=3 SV=1
-------HQQLLLFTNLGRMFMLPVHQIPEGQRTAKGAHIANLL-KEFVATALAIRFERYFLFVTRKGMVKRSCTDLYKNCRS--TGI---IAVTLKEGD
ELLTVK-I---DDNAEVLLATNQGLSNRFHI--IRPTRAAGVKGIALK---DVAAGVIMTGRNEVLTISAHGYGKRTSIEHYPLRNRGGSGVINM--TTG
Q-VIGAVMVNADDELLLLTSANKIIRLSVSDISAVGRATQGVMLVRMEG-E-VTVTGFDLVD--------------------------------------
------------
>tr|S7TB88|S7TB88_9DELT DNA gyrase subunit A OS=Desulfovibrio alkalitolerans DSM 16529 GN=gyrA PE=3 SV=1
-------HQSLLLFTNQGRMHQLKVHRVPEGSRYAKGAHIANLI-KEYVATALSVREDRFFLFVTKRGMVKRTLASLYRNVRS--SGI---KAVLLRDDD
ELIMVR-I---DQTDEVVLCTREGTAIRFSV--VRPMRASGVKGIALR---DVMGAVIVPPWGHILTVAERGYGKRTAVGQYRLQSRGGRGVINM--TTG
K-VLGAILVQDDDQLVMMTSANKVIRIGVRDVSVVGRATQGVRLAALDN-G-GVLAAFDLVR--------------------------------------
------------
>tr|S7U4U7|S7U4U7_9DELT DNA gyrase subunit A OS=Desulfovibrio sp. X2 GN=gyrA PE=3 SV=1
-------HQSLLLFTNLGRMHQLKVHRVPEGSRYAKGAHIANLV-KEHIATAMSVREDKYFLFVTKRGMIKRTLAPLYRNVRA--SGI---KAVLLREDD
ELIMVR-I---EHNDEVVLCTQGGTAIRFSV--VRPMRASGVKGIALR---DVVGAVVVPPWGHILTVSELGYGKRTPVGQYRLQSRGGRGVINM--TTG
Q-VRGAILVQDDDQLVMMTSANKVIRIGVKDISVVGRATQGVRLASLD--G-GTLAGFDLVR--------------------------------------
------------
>tr|F3AER5|F3AER5_9FIRM DNA gyrase subunit A OS=Lachnospiraceae bacterium 6_1_63FAA GN=gyrA PE=3 SV=1
-------HHYLMFFTSAGRVYRIKAYEIPEASRTARGTAIINLLQPEKITAVIPINKGNYLFMATKNGLVKKTPIEDYEN-RK--TGL---AAIALREDD
ELIEVK-T---DN-KDIILVTKFGQCIRFNE--VRSTRSMGVRGINLL---EVIGMQLTCQGDYLLIVSEKGLGKRTSISEFTRQNRGGKGVKCYKITTG
N-VIGVKAVNE-NEIMMITTEGIIIRLECEGISILGRITSGVKLMDLKD-D-ITVASIAKVR--------------------------------------
------------
>tr|R5RPD1|R5RPD1_9FIRM DNA gyrase subunit A OS=Firmicutes bacterium CAG:646 GN=gyrA PE=3 SV=1
-------HHYLMFFTNMGKVYRLKAYEIPEAGRTARGTAIINLLQPEKISAVIPINDDQYLFMATKKGLVKKTPILDYAN-RK--TGL---AAISLRDDD
ELIEVK-A---DS-KDIILVTKYGQCIRFDV--VRSTRSMGVRGINLG---GVIGMQLNTQGDYLLIVSENGMGKRTPMGEFTSQNRGGKGVKCYKITTG
N-VVGVKAVNE-NEIMMITTEGIIIRISCSDISILGRITSGVKLMNLDEN--VSVASIAKVR--------------------------------------
------------
>tr|U7D827|U7D827_9BACT DNA gyrase subunit A OS=Chitinivibrio alkaliphilus ACht1 GN=gyrA PE=3 SV=1
-------HSNLLFFTNFGRCYSIKVYAIPETGRQSKGRPLVNII-PEKIAACIPVKEEHYIVQTTQKGTINKQSLGAYAKIRR--TGI---NSVNMDEDD
RLVSVS-C---TNDAYIVIATLQGKAIRVSA--VRPLRTRGVRGISLR---DVIGTVTLTSEQEILTVTENGFGKRTALSEYRVTNRGGVGIINI--SNG
S-VVSVMAPDPEGDILIITRKGIIIRTEVAHISTTGRNTLGVKLINLAE-D-DAVIDVTSCT--------------------------------------
------------
>tr|A0A023DBV5|A0A023DBV5_9BACI DNA gyrase subunit A OS=Geobacillus caldoxylosilyticus NBRC 107762 GN=gyrA PE=3 SV=1
-------HNTILFFTNKGKVYRAKGYEIPEYSRTAKGLPLINLLEKEWINTIIPIHDNLYLFFTTKQGIAKRCPLSAFAH-RN--NGL---IAIHLREGD
ELISVK-T---DG-KHIIVGTKNGMLIRFPE--VRTMRATGVKAITLD--DDVVGMEILEDDCDVLVVTKNGYGKRTPASEYRLQSRGGKGIKTCNVTNG
P-VVAVKTVND-EDLMLITTSGILIRIAVSDISRVGRNTQGVKLIRLSEEH-EYVATVAKVP--------------------------------------
------------
>tr|M5JCJ6|M5JCJ6_9BACI DNA gyrase subunit A OS=Anoxybacillus flavithermus TNO-09.006 GN=gyrA PE=3 SV=1
-------HDIVLFFTNKGKVYKAKGYEIPEFSRTAKGIPIVNLLNKEVINTVIAIEEDAFLFFTTKQGTAKRSPLSSFAN-RN--HGL---IAIHLHEGD
ELISVK-T---DG-KHIIVGTKNGMLIRFPE--VRSMRAAGVKAITLC--GDVVGMESLNGDEEILIVTRNGYGKRTPASEYRVQSRGGKGIKTCNITNG
D-VVAVKTVTE-EDLMLMTASGVMIRIAVSDISVMGRNTQGVKLIRLDGEQ-EYVATVAKVP--------------------------------------
------------
>tr|A0A0Q3WU80|A0A0Q3WU80_9BACI DNA gyrase subunit A OS=Bacillus shackletonii GN=AN964_20335 PE=4 SV=1
-------HDTILFFTNKGKVYRAKGYEIPEYSRTAKGLPIINLLGKEWINTIIRVEEDSYLFFTTKKGISKRTPLSDFAN-RT--NGL---IAIHLREED
ELISVK-T---DG-KDIIIGTKNGMLIRFPE--VRSMRATGVKGITLS--EDVVGMEILDENNEVLIVTLNGYGKRTPASEYRIQSRGGKGIKTCNITNG
S-LVSVKTVTE-EDLMLITAGGVLIRMAVSDISLLGRNTQGVKLIKLGE-D-EYVATVAKVE--------------------------------------
------------
>tr|M4YUS6|M4YUS6_9EURY DNA gyrase subunit A OS=Thermoplasmatales archaeon BRNA1 GN=gyrA PE=3 SV=1
-------HDYLMFVTNTGRILWLKGYNIPEGSRQAKGKPVVNLLPEEIVTNVIPTAEDKCLVFCTRNGLIKKTQLSAYGNVRN--KGI---KAIRLDDDD
ELVEVW-S---KEGDEIVLASTDGQAIRFPE--VSATRTRGVRGMTVG---EVISMTVVKPEDMLLTVTENGFGKISIVSDYRLTHRGGKGVITI--TNG
G-VMSVRKVGPEDELMAISSSGKVIRMRVSDIRQTGRNAAGVKIMDLKD-G-ETIVSVNPVV--------------------------------------
------------
>tr|A0A0Q4BBV9|A0A0Q4BBV9_9EURY DNA gyrase subunit A OS=Methanomassiliicoccales archaeon RumEn M2 GN=AOA81_02360 PE=4 SV=1
-------HDYVMFVTDHGRLHWLKGYRIPEGGRHSKGKPIVNMIAEENVVSTICASDDRFLVFCTKEGIIKKTVLSAFKNVRR--KGI---KAIKLREDD
TLVETH-T---DGDDEIIIATHNGLAVRFHE--VGSKRTMGVKGVTLN---DVVSMSVVKPGDMLLTVSENGYGKISSVDDYRKINRGGKGVITL--TNG
G-VIAVRKVLESDELVVVSTQGKVIRIKVNEIRVTGRNAAGVRIMDLRN-G-DKVTALQPVA--------------------------------------
------------
>tr|M9SDN4|M9SDN4_9EURY DNA gyrase subunit A OS=Candidatus Methanomethylophilus alvus Mx1201 GN=gyrA PE=3 SV=1
-------HDYLMFVTNTGRILWLKGYNIPEGSRQAKGKPIVNLLNEETITTVIPTPDDKYLVFCTKNGVLKKTQLSQYGNVRS--KGI---KAIKLDDDD
ELVEAA-T---DGTDEIVLATNDGQACRFSE--VRPMRTRGVKGMTLG---NVVSMAVVKSDDLLLTVTEKGMGKTSVVRDYTIHHRGSKGVKTI--TSG
Y-VVSVRKVNDGDELMLVSNSGKIIRIQVNSIRQTGRAAQGVKVMELKD-D-DRVAAVEPVN--------------------------------------
------------
>tr|V8TQ46|V8TQ46_9CHLA DNA gyrase subunit A OS=Chlamydia pecorum DBDeUG GN=gyrA PE=3 SV=1
-------KDYLLIFTNFGQCYWIKVWRLPEGERRSKGKSLINFLEPEQVAAILNVK-D-FLFLATKQGVVKKVPLDAFSNPRK--KGI---RALEIDDND
ELIAACIE---NEHDRVMLFTKLGMAVRFPH--VRPMRARGVRGVSLKQ--CVVSCQIVTDNQSVLVVCENGFGKRSLVSDFRETNRGGIGVRSI--NNG
D-VLGAVPVADNDSILLMSGQGQAIRISMQDVRIMGRSTQGVRLVHLKD-G-DVLVAMERLP--------------------------------------
------------
>tr|A0A0D6DX35|A0A0D6DX35_9LACT DNA gyrase subunit A OS=Lactococcus piscium MKFS47 GN=gyrA PE=3 SV=1
-------HDHLLFFTNKGRVYRMKAYEIPEYGRQAKGLPIVNLLKDETIQTVINVEQERFLLFTTLRGIVKRTNANHFAN-RT--SGL---IALNLREDD
ELVNVL-T---TG-EELIIGTHNGYSVRFKE--LRDMRATGVKGVNLR---GVVGSSTINDSQEVLVVSENGLGKRTSAEHYPTKGRGGKGIKVMNVTTG
K-LAGLVTVNS-EDLMLITDTGVVIRTNVDNISQTGRSAQGVKVMRLDED--AKLVTFALVA--------------------------------------
------------
>tr|E3CJA6|E3CJA6_STRDO DNA gyrase subunit A OS=Streptococcus downei F0415 GN=gyrA PE=3 SV=1
-------HDVVLFFTNQGRVYRLKGYEIPEYGRTAKGLPVVNLLKTETIQTIISLN-EKSLFFTTRQGLVKRTSISEFTN-RQ--NGL---RALNLKDGD
ELINVL-T---TG-DEIIIGTHFGYSVRFKE--VRNMRATGVKGITLR---AVVGASVIRDDQEVLVITEKGYGKRTLASEYPTKGRGGKGIKTANITNG
S-LAGLVTVDH-EDIMIMTDTGVIIRTGVSNISQTGRSTMGVKVMRLDEN--AKIVTFALIE--------------------------------------
------------
>tr|T0URF7|T0URF7_9STRE DNA gyrase subunit A OS=Streptococcus sp. HSISB1 GN=gyrA PE=3 SV=1
-------HDHVYFMTNKGRVYRLKGYEIPEYGRTAKGLPIVNLLKDETVQTIISEK-ENYLFFVTRQGVVKRTKESEFSN-RQ--NGL---KALNLKEGD
ELINVI-T---NG-DDIIIGTKTGYSVRFNE--VRSMRATGVRGVNLR---GVVGASRITDDQEVLVITEKGYGKRTLASEYPTKGRGGKGIKTANITNG
K-LAGLVTVND-EDIMVITDTGVMIRTNVADISQTGRATLGVKIMRLDED--AKIMTLALVQ--------------------------------------
------------
>tr|M0BGN1|M0BGN1_9EURY DNA gyrase subunit A OS=Haloterrigena thermotolerans DSM 11522 GN=gyrA PE=3 SV=1
-------HDYLLCFTNQGEVYRLKTYEIPEMGRTARGKSAVNIL-PEDITAIVDTD-DEYVTMTTRNGYVKRTAGEAFDNIRS--TGI---IAADLETGD
ELVDVE-T---DGSQDLVIATEGGMTIRFDE--VRAMRARGVNGIKLQ---DVAGLVATDEEQALLTVTENGYGKRTPLSEYSTQSRYGKGLIDI--GNG
P-VTAVKAVSDDDQLVLMSERGQIVRTRVDEISTVSRNTMGVTVMDVEE-G-DAVAAVDDIP--------------------------------------
------------
>tr|F8D8D4|F8D8D4_HALXS DNA gyrase subunit A OS=Halopiger xanaduensis (strain DSM 18323 / JCM 14033 / SH-6) GN=gyrA PE=3 SV=1
-------HDYLLCFTNQGKVYQLKTYEIPEMGRTARGKSAVNIL-DEDITAIVDTD-DECVTMVTRNGYVKRTDGEEFDNIRS--TGI---IASDLEEGD
ELVDVE-T---DGTKDLVIATEGGMTIRFDE--VRAMRARGVNGIKLQ---DVAGLVATDEDKALLTVTRNGYGKRTRLSEYSRQSRYGKGLIDI--GNG
P-VTAVKAVDDDDQLVLMSEDGQIVRTRVDEVSTVGRNTMGVIVMEVEG-D-DAVASVDVVP--------------------------------------
------------
>tr|A0A099BAB9|A0A099BAB9_9HELI DNA gyrase subunit A OS=Helicobacter sanguini GN=gyrA PE=3 SV=1
-------HDTIMFITNRGQLYWLKVYRIPETGRTAIGKAVVNLINEEKIMTTITTHDDKSLVFFTKNGIVKRTNLSEYKNVRN--NGV---RAINLDEND
ELISAS-------VSELFIATREGQCIRFK---IRDIRARGVIGIKFKK--DVVSASAIKGNDKLLTISELGIGKQTTAAEYRITNRGGVGVIAMKLTTG
K-LITILSND-NMDLMVLTTSGKMIRTPLESIRETGRNASGVKIINLESSS-SKVAFASVCN--------------------------------------
------------
>tr|A0A0R1QCS3|A0A0R1QCS3_9LACO Dna gyrase subunit a OS=Lactobacillus nagelii DSM 13675 GN=FD45_GL002229 PE=4 SV=1
-------HDELLFFTNLGKVYRMKGYEIPEYSRMAKGIPVINLLGDEKVQTIINVSHQSYLFFTTKQGTVKRTVVDEFSN-RK--NGL---KAITLKDDD
ELISVL-T---ND-RNLIIGTHQGYAVSFSE--VRPMRASGVRGIRLR---NVVGAAILSADSKVFIVSEKGYGKQTSAAEYPIKGRGGKGIKTANVTNG
P-LIGLTTVQD-EDIMLITDKGVMIRFNIQSVSTTGRATLGVHLIKVADE--TSVATMAKVA--------------------------------------
------------
>tr|A0A0R1UUE9|A0A0R1UUE9_9LACO DNA gyrase subunit A OS=Lactobacillus satsumensis DSM 16230 = JCM 12392 GN=FD50_GL002066 PE=4 SV=1
-------HDELLFFTNMGKVYRMKGYEIPEYGRTAKGIPVINLLGAEKIQAVINISQEYYLFFTTKKGITKRTAVAEFAN-RS--NGL---KAVSLKDND
ELINVL-T---DG-QNIIIGTHLGYAVSFKE--VRSMRATGVRGIRLR---AVIGVDVLYPDSHVFVVSENGYGKQTPAKDYPIKGRGGKGIKTSNVTNG
P-LTGLTTVKD-EDIMLITNKGVMIRFNIQTVSVTGRATLGVHLIRVDDE--ALVSTMAKVV--------------------------------------
------------
>tr|A0A0R2C3W5|A0A0R2C3W5_9LACO Dna gyrase subunit a OS=Lactobacillus vini DSM 20605 GN=FD21_GL001618 PE=4 SV=1
-------HDELLFFTNLGKVYRMKGYEIPEYSRTAKGIPIINLLGEEKVQTVINVSKKCFLFFTTKYGVVKRTLVTEFSN-RK--NGL---KAITLKDDD
ELISVL-T---ND-RKLIIGTHLGYAVSFAE--VRAMRASGVRGIRLR---NVVGAAILDPESNVFIISEKGYGKQTPAIEYPIKGRGGKGIKTANITNG
P-LVGLTTVKD-EDIMLITDKGVMIRFNIQSVSTTGRATLGVHLIKVAAD--ASVATMAKVA--------------------------------------
------------
>tr|A0A084HA37|A0A084HA37_9BACI DNA gyrase subunit A OS=Bacillus sp. SJS GN=gyrA PE=3 SV=1
-------HDTILYFTNKGKVYRTKGYEVPEYGRTAKGLPIVNLLGREWVKAIIPVSDDWYLFFTTKEGISKRTPLSQFAN-RT--NGL---IALGLREED
ELISVR-T---DG-KDIIIGTKDGMMIRFPE--VRQMRATGVKGINLS--GDVVGMEILEEDTDILIVTRNGFGKRTPAGEYRIQSRGGKGLKTCNITNG
S-VVSFKASTE-EDLMLITANGVLIRMDVNDISTMGRNTQGVRLIRLGE-N-HHVATVALVE--------------------------------------
------------
>tr|A0A0M2P9K6|A0A0M2P9K6_9BACI DNA gyrase subunit A OS=Bacillus sp. SA1-12 GN=gyrA PE=3 SV=1
-------HDTILFFTNKGKVYRAKGYEIPEFSRTAKGLPIINLLSKEWVNAIIPVSDDWFLFFTTKEGISKRSPLSQFAN-RN--NGL---IAVSLREAD
ELISVK-T---DG-KDIIIGTKNGMLIRFPE--VRSMRATGVKGISLD--DDVVGMEILDEGVDVLIVTRNGYGKRTPSEEYRIQSRGGKGLKTCNITNG
H-VVSVKAATE-EDIMLITASGVIIRMDVATISSMGRNTQGVKLIKLDE-N-VAVSTVALVE--------------------------------------
------------
>tr|R5N858|R5N858_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:793 GN=gyrA PE=3 SV=1
-------HDIILFFSNKGKLYKLRGFEVPE-GRTAKGTAIVNLLSGEKITAVIPIK-NQFLLMGTKNGLIKKTPLKEYDSGKK--TGL---MSINLKEDD
ELIDVRLT---EGENNIVMVTRKGLCITFN---VRPIRSQGVLGIRID---SVIGMETINAKGTLLAITENGFGKRTELDEYRVQARGGRGVVTYKITTG
E-IVGIRITG-DDDILMITDTGTVIRIKASEISV-GRNTQGITLMRTS-DG-GKVVSIEKVN--------------------------------------
------------
>tr|W0K2C9|W0K2C9_9EURY DNA gyrase subunit A OS=Halobacterium sp. DL1 GN=gyrA PE=3 SV=1
-------HDYLLCFTNQGQVYRLKVYQVPEMSRTARGTSAVNIL-DEEISAVVTADDDEYLTMATRHGYVKRTSVGEFGNILT--TGI---IATSLEDGD
ELADVE-T---SGDDDVILGSEQGMAIRFDE--VRPMRARGVHGMNLE---DVAGVAAVDAERTLLTVTEFGYGKRTKLSEYRKQSRNGKGLVDI--DNG
D-VVSLDSVDDDDNLVAMSERGQIIRLPVDEISTYGRNTKGVKVMDVEE-G-DEVAAVSVYR--------------------------------------
------------
>tr|U2YGR6|U2YGR6_9EURY DNA gyrase subunit A OS=Halarchaeum acidiphilum MH1-52-1 GN=gyrA PE=3 SV=1
-------HDDLLCFTNQGQVYRLKVYQVPEMSRTARGTSAVNVVDDEEISAVVTADDDEYLTMATRDGYVKRTAVSEFANIRS--TGI---RAVRLEHGD
ELVDVEVT---DGEGDVIIGTEEGMAIRFDE--ARPMRARGVRGVKLD---QVAGVAAAGPERDLMTVTEYGYGKRTSLSEYRRQSRNGKGLVDI--GNG
R-VASVHSVAAGDEFVAMSEDGQIMRASVSEVSAYGRNTQGVTVMDLAE-H-DRLAAVDVFT--------------------------------------
------------
>tr|Q9HR29|Q9HR29_HALSA DNA gyrase subunit A OS=Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) GN=gyrA PE=3 SV=1
-------HDYLLCFTDQGQVYRLKVYQVPEMSRTARGTSAVNILDDEEISAVVT--DDEYLTMATRNGYVKRTSVGEFGNILS--TGI---IAIDLEDGD
ALADVE-T---DGSHDVILGSEAGMAIRFDE--VRAMRARGVRGMDLD---DIAGVAAVESDRSLLTVTEFGYGKRTRVGEYRSQSRNGKGLVDI--GNG
D-VVSVDAVGDDDSLVVMSADGQIIQMPVDEISTVGRNTKGVNIMAVGS-G-DEVAGVSVRA--------------------------------------
------------
>tr|S7J3V1|S7J3V1_CHLPS DNA gyrase subunit A OS=Chlamydia psittaci 10_1398_11 GN=gyrA PE=3 SV=1
-------KDYLLIFTNFGQCYWLKVWQLPEGERRAKGKPVINFLEPEQLAAVLNVK-G-FLFLATKKGIVKKVPLTAFSNPRK--KGI---RALEIDNGD
ELIAACIT---SDQERVMLFTKLGMAVRFVH--VRPMRARGVRGVSLKE--CVVSCQIVTEDQSVLVVCDKGFGKRSQVEDFRETNRGGVGVRSI--NNG
D-VLGAVPVVDHDSILLMSAQGQAIRINMQDVRIMGRSTQGVRLVHLKD-S-DVLVAMEKLS--------------------------------------
------------
>tr|A0A0R1U812|A0A0R1U812_9LACO DNA topoisomerase (ATP-hydrolyzing) subunit A OS=Lactobacillus kalixensis DSM 16043 GN=FC46_GL000840 PE=4 SV=1
-------HDMLLFFTNKGKIYSKKAYEIPEYGRTAKGLPIVNLLQDEKIQTVVNIPDDNYLFFITKMGIVKRTHVSEFQN-RN--SGL---IALTLRDGD
ELSNVL-T---DG-QNILIGTHLGYAVCFNE--VRPMRAAGVRGINLR---NVVGSEVIKPDDEVLVISEKGYGKRTPAKEYPVKGRGGKGVKTTNITNG
P-LAGVTVVDS-QDIMVITTDGIMIRFKINDVSQTGRNTLGVRLIRVDND--SKVSSLATVP--------------------------------------
------------
>tr|I7IYP5|I7IYP5_9LACO DNA gyrase subunit A OS=Lactobacillus pasteurii DSM 23907 = CRBIP 24.76 GN=gyrA PE=3 SV=1
-------HDMLLLFTNAGKVYSKKAYEIPEYGRTAKGLPIVNLLQDEKIQTVINIPDDNYLFFITKMGVVKRTHVSEFAN-RN--SGL---IALSLRDGD
ELSNVL-T---DG-QNILIGTHLGYAVTFSE--VRPMRATGVRGINLR---NVIGSDVIKPDDEVLVISEKGYGKRTSASEYPIKGRGGKGIKTANITNG
P-LAGITIVND-EDLMLITTDGIMIRFKAQNVSQTGRSTLGVRLIKVEED--SQVASLATVP--------------------------------------
------------
>tr|N2ARM9|N2ARM9_9LACO DNA gyrase subunit A OS=Lactobacillus sp. ASF360 GN=gyrA PE=3 SV=1
-------HDMLLFFTNKGKVYSKKAYEIPEYGRTAKGLPIINLLQEEKIQTVINIPDDNYLFFITKMGTVKRTHVSEFSN-RN--SGL---IALTLRDGD
ELSNVL-T---DG-QNILIGTHLGYAVTFNE--VRPMRAAGVRGINLR---HVVGSEVIKPNDDVLVISEKGYGKRTSASEYPIKGRGGKGIKTSNVTNG
P-LAGVTVIDT-NDIMVITTDGIMIRFKTDDVSQTGRSTMGVRLIKVSGD--NKVASLAIVP--------------------------------------
------------
>tr|A0A0F4M6N3|A0A0F4M6N3_9LACO DNA gyrase subunit A OS=Lactobacillus helsingborgensis GN=gyrA PE=3 SV=1
-------HDMLLFFTNKGKVYSKKAYEIPEFGRTAKGLPIVNLLQEEKIQTIVNIPDDQYLFFITKMGTVKRTHVSEFGN-RN--SGL---IALTLRDGD
ELNNVL-T---DG-QDILIGTHLGYAVRFNE--VRSMRAAGVRGINLR---NVVGSGVIKNSDEVLVISEKGYGKRTAAAEYPTKGRGGKGIKTANITNG
P-LSGVTVIDS-QDIMVITDDGIMIRFKTKDVSQTGRSTLGVRLIKVNDN--NKVASLAVVP--------------------------------------
------------
>tr|Q1JZE9|Q1JZE9_DESAC DNA gyrase subunit A OS=Desulfuromonas acetoxidans DSM 684 GN=gyrA PE=3 SV=1
-------HSYILVFTDQGKVYWLKVHEIPQGGRAARGKAIVNLLQPERVMTILPVK-DKYIIAATKNGVVKKTELMAYAN-RQ--GGI---ISMTIDEGD
SLVATR-T---DG-MDVLLASHHGKSIRFAE--VRPMRARGVRGMQLE--DTIIGMEVVNDSASLVSVTENGYGKRTNLSEYRVQSRSGKGIITIKTSNG
Y-VVDIKLVTE-EDLMFITDRGKILRTRVGSLSIIGRNTQGVRLMVLED-D-ERIVAVAKLA--------------------------------------
------------
>tr|D8P7F0|D8P7F0_9BACT DNA gyrase subunit A OS=Nitrospira defluvii GN=gyrA PE=3 SV=1
-------HDSLLFFTDAGKVYWLKVHEIPEASRAAKGKALVNLLAKEKVTATLPVK-DRFVIMGTKQGVIKKTELSAYSN-RQ--GGI---IALSLDAGD
KLIGVD-T---DG-REILLGTKQGITIRFKE--VRAMRAHGVRGITLE--DEVIGMETITPTTAILTVTEGGYGKRTPVNEYRVQGRGGKGIISVKTTNG
P-AVGFLQVRE-DEIMLMAAQGKVLRCKVDDIREIGRNTQGVRLLDMDGDE-DRVVAVVRLV--------------------------------------
------------
>tr|A0A0M4DEM5|A0A0M4DEM5_9DELT DNA gyrase subunit A OS=Desulfuromonas sp. WTL GN=gyrA PE=3 SV=1
-------HSYILVFTDLGKVYWLKVHEIPQGGRASRGKAIVNLLQTENVTTVLPVK-GKYIITATQNGTVKKTELMSYAN-RA--GGI---IALTIDEGD
RLISAR-T---DG-MDILLASRNGKSIRFPE--ARPMRARGVRGMMLE--NHLIGMEVVSESATLVTVTENGYGKRTNLDEYRVQSRGGKGIITIKTSNG
K-VVDIKLVDD-SDLMFITDRGKVLRTGVAALSIIGRNTQGVRLMVLEP-E-ERIVAVAKLA--------------------------------------
------------
>tr|Q54A16|Q54A16_CHLPN DNA gyrase subunit A OS=Chlamydia pneumoniae GN=gyrA PE=3 SV=1
-------KDYLLIFTNFGQCYWLKVWQLPEGERRAKGKPIINFLEPEELAAILNIK-G-FLFLATKRGVVKKVSLDAFSNPRK--KGI---RALEIDEGD
ELIAACIV---SDEEKVMLFTHLGMAVRFPH--VRPMRARGVRGVSLKE--KVVSCQIVTENQSVLIVCDQGFGKRSLVEDFRETNRGGVGVRSI--NNG
N-VLGAIPVTDHDSILLMSSQGQAIRINMQDVRVMGRSTQGVRLVHLKE-G-DALVSMEKLS--------------------------------------
------------
>tr|F8I312|F8I312_SULAT DNA gyrase subunit A OS=Sulfobacillus acidophilus (strain TPY) GN=gyrA PE=3 SV=1
-------HSYLCFFTNRGRIYRVKVHEIPEASRQAKGISVANLIAQERIAAVQTLT-DHYWVFATKRGVVKRTPLSDYET-RG--GGI---IAITLDDGD
ELIGVE-T---AG-SHIILATRHGQVIRFEE--VRPTRARGVTGIRLR--DMVVSLATVSE-PELLILTENGFGKRTRLDQFRVTGRGGQGIVGMRVTTG
Y-VVGIQPVES-EECMVISSEGTMIRLEVGSISEQGRATQGVKVMRLEDG--QHVSAFALVK--------------------------------------
------------
>tr|A0A095XQ05|A0A095XQ05_9FIRM DNA gyrase subunit A OS=Tissierellia bacterium S5-A11 GN=gyrA PE=3 SV=1
-------HNTLLFFTTAGRVYKLVANDIPKSTRTARGTHLVNCIPKEQVTEIYDISNYEYLLMVTRQGFVKKTLLSEYTNVRQ--SGL---IAINLRDGD
ELIKVVTT---TGDDHIIIGTKTGMAIVFS---VNPTRSLGVIGVRFK-G-EVVGADVLTSTDEVLTLSSDAYAKRNKATAYS-QQRGGQGARNFKKG-S
T-VVGLLTVK-NEEMLVITESGIVIRVPVDSISLKGKNTIGVKVQRLDE-T-DRIASVALAP--------------------------------------
------------
>tr|H1D1C1|H1D1C1_9FIRM DNA gyrase subunit A OS=Dialister succinatiphilus YIT 11850 GN=gyrA PE=3 SV=1
-------HNRILFFTNYGKVYMKTAIDLPKG-RTARGSALINYIPKERVTELLDIDDTKYLLMVTKKGYVKKTEIAEYRNINK--NGL---IAIRLNEGD
ELVTVLRV---KGDEDVILGTRFGMAIRFSI--VRSLRAAGVHGIRLSVG-EVVGAVIAA-DKDIFTISADGNAKRNKADAYR-QGRNGMGVRNFKKG-F
E-VVALVAAD-NDELVGVSEQGITIKTKASQITSKAKAGQGVILQRLEE-G-DRIASIDVLS--------------------------------------
------------
>tr|A0A062VBT7|A0A062VBT7_9EURY DNA gyrase subunit A OS=Candidatus Methanoperedens nitroreducens GN=gyrA PE=3 SV=1
-------HDYILFFTDRGKVYWLKVYEVPTAGRQARGTAIINLLQQEKINAYIPIS-EHYLLMVTKKGVVKKTVLSVFSN-RK--TGI---IAISLDDGD
KLVSVK-T---DG-RGIVIGTKHGKAIRFNE--VRDMRAYGVRGVKLV--DEVVSMAVVEE-ATLLTITEHGFGKRTGFEEYRIMNRGGQGVITIDVNNG
S-VVDIKTVRD-DEIMVTTSRGIIIRVPVSGIRIQGRNTQGVKIMNVDDK--DRVVGVATLA--------------------------------------
------------
>tr|D1YWG1|D1YWG1_METPS DNA gyrase subunit A OS=Methanocella paludicola (strain DSM 17711 / JCM 13418 / NBRC 101707 / SANAE) GN=gyrA PE=3 SV=1
-------HDHLLFFTNKGRVYVLKVYEIPEASRQSRGKAIVNLLTPESVNAMIPIK-KHYLIMCTREGTIKKTALSSFQN-RR--TGI---IAIGLDEGD
ELISVK-T---NG-QEVLIATRNGKANRFSE--VRPMRAGGVIGIRLT--DKVIGMEVVSE-ASILTVCENGFGKRTAISEYTPHHRGGQGMINIKTTNG
G-VVAIASVTD-DQLLVVTRDGIMMRINVKDISEISRNTQGVKIITLKSEN-DAVVGVAKLV--------------------------------------
------------
>tr|H8IA13|H8IA13_METCZ DNA gyrase subunit A OS=Methanocella conradii (strain DSM 24694 / JCM 17849 / CGMCC 1.5162 / HZ254) GN=gyrA PE=3 SV=1
-------HDNLLFFTNKGRVYSLKVYEIPVASRQSRGKAIVNLLTPESITAMIPIK-GHYLMMCTREGIVKKTPLSAFKN-RS--TGI---MAIKLDEGD
ELISVK-T---NG-QEVLIATRDGKANRFHE--VRSMRAAGVIGIRLA--DRVVGMEVLSE-ASILTVCENGFGKRTPVSEYTPHHRGGQGMINIKTTNG
G-VVAVASVTD-DQILLVTRDGIMMRIKVKDVSEIGRNTQGVKIITLKSED-DAVVAVAKLA--------------------------------------
------------
>tr|I7MR11|I7MR11_STRCB DNA gyrase subunit A OS=Streptococcus canis FSL Z3-227 GN=gyrA PE=3 SV=1
-------HDTLLFFTNFGRVYRLKAYEIPEYGRTAKGLPIVNLLKEETIQTIINAR-GKSFFFTTKQGVVKRTEVSEFNN-RQ--NGL---RALNLKEGD
QLINVL-T---DG-DDIIIGTQSGYSVRFNE--IRNMRATGVRGVKLR---EVVGASRIQDKQEVLVITENGYGKRTSATEYPTKGRGGKGIKTANITNG
Q-LAGLVTVDT-EDIMVITNKGVIIRTSVANISQTGRATLGVKVMKLDAD--AKIVTFALVE--------------------------------------
------------
>tr|A0A0P6SNY2|A0A0P6SNY2_9STRE DNA gyrase subunit A OS=Streptococcus phocae GN=AKK44_00535 PE=4 SV=1
-------HDTLLFFTNFGRVYRLKAYEIPEYGRTAKGLPIVNLLKDETIQTIINAR-DKFFFFTTKQGVVKRTSVTEFHN-RQ--NGL---RAITLKDGD
ELINVL-T---DG-EDIIIGTRLAYSVRFKE--IRHMRAAGVRGVRLR---GVVGASRIQDNQEVLIITENGYGKRTSAVEYPTKGRGGKGIKTANITNG
Q-LAGLMTVDT-EDIMVITDKGVIIRTNVTNISQTGRATLGVKVMRLDAD--SSIVTFALVE--------------------------------------
------------
>tr|A0A0G7SL21|A0A0G7SL21_9STRE DNA gyrase subunit A OS=Streptococcus equi subsp. equi GN=gyrA_2 PE=3 SV=1
-------HDTLLFFTNFGRVYRLKAYEIPEYGRAAKGLPVINLLKDETIQTIINAK-DKYFFFTTKQGIVKRTEVSEFSN-RQ--NGL---RALNLKEGD
ELINVL-T---NG-EDIIIGTRSGYSVRFNE--IRGMRATGVRGVKLR---EVVGASRINDKQEVLVITENGYGKRTSAAEYPTKGRGGKGIKTANITNG
Q-LAGLMTVDS-EDIMVITTKGVIIRTNVSSISQTGRSTLGVKVMRLDTD--SKIVTFTLVQ--------------------------------------
------------
>tr|R9M4X8|R9M4X8_9FIRM DNA gyrase subunit A OS=Oscillibacter sp. 1-3 GN=gyrA PE=3 SV=1
-------HDYILFFTDSGKVYRKKGYQIPE-GKTAKGTNIVNILQQERVQTMIHTRDGRFLFMVTRNGTVKRLPANTLKNLRN--NGL---RALRMDEGD
RLITVRET---DGEQKILIATHDGLAVCFD---VRPMRAMGVRGIRLR---YVVGAARA--GHEVLSITERGYGKRTPVEEYRITNRGGVGIKNYMITTG
A-VVGIKVVD-SEDLLLMTQTGILIRTHVESIRL-GRATQGVIVMRFKEEG-DRVISMALTE--------------------------------------
------------
>tr|R5DBP1|R5DBP1_9FIRM DNA topoisomerase (ATP-hydrolyzing) OS=Firmicutes bacterium CAG:83 GN=BN795_01459 PE=4 SV=1
-------HDYLLFFTDTGKVYRKKGYQIPEG-KTARGTNIVNILQQERIQTMLHYRGQLYLFMTTRNGTVKRLPVETLKNLRN--NGI---RALTLDEGD
ELINVQET---DGSQRILIATHDGQAVCFD---VRAMRAVGVRGIRLR---YVVGAARA--GKTVLSITERGYGKRTPVEEYRITSRGGLGIRNYMVTTG
P-IVGIKVVD-QEDLLLMTQAGILIRTAVDSIRI-GRATQGVIVMRFKEEG-DRVISMALAD--------------------------------------
------------
>tr|R6GRP8|R6GRP8_9FIRM DNA gyrase subunit A OS=Oscillibacter sp. CAG:241 GN=gyrA PE=3 SV=1
-------HDYILFFTDTGKVYKKKGYLIPE-GKAAKGTNIVNILQTERVQAMLHFRDQLYLFMTTRNGTVKRLEVSALKNLRN--NGI---RALTLDEGD
ELINVQET---HGSDRILIATHDGQAVCFD---VRAMRAVGVRGIRLR---YVVGAAKA--GKTVLSITERGYGKRTAVEEYRITARGGLGIRNYMVTTG
P-IVGIKVVD-TEDLLLVTEAGILIRTAVENIRI-GRATQGVIVMRFKEED-DRVISMALTD--------------------------------------
------------
>tr|R6TJ75|R6TJ75_9FIRM DNA gyrase subunit A OS=Oscillibacter sp. CAG:155 GN=gyrA PE=3 SV=1
-------HDYLFFFTDTGKVYRKKGYQIPQ-GKTAKGTNIVNILQQEKIQTMVHTRENRFLVMVTRNGTVKRLPVSTLKNIRA--SGI---RALRMEEGD
QLISVRET---DGTRKILVATHDGQAICFD---VRPMRAMGVRGIRLR---YVVGAARA--GKTVLSITEKGYGKRTPVEEYRITGRGGLGIRNYAVTTG
G-VVGIKVVD-SEDLLLVTKGGILIRTPVENIRV-GRSTQGVIVMRFKEEG-DQVISMALTD--------------------------------------
------------
>tr|S6ET79|S6ET79_LACLL DNA gyrase subunit A OS=Lactococcus lactis subsp. lactis A12 GN=LACR_1216 PE=3 SV=1
-------HDHLLFFTNLGRVYRMKGYEIPEYGRTAKGLPIVNLLKDEKIATIINVDAAKYLFFTTRNGIVKRTSTSQFSN-RT--NGL---KALKLRDGD
ELINVL-T---SG-DEVIIGTHLGYSVRFKG--VRDMRAAGVKGVNLR---GVVGTSRIDDSQEVLVISENGLGKRTQASEYPTKGRGGKGMKVMNVTTG
K-LAGLTAVND-EDLMVITDTGVIIRTNVANISQTGRAAQGVKVMRLDDE--AQIVTFALVD--------------------------------------
------------
>tr|A0A0M4H4D9|A0A0M4H4D9_9ENTR DNA gyrase subunit A OS=Buchnera aphidicola (Aphis glycines) GN=gyrA PE=3 SV=1
-------HDTILCFSSRGILYWMKVYHLPESSRHAKGRPIVNLLP-ERITAILPVHDNLNIFMATAQGVVKKSALKNFQKPRS--AGI---IAINLRAND
ELIGVALT---NGKNNVMLFTQNGKVVQFSENSVRTMRASGVRGIKIL--KSVVSLIIPSE-ESILIATNNGYGKRTKISDFPIKSRATQGVISIKITKG
K-IIGAIQVVETDQIMMITDAGTLVRIRVSEIGVLKRNTQGVILIRTS-KN-EKVVALQRIV--------------------------------------
------------
>tr|F7WZ57|F7WZ57_9ENTR DNA gyrase subunit A OS=Buchnera aphidicola (Cinara tujafilina) GN=gyrA PE=3 SV=1
-------HDTILCFSSRGILYWMKVYQLPEKSRHTRGRPIVNILP-ERITTILPITSSINIFMATAHGFVKKTSLNKFQKTKK--FWY---YAINLRKND
KLIGVSLT---NGHDTIMLFSSNGKIVHFSEKTIRNMRASGIKGMKIS--EKVVSLLVPNK-DNILIVTEHGYGKQTKINQFPIKSRATKGIISIKTTNG
I-VIGALQVKNDDQIMMITNAGKLVRTRISEIGILKRNTQGVILIRAS-KN-EKVVGLQKIK--------------------------------------
------------
>tr|Q057V6|Q057V6_BUCCC DNA gyrase subunit A OS=Buchnera aphidicola subsp. Cinara cedri (strain Cc) GN=gyrA PE=3 SV=1
-------HDTILCFSSRGLLYWMKVYQLPETSRNARGKPIVNLLP-ERITTILPISSSINIFMATALGFVKKTSLIQFKKPRN--SGI---IAINLRKND
KLIGVSLT---TGNNNICMFTSKGKVVQFSEKTIRKMRASGIRGMKIT--NNLVSLLVPNK-DDILIVTANGYGKRTNINQFPIKSRATKGVLSIRVTNG
V-VIGAIQVKQNDQIMIITNAGTLVRTRVSEIAILKRNTQGVILIRTI-KK-EKVVGLQKLS--------------------------------------
------------
>sp|P57277|GYRA_BUCAI DNA gyrase subunit A OS=Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) GN=gyrA PE=3 SV=1
-------HDTILCFSSRGILYWMKVYQLPESSRHARGRPIVNLLP-ERITAILPVHDNLNIFMTTAHGIVKKSSLSQFKKPRF--AGI---IAINLHAND
ELIGVALT---DGNNNIMLFTQNGKVVQFLENSVRTMRASGVKGIKIK--KNVVSLIVPKN-GSILIATKNGYGKRTKISDFPIKSRATQGVISIKITNG
K-IIGAIQVIEKDQIMMITDAGTLVRIRVSEVGVLKRNTQGVILIRTS-KN-EKVVALQKIV--------------------------------------
------------
>tr|A0A0F5HW02|A0A0F5HW02_9BACI DNA gyrase subunit A OS=Bacillus thermotolerans GN=gyrA PE=3 SV=1
-------HDTILFFTNKGKVYRLKGYQIPEFSRTAKGIPIVNLLDKEWVNTMIRIDQANYLFFATKSGIVKRTSLKEFTH-RT--NGI---RALTLREED
ELISVR-T---DG-KHIIVGTKQGMLIRFEE--VRQMRSMGVKGIRLD--GDVVGMELLAENDYVLVVTENGYGKRTPEEEYRIQSRGGKGLKTCNITNG
P-LVAVKTVTE-EDLMLITVGGVLIRMDVNDISITGRNTQGVKLIRLGD-E-ETVATVTKIE--------------------------------------
------------
>tr|A0A0C2XVD6|A0A0C2XVD6_BACBA DNA gyrase subunit A OS=Bacillus badius GN=gyrA PE=3 SV=1
-------HDTILFFTNKGKVYRLKGYQIPEFSRTAKGIPLINLLEKEWVNAMIRVEADAFLFFATKSGIVKRTQLKDFAN-RT--NGL---RALNLKEDD
ELISVR-T---DG-KHIVIGTRDGMMIRFEE--VRQMRSTGVKGIRLS--GDVVGMELLHENDYVLIVTENGYGKRTPEQDYRIQTRGGKGLKTCNITNG
P-LVAIKTVSE-EDLMLITVGGVLIRMDVNDISITGRNTQGVKLIRLHD-E-ETVATVTKIA--------------------------------------
------------
>tr|I8AKN5|I8AKN5_9BACI DNA gyrase subunit A OS=Bacillus macauensis ZFHKF-1 GN=gyrA PE=3 SV=1
-------HNTILFFTNKGKVYRLKGYEIPEMSRTAKGIPIVNMLQRETISAVIPVEDDWYLNFMTKHGITKRSPLSQFAN-RK--GGL---FAITLRDED
ELMGVK-T---NG-KDIIVGTNNGMAIRYRE--VRSMRAAGVKAITLG--NDVIGMEVLDETQEVLIVTDKGFGKRTPMEDYRLQSRGGKGIKTCNITNG
Q-IIALKTVTE-EDLMIITADGILIRMNIDGISSMGRNTQGVKLISMNE-G-NHVATVAVVE--------------------------------------
------------
>tr|I0XUD6|I0XUD6_9LEPT DNA gyrase subunit A OS=Leptospira licerasiae serovar Varillal str. VAR 010 GN=gyrA PE=3 SV=1
-------HDNVMFFSNIGKVYMMKAYELPQASKEARGKSLKAIIGEETVSAIFTFRKGKDLLLVTKNGFIKRVELSEFGNVKK--SGI---IAIGLRDGD
QLIQVS-V---EKGDNVMIFSANGLALRIE---IRAQRAQGVTGMRLSE--DIVGLSKVVEGDDIFLISENGYGKRLGFEEFGTKGRGGKGMAFLKVGNG
A-AVAVSSVG-EDEIILVTQQGMVIRTEANQISKMGRTAVGVRVVDIKD-N-DKVQDCTVIR--------------------------------------
------------
>tr|A0A068EX37|A0A068EX37_9LEPT DNA gyrase subunit A OS=Leptospira sp. GIMC2001:Bairam-Ali GN=gyrA PE=3 SV=1
-------HDNLMLFSNKGRAFNMKVYEIPIASKEARGKSLKAVINEEVITSLYQYRD-SALLMVTRQGFMKKILLNEFSNTKK--SGI---IALGLRDGD
TLIDVS-T---KSNEDVFIGTRNGLAIRMN---LRSQRAQGVTGMRLSD--DIAGVTIVKPDSSLFVLSEYGYGKRTSYDEFSTKGRGGKGMTYVKVGNG
K-SVGIATVS-NDEILVITQSGMAIRTPAKDVSIIGRTAVGVKVVDTKD-D-DGVIDFAVIS--------------------------------------
------------
>tr|T0C2H8|T0C2H8_9DELT DNA gyrase subunit A OS=Bacteriovorax sp. BAL6_X GN=gyrA PE=3 SV=1
-------HDKLLFFTSRGQVFSKKVYEIPEGTRTSKGRNIANLI-SDRVTEIICVPNEKYLIFATNKGLVKKTALEEYSNVKQ--SGL---IAIKLQDGD
HIVNVR-N---DGSKDILLCSSAGKIIRFDT--ARPMRSQGVKGININ---EIIGMELIDD-MEILSVTSQGYGKRTESSQYRKQTRGGKGILAM--TNG
E-IVQIKPVTDKDDLMIITDRGQVVRTKVSGVSLMGRATQGVRLIKPKE-G-EKVVSIAKII--------------------------------------
------------
>tr|T0RAR4|T0RAR4_9DELT DNA gyrase subunit A OS=Bacteriovorax sp. Seq25_V GN=gyrA PE=3 SV=1
-------HDTMYFFTSRGQVFSKKVYNVPEGTRTSKGRNIANLI-GDKINEIICVPSKLYLIFATKQGLVKRTSLEDYKNIKQ--SGL---IAIKLQDGD
SIANVR-S---DGTKDVLLCASTGKIIRFDE--ARPMRSQGVKGINID---EIVGMELIDD-VEILSVTENGYGKRTISSEYRKQTRGGKGILAM--TNG
D-IIQIKPVTDKDDLMIITNKGQVIRTKIAGISLMGRTTQGVRIINLKG-D-EKVVAVEKMM--------------------------------------
------------
>tr|T0T4J8|T0T4J8_9DELT DNA gyrase subunit A OS=Bacteriovorax sp. BSW11_IV GN=gyrA PE=3 SV=1
-------HSTILFFTNRGQVFSKKVYNVPEGSRTSKGRNIANLI-SETIKEIMCIPDGKFLIMASEKGLIKKTDLSEYKKIKQ--SGI---RAIKLQDGD
SICSVR-S---DGNKDVLLCSTSGKIIRFDE--ARPMRSQGVKGITLD---EIIGMELIDD-VEILSVTDNGYGKRTMSSQYRKQSRGGKGILAM--TTG
D-IIAIKPVTDKDDLMIITDKGQVIRTKISGISLMGRATQGVRLITVKD-Q-EKVVSVEKIV--------------------------------------
------------
>tr|E1X1M8|E1X1M8_HALMS DNA gyrase subunit A OS=Halobacteriovorax marinus (strain ATCC BAA-682 / DSM 15412 / SJ) GN=gyrA PE=3 SV=1
-------HSTILFFTNRGSVFSKKVYNIPEGTRTAKGRNIANLIPPDKIKEIMCIPEGKYLMFATEKGLVKKSALTDYNN-KQ--SGL---RAIKVQDGD
SVCSVR-S---DG-KDVLLCSTSGKIIRFDE--ARPMRSQGVKGINID--ERIIGMELID-SVEILSITENGYGKRTAASQYRKQTRGGKGILAMRLTNG
E-IKQIKPVSK-DDLMVITDKGQVVRTKISGISLMGRATQGVRIIKLKE-G-ESVVSVEKIV--------------------------------------
------------
>tr|A0A0D5NIZ6|A0A0D5NIZ6_9BACL DNA gyrase subunit A OS=Paenibacillus beijingensis GN=gyrA PE=3 SV=1
-------HHFLLFFTNKGKVYRLKAYEIPDLSRTARGTPIINLLQQETVNAVIPVEPDRYLFFGTRQGVVKKTPLDDYSN-RK--VGL---IAINLRDDD
DLISVK-T---DG-QEIIMGTAQGMSIRFPE--VRSMRATGVKGIQLD---DVIDMDVVAPDRDILIVTSKGYGKRTPESEYRIQSRGGKGIKTLNVTNG
T-IAGLKVVEG-EDLMIMTETGTMIRTSMEGISTMGRNTQGVKLINIRED--DAVATVTRVA--------------------------------------
------------
>tr|E0I977|E0I977_9BACL DNA gyrase subunit A OS=Paenibacillus curdlanolyticus YK9 GN=gyrA PE=3 SV=1
-------HHYLLFFTDKGKVYRLKAYEIPDLSRTARGTPIINLLQQEVVNAVIPVENDKYLFFATRQGVVKKTPLDDYAN-RK--VGL---IAISLREDD
DLISVK-T---DG-QEIIMGTSQGMSIRFPE--VRSMRATGVKGIQLD---EVIGMEIVHPENDVLIVTSKGYGKRTPVNEYRIQSRGGKGIKTLNVTNG
T-IVGLKVVED-EDLMIMTASGTMIRTSMDGISTMGRNTQGVKLINIRED--DAVSTVTRVA--------------------------------------
------------
>tr|L0EIX5|L0EIX5_THECK DNA gyrase subunit A OS=Thermobacillus composti (strain DSM 18247 / JCM 13945 / KWC4) GN=gyrA PE=3 SV=1
-------HHYLLFFTDKGKVFRLKAYEIPELGRTARGTPIINLIQPETINAVIPIEPDLYLFFATKQGIVKKTPLDDYSN-RK--VGL---IAINLREDD
ELISVK-T---DG-REIIMGTSQGMSIRFPE--VRPMRATGVKGIQLE---GVIDMDVVDPEQDVLIVTAKGYGKRTPASEYRTQSRGGKGIKTLNITNG
S-VVSLKMVAD-EDLMIMTSAGTLIRTSIAGISTMGRNTQGVKLINIRED--DAVATVTRVS--------------------------------------
------------
>tr|A0A0Q9KJB5|A0A0Q9KJB5_9BACL DNA gyrase subunit A OS=Paenibacillus sp. Soil522 GN=ASG81_19285 PE=4 SV=1
-------HHYLLFFTNKGKVYKLKAYEIPDLNRTARGTPIINLIQQETINAVIPVQSEHFLFFATRQGVVKKTPLDDYVN-RK--VGL---IAISLREDD
DLIGVK-T---DG-QEIIMGTAQGMSIRYSE--VRSMRATGVKGIQLD---DVIDMDVIVPDKDILIVTSKGYGKRTPVADYRIQNRGGKGIKTLNVTNG
P-IVSLKVVED-EDLMIMTASGTMIRTSMEGISTMGRNTQGVRLINTRED--DTVATVTRVA--------------------------------------
------------
>tr|C6CSZ5|C6CSZ5_PAESJ DNA gyrase subunit A OS=Paenibacillus sp. (strain JDR-2) GN=gyrA PE=3 SV=1
-------HHYLLFFTNKGKVYRLKAYEIPDLSRTARGTPIINLIQQETINAVIPVESESYLFFATRQGIVKKTPLDDYMN-RK--VGL---IAISIREDD
ELIGVK-T---DG-QEIVMGTAQGMSIRFSE--VRSMRATGVKGIQLD---DVIDMDVVNPENDVLIVTAKGYGKRTPMSEYRIQNRGGKGIKTLNVTNG
P-IVSLKVVLD-EDLMIMTALGTLIRTSMEGISTMGRNTQGVKLINTRDD--DTVSTVTRVA--------------------------------------
------------
>tr|I0B9T9|I0B9T9_9BACL DNA gyrase subunit A OS=Paenibacillus mucilaginosus K02 GN=gyrA PE=3 SV=1
-------HHYLLFFTNKGKVYRLKAYEIPDLSRTARGTPIINLIQQETINAVIPVESDKYLFFASKKGLVKKTSLDDYSN-RK--GGL---IAITLREDD
DLIGVR-T---DG-QSIIMGTAQGMSIHFPE--VRPMRATGVKGIQLD---EVIDMDVVHEDNSVLIVTSKGFGKRTPVSEYRLQSRGGKGIKTLNVTNG
P-VVGLKVVQE-EDLMIITAFGTVIRTSMSGISLMGRNTQGVRLINIREE--DEVSTLARVE--------------------------------------
------------
>tr|M0MFM4|M0MFM4_9EURY DNA gyrase subunit A OS=Halococcus saccharolyticus DSM 5350 GN=gyrA PE=3 SV=1
-------HDYLLSFTNQGYVYRLKVYEVPEMGRTARGKSAINLV-DEDITAVVATD-EECLTMVTREGYVKRTCATDFENIHS--NGL---IATRLEEGD
ELVDVE-T---DDDGDLLIATQQGMAIRFPK--AREMRARGVNGIKLT---DVAGLVAASDDTDLLTVTENGYGKRTPMGEYRTQSRYGKGLKDI--NNG
R-VCTVETATADDDLVVMSEGGQIMRTRVGDISTVGRNTMGVTVMDLDA-G-DHVACVDVLS--------------------------------------
------------
>tr|A2U0L8|A2U0L8_9FLAO DNA gyrase subunit A OS=Polaribacter sp. MED152 GN=gyrA PE=3 SV=1
-------HQYMMFFTQKGKVFWMRVYEIPEGGKNTKGRAMQNLINQDSVKAFLVTQNSHYVIMATKKGQVKKTSLEQYSR-RT--NGI---NAITIKEGD
ELLEAKLT---TGDSQVMLALASGKSIRFE---TRPMRASGVRGITLQE--DVIGMVAVNDESNILVVSEKGYGKRSSLE-YRITNRGGKGVKTLNISTG
N-LVAIKNVD-SNDLMIINKSGLVIRMAVEDLRVMGRATQGVRLINIKD-D-DSIAAVAKVV--------------------------------------
------------
>tr|I7LAM3|I7LAM3_9LACO DNA gyrase subunit A OS=Lactobacillus hominis DSM 23910 = CRBIP 24.179 GN=gyrA PE=3 SV=1
-------HDFLLFFTNLGKVYSKKAYEIPEFGRNAKGLPIINLLQDEKIQAVINVPQDNYLFFVTRLGTVKRTHVSEFSN-RR--SGL---IALTLRDGD
ELNNVL-T---NG-QNILIGTHLGYAVTFNE--VRAMRAAGVRGINLR---NVVGSDILEPDSEVLVISEKGYGKRTAASEYPVKGRGGKGIKTANIGNG
P-LAGVTVVND-EDIMLITSAGVMIRFDVNDVSQTGRATLGVKLIRVDDG--AKVASVTAIP--------------------------------------
------------
>tr|D6S3J7|D6S3J7_9LACO DNA gyrase subunit A OS=Lactobacillus jensenii JV-V16 GN=gyrA PE=3 SV=1
-------HDYLLFFTNKGKVYSKKAYEIPEYSRTAKGLPIINLLQDEKIQAMINVPEDGNLFFITKMGVVKRTSVEEFSN-RN--SGL---IALTLRDGD
ELSNVL-T---DG-QNIIIGTHMGYAASFKE--VRVMRAAGVRGINLR---NVVGSEVLKPGAEVLVISENGYGKRTAVSEYPIKGRGGKGILTTKLGNG
P-LAGMTVVDT-TDIMLITTDGIMIRFKTEDVSQTGRATMGVRLIKLGEG--DSVASLTAVP--------------------------------------
------------
>tr|A3CVD7|A3CVD7_METMJ DNA gyrase subunit A OS=Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1) GN=gyrA PE=3 SV=1
-------HDNLLCFTDRGRMYWLKIYDLPEGQRTGKGKALVNLLNGERVTTVIPVR-DHHLFFATRNGTVAKMALDEFSR-RQ--TGI---NAINLRDGD
ALVDVK-T---DG-QELILTTKFGQSLRFHE--VRPVRAMGVRGIKLR--DALQAIAIVE-DDHLLTITEQGYGKRTEFDEYRGHGRGTLGVRNIVVDAG
N-VVGSMAVSD-DEIIVMSASGIVIRTKVSEISIQKRGTRGVRVMKLDD-G-DRVIGFTILD--------------------------------------
------------
>tr|L0HHJ9|L0HHJ9_METFS DNA gyrase subunit A OS=Methanoregula formicica (strain DSM 22288 / NBRC 105244 / SMSP) GN=gyrA PE=3 SV=1
-------KDYLLCFTNNGRVYWLKVYQIPESSRIAKGKPIVNLLNDVVTT-VIPIRADQYLIFATKLGQTIKIQLDEFSNPRS--TGT---NAIRLKDND
RLVDVILT---GGNNELILTSRFGQSLRFHE--IRIVRAQGVRGMKLK---TIVAITLLEK-DHLLTISDVGFGKRSEFDEFRGHGRGTMGVRNM---DA
V-VIESRAVLDTDEIIAMTASGIVIRIPVSEFRIIGRGTKGVRVMKLDE-K-DKVVGIAVVS--------------------------------------
------------
>tr|H4GIG5|H4GIG5_9LACO DNA gyrase subunit A OS=Lactobacillus gastricus PS3 GN=gyrA PE=3 SV=1
-------HDSLLFFTNSGKVFAMKGYEIPEYGRSAQGIPIINLLGNEQISAVINVSDDRDLFFVTKEGTVKRTSVNEFKN-RS--NGL---KAINLHEGD
ELIHVE-I---DQ-QAMILGTRLGYSVSFKA--VREMRAAGVRGVRLR---GVIGAAQLSPDSNVLVISEQGYGKQTPATEYPIKGRGGKGIKTVNITNG
P-LVGLTTVQD-EDLMLATNKGVIIRFSVESVSVTGRSAIGVHLIKMNDD--SVVATMAKVD--------------------------------------
------------
>tr|A0A0R1UPS9|A0A0R1UPS9_9LACO DNA gyrase, A subunit OS=Lactobacillus equigenerosi DSM 18793 = JCM 14505 GN=FC21_GL001183 PE=4 SV=1
-------HDRLLFFTNSGKVFTMKGYEIPEYGRAAQGIPIINLLGNEQISAVINVSDDLDLFFATKQGTVKRTAVSEFNN-RS--NGL---KAINLHDGD
ELIHVD-I---RP-DNLILGTHLGYSVSFNA--IRQMRAAGVRGARLR---NLIGAAKLTPNSKVVVISERGYGKQTPASEYPIKGRGGKGIKTANITNG
P-LVGLTTVND-EDLMVVTNNGVIIRFGVENVSTTSRATIGVHLIKMNDD--SVVATMAKVA--------------------------------------
------------
>tr|C0WVU3|C0WVU3_LACFE DNA gyrase subunit A OS=Lactobacillus fermentum ATCC 14931 GN=gyrA PE=3 SV=1
-------HDLLLFFTNTGKVFAMKGYEIPEYGRAAQGIPIINLLDDEKVTAVINVALQKDLFFVTRQGTVKRTLVTEFKN-RS--NGI---KAINLHEGD
ELINVA-V---DD-QNMILGTHLGHAATFKV--VRSMRAAGVRGARLR---GLIGAAPLNEDDQVLVISEKGYGKKTPASEYPIKGRGGLGIKTVNVTNG
P-LAGLTTVQD-EDLMVVTDKGVIIRFGVESVSQTRRSAIGVHLIKMDAD--SVVATMTKVE--------------------------------------
------------
>tr|A0A072NJY8|A0A072NJY8_BACAZ DNA gyrase subunit A OS=Bacillus azotoformans MEV2011 GN=gyrA PE=3 SV=1
-------HNTILFFSNKGKVYRLKGYEIPEFSRTAKGIPIINLLEKEWINAVIPVEDDWYLFFATKQGVVKRSPLSSFAN-RK--GGL---IALHLREGD
EVISVG-T---DG-REIMIGTKNGMLIRFNE--VRSMRATGVKGINLN--DDVIGMEIIEGKEDVLVVTRHGYGKRTPLSEYRMQSRGGKGIKTCNITNG
P-LSAIKAVTE-EDLMLITESGIVIRMAVDTISITGRNTQGVKLMRLDE-N-EVVSTVAKVD--------------------------------------
------------
>tr|N4WQQ4|N4WQQ4_9BACI DNA gyrase subunit A OS=Gracilibacillus halophilus YIM-C55.5 GN=gyrA PE=3 SV=1
-------HDTVLFFSNKGKVYRAKGYEVPEFNRTAKGIPIINMLEQEWINAVISVQEDWNLVFTTKYGISKRTSLIQFAN-RK--GGL---IALNLREND
ELISVR-T---DG-KDMLIGTKYGYVIRFEE--IRTMRAAGVKGISLR--NDVVSMEIVEEGEYVLNVTDNGYGKRTPIEDYRITNRGGKGIVTCHITTG
E-VVAVKTVSE-EDIMIMTISGVLIRMQVEGISTTGRNTQGVRLIRLQE-G-EKVATVAKVD--------------------------------------
------------
>tr|K2GAT6|K2GAT6_9BACI DNA gyrase subunit A OS=Salimicrobium jeotgali GN=gyrA PE=3 SV=1
-------HSTVLFFSNKGKVYKLKGYEIPEFSRTAKGLPIINLLNNEWINDVIAVDEDWYFVFTTRHGVTKRTSLSKFAN-RK--GGL---IALSLREND
ELISVR-T---DG-KDIMIATRNGYLIRFPE--IRSMRAAGVKGISLR--DDVVSMELVEDDREILTVTDKGFGKRTPASEYRITNRGGKGILTCNLTNG
K-VVSTKAVTE-EDLMIMTASGVLIRMAAGSVSRTGRNTQGVRLIRLQE-G-EEVSTVARLE--------------------------------------
------------
>tr|C8PS29|C8PS29_9SPIO DNA gyrase subunit A OS=Treponema vincentii ATCC 35580 GN=gyrA PE=3 SV=1
-------HDYIMFITNEGKAYWVKVHEIPEASRTSRGSHIKSLLASEEITTIVSL-SDTYLLMATAGGIVKKVQTDSFQNAKT--RGI---IAIKLDEGD
KLVSAILT---TGKDELMLVTRQGQALRVSE--IRDQRSHGVIGIRLS---ELTGALRIN-NGKLLVMSENGYGKRVDFSEFSPHGRGTGGQKVY--TTG
E-VVGLLAVADDDEIVCITGQGKTIRVQVSSINVMGRAAQGVRILDIES-P-DQLIGLDVVA--------------------------------------
------------
>tr|A0A0A7X1T1|A0A0A7X1T1_TREPL DNA gyrase subunit A OS=Treponema pallidum subsp. endemicum str. Bosnia A GN=gyrA PE=3 SV=1
-------HDYVMFVTSRGRAYWLKVYGIPESGRANRGSHIKSLLMTEEITAIVSLRNKSYVFMATARGVVKKVTTDNFVNAKT--RGI---IALKLSGGD
TLVSAVLV---QDEDEVMLITRQGKALRMSG--VREMRSSGVIGIKLT---LVAGVLRV--QRKVLIMTENGYGKRVSFSEFSVHGRGTAGQKIY--TKG
A-IIGALAVLDTDECMCITGQGKTIRVDVCAISVLGRGAQGVRVLDIEP-S-DLVVGLSCVM--------------------------------------
------------
>tr|S3K2Y2|S3K2Y2_TREMA DNA gyrase subunit A OS=Treponema maltophilum ATCC 51939 GN=gyrA PE=3 SV=1
-------HDYIVFISTEGKAYWIKVHEIPEAGRASRGSHIKSLLAAEEIATVVSL-EEQHLFMATANGVIKKVKTADFKNAKT--RGI---IAINLDAGD
KIVSAILT---GGSDDLALASRRGKVLRITE--VRPMRSRGVSGLKLA---ELTAAVRVDTNANMLLVTESGYGKRVDFDQFSVHSRGTQGQIGY--NTG
E-VVGVIAVADTDEVMCITSQGKTLKLAASAISQQGRASQGVCILKIDS-P-DFVIGVDRVE--------------------------------------
------------
>tr|Q73QZ8|Q73QZ8_TREDE DNA gyrase subunit A OS=Treponema denticola (strain ATCC 35405 / CIP 103919 / DSM 14222) GN=gyrA PE=3 SV=1
-------HDYIMFITNAGKAYWLKVHEIQEASRTSRGSHIKSLLSSEEITAVVSL-DKTYLLMATAGGVVKKVTTDNFANAKT--RGI---IAIKLDEGD
KLVSAILT---GGKDEIMLITRRGQALRTSE--IRSQRSRGVTGIKLS---ELTGALRVTENQKMLVMTENGYGKRVEFSEFSAHGRGTGGQRIY--STG
E-VVGLLTVFDDDEVVCITGQGKTIRISVDSVGTMGRSAQGVRILDIES-P-DMLIGLDVVA--------------------------------------
------------
>tr|F4LP13|F4LP13_TREBD DNA gyrase subunit A OS=Treponema brennaborense (strain DSM 12168 / CIP 105900 / DD5/3) GN=gyrA PE=3 SV=1
-------HDYIMFITNEGKSYWLKVHEIPEAGRNSRGAHIKGLLTPEEITTVVSL-DEQYLFMATAAGVVKKVQTSQFSNAKT--RGI---IAIRLDEGD
KLVTAILS---GGTDELILISRRGQALRITE--VRPMRGRGVGGLKLA---ELAGALRVESDACMMLLTEKGFGKRVDFDEFAAHGRGTGGQRIY--STG
E-IVGTINAADSDEIVCITSQGKSLRVAANSVTKQGRSASGVRVFNIDP-P-DMVIGLDRVA--------------------------------------
------------
>tr|F2NXS7|F2NXS7_TRES6 DNA gyrase subunit A OS=Treponema succinifaciens (strain ATCC 33096 / DSM 2489 / 6091) GN=gyrA PE=3 SV=1
-------HDYLMFITTEGKAYWIKVHEIPEASKTSRGSHIKSLLAAEDITTIVSL-ENNYLFMATANGVVKKTPTSDFKNAKS--RGM---QAVRLDEGD
TLVSAILS---TGKDELLLVSRRGQALRINE--VRPMRSRGVAGLKLS---ELCSAIRIHTDSKILVVTEKGIGKRVDSAEFNAHGRGTGGQKIF--VKG
E-IIGALCVRDTDSIMCITSQGTSVRVEAKDITVQGRGASGIKVVSITD-P-DYVVGVDRIA--------------------------------------
------------
>tr|S3JLC3|S3JLC3_TRESO DNA gyrase subunit A OS=Treponema socranskii subsp. paredis ATCC 35535 GN=gyrA PE=3 SV=1
-------HDCIMFITNEGKAYWIKVHEIPEASKMSRGSHIKSLLAAEEITTTVTVKGDNYVLMATTNGVVKKTALSDFANAKT--KGV---IAIKLDGGD
KLVSAILT---AGKNDVFFVSRRGKALRISE--VRPMRSRGTRGMKLA---EIAAAVRA--GKSIMLVTEKGFGKRINPEDFKSHGRGTGGQRCY--TRG
E-IIGALAVADGDEVLCITSQGKTLRVAAGDIKEQGASSTGVSVVKVDA-P-DYLVGIDRVA--------------------------------------
------------
>tr|E7NQS3|E7NQS3_TREPH DNA gyrase subunit A OS=Treponema phagedenis F0421 GN=gyrA PE=3 SV=1
-------HDYIMFITNEGKAYWLKVHEIPEASRTSRGSHIKSLLSGEEITAVVSL-DSTYLLMATAAGVVKKVTTDNFQNAKT--RGI---IAIKLDDGD
KLVSAILT---TGKDEIMLITRHAQALRMTE--IRPLRSRGVAGIKLA---ELTGALRVADNQKMLIMTENGYGKRVEFSEFTPHGRATGGQRIY--STG
E-VVGLLTVLDDDEVVCITGQGKTIRVNVDSISIMGRSAQGVRVLDIES-P-DILIGLDVVA--------------------------------------
------------
>tr|A0A0K9GZI5|A0A0K9GZI5_9BACI DNA gyrase subunit A OS=Bacillus sp. FJAT-27997 GN=gyrA PE=3 SV=1
-------HDTLLFFTNKGKVYRAKGYEIPEYGRTAKGLPLINLLEKEWVNAIIPVKDGDYLFFTTKFGISKRSPLSSFAN-RN--NGL---IAVGLNEGD
ELISVR-T---DG-KQIVIGTKDGMLIRFPE--VRSMRAAGVKGISLR--DDVIGMEILEESEEVLIVTKFGYGKRTPAEEYRIQSRGGVGIKTCNVTNG
E-LVAVKTVT--EDIMIITAEGVLIRMAVGDISTTGRNTQGVKLIRLENTN-EFVATVAMAE--------------------------------------
------------
>tr|A0A0H4KQZ9|A0A0H4KQZ9_9BACI DNA gyrase subunit A OS=Bacillus endophyticus GN=gyrA PE=3 SV=1
-------HDTILFFTNKGKVYRTKGYEIPEYSRTAKGLPIINLLKKEWINAIIPVKDTDYLFFTTKDGIAKRTPLSSFEN-RT--NGL---IAINLREED
ELISVR-T---NG-QHMVIGTKKGLLIRFDE--VRSMRATGVKGITLA--DDVVGMEISADEDDILVVTKNGYGKRTPVEDYRIQTRGGKGLKTCNITNG
D-VVALKSVND-DDLMLITVHGVLIRVSVEDISQTGRNTQGVKLIRLGD-D-EYVSTVARVQ--------------------------------------
------------
>tr|E4TPA1|E4TPA1_MARTH DNA gyrase subunit A OS=Marivirga tractuosa (strain ATCC 23168 / DSM 4126 / NBRC 15989 / NCIMB 1408 / VKM B-1430 / H-43) GN=gyr
-------HNYLLIFTELGKVYWIKVYRLPEGSKTSKGRAIQNLINSDSVRAVINVENNNFLVMCTEKGTIKKTTLEAYSR-RA--NGI---NAISINEGD
RLLNVKLT---NGDNNIIIAARSGRAIRFH---VRPMRAAGVRGITLKG--DVVEMVAITRNANLLVVSEKGYGKRSDIEDYRITKRGGKGVKTLNVTTG
E-LVAIKEVI-SDDLMIINKSGITIRMAVESLRVMGRATQGVRLIKVNE-N-DSISSVEKVE--------------------------------------
------------
>tr|L8K1L2|L8K1L2_9BACT DNA gyrase subunit A OS=Fulvivirga imtechensis AK7 GN=gyrA PE=3 SV=1
-------HNYLLIFTAFGKVFWKKVYGIPEGSKTSKGRAIQNLINPDKVRAVINVEDNNFVMMCTENGTIKKTSLKAYSR-RQ--NGI---NAITVRDGD
RLLDVKLT---NGDNHIVIAKRNGKAIHFH---VRPMRASGVRGVTLEA--DVVGMVCISRESNLLVVSEKGYGKRSLVEDYRITKRGGKGVKTINVTTG
K-LVAIKEVV-SDDLMIINRSGITIRLAVSGLRVMGRATQGVKLIRLNE-N-DEISSVEKIE--------------------------------------
------------
>tr|R6PNA7|R6PNA7_9CLOT DNA gyrase subunit A OS=Clostridium nexile CAG:348 GN=gyrA PE=3 SV=1
-------HHYIMFFTNTGRVYRLKGYEIPEASRTARGTAIINLLQPEKITAMIPIDEGQYLFMATKKGLVKKTPITDYAN-RK--TGL---AAITLREED
ELIEVK-T---DQ-QDIILVTKYGQCIRFNE--VRATRSMGVRGMNLA---RVVGMQLHTQGTHLLIVSEKGMGKRTAMEEFTSQNRGGKGVKCYKITTG
N-VVGVKAVND-NEIMIINTEGIVIRMECNSISVLGRITSGVKLINLNDN--ATVASIAKVR--------------------------------------
------------
>tr|C6LKK8|C6LKK8_9FIRM DNA gyrase subunit A OS=Marvinbryantia formatexigens DSM 14469 GN=gyrA PE=3 SV=1
-------HEYLMFFTNLGKVYRLKAYEIPEAGRTARGTAIINLLQPEKITAVIPIREDHYLFMATKKGLVKKTPITDYAN-RK--TGL---AAISLREDD
ELIEVK-T---DN-KDILLVTAYGQCIRFHE--VRSTRSMGVIGINLM---GVVGMQLDCQGEYMLIVSEKGMGKLTAMEEFKVQNRGGKGVKCYKILTG
N-VIAAKAVND-SDIMIINTEGIIIQMPCSDISVLNRITSGVKLMNLEK-D-VQVASITKVR--------------------------------------
------------
>tr|A0A0K9NEH3|A0A0K9NEH3_9FIRM DNA gyrase subunit A OS=Dorea sp. D27 GN=gyrA PE=3 SV=1
-------HHYIMFFTNTGRVYRLKAYEIPEASRTSRGTAIINLLQPEKITAVIPIEEGEYLFMCTKKGLVKKTPITDYAN-RK--TGL---AAITLREED
ELIEVK-T---NN-RDIILVTKYGQCIRFNE--VRSTRSMGVRGMNLA---RVIGMQLDSQGTHLLIVSEKGMGKRTGMEEFTSQNRGGKGVKCYKITTG
N-VVGVKAVDD-DEIMIINTGGIIIRMKCDNISSLGRVTSGVRLINLPDG--DTVASIAKVR--------------------------------------
------------
>tr|F3APG7|F3APG7_9FIRM DNA gyrase subunit A OS=Lachnospiraceae bacterium 9_1_43BFAA GN=gyrA PE=3 SV=1
-------HNYIMFFTNTGRVYRMKGYEIPEAGRTARGTAIINLLQPEKITAMIPIRDGKYLFMATKKGLVKKTPITDYAN-RK--TGL---AAITLREDD
ELIEVK-T---DN-KDIIMVTKYGQCIRFKE--VRSTRSMGVRGMNLS---RVIGMQLHTQGDYLLIASEKGMGKRTAIEEFTCQNRGGKGVKCYKITTG
N-VIGVKAVND-NEIMIINTEGIVIRMECAGISILGRVASGVKLINLDSN--TKVASIAKVR--------------------------------------
------------
>tr|M5R6B6|M5R6B6_9BACI DNA gyrase subunit A OS=Bacillus stratosphericus LAMA 585 GN=gyrA PE=3 SV=1
-------HDTILFFSNKGKVYRAKGYEIPEFGRTAKGIPIINLLEKEWINAIIPVSEDSYLFFTTRHGVSKRTSLSQFAN-RN--NGL---IALSLRDED
ELMAVR-T---NG-KQIIIGTKKGMLIRFDE--VREMRAAGVKGITLS--DDVVGMEILEPDANVLIVTEKGYGKLTPEKEYRVQSRGGKGLKTCKITNG
P-LVAVKATNEEEDLMIITGSGVIIRMAVSDISTTGRVTQGVRLIRLGDD--EHVATVALVE--------------------------------------
------------
>tr|R5L751|R5L751_9SPIR DNA gyrase subunit A OS=Brachyspira sp. CAG:700 GN=gyrA PE=3 SV=1
-------KDYLFIFTDRGKAFWLKVHEIPALTKLSQGKSIKFILNPEKITSYFTVSSKQSIIMVTKKGTIKKMELKHLENAKK--RGI---LALTLENND
ELVAVSAV---QTGDDFIMTTDSGLALRINE--VRNMRAGGVKGITLS---ICVSGNGI--GESLIVITENGIGKRLSSKQFNVKGRGGHGQIYI--DTG
R-VVSVKTVGDKDEIMVVTTDDMTIKIKANSIPELGRNAKGVKIVNISE-G-ARVSDLAVVP--------------------------------------
------------
>tr|R6RVA7|R6RVA7_9FIRM DNA gyrase subunit A OS=Anaerostipes sp. CAG:276 GN=gyrA PE=3 SV=1
-------HHYIMFFTNMGRVYRMKAYEIPESSRTARGTAIVNLIQPEKITAVIPINEDHYLFMATKSGVVKKSPIMEYAN-RK--TGL---LAITLKEND
ELIEVK-T---DN-QDVFLVTKNGQCIRFHE--VRSIRAMGVRGINLD---DVIGMQLNSQGEALLFVSENGMGKRTAMTEFTPQHRGGKGIRCYKITTG
D-VVGVKAVDE-NEVMMITTEGVVIRMGVDGISMLGRNTSGVKLMNLDD-N-VIVASLAKVR--------------------------------------
------------
>tr|V2XZI3|V2XZI3_9FIRM DNA gyrase subunit A OS=Catonella morbi ATCC 51271 GN=gyrA PE=3 SV=1
-------HHYILFFTNKGRVYRLKAYQIPEASRTARGTAMVNLLQPEQVKAVINIRTDGYLFMATKRGIVKKTALSEYAN-RK--TGL---QAINLREDD
DLIEVK-T---NN-NDIFLVTKNGMCIRFNE--VRPTRSMGVIGMTID---TIVAMQLDTQGAKLLIVSENGLGKRTEISEFTTQHRGGKGVKCYKIVTG
L-VIGAKSVNN-NEIMLITKAGIIIRMAVESISTLGRITSGVKLMNVDG-D-NVIAKIAKVR--------------------------------------
------------
>tr|A5Z7E9|A5Z7E9_9FIRM DNA gyrase subunit A OS=Eubacterium ventriosum ATCC 27560 GN=gyrA PE=3 SV=1
-------HDYILFLTNTGRIYKLKCYEIPEAGRTARGMAIVNLLQPEKISAMVQMKEDKYLIMATKKGTIKKTPIMAYTN-RK--SGI---QAITLREDD
ELIDVT-S---DN-DNIMLITKKGQGIKFRE--VRETRAMGVRGIELN---DVISMQLESQGECVLIVSANGMGKRTPFTDFKLQNRGGKGVKCYKISTG
E-VVGAKAVNG-NEIMMITNEGIVIRMFVDDISILGRVTLGVKLMNTGDKD-IVVASITKVK--------------------------------------
------------
>tr|A0A0R1P6I4|A0A0R1P6I4_9LACO DNA topoisomerase (ATP-hydrolyzing) OS=Lactobacillus frumenti DSM 13145 GN=FD27_GL000578 PE=4 SV=1
-------HDLMLFFTNSGKVYSMKGYEIPEYGRSAQGIPIINLLGDEKINAVINVSDDKYLFFVTKQGTVKRTPVSEFQN-RS--NGL---KAINLHDND
ELIHVA-I---KD-QNMIIGTHNGYALSFDS--VRSMRAAGVRGIRLR---NVIGAAPLNDDSNVLVISELGYGKQTPASEYPIKGRGGMGVKTVNVTNG
P-LAGLTTVQD-EDIMLVTDKGVIIRFGIESVSQTGRSALGVHLIKMDKG--TTVATIAKVA--------------------------------------
------------
>tr|A0A0R1UEA8|A0A0R1UEA8_9LACO DNA gyrase, A subunit OS=Lactobacillus ingluviei DSM 15946 GN=FC43_GL000707 PE=4 SV=1
-------HDELLFFTNTGKVFAMKGYEVPEYGRSAQGIPVINLLGDEKISAVINVQHDQDLFFATKLGVVKRTAVSEFAN-RS--NGL---KAINLHDHD
ELIAVD-I---DH-QNMILGTHLGYAVSFPA--VRAMRAAGVRGARLR---GLIGAAPLNADSQVLVLSENGYGKQTPAAEYPIKGRGTMGIKTVNVTNG
P-LVGLTTVDD-EDIMLVTDKGVIIRFGAETVSTTGRSAMGVRLIKMAAD--SKVATMATVA--------------------------------------
------------
>tr|A0A0R1NZ20|A0A0R1NZ20_9LACO DNA gyrase, A subunit OS=Lactobacillus mucosae DSM 13345 GN=FC47_GL000384 PE=4 SV=1
-------HDILLFFTNSGKVFSMKGYEVPEYGRSAQGIPIINLLGDEKITAVINVSTDKFLFFVTKQGTVKKTPVDDFRN-RS--NGL---KAIQLHDGD
ELIHVN-I---DG-QNMILGTRLGYAVSFNA--VRSMRAAGVRGAKLR---GVIGAAPLDSDSNVFVISENGFGKQTPAAEYPIKGRGGKGIKTVNVTNG
P-LAGLTTVKD-EDIMLVTDKGVIIRFGIETVSQTGRAAVGVHLIRMDDD--SKVATMAKVA--------------------------------------
------------
>tr|C7XXJ6|C7XXJ6_9LACO DNA gyrase subunit A OS=Lactobacillus coleohominis 101-4-CHN GN=gyrA PE=3 SV=1
-------HDMLLFFTNSGKVFSMKGYEIPEYGRSAQGIPIINLLGDEKINAVINVSADRDLFFVTKQGVVKRTAVEEFKN-RS--NGL---KAINLHDGD
ELIAVE-I---DH-QNMIIGTHEGYAVSFSA--VRSMRAAGVRGVRLR---GVIGAGQLNPDSRVLVISEKGFGKQTPAAEYPIKGRGGKGIKTVNVTNG
P-LAGLTTVDD-EDIMLVTTEGVIIRFGVETVSETGRATIGVHLIKLTDG--SKVATMTRVA--------------------------------------
------------
>tr|A0A0R2I0A1|A0A0R2I0A1_9LACO DNA gyrase, A subunit OS=Lactobacillus secaliphilus GN=IV45_GL001019 PE=4 SV=1
-------HDMLLFFTNSGKVFSMKGYEIPEYGRSAQGIPVINLLSDEKISAVINVSEDKDLFFATKQGIVKRTPVAEFQN-RS--NGL---KAINLHEND
ELIAVE-I---DH-QNLILGTHQGYSVSFNS--VRSMRAAGVRGARLR---NLIGAGKLNPDDNVLVISANGYGKQTPAAEYPIKGRGGKGIKTVNVTNG
P-LVGLTTVKD-EDIMLVTTKGVIIRFGVETVSTTGRSTIGVHLIKLTDG--AQVATMAKVA--------------------------------------
------------
>tr|F0IFE1|F0IFE1_9FLAO DNA gyrase subunit A OS=Capnocytophaga sp. oral taxon 338 str. F0234 GN=gyrA PE=3 SV=1
-------HQYMLFFTEKGKCFWLRVYEIPEGGRNTKGRAIQNLINSDNVKAFICTQNSHYVIMATKKGIIKKTALEQYSR-RQ--NGI---VAITIKEDD
ELLEARLT---TGSSQVMMAVKSGKAIRFP---VRSVRGSGVRGISFDEK-DVIGMITIEN--TVLVVSENGYGKRTFIDVYRITNRGGKGVKTISITTG
K-LVAIKSVS-EDDLMIINKSGMAIRMSVEALRVMGRATQGVRLINIKE-N-DSIAAVAKVM--------------------------------------
------------
>tr|M3EU93|M3EU93_LEPIR DNA gyrase subunit A OS=Leptospira interrogans serovar Lora str. TE 1992 GN=gyrA PE=3 SV=1
-------HDNIMFFSNIGKVYVMKAYELPIASKEARGKSLKAIINEEYISSVFTFRMDKDLLLVTRKGFIKRIQLKEFGNVKK--SGI---IAIGLREGD
ELIKVS-M---TDKDEVMIFSKKGLALRIE---IRAQRASGVTGMRLAD--DIVGLSKYKEGEDIFVVSEEGYGKRLGFEEFAAKGRGGKGMAYLKITNG
F-SVGTGSVG-EDEIILITQQGMTIRINAFDISKLGRTAVGVRIVDLKD-N-DKVQDFTVLG--------------------------------------
------------
>tr|G2Z868|G2Z868_LISIP DNA gyrase subunit A OS=Listeria ivanovii (strain ATCC BAA-678 / PAM 55) GN=gyrA PE=3 SV=1
-------HDTLLFFTNTGKVYRSKGYEVPEYGRTAKGIPIINLLGSEQVNAVINLSDDSYLFFTTKHGVVKRTTLSQFAK-RQ--SGL---RAVELREND
ELISVQ-T---DG-KNMIIATKHGQSIYFPE--IRVMRAAGVRGIRLR--DDVIGMEVLEDDEKVLVVTEKGYGKQTPASQYPLRNRGGMGVKTVTITNG
N-LVAMKTVTE-EDLMLMTVSGVLIRFEIDTVSQTGRSAMGVKLIRLDE-D-EKVATVAKVP--------------------------------------
------------
>tr|B3QRZ3|B3QRZ3_CHLT3 DNA gyrase subunit A OS=Chloroherpeton thalassium (strain ATCC 35110 / GB-78) GN=gyrA PE=3 SV=1
-------HHYILFFTSHGKCYWLKVHEIPEAGRTARGRSITNLIETEKIKASINVK-TQFIVMATKNGTIKKTPLSEYSN-RR--SGI---IAINITDND
ELVGAS-T---DG-HQIVLAKNTGYAVRFPE--VRPMRSIGVKGASIS--EAIISMV-STPDATLLAITDNGYGKRSAIEDYRMTKRGANGVITLKANVG
K-LVDMLEVNG-EDIIIITNKGIVNRQHIADIRVMGRNTSGVRLIRLDE-D-DFVSAVARVP--------------------------------------
------------
>tr|I7A2W9|I7A2W9_MELRP DNA gyrase subunit A OS=Melioribacter roseus (strain JCM 17771 / P3M-2) GN=gyrA PE=3 SV=1
-------HHYIMFFTDKGKCYWLKVHEIPEGGRTAKGRSILNLIEKEKIAAFVAVK-DKYVVMVTEKGTIKKTVLSAYSN-RR--GGI---NAINLADGD
NLVEAK-S---DG-NDIIIGTRNGMAIRFNE--VRDMRATGVRGINLA--DKVIGMIVVRNS-TLLVVTNKGYGKRSELDDYRLTRRGGKGIITIKTSNG
K-MIAMKEVNT-DELVIITTKGMVIRQAVKDIRIMGRNTQGVRLIKLNEG--DEIADIARVA--------------------------------------
------------
>tr|Q3B6P3|Q3B6P3_CHLL7 DNA gyrase subunit A OS=Chlorobium luteolum (strain DSM 273 / 2530) GN=gyrA PE=3 SV=1
-------HNYILFFTNTGRCYWLKVYEIPEAGRAARGRALANIMEPEKIKAYINIR-PGYIIMATADGIVKKTALEEFSR-RR--NGI---AAITIDEGD
ALLDAR-T---DG-HQVILAKSSGLVVRFPE--VRPMRAMGVKGITLD--EKCIAMV-TTKDTALLAVTDNGFGKRSRVEDYRLTKRGARGVITLKAHIG
S-LVGLLDVND-DDLILITTHGIVNRQHVSDIRITGRNTSGVKLIRLMA-G-DTISALARVP--------------------------------------
------------
>tr|A0A081SFH7|A0A081SFH7_9CHLB DNA gyrase subunit A OS=Chlorobium sp. GBChlB GN=gyrA PE=3 SV=1
-------HHYILFFTTFGKCYWLKVHEIPEAGRAARGRSLNNLMESEKIRAYINVK-SLYVVMATKNGMIKKTALSEYSN-RK--TGI---IAVNIEKGD
ELIEAK-T---DG-HQIVLAKNSGYAVRFME--VRPMRATGVKGAEVE--EEVVSMV-TTRDITLLTITDSGYGKRSDLEEYRMTKRGAAGVITLKANVG
N-LVAMIEVAT-DDLILITKNGIVNRQHVSDIRVMGRNTSGVRLIRLQE-G-DAVSAVARVP--------------------------------------
------------
>tr|B3QRK9|B3QRK9_CHLP8 DNA gyrase subunit A OS=Chlorobaculum parvum (strain NCIB 8327) GN=gyrA PE=3 SV=1
-------HNYILFFTTAGRCYWLKVYEIPEAGRSARGRSLANIMEPEKIRTYINIR-PHFIIMATANGIVKKTDLKQYSN-RR--TGI---NAITIEEGD
ELIEAR-T---DG-HQVILAKSSGYAVRFPE--VRSMRAMGVKGITLD--ERCISMV-TTKDTSLLAVTDNGYGKRSKVEDYRMTKRGARGVITIKAHIG
N-LVGLLDVNE-DDLIIITTNGIVIRQHVSDIRVLGRNTSGVRLIRLDA-G-DRISATARVP--------------------------------------
------------
>tr|B4S3A3|B4S3A3_PROA2 DNA gyrase subunit A OS=Prosthecochloris aestuarii (strain DSM 271 / SK 413) GN=gyrA PE=3 SV=1
-------HNYILFFTSMGRCHWLKVYEIPEAGRTARGRSLANIMEKETIRAYINVK-PLFIVMATARGLIKKTEIEAFSR-RR--NGI---AAISIEDGD
ELIEAR-T---DG-HDIIMAKNSGYAVRFAE--VRAMRAMGVKGITLD--EYCISMV-TSKDTSLLAVTDNGFGKRSLVDDYRLTRRGARGVITLKAHVG
N-LVGLLDVNG-DDLIIITANGIVNRQHVSNIRLTGRNTSGVRLIRLMQ-G-DKISATARVP--------------------------------------
------------
>tr|B4SAT3|B4SAT3_PELPB DNA gyrase subunit A OS=Pelodictyon phaeoclathratiforme (strain DSM 5477 / BU-1) GN=gyrA PE=3 SV=1
-------HNYILFFTNRGRCHWLKVYEIPEAGRAARGRALANIMEQEKIRAYINIR-PGFIVMATTNGIVKKTPLEDFSH-RK--NGI---AAITIDEHD
ELLDAR-T---DG-HQIILAKNSGFVVRFPE--IRSMRAMGVKGITLD--EKCISMV-TTKDTALLAVTDNGFGKRSRVEDYRLTRRGARGVITLKAHVG
A-LIGLLDVND-DDLIIITAQGIVNRQHVSDIRLTGRNTSGVRLVRLMA-G-DIISALARVP--------------------------------------
------------
>tr|A1BJS0|A1BJS0_CHLPD DNA gyrase subunit A OS=Chlorobium phaeobacteroides (strain DSM 266) GN=gyrA PE=3 SV=1
-------HNYILFFTTRGRCYWLKVYEIPEAGRTARGRSLANIMEPEKIRAYINIR-PGFIVMATGNGTVKKTGLDEFSR-RR--NGI---AAITIEEND
ELIDAR-T---DG-HQIILAKSSGYVVRFPE--IRSMRAMGVRGITLD--EKCISMV-TTKDTTLLAVTDNGFGKRSRVEDYRLTKRGARGVITLKAHTG
A-MVGLLDVNE-DDLIIITNNGIVNRQHVSDIRLTGRNTSGVRLIRLMA-G-DIISALARVP--------------------------------------
------------
>tr|B3EE75|B3EE75_CHLL2 DNA gyrase subunit A OS=Chlorobium limicola (strain DSM 245 / NBRC 103803) GN=gyrA PE=3 SV=1
-------HNYILFFTNTGRCYWLKVYEIPEAGRAARGRSLANIMEPEQIKAYINIR-PGYIVMATTNGIVKKTPLDDFSN-RR--TGI---AAITIEEGD
ELLDAR-T---DG-HQIILAKSSAYAVRFPE--IRSMRAMGVKGITLD--EKCISMV-TTKDTALLAVTDNGFGKRSRVEDYRLTRRGARGVITLKAHIG
A-LVGLIDVND-DDLIIITTNGIVNRQHVSDVRMTGRNTSGVRLIRLMA-G-DKISALARVP--------------------------------------
------------
>tr|Q3ANY5|Q3ANY5_CHLCH DNA gyrase subunit A OS=Chlorobium chlorochromatii (strain CaD3) GN=gyrA PE=3 SV=1
-------HNYILFFTTSGRCYWLKVYEIPEAGRAARGRSLANIMEPEKIRTYINIR-PGFIVMATTHGIVKKTALEEFSH-RR--TGI---AAITIDEGD
ELLDAR-T---DG-HQIILAKNSGFVVRFPE--VRPMRAMGVKGITLD--EKCIAMV-TTRDTALLAVTDNGFGKRSRVEDYRLTRRGARGVITLKPHIG
A-LVGLLDVNE-DDLILITVNGIVNRQHVSDIRITGRNTSGVRLIRLMQ-G-DSISALARVP--------------------------------------
------------
>tr|I0AFG3|I0AFG3_IGNAJ DNA gyrase subunit A OS=Ignavibacterium album (strain DSM 19864 / JCM 16511 / NBRC 101810 / Mat9-16) GN=gyrA PE=3 SV=1
-------HQYILFFTDRGRCYWLKVHEIPEGGRTARGRSIVNLLEKENITAFVAVK-DQYLIMVTEQGTVKKTVLSAYGN-RK--GGI---NAINLVPGD
KLIEVK-T---DG-NDIVIGTRNGFAIRFHE--VRDMRATGVRGIKLV--DKVVGLLVIRHQTSVLVVTEKGYGKRSDINDYRITKRGGKGVITVKTTVG
K-MIAMMEVVK-DELVIISTQGMVIRQSVKDIRVMGRNTQGVRVIRLNEG--DSIADIARVI--------------------------------------
------------
>tr|B3EK37|B3EK37_CHLPB DNA gyrase subunit A OS=Chlorobium phaeobacteroides (strain BS1) GN=gyrA PE=3 SV=1
-------HNYILFFTNKGRCHWLKVYEIPEAGRAARGRSLANIMEPEKIKAYINVK-PLFIIMATAKGSIKKTEIEAFSR-RR--NGI---AAITIEDGD
ELIDAR-T---DG-HDIILAKNTGYAVRFAE--VRPMRAMGVKGISLD--ETCISMV-TSKDTSLLAVTDNGFGKRSKVEDYRLTRRGAKGVITLKAHVG
H-LVGLLDVNS-DDLIIITSNGIVNRQHVSNIRLTGRNTSGVRIVRLMQ-G-DTISATARVP--------------------------------------
------------
>tr|A0A0A7LIE3|A0A0A7LIE3_9EURY DNA gyrase subunit A OS=Candidatus Methanoplasma termitum GN=gyrA PE=3 SV=1
-------HDYLMFITNHGRLHWLKGYRVPEGSRQSKGKPIINMISEEMVVSTICVHENEYLAFCTKNGLLKKTSLSAYKNVRA--RGI---KAIKFDEGD
ELIETS-T---EENDQIIIATKNGQAVRFNE--VRSTRTMGVKGVTLN---DVISMAVVRPEDKLLTVTENGYGKISDVADYRQTNRGAKGVITI--DNG
K-VVSVRKVSAGDQLMVTSMSGKMIRMSVDEIRETGRNAKGVRIMDMRD-G-DKVTAVQPII--------------------------------------
------------
>tr|C1A5L6|C1A5L6_GEMAT DNA gyrase subunit A OS=Gemmatimonas aurantiaca (strain T-27 / DSM 14586 / JCM 11422 / NBRC 100505) GN=gyrA PE=3 SV=1
-------HTYMLIFTDDGRCFWLKVHELPQAGRNTRGKPIVNLI-PTRIRAIVVTKDTEFLLFCTRNGTVKKTALSQYSNPRA--NGI---KAIKIEQDD
ELMDVQ-T---SGNNDVVLATRHGLSVRFHE--VREMRTTGVKGIELR---DLVGMVVIKR-ATLLVVTERGLGKCSEVSEYRVQKRGGKGILTL--TTG
D-VIALMEVVPEDELMLMTRQGIAIRSKVSEIRVTGRAAQGVKLVALDD-L-DGVSAVARVI--------------------------------------
------------
>tr|W0RKH2|W0RKH2_9BACT DNA gyrase subunit A OS=Gemmatirosa kalamazoonesis GN=gyrA PE=3 SV=1
-------HDYIMIFTDDGRCFWLKVHEIPQAGRATRGKPIVNLI-PTGIRSMVPVREDQYLLFCTKQGTVKKTCLSEYGNVRA--NGV---KAIKIERGD
ELIDVQ-T---SGTNDIVLATKHGLSIRFHE--VRDMRTTGVKGVELR---DVISMVVIKR-ATLLVVTEKGMGKVTDIDEYRVQKRGGKGIITV--TTG
N-VVSLMEVLPEDEIMLITKQGIIIRSAVNEVRNTGRNAQGVRLVNLDA-N-DIVCSVARVV--------------------------------------
------------
>tr|D6ZSC2|D6ZSC2_STRP0 DNA gyrase subunit A OS=Streptococcus pneumoniae serotype A19 (strain TCH8431) GN=gyrA PE=3 SV=1
-------HDHLLFFTNKGRVYRLKGYEIPEYGRTAKGLPVVNLLKDESIQTVINVE-DAYLFFTTRHGIVKRTSVKEFAN-RQ--NGL---KALNLKDED
ELINVL-A---EG-MDIIIGTKFGYAVRFNQ--VRGMRATGVKGVNLR---GVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAKITNG
L-LAGLMTVQD-EDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQD--AQIVTFTTVA--------------------------------------
------------
>tr|F5LHF6|F5LHF6_9BACL DNA gyrase subunit A OS=Paenibacillus sp. HGF7 GN=gyrA PE=3 SV=1
-------HHYLLFFTDRGKVYKLKAYEIPDLSRTARGTPIINLIQQETVSAVIPVQADNYLFFATKRGIVKKTPLDDYIN-RK--GGL---IAINLRDDD
SLIGVK-T---DG-RHIIMGTRDGMSIRFPE--VRSMRATGVKGIQIG---EVIDMDVVDEDASVLIVTSKGFGKRTPIAEYRVQSRGGKGIKTLNVTNG
A-VVGLKVVNE-EDLMIITASGTLIRTSISGISEMGRNTQGVRLINIRED--DEVATVTHVA--------------------------------------
------------
>tr|V9W1R1|V9W1R1_9BACL DNA gyrase subunit A OS=Paenibacillus larvae subsp. larvae DSM 25430 GN=gyrA PE=3 SV=1
-------HHYLMFFTDKGKVYRLKAYEIPELGRTARGTPIINLIQQETVNAVIPIESGHFLFFATQQGIVKKTPLKDYNN-RK--GGL---IAINLREDD
RLIGVK-T---DG-CNIIMGTRQGMSIHFPE--VRSMRATGVKGIHIS---DVIDMDIVDENNTVLIVTSKGFGKRTPMSEYRIQTRGGKGIKTLNVTNG
P-VVGLKVVED-EDLMIITASGTVIRTSMSGISIMGRNTQGVRLINTRED--DEVATVTRVE--------------------------------------
------------
>tr|A0A090QFC7|A0A090QFC7_9FLAO DNA gyrase subunit A OS=Nonlabens ulvanivorans GN=gyrA PE=3 SV=1
-------HQYMLFFTEKGKCFWMRVYEIPEGSRTSKGRAIQNLINPDTVKAVICTQNSHYVIMCTKKGVVKKTSLEQYSR-RT--NGI---NAITIREGD
TLLEAKLT---TGDSHVMLGLKSGKAIRFD---TRAMRASGVRGITLAD--DVIGMIAVNDESNILVVSEKGYGKRSSLD-YRETNRGGKGVKTISVTTG
G-LVALKNVT-EDGLMIINKSGVAIRIDVKNLRVMGRATQGVRLINLKG-N-DSIAAVAKVA--------------------------------------
------------
>tr|I6ZLD9|I6ZLD9_STRIN DNA gyrase subunit A OS=Streptococcus iniae GN=gyrA PE=3 SV=1
-------HDTLLFFTNLGRVYCLKAYEIPEYGRTAKGLPIVNLLKDETIQTIINAR-DKYFFFTTRQGIVKRTGASEFNN-RQ--NGL---RALNLKEGD
QLINVL-T---DG-EDIIIGTKSGYSVRLQE--IRNMRATGVRGVKLR---DVVGASTITDHQEVLIITENGYGKRTLASEYPTKGRGGKGIKTANITNG
E-LAGLTTVND-EDIMVITNKGVIIRTSLANVSQTGRATLGVKVMRLDKE--SKIVTFALVN--------------------------------------
------------
>tr|G5KBS8|G5KBS8_9STRE DNA gyrase subunit A OS=Streptococcus pseudoporcinus LQ 940-04 GN=gyrA PE=3 SV=1
-------HDTLLFFTNKGRVYRLKAYEIPEYGRTAKGLPIVNLLKDETIQTIINAR-NKFFFFTTRQGLVKRTNASEFGN-RQ--NGL---RALNLKDGD
ELINVL-T---DG-EDIIIGTKSGYSVRFEE--IRNMRATGVRGVKLR---GVIGASRISDSQEVLVITEKGYGKRTRATEYPTKGRGGKGIKTANITNG
Q-LAGLVTVTH-EDIMIITNKGVIIRTSIADVSQTGRSTMGVKVMRLDQD--SKIVTFALVD--------------------------------------
------------
>tr|B9DS54|B9DS54_STRU0 DNA gyrase subunit A OS=Streptococcus uberis (strain ATCC BAA-854 / 0140J) GN=gyrA PE=3 SV=1
-------HDTLLFFTNKGRVYRLKAYEVPEYGRTAKGLPVVNLLKDETIQTIIKAK-GKYFFFTTRQGLVKRTNASEFHN-RQ--NGL---RALNLKEGD
ELINVL-T---NG-EDIIIGTRLGYSVRFNE--IRQMRATGVRGVKLR---QVVGAARITDDQEVLIITENGYGKKTLASEYPTKGRGGKGIKTANITNG
P-IAGLVTVSQ-EDIMIITNKGVIIRTHISDVSQTGRATLGVKVMRLDQD--AKIVTFALVE--------------------------------------
------------
>tr|M3HNM9|M3HNM9_9STRE DNA gyrase subunit A OS=Streptococcus parauberis KRS-02083 GN=gyrA PE=3 SV=1
-------HDTLLFFTNKGRVYRLKAYEIPEYGRTAKGLPIVNLLKDETIQTIINAR-DKYFFFTTKGGVVKRTNASEFNN-RQ--NGL---RALNLKEDD
ELINVL-T---DG-EDIIIGTRSGYSVRFNE--IRNMRATGVRGVKLR---EVVGASRITDDQEVLIITENGYGKRTAASEYPTKGRGGKGIKTANITNG
P-LAGLTTVSD-EDMMIITNKGVIIRTSISNVSQTGRATLGVRVMRLDQN--SKIVTFALVE--------------------------------------
------------
>tr|W7D646|W7D646_9LIST DNA gyrase subunit A OS=Listeria rocourtiae FSL F6-920 GN=gyrA PE=3 SV=1
-------HDTLLFFTNTGKVYRAKGYEIPEYSRTAKGIPIINLLGSEKVNAVINLRDDQYLFFTTKLGVVKRSTLTQFAK-RQ--SGL---RAVELREND
ELISVQ-T---DG-KKIIIGTKFGQSIYFEE--IRVMRAAGVRGIRLR--EDVVGMEILEDDEKVLVVTENGYGKQTLASQYPLRNRGGMGVKTINITNG
N-LVALKTVTE-EDLMLMTIGGVLIRFSVGDISQTGRSAMGVKLIRLDE-D-EFVATVAKVP--------------------------------------
------------
>tr|R3U6X5|R3U6X5_9ENTE DNA gyrase subunit A OS=Enterococcus phoeniculicola ATCC BAA-412 GN=gyrA PE=3 SV=1
-------HDTLLFFTNNGKVYRAKGYEIPEYGRTAKGIPVINLLGDEKIQAIIAVEDGHYLFFTTRLGTVKRTTVTAFSN-RS--NGL---IAIGLKEND
ELVNVL-T---DG-ANIIIGTHAGYSVTFKE--VRDMRASGVRGIRLR---DVIGAATMDEDKEVLVITENGYGKRTKVSEYPVKGRGGKGIKTANITNG
P-LAGLTTVTE-EDVMLITDKGVIIRFSVGTVSQTGRSTLGVRLMKMEAE--AKVVTMAIVA--------------------------------------
------------
>tr|S0P307|S0P307_9ENTE DNA gyrase subunit A OS=Enterococcus saccharolyticus ATCC 43076 GN=gyrA PE=3 SV=1
-------HDTLLFFTNAGKVYRAKGYEIPEYGRAAKGIPVINLLGDERIQTIISVSEGNYLFFTTKLGVVKRTSVMAFSN-RS--NGL---IAIGLKEGD
ELVNVL-T---KG-DVMIIGTHKGYSVTFKE--VRDMRAAGVRGIRLR---DVVGAAVIREGDEVLVITENGYGKRTAGSEYPIKGRGGKGIKTANITNG
P-LAGLTTVTE-EDILLITNKGVIIRFSAETVSQTGRATLGVRLMKMEED--AKVVTMASVD--------------------------------------
------------
>tr|A0A0N0ISN2|A0A0N0ISN2_PEDAC DNA topoisomerase (ATP-hydrolyzing) (Fragment) OS=Pediococcus acidilactici GN=AN404_05350 PE=4 SV=1
-------HDVLLFFTNAGKVYRMKGYEIPEYSRTAKGIPVINLLGDESIQAVINIGEHRYLFFTTLQGVAKRTPVAEFMN-RS--NGL---KAINLKDGD
EVINVV-T---DG-QNIIIGTHNGYAISFKE--VRSMRATGVRGIRLR---NVVGSAVLAPESKVMVITEKGYGKQTPAEEYPIKGRGGKGIKTANITNG
P-LAGLVTVEN-EDVMLITDRGVMIRFNVDNVSTTGRSTLGVHVIKTDEN--SKVATMAIVE--------------------------------------
------------
>tr|G8PE84|G8PE84_PEDCP DNA gyrase subunit A OS=Pediococcus claussenii (strain ATCC BAA-344 / DSM 14800 / JCM 18046 / KCTC 3811 / P06) GN=gyrA PE=3 SV=
-------HDVLLFFTNAGKVYRMKGYEVPEYSRTAKGIPVINLLGSETVQAVINVGSKRCLFFTTLKGVVKRTAVSEFLN-RS--NGL---KAINLKDKD
ELINVA-T---TG-ENMIIGTHKGYAVSFKE--VRTMRATGVRGIRLR---EVVGVDVLRPDSNVLVITEKGYGKQTPASEYPIKGRGGKGIKTANITNG
P-IAGLATVKD-EDIMLITDRGVMIRFNINTVSQTGRATLGVHVIRIDDG--SKVATMAKVA--------------------------------------
------------
>tr|A0A0R2KXG8|A0A0R2KXG8_9LACO DNA gyrase subunit A OS=Pediococcus stilesii GN=IV81_GL001558 PE=4 SV=1
-------HDVLLFFTNAGKVYRMKGYEIPEYSRTAKGIPVINLLGSESIQAVINIGANRYLFFTTLNGVTKRTPVSEFLN-RS--NGL---KAISLKEND
EVINVV-T---DG-QNIIIGTHKGYAVSFKE--VRSMRATGVRGIRLR---EVVGSAILKPDSKVLVITENGYGKQTPASEYPIKGRGGKGIKTANITNG
P-LAGLVTVET-EDVMLITDRGVMIRFDVNNVSTTGRATLGVHVIKTDEN--SKVATMAIVD--------------------------------------
------------
>tr|A0A0R2NJU6|A0A0R2NJU6_9LACO GyrA protein OS=Pediococcus argentinicus GN=IV88_GL000937 PE=4 SV=1
-------HDVLLFFTNAGKVYSMKGYEIPEYSRTAKGIPVINLLGSEKIQAVINIGENRFLFFTTLKGVAKRTPVSEFLN-RS--NGL---KAINLKEED
ELINVA-T---SG-ENIIIGTHKGYAVSFSE--VRSMRATGVRGIRLR---EVVGVDILKPDSNVLIITENGYGKQTPAGEYPIKGRGGKGIKTANITNG
P-LAGLTTVSE-EDIMLITDRGVMIRFNIDSVSQTGRATLGVHVIRIDEG--SKVATMAKVA--------------------------------------
------------
>tr|U2JZ56|U2JZ56_9FIRM DNA gyrase subunit A OS=Peptostreptococcaceae bacterium oral taxon 113 str. W5053 GN=gyrA PE=3 SV=1
-------HDMILFFTNKGKVYSQFAYEIPE-SRTAKGQAIINLLHEEKVNAVFPVQ-ESCLTFATKKGMIKRTLVSEYENIRK--NGI---VAIKLVDDD
ELISVKMT---DEKDKAIFITQQGMGIAFP---VRIMRTQGVRGITLR---NVVSFEILE-DKDVLIVSEYGFGKRTSAEQYTIQNRGGKGVYTYKITTG
Y-VVAAKIVN-EDELIMISMQGEVIRLAVKQISE-GKRTSGVKLKDINRNE-DKIVAIARYV--------------------------------------
------------
>tr|B0SK36|B0SK36_LEPBP DNA gyrase subunit A OS=Leptospira biflexa serovar Patoc (strain Patoc 1 / ATCC 23582 / Paris) GN=gyrA1 PE=3 SV=1
-------HDNLMLFSNKGRAFLLKVYELPIATKEARGKSLKAVINDEIITSLFTFRE-SYLLMVTREGFVKKIQLDEFTNTKK--SGI---IAIGLRDGD
ELIDVA-N---PNNYDVFIGSKNGLAIRMN---LRSQRASGVTAMKLED--DIAGITKVEPNTNLFCISENGFGKRTDFEEFSTKGRGGKGMTYLKIGNG
R-AVGISSVK-EDELLVITQSGMAIRVEVKTISMVGRSAMGVKVVNTKD-E-DFVKDFAVVR--------------------------------------
------------
>tr|W7AQI8|W7AQI8_9LIST DNA gyrase subunit A OS=Listeria aquatica FSL S10-1188 GN=gyrA PE=3 SV=1
-------HDTLLFFTNTGKVYRAKGYEVPEYGRTAKGIPLINLLGSEQVNAVINLSDDDYLFFATKHGVVKRSALSQFAN-RQ--SGL---RAVDLREND
ELISVQ-T---DG-KKMIIATKAGQSIYFPE--IRVMRAAGVRGIRLH--DDVIGMEVLEDDQNVLVVTENGYGKQTPAEQYPLRNRGGMGVKTVSITNG
P-LVAMKTVSD-EDIMLMTIHGVLIRFEVETVSETGRSTMGVKLIRLDE-N-EKVATVAKVP--------------------------------------
------------
>tr|W7CXZ2|W7CXZ2_9LIST DNA gyrase subunit A OS=Brochothrix campestris FSL F6-1037 GN=gyrA PE=3 SV=1
-------HDTILFFTNTGKVYRAKGYEIPEFSRTAKGLPVVNLLGKEEINAMISIKQDHFLFFATRNGVVKRTQLSQFTN-RT--SGL---RAIDLREND
ELIRVQ-T---NG-NHVIMATHLGQSIHFQE--VRIMRAAGVRGIRLN--ADVVGMEVVKPADKVLIVTENGYGKQTPIEQYSVQGRGGKGVKTVSITNG
P-LTNMITVNE-EDLMIMTVEGVLIRMSVDAISETSRSTMGVRLIRLDE-K-DKVATIAPTE--------------------------------------
------------
>tr|D1JED8|D1JED8_9ARCH DNA gyrase subunit A OS=uncultured archaeon GN=gyrA PE=3 SV=1
-------RERLIFFTEFGKAYQVKTYEIPPSSRHSKGKPLVNIPGITEERAVAIPEEGAYLVFATKRGVVKRSSLAKLKAIRS--TGV---VAVRTTKGD
SLADVVLIKPGAGQNGIILSSKNGKAIFFHE--LREMRAAGVRGMRLE---EIASVEALDVKSRAVTITEKGYGKRTKLDAYRETHRGGKGVISI--GNG
K-VVCIKQVKNTDELMVATSDGMVTKISVRSISVQGRNTQGVRIMNVKK-G-ERVVAVDILS--------------------------------------
------------
>tr|R6WRN1|R6WRN1_9FIRM DNA gyrase subunit A OS=Dorea sp. CAG:317 GN=gyrA PE=3 SV=1
-------HHYIMFFTNTGRVYRLKGYEIPEASRTSRGTAIINLLQPEKISAVIPIDDGEYLFMATKKGLVKKTPIKEYAN-RK--TGL---AAITLREED
ELIEVK-T---NN-QDILMVTKYGQCIRFSE--VRSTRSMGVRGMNLS---RVIGMQLDSQGSELLIVSEKGMGKRTDMIEFTRQNRGGKGVKCYKITTG
N-VVGVKAVND-DEIMIINTEGIIIRMKCEGISVLGRITSGVKLINLKEG--DIVASIAKVR--------------------------------------
------------
>tr|R9MHF8|R9MHF8_9FIRM DNA gyrase subunit A OS=Lachnospiraceae bacterium 3-2 GN=gyrA PE=3 SV=1
-------HHYIMFFTNTGRVYRMKAYEIPEASRTSRGTAIVNLLQPEKISAVIELDDGEYLFMATKRGLVKKTPIKEYEN-RK--KGL---AAITLREDD
ELIEVK-T---DG-NDIFLVTKYGQCIRFNE--VRPTRSMGVRGMNLS---RIIGMQLEIQGKELLIASEKGMGKRTDTSEFTCQNRGGKGVKCYKITTG
N-VVGVKAVND-DEIMIINTEGIIIRMKCEGISVLGRVTSGVKLINLNDG--DTVASIAKVR--------------------------------------
------------
>tr|R7FV83|R7FV83_9FIRM DNA gyrase subunit A OS=Dorea longicatena CAG:42 GN=gyrA PE=3 SV=1
-------HHYLMFFTNTGRVYRMKAYEIPEASRTSRGTAIVNLLQPEKISAVIPIEDDEYLLMATKKGLIKKTPIKEYAN-RK--TGL---AAITLREED
ELIEVK-T---DS-HDVFMVTKYGQCIRFNE--VRPTRSMGVRGMNLV---RVIGMQIDSQGTELLIVSEYGMGKRTSIDEFTAQNRGGKGVKCYKITTG
N-VVGVKAVDD-NEIMIINTEGIIIRMKCDGISELGRVTSGVKLINLPEG--DKVACIAKVR--------------------------------------
------------
>tr|R7IMU5|R7IMU5_9FIRM DNA gyrase subunit A OS=Roseburia sp. CAG:303 GN=gyrA PE=3 SV=1
-------HHNLMFITNTGKAYRIKAYEIPDASRTSRGVAIINLIQPEKVTAMFPVKENSFLTMVTKNGIVKKTPMVEYAN-RK--RGL---QAICLREDD
ELIEVK-T---LN-DIVMLVTKYGQCIKFKV--IRRTRSIGVRGINLD---HVIGMQLESQGECLLLVTENGMGKRTLASEFTVQHRGGKGVKCYRINTG
N-IIGVKSVDD-NEIMLITTEGIIIQMQVSGISRLGRITSGVKLMDISGD--IVVASIAKVR--------------------------------------
------------
>tr|C3WFJ3|C3WFJ3_FUSMR DNA gyrase subunit A OS=Fusobacterium mortiferum ATCC 9817 GN=gyrA PE=3 SV=1
-------LDTLMIFTNQGRVYNIKVYEIPES-KQSRGRLIGNIINTEKIRAIIKTR-ENEVIFVTKDGTVKKTNLSEFKNINS--SGL---KAIKLKEND
DIIYVGLI---EDNEQLLIATQAGYSIRFS---LRATRTMGVKGLTLR---TVVSALLIKDNSSILTITENGYGKRTKIDEYPLQSRIGKGVINLRCSTG
S-VVSVLSVS-DEELMAITSSGVVIRIAVDDIVL-GRATQGVIIMKVHGKD-EKVVSITRVK--------------------------------------
------------
>tr|U7VDG4|U7VDG4_9FUSO DNA gyrase subunit A OS=Cetobacterium somerae ATCC BAA-474 GN=gyrA PE=3 SV=1
-------LDTMMIFTDKGRVFHLKVYQIPESSKQARGRLIGNLIKEEKVREIIKIR--KELVFVTRDGMVKKTNLSEYKN-NT--AGL---KAIKLRDGD
DIIFVG-L---PVKEQIFLATKLGHSIRFAK--VRPTRTSGVKGISLR--DKVISALLIDDNETILTITENGYGKRTRVDEYPLQSRSGKGVINIRCSNG
E-VVAVKPVKE-EELMVITSSGIVIRTSVNQISIIGRATQGVKIMRVNESS-EKVVSIASFK--------------------------------------
------------
>tr|D1AIT4|D1AIT4_SEBTE DNA gyrase subunit A OS=Sebaldella termitidis (strain ATCC 33386 / NCTC 11300) GN=gyrA PE=3 SV=1
-------LDSLLIFTTKGKVHDIKVYEIPEASKQARGRLISNIIKEEMVSTIIKVR-DKDIFFVTRKGVVKKTNLELFAS-NK--AGI---KAIGLKDDD
ELIFAG-T---SGKDEIFLATREGFAIRFSE--VRSMRASGVKGITLR--DVIVAGAIIYAGKTILTISEEGYGKRTKLEEYRLQSRGGKGITNLKKNTG
K-ISDVKIVDS-SEIMLITSEGTLIRTQVNSISIIGRATSGVRIMKVREN--EKVASTVKIT--------------------------------------
------------
>tr|H1PXM9|H1PXM9_9FUSO DNA gyrase subunit A OS=Fusobacterium ulcerans 12-1B GN=gyrA PE=3 SV=1
-------LDTLMIFTNQGRVFNIKVYEIPES-KQSRGKLMSNIIREEKIRAVIKTR-ENEVVFVTKEGLIKKTNLDEFKNINN--SGL---KAIKLKEED
DIIYVGLI---EKQEQVFIATKQGYSIRFN---VRPTRTMGVKSITLR---SIVSALLIKDEGSILTVTENGYGKRTRIDEYPLQARSGKGVINIRCNTG
A-VVSVLPVT-GEELMAITSSGIVIRMPLDTIAL-GRATQGVIIMKVDGAE--KVVSITRVK--------------------------------------
------------
>tr|W4F8D9|W4F8D9_9BACL DNA gyrase subunit A OS=Viridibacillus arenosi FSL R5-213 GN=gyrA PE=3 SV=1
-------HDTIVFFTSKGKAFRAKGYEIPEYGRTAKGLPIVNLLSKEQVTAMIRVPDDAYFIFTTRTGVTKRTPVSYFAN-RN--NGL---IAISLREDD
ELISVR-T---DG-KEIIIGTRNGMLVRFNE--IRSMRAAGVRGIRLK--DDVVGMEMIEPGQEILVVTEKGYGKRTPEEEYRIQSRGGVGIKTCQITNG
P-LSAVKTVDS-EDLMLITINGMLIRMDINDISVTGRSTQGVRLIRLGD-E-ELVATVAKVA--------------------------------------
------------
>tr|A0A078LZ47|A0A078LZ47_9BACI DNA gyrase subunit A OS=Lysinibacillus sp. 13S34_air GN=gyrA PE=3 SV=1
-------HDTILFFTTKGKVFRAKGYEIPEYSRTAKGLPIINLLNKESVTAMIRVPEDAYFIFTTKTGVTKRTAVSNFAN-RT--NGL---IAISLREDD
ELMAVR-T---DG-QEIVIGTRQGMLIRFLE--IRSMRAAGVRGIRLR--DDVVGMEIIESGQDILVVSEKGYGKRTNEDEYRTQTRGGIGIKTMQITTG
P-LVAVKTVTE-EDIMLITVEGMLIRMDVNDISTIGRNTQGVRLIRLAE-E-EYVATVAKVK--------------------------------------
------------
>tr|A0A0A3IR31|A0A0A3IR31_9BACI DNA gyrase subunit A OS=Lysinibacillus boronitolerans JCM 21713 = 10a = NBRC 103108 GN=gyrA PE=3 SV=1
-------HDTILFFTSKGKVFRAKGYEIPEFGRTAKGLPIVNLLNKEKVTAMIRVAEDAYFIFTTKTGITKRTPVSQFAN-RT--NGL---IAISLREDD
DLISVR-T---DG-KQVIIGTRDGMLVRFQE--IRSMRAGGVRGIKLR--GDVVGMEIVEPGQEILVVTEKGYGKRTSEEDYRLQSRGGVGLKTIQITNG
P-MVAVKTVDS-EDLMLITINGMLIRMDVNDISLIGRSTQGVRLIRLGD-D-ELVATVAKVE--------------------------------------
------------
>tr|A0A0M3RCQ8|A0A0M3RCQ8_9BACI DNA gyrase subunit A OS=Bacillus sp. FJAT-22090 GN=gyrA PE=3 SV=1
-------HDTILFFTNKGKVYRARGFEVPEYGRTAKGLPIVNLLGREQVTAMIRMAEDNYFIFTTKHGVTKRSPVSGFAH-RA--NGL---IAISLRDED
ELIAVR-T---DG-KQIIIGTRQGKLVRFEE--IRSMRASGVRGVRLK--DDVVGMEIIEPGQEILVVTENGYGKRTPESEYRLQSRGGMGVKTCQITNG
P-LCAVKAVDT-EDLMLITINGMLIRMDVNDISVTGRSTQGVRLMRLAG-D-ELIATVAKVK--------------------------------------
------------
>tr|A0A0P6WNR6|A0A0P6WNR6_9BACI DNA gyrase subunit A OS=Bacillus vietnamensis GN=AM506_19880 PE=4 SV=1
-------HDTILFFTNKGKAYRAKGYEIPEFSRTAKGLPIINLLGKEWINAMIRVEDDWYLFFTTKQGISKRTPVSDFAN-RT--NGL---IAINLREND
ELISVK-T---DG-KDMIIGTKQGMLIRFPE--VRSMRATGVKGINLS--DDVVGMEILEDKSDVLVVTVNGYGKRTPASEYRVQTRGGKGLKTCNVTNG
E-LVSVKAVTE-EDLMIITAHGVLIRMDVNDISTTGRNTQGVKLIRLQE-S-EFVSTVAKVE--------------------------------------
------------
>tr|A6CPM5|A6CPM5_9BACI DNA gyrase subunit A OS=Bacillus sp. SG-1 GN=gyrA PE=3 SV=1
-------HDTILFFTNKGKAFKAKGYEIPEFSRTAKGIPIINMLGKEWVNAMIRIEDDWYLFFTTKQGISKRTPVSDFAN-RT--NGL---IAINLREND
ELISVK-T---DG-KDIIIGTQKGMLIRFPE--VRSMRATGVKGINLD--EDVVGMEILEEKDDVLVVTEKGFGKRTPAEEYRIQTRGGKGLKTCNITNG
E-LISVKAVTE-EDLMLITAHGVLIRMDVNDISITGRNTQGVKLIRLDE-N-SSVATVAKVE--------------------------------------
------------
>tr|G2MH37|G2MH37_9ARCH DNA gyrase subunit A OS=halophilic archaeon DL31 GN=gyrA PE=3 SV=1
-------HDYLLCFTNHGQVYELKTYQVPEMSRTARGKSAVNLLDEEQLEAVVNTADDQFLTMVTRDGYIKRTGVSEFQNILS--TGI---RAIRLEDGD
SLADVEVT---DGTQDVVIATKGGMSIRFDE--ARAMRARGVRGVKLE---EVAAVAGIDENSWLLTVTENGYGKRSNLDAYRTQSRNGKGLIDI--NNG
P-VSALEAVGPGDHLVMMSEEGQIMRSPVEDLSIVGRNTMGVIVMRVDD-G-DRVAAVDVIE--------------------------------------
------------
>tr|A0A0P7GC22|A0A0P7GC22_9EURY DNA gyrase subunit A OS=Halolamina pelagica GN=SY89_02180 PE=4 SV=1
-------HDYLLCFTNHGQVYKLKTYEVPEMSRTARGKSAVNLLDDEQIESVVN--EQQFLTMVTRGGYIKRSGVSEFQNILS--TGI---RAISLEDGD
RLADVE-T---DGAQDVVIATRNGMSIRFDE--ARAMRARGVRGVDLE---DVAAVAGIDENSWLLTVTENGYGKRSDLDAYRVQSRNGKGLIDI--NNG
G-VTALDAVGPGDHLVTMSEQGQIMRCPVEDLSIVGRNTMGVTVMDLEA-G-DRVAAVDVVD--------------------------------------
------------
>tr|C0BFK2|C0BFK2_9FIRM DNA gyrase subunit A OS=Coprococcus comes ATCC 27758 GN=gyrA PE=3 SV=1
-------HQYIMFFTNTGRCYRLKGYEIPEAGRTSRGTAIINILQPEKITAMIPIKEGDYLFMATKKGLVKKTPILDYAN-RK--TGL---AAITLREDD
ELIEVK-T---DD-RDVILVTQYGQCIRFHE--VRSTRSMGVRGMNLS---RVVAMQLDAQGEELLIVSEKGMGKRTRMEEFTAQNRGGKGVKCYKITTG
N-VVGAKAVGD-DEIMIINTDGIVIRMECAGISVLGRITSGVKLINLKEH--EEVASIAKVR--------------------------------------
------------
>tr|K4MTS0|K4MTS0_9EURY DNA gyrase subunit A OS=Methanolobus psychrophilus R15 GN=gyrA PE=3 SV=1
-------HNYILFFTSKGRVYWQKVYEIPEGSRQSRGKAIVNLLEEESVTAMIPVS-DSYLFMATRMGTVKKSSLSDFSN-RK--AGI---IALNLDEGD
ELVNVA-T---DG-KEMVMVSRHGKAIRFSE--VRPMRARGVRGMRLE--DLVVSLDVVDE-ASLLTVTENGFGKRTEFGEYRTLHRGGQGVITIVTSNG
P-VMNVKAVKT-DEIMLTSSEGIIIRIPVKDIRIQGRNTQGVKIMDVRQK--DKVVGVARIR--------------------------------------
------------
>tr|F7XMZ5|F7XMZ5_METZD DNA gyrase subunit A OS=Methanosalsum zhilinae (strain DSM 4017 / NBRC 107636 / OCM 62 / WeN5) GN=gyrA PE=3 SV=1
-------HDDLLFFTNKGRVYCQKVYEIPQASRHSRGKAIVNLLD-EFITAMIPIS-DSYLLMATKQGTVKKCQLSEFSN-RK--TGI---IAISLNDED
ELSNVI-T---DS-RDVILVSRNGKAIRFSE--VRTMRARGVRGMKLD--DMVVSIDVVDEDSTLLTVTEKGFGKRTRFGEYRTMRRGGRGVMTIVTSNG
H-VVNIKSVKN-DEVMLTTSEGIIIRIPVKDIRIQGRNTQGVKIMHVRSD--DKVVDVAKIR--------------------------------------
------------
>tr|Q12YR8|Q12YR8_METBU DNA gyrase subunit A OS=Methanococcoides burtonii (strain DSM 6242 / NBRC 107633 / OCM 468 / ACE-M) GN=gyrA PE=3 SV=1
-------HDYLMFFTNRGKVHWKKVYGLPEGSRQSKGKAVVNLLDEESVTATITVK-DKFLFMATRMGTVKKTPLSDFSN-RK--AGI---IALKLDEGD
ELVNVA-T---DG-KEIMMVSRHGKAIRFCE--VRPMRARGVRGMRLT--DIVVSLDIVDL-TKLLTITENGYGKRTTFDEYRGMKRGGQGVITIVTSNG
P-VINVKAVKE-DEVMVTSSEGIFIRIPVKDIRAQGRNTQGVKIMNVRPG--DKVVGVARIK--------------------------------------
------------
>tr|D7E9I1|D7E9I1_METEZ DNA gyrase subunit A OS=Methanohalobium evestigatum (strain DSM 3721 / OCM 161 / Z-7303) GN=gyrA PE=3 SV=1
-------RDYLLLFTNKGRVNCKKVYEIPQGSKQSRGKALVNLFENEAVSSMITVK-DWNLLMATKYGTVKKTPLSSFKT-KK--SGL---IAINLNEND
ELVNVI-T---DG-NDIILVSSTGKAIRFAE--VRPMRAQGVRGIRLN--DRIISMDTISDNAKLLTITQNGYGKRTKFEEYRRMNRGGRGVTTIQMTNG
P-VVNVKTVRD-DDIVVTSYQGLVIRIPVKDIRVQGRNTQGVKIMNMRE-N-DKVIGVARIK--------------------------------------
------------
>tr|L0KX58|L0KX58_METHD DNA gyrase subunit A OS=Methanomethylovorans hollandica (strain DSM 15978 / NBRC 107637 / DMS1) GN=gyrA PE=3 SV=1
-------HDYIMFFTNKGRLYWKKVYEIPEGSRQSKGKAIVNLLEEEYVTAMIPVK-DQYLFMATRSGTVKKTSLSDFSN-RK--GGI---IAVTLLEDD
ELVNVA-T---DG-KDVVLVSRHGKAIRFSE--VRSMRAQGVRGIKLE--DKVVSLDVVDE-STLLSITENGFGKRTEFGEYRTMRRGGMGVITIVTSNG
P-VVNVKAVRE-DEVMITSSEGIVIRIPVTDIRIQGRNTQGVKIMDVRQG--DKVVGVARIE--------------------------------------
------------
>tr|A0A0E3SRU3|A0A0E3SRU3_METMT DNA gyrase subunit A OS=Methanococcoides methylutens MM1 GN=gyrA PE=3 SV=1
-------HDYLMFFTNRGRVHWQKVYGIPQGSRQSKGKAIVNLLEEESVTAMIPVK-DKYLFMATRSGTVKKSSLSDFSN-RK--AGI---IAIKLDEGD
ELVNVA-T---DG-REIMMVSRHGKAIRFSE--VRSMRARGVRGMKLA--DIVVSLDIVDS-SKLLTITENGYGKRTSFDEYRGMRRGGQGVITIVTSNG
P-VINVKAVHD-DEVIITSSDGIIIRIPVKDIRSQGRNTQGVKIMNVKAG--DKVVGVARIK--------------------------------------
------------
>tr|W9DTR5|W9DTR5_METTI DNA gyrase subunit A OS=Methanolobus tindarius DSM 2278 GN=gyrA PE=3 SV=1
-------HDYIMFFTNQGRVHWRKVYEIPEGSRQSRGKAIVNLLEEELVTAMIPVN-DEFLFMATRTGTVKKSQLSDFSN-RK--KGI---IAISLVEGD
ELVNVA-T---DG-REMMMVSQHGKAIRFPE--VRVMRAKGVRGMNLE--DMVVSLDVVDD-TALLTITENGFGKRTEFDEYRAMHRGGRGVITIVTSNG
P-VINVKAVHD-DDVILTSSEGIIIRIPVKDVRIQGRNTQGVKIMNVRAS--DKVVGVARIR--------------------------------------
------------
>tr|M0CPJ9|M0CPJ9_9EURY DNA gyrase subunit A OS=Halosimplex carlsbadense 2-9-1 GN=gyrA PE=3 SV=1
-------HDYLLSFTNQGQVYKLKTYEIPEMSRTARGKSAVNLIDDEEITAVVNTD-EESIAMVTRDGYVKRTNAEEFENILS--TGI---IAADLEEGD
ELVDVEVT---DRTKDLVIATEQGMTIRFDE--AREMRARGVGGIDLQ---HVAGMVATDEDRCLLTVTRNGYGKRTPLTEYRRQSRYGKGLIDI--DNG
P-VSTVKAVRTDDHLMIMSERGQIMRIRAGDVSEVGRNTKGVVVMKLED-G-DQVASVDVVP--------------------------------------
------------
>tr|A0A0R1YN54|A0A0R1YN54_9LACO GyrA protein OS=Lactobacillus amylophilus DSM 20533 = JCM 1125 GN=FD40_GL001478 PE=4 SV=1
-------HDYLLFFTNTGKVYSKKAYEIPEFGRSAKGIPIINLLNEEQVQAVINIS-DKYLFFVTKLGTVKRTEVAEFTN-RK--SGL---RALTLKEDD
ELSNVI-T---DG-QIIFIGTHHGYAVTFKE--IRSMRASGVRGIRLR---NVVGSEVLRPDSEVLVISENGYGKRTPSSEYPVKGRGGKGIKTANITNG
P-LAGITIVDT-EDLMLITDAGVLIRFKVANVSQTGRATLGVRLIRVDDG--TKVAGMTKVP--------------------------------------
------------
>tr|F4KUQ9|F4KUQ9_HALH1 DNA gyrase subunit A OS=Haliscomenobacter hydrossis (strain ATCC 27775 / DSM 1100 / LMG 10767 / O) GN=gyrA PE=3 SV=1
-------HHYLLLFTSAGRCYWLKGYEIPEAAKTATGRAIQNILAKDKVKAFIVIEDNHYIMFCTQQGVIKKTPVEAFSR-RA--GGI---NAITINEGD
QLLEAWLT---GGNHEVFLASRRGYAVRFN---VRSMRAAGVRGMTLADG-DVVGMVCIAPESTLLVVSEKGNGKRSEVEEYRLTKRGGKGVKTIQITTG
M-LVAIKSVK-DDDLMITNRSGIIIRMAIGGLRVMGRATQGVRVIRLDD-D-DDIADVTVVK--------------------------------------
------------
>tr|M9L863|M9L863_PAEPP DNA gyrase subunit A OS=Paenibacillus popilliae ATCC 14706 GN=gyrA PE=3 SV=1
-------HHYLMFFTDKGKVYRIKAYEVPGLSRTSRGTPIINLIQQEAVNAVIPVKADKFLFFATRYGIVKKTPLDDYVN-RK--GGL---IAINLREDD
DLIGVR-T---DG-QEIIMGTSNGMSIRFPE--VRSMRATGVKGITLD---DVIDMDVVSEDNDVLIVSSKGYGKRTPMSEYRIQSRGGKGIKTINVTNG
P-VIGLKVVQE-EDLMIITSLGTIIRMSMAGISQMGRYAQGVKLINIRED--DSVATVSRCD--------------------------------------
------------
>tr|F5SHF9|F5SHF9_9BACL DNA gyrase subunit A OS=Desmospora sp. 8437 GN=gyrA PE=3 SV=1
-------HNYLLFFSNKGKVYRMKAYEVPELSRTARGTPIINLIQQEYIEAVIPVR-DSYLFFGTKFGVVKKTPLEEFGH-RR--NGL---FAINLREGD
ELVGVR-T---DG-QEIMLGTRRGMSIRFPE--VRQMRATGVKGIALG---DVVGMEVVDPEREVVVVTSKGYGKRTPLSEYRTQSRGGKGIKAQNVTKG
H-VVGLKVVSD-EDLMIVTDSGVVIRMNIDGISRMGRYAQGVKLISVKQD--EEVASLARVP--------------------------------------
------------
>tr|A0A074LJF2|A0A074LJF2_9BACL DNA gyrase subunit A OS=Tumebacillus flagellatus GN=gyrA PE=3 SV=1
-------HNYLLFFTNRGKAYRIKAYEVPEFGRAAKGTPIINVLNQEMVSAVIPLENGPFLFLATRRGIVKKTPLTAYQN-RK--AGL---IALTLKDED
ELIGVK-T---DG-RNIILGTRNGMSVHFPE--VRSMRAAGVKGIELD---GVIDMDVTNDNCHVLVVSSKGYGKRSPIDSYRIQGRGGRGLKTIDRTTG
H-IAGLKVVTE-DDIMVITNTGVVIRMAVNTISELSRITQGVKLITLHDEE-EEVSTVARVP--------------------------------------
------------
>tr|W8YNM2|W8YNM2_9BACL DNA gyrase subunit A OS=Paenibacillus sp. P22 GN=gyrA PE=3 SV=1
-------HHYLLFFTDKGKVYRLKAYEIPDLSRTARGTPIINLLQQETVNAVIPVEPDCYLFFGTRQGIVKKTPLDDYSN-RR--VGL---IAINLREDD
DLISVK-T---DG-QEIIIGTADGMSIRFPE--VRSMRATGVKGIALD---DVIDIDVVDPEQEVLIVTAKGYGKRTPVSEYRTQSRGGKGIKTLNVTNG
P-IAGLKMVEG-EDLMIMTASGTMIRMNMDTISSMGRNTQGVRLINIRDE--DSVATVTRVA--------------------------------------
------------
>tr|C6IWT3|C6IWT3_9BACL DNA gyrase subunit A OS=Paenibacillus sp. oral taxon 786 str. D14 GN=gyrA PE=3 SV=1
-------HHYLMFFTDRGKAYRLKAYEIPELGRTARGTPIINLIQQETVNAVIEVEDNKYLFFATKQGIVKKTPIEDYIN-RK--GGL---IAVNLREDD
TLIDVK-T---DG-EEVIMGTAQGMSIRFPE--VRSMRATGVKGITLD---GVIGMDVVVPGQDVLIVTANGYGKRTPISEYRTQSRGGKGIKTINVTNG
T-VVGLKVVKE-EDLMIITASGTLIRTSMEGISTMGRNTQGVKLINIRED--DTVATVCRTD--------------------------------------
------------
>tr|S9SZ47|S9SZ47_PAEAL DNA gyrase subunit A OS=Paenibacillus alvei A6-6i-x GN=gyrA PE=3 SV=1
-------HHYLMFFTDKGKVYRIKAYEIPDLSRTARGTPIINLIQQESISAVIPVVSDKYLFFATRQGIVKKTPLDDYVN-RK--GGL---IAINLRDDD
ALIGVR-T---DG-QEIIMGTKMGMSIRFSE--VRSMRATGVKGITLD---EVIDMDVVNKENDVLIVTAKGYGKRTPMEDYRIQSRGGKGIKTINVTNG
A-VVGLKVVQG-EDLMIITASGTIIRTSMSGISQMGRYTQGVKLINIRDD--DSVSTVSRCD--------------------------------------
------------
>tr|F4XIF5|F4XIF5_9CYAN DNA gyrase subunit A OS=Moorea producens 3L GN=gyrA PE=3 SV=1
-------HDSILFFSDRGVVYSLRAYQIPAVSRTARGVPIVQMLPHEKITSIVPVSDDEYLVMLTHKGYIKKTALDAFSKIRA--NGL---IAISLGEGD
QLRWVLRA---REEDSIIIGSRHGMAIHFKC--LRPLRTRGVKAMKLK---DLIGMDILSGGPWVLIVTMGGYGKRVPVSQFRLQNRAGMGVRSTKFPKD
Q-LAALQVVN-GDELMIVTSRGIIIRQAVDAISPQSRMATGVRVQKLDD-E-DAIAAVALVP--------------------------------------
------------
>tr|B4VPJ9|B4VPJ9_9CYAN DNA gyrase subunit A OS=Coleofasciculus chthonoplastes PCC 7420 GN=gyrA PE=3 SV=1
-------HDSLLFFSDRGVVYSLRAYQIPAASRTARGVPIVQMLPHEKITSVVPVSDDVYLVMLTRKGYIKKTALDAFSNIRA--NGL---IAISLGEGD
QLRWVRLC---RAEDSIIIGSSQGMAIHFKA--LRPLRTRGVKAMKLR---ELISMDILPAGPWVLVVTTGGLGKRVPVSQFRLQNRAGMGLVTIKF-KD
K-LAALRVVN-GDELMMVTMRGIIIRQALDAISPQSRMATGIRVQRLDE-E-DAIAAVALVP--------------------------------------
------------
>tr|S0K5J9|S0K5J9_9ENTE DNA gyrase subunit A OS=Enterococcus dispar ATCC 51266 GN=gyrA PE=3 SV=1
-------HDTLLFFTNVGKVYKAKGYEIPEYGRTAKGIPVINLLGDEKIQTIIAVSDNKYLFFTTLLGVVKRTSVDAFSN-RS--NGL---IAINLKEND
ELVDVL-T---SG-DTMIIGTHDGYSVTFKE--VRDMRASGVRGIRLR---NVVGVSVITPDKEVLVITENGYGKRTAGLEYPVKGRGGKGIKTANITNG
P-LAGLTTVNN-EDIMLVTNKGVIIRFNVASVSQTGRATLGVRLMKLEDD--AKVVTMAAVE--------------------------------------
------------
>tr|A0A091BXC6|A0A091BXC6_9ENTE DNA gyrase subunit A OS=Tetragenococcus muriaticus 3MR10-3 GN=gyrA PE=3 SV=1
-------HDNLLFFTNAGKVYKAKGYEIPEYGRTAKGIPVINFLGDERIQTVIALSERKYLFFTTKYGIVKRTSVEAFKN-RS--NGL---IAIGLKDQD
ELVNVL-T---CG-DVMIIGTHKGYSVTFQE--VRDMRASGVRGIRLR---EVVGAAVIRENDEVLVITEKGYGKRTAGDHYPVKGRGGKGVKTANITNG
P-LAGLTTVSN-EDVMVITDKGVIIRFRVEDISQTGRSTLGVRLMKMEED--AKVVTMATVD--------------------------------------
------------
>tr|K8ZKS6|K8ZKS6_9ENTE DNA gyrase subunit A OS=Catellicoccus marimammalium M35/04/3 GN=gyrA PE=3 SV=1
-------HDLLLFFTNKGKVFKAKGYEIPEYSRNAKGIPVINLLGEESIQSIIKVDPKQELFFVTKNGLVKRTAFAAFAN-RS--NGL---KAIQLKDED
ELIQVM-T---SG-DQIMIATHEGYSINFME--VRSMRAAGVRGIRLR---GVIGATTVSPEAQILVVTENGYGKRTEVSAYPVKKRGGKGVKTLQKTTG
G-LVALCTVTT-DDVLVMTNRGVMIRFAVDTISTIGRVAQGVRIIRLEEG--TTVSTVDIIE--------------------------------------
------------
>tr|K1MKP7|K1MKP7_9LACT DNA gyrase subunit A OS=Facklamia ignava CCUG 37419 GN=gyrA PE=3 SV=1
-------HDTLLYFTNTGRVFRTKGYDVPEYGRQARGLPIVNFLSDESIKEVIAIESDGYLFFVTQSGTVKKSNISDYFN-RQ--NGL---IALNLKEDD
EVVNVF-T---DG-QAIIIGTRHGYAMAFHE--VRPMRATGVRGIRLR---DVVAADVFNAGEEILVVTENGYGKRTAVEEYSLKNRGGLGVQTVRLSSG
Y-LTGLVSTDS-EDIMIMTDTGVVIRFDINDISQTSRVTLGVRMIRLDEG--AKVSSLTAIS--------------------------------------
------------
>tr|E6LEK2|E6LEK2_9ENTE DNA gyrase subunit A OS=Enterococcus italicus DSM 15952 GN=gyrA PE=3 SV=1
-------HDTLLFFTNAGKVYKAKGYEIPEYGRTAKGIPVINLLGDERIQAIIAVKAEQYLFFTTKLGVVKRTDVQAFSN-RS--NGL---IAIGLKEQD
ELVNVL-T---KG-DTIIIGTHGGYSVTFAE--VRDMRAAGVRGIRLR---GVVGTAILTPESEVLVITENGYGKRTASSEYPVKGRGGKGIKTANITNG
P-LAGLTTVSE-EDILVITDKGVIIRFNVATVSQTGRATLGVRLMKMENE--AKVVTMATVE--------------------------------------
------------
>tr|G5IWT1|G5IWT1_9ENTE DNA gyrase subunit A OS=Enterococcus saccharolyticus 30_1 GN=gyrA PE=3 SV=1
-------HDTLLFFTNMGKVYKAKGYEIPEYGRAAKGIPVINLLGDERIEAIISASEGRYLFFTTRLGIVKRTSVTAFSN-RA--NGL---IAIGLREND
ELVNVV-T---NG-DVMIIGTHNGYSVTFKE--VRDMRAAGVRGIRLR---DVVGASVIKEDSEVLVITENGYGKRTKGSEYPIKGRGGKGIKTANITNG
P-LAGLTTVSK-EDIMLITDKGVIIRFNAETVSQTGRATLGVRLMKMENG--AKVVTMATVD--------------------------------------
------------
>tr|R2SGE5|R2SGE5_9ENTE DNA gyrase subunit A OS=Enterococcus asini ATCC 700915 GN=gyrA PE=3 SV=1
-------HDTLLFFTNMGKVFKAKGYEIPEYGRAAKGIPVINLLGDEQIQTIIAVNSGRFLFFCTRLGIVKRTSVEAFAN-RS--NGL---IAIGLKDGD
ELVSVL-T---DG-SNIIIGTHTGYSVTFAE--VRDMRAAGVRGIRLR---EVVGVAPITPEKEVLVVTENGYGKRTSGSEYPVKGRGGKGIKTANITNG
P-LAGLTTVDD-EDIMVITDKGVIIRFNVGDVSQTGRATLGVRLMRMEDE--SKVMTMAVIE--------------------------------------
------------
>tr|Q1LT83|Q1LT83_BAUCH DNA gyrase subunit A OS=Baumannia cicadellinicola subsp. Homalodisca coagulata GN=gyrA PE=3 SV=1
-------HDTILLFSSRGRMYWMKVYQLPAASRGSRGRPIVNLLP-ERITTILPVREGCNVFMATASGTVKKTALIAFSRPRS--AGI---IAVNLHEGD
ELIGVNVT---NGNNEVMLFSAYGKVVRFPETQVRSMRATGVRGINLA--EGVVSLIIPNI-GHILTVTQHGYGKRTTQNEYPTKSRATQGVISIKASNG
Q-VIGAIQVDEHDQIMLITDAGTLVRTRVSEVSIVGRNTQGITLIRTA-EN-EHVVGLQRIA--------------------------------------
------------
>tr|A0A0G8G6C8|A0A0G8G6C8_9LACO DNA gyrase subunit A OS=Lactobacillus ruminis GN=gyrA PE=3 SV=1
-------HDDVLFFTNIGKVYRMKGYEVPEYGRAAKGIPVINLLDSEKIQTVINVDDSHFLFFTTVQGVVKRTSVTEFGN-RK--NGL---KAITLREGD
ELLNVS-T---DG-QNIIIGTHGGYAVSFSE--VRQMRASGVRGIRLR---DAVGSDVLKPDSNVFVISEKGYGKQTPASDYPIKGRGGKGIKTSNITNG
S-LAGLTIVDT-EDIMVITDKGVMIRFNVKSVSKTGRSTMGVHLINLDDD--AKVSTIAKVE--------------------------------------
------------
>tr|A0A0R2A477|A0A0R2A477_9LACO DNA gyrase subunit A OS=Lactobacillus animalis KCTC 3501 = DSM 20602 GN=FC30_GL000431 PE=4 SV=1
-------HDELLFFTNVGKVYRMKGYEVPEYGRAAKGIPVINLLDDEKIQTVINVEDSHFLFFTTVKGTVKRTFVTEFGN-RK--NGL---KAISLHDGD
ELIHVS-T---DG-QNIIIATHGGYAVSFAE--VRPMRAAGVRGIRLR---EVVGASILRPDSKVFVISEKGFGKQTPASEYPIKGRGGKGIKTTNITNG
N-LAGMTMVND-EDIMVITDKGVMIRFNLANVSQTGRATLGVKLINLDDD--AKVSTMAKVE--------------------------------------
------------
>tr|Q8D2A9|Q8D2A9_WIGBR DNA gyrase subunit A OS=Wigglesworthia glossinidia brevipalpis GN=gyrA PE=3 SV=1
-------HDSILLFSSKGRVYWMKIFQLPENSRGSIGKPIINLLP-EYITAILPFRKKLYVFMATASGIVKKTALHEFSRPRS--SGI---IAVNLNSGD
KLIGADLT---DGSQEAMLFSEYGKVVRFPENQVRNMRASGVKGISLI--PGVVSLIIPKN-SPILTVTQYGYGKRTVQSEYPTKSRAIQGVISIKVSNG
K-VVGAVQVNDYDQIMIITDSGTLVRIRVSEVSIVGRNTHGVRLIRIS-NN-NNVVGLQRVV--------------------------------------
------------
>tr|K2BPT7|K2BPT7_9BACT DNA gyrase subunit A OS=uncultured bacterium (gcode 4) GN=gyrA PE=3 SV=1
-------HDTILCFTTQGKVYWLKVYQFPQANRTSRGKPIINLLP-ERVNAFLPVRENQYVVFATSKGLIKKVSLVDFSRPRS--SGI---IAIALNEGD
YLVQADIT---DGEHDIMLFTDAGKVVRFPESKVRCMRAAGVRGVKLQD--QVVSLVVAR-DGAILTATENGYGKRTAIDEYRLSGRGGQGVISIHVNNG
K-VVGAIQVNEEDEVMLISNKGTLVRVPAAEISLIGRNTQGVRLIQLS-EG-ESLVSLERII--------------------------------------
------------
>tr|K1ZGU4|K1ZGU4_9BACT DNA gyrase subunit A OS=uncultured bacterium (gcode 4) GN=gyrA PE=3 SV=1
-------HDTILCFSNHGKVYWLKVYQLPQASRNSRGKPIVNLLP-EKINAILPVRKDQFVFMATAKGTVKKVALTEFSRPRS--NGI---IALELADND
KLIGVDIT---NGQQEVMLFTNAGKVILFSEEDVRSMRARGVRGVKLQKQY-VISLIVVH--GDILTATKNGYGKRTAIEEYRSTGRGGQGVISIQVTNG
D-VIAATQVNPVDEVMLISNKGTLVRVPVAEISLVGRNTQGVRLINLV-ND-ELLVGLERIA--------------------------------------
------------
>tr|K9YDW2|K9YDW2_HALP7 DNA gyrase subunit A OS=Halothece sp. (strain PCC 7418) GN=gyrA PE=3 SV=1
-------HDHLLFFSDRGVVYALSAYQVPIGSRTARGTPLLQMLPQEKITTVLAVREEDYLIMLTRQGNIKKTSLSAFSNIRT--NGL---IAISLADED
QLRWVRLA---KESDSIIIGSRKGMAIHFRA--LRPLRTRGVKAMKLK---DLISMDILPATLWILAITKGGYGKRVPITQFRLQNRAGKGLSAMKF-QD
C-LAALKVVH-GEELMLVTNRGIIIRQGSDAIPRQSRQATGVRVQRLDD-D-DAIAAVALVP--------------------------------------
------------
>tr|A0A075JJ18|A0A075JJ18_9BACI DNA gyrase subunit A OS=Virgibacillus sp. SK37 GN=gyrA PE=3 SV=1
-------HDTVLFFTNKGKVYKAKGYEVPEFSRTAKGIPIINMLQKEWVNAVISVNDDNYLFFTTKHGISKRTTLTQFAN-RK--GGL---IAVGLRDED
ELISVR-T---DG-QDIMIATKNGYLIRFEE--IRSMRAAGVKGISLR--GDVVSMEILQEDSNILHVTNKGYGKQTPENEYRRTNRGGKGVFTCNLTTG
L-VVAVKAVSD-EDLMMITVAGVLIRIPVKDISETGRNTMGVRLIRLQE-N-EEVATVASVD--------------------------------------
------------
>tr|K0IUW9|K0IUW9_AMPXN DNA gyrase subunit A OS=Amphibacillus xylanus (strain ATCC 51415 / DSM 6626 / JCM 7361 / LMG 17667 / NBRC 15112 / Ep01) GN=gyrA
-------HDTILFFTNKGKVYRLKGYQIPEYGRAAKGLPVINILEKEWVNTVISAPEDKFLFFTTKHGISKRTSLNQFAN-RR--NGI---IALTLRDED
ELISVQ-T---DG-KDIMIATRNGYLIRFDE--IRSMRAAGVKGISLR--DDVVSMEIVEENDYILNVTENGYGKRTPESDYRMINRGGKGVFTANVTTG
S-VVAVKSVND-EDLMIMTDSGVLIRTPIEAISITGRNTQGVRLIRLQE-D-QKVATVACVE--------------------------------------
------------
>tr|A0A0P7J7X9|A0A0P7J7X9_9BACI DNA gyrase subunit A OS=Lentibacillus amyloliquefaciens GN=AOX59_11620 PE=4 SV=1
-------HDTILFFTNKGKVYRAKGYEVPEFSRTAKGIPIINLLQKEWINAVISVAEDYFLFFTTRYGLSKRTKLSQFAN-RK--GGL---IAVGLRDED
ELISVR-T---DA-KDIMMGTKNGYLIRFPE--VRSMRAAGVRGISLR--DDVVSMEILDKGVEVLHVTNKGIGKRTPEEQYRITNRGGKGIFTCKLAN-
E-VVAVKAVTD-EEIMLITVAGVLIRIPVEGISQTGRNAQGVRLIRLND-N-EEVATVAKVD--------------------------------------
------------
>tr|A0A0L0QRE0|A0A0L0QRE0_VIRPA DNA gyrase subunit A OS=Virgibacillus pantothenticus GN=gyrA PE=3 SV=1
-------HDTILFFTNKGKVYKAKGYEIPEFSRTAKGIPIINLLQKEWVNAVISVNDDQFLFFTTKHGISKRTSLAQFAN-RK--GGL---IAVGLRDED
ELISVR-T---DG-KDIMIATKNGYLIRFPE--VRPMRAAGVKGISLR--DDVVSMEILQEDAKILHVTNKGFGKQTPESEYRITNRGGKGIFTCNLTTG
H-VVAVKAVSE-EDLMLITVAGVLIRIPVESISVTGRNTMGVRLIRLHD-E-EEVATVARID--------------------------------------
------------
>tr|A0A0A1MBA6|A0A0A1MBA6_9BACI DNA gyrase subunit A OS=Oceanobacillus oncorhynchi GN=gyrA PE=3 SV=1
-------HDTVLFFTNKGKVYKTKGYEVPEFSRTAKGIPIINLLQKEWVNAVISVTEDHFLFFTTKLGVAKRTSLEKFKN-RK--GGL---IAVNLREED
ELISVR-T---DG-KEIMIATKNGYLIRFEE--MRPMRAAGVKGISLR--DDVVSMEIMDEGSKILHVTSKGFGKQTPEDEYRRINRGGKGVFTCKLDTG
H-VVDVKAIQD-EDLMVITAGGVLIRMQVSDISQTGRNTKGVHLIRLQD-D-EEVATVARIE--------------------------------------
------------
>tr|Q8EU82|Q8EU82_OCEIH DNA gyrase subunit A OS=Oceanobacillus iheyensis (strain DSM 14371 / JCM 11309 / KCTC 3954 / HTE831) GN=gyrA PE=3 SV=1
-------HDTILFFTNKGKVYKAKGYEIPEFSRTAKGIPIINLLQKEWVNAVISVNEEAYLFFTTKHGIAKRTSLEKFRN-RK--GGL---IAVGLREED
ELISVR-T---DG-KEMMIATKNGYLIRFEE--IRSMRAAGVKGISLR--DDVVSMEIIEPGSKILHVTNKGFGKQTDESEYRRINRGGKGVFTCKLDTG
N-VVAVKAVND-EDLMLITIAGVLIRIQVQDISQTGRNTKGVHLIRLQD-G-EEVATVTRIE--------------------------------------
------------
>tr|A0A0K0G6D7|A0A0K0G6D7_9FIRM DNA gyrase subunit A OS=Bacilli bacterium VT-13-104 GN=gyrA PE=3 SV=1
-------HDTILFFTNKGKVYRAKGYEVPEFSRTAKGIPIINMLQSEWVNAVISVSEEAYLFFTTKFGITKRTSLSMFAN-RK--GGL---IALGLREDD
ELISVK-T---NG-KDIMIATKQGYLIRFEE--IRAMRAAGVRGISLR--DDVVSMEVLEEGSHILHVTNKGYGKQTPESEYRRINRGGKGVITCKLNTG
H-VSAVKAVNE-EDLMVITVGGVLIRIPVKDISITGRSTMGVRLIRLHD-D-EEVATVAKIE--------------------------------------
------------
>tr|A0A024Q7D7|A0A024Q7D7_9BACI DNA gyrase subunit A OS=Virgibacillus sp. Vm-5 GN=gyrA PE=3 SV=1
-------HDTVLFFTNKGKVYKAKGYEVPEFNRTAKGIPIINLLQKEWVNAVISVKEDHFLFFTTKYGISKRTSLAQFAN-RK--GGL---IAVGLREED
ELISVR-T---DG-KDMMIATKNGYLIRFPE--IRSMRAAGVKGISLR--DDVVSMEIVQKDAKILHVTSKGYGKQTPESEYRVTNRGGKGIFTCNLTTG
H-VTAVKAVSE-EDLMVITVDGVLIRIPVVDISETGRNTMGVRLIRLRD-D-EAVATVTRID--------------------------------------
------------
>tr|H6RJA6|H6RJA6_BLASD DNA gyrase subunit A OS=Blastococcus saxobsidens (strain DD2) GN=gyrA PE=3 SV=1
-------HDWILFFTNKGRVYRSKAYELPEANRTARGQHVANILAPEKIAQVMQIKAP-YLVLATAKGQVKKTRLTDFDS-RQ--GGV---IAINLRD-D
ELVGAA-----DNASDLLLVTRKAMSIRFTT--LRPMRTEGVRGIALS-D-DLLSLMVVQEGVDVLVATERGFAKRTGIENYPNQGRGGKGVLTADPKKG
A-LVGALSVTG-DELYAITSGGGVIRTPVNGVRHKDRATMGVKLMNLPE-D-VSIVAIARTT--------------------------------------
------------
>tr|A0A0M9UFF9|A0A0M9UFF9_9BACT DNA gyrase subunit A OS=Candidatus Symbiothrix dinenymphae GN=gyrA PE=3 SV=1
-------HATMLFFTQKGRCFWMKVYQIPEGTKTSKGRAIQNLLSADSVSAFVRVKASNYLIFCTKKGIIKKTSLEAYSR-RQ--NGV---NAISLREGD
ELINVRLT---NGTNDIIIANRKGLAIRFN---VRRMRAAGVRGQKLS---DIVGMIVIKNDDHILVVSEKGYGKRSDL-EYRVTNRGGKGVKAMKITTG
P-LVTIKTVT-DNDLMIINKSGMTIRLKIANLNIIGRATQGVRLINLDKRN-DEIASVCVVA--------------------------------------
------------
>tr|B6YS22|B6YS22_AZOPC DNA gyrase subunit A OS=Azobacteroides pseudotrichonymphae genomovar. CFP2 GN=gyrA PE=3 SV=1
-------HAMMLFFTRKGRCYWLKVYQIPAGAKTSKGRAIQNLLNTDKVSAFIRVKESHYLVFCTKRGIIKKTLLNAYSR-RQ--NGV---KAITVHDGD
EVIAVKMT---NGNNEIIVANRKGRALRFN---VRSMRAAGVISMTLDV--DIIGMIIINDRENVLVVSEQGYGKRSRVGDYRIVNRGGKGIKTLNITTG
F-LVSIKNVT-HNDVMIINKSGIAIRIKVSDLNVIGRATQGVRLINLEKRG-DEIASVCKVM--------------------------------------
------------
>tr|C7LWV9|C7LWV9_DESBD DNA gyrase subunit A OS=Desulfomicrobium baculatum (strain DSM 4028 / VKM B-1378) GN=gyrA PE=3 SV=1
-------HQYMNLFSNKGKMYQVKVHQIPEGGRTARGKHVANLL-SEYIAAAMTCRQEKFYFFYTKLGVVKRSSVHLYRNIRA--VGL---IALGMRDDD
ELIGVR-V---ETNDEMVLVTVDGYSIRFAC--VRAMRATGVKGLALR---DVVAGVVVNKQQELLTIAENGYGKRTQVEHFRAQSRGGKGIINM--TTG
K-VVGAMMVYPTDELILLTSGSKIIRIGISDISLVGRATQGVRLVRLED-E-QTVVCFDHVP--------------------------------------
------------
>tr|C8X5Q8|C8X5Q8_DESRD DNA gyrase subunit A OS=Desulfohalobium retbaense (strain DSM 5692) GN=gyrA PE=3 SV=1
-------HQYLLLFTNKGRMHQLKVYQIPEGRRTARGTHIANLL-KEYVATVLCMKANHSFLFATKKGMVKRSAVHLYRNYRP--HGL---IAVNLRDGD
ELIAVR-V---DEESEIFLITHHGVAIRFAC--VRSMRAAGVKGIALR---DVVSCVIINGRDQLLTVSEQGYGKRTAIDYYRQQSRGGKGIINM--TTG
G-VLGAMMVDETDELIMLTSMHKMLRIGTADIRICGRATQGVKLVSLDS-E-ATVVCFDRIV--------------------------------------
------------
>tr|D6SP73|D6SP73_9DELT DNA gyrase subunit A OS=Desulfonatronospira thiodismutans ASO3-1 GN=gyrA PE=3 SV=1
-------HKDIYLFSNTGKSYLLKAYEIPEGSRTARGVHIKNLL-NEYIATALSERQRHYFLFVTKKGMVKKTSIEMFKNMRS--LGL---IAVNLKPGD
ELIGVK-V---KDESEVIITTHDGLAIRFAC--LRAMRAAGVKGISLR---DVVSGAVLDPARELFTISEKGFGKKTSLDMYKLQARGGKGLINM--TTG
K-VVSSMPVSDQEELIIFTSANKIIRLGTSDIRSVGRSTQGVKMVDLEN-D-QKVICADLII--------------------------------------
------------
>tr|C6BUN7|C6BUN7_DESAD DNA gyrase subunit A OS=Desulfovibrio salexigens (strain ATCC 14822 / DSM 2638 / NCIB 8403 / VKM B-1763) GN=gyrA PE=3 SV=1
-------HQYLLLFTSKGKMFKIKVHQVPEASRIARGAHIANLL-KETIATAMTMREECFFLFVTKSGMIKRSSIALYRNCRQ--SGI---RAVALKEGD
ALITVK-V---SADSEAVLVTRNGTSIRFSC--ARAMRASGVKGIALR---DVVSGVVTGDRVQLLTISEGGYGKRTDIDQHRIQTRGGKGIISM--TTG
K-VLGSIMVSPEDEVVLLTSGNKIIRMGVKDVSLVGRATQGVRLVRMDD-G-DHVVGFDLVQ--------------------------------------
------------
>tr|L0RA54|L0RA54_9DELT DNA gyrase subunit A OS=Desulfovibrio hydrothermalis AM13 = DSM 14728 GN=gyrA PE=3 SV=1
-------HQFLVLFTTKGKMFKIKVHQVPEASRIARGAHIANLL-KESIATALTMREDRFFLFVTRNGMVKRSSIALYRNCRQ--SGI---RAVSMKEED
QLITVQ-V---NIDSEAVLVTKNGTSIRFSC--ARAMRASGVKGIALR---DVVSGVVTGDRVQLLTVSEGGYGKRTDIEQHRLQTRGGKGIISM--TTG
K-VLGSIMVSVDDEVVLLTSANKIIRLGIKDVSLVGRATQGVRLVRMDD-D-DQVVGFDLVI--------------------------------------
------------
>tr|V6M1Q4|V6M1Q4_9BACL DNA gyrase subunit A OS=Brevibacillus panacihumi W25 GN=gyrA PE=3 SV=1
-------HDTIMFFTNKGKAYRLKGYEIPDLSRTAKGTPIINLIQKERVSAVIPVKGDRYLFFATKKGIIKKTELSSYEN-RR--VGL---IAVNLREND
ELIGVR-T---DG-QEIIMGTKNGMSVRYKE--VRTMRATGVKGITLD---DVIDMDVIKPGAEVLIVTANGYGKRTPVDEYRIQSRGGKGIKTHNVTSG
H-VVGLKVVEE-EDLMIITTSGIIIRTEMKGISVMGRYTQGVKLIRLSEN--EQVGSVAKVP--------------------------------------
------------
>tr|A0A075QXV2|A0A075QXV2_BRELA DNA gyrase subunit A OS=Brevibacillus laterosporus LMG 15441 GN=gyrA PE=3 SV=1
-------HDTLLFFTSKGKVYRLRGFEIPDLSRTAKGTPIINLIQKETVSAVIPVKEDQFIFFATKQGIVKKTDLKSFEN-RR--GGL---FAVNLREDD
ELINVR-T---DG-QQIIMGTKQGMSVRFNE--VRTMRATGVKGITLD---NVIGMDVIRDDAEVLIVTAKGYGKRTPVSEYRIQTRGGKGIKTHNVTSG
Q-VVGLKVVQD-EDLMIVTITGIIIRMEIKGISVMGRYTQGVKLIRLGDE--EEVVSIATVE--------------------------------------
------------
>tr|F5YNX0|F5YNX0_TREPZ DNA gyrase subunit A OS=Treponema primitia (strain ATCC BAA-887 / DSM 12427 / ZAS-2) GN=gyrA_2 PE=3 SV=1
-------HEYIMFITNAGKSYWMKVHELPEGSRTSKGAHIKSLLTPEDITAIVAL-DEQFLFMGTARGVVKKVAASEFSNAKT--RGI---IAIKLDEGD
KLVSALLT---GGSDEVVLISRKGQALRTHE--VRAMRSRGVTGMKLD---ELTGLLRVVEAEKMLILSEYGYGKRVDFSEFSSHGRGTGGQKIY--GTG
E-LVGCVNVLDNEEIMCITSQGKSIKLKVDSIRVMGRSAQGVRILSIDK-P-DFVIGVDRIV--------------------------------------
------------
>tr|F5YGG7|F5YGG7_TREAZ DNA gyrase subunit A OS=Treponema azotonutricium (strain ATCC BAA-888 / DSM 13862 / ZAS-9) GN=gyrA_2 PE=3 SV=1
-------HEYIMFITNEGKAYWMKVHELPEGTRTSKGAHIKSLLTPEDITAIVSF-DDQYILMGTARGVVKKVKTSEFSNAKT--RGI---IAIKLDEGD
ELVSALLT---GGKDEVVLISRRGQALRTHE--VRPMRGHGVTGMKLA---ELTGLLKVSEDEKMLILSEYGFGKRVDFSEFSSHGRGTGGQKIY--GTG
E-IVGCVGVRDKEEIMCITSQGKSIKLKVASIRVMGRSAQGVKILSIDK-P-DFVSGLDRIV--------------------------------------
------------
>tr|A0A0R2VDX3|A0A0R2VDX3_9GAMM DNA gyrase subunit A OS=SAR86 cluster bacterium BACL1 MAG-121004-bin11 GN=ABS12_02240 PE=4 SV=1
-------HSQLLCFTTKGKVFWLKVYEIPVATRTSKGRPLVNMLKAETVTQILPVDEEKYIFMATKNGIIKKTNLNLFHKKYN--SGI---KAIRLDDDD
KLVGTVIT---NGDND-LLSSSSGKLIRFHESKVRPMRARGVKGISLKGK--VI-SLMIGDSKTILCLSENGYGKKTRLEDFPSYNRGGQGVIAL--SNG
N-MVSAVAVD-DDGIMLISDKGTLIRTAISQIPTLGRNTQGVKVITPKD-G-EKLIEGVRIP--------------------------------------
------------
>tr|J4UXA1|J4UXA1_9GAMM DNA gyrase subunit A OS=SAR86 cluster bacterium SAR86A GN=gyrA PE=3 SV=1
-------HVQILCFTTKGKVFWLKVYEIPVASRTSKGRPLVNMLNDERVSEILPVEDDKFIFMATRKGITKKTNLSLFARKWK--SGI---KAINLDEDD
RLVGTAIT---DGKKE-LLASSAGKLIRFNETKVRAMRARGVKGMKLKDR--LI-SLNVADEKTVLCVSENGYGKKTNLDDFPTHNRGGQGVISI--SNG
M-MVAATLVN-EDGIMLISDKGTMIRTNVSQVPTLSRNTQGVKIITPKE-N-EKLTECVTIP--------------------------------------
------------
>tr|J4X573|J4X573_9GAMM DNA gyrase subunit A OS=SAR86 cluster bacterium SAR86B GN=gyrA PE=3 SV=1
-------HDQILCFTTKGKVFWLKVYEIPVASRTSKGRPLVNMLKDERVSDILPVNDEQYIYMATKKGTNKKSNLSFFAKKYK--SGI---KAINLDDDD
RLIGTAIT---NGQDE-LLASSSGKLIRFHESKVRPMRARGVRGMKLKGS--LI-SLMVADTKTVLCVSENGYGKKTKLDDFPTHNRGGQGVISI--SNG
L-MVSAKLVE-DDGIMLISDKGTMIRTNVNQVPTLSRNTQGVKIISPKD-G-EKLIECVNIP--------------------------------------
------------
>tr|U2W7Y2|U2W7Y2_9FIRM DNA gyrase subunit A OS=Oribacterium sp. oral taxon 078 str. F0263 GN=gyrA PE=3 SV=1
-------HHYIMLFTNKGRCFRIKGYEIPES-RTSRGTALVNLLKPERVNACFSLRSEQYLVLATKSGLVKKTPLSQYANVRK--NGL---IAMNIREDD
QLIEAKLV---DPGEEIMLVTKKGMAIRFR---IRSTRAMGVRGIRLD---ELIGMQKL--GSHLLLVSEKGYGKLTATEEFKPQNRGGKGLHCYRITTG
D-LVGFKLCD-DREIMLITSEGILIRMSLGKVSV-GRNTSGVKFMDLPKNG-DTVIASIAKV--------------------------------------
------------
>tr|K8E1D5|K8E1D5_CARML DNA gyrase subunit A OS=Carnobacterium maltaromaticum LMA28 GN=gyrA PE=3 SV=1
-------HDTLLFFTNNGKVYRAKGYEIPEYGRTAKGIPAINLLGDEKIQAIINVKDNHFLFFTTLKGVVKRTSVSAFAN-RS--NGL---KSIVLREDD
ELMNVC-T---DG-QNVIIGTHLGYAVTFNE--VRDMRASGVRGIRLR---DVVGMDVMKPDSEVLVITENGYGKRTKASEYPIKGRGGKGIKTANITNG
N-LAGLTTVNE-EDIMLITNTGVIIRFDVDTVSQTGRATLGVRLIRVGED--AIVSTMAKVD--------------------------------------
------------
>tr|A0A0F2NQI4|A0A0F2NQI4_9FLAO DNA gyrase subunit A OS=Flavobacteriales bacterium BRH_c54 GN=gyrA PE=3 SV=1
-------HNYLLVFTEKGKCYWMRVFEIPEGTKQSKGRAIQNLINTDKVLAYINVKNNNFIIMCTEKGVVKKTTLEAYSR-RV--NGI---NAITVREGD
RLLEAKLT---SGSDEILLALKSGKAIRFN---TRPMRASGVRGIRLAE--DVIGMIAINDSRNILVVSENGYGKRSELE-YRVTNRGGKGVKTINITTG
G-LIAMKDVS-NDDLMIINKSGLVIRLAVETLRVMGRATQGVRLINLKG-N-DSIAAVAKVE--------------------------------------
------------
>tr|A0A0P7Z831|A0A0P7Z831_9BACT DNA gyrase subunit GyrA OS=Bacteroidetes bacterium HLUCCA01 GN=gyrA PE=4 SV=1
-------HNYILFFTEKGKCYWLKVYEIPEGTRLSRGRAIVNLIQKDHVKTFVPVKKNHFIMMGTKKGIVKKTSLEAYSR-RR--DGI---IAINIDDGD
HLLEAR-T---DG-STIILGAKNGRAIRFQE--VRDMRTRGVRGINLD--SDMVDMVVVKNEATVLAISENGYGKRSQVQDYREQSRGGKGVITMKITTG
N-LIALKEVSH-DDLMVITKKGKIIRMHCKDIRSMGRNTQGVRIIRLTS-D-DKIGGVTRVV--------------------------------------
------------
>tr|R5BCL4|R5BCL4_9BACE DNA gyrase subunit A OS=Bacteroides sp. CAG:927 GN=gyrA PE=3 SV=1
-------HSYMLFFTQKGRCYWLKVYEIPESAKNTKGRAVQNLLNADAINAIICVKENHNLVFATKNGVIKKTKLEAYSR-RA--AGV---NAIVIRDDD
QLISVEMT---DGNSEILLANRNGRAIRFP---VREMRSTGVRGMTLDP--DVVGMICMNPPDTVMVVSENGYGKRSVLDDYRITNRGGKGVKTLNITTG
K-LVAIKSVN-ENDLVIINKSGITLRVKMSDIRIQGRATQGVKIINLEKRN-DTIASVCCVD--------------------------------------
------------
>tr|A0A087ER46|A0A087ER46_9LACO DNA gyrase subunit A OS=Lactobacillus kunkeei GN=gyrA PE=3 SV=1
-------HHSLLFFTNLGKVYRMKGYEIPEYGRSAKGIPIINLLGDEKIQAVIPVDDGRFLFFTTLKGTVKRTPIDEFQN-RS--NGL---KAIHLKDED
ELMRVS-V---SE-QNIIIGTHLGYCVSFKV--VRSMRATGVRGIRLR---NVVGGDVLDPNDNVFVISENGYGKQTPASEYQIKGRGGKGIKTVKVTNG
P-LAGLTTVAD-EDIMLVTDKGVMIRFSISDVSQTGRATLGVHLIKIDED--SRVSTVARVQ--------------------------------------
------------
>tr|A0A0R2ASB9|A0A0R2ASB9_9LACO DNA gyrase, A subunit OS=Lactobacillus ozensis DSM 23829 = JCM 17196 GN=FD06_GL001055 PE=4 SV=1
-------HHNLLFFTNTGKVYSMKGYEIPEYGRSAKGIPIINLLGEETIQAVITISDDKFLFFTTLHGTVKRTPVEEFSN-RN--NGL---KAIHLKDND
ELIRVS-V---SE-DNMILGTHAGYSASFKV--VRSMRATGVRGIRLR---DVIGAAMLNPSDNVFVISEKGYGKQTAATEYAIKKRGGKGIKTVNVTNG
P-LAGLTTVSK-EDIMLVTDKGVIIRFNIDDVSQTGRATLGVHLIKIADD--SKVSTMAKVI--------------------------------------
------------
>tr|A0A090BWM5|A0A090BWM5_9ENTR DNA gyrase subunit A OS=Candidatus Tachikawaea gelatinosa GN=gyrA PE=3 SV=1
-------HDTILCFSNRGRLYSMKVHQLPEANRYSRGRPIVNLLP-ERITAILPINEEINIFMASAKGTVKKTAISELIRSRN--AGI---IAVNLREDD
ELIGVAFT---KGTNTILLFSSTGKVVCFNESSVRTMRASGVRGIKLA--KDVVSLIVSNEPGTILTVTKKGYGKRTEINKYPIKSRGTRGVISIKVTSG
P-VISAIQVFENDQIMIITDTGKLVRIRVSEVSTLGRNTQGVILIRTL-KE-ESVVGLQRVV--------------------------------------
------------
>tr|I3C143|I3C143_9FLAO DNA gyrase subunit A OS=Joostella marina DSM 19592 GN=gyrA PE=3 SV=1
-------HQYMLFFTQKGKCFWMRVYEIPEGSKTSKGRAIQNLINQDKVKAFICTKNSHFVIMATKKGVVKKTSLEQYSR-RQ--NGI---NAITVRDGD
ELLEAKLT---TGNSQILLAVKSGKAIRFE---TRPMRASGVRGITLADN-DVVGMVSVHNEENILVVSEKGYGKRTYLDVYRITNRGGKGVKTMSITTG
A-LVAIKNVS-EDDLMIITKSGVAIRMAIEDLRVMGRATQGVKLINLKN---DSIAAVAKVM--------------------------------------
------------
>tr|A0A068DRZ5|A0A068DRZ5_9BACT DNA gyrase subunit A OS=endosymbiont of Llaveia axin axin GN=gyrA PE=3 SV=1
-------HQYTLFFTKKGKCFWLRVYEIPEGSKTSKGRAIQNLIRPDRICAYILSGKNRYVIMVTESGIIKKTPIKKYSR-RR--NGI---NAITIREKD
TLLEAELT---TGNSEVLIAVKSGKAIRFS---VRPMRACGVKGIRMSE--DVIGMVCVKP--DILVVSEKGYGKRSFLE-YSITNRGGKGVKTINITTG
K-LISITSVY-TSDLMIITKDGITIRISVSDIRISGRSTQGVRLINLRE-G-DEIAAVAKVG--------------------------------------
------------
>tr|C0BH88|C0BH88_FLABM DNA gyrase subunit A OS=Flavobacteria bacterium (strain MS024-2A) GN=gyrA PE=3 SV=1
-------HQYMLFFTQKGKCFWMRVYEIPEGSKTAKGRAIQNLINQDKVQAFICTQNNHYVIMATKKGQVKKTSLEQYSR-RA--NGI---NAINVREDD
ELLEAKLT---NGNSHVMLAVKSGKAIRFE---TRPMRASGVRGITLAS--DVVGMVAVNDDANILVVSENGYGKRSSLD-YRITNRGGKGVKTISITTG
K-LVTIKTVT-TDDLMIINKSGIAIRMEVAALRVMGRATQGVRLINLKG-D-DTIAAVAKVM--------------------------------------
------------
>tr|A0A0R2VNY1|A0A0R2VNY1_9SPHI DNA gyrase subunit A OS=Sphingobacteriales bacterium BACL12 MAG-120813-bin55 GN=ABR95_09655 PE=4 SV=1
-------HDTMLFFTKMGKCFWLPVYQIPEGSRTSKGRAIQNMISPDKVMAFIDVRNNHFVVFCTRKGVIKKTALEAFSR-RT--NGI---AAISINEGD
ELLEVKMT---DGNCEVMLAVRSGRAIRFP---VRPMRAAGVRGVLLES--DVVGMISVEKESTILVVSENGYGKRSYITVYRITNRGGKGVNTIKVTTG
A-LIAIKSVT-NDDLMIMTEKGIAIRMSVNDIRVMGRATQGVRLINLKD-N-DRIASVAKAE--------------------------------------
------------
>tr|F9YQ65|F9YQ65_CAPCC DNA gyrase subunit A OS=Capnocytophaga canimorsus (strain 5) GN=gyrA PE=3 SV=1
-------HQYMLFFTQKGKCFWMRVYEIPEGSKTSKGRAIQNLINQDKVKAFISVQNSNYLIMATKQGIVKKTLLEQYSR-RQ--NGI---NAITIKEGD
ELLEAKLT---SGKSQLMLAVKSGRAIRFG---VRAVRSQGVRGIDLDEN-DVIGMIAIENEETVLVVSENGYGKRSYIDVYRITNRGGKGVKTISITTG
N-LVAIKSVL-GEDLMIINKSGIAIRLPIDDLRIMGRATQGVRLINIKG-K-DSIAAVAKVM--------------------------------------
------------
>tr|A0A0Q9ZAW7|A0A0Q9ZAW7_9FLAO DNA gyrase subunit A OS=Salegentibacter mishustinae GN=APR42_04880 PE=4 SV=1
-------HQYMLFFTQKGKCFWMRVYEIPEGSKASKGRAIQNLINPDRVKAFICTQNKHYVIMATKKGQVKKTSLEQYSR-RT--NGI---NAITIKEDD
ELLEAKLT---NGDSQVMLAVRSGKAIRFE---TRPMRASGVRGITLAD--DVVGMISVEDNSDILVVSENGYGKRSSLE-YRITNRGGKGVKTISITTG
S-LVAIKNVS-DEDIMIINKSGIVIRMEVSNLRVMGRATQGVRLINLKG-N-DAIAAVAKVL--------------------------------------
------------
>tr|A0M1I2|A0M1I2_GRAFK DNA gyrase subunit A OS=Gramella forsetii (strain KT0803) GN=gyrA PE=3 SV=1
-------HQYMLFFTQNGKCYWMRVYEIPEGSKASKGRAIQNLINPDKVNAFICTQNDHFVIMATKKGQVKKTRLEKYSR-RT--NGI---NAITIKEGD
ELLEAKLT---TGNSQVMLGLRSGKAIRFE---TRPMRASGVRGITLAD--DVVGMIAVNDESDILVVSENGYGKRSSLE-YRITNRGGKGVKTISVTTG
Q-LVAIKNVS-IDDLMIINKSGIVIRMAVEDLRVMGRATQGVRLINLKG-N-DAIAAVAKVL--------------------------------------
------------
>tr|H2BYK6|H2BYK6_9FLAO DNA gyrase subunit A OS=Gillisia limnaea DSM 15749 GN=gyrA PE=3 SV=1
-------HQYMIFFTQNGKCYWMRVYEIPEGSKTSKGRAIQNLINPDKVKAFICTQNSHYVIMATKKGQVKKTSLEQYSR-RV--NGI---NAITIREDD
ELIEAKLT---NGESQVMLALKSGKAIRFE---TRPMRASGVRGITLAD--DVVGMIAVNDEANVLVVSENGYGKRSKLE-YRITNRGGKGVKTISVTTG
E-LVTIKNVT-KDDLMIINKSGLAIRMSIENLRVMGRATQGVKLINLKG-N-DAIAAVAKVM--------------------------------------
------------
>tr|A3XM11|A3XM11_LEEBM DNA gyrase subunit A OS=Leeuwenhoekiella blandensis (strain CECT 7118 / CCUG 51940 / MED217) GN=gyrA PE=3 SV=1
-------HQYLIFFTEKGKCFWVRVFEIPEGSKTSKGRAIQNLINPDKVKAFICTNNSHYVIMATKKGQVKKTSLEQYSR-RT--NGI---NAITIKEGD
ELLAAKLT---TGDSQVMLAVKSGKAIRFE---TRPMRASGVRGITLAD--DVIGMVAVNDESNVLVVSENGYGKRSLVE-YRVTNRGGKGVKTISVTTG
N-LVAINNVT-EDDLMIINKSGIAIRMEVSELRVMGRATQGVRLINLKK-G-DTIAAVTKVK--------------------------------------
------------
>tr|A0A0D6TJS3|A0A0D6TJS3_9FLAO DNA gyrase subunit A OS=Flavobacterium sp. 316 GN=gyrA PE=3 SV=1
-------HQYLMYFTQKGKCYWMRVFEIPEGTKASKGRAIQNLINKDKVKAFICTKNSHYVIMATKQGQVKKTSLEQYSR-RQ--NGI---NAITIKEDD
ELLEAKLT---TGNSHVLLAVKSGKLVRFE---TRPMRASGVRGITLAE--DVIGMVSIDEDSQILVVTENGYGKRTKL-VYRVTNRGGKGVKTLNLTTG
A-LIAINAVT-EDDLMIINKSGLTIRMEISDLRVMGRATQGVRLINIKG-K-DSIAAVTKVL--------------------------------------
------------
>tr|A3U9V0|A3U9V0_CROAH DNA gyrase subunit A OS=Croceibacter atlanticus (strain ATCC BAA-628 / HTCC2559 / KCTC 12090) GN=gyrA PE=3 SV=1
-------HQYMIFFTQKGRCFWMRVFEIPEGSKTSKGRAIQNLINPDKVKAFICTQNSHYVIMATKKGQVKKTSLEQYSR-RI--NGI---NAITIKEDD
ELLEAKLT---TGDSEIMLAVKSGKCIRFE---TRPMRASGVRGIRLAEK-DVVGMVVVNNDSDILVVSENGYGKRSSLE-YRMTNRGGKGVKTISVTTG
E-LVAIKNVT-DDDLMIINKSGIAIRLSVENLRVMGRATQGVRLINLKG-D-DAIAAVAKVK--------------------------------------
------------
>tr|A9E3P5|A9E3P5_9FLAO DNA gyrase subunit A OS=Kordia algicida OT-1 GN=gyrA PE=3 SV=1
-------HQYMLFFTQQGKCFWMRVYEIPEGSKTSKGRAIQNLINKDKVKAFICTQNNHYVIMATKKGQVKKTPLEQYSR-RT--NGI---NAITIKDGD
ELLEAKLT---TGNSQVMLAVKSGKAIRFE---TRPMRASGVRGIRLAD--DVVGMVAVNDESNILVVSENGYGKRSSLE-YRITNRGGKGVKTISVTTG
Q-LVAIKNVT-EDGLMIINKSGIAIRMAVADLRVMGRATQGVRLINIKG-K-DSIAAVAKVR--------------------------------------
------------
>tr|A0A0A3I521|A0A0A3I521_9BACI DNA gyrase subunit A OS=Lysinibacillus manganicus DSM 26584 GN=gyrA PE=3 SV=1
-------HDAILFFTSKGKVYLTKGYEIPEYSRTAKGLPIVNLLNKEKVTAMIRSEEDAYFIFTTKMGITKRTPLSQFAN-RK--NGL---IAVGLHDED
ELISVR-T---DG-KDIIIGTNDGMLIRFKE--IRSMRAAGVRGIKLR--DDVVGMEIIEPGQEILVVTEKGYGKRTPESEYRLQNRGGVGIKTIQITNG
P-MCAVKTVDT-EDIMIITINGIIIRMDVNDISVIGRSTQGVRLIRLGE-D-ELVATVARVK--------------------------------------
------------
>tr|F2F249|F2F249_SOLSS DNA gyrase subunit A OS=Solibacillus silvestris (strain StLB046) GN=gyrA PE=3 SV=1
-------HDTILFFTSKGKVFRAKGYEIPEFGRQAKGLPIVNLLNKEHVTAMIRVTEDAYFIFTTKTGVTKRTPVDQFAN-RT--NGL---IAITLREDD
DLISVH-T---DG-KEIIIGTSDGMLVRFKE--IRSMRAAGVRGIKLR--GDVVGMEILEPGQEILVVTENGYGKRTPESEYRLQSRGGLGLKTMQITNG
K-MCAVKAVDS-EDIMLITINGMLIRMDVNDISVIGRSTQGVRLIRLAE-G-EYVATVARVK--------------------------------------
------------
>tr|A0A0A3HS91|A0A0A3HS91_9BACI DNA gyrase subunit A OS=Lysinibacillus sinduriensis BLB-1 = JCM 15800 GN=gyrA PE=3 SV=1
-------HDTILFFTTKGKVYRAKGYEIPEFGRTAKGLPIVNLLNKEKVTAMIRVDEDAYLIFTTKTGITKRTQLSQFAH-RT--SGL---IAINLHDDD
DLISVR-T---DG-KDVIIGTHDGMLIRFKE--IRSMRASGVRGIKLR--GDVVGMEIIEPGHEILVVTERGYGKRTPESEYRLQSRGGVGLKTIQITNG
P-MCAVKTVDT-EDIMLITINGILIRMDVNDISVIGRSTQGVRLIRLGN-E-ELVATVARVK--------------------------------------
------------
>tr|A0A0C2SGW4|A0A0C2SGW4_9BACL DNA gyrase subunit A OS=Jeotgalibacillus campisalis GN=gyrA PE=3 SV=1
-------HDTILFFSNKGKVYRTKGYEIPEYSRTAKGLPIINLLGKEDINAMIRVEEDSFFFFTTKYGISKRTPVSDFAN-RT--NGL---IAINLREGD
DLISVK-T---DG-KEIIIGTQNGLLIRFPE--VRSMRATGVRGIRLK--EDVVGMEILEPDNEILVVTENGYGKRTTEKDYRVQSRGGKGIKTCNITNG
K-LIAVKTVTD-EDVMIITVNGVLIRMDVSGISQTGRSTQGVKLIRLGD-Q-EYVATVTRIE--------------------------------------
------------
>tr|A0A0C2VEC5|A0A0C2VEC5_9BACL DNA gyrase subunit A OS=Jeotgalibacillus alimentarius GN=gyrA PE=3 SV=1
-------HDTILFFTNKGKVYRAKGYEIPEFSRTAKGLPLVNLLEKEVVNAMIRVEEKSYFFFTTKRGISKRTPATDFAN-RN--NGL---IAINLRDDD
ELISVK-T---DG-REIIIGTKNGLMIRFPE--VRSMRAGGVRGIRLN--DDVVGMEILGEGNDILVVTEKGYGKRTPEEEYRVQSRGGKGIKTCNITNG
R-LVAVKAVTE-EDIMLITAHGVLIRMDVSGISQTGRSTQGVKLIRLGD-E-EHVATVTRIE--------------------------------------
------------
>tr|A0A0C2RG65|A0A0C2RG65_9BACL DNA gyrase subunit A OS=Jeotgalibacillus soli Cunha et al. 2012 GN=gyrA PE=3 SV=1
-------HDTILFFTNKGKVYRTKGYEIPEYSRTAKGLPIINLLEKEVINAMIRVEEDSFFFFTTRYGVSKRTPVSDFAN-RT--NGL---IAINLKEGD
ELISVK-T---NG-KEIIVGTKNGMLIRFPE--VRSMRATGVRGINLN--DDVVGMEILEPGNNILVVTEKGYGKQTPEEDYRVQSRGGKGIKTCNITNG
K-LVSVKAVTQ-EDLMLITGQGVLIRMDVSDISQTGRNTQGVKLIRLGD-Q-EYVATVTRIE--------------------------------------
------------
>tr|A9KCT7|A9KCT7_COXBN DNA gyrase subunit A OS=Coxiella burnetii (strain Dugway 5J108-111) GN=gyrA PE=3 SV=2
-------HDTILCFSTQGKVYWLKVYQVPQGSRIARGRPIINLLPKEQISAILPIR-SHFVFMATAQGAIKKVSLAEFSQPRT--KGK---IALALNEGD
RLVGVDIT---DGKKEIMLVTDAGKAIRFHEKEVREMRARGVRGIKLKAQN-VIALIVVKPKGNILTATVHGYGQRTALDDYRSTGRGGQGVMAIRINNG
K-VVSAAQVFDDDDVLLISDKGTLVRTRVNEISQMGRNTQGVRLIQLS-QD-ELLVGMEAIS--------------------------------------
------------
>tr|A0A0H4UTN6|A0A0H4UTN6_9COXI DNA gyrase subunit A OS=Coxiella-like endosymbiont GN=gyrA PE=3 SV=1
-------HDTILCFSTYGKVYWLKVYQVPQGGRTSRGRPVVNLLP-EHISTILSIRKSHFVFMTTAQGSVKKVTLAEFSQPRT--NGK---IALALKEGD
RLVGVDIT---DGNKEVMLVTDVGKAIRFHENEVREMRARGVRGIKLKE--QVIALIIVKPGGYILTTTIHGYGQRTTIEDYRPTGRGGQGVIAIRVNNG
N-VVSAAQVFDNDEVLLISDKGTLVRIRVNEISQMGRNTQGVRLIQLA-QE-ESLVGMEAIS--------------------------------------
------------
>tr|A0A0A8EAP0|A0A0A8EAP0_9COXI DNA gyrase subunit A OS=Coxiella endosymbiont of Amblyomma americanum GN=gyrA PE=3 SV=1
-------HDTILCFSTYGKVYWLKVYQVPQSSRVSYGRPVVNLLP-EYISAILPIRKSHFIFMTTAKGSVKKVVSSEFFQSRM--NGK---IALTLKTED
RLVGVDIT---DGNKEVMLITDAGKAIRFHESEVRAMRAHGVCGIKLKE--QVISLIIVKPGGYILTATSHGYGQRTAIESYRSTSRGGQGVIAIRINNG
N-VVSATQVFNNYEVLLISNKGTLVRIRVNEVSQMGRNTQGVRLIQLA-QE-EILVGMEAIS--------------------------------------
------------
>tr|K2BTV6|K2BTV6_9BACT DNA gyrase subunit A OS=uncultured bacterium (gcode 4) GN=gyrA PE=3 SV=1
-------HHTILCFSTMGKAYWLKTYQVPQGGRVARGQPIVNLLP-ELITAILPVAENHFIFMATQNGTVKKVALTEFENARS--NGK---IALSLNEGD
RLIGVALT---DGKQDIMLVSDAGKAIRFSEEAVRAMRATGIRGIKLKN--QLIALIIPKKDGTILTVTENGYGQRTEVNDYRECGRGGQGVIAIQTTNG
R-VVGSIPVQQDSEILLVTNGGTLVRIPVAEINVIGRNTQGVRLINVQ-EG-EKVVSVEGVD--------------------------------------
------------
>tr|A0A059NVW3|A0A059NVW3_9BACI DNA gyrase subunit A OS=Halobacillus karajensis GN=gyrA PE=3 SV=1
-------HNTLLFFSNKGKVYKAKGYEVPEFNRTAKGIPIINMLNREWINAVIAVEDDWYLVFTTRNGITKRTTLSQFAN-RK--GGL---IALGLREDD
ELISVR-T---DG-KDVMIGTQNGYLIRFNE--IRAMRAAGVKGISLR--DDVVSMEILDDSLQVLTVTSKGYGKRTPADEYRITNRGGKGIITCNLTNG
H-VVATKAVNE-EDIMIITASGVLIRMPMESISETGRNTQGVRLIRLGE-G-EEVATVARVE--------------------------------------
------------
>tr|A0A0A2TGJ6|A0A0A2TGJ6_9BACI DNA gyrase subunit A OS=Pontibacillus yanchengensis Y32 GN=gyrA PE=3 SV=1
-------HNTLLFFTNKGKVYRAKGYEVPEFSRTAKGIPIINLLEKEWVNAVIAVEDDWYLFFTTKHGISKRTTLSQFAN-RR--GGL---IALGLREDD
ELISVR-T---DG-KHIMIGTKGGYVIRFPE--VRTMRAAGVKGISLR--GDVVSMEMIEDGLQVLNVTTKGFGKRTPANEYRITGRGGKGIRSCNLTNG
E-VVTVKSVTD-EDIMIITESGVLIRMPVESISQTGRNTQGVRLIRLQD-D-EEVATVAQIE--------------------------------------
------------
>tr|A0A0A5ICU4|A0A0A5ICU4_9BACI DNA gyrase subunit A OS=Pontibacillus halophilus JSM 076056 = DSM 19796 GN=gyrA PE=3 SV=1
-------HHTLLFFTNKGKVYRAKGYEVPEFSRTAKGIPIINLLGKEWVNAVIAVDEESYLFFTTKFGVSKRTSVSQFAN-RK--GGL---IALNLREGD
ELISAR-T---DG-KDIIIGTKGGYLIRFPE--VRPMRASGVKGISLR--DDVVSMEILEEDVYVLNVTTKGFGKRTPASEYRITGRGGKGILTCNLTNG
E-VVTVKAVRE-EDVMIITESGVLIRMPVDSISITGRNTQGVRLIRVQD-E-EEVATVARIA--------------------------------------
------------
>tr|A0A0M9GSI6|A0A0M9GSI6_9BACI DNA gyrase subunit A OS=Bacillus sp. CHD6a GN=gyrA PE=3 SV=1
-------HDTLLFFTNKGKVYRAKGYEIPEFSRTAKGIPIINLLEKEWVNAIIPVEDDWYLFFTTKHGISKRSPLSQFAN-RK--GGL---IALGLRESD
ELISVK-T---DG-KEMIIGTKNGMLIRFHE--VRSMRATGVKGISIA--NDVVGMELLDEGLDVLVVTKNGYGKRTPAEEYRVQSRGGKGIKTCNITNG
E-LVSVKTVTE-EDLMLITASGVLIRMSVDGISQMGRNTQGVKLIRLAE-N-EFVTTVARVD--------------------------------------
------------
>tr|I3E0W8|I3E0W8_BACMT DNA gyrase subunit A OS=Bacillus methanolicus PB1 GN=gyrA PE=3 SV=1
-------HDTILFFTNKGKVYRAKGYEIPEFSRTAKGIPIVNLLEKEWINAIIPVEENWYLFFTTKEGISKRSPLSSFAH-RN--NGL---IALNLREGD
ELISVR-T---DG-KHIIIGTKNGMLIRFPE--VRSMRATGVKGISLD--GDVIGMEVLEENNDILIVTKNGYGKRTPASEYRVQGRGGKGIKTCNITSG
N-LVAMKAVTE-EDLMLITAGGVLIRIDVGGISVMGRNTQGVKLIRLEADN-EYVATVAKVE--------------------------------------
------------
>tr|A0A0J1I2D2|A0A0J1I2D2_BACCI DNA gyrase subunit A OS=Bacillus circulans GN=gyrA PE=3 SV=1
-------HDTILFFTNKGKVYRLKGYEIPEFSRTAKGIPIINLLGKEWVNAIIPVSDDWYLFFTTKEGISKRSPLSSFAN-RN--NGL---IAVNLRDGD
ELISVR-T---DG-KEIIIGTKNGLLIRFPE--VRSMRATGVKGITLS--EDVVGMEVLEENSEILIVTKKGYGKRTPIDEYRVQGRGGKGIKTCNITNG
N-LVSMKVVTE-EDVMIITTGGVLIRMAVSDISTMGRSTQGVRLIKLNESN-EFVATVAKVE--------------------------------------
------------
>tr|A0A0J5UM49|A0A0J5UM49_9BACI DNA gyrase subunit A OS=Bacillus aryabhattai GN=gyrA PE=3 SV=1
-------HDTILFFTNKGKVYRTKGYEIPEYGRTAKGIPIINLLEKEWVNAIIRVDDDWYLFFTTKQGISKRTPLSSFEN-RN--SGL---IALNLREED
ELISVK-T---DG-RDMVIGTKKGMLIRFNE--VRSMRATGVKGITLD--EDVIGMEILEEQSDILIITKNGYGKRTPIEEYRVQTRGGKGLRTCNITNG
D-VVALKCVSE-EDIMLITVSGVLIRVSVSDISQMGRNTQGVKVIRLGD-E-EFVSTVAKVQ--------------------------------------
------------
>tr|A0A0A5HPW4|A0A0A5HPW4_9BACI DNA gyrase subunit A OS=Pontibacillus litoralis JSM 072002 GN=gyrA PE=3 SV=1
-------HNTILFFTNKGKVYRAKGYEIPEFSRTAKGLPIINLLEKEWVNAVIPVEDDWYLFFTTKNGISKRTTLSQFAN-RR--GGL---IALTLKEED
ELISVR-T---DG-KHIMIGTKGGYLIRFPE--VRTMRAAGVKGISLR--ADVVSMEIIEDGLQVLNVTTKGFGKRTPAEDYRITGRGGKGVLTCNLTNG
D-VVAVKSVSD-EDIMIMTEDGVLIRMSVESVSQTGRNTQGVKLISLKD-G-AEVATVARIA--------------------------------------
------------
>tr|A0A0Q3SIA5|A0A0Q3SIA5_9BACI DNA gyrase subunit A OS=Bacillus sp. FJAT-25509 GN=AN960_03850 PE=4 SV=1
-------HDTILFFTNKGKVYRSKGYEIPEFSRTAKGLPIVNLLERENINAIIPVSEDWYLFFTTKQGIAKRVPLSAFAN-RT--NGL---IAINLKEDD
DVISVR-T---DG-KDIVVGTSKGMMIRFNE--VRSMRATGVKAITLS--DDVVGMEVVEEHLDILVVTELGYGKRTAQEEYRIQSRGGKGLKTLNVTNG
K-MISLKCVSE-QDLMLITESGVIIRMPIEQISRLGRVTQGVKLIKLDQ-E-GHVATVAIAA--------------------------------------
------------
>tr|A0A075LLN1|A0A075LLN1_9BACI DNA gyrase subunit A OS=Terribacillus aidingensis GN=gyrA PE=3 SV=1
-------HDTILFFTNKGKVYRAKGYEVPEFSRTAKGIPIINMLEKEWINALIPVKDDWYLIFTTKQGVSKRTTLSQFAN-RK--GGL---IALNLREDD
ELISVR-T---DG-KHIMIATKNGYLIRFPE--IRPMRAAGVKGITLR--DDVVSMDIIDEGVDILNVTEKGFGKRTPESEYRITNRGGKGILTSKITTG
Q-MVSAKPVTE-EDIMIITVSGVLIRMPVSSISSTGRNTQGVILIRIQE-N-EAVATVARID--------------------------------------
------------
>tr|A0A084GNE7|A0A084GNE7_9BACI DNA gyrase subunit A OS=Bacillus cibi GN=gyrA PE=3 SV=1
-------HDTILFFTNKGKVYRTKGYEIPEYGRTAKGLPIINLLEKEWVNAIIPVSDDWSLFFTTKEGISKRSPLSQFAN-RK--GGL---IAVNLREAD
ELISVR-T---DG-KHIMIGTKKGMLIRFPE--VRSMRATGVKGITLD--DDVVGMEILEEDADVLTVTRNGFGKRTPAAEYRVQSRGGKGIKTCNVTNG
T-VISVKPSTE-EDLMLITASGVLIRMAIDSISTTGRNTQGVKLIKLGG-E-EHVATVAVVE--------------------------------------
------------
>tr|A0A0K9GHR1|A0A0K9GHR1_9BACI DNA gyrase subunit A OS=Bacillus sp. FJAT-27916 GN=gyrA PE=3 SV=1
-------HDTILFFTNKGKVYRSKGYEIPEFGRTAKGLPIINLLEQEWVNAIIPVQDDWFLFFTTKQGISKRSPLSSFSN-RN--NGL---IALGLREND
ELISVK-T---DG-RDIIIGTKNGLLIRFPE--VRSMRATGVKGISLS--GDVVGMDILEEKDDILIVTKKGYGKRTGEEEYRIQSRGGKGIKTCNVSNG
E-LVSVQTVT--EDLMVITANGVIIRMDVGQISRLGRNTMGVKLIRLEDGD-QYVSTVAKVE--------------------------------------
------------
>tr|Q2B0I1|Q2B0I1_9BACI DNA gyrase subunit A OS=Bacillus sp. NRRL B-14911 GN=gyrA PE=3 SV=1
-------HNTLLFFTNKGKVYRAKGYEIPEFSRTAKGIPIINLLGKEWVNAVIPVEDEWFLFFTTKEGISKRSPLTSFGN-RN--NGL---IALNLREGD
ELISVR-T---DG-KEIIIGTKNGQLIRFPE--VRSMRATGVKGITLD--DDVVGMEVLEENSEILMVTKKGYGKRTPEMEYRVQGRGGKGIKTGNITNG
T-IVAVKVVTE-EDIMLITTGGVLIRMAVGDISTMGRNTQGVRLIRINDSG-EYVATVAKVE--------------------------------------
------------
>tr|A0A0M6W9L9|A0A0M6W9L9_9FIRM DNA gyrase subunit A OS=Eubacterium rectale GN=gyrA PE=3 SV=1
-------HHYLMFFTNTGRVYRIKAYEIPEASRTSRGTAIINLIPPEKITAMIPIKDDKYLFMATRNGIVKKTPIKDYEN-RK--NGL---AAINLREDD
KLIEVK-T---DN-EDILLFTKFGQCIRFKE--VRSTRTMGVIGMNLA---NIIAMQTASMGEAVLLVSSNGLGKRTRIDEFTTQNRGGKGVKCYKITSG
N-LVGVKSVED-DELMLITTEGIIIRIQVSDVTVLGRITTGVKLINLKE-G-VSVASIAKVV--------------------------------------
------------
>tr|A0A0M6WLK8|A0A0M6WLK8_9FIRM DNA gyrase subunit A OS=Roseburia faecis GN=gyrA PE=3 SV=1
-------HHYLMFFTNMGRVYRIKAYEIPEASRTSRGTAIINIIPPEKITAMIPIKKDKYLFMATKNGIVKKTSVLDYEN-RK--TGL---AAISLRDDD
ELIEVK-T---GD-EEILLFTRYGQCIRFKE--VRATRTMGVIGMNLT---GVIAMQMASQGESVMIVSENGLGKCTRINEFTTQNRGGKGVKCYKITSG
N-LIGVKSVVD-DELMLITTEGIIIRIRVNDTALLGRVTSGVKLIDLKS-G-VTVASIARVV--------------------------------------
------------
>tr|R5YT06|R5YT06_9FIRM DNA gyrase subunit A OS=Roseburia sp. CAG:197 GN=gyrA PE=3 SV=1
-------HHYLMFFTNMGRVYRIKAYEIPEASRTSRGTAIVNLIPPEKITAMIPIKKDKYLFMATKNGIVKKTSVLDYEN-RK--TGL---AAINLRDDD
KLIEVK-T---DD-EDIFLFTKYGQCIRFNE--VRSTRTMGVIGMNLT---GVIAMQMASQGDSVLIVSEKGLGKCTLISEFSAQNRGGKGVKCYKITSG
N-LIGVKSVGD-DEVMLITTEGIIIRIRVNDTALLGRITSGVKLINLKD-D-ITVASIARVV--------------------------------------
------------
>tr|R5QHP5|R5QHP5_9FIRM DNA gyrase subunit A OS=Firmicutes bacterium CAG:194 GN=gyrA PE=3 SV=1
-------HYYIMFFTNFGRVYRMKGYEIPEAGRTARGTAIINLLQPEKVNAVIPIPTGKNLFMVTKNGIVKKTPIDEFDH-RK--NGL---AAINLRDDD
ELIEVK-T---DK-TEIFLVTKNGMCIRFKE--VRATRSMGVIGMNLT---QIIGMQLDHQGDSLLIVSEKGMGKRTYLDEFNVQKRGGKGVKCYKITTG
Y-VVGVKAVND-HEIMMITTEGIIIQLRMEDVSTLGRITSGVKMINLDEN--VKVAKIAKVR--------------------------------------
------------
>tr|A4BM47|A4BM47_9GAMM DNA gyrase subunit A OS=Nitrococcus mobilis Nb-231 GN=gyrA PE=3 SV=1
-------HDTLLCFSSHGKCYWLKVYELPHGSRGSRGKPIVNLLP-ERISAVVSIKDQHFVFMATRKGTVKKTPLSDFSRPRS--SGI---IAVNLQEDD
WLVNVGIT---DGEREIMLLTDAGKAIRFPEDAVRPMRAGGVRGIQLGTQS-VIQLLILG-EGDILTATENGYGKRTPVAEYPRRSRGGRGVISIQTSNG
N-VVGAAQVTEEDEIMLITNAGTLVRIPVAEISIVSRNTQGVKLIALG-GE-ERLAGVARIE--------------------------------------
------------
>tr|A0A0R1WP63|A0A0R1WP63_9LACO DNA gyrase subunit A OS=Lactobacillus hayakitensis DSM 18933 = JCM 14209 GN=FC40_GL001549 PE=4 SV=1
-------HDELLFFTNTGKVYRMKGYEIPEYGRTAKGIPMINLLDSEKIQTVINVPKEMYLFFITRQGVVKRTAVSEFGN-RK--NGL---KAVTLHEDD
ELINVL-T---DN-KNIIIATHQGYAVSFAE--IRSMRAAGVRGVRLR---NVVGSAILEADDQVFVISEKGYGKKTLASEYPIKGRGGKGIKTSNITNG
P-LAGMTTVTN-EDIMVITNKGVMIRFGADKVSQTGRATLGVRLINLDDD--SIVSTMTKVE--------------------------------------
------------
>tr|A0A0R2AIE4|A0A0R2AIE4_9LACO Dna gyrase subunit a OS=Lactobacillus agilis DSM 20509 GN=FC14_GL002000 PE=4 SV=1
-------HDELLFFTNLGKVYSMKGYEIPEYGRAAKGIPVINLLNEEKITTVINVPDDLALFFTTKLGVVKRTSVAEFTN-RK--NGL---KALNLHEGD
ELINVV-V---KA-ANVIIGTHQGYSVSFAV--VRLMRAAGVRGIRLR---AVVGSDVLAADSKVFVISEKGYGKQTLASEYPIKGRGGKGIKTANIGNG
P-LVGLTTVKD-EDIMVITDKGVMIRFNIETVSQTGRATMGVHLINLDED--SVVSTMAKVE--------------------------------------
------------
>tr|V7HVM0|V7HVM0_9LACO DNA gyrase subunit A OS=Lactobacillus equi DPC 6820 GN=gyrA PE=3 SV=1
-------HDMLLFFTNKGKVYSMKGYEIPEYGRTAKGIPVINLVEEEKISTVLNVTNKLRLFFTTKNGVVKQTSVADFTN-RK--NGL---KALTLRDND
ELINVS-L---DQ-STIIIGTHQGYAASFAS--VRVMRASGVRGIKLR---DVVGTGVLTSDSKVLVISENGYGKLTKASEYPVKGRGGKGVKTSTITNG
P-LVGFTTIND-EDIMVITDKGVMIRFDAQNVSEVGRSAMGVRLMNLRDG--GKVSTMTVVA--------------------------------------
------------
>tr|V6DMR4|V6DMR4_9LACO DNA gyrase subunit A OS=Lactobacillus salivarius cp400 GN=gyrA PE=3 SV=1
-------HDELLFFTNVGKVYRMKAYEIPEYGRTAKGIPVINLLDSEKIQTVINIPKEMYLFFITRQGTVKRTSVSEFGN-RK--NGL---KAITLRDGD
ELINVL-T---DD-KNIIIGTHQGYAVSFDE--IRSMRAAGVRGIRLR---NVIGSAILEPESKVFVISENGYGKQTAASEYPIKGRGGKGIKTTNITNG
P-LAGLTTVND-EDIMVITDKGVMIRFKISDVSETGRATLGVRLINLGAD--SIVSTMTKVE--------------------------------------
------------
>tr|F4XGH3|F4XGH3_9FIRM DNA gyrase subunit A OS=Ruminococcaceae bacterium D16 GN=gyrA PE=3 SV=1
-------HDYLFFFTDTGKVYRKKGYQIPEG-KTAKGTNIVNILQQEKVQTMIHTRPDLYLVMVTRNGTVKRLPVTALKNIRN--SGI---RALRLEEGD
QLISVRET---DGTKKILIATHDGMAVCFD---VRPMRAVGVRGIRLR---YVVSAARATAGRTVLTITEKGYGKRTPVEDYR-TNRGGIGIKNYAVTTG
K-IVGIKVVD-SEDLLLVTQAGILIRTHVDAIR-AGRATQGVIVMRFKE-E-GKVISLALAE--------------------------------------
------------
>tr|V2YII1|V2YII1_9FIRM DNA gyrase subunit A OS=Firmicutes bacterium ASF500 GN=gyrA PE=3 SV=1
-------HDYILFFTDTGKVYRKKGYQIPEG-KTAKGTNIINILQQERVQAMLHYREELYLFMVTRNGTVKRLPVQTLKNLRN--NGI---RALRLDEGD
QLVSVRET---DGSKKILIATHDGMAVCFD---VRPMRAVGVRGIRLR---YVVGAARALEGKTVLSITEKGFGKRTPVEEYR-TNRGGLGIKNYMVTTG
P-IVGVKVVD-SEDLLVVTQAGILIRTHVDAIK-CGRSTQGVIVMRFKE-E-GKVISLALAE--------------------------------------
------------
>tr|R5RZW4|R5RZW4_9FIRM DNA gyrase subunit A OS=Firmicutes bacterium CAG:129 GN=gyrA PE=3 SV=1
-------HDYILFFTDTGKVYRKKGYQIPE-GKAAKGTNIVNIIQTERVQAMLHFREKLYLTMVTRNGTVKRLPVETLKNLRS--NGI---RALSLDEGD
ELVAVRET---DGSQRILIATHDGMACVFD---VRAMRAVGVRGIRLR---YVVGTARA--GKQVLSITENGFGKKTPVEEYRITNRGGLGIKNYSVTTG
G-VVGVKVVD-SEDLLLVTRAGILIRTPVADIRS-GRATQGVIVMRFKEEG-DQVISMALAE--------------------------------------
------------
>tr|U2RZU8|U2RZU8_9FIRM DNA gyrase subunit A OS=Oscillibacter sp. KLE 1745 GN=gyrA PE=3 SV=1
-------HDYILFFTDTGKVYRKKGYQIPEG-KAAKGTNIVNILQQERIQAMIHTRDGRFLFMVTRNGTVKRLPANTLKNLRN--NGI---RALRMEEGD
QLIAVRET---DGSQKILIATHDGMAVCFD---VRPMRAVGVRGIRLR---YVVGAARAKANHAVLAITENGYGKQTPVEDYR-TNRGGLGIKNYMVTTG
P-VVGIKVVD-TEDLLLVTQAGILIRTPVDSIR-AGRATQGVIVMRFKE-E-GHVISLALTD--------------------------------------
------------
>tr|G4KQC3|G4KQC3_OSCVS DNA gyrase subunit A OS=Oscillibacter valericigenes (strain DSM 18026 / NBRC 101213 / Sjm18-20) GN=gyrA PE=3 SV=1
-------HDYILFFTDTGKVYRKKGYQILEG-KTAKGTNLINILQQERVQAMVHTRDGRFLFMVTRNGTVKRLPASTLKNLRN--NGI---RALRMDEGD
QLITVRET---DGTKKILIATHDGQAVCFQ---VRPMRAMGVRGIRLR---YVVAAARATEGKTVLSITEKGYGKRTPVEDYR-TNRGGLGIKNYMVTTG
P-VVGVKVVD-SEDLLLVTQSGIMIRTPVESIR-AGRATQGVIVMRFKE-D-GQVISMALTD--------------------------------------
------------
>tr|C5EQT6|C5EQT6_9FIRM DNA gyrase subunit A OS=Clostridiales bacterium 1_7_47FAA GN=gyrA PE=3 SV=1
-------HHFMMFFTNKGRVYRLKAYEIPEAGRTARGTAIINLLQPEKITAIIPMREDKYLFMATRNGMVKKTPMVEYEH-RK--NGL---QAIVLREDD
ELIEVK-T---DN-QDIFLVTRKGMCIRFNE--VRVTRSMGVIGMRFE---DVIGMQMESQGESLLIVSENGMGKRTVISEFSAQNRGGKGVICYKCTTG
N-IVGAKLVNG-REIMLITTEGIVIRMSVDDISIIGRNTSGVKLMNIDQED-IKVASIAKVR--------------------------------------
------------
>tr|C0CSZ7|C0CSZ7_9FIRM DNA gyrase subunit A OS=[Clostridium asparagiforme] DSM 15981 GN=gyrA PE=3 SV=1
-------HHYVMCFTNTGRVYRLKAYEIPEAGRTARGTAIVNLLQPEKITAIIPMREDKYLFMATKGGMVKKTPMCEYEN-RK--NGL---QAIVLREND
ELIEVK-T---DN-EDIFLITKNGMCIRFHE--VRVTRSMGVIGMRFE---GVIGMQMASQGDSLLVVSENGMGKRTVINEFSAQNRGGKGVICYKITTG
C-LIGAKLVDG-REIMMITTEGIVIRMVVDDISVIGRNTSGVKLMAIDHDD-IKVASIAKVR--------------------------------------
------------
>tr|R6LXL7|R6LXL7_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:253 GN=gyrA PE=3 SV=1
-------HHYIMFFTNKGRMYRLKVYQIPECGRTARGTAIINLIQPERITAVITLRENKYLFMATKKGIVKKTSIMEYAN-RK--SGL---QAINLRDDD
DLIEVK-T---DN-KDIFLVTKHGQCIRFNE--VRTTRSMGVIGMNLS---DVVAMQLNTQGEHLLIVSEYGMGKRTAIEEFTVQHRGGKGIKCYKITTG
N-VVAAKAVND-TEVMIINTEGIIIQLMVNEVSVLGRITSGVKMIEMDSEE-VIVASMTRVR--------------------------------------
------------
>tr|F0Z5R0|F0Z5R0_9CLOT DNA gyrase subunit A OS=Clostridium sp. D5 GN=gyrA PE=3 SV=1
-------HHYIMFFTNTGRVYRIKGYEIPEASRTARGTAIINILQPEKITAMIPIKDGKFLFMATEKGLVKKTPITDYAN-RK--TGL---AAITLREDD
RLIEVK-T---DN-EDIVLVTKYGQCIRFSE--VRATRSMGVRGMNLS---RVIAMQMSTQGSDLLIVSDKGMGKRTNLDEFTTQNRGGKGVKCYKITTG
N-VVGMKAVND-SEIMIINTEGIIIRMQCSDISVLGRVTSGVKLINLAEG--DTVASVAKVR--------------------------------------
------------
>tr|R5XI46|R5XI46_9FIRM DNA gyrase subunit A OS=Firmicutes bacterium CAG:212 GN=gyrA PE=3 SV=1
-------HDYIMFFTNTGRVYRLKGYEIPEASRTSRGTAIINMLQPEKITAMIPIKDNLCLFMATEQGLVKKTPLREYVN-RK--KGL---AAITLRDDD
QLIEVK-T---DN-KDIILVTKYGQCIRFDE--VRTTRSMGVRGINLS---GVIGMQVDTQGDCLLIVSEKGMGKRTAMGEFTAQNRGGKGVKCYKITTG
N-VVGMKAVND-DEIMMINSDGIIIRMACDTISKYGRITSGVKLINLKEN--ETVVSIAKVR--------------------------------------
------------
>tr|V8BL55|V8BL55_RUMGN DNA gyrase subunit A OS=Ruminococcus gnavus CC55_001C GN=gyrA PE=3 SV=1
-------HHYIMFFTNTGRVYRLKGYEIPEASRTARGTAIINLLQPEKITAMIPIRDGQYLLMATEKGLVKKTPIKDYAN-RK--TGL---AAIVLREDD
KLIEVK-T---DD-QDVILVTKYGMCIRFSE--VRPTRSMGVRGMNLG---HVIGMQISDQGKYLLIASEKGMGKLTDMDEFTRQNRGGKGVKCYKITTG
D-VVGMKAVDD-SEIMMINTEGIVIRMKCSDISVYGRITSGVKLINLPEN--EKVASIAKVR--------------------------------------
------------
>tr|N2A764|N2A764_9CLOT DNA gyrase subunit A OS=Clostridium sp. ASF502 GN=gyrA PE=3 SV=1
-------HNYIMFFTNKGRVYRMKAYEIPEAGRTSRGTAIINLLQPEKITAMIPIRDNQYLFMATENGLVKKTPLYEYNN-RK--KGL---AAITLREDD
NLIEVK-T---DN-KEILLVTKYGQCIRFDE--VRSTRSMGVRGINLS---GVIGMQVHTQGDCLLIVSENGIGKRTIMGDFTIQNRGGKGVKCYKITTG
D-VIGMKAVND-DEIMMINSEGIIIRMSCADISKLGRITSGVKLINLKED--EKVVSLAKVR--------------------------------------
------------
>tr|R6DUZ8|R6DUZ8_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:230 GN=gyrA PE=3 SV=1
-------HHYLMFFTNKGRVYRLKAYEIPEASRTARGTAIINLLQPEKITAVIPIRDQKYLFMATKKGIVKKTSIVEYAN-RK--TGL---QAISLRDED
ELIEVK-T---NK-KDIILITKHGQCIRFNE--VRPTRSMGVIGMNLS---DLIGMQLNTQGDCLMIVSEYGMGKKTDINEFGVQHRGGKGVKCYKITTG
N-VVNAKAVND-NEVMLITTEGIIIQLKVSEISTLGRITSGVKLIDLDPED-IVVASMAKVR--------------------------------------
------------
>tr|V8C9H2|V8C9H2_9FIRM DNA gyrase subunit A OS=Ruminococcus lactaris CC59_002D GN=gyrA PE=3 SV=1
-------HHYIMFFTNTGRVYRMKAYEIPEAGRTARGTAIINLLQPEKITAIIPLREGKYLFMATEKGLVKKTPIQDYAN-RK--TGL---AAIALREDD
RLIEVK-T---DN-EDILLVTRDGMCIRFNE--VRSTRSMGVRGMNLT---NVIGMQTASQGTDLLIVSEKGMGKRTNMDEFTRQNRGGKGVKCYKITTG
N-VVGMKAVDD-SEIMIINTEGIIIRMKCSDISVYGRITSGVKLINLKEK--DKVASVAKVR--------------------------------------
------------
>tr|R5GBQ4|R5GBQ4_9FIRM DNA gyrase subunit A OS=Eubacterium sp. CAG:146 GN=gyrA PE=3 SV=1
-------HNYIMFFTNKGRVYRLKGYEIPESGRTARGVNIINLLQPEKITAIIPLLKQHYLVMATRNGLVKKTGFDEYKN-RK--NGL---AAISLREGD
ELIEVK-T---DE-EDIFLVSKEGQCIRFKL--VRETRSMGVIGMNLG---TVVGMQIRSEGDDLLIVSEKGMGKRTPLDEFTVQHRGGKGLRCYKITTG
Y-VVGVKTIKE-EEIMLITTEGIVIRMKSDSISVIGRNTSGVKLINIDSES-IKVASVAKVR--------------------------------------
------------
>tr|A7VDH0|A7VDH0_9CLOT DNA gyrase subunit A OS=Clostridium sp. L2-50 GN=gyrA PE=3 SV=1
-------HNYLMFFTNTGRVYRLKGYEIPEAGRTARGVAIVNLLQAEKITAVIPLKDGKYLFMATRNGMVKKTDISEYQN-RK--TGL---TAIVLRDND
ELIEVK-T---NG-DDIFLITKKGMTIRFNE--VRQTRSMGVKGIHLG---DVISMQMSSQGEKILLVTENGMGKRTLISEFNVQNRGGKGVKCYKITTG
D-LVGAKIVTE-NDIMIITTEGIIIRTSCEGISTLGRVTSGVKVINLNYDN-VKVASMTEVQ--------------------------------------
------------
>tr|R5NSC5|R5NSC5_9FIRM DNA gyrase subunit A OS=Eubacterium sp. CAG:603 GN=gyrA PE=3 SV=1
-------HHYLMFLTNMGKAYRLKAYQIPEAGRTARGTAIINLMQPEKISAVIPVKDSKFLFMTTKNGIVKKTPLIDFAN-RK--TGL---QAINLKDDD
ELIEVK-T---NN-RDIFLVTKYGMCIRFNE--VRKTRSMGVIGMNLE---GIVGMQMNNQGDSLLIVSENGLGKRTSIDEFKLQKRGGKGVRCYRINTG
Y-VVGVKAVND-HEIMMITNEGIIIQFKVNTVSEIGRNTFGVKLINIDKDN-IKVAKIAKVR--------------------------------------
------------
>tr|R5NP84|R5NP84_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:127 GN=gyrA PE=3 SV=1
-------HHYIMFFTNQGRVYRLKTYEIPESGRTARGTAIVNLLQPEVITAVIPIREGRYLIMATKNGMIKKTKITEYAN-RK--SGL---AAITLKEGD
ELIEVK-T---NN-KDIILITKQGMCIRFNE--VRSTRSMGVIGMSVA---DVIGMQLDTQGEALLIVSENGLGKRTLVEEFTPQHRGGKGVKCYKITSG
T-VVGFKAVND-NEIMLITNQGIVIRLLCKDISILGRITTGVKLINMDLED-ITVASIAKVR--------------------------------------
------------
>tr|F3AVC5|F3AVC5_9FIRM DNA gyrase subunit A OS=Lachnospiraceae bacterium 3_1_46FAA GN=gyrA PE=3 SV=1
-------HHYIMFFTNKGRVYRLKAYEIPEAGRTARGTAVINLLQPEKITATIPIKDGKYLFMATKKGLVKKTPIQDYMN-RK--TGL---AAISLREDD
LLIEVK-T---DN-QDILLVTKYGQCIRFNE--VRSTRSMGVRGMNLS---NIIGMQMSSQGKDMLIVSEKGMGKRTSMEEFTKQNRGGKGVKCYKITTG
N-VVGMKAVDE-SEIMIINTEGIVIRMKCSDISQYGRITSGVKLINLPE-K-ERVASVAKVR--------------------------------------
------------
>tr|T2KPY7|T2KPY7_9FLAO DNA gyrase subunit A OS=Formosa agariphila KMM 3901 GN=gyrA PE=3 SV=1
-------HQYMLFFTQKGKCFWMRVYEIPEGSKTSKGRAIQNLINQDKVMAFICTQNSHYVIMATKNGQVKKTSLEQYSR-RT--NGI---NAITIKEDD
VLMEAKLT---TGTSQVMLALKSGKAIRFE---TRPMRASGVRGITLSKD-DVVGMITVENEESVLVVSENGYGKRTYIDVYRITNRGGKGVKTISITTG
K-LVAIKTVS-ADDLMIINKSGIAIRIAVQDLRVMGRATQGVKLINLRS-G-DSIAAVAKVM--------------------------------------
------------
>tr|A6ER35|A6ER35_9BACT DNA gyrase subunit A OS=unidentified eubacterium SCB49 GN=gyrA PE=3 SV=1
-------HQYMLFFTQKGKCFWMRVFEIPEGSKTSKGRAIQNLINPDKVMAFICTQNSRYVIMATKKGQVKKTPLEQYSR-RT--NGI---NAITIKDDD
ELLEAKLT---RGDSQVMLAVKSGKAIRFE---TRPMRASGVRGIRLAD--DVVGMIAINDESEILVVSDKGYGKRSSIE-YRITNRGGKGVKTINVTTG
Q-LVAIKNVI-SDDLMIINKSGIAIRMDVSSLRVMGRATQGVRLIKVRE-D-DSIAAVAKVM--------------------------------------
------------
>tr|A0A0E9ZYX6|A0A0E9ZYX6_9FLAO DNA gyrase subunit A OS=Vitellibacter vladivostokensis GN=gyrA PE=3 SV=1
-------HQYMLFFTQKGKCFWMRVFEIPEGTRTSKGRAIQNLINPDKVKAFICTQNSHYVIMATKKGQVKKTPLEQYSR-RT--NGI---NAITIREDD
ELLEAKLT---TGDSQVMLAVKSGKAIRFE---TRPMRASGVRGITLGK--DVIGMVAVNEDSDILVVSENGYGKRSSIE-YRITNRGGKGVKTINITTG
K-LVAIKNVT-DDDLMIINKSGIAIRMAVSDLRVMGRATQGVRLIKVRE-D-DAIAAVAKAM--------------------------------------
------------
>tr|S7XEL7|S7XEL7_9FLAO DNA gyrase subunit A OS=Winogradskyella psychrotolerans RS-3 GN=gyrA PE=3 SV=1
-------HQYMLFFTQKGKCFWMRVYEIPEGSKTSKGRAIQNLINQDKVMAFICTQNSHYVIMATKQGQVKKTSLEQYSR-RS--NGI---NAITIKEDD
VLLEAKLT---TGESQVMLALKSGKAIRFE---TRPMRASGVRGIRLQEK-DVIGMIAVDDESNILVVSENGYGKRSSLE-YRITNRGGKGVKTISITTG
N-LVSIKNVT-EDDLMIINKSGIAIRMAVANLRVMGRATQGVKLINLKG-N-DSIAAVAKVM--------------------------------------
------------
>tr|A0A0R2RZ30|A0A0R2RZ30_9FLAO DNA gyrase subunit A OS=Cryomorphaceae bacterium BACL21 MAG-121220-bin10 GN=ABR84_05665 PE=4 SV=1
-------HQYMLFFTQKGKCFWMRVFEIPEGSKTSKGRAIQNLINQDKVKAFICTQNNHYLIMVTKMGQVKKTTLEQYSR-RT--NGI---NAITIKDGD
ELLEVKLT---TGDSQVMIAVRSGKAIRFE---TRPMRASGVRGITLGA--DVIGMIAVDGASDILVVTENGYGKRSSIE-YRITNRGGKGVKTINITTG
D-LVAIKNVS-LDDLMIINKSGIAIRMAVEDLRVMGRATQGVRLIKVRE-D-DSIAAVAKVM--------------------------------------
------------
>tr|F4B3A6|F4B3A6_DOKS4 DNA gyrase subunit A OS=Dokdonia sp. (strain 4H-3-7-5) GN=gyrA PE=3 SV=1
-------HQYMLFFTQKGKCFWMRVFEIPEGSKTSKGRAIQNLINQDEVKAFVCTGNNHFIIMATKKGQVKKTALEQYSR-RT--NGI---NAITIKDDD
ELLSVKLT---TGESQVMLALKSGKAIRFE---TRPMRASGVRGITLAD--DVIGMVSVNDESNILVVSEKGYGKRSSLE-YRITNRGGKGVKTISVTTG
E-LVAIKNVT-ADDLMIINKSGIAIRMEVASLRVMGRATQGVRLINLKG-N-DSIAAVAKVK--------------------------------------
------------
>tr|A0A0D7WAW0|A0A0D7WAW0_9FLAO DNA gyrase subunit A OS=Tamlana sedimentorum GN=gyrA PE=3 SV=1
-------HQYMLFFTQKGKCFWMRVYEIPEGSKTSKGRAIQNLINQDKVMAFICTQNSHYVIMATKNGQVKKTALEQYSR-RT--NGI---NAITIKDND
ELLEAKLT---TGNSQVMLALKSGKAIRFE---TRPMRASGVRGITLAEK-DVIGMVTVENEETVLVVTENGYGKRTFIDVYRITNRGGKGVKTISITTG
N-LVAIKSVT-SDDLMIINKSGIAIRLAVENLRTMGRATQGVKLINLKG-N-DSIAAVAKVM--------------------------------------
------------
>tr|A0A084THP9|A0A084THP9_9FLAO DNA gyrase subunit A OS=Mangrovimonas yunxiaonensis GN=gyrA PE=3 SV=1
-------HQYMIFFTQKGKCFWMRVYEIPEGTKTSKGRAVQNLINQDKVKAFICTQNSHYVIMATKKGQVKKTSLEQYSR-RT--NGI---NAITIKDGD
ELLEAKLT---TGDSQVMLAVKSGKAIRFE---TRPMRASGVRGITLADK-DVVGMITINDEETVLVVSENGYGKRTFIDIYRITNRGGKGVKTISVTTG
N-LVAIKSVS-KDGLMIINKSGIAIRMDVADLRTMGRATQGVRLINLKN-S-DSIAAVAKVV--------------------------------------
------------
>tr|A0A0A1GW36|A0A0A1GW36_9LACO DNA gyrase subunit A OS=Lactobacillus hokkaidonensis GN=gyrA PE=3 SV=1
-------HDRLLFFTSAGKVYSMKGYEVPEYGRSAKGIPVINLLGDEKISAVINVSHDKYLFFTTLHGTVKRTPVAAFEN-RS--NGL---KAITLKEND
QLMGVS-I---EE-QKMIIGTHLGYAVSFKG--VRSMRASGVRGIRLR---NVIGVDLLTQDSNVFIISERGFGKQTPASEYPIKGRGGKGIKTANVTNG
P-LVGLATVTA-EDIMLVTDKGVIIRFGIETVSQTGRATLGVHLIKMDDE--THVATMTKVA--------------------------------------
------------
>tr|A0A0R2AD59|A0A0R2AD59_9LACO DNA gyrase subunit A OS=Lactobacillus vaccinostercus DSM 20634 GN=FC26_GL000144 PE=4 SV=1
-------HDRLLFFTNAGKVYSMKGYEVPEYGRTAKGIPVINLLGDEKISAVINVQDDKYLFFTTLHGTVKRTAVSEFTN-RS--NGL---KAVTLKDDD
QLIGVS-V---DE-QNMIIGTHLGYAVSFKA--VRSMRASGVRGIRLR---NVIGVDLLNADSKVFVISEHGFGKQTAAAEYPIKGRGGKGIKTVNVTNG
P-LVGLTTVDD-EDIMLVTNRGVIIRFGIETVSQTGRATVGVHLIKMDDQ--TKVATMAKVD--------------------------------------
------------
>tr|A0A0R1RF55|A0A0R1RF55_9LACO DNA gyrase subunit A OS=Lactobacillus oligofermentans DSM 15707 = LMG 22743 GN=FC70_GL001300 PE=4 SV=1
-------HDMLLFFTNTGKVFSMKGYEIPEYGRTAKGIPIINLLGDEKISAVVNIADDNFLFFTTLKGTVKRTPVSEFTH-RN--NGL---KSITLKEDD
SLIGVS-I---SE-QNMIIGTHLGYAVSFKG--VRSMRASGVRGIRLR---NVIGVDILEADSKVFIISEKGFGKQTSASEYPIKGRGGKGIKTANVTNG
P-LAGMTTVTD-EDIMLVTDKGVIIRFDVANVSQTGRATLGVHLIKMDDE--THVATMTKVA--------------------------------------
------------
>tr|A0A0E9ME10|A0A0E9ME10_9PROT DNA gyrase subunit A OS=Sulfuricella sp. T08 GN=gyrA PE=3 SV=1
-------HDYILCFSNRGQVYWIKVYEVPQGSRGSRGKPFVNMLQ-EKINAILPVK-GHFIFMATASGIVKKTPLSDFSRPMK--RGI---IAINLDEND
YLIGVDIT---DGQHDVMLFTDGGKAVRFDE-AVRATRSRGVMGVRLG--KGVISLLVAENTQSVLTATENGYGKRTSIAEYTRHGRGTQGMIAIQTSNG
K-VVAATLVNAEDEIMLITTGGVLIRTRVSEIREMGRATQGVTLINLD-KG-EKLIGLERVV--------------------------------------
------------
>tr|A0A061NQH5|A0A061NQH5_9BACL DNA gyrase subunit A OS=Geomicrobium sp. JCM 19038 GN=gyrA PE=3 SV=1
-------HQTILFFTNKGKVYRLKGYEIPELSRTAKGIPIINLLQKEEISTVIPIDDDNYLFFLTKKGIAKRTPLSAYAN-RK--GGL---FAINLRDDD
ELHGVR-T---NG-DHVIIGTKNAMAIRFEE--VRSMRAGGVKAINLD--NDVVGMDIVGTGQKVLIVSNNGYGKRTNEDEFRIQNRGGKGLRASTLTTG
H-LVALRVISD-YDLMLITAKGVLIRIKADEISTLGRYAQGVTLIRVAD-D-EEVSSVAPFE--------------------------------------
------------
>tr|A0A061NQM5|A0A061NQM5_9BACL DNA gyrase subunit A OS=Geomicrobium sp. JCM 19037 GN=gyrA PE=3 SV=1
-------HRTILFFTNKGKVYRLKGYEIPDLSRTAKGIPIINLLQKEEISTVIPIDDDKYLFFLTKRGISKRTPLSAYAN-RK--GGL---FAINLRDDD
ELHGVR-T---DG-SDVIIGTQKAMAIRFQE--VRSMRAGGVKAISLD---DVVGMDIVKAGQKVLIVSNKGYGKRTNEDEFRIQNRGGKGLRASTLTTG
H-IVSLRVIDD-FDLMLITIKGVLIRIKSDEISTLGRYAQGVTLIRVSDD--EEVSTVAPIE--------------------------------------
------------
>tr|R5LTE9|R5LTE9_9CLOT DNA topoisomerase (ATP-hydrolyzing) OS=Clostridium sp. CAG:149 GN=BN500_01270 PE=4 SV=1
-------HHYMMFFTNTGRVYRLKAYEIPEAGRTARGTAIVNLIQPEKITATVPMKEDKFLFMATKNGMVKRTPMKEYEN-RK--NGL---QAIVLREDD
ELIEVK-T---DN-EDIFLVTKKGMCIRFHE--VRITRSMGVIGMKFD---DIIGMQMASQGECLLVVSEYGLGKRTPIEEFTSQLRGGKGVRCYRITTG
Y-LVGAKLVDG-RQIMLITNEGIIIKMRVNTISIIGRNTSGVKLMDIDPEG-VVVASIAKVR--------------------------------------
------------
>tr|R6RS37|R6RS37_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:58 GN=gyrA PE=3 SV=1
-------HHYIMFFTNTGRCYRLKAYEIPEAGRTARGTAIVNLLQPEKVTATIPMKNEKYLMMATKNGMVKKTRMEEYTN-RK--TGL---QAILLREDD
ELIEVK-T---DD-EDIFLATKYGLSIRFKE--VRITRSYGVIGMKLD---GVIGMQMESQGEYMLVASEKGYGKRTRISEFKSQLRNGRGLLCYNVTTG
C-LVGMKLVDE-RDIMLITNEGILIRMSVDDISVIGRNTSGVKLMSIDPDN-VRVATIAKVR--------------------------------------
------------
>tr|D7GRL3|D7GRL3_9FIRM DNA gyrase subunit A OS=butyrate-producing bacterium SS3/4 GN=gyrA PE=3 SV=1
-------HHYIMFFTNTGRCYRIKAYEIPEAGRTARGTAIVNLLQPEKVTAAIPMRDDKYLFMATKGGMVKKTRMCEYSN-RK--TGL---QAILLREGD
ELIEVK-T---DN-EDIFLATKFGMSIRFKE--ARITRSYGVIGMKLD---GVIGMQMASQGEYMLVASEKGYGKRTRISEFKLQLRGGKGLLCYNVTTG
N-LVGMKLLDG-RDIMLITNEGILIRMGVDDISIIGRNTSGVKLMSIDADD-VRVASIAKVR--------------------------------------
------------
>tr|R7AES3|R7AES3_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:43 GN=gyrA PE=3 SV=1
-------HHYVMFFTNKGRVYRLKGYEIPEAGRTARGTAIVNLLPPEKITSIVPMKDEKYLFMATRNGMVKKTPMKEYSN-RK--NGL---QAIVLRDDD
ELIEVK-T---DN-EDIFLITKKGMCIRFHE--VRVTRSMGVIGMKFD---GVIGMQMASQGECLLVVSENGYGKRTPIDEFTAQNRGGKGVRCYKIITG
D-LVGAKLVDE-RKIMLITNEGIIIKMAVSDISIIGRNTSGVKLMSIDAEG-IVVASIAKVR--------------------------------------
------------
>tr|E7GSB9|E7GSB9_CLOSY DNA gyrase subunit A OS=[Clostridium] symbiosum WAL-14163 GN=gyrA PE=3 SV=1
-------HHYVMFFTNTGRVYRLKAYEIPEAGRTARGTAIVNLLQPEKITSIIAMKDDKYLFMATRNGMVKKTSLKEYEN-RK--NGL---QAIVLREND
ELIEVK-T---DN-EDIFLVTKKGMCIRFHE--VRVTRSMGVIGMKFD---DVIGMQMSSQGECLLVASEYGYGKRTPIEEFNCQNRGGKGVRCYKIITG
D-LIGAKLVDS-REIMLITNEGIIIKMSVNDISIIGRNTSGVKLMSIDPDG-IAVASIAKVR--------------------------------------
------------
>tr|K9T3X2|K9T3X2_9CYAN DNA gyrase subunit A OS=Pleurocapsa sp. PCC 7327 GN=gyrA PE=3 SV=1
-------HDNILFFSDRGVVYTLNAYHIPAGSRSARGVPIVQMLAQEKITSIVAVQENDYLIMLTRKGYIKKTALSAFSNIRA--NGL---IAISLEEGD
QLRWVRLA---REEDSIILGSKGGMAIHFKA--LRPLRTRGVKAMKLK---ELISMDILPSGPWLLAITTCGYGKRVPVSQFRLQNRAGMGVRAIKF-QD
R-LVAIHVVN-EDEMMIVSNRGIIIRQAVDAISLQSRMATGVRVQRLDD-D-DAIAAVALVP--------------------------------------
------------
>tr|Q7NC97|Q7NC97_GLOVI DNA gyrase subunit A OS=Gloeobacter violaceus (strain PCC 7421) GN=gyrA PE=3 SV=1
-------HDTVLFFTNRGVVYALRGYQIPAGSRTAKGTPVVQLLPIEKVTSIVPVQSDEFLVMLTRTGFIKKTALAAFANLRA--NGL---IAIGLEEGD
ELRWVRRA---RAEDDILVGSRAGMAIRFRA--LRPLRARGVKSMELR---ELVSMDILSCGPWVLVVTADGFGKRVPFSEFRAQNRGGMGVIATKF-GD
E-LAALRVVS-EDELMIVTARGVIIRQQSEEISQQSRAATGVRVQRLDE-D-DTIVGVAVVP--------------------------------------
------------
>tr|L8LQ30|L8LQ30_9CHRO DNA gyrase subunit A OS=Gloeocapsa sp. PCC 73106 GN=gyrA PE=3 SV=1
-------HNHLLFFSNQGVVYSLNAYHIPIASRIARGTPIIQMLPTEKITSMVAVTDDQYLIMLTRQGLIKKTALSAFSHIRS--SGL---IAISLVEGD
QLRWVRLA---RSEDSVMIGSRHGMAIHFKA--LRPLRTRGVKAMKLR---ELISMDILPSGPWLLAITTGGYGKRVPVTAFRIQKRAGIGVKLIRF-KD
K-LAAIHVVN-EDELMMVTSRGIIIRQAVKAISLQSRSATGVRVQKLDQ-E-DAIAAVALVP--------------------------------------
------------
>tr|E0UBN7|E0UBN7_CYAP2 DNA gyrase subunit A OS=Cyanothece sp. (strain PCC 7822) GN=gyrA PE=3 SV=1
-------HDQILFFSDRGVVYVISAYQIPSSSRTARGVPIVQMLPKEKITSMVAVSEDQYLVMLTRQGYIKKTALSAYANIRA--NGL---IAITLSEGD
QLRWVRLA---KEEDSIIIGTRQGMAIHFKA--LRPIRARGVRSMKLK---EIISVDILPGGPWVLAITTGGYGKRVPVNQFRLQNRAGMGVKAIRF-QD
Q-LAAIHIVN-EDEMMIVTSRGIIIRQAVDAISPQSRMATGIRVQRLDD-D-DAIAAVALVP--------------------------------------
------------
>tr|K9XQN5|K9XQN5_STAC7 DNA gyrase subunit A OS=Stanieria cyanosphaera (strain ATCC 29371 / PCC 7437) GN=gyrA PE=3 SV=1
-------HDTVLFFSDRGVVYSISAYQIPAASRTARGVPIVQMLPQEKITSIVSVSDNEYLIMLTQKGNIKKTALSAFSNIRA--NGL---IAISLEEGD
ELRWVRLA---RTEDSVIIGTRKGMAIHFKA--LRPLRTKGVKSMKLK---ELISMDILPSGPWLLAITNNGYGKRVPVTKFRLQNRAGMGVRAIKF-ND
K-LAAIHVVN-EDELMIITNRGIIIRQAVDAISLQSRNATGVRVQKLDG-D-DAIAAVALVP--------------------------------------
------------
>tr|B7KBQ0|B7KBQ0_CYAP7 DNA gyrase subunit A OS=Cyanothece sp. (strain PCC 7424) GN=gyrA PE=3 SV=1
-------HDYILFFSDRGVVYVLGAYQIPSSSRTARGVPIVQMLPKEKITSMLAVSEDCYLIMLTRQGYIKKTVLSAYSNIRA--NGL---IAITLSEGD
QLRWVRLA---REEDSIIIGTRKGMAIHFKA--LRPTRARGVKSMKLK---EIISVDILPSGPWVLAITTGGYGKRVPVSQFRLQKRAGMGVKAIRF-HD
Q-LVAIHVVN-DDEMMMVTNRGIIIRQAVDAITPQSRMATGVRVQRLDE-D-DAIAAVALVP--------------------------------------
------------
>tr|Q8DJ59|Q8DJ59_THEEB DNA gyrase subunit A OS=Thermosynechococcus elongatus (strain BP-1) GN=gyrA PE=3 SV=1
-------HDRILFFSDRGLVYALAAYQIPSGSRQARGTPIVQLLPREKITSVIAVQEDEYLVMLTRKGFIKKTPLAAFSHIRS--NGL---IAISLEEGD
QLRWVRRT---REQDTIIIGSRQGMAIHFRA--LRPLRTRGVKSMNLR---ELVGMDILPAGPWVLVITTNGYGKRVPVQQFRLQNRAGMGITATKFKED
Q-LAALRIVN-GDELMIVTSRGIIIRQKVMDISSQSRSATGVRLQRLDE-D-DAIVTAAVLP--------------------------------------
------------
>tr|L8LYI5|L8LYI5_9CYAN DNA gyrase subunit A OS=Xenococcus sp. PCC 7305 GN=gyrA PE=3 SV=1
-------HNTLLFFSDRGVVYSLPAYQIPTASRTSRGTPLLQMLPQEKITSVVSVVEEEYLVMLTRKGNIKKTALSAFKSIRS--NGL---IAISLEEGD
QLRWVRLA---KPEDSIIIGTHNGMAIHFKV--LRPLRTKGVKSMKLK---ELISMDILPSAPWLLAITTNGYGKRVSVSKFRLQNRAGMGVRAIKF-SD
R-LAAIHVVN-ADEFMIVTNRGIIIRQVVDAISLQSRSATGVRVQRLDN-D-DAIAAVALVP--------------------------------------
------------
>tr|A0A0E4BEV7|A0A0E4BEV7_TANFO DNA gyrase subunit A OS=Tannerella forsythia 3313 GN=gyrA PE=3 SV=1
-------HATILFFTAKGRCFWKKVFEIPEGAKNAKGRAIQNFLNSDSVNAFIRIKNSHYLLFCTKKGVIKKTLLAAYSR-RQ--NGV---NAITLHEGD
GVIQVRLT---NGNNDVLIANRNGRAIRFH---VRVMRAAGVRGMTLDE--DAIGMVCIKDKETILVVSEQGYGKRSKIDDYRITNRGGKGVKTIHVTTG
K-LVGIKNVT-ENDLMIINKSGITIRMKVADLNIIGRATQGVRLINLEKRN-DEIASVCKVV--------------------------------------
------------
>tr|A0A0F2NSQ9|A0A0F2NSQ9_9GAMM DNA gyrase subunit A OS=Gammaproteobacteria bacterium BRH_c0 GN=gyrA PE=3 SV=1
-------HDTILCFTNAGKVFWLKVYQIPVAGRNSRGRPMVNLLPEERVTSILPVREDHFIFMATANGTVKKTSLQSFSRPRS--VGL---RAVELDDGD
HLVGTAIT---DGTCDVMLFTSGGKVARFREGDVRAMRARGVRGIRLAEQE-VISLIIPD-DQQILTVSENGYGKRTQADDFPAKGRGGQGVIAMQASNG
A-LVGALLVAEQDEIMLISDQGTLVRTRVGEVPSLGRNTQGVRLIRVR-QD-EKLVSVARIE--------------------------------------
------------
>tr|C5BSJ1|C5BSJ1_TERTT DNA gyrase subunit A OS=Teredinibacter turnerae (strain ATCC 39867 / T7901) GN=gyrA PE=3 SV=1
-------HDYILCFTNAGKVFWLKVYQIPVAGRQSRGRPMVNLLPEERITSILPVREDRFIVMATSQGTVKKTPLSQFARPRS--VGL---RAIDLVEGD
HLVGTAIT---DGQQDIMLLSSSGKAARFAEEQVRSMRSRGVRGIRMADHR-VIAMVIPA-GGKVLTVSENGYGKRTDVDDFPTKGRGSQGVIAMQVSNG
G-LVGAVQIFDGDELMMISDQGTLVRTRGDEVSLLSRNTQGVRLIKVR-ES-EHIVGVARIA--------------------------------------
------------
>tr|E8T2L0|E8T2L0_THEA1 DNA gyrase subunit A OS=Thermovibrio ammonificans (strain DSM 15698 / JCM 12110 / HB-1) GN=gyrA PE=3 SV=1
-------KDYLLIFTNQGKVYWLKAYEIPKMERPSRGHSIRNFLPGEIVSRIIPVKLNKDVFFVTQRGYVKRTPLKEFSNPRS--TGI---NAINLEPGD
RLVYVG-V---SDKDNIILISKNGRAIKFPV--VRQMRARGVRGILLD---DVVAAAVVEPDRFLLIVTEKGYGKRVEIEEFHLQRRGGKGLIAA--STG
K-VADATTLKDDEPIILVSKKGKIIRVKSADIPVYGRHTRGVRIQKLAE-D-DAVVSVSKVT--------------------------------------
------------
>tr|Q317S1|Q317S1_DESAG DNA gyrase subunit A OS=Desulfovibrio alaskensis (strain G20) GN=gyrA PE=3 SV=1
-------HQYLLLFTNKGRMFQLKVHQVPEGSRTAKGMHINNLL-EEWVNTALTIREEKYFLFSTRKGMVKRSSASLYAKARR--TGL---IAVGLREGD
ELIMVR-V---DDNCEVVLTTEKGIAIRFGC--VRPMRATGVKGIALS---DVVACVTVQGESEIMTVSRYGYGKRTLIDRYRVQSRGGKGVINF--TTG
E-VLGAMTVVSNDQLILLTSTNKIIRIGVKEVRSVGRATQGVRLVWLDE-G-DHVVGFDRVS--------------------------------------
------------
>tr|G1V2L0|G1V2L0_9DELT DNA gyrase subunit A OS=Bilophila sp. 4_1_30 GN=gyrA PE=3 SV=1
-------HQFLLMFTNKGRMHQLKVHQVPEGSRTAKGVHIANLV-KEWVNTILTVREDKSFLFATRRGMVKRSSAALYARSRK--GGL---IAVGLREDD
ELIMVR-I---TDDDFVVLATADGIAIRFSC--VRNMRATGVKGIALR---DVVACLVLKESPAIMTISALGFGKRTNVDLYRVQSRGGKGIINF--TTG
P-VIGAKSVLDDEALVLLTSTNKIIRMGVDEIRSVGRATIGVRLVKLDD-G-ARVVGFDTVN--------------------------------------
------------
>tr|B8DQA8|B8DQA8_DESVM DNA gyrase subunit A OS=Desulfovibrio vulgaris (strain Miyazaki F / DSM 19637) GN=gyrA PE=3 SV=1
-------HQYLLLFTNHGRMHQIKVHRVPEGSRTAKGVHIANLV-KELVTNVLTVREDRYFLFVTRRGMVKRSSASLYAKCRK--TGL---IAVGLRPDD
ELIMVR-V---DEHCHIVLTTGDGMAIRFQC--VRPMRATGVKGIALR---DVVACVILAETSMIMSVSANGFGKRTKADLYRVQSRGGVGVKNF--TTG
D-VIGAMPVRDDDALVLLTSTNKILRMGLNDVRSVGRATQGVRLVRLDE-G-ALVVGFDRID--------------------------------------
------------
>sp|Q1MQ89|GYRA_LAWIP DNA gyrase subunit A OS=Lawsonia intracellularis (strain PHE/MN1-00) GN=gyrA PE=3 SV=1
-------HQFLLLFTNKGRMHQLKVHQVPEGSRTAKGTHIANIV-KEWVTTILTVRDNKFFLFATRKGMVKRSSASYYARSRR--TGL---LAVGLREDD
ELIMVK-V---TNNDFIVLATAEGFAIRFSC--VRNMRAAGVKGIALR---DVVACLILQETPAIMTVSNLGYGKRTSIDLYRVQTRGGKGIINF--TTG
L-VIGAKPVSDDNALVLLTSTNKIIRMSVDEVRSAGRATMGVRLVKLDD-G-AYVVGFDTVD--------------------------------------
------------
>tr|B6WUP4|B6WUP4_9DELT DNA gyrase subunit A OS=Desulfovibrio piger ATCC 29098 GN=gyrA PE=3 SV=1
-------HQYLCLFTNKGRMHQLKVHQVPEGSRTAKGVHINNLL-EEWVTTVLAVREDKYFLFVTKRGMVKRSSASLYARCRK--SGL---MAVGLREDD
ELVVVR-I---REDSHIVLATADGYSIRFAC--VRPMRATGVKGIALR---DVVAGVILKETTEIMSISANGFGKRTRVDLYRLQSRGGKGIINF--TTG
P-VVGAMPVRDNDGLIMLTSANKVVRIGVEDVRSKGRATMGVMLVRLDE-G-AHVVGFDRVD--------------------------------------
------------
>tr|A0A0H3A423|A0A0H3A423_DESVV DNA gyrase subunit A OS=Desulfovibrio vulgaris subsp. vulgaris (strain DP4) GN=gyrA PE=3 SV=1
-------HQYLLLFTNHGKMHQLKVHQVAEGSRTAKGVHIANLL-KEWVTTVLSVREDRFFLFVTKRGMVKRSSASLYARARK--GGL---IAVGLRDDD
ELIMVR-I---HNDDHVVLTTGGGMAIRFAC--VRPMRATGVKGVALS---DVVACAVLPGSTEIMSISSNGYGKRTRIELYRLQSRGGKGVKNF--TTG
D-VIGAMPVRDDEALVLLTSTNKIIRMSVDEVRSVGRATMGVMLVRLDE-G-AIVVGFDRVD--------------------------------------
------------
>tr|A0A0B5I440|A0A0B5I440_9ARCH DNA gyrase subunit A OS=archaeon GW2011_AR20 GN=gyrA PE=3 SV=1
-------LNTLLFFTNKGKCFQLKTYELPLEGRYSRGKAIVNLLKQEKVNTILPISEGYLIF-MTRKGIIKKTKLNEYENPRS--SGL---QAIRLIEKD
ELVNVI-S---SGNDEVMIASKFGLASRFNE--ITSVRSVGVRGIRLN---DVIGMEKVNETSSLLTVTNNGYGKRTLISEYRLIRRGGKGVTNI--KNE
G-VVAIKPVYEDDEIMIMTEKGIVIRLPVKGISVIGRNTQGVKVIKLDN-N-DKVSSVAKIS--------------------------------------
------------
>tr|Q3A8M4|Q3A8M4_PELCD DNA gyrase subunit A OS=Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1) GN=gyrA PE=3 SV=1
-------HSFVLVFTDAGKVYWLKVHEIPQGGRASRGKAIVNLLQSENVTSILPVR-GRYIIFATQNGIVKKTDLMAYAN-RS--GGI---IALTIDEGD
RLVSTR-S---DG-MDVLLASQNGKAIRFPE--ARAMRSRGVRGMALE--DQVIGMEVVSDAATLVTVTEHGYGKRTNLDEYRQQGRGGKGIITIKTSNG
K-VVDIKLIND-FDLMFITDGGKVLRTRVADLSVIGRNTQGVRLMVLEP-G-ERIVAVAKLA--------------------------------------
------------
>tr|C6E7Q9|C6E7Q9_GEOSM DNA gyrase subunit A OS=Geobacter sp. (strain M21) GN=gyrA PE=3 SV=1
-------KDYLMFFTDAGKVYWLKVYEIPEAGRAARGKAIVNLLNAEKITTILPVK-DKFIMMATRNGVVKKTNMMEYSH-RV--GGI---IAVNLDEGD
KLITVA-T---DG-QDVLLASANGKAIRFKE--VRTVRSRGVRGMTLE--DVVIGMEILNEDSTIFTVTENGYGKRTEISEYRSQSRGGKGVITIKTTNG
N-VVDIKQVND-NDLMLITDQGKILRVPVAGFSIIGRNTQGVRLMVKEE-N-ERVVAVARLA--------------------------------------
------------
>tr|A0A0D2JFV3|A0A0D2JFV3_9DELT DNA gyrase subunit A OS=Desulfarculus sp. SPR GN=gyrA PE=3 SV=1
-------HSYLLVFTAMGRLYWLKVHELPQGGRATKGKAIVNLLNPDTVSTVLVVK-DKEVFMATQKGTVKKTNLDAFSR-RS--GGI---IAINLAEDD
YLVAVR-T---DK-MEIFLATQNGQAIRFSE--VRSMRAAGVKGIDLS--DAVVAMEAIAGTPTILTVTQNGYGKRTMLEEYPLRNRGGKGVITIKTTNG
L-VVGALVVEE-DEIMMVSEQGNIIRTKVGGISVIGRNTQGVKLINLSS-G-EKLVAVARLA--------------------------------------
------------
>tr|A1AJX6|A1AJX6_PELPD DNA gyrase subunit A OS=Pelobacter propionicus (strain DSM 2379) GN=gyrA PE=3 SV=1
-------KDYLLCFTDAGRMYWLKVYEIPEGNRTTKGKAVVNLVNMEKITTILPVK-HTFLFMATRNGVVKKTPLIEYSN-RS--GGI---IAVNLDDGD
KLIGVA-T---DG-KDVFLASRNGKAIRFSE--VRSMRTRGVRGMNLN--DHVIGMEIVHNGSTIFTVCENGYGKRTDLDEYRDQSRGGKGIITIKTNNG
S-VVNVMQVSD-NDLMVITDNGKILRVPVSGFSVIGRNTQGVRLITTEE-K-EKVVAVARLA--------------------------------------
------------
>tr|B3E999|B3E999_GEOLS DNA gyrase subunit A OS=Geobacter lovleyi (strain ATCC BAA-1151 / DSM 17278 / SZ) GN=gyrA PE=3 SV=1
-------KDFLLFFSDMGRVYRIKVYEIPEGSRTTKGKAVVNLVNEEKITAILPVKEDLYLLMATRNGVVKKTPLVEYLN-RT--TGI---NAVNLDEGD
KLISVA-T---DG-KDVFLASRHGKAIRFPE--ARPMRTRGVRGMNLE--DEVIGMEVVDPGSTIFTLTENGFGKRTDLDEYRGQSRGGKGLITIKTTNG
L-VVGVMQVNE-NQLMVITDQGKILRVPVAGFSVIGRNTQGVRVMVTEE-Q-EKIVAVAKLA--------------------------------------
------------
>tr|A0A0B6WWI0|A0A0B6WWI0_9BACT DNA gyrase subunit A OS=Pyrinomonas methylaliphatogenes GN=gyrA PE=3 SV=1
-------HAYLLIFTDDGQVYKLKVHEIPDAPPAARGKAIVNLINSRKLAGIVAVR--HYVVMVTRNGVIKKTALSEFQN-RS--NGI---NAINVDEGD
ALLDVV-T---DG-KRIFIATHDGMAIRFDE--VRPMRARGVRGIELR--DYVVALCAVSKHERMLSISEQGYGKQTPISDYRLQSRGGRGVINMRTTTG
K-VVAVFPVED-SEVMIITQHGKLIRIEASEIRKTGRSASGVRLIKTEE-G-DKVTSASLLE--------------------------------------
------------
>tr|Q74H88|Q74H88_GEOSL DNA gyrase subunit A OS=Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA) GN=gyrA PE=3 SV=1
-------KDFMLFFTDAGKVYQIKVYEIPEGGRATRGKAIVNLLNEEQITAILSVK-DRNIIMATRLGVVKKSPLREYAN-RS--GGI---IAVNLDDGD
KLIAVA-T---DG-QDVLLASKNGKSIRFHE--ARPMRSRGVRGMSLE--DVVIGMEIINPGSTIFTVTENGFGKRTELDEYRVQSRGGKGIITIKTTNG
C-VVDIMQVTE-NDLMLITDQGKILRIPVAQFSVIGRNTQGVRLMTAEQ-N-ERIVAVAKLA--------------------------------------
------------
>tr|A0A0A8WNZ4|A0A0A8WNZ4_9DELT DNA gyrase subunit A OS=Geobacter sp. OR-1 GN=gyrA PE=3 SV=1
-------KDYLMFFTDAGRCYWMKVYEIPEGGRATRGKAIVNLLNPEKISAILSVK-DRYIMMATRQGVVKKSPLREYSN-RS--GGI---IAVNLDEGD
KLITVA-T---DG-QDVLLASRNGKSIRFKE--ARPMRSRGVRGMTLE--DMVIGMEILNDGSSLFTVTENGYGKRTELSEYRLQSRGGKGIITIKTTNG
C-VVDIKQVTE-NDLMLITDQGKIIRMPVAGFSVIGRNTQGVRLMVTEA-E-ERIVAVAKLA--------------------------------------
------------
>tr|R7CEY2|R7CEY2_9FIRM DNA gyrase subunit A OS=Ruminococcus sp. CAG:9 GN=gyrA PE=3 SV=1
-------HHYLMFFTNTGRVYRLKAYEIPEAGRTARGTAIINLLQPECITAVIPLRDGHYLMMATKNGLVKKTPIKEYAN-RK--NGL---AAITLRDDD
ELIEVK-T---DD-KDIILVTKDGMCIRFKE--VRSTRSMGVRGMNID---GVVAMQLNSQGDCLLIVSANGMGKRTSMGEFTCQNRGGKGVKCYKITTG
D-VIGARAVND-NEVMLITTEGIIIRIACADISILGRITSGVKLINLTE-G-VTVASVAKVR--------------------------------------
------------
>tr|W2VNR5|W2VNR5_9FIRM DNA gyrase subunit A OS=Lachnoanaerobaculum sp. MSX33 GN=gyrA PE=3 SV=1
-------HNDIYFFTNKGRVYTIKGYKIPEASRTARGVAIVNLLNPEKISAIIPSEKDGYLFMVTKKGTIKKCQINLFDN-RK--NGL---AAINLTEDD
ELIEVK-T---HG-DDLIIVSKDGMCIRIND--IRAMRATGVRGMRLN---DVIGMQLASQGEYLLLVSEYGYGKRTRISEFKVQNRGGKGIICYKDNTG
K-LVGAKLVND-RELLLITTEGIIIRIEVSGISVLGRAASGVKLMNIDRED-TKIASIAKVR--------------------------------------
------------
>tr|R6VK65|R6VK65_9FIRM DNA gyrase subunit A OS=Firmicutes bacterium CAG:227 GN=gyrA PE=3 SV=1
-------HHYLMFFTNMGRVYRLKAYEIPEASRTARGTAIVNLLSAEKITAVIPVNAGEFLFMATRKGVVKKTPIEDYSN-RK--TGL---AAISLRDDD
ELIEVK-T---DG-KDVILITKFGQCIRFHE--VRQTRSMGVRGINLQ---EVIGMQLSCQGDYLLIVSEKGMGKRTSVGEFTCQNRGGKGVKCYKITTG
N-VVGVKAVNE-NEIMLITTEGIIIRLECKDISILGRITSGVKLMNLKND--ITVASIAKVR--------------------------------------
------------
>tr|C0CSE5|C0CSE5_9FIRM DNA gyrase subunit A OS=Blautia hydrogenotrophica DSM 10507 GN=gyrA PE=3 SV=1
-------HHYLMFFTNTGKVYRLKAYEIPEAGRTARGTAIINLLQPEKITAVIPLNEGKYLMMVTKKGLVKRTPILDYEH-RK--TGL---AAIVLRDED
ELIEVK-T---DN-KHIILVTKEGMCIRFKE--VRSTRSMGVRGMNLS---SVVGMQLDTQGDCLLFVSEKGMGKRTSISEFTCQNRGGKGVKCYKITTG
N-VIGVKAVNE-NEVMMITTEGIIIRLQCSDISMLGRITSGVKLINLDEG--VKVASVAKVR--------------------------------------
------------
>tr|R7EBL4|R7EBL4_9FIRM DNA gyrase subunit A OS=Roseburia sp. CAG:471 GN=gyrA PE=3 SV=1
-------HHYLMFFTNMGKVYRLKAYEIPEAGRTARGTAIINLLQAEKITAVLSLKQGQYLFMATKSGIVKKTPIQDYAN-RK--TGL---AAISLKDDD
ELIEVK-T---DN-KDIILVTKYGQCIRFKD--VRSTRSMGVRGINLS---GIIGMQLCSQGDYLLIASEKGMGKRTSMSEFSVQNRGGKGVKCYKITTG
N-VVGVKAVND-NEVMMITTEGIIIRIACSDISILGRITSGVKLMNLDEK--VSVASIAKVR--------------------------------------
------------
>tr|R6KNC3|R6KNC3_9FIRM DNA gyrase subunit A OS=Blautia sp. CAG:237 GN=gyrA PE=3 SV=1
-------HHYVMFFTNTGRVYRLKAYEIPEAGRTARGTAIINLLQPERITAVIPISEGHYLMMATRKGLVKKTPIQDYAN-RK--VGL---AAIALRDDD
ELIEVK-T---DD-KDIILVTKYGQCIRFKE--VRSTRSMGVRGINLL---GVVAMQLNTQGYYLLVVSENGMGKRTSISEFTCQNRGGKGVKCYKITTG
N-VIGAKAVNE-NEIMMITTEGIIIRLQCADISILGRITSGVKLINLSK-G-VTVASFAKVR--------------------------------------
------------
>tr|D4J4X4|D4J4X4_9FIRM DNA gyrase subunit A OS=Coprococcus catus GD/7 GN=gyrA PE=3 SV=1
-------HDYILFFTNKGRVFRLKGYEIPEASRIARGTALINLLQPEKVTATIPLENDKYLFMATKNGMVKKTSIMEYIN-RK--TGL---LAIGLREDD
ELIEVK-T---DE-DLIYLVSQKGMSICFKQ--VRATRSMGVIGMDLD---DIVGMQVSSQGEAVLIVSEKGLGKRTMLEEFNVQNRGGKGLKCYKITTG
L-VVGVKCVNE-DELMIITTGGIIIRMPVEGISILKRITSGVKLIQLDEG--SVVASIAKIR--------------------------------------
------------
>tr|U2D2H6|U2D2H6_9FIRM DNA gyrase subunit A OS=Blautia sp. KLE 1732 GN=gyrA PE=3 SV=1
-------HHYLMFFTNTGRVYRLKAYEIPEAGRTARGTAIINLLQPEKITAVIPLREGHYLMMATKKGLVKKTPIKDYEN-RK--TGL---TAIVLRDDD
ELIEVK-T---DN-KDIILVTRDGQCIRFKE--VRSTRSMGVRGMNLT---GVVAMQLNTQGDYLLVVSENGMGKRTAMSEFVVQNRGGKGVKCYKITTG
N-VVGAKAVNE-NEIMMITTEGIIIRLQCADISVLGRITSGVKMINLTE-G-VTVASIAKVR--------------------------------------
------------
>tr|R7CVV7|R7CVV7_9BACE DNA topoisomerase (ATP-hydrolyzing) OS=Bacteroides sp. CAG:462 GN=BN666_01433 PE=4 SV=1
-------HNTMLFFTQKGRCYWLKVYEIPEGSKNSKGRAIQNLLNPDMVTAFIRVKNNHYLLFCTQKGTIKKTCLEQYSR-RQ--NGV---NAINIVDDD
RVIEVRMT---NGDNEIIIANRNGRAIRFH---VRVMRATGVRGITLD-G-DVIGMICIKDKESIMVVSEQGYGKRSDIE-YRITNRGGKGVKTLNITTG
K-LVAIKSVT-ENDLMIINKSGITIRLKVADVRIMGRATQGVRLINLEKRN-DQIASVCKVN--------------------------------------
------------
>tr|G5G978|G5G978_9BACT DNA gyrase subunit A OS=Alloprevotella rava F0323 GN=gyrA PE=3 SV=1
-------HDTMLFFTACGRCYWLKAYELPEGTKNAKGRAIQNMLNKDAINACLYVKNSHYVVFCTKNGTIKKTSLSDYSR-RA--NGV---IAINIREDD
RVVSAVLT---NGTDELVIANRNGRAIRFN---VRVMRATGVRGITLD---DVVGMVCVNDKETIMVVSEKGFGKKSAIE-YRKTNRGGKGVKTLQITTG
K-VAAIKSVT-DDDLMIINKSGIVIRLKTSEVRVMSRATQGVKLIDLKKRN-DMISSVCKCP--------------------------------------
------------
>tr|K2JN64|K2JN64_9GAMM DNA gyrase subunit A OS=Gallaecimonas xiamenensis 3-C-1 GN=gyrA PE=3 SV=1
-------HDTILCFSSRGRLYWLKVYQLPLASRTARGRPIINLLP-ERITAIL--PEGKYIFMATAFGTVKKTALTEYSR-RS--NGI---IAVNLNEGD
ELIGVTIT---DGSNEVMLFSDEGKVVRFSEDQVRAMRATGVRGINLE---GVVSMVIPSAEVDILTVTENGYGKRTAQDEYPAKSRATKGVVSI--SNG
K-VVGAVAVE-SDEIMLISNRGTLVRTRVNEVSRVGRNTQGVTIIRTAT-D-EKVVGLQRIA--------------------------------------
------------
>tr|K1YS63|K1YS63_9BACT DNA gyrase subunit A OS=uncultured bacterium (gcode 4) GN=gyrA PE=3 SV=1
-------HDTMLCFSNRGKVYWLKVYLLPQGSRTARGKPLVNLLP-ERINTILPIRANNYIFMATAFGTVKKVGLEHFSNPRS--NGI---IALDLSPGD
NLIGAAIT---DGKQEVMLFSDAGKAVRFDEGQVRAMRAHGVRGMRIKD--QIISLIIVKPDEAILIATENGYGKRTAVTDFPNVNRGAQGVIAVQVSNG
K-AVSAIQVCAGSEIMLISNQGTLVRIRVDEVSLIGRNTQGVKLINLS-VD-ETLVGVQQVE--------------------------------------
------------
>tr|K2EQJ1|K2EQJ1_9BACT DNA gyrase subunit A OS=uncultured bacterium (gcode 4) GN=gyrA PE=3 SV=1
-------HDTILCFSNKGKVYWLKVYLLPQGNRTSRGKPLINLFP-ERINTILPIRPNHYIFMATAKGTVKKVPLEQFSNPRS--NGI---IAVDLQPDD
NLINVALT---DGKQEIMLFSDAGKAVRFAEDQVRSMRAMGVRGMRLKDQK-LISLVIAN--GAILTATENGYGKRTAISEFSVVNRGAQGVIAIQVGNG
K-AVCAIQVDAGDEIMLISSQGTLVRTRVDEISVIGRNTQGVRLINLG-EG-ENLVGVQRVE--------------------------------------
------------
>tr|A0A0M2HUM3|A0A0M2HUM3_9MICO DNA gyrase subunit A OS=Microbacterium hydrocarbonoxydans GN=gyrA_1 PE=3 SV=1
-------HHWLLFFTDKGRVYRSKTYEVPESGRDAKGTHVANLLAPEKIAQILDIRAD-YLVLATRDGLVKKTSLSSYDT-RQ--GGV---IAIRLNDED
ELVSAL-----NAEDDILLISRRGMSVRFSE--LRPMRTAGVKGMKFR-D-GLLSASVAAPGQYVFVVTDGGYAKRTAIDEYRVQGRGGFGIKVAKLNRG
T-LAGGLMVAD-DEVLVVLSSGKVVRSAVAEVPA-GRDTMGVVFARTTE-A-DRILAIARNG--------------------------------------
------------
>tr|A0A0F0LLU7|A0A0F0LLU7_9MICO DNA gyrase subunit A OS=Microbacterium azadirachtae GN=gyrA_1 PE=3 SV=1
-------HHWLLFFTDKGRVYRTKTYEVPEAGRDAKGQHVANLLAPEKIAQILDIRAQ-YLVLATRGGLVKKSRLGDYDT-RQ--GGV---IAIRLREDD
ELVSAF-----DATDDVLLISRHGMSVRFQE--LRPMRTEGVKGMRFN-E-DLLSASLVTGDGFVFVVTDGGYAKRTSVDEYRVQGRGGQGIKVAKLNRG
I-LAGGLIVQD-DEVLVVLASGKVVRSAVAEVPA-GRNTMGVVFARAAE-D-DRILAIARNI--------------------------------------
------------
>tr|W7YBL2|W7YBL2_9BACL DNA gyrase subunit A OS=Paenibacillus pini JCM 16418 GN=gyrA PE=3 SV=1
-------HHYLLFFTDKGKVYKLKAYEIPELGRTARGTAIINLIQQETVYAVIPVQSDKYLLFATRKGIVKKTPLEDYIN-RK--GGL---IAINLREDD
SLIEVK-T---EG-QEMIMGTAQGMSIRFSE--VRSMRATGVKGINLD---NVIGMDVVDQDLDVLIVTSKGYGKRTPASDYRSQTRGGKGIKTINVTNG
P-VVALKIVKE-EDLMIITSSGTLIRTSMEGISTMGRYTQGVKLINIRDD--DSVGTVCIAD--------------------------------------
------------
>tr|A0A0B0HXS6|A0A0B0HXS6_9BACL DNA gyrase subunit A OS=Paenibacillus sp. P1XP2 GN=gyrA_2 PE=3 SV=1
-------HHYLMFFTDRGKVYRLKAYEIPELSRTARGTAIINLIQQETINAVIPVENDKYLFFVTRSGIVKKTPLEDYVN-RK--GGL---IAINLREDD
SLIEVK-T---DG-QEVIMATAQGMSIRFSE--VRSMRATGVKGITLD---DVIGMDVVDKDLDTLIVTAKGYGKRTPLSDYRSQTRGGKGIKTLNVTNG
P-VVGLKVVKD-EDLMIITSSGTLIRTSIDGISIMGRYTQGVKLINIRED--DTVATVCRVD--------------------------------------
------------
>tr|A0A0R2VUC8|A0A0R2VUC8_9FLAO DNA gyrase subunit A (Fragment) OS=Polaribacter sp. BACL8 MAG-120419-bin8 GN=ABR93_04035 PE=4 SV=1
-------HQYMLFFTQSGKCFWMRVYEIPEGSRTSKGRAIQNLINQDKVKAFICTQNSHYVIMATKKGIVKKTTLEQYSR-RT--NGI---NAIGVREGD
ELLEAKLT---TGTSQVFLGLKSGKAIRFE---TRPMRASGVRGVSLADQ-DVIGMITVHNEDHILVVSEKGYGKRSSME-YRVTNRGGKGVKTISITTG
G-LVAIKNVT-SDDLMIINKSGIAIRLGVEDLRVMGRATQGVKLINIRE-N-DSIAAVAKVM--------------------------------------
------------
>tr|A0A0D5YVV9|A0A0D5YVV9_9FLAO DNA gyrase subunit A OS=Muricauda lutaonensis GN=gyrA PE=3 SV=1
-------HQYMLFFTQKGKCFWMRVYEIPEGSRTSKGRAIQNLINQDKVKAFICTRNSHCVIMATKKGTVKKTSLEQYSR-RQ--NGI---IAINIREDD
ELLEAKLT---TGTSQILLGLKSGKAIRFE---TRPMRAAGVRGITLAE--DVIGMVSVNNEDDILVVSENGYGKRSNID-YRITNRGGKGVKTISITTG
N-LVAIKNVS-SDDLMIINKSGIAIRMSVEDLRVMGRATQGVKLINLKD-K-DSIAAVAKVM--------------------------------------
------------
>tr|E6XDR3|E6XDR3_CELAD DNA gyrase subunit A OS=Cellulophaga algicola (strain DSM 14237 / IC166 / ACAM 630) GN=gyrA PE=3 SV=1
-------HQYMLFFTQKGKCFWMRVYEIPEGSKSSKGRAIQNLISSDKVKAFICTQNSHYVIMATKKGIVKKTSLEQYSR-RQ--NGI---NAIGIREDD
ELLEAKLT---TGTSEIFLGLKSGKAIRFE---TRPMRASGVRGITLAD--DVIGMVSVQNEEEILVVSEKGYGKRSSIE-YRVTNRGGKGVKTISITTG
G-LVAIKNVS-SDDLMIINKSGIAIRMSVEDLRVMGRATQGVRLINIKG-K-DSIAAVAKVM--------------------------------------
------------
>tr|A0A0R2TP80|A0A0R2TP80_9FLAO DNA gyrase subunit A OS=Cryomorphaceae bacterium BACL7 MAG-121220-bin8 GN=ABR90_06620 PE=4 SV=1
-------HQYMLFFTQKGKCFWMRVFEIPEGSKTSKGRAMQNLINQDEVKAFICTQNSHYVIMTTKKGQVKKTSLEQYSR-RS--NGI---NAITIKDGD
ELLEAKLS---NGNSQVLIAVKSGKCIRFE---TRPMRASGVRGIRLKD--DVVGMISVNDSSDILVVSENGYGKRSSLE-YRITNRGGKGVKTISITTG
S-LVSIKNVS-SDDLMIINKSGIAIRMEVSSLRVMGRATQGVKLINLKD-S-DSIAAVAKVV--------------------------------------
------------
>tr|I0WG51|I0WG51_9FLAO DNA gyrase subunit A OS=Imtechella halotolerans K1 GN=gyrA PE=3 SV=1
-------HQYMLFFTQKGKCFWMKVYEIPEGSRTSKGRAIQNLINTDKVKAFICTQNTHFVIMATKKGIVKKTTLEAYSR-RQ--NGI---NAITVREDD
ELLEALLT---TGKSQVMLAVKSGKAIRFE---TRPMRASGVRGISLAE--DVVGMIAIENEETVLVVSENGYGKRTFIDVYRITNRGGKGVKTISITTG
N-LVAIKSVT-SDDLMIINKSGIAIRLTVEDLRVMGRATQGVRLINIKG-D-DSIAAVAKVM--------------------------------------
------------
>tr|A4CK42|A4CK42_ROBBH DNA gyrase subunit A OS=Robiginitalea biformata (strain ATCC BAA-864 / HTCC2501 / KCTC 12146) GN=gyrA PE=3 SV=1
-------HQYMLFFTQKGQCYWLRVFEIPEGSRTSKGRAIQNLINQDKVKAFICTQNSHFVIMATKKGVVKKTSLEQYSR-RQ--NGI---IAIGIREGD
ELLEARLT---TGSSQIFLGLKSGKAIRFE---TRPMRASGVRGITLAD--DVIGMVSVHDDEDILVVSENGYGKRSSLD-YRITNRGGKGVKTISISTG
G-LVAIKNVS-SDDLMIINKSGIAIRMSVEDLRTMGRATQGVRLINLKD-N-DSIAAVAKVM--------------------------------------
------------
>tr|U2PB91|U2PB91_LACBR DNA gyrase subunit A OS=Lactobacillus brevis ATCC 14869 = DSM 20054 GN=gyrA PE=3 SV=1
-------HDMLLFFTNTGKVYRMKGYEIPEYGRTAKGIPVINLLGNEHVQAVINVADNRDLFFTTVQGTVKRTPVDEFAN-RS--NGL---KAINLKEDD
ELIDVD-I---NA-ANMIIGTHLGYAVSFAA--VRSMRATGVRGIRLR---HVIGASVLKPDSKVFVISEKGYGKQTAAAEYPIKGRGGKGIKTVNVSNG
P-LAGLTTLDD-EDIMLVTNKGVMIRFSASDVSETGRATLGVHLIRLADD--TAVATMAKVA--------------------------------------
------------
>tr|A0A0R1LIY8|A0A0R1LIY8_9LACO DNA gyrase, A subunit OS=Lactobacillus acidifarinae DSM 19394 GN=FD25_GL002328 PE=4 SV=1
-------HDMLLFFTNTGKVYRMKGYEIPEYGRSAKGIPVINLLGNEHVQAVINVATERDLFFTTVHGTVKRTPVDEFAN-RS--NGL---KALNLKDGD
ELMNVA-I---KN-ANMIIGTHLGYAVSFAA--VRSMRATGVRGIRLR---HVIGASVLKPTDHVFVISEKGYGKQTAATEYPIKGRGGKGIKTVNVSNG
P-LAGLTTVAD-EDIMLITNKGVMIRFSVADVSETGRATLGVHLIRLNDD--AKVATMAKVA--------------------------------------
------------
>tr|A0A0K2BKS0|A0A0K2BKS0_9GAMM DNA gyrase subunit A OS=Candidatus Baumannia cicadellinicola GN=gyrA PE=3 SV=1
-------HDTILLFSSLGRMYWMKVYQLPTASRGSRGRPIVNLLP-ERITTILPVREGLNIFMATASGTVKKTALTEFSRPRS--TGI---IAVNLHGGD
ELIGVNLT---NGSNEVMLFSAYGKVVRFSESQVRSMRATGVRGINLA--EGVVSLIVPRA-GHILTVTRHGYGKRTAQVEYPTKSRYTQGVISIKVSNG
E-VVGAVQVNDNDQIMLITDAGTLVRTRVSEVSIFGRNTQGITIIRTA-EA-EHVVSLQRVA--------------------------------------
------------
>tr|A0A088MYG6|A0A088MYG6_9GAMM DNA gyrase subunit A OS=Candidatus Baumannia cicadellinicola GN=gyrA PE=3 SV=1
-------HDTILLFSSRGRMYWMKVYELPAASRGSRGRPIVNLLP-ERITTIL--PEGHNVFMATASGTVKKTSLIEFSR-RS--AGI---IAVNLHGGD
ELIGVDLT---DGSNEVMLFSAYGKVVRFSENQVRSMRATGVRGINLT---GVVSLIIPRADGHILTVTRHGYGKRTVQAEYPTKSRSTQGVISI--SNG
E-VVGAVQVD-SDQIMMITDAGTLVRTWVSEVSIIGRNTQGITLIRTAE-D-EHVVSLQRVA--------------------------------------
------------
>tr|H6KYZ2|H6KYZ2_SAPGL DNA gyrase subunit A OS=Saprospira grandis (strain Lewin) GN=gyrA PE=3 SV=1
-------HDYLLLFTQKGRCHWKRVYEIPEGGKSTKGRAIQNFVEEDKVKAYIVLKDSHFLTFATRKGLVKKTPLRAYSR-RS--AGI---NAITFKEGD
ELLEVKLT---NGKSEIMLAASNGKAIRFS---VRSMRAAGVKGMRME---VLIGMITFAEK-KIANISENGLGKCTELE-YRIQSRGGKGIKTMQLTTG
K-LIAIKAVT-RDDLMIINKSGLTIRFTVEQLPINGRSTQGVKLINLKG-G-DAIADVALIK--------------------------------------
------------
>tr|A0A0R1T291|A0A0R1T291_9LACO DNA gyrase subunit A OS=Lactobacillus saerimneri DSM 16049 GN=FC54_GL000609 PE=4 SV=1
-------HDVLLFFTNVGKVYRMKGYEIPEYGRAAKGIPIINLLDDEKIQAVIKVTAAHYLFFTTLHGRVKRTAVEEFAN-RR--NGL---KAINLRDGD
ELIKVV-T---DG-QNIIIGTHNGYAVSFAE--VRSMRASGVLGVRLR---DVIGSAILDPKSNVLVVSEKGYGKQTPASEYGIKNRGVMGVKTLNITNG
A-LAGLTTVKD-EDILVITTGGVMIRFKVADVSQTGRATLGVRLMKLDDD--AQVSTMTKVE--------------------------------------
------------
>tr|A0A0R2KIX7|A0A0R2KIX7_9LACO DNA gyrase subunit A OS=Lactobacillus ceti DSM 22408 GN=IV53_GL000029 PE=4 SV=1
-------HDELFFFTNVGKVYRMKGYEIPEYGRTAKGIPVINLLGEEKIQAVIKVTKEQYLFFTTLYGRVKRTSVAEFQN-RK--NGL---KAINLRDND
ELIKVV-T---DG-KNMIIGTHDGYAVSFPE--VREMRASGVRGVRLR---DIIGSAILEPENNVLVVSEKGYGKQTPASEYAVKSRGIKGVKTLNVTNG
K-LAGLNSVNT-EDMLVITDAGVIIRFAVADVSQTGRATLGVRLMRLDQD--DRVATMTKVE--------------------------------------
------------
>tr|W0JAP2|W0JAP2_9BACT DNA gyrase subunit A OS=Opitutaceae bacterium TAV5 GN=gyrA PE=3 SV=1
-------HDYIMFVTSSGQCLAKKVYDVPEGARTTKGKSVSSFLREEKIAAMLCFQ--RYLVMATKRGIVKKTPLSDYLGTHE--GGL---IGINLAEGD
TVIGTVLT---TGSDEIILVSHQGLAVRFRE-LFRPTRTGGVTGMRFKD--QLDVIEVVDHSAKFLVASEAGLGVRTRFEDYRLINRGGRGVWAI--PSI
N-IAGALSVKDEDEIMLLTAKGQSVRCPVRDIREVNRGGKGVKLLTLAE-G-DKLLSIAKVV--------------------------------------
------------
>tr|B1ZTK3|B1ZTK3_OPITP DNA gyrase subunit A OS=Opitutus terrae (strain DSM 11246 / PB90-1) GN=gyrA PE=3 SV=1
-------HDYILFFTSIGQCHAKKVYDIPEGTRASKGKSVSSFLREEKIAAMLCVK--RYLVTATKRGIIKKSALSDYANARE--GGL---IGINLQEAD
SVIGTVLT---TGENELILVSHQGLAVRFRE-LFRATRTGGVTGMRFKK--YLDVIEVVDHEAKFLVASEAGLGVRTRFEDYRLINRGGSGVWAI--PSI
K-LAGALSVREDDEVMLLTAKGQSIRCPVKDIRETNRGAKGVRLVTLEP-G-DKLLSIARIV--------------------------------------
------------
>tr|A0A0J5PAX5|A0A0J5PAX5_9LACT DNA gyrase subunit A OS=Fructobacillus sp. EFB-N1 GN=gyrA PE=3 SV=1
-------HDSLFFFTNKGKVYRMKGYEIPEYGRQAKGIPVINLLNEEKIQTLLSVNSQDNLFFVTRKGVVKRTQVQDFAH-RT--SGL---KALTLRDDD
EILKVL-T---DG-QNIVIATMNGYSVTFAE--VRLMRAAGVRGINLR---GVIGADILTPDSKVFVISQKGYGKQTAATEYPVKGRGGKGIKTATITNG
P-LAGMVTVDD-EDIMVTTDQGVMIRFSVDTVSQTSRATQGVRLIRLEDD--SKVATLTKLE--------------------------------------
------------
>tr|A0A0K8MPM1|A0A0K8MPM1_9LACT DNA gyrase subunit A OS=Fructobacillus fructosus GN=gyrA PE=3 SV=1
-------HDSLFFFTNKGKVYRMKGYEIPEYGRSAKGIPVINLLNDEAIQSLLTVHSEDNLFFVTRKGVVKRTKVQDFAN-RT--SGL---KALTLREDD
EILKVL-T---NG-QNIIIATHNGYSVTFAE--VRLMRAAGVRGINLR---GVVGADILVPDSKVLIITEKGYGKQTAAAEYPVKGRGGKGIKTATITNG
P-LAGMVTVDD-EDIMVTTNLGVMIRFSIADVSTTGRSTQGVRLIRLEDD--SKVATFTKLE--------------------------------------
------------
>tr|A0A0N1S1C8|A0A0N1S1C8_LEUME DNA gyrase subunit A OS=Leuconostoc mesenteroides subsp. mesenteroides J18 GN=gyrA PE=3 SV=1
-------HDTLLFFTNKGKVYRMKGYEVPEYGRQAKGIPVVNLLNEEKIQTVINVRSNDYLFFVTRLGVVKRTAVKEFAN-RT--NGL---KALTLHDDD
EVLSVQ-T---DG-QNIIIATHNGYSVSFAE--VRVMRAAGVRGIRLR---GVVGSDVLEKDHNVLIITEKGYGKQTPVSEYPIKGRGGKGIKTANITNG
P-LAGMTIVSQ-EDIMVTTTQGVMIRFNVDSVSQTGRATLGVRLIRLEGN--AKVATLAKVE--------------------------------------
------------
>tr|D8MCT6|D8MCT6_LEUGG DNA gyrase subunit A OS=Leuconostoc gelidum subsp. gasicomitatum (strain DSM 15947 / CECT 5767 / JCM 12535 / LMG 18811 / TB1-10
-------HDTLLFFTNKGKVYRMKGYEVPEYGRQAKGIPVVNLLKEEKIQTVINVRSKDYLFFVTRLGVVKRTAVSEFSN-RT--NGL---KALTLRDDD
EVLSVQ-T---DG-QSIMIATKDGYSVRFTE--VRIMRAAGVRGIRLR---GVIGSDVVSLNDNVLVITEKGYGKQTPVSEYPIKGRGGKGIKTANITNG
T-LAGMIIVHD-EDIMVTTTQGVMIRFTTESVSQTGRATLGVRLIRLEDG--AKVATLAKVE--------------------------------------
------------
>tr|B1MW34|B1MW34_LEUCK DNA gyrase subunit A OS=Leuconostoc citreum (strain KM20) GN=gyrA PE=3 SV=1
-------HDTLLFFTNKGKVYRMKGYEVPEYGRQAKGIPVVNLLNEEKIQAVISVRSKDYLFFVTRLGVVKRTAVSEFAN-RT--NGL---KALTLHDGD
EVLSVQ-T---NG-QSILIATQAGYSVRFAE--VRVMRAAGVRGIRLR---NVIGADVVTSSDNVLVITEKGFGKQTPASEYPIKGRGGKGIKTANITNG
V-LAGMTIIHH-EDIMVTTTQGVMIRFAADSVSQTGRATLGVRLIRLEEG--TKVATLTKVD--------------------------------------
------------
>tr|K0D800|K0D800_LEUCJ DNA gyrase subunit A OS=Leuconostoc carnosum (strain JB16) GN=gyrA PE=3 SV=1
-------HDTLLFFTNKGKVYRMKGYEVPEYGRQAKGIPVVNLLNEEKIQTVITVKSQDYLFFVTRQGVVKRTAVSEFSN-RT--NGL---KALTLRDND
EVLSVQ-T---DG-QSIIIATKDGYSVRFSE--VRIMRAAGVRGIRLR---GVIGSDVLSQQDNVLIITENGYGKQTPATEYPIKGRGGKGIKTANITNG
S-LAGMIIINN-KDIMVTTTQGVMIRFAASTVSQTGRATMGVRLIRLEDG--AQVATLAKVD--------------------------------------
------------
>tr|A6DH72|A6DH72_9BACT DNA gyrase subunit A OS=Lentisphaera araneosa HTCC2155 GN=gyrA PE=3 SV=1
-------HDYIMFFTNFGRMHWLKVYDIPEATRVSKGKAMVNLLEKEYVRAMISVD-DRFIMMSTRNGVVKKTALAAFKNMRK--KPI---KAIVLDEDD
DLIEAKLT---DGNKKIILSTREGIACHFKE--CRTQRTRGCRGIRLS---QVVAMSIVEESEDILVVTAKGMGKRSCVDDYRLTKRGAKGVRNI--K-D
Y-VVEVMMIEDTDEIIMTTMEGLMVRISAEPIRSLGRASQGVTIMKFKK-A-SDLIISARVV--------------------------------------
------------
>tr|A0A0A2DT26|A0A0A2DT26_9PORP DNA gyrase subunit A OS=Porphyromonas sp. COT-239 OH1446 GN=gyrA PE=3 SV=1
-------HATMLLFTQRGRCYWLKVYEIPEGSKSAKGRAIQNLLNPDKVNAFIRIKNSHYLIFCTKRGIIKKTLLEAYSR-RT--SGV---IAINLSEDD
SLVSVSLT---NGKAELLVANRNGRAVRFH---VRAIRGMGVKGMTLDDG-DVIGMISIRDQESVLVVSEKGYGKRSKI-DYRITNRGGKGVKTLNITTG
L-LVAVRSVT-EHDLMIINKSGIAIRLRARDLAIIGRATQGVRLINLDKRG-DEIASVCRVI--------------------------------------
------------
>tr|A0A0A2FG19|A0A0A2FG19_9PORP DNA gyrase subunit A OS=Porphyromonas crevioricanis GN=gyrA PE=3 SV=1
-------HATILLFTAKGKCYWLKVYEIPEGAKNAKGRAIQNLLNPDKVTAFIRIKNSHYLMFATKTGMVKKTLLEAYSR-RT--NGV---IAINLNEGD
EVVSVRLT---NGRNQILIANRNGRAVRFD---VRTVRSIGVRGMRLDDG-DVIGMIAIK-EQTVLVVSEHGYGKRSSIEDYRTTNRGGKGVKTMQVTTG
H-LIDIRAVE-DNDLMIINKSGVAIRISVKDIAVIGRATQGVRLINLDKRG-DDIASVCSVI--------------------------------------
------------
>tr|A0A0A2E7S9|A0A0A2E7S9_9PORP DNA gyrase subunit A OS=Porphyromonas macacae GN=gyrA PE=3 SV=1
-------HATLIFFTEQGKCYWLKVYQIPEGSRTGKGRAIQNLLNANRVNAIVWVKNTHYLVFCTKQGLVKKTPLEAYSR-RA--NGV---IAIGLREGD
QVVSVRLT---NGRNELVIANRNGRAIRFS---IRPSRSMGVRGITLDDG-DVIGMVAIK-EETILVISEKGYGKRSHVEDYRVTNRSGKGVKTLNITTG
N-LVDIRSVT-DQGLMIINKSGVTIRLNVEELPVIGRATQGVRLINLEKRD-DEIASVCGVA--------------------------------------
------------
>tr|A0A0A2F8S2|A0A0A2F8S2_9PORP DNA gyrase subunit A OS=Porphyromonas sp. COT-290 OH860 GN=gyrA PE=3 SV=1
-------HATMLLFTQMGRCYWLKVYEIPEGAKNAKGRAIQNLLNPDRVTAFIRIKKSHYLFFATKRGVVKKTLLEAYSR-RT--TGI---IAINLLEGD
ELVGVALT---NGRSEIVLANRNGRAVRFN---VRHTRATGVRGMILDDG-DVIGMLAVK-KESILVVSEHGFGKRSNVEDYRITNRGTKGVKTLNITTG
V-LVAIRSVT-EHDLMIINRSGVTIRVHARDLSIIGRNTQGVRIINLDKRG-DEIASVCRVM--------------------------------------
------------
>tr|A0A0K1RPH3|A0A0K1RPH3_PORGN DNA gyrase subunit A OS=Porphyromonas gingivalis GN=gyrA PE=3 SV=1
-------HATIMLFTAKGRCYWLKVYEIPEGAKNAKGRAIQNLLNPDKVNAFIRIKNSHYLLFCTKRGIIKKTLLEAFSR-RA--NGV---IAIDLRDND
GLVSVRLT---NGKCDMVIANRGGRAIRFH---VRPSRAMGVKGMTLDDG-DVVGMISIK-EETILVVSEKGYGKRSNIDDYRITNRGGKGVKTLNITTG
K-LVDIRAVT-ANDLMIINKSGVAIRVKVADLSIIGRATQGVKLIDLSKRG-DEIASVCSVV--------------------------------------
------------
>tr|A0A0D3VGA9|A0A0D3VGA9_9BACL DNA gyrase subunit A OS=Paenibacillus sp. IHBB 10380 GN=gyrA PE=3 SV=1
-------HHYLLFFTDRGKVYRLKAYEIPELSRTARGTAIINLIQQETVNAVIPVQGEDYLFFATRQGVVKKTPLEDYIN-RK--GGL---IAINLRDDD
ALIGVK-T---DG-QEVIMGTAQGMSIRFSE--VRSMRATGVKGIRLS---EVIGMDVVDKDLDILIVTSKGYGKRTPVSDYRSQSRGGKGIKTINVTNG
P-VIALKVVKE-EDLMIITTSGTLIRTSMEGISTMGRYTQGVKLINTRED--DAVATVCRVD--------------------------------------
------------
>tr|D5WQZ8|D5WQZ8_KYRT2 DNA gyrase subunit A OS=Kyrpidia tusciae (strain DSM 2912 / NBRC 15312 / T2) GN=gyrA PE=3 SV=1
-------HHYLLFFTNKGKVYRLKAYEVPELGRAAKGTPIVNLLNQEKISAVVPIRGGQYLIMATREGTIKKTPLDEFEN-RR--GGL---VAISLREND
ELIAVR-T---DG-RELILGTRSGMAIRFPE--VRSMRAAGVKAVDLQ---GVIDMDVVDPDGDVLVVTNRGFGKRTPITEYRHQSRGGKGIRTLHVTTG
S-VVSLKMVRD-EDVMVITTTGIAIRMHVDEISVQGRNTQGVKLITLKED--EEVSTVAKVV--------------------------------------
------------
>tr|R6V5X3|R6V5X3_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:964 GN=gyrA PE=3 SV=1
-------HDYVLFFTNFGRVYRLKCYEIPES-RTSKGMNIANLLPPEKVTSVIKVPDEKYLIMVTKQGLVKRIKLSAYNTNRK--GGV---VALELNEGD
ELAWVRMT---DGSSQVVVATRLGKAIRFD---VRPMRARGVKALTLL---YVIGMTTVN-DDMILTVSEAGYGRLSNVSDYRLQSRGGKGIINYHTEYG
N-VAAISAVD-NDDIIIISSDGVIIRIEASSIRI-SRPSKGVTVMRVND-E-NKVVTLAVAP--------------------------------------
------------
>tr|J0WSD1|J0WSD1_9CLOT DNA gyrase subunit A OS=Clostridium sp. MSTE9 GN=gyrA PE=3 SV=1
-------HDYVLFFSNLGRVYRLKCYEVPE-SRTSKGINIANLLPSESVTSMVRVP-ESYLVMVTKNGIIKRTVLSAYNTARK--GGV---IAIDLDEGD
SLSWVRRT---DGNREMLVATKKGMSIRFR---VRAMRARGVKAITLK---CVTGLSTIR-GGLVLTVSETGYGRLSPITDYRTQSRGGKGLLNYHVEYG
D-VASIKVVD-DDDVIIISSDGVIIRIHAASIRV-ARPSKGVRVMRVNGVE-NRVVTLARAP--------------------------------------
------------
>tr|R5GFY2|R5GFY2_9PORP DNA gyrase subunit A OS=Porphyromonas sp. CAG:1061 GN=gyrA PE=3 SV=1
-------HATLLFFTEQGRCYWLRVFEIPEGARNSKGRAIQNLLNANRVNAVLRVKNTHYLTFFTKSGLVRKSRLKDFSR-RQ--SGI---IAIKLRDDD
KVVSVMLS---NGKCDFVLGSRKGRAVRFS---LRPLRSMGVRGMRLEDG-ELVGAVCIK-EETILVISENGYGKRSSLEDYPLRNRGGKGVITLKITTG
E-LVSIHSVT-AHDIMIINKSGVAIRTSMKDISVIGRNTQGVKLINLSKRG-DEIASTCRVL--------------------------------------
------------
>tr|A0A0A2DVY1|A0A0A2DVY1_9PORP DNA gyrase subunit A OS=Porphyromonas sp. COT-108 OH1349 GN=gyrA PE=3 SV=1
-------HATMLFFTEKGKCFWLPVYEIPEGSRQAKGRAVQNLLNPDKISACIRVKRSHYITFVTQNGTVRKTSLEAFSR-RA--NGI---IAIKLVEDD
KVVSVLLS---NGDCQFLIASRNGKAVRFH---VRPLRSIGVRGIRLDDG-DVVGAICVK-SESILVVSENGFGKRSVIEDYRQTNRGTKGVLTLKVTTG
K-LVSMKNVT-DNDLMIINKSGIVIRISVDSISMLSRNTQGVKLINLQSNG-DEIASVTVVE--------------------------------------
------------
>tr|A0A0A2EN83|A0A0A2EN83_PORCN DNA gyrase subunit A OS=Porphyromonas cangingivalis GN=gyrA PE=3 SV=1
-------HATMLFFTEKGRCFWLRVFEIPEGTRTSKGRAIQNILNPDRVTTCIRIKNSHYLTFVTRRGTIRKTLLEAFSR-RA--NGI---IAIGLRDED
RVVSVLLS---NGKSEFILASRNGKAIRFH---LRPQRTMGVRGMRLEDG-DVIGAICIK-EESILVVSENGYGKRSQIDDYRITNRGAKGVITLKVTTG
D-LIEIKNVT-EHDIMIINKSGVTIRTHVKDISVQSRNTQGVRLINLERRG-DEIASVCRVQ--------------------------------------
------------
>tr|R5CL61|R5CL61_9FIRM DNA gyrase subunit A OS=Firmicutes bacterium CAG:791 GN=gyrA PE=3 SV=1
-------KDTLLIFTTKGRVYKLKTYKIPEASRTSRGTAIVNLLQAEKVSALIPVQDDKSLFMVTRNGIVKKTRCREFAN-RS--NGI---NAIAIQDGD
ALIEVK-T---CA-DDIIIVTKKGMSVRFHE--VRATRSMGVMGIRLD---NVAGMQLSSQGDSILVVSEKGMGKRSSLEDFRVQNRGGKGIKCYKITTG
D-VVGVKAVND-HEIMMITSAGIIIQIRMNEVPVHGRITSGVKLINLEDG--VKVVKIAKVR--------------------------------------
------------
>tr|A0A0H3K8X7|A0A0H3K8X7_SYNP6 DNA gyrase subunit A OS=Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1) GN=gyrA PE=3 SV=1
-------HDNILFFSDRGVVYNLPAYRIPAASRNARGVPIVQLLPRERITSIVPVSDDEYLVMLTQGGYIKKTALSAFANIRS--NGL---IAIALSEGD
QLRWVRLA---KPEDSILIGSRKGMTIHFRA--LRPLRTRGVRAMSLR---TLISMDVLPAGPWVLVVTAQGLGKRVPVHQFRLQKRAGLGLRAIKF-QD
E-LVSLRIVE-GDELVMISQRSVIIRQASDAIPQQSRAATGVRVQRLDA-D-DVLAAVALVP--------------------------------------
------------
>tr|L8APX4|L8APX4_BACIU DNA gyrase subunit A OS=Bacillus subtilis BEST7613 GN=gyrA PE=3 SV=1
-------HDKVLFFSDRGVVYSLNAYQIPIASRTARGVPIVQMLPKEKITSLVSVSDDTYFIMLTKQGYIKKTALSAFSNIRA--NGL---IAISLVEGD
QLRWVRLA---KAEDSVIIGSQKGMAIHFKA--LRALRTRGVKSMRLR---ALISMDILPSGPWLLGVTMKGFGKRVPIGQFRLQHRAGLGVKAIRF-DD
Q-LVALHVVN-DDELMIVTNRGIIIRQSVNDISPQSRSATGVRVQRLDA-D-DAIAAVALVP--------------------------------------
------------
>tr|Q608R9|Q608R9_METCA DNA gyrase subunit A OS=Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath) GN=gyrA PE=3 SV=1
-------HDTILCFSSSGKVYWLKVYELPVASRTARGRPFVNLLP-ERINAILPIREAHFIFMATASGTVKKVALSEFERPRP--SGK---IAIELRDDD
RLVDVAIT---NGEQDVMLFSSDGKVVCFHETDVRAMRAAGVRGMTLQERK-VIALIIAS-EGTVLNITENGYGKRTRLEEFPRHRRGGQGVIAIQTSNG
A-VVGAALVEDEDEIMLITDAGTLVRTRVSEISVLSRNTQGVTVIRLN-PG-EKVVGMDRIG--------------------------------------
------------
>tr|C7DIB2|C7DIB2_MICA2 DNA gyrase subunit A OS=Candidatus Micrarchaeum acidiphilum ARMAN-2 GN=gyrA PE=3 SV=1
-------KDYLLVITSAGRVYWLKGYVVPEGGRYAQGKAAVNLISEERIEQIINTRSGKNLIFATRRGRIKSTKAELFSRPRA--NGI---RAIKLNEDD
IVVGVCLS---TGGSNVFLATRNGKAIRFME--LRHMRASGVRGIRLK---ELVDVV--VAKKNIITITERGYGKATLLERYRLQRRGGGGVINL--TTG
K-VVRVLDGEQDDNVIIFNSKGLSIRFNANAIRVTGRNASGVRLMKLEA-D-AKVVDAQIVG--------------------------------------
------------
>tr|D5BWP7|D5BWP7_NITHN DNA gyrase subunit A OS=Nitrosococcus halophilus (strain Nc4) GN=gyrA PE=3 SV=1
-------HDTLLCFSSRGKVYWKKVYELPQGTRTARGKPIVNLLP-ERINTVLPIREGKYVFMVTASGVVKKTSLAVFSRPRP--SGI---IALELREGD
QLVGADLT---DGEQEIMLFSSGGKVIRFSEQKVRPMRARGVKGMELPPHR-VIALIIAR-NGTILTATELGYGKRTAIAEYRLQGRGGQGIISIQTTNG
Q-VVGAVQVEEEDEIVLITNRGTLIRTPVCDISLMGRNTQGVKLINLL-EG-ERLVGVERIV--------------------------------------
------------
>tr|S2D9N1|S2D9N1_9BACT DNA gyrase subunit A OS=Indibacter alkaliphilus LW1 GN=gyrA PE=3 SV=1
-------HNYLLIFTDHGKLFWLKTYAIPEGSKTSKGRPIQNLINADKIRSIIQVANNHFLVMVTKQGIIKKTTLEQYSR-RS--NGI---IALNIREDD
QLLRVDMT---NGDSHIIIAAKSGRAIHFH---VRPMRATGVKAIKLSV--DVVGMVCASRDANLLVVSEKGYGKRSPLDEYRITNRGGKGVKAMNVTTG
S-LVAIKEVV-SDDLMIINKSGITIRTPVANLRVMGRATQGVRLIKLSE-N-DQISSVEKIE--------------------------------------
------------
>tr|A0A0P7XRG0|A0A0P7XRG0_9BACT DNA gyrase, A subunit OS=Algoriphagus marincola HL-49 GN=gyrA PE=4 SV=1
-------HNYLLIFTDQGKLFWLKTYAIPEGGKTSKGRPIQNLINSDRIRAIIQVNNNHFLIMVTKKGIIKKTTLEQYSR-RT--NGI---IALNIREDD
QLVNVDMT---NGDQHIVIAAKSGRAIHFH---VRPMRATGVKAITLNV--DVVGMVCASENATLLVVSEKGYGKRSFLEEYRITNRGGKGVKAMNTTTG
A-LVAIKQVV-TDDLMIINKSGITIRISVDGLRIMGRATQGVRLIKISE-G-DEISSVEKIS--------------------------------------
------------
>tr|L0G3A1|L0G3A1_ECHVK DNA gyrase subunit A OS=Echinicola vietnamensis (strain DSM 17526 / LMG 23754 / KMM 6221) GN=gyrA PE=3 SV=1
-------HNYLLIFTDKGKLFWLKTYAIPEGSKTSKGRPIQNLINSDKIRSIIQVTQNNFLVMVTKNGVIKKTTLEQYSR-RS--NGI---IALNIREDD
QLLNVEFT---HGDSHILIAAKSGRAIHFH---VRPMRATGVKAITLSD--DVVGMVCVNREATLLVVSEKGYGKRSAVEEYRITNRGGKGVKAMNVTTG
S-LVAIKSVI-SDDLMIINKSGIIIRTPVSGLRIMGRATQGVRLIKLNE-N-DEISSVAKVE--------------------------------------
------------
>tr|R7ZW75|R7ZW75_9BACT DNA gyrase subunit A OS=Cyclobacteriaceae bacterium AK24 GN=gyrA PE=3 SV=1
-------HNYLLIFTDQGKLFWLKTYAIPEGGKTSKGRPIQNLMNSDKIRSIIQVSNNNYIVMITKNGIIKKTTLEQYSR-RT--NGI---IALNIRDED
QLVNVELT---NGDSHIVIAASSGRAVHFH---VRPMRATGVKAINLEG--YVIGMVCVSRDATLLVVSEKGYGKRSYLSEYRVTNRGGKGVKAMNVTTG
G-LVAIKEVV-SDDLMIINKSGIAIRTPVSGVRVMGRATQGVKLIRLNE-N-DEISSIEKIE--------------------------------------
------------
>tr|G0IWF9|G0IWF9_CYCMS DNA gyrase subunit A OS=Cyclobacterium marinum (strain ATCC 25205 / DSM 745) GN=gyrA PE=3 SV=1
-------HNYLLIFTDQGKLFWLKTYAIPEGSKTSKGRPIQNLINSDRIRSIIQVKNNNNIVMITKKGIIKKTTLEQYSR-RT--NGI---IALNIREDD
QLLNVELT---NGDANIVIASSSGRAVHFH---VRPMRATGVKAINLDE--NVIGMVCVQRDATLLVVTEKGYGKRSFLSEYRITNRGGKGVKAMNITTG
G-LVAIKEVV-TDDLMIINRSGITIRTPAEGIRVMGRATQGVRLIRLNE-N-DEISSVEKIE--------------------------------------
------------
>tr|U5C452|U5C452_9BACT DNA gyrase subunit A OS=Rhodonellum psychrophilum GCM71 = DSM 17998 GN=gyrA PE=3 SV=1
-------HNYLLIFTDLGKLFWLKTYAIPEGAKASRGRPIQNLIQSDKIRSIIQVGNNNFLVMVTKQGIIKKTTLEQYSR-RS--NGI---IALNIREDD
QLIQVEMT---NGDSHILIAAKSGRAIHFH---VRPMRATGVKAIKLSV--DVIGMVCADSETSLLVVSEKGYGKRSPLGEYRITNRGGKGVKAMNVTTG
S-LVAIKQVM-SDDLMIINKSGITIRTPVSELRIMGRATQGVRLIKLGE-N-DEISSVEKIK--------------------------------------
------------
>tr|A3HTG5|A3HTG5_9BACT DNA gyrase subunit A OS=Algoriphagus machipongonensis GN=gyrA PE=3 SV=1
-------HNYLLIFTDQGKLFWLKAYAIPEGNKTSKGRPIQNLINSDRIRSIIQVNNNHFLVMVTKKGVIKKTTLEQYSR-RT--NGI---IALNIREDD
QLVNVKMT---NGDQHIVIAAKSGRAIHFP---VRPMRATGVKAITLTQ--DVIGMVCASETATLLVVSENGYGKRSYLNEYRITNRGGKGVKAMNVTTG
A-LVAIKEVT-ADDLMIINKSGIIIRISMDTLRIMGRATQGVRLIKVGD-S-DQISSVEKIT--------------------------------------
------------
>tr|I5C7N6|I5C7N6_9BACT DNA gyrase subunit A OS=Nitritalea halalkaliphila LW7 GN=gyrA PE=3 SV=1
-------HNYLLIFTDLGKLFWLKAYAIPEGSKTAKGRPIQNLINADKIRSIIQVAKNNFLIMVTKEGVIKKTSLELYAR-RT--NGI---IALNIREGD
QLIRVEKT---NGDSHVIIAAKSGRAIHFH---VRPMRATGVKAISLQE--DVIGMVCAEREATLLVVSEKGYGKRTLLDAYRITNRGGKGVKAMSVTTG
N-LVAIKEVV-SDDLMIINKSGITIRTPVSDLRVMGRATQGVRLIKLSE-T-DEISSVEKIT--------------------------------------
------------
>tr|A0A0K6IXK1|A0A0K6IXK1_9PROT DNA gyrase subunit A OS=Tepidiphilus thermophilus GN=gyrA PE=3 SV=1
-------HDWVLCFSSRGRVYWLRVFELPEGARGARGKPIVNLVP-ERIQAVLPVR-AHYVFFATASGVVKKTALSAFANPRK--AGI---VALSLDDGD
RLIGVDLT---DGTCDVMLFSDAGKAVRFAE-DVRPMRARGVRGMALE--DGVVSMLVVRDSGSVLTATEAGYGKRTPVAEFTRHGRGTKGMIAIQTSNG
R-LVAACLVQPGDEIILISQNGVLIRTSVDDIREMGRSTQGVTLMALD-DG-DRLVTVVKVA--------------------------------------
------------
>tr|F8A8K9|F8A8K9_THEID DNA gyrase subunit A OS=Thermodesulfatator indicus (strain DSM 15286 / JCM 11887 / CIR29812) GN=gyrA PE=3 SV=1
-------HDYFLCFTNKGKLYWLKVYDIPQAGRTAKGTSLRNLLPQEKIATILPVK-DQFVFFATKKGLVKKTSLSAFSH-RN--TGI---VAAVVKDGD
ELMAAG-T---DG-KEILLVTRKGQSIRFSE--VRPMRAAGVKGIELT--DEVVSLEILDPEASLLTVTELGYGKRTSLKEYRLQSRGGKGIIAMKLTTG
K-LVGCARVCD-DEIMLASTAGKIIRLRVKDIPVQGRATQGVRLFMMAG-G-EKIVSLAKLA--------------------------------------
------------
>tr|A8DJD0|A8DJD0_9BACT DNA gyrase subunit A OS=Chloracidobacterium thermophilum GN=gyrA PE=3 SV=1
-------HSFLLIFTAKGQVYKVRVHEIPDAATSGRGKAIVNLIEEERIAGTIPVRSGQFIVFATRRGIIKKTELSEYANIRS--NGI---VAMGIAEDD
ELVAVQ-S---DGSRHILISTFGGQAICFKE--VRPTRAQGIIGIRLR---DVTGMSVVG-ED-ILSLSELGLSKRTPITEYPVHHRGGQGVATM--TTG
G-VIKTLPVHEDDEFMVITQQGQVARLKVSDVRQTKRLAQGVKVIALAE-G-DRVVDACLVE--------------------------------------
------------
>tr|E6W0A6|E6W0A6_DESIS DNA gyrase subunit A OS=Desulfurispirillum indicum (strain ATCC BAA-1389 / S5) GN=gyrA PE=3 SV=1
-------HEYLMIFTDRGRVYWIKAYNIPEQGRNSRGKAIVNFVDKEKISTVFPVR--KFLLFITKNGIAKKTPLSEYAN-RK--KGV---NAINLDDDD
ELIQVM-T---NG-NSVMVTTRFGASIHFEE--VRAVRSRGVKGITLV--DYVVSAETISKPSYILTVTDLGYGKRTITDEYRLQSRGGKGNLTIKTTNG
L-VVRGLQVVG-DEILLLSKEGKIIRLDSKHIRITGRNTQGVKLVDLSR-D-DRIISVAVAK--------------------------------------
------------
>tr|E6Q9V1|E6Q9V1_9ZZZZ DNA gyrase subunit A OS=mine drainage metagenome GN=gyrA PE=3 SV=1
-------HAYCLFFSNLGKVFWQKVYQLPQAGRGAKGKPIVNMLS-ERITAVLPVREGQFVCMVTSLGVVKKTPVMEYSRPRS--QGI---NAINLDPGD
RLVAVGLS---DGQREFMLFTRHGMAVRFPEAKVRAMRARGVRGISLEE--DVISAQWVDSSQVILTTTANGYGKLTKVDEYRRTNRGGKGVIAIQTNNG
D-VVGALAVTERDELMLVSDHGTLIRIAVNSIRRTGRNAQGVRLINLG-EG-EQLAGLALIA--------------------------------------
------------
>tr|F2IA69|F2IA69_FLUTR DNA gyrase subunit A OS=Fluviicola taffensis (strain DSM 16823 / RW262 / RW262) GN=gyrA PE=3 SV=1
-------HNYLLIFTEKGRCFWMRVFEVPEGNKTAKGRAIQNLLNQDKIKAYVKVKQNNFIVMCTKEGIIKKTSLEAYSR-RA--NGI---NAITIREND
ELLEARLT---DGTNEMVLATKAGRAIRFN---VRPMRASGVRAVTLQDT-DVVGMICVKDTETIMVVSEKGYGKRSFLNVYRITNRGGKGVKTINITTG
P-LLAIKTVA-EDDLMIITKAGVTIRMHIDGIRVMGRAAQGVRLINLKG-T-AAIAAVARVP--------------------------------------
------------
>tr|A0A0P7BYK1|A0A0P7BYK1_9BACT DNA gyrase subunit A OS=Leadbetterella sp. JN14-9 GN=AFM12_02970 PE=4 SV=1
-------HNYLLFFTEKGKLFWLRVFEVPEGNKTSKGRAIQNLINSDSIRAVLNVKNNNFIIMCTKNGVVKKTLLEAYSR-RV--NGI---IAININEGD
QLLDVALT---NGDNHIIIAASEGKAVRFH---IRAMRATGVRGIKLS---DAIGMVCVNRDAQLMVVSENGYGKRSDIEEYRITSRGAKGVKALNITTG
K-LVAIKEVT-EDDLMIITIKGILIRMSVSDLRVMGRATQGVRLIKLNN-N-DGIASVTRIV--------------------------------------
------------
>tr|A0A0C1RB75|A0A0C1RB75_9CYAN DNA gyrase subunit A OS=Tolypothrix bouteillei VB521301 GN=gyrA PE=3 SV=1
-------HDSVLFFSERGVVYCLKTYQIPVSSRTSRGTPIVQLLPKEKITSIVPVTSDEYLVMLTNGGYIKKTELAAFSNIRA--NGL---IAISLEEGD
QLRWVRRA---RVEDSVIIGSRRGMAIHFRC--LRPLRTRGVKAMKLR---DLVGMDILPAGPWVLVITMGGYGKRVPVSQFRLQKRAGQGIMATKFRKD
Q-LATLHIVNDDAEIMMVTSRGIIIRQAVNAISIQSRSATGVRVQRLDE-D-DVITGVAIVP--------------------------------------
------------
>tr|A0A0C1TDK5|A0A0C1TDK5_9CYAN DNA gyrase subunit A OS=Scytonema millei VB511283 GN=gyrA PE=3 SV=1
-------HDSVLFFSDRGVVYSLKAYQIPVGSRTSRGVPIVQMLPKERITSIVPVSSDEYLVMLTKGGYIKKTELAAFTNIRA--NGL---IAISLEEGD
QLRWVRRA---RVEDSIIIGSRFGMAIHFRT--LRPLRTRGVKAMKLK---DLIGMDIIASGPWVLIVTMAGYGKRVPVSQFKLYNRATKGKIATKFNKD
K-LAALMVVN-GDELMLITTRGIIIRQSTDAIPRQSRSATGVRVQRLDE-D-DAIAAVALVP--------------------------------------
------------
>tr|K9XAV0|K9XAV0_9CHRO DNA gyrase subunit A OS=Gloeocapsa sp. PCC 7428 GN=gyrA PE=3 SV=1
-------HDSVLFFSDRGVVYCLKAYQIPLGSRTSRGTPMVQMLPKEKITSVVPVSSDEYLVMLTRGGYIKKTELSAFSNIRA--NGL---IAISLEEGD
QLRWVRRA---RVEDSIIIGSRYGMAIHFRT--LRPLRTRGVRAMKLR---DLIGMDILPSGPWVLIVTMGGYGKRVPVTQFKLYNRATKGKIATKFRKD
Q-LAALHIVN-NDELMIVTSRGIIIRQAVKAISPQSRSATGVRVQRLDE-D-DAIAAVALVP--------------------------------------
------------
>tr|K9B0Y3|K9B0Y3_9MICO DNA gyrase subunit A OS=Brevibacterium casei S18 GN=gyrA PE=3 SV=1
-------HNWLLFFTNTGRVYRAKAYEIPEGSRDAKGQHVANLLAPETIAKVLSIRAE-FLILATKSGVVKKTRLSEYDS-RT--GGV---IAINLREPD
ELVSAR-----SSEDHLLLISRKGMSIRFAD--IRPLRTGGVTGMKFK-D-DLLTMDVVQPGTYVFVVTEGGYAKRTPVDEYRVQGRGGLGIRVAKITRG
D-LVGGLIVDG-EEVLVVMERGKVVRSNIDEVPA-GRNTMGVVFAKPGK-N-DRIIAVTRGP--------------------------------------
------------
>tr|A8UA59|A8UA59_9LACT DNA gyrase subunit A OS=Carnobacterium sp. AT7 GN=gyrA PE=3 SV=1
-------HDTLLFFTNNGKVYRSKGYEIPEYGRTAKGIPVINLLGDETVQAVINVRDGLYLFFTTRLGTVKRTDVKAFSN-RS--NGL---KAIVLKEND
ELMSVS-T---NG-ENIIIGTHMGYAVSFHE--VRNMRAGGVRGIRLR---NVIGVDLLKEDSEVLIITEKGYGKRTKASEYAIKGRGGKGIKTANITNG
N-LAGLTTVKD-EDIMLITNTGVIIRFNVSAVSQTGRATLGVRVIRVAEE--VKVSTMAKVD--------------------------------------
------------
>tr|M0NIV2|M0NIV2_9EURY DNA gyrase subunit A OS=Halorubrum kocurii JCM 14978 GN=gyrA PE=3 SV=1
-------HDYLLVFTNRGQIYELKTYEIPEMSRTARGKSAVNLLDDEEIEAVVN--DEEFLTMVTRDGYIKRTAVDEFGNIRS--TGI---RAIRLEDGD
ELVDVE-T---DGDTDIVIGSRNGMAIRFDE--ARAMRARGVIGIDLR---DVAGVAAIDDHNWVLSVTENGYGKRSDLDEYRQQSRNGKGLIDI--GNG
E-AVAIEAVTYGDHLLAMSDDGQIMRTRVEEISTVSRNTKGVIVMNLDP-D-DAVASVDIVP--------------------------------------
------------
>tr|M0M3Y7|M0M3Y7_HALMO DNA gyrase subunit A OS=Halococcus morrhuae DSM 1307 GN=gyrA PE=3 SV=1
-------HDYLLTFTNQGYVYRLKVYEVPEMGRTARGKSAINLV-DEAITAVVATD-EECLTMVTRDGYVKRTCASEFENIHS--GGL---IATRLEDGD
ELVDVA-T---DDDGDLLIGTQRGMAIRFPK--AREMRARGVNGVDLQ---DVAGVVTATDDADLLTVTENGYGKRTPMSEYSTQSRYGKGLKDI--NNG
R-VTAIESATADDDLVAMSDTGQIMRTPVGDISTVGRNTMGVTIMALED-G-DGIACIDVLE--------------------------------------
------------
>tr|V4XTA8|V4XTA8_9ARCH DNA gyrase subunit A OS=uncultured archaeon A07HR67 GN=gyrA PE=3 SV=1
-------HDYLLVFTNHGQIYRLKTYEIPELSRTARGKSAVNLLDDEEIEAVVN--GEEFLTMVTRDGYIKRTAVDEFENIRS--TGI---RAIRLDDDD
ELADVE-T---DGEAHIVIGSRDGMAIRFEE--VRPMRARGVIGIDLR---DVAGVAAVDIHDWVLTVTQNGYGKRSDLAEYRPQSRNGMGLVDI--GNG
E-TVAIEAVSYGDHLVAMSADGQIVRTRVEEVSTVSRNTMGVIVMDLDP-D-DEVASVDIVP--------------------------------------
------------
>tr|U1QK87|U1QK87_9EURY DNA gyrase subunit A OS=Halonotius sp. J07HN4 GN=gyrA PE=3 SV=1
-------HDYLLCFTTHGQIYKLRGFQIPEMSRTARGKSAVNILDDEELTAVVNTDADRYLTMVTGNGYIKRTAVDAFQNIHR--SGI---RAIRLEDDD
ELVDVEVT---DGDRTLVMTTADGMSIRFDE--VRAMRARGVCGIDLQ---TVAGVAAVDAHSWVLTVTKNGYGKRSDIDEYRVQSRNGKGLIDI--GNG
P-VCGMETVGPGDHLLVMSQSGQIMRTPITDVSAVGRNTMGVIVMDLDD-T-DRVSCLDVIP--------------------------------------
------------
>tr|U1Q3U1|U1Q3U1_9EURY DNA gyrase subunit A OS=Halonotius sp. J07HN6 GN=gyrA PE=3 SV=1
-------HDYLLCFTNHGQIYKLRGFQIPEMSRTARGKSAVNLLDDEELTAVVNTDADRYLTMVTRDGFIKRTGVDEFQNIHK--SGI---RAIRLEDGD
ALVDVEVT---DGDRSLVVTTTGGMSIRFAE--VRAMRARGVRGIDLQ---TVAGVAAVDTHSWVLTVTGNGYGKRSDIDDYRVQSRNGKGLIDI--DNG
S-VCAMETVGPGDHLVVMSKSGQIMRTPVQDISTVGRNTKGVIVMDLDA-D-DSVACLDVIP--------------------------------------
------------
>tr|G8R2P3|G8R2P3_OWEHD DNA gyrase subunit A OS=Owenweeksia hongkongensis (strain DSM 17368 / JCM 12287 / NRRL B-23963) GN=gyrA PE=3 SV=1
-------HQYMLFFTEWGRCYWLRVYEIPEGSKASKGRAIQNLINQDKVRAFINTKNSHFIVMVTEKGVIKKTPLEAYSR-RV--NGI---NAITVREGD
LLLEAKLT---TGKDEILMAKKSGKAIRFN---VRSMRASGVRGVTLEE--DVIGMVTVPHEPTILVVTEKGYGKRTLLE-YRVTNRGGKGVKTLNTTTG
N-LVAIKAVS-EEDLVIINKSGVMIRTGVAELRVMGRATQGVRIINLKK-K-DAIASVAKVP--------------------------------------
------------
>tr|L9V9C9|L9V9C9_NATMM DNA gyrase subunit A OS=Natrialba magadii (strain ATCC 43099 / DSM 3394 / NCIMB 2190 / MS3) GN=gyrA PE=3 SV=1
-------HDYLLCFTNQGKVYQLKTYEIPEMGRTARGKSAVNIL-PEDITAIVDTD-DEFVTMATRHGYVKRTAGSEFDNIRS--TGI---IAADLQEGD
ELVDVE-T---DGTKDLVIASENGMTIRFDE--VRAMRARGVNGIDLQ---DVAGLVATDEEQDLLTVTQNGYGKRTPLSEYRTQSRYGKGLIDI--GNG
P-VTTAKAVSADDQLVMMSERGQIVRTRVDEISTVGRNTMGVIVMDVDD-G-DAVASVDVVP--------------------------------------
------------
>tr|D8J640|D8J640_HALJB DNA gyrase subunit A OS=Halalkalicoccus jeotgali (strain DSM 18796 / CECT 7217 / JCM 14584 / KCTC 4019 / B3) GN=gyrA PE=3 SV=1
-------HDYLLCFTNHGKAYQIRGFDVPEMSRTARGKSAVNIL-PEELTAVVNTD-EEFLTMVTENGYVKRTEASAFERVRS--SGL---IAASLEEGD
RLVDVT-T---DGSADLLIATRNGMAIRFPE--ARAMRARGVNGIKLQ---DVVGLVTADESRSLLTITENGYGKRTPFSEYRTQSRYGKGLIDI--GNG
P-VAAVESVSEDDDLVVMSDDAQIMRIHAADVSRVGRNTKGVIVMRLAG-D-DRVASVDVIP--------------------------------------
------------
>tr|L0ICV0|L0ICV0_HALRX DNA gyrase subunit A OS=Halovivax ruber (strain DSM 18193 / JCM 13892 / XH-70) GN=gyrA PE=3 SV=1
-------HDYLLCFTNQGQVYQLKAYEIPEMGRTARGKSAVNIL-PEELTAIVDTD-DEFVTMVTRHGYVKRTRGDEFDNILT--TGI---IAASLEDGD
ELVDVE-T---DGTNDLVIGTEQGMTIRFDE--ARAMRARGVNGIKLE---DVAGLVATTEERALLTVTENGYGKRTLLSEYRTQSRYGKGLIDI--ENG
P-ATALKAVAPDDQLVIMSERGQIMRTRASEISTVSRNTMGVTVMDVEA-G-DAVASVDVLS--------------------------------------
------------
>tr|C7NP30|C7NP30_HALUD DNA gyrase subunit A OS=Halorhabdus utahensis (strain DSM 12940 / JCM 11049 / AX-2) GN=gyrA PE=3 SV=1
-------HDYLLAFTNHGQVYRLRTYEIPEMSRTARGKSAVNLI-DEEITAVVSMD-DECITMATRQGYVKRTCCSEFENILS--TGI---IAAKLEDGD
ELVDAV-T---DGESDLVIATEDGMTIRFDE--ARQMRARGVRGIDLR---DVAGVVATDEERALLTVTERGYGKRTPLSEYRTQSRYGKGLIDI--GNG
G-VTAVNAVAEDDHVIVMSATGQIMRCPVEDVSTVGRNTMGVTIMDVAA-D-DTVASVDVIP--------------------------------------
------------
>tr|L9W2S5|L9W2S5_9EURY DNA gyrase subunit A OS=Natronorubrum bangense JCM 10635 GN=gyrA PE=3 SV=1
-------HDYLLCFTNQGKVYQLKTYEIPEMGRTARGKSAVNIL-TEDITAIVDTD-GEFVTMATRNGYVKRTAGSEFDNIRS--TGI---IAADLEDGD
ELVDVE-T---DGSQDLVIATEGGMTIRFDE--VRSMRARGVNGIKLE---DVAGLVATDEERALLTVTQNGYGKRTRLSAYRTQSRYGKGLIDI--GNG
P-VTAVKAVADDDELVMMSERGQIVRTRVDDISTVGRNTMGVIVMDVEA-G-DAVASVDEIP--------------------------------------
------------
>tr|L9WXW4|L9WXW4_9EURY DNA gyrase subunit A OS=Natronococcus amylolyticus DSM 10524 GN=gyrA PE=3 SV=1
-------HDFLLCFTNQGKVYQLKTYEIPEMGRTARGKSAVNIL-AEDITAIVDTD-DEYVTMVTRNGYVKRTAGEEFDNIRS--TGI---IAADLEEDD
ELVDVE-T---DGSQDLVIATEGGMTIRFDE--VRAMRARGVNGIKLT---DVAGLVATDEERALLTVTRNGYGKRTPLSEYRTQSRYGKGLIDI--DNG
H-VTTVKAVDADDHLVMMSERGQIVRTRVDEVSTVGRNTMGVTVMDVDD-G-DAVASVDVLP--------------------------------------
------------
>tr|L0AC50|L0AC50_NATGS DNA gyrase subunit A OS=Natronobacterium gregoryi (strain ATCC 43098 / CCM 3738 / NCIMB 2189 / SP2) GN=gyrA PE=3 SV=1
-------HDYLLCFTNQGNVYQLKTYEIPEMGRTARGKSAVNIL-DEDITAIVDTD-DEFVTMATRNGYVKRTASEEFDNIRS--TGI---IAADLEEGD
ELVDVE-T---DGSQDLVIATEGGMTIRFAE--VRAMRARGVNGIKLQ---DVAGLVAANGGQALLTVTRNGYGKRTPIEEYSTQSRYGKGLIDI--ENG
P-VTAIKAVSEDDHLVLMSEDGQIVRTRVDEVSTVGRNTMGVIVMQVEG-D-DAVASVDEIP--------------------------------------
------------
>tr|W0JRU3|W0JRU3_9EURY DNA gyrase subunit A OS=Halostagnicola larsenii XH-48 GN=gyrA PE=3 SV=1
-------HDYLLCFTNHGQVYQLKTYEIPEMGRTARGKSAVNIL-DEEITAVVDTD-DECVTMVTKNGYVKRTAGEEFDNILT--TGI---IAASLEESD
ELVDVE-T---DGTTDLVIATERGMTIRFDE--VREMRARGVNGIKLQ---DVAGLVAMDQDRSLLTVTQNGYGKRTLLSEYSKQSRYGKGLIDI--NNG
P-VTAVKAVTEDDHLVAMSERGQIMRTRAGEISTVGRNTMGVTIMDVEA-D-DAVASVDVIP--------------------------------------
------------
>tr|A0A0R2LH47|A0A0R2LH47_9LACO DNA gyrase subunit A OS=Lactobacillus pobuzihii GN=IV66_GL001935 PE=4 SV=1
-------HDELLFFTNTGKVYSSKGYQIPEYGRSAKGIPVINMLNAEKIATVITVPDDKFLFFTTKNGVVKRTAVSEFLN-RK--NGL---KAITLREGD
ELIGVA-T---DG-QNMIIGTHGGYAVSFSE--VRSMRAAGVRGIRLD---NVIGADILGPNSNVFVISEQGYGKQTPASEYAIRGRGGKGVKTVNVTNG
P-LVGLTTVFD-EDIMVITNKGVLIRFDVANVSTTGRSTLGVHLINLEEG--SFVSTMAKVA--------------------------------------
------------
>tr|A0A0R1ZDK5|A0A0R1ZDK5_9LACO Dna gyrase subunit a OS=Lactobacillus aviarius subsp. araffinosus DSM 20653 GN=FC64_GL000181 PE=4 SV=1
-------HDRLLFFTNLGKVYSMKGYEIPEYGRSAKGIPVINLLNDEKIATVINIPHAKYLFFTTKEGTVKRTPVEDFEN-RK--NGL---KAINLHDGD
ELINVS-T---DG-QNMIIGTHLGYAVSFNE--VRSMRAAGVRGIRLR---NVIGSDILVPGSDVFVISEKGYGKRTPVSEYPIKGRGGKGIKTSNITNG
P-LAGLTIVND-EDIMVITNKGVLIRFNVADVSQTGRSTLGVHLINLEDD--STVSTVAKVD--------------------------------------
------------
>tr|A0A0B8T6G8|A0A0B8T6G8_9SPHI DNA gyrase subunit A OS=Sphingobacterium sp. ACCC 05744 GN=gyrA PE=3 SV=1
-------HNYLLLFTDKGHCFWLRAFEIPEGSRTSRGRALQNIINKEKIKAFIKIIENNFIIMCTKKGTIKKTSLEAYSR-RA--NGI---NAININEGD
ELLEACLT---TGGSEIVMALRSGRAIRFN---VRPMRATGVRGITLAE--DVVGMIAVDSDTTVLVVSEKGYGKRTDVEDYRVTNRGGKGVKTINVTTG
E-LVAIKGVT-ADDLMMINKSGIVIRIGVETLRVMGRATQGVRLITLKD-T-DAIASITKVA--------------------------------------
------------
>tr|A0A0N8W5K5|A0A0N8W5K5_9SPHI DNA gyrase subunit A OS=Pedobacter sp. Hv1 GN=AQF98_09800 PE=4 SV=1
-------HNYMLFFTEAGRCFWLRVYEIPEGSRLSKGRALQNIINKEKVKAYIKVVENNFIIMCTKKGTIKKTSLEAYSR-RV--NGI---NAININEGD
QLLEASLT---TGNSEIVMALRSGRAIRFN---VRPMRATGVRGVTLAD--DVVGMIAINDEATVLVVSEKGYGKRTDIDDYRVTNRGGKGVKTINVTTG
A-LVAIKNVT-ADDLMIINKSGIVIRIVVSELRVMGRATQGVRLITLKG-N-DEIASVAKIE--------------------------------------
------------
>tr|Q7VRW9|Q7VRW9_BLOFL DNA gyrase subunit A OS=Blochmannia floridanus GN=gyrA PE=3 SV=1
-------HDTVLLFSNYGRIYWMKVYRLPKANKGSRGRPIINLLP-ERITVILPVQTGHQVFMATSSGFVKKTALMEFSRPRN--VGI---IALNLNNGD
ELIGADIT---NGDNEVMLFTAYGKVVRFQETQVRSMRASGVRGVHLL--QGVVSLIIPKD-SSILTVTENGFGKRTNQSEYPLKSRAIQGVISIKVTNG
N-VVGAVQVDQGDQIMIVTDSGRLVRIRVSEVNIIKRNTQGVMLIRTA-CD-EHVVGLQRVV--------------------------------------
------------
>tr|L0MX04|L0MX04_9ENTR DNA gyrase subunit A OS=Candidatus Blochmannia chromaiodes str. 640 GN=gyrA PE=3 SV=1
-------HDTVLLFSNYGRIYWMKVYRLPAASRGSRGKPIINLLP-ERITAILPIQTGHQVFMATSSGVVKKTPLTEFSRPRN--VGI---IALNLNDGD
ELIGADVT---DGSNEVMLFTAYGKVVRFKETQVRSVRAIGVKGIHLL--QGVVSLIIPKD-SSILTVTRNGFGKRTNQSEYPIKSRATQGVISIKVTNG
H-VIGAVQVNQSDQIVMITDLGRLVRTRVSEVNIIRRNTQGVMLIRTA-CD-ECVVGLQCVV--------------------------------------
------------
>tr|A0A0E3Y7G8|A0A0E3Y7G8_9ENTR DNA gyrase subunit A OS=Blochmannia endosymbiont of Polyrhachis (Hedomyrma) turneri GN=gyrA PE=3 SV=1
-------HDTILLFSNYGRIYWMKVYRLPAAKHISRGRPIVNLLP-ERITAILPIRIGCQVFMATSSGLVKKTSLTEFCRPRN--MGI---IALNLNKGD
ELIGADIT---YGDNEVMLFSKYGKVVRFQENQVRSVRAIGVRGMNLL--NGVVSLIIPRG-SSILTVTRHGYGKRTNKIEYPVRSRGILGVIAIKVNNG
N-VVGSIQVDDDDEIMMITDCGRLVRIRASEINIFSRNTQGVLLIRTA-NN-ERLVSLQRVV--------------------------------------
------------
>tr|E8Q739|E8Q739_BLOVB DNA gyrase subunit A OS=Blochmannia vafer (strain BVAF) GN=gyrA PE=3 SV=1
-------HDTVLLFSNYGRIYWMKVYRLPEVKRSSRGRPIINLLP-ERITTILPIQKGHQVFMATSSGFVKKTALMEFSRPRN--VGI---IALNLNVGD
ELIGADVT---DGNNEVMLFTAYGKVVRFKETQVRSMRAVGVKGIHLL--QGVVSLIIPKN-SSILTITKNGFGKRTDQSEYPLKSRSTKGVISIKVTNG
N-VVGAVQVSHDDQIMIITDAGRLVRIRVSEVNIIKRNTKGVMLIRTA-CD-EHVVGLQRVV--------------------------------------
------------
>tr|A0A0M4NSY9|A0A0M4NSY9_9GAMM DNA gyrase subunit A OS=Candidatus Thioglobus sp. EF1 GN=gyrA PE=3 SV=1
-------HDTVLCFSSAGKVHWLKVYELPMASRTAKGKPIINLLP-EVINAILPVSDDQFVFMVTSSGTCKKTSLTNFARPRK--GGI---IAIELRDGD
KLVGVEIT---SGENDIMLFSANGKSIRFKEADVRAVRAIGVRGMKLVN--EIVSAIVADESSPILTATEKGYGKRTELEEYRSQARGGSGVISIKTSNG
K-VVGAIQVTDEDEMMLISNKGTLVRARAADVSVIGRNTQGVTLINIS-KG-EKLVSVAKIA--------------------------------------
------------
>tr|A5CXA3|A5CXA3_VESOH DNA gyrase subunit A OS=Vesicomyosocius okutanii subsp. Calyptogena okutanii (strain HA) GN=gyrA PE=3 SV=1
-------HDIVLCFSSFGKVYWLKVYDLPMASRISRGKPIINLLP-EIINAILPILENHFVFMATSSGTCKKTALTNFSKPRK--GGI---IAIELRNND
QLIGVEIT---SGEHDIMLFSANGKSIRFKESDVRIVRAIGVRGIKLVD--DVVSLIVTNQDSPVLTATEKGFGKRTHLNEYRVQSRGGSGVISIKTSNG
K-IIGAIQVTNEDEMMLISNKGILVRARAADVSIIGRNTQGVILINIS-KD-EKLVSIAKVV--------------------------------------
------------
>tr|A1AVX7|A1AVX7_RUTMC DNA gyrase subunit A OS=Ruthia magnifica subsp. Calyptogena magnifica GN=gyrA PE=3 SV=1
-------HDTVLCFSSLGKVYWLKVYELPMASRIARGKPIVNLLP-EIINAILTVSENHFVFMVTSSGTCKKTVLTNFSKPRK--GGI---IAIELKDND
QLIGVEIT---SGEHDIMLFSANGKSIRFKESDVRVVRAIGVRGIKLAN--DVVSLIVVNQDNPILTTTEKGFGKRTRLNEYRSQARGGLGVISIKTSNG
K-VVGAIQITDEDEMMLISNKGTLVRARAVDVSIIGRNTQGVTLINII-KG-EKLVSIAKIA--------------------------------------
------------
>tr|A0A0M4LQC2|A0A0M4LQC2_9GAMM DNA gyrase subunit A OS=Candidatus Thioglobus singularis PS1 GN=gyrA PE=3 SV=1
-------HDTVLCFSSTGKVHWLKVYELPMASRISRGKPIINLLP-ESINAILPVKNDQFVFMVTSSGTCKKTSLQNFSRPRK--GGI---IAIELRDDD
KLVGVEIT---AGEHDILLFSSAGKSIRFKESDVRSVRAIGVRGIRLSD--DVVSLIVAESDDPILTATEKGYGKRTQLDEYRTQARGGSGVISIKTSNG
Q-VVGAIQVTDEDEMMLISDKGTLVRARAADVSIIGRNTQGVTLINIA-DD-EALVSVAKIA--------------------------------------
------------
>tr|A0A0D6AM29|A0A0D6AM29_9CHRO DNA gyrase subunit A OS=Geminocystis sp. NIES-3709 GN=gyrA PE=3 SV=1
-------HDRVLFFSDKGVVYGLSAYQIPSSSRTARGVPIVQLLPSEKITSVIPVSDHEYLVMLTKKGFIKKTALSAFGNIRS--NGL---IAISLEDND
ELRWVRLA---TEDDSVLIGSRRGMAIHFHA--LRPLRAKGVKSMKLR---QIISMDILPSAPWALAVTTSGYGKRVPVSQFRLQRRAGIGVKAIRF-KE
E-LAALHIVN-DDEFMIITTRGIIIRCDVNAVSLQSRNASGVRVQKLDS-D-DAIAAIALVP--------------------------------------
------------
>tr|K9Z2X7|K9Z2X7_CYAAP DNA gyrase subunit A OS=Cyanobacterium aponinum (strain PCC 10605) GN=gyrA PE=3 SV=1
-------HDRILFFSDKGVVYGLNAYQLPALSRNARGVPIVQMLPSEKITSMIAVSDHEYLVMLTQKGLIKKTALSAFANIRS--NGL---IAISLGEGD
ELRWVRLA---TEDDSILIGSRQGMAIHFHA--LRPLRAKGVKSMKLR---EIISMDILPSAPWALAVTTSGFGKRVPVSQFRLQRRAGMGLKAIRF-SD
A-LAALRIVN-EDEFMIITTRGIIIRCDVNAVSLQSRQASGVRVQKLDS-E-DAIAAIALVP--------------------------------------
------------
>tr|K9YRM2|K9YRM2_CYASC DNA gyrase subunit A OS=Cyanobacterium stanieri (strain ATCC 29140 / PCC 7202) GN=gyrA PE=3 SV=1
-------HDTILFFSDRGVVYALNAYQIPSSSRNARGMPIIQMLPSEKITSILAVSDHEYLVMLTRNGFIKKTALSAFGNIRS--NGL---IAISLAEGD
ELRWVRLA---TADDSILIGSRRGMAIHFHA--LRPLRAKGVKSMKLR---QLISMDIIPSAPWALAVTTSGYGKRVPVSQFRLQRRAGLGLKAIRF-NE
E-LAALHIVN-DDEFMIITARGIIIRCDVNAVSLQSRNASGVRVQKLDD-D-DAIAAVALVP--------------------------------------
------------
>tr|A0A0Q2X9E9|A0A0Q2X9E9_CAMJU DNA gyrase subunit A OS=Campylobacter jejuni CVM 41964 GN=Y876_00220 PE=4 SV=1
-------HDTLMFVTDRGQLYWLKVYKIPEGSRTAKGKAVVNLINAEKIMAIIPTTESKSLCFFTKNGIVKRTNLSEYQNIRS--VGV---RAINLDEND
ELVTAIVQRDGGEGKMLFAVTKKGMCIKFP---VREIRSRGVTAIKFKK--DLVGAVVIENEQEILSISAKGIGKRTNAGEYRLQSRGGKGVICMKLTTK
D-LIS-VVVD-TMDLMALTSSGKMIRVDMQSIRKAGRNTSGVIVVNVE-----EVVSIAKCP--------------------------------------
------------
>tr|A0A0F9K7J8|A0A0F9K7J8_9ZZZZ Uncharacterized protein (Fragment) OS=marine sediment metagenome GN=LCGC14_1363040 PE=4 SV=1
-------HDTLLCFSSTGKVYWKKVYELPQGGRAARGKPIVNILPEENINAILAVRADQYIFMVTASGTVKKTPLEAYSRPRA--NGI---IAVDLKDDD
QLISVALT---DGQSDIMLFSSNGKVIRFPETDVRSMRSRGVRGMRLPEVD-IISMIIANPEGAILTATEFGFGKRTDLEQYRVQGRGGSGIISIQTSNG
N-VVGAVQVQPEHQIMLITNGGTLVRTPVKDVSIVGRNTQGVKLINLT-KK-EKLVGLERVL--------------------------------------
------------
>tr|A0A091G0Z1|A0A091G0Z1_9DELT DNA gyrase subunit A OS=Smithella sp. SCADC GN=gyrA PE=3 SV=1
-------HHYLLVFTSAGKVHWLKVYQIPQAGRAAKGKAMINLVNPESVRATLPVK-DKFIVMVTKKGTIKKTELAAYAN-RS--GGI---IAISIDEGD
ELVDVQ-T---MG-QDIFIASRLGMAIRFKE--VRDMRARGVRGINLD--DDVIGMDIPAQNTFMLTVSENGFGKCTPIDEYRVQTRGGKGTINLKTVVG
N-VSGVLQVIE-DNVMLISNAGKVIRLKVQEIPVNHRVTQGVKLIELDP-E-EKLVGVARTT--------------------------------------
------------
>tr|A0A091AFW7|A0A091AFW7_9DELT DNA gyrase subunit A OS=Smithella sp. F21 GN=gyrA PE=3 SV=1
-------HHYLLVFTNMGKVYWLKVYQIPQAGRAAKGKAMVNLVNPEKVSATLPVK-DKFIIMVTKKGIVKKTDLAAYSN-RA--GGI---IAISIDEGD
ELVDVQ-T---MG-QDVFLGTRLGMAIRFNE--VRDTRARGVRGINLD--DDVIGVEIPAQGTFMLTISENGFGKCTPIDEYRVQTRGGKGTINLKTVIG
N-VSGVLQVQE-ENIMLISNAGKVIRLKVQEVPINHRVTQGVKLIDLEP-E-EKLVGVARTT--------------------------------------
------------
>tr|A0A0E2Z5Z8|A0A0E2Z5Z8_9GAMM DNA gyrase subunit A OS=Nitrosococcus oceani C-27 GN=gyrA PE=3 SV=1
-------HDTLLCFSSRGKVYWKKVYELPQGSRVARGKPFVNLLP-ERINTVLSIRKDKYIFMVTASGVVKKTSLADFSRPRS--SGI---IALDLREGD
QLVGADLT---DGVQEIMLFSSGGKVIRFSERDVRPVRARGVKGMELPSHR-VIALIIAA-SGTILTATELGYGKRTAIAEYRLQGRGGRGIISIRTTNG
E-VVGAVQVEKEDEVVLISDGGTLIRTPVDNISLMGRNTQGVKLINLQ-EG-ERLVGIERIV--------------------------------------
------------
>tr|K0C2K2|K0C2K2_CYCSP DNA gyrase subunit A OS=Cycloclasticus sp. (strain P1) GN=gyrA PE=3 SV=1
-------HDTVLCFSSKGKVYWLRVFNLPVASRVARGKPIVNLLP-ERINAILPIREDEYIFMATESGTVKKTHIKEFEKPRA--NGK---IAIDLRDDD
TLVGVAVT---DGEKDVMLFASSGKVASFKEADVRVMRASGVRGMRLKDEH-IISLIISE-PGTVLTLTQNGYGKRTKIEEYPIHKRGGQGVIAMQTSNG
A-LVGAVLVDESDELMLITDGGTLVRTRTSEISILGRNTQGVRVIRPA-KN-EKVIGLDRIA--------------------------------------
------------
>tr|A0A0A0BC32|A0A0A0BC32_9GAMM DNA gyrase subunit A OS=Methylophaga thiooxydans GN=gyrA PE=3 SV=1
-------HDTLLCFSSAGKVYWKKVYELPQGGRTARGKPIVNLLP-ERINAVLSIRADKFIFMATASGTVKKTPLVDYSRPRA--NGI---IAVDLKDDD
QLVDVAVT---DGMSDIMLFSSTGKVIRFPEADVRSMRSRGVRGMRIADEK-IISLIIAQ-EGAILTATEFGYGKRTNLAEYRVQGRGGQGIISIQTSNG
S-VVGAVQVCDEDQIMLITNGGTLVRTPVKDVSLVGRNTQGVRLINLS-KN-EKLVGVERVL--------------------------------------
------------
>tr|U1MR33|U1MR33_9EURY DNA gyrase subunit A OS=Haloquadratum walsbyi J07HQW1 GN=gyrA PE=3 SV=1
-------HDYLLYFTNHGQVYQLKTYQIPEMSRTARGKSAVNLLDDEQITAVVNTADERYLTMVTQSGYIKRTSVTSFQNIRS--TGI---IAINLGADD
TLIDVEVT---DGNRDIILGTRKGMAIRFDE--VRSMRARGVHGIKLE---TVAALAAVHDDDWVLTVTEHGYGKRTDIDQYRQQSRNGKGLIDI--NNG
C-VCEVETVKGDDELFIMSRNGQILRTPVNDISTVGRNTMGVIVMDLED-D-DTVTSVDIHP--------------------------------------
------------
>tr|U1PMA5|U1PMA5_9EURY DNA gyrase subunit A OS=Haloquadratum walsbyi J07HQW2 GN=gyrA PE=3 SV=1
-------HDYLLYFTSHGQVYQLKTYQIPEMSRTARGKSAVNLLEDEEITAVVNTANERYFTMVTQSGYIKRTSVNSFQNIRA--TGI---IAIDLDADD
ELIDVEVT---DGSQDIILGTRKGMAIRFDE--VRSMRARGVHGIKLE---AVAALAAIDEDEWVLTVTEHGYGKRTNIDRYRQQSRNGKGLIDI--NNG
R-VCEVETVGADSELFIMSRNGQILRTPVSDISTVGRNTSGVIVMDLDT-N-DTVASVDIHP--------------------------------------
------------
>tr|G0LLH1|G0LLH1_HALWC DNA gyrase subunit A OS=Haloquadratum walsbyi (strain DSM 16854 / JCM 12705 / C23) GN=gyrA PE=3 SV=1
-------HDYLLYFTSHGQVYQLKTYQIPEMSRTARGKSAVNLLEDEQITAVVNTAEERYFTMVTQSGYIKRTSVNSFQNIRS--TGI---IAISLGADD
KLIDVEVT---DGNQDIILGTRKGMAIRFNE--VRSVRARGVHGIKLE---AVAALAAVDDDDWVLTVTEHGYGKRTDIDRYRQQSRNGKGLIDI--NNG
H-ICEVETVGISDELFMMSRKGQILRTPVDDISTVGRNTMGVIVMDLED-T-DTVASVDTHP--------------------------------------
------------
>tr|Q82FD2|Q82FD2_STRAW DNA gyrase subunit A OS=Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 81
-------HHWLLFFTNKGRVYRAKAYELPDAGRDARGQHVANLLAPEAIAEILAIRVP-YLVLATKGGLVKKTPLKDYDS-RS--GGV---IAINLREDD
ELIGAE-----SAEDDLLLISKKAQSIRFTE--LRPMRTSGVKGMSFR-G-DLLSMNVVRPGTFVFTATDGGYAKRTAVDEYRVQGRGGLGIKAAKIVRG
S-LVGALVVET-DEILAITLSGGVIRTRVNEVRE-GRDTMGVQLINLGK-R-DAVVGIARNA--------------------------------------
------------
>tr|D0L0F0|D0L0F0_HALNC DNA gyrase subunit A OS=Halothiobacillus neapolitanus (strain ATCC 23641 / c2) GN=gyrA PE=3 SV=1
-------HAWALMFTNLGRVYWRKVYQLPQGARGARGRPVVNILP-ERVNALLPVRDDHYIFFATATGQVKKTPLVDFSRPRQ--AGI---IAIDLRDDD
RLVGARLT---DGSRELMLFSNAGKSIRFAEADVRSMRAGGVRGIRMDE--QVVSLLV-VGEGQVLTATEHGYGKRTPIDDFPLQGRGGQGVIAIQTSNG
A-LVGAALVQDEDEVILISDAGTLVRTEISQISSVSRNTQGVILIRLS-DD-EKLVQLAAVS--------------------------------------
------------
>tr|F9ZN26|F9ZN26_ACICS DNA gyrase subunit A OS=Acidithiobacillus caldus (strain SM-1) GN=gyrA PE=3 SV=1
-------HATVLFFSNLGKVFWQKVYQLPQSGRSARGKPIVNLLS-EGITTVLPVREGQYVCMVTAHGVVKKTPLMEYSRPRS--QGI---NAINLDPGD
RLVAVCLS---DGQREFMLFTRKGMAVRFPEDKVRPMRARGVRGISLDA--DVISAQIVDPDQVILTATAKGYGKLTNVEEYRRTNRGGKGVIAIQTNNG
Q-VVGALAVKESDELMLVSNGGTLIRIAVQGIRRTGRNAQGVRLIQLA-PD-EQLAGLALIA--------------------------------------
------------
>tr|A0A0R1RY98|A0A0R1RY98_9LACO DNA gyrase, A subunit OS=Lactobacillus fuchuensis DSM 14340 = JCM 11249 GN=FC69_GL001159 PE=4 SV=1
-------HEVLLFFTNTGKVYRAKGYEIPEYGRTAKGIPIINLLGNERVQTVVNLGDEQALFFITRLGTVKRTSVSEFAN-RS--NGL---KALTLKEDD
ELINVL-T---DG-QNIFIGTHNGYAVSFSE--VRSMRAAGVRGIRLR---GVVGSDLLIPGQEILVISEKGYGKRTTVSDYPIKGRGGKGIKTANITNG
P-LAGITAVTE-EDILLITDTGVLIRFQVANVSQTGRATLGVRLIRVDDQ--AKVATMAKVE--------------------------------------
------------
>tr|A0A0R2AW55|A0A0R2AW55_9LACO DNA gyrase subunit alpha OS=Lactobacillus brantae DSM 23927 GN=FC34_GL001335 PE=4 SV=1
-------HDMLLFFTNTGKVYRNKGYEIPEYGRTAKGIPIINLLGDEKVQTVINVDSERFLFFVTRNGVVKRTPVSDFAN-RS--NGL---IALNLKDDD
ELSNVI-T---DG-DTIFIGTHRGYSVTFKE--VRSMRATGVRGIRLR---EVVGSDVLAPDSEVFVISENGYGKRTSASEYPTKGRGGKGIKTANITNG
P-LAGVTTVND-EDILVMTDAGVMIRFSVASVSQTGRSTLGVRLIRVDDD--AKVATMAKVE--------------------------------------
------------
>tr|A0A0P8BWU5|A0A0P8BWU5_9CYAN DNA gyrase, A subunit OS=Phormidium sp. OSCR GN=gyrA PE=4 SV=1
-------HDQILFFSDRGVVYSVKAYQIPTGSRTSRGIPIVQLLPREKITSVVPVSDDNYLIMLTRGGNIKKTALSAFANIRA--NGL---IAISLSDGD
ELRWVRLA---RAEDSIIIGSRLGMAIHFKA--LRPLRTRGVKSMNLR---DLISMDVLPSGPWVLIVTTGGYGKRVPVSQFRLQRRAGKGTISTKFHDD
S-VVGLIVVN-DDELMMVTMRGIIIRQAASAITPQSRSATGIRVQRLDK-D-DAIAAVAIVP--------------------------------------
------------
>tr|A0A061LUJ5|A0A061LUJ5_9MICO DNA gyrase subunit A OS=Leucobacter sp. UCD-THU GN=gyrA PE=3 SV=1
-------HHWLLFFTNTGRVYRAKTYEVPEGGRDSKGQHLANLLAPETVTQILDVRAG-YLVLATRDGLVKKTALPEYDT-RT--GGI---IAIKLREGD
ELVSAL-----ESSDDVLLVSKHGMSVRFTQ--LRPMRTSGVRGMNFR-G-DLLSASRINGEGYVFVVTEGGYAKRTAVDEYRVQNRGGYGIKVAKLDRG
D-LVGALIVET-DEVLAVLASGKVVRSAVAEVPA-GRNTMGVVFARFPE-R-DRIIGIARNT--------------------------------------
------------
>tr|A0A075U492|A0A075U492_9LACT DNA gyrase subunit A OS=Weissella ceti GN=gyrA PE=3 SV=1
-------HDTLLFFTNAGKVYKLKGYEIPEYGRTAKGIPVINLLGEETIQTMISVNSDDYLFFTTRDGVVKRTAISEFGN-RA--HGL---RAINLREND
ELIKVM-T---VD-DNILIATQGGYAVSFKM--IRAMRAAGVRGINLR---NVIGAEVLVDDAHVLVITQNGYGKKTAVSEYPIKGRGGKGIKTAQITNG
P-LAGVAVVQG-EDVVLTTNMGVMIRFNVATVSETGRATQGVRLIRLDEE--ATVATFTTVE--------------------------------------
------------
>tr|A0A0R2FVZ8|A0A0R2FVZ8_9LACT DNA gyrase subunit A OS=Weissella halotolerans DSM 20190 GN=IV68_GL000506 PE=4 SV=1
-------HDTLLFFTNSGKVYRLKGYEIPEYGRSAKGIPVINLLGSEAIQTVINIHSEDDLFFTTRDGVVKRTPISEFSN-RN--NGL---RAINLHEDD
ELINVM-T---DG-HNVLLGTHGGYAVSFNV--VRSMRAAGVRGIRLR---DVVGAQVLEPEDDVLVITENGYGKMTPASEYPIKGRGGKGIKTAQVTNG
P-LVGVSVVKH-EDVILTTNLGVMIRFNVDNVSLTGRATQGVRLIRLDDD--SKVATFTTVA--------------------------------------
------------
>tr|A0A069CYN9|A0A069CYN9_9LACT DNA gyrase subunit A OS=Weissella oryzae SG25 GN=gyrA PE=3 SV=1
-------HDTLLFFTNMGKVYKMKGYEVPEYGRTAKGIPVVNLLGEEKVQAVLNVRSKDYIFFTTREGVVKRTPVTEFSN-RT--HGL---RAINLHDSD
ELISAQ-T---DG-QKILIGTHGGYAVSFQE--VRSMRAAGVRGINLR---DVIGAEVLPADSKVLVITENGYGKQTASDEYPTKGRGGKGIKTAQITNG
P-LAGITVVNN-EDIMLTTNKGVMIRFTADSVSETGRATQGVRLIRLDED--AKVATLAKVE--------------------------------------
------------
>tr|F8I199|F8I199_WEIKK DNA gyrase subunit A OS=Weissella koreensis (strain KACC 15510) GN=gyrA PE=3 SV=1
-------HDTLLFFTSLGKVYRMKGYEIPEYGRTAKGIPVINLLGDEQVTKIINVRSNDYLFFVTQQGVVKRTSVSEFGN-RT--NGL---KALTLHDED
ELIAVL-S---DG-QEIFIGTHDGYSVSFSE--VRSMRAAGVRGIRLR---GVVGADVRHDGDEVLVITENGYGKRTSVSEYPVKGRGGKGIKTANITNG
S-LVGISIVSD-EDVMLTTDQGVMIRFTVDSVSQTGRATQGVRLMRLGSE--TKVATFTKMD--------------------------------------
------------
>tr|A0A0R2H9I9|A0A0R2H9I9_WEIVI DNA gyrase subunit A OS=Weissella viridescens GN=IV50_GL000528 PE=4 SV=1
-------HDTLLFFTNTGRVYRLKGYEVPEYSRTAKGIPVVNLLGDESIQTVISVQSEDYLFFTTRQGVVKRTPVSDFGN-RT--SGL---RAINLRDED
ELINVL-A---NG-SNILIGTHNGYAVSFNS--VRSMRAAGVRGINLR---DVIGAQALEDDKYVLVITENGYGKKTPVSEYPIKGRGGKGIKTAQITNG
P-VAGIAVVDD-EDIMLTTNMGVMIRFSVDAVSETGRATQGVRLIRLDGD--SKVATFTTVD--------------------------------------
------------
>tr|A0A0R2JJC4|A0A0R2JJC4_9LACT Uncharacterized protein OS=Weissella kandleri GN=IV73_GL000350 PE=4 SV=1
-------HDTLLFFTSLGKVYRMKGYEIPEYGRTAKGIPVINLLGDEQVTKVINVRSKDYLFFVTRQGVVKRTPIADFSN-RT--NGL---KALTLHDDD
ELIAVL-S---DG-QEIFIGTHNGYSVSFNE--VRSMRAAGVRGIRLR---GVVGADVRHADEEVLVITENGYGKRTAIGEYPIKGRGGKGIKTANITNG
P-LVGVVVVKS-EDIMLTTDQGVMIRFTVDTVSQTGRSAQGVRLMRLGDE--AKVATFTKIE--------------------------------------
------------
>tr|G0UEL9|G0UEL9_9LACT DNA gyrase subunit A OS=Weissella thailandensis fsh4-2 GN=gyrA PE=3 SV=1
-------HDTLLFFTNSGKVYKMKGYEIPEYGRTAKGIPVVNLLGEESIQAVINVRSEDYLFFTTRQGVVKRTPVNEFGN-RT--HGL---KAINLHDGD
ELINVL-T---DG-QNIIIGTHGGYAVSFNS--VRSMRAAGVRGITLR---DVVGAQVLIENGHVLIITENGYGKQTAVDQYPIKGRGGKGIKTAQVTNG
P-LAGLKVVDS-EDIMLTTNKGVMIRFTVDSISETGRATQGVRVIRLDDG--SAVATFAKVE--------------------------------------
------------
>tr|A0A0N7HAG7|A0A0N7HAG7_9LACT DNA gyrase subunit A OS=Weissella cibaria GN=AO080_01925 PE=4 SV=1
-------HDTLLFFTNAGKVYKMKGYEIPEYGRSAKGIPVVNLLGEESVQTVINVRSEDFLFFTTRYGKVKKTPVSDFSN-RT--HGL---KAITLNDDD
ELINVM-T---DG-ENLLIGTHGGYAVSFNA--VRSMRAAGVRGITLR---DVIGAEILKDDASVLVITEKGYGKQTPVDQYPIKGRGGKGIKTAQITNG
P-LAGLAVVDS-EDIMLTTNKGVMIRFTVDSVSETGRATQGVRVIRLDDD--AIVATFAKVE--------------------------------------
------------
>tr|R9JKQ8|R9JKQ8_9FIRM DNA gyrase subunit A OS=Lachnospiraceae bacterium A4 GN=gyrA PE=3 SV=1
-------HHYLMFFTNFGRVYRLKTYEIPEAGRTARGTAIVNLLQPEKISAMIPIREGKHLFMVTKRGITKKTPIMEFSN-RK--NGL---AAISLRDDD
ELIEVK-T---DE-SEIFLITKYGMCIRFKE--VRAMRAMGVIGMNLD---GIIGMQLNTQGDALLIVSEMGMGKRTLLDEFTVQKRGGKGVRCYRITTG
N-VVGIKGVND-HEVMMITTEGVIIQIPVGDISIYGRNTSGVKLINLDDEN-VKVAKIAKVR--------------------------------------
------------
>tr|R9MN66|R9MN66_9FIRM DNA gyrase subunit A OS=Lachnospiraceae bacterium 10-1 GN=gyrA PE=3 SV=1
-------HHYIMFFTNYGRVYRLKTYEIPEASRTSRGIAIVNILQPEKISAIIPVKKNKNLFMVTKNGIVKKTSIIEYSN-RK--NGL---AAINLRDDD
ELIEVK-T---DK-TEIFLVTKYGMCIRFRE--VRATRSMGVIGMNLG---GIVGMQLDHQGDSLLIVSENGMGKRTYLDEFTVQKRGGKGIKCYKITTG
D-VIGVKAVND-HEIMMITTGGIIIQIRMEDISKLGRITSGVKLINLDQ-G-VTVAQIAKVR--------------------------------------
------------
>tr|R9KRX1|R9KRX1_9FIRM DNA gyrase subunit A OS=Lachnospiraceae bacterium COE1 GN=gyrA PE=3 SV=1
-------HHYLMFFTNFGRVYRIKAYEIPEAGRTARGTAIVNILQPEKITAMIPISDGKHLFMITKKGIAKKTPIMEFSN-RK--SGL---AAISLRDDD
ELIEVK-T---DE-SEIFLVTKYGMCIRFKE--VRSMRAMGVIGMNLD---GIVGMQLNTQGERLLIVSEMGMGKRTNIDEFTVQKRGGKGIKCYRIATG
N-VVGVKAVKD-SEVMMITTEGVIIQISVEDISIYKRNTSGVKMINLDE-G-VTVAKVAKVK--------------------------------------
------------
>tr|R7R767|R7R767_9FIRM DNA gyrase subunit A OS=Roseburia sp. CAG:100 GN=gyrA PE=3 SV=1
-------HHYLMFFTNYGRVYRLKAYEIPEAGRTARGTAIINLLQPEKISAMIPISEGKNLFMITKNGIAKKTPVIEFSN-RK--TGL---AAINLREDD
ELIEVK-T---DA-SEIFLVTKYGMCIRFKE--VRAMRAMGVIGMNLE---GIVGMQLNTQGDSLLIVSEKGMGKRTRMDEFSVQKRGGKGVKCYKIATG
N-VIGVKAVNS-HEIMMITTEGIIIQLRMEDISMIGRNTSGVKMINLDE-G-VTVARIAKVR--------------------------------------
------------
>tr|R7N2R5|R7N2R5_9FIRM DNA gyrase subunit A OS=Firmicutes bacterium CAG:95 GN=gyrA PE=3 SV=1
-------HHYIMFFTNFGRVYRLKTYEIPESGRTSRGVAIVNLLQPEKVSAIIPIKENKNLFMVTRKGIVKKTSVVEYSN-RK--NGL---TAINLREDD
ELIEVK-T---DK-TEIILVTRFGMCIRFKE--VRSTRSMGVIGMSLN---QIVGMQLDHQGDSLLIVSEKGMGKRTFLEEFTVQKRGGKGVKCYKITTG
Y-VVGVKAVNE-NEIMLITTGGIIIQIPMSDVSILGRITSGVKLINLDNG--VTVAQIAKVR--------------------------------------
------------
>tr|Q11UG4|Q11UG4_CYTH3 DNA gyrase subunit A OS=Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469) GN=gyrA PE=3 SV=1
-------HNYLLFFTEYGKVFWLKVYEIPEGGKTTKGRAIQNVIQPDKVRTVINVKNNNYLVMCTEQGVIKKTTLEAYSR-RS--GGI---NAITIHEGD
RLLDVKMT---SGSDELVIALRSGRAIRFN---VRPMRAAGVKGVTLAD--DVVGLVAVSSDTTLLVVSEKGYGKRSDIEDYRVTNRGGKGVKTLNISTG
D-LVSILGVN-QYQIMIINKSGITIRMAVSDLRVMGRATQGVRLIKIQD-G-DSIASVAKFE--------------------------------------
------------
>tr|A0A0Q4B9F6|A0A0Q4B9F6_9BACE DNA gyrase subunit A OS=Candidatus Bacteroides periocalifornicus GN=AL399_00775 PE=4 SV=1
-------HHTLLFFTESGRCYWLKGYEVPEGARDSKGRTLQNLISPDKVRAIINVRSSHYVVMCTRCGVVKKTLLSEYSR-RS--TGI---IAVNIREQD
QLLEAVLT---DGQGELMLASRHGQAVRFN---LRALRSTGVIGMRLE---DVVGMVAVQPERTLLVVSDSGFCKRSPID-YRKTNRGSKGVKTLNVAAG
E-VVGISLVS-DEDLMIISRNGVIIRFPVAQTHVASRNTKGVHCIALGK-G-DTIASISPVA--------------------------------------
------------
>tr|A0A0E3V742|A0A0E3V742_9BACT DNA gyrase subunit A OS=Spirosoma radiotolerans GN=gyrA PE=3 SV=1
-------HNTLLAFTQKGRLYWLPVYELPEGSRLSKGRPLANFINSDKVRAVINVTNNNYIVMCTRNGTIKKTMLEAYSR-RQ--NGI---IAITIDEDD
QLLGVCMT---NGDNDIVIASSAGKAVRFH---VRPMRAAGVRGISLDEA-DVVGMVCISSDAQLLVVSQNGYGKRSDIEEYRITNRGAKGVGTLKVTVG
R-LVAVLDVA-TDDLMIINKSGIAIRTPVEAISVIGRNTQGVRLIKLNE-G-DEISSVTKIK--------------------------------------
------------
>tr|A0A0N0CZ00|A0A0N0CZ00_9BACT DNA gyrase subunit A OS=bacterium 336/3 GN=gyrA PE=3 SV=1
-------HNYLLIFTESGKVFWKKVYEIPEGSKTAQGRAIQNLIQQDKVRAVINVENNHFLIMCTEKGTIKKTTLEAYSR-RA--NGI---NAININEGD
KLIEVRMT---TGSDHIILATKSGRAIHFH---VRPMRATGVRGIWLDQP-DVIGMVCVGSDTNLLVVSERGYGKRSDTTEYRITSRGGKGVKAMSVTTG
K-LVAIKDVS-TDDLMIINKSGITIRMKVETLRVQGRATQGVRLITLNK-E-DEISSIAKIE--------------------------------------
------------
>tr|I2GHM1|I2GHM1_9BACT DNA gyrase subunit A OS=Fibrisoma limi BUZ 3 GN=gyrA PE=3 SV=1
-------HNTLLIFTQKGRLYWLPVYKLPEGTRTAKGRPLANFINSDKVRAVINVKNNNYVVMCTRQGTIKKTLLEAYSR-RQ--NGI---IAITIDEDD
QLLGVCLT---NGDNEIVIASSAGKAVRFH---VRPMRAAGVRAITLDES-DVVGMVCIDSDAQLLVVSEKGYGKRSEIDEYRVTNRGAKGVGTLKVTVG
K-LVAVLDVT-NDDLMIINRSGIAIRMAVSDVSVIGRNTQGVRLIRLNE-G-DEISSVTKIE--------------------------------------
------------
>tr|A0A0L8ANA8|A0A0L8ANA8_9BACT DNA gyrase subunit A OS=Roseivirga sp. D-25 GN=gyrA PE=3 SV=1
-------HDYLLIFTEFGKVFWKKVWELPEGNKTAKGRPVQNLINPDRIRAVINVQNNNYVVMCTELGTIKKTSLEAYSR-RT--NGI---NAITINEGD
RLLEVKFT---NGDNHIIIGARSGRAIHFH---VRPMRAAGVRAFRLAD--DVIGMVCVNREANLLVVSENGYGKRSPIDDYRITKRGGKGVKTINVTTG
N-LVAIKEVV-SDDLMIINKSGITIRISVESLRVMGRATQGVKLIRLNE-G-DAISSVEKIQ--------------------------------------
------------
>tr|A0A0D3LAX6|A0A0D3LAX6_9BACT DNA gyrase subunit A OS=Flammeovirgaceae bacterium 311 GN=gyrA PE=3 SV=1
-------HNYLLIFTENGKVYWIKVYEIPEGSKVSKGRAVQNIINPDRVRAVLNVENNNFIMMCTVQGTIKKTTLEAYSR-RQ--NGV---NAITINPGD
RLLDVKMT---NGDNHIVLGLESGRAIHFH---VRPMRAAGVRGIAVGE--DVIGMVCVARDASLLVVTEHGYGKRSVVEEYRITRRGGKGVKALKISTG
K-LVAIKEVI-TDELMIINRSGITIRMKVDDLRIMGRATQGVRLIRLNE-N-DSISSVEKIE--------------------------------------
------------
>tr|A0A0E3ZH86|A0A0E3ZH86_9BACT DNA gyrase subunit A OS=Pontibacter korlensis GN=gyrA PE=3 SV=1
-------HHHMLFFTEFGRVFWLKVYEIPEGGKTTKGRAIQNLIQRDKVRAVLNVHLNHNLVFITEQGTIKKTVLEAYSR-RT--NGI---NAISINDGD
RLLDVQLT---NTSSEIVIALESGRAIRFN---VRPMRAAGVRAVTLA-P-DVVGMVCVENNTDLLVVSEKGFGKRSPLEEYRITNRGGKGVKTMNITTG
K-LVAIKGVT-TDDLMIINRSGITIRLRVSDLRVIGRATQGVRLIKLNE-G-DQISSVAKVE--------------------------------------
------------
>tr|J0V6V8|J0V6V8_9BACT DNA gyrase subunit A OS=Pontibacter sp. BAB1700 GN=gyrA PE=3 SV=1
-------HHHMLFFTEFGRVFWMKVYEIPEGGKTTKGRAIQNLINKDKIRAVINVRLNHNLVFCTEQGTIKKTVLEAYSR-RT--NGI---NAITINEGD
RLLDVQLT---TGNSEIIIALGSGRAIRFN---VRPMRAAGVRGVTLA-P-DVVGMVCVENNTELLVVSENGFGKRSLLEEYRITNRGGKGVKTLNVTTG
N-LVAIKGVV-TDDLMIINRSGITIRLRVADIRVIGRATQGVRLIKLTE-G-DQISSVAKVE--------------------------------------
------------
>tr|A0A0M4HPY0|A0A0M4HPY0_9BACT DNA gyrase subunit A OS=Hymenobacter sp. DG25A GN=gyrA PE=3 SV=1
-------HEYLLFFTELGRVFWLKVYEVPEGGKNTKGRPIQNLIERDSVRSVLNVRENTFLMFCTEQGTVKKTPLEAYSR-RT--AGI---NAISINEGD
RLLDVQLT---TGNSEVIVALNTGRAVRFH---VRSMRAAGVRGITLV-A-DVVGMVCVSDTQELLVVSEKGYGKRSELEEYRITNRGGKGVRAMKITTG
A-LVAIKAVN-SDDLMIINRSGITIRLRVADLRTIGRATQGVRLLKISE-G-DAISSVAKVE--------------------------------------
------------
>tr|I0KAM7|I0KAM7_9BACT DNA gyrase subunit A OS=Fibrella aestuarina BUZ 2 GN=gyrA PE=3 SV=1
-------HNTLLIFTQKGRLYWLPVYKLQEGSRDAKGKPLPNYIQSDKVRAVINVKKNNFIVMCTEQGTIKKTLLEAFSN-RR--TGI---IAITIEEGD
RLLDVVMT---NGDNDLVIASRAGKAVRFH---VRPMRAAGVKGITLDEA-DAVGMVCIGR---LLVLSENGYGKRSPID-YRVTNRGAKGVGTLKVTVG
A-LVGILEAS-SDDLIVINRSGVLLRTPVRNISVIGRNTQGVRVISIRD-G-DAISSVTTVT--------------------------------------
------------
>tr|A0A098LJK1|A0A098LJK1_9BACT DNA gyrase subunit A OS=Sporocytophaga myxococcoides GN=gyrA PE=3 SV=1
-------HNYLLIFTDSGKVFWQKVYGIPEGSKTSKGRPIQNLINKDKVRAIINVKNNNFIIMVTENGTIKKTSLEAFSR-RS--NGI---QAITINEGD
KLLNVRLT---NGSNEIVIALKSGRAIRFN---VRPMRAAGVRGVTLAD--DVIGMVCLSCDNNLLVVSEKGYGKRSDIDDYRVTNRGGKGVKTLNITTG
K-LVAIMDVS-KDELMIINKSGITIRMPVSDLRVVGRATQGVRLIKLSE-T-DEIASIAKIE--------------------------------------
------------
>tr|A0A0H4W559|A0A0H4W559_9BACT DNA gyrase subunit A OS=Rufibacter sp. DG31D GN=gyrA PE=3 SV=1
-------HNYLLIFTESGRVFWLKVYEVPEGGKTTKGRAIQNLINKDKVRAVINVHINNYLVFCTEQGTIKKTPLEAYSR-RA--TGI---QAITINEGD
RLLDVQLT---NGANDIIIALKSGRAVRFP---VRTMRAAGVRGITLA-P-DVVGMVCVHNDTNLLVVSEKGFGKRSLLEEYRITNRGGKGVKTLNVTTG
H-LVAIMGVI-TDDLMIINKSGISIRLRVADLRVIGRVSQGVRLLRLNE-G-DEISSVAKIE--------------------------------------
------------
>tr|W8F193|W8F193_9BACT DNA gyrase subunit A OS=Hymenobacter swuensis DY53 GN=gyrA PE=3 SV=1
-------HEYLLFFTEAGRVFWLKVYEVPEGGKNTKGRPIQNLIERDSVRSVLNVRDNTFLMFCTEQGTVKKTPLEAYSR-RT--AGI---NAITINEGD
RLLDVQLL---NGNSEVVLALRSGRAVRFP---VRSMRAAGVRGITLSEA-DVVGMVCLDKQDELLVVSENGYGKRSPLEEYRITNRGGKGVRAMKLTTG
Q-LVTIKTVN-TDDLMIINKSGITIRLRMSELRSIGRATQGVRLLKISS-G-DEISSVAKVA--------------------------------------
------------
>tr|A1ZUE0|A1ZUE0_9BACT DNA gyrase subunit A OS=Microscilla marina ATCC 23134 GN=gyrA PE=3 SV=1
-------HDYLLIFTNSGKVFWIKGYNIPEVAKTAKGRAIQNLLQKDSIRAVINVKQNHYLVMCTEKGIIKKTRLEAFSR-RQ--NGI---HAITINEDD
QLLDVKLT---NGENNIILAIRSGRAIHFH---VRSMRAAGVRGITLDD--NVVGMVCVARDASLLVVSETGYGKRSSIEDYRITNRGGKGVITMQITTG
R-LVAIKEAV-TDDLILITKTGLAIRMSMSDMRVMGRATQGVRLIKLHE-D-DSIASVAKVD--------------------------------------
------------
>tr|R6KY85|R6KY85_9FIRM DNA gyrase subunit A OS=Coprococcus sp. CAG:131 GN=gyrA PE=3 SV=1
-------HNFIMFFTNMGRVYRMKGYEIPESGRNARGVAIVNLLQPEKVTAIIPIA-KKYLMMATKNGIVKKTKIEAFEN-RK--TGL---AAITLNEGD
ELIEVK-T---SG-NDVFLVTAKGMCIRFNE--VRDTRSMGVRGIRCD---GVIAMQLDVQGDEMLFVTTKGMGKRTELSEFAPQMRGGKGVKCYRITTG
D-IVSAKAVTD-HDIMMMTNEGIMIRMHCSDITVIGRITSGVKLMNIGKDN-TFVASVAKLA--------------------------------------
------------
>tr|R5JY71|R5JY71_9FIRM DNA gyrase subunit A OS=Coprococcus sp. CAG:782 GN=gyrA PE=3 SV=1
-------HHYIMFFTNKGRVYRLKGYDIPESSRTARGVAIVNLLEPEKVTAIIPFKENKYLFMATKNGMIKKTPLIDYVN-KK--SGL---IAIDLKDDD
DLIEVK-T---DG-DDMFLITEGGMCIRFNE--VRSTRTMGVKGISLS---DVISLIMGSHGNHILFVTKNGMGKKTDINEFSSQNRGGKGLKCYKITTG
N-LVGAKIVNE-NEMMLITNEGIIIRFDSSDVSALGRVTSGVKLMNIDYEG-VFVAAITKVR--------------------------------------
------------
>tr|M1LMM8|M1LMM8_9PROT DNA gyrase subunit A OS=Candidatus Kinetoplastibacterium desouzaii TCC079E GN=gyrA PE=3 SV=1
-------HDFLLFFSDLGRVYWLKVWEVPQGTRGSKGKPIVNMFP-EKITVVLPVK-NLYVFMATANGVVKKTSLSDFSNPRK--NGI---IAVGLDDGD
YLIGAELT---NGDYDIMLFSDSGKAVRFSEKDVRSVRARGVRGMVLG--KNVVSLLVSNS-KSVLIATENGFGKRTSIKHYTVHNRSTKGMIAIQNSNG
K-VVGAVLVDLSDEIMLITTSGVLVRTRVSEIRKMGRVTQGVTLININ-SG-SYLSKIRKVI--------------------------------------
------------
>tr|M1M1J2|M1M1J2_9PROT DNA gyrase subunit A OS=Candidatus Kinetoplastibacterium galatii TCC219 GN=gyrA PE=3 SV=1
-------HDYLLFFSDLGRVYWMKVWETPQGTRGSRGKPVVNMFP-EKITVVLPVK-DLYIFMATARGIVKKTPLSDFSNPRR--SGI---IAVVLGEGD
YLIGAELT---DGKHDVMLFSDSGKAVRFYENDVRSMRSRGVRGMSMD--SKVISLLVAND-KSVLVATENGFGKRTSIKEYTRHNRGTKGMISIQTSNG
R-VVGAVLVKPDDEIMLITNGGVLVRTRVSEIRQMGRVTQGVKLMNVD--G-SLLSGVRRVV--------------------------------------
------------
>tr|A0A0R1W7R8|A0A0R1W7R8_9LACO DNA gyrase, A subunit OS=Lactobacillus concavus DSM 17758 GN=FC15_GL000510 PE=4 SV=1
-------HDTLLFFTNTGKVYRAKGYEIPEYGRTAKGLPIINLLGDENVETVINVHDEDSLFFITRLGTVKRTTVGEFSN-RA--NGL---RALTLRDGD
ELSNVL-T---DG-QNILIGTHLGYAVSFNE--VRSMRAAGVRGIRLR---QVIGSAVLTPDQEILTISENGYGKRTAVSEYPIKGRGGKGIKTANITNG
P-LAGLTVVNS-EDLMLITTEGVLIRFPVANVSQTGRATLGVRLIKVDNG--TKVATLAKVD--------------------------------------
------------
>tr|A0A0R2DSS2|A0A0R2DSS2_9LACO DNA gyrase, A subunit OS=Lactobacillus floricola DSM 23037 = JCM 16512 GN=FC86_GL001228 PE=4 SV=1
-------HDVVLFFTNTGKVYRAKGYEIPEFGRAAKGIPIINLLGDEKVQTVISVEVDQFLFFITKNGTVKRTPISDFKN-RS--KGI---RSITLKEDD
ELNNVL-T---DG-QTIFIGTHKGYAVTFSE--IRSMRAAGVRGIRLR---GVIGSDIITPDSNVLVISEKGYGKQTKATHYPIKGRGGKGIKTVNVTNG
P-LAGIRVVNH-EDIMLITDEGVLIRFKVANVSETGRAALGVRLIKVSEN--SKVATLTTVP--------------------------------------
------------
>tr|A0A0F4KZW4|A0A0F4KZW4_9LACO DNA gyrase subunit A OS=Lactobacillus mellis GN=gyrA PE=3 SV=1
-------HDDLLFFTNSGKIYHSKGYEIPEYGRSAKGIPIINLLGDERVQAVVHIKLAKYLFFVTRLGTVKRTKLEEFQN-RK--NGL---RAITLKADD
SLDNVL-T---DG-QNILIGTHLGYAVTFKE--VRVMRAAGVRGIRLR---QVVGSDILAAQSEVLVISEQGYGKRTAASEYPIKGRGGKGIKTANITNG
P-LAGITTVKD-EDIMVITSNGVMIRFEVANVSQTKRATMGVRLIKINDA--EQVSTMAKVD--------------------------------------
------------
>tr|A0A0R1GGU8|A0A0R1GGU8_9LACO DNA gyrase, A subunit OS=Lactobacillus bifermentans DSM 20003 GN=FC07_GL001269 PE=4 SV=1
-------HDMLLFFTNTGKVYRAKGYEIPEYGRTAKGIPVINLLQDETIQTVINVS-DQYLFFTTRLGVVKRTPVSEFHN-RS--NGL---KAITLKEND
QLIQVS-T---DG-QNLIIGTHLGYAVSFAE--VRSMRASGVRGIRLR---DVVGADLLTADNKVLVISEKGYGKQTPSDQYPIKGRGGKGVKTSNVTNG
P-LTGLVTVND-EDVMLMTDTGVAIRFHVKDVSETSRATLGVRLIRVDDN--AKVATIAKVQ--------------------------------------
------------
>tr|A0A0F4LX28|A0A0F4LX28_9LACO DNA gyrase subunit A OS=Lactobacillus mellifer GN=gyrA PE=3 SV=1
-------HDTLLFFTNTGKIYRSKGYEIPEYSRNAKGIPIINLLGDERVQAVVHLPEQQFLFFVTKQGTVKRTAISEFQN-RK--NGL---RAITLKDQD
SLDNVM-T---NG-QNILIGTHLGYAVTFAE--VRQMRAAGVRGIRLR---QVVGSAILKPNSEVLVISEKGYGKRTPAAEYPIKGRGGKGIKTSNITNG
P-LAGITTVEQ-EDIMIITDKGVLIRFAVSDVSQTGRSTLGVRLMKTNDD--AIVSTMAKVE--------------------------------------
------------
>tr|J3ERZ9|J3ERZ9_9LACO DNA gyrase subunit A OS=Lactobacillus coryniformis subsp. coryniformis CECT 5711 GN=gyrA PE=3 SV=1
-------HDMLLFFTNTGKVYQAKGYEIPEYGRTAKGIPVINLLEDERIQTVVNVASDNYLMFTTREGVTKRTAVSEFHN-RS--NGL---KAITLKESD
ELINVC-T---DG-QNIIIGTHLGYAVSFAE--VRSMRATGVRGIRLR---GVVGSDILSPDSEVLIISEKGYGKRTPAAQYPIKGRGGKGIKTVNVSNG
P-LAGLATVKD-EDIMLITNTGVVIRFHVRDVSQTGRATLGVRLIRVDDE--AKVATMAKVA--------------------------------------
------------
>tr|A0A0K2JDM5|A0A0K2JDM5_9FUSO DNA gyrase subunit A OS=Leptotrichia sp. oral taxon 212 GN=gyrA PE=3 SV=1
-------LDTLLIFTTKGKVFSMKVYEIPESGKQARGKLISNLIKSEKVSTVIKVR-NKKLFFITREGKVKKTDLTLFAN-NK--AGI---RALTLNDED
ELTYIG-T---NGKNEIFIATRNGVAIRFSE--VRSMRAAGVKGIDLR--DIVVAAAIIDPKLSVLTVTEEGYGKRTKLDEYRVQSRGGKGIINLKMNTG
K-IVGVKIVDE-TEVMLITSEGTLIRTRVDSISVIGRSTSGVRIMKVRNN--EKVASTVKIT--------------------------------------
------------
>tr|D0GPF9|D0GPF9_9FUSO DNA gyrase subunit A OS=Leptotrichia goodfellowii F0264 GN=gyrA PE=3 SV=1
-------LDTLLIFTTKGKVFSMKVYEIPEG-KQARGKLISNLIKEERVSTVIRVR-DKAIFFITKDGVVKKTDLTLFANINK--TGI---RALTLRDED
ELKFAGLT---SGKDEIFIATRNGISIRFC---VRVMRAAGVKGITLR---YVVAAVIINPELSVMTITEEGYGKRTALSEYKVQSRGGKGIINLKINTG
K-IVDVKIVD-KTEIMLITSEGTLIRTKVDTVSV-GRATSGVRIMKVRN-E-EKVASAVKIA--------------------------------------
------------
>tr|U2Q9A9|U2Q9A9_9FUSO DNA gyrase subunit A OS=Leptotrichia wadei F0279 GN=gyrA PE=3 SV=1
-------LDTLLIFTTKGKVFSIKVYEIPEG-KQARGKLIGNIINNEKVSTIIKVR-NKNLFFVTRNGVVKKSELTLFSNIMK--AGK---RAIRLNDDD
EVMFIGLT---SGEDEIFAATRNGIAIKFS---VRSMTAVGVRGITLR---KVVGAAIINSKMRILTITEEGYGKRTKLSEYRLQSRGGKGLINAKLNTG
K-IADVKIVR-NDEIMLITSEGTLIRTSINDITV-SRSATGVRIMKVRN-N-EKIASVVKIT--------------------------------------
------------
>tr|C7NEF8|C7NEF8_LEPBD DNA gyrase subunit A OS=Leptotrichia buccalis (strain ATCC 14201 / DSM 1135 / JCM 12969 / NCTC 10249 / C-1013-b) GN=gyrA PE=3 S
-------LDTLLIFTTKGKVFSIKVYEIPEG-KQARGKLIGNIINDEKVSTIIKVR-NKNLFFVTRNGVVKKSELTLFDNIKK--AGK---RAIRLNEDD
EVMFIGLT---SGEDEIFAATKNGIAIRFS---VRSMTAAGVRGINLR---KIVGAAIISSDARILTITEEGYGKRTKLLEYRLTSRGGKGIINAKLNTG
K-IVDVKIVK-DDEIMLITSEGTLIRTSVKDVSV-GRSATGVRIMKVRN-N-EKIASIVKIT--------------------------------------
------------
>tr|A0A0J7HLY5|A0A0J7HLY5_OENOE DNA gyrase subunit A OS=Oenococcus oeni GN=gyrA PE=3 SV=1
-------HDTLLFFSDQGKVYKMKGYEVPEYGRQAKGIPVINLLGDERVQAVINVRSKDFLFFTTKLGTIKRTAVSEFTN-RQ--SGL---RAINLRDDD
SLISVL-T---NG-QNIVIASHSGYAVSFAE--VRAMRASGVRGMNLR---KVVGADLLIPGDNVLIITEKGYGKQTAVEEYPIRGRGGKGYKTSNISNG
P-LAGLAVVSD-EDIMITTDSGVMIRFAAADVSITGRATLGVHVIKIEEG--SKVATLVKVE--------------------------------------
------------
>tr|A0A0A0M312|A0A0A0M312_9LACT DNA topoisomerase (ATP-hydrolyzing) (Fragment) OS=Oenococcus alcoholitolerans GN=Q757_00510 PE=4 SV=1
-------HDVLLFFSDQGKVYKMKGYEVPEYGRQAKGIPVINLLGDEHVQAVINVSSKDFLFFTTKFGIVKRTPVVDFSN-RQ--SGL---RAINLRPGD
SLINVL-T---HG-DNIIIASHRGYAVSFAE--VRQMRASGVKGMSLR---KVVGSDLLVPGNNVLVITENGYGKQTAVEEYPIRGRGGKGYKTVNVTNG
L-VSGLTVVSN-EDIMVTTNAGVMIRFDAKDVSKTGRATLGVRVIRIEKG--SKVATLTKVE--------------------------------------
------------
>tr|N0ATM7|N0ATM7_9BACI DNA gyrase subunit A OS=Bacillus sp. 1NLA3E GN=gyrA PE=3 SV=1
-------HDTILFFTNKGKVYRSKGYEIPEYSRTAKGLPIINLLEKEWVNAIIPVEDDWSLFFTTKQGVSKRSPLTSFAN-RN--NGL---IALNLREED
ELISVR-T---DG-KEIIIGTKKGMLIRFPE--VRSMRATGVKGINLD--DDVVGMEVLEDNTDILIVTQKGYGKRTPAVEYRVQGRGGKGIKTCNITNG
N-LISMKVVT--EDVMLITTGGVLIRMDVNDISSMGRNTQGVRLIRLGESH-DQVATVAKVA--------------------------------------
------------
>tr|A0A077J765|A0A077J765_9BACI DNA gyrase subunit A OS=Bacillus sp. X1(2014) GN=gyrA PE=3 SV=1
-------HDTILFFTNKGKVYRSKGYDIPEFSRTAKGIPIINLLGKEWVNAIIPVEDNWYLFFTTKDGISKRSPLSSFAH-RN--NGL---IALNLREGD
ELISVR-T---DG-KDIIIGTKKGMLIRFAE--VRSMRATGVKGITLD--DDVVGMEVLEENNDILIVTKNGYGKRTPASEYRIQGRGGKGIKTCHITNG
E-LVSVRTVTE-EDLMLITTSGVLIRIDVAGISQLGRNTQGVKLITLKESN-ESVATVAKVE--------------------------------------
------------
>tr|K6CFJ3|K6CFJ3_9BACI DNA gyrase subunit A OS=Bacillus bataviensis LMG 21833 GN=gyrA PE=3 SV=1
-------HDTILFFTNKGKVYRSKGYEIPEFSRTAKGIPIINLLGKEWVNAIIPVEDDWSLFFTTKEGISKRSPLTSFAN-RT--NGL---IALSLREGD
ELISVQ-T---DG-KHMIIGTKNGMLIHFPE--VRSMRATGVKGISLD--GDVVGMEVLEEDSDVLIVTKNGYGKRTPAAEYRIQGRGGKGIKTCHVTNG
N-LVSMRVVTE-EDLMLITTGGVLIRIDVAGISKMGRNTQGVKLISMKEDS-EFVATVAKVE--------------------------------------
------------
>tr|A0A090IQI6|A0A090IQI6_9BACI DNA gyrase subunit A OS=Bacillus thermoamylovorans GN=gyrA PE=3 SV=1
-------HDTILFFTNKGKVYKIKGYRIPEFSRTAKGLPIINLIEKEYINAMIPVQNESYLFFTTRQGISKRCPLSSFAN-RN--NGL---IAIHLREGD
ELISVR-T---DG-KHIIIGTKKGMLIRFVE--VRSMRASGVKGITLG--DDVIGMEILEEDQDVLVVTEKGYGKRTHASQYRIQNRGGKGIRTCNIQNG
Q-LVAMKSVSN-EDIMIITDNGIIIRMAVSGISRIGRNAMGVKLIKLTD-D-STVTAVAKVE--------------------------------------
------------
>tr|A0A0M0G912|A0A0M0G912_SPOGL DNA gyrase subunit A OS=Sporosarcina globispora GN=gyrA PE=3 SV=1
-------HDTILFFTNKGKVYRAKGYEIPEFSRTAKGIPIINLLGKEWVNAIIPVEDDWSLFFTTKQGISKRSPLSSFAN-RN--NGL---IALNLREDD
ELISVR-T---DG-KEIIIGTSHGMLIRFPE--VRSMRATGVKGISLS--GDVVGMEVLDDDSQILIVTKNGYGKRTPAEEYRVQGRGGKGIKTCNITNG
S-LVSMKAVTE-EDVMLITTGGVLIRMAVSDISTMGRNTQGVRLIRLNEDD-EAVSTVAKVE--------------------------------------
------------
>tr|A0A0M1NGH9|A0A0M1NGH9_9BACI DNA gyrase subunit A OS=Bacillus sp. FJAT-21352 GN=gyrA PE=3 SV=1
-------HDTLLFFTNKGKVYRSKGYEIPEYGRTAKGLPLINLLEKEWVNAIIPVKDDWYLFFTTRHGISKRTPLSSFAN-RN--NGL---IALGLREDD
ELISVR-T---NG-KQIIIGTKSGMMIRFPE--VRTMRAAGVKGISLG--NDVVGMEILEDDEEVLIVTKNGYGKRTSAEEYRIQSRGGKGIKTCNVTNG
E-LIAVKTVT-DEDLMLITAAGVLIRMEVEGISKTGRNTQGVKLIRLESAN-EYVSTVAIVG--------------------------------------
------------
>tr|A0A0M2SRV6|A0A0M2SRV6_9BACI DNA gyrase subunit A OS=Bacillus sp. SA2-6 GN=gyrA PE=3 SV=1
-------HDTILFFTNKGKVYRSKGYEIPEFSRTAKGLPIINLLGKEWVNAMIHIEDDWSLFFATKEGIVKRSPLTSFAN-RN--NGL---IALNLREGD
ELISVR-T---DG-KEIIIGTKNGLMIRFPE--VRTMRATGVKGISLS--DDVVGMEVLDESADILVVTKHGYGKRTPATEYRRQGRGGKGIKTCNITNG
S-LVTMKVVE--EDLMLITTGGVLIRIPVGGISITGRNTQGVKLISLNREN-EAVATVAQVD--------------------------------------
------------
>tr|A0A0M3RDH7|A0A0M3RDH7_9BACI DNA gyrase subunit A OS=Bacillus sp. FJAT-18017 GN=gyrA PE=3 SV=1
-------HNTILFFTNKGKVYKTKGYEIPEFSRTAKGIPIINLLGKEWVNAIIPVEDDWFLFFTTKEGISKRSPLSSFAH-RN--NGL---IALNLREGD
ELISVR-T---DG-KEIVIATKKGMQIRFAE--VRTMRATGVKGITLD--DDVIGMEVLEDDSEVLVVTSKGYGKRTDAAEYRIQGRGGKGIKTANVING
H-LVSMKTVT--EDLMLITTGGVLIRIPVDSISKVGRNTIGVKLINIK--N-ESVATVAKVE--------------------------------------
------------
>tr|Q7V124|Q7V124_PROMP DNA gyrase subunit A OS=Prochlorococcus marinus subsp. pastoris (strain CCMP1986 / MED4) GN=gyrA PE=3 SV=1
-------HDTLLLFSDRGVAYALPAYRVPMSSRTAKGTPSVQLLPREQITSLVSVDNECYLLMLTKAGFIKRTPLSAFSKVRS--NGL---IAINLEEGD
ALTWVRLS---TEGDSVLIGSSRGMTIHFRL--LRPLRARGVKSMNLK---DLVSMDVLSCGPWILVASAFGLGKRVPVTKFRLQKRAGMGLRAIKF-DD
S-LVGLKVLG-GEELLLVTERGVIVRTNADKISQQSRAATGVKLQRLDD-G-DHLSEVVLVP--------------------------------------
------------
>tr|A0A0A2BAY5|A0A0A2BAY5_PROMR DNA gyrase subunit A OS=Prochlorococcus marinus str. MIT 9401 GN=gyrA PE=3 SV=1
-------HDTLLLFSDRGVAYALPAYRVPMSSRTAKGTPSVQLLPREKITSLVAVDEDCFLLMLTKAGFIKRTSLSAFSKIRS--NGL---IAINLEDGD
ALTWVRLS---KEGDSVLIGSRTGMAIHFRL--LRPLRARGVKSMNLR---DLVSMDVLTSGPWVLIASAFGLGKRVPVAQFRLQKRAGMGLRAIKY-DD
V-LVCLKVLG-GEELLFVTEKGVIVRTNADKISQQSRAATGVKLQRLDE-G-DHLSEVVLVP--------------------------------------
------------
>tr|A0A091BK21|A0A091BK21_9GAMM DNA gyrase subunit A OS=Arenimonas oryziterrae DSM 21050 = YC6267 GN=gyrA PE=3 SV=1
-------HDTLLTFTSAGRVFWLKVYQLPDAGPNSRGRPIINWIP-EKVQAVLPVRADQFVFFATRDGTVKKTPLSEYSRPRA--SGI---WAINLDDGD
GLVDVQLT---NGERDIMLFASNGKAVRFDETEVRSMRATGVRGMRLVEEPVVVSLIVVDGEGDILTASQNGFGKRTPVSEYPRKGRGTQGVIAIATSNG
S-LVGAIQLTEQNEILLISDQGTLVRTRASEVSQVGRNTQGVTLMRVA-EG-EKLIAVESLD--------------------------------------
------------
>tr|A0A091B0Y7|A0A091B0Y7_9GAMM DNA gyrase subunit A OS=Arenimonas malthae CC-JY-1 GN=gyrA PE=3 SV=1
-------HDTLLTFTSTGRVFWLKVYQLPDAGPNSRGRPIINWIP-EKVQAVLPVRDDHFVFFATRDGTVKKTPLSEYSRPRS--TGI---WAINLDEGD
GLVDVQLT---DGNRNVMLFASNGKAVRFDESEVRPMRATGVRGMRLKEDQGVVSMIVVDGDGDILTASENGFGKRTAVSEFPRKGRGTQGVIAMQTSNG
E-LVGAIQLTEQHEILLISDQGTLVRTRAAEVSQVGRNTQGVTLMRVA-ED-EKLIAVERVD--------------------------------------
------------
>tr|F4BHA9|F4BHA9_FRACN DNA gyrase subunit A OS=Francisella cf. novicida (strain 3523) GN=gyrA PE=3 SV=1
-------HDTMLCFSSLGRVYWSKVYDFPVASRISKGRPINNILP-ERITAMMPISEGWYVFMATRLGRVKKVDLSEFARPRS--TGK---IAIGLNDGD
ELSYVALT---DGNKQIMMFSDAGKAIRFDESDVRAMRAAGVTGMRIHP--QIVSMLVTNPEGVVLAATENGYGKRTAVSEYRKTKRASQGVIAISTSNG
K-VVVAVLVENDEDIVMITDNGTLVRTSSDEVRECGRSAQGVRLINLR-NN-EKLISLKVVK--------------------------------------
------------
>tr|A0A0K1NM92|A0A0K1NM92_9BACT DNA gyrase subunit A OS=Prevotella fusca JCM 17724 GN=gyrA PE=3 SV=1
-------HQTMLFFTRKGRCYWMKCYDIPEGDKNSKGRAIQNMLSPDSVNAFLRIRDSHYVVFATKQGIVKKTSLRAYSR-RT--NGV---IAININEGD
EVVDVRLT---NGKNELIIADRNGRACRFD---IRTMRSTGVRGMRLD-G-DVIGMIVVNDNETVMVVSEEGYGKRSQVE-YRLTNRGGKGVKTLNVTTG
K-LVAIKNVT-ENDLMIINKSGIVIRMSVAECRVMGRATQGVRLINLAKKN-DVIASVCKVM--------------------------------------
------------
>tr|I4Z6J8|I4Z6J8_9BACT DNA gyrase subunit A OS=Prevotella bivia DSM 20514 GN=gyrA PE=3 SV=1
-------HQTMLFFTKNGRCYWMKCYDIPEGDKNSKGRAIQNMLSPDSVNAFLRIRDKHYVVFVTKKGLVKKTSLRAYSR-RT--NGV---IAININESD
EVVDVRLT---NGNDELIIANRNGRACRFH---VRTMRSTGVRGMKLD-C-DVIGMVVVNDNETVMVVSEEGYGKRSLVD-YRLTNRGGKGVKTLNITTG
K-LVAIKTVT-DNDLMIINKSGIVIRMAVAKCRVMGRATQGVRLINLSKKN-DTIASVCKVM--------------------------------------
------------
>tr|A0A098BYL7|A0A098BYL7_9PORP DNA gyrase subunit A OS=Porphyromonadaceae bacterium ING2-E5B GN=gyrA PE=3 SV=1
-------HNYMLLFTKKGKCYWLHVYEIPEGTKNSKGRAIQNLLNPDSVTAFVRVDNSNYLIFCTEQGIIKKTQLEAYSR-RQ--NGV---NAITIKEGD
QVISVRLT---NGNQHIILANRNGRAIRFD---VRPMRATGVKGMTLDDG-DVIGMICMSPENSILVVSEQGYGKRTKLNIYRITRRGGKGVKTLNITTG
K-LVAIKSVT-DNDLMIINKSGITIRMNISDIRIMGRATQGVRLINLEKRN-DQIASVCKVD--------------------------------------
------------
>tr|F5IUB4|F5IUB4_9PORP DNA gyrase subunit A OS=Dysgonomonas gadei ATCC BAA-286 GN=gyrA PE=3 SV=1
-------HNYMLLFTQKGKCYWLRVFDIPEGTKNSKGRAIQNLLNSDKVTAFVRVRNSHYLIFCTKEGVIKKTSLEAYSR-RQ--NGV---NAITIREED
KVIEVLMT---DGESEILLANRNGRAIRFN---VRVMRATGVRGMRLDDG-DVIGMLAMSKNETIMVVSEQGYGKRTNLNVYRITSRGGKGVKTLNITTG
K-LVSINSVT-ENDLMIINKSGITIRLKVSDIRTMGRATQGVRLINLGKRN-DEIASICKVE--------------------------------------
------------
>tr|A0A031FVR0|A0A031FVR0_9MICO DNA gyrase subunit A OS=Microbacterium oleivorans GN=gyrA PE=3 SV=1
-------HHWLLFFTTKGRVYRAKGYELPEAGRDAKGQHVANLLAPEDVAQILDIRAE-YLVLATRDGKIKKTALTEYDT-RQ--GGI---IAIRLRGGD
ELVSAM-----DSTDDLLLVSRLGMSLRFTD--LRPMRTEGVKGMSFR-G-DLLSASVVRDDSFVFVVTEGGFAKRTSVDQYRVQGRGGLGIKVAKLHRG
E-LAGGLIVND-DEVLVVLASGKVVRSAVAEVPA-GRDTMGVVFARPDD-D-DRILAIARNG--------------------------------------
------------
>tr|S3AUR0|S3AUR0_9MICO DNA gyrase subunit A OS=Microbacterium sp. oral taxon 186 str. F0373 GN=gyrA PE=3 SV=1
-------HHWLLFFTTKGRVYRSKAYEVPEAGRDAKGQHVANLLAPEEIAQILDIRAQ-YLVLATRDGKIKKTFLSEYDT-RQ--GGI---IAIRLRGGD
EVVSAL-----DDTDDILLISRQGMSLRFTE--LRPMRTEGVKGMSFR-G-DLLSASVAKDDAYVFVVTEGGYAKRTAVDQYRLQGRGGLGIKVAKLNRG
D-LAGGLIVGD-DEVLVVLASGKVVRSAVAEVPA-GRDTMGVVFARPDD-D-DRILAIARNS--------------------------------------
------------
>tr|W0ZAK1|W0ZAK1_9MICO DNA gyrase subunit A OS=Microbacterium sp. C448 GN=gyrA PE=3 SV=1
-------HHWLLFFTNRGRVYRAKAYELPEAGRDAKGQHVANLLAPEEIAQVLDIRAT-HLVLATRGGLVKKTRLTEYDT-RQ--GGI---IAISLREGD
ELESAL-----EADDDILLISRHGMSLRFTD--LRPMRTAGVKGMSFR-N-DLLSASVAPQGHYVFVVTDGGYAKRTAVAEYRGQSRGGLGIKVAKLSRG
V-LAGGLIVGD-DEVLVVLASGKVVRSSVAEVPA-GRNTMGVVFARPGD-D-DRIIAIARNG--------------------------------------
------------
>tr|U2XAE5|U2XAE5_9MICO DNA gyrase subunit A OS=Microbacterium sp. TS-1 GN=gyrA PE=3 SV=1
-------HHWLLFFTTKGRVYRTKAYELPEAGRDAKGQHVANLLAPEEIAQILDIRAQ-YLVLATRDGKVKKTALTEYDT-RQ--GGV---IAIRLRGGD
ELVSAL-----DEGDDILLITRKGMSLRFAD--LRPMRTEGVKGISFR-D-DLLSASVVRDEGYVFVVTDGGYAKRTSVDQYRTQSRGGLGIKVAKLNRG
V-LAGGLIVST-DEVLVVLASGKVVRSSVAEVPA-GRDTMGVVFARFGD-D-DRILAIARNG--------------------------------------
------------
>tr|F6IUI0|F6IUI0_LACPE DNA gyrase subunit A OS=Lactobacillus pentosus MP-10 GN=gyrA PE=3 SV=1
-------HDVLLFFTNAGKVYRMKAYEIPEYGRTAKGIPVINLLGNEKIQAVVNVTSDNYLFFTTVNGVVKRTPVQEFAN-RS--NGL---KAITLKDDD
ELIGVT-T---DG-QNVIIGTHDGYAVSFDE--VRSMRASGVRGIRLR---DVIGFDVLKPDSNVFIITEKGYGKQTPAADYPIKGRGGKGIKTANVTNG
H-LAGLTTVDQ-EDIMVMTNQGVMIRFNIATVSQTGRATLGVRLIRLDDD--GKVATMAKVD--------------------------------------
------------
>tr|A0A0H4R1N4|A0A0H4R1N4_9LACO DNA gyrase subunit A OS=Lactobacillus ginsenosidimutans GN=gyrA PE=3 SV=1
-------HDRLLFFTNTGKVYRTKGYEVPEYGRTAKGIPVINLLNEEKIQTIINVGDNSFLFFVTKYGTVKRTAVNDFAN-RH--SGL---RAIALRDED
ELNNVF-T---DG-KVIFIGTHKGYAVTFSE--VRPMRASGVRGIKLR---EVVGSSILSSDQEVLTISENGYGKRTAATEYPVKGRGGKGIKTANVTNG
P-IAGVAAVSD-EDIMLVTNTGVMIRFDVENVSQTGRATLGVRLIKVDDK--AFVSTMALIA--------------------------------------
------------
>tr|A0A0R1QSA4|A0A0R1QSA4_9LACO DNA gyrase subunit A OS=Lactobacillus mindensis DSM 14500 GN=FD29_GL000017 PE=4 SV=1
-------HDRLLFFTNAGKVYRIKGYEVPEYGRTAKGIPVINLLNEEKIETVINVDDSSFLFFVTKYGTVKRTPVNDFAN-RH--SGL---RAITLKDED
ELNNVF-T---DG-KVIIIGTHKGYAVTFSE--VRPMRAAGVRGIKLR---EVIGSSIAKEGQEILTISEKGYGKRTAVEEYPVKGRGGKGIKTANVTNG
P-IAGLSVVDT-EDIMLITDKGVMIRFEVQSVSQTGRATLGVRLIKVDDD--SIVSTMTKVA--------------------------------------
------------
>tr|A0A0R1IXY5|A0A0R1IXY5_9LACO DNA gyrase subunit A OS=Lactobacillus tucceti DSM 20183 GN=FC72_GL000699 PE=4 SV=1
-------HDRMLFFTNTGKVYRTKGYEVPEYGRTAKGIPVINLLNEEKIQTVINVGENSFLFFVTKYGTVKRTPVTDFAN-RH--SGL---RSITLKDGD
ELTNVF-T---NG-KVIFIGTHKGYAVTFRE--VRPMRAAGVRGIKLR---EVVGSSIVEPGQEVLTISEKGYGKRTKVEEYPIKGRGGKGIKTANVTNG
P-IAGVTSVND-EDIMLITDKGVMIRFDVESVSQTGRATLGVRLIKVDDN--SIVSTMAKIE--------------------------------------
------------
>tr|C3JD53|C3JD53_POREA DNA gyrase subunit A OS=Porphyromonas endodontalis (strain ATCC 35406 / BCRC 14492 / JCM 8526 / HG 370) GN=gyrA PE=3 SV=1
-------HATLLLFTTKGRCFWLPVYKIPEGAKSTKGRAIQNILNADRITACIRIKASHYLVFATLQGMIKKTPLEAYSN-RS--KGV---FAIKLNEGD
SVVSVRLT---NGKTEILLANKGGRAIRFP---VRSMRTTGVRGMILDGG-DIVGMVALK-KETILVVSECGYGKRTTLDSYRITNRGGKGVKTMQITTG
S-LVDFRSVT-ELDLMIINRSGVAIRMPMSSINVIGRATQGVKLINLSSRG-DEIASVCIVA--------------------------------------
------------
>tr|A0A0A2G4R1|A0A0A2G4R1_9PORP DNA gyrase subunit A OS=Porphyromonas gingivicanis GN=gyrA PE=3 SV=1
-------HATLLLFTTKGRCHWLHVYEIPEGAKNTKGRAIQNILDPDRITACIRIKNSHYLIFATQQGLVKKTLLEAYSR-RS--KGV---NAINLNEGD
RVVTVRLT---NGNAEILLANRNGRAIRFH---VRAMRATGVRGITLDD--DVVGMVALK-EESLLVVSEGGYGKRSLLDTYRTTNRGGKGVKTMQITTG
R-LVDFRAVT-ELDLMIINKSGVVIRMPMESISTIGRATQGVRLINLASRE-DEIASVCSVA--------------------------------------
------------
>tr|D1AVF2|D1AVF2_STRM9 DNA gyrase subunit A OS=Streptobacillus moniliformis (strain ATCC 14647 / DSM 12112 / NCTC 10651 / 9901) GN=gyrA PE=3 SV=1
-------LDTLMVFSDKGKVYSIKVYEIPEVSKQARGKLIGNIIEEEKISVIIP--DNRDLIFITRNGIAKKTKISEFKTINR--NGK---IAISFKDDE
DEVKIT-G---SEKDEIFISTKGGMAVRFKE--IRSMRAAGVRAIKLN---DVVSADVIYTEMSVLSVTSLGIGKKTLLSEYNIIKRGGKGVKNY--ESK
E-ESYSDENSENMELVAISTTGTVIRIKIKDLPVVGRNSKGVKIQSLKY-K-EYLVSADRVA--------------------------------------
------------
>tr|R6BXE1|R6BXE1_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:510 GN=gyrA PE=3 SV=1
-------HHYLNFFTNQGRVYRLKAYEIPEAGRTARGVAIINLLNPEKITAMIPISDNKNLFMITKKGIAKKTPLMEYSN-RK--NGL---AAINLREDD
ELIEVK-T---DK-SEIFLVTKFGMCIRFLE--VRATRSMGVIGMNLS---GIVGMQLASQGDSLLIASENGLGKRTPMDEFTVQKRGGKGVKCYKITTG
E-VVGVKAVND-NEIMMITTEGIIIQLRVQEISTLGRITSGVKLINLKDG--VKVAQIAKVR--------------------------------------
------------
>tr|R6ELP4|R6ELP4_9FIRM DNA gyrase subunit A OS=Firmicutes bacterium CAG:65 GN=gyrA PE=3 SV=1
-------HHYLNFFTNMGRVYRLKAYEIPEAGRTARGTAIVNLLQPEKITAMIPIHDDKNLFMVTKTGIVKKTPLMEFSN-RK--NGL---TAINLREED
ELIEVK-T---DS-SEIFLVTKQGMCIRFQE--VRATRSMGVIGMNLS---GIIGMQLQTQGSDLLIVSENGMGKRTNMDEFTVQKRGGKGVKCYKIVTG
D-VVGAKAVND-NEIMMITTEGIIIQLRVQDISTLSRITSGVKLINLDEG--VKVAQIAKVR--------------------------------------
------------
>tr|A0A0F4JU05|A0A0F4JU05_9ACTN DNA gyrase subunit A OS=Streptomyces sp. NRRL S-495 GN=gyrA PE=3 SV=1
-------HNWILFFTNKGRVYRAKGYELPDAGRDARGQHVANLLAPEHIAQVMAVRKP-YLVLATRAGLVKKSQLKDYDS-RS--GGL---IAINLRQDD
ELIGAE-----SAADDLLLVSKKAQSIRFTD--LRPTRTSGVKGMSFR-D-DLLSMNVVRPDTYVFTATDGGYAKRTGVDEYRVQGRGGYGTKAAKIVRG
S-LVGALVVDS-DEIMAITLSGGVIRTRVSEVRE-GRDTMGVQLINLGK-R-DAVVGMARNA--------------------------------------
------------
>tr|D0TCA4|D0TCA4_9BACE DNA gyrase subunit A OS=Bacteroides sp. 2_1_33B GN=gyrA PE=3 SV=1
-------HATLLFFTAKGKCYWLKVFEIPEGAKNAKGRAIQNLLNPDKVQAFIRVKNSHYLLFCTKKGVIKKTLLEAYSR-RQ--NGV---NAITLREDD
GLIQVCMT---NGNNEVIIANRNGRAIRFH---VRVMRASGVKGMTLDDN-DVVGMICIKDKETVLVVSEQGYGKRSSI-DYRITNRGGKGVKTINITTG
K-LVAIKNVT-ENDLMIINKSGIAIRMKVADLNVIGRATQGVRLINLEKRN-DEIASVCKVL--------------------------------------
------------
>tr|R7J8Z7|R7J8Z7_9PORP DNA gyrase subunit A OS=Parabacteroides sp. CAG:409 GN=gyrA PE=3 SV=1
-------HATMMFFTSKGRCFWLPVYQIPEGTKNAKGRAIQNLLNADKVQAFIRVKNSHYLLFCTKKGIIKKTCLEAYSR-RQ--NGV---NAITLREDD
GLIQVCMT---NGDREVLIANRNGRAIRFH---VREMRASGVRGMTLDDG-DVVGMVCIKDKETTLVVSEQGYGKRSHI-DYRITNRGGKGVKTLNITTG
K-LVAFLNVT-ENDLMIINKSGITIRTKVSDLSIIGRATQGVRLINLGKRN-DEIASVCKVL--------------------------------------
------------
>tr|E6PRJ3|E6PRJ3_9ZZZZ DNA gyrase subunit A OS=mine drainage metagenome GN=gyrA PE=3 SV=1
-------HAMLLCFSNRGRVYWMKVYEAPQGGRGSRGRPLVNLFP-EKITVVLPVK-DHFVFMATARGTVKKTPLSAFANRRT--AGI---IACGLDDDD
YLVGVAIT---DGQHDVMLFSDSGKAVRFDE-DVRPMRARGVRGMNLE--DGVIAMLVAEDSQSVLTATENGFGKRTSIVEYTRHGRGTKGMIAIQTSNG
K-VVAACLVRADDEIMLITDTGVLVRTRVAEIRELGRATQGVTLIALD-DK-AQLIGVQRVA--------------------------------------
------------
>tr|A0A0K6HZ10|A0A0K6HZ10_9BURK DNA gyrase subunit A OS=Thiomonas bhubaneswarensis GN=gyrA PE=3 SV=1
-------HDMLLCFSNRGRVYWMKVYESPMGGRGSRGKPLVNLFP-EKITTVLPVK-QHYVFMATARGTVKKTPLTAFANRRT--AGI---IAVGLDDDD
YLIGAAIT---DGQHDVMLFSDAGKAVRFDE-DVRPMRARGVRGMQLE--ADVIALLVAEDTQSVLTATENGYGKRTSITEYTRHGRGTKGMIAIQTSNG
R-VVAACLVRPKDEIMLITDTGVLVRTRVEEIREMGRATQGVTLIALD-AK-AQLIQVQPVV--------------------------------------
------------
>tr|A0A0Q7UU42|A0A0Q7UU42_9MICO DNA gyrase subunit A OS=Agromyces sp. Root1464 GN=ASD23_05085 PE=4 SV=1
-------HHWLLFFTNMGRVYRAKAYEIQEAGRDAKGQHVANLLEPEQIAEILDIRAQ-YLVLATRDGLVKKTELTAYDT-RS--RGV---IAINLREGD
ELVSAM-----GVHDEILLVSKKGMSLRFEE--LRPMRTSGVKGMSFR-G-DLLEASVVAAARYVFVVTEGGYAKRTAVDQYRLQNRGGLGIKVAKLSRG
D-LAGALIVGD-DEVLVVLASGKVVRSDVAEVPA-GRDTMGVVFAKFAN-D-DRIIAIAKNS--------------------------------------
------------
>tr|A0A0Q5HFC6|A0A0Q5HFC6_9MICO DNA gyrase subunit A OS=Leifsonia sp. Leaf325 GN=ASF62_15800 PE=4 SV=1
-------HHWLLFFTNMGRVYRAKAYEIQEGGRDAKGQHVANLLEPEQIAQVLDIRAQ-YLALATRDGLVKKTALEEYDT-RS--RGV---IAVKLREGD
ELVSAM-----DQGDEILLVSRKGMSLKFAS--LRPMRTSGVKGMDFR-G-DLLSASVVRAPASVFIVTEGGYAKRTSVDQYRVQNRGGLGIKVAKLSRG
D-LVGSLIVAE-DEVLVVLASGKVIRSDVAEVNR-GRDSMGVIFAKFAD-S-DRIIAIAKNT--------------------------------------
------------
>tr|B0CDP0|B0CDP0_ACAM1 DNA gyrase subunit A OS=Acaryochloris marina (strain MBIC 11017) GN=gyrA PE=3 SV=1
-------HDSVLFFSDRGVVYCLRAYQIPVSSRTARGVPLVQLLPREKITSVIPVSEDEYLVMMTAGGFIKKTALAAFSNIRA--NGL---IAISLEEGD
LLRWVRLT---RAEDSIVIGSRRGMSIHFRA--LRPLRTRGVRAMRLR---DFIGMDILSSGPWVLVITTNGFGKRVPVAQFRLQNRAGKGVTATKFLPD
Q-LAALRIVN-EDELMLVTSRGIVIRQAVTDISSQSRAATGVRVQRLDE-D-DYIAAVALVP--------------------------------------
------------
>tr|K9Q432|K9Q432_9CYAN DNA gyrase subunit A OS=Leptolyngbya sp. PCC 7376 GN=gyrA PE=3 SV=1
-------HDHVLFFTDRGVVYSLHAYQIPESSRTARGLPAIQLLPKEKITSMIRVSEDEYLVMLTQNGYIKKTTLSAFARIRS--NGL---IAISLEDGD
QLNWVRLA---RQEDSIIVASSEGMAIHFQA--LRPLRTRGVRAMKLK---DLVSMDIVSAGPWVVAVTTKGFGKRVQVGRFRLQNRAGVGLRAIKF-GD
R-LASLRIVH-GNELMLVTSRGIMIRQAVESISLQSRNATGVRVQRLDK-E-DAIVAVALVP--------------------------------------
------------
>tr|A0A073IPK4|A0A073IPK4_9BACT DNA gyrase subunit A OS=Synergistes jonesii GN=gyrA PE=3 SV=1
-------HRTLYLFTNKGRVFGVRGFSLPE-PKTGKGKLVGTIITKEKAVAIKDSNGEKFVFFVTKQGTAKRLPVEELEGLTR--AGR---RVLGISEGD
DIARVRFT---SGGCDLLLTTATGQTLRVNE--FRPQRAQGMRGIRLD---AVVGCDVVAE-RQVLFISEGGIGKRTSYDEFTQHHRGGYGVRAM--STG
P-LVGAWGVQEDEEIIVITGKGRMVRIGAKEISSLSRSATGYMIVTLDD-G-DTVADISIVK--------------------------------------
------------
>tr|Q5ZVM3|Q5ZVM3_LEGPH DNA gyrase subunit A OS=Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513) GN=gyrA PE=3 
-------HDTLLCFSNHGKLYWLKAYQLPQASRASRGRPIINILP-EEINAMLPVRDGSYVFMATKKGTVKKVPLNAFSRPRS--NGI---IAVDLEEDD
SLVGVDIT---DGARDIMLFTDAGKVIRFDESKVRPMRARGVRGIRVEKQA-VKSLVVVD-GGTILTATENGYGKRTHIDEYRVSGRGGQGVISIQVTNG
K-VVRSLQVTDNDEAMLITDKGTLVRFKVNELSVIGRNTQGVRLINVS-SG-EAVVGMQKIV--------------------------------------
------------
>tr|K2BL93|K2BL93_9BACT DNA gyrase subunit A OS=uncultured bacterium (gcode 4) GN=gyrA PE=3 SV=1
-------HDTILCFSNHGKVYWLKSYQVPQASRIARGKPIINLLP-ERINALLPVKEDQYVFMATEKGTVKKVSLDHFSRPRN--SGI---IAIELHEGD
RLVGVALT---DGKQDVMLFSNAGKAIRFPEDKVRSMRAAGVRGISLHEQK-IISLIIVK--GNILTATENGYGKCTAIEEYRVTSRGGQGVISIQISNG
N-VVGATQVTRGEEVMLITDRGTLIRTRVDEISVVGRNTQGVRLINLS-EE-EKLTQLQRIA--------------------------------------
------------
>tr|W2V5Y6|W2V5Y6_9GAMM DNA gyrase subunit A OS=Legionella oakridgensis RV-2-2007 GN=gyrA PE=3 SV=1
-------HDTLLCFSSHGKVYWLKVYELPMASRISRGKPIINVLP-EAINAMMPVREGYSVFMATSKGTVKKVPLDAFSRPRS--NGI---IAIDLDEDD
CLIGAGIT---DGSKDIMLFSDAGKVIRFDENLVRTMRARGVRGIRMGAQA-LISLVVVH--GTILTATEFGYGKRTAIEEYRVTGRGGQGVISIQVNNG
K-VVRALQVDDNDEAMLITDKGTLVRFRVNELSIIGRNTQGVRLINVS-AG-ERVVGMQRIE--------------------------------------
------------
>tr|W6M8C4|W6M8C4_9GAMM DNA gyrase subunit A OS=Candidatus Competibacter denitrificans Run_A_D11 GN=gyrA PE=3 SV=1
-------HDTVLCFSNRGKVYWKKVYELPQAGRTARGKPIVNLLP-ERINAVLSVRDDHYVFFATTNGTVKKTPLSEYSRPRP--SGI---IAIDLRDGD
QLVNVELT---DGQRDVMLFSDAGKAVRFTETDVRDTRAYGVRGIRLGEQK-VIALIVVD-G-TVLTVTENGFGKRTPAAEYARHGRGGQGVIAIQTSNG
R-VIGAVQVENDHEIMLISDGGTLVRTRVGEISVVGRNAQGVKLISLQ-GE-EKLAGVEKIE--------------------------------------
------------
>tr|G9ENM0|G9ENM0_9GAMM DNA gyrase subunit A OS=Legionella drancourtii LLAP12 GN=gyrA PE=3 SV=1
-------HDTLLCFSNHGKLYWLKAYQLPLASRISRGRPIINILP-EEINAMLPVREGFYVFMATRNGTVKKVPLNAFSRPRS--NGI---IAVDLDEND
RLVGVDIT---DGTRDIMLFTDAGKVIRFDESKVRPTRARGVRGIRIEEQA-VISLIVAH--GTILTATEHGYGKRTDIDEYRVSGRGGQGVISIQVTNG
K-VVRSVQVNDSDEAMLITDKGTLVRFRVSELSIIGRNTQGVRLINVS-SG-ELVVGMQKIE--------------------------------------
------------
>tr|A0A0B0H7X5|A0A0B0H7X5_SOVGS DNA gyrase subunit A OS=Solemya velum gill symbiont GN=gyrA PE=3 SV=1
-------HDTILCFTSRGRVYWLKVYDLPQAGRTARGRPMNNLLP-ERVNAVLPVRENLFVFMATSSGVVKKTSLEAFSRPRA--SGI---IAVELRDDD
KLIGVDIT---DGSMDVMLFSTEGKAMRFSESQVRSMRATGVRGIKLGKHQ-VTSLIIAR-GSRILSASENGYGKCTPVEDYPQKGRGGMGVISLKTSNG
K-QVGAVIVDEDDEIMLITDGGTLVRTRVSDVSVTGRSAQGVKLISLS-AK-EHLIGIEPVV--------------------------------------
------------
>tr|A0A0A8UVV2|A0A0A8UVV2_LEGHA DNA gyrase subunit A OS=Legionella hackeliae GN=gyrA PE=3 SV=1
-------HDTLLCFSNHGKLYWLKAYELPLASRISRGKPIVNILP-ESINAMLPVREGYFVFMATKHGTVKKVPLEAFSRPRS--SGI---IAVDLNEDD
RLVGVDIT---DGTKDIMLFTDAGKVVRFDENLVRPMRARGVRGIRLHEQS-VISLVVAK--GTILTATENGYGKRTHIEEYRVSGRGGQGVISIQVSNG
K-VVRAAQVEETDEAMLITDKGTLVRFRVAELSIIGRNTQGVRLINVS-SG-EHVVGMQRIE--------------------------------------
------------
>tr|A0A0K1EIW4|A0A0K1EIW4_CHOCO DNA gyrase subunit A OS=Chondromyces crocatus GN=gyrA PE=3 SV=1
-------HSHVFFFSDTGKVFVKKVYEIPQAARNAKGRAIVNFV-PEKVAAVMSVPEGRFVVTVTRRGQIKKTALLEYENYRD--KGI---IGVRIEESD
QLLVAA-T---DGTQELVIATRTGMSIRFSE--VRATRTMGVKAIELE---DVVGMGTSGDRDRVLAVCERGYGKQTPIEEFRKQSRGGKGVILI--SNG
P-VVGVAMVCTTDEVLLVTDKGQMIRTKVSEIRETSRNAQGVRLMNVDD-G-ERVVAIEAFA--------------------------------------
------------
>tr|A0A0D8L8E7|A0A0D8L8E7_MORMO DNA gyrase subunit A OS=Morganella morganii GN=gyrA PE=3 SV=1
-------HDTILCFSNKGKLYWLKVYQLPEASRGARGRPIINILPEERITAIL--PEGKFVFMATASGTVKKTSLQDFSR-RN--AGI---IAVNLNEGD
ELIGVDLT---DGSNEVMLFSADGKVVRFAEDAVRAMRATGVRGIRLG---DVVSLIIPRGEGEILTVTENGYGKRTAEAEYPTKSRATQGVISI--SNG
K-VVGAIQVG-DDQIMMITDAGTLVRTRVSEVSIVGRNTQGVTLIRTGE-E-EKVVGLQRLA--------------------------------------
------------
>tr|M0ITP1|M0ITP1_9EURY DNA gyrase subunit A OS=Haloferax mucosum ATCC BAA-1512 GN=gyrA PE=3 SV=1
-------HDDLLCFTNHGQVYQLKAYQVPEMSRTARGKSAVNLLDDEEITAVVN--IDGYLTMVTRDGYIKRTSVDKFQNILS--TGI---IATKLDEGD
ELADVE-T---DGTRDLVIGTEQGMSIRFDE--VRAMRARGVRGINLT---DVAGVAAIDEHSWVLTVTENGYGKRTDLDAYRAQSRNGKGLIDI--NNG
P-VCAINTVGEGDHLVVMSDEGQILRTPVEDISTVGRNTMGVIVMDIES-G-DAVASVDVIP--------------------------------------
------------
>tr|M0DGJ3|M0DGJ3_9EURY DNA gyrase subunit A OS=Halogeometricum pallidum JCM 14848 GN=gyrA PE=3 SV=1
-------HDYLLYFTNHGQVYKLKTYQVPEMSRTARGKSAVNLLEDEEITSVVN--TEKYLTMVTRNGYVKRTSVEKFQNILT--TGI---IATKLDDGD
ELADVE-T---DGTRDLILASRDGMSIRFDE--VRAMRARGVRGMKLT---DLVGVAAVDEHNWVLTVTENGYGKRTDIGDYRRQSRNGKGLIDI--NNG
P-VCAMETVGYGDHLFVMSQSGQMLRTPVDDVSTVGRNTMGVIVMKMDA-G-DHVASVDVHQ--------------------------------------
------------
>tr|V4ZTU5|V4ZTU5_9ARCH DNA gyrase subunit A OS=uncultured archaeon A07HB70 GN=gyrA PE=3 SV=1
-------HDYLLCFTTHGQVYQLKTYQVPEMGRTARGKSAVNVLDDEEMAAVVNTA-GGYLTMATRGGRVKRTSVDEFGNILS--TGI---RAISLEEGD
ELVDVEVT---DGESDLVLATARGMTIRFDE--VRPMRARGVRGIRLE---SVVGVAAADEHDWLLTVTANGYGKRTDIDSYRRQSRNGKGLIDI--NNG
R-ACSIETVSQGDHVLVMSEAGQVIRTPVENISTVGRNTMGVTVMDLTA-D-DSVAAIEVVD--------------------------------------
------------
>tr|E4NLL7|E4NLL7_HALBP DNA gyrase subunit A OS=Halogeometricum borinquense (strain ATCC 700274 / DSM 11551 / JCM 10706 / PR3) GN=gyrA PE=3 SV=1
-------HDYLLYFTNHGQVYKLKTYQIPEMSRTARGKSAVNLLEDEEITAVVN--TDKYLTMATQNGYVKRTSVEKFQNILT--TGI---IATKLDEDD
ELADVE-T---DGSHDLVLASRDGMAIRFDE--VRAMRARGVRGMKLE---DLVGVAAVDEHNWVLTVTQNGYGKRSDIERYRRQSRNGKGLIDI--NNG
P-VCAMETVGYGDHLFVMSESGQILRTPVEDISTVGRNTMGVTVMDMDE-G-DHVASVDVYN--------------------------------------
------------
>tr|E4T2N1|E4T2N1_PALPW DNA gyrase subunit A OS=Paludibacter propionicigenes (strain DSM 17365 / JCM 13257 / WB4) GN=gyrA PE=3 SV=1
-------HNTMLFFTSKGKCYWLKVYDIPEGSKNSKGRAIQNMLNNDKVNAFIRVKKSHYLIFATKNGVIKKTSLEAYSR-RQ--NGV---NAITIREDD
QVIQVRLT---DGNSEVLMANRNGRAIRFH---VREMRATGVRGMTLDDG-DLVGMICVNKNENIMVVSQQGYGKRTLLDVYRVTNRGGKGVKTMNITTG
K-LVTIKNVT-ENDLMIINKSGITIRLKVADFRVMGRATQGVRLINLEKRN-DEIASVCKVL--------------------------------------
------------
>tr|D7JDY7|D7JDY7_9BACT DNA gyrase subunit A OS=Bacteroidetes oral taxon 274 str. F0058 GN=gyrA PE=3 SV=1
-------HNYMLFFTQKGRCYWLKVYDIPEGSKTSKGRAVQNMLNADKINAFIRVKSKHYLVFCTQNGIIKKTCLEAYSR-RQ--NGV---NAITIREND
QVIQVRLT---DGNSEIVIANRQGRAIRFH---VREMRATGVNAMAIDAN-DVVGMVAVADTETVLVVSEKGYGKRSQLDIYRVTNRGGKGVKTMNITTG
K-LVSIKLVD-SNDIMIINKSGMAIRMHVSDIRVMGRATQGVRLINLERRN-DEIAAVCKVD--------------------------------------
------------
>tr|A0A0A2EHF4|A0A0A2EHF4_9PORP DNA gyrase subunit A OS=Porphyromonadaceae bacterium COT-184 OH4590 GN=gyrA PE=3 SV=1
-------HNYMLFFTQKGKCYWMKVYDIPEGSKNSKGRAIQNMLNPDKINAFIRVKTKHYLVFCTKNGIIKKTRLEAYSR-RQ--NGV---NAITIREDD
QVIQVRLT---DGNSEIVIANREGRAIRFH---VREMRATGVIGMALDDK-DVIGMVSVSDRDTILVVSEKGYGKRSLLDIYRITNRGGKGVKTINITTG
K-LVSIKLVD-NNDIMIINKSGMTIRMHVSDIRVMGRATQGVRLINLEKRN-DEIAAVCKVD--------------------------------------
------------
>tr|A0A098CN40|A0A098CN40_9LACT DNA gyrase subunit A OS=Lactococcus garvieae GN=gyrA PE=3 SV=1
-------HDHLLFFTNLGRVYRMKGYEIPEYGRAAKGLPIVNLLKDEKIQTIINVVEERYLFFTTRKGLVKRTNTQQFAN-RT--NGL---KALNLREGD
ELINVL-T---SG-ENIIIGTHNGFSVRFEE--VRDMRATGVKGVSLR---GVVGTAIVHDEQEVLVISEKGLGKRTIASEYPVKGRGGKGIKVMNITTG
K-LAGLTAIND-EDIMVITDTGVVIRTSVDNISQTGRAAQGVKIMRLDDD--AQIVTFALVE--------------------------------------
------------
>tr|F5REI4|F5REI4_METUF DNA gyrase subunit A OS=Methyloversatilis universalis (strain ATCC BAA-1314 / JCM 13912 / FAM5) GN=gyrA PE=3 SV=1
-------HDYILCFSNRGRVYWLKVYEVPEGSRNSRGKPIVNLFP-EKITAVLPVK-NHYIFMATGRGTVKKTPLTDFSNPRK--AGI---IAVDLDEGD
ALIGVAIT---DGSDDIMLFSDAGKAVRFAE-DVRPMRARGVRGMMLE--DGVICMLVSKNELSVLTATENGFGKRTRVTEYPKHGRGTKGVIAIQTSNG
G-VVGAVLVETTDEIMLISTGGVLIRTRVADIREMGRSTQGVTLINLD-DG-TRLAGLEKVI--------------------------------------
------------
>tr|A0A0K2G694|A0A0K2G694_9BACT DNA gyrase subunit A OS=Nitrospira moscoviensis GN=gyrA PE=3 SV=1
-------HDTLLFFTDAGKVYWLKVHEIPEAGRAAKGKALVNLLAGEKVTATLPVK-DRFVVMATKKGLVKKTELSAYSN-RQ--GGI---IALSLEGGD
KLISVH-T---DG-REILLGTKQGITIRFKE--VRPMRAYGVKGITLE--NEVIGMETITPTTAILTVTEGGYGKRTPVGEYRVQGRGGKGIISVKTTNG
P-AVGFLQVRG-DEIMLMAAQGKVLRCKVDDIREVGRNTQGVRVLDLEGEE-DRVVGVARLA--------------------------------------
------------
>tr|B2KAM8|B2KAM8_ELUMP DNA gyrase subunit A OS=Elusimicrobium minutum (strain Pei191) GN=gyrA PE=3 SV=1
-------HATILMFTTRGRVFSLRAYEIPEGNRLSKGKAIVNLLQNEKITSAVAIEGETYLTMCTRFGLIKRVELGDFANIRK--SGI---IAIGLEDGD
VLTSVQ-T---HGKSDLIIATRDGKAIRFDE--IRAMRAKGVRGIRLG---DVVGMEHALKGPDVLSVCENGYGKRTEFTEYRKQNRGGSGTITI--TNG
K-VVGIKLVDESKDLMVITENGMAVRIRCEEIRSVGRNAQGVRLVKLAE-S-DKIARIAPVI--------------------------------------
------------
>tr|G2Z0N6|G2Z0N6_FLABF DNA gyrase subunit A OS=Flavobacterium branchiophilum (strain FL-15) GN=gyrA PE=3 SV=1
-------HQYMLFFTQKGKCFWMRVYEIPEGNKTAKGRAIQNLINSDKVKAYICTQQNNYLIMVTKKGIMKKTLLEQYSR-RV--NGV---AAITIREDD
ELLAAELT---NGESQILVAVKSGKLVRFE---TRPMRASGVRGITLQD--DVIGMVAVNDNSEILVVSENGYGKRSSL-DYRITNRGGKGVKTLNITTG
N-LVSINSVT-ADDLMIINKSGLTIRLAVEDLRVMGRATQGVKLINLKG-K-DSIAAVTKVM--------------------------------------
------------
>tr|A0A095UYR2|A0A095UYR2_9FLAO DNA gyrase subunit A OS=Flavobacterium aquatile LMG 4008 GN=gyrA PE=3 SV=1
-------HNYLLIFTQKGKCYWMRVYEIPEGTKASKGRALQNLINPDKVKAFICTQKSHYVVMATKKGQVKKTSLEKYSK-RV--NGV---AAITIKEDD
ELLAAELT---NGQSQILIAVKSGKLVRFE---TRPMRASGVRGITLRA--DVIGMVSVDEDTQLLVVTENGYGKRTKLEVYRITNRGGKGVKTLNITTG
A-LVSINTVT-ADDLMIINKSGLTIRMDVSTLRVMGRATQGVRLINIKG-N-DSIAAVTKVM--------------------------------------
------------
>tr|A0A0E3TBP5|A0A0E3TBP5_FLAPS DNA gyrase subunit A OS=Flavobacterium psychrophilum GN=gyrA PE=3 SV=1
-------HQYMMFFTQKGKCYWMRVYEIPEGSKTAKGRALQNLINSDKVKAFICTQTSHNLIMVTKKGMVKKTSLDKYSK-RV--NGV---AAITIKEGD
ELLSAQLT---DGNSQIIIAVKSGKLLRFE---TRPMRASGVRGIRLKE--DVIGLVSVNDNSEILVVAENGYGKRSSL-EYRITNRGGKGVKTLNITTG
Q-LISINTVT-ADDLMIINKSGLTIRMAVEDLRVMGRATQGVKLINLKG-K-DSIAAVTKVM--------------------------------------
------------
>tr|A0A0B2A0Y2|A0A0B2A0Y2_9MICO DNA gyrase subunit A OS=Microbacterium mangrovi GN=gyrA PE=3 SV=1
-------HHWLLFFTNKGRVYRTKAYEVPEAGRDAKGQHVANLLAPEEIAQILDIRAT-YLVLATRGGLVKKTRLTEYDT-RQ--GGV---IAIKLRATD
EVVSAL-----NEDDDLLLISRHGMSLRFTE--LRPMRTAGVKGMSFR-D-DLLSASVATPGSSVFVVTEGGYAKRTDVDQYRTQSRGGIGIKVAKLNRG
V-LAGGLIVQD-DEVLVVLASGKVVRSAVAEVPA-GRDTMGVVFARPDD-D-DRILAIARNT--------------------------------------
------------
>tr|A0A0F0LTA4|A0A0F0LTA4_9MICO DNA gyrase subunit A OS=Microbacterium ginsengisoli GN=gyrA_1 PE=3 SV=1
-------HHWLLFFTTKGRVYRAKGYEVPEAGRDAKGQHVANLLAPEQVAQILDIRSP-YLVLATRSGLVKKTRLGEYDT-RQ--GGV---IAIKLREGD
EVTSAL-----DESDDVLLISRHGMSLRFTD--LRPMRTEGVKGMAFR-D-DLLSASVVHDEGFVFVVTEGGYAKRTDVDQYRVQSRGGLGIKVAKLHRG
D-LAGGLIVGD-DEVLVVLASGKVVRSAVAEVPA-GRDTMGVVFARPDD-D-DRILAIARNG--------------------------------------
------------
>tr|A0A0M8MIL1|A0A0M8MIL1_9MICO DNA gyrase subunit A OS=Microbacterium chocolatum GN=gyrA PE=3 SV=1
-------HHWLLFFTNKGRVYRAKGYEVPEAGRDAKGQHVANLLAPEEIAQILDIRAT-YLVLATRSGLVKKTRLTEYDT-RQ--GGI---IAIRLRGGD
ELVSAL-----DEDDDILLISRHGMSLRFTA--LRPMRTEGVKGMDFR-D-DLLSASVARDDAFVFVVTEGGYAKRTAVDQYRTQNRGGLGIKVAKLHRG
D-LAGGLIVSV-DEVLVVLASGKVVRSAVAEVPA-GRDTMGVVFARPDD-E-DRILAIARNG--------------------------------------
------------
>tr|G4SWG5|G4SWG5_META2 DNA gyrase subunit A OS=Methylomicrobium alcaliphilum (strain DSM 19304 / NCIMB 14124 / VKM B-2133 / 20Z) GN=gyrA PE=3 SV=1
-------HDTILCFSSLGKVYWLKVYQLPVASRASRGKPFVNLLP-ENINALLPVRADKFIFMATANGTVKKTPLPEFERQRT--NGK---IAIDLREED
ALVGVAVT---DGQQNILLFSTDGKAVCFNEEDVRSMRAAGVRGIRLQPQK-VISLIVSA-EGTVLTITENGYGKRTHLKEFVRKGRGGQGVISIQTSNG
N-VVGAVLVSERDEIMLITNGGTLVRTRVDEISIVGRNTQGVTVIRLD-KN-EKVVGVDRIE--------------------------------------
------------
>tr|G0A476|G0A476_METMM DNA gyrase subunit A OS=Methylomonas methanica (strain MC09) GN=gyrA PE=3 SV=1
-------HDTILCFSSRGKVYWLKVYELPVASRASRGKPFVNLLP-EKINAMLSVRADKYVFMATASGTVKKTPLTEFAYQLA--KGK---IAIDLRDND
MLVGVALT---DGQQNVMLFNSDGKAVCFNETDVRPMRAAGVRGMRLQEQK-IISLIIST-EGTVLNITENGYGKRTRIEEFTQHKRGGQGLIAIQTSNG
A-VVGAVLVNDTDEIMLITNAGTLVRTRVNEISVVGRNTQGVTVIRLD-KG-EKVVGVDRIE--------------------------------------
------------
>tr|H8GN71|H8GN71_METAL DNA gyrase subunit A OS=Methylomicrobium album BG8 GN=gyrA PE=3 SV=1
-------HDTILCFSSLGKAYWLKVYQLPIASRTSRGKPFVNLLP-EKINAMLPVRENKYIFMATTAGTVKKTPLIEFERQRT--GGK---IAIDLQEGD
RLVGCAIT---DGSQNVLLFSSDGKAVCFNETDVRPMRAAGVRGMRLAEQQ-VISLIIGT-EGTVLNITENGYGKRTRLEEFPCHNRGGQGVIAIQTSNG
A-VVGAVLVNAHDEIMLITDGGTLVRTPVDGISVLSRNTQGVTIIRLD-KK-EKVIGVDRIE--------------------------------------
------------
>tr|R6VV14|R6VV14_9BACT DNA gyrase subunit A OS=Prevotella sp. CAG:474 GN=gyrA PE=3 SV=1
-------HQTMLFFTKKGRCYWLKCYEIPEYDKSSKGRAIQNLLNPDAVNAFLRLRNSHYVVFATANGTVKKTCLEAYSR-RA--NGV---NAIHITEGD
EVVDVRLT---NGHNELILANRNGRAVRFN---IRTMRSTGVRGMRLD---DVIGMIVVNDKESVMVVSENGYGKRSQVA-YRITNRGGKGVKTLAITTG
R-LVAIKNVT-ENDLMIINKSGITIRLAVADVRIMGRATQGVRLINLAKKN-DIIASVCKVM--------------------------------------
------------
>tr|A0A0C2JPL0|A0A0C2JPL0_9ACTN DNA gyrase subunit A OS=Streptomonospora alba GN=gyrA PE=3 SV=1
-------HNWILFFTNKGRVYRIKAYELPEAARDARGQHVANLMEPEEITQVMALRAP-YLVLATRQGLVKKSRLEDFDS-RS--AGI---IAINLRD-D
ELISAR-----FATDDLLLISGDAQAIRFPE--LRPMRTSGVIGMRFQ-G-ELLSMDVVREPADVLVATEGGYAKRTPADQYPVQNRGGKGVLTAKVVRG
R-LVGALMVSEKDEVFAITSAGGVIRTHCSQVKQ-GRATMGVRLMNLDE-G-NQVVAVARNA--------------------------------------
------------
>tr|A0A0N0TKB4|A0A0N0TKB4_9ACTN DNA gyrase subunit A OS=Nocardiopsis sp. NRRL B-16309 GN=gyrA PE=3 SV=1
-------HHWILCFTNQGRVYRTKAYELPEAARDARGQHVANLLPPEEIAQIMALRAP-YMVLATREGLVKKSRLEDFDS-RA--AGI---IAINLRE-D
ELIAAR-----FPDDDLLLISSDAQAIRFSE--LRPMRTSGVIGMRFL-G-DLLSMDVIRPSTDVLVTTENGYAKRTPSEQYPVQNRGGKGVLTAKVVRG
K-LVGALMVDEVDEVFAITSAGGVIRTGAEEVKQ-GRTTMGVRLMNLDK-G-NKIVAVARNA--------------------------------------
------------
>tr|A0A0Q1A4G6|A0A0Q1A4G6_9BACT DNA gyrase subunit A OS=Candidatus Cloacimonas sp. SDB GN=APR54_12895 PE=4 SV=1
-------HAYILFFTNLGKCHWLKVHKVPKVGRLARGKAIVNLL-REKIEAYVSVRLPHYVTMVTKKGVVKKSELKAFSHPRI--NGI---IAIKLMEGD
QLIDAI-T---EGNNDIILATSHGYANRFNE--VRSMRSQGVRGISLR---DVVAMVVVKR-GTLLAISENGYGKRSEISNYKKTRRGSKGVITL--TNG
E-LIALIEVVDNDDLMIVTRAGMIIRQAVNKITVIGRNTQGVKLIELNK-D-DKVYDITRIP--------------------------------------
------------
>tr|A0A0M6W6M3|A0A0M6W6M3_9ENTR DNA gyrase subunit A OS=Candidatus Providencia siddallii GN=gyrA PE=3 SV=1
-------HDTIICFSNRGRLYWMKIYQLPESTRYSRGRPIVNLIP-ERITAILPVPDGYYVFMATANGIVKKTALRDFGRPRS--SGI---VAVKLNDGD
ELIGVNLT---NGVNEVMLFSAKGKVVRFAENTVRPMRSIGIRGIKLF--LEVVSLIIPSN-GHILTVTEKGYGKRTEEIKYPIKSRATQGVISIKVSNG
N-VIGAIQVDESDQIMIITDVGTLVRIRVSEVNVIGRNTQGVTLIKTA-EN-EKVVGLQKVN--------------------------------------
------------
>tr|A0A084CMQ9|A0A084CMQ9_9GAMM DNA gyrase subunit A OS=Candidatus Photodesmus blepharus GN=gyrA PE=3 SV=1
-------HDSILCFSTRGKAYRLKVYQLPLASRIARGKPIVNILP-ERITAILPVSSEKFIFMSTNDGIVKKTPLDQFANVRS--NGL---IAINLHDGD
LLINVDIT---NGESDVMLFSKMGKVVRFNEKKVRAMRAAGIRGIKLA--DNVVSLIVPSN-GNILTVTQNGYGKRTELSEYPTKSRATQGVVSIKISNG
S-VVGAVQVGENDEIMMITDAGTLVRTRVSEISQIARNTQGVTLIRTN-ED-EKVVALQRII--------------------------------------
------------
>tr|A0A0Q5EFD8|A0A0Q5EFD8_9MICO DNA gyrase subunit A OS=Plantibacter sp. Leaf314 GN=ASF68_11150 PE=4 SV=1
-------HHWLLFFTTKGRVYRAKAYELQEAGRDAKGQHVANLLAPEEIAEILDIRAT-YLVLATHDGLVKKTALSEYDT-RS--GGI---IAINLREGD
ELTSAL-----ENDSDILLVSRKGMSIRFTE--LRPMRTSGVIGMHFR-E-DLLSASVLPSEAFVFVVTEGGFAKRTNIDQYRGQNRGGLGIKVAKLNRG
T-LAGALIVDG-DEVLVVLASGKVVRSAVAEVPA-GRDTMGVVFARFAE-S-DRIIALAKNS--------------------------------------
------------
>tr|V5C915|V5C915_9GAMM DNA gyrase subunit A OS=Methyloglobulus morosus KoM1 GN=gyrA PE=3 SV=1
-------HDTILCFSSRGKVYWLKVYQLPVASRASRGKPFVNLLA-EKINAILPIKDNKFIFMATSSGTVKKTPLNEFERQRA--NGK---IAIDLREDD
TLVGVAVT---DGQQNVLLFASSGKANCFNESDVRPMRASGVRGMRLQD--QIISLII-GTEGMVLNITENGFGKRTRVEEFTQHKRGGQGMIAIQTSNG
A-LVGAVLVNEHDEIMLITDGGILVRTPVDGISVVGRNTQGVRIIRLD-TG-EKVIGVDRIE--------------------------------------
------------
>tr|B9D3C2|B9D3C2_CAMRE DNA gyrase subunit A OS=Campylobacter rectus RM3267 GN=gyrA PE=3 SV=1
-------HDTLMFVTDRGQLYWLKVYKIPEGSRTAKGKAVVNLIQPEKIKAIIPTTQSKSLAFFTKNGIVKRTNLSEFKNIRS--IGV---RAISLDEND
ELVTALVEGENLIEKMLFIVTKKGMCLKFK---VRQMRARGVTGIKFKA--DVVGAAVIENAQEVLSVSQKGIGKRTTADEYRLTNRGGKGVICMKLTTG
D-LIG-VVVD-EQDLMALTSSGKMIRVDMQSIRKAGRNTSGVIVVNVD-----DVVSIAKCP--------------------------------------
------------
>tr|I1DYS8|I1DYS8_9GAMM DNA gyrase subunit A OS=Rheinheimera nanhaiensis E407-8 GN=gyrA PE=3 SV=1
-------HDTILCFSNRGRLYWMKVYQLPLASRTARGKPIVNLLP-ERINAIL--PENKYVFMATANGTVKKTSLTEYSR-RS--NGI---IAVNLNDGD
RLIGVGIT---DGNSEIMLFSDDGKVVRFAEDQVRSMRATGVRGIKLR---GVVSLIIPNGSGPILTVTENGYGKRTALQEYPAKSRATQGVVSI--SNG
L-VVGAVQVN-LDEIMMISNKGTLVRTRVNEVSEVGRNTQGVILIRTAD-N-EKVVGVEKID--------------------------------------
------------
>tr|R4I011|R4I011_9ENTR DNA gyrase subunit A OS=Serratia symbiotica str. 'Cinara cedri' GN=gyrA PE=3 SV=1
-------HDTILCFSSLGRLYWMKVYQLPEVSCAARGRPIVNLLP-ERITAIL--PKGRYVFMATARGTVKKTALTDFSR-RS--AGI---IAVHLNAGD
KLIGVDLT---DGNNEVMLFSTSGKVVRFPENQVRSMRAIGVRGINLG---GVISLIVPRASGDILTVTQNGFGKRTAITAYPTKSRATQGVISI--SNG
Q-VVGAVQVE-IDQIMMITDAGTLVRTRVSEVSLVGRNTQGVRLIRTVE-E-ENVVGLQRVA--------------------------------------
------------
>tr|A0A0H5Q627|A0A0H5Q627_SYNPZ DNA gyrase subunit A OS=Synechococcus sp. (strain WH8103) GN=gyrA PE=3 SV=1
-------HDTLLLFSDRGVSYALPAYRVPQCSRTAKGTPVVQLLPREAITSLIPVSDDMDLLMLTRGGFIKRTRLSAFSNIRS--NGL---IAINLEEGD
ALRWVRLA---VPGDSVLIGSNAGMTIHFRL--LRPLRARGVRSMNLR---DLVSMDVLPVGPWVLVASASGLGKRVPVTQFRLQKRAGMGLRAMKF-DD
A-LVGLRVLG-GEEVLLVSEKGVIVRTSADAIPQQSRAATGVRLQRLDK-G-DRLSEVVLVP--------------------------------------
------------
>tr|A0A0A2C638|A0A0A2C638_PROMR DNA gyrase subunit A OS=Prochlorococcus marinus str. PAC1 GN=gyrA PE=3 SV=1
-------HDSLLLFSDRGISYALPAYRVPQCSRTAKGTPIVQLLPREAITSLLSVSDENYLLMLTRGGYIKRTPLSAFSKIRA--NGL---IAIGLGDGD
ALTWVRLA---ESGDSVLIGSKNGMTIHFRL--LRPLRARGVKSMNLK---DLVSMDVLSTGPWVLVASGSGLGKRVPMTQFRLQKRAGMGLRAIKF-GD
E-LVGLRVLG-GEELLLVSERGVIVRTSADKISQQSRAATGVRIQKLDN-G-DKLSEVVLVP--------------------------------------
------------
>tr|A0A0G8AXH1|A0A0G8AXH1_9SYNE DNA gyrase subunit A OS=Candidatus Synechococcus spongiarum 142 GN=gyrA PE=3 SV=1
-------HDTLLLFSDRGIVYALPAYKVPIASRTAKGSPIVQLLPREDITSLLALPDDQHLLMLTQAGFIKRTPLSAFANIRV--NGL---IAIHLESGD
ALRWVRLA---QVGDSVLIGSRSGMAIHVPI--LRSMRARGVRAMALR---DVIGMDVLVGVPWVLVASAHGRGKRVAMEEFPLQARAGMGRRALKF-GD
A-LISLRILG-AEEVLLVSKQGVIVRLQADQISQQSRAATGVRLQKLGA-E-DRLAEVVLVP--------------------------------------
------------
>tr|A0A084CL37|A0A084CL37_9GAMM DNA gyrase subunit A OS=Candidatus Photodesmus katoptron GN=gyrA PE=3 SV=1
-------HDSILCFSTRGKTYQLKVYQLPLASRIARGKPIINILP-ERITAILPVSSNKFVFMATRNGIVKKTSLQKFSNVRS--NGL---IAINLHDDD
LLIGVDIT---NGNSNAMLFSKFGKVVRFKEEKVREMRAAGIRGMKLV--GNVVSLIVPAN-GNILTVTQNGYGKRTELFEYPIKGRATQGVVSIKISNG
S-VVSAVQVEESDEVMIITNTGTLVRTRVSEISQVGRNTQGVILIRTT-EH-ENVVGLQC-I--------------------------------------
------------
>tr|A0A0R1XYB3|A0A0R1XYB3_9LACO DNA gyrase, A subunit OS=Lactobacillus composti DSM 18527 = JCM 14202 GN=FC83_GL001848 PE=4 SV=1
-------HDTVLFFTNHGKVYRSKGYEIPEYGRTAKGIPVINLLGDERIQTMVHIPREHYLFFITRLGVVKRTLVGEFDN-RK--SGL---RAVTLRDED
ELSNVL-T---DG-ANILIGTHLGYAVSFRE--IRAMRAAGVRGIRLR---KVVGSDVLTPDKDVFVISEKGYGKRTPAKEYPIKGRGGKGIKTANITNG
P-LAGVTTVKN-EDILLMTNTGVLIRFEAENISTTGRATLGVRLIRVDDD--ALVSTMAKVD--------------------------------------
------------
>tr|A0A0R2CS97|A0A0R2CS97_9LACO DNA gyrase, A subunit OS=Lactobacillus rennini DSM 20253 GN=FC24_GL000235 PE=4 SV=1
-------HDMLLFFTNTGKVYRAKGYEIPEYGRTAKGIPVINLLEKERIQTVINVAAEHYLMFTTRKGVTKRTAVAEFRN-RS--NGL---KAITLKDGD
ELMNVC-T---DG-QNIIIGTHLGYAVSFAE--VRAMRATGVRGIRLR---HVVGAAILAPDSNVLVISENGYGKQTPATEYPIKGRGGKGIKTVNVTNG
P-LAGLTTVAD-EDLMLITNTGIVIRFHVKDVSQTGRATLGVRLIRVDDD--AKVATMTKVA--------------------------------------
------------
>tr|H3NIJ4|H3NIJ4_9LACT DNA gyrase subunit A OS=Facklamia languida CCUG 37842 GN=gyrA PE=3 SV=1
-------HDSLLFFTNFGKVYRTKGYDIPQYGRASKGLPIVNLLNDEFVKEVVNSRKESYLTFVTKFGVVKRTAVKDYDN-RT--NGL---IAINLRPGD
ELINVL-T---DG-QKILIASRQGYAVSFNE--IRVIRAAGVKGMTLR---EVIGAILLEADKQVLVVTENGYGKRTVIDQYAIRNRGGKGVKTANLSSG
Q-LVAVASVSA-DDLLIMTNEGIVIRIHAATISSSSRDTLGVKVIRLDEG--TTVDKVVVIQ--------------------------------------
------------
>tr|W1Q1D6|W1Q1D6_ABIDE DNA gyrase subunit A OS=Abiotrophia defectiva ATCC 49176 GN=gyrA PE=3 SV=1
-------HDSLLFFTNKGKVYQSKGYDIPEYGRTAKGIPVVNLLNEEYVKEIIVLHEDQYLFFVTKNGIVKRSDVSAYAN-RN--NGL---IALNMREDD
ELINVL-T---NG-QNIIIGSHNGYAMTFAE--ARIMRATGVRGMKLR---GVVGAAVLNPESNVLVVTERGYGKQTPASEYAVKNRGGKGIKTSNISSG
Q-LAGIVSTED-EDLMVMTDQGVVIRFNIASISVTSRATLGVKMIRLDDG--AKVSSITKIM--------------------------------------
------------
>tr|E4KME1|E4KME1_9LACT DNA gyrase subunit A OS=Eremococcus coleocola ACS-139-V-Col8 GN=gyrA PE=3 SV=1
-------HDTLLFFTNQGKVYEKRGFEIPEYGRTAKGLPIINLIKDEEVKAMISISHEKYLFFVTKTGTVKRTLSSEYYN-RN--NGL---IALNLKEDD
SLVAVM-T---DG-KPIIIGTHEGNAISFLE--VRAMRATGVRGVRLR---DVVGADIMVEGSDVLVITDKGYGKRTPVEQYSIKNRGGLGVKTSNISSG
K-LAGLLVVEH-EDILVMTNQGVAIRMKVEGISQSSRATLGVRMIRLDQE--AVVSSITTIL--------------------------------------
------------
>tr|K1LE72|K1LE72_9LACT DNA gyrase subunit A OS=Facklamia hominis CCUG 36813 GN=gyrA PE=3 SV=1
-------HDTLLFFTNYGKVYQAKGYDIPQYGRASKGLPLVNLLKDEQVLEIINVRKQRYLFFVTKNGRVKRTSVEEFYN-RV--NGL---IAMGLNEGD
ELRHVL-T---DE-SNIILASHEGYAVSFDQ--VRVMRAAGVKGMSLR---GIIGADILKEDHQILVVSENGYGKKTPVEEYALRYRGGKGVKTAKISSG
K-LAAMLCIEH-EDLMIMTNTGIVIRICVKDISVSSRDTLGVKVIRLDEE--AIVEKMVAIG--------------------------------------
------------
>tr|R5KJ81|R5KJ81_9BACT DNA gyrase subunit A OS=Prevotella sp. CAG:1124 GN=gyrA PE=3 SV=1
-------HNTMMFFTQKGRCYWLKCYEIPEGAKNSKGRAIQNLLNSDSIKAFLRLRNSHYVVFATKRGLIKKTSLEAYSR-RA--NGV---IAINVLEGD
EVVGVRLT---NGRNELLMADRNGRAVRFN---VRAMRSTGVRGMKLD---DVVGMVVVNRVETIMVVSENGYGKRSQVE-YRMTNRGGKGVKTLNITTG
R-LVAIKVVT-ENDLMIINKSGILIRLKVSDCRVMGRATQGVRLINLTKKN-DVISSVCKVM--------------------------------------
------------
>tr|A0A0D0I8G4|A0A0D0I8G4_9BACT DNA gyrase subunit A OS=Prevotella sp. P5-119 GN=gyrA PE=3 SV=1
-------HNTMMFFTKKGRCYWLKCYEIPEGNKSSKGRAIQNLLNSDSVNAFLRLRNSHYVVFATKNGLIKKTLLEAYSR-RA--NGV---IAINIQEGD
EVVGVRLT---NGHNELVLANRNGRAVRFD---VRAMRSTGVRGMRLD---DVVGMVVVNKEETIMVVSENGYGKRSLVE-YRVTNRGGKGVKTLGITTG
R-LVAIKVVT-ENDLMIINKSGIVIRLSVKECRVMGRATQGVRLINLTKKN-DVIASVCKVM--------------------------------------
------------
>tr|J3TWW9|J3TWW9_9ENTR DNA gyrase subunit A OS=secondary endosymbiont of Ctenarytaina eucalypti GN=gyrA PE=3 SV=1
-------HQTILLFSSRGRMYWMKVYQLPEASRGSRGRPIVNLLP-ERITAIL--PDGCHVFMATASGTVKKTSLIEFSR-RS--AGI---IAVKLNDGD
ELIGVDLT---NGSNEVMLFSAYGKVVRFPENQVRSMRATGVRGISLA---GVVSLIVPHGNGSLLTVTQHGYGKRTAEVEYPTRSRATQGVISI--SNG
G-VVGAVQVN-CDQIMMITDAGTLVRMRVSEVSIVGRNTQGVTLIRAPK-D-ESVVGLQRVV--------------------------------------
------------
>tr|A0A0A8BVZ6|A0A0A8BVZ6_9BURK DNA gyrase subunit A OS=Pandoraea pulmonicola GN=gyrA PE=3 SV=1
-------HDTILCFSNRGRVYWIKVYEVPQGSRNSRGRPIVNMFP-EKINVVLPVK-DRFVFMATSLGTVKKTPLAAFSRPLK--KGI---IAVNLDEGD
VLIGAAIT---DGAHDVMLFSDAGKAVRFDENDVRPMRARGVRGMQLE--DGVIALLVAENQQSVLTATENGYGKRTSITEYTRHGRGTKGMIAIQTSNG
R-VVAATLVEPDDEIMLITTGGVLIRTRVSEIREMGRATQGVTLISLD-EG-TTLSGLQRIV--------------------------------------
------------
>tr|D4G7N6|D4G7N6_RIEPU DNA gyrase subunit A OS=Riesia pediculicola (strain USDA) GN=gyrA PE=3 SV=1
-------HENILCVSNFGRIFSIKVYQLPESSRFSLGKPIVNFLSDEKITSIFSLKKGNYILIATLMGLIKKISMDFLTKARK--SGI---IIINLNKRD
EVIAMDSV---KKRSEIILFTSSAKAIRFSE-SVRLTRSMGVMGVKIQ---ELVSMIIVEK---ILTITENGYGNRTKESEYLKKSRFIRGVSVIKNDNG
K-IVGAIQVE-KDQVVIFTNYGILIRILVKDISVFKRNTKGIILIRKIN-D-QVVSGIYRVS--------------------------------------
------------
>tr|W0DLU7|W0DLU7_9GAMM DNA gyrase subunit A OS=Thioalkalivibrio thiocyanoxidans ARh 4 GN=gyrA PE=3 SV=1
-------HDTILCFSSRGRVYWIKVYELPQGSRVARGKPIVNLLP-ERINAILPVREDRFVFMVTAGGTVKKTPLTDFSRPRT--AGI---IAVDLREGD
YLVDVALT---DGSQEVMLVTSAGKAVRFPETDVRAMRACGVRGVRMDEHR-VIALLIVG-EGSALFASEFGYGKRTGFDEFPVHRRGGQGVIAIQCANG
M-LIGAARVLDDQEVMLITDAGTLVRTAVAQIPLIGRNTQGVRLIRLS-EG-EKLAELARVE--------------------------------------
------------
>tr|R9IZR6|R9IZR6_9FIRM DNA gyrase subunit A OS=Lachnospiraceae bacterium 3-1 GN=gyrA PE=3 SV=1
-------HHYLMFFTSTGKVYRMKAYEIPEAGRTARGTAIINLLQPEKITAVIPIKDDHYLFMATKNGIVKKTPVTDYAN-RK--KGL---AAINLREED
ELIEVK-T---DN-KDMILVTRYGQCIRFHE--VRSTRSMGVIGMNLS---RVVGMQMNTQGEYLLIASEKGLGKLTRMDEFTPQNRGGKGVKCYKITTG
N-IVGVKAVNE-NEIMMITTEGIIIRMKVEGISVLGRVTSGVKLMNLDE-D-ITVASIAKVR--------------------------------------
------------
>tr|R7QWG4|R7QWG4_9FIRM DNA gyrase subunit A OS=Roseburia sp. CAG:182 GN=gyrA PE=3 SV=1
-------HHYLMFFTNMGKVYRMKAYEIPEAGRTARGTAIINLLQPEKITAVIPIREGNYLFMATKNGIVKKTPITDYAN-RK--TGL---AAINLRDDD
QLIEVK-T---DN-KDIILVTKFGQCIRFHE--VRSTRSMGVIGMNLT---GVVGMQMNTQGDALLIVSEKGLGKATLMTEFTPQNRGGKGVKCYKITTG
N-IIGIKAVND-SEIMLITTEGIIIRMKVEDISLLGRVTSGVKLINMDD-D-ITVASIAKVR--------------------------------------
------------
>tr|N2AYB0|N2AYB0_9FIRM DNA gyrase subunit A OS=Eubacterium plexicaudatum ASF492 GN=gyrA PE=3 SV=1
-------HHYLMFFTNMGRVYRMKGYEIPEAGRTSRGTAIINILQPEKITALIPIHEGEYLFMATRKGIVKKTPILEYAN-RK--TGL---AAISLREDD
ELIEVK-T---DN-KDIILVTKYGQCIRFNE--VRGTRSIGVIGMNLA---SVVAMQLDTQGEMLLAVSEKGMGKCTLMDEFTVQNRGGKGVKCYKITTG
N-IIGVKAVND-NEIMMITTEGIIIRMPVAGISVLSRVTSGVKLMNLEP-D-VKVASLTKVR--------------------------------------
------------
>tr|R5TDJ7|R5TDJ7_9FIRM DNA gyrase subunit A OS=Roseburia sp. CAG:50 GN=gyrA PE=3 SV=1
-------HHYLMFFTNTGKVYRMKAYEIPEASRTARGTAIINLLQPEKITAVIPIKDGWYLFMATKKGIVKKTAITDYAN-RK--TGL---AAITLREDD
ELIEVK-T---DD-QDIFLVTKYGQCIRFHE--VRSTRSMGVIGMSLA---GVVGMQLNTQGEHLLIVSERGLGKRTSIDEFTAQNRGGKGVKCYKITTG
N-LVGVKAVND-NEIMIINTEGIIIRMKVSDISILGRVTSGVKLINMEN-D-VTVASITKVK--------------------------------------
------------
>tr|R6NN64|R6NN64_9FIRM DNA gyrase subunit A OS=Roseburia sp. CAG:45 GN=gyrA PE=3 SV=1
-------HHYLMFFTNSGKVYRMKAYEIPEAGRTARGTAIINLLQPEKITAVIPIKEGEYLFMATKNGIVKKTPICEYAN-RK--TGL---AAINLRDDD
ELIEVK-T---DN-KDIILVTKYGQCIRFHE--VRSTRSMGVIGMNLA---SVVGMQLNTQGDALMIVSEKGLGKCTLMSEFSPQNRGGKGVKCYKITTG
N-IIGVKAVND-NEIMLITTEGIIIRIPVNGTALLGRVTSGVKLINVND-G-VTVASMAKVK--------------------------------------
------------
>tr|A0A0M6WW24|A0A0M6WW24_9FIRM DNA gyrase subunit A OS=Roseburia inulinivorans GN=gyrA PE=3 SV=1
-------HHYMMFFTNTGRVYRMKAYEIPEAGRTARGTAIINLLQPEKITAVIPIKEGHYLFMATKNGIVKKTPITDYAN-RK--TGL---AAITLREDD
ELIEVK-T---DN-QDIFLVTKYGQCIRFNE--VRSTRSMGVIGMNLT---GVVGMQMESQGESLMIVSEKGLGKCTLASEFTAQNRGGKGVKCYKITTG
N-IVGVKAVND-DEMMLITTEGIIIRIKVSDTALLGRVTSGVKLMNLAD-D-VTVASIAKVR--------------------------------------
------------
>tr|D4KZY2|D4KZY2_9FIRM DNA gyrase subunit A OS=Roseburia intestinalis XB6B4 GN=gyrA PE=3 SV=1
-------HHYMMFFTNTGRVYRIKAYEIPEASRTARGTAIVNLLQPEKITAVIPIREGHFLFMATKKGIVKKTPITDYAN-RK--TGL---AAISLREDD
ELIEVK-T---DN-QDVFLVTKYGQCIRFKE--VRKTRSMGVIGMNLT---GVIGMQMQSQGDALMIVSEKGLGKCTLISEFTTQNRGGKGVKCYKITTG
N-IVGVKAVND-NELMLITTEGIIIRIKVSDTTLLGRITSGVKLINLDE-N-VTVASIAKVR--------------------------------------
------------
>tr|A0A0H5BX80|A0A0H5BX80_9ENTR DNA gyrase subunit A OS=Candidatus Westeberhardia cardiocondylae GN=gyrA PE=3 SV=1
-------HDTILLFSNQGKVYWMKVYQLPESNRTSRGRPIVNLLP-EKITTILPVKEASHIFMATANGTVKKTSFNEFIHPRN--TGL---IAINLNKGD
ELIGVDLT---NGNSDIMLFSSYGKVVRFSEKQVRNMRVIGVQGINLK--KGVVSLIIPKN-SPILTITKNGYGKRTKQSEYPKKSRATQGVISIKVTNG
K-VVSAVQADNSNQIMIITDAGTLVRIRVSEINIVSRNTQGVRLIRTI-DN-EHVVGLQRII--------------------------------------
------------
>tr|A0A0J8H0J3|A0A0J8H0J3_9GAMM DNA gyrase subunit A OS=Gammaproteobacteria bacterium Q1 GN=gyrA PE=3 SV=1
-------HDTILCFSDRGRLYWLRVFQLPLATRTARGRPIVNLLP-ERISAIL--PDDKYIIMATANGTVKKTSLMEYSR-RA--NGI---IALNLNDGD
HVIGVDIT---NGDSEIMLFSNEGKVVRFSEQQVRSMRATGVRGMKFA---GVVSMIVPQGEGQVLTVTENGFGKRTPLLEYPAKSRATQGVVSI--SNG
A-VVGAVQVN-NDEIMLISDKGTLVRTRVSEVSSVGRNTQGVRLIRTGE-N-EHVVGLQQID--------------------------------------
------------
>tr|U3U9K1|U3U9K1_9ENTR DNA gyrase subunit A OS=Candidatus Pantoea carbekii GN=gyrA PE=3 SV=1
-------HDSILCFSSRGRLYWMKVYQLPEASRSARGRPIVNLLP-ERITAILPVRKGFNILMSTAKGTVKKTALQEFSRPRS--TGI---IAINLHKND
ELIGVALT---NGSDEVMLFSAAGKVVRFSEATVRATRASGVRGIKLA--ENVVSLIVPRA-GAILTVTQNGYGKRTINKAYPLKSRATQGVISIKVTNG
P-VVGAVQVVDNDQIMMITNTGTLVRTRVSEVSIVGRNTQGVILIRTA-EN-ENVVGLQRVV--------------------------------------
------------
>tr|F6DCK6|F6DCK6_THICA DNA gyrase subunit A OS=Thioalkalimicrobium cyclicum (strain DSM 14477 / JCM 11371 / ALM1) GN=gyrA PE=3 SV=1
-------HDMLLCFSNRGKLYWKKTWQLPLAGRGARGKPIVNVFP-ESISSILPVSEQHSVFMATKHAIVKRVKLIDFSRPRA--NGI---IALDLLDGD
ELVGTALT---NGEQDVMLFADGGKAIRFNENDVRVMRARGVRGMKLAE--QVMSMQIAQANTLILTATEHGFGKCTPVEDYSTINRGGQGVISIKTSNG
K-VVSAVSVTTDQEVVLITNKGTLVRTRVAEISVVGRNTQGVKLINVG-KD-EWVVGIAVVN--------------------------------------
------------
>tr|L8Y1F2|L8Y1F2_9GAMM DNA gyrase subunit A OS=Wohlfahrtiimonas chitiniclastica SH04 GN=gyrA PE=3 SV=1
-------HAQLMCFSSIGRVYWLRTYELPEAGRGSSGRPIVNMLP-ERITSILPVEAELFIVMATRHGVIKKTSLDKFASQRS--TGV---IALTLDEGD
ELIGTAIT---DGEKDIMLFTSDGKVNRFSEADVRDTRARGVKSMNLTD--QIISMIIPEADSVILIATENGYGKRTRAEEFTRHRRGGKGMIGIQTSNG
S-VISACLVKEDEEVILISSNGVLVRTRVSEISILGRNTQGVRLIRLD-ES-DQLVGLTAVE--------------------------------------
------------
>tr|Q31GD7|Q31GD7_THICR DNA gyrase subunit A OS=Thiomicrospira crunogena (strain XCL-2) GN=gyrA PE=3 SV=1
-------HDMLLCFSNRGKLYWQKTWQLPLASRGSKGKPIVNVLP-EHITSILPVSEGYYVFMATKQSTVKRVALSDFSRPRA--NGI---IAVDLLDDD
ELVGTAIT---DGEQDIMLFSNIGKAIRFDENDVRVMRARGVRGMKLKD--MIISMQVARKDTLILTATEHGYGKCTPVDDYSTINRGGQGVISIKTSNG
N-VVYSVAVTPDQEVVLITNKGTLVRTRVSEISVVGRNTQGVKLINVG-KG-EIVVGLAVVD--------------------------------------
------------
>tr|A0A066ZMU7|A0A066ZMU7_HYDMR DNA gyrase subunit A OS=Hydrogenovibrio marinus GN=gyrA PE=3 SV=1
-------HDMLLCFSNRGRLYWQKTWQLPLASRGSKGKPIVNVFP-EHITSILPVSEDKFVFMATKKSVVKRVSLTDFSRPRA--NGI---IAVDLLEGD
ELVGTALT---NGAQEIMLFSDVGKAIRFDENDVRVMRARGVRGMKLKD--VVISMQVAEPDTLILTATENGFGKCTPVEDYSTINRGGQGVISIKTSNG
N-VVSAVSVKPEQEVVLITNKGTLVRTRVSEISVVGRNTQGVKLINVG-KG-EWVVGLAVVD--------------------------------------
------------
>tr|A0A0J1JDH8|A0A0J1JDH8_PISSA DNA gyrase subunit A OS=Piscirickettsia salmonis LF-89 = ATCC VR-1361 GN=gyrA PE=3 SV=1
-------HDTLLCFSNYGKLYWLKVYTVPQASRISKGRPIVNLLPKEKIQAMLPVR-GMYIFMATAKGIVKKTALTEFSRPRV--SGI---ISVDLVEGD
RLVGVSLT---HGECDMMLFTNSGKVIRFPETDVRAMRARGVKGINLTDQR-VISSVIAPIEGDILTVTENGFGKRTKIDEYRIQGRGGQGIISIQVSNG
M-VVGAAAITHADEVMLLTNGGTLVRTRAEEISQVGRNTQGVKLINLA-NA-EKLVSVQPVV--------------------------------------
------------
>sp|Q89AS3|GYRA_BUCBP DNA gyrase subunit A OS=Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp) GN=gyrA PE=3 SV=1
-------HDIILCFSSKGILYWMKVYQLPEASRHARGRPIVNLLP-ERITAILPISDSINIFMATSKGMVKKTSLYEFKKPRT--KGI---IAINLKADD
ELIGVSLT---NGNNTIMLFTAQGKAVHFSEILVRKTRAIGVQGIKIK--KSVVSLVVPKK-GNILLITEHGYGKRTEIHEFPIKSRATQGTIAMKITNG
I-VIGTMQVVNQDQIIIITNAGTLVRTRVLEIGILGRNTQGVIIIRTS-KK-EKVVALQKAN--------------------------------------
------------
>tr|C5WC75|C5WC75_9ENTR DNA gyrase subunit A OS=Candidatus Ishikawaella capsulata Mpkobe GN=gyrA PE=3 SV=1
-------HDTILCFSSKGRLYWMKVYQLPEASRGSRGRPIVNLLP-ERITTILPVYEGLNILMATAKGIVKKTAINEFSRPRN--IGI---IAIKLHGDD
ELIGVALT---KGNDEIMLFSSAGKVVRFSETTVRNMRASGVCGIKLA--KNVVSLIVPRK-GEILTVTQNGYGKRTANSEYPTKSRATQGVISIKVTNG
L-VIGAIQVVDSDQIIIITNAGTLVRTRVSEVSIVGRNTQGVILIRTA-EN-ERVVGLQRVA--------------------------------------
------------
>tr|A0A077JER2|A0A077JER2_9CYAN DNA gyrase subunit A OS=cyanobacterium endosymbiont of Epithemia turgida isolate EtSB Lake Yunoko GN=gyrA1 PE=3 SV=1
-------HNQVLFFSDRGVVYGIPAYQIPSASRTARGIPIVQMLPKEKITSILAVSENIYLIMLTRKGYIKKTALAAFSNIRA--NGL---IAISLGEGD
QLRWVRLA---RAEDSIIIGTRQGMAIHFHA--LRPLRTRGVKAMKLK---DFISMDILSSGPWVLAITNGGYGKRVPVNKFRLQNRAGMGVKAIKFKTD
R-LASLHIVN-DNELMIVSNRGIVIRQAVNAISLQSRMATGVRVQRLDN-D-DAIAAVTLVS--------------------------------------
------------
>tr|A0A086CID9|A0A086CID9_ATETH DNA gyrase subunit A OS=Candidatus Atelocyanobacterium thalassa isolate SIO64986 GN=gyrA PE=3 SV=1
-------HDVVLFFSDRGVVYATKAYQIPSSSRTSRGIPIIQMLSKEKITSIIAVSEDIFLVMLTCQGYIKKTALAAFRNIRT--NGL---IAISLEEGD
QLRWVRLT---REEDSIILGTRLGMAIHFHA--LRPLRTRGVKSMKLK---DLISMDILLSGPWILAITNGGYGKRIPITQFRLQRRAGMGVRAIKFDKD
H-LTSLRVVN-EDELMIVSNRGIIIRQVVKAISLQSRSATGVRVQRLDE-D-DAIAAVALVP--------------------------------------
------------
>tr|T2JMV9|T2JMV9_CROWT DNA topoisomerase (ATP-hydrolyzing) (Fragment) OS=Crocosphaera watsonii WH 0402 GN=CWATWH0402_1685 PE=3 SV=1
-------HDQVLFFSDRGVVYAVNAYQIQAASRTARGIPIVQMLPKEKITSIVAVSDDVFLVMLTRNGYIKKTALSAFSNIRT--NGL---IAISLGDGD
QLRWVRLT---REEDSIILGTSNGMSIHFQA--LRPLRTRGVKAMKLK---ELISMDILTAGPWILAITNGGYGKRVPISQFRLQKRAGMGVRAIKF-SD
C-LASLRVVN-EDELMIVSNRGIIIRQAVDAISMQSRAATGVRVQRLDS-E-DAIAAVALVP--------------------------------------
------------
>tr|B7JVT1|B7JVT1_CYAP8 DNA gyrase subunit A OS=Cyanothece sp. (strain PCC 8801) GN=gyrA PE=3 SV=1
-------HDHVLFFSDRGVVYTLPAYQIPAASRTARGVPIVQMLPKEKITSIVAVSEDVYFIMLTRKGYIKKTALSAFSNIRT--NGL---IAIVLGEGD
QLRWVKVA---QEEDSIIIGTRLGMAIHFHA--IRPLRTRGVKAMKLK---ELISMDILSSGPWILTITNGGYGKRVPVKQFRLQNRAGLGVRVIKF-SD
R-LASLLVVN-EDELMIVSNRGIIIRQAVDAISTQSRMATGVRVQRLDE-D-DAIAAVALVP--------------------------------------
------------
>tr|U5Y2E7|U5Y2E7_CAMFE DNA gyrase subunit A OS=Campylobacter fetus subsp. testudinum 03-427 GN=gyrA PE=3 SV=1
-------HDTLMFVTDRGQLYWLKVYKIPEGSRTAKGKAVVNLISAEKIKAIIPTTESKSLAFFTKNGIVKRTNLSEFKNIRS--IGV---KAINLDDND
ELVTVVATSEG--GKMLFAVTKKGMCIKFA---VRQIRSRGVTAIRFKN--DVVGAVVIENSQEILSVSQKGIGKRTTADEYRLQSRGGKGVICMKLTTK
D-LVG-VVVD-EMDLMALTSSGKMIRVDMQSIRKAGRNTSGVIVVNVE-----EVVSIARCP--------------------------------------
------------
>tr|D9SF67|D9SF67_GALCS DNA gyrase subunit A OS=Gallionella capsiferriformans (strain ES-2) GN=gyrA PE=3 SV=1
-------HNFILCFSNKGRVYWMKVYDVPQGSSGARGKPIVNLLP-EKINAILPVT-DKYVFFATANGTVKKTTLTDFSRPMK--RGI---IAINLDEDD
YLIGVAIT---DGHHDVMLFSNSGKAVRFDE-DVRETRSRGVRGMKLH--ENVISMLVAENQQSVLTATENGYGKRTPVGEYTRHGRGTQGMIAIQTSNG
K-VVAATLVNPEDEIMMIGTNGVLIRTRVREIREMGRTTQGVTLMNLE-KG-ERLAGLSRIA--------------------------------------
------------
>tr|D5CTY4|D5CTY4_SIDLE DNA gyrase subunit A OS=Sideroxydans lithotrophicus (strain ES-1) GN=gyrA PE=3 SV=1
-------HDYILCFSNRGRVYWLKVYDVPQGTRISRGKPIVNLLP-EKINAILPVK-DQFIFFATSEGTVKKTPLSDFANPRK--AGI---IAISLDEGD
FLIGVAIT---DGKHDVMLFSDEGRAVRFDE-DVRGMRARGVRGMNLA--KGVIALLVAENEQSVLTATENGYGKRTPISEYTRHGRGTQGMIAIQTSNG
K-VVAATLVKPEDEIMLIGTSGVLIRTRVNEIREMGRATQGVTLMNVG-EG-EKLAGLSRIA--------------------------------------
------------
>tr|A0A0E9M8N5|A0A0E9M8N5_9PROT DNA gyrase subunit A OS=Ferriphaselus amnicola GN=gyrA PE=3 SV=1
-------HDYILCFTNRGRAYWLKVYEVPLGSRTSRGKPIVNMLA-EKINAILPVR-DKFIFFATAGGTVKKTALSQFGNPRK--AGI---IAIALDEGD
FLIGVAVT---DGKHDVMLFSDEGKAVRFDE-DVRPMRTRGVRGMNLA--KGVIALLVAEDQQGVLTATENGYGKRTPIAEYTRHGRGTQGMIAIQTSNG
K-VVAAALVNTEDEIMLIGTNGVLIRTRVREIREMSRATQGVTLINLE-AG-DKLAGLSRIA--------------------------------------
------------
>tr|M2WEN7|M2WEN7_9MICC DNA gyrase subunit A OS=Kocuria palustris PEL GN=gyrA PE=3 SV=1
-------HHWILFFTTHGRVYRTKAYELLEAGRDAKGQHVANVMAPEQIAQVMELSAP-YLVLATRSGLVKKSRLEDYDT-RT--AGV---IAINLREGD
ELVSAK-----DSDDDIFLVSRNGQSLHFQE--LRPMRTSGVTGMKFR-D-DLLAADVVAKESYVFVVTEGGYAKRTAIEQYRRQGRGGLGIKVAKVGRG
K-LAGALIVGS-DEVMVVMASGKVVRSAVSEVPA-GRDTMGVIFAKPAP-K-DSIVGVAWNA--------------------------------------
------------
>tr|Q47GP5|Q47GP5_DECAR DNA gyrase subunit A OS=Dechloromonas aromatica (strain RCB) GN=gyrA PE=3 SV=1
-------HDFILCFSNRGRCYWLKVYEAPQGSRVSRGKPIVNLFP-ERINAVLPVK-DKFIFMATRAGTVKKTPLSDFSNPRK--AGI---IAVDLLDDD
YLIGVELT---TGQSDIVLVSNAGKAVWFDE-DVRPMRARGVRGMKLQ--AGVISLLVAESQQTVLVATENGFGKRTVLADFRHSGRGTQGVKAIADSNG
V-VIGAKLVDDNDEVMLITTGGVLIRTRVSEIRGMGRATQGVTLISLD-DG-EKLAGLEKVA--------------------------------------
------------
>tr|G8QHV8|G8QHV8_DECSP DNA gyrase subunit A OS=Dechlorosoma suillum (strain ATCC BAA-33 / DSM 13638 / PS) GN=gyrA PE=3 SV=1
-------HDYILCFSNRGRCYWLKVYEVPQGSRISRGKPIINMFP-EQINAILPVK-DKYVFMCTVQGTVKKTSLANFSNPRK--AGI---IAVDLDEGD
YLIGADLT---TGQSDIVLVSDGGKAVWFGE-QVRPMRSRGVRGMMLQ--EGVISLLVAESEETVLVATENGYGKRTRLGDFRRSSRGTQGVMAIAASNG
K-IVAAKLVTDADEVMLITTGGVLIRTRVAEIRELGRATQGVTLISLD-AG-EKLSGLEKVA--------------------------------------
------------
>tr|R7LF38|R7LF38_9BACT DNA gyrase subunit A OS=Prevotella sp. CAG:891 GN=gyrA PE=3 SV=1
-------HNTMLFFTAKGRCYWLKVYELPEGAKNSKGRAIQNMLNPDSINACLHIRKTHFVLFCTKEGVIKKTCLSEYSR-RV--NGV---NAINIREED
RVVSVVLT---NGTDEIVIANRNGRAIRFN---VRPMRATGVRGIRLD-G-DVVGMICINDNETVMVVSENGYGKRSAVA-YRVTNRGGKGVKTLDITTG
P-VIAIKAVT-DNDLMIINKSGIAIRMKLSEVRVQGRATQGVRLINLEKRN-DVISSVCKVP--------------------------------------
------------
>tr|R7P8L8|R7P8L8_9BACT DNA gyrase subunit A OS=Prevotella sp. CAG:617 GN=gyrA PE=3 SV=1
-------HNTMLFFTAKGRCYWMKVYEIAEGTKNSKGRAIQNMLNRDSINACLHIKNSHYVIFCTKKGVIKKTCLSEYSR-RV--NGV---NAITIREDD
KVISVCLS---NGSDEIIIANKNGRAIRFN---VRTMRATGVRGMLLD-E-DSIGMICVHNEESVMVVSEQGFGKRSKI-DYRKTNRGGKGVKTMSITTG
K-LVAIKSVT-ENDLMIINKSGITIRLRVADVRVMGRATQGVKLINLEKRN-DSISSVCEVL--------------------------------------
------------
>tr|R5GGF5|R5GGF5_9BACT DNA gyrase subunit A OS=Prevotella sp. CAG:755 GN=gyrA PE=3 SV=1
-------HNTMLFFTAKGRCFWLKVYEIPEGTKNSKGRAIQNLLNSDAINACLHIRESHFVMFCTKNGVIKKTCLTEYSR-RT--NGV---NAITIREDD
RVVSVCLT---NGENEIILANRNGRAIRFA---VRTMRATGVRGMLLD-G-DVVGMVCVNDQETVMVVSEKGYGKRSAVE-YRMTNRGGKGVKTLSITTG
K-LVAIKIVT-DNDLMIINKSGITLRLKVADVRVMGRATQGVRLINLGKRN-DTISSVCHVS--------------------------------------
------------
>tr|C9LDN5|C9LDN5_9BACT DNA gyrase subunit A OS=Alloprevotella tannerae ATCC 51259 GN=gyrA PE=3 SV=1
-------HNTMLFFTAKGRCYWLKVYELPEGAKNAKGRAIQNMLNADSVNAFLYIKKSHYVVFCTAEGIIKKTCLEEYSR-RT--NGV---KAITIREED
RVVSVVLT---NGQDELVIANRNGRAIRFN---VRTMRSTGVRGIRLD-G-DAVGMVCINDKETIMVVSDQGFGKRSAIE-YRKTNRGGKGVKTLQLTTG
K-VAAIKSVT-DNDLMIINRSGITLRLKVADVRVMGRATQGVKLINLTKRN-DSISSVCVVT--------------------------------------
------------
>tr|R5ZZ05|R5ZZ05_9BACT DNA gyrase subunit A OS=Prevotella sp. CAG:5226 GN=gyrA PE=3 SV=1
-------HNTMLFFTAKGRCYWLKVYELPEGAKNAKGRAIQNMLNPDSINACLHIRQSHFVMFCTKQGIIKKTCLSEYSR-RA--NGV---NAINIREDD
KVVSVVLT---NGSDEIIIANRNGRAIRFN---VRAMRATGVRGMRLDAP-DVIGMICINDKETVLVVSEKGKGKRSVVE-YRVTNRGGKGVKTLNITTG
K-VVAIKAVT-EEDLMIINKSGITIRLRMDEISVQGRATQGNKLIDLKKRN-DVISSVCLVP--------------------------------------
------------
>tr|A0A0E3Y9N3|A0A0E3Y9N3_9ENTR DNA gyrase subunit A OS=Blochmannia endosymbiont of Camponotus (Colobopsis) obliquus GN=gyrA PE=3 SV=1
-------HDTILLFSNYGRIYWMKVYRLPVSNRGSRGKPIINLLP-ERITAILPVRAGYYVFMATSMGIVKKTSLIQFSRPRS--AGI---IAINLSKGD
ELIGVNLT---NGENEVMLFSSYGKVVRFFEKQVRNMRAVGVKGINLV--EGVVSLIVPLN-SSILTVTQHGYGKRTAQVEYPVRSRATQGVISIKVSNG
K-VVGAVQANDCDQIMMITDAGTLVRIPVSEVSIIGRNTQGVVLIRTV-EN-ERVVGLQRVA--------------------------------------
------------
>tr|H6Q5V6|H6Q5V6_WIGGL DNA gyrase subunit A OS=Wigglesworthia glossinidia endosymbiont of Glossina morsitans morsitans (Yale colony) GN=gyrA PE=3 SV=1
-------HDSILLFSSRGRVYWMKIFQLPETNRGSSGKPIINLLP-EYITAILPVHKEKYVFMATASGIVKKTSLSEFSRPRN--SGI---IAVNLNAGD
KLIGVDLT---DGSQEVMLFSEYGKVVRFSESQVRNMRASGVKGISLL--PGVVSLIIPKG-SPILTVTQYGYGKRTNQSEYPKKSRAIQGVISIKVSNG
K-VVGAVQVNDYDQIMIITDSGTLVRTRVSEVNIVGRNTHGVRLIRIS-KE-NNVVGLQRVV--------------------------------------
------------
>tr|C7RAM0|C7RAM0_KANKD DNA gyrase subunit A OS=Kangiella koreensis (strain DSM 16069 / KCTC 12182 / SW-125) GN=gyrA PE=3 SV=1
-------HDTILCFSSTGKVYWLKVFELPNAGRGSRGKPIVNVLP-ERINAILPIREDKFVFMATANGTVKKTSLEQFSRPRS--NGI---IALTIADDD
ELIGVVET---DGSNHIMMFSDAGKVIRFDEANVRGMRARGVRGMKLPEAK-VIQMIVAE-DGSVLTATENGYGKRTAMEDHPLRGRGGQGVISIQMSNG
A-VVSAVPVIDGDEVMLISKGGTLIRTGVDDIRIMGRNTQGVRLIKLD-DG-ETLVGLQRIV--------------------------------------
------------
>tr|A0A0F6RCW5|A0A0F6RCW5_9GAMM DNA gyrase subunit A OS=Kangiella geojedonensis GN=gyrA PE=3 SV=1
-------HDMILCFSSRGKVYWLKVFELPNAGRGSRGKPIVNVLP-EKISAILPIREDRFVFMATANGTVKKTSLEQFSRPRA--NGI---IALTIADDD
ELIGVAET---AGEDEIMLFSDAGKVIRFGEDAVRAMRARGVRGMKLPDAK-VIQMLVAE-DCSILTATENGYGKRTSVEDHPLRGRGGQGVISIQMSNG
Q-VVSAVPVIEGDEVMLISKGGTLIRTGVDDIRIMGRNTQGVRLIRLD-DN-ETLVGLQRIV--------------------------------------
------------
>tr|A0A0D0HR84|A0A0D0HR84_HAEIF DNA gyrase subunit A OS=Haemophilus influenzae GN=SU59_05115 PE=3 SV=1
-------HDTILCFSSRGRLYWLKVYQLPQASRGARGRPIVNILP-ERITAILPVSEDKFVVMATAGGIVKKITLTEFSR-RS--NGI---IALNLRDED
ELIGVDIT---DGSNEIMLFSSQGRVVRFAENAVRAMRATGVRGIKLATDNIVVSLVVPKGEGEILTATQNGYGKRTQLSEYPTKSRNTKGVISI--SNG
K-VVAATQVE-TDQIMLITDAGTLVRTRISEVSIVGRNTQGVRLIRTAD-D-EHVVSLERVC--------------------------------------
------------
>tr|A0A0G3EIK4|A0A0G3EIK4_9BACT DNA gyrase subunit A OS=Verrucomicrobia bacterium L21-Fru-AB GN=gyrA_1 PE=3 SV=1
-------HDTMLCFTETGRLYRLKTWQIPEAARQSRGRSVANLL-EESLASIHCVRDDCCLLMATRKGIVKKTPLSAYRNIRT--VGI---RAVNVEDGD
RLVGVR-V---REGDDVLLTTRRGMTIRFSE--ARPMRARGVRGISLS---DVVSLEIVDP-TDLLTVTEQGYGKRTSFDEYRRQSRGGKGLIGI--TNG
N-VVGAHAVREEDGVMLITQSGQLVCIAVNEVSRIGRNTQGVRLVRLNE-D-DRLVSAAVLL--------------------------------------
------------
>tr|A0A011P2Q6|A0A011P2Q6_9PROT DNA gyrase subunit A OS=Candidatus Accumulibacter sp. BA-93 GN=gyrA PE=3 SV=1
-------HDSILCFTNRGRVYWLKVYEVPQGTRTSRGKPVVNVFP-EKISAILPIK-DRYIFMATSQGTVKKTPLSDFSNPRK--NGI---IAVALDDED
FLIGAEVT---NGSQDVILVSDAGKAVWFDE-DVRPMRARGVRGMRLA--DRVLSLLIADSQQTVLVATENGFGKRTALADFRHSGRGTQGVIAISASNG
K-VVAARLVSDDDEIMLITTGGVLIRTRVREIRELGRATQGVTLIALD-PG-EKLAGLEKVV--------------------------------------
------------
>tr|A0A080M9D6|A0A080M9D6_9PROT DNA gyrase subunit A OS=Candidatus Accumulibacter sp. SK-02 GN=gyrA PE=3 SV=1
-------HDFILCFTNRGRVYWLKVYEVPQGTRSSRGKPIVNLFP-EKISAILPVK-DRYIFMCTANGTVKKTPLSDFSNPRK--AGI---IAVALDEDD
VLIGAEIT---NGLQDVVLVSDVGKAVWFDE-EVRPMRARGVRGMRLA--DQVLSLLVADNQQTVLVATENGFGKRTILADFRHSGRGTQGVKAIAASNG
K-VVAARLVRDEDEIMLITTGGVLIRTRVREIRELGRATQGVTLIALD-AG-EKLAGLEKVV--------------------------------------
------------
>tr|A0A0Q0QJ95|A0A0Q0QJ95_9VIBR DNA gyrase subunit A OS=Vibrio metoecus GN=XV91_00905 PE=4 SV=1
-------HDNILLFSTRGKTYRMKVYQLPLASRTARGKPIVNLLP-ERITAIL--PEDKFIFMATGDGTVKKTSLDQFAN-RA--NGL---IAVNLRDDD
ALIGVEIT---DGESDIMLFSKSGKVVRFNEKGVRPMRAAGVRGIKLV---GVVSLIVPKNDGDILTVTENGYGKRTTLDEYPAKSRATQGVVSI--SNG
S-VVGAVQVT-GDEFMMITNAGTLVRTRVAEVSQVGRNTQGVTLIRTSE-G-ESVVGLQRID--------------------------------------
------------
>tr|F2I5D3|F2I5D3_AERUA DNA gyrase subunit A OS=Aerococcus urinae (strain ACS-120-V-Col10a) GN=gyrA PE=3 SV=1
-------HDVILCFTDRGRVFQIKGYEIPEYGRAAKGLPIVNLLNQEQVRGVINVTSEDYFFFVTKQGTVKRTPVEEYFN-RN--NGL---IAINLRDDD
ELVAVL-T---SG-DNIILGSHQGYAVSFAE--VRSMRATGVRGIRLD---DVVGASILGPDQDVLIVTEKGYGKRTPADEYSIKHRGGKGVKTVNITNG
P-LVGLATVDD-EDIMLMTDEGVVIRFHSVDISQTGRATQGVRLMRLDEA--AHVSTMAVVD--------------------------------------
------------
>tr|D4YHA6|D4YHA6_9LACT DNA gyrase subunit A OS=Aerococcus viridans ATCC 11563 GN=gyrA PE=3 SV=1
-------HDSVLFFTNTGRVFHSKGYEIPEFGRAAKGIPVVNLLNQETVQAMINVTVKEHLLFVTKNGTVKRTNASDYFN-RN--NGL---IALKLAEGD
ELVKVV-T---SG-DNIIIASRDGYAVSFQE--VRSMRATGVRGIRLN---GVVGMSVLGPDDNVLVVTEKGYGKQTPASEYGIKNRGGKGVKTINVTNG
I-LVGLTTVSE-EDIMLMTNQGIAIRFHAKNISQTGRATQGVRLIRLAED--SYVSAIAKVE--------------------------------------
------------
>tr|A0A0J0YIJ4|A0A0J0YIJ4_9FLAO DNA gyrase subunit A OS=Flavobacterium sp. ABG GN=gyrA PE=3 SV=1
-------HQYMMFFTQKGKCFWMRVYEIPEGSKTAKGRAIQNLVNSDKVKAFICTQNSHNLVMVTKQGQVKKTSLEKYSK-RV--NGV---AAITIKEGD
ELLEAKLT---NGESQIILAVKSGKLVRFE---TRPMRASGVRGITLKD--DVIGMVTVDKDSQILVVTENGYGKRTKLVVYRITNRGGKGVKTLNITTG
K-LISINAVT-ADDLMIINKSGLTIRMAIEDLRVMGRATQGVRLINLKG-K-DSIAAVTKVM--------------------------------------
------------
>tr|K4IIR4|K4IIR4_PSYTT DNA gyrase subunit A OS=Psychroflexus torquis (strain ATCC 700755 / ACAM 623) GN=gyrA PE=3 SV=1
-------HQYILFFTQKGKCFWMRVFEIPEGSKTSKGRAIQNLMNPDRINAFILVENNHYVLMVTKKGQVKKTILEQYSR-RI--NGI---NAISVRDGD
ELLSAVLT---DGENQVMLGLRSGKALRFE---IRPMRAAGVKGITLAE--DVIGMICVKNEETVLVVSEKGYGKRTFIDVYRITNRGGKGVKTISISTG
Q-LVAMKTVH-EDDLMIIKKSGVAIRMSVSDIRTMGRSTQGVRLISLKG-D-DEIAAVAKII--------------------------------------
------------
>tr|A0A0A2MI37|A0A0A2MI37_9FLAO DNA gyrase subunit A OS=Flavobacterium subsaxonicum WB 4.1-42 = DSM 21790 GN=gyrA PE=3 SV=1
-------HNYMLFFTQKGKCFWMRVYEIPEGTKTSKGRAIQNLINNDKVKAFICTQNSHYVIMATKQGIVKKTLLEQYSR-RL--NGI---NAITIREDD
MLLEAKLT---TGESQVLIAVKSGKLVRFE---TRPMRASGVRGITLQD--DVIGMVSVNDNSEILVVSEKGYGKRSSL-DYRITNRGGKGVKTLNITTG
S-LVSINNVT-ADDLMIINKSGLTIRMAVSDLRVMGRATQGVRLINIKG-N-DSIAAVTKVM--------------------------------------
------------
>tr|K9UZ17|K9UZ17_9CYAN DNA gyrase subunit A OS=Calothrix sp. PCC 6303 GN=gyrA PE=3 SV=1
-------HDSVLFFSDRGVVYSLRAYQIPVSSRTSRGTPIVQMLPKEKITSVVHVDSEEYLVMLTRGGNIKKTALEAFSHIRS--NGL---IAISLEEGD
QLRWVRRA---KPEDSVLIGSRQGMAIHFRC--LRPLRTRGVKSMKLK---DLVGMDILPAGLWVLVITMGGYGKRVPVAQFRLQNRAGQGLMATKFKKD
K-LAALHIVNDD-EIMMVTSRGIIIRQAVNAISVQSRSATGVRVQRLDE-D-DALTGVAVVP--------------------------------------
------------
>tr|E6KA47|E6KA47_9BACT DNA gyrase subunit A OS=Prevotella buccae ATCC 33574 GN=gyrA PE=3 SV=1
-------HQTMLFFTKKGRCYWLKCYEIPEGDRNSKGRAIQNLLNGDQVNAFLRLRNSHYVVFATKNGTVKKTLLEAYSR-RA--NGV---IAINIVEGD
EVVDVRLT---NGNNELIIANRNGRAVRFH---IRTMRSTGVRGMRLD---DVVGMIVVNDTENVMVVSENGYGKRSQVE-YRITNRGGKGVKTLAVTTG
R-LVAIKNVT-DNDLMIINKSGVVIRLAVADCRVMGRATQGVRLINLAKKN-DVIASVCKVM--------------------------------------
------------
>tr|R7GUN8|R7GUN8_9BACT DNA gyrase subunit A OS=Prevotella stercorea CAG:629 GN=gyrA PE=3 SV=1
-------HQTMLFFTRKGRCYWLKCYEIPEGDKNFKGRAIQNMLNPDSVNALLRLRKSHYVVFATKNGTVKKTSLEAYSR-RT--NGV---NAINIVEGD
EVVDVRLT---NGKNEIILANRNGRAVRFD---IRTMRSTGVRGMKLD---DVVGMIVVNNTETVMVVSENGYGKRSQVE-YRKTNRGGKGVKTFSITTG
R-LVAIKNVT-DNDLMIINKSGIAIRLAVSECRVMGRATQGVRLINLSKKN-DVIASVCKVM--------------------------------------
------------
>tr|D5EZ76|D5EZ76_PRER2 DNA gyrase subunit A OS=Prevotella ruminicola (strain ATCC 19189 / JCM 8958 / 23) GN=gyrA PE=3 SV=1
-------HNTLLFFTQKGRCYWQKCYEIPEGDKNSKGRAIQNMLNPDAINAVLRIKNSHYVVFATKQGIIKKTCLEAYSR-RA--NGV---IAININEGD
QVVGVRLT---NGHNELLLANRNGRAVRFD---VRVMRSTGVIGMRLD---DVVGMVCVNDTETIMVVSENGYGKRSEVE-YRKTSRGAKGVKTLSITTG
R-LVAIKVVT-ENDLMIINKSGVLIRLKVADVRVMGRATQGVRLINLTKKN-DSIASVCKVM--------------------------------------
------------
>tr|L1NFU2|L1NFU2_9BACT DNA gyrase subunit A OS=Prevotella saccharolytica F0055 GN=gyrA PE=3 SV=1
-------HQTMLFFTKKGRCYWLKCYEIPEGDKTSKGRAIQNLLNADAVNAFLRVKNNHYIVFATKNGTVKKTCLQAYSR-RA--NGV---IAISIAEGD
EVVDVRLT---NGKNELIIANRNGRAVYFD---IRTMRATGVRGMRLD---DVVGMIVVNDSETVMVVSENGYGKRSLVE-YRKTKRGGKGVKTLNITTG
K-LVAIKNVT-DNDLMIINKSGIVIRLAVSDCRVMGRATQGVRLINLAKKN-DVIASVCKVM--------------------------------------
------------
>tr|D1W7U2|D1W7U2_9BACT DNA gyrase subunit A OS=Prevotella buccalis ATCC 35310 GN=gyrA PE=3 SV=1
-------HQTMLFFTKKGRCYWLKCYNIPEGAKDSKGRAIQNLLNSDAINAILRLRNSHYVVFATKNGTVKKTSLEAYSR-RT--NGV---IAINIAEGD
EVVDVRLT---NGENELIMANRNGRAVRFD---VRTMRATGVRGMRLD---DVVGMIVVNDNETVMVVSENGYGKRSLVE-YRKTNRGGKGVKTLSITTG
R-LVAIKNVT-DNDLMIINKSGITIRLAVSECRVMGRATQGVRLINLSKKN-DVIASVCKTM--------------------------------------
------------
>tr|E0NRN6|E0NRN6_9BACT DNA gyrase subunit A OS=Prevotella marshii DSM 16973 = JCM 13450 GN=gyrA PE=3 SV=1
-------HNTMLFFTRKGRCYWLKCYEIPEGTKDSKGRAIQNMLNSDSVNAFLRLKNSHYVVFATKNGVVKKTLLKAYSR-RA--NGV---NAINIVDGD
EVVNVRLT---NGSNELILANRNGRAVRFD---VRTMRSTGVRGMRLD---DVVGMVVVNEKESVMVVSENGYGKRSSVE-YRKTNRGGKGVKTLSITTG
R-LVSIKNVT-ENDLMIINKSGITIRLAVSNVRVMGRATQGVRLINLTKKN-DVIASVCKVM--------------------------------------
------------
>tr|H1HM42|H1HM42_9BACT DNA gyrase subunit A OS=Prevotella maculosa OT 289 GN=gyrA PE=3 SV=1
-------HQTMLFFTKKGRCYWLKCYEIPEGDRNSKGRAIQNMLNSDAINAILRLTNSHYVIFATKHGTVKKTSLEAYSR-RA--NGV---IAINIADED
EVVDVRLT---NGKNELIMANRNGRAVRFD---IRTMRATGVRGMRLD---DVVGMITVNDVETVMVVSEQGYGKRSQVE-YRITNRGGKGVKTLAITTG
R-LVSIKNVT-ENDLMIINKSGVVIRLAVADVRVMGRATQGVRLINLAKKN-DAIASVCKVM--------------------------------------
------------
>tr|A0A099BVU6|A0A099BVU6_9BACT DNA gyrase subunit A OS=Prevotella sp. S7 MS 2 GN=gyrA PE=3 SV=1
-------HQTMLFFTRKGRCYWLKCFEIPEGDRNSKGRAIQNMLNPDAINAILRLRNSHYVVFATKNGTVKKTSLEAYSR-RA--NGV---IAINIAEGD
EVIDVRLT---NGRNELILANRNGRAVRFN---IRTMRATGVRGMRLD-K-DVIGMIVVDDKETVMVVSEQGYGKRSDVE-YRVTNRGGKGVKTLAITTG
K-LVSIKNVT-DNDLMIINKSGIVIRLAVSDVRTMGRATQGVRLINLAKKN-DVIASVCKVM--------------------------------------
------------
>tr|U2MU69|U2MU69_9BACT DNA gyrase subunit A OS=Prevotella pleuritidis F0068 GN=gyrA PE=3 SV=1
-------HQTMLFFTKKGRCYWLKCYEIPEGDKISKGRAIQNLLNPDAVNAFLRLKNSHYVVFATKNGVVKKTCLEAYSR-RT--NGV---IAINITDND
EVIDVRLT---NGKNEIIMANRNGRAVRFD---IRTMRATGVRGMRLD---DVVGMIVVNDNETVMVVSEEGYGKRSDVE-YRKTNRGGKGVKTLSITTG
R-LVSIKNVT-DNDLMIINKSGIVIRLAVADVRVMGRATQGVRLINLAKKN-DVIASVCKVM--------------------------------------
------------
>tr|D3IG10|D3IG10_9BACT DNA gyrase subunit A OS=Prevotella sp. oral taxon 317 str. F0108 GN=gyrA PE=3 SV=1
-------HQTMLFFTKKGRCHWLKCYEIPEGDKTSKGRAIQNLLNADSVNAFLRVKKNHFIVFATKNGTVKKTSLEAYSR-RT--NGV---NAITIAEGD
EVVDVRLT---NGKNQLIMANRNGRAVYFD---VRTMRATGVRGMRLD---DVVGMIVVNNTETVMVVSETGYGKRSIVS-YRQTNRGGKGVKTLNITTG
K-LVAIKNVT-DNDLMIINKSGIAIRLAVANFRVMGRATQGVRLINLSKKN-DVIASVCKVK--------------------------------------
------------
>tr|D8DZ12|D8DZ12_PREBR DNA gyrase subunit A OS=Prevotella bryantii B14 GN=gyrA PE=3 SV=1
-------HQTMLIFTKKGRCYWLKCYEIPEGDRNSKGRAIQNMLNKDAVNGFLRLRNSHYVIFATKNGTVKKTCLEAYSR-RA--NGV---IAINLAEGD
ELVDVRLT---NGENELIIANRNGRACRFH---IRTMRATGVRGMKLD---DVVGMVPVNNVETVMVVSEQGYGKRSQVE-YRITNRGGKGVKTLAITTG
R-LVAIKNVT-ENDLMIINKSGIAIRLSVADVRVMGRATQGVRLINLSKKN-DIIASVCKVM--------------------------------------
------------
>tr|U2P9Y9|U2P9Y9_9BACT DNA gyrase subunit A OS=Prevotella baroniae F0067 GN=gyrA PE=3 SV=1
-------HQTMLFFTKKGRCYWLKCYEIPEGGKDSKGRAIQNMLNPDAINAILRLKNSHYVVFATKNGTVKKTSLEAYSR-RT--NGV---IAINITEGD
EVVDVRLT---NGDNELIIANKNGRAVRFN---VRTMRATGVRGMRLD---DVVGMVVVNNEETIMVVSENGYGKRSQVE-YRVTNRGGKGVKTLNVTTG
L-LVAIKNVT-ENDLMIINKSGIVIRLAVADCRVMGRATQGVKLINLEKKN-DVIASVCKVM--------------------------------------
------------
>tr|A0A0M2GWY7|A0A0M2GWY7_9MICO DNA gyrase subunit A OS=Microbacterium ketosireducens GN=gyrA_2 PE=3 SV=1
-------HHWLLFFTTKGRVYRSKAYELPEAGRDAKGQHAANFLAPEEIAQILDIRAT-YLVLATRGGLVKKTRLTDYDT-RQ--GGV---IAIRLRESD
EVVSAM-----DEGDDILLISRHGMSLRFTD--LRPMRTEGVKGMSFR-R-DLLSASVVRDEGYVFVVTEGGYAKRTSVDQYRVQSRGGLGIKVAKLHRG
D-LAGGLIVSI-DEVLVVLASGKVVRSAVAEVPA-GRDTMGVVFARAAD-D-DRILAIARNG--------------------------------------
------------
>tr|A0A0Q8B0R9|A0A0Q8B0R9_9MICO DNA gyrase subunit A OS=Microbacterium sp. Root166 GN=ASD56_04765 PE=4 SV=1
-------HHWLLFFTTKGRVYRSKAYEVPEAGRDAKGQHVANLLAPEEIAQILDIRAE-HLVLATRSGLVKKTRLTEYDT-RQ--GGV---IAIKLREGD
EVVSAL-----ESGDDILLISRHGMSLRFTE--LRPMRTEGVKGMSFR-D-DVLSASVVKDDGSVFVVTEGGYAKRTAVDQYRTQSRGGLGIKVARLTRG
V-LAGGLIVAD-DEVLVVLASGKVVRSAVAEVPA-GRDTMGVVFARAAD-E-DRIIAIARNG--------------------------------------
------------
>tr|A0A074UK08|A0A074UK08_9MICO DNA gyrase subunit A OS=Microbacterium sp. SUBG005 GN=gyrA PE=3 SV=1
-------HHWLLFFTNKGRVYRSKAYEVPEAGRDAKGQHVANLLAPEEIAQILDIRAT-YLVLATRGGLVKKTRLDEYDT-RQ--GGV---IAIKLRGAD
ELVSAL-----DEGDDILLISRLGMSLRFSS--LRPMRTSGVKGMDFR-G-DLLSASVAKDDEFVFVVTEGGYAKRTAVTEYRMQNRGGLGIKVARLTRG
V-LAGGMMVSS-DEVLVVLASGKVVRSSVAEVPA-GRDTMGVVFARAGG-D-DRIIAIARNA--------------------------------------
------------
>tr|A0A0B3A943|A0A0B3A943_9ARCH DNA gyrase subunit A OS=archaeon GW2011_AR4 GN=gyrA PE=3 SV=1
-------HDTMLFFTNKGMVHWLKVYDIPETARHAKGKPVVNLISEENISAIVPVDDYHFILMGTEQGIVKKTNLIEYSRPRK--GGI---IGITLREGD
SLIEVK-T---DGKQQVILATTSGMANRFNE--VRPMRASGVIGIRLK---DVVGMVLGEDDHYLLTITEQGYGKRTTMSEYRLTARGSSGVRNI--SNG
V-VVGVLSVVDNDQVLFISKNGVVIRTSAAAIRPIGRNTQGVRLMKLEE-E-DSVASAARIP--------------------------------------
------------
>tr|R0FXB3|R0FXB3_9BURK DNA gyrase subunit A OS=Herbaspirillum frisingense GSF30 GN=gyrA PE=3 SV=1
-------HDYILCFSNRGRLYWLKVWEVPQGSRNSRGKPIVNMFP-EKITVILPVS-DRYVFMATSLGTVKKTPLSDFSNPRK--AGI---IAVDLDEGD
FLIGAALT---DGAHDVMLFSDAGKAVRFDENDVRPMRARGVRGMNLE--ETVIALLVAEN-QSVLTATENGFGKRTPITEYTRHGRGTKGMIAIQTSNG
K-VVAATLVDSTDEIMLITTGGVLIRTRVSEIREMGRATQGVTLIAVE-DG-TKLSGLQRVV--------------------------------------
------------
>tr|C3XD38|C3XD38_OXAFO DNA gyrase subunit A OS=Oxalobacter formigenes OXCC13 GN=gyrA PE=3 SV=1
-------HDYILCFSDRGRMYWLKVWEVPQGSRNSRGKPIVNMFP-EKITVILPLS-NHYIFMATSQGTVKKTSLTDFSNPRK--AGI---IAVGLDEGD
YLIGAALT---DGKHDVMLFSDAGKAVRFDENDVRPMRARGVRGMNLE--DDVIAMLVAGD-QSVLTATENGFGKRTPIAEYTRHGRGTKGMIAIQTSNG
K-VVAATLVNENDEIMLITTGGVLIRTRVSEVREMGRATQGVTLIAVE-EG-TTLSGLQRIL--------------------------------------
------------
>tr|A9BB46|A9BB46_PROM4 DNA gyrase subunit A OS=Prochlorococcus marinus (strain MIT 9211) GN=gyrA PE=3 SV=1
-------HDNLLLFSDRGVAYSLPAYRVPISSRSAKGTPVVQLLPREAITSLLSVSDDNHLLMLTKGGYIKRTLVSAFSKIRA--NGL---IAISLEDGD
ALTWVRLA---ASGDSVLIGSRKGMTIHFRL--LRPLRARGVRSMNLR---DLVGMDVLPRGPWVLVASASGLGKRVPVTQFRLQKRAGMGLRAIKF-GD
S-LVGLKVLG-GEELLFVTEKGIIVRTSADKISQQSRAATGVRLQRLDS-G-DHLSEVVLVP--------------------------------------
------------
>tr|A0A0A2BN07|A0A0A2BN07_9PROC DNA gyrase subunit A OS=Prochlorococcus sp. MIT 0602 GN=gyrA PE=3 SV=1
-------HDNLLLFSAKGVAYSVPAYRVPQCSRAAKGTPVVQLLPREAITSLISVSEDNHLLMLTTGGFIKRTPVSAFSKIRA--NGL---ISINLEEGD
SLRWVKLA---SSGDSVLIGSRTGMTIHFRL--LRPLRARGVRSMNLR---DLVSMDVLSKGPWVLVASANGLGKRVPVTQFRLQKRAGMGLRAIKF-RD
K-LVGLKVLD-GEELLLVSEKGVIVRTSADKVSQQSRAATGVRLQRLDT-G-DHLAEVVLVP--------------------------------------
------------
>tr|Q7VBF8|Q7VBF8_PROMA DNA gyrase subunit A OS=Prochlorococcus marinus (strain SARG / CCMP1375 / SS120) GN=gyrA PE=3 SV=1
-------HDNLLLFSVRGVSYSVPAYRVPQCSRAAKGTPVVQLLPRESITSLISVSDDNYLLMLTIGGFIKRTPVSAFSKIRA--NGL---ISINLEDGD
ALRWVRLA---SSADSVLIGSKAGMTIHFRL--LRPLRARGVRSMNLR---DLVSMDVLSKGPWILVASADGLGKRVPVTQFRLQKRSGMGLRAMKF-TD
E-LVGLKVLD-GEEVLLVSEKGVIVRTSADKISQQSRAATGVRLQRLDS-G-DHLSEIVLVP--------------------------------------
------------
>tr|R4YWH2|R4YWH2_9ACTN DNA gyrase subunit A OS=Candidatus Microthrix parvicella RN1 GN=gyrA PE=3 SV=1
-------HAYLLFFTNRGKVYRLKVHRIPMMDRGAQGTAIVNLLRSERVEAVID--SHRYLMFTTSHGVVKKTRFTAYDSSRQ--DGL---IAVSLRDGD
ELVEVL-V---NDDDEVMLVSSSGMGIRFAE--VRPMRAAGVRGMRLK---DVIGSAVITPDTRLLTVTDGGYGKRTDPDEFTRQGRGGQGVRAH--RRG
R-VVAANLVAEDSEIFLITDAGVIIRTPVGSISEYGRDAMGVTVMRLDG-D-TKVVAVAPVV--------------------------------------
------------
>tr|R7F500|R7F500_9BACT DNA gyrase subunit A OS=Prevotella sp. CAG:485 GN=gyrA PE=3 SV=1
-------HNHILFFTRKGRCYWLKVYEIPEGAKNSKGRAIQNLLNGDQVNAFIRVKTSHNLIFCTRQGIIKKTSLEAYSR-RT--NGV---NAIIIREGD
QVIQVRLT---DGNADIMLANRKGRAVRFH---VREMRSTGVRGMTLDE--DVIGMITLRGEETVMVVSENGFGKRSIPAEYRITNRGGKGVVTMNVTTG
M-VVAIKNVT-ANDLMIINQSGVTLRLPVDTIRVTGRATQGVKLIDLRKRG-DVIASVCKVE--------------------------------------
------------
>tr|R7J0R4|R7J0R4_9BACT DNA gyrase subunit A OS=Prevotella sp. CAG:873 GN=gyrA PE=3 SV=1
-------HATMLFFTSRGLVYKMRVFELPEGAKNSKGRALQNLLNPDKVNVFIACKNSHNLVFATERGVVKKTSLAEYARVLA--KGK---KAIVLRDGD
HLVSVQLT---DGNSQILLANSGGRAIRFDE-KIRQMRSTGVRGMTLDD--RVVGMISISPSNTILALSEKGMGKRTPLEPYRVTGRGGKGVLTM--STG
E-LVAFLSVNDDEDLVIINRSGIALRIRIADVPVLSRSTMGVRIINLNR-R-DDEIASACAV--------------------------------------
------------
>tr|R5APD5|R5APD5_9BACT DNA gyrase subunit A OS=Prevotella sp. CAG:1031 GN=gyrA PE=3 SV=1
-------HSTLLFFTNSGRCYWLKVYELPEGAKNSKGRAIQNLLNADKISAVIPVKSTHNLVFATKNGVIKKTRLEAYSR-RR--DGV---NGIIIRPDD
QLINVALT---DGNSQILLANRNGRAIRFD---VREMRSTGVRGMTIDG--DVVGMICMEPQNTVLVISENGYGKRSLLDAYRITNRGAKGVKTINVTVG
K-LVGILSVN-DNDIMIINKSGITLRINASAIRVMGRAAQGVRLINLGRRN-DSIASVCCVA--------------------------------------
------------
>tr|G8TFI5|G8TFI5_NIAKG DNA gyrase subunit A OS=Niastella koreensis (strain DSM 17620 / KACC 11465 / GR20-10) GN=gyrA PE=3 SV=1
-------HHTMLFFTEKGRCYWLNVYEIPEGDKTSKGRAIQNLIQPDKIRAIIDIQKSHNIVLATKKGIIKKTALEDFSR-RT--TGV---NAITIVEGD
ELLVAKLT---NGNSEIMMAVKSGRAIRFA---VRATRAIGVSGIDVDD--DVIGMICVSKSRSVLVVSEKGYGKRTALE-YPITNRGGKGVKTLNVTTG
S-LVGMLDVA-KEDLMITCKSGMTIRMPADGISELGRNTQGVKLIRLDD-G-DEIAAITKLD--------------------------------------
------------
>tr|A0A0C1LEG1|A0A0C1LEG1_9SPHI DNA gyrase subunit A OS=Flavihumibacter solisilvae GN=gyrA PE=3 SV=1
-------HHTMLFFTEKGRCYWLKVYEIPEGEKNSKGRAIQNLMQPDKVRAIIDVSQQHYILLCTKQGVIKKTLLEDFSR-RQ--TGV---NAITIIEGD
QLLDARMT---DGSCEIMMAVKSGRAIRFP---VRPTRAIGVGGIEVDK--DVIGMICVKKEKTVLVVSEKGFGKRTPID-YRITNRGGKGVKTISVTTG
P-LVGILDVK-SEDLMITCKSGLTIRTGIADIREAGRATQGVKLISLQG-G-DEIAAITKLD--------------------------------------
------------
>tr|C7PUW6|C7PUW6_CHIPD DNA gyrase subunit A OS=Chitinophaga pinensis (strain ATCC 43595 / DSM 2588 / NCIB 11800 / UQM 2034) GN=gyrA PE=3 SV=1
-------HHTMLFFTEKGRCYWLKVYEIPEGEKSGKGRAIQNLINTDKIRAIIDIKSSHYIVLCTANGIIKKTLLEDFSR-RQ--NGV---NAITINEGD
QLLEAKLT---NGNSQIMMAIKSGRAIRFP---VRDTRAIGVRGIEVDD--DVVGMICVNKTRTVLVVSEKGFGKRTDIEEYRITNRGGKGVKTINITTG
S-LIAILDVT-KDDLMITCKSGITIRMAVADIREAGRATQGVRLIRLDD-S-DEIAAVARLD--------------------------------------
------------
>tr|A0A0E9N7F0|A0A0E9N7F0_9SPHI DNA gyrase subunit A OS=Flavihumibacter petaseus NBRC 106054 GN=gyrA PE=3 SV=1
-------HHTLLFFTEKGRCYWLKVHEIPEGEKNSKGRAIQNLMQSDKVRAVIDIPEKHYIILCTKQGIIKKTELADFSR-RQ--TGV---NAITIVEGD
QLLDARLT---DGDCEIMMAVKSGRAIRFP---VRPTRAIGVTAIEVDT--DVIGMICVKTDKTVLVVSEKGFGKRTPID-YRVTNRGGKGVKTINITTG
P-LVGILDVT-KQDLMISCKSGLTIRTAISDIREAGRATQGVKLINLQE-K-DAIASLTTIR--------------------------------------
------------
>tr|W0EZE1|W0EZE1_9SPHI DNA gyrase subunit A OS=Niabella soli DSM 19437 GN=gyrA PE=3 SV=1
-------HHTLLFFTEKGRCYWLNAYQIPEGEKTGKGRAIQNLMQPDKIRAIIDVQASHNIVLCTKKGIIKKTALADFSR-RQ--TGV---NAITINEGD
QLLEAKMT---DGKSEIMMAVKSGRAIRFS---VRPTRAIGVGGIEVDE--DVIGLICLAADKSVLVVSEKGYGKRTKVE-YRFTNRGGKGVKTINVTTG
S-LVGLLDVD-TQDLLITCKSGITIRMPISGISELGRATQGVKLIRIEE-D-DQIAAISKVD--------------------------------------
------------
>tr|M1LUD7|M1LUD7_9PROT DNA gyrase subunit A OS=Candidatus Kinetoplastibacterium crithidii TCC036E GN=gyrA PE=3 SV=1
-------HEYLLFFSDLGRVYWIKVWETPQGSRGSKGKPVINLFP-EKITVILPVK-DLYVFMATAKGTVKKTPLSDFSNPRK--NGI---IAVGLNDGD
YLIGAELT---NGDYDVMLFSDSGKAVRFNEKDVRSMRARGVRGMILG--KNVVSLLVSNN-KSVLIATENGFGKRTSIKQYTVHNRSTKGMIAIQNSNG
K-VIGAVLVNPNDEIMLITTAGVLVRTRIAEIRNMGRITQGVTLINIA-KG-SYLSKVRKVV--------------------------------------
------------
>tr|A0A081G3T0|A0A081G3T0_9ALTE DNA gyrase subunit A OS=Marinobacterium sp. AK27 GN=gyrA PE=3 SV=1
-------HDTILCFTNHGKVYWRKVYEIPPASRTSRGRPVVNILP-ERISAILPVKSERFIFLATANGTVKKTPLEAFSRPRS--TGL---IALEIVEGD
RLIGASIT---NGNDDVMLVTSAGKAIRFNENDVRAMRARGVRGVRMEEAS-VISLIIPR-GARVLTASANGYGKQTAVEDFPLRGRGGQGVIAMQCTNG
D-LAGAVQVLDGDDVMLISDRGTLVRTRSEEISTLGRNTQGVMLIRLA-EG-EKLSGLARIE--------------------------------------
------------
>tr|E1QGC8|E1QGC8_DESB2 DNA gyrase subunit A OS=Desulfarculus baarsii (strain ATCC 33931 / DSM 2075 / VKM B-1802 / 2st14) GN=gyrA PE=3 SV=1
-------HSYLLIFTDAGRLYWLKVHEIPQAGRASRGKAIVNLVQPESVSTVLAVR-GRQVIMATQKGVIKKTELMSFSR-RA--GGI---IAINLAEGD
HLVSAR-T---DG-MEVFLATRQGQAIRFHE--VRSMRAAGVKGIDVE--DQVVAMEAVAGAPTMLTITENGFGKRTRMDEYPARNRAGKGVITIKTTNG
H-VVSALVVGD-DEVMLITDVGKVIRMKVGGISVIGRNTQGVKLIDLEP-G-ERLVAVARLA--------------------------------------
------------
>tr|A0A063Y5A2|A0A063Y5A2_9GAMM DNA gyrase subunit A OS=Nitrincola lacisaponensis GN=gyrA PE=3 SV=1
-------HDTVLCFTSRGKVYWLKVYEIPPASRASRGRPLVNILP-ERVNTILPVKEDRFIFMATAQGTVKKTPLQSFSRPRS--TGL---IALDIVEGD
CLVGAAIT---NGNDDVMLVTSAGKAVRFNEQDVRPMRARGVRGVRMPEAS-VISLIIPQ-DGKILTASEKGYGKQTAVEDFPLRGRGGQGVIAMQCTNG
A-LAGAVQVFNGDGVMLISNRGTLVRTRTDEISVLGRNTQGVMLIRLS-ED-EKLVGLARIE--------------------------------------
------------
>tr|Q2BK80|Q2BK80_NEPCE DNA gyrase subunit A OS=Neptuniibacter caesariensis GN=gyrA PE=3 SV=1
-------HDTILCFTDRGKVYWLRVFEIPVASRTARGRPIVNILP-ERISTILPVGEDKFIFMATASGTVKKTALTNFSRPRA--SGL---IALDLLDDD
HLIGAAIT---NGEDDVMLMTSAGKSMRFREEDVRPMRARGVRGVKMDDVK-VISLIIPQ-GGKILTASENGYGKKTAVDDFPVKGRGGQGVIAQQCSNG
S-LAGAVQVFDGDDVMLISDQGTLVRTGGDEISELGRNTQGVTLIRVA-DD-ERLVSVARIE--------------------------------------
------------
>tr|W9V6B4|W9V6B4_9GAMM DNA gyrase subunit A OS=Nitrincola sp. AK23 GN=gyrA PE=3 SV=1
-------HDTVLCFTNKGKVYWLKVYEIPPASRASRGRPMINILP-ECITTLLPVKENRYIFMATAMGTVKKTPLQSFARPRS--TGL---IALDTVDGD
RLIGASIT---NGNDDVMLVTSAGKAVRFNEQDVRPMRARGVRGVKMNETR-VISLIIPQ-GGNVLTASEKGYGKQTAVEDFPLRGRGGQGVIAMQCTNG
A-LAGAVQVFAGDGMMLISDKGTLVRTRTDEISVLGRNTQGVMLIRLS-DE-EKLVGIARIE--------------------------------------
------------
>tr|A3J5N9|A3J5N9_9FLAO DNA gyrase subunit A OS=Flavobacteria bacterium BAL38 GN=gyrA PE=3 SV=1
-------HQYLMYFTQKGKCYWMRVYEIPEGTKASKGRAIQNLINSDKVKAFICTQKSHNLIMVTKQGQVKKTSLEKYSK-RV--NGV---AAITIKEGD
ELLGAKLT---NGSSQVLIAGKSGKMVRFE---TRPMRASGVRGITLAE--DVIGIVTVNKETQILVVTENGYGKRTKLVVYRITNRGGKGVKTLNITTG
A-LIAINNVT-DDDLMIINKSGLTIRMMVSDLRVMGRATQGVKLINIKG-N-DSIAAVTKVL--------------------------------------
------------
>tr|D7DHN5|D7DHN5_METV0 DNA gyrase subunit A OS=Methylotenera versatilis (strain 301) GN=gyrA PE=3 SV=1
-------HDYILCFSSRGQVYWLKVYEVPQGSRTGRGKPIVNLFP-EKINAILSVK-NHFIFMATSLGTVKKTPLSDFANPRK--SGI---IAINLDEGD
FLIGAEIT---NGANDVILVSNGGKAVWFTE-DVRSMRTRGVRGMKLA--DNVLSLLIADNQQSVLVATENGYGKRTVLADFRHSGRGTQGVKAIAISNG
L-VVAAKLVNEDDEIMLITTGGVLIRTRVKEIRELGRATQGVTLINLG-EG-EKLSGLEKIV--------------------------------------
------------
>tr|O86092|O86092_METSS DNA gyrase subunit A OS=Methylovorus sp. (strain SS1 / DSM 11726) GN=gyrA PE=3 SV=1
-------HDYILCFSSRGRVYWLKYTKCRKAAA-SAVQAYRQPLP-REDQCHLPVK-NHFIFMATAQGTVKKTALVEFSNPRR--AGI---IAINLDEGD
YLIGAEVT---NGANDIVLVSNGGKAVWFDE-DVRAMRTRGVRGMKLM--PKVISLLIAEDKQTVLVATENGYGKRTVLSDFRHSGRGTQGVKAIATSNG
S-VVGARLVNDEDEIMLITTGGVLIRTRVKEIRELGRATQGVTLINLG-EN-EKLSGLEKVV--------------------------------------
------------
>tr|C6XE05|C6XE05_METGS DNA gyrase subunit A OS=Methylovorus glucosetrophus (strain SIP3-4) GN=gyrA PE=3 SV=1
-------HDYILCFSSRGRVYWLKVYEVPQGSRISRGKPIVNLFP-EKINAILPVK-NHFIFMATAQGTVKKTALVEFSNPRR--AGI---IAINLDDGD
YLIGAEVT---NGANDIVLVSNGGKAVWFDE-DVRAMRTRGVRGMKLM--AKVISLLIAEDKQTVLVATENGYGKRTVLSDFRHSGRGTQGVKAIATSNG
S-VVAARLVSDEDEIMLITTGGVLIRTRVKEIRELGRATQGVTLINLG-EN-EKLSGLEKVV--------------------------------------
------------
>tr|A0A0D6EVS3|A0A0D6EVS3_9PROT DNA gyrase subunit A OS=Candidatus Methylopumilus planktonicus GN=gyrA PE=3 SV=1
-------HDNILCFSSRGQVYWLKVYEVPQGSRTSRGKPIVNLFP-EKINAILPIK-KHYIFMATALGTVKKTPLTDFSNPRK--SGI---IAINLDDND
FLIGAEIT---DGSNDIVLVSNGGKAVWFDE-DVRSMRTRGVRGMKLQ--EDVLSLLIASDQQSMLVATENGYGKRTVLSDFRHSGRATQGVKAIQVSNG
L-VVAAKLVNDEDEIMLITTGGVLIRTRVSEIRELGRATQGVTLINLG-EN-EKLSGLEKIV--------------------------------------
------------
>tr|T1BQQ5|T1BQQ5_9ZZZZ DNA gyrase subunit A OS=mine drainage metagenome GN=B1A_06053 PE=3 SV=1
-------HDHILCFSTRGRVYWLRVYQVPVGNRTSRGKPIVNLLP-EKITAVLPVK-EHYVFMATSFGTVKKTSLSDFSRPRT--AGI---IALDLDAED
YLVGVAIT---DGQHDVMLFSDEGKAIRFAE-DVRPMRAHGVRGMRLP--EGIIALLVAENRQSVLTATENGFGKRTSVLEYTRHGRGGQGIIAIQTSNG
K-VVSAALVDPEEELMLITTGGVLIRTRVQEIREMGRATQGVTLIALD-EG-EKLVCLTRAD--------------------------------------
------------
>tr|A0A0B7IXG0|A0A0B7IXG0_9PROT DNA gyrase subunit A OS=Candidatus Methylopumilus turicensis GN=gyrA PE=3 SV=1
-------HDYILCFSSLGQVYWLKVYEVPQGSRTSRGKPIVNLFP-EKINAILPVK-NRFVFMATAMGTVKKTALNEFSNPRK--SGI---IAINLDDGD
YLIGAEIT---NGTQDIVLVSNGGKAVWFDE-DVRAMRTRGVRGMKIT--KDVLSLLVAENQQTVLVATENGFGKRTVLADFRHSGRGTQGVKAIAISNG
L-VVAARLVNDDDEIMLITTGGVLIRTRVKEIRELGRATQGVTLINLG-DG-EKLSGLEKVV--------------------------------------
------------
>tr|A0A0R2T199|A0A0R2T199_9PROT DNA gyrase subunit A OS=Methylophilales bacterium BACL14 MAG-120910-bin43 GN=ABS06_04220 PE=4 SV=1
-------HDNILCFSSRGQVYWLKVYEVPQGSRVSRGKPIVNLFP-EKINAILAVK-DEFIFMATAKGTVKKTPLSDFSNPRK--SGI---IAIKLANGD
YLVGAGVT---NGEQDIILISSGGKAVWFDE-DVRSMRAAGVRGMKLP--ATVLSLLIASSQESVLVATENGYGKRTVLSEFRKSGRGTQGVKAIQVSNG
I-VVAAKLVGDHDEIMLITTGGVLIRTRVSEIRELGRATQGVTLINLS-DG-EKLSGIEKIV--------------------------------------
------------
>tr|A0A0H4IWI1|A0A0H4IWI1_9PROT DNA gyrase subunit A OS=Methylophilales bacterium MBRSH7 GN=gyrA PE=3 SV=1
-------HDNILCFSSRGQVYWLKVYEVPQGSRVSRGKPIVNLFP-EKINAILTVK-NEYIFMATAKGTVKKTPLSDFSNPRK--SGI---IAIKLDNGD
YLIGAGIT---KGENDIVLVSNHGKAVWFGE-DVRSMRARGVRGMKLT--DGVLSLLIAENAQSVMVATENGYGKRTQLSEFRRSGRGTQGVKAIQVSNG
Q-VVGAKLVDDHDELMLITTGGVLIRTRVSEIRELGRATQGVTLINLG-DD-EKLRGLEKVA--------------------------------------
------------
>tr|A0A0Q6APF6|A0A0Q6APF6_9PROT DNA gyrase subunit A OS=Methylophilus sp. Leaf414 GN=ASG24_12070 PE=4 SV=1
-------HDYILCFSSRGRVYWLKVYEVPQGSRVSRGKPIVNLFP-EKINAILPVK-NHYVFMATAMGTVKKTALTEFSNPRK--SGI---IAINLDDND
YLIGAEVT---NGKNDIVLVSNGGKAVWFTE-DVRPMRTRGVRGMKLA--AKVLSLLIAENQQSVLVATENGYGKRTVLSEFRHSGRGTQGVKAIAISNG
L-AVAARLVTADDEIMLITTGGVLIRTRVKEIRDMGRAAQGVTLINLG-EG-EKLSGLEKIV--------------------------------------
------------
>tr|C6WVE9|C6WVE9_METML DNA gyrase subunit A OS=Methylotenera mobilis (strain JLW8 / ATCC BAA-1282 / DSM 17540) GN=gyrA PE=3 SV=1
-------HDYILCFSNRGRVYWLKVYEVPQGSRTSRGKPIVNLFP-EKINAILSVK-NHFIFMATSLGTVKKTALTEFANPRR--SGI---IAINLDEGD
YLIGAEIT---NGSNDVVLVSNGGKAVWFDE-EVRQMRTRGVRGMKLA--EDVLSLLIASNQQTVMVATENGYGKRTVLADFRRSGRGTQGVKAIAVSNG
L-VVAAKLVSDEDEIMLITTGGVLIRTRVSEIRELGRATQGVTLINLG-EG-EKLSGIEKIV--------------------------------------
------------
>tr|A0A0C1E9M7|A0A0C1E9M7_9CHLA DNA gyrase subunit A OS=Parachlamydia acanthamoebae GN=gyrA PE=3 SV=1
-------HDYLLIFTNLGRCYWLKVWQIPETGRKSKGKPLINLLEPEKIATVLRVS-A-YILMATKKGIVKKTELSEFSHPRR--KGI---WALDIVEGD
EVVTARLV---SDSQQIMLFTYHGMAVRFDQ--VRPMRARGVKGVTLKD--YVVGCEAVNGTETILIVCENGFGKRSNVEDFRQTNRGGVGVRSI--SNG
N-VVGALCVTDEDGMVMMSAQGQTVRITMKDLRVMGRNTQGVKLANLKE-G-DYLVAIQKLE--------------------------------------
------------
>tr|G1FGT8|G1FGT8_9CHLA DNA gyrase subunit A OS=Estrella lausannensis GN=gyrA PE=3 SV=1
-------HDYLLIFTTHGRCLWLKVWQIPEGSRTAKGKPLINLLAEERIATILKTR-A-DIIMATEKGVVKRSELSHFSNPRK--RGI---IALAIDEGD
ALVAARLI---GKSEKAMLFTYHGMAVRFDE--VRPMRARGVKGATLKE--RVIALEVVKGSESILVVCENGFGKRSQVEDFRETNRGSSGVRSI--SNG
N-VIAALRVDDNDSIVLMSASGQTVRISMKDVRVMGRNTQGVKLANVKE-G-DSLVSVQKLQ--------------------------------------
------------
>tr|A0A078L4U7|A0A078L4U7_9CHLA DNA gyrase subunit A OS=Chlamydia sp. 'Rubis' GN=gyrA_2 PE=3 SV=1
-------HDYLLIFTNLGRCYWLKVWQIPETGRKSKGKALINLLEPEKIATILKVS-S-CILMATKKAVVKKTLLSEFSNPRR--KGI---WALDVDEGD
EVMATRLV---HEGQQVMLFTHQGMAVRFDE--VRPMRARGVKGATLKD--YIVGCEVVNGNETVLVVCENGFGKRSLVEDFRQTNRGGVGVKSI--SNG
N-VVGALCVTDEDGMLMMSSTGQTVRINMNDLRVMGRNTQGVKLANLRE-G-DYLVAVQKIE--------------------------------------
------------
>tr|Q6MCA1|Q6MCA1_PARUW DNA gyrase subunit A OS=Protochlamydia amoebophila (strain UWE25) GN=gyrA PE=3 SV=1
-------HDYLLIFTNLGRCYWLKVWQIPETGRKSKGKPLINLLEPEKIATIQRVS-A-CILMATKRAVVKKSLLNEFSNPRR--KGI---WALDIDEGD
ELVAARLV---KPEQQVMLFTHQGMAVRFEE--VRPMRARGVKGATLRE--YIVGCEVVNGDESILVVCENGFGKRSQVDDFRQTNRGGVGVRSI--SNG
K-VIGALCVTDEDGMVMMSATGQTVRINMNDLRVMGRNTQGVKLANLKE-N-DYLVAIQKLQ--------------------------------------
------------
>tr|S4TLL1|S4TLL1_9CHLA DNA gyrase subunit A OS=Neochlamydia hartmannellae GN=gyrA PE=3 SV=1
-------HDYLLIFTSLGRCYWLKVWQIPESSRKSKGKPLINLLEPEKIATIQRVS-S-CILMTTRKGVVKKSALNNFSNPRR--KGI---WALDLDEGD
EVVAARLV---NTGQQVMIFTYQGMAVRFAE--VRPMRARGVKGVTLKE--YVVGCEVVNGDETILVVCENGFGKRSLVEDFRQTNRGGVGVRSI--SNG
N-VVGALCVADTDGMVMMTSSGQTIRISMRDLRVLGRNTQGVKLANLRE-G-DFLVAIQKVS--------------------------------------
------------
>tr|A0A0C1H918|A0A0C1H918_9CHLA DNA gyrase subunit A OS=Neochlamydia sp. EPS4 GN=gyrA PE=3 SV=1
-------HDYLLIFTNLGRCYWIKVWQIPESSRKSKGKPLVNLLEPEKIATIMRVS-A-CILMATRKGVVKKSELSHFSNPRR--KGI---WALDVDEGD
EVVAARLV---KEEYQVMIFTHRGMAVRFAE--VRPMRARGVKGVSLRE--YVVSCEVVKGDETILVVCENGFGKRSLVEDFRQTNRGGVGVRSI--SNG
N-VVGALCVADTDGMVMMTASGQAIRISMRELRVLGRNTQGVRLANLRD-N-DYLVAIQKVK--------------------------------------
------------
>tr|G1FGT2|G1FGT2_9CHLA DNA gyrase subunit A OS=Criblamydia sequanensis GN=gyrA PE=3 SV=1
-------HKDLLIFTTLGRCYWLKVWQIPEASRKAKGKPLINLLEEEKIATVLSTQ-A-CIIMATEKGVVKKTGLDQFSNPRR--KGI---YALSIDEGD
RLIAARLV---KKDQQVMLFTHHGMAVRFDE--VRPMRARGVRGATLKA--RIVGVEVVNGNETVLVVSENGFGKRSNVEDFRQTNRGGSGVRSI--SNG
N-VVAALCVEDTDGIVMMSSLGQTIRISMQNVRVMGRNTQGVKLVNLKD-D--TLVTVQKVA--------------------------------------
------------
>tr|B0B0K4|B0B0K4_STAIN DNA gyrase subunit A OS=Staphylococcus intermedius GN=gyrA PE=3 SV=1
-------HDHVLFFTNKGRVYKLKGYEVPELSRQSKGIPIVNAIEQEVISTMIAVKEEDFLVFVTKKGLIKRSALSNFNR-NR--NGK---IAIKFRDDD
ELIAVR-T---DG-KHILIGTAQASLIRFKE--VRAMRAAGVKGIRLR---GVIGLDVADDKDEILVVTEKGYGKRTSIEDYRLSNRGGMGVKTAKLTNG
R-LVCITTVED-EDLMVVTNQGVIIRMEVSNISVNGRMAQGVRLIRLDDE--QYVSTVAKVK--------------------------------------
------------
>tr|A0A0C2DIB7|A0A0C2DIB7_9STAP DNA gyrase subunit A OS=Salinicoccus roseus GN=gyrA PE=3 SV=1
-------HDYIMFFTNKGRVYRLKGYEIPELSRQSKGIPIVNMLEKEVISTMIGVKEDKFLVFATKNGLVKRSTLDNFER-NK--NGK---IAISFRGDD
ELLAVR-T---DG-KEVILGTRNANLIRFPE--IRTMRAAGVKGIKLR---DVIGLDVLSE-QSILVVTENGYGKCTPEAEYRITRRGGMGVKTANLTIG
K-LVYIAAIDD-EDLMIVTNHGVIIRLVMEEVSTTGRNTQGVRLIKMTED--QQVATVAKVK--------------------------------------
------------
>tr|A0A0D6XSL9|A0A0D6XSL9_9STAP DNA gyrase subunit A OS=Staphylococcus microti GN=gyrA PE=3 SV=1
-------HDDVLFFTNKGRVYKLRGYEVPELSRQSKGIPVVNAIDAEVISTMIAVKEDDFLVFVTNKGLVKRSALSNFNR-NK--NGK---IAIKFRDDD
ELVAVR-T---DG-KHILIGTSQASLIRFKE--IRAMRASGVKGITLR---DVIGLGVADETDEILVVTEKGYGKRTPIGEYRLSRRGGMGIKTANITNG
K-LVCIATVED-EDIMVVTDHGVIIRMEVEDISVNGRNTQGVRLIRLDDD--QFVSTVAKVK--------------------------------------
------------
>tr|R8APA4|R8APA4_PLESH DNA gyrase subunit A OS=Plesiomonas shigelloides 302-73 GN=gyrA PE=3 SV=1
-------HDTILCFSSRGRLYWLKVYQLPLASRGARGRPIVNLLP-ERITAIL--PDDQYIFMATANGTVKKTPLTDFSR-RS--AGI---IAVNLNDDD
TLIGVDLT---HGNDEVMLFSAEGKVVRFAEDQVRPMRATGVRGIKLS---QVVSLIVPKGDGEILTVTANGYGKRTASAEYPTKSRATQGVISI--SNG
L-VVGAVQVE-NDQIMIITNAGTLVRTRVKEVSVVGRNTQGVTLIRTSE-E-EQVVGLQRIL--------------------------------------
------------
>tr|A0A077PM47|A0A077PM47_XENBV DNA gyrase subunit A OS=Xenorhabdus bovienii str. kraussei Quebec GN=gyrA PE=3 SV=1
-------HDTILCFSNKGKMYWMKVYQLPEASRGARGRPIVNLLP-ERITAIL--PDGLNIFMATASGTVKKTKLSEFSR-RS--AGI---IAVKLNDGD
ELIGVDLT---DGSNEVMLFSAKGKVVRFLEEGVRAMRAAGVRGIKLS---GVVSLIIPRGEGEILTVTENGYGKRTAQSEYPTKSRATQGVISI--SNG
N-VIGAIQVE-TDQIMMITDAGTLVRTRVSEVSVVGRNTQGVTLIRTAE-D-EKVVGLQRVA--------------------------------------
------------
>tr|D2U4I6|D2U4I6_9ENTR DNA gyrase subunit A OS=Arsenophonus nasoniae GN=gyrA PE=3 SV=1
-------HDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLP-ERITAIL--PDGHYVFMATASGTVKKTSLKDFSR-RS--AGI---IAVNLNEGD
ELIGVDLT---AGKNEVMLFSAGGKVVRFAENAVRPMRATGVRGIKLH---GVVSLIVPRGEGDILTVTENGYGKRTEQSEYPTKSRATQGVISI--SNG
N-VVGAIQVE-TDQIMMITDAGTLVRTRVAEVSIVGRNTQGVTLIRTAE-D-EKVVGLQRVV--------------------------------------
------------
>tr|A0A0R1RK28|A0A0R1RK28_9LACO DNA gyrase, A subunit OS=Lactobacillus rossiae DSM 15814 GN=FD35_GL001126 PE=4 SV=1
-------HDRLMMFTNTGKVYAMKGYEIPEYGRTAKGIPVINLLGDERIQAVINVKSNNYLFFTTVHGVVKRTAVSEFSN-RS--NGL---KAINLHDGD
ELMNVS-T---DG-QNMIIGTHLGYAVSFAE--VRDMRAAGVRGIRLR---DVVGADVLKPDSHVLVISEKGYGKQTKASEYPIKGRGGKGIKTVNVTNG
P-LTGLTTVST-EDIMLVTNKGVMIRFSIDSVSETGRAALGVHLIRIDED--ASVATMAKVE--------------------------------------
------------
>tr|I2F081|I2F081_EMTOG DNA gyrase subunit A OS=Emticicia oligotrophica (strain DSM 17448 / GPTSA100-15) GN=gyrA PE=3 SV=1
-------HNYLLIFTRKGRLFWMRVFEVPEGSKTSKGRAIQNLINADKIQAVLNVKSNNYIVMCTEDGTVKKTLLEAYSR-RQ--GGI---IAININEGD
NLLDVALT---NGDNDIVIAARNGKVVRFH---TRPMRATGVRGINLE---DAIGMVCVSRETQLLVVSDKGYGKRSDVDEYRITSRGAKGVKTLNITTG
N-LVAIKEVT-DDDLMIITKKGVAIRIKVSDLRVMGRNTQGVKLIRMSD-T-DDIASVTRII--------------------------------------
------------
>tr|E4RR46|E4RR46_LEAB4 DNA gyrase subunit A OS=Leadbetterella byssophila (strain DSM 17132 / KACC 11308 / 4M15) GN=gyrA PE=3 SV=1
-------HNYLLFFTEKGRLYWLRVFEVPEGNKTSKGRAIQNLINSDKIRAVLNVKKNNYIVMCTQNGIVKKTLLEMYSR-RQ--NGI---IAININEGD
QLIDVALT---NGNDYIIIAAGQGKAVRFH---IRPMRATGVKGISLA---DAIGMICVNRDAQLLVVSEKGYGKRSDIEDYRITSRGAKGVKTLNMSVG
N-LVAIKEVT-EDDLMIITTRGIAIRMHVSDLRVMGRNTQGVRLIKLND-K-DGIASITRII--------------------------------------
------------
>tr|F8EKT8|F8EKT8_RUNSL DNA gyrase subunit A OS=Runella slithyformis (strain ATCC 29530 / DSM 19594 / LMG 11500 / NCIMB 11436 / LSU 4) GN=gyrA PE=3 SV=
-------LNYLLIFTEFGKLFWLKVYEIPEGSKTAKGRPIQNLINSDKVRAVINVRNNNYIIMCTEEGTIKKTLLEAYSR-RA--NGI---AAITINEGD
RLLDVALT---NGDNQIIIASKEGKAVRFH---VRPMRAAGVKGIELGET-NAIGMLCVSNEKQLMVVSENGYGKRSQIEDYRETNRGAKGVTTLNITVG
S-LVAIKEVS-SDDLMIINKSGIAIRMSVTEIRVAGRNTQGVRLIKLNE-G-DEISSVTRIE--------------------------------------
------------
>tr|C6W441|C6W441_DYAFD DNA gyrase subunit A OS=Dyadobacter fermentans (strain ATCC 700827 / DSM 18053 / NS114) GN=gyrA PE=3 SV=1
-------LNYLLIFTEYGKLFWMKVYEVPEGSKTSKGRPIQNLISSDSIRSVINVKNNNYLIMCTEQGTIKKTLLEAYSR-RT--NGI---IAISINEGD
RLLNVALT---NGDNDIVIASAAGRAVRFN---VRPMRAAGVRGINLNP--NVIGMVCISRDAQLLVVSENGFGKRSAIDSYRVTNRGGKGVSTMNATVG
K-LVAIREVT-EDDLMIITRNGIAIRMSVLDIRQAGRNTQGVKLIRLSS-S-DEITSVTRIL--------------------------------------
------------
>tr|H1YDQ5|H1YDQ5_9SPHI DNA gyrase subunit A OS=Mucilaginibacter paludis DSM 18603 GN=gyrA PE=3 SV=1
-------HNYMLFFTESGQCFWLRVFEIPEGTRTSKGRAIQNIINKENIKAYIKLTENNFIIMCTRKGVIKKTSLEAYSR-RA--NGI---NAININEGD
TLLQATLT---TGSSEIVMALKSGRAIRFN---VRPMRATGVRGITLAE--DVVGMIAIDDETTVLVVSEKGYGKRTDIEDYRVTNRGGKGVKTINVTTG
Q-LVAIKGVT-EHDLMIINRSGIIIRISMNQLRTMGRATQGVRLISLKE-N-DSIASVAQVE--------------------------------------
------------
>tr|H8KVL8|H8KVL8_SOLCM DNA gyrase subunit A OS=Solitalea canadensis (strain ATCC 29591 / DSM 3403 / NBRC 15130 / NCIMB 12057 / USAM 9D) GN=gyrA PE=3 S
-------HNYMLFFTEKGRCFWLKVYGIPEGSRTSKGRAMQNLIQSDKVKAFITVKESNYIMMCTKQGTIKKTTLEAYSR-RV--TGI---NAITVNEGD
QLLEARLT---TGNSEILMALKSGRAIRFN---VRPMRAAGVRGVTLSV--DVVGMIAVEDETNILVVSEKGYGKRSDIEEYRVTNRGGKGVKTINVTTG
Q-LIAIKDVK-SDDLMIINKSGITIRIGVDELRVMGRATQGVRLIKLNE-D-DEIASVAKIE--------------------------------------
------------
>tr|A0A0M2XZ75|A0A0M2XZ75_9SPHI DNA gyrase subunit A OS=Sphingobacterium sp. Ag1 GN=gyrA PE=3 SV=1
-------HNYMLLFTEAGRCFWLRAFEIPEGSRTSRGRALQNIINKEKIKAFILVKENNFIIMCTKKGTIKKTSLEAYSR-RA--NGI---NAININEGD
QLIEACLT---TGSSEIVMALRSGRAIRFN---VRPMRATGVRGITLAE--DVIGMISVNDETTVLVVSEKGYGKRTDIEDYRVTNRGGKGVKTINVTTG
E-LVAIKGVT-NEDLMIINKSGIVIRIAVEELRVMGRATQGVRLINLKD-N-DEIASITKVD--------------------------------------
------------
>tr|F0SBI6|F0SBI6_PSESL DNA gyrase subunit A OS=Pseudopedobacter saltans (strain ATCC 51119 / DSM 12145 / JCM 21818 / LMG 10337 / NBRC 100064 / NCIMB 1
-------HNYLLFFTDQGKCYWLRVFEIPEGSRTSKGRAIQNIINKEKIKAYIKVVENNFIIMCTKKGTIKKTTLEAYSR-RS--NGI---NAININEGD
ELLEASLT---TGNSEIVMALRSGRAIRFN---VRPMRATGVRGISLAD--DVVGMISIDSESTVLVVSEKGYGKRTDIEDYRVTNRGGKGVKTINITTG
Q-LVAIKSVT-NDDLMIINRSGIVIRIAMDTLRVMGRATQGVRLITLKE-S-DEIASVTKTE--------------------------------------
------------
>tr|F4C701|F4C701_SPHS2 DNA gyrase subunit A OS=Sphingobacterium sp. (strain 21) GN=gyrA PE=3 SV=1
-------HNYMLFFTEAGRCFWLRAFEIPEGTRTSRGRAIQNIINKEKIKAYIKVKENNFIIMCTKGGTIKKTSLEAYSR-RA--NGI---NAININEGD
QLLEACLT---NGNSEIVMALKSGRAIRFN---VRPMRATGVRGVTLAP--DVVGMISVNTDATILVVSEKGYGKRTDIDDYRVTNRGGKGVKTLNVTTG
L-LVAIKDVT-NDDLMIINRSGIVIRIAVSQLRVMGRATQGVRLINLKE-N-DQIASITKVD--------------------------------------
------------
>tr|A0A0Q5MYF2|A0A0Q5MYF2_9SPHI DNA gyrase subunit A OS=Pedobacter sp. Leaf176 GN=ASF92_16860 PE=4 SV=1
-------HNYMLFFTEAGRCFWLRVYEIPEGTRTSKGRAIQNIINKEKIKAYIKVKENNFIIMCTKQGTIKKTSLEAYSR-RV--NGI---NAININEGD
VLLEACLT---NGQSEIVMALRSGRAIRFN---VRPMRATGVRGVRLAD--DVVGMIAVNNEVTVLVVSEKGYGKRTDIEDYRVTNRGGKGVKTINVTTG
Q-LVSIKDVT-SEDLMIINRSGIVIRIPVSALRVMGRATQGVRLISLKG-D-DEIASVTKID--------------------------------------
------------
>tr|A0A0B8XQJ1|A0A0B8XQJ1_9SPHI DNA gyrase subunit A OS=Pedobacter glucosidilyticus GN=gyrA_2 PE=3 SV=1
-------HNYLLFFTDKGKCYWLRVFEIPEGTRISKGRALQNIINKEKIRAYIKVVENNFIMMCTKKGTIKKTTLQAYSR-RT--NGI---NAININDGD
ELLEANLT---TGSSEIIMALRSGRAIRFN---VRPMRATGVRGLRLAD--DVVGMISIDSEATILVVSEKGYGKRTDLEDYRVTNRGGKGVKTIKVTTG
E-LVAIKDVT-KDDLMIINKSGIVIRIAMSHLRVMGRATQGVRLINLKA-N-DEIASVAKVE--------------------------------------
------------
>tr|A0A081PLV7|A0A081PLV7_9SPHI DNA gyrase subunit A OS=Pedobacter antarcticus 4BY GN=gyrA PE=3 SV=1
-------HNYMLFFTESGRCFWLRVYEIPEGSRLSKGRAIQNIINKEKIKAYIKVKENNYIIMCTKKGTIKKTSLEAYSR-RV--NGI---NAININEGD
QLLEASLT---SGSSEIVMALRSGRAIRFN---VRPMRATGVRGVTLGA--DVVGMIAVDDEATVMVVSEKGYGKRTDIEDYRVTNRGGKGVKTITITTG
D-LIAIKSVT-NDDLMIINKSGIVIRIVLSQLRVIGRATQGVRLINLKG-N-DAIASVAKIE--------------------------------------
------------
>tr|R9GXI4|R9GXI4_9SPHI DNA gyrase subunit A OS=Arcticibacter svalbardensis MN12-7 GN=gyrA PE=3 SV=1
-------HNYMLFFTEAGRCFWLRVYEIPEGSRTSKGRAIQNIINKENIKAYIKVKENNFIIMCTAKGTIKKTSLMAYSR-RS--NGI---NAININEGD
QLLEANLT---DGKSEIVMALRSGRAIRFN---VRPMRATGVRGVTLAD--DVIGMLSINNEATVLVVSEKGYGKRTNLEDYRVTNRGGKGVKTLNVTTG
D-LIAIKDVT-TDDLMIINKSGIVIRIAISALRVMGRATQGVRLISLKG-D-DAIASIAKVE--------------------------------------
------------
>tr|A0A081NAP7|A0A081NAP7_9GAMM DNA gyrase subunit A OS=Endozoicomonas montiporae GN=gyrA PE=3 SV=1
-------HTQILCFSSKGKVYWLKVYQIPEAGRTSRGRPIVNILP-ERITAMLPVEEGHYVFMATAQGTVKKTPLEQFSRPRT--SGL---IALGLEEGD
TLVGAQIT---DGEKQVMLLSNAGKAIRFEETDVRQVRARGVRGIKLHDQR-VISLIIPE-GAQILTASENGFGKRTCVEDFRITGRGGQGVISMQCTNG
H-IVGAIQVQDGEEVMLISDQGTLVRTRVDEISVMSRNTQGVTLIKVQ-EG-EKLVGVARVE--------------------------------------
------------
>tr|A0A081NH39|A0A081NH39_9GAMM DNA gyrase subunit A OS=Endozoicomonas numazuensis GN=gyrA PE=3 SV=1
-------HTQILCFSSKGKVYWLKVYQIPPAGRTSRGRPIVNILP-ERITAMLPVEEGHFVFMATVAGTVKKTPLEQFSRPRS--SGL---IALGLDEGD
SLVGAQIT---TGEKQVMLLSNSGKAIRFEETDVRAMRARGVRGMKLQEQR-VISLIIPE-ETQILTVSQNGFGKRTGVEDFRITGRGGQGVISMQCTNG
E-LIGSIQVRDGEEIMLISDQGTLVRTRVDEISVMSRNTQGVTLIKVQ-EG-EKLVGVARVE--------------------------------------
------------
>tr|A0A081KBT9|A0A081KBT9_9GAMM DNA gyrase subunit A OS=Endozoicomonas elysicola GN=gyrA PE=3 SV=1
-------HTQILCFSSKGKVYWLKVYQIPQAGRTSRGRPIVNILP-EKITAMLPVEEGYFVFMATMNGTVKKTPLEQFARPRS--SGL---IALGLDEGD
TLVGAEIT---TGEKQVMLLSNGGKAVRFEETGVRAMRARGVRGMKLPEQR-IISLIIPE-DTQILTASAKGFGKRTSVDEFRLTSRGGQGVISMQCTNG
E-IVGAIQVKSGEQIMLISDQGTLVRTGVDGVSSLGRNTQGVTLIRVS-EG-EKLVGVARVE--------------------------------------
------------
>tr|Q2SCF1|Q2SCF1_HAHCH DNA gyrase subunit A OS=Hahella chejuensis (strain KCTC 2396) GN=gyrA PE=3 SV=1
-------HDTILCFTSHGKLYWLKTYEIPQASRISRGRPIVNILP-ERITTMLPVRADHYVFMATRQGTVKKTPLENFSRPRS--SGL---IALALDEGD
MLIGAAIT---DGKKDVMLFSSSGKAIRFNEDDVRPMRARGVRGIRLAQQT-VVSLIIPQ-DAYILTASRKGYGKRTAVSEFPVYGRGGQGVIAIQCSNG
D-LVSAVQVISGDQLMLISNQGTLVRTRSDEVSIVGRNTQGVRLIRLS-ES-EDLVGVERIA--------------------------------------
------------
>tr|A0A0A3AKB0|A0A0A3AKB0_9PAST DNA gyrase subunit A OS=Chelonobacter oris GN=gyrA PE=3 SV=1
-------HDTILCFSSRGRLYWLRVFQLPQASRGARGRPIVNILP-ERITAIL--PENKYIFMATASGTVKKTALTEFSR-RA--SGL---IAINLRDND
ELIGVDIT---EGNNEIMLFSSQGRVVRFSEEAVRAMRATGVRGIRLATDSIVVSLVVPKNDGAILTATQNGYGKRTLLGEYPAKSRNTKGVISI--SNG
K-VVAAVQVA-NDQIMLITDAGTLVRTRVSEVSTIGRNTQGVRLIRTAE-N-EHVVGLEKVC--------------------------------------
------------
>tr|A0A0A2XKV9|A0A0A2XKV9_9PAST DNA gyrase subunit A OS=Gallibacterium genomosp. 2 GN=gyrA PE=3 SV=1
-------HDTILCFSSRGRLYWLKVYQLPQASRGARGRPIVNLLP-ERITAIL--PEDKFIVMATAGGLVKKTTLTEFSR-RT--SGI---IAVNLRDDD
ELIGADIT---EGNNEIMLFSAQGRVVRFDENAVRAMRAAGVRGIKLATDSIVVSLVIPKTNGAILTATQNGYGKRTALAEYPTKSRNTKGVISI--SNG
K-VVAATQVE-NDQIMLITDAGTLVRTRVAEISLVGRNTQGVRLIRTSD-T-EQVVSIERIC--------------------------------------
------------
>tr|A0A0K6GVK4|A0A0K6GVK4_9GAMM DNA gyrase subunit A OS=Idiomarina woesei GN=gyrA PE=3 SV=1
-------HDTILCFSTRGRIYWMKVYQLPLATRTSRGRPIVNLLP-ERITAIL--PDDKYIVMATRNGTVKKTPMEAYSR-RS--GGI---IALNLNDGD
ELIGVDVT---TAGDEVMLFSDAGKVVRFSEEQIRSMRATGVRGIRLE---GVVSLIVPRTVPTILTVTENGYGKRTPITDYPAKSRATKGVVSI--SNG
L-VVGAMEVV-ANQIMLISNKGTLVRTRVNEVSVVGRNTQGVRLIRTGA-D-EKVVGMQRID--------------------------------------
------------
>tr|W7QIX3|W7QIX3_9ALTE DNA gyrase subunit A OS=Catenovulum agarivorans DS-2 GN=gyrA PE=3 SV=1
-------HDTILCFSDRGRLYWLKVYQLPLATRTARGKPIVNLLP-ERISAIL--PEDKFIIMATANGTVKKTRLTEYSR-RA--NGI---IALNLNEGD
HVIGVDIT---HGDSDILLFSDAGKVVRFNEQQVRPMRATGVRGIKLD---TVVSMIVPHGDGAVLTVTENGYGKRTPLEEYPAKSRATLGVVSI--SNG
S-VVGAVQVN-GDEIMMITNKGTLVRTRVGEVSVIGRNTQGVRLIRTAD-G-ELVVGLQRIE--------------------------------------
------------
>tr|A0A094IXY6|A0A094IXY6_9GAMM DNA gyrase subunit A OS=Idiomarina salinarum GN=gyrA PE=3 SV=1
-------HDTILCFSTRGRIYWMKVYQLPLATRISRGRPIVNLLP-ERITAIL--PEDKFVVMATRNGTIKKTPLVDYSR-RN--GGI---IALNLMPND
ELIGVDLT---SAGDEIMLFSDGGKVVRFSEDQVRSMRATGVRGIRLA---DVVSLIVPRTVPTILTVTENGFGKRTPITDYPAKSRATKGVVSI--SNG
S-VVGAMEVI-TNQIMLISNKGTLVRTRVSEVSVVGRNTQGVRLIRTGA-D-EKVVGMQRID--------------------------------------
------------
>tr|A3WL75|A3WL75_9GAMM DNA gyrase subunit A OS=Idiomarina baltica OS145 GN=gyrA PE=3 SV=1
-------HDTILCFSTRGRIYWMKVYQLPLASRASRGKPIVNLLP-ERITAIL--PEDKFVIMATKHGTVKKTPLPEYSR-RN--GGI---IALNLNEGD
ELIGVDIT---DGEQEIMLFSDGGKVVRFREDQVRSMRATGVRGIRLE---GVVSLIVPGTQAAILTVTENGFGKRTLVEEYPTKSRATKGVVSI--SNG
A-VVGAMEVV-GNEIMLISNKGTLVRTRVNEVSMVGRNTQGVRLIRTGD-D-EQVVGLQRID--------------------------------------
------------
>tr|K2KWR0|K2KWR0_9GAMM DNA gyrase subunit A OS=Idiomarina xiamenensis 10-D-4 GN=gyrA PE=3 SV=1
-------HDTILCFSTLGRIYWMKVYQLPLATRISRGRPIVNLLP-ERITAIL--PEDKFVVMATRNGTVKKTPLVDYSR-RN--GGI---IALNLVDDD
ELIGVDIT---DGGDEIMLFSDGGKVVRFTEDQVRSMRATGVRGIRLE---GVVSLIVPRAEPKILTVTANGFGKRTGITQYPAKSRATKGVVSI--SNG
P-VVGAMEVI-GNEIMLISNKGTLVRTRVNEVSTVGRNTQGVRLIRTAD-D-ETVVGLQRID--------------------------------------
------------
>tr|J3HEE4|J3HEE4_9PSED DNA gyrase subunit A OS=Pseudomonas sp. GM74 GN=gyrA PE=3 SV=1
-------HTTLLLFSSKGKVYWLKTYEIPEASRAARGRPLVNLLP-EYITTMLPVEEGHYIFMATANGTVKKTPLESFSRQRS--VGL---IALELDEGD
VLISAAIT---DGEREVMLFSDGGKVTRFKESDVRAMRARGVRGMRLPEQK-LISMLIPEEGSQILTASARGYGKRTAITEFPEYKRGGQGVIAMVSNNG
R-LVGAVQVLDGEEIMLISDQGTLVRTRVDEVSSLGRNTQGVTLIKLA-ND-ETLVGLERVQ--------------------------------------
------------
>tr|A0A0F9WIZ7|A0A0F9WIZ7_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_0350510 PE=3 SV=1
-------HTTLLLFSSRGKVYWLKTYEIPEASRTARGRPLVNLLP-EFISTMLPVDEGWFIFMATANGTVKKTPLVQFSRQRS--VGL---IALDLDEGD
TLISAALT---NGEREIMLFSDGGKVTRFKETDVRAMRARGVRGMRLPAQH-LVSMLIAEAGTQILTASSRGFGKRTAVEDFPQYKRGGQGVIAMVSNNG
P-LVGAVQVVDGEEIMLISDQGTLVRTRVNEVSCLSRNTQGVMLIRLA-SD-EKLVGLERVQ--------------------------------------
------------
>tr|K4KUY1|K4KUY1_SIMAS DNA gyrase subunit A OS=Simiduia agarivorans (strain DSM 21679 / JCM 13881 / BCRC 17597 / SA1) GN=gyrA PE=3 SV=1
-------HTTILLFTNAGKVYWLKVYEIPLAGRQSRGRPVVNLLP-ERVTSILPVDDDHFIFMATANGTVKKTALTQFSRPRS--VGL---KAIELDEGD
QLVETAIT---DGKQTIILFASTGKAARFAEDDVRSMRSRGVRGIRMP--EGVVGMVVPQENGYVLTVSENGYGKRTQVDEFPTKGRGSQGVIAMASSNG
A-LVGAVQVMDGEEIMLISDLGTLVRTRVDEVSVLSRNTQGVRLIKVK-DG-EQLVGVERIA--------------------------------------
------------
>tr|A0A078M8V7|A0A078M8V7_9PSED DNA gyrase subunit A OS=Pseudomonas sp. 12M76_air GN=gyrA PE=3 SV=1
-------HTTLMLFSSKGKVYWLKTYEIPEASRTARGRPLVNLLP-EYITTMLPVEEGWFIFMATANGTVKKTPLPQFSRQRS--VGL---IALDLDEGD
TLISAALT---DGNKQIMLFSDGGKVTRFNETDVRAMRARGVRGMRLPEQR-LVSMLIAEDGTEILTASQHGYGKRTPVEDFPQYKRGGQGVIAMVTNNG
P-LVGAVQVVEGEEIMLISDQGTLVRTRVSEVSSLSRNTQGVTLIKLG-NG-EKLVGLERVQ--------------------------------------
------------
>tr|A0A0F9XAD2|A0A0F9XAD2_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_0172010 PE=3 SV=1
-------HTTLMLFSSKGKVYWLKTYEIPEASRTARGRPLVNLLP-EYITTMLPVDEGWFVFMATANGTVKKTPLEQFSRQRS--VGL---IALDLDEGD
TLISATIT---NGEREIMLFSDGGKVTRFKETDVRAMRARGVRGMRLATQR-LVSMIVAEEGTQILTASQRGFGKRTNVEEFPQYKRGGQGVIAMVSNNG
P-LVGAVQVVAGEEIMLISDQGTLVRTRVSEVSSLSRNTQGVTLIKLS-NG-EKVVGLECVQ--------------------------------------
------------
>tr|I3ID33|I3ID33_9GAMM DNA gyrase subunit A OS=Cellvibrio sp. BR GN=gyrA PE=3 SV=1
-------HDTVLLFTNAGKVYWLKVYMIPVAGRQSRGRPVINLLPEEHITSILPVKDDKFIFMTTANGTVKKTALTQFSRQRS--VGL---RAIELDEGD
TLVGTAIT---NGSCDVILFSSSGKAARFRESQVRAMRSRGVRGIRLAEQR-VVGMVIPM-NGQVLTVSENGYGKRTEVGEFPAKGRGSQGVIGMQTTNG
Q-LVGAVQVFDGEEIMLISDQGTMVRTRVDEVSVLSRNTQGVRLIKLK-EG-ERMQGLERIE--------------------------------------
------------
>tr|D4ZUF9|D4ZUF9_ARTPN DNA gyrase subunit A OS=Arthrospira platensis (strain NIES-39 / IAM M-135) GN=gyrA PE=3 SV=1
-------HDSILFFTERGVAYCLKAYQIPIGSRIARGVPIVQMLPREKITSLVAVGNDEYLVMLTKGGYIKKTALSAFSNIRS--NGL---IAISLNEGD
ELRWVRSA---RVDDSIIIGSRLGMAIHFHT--LRPLRTRGVKSMKLK---DLIGMDILPSGVSILVITTRGYGKRVPVSQFRLQNRAGKGIIATKFHGD
C-VVALQVVH-TDELMLITSRGIIIRQVISAISRQSRNATGVRVQRLDK-E-DAIAAVALVP--------------------------------------
------------
>tr|U7QQT2|U7QQT2_9CYAN DNA gyrase subunit A OS=Lyngbya aestuarii BL J GN=gyrA PE=3 SV=1
-------HDSILFFSDRGVVYCLKAYQIPVASRTARGVPIVQMLPKERITSVVPVSDDDYLVMLTKGGYIKKTELSAFSNIRA--NGL---IAISLGEGD
ELRWVRLA---KADDSIIIGSRLGMAIHFRT--LRPLRTRGVKSMKLG---DLISMDILPSELAIMVITAGGYGKRVPVSQFRLQNRAGKGIIATKFHTD
E-VVGLQVVN-DNELMLITSRGIIIRQAVNAIPTQSRSATGVRVQRLDD-E-DAIAAVAIVP--------------------------------------
------------
>tr|F7XY92|F7XY92_MOREP DNA gyrase subunit A OS=Moranella endobia (strain PCIT) GN=gyrA PE=3 SV=1
-------HETILLFSNRGRMYWLKVYQLPEARRSARGRPIVNLLP-ERITAILPVRYGYHIFMATANGTVKKTSVINFRRQRS--TGI---TAINLNHGD
ELIGVDLT---NGNDDVMLFSTHGKVVRFPETQVRSMRATGVLGINLA--EDVVSLIVPRS-GTILTVTQHGYGKRTVPAEYPTKSRATQGVISIKVSNG
E-VVGAVQVEDYDQIMMITNTGNLVRMRVSEVKIVGRNTNGVTLIRTA-QN-ENVVGLQRIA--------------------------------------
------------
>tr|R5FP64|R5FP64_9BACT DNA gyrase subunit A OS=Prevotella sp. CAG:924 GN=gyrA PE=3 SV=1
-------HQTMLFFTKKGRCYWLKCYDIPEGDKTSKGRAIQNLLDPDAVNAFLRLRNSHYVVFATKSGIVKKTCLKQYSN-RS--KGV---IAINILEGD
EVVDVRLT---NGKNELILADRNGRAVRFD---VRAMRSTGVTGMRID---DVVGMIVVNNTETVMVVSENGYGKRSMVE-YRKTNRGTRGVKTLNITTG
R-LVAIKNVT-ENDLMIINKSGITLRLPVQEIRVIGRTAQGVHLINLTKKN-DSIASVCKVM--------------------------------------
------------
>tr|D1PUI7|D1PUI7_9BACT DNA gyrase subunit A OS=Prevotella bergensis DSM 17361 GN=gyrA PE=3 SV=1
-------HQTMMFFTKKGRCYWLHCYDIPEGDKTSKGRAIQNLLNPDSVNAFLRLRNSHYVVFATKNGTVKKTNLKEYSR-RA--NGV---IAINIVEGD
EVVDVRLT---NGNNELILANRNGRAVRFD---IRSMRSTGVRGMRID---DVVGMIVVNNTETVMVVSEEGYGKRSDVA-YRKTNRGGKGVKTMSITTG
R-LVAIKNVT-ENDLMIINKSGIVIRLAVAEVRVMGRATQGVRLINLARKN-DTIASVCKVM--------------------------------------
------------
>tr|F8NCM9|F8NCM9_9BACT DNA gyrase subunit A OS=Prevotella multisaccharivorax DSM 17128 GN=gyrA PE=3 SV=1
-------HQTMLIFTRLGRCYWLHCYDIPEGDKASKGRAIQNLLNSDTVNAFLRLRNSHYVVFATKNGTVKKTCLKEYSR-RA--NGV---KALIIADGD
EVVDVRLT---NGSNELILADRNGRAVYFD---VRPSRAMGVRGMVLD---DVVGMIVVNNKETAMVVSENGYGKRSEIV-YRKTSRAKKGVKTIAITTG
K-LVAIKNVT-ENDLMIINKSGIVIRMAVADVRVMGRATQGVRLINLTKKN-DCIASVCKVM--------------------------------------
------------
>tr|F9D5B6|F9D5B6_PREDD DNA gyrase subunit A OS=Prevotella dentalis (strain ATCC 49559 / DSM 3688 / JCM 13448 / NCTC 12043 / ES 2772) GN=gyrA PE=3 SV=1
-------HQTMLFFSKKGRCYWLHCYDIPEGDKTSKGRAIQNLLNPDSVNAFLRLRNSHYVVFATKNGTVKKTSLKEYSR-RA--NGV---IAINIVEGD
EVVDVRLT---NGENELVMANRNGRAVRFD---IRTMRSTGVRGMRLD---DVVGMVVVNDSESVMVVSENGYGKRSGVE-YRKTNRGGKGVKTMAVTTG
R-LVAIKNVT-DNDLMIINKSGIVIRMAVSDIRVMGRATQGVRLINLAKKN-DIIASVCKVM--------------------------------------
------------
>tr|I4VP45|I4VP45_9GAMM DNA gyrase subunit A OS=Rhodanobacter fulvus Jip2 GN=gyrA PE=3 SV=1
-------HDTLLTFTSTGRVYWLNVYQIPEASPGARGKPIVNLLP-EHVQAVLPIRDDRYVFFATRQGTVKKTPLGEFAFQLQ--KGK---LAIRLNEDD
ALVNVELT---DGNSDILLFASNGKVNRFDENTVRSMRAAGVRGMKLAK--AVVSLIVA-AEGDILTATERGYGKRTPLVEFTKKGRGTQGVIGIQCSNG
A-LVAAAQVTEEHELMLISDQGTLVRTRVAEVSQLGRNTQGVTLIRLP-AD-EKLVSVMRLD--------------------------------------
------------
>tr|A0A0K8QNZ4|A0A0K8QNZ4_9GAMM DNA gyrase subunit A OS=Mizugakiibacter sediminis GN=gyrA PE=3 SV=1
-------HDTLLTFTSAGRVFWLRVYQIPEAGPGARGKPIVNLLP-EKVQAVLPVRDQHYVLFATRNGTVKKTPLTEYAYRLQ--RGK---IAINLDDGD
ALVDVQLT---DGHRDVMLFASNGKAVRFAEDEVRPMRATGVRGMKLAE--EVVSLVVTEGDGDILTATARGYGKRTPLAEYPRKGRGTQGVIAIQCSNG
A-LVAAVQVDGAHELMLISNLGTLVRTRVAEVSQLGRNTQGVTLIRLP-AE-ESLVGAVRVE--------------------------------------
------------
>tr|A0A075K227|A0A075K227_9GAMM DNA gyrase subunit A OS=Dyella japonica A8 GN=gyrA PE=3 SV=1
-------HDTLLTFTSTGRVYWLNVYQMPESGPNARGKPMVNLLP-EKVQAVLPVREDRFVFFATKQGTVKKTPLTEFAFQLQ--KGK---IAINLDEGD
ALVNVALT---DGNSDVLLFASNGKTVRFDESEVRSMRATGVRGMKLAD--AVVSLIVA-AEGDILTATERGYGKRTQLDEFPKKGRGTQGVIGIQCSNG
P-LVAATQVTEAHEMMLISDQGTLVRTRVAEVSQLSRNTQGVTLIRLP-AD-EKLVSVVRLD--------------------------------------
------------
>tr|A0A0Q9PSQ4|A0A0Q9PSQ4_9GAMM DNA gyrase subunit A OS=Frateuria sp. Soil773 GN=ASG87_18070 PE=4 SV=1
-------HDTLLTFTSTGRVYWLKVYQMPESGPSARGKPMVNLLP-EKVQAVLPIREDRYVFFATRHGTVKKTPLSEFAFQLQ--RGK---IAINLDEGD
ALVDVALT---DGNSDVLLFASNGKVNRFDENTVRSMRATGVRGMRLAE--AVVSMIVA-AEGDVLIATERGYGKRTQLDEFAKKGRGTQGVIGIQCSNG
P-LVAAVQVTEAHELMLISDQGTLVRTRVAEVSQLGRNTQGVTLIRLP-AD-EALVSVVRLE--------------------------------------
------------
>tr|A0A0Q8LFY6|A0A0Q8LFY6_9GAMM DNA gyrase subunit A OS=Rhodanobacter sp. Root179 GN=ASD82_16420 PE=4 SV=1
-------HDTLLAFTSTGRVYWQKVYQIPESGPGARGKPIINLLP-EKVQAVLPIREDRFVFFATRHGTVKKTPLSEFAFQLQ--KGK---LAIKLHDDD
ALVNVELT---DGNSDILLFASNGKVNRFDENTVRSMRASGVRGMKLVG--AVVSLIVA-AEGDILTATARGYGKRTELAEFTKKGRGTQGVIGIQCSNG
A-LVGAVQVTEAQELMLISDQGTLVRTRVAEVSQLGRNTQGVTLIKLP-AD-ETLVSVMRLD--------------------------------------
------------
>tr|A0A0G9H3S3|A0A0G9H3S3_9GAMM DNA gyrase subunit A OS=Luteibacter rhizovicinus DSM 16549 GN=gyrA PE=3 SV=1
-------HDTLLTFTSTGRVYWLKVYQMPEAGPGARGKPIVNLLP-EKVQALLPVRPTCFVFFATRKGTVKKTPLTEFAFQLQ--KGK---AAINLDEGD
ALVDVAMT---GGESDILLFASNGKSVRFDEGTVRSMRATGVRGMRLAD--AVVSLIVAAGEGDILTATARGFGKRTTLDEFPKKGRGTQGVIAIQCSNG
S-LVAATQVTETQQLMLISDQGTLVRTRVSEVSQLSRNTQGVTLIKLP-KD-ETLIGVVRLE--------------------------------------
------------
>tr|H8L3W9|H8L3W9_FRAAD DNA gyrase subunit A OS=Frateuria aurantia (strain ATCC 33424 / DSM 6220 / NBRC 3245 / NCIMB 13370) GN=gyrA PE=3 SV=1
-------HDTLLTFSSTGRVYWLKVYQMPEAGSGARGKPIVNLLP-ETVQAVLPVREDQFVFFATRKGTVKKTPLTEFAYQLQ--KGK---IAINLDESD
ALVGVALT---DGESDVLMFASNGKTVRFDEGEVRSMRAGGVRGMKLAD--AVVSMIVA-REGDILTATERGYGKRTPLDEFPKKGRGTQGVIGIQCSNG
P-LVAAVQVTEAHELMLISNQGTLVRTRVAEVSQLSRNTQGVTLIRLP-AD-EALVRVVRLD--------------------------------------
------------
>tr|I4W995|I4W995_9GAMM DNA gyrase subunit A OS=Rhodanobacter sp. 115 GN=gyrA PE=3 SV=1
-------HDTLLAFTSVGRIYWLKVYQMPEAGPGARGKPMVNLLP-EKVQAVLPIREDRYVFFATRHGTVKKTPLTEFAFQLQ--KGK---IAIKLDEGD
ALVDVELT---DGNSDILLFASNGKVNRFDENTVRSMRATGVRGMKLAD--AVVSLIVA-AQGDILTATERGYGKRTVLDEFPKKGRGTQGVIGIQCSNG
P-LVAAVQVDETHELMLISNQGTLVRTRVAEVSQLSRNTQGVTLIRLP-AD-ESLVSVVRLD--------------------------------------
------------
>tr|S6HJ06|S6HJ06_9GAMM DNA gyrase subunit A OS=Osedax symbiont Rs1 GN=gyrA PE=3 SV=1
-------HDTILCFSNFGKVYWLKVFEIPVASRAARGRPIINILPAERISTILPVNEDRFVFMATASGTVKKTSLVNFARPRS--SGL---IAVDLLDDD
ALIGAAIT---EGDDDILLVTSAGKAARFHETDVRAMRARGVRGVKMKDAK-VISLIIPKEGGKILTASENGFGKQTEVSDFPCKGRGNQGVIGQQCTNG
G-IAGAVQVFTGDDVMLISDQGTMVRTRTSEIGVLGRNTQGVRLIRVV-EG-ESLVGIARIQ--------------------------------------
------------
>tr|B3PII5|B3PII5_CELJU DNA gyrase subunit A OS=Cellvibrio japonicus (strain Ueda107) GN=gyrA PE=3 SV=1
-------HDTILCFTSVGKVYSLKVYMIPEAGRQSRGRPVVNLLPEERITSILPVKNDHFIFMATRKGTVKKTVLTEFQSLRA--NGK---RAIELDEGD
TLVGTAVT---NGACDVILFSSSGKAARFRESQVRAMRSRGVRGIRIAEQF-IVGMVIPL-GGQVLTVSENGYGKRTPVDEFPAKGRGSQGVIGMQTTNG
E-LVGAVQVFDGEEIMLISDQGTMVRTRVDEVSLLSRNTQGVRLIKLK-DG-ERMQGIERIE--------------------------------------
------------
>tr|K9VWL8|K9VWL8_9CYAN DNA gyrase subunit A OS=Crinalium epipsammum PCC 9333 GN=gyrA PE=3 SV=1
-------HDSILFFSDRGVVYCLRAYQIPGASRTSRGVPIVQLLPREKITSIVPVSSEEYLVMLTQGGFIKKTALSAFGNIRA--NGL---IAISLEEGD
QLRWVRRA---RAEESIIIASRQGMAIHFRT--LRPLRTRGVRAMNLR---DLISMDIIPSGLWVLVVTMGGYGKRVPVSQFRLQNRAGKGLIATKFRKD
Q-LISLRVVN-EDELMMITSRGIIIRQSVSAIPSQSREATGVRVQRLDE-D-DAIAAVALVP--------------------------------------
------------
>tr|K9S5I2|K9S5I2_9CYAN DNA gyrase subunit A OS=Geitlerinema sp. PCC 7407 GN=gyrA PE=3 SV=1
-------HDSLLFFSDRGVAYCLRSYQIPTGSRNARGVPIVQMLPHEKITSVVPVSADEYLVMLTKGGYIKKTALAAFSNIRA--NGL---IAISLEDGD
QLRWVRRA---RAEDSVMIGSRKGMVIHFKT--LRPLRTRGVKAMSLR---ELISMDILPAGPWVLVITTGGYGKRVPVGQFRLQNRAGMGLVASKF-DD
Q-LADLRVVG-GAELMMITSRGIIIRQVTDAISCQSRMATGVRVQRLDE-E-DAIAAVALVP--------------------------------------
------------
>tr|K9RP03|K9RP03_SYNP3 DNA gyrase subunit A OS=Synechococcus sp. (strain ATCC 27167 / PCC 6312) GN=gyrA PE=3 SV=1
-------HDQILFFSDRGVVYGLPAYQIPIGSRNARGTPLVQMLPREKITSVIAVQEDEYLVMLTTKGYIKKTALAAFSNIRS--NGL---IAISLEEGD
QLRWVRRA---KVSDSIIIGSRAGMAIHFRA--LRPLRTRGVKSMALR---DLVGMDIIPAGPWVLVVTTNGFGKRVPVNQFRLQNRAGLGLMATKFKAD
Q-LAALRVVN-DDELMIVTSRGIIIRQAVNVISSQSRLATGVRLQRLDE-D-DVIVTAAIVP--------------------------------------
------------
>tr|A0A0M1JYA1|A0A0M1JYA1_9CYAN DNA gyrase subunit A OS=Planktothricoides sp. SR001 GN=gyrA PE=3 SV=1
-------HDKVLFFSERGVVYCLNAYQIPMSSRTAQGSAIVQLLPHEKITSIVPVSDDEYLVMLTQDGYIKKTALSVFNNIRA--NGL---IAISLEEGD
QLRWVRRA---TAEDSIIIGSSNGIAIHFKT--LRPLRTRGVKSMKLA---RIISMDIIPSGQMVLILTTGGLGKRVPVNKFRLQKRAGKGIKAIKF-DD
R-LAALRVVN-DDEFIIVTSRGIIIRQVAKAISCQSRAAGGVRVQRLDP-D-DAIVAVALVP--------------------------------------
------------
>tr|B8HKE2|B8HKE2_CYAP4 DNA gyrase subunit A OS=Cyanothece sp. (strain PCC 7425 / ATCC 29141) GN=gyrA PE=3 SV=1
-------HDGILFFSDRGVAYCLKAYQIPIGSRNARGVPIVQLLPREKITSVVPVDEDEYLVMLTAGGYIKKTALSAFSNIRA--NGL---IAIALETGD
QLRWVRRA---REGDSIIIGSRQGMAIHFRT--LRPLRTRGVRAMALR---DLIGMDILPSGPWVLVVTTCGFGKRVPVSQFRLQNRAGKGITATKFRQD
Q-LAALRIVN-EDELMIVTNRGIIIRQSVGAISSQSRAATGVRLQRLDE-E-DSIAAVTIVP--------------------------------------
------------
>tr|H3NDL6|H3NDL6_9LACT DNA gyrase subunit A OS=Dolosigranulum pigrum ATCC 51524 GN=gyrA PE=3 SV=1
-------HDFLLFFTNKGKVYQAKGYEVPEYGRNAKGIPALNFLNDEKIQTMISMTADRQLFFATRQGTVKRTALSEFEN-RT--SGL---IAINLKEGD
ELVNVV-T---NG-QSIVMGTHDGYAVHFAE--VRSMRATGVRGVRLE---GVIGMEILNSDQDVFVVSENGYGKRTVAAEYAIRNRGGKGVITLNITNG
P-LVALKTVDT-EDIMMVTDQGIMIRFDAQDISQTSRSTQGVRLMRLEDE--SRVATVAKID--------------------------------------
------------
>tr|K9E947|K9E947_9LACT DNA gyrase subunit A OS=Alloiococcus otitis ATCC 51267 GN=gyrA PE=3 SV=1
-------HDQILFFTNQGKVYKIKAYEIPEYGRNAKGIPAINFLNDEYIQAMVNLSDQDQFFFATRFGRVKRTAQAEFQN-RS--SGL---NAIKLNEGD
ELVNVV-T---HN-QAIILASQQGYAVYFDE--IRSMRAAGVRGIRLG---DVVAMEVLEPGQDVLVISEKGYGKRTSQEEYTLHKRGGKGVKTLHITNG
P-LVGLKTVSG-EDVMIVTDQGIMIRIEADSISQTSRLTQGVRLIRLEED--SRVSTVALID--------------------------------------
------------
>tr|A0A011RR67|A0A011RR67_9LACT DNA gyrase subunit A OS=Alkalibacterium sp. AK22 GN=gyrA PE=3 SV=1
-------HDLLLFFTNTGKVYKAKGYEIPEYGRTAKGIPAINFLGDEKIQAIINTR-TDQLFFTTRLGTVKRTAFSEFDN-RN--NGL---KAIVLRDDD
ELIDVS-T---HG-DHIVIGTRQGYAVSFHE--VRSMRASGVRGMRLR---GVVGMDKLSADAEVLIITENGYGKRTPASEYAIRGRGGKGVKTANITNG
P-LIGLKTVTM-EDIMLITKSGVIIRFNSSNISQTGRATQGVRLMKLEEG--NFVSTLAKVE--------------------------------------
------------
>tr|B8F306|B8F306_HAEPS DNA gyrase subunit A OS=Haemophilus parasuis serovar 5 (strain SH0165) GN=gyrA PE=3 SV=1
-------HDTILCFSSCGRLYQLKVYQLPQASRGARGTPIVNILPGERITAILPVPADKFIFMATASGTVKKVSLDAFSN-RS--SGL---IALKLREGD
ELIGVDIT---NGESEIMLFSAQGRVVRFAETAVRGMRATGVRGIKLATITTVVSLVIPHTQGEILTVTQNGYGKRTALGEYPVKSRATKGVVSI--NNG
K-VVAAVQVE-NDQIMLITDAGTLVRTRVNEVSLVGRNTQGVRIIRTAE-D-EHVVSLERIC--------------------------------------
------------
>tr|F7RYR4|F7RYR4_9GAMM DNA gyrase subunit A OS=Idiomarina sp. A28L GN=gyrA PE=3 SV=1
-------HDMILCFSSRGRVYWMKTYNLPYASRAARGKPIVNLLP-ERINAILPIAEDKFVIMATRKGTVKKTPLADYSRPRT--SGI---IALNLTDGD
ELIGVDIT---DGNSEIMLFSDAGKVVRFTEDQVRSMRATGVRGMRIE--PEIVSLLIPRT-GAVLTVTENGYGKRTPLAEYPAKSRATKGVVSIKVSNG
A-VVGAMEVVPGEHLMLISNRGTLVRTRVDEVSQVGRNTQGVTLIRTA-AD-EFVVGMAR-V--------------------------------------
------------
>tr|A0A0P7ZNK1|A0A0P7ZNK1_9GAMM DNA gyrase subunit A OS=Idiomarinaceae bacterium HL-53 GN=gyrA PE=4 SV=1
-------HDMILCFSSLGRVYWMKTYQLPYATRTARGKPIVNLLP-ERITAIL--PDDKFVLMATRNGTVKKTPLVEYSR-RT--SGI---IALNLAEGD
ELIGVDIT---NGESEVMLFSDAGKVVRFHENHVRSMRATGVRGMRIE---EIVSLIIPRLESAILTVTENGYGKRTPLADYPAKSRATKGVVSI--SNG
A-VVGALEVV-GEHLMLISNRGTLVRTRVDEVSQVGRNTQGVTLIRTAE-D-EFVVGIARIA--------------------------------------
------------
>tr|S9ZJV0|S9ZJV0_9RHOO DNA gyrase subunit A OS=Thauera terpenica 58Eu GN=gyrA PE=3 SV=1
-------HDTVLCFSSRGRCYWLKVYEVPEGTRNSRGKPIVNLFP-EKITAVLPIK-EHFVFMATSEGTVKKTALSAFSNPRK--AGI---IAVNLDDGD
HLIGVAIT---GGECDVMLFSDAGKAVRFAE-DVRPMRARGVRGMMLE--DGVIAMLVAEDLLSVLTATENGYGKRTPVAEYTRHGRGTKGMIAIQTSNG
K-LVGAVLVEPSDEVMLISTGGVLIRTSVESIREMGRATQGVTLINLD-EG-TFLASIEKVA--------------------------------------
------------
>tr|W0SFG5|W0SFG5_9RHOO DNA gyrase subunit A OS=Sulfuritalea hydrogenivorans sk43H GN=gyrA PE=3 SV=1
-------HDYILCFSSRGRVYWLKVYEAPEGTRNSRGKPIVNLFP-EKITAILPVK-EHFVFMATAMGTVKKTPLTSFANPRK--AGI---IAVGLDEGD
HLIGVAIT---NGQCDVMLFSDSGKAVRFAE-DVRPMRARGVRGMMLE--DEVISMLVADSNYSVLTATENGFGKRTPIAEYTRHGRGTKGMIAIQTSNG
K-VVAAVLTEPREEIMLISTGGVLIRTRVTDIRVMSRSTQGVTLINLD-DG-THLAGVEKVI--------------------------------------
------------
>tr|A0A0K1J9X8|A0A0K1J9X8_9RHOO DNA gyrase subunit A OS=Azoarcus sp. CIB GN=gyrA PE=3 SV=1
-------HDYILCFSSRGRVYWLKVYEVPEGTRNSRGRPIVNLFP-EKINAVLPVQ-NHFVFMATAEGTVKKTALTAFANPRK--AGI---IAASLDDGD
RLIGVAIT---DGESDVMLFSDAGKAVRFPE-DVRPMRARGVRGMTLE--EGVIAMLVAKRDLCVLTATENGYGKRTPVAEYTRHGRGTKGMIAIQTSNG
R-LVGACLVEETDEVMLISTGGVLIRTKVQDIRELGRATQGVTLINLD-AS-DTLAGIEKVA--------------------------------------
------------
>tr|A0A0D8M3M4|A0A0D8M3M4_PHOPO DNA gyrase subunit A OS=Photobacterium phosphoreum GN=gyrA PE=3 SV=1
-------HDTILCFSSRGRMYWLKVYQLPLASRTARGKPIVNILP-ERITAIL--PEDKFVFMATADGTVKKTPLTDFSR-RS--AGI---IAVNLREGD
SLIGVDVT---DGDCDIMLFSAFGKVVRFYESGVRGMRAAGVRGIKLA---GVVSLIVPHNKGDILTVTENGYGKRTGLDEYPAKSRATQGVVSI--SNG
S-VVGAVQAE-GDEFMMITNGGTLVRTRVAEVSRVGRNTQGVTLIRTAE-D-EKVVGLQRID--------------------------------------
------------
>tr|F7NWI0|F7NWI0_9GAMM DNA gyrase subunit A OS=Rheinheimera sp. A13L GN=gyrA PE=3 SV=1
-------HDTILCFSNRGRLYWMKVYQLPLASRQARGKPIVNLLP-ERITAIL--PEGKYVFMATANGTVKKTSLTEYSR-RS--NGI---IAVNLNEGD
QLIGVDIT---DGNSQIMLFSDDGKVVRFKEDQVRPMRATGVRGIRLR---NVVSLIVPKSEGAILTVTENGYGKRTALQEYPEKSRATQGVVSI--SNG
L-VVGAVQVN-LDEIMLISDKGTLVRTRVSEVSQVGRNTAGVILIRTIE-G-EKVVGVQRID--------------------------------------
------------
>tr|I9P4V7|I9P4V7_9ALTE DNA gyrase subunit A OS=Alishewanella agri BL06 GN=gyrA PE=3 SV=1
-------HDTILCFSNRGRLYWLKVYQLPLASRTARGKPIVNILP-ERINAIL--PEGKYVFMATANGTVKKTALTEYSR-RS--NGI---IAVNLNEGD
KLIDVGIT---DGSNEIMLFSDDGKVVRFAEDEVRPMRATGVRGIRLR---GVVSLIIPQGEGAILTVTENGYGKRTALTEYPTKSRATQGVVSI--SNG
L-VVGAVQVA-SDEIMMISDKGTLVRTRVREVSEVGRNTQGVILIRTQE-G-EKVSGVERIA--------------------------------------
------------
>tr|A0A0M2V7S8|A0A0M2V7S8_9GAMM DNA gyrase subunit A OS=Arsukibacterium ikkense GN=gyrA PE=3 SV=1
-------HDTILCFSNRGRLYWMKVYQLPLASRTARGKPIVNLLP-ERINAIL--PEGKYVFMATANGTVKKTALTDYSR-RS--NGI---IAVNLNEGD
HLIGVDIT---DGSNEIMLFSDDGKVVRFTEDQVRGMRATGVRGIRLR---GVVSLIIPKGDGAVLTVTENGYGKRTSLTEYPAKSRATQGVVSI--SNG
L-VVGAVQVC-TDEIMMISNRGTLVRTRVKEVSEVGRNTQGVILIRTQD-Q-EKVVGVAKVD--------------------------------------
------------
>tr|A0A0F7M758|A0A0F7M758_9GAMM DNA gyrase subunit A OS=Spongiibacter sp. IMCC21906 GN=gyrA PE=3 SV=1
-------HDTILCFSNIGKVYWLKVYQIPVAGRNSRGRPMVNLLPDERITSILPVREGYFIFMATEQGTVKKTPLEAFSRRRS--VGL---RALELDEGD
VLIGTAIT---NGDDDVVLLSSAGKAARFHEGDVRAMRARGVRGIRMDEQC-VIAMIIPA-GGRVLTVSENGYGKRTPVEEFPCKGRGNRGVIAMTMSNG
D-LVGAVQVFEGDDLMLISDQGTLVRTRTDEVSQLGRNTQGVRVIRLR-ED-EHLVGVQRVA--------------------------------------
------------
>tr|A0YDR7|A0YDR7_9GAMM DNA gyrase subunit A OS=marine gamma proteobacterium HTCC2143 GN=gyrA PE=3 SV=1
-------HDTILCFSNVGKVYWLKVFHIPLASRNARGRPMVNLLPGERITSILPVKEGHYIFMATANGTVKKTELTNFARQRS--VGL---RALELEEGD
VLIGTAVT---NGTCDVMLFSSSGKAVRFNENDVRAMRAKGVRGIRMADQK-MISLLVPK-GGRMLSVSENGYGKRSEFAEFATKGRGNKGMIFMQASNG
E-IIGAVQVFDGDELMMISDQGTMVRTRTDEISVLGRNTQGVRVIRLK-EG-EHVVGVERIE--------------------------------------
------------
>tr|I2JN78|I2JN78_9GAMM DNA gyrase subunit A OS=gamma proteobacterium BDW918 GN=gyrA PE=3 SV=1
-------HTTILCFSNIGKVYWLKVYQIPVAGRNSRGRPMVNLLPGERITSILPVNEGYFIFMATGLGTVKKTPLEAFSRQRS--VGL---RAIELDEGD
VLIGTAIT---NGENDILLLTSAGKAARFAEQDVRAMRARGVRGIRMDEQR-AIAMIIPQ-GGCVLTVSENGYGKRTLVEDFPAKGRGNRGVIAMAMSNG
P-LVGAVQVFEGDDLMLISDQGTLVRTRTDEVSILSRNTQGVRVIRLK-ED-EHLVGVQRVD--------------------------------------
------------
>tr|Q21IS1|Q21IS1_SACD2 DNA gyrase subunit A OS=Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) GN=gyrA PE=3 SV=1
-------HDYLLCFTSVGKVFWLKVYQIPVAGRQSRGRPVVNLLPEERITSILPVRDDHFIFMATADGTVKKTPLSQFARPRS--VGL---RAIDLVEGD
HLVGTAIT---DGTKDIILLTSAGKAARFSEENVRSMRSRGVRGVRMADVS-VIAMVVPE-GGKVLTVSENGFGKRTEVTEYPAKGRGSQGVIAMQMSNG
C-LVGATQVFEGDEIMLISNQGTLVRTRADEVSLSGRNTQGVRLIRVK-EG-EHIVGLERID--------------------------------------
------------
>tr|A0A0A0DSA3|A0A0A0DSA3_9BURK DNA gyrase subunit A OS=Aquabacterium sp. NJ1 GN=gyrA PE=3 SV=1
-------HDYILCFSNRGRVYWLKVWEVPQGSRNSRGRPIVNMFP-EKVNVVLPLT-DHYVFMSTRLGTVKKTPLTDFSNPRK--AGI---IAVGLDEGD
VLVGAALT---DGKHDVMLFSDGGKAVRFDEEDVRPMRARGVRGMMLE--EGVIAMLVAEDTQSVLTATENGYGKRTSIVEYTRHGRGTKGMIAIQQSNG
K-VVAATLVRPEDEIMLITDKGVLVRTRVSEIRELGRATQGVTLISLD-EG-AKLIGLQRIV--------------------------------------
------------
>tr|A0A0Q6T720|A0A0Q6T720_9BURK DNA gyrase subunit A OS=Pelomonas sp. Root1217 GN=ASC95_17790 PE=4 SV=1
-------HDWLLCFSNRGRVYWLKVWEVPQGSRNSRGKPIVNMFP-EKITVVLALT-DHFIFMATAMGTVKKTSLKDFSNPRK--AGI---ISVDLDEGD
HLIGAALT---DGHHDVMLFSDGGKAVRFDEDDVRPMRARGVRGMMLE--PDLIAMLVAEDTQSVLTATENGFGKRTSIVEYTRHGRGTKGMIAIQQSNG
R-VVAATLVRPEDEIMLITDKGVLVRTRVSEIRELGRATQGVTLIALD-DG-SKLSGLQRIV--------------------------------------
------------
>tr|F0NXY6|F0NXY6_WEEVC DNA gyrase subunit A OS=Weeksella virosa (strain ATCC 43766 / DSM 16922 / JCM 21250 / NBRC 16016 / NCTC 11634 / CL345/78) GN=gy
-------HQYMLFFTEKGKCFWLRVFEIPEGSKTSKGRAIQNLINPDKVKAYILTHNNNYVIMVTKNGIIKKTSLEAYSR-RI--NGI---NAITIREDD
TLLEALLT---DGKSQIMIATKYGKAIRFE---VRPMRASGVRGINLGDK-NVIGMIVVSD--TVLVVSEKGYGKRTSIE-YRETNRGGKGVTTLNITTG
K-LIAIESVT-DNDLMIINKSGVAIRTGLSEIRVMGRATQGVKLINLKK-N-DEIAAIAKVE--------------------------------------
------------
>tr|A0A0M4LE38|A0A0M4LE38_9MICC DNA gyrase subunit A OS=Arthrobacter sp. ERGS1:01 GN=gyrA PE=3 SV=1
-------HHWLLFFTNLGRVYRAKAYELAEAGRDAKGQHVANLMAPEKIAQVMDLRSP-YLVLATKSGLVKKTRLEDYDT-RS--AGV---IAINLRDDD
ELVSAQ-----SETDDLLLVSRKGQSIRFTE--LRPMRTSGVTGMKFR-T-DLLAADVVTDDSFVFVVTEGGYAKRTAVDEYRLQGRGGLGIKVAKLVRG
D-LVGALIVKD-DEVLVVMSGGKVVRSNVSEVPA-GRDTMGVIFAKPDK-N-DRIIEVARNS--------------------------------------
------------
>tr|A0A0A1CYU0|A0A0A1CYU0_9MICC DNA gyrase subunit A OS=Arthrobacter sp. PAMC25486 GN=gyrA PE=3 SV=1
-------HHWLLFFTNLGRVYRAKAYELVEAGRDAKGQHVANLLAPEKIAQVMELKSP-YLVLATKNGLVKKTSLEDYDT-RS--AGV---IAINLRDGD
ELVSAQ-----SDADDLLLVSRKGQSIRFTE--LRPMRTSGVTGMKFR-F-DLLSASVVSDESYVFIVTEGGYAKRTAVGEYRLQGRGGLGIKVAKLVRG
D-LIGALIVQE-DEVLVVMGGGKVVRSNVSEVPA-GRDTMGVIFAKPDK-N-DRIIGIARNT--------------------------------------
------------
>tr|G5EP16|G5EP16_9MICC DNA gyrase subunit A OS=Rothia mucilaginosa M508 GN=gyrA PE=3 SV=1
-------HSWILFFTNLGRVYRAKGYELQEAGRDAKGQHIANLLEGEHIAQVMELKAE-YLVLATRGGMVKKSRLSDYDT-RT--AGL---IAINLREGD
EVVSAF-----SDKDDILLVSRNGMSLRFHA--LRPMRTSGVTGMKFR-G-DLISANVVTEGSFVFVVTEGGYAKRTSVDEYRVQGRNGFGIKVAKLVRG
A-LVGGLIVDE-DEVLVVMASGKVVRSNVNEVPA-GRDTMGVIFAKPGK-G-DSIIGVARNQ--------------------------------------
------------
>tr|A0A078MLN9|A0A078MLN9_9MICC DNA gyrase subunit A OS=Arthrobacter sp. 11W110_air GN=gyrA_1 PE=3 SV=1
-------HHWLLFFTNLGRVYRAKAYELAEGGRDAKGQHVANLLAPEHIAQVLDLPAP-YLVLATKRGLVKKTRLADYDT-RS--AGV---IAINLRDED
ELVSAQ-----SETDDLMLVSRKGQSLRFTE--LRPMRTSGVTGMKFR-D-DLLAADVVTEDSFVFTVTEGGYAKKTSVEEYRVQGRGGLGIKVGKFVRG
H-LVGAMVVQG-DEVLVVMQGGKVVRSAVNGVNA-GRDTMGVIFAKPDK-N-DRIIAVARNS--------------------------------------
------------
>tr|U7V512|U7V512_9MICC DNA gyrase subunit A OS=Rothia aeria F0184 GN=gyrA PE=3 SV=1
-------HNWILFFTNMGRVYRTKAYELLEAGRDAKGQHVANLLAPETIAKVMELRAP-YLVLATKGGLVKKTRLSDYDT-RT--AGL---IAINLREGD
EVVSAF-----SPNEDILLVSRQGMSLRFNE--LRPMRTSGVTGMKFR-G-DLISANVVTEDSFVFVVTEGGYAKRTSVNEYRVQGRNGYGIKVAKLVRG
A-LVGALIVDD-DEVLVVMQGGKVVRTGVSEVPA-GRDTMGVIFAKPGK-G-DSIIGVARNQ--------------------------------------
------------
>tr|B2GIG3|B2GIG3_KOCRD DNA gyrase subunit A OS=Kocuria rhizophila (strain ATCC 9341 / DSM 348 / NBRC 103217 / DC2201) GN=gyrA PE=3 SV=1
-------HNWILFFTTLGRVYRVKAYEFVEAGRDAKGQHVANLMEPERIAKVMELHAP-YLVLATRNGLVKKSRLTDYDT-RS--AGV---IAINLRDDD
ELVSAM-----DTDDDIMLISRHGQSLRFTD--LRPMRTSGVTGMKFR-G-DLLSANVVSDDSHVFVVTEGGYAKRTAVQEYRVQGRGGLGIKVAKLARG
G-LVGGLIVGN-DEVLVVMESGKVVRSTVSEVPA-GRDTMGVIFAKPGP-N-DTIVGVARNA--------------------------------------
------------
>tr|A0A0F4P7C7|A0A0F4P7C7_PSEO7 DNA gyrase subunit A OS=Pseudoalteromonas piscicida GN=gyrA PE=3 SV=1
-------HDTILCFSTSGRLYWLKVYQLPLASRAARGKPIVNLLP-ERITTIL--PEDKFIVMATASGIVKKTPLTAYSR-RA--SGI---IAINLNEGD
SLIGANIT---TGENDIMLFTEHGKVVRFNEKALRPMRATGVRGIKMP---DVVSLIVPQGDGAILTVTENGYGKRTPLEEYPAKSRATQGVVSI--TNG
S-VVGAVQVD-NDEIMLISNRGTLVRTRVNEVSTVGRNTQGVILIRTME-E-EKVVGLQRIE--------------------------------------
------------
>tr|A0A0A8HMG3|A0A0A8HMG3_STAHY DNA gyrase subunit A OS=Staphylococcus hyicus GN=gyrA PE=3 SV=1
-------HDHILFFTNKGRVYKLKGYEVPELSRQSKGIPIVNAIESEKISTMIAVKEENFLVFATKKGLIKRSALSNFNR-NK--NGK---IAINFRDDD
ELVAVR-T---DG-KHILIGTSDASLIRFKE--VRAMRASGVRGIRLR---EVVGLGVADEEDEVLVVTEKGYGKRTSVSEYRVSNRGGMGVKTAKLTNG
Q-LISIGTVSD-EDIMVVTNHGVIIRMEVQDISKNGRMAQGVRLIKMAED--QFVSTVAKVK--------------------------------------
------------
>tr|A0A0M2SKB0|A0A0M2SKB0_9STAP DNA gyrase subunit A OS=Salinicoccus sp. SV-16 GN=gyrA PE=3 SV=1
-------HDYIMFFTNKGRVYRLKGYELPELSRQSKGIPIVNMLEKEKISTMIAVKENMFLVFATKNGLVKRSGLENFER-NK--NGK---IAISFRGDD
ELLAVR-T---DG-KEVILGTKYGALIRFPE--IRTMRAAGVKGIRLR---DVVGLDVLAE-QSILVVTDNGYGKLTPEAEYRITNRGGVGVKTANLTVG
E-LIYIASVND-EDLMIVTNHGVIIRLVMEEVSVLGRNTQGVRLIKLSGD--QKVATVAKVK--------------------------------------
------------
>tr|B9E905|B9E905_MACCJ DNA gyrase subunit A OS=Macrococcus caseolyticus (strain JCSC5402) GN=gyrA PE=3 SV=1
-------HDNVLFFTNKGRVYKVKGYEIPELSRQSKGIPIVNVIDKESISTMIAVKEDAYIVFATKHGLIKRSNLSHFSR-NK--NGK---IAINFREED
ELIAVR-T---DG-KQLIIGTKHASLIRFEE--LRPLRAAGVKGISLR---GVIGLDVIESEHEVLVVTENGYGKRTKESEYRISNRGGKGIKTATITNG
N-LVCITTVNN-EDIMIVTDHGVIIRLDVAEFSQNGRSAQGVRLIRLDEG--QFVATVAKVE--------------------------------------
------------
>tr|A0A0C5VQA8|A0A0C5VQA8_9GAMM DNA gyrase subunit A OS=Gynuella sunshinyii YC6258 GN=gyrA PE=3 SV=1
-------HTTIMCFSDRGKVYWLKVWEIPQAGRTAKGRPLINILN-ERVTAVLPIEANKFVFMVTAKGTVKKTALEAFSRQRS--SGL---IALSLDEGD
QLVGVAIT---DGSHEILLLASNGKAVRFSEERVREMRARGVRGIRLGEAE-VISLMIPD-EGTILTVSEKGYGKRTKTQDFPTKGRGTQGVIAMIVNNG
P-LVGAVQIFEGDEIMLISDKGTLVRTRSSEISVLGRNTQGVRLIKVA-ED-ESLVGVERVE--------------------------------------
------------
>tr|B1Y2L5|B1Y2L5_LEPCP DNA gyrase subunit A OS=Leptothrix cholodnii (strain ATCC 51168 / LMG 8142 / SP-6) GN=gyrA PE=3 SV=1
-------HDWMLCFSNRGRVYWLKVWEVPQGGRNSRGKPIVNMFP-EKINVVLPLT-DHYIFMCTARGTVKKTALDDFSNPRK--AGI---IAVDLDEGD
FLIGAALT---DGQHDVMLFSDGGKAVRFDEEDVRPLRARGVRGMALD--EGVIAMLVAEDTQSVLTATENGYGKRTSILEYTRHGRGTKGMIAIQQTNG
K-VVAATLVRPNDEIMLITDRGVLVRTRVAEIRELGRATQGVTLIALD-EG-AKLSGLQRIV--------------------------------------
------------
>tr|A1TSA2|A1TSA2_ACIAC DNA gyrase subunit A OS=Acidovorax citrulli (strain AAC00-1) GN=gyrA PE=3 SV=1
-------HDYILCFSNRGRLYWLKVWEVPAGSRGSRGRPIVNMFP-EKINVVLPLT-DRFVFMATSMGTVKKTALDEFSNPRK--GGI---IAVNLDDGD
YLIGAALT---DGQHDVMLFSDGGKGVRFDENDVRPLRARGVRGMMLE--DGVIAMLVAEDTQSVLTATENGYGKRTSIVEYTRHGRGTKGMIAIQQSNG
K-VVAATLVHAEDEIMLITDKGVLVRTRVAEIRELGRATQGVTLIALD-EG-AKLSGLQRIV--------------------------------------
------------
>tr|A0A0N1LBU0|A0A0N1LBU0_9PROT DNA gyrase subunit A OS=beta proteobacterium AAP99 GN=gyrA PE=3 SV=1
-------HDVILAFSNRGRLYWLKVWEVPEGSRTSRGKPIVNMFP-EKITIVLPLD-DRYVFMTTKLGTVKKTPLSEFSNPRK--AGV---IAVDLDEGD
YLIGAAVT---DGAHDVMLFSDGGKAVRFDENDVRPMRARGVRGMMLE--EGVIAMLVAED-QSVLTATENGFGKRTPITEYTRHGRGTKGMIAIQTSNG
K-VVGATLVHADDEIMLITNTGVLVRTRVAEIREMGRATQGVTLINVD-EG-AKLSGLQRIV--------------------------------------
------------
>tr|I4MNR3|I4MNR3_9BURK DNA gyrase subunit A OS=Hydrogenophaga sp. PBC GN=gyrA PE=3 SV=1
-------HDWILCFSNRGRLYWLKVWEVPSGSRGSRGKPIVNMFP-EKINVVLALT-DHYVFMATAGGTVKKTALDEFSNPRK--AGI---IAVDLDEGD
YLIGAALT---DSHHDVMLFSDGGKAVRFDENDVRPMRARGVRGMMLE--DGVIAMLVAEDTQSVLTATVNGYGKRTPIGEYTRHGRGTKGMIAIQQSNG
K-VVAATLVHTDDQIMLITDKGVLVRTRVAEIREMGRATQGVTLISLD-DG-DELSGLQRIV--------------------------------------
------------
>tr|A0A0Q7A797|A0A0Q7A797_9BURK DNA gyrase subunit A OS=Rhizobacter sp. Root404 GN=ASC76_15165 PE=4 SV=1
-------HDYILCFTNKGRVYWIKVWEVPQGSRNSRGRPIVNMFP-EKVNVVLPLT-DHYVFMATAQGVVKKTSLDEFSNPRK--AGI---IAVDLDEGD
FLIGAALT---DGKHDVMLFSDGGKAVRFDENDVRPMRARGVRGMALD--DGVIAMLVAEDTQSVLTATENGYGKRTSIVEYTRHGRGTKGMIAIQQSNG
K-VVAATLVRADDEIMLITDKGVLVRTRVAEIREMGRATQGVTLIALD-QG-AQLIGLQRIV--------------------------------------
------------
>tr|F3KRN8|F3KRN8_9BURK DNA gyrase subunit A OS=Hylemonella gracilis ATCC 19624 GN=gyrA PE=3 SV=1
-------HDYILCFSNRGRLYWLKVWEVPEGSRNSRGRPIVNMFP-EKITVVLPLT-DHYVFMATRMGTVKKTSLDEFNNPRK--AGI---IAVDLDAGD
FLIGAALT---DGRHDVMLFSDGGKAVRFDENDVRPMRARGVRGMMLD--DGVIAMLVAQDRTSVLTATENGYGKRTPIAEYTRHGRGTKGMIAIQQSNG
K-VVAATLVHTDDEIMLITDKGVLVRTRVSEIREMGRATQGVTLIALD-DG-TQLSGLQRIV--------------------------------------
------------
>tr|J3VU17|J3VU17_9ENTR DNA gyrase subunit A OS=secondary endosymbiont of Heteropsylla cubana GN=gyrA PE=3 SV=1
-------HETILLFSSRGRIYWMKVYQLPEASRGARGRPIINLLP-ERITAIL--PKGSHVFMATSSGTVKKTPLVEFSR-RS--AGI---IAMNLDVGD
ELIGIDLT---DGNDEVMLFSAYGKVVRFPENQVRSMRARGVRGINLA---GVVSLIVPRGNDSILTVTQYGYGKRTLQKEYPTKSRSTQGVISI--NNG
K-VVCALEVN-SDQIMLITDAGTLVRTRVSEISIIGRNTHGVTLIRTAQ-E-EKVVGLQRVA--------------------------------------
------------
>tr|C5QP83|C5QP83_9STAP DNA gyrase subunit A OS=Staphylococcus caprae M23864:W1 GN=gyrA PE=3 SV=1
-------HDNVLFFTNKGRVYKLKGYEVPELSRQSKGIPIVNAIENETISTMIAVREDDYLVFATKRGIVKRSALSNFSR-NK--NGK---IAISFKEDD
ELIAVR-T---TG-EDILIGTSHASLIRFPE--LRPLRAAGVKGITLR---GVVGLDVAHAEDEVLVVTENGYGKRTPVSEYRLSNRGGKGIKTATITNG
N-IVCITTVTE-EDLMVVTNAGVIIRLDVEDISQNGRAAQGVRLMKLGEG--QFVSTVAKVK--------------------------------------
------------
>tr|A0A0B3B2Z2|A0A0B3B2Z2_9ARCH DNA gyrase subunit A OS=archaeon GW2011_AR13 GN=gyrA PE=3 SV=1
-------HDNLMFFTTRGRVLWLKAHDIPAAERYSKGKAIVNLLND-RVTNVISVK-NEDLFMATQKGLVKKIALSHFSKPRA--SGV---KAINLPLDN
SDVLIGVV---KKGQEVLLATKKGQAIRFNS--VRAMRSYGVTGIKLG---EVVSLEVLDT-AAILTISENGYGKRTAIEDYRKTARAGKGVINL--TTG
K-IVTTVAVNDEDTIIITTAKGIVIRTTLNNIRVMGRATQGVRIVKLAE-G-DKVTDLIRVL--------------------------------------
------------
>tr|A0A033UT10|A0A033UT10_STAAU DNA gyrase subunit A OS=Staphylococcus aureus C0673 GN=gyrA PE=3 SV=1
-------HDNVLFFTNKGRVYKLKGYEIPEMSRQSKGLPIVNALEKEMISTMIAVKEEDYLVFATKHGTVKRSKLSNFSR-NK--NGK---IAINFKEGD
ELIAVR-T---DG-KEIIIGTKHASLIRFDE--LRPLRAAGVKGITLR---DVIGLDVTDEQDEILIVTEKGYGKRTSADQYRISNRGGKGIKTATLTNG
N-LVCITTVND-EDLMIVTNSGVIIRLHVADISQNGRSAQGVRLIRLGEN--QHVATVAKVE--------------------------------------
------------
>tr|A0A0F5AU90|A0A0F5AU90_9GAMM DNA gyrase subunit A OS=Salinivibrio sp. KP-1 GN=gyrA PE=3 SV=1
-------HDTILCFSTRGRMYWLKVYQLPHASRNARGKPIVNLLP-ERITAIL--PEDKYVFMATAHGTVKKTPLTDFSR-RS--AGI---IAVNLREGD
SLIGAQLT---DDSSEVMLFSQFGKVVRFLASTVRAMRAAGVRGIQLA---NVVSLIVPQENAEILTVTENGFGKRTALAEYPTKSRATKGVVSI--SNG
D-VVSAIQVC-GDELMMITNAGTLVRTRAEEVSQVGRNTQGVRLIRVSD-D-EKVVGLQRIE--------------------------------------
------------
>tr|A0Y646|A0Y646_9GAMM DNA gyrase subunit A OS=Alteromonadales bacterium TW-7 GN=gyrA PE=3 SV=1
-------HDTILCFSTAGRLYWLKVYQLPLASRAARGKPIVNLLP-ERITAIL--PEDKYIFMATAFGTVKKTPLTAYSR-RA--SGI---IAVNLNEGD
SLIGVDIT---DGTNEIMLFTDAGKVVRFKEAGVRPMRATGVRGIKMT---EVVSLIVPKTDGAILTVTENGYGKRTQLEDYPSKSRATQGVVSI--SNG
A-VVGAVQVD-NDEIMLISNRGTLVRTRVNEVSTVGRNTQGVILIRTID-E-EQVVGLQRIE--------------------------------------
------------
>tr|U2EL95|U2EL95_9GAMM DNA gyrase subunit A OS=Salinisphaera shabanensis E1L3A GN=gyrA PE=3 SV=1
-------HDTLLCFSSAGKAYWLKVYELPSAGRGARGKPIVNLLP-ERISQVLPIKTSQNVFFATRNGTVKKTALEQFSRPRS--NGI---IAIDLRDDD
ALVGVDLT---GGDDELMLFSSGGKVIRFAERDVREMRAAGVRGIRLPEEADVIALIV-IRDGDILTVTEQGYGKRTPVGDYPLRGRGGQGVLSLKQSSG
A-VVGATQVLEDDEIMLISNMGTLIRTAVAEISVLGRNTQGVRIIRVA-DD-QHLVGVDRII--------------------------------------
------------
>tr|R4V4A2|R4V4A2_9GAMM DNA gyrase subunit A OS=Spiribacter salinus M19-40 GN=gyrA PE=3 SV=1
-------HDTLLCFSSHGKCYWLKVYELPHGSRGSKGKPIVNLLP-ERINAVLPVSGDYHVFMATQQGTVKKTPLSHFSRPRS--SGI---IAVHLADGD
RLVNVGMT---DGNSDIMLLTSAGKAIRFEESKVRAMRAAGVRGVRLAPQT-VIECLILG-EGHVLTVTENGFGKVTPVADYPLRGRGGMGVIGIQTSNG
A-VVGAAQVSEDDEVMLISNGGTLVRTRAAEISVLSRNTQGVKLISLG-RG-EHLVGLARIE--------------------------------------
------------
>tr|U5T5V6|U5T5V6_9GAMM DNA gyrase subunit A OS=Spiribacter sp. UAH-SP71 GN=gyrA PE=3 SV=1
-------HDTLLCFSSRGKCYWLKVYELPHGSRGARGKPIVNLLP-ERINAVLPISADRFVFMATRQGTVKKTPLVDFSRPRA--NGI---IAVNLGDDD
TLVNVGVT---DGNREIMLLTDAGKAIRFNESEVRAMRATGVRGVRLGTQV-VIQSLILE-EGDVLTVTGNGYGKLTPVADYPLRGRGGMGVIGIQTSNG
A-VVGALQVNQDDEIMLITNGGTLVRTRAAEVSVLSRNTQGVKLIALS-ED-ETLVGLAKVE--------------------------------------
------------
>tr|A0A084IHP5|A0A084IHP5_9GAMM DNA gyrase subunit A OS=Salinisphaera hydrothermalis C41B8 GN=gyrA PE=3 SV=1
-------HDTLLCFSSYGKAYWLKVYELPSAGRGARGKPIVNLLP-ERISEVLPIKTDENVFFATRNGTVKKTALEQFSRPRT--NGI---IAIDLRDDD
ALVGVDRT---AGNDTIMLFSSAGKVIRFAEADVRQMRAAGVRGIRLPEDDTVIGLIVVR-EGEILTVTEHGYGKRTPVDDYPLRGRGGQGVLALKQSTG
A-VVGATQVSEDDEIMLISNMGTLIRTAVSEVSVLGRNTQGVRIIRVG-DG-QRLVGVDRIA--------------------------------------
------------
>tr|B5JSE9|B5JSE9_9GAMM DNA gyrase subunit A OS=gamma proteobacterium HTCC5015 GN=gyrA PE=3 SV=1
-------HDTLLCFSSYGKVYWKKVYELPIGSRNARGKPIVNLLP-ERISAVLPVRDDEFVFMATANGTVKRTALSNFSRPRS--NGI---IALDIRDGD
RLVGVART---DGQRDIMLFADSGKAIRFNEQDVRPMRAAGVRGIRLSDQT-MVGLIIVE-DGDILTATVNGYGKRTAIEDYPTQGRGGSGVLSIKTSNG
G-VVGAVQVATEDEIMLISNGGVLVRTAVEDISVMSRNTQGVRLIRLD-DK-EQLVELERIP--------------------------------------
------------
>tr|I3CH81|I3CH81_9GAMM DNA gyrase subunit A OS=Beggiatoa alba B18LD GN=gyrA PE=3 SV=1
-------HDTILCFTSAGKVYWLKVYELPQAGRNARGKPIVNLLP-ERVNAVLPVRENRYIFMATVSGTVKKTPLTEFSRPRT--NGI---IALALDEGD
QLVNVAIT---DGQQDVMLFSNHGKAVRFTEDAVRSVRARGVRGILLEKDK-VISLIITE-GGTILTATENGYGKRTPIDDYPTKGRGTKGVISIKTSNG
L-VVGAVQVQDNDDLMLISNRGTLVRTPVAGISVVSRNTQGVGLIRLV-DE-ELLVGVEKIM--------------------------------------
------------
>tr|A0A0G3G1B7|A0A0G3G1B7_9GAMM DNA gyrase subunit A OS=Thioalkalivibrio versutus GN=gyrA PE=3 SV=1
-------HDTILCFSSRGRVYWLKVYELPQGSRAARGKPIVNLLP-ERISTILPVRPDHYVFMVTAQGTVKKTPLTDFSRRRA--SGI---IAVDLREGD
HLVDVSLT---DGTLDVMLVTTAGKAVRFHESDVRAMRACGVRGVRMEDQR-VIALLNVD-EGSALLATEHGYGKRTRFDEFPVHRRGGQGVIAIQTENG
L-LVGAARVLDDDEVMLITNGGTLVRTPIDQIPLIGRNTQGVRLIRLD-ED-ENLVELARVA--------------------------------------
------------
>tr|A0A0R2FAC6|A0A0R2FAC6_9LACO DNA gyrase subunit alpha OS=Lactobacillus camelliae DSM 22697 = JCM 13995 GN=FC75_GL000823 PE=4 SV=1
-------HDMLLFFTNTGKVYRMKGYEVPEYSRTAKGIPIINLLGDEKIQTVLNVKSDDYLFFVTRNGVVKRTPTREFYN-RK--NGL---IALNMKDGD
ELSNVI-T---TG-NTIFIGTHLGYSVTFKE--VRSMRATGVRGVRLR---GVVGSDILKPDSEVFVISEKGYGKRTAASEYPIKGRGGKGIKTANITNG
P-LAGVTTVDT-EDIMVITDAGVMIRFNIDTVSQTGRSTLGVRLIKVDDG--AKVATMAKLA--------------------------------------
------------
>tr|A0A0R1ZKR0|A0A0R1ZKR0_9LACO DNA gyrase subunit alpha OS=Lactobacillus sharpeae JCM 1186 = DSM 20505 GN=FC18_GL001193 PE=4 SV=1
-------HDTLLFFTNKGKVFRSKGYEIPEYGRTAKGIPIVNLLGSEKIQAVINVPNDDFLFFITQNGTVKRTAVSEFAN-RS--NGL---IALSLRDDD
ELSNVL-T---DG-STIIIGSKSGYSVTFKE--VRSMRAAGVRGMNLR---GVIGSDVLRPDAHVFVISEQGYGKQTKASEYPIKGRGGKGIKTVNVTNG
E-LAGLTTIND-EDILVVTDAGVMIRFHAKDVSETGRSAIGVRLIRVDDG--AKVATMAKVD--------------------------------------
------------
>tr|A0A0R1QQ17|A0A0R1QQ17_9LACO DNA gyrase subunit alpha OS=Lactobacillus manihotivorans DSM 13343 = JCM 12514 GN=FD01_GL001389 PE=4 SV=1
-------HDVLLFFTNSGKVYRAKGYEIPEYGRTAKGIPIINLLGDEKIQTVINVNRADYLFFVTKHGIVKRTPVAEFLN-RK--NGL---IALNMKPDD
ELSRVI-T---TG-ATMLIGTHNGYSVTFKE--VRSMRATGVRGIRLR---DVVGADVLTPDSEVFVVSEKGYGKRTAASEYPIKGRGGKGIKTANVTNG
P-LAIVTTVND-EDIMAVTDAGVMIRFNIDTVSQTGRATLGVRLMRVDAG--TKVVTVAKLA--------------------------------------
------------
>tr|A0A0R1K3M4|A0A0R1K3M4_9LACO DNA gyrase subunit A OS=Lactobacillus nasuensis JCM 17158 GN=FD02_GL001725 PE=4 SV=1
-------HDVLLFFTNNGKVYRSKGYEIPEYGRSAKGIPIINLLGAEKVQTVINVKDNKFLFFVTTGGVVKRTPVAEFLN-RK--NGL---IALKMREGD
TLNNVI-T---TG-DTMFIGTHLGYSVTFKE--VRVMRATGVRGVRLR---GVVGSDILHDTDEVFVVSEKGYGKRTPASEYPIKGRGGKGIKTANITNG
P-LAGVTTVAT-EDILAMTDSGVMIRFNIDTVSQTGRATLGVRLMRVDDG--AKVVSMAKVD--------------------------------------
------------
>tr|A0A0R2C5J4|A0A0R2C5J4_9LACO DNA gyrase, A subunit OS=Lactobacillus thailandensis DSM 22698 = JCM 13996 GN=FD19_GL001287 PE=4 SV=1
-------HDVLLFFTDAGKVYRMKGYEIPEYGRTAKGLPIINLLGNEKIQAVITVPGEHYLFFVTKQGVVKRTAVAEFGN-RR--NGL---IAINLKDDD
QLTNVM-T---EG-DNILIGTHNGYSVTFNE--VRGMRAAGVRGIRLR---GVVGSDIMRPGSDVFIISEKGYGKRTPVSEYPVKGRGGKGIKTANVTNG
P-LAGVTTVDT-EDILVVTDAGVMIRFRSGSVSQTGRATLGVRLIRVDDD--TKVASMAKVE--------------------------------------
------------
>tr|A0A0R2FZS3|A0A0R2FZS3_9LACO DNA gyrase subunit A OS=Lactobacillus selangorensis GN=IV38_GL000820 PE=4 SV=1
-------HHVLLFFTNTGKIYRMKGYEIPEYSRTAKGIPVINLLGNEKIQTVISVSDKNDLFFVTKNGTVKRTAVSEFAN-RK--NGL---RALMLKDDD
ELTNVL-T---DG-QNIIIGTHLGYAVSFKE--VRQMRATGVRGIRLR---NVVGSDILHPNADVFVISEKGYGKRTPVADYPIKGRGGKGIKTTNITNG
P-LAGLTTVNS-EDILVMTNTGVMIRFSSSDVSQTGRSTLGVRLIRLDDN--AIVVSMARVL--------------------------------------
------------
>tr|A0A0Q9YJJ2|A0A0Q9YJJ2_9COXI DNA gyrase subunit A OS=Coxiellaceae bacterium CC99 GN=gyrA PE=4 SV=1
-------HDTILCFSDKGKVYWLKVYDLPLGNRQSKGKPIVNFLP-EKISAILPIKEGSYVFMATRMGTVKKVDLLDFSRPRA--SGI---IAVDLEEED
SLVGAELT---DGARDVMLFTNAGKAVRFHEDTVRAMRAKGVRGIRLQE--QVVSMIVLGEYQSLLIATENGFGKRTLVEEFPVKGRGGQGVISIQTTNG
Q-GVGARGIRDKDEAMLISDGGILVRLRTDEISLVGRNTQGVTLINLG-EG-EKLIGLERVE--------------------------------------
------------
>tr|A0A0Q9Z0P8|A0A0Q9Z0P8_9COXI DNA gyrase subunit A OS=Coxiellaceae bacterium HT99 GN=gyrA PE=4 SV=1
-------HDTILCFSSKGKVYWLKVYQLPLGSRNSLGKPIINLIPEERISAILPLRDTHCVVMATAQGVIKKVNISEFSRPRS--SGI---IAVDLDEND
ELVGAETT---DGDRDIMLFTNSGKAVRFHENTVRCMRARGVRGVKLQEQR-VISLIVVKSDCTILIATENGYGKRTPVSDFPVKGRGGQGVIAIQTTNG
N-VIGAVQVENNDEIMLITDGGTLVRTRVDEISVVGRNTQGVTLIQLS-NE-EKLVGLQRIL--------------------------------------
------------
>tr|A0A0F7KHV4|A0A0F7KHV4_9PROT DNA gyrase subunit A OS=Nitrosomonas communis GN=gyrA PE=3 SV=1
-------HDYILCFSSLGRVYWVKVYNVPQGSRSSRGKPINNLLQ-EKINAVLPVK-NRYIFMATAFGTVKKTPLSEFSRPRN--NGI---IAIDLDKDD
YLIGVALT---EGKHDVMLFSDNGKAMRFDE-DVRAMRARGVRGMKLG--AGVISMLVAENELAVLTATENGYGKRTPISEYTRHNRGTQGMIAINTGNG
K-VVAAQLVKSDDEIMLITTGGVLIRTRVNEIREMGRATQGVTLINLD-QG-EKLAGLERVI--------------------------------------
------------
>tr|Q82XE2|Q82XE2_NITEU DNA gyrase subunit A OS=Nitrosomonas europaea (strain ATCC 19718 / NBRC 14298) GN=gyrA PE=3 SV=1
-------HDFILCFSSLGRVYWIKVYNVPQGSRTSRGRPVNNLVP-EKINAVLPVK-TRYVFMSTAGGTVKKTPLSEFSRPRT--NGI---IAIDLDEGD
YLIGVALT---EGKHDVMLFSDAGKAMRFDE-DVRPTRARGVRGMKLG--AGVISLLVADNNMAVLTATENGYGKRTPITEYTRHNRGTQGMIAINTNNG
K-VVAAQLVESSDEIMLITTGGVMIRTRVSEIREMGRATQGVTLINLD-AG-EKLAGLERIV--------------------------------------
------------
>tr|Q3SK89|Q3SK89_THIDA DNA gyrase subunit A OS=Thiobacillus denitrificans (strain ATCC 25259) GN=gyrA PE=3 SV=1
-------HDYILCFSNRGRLYWLKVYNVPQGGRAARGKPIVNLLP-EKISALLPVK-EHYVFMATANGIVKKTPLSEFSRPRT--AGI---IAVGLDDGD
VLCGASIT---DGRHDVMLFSDSGKAVRFDE-DVRPMRARGVIGMKLA--KGLISLLVAEDNDFVLTATENGYGKRTPIAEYTRHARATQGMIAIQTSNG
K-VVAANLVKADDEIMLITTGGVLIRTRVKEIRAMSRATQGVTLINLD-KG-EKLISLEKVA--------------------------------------
------------
>tr|E6QX62|E6QX62_9ZZZZ DNA gyrase subunit A OS=mine drainage metagenome GN=gyrA PE=3 SV=1
-------HDYMLCFSNLGRVYWLKVYEVPQGSRTSRGKPIVNLLP-EKINAILPVK-SRYVFMATALGVVKKTQLSDFSNPRR--AGI---IAVDLDEGD
YLIGVSLT---DGQHDVMLFSNSGKAVRFDE-DVRSMRARGVRGMKLA--KDVISLLVAENQQSVLTVTENGYGKRTNIAEYTRHARGTQGIIAIQTTNG
G-VVAATLVEADDEIMLITDGGILIRTRIREVREMGRATQGVTLIHLD-SG-QKLIGVERVL--------------------------------------
------------
>tr|M5DKJ9|M5DKJ9_9PROT DNA gyrase subunit A OS=Nitrosospira lacus GN=gyrA PE=3 SV=1
-------HDYILCFSSRGRVYWIKVYAVPQGGRASRGKPIVNLVQ-EKINAILPVK-NRYIFMATSFGTVKKTPLSEFSRPRA--SGI---IAVGLDEDD
YLIGVALT---EGKHDVMLFSDGGKAVRFDE-DVRAMRARGVRGMKLG--KGVISLLVAESEQAVLTATENGYGKRTPISEYTRHGRGSQGMIAIKTSNG
K-VVAARLVRQDDEIMLITTGGVLIRTRVKEVREMSRATQGVTLINLD-DG-EKLAGLERVV--------------------------------------
------------
>tr|F8GHP2|F8GHP2_NITSI DNA gyrase subunit A OS=Nitrosomonas sp. (strain Is79A3) GN=gyrA PE=3 SV=1
-------HDYILCFSSLGRVYWIKVYEVPQGGRLSRGKPIINLVQ-EKINAILPVK-TRYIFMATSFGTVKKTPLSEFSRPRN--NGI---IAIGLDEGD
YLIGVELT---EGKHDVMLFSDNGKAMRFSE-DVRPMRARGVRGMKLG--SGVISLLVAENELSVLTATENGYGKRTPISEYTRHNRGTQGMIAIKTSNG
K-VVTAKLVKPDDEIMLITSGGVLIRTRVNEVREMSRATQGVTLINLD-AG-EKLAGLERVV--------------------------------------
------------
>tr|A0A0R0LHU2|A0A0R0LHU2_9PROT DNA gyrase subunit A OS=Ferrovum sp. JA12 GN=gyrA PE=4 SV=1
-------HDHVLCFTSLGRVHWLRVFNVPVGSRTSRGKPVNNLLH-EKINALLPVK-EHFVLMATAFGTVKKTPLTDFSRPRS--AGI---IAVDLDEND
YLVGAAIT---NGEHDVMLFSDDGKAIRFNE-DVRAMRARGVRGMRLS--PNVISMLVAKNEQTVLTATANGFGKRTPIAEFTRHGRGGQGMISIHTSNG
S-VVSAALVNTSDELMLITSGGVLIRTRVEEIREMSRATQGVTLIALD-KG-ETLVSLSPID--------------------------------------
------------
>tr|R4YLU8|R4YLU8_OLEAN DNA gyrase subunit A OS=Oleispira antarctica RB-8 GN=gyrA PE=3 SV=1
-------HDTVLCFTDAGKVFWLKVYDIPQASRNAKGRPMVNVVNGERITAILPLPGEEFIFMATSMGTVKKTSLEHFQRPRS--SGL---IACELDEGD
HLIGVAIT---DGTKDILLLTDAGKANRFNESAVRAMRARGVRGIRIQEQK-VISLVIPEEGGTLLTASDRGYGKRTLISEFPTKGRGTQGVKAMVVNNG
I-IVGAVQVFENDEVMLISDKGTLVRTSADSVSCLGRNTQGVRLIKVA-EK-ERLIGVERVC--------------------------------------
------------
>tr|Q1N5G2|Q1N5G2_9GAMM DNA gyrase subunit A OS=Bermanella marisrubri GN=gyrA PE=3 SV=1
-------HDTILCFSNAGKVYWLKVYDIPVASRQSRGRPIVNLLP-EWITTILPVREGHYIFMATSKGTVKKTDLTAFSRPRS--SGL---IALELEEGD
TLMGAEIT---DGNQDVLLMSDVGKAVRFAESNVRAMRARGVRGIKMQDQK-VVSLMIPK-GATVLTASEHGYGKRTDVDEFPTKGRGTQGVIGMVTNNG
K-LVGAVQVFDGNEIMLITNQGTLVRTRVSEVSTLGRNTQGVTLIRVQ-EG-ERLVGIAPIM--------------------------------------
------------
>tr|A4BJH9|A4BJH9_9GAMM DNA gyrase subunit A OS=Reinekea blandensis MED297 GN=gyrA PE=3 SV=1
-------HDTILCFSTFGKVYWLRVFEIPQASRAARGRPMVNLLP-ERVTAILPIRPDYFIFMATASGTVKKTSLDAFSRPRS--SGL---IALSLDEGD
HLVGVACT---DGEREVMLLSDAGKVVRFKEEHVRPMRARGVRGISLEDQS-VISLIVPQ-EGFVLTASERGYGKRTVMTEFPTKGRGTKGVIAMVSNNG
K-LVGAKQVFNGDEVMLISDQGTLVRTRVDEISSLGRNTQGVKLIRVA-DD-EKLVSIERIE--------------------------------------
------------
>tr|M5DTZ4|M5DTZ4_9GAMM DNA gyrase subunit A OS=Thalassolituus oleivorans MIL-1 GN=gyrA PE=3 SV=1
-------HDTVLCFTDAGKVYWLTVYDIPQASRNAKGRPIVNVLNEERITAILPVPAERYVFMVTARGTVKKTTLDQFSRPRS--SGL---IACELDEGD
HLVGVAIT---DGTQEILMLSNAGKAVRFKETDVRAMRARGVRGIRLGEQR-VISLIIPE-NGAILTASERGYGKRTLVTEFPTKGRGTQGVIAMVTSNG
A-LVGAVQVFEGDEVMLVSDQGTLVRTRTSEVSLLGRNTQGVTLIRIA-DK-EKLVGVERIC--------------------------------------
------------
>tr|B4D634|B4D634_9BACT DNA gyrase subunit A OS=Chthoniobacter flavus Ellin428 GN=gyrA PE=3 SV=1
-------HDYLMFFTVEGRCYVERVFEIPEGTRTSKGRSIANVLEQEKIAATIRIQ--LHIVFATRSGIVKKSNLNEFKNIRK--GGI---IAIQIETGD
RLIDCKLT---TGLDEIVLITHEGMSIRFNE--LRDQRTVGVWGIRPD---YVVAAALVNKEAMLLVAGENGIGKRTGFDEYRIQSRGGKGIITM--TTG
S-VAGALTVVETDELMLITNKGKMVRTRVAEIRETGRNAQGVKLIDLRE-N-EILQGIAPVV--------------------------------------
------------
>tr|Q1YRS3|Q1YRS3_9GAMM DNA gyrase subunit A OS=gamma proteobacterium HTCC2207 GN=gyrA PE=3 SV=1
-------HATILCFTNLGKVYWLKVYQIPVAGRNSRGRPVINLLPGERISSILPVEADKFVIMATANGTVKKTSLEQYSRPRS--VGL---RAVDLVEGD
HLVGTAII---DDDSDVMLLSSEGKAVRFASTDARSMRSKGVRGMRLPEHE-VISMVVPE-DGFLLTVCENGYGKRTKVDEFPTKGRGGKGMIAIQASNG
P-LVGATQLFAGDEIMLISDQGTMVRTRGDEVSVVGRNTQGVRIIRLK-DS-ENLVRLARIA--------------------------------------
------------
>tr|F3KZY9|F3KZY9_9GAMM DNA gyrase subunit A OS=gamma proteobacterium IMCC3088 GN=gyrA PE=3 SV=1
-------HSTILCFTNLGKVYWLKVYQIPVAGRQSRGRPMVNLLP-ERVTSILPVAEDHYIFMATAKGIVKKTALTDFSRPRS--VGL---RALELAEDD
VLVGTAIT---HGESDVMLMSSAGKAVRFAEQDVRPMRARGVRGIRMGDDE-MIALIIPQ-GSYVLTASANGYGKKTMASEFPRKGRGTKGVIAMVTNNG
P-LVGAVQVGEADELMLISNQGTMVRTRVSEISTLGRNTQGVRVIRLK-EG-EELVRITQIE--------------------------------------
------------
>tr|A0A095X374|A0A095X374_9GAMM DNA gyrase subunit A OS=Pseudohaliea rubra DSM 19751 GN=gyrA PE=3 SV=1
-------HATILCFSSLGKVYWLKVYQIPLAGRGSRGRPLVNLLP-ERVTSILPVEPGHFIFMATAGGTVKKTPLTNFARPRS--VGL---RALELDEGD
VLIGTAIT---DGNCDVMLFSSGGKVARFSEDDVRPMRARGVRGIRLAGQQ-MISLVIPR-DGRILTVSEKGYGKRTDVVEFPTKGRGNMGVIAMAQSNG
E-LVGAVQVFDGDELMLISNLGTLVRTRADEVSMLSRNTQGVRIVRCK-DG-EQLVRVAQID--------------------------------------
------------
>tr|B7RYF2|B7RYF2_9GAMM DNA gyrase subunit A OS=marine gamma proteobacterium HTCC2148 GN=gyrA PE=3 SV=1
-------HATILCFSNLGKVYWLKVYQIPLAGRNSRGRPMINLLP-ERVTSILPVEEGHYIFMATASGTVKKTALINFARQRS--VGL---RALELEEGD
VLVGTAVT---TGDCDVMLLSSEGKAVRFKEGDVRAMRARGVRGIKLGDHE-MISLIIPR-GGRVLTVSENGYGKRTEMSEFPTKGRGTKGVIAMQTSNG
T-LVGAVQVFDGDQLMLISNQGTLVRTRADEISVLGRNTQGVRVIRTK-TD-ESLVSVERIE--------------------------------------
------------
>tr|S8GXQ4|S8GXQ4_9BACT DNA gyrase subunit A OS=Bacteroidetes bacterium oral taxon 272 str. F0290 GN=gyrA PE=3 SV=1
-------HNTMMFFTKKGRCFWLKVYEIPEGTKTSKGRAIQNVLNADAVTAYIRIKHSHCLMFCTRQGIVKKTLLEQYSR-RT--NGI---NAINILPGD
EVIDVCLT---LREDEIIIANKNGRAIRFN---VRMMRATGVHGMRLD-A-DVVGMVRIKDQETIMVVSEQGYGKRSEIA-YRLTNRGGKGVKTLNITTG
K-LIAIKAVT-DHDLMIINKSGITIRLKLADVRIMGRATQGVRLINLEKRN-DEIASVCKVN--------------------------------------
------------
>tr|F3LUC8|F3LUC8_9BURK DNA gyrase subunit A OS=Rubrivivax benzoatilyticus JA2 = ATCC BAA-35 GN=gyrA PE=3 SV=1
-------HDWILCFSDRGRVYWLKVWEVPQGSRNSRGKPIVNMFP-EKITVVLPLT-DHYVFMSTALGTVKKTPLDEFSNPRK--AGI---IAVGLDEGD
YLIGAALT---DGRHDVMLFSDGGKAVRFDEDDVRPMRARGVRGMALE--PGVIAMLVSDRRVSVLTATENGFGKRTPIGEYTRHGRGTKGMIAIQQSNG
K-VVAATLVRETDEIMLITDRGVLVRTRVAEIREMGRATQGVTLIALD-DG-AKLSGLQRIV--------------------------------------
------------
>tr|A0A0N1AEW5|A0A0N1AEW5_9PROT DNA gyrase subunit A OS=beta proteobacterium AAP65 GN=gyrA PE=3 SV=1
-------HDWILCFSDRGRVYWLKVWEVPQGSRASRGKPIVNMFP-EKVTVVLPLT-DHFVFMSTALGTVKKTSLDEFSNPRK--AGI---IAVDLDEGD
HLIGAALT---DGQHDVMLFSDGGKAVRFAEDEVRPLRARGVRGMALE--DGVIAMLVAEDTQSVLTATENGYGKRTSIVEYTRHGRGTKGMIAIQQSNG
K-VVAATLVRQPDEIMLITDKGVLVRTRVSEIRELGRATQGVTLIALD-NG-AKLSGLQRIV--------------------------------------
------------
>tr|I0HNZ6|I0HNZ6_RUBGI DNA gyrase subunit A OS=Rubrivivax gelatinosus (strain NBRC 100245 / IL144) GN=gyrA PE=3 SV=1
-------HDWILCFSDRGRVYWLKVWEVPQGSRNSRGKPIVNMFP-EKITVVLPLT-DHYVFMVTAFGTVKKTPLDDFSNPRK--AGI---IAVGLDDGD
YLIGAALT---DGHHDVMLFSDGGKAVRFNEDGVRPMRAGGVKGMELE--PGVIALLVAEDTQSVLTATENGYGKRTPIAEYTRHRRGGKGMISMLQSNG
K-VVAATLARDTDEIMLITDRGVLVRTRVAEIREMGRATQGVTLISLD-DG-TRLSGLQRIV--------------------------------------
------------
>tr|A0A059KP78|A0A059KP78_9BURK DNA gyrase subunit A OS=Sphaerotilus natans subsp. natans DSM 6575 GN=gyrA PE=3 SV=1
-------HDWMLCFSDRGRVYWLKVWEVPQGGRASRGKPIVNMFP-EKITVVLPLT-DHYIFMSTALGTVKKTALDEFSNPRK--AGI---IAVDLDEGD
HLIGAALT---DGEHDVMLFSDGGKAVRFHEGDVRPMRARGVRGMSLE--DGVIAMLVAEDSQSVLTATENGYGKRTAIAEHTRHGRGTKGMIAIQQSNG
R-VVAATLVRAEDEIMLITDRGVLVRTRVSEIREMGRATQGVTLIALD-EG-SQLSGLQRIV--------------------------------------
------------
>tr|U5N9U3|U5N9U3_9BURK DNA gyrase subunit A OS=Candidatus Symbiobacter mobilis CR GN=gyrA PE=3 SV=1
-------HDYILCFSNRGRLYWIKVWEVPQGSRGSRGRPIVNMFP-EKITVVLPLT-DRYVFMATSMGTVKKTALDEFRNPRK--AGI---IAVDLDEGD
YLIGAALT---DGNHDVMLFSDGGKAVRFDEGDVRPLRARGVRGMMLE--EGVIAMLVAEDNQSVLTATQNGYGKRTNIAEYTRHGRGTKGMIAIQQSNG
K-VVAATLVHPGDEIMLMTDRGVVVRTRVNEIPELGRATQGVTLIGLD-EG-SQLIGLERIA--------------------------------------
------------
>tr|A1VR14|A1VR14_POLNA DNA gyrase subunit A OS=Polaromonas naphthalenivorans (strain CJ2) GN=gyrA PE=3 SV=1
-------HDYILCFSDRGRLYWLKVWEVPAGSRGSRGRPIVNMFP-EKITVVLALT-DQYVFMATSMGTVKKTPLDDFNNPRK--GGI---IAVALDEGD
YLIGAALT---DGKHDVMLFSDGGKAVRFDENDVRPMRARGVRGMNLE--EGVIAMLVAEDEQSVLTATQMGFGKRTSISEYTRHGRGTKGMIAIQQSNG
K-VVAATLVHADDEIMLITDRGVLVRTRVSEIREMGRATQGVTLIGLD-EG-SQLSGLQRIV--------------------------------------
------------
>tr|A0A038JN26|A0A038JN26_9BORD DNA gyrase subunit A OS=Bordetella holmesii CDC-H809-BH GN=gyrA PE=3 SV=1
-------HDYLLCFSNRGRVYWLKVWEVPQGTRNSRGKPIVNMFP-EKITVVLPVK-DHYVFMATSRGTVKKTALSDFSNPRK--AGI---IAVDLDDGD
YLIGADVT---DGKHDVMLFSDAGKAVRFDENDVRPMRARGVRGMMLE--DSVIALLVAGDSQSVLTATENGYGKRTSIAEYTRHGRGTKGMIAIQTSNG
K-VVGAVLVNPSDEIMLITTGGVLVRTRVSEIREMGRATQGVTLISVD-DG-SSLSGVRRVV--------------------------------------
------------
>tr|S5R407|S5R407_9PROT DNA gyrase subunit A OS=Candidatus Profftella armatura GN=gyrA PE=3 SV=1
-------HDYILCFSNYGRLYWLKVWQIPQGSRNSRGKPIINMFSNEKITVILPLSKNNYVFMSTSLGIVKKTLLSNFSNPRK--SGI---IAVNLSNED
FLIGAALT---DGSYD-MLFSDSGKAVRFNENSVRAMRARGVIGMRLEKK--VIALLVSNNKQSVLTATENGYGKRTLIKEYTKHNRGTKGIISI--NNG
K-VVAATLVN-YHEIMLITTGGILIRTRVSEIRKMGRSTQGVILITVEN-K-SKLCGVQRVM--------------------------------------
------------
>tr|H5T9S6|H5T9S6_9ALTE DNA gyrase subunit A OS=Glaciecola punicea DSM 14233 = ACAM 611 GN=gyrA PE=3 SV=1
-------HDHILCFSTRGRLYWLKVYQLPLASRNARGRPIVNILP-ERITAIL--PAGKYVFMATANGSVKKTELIHYSR-RA--NGI---IAVNLNDGD
ELIGVDLT---DGTCEIMLFSNAGKVVRFSEDQVRPMRATGVRGIRIA---TVVSLIIPNADGDILTATQNGYGKCTAVSEYPAKNRATKGVVSI--SNG
Q-VVGAVQVS-TDEIMLISDRGTLVRTRVSEVSRVGRNTQGVTLIRTVD-G-EHVVGLQRID--------------------------------------
------------
>tr|G4QGU4|G4QGU4_GLANF DNA gyrase subunit A OS=Glaciecola nitratireducens (strain JCM 12485 / KCTC 12276 / FR1064) GN=gyrA PE=3 SV=1
-------HDHILCFSTRGRLYWLKVYQLPLASRNARGRPIVNILP-ERITAIL--PAGKFVFMATTNGTVKKTELTQYSR-RA--NGI---IAVNLNDGN
ELIGVDLT---DGESEIMLFSDAGKVVRFSEDQVRPMRATGVRGIRLM---TVVSLIVPKGEGDILTATENGFGKRTPIEQYPAKSRATKGVVSI--SNG
L-VVGAIQVD-SKEIMLISDQGTLVRTRASEVSTVGRNTQGVRLIRTAE-D-ELVVGLQRID--------------------------------------
------------
>tr|W8X310|W8X310_CASDE DNA gyrase subunit A OS=Castellaniella defragrans 65Phen GN=gyrA PE=3 SV=1
-------HDYLLCFSDRGRVYWLKVWEVPQGSRNSRGRPIVNMFP-ETITVVLSVK-DHYVFMATSRGTVKKTPLSDFSNPRK--AGI---IAVGLDEGD
FLIGAELT---DGQHDVMLFSDAGKAVRFDENDVRPMRARGVRGMSLE--DGVIALLVAEDTQSVLTATENGYGKRTPIVEYTRHGRGTKGMIAIQTSNG
K-VVGAVLVQPEDEIMLITTGGVLVRTRVSEIREMGRATQGVTLINVD-EN-SLLSGVRRVV--------------------------------------
------------
>tr|A0A095Z5I9|A0A095Z5I9_9BURK DNA gyrase subunit A OS=Oligella urethralis DNF00040 GN=gyrA PE=3 SV=1
-------HDYLLCFSNHGRMYWLKVYAVPQGGRNSRGRPIVNLFP-ERINVVLPVK-DQYVFMATSKGTVKKTPLTDFSNPRR--GGI---IAVNLDEGD
FLIGAELT---DGKHDVMLFSDDGKAVRFDESDVRPMRARGVRGMNLD--DEVIALLVADDGRSVLTATENGFGKRTSITEYPRHRRGNKGVIAIQTSNG
K-VVGAVLVEEADEIMLITSAGVLVRTTVEQIREMGRATQGVTLINCD-EG-DFLTGVKRVV--------------------------------------
------------
>tr|H3NRC3|H3NRC3_9GAMM DNA gyrase subunit A OS=gamma proteobacterium HIMB55 GN=gyrA PE=3 SV=1
-------HATVLCFSNMGKVYWLKVFHIPLASRNARGRPMVNLLPDERITSILPIEEDQFIFMATANGTVKKTAATQFARQRS--VGL---RAIELDEDD
VLVGTAIT---DGNSDIMLFSSEGKATRFNESQVRAMRARGVRGINLADHK-LISLIVPKEGGRILTVTENGYGKRTENAEFPAKGRGGKGVIAMSTSNG
S-LVGAVQVWDTDEMMLISNQGTAVRTRVEEVSLLGRNTQGVRVIRTR-DG-EALVSVSRIV--------------------------------------
------------
>tr|B8KX24|B8KX24_9GAMM DNA gyrase subunit A OS=Luminiphilus syltensis NOR5-1B GN=gyrA PE=3 SV=1
-------HSTILCFSNLGKVYWLRVFNIPVASRNSRGRPMVNLLP-ERVTSILPVEAGSYIFMATAKGTVKKTEMTQFARQRS--VGL---RAIELEEGD
HLVGTAVT---DGSCDVMLFSSEGKAVRFNEAAVRPMRAKGVRGIRLGGYS-LISLIIPK-QGRILTVSENGYGKRSETADFPVRGRGTMGVIAMSTSNG
A-LVGAEQVWDGDEIMLISNQGTAVRTRIDEISLQGRNTQGVRVIRTR-DE-ESLVSISRIA--------------------------------------
------------
>tr|F3LEX0|F3LEX0_9GAMM DNA gyrase subunit A OS=gamma proteobacterium IMCC1989 GN=gyrA PE=3 SV=1
-------HDTILCFTNAGKVYWLKVFQIPLAGRQSRGRPIINLLPDERITSILPVREDHFIFMATANGTVKKTPLTQFARPRT--SGL---RAIDLEEDN
HLVGTAVT---DGNSDVMLFSSEGKAVRFNENDVRSMRSRGVRGIRLAEYE-VISMVLPT-DGKVLTVSENGYGKRTKVDEYATKGRAGKGMIAMQTSNG
K-VVGAVQVFDGDEIMLISDQGTMVRTHVDEVSVSGRNTQGVRVIKVK-DG-EHLMGVERIE--------------------------------------
------------
>tr|A0Z754|A0Z754_9GAMM DNA gyrase subunit A OS=marine gamma proteobacterium HTCC2080 GN=gyrA PE=3 SV=1
-------HATILCFSDLGKVYWLKVFHIPLASRNARGRPMVNLLP-ERITSILPVEEGHFIFMATARGIVKKTDMQQFARQRS--VGL---RALELEADD
WLVGTAVT---DGSCDVMLLSSEGKAVRFQEQAVRAMRARGVRGIKLGDHR-LISLIVPQ-DSTILTVSEKGYGKRTDTEEFPCKGRGTKGVIAMATTNG
P-LVGAVQVSTGDEIMLISDQGTAVRTRVEEISTLGRNTQGVRVIKTR-ED-EKLVRLSRIV--------------------------------------
------------
>tr|A4AAR3|A4AAR3_9GAMM DNA gyrase subunit A OS=Congregibacter litoralis KT71 GN=gyrA PE=3 SV=1
-------HDTLLCFTNLGKVYWIKVYQIPVAGRSSRGRPMVNLLQDERVTSILPLEDDRFIFMATAQGYVKKTDLASFA-PRS--AGL---RAIVLGEDD
VLVGTAIT---DGNQDVMLFSSEGKATRFSESAVRAMRSRGVRGINLADHR-MISLLVPDARGTVLTVSENGYGKRTTVDDFPTKGRGGKGVIAMASSNG
R-LVGALQVFSGDELMLISNQGTLVRTQCDQVSQLGRNTQGVRIIRTK-EG-ETLVRVERIV--------------------------------------
------------
>tr|U7PGK6|U7PGK6_STASI DNA gyrase subunit A OS=Staphylococcus simulans UMC-CNS-990 GN=gyrA PE=3 SV=1
-------HDHVLFFTNQGRVYKLKGYEVPELSRQSKGIPVINAIENEVISTMIAVKEDAFLIFATKHGIVKRSSLSNFSH-NR--NGK---IAINFRDED
ELVAVR-T---DG-KDVLLGTSRASLIRFKE--LRPLRAAGVKGITLR---GVIGLAVANGEDEVLVVTENGYGKRTPLEEYRVSNRGGKGIKTATITNG
D-IVCITTVTE-EDLMIVTNHGVIIRIDVGDISQNGRSAQGVRLIRLSEE--QFVSTVAKVQ--------------------------------------
------------
>tr|K9ALA6|K9ALA6_9STAP DNA gyrase subunit A OS=Staphylococcus massiliensis S46 GN=gyrA PE=3 SV=1
-------HDHILFFTNKGRVYKLKGYEVPELSRQSKGIPIVNALEKEVISTMIAVKEDDYLVFATKQGIVKRSRLNNFSR-NK--NGK---IAISFKDHD
ELIAVR-I---DG-QDILIGTKHASLIRFDE--LRPLRAAGVKGITLR---GVVGLDVAHKDDEILVVTDKGYGKRTNVNEYRLSNRGGKGIKTATLTNG
D-IVCITTVSD-EDLMIVTNLGVIIRLQVEDISQTGRATQGVRLIRLQDN--QFVSTVAKVK--------------------------------------
------------
>tr|A0A0D0RRZ5|A0A0D0RRZ5_STAGA DNA gyrase subunit A OS=Staphylococcus gallinarum GN=gyrA PE=3 SV=1
-------HDNVLFFTNKGRVYKLKGYEVPELSRQSKGIPVVNAIENEAISTMIAVKEEDYLVFATRKGIVKRSALSNFSH-NK--NGK---IAIGFKDDD
ELIAVR-T---DG-DDILIGTSHASLIRFPE--LRPLRAAGVKGITLR---GVVGLDVAKSNDEILVVTENGYGKRTPVNDYRLSNRGGKGIKTATITNG
N-IVCITTVNE-EDLMVVTNSGVIIRIDVQDISQNGRAAQGVRLIKLSDE--QYVSTVAKVS--------------------------------------
------------
>tr|A0A078M7I1|A0A078M7I1_9STAP DNA gyrase subunit A OS=Jeotgalicoccus sp. 13MG44_air GN=gyrA PE=3 SV=1
-------HDYILFFTNTGRVYRLKGYEIPELSRQSKGLPIVNLIEKEKISTMISVKEGYHLLFATKNGLAKRTPLDDFKQ-NK--NGK---IAISFRGED
ELLGVR-T---DG-KEVILGTREGSLVRFEE--VRSMRAAGVKGINLR---DVVGVDVLDP-QHVLVVTDKGYGKLTHEKEYRSINRGGFGVKTANLTNG
K-LVYIASVDD-EDMMIVTDKGVIIRLTIDTISITSRNTQGVRLIRLDEE--QDVATVAVVK--------------------------------------
------------
>tr|K9RE53|K9RE53_9CYAN DNA gyrase subunit A OS=Rivularia sp. PCC 7116 GN=gyrA PE=3 SV=1
-------HDSVLFFSERGVVYCMKAYQLPLGSRTSRGTPIVQMLPKEKITSIVPVSQDEYLVMLTKGGYIKKTALAAFSNIRA--NGL---IAISLEEGD
ELRWVRRA---RAEDSVIIGSRMGMAIHFRC--LRPLRTRGVKAMKLR---DLVGMDVLPAGLWVLVITTGGYGKRVPVGQFRLQNRAGQGLMATKFLQD
Q-LASLHIVS-DNEIMMVTSRGIIIRQAVNAISIQSRSATGVRVQRLDQ-D-DFLNGVAIVP--------------------------------------
------------
>tr|M1X013|M1X013_9NOST DNA gyrase subunit A OS=Richelia intracellularis HH01 GN=gyrA PE=3 SV=1
-------HDSVLFFSDRGVVYCLKAYQITMGSRTSRGTPIVQMLPKEKITSIIPVNDDEYLVMLTQGGNIKKTSLSAFSNIRA--NGL---IAISLEKGD
QLRWVRKA---KAEDSIIVGSRNGMAIHFRC--LRPLRTRGVRAMKLK---DLVGMDIIPAGPWVLVITNGGYGKRVPMPHFRLQNRAGQGLMVTKFSKD
K-LASLQIVK-EDEIMMVTNRGIIIRQAVNAISIQSRSATGVKVQRLDG-D-DAITGVAIVP--------------------------------------
------------
>tr|A0A099NMH9|A0A099NMH9_9BURK DNA gyrase subunit A OS=Taylorella equigenitalis GN=gyrA PE=3 SV=1
-------HDYVLCFSSLGRLHRLKVWEVPQGGRNSKGRPIVNLFE-EKITVVLPIK-DQFIFLATAKGVVKKTALSQYSSTRK--MAV---IAVTLDEDD
YLVGAELT---DGNSDIMLFSNAGKAVRFDESSVRATRSRGVLGMRLE--EGIISLIVSKNNAYVLTATENGYGKRTPVVEYTRHGRGTKGMIAIQTSNG
K-VVAAVLVDESDEIMLITTDGIVVRTKVAPIRELGRATQGVKLIRID-ND-TKLKGVQRVV--------------------------------------
------------
>tr|I7IKH8|I7IKH8_9BURK DNA gyrase subunit A OS=Taylorella asinigenitalis 14/45 GN=gyrA PE=3 SV=1
-------HDYVLCFSSLGRLHRLKVWEVPQGTRTSKGKPIVNLFD-ERITVVLPIK-DQFIFLATAKGIVKKTALSQYSSTRK--MAV---IAVTLDDDD
YLVGAELT---DGNSDIMLFSDAGKAVRFDESSVRATRSRGVLGMRLE--EGIISLIVSKDQASVLTATENGYGKRTAVTDYTRHGRGTKGMIAIQTSNG
K-VVAAVLVHPEDEIMLITTDGIVVRTKVEQIREMGRATQGVTLIRVD-QG-TKLSGVQRVV--------------------------------------
------------
>tr|A0A0R1TDH1|A0A0R1TDH1_9LACO DNA gyrase, A subunit OS=Lactobacillus paracollinoides DSM 15502 = JCM 11969 GN=FC17_GL000453 PE=4 SV=1
-------HDVLLFFTNAGKVYRMKGYEIPEYGRSAKGIPIINLLNDESIQAVINVSQEKYLFFTTLKGTVKRTPVDEFSN-RS--NGL---KALNLKDDD
ELINVS-V---DA-QNMIIGTHSGYAVSFQA--VRSMRATGVRGVRLR---DVVGSAILGPTSNVFVISEKGYGKQTPADEYAIKGRGGKGIKTINITNG
P-LAGLTSVNE-EDIMLITDKGVMIRFGVENVSQTGRATLGVHLIRLDDD--SKVATMAVVE--------------------------------------
------------
>tr|A0A0R1HQ24|A0A0R1HQ24_9LACO DNA gyrase, A subunit OS=Lactobacillus kimchicus JCM 15530 GN=FC96_GL001638 PE=4 SV=1
-------HDVMLFFTNTGKVYRMKGYEIPEYGRSAKGIPVINLLNNEHVESVINVSQNRYLFFTTLHGTVKRTPVEEFSN-RS--NGL---KAISLKEGD
EVMNVS-V---DD-QNMIIGTHRGYAASFQT--VRSMRATGVRGIRLR---DVVGAAVLAPNSNVFVISEKGYGKQTPASEYAIKGRGGKGIKTINVTNG
P-LAGLTTVTE-EDIMLITDKGVMIRFGVENVSETGRATLGVHLIRLDDE--STVATMAVVE--------------------------------------
------------
>tr|A0A0Q4HC94|A0A0Q4HC94_9MICO DNA gyrase subunit A OS=Agromyces sp. Leaf222 GN=ASE68_00805 PE=4 SV=1
-------HHWLLFFTNMGRVYRAKTYELQEGGRDAKGQHLANLLEPEQVAEILDIRAQ-YLVLATRDGLVKKTELTAYDT-RA--RGV---IAINLREGD
ELVSAM-----DEHDEILLVSRKGMSLRFEE--LRPMRTSGVKGMSFR-G-DLLEASVVAHDTYVFVVTEGGYAKSTRIEEYRKQQRSGLGIKVAKLNRG
D-LAGALIVST-DEVLVVLASGKVVRSDVAEVPA-GRDTMGVVFAKFAE-A-DRIIAIAKNS--------------------------------------
------------
>tr|K9PCW1|K9PCW1_CYAGP DNA gyrase subunit A OS=Cyanobium gracile (strain ATCC 27147 / PCC 6307) GN=gyrA PE=3 SV=1
-------HDALLLFSDRGVVYSIPAYRVPICSRSAKGTPIVQLLPREAITSLLAVSDDVQLVMLTSGGYIKRTRLSAFSNIRS--NGL---IAISLEDGD
ALRWVRLA---LPGDSVLIGSLKGMTIHFRL--LRPLRARGVRAMNLR---DLVSMDVLTAGPWVLVASASGLGKRVPVDQFRLQRRAGMGLRAIKF-GD
V-LVGLKVLG-GEELLLVSERGVIVRMKADAIPQQSRAATGVRLQKLDA-G-DRLTEVVLVP--------------------------------------
------------
>tr|A5GRY6|A5GRY6_SYNR3 DNA gyrase subunit A OS=Synechococcus sp. (strain RCC307) GN=gyrA PE=3 SV=1
-------HDSLLLFSDRGVVYSLPAYRVPIASRAAKGTPVVQLLPREQITSLLAVSEDVQLVMLTTGGFIKRTPLSAFSNIRA--NGL---IAINLEDAD
SLRWVRLA---RAGDSVLIGSINGMTIHFRI--LRPLRARGVRAMALR---DLVSMDVLPAGPWVLVATASGLGKRVPVDQFRLQRRAGLGLRGIKF-GD
A-LVGLCVMG-EEELLLVSERGVIVRLQSDVIPQQSRAATGVRLQRLDK-G-DRLAEVVLVP--------------------------------------
------------
>tr|B1X5H0|B1X5H0_PAUCH DNA gyrase subunit A OS=Paulinella chromatophora GN=gyrA PE=3 SV=1
-------HDTLLLFSDRGISYALPAYRVPVSSRSAKGTPVVQILPREEITSLLSVSNEVQLLMLTNSGFIKRTRLSAFSNIRS--NGL---IAINLELGD
ALRWVRLA---LPGDSVLIGSIQGMTIHFRI--LRPLRARGVRAMNLR---DLVSMDVLPAGPWVLVASASGLGKRVPVNQFRLQRRAGMGLRAMRF-GD
V-LVGLKVLG-REELLLVSEKGVIVRMQADLIPQQSRAATGVRLQKLDD-G-DHLAEIVLIP--------------------------------------
------------
>tr|A0A0R2U956|A0A0R2U956_9CYAN DNA gyrase subunit A OS=cyanobacterium BACL30 MAG-120619-bin27 GN=ABR96_02570 PE=4 SV=1
-------HDNLLLFSDRGVVYTVPAYRVPISSRAAKGTPIVQMLPREQITSLLAVSDDGVLVMLTSGGTIKRTRLSAFANIRS--NGL---IAIDLVEGD
ALTWVRLA---LPGDSILIGSRNGMTIHFRL--LRPLRARGVRAMNLR---DLVSMDVLPAGPWVLVASASGLGKRVPVDQFRLQKRAGMGLRAIKF-SD
V-LVGLKVLG-GEELLLVSEKGVIVRTQADAVPQQSRAATGVRLQKLDA-R-DRLSEVVLVP--------------------------------------
------------
>tr|J0UX33|J0UX33_ALCFA DNA gyrase subunit A OS=Alcaligenes faecalis subsp. faecalis NCIB 8687 GN=gyrA PE=3 SV=1
-------HDYLLCFSNRGRVYWLKVWEVPQGSRNSRGRPIVNMFP-EKINVVLSVK-DQFVFMATSRGTVKKTPLSDFSNPRK--AGI---IAVGLDEGD
YLIGAQLT---DGVHDVMLFSDAGKAVRFDEGDVRPMRARGVRGMTLE--EGVIALLVAEDTQSVLTATQNGFGKRTPIGEYTRHGRGTKGMIAIQTSNG
K-VVGAVLVRETDEIMLITNAGVLVRTRVAEIREMGRATQGVTLISVD-DD-SELSGVYRVV--------------------------------------
------------
>tr|L8D7E8|L8D7E8_9GAMM DNA gyrase subunit A OS=Pseudoalteromonas luteoviolacea B = ATCC 29581 GN=gyrA PE=3 SV=1
-------HDTILCFSTAGRLYWLKVYQLPLASRTARGKPIVNLLP-ERITAIL--PEDKYVIMATADGTVKKTSLIEYSR-RS--SGI---IAINLKEGD
SLIGVDIT---DGSSEIMLFSDAGKVVRFKEGGVRPMRATGVRGIKLA---DVVSLIVPKNDGAVLTVTENGYGKRTPLEEYPVKGRATQGVVSI--SNG
K-VVGAVQVQ-NDEIMLISNRGTLVRTRVNEVSVVGRNTQGVILIRTID-G-EQVVGLQRID--------------------------------------
------------
>tr|A0A031GFL3|A0A031GFL3_MICLU DNA gyrase subunit A OS=Micrococcus luteus GN=gyrA PE=3 SV=1
-------HHWLLFFTNFGRVYRIKTYELLEAGRDAKGQHVANLLAPERIAQIQPLVAP-YLVLATRGGLVKKTPLLDYDT-RT--AGL---IAIKLREGD
ELVSAR-----SPDDDLILISHKGQSLRFTE--LRPMRTSGVTGMKFR-D-DLLTMDVVEEDGYVFTVTDGGFAKRTHVDEYRLQNRGGLGIKVAKLVRG
E-LAGGLVVRD-QEVLVVMASGKVVRSAVAGVPA-GRDTMGVIFAKPDK-R-DRIVAVTLNN--------------------------------------
------------
>tr|A0A0K1NCX3|A0A0K1NCX3_9BURK DNA gyrase subunit A OS=Ottowia sp. oral taxon 894 GN=gyrA PE=3 SV=1
-------HDYILCFSNRGKLYWLKVWEAPSGSRGSRGRPIVNMFP-EKITVVLPLT-DRYVFMATAGGTVKKTALNEFSNPRK--AGI---IAVGLDEGD
YLIGAALT---DGKHDVMLFSDGGKAVRFDENDVRHMRARGVRGMNLE--EGVIAMLVAEARNSVLTATENGYGKRTHISEYTRHGRGTKGMIAIQQSNG
K-VVAATLVNADDEIMLITDKGVLVRTRVAEIREMGRATQGVTLIALD-DG-ARLSGLQRIV--------------------------------------
------------
>tr|Y5PE17|Y5PE17_9STAP DNA gyrase subunit A OS=Staphylococcus sp. M0480 GN=gyrA PE=3 SV=1
-------HDNVLFFTNKGRVYKLKGYEVPELSRQSKGIPVINAIENEVISTMIAVRENSFLVFATKKGIVKRSALSNFSH-NK--NGK---IAIGFKEDD
ELIAVR-T---DG-QDILLGTAHASLIRFPE--LRPLRASGVRGISLR---NVVGLDVAYAEDEVLVVTEKGYGKRTPVSEYRLSNRGGKGIKTAKITNG
N-VVCITTVSQ-EDLMIVTDGGIIIRLQVEDISQNGRATQGVRLMKLGDN--QAVSTVAKVI--------------------------------------
------------
>tr|H0DJU0|H0DJU0_9STAP DNA gyrase subunit A OS=Staphylococcus pettenkoferi VCU012 GN=gyrA PE=3 SV=1
-------HDHVLFFTNKGRVYKLKGYEVPELSRQSKGIPVINAIENESISTMIAVKEDHFLVFATKRGIVKRSALSNFSH-NK--NGK---IAISFKEDD
ELIAVR-T---DG-EDILIGTAHASLIRFQE--LRPLRAAGVKGISLR---NVVGLDVAHEEDEVLVVTEKGFGKRTPVSDYRLSNRGGMGIKTATITNG
N-IVCITTVTD-EDIMVVTNHGVIIRMEAQDISQNGRAAQGVKLIRLGEN--QHVATVAKVN--------------------------------------
------------
>tr|E6MCA7|E6MCA7_STALU DNA gyrase subunit A OS=Staphylococcus lugdunensis M23590 GN=gyrA PE=3 SV=1
-------HDHVLFFTNKGRVYKLKGYEVPELSRQSKGIPVVNAIENESISTMIAVNEGNYLIFATKNGIVKRSALSNFSH-NK--NGK---IAIGFKEDD
ELIAVR-T---DG-QDILIGTAHASLIRFAE--LRPLRAAGVKGITLR---GVVGLDVAHSEDEVLVVTENGYGKRTPVGEYRLSNRGGKGIKTATITNG
N-VVCITTVTE-EDLMIVTNGGVIIRLDVQDISQNGRAAQGVRLMRLGNE--QFVSTVAKVQ--------------------------------------
------------
>tr|A0A0P9G212|A0A0P9G212_9GAMM DNA gyrase subunit A OS=Pseudoalteromonas sp. P1-9 GN=gyrA PE=4 SV=1
-------HDTILCFSTSGRLYWLKVYQLPLASRAARGKPIVNLLP-ERITTIL--PADKYVLMATANGTVKKTPLTAYSR-RA--SGI---IAINLNEGD
SLIGADIT---DGTNDIMLFTDHGKVVRFNEKALRPMRATGVRGIKMP---DVVSLIVPKNDGPVLTITENGYGKRTLLEDYPAKSRATQGVVSI--SNG
K-VVGAVQVE-NDEIMIISNKGTLVRTRVNEVSTVGRNTQGVILIRTAD-D-EQVVGLQRID--------------------------------------
------------
>tr|A0A066TD21|A0A066TD21_9GAMM DNA gyrase subunit A OS=Gilliamella apicola GN=gyrA PE=3 SV=1
-------HDTILCFSSRGRLYWMKVYQLPEASRGSRGRPIINLLP-ERITAIL--PDEHCVFMATAQGTVKKTSLIEFSR-RS--GGI---IAINLRDDD
ELIGVDLT---SNTEDIMLFSANGKVVRFPANKVRCMRAAGVRGIKLD---DVVSLIVPRGSGAILTATQNGYGKRTQQELYPTKSRATKGVISI--SNG
T-VVGAVQVD-TDQIMLITDAGTLVRTRVSEVSIVGRNTQGVMLIRTAD-N-EKVVGLQRIA--------------------------------------
------------
>tr|A0A0P7ZJJ0|A0A0P7ZJJ0_9CYAN DNA gyrase, A subunit OS=Phormidesmis priestleyi Ana GN=gyrA-2 PE=4 SV=1
-------HDHVLFFTDKGISYSLRAYQIPESSRTAKGYPLVQMLPKEKVTSVISVSADEYLVMLTQGGFVKKTALSAFSRIRT--NGL---IAISLEEGD
ELRWVRLA---RSEDSILIGSQRGMTIHFKT--LRPLRTKGVRAMSLR---DLISMDILSSGPWVLVVSAGGLGKRVPVSNFRLQNRAGMGLVAMKFDND
E-LVALRIAS-DDELMIVSQRGIIMRQAIDAISIQSRMATGVQLQKLDN-D-DAIAAVALVP--------------------------------------
------------
>tr|N8VCC7|N8VCC7_9GAMM DNA gyrase subunit A OS=Acinetobacter sp. ANC 3789 GN=gyrA PE=3 SV=1
-------HATVLCFTNVGKVYRLRVFEVPQASRGAKGRPMVNLLPAETITAILPLTENHYVFMATASGTVKRVELAQFANIRA--NGL---RAIELNEED
TLIGVAIT---DGNQQIMLFSNEGKAIRFA---VRAMRAKGVRGMRVAATVIIVSLVVVP-TGEVLCASANGYGKRTPVDDFPTKKRGGKGVIAI--SNG
E-LVGAVAID-TKELMLISDGGTLVRTRASEVATTGRNAQGVRLIRLGE-N-ETLVGVEAID--------------------------------------
------------
>tr|A9KPP6|A9KPP6_CLOPH DNA gyrase subunit A OS=Clostridium phytofermentans (strain ATCC 700394 / DSM 18823 / ISDg) GN=gyrA PE=3 SV=1
-------HHYIMFFTNKGRVYRLKAYEIPESSRTARGTAIVNLLQPERITAIIALKDNRYLFMATKDGIVKKTKIKEYQN-RK--TGL---QAINLREDD
ELIEVK-T---NS-KDIVLVTKNGMCIRFHE--VRNTRSMGVIGMNLT---GVVAMQIHTQGKYLLTVSEYGLGKLTDLDEFTPQRRGGKGVKCYKITTG
N-VVGAKAVNE-HEVMIITNEGIIIRLEVNGISILGRITSGVKLINIDAG--IRVASLAKVK--------------------------------------
------------
>tr|R5WDH5|R5WDH5_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:167 GN=gyrA PE=3 SV=1
-------HHYLMFFTNKGRVYRMKAYEIPESGRTSRGTAIVNLLQPEKISAVISLKDEEYLFMATKSGIVKKTHISEYEN-RK--TGL---QAINLREDD
ELIEVK-T---NN-KDIILVTKHGMCIRFKE--VRPTRSIGVRGMNLG---EVVGMQMDTQGPNILLVSEFGMGKRTAVEDFSVQHRGGKGVKCYKITTG
D-VVGAKAVEG-TEVMLITNEGIIIRINVDDISILGRVTSGVKLMNLDSTN-IKIASIAKVR--------------------------------------
------------
>tr|R7C8W1|R7C8W1_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:62 GN=gyrA PE=3 SV=1
-------HHYLMFFTNLGKVYRMKAYEIPEASRTSRGTAIINLLQPEKISAVISIKEDKYLFMATKDGTVKKTPILEYAN-RK--TGL---QAITLRDGN
ELIEVK-T---DN-RDIFLVTKRGQCIRFNE--VRTTRSIGVRGMKID---GVVAMQMDIQGPNLLMVSEFGMGKRTSIDEFAPQFRGGKGVKCYKITTG
N-VIGCKAVEG-TEIMLITTEGIIIRIGVDDISQLGRVTSGVKLMNLDSSD-IRIASIARVH--------------------------------------
------------
>tr|R5EG74|R5EG74_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:590 GN=gyrA PE=3 SV=1
-------HHYLMFFTNSGKVYRMKTYEIPESARTSRGTNIVNLLQPERITAVIALKEGKYLFMVTKNGIVKKTPIMDYAN-RK--TGL---AAITLKDGD
ELIEVK-T---DN-KDIIMVTKLGMCIRFNE--VRSTRSQGVIGMNLS---GIIGMQMDTQGEDLLIVSENGMGKRTSMEEFTPQRRGGKGVKCYKINTG
N-VVGMKAVND-NEIMLISTEGIVIRLECSSISELGRITSGVKLMKMDEGD-ITVASIAKVR--------------------------------------
------------
>tr|A0A0K8J1P4|A0A0K8J1P4_9FIRM DNA gyrase subunit A OS=Herbinix sp. SD1D GN=gyrA PE=3 SV=1
-------HDYIMFFTNQGRVYRLKAYEIPEASRTARGMAIINLLQPEQITAIIPIKEDRYLFMATKYGMVKKTPIKDYEN-RK--SGL---IAINLREGD
ELIEVK-T---NG-KDVFLVTKKGMCIRFDE--VRPTRSMGVIGMSLD---DIIGMQLDTQGEYLLFVSAKGLGKRTAIDEFKVQFRGGKGVKCYKLTTG
E-VVGVKAVNE-NEIMLITTEGIIIRILVSDISILGRITSGVKLINLDDEN-VFVASLAKVR--------------------------------------
------------
>tr|R7I547|R7I547_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:411 GN=gyrA PE=3 SV=1
-------HHYVNFFTNMGRVYRIKAYEIPEASRTARGTALVNLLQPERITAVIPIRDHKYLFMATKKGIVKKTSLTDYSK-RK--SGL---QAINLRDDD
ELIEVK-T---NG-KDIFLVTKYGMCIRFSE--VRPTRSMGVIGINLT---QVVGMQLQTQGSHLLIVSENGLGKRTALEEFSLQYRGGKGVKCYKITTG
N-IVGVKAVND-NEIMLITTEGIIIRTMCNQISELGRITSGVKLMNIDRDD-IKVASIAKVR--------------------------------------
------------
>tr|R6YJP8|R6YJP8_9FIRM DNA gyrase subunit A OS=Roseburia sp. CAG:309 GN=gyrA PE=3 SV=1
-------HHYLMFFTNKGRVYRIKAYEIPESSRTSRGTAIVNLLQPEKITAVIALREDKYLFMATKNGLVKKTSLSEYMN-RK--TGL---QAINLREED
ELIEVK-T---DD-KEIILVTKQGQCIKFKE--VRTTRSMGVRGMNLS---DVVGMQLDTQGEQLLLVSEYGLGKRTNIEEFGVQHRGGKGVKCYKITTG
N-VVGAKAVHD-QEIMLITNEGIVIRIEVSGISILGRITSGVKLMNLDPSD-VVIASIAKVR--------------------------------------
------------
>tr|A0A0H5SZ93|A0A0H5SZ93_9FIRM DNA gyrase subunit A OS=Herbinix hemicellulosilytica GN=gyrA3 PE=3 SV=1
-------HHFIMFFTNQGRVYRLKTYEIPEAGRTARGTAIINLLQPEKITAVIPIKDNRYLFMATKKGIVKKTSVKEYEN-RK--SGL---IAINLREDD
ELIEVK-T---DG-KDVFLVTKNGMCIRFNE--VRPTRSTGVIGMAID---DIVGMQLNSQGEYLLIASANGMGKRTSIDEFSLQHRAGKGVKCYKITTG
N-VVGVKAVNE-NEVMLITTEGIIIRIMVSDIPVLGRITSGVKLIHLDNDN-VYVASLAKVR--------------------------------------
------------
>tr|R7JYH7|R7JYH7_9CLOT DNA gyrase subunit A OS=Clostridium sp. CAG:277 GN=gyrA PE=3 SV=1
-------HHYLMFFTNKGRVYRLKAYEIPESGRTARGTAIINLLQPEKINAVIPIRENRYLFMATKKGIVKKTSIKDFAN-RK--TGL---QAINLRDDD
ELIEVK-T---NK-KDIILVTKHGQCIRFSE--VRPTRTMGVIGMNLT---DVVGMQLDTQGDYLVLVSEYGMGKRTRIEEFTPQHRGGKGIKCYKITTG
N-VVSVKAVNE-NEIMLITTEGIIIQMRVDEISVLGRITSGVKLIDLDPDD-IVVATMAKVR--------------------------------------
------------
>tr|Q7VKW4|Q7VKW4_HAEDU DNA gyrase subunit A OS=Haemophilus ducreyi (strain 35000HP / ATCC 700724) GN=gyrA PE=3 SV=1
-------HDTILCFSSRGRLYQLKVYQLPQASRGARGTPIVNILPEERITAILPIPTDKFIFMATASGIVKKVCLDAFSH-RS--SGL---ITLKLREGD
ELIGVDIT---DGGSEIMLFSAQGRVVRFAEKAVRSMRATGVRGIKLASINIVVSLVIPRASGDILTVTENGYGKRTVLTEYPIKSRATKGVLSI--NNG
K-VVAAVQVD-LDQIMLITDAGTLVRTRVAEVSLVGRNTQGVRIIRTAE-D-EKVVSLERLC--------------------------------------
------------
>tr|C9PPR5|C9PPR5_9PAST DNA gyrase subunit A OS=Pasteurella dagmatis ATCC 43325 GN=gyrA PE=3 SV=1
-------HDTILCFSSRGRLYWLKVYQLPQASRGSRGRPIVNILP-ERITAIL--PEDKFVVMATAGGIVKKISLTEFSR-RS--SGI---IALNLRDED
ELIGVDIT---DGSNEIMLFSAQGRVVRFSESAVRAMRATGVRGIKLATDNVVVSLVIPKNQGAILTATQNGYGKRTELVEYPTKSRNTKGVISI--SNG
K-VVAATQVE-TDQIMLITDAGTLVRTRVNEISVVGRNTQGVRLIRTTE-D-ETLVGLQRVC--------------------------------------
------------
>tr|R9PKU2|R9PKU2_AGAAL DNA gyrase subunit A OS=Agarivorans albus MKT 106 GN=gyrA PE=3 SV=1
-------HDTVLCFSTVGKVYWMKVYQLPLASRQARGKPIVNLLP-ERITAIL--PEDKFILFATANGTVKKTPLTAFKR-LS--SGI---RAINLNDDD
KLIGVDIT---NGNNEIMLFSDAGKVVRFNEKALRPMRAAGVRGISLD---GVVSLIVPTGDGDILTATENGYGKRTKLDEYPAKSRATKGVVSI--SNG
L-VVGAVQVT-AQEMMLITNGGTLVRTRVNEVSLVGRNTQGVTLIRTSE-D-EKVVGLQRID--------------------------------------
------------
>tr|X7E1T8|X7E1T8_9GAMM DNA gyrase subunit A OS=Marinomonas ushuaiensis DSM 15871 GN=gyrA PE=3 SV=1
-------HDTIMLFSNFGKVYWMRVFDIPVASRGAKGRPIVNLLPRESISALLPLPASSYIFMATANGTVKKTALQHFARPRS--TGL---IALSLDETD
ELVGVSVT---NGESDIMLVSSSGKTIRFKESDVRPMRAAGVRGIRLSEAK-VVSLIVPQNDLAVLMACENGFGKRTLVDDFPVYGRGGQGVIGIQVSNG
P-VIGAAQVDETDEIILITDQGTLVRTRVTEVSCQGRNTQGVTLIRLT-ND-EHLVGIERVV--------------------------------------
------------
>tr|F2JXC4|F2JXC4_MARM1 DNA gyrase subunit A OS=Marinomonas mediterranea (strain ATCC 700492 / JCM 21426 / NBRC 103028 / MMB-1) GN=gyrA PE=3 SV=1
-------HDTVMLFSNFGKVYWLRVFEIPVASRTAKGRPIVNLLP-EHISALLPLNEDSYIFMATANGTVKKTAVEYFARPRS--TGL---IALSLDEND
ELVGVAQT---SGENDIMLVSSSGKTIRFKESDVRAMRAAGVRGIRLADYK-VVSLIVPQ-GCSVLFACENGFGKRTLTEDFPVYGRGGQGVIGIQVSNG
P-VVGATQVEDTDEIMLISDQGTLVRTRASEVSCQGRNTQGVTLIRLM-ND-EHLVGVERVV--------------------------------------
------------
>tr|F6CVE7|F6CVE7_MARPP DNA gyrase subunit A OS=Marinomonas posidonica (strain CECT 7376 / NCIMB 14433 / IVIA-Po-181) GN=gyrA PE=3 SV=1
-------HDTVMLFTNFGKVYWLRVFEIPVASRSSKGRPIVNLLPAEHVSALLPLTASSYIFMATANGTVKKTAMEHFARPRS--TGL---IALNLDETD
ALVGVAQT---SGEDDIMLVSSSGKTIRFSEGDVRAMRAAGVRGIRLGEAK-VVSLIVPQEGAAVLMACENGYGKRTLVDDFPVYGRGGQGVIGIQVSNG
P-VVGATQVEETDEIMLITDQGTLVRTRVSEVSCQGRNTQGVTLIRLT-ND-EHLVGVVRVE--------------------------------------
------------
>tr|A3Y7B6|A3Y7B6_9GAMM DNA gyrase subunit A OS=Marinomonas sp. MED121 GN=gyrA PE=3 SV=1
-------HDTIMLFSNFGKVYWLRVFEIPVASRNAKGRPIVNLLPSESISALLPLVAESFIFMATANGTVKKTAMQHFARPRS--TGL---IALSLDESD
ELVGVSIT---NGNDDIMLVSSTGKTIRFKESDVRAMRAAGVRGIKLAEAK-VVSLIVPEEGMSVLTACEHGYGKRTAIDDFPVYGRGGQGVIGIQVSNG
P-VVGAVQVADDDEIILITDQGTLVRTRVSEVSCQGRNTQGVTLIRLT-NE-EQLVGVVRVV--------------------------------------
------------
>tr|A0A0K6IH40|A0A0K6IH40_9GAMM DNA gyrase subunit A OS=Marinomonas fungiae GN=gyrA PE=3 SV=1
-------HDTVMLFSNFGKVYWLRVFEIPVGSRASKGRPIVNLLPAEHISALLPLTASSYIFMATANGTVKKTAMEHFARPRS--SGL---IALKLDESD
ALVGVAQT---SGNDDIMLVSSSGKTIRFKETDVRSMRAAGVRGIKLAEAK-VVSLIVPSAETAVLMACENGYGKRTMISEFPVYGRGGQGVIGIQVSNG
P-VVGATQVEESDEVILITDMGTLVRTRVAEISCQGRNTQGVTLIRLS-ND-ERLVGVERVV--------------------------------------
------------
>tr|B1XVQ8|B1XVQ8_POLNS DNA gyrase subunit A OS=Polynucleobacter necessarius subsp. necessarius (strain STIR1) GN=gyrA PE=3 SV=1
-------HDTILCFSDRGRMYWLKVWEVPQGSRTSRGKPIVNMFP-EKITVILPIK-NQYVFMATSLGTVKKTRLSDFSNPRK--AGI---IAVDLNEND
FLVGAAIT---DGQHDVMLFSDAGKAVRFDENDVRPMRARGVRGMNLG--EGVIAMLVAPAPSSVLTATENGYGKRTPITEYTRHGRGTKGMIAIQTSNG
K-VVAAALVSPEDQIMLITTGGVLVRTRVSEIREMGRATQGVTLINVD-EG-TRLSGLQRIA--------------------------------------
------------
>tr|A9GW54|A9GW54_SORC5 DNA gyrase subunit A OS=Sorangium cellulosum (strain So ce56) GN=gyrA PE=3 SV=1
-------HSYVFFFSDKGKVFVKKVYEIPQAPRNAKGRAIVNFV-PEKVAAITPVPGETFVVTLTRRGQIKKTALNEYENYRD--KGI---IGVRIEEGD
QLFTAA-T---DGKRELVIATRSGMSIRFPE--VRPTRTMGVKGIELD---DVVGLGVSGDRDRVLAVCERGYGKQTPLEEFRLQSRGGKGVILI--SNG
P-VVGVAMVSPSDEVLIVTDRGQMIRTKTSEIRETGRNAQGVRIMHVGQ-D-ERVVAVEAFA--------------------------------------
------------
>tr|A0A077DE29|A0A077DE29_9BURK DNA gyrase subunit A OS=Basilea psittacipulmonis DSM 24701 GN=gyrA PE=3 SV=1
-------HDYLLCFSNYGRLYWLKVWQVPQGTRGSRGRPIVNMFP-ERITATLPVK-DQYVFMATSRGTVKKTPLSDFSNPRK--AGI---IAVGLKEDD
YLIGVGLT---NGQSDVMLFSDAGKAVRFSESDVRPMRASGVRGMNLD--KDVIAMLVTSDGFSVLTATENGYGKRTAIEEYTRHGRGTKGMIAIQTSNG
K-VVAATLVKETDEIMLITNGGVLVRTRVSEIREMGRATQGVTLIRID-DD-TKLQGVSRVA--------------------------------------
------------
>tr|V8FRQ0|V8FRQ0_9BURK DNA gyrase subunit A OS=Pelistega indica GN=gyrA PE=3 SV=1
-------HDYLLCFSNHGRVYWLKVWEVPQGTRNSRGKPIVNLFN-ERITVVLAVK-NQYVFMATAQGTVKKTPLSDFSNPRK--AGI---IAVNLDEGD
YLIGAELT---DGKHDVMLFSDAGKAVRFDENDVRSMRARGVRGMNLE--EGVISLLVAGDEQSVLTATENGFGKRTSITEYTRHSRGTKGMIAIQTSNG
K-VVAAVLVEPSDEIMLITTGGVLVRTKVDQIREMGRATQGVTLIRVD-EG-TVLSGIRRVA--------------------------------------
------------
>tr|A0A0J6NK53|A0A0J6NK53_9NEIS DNA gyrase subunit A OS=Chromobacterium sp. LK11 GN=gyrA PE=3 SV=1
-------HDFVLCFSSRGRCYWRKVYDLPQGGRQSRGKPMVNVLP-EKINALLPVK-DQYVFMATADGTVKKTPLRAFSKPRA--AGI---IAINLDEGN
YLIGVALT---CGGDQVMLFSDAGKSVRFSE-QVRPMRSRGVRGMKLG--EGLISLLVTNSDQMVLTASNGGYGKRTRTGDFRLTSRGTQGVIAMDLTTG
FKLVAASLVEETDDVMLITTGGVLIRTKVAEVRETGRSAQGVRLINLD-EG-EQLIGLEKVA--------------------------------------
------------
>tr|C1D8N0|C1D8N0_LARHH DNA gyrase subunit A OS=Laribacter hongkongensis (strain HLHK9) GN=gyrA PE=3 SV=1
-------HDFLLCFSSAGRMYWLKVYELPQGSRQSRGKPIVNLLP-EKINAILPVK-TEYVFMATARGTVKKTPLSAFSNRRS--AGI---IAVDLDEGD
YLIGAAVT---SGNSEVMLFSDAGKAVRFDE-DVRPMRARGVRGMELG--DAVIGMLVSNETSQVLTATANGYGKRTPIGDYRKSRRGTQGVIAIDTGNG
A-LVAVALVADSDELMLMTTGGVLIRTRVSEVRETGRAAQGVRLINLD-AG-EQLVSLEKIA--------------------------------------
------------
>tr|A0A0J6PB84|A0A0J6PB84_CHRVL DNA gyrase subunit A OS=Chromobacterium violaceum GN=gyrA PE=3 SV=1
-------HDYVLCFSSRGRCYWRKVYDLPQGGRQSRGKPMVNVLP-EKINALLPVK-DQFVFMCTANGTVKKTPLVDFSRPRT--AGI---IAVNLDDGD
NLIGVALT---HGDDQIMLFSDAGKAVRFSE-DVRPMRATGVRGMMLG--DDVISLLVSNSQQMVLTASDGGYGKRTCVGDFRRTSRGTQGVIAMDLTTG
LKLVAASLVEETDDIMLITTGGVLIRTKVAEVRETGRSAQGVRLINLD-EG-EKLIGLEIVA--------------------------------------
------------
>tr|A0A0K6H1G8|A0A0K6H1G8_9NEIS DNA gyrase subunit A OS=Gulbenkiania indica GN=gyrA PE=3 SV=1
-------HDYVLCFSSFGRCYWIKVYDLPQGGRASRGKPMVNVLA-ERINALLPVK-DQYIFMATANGTVKKTPLVDFSRPRT--AGI---IAVNLDEGD
NLIGVALT---HGNDQIMLFSDTGKAVRFNE-DVRAMRATGVRGMALA--EGVISLLVTNSEQMVLTASDGGYGKRTRIGEFRHTSRGTQGVIAMDLTTG
LKLVAASLVEETDDVMLITTGGVLIRTKVAEVRETGRAAQGVRLINLD-EG-EKLIGLEKVA--------------------------------------
------------
>tr|A0A0J5JEU4|A0A0J5JEU4_9NEIS DNA gyrase subunit A OS=Vogesella sp. EB GN=gyrA PE=3 SV=1
-------HDYVLCYSSFGRCYWIKVYDMPQGGRTSRGKPIVNVLP-EKINAMLPVKKGPFVFMCTANGTVKKTPLEAFSRPRS--AGI---IAVKLDEGD
KLVGVALT---SGNDQIMLFSNAGKAVRFDE-GVRAMRATGVRGMALG--EGVISLLVANSEQQVLTASDGGYGKRTRVGEFRHTSRGTQGVIAMDLTTG
LALVTASLVEDSDDVMLITTGGVLIRTKVDQVRETGRAAQGVRLINLD-DG-EKLICLVKVA--------------------------------------
------------
>tr|A0A0F3KW29|A0A0F3KW29_9NEIS DNA gyrase subunit A OS=Aquitalea magnusonii GN=gyrA PE=3 SV=1
-------HDYVLCFSSKGRCYWIKVYDLPQGGRNSRGKPMVNVLP-EKINALLPIKKGPFIFMCTANGTVKKTPLEAFSRPRT--AGI---IAVRLDEGD
NLIGVALT---SGNDQIMLFSDAGKAVRFSE-DVRAMRAGGVRGMMLG--EGVISLLVTNSEQQVLTASDGGYGKRTRTGEFRHTSRGTQGVIAMDLTTG
LKLVAASLVEDSDDVMLITTGGVLIRTKVSEVRETGRSAQGVRLINLD-EG-EKLIGLEKVA--------------------------------------
------------
>tr|R6XCH3|R6XCH3_9FIRM DNA gyrase subunit A OS=Firmicutes bacterium CAG:313 GN=gyrA PE=3 SV=1
-------HDNLLFFTNFGKVYLLKAYQIPG-SRISKGLPLINLLKAEKLAAVINVKEPGYVIFGTKNGIIKKTELIQYKNIRS--TGI---RAIILGEQD
ELIAVART---NGRQDIIFGASNGKAACFN---VRATRASGVKGIRVA---RAIGLVAVN-EDEITVVTEFGYGKRTPTSDFKIKGRNGKGVKYMNITSG
R-PVSLAPST-EDDLMIITDKGMVIRTYLADISV-GRDTQGVRVIKLN-EG-QTVSSIAIVP--------------------------------------
------------
>tr|R6UDD9|R6UDD9_9STAP DNA gyrase subunit A OS=Staphylococcus sp. CAG:324 GN=gyrA PE=3 SV=1
-------HDNLLFFSNFGKVYLLKAFQIPA-SRISKGLPIVNLLKDEKLAAVINVKEPGYIIFGTKNGIIKKTELIQYKNIRS--TGI---RALILNEDD
ELIAVART---TGNQDIIFGASNGKAACFN---VRATRASGVKGIRVA---KAIGLVVVN-EDEITVVTEYGFGKRTPTSDFKIKGRNGKGVKYMNITSG
R-PVSLASST-DDDLIIITDKGMVIRTYLNDISL-GRDTQGVKLIKLN-EG-HLVSTIAIVP--------------------------------------
------------
>tr|V2TZ55|V2TZ55_9GAMM DNA gyrase subunit A OS=Acinetobacter nectaris CIP 110549 GN=gyrA PE=3 SV=1
-------HSTVLCFTNVGKVYRLKAFEVPQASRGAKGRPIVNLLPPETITAILPVKEDHYVFMATASGTVKRVDLSQFSNVRS--NGL---RAIELNEED
TLIGVAIT---DGKQQIMLFSNEGKAIRFA---VRAMRARGVRGMRVTAALIIVSLVVVP-NGEVLCACAKGYGKRTPVDDFPTKKRGGKGIIAI--SNG
E-LVGAVSID-SKEMLLISDGGTLVRTRASEVATTGRNAQGVRLIRLQE---EVLVGVVSIE--------------------------------------
------------
>tr|A0A0M2NYA8|A0A0M2NYA8_STACC DNA gyrase subunit A OS=Staphylococcus cohnii subsp. cohnii GN=gyrA PE=3 SV=1
-------HDHVLFFTNKGRVYKLKGYEVPELSRQSKGIPVVNAIENETISTMIAVKEEDYLVFATLNGIVKRSALRNFSH-NK--NGK---IAIGFKEDD
ELIAVR-T---DG-DDVLIGTAHGSLIRFNE--LRPLRAAGVKGITLR---GVIGLDVTKADDEILVVTENGYGKRTPVSEYRLSNRGGKGIKTATITNG
Q-VVCITSVEK-EDLMIVTNAGVIIRIGVEDISQNGRAAQGVRLIKLNDD--QFVSTVAKVD--------------------------------------
------------
>tr|A0A0Q9XS55|A0A0Q9XS55_9STAP DNA gyrase subunit A OS=Staphylococcus sp. NAM3COL9 GN=ACA31_00920 PE=4 SV=1
-------HDHVLFFTNKGRVYKLKGYEVPELSRQSKGIPVVNAIESESISTMIAVKEENYLVFATLKGRVKRSALSNFSH-NR--NGK---IAINFKEDD
ELIAVR-T---DG-TDILIGTAHASLIRFHE--LRPLRAAGVKGITLR---GVVGLDVTKADDEILVVTENGYGKRTPVGDYRLSNRGGKGIKTATITNG
N-IVCITSVTE-EDLMVVTNSGVIIRIDVDDISQNGRAAQGVRLIKLDDN--HFVSTVAIVD--------------------------------------
------------
>tr|A0A0M1E516|A0A0M1E516_STEMA DNA gyrase subunit A OS=Stenotrophomonas maltophilia GN=gyrA PE=3 SV=1
-------HDTLLTFTSSGKVFWLPVYQLPEAGSNARGRPIINWIP-ERVQAVLPVRDGQFVFFATKNGTVKKTPLGEFAFRLA--RGK---IAINLDEGD
ALVGVGLT---DGQRDILLFASNGKTVRFGED-VRSMRATGVRGIRMPAE-EVVSLIVAESVQYILTATENGYGKRTPLPDYPRKGRGTQGVIGIQTTNG
K-LVAAVLMGSRDEVLLISDGGTLVRTRGSEISRVGRNTQGVTLIRLS-KD-EKLQAVERMD--------------------------------------
------------
>tr|E7RXI9|E7RXI9_9BURK DNA gyrase subunit A OS=Lautropia mirabilis ATCC 51599 GN=gyrA PE=3 SV=1
-------HDTILCFSDRGRVYWLKVWEVPQGSRASRGRPIVNMFP-EKITVVLPIK-EHYVFMATSLGTVKKTALSDFSNPRK--AGI---IAVDLDEGD
YLIGAAVT---DGEHDVMLFSDAGKAVRFSEGDVRAMRARGVRGMALE--EGVIAMLVADD-RSVLTATENGYGKRTPLIEHTRHGRGTKGMIAIQSSNG
R-MVAAILVEEGDEIMLITTGGVLVRTRVDEIREMGRATQGVTLIGVE-EG-DTLSRVQRVV--------------------------------------
------------
>tr|U6MRN9|U6MRN9_9EIME DNA gyrase subunit A, putative OS=Eimeria necatrix GN=ENH_00001050 PE=4 SV=1
--------SYLLLVTRKGFYKRVSEASISLQSRGATGQRCFTARSSDSVAAATECRDGDWILFIWRDGRCLTLPGSHLQRHGLKTTASFVATAAAAAPAN
AVSAARTGSKEEIGGQLVVATRQGLVKALSLGLLLPTTKRTRRLLPLGLGDAVAACAVVKKDYSVVLGTAFGRALRFPCSSLPQASLLSRGVKGITLRKD
DRVVALTVVPPGDSLVVLTKKGRGKRLLLQHLSPQRRGGAGKAVLRLANREPGRLAGVWFVGPPREVGLVTERGIVSRLSVSSIPVSNKLAKGVFLQRLR
E-----------
>tr|A0A074T2L7|A0A074T2L7_HAMHA DNA gyrase/topoisomerase IV, A subunit domain-containing protein OS=Hammondia hammondi GN=HHA_221330 PE=4 SV=1
--------TQSVLLSAPALVRRLPLSVYPTLRRGALGVRSLSRAKAASLQGVWSCWTKDRLLFLSANGYVSVLPAYRVPREGWKKPATL--PAAASLAED
AVLAVPPPTKNRKAKFLLVVTDQGRIAKIKLKRIL--TRKGKKLLSLVQGDSVRAATLLEESPSIVIVTRQGMGLRFSASSLRASSSKTRGVRAIRLRAG
DSVASVAVVPPESSLLIVTAAGFGKRIRVSALRMQRRRGVGVRVIRLVKR---RVVPKKTKSDNAELLSVTQNGFLLRQSCRNIPMRGRLARGVTLQRLP
F-----------
>tr|F0V8H0|F0V8H0_NEOCL Putative DNA gyrase subunit A OS=Neospora caninum (strain Liverpool) GN=NCLIV_004870 PE=4 SV=1
--------TYRILLSSPALVRRLPLSAYPTLRRGALGLRSLARAKAPSLQGVWSCWTKDRLLFISANGYVSVVPAYLIPRDGFKKKKLALLSADVLSEED
RVLAVTPSSGKTKRRFLLVVTEQGRIAKVKLERIL--QHKFKKILAVAPNDRVRAATLLEESPSIVIVTRHGMGLRFPASSLRAASSKTRGVRAIRLRAG
DSVASVAVVPPEPSLLIVTAAGFGKRLRVSALRMQRRRGVGVRVIRLVQR---SVVAKQAKSEDRELLSVTQDGFLLRQSCEGIPMRGRLARGVTLQRLP
L-----------
>tr|I4IUI5|I4IUI5_MICAE DNA gyrase subunit A OS=Microcystis aeruginosa PCC 9701 GN=MICAK_3710001 PE=4 SV=1
-----PPENAILLLDAEDKISWTTPEQ----R----------APERGLIIYQQAIEKRENFLVILDNAKAYPIATREVPPQA--NQPVLISSLLTKAESE
AVLNQFFLTEPQKNQELLLLSQQGRIKRLPIDELEGVGSRGLSLMKLKEDDRLYGAIFTHEGLDLAIATSSGRVLRYPVRELPMMSKSAQGLAILRLRYG
EHLAGCVSLPHRENLLLISGLGYGKRLAIENLRLSQLGDLGSPALQFVN-KQDSLAAMVAARPGSIVLLSTNQNRKLPLEVETVMVTGKDGTGSQLVKLN
PTKII-------
>tr|A0A0G1S3Q8|A0A0G1S3Q8_9BACT DNA gyrase subunit A OS=Microgenomates bacterium GW2011_GWF2_46_18 GN=gyrA PE=3 SV=1
--------DYCLFFTDLGKVYAIRAFELPEGSRQAKGQAIINLEQDEKVQALLTLTKAHFVTMATQKGMVKKTPLAEYESIRTSGK-----IGISLRDND
KLVKVVLSN---GQNYIVLITALGKSIKFKETDVTATGTMGVKGMTLKPEDKVLTMETVEIFREILVVTEHGLGKRTNVEEYPEQKRGGQGVKVAELSDG
Q-VAAIRLVTEDEQVVITTKAAQVIKLPLKNIKVLGRSTQGVILMRPHP---GDVTSVTTLQKDDTIWTV------------------------------
------------
>tr|A0A0G1RJW7|A0A0G1RJW7_9BACT DNA gyrase subunit A OS=Microgenomates bacterium GW2011_GWF1_46_12 GN=gyrA PE=3 SV=1
--------DYCLFFTDLGKVYAIRAFELPEGSRQAKGQAIINLEQDEKVQALLTLTKAHFVTMATQKGMVKKTPLAEYESIRTSGK-----IGISLRDND
KLVKVVLSN---GQNYIVLITALGKSIKFKETDVTATGTMGVKGMTLKPEDKVLTMETVEIFREILVVTEHGLGKRTNVEEYPEQKRGGQGVKVAELSDG
Q-VAAIRLVTEDEQVVITTKAHQSL----------GSLNPGSYLDAPPP---GRCDQCHHPPKRRR----------------------------------
------------
>tr|A0A0G0U9A0|A0A0G0U9A0_9BACT DNA gyrase subunit A OS=Microgenomates (Daviesbacteria) bacterium GW2011_GWA2_40_9 GN=gyrA PE=3 SV=1
--------DNILFFTDKGRVFQLKVWEIPETSRIAKGQAVVNLDQGEKITAILTLRQKRYLFMCTKQGNVKKTETSQYASIRRNGL-----ISINLDSGD
TLGWVVPTN---GENELIIVSKLGQSIRFTEKNVRPTHTSGVRGVRLSKDDSVVSLNKVSDGDQLLVVMANGLGKKTLISSWNKQGRGGMGVKAAQVTNG
P-IVTAQIMDKDDTLVLTSNKGQLIKINIKDVPTLQRQTQGVILMRMRE---GEVVAATIVSQEEKG---------------------------------
------------
>tr|A0A0G0QLK3|A0A0G0QLK3_9BACT DNA gyrase subunit A OS=Microgenomates (Daviesbacteria) bacterium GW2011_GWC2_40_12 GN=gyrA PE=3 SV=1
--------DNILFFTDKGRVFQIKVWEIPETQRTAKGQAVVNLEQGEKITAVLTTRQKKYFFMCTKKGTVKKTSLEEYANIRKNGL-----TAIKLDSGD
ELGWVAATG---GKDDLIIVSKDGKSIRFTEAQVKPTHTSGVRGIRLTGKDEVVSLNTVQSEETLLVIMENGLGKKTKFSAWSRQGRGGQGVKAAQVTAG
P-IVTAQALNENDTLVMTSTKGQLIKMNLAEVPTLQRQTQGVILMRVRP---GEVAAATVVSKETT----------------------------------
------------
>tr|A0A0G1B7T5|A0A0G1B7T5_9BACT DNA topoisomerase (ATP-hydrolyzing) (Fragment) OS=Microgenomates (Daviesbacteria) bacterium GW2011_GWA2_42_7 GN=UV41_C0057G0001
--------DNILFFTDKGRVFQLKVWEIPEASRIAKGQAIVNLEQGEKITAILTIRKKKYLFMCTWQGNIKKTLIEEYASIRKNGL-----ISIKLDSGD
TLGWVMPTS---GEDDLIIVSQGGQSIRFAEKDVRPTHTSGVRGIKLGKGDSVVSLNKITDTDQLLVVMANGLGKKTLVSGWSKQGRGGMGVKAAQVTPG
P-IVTAKLASKENTLVMTSNKGQLIKLDLKDVPTLQRQTQGVILMRMRE---GEVVAATLVAKDKEP---------------------------------
------------
>tr|Q5CB96|Q5CB96_9THEM ATP-dependent Clp protease, ATPase subunit OS=Thermotoga sp. KOL6 GN=clpA PE=4 SV=1
---------STLFITNLGKAYVLKNYQIETTGRNTRGRSALNLEETEKVVALAPLNGKGDLVIVTKHGKIKRTALEEFENAT-SNRGVRA---IRIEAGD
EIISARVIDS--ERGSLVVATKLGMVIRFPVSDVRRMRAAGVQAIKLQPDDEVVSMDVVPSEGEILTVTEKGFGKRTPVELYRIQKRGGTGLRNISDKKT
GYVVAVRYVRGDEEIVVVTKNGMMIRIPVSDIGIIGRITKGVKLIELGD---------------------------------------------------
------------
>tr|A0A0K6LA48|A0A0K6LA48_BACCE DNA topoisomerase 4 subunit A OS=Bacillus cereus GN=parC_1 PE=4 SV=1
--------ETVLLFTNKGNYIYLPVYEMPDIRWKDLGQHIVSLDRDETIIWATVVPNFRFIVFVTKNGMIKKTELNQYKVQRY----SRAFVAVNLKKDD
EVVDIFATD---GTSDIVLATHGAYALIFHEDEVSPVRAAGVKAINLKEDDYVASGKPLADKDQLILVTQRGAVKRLKASEIEKSTRAKRGLVIFKEKRN
YRIVGIEIVRDDELVYMKTEKHIVEEIDPKAYRNKDRYSNGSLVLDVN--DTGEVIET------------------------------------------
------------
>tr|A0A0D7XCH6|A0A0D7XCH6_BACAM DNA gyrase subunit A (Fragment) OS=Bacillus amyloliquefaciens GN=UZ38_33700 PE=4 SV=1
--------DVLLLFTNKGSYVYCPVHQLPDIRWKDLGQHIISIDSDESIVKAIPVREFEYLLFFTKNGMAKRTQLMQYKAQRY----SKALVALNLKGDD
EVVDVHVTD---GTKDLFIATHSGYGLWFSEDEVSVVRAAGVKGVNLKDGDFVASGQ--LESDVLVLVTQRGSIKRMNRTEFEKTSRAKRGVLMLREKKK
HRITGLLACSYHAQITLQTEKGITEEMLVKDIKLHDRYSNGSFIIDED--EAGEVTDV------------------------------------------
------------
>tr|T0NXK7|T0NXK7_9BACI Uncharacterized protein OS=Geobacillus sp. A8 GN=GA8_03610 PE=4 SV=1
--------DVLLLFTRRGYYLYCPVHTLPDIRWKEVGHHLIPLERDDELVAAVPVSSFEQLIFVTKQGLVKRTELAQYQVQRY----TRPLVAVNVKEDD
DVIAVYATD---GCGHLWLATHDGHALLFAEEEISLVRAAGVKGIQLKEGDFVAAACPVLEGGSFVVVTQRGAVKKVAMSEFEPSSRAKRGVVIVREKSN
HRVVGAVFVSSEEMVGLRTEKGVVETIEAASLRLSDRYSTGSFVVDTD--EAGMVVDV------------------------------------------
------------
>tr|S2RXW2|S2RXW2_LACPA DNA topoisomerase IV subunit A (Fragment) OS=Lactobacillus paracasei subsp. paracasei Lpp126 GN=Lpp126_04633 PE=4 SV=1
--------QHLYIVTNAGNVIYRPVHEISDARWKDTGEHTVGLGTDEKVLAVFAFDQLGSFVLGSSDGYIKQTALSDLQPQRTY--KSKPMMAMKLKD-P
AAIAYFTTD---QQQDVFVVSRHAYGLTFPLSDVSTVRATGVKSMDLKPDDEVVNFIP---TAKVGILTQRGAFKKMALSEVGEMSRARRGLLVLREKRD
HRIVAMMSV--ATRLNVLTDTGKVTTLNPAQHPAGDRYSNGSFVIDTD--VLGKPVFV------------------------------------------
------------
>tr|A0A0G9GHN4|A0A0G9GHN4_LACPN Uncharacterized protein OS=Lactobacillus plantarum GN=WP50_36745 PE=4 SV=1
-----------MMFTNMGHLIYRPIYEIADAKWKDTGEHTIGLAENERITWVYSFENLGKFLVATSDGYIKQTAFADYTPGRTY--KTRASQFIKMKSDD
ATVEYLPAA---PTGTLILITQHGYGLRYDLSEVPTIKAVGVKSMDLRDDAIVRATI----DDLIAMITQRGSFKKMKVADLPVTSRARRGVQVLREKNN
HRVADYVLVASGVALDVLTDRGKHHSILNDDHPTSARYSNGSFVVDTD--TEGEPVSM------------------------------------------
------------
>tr|E1NMF9|E1NMF9_9LACO DNA topoisomerase IV subunit A domain protein OS=Lactobacillus iners LactinV 03V1-b GN=HMPREF9212_1408 PE=4 SV=1
--------SNLYIFTNKGNLIYRPVYELVDTKWRETGQHEIVLTNDERIISVFDINNLLIFLITTNDGYIKQVALSDLQPTRTY--KSRAIMVIKLKDDH
SNVEQLKSG---SDNEILLVTNSAYALRFDVNEVPLVRAAGVKSINLKNDDDYVVSAPEL-SLKLGIVTQRGAFKQLQVDLVNKFTRAKRGSMILREKTK
HRIVAALIYTQNHDINIKTSSDRTIKIRTNDYPVGDRYSNGSFVVDTI--SDGVPVAL------------------------------------------
------------
>tr|R4RWP4|R4RWP4_LACFE DNA topoisomerase IV, A subunit OS=Lactobacillus fermentum F-6 GN=LBFF_0954 PE=4 SV=1
--------SHLYMFTNQGRFIYRPVHELTDARWKDTGEHTIDLDDDEVIVKAMLLDKLGTFIFATSDGQVKQSALSDYQPGSRY--KTHASVAIKLREG-
AQVDYFEPEQ--AGQSVLAISREGYALRFAVEDVPVTRTAGVRAINLKEDDQLVGIS----GDHLGLVTQRGAFKEMAVSDLEVGARARRGNLVLHRKKN
HQVVAFVTHPATGALEIITNRPAFQDVLVAEQRLGTTQSNGSFVVDTD--TQGVPVTL------------------------------------------
------------
>tr|A0A086LWM8|A0A086LWM8_TOXGO DNA gyrase/topoisomerase IV, A subunit domain-containing protein (Fragment) OS=Toxoplasma gondii RUB GN=TGRUB_221330B PE=4 SV=1
---------NVVLLSAPALVRRLPLSVYPTLRRGALGVRSLSLAEASSLQGVWSCWTKDRLLFLSANGYVSMLPAYRVPLGSRISRGTSLPQLL-FEGGE
QVAAVLAVPPSRKAKFLVVVTDQGRIAKIKLKRILGRRCAGKEIKHLRGNDEEAGSRLVEDSPSIVIVTRQGMGLRFPASSLRASGSKTRGVRAIRLRAG
DSVASVAVVPPEPSLLIVTAAGFGKRIRVSALRMQRRRGVGVRVIRLVKRKKGYVVAVLALPDNAELLSVTQNGFLLRQSCRSIPMRGRLARGVSLQRLP
------------
>tr|D8TXP4|D8TXP4_VOLCA Putative uncharacterized protein OS=Volvox carteri GN=VOLCADRAFT_91671 PE=4 SV=1
---------------------------------------------------------ARLGDILANRTTLLAVVEQEAEAL-AAAFPEPRRTALV-AAED
VPAT-PSLELVPPKPCLVLASRRGFLRRLAGDSLTAQNRRGKSGIRLRSGDQLASLVAGSDRDLLMVVTPDGRMFKTRTAAVPPSSSSASSASPTASGGT
ESVGRMKEVEDGPCLVLCTRGGRIKRLALKNRRES-KK--GIMVMGLESSKPDEAGEEELCWPGDVVVVASAEGQVLLFPATDVRVSGPQSAGTHAMRMS
KR----------
>tr|W6W443|W6W443_9RHIZ DNA gyrase subunit A OS=Rhizobium sp. CF080 GN=gyrA PE=3 SV=1
---------------------------------------------------------SDYLDILSSRLRIQTIVKEELAAV-RDEFGTPRRTQIL-DAGL
---E-MDDELIAREDMVVTVSHLGYIKRVTLGTYRAQRRKGRSGMATRDEDFVTRLFVANTHTPVLFFSSRGIVYKEKVWRLPIGTPQSRGKALINLEPG
ERITTIMPLPENLDVMFSTTRGTVRRNKLSDFVQVNRN--GKIAMKLEEE-GDEILSVETCKPGDDVLLTTALGQCIRFPVDDVRVFGRNSIGVRGISLG
EG----------
>tr|C1N3Z1|C1N3Z1_MICPC Predicted protein OS=Micromonas pusilla (strain CCMP1545) GN=MICPUCDRAFT_52348 PE=4 SV=1
---------------------------------------------------------EQLNALLSDRALVIAAVASEAKEL-RDKYGVERKTLID-HSAA
KLKR-MNIPDSLDADNLIVMTGKGYIKRIDPKIFSRQNKIGKKGGRMRGGDQVTKVTHCNGLDTVLFFTDRGRVYAVRAYDIPQSSTTALGTPFTRLAEG
ETITAMLPVDTGEHLVMLTARGVVKKTPISEFANINRA--GKRALGLQ-K-GDRLKHVELVRDGDGIMVAGVDGMVLHFSMDSIRAQSRIGSGVKAMKFR
EA----------
>tr|E1ZRV4|E1ZRV4_CHLVA Putative uncharacterized protein OS=Chlorella variabilis GN=CHLNCDRAFT_56398 PE=4 SV=1
---------------------------------------------------------ADLQDLLQRQDRILQVVTSEAEEL-AAKFGTPRRTHII-TDGE
V--E-LRHEVIPNAPSLVVYSRRGYIKRVRPDTFGAQKRVGKAGARLKEDDSLDEVVYVNDHDHLLFFTTEGRAYSLRAYDVPEGTRTAVGSAVTQFDKS
TRIAAMVPVSGEQDVVMLTRKGQIKRTALKQFTSINRS--GLVAMGVR-E-GDSLQFVGLCSPTDSVLIAASNGSAQHFAITKLRRMGRAAVGNKSMTLS
KG----------
>tr|C1EGN9|C1EGN9_MICSR Uncharacterized protein OS=Micromonas sp. (strain RCC299 / NOUM17) GN=MICPUN_88167 PE=4 SV=1
---------------------------------------------------------EDLTGLLGDRSRVIATVAREAKEL-RDTFGVDRRTDID-TDA-
--KK-MNVTDMLNSPSLVIMTNRGYIKRIDPAVFSKQNRRGRNMGKMRGGDEVTKVTHCNGLDTVLFFTDRGRVHAVRAFNIPQASTSALGTPFTRLAEG
ESITAMLPVDTETSLCFVTARGLIKRTCASEFVGIRNN--GKKALVLR-K-GDRLKHVDIVKKGDGIIIGGIDGSVIHFDADSVRAQGRAAAGVKAMAFK
PD----------
>tr|K8F2L0|K8F2L0_9CHLO DNA gyrase subunit A OS=Bathycoccus prasinos GN=Bathy12g00470 PE=4 SV=1
---------------------------------------------------------KGNQNLLDNTSAVIDVVCEEALEV-KKKHGIPRRTTIE-TDTS
S--S-IEVEEIPNNDSLIIMSSRGYIKRTRPETFKAQRRRGKSMSKLKGSDSIAKVMHAKDLDRVFFFTDKGNVLTVRAFDIPEASTTAQGTPFTRIDKG
ESITAILSLEPETFLVMITLNGVIKKVSAKEFASIKRN--GKRAIALD-E-GDKLKQVLVAKNGDSVLVGATDGTLIRFDVDSVRKLGRMSRGVRAISLK
EI----------
>tr|E3NTF6|E3NTF6_CAERE DNA topoisomerase 2 OS=Caenorhabditis remanei GN=CRE_15839 PE=3 SV=1
---------WLLFFTNTGRVYRAKTYEVPEGGRDAKGQHLANLAPDESVTQILDLREDRFLVLATRDGLVKKTALTEYDTNR---TGGII--AIKLRDED
ELVSALIAE---SDDDVLLISKHGMSVRFTASDQALMSTSGVRGMNFRDGDQLLQASRITEGGYVFVVTEGGYAKRTAVDEYRVQNRGGFGIKVAKLDEG
DL-VGGFIVDEGDEVLAVLASGKVVRSNVAEVPAKGRNTMGVVFARFPE--RDRIIGIARN---------------------------------------
------------
>tr|A0A077ZE75|A0A077ZE75_TRITR DNA topoisomerase 2 OS=Trichuris trichiura GN=TTRE_0000613401 PE=3 SV=1
-------LDHLLILTNHGNMIYRPVHEITELKWKDVGEHISQTSMSEEIIAAFPYKENKLFIFMSKEGMIKQTRMTEFSP--WRTYRSRPTTAMKLKDTD
EIVSVFLTNET-RNVDVFIASHRAFGLRYPLEEVPVVKAAGVKAINLKDGDYVVAGAVSDGDSPILLLSQRGAAKRMLAQELPQLGRAKRGLMIFRELNP
HR-LAYMTAETEGKLTLTTTKGIEKEIEISKVAISDRISNGTFAIDEKQ--EGELFSVMQLQEL------------------------------------
------------
>tr|A0A077ZFT4|A0A077ZFT4_TRITR DNA gyrase subunit B OS=Trichuris trichiura GN=TTRE_0000757301 PE=3 SV=1
-------HDTLLFFTNSGRVYRAKGYEVPEYGRTAKGIPIINLDSNETIQAVISVGQGHFLFFVTKKGTVKRTTVTAFSN--IRANG---LIAIGLREGD
ELVNVMST--E-GDETIIIGTHDGYSVTFKEAVVRDMTASGVRGIRLRDEDYVIGSALEN--QEVLVITEKGYGKRTKASEYPVKGRGGKGIKTANVKNG
PL-AGLTTVTGDEDILLITDKGVIIRFNAGSVSQTGRATLGVRLMKMEG--NTKVVTMAIVDKE------------------------------------
------------
>tr|U5PCJ3|U5PCJ3_MESFO DNA topoisomerase 4 subunit A OS=Mesoplasma florum W37 GN=parC PE=3 SV=1
-------------------------------------------------------------AILNSEEVMDNEIINRLREVKK-QFPTPRRSTVEDSIEN
LDVE--QKEVLVEHEYNLWISKDGYLKAIESKLISK---NDPAVFGRKPNDMWIAAGEVSNLQHLILITNKGTYYSIPLYKLPMSKWRDMGVHVNTMDPN
EHIVSAFFVEALQQILITSKNGNIKRIPVKDLETKIFT--RFRIMKLDA--ADEIVSASLITSKRTCGIITRNGYGVRYHIEDIPVQGTNSKGVKAANLK
-EYIVAG-----
>tr|S6G723|S6G723_9MOLU DNA topoisomerase 4 subunit A OS=Mycoplasma yeatsii 13926 GN=parC PE=3 SV=1
-------------------------------------------------------------DILNNKEVLDQEIINRLKEVKK-TFAVERKSQVSELVEN
LDVN--QKEVLVEKEFNLWVSKDGYIKAVDNNVLAK---NDFDTFEKKPNDMWILTGVVSNLEHLILVSDKANYYSIPLYKISMSKWKDMGVHINTMSGS
ETIINAFFDNTTQQIMIVSKNGLIKRTPIVDLKTKTFN--RFKIMKLSD--DDQLVSADLVTSKRYCAIVTKNAYAVRYNIEDIPVQLTSSKGVKAANLK
-DSIVSA-----
>tr|L5L8G9|L5L8G9_9MOLU DNA topoisomerase 4 subunit A OS=Mycoplasma feriruminatoris GN=parC PE=3 SV=1
-------------------------------------------------------------LILNNNQVLDNEIISRLELVKQ-EFKVKRKSQVDDLIEN
LDVD--QKEVIVEKEINLWISKDGYIKVIDNNVLSK---NEMSLFGKKPNDMWISQGVCSNLDHLILISDQANYYSIPVYKIQQSKWKEQGVHINSTQPN
ETIINAFFTNSTQHLLLVTKNGLIKRTQISDLETKIFN--KFKIMKISD--DDSLVYADLVSSKSYCSIVTKNGYAVRYNIEDIPVQSTISKGVKAANLK
-DYIISA-----
>tr|M9WH27|M9WH27_9MOLU DNA topoisomerase 4 subunit A OS=Mycoplasma putrefaciens Mput9231 GN=parC PE=3 SV=1
-------------------------------------------------------------DILNSSQVLDQEIINRLKEVKK-EFATNRKSQVSEIVEN
LEVN--QKEVLVEKEFNLWVSKDGYLKAVDNYALAK---NELSTFGKKPNDMWISSGVVSNLEHLILVSNKANYYSIPLYKVTMSKWKDMGVHINTMDSN
ETIINVFFDSATQHVMLASRNGFIKRTPIVDLKTKIFN--RFKIMKLSG--DDELVSASLVASKRYCAIVTKKGFGVRYNIEDVPIQMTNSKGVKAANLK
-DQIVSA-----
>tr|C7LMV1|C7LMV1_MYCML DNA topoisomerase 4 subunit A OS=Mycoplasma mycoides subsp. capri str. GM12 GN=parC PE=3 SV=1
-------------------------------------------------------------EILNNNLVLDNEIISRLEEVKK-QFGIKRKSQVEDLVED
LDVD--QKEVIIEKEINLWISKDGYIKVIDNNILNK---NELSSFGKKPNDMWISQGVCSNLDHLILVSDQANYYSIPLYKIANSKWKDQGVHINSTQPN
ETIINAFFINSTQHLLLVSKNGLIKRTQISDLETKIFN--KFKIMKISD--DDSLVYADLISSKSYCCIITKNGYAVRYNIEDIPVQSTISKGVKAANLK
-DYIISA-----
>tr|W5WB66|W5WB66_9PSEU DNA topoisomerase (ATP-hydrolyzing) OS=Kutzneria albida DSM 43870 GN=KALB_5036 PE=4 SV=1
-------------------------------------------------------------KILEDESVLKKLVSSELAKVAKEFPTE-RRTILM-DGDL
KEVLSKPPLEVADDPCQVILSATGLVARTAAESEEVS--EGRRRSGRAKHDAVSAMVHSTARGRVLLVTNLGRAFKTEVLPLPVLPEQVGGMAASELEKG
ERVIGLAPLSESPGLALGTRQGVVKVCA-PEWPVR---SEEFEVIGLRE-G-DEVVGATWLTDSESLVFVSSDASLLRYAASLVRPQGLKGGGMAGINLA
LDTVF-------
>tr|A0A0K3BKA3|A0A0K3BKA3_9PSEU DNA topoisomerase (ATP-hydrolyzing) OS=Kibdelosporangium sp. MJ126-NF4 PE=4 SV=1
-------------------------------------------------------------KILDDEAVLRKVVSSELAKVAKDLTTE-RRTALI-DGDL
KEVLSKPPLEVADDPCQVILSATGLVARTAAESEESN--EARRRNGRAKHDTVAAVVHSTARGQILLVTNQGRAFKTDVLPLPVLPEASGGMAAKELEKG
EKVVGIAPLGESPGLAVGTKYGVVKVCA-PEWPVR---SDEFEVITLKD-G-DEIVGATWLKDTETVAFVSSDSSLLRFAASLVRPQGLKGGGMAGINLG
KEAVF-------
>tr|W7IJ06|W7IJ06_9PSEU DNA topoisomerase (ATP-hydrolyzing) OS=Actinokineospora spheciospongiae GN=UO65_3943 PE=4 SV=1
-------------------------------------------------------------KILDDDAVLRRVVSAELGRVAKDLTAE-RRTALI-DGDL
KEVLSKPPLEVADDPCQVILSATGLVARTAAESEESS--EARRRNGRARHDAVSAVVHSTARGQVLLVTNHGRAFKTDVLPLPVLPEQVGGMAAGELVKG
EKVVGIAPLGESPGLALGTRQGVVKVCA-PEWPVR---SDEFEVISLKP-G-DEVVGATWLGDTESLVFVSSEASLLRYAAGLVRPQGLKGGGMAGINLP
ANALF-------
>tr|K0JZB4|K0JZB4_SACES DNA topoisomerase (ATP-hydrolyzing) OS=Saccharothrix espanaensis (strain ATCC 51144 / DSM 44229 / JCM 9112 / NBRC 15066 / NRRL 
-------------------------------------------------------------KILDDDRELKKVVSGELAKVAKDLQQE-RRTVLL-DGDL
KEVLSKPPLEVADDPCQVVLSATGLVARTAAESEEAS--EARRRNGRVKHDAVAATVHTTARGQVLLVTNRGRAFKTDVLPLPVLPEQSGGMAASELDKG
ERVVGIAPLSDSPGLALGTRQGVVKVCA-PEWPVR---SDEFEVITLKE-G-DEVVGASWLGSEETLVFVSSEASLLRYSASLVRPQGLRGGGMAGITLP
GEAVF-------
>tr|A0A037UM09|A0A037UM09_SPIME DNA topoisomerase 4 subunit A OS=Spiroplasma melliferum KC3 GN=parC PE=3 SV=1
-------------------------------------------------------------AILRDINKLNSVIIHQLELIKK-KFASRRRSVIE--NEI
EAIEIQKTETIIEKDLNIWISRDGYLKALENNQLARL---ATEEFKRKPGDLWIADFQANTSDKILLITSKGNYVIIPVYKIKTVRLRDIGEHVNTLPGE
EKIISAFLLNKEQYIMLATKNGMIKKTAVKDFE-ATRISKALKAINLKN--DDEVVASQLAGHHPYVVITTANGFIVKYRKKQIPTLGLRTAGVKSINLR
DDVVINAGY---
>tr|A0A0H3XJV5|A0A0H3XJV5_9MOLU DNA topoisomerase 4 subunit A OS=Spiroplasma eriocheiris CCTCC M 207170 GN=parC PE=3 SV=1
-------------------------------------------------------------AILAEEAKLLAVIVEQLELIKN-KFPSPRKSVIE--NDI
ELIEIEKTETIIEKDVNLWVSRDGYLKALDNSQLAKI---TADEFNRKPLDLWVANFSANTLDKILLITSKGNYVIIPVYKIKMSKIKDIGEHVNTLPGE
EKIVASYLLDPNITIMIATKNGMIKKVPVLDFE-ATRISKAMKAINLKA--DDEVVASQLVKDEPYVSIFTKNGFAVKYKQQEIPSLGLRTSGVKSINLK
DDEVVGAGY---
>tr|A0A0C2E092|A0A0C2E092_9MOLU DNA topoisomerase 4 subunit A OS=Spiroplasma poulsonii GN=parC PE=3 SV=1
-------------------------------------------------------------AILSDINKLNHVIIRQLELIKK-RFHSPRRSIIE--DEI
EAIEIEKTETIIEKNLNIWISRDGYLKALENNQLVKL---TTEEFKRKPGDLWIADFQANSLDKILLITSKGNYVIIPVYKIKSVRIKDIGEHVNTLPGE
EKIISAFLLNPEQYIMLATKNGMIKKTAVKDFE-ATRISKAIKAINLKG--DDEVVASQLVDKHLYVVVTTVNGFIVKYKAKEIPALGLRTAGVKSINLR
DDTVVGAGY---
>tr|R4U401|R4U401_9MOLU DNA topoisomerase 4 subunit A OS=Spiroplasma syrphidicola EA-1 GN=parC PE=3 SV=1
-------------------------------------------------------------AILSDINKLNSVIVEQLTLIKN-KFNAPRRTFIE--EEI
ETIEIEKTETIIEKDLNIWVSYDGYIKALENNQLARL---ANEDFKRKPNDLWIADLQANTLDKLLLITSKGNYVIIPVYKIKVSKIKDIGEHVNTLPGE
EKIIGCYLLNPDNYIMLATKNGMIKKTAVPDFM-ATRISKAIRAINLKG--DDEVVNSQLVTKQPYIIIATANGFAVKYKASEIPTLGLRTAGVKAINLK
DDIVVNAGY---
>tr|R7GEX1|R7GEX1_9CLOT DNA topoisomerase IV A subunit OS=Clostridium sp. CAG:307 GN=BN598_00318 PE=4 SV=1
------------------------------------------------------------NSILNSDKKLLKVIKQELVDMKK-NIVTPRRTEIQHEISD
L--TIDEQDLIQKEQNYFVATKDGYLKRVSIKNYNL---SKL--NTIKEKDSIVFEGEVSTTDVMLGFTNLGNFVYIPIFKVDECKMKDVGSYINNISPI
EKLIRVFIISDKTNLLLTTKNGLIKQTLLNDFV-VSRYTKAVRAMKLQE--NDELISVDMTTNPLEIVCLTHECDALRFRASDVALYGTTAGGIKAIALK
PSYLVSAF----
>tr|U6MRN9|U6MRN9_9EIME DNA gyrase subunit A, putative OS=Eimeria necatrix GN=ENH_00001050 PE=4 SV=1
------------------------------------------------------------RRLLSDDAQLFTLIKEELQEIDR-KYGSPRKTLFLRKGPQ
SLETFDGEEEKDSKSYLLLVTRKGFYKRVSEASISLQSRTGQRCFTAGSSDSVAAATECRDGDWILFIWRDGRCLTLPGSHLQRHGLKTTASFVAAAAPA
NAVSAARTGSIGGQLVVATRQGLVKALSLGLLLPTKRKNRTRRLLPLGL-G-DAVAACAVVKEDYSVVLGTAFGRALRFPCSSLPQASLLSRGVKGITLR
KDRVVALTVVPP
>tr|A0A0F7UTW9|A0A0F7UTW9_TOXGO DNA gyrase subunit A, putative OS=Toxoplasma gondii VEG GN=BN1205_051980 PE=4 SV=1
------------------------------------------------------------ASLLAHDREIYELMVEELQAHKT-RHKAPRKTKVLGRAQQ
RREETEGLGGRDTSTQRVLLSAPALVRRLPLSVYPTLRRLGVRSLSRSKASSLQGVWSCWTKDRLLFLSANGYVSMLPAYRVPREGWKKPAAL--GALAE
DAVLAVPPPTKAKFLVVVTDQGRIAKIKLKRIL-RRCETKVKKLLSLVQ-G-DSIRAAALLETSPSIVIVTRQGMGLRFPASSLRASSSKTRGVRAIRLR
AGSVASVAVVPP
>tr|F0V8H0|F0V8H0_NEOCL Putative DNA gyrase subunit A OS=Neospora caninum (strain Liverpool) GN=NCLIV_004870 PE=4 SV=1
------------------------------------------------------------ASLLAHDNEIYDLMTDELKALKS-RHRAPRRTKVVWGKGR
R-SEVARVSG--TRTYRILLSSPALVRRLPLSAYPTLRRLGLRSLARSKAPSLQGVWSCWTKDRLLFISANGYVSVVPAYLIPRDGFKKKKLALLVLSEE
DRVLAVTPSSKRRFLLVVTEQGRIAKVKLERIL-QHRETKFKKILAVAP-N-DRVRAATLLETSPSIVIVTRHGMGLRFPASSLRAASSKTRGVRAIRLR
AGSVASVAVVPP