>seq_1
VQTGGFSKESILPKRNSDKLIARKKDWDPKKYGGFDSPTVAYSVLVVAKVEKGKSKKLKSVKELLGITIMERSSFEKNPIDFLEAKGYKEVKKDLIIKLP
KYSLFELENGRKRMLASAGELQKGNELALPSKYVNFLYLASHEQKQLFVEQHKHYLDEIIEQISEFSKRVILADANLDKVLSAYNKHRDKPIREQAENII
HLFTLTNLGAPAAFKYFDTTIDRKRYTSTKEVLDATLIHQSITGLYETRIDLSQ
>tr|A0A0R2N8E4|A0A0R2N8E4_9LACO Crispr-associated protein OS=Lactobacillus delbrueckii subsp. jakobsenii ZN7a-9 = DSM 26046 GN=IV58_GL001508 PE=4 SV=1
TKKSALFNQTVYPSPKRSGLIPRKRGMDPEIYGGYAHNQDSYFVL--AKIEKVK----GYTLQIVGVPIRSLEIINKAEDFSTASKTRGIKNEILVNKLP
YRQPILEKDVSYM-LGSSAYKYNVKQITLSRQSMKYILDYIHEMTQNERECLLSVYDEILEKVDKYLPLFDGNK--FREKLHSARKFVSLSVDDEASKLR
GLHSLENLKIKPALGFFQMK------NGITLSNDAVLLYQSPTGLFERRVKVS-
>tr|E3ZTQ9|E3ZTQ9_LISSE Crispr-associated protein Csn1 (Fragment) OS=Listeria seeligeri FSL N1-067 GN=NT03LS_2928 PE=4 SV=1
IQKGEFSNATANPKGNSSKLIPRKADWDPIKYGGFDGSNMAYAIV--IEHEKRKKK-TVIKKELIQINIMERTAFEKDQKEFLEGKGYRN--PKVITKIP
KYTLYECENGRRRMLGSANEAQKGNQMVLPNHLMTLLYHAKGKSL---IESHREMFAELLDSISEFASRYT-------ANLEKINTFEQNKSGDVK-QFV
NLL---AMGAPASFKYFETNIERKRYNNLKELLNATIIYQSITGLYEARKRLD-
>tr|A0A0E1Y204|A0A0E1Y204_LISMN Crispr-associated protein Csn1 (Fragment) OS=Listeria monocytogenes FSL F2-208 GN=NT04LM_3941 PE=4 SV=1
IQKGEFSKATIKPKGNSSKLIPRKENWDPMKYGGLDSPNMAYAVI--IEHAKGKKK-IVIEKKLIQINIMERKMFEKDEEAFLEEKGYRH--PKVLTKLP
KYTLYECEKGRRRMLASANEAQKGNQLVLSNHLVSLLYHAKGKSL---TEAHRETFSELLAQVSEFATRYT-------ANLSKINNFEQNKEGDIK-QFV
DLM---AMGAPASFKFFEATIDRKRYTNLKELLSSTIIYQSITGLYESRKRLD-
>tr|L2QAM9|L2QAM9_ENTFC CRISPR-associated protein cas9/csn1, subtype II/nmemi OS=Enterococcus faecium EnGen0038 GN=OKI_04697 PE=4 SV=1
IQKGGFSKETVEPKKDSSKLLPRKNNWDPAKYGGLGSPNVAYTVA--FTYEKGKA--RKRTNALEGITIMEREAFEQSPVLFLKNKGYEQ--AEIEMKLP
KYALFELENGRKRMVASNKEAQKANSFLLPEHLVTLLYHAKKESF---VNEHHKEFSEVFARVLEFAGKYT-------KNIEKLEKYKENQTDDLA-SFV
NLM---AMGAPADFKFFDVTIPRKRYTSLTEIWQSTIIHQSITGLYETRIRMG-
>tr|S2RIP9|S2RIP9_LACPA Uncharacterized protein OS=Lactobacillus paracasei subsp. paracasei Lpp126 GN=Lpp126_15364 PE=4 SV=1
FETADLFKQTVYGARGSKQLIPKKKGYPVDIYGGYFRENTAYLAV--VKVTKKT----ETIFKVVKIATSQVAALNKARSQSTAP-GITDTPEVVLPRVP
REQLFYNAKYGFFMVNSDTMFHNFQEIWVSRSDQKILQQIR--KAPNVDQDLDNLFHNLADQIVKYFDLYSIAG--FKEKISQSQNFNDLAVDDTDTELK
GAQSLKVLKISTPFGFTQDK------SGV-LTKDSSIIYQSPTGLFERSVRLT-
>tr|F3R2Q3|F3R2Q3_ENTFL CRISPR-associated protein, Csn1 family OS=Enterococcus faecalis TX1467 GN=HMPREF9520_01275 PE=4 SV=1
VQKGGFSKESIKPKGPSNKLIPVKNGLDPQKYGGFDSPIVAYTVL--FTHEKGKK--PLIKQEILGITIMEKTRFEQNRILFLEEKGFLR--PRVLMKLP
KYTLYEFPEGRRRLLASAKEAQKGNQMVLPEHLLTLLYHAKSESL---VEQHQPEFQEILERVVDFAEVHT-------SKVQQIVKFEANQTADVK-AFI
QLM---AMGAPSTFKFFQKDIERARYTSIKEIFDATIIYQSTTGLYETRRKVV-
>tr|R0EQN0|R0EQN0_PEDAC CRISPR-associated protein Cas9/Csn1, subtype II/NMEMI OS=Pediococcus acidilactici D3 GN=PAD3_0055 PE=4 SV=1
TKHGALFNQTIYSAK-SKTMIPIKNDRPTKLYGGYSGNEDAYMSI--IRLSDKK----K-TYKVVGISMRDASKLKAYENNAHEQ--KTKADEIVIPKVN
YHQRMQDGTKQFR-IGSSKYVHNTKQLVLSEKTLKAIRN----NKGDAEKDLINAFDEILTIVNDSFSIFDIRS--FRKKLNESRDFVSLPVEDTKEQLI
ALHDIPQLGLK-SFGKMVKT------GGLTLSENTVLIHQSPSGLFERKIKLS-
>tr|A0A0F7PS68|A0A0F7PS68_9LACO Uncharacterized protein OS=Lactobacillus salivarius str. Ren GN=LsR_00110 PE=4 SV=1
TKNGAFYDQTKYNAK--VNLIPIKKDKPTNIYGGYKGKVSSYMML--VKIQKKK----EIIYKFVGVPRLWTDELDRLNDTDEKK--KAEQNEVILDKVY
YGQLIIDGGQKYT-LGSSEYKYNAMQLHLSTRSLKTLAK----EKEVTDKELVDVYEEILSVVNKYFELYDISK--FRQKLNEGLEFKELPIHNVYERLI
GLHDLKVLGIKTKLGQMQVK------GGIKLSPDAKLIYQSPTGIFSRAVRVK-
>tr|A0A0C1M7A0|A0A0C1M7A0_9LACO CRISPR-associated protein, SAG0894 family OS=Lactobacillus fructivorans GN=LfDm3_0193 PE=4 SV=1
TNHGALYKQTVFPSPKSRKLINAKKDRPTDIYGGYSAQTNGFMAL--VKIAKPH----GDEYRLYGIPLMEYNQLKDNEAGKFDE--GKMPERVVLYKVD
INQLVKDDHTIYT-VSSKAYKQSAQQLVLSDGSMRTLTN----NYNVGRDDLIETFNEIIDNTIKFMNMYDIND--PEKIKS----FTKLS-----NNLI
SLHDVSGIGMSKWFGLFQLK------AGLKLSLKDELIYQSPTGLFSRKVRIS-
>tr|A0A099YDU3|A0A099YDU3_9LACO Uncharacterized protein OS=Lactobacillus mucosae GN=LX03_06640 PE=4 SV=1
EFRGALFDATKVSHLATDKFIPLKKGLPTTIYGGYAKSNMGFMTI--LRVEPSQRQ-KPAYLRVLGIRRIDSDRINQLLAANRRAKGERQSRTVVVPKVL
HGQEVKTLAGSYQ-MSSFKYKRSSSQLILTPQTRWELYQAM--AGEQAERVLLRAYDEVLSQLDHFTLFMQQPA--PAERLKAYQQFEQLPLRNGLTNLM
SLHTLTGRPIIKNFGLFST-------TAISLPIGTKLWFSSPTGLHRSYKSLG-
>tr|C2KFJ4|C2KFJ4_9LACO Uncharacterized protein (Fragment) OS=Lactobacillus crispatus JV-V01 GN=HMPREF0506_1619 PE=4 SV=1
-KNQEMFGMTIYPRAERRKLIEKRKGFSTDIYGGYTGTAAAYMAIVRINKTKSS------QYKVIAVPMTKRAIAEKEGNYELKQILSPSIKDIIKGKVP
YNQVVQD-GNKKFLLKSAIYLCNAKQLVLSEEAMRVITGHWDKQDQ---EL-LDVYDEILEKIDRYLPLFDI-RDFRNKLHKGREKFLKLNKFKAIIQIL
KGLHDNSDTGELKDIITVPFGQLQNNSGITLSSDTILVYQSPTGLFEKRVKISS
>tr|A0A0R1GFV6|A0A0R1GFV6_9LACO Uncharacterized protein OS=Lactobacillus parabrevis ATCC 53295 GN=FD07_GL002250 PE=4 SV=1
-DNGELFQQTIQAAKEGNTLIRHKKDMPTELYGGHIGSSDAYMCILRVFEKKEV------TYWVMRVSKLELGKLEKNGLSELHELFLSEV-EVVLPHVY
LQQTVRDEINGTFGLSVAKSISNHQQLYLSYDTQ-------EEDKV---TD-RDVYSSILKQFQEYYPLMWG-KDNLKNMSDSEEKFDELSRIETLKKIM
RGMHAGTEFAKLKYFLGDEFGRIRPNKGAVLTDKASLIFQSPTGLFTRQIFLKN
>tr|A0A0J6X8W2|A0A0J6X8W2_LACRH CRISPR-associated protein (Fragment) OS=Lactobacillus rhamnosus GN=PZ01_12735 PE=4 SV=1
-ETADLFDQTIYAAKDSMSLIPKKLGYLTGIYGGYQTERGSYVSIIRTFKKGET------IYKVVNILTADVSLKEKV---SLADIYLKELGEIVLPRVG
KDSLFKNKKYGLFLIESATELHNYQELWLPRND--------SKADY---EL-TRMYRNIAWQVDHYFRLYKI-RKFAEKLQASVEDFAGLPKVEVLASVL
KRLNGAADKGRTNPTVKSDFGRTLLTNGIVLEDDSSIVYQSPTGLFKRSVKLVD
>tr|F0K1W6|F0K1W6_LACD2 Hypothetical conserved protein OS=Lactobacillus delbrueckii subsp. bulgaricus (strain 2038) GN=LBU_0746 PE=4 SV=1
-KKSALFDQTVYPSPERSGLIPRKKGMDTEIYGGYSGNKDAYFVLAEAVKEKGH------TLQIVGVPIRAL--LKNSANYSLLEIIKPQVIKILMDKIP
CRQPVLE-GESYYMLASSKYRYSLKQISLSQMSMKYILDYIQDEKE---CL-LSVYDEILEKMDKYLPLFDI-RSFRKKLHDGRDAFIALPEVDVIRKIL
KGLHANADITNLAELFGAALGALVSTGGIKISDDAVFIYQSPTGLFERRVKVSD
>tr|A0A062XPB2|A0A062XPB2_LEUPS CRISPR-associated protein, Csn1 family OS=Leuconostoc pseudomesenteroides PS12 GN=L965_580 PE=4 SV=1
-NKGAMYDANLISAKGSKAQLQISKSKNIDLYGGFNKLQNEYSVLILNHDE----------YGWLSIPMYARNS-------SLHDKYPDAK--VILNHIL
VGQPILLSNSSKSKFASGGDYHNNFEFVPSVDVKKILDNIYSVTDD---EY-KKVFESLLATLDKFV--FGI-HQVYNKIFDNKYLFDKMPKRNVINSLL
KFMNISKNQLGA-VGIGVLYGTEKLISNGKMQPHDIFIFQSPTGIFERRVTVAE
>tr|W7CWL2|W7CWL2_9LIST CRISPR-associated protein, Csn1 family OS=Brochothrix campestris FSL F6-1037 GN=BCAMP_03945 PE=4 SV=1
-QSGMLFKETIYPALK-IPL---KKNLGVSLYGGYTNVNYAFYSLIEYPVKNKQ------KRRLLGIPMATKVLIDTGQTTLVTDC-IGGP--ILKERVL
KYQLIQNDNCALYVAGP--ERHNARQLVVSEAAAQIIYLISQYRS--------------SDLTVVFDELLLK-ITSKLTA--AAERFNVCTKVIIIEEII
KVMRANAT--NGN--LKGLTEREGRLGNVPISNNLKIINQSITGLYQSIEDFS-
>tr|A0A0R1KBP1|A0A0R1KBP1_9LACO Uncharacterized protein OS=Lactobacillus nodensis DSM 19682 = JCM 14932 = NBRC 107160 GN=FD03_GL001175 PE=4 SV=1
-YDGALYNELIRKHDPKIPL---KKGIDPTIYGGYTSDKPSYSTLVNLDGK----------KKLVNIPVRIAHEIDAGRINKIYDNTK---KEILIDKVP
IGQIVESSARGYVSLPSATELINAKQLILSYEETALLSILKNYSPN---YL-STIYKNIISKMKLYYPLYSN-EAK---------------QFNVLIEIL
NLLHADSSNARLEFGIKEY----GRKHREFEFSNSDFIYQSPTGLYESRIHID-
>tr|F5VWH3|F5VWH3_STROR CRISPR-associated protein Cas9/Csn1, subtype II/NMEMI-like protein OS=Streptococcus oralis SK255 GN=HMPREF9968_0493 PE=4 SV=1
-KKGAFYNQNP--VGKFYPLKTKVSSLDTSIYGGYGPMNSALSIIIIAERFNEKKCKIETVKEFHDIFIIDYKKFNNDP--FLNDTSENGFKVLAFYRVP
KYSLMQKIDGTRMLFES--NLHKATQFKLTKTQNELFFHMRHKEEF---DN-------ISNQLSAFSQKMLG-D--RKIKEINSSEETIKY-----DNFI
KMFSFVKSGAPKDINFFKYTVARMRPKPDKKLLNATLIHQSITGLYETRIDLSK
>tr|F5U993|F5U993_STREQ Uncharacterized protein (Fragment) OS=Streptococcus dysgalactiae subsp. equisimilis SK1249 GN=HMPREF9964_0649 PE=4 SV=1
-QTGALTNESIYARGSF-----RKHRFESSKYGGFGSPTVTYSVLVVAKSKDGKVKKIKTGKELIGITLLDKLVFEKNP--LIEDKGYGNV-IDKCIRLP
KYSLFEFENGTRRMLASRGDLQKANEMFLPAKLVTLLYHAHHYNDL---YQ-------LLSYIERFASLYVD-VEK----------YSISE-----SSVI
NLLTLTASGAPADFK--GTTIPRKRYGSPQSILSSTLIHQSITGLYETRIDLSQ
>tr|E9S0G4|E9S0G4_TREDN Uncharacterized protein OS=Treponema denticola F0402 GN=HMPREF9353_00242 PE=4 SV=1
-KKGGLFDQTIMKKGLGHPLKKEGPFSNISKYGGYNKVSAAYYTLIEYEEKENK------IRSLETIPLYLVKDIQKSQEKLLTDLLG---KKILVPKIK
INSLLK-INGFPCHI--SFLLRPAVQFCCSNDEVLYFKKIITKNDE---IG-EKEFYDLLKNLEIYDMLLTK-HKDLGMLTKGRYEFINLKQIIVMLEIL
KLFCTTREAIDL--GIKPAAGVATLGKKISNLDNCILIYQSITGIFEKRIDLLK
>tr|E7NSW3|E7NSW3_TREPH Uncharacterized protein OS=Treponema phagedenis F0421 GN=HMPREF9554_01153 PE=4 SV=1
-KTGGFFDQNIMKKGKGFPLKENSPLSDISKYGGYNKVSGAYFILVQKKEKDAV------VRILETVPLYLLNKPGKESENVLSTALG---TKILIPKIK
INSLFK-INGFLVHI--RFLVRSAVQFFCDDNLTLFFKRII-KNQL---FD-KNKFNEIVKNISVYKDMVKR-YETIPILKSGEDKFINLPQFKILQEIL
KLFGAINGTANL--TIGPSTGEMKISNNISNLKQCILIHQSPTGVFEQQIDLLK
>tr|A0A0R1QGB6|A0A0R1QGB6_9LACO CRISPR associated protein OS=Lactobacillus mindensis DSM 14500 GN=FD29_GL000796 PE=4 SV=1
-ANGEFYNQTVYKKDEKRKLISLKQ-GDTKLYGGYSGDNPAYIVLVKI--DDKK-------NKLVKMPIRLAEQVDNKTITWLEVPHKKGIQ-VLKTKIP
LGQVIYSKKNGYLALKSDTEIVNAQQLVLPYGYVALLTLLQKMPENYDDGILDNIFVAIIDKMKHFY---PYYSGELKTLSDNIDNFKESPDVNKIKTLQ
QLLLLLHASSTTSIEN-VKKNSLGRKPNSINIQNTDLLSFSATGLYESRIHID-
>tr|A0A0R1SCA3|A0A0R1SCA3_9LACO Uncharacterized protein OS=Lactobacillus versmoldensis DSM 14857 = KCTC 3814 GN=FC27_GL002053 PE=4 SV=1
-QHGKLFNDTIQPHSDRYKLIPLKT-NDPAIYGGYNNDNNAYSVVLDV--DGKK--------KINGIPIRIANQLKSDELSWLEIKHKKPMT-ILIDKVP
KYQRIINEETGDLLITSANEVINNVQLFLPSMYTALISLLDSTKTEYEANILIDIYDYLLTKLKNNY---PLYRKEWAKLAEHRDDFIESDLVTQASTLQ
QLIKFMHADPSNNLKN-FKGNRFGRKNGNIKLSKTDFIYESPTGLFKSIKHID-
>tr|A0A0H4LAX2|A0A0H4LAX2_9LACO CRISPR-associated endonuclease Cas9 OS=Lactobacillus farciminis GN=cas9 PE=3 SV=1
-KTGQFYDQTIYSPKKYKKLIAQKK-DDPNIYGGFSGDNKSSITIVKI--DNNK-------IKPVAIPIRLINDLKD-KKNWLEVKHKKSIQ-IIKNNVP
IGQIIYSKKVGLLSLNSDREIANRQQLILPPEHSALLRILQ-IPDEYDKNILVEILQELITKMKKFY---PFYKNEQEFLASNIENFNQATTSEKINSLE
ELITLLHANSTSHLIN-IEKKAFGRKTHGLTLNDTDFIYQSVTGLYETRIHIE-
>tr|A0A0K2LF21|A0A0K2LF21_9LACO CRISPR-associated endonuclease Cas9 OS=Lactobacillus heilongjiangensis GN=cas9 PE=3 SV=1
-KTGEFYKQTLYSPHNVKNPIPQKK-NDPKIYGGYSGVQSSYLAIIKV--DQKK-------PTMVSVPIRFSKMIDDGKLSWLEIKHKKTIE-VLKTKIP
IGQLTYNPKNGYLSVQSEKEIANAQQLFLPFEHVALLTLLH-APTSYDTDILLEIFDEITNKIKTFF---PFYIDEQEYLVSIRENFQSATVIEKVNVLQ
QLLIMLHANSSRSIKE-VSKKDLGRKKKRIPLENTDLVYQSVTGLYQTKFHID-
>tr|A0A0R2FVI8|A0A0R2FVI8_9LACT CRISPR associated protein OS=Weissella halotolerans DSM 20190 GN=IV68_GL000750 PE=4 SV=1
-PEGALYKETLIAADK-KRLVGASKERDPTIYGGYTKESSAYMSLVRA--GGKNQ--------LVKIPVRIANEIHSGQRDYVQAKVKKFER-ILLPKIS
LGQLVED-EGQRFYLATNEMKHNAKQLWLDQKVVTTYKRLTESPVE-----------DALTATIHHF---KFYQRDLELLRDNRAGFQDLAKATQLKVLK
DVLYELHDNAGWPIKIGLKVRMWTKLQKIKLTDQAELIYQSPSGLFEKRRRVQ-
>tr|A0A062XBE5|A0A062XBE5_9LACO CRISPR-associated endonuclease Cas9 OS=Lactobacillus animalis GN=cas9 PE=3 SV=1
-QTGGFSDEMLVP--DSGKLLPRKEGL-PVKYGGYAKAVESYAVLITADEV-KKGKT-KKVKTLVNIPIIDSKKYEADPTAYLASRGYTNVT-NS-FILP
KYSLLEDPEGRRRYLAS----FKANELILPQHLVELLYWVNKD---KLEAEFKELFDKIME---DKY---VVAP-NSEKIRR---LYEENTPMELGKN--
ELLRYTADGAAS-FKFFGENI--KRYN-AGSLLNGTLIYQSKTGLYETRIDLG-
>tr|A0A0R1TV35|A0A0R1TV35_9LACO Uncharacterized protein OS=Lactobacillus apodemi DSM 16634 = JCM 16172 GN=FC32_GL001344 PE=4 SV=1
-QTGSFYDETVAK--ASQKLFPRKNGL-PVKYGGYQRANEGYSLLFRADMLNKRGKT-KSVKTLVKIPIIESAQYLADPTEYLAKRGYYNVSEHS-LLLP
KFSLLENNNGLRRYLAS----SNANELILPKHLVRLLYWSQKQ---ELNAEFAELFTYIMD---DKY---VVAP-NSEKIKN---IYENNSVEVLGKN--
ELLKYTADGAAS-FTFFDTKI--KRYN-AGDLLDGTLIYQSKTGLYETRIDLG-
>tr|A0A0K8MQR7|A0A0K8MQR7_9LACT CRISPR-associated endonuclease Cas9 OS=Fructobacillus pseudoficulneus GN=cas9 PE=4 SV=1
-DDGALNKETIYGVDK-AKLIGTNKQRDVSLYGGYTYPYSAYMTLVRA--NGKNL--------LVKVSIAAAKKIESGQIEYVKPEVKKFEK-VLIKMIP
IGQLVLN-DEKLMYLVSYEFYHNAKQLWLPSKEADFISQLTDSVDD-----------DLLTKVLKRF---PFYAQDLQKLIFLRESFKFIDN--KYEVLE
TILKGLQLDAAQPVKIDKTAVDWKNYRQIKLSDNAEIIYQSTTGIFEKRVKIA-
>tr|A0A0K8MIK7|A0A0K8MIK7_9LACT CRISPR-associated endonuclease Cas9 OS=Fructobacillus ficulneus GN=cas9 PE=3 SV=1
-DRGPLSKETIYAVDK-AKLIGTNKHRDVSLYGGYTYPYSAYMTLVRA--NGKNQ--------LVKVSRSAASLMKSGQLDYVQPEVKKFEK-ILLEHLP
LGQLVDN-DGKLMYLTSYEFYHNAKQLWLSTENADLISSLSDSDDQ-----------DILTSVIERF---PFYEIDLKKLIELRDKFVLIDN--KLDVLR
VVLKALQLDSAQPLKIDKAATDWKNYRQIKLSDNAEIIYQSTTGIFEKRIKIS-
>tr|A0A0J5P9G6|A0A0J5P9G6_9LACT CRISPR-associated endonuclease Cas9 OS=Fructobacillus sp. EFB-N1 GN=cas9-2 PE=3 SV=1
-DNGALNKETIYAVDK-AKLIGTNKKRDVSLYGGYIYPYSAYMTLVRA--NGKNL--------LVKVTISAAEKIKSGQIEYVQPEVKKFEK-ILINKLA
IGQLVNN-DGNLIYLTSYEFYHNAKQLWLPTEEADLISQLNDSSDE-----------DILTAILKRF---PFYELDLKKLVNIRDKFIAVEN--KFDILM
VILKALQLDAAQPVKIDKKSADWKDYRQIKLSDTSEIIYQSTTGIFEKRVKIS-
>tr|A0A0K8MM86|A0A0K8MM86_9LACT CRISPR-associated endonuclease Cas9 OS=Fructobacillus fructosus GN=cas9 PE=3 SV=1
-DRGPLNKETIFSPKG-KKLIPLNSKRDTALYGGYSNVYSAYMTLVRA--NGKNL--------LIKIPISIANQIEVGNLDYIVPAIKKFEK-ILISKLP
LGQLVNE-DGNLIYLASNEYRHNAKQLWLSTTDADKIASISNSSDE-----------DILTNVKNRF---PFFKKDIDKLSQVRDEFLDSDK--RIAVIQ
TILRGLQIDAAYPVKISKKVSDWHKLQQIKLSDNSEMIYQSATGIFETRVKIS-
>tr|R6QHH1|R6QHH1_9FIRM CRISPR-associated endonuclease Cas9 OS=Eubacterium sp. CAG:251 GN=cas9 PE=3 SV=1
-KKGGLFKVTIL--K---GQASIKKNRSIEKYGGYNQVSSTYFSCVEH--GKDNNR----MISMFSVNLYDKNKYEENPIAYLI-----NPI-IKVKKVK
IQSCISFD-NMLCHLGGKDSGQIGVQLVLGYDNERYIRNVICAGGDVTAEKNIELFNLLIE-IYGVL---YSN--LGDKLYCSKEKFEKLDIVEQCNVIK
NVLTILKNNAS-DLKSIGIKA-NGAIRLISEVKSIKLINQSVTGLFEQEIELL-
>tr|R6U7U5|R6U7U5_9CLOT CRISPR-associated endonuclease Cas9 OS=Clostridium sp. CAG:964 GN=cas9 PE=3 SV=1
-KKGGLFKIQPL--K---GQAPLKKDLDIGKYGGYDKPTASYFSYIKY--EGKKGK---ECRQLVAIDNYLKKYYEENPIEYLT-----NPA-VLIPVIK
YNSCIEID-GFRMNISSKSNETIAVQLVLGAEKEAYVKKISVLSKPVSAEENIELFDALTA-IFKIK---LED--IGNKIKSGRDKFVTLDVKKQCYVIN
EILKIMHCNVV-DLSLIGAAKKAGIVSTLSEVSSIMLINQSVTGLFETKIDLL-
>tr|E7MR72|E7MR72_9FIRM CRISPR-associated endonuclease Cas9 OS=Solobacterium moorei F0204 GN=csn1 PE=3 SV=1
-VKGELFDQQIV--P---GQFPIKQG-DIEKYGGYNKLSSAFLFAVEY--KGKKAR----ERSLETVYIKDVELYLQDPIKYCE-----EPQ-IIKPKIL
MGSLFSIN-NK--KLVVTGRSQYIYQLSINDEDSQYLKNIAYLQEEITSVNNIKLFDVLCT-TYEII---LNS--LKNDVNEGREKFSELDILEQCNILL
QLLKAFKCNRE-NLEKLNNKKQAGVIVIFT-CSVFKVIHQSITGLFEKEMDLL-
>tr|R3WHR8|R3WHR8_9ENTE CRISPR-associated endonuclease Cas9 OS=Enterococcus phoeniculicola ATCC BAA-412 GN=cas9 PE=3 SV=1
-QTGSFSKETIKP--DSDKLISRKTNW-PKLYGGFDSPQVAYSVIITYE--KGKKKV--RAKAIVGITIMEQSLFKKDPVSLLEEKGYANPE--VLIHLP
KYTLYELENGRRRLLAS----ANGNQLVLPASLVTLLYHAKVDED-YVRAEFAEILNYVQA---ETK---ILAN-NLQTILK---LYEENDIKEIAES--
NLMKFSAYGAPM-FKFFGKTI--SRYT-VGELLSATIINQSITGLYETRRKLV-
>tr|A0A0H3GNI1|A0A0H3GNI1_LISM4 CRISPR-associated endonuclease Cas9 OS=Listeria monocytogenes serotype 1/2a (strain 10403S) GN=cas9 PE=3 SV=1
-QKGEFSKATIKP--NSSKLIPRKENW-PMKYGGLDSPNMAYAVIIEHA--KGKKKL-IFEKKIIRITIMERKMFEKDEEAFLEEKGYRHPK--VLTKLP
KYTLYECEKGRRRMLAS----ANGNQLVLSNHLVSLLYHAKCEAS-YIEETFSELLAQVSE---TRY---TLAD-NLSKINN---LFEQNDIQAIAQS--
DLMAFNAMGAPA-FKFFEATI--KRYT-LKELLSSTIIYQSITGLYESRKRLD-
>tr|A0A097B8A9|A0A097B8A9_LISIV CRISPR-associated endonuclease Cas9 OS=Listeria ivanovii subsp. londoniensis GN=cas9 PE=3 SV=1
-QKGEFSNATVNP--NSSKLISRKADW-PIKYGGFDGSNMAYSIVIEYE--KRKKKT-VIKKELIQINIMERVAFEKDQKAFLEEKGYYSPK--VLTKIP
KYTLYECENGRRRMLGS----ANGNQMVLPNHLMTLLYHAKCEAN-YIEEMFAELLAYISE---KRY---TLAN-RLEKINM---FFEQNDIKVIAKS--
KLKVFNAFGAPR-FEFFETTI--KRYY-IKELLNATIIYQSITGLYEARKRLE-
>tr|A0A0F5ZHG0|A0A0F5ZHG0_LISSE CRISPR-associated endonuclease Cas9 OS=Listeria seeligeri GN=cas9 PE=3 SV=1
-QKGEFSNATANP--NSSKLIPRKADW-PIKYGGFDGSNMAYAIVIEHE--KRKKKT-VIKKELIQINIMERTAFEKDQKEFLEGKGYRNPK--VITKIP
KYTLYECENGRRRMLGS----ANGNQMVLPNHLMTLLYHAKCEAS-YIEEMFAELLDSISE---SRY---TLAD-NLEKINT---IFEQNDVKVIAQS--
NLLEFNAMGAPA-FKYFETNI--KRYN-LKELLNATIIYQSITGLYEARKRLD-
>tr|A0A095XEU7|A0A095XEU7_9FIRM CRISPR-associated endonuclease Cas9 OS=Tissierellia bacterium S5-A11 GN=cas9 PE=3 SV=1
-GKGRLFKETINSRPKTEKRIPIKNNL-PNIYGGYIEEKMAYYIAINYL--ENGKT----KKAIVGISIKDKKDFEGQTTEYLGKIGFNKAS--IINSFK
NYTLFELENGSRRMIVGKENDKGGNQMYLPQNLLEFVYHLKYNED-FIVAYFDELLNYIVE---NKY---LELE-SIEKIKD---LYHGKEEKELVES--
NLLAITKCGPAA-ITFLGEKI--KRYR-TNCLWGSEVIFQSPTGLYETRLRLE-
>tr|H3NFH0|H3NFH0_9LACT CRISPR-associated endonuclease Cas9 OS=Dolosigranulum pigrum ATCC 51524 GN=cas9 PE=3 SV=1
-QKGQLWKETIYP--DSSKLIPVKEGM-PQKYGGLSQVSEAFAVVITHE--KGKKKQ--LKSDLISIPIVDQKAYEQHPTAYLEEAGYNNPT--VLHELF
KYQLFELEDGSRRMIAS----AKGNQMVLPLELVELLYHANYDKVKYVHAKFDDLLEYVID---NKY---INAD-NVQKIQK---IYKEHDVELTVES--
NLMTFTAMGAPA-FKFYGESI--SRYT-ITEFRGSTLIFQSITGLYETRYKLE-
>tr|U6S081|U6S081_ENTFL CRISPR-associated endonuclease Cas9 OS=Enterococcus faecalis VC1B-1 GN=cas9 PE=3 SV=1
-QKGGFSKESIKP--PSNKLIPVKNGL-PQKYGGFDSPIVAYTVLFTHE--KGKKPL--IKQEILGITIMEKTRFEQNPILFLEEKGFLRPR--VLMKLP
KYTLYQFPEGRRRLLAS----AKGNQMVLPEHLLTLLYHAKCLLPNYVEPEFQEILERVVD---EVH---TLAK-KVQQIVK---LFEANDVKEIAAS--
QLMQFNAMGAPS-FKFFQKDI--ARYT-IKEIFDATIIYQSTTGLYETRRKVV-
>tr|S0RVL7|S0RVL7_9ENTE CRISPR-associated endonuclease Cas9 OS=Enterococcus durans ATCC 6056 GN=cas9 PE=3 SV=1
-QTGGFYKETVNP--KPDKLIQRKAGW-VSKYGGFGSPVVAYAVAFIYE--KGKARK--KAKAIEGITIMKQSLFEQDPIGFLSNKGYSNVT--KFIKLS
KYTLYELENGRRRMVAS----HKANSFILPEKLVTLLFYAQYDEIAYVNSEFREILDQVID---NRY---TIAA-NTEKIAE---LFEQNTVQSLSQS--
NLMQLNAMGAPA-FKFFDVII--KRYP-LTEIWESTIIYQSITGLRETRTRMA-
>tr|H1GG18|H1GG18_LISIO CRISPR-associated endonuclease Cas9 OS=Listeria innocua ATCC 33091 GN=cas9 PE=3 SV=1
-QKGEFSKATIKP--NSSKLISRKTNW-PMKYGGLDSPNMAYAVVIEYA--KGKNKL-VFEKKIIRVTIMERKAFEKDEKAFLEEQGYRQPK--VLAKLP
KYTLYECEEGRRRMLAS----ANGNQQVLPNHLVTLLHHVACEVS-YIEEMFAELLAHVSE---KRY---TLAE-NLNKINQ---LFEQNDIKAIAQS--
DLMAFNAMGAPA-FKFFETTI--KRYN-LKELLNSTIIYQSITGLYESRKRLD-
>tr|C9BHR2|C9BHR2_ENTFC CRISPR-associated endonuclease Cas9 OS=Enterococcus faecium 1,141,733 GN=cas9 PE=3 SV=1
-QKGGFSKETVEP--DSSKLLPRKNNW-PAKYGGLGSPNVAYTVAFTYE--KGKARK--RTNALEGITIMEREAFEQSPVLFLKNKGYEQAE--IEMKLP
KYALFELENGRKRMVAS----NKANSFLLPEHLVTLLYHAKYDEISYVNKEFSEVFARVLE---GKY---TLAE-NIEKLEK---IYKENDLAKLASS--
NLMQFNAMGAPA-FKFFDVTI--KRYT-LTEIWQSTIIHQSITGLYETRIRMG-
>tr|R2SDC4|R2SDC4_9ENTE CRISPR-associated endonuclease Cas9 OS=Enterococcus villorum ATCC 700913 GN=cas9 PE=3 SV=1
-QTGSFYKETVNT--KPDKLIKRKNNW-VTKYGGFGSPVVAYAVVFTYE--KGKNHK--KAKAIEGITIMEQALFEKDPISFLIEKGYSNVN--QFIKLP
KYTLFELANGQRRMLAS----HQANSFILPEKLVTLLYHANYDEIAYVNSNFQDILDKVII---EKY---TSAP-KLNQIIA---TYEKNDRKIMAHS--
NLMQFNALGAPA-FKFFDTTI--KRYT-LTEIWQSTIIYQSVTGLYETRRRMA-
>tr|R7KBA0|R7KBA0_9CLOT CRISPR-associated endonuclease Cas9 OS=Clostridium sp. CAG:451 GN=cas9 PE=3 SV=1
-RTGQFYKETIYKKG---GTIPIKF-GPTDIYGGYSNTNARKLMLIEY--NESK-------MKIIGLPMALAVRNNDAE-DYIKLKKNSTFK-IKKCSIP
FETEIIYNNQNVFIK----------GYSIGHKNCEISNAIQKIAKDFAEKYVNEIYDFLIN--LDLF---PLFNKELDKIKNKVN-FEDLALDQQKKITK
ELFKMLHCNSVN---EFGLGDRMGRLSGNIT--DGIIISKSVTGIRESRYEF--
>tr|A0A0M5MAN7|A0A0M5MAN7_STRIT CRISPR-associated endonuclease Cas9 OS=Streptococcus intermedius GN=cas9 PE=3 SV=1
-QTGGF--ESILP--N-SDKLIKKFYW-TKKYGGFDSPIVAYSILVIANI--EKGKSKKLVKDLVGITIMERTIFEKNPVAFLERKGYRNVQEENIVKLP
KYSLFELENGRRRLLAS-----RGNEIVLPNHLGTMLYHAKIHKVDYVKDEFKELLDVVSN---KKN---ILAE-NLEKIEE---LYAQNDITELASS--
NLLTFTAIGAPA-FKFFDNNIDR--YTS---ILNATLIHQSITGLYETRIDLS-
>tr|R6XMN7|R6XMN7_9FIRM CRISPR-associated endonuclease Cas9 OS=Firmicutes bacterium CAG:345 GN=cas9 PE=3 SV=1
-DSGKFYKETIFKKSKETGLIPLHTK-DTKKYGGYSQLSQSYIIAVEY--KLKNKT----VKKLCRVPTLYLKQYKNDLNKIMIDEKATDIK-VLR-KIY
LNQKIRYN-GCYYLIYTSKEKQNAYQNYLDNDYLIYLNKCLKIDE-IDKNHNLEIFKSIKETIYDYT---PYIVQSRE---MKEEDFNNLSLKKQIDTLL
NMIKILSRSNEQKFEAFFENFTKVFLKT-ITNEKVYIVNESPSGLFKGKEELI-
>tr|R5V4T4|R5V4T4_9FIRM CRISPR-associated endonuclease Cas9 OS=Firmicutes bacterium CAG:631 GN=cas9 PE=3 SV=1
-FSGEFYGQTRLPKGENLIPITLNED-DTSKYGGYTNLAQAYLFAVSY--QEDGEM----KKAILRVPYLYDTLYKNDSDSKVLNPKATNIQ-ILR-KIH
LNQKIRFN-DGIYLLYTNEKDRNAYQNYIDNDYLYYLHWANHLEE-VSKAKNKEIFQYLLQKVYDTC---NYIVKARE---TNIEIFEQLTLKEQITMIN
QWIKMMSRDCEKKFDRF-TNFSNCLLRLINPKDSITIIYESPTGLFKHEVKI--
>tr|U2SSY7|U2SSY7_9FUSO CRISPR-associated endonuclease Cas9 OS=Leptotrichia sp. oral taxon 215 str. W9775 GN=cas9 PE=3 SV=1
-QKGGFSDQNIS--S---KLRPLKSSVSNIKYGGYDKIKNSYFFIVEY--T-EKKK---RVRSIETLPIYIKKSISTKEDKYCK------PK-VLVSKLN
YKSLIYSN-GHEYYINSKTAD-IGIQIILTKENYETYRKIYNLEYLEISEKFWKLYKEIFE-IFSKF---KST--LPIYIEDKLKDFTTLNNYAKSRFIQ
EILKCLNSQQG-DTKYTHNYSKKYNTKLKILENDFYIINQSPTGLFEKKVFLD-
>tr|H3NQF8|H3NQF8_9FIRM CRISPR-associated endonuclease Cas9 OS=Helcococcus kunzii ATCC 51366 GN=cas9 PE=3 SV=1
-QTGQLFDQNIIGKK---SYVPIKGDLDISKYGGYRGISGAYFFIVEH--T-EKNK---RVKTIESLPIYM--KSYVEENDFCT------PK-IIVKKLN
YKSEIIVD-GFKYLISGKTE-RLNEYLYWNHTQTTDIKKILINEKIDIEENIIKYIQIILE-PFIKR---RNL----PNIEI---NFADYETEKLLQLLV
NLIPLTTKYV-SDLTVISGSKYAGKVLIISNLNEVIFISKSITGIYESRRRII-
>tr|B0RZQ7|B0RZQ7_FINM2 CRISPR-associated endonuclease Cas9 OS=Finegoldia magna (strain ATCC 29328) GN=cas9 PE=3 SV=1
-KKGELFNATIAGKK---IYLPLKKDLDVSKYGGYKAINGAFFFLVEH--T-KSKK---RIRSIELFPLHLLSKFYEDKNDYAI------PK-IIIDKIN
YRTEIIID-NFSYLISTKSNDSINEQMYWRVDEISNLKKIEKYKKDLTEKIMESYIDKIYQ-KYKNR---RTT----DTIIEEIIDLDTLDNKQLYQLLV
AFISLSYKTSNNDFTVIGLGTECGKPRITNLPDNTYLVYKSITGIYEKRIRIK-
>tr|S1NSG8|S1NSG8_9ENTE CRISPR-associated endonuclease Cas9 OS=Enterococcus columbae DSM 7374 = ATCC 51263 GN=cas9 PE=3 SV=1
-VDGQLFDQQLM--K---GQVPIKSSLDISKYGGYNKAKGAYFVFIKS--V-RRGK---TIKSFEYIPVHLAKKFDCNLEEYLE------VE-ILMPKVM
INSLFNYN-GSLIRIPGRYDKSLDVPLLLESQHIKQLKVIEYMYKKDQLKDLDALFDVLSY-IYNVI---ND---YD-KLVICRDKFISLDTEVKCEMIF
ELLHLFQCNSQ-NITKIGATSKFGSISMLKENDKMSIIHQSPSGIFEHEIELT-
>tr|A0A0H2Q7J2|A0A0H2Q7J2_9ENTE CRISPR-associated protein Cas9 OS=Enterococcus cecorum GN=ABT59_00225 PE=3 SV=1
-VDGQLFDLTLM--K---GQVPIKSSLDISKYGGYNKATGAYFTFVKS--K-KRGK---VVRSFEYVPLHLSKQFENNNEEYIE------VE-ILIPKVL
INSLFRYN-GSLVRIPSRFNDRLDSPLLLENKYIEELKAVSFVRKKDKLGDLNEMYDVIIN-IYQVL---SK---Y-SELVGFRENFVKLDEEEKCKIIY
ELLHLFQCNVV-DLQLIGGVSKFGRLSILKEYDKMSIIHQSPSGIFEHEIELT-
>tr|A0A0I9WT51|A0A0I9WT51_9ENTE CRISPR-associated endonuclease Cas9 OS=Enterococcus cecorum GN=cas9 PE=3 SV=1
-VDGQLFDLTLM--K---GQVPIKSSLDISKYGGYNKATGAYFTFVKS--K-KRGK---VVRSFEYVPLHLSKQFENNNEEYIE------VE-ILIPKVL
INSLFRYN-GSLVRITGR-GDRLEQPLYVSNSFVQQLKSVSYKLKKEKLSNIDELYDGLLR-IYSYW---FS---IKEYLVESRTKYIKLSIEEKALVIF
EILHLFQSDAQ-NLKILGLSTKPSRIRILKDTDKMSIIHQSPSGIFEHEIELT-
>tr|F9MP31|F9MP31_9FIRM CRISPR-associated endonuclease Cas9 OS=Megasphaera sp. UPII 135-E GN=csn1 PE=3 SV=1
-QKGELYDAT-T--KKEGTYFPLKGALDVHRYGGYEKIKIAYYSVFSC--REKASNT--IHTLIIPIPVYKAGLLQ-TEAAYAWKDIYSAIT-PIYKKLC
INTVVKID-GFKYFLGGKTGD-MAIPVVLDEQAAAYLKAISV-GRAITAEANEAFYDVLLK-IFAKA---YQT--IVEKLASARERFRELSIGAQCSCLL
EILNLLANNK-TTKDKMGVTMSRRKQPMLTKLEECIVYETSITGLYEKAVSLL-
>tr|F9N3Y3|F9N3Y3_9FIRM CRISPR-associated protein Cas9/Csn1, subtype II/NMEMI OS=Veillonella sp. oral taxon 780 str. F0422 GN=cas9 PE=4 SV=1
-QKGGLSDET-Y--KKRGVYLPLKSSVDVEKYGGRTSITISEYIILNI--RDTSDQ---DRIEIFSLPLYIAGKKD-IHKEAYLPASVVDIQ-ILYRGLY
IGSKVNIN-GFTYYMGGKTGS-VAVDVVMDITSSVYIKLLEVAIKKVSKEQNIALYQELLK-LFSKM---KGN--KLEEFRTGFDTFIALSLEEQASVLL
EVLNVLTNFK-TDITKIGMTSSRSTLGIISNTEQFSVITTSITGLYEQEIKIK-
>tr|R5BQB0|R5BQB0_9FIRM CRISPR-associated endonuclease Cas9 OS=Veillonella sp. CAG:933 GN=cas9 PE=3 SV=1
-QTGALYDAT-Y--KKSESYVPLKSSLDVKKYGGFTSIKIAYYSIFRF--YKKNSEE--FETHIISIPVLKAGTLN-SKEAYGEKQKFDRVE-LVYKKLC
MNSLVRIN-GVMYYLGGKTNN-LAISLVLPDNIAKKIKAVEYIARVVSPEFNMIIYKALTE-AFVGL---KTN--RENELEKTITAFIAMTLIEQCKMLM
EILNLLTQQK-TA-KPIGVSASRSTLGMITGLSEFTIITQSVTGLQEKEIRII-
>tr|R5SXF4|R5SXF4_9CLOT CRISPR-associated endonuclease Cas9 OS=Clostridium sp. CAG:75 GN=cas9 PE=3 SV=1
-VKGGLFDQNIL--K---GQIPIKGGLSRDKYGAYNKASGAYFMLVES--DGKKGE---RKRTIEFVPVYLAKSLEESVERYCE------PD-VRLSKIR
KNALIDVD-GFKMHLVGRTEN-LATQLVLSEDDQQLIKKIGYCLDHLTMDLFEKLYDIFVF-VYAVK---LS---QAKDLKEVKEEFLALDDEQKCLLLM
EILHLFQCSPQ-NLTNIGGGKSAGSLKIITKQQSVLLINQSITGFYEQVIDLK-
>tr|R9MHT9|R9MHT9_9FIRM CRISPR-associated endonuclease Cas9 OS=Lachnospiraceae bacterium 3-2 GN=cas9 PE=3 SV=1
-VKGGLFDQQLM--K---GQVPIKGRLDIDKYGGYNKAAGTYFMLAES--EDKKGA---KIRSVEYVPLYLCNCIEKDEEKYLQ------PR-VLIAKIK
IDTLFKVD-GFYMWLSGRTGN-LANQLILSEPDMRILKKVLYVNRKLPETDLIRLYDVFLD-VYHVR---LS---QQGTLTKNKDTFCELSNEDKCIVLS
EILHMFQCQSG-NLKLIKGPGSAGILVLISKCNQVSIIHQSPTGIYEQEIDLK-
>tr|D4J3S7|D4J3S7_9FIRM CRISPR-associated endonuclease Cas9 OS=Coprococcus catus GD/7 GN=cas9 PE=3 SV=1
-VKGGLFDQQIM--K---GQVPIKGNLDIEKYGGYNKAAGTYFMLVKS--LDKKGK---EIRTIEFVPLYLKNQIEINHEQYLA------PE-ILLSKIK
IDTLFKVD-GFKMWLSGRTGN-LANQLILSHQEAAILKGVVYVNRKMTEEKLLQLYDTFLD-VYSIR---LS---QIKTLTEKRAKFIGLSNEDQCIVLN
EILHMFQCQSG-NLKLIGGPGSAGILVMITACKQISVINQSPTGIYEKEIDLI-
>tr|A6BJV4|A6BJV4_9FIRM CRISPR-associated endonuclease Cas9 OS=Dorea longicatena DSM 13814 GN=csn1 PE=3 SV=1
-AKGGLFDQQIM--K---GQIAIKETLSIEKYGGYNKAAGAYFMLVES--KDKKGK---TIRTIEFIPLYLKNKIESDESNFLE------PK-ILLKKIK
IDTLFDVD-GFKMWLSGRTGD-LANQLILDEKIIVTMKKIVFIQRRIDNEVLMEIYNTFVD-VYRIR---LS---QAKTLIDKQKEFERLSLEDKSSTLF
EILHIFQCQSS-NLKMIGGPGKAGILVMISKCNKISIINQSPTGIFENEIDLL-
>tr|R6ZAM8|R6ZAM8_9CLOT CRISPR-associated endonuclease Cas9 OS=Clostridium sp. CAG:299 GN=cas9 PE=3 SV=1
-VSGGLFDQQLM--K---GQVYVKSGLSIEKYGGYNKATGAYFMLVES--EGKKGV---KKRTIEFVPLYRKAELEASEEEYLR------PH-VLLHKIK
TDTLFQAD-GFKMHLSGRTGK-LANQFLVAEDYERLLKKVGVTEQLITEEGLKALYSEFLS-PYGNR---LG---QAETLENGKEKFDKLSLENKCQVLS
EILHLFQCNSS-DLSKLGGPGHGGILVLITKCNKISIIHQSPAGIYEQEIDLK-
>tr|B5CL59|B5CL59_9FIRM CRISPR-associated endonuclease Cas9 OS=Ruminococcus lactaris ATCC 29176 GN=csn1 PE=3 SV=1
-VKGGLFDQQIL--K---GQVPVKESLDIGKYGGYNKAAGVYFMLVSS--KDKKGK---EQRTIEFVPIYLKDRVEKDMENYLM------PK-ILIKKIK
IDTLFKVD-GFYMWLSGRTSN-LANQLILSKEDMKTLKKVVYIQRQITEEELLKLYETFLD-IYGAR---LS---QEKTLVNGKEKFIDLSVEAKCQVLY
EILHLFQCQSG-NLKMIGGPASAGILVMISKCKNISIVNQSPTGIYEKEIDLL-
>tr|R5RU71|R5RU71_9CLOT CRISPR-associated endonuclease Cas9 OS=Clostridium sp. CAG:122 GN=cas9 PE=3 SV=1
-VRGGLFDQQIM--K---GQIPVKNNLATEKYGAYNKASGAYFMLVES--EDKKGN---KIRTLEFVPVYLAKELEKSEDRYCV------PD-VRVRKIK
MDSLFNVD-GFRMHLSGRTGK-LAEQLVLDEESQKILKKTAVFADYLTDEMLIKLYELFYK-VYNIR---LS---QVKTLESGKEKFEKLSLLDKCLVIE
EILHLFQCQSV-NLSSIGGAATAGILVLISRCGKVEIINQSITGFYEQVIDLK-
>tr|R7K435|R7K435_9FIRM CRISPR-associated endonuclease Cas9 OS=Subdoligranulum sp. CAG:314 GN=cas9 PE=3 SV=1
-EKGQFYDATIY--P--DKLAPVKGKLDTSKYGGYDKETTAYFMLVKS--RDKKKKD-KTLLSLECVTVLADKNFR-TAEKYCE------PE-ILIEKIK
LNTLFKIN-GSYAWIRGRTND-LANQLWLDNGSAKELKKISHFRDVFSKEQNLALYDLFTE-IYAGL---PVQ--QIKNLEKGRDKFEALELKDQLFVLM
EILKFMQCNSM-NIKLIGGAENAGKNRIIQD-SDVKMIFCSPTGYFCKVVDFK-
>tr|E0NJ84|E0NJ84_9FIRM CRISPR-associated endonuclease Cas9 OS=Peptoniphilus duerdenii ATCC BAA-1640 GN=csn1 PE=3 SV=1
-GTGGLYDQNLM--R---GQIPQKENKNIEKYGGYNKASSAYFALIES--D-GKAG---RERTLETIPIMVYNQEKGNTEKYLK------PK-ILKDKIK
INSLIKLD-GFLYNIKGKTGD-LSVQLIVNKEEQKLIKKMDFLVKKIKEEELIKLYKTLSD-IYSNK---RN---QAKNISEALDKFKEISIEEKIDVLN
QIILLFQSYNN-NLKSIGLSAKTGVVFILNY-KECKLINQSITGLFENEVDLL-
>tr|C2CKI6|C2CKI6_9FIRM CRISPR-associated endonuclease Cas9 OS=Anaerococcus tetradius ATCC 35098 GN=csn1 PE=3 SV=1
-KCEDLFDENIV--R---GKFPIKENKDTNKYGGYSGIKNAYFVLLED--E-K-H-----NRILEAIPSFIYKKEKGEKGNYLQ------AK-ILRDKIK
IGSLLKID-KFPYNLAGKSGN-IGVQLILDKNTSKYIKKIEYKYKLLSKEENIKLFDLFVD-IYKNR---VN---KLKEIKLARPKFEHLSIEEQIKTLT
QMLILFGRENN-NLEYIGLPKNTGKTKIINN-KDIKIINQSITGLYETEEDLA-
>tr|J3JPT0|J3JPT0_STRRT CRISPR-associated endonuclease Cas9 OS=Streptococcus ratti FA-1 = DSM 20564 GN=cas9 PE=3 SV=1
-QTGGL--ETIYP--SFD----RKNTL-ASKYGGFGSPTVAYCVLVVADSKNENGKVKKLGSELLGITILEKNDFENNSLDFLSRKGYQGVQEKKIIKLP
KYSLFEFQDGSRRMLSSANDNRGANEMILPAYLVKLLYHAKINSVGYINSEFQDLLNYIRQ---DKF---VDVD-NLSKIRS---L-SKSSVSEICSS--
NLLTLTALGAPA-FKFFGTTIPR--YGS---ILSATLIHQSITGLYETRIDLS-
>tr|E6LI02|E6LI02_9ENTE CRISPR-associated endonuclease Cas9 OS=Enterococcus italicus DSM 15952 GN=cas9 PE=3 SV=1
-QKGGFSKESIQP--ESQKLIRRKQQW-TKKYGGFDSPVVAYAILLSFD--KGKRKA--RSFKIVGITIQDRESFEGNPILYLSKKDYHNPK--VEAILP
KYSLFEFENGRRRMVAS----ASGNQLIIPGHLMELLYHSKIINGKYIQEKFREIFEYIVD---SKY---ISAD-NLNKIEK---IFENNSEQEIAKS--
NLLTFTAMGAPA-FEFFGEKI--KRYV-ISEIIDAVFIHQSITGLYETRVRLT-
>tr|A0A0A8K7X7|A0A0A8K7X7_STRMG CRISPR-associated endonuclease Cas9 OS=Streptococcus mutans GN=cas9 PE=3 SV=1
-QTIGQ--GLFDD--KSPLEVILKKAL-PEKYGGYQKPTTAYPILLIVDT-----------KQLIPISVMDKKRFEQNPVKFLKDKGYQQIEKNNFVKLP
KYTLVDIGNGIKRLWAS-----KGNQLVVSKKSQDLLYHAHL---DYVKQQFDILFNEITS---KKC---KLGK-HIQKIEE---AYSKESIEELADG--
KLLGFTQLGATS-FSFLGIKLNQ--YTGLLPCMEATLIHQSITGLYETRIDLS-
>tr|A0A0E4H4H8|A0A0E4H4H8_9STRE CRISPR-associated endonuclease Cas9 OS=Streptococcus sp. FF10 GN=cas9 PE=3 SV=1
-QTGGF--ESILP--GSD-KLIKNNYL-TQKYGGFDSPTVAYSIMFVADI--EKGKSKKTVKEMIGITIMERSRFESNSVTFLEEKGYRNIRENTIIKFP
KYSLFELENGRRRLLAS-----IGNEMFLPQQFVNLLYHAQANKE-YLEHELSELFHHIIG---EKT---ILKP-VEMTLNE---AFEKHEVSELAQS--
SLLKFTAFGAPG-FKFLDADIKQ--LRYVTEVLSSTLIHQSVTGLYETRIDLS-
>tr|R6ET93|R6ET93_9FIRM CRISPR-associated endonuclease Cas9 OS=Firmicutes bacterium CAG:145 GN=cas9 PE=3 SV=1
-GKGELFNATIA--K---AEIPLKAG-QTGKYGGYKSPNTSYFAAIEF--DGKKGE---RVKNIMEVPVYIANILLHDIDRYCE------VK-ILRPCIK
KNALISVD-GYPMRIRGANEK-INLQPIFGRH-EETV----RIEKYLNEANLTDLYDDITE-PYVER---PS---QGEYLMENREKFLNISLKEKAKLLA
QMIKLVRCDTETDLRSIGASKNAGVISVTLGGKRLILINQSVTGLFENRIEL--
>tr|R7PQD7|R7PQD7_9FIRM CRISPR-associated endonuclease Csn1 family OS=Dialister sp. CAG:588 GN=BN722_01041 PE=4 SV=1
-GQGELFDQLPL--K---GQVSLKKEIDISKYGGYNSASTAYFMYVEG--EDNKGK---PVYVIETMPLHLAARLTTLEEKYCE------PK-VLIEQIP
IQSLFSVD-GFRVTIAGKTGK-YAEELVLNNGYAMTLKAVLFVNRRLEESQLLALYDVFLD-CFSKR---FS---QRDVLKNGRESYIALSLEDKCQILS
EILHLFQCNAT-NLNLLGSSKQSGRLYMLSDKDSWYIIHQSVTGFYEQHIPLA-
>tr|R6P3Z6|R6P3Z6_9FIRM CRISPR-associated endonuclease Cas9 OS=Eubacterium sp. CAG:274 GN=cas9 PE=3 SV=1
-NKGELFDQNPLKAS---TLVPLKKG-EVWKYGGYNSITPSYFMLVES--KDKKGN---YIRTIETMPLYREKEFSKNEENYCK------PK-IILKCIK
KNALLIVD-GFPMHLKGSTGL-LAVQLILESDMVIYLKKLMFVNENLSAKENIKLYDIFIQ-IYSKR---PA---PVEKLINARDIFIELTVKEQCIVLS
EILHLFQCKPLTNLVSINLKKTVGIIQIITA-KNVKLVHQSPTGIYEYTVDLN-
>tr|D6GRK4|D6GRK4_FILAD CRISPR-associated endonuclease Cas9 OS=Filifactor alocis (strain ATCC 35896 / D40 B5) GN=cas9 PE=3 SV=1
-EKGELFNATIQ--K---STVSLKKG-DVKKYGGYFSANTSYFSLIEF--EDKKGD---RARHIIGVPIYIANMLEHSPSEYCE------VR-ILVEKIK
KNSLLIIN-GYPLRIRGENEV-TAIQLKLDQKNYELVRNIEFLEKYITHEKMNQLYEVLLS-FNKKG---MA---PSDRIEKSKPKFIKLDLIDKINVIN
KMLNLLRCDNDTDLSLIELPKNAGSFVVTIGKSKIILVNQSVTGLYENRREL--
>tr|J7M7J1|J7M7J1_STRP1 CRISPR-associated endonuclease Cas9 OS=Streptococcus pyogenes M1 476 GN=cas9 PE=3 SV=1
-QTGGFSKESILP--NSDKLIARKKDW-PKKYGGFDSPTVAYSVLVVAK--VEKGKSKKSVKELLGITIMERSSFEKNPIDFLEAKGYKEVKKDLIIKLP
KYSLFELENGRKRMLAS----AGGNELALPSKYVNFLYLASYEKLKFVEHYLDEIIEQISE---KRV---ILAD-NLDKVLS---AYNKHI-REQAEN--
HLFTLTNLGAPA-FKYFDT--TIKRYT-TKEVLDATLIHQSITGLYETRIDLS-
>tr|A0A0P6SHS4|A0A0P6SHS4_9STRE CRISPR-associated protein Csn1 OS=Streptococcus phocae GN=AKK44_08325 PE=4 SV=1
-QTGGFSNETILS--KSSKLIPRKNKWDTTKYGGFNTPTVAYSVLVVAK--VEKGKAKKPVKELVGITIMERTKFEANPIAFLESKGYHDIQEHLMITLP
KYSLFELENGRRRLLAS----ATGNEMVLPQHLVTFLYRVSRDKGTYISEKFIEIFHYIIR---EKN---VIKP-VIERLND---TFNQKDLTELSIS--
NLFKFTSFGAPE-FTFLNSEIKQVRYR-TKECLNSTLIHQSVTGLYETRIDLS-
>tr|K4Q9P5|K4Q9P5_STREQ CRISPR-associated endonuclease Cas9 OS=Streptococcus dysgalactiae subsp. equisimilis AC-2713 GN=cas9 PE=3 SV=1
-QTGALTNESIYA--SFDKLISRKHRF-SSKYGGFGSPTVTYSVLVVAKSKVQDGKVKKTGKELIGITLLDKLVFEKNPLKFIEDKGYGNVQIDKCIKLP
KYSLFEFENGTRRMLASANNNRGANEMFLPAKLVTLLYHAHIESSKYILNDLYQLLSYIER---SLY---VDVE-NISKVKE---LFSNII-SEICSS--
NLLTLTASGAPA-FKFLGT--TIKRYG-PQSILSSTLIHQSITGLYETRIDLS-
>tr|R5GJ26|R5GJ26_9FIRM CRISPR-associated endonuclease Cas9 OS=Eubacterium sp. CAG:786 GN=cas9 PE=3 SV=1
-RKGALFNLMPE--R---SLLPRKNGVPAEKYGGYNNTAASFFSLVKY--HSAKGS----GVVIIPVELIHAHRYEHDSSEYALVLQSVEFP-LGSRILK
VNTLLDID-GFRANITGKDSGYLASSLIISQVDTTYIKRVIINERIITSERNIEIYNMLCE-PFCIK---FAN--TSDTFVSGREKFIALSLNEQVKTLT
NMLSVFKTGRASDLTNIGGSKNTAIVKLLSNFKSVRIIDQSPTGLYEKVSPNL-
>tr|R5N3I1|R5N3I1_9FIRM CRISPR-associated endonuclease Cas9 OS=Eubacterium sp. CAG:180 GN=cas9 PE=3 SV=1
-KQGGLFKINPL--K---GQVPLKASRCIEKYGGYDKATSAYFSYVEY--TDKKGK---AVRQMFPVNLYEVKEYEADMQGFVT-----NVK-ILIPCVK
YDACISFD-GC--RMFITKKTRIGMQLVLGYKYEKYIRNIEYLTKHISAEENIELYDILTG-VLSVK---FSG--IGKKLEKRREKFVLCSPEEQCCVLN
EILKILHANVL-DLSLIGESPNTGTMKTFSEVHSIKLINQSVTGLFEQEIDLL-
>tr|C0WE68|C0WE68_9FIRM CRISPR-associated endonuclease Cas9 OS=Acidaminococcus sp. D21 GN=csn1 PE=3 SV=1
-RKEGLFDIQPL--K---GLVPRKAG-DVVKYGGYDKSTAAYYLLVRF--TLEDKKT-QHKLMMIPVEGLYKARIDHDKEDYAQKVINIMFP-MGTRHIK
LNSMISID-GFYLSIGGKSSKSVMVPLIVPHKIECYIKAMEFA---ITVEDNLNLYELFLQ-PYNKF---FST--QFDVLTNGRSTFTKLSPEEQVQTLL
NILSIFKTCRSSDLKSINGSAQAARIMILTGYSDIRLVEQSASGLFVSKSQNL-
>tr|R6TGN6|R6TGN6_9FIRM CRISPR-associated endonuclease Cas9 OS=Eubacterium rectale CAG:36 GN=cas9 PE=3 SV=1
-KTGGFFDQMPC--K---GLVPRKKG-DTERYGGYNKSGIMFLTPMRY--KIGKKS----DIIILSIELLYGKLFLKDEVKYAE-ADEVSFP-MGMKPWK
INTVLSLD-GFNVCITGIGGGCLIMQLSLPYELAKYLKKIEFV---VSVDENIKLYDVYLD-IYNKR---INS--PEAILKNGREKFCKLNVLEQAVTLI
NIQSIFGRM-TGDLENIGGKKHSATVNFVSNYNDVRVVYQSPSGIWERRSQNL-
>tr|G5KAN2|G5KAN2_9STRE CRISPR-associated endonuclease Cas9 OS=Streptococcus pseudoporcinus LQ 940-04 GN=cas9 PE=3 SV=1
-QSGAFSKESVLS--NSDKLIERKKGW-PKKYGGFDSPNTAYSIFVVAK--VAKRKAQKTVKEIVGITIMEQAEYEKDNIAFLEKKGYQDIQEKLLIKLP
KYSLFELENGRRRLLAS----ANGNELALSGKYMKFLYLASYDKLSFVEHYFDEILDIVVK---TCY---IKAE-NLKKIIS---LYKKKI-NEQALN--
NLFIFTSLGAPS-FVFFDE--TIKRYT-SSDVLNGILIQQSITGLYETRIDLS-
>tr|I7QXF2|I7QXF2_STRCB CRISPR-associated endonuclease Cas9 OS=Streptococcus canis FSL Z3-227 GN=cas9 PE=3 SV=1
-QTGGFSKESILS--ESAKLIPRKKGW-TRKYGGFGSPTVAYSILVVAK--VEKGKAKKSVKVLVGITIMEKGSYEKDPIGFLEAKGYKDIKKELIFKLP
KYSLFELENGRRRMLAS----ATANELVLPQHLVRLLYYTQISATTYIEEEFKEIFEKIID---EKY---ILKN-VNSNLKS---SFDEQDSILLSNS--
SLLKYTSFGASG-FTFLDLDVKQLRYQ-VTEVLDATLIYQSITGLYETRTDLS-
>tr|E9FJ16|E9FJ16_9STRE CRISPR-associated endonuclease Cas9 OS=Streptococcus sp. C300 GN=cas9 PE=3 SV=1
-QTVGQFDNNIVS--KVVDASK-KSGL-PEKYGGYARPTIAYSVLVTYKQN---NK---IKNTMVGIPVLTKLEFERDPNLYLRNLGINNVSH--VIKLV
KYTVLEFKHKYRRFIVS------ANQIFVTTKQMKLISQYT---LDLLKQLIQSIWNQFLE---TDL---VNKK-YDELIL-------TNTIEE-CRNM-
TTLSFTNINAGQ-KIIFDDTLSLKRWQFVKKIIESTLIHQSITGLYETRIDLS-
>tr|K8MQ90|K8MQ90_9STRE CRISPR-associated endonuclease Cas9 OS=Streptococcus sp. F0441 GN=cas9 PE=3 SV=1
-QTGGF---SILP--N---SDKKDILW-TTKYGGFDSPVIAYSILLIADIEKG-KAKKKTVKTLVGITIMEKDAFEKNPIAFLENKGYHNVCKENILCLP
KYSLFELENG--RLLAS------CNEIVLPVYLTTLLYHSKVHKLDYIQNEFKDLLNLVSE---QKY---VLAD-NLEKIK----NLYADDIEILANS--
NLLTFTALGAPA-FKFFG----KD--RKVSEILNATLIHQSITGLYETRIDLS-
>tr|E8JP81|E8JP81_STREI CRISPR-associated endonuclease Cas9 OS=Streptococcus equinus ATCC 9812 GN=cas9 PE=3 SV=1
-QT---SKESILP--DSDKLIPKKLQW-TQKYGGFDSPTVAYSVLVVADVEKGKTRKLKTVKELVGISIMERSSFEENPVSFLEKKGYHNVQEDKLIKLP
KYSLFEFEGGRRRLLAS-----TGNEVVLPQYMVNLLYHSQVNNSHYVKDEFKDIFNLIIS---RIN---ILKP-VVDNLI----NEFTEDISSLS----
NLLKFISFGAPG-FKFLKLDVKQLRYK-TTEALSATLIHQSVTGLYETRIDLS-
>tr|I4X9B8|I4X9B8_9BACL CRISPR-associated endonuclease Cas9 OS=Planococcus antarcticus DSM 14505 GN=cas9 PE=3 SV=1
-GDGMFYKESIFSPKV-----------PKTEKFVHDEVKNHSICLVEF--TFMKKEKEVQETKFIDLKVIEHHFLKEPESKFLANSPIIHAR-IIR-TIP
KYQKIWIE-HFPYYFISTRELHNARQFEISYELMEKVKQLS-------VEELKIVFGLLIDQMNDNY---PIYTKSSI--QDRVQKFVDT----SFEIFE
ELKKAVAANAQRD--------TFGSRISKPKPEEVAIGYESITGLKYRKPRSV-
>tr|F5WVJ4|F5WVJ4_STRG1 CRISPR-associated endonuclease Cas9 OS=Streptococcus gallolyticus (strain ATCC 43143 / F-1867) GN=csn1B PE=3 SV=1
-QT---SKESILP--NSDKLIPKKFRW-TPKYGGFDSPNIAYSVFVIADVEKGKAKKLKTVKELVGISIMERSSFEENPVVFLEKKGYQNVQEDNLIKLP
KYSLFEFEGGRRRLLAS-----SGNEVVLSRHLVELLYHAHVNSFNYVSKEFGEVLSCVEN---KSY---VDVE-NLGKIR----AVADKSIEDIS----
NLLTLTALGAPA-FNFLGEKI--KRYT-TKECLNATLIHQSITGLYETRIDLS-
>tr|A0A060RIR3|A0A060RIR3_9STRE CRISPR-associated endonuclease Cas9 OS=Streptococcus gallolyticus GN=cas9 PE=3 SV=1
-QT---SKESILP--DSDKLIPKKVYW-TKKYGGFDSPTVAYSVFVVADVEKGKAKKLKTVKELVGISIMERSFFEENPVEFLENKGYHNIREDKLIKLP
KYSLFEFEGGRRRLLAS-----SGNEMVLPGYLVELLYHAHADNFNYVSKEFEKVLSCVED---NLY---VDVE-NLSKIR----AVADSSIEEIS----
NLLTLTALGAPA-FNFLGEKI--KRYT-TKECLNATLIHQSITGLYETRIDLS-
>tr|S5R5C8|S5R5C8_9STRE CRISPR-associated endonuclease Cas9 OS=Streptococcus lutetiensis 033 GN=cas9 PE=3 SV=1
-QTVGQFDNNILA--EKDDKKKIKKSL-TTSYGGYARATIAYSILIVSEFGKNKE-----L-KLLGLPLLDKVKYEKNPIAYLNSIGIINVK--SIFKLP
KYCLFEFQEKYRRYMVS-----QANQLFLTCKETELVYKYISDNDN-VG-TILSIWNKLVI---RTK---LIDK-LFASLK----QLKDENILDMT----
--LDFTKISAGQ-KITISDSLSLKRWQFLKQLKTATLIHQSVTGLYETRIDLS-
>tr|A0A0H1U9K5|A0A0H1U9K5_STRAG CRISPR-associated endonuclease Cas9 OS=Streptococcus agalactiae GN=cas9 PE=3 SV=1
-QTGGFSKESILA--NSDKLIPKDIYL-PKKYGGFDSPIVAYSVLVVADIKKGKAQKLKTVTELLGITIMERSRFEKNPSAFLESKGYLNIRDDKLMILP
KYSLFELENGRRRLLAS----AGGNELALPTQFMKFLYLASYNELKFVVSYFDDILQIIND---NRV---ILAD-NLEKINK---LYQDNPVDELANN--
NLFTFTSLGAPA-FKFFDKIV--KRYT-TKEVLNSTLIHKSITGLYETRIDLG-
>tr|R6TGA0|R6TGA0_9STAP CRISPR-associated endonuclease Cas9 OS=Staphylococcus sp. CAG:324 GN=cas9 PE=3 SV=1
-KSNKMFSKSSIS--NSKNLIPIKTSRNVLKYGGIKSNSYNFYCIVEL--YDKKGKK--SY-ILEAIPKTHS-------DEYIKEKNVSNFK-IINKNIK
SNIIIEYKKSGKYYLIKNFKD---RNFSY----NAI-KTIKYIEKYNCQALLDEIISLFKKDI-YNY---DIIYKITSKLEENKQN----TLTNLIKVLT
EILILLKTNERGADL-IDMSKDTGTLCIKTLKPGMKFISESPTGYYRKIIF-E-
>tr|G7SP82|G7SP82_STRSU CRISPR-associated endonuclease Cas9 OS=Streptococcus suis ST1 GN=cas9 PE=3 SV=1
-QNHGLYNANLSP--KEGSVENAKQSF-TKRYGGYAGISNSYAVLVNGIIEKGKKKSKAEVTEFQGISILARKDFDKNPKQYLLNLGYKDIK--SIIKLP
KYSLFELENGSRRMLASSTNNRGGNEMYLPDKFVTLLYHAMVNRTLYVEHVFDELLIYILE---K-I---VGAK-NGKRIVE---AYSARNLEELCN---
NLLNLTALGSAV-FEFLGTKIPRD-Y--PSSLLKATLIHQSVTGLYETRIDLS-
>tr|G9WGU4|G9WGU4_9LACT CRISPR-associated endonuclease Cas9 OS=Oenococcus kitaharae DSM 17330 GN=cas9 PE=3 SV=1
-QKGQLYDESRYPSVK-SKASINFDKHPVDLYGGFSSAKPAYAALIKF--KNKFR--------LVNVLRQWTYSDKNSEDEQIRK--YPKAE-MVLSHIP
YGQLVKK-DGALVTISSATELHNFEQLWLPLADYKLINTL-LKTKETIESAFYKAFDSILS--FNRY---ALHQNALVKLQAHRDDFNALNYEDKQQTLE
RILDALHASPA-DLK--NLSSGFGRLFSFTLADTDEFIFQSVTGLFSTQKTVA-
>tr|J9YH95|J9YH95_LEUGJ CRISPR-associated endonuclease Cas9 OS=Leuconostoc gelidum (strain JB7) GN=cas9 PE=3 SV=1
-SSGRLYAETLFSPN--KAKLIAQKANSVALYGGFTKAESAYTALVEF--NKKGDR----SYKLIKVPMAIANRVNDKQIAYIALNLRDFSR-VVLEHLP
LGTLIRESDGSEFYAASSEYKHNAKELWAPKEILRSSKKL-DKATA---------------KTISNF---KFYEKDLLHLKNVRDKFVEASDEIKIKVLS
DVIYELHNDAGWPFK--QEKPAWTMLQVIKLSEKAAIVYQSPTGLFETITIVG-
>tr|X0QNI0|X0QNI0_9LACO CRISPR-associated endonuclease Cas9 OS=Lactobacillus composti DSM 18527 = JCM 14202 GN=cas9 PE=3 SV=1
-QTGTLYNETRYGSG--KHVAVALSKDAADLYGGFGSLKPAYAALVYS--KKKFR--------LVNVLRLWLPEIKKNASRKVQVLGDDNAK-VIRAHVP
CGQLLIK-DGALVTVSSATELHNFRQLWLPKADYQDISIL-LGAPDDVDQRFESLLKDVIDRQYYPL---KTHQTSLEKLIGKIGKFDELKFAQKQQVFS
RLLSALHANAT-DLK--GLSTAWGRLIYVSLTDEDKLINSSFTGLFNDVMSIK-
>tr|A0A0R2JE56|A0A0R2JE56_9LACT CRISPR associated protein OS=Weissella kandleri GN=IV73_GL000096 PE=4 SV=1
--AGKLYQRVTVKPK--SGEAPVNHQKDINIYGGVTSEQAAELVLIRI--KAKNNA----KNMVIKIPTAIANQVANKTTAYVRLNIPNYAG-IILDQIP
LGQLVFD-ERTSFYLASAEIKHNARQLWVNQHINNVLTKKNNDEER-----------NLLTKNLERF---KLLEPDLKRVKAAKQQWASCDDQEQMQILR
IIINKMHDDASPPFKLDKQGKGWRDLRTMKLSDNAEFVYQSPTGLYHRKISIN-
>tr|R5JYM0|R5JYM0_9FIRM CRISPR-associated protein Cas9/Csn1 subtype II/NMEMI OS=Coprococcus sp. CAG:782 GN=BN781_00492 PE=4 SV=1
-RHGKLY-NVSIG-SSKDMYIPSKLNLDVKKYGGYSDVKGTYFFLVEY--T-EKGK---RVRSLEALPLYLKDHYNT-KEEYCR------PS-VRYRRIK
MYSKIRVN-GFEVLLTGRSE-RLAEELKISYQDAKYIKNLALKERDATREENGKVFLMLKD-IYAKR---INP--IGDKL--DENKFNNLSLKQQAEIIL
QLVGITQQTN-YNLELIGASKKTGTMKPLSSYSEVLLINQSVLGIYEERVDLL-
>tr|R5Z6B4|R5Z6B4_9FIRM CRISPR-associated endonuclease Cas9 OS=Eubacterium sp. CAG:156 GN=cas9 PE=3 SV=1
-KHSGQKGGISQN-SKKNVYLPIKMGLNVEKYGGYGSLTAKYFFLVEH--T-IKKK---RIRTIEAYPMYLDA-LNK-ENNYCV------PK-IIMEKIK
VKSLFKIN-GYYYYLNAKSV-RIATQLFLENDINEYVRKISN----INSENNIKVYDIFIE-LFSNR---LGN--LKEAIIQNRNKFIELKINEQINVIL
ELVRYSQDGV-YNLSQLGLSSTYAINRTISKMKECKLINQSVTGLYENEIDLL-
>tr|R5YGP2|R5YGP2_9FIRM CRISPR-associated endonuclease Cas9 OS=Roseburia sp. CAG:197 GN=cas9 PE=3 SV=1
-GKGGL----TET-SKEEGYIPFKSSMDVTKYGGFTSVTGAYFFLVEH--T-EKKK---RSRMIESVPLYLAQKIEQNPHKYCE------FD-IRVRKIK
IGSLIKRK-GYFFYITGKTG-RLAVNMCLKKEWVKYISKLEAVDKNITKEKNELLYSELIE-IFSNR---PNP--VGDKLDEAKEKFINLDIEKQCIVLC
QILQLSSVLG-SDMTLLGESAHCGKILIIG-DEDIYLINQSVTGLYEKKINLR-
>tr|R9LW52|R9LW52_9FIRM CRISPR-associated endonuclease Cas9 OS=Firmicutes bacterium M10-2 GN=cas9 PE=3 SV=1
-ANGTIAKAT----PKDQGYLPRKTSLDMKKYGGVTSIQIAYFFLVEH--E-VKKK---RIRTIECVPIYRKEELKT-KERYCR------PS-IRLEKIK
PYSLLKMN-GNFFYITGKTN-RFAMELYVDKVSENHIRDLVYKNCGEARKRNERLYTILTK-VFKGS---PKP--MGEKLQQYQQLFLELEVSKQVYVLL
QILQLTATNVKTDLTAIGGKANEGTMDILENVPELMLINQSPTGLFESEIDLL-
>tr|U2PI18|U2PI18_EUBRA CRISPR-associated endonuclease Cas9 OS=Eubacterium ramulus ATCC 29099 GN=cas9 PE=3 SV=1
-KHGGITQKATWS-KNTDAYIPVKMNLDVTKYGGVTTIAVAGYTLLEY--K-AGGK---TVRSLEALPIYLGGSKKLTEEEYFSEKVVSDVI-IRKKMIP
SGSLIKYN-GFYYYLAGKTG-RIAVQLCLPMDTMLYIKKIEACSTGLSKQQNEFVYELIIQ-IFKKK---VGA--IGDTIIEKREKFAEISLEEQCKVLM
QIFLN-FQSG-IELKIIEGGKKSGVTYLVMNVQELKLIDQSVTGVFSREIDLL-
>tr|J4KB57|J4KB57_9FIRM CRISPR-associated endonuclease Cas9 OS=Peptostreptococcaceae bacterium AS15 GN=cas9 PE=3 SV=1
-GHGSITKET-VGVTNLQAYRPIKTSLNILRYGGRTSISISGYCLVEY--V-KKRK---TIRSLEAIPVYLGRKDSLSEENYFR-DSVSDIR-LCLPFIS
TNSLVKID-GYLYYLGGKND-RIAYQLKMKKEEVEYIRKIEAVSMSLTEEKNIELYNKIQD-VFSKR---MSLVKFGDFLKNKKSKFEEIDLEKQCKVLY
NIIFN-LSNL-KDLSDIGGSKSTGKCRCITNYKEFKLIQQSITGLYSCEKDLM-
>tr|R7D1C6|R7D1C6_9ACTN CRISPR-associated endonuclease Cas9 OS=Collinsella sp. CAG:289 GN=cas9 PE=3 SV=1
-DTGAFWNATVYSPRGPKLALSTKQG-DPKLYGGFSSQQFAYFFIYEA--KK--KGK--PTFRFSQVPVWLAARIEANPLEYARGEGLEFVS-IQRPKIY
KKQLIEVN-GDKLIITGAKEVRSGAELAFNQDEISAISMCSLRAAEAFSEEVSAIWNRISNAPVQSC---GRLLR-QLTLPKYQSNFDSSSNEEKAAVVL
GLIALLNGNNRID--GVGGSSHAGAMMMDDPKVPFFIIDQSVTGMFERKTRVG-
>tr|A0A0F2DWP8|A0A0F2DWP8_STRMT CRISPR-associated endonuclease Cas9 OS=Streptococcus mitis GN=cas9 PE=3 SV=1
-QTVGQFDNNIVS--KVVDASK-KSGL-PEKYGGYARPTIAYSVLVIADIEKG-KAKKKRIKEMVGITVQDKKKFEANPIAYLEECGYKNINPNLIIKLP
KYSLFEFNNG--RLLAS------GNELIVPYHFTALLYHAQINKISYVESEFKELLTAIIS---KKY---IQKP-VESLLQ----QAFDQDIYQLSES--
SLLKLISFGAPG-FKFLG----VS--QSVSSCFNATLIHQSITGLYETRIDLS-
>tr|F0I6Z8|F0I6Z8_STRSA CRISPR-associated endonuclease Cas9 OS=Streptococcus sanguinis SK115 GN=cas9 PE=3 SV=1
-QTVGQFDNNIVS--KVVDASK-KSSL-PEKYGGYARPTIAYSVLVIADIEKGKGKAKKRIKEIVGITIQDKKKFESNPVTYLEECGYKNINSNLIIKLP
KYSLFEFNDG--RLLAS------GNELILPYHLTALLYHAQINKISYVENEFKELLTTIIS---KKY---IQKP-VELLLQ----QAFDQDIYQLSES--
SLLKLTSFGAPG-FKFLG----VS--QSNSQFLDTTLIHQSITGLYETRIDLS-
>tr|E1LI65|E1LI65_STRMT CRISPR-associated endonuclease Cas9 OS=Streptococcus mitis SK321 GN=cas9 PE=3 SV=1
-QTHGLFNSNPSP--SEDRKEN-KQGL-PRKYGGYAGISNSYAVLVKAIIEKGAKKQQKTVLEFQGISILDKINFEKNKENYLLEKGYIKILS--TITLP
KYSLFEFPDG--RRLASSTNNRGGNELVIPEKYTTLLYHAKINKTLYVENDFAKLLEYVLN---DKY---VGAL-NGERIR----QAFIDDIEKLCFSI-
GLFELTSQGSAS-FEFLG----VP--RYPSSLLNATLIHQSITGLYETRIDLS-
>tr|A0A0R2KGU9|A0A0R2KGU9_9LACO CRISPR-associated protein, Csn1 family OS=Lactobacillus ceti DSM 22408 GN=IV53_GL000556 PE=4 SV=1
-ITSPISNET-H--KKPGSYLPRKSSLDVTKYGGYEKIKNAYYSIYKYTYMKKKECM--EEFLLVPIPIHLVNNDE-ELPKYINKKKLETVE-CIVKELY
QGTLVRIN-GYDYRIAGSSGK-FGINLIVEPWVEKVLKETDFVRKSLIEKQLNDVFEYLCR-IFKNN---KHT--LPAKLLGIQKRFEDASIEDEFEVIK
ELISAIAKNP-QKLDISGSSIPRFNLKLKNNVDEFIIKNESVTGLFTHEKVIF-
>tr|D7N6R3|D7N6R3_9FIRM CRISPR-associated endonuclease Cas9 OS=Peptoniphilus sp. oral taxon 386 str. F0131 GN=csn1 PE=3 SV=1
-TRGELYDAT-Y--KKTGSYMPLKSSLDVTKYGGYTKIKIAYYSVYKYKFSDKNLIK--TEIRLIPIPIYLSKNDD-DIKEYVKSKL-IDFT-KIYDKLY
VNSLIKIN-GYLYYLGGKTND-VAVSIVLDDKIEYLIKRISDIKY-VSDDELMDIYESLAE-IFYNR---LSD--FEKIFSNVKKKFVKLEKNDKCRVLL
QLLNVLTDSQ-T-LEMVGLKHSRSNIGMISNLEEFKVINSSITGLYSNEIDIL-
>tr|M2SLU3|M2SLU3_TREDN CRISPR-associated endonuclease Cas9 OS=Treponema denticola US-Trep GN=cas9 PE=3 SV=1
-KKGGLFDQTIMKK--GLGQHPLKKEFNISKYGGYNKVSAAYYTLIEY--EEK-GN---KIRSLETIPLYLVKDIQDQDVSYLT--GKKEFK-ILVPKIK
INSLLKIN-GFPCHITGKTNDSFAVQFCCSNDEVLYFKKIIFSEIRLLQKKNLEIYDMLLT-IYKKR---PNSA-TIDILVKGKEKFKSLIIENQFEVIL
EILKLFSATRNVDLQHIGGSKYSGVAKIISSLDNCILIYQSITGIFEKRIDLL-
>tr|M2CIC2|M2CIC2_TREDN CRISPR-associated endonuclease Cas9 OS=Treponema denticola H1-T GN=cas9 PE=3 SV=1
-KKGELFNQTIMKK--GLGQHPLKKEFNISKYGGYNKVSAAYYTLIEY--EEK-VN---KIRSLETIPLYLVKDIQDQDVSYLT--GKKEIK-ILVPKIK
INSLLKIN-GFPCHITGKTGDSFAVQFCCSNDEVLYFKKIIFNEIRLLQKKNLEIYDMLLT-IYNKR---PNST-TLGMLTKGRYEFINLKPKDQIIVML
EILKLFCTTREADLGLIKGKPAAGVATLISNLDNCILIYQSITGIFEKRIDLL-
>tr|R5R3T7|R5R3T7_9FIRM CRISPR-associated endonuclease Cas9 OS=Firmicutes bacterium CAG:194 GN=cas9 PE=3 SV=1
-QRGELYDLQ----SKKENYVPIKATMDVTKYGGFTSLNPAYFVFVEY--G-SAKK---RQRCFAVVHSYWASSIKNNEDHL--DRGYENPI-VIADKIK
KNSLIKYN-GYFLYIVGMDARQVATSMCLNNNFIQYIQKIEANTLIITAERNIALYNELKK-IFKNH---PKG--IGSVLESGEGAFVQLSLEQQIGILY
SIIQFSSFKK-GSLTLIGGPKEVGRIRIMPKARELKLIHYSITGMYKKEINLL-
>tr|F5U0T2|F5U0T2_STRAP CRISPR-associated endonuclease Cas9 OS=Streptococcus anginosus SK52 = DSM 20563 GN=cas9 PE=3 SV=1
-QTHGLFNANPSP--KPDSSENIKRNL-PKKYGGYAGISNSYAVLVKAIIEKGVKKKETMVLEFQGISILDRITFEKDKRAFLLGKGYKDI--KKIIELP
KYSLFELKDGSRRMLASSTNNRGGNELFVPQKFTTLLYHAKINNPIYVKDDFKELLNYVLE---EKY---VGAT-NGERLK----EAVADSNEEICTSL-
GLFELTSLGSAS-FEFLGVKIPR-DYT-SSLLKDSILIHQSITGLYETRIDLS-
>tr|G5JVJ9|G5JVJ9_9STRE CRISPR-associated endonuclease Cas9 OS=Streptococcus macacae NCTC 11558 GN=cas9 PE=3 SV=1
-QTVGQ--GLFDD--KSPLEVTLKKEL-PKKYGGYQKPTTAYPVLLITDT-----------KQLIPISVMNKKQFEQNPVKFLRDRGYQQVGKNDFIKLP
KYTLVDIGDGIKRLWAS-----KGNQLVVSKKSQILLYHAHL---DYLQQQFDVLFNEIIS---KKC---KLGK-HIQKIEN---VYSNKSIEELAES--
KLLGFTQLGATS-FNFLGVKLNQ--YKGILPCTEGTLIRQSITGLYETRVDLS-
>tr|U2YFI6|U2YFI6_STRAP CRISPR-associated endonuclease Cas9 OS=Streptococcus anginosus T5 GN=cas9 PE=3 SV=1
-QTGGF-----LP--ESDKLIPKNSYW-PKKYGGFDSPVVAYSILVFADVEKGKSKKLRKVQDMVGITIMEKKRFEKNPVDFLEQRGYRNVRLEKIIKLP
KYSLFELENKRRRLLAS-----RGNELVIPQRFTTLLYHSYIEKNYYVEDEFKELLEYISV---RKY---VLAD-NLTKIE----MLFSKEVSSLA----
SLLTFTAFGAPA-FNFFGENIDR--YT-VTECLNATLIHQSITGLYETRIDLS-
>tr|U2QKG2|U2QKG2_9BACL CRISPR-associated endonuclease Cas9 OS=Gemella bergeriae ATCC 700627 GN=cas9 PE=3 SV=1
-QKGALYDAT-Y--KKEGSYYPVKTKLDVTRYGGFTSIKIAYYSIFKYDIRNKDKVK--ENIKIIPIPIYISQNIK-TDLNFAEGENIENLQ-LIYKKLN
IGALVKID-YYPYYVGGKTND-FAVQVLLSSDIERYLKEVVFVNFQISSEENIELYNTLLC-IFTHT---KNN--KYNDLAQAKNTFKNLSLEEQCKVLL
EILNLLTNKK-TDLSLINEKASRVKCGFLLNQKQFSIIEQSVTGLYEKEIKII-
>tr|F3A050|F3A050_9BACL CRISPR-associated endonuclease Cas9 OS=Gemella haemolysans M341 GN=cas9 PE=3 SV=1
-QKGGLFDAT-Y--KKEGVYYPLKTSVDVTKYGGFTKVKIAYYSIFEYTLVNKKGEE--KITRIIPIPIYVSQNIK-DDSEFGKGEEVKDFK-LKYRKLC
IGDLVKIN-NFFNFIGGKTND-FAVQVTLDTESERYIKTLSYQNWKITKEKNTELYNLLVE-IFIKK---KPN--KFNELNSIRNNFSSISLEEQAKVLL
EVLNLLTNKK-SDLKSINITAARGKISFLSNLSQFSIIEQSVAGFYEKEITII-
>tr|E5V117|E5V117_9BACL CRISPR-associated endonuclease Cas9 OS=Gemella morbillorum M424 GN=cas9 PE=3 SV=1
-QKGALYDAT-Y--KKEGTYYPLKTTIDVGKYGGFTKIKIAYYSIFEYTLDGKKGKQ--KITRIVPIPIYISQNIK-DDKEYAQ---GKDLK-IKYRKLC
IGSLVKIN-NFNYYIGGKTNN-FAVQVILDKDSESYIKELAYLNWKITEDKNIQLYDSLVK-IFIRK---TPN--KYTELLTVKNKFINIDIDEQVKLLL
EILNLLTNKK-FKLNEIGITASRGVCSFLSNQSQFSIIEQSVTGVYEKEKLII-
>tr|C5NZ04|C5NZ04_9BACL CRISPR-associated endonuclease Cas9 OS=Gemella haemolysans ATCC 10379 GN=cas9 PE=3 SV=1
-QKGGLFDAT-Y--KKDGVYYPLKTSVDVAKYGGYTSIGIAYYSIFEYTIVNKKGEE--KITRIIPIPIYISQNIK-DSTEFGKYEKIKDFK-LLYRKLC
IGSKININ-NYQYYIGGKSDE-FAIQVTLDKKSEKYLKILSYQNWKITKENNIELYNKLVE-IFTKK---KSN--KYNELNSIRNNFIKISVEEQAKVLL
EILNLLTNKK-SDLKSIDIKAARGKISFLTSLIQFSIIEQSITGFYEKEITII-
>tr|A0A091BLA4|A0A091BLA4_STREI CRISPR-associated endonuclease Cas9 OS=Streptococcus equinus ATCC 33317 GN=cas9 PE=3 SV=1
-QSHGLYNANPSP--KKGSKVNIKANL-PKNYGGYAGISNSYAVLVDATIEKGAKKKLTRIQEFQGISIIDREKYEKNKVEFLKGLGYKEIY--SIITLP
KYSLFELADGSRRMLASSTNNRGGNELVLPAKYIPLLYHANIHNTFYVEAEFKEIAEIILE---NKY---VNAK-NSSIIE----KALESSLDEICDSVK
GLFELVSLGSAS-FEFLETKVPRD-Y--PSSLLNATLIHQSITGLYETRIDLS-
>tr|E1QW44|E1QW44_OLSUV CRISPR-associated endonuclease Cas9 OS=Olsenella uli (strain ATCC 49627 / DSM 7084 / CIP 109912 / JCM 12494 / VPI D76D-27C) GN=
-GGGRYWGETIYSPK--KHEIPLKQG-DPNLYGGYSDLLYSYFLIYEA--SDVSSGE--RVLRFIGIPTSIAARMAN-QKEYVSQENLEHVR-MVR-KIM
KKQLIEVD-NCRLLVTAADAVTNATELAFSLDEMKIISTCACINGAKIGNAQDSFFDNLKRRGSDRC---ALLFS-QLKLDKLSQNFYMISSDDKSKILI
SILDRIRAKSNSD--LVGGAKHAAQMKFNNPASSFVLIDQSVTGMFERRTRIG-
>tr|U2U1P0|U2U1P0_9ACTN CRISPR-associated endonuclease Cas9 OS=Coriobacteriaceae bacterium BV3Ac1 GN=cas9 PE=3 SV=1
-QTGAYWEETIYSPLGKNLQIPLKQSYDPKKYGGTNTAFNAYFFAFVA--KDARGR---DKYFFEGVPVYLAKQLNEQPQDFANTKKCSTAK-ILRSKVP
LRQKFLLD-GTSFYLGGRTGNKNGVEFACGIDMAKMIDTAI-----LSQKELISIIQMLADTIERNS---DRQAS-LINFRRFDDKLRNIDAIAASRIIK
NLLNSMNGVKQSD--DLGGSKQSGFMQS----ERITWCYSSITGMFEQRVSFE-
>tr|F7UWL3|F7UWL3_EEGSY CRISPR-associated endonuclease Cas9 OS=Eggerthella sp. (strain YY7918) GN=cas9 PE=3 SV=1
-DSGAFWDATIYSPK--KGALPVKQG-PVEKYGSYSREQFAYFFVYKA--YNPKKKA--YRLEFEAVPVRVASAVETRENEYAKQAGLEFVE-VARPKVY
KYQLIELG-EDRLYITGKREVRNASQLAFSLDEIDLLKRLA-----TSSEERERLFDVLIEKYARYA---PRLAR-QLSVDSMSATFETLNAEEQLGILL
SLVEIANGKRNMD--SAGGSKNAGCMNPSSPGSNFTFIDQSVTGMFERRQRLE-
>tr|F2NB82|F2NB82_CORGP CRISPR-associated endonuclease Cas9 OS=Coriobacterium glomerans (strain ATCC 49209 / DSM 20642 / JCM 10262 / PW2) GN=cas9 PE=3 
-DHGVFWDATIYSPR--TAALPLKQG-NPSRYGSFSREQFAYFFIYKA--RNPRKEQ--TLFEFAQVPVRLSAQIRQDENRYARDQGLEFIR-IERSKIL
KNQLIEID-GDRLCITGKEEVRNACELAFAQDEMRVIRMLV-----VSRECVISLFNRILLHGDQAS---RRLSK-QLKLALLSEAFSEASDNVQRNVVL
GLIAIFNGSTNMN--DIGGSKFAGNVRIASPKVNVHLIDQSVTGMFERRTKIG-
>tr|U2VD49|U2VD49_9ACTN CRISPR-associated endonuclease Cas9 OS=Olsenella profusa F0195 GN=cas9 PE=3 SV=1
-ATGTFWDQTIYSPK--KLTLPLKRG-DPDRYGSYSREQFAYFFIYEA--RDLKHER--HILQFAQVPVRVAAHIAKDPSSYAVQANLAFVR-IVRRRIL
KKQLLELN-GDRLIITGVREVRNATEFAFSLDEETLIERCVIAKVGQLSADLNELFSSLVKRGPKLC---NRLYA-QLKLDKYLSKFDELTLTDKAKVVL
QLIAITNGSINMD--ALGSSKYAGCMQVNAPIGEVNIIDQSVTGMFERRTHIG-
>tr|R6I3U9|R6I3U9_9ACTN CRISPR-associated endonuclease Cas9 OS=Eggerthella sp. CAG:209 GN=cas9 PE=3 SV=1
-DTGAFWNATVYSPRGPKLALPLKKG-DPKKYGGFSSQQFAYFFVYEA--RDKKDK---QVFRFAEVPVWLASQIESDKIRYATAEKLKFVR-IERAKIL
KKQLIEID-GDRFILTGKKEMRNGRELALSQKETLNLIVAG-----DRGNASDAVFDAIVRQGDEIG---LRLYK-QLKIAEIAERYRSVGADAKVGAVM
SLLSSINASSNMN--MVGGSKYAGNLQPSDPETNFVIIDQSVTGMFERRTRIG-
>tr|A0A0B4S2L0|A0A0B4S2L0_9FIRM CRISPR-associated endonuclease Cas9 OS=Parvimonas micra GN=cas9 PE=3 SV=1
-GKGQLFNLTIKDRK---NIVANIPKDLAKKYGYFDSLNNSYFVLFKY--V-EKEK---EKIGFDGITIVDKEKLK-KNSERFL------AK-LI-RKIF
KNQKVLID-GYPYLLKSCNKDAIFKSLYLDENDLKFTRDAIFEKNNCIENEFDTLFLNLCD-IYKNY---KLPD-NVVEVKDKFEVFKNLELYNKSKLIK
NFLNYFKYDNN-DLIAIGIDSKA-----EDLIKDFVIVDESVTGLFAKKERLE-
>tr|D6LEV9|D6LEV9_9FUSO CRISPR-associated endonuclease Cas9 OS=Fusobacterium periodonticum 1_1_41FAA GN=cas9 PE=3 SV=1
-EKGQLFDLNPIRKN---EIIAIKPKELNEKYGYYKSLNPAYFIYVEH--K-EKNK---IIRSFERVNLVDVNKIK-DEKKYLI------PK-VI-KKVY
KRQVILIN-NFPYSIVALDSNLMLKPLFLERKYEKILKNAIFLEDNVKEIEFNEMYDKFLE-DYKNY---INN--KYSELVNVKEKFIKLNLFDKAFTLK
SFLDLFNRKTM-DFSKVGL---------VLSKNELHLLEESVTGLFVKKIKL--
>tr|A0A0M4SUA3|A0A0M4SUA3_FUSNV CRISPR-associated endonuclease Cas9 OS=Fusobacterium nucleatum subsp. vincentii ChDC F8 GN=cas9 PE=3 SV=1
-EKGELFNLNPIKKN---EIISIKPKNLNEKYGYYTSLKAAYFIYVEH--E-KKNK---KVKTFERITRIDSTLIK-NEKKYLV------PK-II-KKIY
KEQTLIID-SYPYTFTGVDSNKVKKQLYLEKKYEQILKNALFVEDNVKEIEFNEMYDKFLE-DYKNY---INN--LYTNFLNSKEKFKKLKLWEKSLILR
EFLKIFNKNTY-KYEIKDSQTKEKLFSFSSLGNNKELLEESVTGLFVKKIKL--
>tr|A0A0F6BWY9|A0A0F6BWY9_STRTN CRISPR-associated endonuclease Cas9 OS=Streptococcus thermophilus (strain ND03) GN=cas9 PE=3 SV=1
-QNHGLFNANLSS--KPNSNEN-KEYL-PKKYGGYAGISNSFAVLVKGTIEKGAKKKITNVLEFQGISILDRINYRKDKLNFLLEKGYKDIE--LIIELP
KYSLFELSDG--RMLASSTNNRGGNQIFLSQKFVKLLYHAKISNTIYVEKEFEELFYYILE---ENY---VGAK-NGKLLN----SAFQSSIDELCSSI-
GLFELTSRGSAA-FEFLG----VPRYR-SSLLKDATLIHQSVTGLYETRIDLA-
>tr|W1V0U5|W1V0U5_9FIRM CRISPR-associated endonuclease Cas9 OS=Veillonella dispar DORA_11 GN=cas9 PE=3 SV=1
-QSGALADAT-Y--KKDGAYIGMKTKFDVSKYGGMTKIKNAYSIIVQY--AGKKGE---VVKEIVPLPIYLTNRNT-TDQDYVAIPQAKDIS-IIYRKLC
INQLVKVN-GFYYYLGGKTNS-FAIQVIVSNEWIPYLKVLEFNNMRIVEEKNIEFFDYLVS-IYQKM---KGN--KAAELSEGYGLFKKMSLEEQSIHLI
ELLNLLTNQK-TEVKPLGITASRSTVGSISNQDEFKVINESITGLYSNEVTIV-
>tr|R5J5B2|R5J5B2_9FIRM CRISPR-associated endonuclease Cas9 OS=Peptostreptococcus anaerobius CAG:621 GN=cas9 PE=3 SV=1
-DKGPILNKVTH--KKNKKGFPIKSSLNLYKYGGYKDLNYSHYTIVRYNVYEKKGLD--IKYYMIPIPYYLCLCNI-NQHY-DYKKDVNNIE-IIVNELK
MGSLINID-GYNYYLGGSKPK-FAYQIILDKEIERCIKEIVA----INKNLNMKIYKYIVN-VFRNR---KWD--KGEYLNSTIEKFSGLSVESQCNVIL
RLINDMRGSNKGNFDELEMTISRAEIPQLSNVSSFKIINQSITGLFENEVTIV-
>tr|A0A095ZV18|A0A095ZV18_9FIRM CRISPR-associated endonuclease Cas9 OS=Tissierellia bacterium S5-A11 GN=cas9 PE=3 SV=1
-QRGQFFDATIQ--KKNMLVLPLKGSLDTSKYGYYVRPSGMSFMVVQH--E-VKGK---SRVTIEPALLVYKNKLK-SEDKYCE------PK-VLFKNIK
FGSKILFD-GYPFLLKGRTEN-IAQSLFLGNQELKILKRVTISDDIITDEEWTTLWKSVVE-KFRNR---LGTLQDQETFLSLLERFLQFSTEEKTRLLL
QVISFS--GNTTDLRLIGGSSGTGTIKTITD-HSVILINESPTGLFTNRTVLN-
>tr|D6KPM9|D6KPM9_9FIRM CRISPR-associated endonuclease Cas9 OS=Veillonella sp. 6_1_27 GN=cas9 PE=3 SV=1
-QKGQLSDIN-T--KKADIYLPIKANMQNMKYGGYSDIKNAYYTIIEY--SDKKNN---SIKAFIPIPIFIATKTL-TKQEYIKLPKANNLR-IIYKKVY
NDQLLKID-GFNYYLGGRSND-FAIQLIVPLEIQFYIKLVEFTAIIITLEYTQKLFDYLVS-IYLKM---RGN--KLTDVNNGRKQFIKLSLEERCKALA
ELLNIFTNMN-KSLSTINVSASRKVVNFISSLDEFKIVNESITGLYSHEITIV-
>tr|E1LBR5|E1LBR5_9FIRM CRISPR-associated endonuclease Cas9 OS=Veillonella atypica ACS-134-V-Col7a GN=csn1 PE=3 SV=1
-QSGALADAT-Y--KKDGAYIGMKTKFDVTKYGGMTKIKNAYSIIVQY--TGKKGE---EIKEIVPLPIYLINRNA-TDIDYVKIPKAKDIS-IKYRKLC
INQLVKVN-GFYYYLGGKTND-IAIELVVPHDIATYIKLLDYDLLRLSNKVGIDVFDYFMS-LYMKM---KGN--KVDELSSGRSKFIKMTLEEQSIYLL
EVLNLLTNSK-TDVKPLGITGSRSTIGVIHNLDEFKIINESITGLYSNEVTIV-
>tr|W3Y2C1|W3Y2C1_9FIRM CRISPR-associated endonuclease Cas9 OS=Veillonella sp. AS16 GN=cas9 PE=3 SV=1
-QKGALSDAT-Y--KKGGAYIGMKTKFDVSKYGGRTSIKNAYSIVVEY--TGKKNE---IIKEIVPLPVYLINRNK-TDQHYIVIPQAKNVS-IIYKKLC
INQLVKVN-GFYYYLGGKTNN-FAIQVVIADEWIPYLKVLEFDVMRILEERNVEFFSYLVG-IYSKM---KGN--KAGELATSLEIFVNMSLENQCIYLM
ELLNLLTNKK--DVKPLGITASRGTIGSVSNQDEFKIINESITGLYSNEVTIV-
>tr|R5FLM1|R5FLM1_9ACTN CRISPR-associated endonuclease Cas9 OS=Eggerthella sp. CAG:1427 GN=cas9 PE=3 SV=1
-TSGAFWDATIYSPKKKKLSLPLKKG-DPQKYGSYSREQFAYFFVYEA--KKIKKKEETKEYVFASVPVQVAALVAADPNEFAKERGLKFAK-IVREKVY
KYQLIEVN-DERFFVTGLRTVRNGLQIAFSEQDRNIV-SGI-----SSNNNLLDIYDKITNRYALYA---SRFGK-LLNLSGYRENFIQASLEDQERVVL
ALISLFNARTNMD--AIGSSKTVGNMSMAMADNRFAFIDQSVTGMLERKTYL--
>tr|R7CG17|R7CG17_9ACTN CRISPR-associated endonuclease Cas9 OS=Cryptobacterium sp. CAG:338 GN=cas9 PE=3 SV=1
-TSGAFWKETLISPRGKNLSLPIKKG-DPRKYGGYNEQKFAYFFVYEA--VKIKKKGEVKEYVFAAVPVQVAAIVARDPNGFAKARKIKFLR-IIREKVY
KYQLIEVN-GERLYITGLKSVRNARQIALSQDMTTVFLKAI-----VAEDELKSLFEEIVQRYRLCA---NRLGN-QLKIFSLSDSFNSANSESKKRALV
SLVAIIDAKTNKD--GIGSGKAVGNMRLSNSKNHFAFIDQSVTGMFERKTYL--
>tr|D6E761|D6E761_9ACTN CRISPR-associated endonuclease Cas9 OS=Gordonibacter pamelaeae 7-10-1-b GN=cas9 PE=3 SV=1
-THGAFWDATIYSPRGKTLSLPLKRG-DPRKYGSYSREQFAYFFVYEA--VKPKKKQ--RVLEFAPVPVRVASALANDPDDYARAEGLVFER-IRRRKVY
KYQQIIVG-DSRLYVTGREEVRNARQLAFSQDETKLICRIE-----CEEGELLDLFRSMQRKYLACA---PRLAR-LMKVAEMEEGFIAATASGKREVLL
SLTSIAAAHRNSD--PIGRKGSSGQMKISTNG--ILFVDSSVTGMFERRCRLG-
>tr|E8KPA4|E8KPA4_STRSA CRISPR-associated protein, Csn1 family OS=Streptococcus sanguinis VMC66 GN=csn1 PE=4 SV=1
-KKGAFYNQNPVGKF--NNRYPLKTKCDTSIYGGYGPMNSTLSIIIIA--ERFNEKKGETVKEFHDIFIIDYEKFNNNPF-FLNKKNNINRV-LGFYRIP
KYSLMQKIDGTRMLFESKLNLHKATQFKLTKTQNELFFHMKLLTNS-----HKEEFDNISNQLSAFS---QKMLGNTTSLKNLIKGYNERRE-ETIKYYD
KMFSFVKSGAPKI--FFDNKYTVARMRPDKRLLNATLIHQSITGLYETRIDLS-
>tr|M3INT0|M3INT0_9STRE CRISPR-associated endonuclease Cas9 OS=Streptococcus tigurinus AZ_3a GN=cas9 PE=3 SV=1
-KKGAFYKQNIIPN---DKRFPIKNKYDPKLYGGYYERNSALSVFIIG--QSFNKNNKKVVKEFYDINIIDYPLFNTDPM-FFNTKNNLQSV-QAFYKIP
KYSLIQKNDGTRMLFESTTNFHKATQFKLTEAQNELFFHMKLLTKT-----HKNEFDNIVNGLFGYA---ERQLGSKSLFTQAHEAYKLRNE-ETIRYYD
RLFSLTKSGTSSY--GLFEAPKLRNVVYTKDESNATLIHQSITGLYETRIDLS-
>tr|E0Q490|E0Q490_9STRE CRISPR-associated endonuclease Cas9 OS=Streptococcus sp. oral taxon 071 str. 73H25AP GN=cas9 PE=3 SV=1
-KKGAFYNQNPVGKL--NNRYPLKTKSDTSIYGGYGPMNSALSIIIIA--ERFNEKKGETVKEFHDIFIIDYEKFNNNPF-FLNKKNDLNRV-LAFYRIS
KYSLMQKIDGTRMLFESKSNLHKVTQFKLTKTQNELFFHMKLLTKS-----HQNEFDNIADRLSNYS---QKMLGETKSLQTLINGYNERNE-ETIRYYD
KMFSFVKSGAPKI--FFNDKYTVPRMRPDRKMLDATLIHQSITGLYETRIDLS-
>tr|R7N9S8|R7N9S8_9FIRM CRISPR-associated endonuclease Cas9 OS=Eubacterium sp. CAG:76 GN=cas9 PE=3 SV=1
-NTGAFYSETKYPREG-SKLVPLKQGEDARKYGGYKGGEKAYFVLVKY--CIEKALKKEYHMEFVEIPVYIARGIKNKDIDYVCKNSVADVE-ILRNKVP
KYQMIIGENGEEYYLVSATEVINSKQFVLGGANQQYNRLLNYIKYG-LDEQLIGLYNLLIAKIKDEY---KGFSKEAVRIQENNS-FDKL----KKEFIA
EMIKLVQPDSDYYLGATGLSNRMGRKTGKVG-KKITLVDKSVTGLYERRTTFE-
>tr|E2NV81|E2NV81_9FIRM CRISPR-associated protein, Csn1 family (Fragment) OS=Catenibacterium mitsuokai DSM 15897 GN=csn1 PE=3 SV=1
-KSGQLFNLTVLSNDVTKAVVPVNKNRDVHKYGGFSGLQYTIVAI-----EGQKKKGKELVKKISGVPLHLKAASINEK-NYIEKEGLSDVR-IIKDNIP
VNQMIEM-DGGEYLLTSPTEYVNARQLVLNEKQCALIADIYAIYKQ-DDILMIQLYIELTNKMKVLY---PAYRG-IAEKFESMN-EN--SKEEKANIIK
QMLIVMHRGPQNGNIDFKISDRIGRLKTNHNLNNIVFISQSPTGIYTKKYKL--
>tr|R7GMQ9|R7GMQ9_9FIRM CRISPR-associated endonuclease Cas9 OS=Catenibacterium sp. CAG:290 GN=cas9 PE=3 SV=1
-KSGQMFNLTVLPNDTTEAVIPVNKNRDVNKYGGFSGLQYVIVAI-----EGKKKRGKKLVKKISGVPLHLKAASLDEK-KYIEKENLTDVK-IIKDSIP
VNQMIEM-DGGEYLLTSPIEFVNGRQLVLNEKQCALIADIYAIYKQ-DDVLMIQLYIELINKMKALY---PAYQS-IAEKFESMT-ED--SKEEKADIIK
QMLIIMHRGPRNGKIDFNVGDRIGRKNKSLDLERVTFVSQSPTGIYTKKYKL--
>tr|A0A0R2HM97|A0A0R2HM97_9FIRM CRISPR associated protein OS=Kandleria vitulina DSM 20405 GN=IV49_GL000127 PE=4 SV=1
-NNGTFFNVTVLPNDNTLATVPVNKYRNVNKYGGFSGVNSFIVAI-----KGKKKKGKIEVNKLTGIPLMYKNADEEIK-NYLKAEDLEEVQ-IGK-EIL
KNQLIEK-DGGLYYIVAPTEIINAKQLILNESQTKLVCEIYAMKYK-DSEKIIDLYRLLINKMELYY---PEYRKQLVKKFEDRY-EQ--SIEEKCNIIK
QILATLHCNSSIGKIDFKISTTIGRLNGTISLDDISFIAESPTGMYSKKYKL--
>tr|R7I2K1|R7I2K1_9CLOT CRISPR-associated endonuclease Cas9 OS=Clostridium sp. CAG:411 GN=cas9 PE=3 SV=1
-NTGEFYKQTINAKPN-TKLLPIKK-GSVEKYGGYQGGEAAYSCLVRY--QQGRKT----KLSLEKISVIIAKKIAEKEVRYLK-LGVEEIV-ILRKKVM
KNQLIEDSDGNRFYLTAATEVVNAKQFILDGKHQHLLRTIAIMEKG-LENSMDELYAYYRMKIQQQY---PAYESIVKKIVESHV-YESLAVQEKGKFLI
QLLRLTEANAECDLKDGRLADRIGRKNHTIK-EGIKFIDQSITGLYERYMTV--
>tr|J0DFD8|J0DFD8_9BIFI CRISPR-associated endonuclease Cas9 OS=Scardovia wiggsiae F0424 GN=cas9 PE=3 SV=1
-VTRALYDETRYGHKS-AKSIKFDNLRDTSLYGGFSGASTAYMMLVEY--KKKNK--------LVSITAQEASLLAVADQDGILSHGLSGAK-ILLPKIV
TGQLLDY-SDALVTLQSASELNTARQMWLPRNDYNDIDIILSKDIEHVLRRIQKLFEAVFR-AESQF---PLHQLSKDQQEEILRDPQNYGFGSAVKLLG
GLLKALHANAENEFKKFGFSPRWRRISNFTLSDSDTFIYQSPSGIFEQRVTVK-
>tr|A0A0F4G1L4|A0A0F4G1L4_9BIFI CRISPR-associated endonuclease Cas9 OS=Bifidobacterium angulatum GN=cas9 PE=3 SV=1
-NFGPLYNETRYGAGG-RDGIAFGKNKDTSLYGGFSSAKVVYSVLIEL--KKKVQ--------LVNITMQEYAILGDRPSV--AKKEYSKAR-FLLRHIP
QMQLIRY-NNAYMVIKSATELNNARQLWIDHRVYDALDDYLKGVSR---VDTVTVWDMLFK-VEKGY---PLHVIERNVLDDARVKFMELSLAEQIDVLG
LIVIALHADPRRNLRIVGLPSEWKRIRSVSFSDNDEFIFQSPSGLFEKRVTVA-
>tr|A0A087BJ94|A0A087BJ94_9BIFI CRISPR-associated endonuclease Cas9 OS=Bifidobacterium merycicum GN=cas9 PE=3 SV=1
-SFGALYNETRYGTSG-VNGIPFDKHKDTALYGGFSSAKTVYVVLIEA--KKKTR--------LVNITMQEYAELGDHPSA--KKPEYGKAR-ILLRHIP
PMQLIRY-GGALVTVKSATELNNAQQLWLPYKEYCLFDDVISAIDV---ARLCQMLDVILD-IQKYY---PKQRFDETGLSAFHNAFNEVSAEDKKRIVG
EMVGMLHADAKNNLKALGMSGRWGRMSNYTFADSDEFIFQSPSGLFEKRISVG-
>tr|E3ELL7|E3ELL7_BIFBS CRISPR-associated endonuclease Cas9 OS=Bifidobacterium bifidum (strain S17) GN=cas9 PE=3 SV=1
-DFGALYDETRYAATG-IKGIPFDGAKDTSLYGGFSSAKPAYAVLIES--KGKTR--------LVNVTMQEYSLLGDRPSA--KKSEYAKAN-ILLRHVP
KMQLIRY-GGGLMVIKSAGELNNAQQLWLPYEEYCYFDDLSGKGSL---DDLKKLLDSILG-VQCLY---PWHRFTEEELADLHVAFDKLPEDEKKNVIT
GIVSALHADAKTNLSIVGMTGSWRRMNNYTFSDEDEFIFQSPSGLFEKRVTVG-
>tr|R5ZG15|R5ZG15_9CLOT CRISPR-associated endonuclease Cas9 OS=Clostridium sp. CAG:568 GN=cas9 PE=3 SV=1
-LKQGFFKKITLKTKNSDKLFPLKQYVDVNKYGGYSDMITPYFMLVQS--EGKKGK---HIYSLESIPTIYLKSFKKKEENYLSKNKLKNPV-VISDKLL
MRTIVKIP-SNLSLLSGRTGNNILSELILPIEWKNYYRKISLLGTNVEHDKNNRFFSYLINPIFEGL---PKTSCSFIKLESKYDEFCSLNTLEQAKIIA
TIIKLLSCKSVQKLS--GLPSSLGALISKALTEGTIISKESSCGLKENIIFVV-
>tr|A0A0R2AFH9|A0A0R2AFH9_9LACO CRISPR-associated protein, Csn1 family OS=Lactobacillus agilis DSM 20509 GN=FC14_GL000697 PE=4 SV=1
-NSGAMFKETIYPVN--QKLIQKKNDKPVDIYGGYSNNYDAYLSIVRL--EDK-KG---IKFRVVGIPMRNKAELDLAKEEIVD--KKKTFR-IILPKVH
FKQLVEDD-SGKFMLGSAAYPYNAKQLVLSVKSIESLANKD-----ASDRELVAVYEEILN-VNDKF---TLYD-FRNKLTSSKDKFVEL---DKVTELL
DILDGLHANPVVKLKIISG-SPFGFLQRIVLTENAKLIYQSPTGIFERVVYLR-
>tr|I6T669|I6T669_ENTHA CRISPR-associated endonuclease Cas9 OS=Enterococcus hirae (strain ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCI
-QKGGFYKETVNS--KPDKLIERKNNW-VTKYGGFGSPVIAYAIAFVYA--KGKTQK--KTRAIEGITIMEQAAFEKDPTTFLKEKGFPQVT--EFIKLP
KYTLFEFDNGRRRFLAS----HKGNPFILSDQLVTLLYHAQYDKITYVNSDFSAILTEVLA---EKY---TLAD-NIERIQE---LYEENETSMIAQS--
QLLQFNAIGAPA-FKFFGVTI--KRYT-LTEIWDATIIYQSVTGLYETRIRMG-
>tr|V5XLV7|V5XLV7_ENTMU CRISPR-associated endonuclease Cas9 OS=Enterococcus mundtii QU 25 GN=cas9 PE=3 SV=1
-QKGGFYKETINS--NPEKLIPRKASL-PLKYGGYGSPLVAYTVIFIFE--KGKQKK--VTKGIEGITVMEQLRFEQDPREFLKTKGYEGVK--QWLILP
KYILFEAQGGYRRMIAS----HQANSLILPENLVTLLYHARYDEINYVNEGFNDIFDFISD---VRY---ILAP-HLEKIKV---AYEKNDLKEMIDA--
SLLKFTLFGASV-FKFFDIKI--KRYK-LTDIWEATIIYQSVTGLYERRVEVR-
>tr|H7FYD8|H7FYD8_9LACO CRISPR-associated endonuclease Cas9 OS=Lactobacillus salivarius SMXD51 GN=cas9 PE=3 SV=1
-KNGAFYDQTKYNAK--VNLIPIKKNKPTNIYGGYKGKVSSYMMLVKI--RKK-KE---VIYKFVGVPRLWTDELDLKDTEIA-SKTEQDFE-VILDKVY
YGQLIIDG-NQKYTLGSSEYKYNAMQLHLSKHALEVLAKEN-----ITDKDLVSVYEEILS-VNKYF---ELYD-FRQKLNEGLEIFRKLKQVGKFEVLN
RILMGLHANAMIDLKVLGIKTKLGQMQVIKLSPDAKLIYQSPTGIFSRAVRVK-
>tr|A0A0R2JSC5|A0A0R2JSC5_9LACO Uncharacterized protein OS=Lactobacillus lindneri DSM 20690 = JCM 11027 GN=IV52_GL000135 PE=4 SV=1
-NHGNLFKQTLYPSHKMKNLINPKENRSSDIYGGYSSETGAYVSLIKV--FKK-NK---IENKIIKIPLLYIDKLNQA-NN-FIKDDSNKFD-ILSEKIF
LNQLVIDG-DELFTISGSGDRQNAQQLILSDKSLKILSKNIV----ISKNDLIIIFNEIID-ICKYM---KMYE-SD----ETKAKFEEI----MLKIIN
DLLLGLHANASRNLSSIGLSPSFGRFFSIKLSENAKFIYQSPTGLFSRKVKIS-
>tr|A0A0R2CL57|A0A0R2CL57_9LACO Uncharacterized protein OS=Lactobacillus florum DSM 22689 = JCM 16035 GN=FC87_GL000484 PE=4 SV=1
-NEGALYKQTIYKAPKNRSLINTKKNRPSDIYGGYSQSVTAYMSLVFF--KNT--------FKLIKMPLVAANAIKSL-STILKL-GSNEFK-VLIPKVK
MNQLIKE--GDSLYTVVGVYKHNAQQLILSDNSMGIITKPIE----ICDSDLDSVFNELVD-IDKYL---NLYK-KL----TIKEKFYAL----KFKCIS
DILVGTHCNAGRNLKIIGLSSYWGMFSGLKINENSQLIYQSPTGLFEHRVKVS-
>tr|W9EE99|W9EE99_9LACO CRISPR-associated endonuclease Cas9 OS=Lactobacillus florum 8D GN=cas9 PE=3 SV=1
-NEGALYGQTLYPAPKTRNLINSKKNRPSDIYGGYSNENGSFLTLVKL--KKG-SK---YDYRLVAVPVSKISEIKSE-LQFLKSGKYRDFQ-VVLSKIL
INQKVIDD-GMIFTIGSKSYKHNAKQVVLSDNSIQIVSTLSI----SDKEKLITVFDEIVD-TSKYL---PWYK-VE----KTKMLFRQM----MKKIID
NSLIGLHCNASIDLGKVGLSKYWGRFVLISLTVDAQLIYQSPTGLFEHRVKVS-
>tr|G2KVM6|G2KVM6_LACSM CRISPR-associated endonuclease Cas9 OS=Lactobacillus sanfranciscensis (strain TMW 1.1304) GN=cas9 PE=3 SV=1
-NHGALFKQTLYPSPKKRQLIKPKDNRPTDIYGGYTHEERKYMSLVKV--IGK-KD---NEYRMANVPLLKINKNNIK------QFSNKKFE-IVLPKVL
KNQLFSEN-GALFVIGSKGYKYNANQLVLSDLDMKLLNDLSNKS--IDEVTINQLFKNIVD-TNKYM---PLYE-LN----EVVEKFNNL-----KKTIT
DFLLATHANPTMNLKNIGLPSYFGRFTSIKLSENANVIYQSPTGLFSRKVKIS-
>tr|A0A0R2DR00|A0A0R2DR00_9LACO Uncharacterized protein OS=Lactobacillus senmaizukei DSM 21775 = NBRC 103853 GN=FD13_GL002020 PE=4 SV=1
-SAAEMYAQTIFKAS--KVLIPTKNDRPTAIYGGYTKRRNGYLAILKI--TEK-KA---ETYRVVGVPTLYMSQLAARSHSLMA-SKVVSFE-VVVSHVH
LNQLVRDT-AHYFGLGPFRYVRNFHQLVLPFKDQEILVKRTT------DEELNTVFEDICW-VENYF---AVFD-FRNALKKSIDKFEQLVTQGKKEVLA
FVMQGLHANASYNLKSLGIKTPLGQLQLFMLSRDAELIDESPTGLFRRIRRLK-
>tr|B4U3U9|B4U3U9_STREM CRISPR-associated endonuclease Cas9 OS=Streptococcus equi subsp. zooepidemicus (strain MGCS10565) GN=cas9 PE=3 SV=1
-QTGGFYKESILS--NSDKLIPRKNNW-TRKYGGFDSPTVAYSVLVIAK--MEKGKAKKPVKEMVGITIMERTAFEENPVVFLEARGYREIQEHLIIKLP
KYSLFELENGRRRLLAS----ASGNELFLPVDYMTFLYLAAYHELTFVDHYFDDIIQMIND---ERH---ILAS-NLEKINH---TYHNNV-NERAEN--
NVFTFVALGAPA-FKFFDA--TIKRYT-TKEVLNATLIHQSVTGLYETRIDLS-
>tr|A0A0R1V7X0|A0A0R1V7X0_9LACO CRISPR-associated protein, Csn1 family OS=Lactobacillus gastricus DSM 16045 GN=FC60_GL000538 PE=4 SV=1
-KTGDLFNVTVYSRK--KTLIPIKQDKPINIYGGYSGNNDAYMAIVKL--PGKKGKP--DTYKIVGIPLRFAGELEAKQLAVITTKVVDDFE-VVLDRVP
YRQLFKDS-DKWFMLGSAAYQYNAKQLVLNNDDVKLLNEQGKKL--KLSSALNDVFDHIIQ-MNSKF---GLYD-FRTKLTEAASIFYDLVTDGKLEVLD
NILIGLHADPSFNLKQLNMSTPFGQMQTVVLNGNSTLIYQSPTGLFERRVKLK-
>tr|A0A0R1MEL8|A0A0R1MEL8_9LACO CRISPR associated protein OS=Lactobacillus hordei DSM 19519 GN=FC92_GL000539 PE=4 SV=1
-RQGAMFKQTVYSAA--KKLIPVKEDRPIDIYGGYTNNNDAFLAIVKV--TKK-K-----QYMVVGIPQRAVVKLNAAKQNVIKTQKLENFE-IVVSKTL
YRQLIIDG-DQKYMLGSSAYKYNAKQLVLSEYALEVLDRSI-----YTTVDLDNVYDEILA-VDKYF---SLYD-FRQKLHESRKIFTELLKSGKRETLN
EILEGLHANATKDLKSLKFSTPLGMIQYIILSENAILCYQSPTGIFERRVTLK-
>tr|A0A0R1X611|A0A0R1X611_9LACO CRISPR associated protein OS=Lactobacillus acidipiscis DSM 15836 GN=FC65_GL000457 PE=4 SV=1
-RQGAMFKQTIFPAA--SKLIPIKNDKPTAIYGGYTNNNDAYLAIIKL--AKT-G-----QFKVVGVPQRAIVKLKAYDKKVLETYQVEKFK-IVVPKVP
YRQLVIDG-DQKFMLGSSTYKYNAKQLVLSENAIKILDKKS-----YKSSDLDTVYDEILS-VDRYF---SMYD-FREGLHNGKKYFQRLKENGKFKLLN
EILIGLHANPSFNLKSLGISTPFGMMQFISLSENAILCYQSPTGIFERRVALK-
>tr|A0A0R2HZC9|A0A0R2HZC9_9LACO CRISPR-associated protein, Csn1 family OS=Lactobacillus secaliphilus GN=IV45_GL000634 PE=4 SV=1
-KTGPLFDQTIYPAG--SRLIPIKKDRPTDIYGGYSSSTDAYMSLIRV--PDK-KE---DKYKVVGVPSRSLASLNAEKRQVIA--QKKEFQ-IIIPKLR
YRQLIIDG-GLKYTLGSSAYQYNARQLVLSEKSMEVLVTDFK-V--KQNQKLIAVYDDILD-VNRCL---PLYD-FRKALNGARDKFVQLEEAGKVEILN
EILLGLHDDASTNLKPLGIKTPFGMLQTITMSSNAVIVNQSPTGLFEHRIYLK-
>tr|R5MT23|R5MT23_9MOLU CRISPR-associated endonuclease Cas9 OS=Mycoplasma sp. CAG:956 GN=cas9 PE=3 SV=1
-RTGKLYKETIYKRG---GNIKIKE-NPTETYGGYSNMETSYLTLVKY--GN-K-------TKLIGIPMSIANNKDVKV-DFIKLKSLDNIV-ILKDNIP
YDVSINYKNQDVYVK----------GYSTANKNCELSNAHQKIKKDNAITFINYLFEI-----KIEF---PLFSKEITKIQDNIN-LTECSFEQLANIIK
QLLIIYHCNSKN---EFGLSDRIGRLSGNVT--GGDFIFTSVTGLKEKTASYD-
>tr|A0A0R1W1T1|A0A0R1W1T1_9LACO HNH endonuclease family protein OS=Lactobacillus concavus DSM 17758 GN=FC15_GL001662 PE=4 SV=1
-NGGALYNMTVYGKAAKRKLIPIKADKPTELYGGYTSRKLAYMAIVKT--KKG-KK---EQYQVTGVPVSALTTLRFKEDEIVR--EKTEVE-IIVPKVL
FNQLIVDE-KCRFMVGSDTYRYNAQQLVLSADDLEIINASHDIQTIDYSQQLDQVYQNILT-VDKHF---PMYD-FRTKLHDIYEQYIELTTLGKHTIII
RILQGLHANATVDLKQLGIKTPFGFMQQIVVSPDAQLIYQSPTGLYERRVRLG-
>tr|U7PCQ1|U7PCQ1_STASI CRISPR-associated endonuclease Cas9 OS=Staphylococcus simulans UMC-CNS-990 GN=cas9 PE=3 SV=1
-TESAFYKQSAFSPKD-----------DKNKTAIYKEMKNKRGIVVSY--TYVKKDQELIGYGVFNETVFEY--VNNADVKIVRKLDIKKAQ-YLF-SIN
KGDALLVN-GHPFLFVSAKERINGKQLEFDINMQRRLKKAL-----MTEQEKVGVYNQFAEKVVQEY---ENSLGAKT--RNEKLELIRNSNEALIQCLE
-VLKMTKVSAERVKL----KIRWGSQTPIDINNKAKIMYNSITGLKQTRLKSI-
>tr|A0A0R1TGJ3|A0A0R1TGJ3_9LACO Uncharacterized protein OS=Lactobacillus paracollinoides DSM 15502 = JCM 11969 GN=FC17_GL003239 PE=4 SV=1
-SFGAMYKQKILKATGGFKLVPTKRNRPVDIYGGYTGQTAAYLTIVRV--YSK-KT---SELRVLPIYTNKVQQIEAMTQKVIAEIKIPEFD-VVIPKVL
LDQLVIDD-PHRFRLGTDTYYHNSQQLFLPLSMQRQLMDRED------DKVYLDIFNDVLK-VDSYF---NLYD-FRAALQKSKKAFEQLKKKGKRSILK
EIFIGLHANATLNLKQMGIKTDFGKLQKLRITENCKIIHQSPTGLFERIVPIK-
>tr|A0A0R2N0I6|A0A0R2N0I6_9LACO Uncharacterized protein OS=Lactobacillus saniviri JCM 17471 = DSM 24301 GN=IV56_GL001823 PE=4 SV=1
-NMSALFDQTIYPRPTKRKLIPTKLDKPTDIYGGYSSAKTAYMAVMRV--QTK-KG---TEYPVFNIPVSIASQLNITDQQFIIKKLYESGD-VILSRVA
LGQRFTDK-VF---LISNMEVQNPQSLWLGRASQQRLT-REEGN--KPETSLADIYQQILK-VDRYF---LAFN-QRQKLLGTLDQFTSLTDQNQRSIIA
RVMIVLGKGSREKFPEFGL-SALGRLVRITLSEDAQIIYQSPTGLFERRVALK-
>tr|M4KKI8|M4KKI8_LACPN CRISPR-associated endonuclease Cas9 OS=Lactobacillus plantarum ZJ316 GN=cas9 PE=3 SV=1
-NYGAMFDQTLLKAS---RLIRKKQSFDTAIYGGYTGKTLAYMAIVKV--STK-KD---VQYQVVGVPTTMVTQIELEQQKVIENKKMLTYE-VLLPKVR
FEQVVRDR-THRFALGTDTYYHNIQELYLPLTLQRAFLGKQESE--QLNQNLLTVFDATLA-VNRYF---PLYE-FKKILNSARDQIELLLVLGKQGILT
NMFIGLHANASYDLKVLGVKIDFGKLQVIKLTGDAEIIYQSPTGLFERKIALK-
>tr|A0A0R2DGS6|A0A0R2DGS6_9LACO HNH endonuclease family protein OS=Lactobacillus rennini DSM 20253 GN=FC24_GL001742 PE=4 SV=1
-NRGPMFKQTIYKAEGSKQLIPTKKNRPTELYGGYTNKETAYLCLVKE--PHK-KG---DIYRICSVLNMWLTELDIA-DELLTIPVVKPFK-VVIPKIL
INQRFFSR-GQELTVASPMYMHNEQELFLNKKTIKLLNGQLKNEA---HELAPKIYQQILD-VNDYF---PLYD-FRDTLNASKEIFVNLSQSGQKSILN
KILIGLHANAARKLTELNFKSDFGLLSQIAFSPDDQIIYQSPTGLFERRVTLK-
>tr|A0A0R1RFJ4|A0A0R1RFJ4_9LACO CRISPR-associated protein, Csn1 family OS=Lactobacillus oligofermentans DSM 15707 = LMG 22743 GN=FC70_GL001116 PE=4 SV=1
-NSGAMYDQTLYPAKGAKQLIPKKDDMPTALYGGYTGSKDAFMSIVRL--KKK-DE---VYYKVIGIPVRIADSVQH--GQFIETRKVEWFE-LVLPKVL
FGQAVFDG-GQPFMLGSSTYPHNLRELVLTKDSVKKIA-GK--ES---NKSYLDAYDEIME-MNKYF---PLYD-FREKVIEGRSKFIDLVQVGKSTIID
RMFIGLHANAARDLKNIGITTPFGFMQQIKLTKDTVVLFQSSTGLFERKVALK-
>tr|A0A0R2DIR3|A0A0R2DIR3_9LACO Uncharacterized protein OS=Lactobacillus floricola DSM 23037 = JCM 16512 GN=FC86_GL000511 PE=4 SV=1
-RHGNLFKQTIFKAG----LIPVKNNRDIAIYGGYKSKQVSYYALISL--HNK-KR---QK-RLVAVYLIDIQKLQLNESTII-HNIKPEFD-ILADKIY
QNQLIIDN-NRPFRIE--GDFKNDRQLYLPLQYQRWLASKET------DEKLNRIFDHICE-LADYF---PLFA-CDK-LLDNRDKFYQLIAEGKLSVID
KLLVAMHADSRNNLAVIGLSSSWGRFKLNEIGTSVQLIHQSPTGLFKRIQRFN-
>tr|A0A0R1RRH5|A0A0R1RRH5_9LACO HNH endonuclease family protein OS=Lactobacillus fuchuensis DSM 14340 = JCM 11249 GN=FC69_GL001629 PE=4 SV=1
-NHGALYNQTLYKAKGGRQLIAAKENRPTAIYGGYSGKTVAYMCLVRI--TEK-KG---DFYRICGVQTAWVDELEIE-DALLTVTVVKPFE-VLLPKIL
INQRFYDG-GQELTLASATYKNNAQELVLDKKAVQVLNGQLKAEL---EAQATVVYDQILE-VQKYF---PLYD-FREKLFVGRDKFNELIQVGQKTILD
RILIGLHANAAMDLKALNMSTPFGKLQKISLSPETQIIYQSPTGLFERRVALK-
>tr|A0A0B2XHU2|A0A0B2XHU2_LACCU CRISPR-associated endonuclease Cas9 OS=Lactobacillus curvatus GN=cas9 PE=3 SV=1
-NSGALFNQTLYAAKGGKQLIPAKQDRPTALYGGYSGKTVAYMCIVRI--KNK-KG---DLYKVCGVETSWLAQLKLT-DQKISVKVVEDFE-VIAPHIL
INQRFFDN-GQELTLGSATYKHNEQELILDKTAVKLLNGALLTQS---EELAEQVYDEILD-VMHYF---PLYD-FRAKLSAGKAAFMKLVQVGQQVILD
RVLIGLHANAAVDLGVLKISTPLGKMQQISLSPDTQIIYQSPTGLFERRVALR-
>tr|A0A0R1LCE0|A0A0R1LCE0_LACCU HNH endonuclease family protein OS=Lactobacillus curvatus JCM 1096 = DSM 20019 GN=FC08_GL000879 PE=4 SV=1
-NSGALFNQTLYAAKGGKQLIPAKQDRPTALYGGYSGKTSAYLCLVKI--KNK-SE---YIYRIFGVNTSWSSELKIQ-DKLLTVPVTKDFK-IILPRIL
INQKFYSR-GQDISIASEFYLHNEQELVLDKSDIKILNGAIVNNS---NKQVINLFNHILE-VNQYF---PVYD-SREVLNSSKEIFENLINVGQKTILN
RILIGLHANAARKISELGFKNDFGLLTQITFTPDTQIIYQSPTGLFERRVALR-
>tr|A0A0R1WWN2|A0A0R1WWN2_9LACO HNH endonuclease family protein OS=Lactobacillus graminis DSM 20719 GN=FC90_GL000954 PE=4 SV=1
-NSGALFNQTLYAAKGGKQLIPAKQARPTALYGGYSGKTVAYMCIVRI--KNK-KG---DLYKVCGVETSWLAQLKLK-DQKISVKVVEDFE-VIAPHIL
INQRLFDN-GQELTLGSATYKHNEQELILDKTAVKLLNGELLAQS---EELAELVYDEILD-VMHYF---PLYD-FRAKLLAGKTAFMQLVQITQPIVLK
KILQGLHADAGRSLKELGMTTDFGMLQKITFTPDTQIIYQSPTGLFERRVALR-
>tr|A0A0R1SN52|A0A0R1SN52_LACSK HNH endonuclease family protein OS=Lactobacillus sakei subsp. carnosus DSM 15831 GN=FC71_GL000651 PE=4 SV=1
-NTGALYNQTLYSAKGGKQLIPAKQDRPTALYGGYSGKTVAYMCIVRI--KSK-KE---DTYKVCGVKTSWVAELELS-DAKLMIQVTEDFE-IIVPRVL
INQRFYDN-GQEITLGSATYKHNEQELMLNKKAVKLLNGQLLVEA---ETLAPQVYDEILK-VMKYF---PLYD-FRTKLKMGKEQFIKLIHVGQQTVLD
RILIGLHANAAVDLSTLKVTTPFGKLQQIALSLNTKIIYQSPTGLFERRVALR-
>tr|A0A0D0YUU5|A0A0D0YUU5_9LACO CRISPR-associated endonuclease Cas9 OS=Lactobacillus wasatchensis GN=cas3 PE=3 SV=1
-RHGAMYDQTLYKASGGKQLIRKKDNLPTEIYGGYTGSTDAFMSIIRM--KKK-DK---LYYKVIGVPTRVAHEVLS--DKFIETRITDWFE-LVIAKVM
YGQVIDDG-GQPFMLGSSTLPYNVRELYLAKDLVKVINKGS--TS---KSSYLDVYDELVK-LNKYF---PMYD-FRQKITDARDKFEKLQQIGQVTIID
RILIGLHTNAGVNLKDLGIATPFGFMQQISLTSTAKIIYQSSTGLFEKSKALD-
>tr|A0A0R1F6R4|A0A0R1F6R4_9LACO CRISPR-associated protein, Csn1 family OS=Lactobacillus coryniformis subsp. coryniformis KCTC 3167 = DSM 20001 GN=FD22_GL002102
-KSGALYNQTLYKASGTKQLIRKKDNMPTELYGGYTGSTSAFMSIVRL--WKK-DK---PYYKVVGIPTRMAAKLA----DYLTKTTVERFE-LVVPKVG
FNQLVIDG-GQPFMLGSATYQYNARELFISKEAVKALNKQL--ST---HVDLVQVFDEILV-VNRWF---PLYD-FREKLSHGRDRFMKL-SDTQIDVLN
RILIGFHANAARNLKILGLGTDLGFMTQIRLTEKAILVHQSPSGLFERKVALR-
>tr|A0A0R1ZCI7|A0A0R1ZCI7_9LACO CRISPR-associated protein, Csn1 family OS=Lactobacillus kefiri DSM 20587 = JCM 5818 GN=FC95_GL001315 PE=4 SV=1
-LNKEMFKQKLFPAT--SKLIQIKKDKPVDIYGGYSNNTDAYLTVVKL--KGS-KE---DKYKIVGVPMRALDNLKAEKEKALESKVVTNFD-IVLGRLF
YRQMVIDG-SEKSLIASSVYQYNAKQLVLSDQAIRTISDQE-----ELSSQYDKVYDEIVQ-VEKLL---PIFQ-FQERLNNGKSLFVNLEQVGKKHIIN
SILGGIHANADRDIDLFGIK-NLGQFSSINLSSDAIICYQSPTGLFERRVVLK-
>tr|S4NUM0|S4NUM0_9LACO CRISPR-associated endonuclease Cas9 OS=Lactobacillus otakiensis DSM 19908 = JCM 15040 GN=cas9 PE=3 SV=1
-LRGAMFNQTIYPAS--KKLIPMKADKPVDVYGGYSGSTDAYMAIVRI--HDK-KG---DKYKVVGVPMRALNRLNAKNVEVLTTQTVEDFE-VVLGKVM
YRQLVIDG-DKKFMLGSSTYQYNAKQLVLSDESIKTLASEG-----QESAAYDKVYDEILD-VNKYF---ALYD-FRQKLSLGKDKFVGLISSGKREILN
EILNGLHANATLTLSDIGFSTPFGKMQQIGLSSNTSIEYESFTGLFKRTIFLK-
>tr|A0A0R2K0E7|A0A0R2K0E7_9LACO CRISPR-associated protein, Csn1 family OS=Lactobacillus parabuchneri GN=IV42_GL002418 PE=4 SV=1
-LRGAMFNQTIYPAD--KKLIPTKADKAVDVYGGYSGSNDAYMVIVRI--HDK-KG---DKYKVVGVPMRALDRLNAKNVDVLTSRQVTDFE-IIVGKLM
YRQLVIDG-QEKSLIASSVYQYNAKQLVLSDDSIKTISNAE-----ILSTRYDQVYDEILQ-CKQFL---PIFQ-FQERLEAGQPQFSQLVRSGKKSIIN
SILRGIHANADRDLDLFGIK-NLGQFSSINLSPNTIICYQSPTGLFERRIILR-
>tr|A0A0R1S2S1|A0A0R1S2S1_9LACO CRISPR-associated protein, Csn1 family OS=Lactobacillus diolivorans DSM 14421 GN=FC85_GL001808 PE=4 SV=1
-RRDAMFNQTIYPAK--RKLIAIKHGKPVDVYGGYSGSVDAYMAIVRI--HDK-KG---DKYKVVGVPMRALEILNTHD-QILVTKKVEDFE-IVLGKVM
YRQLVIDG-DKKFMVGSSTYLYNARQLVLSDSSLDTLASKG-----ADSKRLVAVYDEIVE-VDKYF---PLYD-FRSGLHKGRDKYLLLVHSGKREILN
EILNGLHANATLGLKDLKISTPFGKMQGIPLSSNTIICYQSPTGLFEHRVSLK-
>tr|A0A0R1SDU2|A0A0R1SDU2_9LACO CRISPR-associated protein, Csn1 family OS=Lactobacillus parakefiri DSM 10551 GN=FD08_GL001962 PE=4 SV=1
-LRGAMFNQTIYPAD--KKLIPTKADKAVDVYGGYSGSNDAYMAIVRI--HDK-KG---DKYKVVGVPMRALDRLNAKNVDVLTSQTVEDFE-VVLGKVM
YRQLVIDG-DKKFMLGSSTYQYNAKQLVLSDESVKTLASKG-----QESAAYDNVYDEILD-VDRYF---ALYD-YRTNLHEGEQKFIGLVANGKRETIS
DILNGLHANATMNLKVLGISSPFGMFQSINLNPETIILCQSPTGLFERRIILR-
>tr|A0A0R1JG51|A0A0R1JG51_LACBU CRISPR-associated protein, Csn1 family OS=Lactobacillus buchneri DSM 20057 GN=FC79_GL001583 PE=4 SV=1
-LRGAMFNQTVYPAS--RKLIPIKADRPINVYGGYSGSADAYMAIVRI--HNK-KG---DKYRVVGVPMRARDRLDAKKVDVLTTQVVEDFE-IVLGKVM
YRQLMIDG-DKKFMLGSSTYQYNAKQLVLSDQSVKTLASKG-----QESMDYNNVYTEILD-VNQYF---SLYD-FRHKLNLGFSKFISFASSGKREILE
EVLNGLHANPTFNLKDIGITTPFGQLQQILLSDEAKIRYQSPTGLFERTVSLK-
>tr|A0A0R1K630|A0A0R1K630_9LACO Uncharacterized protein OS=Lactobacillus namurensis DSM 19117 GN=FD30_GL002021 PE=4 SV=1
-NHGALFNQTIYPAS--KKLIPQKTEKPIELYGGHSSEQAGYMAIIRL--LGK-RP----GYKVMRVPVRYVSQLQ---QKIFV-NKVKPFE-VVVPHVC
LNQPVEDM-WHRFALRTNGYYQNQQQLILSLVAQRTLAGYK------KDDELMAVYHEICK-VKYYF---PLYK-FQSRLFAAEELLQKILNLGKRELLL
RLLGGLHANATRDLKDIGCTGQFGQLQVIKLTEQAVLIHESPTGLFHRRVRLN-
>tr|A0A0R1MNC7|A0A0R1MNC7_9LACO Uncharacterized protein OS=Lactobacillus zymae DSM 19395 GN=FD38_GL000773 PE=4 SV=1
-NHGALFNQTIHPAK--RKLIPRKTTQSTELYGGYSGETTGYLAIART--VTK-NK---ISYQVLRVPTRLVGRLQ---SDWFA-GKQQPFE-IVLRHVF
KNQTVIDD-SHRFGLRSDTYYCNQQQLVLSLEQQRMIIDQKN-----NTNKLMVVYEAVCD-VAKYF---PLYR-FKESLLEAGPKLAELLKLGQRSVLL
QTMQGLHANPETDLSIIGCPKYFGKLQVIKLTENAVLIHESPTGLFQRRVRLS-
>tr|C2D302|C2D302_LACBR CRISPR-associated endonuclease Cas9 OS=Lactobacillus brevis subsp. gravesensis ATCC 27305 GN=cas9 PE=3 SV=1
-RQDALFNQTIYPAS--RKLIPIKNSKPVDVYGGYSGNIDAYMAIVRV--HGK-KE---DNYKVVGIPMRAVTKLKAEKEEVLKTETVDEFD-VLLGKVY
YRQLIVDG-NKKFMLGSSSYQYNAKQLVLSDKAMQVLSKNG-----DENQNLIDVYDEILE-VDQYF---ELYD-YRESLHKGRGIFVNLTSYGKYETID
AILNGLHANATMNLRYLGISSPFGKMQALTIDPDSIICYQSPTGLFERQIKLS-
>tr|C0WRP7|C0WRP7_LACBU CRISPR-associated endonuclease Cas9 OS=Lactobacillus buchneri ATCC 11577 GN=cas9 PE=3 SV=1
-RQDALFNQTIYPAS--RKLIPIKNNKPVDVYGGYSGNVDAYMAIVRI--HGK-KE---DKYKVVGVPMRAVADLKAESKEVLKTEMMDDFD-VLLGKVY
YRQLIVDG-NKKFMLGSSTYQYNAKQLVLSDKAMQVLSKDD-----DENQNLIDVYDEILE-VDQYF---ELYD-FRQKLHDGRKKFIELISYGKRATII
SILNGLHANATMNLKYLGISSPFGMLQVIILSPASRICYQSPTGLFERKVKLS-
>tr|E7FPD8|E7FPD8_9LACO CRISPR-associated endonuclease Cas9 OS=Lactobacillus ruminis ATCC 25644 GN=cas9 PE=3 SV=1
-RTGAMFNETRYPAPKPDSLISVKDYKNTDIYGGYSGKNDAYMVIVDM--G---K-----QYMVVGVPVRYTEKLDLRIKKVLSKGNVKRFD-IVLDRVL
YGQLIEDG-NELFTLGSSKYKRNFRQLFLDKQCIEILDSSA-----PTDEELIWVYDQILD-VDKYF---ELYD-QRETLRKGRAAFCSLDDVTKKKILN
EILVALHANESENCEKIGK-KVFGRLQVIKLSKEAKLIYQSPTGLFERVVYLK-
>tr|A0A0R1SG79|A0A0R1SG79_9LACO CRISPR associated protein OS=Lactobacillus diolivorans DSM 14421 GN=FC85_GL001324 PE=4 SV=1
-RQGAMFNQTIYPAS--RQLIPVKKNRATKLYGGYSGNVDAYLAIVRL--GGP-KS---DQYRVVGIPTRMVGRLQAMKQKILQEETTEPFA-VILDKVY
YRQLIIDG-QQKFMLGSSTYQFNAKQLVLSSRARQILSGEE-----NGSQDLIDVYDEILT-IDRYF---ELYD-FRQSLHDGRKQFISLIEHGKYETLS
QILNGLHANTMMNLRYLGISSPFGKFQSIKLSKDAVLVYQSPSGLFERRVRLR-
>tr|A0A0R2I8Q5|A0A0R2I8Q5_9LACO HNH endonuclease family protein OS=Pediococcus inopinatus GN=IV83_GL000804 PE=4 SV=1
-RRGALYNQTVYKASGSKKLIPIKSDKPTEIYGGYTGRTLAYMTIVKV--TKG-KK---ISYKVVGVPTAVLAKMAVRQGGVLKTETVDKFD-IIVPKVK
YQQLVNDN-GQLFMIGSDTLPYNAEQLVLSKESVQTINNPGKDEGSSENKKLDNVYDEIVL-MNKYF---PLYD-FRNSITNGKNKFLKLINVGKREVIN
RILQGLHANASVDLSNLGIKSPFGFLQKLSLSGEAQLIHQSATGLFEHRVQLN-
>tr|A0A081BKX9|A0A081BKX9_9LACO CRISPR-associated endonuclease Cas9 OS=Lactobacillus oryzae GN=cas9 PE=3 SV=1
-RHGALFDQTLYKASGSKKLIPAKDNRPTELYGGYSGQTSAFMAIVKV--TKG-KK---TKYLVVGVPTAAISQLQMDVKNILS-SKNDDFE-VIVPKVR
YRQLILDN-NQLFTLGSDTYKYNARQLVLSNEVLAVINRDKFI-DKAENQALNDAFDEIVV-MDKHF---DLYD-FREKVKAGKQRFEELEGITKRTVLK
RILQGLHANATTDLKVLDGKFYN-------------------------------
>tr|A0A0R1UKG9|A0A0R1UKG9_9LACO Uncharacterized protein OS=Lactobacillus hammesii DSM 16381 GN=FD28_GL000928 PE=4 SV=1
-DHGALFNQTIYKAKGKMKLLPTKSNRPTEIYGGHSSQAIAYLAIVRV--NG--KE---PSYRVMGVPIRILDQLKAKKQQFFTGKIVSDFD-VVIPHIP
LLQPVIDE-SHRFALGTNTYYRNLQQLILTLADQKVLISKEG----DEEKKLVEVYSHICQ-VMKFF---PLYD-FRELLVDSRSHFEQLEIAGKRGILQ
QIMVGLHANATPDLKELGVKTPFGKLQVIKLTENAKLIYESPTGLFKREVKIT-
>tr|A0A0F3FWK9|A0A0F3FWK9_9LACO CRISPR-associated endonuclease Cas9 OS=Pediococcus damnosus LMG 28219 GN=cas9 PE=3 SV=1
-KRGALYNQTIYKAKGSKKLIRIKDDKETKIYGGYSGKSLAYMTIVQI--TKK-NK---VSYRVIGIPTLALARLNLENDKIIKIETTDDFK-IVVSKVR
FQQLIDDA-GQFFMLASDTYKNNAQQLVISNNALKAINNTNTDCPRLDNLRLDSAFDEIVK-MDKYF---SAYD-FREKIRNSNLIFYQLTELGKRTVLT
RILQGLHANATTDMSIFKIKTPFGQLRQISLSENAQLIYQSPTGLFERRVQLN-
>tr|A0A0R2IP06|A0A0R2IP06_9LACO HNH endonuclease family protein OS=Pediococcus parvulus GN=IV85_GL001523 PE=4 SV=1
-RRGALYNQTVYKASGSKKLIPIKANKPTEIYGGYTGKTLAYMAIVKV--IKG-KK---IAYKVVGVPTSALVQLAIEHGDVLKSETVSKFE-IVIPRVK
YQQLVEDD-DKLFMIGSDTYPYNAQQLVLSEGALKVINNVYKGENSQESYKLDDVYDEIII-MKKYF---PLYD-FREKVAEGKSTFENLTKIGKKEVIN
RMLQGLHANATMDLKILGIKSPFGFMQQIALSENAQLIYQSPTDLFERRVQLN-
>tr|A0A0R1RHH9|A0A0R1RHH9_9LACO Uncharacterized protein OS=Lactobacillus rossiae DSM 15814 GN=FD35_GL002365 PE=4 SV=1
-NNAQMFKQTVFKAR--KTLIPVKNGLSTDVYGGHSQQAISYLCIVWV--GQK-K-----KYRVLGISTAHAGILNFEKNEIVSNADRNDFK-IVAPKVL
FEQVVEDD-NMKFGLGSASDYRNVQQLFLSRKNQLLLANMMD----IHDQDLVHLFDEIVG-MNAHF---PIFD-YRSSLTQSRDKFLKLDLITKQEVIR
RILDGLHANANRDLKIIGSKGDFGRLGTIYLSKDAKLIYTSPTCLFTRTVPLS-
>tr|F6ITQ2|F6ITQ2_LACPE CRISPR-associated endonuclease Cas9 OS=Lactobacillus pentosus MP-10 GN=cas9 PE=3 SV=1
-NYGAMFDQTIFKAT---RLIQKKKGFATETYGGYTGRTLAYLAIVKV--VTN-KD---TQYQVVGIPTTMVTQIQLEASKAIGNKKLQSYE-VLLPKVR
FEQVVRDE-IHRFALGTDTYYHNIQELYLPLTIQRAFLGKRDTD--QTEQNLLTVFETTLA-VNRYF---PLYE-FKQILNSAQEKFAALLVTGKDGVLN
NLFIGLHANASLDLKILGMKIGFGKLQVLKLTDQAEIIYQSPTGLFERKVALK-
>tr|I9L4B5|I9L4B5_LACPE CRISPR-associated endonuclease Cas9 OS=Lactobacillus pentosus KCA1 GN=cas9 PE=3 SV=1
-NYGAMFKQTLFKAS--KTLVPKKNHMETSVYGGYSNQETAYLAIVRI--PFK-SG---FKFIVVGIPTRMVAKIKYQSLKVIEQTVISDYE-VVLPKVY
LDQVVRDQ-MYRFSLGSDKEYHNVQELYLPLSIQQAFVGHYESD--QRSNDLVKVYDAALK-LQRYF---PLHL-FDQVASQAHQSFEGLKQLGKKEVLN
SLFVGLHANATRNLSVLGMSKDFGRIKSITLTDQAEIIYQSPTGLFERKVALK-
>tr|A0A0R2KUQ3|A0A0R2KUQ3_9LACO Crispr-associated protein, csn1 family OS=Pediococcus stilesii GN=IV81_GL000856 PE=4 SV=1
-RHGAMFNQTIYPAS--KKLIPIKKGKDTAIYGGYSGNTDAYMAIVAV--EDK-KG---EKFKVVGVPTRAVSRLELAADDVLKEEVTTPFR-ILVGKVG
YRQLIQDG-QVKMMLGSSAYKYNAKQLVLSEKSLKVIKNNK-----DENQDLIDVYDEILG-VNRAF---NLYD-FRKKLNDNRVKFVELVQMGKRAVLT
QILNGLHANAALDLKALGISTPFGKMQSIPLSMDASLVYQSPTGLFERKLNLS-
>tr|A0A0R2IVX3|A0A0R2IVX3_9LACO Csn1 family CRISPR-associated protein OS=Pediococcus parvulus GN=IV85_GL002431 PE=4 SV=1
-KHGALFNQTIYSAK--KTMIPIKNDRPTKLYGGYSGNEDAYMSIIRL--SDKKK-----TYKVVGISMRDASKLKYENNEVIE--TKADFE-IVIPKVN
YHQRMQDG-TKQFRIGSSKYVHNTKQLVLSEKTLKAIRNNK------AEKDLINAFDEILT-VNDSF---SIFD-FRKKLNESRDKFVSLVIKGKRETLK
QILIALHANGTSDIPQLGL-KSFGKMVKLTLSENTALIHQSPSGLFEHKIKLS-
>tr|A0A0R2EK58|A0A0R2EK58_PEDAC Csn1 family CRISPR-associated protein OS=Pediococcus acidilactici GN=IV78_GL001470 PE=4 SV=1
-RRAELFNQTVYPKN--GKLIPIKEDRPTDLYGGYSGNTDAYLAIVAL--EDKKKG---KYFKVVGIPTRVAAKLELKQQKVIA-IKKTEFE-IVLDKVH
YRQLVQDG-PVKMMLGSSTYKYNAKQLVLSEKALQVIADDR-----QKDDNLIAVYDEILS-VNQSF---DLYD-FRKKLNDNRDQFIDLVAHGKREMIL
EILKGLHANAAFNLKPIGFSTAFGQLQVIILSKNAILIHQSPSGLFERKIKLS-
>tr|I7L6U4|I7L6U4_9LACO CRISPR-associated endonuclease Cas9 OS=Lactobacillus hominis DSM 23910 = CRBIP 24.179 GN=cas9 PE=3 SV=1
-HDQEMFKMTVYPRLKSRNLIPKKKDMPTEIYGGYTNNSDAYMIIARI--NKK-KG---PEYRVFGVPMRELVNLRAEK-QVLENKTISSFE-IVKAKVP
YKQVILDG-DKKFMLASSTYVQNAKQLTLSQYSMQAITDNC-----EEEKALVEAYDEILT-IDKYL---PLFD-FREKLHAGREKFVDL------ETIL
QVLNGLHDNAVMKIKSLGLSTPLGF-MQVSLSENAKLIYQSPTGLFEKRLKIS-
>tr|F4AF10|F4AF10_LACJH CRISPR-associated endonuclease Cas9 OS=Lactobacillus johnsonii DPC 6026 GN=cas9 PE=3 SV=1
-RDQEMFKMTVYPRFAPRNLIPKKMGMSPDIYGGYTNNSDAYMVIVRI--DKK-KG---TEYKILGIPTRELVNLKAEK-EILTDKKITSFE-IVKSKIP
YKQVIQDG-DKKFMLGSSTYVYNAKQLTLSTESMKAITNNF-----DENDALIKAYDEILD-VDKYL---PLFD-FREKLHSGREKFIKL------DTIL
KVLEGLHDNAVMKIPTIGLSTPLGF-MQVILSENAKLIYQSPTGLFKKSVKIS-
>tr|K0MXA7|K0MXA7_LACCA CRISPR-associated endonuclease Cas9 OS=Lactobacillus casei W56 GN=cas9 PE=3 SV=1
-EKADLFKQTVYGAKGKKQLISKKKGYPVDIYGGYTQETGSYLSVVRL--TKK-A-----MYAVVKVSTRDAAKLAAKSIDIIDKITHELFE-VVLPRVG
QKTLFKNS--NLFLVNSDTYMHNYQELWMPREYQKMWKDISS----QTEDQLDQIFGFIVS-VNSYF---NLYD-FRKKLNDAADKFATLDMQGKIATIG
QLLIGLQANAARDLRNLDIKTPLGLLQIISLDSDTSVVYQSPTGLLEREVHLS-
>tr|S2PX48|S2PX48_LACPA Uncharacterized protein (Fragment) OS=Lactobacillus paracasei subsp. paracasei Lpp123 GN=Lpp123_03279 PE=3 SV=1
-ETASLFKQTLYAAKGSRQLIPKKKGYLVDIYGGYTQETGSYLSVVRL--TKK-A-----MYAVVKVSTRDAAKLAAKSIKIIDKTTHQLFE-IVLPRVG
QKTLFKNS--NQFLVNSDTYMHNYQELWMPREYQRMWKDILS----QLEGQLDQIFKFIVS-VNSYF---NLYD-FRKKIADATDKFAKLNARGKIATIG
QLLIGLQANAMRDLRNLDIKTPFGLLQIITLDLDTSIIYQSPTGLFEREVPLT-
>tr|A0A0H0YP06|A0A0H0YP06_LACCA CRISPR-associated endonuclease Cas9 OS=Lactobacillus casei GN=cas9 PE=3 SV=1
-ETAGLFKQTVYAAKGSRQLIPKKKGYSTGIYGGYTQETGSYNALVRL--TKA-GK---VVYRVFKISTQNAAEIAARSLQILEKNTVDLFD-VVIPRLG
KEALFHNS--GLFLVNSDTYYHNYQELWLSRENQKILKKLFT----EMDRDALHLFETIAK-VEQFF---KLYD-FRTKISSAFDAFEKL--EGKVETLK
QLLIGLHANPVRDLKNLGIKTPFGFLQAIHLDDDTEIIQQSPAGLFKRRVRLA-
>tr|A0A0M2FYH7|A0A0M2FYH7_LACRH CRISPR-associated endonuclease Cas9 OS=Lactobacillus rhamnosus GN=cas9 PE=3 SV=1
-ETADLFKQTIYAAKGSKQLIPKKQGYPTQVYGGYTRENTAYLAVVKT--VEK-KA---DVYRVVRIATSQVAALKARAQKFLTKKAITPFD-IVIPRVP
REQLFHNK--GFFMVNSDTLMHNYQELWMSRSDQQILSKLVS----VENGQVGRLFENIVE-INKYF---PLYD-FRKKLDQSKDIFSKLTTSGKRETIQ
NILTGAGTGAKNDLKNLGIKTPFGFLQVIVLDDDTTLIYQSPTGMLNRIVRLS-
>tr|C5F8S2|C5F8S2_LACPA CRISPR-associated endonuclease Cas9 OS=Lactobacillus paracasei subsp. paracasei 8700:2 GN=cas9 PE=3 SV=1
-ETADLFKQTVYGARGSKQLIPKKKGYPVDIYGGYFRENTAYLAVVKV--TKK-TE---TIFKVVKIATSQVAALNARSRELLKKITDTPFE-VVLPRVP
REQLFYNA--GFFMVNSDTMFHNFQEIWVSRSDQKILQQIRA----NVDQDLDNLFHNLAD-IVKYF---DLYS-FKEKISQSQNTFNDLQSVGKITVIN
ELLKGAQANGMTSLKVLKISTPFGFTQDV-LTKDSSIIYQSPTGLFERSVRLT-
>tr|C7TEQ6|C7TEQ6_LACRG CRISPR-associated protein OS=Lactobacillus rhamnosus (strain ATCC 53103 / GG) GN=LRHM_2119 PE=3 SV=1
-ETADLFKQTIYAAKGSKQLIPKKQGYPTQVYGGYTQESGSYNALVRV--AEA-DT---TAYQVIKISAQNASKIAANLKEIVVKPSANSFK-IVIPRFG
MGTLFQNA--GLFMVNSDTYYRNYQELWLSRENQKLLKKLFI----QMNHDALQVYKAIID-VEKFF---KLYD-FRAKLSDAIERFEKLNKIGKTETLR
QILIGLQANGTRNVKNLGIKTDLGLLQVIKLDKDTQIVYQSPSGLFKRRIPLA-
>tr|D6S374|D6S374_9LACO CRISPR-associated endonuclease Cas9 OS=Lactobacillus jensenii JV-V16 GN=cas9 PE=3 SV=1
-RNNNMFKQTLFPIIKTKSLIPKKLDRPTDIYGGYSNNNDAYLALVKV--DKK-RG---SEYRVVGIPMRAAAMLK----KVIEKRGIEGFR-VLVGKMP
FKQAVLDG-NKKFMLTGTVDTPNLKQLVLSQQNMKYILDYIDVDCRNPDKCLLEVFDEIIE-VDKYF---ELFD-FREKLRNSRNKFIKL------DTIL
AILKGLQAKSTRTIKELNIS-DFGRIIT-SISPEAQLIYQSPTGLFERRVKVK-
>tr|A0A0R1S4R8|A0A0R1S4R8_9LACO Uncharacterized protein OS=Lactobacillus psittaci DSM 15354 GN=FC23_GL000761 PE=4 SV=1
-NSNNVFKQTVFPIIKSRSLIPKKLDRPTDIYGGYSNNNDAYLALVKV--DKK-KG---SEYRVVGIPMRAAAMLK----KVIEKRGIEGFR-VLVGKMP
FKQAVLDG-DKKFMLTGTNDMPNLKQLVLSQQNMKYILDYIDIDCRDGNKCLLEVFDEIIQ-VDKHF---ELFD-FREKLRNSRVNFINL------EALL
AILNGLHANSMRTIKELKIS-DLGRIQS-VISPEAQLIYQSPTGLFERRVKVK-
>tr|A0A0R1Z3F5|A0A0R1Z3F5_9LACO CRISPR-associated protein, Csn1 family OS=Lactobacillus jensenii DSM 20557 GN=FC45_GL000799 PE=4 SV=1
-ETSSLFNQTLYAH-VKNSLIPKKKGLPTEIYGGYSGNKDSFFVLVKI--VKK-RT---NLYRIVGIPTRELAKLN----KIVE--ETESFK-ILIKRLL
YGTLIVDN-GQKFRIGSFKEKHNVQQLVLQLKSMKYIKFYIGGQNYDRDKCLLYVFDDIMN-VNKRF---TLFD-YEKDGDSLREKFNCL------SILS
DLLKAFHANSDRSITKLKIT-NLGRHQAITLTTNAQIIYQSPTGLFERRIKIK-
>tr|A0A0D4CLL6|A0A0D4CLL6_9LACO CRISPR-associated endonuclease Cas9 OS=Lactobacillus mucosae LM1 GN=cas9 PE=3 SV=1
-QHGQLYGATILPVA-ISAPIGIKDDKPVDIYGAYTNEVAAYMAIVRV--NGKKP-----KYKVVSVPVRMLQRLKAEQKDVLLEAVVKDFD-VLVPCVR
YNQLVIDG-DTKFTLGSATYQHNAKQLVLCNHSLETLANNFEYV--EADERMIMLYDDILD-VNHYF---TLYD-FREKLNAGRDKYLKLTAIGKSEAII
NILRGLHANAAINLKCLGVSTPFGQLQSIELSENAKLVYQSPTGLFSREVLLK-
>tr|D0DRL9|D0DRL9_LACFE CRISPR-associated endonuclease Cas9 OS=Lactobacillus fermentum 28-3-CHN GN=cas9 PE=3 SV=1
-RSDQLYGATIVTAK-LTSPIEIKKKRPVDLYGAYTNGTSAFMTIIKF--TGNKP-----KYKVIGVPTTSAVGLKVGKPRIIKPKVKKDFE-IVVPHVS
YSQLIVDD-DCKFTLASDTYQHPATQLVLSKESMEIIADDFKFV--TADEQLVRVFDEIVN-MNHYF---TIFD-NRQKVTKARDKFVSLTQVGKTEVIT
NLLMGLHANSAQDLKVLGLS-TFGFFQSLNLSEDAMIVYQSPTGLFERRICLK-
>tr|A0A0N0CQ86|A0A0N0CQ86_9LACO CRISPR-associated endonuclease Cas9 OS=Lactobacillus apinorum GN=csn1 PE=3 SV=1
-KSGQLFKQTIYSAK-LKSAIPVKSNLEPSIYGYRSGNVDHHMVIVKI--KKG-TK---YSFKVIGISARAIQELEAKKIEVVSMKSVESFR-IILDNIM
YGQLIVDG-NDKFTLGSADYRKNSRQLVLCTNSLKILKDEDMN---QRSKLMVQVYDEIIK-MKNKY---SLFI--TEKLLEKRDIFCGL---EQKIVIW
KIIIDLHNGP-FKIQELGINNKMGTFQTIILTENAIVIYQSPSGLFERKVRLK-
>tr|A0A0P7LUX3|A0A0P7LUX3_9LACO CRISPR-associated protein, Csn1 family OS=Lactobacillus kunkeei GN=RZ76_08710 PE=4 SV=1
-KNGQLSDQTVYSAR-VNSPIPVKKDSNPELYGFRTGNVDHHMVIVKY--LNK-DK---YDYKIIGIPLRFVQVLKSNDNKIVQ--KSTDFR-VILDNVM
YGQLIQDG-GQKFTLGSSTYKYNAKQLVINMDDIRILVDNRFN---DASGEFIKIYNEILK-INARF---DLFD-FREKLNNGKEYFENL---EKNQVLL
KMLSGLHCGSANPIKELGLTTPLGKLQIIVLSEDAIVIYQSPSGLFERKIRLK-
>tr|A0A0N0CU60|A0A0N0CU60_9LACO CRISPR-associated endonuclease Cas9 OS=Lactobacillus kunkeei GN=csn1 PE=3 SV=1
-KNGQLSDQTVYSAK-VKAPIPVKKDFNPELYGFRTGNVDHHMVIVKY--PKK-DS---YDYKVVGIPLRFVQKLKTKDNQIVQ--KKQDFI-VVVDNVM
YGQLIQDG-GQKFTLGSSTYRYNAKQLVIDNGYLKLIADERKN---EKSNQYITLYNEILK-VNGRF---DVFD-FRKKLNNGVDKFIKL---DKRIIIM
KILSGLHCGPSIPLKELGLTTPLGQLQSISLSENTIIIYQSPSGLFERKVRLG-
>tr|A0A0N0UTU1|A0A0N0UTU1_9LACO CRISPR-associated endonuclease Cas9 OS=Lactobacillus kunkeei GN=csn1 PE=3 SV=1
-KDDKLSDQTVYSAK-VASPIPVKKDSNPELYGFRTGNVDHHMVIVKY--PKK-DS---FVYKVVGIPIRFMQELRSKNQQIVQ--KKFDFR-VVVDNVM
YGQLIQDG-GQKFTLGSSTYRYNAKQLVLDMDSLRILSDEKRN---EKNSEFINIYQQVLN-VNEKF---DVFD-TRDKLTKGLDKFLNI---DKEIVLL
KILSGLHCNAARKINEIGINTSFGELQTIVLSENSYIIYQSPSGLFERKVRLK-
>tr|A0A0C3A2P0|A0A0C3A2P0_9LACO CRISPR-associated endonuclease Cas9 OS=Lactobacillus kunkeei GN=cas9 PE=3 SV=1
-KNGQLSDQTVYSAK-VKAPIPVKKDSNPELYGFRTGNVDHHMVIVKY--PKK-DS---YDYKVVGIPLRFVQKLKTKDNQIVQ--KKQDFI-VVVDNVM
YGQLIQDG-GEKYTLGSSTYKYNAKQLVINMDKTRILEDNRLN---EVSEKLVNIYNDIMK-VNSRF---DLFD-FREKLNDGLNKFKNI---QKEETLL
KILSGLHCGSANPIKELGLTTPLGKLQLIVLSEEAVVIYQSPSGLFENKVRLK-
>tr|A0A089Y508|A0A089Y508_9LACO CRISPR-associated endonuclease Cas9 OS=Lactobacillus sp. wkB8 GN=cas9 PE=3 SV=1
-ENSNMFNMTIYPRGKTRKLIPKGKDLDPAIYGGYSGNTDAYMVIVKI--EKT-KE---TLYKVVGVPMRALASLKAQK-KVLEKAGIKGFT-VVKDHVH
FKQVVIDG-DSKFMLYSAQYRANAKQLTLSQETMKVVTDNTDMDQ-DKDQLLLNAYDEILE-VDQYL---PLFD-FRQGLHDGRAKFAAL------YTLK
NILNGLHDNLVTNLKNIGIKTPFGL-MQITLSPNAKLVFQSPTGLFEKRVKLT-
>tr|A0A0F4LLE0|A0A0F4LLE0_9LACO CRISPR-associated protein cas9 OS=Lactobacillus apis GN=cas9 PE=4 SV=1
-TDEAMTKATIYPRATRTSLVPKKKG-DPEIYGGFSNSKNSFMVIVKI--KTAKED----TYKAIPIA--MRY----RDT-LE-TRGYRGFD-IIVNHLN
FNQEMV---YGNFILSKATYMYNGNQIVLSPDAMRIL---------DEDSSLVKVYDEILEQVDKYL---PLFNMN-QKLHDARKVFEKLDVRKKRSTLS
SILRGLHCNSSS---ELGIGTGFGFFQKIPLTSDTLIVFKSITGLRRRKVSLS-
>tr|A0A0F4LG72|A0A0F4LG72_9LACO CRISPR-associated endonuclease Cas9 OS=Lactobacillus melliventris GN=cas9 PE=3 SV=1
-ESSSMFNMTIYPRGKTRKLIPKGNGLDPKIYGGYSGNTDAYMVIVKI--EKA-KE---SIYKVIGIPMRALAGLKAKN-KVVEKRGVEGFR-VVKDHVP
FKQVVLDG-DKKFMLYSAKYETNAKQLTLSQETMRIVTDNL-----DQDKLLVKAYDEILQ-VDQYL---PLFD-FRNSLHLGRAKFLDL------ITLS
NILNGLHDNLVVNLKNIGIKTPFGL-MQITLSSNAILIFQSPTGLFEKRVRIA-
>tr|A0A0F4LMR6|A0A0F4LMR6_9LACO CRISPR-associated endonuclease Cas9 OS=Lactobacillus kimbladii GN=cas9 PE=3 SV=1
-ESSSMFKMTIFPRGKTRKLIPKGNGLDPKIYGGYSGNTDAYMVIVKI--DKA-KE---SIYKVIGVPMRALTRLNAKK-QVLEKRGVKGFR-VIKDHVP
FKQVVLDG-DKKFMLYSAQYKTNAKQLALSQETMRIVTDNL-----DQDKLLVKAYDEILQ-VDCYL---SLFD-FRNGLHLGRNKFIDL------ITLS
NILNGLHDNMVLNLKNIGIGTPLGQ-MQITLSPEAVLIFQSPTGLFEKRVKIA-
>tr|A0A0F4LIJ0|A0A0F4LIJ0_9LACO CRISPR-associated endonuclease Cas9 OS=Lactobacillus kullabergensis GN=cas9 PE=3 SV=1
-ENSGLFDVTIYPRGKTRKLIPKSNGLDPKIYGGYSGNTDAYMVIVKI--DKG-KE---SIYKVIGVPMRALASLNAKK-QVLEKRSVKGFR-IIKDHVP
FKQVVLDG-DKKFMLNSSTYEINAKQLTLTPETMRIVTDNL-----DQDQLLVKAYDEILQ-VDQYL---PLFD-FRNSLHLGRAKFLDL------ITLT
NILNGLHDNLVTDLKNIGIKTPLGK-LQIVLSSEAILIFQSPTGLFEKRVRIA-
>tr|A0A0R2DLB6|A0A0R2DLB6_9LACO CRISPR-associated protein, Csn1 family OS=Lactobacillus floricola DSM 23037 = JCM 16512 GN=FC86_GL000147 PE=4 SV=1
-KQGQFYNETIYPAK-TAKMIPLKDNKPSEVYGGYSSSNVSKIALIK----EK-NT---DNYQFIGIPIRSIAKLKAKANRVIKTKKQKEFE-VILDNVK
YNQVVVDQ-GEKYYLGSPYYKKNAKQLVISPESVKILADKA-A---EAHNKLMTVYQEIVD-LNKHF---ALYD-VRKKLNDGLIKFSQLSIKTKYAVIM
RILSGIKNQTS-EVPELGLKSPLNKMQTIKISPEAKIYYSSPTGIFSHFKQVK-
>tr|R7FJU9|R7FJU9_9CLOT CRISPR-associated protein cas9/csn1 subtype II/nmemi OS=Clostridium sp. CAG:288 GN=BN588_00731 PE=4 SV=1
-SAGDLYKETIFEKADSVNLIPCHTK-DTKKYGGYSQINQSYILAVEY--TSGKKT----VKKLLRVPTMYLNLYGNNEEKLIVDEKAKDIK-ILR-KIY
INQKIKYN-GCYYRIFTKG-KNNAYQNYIDNNIVLYLNKSLLSDD-ISKEKNKIIFDTIKEKRYDEC---SYFEKARE---MKFEIFNNLSLKEQISTLI
NMLKLLSCSTESNINEFKVEKRL--LFVDITKEEIYIVNESPSGLFKGKEELI-
>tr|A0A0L0THX9|A0A0L0THX9_9LACO Uncharacterized protein OS=Lactobacillus delbrueckii subsp. sunkii GN=LDS38_04275 PE=4 SV=1
--EG-----GLFNSTNPKKAVPRKKN-SPEVYGFYSGTVTSKIVLIKT--VKQTKDGKSNQYSLDKLTNLSKS----DEEKLVD-----------ERKVP
VEDGEGHQHTERILLSSDEEYHNFNGFTLSDNAMSFLQTFNNESDKDANDALNQIFDEILLKCKLEL---PLISQPFESLSSAKAIKAF-DLSKKLQDIE
SILLAVSDTSRLLSSVKGLKGTLGRFNRSHLMDDTVLVFRSATGLFERKIAFK-
>tr|S2KA46|S2KA46_LACDL CRISPR-associated endonuclease Cas9 OS=Lactobacillus delbrueckii subsp. lactis CRL581 GN=cas9 PE=3 SV=1
-KKSALFDQTVYPSPKRSGLIPRKKGMDTEIYGGYSGNKDAYFVLAEA--VKE-KG---HTLQIVGVPIRALNTLK----EIIKIKGIKDVK-ILMDKIP
CRQPVLEG-ESYYMLASSKYRYSLKQISLSQMSMKYILDYIDPNFNDEKECLLSVYDEILE-MDKYL---PLFD-FRKKLHDGRDAFIALKKPGKVDVIR
KVLKGLHANADINLAELGFGAALGA-LVIKISDDAVFIYQSPTGLFERRVKVS-
>tr|K0NQV3|K0NQV3_9LACO CRISPR-associated endonuclease Cas9 OS=Lactobacillus equicursoris 66c GN=cas9 PE=3 SV=1
-KKSALFDQTVYPSPTRSGLIPRKQGMDTEIYGGYSGNKDAYFVLAQV--VKS-KG---HTLQVVGVPIRALRALA----KIVKKKGISDVR-ILLDKIP
YRQPVLDG-SAFYMLGSSTYKYNLKQISLSQQSMKYILDYIDPNFNNEKECLLSVYDEILD-MDKYL---SLYD-FRKKLHVGRDKFIKL------EAIK
NVLRGFHANSDMKLSDLGLSTSLGF-MQIKLSDNAVFIYQSPTGLFERRVKVS-
>tr|A0A0D6ZH65|A0A0D6ZH65_LACDE CRISPR-associated endonuclease Cas9 OS=Lactobacillus delbrueckii subsp. bulgaricus GN=cas9 PE=3 SV=1
-KKSALFNQTVYPSPKRSGLIPRKRGMDPEIYGGYAHNQDSHFVLAKI--EKV-KG---YTLQIVGVPIRSLEIIN----DIIKKRGIKNVE-ILVNKLP
YRQPILEK-DVSYMLGSSAYKYNIKQITLSRQSMKYILDYIDPNFTNERECLLSVYDEILE-VDKYL---PLFD-FREKLHSARKEFVSL------SAIE
KILRGLHANSEMSLENLKIKPALGF-FQITLSNDAVLLYQSPTGLFERRVKVS-
>tr|A0A061CF22|A0A061CF22_LACDL CRISPR-associated endonuclease Cas9 OS=Lactobacillus delbrueckii subsp. lactis GN=csn1 PE=3 SV=1
-RKSALFDQTVYPSPKRSGLIPRKKGMDTEIYGGYSGNKDAYFVLAEA--VKE-KG---HTLQIVGVPIRALNTLK----EIIKKKGVNDVR-ILMDNIP
YRQPVLEG-GALYMLGSSTYKYSLKQITLSQESMKYILDYIDPSFNDEKKCLLSVYDEILD-MDKYL---PLFD-FRKKLHDGREKFVKL-----AEVVK
DILRGLHANSEMKPSDLGLT-ALGF-MQIKISDDAVFIYQSPTGLFERRVKVS-
>tr|E3CL85|E3CL85_STRDO Uncharacterized protein OS=Streptococcus downei F0415 GN=HMPREF9176_1172 PE=4 SV=1
------------------------KKLDVEKYGGYQGLVTSFTILIFETGKKGKSK-------IENIPIFDRNKFEENPKAYLKEK-YPNF--EDYVELP
KYSLLEFKKGYRRYLVSARELHPACQFRLPKRYWKFMYKMDKMIKELGVNVEKMY-EGLLEYCISFMKRNCLDKTFKDKKISYFSDARFSSICAVHIEFK
LLSALTTKGGST-TDFFSEKGDKFRYQGTGELANATLIRQSITGLYETRIDLG-
>tr|A0A0A0M6D4|A0A0A0M6D4_9LACT Uncharacterized protein OS=Oenococcus alcoholitolerans GN=Q757_04295 PE=4 SV=1
VHVGKLYNETVYKNPTKRKLVPYKGNKNTQYYGGFSSTTSAYSALIRV--NAKNS----HSNVVVKIPLAVANQIDKKITDYISSLNIKGFE-LVIDSIK
LGQLVKESDGSLFFLASSEYKHNAKELWLPINIYKIVGKNLTKM--PDQDNLIKIFDSITSEVEKRFRFYKN---DIVHLRSLRSEFLQLDLSKQQADLI
HILGNDAYRDPIKYFKSEKAKTLHTQDHIKLSDDAEFIFQSPTGLFTKTVSVS-
>tr|T0TRJ9|T0TRJ9_LACFE Uncharacterized protein OS=Lactobacillus fermentum MTCC 8711 GN=N219_11920 PE=4 SV=1
EETGKYFDASLYLN-KSKLVVPLKNKLQPEYYGAYTGITQGYMVILKL--LDKK-----GGFGVYRIPRYAADILNKCHDRIISPRAPKSFE-VVVPRVL
KGTFLV-DGEEKFILSSYRYKVNATQLILPVSDIKLIQDNFAVE--MQTKKLIEIYDNILRQVDKYFKLYDI---NKAKLHDGRSKFVELDDFGQDKVII
KILRGLHFGSDLNLKEIGFGTPLGQFQVIRLSNTAFIIFKSPTGLFNRKLYLK-
>tr|K1MLB3|K1MLB3_9LACO Uncharacterized protein OS=Lactobacillus crispatus FB077-07 GN=HMPREF9249_01635 PE=4 SV=1
TKNQEMFGMTIYPAEKSRKLIEKRKGFSTDIYGGYTGTAAAYMAIVRI--NKTKS----SQYKVIAVPMTKRAILNKAEKEILSKAGVISFD-IIKGKVP
YNQVVQ-DGNKKFLLKSAIYLCNAKQLVLSEEAMRVITGHW-SD--KQDQELLDVYDEILEKIDRYLPLFDI---RDNKLHKGREKFLKLNAE---KAII
QILKGLHDNSDTELKDIGITVPFGQLQ-ITLSSDTILVYQSPTGLFEKRVKIS-
>tr|A0A0B4EU74|A0A0B4EU74_9FUSO Uncharacterized protein OS=Fusobacterium necrophorum subsp. funduliforme B35 GN=C095_09135 PE=4 SV=1
EQHGGFFDQNIVDKEKGTGYIPIKSSLNTSKYGGYGSVTGTYFFLVEHTMK---GK---RIRTIEMMPLYLSKKIHSKEEKYCKKLELQKPS-VRLARIK
YNSLLKIN-GFPYHITGKTNDSYAIQLLLSKNYYEYLRKLYFCKEEIVGEKNIKLYTCILEKLYSHKLLNINYNKLKDILESEKENFLLLSEKKQAQILI
EIFTLLESNNFGNLESFGCGKKCGITKIIDKLEEVLLINQSPTGLFENSIDLKK
>tr|C0BCW4|C0BCW4_9FIRM Uncharacterized protein OS=Coprococcus comes ATCC 27758 GN=COPCOM_03005 PE=4 SV=1
-DGGAFWKQTIYSPREKSKLI-ATKSDPAEIYGGYSSQTFANFFVYEV--MKKKV----KQLRFGAVPAAIASKSDPDTEMYARGAKTAKVR-IVRARVL
KNTMIELY-GERFRIAGEKQVVRQMPLAIDEVYL--LKGVEIAAFEKAAESLVGFWDLLLEKLPVNY---PKLT-----------VQLKLGLLKHPKDIL
AATSIYKIEAEIDTKILGGNTFGGSLVFVDPKSKACFIDTTPAGLYEVKTKI--
>tr|E6MK09|E6MK09_9FIRM Putative CRISPR-associated protein, Csn1 family OS=Pseudoramibacter alactolyticus ATCC 23263 GN=HMP0721_2344 PE=4 SV=1
-EHGELSNQNICSAKAAQKAIKS-ERLNTQRYGGYNKYAGSYFFLVEH--TLKKN----RVRTIETMPLFLRDTIKTSKLKYCCELKLEAPS-IRVMKIK
MGSLLSVN-GAFVYLTGRSGKINGFQLILPQKWQDYIRLLITKD-GISGGKNIEFYDILVEKHTKTR---PNPI------------FIALDNQKQSDILL
EILKLTTFNSGA---AIGGKNQSGVST-ISSQKSVVLVHRSVTGIFEKQVDL--
>tr|C2KY78|C2KY78_9FIRM Uncharacterized protein OS=Oribacterium sinus F0268 GN=HMPREF6123_1447 PE=4 SV=1
-QHGSIANATLYSAK---KALKADEKMDVKKYGGYTSMSIAYYFIVHH--KEDKK----ENVTIEALPLYCKDKVEREEEKYCEELGYGEVN-IIRRKLK
IQSLLEFN-GYQVHLSGKTGNINAISLCLSTKWITYIKKLEAVN-VVTPEENIKLYNLLADKHANTR---PNAY------------FVTLEFGKQCEALL
QILSLTKISTEA---LIGESEHSGKIL-LKASDRPAVINQSPCGLYEKKEWI--
>tr|A0A0E9EM93|A0A0E9EM93_CHLTH Uncharacterized protein conserved in bacteria OS=Chlamydia trachomatis GN=ERS095036_05717 PE=4 SV=1
-GKGQLFDLTILKKSKIDKKKSLKDSCIAEKYGYFSTLMPAYFVVFKH--IDKNK----EVFGFDRIFIFDREKINSNEEKYLEDKGYNSPK-FI-RKVN
LKQKILLN-GYPYRIVGFTDNENSKQFYSDEEHLKYIKHLSFYNKERLNIEFIKLYEYFCERLNSRY---YNSK-----------KFKNLNLLDKAKLLL
EFLKIFKKTYGNKLDKNGNLSFEGLSMFFLVEKDIQFVDESVTGLFEKKEGL--
>tr|T5JGK2|T5JGK2_LACPN Uncharacterized protein (Fragment) OS=Lactobacillus plantarum EGD-AQ4 GN=N692_14645 PE=4 SV=1
TQHKELYGQTIYPRRKPGTLKAIKQDQPQELYGGYKNLTAAYMCIVKI--QARKRK--AAEYRVVRVATESLSALQQARRAYCRNSAPREFE-VLLDRVL
CHQMIISD-GQKYLLGSHAYKVNCMQLVLSNNSMKILSTSIVDLKQMTNEPLVQVYREILDVVNKYFTLYDDNS-FRENLNQFFDKFRTLPHRGQLETLT
LILRGLHANSD-KVQYGDQSTPLGSFQTIKLSKDSVIQYTSPAGLNVRTVKLR-
>tr|W7C9I0|W7C9I0_BROTH Uncharacterized protein OS=Brochothrix thermosphacta DSM 20171 = FSL F6-1036 GN=BTHER_07551 PE=4 SV=1
--------------------------MDTAIYGGYTAVNYASYALIQF--KKGRK----LKREIIGIPLAVQTRIDNSETAYIAEQIKSEVE-ILNGRIL
KYQLISNN-GNRLYIAGPSERHNARQLIVSDEAAKVIWLISKQADEYRLEHLEAVFEELIRKQAADY---QIFEKLIKKIEVNKVYFYSCTYNEKVKVIE
ELLKITQANATNDLKLLKMSNREGRLGSVSVALDFKIINQSVTGLYQSIED---
>tr|R7KAN2|R7KAN2_9FIRM CRISPR-associated protein Csn1 family OS=Acidaminococcus sp. CAG:917 GN=BN810_00504 PE=4 SV=1
--TAEFYDQTVYSPLGKKDLMPLKSKKPSDIYGGYSSVNPAYFVFVEE--RKGKNGK--INCVFDKIPVYVVWREKQDKDKYIKQTHGEDAK-II-KKIY
KYQKIVMD-GQTCYISGTKEQNNAQEFYVDAKYERMLFEIEKDKKEDLIKS-MNKYENLIDFIKCKM---PLYSDFANKLEEILSRYDNLSFKEKCELVK
NMLIVADTGAGVHYE----GHYYGKIRKTLTPKKILFIDESCTGLYSERKEL--