>seq_1
MWRLTIGEGGGPWLKSNNGFLGRQVWEYDADAGTPEERAEVERVRAEFTKNRFQRKESQDLLLRLQYAKDNPLPANIPTEAKLEKSTEVTHETIYESLMR
ALHQYSSLQADDGHWPGDYSGILFIMPIIIFSLYVTRSLDTFLSPEHRHEICRYIYNQQNEDGGWGKMVLGPSTMFGSCMNYATLMILGEKRNGDHKDAL
EKGRSWILSHGTATAIPQWGKIWLSIIGVYEWSGNNPIIPELWLVPHFLPIHPGRFWCFTRLIYMSMAYLYGKKFVGPISPTILALRQDLYSIPYCNINW
DKARDYCAKEDLHYPRSRAQDLISGCLTKIVEPILNWWPANKLRDRALTNLMEHIHYDDESTKYVGICPINKALNMICCWVENPNSPEFQQHLPRFHDYL
WMAEDGMKAQVYDGCHSWELAFIIHAYCSTDLTSEFIPTLKKAHEFMKNSQVLFNHPNHESYYRHRSKGSWTLSSVDNGWSVSDCTAEAVKALLLLSKIS
ADLVGDPIKQDRLYDAIDCILSFMNTDGTFSTYECKRTFAWLEVLNPSESFRNIVVDYPSVECTSSVVDALILFKETNPRYRRAEIDKCIEEAVVFIENS
QNKDGSWYGSWGICFAYGCMFAVRALVATGKTYDNCASIRKSCKFVLSKQQTTGGWGEDYLSSDNGEYIDSGRPNAVTTSWAMLALIYAGQVERDPVPLY
NAARQLMNMQLETGDFPQQEHMGCFNSSLNFNYANYRNLYPIMALGELRRRLLAIKS
>tr|A0A0D3HKM0|A0A0D3HKM0_9ORYZ Uncharacterized protein OS=Oryza barthii PE=4 SV=1
SRSMPFDQRSDPLLPSSGAMAVGGSTTLDLRSGHGGQAVAGT------------------------KLARYAKGHLQPSAVIVEDNQNVMEETILSSLRR
ALNQYSTLQAHDGHWPGDYSGILFIMPLL------------------------------NEDGGWGTQVLGQSTMFGSCLNYATLKLLGEALH--NNDAL
AQGRMWILSHGSATAAPQWAKIWLSFVGPITPTILEIREELYN-------------------------------------------------IPYSEIDW
KKARDCCAKEDLRYPCSWIQDIVWTYLNKYVDPMFNVWPFNKLREISLRNLMKHIYYEDENTKYIGLCPINKALNMICCWIEDPNSDAFKRHLPRIYDFL
WLAEDGMKAQVYDGCQTWETAFIVQAICSTGLVDEFSTTLEKAYGFLKNSQVLHDLPNGKSFYRHRSKGSWTLSTADNGWSVPDCTGETLQALLGLSKIS
PKLVGDPIKEKSLYDAVDCLLSFSNKDGTFSLYECTRTASWTEILNPSESFRNIVVDYPHVECTSSAIQGLISFTELYPGYRGEEIESCIKNAVMFIENK
QQNDGSWYGTWGICFTYGAFFAIRGLIAAGRNYENSQAIRNGCKFLLSKQLSAGGWGEHYSSSEIEVYVDSGSPHAVNTSLAMLALLYSG----------
------------------QEHVGCFNSSLYFNYPNYRNLYPIWALGEFRHRLVASK-
>tr|K3Y344|K3Y344_SETIT Terpene cyclase/mutase family member OS=Setaria italica GN=Si008629m.g PE=3 SV=1
MWKLKVSEG-GPWLRSSSGFLGRRVWEFDPDAGTPEERAEVDRLREDFTRHRFQRKESQDLLLRM--------LGNIP-SVKLENGAEVTEEILLTSLRR
ALNQYSTLQAHDGHWPGDYSGILFIMPIFIFALHVTMSVSIVISPEHRREILRYIYNHQNEDGGWGTLVLGRSNMFGSCLNYATLRLLGEVADGNN-EAL
AKARAWILSHGSATAIPQWGKIWLSIIGAYDWSGNVPVIPELWLVPYCLPIHPGRFWCFCRLVYMPMAYLYGKKFVGPITPTILALREELYSIPYDTIDW
IKARHSCAKEDLRYPRSQVQNLIFSCLNKFVEPMLNRWPGNKLREQALDNLMEHIHYQDETTKYIGISPIDKALNMICCWVESPNSDAFKQHLPRIYDYL
WLAEDGMKAQVYDGCQSWETAFIVQAFCSTDLVNEYGPTLARAYNFLKKSQVLENHPNYQSYYRHRSKGSWTLSTLDNGWSVSDCTAEALKALLLLSKTS
LNLSVDPIKEESLYDAIDCIISFMNKDGTFSTYECKRTFSWLEILNPSESFLNIINDYPYVECTSSVLEVLTFFKELYPLYRTKEIEKCIKDSAKFIENK
QCKDGSWYGTWGLCFTYGTLFAVKGLVAAGRTYNSSASIRKACNFLLSKQQISGGWGESYLSSETEDYVDGGTSHAVNTAWAMLALIYAGQVERDPLPLY
RAAKELINMQLDTGEFPQQEHVGCFNSSFYFNYGNYRNLYPIWALGEFRRRLLANK-
>tr|I1GYK5|I1GYK5_BRADI Terpene cyclase/mutase family member OS=Brachypodium distachyon GN=BRADI1G42000 PE=3 SV=1
MWRLKVSEG-GPWLRSVNNFLGRAVWEFEPDLGTPEERAEVERVRREFTEHRFQKKESQDLLMRMQYA-----QLD--PAIKLLDSAEVTEEIILTSLRR
ALSQHSSLQAHDGHWACDYSGILFIMPILVFALHVTGSLNAVLSIEHRREICRYIYNHQNEDGGWGTQVLGPSTMFGSCLNYVTLRLLGELD---NTDAL
TKGRAWILSRGSASAIPQWGKIWLSVIGLYEWSGNNAIVPELWLVPHFLPIHPGRFWCFCRMVYMPMSYLYGKKFVGPITPTIFAIREEIYNVPYHEIDW
NKARDTCAKEDLRYPRTLLQNVIWTCLNKCVEPVLNCWPINKLRDAALKNLIKHIHYEDEVTKYIGICPIVKALNMICCWSDDPNSDALKLHLPRIYDYL
WLAEDGMKAQVYDGCQSWEISFIVQAYCSTDLVAELGPTLRKAHEFIKSSQVLENHPDSEAYYRHRSKGSWTLSTADNGWSVSDCTAEAVKALLMLSKIS
PNLVGGPIEGERLHDAVDCLLSFMNKDGTFSTYECKRTTSLLEVLNPSESFLNIVVDYPSVECTSSVLQALIMFRELYPGYRKEEIGKCIKTSSKFIEDN
QRNDGSWFGTWGICFTYGAFFAVKGLVASGRTYENSSSIRKACTFLLSKQLSTGGWGETYLSSETEAYVAAIGPHAVNTAWAMLALIYAGQVERDPTPLF
HAAKELINMQLETGGFPQQEHVGCFNCSLYFNYANYSYLYPIWALGEFRRRLVGKR-
>tr|M1S227|M1S227_ORYSJ Terpene cyclase/mutase family member OS=Oryza sativa subsp. japonica GN=OSC6 PE=2 SV=1
MWRLKVAEG-APGLRSCNGFLGRAVWEFDPNAGTPEERAEVERMRREFTLHRFERREAQDLLMRM--------QVDV-PASKLVDSTQVTEQIILASLRR
ALTQHSALQAHDGHWPGDFSGIMFIMPILIFALYITGSLDAVLSSEHRREICRYIYNHQNEDGGWGTQVLGPSTMFGSCLNYVTLRLLGQER---SIDAL
TKGRAWIISRGSAAAVPQWGKIWLSVIGLYDWSGNNAIIPELWLVPHFLPIHPGRFWCFCRLVYMPMAYLYGKKFVGAITPTILEIREELYSVPYNEINW
KNARNNCAKEDLRYPRSFVQNVIWTGLNKVVEPILSLWPFNTLRHAALNNLLKHIRYEDESTKYIGICPINKALDMICCWIDNPNSDAFKLHLPRIYDYL
WLAEDGMKAQVYDGCQSWETAFIVQAYCSTDLVNEFSQTLTKAHEFIKKSQVLENHPDYEAYYRHRSKGSWTLSTADNGWCVSDCTAEALKALLMLSKIS
QDLVGDPIDGERLYDAVDGMLSFMNEDGTFSTYECKRSTPWLEVLNPSESFLNIVVDYPSVECTSSVLQALIMFSELNPVYRKEEIGNCIIKSSKFIENK
QRKDGSWFGTWGICFTYGTFFAVKGLAAAGRTYENSSSIRKACNFILSKQLSTGGWGETYLSSETEVYVEASRPHAVNTAWAMLALIYAGQVEIDPTPLY
HAAQELINMQLETGEFPQQEHVGCFNCSFSFNYSNYRNLFPIWALGEFHRRLVLRK-
>tr|I1PTL9|I1PTL9_ORYGL Terpene cyclase/mutase family member OS=Oryza glaberrima PE=3 SV=1
MWRLKVSEG-SPGLRSVNGFLGRCVWEFHPDAGTPEERAEVERVRREFTAHRFERRESQDLLLRM--------QVDA-PTDELVYSTQVTEEIILASLRR
ALTQHSALQAHDGHWPGDFSGIMFIMPILIFALYITGSLDVVLSAEHRREICRYIYNHQNEDGGWGKEVLGLSTMFGSCLNYVALRLLGEER---SNDAL
TKGRAWILSHGSAAAIPQWGKIWLSVIGLYDWSGNNAIIPELWLVPHFLPIHPGRFWVFCRLIYMPMAYLYGKKFVGTITPTILQIREELYSVPYNEINW
IIARDTCAKEDLRYPRSFVQNVIWTCLNKIVQPILNLWPLNNLRHVALNNLMKHIRYEDECTKYIGLCPINKALNMICCWIDNPNSDAYRLHLPRIYDYL
WVAEDGMKFEVYDGCQSWETSFIVQAYCSTDLVNEFSQTLIKAHEFIKKSQVLENTPDNEAYYRHRSKGSWTLSTADNGWCVSDCTAEALKALLMLSKIS
PDVAGDAINGERLYDAVDGMLSFMNKDGTFSTYECERTTHWLEVLNPSETFLNIIVDYPSVECTSSVLQALIMFSECYPVYRKEEIGKCIKNASKFIENK
QRKDGSWFGTWGICFTYGTFFAIKGLVAAGRTYENSSSIRKACNFILSKQLSTGGWGETYLSSETEVYVGASRSHVVNTAWAMLALIYAGQVERDPSPLY
HAAKELINMQLETGEFPQQEHVGCFNSSFYFNYSNYRNLFPIWALGEFRRRLVLRK-
>tr|A0A0D9VFG1|A0A0D9VFG1_9ORYZ Uncharacterized protein OS=Leersia perrieri PE=4 SV=1
MWRLKISEG-APGLRSCNGFLGRAVWEFDREAGTPEERAEVERVRREFTLHRFERRESQDLLMRMQI------QVNLPPASKPIKSEQVTEEIILTSLRQ
ALVQHSDLQAHDGHWPGDYSGIMFIMPIL------------------------------NEDGGWGTQVLGPSTMFGSCLNYITLRLLGEER---SNNAL
TKGCAWIISHGTAAAIPQWGKIWLSVIGLYDWSGNNAIIPELWLLPHFLPIHPGRFWCFCRLIYMPMAYLYGKKFIATITPVILELRQELYSLPYKEINW
LKARDTCAKEDLRYPRTFVQNAVWTCVNKVVEPILNQWPFNKLRDAALNNLMRHIRYEDESTNYIGICPINKALDMICCWIDNPHSDAFKLHLHRIYDYL
WVAEDGMKAQVYDGCQIWEIAFIVQAYCSTDLANEFSQTLRKAHDFIKKSQVLENLPENEAYYRHRSKGSWPLSTVDNGWCVSDCTGEALKALLMLSKIS
PDLVGEPINGERLYDAVDGMLSFMNKDGTFSTYECKRTTPWLEVLNPSETFLNIIVDYPSVECTSSVLQALVMFSELHPVYRKEEIGKCIRSSLRF----
--------GTWGICFTYGTFFAVKGLVSAGRTYENSPAIRKACHFLLQKQLSTGGWGETYLSSETEVYVEASKPHAVNTAWAMLALIYAGQVERDPRPMY
HAAKELINMQLETGEFPQQEHVGCFNCSFYFNYSNYRNLFPIWALGEFHHRLVLRN-
>tr|J3ME79|J3ME79_ORYBR Terpene cyclase/mutase family member OS=Oryza brachyantha GN=OB06G23230 PE=3 SV=1
MWRLKVGEG-AAGLRSVNGFVGRAVWEFDPEAGTPAERAHVERLRREFTERRFQKREAEDLLMRLQFA--------QPRASKLVDSDEVTEETILASLRR
ALAQHSSLQAHDGHWPCDFSGISFNIPILIFSLYVTESLNAVLSSEHRREICRYIYNHQNEDGGWSSYVIGESTMFGSCLNYVTLRLLGEDK---KNDAL
TKGVAWITSHGTAAAMPQWGKIWLSVIGLYDWSGNNPIIPELWLVPQFLPIHPGRFWCFCRMVYMPMSYLYGKKFVGKITPTILAIRDEIYTAPYKEINW
KMARNMCAKEDLRYPRSFIQNIVWTCLNKVVEPVLNVWPVNKLRGAALETLMKHIRYEDESTNYINLCPIIKGLNMICCWVDNPNSDAFKLHLPRIYDFL
WVAEDGMTAQVYDGSQTWQTSFIVQAYCSTDLVNEFHETLRKAHEFIKKSQVLENHPESGDYYRHRSKGSWTLSTADNGWSVSDCTAEALKALFLLSKIS
PDLVGDPIEGERLYDALDCLLSFMNKDGTFSTYECKRTTPLLEVLNPSESFLNIVVDYPSVECTSSVLQALIMIRELYPVYRSGEIEKCIKSASKFIERE
QRKDGSWFGTWGICFTYGTFFAIKGLVSAGRTYENSSSIRKACNFLLSNQLSTGGWGESYLSNETTVYVNANRPHAVNTAWAMLALIYAGQAERDLTPLY
DAAKELINMQLESGEFPQQEHVGCFNSSFCYNYGNYRNLFPIWALGEFRRRLVARK-
>tr|C5YJE0|C5YJE0_SORBI Terpene cyclase/mutase family member OS=Sorghum bicolor GN=Sb07g007030 PE=3 SV=1
MWRLKVAEG-GPWLKSCNNFRGRVVWEFDPELGTPEERAEVERVRREFTERRFEKRESSDLLLRMQYA-----QVD--PPTKLAENVEVTEEIILAALRR
ALDQHSSLQAEDGCWPADYSGILFIMPLLVFALYTTGSLDTVLSKEHRREICRYIYNHQNEDGGWGKQVLGPSTMFGSCLNYVALRLIGEKP---TNAAL
TKGRQWILSHGSAAAIPQWGKIWFSVMGLYDWSGNNPIVPELWLVPHFLPIHPGRFWVFCRMVYLPMAYLFGRKFIGTITPTILELRDELYSVPYSEVDW
EKARDTCAKVDLIYPRTMAQNLVWTCLNKVIEPMLNCWPVNKLRDIALKNIMKHIHYEDETSKYICTCPINKALDMICCWAENPNSDSFKKHLPRIYDML
WIAEDGMKAQVYDGNPTWETSFIVQAYCSTGLVNEIGSTLRKAHEFIKSSQICENHPDYKTYYRHKSKGSWTLSTADNGWSVSDCTAEAVKALMLLSKIS
PDLVGEPIEGQSLYNAVDCLLSYVNNDGTFSTYECKRTTPLLEVLNPSESFINIVVDYPSVECTSSVLQALIMFRDLDHGYRKEEIGNCIESATKFIEKE
QRKDGSWFGSWGVCFTYGSFFAIKGLAASGRTYKNSDTIRKACNFLLSKQLHTGGWGESYLSSETEEYVDASRPHAVNTAWAMLALVYGGQVERDPTPLY
KAAKVLINMQLESGDFPQQEHVGCFNSSLYFNYGNYRNLYPIWALGEFRQRLLARK-
>tr|A0A096SMN7|A0A096SMN7_MAIZE Terpene cyclase/mutase family member OS=Zea mays GN=IDP628 PE=3 SV=1
MWRLKIGER-NPLLRSPNGFLGREVWEFDPAAGTPEERAEVDRLRQEYTRNRFTRRQCSDLLMRMQYAKQN--NTN--LAIKIDQ-DSDTEETILITLRR
ALNQYSSLQGPAGHWPGDYGGISFILPLMIFALHVTRSMDEVLSIEHIREICRYIYNMQNEDGGWGTHTLGPSSMFGTCVNYATLRILGEVLDGEN-DAL
SKGRSWILSHGSATAAPQWAKIYLSMIGVYDWAGNNAIIPELWMLPHFLPIHPGRFWCFCRMVYMPMAYIYGKKFVGPITTTILEIRNELYNIPYNKINW
NKACNSCAKEDLIYEPSWLQSIAMAYLNKFIEPLSNLWPMNKLRERAMSDLMEHIHYEDETSNYVGLCPINKALNMICCWIEKPNSNEFRQHLPRIHDFL
WLGEDGMKSKVYVGCHSWETALIVQAFCSTGLTEEFCSTLQKAHQFLKNAQVIKNIPDYKSYYRERTKGSWTLSNGENFWPIADTTAEALKAILLLSNIP
SELVGDPIKQERLYDAVDCLLSFVNKDGTLSSAECKRTTSWVEFINPSESFRNIIVDYPYPECTSSLIQALVLFRGKHPIYRRDEIDKIIKSGASFIEKV
QRKDGSW-GSWAVCFTYATFFAIKGLVAAGRTYRNSLAIRKACNFLLSKQLGTGGWGENYLGCQI-EYVDSGSPHGVNTAQAMLALLYAGQVEQDPAPLY
RAAKELINMQMENGEFPQQEIVGNFNSSLFFNYPNYRNLFPIWALGEFRRRLVAKK-
>tr|C0PGA6|C0PGA6_MAIZE Terpene cyclase/mutase family member OS=Zea mays GN=LOC100285643 PE=2 SV=1
MWRLTVAEG-GPWLRSTNGFVGRAVWEFDPDLGTPEERDEVERVRQEFSDHRFQRRESADLLMRMQCAKQNRS-LP-----RIKLGDEHTEEIVLSSLRS
ALDQFSSLQASDGHWPGDFSGIMFIMPGLIFALYVTGSLNVVISPEHRHEICRYIYNHQNEDGGWGTLILGSSTMFGTCSNYITLRLLGEEPYANN-SVL
AKGRAWILSHGGATLIPQWGKIWLSVLGLFDWSGNNPIFPELWSIPQFLPFHPGKFWCFARMVYLPMAYLYGKKFVGPITPTILALREEIYDTPYGKIDW
SDARSKCAKEDLICPRTLLQNVIWTSLYRCVEPVLSSWPINKLRERALGNIMEHIHYEDENTQYLCICPVNKALNMVCCWVEDPNSDAFKRHLARIPDFL
WISEDGMKAQVYDGCQSWETSFIIQAFCATDLVNDYGSTLQRAYEFMKNSQVMRNHPGDQRYHRHRSKGSWTLSSADNGWAVSDTTGEALKAVLLLSKIS
NNLVGDPIERERLHDAIDCLLSFANKDGTFSTYECKRTYSWLEILSPCETFPNIVVDYPYPECTSSVLQALILFKDLYPGYRTEEIEALVRSAATFIETK
QQEDGSWLGNWGICFTYGAFFSIKGLVASGRTYKNSPCIRKACHFILSKQLSTGGWGESHIAIET-VNLKGDRAHAVNTAWAMLALIYAGQFERDPTPLH
RAAKELINMQLETGEFPQQEHVGCFNCSLYFNYPSYRNLFPIWALGEYHRGLRAKK-
>tr|Q0IT98|Q0IT98_ORYSJ Terpene cyclase/mutase family member OS=Oryza sativa subsp. japonica GN=Os11g0286800 PE=3 SV=1
MWKLKFGEG-NPLLRSSNGFLGRETWEFDPNGGSPEEHAVVERLRRDFTRNRFTQRECSDLLMRMQF------YSK--HVSNLKD-SSETEEVLLTSLRR
VLDQYSSLQAPDGYWPGGYSGILFILPLMIFALHVTKSLNDVLSSEHIREICRYIYNIQNEDGGWSTHTLGPSSMFGSCVNYATLRLLGEVLDEHN-DGL
SKGRAWILSHGSATVAPQWAKIYLSVIGVYDWSGNNPIIPELWLLPHFLPIHPGRFWCFCRMVYMPMSYIYAKRFIGPITPTILALREELYDVPYNKINW
NNARISCCKDDIIYPPSWFQNIAMASLHKFMEPLFNMWPMNKLRKRALTNLMDHIHYEDENSNYVGLCPINKVLNMICCWIENPNSNAFRRHVPRIHDFL
WLAEDGMKSKVYVGSRCWDTALIVQAYCSTGLTQEFSETIKKAHDFIKNAQVTKNCPNYKRYYRERSKGSWTLSNGENGWPIADTLAECLKAVLLLSKIP
PTQVGDPIQEQRLYDAIDCLLSYVNKDGTLSSAESKRTTPWVEFINPSESFRNIIVDYPYVECTSSLIQALILFKGVHPGYRREEIDRIIKNGVLFIEKK
QKNDGSW-GSWAVCFTYATFFAIKGLVAAGRTFQNSLSIRKACNFLLSKQLSTGGWGEDYLGCQV-EYIDSGRPHVVHTAWGMLGLIYAGQVELDPAPLY
RAAKELINMQLETGEFPQQEILGSFNSSLFFNYTNYRNLFPIWALGEFHRRLLAKR-
>tr|W5DZA6|W5DZA6_WHEAT Terpene cyclase/mutase family member OS=Triticum aestivum PE=3 SV=1
MWRLKIGEG-RPWLHSASGFLGRQVWEFDRDAGTPEERAEVERLREDFTKHRYHKRESQDLLLRL--------PANIPTTRVVEKGTQVTEKMITTSLRR
ALHQYSTLQAHDGHWPGDVSGLMFIMPMLIFSLYVTGSLNIVLSSEHQREIRRHIYNHQNEDGGWGTHVWGPSSMFGSCLNYVALRL-GEMLDGDN-DVL
TKGRAWILSHGSATGVPQWGKIFLSIIGVYDWSGNNPIIPELWLLPYFLPIHPGRFWCHCRLVYMSMAYLYGKRFVGPITPTIMALREELYNIPYDNVDW
GKASNYCAKEDLHNPRSQMQNIVSFCLNKFVEPMLNWWPANKLRGRALSKLMEQIHYNNEITEYITSSHVDKILNMICCWVENPNSNAFKKHLPRVYDHL
WIAEDGMKAKICDGCQSWETPFIVQAICSTDLIAEFGPTIKKAHEFMKNSQILGNFPSYESFYRHRSKGSWTLSTIDHGLSISDCTAETLKALLSLSKIS
PNLVGDPIEEQRVYDAIEFLLSLMNKDGSFCAYEHRRTSAWLEILNPSESFKNIVIEYPSCECTASVVDALILFKELYPQYRGDELGKCIKGAAKFIEGK
QLNDGSWYGSWGICFTYGTLFAIKGLIAAGRNYHNSSSIRKACNFLLSKQQSTGGWGESYLSNYTGEYVDSGTPHTVETAWAMLGLFYGGQTEIDRVPLY
RAAQVLMSMQLDTGEFPQQEHVGSANSAFYFNYPNYRNLYPIMALGEFRRRLVASD-
>tr|I1NX58|I1NX58_ORYGL Terpene cyclase/mutase family member OS=Oryza glaberrima PE=3 SV=1
MWRLKVAES-TPLLRSTNGFLGRAVWEFDPDHGTPEDRADVERVRREFTDHRLHHRESADLLMRMQYIKQNKH-YRIP-PVNNKLGKEETEEIAMASLRR
ALDEFSSLQADDGHWPGDFSGVMYIMPGLIFALYATGSLDTIISPEHRREICRYIYNHQNEDGGWGSLILCSSTMFGTCSNYITLRLLGEETS--N-EQL
AKGRIWIISHGGATLVPQWGKIWLSILGVYEWAGNNPIFPELWLTPQFLPFHPGKFWCLTRMVYLPMAYLYGKKFVGPTTPTILALREEIYSAHYLTIDW
AQARSACAKEDLVCPRTRLQNAVWSWLYKWVEPVMSSWAMSKLRGRALDRLMEHIHYEDENTQYLCICSVNKALNMVCCWAEDPNSDAFKRHLARVPDFL
WLSEDGMKAQVYDGCQSWETAFIIQAFCATDLVNEYASTVQRAHEFLKNSQVVRNHPGDQSYHRHRSKGSWTLSSADNGWAVSDTTAEALKAVLLLTKIS
INVVGDPIERERLHDAVDCLLSFVNKDGTVSTYECKRTSTWIEILNPCESFPNMVVDYPYPECTSSVLQALVLFKELCPGYRTEEIEKCVRNATMFIENT
QGEDGSWLGTWGVCFTYGAFFSVKGLIAAGRTYENSSSIRKACDFIMSKQLNTGGWGESHVSNET-VNIKGDHAHAVNTAWAMLTLIYAGQMERDPAPLH
CAAKELINMQLETGEFPQQEHVGCFNCSAFFNYPNYRNLFPIWALGEYCNRLRSER-
>tr|W5GH77|W5GH77_WHEAT Terpene cyclase/mutase family member OS=Triticum aestivum PE=3 SV=1
MWMLKVGEG-GPWLRSTNGFLGRAVWEFDASAGTPEERAEVERVRQEFTDGRFRRRESADLLMRLQCSKENKH-RRLP-PM-EKLEKDETEDTVLVSLRR
ALDQFSSLQSDDGCWPGDFSGIMFVMPGLIFALYVTRSLNTVVTAEHRREICRYIYNHQNEDGGWGSLILGSSSMFGTCSNYITLRLLGEELDG-N-TAL
AKGRGWISSHGSATLVPQWGKIWLSILGMYDWSGNNPIFPELWLAPQFLPFHPGKFWCLCRMVYLPMAYLYGRKFVGPITPTILAIREEIYDVPYDQIDW
GMSRNACAKEDLVCPRTTLQNAVWTSLYKCVEPVLSSWPINKLRDRAQKNLMEHIHYEDDNTQYLCICSVNKALNMVCCWAEDPNSEAFKRHLARVPDFL
WISEDGMKAQVYDGVQSWETSFIIQAYCATGLVSEYGPTLERANAFMKKSQVLWNHPGDQSYHRHRSKGSWTLSSADNGWTVSDTTAEALKAVLLLSKIS
RNIVGDPIERERVHDAVDCLLSFVNKDGTFSTYECKRTSTWIEILNPCESFPNMIVDHPYPECTSSVLQALMLFKELHYGYRTKEIEKCIRDAATFIESR
QGEDGSWLGTWGVCFTYGAFFSVKALVAAGRTYESSSSIRKGCHFILSKQLSTGGWGESHVSNET-VNIEGDRAHAVNTAWAMLTLIYAGQMERDPAPLH
RAAKELINMQMDTGEFPQQEHVGCFNCSLFFNYPNYRNLFPIWALGEYRRRLCSKS-
>tr|A0A0E0MER1|A0A0E0MER1_ORYPU Uncharacterized protein OS=Oryza punctata PE=4 SV=1
MWRLKIGQG-NPLLRSPNGFVGRETWEFDPDAGSPEERAEVERLRHDFTRNRLTCRECDDLLMRRQERTELFYYTN--IINKLKD-SSETEEVLLTSLRR
ALNQYSSLQGEDGHWPGGYSGISFILPLL------------------------------NEDGGWGTSTLGPSSMFGSCVNYATLRLLGEVLDEDN-NAL
FKGRAWILSHGSATAAPQWAKIYFSIIGVYDWSGNNPIIPELWMLPHFLPIHPGRFWGFCRMVYMPMSYIYAKRFVGPITPTILAMREELYNVPYNKINW
NDARCSCCKDDIIYPPSWLQNVTMSSLHKFVEPMFNIWPMNKIRQRALANLMDHIHYEDENSYHIGLCPINKVLNMICCWIENPNSLAFKKHLPRINDYL
WIAEDGMTSKVYSGCQSWETAFIIQAYCSTGLTKEFGTTVRKAQDFLKIAQVTQNCPSYKSFYRERSKGSWTLSNGENCWSIPDTTAECLKALLLLSKIP
SNDVGDPTKEWRLYDAVDVLLSYVNKDGTLSSIERKRTTSWVEFLNPSESFRNIIVDEPHTECTSSLIQALILFKEMYPSYRAEEIQKIVKSGASFIEKM
QLKD--------------------GLVMAGRTYQNSSSIKKACNFLLSKQLNTGGWGESYVGSQI-EYVDTGKPHVVNTALAMLGLIYAGQVELDPAPIY
RAAKELINMQLDTGEFPQQELVGNFNSSLFFNYPNYRNLFPIWALGEFRCRLLAKN-
>tr|W5BLQ3|W5BLQ3_WHEAT Terpene cyclase/mutase family member OS=Triticum aestivum PE=3 SV=1
--------------------------------------------------------------------------MHIP-TLKLENTIEVTEEIISASLTR
ALNQYSTLQAHDGHWPGDYSGILFIMPIFVFSLYVTGSLNTVLSFEHKHEICRYIYNQQNENGGWGKQVLGPSTMFGTCMNYVCLMLLGEKLNGDL-DAL
VKGRSWIISHGSATAIPQWGKIWLSIIGVYDWLGNNPIIPELWLVPDFLPVHPGRFWCYTRLVYMSMAYLYGIKFVGPLSPTILALREDLYSVPYMNIDW
DKARDSCAKEDLHYPRSQAQNLIFGCLNKFVEPILNCWPANKLRERALSNLMKHIHYEDETTKYVGICPITKALNMICCWVENPNSDAFKQHLPRFYDYL
WLAEDGMKAQVYDGCHSWEIAFIIQAYCSTNLIGEFGPTIKKAHEFMKNSQVLSNHPNYERYYRHRSKGSWTLSSVDNGWSVSDCTAEAVKALLLLSKIS
PDLVGDPIKQERLYDAIDCILSFMNKDGTFSTYESKRTFSWLEVLNPSESFRNIVVDYPSVECTSSVLDALIIFQEVHPLYRRNEIEKCIRDAAKFIENN
QKNDGSWYGTWAICFTYGTMFAVRGLVAAGRTYDNSYPIRKACTFLLSKQQSTGGWGESYLSSHNEDYVDSHKPNVVNTSFAMLALIYAGQVERDPVPLF
QAARQLINMQLETGEFPQQEHVGCFNSSFYFNYANYRNLYPIMALGELHRRLLAIK-
>tr|T1MWU9|T1MWU9_TRIUA Terpene cyclase/mutase family member (Fragment) OS=Triticum urartu PE=3 SV=1
----------------------------------------------------------------LQYA-----QAD--PAIKLVDSAEVTEGTMLISLRR
ALSQHSALQAHDGHWACDFSGIMIIMPILIFALHVTGLLHTVLSTEHRREICRYIYNHQNEDGGWGTQVLAPSTMFGSCLNYVTLRLLDEVD---N-EAL
TKGRAWILSRGSIVAIPQWGKIWLSVIGLYEWSGNNSIIPELWLVPHFLPFHPGRFWCFCRLVYMPMSYLYGKKFVGPITPTILAIREELYSTPYHEVNW
NKARVTCAKEDLRQTQSLLQNVIWTCLNKFVEPALNCWPINKLRAKALKNLMKHMHYEDESTQYIGISPINKALDMICCWIDDPNSDALKLHIPRIYDYF
WLAEDGMKAQVYDGCQSWEIAFIIQSYCSTDLVNEFIPTLKKAHEFLKSSQVLENHPDSEAYYRHRSKGSWTLSTADNGWAVSDCTAEALKALFLLSKIS
PNLVGEPIKGQRLYDAVDCLLSFTNKDGTFSTYECKRTTSLIEVLNPSESFLNIMVDYPSVECTSSVLEALIMFSEIYPGYRKAEIEKCIKNASMFIEDS
QRKDGSWFGTWGICFTYGTFFAVKGLIASGSTYENSSFISKACNFLLSKQLSTGGWGETYHSSETEAYVVATSPHAVNTAWAMLALIYAGQVERDPTPLY
HAAKELMNMQLDTGEFPQQEHVGCFNCSFYFNYGNYCNLYPIWAIGEFRRRLLEK--
>tr|B9GB84|B9GB84_ORYSJ Terpene cyclase/mutase family member OS=Oryza sativa subsp. japonica GN=OsJ_34282 PE=3 SV=1
MWRLKVAQG-GALLRSTNGFAGRAVWEFDPDHGTPEDRANVERVRRDFTDHRLRRPESADLLMRMQFARENNH-DRIP-PAVNKLGKEQTEETVMASLRR
ALDEFSSLQADDGHWPGDLSGAIFIMPVLIFSLYATGSLDTVISSEHRREICRYIYNHQNEDGGWGMLILGSSTMFATCLNYVTLRLIGEEPS--N-EQL
ARGHAWIISHGGATLVPQWGKICLSIIGVYEWSGNNPIFPELWLAPQFLPFHPGKFWGPTRVVYVPMAYLYGKKFVGPITPTILALREEIYTDPYHTIDW
AQACNACSKEDLVCPRTLLQNVVWTSLYKWVEPVLGSRPMNKLRERALDRLMEHIHYEDENSQYLCLCPVNKALNMVCCWVEDPNSDSFKRHLARIPDFL
WLSEDGMKAQIYDGCQSWETAFIIQAFCATDLVNEYGSTVRRAHEFMKNSQIMRNHPGDQSYHRHRSKGSWTLSSADNGWAVSDTTAEALKAVLLLEKIS
SNVVGDPIEIERLHDAVDCLLSFVNKDGTLSTYECKRTYTWIEVLSPCESFPNIVVDYPFPECTSSVLQALVLFKQLHPSYRIKEIEKCVRNAAMFIEST
QGEDGSWLGTWGVCFTYGAFLSVKGLIAAGRTYENSSSIRKACDFILSKQLETGGWGESYVSNIT-VNIKDDQAHAVNTAWAMLALICAGQMERDPAPLH
RAAKELINMQLETGEFPQQEHVGAFNACLFFNYPNYRNLFPIWALGEYCRHLHSTR-
>tr|A0A0D9XRJ7|A0A0D9XRJ7_9ORYZ Uncharacterized protein OS=Leersia perrieri PE=4 SV=1
MWKLKIGEG-NPLLRSPNGFLGREVWEFDPNAGTPEERAEVERLRNDFTRNRFTQRESSDLLMRMQE-----------------N-SSQTEEVLLTALRR
VLKQYSCIQGEHGHWPGGYNGILFILPLT------------------------------NQDGGWSTHTLGPSTMFGSCVNYATLRLLGEEMHGDN-VAL
SKGRAWILSHGSAAAAPQWAKIYLSVIGVYDWSGNNPIIPELWMLPHFLPIHPGRFWCYCRMVYMPMSYIYAKKFVGPITPTILAIRDELYNVPYNKISW
TCARSSCCQDDIIYPPSWLQCVAMASLSKFVEPVFNMWPMKKIRQRALSNLMDHIHYEDETSNYIGLCPINKVLNMICCWIENPNSDAFKQHLPRINDFL
WLAEDGMKSKVYNGCQCWETALAVQAYCSSGLAQEFGATLKKAHDFIKNAQVIKNFPNYKSFFRERSKGSWTLSNGENCWPMADCTAECLKAVLLLSKIP
SNHVGDPIEEERVYDAVDCLLSFVNKDGTLSSAECQRTSFWVEFINPSESFRNIIVDYPYVECTSSLIQALTLFKGIYPSYRHEEIEKIIESGALFIEKQ
QRKDGSWCGSWAVCFTYATFFAIKGLTAAGRTYQNSSSIRMACDFLLSKQLSTGGWGENYISCQV--------------------------VELDPSPLY
CGAKELINMQLETGEFPQQEIVGNFNSSLFFNYTNYRNLFPIWAIGEFHRRLLAKS-
>tr|K7V3T4|K7V3T4_MAIZE Terpene cyclase/mutase family member OS=Zea mays GN=Zm.26912 PE=3 SV=1
MWRLKIGGE-GPWLRSASGFTGRQVWEFDPDAGTQDEIAEVERLRREFTERRRFDKRAV-----------------------------------------
--------------------AQDLLLRMQVFALHVTGSLNTVLSAEHRHEICRYIYNHQNEDGGWGMQEVGPSTMFSSCLNYVTLRLLGEACA--QHDAL
AKGQAWILSHGSAAAIPQWGKIWLSVIGLYDWNGNNSIVPELWLVPYSLPFHPGRFWCFCRLIYMPMAYLYGKKFVGPITPTILSIRNEIYKIPYDEVDW
NKARDTCAKEDLLYPRTFVQNVIWTCVNKIVEPLLNLWPAKMLRDTALKNIMNHIHYEDESTRYLCVCPVNKALNMICCWVENPNSDAFKRHLPRIYDYI
WLAEDGMKLKVYDGTQAWDTAFIVKAYCSTDLVHEFSPTLRKAHEFIKSLQIPENQPDHENYYRHRSKGSWAHSTLDNGWSVSDSTAEAIQALLLLSKFS
SNLVGDPIKEERLFDAVDCLLSFMNKDGTFSTYERKRTASLLEVLNPSETFLNIVVDHPSVECTSSAIQALVMFREMYPRYRDQEIKKCIKGASKFIESK
QQKDGTWFGTWGVCYTYGTLFAVQGLVVAGRTYENSSSIRKACRFLLSKQLITGGWGETYPSNGTAVYAEASSPHVVNTAWAMLALIYAGQVQRDPTPLY
GAAKELINMQQESGEFPQQEHIGSFNCSFYFNYGNYRNLFPIWALGEFRRRIVAEK-
>tr|C5Z987|C5Z987_SORBI Putative uncharacterized protein Sb10g029175 (Fragment) OS=Sorghum bicolor GN=Sb10g029175 PE=4 SV=1
------------------------VWEFDADAGTPEERAEVERLRQDFTRHRFQKKESQDLLLRMQETLNIHYVENIP-AVKLEKGAEVTEEILLTSLKR
AMNQYSALQAHDGHWPGDYSGILFIMPIF------------------------------NEDGGWGTQVLGPSSMFGSCLNYATLRLLGEAPNGEN-DAL
AKGRAWILTHGSATAIPQWGKIWLSIIGAYEWSGNNPIIPELWMVPYFLPIHPGRFWCFCRLVYMPMAYLYGKKFVGPITETILELREELYSIPYDTIDW
NKARHSCAKDDLRYPRSELQNIIFSCLNKFVEPMLNCWPVNKLREKALDNLMEHIHYQEKTTKYICICPIDK---------KNPNSDAFKKHLPRIYDYL
WLAEDGMKAQVYDGCQSWETAFIVQAFCSTDLANEFSQTLERAYDFIKKSQVLENHINYESYYRHKSKGSWTLSTADNGWSVSDCTAEALK---------
------------------------NKDGTFSTYECKRTVSWIEILNPSESFINIVVDYPSVECTSSVLEALTLFKELYPPYRAKEIKKCIKDCAMFIENK
QRKDGSWYGTWSICFTYGTMFAIKGLVAAGSTYDTSSCIRKACKFLLSKQQITGGWGESYLSSETEDYVDGGTPHAVNTAWAMLALIYAGQVERDPVPLC
HAARELINMQLETGEFPQQ--------------------------------------
>tr|J3N7J2|J3N7J2_ORYBR Terpene cyclase/mutase family member OS=Oryza brachyantha GN=OB11G17780 PE=3 SV=1
-------------MGSPGGRCGSSS-------PAPARRRSAPRWRTSAAT-----------SPATASRAGRATVTT--LVNKIED-CSETEEVVLTVLRG
VLNQYSSLQSEDGHWPGGYCGISFILPLMIFALHVTGSINDVLSSEHIREICRYIYNMQNEDGGWGTSTLGPSSMFGSCVNYATLRLLGEVPDEQN-EGL
SKGRAWILSHGTATAAPQWAKIYLSVIGVYEWKGNNPIIPELWMLPHFLPIHPGNFWGFCRMVYMPMSYIYAKRIVGPITPTIMAMREELYSVPYNKIDW
DDARRSCCKVDMIYPPSWLQKVTMASLHKFVEPVFNMWPMNKIRQRALTNLMDHIHYEDENSNYIGLCPINKVLNMICCWVENPKCSGFKRHLPRINDYL
WIAEDGMTSKVYSGCQSWEMAFIVQAFCSTGLTHEYGETVRKAYDFLKNSQVIQNCPNYKSFYRERSKGSWTLSNGENSWSIPDTTAECLKALLLLSKIA
SNDIGVPIKEERLYDAVDVLLAYTNKDGTLSSIETKRTTSWLEFLNPSESFRNIIVDEPHPECTSSLIQALVSFKEIYPGYRHKEIEKIIKSGALFIEKT
QRKDGSW-GSWAVCFTYGTFFAIKGLVAAGRTYQNSSSIRNACNFLLSKQQTTGGWGENYLGCQV-EYVDNGRPHVVNTCLAMLGLLYAGQFELDPLPLY
RAAKELINMQLDTGEFPQQEIVGNFNSSLFFNYPNYRNLYPIWALGEFRRRLLAKM-
>tr|B9F2M9|B9F2M9_ORYSJ Terpene cyclase/mutase family member OS=Oryza sativa subsp. japonica GN=OsJ_05325 PE=3 SV=1
MWRLKVAEG--ALLRSTNGFLGRAVWELDPDHGTPEDRADVERVRREFTDDRLRRRESADLLMRMQFAKQKKL-DSIP-PA-VKLGKEQTEEIAMASLRR
ALDEFSSLQADDGHWPGDFSGVMFIMPGLM----------------------------------------------------------------------
-------------------------LGVYEWAGNNPIFPELWLAPQFLPFHPGKFWCLTRMVYLPMA-YLYGKKFVGPTTPTILALREEIYPVHYLTIDW
AQARSACAKEDLVCPRTRLQNAVWSWLYKWVEPVMSSWAMNKLRGRALDALMEHIHYEDENTQYLCICSVNKALNMVCCWAEDPNSDAFKRHLARVPDFL
WLSEDGMKAQVYDGCQSWETALIIQAFCATDLVNEYASTVQRAHEFMKNSQVVRNHPGDQSYHRHRSKGSWTLSSADNGWAVSDTTAEALKAVLLLTKIS
SSMVGDPIERERLYDAVDCLLSFVNKDGTISTYECKRTSTWIEILKPCESFPNMVVDYPYPECTSSVLQALVLFKELCPGYRTEEIEECVRNASMFIENT
QRKDGSWLGTWGVCFTYGAFFSVQGLIAAGRTYENSSSIRKACDFILSKQLNTGGWGESHVSNET-VNIKGDRAHVVNTAWAMLTLIYAGQMERDPTPLH
CAAKELINMQLETGEFPQQEHVGCFNCSLFFNYPNYRNIFPIWALGEYCWHLR----
>tr|W5EPE2|W5EPE2_WHEAT Terpene cyclase/mutase family member OS=Triticum aestivum PE=3 SV=1
--------------------------------------------------------------------------------------------MITTSLRR
ALNQYSALQAHDGHWPGDLSGILFIMPMLIFSLYVTRSLNMVLSSEHQHEICRHIYNHQNEDGGWGTHIWGPSNMLGSCLNYAALRLLGETLDNDN-DVL
IKARAWILSHGSATAVPQWGKIFLSILGVYDWSGNNPIIPELWLLPHFLPIHPGRFWCFCRLVYMSMAYLYGKKFVGLITPTITALREELYNTPYSNIDW
GKVSNCCAEEDLHNPRSQVRNIVLVCLKKFVEPMLNWWPTNKLRGRALSKLMEQIHYNNETTEYITICPVDKALNMICCWVENPNSDAFKKHLPRVYDYL
WIAEDGMKAKIYDGCQNWETPFIVQAMCSTNLINEFGPTIKKAHDFMKKSQVLRNLPDYERFYRHRSKGSWTLSTIDNGWPISDGTAETLKTLLSLSNIS
ANLVGDPIEEERLYDAIDFLLSLMNKDGSICTYERRRTATWVELLNPSESFKNIVIDHPTSECTASVIDGMVLFKELYPQYRSEEVGNCIKNAVKYVEGK
QLKDGSWYGSWGICFTYGTMFAVKGLGAAGRNYYNSSSIRKACKFLLSKQQSTGGWGESYLSNYTEEYVDSGTPHTVETAWAMLGLIYGGQAEIDPVPLY
RAAQVLMSMQLETGEFPQQEHAGCANSAFYFNYPNYRNLFPIMALGEFRRRLVANK-
>tr|A0A0D3HKM5|A0A0D3HKM5_9ORYZ Uncharacterized protein OS=Oryza barthii PE=4 SV=1
ELHLKIGEG-NPLLRSPNGFLGRETWEFDPDAGTPEERAEVERLRRDFTRNRFTRREC--------------------------D-SSETEEVLLTALKR
VLDQHSSLQAQDGHWPGGFSGVLFILPLMIFALHVTHSLNDVLSRYIYNIQASHNFLIFNKDGGWSTLTLGPSTMFGSCVNYATLRLLGEELDGDD-NAL
SKGRAWILTHGTATAAPQWAKIFLSVYMIGLGTIQSFLNYGCFHIFYPFIQFVGPI-----------------------TPTILAMRDELYNVPYSKINW
NNARSSCCKDDIIYPPSWLQIVAMASLNSFVEPLFNLWPMNVLRQRALTNLMDHIHYEDENSYYIGLCPMNKVLNMIYCWIENPNSYAFRQHLPRIHDFL
WLAEDGMKSKVYGGCQCWETALIVQAYCSSGLTKEFAATPRKAHDFIKNS---QNCPSYSSFYRERSKGSWTLTNGENGWPIADTTAECLKAILLLSKIP
SNQVGDSIKEERSFDAVDCLLSFVNKDGTLSSAESKRTTPWVEFINPSESFRNIIVDYPY----------------------------------------
--------GSWAICFTYATFFAIKGLVAAGRTYQNSSSIRKACNFLLSKQLTTGGWGENYICCQV-EYVDSGRPHAVNTAWAMLGLIYAGHVEIDPIPLH
RAAMELINMQLDTGEFPQQEIVGSFNSSLFFNYPNYRNLFQIWALGEFRHRLLAKK-
>tr|K7UVI2|K7UVI2_MAIZE Uncharacterized protein OS=Zea mays GN=ZEAMMB73_686992 PE=4 SV=1
MWRLKVAEG-GPWLRSTNGFLGRAVWEFDPDLGTLDERSEIEKMRREFTQNRFTRRESSDLLMRMQCAKENGP----P---HINLQDEQTEEIILKSLRR
ALDKFSSLQASDGHWPGDFSGVMFIMPGL------------------------------NEDGGWGTLILGSSSMFGTCSNYVTLRLLGEELNGKN-NGL
AKGRTWILTHGGATLVPQWGKIWLSILGVYDWSGNNPIFPELWLSPQFLPFHPGKFWCLTRMVYLPMAYLYGKKFVGPITSTILAIREEIYDSSYEKIDW
SEARRTCAKEDLLCPRTPLQSAVWTSLYMYVEPVLSCWPMNKLRERALRSLMEHIHYEDVNTQYVCICAVNKILNMVCCWVEDPNSDAFKCHLARIPDFL
WLSEDGMKAQVYDGCQSWETAFIIQAFCATDLVNEYGPTIQRAHEFIKHSQVLRNHPGDQSYHRHTSKGSWTLSSVDNGWAVSDTTAEALKAVLLLSKIS
NNLVGYPLERGRLYDAVDCLLSFMNPDGTFSTYECKRTSSWIEILNPCESFPNMVVDHP-----------------------------------------
-------LGTWGVCFTYAAFFSMKGLVTAGRTYGNSMSIRKACQFLLSKQLNSGGWGESHLSNET-T--------------------PSYQIERDPAPLH
RAAKELINMQMETGEFPQQEHVGCFNKSLFFNYPNYRNIFPIWALGEYRRHLLAKK-
>tr|M8BIG3|M8BIG3_AEGTA Terpene cyclase/mutase family member OS=Aegilops tauschii GN=F775_12585 PE=3 SV=1
-------------------------------------------------------------------------EAI--LVTKLKN-YGETEDIILDALRR
VLITYSTLQAHDGHWPGGFSGILFIMPLMIFSLYVTGSLDMVISREHIREICRYIYNIQNEDGGWSTHILGPSSMFGSCVNYVTLRILGEELDG-N-EAL
YKGRAWILSHGSATASPQWAKIWLSVIGVYDWSGNNPVIPELWSVPHLLPIHPGKFWCFCRMVYMPMAYIYGKKFVGPITPTILALRDELYNKPYSEINW
NMARSSCAKEDLVYPPSRMQNIVLACLHKFVEPMLSWWPFNKLRKSALSSLMDHIHYEDENSNYVGLCPINKVLNMICCWIEDPNSYAFKRHLPRIHDFL
WISEDGMKAKVYVGCQSWETSLIAQAFCSTKLAKEFAPVLRKAHGFLKAAQVTQNFPTYNSYYRERSKGAWTLSNGENGWPIADTTAEAIKALLLLSKYS
PSLVGDPIEEQRLYDAVDCLLSYVEVIF------C------------------KYYPMIYVECTSSLVQALILFRNSYPEYRCEEIEECIKKGTLFIEKQ
QRTDGSW-GTWGVCFTYASFFATKGLVAAGRTYENSVTIRKACSFLLAKQLSSGGWGENYLGCET-DYVDSGSPHVVNSAWAMLALLYAGQVERDPTPMY
HAAKELINLQTETGEFPQQETVGNFNSSLYFNYSNYRNLFPIWALGEFHRRLVGNK-
>tr|A0A096R7Y1|A0A096R7Y1_MAIZE Terpene cyclase/mutase family member OS=Zea mays PE=3 SV=1
MWRLKIGEG-GPWMQTASDFHGRQVWEYDPVAGTDEERSKVEQLRRAFTENRFRRRESQDLLMRMQFAGQKYV--DLPAKIEEEDGEVPTEERLRESLRR
ALGCMAALQAEDGHWPGDYSGVMYLMPFWIFALHITGTVDAVLSKEHRREICRHIYNHQNEDGGWGLNVIDESAMFSTCLNYTSLRLLGEVQQE-ENDGL
AKGRAWILSHGTATAAPQWAKILLSVIGVYDWRGNNPVVPELWLVPRFLPIHPGRFWCFTRIMYMSIAFLYGKKFVGPITPTILALRDELYSSAYVHIDW
SKARNSCAKEDMRNKPSGIFKFISTCLNMFVEPVLNYWPLKKLRERALNHILEHIHYEDETTQYIGICSITKALNMICRWVENPNSDAAKRHNLRIHDYM
WIAEDGMKTKVCNGANNWELAFIIQALLSADTTNEYGPTVERAMGYIKRAQATTNPPGNPSYFRHKSKGSWPLSTVDYGWASSDTTAEVTKAMLLLSKVY
PNLVENSNGDEWMLNAVDCLLSFMNKDGSVSTFECQRTYSWLEILNPAESFRNIVADYPTVECTSSVLQALVLFGDFNSEYRSKEIKENVDKAAIFIESN
QNKDGSWYGTWGICFIYGTLHAINGLVAAGRNYENNICIRKACEFLLSIQLKTGGWAESYRSCERQ-------------------------MERDPTPLH
QAAKALISLQLESGDYPQQEHVGNTNCSVYFNYPNYRILFPVWALGEYHRKVRAK--
>tr|A0A0D9Y0Y5|A0A0D9Y0Y5_9ORYZ Uncharacterized protein OS=Leersia perrieri PE=4 SV=1
INHVEVAEG-MSTLWSTNGFLGRAVWEFDPNHGTPDDHAAVERARREFTDHRLGRRESADVLVRIQFAKQNKD--RIP-P--IKLGNEQTEEIAMASLRR
ALDEFSSLQADDGHWPGDMSGVMFIMPGL------------------------------NEDGGWATLMVSSSTMFGTCSNYITRRILGEEPS--N-EQL
TRGRQWIVSRGGATLVPQLGKIWLSILGVYEWSGSNPFFPELWLAPQFLPFHPGKFWGLTRMVYLPMAYLYGKKFVGPITPTILSLREEIYTAHYDGIDW
AQTRNACAKEDLLCPRTLLQNVVWSSMYKLVEPVASRWPMSKLRGRALDKLMEHIHYEDENTQYLCFCAISKALNMICCWVEDPYSDAFKRHLARVPDYL
WISEDGMKAQVYDGCQSWETAFIIQAFCATGLVNDYASTVARAHKFMKNSQVVRDHPGDQSYHRHRSKGSWTFSSADNGWAVSDTTAEALKAVLLLTKIA
SNVVGDPIERERLHDAVDCLLSFVNKDGSVSTFECRRASTWIEISRMH-----------------------------------------LLGASSFGVVQ
RTIPWLSLGTWGVCFTYGAFFSVKGLIAAGRTYGNSSSIRKACDFILSKQLNTGGWGESHISNET-VNIEGDRAHAVNTAWAMLTLIFAGQMERDPTPLH
RAAKELINMQLETGEFPQQEHVGCFNCSFFFNYPNYGNLFPIWALGEYCRHLRSKR-
>tr|A0A096RK80|A0A096RK80_MAIZE Terpene cyclase/mutase family member OS=Zea mays PE=3 SV=1
MWRLKIGEG-GPWMQTVSDFHGRQVWEYDPDAGTEEERSKVEQLRREFTENRFRRRESQDLLMRMQLTGQKHL--DDMAKIE--DG--ETEERLRESLRR
ALGWMSALQAEDGHWPGDFSGIMYIMPFWIFALHITGSIDVVLSKEHRREICRHIYNHQ-----------------------------------------
-------------------------VIGVYDWRGNNPVVPELWLVPRFLPIHPGRFWCFTRITYMSIAFLYGKKFIGPITPTILELREELYSLPYVQIDW
SKARNSCAKEDIRNKPSEIFKFISTCLNMFVEPVLNYWPLNKLRERALNHILEHIHYEDETTQYIGISPVTKALNMICCWVENPNSDALKRHIPRIHDYL
WIAEDGMNTKIYDGTHNWELALIIQAMLSADAANEYGPTIQRAMEYLKRAQVTTNPPGNPSYFRHRSKGSWPLSTIDNGWGSSDTSAEATKALLMFSKVY
PNLVENSNGDEWMLNAVDCLLSFMNKDGSVSTFECQRTYSWLEILNPLESFRNIVADYPTVECTSSVLQALVLFEEFNSEYRSKEIKENVKKAAIYIENN
QNKDGSWYGTWGICFVYGTLYAIKGLVAAGRNYENSICIRKACNFLLSIQLKTGGWAESYHSCERQVYVEGHSTHVVQTAWAMLALIYTGQMERDPTPLH
RAAKVLINMQLETGDYAQQEHVGSTNCSVYFNYPNYRILFPVWALGEYHRKVCTKS-
>tr|K3Z060|K3Z060_SETIT Uncharacterized protein OS=Setaria italica GN=Si019921m.g PE=4 SV=1
MWRLKVAEG-GPWLRSTNNFLGRAVWEFDPDGGTPEERAEVERLRREFTDHRFQRRSSADLLMRMQAARAAHR-RSLP-LPHIKLGDE-----------Q
ALDQFSSLQSSDGHWPGDFGGITTVVPTMIIALYVTRSLNAVISWRPMRHYQYITPSKFNEDSGWGTVIRGSSNMFGTCINYITLRLLGEEPNDKN-NAL
AKGRAWILSHGGAASLPQC---LSQILGVYDWSGCNPFFPELWLMPRFLPFYYIFGMFFQSVAYL-----YGKRFVGPITPTILALREEIYNTPYDKIDW
SEARCACAKEDLLTPRTRLQNVIWASLYKCVEPVMSSWPVNKLREKALKYLMEHVHYEDESSQYICLTAASKPLNMICCWVEDPNSDAFKRHLARIPDLL
WLSEDGMKGKGVDGCQSWETAFAIQAICATDLV-------------------TRNHPGDQTYHRHRSKGSWTFSTADNGWAVSDTTAEALE---------
-------------------------TNGSFSTYEPQRTSSWVEILGPCENFPNSVVDYPMH---WNILQALVLFKKLHPGYRTKEIENCIGNAARFIENR
QNEDGSWLGTWGVCFTYGICFSIKGLIAAGRTYENNSSIKNACQFLLSKQLSTGGWGESHESMIT-QNIQGDCANAVNTAWAMLALIYAGQFERDPTPLH
RAAKELINMQLETGEFPQQEHVGCFNCAVVFNYP---NVFPIWALGEYRRCIAKRD-
>tr|A0A087GUR7|A0A087GUR7_ARAAL Terpene cyclase/mutase family member OS=Arabis alpina GN=AALP_AA5G037300 PE=3 SV=1
MWRLKLSEG-----ESVNEHVGRQFWEYDSHFGTSHDRLHISHLRTNFTLNRFSSKHSSDLLYRFQCWKEKGR-ERLP-QVKVNGEEGENVEVLNVTLRR
SLRFYSTLQSEDGFWPGDYGGPLFLLPAL-----------------------------------------------------------------------
-------------------------VLGVYEWSGNNPLPPELWLLPYSLPFHPGRMWCHCRMVYLPMSYLYGKRFVCHINGTIMSLRRELYTIPYHHIDW
DTARNQCAKEDLYYPHPKIQDFMWSCLKKVGEPLLERWPFSKLRDRALQTVMQHIHYEDQSSHYICLGPVNKVLNMVCCWVDAPDSEAFKCHLSRIKDYL
WVAEDGMKMQGYNGSQLWDVTLAVQAILATNLVDEYGVMLKRAHNYIKNTQIRRNTCGDPGLYRHPSKGGWGFSTADNPWPVSDCTAEALKAALLLSQFP
VSLVGEAMPEEHLFDAVNFMLSLQNKNGGFATYELTRSYPWLEVINPSETFGDIIIDYQYVECTSAAIQGLELFTRTNSTYKRKEILKCIKKAVEFIEKT
QLPDGSWYGSWGVCFTYATWFGIKGLLAAGKTYETSVCIRKACDFLLSKQLSCGGWGESYLSCQN-TNLPGNKSHIVNTSWAVLALIEAGQDTRDPMPLH
RGAKSLINSQMEDGDYPQQEILGVFNRNCMISYSAYRNIFPIWALGEYHNLLLSLP-
>tr|A0A0D9XRK1|A0A0D9XRK1_9ORYZ Uncharacterized protein OS=Leersia perrieri PE=4 SV=1
MWKVKIGEG-NPLLRSPNGFLGREVWEFDPNAGTPEERAEVERLRHNFTSNRFTHRECGDLLIRMQERRHPLSWSW--PLHMLKQ-SSKTEEVLLSSLQC
VLNQYSNIQAEDGHWPGDYSGILFMLPLTIFALHVTGTLNDVLS-SEHIQRRWGLEYKY----------------FGPQLN-VWLMLLGEELENDN-DAL
SKGRAWILSHGSATSAPQWAKIYLSVIGVYDWSGNNPIIPELWILPHFLPFIQKIEKNGLSFIGRFWSYIYGKKFVGPITPTIVAIREELYNVPYDIIDW
NTARTSCYKDDIVYPPSWLQSVAMASANMFVEPVFNMWPMNKIRQRALSNIMDHIHYEDENTNYVGLCPINKVLNMICCWIESPKSLAVRQHLPRINDFL
WLAEDGMKSKVYTGCQSWECALAIQAYCSTGLTKEFSATLMKAHNFLKNAQVAKNCPSYRSFYRERSKGHGHYQMVKMAGS-------------------
IVVVKDSIKS----SRRSNERRKVNKDGTLSSADCKRTSSWVEFINPSESFQNIVVDYL-----------------------------------------
--------GSWAVCFTYATFFAIKGLVAAGRTYDRSCSIRRACNFLLSKQQSTGGWGENYISCHV--------------------------VEIDPAPLY
CAAKELINMQLEMGEFPQREVVSNFNSSLSFNYANYRNIFPIWALGEFCRRLLH---
>tr|Q0J778|Q0J778_ORYSJ Terpene cyclase/mutase family member OS=Oryza sativa subsp. japonica GN=Os08g0223900 PE=3 SV=2
MWKLKIAEG-GPWLKSGNSHVGRETWEFDPNFGTSEEREAVEAARIEFQKNRFRTRHTSDVLARMQLAKANNF-P------------INDTATVSDILKK
ALSYFSAIQAYDGHWPGDFPGPLFTTATMIIVLYVTESLTITLSSEHHKEICRYLYNRQNIDGGWGLHAEGESSMLSTALNYTALRLLGENVDDDI---M
HKARKWIHDHGGATMIPILGKVWLSVLGVFDWSGVNPIPPELFLLPSFVPIQPGRLWSHFRMAFIPMSYLYGKKFVGPITRLVISLREELHIHPYKKIDW
KEARKLCAKEDAYNPHMWLQECLSDCLYSFGEPFLTRWPISYMRKRALYQIAEFLKYEDENSQYICIGAAQKALSMLCCWIENPNSDAFKRHLARVADFL
WVGEDGMKVR-VCAGQLWDVAFAVQAILACSIAEEFGSTLKKAHGFIKTSQIMDNPSGDFSRYRHISKGGWAFQVADQGWQVSDCTAEALKALLLLSKCL
SDGADYQMETYCYFDAVNVLLSLQNPNGGYGAWELARTYPWMEIFNMTEIYADIIVEHQYVECTSSVIQALALFREKYPGHRKDEIDQCIRKATEFIEKL
QNDDGSWFGSWGICFTYGTWFAIEGLSAVGQCYDDSTCIRKACKFLLSKQLTNGGWGESHLSSRT-TNLDGEKSHIVNTAWAMLALMKAGQVERDPAPLH
KAARLIMSMQLSDGDFPQEEMIGSFLKNGPLCYMAYRNIFPIWALGEYQKLVFQNY-
>tr|K3YGC9|K3YGC9_SETIT Terpene cyclase/mutase family member OS=Setaria italica GN=Si013297m.g PE=3 SV=1
MWKLKIAEG-GPWIKSGNNNIGRETWEFDQNFGSNEEKEAVDSAREEFQKNRFQMRHSSDILARMQLAKENNF-GETP-V--------DNPNTVSEILRK
ALSYFSAIQAHDGHWPGDFPGPLFTTATMIIVLYVTESLGITLSSEHRKEIIRYLYNRQNVDGGWGLHAEGESSMLSTALNYTALRLLGQSVDDDM---M
PKARKWIHDHGGATMIPILGKVWLSVLGVFEWSGVNPIPPELFLLPSLVPVQPGRLWSHFRMAFIPISYLYGKKFVGPITRLVMSLREELHIHPYRKIDW
KKARKLCAKEDVYNPHTWLQECLSDCLYSFGEPFLTQWPISYMRKKALQQIAEFLKYEDENSQYICIGAAQKALSMLCCWIENHNSDAFKSHLARVADFL
WVGEDGMKVR-VCAGQLWDVAFAVQAILACNIAEEYINTLKKAHNFIKASQIMDNPSGDFSRYRHISKGGWAFQVADQGWQVSDCTAEALKALLLLSKFS
SDVAGDQIETGRLHDAVNILLSLQNPNGGYGTWELARTYPWMEIFNMTEIYADIMVEHQYVECTSSVIQALALFREKYPGHRKDEIDQCIRNATEFIEKL
QNDDGSWFGSWGICFTYGTWFAIEGLSAVGQSYGNSTGIRKACKFLLSKQLHNGGWGESHLSSRT-TNLDGEKSHIVNTAWAMLALMKAGQVERDPTPLH
KAAKLIMNMQLGNGDFPQEEMIGSFLKNGPLCYMAYRNIFPIWAIGEYQKLVLSVT-
>tr|W5I4V3|W5I4V3_WHEAT Terpene cyclase/mutase family member OS=Triticum aestivum PE=3 SV=1
MWKLKIAEG-GPWLTSGNNHFGRETWEFDRNAGSSEERDAVDAARAEFQKNRFRTRHSSDVLARMQLVKGNNF-E------T----SVDNIATVSETLKR
ALRYFSAIQAHDGHWPGDFPGPLFTTATMIVVLYVTESLGTTLSSEHRKEICRYLYNRQNMDGGWGLHAEGESSMLSSALNYAALRLLGEGADDDM---M
PKARKWIHDHGGATMIPILGKVWLSVLGVSEWSGVNPMPPELFLLPSFVPIQPGRLWSHFRMAFIPMSYLYGKKFVGPITKLVLSLREELHIHPYKKINW
KQARKLCAKEDAYHPHTWLQECLSDCLYSFGEPFLACWPVSHMRRKALRQIADFLKYEDDISRYICIGSAQKALSMLCCWSENPSSDAFKRHLARVSDFL
WLGEDGMKVR-VCAGQSWDVAFAVQAILACDVAQEFGTTLKKAHHFIKASQIVSNPTGDFSRYRHISKGGWAFQVADQGWQVSDCTAEALKALLLLSKFP
SEIVGDQMETCRFHDAVNILLSLQNPNGGYGTWELARTYPWMENLNMTEIYADIMVEHQYVECTSSVIQALALFRQKYPGHREDEVEQCIRRATEFIEKL
QNEDGSWFGSWGICFTYGTWFAIEGLSAVGQCYNNSTYIRKGCQFLLSKQLRNGGWGESHLSSTT-TNLDGEKSHVVNTAWAMLALMKAGQAERDPSPLH
EAARLIMSMQLGNGDFPQEEMIGSFLKNGPLCYMAYRNIFPIWALGEYHRLVLCSG-
>tr|C0P4Z6|C0P4Z6_MAIZE Terpene cyclase/mutase family member OS=Zea mays GN=LOC100382158 PE=2 SV=1
MWRLKIGEG-GPWLKSGNGHIGRETWEFDEDFGSEADREAVDSAREEFSKNRLRMRHSSDLLARMQIAKENGF-GRSP-L-L----VATGSSTVSETLRK
ALDYFAAIQAHDGHWPGDFPGPLFTTATMITVLYVTGSLDSTLSSEHRREICRYLHNRQNADGGWGLHAEGESSMLSTALNYTALRLLGEGGDGGPSSML
IRARKWIRDRGGATMIPILGKVWLSVLGVFEWSGVNPIPPELFLFPSWVPIQPGRLWSHFRMAFIPMSYLYGKKFVGPITRLVVSLREELHVHPYEKIDW
KAARNSCAKEDVYSPHTWLQECLSHCLYSFGEPFLTRWPISYMRKKALQQVAEFLKYEDENSQYICIGAAQKALSMLCCWIEKSNSDAFKRHLARVADFL
WIGEDGMKVR-VCAGQLWDVAFAVQAILACNIAEEYRGTLKKAHDFIKASQIMDNPSGDFSRYRHISKGGWGFQVADQGWQVSDCTAEALKVLLMLSRFS
SDIGSDQMETCRLYDAVNVLLSLQNPNGGYGTWELARTYPWIEIFNMTEIYADIMVEHQYVECTSSVMQALVLFREKDPWHRKDEIDQCIRGATEFIEKL
QNDDGSWFGSWGICFTYGTWFAIEGLSAVGQSYGNSTCIQKACKFLLAKQLKNGGWGESHLSSTT-TNLDKEKSHIVNTAWAMLALMKAGQAERDPTPLH
KAARLIMSMQLSNGDFPQEEMIGSFLKNGPLCYMAYRNIFPIWALGEYQKLVLQCD-
>tr|A0A0D3D5G0|A0A0D3D5G0_BRAOL Uncharacterized protein OS=Brassica oleracea var. oleracea PE=4 SV=1
MWKLKIG---SPWLRTTNNHVGRQTWEFDPLLGTPEELAAIEEARNSFTQNRFSNKHSSDLLMRLQFSGENLI---LP-QVKLEDIDDDTDKIVENSLKR
GLDFFSTLQAHDGHWPGDYAGPMFLLPGLIITLSITGALNTVLSEQHKHEMCRYLYNHQNEDGGWGLHIEGHSTMFMSVLNYVTLRLLGQGPDAGDG-AM
EKGRDWILNHGGATHITSWGKLWLSVLGAFEWSGNNPLPPEIWLLPYFLPIHPGRMWCHCRMVYLPMSYLYGKRFVGPITSTVLALRKELFSVPYEDIDW
NQARTLCAKEDLYYPHPLVQDILWASLHKVVEPVLSRWPGTILREKALRTTLEHIHYEDENTRYLCIGPVNKVLNMLCCWVEDPNSEAFKLHLPRIHDYL
WLAEDGMKM-GYNGSQLWDAGFAVQAILATNFVEEYGPVLKKAHSFVKNSQVLEDCPGDLSYYRHISKGAWPFSTADHGWPISDCTAEGLKATLLLSKVP
KEIVGEPLDTNRLYDAVNVLISLQNADGGVATYELTRSYPWLELINPSETFGDIVIDYPYVECTSAAIQALVAFRKLYPGHRKKDVDECIEKAVKFIESS
QATDGSWYGSWAVCFTYGAWFGVKGLEAVGKTLKNSPAVAKACEFLLSKQLPSGGWGESYLSCQD-TGIKGNKSHVVNTSWALLALIGAGQAEVDQEPLH
KAARYLIIAQLEEGDFPQQEIMGVFNRNCMITYAAYRNIFPIWALGEYRSKVILQQ-
>tr|B1PLH3|B1PLH3_SOLLC Terpene cyclase/mutase family member OS=Solanum lycopersicum GN=CAS1 PE=2 SV=1
MWKLKVA---SPWLRTTNNHVGREVWEFEADFGSPEDRAQIEKFREHFTKHRLEQKHSADLLMRYQLSKENQG---LP-QVKINDN-EVTEDNVATTLRR
ALSFYSTLQNNDGHWAGDYGGPMFLMPGMIIALSITGALNAVFSSEHKREMIRYLYNHQNSDGGWGLHIESHSTMFGSALSYVTLRLLGEGANDGDG-AM
EKGRKWILDHGSATAITSWGKMWLSVLGVFDWSGNNPLPPEIWLLPYILPIHPGRMWCHCRMVYLPMCYLYGKRFVGPITPTVLSLRKELFTVPYHEVDW
DKARNECAKEDLYYPHPLVQDIMWATLHKVVEPILMHWPGKRLREKALRTVMEHIHYEDENTRYICIGPVNKIINMLCCWVEDPNSEAFKLHLPRIHDYM
WVAEDGMKM-GYNGSQCWDTSFAVQAIIATGFGEEYGSTLRKAHSFLTNTQVLDNCPGDLDFYRHISKGAWPFSTADHGWPISDCTAEGLKAVLLLSKLP
SEMVGNPLEAKRLYDAVNVLLSLQNSGGGFATYELSRSYPWLELINPAETFGDIVIDYPYVECSSAAIQALTAFKKLYPGHRKEEVERCIAKAAAFIESI
QETDGSWYGSWAVCFTYGTWFGVLGLLAAGRNYNNSSSIRKACTFLLSKQVSSGGWGESYLSCQN-TNLEGNRSHVVNTAWAMLALIAAGQAERNPTPLH
SAAKELINAQQENGDYPQQEIMGVFNRNCMISYSAYRNIFPIWALGEYRAHVLKAN-
>tr|R0H2T0|R0H2T0_9BRAS Terpene cyclase/mutase family member OS=Capsella rubella GN=CARUB_v10016727mg PE=3 SV=1
MWRLKIGAKADPYLSTTNNYVGKQVWEFDPEAGSPEELAEVEHARKNFSANRSQYKASADLLWRMQFLREKNF---IP-RVIIEN-AEKTYEDANTALKR
GIHYMAALQSDDGHWPAENAGCMFFNAPFVICLYITGHLDKIFSLEHRKEMLRYLYIHQNEDGGWGIDVESHSFMFCTVINYICLRIFGVDPDHGKTSAC
ARARKWIIDHGGATGTPLFGKAWLSVLGVYDWSGCRPILPEFWFLPSYFPVNGGTLWIYLRDTFMAISYLFGKKFVATTTPLILQLREEIYPEVYNEIDW
SKARHCCAKEDLYYPQSFIQDLFWNSVHIFSEKIVNRWPFNKIRAKAVEKAMDLIHYHDEATKYVTGGAVPKAFHMLACWVEDPESDYFKKHLAQVPGYI
WIAEDGLKI--TFGSQLWDTPFMLQVMLAADVDEEIKSTLIKGYSFLKNSQFTEDPPGDFVKFRDRSKGGWGFSDKDQGWFVSDCTSESLECCLIFETMP
TEFIGEKMDVERLYEAVDMLLYMQSKNGGISIWEVESGKKWLEWLSPIEFIEDTILEHEYLECTGSAVVVLVRFLKQHPEYRQKEVQRFITKGVEYIESK
QTPDGSWFGNWGVCFIPGTFFAIRGLVAAGKTYENCEAIRRAVQFILRTQNVEGGWGESYLSCPK-IPLEG-KSNIVNTGQALIILILSGQMDRDPSPVH
RGAKVLINSQMDNGDFPQEDIRGVYKNNVLLHYPTYRNIYSLWALIYYSKALRLLH-
>tr|M4ETQ3|M4ETQ3_BRARP Terpene cyclase/mutase family member OS=Brassica rapa subsp. pekinensis GN=Bra032185 PE=3 SV=1
MWKLRIGAEADPYLFSTNNYLGRQIWEFDADAGSAEELAEVEEARRNFAANRSHYKASADLLWRMQFLREKKF---IP-RVVIDD-AEKAYEDAEKALRR
GILYMAALQADDGHWPAENSGCMFFIAPFVICLYITGHLDKIFSQEHRKEMLRYMYNHQNEDGGWGIHVESHSFMFSTVLNYICLRIFGEEADHGINSAC
AMARKWILDHGGATYTPLLGKAWLSVLGVYDWSGCKPIPPEFWLLPYYSPINGGTVWIYLRDVFMGLSYLYGKKFVATPTPLILQVREEIYDQPYKEICW
SQARNLCAKEDLYFPQSFAQDWFWNIVHMFSENIFNLWPFNKIRHKALQKTMEIIHYHDEATQYITGGAIPKPFHMLACWVEDPKSDYFKKHLARVPGFL
WIGEDGLKI--TFGSQIWDTAFLLQMMLAADVNDEIRSTLIKGYSYLRKSQITENPSGDFIKFRDISKGGWSFSDKDQGWPVSDCISESLKCCLIFESMP
SEFIGEKMDVERLYDAINILLYLQGNNGGIAIWEPAPGKTWLEWLNPVEFVEESTVEHESLECTGSAIVALLQFMKQFPDHRREEIEGFVTKGVKYIEDL
QMPNGSWYGNWGVCFIYGTFFAVRGLVAAGKTYHNCETIRRAVRFLIETQNIEGGWGESYLSCPR-TPLDG-KTNVVNTGQAMMALIMGGQMERDPLPVH
RAAKVLINSQLDNGDFPQQEMRGAYKMNLLLHYPTYRNMFTLWALTYYTKALRRT--
>tr|V4NWN3|V4NWN3_EUTSA Terpene cyclase/mutase family member OS=Eutrema salsugineum GN=EUTSA_v10017701mg PE=3 SV=1
MWRLRIGDKANPYLCTTNKFLGRQIWEFDVNAGSPEELAEVEEARKNFSENRSNYKASADLLWRMQFLREKKF---IP-RVIIED-AEKTYEDARTALRR
GILYMAALQADDGHWPAENAGCMFFNAPFVICLYITG---------------PLQENMP----------------------YSYENSYELEPDYGQQSAC
ARARKWILDHGGATYTPLFGKAWLSVLGVYEWSGCKPIPPEFWLLPSWFPISGGTLWIYLRDTFLALSYLYGKKFVATSTPLILQLREELYPQPYADIVW
SQARNQCAK-------------FWKSVHMFSENILNRWPFKKIREKAIRTAMELIHYHGEATQFITGGAVPKVFHMLACWVDDPESDYFKKHLARVPGFI
WIAEDGLKI--TFGSQIWDTAFLLQVMLAATFDDEIRSTLIKGYSYLRKSQLTENPPGVYTKFRDISKGGWSLSDKDQGWPVSDCIAESSECCLIFQDMP
SEFIGEKMEVERLYDAVNMLLYLQSDNGGIAIWEAARGKKWLEWLSPIEFIEDTIVEHEYLECTGSAIVVLARFMKQFPGHRTKEVKRFITKGVKYIEDL
QMPDGSWYGNWGVCFIYGTFFAVRGLVAAGKTYNNCEGVRKAVCFLLENQNIEGGWGESYLSCPN-TPLSG-TTNVVNTGQALMVLIMGGQMERDPLPVH
RAAKVLINSQMDNGDFPQQEVRGAYKMNVLLHYPTYRNMFTLWALTYYTQALRLLV-
>tr|A0A0D3DVY2|A0A0D3DVY2_BRAOL Uncharacterized protein OS=Brassica oleracea var. oleracea PE=4 SV=1
MWRLKIAAEAGPHLFSTNNYVGRQIWEFDANSGSPEEREEVDRARQNFSLNRSCFKASADLLWRMQFLREKKF---IP-QVIIEN-AEETYEDARAALRR
GVLYFAALQADDGHWPAENSGSMFFNAPFFISLYITGHLEKIFTPEHRKEFIRYLYNHQNDDGGWGIHVEGHSVMFCTVLNYICLRIFGMDQ----ESVC
ARARKWIIDHGGAAYTPLFGKIWLSVLGVYDWSGCKPMPPEFWMLPLSSPFNGGTVWIYLRDIFMAVSYLYGKKFVATPTPLIAQLREELYPQPYNKIKW
SQARNLCAKEDLYYPQSFLQDMFWKSVHVFSENLLNQWPLNKLRQRALRKTMEIIHYHDESTRYITGGCVQKPFHMLACWVDDPDGDYFKKHLARVSDFI
WIGEDGLKI--SFGSQLWDTALSLEVLLAADMDDEISSTLIKGYDFLKKSQLTENPPGDHRKFREITKGAWTFSDRDQGWAVSDCTAESLECCLIFESMP
--MLGEKMDAEKLYDAVNLLLYFQSKNGGLAVWEPARGNTWLEWLSPVEFAEDTVVELEYLECTGSAIVALVRFLEMFPGHRKEEVESFIRKGIKYIESF
QMPDGSWYGNWGVCFIFGTFNAVRGLVAAGKTYSNCDAIRRAVRFLLDTQNAEGGWGESYLSCPI-TPLEG-KTNVVNTAQAMMGLIMGGQMERDPSPVH
RAAKVLINSQLENGDFPQQEIMGVFKMNLLLHYPTYRNIFTLWALTYYTKALRLRM-
>tr|D7KVB4|D7KVB4_ARALL Terpene cyclase/mutase family member OS=Arabidopsis lyrata subsp. lyrata GN=ARALYDRAFT_316749 PE=3 SV=1
MWRLRIAAEAKNHLFTTNSYAGRQIWEFDAKAGSPEELAEVNKVRQKFSSNPPRFKSSADLLWRMQFLREKSF---IP-RVIIDD-EQKTYEDAKMALKR
GILYFAALQADDGHWPAENSGPLFFEAPFVISLYITGHLDKIFSQEHRKELMRYMYNHQNDDGGWGLHVEGHSVWFCTVINYICLRIFGIEPDQ--ENVC
ARARKWILDHGGATYTPLIGKIWLSVLGVYDWSGCKPIPPEFWMLPSSSPVNGGTLWIYFRDIFMAVSYLYGKKFVTKTTPLIAQLREELYPQRYSKIDW
SQARQQCAKEDLYYPQSFVQNLFWRGVHMLSENVLNQWPFNKIRQRALRKTMELIHYHNEVTRYITGGCVQNPFHMLACWIEDPESDYFKKHLTRVADYI
WIGEDGLKI--SFGSQLWDTALSLQVMLGAD-DESIKATLVKGYKFLENSQITQNPPGDHMKFRHITKGGWTFSDQDQGWPVSDCTAESLECCLIFESQP
FEIIGEKMDVKRLYDA--------SKNGGISAWEPALGKTWLEWLSPVEFMENTIVEHEYVECTGSVIIALARFKQQFPAHRTEEVERFIVKGVKYIENL
QMVDGSWYGNWGVCFMYGSFFAIRGLVAAGKTYSNCKAIRRAVQFFLNTQNVEGGWGESFLSCPN-IPLEG-KSNVVNTGQALMGLIMGGQMERNPLPVH
RAAKVLINLQMDNGDFPQEEIRGVFKMNVLLHYPTYRNMFTLWALTYYTQALRL---
>tr|V4P8R9|V4P8R9_EUTSA Terpene cyclase/mutase family member OS=Eutrema salsugineum GN=EUTSA_v10027177mg PE=3 SV=1
MWRLKIGAKADTHLFSTNNYVGRQIWEFDANAGSPEELAEVQEARRNFSDNRSRFKTSADLIWRMQFLREKKF---IP-RVKVED-AEKTYDDAKTALRR
GLLYFTALQAEDGHWPAENSGSIFFNAPFVICLYITGHLEKIFTLEHLTELLRYMYNHQNEDGGWGLHVESHSNMFCTVINYICLRILGVEASHDQGSAC
ARARKWILDHGAM-----------VVLGVYDWSGCKPIPPEFWLLPSSFPINGGTLWIYLRDIFMGLSYLYGKKFVATPTQLILELQEELYPEPYSQIDW
RQTRTRCGNEDLYYPRSFLQDLFWKGVHIFSEGMLNRWPFKNKRERALRTTIDLLHYHDEASRYITGGSVPKAFHMLACWVEDPEGDYFKKHLARVPDFI
WIGEDGLKI--SFGSQLWDTALSLHVLIDGDVDDEFRSTLHKGYDYLKKSQVTDNPPGDHIKFRHIAKGGWTFSDQDQGWSVSDCTAESLECCLFFESMP
FKFIDQKMDVDKLYDAVDLLLYKQSDNGGETAWQPADGKT-----CPVEFVEDAVVEHEYVECTGSAIVALAQFVKQHPEYRKEEVERFITKGVKYIEDL
QMVDGSWYGNWGVCFIYGTFFAIRGLVAAGKTYNNCEAIRRAVCFLLDKQNSEGGWGESYLSCPS-TPLGG-ITNVVNTGQALMVLIMGDQLERDPLPVH
RAAKVLINSQLDNGDFPQQ-------MNVMLHYPTYRNIYSLWALTLYTQALRRLL-
>tr|A0A078GJN1|A0A078GJN1_BRANA Terpene cyclase/mutase family member OS=Brassica napus GN=BnaA05g18920D PE=3 SV=1
MWRLRIGAAAEHHLFSTNNYVGRQTWEFDAEAGSPEELAGMEQARRNFSLNRSRFKTSGDLLWRMQFLSEKKF---IP-RVRVED-ADKTYEDAKTAMRR
GMLYLGALQAKDGHWPAENSGIMFLNSPFFICLYITGHLEEIFNVEHRKEFLRYMYIHQNVDGGWGIDIESDSCMLSTVLNYICLRILRVEPEQ--GSTC
AMARKWILDHGGATYTPLFGKVWLSVLGVYDWSGCKSIPPEFWMLPSFSPINGGTVWIYFRESFMALSYLYGKKFVAIPTPLILQLREELYLHPYAQIVW
SQAQNLCAEEDKYNQQSYLQDLFWKSVHMFSENILNRWPFNKIRERALQTTMKLIHYHDDSTRYLTTGCVPKVLCMLACWVEEPEGDYFKKHLARLHDFV
WIGDDGLKF-QICGSQIWDTAFSLQVLLAA--DEIIRSTLIKGYDFLKKSQVTENPPGDHLKFRHITKGGWNFPDKDQGLPDSDCTAESLECCLMFETMP
QEFIGEKMDVKRLYDAVNLILHFQSKNGGVTAWEPAPGKTWLEWFSPVEFMKDSVVEHEFVECTGSALVAIARFMKQFPEYKREQVKDFIKNGVKYLENL
QMSDGSWYGSWGVCFIYGTFFAVRGLVAAGKTYNDCEAIRRAVRFLLETQNEEGGWGESYLSCSK-IPLSGRKTNLVNTGQALISLILGGQMERDTRPVN
RAAKVLINSQLDNGDYPQEEMSGVLSVNLKLHYPMYRNIFTLWALTYYTQALRALQ-
>tr|R0H1N7|R0H1N7_9BRAS Terpene cyclase/mutase family member OS=Capsella rubella GN=CARUB_v10007073mg PE=3 SV=1
MWRLKIGAASPSHLFTTNNYVGRQIWEFDTDACSHEELSEVDEARRNFSLNRSRFKTSPDLLWRMQFMREKKF---IP-RVRVED-AEKTYEDAKAATRR
GILYLAALQADDGHWPAENSGVMFFNAPFLLCLYITGHLEKIFTMEHRKEFMRYLYNHQSEDGGWGLHIESHSCMLSTILNYICLRILGVEPDQ--GSAC
ARALKWILDHGGATYTPLFGKAWLSVLGVYDWSGCKAIPPEFWMLPSFSPINGGTVWIYFRESFMALSYLYGKKFVATQTSLILQLRKELYPQPYAQIVW
SQARNLCAKEDAFNQQSCIQDLFWRSVHILSENILSSWPFNKIRERALQTTIKLIHYHNEATRHLTGGCVSKVFCMLACWVEEPEGDHFKRHLARVLDFV
WIGDDGLKF--ISGSQLWDTAFSLKAILAG--DE-IRPTLKKGYDFLKKSQLTQNPLGDHHKFRNITKGAWSFSDKDQGLPISDCTAESLECCLMFETMP
LEFIGEKMDVKKLYDAVNMILHYQSKNGGLAAWEPAPGKTWLEWFSPVEFMENAIVEHQYVECTGSSIVAMARFMKQFPKHRRQEVEKFIKNGTKFIEDV
QMQDGSWYGNWAVCFLYGTLFALRGLVAAGKTYNNCEAIRRAVRFLLDTQNAEGGWGESYHSCLE-IPKDGNMTNVVNTGEALMSLILAGQMERDPRPVH
RAAKVLINLQLDNGDFPQEEMSGVFNVNLKFHSPNYRNIFTLWSLANYSQALLCLH-
>tr|A0A061G8U2|A0A061G8U2_THECC Terpene cyclase/mutase family member OS=Theobroma cacao GN=TCM_027374 PE=3 SV=1
MWRLTIGEGGNPYIYSTNNYLGRQTWEFDPNAGTPEERAEVEEVRQNYYNNRKHVRPSSDLLWQIQSLKEKNF---IP-PVKIKD-GEETCETATAALRR
GVHLLSALQASDGHWPAENSGPMFYFPPLAMALYITGHIDTVFSAEHRKEILRYIYCHQNEDGGWGLHIEGHSIMFSTALNYICMRLLGEGPDGGQDNAC
KRARKWILDRGGVTTIPSWGKTWLSILGLFDWSGCHPMPPEFWVLPSYFPIHPAKMWCYCRITYLPMSYLYGKKFVGPITPLILQLREELHIEPYHKINW
RQKRHLCAEEDLYYPHTVLQMLLWNSLSTFTEPLLSRWPLNKLREKALQKTMDHIHYEDECSRYITIGGVEKPLCMLACWLENPTGDYFKKHLARIADYL
WVGEDGMKM--SFGSQVWDSSFALQALLASDLTNDIRPTLMKGHDFLKHSQVKDNPPGDFKRFRHISKGSWTFSDQDHGWQVSDCTAESLKCCLYFSKMP
PETVGEKMEPEKFYDAVNVIISLQSQNGGFSGWEPATAGLWMEWLNPVEFLDDNVIEHEYTECTASAIQALVLFTESYPGHRGKETEKCIAKAVLFLENV
QKPDGSWYGSWGICFTYGTWFALGGLAAAGKNYNNCLAVRKGLDFLLETQTDDGGWGESYLSCPK-TPLEGNRSNLVHTAMALMGLIHGGQAKRDPNPLH
RAAKLLINSQLPDGDFPQQEMMGVFMSNCMLHYASYRNTFPTWALAEYRKHVPLPS-
>tr|A0A087HJH0|A0A087HJH0_ARAAL Terpene cyclase/mutase family member OS=Arabis alpina GN=AALP_AA2G234400 PE=3 SV=1
MWKLKIGERNDPYLFSTNNFAGRQTWEFDPHGGSPEEQQAVVEARRSFYENRFRVKASSDLLWRMQFLKEKKF---IP-PVKVESSDKITFESATNSLRR
GVHFFSALQASDGHWPAENAGPLFFLPPLVFCLYITGHLDDIFTLEHRKEILRYIYCHQKEDGGWGFHIEGHSTMFCTALNYICMRILGESPDGGEENAC
ARARKWIHVHGGVTCIPSWGKTWLSILGVFDWSGSNPMPPEFWILPSFFPVNPAKMWCYCRMVYLPMSYLYGKRFVGPITPLILQLRKELYLQPYGEINW
KKIHHLCAKEDAYYPRPLVQELIWDSLYIFTEPFLTRWPLNKLRQRALQVAMKHIHYEDENSRYITIGCVEKVLCMLACWVEDPNGDYFKKHLARIPDYL
WVAEDGMKM--SFGSQLWDTGFAMQALLASNLSSEISDVLRRGHEFIKKSQVRENPSGDFKSYRHISKGAWTFSDRDHGWQVSDCTAHGLKCCLLLSMMA
PNIVGPKTDPERLYDSVNLLLTLQSKKGGMTAWEPAGAPEWLELLNPTEMFSDIVIEHEYTECTSSAIQALSLFKQLFPDHRKAEINKFIEKAVQYLENM
QTPDGSWYGNWGICFMYGTWFGLAGLAAAGKTYNDCVAIRKGVQFLLATQKDNGGWGE-SYSCSE-IAEEADITNVVQTSWALMGLIHSGQAKRDPVPLH
RAVKLIINSQLENGDFPQQQSTGVFMKNCTLHYAAYRNIHPLWALAEYRARVPLP--
>tr|V4TDJ4|V4TDJ4_9ROSI Terpene cyclase/mutase family member OS=Citrus clementina GN=CICLE_v10030771mg PE=3 SV=1
MWRLKIGDHGDPYIFSTNNFDGRQFWVFDPDAGSPEEIAEVEEARLNYFKNRFNVKNASELIWQIQILREKKF---IP-QVKIGDHGEKTHEIATTALRR
AVHKFSALQSSHGHWPADNSGPLFYNTPFIICLYITGYLNIVFSSEHRKEMLRYTYNHQNEDGGWGLHVEGHSTMFGTVFNYICMRLLGEGPDGGGNNAC
ARARKWILDRGGATGIPSWGKTWLSILGVYDWSGCNPMPPEFWKFPSFLPISPGKLLCYCRVTYMPMSYLYGKRFVSPITPLILQLREEIYTQPYSDIHW
SKMRHFCAKEDIFFPHTSVQNLLWDTLYNVVEPVLNRWPLNQLREKSLEIAMNHIHYEDEASRYMTIGCVEKPLNMLSCWVEDPNSDYFKKHLSRISEYL
WVGEDGMKV--SFGSQTWDCAIAVQTLLACSLTDEIGPILMKAHDFLKTSQVTDNPPGDFKRFRHISKGGWTFSNKDHGWPVSDCTAEALLCCLHFSMMR
PEIVGEKMEPERFYDAVNYVLSLQSETGGVPAWEPTGAPSWLELLNPIEFLDEVIIEYDKVECTASALKAMTLFKKLYPKHRTKEVKNFIAKATKFIEDI
QKSDGSWYGSWGICFTYGAWFAISGLVAAKKTYSNCLAIRKATDFLLKIQCEDGGWGESYRSCPN-IPLDGNRSNLVQTAWAMMSLIHAGQMERDPTPLH
RAAKLLINSQLEDGDFPQQELTGVFMENCMLHYPIYRNIFPMWALAEYRSRLLLPE-
>tr|U5GSS9|U5GSS9_POPTR Terpene cyclase/mutase family member OS=Populus trichocarpa GN=POPTR_0001s14610g PE=3 SV=1
MWRLKIAEGGDPHIYSTNNFLGRQTWEFDPDAGTLEERAEVEEARQNFWRNRNEVKPSSDLLWKFQFLRGKKF---IP-QVKIED-GEESYEKATSALRR
SVHLFSALQASDGHWCAENSGPMFYFPPLVFSLYITGHLNAIFSAEHKKEILRYIYCHQNEDGGWGLHIEGHSTMFCTVLNYICMRMLGEGRDGGKDKAC
ERARKWILDHGSAIAISSWGKTWLAILGMYEWAGCNPMPPEFWFLPSTSPIHPGNLLGYCRLTYLPMAYLYGKRFIGPITPLILQIREEIYNEPYEKLNW
RRVRHLCAKEDNYYPHTSIQILFWDAIYTFGEPLLTRWPFNKLREKALDITMDHIHYEDESSRYITIGCIEKPLDMLACWVEDPNGDYFRRHLARIKDYL
WLGEDGIKM--SFGSQVWDTSLALQALIASNLSEETGPALKEGHSFIKNSQVTENPPGDFRRFRHISKGSWTFSDKDHGWQVSDCTAESMKCCLLFSTMP
PEIVGEKMEPQKLFDSVNILLSLQSKNGGVSAWEPAGSGLWLEWLNPVEFLEDLVVEHEYVECTSSTIQALVLFKKLYPGHRTKEIQNSIINGVKFIEEL
QKPDGSWYGNWGICFIYGTWFALGGLAAAGKTYSNCLAVRKGVDFLLGSQRDDGGWGESYLSCPK-VPLEGNHSNLVQTAMAMMGLIHGGQADRDPAPLH
RAAKLLINSQTELGDFPQQVIDLFLCTQREEIMRKERER----ERDRRRREAACRL-
>tr|A0A0D2UH65|A0A0D2UH65_GOSRA Gossypium raimondii chromosome 10, whole genome shotgun sequence (Fragment) OS=Gossypium raimondii GN=B456_010G223200 PE=4 SV=1
MWRLKIGEGGDPYLYSTNNFLGRQTWEFDPSAGTAEERAEVEEARLNFYNNRYNVQPSSDLLWQMQFLREKKT---IP-QPKIED-GEETYEVTTAAVKR
SVHLFSALQSRHGHWPAENSGPMYYIPPLVMSLYITGHLNTIFSREHRKEILRYIYCHQNEDGGWGLSIGVHSTMFCTTLNYICMRLLGVGPDGGLNNAC
ERARKWILDRGAVTTISSWGKTWLSILGVYEWSGCHPMPPEFWLFPSYFPINPAKMLCYCRLTYLPMSYLYGRKFVGPITPLILQLRQELHTEPYDEIDW
SKKRHLCAKEDLHYPHTLLQILLWDSLYLFSEPLLNRWPFNKLRKKALKVAMDLIHYEDENSRYITIGCVEKPLCMLACWVEDPNGIYFKKHLARVVDCL
WVGEDGMKL--GVASQSWDASLLLQALLATNLYDEIGPTLMKGHNFLKNSQVRDNPPGDFKRFRHISKGSWTFADQDHGWQVSDCTAESLKCCVNFAMMA
PEMVGEKMEEEQFYDAVNVLLSLQSKNGGYPAWEPAGGAFWWEWLNPIEFLEDLTKEYEHVECTSSSIQALAIFKKLYPGHRKIEIENCIRKAAKFIEDV
QYPDGSWYGSWGICFFYGTWFALSGLKAAGKNFKNCLAIRKGVEFLLKTQREDGGWGESYLSCPT-TPIEGKESNLVNTAQALMGLIIGGQAERDPTPLH
RAAKLLINSQLPNGDFPQQGLTAVFMRNCMLHFALYRSIFPLWALAEYRNHVWPSK-
>tr|A0A0D2VDX3|A0A0D2VDX3_GOSRA Gossypium raimondii chromosome 10, whole genome shotgun sequence OS=Gossypium raimondii GN=B456_010G223600 PE=4 SV=1
MWRLKIGEGGDPYLHSTNNFLGRQTWKFDPNAGTDEERAEVEEARLNFYKNRFNVQPSSDLLWQLQFLREKKM---IP-QPKIED-GEETYEATTAAVKR
SVHLFSALQSIHGHWPAENAGPMFYFPPLVMSLYITGHLNTIFSAEHRKEILRYIYCHQNEDGGWGLYIGGHSTMFCTALNYICMRLLGVGPDGGLNNAC
ERGRKWILDRGGVTTISSWGKTWLSILGVYEWSGCHPMPPEFWLFPSYFPVHPAKMFCYCRLTYMPMSYLYGRKFVGPITPLISQLREELHIEPYNEIDW
STKRHLCAKEDLHYPHTWLQILLWDSLYIFSEPLLNCWPFNKLREKALKVTMDLIHYEDESSQYITVGCVEKPLCMLACWVEDPNGIPFKKHLSRVDDYV
WVGEDGIKM--SFGSQVWDASLVLQALLASNLSNEIGPTLMKGHNFLKNSQVRDDPPGDFKKFRHISKGSWTFSDRDHGWQVSDCTAESLKCCLSFSMMA
PEMVGEKMEREHVYDAVNVLLSLQSKNGGFSAWEPAGGGFWWEWLNPVEFLEDLVKEYEYVECTSSSIQALVLFKKLYPGHREQEIENCIRKAAKYIEDI
RYPDGSWYGNWGICFFYGTWFALLGLKAAGKNFENCLAIRKGVDFLLRTQREDGGWGESYLSCPK-TPIEEKESNLVSTAQAMMSLIVSGQAERDPTPLH
RAAKLLINSQLPNGGFPQQGLAGVFMRNCMLHYAIYRNVFPLWALAEYRNHVWPSK-
>tr|B9SWS3|B9SWS3_RICCO Terpene cyclase/mutase family member OS=Ricinus communis GN=RCOM_0010700 PE=3 SV=1
MWRLKIAEGGDPHIYSTNNFLGRQIWEFDPDAGAPEERAQVEEARQHFWNNRFQVKPSSDLLWQFQILKEKNF---IT-KVKIED-GKETSEDARNALRR
SVHLMSALQASDGHWCAENAGPMFYLPPLVFSLYITNHLNIVFSAEHRKEILRYIYCHQNEDGGWGLHIEGHSSMFCTVLNYICMRILGEGPNGGKDNAC
ERGRKWILDHGSATAISSWGKTWLSILGLYEWEGCNPMPPEFWVCPTIFPMHPAKMFCYCRLTYMPMSYLYGKRFVGPITPLILQLREEIYNESYNKIKW
KTLRHLCAKEDNYYPHTLVQILMWDALYMFSEPLFTRWPFNKLRKKALKLTMDHIHYEDENSRYITIGCIEKSLCMLACWDEDPNGEAFKKHLARVPDYI
WVGEDGIKM--SFGSQLWDTSFALQALIASNLSDEIGPTLKEGHNFIKNSQVTENPTGDFKSFRHISKGSWTFSDKDQGWQVSDCTAEGLKCCLLFSMMP
SNIVGEKMEPEKLFDAVNIIL----KHGGSSAWEPVEARLWLEWLNPVEFLEGLIIEYEYVECTSASIQALVLFKELYPGHRTKDIENFIQNATRSLEDE
QKPDGSWYGKWGICFIYATWLALKGLAVAGKTYENCLAIRRGVDFLLKLQTNDGGWGESYLSCPK-VPLEDNRSNLVHTAMAMMGLIHGGQAKRDPTPLY
RAAKLLINSQTELGDFPQQEQIGVFMRNCMLHYAAYRNIFPLWALAEYCQHVSLPS-
>tr|Q401R5|Q401R5_EUPTI Terpene cyclase/mutase family member OS=Euphorbia tirucalli GN=EtOSC PE=2 SV=1
MWRLKIAEQGNPNIYSTNNFLGRQIWEYDANAGTPQDIAEVEDARLRFWNNRFHIKPSSDLLWQFQFLREKKF---IP-AVRIKE-DEETYEAATAALRR
GVHLFSALQAKDGHWPAENAGPMFFVPPMVFCLYITSQLDNVLSKEHIIEILRYIYCHQNEDGGWGLHIEGHSMMFSTVLNYICMRILGEGPNGGLENAC
ERARKWILDHGSATAISSWGKTWLSILGVYEWEGSHPMPPEFWFLPTMFPIHPAKMFCYCRMTYMPMSYLYGKKFVGPLTPLILQLRQEIYNQPYHTINW
KSIRHLCAKEDNYYPRTWIQKLMWDSLYIFTEPILRRWPFNKLREKALKKTMDHIHYEDENSRYIVIGSVEKPLNMLACWVGDPNGDAFKKHLARIVDYI
WVGEDGLKV--SFGSQVWDASFGLQALIASNLSDEIGPILNHGHNFLKNSQVTENPYGDHKSFRHISKGAWTFSDKDHGWQVSDCTAESLKCCLLFSLMP
SEIVGEKLEAGKLYDAVNILLSLQSENGGLSGWEPARGSPWLEWLNPVEFLEDLVVEHEYVECTSSSIQALTLFKKLYPGHRTKEIENFIAKAVKFIEEI
QKPDGSWYGNWGICFIYGTWFGLGGLAAAGNSYENCIAIRRGVEFLLNSQRVDGGWAESYLSCPN-VGVDGDRSNLVQTAFAVLGLIHGGQAKTDPTPLH
RGVKFLINSQTQLGDFPQQELTGAFMRNCMLHYALYRNIFPLWALAEYRRNVPLSP-
>tr|A0A0D3CAT8|A0A0D3CAT8_BRAOL Uncharacterized protein (Fragment) OS=Brassica oleracea var. oleracea PE=4 SV=1
MWRLKIGEGRDPYLKSTNSFAGRQIWEFDPHAGTSEERAAVEETRRSFHDSRHQVKACSDLLWRMQFLKEKKF---IP-PVKVDDAERITKEAATNALRR
SVDYFSALQSSDGHWPAEITGPLFYVPVMVFCFYITGHLDEIFTKEHRKEMLRYIYCHQNEDGGWGLHIEGKSGMFCTALNYICLRILGEGPDGGPRNAC
KRARQWILDRGGVAYIPSWGKSWLSILGIYDWNGTNPMPPEIWLLPSWLPIHLGKTTCFCRLVYLVTSYFYGKRFVGPITPLILELREELYLQSYEEINW
NRARSLYAKEDMYYPHPSIQDLVWDSLHVFGEPLLTRWPLNKVREKALRVAMEYIHYEDENSRYINIGCAGKAMCVLACWVEDPNGEYFKKHLARVPDYF
WIAEDGMKV--SFGSQLWDTSLAIQALLASNLSDETADVLKKGHDFIKRSQIRENPSGDFKKNRHISKGGWTFSDRDQGWNVSDCSAEAFKCCLLLSKMP
PDVVGPKMEPEQLYDSVNLLLSYQSENGGMTAWEPARGYGWLELFNPTEMLADLVIEREYVECTSSVIQALIMFKKLYPDHRTREIDRTIEKAVQFIENT
QEADGSWYGSWGVCYTYATWFALEGLASVGKTYENCLAMREGVGFLLKKQNSSGGWGESYLSCSE-IELEGGRSNLVQTAWALMGLIKTGQAERDPLPLH
RAAKLIINSQLENGDYPQQEMTGVFMKNCFLNYVTYRNIFPIWALAEYRKVF-----
>tr|L7WI23|L7WI23_AZAIN Terpene cyclase/mutase family member OS=Azadirachta indica GN=BAMYR PE=2 SV=1
MWKLKIAEGDSPYISTTNNFVGRQIWEFDPNAGTAEELAEVEEARQNFYKNRHQVKPASDLIFRLQFLREKNF---IP-QVKVED-GEETYDTATAAMKR
AAHYFSAIQASDGHWPAENSGPMYFLPPFVFCLYITGHLDTVFTAAHRREVLRYLYNHQHEDGGWGIHIEAPSSMFGTVYSYLTMRLLGLGPNDGENNAC
ARARKWIRDNGGVTYIPSWGKNWLSILGLFEWAGTHPMPPEFWMLPSHFPLHPAQMWCFCRLVYMPLCYLYGKRFVGPITPLIKQLREELHTEPYDKINW
RKVRHQCAKTDLYYPHPFVQEVLWDTLYFATEPLLTRWPLNKVREKALKQTMKIIHYEDQSSRYITIGCVEKPLCMLACWVEDPEGVAFKKHLERIADFI
WIGEDGMKV--TFGSQTWDTALGLQALLACNIVDEIGPALAKGHDYLKKAQVRDNPVGDYTSFRHFSKGAWTFSDQDHGWQVSDCTAESLKCCLHFSMLP
PEIVGEKHDPERLYEAVNFILSLQDKNGGIAVWEKAGASLMLEWLNPVEFLEDLIVEHTYVECTASAIEAFVMFKKLYPHHRKKEIENFLVKAVQYIENE
QTADGSWYGNWGVCFLYGTCFALGGLHAAGKTYNNCLAIRRAVEFLLQAQSDDGGWGESYKSCPS-VPLDGKRSTVVHTALAIFGLIHAGQVERDPTSIH
RGVKLLINSQLENGDFPQQEIMGVFMRNCMLHYAQYRNIFPLWALAECRRKVPLPN-
>tr|C1K2M2|C1K2M2_9GENT Terpene cyclase/mutase family member OS=Gentiana straminea GN=AS1 PE=2 SV=1
MWRLKIGEGGDPNLYSTNNYVGRQIWEYDRNAGIAEEREEVEEARRNFWNNRRHVKPSSDILWRLQFLREKNF---IP-AVKVDDGQEINHQMATTALRR
AVHLLSALQSSDGHWPAENAGSLFFLPPLIICLYITGHLNNIFPTEHTHEILRYLYCHQNEDGGWGLHIEGHSTMFCTALNYICMRILGEGPDGGKENAC
ARARKWILDHGSVTAIPSLGKAWLSILGLYDWSGTNPMPPEIWSLPSSLSIHPGKMGCYCRMVYMPMSYLYGKRFVCRITPLISELREELHCEPYNQIRW
KRYRHVCAKEDLYYPHPLIQDLIWDFFYICTEPLFTHWPVNK-RAKALDATMKHIHYEDENSRYITVGSVEKVLCMLACWVEDPNGDYFQKHLARIPDYI
WVAEDGMKM--SFGSQLWDICFAIQALLASDMTEEITDTLRKGHDFIKNSQVKENPSGDFKSYRHMSKGSWTFSDQDHGWQVSDCTAEGLKCCLLLSTMP
QEIVGERIELERIYDAVNILLSLQSKNGGLPGWEPVRASDWLELLNPTDSFADLVIEHEHAECTASAIDALVLFKKLYPNHMTKEIESFITNASNYLEDV
QMPDGSWYGNWGVCFIYGTWFALRGLAASGKTYNNCQVVRKAVNFLLTTQQKDGGWGESY-SCPE-IPLEGNRSNLVHTAWAMMGLIHSGQAKRDPTPLH
CAAKLLINSQLENGDFPQQEIAGVFFKNGMLHFASYRSIYPLWALAEYRKQVP----
>tr|M5WR68|M5WR68_PRUPE Terpene cyclase/mutase family member OS=Prunus persica GN=PRUPE_ppa001797mg PE=3 SV=1
MWKLKFGAEGDPYLFSTNEFVGRQTWEFDPHAGTPQERAEVEEARQNFYNNRYKVKASSEILWRMQLHRERNF---IP-QVKIEDDDEERHEKATAALKR
AVAYWSALQSPHGHWPAETTGPLFYTPPVVMALYITGHLNMVFSADHRKEMLWYMYCHQNEDGGWGLHMEDHSMMFCTLLNYICMRLLGEGPDGGLDNAC
ARARKWILDHGGATHSSSWGKIWMAILGVYDWEGNNPIPPELWSCPSFLPFHPAKILCYTRMAYLPMSHLYGKRFVGRITPLILQLREEIYNEPYNEIKW
SKVRHLCAKEDNCHPHGKLQSLMWDSLHTICEPLFTRWPFKKFREKALQETSKHIHYEDENTRYITIGVVIKPLNMLACWAEDPNGESYKKHLARIADFI
WVAEDGMKM--SFGSQMWDASFAIQALLAANLNDELGSVLKKGHDFLKKSQVRDNPSGDFLAFRHISKGGWTFSDQDHGWQVSDCTAEALKSCLLLSMLP
PQLVGEQLEPERLYDAVNVILSLQSPNGGVSAWEPAGAPKWLEWLNPIEFLGDLVIEYEHVECTSSSIRALALFRKLYPAHRKKQIDNFITTAAGYIEDI
QNPDGSWYGNWGICFIYGTWFAIRGLEAAGKTYNNCAAIRRGVEFLLKTQRDDGGWGESYISCTN-TPLEGDRSNLVQTAMGLMGLIHGGQAERDPTPIH
QAAKLLINSQLENGDFPQQEVMGVFMRNAMLNYAAYRNSIPIWALAEYCHMVPKPL-
>tr|A0A067KL72|A0A067KL72_JATCU Terpene cyclase/mutase family member OS=Jatropha curcas GN=JCGZ_06062 PE=3 SV=1
MWRLRVAEGGDPYIYSTNNFLGRQIWEFDSDAGNPEEREGVEKSRQNYWNNRFQIKPSSDLLWQFQFLREKKF---IP-QVKLQD-GEETYENATAALRR
SVHLFSALQASDGHWPAENSGPLFYFPPLVFSLYVTGHLNTVFSAEHRKEILRYIYCHQNEDGGWGLHIEGHSSMFCTVLNYICMRILGNGRDGGKDNAC
ERGRKWILDHGGATAISSWGKTWLSILGMYEWDGSNPMPPEFWACPIIVPLHPAKMMCYCRLTY-------VPMSYLYGKRFVGPITSLILQIREEIYNE
PYNKINWKNEDNYYPHPMIQKLLWDALYIFSEPLFTIWPFNKLREKALKITMDHIHYEDENSRYITIGCVEKPLNMLACWVEDPNGDAFKKHLARILDYI
WVGEDGIKM--SFGSQVWDTSLALQALMASNLCDEIGPTLKEGHNFIKNSQVTENPSGDFKRFRHTSKGAWTFSDKDHGWQVSDTTAEGLKCCLLFSMMP
SEIVGEKMDAIKLYDSVNVLLSLQSENGGFSAWEPAGERLWLEWLNPVEFIEDLVIEHDYVECTSSSIQALVLFSTLYPEQRNREINNSIVNAVRFIEDI
QKPDGSWYGNWGICFMYGTWFALKGLAAAGRTYENCPAIQKGVDFLLKSQRDDGGWAESYLSCPK-VPYEGDRSNLVQTAWAMMGLIHGGQVKRDPMPLH
RAAKLLINSQTELGDFPQQGQSGVFMRNCMLHYALYRNTFPIWALAEYRLHVLLPS-
>tr|R0IR41|R0IR41_9BRAS Terpene cyclase/mutase family member OS=Capsella rubella GN=CARUB_v10008384mg PE=3 SV=1
MWKLKIGEGNDPYLMSTNSFAGRQIWEFDPNAGTSEERVAVDEVRQSFYDNRHRVRASSDLLWRMQFLKEKSF---IP-AVKVEDAETLTKEAATIALGR
SVHYFSALQSSDGHWPAEIAGPLFYVPMMVFSFYITGHVEVIFSAEHRKEMLRYIFCFQNEDGGWGFHIEGKSCMFCTALNYICLRILGQDSDAGP---C
KLARKWILDRGGVTYIPSWGKSWLSILGVYDWSGTNPMPPEMWLLPSFLPIHLGKTTSLCRIIYLLMSYFYGKRFVGPITPLILKLREELYLQAYEDINW
NTARRLCAKEDMYYPHPPIQDLVWNSLHIFMEPVLTRWPFNKVREKALEVVMEYIHYEDENSRYINTGCVGKAMSMLACWNENPNGEYFKKHLARIPDFL
WIAEDGMKL--SFGSQLWDTTLTVQAFLACNLSNEIANALMKAHGFIKKSQIRENPSGNFNKHRHISKGGWAFSDRDQGWQVSDCSAEALKCCLLLSMMP
PDVVGPKMDTVNLYDAVNFILSYQSKNGGMSAWEPVRGYGWLELFNPTEILADVVVEHEYVECTSSVIQALVMFKKLYPDHRTREIDMTIEKGLQFIESR
QEADGSWYGSWGVCYTYATWFALEGLAVAGKTYDNCLAMREGVRFLLMKQNNNGGWGESYQSCSE-VALEGGRSNIVQTAWAMMGLIHTGQAERDPVPLH
RAAKLVINSQLENGDYPQQEMTGVFMKNCFLNYVTYRNIFPIWALAKYLKVVNVVN-
>tr|A0A059CJA8|A0A059CJA8_EUCGR Terpene cyclase/mutase family member OS=Eucalyptus grandis GN=EUGRSUZ_D02459 PE=3 SV=1
MWRLKIAEGGSPYIYSTNDYAGRQIWEFDPDAGTLEERAEVEEARRHFYNNRFKVKPSGDLLWRMQFLREKNF---IP-PVKVAE-EEETHEKASATLRR
SVNFFSALQASDGHWPAENSGVLFFHPPLVICLFITGHLNIVFSSEHRKEMLRYMYNHQNEDGGWGLHVEGHSTMLSTVLNYICMRIFGEGPDGGEDHAC
ARGRKWILDRGGATHISFYGKIWLSILGLYDWSGTKPVPPELLLLPSFLPLHPAKLWCYFRTLYMPASYLYGRRYVAPITPLVQQLREELLTQPYCNISW
TKARHLCAKEDLYRSRPSVVNLLWDGFYLLSEPFLNNWPLNK-----------------------------WALSMLACWVEDPNGEYFKKHLARIQDFI
WVAEDGMKI--SFGSQLWDTSLGIQALLASNLTSEIGPILRKGQDFIRRSQVNDNPSGDFQSYRHFSKGSWTFSDQDQGWQLSDCTAEGLTCCLLFSQMP
PEIVGEKVEPKRLYDAVNIILSLQSKNGGLTAWEPATAANWLELLNPLEFLDEVIVDREYVECTSAAIKALVLFKKLCPRHRSEEIQDFISNAVRYLESA
QMQDGSWYGQWGVCFTYSTWFALKALAAAGKSYKNCTAIRKGVAFLLQIQFQDGGWGESYLSCPR-VSLEGNRSNLVQTSWAMMGLIHAGQAERDPAPLH
RAAKLIINSQMENGDFPQQEITGAFKKNCMLHYANYRNIFPIWALAEYCNLVLLNS-
>tr|A0A059DHQ8|A0A059DHQ8_EUCGR Terpene cyclase/mutase family member OS=Eucalyptus grandis GN=EUGRSUZ_A02035 PE=3 SV=1
MWKLKIGEGADPYLFSLNNFVGRQIWEFDPEAGTPEERAEVEAARQNFYNNRFKVRPSSDLFWRFQFLREKNF---IP-PVKIED-GEDTYEKATAAVKR
CVSFWSALQSSHGHWPAENAGPIFYFPPLVMSLYVTGHLNNVFHAEHRREILRYIYYHQNEDGGWGLHIEGHSTMIGTVLNYVCMRLLGEGPDGGLDNAC
ERGRKWILDHGSATKTASWGKTWLAIIGCYEWTGTHPMPPEFWDFPSFMSPAQMFCYCRLTYMPMS--YLYGKKFVGPITPLIKQIREEIYYEPYDQISW
WRVRHSCAEEDAHYPHTRLQTLMWDTLYFGTEPLLNRWPFKKIRDIAIKKTMEHIHYEDENSRYITIGCVEKPLMMLACWVEDPNGEAFKKHLSRVADYV
WVGEDGIKM--SFGSQIWDCGLSLQALLASDLIDEIGPVLKKGHEFLKESQIDRNPSGDLKKYRHISKGAWAFSDKDHGWQVSDCTAESMKCCLVFAMMP
PEIVGQQMEPEKLYDAVNVILSLQSKNGGLSAWEPSGAGSWLEWLNPVEFLEDLVIEYEYVECTSSSIQALLLFRKLYPGHRKKEIDKFIVNATQFILDI
QKPDGSWYGNWGICFIYGTWFALTALEAVGKTHENCEAVRRGVDFLLNAQNEDGGWGESYLSCPT-KPLGHTLISLAIM--GL---IHAGQVERDPTPIH
RGAKILINAQLDDGDFPQEELMGVFMRNCMLHYSAYRNIFPIWALSEYRKFVPLPS-
>tr|A0A0D2RC42|A0A0D2RC42_GOSRA Gossypium raimondii chromosome 10, whole genome shotgun sequence (Fragment) OS=Gossypium raimondii GN=B456_010G2233001 PE=4 SV=
MWRLKIGEGGDPYLYSTNNFLGRQTWEFDPNAGTAEERAEVEEARLNFYNNRYNVQPSSDLLWQMQFLKEKKM---IP-QPKIED-GEETYEVRTAAVKR
SVHLFSALQTSQYY---------------IFCRASQR---------------NFPFYLLSSERGWRVICRGHSTMLCTTLNYICLRLLGVGHDGDLNNAC
ERARKWILDRGGVTAISSWGKIWLSILGVYEWSGCNPMPPEFWLFPSYFPINPARMLCYCRLTYLPMSYLYGRKFVGPITPLILQLRQELHTEPYDEIDW
SEKRHLCAKEDLHYPHSLPPILLWDSLYLFSEPLLNRWPFNKLRKKALKVAMDLIHYEDESSRYITIACVIKILCMLACWVEDPNGIYFKKHLARIADYF
WVGEDGMKM--GIASQIWDASLLLQALIATNLYDEIGLTLMKGHNFLKNSQVRNNPSGDFKRFRHISKGSWTYSNGDHGWQVSDCTAESLKCCVSFAMMA
PEMVGEKMEEQQFYDAVNVLLSLQSKNGGYPAWEPAGGAFWWEWLNPVEFLEDLTKEYEYVECTSSSIQALANFKKLYPGHRKIEIENCIRKAAKFLEDV
QYPDGS----------------------------------------------------------------------------------------------
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>tr|A0A0B5D2M9|A0A0B5D2M9_ARTAN Terpene cyclase/mutase family member OS=Artemisia annua PE=2 SV=1
MWRLKIAQGGDPYLYSTNNFAGRQTWEFDPSYGTPEEIAEVEQARLFFWNHRHEVKPSSDVLWRMQFLREKKF---IP-QVKVDDGEEISYDHATTTLRR
SVHFFAALQAEDGHWPAENSGPMYFIQPLVICLYITGHLDSVFPAEHKKEILRYLFCHQNEDGGWGFHIEGHSTMFATTLSYICIRLLGEGPDGGLNGAC
SKARKWIIDRGSATTIPSWGKLWLSVLGVQEWAGINPMPPEFWILPSFIPVHPAKMWCYCRLVYMPMSYLYGTRFVGPITPLVLELRNELYAQPHSEINW
KNTRHLCAKEDLYYPPPLLQNLMWDSLYFLAEPLLTRWPFNK-RKEALKTTMKHIHYEDGNSRYITIGAVEKALCMLACWVEDPSGICFKKHLARIPDYL
WVSEDGMKM--SFGSQQWDASLAIQALLATDLTHEIGPILKKGHDFMKVSQVQDNPSGDFKSYRHISKGSWTFSDQDHGWQLSDCTAEGLKCCLLLSTMP
TEIVGQKLQHEQLSDALNIILSLQSKNGGLAAWEPSHTSAWLEILNPTEFFEDIVIEHEYVECTSSAMQTLVLFKKLYPKNRREEIECFLTGAAGYLEKV
QMPDGSWYGEWSICFIYGTWFAIGGLVAIGKNYKNCLAIRKAVNFLLRTQLEDGGWGESYISCRE-VPEEGGRSNLVQTAWAMMGLIHSKQAERDPMPLH
RAAKLIINSQRKNGDFPEQKSTGCFKKNCALHFPLYKDIFPLWALADYRKKVLPQP-
>tr|M5X7F0|M5X7F0_PRUPE Terpene cyclase/mutase family member (Fragment) OS=Prunus persica GN=PRUPE_ppa017215mg PE=3 SV=1
----------------------------------------------------------------------------------------------------
-----------------------------------------------------------NQDGGWGLHIEGHSTMFCTALSYICMRILGGGPDGGQDNAC
ARARKWILDHGSVTNMPSWGKTWLSILGVFEWSGSNPMPPEFWMLPSFLPMHPAKMWCYCRMVYMPMSYLYGKRFVGPITPLILQLREELYAQPYNEINW
KGVRHHCAKEDIYYPHPWIEDIMWDSLYLCTEPILTRWPFNKIREKALQVTMKHFHYEDENSRYITTGCVEKVLCMLACWAEDPNGDYFKKHLARIPDYL
WVAEDGMKM--SFGSQEWDTGFAIQALLASNLTDEIGPTLARGLDFIEKSQVKDNPSGDFKSYRHISKGSWIFSDQDHGWQVSDCTAEGLKCCLLFSMMR
PDIVGEKMEPERLYDSINVLLSLQSKNGGFAAWEPAGASDWLEMLNPTEFFADIVVEHEYVECTSTAIQALVLFKKLYPGHRKKEIDHSITNATQYIESI
QMPDGSWYGNWGVCFTYGSWFALGGLAAAGKTFNNCLAMRKGVNFLLKTQREWWLGRELPFWWVI-VPLEGNRSNLVHTGWAMMGLIHAGQADRDPAPLH
RAAKLIINSQMENGDFPQQEITGVIMKNCMLHYAAYRNIYPLWALAEYLKWVPLPS-
>tr|K7M9Z1|K7M9Z1_SOYBN Uncharacterized protein OS=Glycine max PE=4 SV=1
MWRLKIADGGDPYIFSTNNFVGRQTWEFDSEAGTAEERAQIEAARQNFYENRFMVKACGDRLWRFQILRENNF---IS-GVKIEDDEKITCEKIRSTMKR
ATHYLSSLQTSDGHWPAHLGGSLFFTPPL-----------------------------------------------------------------------
----------------------------------------------------------------------------------------------------
---------EDLYYPHHWIQDLLWDSLYVFTEPLLNCWPFNKVREKALQVTMKHIHYEDENSRYIAIGCVEKVLCMLACWVEDPNGDAFKKHLARIPDYL
WVSEDGMTM--GIGTQSWDAGFIVQALLATNLIDDFGPTIAKAHDFIKKSQVRENPSGDFKSYRHICKGSWTLADRDHAWQVSDTTAECLKCCLLLSVLP
QDIVGEKMELEKLHDSINLILSLQSKNGGMTAWEPAGAYKWLELLNPTEFFADIVVEHEYLECTASAIQVLVLFKKLYPEHRKEEIENFIAKAVTFIEDT
QLENGSWYGNWAVCFTYSSWFALGGLVAAGKTYTNCVTIRKAVKFLLKIQNKDGGWGESYLSCPR-VPLEGSRSNVVQTSWALMALIHAEQAERDPTPLH
HAAKLLINSQLEDGDWPQQETLGVYLRNCLVHYSFYRNIFPMWALAEYRTNVLLPS-
>tr|A0A067KYR8|A0A067KYR8_JATCU Uncharacterized protein OS=Jatropha curcas GN=JCGZ_06060 PE=4 SV=1
MWRLKIAEGGDPYIYSTNNFLGRQIWEFDPNAGTPEERAEVEEACQNFWKNRFQVKPNADLLWQKQFLREKIF---IP-RVKVKG-FEETHETVTVALRR
SVHVFSALQARDGHWPATNSGSLFFLPPLVFVLYITGYLNTIITEEHRKQILNYIYCHQNEDGGWGLHIEGHSTMFCSVLNYICMRMLAEGPDGGKDNSC
ERAKKWILDHDSAIAIPSWGKIWLSILGLYDWYGTNPVPPEFWAIPSFFPIHPEPLLNS----------------WPFNKLREKALNQTMLHLHYEDEVS
RYITIGSIE--------------------------------------------------------------KPLFMLACWIEDANGDYFKKHLARFSDFL
WVAEDGMTA--SFGSQGWDTSFALQALIACNLTNEIGPTLREGHSFIKNSQVSENPPGDFRRFRHISKGGWTFSDRDHGWQVSDTTAEGLTCCLLFSMMP
PETVGEKLEPEKLFDAVNVILSLQSKNGGLPAWEPAPPTFWMEWLNPTELFEDAVIEHEHVECTSSSIYALALFKKLYPDHRKKEIEDFIANAVQFIQQI
QRPDGSWYGNWGICFTYGTWFALRGLAAAGKTYFNCSA----------------------------VPLEGERSNLVQTAWALMGLIHGGQGEIDPAPLH
LAAKLLINSQTELGDFPQQEILGVYMKNCMVHYAAYRNIFPLWALAEYRQHFSFSS-
>tr|B9SMW6|B9SMW6_RICCO Terpene cyclase/mutase family member OS=Ricinus communis GN=RCOM_0471690 PE=3 SV=1
MWRLKIAERGDPYIYSSNNYLGRQIWEFDPEAGTPEEQAEVEDARQNFWKNRFQVKPSSDLLWQFQALREKKF---IP-KVQVEN-GEETYETTTAALRR
IVNLFTALQASDGHWPATNSGTLFFLPPLIFVLYITGYLNAVITEEHRRQILHYMYCHQNEDGGWGLHIEGHSIMFCTVLNYLCMRMLGEGPDGGEENSC
ERARMWILDHGTAIAIPSWGKIWLSILGLYDWSGTNPVPPEFWAIPSSFPVHPAKMLSYCRMTYLPM-SYLYGKRFVCSVTPLILQLRQEIFNQPYGGIN
WKNVRHLCA--------------------------------------------------------------KPLSMLACWIEDPNGEYFKKHLARFADFL
WVAEDGMTA--TFGSQIWDASFALQALIACDLSDEIGSTLKEGHKFIKNSQVSKNPPGDFKRFRHISKGAWTFSDRDHGWQVSDCTAEALTCCLLFSMMP
L-DVGEKLESKKLFDAVNVLLTLQSSNGGVSAWEPAPSTFWMEWLNPMEFFEDAIIEHEYVECTSSAIHALVLFKNLYSDHRKVEIENFIENAAEFIQDI
QRPDGSWYGNWGICFTYGTWFALRGLTAAGKTYYNCSAVRKGVNFLLKSQREDGGWGESYLSCPK-VPLEGNRSNLVHTAWALMGLIHAGQAQIDPAPLH
LAAKLLINSQTELGDFPQQVIPFL--HACLEKSLSCRKLE-----------------
>sp|Q8W3Z2|LUPS_BETPL Lupeol synthase OS=Betula platyphylla GN=OSCBPW PE=1 SV=1
MWKLKIAEG-GPGLVSGNDFIGRQHWEFDPDAGTPQERAEVEKVREEFTKNRFQMKQSADLLMRMQLRKENPCQPIPP-PVKVKETEVITEEAVITTLRR
SLSFYSSIQAHDGHWPGESAGPLFFLQPFVMALYITGDLNTIFSPAHQKEIIRYLYNHQNEDGGWGFHIEGHSTMFGSALSYIALRILGEGLEDGEDGAM
AKSRKWILDHGGLVAIPSWGKFWVTVLGLYEWSGCNPLPPEFWFLPDIFPIHPGKMLCYCRLVYMPMSYLYGKRFVGPITGLIQSLRQELYNEPYHQINW
NKARSTVAKEDLYYPHPLIQDLLWGFLHHVAEPVLTRWPFSMLREKALKAAIGHVHYEDENSKYLCIGSVEKVLCLIACWAEDPNGEAYKLHLGRIPDNY
WVAEDGLKIQSF-GCQMWDAGFAIQAILSCNLNEEYWPTLRKAHEFVKASQVPENPSGDFKAYRHINKGAWTFSMQDHGWQVSDCTAEGLKVAILFSQMP
PDLVGEKIEKERLYDAVNVILSLQSSNGGFPAWEPQRAYGWLEKFNPTEFFEDTLIEREYVECTSPAVHGLALFRKFYPRHRGTEIDSSIYRGIQYIEDV
QEPDGSWYGHWGICYTYGTWFAVGALAACGRNYKNCPALRKSCEFLLSKQLPNGGWGESYLSSQNWTNIEGNRANLVQTAWALLSLIDARQAEIDPTPIH
RGVRVLINSQMEDGDFPQQEITGVFMRNCTLNYSSYRNIFPIWALGEYRRRVLF---
>sp|Q764T8|LUPS_GLYGL Lupeol synthase OS=Glycyrrhiza glabra GN=LUS1 PE=1 SV=1
MWKLKIGEG-GAGLISVNNFIGRQHWEFDPNAGTPQEHAEIERLRREFTKNRFSIKQSADLLMRMQLRKENHYNNIPA-AVKLSDAENITVEALVTTITR
AISFYSSIQAHDGHWPAESAGPLFFLQPLVMALYITGSLDDVLGPEHKKEIVRYLYNHQNEDGGWGFHIEGHSTMFGSALSYVALRILGEGPQ---DKAM
AKGRKWILDHGGLVAIPSWGKFWVTVLGAYEWSGCNPLPPELWLLPKFAPFHPGKMLCYCRLVYMPMSYLYGKKFVGPITALIRSLREELYNEPYNQINW
NTARNTVAKEDLYYPHPLIQDMLWGFLYHVGERFLNCWPFSMLRRKALEIAINHVHYEDENSRYLCIGSVEKVLCLIARWVEDPNSEAYKLHLARIPDYF
WLAEDGLKIQSF-GCQMWDAAFAIQAILACNVSEEYGPTLRKAHHFVKASQVRENPSGDFNAYRHISKGAWTFSMHDHGWQVSDCTAEGLKAALLLSEMP
SELVGGKMETERFYDAVNVILSLQSSNGGFPAWEPQKAYRWLEKFNPTEFFEDTMIEREYVECTGSAMQGLALFRKQFPQHRSKEIDRCIAKAIRYIENM
QNPDGSWYGCWGICYTYGTWFAVEGLTACGKNCHNSLSLRKACQFLLSKQLPNAGWGESYLSSQNYTNLEGNRANLVQSSWALLSLTHAGQAEIDPTPIH
RGMKLLINSQMEDGDFPQQEITGVFMRNCTLNYSSYRNIFPIWAMGEYRRQVLC---
>sp|O82140|BAMS1_PANGI Beta-Amyrin Synthase 1 OS=Panax ginseng GN=OSCPNY1 PE=1 SV=1
MWKLKIAEGNDPYLYSTNNFVGRQTWEFDPDYVSPGELEEVEQVRRQFWDNRYQVKPSGDLLWRMQFLREKNFRQTIP-QVKVGDDEAVTYEAATTTLRR
AVHFFSALQASDGHWPAENSGPLFFLPPLVMCVYITGHLDTVFPAEHRKEILRYIYCHQNEDGGWGLHIEGHSTMFCTTLSYICMRILGEGPDGGVNNAC
ARGRKWILDHGSVTAIPSWGKTWLSILGVYEWIGSNPMPPEFWILPSFLPMHPAKMWCYCRMVYMPMSYLYGKRFVGPITPLILQLREELYGQPYNEINW
RKTRRVCAKEDIYYPHPLIQDLLWDSLYVLTEPLLTRWPFNKLREKALQTTMKHIHYEDENSRYITIGCVEKVLCMLVCWVEDPNGDYFRKHLARIPDYI
WVAEDGMKMQSF-GSQEWDTGFSIQALLDSDLTHEIGPTLMKGHDFIKKSQVKDNPSGDFKSYRHISKGSWTFSDQDHGWQVSDCTAEGLKCCLIFSTMP
EEIVGKKIKPERLYDSVNVLLSLQRKNGGLSAWEPAGAQEWLELLNPTEFFADIVIEHEYVECTSSAIQALVLFKKLYPGHRKKEIDNFITNAVRYLEDT
QMPDGSWYGNWGVCFTYGSWFALGGLAAAGKTYYNCAAVRKAVEFLLKSQMDDGGWGESYLSCPKYVPLEGNRSNLVHTGWALMGLIHSEQAERDPTPLH
RAAKLLINSQMEDGDFPQQEISGVFMKNCMLHYAAYRNIYPLWALAEYRRRVPL---
>sp|Q8W3Z1|BAMS_BETPL Beta-amyrin synthase OS=Betula platyphylla GN=OSCBPY PE=1 SV=1
MWRLKIADGGDPYIYSTNNFVGRQTWEFDPQAGSPQERAEVEEARRNFYDNRYQVKPSGDLLWRMQFLKEKNFKQTIP-PVKVEDGEEITYEKSTAALRR
AVHFYSALQASDGHWPAENAGPLFFLPPLVMCMYITGHLNTVFPAEHQKEILRYIYYHQNEDGGWGLHIEGHSTMFCTALSYICMRILGEGPDGGQDNAC
ARARKWILDHGGVTHMPSWGKTWLSILGIFEWIGSNPMPPEFWILPSFLPMHPAKMWCYCRMVYMPMSYLYGKRFVGPITPLILQLREELYTQPYHQVNW
KKVRHLCAKEDIYYPHPLIQDLLWDSLYIFTEPLLTRWPFNKLREKALQVTMKHIHYEDENSRYITIGCVEKVLCMLACWVEDPNGDYFKKHIARIPDYI
WVAEDGIKMQSF-GSQEWDTGFAIQALLASNLTDEIGPTLARGHDFIKKSQVKDNPSGDFESHRHISKGSWTFSDQDHGWQVSDCTAEGLKCCLLFSIMP
PEIVGEKMEPEQLYDSVNVLLSLQSKNGGLAAWEPAGAQEWLELLNSTEFFADIVIEHEYIECTASAMQTLVLFKKLYPGHRKKEIENFIKNAAQFLQVI
QMPDGSWYGNWGVCFTYGTWFALGGLAAVGKTYNNCLAVRRAVDFLLRAQRDNGGWGESYLSCPKYVPLEGNKSNLVHTAWAMMGLIHAGQAERDPTPLH
RAAKLIINSQLEDGDFPQQEITGVFMKNCMLHYAAYKNIYPLWALAEYRKHVPL---
>sp|O82146|BAMS2_PANGI Beta-Amyrin Synthase 2 OS=Panax ginseng GN=OSCPNY2 PE=2 SV=1
MWRLMTAKGGDPYLYSTNNFIGRQTWEFDPDYGTPAERAEVEEARLHFWNNRYQVKPSSDVLWRMQFLKEKNFKQIIP-QVKVEDGEEITYEAATTTLRR
AVHYFSALQADDGHWPAENAGPLFFLPPLVMCLYITGHLNTVFPAEHRIEILRYIYCHQNDDGGWGLHIEGHSTMFCTALSYICMRILGEGRDGGENNAC
ARARKWILDHGSVTAIPSWGKTWLSILGLFDWSGSNPMPPEFWILPPFLPMHPAKMWCYCRMVYMPMSYLYGKRFVGPITPLILQLREELYAQAYDEINW
RKVRHNCAKEDLYYPHPLIQDLMWDSLYIFTEPFLTRWPFNKLREKALQTTMKHIHYEDENSRYITIGCVEKVLCMLACWVEDPNGDYFKQHLARIPDYI
WVAEDGMKMQSF-GSQEWDTGFAIQALLASDLIDEIRPTLMKGHDFIKKSQVKENPSGDFKSHRHISKGSWTFSDQDHGWQVSDCTAEALKCCLLFSRMP
TEIVGDKMEDNQLFDAVNMLLSLQSKNGGLAAWEPAGSSEWLELLNPTEFFEDIVIEHEYVECTSSAIQAMVMFKKLYPGHRKKEIEVSITNAVQYLEDI
QMPDGSWYGNWGVCFTYGTWFAMGGLTAAGKTYNNCQTLHKAVDFLIKSQRSDGGWGESYLSCPNYTPLEGNRSNLVHTSWAMMGLIHSRQAERDPTPLH
RAAKLLINSQMESGDFPQQEITGVFMKNCMLHYAASRNIYPLWALAEYRKNVRL---
>sp|E2IUA6|TARS_KALDA Taraxerol synthase OS=Kalanchoe daigremontiana PE=1 SV=1
MWKLKIAQGGDPYLYSTNNYVGRQTWEFDPEAGTPEERAEVEAARLNFYNNRYRVKPSADLLYRMQFLKEKNFKQTIP-PVKVEDGEEITYETATTALKR
AVHFYSALQASDGHWPAENSGPLFFLPPLVMCLYITGHLNTVFPAEHQREILRYIYYHQNEDGGWGLHIEGHSTMFCTALSYICMRILGEGPDGGLDNAV
ARGRKWILDHGTVTAMPSWGKTWLSIMGLFDWSGSNPMPPEFWLLPSFLPMYPAKMWCYCRMVYMPMSYLYGKRFVGPITPLILQLREELYDQPYEQVNW
KQVRHECAKEDIYYPHPKIQDLLWDTLYIAIEPLLTRWPFNKLRERALQRTMKHIHYEDENSRYITIGCVEKVLCMLACWVEDPNGDYFKKHLARVPDYI
WVAEDGMKMQSF-GSQQWDTGFAIQALLASNMSDEIGETLAKGHDFVKKSQVKDNPSGDFKSHRHISKGSWTFSDQDHGWQVSDCTAEGLKCCLLFSLMP
PELVGEKMEPERLYDSVNILLSLQSKNGGLAAWEPAGAPEWLELLNPTEFFADIVIEHEYVECTASAIQALVLFKKLYPGHRKKDIETFIKGAAQYIEDR
QMPDGSWYGSWGVCFTYGTWFALGGLAAAGKNYDNCAAIRKGTEFLLNTQCENGGWGESYRSCPEYVPLEENKSNLVHTAWALMGLIHSRQAERDITPLH
RAAKLLINSQLENGDFPQQEITGVFMKNCMQHYAAYRNIYPLWGIAEYRKQIPL---
>sp|A8CDT2|BAS_BRUGY Beta-amyrin synthase OS=Bruguiera gymnorhiza GN=BAS PE=1 SV=1
MWRIKIAEGGDPYLYSTNNYVGRQTWEFDPDAGTPEERAEVEEARQNFYKNRYQVKPCGDLLWRLQFLGEKNFEQTIP-QVRIEEGEGITYEKATRALRR
TVQFFSALQASDGHWPAEIAGPLFFLPPLVMCVYITGHLDAVFPAEHRKEILRYIYYHQNEDGGWGLHIEGHSTMFCTALNYICMRIIGEGPNGGQDDAC
ARARKWIHDHGSVTNIPSWGKTWLSILGVYDWSGSNPMPPEFWMLPSFLPMHPAKMWCYCRMVYMPMSYLYGKRFVGPITPLIQQLREELFTQPYDQINW
KKTRHQCAPEDLYYPHPFVQDLIWDCLYIFTEPLLTRWPLNEIRKKALEVTMKHIHYEDESSRYITIGCVEKVLCMLACWVEDPNGDYFKKHLARIPDYI
WVAEDGMKMQSF-GSQEWDTGFAIQALLATNLTDEIGDVLRRGHDFIKKSQVRDNPSGDFKSYRHISKGSWTFSDQDHGWQVSDCTAEGLKCCLLFSMMP
PEIVGEHMVPERLYDSVNVLLSLQSKNGGLSAWEPAGAQEWLELLNPTEFFADIVIEHEYVECTSSAIHALVLFKKLYPGHRKKEIDNFIVNAVRYLESI
QTSDGGWYGNWGVCFTYGTWFALGGLAAAGKTYNNCLAMRKAVDFLLRIQRDNGGWGESYLSCPEYVPLEGNRSNLVHTAWALMALIHAGQMDRDPTPLH
RAARLMINSQLEDGDFPQQEITGVFMKNCMLHYAAYRNIYPLWALAEYRRRVPL---
>sp|E7DN63|BAMS_SOLLC Beta-amyrin synthase OS=Solanum lycopersicum GN=TTS1 PE=1 SV=1
MWKLKIAEGQGPYLYSTNNYVGRQTWEFDPNGGTIEERAKIEEARQQFWNNRYKVKPSSDLLWRIQFLGEKNFKQKIP-AVKVEEGEEISHEVATIALHR
AVNFFSALQATDGHWPAENAGPLFFLPPLVMCMYITGHLNTVFPAEHRKEILRYIYCHQNEDGGWGLHIEGHSTMFCTALSYICMRILGEGPDGGVNNAC
ARARKWILDHGSVTAIPSWGKTWLSILGVFEWIGTNPMPPEFWILPSFLPVHPAKMWCYCRMVYMPMSYLYGKRFVGPITPLILQLREELYDRPYDEINW
KKVRHVCAKEDLYYPHPLVQDLMWDSLYICTEPLLTRWPFNKLRNKALEVTMKHIHYEDENSRYITIGCVEKVLCMLACWVEDPNGDYFKKHLARIPDYL
WVAEDGMKMQSF-GSQEWDTGFAIQALLASEMNDEIADTLRKGHDFIKQSQVTNNPSGDFKGYRHISKGSWTFSDQDHGWQVSDCTAEALKCCLLLSTMP
RELVGQAMEPGRLYDSVNVVLSLQSKNGGLAAWEPAGASEYLELLNPTEFFADIVIEHEYVECTASSIQALVLFKKLYPGHRTKEINIFIDNAVKYLEDV
QMPDGSWYGNWGVCFTYGSWFALGGLVAAGKSYNNSAAVRKGVEFLLRTQRSDGGWGESYRSCPDYRELETNDSNLVQTAWALMGLIHSGQADRDPKPLH
RAAKLLINSQMEDGDFPQQEITGVFMKNCMLHYAAYRNIYPLWGLAEYRKNVLL---
>sp|Q9LRH8|BAMS_PEA Beta-amyrin synthase OS=Pisum sativum GN=OSCPSY PE=2 SV=1
MWRLKIAEGGDPYLFSTNNFVGRQTWEYDPEAGSEEERAQVEEARRNFYNNRFEVKPCGDLLWRFQVLRENNFKQTIG-GVKIEDEEEITYEKTTTTLRR
GTHHLATLQTSDGHWPAQIAGPLFFMPPLVFCVYITGHLDSVFPPEHRKEILRYIYCHQNEDGGWGLHIEGHSTMFCTALNYICMRILGEGPDGGEDNAC
VRARNWIRQHGGVTHIPSWGKTWLSILGVFDWLGSNPMPPEFWILPSFLPMHPAKMWCYCRLVYMPMSYLYGKRFVGPITPLILQLREELHTEPYEKINW
TKTRHLCAKEDIYYPHPLIQDLIWDSLYIFTEPLLTRWPFNKLRKRALEVTMKHIHYEDENSRYLTIGCVEKVLCMLACWVEDPNGDAFKKHIARVPDYL
WISEDGMTMQSF-GSQEWDAGFAVQALLATNLIEEIKPALAKGHDFIKKSQVTENPSGDFKSHRHISKGSWTFSDQDHGWQVSDCTAEGLKCCLLLSLLP
PEIVGEKMEPERLFDSVNLLLSLQSKKGGLAAWEPAGAQEWLELLNPTEFFADIVVEHEYVECTGSAIQALVLFKKLYPGHRKKEIENFIFNAVRFLEDT
QTEDGSWYGNWGVCFTYGSWFALGGLAAAGKTYTNCAAIRKGVKFLLTTQREDGGWGESYLSSPKYVPLEGNRSNVVHTAWALMGLIHAGQSERDPTPLH
RAAKLLINSQLEQGDWPQQEITGVFMKNCMLHYPMYRDIYPLWALAEYRRRVPL---
>sp|E2IUA9|LUPS_KALDA Lupeol synthase OS=Kalanchoe daigremontiana PE=1 SV=1
MWKLKIADGGNPYIFTTNNFVGRQIWEFDPQATDPQQLAKVEAARLDFYHNRYKLKPNSDLLWRMQFLEEKAFTQTIP-QVKVEDGEEVSYEAVTAALRR
GVHLYSALQASDGHWPAENAGPMFFMPPMVMCLYITGHLNAIFTEEHRSETLRYIYYHQNEDGGWGFHIEGHSTMFGTVLNYICMRLLGEGPEGGQDNAV
SRGRKWILDHGGATSIPSWGKTWLSIMGLCDWSGCNPMPPEFWLLPSYLPMHPGKMWCYCRMVYMPMSYLYGKRFTARITPLILQLREEIHIQPYDQIDW
KKVRHVCCKEDMYYPHPLLQDLLWDTLYLTTEPLLTRWPLNKLRKRALQTTMKHIHYEDENSRYITIGCVEKVLCMLACWVEDPNGDYFKKHLARIPDYL
WIAEDGMKMQSF-GSQHWDTAFSIQALLASNMAEEIGITLAKGHDFIKKSQVKDNPSGDFKGYRHISKGAWTFSDQDHGWQVSDCTAEGLKCCLLFSMMQ
PEVVGESMAPESLYNSVNVLLSLQSQNGGLPAWEPAGAPEWLELLNPTEFFENIVIEHEYVECTSSAVQALVLFKKLYPLHRRKEVERFITNGAKYLEDI
QMPDGSWYGNWGVCFTYGAWFALEGLSAAGKTYNNCAAVRKGVDFLLNIQLEDGGWGESYQSCPDYVPLEDNRSNLVQTSWALMGLIYAGQADRDPTPLH
RAAQLLINSQLEDGDFPQQEITGVFQRNCMLHYAAYRNIFPLWALAEYRRQIQL---
>sp|Q8W3Z3|CAS2_BETPL Cycloartenol synthase 2 OS=Betula platyphylla GN=CASBPX2 PE=1 SV=1
MWKLKIAE-GSPWLRTLNNHVGRQVWEFDPKLG-PEELAEIERARETSLKVRFEKKHSSDLLMRIQFAKENPRAV-LP-QVKVNETEDVTEEMVTRMLRR
AISFHSTLQAHDGHWAGDYGGPMFLMPGLVITLSITGALNTVLSEEHKKEMCRYLYNHQNKDGGWGLHIEGPSTMFGTVLSYVTLRLLGEGANDGQG-AI
ERGRKWILDHGSATAIISWGKMWLSVLGAFEWSGNNPLPPEIWLLPYMLPVHPGRMWCHCRMVYLPMSYLYGKRFVGPITPTVMSLRKELYSVPYHEIDW
NQARNLCAKEXLYYPHPLVQDILWASLHKLVEPVLMRWPGKRLREKALRTVLEHIHYEDENTRYICIGPVNKVLNMLCCWVEDPNSEAFKLHLPRINDYL
WIAEDGMKMQGYNGSQLWDTAFAVQAIISTNLFEEYGPTLEKAHMYIKKSQVREDCPGDLDFYRHISKGAWPFSTADHGWPISDCTAEGLKAALLLSKIP
PDVVGEPLVEERLYDAVNVILSLQNADGGFATYELTRSYPWLELINPAETFGDIVIDYNYVECTSAAIQALTSFKKSYPKHREEEVDVCIKRAAMFTEKI
QASDGSWYGSWGVCFTYGTWFGVKGLVAAGKNFNDCFGIRKACDFLLSKQLPSGGWGESYLSCQNYSHVEGNRSHVVNTGWAMLALIEAGQAERDPTPLH
RAARVLINSQMENGDFPQEEIMGVFNRNCMITYAAYRNIFPIWALGEYRCRVLQ---
>sp|Q2XPU7|LUPS_RICCO Lupeol synthase OS=Ricinus communis PE=1 SV=1
MWRIKIAEGGNPYIYSTNNFQGRQIWVFDPNAGTPEEQAEVEEARQNFWKNRFQVKPNSDLLWQLQFLREKNFKQKIP-KVKVEDGEEITSEIAAAALRR
SVHLFSALQASDGHWCAENGGLLFFLPPLVFAVYITGHLNTVFSPEHRKEILRYIYCHQNEDGGWGIHIEGHSTMFCTVLNYICMRILGEARDGGIENAC
ERGRKWILDHGGATGISSWGKTWLSILGVYEWDGTNPMPPEFWAFPSSFPLHPAKMFCYCRITYMPMSYLYGKRFVGPITPLILQIREEIYNEPYNKIKW
NSVRHLCAKEDNYFPHPTIQKLLWDALYTFSEPLFSRWPFNKLREKALKITMDHIHYEDHNSRYITIGCVEKPLCMLACWIEDPHGEAFKKHLARIADYI
WVGEDGIKMQSF-GSQTWDTSLALQALIASDLSHEIGPTLKQGHVFTKNSQATENPSGDFRKFRHISKGAWTFSDKDQGWQVSDCTAESLKCCLLFSMMP
PEIVGEKMEPEKVYDSVNVILSLQSQNGGFTAWEPARAGSWMEWLNPVEFMEDLVVEHEYVECTSSAIQALVLFKKLYPRHRNKEIENCIINAAQFIENI
QEPDGSWYGNWGICFSYGTWFALKGLAAAGRTYENCSAIRKGVDFLLKSQRDDGGWAESYLSCPKYVPFEGNRSNLVQTAWAMMGLIYGGQAKRDPMPLH
RAAKLLINSQTDLGDFPQQELTGAFMRNCMLHYALFRNTFPIWALAEYRRHVLF---
>sp|E7DN64|DAMS_SOLLC Delta-amyrin synthase OS=Solanum lycopersicum GN=TTS2 PE=1 SV=1
MWKLKIAKGQDRYLYSTNNYIGRQIWEFDPNAGTIEEQAKIEEARQHYWNNRYKVKPNSDLLWRMQFLREKNFKQRIR-AVKVEEGEEISHEIATVALHR
AVHFFSALQATDGHWPAESAGPLFFLPPLVMCMYITGHLNTVFPAEHRKEILRYIYCHQNEDGGWGLHIEGHSTMFCTAMSYICMRILGEGPEGGVNNAC
ARARKWILDHGSVIAIPSWGKTWLSILGAFEWIGTNPMPPEFWILPSFLPVHPAKMWCYCRTVYMPMSYLYGKRFVGPITPLILKLREELYDQTYDEINW
KKVRHVCAKEDLYYPHPFVQDLMWDSLYICTEPLLTRWPFNKLRNKALEVTMKHIHYEDENSRYITMGCVEKVLSMLACWVEDPNGDHFKKHLARIPDFL
WVAEDGMKMQGC-GSQSWDASLAIQALLASEMNDEISDTLKNGHDFIKQSQVKDNPSGDFKVYRHISKGSWAFADQDLGWQVSDCTAEALKCCLLFSTMP
PEIVGEAMDPVRLYDSVNVILSLQSKNGGLSAWEPAGAPEYLELLNPTEFFEDIVIEHEHVECTSSAIQALVRFKKLYPGHRTTEVDNFINNGVKYIEDV
QEPDGSWYGNWGVCFIYASWFALGGLAAVGLSYSNCAAVRKSVEFLLRTQRSDGGWGESYRSCPDYRELETEHSNLVQTAWALMGLIHSGQVERDPRPLH
RAAKLLINFQMEDGDFPQQEITGVFLRNCMMHYALYRNIFPLWGLAEYRRNVLV---
>sp|P38605|CAS1_ARATH Cycloartenol synthase OS=Arabidopsis thaliana GN=CAS1 PE=1 SV=2
MWKLKIAE-GSPWLRTTNNHVGRQFWEFDPNLG-PEDLAAVEEARKSFSDNRFVQKHSADLLMRLQFSRENLIPV-LP-QVKIEDTDDVTEEMVETTLKR
GLDFYSTIQAHDGHWPGDYGGPMFLLPGLIITLSITGALNTVLSEQHKQEMRRYLYNHQNEDGGWGLHIEGPSTMFGSVLNYVTLRLLGEGPNDGDG-DM
EKGRDWILNHGGATNITSWGKMWLSVLGAFEWSGNNPLPPEIWLLPYFLPIHPGRMWCHCRMVYLPMSYLYGKRFVGPITSTVLSLRKELFTVPYHEVNW
NEARNLCAKEDLYYPHPLVQDILWASLHKIVEPVLMRWPGANLREKAIRTAIEHIHYEDENTRYICIGPVNKVLNMLCCWVEDPNSEAFKLHLPRIHDFL
WLAEDGMKMQGYNGSQLWDTGFAIQAILATNLVEEYGPVLEKAHSFVKNSQVLEDCPGDLNYYRHISKGAWPFSTADHGWPISDCTAEGLKAALLLSKVP
KAIVGEPIDAKRLYEAVNVIISLQNADGGLATYELTRSYPWLELINPAETFGDIVIDYPYVECTSAAIQALISFRKLYPGHRKKEVDECIEKAVKFIESI
QAADGSWYGSWAVCFTYGTWFGVKGLVAVGKTLKNSPHVAKACEFLLSKQQPSGGWGESYLSCQDYSNLDGNRSHVVNTAWAMLALIGAGQAEVDRKPLH
RAARYLINAQMENGDFPQQEIMGVFNRNCMITYAAYRNIFPIWALGEYRCQVLL---
>sp|E2IUA8|FRIES_KALDA Friedelin synthase OS=Kalanchoe daigremontiana PE=1 SV=1
MWKLKIAEGGDPYIYTTNNFVGRQIWEFDPQATDPQQLAKVEAARLNFYNHRHKIKPSSDLLWRLQFLEEKDFRQNIA-QVKVEDGEEVSYEAATAALKR
GVHFYSALQASDGHWPAENAGPMFFMSPLVMCLYITGHLNTIFTEEHRRETLRYIYYHQNEDGGWGFHIEGQSTMFGTVLNYICMRLLGEGPEGGQDNAV
SRGRKWILDHGGATAIPSWGKTWLSIMGLCDWSGCNPMPPEFWLLPSYLPMHPAKMWCYCRMVYMPMSYLYGKRFTTHITPLILQLREELHTQPYDQINW
KKVRHVCCKEDTYYPHPILQDLIWDTLYLTTEPLLTRWPLNKLRERALKKTMKHIHYEDENSRYIVIGAVEKVLCMLACWVEDPNGDYFKKHLARVPDYF
WVAEDGMKIQSF-GSQHWDTAFFVQALLASDMTDEIRTTLAKAHDCIKKSQVKDNPSGDFRSYRHISKGAWTFSDQDHGWQLSDCTAEGLKCCLLFSLMQ
PEVVGEAMPPERLYDSVNVLLYLQSKNGGMPGWEPAGESEWLELLNPTEFFENIVIEHEYVECTSSAVQALVLFKKLYPLHRRKEVERFITNGAKYLEDI
QMPDGSWYGNWGVCFTYGAWFALEGLSAAGKTYNNCAAVRKGVDFLLNIQLEDGGWGESYQSCPDYVPLEDNRSNLVQTSWALMGLIYAGQADRDPTPLH
RAAKLLINSQLEDGDFPQQEIAGVFKMNCTLHFAAYRNIFPIWALAVYRRFCNP---
>sp|Q2XPU6|CAS1_RICCO Cycloartenol synthase OS=Ricinus communis PE=1 SV=1
MWKLRIAE-GNPWLRTTNDHIGRQVWEFDSKIG-PEELSQIENARQNFTKNRFIHKHSSDLLMRIQFSKENPIEV-LP-QVKVKESEQVTEEKVKITLRR
ALNYYSSIQADDGHWPGDYGGPMFLMPGLIIALSITGALNAILSEEHKREMCRYLYNHQNRDGGWGLHIEGPSTMFGSVLCYVSLRLLGEGPNEGEG-AV
ERGRNWILKHGGATAITSWGKMWLSVLGAYEWSGNNPLPPEMWLLPYILPVHPGRMWCHCRMVYLPMSYLYGKRFVGPITPTVLSLRKELYTVPYHEIDW
NQARNQCAKEDLYYPHPMLQDVLWATLHKFVEPILMHWPGKRLREKAIQTAIEHIHYEDENTRYICIGPVNKVLNMLCCWVEDPNSEAFKLHLPRLYDYL
WLAEDGMKMQGYNGSQLWDTAFAVQAIVSTNLIEEYGPTLKKAHSFIKKMQVLENCPGDLNFYRHISKGAWPFSTADHGWPISDCTAEGIKALMLLSKIP
SEIVGEGLNANRLYDAVNVVLSLQNGDGGFPTYELSRSYSWLEFINPAETFGDIVIDYPYVECTSAAIQALTSFRKSYPEHQREEIECCIKKAAKFMEKI
QISDGSWYGSWGVCFTYGTWFGIKGLVAAGKSFGNCSSIRKACDFLLSKQCPSGGWGESYLSCQKYSNLEGDRSHVVNTAWAMLSLIDAGQAERDPTPLH
RAARYLINAQMENGDFPQQEIMGVFNRNCMITYAAYRDIFPIWALGEYRCRVLK---
>sp|Q9SXV6|CAS1_GLYGL Cycloartenol synthase OS=Glycyrrhiza glabra GN=GgCAS1 PE=1 SV=1
MWKLKIAE-GSPWLRTVNNHVGRQVWEFDPKLG-PEDLLEIEKARQNFHDNRFTHKHSADLLMRIHFAKENPMEV-LP-KVRVKDIEDVTEETVKTTLRR
AINFHSTLQSHDGHWPGDYGGPMFLMPGLVITLSITGALNAVLTEEHRKEICRYLYNHQNKDGGWGLHIEGPSTMFGSVLNYVALRLLGEGPNDRQG-EM
EKGRDWILGHGGATFITSWGKMWLSVLGVYEWSGNNPLPPEIWLLPYVLPIHPGRMWCHCRMVYLPMSYLYGKRFVGPITPTILSLRKELYTIPYHDIDW
NQARNLCAKEDLYYPHPLVQDILWASLHKFLEPILMHWPGKKLREMAIKTAIEHIHYEDDNTRYLCIGPVNKVLNMLCCWVEDPNSEAFKLHLPRIYDYL
WIAEDGMKMQGYNGSQLWDTAFTAQAIISSNLIEEYGPTLRKAHTYIKNSQVLEDCPGDLSKYRHISKGAWPFSTADHGWPISDCTAEGLKAVLLLSKIA
PEIVGEPLDAKRLYDAVNVILSLQNEDGGFATYELTRSYTWLELINPAETFGDIVIDYPYVECTSAAIQALTSFKKLYPGHRREEIQCCIEKAASFIEKT
QASDGSWYGSWGVCFTYGTWFGVKGLIAAGKSFNNCSSIRKACEFLLSKQLPSGGWGESYLSCQNYSNVESNRSHVVNTGWAMLALIDAEQAKRDPTPLH
RAAVYLINSQMENGDFPQQEIMGVFNKNCMITYAAYRNVFPIWALGEYRHRVLQ---
>sp|O82139|CAS1_PANGI Cycloartenol Synthase OS=Panax ginseng GN=OSCPNX1 PE=1 SV=1
MWKLKIAE-GNPWLRTLNDHVGRQIWEFDPNIG-PEELAEVEKVRENFRNHRFEKKHSADLLMRIQFANENPGVV-LP-QVKVNDGEDISEDKVTVTLKR
AMSFYSTLQAHDGHWPGDYGGPMFLMPGLVITLSITGVLNVVLSKEHKREICRYLYNHQNRDGGWGLHIEGPSTMFGTVLNYVTLRLLGEGANDGQG-AM
EKGRQWILDHGSATAITSWGKMWLSVLGVFEWSGNNPLPPETWLLPYILPIHPGRMWCHRRMVYLPMSYLYGKRFVGPITPTVLSLRKEVFSVPYHEIDW
NQARNLCAKEDLYYPHPLIQDILWASLDKVWEPIFMHWPAKKLREKSLRTVMEHIHYEDENTRYICIGPVNKVLNMLCCWVEDPNSEAFKLHLPRLHDFL
WLAEDGMKMQGYNGSQLWDTAFAVQAIISTNLAEEYGPTLRKAHTFMKNSQVLDDCPGDLDAYRHVSKGAWPFSTADHGWPISDCTAEGFKAVLQLSKLP
SELVGEPLDAKRLYDAVNVILSLQNSDGGYATYELTRSYSWLELVNPAETFGDIVIDYPYVECTSAAIQALTAFKKLFPGHRREEIQHSIEKAALFIEKI
QSSDGSWYGSWGVCFTYGTWFGIKGLVTAGRTFSSCASIRKACDFLLSKQVASGGWGESYLSCQNYTNLEGNRSHVVNTGWAMLALIDAGQAERDATPLH
RAAKLLINSQMENGDFPQEEIMGVFDKNCMITYAAYRNIFPIWALGEYRCRVLQ---
>sp|B6EXY6|LUP4_ARATH Beta-amyrin synthase OS=Arabidopsis thaliana GN=BAS PE=1 SV=2
MWRLKIGEGNDPYLFTTNNFAGRQTWEFDPDGGSPEERHSVVEARRIFYDNRFHVKASSDLLWRMQFLREKKFEQRIA-PVKVEDSEKVTFETATSALRR
GIHFFSALQASDGHWPAENAGPLFFLPPLVFCLYITGHLDEVFTSEHRKEILRYIYCHQKEDGGWGLHIEGHSTMFCTTLNYICMRILGESPDGGHDNAC
GRAREWILSHGGVTYIPSWGKTWLSILGVFDWSGSNPMPPEFWILPSFFPVHPAKMWSYCRMVYLPMSYLYGKRFVGPITSLILQLRKELYLQPYEEINW
MKVRHLCAKEDTYYPRPLVQELVWDSLYIFAEPFLARWPFNKLREKALQLAMKHIHYEDENSRYITIGCVEKVLCMLACWVEDPNGDYFKKHLSRISDYL
WMAEDGMKMQSF-GSQLWDTGFAMQALLASNLSSEISDVLRRGHEFIKNSQVGENPSGDYKSYRHISKGAWTFSDRDHGWQVSDCTAHGLKCCLLFSMLA
PDIVGPKQDPERLHDSVNILLSLQSKNGGMTAWEPAGAPKWLELLNPTEMFSDIVIEHEYSECTSSAIQALSLFKQLYPDHRTTEITAFIKKAAEYLENM
QTRDGSWYGNWGICFTYGTWFALAGLAAAGKTFNDCEAIRKGVQFLLAAQKDNGGWGESYLSCSKYIAQVGEISNVVQTAWALMGLIHSGQAERDPIPLH
RAAKLIINSQLESGDFPQQQATGVFLKNCTLHYAAYRNIHPLWALAEYRARVSL---
>sp|Q8RWT0|LUP2_ARATH Amyrin synthase LUP2 OS=Arabidopsis thaliana GN=LUP2 PE=1 SV=1
MWKLKIGEGNDPYLFSSNNFVGRQTWEFDPKAGTPEERAAVEDARRNYLDNRPRVKGCSDLLWRMQFLKEAKFEQVIP-PVKIDDGEGITYKNATDALRR
AVSFYSALQSSDGHWPAEITGTLFFLPPLVFCFYITGHLEKIFDAEHRKEMLRHIYCHQNEDGGWGLHIEGKSVMFCTVLNYICLRMLGEGPNGGRNNAC
KRARQWILDHGGVTYIPSWGKIWLSILGIYDWSGTNPMPPEIWLLPSFFPIHLGKTLCYTRMVYMPMSYLYGKRFVGPLTPLIMLLRKELHLQPYEEINW
NKARRLCAKEDMIYPHPLVQDLLWDTLHNFVEPILTNWPLKKLREKALRVAMEHIHYEDENSHYITIGCVEKVLCMLACWIENPNGDHFKKHLARIPDFM
WVAEDGLKMQSF-GSQLWDTVFAIQALLACDLSDETDDVLRKGHSFIKKSQVRENPSGDFKSYRHISKGAWTLSDRDHGWQVSDCTAEALKCCMLLSMMP
AEVVGQKIDPEQLYDSVNLLLSLQGEKGGLTAWEPVRAQEWLELLNPTDFFTCVMAEREYVECTSAVIQALVLFKQLYPDHRTKEIIKSIEKGVQFIESK
QTPDGSWHGNWGICFIYATWFALSGLAAAGKTYKSCLAVRKGVDFLLAIQEEDGGWGESHLSCPEYIPLEGNRSNLVQTAWAMMGLIHAGQAERDPTPLH
RAAKLIITSQLENGDFPQQEILGVFMNTCMLHYATYRNIFPLWALAEYRKAAFA---
>sp|Q6BE25|CAS1_CUCPE Cycloartenol synthase OS=Cucurbita pepo GN=CPX PE=1 SV=1
MWQLKIGAAG-GWLSTLNNHVGRQVWHFHPELG-PEDLQQIQQARQHFSDHRFEKKHSADLLMRMQFAKENSSVN-LP-QVKVKDKEDVTEEAVTRTLRR
AINFYSTIQADDGHWPGDYGGPMFLIPGLVITLSITGALNAVLSTEHQREICRYLYNHQNKDGGWGLHIEGPSTMFGSVLNYVTLRLLGEEAEDGQG-AV
DKARKWILDHGGAAAITSWGKMWLSVLGVYEWAGNNPLPPELWLLPYLLPCHPGRMWCHCRMVYLPMCYLYGKRFVGPITPIIRSLRKELYLVPYHEVDW
NKARNQCAKEDLYYPHPLVQDILWATLHHVYEPLFMHWPAKRLREKALQSVMQHIHYEDENTRYICIGPVNKVLNMLCCWAEDPHSEAFKLHIPRIYDYL
WIAEDGMKMQGYNGSQLWDTAFAVQAIISTELAEEYETTLRKAHKYIKDSQVLEDCPGDLQSYRHISKGAWPFSTADHGWPISDCTAEGLKAVLLLSKLP
SEIVGKSIDEQQLYNAVNVILSLQNTDGGFATYELTRSYRWLELMNPAETFGDIVIDYPYVECSSAAIQALAAFKKLYPGHRRDEIDNCIAEAADFIESI
QATDGSWYGSWGVCFTYGGWFGIRGLVAAGRRYNNCSSLRKACDFLLSKELAAGGWGESYLSCQNYTNIKDDRPHIVNTGWAMLSLIDAGQSERDPTPLH
RAARVLINSQMEDGDFPQEEIMGVFNKNCMISYSAYRNIFPIWALGEYRSRVLK---
>sp|Q6Z2X6|CAS_ORYSJ Cycloartenol synthase OS=Oryza sativa subsp. japonica GN=Os02g0139700 PE=1 SV=1
MWRLRVAE-GDPWLRTKNGHVGRQVWEFDPAAG-PDELAAVEAARRGFAARRHELKHSSDLLMRMQFAKANPLLD-IP-AIKLEEHEAVTGEAVLSSLKR
AIARYSTFQAHDGHWPGDYGGPMFLMPGLIITLYVSGALNTALSSEHQKEIRRYLYNHQNEDGGWGLHIEGHSTMFGSALTYVSLRLLGEGPDSGDG-AM
EKGRKWILDHGGATYITSWGKFWLSVLGVFDWSGNNPVPPEIWLLPYFLPIHPGRMWCHCRMVYLPMCYIYGKRFVGPVTPIILELRKELYEVPYNEVDW
DKARNLCAKEDLYYPHPFVQDVLWATLHKFVEPAMLRWPGNKLREKALDTVMQHIHYEDENTRYICIGPVNKVLNMLACWIEDPNSEAFKLHIPRVHDYL
WIAEDGMKMQGYNGSQLWDTAFTVQAIVATGLIEEFGPTLKLAHGYIKKTQVIDDCPGDLSQYRHISKGAWPFSTADHGWPISDCTAEGLKAALLLSKIS
PDIVGEAVEVNRLYDSVNCLMSYMNDNGGFATYELTRSYAWLELINPAETFGDIVIDYPYVECTSAAIQALTAFKKLYPGHRKSEIDNCISKAASFIEGI
QKSDGSWYGSWAVCFTYGTWFGVKGLVAAGRTFKNSPAIRKACDFLLSKELPSGGWGESYLSSQDYTNLEGKRPHAVNTGWAMLALIDAGQAERDPIPLH
RAAKVLINLQSEDGEFPQQEIIGVFNKNCMISYSEYRNIFPIWALGEYRRRVLA---
>sp|Q9LRH7|ABAMS_PEA Mixed-amyrin synthase OS=Pisum sativum GN=OSCPSM PE=1 SV=1
MWKLKIGDGGDRNIFSTNNFVGRQTWEFDPDAGTSQEKAQVEAARQHFYDNRFEVKACSDLLWRFQILKEKNFKQTIE-SVKIKDEEEISEENVAITLRR
AVHHLSTLQSNDGHWPALNAGPLFYFPPLVFCMYVTGHLDSIFPYEYRKEILRYIYCHQNEDGGWGLHVEGHSIMFCTVLNYICMRILGEGPNGGKEDAC
ARARKWIHDHGSVTHVSSWGKIWLSVLGIFDWCASNPMPPEFWMLPSFLLKHPAKMLCYCRLVYMPMSYLYGKRFVGPITPLILMLREELLTQPYEKVNW
KKTRHLCAKEDLYYPHPLIQDLIWDSLYIFVEPLLTHWPFNKLREKALQTVMKHIHYEDENSRYITIGCVEKVLCILACWVEDPNGDAFKKHLARLPDYL
WVSEDGMTLHSF-GSQTWDASLIIQALLATNLIEDVGPILTKAHEFIKKSQVRDNPSGDFKSYRHISKGSWTFSDKDHGWQVSDCTAESLKCCLLLSMLP
PEIVGEKMEPEMLYDSVNILLSLQGKKGGLPAWEPSEAVEWLELFNPIEFLEEIVVEREYVECTSSAIQALVLFKKLYPEHRKKEVENFIANAVRFLEYK
QTSDGSWYGNWGICFTYGSWFALNGLVAAGKTYDNCAAIRKGVEFLLTTQREDGGWGESHLSSSKYVPLERSQSNIVQTSWAIMGLIHAGQMERDPTPLH
RAVKLIINFQQEEGDWPQQELTGVFMKNCMLQYAMYRDIFPTWALAEYRRRILL---
>sp|P0C8Y0|LUP3_ARATH Camelliol C synthase OS=Arabidopsis thaliana GN=CAMS1 PE=1 SV=1
MWKLKIANGNEPYLFSTNNFLGRQTWEFDPDAGTVEELAAVEEARRKFYDDRFRVKASSDLIWRMQFLKEKKFEQVIP-PAKVEDANNITSEIATNALRK
GVNFLSALQASDGHWPAENAGPLFFLPPLVFCLYVTGHLHEIFTQDHRREVLRYIYCHQNEDGGWGLHIEGNSTMFCTTLNYICMRILGEGPNGGPGNAC
KRARDWILDHGGATYIPSWGKTWLSILGVFDWSGSNPMPPEFWILPSFLPIHPAKMWCYCRLVYMPMSYLYGKRFVGPISPLILQLREEIYLQPYAKINW
NRARHLCAKEDAYCPHPQIQDVIWNCLYIFTEPFLACWPFNKLREKALGVAMKHIHYEDENSRYITIGCVEKALCMLACWVEDPNGIHFKKHLLRISDYL
WIAEDGMKMQSF-GSQLWDSGFALQALVASNLVNEIPDVLRRGYDFLKNSQVRENPSGDFTNYRHISKGSWTFSDRDHGWQASDCTAESFKCCLLLSMIP
PDIVGPKMDPEQLYEAVTILLSLQSKNGGVTAWEPARGQEWLELLNPTEVFADIVVEHEYNECTSSAIQALILFKQLYPNHRTEEINTSIKKAVQYIESI
QMLDGSWYGSWGVCFTYSTWFGLGGLAAAGKTYNNCLAMRKGVHFLLTTQKDNGGWGESYLSCPKYIPSEGERSNLVQTSWAMMGLLHAGQAERDPSPLH
RAAKLLINSQLENGDFPQQEITGAFMKNCLLHYAAYRNIFPVWALAEYRRRVPL---
>sp|B9X0J1|STBOS_STERE Baccharis oxide synthase OS=Stevia rebaudiana PE=1 SV=1
MWRLKIADGNNPYLYSTNNFVGRQTWEFDPNYGTQEERDEVEQARQHFWNNRHQFKATGDVLWRMQFIREKRFKQTIP-QVKIEDGEEISYDKVTATLRR
SVHLLAALQADDGHWPAENTGPMFFIQPLVICLYITGHLDRVFPKEHKKEILRYLYTQQNEDGGWGLHIEGQSIMFGTIMSYVCMRLLGEGPDGGLNGAC
TKARKWILDHGSVLASPSWGKIYLTILGVHEWEGCNPLPPEFWILPSIFPMHPAKMWCYCRLIYMPMSYLYGRRFVGPITPLVLQLREELYSQSYNDIKW
KSTRHLVVKEDLHYPHPWLQDLMWDGLYIFTEPLLTRWPFSKLREKALKTTINHIHYEDENSRYITIGAVEKSLCMLACWDEDPDGVCFKKHLARIPDYI
WVSEDGLKMQSF-GSQLWDASLAIQALLATDLNHDIEPILRKGHDFIKASQVKDNPSGDFKSYRHITKGSWTFSDQDHGWQTSDCTTEGLKCCLLLSKMS
AEIVGEKMQPEQFYDAVNLILSLQCKNGGEAGWEPAGESNWLEFLNPSELFEDIVLEHDSVECTATGMQALVIFKKLYPKHRREEIEKFLKDACGYLEKV
QMQDGSWYGEWGICFTYGTCFALGGMEAIGKTYENCEAIRRAVNFLLTTQRNDGGWGESYRSSPKYVPLEGNRSNLVQTACALMGLIRSKQEERDPTPLH
RAAKLLINSQMENGDFPQEETGGVFKKNCLLHYPMYRNIYTLWALGEYRKKVLP---
>sp|F8WQD0|SHS1_ASTTA Shionone synthase OS=Aster tataricus GN=SHS1 PE=1 SV=1
MWRLKIADGGNPYLYSTNNFIGRQTWEFDPNYGTPEERDEVEQARLHFWNHRHEIKPSGDTLWRMQFIREKKFKQTIP-QVKIEDDEEISYDKVTATMRR
SVHLLEALLADDGHWPAENSGPSFFIQPLVMCLYITGHLNSVFPAEHRKEILRYVYSHQNKDGGWGLHMEGHSIMFGTTLSYICMRLLGEGPDGGLNGAC
TRARKWILDHGGAIANPSWGKVWLSILGVHEWVGCNPLPPEFWLFPSFLPMSPGKMWSYCRLVFMPMSYLYGRRFVGPITPLVLQLRKELYAQPYNDIKW
KSSRHVCAKEDIYYPHPLLQDLMWDSLYILTEPLLTRWPFNKLRKKALATTMRHIHYEDENSRYITIGSVEKILCMLACWDEDPNGVCFKKHLARIPDYI
WVAEDGMKMQTF-GSQVWDASIGIQALLATELTHDIAPILKKGHEFIKASQVRDNPSGDFKSYRHISKGSWTFSDQDHGWQLSDCTTIGLTCCLLLSTMP
PETVGEKMDPEQLKDAVNVILSLQSENGGLAAWEPAGSSNWLEMLNPIEFIEDIVIEHEYVECTGTGMEALVLFKKLYPKHRTKEVESFLTNAARYLDNT
QMPDGSWYGEWGICFTYGTYYALGGLAAIEKTYENCQSIRKAVRFLLKTQGEDGGWGESYRSCAEYIPLDGNRSTVVHTAWAMLGLMHSKQEERDPIPLH
RAAKLLINSQMENGDFPQQDTTGAFKKNCLLHYPMYRNIYTLWALAQYRKKVLR---
>sp|Q8W3Z4|CAS1_BETPL Cycloartenol synthase OS=Betula platyphylla GN=CASBPX1 PE=1 SV=1
MWKLKIGAGGETWLRSLNNHLGRQIWEFHPELG-QEELQQIDDARRRFWERRFERRHSSDLLMRIQFAKENPSAN-IP-QVKIKDTEEVREEAVGMTLRR
AINFYSTIQADDGHWPGDYGGPMFLIPGLVITLSITGTLNAFLSKEHQCEICRYLYNHQNEDGGWGLHIEGPSTMFGTALNYITLRLLGE-PEDGMG-AV
EKARKWILDHGGATAITSWGKMWLSVLGVYEWSGNNPLPPEVWLCPYLLPCHPGRMWCHCRMVYLPMSYLYGKRFVGPITSTIQSLRKELYTVPYHEIDW
NKARNDCAKEDLYYPHPLVQDILWASLYYAYEPIFMYWPAKRLREKALDTVMQHIHYEDENTRYICIGPVNKVLNMLCCWAEDPNSEAFKLHLPRILDYL
WIAEDGMKMQGYNGSQLWDTTFAVQAIISTNIAEEYGQTLRKAHEYIKDSQVLEDCPGDLNFYRHISKGAWPFSTADHGWPISDCTAEGLKAVILLSQFP
SETVGKSVDVKRLYDAVHVILSLQNTDGGFATYELTRSYHWLELINPAETFGDIVIDYPYVECTSAAIQALTLFKKLHPGHRREEIENCIAKAAEFIENI
QASDGSWYGSWGVCFTYAGWFGIKGLVAAGRTYKNCSSIHKACDYLLSKELASGGWGESYLSCQDYTNLKDNRPHIVNTGWAMLALIDAGQAERDPTPLH
RAARILINSQMENGDFPQEEIMGVFNKNCMISYSAYRNIFPIWALGEYRCRVLK---
>sp|A8CDT3|LUPS_BRUGY Lupeol synthase OS=Bruguiera gymnorhiza GN=LUS PE=1 SV=1
MWRLKIAEGGNPYIYSTNNFVGRQTWEFDPEAGTPEERAQVEEARENFWRDRFLIKPSSDLLWRFQFLSEKKFKQRIP-QVKVQDGEEITREIATTALRR
SVHLVSALQASDGHWCAENSGPMFFVPPMVFSLYITGHLNAVFSAEHCKEILRYIYCHPNEDGGWGLHIEGHSAMFSTVLNYNWLGKLGEGRDGGKDNAC
ERARRRILDHGSATAISSWGKTWLAILGVYEWDGCNPMPPEFWAFPTFFPIHPARMLCYCRLTYMAMSYLYGKKFVGPITPLILQLREEIYNEPYDQINW
SRMRHLCAKEDNYYAHTLTQIILWDAIYMLGEPLLKRWPFNKLREKALKITMDHIHYEDENSQYITIGSVEKPLLMLACWHEDPNGDAFKKHLARIPDYV
WLGEDGIKIQSF-GSQVWDTSFVLQALIASNLPSETGPTLEKGHNFIKNSQVTQNPSGDFRRFRHISKGSWTFSDKDHGWQVSDCTAESLKCCLLFSMMP
PELVGEKMGPQRMYDAVNVIISLQSKNGGCSAWEPAGAGSWMEWLNPVEFLADLVIEHEYVECTSSSLQALVLFKKLYPEHRRKEIEIFILNAVRFTEEI
QQPDGSWYGNWGICFLSGTWFGLKGLAAAGKTYYNCTAVRKGVEFLLQTQRDDGGWGESYLSCPKYVPLEGNRSNLVQTALAMMGLILGGQGERDPTPLH
RAAKLLINSQTELGDFPQQELSGCFMRNCMLHYSEYRDIFPTWALAEYCKLFPL---
>sp|E2IUB0|CASS_KALDA Cycloartenol synthase OS=Kalanchoe daigremontiana PE=1 SV=1
MWKLKIAD-ASQWLRSVNNHIGRQIWDFDPALG-PEELAQIEDARDNFARHRFDKKHSADLLMRFQLTKENPQDL-LP-KVNIGKIEDITEDAVTNTLRR
AINFHSTTQAHDGHWPGDYGGPLFLMPGLVITLSITGALNAVLSKEHKKEMCRYLYNHQNEDGGWGLHIEGPSTMFGSVLNYVTLRLLGEDVNGGDG-EI
ERARKWILDHGGATAITSWGKMWLSVLGVFEWCGNNPLPPEMWLFPYYLPVHPGRMWCHCRMVYLPMSYLYGKRFVGPITPTVLSLRKELFTVPYHEIDW
NEARSLCAKEDLYYPHPVVQDILWATLHKVVEPVLLNWPGKKLREKALCSAIEHIHYEDENTRYICIGPVNKVLNMLCCWVEDPNSEAFKLHIPRLYDYL
WIAEDGMKMQGYNGSQLWDTAFSVQAIVATKLVEEFSSTISKAHEFMKNSQVLEDYPGDLSYYRHISKGAWPFSTADHGWPISDCTAEGLKVVLKLSQFP
AELVGAPLSAKLVYNAVNVILSLQNIDGGFATYELTRSYSWMELLNPAETFGDIVIDYPYVECTSAALQSLVLFKKLHPEHRKEEVELCIKKAAAFIEKI
QESDGSWYGSWAVCFTYGTWFGVLGLVAAGRNYKNSPSIRKACDFLLSKQLASGGWGESYLSCQNYTNIPGGRSHVVNTGWAMLALIGAGQAERDPVPLH
RAAKFLIESQLENGDFPQQEIMGVFNKNCMISYAAYRNIFPIWALGEYRCKVLN---
>sp|Q9C5M3|LUP1_ARATH Lupeol synthase 1 OS=Arabidopsis thaliana GN=LUP1 PE=1 SV=1
MWKLKIGKGNDPHLFSSNNFVGRQTWKFDHKAGSPEERAAVEEARRGFLDNRFRVKGCSDLLWRMQFLREKKFEQGIP-QLKATNIEEITYETTTNALRR
GVRYFTALQASDGHWPGEITGPLFFLPPLIFCLYITGHLEEVFDAEHRKEMLRHIYCHQNEDGGWGLHIESKSVMFCTVLNYICLRMLGENPE---QDAC
KRARQWILDRGGVIFIPSWGKFWLSILGVYDWSGTNPTPPELLMLPSFLPIHPGKILCYSRMVSIPMSYLYGKRFVGPITPLILLLREELYLEPYEEINW
KKSRRLYAKEDMYYAHPLVQDLLSDTLQNFVEPLLTRWPLNKLREKALQLTMKHIHYEDENSHYITIGCVEKVLCMLACWVENPNGDYFKKHLARIPDYM
WVAEDGMKMQSF-GCQLWDTGFAIQALLASNLPDETDDALKRGHNYIKASQVRENPSGDFRSYRHISKGAWTFSDRDHGWQVSDCTAEALKCCLLLSMMS
ADIVGQKIDDEQLYDSVNLLLSLQSGNGGVNAWEPSRAYKWLELLNPTEFMANTMVEREFVECTSSVIQALDLFRKLYPDHRKKEINRSIEKAVQFIQDN
QTPDGSWYGNWGVCFIYATWFALGGLAAAGETYNDCLAMRNGVHFLLTTQRDDGGWGESYLSCSEYIPSEGERSNLVQTSWAMMALIHTGQAERDLIPLH
RAAKLIINSQLENGDFPQQEIVGAFMNTCMLHYATYRNTFPLWALAEYRKVVFI---
>sp|Q948R6|IMFS_LUFAE Isomultiflorenol synthase OS=Luffa aegyptiaca GN=IMS1 PE=1 SV=1
MWRLKVADGGDPYIYSMNNFIGRQIWEFDPNAGTPEERAEIERLRHHFTKNRHKGFPSADLLWRVQLLREKNFKQSIP-AVKVGDGEEISYEMALDAMRR
GAHFLAAIQASDGHWPSETSGPLFYVCPLLICMYIMGFMDKVFSPEHKKEMMRYIYNHQNEDGGWGLHVGGHSNMFCTTFNYISLRLLGEEPD---VEAV
CKARNWIHDHDGVTSILSWGKTWLSILNVFDWSASNPMPPEYWMLPTWVPIHPSNMMCYTRITYMPMSYLYGKRFQAPLTPLVLQLRDELHTQPYDQINW
RKVRHMCATEDLYFPHPFVQDLLWDTLYLLSEPLMTRWPFNKLRQKALNETMRHIHYEDENSRYITIGCVEKPLCMLACWVEDPNSEYVKKHLARIPDYL
WMAEDGMKMQSF-GSQSWDAALAMQALLSCNITREIGSVLNSGHDFIKNSQVRNNPPGDYKSFRYMSKGSWTFSDCDHGWQVSDCTAENLKCCLLLSLLP
PDIVGEKMEPERFYDAVNVILNMQSKNGGLPAWEPASSYYWMEWLNPVEFLEDLIIEHQHVECTSSALQAILLFRKQYPGHRRKEINNFINKAVQFLQDI
QLPDGSWYGNWGICYTYGTWFALKALSMAGKTYENCEAVRKGANFLRKIQNPEGGFGESYLSCPYYIPLDGKRSNLVQTAWGMMGLICAGQADVDPTPIH
RAAKLLINSQTEDGDFPQEEITGEFFKNCTLHFAAFREVFPVMALGEYCNKVPL---
>sp|Q6BE24|CUCS_CUCPE Cucurbitadienol synthase OS=Cucurbita pepo GN=CPQ PE=1 SV=1
MWRLKVGA-EEKWVKSVSNHLGRQVWEFCAAAD-PHQLLQIQNARNHFHHNRFHRKQSSDLFLAIQYEKEIAKAK-GG-AVKVKEGEEVGKEAVKSTLER
ALGFYSAVQTRDGNWASDLGGPLFLLPGLVIALHVTGVLNSVLSKHHRVEMCRYLYNHQNEDGGWGLHIEGTSTMFGSALNYVALRLLGEDADGGDGGAM
TKARAWILERGGATAITSWGKLWLSVLGVYEWSGNNPLPPEFWLLPYSLPFHPGRMWCHCRMVYLPMSYLYGKRFVGPITPKVLSLRQELYTIPYHEIDW
NKSRNTCAKEDLYYPHPKMQDILWGSIYHVYEPLFTRWPGKRLREKALQAAMKHIHYEDENSRYICLGPVNKVLNMLCCWVEDPYSDAFKLHLQRVHDYL
WVAEDGMRMQGYNGSQLWDTAFSIQAIVATKLVDSYAPTLRKAHDFVKDSQIQEDCPGDPNVFRHIHKGAWPLSTRDHGWLISDCTAEGLKASLMLSKLP
STMVGEPLEKNRLCDAVNVLLSLQNDNGGFASYELTRSYPWLELINPAETFGDIVIDYPYVECTAATMEALTLFKKLHPGHRTKEIDTAIGKAANFLEKM
QRADGSWYGCWGVCFTYAGWFGIKGLVAAGRTYNSCLAIRKACEFLLSKELPGGGWGESYLSCQNYTNLEGNKPHLVNTAWVLMALIEAGQGERDPAPLH
RAARLLMNSQLENGDFVQQEIMGVFNKNCMITYAAYRNIFPIWALGEYCHRVLT---
>sp|Q9FZI2|LUP5_ARATH Lupeol synthase 5 OS=Arabidopsis thaliana GN=LUP5 PE=2 SV=1
MWRLKVGEGKDPYLFSSNNFVGRQTWEFDPKAGTREERTAVEEARRSFFDNRSRVKPSSDLLWKMQFLKEAKFEQVIP-PVKIDGGEAITYEKATNALRR
GVAFLSALQASDGHWPGEFTGPLCMLPPLVFCLYITGHLEEVFDAEHRKEMLRYIYCHQNEDGGWGFHIESKSIMFTTTLNYICLRILGVGPDGGLENAC
KRARQWILSHGGVIYIPCWGKVWLSVLGIYDWSGVNPMPPEIWLLPYFLPIHLGKAFSYTRITYMPISYLYGKKFVGQITPLIMQLREELHLQPYEEINW
NKARHLCAKEDKYYPHPLVQDLIWDALHTFVEPLLASWPINKLRKKALQVAMKHIHYEDENSHYITIGCIEKNLCMLACWIDNPDGNHFKKHLSRIPDMM
WVAEDGMKMQCF-GSQLWMTGFAVQALLASDPRDETYDVLRRAHDYIKKSQVRDNPSGDFKSYRHISKGGWTLSDRDHGWQVSDCTAEAAKCCMLLSTMP
TDITGEKINLEQLYDSVNLMLSLQSENGGFTAWEPVRAYKWMELMNPTDLFANAMTEREYTECTSAVLQALVIFNQLYPDHRTKEITKSIEKAVQFIESK
QLRDGSWYGSWGICFTYGTWFALCGLAAIGKTYNNCLSMRDGVHFLLNIQNEDGGWGESYMSCPEYIPLEGNRSNVVQTAWAMMALIHAGQAKRDLIPLH
SAAKFIITSQLENGDFPQQELLGASMSTCMLHYSTYKDIFPPWALAEYRKAAFI---
>sp|Q6BE23|OXSC_CUCPE Probable oxidosqualene cyclase OS=Cucurbita pepo GN=CPR PE=2 SV=1
MWTLKFSK---GWETSDNAHLGRQFWEFDPNLQSLEEQARVHNVCNDFYTHRFQAKHSSDLLMRLQLKKANGSVKLPT-QVKLRSEEEMSEEAVETTLRR
AIRFYSTMQTQDGFWPGDYAGPLFLLPGLVIGLSVTKALDTVLSRHHQQEMRRYLYNHQNEDGGWGLHIEGNSTMLCTALSYVSLRLLGEEMDGCDG-AL
RQARRWILDRGGATSIPSWGKLWLSVLGVYEWEGNNPLPPEIWLLPYFLPLHPGRMWCHSRMVYLPMSYLYGKRFVGPISPIITSLRQELYTSPYHMIDW
NLSRSLCAKEDLYTPHSKIQDMLWDSIHKLGEPLLKKWPLSKLRQKALDFVIKHIHYEDENTHYLCLGPVSKVVNMVCCWDEDPNSEAFTRHISRIKDYL
WLAEDGMKMQGYHGSQLWDVAFAIQAIVATDLVEEYGSVLKKAHDFVKNSQVRRNGFGDPSDYRHNSKGGWPFSTPDNAWPVSDCTSEALKVAIMMSQMP
PTMVGEPMDIRKLYDAVDLILSLQNSNGGFASYELTRSHPWLETLNPAEIFGDVMIDYQYVECSSAAIERLKAFMKLHPSYRKKEIQACMAKAADFIETI
QQPDGSWYGSWGICYTYGTWFGIKGLVACGRTYENSKTLRKATHFLLSKQLKSGGWGESYLSAHNYTDLKNGKSHIVNTSWALLALIKAGQAQRDPSPLH
QAATVLINSQLDNGDFPQQEIIGVFNKSCTISYSAYRNIFPIWALGEYQLKVLK---
>sp|A8C981|TARS_RHISY Taraxerol synthase OS=Rhizophora stylosa GN=M2 PE=2 SV=1
VWRLKIGEGANPYLTSTNNFVGRQTWVFEPDGGTPEERDQVEEARQNYFKNRFRVRPCSDLLWQMQFLREKNFRQKIP-QVKVRDGEEINYETVTNAIRR
SAHYLSATQSSDGFWPADASAPVFYLAPWVIGLYVIGHLNTVFPAEHQKEILRYIYCHQNEDGGWGLHYEDGGTMFGTAFNYVCMRILGEGPGGGRDNAC
ERARKGILDHGGVTYIPSGGKTWLAMLGVFDWSGCNPMPPEFWMLPPFFPMHPAQMWCYCRIVYMPMSYLYGRRFVGPITPLVQQLREELHTQPFHEIEW
SKARHLCAKEDLFHRRPWIQELFWDCLHTFAEPLLTRWPLNNFREKALKITMEHVHYDDKASHYINPGSVEKVICMVACWVEDPSGEPFQRHLARISDYV
WIAEDGMRITGI-GSQTWDAALSIQALIACNLIEEMGPTLKKGYDFLKNSQAKDNPPGDFKRYRHFGKGAWAFSSQDYGVIALDCTAESLMCCLHFSMMP
PEIVGEKLEPEKLYLAVDFILSLQSKNGGLTCWEPARGGKWLEVLNPLEFFENIVVEHEYVEVTASAINALVMFKKRYPGYREKEIEHFISKAVHYLIQT
QFPNGPWYGVWGICFMYGTYFALKGLAAAGNTYANCPAIPKAVDFLLKTQCQDGGWGESYLSGTTYTPLEGNRSNLVQTAWALMGLIHSGQAERDPTPLH
RSAKLLINSQTSDGDFPQQDSTGLLKGSCAMHYAAYRNIFPLWALAAYRTHVLG---
>sp|H2KWF1|PAKSY_ORYSJ Parkeol synthase OS=Oryza sativa subsp. japonica GN=Os11g0189600 PE=1 SV=1
MWRLKVSE-GSPWLRSVNNLLGRQVWEFDPDLG-PEERADVEKARREFAEHRFERKHSSDLLMRMQFAKENCQLD-LL-AVKRGEHEDVMGEAVWSSLKR
AISRVCNLQAHDGHWPGDYAGLMFFLPGLIITLHVSGVLNTVLSSEHQKEMRRYIYNHQNEDGGWGLHIEGHSTMLGSSLNYVALRLLGEGPNGGDG-CI
ENGRNWILDHGGATFTTSWGKFWLSVLGVFDWSGNNPVPPELLLLPYQLPFHPGRMSSYIRMVFIPMSYIYGKRFVGPVTPVVLELRSELYNDPYDEIDW
NKARTQCAKEDMYYPRSSKLDMFWSFLHKFIEPVLLRWPGRKLREKALATSMRNVHYEDECTRYICFGGVPKALNILACWIEDPSSEAFKCHIARVYDYL
WIAEDGMKMQIYDGSQVWDAGLTVEALVATDLVKELGPTLKRAHSFLKNSQLLDNCPRDFNRYRHISKGGWTFTTADDGWQVSDCTATALKACLLLSRIS
PEIVGEPLEIDAQYDAVNCLMSLMNDNGGFSAFELVRSNTWLEHINPTEAFGRVMIEYPYVECTSSSIQCLALFKKLHPGHRKEEVENCISKGANFIESS
QRSDGSWYGSWGICFTYATWFAVTGLVSAGRTLGNSATVRKACDFLLSKQLPSGGWGESYLSCHDYTNLKGNRPHGTHTAWAMIALIDAGQAERDPVPLH
RAAKALLNLQLEDGEFPQQEIVGVFLQTAMISYSQYRNIFPIMALTGYRRRVLL---
>sp|Q08IT1|DADIS_PANGI Dammarenediol II synthase OS=Panax ginseng GN=PNA PE=1 SV=1
MWKQKGAQ-GDPYLYSTNNFVGRQYWEFQPDAGTPEEREEVEKARKDYVNNKHGIHPCSDMLMRRQLIKESGILLSIP-PLRLDENEQVNYDAVTTAVKK
ALRLNRAIQAHDGHWPAENAGSLLYTPPLIIALYISGTIDTILTKQHKKELIRFVYNHQNEDGGWGSYIEGHSTMIGSVLSYVMLRLLGEGLAESGNGAV
ERGRKWILDHGGAAGIPSWGKTYLAVLGVYEWEGCNPLPPEFWLFPSSFPFHPAKMWIYCRCTYMPMSYLYGKRYHGPITDLVLSLRQEIYNIPYEQIKW
NQQRHNCCKEDLYYPHTLVQDLVWDGLHYFSEPFLKRWPFNKLRKRGLKRVVELMRYGATETRFITTGNGEKALQIMSWWAEDPNGDEFKHHLARIPDFL
WIAEDGMTVQSF-GSQLWDCILATQAIIATNMVEEYGDSLKKAHFFIKESQIKENPRGDFLKCRQFTKGAWTFSDQDHGCVVSDCTAEALKCLLLLSQMP
QDIVGEKPEVERLYEAVNVLLYLQSRSGGFAVWEPPVPKPYLEMLNPSEIFADIVVEREHIECTASVIKGLMAFKCLHPGHRQKEIEDSVAKAIRYLERN
QMPDGSWYGFWGICFLYGTFFTLSGFASAGRTYDNSEAVRKGVKFFLSTQNEEGGWGESLESCPSFTPLKGNRTNLVQTSWAMLGLMFGGQAERDPTPLH
RAAKLLINAQMDNGDFPQQEITGVYCKNSMLHYAEYRNIFPLWALGEYRKRVWL---
>sp|Q1G1A4|LAS1_ARATH Lanosterol synthase OS=Arabidopsis thaliana GN=LAS1 PE=2 SV=1
MWRLKLSE---GDEESVNQHVGRQFWEYDNQFGSE-ERHHINHLRSNFTLNRFSSKHSSDLLYRFQCWKEKGKMERLP-QVKVKEERLINEEVVNVTLRR
SLRFYSILQSQDGFWPGDYGGPLFLLPALVIGLYVTEVLDGTLTAQHQIEIRRYLYNHQNKDGGWGLHVEGNSTMFCTVLSYVALRLMGEELDGGDG-AM
ESARSWIHHHGGATFIPSWGKFWLSVLGAYEWSGNNPLPPELWLLPYSLPFHPGRMWCHCRMVYLPMSYLYGRRFVCRTNGTILSLRRELYTIPYHHIDW
DTARNQCAKEDLYYPHPKIQDVLWSCLNKFGEPLLERWPLNNLRNHALQTVMQHIHYEDQNSHYICIGPVNKVLNMLCCWVESSNSEAFKSHLSRIKDYL
WVAEDGMKMQGYNGSQLWDVTLAVQAILATNLVDDYGLMLKKAHNYIKNTQIRKDTSGDPGLYRHPCKGGWGFSTGDNPWPVSDCTAEALKAALLLSQMP
VNLVGEPMPEEHLVDAVNFILSLQNKNGGFASYELTRSYPELEVINPSETFGDIIIDYQYVECTSAAIQGLVLFTTLNSSYKRKEIVGSINKAVEFIEKT
QLPDGSWYGSWGVCFTYATWFGIKGMLASGKTYESSLCIRKACGFLLSKQLCCGGWGESYLSCQNYTNLPGNKSHIVNTSWALLALIEAGQASRDPMPLH
RGAKSLINSQMEDGDYPQQEILGVFNRNCMISYSAYRNIFPIWALGEYRKLMLS---
>sp|Q9LVY2|PEN3_ARATH Tirucalladienol synthase OS=Arabidopsis thaliana GN=PEN3 PE=1 SV=2
MWRLRIGAKADPHLCTTNNFLGRQIWEFDANAGSPAELSEVDQARQNFSNNRSQYKACADLLWRMQFLREKNFEQKIP-RVRIEDAKKITFEDAKNTLRR
GIHYMAALQSDDGHWPSENAGCIFFNAPFVICLYITGHLDKVFSEEHRKEMLRYMYNHQNDDGGWGIDVESHSFMFCTVINYICLRIFGVDPDHD-ESAC
ARARKWIIDHGGATYTPLFGKAWLSVLGVYEWSGCKPIPPEFWFFPSYFPINGGTLWIYLRDTFMAMSYLYGKKFVAKPTPLILQLREELYPQPYAEIVW
SQARSRCAKEDLYYPQSLVQDLFWKLVHMFSENILNRWPFNKLREKAIRTAMELIHYHDEATRYITGGAVPKVFHMLACWVEDPESDYFKKHLARVSHFI
WIAEDGLKIQTF-GSQIWDTAFVLQVMLAADVDDEIRPTLIKGYSYLRKSQFTENPPGDYINFRDISKGGWGYSDKDQGWPVSDCISESLECCLIFESMS
SEFIGEKMEVERLYDAVNMLLYMQSRNGGISIWEAASGKKWLEWLSPIEFIEDTILEHEYLECTGSAIVVLARFMKQFPGHRTEEVKKFITKGVKYIESL
QIADGSWYGNWGICFIYGTFFAVRGLVAAGNTYDNCEAIRRAVRFLLDIQNGEGGWGESFLSCPNYIPLEGNKTDVVNTGQALMVLIMGGQMDRDPLPVH
RAAKVLINSQMDNGDFPQQEIRGVYKMNVMLNFPTFRNSFTLWALTHYTKAIRL---
>sp|Q9SYN1|PEN6_ARATH Seco-amyrin synthase OS=Arabidopsis thaliana GN=PEN6 PE=1 SV=1
MWRLKIGAKGETHLFTTNNYTGRQTWEFDADACSPEELAEVDEARQNFSINRSRFKISADLLWRMQFLREKKFEQKIP-RVEIGDAENITYKDAKTALRR
GILYFKALQAEDGHWPAENSGCLFFEAPFVICLYITGHLEKILTLEHRKELLRYMYNHQNEDGGWGIHVEGQSAMFCTVINYICLRILGVEADLDKGSGC
ARARKWILDHGGATYTPLIGKAWLSILGVYDWSGCKPIPPEVWMLPTFSPFNGGTLWIYFRDIFMGVSYLYGKKFVATPTPLILQLREELYPQPYDKILW
SQARNQCAKEDLYYPQSFLQEMFWKCVHILSENILNRWPCNKLRQKALRTTMELLHYQDEASRYFTGGCVPKPFHMLACWVEDPDGDYFKKHLARVPDYI
WIGEDGLKIQSF-GSQLWDTAFSLQVMLAYDDDDEIRSTLIKGYSFLNKSQLTQNPPGDHRKLKDIAKGGWTFSDQDQGWPVSDCTAESLECCLVFGSMP
SELIGEKMDVERLYDAVNLLLYFQSKNGGITVWEAARGRTWLEWLSPVEFMEDTIVEHEYVECTGSAIVALARFLKEFPEHRREEVEKFIKNAVKYIESF
QMPDGSWYGNWGVCFMYGTFFAVRGLVAAGKTYQNCEPIRKAVQFILETQNVEGGWGESYLSCPNYTLLEGNRTNVVNTGQALMVLIMGGQMERDPLPVH
RAAKVLINSQLDNGDFPQEEIMGVFKMNVMVHYATYRNIFTLWALTYYTKALRV---
>sp|O23390|BARS1_ARATH Baruol synthase OS=Arabidopsis thaliana GN=BARS1 PE=1 SV=2
MWRLRIGAKANTHLFTTNNYVGRQIWEFDANAGSPEELAEVEEARRNFSNNRSRFKASADLLWRMQFLREKKFEQKIP-RVIVEDAEKITYEDAKTALRR
GLLYFTALQADDGHWPAENAGSIFFNAPFVICLYITGHLEKIFTHEHRVELLRYMYNHQNEDGGWGLHVESPSNMFCSVINYICLRILGVEAGHDKGSAC
ARARKWILDHGGATYSPLIGKAWLSVLGVYDWSGCKPIPPEFWFLPSFFPVNGGTLWIYLRDIFMGLSYLYGKNFVATSTPLILQLREEIYPEPYTNISW
RQARNRCAKEDLYYPQSFLQDLFWKGVHVFSENILNRWPFNNLRQRALRTTMELVHYHDEATRYITGGSVPKVFHMLACWVEDPESDYFKKHLARVPDFI
WIGEDGLKIQSF-GSQVWDTALSLHVFIDGDVDEEIRSTLLKGYDYLEKSQVTENPPGDYMKFRHMAKGGWTFSDQDQGWPVSDCTAESLECCLFFESMS
SEFIGKKMDVEKLYDAVDFLLYLQSDNGGITAWQPADGKL-------VEFIEDAVVEHEYVECTGSAIVALAQFNKQFPGYKKEEVERFITKGVKYIEDL
QMVDGSWYGNWGVCFIYGTFFAVRGLVAAGKCYNNCEAIRRAVRFILDTQNTEGGWGESYLSCPRYIPLIGNKTNVVNTGQALMVLIMGNQMKRDPLPVH
RAAKVLINSQMDNGDFPQQEIMGVFKMNVMLHFPTYRNMFTLWALTHYTKALRG---
>sp|Q9FI37|PEN4_ARATH Thalianol synthase OS=Arabidopsis thaliana GN=THAS1 PE=1 SV=2
MWRLRTGPKADTHLFTTNNYAGRQIWEFDANAGSPQEIAEVEDARHKFSDNTSRFKTTADLLWRMQFLREKKFEQKIP-RVIIEDARKIKYEDAKTALKR
GLLYFTALQADDGHWPAENSGPNFYTPPFLICLYITGHLEKIFTPEHVKELLRHIYNMQNEDGGWGLHVESHSVMFCTVINYVCLRIVGEEVGHDQRNGC
AKAHKWIMDHGGATYTPLIGKALLSVLGVYDWSGCNPIPPEFWLLPSSFPVNGGTLWIYLRDTFMGLSYLYGKKFVAPPTPLILQLREELYPEPYAKINW
TQTRNRCGKEDLYYPRSFLQDLFWKSVHMFSESILDRWPLNKLRQRALQSTMALIHYHDESTRYITGGCLPKAFHMLACWIEDPKSDYFKKHLARVREYI
WIGEDGLKIQSF-GSQLWDTALSLHALLDGDVDDEIKTTLVKGYDYLKKSQITENPRGDHFKFRHKTKGGWTFSDQDQGWPVSDCTAESLECCLFFESMP
SELIGKKMDVEKLYDAVDYLLYLQSDNGGIAAWQPVEGKAWLEWLSPVEFLEDTIVEYEYVECTGSAIAALTQFNKQFPGYKNVEVKRFITKAAKYIEDM
QTVDGSWYGNWGVCFIYGTFFAVRGLVAAGKTYSNCEAIRKAVRFLLDTQNPEGGWGESFLSCPSYTPLKGNSTNVVQTAQALMVLIMGDQMERDPLPVH
RAAQVLINSQLDNGDFPQQEIMGTFMRTVMLHFPTYRNTFSLWALTHYTHALRR---
>sp|Q9FR95|PEN1_ARATH Arabidiol synthase OS=Arabidopsis thaliana GN=PEN1 PE=1 SV=1
MWRLRIGAKADTHLFTTNNYVGRQIWEFDANAGSPQELAEVEEARRNFSNNRSHYKASADLLWRMQFLREKGFEQKIP-RVRVEDAAKIRYEDAKTALKR
GLHYFTALQADDGHWPADNSGPNFFIAPLVICLYITGHLEKIFTVEHRIELIRYMYNHQNEDGGWGLHVESPSIMFCTVINYICLRIVGVEAGHDQGSTC
TKARKWILDHGGATYTPLIGKACLSVLGVYDWSGCKPMPPEFWFLPSSFPINGGTLWIYLRDIFMGLSYLYGKKFVATPTPLILQLQEELYPEPYTKINW
RLTRNRCAKEDLCYPSSFLQDLFWKGVHIFSESILNRWPFNKLRQAALRTTMKLLHYQDEANRYITGGSVPKAFHMLACWVEDPEGEYFKKHLARVSDFI
WIGEDGLKIQSF-GSQLWDTVMSLHFLLDGDVDDEIRSTLVKGYDYLKKSQVTENPPSDHIKFRHISKGGWTFSDKDQGWPVSDCTAESLKCCLLFERMP
SEFVGQKMDVEKLFDAVDFLLYLQSDNGGITAWEPADGKTWLEWFSPVEFVQDTVIEHEYVECTGSAIVALTQFSKQFPEFRKKEVERFITNGVKYIEDL
QMKDGSWCGNWGVCFIYGTLFAVRGLVAAGKTFHNCEPIRRAVRFLLDTQNQEGGWGESYLSCLRYTPLAGNKTNIVSTGQALMVLIMGGQMERDPLPVH
RAAKVVINLQLDNGDFPQQEVMGVFNMNVLLHYPTYRNIYSLWALTLYTQALRR---
>sp|Q2R712|ACBSY_ORYSJ Achilleol B synthase OS=Oryza sativa subsp. japonica GN=Os11g0285000 PE=1 SV=1
MWRLKIAAGSSPLLHTGNGFLGRAVWEFDPDAGTPEERAEVARLRRDFTRHRFQRKESQDLLMRMQYAKLGHLQPDLS-AVIVEDNQNVTEETILSSLRR
ALNQYSTLQAHDGHWPGDYSGILFIMPLLIFSMHVTGTLDVVLSLEHKREICRYIYNHQNEDGGWGTQVLGQSTMFGSCLNYATLKLLGEALHNN--DAL
AQGRMWILSHGSATAAPQWAKIWLSVIGVYDWSGNKAIIPELWMVPHFLPIHPARFWCFVRMIYMSMAYLYGKKFVGPITPTILEIREELYNIPYSEIDW
KKARDCCAKEDLRYPCSWIQDIVWTYLNKYVDPMFNVWPFNKLREISLRNLMKHIYYEDENTKYIGLCPINKALNMICCWIEDPNSDAFKRHLPRIYDFL
WLAEDGMKAQVYDGCQTWETAFIVQAICSTGLVDEFSTTLEKAYGFLKNSQVLHDLPN-GKSYRHRSKGSWTLSTADNGWSVPDCTGETLQALLGLSKIS
PKLVGDPIKEKSLYDAVDCLLSFSNKDGTFSSYECTRTASWTEILNPSESFRNIVVDYPHVECTSSAIQGLISFTELYPGYRGVEIESCIKNAVMFIENK
QQNDGSWYGTWGICFTYGAFFAIRGLIAAGRNYENSQAIRNGCKFLLSKQLSAGGWGEHYSSSEIYVD--SGSPHAVNTSLAMLALLYSGQIERDPTPLY
RAAKQLISMQLETGEFPQQEHVGCFNSSLYFNYPNYRNLYPIWALGEFWHRLVA---
>sp|Q9FJV8|PEN5_ARATH Marneral synthase OS=Arabidopsis thaliana GN=MRN1 PE=1 SV=1
MWRLRIGAEADPHLFTTNNFAGRQIWEFDANGGSPEELAEVEEARLNFANNKSRFKASPDLFWRRQFLREKKFEQKIP-RVRIEDAEKITYEDAKTALRR
GVLYYAACQANDGHWPSEVSGSMFLDAPFVICLYITGHLEKIFTLEHVKELLRYMYNTQNEDGGWGLDVESHSVMFCTVLNYICLRILGVEPDHDQKSAC
ARARKWILDHGGATYAPMVAKAWLSVLGVYDWSGCKPLPPEIWMLPSFSPINGGTLWIYIRDLLMGMSYLYGKKFVATPTALILQLREELYPQPYSKIIW
SKARNRCAKEDLLYPKSFGQDLFWEGVHMLSENIINRWPLNKFRQRALRTTMELVHYHDETTHYITGACVAKPFHMLACWVEDPDGDYFKKHLARVPDFI
WIAEDGLKFQLM-GMQSWNAALSLQVMLAANMDDEIRSTLIKGYDFLKQSQISENPQGDHLKFRDITKGGWTFQDREQGLPISDGTAESIECCIHFHRMP
SEFIGEKMDVEKLYDAVNFLIYLQSDNGGMPVWEPAPGKKWLEWLSPVEHVENTVVEQEYLECTGSVIAGLVCFKKEFPDHRPKEIEKLIKKGLKYIEDL
QMPDGSWYGNWGVCFTYGTLFAVRGLAAAGKTFGNSEAIRRAVQFILNTQNAEGGWGESALSCPNYIPSKGNVTNVVNTGQAMMVLLIGGQMERDPSPVH
RAAKVLINSQLDIGDFPQQERRGIY-MNMLLHYPTYRNMFSLWALALYTNALRL---
>sp|Q9LS68|PEN7_ARATH Putative pentacyclic triterpene synthase 7 OS=Arabidopsis thaliana GN=PEN7 PE=5 SV=3
MWKLRIGAKADPHLCTTNNYLGRQIWEFDTNACSPEELFEVEKARRNFSDNRSQYKASADLLWRMQFLREKKFKQNIP-RVKIEDAEKITYEEANMTLRR
GIHYMAALQSDDGHWPAENSGCMFFNAPFVICLYITGHLDTIFSQEHRKEMLRYIPIIKNDDGGWGLDVESHSSMFCTVLNYICLRIMEVDPDHDKKSAC
ARARKWIIDRGGATYTPLFGKACLSVLGVYEWSGCKPIPPEFWLFPSYFPINGGTVWIYFRDTFMALSYLYGKKFVATPTPLILQLRQELYPQTYADIVW
SQARNRCAKEDLYYPQTFVQDLFWKSVHMFSENILNRWPFKKLRERAIRRALELIHYHDEATQYITGGGVPKVFHMLACWAEGPESGYFKKHLARVSGFI
WISEDGLKIQSF-GSQIWDTVLLLKVMLAADIDDEIRSMLIKGYSFLRKSQLIENPPGYYIKFRDISKGGWGFSDKDQGWPASDCTSESLECCLIFESMP
SNFIDEKMDVERLYDAVNMLLYLQSENGGKAVWERASGKKWLEWLSPIEFMEETILEHEYVECTGSAVVVLTRFMKQFPRHRTKEIETFIAKAVKYIESL
QMADGSWYGNWGVCFIYATFFAVRGLVAAGKTYQSYEPIRRAVQFLLKIQNDEGGWGESFLSCPGYISLEGNKTNVVNTGQAMMVLIMSGQMERDPLPVH
RAAKVLINSQMENGDFPQQELRGVYKMNVLLHYPTYRNIFSLWALTYYTKALRL---
>sp|Q55D85|CAS1_DICDI Cycloartenol synthase OS=Dictyostelium discoideum GN=cas1 PE=1 SV=1
NWSLKV-------------DRGRQTWEYSQKEA-----T--------DVDIH------------LLRL-----KEPGT-HCP-EGCDLNRAKTPQQAIKK
AFQYFSKVQTEDGHWAGDYGGPMFLLPGLVITCYVTGY---QLPESTQREIIRYLFNRQNPDGGWGLHIEAHSDIFGTTLQYVSLRLLGVPADHP---SV
VKARTFLLQNGGATGIPSWGKFWLATLNAYDWNGLNPIPIEFWLLPYNLPIAPGRWWCHCRMVYLPMSYIYAKKTTGPLTDLVKDLRREIYCQEYEKINW
SEQRNNISKLDMYYEHTSLLNVINGSLNAYEK-VH-----SKWRDKAIDYTFDHIRYEDEQTKYIDIGPVNKTVNMLCVWREGK-SPAFYKHADRLKDYL
WLSFDGMKMQGYNGSQLWDTAFTIQAFMESGIANQFQDCMKLAGHYLDISQVPEDARD-MKHHRHYSKGAWPFSTVDHGWPISDCTAEGIKSALALRS--
L-PFIEPISLDRIADGINVLLTLQNGDGGWASYENTRGPKWLEKFNPSEVFQNIMIDYSYVECSAACIQAMSAFRKHAPNHPIKEINRSIARGVKFIKSI
QRQDGSWLGSWGICFTYGTWFGIEGLVASGEPL--SPSIVKACKFLASKQRADGGWGESFKSNVTYVQHE--TSQVVNTGWALLSLMSAKYPDR--ECIE
RGIKFLIQRQYPNGDFPQESIIGVFNFNCMISYSNYKNIFPLWALSRYNQLYLK---
>sp|Q8BLN5|ERG7_MOUSE Lanosterol synthase OS=Mus musculus GN=Lss PE=2 SV=2
RWRLQN-------------ELGRQRWTYYQDDP-----GR----EQTGLEAH------------SLGL-----DTRS------YFTDLPKAQTAHEGALN
GVTFYAKLQAEDGHWAGDYGGPLFLLPGLLITCHISHI---SLPAGYREEMVRYLRSVQLPDGGWGLHIEDKSTVFGTALNYVALRILGIGPDDP---DL
VRARNVLHKKGGAVAIPSWGKFWLAVLNVYSWEGLNTLFPEMWLFPEWVPAHPSTLWCHCRQVYLPMSYCYATRLSASEDPLVQSLRQELYVQDYASIDW
PAQRNNVSPDEMYTPHSWLLHVVYGLLNLYER-FH-----STSRKWAVQMLYEHIAADDCFTKCISIGPISKTINMLVRWVDGPSSPAFQEHVSRIKDYL
WLGLDGMKMQGTNGSQIWDTSFAIQALLEAGAHPEFLPCLQKAHEFLRLSQVPENCPD-YQKYRHMRKGGFSFSTLDCGWIVADCTAEGLKAVLLLQNQC
P-SITEHIPRERLCDAVDVLLSLRNADGGFATYEKKRGGYLLELLNPSEVFGDIMIDYTYVECTSAVMQALKHFHEHFPDYRAAEVRETLNQGLDFCRRK
QRADGSWEGSWGVCFTYGTWFGLEAFACMGHTYQDCAEVAQACNFLLSQQMADGGWGEDFESCEQYVQSA--RSQVHSTCWALMGLMAVRHPDI--TAQE
RGIRCLLGKQLPNGDWPQENISGVFNKSCAISYTSYRNIFPIWALGRFSNLYPD---
>sp|P48449|ERG7_HUMAN Lanosterol synthase OS=Homo sapiens GN=LSS PE=1 SV=1
RWRLNC-------------ERGRQTWTYLQERA-----GR----EQTGLEAY------------ALGL-----DTKN------YFKDLPKAHTAFEGALN
GMTFYVGLQAEDGHWTGDYGGPLFLLPGLLITCHVARI---PLPAGYREEIVRYLRSVQLPDGGWGLHIEDKSTVFGTALNYVSLRILGVGPDDP---DL
VRARNILHKKGGAVAIPSWGKFWLAVLNVYSWEGLNTLFPEMWLFPDWAPAHPSTLWCHCRQVYLPMSYCYAVRLSAAEDPLVQSLRQELYVEDFASIDW
LAQRNNVAPDELYTPHSWLLRVVYALLNLYEH-HH-----SAHRQRAVQKLYEHIVADDRFTKSISIGPISKTINMLVRWVDGPASTAFQEHVSRIPDYL
WMGLDGMKMQGTNGSQIWDTAFAIQALLEAGGHPEFSSCLQKAHEFLRLSQVPDNPPD-YQKYRQMRKGGFSFSTLDCGWIVSDCTAEALKAVLLLQEKC
P-HVTEHIPRERLCDAVAVLLNMRNPDGGFATYETKRGGHLLELLNPSEVFGDIMIDYTYVECTSAVMQALKYFHKRFPEHRAAEIRETLTQGLEFCRRQ
QRADGSWEGSWGVCFTYGTWFGLEAFACMGQTYRDCAEVSRACDFLLSRQMADGGWGEDFESCEEYLQSA--QSQIHNTCWAMMGLMAVRHPDI--EAQE
RGVRCLLEKQLPNGDWPQENIAGVFNKSCAISYTSYRNIFPIWALGRFSQLYPE---
>sp|P84466|ERG7_BOVIN Lanosterol synthase OS=Bos taurus GN=LSS PE=1 SV=2
RWRLSN-------------QVGRQTWTYSQEDP-----VR----EQSGLEAH------------LLGL-----DTKS------FFKDLPKAHTACRGALN
GVTFYAALQTEDGHWAGDYGGPLFLLPGLLITCHVANI---PLPAGYREEIIRYLRSVQLPDGGWGLHIEDKSTVFGTALNYVSLRILGVGPDDP---DL
VRARNLLHKKGGAVFIPSWGKFWLAVLNVYSWEGLNTLFPEMWLFPDWMPAHPSTIWCHCRQVYLPMAYCYSTRLSAEEGPLVQSLRQELYLEDYSCIDW
AAHRNSVAPDDLYTPHSWLLHVVYAILNLYER-HH-----STSRQWATQKLYEHIAADDRFTKCISIGPISKTINMLVRWVDGPASAVFQEHVSRIPDYL
WLGLDGMKMQGTNGSQIWDTAFAIQALLEARAQPEFWSCLRKAHEYLRISQVPDNFPD-YQKYRHMSKGGFSFSTLDCGWIVADCTAEALKSILLLQEKC
P-FVSNHVPRERLFDTVAVLLSLRNPDGGFATYETKRGGHLLELLNPSEVFGDIMIDYTYVECTSAVMQALKTFHKQFPDHRAGEIRETLEQGLQFCRQK
QRPDGSWEGSWGVCFTYGAWFGLEAFACMGHTYHNCAEISRACDFLLSRQMADGGWGEDFESCKQYVQSA--QSQIHNTCWALMGLMAVRHPDV--AALE
RGVSYLLEKQLPNGDWPQENISGVFNKSCAISYTSYRNVFPIWTLGRFSRLHPD---
>sp|Q96WJ0|ERG7_PNECA Lanosterol synthase OS=Pneumocystis carinii GN=ERG7 PE=2 SV=1
GWRLIVE------------DTGRQRWKYLKEER-----RE---RPQTYMEKY------------FLGK-----NMDLP-EQPAA-------KTPIESARK
GFSFYKHLQTSDGNWACEYGGVMFLLPGLIIAMYISKI---EFPDEMRIEVIRYLVNHANPDGGWGIHIEGKSTVFGTALNYVVLRILGLGPDHP---VT
MKARIRLNELGGAIGCPQWGKFWLAVLNCYGWEGINPILPEFWMLPEWLPIHPSRWWVHTRAVYLPMGYIYGEKFTAPVDPLIESLREELYTQPYSSINF
SKHRNTTSPVDVYVPHTRFLRVINSILTFYHTIFR-----FSWKDMASKYAYKLIEYENKNTDFLCIGPVNFSIHILAVYKEGPDSYAFKSHKERMADFL
WISKKGMMMNGTNGVQLWDTSFAVQALVESGLAPEFKDHMIKALDFLDKCQIQKNCDD-QQKYRHRRKGAWPFSTRQQGYTVSDCTAEALKAVLLLQNLK
SPKR---VSYDRLKDSVDVILSLQNKDGGFASYELIRGPSWLEFINPAEVFGDIMIEHSYPECTTAAVTALCYFRSLCSHYRGPEINKSVKNAIQFIKES
QRPDGSWYESWAICFTYATMFALESLSCVKDFYENSFHSRRACDFLVNKQEEDGGWSEGYQSCTDWTRHPT-GSQVVQTAWACIGLMYANYPDE--TPIK
RGINLIMSRQQPNGEWKQEAIEGVFNKNCMISYPNYKFNFTIKALGMYSKRYGN---
>sp|Q10231|ERG7_SCHPO Lanosterol synthase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=erg7 PE=2 SV=1
LWRLNID------------SAGGETWEYVT-EA-----EK---RPLTIAEKY------------FLGF-----DLDLP-KRPPA-------KTPLESAEY
GYEFFRRLQLPDGHWASPYEGPMFLICGAVFAFYISQT---PFPKGWAPEIIQYLINHTN-DGGWGIHTEGVSTVFGTSMNYVVLRILGMDAGHP---VA
TRARNRLHELGGAIGCPHWGKFWLATLNCYDWDGVNPIPPELWLLPDWIPFHPGKWWCHVRLVYLPMGYMYGERLKCPKDSLIMQLRKELYVENYDSINF
ADHRNTISDVDLYFPHTQILDRLNWILEKYFTYLR-----PSWKKLGTRRAYELIKIEDQNTDYSCIGPVNAAMNTVCVYHEGPSSKAFQKHIQRLHDFM
WVQPEGMLMRGTNGLQVWETSFTLQALVESGLYEAFKPDIAKALEFLDRQQIRTQYEG---SYRYNSLGAWPFSNITQGYTVSDTTSEALRAVLLVQSLP
DEKL---VDIPRLRLSVDVILGMQNENLGFASYEPARTGEWMELLNPAEVFGNIMVEYSYPECTTSVILALRAFTKYDPGYRRDEIENTIENALEYVVKM
QRPDGSWYGSWAICFTYAAMFATGSLASAGRYYENCPVQKKACEFLLSKQRPDGGWSESYMACVTYTETE--SSLVTQTGWALDALINAKYPDR--KPIE
KGIKFLMASQKSDGSWQQKSMEGIFNKNVAIAYPNYKLYFSIYTLGKFAKQYGN---
>sp|P38604|ERG7_YEAST Lanosterol synthase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ERG7 PE=1 SV=6
LWRLRTD------------ELGRESWEYLTQAA-----ND---PPSTFTQWL------------LQ-------DPKFP-QPHPERNKHSPDFSAFDACHN
GASFFKLLQEDSGIFPCQYKGPMFMTIGYVAVNYIAGI---EIPEHERIELIRYIVNTAHPDGGWGLHSVDKSTVFGTVLNYVILRLLGLPKDHP---VC
AKARSTLLRLGGAIGSPHWGKIWLSALNLYKWEGVNPAPPETWLLPYSLPMHPGRWWVHTRGVYIPVSYLSLVKFSCPMTPLLEELRNEIYTKPFDKINF
SKNRNTVCGVDLYYPHSTTLNIANSLVVFYEKYLR-----NRFYSLSKKKVYDLIKTELQNTDSLCIAPVNQAFCALVTLEEGVDSEAFQRLQYRFKDAL
FHGPQGMTIMGTNGVQTWDCAFAIQYFFVAGLAPEFYNTIVSAYKFLCHAQFDTECVP---GYRDKRKGAWGFSTKTQGYTVADCTAEAIKAIIMVKNSP
VSEVHHMISSERLFEGIDVLLNLQNIYGSFATYEKIKAPLAMETLNPAEVFGNIMVEYPYVECTDSSVLGLTYFHKYFD-YRKEEIRTRIRIAIEFIKKS
QLPDGSWYGSWGICFTYAGMFALEALHTVGETYENSSTVRKGCDFLVSKQMKDGGWGESMKSSELYVDSE--KSLVVQTAWALIALLFAEYPNK--EVID
RGIDLLKNRQEESGEWKFESVEGVFNHSCAIEYPSYRFLFPIKALGMYSRAYET---
>sp|Q4WR16|PDSA_ASPFU Protostadienol synthase A OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) GN=pdsA PE=1 SV=1
RWRLNV-------------DNGRHMWEYLEDEA-----RK---RPQSFLEKY------------WLGL-----PYELP-ARPRA-------TCALEAVEN
GWEFFKRLQTADGHWGCNDDGPLFVTSGMVIARYIVGI---PIDSHMKQEMCRYLLNVVNEDGGWGLFIQSPSTVFGTVMNYCMLRILGLGPEHP---AM
AKARNTLHRLGSARATPTWGKFWLCVLGVYEWEGMVPLPPEPLLVPASLPFNPGKWWVHTRNVYISMSYLYGHRFSMPPNKLVQALRDELYDIPYQQINW
PAQRTNVSAADRLTDPTWIQRSFTSALTMYET-FK-----IPFRRRALNEALFQIETETRNTHYLCIAPVSFASNMLALYAHGRDSHWIRGMRDRFIDPM
WLCREGLAASGTNGTSLWDTALTVQATIDAGLAPENQAILRKALEFIDNSQIREDPLG-VHHYRQPTRGAWPFSTRDQSYAVSDTTAEAVKVIVLLQRIE
GPSR---ISDERLQQAIDLILGMENAGGGFSAYEPVRGPKFLELLNITELYENVMTDNLYPECTSSVIMCLTTFAREYPTYRPRDIQACLSRSIDYLLRS
QYPNGGWFASWGVCFTYATMFALQGLACMGWNESNCAACQRACSFLLQHQNPDGGWGESLDTVRFYLPHPD-GSQVTNTAYAVIGLLAARCGNH--EAIR
RGVAYLVKEQQDTGEWLPGPLEGVFAPPGGMRYPNYKFHFTLMALGRYVAIHGN---
>sp|Q04782|ERG7_CANAL Lanosterol synthase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ERG7 PE=3 SV=1
RWRLRSD------------ALGRETWHYLSECE-----SE---PQSTFVQWL------------LE-------SPDFP-SPPSSDIHTS-----GEAARK
GADFLKLLQ-DNGIFPCQYKGPMFMTIGYVTANYYSKT---EIPEPYRVEMIRYIVNTAHPDGGWGLHSVDKSTCFGTTMNYVCLRLLGMEKDHP---VL
VKARKTLHRLGGAIKNPHWGKAWLSILNLYEWEGVNPAPPELWRLPYWLPIHPAKWWVHTRAIYLPLGYTSANRVQCELDPLLKEIRNEIYVLPYESIKF
GNQRNNVCGVDLYYPHTKILDFANSILSKWEA-VR-----PKWLNWVNKKVYDLIVKEYQNTEYLCIAPVSFAFNMVVTCYEGSESENFKKLQNRMNDVL
FHGPQGMTVMGTNGVQVWDAAFMVQYFFMTGLVPKYHDMIRKSYLFLVRSQFTENCVD---GFRDRRKGAWPFSTKEQGYTVSDCTAEAMKAIIMVRNHA
SADIRDEIKDENLFDAVEVLLQIQNVYGSFSTYEGIKAPLLLEKLNPAEVFNNIMVEYPYVECTDSSVLGLTYFAKYYPDYKPELIQKTISSAIQYILDS
DNIDGSWYGCWGICYTYASMFALEALHTVGLDYESSSAVKKGCDFLISKQLPDGGWSESMKGCETYVNGE--NSLVVQSAWALIGLILGNYPDE--EPIK
RGIQFLMKRQLPTGEWKYEDIEGVFNHSCAIEYPSYRFLFPIKALGLYKNKYGD---
>sp|E4V6I8|PDSA_ARTGP Protostadienol synthase A OS=Arthroderma gypseum (strain ATCC MYA-4604 / CBS 118893) GN=PDSA PE=3 SV=1
RWRLKV-------------HEGRHMWEYVDDVA-----QT---QQQTFAENY------------WLGQ-----EYELP-KMSTP-------IFAQDALDN
GWAFFKRLQTQDGHWGCHDDGPLFVTSGIVISSYICGI---TLPDAMKNEMIRYLLNFVNEDGGWGLWINSPSTVFGTTMNYTMLRILGVPSTHP---AL
LDARDTLLKMGSARALPTWGKFWMCALGAYEWDGMIPLAPEPLLAPGFLPLNPGNWWVHTRNVFVSMSYLFGHRFSAPMTPLIQELREELYDMPYHKIDW
FAQQTNISDYDRLHPPTMLQKGLANALCYYEY-VK-----VPYRRKALDEALFQVEMEVHNTSYLCIAPVSFASNMLVMFAHGANSHWVKGMADRIIDPM
WMCREGMAASGTNGTSVWDTALTVQAALDGGLAPENHNTMLEALKFIEVSQITENPLG-VSQYRQPTKGAWPFSTRDQAYAVSDTTAVTVRAVIQLQALK
SPKL---VSDERLAEAVDLIIGMENKCDGYSAFEPLRGPKALELLNITELYDNVMTESLYPECTSSVLLCLDTFTKAYPHHRPVEIQSIMARCARYLIKA
QFPCGGWLASWGVCFTYATMFALQGLETVGLRESNSETCRNACSFLLQYQNDDGGWGEDLISIREYIQDPA-GSQVTCTAYALMGLISAHCSNR--DALR
RGIRWLMRAQQATGEWLPGSLEGIFACPGGMRYPNYKFHFTLSAIGRYIERYGD---
>sp|P33247|SQHC_ALIAD Squalene--hopene cyclase OS=Alicyclobacillus acidocaldarius subsp. acidocaldarius (strain ATCC 27009 / DSM 446 / JCM 5260 / NBR
-------------------------------------------------------------------------------------EQLVEAPAYARTLDR
AVEYLLSCQKDEGYWWGPLLSNVTMEAEYVLLCHILDR---V-DRDRMEKIRRYLLHEQREDGTWALYPGGPPDLDTTIEAYVALKYIGMSRDEE---PM
QKALRFIQSQGGIESSRVFTRMWLALVGEYPWEKVPMVPPEIMFLGKRMPLNIYEFGSWARATVVALSIVMSRQPVFPLPERAR--VPELYEPPRRRG--
AK---GGG--GW----IF--DALDRALHGYQK--LSVHPF---RRAAEIRALDRQAGDGSW-----GGIQPPWFYALIALILDMTQHAI-KGWEGLELYG
VLDYGGWMFQAS-ISPVWDTGLAVLALRAAGLP-ADHDRLVKAGEWLLDRQI-TVPGD-WAVRPNLKPGGFAFQFDNVYYPDVDDTAVVVWALNTLRLPD
E-----RRRRDAMTKGFRWIVGMQSSNGGWGAYDVDNTSDLPNHIPFCD--FGEVTDPPSEDVTAHVLECFGSFGYDDA-------WKVIRRAVEYLKRE
QKPDGSWFGRWGVNYLYGTGAVVSALKAVGIDTRE-PYIQKALDWVEQHQNPDGGWGEDCRSYEDYAGKG-A-STPSQTAWALMALIAGGRAES--EAAR
RGVQYLVETQRPDGGWDEPYYTGGFPGDFYLGYTMYRHVFPTLALGRYKQAIER---
>sp|P55348|SQHC_RHISN Probable squalene--hopene cyclase OS=Rhizobium sp. (strain NGR234) GN=shc PE=3 SV=1
--------------------------------------------------------------------------------MNKHSRTAIDPAALEMSIAS
ATEALLAYRHADGHWAFELEADSTIPSEYILLRHYLAE---PIDVVLEAKIGNYLRRTQGAHGGWPLVHDGPFDMSASVKSYFALKMIGDSVDAA---HM
VKAREAIRARGGAANSNVLTRFLLALYGVVSWRAVPVLPIEIVLLPIWSPFHLYKISYWARTTIVPLMVLAVLKPRAKNPKGVG--IEELFLKSVGMN--
PKAPHQSW--GW-F-LLF--RGIDGILRVIEP--HLPKKL---RERAIASALARLNGEDGM-----GAIYPSMANIVMMYALGKDDHPARRAIDKLLVI-
--GEEEAYCQPC-LSPVWDTALTCHALQEVGGA-NAVAKAKQGLDWLKPRQVLDVKGD-WAVAPNIRPGGWPFQYNNAHYPDLDDTAVVVMAMDRAQRHA
G---S-KEYATAIARGREWIEGMQSRDGGWAAFDVNNLEYYLNNLPFAD--HGALLDPPTEDVTARCVSMLAQVGEFTQ------RSKAVAEGIAYLRRT
QHAEGSWYGRWGLNYIYGTWSVLCALNAAGIDHQD-PMIRKAVEWLVSIQSWDGGWGEDAISYRLSGYEQ-APSTSSQTAWALLGLMAAGEVEH--PAVA
RGVNYLKNAQTENGLWDEQRYTAGFPRVFYLRYHGYSKFFPLWALARYRNLRST---
>sp|P54924|SQHC_BRADU Squalene--hopene cyclase OS=Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110) GN=shc PE=3 SV
-------------------------------------------------------------------------MDSVN-ATAREASKISESEILESSIAS
ATQGVLGFQQSDGHWVFELEADCTIPAEYVLLRHYLAE---PVDTVLEAKIGNYLRRVQGAHGGWPLVHDGEFDMSASVKAYFALKMIGDSIDAP---HM
VRAREAIHARGGAIHSNVFTRFMLAMFGIVTWRAVPVLPIEIMLLPFWSPFHINKISYWARTTMVPLMVIAALKPRAKNPKGVG--IDELFLRSIGMT--
AKAPHQSM--AW-F-LLF--RSLDAILRVIEP--LFPKSL---RKRAIDTALARLNGEDGM-----GAIYPPMANLVMMYALGKDENPTRRGIDKLLVI-
--GDDEAYCQPC-VSPVWDTTLTAHALLEAGGD-KAVPAAKHGLDWLIPKQELEVKGD-WAVRPDVRPGGWAFQYNNAYYPDLDDTAVVVMSMDRMRREH
G---V-TGYDSAIDRGREWIEGMQSDDGGWAAFDVNNLEYYLNNIPFSD--HGALLDPPTEDVTARCVSMLAQLGETAK------TSKHVADGVAYLRKT
QHPEGSWYGRWGMNFIYGTWSVLCALNMAGVRHDD-PMIRKAADWLASIQNKDGGWGEDAVSYRLKGWEA-APSTASQTAWALLALMAAGEVDH--PAVA
RGVEYLIATQNEKGLWDEQRYTAGFPRVFYLRYHGYSKFFPLWALARYRNLRNT---
>sp|P33990|SQHC_ZYMMO Squalene--hopene cyclase OS=Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) GN=shc PE=3 SV=2
-------------------------------------------------------------------------MT-----VSTSSHHSPLSDDVEPIIQK
ATRALLEKQHQDGHWVFELEADATIPAEYILLKHYLGE---PQDLEIEAKIGRYLRRIQGEHGGWSLFYGGDLDLSATVKAYFALKMIGDSPDAP---HM
LRARNEILARGGAMRANVFTRIQLALFGAMSWEHVPQMPVELMLMPEWFPVHINKMAYWARTVLVPLLVLQALKPVARNRRGIL--VDELFVLPTLQE--
----SGDP--IW-R-RFF--SALDKVLHKVEP--YWPKNM---RAKAIHSCVHRLNGEDGL-----GAIYPAIANSVMMYALGYPENPARRAVEKLMVLD
GQGDKEVYCQPC-LSPIWDTALVAHAMLEVGGD-EAEKSAISALSWLKPQQILDVKGD-WAWRPDLRPGGWAFQYRNDYYPDVDDTAVVTMAMDRAAKLS
D---LRDDFEESKARAMEWTIGMQSDNGGWGAFDANNSYTYLNNIPFAD--HGALLDPPTVDVSARCVSMMAQAGISIT------DP-KMKAAVDYLLKE
QEEDGSWFGRWGVNYIYGTWSALCALNVAALPHDH-LAIQKAVAWLKTIQNEDGGWGENCDSYALSGYEP-MDSTASQTAWALLGLMAVGEANS--EAVT
KGINWLAQNQDEEGLWKEDYYSGGFPRVFYLRYHGYSKYFPLWALARYRNLKKA---
>sp|Q796C3|SQHC_BACSU Sporulenol synthase OS=Bacillus subtilis (strain 168) GN=sqhC PE=1 SV=1
--------------------------------------------------------------------------------------MGTLQEKVRRFQKK
TITELRDRQNADGSWTFCFEGPIMTNSFFILLLTSLDE---GENKELISSLAAGIHAKQQPDGTFINYPDERGNLTATVQGYVGMLASGFHRTEP---HM
KKAEQFIISHGGLRHVHFMTKWMLAANGLYPWPAL-YLPLSLMALPPTLPIHFYQFSSYARIHFAPMAVTLNQRFVLINRNISS--LHHLDP---TK---
-----NPF--TWLRSDAFEERDLTSILLHWKRVFHAPFAF---QQLGLQTAKTRIEKDGTL-----YSYASATIYMVYSLSLGVSRYPIRRAITGIKSLV
TKCNGIPYLENS-TSTVWDTALISYALQKNGVT-ETDGSVTKAADFLLERQH-TKIAD-WSVNPNSVPGGWGFSNINTNNPDCDDTTAVLKAIPRNHSP-
----------AAWERGVSWLLSMQNNDGGFSAFEKNVNHPLIRLLPLESA-EDAAVDPSTADLTGRVLHFLGEKVGFTE------KHQHIQRAVKWLFEH
QEQNGSWYGRWGVCYIYGTWAALTGMHACGVDRKH-PGIQKALRWLKSIQNDDGSWGESCKSAEIYVPLH--RGTIVQTAWALDALLTYENSEH--PSVV
KGMQYLTDSSSHSA-DSLAYPAGGLPKQFYIRYHSYPYVFSLLAVGKYLDSIEK---
>sp|B3Y522|DCD_DRYCA Dammaradiene synthase OS=Dryopteris crassirhizoma GN=DCD PE=1 SV=1
-----------------------------------------------------------MLPYNQDFYN----EDEAL-KDDHCEGNVSNPPTLDEAIKR
SQDFLLSQQYPEGYWWAELEGNPTITSHTVILYKILGI---E-DEYPMDKMEKYLRRMQCIHGGWELFYGDGGQLSVTIESYVALRLLNVPPTDP---AL
KKALKFIIDKGGVXKSRMFTKICLALLGCFDWRGIPSLPPWVMLLPGWFLSSIYETACWARGCVVPLIVVFDKKPVFKVSPEVS--FDELYAEHACKT--
LP---FCG--DWTS-HFF--IAVDRVFKMMER--LGVVPF---QQWGIREAEKRQEDTGDF-----LGVYPPMFYSVVCMTLGYEVTPVRRALLSFKKFS
IR-ADECSVQSS-LSPVWDTALVVRSLVESGLP-PDHPALQRAGEWLLQKQI-TKHGD-WSFNQSGVAGGWAFQFFNRWYPDLDDSAVVVMALDCLKLPN
E-----DVKNGAITRCLKWISSMQCKGGGWAAFDKDNHQHWINSTPFSD--LKAMVDPSTTDISARVLEMVGRLKLHGTSFDAHLPPESIARGLVYLRRE
QENEGCWFGRWGVNYIYGTCGALVALSLVAPMTHE-EEIARGARWLVQVQPQDGGWGETCFSYNDLKGQG-DVSTASQTAWALQGLLAAGDAEV--ESIG
HGVQYLLSTQRKDGSWHESQFTGGFPIHFYLRYHFYAQHFTLSSLARYRTRLQA---
>tr|A0A0E0G0Z5|A0A0E0G0Z5_ORYNI Uncharacterized protein OS=Oryza nivara PE=4 SV=1
MWRLKVAESGTPLLRSTNGFLGRAVWEFDPDHGTPEDRADVERVRREFTDHRLHHRESADLLMRMQQNKHQRRRYRIP-PNKLGEKEEVTEEIAMASLRR
ALDEFSSLQADDGHWPGDFSGVMFIMPGL------------------------------NEDGGWGSLILSSSTMFGTCSNYITLRLLGEETSNE---QL
AKGRIWIILHGGPTLVPQWGKIWFSILGVYEWAGNSPIFPELWLTPQFLPFHPGKFWCLTRMVYLPMAYLYGKKFVGPTTPTILALREEIYSAHYLTIDW
AQARSACAKEDLVCPRTRLQNAVWSWLYKWVEPVMSSWAMSKLRGRALDRLMAHPLRRREH----------AALNMVCCWAEDPNSDAFKQHLARVPDFL
WLSEDGMKAQVYDGCQSWETAFIIQAFCATDLVNEYASTVQRAHEFLKNSQVVRNHPGDQSYHRHRSKGSWTLSSADNGWAVSDTTAEALKAVLLLTKIS
INVVGDPIERERLHDAVDCLLSFV------------------------------------------------------------ISRMHVLSASSFGAIQ
RTVPWLPLGTWGVCFTYGAFFSVKGLIAAGRTYENSSSIRKACDFIMSKQLNTGGWGESHVSNETYVNIKGDHAHAVNTAWAMLTLIYAGQMERDPAPLH
CAAKELINMQLETGEFPQQQPPPFAGRVAQTSPSSYTSFFQLTSSMTLYGFAEM---
>tr|A0A0E0JVD3|A0A0E0JVD3_ORYPU Uncharacterized protein OS=Oryza punctata PE=4 SV=1
MWRLKVAEGGGALLRSTNGFLGRAVWEFDPGHGTPEDHA-VERLRREFTD-------------------HRLRRRETP-PVELGENEQVSEEIAMASLRR
ALDEFSSLQADDGHWPGDFSGIMFIMPGLKNVC-----------------------YST------------------------IHKLLGEEPNNE---EL
AKGRTWIISHGGATLIPQWGKIWLSILGVYEWTGNNPIFPELWLAPQFLPFHPGKFWCLTRMVYLPMAYLYGKKFEDL----------------------
------------VCPQTRVQNAVWSWLYKWVEPVMSSWAMSKLRGRALDRLMEHIHYEDEN----------KALNMVCCWAENPNSDAFKRHLARVPDFL
WLSEDGMKAQVYDGCQSWETAFIIQAFCATDLVNEYASTVERAHKFMKNSQVVRNHPGDQSYHRHRSKGSWTLSSADNGWAVSDTTAEALKAVLLLANNS
SNLVGDPIERERLLDAVDCLLSFVNKDGTLSTYE-----------------------------------------CKRTATWIEIS-----SASSFGAVQ
RTTPWLPLGTWGVCFTYGAFFSVKGLIAAGRTYENSSSIRKACDFILSKQLSSGGWGESHVSNETYVHIKGDRAHAVNTAWAMLTLIYAGQMERDPAPLH
RAAKELINMQLETGEFPQQEHVGCFNCSLFFNYPNYRNLFPIWALGEYCRHL-----
>tr|A0A0E0JVD0|A0A0E0JVD0_ORYPU Uncharacterized protein OS=Oryza punctata PE=4 SV=1
LMRLQVEAAGERWRSSTNSHAGRQVWEFDAAAADDDDAAEIEAARREFSRRRHQIKHSSDLLMRLQV--SNPSKLEIP-GIKLGEDEDVTEEAVLTSLKR
AILRYSTLQAHDGHWPGDYAGPMFLLPGL------------------------------NEDGGWGLHIEGTSTMFCTVLTYVTLRLLGDESDDG---AM
VIARNWILDRGGATFTTSWGKFWLSVLGVFDWSGNNPLLPELWMLPYFLPFHPGRMWSHCRMVYLPMSYIYGRKFVGPITPAILNLRRELYNMPYDDIDW
DKARNQCAKEDLYYRHPLGQDILWATHYKFVEPVLSHWPGSKLREKALKNAMQHIHYEDEQ----------KVLNMLSCWIEDPNSEAFRLHIPRVHDYL
WIAEDGMKMQGYSGSQLWDTAFTVQAILATNLVEEFGTTIKLAHDYIKNSQVLYDWPGDLSYYRHISKGAWTFSTADHGWAVSDCTAEGLKASLLLSKFS
PEIVGEPLGANRLYDAINCLLSWMNNNGGFATYE-----------------------------------------LTRSYAWLELIDNCIQKADRFIQSI
QRSDGSWYGSWAVCFTYGTWFGVKGLIAAGRTYENCPAIRKACDFLLSKELRYGGWGESHLSCKDYTNLEGDRPHVANTSWAMLALIDAKQGERDPAPLH
RAARILINLQLEDGEFPQQEIIGAFGKNCAISYSQYRNIFPIWALGEYRC-------
>tr|A0A067JM13|A0A067JM13_JATCU Uncharacterized protein OS=Jatropha curcas GN=JCGZ_22566 PE=4 SV=1
MWRLKIAEGGEPYLYSTNNYVGRQIWEFDPDAGTPEERAAAEQVRQNFYNNRYQVKPSSDLLWRMQFLKEKKFKQTIP-AVKIKEGEQITYDKATAALRR
AVQFFSALQASDGHWPAENAGPLFFLPPLVMCVYITGHLDTVFPPEHRKEILRYIYYHQNQDGGWGLHIEGHSTMFCTVLSYICMRILGVGPDQDN--AC
ARARTWIHDHGGVTYIPSWGKTWLSILGVYDWSGSNPMPPEFWLLPSFLPMYPAKMWCYCRMVYMPMSYLYGKRFVGPITPLILELRRELHTQPYHQINW
KKTRHLCAQEDLYYPHPLLQDIMWDTLYLFTEPLLTRWPFSSIRNKALQVTMKHIHYEDEE----------KVLCMLACWVEDPDGDYFKKHLARIPDYL
WVAEDGMKMQSF-GSQQWDTGFAIQALIATNFTQEIGDVLKRGHNFIKESQVKENPSGDFKSHRHISKGSWTFSDQDHGWQVSDCTAEGLKCCLLFSMMP
PEIV----------------------------------------------------------------------------------ENFIVNAVRYLENV
QTREGGWYGNWGVCFTYGTWFALGGLAASGKTYNNSAVVRKGVDFLLGIQKEDGGWGESYLSCPQ-----------------------------------
---------------------------------------------------------
>tr|A0A0E0N9M3|A0A0E0N9M3_ORYRU Uncharacterized protein OS=Oryza rufipogon PE=4 SV=1
MYRLKVAEGGGALLRSTNGFLGRAVWELDPDHGTPEDRADVERVRREFTDDRLRRRESADLLMRMQFAKQRRRDSIPP-AVKLGEKEQVTEEIAMASLRR
ALDEFSSLQADDGHWPGDFSGVMFIMPGL------------------------------NEDGGWGTFLS-SSTMFGTCSNYITLRLLGEVLTNE---QL
ARGRIWIISHGGATLVPQWGKIWLSILGVYEWAGNNPIFPELWLAPQFLPFHPGKFWCLTRMVYLPMAYLYGKKFVGPTTPTILALREEIYPVHYLTIDW
AQARSACAKEDLVCPRTRLQNAVWSWLYKWVEPVMSSWAMNKLRGRALDALMEHIHYEDENTQYLCICSVNKALNMVCCWAEDPNSDAFKRHLARVPDFL
WLSEDGMKAQVYDGCQSWETALIIQAFCATDLVNEYASTVQRAHEFMKNSQVVRNHPGDQSYHRHRSKGSWTLSSADNGWAVSDTTAEALKAVLLLTKIS
SSMVGDPIERERLYDAVDCLLSFVNKDGTISTYECKRTSTWIEISRMYLLS-------------------------------------------------
------------------------A-SSFGAVQRTMPWLPKACDFILSKQLNTGGWGESHVSNETYVNIKGDRAHVVNTAWAMLTLIYAGQMERDPTPLH
CAAKELINMQLETGEFPQQEHVGCFNCSLLFNYPNYRNIFPIWALGEYCWHLR----
>tr|A0A0E0CFB9|A0A0E0CFB9_9ORYZ Uncharacterized protein OS=Oryza meridionalis PE=4 SV=1
KVA-EEGTGGEGWLSSTNAHIGRQVWEFDAAAADDDDAEEVEAARREFSRRRHQIKHSADLVMRLQVVYSNPSKLEIP-GIKLGEDEDVTEEAVLTSLKR
AIRRYSTLQAHDGHWPGDYAGPMFLLPGL------------------------------NEDGGWGLHIEGTSTMFCTVLTYVTLRLLGDESDGG---AM
VIARNWILDHGGATFTTSWGKFWLSVLGVFDWSGNNPLLPELWMLPYFLPFHPGRIWSHCRMVYLPMSYIYGKKFVGPITPIVLTLRKELYNIPYHDINW
DKARNQCAKEDLYYRHPLGQDILWATLYKFVEPVLSHWPGSKLREKALKNAMQHIHYEDENTRYICSGAVQKVLNMLSCWIENPNSEAFRFHIPRVHDYL
WVAEDGMKMQGYNGSQLWDTAFTVQAILATNLIEDFGPTIKLAHDYIKNSQLLHDCPGDLSYYRHISKGAWTFSTADHGWAVSDSTAEGLKASLLLSKIS
PEIVGEPLKVNRLYDAVNCLLSWMNNNGGFATYELTRSYAWLEIFNPSETFGDIMIDYPYVECTSGVVQGLTAFRKHYPGHRRE-------EIDNCIQKA
DSFIQSIQRSDGSWYGSWAVCFTSGTIAAGRTYENCPAIRKACDFLLSKELPCGGWGESHLSCKDYTNLEGERPHAVNTSWAMLALIDAGQGERDPAPLH
RAARILINLQLEDGEFPQQEIIGAFSKNCAISYSQYRNIFPIWALGEYRCRVL----
>tr|D7KVW8|D7KVW8_ARALL Putative uncharacterized protein OS=Arabidopsis lyrata subsp. lyrata GN=ARALYDRAFT_316793 PE=4 SV=1
MWRLKIGSGDDPYLFTTNNFVGRQTWEFDPDAGSPEERYAVVEARQSFYDNRFHVKASSDLLWRMQFLKEKKFEQVIA-PVKVEGSEKVTFETATNALRR
GVHFFSALQASDGHWPAENAGPLFFLPPL------------------------------VFCGGWGLHIEGHSTMFCTALNYICMRILGESPVGN---AC
RRAREWILSHGGVTYIPSWGKTWLSILGVFDWSGSNPMPPEFWILPSFFPVHPAKMWCYCRMVYLPMSYLYGKRFVGPITSLILQLRKELYLQPYEEINW
MKVRHLCAKEDTYYPRPLVQELIWDSLYIFAEPFLGRWPFNKLRQKALQVTMKHIHYEDENSRYITIGCVEKVLCMLACWVEDPNGNYFKKHLARISDYL
WVAEDGMKMQSF-GSQLWDTGFALQALLASNLSSEISDVLRRGHEFIKDSQVGENPSGDFRSYRHISKGAWTFSDRDHGWQVSDCTADGLKVIQPFKPNT
LTLLPAVQDPERLYDSVNILLCFQSKNGGVSAWEPAGAPEWLELLNPTELFSDIVIEHEYSECTSSAIQALSLFKQLFPHHRTT-------EITTFINKA
VHYLESMQTPDGSWYGNWGICFTYGTTAAGKTYNDCEAIRKGVQFLLGAQKDNGGWGESYLSCSKYIAKEGEMSNVVQTAWALMGLIHSGQAERDPVPLH
RGAKLIINSQLESGDFPQQQATGVFLKNCTLHYASYRNIHPLWALAEYRARVS----
>tr|A0A061G7X8|A0A061G7X8_THECC Terpenoid cyclases family protein OS=Theobroma cacao GN=TCM_027369 PE=4 SV=1
MWRLKIGEGGDPYLYSTNNYLGRQTWEFDPNAGTPKERAEVEEVRQNYYNNRKHVQPSSDLLWQIQFLREKNFKQTIP-QPKVEDGEEITFEATTAAVRR
SVHFFSALQSKDGHWPAENAGPMFYFPPLVMSLYITGHLHTIFFAEHRKEILRYIYCHQNEDGGWGLYIGGHSTMFCTALNYICMRLLGEGPDGGLNNAC
ERSRKWILDRGGVTTIPSWGKTWLSILGVYEWSGCHPIPPEFWLLPSYFPIHPAKMFCYCRLTYMPMSYLYGRKFVGPITPLIVQLREELHIEPYNEINW
SKKRHLCAKEDLHYPHTMLQIFLWDSLYIFTEPLLNCWPFNKLREKALKVTMNHIHYEDESSQYITIGCVEKPLCMLACWVEDPNGVYFKKHLARIADYV
WVGEDGIKMQSF-GSQVWDASLTLQALLASQLFDEIGPILMKGHNFLKNSQVRDNPPSDFKRFRHISKGSWTFSDRDHGWQVSDCTAESLKCCLYFAMMP
PEMVGEKMELKQFYDSVNVILSLQSENGGLSAWEPTGGGFWWEWLNPVEFLEDLVKEYEYVECTSSSIQALVLFQKLYPEHKKREIANFISKAAQFLEEI
QYPDGSWYGNWGICFIYGTWFGLQGLKAAGKTYNNCLAIRKGVDFLLKTQREDGGWGESYLSCPKYIPSEGNRTNLVQTALALMGLIIGGQAERDPTPLH
RAAKLLINSQLPNGDFPQQELAGVFMRNCMLHYALYRNVFPLWALAEYCKHFW----
>tr|M7ZWG9|M7ZWG9_TRIUA Terpene cyclase/mutase family member OS=Triticum urartu GN=TRIUR3_02578 PE=3 SV=1
---------------------------------------------------------------------------NLP-PIKLEQGYHIEEDDVLISLRR
AINRCSTLQAHDGHWPGDYAGTLFLLPSL-----------------------------------------------------------------------
-------------------------VLGVYDWSGNNPLPPELWMMPYFLPIHPGRMWCNCRLVYLPMSYLYGKRFVGATTSIVLDLRKELYNVPYNEINW
DKARNGCAKEDLYYPHSPLQNIVWATLKKIGEPVLMHWPGSNLRKKALDIVMKHIKYEDETTQYICIAPLNKMLNMICCWVEDPKSEAFKLHIERVYDFL
WVAEDGMKMKSYNGSQLWDTALTVQAIFATGLTKEFGHTIKVAHDYIKHSQIRADCPGDQSKYRHLSKGGWTHSTADQGWPVSDCTAEAFKVLLLLTKVP
-ELVDEPIETSRLDDAVNILLSLMNDDGSFGAYELTRSYEWLELLNPSESFGGIMIEYPYVECTSSVIQGLVLFREMYPEHSLEEIDSCIQKAADYIESI
QWSDGSWYGCWAICFTYGTWFGVRGLVAAGRTYVNSLAIRKACEFLLSKELPSGGWGESYLSSQDYTNLEGNRAHAVNTSWAMLALIDAGQGQRDPACLH
RAAKILMNFQSEDGEFPQQDIIGATNHNLMLTYAQFRNIFPIWALGEYYRRVLL---
>tr|Q964Q1|Q964Q1_TRYCR Terpene cyclase/mutase family member (Fragment) OS=Trypanosoma cruzi GN=ERG7 PE=3 SV=1
-----------------------------------------------------------------------------------------RRASPEDAMRD
GVEFLLRLQDYSGHWPNDYSGPLFLTPGFIFTKFIVGDIRKMFPEAERVEMIRYLRNYMNKDGGFGQHTEGHSTMLGTALNYVALRFMGVPADDA---DA
TRARAWIRSHGGAVSVPTWGKVWLCIVGLYSWDGINPIPPELSLLPAWFPLSQGRLWCHSRVISVPFSYLYGIRWAPEPHPLLEALRQELYTEPYDQIQW
DQHQSNICNLDCYTPLSSTYKLVAVLLKLYE-----KWHIKSLRRHALEVAWSHVAYDDEDTKFICLGPVNKALDMLLTWREGEKSGRYQNHVSRVADFI
YMGPEGMRVCGYNGSQLWDTSFAVQAVCACNMELLYPQQMSLAHHYVDVAQVQKDPKS-AAHYRHRTKGAWNFSTASQSWQVSDCTAEGLRVVLLLRHNP
-------FSVSRIRDAVDEILSLRNAKGGWASYEPTRAPLYVELFNSSDVFRDVMTDYGYAECSSSCIHTLALFREHYPGYRRAEINAAIREGLKFVLSL
QRPDGSFYGSWGVCFTYAAWIVASALCISREIPDNHPSCVRLIDFLLSHQNADGGWGEDVTASVRWVDNP-SGSQVVNTAWAVMAIMSAGEAARSLVAVE
RGIRLIMSRQLVTGDWAQERISGVFNGNNPIHYPGYKNTMPVWALGMYNT-------
>tr|R9TL35|R9TL35_TRYRA Lanosterol synthase OS=Trypanosoma rangeli PE=4 SV=1
-----------------------------------------------------------------------------------------RRASSEDAMRD
GVEFLLQLQDYSGHWPNDYSGPLFLTPGLIFVRFLIGDLHKMFPEAARLELIRYLRNYINKDGGFGQHTEGHSTMLGTVLNYVALRLMGVPAEDA---DA
ARARAWIRDHGGAVSIPTWGKVWLCIVGLYNWDGINPIPPELSLLPNWVPLSQGRLWCHSRVVSVPFSYLYGVRWTPKPHPLLRSLRQELYTEPYHQISW
VQHQSNICKLDCYTPLSSTYKFTATMFKLYE-----RLHSKALRRYALEVAWSHIAYDDEDTNFICLGPVNKLLDMLITWREGESSGRYQNHLTRVDDYL
YMGPEGMRMNGYNGSQLWDTSFAVQAICACSMELLYPQEMALAHHYVDIAQVRRDPEA-ADAYRHRTKGAWNFSTAAQSWQVSDCTAEGLRVILLLRHRP
-------FSVSRMRDAVDEILSLRNKRAGWASYEPMRAPAYAELFNAADVFKDVMTDYGYAECSSSCIHTLALFRQHYPGYRRTDVNTAIREGIQFVLSL
QRPDGSFYGSWGVCFTYAAWLVACALCISREIADNHPSCVRLIDFLLSHQNADGGWGEDVTACMRWVDSP-SGSQVVNTAWAVMAIMSAGEAARVPVAVE
RGIRLIMSRQLITGDWAQERISGVFNGNNPIHYPGYKNTMPVWALGAYNA-------
>tr|C9ZTG7|C9ZTG7_TRYB9 Chromosome 7, complete sequence OS=Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) GN=TbgDal_VII6010 PE=4 SV=1
-----------------------------------------------------------------------------------------PRGSVEEAMRA
GAEFLLRLQHYSGHWPNDYSGPLFLTPGVIFVRYIVGNIRNMFPEAERLELIRYIRNYMNEDGGFGQHTEGHSTMLGTVLNYVALRLMGVSDDDS---DA
ARARQWIRGEGGAVSIPTWGKVWLCVLGLYEWDGVNPIPPELSLLPNWIPFSPSRLWCHSRVVSIAFSYLYGLRWRQPDNLLLQCLRYEIYLEPYGNIKW
AKHRSNICAKDCYTPLSSVYKVFAAVMSLYE-----KRPIKFLRRRALEVAWTHIAYDDESTHFICLGPVNKAFDMLITWREGETSGRYLNHLNRLDDYF
FMGPEGLRMSGYNGSQLWDTSFAVQALCACNMELLYPEEMALAHHYVDVAQVQENPVA-ATQYRHRTKGAWNFSTRPQAWQVSDCTAEGLRVLLLLRHKP
-------FPHQRIYDAVDQILSLRNRGGGWASYEPTCAPHYVELLNCSDVFKDVMTDYVYTECTSSCVHTLSLFREHFPDYRREDVDRAIRDGVKCMLAN
QRTDGSYYGSWAVCFTYAAWLCASALRISGEIYSRHPTCVRLVNFLLSHQNTDGGWGEDVSACARWVDNP-SGSQVVNTAWAVMAIMASGEASSTEKAVS
AGIHFIVSRQLSTGDWAQERISGVFNGNNPIHYPGYKNTMPVWALGVYRR-------
>tr|A4H4N0|A4H4N0_LEIBR Complete genome, chromosome 6 OS=Leishmania braziliensis GN=LBRM_06_0650 PE=4 SV=2
-----------------------------------------------------------------------------------------LRTTSEAAMDD
GIRFLLKLQDFSGHWPNGYSGCLFLCAGFVITKYIVGETRRMFPEAMRQELIRYIRNHQNLDGGWGQHTEGHSTMMGTVLNYVSLRLLGVPASDP---QA
TCGRSWILAHGGATTTPMWGRVWLSILGVYSWDGVNPISPEMLLMPDWVPFSLGKMWCHSRVIAIPFSYFYGLRWSAPAFPTTLALRKELYTEPYATIPW
RSFRGVVCELDVYSPTSPLFRVAMGLLDLYE-----RHPIPFLRRYALEVSWRHMAYDDENTHFICLGPVNKWLNMLATWREGEHSARFQEHCDRVSDYF
YMGETGLSMSGYNGSQLWDTSFAVQAICACRREMMFPAEVELAHHYIDVAQVQEDPMA-APYYRHRTKGAWNFSTRSQGWQVSDCTAEGLRALLLLPQYA
-------FPMRRIFDGVDEVLSLRNSGGGWASYEPSRAPAYCELLDCSELFKDVMIDYSYVECSSSCIHTLSLFRERYPHYRRRDVDRAISEGIAYVLGQ
QQPDGGFYGSWAVCYTYAAWLVADALQASKELPESHPHCMRLIDFLLSHQAADGGWSEDISASARWVDSP-DGSQVVNTAWAVMAIISAGKAASTERAVD
RGVQLIMSRQLASGDWRQERISGVFNGNNPIHYPGYKNSMPVWALGKYNM-------
>tr|W6KUT5|W6KUT5_9TRYP Genomic scaffold, scaffold_3 OS=Phytomonas sp. isolate EM1 GN=GSEM1_T00004643001 PE=4 SV=1
-----------------------------------------------------------------------------------------PRETSEQAMQD
GLSFLMRLQDFSGHWPNGYGGCLFLTPGVLFTKFIVGNLDRMFPEATRLELIRYIRNYQNDDGGWGQHTEGHSTMLGTVLNYIALRMMGVAAADL---SM
ASARRWIHAEGGAVYTPLWGRIWLCILGLFSYDGVNPLSPELVLLPRWISFSIGRSWCHSRVIAMSFLYFYGLRWSASRHPLLEALKEELFVQPFHTICW
RRYRYEVCPKDLYTPVSRTYKVFCKVLELYE-----RRPISFLRRYALEKNWQHIAYDDENTHFICLGPVNKSLNMLVTWREGENSVRYQLHRQRVDDYF
FMSPYGMHMSGYNGSQLWDTSFAVQATCACKSEMLFANEMALAHHYIDIAQVRDDPIQ-KDYYRHRTKGAWNFSTKDQSWQVSDCTAEGLRAVLLLRHMP
-------FPTARIFDAVDEILSLRNSSGGWASYEPSRAPHYCELLNCSEMFKDVMVEYSYAECSSSSIHTLSLFREQFPYYRRSSIDTAISEGIAYIFST
QNPDGSFYGSWGVCFTYAAWLVSDALRISKEFSNDHPRCRLLADFLMSHQNNDGGWGEDINACVRWVDNP-DGSQVVNTAWAVMAIMNSGDPNHSSSAVE
RGIQLIMSRQLATGDWAQERLSGVFNGNNAIHYPGYKNTMTVWALGMYNT-------
>tr|A4HSV6|A4HSV6_LEIIN Putative lanosterol synthase OS=Leishmania infantum GN=LINJ_06_0670 PE=4 SV=1
-----------------------------------------------------------------------------------------PRTTSEAAMDD
GIRFLVKLQDFSGHWPNNYSGCMFLVAGFVITKYIVGETDRLFPEATRQELIRYIRNHQNPDGGWGQHTEGHSTMMGTVLNYVSVRLLGVPASDP---QA
TCARNWILAHGGATKTPMWGRVWLSILGVYSWDGVNPIPPEMILMPDWIPFSLGKMWCHSRVIAMPFSYFYGLRWSAPAFPTTLALRKELYTEPYDAIPW
RSFRGVACELDVYTPTSPLLRVATGLFDLYE-----RHPIPFLRRYALEENWRHIAYDDESTSFICLGPVNKWLNMLATWREGEHSARFQKHCHRVQDYF
YLENTGLSMSGYNGSQLWDTSFAVQAICACRREMTFPAEMELAHHYIDVAQVQANPMA-AADYRHRTKGAWNFSTRAQGWQVSDCTAEGLRVLLLLPQYE
-------FPVRRIFDGVDEVLSLRNSGGGWASYEPTRGPAYCELLDCAELFKDVMIDYSYVECSSSCIHTLSLFREHYPHYRRRDVDRAISEGIAYVLGQ
QQPDGGFYGSWGICYTYAAWLVADALQASKELPDVHPHCVKLVDFLLSHQGADGGWSEDVSASARWVDSP-DGSQVVNTAWAVMAIICAGKAAHTESAVD
HGVQLIMSRQLASGDWPQERISGVFNGNNPIHYPGYKNSMTVWALGKYNS-------
>tr|W6LGX3|W6LGX3_9TRYP Genomic scaffold, scaffold_11 OS=Phytomonas sp. isolate Hart1 GN=GSHART1_T00001640001 PE=4 SV=1
-----------------------------------------------------------------------------------------PRESSEKAMQD
GLAFLMRLQDFSGHWPNGYGGCMFLTPGFIFTKFIVGDLGRMFPEAKRLEFIRYLRNYQNDDGGWGQHIEGHSTMLGTVLNYISLRMMGVPAEDP---SA
ASARRWIHAEGGAVYTPLWGKMWLCILGLFSYDGVSPLLPELILLPRWIPFSIQRMWCHSRIITLPFLYLFGLRWSASPHPLLDALKMELFVQPFASICW
RRYRYEVCPKDLYTPVSSILKVASRVLDLYE-----RRPISFLRRYALEKYWQHIAYDDESTHFICLGPVNKCLNMLVTWREGENSARYQLHLQHINDYL
FMSPYGMYMSGYNGSQLWDTSFVVQATCACKSEMLFPNEMTLAHHYVDISQIRDDPIE-KDYYRHRTKGAWTFSTRKQFWQVSDCTSEGLRAILLLRHIP
-------FPTPRIFDAVDEILSLRNAGGGWASYEPKRAPRYCELLNCSEMFKDIMVECSYAECSSSCIHTLSLFREQFPYYRRSSVNTAISEGIAYVFST
QNPDGSFYGSWAICYTSAAWLVSSALRVSKEFPNNHPHCRKLADFLMRHQNNDGGWGEDMNSCVRWVDSS-DGSQVVNTAWAVMAIMNSGEPYHTNSAVD
RGIQLIMSRQLDSGDWNQERINGMFNGNNPIHYPGYKNSMTVWALGMYNT-------
>tr|S9VJ31|S9VJ31_9TRYP Lanosterol synthase OS=Angomonas deanei GN=AGDE_01126 PE=4 SV=1
-----------------------------------------------------------------------------------------PSLNTETAMKD
GVEFLLKLQDFSGHWPNDYSGCMFLTPGLVFAEYIVGNTEAMFEAATRQELIRYLRNYQNKDGGWGQHTEGHSTMLGTALNYVAMRLLGVPATDA---QL
SQARSWIHAHGGAVYTPFWGKYWLTLLNLFDYEGIHPLPPEMLWLPRWFPFGYGRAWCHSRVIAIPFSYFYGMRWQAPLQPLLTEIRSEIYLQPYKGIQW
RHYRNELCNTDCYTPVSAFFKVIMKVLDVVE-----HTVLKCFRQSAIETCWRHMAYDDENTHFICLGPVNKSLNYLATWREGPRSTRVKLHKSRIPDYL
YPGPCGMKMNGYNGSQLWDTSFAVQAICACRQEMFHPEEMQLAHYYINVAQVQEDPID-MDRFRHRTKGAWNFSTSPQGWQVSDCTAEGLRVVLLLKQFH
-------FTESRIVDAVEEILSLRNVGGGWASYEATRAPAYCELFNCAELFKDVMVEYSYAECSSSCIHSLSLFRKLYPQHRRREVDRAIREGIACVLRK
QRPDGSFYGSWAVCFTYSAWIVSDALRASGELEDNHPHCQKMIHFLRQHQNADGGWGEDINACVRWVDNP-DGSQVVNTAWAVMAIMCAGDSNKLCKAVE
NGIQFICYRQLTDGDWAQERISGVFNGNNPIHYPGYKNSMTVWALGMYNE-------
>tr|L8YE42|L8YE42_TUPCH Lanosterol synthase OS=Tupaia chinensis GN=TREES_T100008087 PE=4 SV=1
-----------------------------------------------------------------------------------------KAHTAHEGALN
GTTFYVGLQAEDGHWPGDYGGPLFLLPGLLITCHVANI---PLPAGCREEIVRYLRSVQLPDGGWGLHIEDKSTVFGTALNYVSLRILGIGPDDP---DL
VRARNILHKKGGAVGIPSWGKFWLAVLNVYSWEGLNTLFPEMWLFPDWAPAHPSTLWCHCRQVYLPMSYCYATRLSASEDPLVLSLRQELYVDDFDSINW
PAQRNNVASDDLYTPHSWLLRVMYVLLNLYER-HH----STILRQRAIQKLYEHIAADDRFTKSISIGPISKTINMLVRWVDGTASPAFQEHVSRIPDYL
WLGLDGMKMQGTNGSQIWDTSFAIQALLEAGVHPEFSSCLQKAHEFLRLSQVPDNPPDYQKYYRQMSKGGFSFSTLDCGWIVADCTAEALKSVLLLQERC
P-FVTEHIPREQLCNAVAVLLNMRNPDGGFATYENKRGGLLLELLAEPPFPGDIMIDYTYVECTSAVMQALKLFHRQFPDHRAMEIRDTLEKGLEFCRQK
QRPDGSWEGSWGVCFTYGTWFGLEAFACMGQSYWNCAEVSQACDFLLSRQMADGGWGEDFESCEQYVQSA--QSQVHNTCWALMGLMAVRHPDI--AAQE
KGIRYLLEKQLPNGDWPQDNISGVFNKSCAISYTNYRNIFPIWALGRFSRLYPE---
>tr|A0A091D7H5|A0A091D7H5_FUKDA 80 kDa MCM3-associated protein OS=Fukomys damarensis GN=H920_10443 PE=4 SV=1
-----------------------------------------------------------------------------------------KAHTACEGALN
GITFYVGLQAEDGHWTGDYGGPLFLLPGLLITCHVARI---PLPAGYREEMVRYLRSVQLPDGGWGLHIEDKSTVFGTALNYVALRILGIGPDDP---DL
VRARNILHKKGGAVAIPSWGKFWLAIMNVYSWEGLNTLIPEMWLFPAWMPAHPSTFWCHCRQVYLPMSYCYAARLSASEDPLVLSLRQELYVEDYASIDW
PAQRNNVSPDDLYTPHSWLLRTVYVLLNLYER-FH----STRLRRWAIQMLYEHITADDRFTKSISVGPISKTINMLVRWVDGPASLAFQEHVSRIPDYL
WLGLDGMKMQGTNGSQIWDTSFTIQALLEAGAHSEFLSCLQKAHAFLRLSQVPDNPPNYQKYYRQLNKGGFSFSTLDCGWIVADCTAEALKAVLLLQEKC
P-SITEHIPREQLCNAVAVLLNMRNPDGGFATYETTRGGRLLELLNPSEVFGDIMIDYTYVECTSAVMQALKCFHKNYPDHRAAEIKETLEQGLAFCRQK
QWDDGSWEGSWGVCFTYGTWFGLEAFACMGHTYQDCTEVSRACNFLLSRQMVDGGWGEDFESCEQYMQSA--QSQVHNTCWALMGLMAVRHPDV--EAQE
RGVRCLLEKQLPNGDWPQENISGVFNKSCAISYTNYRNIFPIWTLGRFANLYPE---
>tr|M7AX19|M7AX19_CHEMY Lanosterol synthase OS=Chelonia mydas GN=UY3_13592 PE=4 SV=1
----------------------------------------------------------------------------------------------------
--KFYSGLQAEDGHWAGDYGGPLFLLPGFLITCHVAKI---PLPEGYRREMVRYLRSVQLPDGGWGLHVEDKSTVFGTALNYASLRILGVGPDDP---DL
VRARINLHSKGGAVGIPSWGKFWLAVLNVYSWEGMNTLLPELWLLPTWMPAHPSTLWCHCRQVYLPMSYCYATRLTAEEDELVQSLRQELYVQDYSSIDW
PAQRNNVAACDLYTPHSWLLTLANAILNVYEAHHS-----ARLRQRAIAELYDHIKADDRFTKAISIGPISKTINMLVRWVEGESSPAFQEHVSRIPDYL
WLGLDGLKMQGTNGSQLWDTAFAVQAFLEAGAQPAFASCLRQAHEFLKITQIPDNPPDYQKYYRQMSKGGFPFSTRDCGWIVADCTAEGLKSVMLLQETC
P-FIAEHVPTGRLFDAVNVLLSMRNPDGGFATYETKRGGRLLELLNPSEVFGDIMIDYCYVECTSAVVQALKHFHEAFPEHRAQEVRETLRKGLEYCCRV
QRADGSWEGSWGVCFTYGTWFGLEALACLQHTYENCKEVSQACQFLVSKQMEDGGWGEDFESCEQYVQSP--TSQIHNTCWALLGLMAVRYPDV--GVLE
KGIKVLIDKQLPNGDWPQENISGVFNKSCAISYTSYRNVFPIWALGRFARLHPG---
>tr|A0A024SC02|A0A024SC02_HYPJE Oxidosqualene:lanosterol cyclase OS=Trichoderma reesei RUT C-30 GN=M419DRAFT_136748 PE=4 SV=1
RWRVKDDD-------------SRHTWHYLADDK------AAAEWPQSYAEKWY------------LNL-----PLDLP--------ALPKAETPLQAAEN
GLTFFEKLQLPSGHWGCEYGGPMFLLGGIVITWYVTKT---PIPDAYATEIKNYITARAHPDGGWGLHIEGESTVFGTAMNYIVLRLIGVDAEDP---VM
VKARATLHKMGGAVNAPHWAKFWLAVLGVVDWDIVNPVPPEIWLLPDWVPIAPWRWWIHIRQVFLPMGYIYSKRWSCEETDITRELKQELFVQPHAEINW
ASHRNRISPIDNYHPKSWLLNSVNWVLVNVYNPYLR---FNFIKERGEKWVSELVDMEDANTEYACLAPVNAPMNTLVCYRDGPDAFTTQRHIERLDEYL
WVKDEGMLCNGTNGVQCWDTAFAILAAVESGLHERWKPMLVKALEYLDRQQIRENCKD-QEKYRQPRKGGWPFSNRDQGYGVSDCISEALKAVILLQKTE
GPQL---LEDRRIFDAVDTLLLYQNDNGGVSSYEARRGGEYLEMLNAAEVFGRIMIEYDYPECTTACVTALSLFHKHWPDYRTKDVELFIKRATNWIKTN
QRPDGSWYGSWGICFTYAGMFALQSMAAIGETYANSQIARAGCDFLISKQREDGGWSESYRACETYVEHE-SGSQVVQTAWALIGLMAVDYPDV--AKIK
KGIRLITSRQQANGEWLQEAIEGVFNKSCMISYPNYKFTFTIKALGMFAKRYPD---
>tr|E9E2H1|E9E2H1_METAQ Oxidosqualene:lanosterol cyclase OS=Metarhizium acridum (strain CQMa 102) GN=MAC_04069 PE=4 SV=1
RWRMKDDD-------------SRHTWHYLATKK------AAEEWPQSYAEKYY------------LGL-----PLDLP--------ALPKPETPLDSAKN
ALEFFQKLQLPSGHWGCEYGGPMFLLAGIVVAWYVTKT---PIPSAYATAIRDYLAARAHPDGGWGLHIEGESTVFGITLNYTVLRLVGVDPEDP---LM
VKARGTLHKLGGAVNSPHWGKFWLATLGVVSWDIVNPVPPEIWLLPDWVPIAPWRWWIHIRMVFLPMGYIYSKRWSCEETDVIRGLKEELFTQPHTEINW
AAHRNSIAPGDNYHPKSWLLNTMNWLIVNVWNPYLR---TNFIKERAEQWVSQQVDMEDANTGYADLAPVNAPMNTIVCYRDGPDAFSTKRHIERLDEYL
WVNDEGMLCNGTNGVQCWDTAFLIQGVFEAGLQERWRPMLTRALEYLERQQIRENCVD-QEKYRQPRKGGWPFSNRDQGYGVSDCISEALKAIILLQKVG
GPAV---LGDQRIFDAVDTLLLYQNDNGALSSYEARRAGEYMEMFNAAEVFGRIMIEYDYPECTTACVTALSLFSKHWPDYRSKEIKIFINRATNWIKTN
QRVDGSWYGSWGICFTYATMFALESMASIGETYSNSKISRRGCDFLISKQREDGGWSESYKACETYHEHP-MGSLVVQTAFALIGLLEADYPHI--EPLK
KGIKLIMERQQENGEWLQEAIEGVFNKSCMISYPNYKFTFTLKALGLFAKSTYS---
>tr|N4UFE7|N4UFE7_FUSC1 Lanosterol synthase OS=Fusarium oxysporum f. sp. cubense (strain race 1) GN=FOC1_g10014553 PE=4 SV=1
RWRLKDDD-------------SRHTWHYLENDD------DAKEWPQSYAEKWY------------LNL-----PMDLP--------DLPTPDNPLAAAEN
GLDFFEKLQLPSGHWGCEYGGPMFLLPGIVMT-----------------------------------------CVFGTLMNYVALRLVGVDPEDP---VL
VKARGTLHKMGGALYAPHWAKFWMAILGVMSWDIVNPVPPEFWLLPDWVPFAPWRWWIHIRMVFLPMGWLYSKRWSCEETDVIRSLKKEVFLEDYAKINW
SSHRNSIGVVDNYHPKSWLLNAANWVLANIWMPYLR---PNFLKEKAEAWASKQVDMEDANTGYACLAPVNASMNTVLCYRDGPDDYGVKRHIERLEEYL
WVKDEGMLANGTNGVQCWDTAFLIQAVFEAGLHEKYRPMLMKSLHYLERQQIREDCVD-QEVYRQPRKGGWPFSNRDQGYGVSDCISEALKAIILLQKVG
GPEV---LEDRRLFDAVDTLLLYQNDNGGMSSYEKRRGGEWLEMLNAAEVFGRIMIEYDYPECTTACVTALSMFNKHWPDYRTDEVRTLIRTAAEWIKSN
QGPDGSWYGSWGICFTYAGMFALESMKHIGQTYATGENSRRGCDFFISKQRADGGWSESYKACETYVEHP-SGSLVVQTAWALIGLMEAEYPHV--EPLR
RGIQFIMDRQKPNGEWLQEAIEGVFNKSCMISYPNYKFTFTIKALGMFAKRFPE---
>tr|L7HS12|L7HS12_MAGOY Lanosterol synthase OS=Magnaporthe oryzae (strain Y34) GN=OOU_Y34scaffold00936g23 PE=4 SV=1
RWRMLDDE-------------GRHTWHYLEDDE------AVKEWPQSYADKWY------------LGL-----PMDLP--------TLPEPKKPLDAVVN
GLDFFEKLQLPPGNWGCEYGGPMFLMPGLVISWYVTKT---PIPWPVATEIKNYLFARANADGGWGLHIEGESTVFGTALNYTTLRIVGVDADHP---AM
VKARTTLHKLGGTTQAPHWAKFWLAVMGVVPWDLVNPVPPELWLLPDWVPFAPWRWWIHMRMVFLPMSYIYSKRWQGETTDLVKELRQELFAEPYEKINW
AANRDSIAPRDNYHPKTWLLTAANWAIVNVWNPFLR---PDFLKKRAEDWVSKLVDMEDENTDYADLAPVNGAMNMVVCYKDGPDSYAVKRHRERSQEFL
WVNKEGLMVNGTNGVQCWDTAFAIQAVMDAGLTRRWKPMLLKALEFLDDQQIRENSKW-QDEYRHPCKGAWGFSNKDQGYAVSDCISEALKSVIILQKTP
GPQL---ISDRRIFDAIDTLLTYQTENGGCASYEPPRGSEKLEMLNAAEVFGRIMVEYLYPECTTACVTALSLFHKHWPDYRASEVKTFIHKAVNWIKTD
QRPDGSWYGSWGICFTYAGMFALESLASIGETYRDSESSRKGCDFLVSKQREDGGWSESYRACEEYNEHP-MGSLVVQTAWAIIGLMKADYPHI--EPIR
KGVKLIMQRQQPNDCGCKS------------SDST----------------------
>tr|Q5ATX0|Q5ATX0_EMENI Uncharacterized protein OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) GN=AN8260.2 PE=4 SV
RWRLLDDD-------------GRQTWHYLETDE------ENHEWPQSIADKYF------------LGL-----PTGLP--------QLPKAKTPMQCAEN
GLEFFSKLQLPPGNWACEYGGPMFLLPGLIITYYVTNT---PIPPEYATEIIRYLFARQHPDGGWGLHIEAHSSVFGTSMNYVVLRLLGVGEDDP---RM
IKARGLLHSFGGAVYGPHWSKFWLSILGVMDWDCVNPVPPELWLLPDWVPFAPWRWWIHMRQVFLPMSYLWSKKFTYPLTPLTKQLRHELYTQPYDSIDF
ASHRNSIHKADNYYPKTWLLNSLNSLLVNVWNPFFR---TSAIVKRAEDWTWELIRMEDENTDYAGLGPVNNPMNMIACLHDGPDSYSVRRHRERLHDYM
WMKDEGMLMNGTNGVQVWDTAFITQAIVVAGFAPKWRPMLTKALGFLDAHQLRENVPN-QEKYRQHRKGAWPFSNKTQGYTVSDCTAEGLRSTIQLQEMH
NPKM---ISEERLKDSVDCLLLMQNPSGGFTEYETTRGSPKIEWLNAAEVFGGIMIGYDYPECTTASVTALSLFSKFYPNYRAEEIKAAKDKAVKYIKRV
QRADGSWYGSWGICFTYAAMFALESLASIGETYETSNYARRGCEFLISKQKEDGGWGESYLSSEKYVQHE-K-SQVCQTAWACLALMEAGYPHK--EPLQ
KAMKLIMSRQQPNGEWLQEAIEGVFNQSCMISYPNYKFYWPIRALGLYSRKFGN---
>tr|D1C5C0|D1C5C0_SPHTD Squalene-hopene cyclase OS=Sphaerobacter thermophilus (strain DSM 20745 / S 6022) GN=Sthe_2007 PE=4 SV=1
---------------------------------------------------------------------------------------------MDPALSR
AVDWLLEHQDPAGWWCGEFETNVTITAEHILLLRFLGLDPSP----LRDAVTRYLLGQQREDGSWALYYEGPADLSTSIEAYAALKVLGLDPTSE---PM
RRALQVIHDLGGVAQARVFTRIWLAMFGQYPWDGVPSMPPELIWLPPSAPFNLYDFACWARATITPLLIILARRPVRPL-G-C---DGELVLPGS-EH--
-----------LLTRGPF--WWGDKVL-KR----YDHLVRHPGRDRACQRIVEWIIAREADGSWGGIQSAWVLIALHLELPLDH--PVMRAGLAGFDRVA
LEDERGWRLQAS-TSPVWDTAWAVLALRRAGLPR-EHPRLALAVDWLLQEQIP--GGGDWQVTGTIPGGGWAFEFDNDHYPDIDDTAVVVLALLEAGH--
-----EDRVRNAVERAARWILAMRSTDGGWGAFDRDNAREV---IHPIADFGTL-IDPPSEDVTAHVLEMLARLS-------FPSTDPVVARGLEFLQQT
QRPDGAWFGRWGVNYIYGTWCAVSALTAFADTDAARAMVPRAVAWLLDRQNADGGWGETCGSYEDLAGVG--RSTPSQTAWAVLALQAAGLGQ--HPACR
RGLDFLRERQ-VGGTWEEREHTGGFPGDFFINYHLYRHVFPTMALAGAATGMDSP--
>tr|A0LVK9|A0LVK9_ACIC1 Squalene-hopene cyclase OS=Acidothermus cellulolyticus (strain ATCC 43068 / 11B) GN=Acel_1697 PE=4 SV=1
---------------------------------------------------------------------------------------------AKAALDR
AVDYLLSLQDEKGFWKGELETNVTIEAEDLLLREFLGIRTP-D--I-TAETARWIRAKQRSDGTWATFYDGPPDLSTSVEAYVALKLAGDDPAAP---HM
EKAAAYIRGAGGVERTRVFTRLWLALFGLWPWDDLPTLPPEMIFLPSWFPLNIYDWGCWARQTVVPLTIVSALRPVRPI-PL-----DEIRTGAPPP-R-
----------D----GFF--QRLDDLL-RG----YRRV-ARLFRRLAMRRAAEWIIAREADGSWGGIQPPWVLIALHLLYPLDH--PVLRRGLDGLNGFT
IREEAVRRLEAC-QSPVWDTALAVTALRDAGL--PDHPRVQAAARWLVGEEVR--VAGDWAVRPGLPPGGWAFEFANDNYPDTDDTAEVVLALRRVRLED
---ADQQALEAAVRRATTWVIGMQSTDGGWGAFDADNTREL---VLPFCDFGAV-IDPPSADVTAHIVEMLAALG-------MR-DHPATVAGVRWLLAH
QEPDGSWFGRWGANHIYGTGAVVPALIAAGVSPD-TPPIRRAIRWLEEHQN-DGGWGEDLRSYTDWVGRG--VSTASQTAWALLALLAAGE--AS-PAVD
RGVRWLVTTQQPDGGWDEPHYTGGFPGDFYINYHLYRLVFPISALGRYVNR------
>tr|W2EZV1|W2EZV1_9ACTO Squalene-hopene cyclase OS=Microbispora sp. ATCC PTA-5024 GN=MPTA5024_05080 PE=4 SV=1
---------------------------------------------------------------------------------------------AEAALSA
ARDHLLGLQSPEGWWKGELQTNVTMDAEDLLLREFLGVRTA-E--D-TAGAARWIRSQQRADGTWATFHGGPGDLSTTVEAYVALRLAGDPPEAP---HM
RAAAAFAREAGGVEATRVFTRIWLALFGQWPWDDLPVLPPEMILLPPWFPLNVYDWACWARQTIVPLTIVSAHRPVRPL-PF-----AELRTGRRPHG--
---------------AAF--DALDRAL-HR----YGRR-VPWLRRAALRRAAEWVVAREADGSWGGIQPPWVLIALHLERGLDD--PVVRRGLEGLERFT
IRD-NGRRLEAC-QSPVWDTALAVGALLDAGV--PRHPAVDRAATWLLGEEIT--VTGDWAVRPALPPGGWAFEFDNDGYPDIDDTAEVILALRRTGRA-
----D---ARPAIARGLRWMAGMASRDGGFAAFDADNTRAL---CTPFCDFGAV-IDPPSADVTAHVVEALAAEG-------HA-RSPVVRRAVLWLLRA
QEPDGSWFGRWGANHVYGTGAVLPALLAAGVRPG-AACVRRGAAWLRAHQN-DGGWGEDLRSYRDWIGQG--ASTASQTAWALIGLLAADG--S--PAVE
RGVRWLTGHQRPDGTWDEPHFTGGFPGDFYINYHLYRLVFPVGALGRYLRAGEDA--
>tr|C7Q017|C7Q017_CATAD Squalene-hopene cyclase OS=Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897) GN=Caci_6664 PE
---------------------------------------------------------------------------------------------AAATLQA
AADHLLGLQDDAGWWKGELETNVTMDAEDLLLRQFLGIRTE-E--V-TREAGDWIRSQQRADGTWANFFDGPADLSTTIEAYTALRMAGDAKDAE---HM
RAARTYILDSGGIEASRVFTRIWLALFGEWQWSDLPVMPPELIYLPKWFPLNVYDWACWARQTVVPLTIVNALRPVRPL-GF-----KELRTGRRAA---
---------------GLF--STLDRAL-HV----YERK-LRSVRDAALRRSADWIIAREADGSWGGIQPPWVLMALNLLYGVDH--PVMRKGIEGLDRFT
IRD-RGRRLEAC-QSPVWDTVLAMTALRDAEL--PNHPALVKAADWVLGEEIT--NPGDWSVRPRVAPGGWAFEFDNDGYPDVDDTAEVVLALNRVAHP-
----D---APAAIRRGVDWLEGMACKDGGYGAFDADNTRTL---ALPFCDFGAV-IDPPTADVTAHTLEAYAALG-------LA-NSRASQRALEWLVKA
QERDGSWFGRWGANHVYGTGAVVPAMVAVGVDPE-DEMIRRAVRWLEEHQN-DGGWGEDLRSYRDWIGRG--VSTASQTAWALLALLAAGE--RG-TAVE
QGVRFLIRTQRADGTWDEDHYTGGFPGDFYLNYHLYRLVFPISALGRYVRAVGAA--
>tr|L7F854|L7F854_9ACTO Squalene-hopene cyclase OS=Streptomyces turgidiscabies Car8 GN=shc PE=4 SV=1
---------------------------------------------------------------------------------------------AERAMRR
ATDSLLARQDSQGWWKGDLETNVSMDAEDLLLRQFLGIRDE-Q--T-TQAAALFIRGEQRDDGTWATFHGGPADLSATVEAYVALRLAGDEPEAP---HM
ARASAWIRDRGGIAAARVFTRIWLALFGWWKWDDLPELPPELIYFPKWMPLNIYDFGCWARQTIVPLTIVSAKRPVRPA-PF-----EELHTDPDLNPGK
----------S----GAF--QRLDKVL-HG----YRKV-VRRLRKAAMNAAARWIIERENDGCWGGIQPPAVVIALHLLYDLEH--PVMRAGLDSLDRFT
VWRE-ARMIEAC-QSPVWDTCLAVIALADAGL--PDHPQLVKAADWMLGEQVV--RPGDWSVRPELPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHH-
----DPERVEKAIGRGVRWNLGMQSKNGAWGAFDVDNTSTL---PNPFCDFGEV-IDPPSADVTAHVVEMLAVEG-------MS-HDPRTRRGIEWLLAE
QEPNGAWFGRWGVNYVYGTGSVVPALTAAGLTAA-HPAIRRAVGWLEKVQN-DGGWGEDLRSYQDWSGRG--ASTPSQTAWALLALLAAGE--DS-KAVE
RGVEWLAANQLPDGSWDEPYFTGGFPWDFSINYHLYRLVFPLTALGRYVHGEPFA--
>tr|A0A0D7CGX0|A0A0D7CGX0_9ACTO Squalene-hopene cyclase OS=Streptomyces natalensis ATCC 27448 GN=SNA_26275 PE=4 SV=1
---------------------------------------------------------------------------------------------ARRATAR
ATDHLLALQDPAGWWKGDLETNVTMDAEDLLLRQFLGVTDP-K--L-TEAAARFIRGEQSADGTWATFHGGPGELSATIEAYVALRLAGDAPNAP---HM
ARAAAWIRDRGGIASARVFTRIWLALFGWWRWEDLPELPPELIYVPKWLPLNIYDFGCWARQTIVALTIVSAKRPVRPA-PF-----DELHADPRRNPPR
----------P----GLF--QRLDRAL-HV----YHKV-PRRLRRNAMRTAAQWIIERENDGCWGGIQPPAVLIALHLLYDLDH--PVLRHGLASLDRFA
VWRE-ARMIEAC-QSPVWDTCLATIALADAGL--PDHPQLVKAADWMLDEQVL--RPGDWSVRPQLPPGGWSFEFENDNYPDIDDTAEVVLALRRVEHP-
----DPQRVDAAIRRAVRWNLGMQSRNGAWGAFDADNTSRF---PNPFCDFGEV-IDPPSADVTAHVVEMLADVG-------RS-HDPRTRRGLEWLLAE
QEPSGAWFGRWGTNYVYGTGSVLPALAAAGIPAS-HPAVRRAVGWLERVQN-DGGWGEDQRSYQDWAGRG--ASTPSQTAWGLMALLAAGE--ES-QAVR
RGVRHLVDTQRADGSWDEPHFTGGFPWDFSINYHLYRQVFPLTALGRYVHGGPAD--
>tr|F4D0Z8|F4D0Z8_PSEUX Squalene-hopene cyclase OS=Pseudonocardia dioxanivorans (strain ATCC 55486 / DSM 44775 / JCM 13855 / CB1190) GN=Psed_3680 PE=4 
---------------------------------------------------------------------------------------------PRAALDA
AVAFLRAGRHPDGWWQGELETNVTMDAEDLLLREFLGIRTE-T--E-TAEAARWIRSRQRADGTWATFQDGPPDLSTTVEAWVALRLAGDDPAAE---HM
RRAQHHVLAHGGLERTRVFTRIWLALFGLWSWDELPDMPPELIFLPKWFPLNVYDWACWARQTVVPLTVVATLRPSRPL-PF-----DELRTGAVPP-P-
----------A----GAF--QRLDRVL-HA----YSRR-LRGLRRLAMRRAAEWVLAREADGSWGGIQPPWVLLALHLLYPLDH--PAVAAGLRGLDRFL
VREDVVRRLEAC-QSPVWDTCLAVTALLDAGV--PDDPDVLAAADWLLAEEVRD-VRGDWAVRPDIPTGGWAFEFDNDGYPDTDDSAEVVLALRRVAHP-
----DPARLRAAVDRGVAWTVGMQSSDGGWGAFDADNTREL---ITPFCDFGAV-IDPPSADVTAHVVEMMAAEG-------LA-GTDACRRGVDWLLAA
QEPDGSWFGRWGANHVYGTGGVVPALVAAGVSPT-APSIRRAVAWLERHQN-DGGWGEDLRSYDDWIGKG--ASTPSQTAWALLALLAAGE--DS-AATA
RGVRYLVDTQLPDGSWEETLYTGGFPGAFYIRYHLYRMVFPVSALGRYVHGEGTR--
>tr|A0A0B2ABM2|A0A0B2ABM2_9MICC Squalene-hopene cyclase OS=Sinomonas sp. MUSC 117 GN=LK10_18410 PE=4 SV=1
---------------------------------------------------------------------------------------------AQACLDA
AVQHLLGLQHDGGWWQGELETNVTMDAEDLLMRQFLGVRTA-E--Q-TAQSARWIRSQQRADGSWANFYGGPPDPSTTAEAYVALRLAGDAPEEP---HM
RRARAVVLEHGGLEQTRVFTRIWLALFGVWSWDEVPALPPELIFLPPQFPLNLYDFACWARQTIAPLTVLAALRPRAEL-GF-----DELRADPARRAPE
---------PA----RAF--GLLDTVL-HR----YETTRGRGMRATALRRTVEWIVEREADGSWGGIQPPWVLMALHAFYALDH--PVLAKGLAGWERFT
ITEEMVRRIEAC-QSPVWDTALALTALADAGL--PGHPSLERAADWICAEEIR--VRGDWSLRPDVPPGGWAFEFDNDGYPDIDDAAEVIMGLDCTQPT-
-----P-ERGSAASRGRDWILGMQSRDGGWAAFDADNTREL---AYPFCDFGAV-IDPPSADVTAHVVEMLARRG-------EE--GPALERGVRWLLDH
QEADGSWFGRWGANYVYGTGAVVPALTLAGLPRD-RGPVRRAVQWLCAQQN-DGGWGEDLRSYEDWAGRG--ESTASQTAWALLALHAADE--DG-DAAR
RGVDWLVGHQRPDGGWDEPQFTGGFPGDFYINYHLYRLVFPVSALGRCLRRSAR---
>tr|I0V7I9|I0V7I9_9PSEU Squalene-hopene cyclase OS=Saccharomonospora xinjiangensis XJ-54 GN=SacxiDRAFT_3901 PE=4 SV=1
---------------------------------------------------------------------------------------------VRHSIAS
ATRHLLSLQHEEGWWKGELETNVTMEAEDLLLRQFLGIADP-V--V-TEETARWIRSRQREDGTWATFHDGPADLSTSVEAYTALRLAGDPLDAG---HL
RKAREYILDSGGIEATRVFTRIWLALFGQWPWRKLPVLPPELMLLPDWFPLNIYDWACWARQTVVPLTIVGAARPTRQL-GF-----RELRTGVERESD-
----------P----GLF--HRLDAVL-HR----WERL-IKPMRDTALQRAEQWILDREADGGWGGIQPPWVILALHLRYPVDH--PVIRKALDGLEGFT
VRERWVRRLEAC-QSPVWDTALAMTALLDSGT--HDDPALIAAADWMLREEIR--IGGDWQVRPQLTPSGWAFEFANDHYPDTDDTAEVVLGLRRVRHP-
----EPSRVEAAVQRATEWLLGMQSSDGGWGAFDADNTRAL---CEPFCDFGAV-IDPPSADVTAHVVEMLAARG-------MA-DCEAARRGVRWLLEA
QEADGSWFGRWGANHVYGTGAVVPALVACGVPRD-HESVRAAVHWLTAHQN-DGGWGEDLRSYVDWVGRG--RSTASQTAWALLALLAAGE--G--AVVR
RGVEWLVTTQRPEGGWDEPEFTGGFPGDFYINYHLYRLVFPLTALGRYLGSGQDA--
>tr|M9SGX4|M9SGX4_9ACTO Squalene-hopene cyclase OS=Streptomyces albus J1074 GN=XNR_0267 PE=4 SV=1
---------------------------------------------------------------------------------------------AERARAR
AVDHLLGLQSPEGWWKGDLDTNVTMDAEDLLLRQFLGIRDE-A--T-TRSAALFIRGEQREDGTWATFHGGPPDLSTTVEAYVALRLAGDSPDAP---HM
TRAAHWVRSQGGIAEARVFTRIWLALFGWWPWDRLPELPPELIFLPPWAPLNIYDFGCWARQTIVPLTVVSAKRPVRPA-PF-----DELHTDPADAPRA
----------R----GAF--QRLDRAL-HA----YRKV-PRALRRAAMATAGRWIVERENDGCWGGIQPPAVMIALHLLYDLGH--PVMRAGLESLDRFT
LTRE-SRMVEAC-QSPVWDTCLATIALADAGV--PDHPQLVRAADWMLDEQIE--RPGDWSVRPHLAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHP-
----DTARMERAISLGVRWNLGMQSKNGAWGAFDVDNTSSL---PNPFCDFGEV-VDPPSADVTAHVVEMLAAEG-------LA-ADPRTRRAVDWLLAE
QEPSGAWFGRWGVNYLYGTGSAVPALVDAGLPTT-HPAIRRAVAWLESVQN-DGGWGEDLRSYRERMARG--ASTASQTGWALMALLAAGE--ES-RAAR
RGVTFLAETQHEDGSWEEPYYTGGFPWDFSINYHLYRQVFPLTALGRYTRGAAPE--
>tr|T2RRV0|T2RRV0_SACER Squalene-hopene cyclase OS=Saccharopolyspora erythraea D GN=N599_26990 PE=4 SV=1
---------------------------------------------------------------------------------------------PAEVLAA
AREHLLSLQHERGWWKGELETNVTMDVEDLLLRRFLGILTT-A--E-TEQAARWIRSRQRADGTWAQFHGGPGDLSTTVEAYVGLKLAGDDVDSE---HM
AAARAWILERGGIEETRVFTRIWLALFGEWSWDDLPAMPPELVLLPPWVPLNLADWGCWARQTIVPLTVVCTLRPRRDL-GV-----AELRSGRR---RR
---------KV----GAF--QVLDGAL-HG----YQRH-LRGLREHAMRRAAEWIVAREADGSWGGIQPPWVLLALHLLYPLDH--PVLRQGLAGLERFL
IREETVRRLEAC-QSPVWDTVLSMQALRDAGL--ADHPALRRAADFVLAEEIR--VKGDWSVRPDLAPGGWAFEFDNDGYPDIDDTAEVVLALNRVDHE-
----RPGAVNAAIDRGVRWMSGMQSADGGWGAFDADNTREL---VNPFCDFGAV-IDPPSADVTAHVVEALCVLG-------RG-DGEAVRRGVRWLLDH
QELDGSWFGRWGANHVYGTGAAVPALVRAGLRRD-HLALRRAVRWLEVHQN-DGGWGEDLRSYDDWVGRG--RSTASQTAWALLALLAVDL--DT-DAVR
RGVGFLAETQRPDGTWDEPQFTGGFPGDFYINYHLYRLVFPVTALGRYEQARREQ--
>tr|I1D3H6|I1D3H6_9PSEU Squalene-hopene cyclase OS=Saccharomonospora glauca K62 GN=SacglDRAFT_02608 PE=4 SV=1
---------------------------------------------------------------------------------------------VRRCVDS
ARRYLLSLQHAEGWWKGELETNVTMEAEDLLLRQFIGASDP-R--V-TEETARWIRSRQREDGTWATFHDGPPDLSTTVEAYAALRLAGDPLDAT---HL
RRAREYILDSGGIEATRVFTRIWLALFGQWSWSKLPVLPPELVLLPDWFPLNIYDWACWARQTVVPLTIVASARPARQL-GF-----RELRTGVERGSD-
----------P----GVF--RGLDAVL-HR----LERL-LKPLRAAALDRAERWILDREADGGWGGIQPPWVILALHLRYPLDH--PVIRKALDGLEGFT
VRERWVRRLEAC-QSPVWDTALAMTALLDSGT--PDHPALVAAADWLLREEIR--VAGDWRVRPELAPSGWAFEFANDHYPDTDDTAEVVLGLRRVRHP-
----EPDRIEAAVERATEWLVGMQSADGGWGAFDADNTRTL---CEPFCDFGAV-IDPPSADVTAHVVEMLAARG-------MA-DCEAARRGVRWLLDA
QEADGSWFGRWGANHVYGTGAVVPALVACGVSRD-HEAVRAAVHWLTAHQN-DGGWGEDLRSYVDWVGKG--RSTASQTAWALLALLAAGE--G--PVVR
RGVEWLVSTQRPDGGWDEPHYTGGFPGDFYINYHLYRLVFPLTALGRYLGRGHDA--
>tr|G2G9G7|G2G9G7_9ACTO Squalene-hopene cyclase OS=Streptomyces zinciresistens K42 GN=SZN_10738 PE=4 SV=1
---------------------------------------------------------------------------------------------AVRAVGR
ATDLLLAQQDAQGWWKGDLETNVTMDAEDLLLRQFIGIRDE-A--T-TRAAGLFIRGEQREDGTWATFYGGPGELSATIEAYVALRLAGDPPDAP---HM
ARAAAWIRDRGGIAEARVFTRIWLALFGWWKWEDLPELPPELIYFPTWVPLNIYDFGCWARQTIVPLTIVSAQRPVRPA-PF-----DELHTDPAHNPTK
----------P----GAF--QRMDKVL-HR----LRKV-PRGLRRAAMNSAARWIIERENDGCWGGIQPPAVVIALHLLYDLQH--PVMRAGLASLDRFA
VWRE-ARMIEAC-QSPVWDTCLATIALVDAGV--PDHPQLVRAADWMLGEEIV--RRGDWAVRPGLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHP-
----DRERMERAIGRGVRWSLGMQSRDGGWGAFDVDNTSPF---PNPFCDFGEV-IDPPSADVTAHVVEMLAVEG-------LT-RDPRTRRGVRWLLAE
QEPDGSWFGRWGVNYVYGTGSVVPALVAAGLPGT-HPAIRRAVGWLESVQN-DGGWGEDLRSYRHWSGKG--ASTASQTAWALMALLAAGE--DS-TAVE
RGVAWLAATQRADGSWDEPYFTGGFPSDFSINYHLYRQVFPLTALGRYVYGEPFA--
>tr|H6RL60|H6RL60_BLASD Shc protein OS=Blastococcus saxobsidens (strain DD2) GN=shc PE=4 SV=1
---------------------------------------------------------------------------------------------AATALAA
GRDWLLARQEPGGWWQGELETNVTMDAEDLLLREFLGIRTD-A--E-TAETAAWIRSRQRDDGSWATYTGGPGDLSTTVEAYVALRLAGDDPGSA---HL
RRAAGFVVAHGGLEASRVFTRFWLAMFGEEPWARLPVLPPELVLLPRRMPLNVYDFASWARQTIVPLAVVGALRPRRPL-PF-----AELRAGAAPARP-
----------V----RAF--LGLDRLL-HR----YERR-LKGLRRLALARAERWILEREADGSWGGIQPPWVLIALHLLHPLDS--PAVQAGLAGLDRFT
VRS-GLRRLEAC-QSPVWDTALTVLALTDAGV--PDDPALRRAAGWLVGEEIR--IRGDWSVRPDLVPSGWAFEFDNDWYPDVDDTAEVALALCRTAAAE
---ADGGPARAAVDRGVAWLVGMQSRDGGWGAFDADNTSRL---CRPFLDFGEV-TDPPSADVTAHVVETLAHTG-------AA-GSPAARRGVDWLLDA
QEPDGSWFGRWGVNHVYGTGAVVPALVAAGVDPG-ARPIRRAVSWLEEHQG-DGGWGEDPRSYTDWRGRG--RPTASQTAWALLALLAAGE--G--PAVE
RGIGWLTATQRPDGSWDEPEFTGGFPGDFFINYHLYRQVFPLMALGRYLGEGRTR--
>tr|D6A2Y0|D6A2Y0_9ACTO Squalene-hopene cyclase OS=Streptomyces ghanaensis ATCC 14672 GN=SSFG_00909 PE=4 SV=1
---------------------------------------------------------------------------------------------AARAMRR
ATDFLLSRQSDQGWWKGDLETNVTMDAEDLLLRQFLGIRDE-G--T-TRAAALFIRGEQREDGTWATFHGGPGDLSATIEAYVALRLAGDPPDAP---HL
ARASAWIREQGGIAASRVFTRIWLALFGWWKWEDLPELPPELIWFPAWVPLNIYDFGCWARQTIVPLTIVSAERPVRPA-PF-----DELHTDPARNPPR
----------A----GAF--QRLDKAL-HV----LRGA-PRRLRRAAMNTAARWIIERENDGCWGGIQPPAVIIALHLLYDLNH--PVMRAGLESLDRFA
VWRE-ARMIEAC-QSPVWDTCLATIALADAGL--PDHPQLVKAADWMLGEQIV--RPGDWSVRPHLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVAHH-
----DPERVDNAIGRGVRWNLGMQSRNGAWGAFDVDNTSPF---PNPFCDFGEV-IDPPSADVTAHVVEMLAAEG-------LA-HDPRTRRGVQWLLAE
QEPNGSWFGRWGVNYLYGTGSVVPALTAAGISGS-HPAIRRAVAWLESVQN-DGGWGEDLRSYRDWSGRG--ASTASQTAWALMALLAAGE--ES-RAVE
RGVEWLAATQHEDGSWDEPYFTGGFPWDFSINYHLYRQVFPLTALGRYVNGEPLA--
>tr|A0A089XK65|A0A089XK65_STRGA Putative squalene-hopene cyclase OS=Streptomyces glaucescens GN=SGLAU_28290 PE=4 SV=1
---------------------------------------------------------------------------------------------AVRATLR
ATDFLLSRQDPEGWWKGDLETNVTMDAEDLLLRQFLGIRDE-R--T-TRAAALFIRGEQREDGTWATFHGGPGELSTTIEAYVALRLAGDAPDAP---HM
AKAAAWIRARGGIAAARVFTRIWLALFGWWKWEDLPELPPELIWLPSWMPLNIYDFGCWARQTIVPLSIVSAKRPVRPA-PF-----DELHTDPARVPPR
----------P----GAF--QRLDKGL-HV----LRRA-PKRLRRAAMNTAARWIVERENDGCWGGIQPPAVIIALHLLYDLRH--PVMREGLASLDRFA
VWRE-ARMIEAC-QSPVWDTCLATIALADAGL--PDHPRLVKAVDWMLGEEVV--RRGDWAVRPELPPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHP-
----EPARVERAIGRGVRWTLGMQSRNGAWGAFDVDNTSPF---PNPFCDFGEV-IDPPSADVTAHVVEMLAVEG-------LA-HDPRTRRGIEWLLAE
QEPDGSWFGRWGVNYIYGTGSVVPALVAAGLPAA-HPAIRRAVTWLESVQN-DGGWGEDLRSYRHWRGRG--ASTASQTAWALMALLAAGE--DS-RAVE
RGVAWLVATQREDGSWDEPYFTGGFPWDFSINYHLYRQVFPLTALGRYLHGEPFH--
>tr|W7STV7|W7STV7_9PSEU Squalene-hopene cyclase (Fragment) OS=Kutzneria sp. 744 GN=KUTG_07981 PE=4 SV=1
---------------------------------------------------------------------------------------------VDLARRR
AIDHLVSLQDGDGWWKGELQTNVTMDAEDLLMRQFLGIREP-A--G-TAETAGWIRSQQRADGTWATFYGGPGELSTTVEAYTALKLAGDPADAD---HM
VRARQFVLDNGGIEKSRVFTRIWLALFGEWSWDRLPVLPPEMILLPKWFPLNIYDWGCWARQTVVPLTIVGSMRPVRPL-GI-----AELKTGQPDPFE-
----------P----GFF--QRLDRVL-HL----HAKL-VKPLREFAIRKGLKWILAREADGGWGGIQPPWVILALHLRYPLDH--PVIKKALHGLDEFT
IKED-IRRLEAC-QSPVWDTALAVTALLDAGM--PDDPVLKSAGNWLLDEEVT--VRGDWAVRPSLPPGGWAFEFENDNYPDVDDTAEIVLALRRMLPA-
----D----EPAVRRAVEWTIGMQSRDGGWGAFDADNTRRL---AEPFCDFGAV-IDPPSADVTAHVLEMLAHEG-------LS-GLQPARRGLKWLLDN
QEADGSWFGRWGANHIYGTGAVVPALIAAGVPTV-HPSVRRAVKWLEQHQN-DGGWGEDLRSYRDWVGRG--DSTASQTAWALLALLSAGE--G--TATE
RGIRWLVATQRSDGTWDEPQFTGGFPGDFYINYHLYRLVFPLTALGRYLDG------
>tr|X0N1J0|X0N1J0_STRA9 Squalene-hopene cyclase OS=Streptomyces albulus PD-1 GN=P354_37315 PE=4 SV=1
---------------------------------------------------------------------------------------------AREATTR
ATDYLLSLQDPAGWWKGDLETNVTMDAEDLMLRQFLGIQDP-E--L-TEATARHVRGEQRPDGTWPTFYGGPGELSTTIEAYVALRLAGDAPDAP---HM
ATAAAWIREQGGIAASRVFTRIWLALFGWWKWDDLPELPPELIYFPKWFPLSIYAFGCWARQTIVPLTVVSAKRPVRPA-PF-----DELHADPRNNPPR
----------P----GLF--QRLDRAL-HL----YQKV-LRRPRAAAMRSAGRWIVERENDGCWGGIQPPAVVIALHLLYDLDH--PVLRAGLDSLERFA
VRRA-ARMIEAC-QSPVWDTCLATIALADAGV--PDHPQLVQAAEWMLGEQID--RPGDWSVRPQLPSGGWAFEFHNDNYPDIDDTAEVVLALLRVRHP-
----DPQRVAAAVDRAVRWNLGMQSKNGAWGAFDADNTSPF---PNPFCDFGEV-IDPPSADVTAHVVEMLAEVG-------RV-HDPRTRRGLAWLLAE
QEPSGAWFGRWGTNYVYGTGSVLPALTAAGIPTS-HPAVRRAVGWLERVQN-DGGWGEDQRSYQDWAGRG--ASTASQTAWALMALLAAGE--DG-EAVR
RGVRWLVENQLPDGSWDEPYFTGGFPWDFSINYHLYRQVFPVTALGRYVHGGPGT--
>tr|A0A086GKN2|A0A086GKN2_STRSC Squalene-hopene cyclase OS=Streptomyces scabiei GN=IQ62_39430 PE=4 SV=1
---------------------------------------------------------------------------------------------AAHAIRR
ATDFLLSRQDAEGWWKGDLETNVTMDAEDLLLRQFLGIRDE-K--T-TRAAALFIRGEQRPDGTWATFYGGPPELSATVEAYVALRLAGDDPAEP---HM
ARASAWIRERGGIAAARVFTRIWLALFGWWKWDDLPEMPPEIVYFPKWMPLNIYDFGCWARQTIVPLTVVSAKRPVRPA-PF-----DELHTDPGRNPPR
----------P----GAF--QRLDKVL-HG----YHKV-LKRLRRAAMNSAARWIVERENDGCWGGIQPPAVIIALHLLYDLQH--PVMRAGLESLDRFA
VWRQ-ARMIEAC-QSPVWDTCLAAIALADAGL--PDHPQLVKAADWMLGEEIV--RPGDWSVRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVKHH-
----DPERVEKAVRRGVRWTVGMQSGNGAWGAFDADNTSPF---PNPFCDFGEV-IDPPSADVTAHVVEMLAVEG-------LS-HDPRTRRGIEWLLAE
QEPNGAWFGRWGVNYVYGTGSVVPALVTAGLPAA-HPAIRRAVAWLETVQN-EGGWGEDLRSYRDWGGRG--ASTASQTAWALLALLAAGE--DA-KATE
RGIEWLARTQREDGSWDEPYFTGGFPWDFSINYHLYRQVFPLTALGRYVNGEPAV--
>tr|J2A3I3|J2A3I3_9ACTO Squalene-hopene cyclase OS=Streptomyces auratus AGR0001 GN=SU9_02125 PE=4 SV=1
---------------------------------------------------------------------------------------------ARRASAR
ATDHLLSLQDPAGWWKGDLETNVTMDAEDLLLRQFLGLQDP-E--L-TQAAARYIRGEQCPDGTWATFYGGPGELSTTIEAYVALRLAGDAPDAP---HM
AKASAWVREQGGIAAARVFTRIWLALFGWWKWDDLPQLPPELLYFPKWFPLNIYDFGCWARQTIVPLTIVSAKRPVRPA-PF-----DELHTDPRRNPPR
----------P----GVF--QRLDKAL-HL----YHKV-FRRLRRAAMRSAARWIIERENDGCWGGIQPPAVVIALHLLYDLDH--PVLRTGLASLDRFA
VRRA-ARMIEAC-QSPVWDTCLATIALADAGV--PDHPQLVQAAEWMLAEQID--RPGDWSVRPQLPSGGWAFEFENDNYPDIDDTAEVVLALRRVKHP-
----DPQRVEAAVRRAVRWNLGMQSKDGGWGAFDVDNTSPL---PNPFCDFGEV-IDLPSADVTAHVVEMLADVG-------RT-HDPRTRRGVAWLLAE
QDPCGAWFGRWGTNYVYGTGSVLPALAAVGIPRS-HPAVRRAVRWLEGVQN-DGGWGEDQRSYQDWAGRG--ASTASQTAWALMALLAAGE--DG-EAVR
RGVRWLAATQREDGSWDEPYFTGGFPWDFSINYHLYRQVFPLTALGRYLNGGPAV--
>tr|A0A076MTU2|A0A076MTU2_AMYME Squalene-hopene cyclase OS=Amycolatopsis methanolica 239 GN=shc1 PE=4 SV=1
---------------------------------------------------------------------------------------------AAETLDR
AVAHLKGLQRDGGWWKGEMQTNVTMDAEDLLMREFLGIRTA-R--E-TEEAARWIRSQQRADGTWATFHGGPGDLSTTLEAWVALRLAGDSPDEP---HM
RRAAEFVRAGGGVEASRVFSRIWLALFGLWSWDDLPNMPPELVLLPSWVPLNVYDWGCWARQTVVPLTVVGTLRPVRPL-PF-----DELRTGVKRGGL-
----------V----GAF--HYLDKAL-HL----YAKV-VKPVREFAMRQAAEWILAREADGGWGGIQPPWVLLALHLLYSLDH--PAMRAGLQGLEGFL
IREETVRRLEAC-QSPVWDTALAITALLDAGA--PDDPHVLKAVDWMLGEEIA--VRGDWAVRPGLDPGGWAFEFANDLYPDTDDTAEVVLGLRRVAHP-
----DRERLSGALDRAVAWVTGMQSRDGGWGAFDADNTQEL---TTPFCDFGAV-IDPPSADVTAHVVEMLAKEG-------KA-GSRECRRGVKWLLDH
QEPDGSWFGRWGANYVYGTGAVVPALVEAGVPAS-ATAIRRAVRWLAEHQN-DGGWGEDLRSYRDWAGRG--ESTASQTAWALLALLAAGE--DS-GVTV
RGVRWLAETQRPDGTWDEPQFTGGFPGDFYINYHLYRLVFPVTALGRYLERS-----
>tr|W5TSY1|W5TSY1_9NOCA Putative squalene-hopene cyclase OS=Nocardia nova SH22a GN=NONO_c55610 PE=4 SV=1
---------------------------------------------------------------------------------------------VRAATAA
AVGLLRSSQHEQGWWKGELATNVTMDAEDLLLREFLGIATP-E--V-TVPAARWIRSQQRADGTWATFHNGPGDLSTTAEAWVALRLAGDDPAAP---HM
RAAAEFVRAGGGIEQSRVFTRIWLALFGLWSWDDLPNLPPELILFPSWFPLNIYDWGCWARQTVVPLTVVATLRPCRPL-PF-----DELRTGARPPQA-
---------------GIF--QRVDTVL-HA----YAKL-MNIVREHAMRRAAEWILAREADGGWGGIQPPWVLLALHLLYSLDH--PAMRAGIEGLDGFV
VREQEVRRLEAC-QSPVWDTALATAALLDAGV--ADDPAVLRATDWLLGEQIT--TGGDWQVRPGLEPGGWAFEFANDVYPDTDDTAEIVIALHQVAHP-
----DQARLDAAVERAARWTIGMQSADGGWGAFDADNTSVL---PTPFCDFGAV-TDPPSADVTAHVVEMLAVLG-------RD-RERECRRGVRWLLDH
QEADGSWFGRWGANHIYGTGAAVPALVAAGTSPR-SKSIRAAVRWLENRQN-DGGWGEDLRSYRDWIGRG--ESTPSQTAWALLALLAAEE--DS-PATR
RGIAWLVRTQRPDGGWDEDHFTGGFPGDFYINYHLYRLVFPVWALGRYLRRVSDG--
>tr|A0A079VC69|A0A079VC69_STRRM Squalene-hopene cyclase OS=Streptomyces rimosus GN=DF17_01755 PE=4 SV=1
---------------------------------------------------------------------------------------------ARRATAR
ATDYLLSVQDAAGWWKGDLETNVTMDAEDLLLRQFLGIGDP-R--T-TEAAARHIRGEQRDDGTWATFYGGPGELSATIEAYVALRLAGDEPDAA---HM
ARAAAWIREHGGVAAARVFTRIWLALFGWWKWEDLPELPPELIWFPKWFPLNIYDFACWARQTIVALTIVCSVRPVRPA-PF-----DELHADPARNPPR
----------P----GVF--QRLDKGL-HL----YRKV-VRKLRRSALRAAASWIVERENDGCWGGIQPPAVIMALHLLYDLGH--PVLRQGLESLDRFA
VWREPVRMIEAC-QSPVWDTCLAAIALADAGL--PDHPQLVKAADWMLAEQIR--RPGDWSVRPRLPSGGWAFEFENDNYPDIDDTAEVVLALRRIQHP-
----DPERVDAAVQRAVRWNLGMQSKNGAWGAFDADNTSPF---PNPFCDFGEV-IDPPSADVTAHVVEMAADLG-------MT-HDARVRRGIRWLLAE
QEPDGSWFGRWGTNYIYGTGSVLPALAAAGIPAS-HPAVRRAVRWLERVQN-DGGWGEDQRSYHDWAGRG--ESTASQTAWALMALLAAGE--ES-AAVA
RGVRWLAGTQRDDGSWDEPYFTGGFPWDFSINYHLYRQVFPLTALGRYVNGGPAG--
>tr|S4AWE1|S4AWE1_9ACTO Putative Squalene--hopene cyclase OS=Streptomyces aurantiacus JA 4570 GN=STRAU_1138 PE=4 SV=1
---------------------------------------------------------------------------------------------ATRAMQR
STDFLLSRQDAQGWWKGDLETNVTMDAEDLLLRQFLGIQDE-S--T-TRAAALFIRGEQRDDGTWATFFGGPGELSTTIEAYVALRLAGDAPDEP---HM
ARASAWIREQGGIASARVFTRIWLALFGWWKWDDLPELPPELIYFPKWFPLNIYDFGCWARQTIVPLTIVSAKRPVRPA-PF-----DELHTDARVNPAK
----------P----GVF--QRLDKAL-HI----YHKV-PRGVRKAAMNSAARWIIERENDGCWGGIQPPAVIIALHLLYDLDH--PVLKTGLESLDRFA
VWRE-ARMIEAC-QSPVWDTCLATIALADAGV--PDHPGLVKAADWMLGEQIV--RPGDWSVRPGLTPGGWAFEFHNDNYPDIDDTAEVVLALRRVAHP-
----DKPRLENAIDRGVRWNLGMQSRNGAWAAFDVDNTSAF---PNPFCDFGEV-IDPPSADVTAHVVEMLAYEG-------KS-HDPRTRRGVEWLLAE
QEANGAWFGRWGVNYIYGTGSVLPALTAVGLPGS-HPAIRRAVAWLESVQN-DGGWGEDLRSYRQWIGHG--ASTASQTAWALIGLLAAGE--DS-KAVE
RGIAWLAEAQRDDGSWDEPYFTGGFPWDFSINYHLYRQVFPLTALGRYVNGEPLA--
>tr|B5GJ74|B5GJ74_STRSH Squalene-hopene cyclase OS=Streptomyces sp. (strain SPB74) GN=SSBG_04417 PE=4 SV=1
---------------------------------------------------------------------------------------------TARATRR
AVDFLLARQSDEGWWKGDLATNVTMDAEDLLLRQFLGIRDE-A--T-TRAAALFIRGEQQEDGTWNTFYGGPGDLSATIEGYVALRLAGDSPEAP---HM
RKASAFVRAQGGVARARVFTRIWLALFGWWKWEDLPEMPPELMFFPKWAPLNIYDFGCWARQTIVPLTVVCAQRPVRPA-PF-----EELHTDPADDPAQ
----------P----NVF--HKLDKLL-HG----YRRI-PRRVREAAMRAAATWIVERENDGCWGGIQPPAVIMALNLLYDLDH--PVLRAGLASLDRFA
VWRE-ARMIEAC-QSPVWDTCLATVALADAGV--PDHPQMIKAADWMLAEQIV--RPGDWVVRPDLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVAHP-
----DATRVDKAVRRAVDWNVGMQSKNGAWGAFDADNTSPF---PNPFSDFGEV-IDPPSADVTAHVVEMLAEEG-------LA-HHPRTRRGIEWLLKN
QEGNGSWFGRWGVNYVYGTGAVVPALVAAGLPAS-HPAIRRSVSWLGQVQN-DGGWGEDLRSYQDWHGRG--HSTASQTAWALLALLAAGE--ET-EQVR
RGIAYLVETQTEDGTWDEPWFTGGFPWDFTINYHLYRQVFPVTALGRYLNGTGPG--
>tr|D9V481|D9V481_9ACTO Squalene-hopene cyclase OS=Streptomyces sp. AA4 GN=SSMG_02728 PE=4 SV=1
---------------------------------------------------------------------------------------------AADTVAA
AVQFLRREQDRAGWWKGELATNVTMDAEDLLLRHFLGILTP-Q--I-AEESARWIRSQQRADGTWANFPDGPADLSTTVEAWVALRLAGDPADAP---WL
ATAAEWIREHGGIEATRVFTRIWLAMVGQWSWDDLPSLPPELIFLPSWFPLNVYDFACWARQTIVPLTIVGTLRPARKL-PF-----AELRTGKRPK-P-
----------R----GVF--QNLDTAL-HA----YAKL-LNPVRKLALKQAAEWILAREADGSWGGIQPPWVILALHLLYSLDH--PALKAGIAGLDGFT
IREKWVRRLEAC-QSPVWDTALAMTALLDAGV--SGDESLVRAAEWMLGEEIR--VPGDWAVRPSLKPGGFAFEFANDGYPDTDDTAEVVLALRRMGKP-
----DHLRIREAVDRSVAWLEGMQSSDGGWGAFDADNTQVL---TTPFCDFGAV-IDPPSADVTAHVVEMLAAEG-------KA-DTRECRRGIRWLWDN
QEADGSWFGRWGANYVYGTGAVVPALVAAGVPGT-DPRIRRAVRWLAEHQN-DGGWGEDLRSYDDWAGRG--DSTPSQTAWALLALLAAGE--ES-TVVA
RGVEWLCERQRPDGGWDEDKHTGGFPGDFYLSYHLYRVVFPLSALGRYVRGGS----
>tr|H0KBN6|H0KBN6_9PSEU Squalene-hopene cyclase OS=Saccharomonospora azurea SZMC 14600 GN=SZMC14600_22795 PE=4 SV=1
---------------------------------------------------------------------------------------------VRRCVDS
ARDHLLSLQHSQGWWKGELETNVTMEAEDLLLRQFLGISDP-R--V-TEETARWIRSRQREDGTWATFHDGPADVSTTVEAYTALRLAGDPLDAA---HL
RRAREYILDSGGIEATRVFTRIWLALFGQWSWRELPVLPPELVLLPDWFPLNIYDWACWARQTVVPLTIVGAARPARQL-GF-----RELRTGAATSAD-
----------S----GLF--HGLDAVL-HR----LERL-VKPLRATALDRAEKWILDREADGGWGGIQPPWVILALHLRYPIDH--PVMSKALDGLDGFT
IREEWVRRLEAC-QSPVWDTALAMTALLDAGT--PDHPALVSAADWILGEEIR--VGGDWQVRPDLEPSGWAFEFANDCYPDTDDTAEVVLGLRRVRHP-
----EPERVDASVRRATEWLIGMQCSDGGWGAFDADNTRTL---CEPFCDFGAV-IDPPSADVTAHVVEMLAARG-------LA-DSEAARRGVRWLLDA
QEADGSWFGRWGANHVYGTGAVVPALIACGIPAD-HEAIRAAVHWLTAHQN-DGGWGEDLRSYVDWVGRG--ASTASQTAWALLALLAAGE--G--AVVT
RGVEWLVETQRPDGGWDQPQYTGGFPGDFYINYHLYRLVFPITALGRYVESSRDV--
>tr|Q82ML0|Q82ML0_STRAW Squalene-hopene cyclase OS=Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-46
---------------------------------------------------------------------------------------------AARATQR
ATDFLLSRQDAEGWWKGDLETNVTMDAEDLLLRQFLGIQDE-K--T-TRAAGLFIRGEQRADGTWATFYGGPGDLSATIEAYVALRLAGDGPDEP---HM
AKASAWIRERGGIASARVFTRIWLALFGWWKWDDLPELPPELIYFPKWMPLNIYDFGCWARQTIVPLTVVSAKRPVRPA-PF-----DELHADANDNPAK
----------P----GLF--QRLDVAL-HT----YRKV-PRRLRKAAMNTAARWIIERENDGCWGGIQPPAVVIALYLLYDLEH--PVMREGLASLDRFA
VWRD-ARMIEAC-QSPVWDTCLATIALADAGV--PDHPQLVRAADWMLGEEIV--RPGDWAVRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRVKHH-
----DPERLDNAIRRGVRWNLGMQSKDGGWGAFDVDNTSPF---PNPFCDFGEV-IDPPSADVTAHVVEMLAFEG-------LS-HDPRTRRGIQWLLSA
QEANGSWFGRWGVNYVYGTGSVVPALVAAGLPAS-HPAIRRAVTWLETVQN-DGGWGEDLRSYPEWSGKG--ASTASQTGWALLALLAAGE--ES-KAVE
RGIEWLAQTQRPDGSWDEPYFTGGFPWDFSINYHLYRQVFPLTALGRYVNGEPLV--
>tr|I2N9L8|I2N9L8_9ACTO Squalene/oxidosqualene cyclase OS=Streptomyces tsukubaensis NRRL18488 GN=STSU_04236 PE=4 SV=1
---------------------------------------------------------------------------------------------ARRAVNR
AVDHLLARQDAEGWWKGDLETNVTMDAEDLLLRQFLGIGDR-A--V-TEASARFIRGRQRADGTWATFYGGPGELSATVEAYVALRLAGDLPGDP---HM
ARAAAWVREQGGIAATRVFTRIWLALFGWWRWEDLPVVPPELIFLPKWFPLNIYDFGCWARQTIVPLTVVSARRPVRPA-PF-----DELHTDPLLNPPR
----------P----GFF--QRADRAL-HR----YHRV-PRRVRESAIAAASRWIVERENDGCWGGIQPPAVLIALHLLYDLGH--PVMRAGIESLDRFA
IWEKPVRMIEAC-QSPVWDTCLATVALADAGL--ADHPALVRAADWMLGEEIV--RPGDWAVRPGLAPGGWAFEFHNDNYPDIDDTAEVVLALRRVAHP-
----DPARVDAAVARAGRWTLGMQSRDGGWGAFDADNTSPF---PNPFCDFGEV-IDPPSADVTAHVLEMLAYEG-------RA-HTPRARRAVDWLLAH
QEPGGAWFGRWGVNYVYGTGSVVPALVAAGIPAA-HPALRRAVDWLRSVQN-DGGWGEDLRSYDHWAGQG--SSTPSQTAWALLALLAAGE--DS-ESAE
RGVRWLVEAQRDDGGWDEPYFTGGFPWDFSINYHLYRQVFPLTALGRYVHGEPPV--
>tr|D9X7G3|D9X7G3_STRVR Squalene-hopene cyclase OS=Streptomyces viridochromogenes DSM 40736 GN=SSQG_06762 PE=4 SV=1
---------------------------------------------------------------------------------------------AVRAARR
ATDFLLSRQDAQGWWKGDLETNVTMDAEDLMLRQFLGVLDE-K--T-AQAAALFIRGEQREDGTWASFYGGPGELSTTIEAYVALRLAGDAPDSP---HL
AKASAWIREQGGIAAARVFTRIWLALFGWWKWEDLPELPPELIWFPKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPA-PF-----DELHTDPARNPPR
----------P----GAF--QRMDKGL-HA----LRKV-PRGLRRAAMNAAARWIIERENDGCWGGIQPPAVIIALHLLYDLQH--PVMREGLASLDRFA
VWRE-ARMVEAC-QSPVWDTCLAAIALVDAGL--PDHPQLVKAADWMLGEEIV--RPGDWSVRPGLPPGGWAFEFHNDNYPDIDDTAEVILALRRITHH-
----DPVRVDKAVGRGVRWTLGMQSKNGAWAAFDVDNTSPF---PNPFCDFGEV-IDPPSADVTAHVIEMLAVEG-------LA-HDPRTRRGIEWLLAE
QEPDGSWFGRWGVNYVYGTGSVVPALVAAGLPGA-HPAIRRAVSWLESVQN-DGGWGEDLRSYKYWSGRG--ASTASQTAWALMALLAAGE--DS-KAVE
RGVEWLAATQREDGSWDEPYFTGGFPWDFSINYHLYRQVFPLTALGRYVHGEPFA--
>tr|A0A0B5DQI4|A0A0B5DQI4_9ACTO Squalene-hopene cyclase OS=Streptomyces nodosus GN=SNOD_28690 PE=4 SV=1
---------------------------------------------------------------------------------------------AEHAMRR
ATDFLLSRQDAQGWWKGDLETNVTMDAEDLLLRQFLGIRDE-R--T-THAAALFIRGEQRDDGTWAAFYGGPGELSTTIEAYVALRLAGDAPHEP---HM
AKASAWIREQGGVAASRVFTRVWLALFGWWRWEDLPEMPPELIYFPKWMPLNIYDFGCWARQTIVPLTVVSALRPVRPA-PF-----DELHTDADDNPAR
----------S----GVF--QRLDKGL-HG----YRRV-PRRLRRAAMNAAARWIVERENDGCWGGIQPPAVIIALHLLYDLQH--PVMREGIASLDRFA
VWRD-ARMIEAC-QSPVWDTCLATIALADAGV--PDHPQLVKAAEWMIEEQID--RPGDWSVRPQLPPGGWGFEFHNDNYPDIDDTAEVVLALRRVGHR-
----DRERAEQAIARGVRWNLGMQSRNGAWAAFDVDNTSPF---PNPFSDFGEV-IDPPSADVTAHVVEMLAVEG-------LA-HDPRTRRGIEWLLSE
QEADGSWFGRWGVNYVYGTGSVVPALVAAGVPGA-HPAIRRAVGWLEGVQN-DGGWGEDLRSYAYWSGRG--ASTASQTAWALLALLAAGE--ES-KAVE
RGIEFLARTQNEDGSWDEPYFTGGFPWDFSINYHLYRQVFPLTALGRYVNGEPFT--
>tr|V6KJG5|V6KJG5_STRNV Squalene-hopene cyclase OS=Streptomyces niveus NCIMB 11891 GN=M877_04840 PE=4 SV=1
---------------------------------------------------------------------------------------------ARRATAR
SVEHLLGQQDAQGWWKGDLETNVTMDAEDLLLRQFLGVQDA-G--T-TEAAGRFIRGEQRADGTWATFYGGPGELSTTIEGYVALRLAGDRPDDP---HM
ARAAAWIREQGGVAESRVFTRIWLALFGWWKWDDLPEVPPELIFLPKWFPLNIYSFGCWARQTIVPLTIVSALRPVRPA-PF-----DELHTDVSHNPTK
----------P----GIF--QRIDKAL-HL----YHKV-PRAVRRTAMNAAARWIVERENDGCWGGIQPPAVVIALHLLYDLKH--PVMRAGLESLDRFA
VWRE-SRMIEAC-QSPVWDTCLATIALADAGV--RDHPALVKAAEWMLDEQIV--RSGDWAVRPGLAPGGWAFEFHNDNYPDIDDTAEVILALRRVAHP-
----DTARMDTAVRRGARWTLGMQSKNGAWGAFDADNVSPF---PNPFCDFGEV-IDPPSADVTAHVVEMLAYEG-------LG-GHPDTRRGIEWLLAE
QEADGAWFGRWGVNYVYGTGSVVPALVAAGIPVT-HPAIRRAVGWVESVQN-DGGWGEDLRSYREWIGHG--ASTASQTAWALLALLAAGR--ET-PAVE
RGVAWLAAAQREDGSWDEPYFTGGFPWDFSINYHLYRQVFPLTALGRYVNGEPLP--
>tr|B4VCS3|B4VCS3_9ACTO Squalene-hopene cyclase OS=Streptomyces sp. Mg1 GN=SSAG_05498 PE=4 SV=1
---------------------------------------------------------------------------------------------VQDATAR
AIRNLLGRQDPAGWWKGDLETNVTMDAEDLLLRQFLGIRDE-A--V-TQAAALFIRREQREDGTWATFHGGPPELSATIEAYVALRLAGDAPDAP---HM
ATASAWIRAHGGLAAARVFTRIWLALFGWWDWENLPELPPELVLLPPWVPLNIYDFGCWARQTIVPLTVVSAMRPVRPA-PF-----DELHTDARVVPPR
----------R----GAF--QWMDRAL-HV----YRRF-PRRLREAAMASAGRWIIERENDGCWGGIQPPAVVIALHLLYDLGH--PVMRAGLESLDRFA
VWRE-SRMIEAC-QSPVWDTCLAAIALADAGV--RDHPALVKAADWMLGEEIV--RTGDWAVRPGLAPGGWAFEFHNDTYPDIDDTAEVVLALRRIRHP-
----DPARVEAAIARGVSWNLGMQSRGGAWGAFDADNTSPF---PNPFCDFGEV-IDPPSADVTAHVVEMLAAEG-------RA-ADPRTRRGIAWLLAE
QEPEGPWFGRWGTNYVYGTGSVVPALTAAGLSPG-HPAIRRAVLWLESVQN-DGGWGEDQRSYQDWAGKG--ESTPSQTAWALMALLSAGE--DA-KTVE
RGIAYLVETQLADGGWDEPHFTGGFPWDFSINYHLYRHVFPLTALGRYLYGEPFG--
>tr|F3NGG4|F3NGG4_9ACTO Squalene-hopene cyclase OS=Streptomyces griseoaurantiacus M045 GN=SGM_2228 PE=4 SV=1
---------------------------------------------------------------------------------------------ATRAMLR
ATDFLLARQDAQGWWKGDLETNVTMDAEDLLLRQFLGIRDE-R--T-TRASALFIRGEQREDGTWATFHGGPGELSTTIEAYVALRLAGDAPDAP---HM
AKASAWVRARGGIASARVFTRIWLALFGWWKWEDLPELPPELIYFPTWFPLNIYDFGCWARQTIVPLTIVSAKRPVRPA-PF-----DELHVDPDRNPPR
----------P----GAF--QRLDRAM-HR----VRKV-PRRLRRAAMNSAARWIVERENDGCWGGIQPPAVVIALYLLYDLEH--PVMRAGLQSLDRFA
VWRE-ARMIEAC-QSPVWDTCLATIALADAGL--PDHPQLVKAADWMLGEQVV--RPGDWSVRPGLPPGGWAFEFHNDNYPDTDDTAEVVLALRRVAHH-
----DPERMERAIGRGVAWNLGMQSKNGAWGAFDVDNTSRF---PNPFCDFGEV-IDPPSADVTAHVVEMLAVEG-------LA-HDPRTRRGIEWLLAE
QEEDGSWFGRWGVNYVYGTGSVVPALAAAGLPGS-HPALRRAVAWLESVQN-DGGWGEDLRSYHEWSGRG--ESTASQTAWALMALLAAGE--DS-KAVE
RGISWLAATQREDGSWDEPQFTGGFPWDFSINYHLYRQVFPLTALGRYVHGEPFS--
>tr|A0A0B5ICN8|A0A0B5ICN8_9ACTO Squalene-hopene cyclase OS=Streptomyces vietnamensis GN=SVTN_31635 PE=4 SV=1
---------------------------------------------------------------------------------------------AARAAER
AVEHLLARQDPAGWWKGDLETNVTMDAEDLLLRQFLGILDA-D--T-TRAAALHIRREQREDGAWATFHGGPGELSATVEAYVALRLAGDPPEAP---HM
ARASAWVRARGGIAAARVFTRIWLALFGWWRWEDLPELPPELLFLPKWFPLNIYDFGCWARQTIVPLTVVSAKRPVRPA-PF-----DELHTDPARNPPR
----------P----GIF--QRLDKAL-HV----YHRF-PRGVRTTAMNIAARWIVERENDGCWGGIQPPAVVIALHLLYDLKH--PVMRAGLESLDRFA
VWRE-SRMIEAC-QSPVWDTCLATIALADAGL--RDHPALVKAVDWMLDEEIT--RTGDWAVRPGLPPSGWAFEFHNDNYPDIDDTAEVLLALRRVKHP-
----DPARVEAAIARGARWTLGMQSKNGAWGAFDADNTSIF---PNPFCDFGEV-IDPPSADVTAHVVEMLGYEG-------MV-QDPRARRGIEWLLAE
QEPHGAWFGRWGVNHVYGTGSVLPALAAAGLPAS-HPAIRRAVDWLGSVQN-DGGWGEDLRSYREWIGHG--TSTASQTAWALIALLAAGE--DS-EPVR
RGIAWLAGTQREDGSWDEPQFTGGFPWDFSINYHLYRQVFPLTALGRYVYGEPSP--
>tr|A0A024YX55|A0A024YX55_9ACTO Squalene-hopene cyclase OS=Streptomyces sp. PCS3-D2 GN=AW27_02455 PE=4 SV=1
---------------------------------------------------------------------------------------------MYEATAR
ATRHLLDRQDPAGWWKGDLETNVTMDAEDLLLRQFLGIRDE-A--T-TYAAALFIRGEQREDGTWATFHGGPPELSATIEAYVALRLAGDPPDAP---HM
SRASAWIRANGGVAAARVFTRIWLALFGWWSWDHLPELPPELVFLPPWVPLNIYDFGCWARQTIVPLTVVSAMRPVRPA-PF-----DELHSDAGRYPAP
----------R----GAF--QRMDKAL-HV----YRRF-PRRLRRAAMGTAARWIVERENDGCWGGIQPPAVVIALHLLYDLGH--PVMRAGLESLDRFA
VRRA-ARMIEAC-QSPVWDTCLAAIALADAGV--RDHPALVKAADWMLGEEIT--RTGDWAVRPGLAPGGWAFEFHNDTYPDIDDTAEVVLALRRIRHP-
----DPVRVDAAIARGVSWNLGMQSKDGAWGAFDADNTSPF---PNPFCDFGEV-IDPPSADVTAHVVEMLAFEG-------RA-GDARTRRGIAWLLDA
QEPDGSWFGRWGTNYVYGTGSVVPALTAAGIAQG-HPAVRRAVHWLESVQN-DGGWGEDQRSYRDWAGKG--ASTASQTAWALMALLAAGE--DG-KAVE
RGIAHLVQTQREDGSWDEPYFTGGFPWDFSINYHLYRQVFPLTALGRYLYGEPSA--
>tr|A0A099D9R0|A0A099D9R0_9ACTO Squalene-hopene cyclase OS=Actinopolyspora erythraea GN=IL38_07205 PE=4 SV=1
---------------------------------------------------------------------------------------------WEEALRA
GRDHLLGLQHEQGWWKGELQTNVTMDAEDLMLRQFLGIREE-K--E-TADAARWIRSQQREDGTWAAFHGGPGELSATVEAYVALKLAGDGVDEE---HM
AAARRWILRCGGIERTRVFTRMWLAMFGQWPWDELPAMPPEIVMLPSWVPLSLADWGCWARQTIVPLTVVNTLRPVREL-GV-----AELRTGGPVRVRE
---------NA----TVF--NALDRAL-HV----YQRH-LRPLRRQAMRRAAEWIVAREADGSWGGIQPPWVLIALHLLYQLDH--PVMRTGIQGLEGFL
IRQETLRRLEAC-QSPVWDTVLTIQALHDAGV--PDDPSIRDAVEFVRAEEIT--VRGDWAVRPELPAGGWAFEFDNDGYPDIDDTAEVLLAFTRTGYV-
----EQDRISAAVDRGRRWLRGMQSRGGGWGAFDADNTRWL---VNPFCDFGAV-IDPPSADVTAHVVEALAHLG-------DT-DDRVVRDGVRWLFEQ
QENDGSWYGRWGANHVYGTGAVVPALVSAGIPAE-HCALRQAVRWLERHQN-DGGWGEDLRSYTDWIGRG--ESTPSQTAWALLALLAVGR--DT-DPVR
RGVAFLAETQREDGSWEEPQFTGGFPGDFYINYHLYRQLFPVTALGRYRQAVTVE--
>tr|C7MXN7|C7MXN7_SACVD Squalene-hopene cyclase OS=Saccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101) GN=Svir_230
---------------------------------------------------------------------------------------------VRSCVSS
ARQYLLSLQHEEGWWKGELDTNVTMEAEDLLLRQFLGISDE-Q--V-TQETARWIRSCQREDGTWATFHGGPPDLSTTVEAYVALRLAGDAMDAA---HL
RKAREYILDSGGIESTRVFTRIWLALFGEWPWSRLPVLPPEMMLLPDWFPLNIYDWASWARQTVVPLTIVGSLRPTRDL-GF-----RELRTGIQRDLE-
----------S----GVF--HGLDSVL-HR----LEKL-LKPLRKVALARAEQWILDRESDGGWGGIQPPWVILALHLRYPLDH--PVLRKALDGLDGFT
IRHRWIRKLEAC-QSPVWDTALAMTALLDSGT--PNDPALVRAADWILRQEIR--VSGDWRVRPALEPSGWAFEFANDHYPDTDDTAEVVLGLQRVRHP-
----EPHRVNAAVERATAWLVGMQSSDGGWGAFDADNTRTL---CEPFCDFGAV-IDPPSADVTAHIVEMLAARG-------MA-DSESARRGVRWLLEH
QEVDGSWFGRWGANHVYGTGAVVPALVACGISPQ-HEAVRAAVQWLVAHQN-DGGWGEDLRSYVDWVGRG--TSTPSQTAWALLALLAAGE--G--EVVR
RGVEWLMAAQRPDGGWDEPQYTGGFPGDFYISYHMYRIVFPLTALGRYLGRGGDV--
>tr|D9VRF9|D9VRF9_9ACTO Squalene-hopene cyclase OS=Streptomyces sp. C GN=SSNG_05931 PE=4 SV=1
---------------------------------------------------------------------------------------------VREAVDR
ATAELLARQDPAGWWKGDLQTNVTMDAEDLLLRQFLGIRDE-A--V-TRAAALFIRGEQQGDGTWATFHGGPPELSATIEAYVALRLAGDPPDAP---HM
TRASAWIRAHGGIAAARVFTRIWLALFGWWSWDRLPELPPELVFLPPWVPLNIYDFGCWARQTIVPLTVVSALRPVRSA-PF-----DELHTDARDVPAK
----------P----GAF--QRMDKAL-HL----YRRV-PRRLRKAAMAAAGRWIVERENDGCWGGIQPPAVVIALHLLYDLGH--PVMRAGLESLDRFA
VWRE-ARMVEAC-QSPVWDTCLAAIALADAGL--PDHPALVRAADWMLGEEIR--RPGDWAVRPGLAPGGWAFEFHNDNYPDIDDTAEVVLALRRIRHP-
----QPGGVEAAIARGVSWTLGMQSKNGAWGAFDADNTSPF---PNPFCDFGEV-IDPPSADVTAHVVEMLAAEG-------RA-ADPRARRGIAWLLAE
QEPDGPWFGRWGTNYVYGTGSVVPALTAAGIAPS-HPAVRRAVRWLESVQN-DGGWGEDQRSYRDWAGKG--ASTASQTAWALMALLSAGE--DG-DAVA
RGLAYLVETQRPDGTWDEPYFTGGFPWDFSINYHLYRQVFPLTALGRYLHGEPFG--
>sp|P33247|SQHC_ALIAD Squalene--hopene cyclase OS=Alicyclobacillus acidocaldarius subsp. acidocaldarius (strain ATCC 27009 / DSM 446 / JCM 5260 / NBR
---------------------------------------------------------------------------------------------YARTLDR
AVEYLLSCQKDEGYWWGPLLSNVTMEAEYVLLCHILDRVDR-D--R-MEKIRRYLLHEQREDGTWALYPGGPPDLDTTIEAYVALKYIGMSRDEE---PM
QKALRFIQSQGGIESSRVFTRMWLALVGEYPWEKVPMVPPEIMFLGKRMPLNIYEFGSWARATVVALSIVMSRQPVFPL-PEA---RPELYETDVPRRR-
----------G----WIF--DALDRAL-HG----YQKL-VHPFRRAAEIRALDWLLERAGDGSWGGIQPPWFLIALKILM-TQH--PAFIKGWEGLELYG
VELDGGWMFQAS-ISPVWDTGLAVLALRAAGL--PDHDRLVKAGEWLLDRQIT--VPGDWAVRPNLKPGGFAFQFDNVYYPDVDDTAVVVWALNTLRLPD
----E-RRRRDAMTKGFRWIVGMQSSNGGWGAYDVDNTSDL---PNPFCDFGEV-TDPPSEDVTAHVLECFGSFG-------YDDAWKVIRRAVEYLKRE
QKPDGSWFGRWGVNYLYGTGAVVSALKAVGIDTR-EPYIQKALDWVEQHQN-DGGWGEDCRSYEDYAGKG--ASTPSQTAWALMALIAGGR--ES-EAAR
RGVQYLVETQRPDGGWDEPYYTGGFPGDFYLGYTMYRHVFPTLALGRYKQAIERR--
>tr|G0Q6I7|G0Q6I7_STRGR Squalene-hopene cyclase OS=Streptomyces griseus XylebKG-1 GN=SACT1_1081 PE=4 SV=1
---------------------------------------------------------------------------------------------ARRAAER
SVEHLLGRQDEQGWWKGDLATNVTMDAEDLLLRQFLSIQDP-E--T-TRAAALFIRGEQLGDGTWNTFYGGPGDLSATIEAYVALRLAGDRPDEP---HM
ARAAGWIRDQGGIAAARVFTRIWLALFGWWKWDDLPELPPELMFFPKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPA-PF-----DELHTDPDHNPPR
----------K----GLF--QRLDKGL-HL----YHKV-PRPLRRVAMNLAARWIIERENDGCWGGIQPPAVVIALHLLYDLDH--PVMKAGLASLDRFA
VRRE-ARMIEAC-QSPVWDTCLATIALADAGL--RDHPALVKAADWMLAEEIT--RPGDWSVKPELAPGGWAFEFHNDNYPDIDDTAEVVLALRRVRHP-
----DPARLQAAIDRGVRWNLGMQSRNGAWGAFDADNTSPF---PNPFCDFGEV-IDPPSADVTGHVVEMLAVEG-------LA-SHPRTREGIEWLLAE
QEACGAWFGRWGVNYVYGTGSVVPALITAGLPAG-HPAIRRAVAWLESVQN-DGGWGEDLRSYQEWIGHG--ESTASQTAWALLALLAAGR--DT-RPVA
RGVTWLTEAQQADGSWDEPYFTGGFPWDFSINYHLYRQVFPLTALGRYVHGDPFA--
>tr|H5X1Q4|H5X1Q4_9PSEU Squalene-hopene cyclase OS=Saccharomonospora marina XMU15 GN=SacmaDRAFT_2676 PE=4 SV=1
---------------------------------------------------------------------------------------------VLETVQR
ARSYLLSLQHEEGWWKGELETNVTMDAEDLLLRRFIGVDDE-Q--T-TAEAARWIRSCQRDDGTWANFHDGPADLSTTVEAYTALRLAGDPAEAP---HL
RRAREYILDSGGLEATRVFTRIWLAMFGEWSWNDLPVLPPELMLLPEWFPLNIYDWACWARQTVVPLTIVGSARPSREL-GV-----RELRTGRRNGPD-
----------S----GAF--HGLDAVL-HR----LEKF-VKPLRGFALAKAERWILDRESDGGWGGIQPPWVILALNLRYSVEH--PAIRKALDGLEGFT
IREHWVRRLEAC-QSPVWDTALALTALLDSGL--SDDPALLRAADWIMREEIR--TDGDWRVRPRLEPSGWAFEFANDNYPDTDDTAEVVLAMNRIDHP-
----QPRRLASVLERATAWVAGMQSADGGWGAFDADNTQTL---CEPFCDFGAV-IDPPSADVTAHVVEMLAARG-------LA-DSEPVRRGVRWLLDN
QEADGSWFGRWGANYVYGTGAVVPALVACGLPRT-HKAVRAAIGWLVAHQN-DGGWGEDLRSYVDWIGKG--TSTASQTAWALLAMLAAGE--G--QAVR
RGVDWLARTQRADGGWDEPQFTGGFPGDFYINYHLYRLVFPLTALGRYVEVTRHE--
>tr|A0A077LXT3|A0A077LXT3_9MICO Squalene--hopene cyclase OS=Tetrasphaera japonica T1-X7 GN=shc PE=4 SV=1
---------------------------------------------------------------------------------------------VRTALDA
AVALLRSVQHKDGWWKGELATNVTMDAEDLMLRHFLGIATR-R--T-DEETARWIRSQQADDGSWATFAGGPGELSTTVEAWVALRMAGDDPGAD---HL
CRAAAYVRGAGGVERARVFTHLWLSMFGLWSWDDCPSLPPEMIFLPRRAPLNIYDWACWARQTIVPLTIVSALRPVRPV-PF-----GDLRTGATAP-R-
----------A----GVF--QRLDGVL-HA----YARR-VGFLRRAAMRQAAEWILAREADGGWGGIQPPWVIIALHVLYPVDH--PAVRAAIAGLDGFT
ICEDPVRRLEAC-QSPVWDTGLALAALLDCGV--ADDPAVLRATDWLLEEQIA--APGDWQVRPDLPSGGWAFEFANDGYPDTDDTAEIVMAMRRVAHP-
----DAARLGRALDRAVTWTTGMQSADGGWGAFDADNAHTL---AEPFCDFGAV-IDPSSADVTAHIVEMLATEG-------RA-GEEACRRGVRWLLDA
QEADGSWFGRWGANHVYGTGAVVPALVAAGISPQ-AAPVRAAVRWLVDHQN-DGGWGEDLRSYADWIGRG--DSTPSQTAWALLALIAAGE--S--TAVH
RGIGHLLETQRPDGGWNEDRYTGGFPGDFYISYHLYRLVFPIWALGRYLRSRP----
>tr|A0A0C2BCW0|A0A0C2BCW0_9ACTO Squalene-hopene cyclase OS=Streptomyces sp. 150FB GN=QR77_36110 PE=4 SV=1
---------------------------------------------------------------------------------------------AERATAR
SVEHLLGQQDAQGWWKGDLATNVTMDAEDLLLRQFLGVQDA-H--T-TEASALFIRGEQRADGTWATFHEGPGELSATIEAYVALRLAGDAPEAP---HM
ARASAWVREQGGIAASRVFTRVWLALFGWWKWDDLPELPPELIFFPKWFPLNIYDFGCWARQTIVPLTIVSAKRPVRPA-PF-----DELHTDPDDNPAK
----------P----GAF--QRLDKFL-HV----YHKF-PRKLRRTAMNAAARWIIERENDGCWGGIQPPAVVIALHLLYDLDH--PVMRAGLESLDRFA
VWRE-ARMIEAC-QSPVWDTCLAAIALADAGL--SDHPALVKAADWMLGEQIV--RPGDWSVRPGLVPGGWAFEFHNDNYPDIDDTAEVILALRRVRHP-
----SPARLDAAIERGTRWTLGMQSRNGAWAAFDADNTSPF---PNPFCDFGEV-IDPPSADVTGHVVEMLAYEG-------KA-HHPDTRRGVEWLLAE
QETTGAWFGRWGVNYVYGTGSVVPALTAAGLPVS-HPAIRRAVTWLESVQN-DGGWGEDLRSYREWIGHG--ASTASQTAWALLALLSAGE--ET-KAVE
QGIAYLSETQREDGSWDEPYFTGGFPWDFSINYHLYRQVFPLTALGRYVHGEPFA--
>tr|W5W8E3|W5W8E3_9PSEU Uncharacterized protein OS=Kutzneria albida DSM 43870 GN=KALB_4044 PE=4 SV=1
---------------------------------------------------------------------------------------------VLEAVHR
ARNRLLSLQTPLGWWKGELQTNVTMDAEDLLLRQFLGIRDE-Q--V-TTESARWIRSQQREDGTWATFHDGPGDLSTTAEAYTALKLAGDPADAR---HM
RQARQFVLDSGGLERSRVFTRIWLALFGEWSWNRLPVLPPEMILLPSWCPLNIHDWGCWARQTAVPLTVVSATRPCRDL-GV-----RELRSGSPAQAE-
----------R----GAF--HHLDRVL-HA----YERL-AKPLRRLSLRKAEQWILDREADGSWGGIQPPWVVLALHLLYSPHH--QVLQRALSGLEGFV
IRERWVRRLEAC-QSPVWDTALALTALLDTGT--PDAPEVLRAVDWLLSQEVR--KSGDWTVRPGLRPSGWAFEFANDTYPDIDDTAEVVLALRRVRHP-
----DPSEVAQAIHRASRWVQGMQCIDGGWAAFDADNTRTL---CEPFCDFGAV-IDPPSADVTAHVLEMLAMLG-------DT-GSAQVRQAVRWLLEH
QEPAGSWFGRWGANHVYGIGAVVPALVAAGLPTS-HEALRAAVRWLGEHQN-DGGWGEDLRSYRDWIGRG--ESTASQTAWALLALLATGE--G--QPLL
RGVDWLVATQRADGSWDEPQFTGGFPGDFYINYHLYRLVFPISALARFLEANDAQ--
>tr|J9HMR6|J9HMR6_9BACL Squalene-hopene cyclase OS=Alicyclobacillus hesperidum URH17-3-68 GN=URH17368_1806 PE=4 SV=1
----------------------------------------------------------------------------------------------MQTLDN
GVEYLLSRQHEEGYWWGTLLSNVTMEAEYVLLCHCLGKVDK-G--R-LEKIKTYLLHEQREDGTWAQYPGGPQDLDTTIEAYVALKYIGLSPDDE---RM
QKALAFIQSQGGIESARVFTRLWLAVVGEYPWRKLPVVPPEIMFLGKNMPLNIYDFGSWARPTIVALTIVMSRRAVFPL-PAA---KPELFETNVPRRR-
----------A----SLF--LSIDKLL-QG----YQNG-FHPFRKAAEQRAIEWLIEHAGDGSWGGIQPPWFLLALKVMM-TNH--PAFIKGWEGLELYG
LELEGGWMFQAS-ISPVWDTGLSILALRAAGL--ADEPALVKAGKWLLDHRIA--TKGDWAVRPNAKPGGWAFQFDNPHYPDVDDTAVVVWALNGLKLPN
----E-AERRDAMTAGFRWLTAMQSSNGGWGAYDVDNNKEL---PNPFCDFGEV-IDPPSEDVTAHVLECFGSFG-------YDEAWKVVARAVNYLKRE
QKPDGSWYGRWGVNYIYGIGAVVPALKSVGVDMK-EPFVQKALDWLVAHQN-DGGWGEDCRSYVDFAGVG--PSTPSQTAWALMALIAGGR--QA-DAVS
RGVAYLVRTQRSDGGWDEPYYTGGFPGDFYLGYTLYRHIFPVMALGRYKDALGRL--
>tr|L0DPP5|L0DPP5_SINAD Squalene-hopene cyclase OS=Singulisphaera acidiphila (strain ATCC BAA-1392 / DSM 18658 / VKM B-2454 / MOB10) GN=Sinac_7166 PE=4
---------------------------------------------------------------------------------------------LGLGIAE
SLAWLQADQKAAGFWVGAVESNSCMEAEWILAMHVLGVSDDP----KLPGVVQAILNQQREDGAWEVYQGEGGDINTTVECYAALRAAGEDPESR---PL
REARAWIQQHSGMSRLRNFTKYWLALIGEWPWSETPTLPPELIYLPPWMPFNIYQFATWARGTILPLTILSARKATRPL-PPR---RDELFPEGR-NH--
-----------PDHRGPF--YLIDRML-RW----YSNS-IQPGRETAIRLCLEWIIKHESDGSWAGIQPPWILMALNQEYPLDH--PVVRAGLDGFNSYW
SYERA-TYLQAS-ESPVWDTVLSLQAILDCGCQLKDSPSMEAAVQWLLDHQIT--FPGDWKVSPKLTGGGWAFQRTNRHYPDIDDTAVALLVLHRLREQS
P--EPTSRFDDAIEKATHWLLGMQCSNGGWGAYDRDNTHAW---LTPFSDFGEL-IDPPSSDVTAHVIEALAAGG-------RTLDDPAVARAVRFLRAE
QEDDGSWFGRWGVNHIYGTAAVLPALRAVGID--REPWIRQGAEWLASRQNPDGGWGETCASYMDLRGVG--TSTASQTGWALMGLLAIETRGF-DKIIR
RGITFLLDR-QVSGTWNEPEYTGGFPGGFMINYNLYRHYFPLMALGRAKSHFGSV--
>tr|T0DEU9|T0DEU9_9BACL Uncharacterized protein OS=Alicyclobacillus acidoterrestris ATCC 49025 GN=N007_04615 PE=4 SV=1
---------------------------------------------------------------------------------------------VQATLEA
GVAHLLRRQAPDGYWWAPLLSNVCMEAEYVLLCHCLGKKNP-E--R-EAQIRKYIISQRREDGTWSIYPGGPSDLNATVEAYVALKYLGEPASDP---QM
VQAKEFIQNEGGIESTRVFTRLWLAMVGQYPWDKLPVIPPEIMHLPKSVPLNIYDFASWARATIVTLTIVMNRRPVTPL-PDA---KPELFEAKRPKRR-
----------S----GFF--VALDKFL-KA----YNKW-IQPGRKSGEQKALEWILAHEADGCWGGIQPPWFLLALKCLM-TDH--PAFVKGFEGLEAYG
VHTSGGWMFQAS-ISPIWDTGLTVLALRSAGL--PDHPALIKAGEWLVSKQIL--KDGDWKVRRKAKPGGWAFEFHCENYPDVDDTAMVVLALNGIQLPD
----E-GKRRDALTRGFRWLREMQSSNGGWGAYDVDNTRQL---TNPFCDFGEV-IDPPSEDVTAHVLECFGSFG-------YDEAWKVIRKAVEYLKAQ
QRPDGSWFGRWGVNYVYGIGAVVPGLKAVGVDMR-EPWVQKSLDWLVEHQN-DGGWGEDCRSYDDLAGQG--VSTPSQTAWALMALIAGGR--ES-DAVL
RGVTYLHDTQRADGGWDEEVYTGGFPGDFYLAYTMYRDIFPVWALGRYQEAMQRI--
>tr|A0A098GBW4|A0A098GBW4_9GAMM Squalene--hopene cyclase OS=Legionella fallonii LLAP-10 GN=shc PE=4 SV=1
---------------------------------------------------------------------------------------------LDIVIKR
ATDYALGIQHQEGYWIAPLDSNSTMEAEFLLLLYFLGIHDEV----RQQKIVNHILKHQQEDGSWSLYFQGSGDLSTTVECYFALMLSGVSKDAP---NM
KLAREFIIAKGGIAKVRVFTQIWLALFGQWSWQQIPTLLPEIIFLPSWFPFNVYAFASWARATVVPLTIVMAERPVCAI-PNC---ATDLFLQD------
--------------AVIF--KVIEKGF-KL----YERMPWKPGRRLAIKKSIQWIIDHEADGSWGGIQPPWVLIALKLTHSLEH--PVMRKGIDGFDSFS
--IEETMQVQAC-VSPVWDTSLMINALKEVGVES-SHPQIQSACRWLIKKQIL--VGGDWSINPKLSPGGWAFEFENANYPDIDDTAEVLMALWHASLSE
---SENVQCKVAIKTGTQWLLGMQGKNGGWAAFDRENNNFF---LAPFFDFGEI-LDPPSVDVTAHVLEALGMMG-------YTRDNPVIKRALDYIYQE
QEPNGSWFGRWGVNYIYGIGTVLPALRAVGED--TSPTIQKAIQWLLAHQNADGGWGESCASYVDQHGCG--PSTPSQTAWALLALMAVDQYE--HPAVH
KGIDYLCDTMNVQGTWDEDHYTGGFPGGFMINYNLYRHCWPLMALGRYQKGWFGN--
>tr|W9GNN8|W9GNN8_9MICO Squalene-hopene cyclase OS=Intrasporangium chromatireducens Q5-1 GN=N864_17635 PE=4 SV=1
---------------------------------------------------------------------------------------------ARSALDR
SVARLRALQHPEGWWKGELETNVTIEAEDLLVRQFLGIRTD-R--E-TEWTARWIRSKQRGDGSWATFHGGPADLSTTVEAYLALRLAGDRPEDA---HL
VRARDVVRALGGLEQSRVFTRIWLALFGLWPWDRLPAVPVEQVLLPAWVPLSVHDFACWARQTIVPIAVLCALRPHAAL-GF-----TELYAAEPATRPS
---------RG----LLG--QVLDVGL-RV----FERH-PGSLRSRALRRAEAWIIEREADGSWGGIQPPWVLMALRTLRPLDD--PVMQLGLGGWSRFT
VEEPPVRRIEAC-QSPVWDTALALVALGDAGL--RDDPAVARAVDWVLREEIT--TRGDWAVRPHLAAGGWAFEFDNDLYPDVDDTAEVVLGLDRVGAG-
----G----TAPAVRGTDWVLGMQCRDGGWAAFDAENTSTL---PLPFCDFGAV-TDPPSADVTAHVVELLGLTG-------RA-ASPAARAGRDWLLRA
QEPDGSWFGRWGANHVYGTGAALPALVAVGVEPQ-EPAVRRGAAWLEQVQN-DGGWGEDLRSYRDQRGRG--TSTASQTAWALLGLLAAEE--GS-DAVR
RGVQWLVEHQQPDGGWDEPHYTGGFPGDFYINYHLYRLVFPVSALARYVRSLS----
>tr|E3IYF6|E3IYF6_FRASU Squalene/oxidosqualene cyclase OS=Frankia sp. (strain EuI1c) GN=FraEuI1c_5917 PE=4 SV=1
---------------------------------------------------------------------------------------------AAAVLGR
ARDHLLGLQSEAGWWKGELETNVTMDAEDLMLRQFLGILPP-E--L-AAETGRWIRSKQQDDGGWPTFHGGPSDLSTTFEAYVGLRLAGDLPDAP---HM
LAAASFVRAHGGLAATRVFTRIWMALFGEWPWDEVPVLPPELVLLPSWVPLNVYDFGCWARQTVVALTIVGHFRPVRSL-GF-----DELRVAAVR-PD-
---------------GVF--QRLDAGL-RR----YQRH-VKTLRELALRRATEWVLAREADGGWGGIQPPWVIMALHLMYSMDH--PVLVAALDGLETFT
VREQTVRRLEAC-QSPVWDTALAVVALADAGL--DRHPAMRKAGEWLVREEVT--VPGDWRVRPNLEPGGWAFEFANDIYPDVDDTAEVVLAVRRLLGSG
WDPTFAKQARASVERAVNWSVGMRSANGAWGAFDADNVREL---ATPFCDFGEV-IDPPSADVTAHMVEMLADLG-------RA-DHPVTQRAVRWLLDD
QEPGGSWFGRWGVNHVYGTGAVVPALISAGVAAD-HPAIRSAVRWLVAHQH-DGGWGEDLRSYQDWVGRG--EPTASQTAWALLALLAADP--NE--AVG
RGVRWLCDTQLPNGTWDEPYYTGGFPWDFSINYHLYRLVFPLTALGRYVTLTGRS--
>tr|I8QN00|I8QN00_9ACTO Squalene/oxidosqualene cyclase OS=Frankia sp. QA3 GN=FraQA3DRAFT_3535 PE=4 SV=1
---------------------------------------------------------------------------------------------AGVAAAR
ARDHLLALQSDEGWWKGDLETNVTMDAEDLFMKQFLGIRGD-D--E-TEQTARWIRSQQLADGGWPTFYGGPADLSTTIEAYIALRLAGDAVDAP---HM
ARAAELVRAQGGVAASRVFTRIWLAALGQWSWDDVPVIPPELIFLPSWVPLNVYDFACWARQTIVALTIVGSLRPSRDL-GF-----DELKVP--AGRK-
---------------GAF--ERLDKLL-HR----YERR-IKLLRTLALRRATEWVVAREADGCWGGIQPPWVVMALHLMYPLNH--PVIATAFRGMERYV
IRRDPIRQIEAC-QSPVWDTALAVVALADAGV--PDHPAMVKAGRWLVDEEVR--VAGDWAVRPELAPGGWAFEFDNDFYPDVDDTAEVVLALRRLLGAG
HVPRLAAAMRAAAARGVDWSVGMRSSNGAWGAFDADNVRML---TTPFCDFGEV-VDPPSADVTAHIVEMLADLG-------RS-DHPITQRAVQWLLDN
QEPGGSWFGRWGVNHLYGTGAVVPALIGAGVPTD-HPAITAAVRWLLEHQS-EGGWGEDLRSYTDWIGRG--ELTASQTAWALLALLAVDP--SL--AVK
RGVRWLCETQRPDGTWDEPYFTGGFPGDFSLNYHLYRLVFPLTALGRYVSLSGVA--
>tr|F8AZJ1|F8AZJ1_FRADG Squalene-hopene cyclase OS=Frankia symbiont subsp. Datisca glomerata GN=FsymDg_1170 PE=4 SV=1
---------------------------------------------------------------------------------------------VAAAAVR
ARDHLLGLQSDQGWWKGELETNVTMDAEDLLLRQFLGILTP-Q--E-AEETARWIRSQQSEDGTWATFFGGPADLNATFEAYVALRLAGDSPDAP---HM
RSAAEFVRANGGIARTRVFTRIWMALFGEWSWDDLPVMPPELVLLPSWFPLNLYDFACWARQSIMPLTIIGSLRPKRSL-GF-----DELRVDVPP-KP-
---------------GAF--ERLDAVL-HR----YERR-LKLLRRHALRRAAEWIVVREADGCWGGIQPPWVIMALTLLYPMNH--PVIVAGLRGLERFT
VRERMVRRLEAC-QSPVWDTALAVVALRDAGL--ADHPAVVRAARWLADEEVT--VAGDWAVRPALAPGGWAFEFDNDLYPDVDDTAEVVLAIERILGPG
YGPQLAARLRDAGRRGVDWTIGMRSAGGVWGAFDADNTRTL---PTPFCDFGEV-IDPPSADVTAHIVEMLAEVG-------QA-NSPITERAVQWLLDN
QEPGGSWFGRWGVNHIYGTGAVVPALIVAGVPAD-HPSIVRALRWLVEHQR-DGAWGEDLRSYTDWIGRG--EATASQTAWALLALLAADP--SS--AVE
RGVRWLVDTQRPDGTWDEPYYTGGFPGDFSINYHLYRLVFPLTALGRYLSGRSAS--
>tr|A0A062X5L8|A0A062X5L8_9ACTO Squalene cyclase OS=Frankia sp. BMG5.23 GN=BMG523Draft_01765 PE=4 SV=1
---------------------------------------------------------------------------------------------AMTAANQ
ARDHLLGLQSEEGWWKGDLETNVTIDAEHLFMKQFLGIRTE-E--E-TEPIARWVRSQQLADGGWATYYGGPAELSTTVEAYIALRLAGDEPDAP---HM
AAAAALIRSQGGVAAARVFTRIWLATFGEWSWDDVPVLPPELIFLPSWFPLNVYDFGCWARQTIVALTIVGSLRPVRDL-GF-----DEIKVAAPVPPK-
---------------GAF--ERLDAIL-HR----YERR-IKVLRTLALRRATEWVVAREADGCWGGIQPPWIVMALHLMYPLNH--PVIATAFRGMERYI
IRREPTAQIEAC-QSPVWDTALAVVALSDAGV--PDHPAMVRAGRWLVDEEVR--VAGDWAVRPALAPGGWAFEFDNDFYPDTDDTAEVVLALRRLLGGS
HVPQLAGAMRAAAARGVDWSVGMRSSDGAWGAFDADNVRTL---TAPFCDFGEV-VDPPSADVTAHIVEMLADLG-------RS-DHPITRRAVQWLLDN
QEPGGSWFGRWGINHVYGTGAVVPALIAAGVPAD-HPAITAAVRWLLEHQS-DGGWGEDPRSYDDWIGRG--ELTASQTAWALLALLAVDP--SK--AVK
RGVRWLCETQRPDGTWDEPQFTGGFPGDFYLNYHLYRLVFPLTALGRYVTLTGVA--
>tr|A8LER3|A8LER3_FRASN Squalene-hopene cyclase OS=Frankia sp. (strain EAN1pec) GN=Franean1_4758 PE=4 SV=1
---------------------------------------------------------------------------------------------LTRALRL
ATDHLLALQDGTGWWKFDLETNTSMDAEDLLLREYLGIRTT-E--V-TAASARFIRSRQSDDGSWPQYFGGPGELSTTVESYIALRLAGDDASAP---HM
LSAATWVRDHGGVPATRVFTRIWLALFGWWRWEDLPALPPEIMLLPRRAPLNIYSFGSWARQTLVSLTVVSALRPVRPA-PF-----DELYPDGPAAWS-
---------------EIF--LGIDRLL-HV----YHRR-VRSMRNHALRAAERWIIAREADGCFGGIQPPAVIIALRLLYELDH--PVLKAALRALDDYS
VTLP-SRMVEAS-QSPVWDTALAVNALADAGATAADHPALVRAAGWLLGQEVRH-RRGDWAVHPDVPASGWAFEFENDTYPDTDDTAEVLLAL-----RR
VRHPARDELDAAERRAVAWLFGLQSSDGGWGAYDADNTSTI---PYPFADFGAL-TDPPSADVTAHVVELLAEAG-------LG-GDDRTRRGVDWLLDH
QEADGSWFGRWGVNYVYGTGSVMPALRAAGLEPS-HPAMRAGADWLLTHQN-DGGWGEDLRSYTDWSGRG--ESTASQTAWAMLALLTVGD--PVSGALA
RGARWLADHQRPDGSWDEDQFTGGFPGDFYINYHGYRLLWPIMALGRYLRG------
>tr|D3D417|D3D417_9ACTO Squalene-hopene cyclase OS=Frankia sp. EUN1f GN=FrEUN1fDRAFT_4539 PE=4 SV=1
---------------------------------------------------------------------------------------------LAGTLRR
ATRHLLSLQDSTGWWKFDLESNTTMDAEDLLLRDFLGIRTE-S--V-TAASAKFIRSRQLADGSWPQYFGGPGELSITVESYIALRLAGDELSAP---HM
ERAAAWIRRNGGVPATRVFTRIWMALFGWWRWEDLPVLPPEIMLLPDQAPLSIYSFGSWARQTIVPLTIVFALRPVRPA-PF-----DELSVDDPDAGS-
---------------QFF--RWVDAGL-HR----YHHH-IGPLRRHAMRTAERWIIAREADGCFGGIQPPAVIIALRLLYDLAH--PVLKAALEALDDYS
VTLP-ARMIEAS-QSPVWDTALAVNAIVEAGDVIGDDPALLRAADWLLGQEIRD-RSGDWQVHPGLPGGGWAFEFENDTYPDTDDTAEVLLAL-----RH
VRHPAPEKIESATDRTVTWLLGLQSRDGGWGAYDSDNTSTL---VYPFGDFGAL-TDPPSADVTAHVVEALVDAG-------LT-EDPRTQRGVSWLLDH
QESDGSWFGRWGVNHVYGTGSVLPALAAAGLAPS-HPAIGGGVAWLLSRQN-DGGWGEDLRSYSDWIGRG--VSTASQTAWGMLGLLAGEQ--PVAVALA
RAADWLADQQRPDGNWDEDQFTGGFPGDFYLNYNGYRLIWPVLALGRYGHSLRTS--
>tr|Q0RMV6|Q0RMV6_FRAAA Shc2 protein OS=Frankia alni (strain ACN14a) GN=shc2 PE=4 SV=1
---------------------------------------------------------------------------------------------LRETVQR
AAEHLLRLQDPRGWWKFDLETNPTMDAEDLLLREYLGIRTV-E--Q-TEATAKHIRSRRLDDGSWPTYFGGPGELSTTVECYIALRLAGDSPDDE---PL
RRSAAWIRERGGIPATRVFTRIWLALFGWWRWEDLPVLPPEIMFLPPRAPLSIYSFASWARQTIVPLTIVSAARPQCPA-PF-----AELDPDEVPAQSH
GA------AQSPDTRVFF--RGLDAAL-HR----YHRH-IGPLRRHALRTAERWIIAREADGCFGGIQPPAVIIALRLLYDLDH--PVLAAALRSLDAYT
LHRE-SRMIEAS-QSPIWDTALAVLALADAGIDAPVPTALERAADWLLGQEIQH-RRGDWAIHPGVAPGGWAFEFDNDTYPDTDDTAEVVLALHRLNRLR
RLHPTNTRIDAALERSTAWLFALQSRDGGWGAYDSDNASTL---VYPFADFGAL-TDPSSADVTAHVVELLCETG-------RI-RDPRTLRGVDWLLRN
QEADGSWYGRWGVNYVYGTGSVLPALQAAGLPPT-HPAMVAGARWLLSRQN-DGGWGEDIRSYGDWSGRG--LSTPSQTAWAMLGLLATDH--GHADALA
AAARWLTEQQRPDGGWDEEMFTGGFPGFFYLNYHGYRLVWPVMALGRYLHSRQHP--
>tr|G2P4F9|G2P4F9_STRVO Squalene-hopene cyclase OS=Streptomyces violaceusniger Tu 4113 GN=Strvi_2867 PE=4 SV=1
---------------------------------------------------------------------------------------------AREATAR
AVEHLLSRQDERGWWKGDLETNVTMDAEDLMLRQFLGIQDP-D--T-LDAAARFLRSQQGADGTWASFHGGPPELSTTIEAYVALRLAGDEPDAP---HM
AAASAWVRSRGGIAAGRVFTRIWLALFGWWRWEDLPELPPEIIYFPKWLPLNIYDFGCWARQTIVPLTIVSAKRPVRPA-PF-----DELHTDPRRNPPR
----------P----GAF--QRLDRAL-HA----YHKV-FRPLRRAALRSCARWIVERENDGCWGGIQPPAVVIALHLLYDLDH--PVMRAGLESLDRFA
VWRE-SRMIEAC-QSPVWDTCLAAIALADAGL--ADHPALVKAADWMLAEQID--RPGDWSVRPGLPSGGWAFEFHNDNYPDIDDTAEVVLALRRVDHP-
----EPERIEAAVRRAMRWTLGMQSKNGAWGAFDADNTSPL---PNPFCDFGEV-VDPPSADVTAHVVEMLAHEG-------RT-YDARTRRGIAWLLSE
QEPSGAWFGRWGTNYVYGTGSVVPALIAAGVPAS-HPAVRRAVRWLESVQN-DGGWGEDQRSYLDWMGRG--ASTASQTAWALLALLAAGE--DG-AAVA
RGVTWLAETQRADGSWDEPYFTGGFPWDFSINYHLYRQVFPVTALGRYVHGEPTG--
>tr|G8X0S0|G8X0S0_STREN Squalene-hopene cyclase OS=Streptomyces cattleya (strain ATCC 35852 / DSM 46488 / JCM 4925 / NBRC 14057 / NRRL 8057) GN=SCATT_4
---------------------------------------------------------------------------------------------AARTAER
ATASLLASQHPDGWWKGDLETNVTMDAEDLMLRQFLGIQDE-K--T-LTAAARWIRSQQREDGTWATFYGGPGEISTTVEAYVALRLAGDEPDAP---HM
AAASAWVRKEGGIAASRVFTRIWLALFGWWRWEDLPELPPEVIYLPKWAPLNIYSFGQWARQTIVPLTVVGAHRPVRPA-PF-----DELHTDPAVNPPR
----------P----GVF--QRLDKAL-HA----YRKV-LRPLRRSALNTCARWIIERENDGCWGGIQPPAVVIALHLLYDLDH--PVMRAGLKSLDRFA
VWYE-SRMIEAC-QSPVWDTCLATIALADAGL--PDHPALVKAADWMLDEQVV--RRGDWSVRPELPAGGWAFEFENDNYPDTDDTAEVVLALKRVDHP-
----DRARMRTAIDRAVRWNLGMQSKNGAWGAFDVDNTSPF---PNPFCDFGEV-IDPPSADVTAHVVEMLAAVG-------MA-DDPRTLRGIEWLLTE
QETNGSWFGRWGTNYVYGTGSVVPALVTAGLPVS-HPAIRRAVAWLESVQN-DGGWGEDQRSYPDWAGRG--ASTASQTAWALMALLAAGE--DG-RAVE
RGIRWLAETQKEDGSWDEPYFTGGFPWDFSINYHLYRMVFPVTALGRYLNGEALA--
>tr|D7BYZ8|D7BYZ8_STRBB Squalene-hopene cyclase OS=Streptomyces bingchenggensis (strain BCW-1) GN=hopA PE=4 SV=1
---------------------------------------------------------------------------------------------AREATAR
ATRHLLDRQDEQGWWKGDLETNVTMDAEDLLLRQFLSIQDP-A--T-FEAAARYLRSEQREDGTWATFHGGPPELSATIEAYVGLRLAGDRPDAP---HM
AAASAWVRDHGGIAKSRVFTRIWLALFGWWKWEDLPELPPEIIYFPKWLPLNIYDFGCWARQTIVPLTVVSAKRPVRPA-PF-----DELHTDPRRNPPS
----------A----GAF--QRLDRAL-HA----YHKV-VRPLRRAALRSCARWIVERENDGCWGGIQPPAVLIALHLLYDLDH--PVMRAGLDSLDRFA
VWRE-SRMIEAC-QSPVWDTCLATIALVDAGL--ADHPALIKAADWMLDEQVT--RPGDWSVRPGLPSGGWAFEFDNDNYPDTDDTAEVILALRRVSHP-
----DPERVEAAVRLGTRWTLGMQSSDGAWGAFDVDNTSRL---PNPFCDFGEV-IDPPSADVTAHVVEMLAHEG-------RA-QDPAARRGVAWLLAE
QEADGSWFGRWGTNYVYGTGSVVPALVAAGVPGS-HPAIRRAIRWLEQVQN-DGGWGEDQRSYPDWAGRG--ASAASQTAWALLALLAAGE--ES-KAVE
RGVTWLAETQGDDGSWDEPYFTGGFPWDFSINYHLYRQVFPVTALGRYVNGEPAV--
>tr|A0A0B5F6G4|A0A0B5F6G4_9ACTO Squalene-hopene cyclase OS=Streptomyces albus GN=SLNWT_6814 PE=4 SV=1
---------------------------------------------------------------------------------------------AAEAVRR
ATDFLLARQDAEGWWKGDLETNVTMDAEDLMLRQFLGIRDE-K--T-TQAAALFIRGEQREDGTWATFYGGPGELSTTVEAYVALRLAGDEPEAP---HM
AKAAAWVREQGGIAASRVFTRIWLALFGWWSYDDLPELPPELIYFPQWFPLNIYRFGCWARQTIVPLTVVSAKRPVRPA-PF-----DELHTDPAVVPPQ
----------P----GAF--QRLDKVV-RA----YRKV-PRRVRKAAMRSAARWIVERENDGCWGGIQPPAVVIALHLLYDLDH--PVLRAGLEALDNFA
VWRE-ARMIEAC-QSPVWDTCLATIALADAGL--PDHPQLVKAADWMLGEQVV--RPGDWSLRPQLPPGGWAFEFHNDNYPDTDDTAEVILALRRVKHP-
----DPERVAAAVSRGVRWSLGMQSQNGGWGAFDVDNTSVM---PTPFCDFGEV-IDPPSSDVTAHVVEMLAHEG-------KS-EDPRTRRGVRWLLSE
QEPSGAWFGRWGVNYVYGTGSVVPALVAAGLAPG-HPAIRRAVAWLEKVQN-DGGWGEDLRSYQPWHGVG--ESTASQTAWALLALLAAGE--DS-AATV
RGVEFLARTQAEDGSWDEPYFTGGFPWDFSINYHLYRQVFPLTALGRYLHPEPSA--
>tr|D9WSB0|D9WSB0_9ACTO Squalene-hopene cyclase OS=Streptomyces himastatinicus ATCC 53653 GN=SSOG_01763 PE=4 SV=1
---------------------------------------------------------------------------------------------ARRATDR
AVRHLLSRQDEQGWWKGDLETNVTMDAEDLMLRHFLGIQNP-D--V-LDAAGRYIRSQQAADGTWATFHGGPPELSATVEAYVALRLAGDPPDAP---HM
AAASAWVRNNGGVASSRVFTRIWLALFGWWRWEDLPELPPEIIYFPPWLPLNLYDFGCWARQTIVPLTVVSAKRPVRPA-PF-----DELHADPRRNPPR
----------P----GAF--QRLDRAL-HL----YRKV-LRPLRRAALRSCARWIVERENDGCWGGIQPPAVVIALHLLYDLDH--PVMRAGLESLDRFA
VWRE-SRMIEAC-QSPVWDTCLAVIALADAGL--ADHPALVKSADWMLAEEID--RPGDWSVRPRLAPGGWAFEFDNDNYPDIDDTAEVILALRRVDHP-
----RPERIAAAVRRGVRWTLGMQSRNGAWGAFDVDNTSPL---PNPFCDFGEV-IDPPSADVTAHVVEMLAHEG-------GA-RDPRTRRAVGWLLAE
QEPSGAWFGRWGTNYVYGTGSVVPALVAAGLPAT-HPAIRRAVRWLESVQN-DGGWGEDQRSYPDWIGHG--ASTASQTAWALLALLAAGE--ES-KAVE
RGVGWLAATQDQDGSWDEPYFTGGFPWDFSINYHLYRLVFPLTALGRYVSGEATG--
>tr|E3J5B6|E3J5B6_FRASU Squalene-hopene cyclase OS=Frankia sp. (strain EuI1c) GN=FraEuI1c_2682 PE=4 SV=1
---------------------------------------------------------------------------------------------SDDTLAR
AVAHLKSLQDEAGWWKGDLETNTTMDSEDLMLRHWLGIWNP-E--Q-AERTARFIRSKQYADGSWPIYHAGPGDLNATVESYVALRMVGDSPQDP---HM
RAAAAWARARGGVPATRIFTRIWLALFGWWRWEDLPVLPPELIFVPAKMPLSIYKFASWGRQTIVAIMVLMAHRPAGTP-PF-----AELFPPPATKKAA
AQRKAAALAIGPARPLLF--GGIDRFL-HV----YHRH-IRPVRSLALGLAERWIVVREADGCFGGIQPPTVIMALRVLYPMDH--PVMTAALRSLDEYS
VTLP-ARMQEAC-QSPVWDTCLATIALADAGV--PDDPSLVRAADWMLAEEVRE-RRGDWSVIPDVPTGGWSFEFDNDTYPDVDDSAEVMLALMRVAHP-
----RPEKVVAATYRGLQWVFGMQCADGGWGAFDVDNAGEL---VYPFADFGML-TDPPSADVTAHVVELLGELG-------LG-DDPRTKRGVEWLLHS
QEADGSWYGRWGVNHLYGTGGVVPALRAAGLPAS-HPAIQRAADWLVAKQN-DGGWGESCYSYDETAGVG--VSTASQTAWALLALIAAGR--GTGEAAA
RGVAWLAETQTAEGTWDEDYFTGGFAGYFYINYHLYRLVWPVMALGRYQAALAGK--
>tr|B5H4L1|B5H4L1_STRPR Squalene-hopene cyclase OS=Streptomyces pristinaespiralis ATCC 25486 GN=SSDG_00087 PE=4 SV=2
---------------------------------------------------------------------------------------------AGRAAER
AVEHLLARQDAQGWWKGDLETNVTMDAEDLLLRQFLGIQDA-A--T-VEASARFIRGQQRDDGTWATFYGGPGELSTTIEAYVALRLAGDRPDDP---HM
QRAASWVRSRGGIAAARVFTRIWLALFGWWKHVDLPELPPELILLPKWVPLNIYDFGCWARQTIVPLTVVSAKRPVRPA-PF-----DELHTDPAMNPQK
----------R----GFF--QRADKAL-HL----YHKV-PRRLRRAAMNAAARWIIERENDGCWGGIQPPAVVIALHLLYDLEH--PVMRAGLESLDRFA
VHREPVRMIEAC-QSPVWDTCLATIALADAGL--PDHPALVKAADWMLSEQIV--RPGDWAVRPGLGPGGWAFEFHNDNYPDIDDTAEVILALRRVKHP-
----DPERVEAAVARGTRWNLGMQSLNGAWGAFDADNTSPF---PNPFCDFGEV-IDPPSADVTAHVVEMLAHEG-------MA-EDPRTRRGVRWLLRE
QEANGAWFGRWGVNYVYGTGAVVPALIAAGLPAS-HPSVRRAVTWLESVQN-DGGWGEDLRSYRESIGRG--ASTASQTGWALLALLSAGE--DG-RAVE
RGVAWLARTQRPDGSWDEPYFTGGFPWDFSINYHLYRQVFPLTALGRFLHGEKPV--
>tr|A5EBP6|A5EBP6_BRASB Squalene-hopene cyclase OS=Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182) GN=shc PE=4 SV=1
---------------------------------------------------------------------------------------------LQSTVRA
AADWLIANQKPDGHWVGRAESNACMEAQWCLALWFMGLEDHP----LRKRLGQSLLDSQRPDGAWQVYFGPNGDINATVEAYAALRSLGFRDDEP---AV
RRAREWIEAKGGLRNIRVFTRYWLALIGEWPWEKTPNIPPEVIWFPLWFPFSIYNFAQWARATLMPIAVLSARRPSRPL-PPN---RDALFPHGR-KA--
-----------FDYERFF--RGADKVL-HK----LQNLGLGLFRPAATSRVLEWMIRHDFDGAWGGIQPPWILMALYAEYPLNH--PVLAKGLDALNDPG
WRVDDATYIQAT-NSPVWDTILTLLAFDDAGVLGDYPEAVDKAVDWVLQRQVR--VPGDWSMLPHVKPGGWAFEYANNYYPDTDDTAVALIALAPLRHDP
K--WKAKGIDEAIQLGVDWLIGMQSQGGGWGAFDKDNNQKI---LTPFCDYGEA-LDPPSVDVTAHIIEAFGKLG-------ISRNHPSMVQALDYIRRE
QEPSGPWFGRWGVNYVYGTGAVLPALAAIGED--TQPYIGRACDWLVAHQQADGGWGESCASYMDAVGRG--TTTASQTAWALMALLAANRPQD-KDAIE
RGCMWLVERQ-SAGTWDEPEFTGGFPGAFMLRYGMYRHYFPLMALGRALRPQSHS--
>tr|R7L3C7|R7L3C7_9BACT Squalene-hopene cyclase OS=Coraliomargarita sp. CAG:312 GN=BN601_00762 PE=4 SV=1
---------------------------------------------------------------------------------------------LRETIRS
AIDWLKVRQENDGMWCGPLETNCCMEAQWILAMYFIGFD-DP----KKPKVLQYILDRQREDGAWDVYYDEHGDINTTLECYFALRISGFDPDDP---VL
VKARKWLIENKWVERIRVFTKYWLALFGQWPWAHTPVLPPEIMFLPKWCPFNIYDFAAWARATMMPIAILTARRPIKEL-PEL---QDELFPEGR-DK--
-----------ADYRNFF--MKLDHML-HA----YNRSPIKPFRESAIKLILQWLLEHDEDGAWGGIQPPWIIIVMHIEFAMDQ--INMSRAIDAFNLHW
Q-VKDGIMLQAS-ESPIWDTFLSMTALMDAGETPGTCPELLKALDYVLAKENR--YHGDWSVLGHVEPGGWAFQRANNYYPDIDDAAIAICTLKRIQKLL
PRTTRARRVDSAIRRTINWILAMQSSNGGWAAFDKDNTREL---VTPFCDFGEV-LDPPSADVTAHVVESLALCG-------FSRNHPAIEKALKYLYSE
QEDDGSWFGRWGVNYIYGTGAVLPALMALGDT--ETPAVRKALEWLASKQNADGGWGESVASYMEYSGTGI-PSTASQTAWAMMAIMSVGDKNY-DDTVR
KGCEFLIATQ-KDGSWDEPYYTGGFPGGFMLNYNWYRHYFPLTALGRAEKFFAK---
>tr|A0A0D6PTG8|A0A0D6PTG8_9PROT Squalene--hopene cyclase OS=Gluconobacter frateurii M-2 GN=Gbfr_042_034 PE=4 SV=1
---------------------------------------------------------------------------------------------LAHTVSS
ACDWLIGQQKGDGHWVGSVESNASMEAEWCLALWFLGLEDHP----LRPRLGNALLEMQREDGSWGIYFGGNGDINATVEAYAALRSLGYSEDYP---AL
RKASTWIAEKGGLKNIRVFTRYWLALIGEWPWEKTPNLPPEIIWFPNNFVFSIYNFAQWARATLAPLAILSARRPSRPL-RPD---RDALFPEGR-ER--
-----------FDYTSFF--RTTDKGL-HW----LQSKFRNTVREAAVRHLLEWIIRHDADGGWGGIQPPWVLMALHGEYQFHH--PVMAKALAALDDPG
WRYDEASWIQAT-NSPVWDTMLALMALYDANAQERFTPEMDKGLGWLLDRQVR--VKGDWSILPDVEPGGWSFEYANDRYPDTDDTAVALIALSFCRHRE
E--WKRKGVDEAIARAVNWLIAMQSSCGGWGAFDKDNNKSL---LSPFCDFGEA-LDPPSVDVTAHILEAFGLLG-------LSRELPAVQRALAYVRAE
QDPQGPWFGRWGVNYLYGTGAVLPALAAIGED--SQPYIGKACDWLISCQQDDGGWGESCASYMDSIGRG--TTTPSQTAWALMGLIAAARPQD-YEAIA
KGCRYLIDRQQADGSWTEEEFTGGFPGAFMLRYDLYRQFFPIMALARASRLPDTG--
>tr|Q5NM88|Q5NM88_ZYMMO Squalene-hopene cyclase OS=Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) GN=ZMO1548 PE=4 SV=1
---------------------------------------------------------------------------------------------LNNTLVS
ACDWLIGQQKPDGHWVGAVESNASMEAEWCLALWFLGLEDHP----LRPRLGNALLEMQREDGSWGVYFGGNGDINATVEAYAALRSLGYSADNP---VL
KKAAAWIAEKGGLKNIRVFTRYWLALIGEWPWEKTPNLPPEIIWFPDNFVFSIYNFAQWARATMVPIAILSARRPSRPL-RPD---RDELFPEGR-AR--
-----------FDYEQFF--RTTDRGL-HW----VQSNLRNSLREAAIRHVLEWIIRHDADGGWGGIQPPWVLMALHGEYQLYH--PVMAKALSALDDPG
WRHDESSWIQAT-NSPVWDTMLALMALKDAKAEDRFTPEMDKAADWLLARQVK--VKGDWSILPDVEPGGWAFEYANDRYPDTDDTAVALIALSSYRDKE
E--WQKKGVEDAITRGVNWLIAMQSECGGWGAFDKDNNRSI---LSPFCDFGES-IDPPSVDVTAHVLEAFGTLG-------LSRDMPVIQKAIDYVRSE
QEAEGAWFGRWGVNYIYGTGAVLPALAAIGED--TQPYITKACDWLVAHQQEDGGWGESCSSYMESIGKG--PTTPSQTAWALMGLIAANRPED-YEAIA
KGCHYLIDRQEQDGSWKEEEFTGGFPGAFMLRYDFYRQFFPIMALSRAERLIDLN--
>tr|F1YRB8|F1YRB8_9PROT Squalene--hopene cyclase OS=Acetobacter pomorum DM001 GN=shc PE=4 SV=1
---------------------------------------------------------------------------------------------LTHTLSS
ACEWLMKQQKPDGHWVGSVGSNASMEAEWCLALWFLGLEDHP----LRPRLGKALLEMQRPDGSWGTYYGGSGDINATVEAYAALRSLGYAEDDP---TV
SKAAAWIISKGGLKNVRVFTRYWLALIGEWPWEKTPNLPPEIIWFPNNFVFSIYNFAQWARATMMPLAILSARRPSRPL-RPD---RDALFPGGR-EN--
-----------FDYEDFF--RMADKGL-HW----LQTSFRAPSREAAIKDVLEWIIWHDADGGWGGIQPPWVLMALHGEYQFHH--PVMAKALDALNDPG
WRHDDASWIQAT-NSPVWDTMLSLMALHDANAEERFTPEMDKALDWLLSRQVR--VKGDWSVLPNTEPGGWAFEYANDRYPDTDDTAVALIALASCRNRP
E--WKAKGVEEAIGRGVRWLVAMQSSCGGWGAFDKDNNKGI---LAPFCDFGEA-LDPPSVDVTAHVLEAFGLLG-------LPRDLPCIQRGLAYIRKE
QDPTGPWFGRWGVNYLYGTGAVLPALAALGED--TQPYISKACDWLINSQQENGGWGESCASYMESIGRG--TTTPSQTAWALMGLIAANRPQD-YDAIA
KGCRYLIDLQEEDGSWNEKEFTGGFPGAFMLRYDLYRQLFPIIALSRASRLIKIG--
>tr|A0A0D6P001|A0A0D6P001_9PROT Squalene--hopene cyclase OS=Acetobacter syzygii 9H-2 GN=Absy_022_060 PE=4 SV=1
---------------------------------------------------------------------------------------------LAHTVAA
ACDWLIGEQKADGHWVGPVASNASMEAEWCLALWYLGLEDHP----LRPRLGNALLEMQREDGSWGTYWGGNGDINATVEAYAALRSLGYPEDTP---AL
SKACAWIMRMGGLRNVRVFTRYWLALIGEWPWEQTPNLPPEVIWFPNKFVFSIYNFAQWARATLVPLAILSARRPSRPL-RPD---RDALFPGGR-EN--
-----------FDYVSFF--RTTDRGL-HW----LQTRFRNTVREAAIRHMLEWIIRHDADGGWGGIQPPWVLMALHGEYQFHH--PVMAKALAALDDPG
WRQDDASWVQAT-NSPVWDTMLAIMALHDAKAEERYTPQMNKALDWLLARQVR--VKGDWSILPEVEPGGWAFEYANDRYPDTDDTAVALIALSSCRHRE
E--WKQKGVEAAILRGVNWLIAMQSTCGGWGAFDKDNNRSL---LSPFCDFGEA-LDPPSVDVTAHVLEAFGLLG-------LSPQTPAIQRGLAYIRAE
QEASGAWFGRWGVNYLYGTGAVLPALAAIGED--TQPYITRACDWLVAHQQEDGGWGESCASYMDSIGRG--TTTPSQTAWALMGLIAVNRKQD-HEAIA
RGCRYLIDRQESDGSWTELEFTGGFPGAFMLRYDLYRQFFPLMALSRAARIISFE--
>tr|E8WAC1|E8WAC1_STRFA Squalene/oxidosqualene cyclase OS=Streptomyces pratensis (strain ATCC 33331 / IAF-45CD) GN=Sfla_0644 PE=4 SV=1
---------------------------------------------------------------------------------------------ARHAAER
SVEHLLGRQDEQGWWKGDLATNVTMDAEDLLLRQFLGIQDP-E--T-VKAAARFIRGEQLGDGTWNTFYEGPPDLSATVEAYVALRLAGDRPDDP---HM
IRAAGWVREQGGIAESRVFTRIWLALFGWWKWDDLPELPPELMFFPKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPA-PF-----DELHTDPACNPSR
----------P----GVF--QRLDKAL-HL----YHKV-PRRLRRIAMNEAARWIIERENDGCWGGIQPPAVVIALHLLYDLDH--PVMRAGLESLDRFA
VWRE-ARMIEAC-QSPVWDTCLATIALADAGV--SDHPALVRAADWMLGEEIV--RPGDWAVKPGLAPGGWAFEFHNVNYPDIDDTAEVALALRRVRHP-
----DPARVDAAIERGVRWNLGMQSRNGAWGAFDADNTSPF---PNPFCDFGEV-IDPPSADVTGHVVEMLAVEG-------RA-HDPRTRRGVEWLLAE
QEASGAWFGRWGVNYIYGTGSVVPALIAAGLPAA-HPSVRRAVDWLRSVQN-DGGWGEDLRSYREWIGHG--SSTASQTGWALLALLAAGE--ET-RSVE
RGVAWLAATQQADGSWDEPHFTGGFPWDFSINYHLYRQVFPLTALGRYVYGDPFA--
>tr|A0A081EKD9|A0A081EKD9_STRFR Squalene-hopene cyclase OS=Streptomyces fradiae GN=SFRA_11565 PE=4 SV=1
---------------------------------------------------------------------------------------------AERAAAR
AVRNLLGRQHDEGWWKGDLETNVTMDAEDLLLREFLGIGDR-R--T-TEAAARFIRSRQCPDGTWATFHGGPGDLSATIEAYVALRLAGDAPAAP---HM
AAASAWVREHGGIAASRVFTRIWLALFGWWPWEQLPELPPEMIYLPKWFPLNIYDFGCWARQTIVPLTVVSALRPVRPA-PF-----GELHPDPAAR-R-
----------A----RVF--RRLDRLL-HA----YRRV-PPPLRRAALRACARWIVERENDGCWGGIQPPAVVIALHLLYDLDH--PVLRAGLDSLDRFA
VWQDPSRMVEAC-QSPVWDTCLATIALTDAGL--PGHPALVRAADWMLGEQVL--RPGDWSVRPGLPPGGWAFEFHNDNYPDTDDTAEVVLALRRTAHP-
----DPERVDRAVRRAVRWTLGMQSADGAWGAFDADNTSAF---PNPFCDFGEV-IDPPSADVTAHVVEMLAAEG-------LA-GDPRVRRAVAWLLAE
QEPSGAWFGRWGVNHLYGTGSAVPALVAAGVPAE-HPAIRRAVDWLNSVQN-DGGWGEDLRSYPDWIARG--ESTASQTGWALLALLAAGE--DG-KAVE
RGIGWLARTQREDGSWDEPQFTGGFPWDFSINYHLYRLVFPLTALGRYLTAVGRP--
>tr|E2PZ48|E2PZ48_STRC2 Squalene-hopene cyclase OS=Streptomyces clavuligerus (strain ATCC 27064 / DSM 738 / JCM 4710 / NBRC 13307 / NCIMB 12785 / NRRL 
---------------------------------------------------------------------------------------------ARWATTR
SVEHLLGRQHSQGWWKGDLQTNVTMDAEDLLLRQFLGILDA-R--T-AEAAARFIRGEQRSDGAWATFHGGPGDLSTTVEAYVALRLAGDLPGDP---HL
AGASAWVRHHGGIAGTRVFTRIWLALFGWWPWDELPELPPELIFLPSWFPLNIYDFGCWARQTIVPLTVVSAMRPVRAA-PF-----DELHTDPANRPPR
----------P----GLF--QRADRTL-RR----HRRL-PRRLRRAALAAAARWIVERESDGCWGGIQPPAVLIALNLLHDLDH--PVLRSGIASLDRFA
VWRP-SRMVEAC-QSPVWDTALATVALADAGL--PDHPALVRAAEWLLGEEVV--RTGDWAVRPGLAPGGWAFEFHNDTYPDIDDTAEVILALRRVSHP-
----DPARVDAAVARAGRWTLGMQSAEGGWAAFDADNTSPF---PDPFCDFGEV-TDPPSADVTAHVVEMLAYEG-------RA-HHPRARRGIDWLLER
QESCGAWFGRWGTNYLYGTGAVVPALIAAGIPAA-HPAVRRAVHWLVSVQN-DGGWGEDQRSYQEWAGRG--ASTASQTAWALLALLAAGE--DG-GAAE
RGVAYLAGTQRGDGSWDEPHYTGGFPWDFSINYHLYRQVFPLTALGRYLHGEGAA--
>tr|A0A0B2ADT5|A0A0B2ADT5_9ACTO Squalene-hopene cyclase OS=Streptomyces pluripotens GN=LK06_03910 PE=4 SV=1
---------------------------------------------------------------------------------------------AARAARR
ATEFLLSRQDVQGWWKGDLETNVTMDAEDLLLRQFLGIREE-A--T-TQAAAVFIRGEQREDGTWATFFGGPGELSTSIEAYVALRLAGDEPDAP---HM
AKASAWIREHGGIAASRVFTRIWLALFGWWKWEDLPELPPELIYFPSWMPLNIYDFGCWARQTIVPLTVVSAKRPVRPA-PF-----DELHTDPDTNPPK
----------P----GAF--QRLDKML-HQ----LRKV-PRGLRKAAMNSAARWIIERENDGCWGGIQPPAVVIALHLLYDLQH--PVMREGLASLDRFA
VWRE-ARMIEAC-QSPVWDTCLAVIALADAGL--PDHPQLVKAADWMLGEEIV--RPGDWAVRPQLPPGGWAFEFHNDNYPDIDDTAEVALALRRVRHH-
----DPERVDRAIGRAVRWNLGMQSKNGAWGAFDVDNTSSF---PNPFCDFGEV-IDPPSADVTAHVVEMLAAEG-------LA-HDPRTRRGIAWLLAE
QEPNGAWFGRWGVNYLYGTGSVVPALTAAGLPVA-HPAIRKAVAWLESVQN-DGGWGEDLRSYQQWSGRG--VSTASQTAWALMALLAAGE--DS-TAVE
RGIQWLAGTQREDGTWDEPYFTGGFPWDFSINYHLYRQVFPLTALGRYLHGDPFE--
>tr|M3C0T9|M3C0T9_STRMB Squalene-hopene cyclase OS=Streptomyces mobaraensis NBRC 13819 = DSM 40847 GN=H340_25882 PE=4 SV=1
---------------------------------------------------------------------------------------------AERATAR
ATEYLLSRQNEQGWWKGDLETNVTMDAEDLLLREFLGIRDD-R--T-TRAAARWIRSQQRPDGTWATFHGGPGELSATVEAYVALRLAGDAPDEP---HM
AAASAWVRERGGIAASRVFTRIWLALFGWWKWEDLPEMPPEIMFLPKWMPLNIYDFACWARQTIVPLTVVGAHRPVRPA-PF-----DELHTDPRRNPPR
----------P----GFF--QRLDKAL-HA----YRRV-VRPLRRAALNAAARWIVERENDGCWGGIQPPAVVIALSLLYDLDH--PVLRAGLESLDRFA
VWHEPVRMIEAC-QSPVWDTCLATIALADAGL--ADHPALVKAADWMLDEQVL--RPGDWSVRPKLQPGAWAFEFHNDNYPDVDDTAEVVLALLRVRHP-
----DPARVQEAVRRAMRWTVGMRSRNGAWAAFDVDNTSPF---PNPFCDFGEV-IDPPSADVTAHVVEALAVLG-------KQ-HDPRARGGIEWLLAE
QEECGAWFGRWGVNYVYGTGAVVPALVAAGLPGS-HPALRRAVAWLESVQN-DGGWGEDLRSYRDWMGRG--ASTASQTAWALLALLAAGE--DS-PAVE
RGVAWLADTQRPDGSWDEPYFTGGFPWDFSINYHLYRQVFPLTALGRYLHGEPFA--
>tr|S3AUV0|S3AUV0_9ACTO Squalene-hopene cyclase OS=Streptomyces sp. HPH0547 GN=HMPREF1486_04060 PE=4 SV=1
---------------------------------------------------------------------------------------------AERTAAR
AVDHLLARQDEAGWWKGDLDTNVTMDAEDLLLREFLGIRDE-K--T-SAAAARWIRSQQREDGTWATFYGGPGELSTTIEAYVALKLAGDDPEAP---HM
ARAAAWIREQGGIVRSRVFTRIWLALFGWWRWEDLPEMPPEIIWFPKWFPLNIYDFGCWARQTIVPLTIVCAYRPVHPA-PF-----DELHVDPARNPPA
----------A----GAF--QRIDRAL-HA----YRKV-SRRLRRAAVKEASRWIIERENDGCWGGIQPPAVLIALRLLYDLDH--PVLKAGLESLDRFA
VWHD-TRMIEAC-QSPVWDTCLTAIALADAGL--PDHPALVKAADWMLGEQIV--RPGDWSVRPQLTPGGWAFEFHNDNYPDIDDTAEVALALRRIEHP-
----DSERVNRAIARAVRWNLGMQSRDGAWGAFDVDNTSKF---PNPFCDFGEV-IDPPSADVTAHVVEMLAAEG-------KQ-DDPRTRKAIAWLLSE
QESNGSWFGRWGVNYLYGTGSVVPALVAAGLPTS-HPAIRRAVGWLESVQN-DGGWGEDLRSYIDWIANG--TSTASQTGWALMALLAAGE--DS-KAVE
RGVTWLAETQREDGYWDEPYFTGGFPWDFSINYHLYRMVFPLTALGRYLHGDGLA--
>tr|D3D912|D3D912_9ACTO Squalene-hopene cyclase OS=Frankia sp. EUN1f GN=FrEUN1fDRAFT_6284 PE=4 SV=1
---------------------------------------------------------------------------------------------VVDTLAR
GRDHLLSLQADEGWWKGELETNVTMDAEDLMLRQFLGILTP-A--T-AQETGRWIRSQQLADGGWATFYGGPSDISTTIEAYVALRLAGDDPQAP---HM
RSAAEWVRAAGGIAASRVFTRIWLALFGEWSWDDIPVLPAELSFLPPWFPLNIYDFACWARQTVVALTIVGSLRPVRSF-GF-----DELRVPAPK-PV-
---------------GAF--ERLDVVL-HR----YEKR-FQPLRRLALRRAAEWVIAREADGCWGGIQPPMVIMALHLMYPLNH--PVISMAFRALDRFT
IREQMVRRIEAC-QSPVWDTALAVVALSDAGL--PDDPAMVRAGRWLADEEVR--VAGDWAVRPTLAPGGWAFEFDNDFYPDVDDTAEVVIAIHRLLGDG
HGPELARELRAAAERGVDWSVGMRSSNGAWGAFDADNVRTL---VTPFCDFGEV-VDPPSADVTAHMVEMLALLG-------RA-DHPMTQRAVRWLLDN
QEAGGSWFGRWGVNHVYGTGAVVPALISAGVSAS-HPAILAAAHWLVEHQT-DGGWGEDLRSYREWIGRG--EPTASQTAWALLALLAMEP--REWESIE
RGVRWLCDTQRADGTWDEPQFTGGFPWDFSINYHLYRLVFPVTALGRYVSLTGRA--
>tr|A0A0C1U6Q7|A0A0C1U6Q7_9DELT Squalene cyclase OS=Geobacter sp. GSS01 GN=SE37_12495 PE=4 SV=1
---------------------------------------------------------------------------------------------CRQAVKK
AEQYLLALQNPEGYWVFELEADVTIPSEYIMLQRFLGRIPP-E---LGKRLENYLLDRQLPDGGWPLYAE-GANISATVKAYLALKVLGHSPQAP---HM
IRARLMVLSLGGAARCNVFTRILLALFGQIPWHTPPAMPVEIVLLPQWFIFHLSKVSYWSRTVIVPLLLLYAKQPVCRL-RPE----PELFSTPPDLRHL
---------DG----NAF--IILDRLL-KR----FNRH-PSALHRKAIAEAEQWTRSHQGSGGIGAIFPAMAVMALRVLCGEDD--PDYIRGLQAIDDLL
HRTPSSSICQPC-NSPIWDTCLSLSALMEAGM--P-HPAAKQAVEWLLSQQI-L-SPGDWSLAPDLEGGGWAFQFENTLYPDLDDTSKVIMSLLRAGAL-
----ENELYRDRIARGVNWVLGMQSSDGGWAAFDIDNNHHY---LNPFADHGAL-LDPSTSDLTGRCIELLSMVGFD----R---TFPPIARGIGFLRSE
QEENGAWFGRWGVNYIYGTWSVLSGLRQAGEDMQ-QPYIRKAVGWLTSCQNHDGGWGETCYSY--LGK--G-ASTPSQTAWSLLGLMAAGE--H-SLAVR
RGVRYLLDHQNQ-GTWEEKHFTGGFPRVFYLRYHGYRHFFPLWALGVYSRLSSGQ--
>tr|X5MK76|X5MK76_9PROT Candidatus Phaeomarinobacter ectocarpi complete genome OS=Candidatus Phaeomarinobacter ectocarpi GN=BN1012_Phect101 PE=4 SV=2
---------------------------------------------------------------------------------------------REELIKT
QADQLLEMQRDDGHIVFELEADSTIPSEYVLLQHFLD-VDP-A---KEAKIANYLKRIQNEDGSWPLFQD-GGDISATIKSYWALKLTGEDIDAP---HM
AKAREWVLSRGGASKANVFTRIMLALFAQIPWRGVPVIPVEVMLLPKWFPFHMSKIAYWSRTVIAPLLILCSLKAEARN-PTI----HELFVTPPEEKVY
---------NI----DCF--LVLDKVL-RF----CEPA-PKSLRKRAVDKAVDFFTERNGVDGLGAIYPAMAVMAYDLLYPKDD--PNLMIAKESIERLL
ET--EELYCQPC-VSPVWDTCLASHALMEAGFE-AGDKELDGALDWLKDKQILD-VVGDWAVRPDVRPGGWAFQYNNDYYPDVDDTAVVAMAMHRTG---
-----KPEYNESIERAAEWVVGMQSSSGGWGAFEPENEHFY---LNPFADHGAL-LDPPTEDVTARCLSFLAQLDK-----D--RFAKEIALGVKYLKRD
QQDDGSWWGRWGANYIYGTWSVLCALNAVGEDMS-APYVQRSVAWLKARQRADGGWGEDLATYHE-KSEVH-ESTASQTAWAVLGLMAAGE--E-SEEVR
KGIAYLETAKRD-ARWDEKLYTGGFPKVFYLKYHGYAAYFPLWAVARYENLMKSN--
>tr|W6K6A9|W6K6A9_9PROT Shc protein OS=Magnetospira sp. QH-2 GN=shc PE=4 SV=1
---------------------------------------------------------------------------------------------VDRLVGE
AADWLVDLQEADGHLVFELEADATIPAEYILLNHFLG-PND-K---LERKIAVYLRRIQNDEGGWPLFHE-GTDISASVKAYFALKIVGDDPEAP---HM
VKARQLILGMGGAAKSNVFTRIMLAQFEQIPWRGIPFIPIEVILLPEWFPFHMDKVSYWSRTVMMPLLVLYALHAKARH-PRV----RELFVTPPEEKRY
---------NV----EAL--LVADKYA-RR----MSFL-PKSWKRKAIDKAMTFIRERNGENGLGAIFPAMAVMAMDALYQRDH--PDYVVARKSIDNLL
CK--TETYCQPC-VSPVWDTSLAAHALMEAGRD-E---AAHAALDWLQGRQVLH-VNGDWTARPDVRPGGWAFQYWNDYYPDVDDTAVVGMALDRQG---
-----DPKYIENIDRAVEWIVGMQSSNGGWGAFDAENEHYF---LNPFADHGAL-LDPPTEDVTARCLGFLAQVGY-----G--KDHPAVQAALDYLYRE
QLDDGSWFGRWGSNYIYGTWSVLNALNGVGEDMD-SEAVRRAVDWLKSRQQADGGWGESCSSYYD-EAEDS-VPTPSHTSWALLGLMAAGE--N-SEAVR
RGIRWLSQAPRD-GKWHEELYNAGFPRVFYLHYHGYSAYFPLWALARYRNLVSGN--
>tr|Q13J27|Q13J27_BURXL Terpene synthase OS=Burkholderia xenovorans (strain LB400) GN=Bxe_B0012 PE=4 SV=1
---------------------------------------------------------------------------------------------LDTAITR
ATDAILAAQKPDGHWVYELEADATIPAEYVLLVHYLGEPNV-E---LEQKIARYLRRIQLPDGGWPLFTD-GPDVSASVKAYFALKMIGDPADAE---HM
VRAREAILANGGAEAVNVFTRILLALFGVVSWRAVPMMPVEIMLLPMWFPFHLSKVSYWARTVIVPLLVLNAKRPLARN-PRV----DELFRGAPVTGPR
---------DR----RFF--SGVDMLL-RA----VDGL-PKATRERAVRAAVAFVDERNGEDGLGAIFPAMAVMMYDVLYPADH--PNRAIARQSIEKLL
IKD--EAYCQPC-LSPVWDTSLVAHALLETGEA-R--QAAERGLAWLRPLQILD-VRGDWISRPNVRPGGWAFQYNNDYYPDVDDTAVVVMAMHRSAALT
---HS-EVDREAIARAREWVVGMQSSDGGWGAFEPENTQYY---LNPFSDHGAL-LDPPTADVSGRCLSMLAQLGEL----P--QGSEPAQRAFAYMLKE
QEPDGSWYGRWGLNYIYGTWTALCSLNAAGMPHD-DPRMKRAAKWLLSIQNEDGGWGEGGESYKL-GYERA-PSTASQTAWALMGLMAAGE--N-HEAVA
RGVAYLQREQRE-GLWDETRFTAGFPRVFYLRYHGYRKFFPLWALARFRHLKRHG--
>tr|W9H066|W9H066_9PROT Squalene--hopene cyclase OS=Skermanella stibiiresistens SB22 GN=N825_07240 PE=4 SV=1
---------------------------------------------------------------------------------------------LDEAVSA
AEAAFDRLQRPDGHWIFPLEADATIPAEHILLQHFLD-IDP-E---TQAGLATFIRRRQGADGGWPLFHG-GLDVSCSVKAYFALKAAGDAPDEP---HM
RRARDAILAHGGAARCNVFTRIMLALFGQIPWRGVPVMPVEILNLPTWSPVHISRISYWSRTVVVPLLVVMAHKPRARN-PRV----AELFTVPADVADW
---------HS----RLF--RGLDSFL-QL----IEPR-PKSGRRTAIERAVTFVTERNGEDGLGAIFPAMVIMMYDCLYPADH--PDVVTARGAMDKLL
R---DEILCQPC-LSPVWDTSLACHALAECGGP-HARAMASRAAEWLAERQVLD-VQGDWTWRPGIRPGGWPFQYANPHYPDTDDTAVVVMALDRCG---
-----AERYAERIERGREWIEGLQSTNGGWGAFDADNNSHY---LNPFADHGAL-LDPPTVDVTARCIGMLAQLGL-----D--GKHPTVATGVEFLRRE
QEPNGSWFGRWGTNYIYGTWSALCGLNAVGIAAD-DPMIRRAAYWLLSRQNEDGGWGEGGVSYWPRAEDHC-PSTASQTAWALLGLMSAGL--L-HPAVT
RGVRFLIDNRNA-GLWDEEDFTAGFPRVFYLRYHGYSAIFPLWALARYRGMAEER--
>sp|P33990|SQHC_ZYMMO Squalene--hopene cyclase OS=Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) GN=shc PE=3 SV=2
---------------------------------------------------------------------------------------------VEPIIQK
ATRALLEKQHQDGHWVFELEADATIPAEYILLKHYLGEQDL-E---IEAKIGRYLRRIQG-HGGWSLFYG-GLDLSATVKAYFALKMIGDSPDAP---HM
LRARNEILARGGAMRANVFTRIQLALFGAMSWEHVPQMPVELMLMPEWFPVHINKMAYWARTVLVPLLVLQALKPVARN-RRI----DELFVPDVLPTLQ
----------E----RFF--SALDKVL-HK----VEPY-PKNMRAKAIHSCVHFVTERNGEDGLGAIYPAIAVMMYDALYPENH--PERAIARRAVEKLM
LDGTKEVYCQPC-LSPIWDTALVAHAMLEVGGD-E--KSAISALSWLKPQQILD-VKGDWAWRPDLRPGGWAFQYRNDYYPDVDDTAVVTMAMDRAAKLS
---DLRDDFEESKARAMEWTIGMQSDNGGWGAFDANNSYTY---LNPFADHGAL-LDPPTVDVSARCVSMMAQAGIS----I--T-DPKMKAAVDYLLKE
QEEDGSWFGRWGVNYIYGTWSALCALNVAALPHD-HLAIQKAVAWLKTIQNEDGGWGENCDSYAL-GYEPM-DSTASQTAWALLGLMAVGE--N-SEAVT
KGINWLAQNQDE-GLWKEDYYSGGFPRVFYLRYHGYSKYFPLWALARYRNLKKAN--
>tr|A0A0D2VWC6|A0A0D2VWC6_9PROT Skermanella aerolata KACC 11604 strain 5416T-32 contig17, whole genome shotgun sequence OS=Skermanella aerolata KACC 11604 GN=N
---------------------------------------------------------------------------------------------LNEAVES
AARALIQLQHSDGHWIFPLEADATIPAEHILLQHFLD-IDP-E---VESGLAAFIRSHQGEDGGWPLFHG-GLDLSCTVKAYFALKAAGDPVDAP---HM
KRAREAVLAHGGAARCNVFTRILLALFGQIPWRGVPVMPVEILNLPAWSPVHISRISYWSRTVVVPLLVVMAHKPQARN-PRI----SELFTVPADVVDW
---------HS----RLF--RGIDSFL-SL----IEPR-PKSGRRAAIDRAVKFVTERNGEDGLGAIFPAMAIMMYDCLYPADH--PDAVTARRAMDKLL
PM--GEIMCQPC-LSPVWDTALACHAVAEVGTP-EARQSALAGSAWLVERQVLD-EPGDWSWRPNVRPGGWPFQYANPHYPDTDDTAVVVMALDRCG---
-----AEEFAEPIERGREWIEGLQSSNGGWGAFDADNCAHY---LNPFADHGAL-LDPPTVDVTARCIGMLAQLGF-----K--ADHKSVASGLEFLRRE
QEPNGSWFGRWGTNYIYGTWSALCGLNAVGIRPE-NPMVRRAVDWLLSRQNPDGGWGEGGVSYWPRADDRC-ASTPSQTAWALLGLMAAGE--A-NPATA
RGVRFLIENRNA-GLWDEEDFTAGFPRVFYLRYHGYPAIFPLWAIARYRTMMEEG--
>tr|Q2RYC8|Q2RYC8_RHORT Terpene synthase, squalene cyclase OS=Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIB 8255 / S
---------------------------------------------------------------------------------------------LDDVIGE
SCRWLGERQNQDGHWVFELEADATIPAEYILLNHFLD-IDD-A---REARIASYLRAIQGKHGGWPLFHD-GFDMSATVKAYYALKLTGDGVDEP---HM
VRARQAILEHGGAERTNVFTRFTLAMFDQVPWRACPVTPVEALLLPRFAPFHWSKVSYWSRTVMTPLMILYSRRARAVN-PRI----RELFRRDPEIRDW
---------LK----DAL--IQIDKVL-RV----IEPA-HWAFRDRAEKWALDFIEERNGRDGLGGIYPAIALMAYHTLYAKDH--PGYRIAREAVDGLC
PH--KGEYVQPC-LSPVWDTCLASHAIQEAGQS-AGDRAVDQSNAWLRERQVLD-VVGDWKSRGHLRPGGWAFQYNNPHYPDVDDTAVVVMALARSK---
-----EDEAREAIARAEEWIIGMQSSNGGWGAFDAENEHDF---LNPFADHGAL-LDPPTVDVSARCLGMLAQLGR-----P--KTDPVVARGLDYLWRE
QEADGSWFGRWGTNYIYGTWSALNAFNAVEWDMT-DPRICKAVDWLKSRQRDDGGWGEDCATYWK-RSVSK-ASTPSQTAWAVLGLMAAGE--D-SPEVE
RGIRYLLEAPRD-GKWEEELYNAGFPRIFYLRYHGYSAYFPLWALARYRNLTSGN--
>tr|A0A060A0Z7|A0A060A0Z7_9GAMM Squalene--hopene cyclase OS=Acidithiobacillus caldus ATCC 51756 GN=Acaty_c2080 PE=4 SV=1
---------------------------------------------------------------------------------------------LQRSIAA
AQAALLQHQAADGHWCFEFEADCTIPAEYILMMHYMD-RDA-A---LEAKMAAYLRRKQENHGGWSLYHG-GFDMSASVKAYFALKLAGDDPEAA---HM
RRARSAILAHGGAERANVFTRITLALFGQVPWRAVPFIPVEILLFPRWFPMHIYKVASWSRTVMVPLFILCSLKPQAKN-PLV----RELFTRPPEIDDY
---------FA----RIF--LWFDRLG-RA----LESW-PQALRRRAIARAEAWFIERNGEDGLNGIFPAMVHEALALLYAAEH--PYRQQTRAALTKLV
ERAGE-AYCQPC-VSPVWDTCLALHALLEADG--D-SEAARRSMQWLLDRQITD-APGDWRERPHLAGGGWAFQYANPYYPDLDDTAAVAWALARA--R-
-----RPEDRPAVERAANWLAGMQSRNGGFGAYDVDNTYYY---LNPFADHKAL-LDPPTADVSGRVLAFLAILDRE----Q---DAPVRARLIQYLLRE
QEPSGAWFGRWGTNYIYGTWSVLMGMAELRDPGAVRDAMARAAHWLRSVQQDDGGWGESNDSY--LGL-GQ-ESTAAQTAWACLALMAAGD--D-SESLR
RGIQWLQRHQEQ-GDWQDPYFNAGFPRVFYLTYHGYKIYFPLWALARYRNITERH--
>tr|B7J4Y2|B7J4Y2_ACIF2 Squalene-hopene cyclase OS=Acidithiobacillus ferrooxidans (strain ATCC 23270 / DSM 14882 / CIP 104768 / NCIMB 8455) GN=shc PE=4
---------------------------------------------------------------------------------------------LDRVIAQ
ARQALGGRQAEDGHWCFEFEADCTIPAEYILMQHYMD-RDE-A---LEARIAVYLRGKQADHGGWPLYYG-GFDLSASVKVYYALKLAGDDPELP---HM
RRAREAILAHGGAERSNVFTRITLALFAQVPWRAVPFIPVEIMLLPRWFPFHIYKVASWSRTVMVPLFILCSLKARAKN-PLV----RELFRRPPDITDY
---------FS----YIF--LSLDRFW-RL----MEGW-PHGIRRRALKKAEAWFTARNGEDGLNGIFPAMVHEALELLYPPDH--DYRRQTGAALRKLV
ERAND-AYCQPC-VSPVWDTCLALHALLEEDG--E-SPAVQNGIRWLKNRQIGA-EPGDWRERPHLAGGGWAFQYANPYYPDLDDTAAVGWALARA--G-
-----RAEDRDSIEKAANWLAGMQSRNGGFGAYDVDNTHYY---LNPFADHKAL-LDPPTADVTGRVVAFLAHLARP----R---DRDVLRRAVAYLLRE
QESSGAWFGRWGTNYIYGTWSVLMALAELNDPSL-KPTMERAAYWLRAVQQGDGGWGESNDSY--LGM-GQ-TSTAAQTAWACLGLMAAGD--D-SVALH
RGIAWLQAHQEG-GCWQAPFFNAGFPKVFYLIYHGYAFYFPLWALARYRNLGCMA--
>tr|A0A060URZ1|A0A060URZ1_9GAMM Squalene--hopene cyclase OS=Acidithiobacillus ferrivorans GN=shc PE=4 SV=1
---------------------------------------------------------------------------------------------LDRVIAE
ARTALSSLQAEDGHWCFEFEADCTISAEYILMQHYMD-RDG-P---LEAKIAIYLRNKQADHGGWPLYYG-GFDLSASVKAYYALKLAGDNPDLP---HM
RRAREAILAHGGAEHANVFTRITLALFAQVPWRAVPFIPVEIMLLPRWFPFNIYKVASWSRTVMVPLFILCSLKARAKN-PLV----HELFRRPPEIADY
---------FS----HLF--LSLDRFW-RL----MEDW-PQRIRCRAVQKAEMWFIARNGEDGLNGIFPAMVHEALELLYASDH--VYRQQTRAALRKLV
ERASD-AYCQPC-VSPVWDTCLALHALLEQDG--E-SPAVQSGIQWLKDRQIGA-EPGDWQERPNLAGGGWAFQYANPYYPDLDDTAAVGWALARA--G-
-----RAEDRDSIERAANWLAGMQSSNGGFAAYDVDNTHYY---LNPFADHKAL-LDPPTADVTGRVVAFLAHLARP----R---DRDILRRAVAYLLRE
QESSGAWFGRWGTNYIYGTWSVLMALAELDDPSL-QPAMERAAYWLRAVQQSDGGWGENNDSY--LGM-GQ-ASTAAQTAWACLGLMAAGD--D-SLALH
RGMAWLQMHQEE-GRWPDLFFNAGFPKVFYLIYHGYSLYFPLWALARYRNLGCIA--
>tr|A0A0A1H334|A0A0A1H334_9BURK Squalene-hopene cyclase OS=Burkholderiales bacterium GJ-E10 GN=E1O_05330 PE=4 SV=1
---------------------------------------------------------------------------------------------LDAAIAR
ARSALTERQRPDGHWCFEFEADCTIPSEYILMMHYMD-IDG-A---LQKKLARYIREHQNADGGWPLYWG-GTDLSCAVKAYYALKLAGDDPEAP---HM
QRARQAIIERGGAERANVFTRITLAYFGQVPWRAIPFIPVEVMLLPRWFFFHIYKVSSWARTVMVPLFVLCSLRARAAN-PTL----RELFRRDPDVRDY
---------MK----RAF--LLLDSLG-RL----CEPL-PAALRRRAVRAAEEWFTARNGEDGINGIFPAMAYQALALLYAPDH--PVRVQARRALRLLV
EREDD-AYCQPC-VSPTWDTALALHALCES-G--V-TPEMHRSVDWLLERQTRD-EPGDWRVHPGVPGGGWAFQYHNHFYPDLDDTAAVAWAIARV--I-
-----EPQRPASLDRAADWLVAMQSKNDGFAAYDADNTHYY---LNPFADHKAL-LDPPTADVTARVVAFLSYLGRP----Q---DRPAIARAVGYLLRE
QEPNGSWFGRWGTNYVYGTWSVLVALELLGDERP-REAMARAARWLVSVQQDDGGWGESNDTY--LGR-GQ-PSTVMHTAWACLALMAAGE--H-RASLD
RGIAWLVEHQDA-GRWRDPYFNAGFPRVFYLTYHGYRWYFPLWALARYRRLTGL---
>tr|M5DLZ3|M5DLZ3_9PROT Squalene--hopene cyclase OS=Nitrosospira sp. APG3 GN=EBAPG3_30560 PE=4 SV=1
---------------------------------------------------------------------------------------------LKDGLTA
AREAMLSLQKEDGHWCFPLEADCTIPAEYVLMMHFMD-VDR-D---LEVRLARFIREKQDVHGGWPLYYG-GFDQSCSVKAYYALKLVGDSPDAP---HM
IRARAAILEHGGAARANVFTRIMLAMYGQIPWRGVPFVPVEIILLPRWFPFHLSKIAYWSRTVTIPLSILCSLKAQAAN-PRI----HELFTVDPEERGY
---------FS----RLF--LLIERIA-SP----FEPF-PPFLRRIALKRAEHWIVERNGECGLGAIFPAMVSEALALLYPYEH--PYREQCRRALRGLL
DEGER-VWCQPC-TSPVWDTVLTSLALQEGMG--I-EKPIRKALDWLIPNQILD-APADWQEHPGLSGGGWAFQYANPHYPDLDDTAAVGWALHQA--D-
-----PQAYRESIVRAADWLAGMQSSNGGFAAFDSDNTYYY---LNPFADHGAL-LDPPTSDVTARCTGFLALHGDS----R---HKDAVERGLAYLFRE
QEPSGAWFGRWGSNYIYGTWSVLEAFRLARVDSG-HLAVRRAVQWLKSVQRDDGGWGEGNDSY--KGYF-E-TSTSFQTAWALLGLMAAGE--Q-SHEVS
RGIAYLLHEQDS-GLWHEPWFTAGFPRVFYLKYHGYTSYFPLWALARFQALTRKP--
>tr|D5C0D5|D5C0D5_NITHN Squalene-hopene cyclase OS=Nitrosococcus halophilus (strain Nc4) GN=Nhal_1309 PE=4 SV=1
---------------------------------------------------------------------------------------------LSAAITA
ARDALLKLQHADGHWCFVLEADGTIPAEYILWTHFTG-LEP-E---IERKLAARLRAKQADHGGWPLYEG-GLDISCSVKVYYALKLAGDDPSAP---HM
VRAREAILARGGAAQSNVFTRLALAMFAQIPWRGVPFIPVEIMLLPSWFPFHLNKVSYWSRTVMVPLSILYSLKGQAQN-PRV----QELFVTPPEERHY
---------FP----KVL--LYVERTA-RL----LEPL-PSALRRHAMKKAETWFTARNGEDGLGGIFPAMVHEALILMYGPDH--PLRVQAKKAIQNLL
DEGDS-AYCQPC-LSPVWDTGLASLALQETEG--G-TAPVIRALDWLKERQILE-QPGDWQKHPHLKGGGWAFQYNNSYYPDLDDTAVVAWAMDQA--A-
----APEHYGESIQRACDWLCGMQSRNGGFAAFDSDNTYYY---LNPFADHGAL-LDPPTADVSARCVALLGRLNQP---QY----AQSLKRTLDYLRQE
QESNGSWFGRWGTNYIYGTWSVLTALEQAGFDPQ-ESFIRKAVDWLKQVQRSDGGWGEDNYSY--LGR-YQ-ESTPVHTAWALLALMAAGE--D-SESVK
QGIIYLLQTQQG-GLWDHPAFNAGFPRVFYLKYHGYDKFFPLWALARYRNHLNRQ--
>tr|Q3JBH8|Q3JBH8_NITOC Terpene synthase/Squalene cyclase OS=Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848) GN=Noc_1320 PE=4 SV=1
---------------------------------------------------------------------------------------------ISGAITA
ARDALLKLQQADGHWCFMLEADCTIPAEYILWTHFTG-LEP-E---IERKLAARLRAKQASHGGWPLYEG-GLDISCSVKVYYALKLVGDDPNAP---HM
RRAREAILAQGGGARANVFTRLALAMFSQIPWRGVPFIPVEIMLLPRWFPFHLSKVSYWSRTVMVPLAILYSLKAQAQN-PRV----QELFTVPPEERHY
---------FP----KIL--LSVERTA-RL----LEPL-PSMLRRRALKKAETWFTERNGEDGLGGIFPAMVHESLILLYSPDH--PWRVQAKKALQNLV
EEKNS-ASCQPC-LSPIWDTGLAALALQETEG--G-TAPVIRALDWLKERQILE-QSGDWQVHPNLKGGGWAFQYNNSYYPDLDDTALVAWSMDQA--A-
----TPERYGEAIGRACDWLCGMQSRNGGFAAFESDNTHYY---LNPFADHGAL-LDPPTADVTARCIVLLGRLNKP---QY----AETLQRALDYLRRE
QEPNGSWFGRWGTNYIYGTWSALTALEQANIDPQ-EGFIRKAVEWLKQVQRLDGGWGEDNYSY--LGR-YQ-ESTPVHTAWALLALMAVGE--N-SEAVK
KGIAYLLQIQQE-GLWDHPAFNAGFPRVFYLKYHGYDKFFPLWALARYRNHLNRQ--
>tr|H5SHE8|H5SHE8_9GAMM Squalene-hopene cyclase OS=uncultured gamma proteobacterium GN=HGMM_F29A09C03 PE=4 SV=1
---------------------------------------------------------------------------------------------LDRAIAK
AQSALLQRQHPEGYWVFELEADCTIPAEYILMMHHMD-VDE-I---LQARLANYLRAKQQEDGSWPLYTG-GGNLSCSVKAYYALKLAGDSPSAP---HM
QKAREFILSQGGAAKANVFTRILLAFFQQIPWRGIPFIPVEIMLLPRWFPFHLEKVAYWSRTVMVPLSILYSLKVKAKN-PKV----RELFVTPPEERGY
---------FS----KFV--LALERIG-LK----LEPW-PFRIRQRALEKALAWVTERNGEDGLGGIFPAMVYEAMEALIPPED--PRRQIAKQALKKLL
HRDHE-SYCQPC-LSPVWDTGLSLLALQEVQR--GVAAAIDRALDWLVSKQLRD-QPGDWQARPHLEGGGWAFQFNNSYYPDVDDTAVVAYSLLNS--D-
-----RPEHREAALRAVRWIAGMQSKNGGWGAFDPDNTYYY---LNPFADHGAL-LDPPEADVSARCVMLLSAAGKA---VP--YFREVAKRGLDFLWRQ
QEADGSWFGRWGSNYIYGTWSVLMGLEHYGVPKD-DPRVLRAVAWLKSVQREDGGWGESNDSYEDIGR-FH-TSLACQTAWALLALMAAGE--Q-SEAVQ
RGIDFLLRTQQE-GFWRDEYFNAGFPRVFYLKYYGYDKFFPLWALARYRNETKRL--
>tr|Q0AFY0|Q0AFY0_NITEC Squalene-hopene cyclase OS=Nitrosomonas eutropha (strain C91) GN=Neut_1507 PE=4 SV=1
---------------------------------------------------------------------------------------------LDEAITR
AYTALLAQQREDGHWCFPLEADCTIPAEYILMMHFMD-VDT-V---LERKIANFLRTRQVGHGGWPLYYG-GFDMSCSVKTYYALKLAGDSPEAA---HM
VHARNAILERGGAARSNVFTRLLLAMYRQIPWRGVPFVPAEIMLLPRWFPFHLSKVAYWSRTVMVPLSILCTLKAKAIN-PRV----QELFVVDPVEKNY
---------FP----RLL--LYVERLA-SK----LEPF-PSFIRRRAVKKAEQWVIERNGNDGLGAIFPAMVYEALTLLHDRDH--PLLQQCRQSLRELL
DEGEEITWCQPC-VSPVWDTVLATLALQEDKQ--A-SEPIRRALDWIVPLQILD-EPGDWRDRPNLLGGGWAFQYANPHYPDLDDTAAVAWALIQT--G-
-----AEDYRVSITRAADWLAGMQSSNGGFAAFDIDNAYYY---LNPFADHGAL-LDPPTSDVSARCVGLLALNGEV----R---HQEAVKRGLDFLFNE
QESSGAWFGRWGSNYIYGTWSVLEAFRLARVDKG-HQAVQRAIQWLESVQRADGGWGETNDSY--LGQL-E-ASTSFQTAWAVLGLMAAGE--E-NTAVR
KGIDYLLRTQIA-GLWEEPWFTAGFPRVFYLKYHGYSKYFPLWALNRYRTLSSKS--
>tr|Q82VC6|Q82VC6_NITEU Uncharacterized protein OS=Nitrosomonas europaea (strain ATCC 19718 / NBRC 14298) GN=NE1168 PE=4 SV=1
---------------------------------------------------------------------------------------------LDDAITR
ARSALLAQQREDGHWCFSLEADCTIPAEYILMMHFMD-IDT-A---LERRIANFLRNRQVGHGGWPLYYG-GFDMSCSVKVYYALKLAGDSPEAA---HM
VRARNAILERGGAARSNVFTRLLLAMYRQIPWRGVPFVPAEIMLLPRWFPFHLSKVAYWSRTVMVPLSILCTLKAKAAN-PRI----RELFTVDPEEKNY
---------FP----HLL--LYLERLG-SK----LEPL-PSFIRRRALKKAEQWTIERNGRDGLGAIFPAMVYEALTLLYDHDH--PLLQQCRLALRELL
NEGEDITWCQPC-VSPVWDTVLASLALQEDER--A-NGPVRHALDWLVPLQALD-QPGDWRNRPDLPGGGWAFQYANPHYPDLDDTAAAAWALCQA--D-
-----TEDYRTSITRAADWLAGMQSSNGGFAAFDIDNVHYY---LNPFADHGAL-LDPPSSDVTARCIGLLALNGEA----R---HQETVKRGLTFLFNE
QEPSGAWFGRWGTNYVYGTWSVLEALKLARVDHD-HQAVKRAVQWLKSVQRADGGWGETNDSY--LGQL-E-TSTSFQTAWAVLGLMAAGE--G-STAVR
NGIDYLIRTQSA-GLWEEPWFTAGFPKVFYLKYHGYSKYFPLWALNRYRAMNSRS--
>tr|Q2Y5X6|Q2Y5X6_NITMU Squalene cyclase OS=Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849) GN=Nmul_A2556 PE=4 SV=1
---------------------------------------------------------------------------------------------LKAGLEA
ARGALLAQQREDGHWCFPLEADCTIPAEYILMMHFMD-VDL-D---LEVRIARFIREKQDAHGGWPLYYG-GFDLSCSVKAYYALKIVGDSPDAP---HM
VRARAAILKHGGAARANVFTRLLLAMYDQLPWRGVPFVPVEIILFPKWFPFHTSKVAYWSRTVMVPLSILCSLKARAAN-PRV----RELFTVPPGERNY
---------FP----RVF--LLIERTL-SL----LEPF-PQGVRRLALRRAESWIVERNGDSGLGAIFPAMVGEALALLYPYDH--PAREQCRKALRLLL
EEGER-TWCQPC-VSPVWDTVLTCLAFQEDTE--V-QKPIRKALDWLVPCQVLD-APADWQEHPGLPGGGWAFQYANPHYPDLDDTAAVAWALYQA--D-
-----PKAYQESISRAADWLAGMQSSNGGFAAFDSDNTYYY---LNPFADHGAL-LDPPTSDVSARCAGFLALYGQS----R---HKQALERSLAYLFNE
QEASGAWFGRWGSNYIYGTWSVLEAFRLAGIDAG-HPAIRRAVHWLKSVQREDGGWGESNDSY--QGQF-H-TSTSFHTAWALLALMGAGE--R-SHEVH
RGIAYLLREQDS-GLWHEPWFTAGFPRVFYLKYYGYTKYFPVWALTRFHALNRKF--
>tr|A4BP96|A4BP96_9GAMM Terpene synthase/Squalene cyclase OS=Nitrococcus mobilis Nb-231 GN=NB231_11694 PE=4 SV=1
---------------------------------------------------------------------------------------------IEEAILA
ARAALLAHLHPDGYWCFELEADCTIPAEYIMMMHYTG-LEA-A---LELKLARYIRECQLQEGGWPLYYG-GMDISCSVKAYFALKLAGDDPEAA---HM
RRARKAVLERGGAVNANVFTHIALALFGEIPWRGVPFMPPEILLLPRWFPFHLSKVSYWSRTVMVPLFILAAHKPRARN-PRI----SELFVTDPQETGY
---------FK----RLF--ITLDALG-RR----IEPF-PRAVRAKALRRAAEWFITRNGEHGLGAIFPAMVYEALELLYAADH--PLRQQVRKGLRDLV
EQADR-AYCQPC-LSPIWDTALACLALQEADR--G-SAQVRHALDWLQARQLLD-TPGDWSEHPSLPGGGWPFQFRNDHYPDLDDTAIVAWAMQRA--S-
----DPERYGAAIRRATVWLLGMQSANGGFAAFDSDNTRYY---LNPFADHGAL-LDPPTSDVTARVVALLGSLDGE---VH---DRSALNRAVAFLHRE
QEAEGCWYGRWGTNYIYGTWSVLTALEQLGYDFN-APWVRKAVIWLKSVQRDDGGWGESNDTY--PDRQAD-ESTPFQTAWAVLALIAAGE--R-SPEVW
RGVEYLLRHQRP-GLWYCPWFTAGFPRVFYLKYHGYDAYFPLMALARYRNCVLDN--
>tr|F9ZFJ9|F9ZFJ9_9PROT Squalene/oxidosqualene cyclase OS=Nitrosomonas sp. AL212 GN=NAL212_0906 PE=4 SV=1
---------------------------------------------------------------------------------------------LENKLTQ
ARSAMLSLQKPDGHWCFPLEADCTIPAEYILMMHFMD-IDV-I---LENKIARFIREKQDTHGGWPLYYG-GFDISCTIKSYYALKLVGDSPDAA---HM
VRAREAILERGGAAKANVFTRLLLAMYEQIPWSGVPVVPTELMLLPSWFPFHISKVSYWSRTVMIPLSILCTIKARAIN-PRV----RELFIVPPEEKNY
---------FP----RAF--MLVERVL-SR----VEPK-PQAIRQYSIRKAENWTLERNGECGIGAIFPAMVHESLALLYAYDH--PSRVQCRNALRGLL
DEGER-AWCQPC-TSPVWDTVLTCLALQEDPA--A-QGPVLKALDWLVDQQVLD-EPGDWRDRPDLLGGGWAFQYANPHYPDLDDTAAVAWALDQS--D-
-----AQRYQKPLDRAANWLAGMQSRNGGFAAFDIDNTYHY---LNPFADHGAL-IDPPTSDVTARCVGLLGKYGK---------HQREVWRGISFLLRE
QEKNGSWFGRWGTNYIYGTWSVLEAFQLANFDMQ-HTSVRRAVKWLESVQRVDGGWGETNDSY--LGQFPQ-TSTTFQTAWAVLGLMAAGE--N-SKSVR
RGINYLLHNQAD-HLWEDPWFTAGFPRVFYLRYHGYSKFFPIWALVRYRALTKER--
>tr|F8GDP6|F8GDP6_NITSI Squalene-hopene cyclase OS=Nitrosomonas sp. (strain Is79A3) GN=Nit79A3_1066 PE=4 SV=1
---------------------------------------------------------------------------------------------LENKFTQ
AREAMLSLQKSDGHWCFPLEADCTIPAEYILMMHFMD-VDV-L---LETKIARFIRDKQDSHGGWPLYYG-GFDISCTIKAYYALKLVGDSPDAA---HM
VRAREAILERGGAAKANVFTRLLLAMYDQIPWRGVPVVPAELVLLPRWFPFHLSKVSYWSRTVMVPLSILCTMKASAVN-PRV----RELFIIAPEEKNY
---------FP----RFF--MLTERVL-SR----IEPR-PRSVRQYAIRRAESWTLERNGECGIGAIFPAMVHESLALLYAYDH--PNRVQCRNALRGLL
DEGER-VWCQPC-TSPVWDTVLTSLALQEDPM--T-QKPVLQALDWLVEQQILD-EPGDWRDCPDLPGGGWAFQYANPHYPDLDDTAAVAWAMDQG--D-
-----AERYQKPLERAANWLCGMQSRNGGFAAFNIDNTYHY---LNPFADHGAL-IDPPTSDVTARCVGFLGKYGRS----H---HQHAVLRGISYLLRE
QESNGAWFGRWGTNYIYGTWSVLEAFRLVQFDMQ-HKSVRRAVQWLESMQRADGGWGETNDSY--LGKFPE-TSTAFQTAWAVLGLMAAGE--N-SESVR
RGINYLLRNQSS-HLWEEPWFTAGFPRVFYLRYHGYSKFFPLWALARYRALTRTV--
>tr|T0ZXF7|T0ZXF7_9ZZZZ Squalene-hopene cyclase OS=mine drainage metagenome GN=B1B_11729 PE=4 SV=1
---------------------------------------------------------------------------------------------LRRVIER
ARVALLERQKQDGHWCFELEADCTIPSEYILMMHYLG-IDH-E---LQTKLSQYIRRRQSSHGGWPHFTG-GFDLSSSVKAYYALKLAGDHIQEK---HM
ERARRAILAAGGAACTNVFTRITLYLFRQVPLRAIPFIPVEIVLLPRWFPFHLSKVSYWSRTVMVPLFVLCSLRARAQN-PLI----AELFTVPADETDY
---------FK----KFF--LMLDYIG-RK----LEPW-PPFVRNRALVQACEWICERNGDSGLGAIFPAMVYEALLLLYDPSH--PYCQNARFAIQKLL
VREDE-AYCQPC-VSPIWDTAFAMLALESAGD--T-SPCLRKAADWLKNKQITS-QRGDWAIRPKLPPGGWAFQYANAHYPDLDDTAVVAWILERS--H-
----LRAAYLDAIEKAITWTVGMQSKNGGFASFDVDNTHTY---LNPFADHGAL-LDPPTSDVSAHVLGFLGRLARP----E---LQVTLDRCLAYLRSE
QEANGSWFGRWGTNYIYGTAHVLVALEEAHLDIH-EEWIQRASQWLTSVQRDDGGWGESNDTY--CGQ-GT-SSTAFQTAWALLGLMATGH--Q-SPAAK
RGVQYLLETQRP-GTWSDEDFTAGFPRVFYLNYHGYSLYFPLWALGCYQSRLAEH--
>tr|H8L1C6|H8L1C6_FRAAD Squalene-hopene cyclase OS=Frateuria aurantia (strain ATCC 33424 / DSM 6220 / NBRC 3245 / NCIMB 13370) GN=Fraau_3212 PE=4 SV=1
---------------------------------------------------------------------------------------------LTRAMEQ
ARAALLGRQAADGHWCFELESDATITAEYILMTHFMD-IDD-I---LQAKLARYLRATQQSHGGWPLYHG-GLDLSCTVKAYFALKAAGDSAEAP---HM
RRAREAVLERGGAAKANVFTRMLLAMFGQVPWRATPYTPVELMLFPRWAPIHVDKVAYWARTTMIPLMALCSMQARAAN-PRA----AELFVTPAEERDY
---------FA----RVF--LALDKLG-RA----VDPL-PKAIRRKAIQKAADWCAERNGEDGLGAIFPPMVYEMYHLLYPADH--PLMQTCRKALHKLL
FRPDGSAYCQPC-VSPVWDTAWALMALQHTG---DTQSAVQRGYDWLLPRQVLE-LRGDWKECDQVRPGGWAFQYANDYYPDIDDTAVVAGMLHSRAQRL
---GDPQRYREATDRAAEWMLGLQSKNGGFAAFDADCTRYY---LNPFADHGAL-LDPPTEDVTGRVLACLGLLKRP----Q---DAEVIRRGVEYLRTT
QLQDGSWWGRWGTNYVYGTWSALAGLALVGEDRQ-QPYIRKAIEWLYACQNADGGWGETNDSY--LGQNQG-VSTPNHTAWALLALIAIGE--D-HPAVA
RGIEHLLATQQA-GLWHHPSHNAGFPRVYYLKYHGYTAYFPLWALSQYRRRRSAA--
>tr|T1C353|T1C353_9ZZZZ Squalene-hopene cyclase OS=mine drainage metagenome GN=B1A_10106 PE=4 SV=1
---------------------------------------------------------------------------------------------LHQAIER
ARVALLAQQHADGHWCFELESDCTITAEYILMMHYMD-IDS-V---LQEKMARYLRAIQATHGGWSQYHG-GIDQSCTVKAYYALKAAGDDPAME---HM
RRARDAVLAHGGAAKCNVFTRILLAQFEQVPWRAVPYVPVEIMLLPRWAPFHIEKISYWARTTLVPLTILCSLKAKANN-PNV----RELFVTPPEERHY
---------FI----RGF--LVLDKVG-RA----LDRW-PRRLRKHAIHKAEAWFLPRNGEDGIGAIFPPMIYEAMALLYPKDH--PARQTCLRSIQKLI
HRADGSAYCQPC-VSPVWDTGWCALALMHSN---ETQAVIARACDWLTAKQVLE-HKGDWVAAPDVAPGGWAFQYANPAYPDIDDTALIAALLHVQDRRR
---AESGRHRVNTDRAADWMLALQSKNGGFAAFDADNTHDY---LNPFADHGAL-LDPPTEDVSGRVIACLGVLARE----Q---DRGSIRRCINYLRAS
QQADGAWWGRWGSNYIYGTWSVLSGLALAGEDPQ-QPYICKAIDWLRARQHADGGWGETNDSY--LGTNQN-VSTPHSTAWAMLAQLAVGE--Q-SDSVQ
RGLAFLLANQQA-GVWSHPSHNAGFPRVYYLRYHGYATYFPLLALTCYRRQLRRV--
>tr|H8GLM0|H8GLM0_METAL Squalene-hopene cyclase OS=Methylomicrobium album BG8 GN=Metal_2860 PE=4 SV=1
---------------------------------------------------------------------------------------------LDRAIKK
AQDSLIKLQDPAGFWVFELEADCTIPSEYIMMMHFVD-IDV-G---LQNKIANYLRSRQSEDGSFPLFTG-GGDISGSVKVYYALKMAGDDIDAP---HM
KRLREWILSQGGAAKANVFTRIALATFEQLPWRGVPYIPVEIMLFPKWFPFHLDKVSYWSRTVMVPLFILCSMQAKAKN-PHV----LELFTVHPDEKHY
---------FP----KIF--LGLDKLG-RL----TAPL-PKTMHERAIQKALDWFTERNGEDGLGGIFPAMVYESMLLLMPEDH--PNVVIARQSIDKLL
INEND-AYCQPC-LSPVWDTGLAALALQEANR--N-KASLTKAYDWLKTKQLKD-EPGDWQVKPDLPGGGWAFQFNNPHYPDVDDTAVVAFAMADS--G-
-----LPGMEEPVQRATRWIEGMQSKNGGYGAFDADNTYYY---LNPFADHGAL-LDPPTADVSARCAMLMAKVAEE---RK--EYLPTLERTVEYLRRE
QEADGSWFGRWGTNYVYGTWSVLLGLEQTGLPKD-DPMYTKAASWLKSIQREDGGWGEDNFSY--FGK-YR-FSTAFQTAWAVLGLIAAGE--K-SPEVK
AGIDFLLRKQQA-GFWNDKCFTAGFPRVFYLKYHGYDKFFPLWALARYRNELARP--
>tr|A0A0A6QYC1|A0A0A6QYC1_9GAMM Squalene--hopene cyclase OS=Methylomonas denitrificans GN=JT25_15305 PE=4 SV=1
---------------------------------------------------------------------------------------------LNAAIAR
AQEKLLSLQSPEGYWVFELEADCTIPSEYIMMMHYLD-IDE-E---LQRKIAIYLRSRQAEDGSYPLFTG-GGDISGSVKAYYALKMAGDSVDAP---HM
VKLREWILGQGGAARANVFTRIALAIFEQLPWRGVPYIPVEIMLLPSWFPFHLDKVSYWSRTVMVPLFIMCTLKAKAKN-PHV----LELFVVHPDEKHY
---------FP----KFF--LGLDKLG-RV----TQPL-PQRMREHAIQKAVDWFTERNGEDGLGGIFPAMVYQAMLLLFPADH--PNVVIARQSIDKLL
IKEDY-AYCQPC-LSPVWDTALAALALQESDK--A-AANLTQAYDWLKSVQLSD-EPGDWRVRPDLAGGGWAFQFANPHYPDVDDTAVVGFAMADS--N-
-----LPELDESIHRATRWIVGMQSQNGGYGAFDVDNTYYY---LNPFADHGAL-LDPPTVDVSARCAMLMARVAKD---HD--EYLPALERTIEYIRGD
QEADGSWFGRWGTNYIYGTWSALLGLEQTNVPKT-DPMYTKAAAWLKSVQREDGGWGEDNLSY--FGR-YH-FSTAFQTAWAVLGLIAAGE--H-SQEVK
AGIDFLLRGQQA-GVWNDPCFTAGFPKVFYLKYHGYDKFFPLWALARYRNELAKQ--
>tr|A0A0C4YJL4|A0A0C4YJL4_9BURK Cupriavidus basilensis strain 4G11 chromosome secondary, complete sequence OS=Cupriavidus basilensis GN=RR42_s1630 PE=4 SV=1
---------------------------------------------------------------------------------------------LHRAIDA
ARDALLSHQHRDGHWCFELESDATITAEYILMMHFVD-IDA-G---LQAAMAVYLRSLQRRHGGWDLYHG-GLDVSCSVKAYFALKAAGDDPDAP---HM
AQARRAILAQGGAAKANVFTRILLATFGQVPWRATPFVPVELILFPRWAPVHLDKMAYWARSTLVPLTVLCSLRAKAAN-PHV----SELFVTPPEERHY
---------FS----KAF--LVADKVA-RT----IEPW-PAAVRRRAIARAQAWCVERNGEDGLGGIFPPMVYEMMTLLVPKTD--PARVTCLAAIRKLV
RRADGSAYCQPC-LSPVWDTAWSIMALQHAG---TTQQAVQRAYDWLEARQVRD-LRGDWSKVASVQPGGWAFQYANAYYPDIDDSAVVAAMLAVHARRI
---GQPERYQDAVASAVKWMVGLQSRNGGFGAFDANCDREY---LNPFADHGAL-LDPPTEDVSGRVLLCIGLSGNR---QA---HAAAVERCVAYLRRT
QRADGAWWGRWGSNYIYGTWSVLAGLALVGEDVR-QPYIRKAVDWLLHCQHADGGWGETNDSY--LGTNGG-ESTPNSTAWALLALFAVGE--D-TPAVR
RGIAYLLDCQAG-GLWQHPSHNAGFPRIYYLKYHGYTAYFPLWALTRYRQLAGRT--
>tr|G3IWH8|G3IWH8_9GAMM Squalene-hopene cyclase OS=Methylobacter tundripaludum SV96 GN=Mettu_0710 PE=4 SV=1
---------------------------------------------------------------------------------------------LNRAISK
AQDKLLSLQDKDGYWVFELEADCTIPSEYIMMMHYLG-IDE-S---LQAKIANYLRPRQSEDGSYPLYTG-GGDISCSVKVYYALKMVGDSIDAP---HM
VRLRNYILSQGGAAKANVFTRIALATFEQLPWRGVPYIPVEIMLFPSWFPFHLDKVSYWSRTVMVPLFILCTLKATAKN-PNI----LELFITHPDEKHY
---------FP----KIF--LGLDKLG-RL----TRPL-PKKAHELAIEKAKNWFIERNGEDGLGGIFPAMVYEAMLLLMPKDH--HHVVTARKAIDKLL
INEHD-AYCQPC-LSPVWDTALAALALQEADK--A-SQSLTRAYDWLKSKQLSD-EPGDWRIKPDLAGGGWAFQFENPHYPDVDDTAIVAFAMAES--N-
-----IPNLDESIHRATRWIVGMQSRNGGYGAFDVDNTHYY---LNPFADHGAL-LDPPTSDVSARCAMLMARVAQD---HD--EYQPALERTIDYIRSE
QEQDGSWFGRWGTNYIYGTWSALLGLEQTGLPKT-DPMYTKAATWLKSVQRGDGGWGEDNYSY--HGK-YH-FSTAFQTAWAVLALMAAGE--H-SPEVK
AGIDFILRNQQA-GVWNDECFTAGFPKVFYLKYHGYDKFFPLWALARYRNEFLKK--
>tr|G4T320|G4T320_META2 Squalene-hopene-cyclase OS=Methylomicrobium alcaliphilum (strain DSM 19304 / NCIMB 14124 / VKM B-2133 / 20Z) GN=shc PE=4 SV=1
---------------------------------------------------------------------------------------------LNKTISK
AQDYLLKLQQPDGHWIFELEADCTIPSEYIMMMHYLG-IDE-G---LQAKIANYLRSRQSEDGSYPLFTG-GGDISGSVKVYYALKMAGDSIDAP---HM
QKLRNYILSQGGAARANVFTRIALAMFEQLPWRGVPYIPVEIMLLPKWFPFHLDKVSYWSRTVMVPLFVLCSEKATAKN-PNV----LELFVVHPDEKHY
---------FP----KFF--LMLDKLG-RV----TRPL-PQSMHRKALDRAQDWFIERNGEDGLGGIFPAMVYEAMLLLMPKDH--ELVVTARKAIDKLL
INEHD-AYCQPC-LSPVWDTGLTALALQEVDK--N-RDALIRAYDWLKSKQLID-EPGDWQVKPDLEGGGWAFQYANPHYPDVDDTGLVAFAMADS--N-
-----LPELDESIHRATRWIVGMQSENGGYGAFDVDNTYYY---LNPFADHGAL-LDPPTVDVTARCAMLMARVAKG---HD--EYRPALQRTIDYIRSE
QEADGSWFGRWGTNYIYGTWSVLLGLEQTDVPKT-DPMYVNAARWLKSVQREDGGWGEDNFSY--FGK-YR-FSTAFQTAWAIIGLIAAGE--H-SPEVK
AGVEFLMKTQLT-GSWNDKCFTAGFPRVFYLKYHGYDKFFPLWALAKYRNAINNS--
>tr|G0A747|G0A747_METMM Squalene-hopene cyclase OS=Methylomonas methanica (strain MC09) GN=Metme_3474 PE=4 SV=1
---------------------------------------------------------------------------------------------LNAAIER
AQSKLLSLQNPAGYWVFELEADCTIPSEYIMMMHYLD-IDE-A---LQSKIAAYLRKRQSEDGSYPLFTG-GGDLSCSVKVYYALKMAGDAIHEP---HM
KRLREWILSQGGAARANVFTRIALAIFEQLPWRGVPYVPVEIMLLPSWFPFHLDKVSYWSRTTMVPLFILCTLKAKAKN-PRV----LELFVVHPDERHY
---------FP----KLF--LGLDMLG-RV----TRPL-PKRVTDRAIQKAVDWFTERNGEDGLGGIFPAMVYESMLLLFPKDH--PNVLIARQSINKLL
IKDHE-AYCQPC-LSPVWDTALASMALLEADK--Q-AAHLSNAYDWLKSVQLSD-EPGDWQVCPNLAGGGWAFQFANPHYPDVDDTAIVAFSMAES--G-
-----QTGLNESIHRATRWIVGMQSKNGGYGAFDVDNTYYY---LNPFADHGAL-LDPPTVDVSARCAMLMARVSKD---HA--EYLPALQRTIDYIRND
QEADGSWFGRWGTNYIYGTWSVLLGLEQTSLPKT-DPMYTKAAAWLKSVQREDGGWGEDNLSY--FGR-YH-FSTAFQTAWALLGLIAAGE--H-SPEVK
AGIDFLLRTQQA-GVWNDPCFTAGFPRVFYLKYHGYDKFFPLWALARYRNELAKS--
>tr|L2E8Q3|L2E8Q3_9BURK Squalene-hopene cyclase OS=Cupriavidus sp. HMR-1 GN=D769_27604 PE=4 SV=1
---------------------------------------------------------------------------------------------LDAAIVR
ARDALLDRQHPDGHWCFELECDATITAEYILMMHFVD-IDT-A---LQARMAKYLRAVQRRHGAWDLYFG-GLDISCSVKAYFALKAAGDPPDAP---HM
IRAREAILARGGAAKSNVFTRILLATFGEIPWRGTPFMPVEFVLFPRWAPIHMDKVAYWARTTMVPLLVLCSIRAAAKN-PLV----QELFVTPPEEREY
---------FP----RAF--LIADRVV-RH----LEPL-PRALRRRAIQRAVEWSEARNGEDGFGGIFPPMVYEMMVLLYPEDH--PLRVECKAALKKLV
HRDDGSSYCQPC-LSPVWDTAWSVMALEQAPP--DTEAAIASAYDWLTDRQVLD-LRGDWESAPNTPPGGWAFQYENPYYPDIDDSAVVLAMLHARGKRT
---GQPGRYEMPVARCLDWIIGLQSRNGGFGAFDANCDRDF---LNPFADHGAL-LDPPTEDVSGRVLLALGITERP----Q---DATARERCIQYLRDT
QQPDGSWWGRWGTNYIYGTWSVLAGLGLAGVDRK-LPMVRNGLQWLRGKQNADGGWGETNDSY--LGKHED-GSMAEQTAWAMLGQMAVGE--D-ADSVH
RGAAYLLEAQNE-GFWMHPYHNAGFPRIFHLKYHGYTAYFPLWALGRYRRLAAAR--
>tr|S9TDK7|S9TDK7_PHAFV Putative squalene--hopene cyclase OS=Phaeospirillum fulvum MGU-K5 GN=K678_16665 PE=4 SV=1
---------------------------------------------------------------------------------------------LEDAVRG
SAAALMSSQKEDGHWVFKLEADATIPAEFVLYLHYLD-RDP-P---LEQRIGVYLRDIQDTHGGWSLFHG-GFNISASVKAYFALKAIGDDIDAP---HM
KQAREAILAHGGAATSNVFTRTLLALFGQIPWKGVPVMPVEVMLLPRWFPFHLDRVSYWSRTVIAPLVVLMSLRPQARN-PLI----PELFTIPPEVTNW
---------YL----YVF--RGLDRVL-HR----VQPY-PQGLRRLAIERAVAFVDERNGEDGLGAIFPAMVVLMYDLLVPKDD--PRVVIAKKSIRNLV
EE--DRAWVQPC-LSPVWDTALATHALLEAGGP-EAEDSARRAADWLVDRQITD-VVGDWAVRPGLAPGGWAFQYANPHYPDVDDTAVVMAALDRLD---
-----PERYAESIQKGAVWLRGMQSEDGGWGAFDAENTAHY---LNPFSDHGAL-LDPPTADVSARCVSVLSVLGE-----R--QTDPVAKEGVAYLLKE
QEPNGSWFGRWGTNYVYGTWSALAALNAAGLDHD-HPAIRKAVAWLLSKQRDDGGWGEDGRSYWDEQGEGS-VSTPSQTAWALLGLMAVGE--R-HPAVA
RGVEYLIRTRTD-GLWDEEHYTAGFPRVFYLRYHGYRQFFPVWALARYRNLTAGN--
>tr|V5DL20|V5DL20_9GAMM Squalene--hopene cyclase OS=Methyloglobulus morosus KoM1 GN=shc PE=4 SV=1
---------------------------------------------------------------------------------------------LEAAINK
AQDKLLSLQDKRGYWVFDLEADCTIPSEYIMMMHYLD-IDE-P---LQAKIAVYLRSRQSKDGSYPLFTH-GGDISCSVKVYYALKMAGDSVDAP---HM
TSLRDWILQQGGAAKANVFTRIALAIFKQLPWRGVPFIPPEIMLFPKWFPFHLDKVSYWSRTVMVPLFILCSLKATAKN-PNI----LELFVTHPDERHY
---------FP----KIF--LGLDKFG-RW----AEPF-PTQIHDRAIEKAKDWIVERNGEDGLGCIFPAMVYESLLLLYPKDH--EYIVTARKAIDKLL
ITDDM-AFCQPC-VSPVWDTALTALALQEVDK--Q-ASSLTKAYDWLKSVQLSD-EPGDWRVRPHLAGGGWAFQYANPHYPDVDDTAVVAFAMADS--N-
-----LPNLDESIHRATRWIEGMQSKNGGYGAFDVDNTYYY---LNPFADHGAL-LDPPTADVSARCAMLMAKAGKE---SG--MYQAALERSINYLRSE
QEKDGSWFGRWGTNYIYGTWSVLLGLEQTNLPKT-DVLYLNAVKYLKAKQREDGGWGEDNYSF--YGK-YH-FSTAFQTAWAVLGLMAAGE--R-SAEVK
AGIDFILRNQQA-GVWNDPCFTAGFPRVFYLKYHGYDKFFPLWALARYRNELDKQ--
>tr|Q60AN5|Q60AN5_METCA Squalene-hopene cyclase OS=Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath) GN=sqhC PE=4 SV=1
---------------------------------------------------------------------------------------------LDAAIRQ
AKDRLLSLQHLEGYWVFELEADCTIPAEYILMMHFMD-IDA-A---LQAKIANYLRSHQSADGSYPLFRG-GGDISCTVKVYYALKLAGDSIDAP---HM
KKAREWILAQGGAARSNVFTRIMLAMFEQIPWRGIPFIPVEIMLLPKWFPFHLDKVSYWSRTVMVPLFILCSHKVTARN-PSI----RELFTVDPQERHY
---------FD----KAI--LALERFG-RM----LEPL-PKAVRKKATQKAFDWFTARNGVDGLGAIFPAMVYEALDFLVPPDD--ERRRLARESIDRLL
FQGDS-VYCQPC-VSPIWDTALTSLTLQEVAR--HLDAALSKGLKWLASKQIKD-APGDWRVRAGLEGGGWAFQFGNDYYPDVDDSAVVAHALLGS--E-
-----DPSFDDNLRRAANWIAGMQSRNGGFGAFDADNTYYY---LNPFADHGAL-LDPPTADVSARCAMFLARWVNR---QP--ELRPVLERTIDYLRRE
QEADGSWFGRWGTNYIYGTWSVLLAYEAAGVPND-DPSVRRAVAWLKSIQREDGGWGEDNFSY--YGR-FH-TSTAFQTGFALIALMAAGE--G-SPEVQ
AGVDYLLRQQRP-GFWNDECFTAGFPRVFYLKYHGYDKFFPLWALARYRNERYAL--
>tr|A0A0D5MSD1|A0A0D5MSD1_BURGL Squalene-hopene cyclase OS=Burkholderia glumae LMG 2196 = ATCC 33617 GN=shc PE=4 SV=1
---------------------------------------------------------------------------------------------LDAAILR
GRDALAQRQSADGSWCFELESDATITAEYILMMHFMG-IDE-A---RQARMARYLRGIQRTHGAWDLYVD-GPDVSCSVKAYFALKAAGDSEDAP---HM
ARARETILKLGGAAKSNVFTRILLATFGQVPWRATPFMPVEFVLFPKWVPISMYKVAYWARTTMVPLLVLCSLKARAKN-PRV----RELFVTAPEERHY
---------FA----NLF--LGIDRAL-RP----LDAL-PKALRRRAIRHAEAWCAERNGEDGMGGIFPPIVYQMMDVLYPEDH--PLRRDCENALDKLL
ERPDGSVYCQPC-LSPVWDTAWSTMALEQARAVPDLQRCIAASYEWLAGKQVTQ-VRGDWVEAAATPAGGWAFQYENPYYPDIDDSAVVAAMLHRRGRLL
ARSTGTDPYAQVVARGLDWMRGLQSRNGGFGAFDADCDRLY---LNPFADHGAL-LDPPTEDVSGRVLLCLGVTGRD----E---DKPALARAIEYVKRM
QRADGCWWGRWGTNYIYGTWSVLAGLALAGENPS-QPYIARAIAWLRACQNADGGWGETNDSY--LGTNGG-ESASNVTAWALLAQMAFGD--Q-SESVQ
RGIRYLLSVQQA-GFWWHRSHNAGFPRIYYLKYHGYTAYFPLWALARYRRLSQAG--
>tr|A0A0D5EB96|A0A0D5EB96_9BURK Squalene-hopene cyclase OS=Burkholderia ubonensis MSMB22 GN=shc PE=4 SV=1
---------------------------------------------------------------------------------------------LDAAILR
GRDALSGLQQPDGSWCFELESDATITAEYVLMMHFMD-IDE-D---RQARMARYLRAIQRTHGAWDLYVD-GPDISCSVKAYFALKAAGDSEHAP---HM
IRAREAILKLGGAARSNVFTRILLATFGQVPWRAAPFMPVEFVLFPKWVPISMYKVAYWARTTMVPLLVLCSLRARARN-PRV----AELFVTPPDERHY
---------FP----RLF--LALDRTV-RH----LEPL-PRRLRQRAIRHAEAWCAERNGEDGLGGIFPPIVYQMMEVLYPEDH--PLRRDCEDALEKLL
TRADGSVYCQPC-LSPVWDTAWSTMALEQARGATPLDARIARAYDWLATRQVND-LEGDWREAPGTQPGGWAFQYANPYYPDIDDSAVVTAMLDRRGRAQ
ARTSGENPYAERVTRALDWMRGLQSRNGGFGAFDADCDRLY---LNPFADHGAL-LDPPTEDVSGRVLLCFGVTKRP----A---DRAAAARAIEYVKRT
QQPDGSWWGRWGTNYLYGTWSVLAGLALSGEDKS-QPYIARALDWLRAHQHADGGWGETNDSY--LATNYG-ESTSNCTAWALLAQMAFGD--Q-SDSVR
RGIAYLLSVQQD-GFWWHRSHNAGFPRIFYLKYHGYTAYFPLWALARYRRLASAQ--
>tr|A0A037V0B8|A0A037V0B8_9RHIZ Squalene--hopene cyclase OS=Rhodomicrobium udaipurense JA643 GN=T281_01140 PE=4 SV=1
---------------------------------------------------------------------------------------------LEERINA
ASSALLSYQREDGHWCFEFEADATIPAEYALLVHYLGEPNL-E---REAKIATYLRRIQGEHGGWPLFHK-GFDMSASVKAYFALKMIGDDIDAP---HM
VRAREAILSRGGAEMANVFTRILLALFGVVTWRAVPVMPVEIMHLPRWFPFHMSKVSYWARTVMVPLFVLGALKPVAKN-PRV----NELFHTNPKVGPR
---------PR----TFF--AGVDACL-RV----VDPM-PKRSRKSAIGKAVAFVKERNGEDGLGAIFPAMAVMMYEALVPESD--PDRAIARYSIEKLL
ETE-NEVYCQPC-VSPVWDTGLAAHALLETGGE-A--EAAHRGLEWLKPLQVLD-VKGDWADKPDVRPGGWAFQYANPHYPDVDDTAVVALALDRAAHLP
---GSNANFEQSVARAKEWVSGLQSKNGGWGAFDADNTCYY---LNPFSDHGAL-LDPPTVDVSARCVSMLAQLGEK----P--DTNAVMKRGIDYILSE
QEKDGSWFGRWGSNYIYGTWSALCALNAAGLAHD-SAAMRRAVAWLVSIQNEDGGWGEDGSSYKL-GYEKS-PSTASQTSWALLGLMAAGE--D-NPAVK
RGIAWLVANQNE-GTWKEERHNAGFPRVFYLIYHGYSKYFPLWALARYRNLTSGN--
>tr|G3IVQ6|G3IVQ6_9GAMM Squalene-hopene cyclase OS=Methylobacter tundripaludum SV96 GN=Mettu_0576 PE=4 SV=1
---------------------------------------------------------------------------------------------LDSAIDR
AKAQLIRRQSQEGYWVFELEADCTIPSEYILMMHYMD-IDG-A---LQAKIANFLRTQQSTDGSYPLYKG-GGDISCTIKVYYAMKMAGDSIQAV---HM
VKARDWILAQGGGARANVFTRIMLAMFEQIPWRGVPFMPVEIMLLPKWFPFHLDKVSYWSRTVMVPLFILCTYKVKARN-PLI----AELFVTPPDERNY
---------FS----KAI--LVVERMG-RL----MEPL-PGFVRRKATAKARDWFMERNGYDGLGAIFTAMVYEAMDYLIPPDN--EQRRIARAAIDRLL
INEDM-AYCQPC-VSPIWDTGLVALVLQEVDR--HTRQALKSALSWLAGKQLKD-EPGDWRIRPNLPGGGWAFQFGNSYYPDVDDTAVVALALIQA--D-
-----DQAFAENIDRAGIWIAGMQSSNGGYGAFDADNTHYY---LNPFADHGAL-LDPPTVDVSGRCIMFLGKLVNQ---HP--EYRAVIDNCIDYLRNE
QETDGCWFGRWGTNYIYGTWSVLIGFESAGVAKQ-DPSIRKAVVWLKSKQRGDGGWGEGNYSY--IGE-FD-VSTAFQTALALLALLSAGE--G-CPEVE
AGVNYLLKSQQA-GFWKDESFNAGFPKVFYLKYHGYDKFFPLWALGRYRNELWVS--
>tr|Q39LV3|Q39LV3_BURL3 Terpene synthase/Squalene cyclase OS=Burkholderia lata (strain ATCC 17760 / LMG 22485 / NCIMB 9086 / R18194 / 383) GN=Bcep18194
---------------------------------------------------------------------------------------------LDTAIAR
GRDALVRLQQPDGSWCFELESDATITAEYILMMHFMD-IDD-L---RQEKMARYLRANQRTHGGWALYVD-GPDVSCSVKAYFALKAAGDSEHAP---HM
VRARDAILKLGGAARANVFTRILLATFGQVPWRAAPFMPIEFVLFPKWVPISMYKVAYWARTTMVPLLVLCSLKARARN-PRI----RELFVTPPDERQY
---------FP----KLF--LALDRTV-RH----VEPL-PKGLRQRAIRHAEAWCAERNGEDGLGGIFPPIVYQMMEVLYPDDH--PLRRDCENALEKLL
TRPDGSMYCQPC-LSPVWDTAWSTMALEQARGVAVLDERITRAYDWLAERQVND-LRGDWIEAADVQPGGWAFQYANPYYPDIDDTAVVTAMLDRRGRTH
ANADGTNPYATRVARALDWMRGLQSRNGGFGAFDADCDRLY---LNPFADHGAL-LDPPTEDVSGRVLLCFGVTKRA----D---EHASLARCIDYVKRT
QQPDGSWWGRWGTNYIYGTWSVLAGLALAGEDKS-QPYIARAIEWLRARQHADGGWGETNDSY--LGTNGG-ESTSNFTAWALLAQMAFGD--E-SDSVK
RGIAYLQSVQQE-GFWWHRSHNAGFPRIFYLKYHGYTAYFPLWALARYRRLAGVA--
>tr|A0A0A6QBW0|A0A0A6QBW0_9BURK Squalene--hopene cyclase OS=Burkholderia sacchari GN=NH14_15680 PE=4 SV=1
---------------------------------------------------------------------------------------------LDAAIVR
GRDALARRQHPDGSWCFELESDATITAEYILMMHFMA-IDT-A---RQEKMARYLRAIQRTHGGWDLYVD-GPDVSASVKAYFALKAAGDAPDAP---HM
VRAREAILKLGGAAKSNVFTRILLATFGQVPWRATPFMPIEFVLFPKWVPISMYKVAYWARTTMVPLLALCSLKAKAHN-PHV----PELFVTPPDEREY
---------FP----RLF--LALDRTV-RH----LEPL-PQSWRKRAMKHAEAWCAERNGEDGMGGIFPPIVYQMMEVLYHENH--PLRRDCENALEKLL
ERPDGSMYCQPC-LSPVWDTAWSTMALEQALAVPDLQQQITRAYDWLATRQVDD-LTGDWIEVPDVQPGGWAFQYANPYYPDIDDSAVVAAMLHRRGRSI
ERATGTDPYAARVTRALDWMRGLQSRNGGFAAFDADCDRLY---LNPFADHGAL-LDPPTEDVSGRVLLCFGVTGRE----E---DKAALARAIDYIKAT
QQPDGSWWGRWGTNYIYGTWSVLAGLALAGEDPS-QPYIARALAWLRSRQHADGGWGETNDSY--LGTNGG-ESASNFTAWALLAQMAFGD--E-SESVR
RGIAYLLSVQDS-GFWWHRSHNAGFPRIYYLKYHGYTAYFPLWALSRYRRLVADG--
>tr|G4SWI8|G4SWI8_META2 Putative squalene--hopene cyclase OS=Methylomicrobium alcaliphilum (strain DSM 19304 / NCIMB 14124 / VKM B-2133 / 20Z) GN=shc P
---------------------------------------------------------------------------------------------LNDAITC
AKARLLELQNEEGYWVFELEADCTIPSEYILMMHFMG-IDA-T---HQAKIVQYLHEQQDRDGSYPLYKG-GGDLSCTIKAYYAMKLAGDSIQAQ---HM
VKARRWILARGGGAKANVFTRIMMAMFEQIPWRGVPFIPVEIMLLPKWFPFHIDKVSYWSRTVMVPLFILCTYKVKARN-PNV----SELFITQPEEKNY
---------FA----KSI--LAADRMG-RL----MEPL-PGFVRRKATIKARDWFMSRNGYDGLGAIFTSMVYEAMDYLIPADD--ERRRIAREAIDRLL
VKPDK-AYCQPC-VSPVWDTGLAVLVLQEVDR--RAEQSLTKALNWLAGRQLSN-EPGDWRVRPNLPGGGWAFQFGNSHYPDVDDTAVVALAMIES--G-
-----DREFAENIERAGVWIAGMQSANGGYGAFDADNTHSY---LNPFADHGAL-LDPPTADVSGRCVMFLSKLVDR---QP--EYRAVIDTCITYLRNQ
QEADGSWFGRWGTNYIYGTWSVLTGFESAGISKH-DSHIRKAVVWLKSKQRADGGWGEDNDSY--VGE-SE-TGSAFHTALALLALMSAGE--G-CPEVK
SGINYLLKNQQD-GFWKDDGFNAGFPKFFYLKYHGYEKYFPLWALGRYRNECGDF--
>tr|M2YFT8|M2YFT8_9PROT Squalene cyclase OS=Magnetospirillum sp. SO-1 GN=H261_00290 PE=4 SV=1
---------------------------------------------------------------------------------------------LDRAVNE
SAEALLKQQRDDGHWVFKLEADATIPAEYVLYLHYLD-RDP-E---LEKRIGVYLRDIQEEHGGWPLFHR-GLNISASVKAYFALKAIGDDIDAP---HM
KKARDAILAHGGAATANVFTRTLLALFGQIPWKGVPIMPVEIMLLPRWFPFHMDKVSYWSRTVIAPLTVLMTTRPKARN-PLI----QELFVTPPEVTNW
---------YL----YLF--RGIDMVL-QK----VYRF-PKGLQKKAIDKAVAFVDERNGEDGLGAIFPAMVVWMYDVLIPADD--PRVVIAKQSIRNLV
EE--ERAWVQPC-LSPIWDTALATHAILEVGTP-EADAAARKAADWMVARQITD-VVGDWAVRPGLAPGGWAFQYNNPHYPDVDDTAVVMAALDRID---
-----PVKYAEPIEKGKVWVQGMQSEGGGWGAFDAENTSYY---LNPFADHGAL-LDPPTADVSARCVSVLSVLGE-----R--GKDKVAHEGVDYLLRE
QEKDGSWFGRWGTNYVYGTWSSLCALNAAGLPHD-HPAFRRAVKWLESKQRDDGGWGECGRSYWDQRGEGG-PSTPSQTAWAVLGLMAAGE--K-SQAVA
RGIDYLIRTRNA-GLWDEEHYTAGFPRVFYLRYHGYRQFFPVWALARYRNLTTGN--
>tr|F9ZWL2|F9ZWL2_METMM Squalene-hopene cyclase OS=Methylomonas methanica (strain MC09) GN=Metme_2461 PE=4 SV=1
---------------------------------------------------------------------------------------------LDDAIKL
ATAELLSLQNQQGYWVFELEADCTIPAEYILMMHYLD-IDS-V---LQRKIAHFLRGHQNPDGSYPLYKG-GGDISCTIKVYYALKLAGDDIQSP---TL
HSAGEWIRHRGGAAKANVFTRIMLAMFEQVPWRAAPFIPVEIMLLPKWFPFHIDKVSYWSRTVMVPLSILCSYKVKARN-PSI----AELFLIPPDETHY
---------FS----KAI--LLLDRLG-RR----LERF-PDSIRRKATAKACDWFMARNGIDGLGAIFTAMVYEVMDYLVPVDD--PQRQIARAAIDKLL
VKGDT-AYCQPC-VSPIWDTGLAALTLQEVDR--HTRQALQAALHWLAGKQLRD-EPGDWQIRPSLAGGGWAFQFGNSYYPDVDDTAVVAYAMLQA--D-
-----DVKYAGNIQRAAGWIAGMQSRNGGYGAFDADNTHYY---LNPFADHGAL-LDPPTADVSGRCIMLLGKLAVR---HL--EYGTVVKDCLAYLRAQ
QESDGSWFGRWGTNYIYGTWSVLYGYEAAGIPRN-DPSIQKAVLWLKAKQRADGGWGEDNLGY--VGE-AD-NSTAFHTALAILALLSAGE--D-SREVE
TGVHHLLKTQRA-GFWRDDSFNAGFPKFFYLKYHGYDKFFPLWALARYRNDRYAA--
>tr|V5C8M3|V5C8M3_9GAMM Squalene--hopene cyclase OS=Methyloglobulus morosus KoM1 GN=shc PE=4 SV=1
---------------------------------------------------------------------------------------------LDSAIAK
AKVPLLGMQHEAGYWVFELEADCTIPSEYILMMHFMD-IDE-V---IQVKIANYIRSQQNADGSYPLYKG-GGDISCTIKAYYAMKMAGDAVNAT---HM
VKAREWILGKGGAAKGNVFTRIMMAMFGQIPWRGVPYMPVEIMLLPKWFPFHLDKVSYWSRTVMVPLFILCTYKVKARN-PHI----AELFVIPPDERNY
---------FA----KTI--LIAERIG-RL----MEPL-PSLIRRRATGKARDWFLERNGYNGLGAIFTAMVYLAMDYLIPVDN--EQRQVARAAIDRLL
IKDDM-AYCQPC-VSPIWDTGLSSLVLQEVDR--YTQKAIRSALHWLAAKQLKD-EPGDWQNRPNLPGGGWAFQFGNSYYPDVDDTAVVALAMVQA--D-
-----NRKFAENIGRAGIWIAGMQSTNGGYGAFDADNTHHY---LNPFADHGAL-LXPPTADVSGRCVMFLAKIVNQ---HP--EYQTVIDNCIAFLRKE
QETDGSWFGRWGTNYIYGIWSVLIGFETAGVPRN-DPSIRKAVTWLKSKQRADGGWGEDNYSY--IGV-FH-TSTAFHTALALLALLSAGE--G-CVEVE
SGVNYLLKNQQS-GFWKDKSFNAGFPKVFYLKYHGYDKFFPLWALARYRNECLTV--
>tr|K9GV72|K9GV72_9PROT Squalene--hopene cyclase OS=Caenispirillum salinarum AK4 GN=C882_0815 PE=4 SV=1
---------------------------------------------------------------------------------------------ATLGTAE
ATEALLSRQKDDGHWVFELEADVTIPAEYILLCHYLGEIDP-G---LCQRLGDYIRGARTANGGWPLFHE-GMDLSASVKGYYALKACGDDIDAP---HM
VEARTAILRAGGAERANVFTRILLALFGQVPWRAVPTMPVEIMTLPRWSPFHLDRVSYWSRTVIVPLLVLMACKPQARN-PKI----QELFNTPPEVEDW
---------HH----RFF--KLLDAAV-RR----AEPL-PADNRRRAIAKAVNWVEERNGEDGLGAIYPAMAVMMYDALYSREH--PSYMTARRSIEKLV
DR--GATYVQPC-LSPVWDTALTVQALLEVNTP-AAQEACIRGLDWLAERQILD-TVGDWAVRPNVKPGGWAFQYANPHYPDVDDTAVVVMAMHRAD---
-----PVRYATAIERALHWIRGMQSENGGWGAFDADNTHHY---LNPFADHGAL-LDPPTADVSARCVGMLAQLGT-----G--PGDPVMDAGLRYLRRE
QEADGSWFGRWGTNYVYGTWSVLSAFNAAGVDAE-DLTVRRAVQWLKDQQNEDGGWGESGATYWR-RHERC-ESTASQTAWAMLGLMAAGA--D-DPSVA
RGAAYLAENQGE-GLWPEDPYTAGFPRVFYLRYHGYPAFFPLMALARYKALNEGN--
>tr|J7QP20|J7QP20_METSZ Uncharacterized protein OS=Methylocystis sp. (strain SC2) GN=BN69_1707 PE=4 SV=1
---------------------------------------------------------------------------------------------LETSIQN
AKRALLSLGKGEGHFCFELEADTSLSAEYVLMRHFRGEVDA-E---LERKIAVYLRRCQGDHGGWPLYQD-GFHISSSVKAYFALKMIGDDVDAP---HM
ARARAAILAYGGAARSNVFTRALLALYGEIPWRGVPVMPVEIMLLPKWFPFHLDKISYWGRTVLVPMLVLMTKKPRAKN-PRI----GELFTTPPDVKVW
---------PK----NIF--GRIDKLL-RL----IEPH-PSGPRERSIELAMEWTTERNGVDGLGGIFPSMVLLMYDVLVPDAD--ARKKQAREAIERLL
VTD-TEVYCQPC-VSPVWDTCLTAHTLLETGDE-D--EQARQACEWLAPLQVLD-VKGDWAARPNVRPGGWAFQYANAYYPDVDDTAVVVTAMDRLTAND
---AS-RPYDERIARAKEWIVGMQSKNGGWGAFDADNTCHY---LNPFADHGAL-LDPPTADVSARCVSMLAQLGDT----I--DSSECLKRGVDYLLKE
QEKDGSWFGRWGANYIYGTWSTLCALNAVGLPHA-HDAYRRAVAWFVAIQNGDGGWGEDLSSYKL-GYEKA-PSTASQTAWALLALMAAGD--D-HPAVA
RGIAYLQSTQND-GLWNEARFTAGFPRVFYLRYHGYGKFFPLWALARYRNLRRAN--
>tr|B0U917|B0U917_METS4 Squalene-hopene cyclase OS=Methylobacterium sp. (strain 4-46) GN=M446_6347 PE=4 SV=1
---------------------------------------------------------------------------------------------VERRVTL
ASKALMRLANADGHWCFELEADATIPSEYILYHHFRGSPTA-E---LEGKIAAYLRRTQSQHDGWALIHD-GFDMSATVKAYFALKMVGDPIDAP---HM
RRARDAILRRGGAAHANVFTRIMLALYGEVPWTAVPVMPVEVMLLPRWFPFHLDKVSYWARTVMVPLFVLQAKKPRARN-PRI----RELFVEAPEVKRW
---------PA----PVF--AAIDKVL-QK----VEGF-PAGSRARAIDKAVAFVSERNGEDGLGAIFPAMVVLMFEALYPDDH--PFAVTARSSVEKLV
VKE-HEAYVQPC-LSPVWDTALAAHALMEAGGT-E--RHAKRAMDWLKPLQVLD-IKGDWAAKPDVRPGGWAFQYANPHYPDLDDTAVVVMAMDRVQSRR
SPGPDAADYGLSIARAREWVEGLQSRDGGWAAFDADNTYHY---LNPFSDHGAL-LDPPTADVTARCVSMLSQLGET----R--ETCPPLDRGVAYLLAD
QEADGSWYGRWGMNYIYGTWSVLCALNAAGIDPA-CEPVRRAVTWLTAIQNPDGGWGEDASSYKL-GYERA-PSTASQTAWALLALMAAGE--D-NPAVA
RGINYLTRTQGA-GLWAEDRYTAGFPRVFYLRYHGYAKFFPLWALARYRNLQRGN--
>tr|H6SNY5|H6SNY5_RHOPH Rhodospirillum photometricum DSM 122 draft genome sequence OS=Rhodospirillum photometricum DSM 122 GN=RSPPHO_00431 PE=4 SV=1
---------------------------------------------------------------------------------------------LNAIIDE
ATRWLTDRQNADGHWVFELEADATIPAEYILLNHFLD-IDD-E---REHRLARYLRRIQGKHGGWPLFHD-GFDMSASVKAYYALKLVGDSVEAP---HM
RRARAAILAHGGAERANVFTRFTLAMFGQVPWRACPVTPIEAVLLPRWSPFHTTKVSYWSRTVMTPLMVLYSRRARAIN-PRI----QELFRRNPEVRDW
---------MK----ETL--IQVDKVL-RV----IEPA-HRLFRGKAEAWALDFIEKRNGKDGLGGIYPAIALMVYQTLYAKDH--PHYRIAREAVDGLC
RH--DIEYVQPC-LSPVWDTCLASHALQEAGLK-ANDPAIAKSNEWLRGRQVLS-VVGDWAHRGHLEPGGWAFQYWNDYYPDVDDTAVVVMALDRAN---
-----EGDVREAIKRAEAWIKGMQSANGGWGAFDAENNTEF---LNPFADHGAL-LDPPTVDVSARCLGMLAQIGC-----P--LTDPVVQKGVEFLWSE
QEEDGSWFGRWGTNYIYGTWSALNALNAVDVDMQ-DPRVRKAVQWLKDRQQPDGGWGEDCATYWK-KGEVK-GSTPTQTAWAVLGLMAAGE--D-SPEVE
RGIRYLLDAPRD-GKWQEELYNAGFPRIFYLRYHGYSAYFPLWALARYRSLSQGN--
>tr|B0YBJ5|B0YBJ5_ASPFC Terpene cyclase/mutase family member OS=Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) GN=AFUB_086820 PE=3 SV=1
---------------------------------------------------------------------------------------------IKQAIKL
SGQHSRGEMHSDGHWCGEVKTNATTSAEHVLLCQALGINLDA----DREAFISWFRCTQGADGGWSTAPDQAGDISVTVEAYLALKILGLSEDDA---AM
RRARDFAIAAGGVAKVRIFTRIYLALFGLFPWAAVPELPPELILLPSRVPVSIYHWSAWARATVVPLLIISHHRPIYAL-PGG---KDELWCDPQNKM--
-----------IPYNSIF--TLADSIL-HR----LDGLR---FRRFALQKCVDWILEHEDMGDIGDIMPPLHMLALRLEYPLHS--GPIHRGLEAIERFA
YRDK--KRIQTT-VSAFWDTSLMLIALGDAGMA--SKPWLTRSLGWLQQHQRLG-NYGDWKVNHGLKAGGFSFGYFNTWYPDVDDTASAVLAMIRQDE--
-----RLVHSASVLDALNWLLGMQNTDGGWGAFDRDNDKHF---LNPFSDMDAL-CDPSTPDVTGHVLEAFGLFLALSKDALADRVVSASRRAIRYLSDT
HVLSRGWYGRWGCNYIYGTSAVLCALAYFGSENDLKDAINQAIRWLETVQNPDGGWGETVDSYKDRAGSG--PSTASQTAWAIMALLPYLPPS--TEVIQ
RGMEYLLRTQTKTATWHEKAYTAGFPKYFYMGYSLYAHYFPMMALGRYAYPCPAW--
>tr|A0A0D7A6W5|A0A0D7A6W5_9AGAR Squalene cyclase OS=Fistulina hepatica ATCC 64428 GN=FISHEDRAFT_48916 PE=4 SV=1
---------------------------------------------------------------------------------------------VMHAVQL
AVNNSFEQMKPDGHWCGELRSNATITAEYVFLRAALGLDLTV----DSAALSKWLWAEQKADGSWGIAPFYPGDVSTTTEAYLALKILGTPMDHP---SM
ARAREFIRSAGGVAKVRIFTRIYLATFGLFPWDVVPQLPPEFILMRSWAPINIYHLSSWARSTVVPLLILSHHRPIFAL-PN----RDELWCDPTNKM--
-----------VPYSCVF--AVADNIL-HS----LGGLS---LRSLARRRCVAWILEHEQTGDWAGIFPPMHIIALMLEFSLQG--SAIQRGLAAVEAFA
WIDE--KRMQAC-VSPVWDTLLMTTALCDAGVR-VQDERLCQAVRWVQARQVFG-PEGDWRIRPHMTGGGFSFEYCNNWYPDVDDTAEAVLTFLKQDP--
-----RSVGSASVIVAVGWILGMQNKDGGWAAFDWGNNKLF---LNPFSDMDSL-CDPSTADVTGHVLEMFGLLVQCAASSLMQRVDDAATRAISYLAST
QEPSGAWFGRWGVNYIYGTSNV------------LPSLVGPAIKWLRYVQHSDGSWGEALDSYGVSCGSS--ISTPSQTAWGIMGLLAHFPPT--DLAIQ
RGITNLLHTQTVRATWPEEAYTGGFPKFFYIGYAMYSHYFPLMALGRYVSAVNAT--
>tr|A2Q7M8|A2Q7M8_ASPNC Terpene cyclase/mutase family member OS=Aspergillus niger (strain CBS 513.88 / FGSC A1513) GN=An01g01290 PE=3 SV=1
---------------------------------------------------------------------------------------------ACDATKL
AGTYALRQVREDGHWYGEMKSNATITAEYVFLAQALGFSIEE----DRDDLIKYFLSEQNTDGSWSLAYDFPGDVSVTAEAYFALCLLGLDRSHP---AM
ASAREFTLSKGGIAKVRVFTRMFFACFGLFPWSAVPELPAELILLPAAAPMSIYQLASWARATVVPMLVIRHHRPIYAL-PN----RDELWVDPTDKM--
-----------VPYSFGF--TLADNIL-KA----LGGLR---SRKIALRHCVAWILEREPEGDIGGIFPPLHLFALALEYGLES--SPVRRGIDALQTYA
WRDS--LRIQGC-ISPILDTILMTIGLIDSSLP-AESPLVARSSRYLKAHQQLG-NEGDWRVNGNVPSGGFNFEYFNSWYPDIDDTAAAILAMVKQDP--
-----NLLDLGPILSAVQWILGLQNDDGGWAAFDRENNYLF---LNPFSDMDSF-CDPSTADVTGRVIECFGL--NGKNRFFIDDMSSATERAIDFLSTE
QEADGSWYGRWGSNYIYGTSAVLCGLVYHLEGWDTKVDTHAALDWLKRHQNPDGGWGERLESYYELAGNG--PSTASQTAWALMGLLAYLAPT--DESIT
RGIQYLSRTQIKEGSWKEDHYTGGFPNHFYLCYTLYSQYFPMMALGRYTSLSGYR--
>tr|B6HQG5|B6HQG5_PENCW Terpene cyclase/mutase family member OS=Penicillium chrysogenum (strain ATCC 28089 / DSM 1075 / Wisconsin 54-1255) GN=Pc22g2419
---------------------------------------------------------------------------------------------VEHALKL
SNDYALGLVHPDGHWYGEMNTNVTVTAEYVFLRQALRLDLKT----DIAAYCHYLLSQQNSDGSWGLAPEYPGDVSTSTEAYLALKILGTSPHTP---AM
RNARAFVLKAGGIARVRIFTRIFLATFGLFPWSAVPELPVELMLLPSICPINIYKFASWARGTIAPLLIICHHQPVYSL-PN----KDELWVDCTNKS--
-----------VPYGLAF--GVLDKVL-YQ----LNGLR---IRAYARKQCIQWILEREKTGDWAGIFPPMHMYAFTLEYKLDD--DPVRLGFQALERFA
WEDE--KRIQAC-VSPVWDTALMTIGLCDAMSP--NKQTIDHALAWIRARQLLE-PRGDWRVRPQLAPGGFSFEYENSWYPDVDDTAAIILAQVKHDN--
-----GSIGSNSVIAAATWILGMQNPDGGWAAFDVENDKLF---LNPFSDMDSL-CDTSCADITGRILEAYGLMMMKYFDPLLHTLRAACMRGMHYLAST
QEPNGSWYGRWGCNYIYGTSHVLCGLAYFVEK-RVCVMVKSALQWLKSRQNDDGGWGESLLSYQSRE-QQ--ASTPSQTAWALMGLLSHLPVT--DDAIE
RGIRYLVSSQRPESSWPQAEYTGGFPNHFYLGYDYYRHYFPMMALGRYLQGSRGL--
>tr|I8TE74|I8TE74_ASPO3 Terpene cyclase/mutase family member OS=Aspergillus oryzae (strain 3.042) GN=Ao3042_11354 PE=3 SV=1
---------------------------------------------------------------------------------------------AGLTLQR
SMDYAYNVVRSDGHWCGEMSSNVTITAEYIFLRQALGLDLKT----DGAAYCRHILSQQNSDGSWGLAPEYPGDVSTTTEAYLALKMLGLSTDAP---AM
QQAKAFVLNAGGVAKVRVFTRIFLATFGLFPWKAVPQLPVELILLPSACPINIYKFASWARGTIAPLLIICHHQPVYAL-PN----VDELWQDPTNKS--
-----------EPYSLTF--SLLDKLL-YQ----LNGLR---LRSYALKQCMKWILEREPTGDWAGIFPPMHVYAFVLEYKLED--PPVRLGIEALENFA
WEDA--KRVQPC-VSPVWDTTLMSIALSDAATP--NHQIVDRAIQWIRDRQLLE-PRGDWRVRPRLAPGGFSFEYTNSHYPDIDDSAAIILAQVKHDP--
-----ISANSSSVIAAATWILGMQNPDGGWAAFDVENDKLF---LNPFSDMDSL-CDTSCADITGRILEAFGLLIRRVPFQLLPAIRAACRRGVRYLAST
QEANGAWFGRWGCNYIYGTSHALCGLAYFLQEDQVPAMVQPALQWLKSQQNDDGGWGESLLSYQSRK-EQ--RSTASQTAWALMGLLAHLPHT--DIVIE
RGIRWLVSSQRPVSTWPEPVYTGGFPNYFYLGYDYYRHYFPMMALGRYLRGVQG---
>tr|A0A0B4H4A1|A0A0B4H4A1_9HYPO Terpene cyclase/mutase family member OS=Metarhizium guizhouense ARSEF 977 GN=MGU_08255 PE=3 SV=1
---------------------------------------------------------------------------------------------ARRSIDL
AIEHAWNSAQPEGYWIGEQLSNSSVTAEHVFFHQSLGHKLLA----DEALYVSYLLSQQQDDGSWPLAPYCPGDVSTTSEVYLALKILGLSPTST---QM
KKARQFIRKSGGVAKVRIFTRVYFAQFGLFPWDAVPQLPPEFILLPCLLPVNIYRLASWARATVIPLFIIRHHEPIYAL-PN----VDELWLEPDHKM--
-----------VAYSTFF--SLVDRVL-FW----VGGAI---SRQYALELCKTWIVEHEVQGDWAGIAIPMHLQALLLEYTLSD--SKIRRGLAALERFT
WRNK--KHLQPC-VSPTWDTVLMARGLCDAGVG-CKDGRLQRAIEWIKSRQLLD-SHGDWSVNPNLAPGGFCFQYYNSWYPDVDDTAAVILAIVNHDR--
-----DAASGMVVTRAALWICGMQNRDGGWGAFDRNNDSLW---LNPFSDMNAM-CDPSSADVTGRVLEAFGQMMRESDAGLVHRISAACKAALVYLANT
QETTGAWYGRWGVNYIYGTSNVLCGLQFFRDGNGVQDMIASAAAWLQSHQNQDGGWGETVDSYKDLAGQG--PSTPSQTAWAIMGLLAAQGPN--DKSIT
AAIEYLLRTQTTCGTWPEDRHTGGFPNHFYFGYAFYRHYFPLMALGRYARAVCT---
>tr|A0A0D2AMC5|A0A0D2AMC5_9PEZI Verruconis gallopava strain CBS 43764 unplaced genomic scaffold supercont1.37, whole genome shotgun sequence OS=Verruconis gall
---------------------------------------------------------------------------------------------VRTAIRL
AAERAWNVMHADGHWCAEIRANVTVTAEHIFFYASLGKPPPG----GYAPFQRFIQSQQNPDGSWGLAPSYPGDVSTSCEAYLALKMCGLSVACE---TM
QRARAFILSKGGVAKVRVFTRIFLAMFGLFPWSAVPNLPPEAILLPAWCPLNVYKLASWARSTVIPLLLIRHHKPIYRI-PG----GDEIWLDPESKS--
-----------VPYSLLF--AIGDRILS--------------LRRLARKRCVDWIIEHESQGDWAGIVMPMIVQALLLEYSIVD--PVIDRGLTAIERFA
YEDE--RRVQAC-VSPHWDTVLMITSLCETASA--APKRLHRCVEWVTKRQQLV-EHGDWRINPQLRPGGFSFEYNNSWYPDVDDTAATVLALLKYNA--
-----RFVHSNTVLDAINWILGMQSKSGGWAAFDTNNDKLW---LNPFSDMDAL-CDPPTADITGRVLEAFGLAMDICRLPALDRMDAACDRGIAFLCRQ
QETDGSWFGRWGSNYLYGTSAVLCGLQRFVIDRDVRDMVGAAVEWIKTAQNADGGWGEDLMSYKDLAGRG--VSSASQTAWALMGLLSHLSSD--DESVA
KGIHWLLTSQTEAASWPEMAYTGGFPGHFYFGYDLYRHYFPMMALGRYLKRSDEH--
>tr|A0A072P7P2|A0A072P7P2_9EURO Terpene cyclase/mutase family member OS=Exophiala aquamarina CBS 119918 GN=A1O9_07730 PE=3 SV=1
---------------------------------------------------------------------------------------------VEHACHS
AQKYAYEDIKENNHWCGELICNAAITAQHIFFYLGIGRNPVP----DADAYRIYLLGDQNADGSWGLAPHEGGNISVSCEVYLALKILGESPDSA---EM
SRARQYILQCGGVAKVRMWTRIFFAQFGLFPWEAVPELPAELILMPSYAPMSIYRLSSWARATVVPLLLISHHQPVYAL-PN----WDEIWVNPAQKK--
-----------VPYGVLF--TAIDSGL-YW----LGGLR---FRRYSRKLCVRWLMSREKTGDLSGVVPPMYVQALILEFELED--PVIERAIEALERFT
WQDQ--KRLQAS-VSPVWDTALMIRAMCDTAAN-KTDKRLKDAVGWVKKYQILG-PEGDWRVNPHLPAGGFCFEYFNTWYPDTDTTAAAMLAFLHHDP--
-----AMVESAVVHRAALWICGMQNCDGGWAAFDTGNDKMW---LDPFSDMNAL-CDPSTPDVTGHMLEALGILLKLSNVNPMHEISCACQRAIHYLASQ
QESCGAWYGRWGANYIFGTFNVLCGLAFFAEHDEVQTMMASGAKWLSSVQNSDGGWGEGLNSYNDRAGRG--VSTPSQTAWAILGLLTVYNHT--EPAVN
SGVMHLLETQTDVASWPEDRHTGGFPGHIYMGYTLYRHYFPMMALGRYAEKMKKK--
>tr|G3YHC2|G3YHC2_ASPNA Terpene cyclase/mutase family member OS=Aspergillus niger (strain ATCC 1015 / CBS 113.46 / FGSC A1144 / LSHB Ac4 / NCTC 3858a /
---------------------------------------------------------------------------------------------IEHSLKL
ATEYALSSIRSDGHWCGELRSNVTITAEYIFLRHALGLDLRT----DNAAYCRYILSQQNCDGSWGLAPEYPGDVSTTTEAYLALKLLGTSPDMP---AM
QQARAFVRKAGGAEKVRVFTRIFLATFGLFPWDVVPQLPVELILLPSSCPINMYTLASWARGTIAPLLIICHHQPVYAL-PE-----DELWLDPTDKN--
-----------VPYGLAF--SVVDNLLYYY----LNGLR---LRSYARRKCIQWILEREPTGDWAGIFPPMHIYAFVLEYELND--PPVRLGIQALENFA
WEDE--KRIQAC-VSPVWDTALMSIGLCDAMSP--DKQILQQAITWIRNRQLLK-PCGDWRIRPKLAPGGFSFEYENSHYPDVDDTAAIILAQLKQDP--
-----QSVASDSVIAAATWILGMQNPDGGWAAFDVENDKLF---LNPFSDMDSL-CDTSCADITGRILEAFGLMMKRELPVLSPMLRHACIRGITYLAST
QESNGAWFGRWGCNYIYGTSHALCGLAYCMEDDKVSGLVAPALQWLKSKQNDDGGWGEPLLSYRTTQLQQ--QSTPSQTAWALMGLLAHLPLT--DPAIE
RGIRWLVCSQQPEASWPEAVYTGGFPNHFYLGYDYYRHYFPMMALGRYLQASQAQ--
>tr|A1CPZ2|A1CPZ2_ASPCL Terpene cyclase/mutase family member OS=Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1) GN=
---------------------------------------------------------------------------------------------ARTALTK
ATSYAWE-IISNRHWCGELESNVTVTCEHIFFLYVLYQHIDPD---EGSQYRQWLLSQQNADGSWGIAPNYPGDVSTSAEAYLALRIIGMSPDSP---EL
FQARTFIRAAGGLSKMRMFTRIFFAEFGLVPWTAIPQLPAEFILVPAHFPISIYRLASWARSNVVPLLIIAHHRPLYPL-PN----LDELWLDPATKP--
-----------LPYGFVF--TILDKAL-SY----LGGLR---TRGYARRRCIQWILQHEKAGDWAGIIPPMHIKALWLEYKLHD--EPIQLGLAAIERFT
WTDN--KRLQCC-ISPVWDTVLMIRALQDTPASLGSDPRIADALAWTAENQHRG-PEGDWRVQPNIPVGGWAFEYSNTWYPDIDDTAAAVLAFLTHDP--
-----ATARSRLVRDAVLWIVGMQNADGGWAAFDHENNRLF---LNPFSDMESL-CDPSTPDVTGRTIECLGMLRDLLMSHLLKIINTACARAIPYLIRT
QEATGAWYGRWAVNYVYGTCLVLCGLQYFKHDPTADTMATRAVKWLRQIQNSDGGWGESVLSYRERAGCG--PSTPSQTAWALMGLLTVCGGE--DRSVQ
RGVRHLVDTQDDIAAWTEREFTSGFPNHFYISYTLYRVYFPITALGRYLSLVEGG--
>tr|A0A017RZY2|A0A017RZY2_9EURO Terpene cyclase/mutase family member OS=Aspergillus ruber CBS 135680 GN=EURHEDRAFT_468348 PE=3 SV=1
---------------------------------------------------------------------------------------------VPESLRK
ATTYLQSQVRDDGHWCAEVKSNTTVTSEYITLLYALNLPVPD----GPEPWISWIVSEQKFDGSWGPAPDIPGDISETVEAYFALKILGLDPENQ---VM
RKAKSWILVNGGVARVRIFTRIYLACFGLFPWSSIPELPPEFIFMPVAAPCSIYYMASWARATVVPLLLISHHRPVFAL-PN----RDEIWCDRGIKN--
-----------VPYTVAC--TVVDKAL-RY----ANGMR---WRLAARRRCLEWILEREEDGGWAGIFPPMHVLALYLEHYSTDPKSPFQRGIAGLEGFI
WTDD--KRMQAC-VSPVWDTILSSIGLLDAGLP-GDNEYIVRSNAWLLARQDKDQSPGDWRANPNLIPGAISFEYFNKWTPDVDDTAALILAFVKKEP--
-----SSIDSDSVVRAIQWILGMQNADGGWGAFDRENNKLF---FNPFSDMESM-CDPSTADVTGRVIEAFGLVMEKHSQSIRDAMKESANRGIDYLFRE
QEQSGSWYGRWGSNYLYGTSNVLCGLSNAHFIDNRNESIKRGVDWLVNVQNTDGGWGECLETYARLAGQG--KSTASQTGWALMGVLTLLAVT--DITVR
RGVQYLLSTQREDGAWIEREFTGGFPNHFYLGYVYYPHYFAMMGLGRYASLCGLK--
>tr|A0A0C1C3U2|A0A0C1C3U2_9EURO Terpene cyclase/mutase family member OS=Aspergillus ustus GN=HK57_00460 PE=3 SV=1
---------------------------------------------------------------------------------------------AQTAIDK
ATAYAWS-IFSNNHWCGELESNVTVTCEHIFFLYILYQRIDPA---EGNQYTKWLLSQQNTDGSWGIAPNHPGDVSTSAEAYLALKILGLPIDGR---EL
SAARRFILSQGGLSKMRMFTRIFFAEFGLVSWTQIPQLPAEFILVPASFPITIYKLASWARSNVVPLLIIAHHRPLYAL-PN----QDELWLDPDNKA--
-----------LPYGFLF--TIMDKAL-SY----LGGLR---TRSLARRRCISWILSHEKAGDWAGIIPPMHIKALLLEHSIHS--DPIQRGLAAIERFT
WTDT--KRLQCC-ISPVWDTVLMIRALRDCR---IVDPRINDAVAWTAGNQHSG-PEGDWRVRPGIPVGGFAFEYQNTWYPDIDDTAAAVLAFLTQHDDE
STARASAARSETVRRAVLWIIGMQNSDGGWAAFDHENNHLF---LNPFSDMDSL-CDPSTPDVTGRVIECLGMLRGILLEYMLRTITLSIQKALPYLIAT
QEETGAWYGRWAVNYIYGTCLVLCGLQYFVNNPEAPGIMAKAARWLSTIQNSDGGWGESLLSYRERAGCG--ASTPSQTAWALMGLLSVPGVE--SRAVK
RGVEYLVRTQDDVAVWTERQFTSGFPNHFYISYTLYRVFFPITALGRFVQLANEE--
>tr|A6R9E5|A6R9E5_AJECN Terpene cyclase/mutase family member OS=Ajellomyces capsulatus (strain NAm1 / WU24) GN=HCAG_06936 PE=3 SV=1
---------------------------------------------------------------------------------------------VQKVLRL
AVGHSLDLQRTDGAWCGEVHSNATFTAQYVFLQQQLGLPLDPT---EIEGLSRWLFSQQNEDGSWGLGPGLGGDVSTTTETYLALKILGVSPEDP---RM
AAARSSIIKAGSLPATRMFTRVFLASFGLIPWSAVPPLPAELILLPTLFPVNIYNLSSWARATCVPLLLIRHHEPLHSL-PN----RDELWTKDIPRD--
-----------FCYTIFF--TSADHGLR----------F---LRNLSRRKIINWILDHEQSGEWAGYWPPQHIWALSLEYSLDH--PVLRRGIAAVKSFV
LHDV--MRAQVT-VSQVWDTALMSIALSDSAPS-TGIISPTQAIDWLMHHEVAS-HRGDWRVRPKLATGGFCFEEFNTLYPDVDDTAAVIMALIKSNP--
-----AHLISGCVRRAAQWILGMQNRDGGWGAFDWNNDKFF---LNPFSDMDSL-CDPSTPDVTGRIIECFGMMMAGRHGPLESRLRASSQLAIAYLLGC
QENNGSWWGRWGVNYLYGTSNVLCGLAYYYDRSGSVSAVDRASEWLKARQHSNGGWGEGPESYDSLAGCG--QPTASQSAWVTMALLNYLSPT--DEVIQ
RGISYLVRSQVKYATWPLERYTAGFPGHLYMEYDYYRHYFPIMALGRYVNKLSES--
>tr|G7XNU8|G7XNU8_ASPKW Terpene cyclase/mutase family member OS=Aspergillus kawachii (strain NBRC 4308) GN=AKAW_06610 PE=3 SV=1
---------------------------------------------------------------------------------------------VERTLKL
ANDYALGSIRSDGHWCGELRSNVTITAEYIFLRHALGLDLRA----DNAAYCNYILSQQNCDGSWGLAPEYPGDVSTTTEAFLALKLLGASPDMP---VM
QQARAFVLKAGGAEKVRVFTRIFLATFGLFPWDAVPQLPVELILLPSSCPINMYTLASWARGTIAPLLIICHHRPVYAL-PE-----DELWLNPTDKN--
-----------VPYGLAF--SVVDNLL-YY----LNGLR---LRSYARRKCLQWILEREPTGDWAGIFPPMHIYAFVLEYELDD--PPVRLGIQALENFA
WEDE--KRIQAC-VSPVWDTALMSIGLCDAMSP--DKHVLQQAITWIRNRQLLK-PCGDWRIRPKLAPGGFSFEYENSHYPDVDDTAAIILAQLKQDP--
-----QSVASDSVIAAATWILGMLNPDGGWAAFDVENDKLF---LNPFSDMDSL-CDTSCADITGRILEAFGLMMRRESPILSQCYGMHALGGSHTLHPH
KRPTEP-----------GSD---DGV--VIT-SMRLMHLAPALQWLKSKQNDDGGWGEPLLSYRTTQLQQ--QSTPSQTAWALMGLLAHLPLT--DPAIE
RGIRWLVCSQQPEASWPEAVYTGGFPNHFYLGYDYYRHYFPMMALGRYLQASRAH--
>tr|A7HHR1|A7HHR1_ANADF Squalene-hopene cyclase OS=Anaeromyxobacter sp. (strain Fw109-5) GN=Anae109_4079 PE=4 SV=1
---------------------------------------------------------------------------------------------AGRAAAA
ASQYLYR-TQQRDHWRAELESNVTVTAEYVLLRQALGLDLEE----RRDALVRYLCSRQKADGSFGIASTLPGDVSTTAEAYLALRLLGLDREDE---RL
RAAERFIRGAGGLARVRVFTRINLALFGLFPWEAVPTVPAELIFLPRWAPVNVYRLASWARSTMVPLFVLFHHRPVFAL-PG-----DHLWLGPGDKR--
-----------VPYRAFF--NAADAWL-RV----HDRLRLGRLRTEALRACEEWILAREASGDWAGIFPPMLVLALHVAHGLDA--APVRRGLEAIERFA
VSDR--FRIEAC-QSPVWDTILALIGLLDSGES-PTDPRLVAARRWIEGMQLTN-DWGDWKVDPRGEPGGWAFEYANSWYPDVDDTAAVIVGLLKHDP--
-----ASRAGETVRRAAAWVASMQNRDGGWAAFDVNNDRLF---LNPFSDMDSL-CDPSSPDVTGRVLEAFGML-D------APHLRAACRRGVAYLRRA
QEPEGSWYGRWGVNYVYGTSNVLNGLARQRVPA--DPMVARALGWLDSVQNADGGFGEGLESYADAMGRG--PSTASQTAWGVMGLLAYRAAD--DAAVR
RGIAWLVERQLADGSWEEEAFTGGFPRHFYLRYHLYRHYFPLMALGRFCAQGRG---
>tr|L7J8W5|L7J8W5_MAGOP Terpene cyclase/mutase family member OS=Magnaporthe oryzae (strain P131) GN=OOW_P131scaffold00602g35 PE=3 SV=1
---------------------------------------------------------------------------------------------SCQALDH
ATEFARDTLVNKEHWCGWVLSNVTVTAEWIFLQYILGLEMSNE---DRRGFLKHFTSSQRPDGSWSLATQTGGELSCTIEAYLALKILGVSPEED---YM
VRARDYVRSHGGAEKMRMLSRFHLAMFGLIPWAAVPQMPPELIFMPSWSLVNIYKFSSWARCNIVGLCMLRVHEPLYAL-PN----KDELWLDPYHKA--
-----------IPYTVLF--QLGDLFLW--------------LRRWAVSSSIQWTLDHEPSGDWGGIYPPMHILALMLEWSQDD--PVIQRGIGACQFLA
EDPA--KWMQPS-VSPVWDTFLMIRAVADAKTT-DADKLLVKPVDWVLAQQIDDDHIGDWRIRPDIPAGGFAFEYFNKWYPDVDDTAVGVVALMRHDP--
-----SLVNDDRILKAAAWTLGMQNRDFGWAAFDADNNAFY---LHPFSDMDSL-TDSSTPDVTGHVLEMLGLMYRLERLAFLSQSHGACDRGLGYLLGS
QEAFGGWYGRWGVNYIFGTSAALCALAYFADRKG-RGKMAAGADWLRSRQNPDGGWGELLESYDNLAGRG--RSTPSQTAWALQGLLELEDPR--GEVVE
AGVNWLLRHQVTSATWPEDDYTAGFPGHFYLKYELYCHYFPMMALARYRSCIQDG--
>tr|A1D8P8|A1D8P8_NEOFI Prenyltransferase and squalene oxidase repeat protein OS=Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 
---------------------------------------------------------------------------------------------TNQVLRL
ATQYSRVQRRPGGNWRGQTRINIATTAEHILMHQALGSLD--T---DRDAFISWFYSVQNSDGSWGINPG--GDLSVTVEAYLALRILGAPN-VH---QM
RRSQSFIIAEGSIAKVF-ITRIHLAMFGLYPWNAVRSQPPELMLL--LS--SICCWPAMDHTVLIPLLILCHHRPIFPL-PID----NELRCNPPKQEKA
---------FC---APAS--TSTDLVV-HF----LNLL-ILPLRRYALDRSVAFILQTRETGGVGHLSRPLHILALKLEYSVQSR--PLRTALDDIGHFV
YEDE-GKRILSV-NTTLRDSSRMITGLEDAGIA-VDAPWFRKSVQWLQRCLLPD-VNNDA-S-------TFE-----TRVCRVDDMASAIHAVIRQDPLM
----L---RSHLVANALQWLLKRQNADGGWTSLSCSNYL---------TSPDKH-VRQSTPDATGHVLETFGLLLTVSRGTLIDHVASASRRAIHYLSVT
QQPCGAWFGCCTRYHIYATSAVLRALAYFIGVKENNDDVSQAIHWLESLRNQDGGWGDICW-----REKGG-TSTASQTALTLLALLPYLS--PMNSILR
DGVEYLLRTQTKAATWTEDQSMTCSPACTYISSSYSSHYFAMMAIGRYAQSLRGY--
>tr|W4M923|W4M923_9DELT Uncharacterized protein (Fragment) OS=Candidatus Entotheonella sp. TSY2 GN=ETSY2_14705 PE=4 SV=1
---------------------------------------------------------------------------------------------LVQAIKR
SQGCLVSQQHADGYWVGELEANTTLTSEYILFRHLIGQVDR-D--R-EAKIVAYLLSEQLPDGGWALYYGGPSDLSTTIEAYVAMRLAGVAADAL---PL
RLARKRIHALGGLSHARVFTKIFLALFGQFEWRGIPVIPPEIISLPQSFYFNIYEFSSWSRSVIIPLTVIFAKKPLYHL-PPC---RDELFVEPPGARY-
----------S----LAF--VLLDGIL-KA----SEKY-SPVLRENALRQCEQWILEHDHTGDWGGIMPAMMVLALVFLYPLDS--GPVAKGLEAIERFG
IEEGSFR-LQSC-VSPVWDTVLSVTALADSGM--PTELPMRKALLWLLSKQVR--RDGDWSVNRRGEPGGWSFEFNNDFYPDNDDTAAVLIALHKAGLPD
----E--EKGDAMQLGLRWLLSMQCDDGGWGAFDVNNNKTL---INPFADLESL-LDPSTCDLTGRALELLGLIG-------FPRSHRIVERAVRFIRQN
QEPDGPWYGRWGVNYIYGTCHVLCGLHAVGENMR-QPYIRRAVQWLIDHQN-DGGWGESCRSYEEYRGVG--KSTASQTAWALMGLMAAGI--RH-SSVA
RGVTFLLRTQNAPGTWNEPEFTGGFPKYFFIKYHMYQHYFPLMALARYYSLTRDS--
>tr|A0A066YWR8|A0A066YWR8_9ACTO Squalene-hopene cyclase OS=Kitasatospora cheerisanensis KCTC 2395 GN=KCH_18050 PE=4 SV=1
---------------------------------------------------------------------------------------------PAAALSR
ATAHLLSLQHADGWWKGDLETNVTMDAEDLLLRQFLGIRTE-E--Q-TRATAAWIRSRQREDGTWATFHGGPPELSTTVEAYVALRLAGDAPDAP---HM
RAAAAHVREHGGIAATRVFTRIWLALFGWWPWAKLPELPPEVLFLPSWAPLNIYSFGQWARQTIVPLTVVSAHRPVRPA-PF-----TELHTDPAHYPDR
----------P----GLF--QRLDQLM-HR----YHRH-IKPVRRLALRQAAAWIVEREADGCWGGIQPPAVLIALRLLYRLDH--PVMKAGLAAFDSFT
VHTE-KRWMEAC-QSPVWDTCLAAIALRDAGL--PDHPALVRAGDWMLGEEVT--TRGDWSVRPRLDPGGWAFEFQNDTYPDVDDTAEVVLALRRIDHP-
----DRPRLAGAVERAVGWSLGMQSKDGAWGAFDADNTSRL---PNPFCDFGEV-IDPPSADVTAHMVEMLAETG-------RS-RDPRARRGLAWLLRH
QEPDGSWFGRWGTNYIYGTGSVVPALIAAGISPD-HPAVRRAVRWLTGRQN-DGGWGEDMRSYEDWAGRG--DSTASQTAWALMALLAAGE--DS-ETVE
RGIAWLTRTQRPDGSWDEPQFTGGFPWDFSINYHLYRLVFPVTALGRYVHDAPLG--
>tr|B3E4L3|B3E4L3_GEOLS Squalene-hopene cyclase OS=Geobacter lovleyi (strain ATCC BAA-1151 / DSM 17278 / SZ) GN=Glov_2233 PE=4 SV=1
---------------------------------------------------------------------------------------------LDKAVEL
TRDFFFREQLPDGYWWAELESNVTITAEYIMLFHFLGMVDK-D--K-ERKMANYLLRQQTEEGYWTVWHNGPGDLSTTIEAYFALKLAGYHADHI---AL
RKARDFILANGGILKSRVFTKTFLAMFGEFSWLGVPSMPIELMLLPDWAYLNVYEFSSWARATIIPMSVLMANRPVYKL-PPA---RQELYVRPPRTDY-
----------T----NFF--IGVDHLL-KI----YESS-IRPFKKRATEKVEQWILEHEKTGDWGGIQPAMLILALHCLYANDH--PAVAKGLEALANFT
IEDSSLV-LQSC-ISPVWDTALVLQAMQEASV--PDHPSLIKASQWLLDREVR--IKGDWKISPDLEPGGWAFEFQNDWYPDVDDSTAVMIAIKDIKVKN
----T-KARQDAIRRGIDWCLGMQSENGGWAAFDKDNTKHM---LNPFADLEAL-IDPPTADLTGRMLELMGNFG-------YTKDHPQAVSALEFLKNE
QEPEGPWFGRWGVNYIYGTWYVLIGLEAIGEDMN-SPYIKKSVNWIKSRQN-DGGWGEVCDSYWDLMGCG--PSTASQTSWALMALMAAGE--GC-QAVE
RGIQYLLATQNSDGTWDEEAFTGGFPKYFMIKYHIYRNCFPLTALGRYRRLTAGT--
>tr|S9TQ71|S9TQ71_PHAFV Squalene-hopene cyclase OS=Phaeospirillum fulvum MGU-K5 GN=K678_14754 PE=4 SV=1
---------------------------------------------------------------------------------------------LETAIRK
AGSWLLDRQQQDGHWVAPLQSNACMEAQWCLALWFLGLEDHP----LRPRLGQSLLETQRADGSWEVYYESAGDINTTVEAYAALRSLGFPDSDP---RL
AKARDWILSKGGLGKVRVFTRYWLALIGEWPWEQTPNLPPEVIWLPDWAPFSIYNFSQWARATMMPLAVLSARRPSRPL-PSN---RDALFPEGR-ER--
-----------FDYSRFF--RAADKAL-HR----LQDMGFAPWRDAAVRHTLEWILRHDADGGWGGIQPPWVLMALHVEYALDH--PVMAKGLDALNHPG
WRVDEASWIQAT-NSPVWDTMLTLIAFEDTGLAKAHPEATAKAAQWLLDRQIR--RPGDWSRLPNLKPGGWAFEYANTQYPDIDDTAEALIALAPFRHDP
D--WQARGIEEAIRLGVDWLIGMQSASGGWGAFDKDNNKQL---LTPFCDFGEA-LDPPSVDVTAHIVEALARLG-------LTAEHPALARALAYIRAE
QEADGPWFGRWGVNYIYGTCAVLPALAAIGAD--SQPYVGRACDWLVSRQQENGGWGESCASYMDQAGRG--PVTASQTAWALMALLAVNRPED-RAAIE
RGCRYLVEHQ-ENGTWPEPHFTAGFPGAFMLRYDLYRQYFPMMALGRAVRAGIGT--
>tr|B6AQN0|B6AQN0_9BACT Squalene-hopene cyclase OS=Leptospirillum sp. Group II '5-way CG' GN=CGL2_11068087 PE=4 SV=1
---------------------------------------------------------------------------------------------LQEKVRL
AAESLISRQGEEGYWVEPLEADITITSEYVLLQYLLGRERD-E--FFRR-AAPFILESQGEDGGWPLYNGGPAEISATVKAYLALKLLGYDADHP---AM
QRARALVLERGGAINVNVFTRITLALFGQYDWKGVPALPPEMILLPRWFPLSIYTVSYWSRTVIVPLLFIYHYKPLLEL-PPK---GQELFITPMSVRV-
----------H----NLF--FVLDRIL-QA----WNRH-PSFLRRKALKKAMEWMIPRKGEGGLGAIYPAMAVLALRLEYEMDH--PLVRRAIQSIDDLV
FDLGQQS-VQPC-HSPIWDTALALGALYEAGL--DGSPFVSRALDWFCRKEVR--TVGDWSVVPGVEAGGWAFQFENDYYPDIDDTSVVLMDFAKWVPEM
----G--AYRDVFRRAIEWTLSMQGTDGGWGAFDKDNDFLF---LNPFADHGAL-LDPSTSDVTGRVTELLGILG-------YDARTPVVRRALRFLRKE
QEENGSWYGRWGVNYIYGTWSVVSALKAVGEDMS-APYVQRAMQFLFSRQN-DGGWGESCYSYFRTAGEG--VSTASQTAWALIALIHGGH--RH-PAVS
KGIDFLLSRQQADGKWLEQEYTGGFPKVFYLRYNMYRDYFSLWALSLYRNVLLDG--
>tr|S0EVH8|S0EVH8_CHTCT Uncharacterized protein OS=Chthonomonas calidirosea (strain DSM 23976 / ICMP 18418 / T49) GN=CCALI_01615 PE=4 SV=1
---------------------------------------------------------------------------------------------IRQALRG
AIHYLRDRQQPDGHWVAELEGDTILESEYILLLQFLGKNDP-E--KFR-KLANYIRSKQHPEGYWAIYPGGPPEVSASVKAYFACKLAGFSESEP---FM
IRARRAILSLGGVTHCNTFTKLYLSIFGQYDWYGVPVIPPELILMPKWFYFNIYEMSSWSRAILVPLSVINALRPYRPI-PAA---TDELFVGGKSKRM-
----------R----NVF--LIVDKIL-KL----YHAS-IKPFRKLALQRCLQWLLERENSGGLGAIFPAMTIMAYKCMLPDDH--PAIQKELKELAAFE
IEEGTIR-LQPC-VSPVWDTAISLNALLDSGY--PESEEIRKAAEWLLSKQTR--KKGDWAVVRNVEPGGWYFENENEFYPDVDDTIMVLMALYKTYCHD
GRTEAPPEVREAMRKGLNWVFAMQNRDGGWASFDKDNNRIL---FQPYADHNAM-LDPSSADITARVLEMCSYYG-------IGKTDPRVKRAIAYLYKE
QEEDGSWFGRWGVNYLYGTWQVLRGLSRIGEDMR-SERIQRAVRWLHSVQN-DGGWGESCQSYEPPKATG--PSTPSQTAWALMGLFNAGD--SS-CAVQ
RGIEYLLKNQTDDGTWLEEWFTGGFPRVFYLRYHFYRHYFPLWALAQYHRFVTGE--
>tr|A0LJS0|A0LJS0_SYNFM Squalene-hopene cyclase OS=Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) GN=Sfum_1989 PE=4 SV=1
---------------------------------------------------------------------------------------------LDEGILR
AVDWLVCDQHPDGFWAGMLQSNSCMEAEWVLAMHFLGIDDDP----KYDGVIRAILGEQRADGSWGVFHKPNGDINTTVECYAALRASGLAPESA---PL
SSAREWILAGGGLANIRNFTKYWLALIGEWPWEGTPTIPPELIFFPPRMPLNIYHFASWARSTIVPLSILSARRPVRPL-PER---RDELFPQGR-SA--
-----------FDFRGFF--HVCDRIL-RL----YART-RAPFRETAIRVCLEWIIRRETDGAWSGIQPPWILLALHAEYGLDH--PILRAGLRAFDSHW
SYERG-IYLQAS-ESPVWDTVLSLRALADCGEERKASVSIASALEWLLNRQIS--VPGDWAVVPSVPCGGWAFQRANSFYPDVDDTAVAIEVLARLRPFT
---ANQSAVDRAIRSARDWVLAMQCSNGGWAAFDRDNDFKL---VTPFCDFGEL-LDPPSVDVTAHVIEALAALG-------WDMTSREIEAAVSFIRRE
QEAEGSWFGRWGVNHIYGTATVLPALRAIGED--SSAYVLRAADWLASRQNADGGWGETPASYMDLRGVG--ESTASQTAWAIMGLVAVGSGAH-DDTVR
RGIDFLLFA-QHGGTWEEPQYTGGFPGAFMINYNLYRHYFPLMALGRARYHLQLR--
>tr|H0TEF6|H0TEF6_9BRAD Squalene-hopene cyclase OS=Bradyrhizobium sp. STM 3843 GN=shc PE=4 SV=1
---------------------------------------------------------------------------------------------LHSTVRA
AADWLIAHQKGDGHWVGRAESNACMEAQWCLALWFMGLEDHP----LRPRMGQALLQTQRADGSWQIYFNPNGDINATVEAYAALRSLGHRDDEP---VL
QRARQWIEAKGGLRNVRVFTRYWLALLGEWPWEKVPNIPPEVIWFPVWFPFSIYNFAQWARATLMPIAILSARRPSRPL-PAN---RDALFPKGR-GA--
-----------FDYEKFF--RGADKVL-HA----LQNLGLGLWRPAAMSRVLEWMIRHDFDGAWGGIQPPWILMALYVEYPINH--PVVAKGLDALNDPG
WRVDEATYIQAT-NSPVWDTILTLLAFDDAGVIGDYPEAVEKAVNWVLARQVR--VPGDWSVLPHVKPGGWAFEYANNYYPDTDDTAVALIALAPLRHDP
K--WQAKGIDEAIQLGVDWLIGMQSQSGGWGAFDKDNNQQI---LTPFCDFGEA-LDPPSVDVTAHVIEAFGKLG-------LSRNHPTMVRALDYVRRE
QEPSGPWFGRWGVNYVYGTGAVLPALAAIGED--SQPYIQRACEWLVAQQQDNGGWGESCASYMDAVGRG--TATASQTAWALMALLAANRPGD-REAIE
RGCLWLIEHQ-SAGTWAEPEFTGGFPGAFMLRYGMYCHYFPLMALGRTLRPQAHG--
>tr|Q07I43|Q07I43_RHOP5 Squalene-hopene cyclase OS=Rhodopseudomonas palustris (strain BisA53) GN=RPE_4468 PE=4 SV=1
---------------------------------------------------------------------------------------------LRESVQQ
AADWLVANQKPDGHWVGRAETNATMEAQWCLALWFLGLEDHP----LRVRLGRALLDTQRPDGAWHVFYGPNGDINATVEAYAALRSLGHRDDEE---PL
RKARDWILSKGGLANIRVFTRYWLALIGEWPWEKTPNILPEVIWLPTWFPFSIYNFAQWARATLMPIAVLSAHRPSRPL-APD---RDALFPQGR-DS--
-----------FNYDVIF--RKIDTIL-HR----LQDWGHGIMRRGAIDHVLQWIIRHDYDGSWGGIQPPWILMALHTEYAMTH--PVMAKALDALNEPG
WRIDDATFIQAT-NSPVWDTMLSLLAFDDAGLGERYPEQVERAVRWVLKRQVL--VPGDWSVLPDVKPGGWAFEYANNFYPDTDDTSVALMALAPFRHDP
K--WQAEGIEDAIQRGIDWLVAMQCKEGGWGAFDKDNDKKI---LAPFCDFGEA-LDPPSADVTAHIIEAFAKVG-------LDRNHPSIVRALDYLKRE
QEPEGPWFGRWGVNYVYGTGAVLPALAAIGED--RQPYIARACDWLIARQQANGGWGESCVSYMDQAGEG--TATASQTAWALMALIAADRPQD-RDAIE
RGCLYLTETQ-RDGTWQEVHYTGGFPGSFMLRYDLYRHYFPMMAIGRVLRQRGDR--
>tr|E1YL66|E1YL66_9DELT Squalene--hopene cyclase OS=uncultured Desulfobacterium sp. GN=N47_E43610 PE=4 SV=1
---------------------------------------------------------------------------------------------LNRSIEQ
GLRWLDSHQKPQGFWMGILESNVCIESEWLLAMHFLEIKNDS----KVEGMVRGILNKQRSDGSWETYYDPGGDINATVEAYAALRATGIAVDAP---PL
EKARKWIFEHGGLPKIRVFTRYWLALIGEWPWSKTPNIPPEIIFFPRWFPFNIYNFASWVRTTLLPLSILCARCPVLPL-SDR---RDELFPEGR-SR--
-----------MNYSQCF--LMLDHFL-HT----YQKI-ITPGRETAIRLCLEWIIKHDADGSWGGIQPPWILIALHTEYPLDH--SILHKGLDTLNDHW
LYERG-LHIQAS-ESTVWDTSLALISMQDCRRDYRNSDTMQRAVEWLLDQQIR--EPGDWKVVKKAKAGGWAFERANRFYPDVDDTAVILLVLTRLAGVY
---KNREKLQEAIDCALNWLLAMQSSNGGWAAFDKNNNLAI---LTPFCDFGEA-LDPPSIDVTAHVLEACGYLC-------MDIHHPVVHRAVKFIRKE
QEPEGCWFGRWGVNYIYGTAAVLPALKAVGED--HASYVRKAADWIQTRQNSDGGWGETCRSYMDIRGMG--PSTPSQTAWALMGLLAVDSGCY-RGNID
RGLNFLIQR-QKSGSWHEPQYTGGFPGGFMIKYNLYCHYFPLIALGRARDHLSFE--
>tr|C5BPY1|C5BPY1_TERTT Squalene-hopene cyclase OS=Teredinibacter turnerae (strain ATCC 39867 / T7901) GN=shc PE=4 SV=1
---------------------------------------------------------------------------------------------ADSAVDR
ALFWLLDAQYEDGYWAGILESNACMEAEWLLCFHVLGIANHP----MSRGLVQGLLQRQRADGSWDVYYGRAGDINTTVEVYAALRCQGYAADHP---DI
KRARDWIQLQGGVKQVRVFTRFWLALIGEWPWEETPNLPPEILFFPRWFPFNIYHFAAWARATLVPLCILSARRMVVPL-NKS---CQELFPEDR-SA--
-----------VV--TFF--YHADRAL-KK----YQRTFRPPGRQQAIKMCLEWILRRDADGAWGGIQPPWILMALKAEYPVTH--PVMAKGLAALDAHW
SYERGARFVQAC-ESPVWDTLLSSFALLDCGFSCTSSSELRKAVDWILDQQVL--LPGDWQQLPTVSPGGWAFERANVHYPDVDDTAVALIVLAKVRPDY
---PDTARVNLAIERGLNWLFAMQCRNGGWGAFDKDNDKDL---LTPFSDFGET-IDPASVDVTAHVLEALGLLG-------YRTTHPAVAKALEFIRSE
QENDGCWFGRWGVNYIYGTAAVLPALASLNMN--NQEFIRRAANWILGKQNNDGGWGESCASYMDQRGRG--PSTASQTAWAMMSLLAVDGGTY-AESLL
RAEAYLKTTQTPEGTWDEPYYTGGFPGGFMINYNLYRHYFPLMALGRLAALRGA---
>tr|Q3A7M9|Q3A7M9_PELCD Squalene cyclase OS=Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1) GN=shc-1 PE=4 SV=1
---------------------------------------------------------------------------------------------LDDGIES
AIEWLAENQDKEGFWVGMLESNSCIEAEWILAMHLLGVKDDP----KYDKVVQAILNEQREDGSWAVYYDPAGDINATVEAYAALRTAGFGAGDE---RL
IKARNWIFSHGGLKNVRVFTRYWLALIGEWPWDETPALAPEIIYLPAWCPLNIYDFACWARATLVPLSVLSVRRPVKPL-PAS---RDELFPEGR-EN--
-----------ADYSRFF--LVVDWFL-KK----YNRL-MQFGREKAIRLCLEWIVRHDYDGGWGGIQPPLILIALNTEYGINH--PVISKGLDAFNPPW
AYEKG-VYLQCS-ESPVWDTLFTMLALFESGCSFDDTPMMRPALDWILSKQIT--SWGDWQVVRGVRPGGWAFERANTAYPDVDDTALALVVLAEARRHV
K--DS-AAVDAALERAEEWILGLQCRNGGWAAFDRDNNSAI---VTPFCDFGEV-LDPPSVDVTAHVVEALAALG-------RDRHDPVVARALKYIRSE
QEPGGSWFGRWGVNHIYGTCAVLPALAAIGED--RAPYVLRAADWLVRHQNDDGGWGESCASYMDQCGQG--SSTASQTGWALMALVAMSSHDY-DEAIR
RGLDYLLSH-QKSGTWDEPQYTGGFPGGFMINYNMYRHYFPLIAMARARRHLGLA--
>tr|C6HUP1|C6HUP1_9BACT Squalene-hopene cyclase OS=Leptospirillum ferrodiazotrophum GN=UBAL3_69480035 PE=4 SV=1
---------------------------------------------------------------------------------------------LSRTLAR
AVSWLVAAQDGAGHWVAPLEADATIPSEYVFLHEVLGRPLD-P--VRRDKIVRAILSVQGKEGAWPLFHDGDPDISATVKAYQALKLCGFDPSHP---AL
VRAREWVLSQGGAGKVNVFTRIALAIFGQYSWTKIPALPAEMVLLPSWFPFSIYSVSYWSRTVIVPLLFIYHHKPLVRL-SPR---GSELFDPARPDGE-
----------S----NLF--LLLDKVL-QV----WNRH-PGFLRKKALSFAMEWMVPRKGEGGLGAIYPAMAAVALSLEYELDH--PLMQRVLASIDDLL
IEGEEVL-VQPC-VSPVWDTALAMGALIEAGI--SDSPTVDRAMEWFCAREVR--TRGDWAIAPDCEPGGWAFQFENDYYPDVDDTAMVLMGMAKILPAR
P--DLAARMEGVFRRATLWVMAMQGTDGGWGAFDRDNDLLF---LNPFADHGAL-LDPSTADLTGRVLELLGALG-------YGPDFPPAARAIRYLRRE
QEEDGSWFGRWGVNYIYGTWSVVAGLKSIGVPMS-EPWVMRSMEFLLARQN-DGGWGEDCLSYASFAGRG--ASTPSQTAWALIALLHGGH--GH-MAVR
QGVDYLIQQMTPEGTWNEELFTGGFPRVFYLRYHMYRHYFPLWALALYRNMTERG--
>tr|V4L3Y9|V4L3Y9_9DELT Uncharacterized protein OS=uncultured Desulfofustis sp. PB-SRB1 GN=N839_09405 PE=4 SV=1
---------------------------------------------------------------------------------------------LNNAIEQ
AIAWLMGAQHQDGYWVGNLQSNSCMEAEWVLAMYILGVLADP----KYDGVVKAILHDQRADGSWEIYYDPAGDINATVESYAALRVAGVDKNSD---PM
IRAREWIFAHGGLGGVRVFTKYWLALIGEWPWDRTPALPPEIFFIPRWAPFNIYKFATWARATMLPLSILTARRPVHRL-PDL---RDELFPEGR-EH--
-----------FNYRGFF--LATDRIL-NR----YVNA-LRPGRETAIRLCREWIVAHDGDGAWGGIQPPWILMALHEEYALHH--PVLTSGLTAFDPPW
SYERR-IYLQPS-VSPIWDTVLVLLALLDCSVAHLQTVSVEKAVRYLLSQQVL--VGGDWQVVKDTEPGGWAFEYENDKYPDVDDTAVAVIVLLRLEPLM
ADEGLKRAMREAVEKAVAWLIAMQNDNGGWAAFDRDCTSAI---LTPFADFGEL-LDPPSVDVTGHVVEALALYG-------MTRDDEVMTRACRYMLDE
QEPDGSWFGRWGVNYIYGTGAVLPALEAAGVD--SAEKIVAAGRWLVSRQNLDGGWGESCASYMDFRGRG--VSTASQTGWALMALIALDSDEF-ARPIK
QGLEFLKKTQNQDGTWDEPYFTGGFPGGFMLNYNMYRHYFPLMAMGRARRYLTAG--
>tr|Q3A7E3|Q3A7E3_PELCD Squalene cyclase OS=Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1) GN=shc-2 PE=4 SV=1
---------------------------------------------------------------------------------------------LSASLKH
SREWLLSLQADAGNWVFALEADTTIASEYVMLQRFLGRLAP-E---LQQRLANYLLSRQLPDGGWPLYAE-GANISTTVKAYLALKLLGYPTHCD---PL
VRARQIVLALGGAEKCNVFTRIALALFGQIPWRTTPAMPVEIMLLPRWFYFHLSKISYWARTVVVPLLILYAKRPVCRL-EPE----PELFVTPPDLGYL
---------DV----NVF--IWVDRLT-RK----MVRC-PRRLHNLALRAAETWTREHQGAGGIGAIFPAMAVMALRTLCSPDD--ADYQRGLKALDDLL
DRCDDQGICQPC-ASPIWDTGLALTALLEGGL--D-HPAVDRAVRWLLDQQV-D-VKGDWAQVPNLEAGGWAFQFENALYPDLDDTSKVLMSLIRAGAM-
----DNPGYRQELSRAINWVIGMQNSDGGWGAFDVDNNYLY---LNPFADHGAL-LDPSTADVTGRCIEMLAMAGFG----R---DFLPIARGVDFLRRE
QEDFGGWYGRWGVNYIYGTWSALSGLIHAGEDLQ-APYIRQAVGWLESVQNPDGGWGETCYSY--LGR--G-VSTASQTAWALLGLMAAGE--D-NLAVR
RGIQYLVEEQNR-GGWDERHFTGGFPRVFYLRYHGYSQYFPLWALGLYERLSSGN--
>tr|Q6N3F4|Q6N3F4_RHOPA SqhC protein OS=Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009) GN=sqhC PE=4 SV=1
---------------------------------------------------------------------------------------------LEASIDA
ARSALLNYRRDDGHWVFELEADCTIPAEYVLLRHYLGEVDA-E---LEAKIAVYLRRIQGAHGGWPLVHD-GFDMSASVKGYFALKMIGDSIDAP---HM
VRAREAIRSRGGAIHSNVFTRFLLTLYGVTTWRAVPVLPVEIMLLPSWSPFTLTKISYWARTTMVPLLVLCALKPRAKN-PKV----DELFLQDPKIGMP
---------VK----KLF--GSIDAVL-RV----IEPV-PKSIRKRAIDKALAFIEERNGEDGMGAIFPPMAVMMYEALYPEDY--PPRASQRRGIDLLL
DRG-DEAYCQPC-VSPVWDTALASHAVLEADGH-E--KSVRPALDWLLPRQVLD-LKGDWAVAPNVRPGGWAFQYNNAHYPDLDDTAVVVMALDRARKDQ
----PNPAYDAAIARAREWIEGMQSDDGGWGAFDINNTEYY---LNPFSDHGAM-LDPPTEDVTARCVSMLAQLGET----M--DSSPALARALGYLRDT
QLAEGSWYGRWGMNYIYGTWSVLCALNAAGVPHA-DPMIRKAVAWLESVQNRDGGWGEDAVSYRL-GYESA-PSTASQTAWALLALMAAGE--D-HPAVA
RGIEYLKSTQTE-GLWDEQRYTAGFPRVFYLRYHGYSKFFPLWALARYRNLQATN--
>tr|A1AM25|A1AM25_PELPD Squalene-hopene cyclase OS=Pelobacter propionicus (strain DSM 2379) GN=Ppro_0765 PE=4 SV=1
---------------------------------------------------------------------------------------------LDSVTKS
AAALLASRQNPDGHWVFDLEADVTIPAEYVMMRCFIGELDS-D---MASRLSAYLLERQLPDGGWPLYAV-GANISATVKAYFALKLLGHDKYAP---HM
VSARRMILAQGGAERSNVFTRITLALFGQVPWHTTPAMPIEIMLLPKWFFFHLSKVAYWSRTVIVPLLILYNKQPVCRL-GYE----AELFSTSPDLVHL
---------DH----NAF--IVLDRLL-KR----TMHL-PGRIKRRALEEAERWTRERKGDGSIGAIYPAMAVMALKTLCGDSD--PDYLRGLRAIDRLL
HGKPAFSFCQPC-NSPVWDTALSLTALSEAGG--G--YSPERAMEWLFNRQI-A-TQGDWTECPGLECGGWAFQYENALYPDVDDTAKVLMSLFRAGAL-
----ERGEYPEKIAKAVRWVLGMQGADGGWGAFDVDNNHFY---LNPFADHGAL-LDPSTADLTGRCIEMLGMLGHG----P---DYPPITRGIEFLREE
QEPFGGWFGRWGVNYIYGTWSVLSGLSQAGEDMG-RPYVRKAVEWLVSCQNDDGGWGETCASY--LGS--G-ASTASQTAWALLGLMAAGE--D-HAAVR
AGIAYLADS--F-DGWDERHFTGGFPRVFYLRYHGYSLFFPVWALGVYARHREGG--
>tr|L0RFX3|L0RFX3_9DELT Squalene--hopene cyclase OS=Desulfovibrio hydrothermalis AM13 = DSM 14728 GN=shc PE=4 SV=1
---------------------------------------------------------------------------------------------PKDAMKR
VAKRFRSLQSPDGYWVFALEADVTIPSEYIMFNRFLERIDP-A---VAKRLGNYIRSKQMPDGGWPLHDE-GINISASVKAYMALKMLGDDKDAE---HM
VRARRTILAKGGAETSNVFTRICLATFGQIPWHCPPAMPIEIVLLPKWFFFHLDKVSYWSRSVIYPLLIIYAKQPVCKL-RLE----PELFCKPAEHIHI
---------DK----NAF--ILLDRIL-KR----TLHL-PDMIHNKAIKYAEKWTREHAGRGGIGAIFPAMAVTAMHLLYDESD--PDFARGLKAVDDLM
DKFQEQCMCQPC-NSPIWDTCLTLSAMMEAGE--D-SKLTQQSIKWLWDQQI-F-FKGDWKSAPKLEGGGWAFQFENTFYPDLDDTAMVLMAMARAGVL-
----ENKDNHENFVKGVNWLLGMQSSDGGYAAFDIDNCALY---LNPFADHGAL-LDPPTSDLTARVIELLGVIGYD----Q---NFKPIRQGIEFLKKE
QEEDGSWFGRWGVNYIYGTWSVLCGLRQVGEDMN-SPYICKAVEWFENHQNKDGGWGESCLSY--YGL--G-DSTPSQTSWALLGLMAAGK--N-SKAVS
RGIRYLLETQKE-GSWNEKHFTGGFPKVFYLRYHGYSQYFPMWALGVYDRFSAGE--
>tr|B9M4C2|B9M4C2_GEODF Squalene cyclase OS=Geobacter daltonii (strain DSM 22248 / JCM 15807 / FRC-32) GN=shc-2 PE=4 SV=1
---------------------------------------------------------------------------------------------LEKVTSV
AASQLAGQQQDDGHWVFDLEADVTIPAEYVMLQRFIGRIDP-E---ISERLAAYMQERQLPDGGWPLYAV-GVNISASVKAYFALKLLGHDKNAP---HM
VRARQLILSLGGAAKCNVFTRITLATFGQIPWHTAPAMPIEIMLLPRWFFFHLNKVAYWSRTVIVPLLILYATQPICRL-QYE----TELFTTPPDLVHL
---------DK----NVF--IALDRVL-KR----TMHL-PGRIKQHALAEAERWTRARQGDGGIGAIYPAMAVMALKTLCSDDD--ADYLRGLEAVDNLM
HRNLEFSFCQPC-NSPIWDTCMSLSALCESGY--ANSGVTDRAIKWLFSQQI-A-TPGDWSECPGLESGGWAFQYENSRYPDVDDTAKVLMSLFRAGAL-
----EKPEYREKIERAIRWVQGMQSTDGGWGAFDVDNDYFY---LNPFADHGAL-LDPSTADLTGRCIEMMGMLGHG----P---DYPPIARGIAYLKKE
QEPFGGWFGRWGVNYIYGTWSVLSGLHQAGENMD-APYVRKAVEWLISCQNSDGGWGETCASY--LGS--G-ASTASQTSWALMALMAAGE--R-HSAVR
NGVRYLTES--Y-NGWNEKQFTGGFPRVFYLRYHGYSLFFPVWALAVYSRYINGT--
>tr|Q029U6|Q029U6_SOLUE Squalene-hopene cyclase OS=Solibacter usitatus (strain Ellin6076) GN=Acid_1186 PE=4 SV=1
---------------------------------------------------------------------------------------------LAPAIQR
ACDALFSQQAADGFWCGELTADTTLESDYILLQLWLNQPDDHGWRPRIDRAGRSILERQLPDGGFNIYAGGPSEVSATIKAYCALKLAGLDPHSP---PL
RRARERILALGGLQAANSYVKINLSLFGLYPRKHVPSVPPEIVMLPGN---VLYEMSSWTRSILVPLSIVQARGSNRRA-PN-----DELLLPGVK----
-------------LAVLF--HHLDRM-FKV----WEKRGSERIRGAAIREAERWLIARHYTEGLGAIYPAMMIMALDALYAEDH--PDRSEAIRHFESLL
IETDDRFLFQPC-VSPVWDTAICAFALGEAG-NT-DDPRMTLAADWLISKEVR--RKGDWSIRPDTEPSGWAFEFANEFYPDIDDTAMVLLALMHANGS-
----NPEAQAAAERRAVNWLLAMQSSDGGWAAFDVDNNWAM---LNPFADHNAM-LDPTCPDITGRVLECLCRRGMA---GH-----DAARRGVAYLLQA
QEKDGSWYGRWGVNYIYGSFLAMRGLTTSGAP--SQDAVDRAARWLRAIQNPDGGWGESCASYARYVA-A--PSSASQTAWALLGLCAAGD--D-SAQFR
RGVEYLLTLQAPDGKWPEGATTGGFPNVFYLTYAMYRDYFPLLALSQV---------
>tr|Q029M2|Q029M2_SOLUE Squalene-hopene cyclase OS=Solibacter usitatus (strain Ellin6076) GN=Acid_1260 PE=4 SV=1
---------------------------------------------------------------------------------------------AELATRK
AMAYLTCLQERDGHWCAELTADTTLESDYILFQLWLYPPQDGKWRPLIRKAVNSILERQLPDGGFNICVGGPSEVSASVKAYVAMKLAGLPPEDD---RM
ARLRERILALGGIQAANSYVKVNLSLFDLYPREFSPSIPPEVALLPFD---LLYQMSAWTRAIVISLGIVHAANPRRPA-PA-----QELWLPGVS----
-------------PENTF--LTVDKA-LKL----WERYGSKAVRRRAVEKAKTWMIERHHSDGLGAIYPPMMVMALDVLYAKDD--PLRVEALRHFNNLM
VDDGDRFFFQPC-FSPVWDTAIGAYALVQAD-PS-H-EAIAPAADWLIAKEVR--RKGDWSVRPNTEPSGWAFEYSNEYYPDIDDTAMVMLALGETRAS-
----NTEAQAAACKRGLAWLLAMQSSDGGWAAFDADNNWEF---LSPFADHNAM-LDPTCADITGRVLEALASQGLDR--NH-----KAVRRGAEWLIRH
QENDGSWYGRWGVAYIYGTCFALRGLAASGEN--REAHILRAGEWLRSIQNADGGWGESCKSYDNFTG-G--PSTPSQTAWAILGLIAGGD--N-SLSVQ
HGIEYLLETQRSDGSWDEQFATGGFPRVFYLNYHMYKDYFPLLALASFVKARAGS--
>tr|Q1IQV9|Q1IQV9_KORVE Squalene cyclase OS=Koribacter versatilis (strain Ellin345) GN=Acid345_1740 PE=4 SV=1
---------------------------------------------------------------------------------------------IQQAMDA
AKRYLFSKQDPEGFWCGELEADTTLQSDYIVMHTLLGTGDP-V--KMQ-KAGKQILQHQNPDGGWNIYPDGPSNISAAVKAYFSLKLIGHKPDEP---EM
TKAREWILAHGGVTACNTFSKMYLCFFGQYDYDTVPAIPPEIVLFPNWFWFNLYEISSWSRGILVPLAICYAKKPFKKI-PDA---NDELFVEGRHANL-
----------H----NFF--LVLNNMV-HF----FERV-VRPLRKLAMKRAEKWMLEREMSDGLGGIYPAILIIALRALYSTDD--PQVIRAMDEFEKLG
IEEDTFR-MQPC-MSPVWDTAYALYALGEAGV--PSDPRMQKAAEWMLKKQVT--HKGDWAVVRNVQPGGWYFEFNNEFYPDVDDTAQVILSLNHVRTSN
---ER--YQDDTVKRALDWQLAMQCKNGGWASFDKDNNKMV---FQPFADHNAM-LDPATVDITGRVLEALSHHG-------YSLKDKVVQRAVKFIQSE
QEPDGSWFGRWGVNYIYGTMLCLRGLAAVGVDHH-EPMVQQAAEWLRMVQN-DGGWGESVGSYDDLRGQG--PSTASQTAWAVMGLLAAND--RS-DSVT
RGIAWLLENQKPNGSWWEKWITGGFPRVFYLKYTMYAEYFPLIAFAEYLRRLNTP--
>tr|E6PYY5|E6PYY5_9ZZZZ Squalene--hopene cyclase OS=mine drainage metagenome GN=shc PE=4 SV=1
---------------------------------------------------------------------------------------------VDAAVDR
SVEFLFGQQQPDGYWCGELEADAMLEADYIYMHVLLESGDPG----HMQRALTEMLRYQNEDGSWSIYPGGPGNISLAVKCYFACKLMGMSPDDP---IL
ARARSWILANGGVVACNTFTKMYLCALGQYDYDAVPAIPPEIVLAPNWFYFNIYEISSWSRAILVPLSIIYAKKPYKKI-PP-----DELFVGGRES---
------------DLRNFF--LLVDRA-FHV----VEAVYIRPLRKLAIRKAEQWMLDREMSDGLGAIYPAMMIIALRCLYSDDD--PQVIRARDEFEKLG
IEEEPTFRMQPC-MSPVWDTAYAVFALGEAGIPR-TDPRLLRAVDWMLAKEVR--HKGDWAEVRNTEPGGWYFEFNNEFYPDTDDTAQVLLALSRVENP-
----RERYQYEVSQRAIRWLFAMQCGNGGWASFDKDNTKMI---FQPFADHNAM-LDPPTVDITGRVLEMLSNYGYTR--SD-----KRVERAVQFLFRE
QEPDGSWFGRWGVNYIYGTFLVLRGLEAIGVE--NEPQIQQAAEWIRMVQNSDGGWGETCGSYDDTRGIG--PSTPSQTAWAILGLLAAGD--R-SDSVA
KGIRWLLDRQKESGDWDESVYTGGFPRVFYLAYHMYRNYFPLLALTTYKRAMQTI--
>tr|G8NZ37|G8NZ37_GRAMM Squalene/oxidosqualene cyclase OS=Granulicella mallensis (strain ATCC BAA-1857 / DSM 23137 / MP5ACTX8) GN=AciX8_1346 PE=4 SV=1
---------------------------------------------------------------------------------------------VIGGINR
SVEWLMGEQEEPGYWCGELEADSMLEADYIFMHTLLGSGDRG----KMERCINEILRHQNADGGWSLYPGGPSNVHYGVKCYLALKLMGWSADDP---VL
VRARENVLSLGGVVECNTFTKIYLCALGQYDYDAVPAVPPEMLLFPNWFYFNIYEISSWSRGILVPLSVIYSTKPFKKL-PP-----DELFVGGRAA---
------------DLHNFF--LMLDRM-MHW----AERIHIRPLRKIALKKAEKWMLDREMSDGLGAIYPAMMIIALRYLYSEDD--PQFIRAMDEFEKLG
IEEPARFRMQPC-MSPVWDTAYAVFALGEAGVPK-DDPRLLKAADWMLSKEVR--HKGDWAVVKNVEPGGWYFEFNNEFYPDVDDSAQVLLALNCVQNP-
----RERYQYEVSQRALNWIFAMQCKNGGWASFDKDNTKQI---FEPFADHNAM-IDPPTVDITGRILEMLSGYGFTR--SD-----KRVEKAVQFILKG
QEPDGSWFGRWGVNYLYGTFLVLRGLEAIGYS--LEPAVQQAAEWIRMVQNTDGGWGETCGTYDDQRGVG--PSTPSQTAWAILGLLAAND--R-SDSVA
KGIRWLIERQHEDGSWDELMYTGGFPRVFYLGYHLYKQYFPLLALTTYRKALERE--
>tr|C1F699|C1F699_ACIC5 Squalene-hopene cyclase OS=Acidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / JCM 7670 / NBRC 15755 / NCIMB 13165 / 161
---------------------------------------------------------------------------------------------VKRAIAG
AKDRVFAQQSKDGWWCGELEADSMLEADYIFAHTLLGTGDAG----KMKRALTEMLRYQNEDGSWSIYPGGPGNISLTVKCYFSAKLMGMTADNP---IL
VKAREWILAHGGVVECNTFTKIYLCFLGQYEYDAVPAIPPEIVLFPNWFYFNIYEISSWSRAILVPLSIAYAKKPFKKI-PP-----DELFVGGREA---
------------NLHNFF--LALDRV-THW----FERVHIRPLRSIALKKAEKWMLAREMSDGLGAIYPAMLIIALRCLYSLDD--PQVLRAMDEFEKLG
IDEPPTFRMQPC-VSPVWDTAQAVFALGEAGVPR-NDPRMQKAADWLLSKEVR--HKGDWAMVRNAQPGGWYFEFNNEFYPDVDDSAQVLLALNKVDNP-
----RERYQYDVCQRAIDWIFAMQCRNGGWASFDKDNTKMI---FQPFADHNAM-LDPPTVDITGRILEMLATYGYTR--KD-----RRVEKAIKFIYDE
QEPDGSWFGRWGVNYLYGTFLVLRGLEAIGVW--HEPQIQQAAEWIRSVQNADGGWGETCGSYDDTRGVG--PSTPSQTAWAILGLLSAGD--R-SDSVA
KGIKWLLAHQKPDGGWDESTYTGGFPRVFYLAYHQYRDYFPLLALTNYEKAMERG--
>tr|E8V785|E8V785_TERSS Squalene-hopene cyclase OS=Terriglobus saanensis (strain ATCC BAA-1853 / DSM 23119 / SP1PR4) GN=AciPR4_1994 PE=4 SV=1
---------------------------------------------------------------------------------------------IGKGIRS
SIDWLLGQQDAEGYWCGELEADVMLEADYIYVHTLLGTGDQG----KMRRAINEILRHQNEDGGWSLYPGGPSNINYGVKSYFALKLMGHSTEEP---YM
EKARNWILAHGGVVECNTFTKIYLCSLGQYDYDAVPAIPPEIVLFPNWFYFNIYEISSWSRGILVPLSIIYAKKPFKKL-PP-----DELFVGGREA---
------------NLHNFF--LFWDRL-MHW----AERVHIRPLRAKAIKAAEKWMLAREKTDGLGAIYPAMLIVALRCLYSVDD--PQFIRAMDEFEKLG
IDCPPTFRMQPC-FSPVWDTAQVLSTLGEAGISR-TDPLMIKAADWLLSKEVR--HKGDWAEVRNVEPGGWYFEFNNEFYPDVDDTGEVLLALKAVDNP-
----RERYQHDATERAINWIFAMQCKNGGWAAFDKDNTKSI---FQPFADHNAM-LDPPTVDITGRILEMLAAYGYTR--RD-----KRVESAIQFILRE
QETDGSWFGRWGVNYLYGTFLVLRGLEAMGMW--QETPILQATEWVRMVQNPDGGWGETCGTYDDQKGIG--PSTPSQTAWAVLALLAGGD--R-SDSVA
KGIRWLIERQHEDGSWDELVYTGGFPRVFYLGYHLYKQYFPLLALTTYKKAMEKE--
>tr|I3ZG94|I3ZG94_TERRK Squalene-hopene cyclase OS=Terriglobus roseus (strain DSM 18391 / NRRL B-41598 / KBS 63) GN=Terro_1976 PE=4 SV=1
---------------------------------------------------------------------------------------------VRAAVST
AKEWLLGQQHADGYWCGELEADVMLEADYIFLHTLLGTGDPG----KMQRAMNEILRHQNDDGGWSLYPGGPSNINYGVKAYHALKLMGWSQDDP---IL
VKAREWVLANGGVVECNTFTKIYLCAFGQYDYDAVPAIPPEIVLAPNWFYFNIYEISSWSRGILVPLSIMYAKKPLKLL-PA-----DELFVGGRAS---
------------DLHNFF--LFLDRM-VHW----AERIHIRPLRKVALKKAEEWMLEREGSDGLGAIYPAMLIVALRHLYSLDD--PQMIRAMDEFEKLG
IDCPPTFRMQPC-LSPVWDTAQVVSSLGEAGLSS-TDPRMIKAADWLLSKENR--HKGDWAQVKNVEPGGWAFFFNNIHYPDVDDTGEVLLALKMVDHP-
----QEARQHDAAERAINWVFGMQCRNGGWASFDRDNTKMI---FQPFADHNAM-LDPPTVDITGRILETLAAYGYTR--RD-----KRVEAAVQFILRE
QESDGSWFGRWGVNYLYGTFLVLRGLEAIGFD--NEPQVQQSVEWVRSVQNNDGGWGETCGTYDNSRGVG--PSTPSQTAWALLALLAGGD--R-SDSVA
KGVRWLVDHQAEDGSWSELVYTGGFPRVFYLGYHLYKQYFPLLALTTYDKCMSRS--
>tr|B9XSG0|B9XSG0_PEDPL Squalene-hopene cyclase OS=Pedosphaera parvula (strain Ellin514) GN=Cflav_PD0307 PE=4 SV=1
---------------------------------------------------------------------------------------------LETAIHR
SQSFLLKEQKPEGYWVGELIVDSTLVSDTIAYHHWNGKVDME----WQRKAVNHIFSMQLPDGGWNIYYGGPAEINATVKAYLALKLAGVPVMDP---RM
LRARSVALSMGGVPRMNTFSKLYLALLGLFPWNYVPTIPCEVILIGKWFHVNFYEMSSWSRSMLVPLAIINHFKPTRKL-QN-----DELYPEGYHR---
------------DLANFF--LWLDKLHKEL----WVQAGIHPFRRRALKKCEHWMLEREGSNGLAAIFPAMLLIALKALYPGDH--PEVKRAEKELKNLE
HETADTVRIEPC-FSPVWDTAIVAICLHESGIPS-DHPALKKSAEWLIDKEIR--FRGDWYFNPDVEPSGWVFEFENKWNPDVDDTAMVLLALRKIPTS-
----DVKRRDECFQRGLKWMMAFQCKDGGWAAFDKDCTKGI---LEPFADHNAM-LDPECADITARILELLGYEGVGV--DH-----PQIKKALQFIQEE
QEDDGSWYGRWGVNYIYGTWQVLRGLRALNIN--NQPWLLKARDWLESVQHEDGGWGERCNTYDDFKGQG--PSTASQTAWAVMGLCTFDD--Q-RPSLM
RGIDYLIKTQNSDGSWTEHEITGGFPRVFYLKYDMYRNSWPLLALATYRNLYASS--
>tr|B3DYT5|B3DYT5_METI4 Squalene-hopene cyclase OS=Methylacidiphilum infernorum (isolate V4) GN=sqhC PE=4 SV=1
---------------------------------------------------------------------------------------------VEETIKK
AQRYLLSIQKEDGHWVGELFVDVTLACDCIHLMHWRGKIDYK----KQLRLVKHIVDRQLPDGGWNIYPGGPSEVNATVKAYFALKLAGFSPDDP---LM
AKARSTILRLGGIPKCMTYTKLGLALLGVYPWDRLPVIPPEIILFPNWFPFNIYEISAWSRAMLVPLSVIHHFKPTRNL-PE-----HELFPYGTEG---
------------KFSGLF--LACDK--FQY----WDKTSLKPFRKMALKKAEKWLLERAGSDGLGAIFPAMHIMALIAMYTEDN--PILKKAIADFEGLE
VDDKDDLRIQPC-LSPVWDTAVGLVALAESGVAR-NAKELKRAAYWLLDREIK--IKGDWHVNPHPEPSGWAFEYNNVYYPDVDDTLMVLLALRLIDIE-
----DKIRKEEVMQRALRWVISFQCKNGGWAAFDKDVYKKW---LEPFADHNAI-LDPPCSDITARALELFGKMGIKK--TE-----RFVQKAIAYLKET
QENDGSWMGRWGVNYIYGTWQALRGLQAIGEN--NQEWILRARDWLESCQNEDGGWGETPASYDNLKGKG--PSTASQTAWAVSGIMACGD--F-RPSVS
RGIKYLCDRQLSDGSWAEEFLTGGFPGVFYLKYDMYRNAWPLLVIGEYHRQYLKA--
>tr|F0SK25|F0SK25_PLABD Squalene-hopene cyclase OS=Planctomyces brasiliensis (strain ATCC 49424 / DSM 5305 / JCM 21570 / NBRC 103401 / IFAM 1448) GN=Pl
---------------------------------------------------------------------------------------------LGKAISA
TTDFLLSRQHSEGYWVAELEGDTILESEYILLMTYLGEQDSE----DVQAAARYILEKQEDHGGWSLYPGGPTEISASVKSYWALKILGHDPSAE---YM
QRAKAAILAAGGAEKVNSFTRYYMALLGLISYRQCPAVPPELILLPSWTGVTIYEMSSWSRTILIPLSILWAFKPSRKL-PA-----DELFIKSPRLPVV
N-------DVSDKIDWLF--RQLDRG-YKL----IESIGEPPYRKMGIRLASTWMLDREQSDGLGAIFPPIVLVALRCLFEEDS--SQIKETRRHLDELI
LRGTPTVRLQPC-KSPVWDTAISTIALSETGQSN-CEAAIQRSAAWMRSKEVR--RKGDWSRHPDVEPGGWYFEFNNEFYPDIDDTTMVLMALARSLPTD
MHVSRLQNVLDSMRRGVQWLLAMQSKNGGWGAFDADNDNEL---LTPFADHNAM-IDPPTADITARVMESLAMLGIDR--NH-----PAMQEALAFVWKT
QEADGSWVGRWGVNYLYGTWQVLVGLNAIGID--TDPRIRQAVRWLKDTQLDIGGWGESPATYEDLKGKG--PATASQTAWALLGLMAAGE--G-SQAVQ
RGISYLLATQQEDGIWREEEFTGGFPRVFYLKYHYYPVYFPLMALARYRQLQRNG--
>tr|B4DCK3|B4DCK3_9BACT Squalene-hopene cyclase OS=Chthoniobacter flavus Ellin428 GN=CfE428DRAFT_6644 PE=4 SV=1
---------------------------------------------------------------------------------------------LDVAIRR
AQQNLLRLQHNEGYWCGELFVDSTLCSDYVLFMHWADEIDPV----MEEKCVAHIRRRQLEDGGWNIYEGGPSDVNATVKAYFALKLAGHAPTQP---WM
QEARACILRLGGIPKMNTYAKLYLALLGQFPWRYLPTVPVEIMFMPRWFFFDIYEVSSWSRAMLMPLAILNHYKPTKHL-PA-----HELYPIGSES---
------------DLGNFF--LFCDR--LKI----MHSLPWKPWKRAALARAEAWMTQREGSDGLAAIFPAMLMIALRTLYSREH--PLYVKAKNDFAGLF
VDDPQDFRIQPC-LSPVWDTAINLVALLESGLDP-HDPKIEAAVNWLKEKEVR--INGDWYVNHHVPPSGWAFEFNNVYYPDTDDTMMVLAALARAGAHE
E--SAPVETKAMFERALKWLLSFQCRDGGWAAFDKDVTQGW---LEPFADHNAI-LDPTCSDLTGRVLELLGLIDYDR--NC-----TPVRRALKFLRDT
QEDDGSWYGRWGVNYIYGTWQVLRGLRSIGED--RQQWIVRARDWLESCQNEDGGWGETCASYDDLKGKG--PSTASQTAWALMGLIAAADPGADRKSIR
QGVDYLLSTQVADGSWVEPEVTGGFPRVFYLRYDMYRNNFPLMALATYRKAREGK--
>tr|B9XL14|B9XL14_PEDPL Squalene-hopene cyclase OS=Pedosphaera parvula (strain Ellin514) GN=Cflav_PD2352 PE=4 SV=1
---------------------------------------------------------------------------------------------LNAAITR
SQSFLLCEQKPEGYWVGELMVDSTIVSDTIAYHHWNGKVDPE----WQRKAVNHILSMQLPEGGWNIYQNGPPEVNATIKAYLALKLAGIPITDP---RM
LKARQVALTLGGVPRMNTFSKLYLALLGLWPWKYVPTIPCEVLLLGKWFHVNIWDMSNWSRAMIVPLAIINHYKPTRPV-K------SELFLEGFHR---
------------DLANFF--LGLDQLHKEL----WVNAGIHPFRRLALKKCEQWMLEREGSDGLAAIFPAMLLIALKSLYPDDH--PEVLRAERELKKLE
HETKDTVRIEPC-LSPGWDTAIAAMCLRESGVPA-EHPRLKKAGDWLVNREVR--FKADWHHNPDVEPSGWVFQFNNKWNPDLDDTAMVLLALRLIPTD-
----HPRRRDEAFQRGLKWLLAFQCRDGGWAAYDKDCTKNI---LEPFADHNAM-LDPECADITARVLELLGFEGYAL--DH-----PQVQEAVEYLREH
QETDGSWYGRWGVNYIYGTWQTLRGLWALKMD--NQPWLLKARDWLESVQLPDGGWGERCNTYDDFKGQG--PSTASQTAWAVMALCTFGD--K-RPSLV
RGIQYLIENQNEDGSWTELETTGGFPRVYYLKYDIYRNTWPLLAMATYRKMLDPK--
>tr|I3IIW6|I3IIW6_9PLAN Squalene-hopene cyclase OS=planctomycete KSU-1 GN=KSU1_C0065 PE=4 SV=1
---------------------------------------------------------------------------------------------LDSAIQR
SQQYILRENKTDGHWVGILEADTTLTSDYIMLMHFLAKVDH-E--K-QKKAARLILDHQLPDGGWNIYYGGPSEISASVKAYFALKLAGYSANES---VM
QKARKCILDMGGIMRANCFTKIYLAMFGQVDWQAVPAVPAEMILFPPGFYFSIYEMSYWSRCIVVPLSIAIAKKPHIPV-DD----LSELYLIPRNVVY-
----------R----NFF--IDADSIF-RR----YEQQ-IKFIRQIALKKAEKWMLDHDNSGGLGAIWPGIIIFAMKCLYPEDH--PALLSQLKEVENLI
IYETRLY-LQPC-VSPVWDTAWAIIALHESGI--PTHPSLQKAGRWLLSKEVR--NFGDWTLCKVEEPSGWYFQYANEFYPDTDDSAAVLMALQRVSLPE
----S-AHKERTFLRGLKWLQAMQCDDGGWGAFDRNNNKAI---LNPFADFNAL-LDPSTSDVTGRCLEFLGRVG-------FSNTYTNIRSAIEFLQKE
QEKDGSWFGRWGANYIYGTWSVLSGLSTAGEDMD-KPYIKKAVEWLRKSQN-DGGWGETIKSYDDLKAIG--KSTPSQTAWALLAFFAVNE--KS-DAVE
RGIKFLLNGQKEDGSWDETEFTAGFPKVFYLKYHMYRNYFPLLALSRYRNLIQKL--
>tr|E8R5V6|E8R5V6_ISOPI Squalene-hopene cyclase OS=Isosphaera pallida (strain ATCC 43644 / DSM 9630 / IS1B) GN=Isop_2285 PE=4 SV=1
---------------------------------------------------------------------------------------------SALAARR
AAAWLLAQRKTDGHWVGELEGDTILETEWVLLKAFLGELDDP----EVVAACRSVRRDARPEGGWAIHPGGPFEISASVKAYFALKLVGVSPDEP---DM
VRARELILQHGGLDACNSFTRFYLALLGQIPYDDCPAVPPELVWLPSWVPFGLAAMSSWTRTLVVPLAILSSLKPCRPV-PD-----DELKN--P---H-
-----------FVPDGFF--LGVDRL-LKA----FDRIKPGVWRRAAVRSCHQWMLDHEDSDGLGAIFPPMIVVVLETLYDRND--RLFEWAVRQLDDLK
VRDEGLLWLQPC-LSPVWDTAIATIALADVRDAQALETALTTASRWLVAREIR--RKGDWAIFRHIEPSGWAFEYLNDHYADIDDTAMVLMALDRAGLR-
----DDPTVKPAIERALNWLLALQGRDGAWAAFDADIDNQV---LTPFADHNAM-LDPGCADITARVVEMLGQLGFAS--SH-----PSIQRALEFIWSR
QEPEGWWEGRWGVNAIYGTWQVLQGLAALGWP--SDPRLVKAADWLETIQQADGGFGESCRSYEDWIGQG--PPTPSQTAWGLLGLIAAGR--D-SPAAH
RAAAWLRDRQTSHGDWPEDQFTGGFPKVFYLKYHLYRVSFPIMALARHARALTRR--
>tr|A0A0C9Q1I8|A0A0C9Q1I8_9BACT Candidatus Brocadia sinica JPN1 DNA, contig: brosiA OS=Candidatus Brocadia sinica JPN1 GN=BROSI_A2108 PE=4 SV=1
---------------------------------------------------------------------------------------------LDITIYR
AQQYLLRNNRSDGHWVGILEADTTITSEYIMLMHFLGKVNQ-E--K-QRLAANLLCEHQISDGGWNIYYGGPSEISASVKAYFALKLAGYSANEP---FM
QKARKRILEMGGIMKANCFTKIYLAMFGQVDWQAVPAVPAEMILFPPGFYFSIYEMSYWSRCIVVPLSIAIAKKPHIPV-GD----MKELYLIPREVVY-
----------R----NFF--IDADSIF-RR----YEQQ-IKFIRRMALRKAEKWMLDHEKSGGLGAIWPAMVIFAMKCLYPDDH--PALKSQLQEVENLV
VYEVKLY-LQPC-VSPVWDTAWAIIALHDSGI--PSDPALQKAGRWLISKEVR--NFGDWALCKVEEPSGWYFQYANEFYPDTDDSAAVLMALQRVSLPE
----T-AHKEASVLRGLRWIMAMQCDDGGWGAFDRNNNRAI---LNPFADFNAL-LDPSTSDVTARCTEFLGRIG-------FSKTSGQIRMAIEFLKKE
QEKDGTWFGRWGANYIYGTWSVLAGLAAVGEDMN-KPYIKKAVAWLKSVQN-DGGWGETIKSYDDLKAIG--KSTPSQTAWALLGLMAAGE--HS-DAVE
RGIKFLLMKQKEDGSWDEVEFTAGFPKVFYLKYHMYRNYFPLMALGRYRNSIHNK--
>tr|M5Q358|M5Q358_DESAF Squalene-hopene cyclase OS=Desulfovibrio africanus PCS GN=PCS_00083 PE=4 SV=1
---------------------------------------------------------------------------------------------LDTAVGT
ALSRLLGLQSEQGYWVFDLEADATIPSEYVMLQRFLGRMRP-E---LKDKIARYLRNRQLPDGGWPLYTE-GADLSCTVKAYFALKLLGDAPDAS---HM
ARARQRVLEMGGAEKVNVFTRIALAIFGQVPWRTAPCMPIEITMLPDWFFFHLRKVSYWSRTVVVPLLILYARRPVAHI-APQ----RELFLQNPELRNL
---------DG----NLF--ILLDRIL-KC----TEGC-PVGIREEAVRRAERWTVERRGEGGIGAIFPAMAVMALRVLYPDSQ--PDMARGIKALDDLL
EKE-HEAFCQPC-VSPIWDSCLSLSASLEAGA--S-SPAMKACVDWLFSKQV-F-AWGDWAQSPDLQAGAWAFQFENDFYPDVDDTSMVLMALLRAGAL-
----DDPRYQERIGAAVNWTLGLQSSDGGWAAFDVDNNKLH---LNPFADHGAL-LDPSTADLTGRCLEFLGMLGFD----R---SFEPAARGLEFLRKE
QEADGSWYGRWGVNYIYGTWSVLMGLRQIGEDMR-APYVRRAVDWLLSRQNGDGGWGESCYSY--LGR--G-RSTPSQTAWALLGLMAAGE--H-SRAVR
RGIEYLVSNQLP-GNWDERLFTGGFPRVFYLLYHGYSQYFPLWALGVYRRLSKGG--
>tr|E8WXM9|E8WXM9_GRATM Squalene-hopene cyclase OS=Granulicella tundricola (strain ATCC BAA-1859 / DSM 23138 / MP5ACTX9) GN=AciX9_1592 PE=4 SV=1
---------------------------------------------------------------------------------------------IANGIKR
SAEWLLGLQHPDGYWCGELEADSMLESDYIFVHTLLGTGDPG----RLSRALNEILRHQNDDGGWSLYPGGPSNVNYGVKAYLALKLMGYTADHP---VM
VKARECVLRLGGVVECNTFTKIYLCGLGQYDYDAVPAVPPEIVLFPDWFYFNIYEISAWSRAILVPLSIIYAKKPFKKL-TP-----DELFVGGRAA---
------------NLRNVF--LFLDRV-AHL----AERVHIRPLRSIALKKAERWMLDHERSDGLGAIYPAMLIVALRCLYSADD--PQVIRAMDEFERLG
IDCPPTFRMQPC-FSPVWDTAQVLSTLGDCGLPR-NDERLVKAADWLLSKEIR--YKGDWSHVKNVDASCWCFFFNNDHQPDVDDTGEVLLALKAVDNP-
----RERYQHETAQRAIEWVFAMQCKNGGWASFDKDNTKKI---FEPFADHNAM-IDPPSVDITGRILEMLAGYGYTR--RD-----PRIEKAVQFILRE
QEPDGCWFGRWGVNYLYGTFLVLRGLQSMEYD--YEPAVQQAAEWIRMVQNSDGGWGETCGTYDNLKGTG--PSTPSQTAWALLGLLAAND--R-SDSVA
KGVRWLIDRQHEDGSWDELAYTGGFPTVFYLGYHLYKQYFPLLALTTYKQAMERE--
>tr|A0A0B0EPR3|A0A0B0EPR3_9BACT Squalene-hopene cyclase OS=Candidatus Scalindua brodae GN=SCABRO_01052 PE=4 SV=1
---------------------------------------------------------------------------------------------LNLAIKK
SQSHLLSEQEEEGYWAGILEGDVALTAEYLMLMHFLKRIDT-R--K-QEKAIRYIIKKQEKDGGWSIYHDGFSDVSISVKCYFALKLAGHSDDMP---YM
QKARSRILKLGGIMKCNTFTKIYLAIFGQFDWKGIPALPVEIIHLPKFFYFNIYEMSYWSRCIIVPLGIIMAKRPSSLI-GDA---VDNLYVIPRKVSY-
----------R----NMF--INFDTLL-RR----YENQ-IYSLRKMAIEKSEKWMLEREKSGGLGAIWPSMVLMAMRCLYKDGN--PIVEKAIEDIEALA
VHDETMF-LQPC-VSPVWDTPWAIMALLKSGL--PDDPALIKAGEWMLQKEVK--SFGDWSMNPVREPSGWYFQHANEFYPDNDDAAVVMMSLQLLDLPD
----K-DRKKQAILRGFKWLMGMQCNDGGWGSFDKNNNKKI---LNPFADWNAL-LDPSTSDLTARVLDLMGKLG-------YDLSFPPAKKAIEFLKKE
QEKNGSWFGRWGTNYVYGTWSVLTGLFSIKEDMT-KDYVRKATSWLKDFQN-DGGWGETCKSYWDLSAIG--RSTASQTSWAVLGLLCTEE--DS-EAVK
NGIEYLLKTQKEDGTWDEEEFTGGFPKIFYLRYHMYRSYFPLLALSKYRNMIK----
>tr|D2QYV8|D2QYV8_PIRSD Squalene-hopene cyclase OS=Pirellula staleyi (strain ATCC 27377 / DSM 6068 / ICPB 4128) GN=Psta_1738 PE=4 SV=1
---------------------------------------------------------------------------------------------LDVAILR
TSQWLKERQHADGYWCAELEGDTILESEYILLLAWLGKENST----IARKCAAYLVEQQLPAGGWAMYPGGKLEISGSVKAYFALKITGHDPQAE---YM
QRAVRAIRAAGGADAVNSFTRFYLALLGQISYDNCPAVPPELVLLPEWFPINLSKMSAWSRTIVVPLAIMWAHRPARKL-PD-----KELMLEHPEWKQT
---------KC--PGRFF--QTCDAT-IKG----LEQRKWRPLRRRALEAASSWMRTRAHSDGLGAIFPPIVIVALKCLYSDHS--AELIYNFDQLKGLT
IEEETTARLQPC-LSPVWDTAITLRSLAAAGMAV-DAPEASSAMRWLLSKEVT--RKGDWASNCDSPPGGWFFEHHNEFYPDIDDSVMVLIAMQEMASLS
GCSPRWRWMRSAGERALRWVLAMQNRDGGWGAFDKDNDSEF---LCPFADHNAM-IDPSTPDLTGRVLEALAMWNIPQ--SH-----PAVQRAILYCRKT
QLADGSWFGRWGVNYIYGTWQTLVGLAGIGVP--TEPIIQRGANWLLAHQQASGAWGESCDTYEDLAGQG--NPTASQTAWAILGLLAAGL--D-HPAVA
RGVNWLVQQQQPDGSWLENEFTGGFPRVFYLKYHYYPIYFPLLALGQYRAAKSRG--
>tr|A3ZNQ7|A3ZNQ7_9PLAN Squalene-hopene cyclase OS=Blastopirellula marina DSM 3645 GN=DSM3645_17425 PE=4 SV=1
---------------------------------------------------------------------------------------------ARAAVAS
TCDWLLSHQHADGHWCAELEGDSILQSEYILLLAWLGKERTE----IARRCAAHLLKQQEPNGAWTQFPGAPIDVGSSVKAYFALKLTGHDAAAD---YM
VRARNAILEAGGADKVNSFTRFYLALLGQIPFELCPAVPPEMVLLPNWSPINIYRISSWSRTIFVPLSIVWAHRAARDI-VE-----HELFIRKPEWPEL
---------RC--PGRFF--RTADSG-LKL----LEKYGLRPLRKRALRQAQQWMLDRQQSDGPGAIFPPIVAIALRTLYAEDS--PEIQYCLDHLERLV
LEDGETTKLQPC-KSPVWDTSITLRALAAAGLGL-AQEPTCRGVEWLLSKEVR--VPGDWTNNVDCEPGGWFFEYENAFYPDNDDTSMGIMALADQLAAA
NIAAMMEQAAAATRRAVAWMVAMQNKDGGWGAFDKNNDAEF---LCPFADHNAM-IDPSTPDLSARVIESFGRLGVTI--ESPGKLGDTVRRAVAYIRAN
QLSDGSWFGRWGVNYIYGTWQCLVGLRAVGVP--NDPAIEQGKLWLLAHQQACGGWGESCETYEDLRGQG--SPTASQTAWALLGIIAAGG--N-LAEVV
HGVQYLMDTQREDGAWDEIEFTGGFPRVFYLKYHYYPIYFPLLALAEWNRATARS--
>tr|M1YX70|M1YX70_NITG3 Squalene-hopene cyclase OS=Nitrospina gracilis (strain 3/211) GN=shc PE=4 SV=1
---------------------------------------------------------------------------------------------LDTAIAR
SCQHHFSTQYPEGYWVEELESNVTITAEYVFLMHFLGLDQP-E--R-KERIKNYLLAQQQEHGGWTLYYGGPPDIGTTVEAYVALKMCGLPLDAP---EM
AKARQCIFSLGGVRKARVFTKIFLAMLGQIDWKWTPATPVEAVLLPTWFYFNIYEMSSWSRGTVVPLSVVCSMKPVWPL-PTQ---SPEIFTGADR--M-
----------G----SAF--MLADRVL-KL----LGKS-WKPFRKIAMRRAEKWILKHEPEGDFSGIQPAMFVLALNLMYPMDH--PAIVKGMESIDRFF
IRQGQEW-MQAC-VSPLWDTAISCNALMDAGV--PDDPRIVKAIEWMMKKQVT--RGGDWQINPHTPPGGWAFEFYNEAYPDTDDTAEILMSIHRTAISD
----T-EWKEREFQRALTWLMSMQSSNGGWGAFDRDNDHEL---FNPFADHGAM-LDPPTVDVTGRILWMLGRIG-------HDPKDPRVEHALTFIRDS
QEREGCWFGRWGVNYIYGTWLVLMGLSSIGEDMQ-SSMVRRAVDWLNSRQN-DGGWGETCYSYSDYAGKG--DSTKSQTAWALMALVEAGE--QS-EVVR
RGVNYLITTQQDDGSWYEDEFTGGFPEHFYIRYHMYRQFFPLMALARYRHVLDHG--
>tr|D5SYK6|D5SYK6_PLAL2 Squalene-hopene cyclase OS=Planctomyces limnophilus (strain ATCC 43296 / DSM 3776 / IFAM 1008 / 290) GN=Plim_1904 PE=4 SV=1
---------------------------------------------------------------------------------------------LQTAIAR
TRQYLLDQQHSEGFFVAELEGDTILESEYILLLAFLNEGQSP----DAQAAARYLLTKQNTDGSWSNFPGGPIDVSCAVKAYLALRITGHAADEP---AL
IRAREAILQAGGVERVNSFTRFYLAMLGLIPYSLCPAVPPEVVLLPDWFPINLSQMSAWSRTIVVPLSLLWAFQPAVEL-NDD---GEELYASPEKLPRF
---------IRGVNHRFF--FRVDQC-LKS----IESYGIKPLRSRAVRKCVQWILDREMSDGLGAIFPPIVLIGLKCAFDDQH--PMVQKQRDELNRLM
LREQDALRLQPC-LSPVWDTAISIIALRESGVEP-DHPALSKARNWLLSKEVR--HAGDWSKHPETPVSGWYFEFNNEFYPDVDDTAMVLIALASTLPEE
ATLENHRPVLEAMGRGVQWLKALQSKDGGWGAFDSDINKEL---LTPFADHNAM-LDETNADISARVLEAYAAVGISF--ND-----PSVQRALEFIWND
QEDDHAWYGRWGVNYIYGTWQVLVGLTAIGIS--HDPRLVRAAGWLKSKQQACGGWGETPATYDNLRGQG--TPTASQTAWAVLGLIAAGE--N-SIECQ
RGVEFLLKTQKHNGTWDEEEFTGGFPRVFYLRYHYYPLYFPLMALGRFARAGGRV--
>tr|I0IQ92|I0IQ92_LEPFC Putative squalenehopene cyclase OS=Leptospirillum ferrooxidans (strain C2-3) GN=LFE_1762 PE=4 SV=1
---------------------------------------------------------------------------------------------LEEAIAN
ATRSLLDRQHPDGYWVEPLDADVTIPAEYVMFQFILGRKDE-V--FFRE-VAEYILSIQGADGGWPLFTGGTADISASVKAYFALKLLGYSPDHP---AL
VKARALILERGGATTVNVFTRIILALFAQYDWKGIPALPCEMILLPKWFPLSIYTISYWSRTVIIPLLIIYHYKPVTPI-PHQ---GDELFLKPMEVHF-
----------G----NLF--FVLDYFI-QH----WNRH-PSFLRKKALSKAVEWLIPRKGEGGLGAIYPAMAVIALRLSYSDDH--PLVKRAIASIDDLV
FSRDMQS-VQPC-HSPIWDTALSLGALFEAGV--SDHPAISRSLEWFRRKEVK--TVGDWAVVKGVEPGGWAFEFENDYYPDVDDTAVILMDFAKWTNGF
----K--GYEDVVRRAARWVLAMQCTDGGWASFDKDNDLLF---LNPFADHGAL-LDPSTADLTGRVLEFLGLYG-------YRPDFPPVARALDYLRRE
QEADGSWYGRWGVNYIYGTWSVISAFRALGVDMK-SSMVQRAMSFLLDHQN-DGGWGESCLSYSKTAGVG--ESTPSQTAWALIALIHGEH--DH-PQVR
KGISWLLENMRPDGRWNETLYTGGFARVFYLRYNMYRDYFPLWALALYQNVHFEG--
>tr|C6BRH5|C6BRH5_DESAD Squalene-hopene cyclase OS=Desulfovibrio salexigens (strain ATCC 14822 / DSM 2638 / NCIB 8403 / VKM B-1763) GN=Desal_1353 PE=4 
---------------------------------------------------------------------------------------------PTDALNR
VMKRFRSLQSPEGYWVFALEADVTIPSEYIMFNRFLGRMDK-G---LAERLGNYIRAKQMADGGWPLHDN-GVNISASVKAYMALKMLGDNKDAE---HM
VRARQIILAKGGAETANVFTRICLATFGQIPWHCPPAMPIEIVLLPKWFFFHLDKVSYWSRSVIYPLLIIYAKQPVCRL-RPE----PELFCKPAEHIHI
---------DK----NLF--ILLDRVL-KR----TIHL-PKSINKKALNYAEKWTREHAGRGGIGAIFPAMAVMALSLLYDESD--PDFARGMQSVDDLM
DKFHEQAMCQPC-NSPIWDTCLTLSAMMEAGE--N-SKSTQQALNWLWDQQI-F-FRGDWISAPKLEGGGWAFQFENTFYPDLDDTAMVLMAMCRAGVL-
----DQPEHRENFIKGVNWLIGMQSSNGGWAAFDIDNCAEY---LNPFADHGAL-LDPPTSDLTARVIELLGVLGYD----K---SFRPIKDGIEFLKKE
QEDDGSWFGRWGVNYIYGTWSVLCGLRQAGEDMN-SSYVCKAVEWFENHQNKDGGWGESCLSY--YGL--G-DSTASQTAWALLGLMAAGR--H-SKAVS
RGVRYLLDTQKD-GSWDESLFTGGFPRVFYLRYHGYSQYFPMWALGVYQRFSADE--
>tr|G6XHN3|G6XHN3_9PROT Squalene-hopene cyclase OS=Gluconobacter morbifer G707 GN=GMO_09990 PE=4 SV=1
---------------------------------------------------------------------------------------------LPEAVSS
ACDWLIDQQKPDGHWVGPVESNACMEAQWCLALWFLGQEDHP----LRPRLAQALLEMQREDGSWGIYVGDHGDINTTVEAYAALRSMGYAADMP---IM
AKSAAWIQQKGGLRNVRVFTRYWLALIGEWPWDKTPNLPPEIIWLPDNFIFSIYNFAQWARATMMPLTILSARRPSRPL-LPN---RDGLFPEGR-EN--
-----------FDYERFF--RAADKGL-HS----LQSFPRFVPREAAIRHVIEWIIRHDADGGWGGIQPPWILMALSVEYPLHH--PVLAKAMDALNDPG
WRRDDASWIQAT-NSPVWDTMLAVLALHDAGAEDRYSPQMDKAIGWLLDRQVR--VKGDWSILPDTEPGGWAFEYANDKYPDTDDTAVALIALAGCRHRP
E--WRERDIEGAISRGVNWLLAMQSSSGGWGAFDKDNNRSI---LTPFCDFGEA-LDPPSVDVTAHVLEAFGLLG-------ISRNHPSVQKALAYIRSE
QERNGAWFGRWGVNYVYGTGAVLPALAAIGED--TQPYIVRACDWLMSVQQENGGWGESCASYMDAVGHG--VATASQTAWALIGLLAAKRPKD-REAIA
RGCQFLIERQ-EDGSWTEEEYTGGFPGAFMLRYDLYRQYFPVMALSRARRMMKED--
>tr|A0A0D6PW87|A0A0D6PW87_KOMEU Squalene--hopene cyclase OS=Komagataeibacter europaeus NBRC 3261 GN=Geu3261_0005_009 PE=4 SV=1
---------------------------------------------------------------------------------------------LSHAISS
ACDWLIGQQKPDGHWVGPVASNASMEAEWCLALWFLGLEDHP----LRPRLGKALLEMQREDGSWGTYYGGNGDINATVESYAALRSLGYPADDP---AI
SRAATWIASKGGLKNIRVFTRYWLALIGEWPWEKTPNLPPEVIWFPNNFVFSIYNFAQWARATLVPLAILSARRPARPL-RPD---RDALFPGGR-AN--
-----------FDYERFF--RTTDRGL-HW----LQSRFRSTLREAAIRHMLEWIIRHDADGGWGGIQPPWVLMALHGEYQFHH--PVMAKALSALNDPG
WRHDDASWIQAT-NSPVWDTMLAIMALHDADGETRFTPEMEKALGWLLDRQVC--VKGDWSILPDVEPGGWAFEYANDRYPDTDDTAVALIALSSCRNRE
E--WKKRGVEEAISRGVNWLIGMQSECGGWGAFDKDNNRSI---LSPFCDFGEA-LDPPSVDVTAHVLEAFGILG-------LPRHMPTIQRALAYIRAE
QEPDGPWFGRWGVNYLYGTGAVLPALAAIGED--TQPYITKACDWLVAHQQENGGWGESCASYMEMVGRG--VTTPSQTAWALMGLIAANRPQD-YGAIA
RGCRYLIDLQQPDGSWDEKEFTGGFPGAFMLRYDLYRQFFPIMALSRASRLMKLE--
>tr|A0A087PTX1|A0A087PTX1_9PROT Squalene--hopene cyclase OS=Acetobacter malorum GN=AmDm5_0772 PE=4 SV=1
---------------------------------------------------------------------------------------------LTHTVSS
ACEWLISQQKPDGHWVGPVGSNASMEAEWCLALWFLGLDDHP----LRPRLGNALLQTQRDDGSWGIYLGGNGDINATVEAYAALRSLGYPEDHP---AL
HKASAWIAQKGGLRNIRVFTRYWLALIGEWPWEKTPNLPPEIIWFPNKFVFSIYNFAQWARATLVPLAVISARRPSRPL-RPD---RNALFPEGR-AN--
-----------FDYTDFF--RTTDKGL-HW----LQSKFRNTLREAAIRHMLEWIIRHDADGGWGGIQPPWVLMALHGEFQFHH--PVMAKALDALNDPG
WRHDDASWIQAT-NSPVWDTMLAIMALHDAKAEERFTPQMDKALGWLLDRQVR--VKGDWSILPDVEPGGWAFEYANDFYPDTDDTAVALIALASCRHRP
E--WKERGVEEAIARAVRWLVGMQSSCGGWGAFDKDNNKTL---LSPFCDFGEA-LDPPSVDVTAHILEAFGILG-------LPRDLPCIQRALAYVRAE
QDPQGPWFGRWGVNYVYGTGAVLPALAAIGED--TQPYITKACDWLAAHQQDDGGWGESCASYMEAIGRG--KTTPSQTAWALMGLIAAARPQD-FAAIE
KGCRYLIDRQEPDGSWTEEEYTGGFPGAFMLRYDLYRQFFPIMALSRASRLITPN--
>tr|Q1QJY6|Q1QJY6_NITHX Squalene cyclase OS=Nitrobacter hamburgensis (strain X14 / DSM 10229) GN=Nham_2682 PE=4 SV=1
---------------------------------------------------------------------------------------------LGGSIGA
ATRGLLDLKQPDGHFVFELEADATIPSEYVLLRHYLGEVDA-A---LEAKIAVYLRRIQGAHGGWPLVHD-GFDMSASVKAYFALKMIGDSIDAP---HM
ARAREAILSRGGAANVNVFTRFLLSLFEVLTWRSAPVLPIEIMLLPMWSPFHINKISYWARTTMVPLMVLAALKPRARN-PRI----RELFLQDPAVGTP
---------KR----TLF--NSLDWIL-RK----IEPL-PKRLRARAIEKAIAFVEERNGEDGLGAIFPPMVVMMYDALFPPEH--PPRAVARRGIDKLL
IGK-DEAYCQPC-VSPIWDTALTCHALLEAGGP-E--SGAGKSLDWLLPKQELV-LKGDWAVRPDVRPGGWAFQYANAHYPDLDDTAVVVMAMDRVRRND
----RSDKYNEAIARGREWIEGMQSRDGGFAAFDADNLEYY---LNPFSDHAAL-LDPPTEDVTARCVSMLAQLGET----V--RSSPSMAAGVDYLRRT
QLKEGSWYGRWGLNYIYGTWSVVCALNAAGVDHQ-DPAMRKAVDWLVSIQNADGGWGEDAVSYRL-GFEGA-PTTASQTAWALLALMAAGE--E-NPAVA
RGMKYLIDTQTK-GLWDEQRFTAGFPRVFYLRYHGYSRFFPLWALARYRNLRSTN--
>tr|G7D301|G7D301_BRAJP Squalene-hopene cyclase OS=Bradyrhizobium japonicum USDA 6 GN=BJ6T_67630 PE=4 SV=1
---------------------------------------------------------------------------------------------LESSIAS
ATQGVLGFQQSDGHWVFELEADCTIPAEYILLRHYLAEVDA-V---LEAKLGNYLRRVQGAHGGWPLVHD-GFDMSASVKSYFALKMIGDSVDAP---HM
VRAREAIHARGGAINSNVFTRFLLAMFGVMTWRAVPVLPIEIVLLPFWSPFHLNKISYWARTTMVPLMVLAALKPLAKN-PKV----DELFLQDPRIGMT
---------AK----VLF--RALDGIL-RV----IEPM-PKSLRQRAIDAALAFIEERNGEDGMGAIYPPMAVMMYDALKDENY--PPRAVTRRGIDKLL
FNG-DEAYCQPC-VSPVWDTTLTAHALLEAGGD-T--PAAKQGLDWLIPKQELE-VKGDWAVRPDVRPGGWAFQYNNAYYPDLDDTAVVVMSMDRMRREH
----GATGYDAAIDRGREWIEGMQSDDGGWAAFDVNNLEYY---LNPFSDHGAL-LDPPTEDVTARCISMLAQLGET----E--TTSKHVADGVAYLRKT
QHPEGSWYGRWGMNFIYGTWSVLCALNMAGVRHD-DPMIRKAADWLASIQNKDGGWGEDAVSYRL-GWEAA-PSTASQTAWALLALMAAGE--D-HPAVA
RGVEYLIATQNK-GLWDEQRYTAGFPRVFYLRYHGYPKFFPLWALARYRNLRNTN--
>tr|Q218A7|Q218A7_RHOPB Squalene cyclase OS=Rhodopseudomonas palustris (strain BisB18) GN=RPC_1720 PE=4 SV=1
---------------------------------------------------------------------------------------------LDASIES
ATNALLGYRQPDGHWVFELEADCTIPAEYVLLRHYLGEVDA-A---LEAKIANYLRRVQGAHGGWPLVHD-GFDMSASVKGYFALKMIGDDIDAP---HM
AKAREAIRSRGGAIHSNVFTRFLLSMFGITTWRSVPVLPVEIMLLPMWSPFHLNKISYWARTTIVPLMVLAALKPRAVN-RLI----DELFLQDPKIKMP
---------AK----KLF--AGIDAVL-RT----IEPL-PKRLRDHAIKLAVDFVEERNGEDGLGAIYPPMAVMMYKVLFPEDH--PPRAITRRGIDKLL
IGE-DEAYCQPC-VSPVWDTALTCHALLEVGGE-A--PPAKRGMDWLLPKQVLD-LKGDWAVRPNLRPGGWAFQYNNAHYPDLDDTAVVVMAMDRSRRAT
----GSREYDEAIARAREWIEGMQSDDGGWAAFDVNNLEYY---LNPFSDHGAM-LDPPTEDVTARCVSMLSQLGET----A--ASSKAVADGVEYLRRT
QLPDGSWYGRWGLNYIYGTWSVLCALNAAGVDHQ-DPVIRKAVTWLASVQNPDGGWGEGAESYRL-RYEQA-PTTASQTSWALLGLMAAGE--D-SPVVA
RGVEYLKSTQTG-GLWDEQRYTAGFPRVFYLRYHGYAKFFPLWALARYRNLRSTN--
>tr|A0A0D7QJM7|A0A0D7QJM7_9BRAD Squalene--hopene cyclase OS=Bradyrhizobium sp. LTSPM299 GN=UP10_00235 PE=4 SV=1
---------------------------------------------------------------------------------------------METSISR
ATEALMGYRQSDGHWVFELEADSTIPAEYVLLRHYLAEVDA-A---LEAKIANYLRRVQGAHGGWPLVHD-GFDMSASVKSYFALKMIGDSVDAP---HM
VRAREAIRSRGGAAGSNVFTRFMLALYGVVTWRAVPVLPIEIMLLPMWSPFHINKISYWARTTIVPLMVLAALKPRAKN-PKV----DELFLQDPKIGMT
---------PK----YLF--RSLDAVL-RV----VEPM-PKRMRQRAIDAALAFTEERNGEDGMGAIYPPMAVMMYEALKDETY--PPRAVTRRGLDKLL
IAE-HEAYCQPC-VSPVWDTALTCHALQEVGGD-E--ARMKEGLDWLKPRQVLE-LKGDWAVAPNVRPGGWAFQYNNDHYPDLDDTAVVVMAMDRAQRQT
----GSKEYDVAIARGREWIEGLQSRDGGWAAFDANNLEYY---LNPFSDHGAL-LDPPTEDVTARCVSMLGQLGVT----A--ATSKVMADGIAYLRRT
QLAEGSWYGRWGLNYVYGTWSVLSALNVAGVDHT-DPMIRKAVEWLLSVQNRDGGWGEDAVSYRL-GYETA-PSTSSQTAWALLGLMAAGE--G-NPAVS
RGVEYLKATQSE-GLWDEQRYTAGFPRVFYLRYHGYSKFFPLWALARYRNLSSTN--
>tr|V5PU73|V5PU73_9BURK Squalene--hopene cyclase OS=Pandoraea pnomenusa 3kgm GN=U875_17020 PE=4 SV=1
---------------------------------------------------------------------------------------------LESGIER
SIAALLDLQQDDGHWLFELEADSTIPAEYVLLRHHLGEVDA-E---LEGKIAAYLRRIQGEHGGWPLFQD-GFDMSASVKAYFALKMIGEPIDAP---HM
VRAREAILSRGGAQNSNVFTRILLALYGVLDWKAVPMMPVEIMLLPKWFPFHLSKVSYWARTVIVPLLVLQARRPLARN-PKV----DELFIGNPKVGPP
---------KR----TFF--SGVDHVL-RA----LDPC-PKRLRQKSIDRAVAFVEERNGEDGLGAIYPAMAVMMYDVLYPEDH--PSRAIARKSVEKLV
PA--HETYVQPC-LSPVWDTALSAHALLETGDK-R--EMAGKGLEWLIPLQILD-VRGDWISRPNVRPGGWAFQFANPHYPDVDDTAVVAMAMDRYEKLA
GKDASTRPMRHAIDRGTEWVIGMQSSNGGWGAFEPENTHLY---LNPFSDHGAL-LDPPTVDVSARCLSMLAQLPPS----P--ERRASAELALKYILDD
QEADGSWYGRWGMNYVYGTWSAMCGLRAAGLPPE-HPALARAAQWLISIQNADGGWGEDGDSYKL-GYESA-PSTSSQTAWALLGLMAAGK--N-DPAVK
RGIDYLLDTQND-GLWDEALYTAGFPRVFYLRYHGYRKFFPLWALARYRNLTVRN--
>tr|E5AV67|E5AV67_BURRH Plasmid pBRH01, complete sequence OS=Burkholderia rhizoxinica (strain DSM 19002 / CIP 109453 / HKI 454) GN=RBRH_03441 PE=4 SV=1
---------------------------------------------------------------------------------------------LEQAIRS
ATNALLDAQHDDGHWLFELEADATIPAEYVLMVHYLGEPDP-V---LEAKIGAYLKRIQGEHGGWPLFHD-GFDMSASVKAYFALKMIGEPLDAP---HM
KRARDAILARGGAAKSNVFTRILLALYGILDWRAVPMMPVEIMLLPTWFPFHLSKVSYWARTVIVPLLVLQAKRPRARN-PRI----DEIFVGSPRIGPI
---------SK----SFF--STIDALL-RK----LDPY-PKQSRQKAIDAAVHFVDARNGEDGLGAIFPAMVVLMYDVLYPPDH--PHRAIARKSIDKLL
IH--HEAYCQPC-LSPVWDTALTAHALLETGEP-R--EHAAKGLDWLLPLQVLD-TRGDWISRATVRPGGWAFQFANPHYPDVDDTAVVAMAMDRVEKLQ
---VR-DRYRNAIDRACEWVVGMQSHNGGWGAFEPENTHLY---LNPFSDHGAL-LDPPTVDVSSRCLSMLAQLPST----P--QRQTSASRAKHYILAD
QEDDGSWYGRWGMNYIYGTWSALCGLRAAGVAPD-TLPLRRAAHWLRSIQNPDGGWGEDGDSYKL-GYERA-PSTASQTAWALLGLMAAGC--H-DEAVA
RGIAYLLDTQND-GLWDETLFTAGFPRVFYLRYHGYRKFFPLWALARYRNLAVRN--
>tr|K5XY04|K5XY04_9PROT Squalene-hopene cyclase OS=Acidocella sp. MX-AZ02 GN=MXAZACID_00290 PE=4 SV=1
---------------------------------------------------------------------------------------------LDDAIEQ
ARASLRTEQRADGHYCYELEADATIPAEYVLLEHYLD-IDD-G---LQAKIGVYLRRIQGCDGGWPLFHG-GMDLSCSVKAYFALKAIGDSPEAP---HM
RRARAAIRAAGGAERSNVFTRFQMALFGAVPWTACPVIPVEAVLMPDWFPFTMRKVSYWSRTVMVPLMVLAAVKPRARN-PRV----DELFVTPPDVKDW
---------IR----PAF--KILDDVL-RI----AEPA-PTRTREKAVRKAIDWSIERNGEDGLGAIYPAMATMMFDHF---DA--AHFDIAWNAVRKLL
VG--TEAYCQPC-LSPIWDTALAGHALAEAGDK----DALAAACDWLIPRQELE-LVGDWADTPGTRPGGWAFQYNNPHYPDVDDTAVVAMLLHRAG---
-----DPKYAESIARAREWIIGMQSTNGAWGAFDINNDRQY---LNPFADHGAL-LDPPTEDVSARCISFLAQLGH-----A--EDQPAIQRGIAYLRET
QKPDGSWFGRWGTNYIYGTWSVLCALNAARIPHD-DPMMEKAAAWLISKQRQDGGWGEDCETYADEHGVAA-QSLPSQTAWALLGLMAAGL--E-HEAVH
RGIQYLQSTQGS-GSWSEAPYNAGFPRVFYLKYHGYPRFFPVLALSRYQRLIARN--
>tr|A0A0D6PH32|A0A0D6PH32_9PROT Squalene--hopene cyclase OS=Acidocella aminolytica 101 = DSM 11237 GN=Aam_039_006 PE=4 SV=1
---------------------------------------------------------------------------------------------LDNSIEL
ARASLTAEQRTDGHYCYELEADATIPAEYVLLEHYLD-IDD-G---LQAKIGVYLRRIQGCQGGWPLFHG-GMDLSCSVKAYFALKALGDSPQAP---HM
VRARKAILAAGGAERSNVFTRFQMALFGAVPWEACPVIPIEAVLMPDWFPFTMRKVSYWSRTVMVPLMFLASRKPLARN-PRI----DELFRTNPAVKDW
---------IR----PVF--KVLDDVL-RV----AEPF-PKGSRAKAEAKARDWIIERNGEDGLGAIYPAMATMMFDYL---DK--DNFDIAWGSVRKLL
VK--DEAYCQPC-LSPVWDTALAGHALAEAGEA----QAVAEACDWLIPRQELN-VVGDWADTPGTRPGGWAFQYNNPHYPDVDDTAVAAMLLHRAG---
-----DPKYAEAISRAREWIIGMQSTNGAWGAFDINNDRQY---LNPFADHGAL-LDPPTEDVSARCISFLAQLGY-----T--EDRPAIERGIAYLRET
QKPDGSWFGRWGTNYIYGTWSVLCALNVAGVAHN-DPMMIKATAWLLAKQREDGGWGEDNESYGDEHGHAA-ESLPSQTAWALLGLMAAGM--D-HEAVK
RGIGYLQAVQGE-GSWKEAPYNAGFPRVFYLKYHGYPRFFPLLALSRYKQLLASN--
>tr|F7S6H4|F7S6H4_9PROT Squalene--hopene cyclase OS=Acidiphilium sp. PM GN=APM_1925 PE=4 SV=1
---------------------------------------------------------------------------------------------LDQAISR
AHARLSAEQRADGHYVYELEADATIPAEYVLLEHFLD-IDP-E---LEARIGVFLRGIQGNPGGWPLFHD-GMDISASVKAYFALKAIGDDPDAP---HM
RRAREAILARGGAARTNVFTRIQLALFGAVPWRACPVMPVEIMLLPDWFPITIWKISYWSRTVIAPLLVLLTERPIARN-PRV----DELFVTPPDVTDY
---------IR----YLF--KAIDSAL-RP----LERH-PARSRKRAIQAAIDFITPRNGEDGLGAIYPAMAVMMYHTLYSPDH--PDYATAWASVRKLV
DASYGASYVQPC-LSPVWDTSLAAHALAEAGSP--GDAQLAAACDWLIPRQILD-VKGDWAYKPDAPPGGWAFQYNNAHYPDVDDTAVVGMILDRNG---
-----DPAHREAVERARQWILGMQSRSGGWGAFDSDNEFHY---LNPFADHGAL-LDPPTADVTARCISFLAQLGH-----A--EDRPAIERGVAYLRRE
QEQDGSWFGRWGTNYIYGTWSSLCALNAAGVAQD-DPMMVRAVEWLLARQRPDGGWGEDCETYAHAPGEYH-ESLPSQTAWALLGLMAAGQ--E-HEAVA
RGIAWLQSVQED-GSWTEQPYNAGFPRVFYLRYHGYPRFFPLLAMARYRNLARGN--
>tr|Q0BQ97|Q0BQ97_GRABC Squalene--hopene cyclase OS=Granulibacter bethesdensis (strain ATCC BAA-1260 / CGDNIH1) GN=GbCGDNIH1_2107 PE=4 SV=1
---------------------------------------------------------------------------------------------LEQAVLR
ASMALHRKQQTDGHWVFELEADATIPAEYVLLEHFLD-IDD-D---LERKIGVYLRRIQG-HGGWPLFHE-GFNLSASVKAYYALKAIGDDPDAP---HM
RRAREAILAAGGAERSNVFTRIQLALFGQIPWRGVPVMPAELMIAPKWFPINMWKVSYWSRTVIAPLLVLMDRKPKARN-PRV----RELFLHDPDIRDW
---------IR----HFF--KYLDSVL-RV----VEPV-LKPMRPRSIRLAVDFVRERNGEDGLGAIYPAMAVMMYDVLYSPDH--PEAAIAWESVRKLL
IK--DEAYCQPC-LSPIWDTGLSGHAMAEAEGA--VSPGVAAACDWLRNRQITD-VVGDWAERPGVQPGGWAFQYNNAHYPDVDDTAVVAMLLHRQG---
-----DPAHEESIRKAREWIIGLQCRDGGWGAFDADNDKDY---LNPFADHGAL-LDPPTADVTARCISFLAQLGN-----P--EDKPVIDRAMAWLRKE
QEADGSWFGRWGTNYIYGTWSVLCAMNVAGMPHD-DPAIRRAVNFLVATQREDGGWGEDEETYDPAPGRYK-ESTPSQTAWALIGLMAAGE--E-HEATR
RGIAYLQATQKP-GEWDEAAYTAGFPRVFYLKYHGYRQFFPLMALSRYKNLRSSN--
>tr|A0A0D6PC48|A0A0D6PC48_9PROT Squalene--hopene cyclase OS=Acidisphaera rubrifaciens HS-AP3 GN=Asru_0853_02 PE=4 SV=1
---------------------------------------------------------------------------------------------LVRSVAR
ASDALRRRQRDDGHWVFELEADATIPAEYVLLEHYLD-IDP-D---LQDRIGVYLRAAQG-HGGWPLFHA-GFDLSCSVKAYYALKLIGDDPEAP---HM
RRAREAILAHGGAARANVFTRAQLALFGQVPWRAVPVMPVEIMRLPRWFPFHLSKVSYWSRTVIVPLIVLMALRPQARN-PRI----AELFTTPPEVRDW
---------IR----RLF--KGIDRVL-RA----VEPR-PRGLRKRSIESAVAFVVERNGEDGLGAIYPAMAVMMFDALYAPDH--PHAAIAWASVRKLL
VQ--DRAYCQPC-LSPIWDTGLAGHAVAEADGI--ADDGLAAACTWLRGREVRD-VVGDWAIRPGLAPGGWAFQYNNAHYPDVDDTAVVGMLLHRQG---
-----DPAHAAAIERARAWIVGMQSRNGGWGAFDADNTHYV---LNPFADHGAL-LDPPTADVTARCVSFLAQLGR-----A--EDAPVIARALDYLRRE
QEPYGAWFGRWGTNYIYGTWSVLCALNAAGVPAG-DPMVRRAVDWLVSVQRPDGGWGEDEESYAAAPGTYH-ESTPSQTAWAVLGLMAAGE--A-HPAVA
RGIAWLTATQQA-GEWAELPYTAGFPRVFYLRYHGYRLFFPLLALARYRNLRRSN--
>tr|B5ZLQ8|B5ZLQ8_GLUDA Squalene-hopene cyclase OS=Gluconacetobacter diazotrophicus (strain ATCC 49037 / DSM 5601 / PAl5) GN=Gdia_1825 PE=4 SV=1
---------------------------------------------------------------------------------------------IDQAVDA
AHAALGRRQQDDGHWVFELEADATIPAEYVLLEHYLD-IDP-A---LEERIGVYLRRIQGDHGGWPLYHG-GFDVSATVKAYFALKAIGDDIDAP---HM
ARARAAILDHGGAERSNVFTRFQLALFGEVPWHATPVMPVELMLLPRKALFSVWNMSYWSRTVIAPLLVLAALRPRAIN-PRV----PELFVTPPDVRDW
---------IR----RLF--KYVDIAL-RP----AERL-PDATRQRAIKAAVDFIEPRNGEDGLGAIYPAMAVMMYRALVPDSD--PRAATAWEAVRRLL
EL--GEAYCQPC-VSPIWDTGLAGHAMIEAASG-PTKKKLAAAAEWLRERQILN-VKGDWAICPDVPPGGWAFQYNNDYYPDVDDTAVVGMLLHREG---
-----DPANDEALERARQWIIGMQSSNGGWGAFDIDNNLDF---LNPFADHGAL-LDPPTADVTARCISFLAQLGH-----P--EDRPVIERGIAYLRTD
QEREGCWFGRWGTNYIYGTWSVLCAYNAAGVAHD-DPSVVRAVDWLRSVQREDGGWGEDCASYEG-PGIYT-ESLPSQTAWAVLGLMAVGL--D-DPAVM
RGMAYLTRTQKD-GEWDEEPYNAGFPKVFYLRYHGYRQFFPLLALSRYRNLASSN--
>tr|A0A0D6N754|A0A0D6N754_9PROT Squalene--hopene cyclase OS=Acetobacter indonesiensis 5H-1 GN=Abin_002_118 PE=4 SV=1
---------------------------------------------------------------------------------------------LDRAVKN
AHAALGKRQQADGHWVYELEADATIPAEYVLLEHYLN-IDD-G---LQQKIGNYLRRTQSDHNGWALYHN-GFDLSASVKAYFALKAIGDDINAP---HM
QRAREAIHDHGGAERTNVFTRCQMALFGDVPWRATPVMPVELMLLPRKAFFSIWNMSYWSRTVIAPLLVLAALRPIAIN-PRI----RELFVTPPEVKDW
---------IR----RAF--KGLDAVL-RP----VLPF-PTKTHEKAIKAAIDFIEPRNGEDGLGAIYPAMAVMMYRALVPDED--PRAVTAWKAVQKLL
IK--DEAYCQPC-VSPIWDTGLSGHAMLEAASG-PTLIELRKASAWLRDKQILD-VEGDWAIKPGLAPGGWAFQYGNDHYPDVDDTAVVGMLLHREG---
-----DPANAEALARARQWIIGMQSTNGGWGAFDIDNDKEL---LNPFSDHGAL-LDPPTADVTARCISFLAQLGN-----P--EDQPIIDRAIEYLRKD
QEEDGSWFGRWGTNYIYGTWSVLCAFNAAGISHD-DPAVVKAVEWLRSVQRPEGGWGEGCESYEG-HGTYG-ESLPSQTAWAVLGMMAAGR--D-DPAVS
RGIAWLAEQQDD-GEWHEDPYNAGFPKVFYLRYHGYKQFFPLMAMARYRNLESSN--
>tr|D5QAC9|D5QAC9_KOMHA Squalene-hopene cyclase OS=Komagataeibacter hansenii ATCC 23769 GN=GXY_00319 PE=4 SV=1
---------------------------------------------------------------------------------------------LDAAVTR
AQAALGQRQKEDGHWVFPLEADATIPAEYVLLEHFLD-IDP-A---LEKRIGIYLRRIQGAHGGWPLYEN-GFDLSASVKAYFALKAIGDDINAP---HM
IRARAAILHHGGAERTNVFTRLQLALFGEVPWHAAPAMPVELMLMPRKALFSVWNMSYWSRTVIAPLLVLGAVRPCALN-PRV----PELFVTPPDVRDW
---------VR----HVF--QYLDRVL-HP----AERF-PRKTRRRAIRAAVDFVEKRNGVDGLGAIYPAMAVMMFRALVPDTD--PRAATAWEAVQRLL
NQ--RETYCQPC-ASPIWDTGLAGHAMIESATG-PTKEKLAKAAQWLRGRQILD-VKGDWAMCPDVKPGGWAFQYNNDYYPDVDDTAVVGMLLHRAG---
-----DPANAEALERARHWIIGMQSSNGGWGAFDIDNDLDV---LNPFADHGAL-LDPPTADVTARCISFLAQLGH-----G--VDRPCIERGLDYLRTE
QEADGSWFGRWGTNYIYGTWSVLCALNAANVAKD-DPMVVRATDWLRCRQRADGGWGEGCESYEG-HGEYG-QSLPSQTAWAVLGMMAAGL--D-DAAVA
RGVAYLARTQGT-GEWAEEPYNAGFPKVFYLRYHGYRQFFPLMALSRYRNLQNSN--
>tr|A0A0D6MMP7|A0A0D6MMP7_9PROT Squalene-hopene cyclase OS=Tanticharoenia sakaeratensis NBRC 103193 GN=Tasa_028_088 PE=4 SV=1
---------------------------------------------------------------------------------------------VAAGVDR
ARAALSERQRDDGHWVFELEADATIPAEYVLLEHYLD-IDD-A---LEARIGVYLRRIQGVHGGWPLYHG-GFDLSASVKAYFALKCIGDDVDAP---HM
VRAREAILDHGGAARSNVFTRFQLALFGEVPWAATPAMPVEIVLLPRSAFFSMWNMSYWSRTVMTPLLVLRALAPCAIN-PRV----QELFVKPPTVQDW
---------IK----RVF--KHLDQVL-RP----VEAR-PQALRDRAIKAAVDFIEPRS-EGGLGAIYPAMAVMMYRALVPDSD--PRAEQAWRGVRDLL
ENVGPETYCQPC-VSPVWDTGLAGLAMMEAGSG-SVRERLQGASEWLRDRQILD-VKGDWAVRPDLPPGGWAFQYENDYYPDVDDTAVVGMLLHRQS---
-----DPKNAEAIERARIWIIGMQSTNGGWGAFDIDNDLDL---LNPFADHGAL-LDPPTADVSARCVSFLAQLGH-----P--EDRPVIERGLAYLRAE
QEVEGCWFGRWGTNYIYGTWSVLCALNAAGVPHD-DPMVRRAVAWLESVQRADGGWGEDCATFEG-PGVYD-ESLPSQTAWAVLGLMAVGQ--D-SEAVK
RGIAFLLSRQKD-GEWDEQPYNAGFPKVFYLKYHGYRQFFPLMALSRFRNLQTSN--
>tr|B7L324|B7L324_METC4 Squalene-hopene cyclase OS=Methylobacterium extorquens (strain CM4 / NCIMB 13688) GN=Mchl_5491 PE=4 SV=1
---------------------------------------------------------------------------------------------TLRAIAG
AGRALGRHQRRDGHWVFELEADATIPAEYVLLEHYMD-ITP-E---RQARIGAYLRRIQG-HGGWPMFHA-GFNISASVKAYCALKAIGDDPQAP---HM
VRARQAILGHGGAERANVFTRIQLALFGAIPWRGVPVMPVEIMHLPKWFFFNIWAMSYWARTCVVPLLVLQARKPRARN-PRV----DEIFRTEPDVRDW
---------IR----VVF--KHIDTVL-RW----TEPL-SKVARESAIFKAVDFVEERNGEDGLGAIYPAMALMMYDVLYPEDD--PRCVTIWKAIDKLL
ET--EEVYCQPC-VSPVWDTSLSGHAMIEAART-GAQAELDAACDWLVARQVKD-VRGDWAERPDAEPGGWAFQYRNDHYPDVDDTAVVAMLLHRNG---
-----RPEHAEAIEKARRWVVGVQSRNGGWGAFDADNDREF---LNPFSDHGAL-LDPPTADVTGRCISFLSQLGH-----E--EDRPVIERALAYLRAE
QERDGSWYGRWGTNYVYGTWTVLCGLNAAGIPHD-DPMVRRAVDWLVSIQRADGGWGEDERSYDV-YVENA-ESLPSQTAWAMLGLMSVGQ--D-HPAVL
RGAAYLQRTQGP-GEWQERAYNAGFPRVFYLKYHGYRLFFPLFALSRLHNLQRGN--
>tr|A0A0D6Q9D2|A0A0D6Q9D2_KOMXY Squalene--hopene cyclase OS=Komagataeibacter xylinus NBRC 13693 GN=Gxy13693_022_004 PE=4 SV=1
---------------------------------------------------------------------------------------------LDQAVTR
AHAALGKRQADDGHWVFDLEADATIPAEYVLLEHYLD-IDP-A---LEQRIGIYLRRIQGAHGGWPLYQD-GFDLSASVKAYFALKAIGDSVHAP---HM
VRARQAILDHGGAERTNVFTRIQLALFGDVPWDAAPVMPVEIMLLPRRALFSVWNMSYWSRTVIAPLLVLAALRPTAVN-PRV----HELFVTPPGVRDW
---------IR----HVF--RYADAVL-RP----AERL-PEKTRRRAIKAAVDFIEPRNGLDGLGAIYPAMAVMMFRALISDDD--PRAKAAWEAVQRLL
NQ--KETYCQPC-VSPIWDTGLAGHAMIEAASG-PTKRKLATAARWLRERQILN-VRGDWSIRPDVRPGGWAFQYANDYYPDVDDTAVVGMLLHRDG---
-----DPANAEAIARAREWIIGMQGSNGGWGAFDVDNSRDV---LNPFADHGAL-LDPPTADVTARCISFLAQLRQ-----V--EDHGAIERGIAYLRRE
QEKDGSWFGRWGTNYIYGTWSVLCALNAAGMPHG-DPMIIRAVDWLRRHQRADGGWGEGCESYEG-HGDYK-QSLPSQTAWAVLGMMAVGL--D-DPAVA
RGIAWLGRTQGR-GEWKEEPYNAGFPRVFYLRYHGYRQFFPLLALARYRNMQLSN--
>tr|A0A0D6MSG3|A0A0D6MSG3_ACEAC Squalene--hopene cyclase OS=Acetobacter aceti NBRC 14818 GN=Abac_009_052 PE=4 SV=1
---------------------------------------------------------------------------------------------LDRVVER
AHAALGGKQNDDGHWVFELEADATIPAEYVLLEHFLD-IDQ-P---LEDKIGVYLRRIQGEHGGWPLYHD-GFNISATVKAYYALKCIGDDINAP---HM
QRARQAVLDHGGAERTNVFTRFQLALFGEIPWHGTPVMPVELMLLPRSAFFSVWNMSYWSRTVIAPLLVLAALRPVAVN-PRV----QELFVTPPDVKDW
---------IK----HAF--KVLDQVL-RP----VVKL-PQKVHKKAIRASVDFIEPRNGIDGLGAIYPAMAVMMYRALVPDSD--PRANTAWESVRALL
DH--DEVYCQPC-VSPIWDTGLAGHAMMEAGSG-PTQEKMAKAAEWLRDRQILD-VKGDWAIRPDLEPGGWAFQYRNDYYPDVDDTAVVGMLLHRQN---
-----DPANDKAIERARKWIVGMQSTNGGWGAFDVDNNKEL---LNPFSDHGAL-LDPPTADVTARCISFLAQLGH-----A--EDRPVIERALDYLRGD
QEQDGSWFGRWGTNYIYGTWSVLCALNAAGVSHD-DPMVVRAVEWLRSVQRPDGGWGEGCESYED-RGRYK-ESLPSQTAWAVLGMMAVGR--D-DPAVK
RGIAWLSKQQGE-GEWEEEPYNAGFPKVFYLKYHGYKQFFPLLAVSRYRNLQSSN--
>tr|A0A0D6N1C2|A0A0D6N1C2_9PROT Squalene--hopene cyclase OS=Acetobacter cibinongensis 4H-1 GN=Abci_007_137 PE=4 SV=1
---------------------------------------------------------------------------------------------LDRVVST
AQAALGKRQQKDGHWVYELEADATIPSEYVLLEHYLD-IDD-P---LQQKIAAYLRRTQSDHGGWALYHN-GFDLSASVKAYFALKATGEDINAP---HM
RRAREAILDHGGAERSNVFCRCQLALFGEVPWHATPVMPIELMLLPRKAFFSVWNMSYWSRTVIAPLLVLAALKPKAIN-PRI----QELFVTKPDVKDW
---------IR----RMF--KGLDTVL-RP----LIPL-PAKTHQKAIKATIDFIEPRNGEDGLGAIYPAMAVMMYRALVPDTD--PRAVTAWKAVQKLL
IK--DEAYCQPC-VSPIWDTGLSGHAMLEAASG-PTLAELRKASAWLREKQILT-VKGDWAIKPDLAPGGWAFQYGNDHYPDVDDTAVVGMLLHREG---
-----DPANAEALERARQWIIGMQSTNGGWGAFDIDNDKEI---LNPFSDHGAL-LDPPTADVTARCISFLKQLGH-----V--EDQPVIDRAIAYLRAE
QEEDGSWFGRWGTNYIYGTWSVLCAFNVAGVSHD-DPSVVRAVEWLRSVQREDGGWGEGCETYEG-HGVYS-ESLPSQTAWAALGLMAAGR--D-DPAVG
KAMTWLASQQDE-GEWHEDPYNAGFPKVFYLRYHGYKQFFPLMALARYRNLESSN--
>tr|A0A089NXS0|A0A089NXS0_9RHIZ Squalene-hopene cyclase OS=Methylobacterium oryzae CBMB20 GN=shc PE=4 SV=1
---------------------------------------------------------------------------------------------ILQSIAG
AGRALLRRQRGDGHWVFELEADATIPAEYVLLEHYMD-ITP-D---RQAKIGVYLRRIQG-HGGWPMFHA-GFDLSASVKAYCALKAIGDDPQAP---HM
IRARQAILDHGGAERANVFTRIQLTLFGAIPWRGVPVMPVEVMYLPKWFFFNIWAMSYWARACVVPLLVLQALHPRARN-PQL----DEIFRNSPEICDW
---------IR----VAF--KYIDTFL-RV----TEPV-SKIARGKAIAKAVAFVDERNGEDGLGAIYPAMALMMYDVLYPRDD--PRCITIWKAIDKLL
EN--DEIYCQPC-VSPVWDTSLSGHAMIEACRS-GAQKDLDAACDWLVARQVTE-VRGDWAERPDLRPGGWAFQYRNDHYPDVDDTAVVAMLLHRNG---
-----RPEHAEAVEKARGWIVGMQSRNGGWGAFDADNDREF---LNPFSDHGAL-LDPPTADVTGRCVSLLAQLGR-----E--EDRPVIHRALTYLRAE
QEPDGSWYGRWGTNYIYGTWSVLCALNAAGVPHD-DAMVRRAVDWLISIQRADGGWGEDERSYDV-YVENA-ESLPSQTAWAMLGLMAAGQ--D-HPAVS
KGAAYLQSSQGA-GEWQERAYNAGFPRVFYLKYHGYRLFFPLFALSRFHNLKRGN--
>tr|S6CZB3|S6CZB3_ACEPA Shc protein OS=Acetobacter pasteurianus 386B GN=shc PE=4 SV=1
---------------------------------------------------------------------------------------------LDRAVLS
AHTALSQAQQDDGHWVYELEADATIPAEYILLEHFMD-IDD-A---LEQKIAIYLRRIQSEHGGWPLYHN-GFDLSATVKAYFALKAVGDDINAP---HM
QRAREAILDHGGAERSNVFTRSQLALFGEVPWRATPVMPVELMLLPAKAFFSVWNMSYWSRTVIAPLLVLAALRPVAAN-PRV----RELFVTPPEVQDW
---------IR----YVF--KGLDSVL-RP----VVPF-PEKTHKKAIQAALDFIEPRNGKDGLGAIYPAMAVMMYRAMVPDED--PRAKTAWEAVQALI
EK--DEAYCQPC-VSPIWDTGLSGHAMIEAASG-PTVAELKKASAWLRSKQILN-VKGDWAVNPNLAPGGWAFQYGNDYYPDVDDTAVVGMLLHREG---
-----DPTNAEAIERARTWIVGMQSTDGGWGAFDIDNNKDV---LNPFADHGAL-LDPPTADVTARCISFLAQLRN-----P--EDEPVIQRGLEYLRKE
QEKDGSWFGRWGTNYIYGTWSALCALNAAGVSHD-DPAVVKAVEWLRSVQRADGGWGEGCESYEG-HGTYG-ESLPSQTAWAVLGLMAAGR--D-DPAVT
RGIAWLADQQDA-GEWHEDPYNAGFPKVFYLRYHGYKQFFPLMALARYRNLESSN--
>tr|G6F2E3|G6F2E3_9PROT Squalene-hopene cyclase OS=Commensalibacter intestini A911 GN=CIN_17890 PE=4 SV=1
---------------------------------------------------------------------------------------------LDHAILQ
AQNVLAGLQNDDGHWVFELEADATIPAEYVLLEHFLD-IDT-K---LEEKIGVYLRRIQGDHGGWPLYYG-GFDISASVKAYFALKAIGDDVDAP---HM
KRARTAILAHGGAETANVFTRTQLALFGEVPWRATPAMPVELMLMPKWALFSVWNMSYWSRTVIAPLVLLVSLKPRAVN-RHI----QELFVTHPEIKEW
---------IK----YLF--KYLDKVV-RP----VEKI-PKFFRRYAQKKAIEFIRERNGEDGLGAIYPAMAVMGFRCFIPDSD--PRAEIAWQSVKKLL
IK--DEAYCQPC-VSPIWDTALTGHAMIETASG-VTMEKLAKATEWLKDRQILD-VKGDWAICPDVAPGGWAFQYRNDYYPDVDDTAVVGMLLHREG---
-----KPEYKESIERARQWIIGMQSSNGGWGAFDIDNNKML---LNPFSDHGAL-LDPPTVDVAARCISFLAQLGH-----P--EDKPVIDRGIQYLRDE
QEKCGAWFGRWGTNYIYGTWSALCAFNAVGISDQ-DPAVQKAVDWLTCVQRPDGGWGESEESYEG-PGQYH-TSLPSQTAWALLGLMAAKQ--K-HPAVQ
KGIRWLMETQET-GQWAEDPYNAGFPRVFYLRYHGYRQFFPLFALSRYRNLQSSN--
>tr|A0A023D1B6|A0A023D1B6_ACIMT Squalene--hopene cyclase OS=Acidomonas methanolica NBRC 104435 GN=Amme_002_003 PE=4 SV=1
---------------------------------------------------------------------------------------------VARAVDS
AHAALARRQNEDGHWVFELEADATIPAEYVLLEHYLD-IED-A---LEQRIGVYLRRIQGDHGGWPLYHG-GFDMSASVKAYFALKAIGDDIDAP---HM
KRAREAILDRGGAARTNVFTRIQLALFGEVPWRAVPVMPVELMLMPKAAFFSMWNMSYWSRTVVAPLLVLRAMEPRAIN-PRV----RELFVTPPEVTDW
---------IR----RVF--KHLDTVL-RP----IEPH-PKAVRERAIRTAIEFIEPRS-EGGLGAIYPAMAVMMYRALVPDDD--PRAAQAWRGVRDLL
HN--DETYCQPC-VSPVWDTGLSGLAMAEASSG-PTRAMLRKSMAWLRDRQILD-VKGDWAICPDVRPGGWAFQYENDHYPDVDDTAVVGMLMHRED---
-----PEGNAEAIERAREWVIGMQSRGGGWGAFDIDNDLEA---LNPFADHGAL-LDPPTADVSARCVSFLAQLGR-----P--EDRPVIERGLEYLRRE
QEPEGCWFGRWGTNYIYGTWSVLCAFNVAGVPHD-DPAVKRAVAWLEETQRADGGWGEDCASYEG-PGVYK-ESLPSQTAWAVLGLMAVGR--D-TEAVR
RGIAYLVTMQDE-GEWHEQPYNAGFPKVFYLRYHGYKQFFPLMALSRYRNLGLSN--
>tr|W7E3Y2|W7E3Y2_9PROT Squalene-hopene cyclase OS=Commensalibacter sp. MX01 GN=COMX_07200 PE=4 SV=1
---------------------------------------------------------------------------------------------LDRAILQ
AQNILANRQNEDGHWVFELEADATIPAEYVLLEHFLD-IDT-E---LQEKIGVYLRRIQGDHGGWPLYYG-GFDISASVKAYFALKAIGDDVDAP---HM
IRARTAILAHGGAETANVFTRTQLALFGEVPWYATPAMPVELMLMPKWALFSVWNMSYWSRAVIAPLVLLVSLKGRAVN-RYI----QELFITPPDIKEW
---------IK----YLF--KYLDKVV-RP----MEKL-PSFLRKHAQKKTVEFIEKRNGEDGLGAIYPAMAVMAFRCMMRDDD--PRAVIAWKSVKKLM
VK--DEAYCQPC-VSPIWDTALTGHAMMETASG-ITMDKLAKASKWLKERQILD-VKGDWAICPDVAPGGWAFQYNNDYYPDVDDTAVVGMLLHREG---
-----KPEHQESIERARHWIIGMQSSNGGWGAFDIDNDKML---LNPFSDHGAL-LDPPTVDVAARCISFLAQLGH-----P--EDKAVIDRGMNFLRAE
QESFGAWFGRWGTNYIYGTWSALCAFNAVGISNQ-DPAVKKAVDWLLCVQRPDGGWGEGEESYEG-PGQYH-TSLPSQTAWALLGLMAAGQ--N-HPAVQ
KGIQWLMENQEE-GQWDEKPYNAGFPRVFYLRYHGYRQFFPLFALSRFRNLQSSN--
>tr|A0A060QEJ6|A0A060QEJ6_9PROT Squalene--hopene cyclase OS=Asaia platycodi SF2.1 GN=ASAP_1078 PE=4 SV=1
---------------------------------------------------------------------------------------------VRQAIDS
AHAALSNRQNDDGHWVFELEADATIPAEYVLLEHYLD-IDD-E---KQARIGNYLRRTQGSHGGWALYHD-GFDLSASVKAYFALKAVGDDIEAP---HM
KRAREAILDRGGAARANVFTRIQMALFGEVPWRATPVMPVELMLMPKAALFSMWNMSYWSRSVVAPMLVLRTLEPRAIN-PRI----QELFITPPEVKDW
---------IR----HVF--KKVDTML-RP----IEPR-PAALRKKAIKVALDFIEPRG-EGGLGAIYPAMAVMMYRGMVPDND--PRVELAWKGIQELL
SN--DETYCQPC-VSPVWDTGLSGLALAEASSG-PTREALRRSMDWLRKRQILN-VKGDWAICPDVRPGGWAFQYENDYYPDVDDTAVVGMLLNRED---
-----PEGNQEAISRAREWIVGMQSTNGGWGAFDIDNDLDA---LNPFADHGAL-LDPPTADVSARCVSFLCELGF-----P--EDRPVIERGLAYLRRE
QEPEGCWFGRWGTNYIYGTWSTLCAFNIAGVPHD-DPAVERAVAWLESVQREDGGWGEDCASYEG-PGEYD-KSLPTQTAWAILGLMAVGR--E-TPAVK
RGISYLVAQQNG-GEWEEQPYNAGFPKVFYLRYHGYKQFFPLMALSRFRNLGLSN--
>tr|A0A087PPX6|A0A087PPX6_9PROT Squalene--hopene cyclase OS=Acetobacter malorum GN=AmDm5_1732 PE=4 SV=1
---------------------------------------------------------------------------------------------LDRVVQN
AHAALGQRQQADGHWVYELEADASIPAEYILLEHYLN-IDE-A---LEQKIAVYLRRTQSEHGGWALYHN-GFNLSSSVKAYFALKATGEDINAP---HM
RRAREAILDHGGAERTNVFTRIQLALFGDVPWRATPVMPVELMLLPRKAFFSIWNMSYWSRAVIAPMLVLAALRPIAIN-PRI----RELFVTPPEVTDW
---------IR----RVF--KGLDSVL-RP----TLGL-PSKTHEKAITAAIDFIEPRNGKDGLGAIYPAMAVMMYRALVPDTD--PRAVTAWDAVQGLL
HK--DEVYCQPC-VSPIWDTGLSGHAMLEAASG-PTLTELRKASKWLRDKQILD-VKGDWAVNPNVAPGGWAFQYGNDYYPDVDDTAVVGMLLHREG---
-----DPANNESIERARQWIIGMQSRDGGWGAFDIDNSKEL---LNPFSDHGAL-LDPPTADVTARCISFLAQLGH-----G--EDRPVMERALTYLRKE
QEEDGSWFGRWGTNYIYGTWSALCAFNAAGVSHD-DPAVVKAVEWLRSVQRADGGWGEGCESYEG-HGTYG-ESLPSQTAWAVLGLMAAGR--D-DPAVT
RGISWLAAQQDE-GEWHEDPYNAGFPKVFYLRYHGYKQFFPLMAVARYRNLESSN--
>tr|A0A067Z7J3|A0A067Z7J3_GLUOY Squalene-hopene cyclase OS=Gluconobacter oxydans DSM 3504 GN=GLS_c24030 PE=4 SV=1
---------------------------------------------------------------------------------------------INHAIEG
AQAALGGKQKSDGHWVYELEADATIPAEYVLLEHYLD-IDP-E---KQAKIGVYLRRIQGDHGGWPLYHD-GFDLSATVKAYFALKAIGDDINAP---HM
RIAREAILDHGGAARTNVFTRIQLALFGEVPWDATPVMPVELMLLPRKAFFSVWNMSYWSRAVIAPLLVLNALRPKAIN-PRI----QELFVKPPSVKDW
---------IR----RFF--KHLDSAL-RP----VLPL-PRSVHKKALKAASDFIEPRS-RGGLGAIYPAMAVMMYRAQVPDSD--PRAKTAWDAIQDLL
DH--DEIYCQPC-VSPVWDTGLSGLAMIEAASG-PTLVALKKSAEWLREHQILD-VKGDWAIAPDLRPGGWAFQYENDYYPDVDDTAVVAMLLHRVD---
-----PENSREAISRAREWIIGMQSTNGGWGAFDIDNDHEL---LNPFSDHGAL-LDPPTADVSARCISFLAQLGD-----P--DDRPVILKAIEYLRSE
QEPEGCWFGRWGTNYIYGTWSVLCALNIAGVPHD-DPMVLRAVNWLESVQRPDGGWGEDCATYEG-AGTYK-KSLPSQTAWAVLALMAVGR--E-SEAVK
RGVAYLVSQQNE-GEWQEEAYNAGFPKVFYLRYHGYKQFFPLTALARYRNLGVSN--
>tr|M9M937|M9M937_GLUTH Squalene-hopene cyclase OS=Gluconobacter thailandicus NBRC 3255 GN=NBRC3255_0353 PE=4 SV=1
---------------------------------------------------------------------------------------------VTRAIEG
AHAALGKRQKDDGHWVFELEADATIPAEYVLLEHYLD-IDQ-N---KQDKIGVYLRRIQGEHGGWPLYFG-GFDLSATVKAYFALKAIGDSIDAP---HM
RRAREAILDHGGAARSNVFTRIQLALFGEVPWDATPVMPVELMLLPRTAFFSVWNMSYWSRAVLAPMLAVGALKPQAIN-PRI----QELFVKPPAVKDW
---------IR----RAF--KHLDTAL-RP----VLPL-PKKIHDKALKAAISFIEPRS-LGGLGAIYPAMAVMLYRALVPDSD--PRVVTAWQSIQDLL
HK--DEIYCQPC-VSPVWDTGLSGLAMMEAASG-ATLAKLKKSAEWLRDRQILD-VKGDWAVTPDLRPGGWAFQYENDYYPDVDDTAVVGMLLHRVD---
-----PEENREAIERAREWIIGMQSTNGGWGAFDVDNDLEM---LNPFSDHGAL-LDPPTADVSARCISFLCQLGH-----P--EDRPVIDKALDYLRKE
QEKEGCWFGRWGTNYIYGTWSVLCALNIAGISYD-DPMVKRAVNWLEDIQRSDGGWGEDCATYEG-PGIYK-ESLPSQTAWAVLALMAVGR--N-SEAVK
RGINFLMSRQDE-GEWQEEAYNAGFPKVFYLRYHGYKQFFPLQALSRYRNLGTSN--
>tr|A0A060Q9W5|A0A060Q9W5_9PROT Squalene--hopene cyclase OS=Saccharibacter sp. AM169 GN=SACS_1306 PE=4 SV=1
---------------------------------------------------------------------------------------------VEQAVRA
SHTALGKRQKSDGHWVFELEADATIPSEYVLLRHFLD-IDV-E---LEQKIGVYLRRTQGEHGGWSLYTD-GFDLSASVKAYFALKMIGDDPEAP---HM
RKARAAILHHGGAERSNVFTRIQLALYGEVPWDAVPVMPVELMLLPRKAFFSVWNMSYWSRAVIAPLLILAAYRPLALN-PRV----QELFRRPPAIRDW
---------IR----RVF--TGLDKLI-RP----LVPF-PHSVHEKAIRVTIDFIEKRS-GGGLGAIYPAMAIMMYRTLVPDDD--PRVVQAWEAVQGLL
VK--DEAYCQPC-VSPVWDTGLSGLAMLEASTG-ATAIALKKAAAWLRERQILD-VRGDWAIAPTLRPGGWAFQYENDYYPDVDDTAVVGMLLHRID---
-----PEENRTAIERAREWIIGMQSSNGGWGAFDIDNNMEV---LNPFSDHGAL-LDPPTVDVSARCISFLSQLGH-----P--EDREVIRKGLDYIRSE
QEKSGSWFGRWGTNYIYGTWSVLCALNIAGISHD-DPMVRRAVAWLESVQNDDGGWGEDCASYEG-QGLYK-ESLPTQTAWATLGLMAVGR--D-SEAVR
RGMAYLMQAQDD-GEWHEAPYNAGFPKVFYLRYHGYKQFFPLMALSRYRNLADSN--
>tr|A0A0A0CWW1|A0A0A0CWW1_9PROT Squalene--hopene cyclase OS=Inquilinus limosus MP06 GN=P409_30400 PE=4 SV=1
---------------------------------------------------------------------------------------------LDDAIGR
GVGGLLDLQREDGHWAFILEADATIPAEYILLRHFLG-VDR-E---KEAKLADYIRSIQSRHDGWPLWHD-GFNISASVKAYFALKAAGDDPDAP---HM
VRARAAILKAGGAARSNVFTRILLALFEQVPWRAVPVMPAQIMVLPSWFPFQLNKVSYWSRTVIVPLLVIMAKKPRPVN-PGL----QELMVEPPEVKNW
---------HV----RFF--RRLDGVL-RP----IEPF-PR--RETSIRKAVEFVTERNGEDGLGAIYPAMAVMMFKCLYPDDH--PDLRIAWASVEKLV
T---GVTYAQPC-LSPVWDTALTAHALLESDDP-EAVARAKRGLDWLVPRQVLD-VKGDWAERPNVRPGGWAFQYNNAHYPDLDDTAVVVMAMHRAD---
-----PERYREAIDRGVEWIVGLQSRNGGWAAFEVDNTYHY---LNPFADHGAL-LDPPTSDVTARCLSMLGQLGR-----R--LDDPVVARGVEFLRQE
QEADGSWFGRWGTNYIYGTWSVLCALNAIGIDPQ-DPMIRRAVAWMVSQQREDGGWGESGDSYYEKEMTPA-TSTASQTAWAVLALMAVGE--K-HPAVE
RGVAWLSAHQRA-GLWDEPSFTAGFPRVFYLRYHGYPAFFPTWALSRYRRLRDSN--
>tr|A0A061QEQ9|A0A061QEQ9_9PROT Squalene--hopene cyclase OS=alpha proteobacterium Q-1 GN=shc PE=4 SV=1
---------------------------------------------------------------------------------------------LDQVIDD
ALTALKTRQQKDGHLVFDLEADATIPAEYIFLNHFLD-REP-E---LERKLARYIRSIQQDGGGWPLYHG-GPDISASVKAYFALKLTGDDPDAP---HM
KKARALIKNLGGAEKTNVFTRYALALFGEVPWRAVPVMPVELMLMPRWFPANMWRFSYWSRTVIAPLLILAALKPRAIN-PTT----RELFIIPPEIRDW
---------QQ----KAF--LQLDKIL-QK----LEPH-PAKTRRKAIERALGFFTERNAEDGLGAIFPAMAVMAMEALYPKDH--EALVTAKKSIRLLV
DG--GESFVQPC-LSPIWDTSLSLHALLESGEA-PAGETVKAAGDWLTSKQILD-VKGDWALAPDLRPGGWAFQYNNDHYPDVDDTAVVAMALHRTQ---
-----DPNYKEAIDRAEEWIIGMQSSNGGWGAFDIDNDDHY---LNPFADHGAL-LDPPTEDVSARCLSFLGQLGH-----D--QNHEAVARGVAYLKKL
QEDDGCWYGRWGTNYIYGTWSVLAALNAVGEDMT-APYVRKAVEWLKARQNPDGGWGESGDSYYN-KRDPA-PSTPSQTSWALLGLMAAGE--E-DACVA
RGIGWLLDHPRTKGRWEEPWYNAGFPRVFYLRYHGYSHYFPIWALSRYRVLSRSN--
>tr|Q1LFR1|Q1LFR1_RALME Squalene-hopene cyclase OS=Ralstonia metallidurans (strain CH34 / ATCC 43123 / DSM 2839) GN=sqhC PE=4 SV=1
---------------------------------------------------------------------------------------------LDAGIAH
VVESLLAQQQSDGHWVYELEADATIPAEYILMVHYLGEPDL-V---LEGKIANYLRRIQNADGGWPLFHA-GSDISASVKGYFALKMAGDNPEAE---HM
RRARAAIHAMGGAEASNVFTRTLLALYGVMPWQAVPMMPVEIMLLPEWFPFHLSKVSYWARTVIVPLLVLNSLRPQARN-PRI----DELFVRPCQTRLP
---------RR----GVF--RTLDAVV-RM----AEPL-PRGLRQRAIERAREFTVERNGEDGLGAIFPAMVVLMFDVLVPESD--PNRAIARRSIDKLL
IK--DEAYCQPC-LSPVWDTSLAAHALLEVGEP-R--AAAARGLDWLLPLQELE-LRGDWTVRPNVRPGGWAFQYANPHYPDVDDTAVVAAAMDRVDKGD
----RSNRYDEAVSRACEWIVGMQSSNGGWGAFEPENTHLY---LNPFADHGAL-LDPPTADVSARCLAMLCQLGQM----P--ANSEPAARALRYLLDE
QEADGSWFGRWGTNYIYGTWSALCGLNAAGIGTD-APEMKRAAQWLLSIQNEDGGWGESGDSYKL-GYEKA-PSTASQTAWAMLGLMAAGA--D-HPALV
RGVEYLLRTQAS-GFWDEPYFTAGFPRVFYLRYHGYSRFFPLWALARFRNLLRDG--
>tr|G9ZUF2|G9ZUF2_9PROT Squalene-hopene cyclase OS=Acetobacteraceae bacterium AT-5844 GN=HMPREF9946_00166 PE=4 SV=1
---------------------------------------------------------------------------------------------VEDAIHH
ATAALGRYQREDGHWVFELEADATIPAEYVLLRHYLGEDDL-T---LERKIGNYLRRIQG-HGGWPLFHG-GFDISASVKAYFCLKMIGDDPDAP---HM
VRAREAILAQGGAARCNVFTRILLAQFGELPWSAVPAMPVEMILLPRWFPVHLSKMSYWARTVIVPLLVLQAVKRRARN-PRI----QELFRPGVRV-GT
----------P----AFF--NGLDVVL-QK----VEPL-PRGQRQQAIARCEAFVTERNGEDGLGAIYPAIAVMMYDALHGPEH--PGRAIARQAIEKLL
VGE-DEAYCQPC-VSPVWDTALASHAMLEVGGE-A---AALRGLEWLRPRQELE-VKGDWAERPDVRPGGWAFQYRNAHYPDLDDTAVVVMAMDRARYQF
---GAGGGYDIAIDRGAEWVVGLQSTNGGWGAFDVDNNHDF---LNPFADHGAL-LDPPTADVSARCVSMLAQLGR-----T--D-TPEMRRALDYLERE
QEKDGSWFGRWGVNYVYGTWSALCALNAAGFDAT-RPSMRRGADWLLSIQNEDGGWGEDCDSYKL-GYEPA-PSTASQTAWALLGLMAAGE--D-NPAVA
RGIEWLRRMQGE-GLWPQEAYTGGFPRIFYLRYHGYPKFFPLWALARYRNLRAGN--
>tr|A0A069PTF2|A0A069PTF2_9BURK Squalene--hopene cyclase OS=Burkholderia glathei GN=BG61_25310 PE=4 SV=1
---------------------------------------------------------------------------------------------LDASVAK
AADALLAAQHADGYWLYELEADATIPAEYVLLVHYLGEPDL-T---LEAKIGRYLRRIQLEDGGWPLFTE-GMNVSASVKAYFALKMIGDSPDAE---HM
QRARRAILAAGGAEQSNVFTRLQLALFGAMPWRAVPMMPVEMMLLPMWFPFHLTKVSYWARTVIVPMLVLNAKRPIARN-PRV----DELFNEAPVTELL
---------PR----AFF--RGVDSVL-RT----VDGL-PRRSRERAIREAVRFVDERNGEDGLGAIYPAMAVMMYDVLYPADH--PNRAIARRSLEKLL
IDE-GEAYCQPC-LSPVWDTSLVAHALLETGLP-K--AAVSRGLEWLRPLQILD-VRGDWVSRPNVRPGGWAFQFANPHYPDVDDTAVVAMAMERADREN
---GT-AIYTEAIARAREWVVGMQSSDGGWGAFEPENTHYH---LNPFSDHGAL-LDPPTVDVSARCLSMLAELGET----P--ANSEPARRALDYILRA
QERDGSWYGRWGMNYVYGTWSALCALNAAGLPAS-DARVRRAAEWLISIQNEDGGWGEGGESYKL-GYEQA-PSTASQTSWALLGLMAAGV--D-HPAVA
RGVAYLQATQRA-GLWDEARFTAGFPRVFYLRYHGYRKFFPLWALTRYRNMTRDD--
>tr|A0A069IDL0|A0A069IDL0_9BURK Squalene--hopene cyclase OS=Cupriavidus sp. SK-3 GN=CF70_004465 PE=4 SV=1
---------------------------------------------------------------------------------------------LQGTLDR
ALDALLATQRPDGHWVFELEADATIPAEYVLLVHYLGEPDT-V---LEARIARYLRRIQNADGGWPLFHQ-GSDISASVKAYFALKMIGDDTESE---HM
RRARASIHAQGGAEASNVFTRTLLALYGVMPWQAVPMMPVEIMLLPLWFPFHLSKVAYWARTVIVPLLVLNSLRPQARN-PRV----DELFIRPCQARLA
---------PR----TVF--SALDAGL-RV----AEPL-PRSLRKRAIARAEKFVRERNGEDGLGAIFPAMAVMMFDVLVPRTD--PDVAVARASIEKLL
VH--DEAYCQPC-LSPVWDTSLASHALLEVGGP-R--AAAERGLQWLRPLQELD-VRGDWIVRPDVRPGGWAFQYANPHYPDVDDTAVVAMAMDRAARSG
AAASHRARYDEAVSRAREWVAGMQSGNGGWGAFEPENTHEF---LNPFADHGAL-LDPPTADVSARCLSMLGQLGEN----S--ASSPAFKRALRYLLDE
QMADGSWYGRWGMNYIYGTWSALCALNAAGLPPA-APEMRRAAAWLVSIQNADGGWGEDGSSYRL-GYEPA-PSVASQTAWALLGLMAAGE--D-HPAVA
RGIDYLVRTQQA-GLWNEARFTAGFPRVFYLRYHGYARFFPLWAVARYRNLRRDG--
>tr|A0A0D5MPI8|A0A0D5MPI8_BURGL Squalene-hopene cyclase OS=Burkholderia glumae LMG 2196 = ATCC 33617 GN=shc PE=4 SV=1
---------------------------------------------------------------------------------------------LDAAITR
ATDALLAAQQADGHWIYELEADSTIPAEYVLLVHYLGEPNL-E---LERKIARYLRRVQLPGGGWPLFTD-GPDVSASVKAYFALKMIGDDANAE---HM
VRARNAIHAMGGAEMSNVFTRIQLALFGVVPWFAVPMMPVEIMLLPQWFPFHLSKVSYWARTVTVPLLVLSAKRPLARN-PRV----DELFVAPPVAGLL
---------PR----ACF--RLLDGLL-RL----TDGL-PRYTRERAIRQALQFVDERNGEDGLGAIYPAMAVMMYAALYPEDH--PNRATARRAIEKLL
IHD--EAYCQPC-LSPVWDTSLAAHALLETGEP-R--AAAIRGLDWLRPLQILD-VRGDWISRPDVRPGGWAFQYANPHYPDVDDTAVVTLAMDRVAKLA
---QT-DAYRDAIARAREWVVGMQSSDGGWGAFEPENTHQY---LNPFSDHGAL-LDPPTADVSGRCLSMLAQLGET----A--ANSAPARRALDYLLAE
QGADGSWYGRWGMNYIYGTWSALGALNAAGLPFD-DPRVKRAAQWLLSIQNPDGGWGEDGDSYKL-GYERA-ASTASQTAWALLGLMAAGE--E-HPAVA
RGIAWLAAQQRE-GLWDEARFTAGFPRVFYLRYHGYRKFFPLWALARYRNLRRTG--
>tr|A0A069P3Z2|A0A069P3Z2_9BURK Squalene--hopene cyclase OS=Burkholderia grimmiae GN=BG57_29735 PE=4 SV=1
---------------------------------------------------------------------------------------------LDHAVTE
ATDAMLAAQHPDGYWLYELEADATIPAEYVLLVHYLGEADI-A---LEAKIGRYLRRIQLDDGGWPLFTD-GMDVSASVKAYFALKMIGDSPDAE---HM
QRARRAILAAGGAEKANVFTRILLALFGVVSWRAVPMMPVEIMRLPVWFPFHLSKVSYWARTVIVPLLVLNAKRPKARN-PRV----DEVFRDSPVTGMP
---------HR----AFF--RVVDSIL-RA----TDGA-PKAGRERAIAEAVRFVDERNGEDGLGAIFPAMAVMMYDVLYPPEH--PHRAIARKSIDKLL
SDE-GEAYCQPC-LSPVWDTSLASHALLETGMP-K--AAVARGLEWLRPLQILD-VRGDWFLRPNVRPGGWAFQFANPHYPDVDDTAVVAMAMERADREN
---GT-AMYGEAISRAREWVVGMQSSDGGWGAFEPENTQFY---LNPFSDHGAL-LDPPTVDVSARCLSMLAQLGET----P--SNSEPARRALEYVVRD
QERDGSWYGRWGMNYIYGTWSALCALNAAGVAPT-DARVKRGAEWLIGIQNADGGWGEDGDSYKL-GYEQA-SSTASQTAWALLGLMAAGL--E-HPAVA
RGIAYLVRTQTK-GLWDEARFTAGFPRVFYLRYHGYRKFFPLWALARYRNLTREG--
>tr|K8R1H2|K8R1H2_9BURK Squalene-hopene cyclase OS=Burkholderia sp. SJ98 GN=BURK_035959 PE=4 SV=1
---------------------------------------------------------------------------------------------LDAAVNH
ATDALLAAQHPEGYWLYELEADATIPAEYVLLVHYLGEADE-K---LEAKIGRYLRRIQREDGGWPLFTD-GMDVSATVKAYFALKMIGDSPDAP---HM
ERARAAILAAGGAEKVNVFTRILLALFGVVSWRAVPMMPVEIMRLPMWFPFHLSKVSYWARTVIVPMLVLNAKRPRARN-PRV----DEVFTNPPVTGMP
---------SR----AFF--RVVDSIL-RV----ADPL-PKAGRERAIDEAVRFVDERNGEDGLGAIFPAMAVMMYDVLYPPEH--PNRAIARKSLDKLL
IDP-GEAYCQPC-LSPVWDTSLAAHALLETGVP-K--AAVRRGLDWLVPLQILD-VRGDWVSRPDVRPGGWAFQFANPHYPDVDDTAVVAMAMERADREN
---GT-ALYGESIARAREWVVGMQSSDGGWGAFEPENTQFY---LNPFSDHGAL-LDPPTVDVSARCLSMLAQLGET----S--LNSEPARRAFEYIVRD
QERDGSWYGRWGMNFIYGTWSAMSALNAAGVAPT-DTRMKRAADWLIGIQNDDGGWGEDGDSYKL-GYEQA-PSTASQTAWALLGLMAAGL--E-HPAVA
RGVGYLLKTQQK-GLWDETRFTAGFPRVFYLRYHGYRKFFPLWALARYRNLTRDG--
>tr|F1Z7H4|F1Z7H4_9SPHN Squalene hopene cyclase OS=Novosphingobium nitrogenifigens DSM 19370 GN=Y88_1518 PE=4 SV=1
---------------------------------------------------------------------------------------------VDLAVDR
AANAMVEAQRPDGHWVFELEADCTIPAEYVLLRHFLGEDDL-E---LEAKIGRYLRRIQSDHHGWGLFHG-GFDISASVKAYYALKMIGDDINAP---HM
ARARAAIRAAGGAAAVNVFTRIQLALFGAGSWDAVPTMPPELILLPRWFPIHLSKMSYWARTVIVPLLVIGAKKPLARN-PRI----EELYTTT-KAPLA
---------SK----IGF--NALDRVL-KA----GDNL-PKARRAQAIQTCVDWVIERNGEDGLGAIYPAMAVMMFDLLYPEDH--PARAIARKSVENLL
IHE-DEAYCQPC-VSPVWDTALAAHAMLEAGGE-T--ARAKAGLDWLKPLQVLD-VEGDWAERPGVRPGGWAFQYNNAHYPDLDDTAVVVMAMDRAG---
------VEDRMPIDRGVEWTVGLQSKNGGWGAFDADNTYDY---LNPFADHGAL-LDPPTADVSARCISMLAQLGES----K--D-SPRMAAAIEYLRKE
QEPEGSWFGRWGVNYIYGTWSVLCALNAAGIAPS-DPMVARAVSWLRQIQNADGGWGEDCESYAL-GHIPA-PSTASQTAWALLALMAAGD--D-TDAVR
RGIAWLVANQDE-GLWGQELYTGGFPRVFYLRYHGYPKYFPLWALARYRNLRRSN--
>tr|Q46RD2|Q46RD2_CUPPJ Terpene synthase:Squalene cyclase OS=Cupriavidus pinatubonensis (strain JMP 134 / LMG 1197) GN=Reut_B4954 PE=4 SV=1
---------------------------------------------------------------------------------------------LDAGIGH
AVDALLAQQNADGHWVYELEADATIPAEYVLMVHYLGEPDL-S---LEARIARYLRRIQNADGGWPLFHE-GSDISASVKAYFALKMAGDDPQAA---HM
ARAREVILAMGGAETSNVFTRTLLALYGVMPWQAVPMMPVEIMLLPQWFPFHLSKVSYWARTVIVPLLVLNSLRPQARN-PRV----DELFLGSRDVRLP
---------PR----ALF--HGADVLL-RT----AEHV-PRGLRRRAIDAAKAFVRERNGEDGLGAIFPAMAVMMFDVLVPPDD--PDRAIARRSIDKLL
VH--DEAYCQPC-LSPVWDTALAAHALLEASEP-R--AAVTRALDWLRPLQVLD-VRGDWTVRPDVRPGGWAFQYANPHYPDVDDTAVVVAAMHRAARTD
H-SGRADPNAEATARAIEWIVGMQSANGGWGAFEPENTHLY---LNPFADHGAL-LDPPTADVSARCLSMLCQTGAT----P--DKSEPAARALQYLLAE
QLPDGSWFGRWGTNYIYGTWSALCALNAAGLGPD-APPLRRAAEWLVAIQNPDGGWGEDGDSYKL-GYETA-PSVASQTAWALLALMAAGQ--A-HPAVT
RGIDYLLRTQQA-GLWHEPRFTAGFPRVFYLRYHGYARYFPLWALARYRNLERSG--
>tr|W4P299|W4P299_9BURK Squalene--hopene cyclase OS=Burkholderia caribensis MBA4 GN=K788_000709 PE=4 SV=1
---------------------------------------------------------------------------------------------LDAAVTR
ATDAILAAQQDDGHWVYELEADATIPAEYVLLVHYLGEPNV-E---LEQKIARYLRRIQLADGGWPLFTD-GMDVSASVKAYFALKMIGDPVDAE---HM
VRARECILAHGGAEAANVFTRILLALFGVVTWYAVPMMPVEIMLLPKWFPFHLSKVSYWARTVIVPLLVLNAKRPVARN-PRV----DELFRGAPVTGLL
---------PR----AFF--RAVDGVL-RV----TDGL-PKRSRERAIKAAVDFVDERNGEDGLGAIFPAMAVMMYDVLYPADH--PKRAIARQSIDKLL
IHE--EAYCQPC-LSPVWDTSLAAHALLETGDT-R--EAAERGLAWLRPLQILD-VRGDWISRPDVRPGGWAFQYNNAHYPDVDDTAVVALAMHRSAALT
---QS-DVDADAIARAREWVVGMQSSDGGWGAFEPENTQYY---LNPFSDHGAL-LDPPTADVSGRCLSMLAQLGEM----P--ATSEPARRAYDYLLKE
QEDDGSWYGRWGMNYIYGTWTALCALNAAGISHD-DARIRRAAQWLVSIQNADGGWGEDGTSYKL-GYEKA-PSIPSQTAWALLGLMAVGY--D-HPAVA
RGIEYLKSEQRD-GLWDETRFSAGFPRVFYLRYHGYRKFFPLWALARYRNLTRAG--
>tr|M4S1C0|M4S1C0_9SPHN Squalene-hopene cyclase OS=Sphingomonas sp. MM-1 GN=G432_09180 PE=4 SV=1
---------------------------------------------------------------------------------------------VEKAVDR
AAVALIAAQRDDGHWVFELEADATIPAEYLLLRHYLGEEDL-A---LEAKVGRYLRRIQN-DGGWPLFHG-GMDLSATVKAYFALKLIGDDGDAP---HM
ARARAAVLAAGGAEAANVFTRIQLALYGAGPWAAVPEMPVEMILLPRWFPIHLSKMSYWARTVIVPLLVLMALRPRARN-PRT----DELYRSKEPAPIA
---------SR----EGF--LALDKLL-KG----VRPF-PAGLRRRAIDRCVAWTRERNGEDGLGAIYPAMAVMMYDALYPPDH--PDRAIARASVEKLL
LDP-DEIYCQPC-VSPVWDTALAAHALMEAGGD-A--ARAAKGLAWLKPLQVLD-VKGDWAERPDVRPGGWAFQYRNDHYPDLDDTAVVAMAMDRARGRI
---VPGDGQDQAIARGREWVEGMQSRNGGWGAFDADNMAEY---LNPFADHGAL-LDPPTVDVTARCISMLAQLGEP----A--E-SPRMRAALAYLARE
QEADGSWFGRWGVNYVYGTWSALCALNAAGVDPQ-ELIVRRAVAWLEAIQNPDGGWGEDCDSYAL-GHRPA-PSTASQTAWALIGLMAAGE--D-GAAVQ
RGVGWLMRHQGT-GLWPQEHFTGGFPRVFYLRYHGYPRYFPLWAMARYRNLKRGN--
>tr|A0A095WEG9|A0A095WEG9_BURGA Squalene--hopene cyclase OS=Burkholderia gladioli GN=LA03_00890 PE=4 SV=1
---------------------------------------------------------------------------------------------LDIAVTR
ATDALLAAQQADGHWVYELEADATIPAEYVLLVHYLGEPNA-E---LERRIGRYLRRIQLPGGGWPLFTD-GPDVSASVKAYFALKMIGDDVEAE---HM
VRARQAIHAMGGAEMSNVFTRIQLALFGVVPWFAVPMMPVEIMLLPQWFPFHLSKVSYWARTVIVPLLVLNAKRPLAKN-PLV----DELFVNPPVTGLL
---------PK----LLF--RGVDGLL-RL----TDGL-PRYSRERAIRQAVQFVDERNGEDGLGAIYPAMAVMMYAALYPEDH--PNRAIARRSLDKLL
IKD-DEAYCQPC-LSPVWDTTLAAHALLETGEP-R--AAALRGLEWLRPLQILD-VRGDWVSRPHVRPGGWAFQYANPHYPDVDDTAVVVLAMDRAARLT
---QS-DVDREAIARAREWVVGMQSSDGGWGAFEPENTHHY---LNPFSDHGAL-LDPPTADVSGRCLSMLAQLGET----N--VNSQPAQRALGFLLAE
QEADGSWYGRWGMNYIYGTWSALGALNAAGLGHD-DPRVKRAAQWLLSIQNPDGGWGEDGTSYKL-GYEPA-TSTASQTAWALLGLMAAGE--D-HAAVA
RGIDWLIAEQKT-GLWDETRFTAGFPRVFYLRYHGYRKFFPLWALARYRGLKRAG--
>tr|F8EV08|F8EV08_ZYMMT Squalene-hopene cyclase OS=Zymomonas mobilis subsp. pomaceae (strain ATCC 29192 / JCM 10191 / NBRC 13757 / NCIMB 11200 / NRRL B
---------------------------------------------------------------------------------------------IEPVIEK
AAQALLDTQKQDGHWVFELEADATIPAEYILLRHYLGEEDL-E---LEAKIGRYLRRIQG-HGGWPLFYK-GFDISATVKAYFALKMIGDSPDEP---HM
QRAREEILAHGGAITSNVFTRLQLALYGAIPWETVPQMPVEMMLLPDWFPIHINKMSYWARTVLVPLLVLQAVRPLAKN-PRI----DELFVPGATVPAR
----------A----IGF--GALDKVL-HK----AESF-PKANRKKAIDACVNFVSERNGEDGLGGIYPAIAVMMYDALYPEDH--PERAIARKAVEKLL
FNPEDEIYCQPC-LSPIWDTALAAHAMLEVGGD-K--KAAIDALNWLEPQQILD-VKGDWAWKPDLRPGGWAFQYNNAYYPDVDDTAVVVMAMDRAGKLP
---EIGSKFEESKSRAIEWTLGMQSDNGGWGAFDANNTYYY---LNPFADHGAL-LDPPTVDVSARCVSMLAQAGKT----L--Q-DDDMKTAVHYLFQE
QEKDGSWFGRWGVNYIYGTWSALCALNAADIPHD-HLNIRRAVQWLESIQNEDGGWGEDCDSYAL-GYQPA-VSTPSQTAWALLGLMAVGE--D-STAVA
RGINWLANNQDE-GFWKEDYYSGGFPRVFYLRYHGYSKYFPLWALARYRNLSRAN--
>tr|A0A0A6QCF0|A0A0A6QCF0_9BURK Squalene--hopene cyclase OS=Burkholderia sacchari GN=NH14_14910 PE=4 SV=1
---------------------------------------------------------------------------------------------LDAAVTR
ATDAILADQRADGHWVYELEADATIPAEYVLLVHYLGEANL-E---LEAKIARYLRRIQLPGGGWPLFAE-GMDVSASIKAYFALKMIGDAEDAD---HM
VRAREAILAAGGAEKANVFTRILLALYGVVSWYATPMMPVEIMLLPKWFPFHLTKVSYWARTVIVPLLVLGAKRPVAKN-PRV----DELFRGAPVTGLN
---------ER----GFF--RAVDGVL-RI----TDPL-PNYLRQRAIDAAVAFVDERNGEDGLGAIFPAMAVMMYEVLYPADH--PHRAIARQSIEKLV
IH--DEAYVQPC-LSPVWDTSLAAHALIETGDA-R--EAARRGLEWLRPLQILD-LRGDWISRPATRPGGWAFQYANPHYPDVDDTAVVVAAMRRVDQID
---QT-SAYDEAIARGREWVVGMQSGNGGWGAFEPENTHEY---LNPFSDHGAL-LDPPTADVSGRCLSMLAQLGEL----P--ATSEPAQRAYNYILAE
QEADGSWHGRWGMNYIYGTWTALCALNAAGLAHT-DSRMKRAAQWLVAIQNDDGGWGEDGTSYKL-GYERA-PSTASQTAWALLGLMAAGE--N-HPAVA
RGVAWLQATQRE-GLWDETRFTAGFPRVFYLRYHGYRKFFPLWALARYRNLKRDG--
>tr|D0G7G4|D0G7G4_9MONI Terpene cyclase/mutase family member OS=Polypodiodes niponica GN=PNG PE=2 SV=1
---------------------------------------------------------------------------------------------LEEAIQR
SQEFLLAQQFPEGFWFGELEANVTIISHTVILYKLLGIEENF----PMYKFERYLRRMQCSHGGWEIAYGIGSYLSATIEAYIALRLLNVPQSDP---AL
QKALRVILDSGGVTKARIFTKICLALLGSFDWRGIPSLPPWLILCPTWFPLSIYEVSSWARGCIVPLLVILDKKPVFKV-SP-----DELYAEGREACK-
--------------IKFF--ITVDRV-FKM----MERLRVVPFRQWGIREAEKWILEREESGDYVNIFPAMFVMCMKVLYETTD--PVVQRALLGFKGFT
IETADECKVQST-VSPIWDTAFIVRALVDSGIPP-DHPALQKAGQWLLQKQIL--KHGDWAFQNHLAAGGWAFQSHNRWYPDADDSAAVMMALDCIELP-
----DEDVKNGAIARGLKWISALQSRNGGWAGYDKNCDQQW---INPFNDLNGI-LDVPTADVTARVLEMVGRLSRLGASIPHLLLPETIARGLAYLRRE
QEGEGCWWGKWGVNYIYGTCGALLALSQVAPT--HQEEIARGAKWLAQVQNRDGGWGESCFSYDDLKGQND-ASTASQTAWAVQGLLAAGDG-KEVEAIE
QGVQYLLATQRKDGTWHEAHFTGCFAQHFYVRYHYYAQHFPLSALGLYRTRILQH--
>sp|B3Y522|DCD_DRYCA Dammaradiene synthase OS=Dryopteris crassirhizoma GN=DCD PE=1 SV=1
---------------------------------------------------------------------------------------------LDEAIKR
SQDFLLSQQYPEGYWWAELEGNPTITSHTVILYKILGIEDEY----PMDKMEKYLRRMQCIHGGWELFYGDGGQLSVTIESYVALRLLNVPPTDP---AL
KKALKFIIDKGGVXKSRMFTKICLALLGCFDWRGIPSLPPWVMLLPGWFLSSIYETACWARGCVVPLIVVFDKKPVFKV-SP-----DELYAEGREACK-
--------------THFF--IAVDRV-FKM----MERLGVVPFQQWGIREAEKWLLEREDTGDFLGVYPPMFVVCMKTLYEVTD--PVVRRALLSFKKFS
IERADECSVQSS-LSPVWDTALVVRSLVESGLPP-DHPALQRAGEWLLQKQIT--KHGDWSFS---VAGGWAFQFFNRWYPDLDDSAVVVMALDCLKLP-
----NEDVKNGAITRCLKWISSMQCKGGGWAAFDKDNHQHW---INPFSDLKAM-VDPSTTDISARVLEMVGRLKLHGTDEAHFLPPESIARGLVYLRRE
QENEGCWFGRWGVNYIYGTCGALVALSLVAPM--HEEEIARGARWLVQVQNMDGGWGETCFSYNDLKGQGD-VSTASQTAWALQGLLAAGDG-KEVESIG
HGVQYLLSTQRKDGSWHESQFTGGFPIHFYLRYHFYAQHFTLSSLARYRTRLQAS--
>tr|D0G7G3|D0G7G3_9MONI Terpene cyclase/mutase family member OS=Polypodiodes niponica GN=PNT PE=2 SV=1
---------------------------------------------------------------------------------------------LEEAIKR
SQEFLLAHQHPEGFWWGDLECNVTSASHTLILYKILGIADRY----PLHKFEKYLRRMQCSHGGWEMSFGDGGYLSATIEAYICLRLLNVPQSDP---AL
QRALKNILARGGVTKARVFTKVCLALLGGFDWAALPSLPPWLMLFPAWFPWNIYEAASWARGCVVPLIVLLEKKPVFQV-KP-----DELYVEGRAACK-
--------------ANIF--VAADRA-FKL----MERFGAVPFRQWSIKEAKKWVLDREEMGDFIGYNPPMLAVCLKLWYEVTD--PLLQRALLAHKKLT
VETEDECWLQSS-QSPVWDTALVIPALVESGLPP-DHPALQKAGQWLLEKQIL--KHGDWALGGDDIGGGWAFQFVNSWYPDVDDSAAVVIALNCIKMP-
----DEDVKNGAIARCLKWIAFMQGRNGGWAAFDRDSNQRW---MDPFSDIEAM-LDVSTADVTARVLEMVGLMRLKHAKAHRHISTESIARGVDYLTKE
QEKEGCWWGRWGVNYIYGTRGALMGLSQVAAK--HKKEIARGAAWLVKVQNKDGGWGEACFSYDDTKGQNS-RSTASQTGWAMQGLLAAGEGRKEMEAVE
EGVQFLLDTQRKDGSWSEAEFTGGFPKHYYLKYHYFAQHFPLSALARYRARLLQL--
>tr|A8R7G4|A8R7G4_ADICA Terpene cyclase/mutase family member OS=Adiantum capillus-veneris GN=ACH PE=2 SV=1
---------------------------------------------------------------------------------------------LDEAIER
SQDFLLSLQYPEGYWWAELEANVTLTAQTIMLYKILGIDHKYP----IHKMKTYILRTQRAHGGWEIFYGDGGCLSTTIGAYMALRILGVPKTDP---VL
QKALKLIHSKGGVTKSRMFTKICLALLGCYDWKGIPSLPPWLVLLPSWFPFSLYDTASWVRGCVVPLTIIFDKKPVYKL-NPL---CDELYSEGKGARVH
----------L----NFF--VGLDHVF-KY----MENL-VVPFRQWGIKEAERWTLEREDSGDFHGIYPPMFIVSYSLLYEITD--PVVHRALESMRGFT
VERE-ECVVQSC-ISPMWDTAFVIRSLAESGL--QDHPALQKAGEWLLQKQAT--QHGNWFYKRTGRAGGWAFQFFNRWYPDVDDSAAVSMALNAIKLQD
D--DV---KKGAIKRCAEWISVMQCKDGGWAAYDCDNDREW---LNPFGDLKAM-IDPNTVDVTARVLEMVGRVKEAG-DASAILPPRAIARGLAYLRRE
QETEGCWYGRWGVNYIYGTSGALMALALVAPSTH-KEEIERGARWLVEVQNKDGGWGETCFSYNDLKGRNE-VSTVSQTAWALQGLLAAGD--LEVESIE
HGVQYLLSTQRKDGSWCEKHFTGGFPRFFYIRYHLYAGHFPLSALARYRDRVRAG--
>tr|K8GNP7|K8GNP7_9CYAN Squalene-hopene cyclase OS=Oscillatoriales cyanobacterium JSC-12 GN=OsccyDRAFT_1695 PE=4 SV=1
---------------------------------------------------------------------------------------------LNEIISR
SQNYLLSLQHPDGYWWAELESNVTMAAEVVLLHKIWGTDATRP----LHKIETYLRRQQREHGGWELFYGDGGELSTTVEAYMAMRLLGVPASDS---AL
QKAKTFILERGGITKTRIFTKFHLALIGCYDWAGLPSLPAWIMLLPSSFP--IYEMSSWARGSTVPLLIVFDKKPVYLV-DPI---TDELYAEGREARFE
----------L----DVF--VMLDGAF-KV----AESL-LVPFREEGIQAAERWVLEREPTGDWGGIIPAMLLLALRALYDAHD--PIVERGMQAVDRFA
IEKD-AYWVQPC-VSPVWDTALVMRSLVDSGI--ADHPALVKGGQWLLDAQIL--DYGDWAVNKVGKPGAWAFEFINRFYPDVDDSAVVVMALNAVQLPN
E--KL---KQQAIARAVQWIASMQCNPGGWAAFDLNNDADW---LNPYGDLKAM-IDPNTADVTARVLEMAGRLVQSS-APVSSLSRAAIDRALTYLRNE
QEPEGCWFGRWGVNYIYGTSGVLSALSLIAPDTH-QREIERGAAWLVTCQN-DGGWGETCFSYNNYMGQG--DSTASQTAWAITGLLAAGD--LEMEAIQ
RGVQYLVDTQRPDGSWDEDYFTGGFPCHFYLKYHLYLQHFPLTAIGRYRSRLIQQ--
>tr|Q8DGK8|Q8DGK8_THEEB Squalene-hopene-cyclase OS=Thermosynechococcus elongatus (strain BP-1) GN=shc PE=4 SV=1
---------------------------------------------------------------------------------------------LQQAIRA
SQDFLFSQQYAEGYWWAELESNVTMTAEVILLHKIWGTEQRLP----LAKAEQYLRNHQRDHGGWELFYGDGGDLSTSVEAYMGLRLLGVPETDP---AL
VKARQFILARGGISKTRIFTKLHLALIGCYDWRGIPSLPPWIMLLPEGSPFTIYEMSSWARSSTVPLLIVMDRKPVYGM-DPI---TDELYSEGRAVVWE
----------L----DVF--IGLDRVF-KL----FETL-IHPLREQGLKAAEEWVLEREASGDWGGIIPAMLLLALRALYAVDD--PIVQRGMAAVDRFA
IETE-EYRVQPC-VSPVWDTALVMRAMVDSGV--ADHPALVKAGEWLLSKQIL--DYGDWHINKKGRPGGWAFEFENRFYPDVDDTAVVVMALHAVTLPN
E--NL---KRRAIERAVAWIASMQCRPGGWAAFDVDNDQDW---LNPYGDLKAM-IDPNTADVTARVLEMVGRC-Q------LAFDRVALDRALAYLRNE
QEPEGCWFGRWGVNYLYGTSGVLTALSLVAPRYD-RWRIRRAAEWLMQCQN-DGGWGETCWSYHDLKGKG--DSTASQTAWAIIGLLAAGD--TATEAIE
RGIAYLLETQRPDGTWHEDYFTGGFPCHFYLKYHYYQQHFPLTALGRYARWRNLL--
>tr|B8HRM9|B8HRM9_CYAP4 Squalene/oxidosqualene cyclase OS=Cyanothece sp. (strain PCC 7425 / ATCC 29141) GN=Cyan7425_3575 PE=4 SV=1
---------------------------------------------------------------------------------------------LEKAIAA
SQEHLLSTQYPEGYWWAELESNVTMTAEVVLLHKIWKTDGTRP----MHKAEKYLRSEQREHGGWELFYGDGGDLSTSVETYTALRLLGVPASDP---AL
LKAKDFILRRGGISKTRIFTKLHLALIGCYDWRGLPSLPPWVMLLPENFPFTIYELSSWARGSTVPLLIVMDRKPVFSV-NPI---NDELYAEGRDVKFE
----------L----DLF--IELDGLF-KF----TEQN-LVPFREEGLRAAERWVLEREATGDWGGIIPAMLLLALRALYHPAD--PYVRRGMAAVDRFA
IETA-TYRVQPC-VSPVWDTALVMRGLIDSGL--PDHPAIVKAGEWLLEKQIL--AYGDWAVNKTGQPGAWAFEFENRFYPDVDDSAVVVMALQAAQLPD
E--DL---KQQAIERCVKWIATMQCKPGGWAAFDVDNDQDW---LNPYGDLKAM-IDPNTADVTARVLEMIGRS-G------VTTGEASVERALAYLRRE
QEVEGCWFGRWGVNYIYGTSGVLAALALIAPKSD-HAMIQRGADWLVRCQN-DGGWGETCRSYNDLKGQG--PSTASQTAWALIGLLAAGE--TAWGAID
RGINYLLATQQQDGRWDEDWFTGGFPGHFYLKYHLYQQHFPLTALGRYSSLTGLK--
>tr|B2IWZ4|B2IWZ4_NOSP7 Squalene/oxidosqualene cyclase OS=Nostoc punctiforme (strain ATCC 29133 / PCC 73102) GN=Npun_R6245 PE=4 SV=1
---------------------------------------------------------------------------------------------VAEAIAA
SQQYLLSIQNPAGYWWAELESNVTITAETVLLHKIWGTDQTRP----LHKVEAYLRQEQRQHGGWELFYGDGGELSTSVEAYMALRLLGVPATDP---AM
IRAQAFILQRGGISKTRIFTKLHLALIGCYNWRGIPSLPPWIMLLPKAFPVNIYEMSSWARSSTVPLLVVCDRKPVFIT-DPI---NDELYAEGIDVRWE
----------L----DLF--LTLDQGF-KW----AESL-LVPFREEGIKAAEKWILEREATGDWGGIIPAMLMLALRCLYDRSD--PIVERGLQAIDNFA
IETD-SYRVQPC-VSPVWDTAWVMRALVESGF--VDHPAVVKAGEWLLQKQIL--DYGDWAVNRQGKPGAWAFEFENRFYPDVDDSAVVVMALHLAKLPN
E--KI---KQAAIARAVNWIASMQCKPGGWAAFDLDNDQDW---LNPYGDLKAM-IDPNTADVTARVVEMLGAC-D------LSIDSDNLERSLTYLLRE
QETEGCWFGRWGVNYIYGTSGVLSALALIDPQRH-KLSIERGAAWLLGCQN-DGGWGETCRSYDDLKGKG--DSTASQTAWALIGLLAAGE--TAVKAIE
QGIGYLMATQQPDGTWFEANFTGGFPCYFYLKYHLYQQYFPLIALGRYQAAIKES--
>tr|A0A0C2LJ93|A0A0C2LJ93_9CYAN Scaffold_5, whole genome shotgun sequence OS=Tolypothrix campylonemoides VB511288 GN=SD81_26385 PE=4 SV=1
---------------------------------------------------------------------------------------------VKEAIAA
SQNYLLSIQYPDGYWWAELESNVTITAEVVLLHKIWGTDRERP----LHKVEAYLRSQQRDHGGWELFYGDGGELSTSVEAYMALKLLGVPQTDP---AM
VKARKFILERGGISKTRIFTKLHLALIGCYNWRGIPSLPPWVMLLPSNFVFNIYEMSSWARSSTVPLLIVFDRKPVFLT-DPI---TDELYAEGVEVRYE
----------L----DLF--ITLDDTF-KL----AETL-LVPFREEGIQAAERWILEREATGDWGGIIPAMLLLALRALYDAAD--PIVERGLRAVDNFA
IETA-TYRIQPC-ISPVWDTAWAMRALVASGL--ADHPAVVRGGEWLLSKQIL--DYGDWAINRTGKPGAWAFEFENRFYPDVDDTAVVVMALNEVKLPN
E--KL---KQAAIARALNWITSMQCQPGGWAAFDMDNDQDW---INPYADLKAM-IDPNTADVTARVLEMLGEC-N------LSIDARNLERAISYLKAE
QKTEGCWFGRWGVNYIYGTSGVLCALSLIAPEKT-RLSIEQGAAWLVGCQN-DGGWGETCRSYDDLKGQG--ASTASQTAWAILGLIAAGQ--TAKVALE
RGIGYLLETQRSDGTWDESEFTGGFPSHFYLKYHLYQQYFPLLALGRYQAISELW--
>tr|K9WPT3|K9WPT3_9CYAN Squalene-hopene cyclase OS=Microcoleus sp. PCC 7113 GN=Mic7113_5949 PE=4 SV=1
---------------------------------------------------------------------------------------------LAEAIAA
TQNYLLSIQNPAGYWWAELESNVTITAEAVLLHKIWGTDTERP----LHKVEHYLRSQQREHGGWELFYGDGGELSTSVEAYMALKLLGVSETDP---AM
LRAKTFILQRGGISRSRIFTKIHLALIGCYSWQGVPSLPPWVMLLPEQFPFNIYEMSSWARSSTVPLLIVLDRKPVFQV-NPI---TDELYTEGREARFD
----------L----DVF--LVLDNAF-KF----AESL-LVPFRQEGIKAAEKWILEREATGDWGGIIPAMLLLALRCLYDAAD--PIVHRGLKAVDHFA
IETE-SYCVQPC-VSPVWDTAWVIRALMDSGF--SKHPAIVGAGEWLLSKQIL--DYGDWAVNKQGKPGAWAFEFENRFYPDVDDSAVVVMALHQVQLPN
E--RL---KQAAIARTVNWIASMQCQAGGWAAFDLNNNQDW---LNPYGDLKAM-IDPNTADVTARVLEMLGWC-N------LSIDANQTARAIDYLIRE
QEADGSWFGRWGVNYIYGTSGALSALALIAPQTH-SRHIERGAAWLAGCQN-DGGWGETCRSYDNLKGQG--TSTASQTAWALIGLMAAGE--TASEAIE
RGVNYLLNTQRSDGTWNESEFTGGFPSHFYLKYHLYQQYFPLMALGRHQTLLTQQ--
>tr|A0A0D6KNZ0|A0A0D6KNZ0_9CYAN Squalene-hopene cyclase OS=Tolypothrix sp. PCC 7601 GN=FDUTEX481_08228 PE=4 SV=1
---------------------------------------------------------------------------------------------VAEAIAK
SQQYLLSIQNPAGYWWAELESNVTITAEAVLLHKIWGTDSTRP----LHKVENYLRSQQREHGGWELYFGDGGELSTTVEAYMALKLLGVSATDP---AM
LKAKAFILQRGGISKTRIFTKLHLALIGCYDWRGIPSLPPWIMLLPNSFPVNIYEMSSWARSSTVPLLIVCDRKPIFQI-DPI---SDELYVEGRDVQWE
----------L----DIF--ITLDQGF-KF----AESL-WVPFRKEGIKAAEKWVLEREATGDWGGIIPAMLLLALRCLYDPAD--PIVERGLKAVDNFA
IETA-SYCVQPC-VSPVWDTAWAIRALIDSGY--ANDSAIVKAGEWLIDKQIL--DYGDWTINRQGKPGAWAFEFDNRFYPDVDDSAVVVMALHQAKLPN
E--KL---KQAAIARALNWIASMQCKPGGWAAFDIDNDQDW---LNPYGDLKAM-IDPNTADVTARVLEMLGAS-N------LSINQQNFERAIAYLLRE
QEQEGCWFGRWGVNYIYGTSGVLSALALVAPKTQ-QQSIERGGAWLVGCQN-DGGWGETCRTYNDLKGQG--TSTASQTAWALIGLIAAGE--TAHNAIE
QGINYLLTTQKPDGTWYESYFTGGFPCHFYLKYHLYQQYFPLIALGRYRAVLGIG--
>tr|F4Y2C6|F4Y2C6_9CYAN Squalene-hopene cyclase OS=Moorea producens 3L GN=LYNGBM3L_69370 PE=4 SV=1
---------------------------------------------------------------------------------------------VTGAIAN
SQSYLLAQQYPDGYWWAELESNVTITAEIVLLHKIWGTDKQRP----LHKAEAYLRSQQQKHGGWELFYGDGGHLSCSVEAYMALRLLGVPASDS---AL
VRARDFILRRGGISKTRIFTKFHLALIGCYSWRGIPSIPPWIMLFPEWFPFTIYEMSSWARGSTVPLLIVFDQKPVFEI-EPI---NDELYTEGADVKFE
----------L----DLF--VLLDDGF-KL----AEDW-LVPFRKQGLAAAEKWVLEREATGDWGGIIPAMLLLALRCLYDLAD--PIVQRGLEAIDRFA
IETP-SYRVQAC-VSPVWDTAWVLRAMVESGL--EDHPALVRGGEWLLQQQIL--DYGDWVVNPQGKPGGWAFEFQNRFYPDLDDSPVVIMALNSLKLPN
Q--KL---KQAAMARGLAWIASMQCNQGGWAAFDINNNQHW---LNPYADLKAM-IDPNTADVTARVLEMLGSC-N------LSIESQKLENAIAFLIQE
QEADGSWFGRWGVNYIYGTSSALSALSKIAPHTH-QRSIERGAAWLVKCQN-NGGWGETCLSYDDLKGLG--ISTASQTAWALIGLMAAGE--TAMDAIE
MGVNYLVSTQQPDGSWDETEFTGGFPSHFYLKYHFYQQYFPLLALGRYQMSVAS---
>tr|K9T630|K9T630_9CYAN Squalene-hopene cyclase OS=Pleurocapsa sp. PCC 7327 GN=Ple7327_2716 PE=4 SV=1
---------------------------------------------------------------------------------------------VSEAIAA
SQNYLLSIQDPQGYWWAELESNVTITSEVVLLHKIWGTDRDRP----LHKVEAYLRAEQREHGGWELFCGDGGDLSTSVEAYMALRLLGVPQSDP---AL
LRAKDFILKRGGISKTRIFTKIHLALIGCYDWRGVPAIPPWIMLFPENFPFTIYEMSSWARSSTVPLLIVFDRKPVFVT-EPI---TDELYAEGIEARYE
----------L----DVF--VWLDKAF-KL----AEDL-LVPWRQAGVDAAEKWILEREVSGDWGGIIPAMLLLSLRVLYDTAD--PVVERGLKAIDNFA
IATE-TYRVQPC-VSPVWDTAWTLRALVESGI--ADNPALARGGEWLLGKQIL--SYGDWAVNKQGKPGGWAFEFENRFYPDLDDSAVVVMALNGLKLPN
E--SL---KQAAIKRCVAWMATMQCRSGGWAAFDVDNDQNW---LNPYADLKAM-IDPNTADVTARVLEMLGSG-N------LMMDSDRVERATAFLEKQ
QEADGSWFGRWGVNYIYGTSGAISALAVIAPRTH-QRQLQGGAAWLVGCQN-DGGWGETCRSYDDLKGKG--VSTASQTAWALIGLLAAGQ--TEQRAIE
SGINYLVAVQRSDGTWDECEFTGGFPGHFYLKYHLYQQYFPLIALSRYQRLQPYI--
>tr|Q3M418|Q3M418_ANAVT Terpene synthase OS=Anabaena variabilis (strain ATCC 29413 / PCC 7937) GN=Ava_4671 PE=4 SV=1
---------------------------------------------------------------------------------------------IAEAIAA
SQKYLLSLQNPTGYWWAELESNVTITAEVVLLHKIWGTDKTRP----LHKIEAYLRSQQKQHGGWELFYGDGGELSTSVEAYMALKLLGVPATDP---AM
IQARDFILQRGGISKTRIFTKFHLALIGCYNWRGLPSLPAWVMLLPNQFPVNIYEMSSWARSSTVPLLIVFDQKPVYQV-NPI---TDELYAEGVEVRYE
----------L----DLF--LTLDEGF-KL----AESF-FIPFREEGIKAAEKWIIEREATGDWGGIIPAMLMLALRVLYATND--PIVERGLQAIDNFA
IETA-CYRVQPC-VSPVWDTAWVIRALIDSGM--ADHPAIVKAGEWLLQKQIF--DYGDWNVNRQGQPGAWAFEFDNRFYPDVDDTAVVVMALHAAKLPH
E--QL---KQKACDRALQWVASMQCKPGGWAAFDIDNDQDW---LNPYGDLKAM-IDPNTADVTARVIEMLGAC-N------LSIDSHDLERALTYLLNE
QEAEGCWFGRWGVNYIYGTSGVLCALALINPQKY-QRHIQQGATWLVGCQN-DGGWGETCFSYNDLKGQG--DSTPSQTAWALIGLIAAGE--TAHDVIE
RGINHLVSTQQPDGSWFEAYFTGGFPCHFYLKYHYYQQYFPLIALGRYQAINPL---
>tr|E0UII0|E0UII0_CYAP2 Squalene/oxidosqualene cyclase OS=Cyanothece sp. (strain PCC 7822) GN=Cyan7822_0123 PE=4 SV=1
---------------------------------------------------------------------------------------------VKEAIAA
SQQYLLSIQYPEGYWWAELESNVTITAEAVLLHKIWGTDTTRP----LHKVETYLRRQQREHGGWELFYGDGGDLSTSVEAYMALRLLGVSASDP---AL
VRAKAFILSRGGISKSRIFTKMHLALIGCYDWRGVPSIPPWIMLLPENFPFTIYEMSSWARGSTVPLLIVFDKKPVYQC-G-I---TDELYSEGINVRYD
----------L----DVF--VWLDGVF-KF----AETN-LIPFRNESLKAAERWVLEREDTGDWGGIIPAMLLLALRALYEVND--PIVHRGFKSVDNFA
IETE-TYHVQPC-ISPVWDTAWVLRALVESGL--KDEPVLVKGAQWLLDKQIL--DYGDWAVNKEGTPGGWAFEFDNRWYPDLDDSAVVVMALEQVKMPD
E--QL---KYGAMRRCVRWMATMQCKAGGWGAFDVNNDQNW---LNPYADLKAM-IDPNTADVTARVLEMLGTC-E------LSMDHDRVKRAIAYLEQE
QEADGSWFGRWGVNYIYGTSGALSALAAIAPVTH-QAQIEKGAAWLVGCQN-DGGWGETCFSYNNLRGKG--DSTASQTAWGLIGLLAAGE--TAKTALE
RGVNYLLATQRPDGTWDESYFTGGFPCHFYLKYHLYLQYFPLIALSRYQRLLGFN--
>tr|A0A0C1RJW6|A0A0C1RJW6_9CYAN Squalene cyclase OS=Tolypothrix bouteillei VB521301 GN=DA73_0212235 PE=4 SV=1
---------------------------------------------------------------------------------------------IQKAIAA
SQNYLLSLQYPDGYWWAELESNVTITAEVVLLHKIWGTDSTRA----LHKVEAYLRAQQRDHGGWELFYGDGGELSTSVEAYMALKLLGVSETDP---AM
VKARKFILEHGGISRTRIFTKLHLALIGCYDWRGIPSLPPWVMLLPSNFLFNIYEMSSWARSSTVPLLIVFDRKPVFVT-NPI---SDELYTEGVEAKFE
----------L----DIF--ILLDNAF-KL----AETL-LVPFREEGIQAAERWTLERETTGDWGGIIPAMLLLALRTLYDAAD--PIVQRGLRAVDNFV
IETE-TYTVQPC-VSPVWDTAWVMRSLVASGL--ADHPAVVRAGEWLLNKQIL--DYGDWSVNRQGKPGAWAFEFDNRFYPDVDDTAVVVMALDAVKLPN
E--KL---KQAAIARAVQWIASMQCRAGGWAAFDLDNDQDW---INPYGDLKAM-IDPNTADVTARVLEMLGGC-N------LFIEDDKLERAITYLLRE
QEPEGCWFGRWGVNYIYGTSGVLAALALIAPERT-QVRIEKGAAWLVGCQN-DGGWGETCRSYDDLKGKG--TSTASQTAWAVLGLIAAGE--TARTAIQ
RGIHYLTETQKPDGTWYESEFTGGFPGHFYLKYHLYQQVFPLLALSKYQEVSHLF--
>tr|K9PE31|K9PE31_9CYAN Squalene-hopene cyclase OS=Calothrix sp. PCC 7507 GN=Cal7507_0308 PE=4 SV=1
---------------------------------------------------------------------------------------------TAAAIAA
SQQYLLSIQNPAGYWWAELESNVTITAETVLLHKIWGTDITRP----LHKVEAYLRQQQRNHGGWELFYGDGGELSTSVEAYMALRLLGVPNTDP---AM
IQARTFILQRGGISKTRIFTKLHLALIGCYDWRGLPSLPAWVMLLPPAFPFNIYEMSSWARSSTVPLLIVFDRKPVFIT-DPI---NDELYAEGVDVQFA
----------L----DLF--ITLDHGF-KL----AESL-LLPFRQEGINAAEKWILEREATGDWGGIIPAMLLLALRCLYDASD--PIVERGLKAVDNFA
IETE-SYRVQPC-VSPVWDTAWVIRALVDSGF--TDHPAIVKAGEWLLDQQIL--DYGDWNVNRQGKPGAWAFEFDNRFYPDVDDSAVVVMALHQAKLPN
E--KL---KHAAIARAVNWIASMQCKPGGWAAFDLDNDQDW---LNPYGDLKAM-IDPNTADVTARVLEMLGAG-N------LAIDPDNLARAIAYIINE
QEPEGCWFGRWGVNYIYGTSGVLSALALIDPLKY-QLNIKRGAAWLVSCQN-DGGWGETCRSYDDLKGQG--TSTASQTAWALIGLIAAGE--TADHTLE
KGINFLLTTQQPDGTWYEADFTGGFPSHFYLKYHMYQQYFPLIALGRYQSVLDNG--
>tr|B0C3I2|B0C3I2_ACAM1 Squalene-hopene cyclase OS=Acaryochloris marina (strain MBIC 11017) GN=shc PE=4 SV=1
---------------------------------------------------------------------------------------------LEAAIAA
SQSYLLTQQDETGYWWAELESNVSITSEVVLLHKIWGTDRSRP----LEKVETYLRSQQRDHGGWELYFDDGGEISVSVEAYMALKLLGVPMEDP---AM
VRARQFILEHGGISRTRVFTKLHLALIGCYEWRGIPSLPPWVMLLPEQFPFTIYEMSSWARGSTVPLLIVMDREPVYAV-EAF---NDELYVEGRHAQFD
----------L----DAF--IYLDGLF-KF----AEST-LVPFREEGIRAAERWILEREATGDWGGIIPAMLLLGLKALYDVHD--PIIERGMAALDAFA
LETE-QYWIQPC-ISPVWDTALVVRGLAESGL--ADHPALVKAGEWLLNKQIL--DYGDWSVNPGGLPGGWAFEFDNRFYPDVDDTAVVVMALNEVQLPD
E--QA---KDAAIARAVNWIATMQCRPGGWAAFDINNDQDW---LNPYGDLKAM-IDPNTADVTARVLEMIGRC-H------QTTGKNSVDRALRYLRTE
QEPEGCWFGRWGVNYIYGTSGVLAALALIDPQGW-QSQIQQAAAWLVSCQN-DGGWGETCASYDNLKGQG--PSTASQTAWAIMGLLSAGE--TAEAAIE
RGVNYLTTTQKMDGTWDEDYFTGGFPGHFYLKYHLYQQHFPLTALGRYQAMLQQK--
>tr|B7KE21|B7KE21_CYAP7 Squalene/oxidosqualene cyclase OS=Cyanothece sp. (strain PCC 7424) GN=PCC7424_3320 PE=4 SV=1
---------------------------------------------------------------------------------------------VKDAIAA
SQDYLMSIQYPEGYWWAELESNVTITAEVVLLHKIWGTDKTRP----LHKVETYLRRQQREHGGWELFYGDGGDLSTSVEAYMALRLLGVSIDDP---AL
IRGREFILKRGGISKSRIFTKLHLALIGCYDWRGIPSIPPWIMLLPENFPFTIYEMSSWARSSTVPLLIVFDKKPVYCC-DPI---NDELYSEGIEVKYD
----------L----DIF--VWLDGVF-KF----AQDY-LVPLRQESLQAAERWVLEREDSGDWGGIIPAMLLLALRALYEAVD--PIVHRGLQSVDNFA
IETE-TYHVQPC-ISPVWDTAWAIRALVESGL--KDDPRLVKGAQWLLDKQIL--DYGDWAVNKQGTPGGWAFEFDNRWYPDLDDSAVVVMALDQVKMPN
E--DL---KNGAIRRCVRWMATMQCKDGGWGAFDLDNDQNW---LNPYADLKAM-IDPNTSDVTARVLEMLGTC-G------LIMDSNRVQKAIAYLEKE
QEPDGSWFGRWGVNYIYGTSGVLSALAVIAPETH-QKELKKGAAWLVGCQN-DGGWGETCFSYNDLKGKG--DSTASQTAWGLIGLLAAGE--TFKTAIE
RGVNYLLKTQREDGTWDENYFTGGFPCHFYLKYHLYLQYFPLIALSRYQRLLT----
>tr|A0A0C2QU55|A0A0C2QU55_9CYAN Scaffold_8, whole genome shotgun sequence OS=Scytonema tolypothrichoides VB-61278 GN=SD80_13730 PE=4 SV=1
---------------------------------------------------------------------------------------------SSEAIAK
NQNYLLSIQHPDGYWWAELESNVTITAEVVLLHKIWGTDRERP----LHKVEAYLRSQQRDHGGWELFYGDGGELSTSVEAYMALKLLGVAETDA---AM
VKAREFILQRGGISKARIFTKLHLALIGCYSWQGIPSLPPWVMLLPDNFLFNIYEMSSWARSSTVPLLIVIDRKPVFVT-DPI---TDELYAEGIEARYE
----------L----DLF--ITLDNAF-KL----AETL-LVPFREEGIQAAERWILEREVTGDWGGIIPAMLLLALRALYNPAD--PIVERGLRAVDNFA
IETA-TYTVQPC-ISPVWDTAWVMRALVESGL--ADHPAVVRAGEWLLSKQIL--DYGDWAINKKGKPGAWAFEFDNRFYPDVDDTAVVVMALNEVKLPN
E--KL---KEAAIARAVNWIASMQCQPGGWAAFDLDNNQEW---LNPYGDLKAM-IDPNTADVTARVLEMLGCG-N------LSIETHNLERAITYLIRE
QESEGCWFGRWGVNYIYGTSGVLSALSLIAPDNM-QVSIERGAAWLVGCQN-DGGWGETCRSYNDLKGQG--PSTASQTAWAIIGLIAAGQ--TAKLAIE
RGITYLLETQQSDGTWYEADFTGGFPCHFYLKYHLYQQYFPLLALGRYQGISKLW--
>tr|K9Q5X1|K9Q5X1_9NOSO Squalene-hopene cyclase OS=Nostoc sp. PCC 7107 GN=Nos7107_0414 PE=4 SV=1
---------------------------------------------------------------------------------------------VADAIAA
SQAYLLSMQYPAGYWWAELESNVTITAEVVLLHKIWGTDKTRP----LHKMENYLRSQQRQHGGWELFYDDGGEISTSVEAYMALRLLGVPATDP---AL
IRARDFILQRGGISKTRIFTKLHLALIGCYSWRGIPSLPPWIMLLPPAFPVNIYEMSSWARSSTVPLLIVCDSKPIYQL-DQI---NDELYAEGLNVQYE
----------L----DLF--LTLDQGF-KL----AESL-LVPFRQEGIKAAEKWILEREATGDWGGIIPAMLMLALKCLYSQND--PIVERGFQAIDNFA
IETE-NYCIQPC-ISPVWDTAWVIRALIDSGF--ADDPAIVKAGEWLLQKQIL--DYGDWTVNRQGKPGAWAFEFDNRFYPDVDDTAVVVMALHPAKLPN
E--SL---KQAAIARALNWVASMQCRPGGWAAFDLDNDQEW---LNPYGDLKAM-IDPNTADVTARVIEMLGAC-D------LSIDSRNLERALSYLLAE
QEPEGCWFGRWGVNYIYGTSGVLSALALINPQKY-QPNIDKGAAWLVGCQN-DGGWGETCRTYNDLKGQG--RSTASQTAWALIGLIAAGE--TAMSAIE
RGINYLVSTQKPDGTWFEADFTGGFPCHFYLKYHLYQQYFPLIALGRYHNIK-----
>tr|K9RTK2|K9RTK2_SYNP3 Squalene-hopene cyclase OS=Synechococcus sp. (strain ATCC 27167 / PCC 6312) GN=Syn6312_1461 PE=4 SV=1
---------------------------------------------------------------------------------------------LDAAIQA
SQNYLLSQQYKDGYWCSELESNCTMTAEAVLLHKIWGTDKNRP----LAKAKTFLQSQQREHGGWELFYGDGGDLSTSVETYTALRLLGVAANDP---DM
VRAKDFILAKGGISKTRIFTKLHLALIGCYDWRGIPSLPPWVMLLPEWGPFTIYEMSSWARGSTVPLLIVMDRKPVYVT-NPV---NDELYLEGRAVNWS
----------L----DLF--LELDNVF-KF----CEEW-LTPLREEGLQAAEKWVLEREASGDWGGIIPAMLLLALRALYNAHD--PIVQRGLESVDRFA
IETE-WYRVQPC-VSPVWDTALVMRALVDSGL--EDHPALVTGGNWLIEKQIL--DYGDWAVNKIGKPGAWAFEFENRFYPDVDDTAVVVMALEAVKLPD
E--KL---KQEAMQRAVDWIATMQCKPGGWAAFDIDNDQDW---LNPYGDLRAM-IDPNTADVTARVLEMIGRT-D------MTTGEASVDKALAYLRTE
QEPEGCWYGRWGVNYVYGTSGVLAALALVAPPYD-RWRLRRAVKWLVSVQN-DGGWGETCRSYNDLKGKG--ESTPSQTAWALIGLLAAGE--VATDAIR
RGVEHLIATQRADGTWNEDYFTGGFPCHFYLKYHLYQQHFPLTALGRYRQYQQTV--
>tr|K9QUQ8|K9QUQ8_NOSS7 Squalene-hopene cyclase OS=Nostoc sp. (strain ATCC 29411 / PCC 7524) GN=Nos7524_3073 PE=4 SV=1
---------------------------------------------------------------------------------------------LAEAIAA
SQQYLLSLQNPAGYWWAELESNVTITAEVVLLHKIWGTDKTRP----LHKVAAYLRSQQRQHGGWELFYDDGGELSTSVEAYMALRLLGVPATDP---DM
IRARDFIIQRGGISKTRIFTKFHLALLGCYDWRGLPSLPAWVMLLPKEFPVNIYEMSSWARSSTVPLLIVFDRKPVFVT-KPI---NDELYAEGREVRWE
----------L----DLF--LTLDEGF-KF----AESL-FIPFRAEGIKAAEQWILEREATGDWGGIIPAMLMLALRCLYESSD--PIVERGLQAIDNFA
IETE-SYRVQPC-VSPVWDTAWVMRAFVDSGM--SDHPAIVKAGEWLLQKQIL--DYGDWTVNRQGKPGAWAFEFDNRFYPDVDDTAVVVMALYAAKLPN
E--LL---KQKACDRAIQWVASMQCKPGGWAAFDIDNDQDW---LNPYGDLKAM-IDPNTADVTARVLEMLGIC-N------LSIAPHNLERALNYLLNE
QELEGCWFGRWGVNYIYGTSGVLSALAVIAPQKY-RRNIEQGAAWLVSCQN-DGGWGETCRSYNDLKGQG--RSTASQTAWALIGLIAAGE--TAHEAIE
KGISYLVSTQKPDGSWFEADFTGGFPCHFYLKYHFYQQYFPLIALGKYQGMGSRE--
>tr|K9WWU1|K9WWU1_9NOST Squalene-hopene cyclase OS=Cylindrospermum stagnale PCC 7417 GN=Cylst_2445 PE=4 SV=1
---------------------------------------------------------------------------------------------VETAIAA
SQNFLLSLQNTDGYWWAELESNVTITAEVVLLHKIWGTDKTRS----LDKVATYLRSQQRQHGGWEMFYGDGGDLSTSVEAYMALKLLGVPATDP---AM
IKAQAFIVGRGGISKTRIFTKLYLALIGCYNWRGLPSLPPWVMLVPNDFPVNIYSMSSWARSSTVPLLIVLDRKPVYLT-DPI---SDELYAESINVQFE
----------L----DLF--ITLDHGF-KL----AESL-LVFFREEGIKAAEKWILEREATGDWGGIIPAMLLLALRCLYDVTD--PIVERGLQAVDHFA
IETE-HYRIQPC-VSPVWDTAWVMRALIDSGL--ADHPAVVRGGEWLLQKQIL--DYGDWAVNRQGKPGAWAFEFENRFYPDVDDSAVVVMALQAAKLPN
E--KL---KQNAIARALNWIASMQCKPGGWAAFDLDNDQDW---LNPYADLKAM-IDPNTADVTARVLEMLGLC-H------LSIDTYNLERALAYIISE
QETEGCWFGRWGVNYIYGTSGVLSALALINPQKH-KLSIERGAAWLAKCQN-DGGWGETCRSYDDLKGQG--CSTASQTAWALIGLIAAGE--TAVDIIE
KGISYLLATQQSNGTWDEAEFTGGFPGHFYLKYHLYQQYFPLIALGRYQAMIKET--
>tr|A0A098TKE2|A0A098TKE2_9CHRO Squalene cyclase OS=Neosynechococcus sphagnicola sy1 GN=DO97_05255 PE=4 SV=1
---------------------------------------------------------------------------------------------LDTAIAL
SQNYLLATQNDAGYWWAELESNVTITAEAVLVHKIWGTDKNRP----LHKVEAYLRSQQRNHGGWELFYGDGGELSTTVEAYMAMRLLGVSATDP---AL
LRAKEFVLARGGIRKTRIFTKMHLALIGCYGWEGIPSIPPWVMLLPNQPIFTIYEMSSWARGSTVPLLIVFDKKPIYTV-DPV---TEELYLEPPRRRFE
----------I----DIF--VTLDDLF-KL----GEKL-LVPFREQGLKAAEKWVLEREATGDWGGIIPAMLLLALRCLYDSAD--PIVERGLRAVDNFA
IETT-TYRVQPC-ISPVWDTALVMRALVDSGM--ADHPALVKGGNWLIEKQIL--DYGDWQINLHGQPGAWAFEFENRFYPDVDDTAVVVMALSAVQLPN
E--QL---QQQAIARAVNWVASMQCRDGGWAAFDLDNNADW---LNPYGDLKAM-IDPNTADVTARVLEMVGRLTVPD--LELALTPYNLDRALNYLTQE
QESEGCWFGRWGVNYIYGTSGVLAALALIAPQSH-HRQIQRGAAWLASCQN-DGGWGETCRSYDDLKGQG--CSTASQTAWALIGLLAAGD--TNRDALD
RGINYLLNSQRTDGTWDESDFTGGFPGHFYLKYHLYQQHFPLTALGRYRACFAAS--
>tr|K9ZMR9|K9ZMR9_ANACC Squalene-hopene cyclase OS=Anabaena cylindrica (strain ATCC 27899 / PCC 7122) GN=Anacy_5203 PE=4 SV=1
---------------------------------------------------------------------------------------------IAEAIKA
SQKHLLAIQKPDGYWWAELESNVTITAEAVLLHKIWGTDKTRP----LHKVETYLRSQQREHGGWELFYGDGGELSTTVEAYMALRLLGVPANDP---AL
IKAKSWILEKGGISKTRIFTKLHLALIGCYNWRGLPSLPSWVMLLPDNFPFNIYELSSWARSSTVPLLIVFDRKPIFKI-DQI---NDELYTEGVKVKWE
----------L----DIF--NILDNGF-KL----AESF-FVPFRNEGIKAAEKWILEREATGDWGGIIPAMLLLALKCLYDAND--PIIYRGLKAVDNFA
IETE-SYCVQPC-VSPVWDTAWAIRALIDSGF--PDDPAIIKAGEWLLEKQIL--DYGDWSVNKQGKPGAWAFEFDNRFYPDVDDSAVVVMALHQTKLPN
E--EL---KKQAINRALNWIASMQCQPGGWAAFDIDNNQDW---LNPYGDLKAM-IDPNTADVTARVLEMLGAC-N------LSIPSDKLEKSLDYLLNE
QEKEGCWFGRWGVNYIYGTSGVLSALALINPQKY-RSEIEQGAAWLVKVQN-DGGWGETCFSYNDLKGKG--DSTASQTAWGLIGLIAAGE--TPFDSIE
RGINYLLETQRSDGTWDESYFTGGFPCHFYLKYHLYQQYFPLIALGRYQGIKG----
>tr|G6FPH9|G6FPH9_9CYAN Squalene-hopene cyclase OS=Fischerella sp. JSC-11 GN=FJSC11DRAFT_0759 PE=4 SV=1
---------------------------------------------------------------------------------------------LPDAIAA
SQNYLLSIQNPQGYWWAELESNVTITAEVVLLHKIWGTDKSRP----LEKVEAYLRSQQREHGGWELFYDDGGELSTSVEAYMALRLLGVPPTDS---AM
LKARKFILERGGISRTRVFTKLHLALIGCYSWQGIPSLPPWVMLLPENFFFNIYEMSSWARSSTVPLLIVCDRKPVFAI-DPI---NNELYAEGIEVKYE
----------L----DIF--LTLDSGF-KL----AENL-LVPFRTEGIKAAEKWILEREATGDWGGIIPAMLLLALRCLYDAAD--PIVERGLQAVDNFA
IETA-TYRVQPC-VSPVWDTAWAIRALVDSGL--ADHPAVVRSAEWLLNKQIL--DYGDWAVNRQGKPGAWAFEFDNRFYPDVDDTAVVVMALNQVKLPN
Q--KL---KHQAMRRAVEWVASMQCKAGGWAAFDLDNDQDW---LNPYGDLKAM-IDPNTADVTARVLEMLGSC-H------LSIDRYNQQRAIQYLLNE
QEPEGCWFGRWGVNYIYGTSGALAALSLVAPQTH-RYNIEQGAAWLISCQN-DGGWGETCRSYDDLKGKG--RSTASQTAWALIGLMAAGR--TAKPAIE
RGIDYLLVTQLPNGSWDEADFTGGFPSHFYLKYHLYQQYFPLIALGQYQKLFA----
>tr|K7W6P5|K7W6P5_9NOST Squalene-hopene cyclase OS=Anabaena sp. 90 GN=ANA_C12765 PE=4 SV=1
---------------------------------------------------------------------------------------------VVDAIAA
SQKHLLSIQNPDGYWWAELESNVTITSEAVLLHKIWGTEKTRP----LHKVENYLRSQQREHGGWELFYGDGGDLNTTVEAYMALRLLGVPATDT---AL
LKAKSLILAKGGISKTRIFTKLHLALIDCYNWRGLPSLPPWVMLLPDNFFFNIYELSSWARSSTVPLLIVFDRKPIFNI-DQI---NDELYAEGVNVCWE
----------L----DIF--NILDDGF-KL----AESI-FVPFRNEGIKAAEKWILEREVTGDWGGIIPAMLLLALKCLYDAND--PVIERGLKAVDNFA
IETE-SYCVQPC-VSPVWDTAWVIRALIDSGF--ANDPAIVKAGEWLIEKQIL--DYGDWNVNKQGKPGAWAFEFENRFYPDVDDSAVVVMALHQAKLRN
E--EL---KKQAIDRALNWIATMQCKPGGWAAFDLDNDQEW---LNPYGDLKAM-IDPNTADVTARVLEMLGAC-N------LSIQPDNLEKSLDYLLKE
QEIEGCWFGRWGVNYIYGTSGVLSALALINPLKY-ARDINQGAAWLVKVQN-DGGWGETCFSYNDLKGKG--DSTASQTAWALIGLIAAGE--TAIDSIE
KGINYLLETQKLDGTWDEEYFTGGFPCHFYLKYHLYQQYFPLMALGRYQAKCSS---
>tr|B7JUY9|B7JUY9_CYAP8 Squalene/oxidosqualene cyclase OS=Cyanothece sp. (strain PCC 8801) GN=PCC8801_2842 PE=4 SV=1
---------------------------------------------------------------------------------------------LTKAIIA
SQNYIMSRQYPEGYWWGELESNITLTAETILLHKIWKTDKTRP----FHKVETYLRRQQNEQGGWELFYGDGGELSTSVEAYMALRLLGVTPEDP---AL
IRAKDFILSQGGISKTRIFTKFHLALIGCYDWKGIPSIPPWIMLFPDNFPFTIYEMSSWARESTVPLLIVFDKKPIFEI-EPF---NDELYAEGVEVKYA
----------L----DIF--LGLDKLF-KW----TEKN-LVPFHKKSLQAAERWMLNHQESGDWGGIMPPMVLIAFKVLYDVAD--PSVQRGFEAIDRFS
IEEE-TYRVQAC-VSPVWDTAWVIRALVDSGL--KDHPSLVKAGEWLLDKQIL--EYGDWAINKQGKPGGWAFEFINRFYPDLDDSAVVVMALNGIKLPD
E--NC---KKAAINRCLEWMATMQCKPGGWAAFDVDNDQAW---INPYGDLKAM-IDPNTADVTARVLEMVGSC-G------LKMDENRVQKALFYLEKE
QESDGSWFGRWGVNYIYGTSGVLSALAVIAPNTH-KPQMEKAVNWLISCQN-DGGWGETCWSYNDLKGTG--VSTASQTAWALIGLLDAGE--LATDAIK
RGINYLLDTQTPDGTWEEAEFTGGFPCHFYIRYHLYRHYFPLIALGRYWKIGLKN--
>tr|A0A0C1XKF5|A0A0C1XKF5_9CYAN Squalene cyclase OS=Hassallia byssoidea VB512170 GN=PI95_29195 PE=4 SV=1
---------------------------------------------------------------------------------------------VTEAIAK
SQNHLLSIQNPAGYWWAELESNVTITAEVVLLHKIWGTDSQRP----LHKVETYLRSQQRQHGGWELFYGDGGELSTSVEAYMALRLLGVSASDP---AM
RKARDFILQRGGISKTRIFTKFHLALIGCYKWRGLPSIPPAIMLLPDAFPFNIYEMSSWARSSTVPLLIVFDDKPIYQV-DSI---ANELYVEGADIQFE
----------L----DLF--ITLDNAF-KL----AENL-LMPLRSEGIKAAEKWILEREATGDWGGIIPAMLMLALKSLYDVND--PIVVRGLQALDNFA
IETE-SYRIQPC-VSPIWDTAWAIRALIESGL--GDHPAIVKAGEFLLDKQIL--DYGDWAVNHQGKPGAWAFEFENRFYPDVDDSAVVVMALQIAKLPN
E--KL---KQQAIARGINWIASMQCQAGGWAAFDLNNNQDW---LNPYGDLKAM-IDPNTADVTARVLEMLGEC-K------QSIDTQSFEKAIAYLINE
QEPDGSWFGRWGVNYIYGTSGVLSAFALVAPQTH-QNSISRGATWLLKCQN-DGGWGETCRSYNDLKGQG--KSTASQTAWAIIGLIAAGQ--TALPAIE
KGINYLLATQQSDGTWDESEFTGGFPGHFYLKYHLYQQYFPLIALGRYQNL------
>tr|U5DJB0|U5DJB0_9CHRO Squalene-hopene cyclase OS=Rubidibacter lacunae KORDI 51-2 GN=KR51_00016320 PE=4 SV=1
---------------------------------------------------------------------------------------------LEEAVAA
SQRYLLSQQYPEGYWWAELEANVTVTVEVLLLHKIWRTDRLRP----LHKIETYLRQQQCESGGWEVFYGDGGDLSTSVEAYLGLRLLGVPAGDP---AL
VKARTFILERGGISKTRIFTKFQLALVDCYNWRGLPSIPPWIVFCHPPFPFSIYEMSSWARCSTVPLAIVFDKKPVYPV-EPV---KDELFAEGSAVRYE
----------L----DAF--VWLDDAF-KF----AEDW-LVPLREEGLKAAERWIVEREATGDWGGIIPAMVMLALRSLYAVDD--PIVDRGFQAIDNFV
LEDD-VYRVQSC-VSPVWDTAWVVRALVDSGM--ADAPEVVAAGRWLLERQIL--DYGDWRVNPQGEPGGWAFVFVNRYYPDIDDTAVVVIALEQLCLPE
E--AL---KRQAIARATQWIATMQCRAGGWAAYDVDNDSDW---LNPYSDLKAT-IDPNTADVTARVLEMVGYLDPQ---QP-GIARERCDRALDYLLDE
QESEGCWFGRWGVNYIYGTSGALSALALVAPQRA-RNAIERGAAWLVGVQN-DGGWGETCRSYEDLKGKG--VSTASQTAWALIGLLAAGD--TAQQFLA
RGVEYLLGTQLENGRWEEAEFTGGFPGHFYIRYHYYYQYFPLVALGRYRQFLAER--
>tr|T2JBH3|T2JBH3_CROWT Squalene--hopene cyclase OS=Crocosphaera watsonii WH 0401 GN=CWATWH0401_4248 PE=4 SV=1
---------------------------------------------------------------------------------------------LKDAITA
SQNYLLSLQYPQGYWWAELESNITLTAETVLLHKIWGTDKTRP----LHKVEAYLRQQQREHGGWELFYGDGGEISTSVEAYMALRLLGVPQDDP---AL
IRAKDFIISKGGISKTRIFTKFHLALIGCYDWKGIPSIPPWIMLFPDSFPFTIYEMASWARESTVPLIIVFNDKPVFSV-DPF---NDELYAEGLEVKYE
----------L----DIF--LGIDQVF-KF----AEQV-LVPFRKEGLKAAEKWILNHQETGDWGGIMPPMLLLAFRTLYDVND--PSVKLGFEAIDRFS
IEED-TYRLQAC-VSPIWDTAWCVRALTDSGL--EDHFSLVKAGKWLLDKQVM--EYGDWAVNKAGKPGGWAFEFTNRFYPDLDDSATVVMALNGIKLPD
E--AR---KQAAINRCLQWIETMQCKEGGWAAFDLNNDQAW---LNPYGDLKAM-IDPNTADVTARVVEMLGSC-D------LEIESDRLNKSLNYLYKE
QEKDGSWFGRWGVNYIYGTSGVLSALAVINPEKH-KTQMEQGINWLLSCQN-DGGWGETCRSYNDLKGKG--VSTPSQTAWSLIGLLDAGE--LETDAIE
RGVNYLLDTQTEEGTWEESEFTGGFPCHFYIRYHFYRHYFPLIALGRYQNLSSEF--
>tr|K9XY11|K9XY11_STAC7 Squalene-hopene cyclase OS=Stanieria cyanosphaera (strain ATCC 29371 / PCC 7437) GN=Sta7437_3936 PE=4 SV=1
---------------------------------------------------------------------------------------------LQFAIAK
SQDYLLSIQNPDGYWWAELESNVTITAEVILLHKIWGTDQTRSQ-A-LQKAETYLRSQQREHGGWELYYGDGGELSTSVEAYMALRLLGVAAQDP---AL
IKAKQFILQRGGISKTRIFTKLHLALIGCYDWRGLPSIPPWIMLLPEHFPFTIYEMSSWARGSTVPLLIVFDRKPIFVT-KII---NDELYAEGVNCRYE
----------L----DVF--LWLDDAC-KL----AENF-LVPFREEGLKAAEKWVLEREATGDWGGIIPAMLLLALRTLYEVDD--PIIQRGLAAIDNFA
IETE-SYRVQPC-VSPVWDTAWCLRALVESGL--PNHQTLVRGGQWLLDKQIL--DYGDWAVNKQGKPGGWAFEFDNRFYPDLDDSAVVVMGLAEVQLPN
E--AQ---KQSAIARGVNWMATMQCRAGGWAAFDIDNDQDW---INPYGDLKAM-IDPNTADVTARVLEMLGQY-H------LAMKADQVNRAIAYLISE
QENDGSWFGRWGVNYIYGTSGALSALAVIAPKDY-QTEIDRGATWLVSCQN-DGGWGESCRSYHDLKGKG--VSTASQTAWALIGLLAAYQ--TAQSAIE
TGINYLLATQNNDGTWYEAEFTGGFPCHFYLKYHLYQQYFPLLALGRYQKLMK----
>tr|K9SZX4|K9SZX4_9SYNE Squalene-hopene cyclase OS=Synechococcus sp. PCC 7502 GN=Syn7502_03476 PE=4 SV=1
---------------------------------------------------------------------------------------------VTEAIAK
SQAYLLSLQDSSGYWWAELESNVTITAETVLLHKIWGSEQGRN----LHKVETYLRAEQRNHGGWELFYGDGGDLSTSVEAYMALRLLGVVADDP---AL
IRAKEFILARGGITKTRIFTKMHLALIGCYNWKGLPSIPPWVILLPDAFPFNIYEMSSWARGSTVPLLIVFDRKPVYNL-NPI---NNELYSEGFAVKYQ
----------L----DIF--VNLDDLF-KI----GESL-LVPFREEGIKASEKWILEREATGDWGGIIPAMLMLGLKALYDLAD--PVIVRGMAALDRFV
IETA-FYRVQPC-VSPVWDTALVMRSLIDSGM--SDDPHLVKAGEWLIEKQIL--DYGDWAVNKQGKPGAWAFEFDNRFYPDVDDTAVVVMALCQVQLPT
E--NLEDLKWEAIARSVAWISTMQCKAGGWAAFDLDNDQDW---LNPYADLKAM-IDPNTADVTARVLEMIGYVRRSLDKVDKSITSWQILRALNYLQAE
QEAEGCWFGRWGVNYIYGTSGVLAALAGIAADSH-TPLIKNGATWLISCQN-DGGWGETCRSYNDLKGQG--VSTASQTGWAVIGLLAAGE--TAWDQID
KGIEYLVSTQRSLGDWYEAEFTGGFPCHFYLKYHLYQQHFSLTALGRYLKAKTNY--
>tr|L8LVW7|L8LVW7_9CHRO Squalene-hopene cyclase OS=Gloeocapsa sp. PCC 73106 GN=GLO73106DRAFT_00040020 PE=4 SV=1
---------------------------------------------------------------------------------------------LLDCLSS
SQAYLLSLQKPEGYWWAELESNVTMTAEAILLHKIWGNDKTRS----LSKAELYLRSQQREHGGWELYFGDGGDLSTSVEAYMALRLLNVPPEDP---AL
LQAKQFILSRGGITKTRIFTKLHLALIGCYDWRGIPSIPPAIMLLPSGYTLSIYEMSSWARSSTVPLLIVFDRRPVFRV-DPI---NDELYSEGVNAKYE
----------L----DIF--VTLDGIF-KV----AQDW-LMPWREEGLKAAEKWILEREASGDWGGIIPAMLMLALKCLYDVAD--PVVERGFQALDRFA
IETE-TYRMQAC-VSPVWDTALAVRSLIDAGI--SNHPALVKAGEWLLSKQIL--DYGDWAVNTEGKPGGWAFEFENRFYPDVDDTAVVIMALAAIQTNN
E--PL---KQQAIKRGVDWISTMQCKPGGWAAFDVDNDQDW---LNPYGDLKAM-IDPNTADVTARVLEMLGKLEQTDLDLWASLTSERIEKAIAYLIRE
QEADGSWFGRWGVNYIYGTSGVLSALAFVAGKNY-KSSIQRGAQWLIQHQN-DGGWGETCESYKDLKGKG--QSTASQTAWALIGLLAVGE--TAWESID
KGIEFLRNTQKTDGSWKEDYFTGGFPGHFYIRYHLYYQHFPLTALGRYQVALKQR--
>tr|A0A081GKY9|A0A081GKY9_9CHRO Squalene cyclase OS=Cyanobium sp. CACIAM 14 GN=ER33_09275 PE=4 SV=1
---------------------------------------------------------------------------------------------VQAAIQS
SRNHLLSIQHPEGYWWSELESNVTMTAEFILLHKIWKTDAGRP----WHKAESYLRSQQRDHGGWELFFGDGGDLSTSVEAYMALRLLGAQQTDP---AL
VAASEFILEKGGIEKCRIFTKFHLALIGCYPWAGVPSIPPWVMLFPNWFPFTIYELSSWARGSTVPLLIVFDQKPVFPV-DPI---RDELYRDPRATHPS
----------L----DVF--VLLDGAF-KL----MERL-LVPFRRWGLRAAERWVLEREASGDWGGIIPAMLLLALRTLYAACD--PIVARGMEAVDRFT
IESA-QIRVQPC-VSPVWDTALTVRALGASGL--ADHPALARAGEWLLNKQIL--DYGDWAINRRGKPGAWAFEFENRFYPDVDDTAVVVMALATVSLAD
E--PR---KRQAMQRGVAWILSMQCRPGGWAAFDLDNDQAW---LNPYADLKAM-IDPNTADVTARVLEMLGRLG-------HRGNADQIERGLAYLLRE
QEPEGCWFGRWGVNYIYGTSGALAALAWISPERH-IRAMERGVRWLLQCQN-DGGWGESCRSYSDLKGVG--KSTSSQTAWAMIGLSAFAA--ATAPALE
RGAGYLVKAQRPDGTWEEAEFTGGFPCHFYLKYHLYQQHFPLTALSGYARLGVSP--
>tr|K9V4Q0|K9V4Q0_9CYAN Squalene-hopene cyclase OS=Calothrix sp. PCC 6303 GN=Cal6303_3753 PE=4 SV=1
---------------------------------------------------------------------------------------------LSQSIAS
SQNYLLSRQYGDGFWWSKLESNVTITAEAVLLHKIWGTDTSRP----LNKIEAYLRSQQREHGGWELFYGDGGEISTSVEAYMALKLLGVTADDA---AM
IRARDFILQHGGISKTRIFTKFHLALIGCYSWRGVPSLPPWVMLLPDNPWFSIYELSSWARSSTVPLLIVFDKKPVYVT-NPI---TDELYTEGIEVKYE
----------I----DVF--LGLDQVF-KF----AESW-LVPLRKAGIEAAEKWILEREATGDWAGIIPPMLLLALRSLYDVND--PIVQRGLTAIDNFA
IETD-SYCVQPC-VSPVWDTAWVMRSLVASGV--PDHPAIVKAGEWLLQKQIL--DYGDWAVNRHGKPGAWAFEFENRFYPDVDDTAVVVMALDVAKLPN
E--NL---KTAAIERALDWVASMQCEAGGWAAFDLNNNQDW---LNPYADLKAM-IDPNTADVTARVIEMLGAC-H------LSIPHPNLERALEYLIKE
QESEGCWFGRWGVNYIYGTSGVIAALALVNPHKH-QANIQRGATWLIQCQN-DGGWGETCRSYNDLKGKG--NSTASQTAWAILGLIAADE--IMKVAIE
RGINYLLDTQQEDGSWYESEFTGGFPCHFYLKYHMYQQYFPLLALGRYTADLREI--
>tr|L8LW46|L8LW46_9CYAN Squalene-hopene cyclase OS=Xenococcus sp. PCC 7305 GN=Xen7305DRAFT_00007590 PE=4 SV=1
---------------------------------------------------------------------------------------------VQKAIAL
SQEYLLSIQYPDGYWWAELESNASITSEMVLLHKIWGTDATRP----LEKSASYLRSQQRDHGGWELFYGDGGELSVSVEAYMALRLLGVPKEDP---AL
VKAKKFILQRGGISKSRIFTKLHLALIGCYGWEGIPSLPAWVMLLPKESPFTIYEMSSWARGSTVPLLIVFDKKPVFDI-NPI---SDELYTESIDVRYE
----------L----DIF--IGLDHLF-KL----GETL-LVPFRKEGLKAAEKWILEREATGDWGGIIPAMLLLGLRCLYDVDD--PIIQRGLVAVDNFA
IETE-SYRIQPC-ISPVWDTAWCLRAFAESGF--PDHPALVKAGEWLLDKQIL--DYGDWIVNSQATPGGWAFEFDNRFYPDLDDSAVVVMGLDLVKLPD
E--ML---KQKAIARCLDWMLSMQCQAGGWAAFDINNDQDW---LNPYSDLKAT-IDPNTADVTARVLEMIGLC-Q------LPIPEEQAEKAIAFLLNE
QEADGSWFGRWGVNYIYGTSIALCALEALDPQKY-QENINRGAAWLTTCQN-DGGWGETCRSYNDLKGQG--VSTASQTAWALIGLLAAPD--NGENAIA
KGIDYLIKTQRDDGTWNEDEFTGGFPCHFYLKYHLYQQYFPLMALGRYAQSH-----
>tr|I4G2V7|I4G2V7_MICAE Squalene--hopene cyclase OS=Microcystis aeruginosa PCC 9443 GN=shc PE=4 SV=1
---------------------------------------------------------------------------------------------TAKAIEL
SQNYLLSTQYSEGYWWAELESNVTITSEAILLHKIWKTDKNRP----LDKAATYLRRQQCPNGAWELFYGDGGDLSTTVEAYMGLRLLGIPANDP---TL
EKAREFILAQGGISKTRIFTKMHLALIGCYDWLGVPSIPAWIMLLPENFPFTIYEMSSWARGSTVPLLIVFDKKPVYKM-G-F---NDELYTEGLNVKYE
----------L----DVF--LWLDGLF-KW----AEKT-LVPFRQESLKAAEKWVIEREDTGDWGGIIPAMLLLALKALYDVDD--PIVARGLKAVDNFA
IQTD-TYCVQPC-VSPVWDTAWVIRSLIESGL--NAHPAIIKAGQWLIDQQIL--DYGDWAINKIGTPGGWAFEFDNRWYPDLDDSAVVVMALELIKMPD
E--NI---KKGVMKRAVNWMATMQCKAGGWGAFDIDNDQNW---LNPYADLKAM-IDPNTADVTARVLEMLGTC-D------VKMEENRVKKALDYLEKE
QEADGSWFGRWGVNYIYGTSGALSALAFLEPNKY-RQQLQKGANWLSGCQN-DGGWGETCFSYNNFKGQG--NSTASQTAWALIGLLAVGK--TQREVIE
KGVNYLLVTQKENGTWDEDYFTGGFPCHFYLKYHFYQQYFPLLALGRYRALI-----
>tr|D4TT96|D4TT96_9NOST Terpene synthase OS=Raphidiopsis brookii D9 GN=CRD_01780 PE=4 SV=1
---------------------------------------------------------------------------------------------ITQAIAA
SQEYLLSIQRPEGYWWGELESNVTITVEVLLLHKIWGTCQNRA----LYKIENYLRCQQREHGGWELYYGDGGDLSTSVEAYMGLRLLGVPVTDA---AL
VKAKSWILKKGGISKTRIFTKLHLALIGCYNWRGLPSLPPWVMLLPDYFPFNIYELSSWARSSTVPLLIVFNRKPVFDI-DSI---SDELYAEGIDAQWS
----------L----DIF--TLLDDGF-KL----AENL-LVPLRDQGIKAAEKWILERESTGDWGGIIPAMLLLALKCLYKPDD--PIIYRGLKAVDNFV
IETD-SYCVQPC-VSPVWDTAWAIRSLIDSGM--VDDPVIVKAGEWLIDKQII--DYGDWGVNKQGQPGAWAFEFDNRFYPDVDDSAVVVMALHQAKLPN
E--NL---KKQAIKRAVNWIISMQCKSGGWAAFDIDNDQEW---LNPYGDLKAM-IDPNTADVTARVIEMLGVC-K------LSIPSQKLDQAMNYLLGE
QETEGCWFGRWGVNYIYGTSGVLSALALINPQKY-LSNLEKGASWLKQVQN-DGGWGETCLSYGDLKGKG--DSTPSQTAWGLMGLIAAGE--GDFTSME
KAVNYLLTTQRLDGTWHESYFTGGFPGHFYLKYHLYQQYFPLLALGRYRRIVKST--
>tr|Q118B5|Q118B5_TRIEI Squalene-hopene cyclase OS=Trichodesmium erythraeum (strain IMS101) GN=Tery_0727 PE=4 SV=1
---------------------------------------------------------------------------------------------VKQSILA
SQKHLLSLQETEGYWWGQLESNVTITAEIILLHKIWQTDKKIP----LNKAKNYLISQQREHGGWELFYGDGGDLSTSIEAYMALRLLGVSRTDP---IM
IEAQNFIIKKGGISCSRIFTKLHLALIGCYSWQGIPSIPSSIMLLPEDFPFTIYEMSSWARSSTVPLLIVFDKKPIFSV-NPI---NDELYAEGINASFE
----------L----DLF--LGLDKAF-KF----AENL-LMPLQQEGLKAAEKWILEREVTGDWGGIIPAMLMLALKCLYDVAD--PVVVRGLEAIDRFA
IENE-SYRVQAC-VSPVWDTAWVIRSLVDSGI--SSHPAMVKAGQWLLQQQIL--DYGDWVFNKFGKPGGWAFEFMNRFYPDIDDTAVVVMALDVVELPD
E--DL---KGKAIARGMEWIASMQCEAGGWAAFDVDNNQDW---LNPYGDLKAM-IDPNTADVTGRVLEMVGCC-G------LAMDSWRVKRGIDFLVRE
QEEEGCWFGRWGVNYIYGTSGVILALAVMARESH-RGYIERGASWLVGCQN-DGGWGESCWSYNDLKGKG--KSTASQTAWALIGLLAAGE--TARDAID
GGVGFLVSTQNDDGSWLEDEFTGGFPGHFYIKYHFYSQYFPLMALGRYESLLSG---
>tr|U5QM17|U5QM17_9CYAN Squalene-hopene cyclase OS=Gloeobacter kilaueensis JS1 GN=shc PE=4 SV=1
---------------------------------------------------------------------------------------------LERAIEA
SQGHLLARQSAAGYWWAELESNVTMTAEVVLLHKIWGTDGERA----LTKAAAYLLGEQRAHGGWELFYGDGGDLSTSIEAYMGLKLLGLSAAHP---AL
VRAREFIVSRGGISRSRIFTKIHLALIGCYDWRGIPSLPPWAMLLPAGLPVSIYELSSWARGSTVPLLVVFDRKPVFAT-DPI---TDELYAEGRAARFE
----------L----NLF--VDLDRVF-KL----SESL-AVPWREEGVRAAERWVIEREASGDWGGIIPAMLLLALRCLYDACD--PVVRRGMVAVDRFV
IETE-TYRVQPC-VSPVWDTALTMRALVDAGC--ADHPALVRAGEWILTQQIL--DYGDWSINTAGPPGGWAFEFVNRYYPDVDDTAVVVMALEAVRLPD
E--VA---KRQAMVRAERWVASMQCREGGWAAFDIDNDAHW---LNPYADLKAM-IDPNTADVTARVLEMYGRT-A------LTIDPQSRRRALDYLRRV
QEPEGCWFGRWGVNYIYGTSGVIAALVPFAPEE--RAAIERAAAWLVQCQN-DGGWGETCRSYDDLMGQG--PSTASQTAWALIGLIEAAH--TARSAID
RGIAYLLSTQKSDGSWDEAHFTGGFPGHFYLKYHLYQQHFPLTALGRYRRSFG----
>tr|K9Z5C4|K9Z5C4_CYAAP Squalene-hopene cyclase OS=Cyanobacterium aponinum (strain PCC 10605) GN=Cyan10605_1649 PE=4 SV=1
---------------------------------------------------------------------------------------------VKSGIKQ
AQDYLFSLQEKDGHWCAYLESNVTLTAEAVLLYKIWGIDSHKP----LHKIEHYLRSQQREHGGWELYYGDGGDLSTSVEAYMALRLLGVAQEDE---AL
TKAKRFILSKGGISKSRIFTKFHLAIIGCYDWRGVPSIPPWIMLLPQNPIFTIYEMSSWARSSTVPLLIVFDQKPVFKI-EPI---NDELYSEGKEVKYE
----------L----DIF--VQLDNLF-KF----AEDI-FVPFKEESIRAAQKWIIEREATGDWGGIIPAMLLFAFKTLYHVND--PMVARGLEAVENFA
LETH-DYLVQAC-VSPVWDTAWCLRALVESGV--ANHPALIKGGEWLLDKQIL--DYGDWVVNPHGKPGGWAFEYENRFYPDMDDSSVVIMTLHQLELPR
E--DL---KKEAILRCLRWIETMQCHNYGWAAFDINNDANW---LNPYADLKAM-IDPATADITARVLEMVGSC-D------LPMSSSKVQKAIAFLLHQ
QENDGSWFGRWGVNYIYGTSGALSALAVIAPQTS-QEAMKKGINWLINCQN-DGGWGETCDSYKNLKGKG--NSTASQTAWALIGLLDAGK--LEQDSIN
KGINYLLSSQTETGTWEEKEFTGGFPQHFYINYHLYRHYFPLIALGRFENFLV----
>tr|A0A073CK04|A0A073CK04_PLAAG Shc OS=Planktothrix agardhii NIVA-CYA 126/8 GN=shc PE=4 SV=1
---------------------------------------------------------------------------------------------LKDAIAT
SQNFLFSQQYPEGYWWAELESNVTIISEIILLHKIWGTDKTRP----LYKAETYLRSQQRDHGGWELFYGDGGELSTTVEAYMALKILGVSETDS---AL
IKAKQFILERGGITKTRIFTKLHLALIGCYEWRGIPSIPPWIMLLPEGSPFTIYEMSSWARSSTVPLLIVFDKKPVFRF-NSL---NDELYVERREAIFK
----------L----DIF--LDLDQIF-KF----AELF-IVPLREQGLKAAEKWILEREITGDWAGIIPAMLLLALKCLYPVSD--PIVQRGLEAIDNFA
IETE-SYRMQAC-VSPVWDTAWVVRALIESGI--DNNADIVKSSKWLIRQQIL--DYGDWNINKQGKPGGWAFEFANKFYPDLDDSAVVVMALNQAKITD
E--PL---KTATIIRGIDWMISMQCKAGGWAAFDIDNDQDW---INPYGDLKAM-IDPNTADVTARVIEMLGELDPNSSQLKIQSLKPSIERAISYLKQE
QETDGSWFGRWGVNYIYGTSGVLSALAVINPIYK-NPLMERGTNWLVSCQN-DGGWGETCHSYNDFKGKG--VSTASQTAWALIGLMAT----GEMEVIQ
RGINYLISIQLSDGRWDESEFTGGFPGHFYIKYHYYQHYFPLLALGRYQKLQQL---
>tr|Q7NE23|Q7NE23_GLOVI Squalene-hopene cyclase OS=Gloeobacter violaceus (strain PCC 7421) GN=shc PE=4 SV=1
---------------------------------------------------------------------------------------------LDSAIEA
SQAYLLARQYSPGYWWAELESNVSMTAEVVLLHKIWRTDTGRP----LAKATAHLLAEQRAHGGWELFYGDGGDLNTSIEAYMALKLLGLTADHP---AL
ARARAFILAKGGISRARIFTKIHLALIGCYDWRGVPSIPPWVMLLPEAFPVNIYEMSSWARGSTVPLLIVFDRKPVFAV-EPI---TDELFVEGRAARFD
----------L----NLF--VDLDWGF-KL----AESL-AVPLREEGLKAAERWVLEREATGDWGGIIPAMLLLALRCLYDPHD--PVVERGMAAVDRFA
IETE-TYRLQPC-VSPVWDTALTMRALVDSGL--PDHPALAAAGTWLLKKQIL--DYGDWAVNRTGPPGGWAFEFDNRFYPDVDDTAVVVMALDAVRLAD
E--TA---KGQAIARAVCWVASMQCRGGGWAAFDIDNDAHW---LNPYADLKAM-IDPNTADVTARVLEMYGRC-R------LIPAAAGAQRALDYLRRT
QEPEGCWFGRWGVNYLYGTSGVLSALAAFAPAE--RTAIERAAAWLRGCQN-DGGWGETCGSYVDLMGQG--PSTASQTAWALLGLIDASR--ADSSALE
RGLAYLVETQKADGSWDEPYFTGGFPGHFYLKYHLYQQHFPLSALGRYRRLLS----
>tr|A0A077JG41|A0A077JG41_9CYAN Squalene-hopene cyclase OS=cyanobacterium endosymbiont of Epithemia turgida isolate EtSB Lake Yunoko GN=shc PE=4 SV=1
---------------------------------------------------------------------------------------------LSQAILS
SQDYLLSQQYPDGYWCGELESNVTLTAETVLLHKIWGTDTILP----LHKVETYLRRQQNEQGGWELFYSDGGEISTSVEAYMALRLLGVSQEDP---AL
IRAKDFILSKGGISKTRIFTKFHLALIGCYDWRGIPSIPPWIILFPNNFFFNIYEMSSWARESTVPLLIVFNEKPVFQI-DPF---TDELYAEGITVKYI
----------L----DIF--LILDKIF-KW----SRKN-LVPFYKKSIQASEQWILNHQESGDWGGIMPPMILIAFRVLYDVAD--PCVQRGFEAIDRFS
IEDE-TYRVQAC-VSPVWDTGWALRSLVESGL--KDHQGLVKGGEWLLNQQVL--DYGDWAINHKGKPGGWSFEFTNRFYPDLDDSGVIVMALHGVKLPD
E--NR---KQAAINRCVEWMATMQCKPGGWAAFDVNNDKNW---INPYGDLKAM-IDPNTADITARVLEMLGSC-G------LEIDGDRVQKALTYLDKE
QEADGSWFGRWGVNYIYGTSGVLSALAVIAADTH-KPQMEKAINWLVSCQN-DGGWGETCWSYDDLKGIG--VSTASQTAWALIGLLDTGK--LATDAIK
RGINYLLASQTIEGTWEEAEFTGGFPCHFYIRYHLYCHYFPLMALGRYYKLSSQM--
>tr|A0A0D6AAS4|A0A0D6AAS4_9CHRO Squalene--hopene cyclase OS=Geminocystis sp. NIES-3708 GN=GM3708_231 PE=4 SV=1
---------------------------------------------------------------------------------------------THTAIKQ
AQDYLFSLQKNDGHWCAYLESNVTITAEAVLLYKILGVDNQKP----LHKIEHYLRSQQRSHGGWELYYGDGGELSTSVEAYMALRLLGVSIDDS---AL
VKAKKFILSKGGISKSRIFTKFHLALIGCYDWRGVPSIPPWIMLLPNNPFFTIYEMSSWARSSTVPLLILFDKKPIFPI-QPI---KNELYSEGIHVKYE
----------M----DIF--GHLDNLF-KL----AEDW-IVPFKEQSIQAAEKWIIEREVTGDWGGIFPPITLLAFKILYHVND--PIVVRGLEAAENFA
IETH-DYLVQSC-ISPVWDTTWSLRALVESGI--SNHPQLVKGGEWLLNKQIL--DYGDWIVNPQGKPGGWAFEYENRFYPDMDDSAVTVMTLHQLELPH
E--NE---KKEAILRCLRWIETMQCQNKGWAAFDINNDANW---LNPYADLKAM-IDPATADITARVLEMVGSC-D------LSMKGDKIQNAISFLIHQ
QEKDGSWFGRWGVNYIYGTSGVLSALAVIAPQIH-QLEIEKGINWLISCQN-DGGWGETCESYKNLKGKG--DSTPSQTAWALIGLLDGGN--LAENSIN
QGIKYLLSTQNDNGTWEEKHFTGGFPGNFYINYHLYRHYFPLIALGKYRKFCYQ---
>tr|B4WIK8|B4WIK8_9SYNE Squalene-hopene cyclase OS=Synechococcus sp. PCC 7335 GN=S7335_2248 PE=4 SV=1
---------------------------------------------------------------------------------------------LTQSVVA
AQQHLLSIQNPEGYWWANLESNASITAEVVLLHKIWGTLDSQP----LAKLENYLRAQQKTHGGWELYWNDGGELSTSVEAYMGLRLLGVPASDP---AL
VKAKQFILHRGGVSKTRIFTKFHLALIGCYRWQGLPSLPAWVMQLESPFPFSIYELSSWARGSTVPLLIVFDKKPVYPL-QPP---TDELFTESAEVRWE
----------L----DAF--LWLDKAF-KL----AESV-LVPFREESIRKAEKWVLEREPSGDWGGIIPAMLMLALRALYSVSD--PVVRRGFQAIDNFM
VESE-ECWAQPC-ISPVWDTGLAVRSLTDSGL--SNHPALVKAGEWLLDKQIL--SYGDWSVNPQGQPGGWAFEFENSFYPDVDDTAVVAMALQDITLPN
E--PL---KRRAIARAVRWIATMQCKTGGWAAFDINNDQDW---LNPYGDLRAM-IDPSTADITGRVLEMHGRFAADLDSYAADLSPYRLSRGLNYLIKE
QELDGSWFGRWGVNYIYGTGQALSALALIAPERC-RIQIERGIAWFVSVQN-DGGWGETCESYKDLKGKG--ISTASQTAWALLGLLDVSF--LAKIAVD
RGIQYLVSTQ-SEGTWQEESFTGGFPQHFYLRYRLYCHYFPLMALGRYQRVINSS--
>tr|A0A068MR22|A0A068MR22_SYNY4 Squalene--hopene cyclase OS=Synechocystis sp. (strain PCC 6714) GN=shc PE=4 SV=1
---------------------------------------------------------------------------------------------VRQAIAA
SRDFLLSEQYADGYWWSELESNVTITAEVVILHKIWGTASQRP----LEKAKNYLLRQQREHGGWELYYSDGGELSTSVEAYTALRILGVPATDP---AL
IKAKNFIVGRGGISKSRIFTKMHLALIGCYDWRGTPSIPPWVMLLPNNFFFNIYEMSSWARSSTVPLMIVCDQKPVYNI-AQL---RDELYTEGVEVQYK
----------L----DIF--IGLDSLF-KL----QEQA-VVPFREQGLALAEKWILEREVSGDWGGIIPAMLLLALKVLYDVND--PYVQRGLAAIDNFA
VETE-TYSIQAC-VSPVWDTAWVVRALAEADL--GDHPALVKAGQWLLDKQIL--TYGDWQINPQGKPGAWAFEFDNNFYPDIDDTCVVMMALQGITLPD
E--ER---KQGAIDKALQWVATMQCKTGGWAAFDIDNDQDW---LNPYGDLKAM-IDPSTADITARVIEMLGAC-G------LTMDRQRVARGLAYLLQE
QEQDGSWFGRWGVNYLYGTSGALSALAIYDAQRF-IPQIKMAIAWVLSCQN-DGGWGETCESYKNLKGKG--SSTASQTAWALIGLLDAAK--DLMTAIE
RGVAFLIAGQTTKGTWEEAEFTGGFPCHFYIRYHYYRQYFPLIALARYSHLRAF---
>tr|A0A0D6AR54|A0A0D6AR54_9CHRO Squalene--hopene cyclase OS=Geminocystis sp. NIES-3709 GN=GM3709_1659 PE=4 SV=1
---------------------------------------------------------------------------------------------ANTAIRK
AQDYLFSLQQEDGHWCAYLESNVTITAEAVLLYKIWGIDNQKP----LHKIEHYLRSKQCSHGGWELYYGDGGDLSTSVEAYMALRLLGVSIDDT---AL
ERAKKFILSKGGISKSRIFTKFHLALIGCYDWRGVPSIPPWIMLLPNNPLFTIYEMSSWARSSTVPLLIVFDRKPIFAV-EPI---KDELYSEGIKVKYE
----------M----DIL--GQLDNLF-KI----AEEW-IVPFKEQSIQAAEKWIIEREVTGDWGGIIPAMLLLALKTLYHVND--PMVARGLNAVENFA
IETH-DYLVQAC-VSPVWDTTWCLRALVESGV--INHPNLVKGGEWLLDKQIF--DYGDWVVNPQGKPGGWAFEYENRFYPDMDDSAVVVMTLNQLELPQ
E--NL---KREAILRCLRWIETMQCHNHGWAAFDINNDANW---LNPYADLKAM-IDPATADITARVLEMVGSC-D------LPMKASKIQNAIGYLIRQ
QEEDGSWFGRWGVNYIYGTSGVLSALAVIAPRIE-KNVIEKGINWLVSCQN-DGGWGETCESYKHLKGKG--DSTPSQTAWALIGLLDGGN--IAEDNIK
KGIRYLLTNQNDQGTWEEKQFTGGFPGHFYINYHLYRHYFPLIALGKYEKFLVKN--
>tr|A0A086CI45|A0A086CI45_ATETH Squalene-hopene cyclase OS=Candidatus Atelocyanobacterium thalassa isolate SIO64986 GN=ucyna2_00238 PE=4 SV=1
---------------------------------------------------------------------------------------------LDNAIDI
SQKYILSLQNSEGYWLGELESNVTLTAETVLIYKIWGIFENLS----KSKIEAYLCNKQNKYGGWELFYGDGGEISTSIEAYMALRLLGLSKDNP---VL
VSARKFILSKGGISKARIFTKFHLALIGCYSWEGLPSIPPSIMVLSNNFPFTIYEMASWARESTVPLIIVFDKKPIFPI-NPF---NNELYVEDIEVQYK
----------L----DIF--LWLDKIF-QL----LGKF-LIPFRKRGLKEAEKWILDHQESGDWGGIMPPMLLIAFKTLYDIED--PSVKRGFEAIQRFA
IEKD-DYYVQAC-VSPVWDTAWMIRALTESGL--SDHRSLQIAGDWLLSKQCL--DYGDWAINKIGKPGGWAFEFTNRFYPDIDDSAAVIMALEGITLVN
E--QQ---KKAAINRCLQWIKTMQCKTGGWAAFDIDNNQAW---LNPYGDLKAM-IDPNSADITARVLEMLGSC-N------LEMSDERTAKALNYLYDE
QEEDGSWFGRWGVNYIYGTSGVLSALAVLHPDKN-YSQLKRGVSWLLSCQN-DGGWGETCLSYDNLKGEG--ISTASQTAWSLIGLLDAGK--LAINHID
RGINYLVNTQTSTGEWKEKEFTGGFPSHFYIRYHLYSNYFPLIALGRYQKLRHLF--
>tr|D3EQ48|D3EQ48_ATETH Squalene-hopene cyclase OS=Atelocyanobacterium thalassa (isolate ALOHA) GN=UCYN_09140 PE=4 SV=1
---------------------------------------------------------------------------------------------LDNAINI
SQDYILSLQHPEGYWVGELESNVTLTAETVLLYKIWGISESLP----NCKIKAYLCNQQNKYGGWELFYGDGGEISTSIEAYMALRLLGMSKEDS---IL
VNAKKFILSKGGISKARIFTKFHLALIGCYSWKGLPSIPPWIMALNNNLPFTIYEMASWARESTVPLIIVFDKQPTFLI-DSF---NNELYVEEIGIQYG
----------L----DIF--LWLDKIF-QV----LGKF-LVPFRERGLREAEKWMLNHQESGDWGGIMPPMLLIAFRTLYDLED--PSVRRGLEAIQRFS
IEKD-DYYVQAC-VSPVWDTAWMIRALTESGL--SNHLSLQLAGDWLLSKQCL--DYGDWAVNKLGKPGGWAFEFTNRFYPDIDDSAAVVMALEGINLVN
E--QQ---KEAAISRCLQWIETMQSKTGGWAAFDIDNNQSW---LNPYGDLKAM-IDPNSADITARVLEMLGSC-N------LKISDKRITKALNYLYSE
QEKDGSWFGRWGVNYIYGTSGVLSALAVLNSDEN-HSQLSKGVNWLLSCQN-DGGWGETCFSYDNLKGKG--ISTASQTAWSLIGLLDAGK--LATNHID
RGIEYLLNTQTNSGTWEEEEFTGGFPSHFYIRYRLYCIYFPLIALGRYKQFKHLF--
>tr|G2LJM4|G2LJM4_CHLTF Squalene-hopene cyclase OS=Chloracidobacterium thermophilum (strain B) GN=Cabther_B0033 PE=4 SV=1
---------------------------------------------------------------------------------------------VEAAIRK
AQAYLLSKQYPEGYWWAELEANVTLTAEYVFLHKVLGTDGERTR-Q-FEKIRTYLRRQQREHGGWELYYGDGGELSTSIEAYFALKLLGDSPDLP---HM
ARARQFILARGGITKARVFTKIHLALFGAFPWEGCPTLPPWIMLLPDWFPFTIYELASWARSSTVPLLLVSDRKPVVRV-PGD----DELYAEGRAADL-
----------S----GVF--IGFDWML-KL----MERF-LSPRRAEALARAEQWTLEHDDSGDWGGIIPAMLLLGLHCRYAPTH--PVMQKGIAAVERFC
IETEEFH-TQPC-VSPVWDTGLTILALLDSGL--PDHPALVRAGEWLLSKQIF--RDGDWRFNRTGPAGGWAFEFWNDFFPDVDDTAVVTMALHRLKLPD
----E-AEKQRRLKLAIEWTLSMQSKNGGWGAFDVDNTLEI---LNPYGDLKAM-IDPPTADLTGHILEMLGVTG-------YAAPREKVERAIAFIKSK
QEPEGCWWGRWGVNYIYGTHMVICGLVALGLDPR-EAFIMRGTQWLNSCQN-DGGWGETCASYGDLMGVG--KSTPSQTAWALLGLMAGGE--KS-DCAR
RGIEYLVTHQNDDGSWTEAEFTGGFPNHFYMNYHFYRNYFPLMALGRYRAFART---
>tr|C6E1N3|C6E1N3_GEOSM Squalene-hopene cyclase OS=Geobacter sp. (strain M21) GN=GM21_0885 PE=4 SV=1
---------------------------------------------------------------------------------------------LDVAIEG
SRDFFFQEQLPKGYWWAELESNVTITAEYIMLFHFLGLVDR-E--R-QRKMSNYLLSKQTEEGFWPIYYGGPGDLSTTIEAYFALKLSGYPADHP---AL
AKARAFILEQGGVVKSRVFTKIFLALFGEFEWQGVPSMPVELNLLPDWAYINIYEFSSWARATIVPLSVVMHSRPVRRV-PPA---RQELFVRQPTADY-
----------S----NFF--LGLDRVL-KV----YEKS-LRPFKNMALAKAEEWVLEHEPTGDWGGIQPAMLVLALNVLYQNDH--PAVEQGLRALANFC
IETEQLV-LQSC-VSPVWDTALALKALLDAGV--PDHPSLVKGAQWLLDKEVT--RPGDWRVSPALEPGGWAFEFLNDWYPDVDDSGFVMIALKGIQVKD
----R-KSMDAAIKRGINWCLGMQSKNGGWGAFDKDNTRHV---LNPFADLEAL-IDPPTADLTGRMLELMGTFN-------YPITLPAAQRAIEFLKKN
QEPEGPWWGRWGVNYLYGTWSVLCGLAAIGEDMD-QPYIRKAVNWIKSRQN-DGGWGETCQSYHDLAGVG--ESTPSQTGWALLGLLAAGE--HS-ATVV
RGVQYLISTQNSDGTWDEQQYTGGFPKYFMIKYHIYRNCFPLMALGTYRTLTRTQ--
>tr|A0A0B5B7W3|A0A0B5B7W3_9DELT Squalene cyclase OS=Geobacter pickeringii GN=GPICK_04085 PE=4 SV=1
---------------------------------------------------------------------------------------------LDLAIER
SRDFFFREQLPEGYWWAELESNATITAEYLMLFRFMGLMDK-E--K-ERKMANYLLREQTEEGCWCIYFGGPGDLSTTIEAYFALKLAGYPADHP---AM
QKARAFILERGGILKARVFTKIFLALFGEFSWLGVPSMPIEMMLLPNGFTFNLYEFSSWSRATIIPLSIVMAERPVRKL-PPA---RQELYVRPPRTDY-
----------T----NIF--IGIDHVL-KV----YEAS-IRPGMKRALAKAENWVLEHEPTGDWGGIQPAMLVLALHCLYAKDH--PAVARGLQALANFA
IEGEELV-LQSC-VSPVWDTALGLMAMVDAEV--PDHPALVKAAQWLLDREVR--KPGDWKVAPDLEPGGWAFEFLNDWYPDVDDSGIVMMALKDVKVKD
----Q-KAKEAAIKRGIAWCLGMQSKNGGWGAFDKDNTKHI---LNPFADLEAL-IDPPTADLTGRMLEVMGTFG-------YPKDDQVAVRALQFVKDA
QEPEGPWWGRWGVNYIYGTWSVLCGLDAFGEDMN-QPYIRRAVNWLKSRQN-DGGWGESCASYDDLAGIG--ESTASQTGWALLALLAAGE--ES-PAVA
RGVQYLIDTQKPDGTWDEQQFTGGFPKYFMIKYHIYRNCFPLMALGRYRSQKRQK--
>tr|E8WLT7|E8WLT7_GEOS8 Squalene-hopene cyclase OS=Geobacter sp. (strain M18) GN=GM18_3439 PE=4 SV=1
---------------------------------------------------------------------------------------------LDIAIEG
CRDFFFREQLPKGYWWAELESNVTITAEYIMLFNFLSLVDH-E--R-QRKMSNYLLSKQTEEGFWTIYYGGPGDLSTTVEAYFALKLTGYPADHP---AM
VKARAFILEKGGVIKSRVFTKIFLALFGEFDWLGVPSMPVELNLLPNWAYVNVYEFSSWARATIIPLSIVMLKRPVHKL-PPQ---RQELFVRPPRIDY-
----------T----NFF--IGLDHML-KV----YERS-VRPFKKRAMGKAEEWVLEHEETGDWGGIQPAMLVLALSALYDNGH--PAVAHGLKALENFC
IESDQIV-LQSC-ISPVWDTALALKALVDAGV--PDHPSLVKGAQWLLEREVR--RPGDWRVSPDLEPGGWAFEFLNDWYPDVDDSGFVMIALKGVEVKD
----R-KAMNAAVKRGIDWCLGMQSKNGGWGAFDKDNTRHI---LNPFADLEAL-IDPPTADLTGRMLELMGTFG-------YAKTYPAAQRALKFLKEN
QEPEGPWWGRWGVNYLYGTWSVLCGLAAIGEDLE-QPYIKKAVNWIKSRQN-DGGWGETCESYHDLAGMG--ESTASQTGWALLGLMAAGE--HS-ATVV
RGVQYLISTQSQDGTWDETQYTGGFPKYFMIKYHIYRNCFPLMALGTYRTLTGGT--
>tr|A0A0A8WSC1|A0A0A8WSC1_9DELT Shc protein OS=Geobacter sp. OR-1 GN=shc PE=4 SV=1
---------------------------------------------------------------------------------------------LDQAIER
TRDFFFREQLPQGYWWAELESNATITAEYLMLFHFMGIVDK-A--K-ERKMANYLLRQQTAEGYWAIWFGGPGDLSTTIEAYFALKLAGYDAEHP---AM
LKAREFIISKGGILKARVFTKIFLALFGEFSWLGVPSMPIELMLLPNWAYFNMYELSSWSRATIIPLSIVMTMRPVRKL-PPA---RQELYVRPPRIDY-
----------T----NFF--IGVDHLM-KV----YEGN-IRPLKGKAMAAAEKWVLEHEPTGDWGGIQPAMLVLSLHCLYANDH--PAVEKGLKALDNFC
IEDDSLV-LQSC-ISPVWDTALALKALVDAGI--PDHPALVKAAQWLLDREVR--KEGDWKISPDLKPGGWAFEFLNDWYPDVDDSGFVMLAIKEIAVKN
----E-KAREGAIKRGIEWCLGMQSKNGGWGAFDKDNTKHL---LNPFADLEAL-IDPPTADLTGRMMELMGSFG-------YSGDFPAAARGLEFLKRE
QEKDGSWWGRWGVNYIYGTWSVLSGLAAIGEDLS-QPYIRKAVGWIKSKQN-DGGWGETCESYYDLAGIG--PSTASQTGWALLALMAAGE--NA-PETA
RGIQYLLSTQKSDGTWDEDQYTGGFPKFFMIKYHIYRNCFPLTALGTYRRLVKGE--
>tr|A5GB12|A5GB12_GEOUR Squalene-hopene cyclase OS=Geobacter uraniireducens (strain Rf4) GN=Gura_1020 PE=4 SV=1
---------------------------------------------------------------------------------------------LDIAIEN
SRDFFFREQLPDGYWWAELESNCTITAEYLMLYHFMGIVDQ-E--R-ERKMATYLLSKQTAEGFWTIYFGGPGDLSTTVEAYFALKLAGYPADHP---AM
AKARAFILDNGGIIKCRVFTKIFLALFGEFAWFGVPSMPIELILLPNWAYFNMYELSSWSRATIIPLSIVMTERPVRKL-PPS---RQELYVRPPRIDY-
----------T----NFF--IGVDHIL-KV----YESN-IRPFKKRALATAENWVLDHESTGDWGGIQPAMLVLALHCLYANDH--PAVAKGLEALANFC
IETESLV-LQSC-ISPIWDTALALKALVDSDV--PDHPALVKAAQWLLDKEVR--KPGDWKICPELESGGWAFEFLNDWYPDVDDSGFVMMALKDVAVKD
----R-KSMDGAIKRGINWCLGMQSKNGGWGAFDKDNTKYL---LNPFADLEAL-IDPPTADLTGRMLELMGTFG-------YSKDYPAAVRALEFIKKN
QEPEGSWWGRWGVNYIYGTWSVLGGLAAIGEDLN-QPYIRKAVNWLKSRQN-DGGWGETCESYHDLAGIG--ESTPSQTGWALLSLMSAGE--NS-STVA
RGIQYLIANQKSDGTWDEEQYTGGFPKFFMIKYHIYRNCFPLTALGTYRKLTGGM--
>tr|A0A0C1TKL8|A0A0C1TKL8_9DELT Squalene cyclase OS=Geobacter sp. GSS01 GN=SE37_01355 PE=4 SV=1
---------------------------------------------------------------------------------------------LDIAIER
TQEFFFREQLPAGYWWAELESNVTITAEYIMLFHFMGLVDR-E--K-ERKMANYLLRQQTTAGYWTLWHGGPGDLSTTIEAYFALKLAGYPADHP---AM
SKARAFILEHGGILKARVFTKIFLALFGEFSWLGVPSMPIEMMLLPTGFTFNMYEFSSWSRATIIPLAIVMAERPVRKL-PPA---RQELYVRPPRTDY-
----------T----NIF--IGIDHVL-KV----YEAS-IRPGRKKAMAIAEKWVLEHEPTGDWGGIQPAMLVLALHVLYANDH--PAVARGLQALANFC
IEGDELV-LQSC-VSPVWDTALGLMAMVDSGV--PDHPSLSKAAQWLLDREVR--RPGDWKISPDLEPGGWAFEFMNDWYPDVDDSGIVMMAIKNVKVKD
----Q-RAKEDTITRGIAWCLGMQSKNGGWGAFDKDNTKHI---LNPFADLEAL-IDPPTADLTGRMLELMGTYG-------YPKDHPAGVRALKFIRET
QEPEGPWWGRWGVNYIYGTWSVMSGLAAFGEDMS-QPWIRKAVEWLMSHQN-DGGWGECCESYIDLAGTG--PSTASQTGWALLTLLAAGE--AS-SSVV
RGVQYLLDTQKPDGTWDEDAFTGGFPKFFMIKYHIYRNCFPLMALGRYRALADKG--
>tr|Q39RT6|Q39RT6_GEOMG Squalene cyclase OS=Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210) GN=shc-1 PE=4 SV=1
---------------------------------------------------------------------------------------------LDQAIKR
SQEFFLREQLPAGYWWAELESNVTITAEYVILFHFMGLVNR-D--K-DRKMATYLLSKQTEEGCWCIWHGGPGDLSTTIEAYFALKLAGYPADHP---AM
QKARTFILGKGGILKARVFTKIFLALFGEFSWLGVPSMPIEMMLLPNGFTFNLYEFSSWSRATIIPLSIVMAERPVRKL-PPA---RQELYVRPPRMDY-
----------T----NIF--IGIDHIL-KV----YEAS-IRPGMKKAMAIAEQWVLDHEPTGDWGGIQPAMLVLALHCLYANDH--PAVAKGLQALANFC
IESDEIV-LQSC-ISPVWDTALALMAMVDSEV--PDHPALVKAAQWLLDREVR--KVGDWKIAPNLEPGGWAFEFQNDWYPDVDDSGIVMMAIKDVKVKD
----S-KAKAEAIQRGIAWCIGMQSKNGGWGAFDKDNTKHI---LNPFADLEAL-IDPPTADLTGRMLELMGTFG-------YPKDHPAAVRALQFVKEN
QEPDGPWWGRWGVNYIYGTWSVLCGLKAYGEDMG-QPYVRKAVEWLAAHQN-DGGWGECCESYCDLAGTG--PSTASQTGWALLSMLAAGD--DH-PAVA
RGIRYLIETQQPDGTWDEDQFTGGFPKYFMIKYHIYRNCFPLMAMGRYRALKGHK--
>tr|F2NEV8|F2NEV8_DESAR Squalene-hopene cyclase OS=Desulfobacca acetoxidans (strain ATCC 700848 / DSM 11109 / ASRB2) GN=Desac_0410 PE=4 SV=1
---------------------------------------------------------------------------------------------VEQAAAK
AQKALLELQHPDGYWWAELEANVTITSEYIMLRSFLGLADA-D--R-FSRMANYILSQQLDNGGWSIYHGDGGDLSTTVEAYLALKLAGLQTTMP---EM
QQARQFILSRGGPLQSRVFTRIFLALFGQVSWRGIPTMPVEFVLLPLWTGLSIYELSSWSRATVVPLSVVMAYQPVCPL-PPR---GRELFHPWEDLRDH
----------R----NLF--VFSDKLL-KV----YQGH-YPPLRQWALRRAEEWILTHEETGDWGGIQPAMLILALHCLYSNKH--RAIKLGLEAMEFFT
LAAGRLW-LQSC-ISPIWDTALSVRALTASGL--QTHPAVSKACQWILQQQIF--RRGDWSVNPYLAAGGWAFEFHNNWYPDIDDSAVVLMSLAEGL-QE
----P-QQHRTALDRGVHWCLGMQSQNGGFAAFDTDNTKAW---LNPFADLKAL-IDPPTEDVTSRVLEMMGMFG-------YTADHVAASKAIAFLKSA
QQPDGCWYGRWGVNYIYGTWSVLCGLKGIGEDMS-SPYIRRAVAWLQDHQN-DGGWGETCASYKYLRGQG--PSTASQTAWALLGLIAAGE--GS-PAVA
KGIRYLVQTQTPSGRWEEPYFTGGFPQHFMIRYHLYRDYFPLMALGNYLKSRGHY--
>tr|A1AN91|A1AN91_PELPD Squalene-hopene cyclase OS=Pelobacter propionicus (strain DSM 2379) GN=Ppro_1189 PE=4 SV=1
---------------------------------------------------------------------------------------------LDKGIER
TRDFFLREQLPDGYWWAELESNVTISAEYVMLFHFLGMVDR-E--R-ERKLANYILAKQTSEGFWSLWHNGPGDLSTTIEAYFALKLAGYSADHP---AM
AKARAFVLANGGIIKARVFTKIFLALFGEFAWFGVPSMPIELMLLPDWAYFNMYEFSSWSRATIIPLSVVMSERPVRKL-PPA---QQELFVRPPRTDY-
----------T----NFF--IGADHLI-KV----YESS-IRPFKKRAVALAENWILEHEQSGDWGGIQPAMLILALHCLYANDH--PAVAKGLDALANFC
IEDDCIV-LQSC-VSPVWDTALALVALQEADV--PDHPALVKAAQWLLNLEVR--RKGDWQVCPELEPGGWAFEFLNDWYPDVDDSGFVMLSIKNIKVRD
----R-KHREEAIKRGIAWCLGMQSENGGWGAFDRNNTKYL---LNPFADLEAL-IDPPTADLTGRMLELMGNFD-------YPKSHPAAERALAFLKKE
QESEGPWWGRWGVNYLYGTWSVLCGLEAIGEDMN-QPYIRKAVNWIKSRQN-DGGWGEVCESYFDLMGSG--PSTASQTGWALLALMAAGE--NS-RAAA
QGVKYLLETQNEDGTWDEDAFTGGFPKFFMIKYHIYRNCFPLTALGRYRRLTAAK--
>tr|D8PBL8|D8PBL8_9BACT Shc protein OS=Candidatus Nitrospira defluvii GN=shc PE=4 SV=1
---------------------------------------------------------------------------------------------LEEALRK
SQAWFLARDASEGYWVAELEADTTLTSEYLMLRRFLDCIDP-E--R-ERKAVRYLKSAQLPDGGWPIYHGGPAEISASVKAYFALKLSGVSADEP---FM
VNARTCILDKGGVVAANVFTKIALALFGQYDWRGVPSMPPEIMLLPKRFYFSIYAISYWSRAVLIPLLIIFAKRPMCHV-PSQ---GDELYTQPPAIDYG
----------T----NFF--INLDALL-KI----YDRS-VEWVRQKALKCAENWMLDHKGSGGLGAIYPAMAVMALHCLYKNDD--PLMVKAMREIEELE
IHDTAMH-LQPC-HSPIWDTALLINALIEAGM--PDHPALQKASTWLLFKQTK--TVGDWIISPGAEPGGWYFQFENELFPDVDDSAVVLMALAKVHLSD
----E-AQQRLAIRRGCRWVTAMQGSDGGWGAYDVDNNRIV---FNPFADHRAL-LDPSTADLAGRCLEMLATLG-------YDWTHPAVASALTFVKND
QEQDGSWYGRWGVNYIYGTWSVLSGLRAIGEDLS-SPYIRRAVSWVESKQN-DGGWGESCLSYGDQSGRG--DSTPSQTAWALLALMAGGV--DS-FSLA
RGIHYLIRNQRKDGSWEEVRHTGGFPRVFYLRYHWYCQYFPLWALAMYRNLKTRG--
>tr|A0LLW2|A0LLW2_SYNFM Squalene-hopene cyclase OS=Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) GN=Sfum_2736 PE=4 SV=1
---------------------------------------------------------------------------------------------IEKAIDN
ACGQLFKTQYEDGYWWSELESNVTITSEYIMLLYLLEVSRP-E--Q-QKSMVKYLLNQQRPDGSWGLYYGDGGNLSTTIEAYFALKLAGEHCESE---PM
RRAREFILSKGGIESARVFTKIWLALFSQYDWDKVPSMPVELVLLPSSLYFNIYEFSSWARGTVVPLSIVMSIRPRCPL-PAC---SKELYVPGSKKNF-
----------A----KLF--FLFDRIA-KA----FERR-VPSLRNKAVQAAETWVLDHEDSGDWGGIQPPMVVLALYYLYPLDH--EVIVKGIKALDAFC
MEDEGTR-MQSC-VSPVWDTALTVLSMLDAGV--AEHPGLEKAGRWLLENQVL--TGGDWQINDS-LPGGWAFEFYNTRYPDVDDSAVVLSTLNRFNAER
----V-EGLEFAKCRGMEWCLSMQSSNGGWAAFDKDNTLEI---LNPFADQEAM-VDYPTADVTGRVLEAMGYLG-------YDGSHPRARKAIQFLKKR
QERDGCWWGRWGVNYIYGTWSVLKGLISIGEDPR-AAYIRAAVRWVKDHQN-DGGWGETCESYENLRGQG--PSTPSQTAWALMSLIACGE--KS-QEAS
RGIQYLLRTQKRDGTWEELHFTGGFPKHFYIRYHNYRNCFPLMALGQYLRALER---
>tr|D5MHN5|D5MHN5_9BACT Shc protein OS=Candidatus Methylomirabilis oxyfera GN=shc PE=4 SV=1
---------------------------------------------------------------------------------------------LDEAIEQ
ARSRLLA-QDPAGYWAAELEADSTLTSEYIMLRYLLGKVDE-T--K-QRKAATYLRDTQLPDGGWNIYYGGPSHLSTTVKAYFALKLCGHSQAEP---FM
QRAREVILRQGGLFRANVFTKFTLALFGQFDWRGVPAMPIELFLLPQGSLFNMHAISYWSRTVLTPLMIIFAHKPITPV-PAA---DAELRVGDAPHDY-
----------W----NLF--LAADRVL-RW----YEWH-ISYFRRLAMERATAWMLRR-GEGGLGGIYPAMAVIALRCLYEVEH--SLVARAFKQIEALE
VEDETLH-VQPC-FPPSWDTCLAVNALIASGL--PDHPALITACEWLLSKQTR--TVADWKVAPDAEPGGWYFQFENEFYPDVDDSAVVMTALIKTNLPD
----Q-AIKDAALAQALKWVLPMQSSDGGWASYDKDNNKLF---LNPFADHKAL-LDPPTSDLTGRMLEMLGHLG-------WSNAAPAAQRGIAFLKRE
QEATGCWFGRWGVNYIYGTWSVLAGLRAIGERMD-QPYIRRAVDWLISHQN-DGGWGESCHSYEDTAGQG--PSTASQTAWALLGLLHAGV--RH-PAVK
KGIDYLLRTQGADGDWEEREFTGGFPRVFYLRYHLYRLYFPLWALSLYRTLLQKA--
>tr|L0DEH3|L0DEH3_SINAD Squalene-hopene cyclase OS=Singulisphaera acidiphila (strain ATCC BAA-1392 / DSM 18658 / VKM B-2454 / MOB10) GN=Sinac_2971 PE=4
---------------------------------------------------------------------------------------------LSEAVDS
TSRWLIDGQNSDGYWVGELEGDTILESEYVLLMAFIGRGAE-E--I-CVKACRYLRDLQLPGGGWAIYPGGPPDISASVKAYFALKIVGVPVNDP---AM
VRARECILEAGGAQGCNSFTRFYLALLGQIDYSDCPSVPPEMMLVPSRLGFSLAAMSAWTRTIVVPLSIMSAFKPVRRL-APQ---GAELFRTDLP----
---------------NLF--LGLDRVF-KW----ADDH-PRSWRQPGIRAAHRWMLEHENSDGLGAIFPPMIVVALHCLYEADS--AEVQWAHRQLDDLL
IEEDKVR-VQPC-VSPVWDTAIAAIALADAKV--PYHPALLRAGRWLLEKEVR--VAGDWQVRPGVEPSGWHFQFHNERYPDIDDTAMVLLALQRTALAK
----T-PEVKAATARGVNWLLSMQNRDGGWAAFDVDIDNEV---LTPFADHNAM-LDPSCADITARILECLGTLG-------YRDDHPAVARALNYLWKT
QEPQGCWYGRWGVNYIYGTWQVLQGLKALDYPMD-HPALQKAADWLESVQQ-DGGWGESCQSYDDWMGRG--EPTASQTAWAVLGLVSAGR--RG-EAAS
RGTAYLQATQREDGTWDEGPYTGGFPRVFYLKYHLYRIYFPLMAMSRYQAAAGRV--
>tr|K1YHZ0|K1YHZ0_9BACT Uncharacterized protein OS=uncultured bacterium GN=ACD_73C00155G0001 PE=4 SV=1
---------------------------------------------------------------------------------------------VDQSINM
SVDTLFKHQFQDGFWWYSLEANDSINAEYIFLMHYMECIDLD----VQKAISLQIINNQNEDGSWSIFYGGDGDLSTTIECYLALKLSGISLDSE---SL
TRARRFILMHGGLSQIRIFSRIHLAQFGIIPWSACPVMPAQLIKLPSWFPINIYEFSSWARSCIVPLLVIMAKKRMIPL-GY-----NELYAESDCD---
-----------VDWSQFF--ITLDKA-FKK----LEKFGLKYYTTSSLADCEAWIRQH---EKTEDIYPALAAMALKSLYGLND--PTVKKCMDGLKKFQ
MKSNMQIYQQCC-LSPVWDTPWALEALLDAGVST-SDNRLTNSGNWLISKQVLN-TYGDWSQNKKALPGGWSFEFENEYFPDVDDTLQILKVLQRIDLD-
----E-GLKEKALARGLNWLLSMQCKNGGWAAFDINNTLEL---VNPFSDHGAC-LDPPSPDITGRILELLGQFGFAQ--EF-----QPVKKAIRFIEST
QEEDGSWFGRWGVNYIYGTWCVLKGLNKINYN--DSQLIQKAVKWLKSVQKMDGGFGESCDSYKIYLPLD--ESTASQTSWALMGLLAGEK--V-SPEAH
KAAQYLIKSQKNDGTWDEPHFTGGFPGHFYIRYHGYRHYFPLLALAQYRQSL-----
>tr|B2ICC0|B2ICC0_BEII9 Squalene-hopene cyclase OS=Beijerinckia indica subsp. indica (strain ATCC 9039 / DSM 1715 / NCIB 8712) GN=Bind_3156 PE=4 SV=1
---------------------------------------------------------------------------------------------IETAITR
ARKALLGEQRADGHFVFELEADVSIPCEYILFYHFIGRAPA-E---LEAKIGHYLRARQSEHDGWPLFQD-GFNISSSVKAYFALKAIGDTPDMP---HM
QRARTAILAHGGAAAANVFTRSLLALFGLIPWHGIPVMPIEIMHLPEWFPFHIAKISYWGRTVLVPMMVVHALKPKPAN-TCI----DELFVIPPDVRHW
---------PG----AIF--AGIDKVL-QI----AEPY-PRRSRQSAIDKAVAFVTKRNGEDGLGAIYPAMAALMYLSIRSLSD--PHIQLVLKAIDKLV
VK--HEAYVQPC-VSPVWDTALASHALMEAGDG-DILDSLKKGLAWLKPLQVTD-IAGDWAWKPDVKPGGWAFQYGNAYYPDLDDTAVVVMAMDRARDRW
P-EIDEDNFRPSIARAREWIVGLQSENGGFGAFDADNDRDY---LNPFADHGAL-LDPPTADVTARCISMLTQLGEK----P--ENSETLRRAIAYLFAE
QEKDGSWFGRWGLNYIYGTWSVLCSLNAAGIAHD-APEVRRAVAWLRTIQNEDGGWGEDAESYAL-GYQQA-PSTSSQTAWAVLGLMAAGE--D-DPAVA
RGIAYLTRTQGE-GFWTEKRFTAGFPRVFYLRYHGYSKFFPLWAMARYRNLHNGN--
>tr|B8EQD7|B8EQD7_METSB Squalene-hopene cyclase OS=Methylocella silvestris (strain BL2 / DSM 15510 / NCIMB 13906) GN=Msil_3243 PE=4 SV=1
---------------------------------------------------------------------------------------------VEAAISR
AREALLAVQKPDGHFVFELEADVSIPAEYILFRHFLGDAKT-E---IERKIGVYLRRRQTAAGGWPLFAE-GFNVSSSVKAYFALKIIGDDPNAP---HM
AKARNAILAHGGAAQSNVFTRSLLALYGEVPWRAVPAMPVEIMHLPRWFPFHLSKVSYWGRTVIAPLIVVHALKPRAKN-PRI----SELFVAPAEVSRW
---------PG----TIF--GAIDRVL-HK----TEPL-PARSHQTAIDKAVAFVTARNGEDGLGAIYPAMAAMMFFALAPLSD--PRIVQIRKAIDRLL
IKD-GEAYCQPC-VSPVWDTALASHALMESAGQ-RAAAAVFEALDWLKPLQVLD-VKGDWATNPDVRPGGWAFQYANPHYPDLDDTAVVVLAMDRAVKTS
PLGEEETAYVEAISRAREWILGLQSANGGFGAFDADNDRDY---LNPFADHGAL-LDPPTADVTARCVSMLGQLGER----P--ETSPALARAIDYLLSE
QEEEGSWFGRWGMNYIYGTWSVLSAFNAVERPAD-CAATRKAAAWLKRIQNPDGGWGEDGESYAL-GYNPA-PSTASQTAWALLALMAAGE--D-APEVA
LGLDYLVSTQAD-GFWDEARFTAGFPRVFYLRYHGYAKFFPLWAMARYRNLKSGN--
>tr|N0B376|N0B376_9RHIZ Squalene/oxidosqualene cyclase OS=Hyphomicrobium denitrificans 1NES1 GN=HYPDE_24888 PE=4 SV=1
---------------------------------------------------------------------------------------------LEAAISS
ARNSLLALQRPDGHFVFELEADATIPAEYVLMRHYLGEVDT-V---LEEKIARYLRRIQSDDGGWPLFHD-GSNISAAVKAYYALKMIGDSPDAP---HM
KKARAWILAQGGASHSNVFTRNLLALFGSIPWSGVPVMPVEIMLLPRWFPFHIDKISYWARTVLIPLTVLNALKPRARN-PKI----AELFATPPEVRNW
---------PK----QVF--GGIDRVL-RL----VEPA-PKSLRKKSIDKAVAFVTERNGEDGLGAIFPAMVLLVYDALYPQDH--PDYVTARGSIEKLL
VKD-DEAYCQPC-LSPVWDTALAAHALMESGGA-Q--QSVDRALAWLKPLQVLD-TVGDWAARPGVRPGGWAFQYANPYYPDVDDTAVVVMAMDRAAGRD
A--SKREQYRESMARAREWIAGVQSKNGGWGAFDADNTYEY---LNPFSDHGAL-LDPPTADVSARCVSMLAQLGER----R--DTSAVLDKALAYLENT
QEKDGSWYGRWGMNYIYGTWSVLCALNAAGVDPS-APPMRKAVDWLVSIQNSDGGWGEDGESYSL-GYERA-PSTASQTAWALMGLMAAGE--D-HPAVK
KGVTYLTSKQGS-GFWGEERFTAGFPRVFYLRYHGYSKFFPLWALARYRNLKSAN--
>tr|F8JII4|F8JII4_HYPSM Shc protein OS=Hyphomicrobium sp. (strain MC1) GN=shc PE=4 SV=1
---------------------------------------------------------------------------------------------IEGAIAA
AKNALLALQRDDGHFVFELEADATIPAEYVLMRHYLAEVDA-V---LEGKIANYLRRIQSEDGGWPLVHD-GSNISASVKAYFALKMIGVGIDEP---YM
KKARGWILSQGGASHSNVFTRNLLALFAVIPWTGVPVMPVEIMVLPRWFPFHLDKISYWARTVVVPLTVLNALKPQARN-PLV----AELFTIPPDVKVW
---------PK----EIF--GAIDRVL-RF----TEPH-PKSLRKKSIDKAVAFVDERNGEDGLGAIFPAMVLLVYDALYSKDH--PNYQTARGSIEKLV
VND-DEAYCQPC-LSPVWDTALSAHALMEVGDA-E--AASDRALQWLKPLQVLD-TVGDWAARPNVRPGGWAFQYANPHYPDTDDTAVVAMAMDRTLGRT
Q--QPDTTYREAISRAREWIVGMQSKNGGWGAFDADNTYEY---LNPFSDHGAL-LDPPTADVTARCLSMLAQLGDR----P--GNSYELDRGIAYLKRT
QEKDGSWYGRWGMNYIYGTWSVLCALNVAGVEPS-SSVVRKAVDWLLAIQNKDGGWGEDSESYTL-GYEAA-PSTASQTAWALMGLMAAGE--D-NPAVK
KGIAYLTSTQAS-GFWNEKRFTAGFPRVFYLRYHGYSKFFPMWALARYRNLKASN--
>tr|A0A0C6F5B1|A0A0C6F5B1_9RHIZ SqhC protein OS=Methylobacterium aquaticum GN=sqhC PE=4 SV=1
---------------------------------------------------------------------------------------------VERRVSA
ASRALTQLAHADGHWCFELEADATIPSEYILYHHFRASPPR-E---LEEKIAVYLRRTQSLHHGWALVHE-GFDMSASVKAYFALKMIGDPIDAP---HM
RRAREAILQRGGAAHANVFTRTLLALYGEVPWNAVPVMPVEVMLLPRWFPFHLDKVSYWARTVMVPLFVLQVKKPRAKN-PRI----RELFTQDPEIRRW
---------PS----PVF--AAIDDIL-RV----VEPF-PKKPRARALDKAVAFVSERNGEDGLGAIYPAIAVLMYEALYPEDH--PLVVTARSAVEKLV
VKE-HEAYVQPC-LSPVWDTALAAHALMEAGGQ-D--RQARAALEWLKPLQVLD-IKGDWAAKPDVRPGGWAFQYNNAHYPDLDDTAVVAMAMDRAQTRL
GPGEGGSDYTQSIARAREWIEGLQSRDGGFAAFDADNTYHY---LNPFSDHGAL-LDPPTADVTARCISMLAQLGET----K--ETSAPLARAVDYLLAD
QEEDGSWYGRWGMNYIYGTWSALCALNAAGHDPA-SVPVRKAVDWLVSIQNPDGGWGEDATSYKL-GYERA-GSTASQTAWALIALMAAGE--D-HPAVA
RGVNYLARTQGA-GLWGEEFYTGGFPRVFYLRYHGYAKFFPLWALARYRNLQRGN--
>tr|B7KXJ3|B7KXJ3_METC4 Squalene-hopene cyclase OS=Methylobacterium extorquens (strain CM4 / NCIMB 13688) GN=Mchl_2220 PE=4 SV=1
---------------------------------------------------------------------------------------------VERGVQS
ATRALTEMTQADGHICFELEADATIPSEYILFHQFRGTPRP-G---LEAKIGNYLRRTQSVHGGWALVHD-GFDMSASVKAYFALKMIGDDIEAP---HM
RAVRKAILQRGGAANANVFTRILLALYGEVPWAAVPVMPVEVMHLPKWFPFHLDKVSYWARCTMVPLFVIQAKKPRAKN-PRV----AELFVTPPDVRTW
---------PG----PIF--GGIDRVL-QK----TQDH-PKVPRQRAIDKAVAWVSERNGEDGLGAIFPAMVVLMYEVLYPPEH--PQVKIALEAIEKLV
EKE-DEAYVQPC-LSPVWDTALNSHAMLEAGGH-Q--ANARAGLDWLKPLQILD-IKGDWAEKPNVRPGGWAFQYANPHYPDLDDTAVVVMAMDRAQRQH
GLVSGMPDYSESIARAREWVEGLQSADGGWAAFDADNNHHY---LNPFSDHGAL-LDPPTADVTARVVSMLSQLGET----R--ATSRALDRGVTYLLND
QEKDGSWYGRWGMNFIYGTWSVLCALNTAGVDPQ-SPEIRKAVAWLIRIQNPDGGWGEDASSYKL-EFEPG-YSTASQTAWALLALMAAGE--D-DPAVA
RGVNYLVRTQGQ-GLWSEERYTAGFPRVFYLRYHGYPKFFPLWAMARFRNLKRGN--
>tr|M7YDU5|M7YDU5_9RHIZ Squalene-hopene cyclase OS=Methylobacterium mesophilicum SR1.6/6 GN=shc PE=4 SV=1
---------------------------------------------------------------------------------------------VERGVAQ
ATRALTALAHDDGHICFELEADATIPSEYILFHHFRGTVPG-D---LEAKIGNYLRRTQGRHGGWALVHE-GFDMSCTVKAYFALKMIGDDIEAP---HM
RRAREGILSRGGAANANVFTRFMLALYGEVPWRAVPVMPVEVMFLPKWFPFHLDKISYWARTTVVPLFVLQATKPRARN-PRI----QELFITPPEVRRW
---------PG----PIF--GFIDRIL-QL----VEDH-PRKRRQRAMEKARAWVSERNGEDGLGAIFPAMVVLMYEVMYRPDH--PQVRVACDAIEKLV
EKA-DEAYVQPC-VSPVWDTALASHALLEAGGP-E--AQARAGLDWLKPRQVLD-IVGDWAAKPKVRPGGWAFQYANAHYPDLDDTAVVVMAMDRAMHQH
GLVAGMPDYKASIARAREWVEGLQSEDGGWAAFDADNNHMY---LNPFSDHGAL-LDPPTADVTARVVGMLAQLGET----R--ETSRALDRGVNYLLND
QEEDGSWYGRWGMNFIYGTWSVLCALNAAGVDPA-DPRIQRAVSWLVRIQNPDGGWGEDASSYKI-AFEPG-SSTASQTAWALLALMAAGA--D-DPAVT
RGINFLTRTQGA-GFWKEERYTAGFPRVFYLRYHGYPKFFPLWAMARFRNLKRGN--
>tr|W3RK66|W3RK66_9BRAD Squalene--hopene cyclase OS=Afipia sp. P52-10 GN=X566_02650 PE=4 SV=1
---------------------------------------------------------------------------------------------LQASIAS
ATRALHAHQQSDGHWVFELEADATIPAEYVLFRHYLAEVDA-E---LERKIANYLMRIQGAHGGWPLFQD-GFDMSASVKAYFALKMIGHDIDAP---HM
KRAREAILANGGAIKSNVFTRFLLTFFGQLTWKSVPVLPIEIMLLPRWFPFHLTKVSYWARTTMVPLMVLAALKPLARN-PKV----DELFHEDPKIGTP
---------AR----ALF--NGIDAVL-RV----VEPY-PKTIRQRAIDRALAFIAERNGEDGMGAIFPPMVVMMYDALHDETY--PPRATTRRGIDKLL
FNG-DEAYCQPC-VSPVWDTALTCHALMEAGDE-E--RKAQRGLDWLKPRQVLD-VKGDWAERPDVRPGGWAFQYANAHYPDLDDTAVVVMAMDRARRAD
----GYKGFDGSIDRAVEWIEGLQSKDGGFAAFDADNLEHY---LNPFSDHAAL-LDPPTEDVTARCVSMLAQLGKT----V--ETSPAMARAVAYLRKT
QLAEGSWFGRWGLNYIYGTWSVLCALNAAGVSHK-DPAIVKAASWLKQIQNPDGGWGEDGESYKL-GYEPA-PSTASQTAWCLLALMAAGQ--D-DPAVA
KGVAYLMKTQNN-GEWDEARYTAGFPRVFYLRYHGYRKFFPLWALARYRNLQSTN--
>tr|J6UH59|J6UH59_9RHOB Squalene--hopene cyclase OS=Rhodovulum sp. PH10 GN=A33M_4201 PE=4 SV=1
---------------------------------------------------------------------------------------------LEAKIGK
ATEALLSYQQPDGHWVFELEADCTIPSEYVLLVHHLGEPDL-E---LERKIGVYLRRIQGAHGGWPLFHD-GFDISASVKGYFALKMIGDDPDAP---HM
RRAREAILAHGGASQVNVFTRIQLALYGQIPWTAVPVMPVEIMLLPRWSPFTLWKISYWARTTIVPLLVLQTLKPRAKN-PRV----DELFHENPQVGPR
---------AR----FLF--RGIDAVL-RG----IEPF-PRWPRKRAIEKAVAFCEERNGEDGLGAIYPPMAVMMYDVLFPPDH--PERAVARKAIDKLL
VKD-DEAYCQPC-VSPVWDTALTCHALLETGDD-R--ARARKGLDWLMPLQVLD-LKGDWAEKPDVRPGGWAFQYANAHYPDLDDTAVVAMALDRAYRKN
----PQARPDEAIDRAREWVVGLQSENGGFAAFDADNTYSY---LNPFSDHGAL-LDPPTEDVAARVVSLLAQLGEM----P--ETSEPLRRALAYLRET
QLADGSWYGRWGMNYIYGTWSVLCALNAAGLEAD-DPAVAKAAEWLIAIQNPDGGWGEDGTSYKL-GYEPA-PSTASQTAWALLGLMAAGR--D-APAVD
RGVAWLGRTQNA-GLWDEERFSAGFPRVFYLRYHGYRKFFPLWAMARYRNLKRAN--
>tr|A0A0E1BQM0|A0A0E1BQM0_BURPE Squalene-hopene cyclase OS=Burkholderia pseudomallei NCTC 13178 GN=shc PE=4 SV=1
---------------------------------------------------------------------------------------------LDAAVAR
ATDALLAAQQADGHWVYELEADSTIPAEYVLLVHYLGEPNV-E---LEQKIARYLRRIQQPDGGWPLFTD-GPNISASVKAYFALKVIGDDENAE---HM
QRARRAIHAMGGAEMSNVFTRIQLALYGVVPWYAVPMMPVEIMLLPQWFPFHLSKVSYWARTVIVPLLVLNAKRPVAKN-PRV----DELFKGAPVTGLL
---------PK----AFF--RAVDGVL-RL----VDGL-PRYTRERAIRQAVAFVDERNGEDGLGAIYPAMAVMMYAALYPEDH--PNRAIARRSIEKLL
VGE--EAYCQPC-LSPVWDTSLAAHALLETGDA-R--EAAVRGLDWLVPRQILD-VRGDWISRPHVRPGGWAFQYANAHYPDVDDTAVVAMAMDRVAKLD
---RT-DAYRESIARAREWVVGMQSSDGGWGAFEPENTQYY---LNPFSDHGAL-LDPPTADVSGRCLSMLAQFGET----S--ASSEPARRALDYMLKE
QEPDGSWYGRWGMNYIYGTWTALCSLNAAGLGHD-DPRVKRAAQWLLSIQNADGGWGEDGDSYKL-GYERA-PSTSSQTAWALLGLMAAGE--D-NPAVA
RGVDYLLGTQRE-GLWDETRFTAGFPRVFYLRYHGYRKFFPLWALARYRNLKRAN--
>tr|Q2IZC6|Q2IZC6_RHOP2 Squalene cyclase OS=Rhodopseudomonas palustris (strain HaA2) GN=RPB_1726 PE=4 SV=1
---------------------------------------------------------------------------------------------LDASIDA
ARAALLGYRRDDGHWVFELEADCTIPAEYVLLRHYLGEVDA-A---LEAKIAVYLRRTQGAHGGWPLVHD-GFDVSATVKAYFALKMIGDSIDAP---HM
AKAREAILARGGAIHVNVFTRFLLSMFGILTWRSVPVLPVEIMLLPMWAPFHLNKISYWARTTIVPLMVLAALKPRAVN-KLI----DELFLQDPQIGMP
---------AK----TLF--GSIDAVL-RV----IEPL-PKKLRSYAIGRAVAFIEERNGEDGLGAIYPPMAVMMYKVLYGEDH--PPRAITRRGIDLLL
VGE-EEAYCQPC-VSPIWDTSLTCHALLEAGGA-E--LPVRKGLDWLIPKQVLD-LKGDWAVAPNVRPGGWAFQYNNAHYPDLDDTAVVVMALDRARRDQ
----PSAAYDNAIARGREWIEGMQSDDGGWAAFDVNNTEYY---LNPFSDHGAL-LDPPTEDVTARCVSMLAQLGET----A--ETSSALARGVAYLRKT
QLAEGSWYGRWGLNYIYGTWSVLCALNAAGVAHQ-DPAMRKAVAWLASIQNADGGWGEDAVSYRL-GYESA-PSTASQTAWALLALMAAGE--D-HPAVA
RGVEYLKGTQTE-GVWDEQRYTAGFPRVFYLRYHGYSKFFPLWALARYRNLRATN--
>tr|J7JDD6|J7JDD6_BURCE Squalene-hopene cyclase OS=Burkholderia cepacia GG4 GN=GEM_5581 PE=4 SV=1
---------------------------------------------------------------------------------------------LDAAVAS
ATDALLAAQNADGHWVYELEADSTIPAEYVLLVHYLGEPNL-E---LEQKIGRYLRRIQQADGGWPLFTD-GPNISASVKAYFALKVIGDDENAE---HM
QRARRAIHAMGGAEMSNVFTRIQLALYGAIPWRAVPMMPVEIMLLPQWFPFHLSKVSYWARTVIVPLLVLNAKRPLAKN-PRV----DELFIDPPVAGLL
---------PR----AFF--RVVDHAL-RA----VDGL-PSYTRERAIRQAVSFVDERNGEDGLGAIYPAMAVMMYDVLYAEDH--PNRAIARKAVEKLL
VHE--EAYCQPC-LSPVWDTSLAAHALLETGDV-R--EAVLRGLDWLLPLQILD-VRGDWISRPNVRPGGWAFQYANAHYPDVDDTAVVVMAMDRAQKLK
---QT-DTYRESMARAREWVVGMQSSDGGWGAFEPENTQYY---LNPFSDHGAL-LDPPTSDVSGRCLSMLSQLGES----A--LTSEPARRALDYMLKE
QEPDGSWYGRWGMNYVYGTWTALCSLNAAGLTPD-DPRMKRGAQWLLSIQNKDGGWGEDGDSYKL-GFEQA-PSTASQTAWALLGLMAAGE--N-NPAVA
RGVDYLIARQNE-GLWDETRFTAGFPRVFYLRYHGYRKFFPLWALARYRNLKRAN--
>tr|B6JG70|B6JG70_OLICO Squalene--hopene cyclase Shc OS=Oligotropha carboxidovorans (strain ATCC 49405 / DSM 1227 / OM5) GN=shc PE=4 SV=1
---------------------------------------------------------------------------------------------LATSITR
ASRALHDVQQPDSHWVFELEADVTIPAEYVMMRHYFAEVDA-E---IEAKIAKYLRRMQNDNGGWSLFYG-HFDMSASVKAYYALKMIGDSPDAP---HM
KKAREAMLARGGASRANVFTRIMLALFGQVSWKAVPMMPVEIMLLPRWFPFHLTKVSYWARTVIVPLLVLMTLKPRAKN-PRI----RELFLEDPQVGPT
---------PK----TSF--DIIDRVL-RI----TDPF-PKGMRKRAIAKAEAFVTERNGVDGLGAIFPAMVIMMYDVLYPPND--PNRALARESVERLL
IKD-DEAYCQPC-VSPVWDTALAAHSMLESGEA-A--EAAKAGLDWLLPRQVLD-LKGDWADRPDVRPGGWAFQYNNAHYPDLDDTAVVVMAMDRVRRLD
----GTTKYDEAIARATEWILGLQSENGGWAAFDADNLEYY---LNPFADHGAL-LDPPTEDVTARCLSMLAQLGDT----L--ETSEPMRRGVEYLRKT
QLPDGSWFGRWGINYVYGTWSVLCALNAVGVPHD-DPMIAKAADWLESIQNEDGGWGEDGNSYKL-GYERA-ATTASQTAWATLALMAAGR--D-RDATQ
RGIDNLVQSQEA-GFWGEPYYTGGFPRVFYLRYHGYSKFFPLWAMARYRNLRSSN--
>tr|I3XGM0|I3XGM0_RHIFR Putative squalene--hopene cyclase Shc OS=Sinorhizobium fredii USDA 257 GN=shc PE=4 SV=1
---------------------------------------------------------------------------------------------LEMSIAS
ATEALLAYRHADGHWVFELEADSTIPSEYILLRHYLAEIDV-V---LEAKIGNYLRRTQGAHGGWPLVHD-GFDMSASVKSYFALKMIGDSVDAA---HM
VKAREAIRARGGAANSNVLTRFLLALYGVVSWRAVPVLPIEIVLLPIWSPFHLYKISYWARTTIVPLMVLAVLKPRAKN-PKV----EELFLQDTKVGMN
---------PK----LLF--RGIDGIL-RV----IEPH-PKKLRERAIASALAFTEERNGEDGMGAIYPSMAVMMYDALKDDHF--PPRAIARRAIDKLL
IGE-EEAYCQPC-LSPVWDTALTCHALQEVGGA-N--AKAKQGLDWLKPRQVLD-VKGDWAVAPNIRPGGWPFQYNNAHYPDLDDTAVVVMAMDRAQRHA
----GSKEYATAIARGREWIEGMQSRDGGWAAFDVNNLEYY---LNPFADHGAL-LDPPTEDVTARCVSMLAQVGEF----T--QSSKAVAEGIAYLRRT
QHAEGSWYGRWGLNYIYGTWSVLCALNAAGIDHQ-DPMIRKAVEWLVSIQSWDGGWGEDAISYRL-GYEQA-PSTSSQTAWALLGLMAAGE--E-HPAVA
RGVNYLKNAQTE-GLWDEQRYTAGFPRVFYLRYHGYSKFFPLWALARYRNLRSTN--
>tr|D6V590|D6V590_9BRAD Squalene-hopene cyclase OS=Afipia sp. 1NLS2 GN=AfiDRAFT_1773 PE=4 SV=1
---------------------------------------------------------------------------------------------LDDGIAS
ASRALLDVQKPDRHWVFELEADVTIPAEYILMRHYFAEVDT-V---LEGKIAKYLRRMQNDNGGWSLFYG-HFDMSASVKAYYALKMAGDSPDAP---HM
KKARETMLARGGAVKANVFTRIMLALFGQLEWKAVPVMPVEIMLLPRWFPFHLTKISYWARTVIVPLLVLMTLKPRARN-PLI----RELFIEDPKIGPT
---------PK----TSF--DIIDRVL-RL----ADPF-PKAMRQRAIRKAEEFVTERNGVDGLGAIFPAMVVMMYDVLYTPDD--PNRALARESVERLL
IKD-DEAYCQPC-VSPVWDTALAAHAMIESGQA-A--EAAKASLDWLLPRQVLD-VKGDWADRPDVRPGGWAFQYNNAHYPDLDDTAVVVMAMDRVRRMD
----GTTKYDDAIARAKEWILGLQSVDGGWAAFDADNLEYY---LNPFADHGAL-LDPPTDDVTARCLSMLAQLGDT----L--ETSEPMRRAVAYLRKT
QLADGSWFGRWGINYIYGTWSALCALNAAGVPHD-DPMIAKAADWLEAIQNADGGWGEDGNSYRL-GYERY-ATTASQTAWATLALMAAGR--D-RPATK
NGIDNLMQSQGV-GFWQEPDYTGGFPRVFYLRYHGYSKFFPLWAMARYRNLRSSN--
>tr|F7QL34|F7QL34_9BRAD Squalene--hopene cyclase OS=Bradyrhizobiaceae bacterium SG-6C GN=CSIRO_2281 PE=4 SV=1
---------------------------------------------------------------------------------------------LENSIEA
ASSAILDVRKADGHWVFELEADATIPAEYVLLRHYLAEVDS-V---LEAKIGNYLRRIQNDNGGWSLFYG-HFDMSASVKAYFALKMIGDKPDAP---HM
KKAREEILRRGGAIKSNVFTRIMLALFGVVTWRAAPMMPVEIMLLPRWFPFHLTKISYWARTVIVPLLVLMNKKPRARN-PLI----DELFLEDPKIGMT
---------AK----TGF--DLLDKIL-RV----VDPL-PKAPRQRAIDKAVAFVTERNGVDGLGAIFPAMAVMMYDLLYPKDH--PHYVLARQSIENLL
IKD-DEAYCQPC-VSPIWDTALTAHTMIEVGGE-K--ASAKAALDWLKPKQVLD-VEGDWIERPGVRPGGWAFQYNNAHYPDLDDTAVVVMAMDRARGTL
---NAGEKYDEAIARGREWIDGLQSKDGGWAAFDADNLEYY---LNPFSDHGAL-LDPPTEDVTARCVSMLAQLGET----V--ETSPALARGVEYLRRT
QLADGSWFGRWGVNYIYGTWSVLCALNAAGVDHK-DPVIAKGADWLISIQNPDGGWGEDGNSYKL-GYERS-ESTASQTAWATLALMAAGK--D-HPSVQ
RGIAYLIQFQGK-GLWTEPQYTGGFPRVFYLRYHGYSKFFPLWALARYRNLRNTN--
>tr|S3BBY3|S3BBY3_9ACTO Squalene-hopene cyclase OS=Streptomyces sp. HPH0547 GN=HMPREF1486_04726 PE=4 SV=1
---------------------------------------------------------------------------------------------VEKSLAL
AAEALRRGQDATGYWKGDFETSLIGESGEVILRHYLRLPPDE----TVAAAARTILSEQTSTGGWASYHEGPDELLLSVFCYVALRLAGHTPDEP---EM
RAAAASIRGNGGVEAVDNLLLAWLALIGLWPWRDIPLIPPEIVLLPPSFPGNIYQVGAAARGILVANSLFMARRPVVPT-GFI---R-------------
------------ARRPLV--RCATTLS-HW----YARHPVRPLRRRAVRKATRWLVRTERDGSWGGNWPQTAVMGLDAAYGQDH--PVVEAAMAGLDRYV
VHKDGHRRIEMW-TSVVMDTALALSASAMAGGPD-AEEAARPAVRWLLDNQVT--ELGDWAVTDDPQPGGWPYEFTNNANPDADDTAFAVAALRRVHPRG
---SD-PDVDAACERAGRWLLSQQGEDGGWAAFEPLRWRLP---GRKLARI-GF-LEAPSADITGHVLEALGADG-------RAG-TAAARRGIAWLRRN
QRPDGSWPGWWACYHLHGTSAAVTGLTACGIP--NDPAVRRACDWLVAHQRDDGGWGEDIRALHDWIGKG--TSTPSQTAWALLALIAGGRAG--SASVR
AGLDFLVRTQQDDGDWAEPWHTWVHHDGLYWRDSLLRLIYPVMAMSAYRAAVTGT--
>tr|D7BWI5|D7BWI5_STRBB Putative squalene-hopene cyclase OS=Streptomyces bingchenggensis (strain BCW-1) GN=SBI_00220 PE=4 SV=1
---------------------------------------------------------------------------------------------VERSLAL
AVGALRRRQDPAGYWKGDFETSLIGEAAEVILHRFLRLTDDA----VTTAAAKTILAEQSATGGWAAYHKGPDELLLSVFCYVALRLAGHDPDEP---AM
RAAAESIRTNGGVEAVDNPTLAWLALIGLWPWRDIPLIPPELVLLPSRFPGNIYQIGAAARGIVVANSLFMAHRPVTPA-GFI---K----------A--
-----------TARQRAV--RIATTLS-HW----YARHPIGFLRRRAIRKAAKWLVRTERDGSWGGNWPQTAVVGLDAVYQQDH--PVVESAMAALDRYV
VTRNGQHRLEMW-TSVVMDTALAMSAAAMTGDPG-ARSAAERAVRWLLTNQVT--ELGDWAVTKDPVPGGWPYEFANDANPDADDTSFAVAALRRLHPPG
---TH-AAVDDACARACRWMLSQQGKDGGWAAFEPMRWQLP---GRTLARI-GF-LEAPSADITGHVLEALGAEG-------QGH-TPAARRGVEWLRRN
QRPDGSWPGWWACYHLHGTSAAVTGLTACGVP--TDPTVTRACAWIVAHQQDDGGWGEDIRALHDWIGTG--DSTPSQTSWALLALIAAGRAD--SEPVR
AGLDFLIRTQQTDGDWDEPWHTWVHHDGLYWRDSLLRLVYPVMAMSAYRDRMGGS--
>tr|L8EUJ7|L8EUJ7_STRRM Squalene-hopene cyclase OS=Streptomyces rimosus subsp. rimosus ATCC 10970 GN=SRIM_13376 PE=4 SV=1
---------------------------------------------------------------------------------------------ARRAVRR
AADHLLSRRHTGGWWEEEFTTDVSYDAHDLFLRHVLGILDE-R--V-ATAGGRWIRSQQSADGSWPLVFGGAGHLGTTVQAYVALRLAGHRPDED---HM
GRCAAWVREQGGVAAAPLEAHVWLAMCGLWCWDDLPEIPPEIIALPTWAPLNIYAFSSIMRQALVSLGVISAYRPVQPV-PF-----DELFVPSDGPVRP
----------V----GVF--QRANTVL-RA----GRRI-PRAVRRIATNMCARWLLERETDGSWGACTPITTTLALHLHYAPDH--PVLKAALRFLDESA
SWPEDMRKLRTV-RSPVWDTGLAVTALLDAGL--DGHPALVGAADWLLARQSD--RPGDWTARPRLAPGGWAFQFHNRTYPDNDDTSEVVLALLRIEHP-
----DRARVDDAVRDAVRWCLGMQSADGGWAAFDVDNASAL---PGPFFDFGEYCVDAPTADITAHVVEMLAAAG-------MA-DDPRTRRAVQWLLGR
QEDDGAWFGRWGVNHVYGTGCVLPALIAAGTPCG-HPAVRRAVTWLTSVQN-DGGWGEDWESYADRVGRG--PSVPSQTAWALLALLAAGE--DS-AAVR
SGVRWLTGRQTDDGTWEEPEFTGLVPRAVACRYGYYRHVFPLMALGRYVHRRDAA--
>tr|G6XHR5|G6XHR5_9PROT Squalene-hopene cyclase OS=Gluconobacter morbifer G707 GN=GMO_10590 PE=4 SV=1
---------------------------------------------------------------------------------------------LEKVIQD
ALGVVGDQQQEDGYWDFELATDAGTSADYVLLEHYLG-VDP-E---RQQRIAVHLRRLQGHHGGWSLYHG-GFNLSSSVKAYFALKLMGDDPDTP---HM
RRARVAIIDHGGAARVNVFTRFQLALFGQVPWQAVPVMPVEVMLLPQSALFSIWNISCWSRTVMVPLMVLGALRPEAVK-LCD----RELFVRNPAVTDW
---------LR----QLF--RRGDRIL-RP----LVSR-PGKLHRQAIRAALDFIEPR-GPEGLGGTCSASSLVMYRALVADDD--PRVRTLWQALQTLL
TRKNE-THCQPF-MTSARDTALSGLAVLEASVTLSTMRALQKSARWLRDRQILE-KRGDWAVAPAARPGGWAFQGRNEYYPDLDDTALIGMLLQRL--D-
-----PLASRDAVEHAREWILGMQVADGGWETFDASNAHDL---LDPFAEQGLL-QDEPVADVTARCISFLCQAGDP----D---DRHAIGKALVFLRAA
QQPEGCWSGRWGVNYIYGTWTVLCALNVAGVPHS-DPMVKRAVTWLEDVQRQDGGWGEDCESYEGSGV-FR-QSIPSQTAWALLALMATGQ--D-SEATR
RGVSYLVSSRNR-GVWEEDHSTAIVPRRSYLRHDGYRQFFPLMALARYRNLTVNQ--
>tr|X0KZF3|X0KZF3_FUSOX Terpene cyclase/mutase family member OS=Fusarium oxysporum f. sp. vasinfectum 25433 GN=FOTG_17408 PE=3 SV=1
---------------------------------------------------------------------------------------------AEECLKP
AADYAYSLQKPDGHWLTELRSNISFTAQYVCLREIAGILRQSE---DRNHFRKWLLAQQNPDGSWSLAPG--GDLSISVEGYFALKLLGVSD-DK---AM
RLAKEFILSRGGLPLVI-ITQFLLAVFGLIKWDQIAQVPAELMLM--SP-VNIYAFAHWSRVTAVAMMVLRHHQPTFPL-PA-D-LMQELYPDVTDRLRF
---------YP---S-IA--ALADRAV-AL----MDPI-KTSLRAYSLSQCVQFMIKRT-ESGYASFWPANFILALYCQYEFKDP--AIKCLLHAIDFYI
WKDE-GMRNQVT-CGPSWDTALLLLGLSDSGFG-DER--LDKTVKWFKSTQILQ-IRGDY-E--GLLPGGWAFQYNNDWYPDTDDTVTILLAILSWKPTE
----L---TSDCCIRTIQWLLGMQCTNGGWGCYDVNNENYF---LNPFGQGNEF-YDAPVPDVTARILEGFGYVLDLDNSALIFKIRESCANAISYLYST
QDATGAWKSRWHVNYINGTGSALQALALFDDTFDNSRMIQRGLVWMKSMQNADGGWGETLRTYRD-AGLGD--STPSQTSWALLGLLSHLD--SEDESIR
RGIKYLVRTQVPSGTWEQEGYVSAFPNITWLDYTSTRHAYPMMALGRYVHKFQEK--
>tr|T0KEL5|T0KEL5_COLGC Terpene cyclase/mutase family member OS=Colletotrichum gloeosporioides (strain Cg-14) GN=CGLO_09991 PE=3 SV=1
---------------------------------------------------------------------------------------------ATKCIQQ
AAEHAYDQMKPDGHWYLEVRSSISFTVQWLCIRQILGMLSED----EADKFRRWLLSQQNDDGSWGLAPSDWGDVSTTVEAYFGLKLLGTNN-SK---PM
RKARAFVLRHGGVAKVV-LTQLVLALFGIIGWKDMAQVPAELMAL--SP-VNIYSFSYWSRVSAVPVMLLKHHQPIFPL-HPGADEEDELFLNTLDTLKS
---------IP---Q-AC--TLIDKAA-SV----VEPV-RSMLRTYCLDQCVQYIVNHD-AGGFGSLTISNFVVGLHAAFPASHP--VMGHLTRAMEDAL
WEDA-GLRMQVT-IGPVWDTALMTLGLLETGLA-DDR--TDLSIKWFKDHQILK-THGDY-L--ASLPGGWSFQYCNEYFPDNDDTLVCLFAIVMRNPKE
----I---NSACGSRALNWLLSMQGGDGGWGAYDIDNTSKV---ANPFADGVEF-FDPSVPDITGRVLEVLGYIITEPTPAVLERVREACRKGLEYIAKS
QDLTGTWWARWHVNYLNGTSSVLCALPYLQSVEQAGILISEPISWIKAVQNVDGGWGESLGTYRD-AGRGL-ISTPTQTAWAVMALLSHLP--HTDPAIE
RGVQYLLRTQIGSVTWDQEAYVSGFPNTLWLDFGCMRHGYPMVALGRYLHACKQR--
>tr|N4ULS5|N4ULS5_COLOR Terpene cyclase/mutase family member OS=Colletotrichum orbiculare (strain 104-T / ATCC 96160 / CBS 514.97 / LARS 414 / MAFF 240
---------------------------------------------------------------------------------------------ATQCVKQ
AAEHAYSQMKPDGHWYLEVRSSISFTVQWICIRQIVGPVSPE----EADKFRKWLLSQQNEDGSWGLAPADWGDVSTTVEAYFGLKLLGTPE-SK---AM
RKARAFTLRNGGVARVV-LTQLVLALFGIVAWKDMAQVPAELMAL--SP-VNIYSFSYWSRVSAVPVMLLKHHQPIFSL-SVGSDEEDEIFVNPLERLTS
---------IP---E-AC--TIIDKAA-SV----VEPL-RSMLRKHCLDQCVQYIVNHD-AGGFGSLTISNFVVGLHASFPASHP--VMGHLTRAMQDAL
WEDD-GLRMQVT-IGPVWDTALMTLGLLETGLA-DGR--TDQTIKWFKDHQILK-THGDY-V--ASLPGGWSFQYCNEYFPDNDDTLVCLFAIIMRNPRE
----I---NSACGARALNWLLAMQGGDGGWGAYDIDNTSRI---ANPFADGVEF-FDPSVPDISGRVLEVLGYILADPTPAVYQRVREACRRGLRYLSRS
QDLTNTWRARWHVNHLNGTSSVLCALPHLKSVEQEGILVEEPVAWIKAVQNPDGGWGESLGTYRD-AGRGL-VSTPSQTAWAVMGLLSHLP--HTDPAIE
RGVQYLVRTQVRSVTWDQDAYVSGFPNTLWLDFGCMKHGYPMVALGRYLHACKQS--
>tr|B6K412|B6K412_SCHJY Terpene cyclase/mutase family member OS=Schizosaccharomyces japonicus (strain yFS275 / FY16936) GN=SJAG_03360 PE=3 SV=1
---------------------------------------------------------------------------------------------LERTVKS
AYEALAKDQQDDGHWIYELEADVTIPAQFILLEHTLD-IDE-E---LEQKIANYLRRCQSEHWGWPVYYG-GFNISASVQAYFALKMTGEDINAP---HM
VRAREAILAHGGPEYANVFTRIQLSLFGEASWLATPFMPVEIMLLPRWMYFSIWNMSYWSRTTVAPLLIVADLKPKAIN-PRV----PELFPTPPDVKTW
---------IH----HVF--KFIDTAI-RP----FTRF-PSFLHKKAYKAALDFIEPRNGVDGLGAIYPPMSAVMYRALIPDDD--PRAATNWEALKGLL
IKERE-AYCQAC-VSPVWDTALSGHALMEASF--GTEKLIDRAAHWLRAHQVLN-VVGDWAINPNLQPGGWAFQYGNDYYPDVDDTAVAAMLLHRQ--N-
-----LPENEEALDRARKWIIGMQSSNGGWGAFDIDNDKQI---LNPFADHGAL-LDPPTADVSARCISLLAELGHP----E---DRPVIERGIKYLRKE
QEEDGSWFGRWGTNYIYGAWSVLCAFNASGVPHD-DPSVLKCVNFLKSVQREDGGWGESCETYEGAG-VYT-ESLPSQTAWAVLGLMASGR--T-DPAVK
RGIVWLIQHQQD-GEWAEEPFNAGFPRMFYLHYLGYKQFFPLLALARYRHMEKSG--
>tr|B3RCD7|B3RCD7_CUPTR Shc protein OS=Cupriavidus taiwanensis (strain R1 / LMG 19424) GN=shc PE=4 SV=1
---------------------------------------------------------------------------------------------LDRGIDR
ALDALLHQQRPDGHWVYELEADATIPAEYVLMVHYLGEPDR-D---LEARIARYLRRIQNPDGGWPLFHQ-GSDISASVKAYFALKMAGDDPQSA---PM
QRARQAIHAMGGAEATNVFTRTLLALYGVLPWKAVPMMPVEIMLLPRWFPFHLSKVSYWARTVIVPLLVLNSLRPQARN-PRV----NELFVGNCHVGLP
---------PR----TVF--RGLDALL-RL----AEPL-PRTLRRRAIAAAQRFVRERNGEDGLGAIFPAMAVMMFDVLVPPED--PARAVARRSIERLL
EHG-DEAYCQPC-LSPVWDTALATHALLETGEA-R--QAAGRALDWLRPLQVLD-LRGDWAVRPLVRPGGWAFQYANAYYPDVDDTAVVAAAMDRFMRAH
---HAPGRYGEAVARATEWIVGMQSGNGGWGAFEPENTHLY---LNPFADHGAL-LDPPTADVSARCLSMLCQTGAT----P--ANSEPAARALRYLLAE
QMPDGSWFGRWGTNYIYGTWSALCALNAAGLPPE-APELCRAVAWLARIQNADGGWGEDGSSYRL-GYEPA-PSVASQTAWALLALMAAGA--Q-HPAVA
RGIDYLLRTQQP-GLWHEPRFTAGFPRVFYLRYHGYARYFPLWALARYRNLQRGL--
>tr|G8ARS8|G8ARS8_AZOBR Shc protein OS=Azospirillum brasilense Sp245 GN=shc PE=4 SV=1
---------------------------------------------------------------------------------------------VSDAVAE
ATDALIRRQQADGHWVFELEADATIPSEYLLLHHILD-IDP-E---LEAGLAAFIRGRQGKDGGWPLFFG-GMDISCSVKAYFALKAAGDSPDAP---HM
RRAREAILARGGAARCNVFTRILLAQFGQIPWRAVPAMPVEVMNLPPWSPFHISRISYWSRTVVVPLLVVMAHRLRARN-PRI----AELFTEPPEVRNW
---------HS----TLF--RALDAAL-HA----VEPR-PANGRQTAIDRAVRFVTERNGEDGLGAIFPAMVVLMFHCLMPPDH--PDAATARRALRGLV
R---GRVYCQPC-LSPVWDTAIICNALLETGNP-QARAAARRGADWLVDRQILD-VEGDWAWRPGLASGGWAFQYNNAHYPDTDDTAMVVMALQRLD---
-----TERYGEPIRRARDWIVGMQSRNGGWGAFDAENQHDF---LNPFADHGAL-LDPPTSDVTARCVMMLARLGE-----G--RDTVPTRRGLTFLERE
QESDGSWFGRWGTNYVYGTWSALEALNAAGVPHS-AVAVQRAAQWLLAHQRPDGGWGEDGASYWANRGEGA-VSTASQTAWALLGLMAAGK--N-HPAVD
RGVDYLLSARDA-GLWSEEPFTAGFPRVFYLKYHGYAASFPLWALARYRALRV----
>tr|J8NXT2|J8NXT2_BACCE Squalene-hopene cyclase OS=Bacillus cereus VDM022 GN=IKM_01990 PE=4 SV=1
---------------------------------------------------------------------------------------------VHEEIER
RTTALQTMQRQDGTWQFCFEGALLTDCHMIFLLKLLGR----D---EIEPFVKRLVSLQTNEGTWKLYED-KGNLSATIQAYAALLASERYKEAM---NM
RRAEMFIKEHGGVSRAHFMTKFLLAIHGEYEFPALFHFPTPILFLQDDSPLSIFGLSSSARIHLIPMMICMNKRFVEKL-LP-----NHIAGGG-G--W-
----------F----PLF--QSFLGDVK-------IS--PLSLHHKGYEEVERFMKERDENGTLYSYASATFIYALLALHSIQS--PIIEKAVTGLKSYI
WKMD-GSHLQNS-PSTVWDTALLSYSLQEAKVTN-ENKMIQRATEYLLQKQQT--KKVDWSVASSLVAGGWGFSDVNTTIPDIDDTTAALRALARSR-G-
----N-DRVDDAWGRGVEWVKGLQNNDGGWGAFERGVTSKL---LSPIENASDMITDPSTPDITGRVLELFGTYAPN----E--LLEEQKKKAIKWLMDV
QEQNGSWYGKWGICYIYGTWATMTGLRALGVPST-HPALKKAASWLEHLQHEDGGWGESCQSSVEFISLP--FSTPSQTAWALDALISYYD--E-TPIIR
KGISYLLAQSTM----NEKYPTGGLPGGFYIRYHSYGHIYPLLALAHYVKKYRK---
>tr|J9HEP4|J9HEP4_9BACL Squalene-hopene cyclase OS=Alicyclobacillus hesperidum URH17-3-68 GN=URH17368_1239 PE=4 SV=1
---------------------------------------------------------------------------------------------VDAAVKS
ACVQLLQHQGADGAWTDCFDTGMMPNAQTVISLYLIGYRDA-T---WTAPLVRAIRKHQREDGSWGLFPG-AGDLSTTVECFYALELMKAWPDDA---PR
VRAKAWIARHGGVRRCRNLTKMFLAVGGEIPWSWLPSPWLYTLMFMKGSPFSIEDIATFTRVHVPAMLVLSLYRYRSRY-AA-----RELVNCDERWDD-
-----------------------------------DRP-RTKLASWCAERCLVFLRTHGQDGTLAGYHSSTWLFALHALIDFDA--PIIRCAIASMRQNL
VEEHGYAHQQTT-NAHIWNTALACRVLLDAGIPE-SHPQLQKAKSYLLAKQQV--E------RTGRPDGGWGFSSNNENHPDCDDTVACLDALRGFM-Q-
----P---SAIPINQGVSFLLSMQNRDGGWSAFEHNCDKRW---LEPANDMRRAMCDPSTADITGRVVAFLLRRRVL----S--PTDSSIKRAIAWLQAN
QLRDGSWYGRWGTTYLYGTWCAVQALVAANLPAS-SPSLMRALRWLLSVQKADGSFGERCESDMLYSPAF--TGQPTQTAWGLDALLHLYDT---TDTAV
KAVNWLLDHR-TADGWFDTCPNGAFPGALYITYHIYPKVWPTSALLHFQRSIEGK--
>tr|A0A094K878|A0A094K878_9BACL Uncharacterized protein OS=Thermoactinomyces sp. Gus2-1 GN=JS81_04530 PE=4 SV=1
---------------------------------------------------------------------------------------------VQAMIHR
LKKELIQKQNPDGTWPFCFENGIGTDAYYVLLHQVLKRPDP-G---TLAPVLERILDKQTGDGTWKAFPDKEGNVSATLDASLALLYSGVKPDDP---SL
KRARDFLLSRGMETKAGSLTQVVLALLGHRSWSRITKLPVEFFLLPAASPVNFFDFVGYARVHIAPVMLASDQDFYIHL-KGR----EDWLPSSFRYMER
---------MH----DLL--PAV-ETT--------AYS-KKNVHQRALYWGENFLLSREEDGTLYSYMTSTFIFALLSLYPPDH--PLIQKAMEGLDRMI
FPLQEGAHLQEA-TSTVWDTSLVMTALQNAGLSP-GHGVIQKGRNYLLLKQHT--SCGDWCLNRYAIPGGWGFSDTNTINPDVDDTVQCLHAIAPAV-RE
----G--WAQDEWKRGLQWLLSMQNRDGGWPAFERNTNKMW---LKPARNEKRVWGDPSTADLTGRVLHFLGSELGW----T--IDRPEVRRAWSWLYHH
QNSDGSWFGRWGVSYIYGTWAALKGLAAVGVPET-HVSVQKGIRFLLSKQRPDGGWGESCYSDAEFVPLS--FSTPVQTAWALDALIAYHDP---TPAIE
KGMACLLEMM-EKRGEEWSYPAGGLSGQFYVYYHSYPYVWSLMAMTHYLQKYS----
>tr|F5SAI4|F5SAI4_9BACL Squalene--hopene cyclase OS=Desmospora sp. 8437 GN=sqhC PE=4 SV=1
---------------------------------------------------------------------------------------------AANGANQ
MIGELTRQQQTDGRWIFCFESGVMSDAYMLLLYEIFGTGRR-E---YREGMAQRLLSL-SDNGIWRSYPDKGGSVTATLEASIALVAAGYKLSDP---LI
QNSQAFVREQGGMAAAGSLTRVAMILTGLHRWPDNSQIPIKLFLLPWWFPINFFDFVGFTRVHVAPILLASNRKFSVRL-PRP----LALWNGEGGSHD-
---------------QLE--GKIDEFL-PH-----LRL-GGRLDRLVEERGLRFILDREPDGTLYSYFSTTFIFALMAMYRRDH--PVILRAISGLERFY
LPVKGGLHLQET-TSTVWDTALISYALQEAGMTA-DDPVIQKAGGYLLSRQQT--RLGDWALNPGVAPGGWGFSDINTINPDVDDTSYNLRALGPLA-RM
---NR--QVYQSWARGARWELSMQNRDGGWSAFEKNTDKKW---PKPKSDAQTVWTDPSTADLTGRTLEWVGNHLGW----K--RGHPVVDRAASFLVKN
QEPDGSWFGRWGINYIYGTWAALTGLTSVGFRRG-HPAIDKGVQWLLSVQHEDGGWGESCNSDVVYVPLK--MSTPVQTAWAVDALVAVHDP---TPAIE
AGVHRLLQLC-EHPGEPAEYPTGGLSGQFYIYYHSYRYVWPLTALSHYRRKYAEK--
>tr|R4KP48|R4KP48_9FIRM Squalene-hopene cyclase OS=Desulfotomaculum gibsoniae DSM 7213 GN=Desgi_2958 PE=4 SV=1
---------------------------------------------------------------------------------------------VLLRIRD
LTDLLVNSQEKDGAWYYCFEAGLLTDAYMIILLRHLSMNDE-T---LIHKLAYRIASKQEPTGAWKVFYDPEGNLSATIECYYALLLAGYKKTDP---EM
IRAREFILAKGGLSAAGSYTKVMLAITGHYPWGNAPYLPVEMVLLPTWAPINFFDFNGYARVHVAPISICASKNYAHKL-PGA----SDLFPSSSKVP--
------------S--SLL--KAIEKHI--------KKI-LNEIRDLAIKELERFMLAREWDGTLYSYFTTTLIFALLALYDKRH--PVITKAVKGLKAMA
CRTI--YHLQTA-TSTIWDTGMIAYALQEAGLPP-HHPAIEKATLYLLAKQHT--KYGDWLINPQGRPGGWGFSHSNTINPDVDDTAYTLRALYRQAMNN
---SE--TYGHAWRAGLEWLLSMQNDDGGWPAFEKNTNKKW---PDPMPEAKSVLTDPSAADLTGRALEFLGNYAGM----S--HRQEQVQKAVQWLVKD
QRSDGSWYGRWGVVYIYGTWAAVTGLTAVGIAPQ-HHAVKKAVNWLLSIQNPDGGWGESCLSDSVYTPLG--FSTPSQTAWALDALIAAGLE---SPAVL
RGIEALLHLT-EKNGIEASYPTGGLPGGFYIHYHSYRYIWPLLALSHYLRI------
>tr|R9LCZ1|R9LCZ1_9BACL Squalene-hopene cyclase OS=Paenibacillus barengoltzii G22 GN=C812_02306 PE=4 SV=1
---------------------------------------------------------------------------------------------IRGEIQR
LTEELIERQELDGTWRFCFENGISIDACTIILFRTLNIDKE-D---LIRQLHDRILAAQEPEGCWRWYHDKEGHLSATAEAYYALLYSGYSPEDE---PI
QRAKRYILDRGGIGHVSLLTKAILAATGQRDWPTSLLIPIELLLLPEALPLNFYDFSGYSRVHLVPLLIMADRNFRARS-KRP----SELFIDARSEQDP
----------L----EPL--KLIQSAL--------AHL-PQRIRHAAVNRAEQYMLDRESDGTLYTYASCTVVFALLALYEPQH--PVIQRAVEGLSQMK
FAVDRYVTIQNS-PSTVWDTALISYALQEAGVSP-IHPAIQRAADYLRERQHH--RPGDWQINSGIVPGGWGFSETNTFVPDVDDTTAALRALSAFH-AD
---DC--EVLESWNRGLNWVWSMQNNDGGWPAFEKNTNKEM---LTAIEGAKSAAIDPSEADLTGRTLEFLGNFAKL----S--VRQDWVARGADWLLSH
QEGDGSWYGRWGICYIYGTWAALTGLMAVGMPAD-HPGIAKAADWLRRIQNPDGGWGESCRSDQVYVPLQ--ASTPSQTAWALDALIAVHDP---TPEIE
RGVARLIAML-HEEDWPSTYPTGGLPGYFYVHYHSYRYIWPLLALSHYVNKYGDG--
>tr|H0U5A4|H0U5A4_BRELA Squalene/oxidosqualene cyclases family protein OS=Brevibacillus laterosporus GI-9 GN=sqhC PE=4 SV=1
---------------------------------------------------------------------------------------------AELEIKR
IIHLLQKAQSVDGAWRYCSESGPLTDAYMIILLRTLMIDDE-E---LIRSLADRITIRQEKNGAWKLFHDEEGNLSATIEAYYALLFSGYSKTDE---HM
QLAKKFILTKGGISEASMLTKLLLALTGQYPWSGYFQIPVEIILLPHWLPINFFDFVGYARVHIAPILVVADRKFVMKT-RRP----SDLRKNDLPAL--
------------GNHAFL--NTILDGF--------KNL-PSQIHNMALRQAERYILEREPDGTLYSYFTSTFIFALLSLYSANH--PVITRAISGLKAMT
CLTNGHLHIQIA-TSTVWNTALLAHAMQGTGVSA-SEPTVQNTGRYLLSRQHH--KYGDWMINPFVLPGGWGFSDINTINPDVDDTTAALRAISKLR-ET
---DP--TFHHSWDRGLNWLLSMQNADGGWPAFEKNTDKRI---VNPFDAADAVSTDPSTADLTGRTLEFLGNNAGF----T--IGHPQIQKGVKWLLSN
QEANGSWYGRWGISYIYGTWAAITGLMAVGVSSE-HPAIQKAVQWLLKIQNEDGGWGESCKSDIVYVSLG--ASTPSQTAWGVDALISVFQP---IPVIE
RGIQFLIDSE-KNQDWTLSYPTGGLPGGFYFHYHSYQYIWPLLALGNYKKKY-----
>tr|A0A0D1XYT1|A0A0D1XYT1_ANEMI Strain NCTC 7096 contig_46, whole genome shotgun sequence OS=Aneurinibacillus migulanus GN=TS65_10725 PE=4 SV=1
---------------------------------------------------------------------------------------------VETEINR
LITVLKNQQTSDGSWRYCLESGPMTDAYMIILLRTLNIHDE-D---FIRRLTERVIYRQEKNGAWKLFHDEGGNLSATVEAYYALLFSGYCKKAE---HM
QAARQFILSRGGITEVSMLTKVMLALTGQYPWPQHTLIPLEILLLPLTFPLNFFDFVGYARVHVAPILIVTDQKFFIKT-QKP----SDLYVNNSTSM--
------------NLQSIL--KFIKSWT--------ENL-PKHIHNVAIRRTEQFMLDREPDGTLYSYFSSTFIFAFLALYSDKH--PIILHAIKGLKTLT
CKSNEPIHIQNA-TSTVWNTALLSYALQDAGVPY-SSMTIQKAGQYLLSRQHK--KYGDWIINPNITPGGWGFSDINTINPDIDDTTAALRAISKLA-KT
---SP--IYRQAWEYGVNWVLSMQNDNGGWPAFEKNTDKEI---VKPIDGADSTSTDPSSADLTGRTLQFLGHDVGL----N--VHYPNISRGIRWLMKH
QEEDGAWYGRWGISYIYGTWAAITGMNAVGISPN-HPAIQKAVRWLLKIQNADGGWGESCRSDTVYVPLG--FSTLSQTAWAIDALIAVSKS---IPAIE
RGIQYLIVAG-DKFDWTTTYPTGGLPGGFYFHYHSYRYIWPLLALSHYKLKYLGN--
>tr|V6M1T0|V6M1T0_9BACL Squalene-hopene cyclase OS=Brevibacillus panacihumi W25 GN=T458_16575 PE=4 SV=1
---------------------------------------------------------------------------------------------VESEINR
IVHLLQGNQSPDGAWRFCLESGPLTDAYMIILLRSLHIDDE-E---FISGLAQRIAALQMENGMWKLFHDEEGILSATVEAYYALLYAGHSRDEE---HM
QAARQQILAKGGLSQTSMLTKLLLSLTGQIPWDAHVPIPIEAMLLPRWSPLHFFDFVGYARVHIAPILILTDRKLVIQT-GRP----SELRIPRTA----
---------------YFQ--KRIEDVI--------RFL-TAQIHQEALNQAKHFMLKREADGTLYSYLTSTVIFALLALYPKSH--PIITRAVAGLKAMA
CHRNGQIHMQDA-TSTVWDTALLTHALQVSGVSA-SHPMVQKAGRYLLSRQHD--KYGDWVLNPAAIPGGWGFSDSNTINPDIDDTTAALRAISPMQ-KT
---GM--AYQRAWQRGLNWLLSMQNDDGGWPAFEKNTNKQI---LSPIEGADAVSTDPSTTDLTGRTLEFLGNHAGL----N--VRNRNMQKAVSWLLRN
QEENGSWYGRWGICYIYGTWSAVTGMIAVGIPKE-HPAIQKAVQWLLRIQNHDGGWGESCNSDIVYVPLR--ASTPSQTAWAVDTLIAASSP---TSPMM
RGIQFLLGND-AESDWTLSYPTGALPGDFYFHYHSYRYIWPLIALGHFQKKYG----
>tr|A0A090Z1Y3|A0A090Z1Y3_PAEMA Squalene-hopene cyclase OS=Paenibacillus macerans GN=shc PE=4 SV=1
---------------------------------------------------------------------------------------------VGREIGR
LTDELVRRQQPDGTWRYCFENGTAMDVSVIVLLRSLSAGSE-E---LIRSLHDRILAAQQPEGCWRWFEDREGNLSATVEAYYALLFSGYSPEDE---PI
RRARNYIQAAGGIEMAGLLTKALLAATGQRKWPVALSIPLEILLLPPSFPVSFFDFSGYSRVHLVPLLIMADRDFSLKT-PHP----SDLYGGGRGDEE-
---------------DLL--AHIQAGI--------GRL-PQRIHQAAVKKAEQYILEREADGSLYTYASCTVVFALLALYDRRD--PLITHAVDGLAAMR
CSAGGEVTIQNS-PSTVWDTALIAYALQEAGLSE-DHAAIRKAAAYLRSRQHR--KAGDWQINPGVAPGGWGFSDTNTIIPDVDDSTAALRAIHSLA-GR
---EP--ACLEAWNRGLNWVLSMQNDDGGWPAFEKNTNKEM---LTAIDGAKAAAIDPSEADLTGRTLEFLGNFARL----D--ARHEFIRRGADWLIRH
QEADGSWYGRWGICYIYGTWAALTGLKAAGLASD-HDAVAQGVSWLLSVRNPDGGWGESCRSDREYVPLR--ASTPSQTAWALDALIAVHDP---TAEID
QGIARLIAML-HEDGWTASYPTGGLPGYFYVHYHSYRYIWPLLALGHYRKKYGGD--
>tr|C0ZG69|C0ZG69_BREBN Putative squalene-hopene cyclase OS=Brevibacillus brevis (strain 47 / JCM 6285 / NBRC 100599) GN=BBR47_38010 PE=4 SV=1
---------------------------------------------------------------------------------------------VQQEINR
IQAFLLQRQQEDGTWRFCLESSPMTDSHMIILLRTLGIHDE-R---LMEKLTAHITALQHDNGAWKLYPDQEGHLSTTIDSYYALLLSGKYKNEP---RM
ALARSFILEKGGLTQANMLTKFATALTGQYQWPSHFLVPVEIALLPPSFPVSFYDFVGYARVHLAPMMIVADRNYVKKP-DNP----SDLYADTPIRG--
------------LYPSFL--ATIHDSL--------QQL-PGQLHKLALRRLEQYILAREPDGTLYNYSTSTFIFALLARFSPKD--PLIQKAMQGLTGSV
YDYENGAHLQLA-TSAVWDTALLTFSLQKSGLSP-THPAIQKANRYLLRKQQH--TYGDWKINPNGKPGGWGFSDYNTMNPDIDDTTAALRSLRLLA-RT
---DV--TAATAWKRGLEWLLSMQNDDGGWPAFERNTDADF---IRPIEGADTVSTDPSSADLTGRTLEFLGNYAGR----T--LTDLHVEKGVRWLLKH
QESDGSWYGRWGIAYLYGTWAAITGLMAVGFSPT-EPAIQKAVAWLVANQNPDGGWGESCQSDLKYVPLG--ASTPSQTAWAIDALIAVSSP---TAELQ
RGIRYLLTHN-QANDWTTRYPTGGRPGGTYFAYHSYRWIWPLLALSHYQVKYANT--
>tr|S9U6S3|S9U6S3_PAEAL Squalene-hopene cyclase OS=Paenibacillus alvei TS-15 GN=PAALTS15_15661 PE=4 SV=1
---------------------------------------------------------------------------------------------VDDEIER
LTKTIIEQQRQDGSWRFCFENGTSVDAYVIILFRLLNVPNE-E---LIRQLHDRILAAQQPDGCWRLFADEEGNLSASVEAYYALLYSGYSMADE---PI
QRARRYILSKGGLGKVNIMTTAILAATGQRKWPASISIPLEVVLFPTYFPINIYDFSGYSRVHLIPMLIMGDKQFSMTS-AHP----SDLYVRTMDED--
---------------EIQ--NIIKEGL--------KLL-PRYIHEAATTKAEQFMLTREADGTLYSYANSTIIVALLALYDQQH--PLITRAIQGLTDMQ
FRY-GTTTMQNS-PSTVWDTALLAYTLQEAGIAA-DHLTIRRAAAYLLSKQQD--KTADWSINPDTIPGGWGFSETNTINPDVDDTTAALRAIRRLS-NT
---NS--TYLDSWNRGLNWVISMQNNDGGWPAFEKNTKNEF---LTALDGAKSAAIDPSEADLTGRTLEYLGNFAGL----D--TRHKFIKRGTHWLVSH
QEKDGSWYGRWGVCYIYGTWAALTGLAAVGLPAS-HEPLQKGARWLLDIQNPDGGWGESCQSDRLYVPLG--ESTPSQTAWALDALIAVQTP---TPEVD
QGIHRLIALL-HEDDCKSIYPTGGLPGYFYSHYHSYRYIWPLLTLSHYKKRYGNS--
>tr|A0A0C2UPH4|A0A0C2UPH4_9BACL Cohnella sp. VKM B-2846 B2846_33, whole genome shotgun sequence OS=Cohnella sp. VKM B-2846 GN=SD71_20570 PE=4 SV=1
---------------------------------------------------------------------------------------------MGEEIGR
LADQLSGLQAEDGTWRFCFENAVSTDAYMIIVLRTLEIADE-P---LIRRLRDRLLAAQHADGSWRVYPDDEGNLSATVECYYSLLYSGYNESDP---PL
AKAKKFILSKGGLQNIGVLTRVILAATGQYPWHPSHMIPLEFILLPSSFPISIFDFSGFARVHIVPILVLADRQFSIRT-NLP----SELKVNRSG----
----------------AV--GFFDDRI--------GNF-PRQLHADAIKRAERFMLEREPDGTFYSYATCTIIFALLSIYDKRH--PTISNAVQGLRSML
CRSGQQIFLQNS-PSTVWDTALLSHALQEAGVPV-DGQVIRASTSYILSKQHR--KFGDWKINPKTIPGGWGFSDSNTLNPDVDDTTAALRAIKNRT-AA
---DT--SYRQAWNRGLNWVLSMQNDDGGWPAFEKNTDQEL---LTPMKEAKSAAIDPSTADLTGRTLEFLGNSAGL----G--SRHSFIRKGTDWLTNR
QEKDGSWYGRWGVCYIYGTWAALTGLTSVGVNGD-NSAVRKGTRWLLTVQNADGGWGESCKSDRMYTPLG--ESTPSQTAWALDALIAVHAP---VPEMN
KGVQRLISLL-HEENWRTAYPTGGLPGIFYSHYHSYRYIWPLLALSHYKNKYCV---
>tr|V9G609|V9G609_9BACL Squalene-hopene cyclase OS=Paenibacillus sp. JCM 10914 GN=JCM10914_1394 PE=4 SV=1
---------------------------------------------------------------------------------------------VEAEIYK
LTDFLIQKQQRDGSWHFCFENGVAVDAYVLMLFRILDIQNE-T---LVRQLHDRVMAEQQPGGDWRWYYDHEGNLSASIDAYHALLYSGYSPEDE---HM
VRARRYIQSQGGLAKAGVLTKAILAATGQRTWPKSIVIPVELVLFPDYMPINLYEFSGYSRVHLIPMLIMADLNFSITS-EWP----SDLQISRHIEE--
---------------EII--DSIRVGI--------RRL-PRSIHEAALRKAERFMLDRESDGTLYSYASTTVVLALLALYDKQH--PVIMRAVQGLTSLQ
FRLNKATTIQNS-PSTIWDTALITYALQESGIVE-DHPSVRRAADYLLARQHD--KTADWSVNRGTVPGGWGFSESNTLNPDVDDTTAALRAIHGLS-YN
---DPDQVYQHAASRGLNWVISMQNKNGGWPAFEKNTDKEM---LTAIDGAKSAAIDPSGADLTGRTLEYLGRFCGF----S--TEHLFIKRGAEWLISN
QEQDGSWYGRWGICYIYGTWAAVTGLRATGIPAD-HPTIRKAADWLLHIQNPDGGWGESCTSDRLYVPLG--ASNPSQTAWALDALISVQSP---SPAVI
KGMGTLIELL-HVNDWRTEYPMGGLPGSFYTHYHSYRYIWSLLALGHYKQKYGKQ--
>tr|E5WKT9|E5WKT9_9BACI Uncharacterized protein OS=Bacillus sp. 2_A_57_CT2 GN=HMPREF1013_03072 PE=4 SV=1
---------------------------------------------------------------------------------------------TVSSMNN
LITLLRKDQSPDGSWNYPFETGISTDAYMIILLKTLEIHDE-K---LIQGLAARIISKQEENGAWKIFEDKDGNATATLEAYYGLLYSGYIKEDP---RM
KAAREFILEHGGMESVNVFTKIMLSSTGQYKWPESFPVPVEIMLLPLSFPFNFYQFSVYGRVNLAPILILAEKKFSIKT-KNP----SDLLLTRSGV---
---------------SLL--SFIKEGV--------EDL-PEQFHSLAMDRANKYMLEREPDGTFYSYFSSTFIFALLSLYSKDD--PIVKNAVAGLKSLR
TDIDGLPHMQYA-NAGVWNTSLINAALQLAGLSP-EDSAVKKANTYLLQRQHD--QFGDWVINPNALPGGWGFSDVNTRNPDIDDTTVSLRAIARSV-ED
---NS--KNQEAWNRGTQWLLSMQNDDGGWPSFERNTENPW---LDPIEKGEYIFGDPTSADLTGRTLEFLGNYTNL----P--DHDPAVQNAINWLLNN
QEQNGSWYGRWGVCYIYGTWAAVTGLIASGMSKD-HPSIQKAADWLKGFQNEDGGWGESCLSDSKYVPLH--ASTITDTAWALDALITAEDP---TEEIQ
KGIHCLVHSI-DKEDWTTAYPKGAMAGSFYIHYHSYRYIFPLMALAHYHRKFG----
>tr|F5LIR7|F5LIR7_9BACL Putative squalene-hopene cyclase OS=Paenibacillus sp. HGF7 GN=HMPREF9413_4437 PE=4 SV=1
---------------------------------------------------------------------------------------------VAHAIHN
LSEWLLGKQEKDGTWKFCYDNGISTSAYLIILLRTLETDDE-A---LIRRLHDSIVRNQQPDGSWKLYADKDGNLAASVEAYYALLFSGYSDSSP---SL
VNARAFIRSRGGITGVNVLTRVILAATGQIPWPAAYSIPLEFLLLPASAPLSFFDLSAYARVHLAPVLLMADRNFSVRT-SRP----SALGVRRDEGKSG
---------ASSGSVGLL--AAIQAGI--------SQL-PGQLHGSAVKKAERFMLEREPDGTLYSYASSTCVFALLSLFERRH--PTIAQAVKGLKAML
CVSEGRLLMQNA-PPTVWDTALIAYALQEAGVRP-EAPGIRKAASYLLAKQQR--KIGDWGRVSHPVPGGWGFSPSNTRNPDVDDTTAALRAVKFLR-SE
---GT--AGREAWNRGLYWIISMQNQDGGWAAFEKDTDEKL---LTPMEGAKHAAIDPSTADLTGRTLEFLGSTAGL----G--VKHVWIRRGADWLVAN
QEKDGSWYGRWGICYLYGTWAALTGLAAVGLEPD-HPAVAKGVRWLLSVQNPDGGWGESCASDIVYESLG--ASTPSQTAWALDALIAVHPP---SAAID
RGIQRLVAAL-DERDWTSLYPTGGLPGSFYNTYESYRYIWPLLALSHYRNKYGEK--
>tr|I3E8W8|I3E8W8_BACMT Sporulenol synthase OS=Bacillus methanolicus MGA3 GN=sqhC PE=4 SV=1
---------------------------------------------------------------------------------------------TEAMIRR
IVDKLKSDQAPDGSWQYPFETGISTDAYMIILLRTLEINDE-E---LIRKLTERIISKQEENGAWKLFYDGDGNLSATVEAYYSLLYSGYYKDDK---RL
RTAERFILSKGGIENSHMFTKIMLSLTGQYPWPPLFPIPVEIVLLPLSFPVNFFDFSVYGRVNLAPILIVADKKYSKRT-KRP----SNLFHSRADF---
---------------SLF--TIFEEGM--------KSF-PMHIHSLAIERAKQYMLDREPDGTFYGYFSSTFIFALLSLYSKKD--PIILKAVTGLKEMK
CLINGHTHMQYT-TATVWNTSLISFALQKAGITP-SEPVVSGANRYLLQRQHD--KYGDWMVSPNVLPGGWGFADINTLHPDIDDTTSSLRAISKLV-RQ
---EP--HFQRAWERGINWLFSMQNDDGGWPAFEKNVNKKI---LNPIEGGKFLLTDPSTADLTGRTLEFFGAYTNL----S--KNHPSMKRGVNWLINN
QEKDGSWYGRWGICFIYGTWAALTGLIASGVSSH-HQSIQKAVNWLYKIQNHDGGWGESCKSDIMYIPLG--ASTLIDTAWAVDALIAAADP---TPGIQ
AGIKFLLKSF-EKNVWTISYPKGVIAGGFYIHYHSYRYIFPLLALSHYKQKFQD---
>tr|A0A089JK05|A0A089JK05_9BACL Squalene-hopene cyclase OS=Paenibacillus sp. FSL R5-0345 GN=R50345_14930 PE=4 SV=1
---------------------------------------------------------------------------------------------VDNEIER
LAAFLIDQQKEDGTWLFCFENGIVIDAYVIILFRILNVQNE-A---LIRALHDRILAQQQPAGFWQLYRDEAGNLSTSVEAYYALLYSGYSVTDE---PI
QRAKRYILSKGGIGKVSILTKVILAVTGQSKWPLAISIPLEVLLFPSYFPINYFEFSGYSRVHLTPMLIMADQRFSFPT-ANP----SDLIDTRIENE--
---------------ELQ--RVMQSGL--------DRI-PRYIHEVARTKAEQFMLQRESDGTLYSYGTSTIIFALLALYDQQH--PIITKALDGLTAMQ
CRS-SKTTIQNS-PSTIWDTALITYALQEAQVPD-HHLAIKRATSYLLSRQQN--KTADWSINPDTAPGGWGFSESNTINPDVDDTTAALRAIRSLS-TS
---QP--SYLESWNRGLNWVLSMQNKDGGWPAFEKNTNKEM---LTAIDGAKSAAIDPSEADLTGRTLEYLGNFAGL----D--TRNDFIERGTKWLIQH
QEKDGSWYGRWGVCYIYGTWAALTGLQAVGLPLE-HDTMQKGVKWLLSIQNSDGGWGESCQSDRLYVPLG--ESTPSQTAWALDALIAVHPP---TSEME
KGILRLIASI-NQVDWKSSYPTGGLPGNFYSNYHSYQYIWPLLTLSHYRKKYGKA--
>tr|W7L7G9|W7L7G9_BACFI Squalene-hopene cyclase OS=Bacillus firmus DS1 GN=PBF_09127 PE=4 SV=1
---------------------------------------------------------------------------------------------ITAGMKR
LIAALKRGQSSDGSWNYPFETGISTDAYMIILLRTLEMHDE-K---LIQGLAARILSKQEENGAWKLFRDQDGNANATLEAYYGLLYSGYIKEDP---RM
KAAGNFIREHGGLESANVITKIMLSTTGQYPWPESFPIPVEIMLLPLSFPFNFYQFSVYGRVNLAPILILTEKKFSIKT-ENP----SDLLLTRA-----
---------------SFL--SFIKEGV--------EDL-PEQLHSLAMDRAKDYMLEREPDGTFYSYFSSTFIFALLSLYSKDE--PVIKNAVAGLKSLR
TDIDGLPHIQYA-NSSIWNTSLINTALQLAGVSP-DDPAVRKANTYLLMRQHD--QLGDWAINPHGKPGGWGFSDVNTLNPDVDDTTASLRAIARSV-ED
---SS--EYQDAWDRGIQWLVSMQNDDGGWPSFERNTENPW---LAPIEKGKYMFGDPASADLTGRTLEFLGNYTNL----P--AADPLIKNAVNWLLDH
QEQDGSWYGRWGICYIYGTWASVTGLVAAGHS-N-HPSVRKACGWLKKIQNEDGGWGESCLSDSQYVPLN--ASTLTDTAWAVDALIAAEDP---NEQIQ
KGIQYLLNSI-EKEDWTTAYPKGAMAGSFYIHYHSYRYIFPLMTLAHYRGKFGE---
>tr|A0A0A2TND9|A0A0A2TND9_9BACL Squalene-hopene cyclase OS=Paenibacillus sp. MAEPY2 GN=P364_0132295 PE=4 SV=1
---------------------------------------------------------------------------------------------VDEEIRR
MTTSLLQQQQQDGSWHFCFENGTVIDAYVIILFRILDVQNE-A---LIRQLHDRILNEQQPNGCWRLYPDEEGNLSASVEAYYALLYSGYSSTDE---PI
QRAKRYIQSKGGIGKVSILTKAILAATGQMKWPLSIMIPLEILMFPTYFPINYFEFSGYSRVHLTPMLIMADLRFSLTI-PDP----SDLTDLRIVDE--
---------------EMQ--DDIQTGR--------SRL-PRHIHDTARTKAEQFMIEREADGTLYSYASSTIVFAFLALYDKQH--PLITKAVTGLTAMQ
CRSSGKTTIQNS-PSTVWDTALITYALQEASITD-DHKAIQRAASYLLSRQQD--KTADWSINPNTVPGGWGFSESNTLNPDVDDTTAALRAIRSLS-TT
---LP--NFQESWNRGLNWVLSMQNKDGGWPAFEKNTNKEV---LTAIDGAKSAATDPSEADLTGRTLEYLGNFAGL----D--TRHEWINRGTKWLIRN
QEKDGSWYGRWGVCYIYGTWAAITGLTAVGLPAS-HDTVQKGTQWLLSMQNSDGGWGESCHSDRLYVPLG--ESTPSQTAWALDALIAVQPP---TPEVN
QGILRLIASI-RENDWRTSYPTGGLPGNFYSHYHSYTYIWPLLTLSHYRKKYWIS--
>tr|A0A089HNA9|A0A089HNA9_PAEDU Squalene-hopene cyclase OS=Paenibacillus durus GN=PDUR_09960 PE=4 SV=1
---------------------------------------------------------------------------------------------IDEAIDH
LTSTLIRQQHPDGAWHFCFENGTAIDAYVIILFRTLNIQSE-A---LIRQLHDRILAGQQPEGCWKLYSDEEGNLSASIEAYYALLYSGYSLTDE---PI
QRAKHFIQSKGGLRKVSTLTKAILAATGQIKWPASISIPLEVMLLPPSVPINIFEFSGYARVHLAPMLIMADRHFSMKT-AQP----HDLHVNRINGE--
---------------EAL--DSIRSGL--------NRF-PRSIHDAAVKKAEQFILQRESDGTLYSYASSTIIFSLLALYDKHH--PLITDATQGIKAMH
WSF-GKTTIQNS-PSTVWDTALVAYAMQESGVPD-DHIAIRRAAVYLLSRQHH--KTADWTINPDIPPGGWGFSETNTINPDVDDTTAALRAIKSLS-RT
---DP--SCRESWNRGLNWVLSMQNEDGGWPAFEKNTNKEI---LTAIDGAKSAAIDPSEADLTGRTLEYLGNFAGL----D--NRYKFIQRGTQWLIKH
QEKDGSWYGRWGICYIYGTWAALTGLRATGISSN-HEALQKGAKWLLSIQNADGGWGESCSSDRLYVPLG--DSTPSQTAWALDALIAVHPP---TAEIN
KGIYRLIASL-QEDKWMTTYPTGGLPGSYYSHYHSYRYIWPLLTLSHYRKKYEPG--
>tr|G7W4M4|G7W4M4_PAETH Squalene-hopene cyclase OS=Paenibacillus terrae (strain HPL-003) GN=HPL003_17185 PE=4 SV=1
---------------------------------------------------------------------------------------------VDEGIRK
LRDFFMRQQHQDGSWHFCFENGVTMDAYVMILFRILDIQNE-E---LIRRLHDRILAEQQPEGCWRWYRDQEGNLSVSIDAYYALLYSGYSPTDE---SM
ERARHYIQLQGGPGKSSILTKAILAATGQRKWPASIFIPLEIILFPAYMPINLYEFSGYSRIHLIPMLIMADRNFSIST-DKP----SDLFDSRYDDE--
---------------EIT--ENIRIGL--------SRL-PRYIHEAALNKAEQFMLNRESDGTLYSYASSTIVFALLALYDKQH--PLILKAVQGLTEMQ
YRFGK-ATIQNS-PSTIWDTALISYALQESGVVG-DHETVQRSAAYLLSRQQD--KAADWSVNPDTVPGGWGFSETNTLNPDVDDTTAALRSIHSLS-RT
---DP--KYRDSSTRGLNWVMSMQNKDGGWPAFEKNTNKKM---LTAIDGAKSAAIDPSGADLTGRTLEYLGNCCGL----D--MRHDFIKRGVNWLISH
QEKDGSWYGRWGICYIYGTWAALTGLEAARLPAD-HAAIQKGAEWLLQIQNSDGGWGESCTSDRVYMPLG--ESTPSQTAWALDALIAVQPP---SAAVN
RGIYKLVELL-QNDDWPTAYPTGGLPGNFYSHYHSYRYIWPLLTLSHYKKKWVGS--
>tr|J2I1W3|J2I1W3_9BACL Squalene-hopene cyclase OS=Brevibacillus sp. CF112 GN=PMI08_03301 PE=4 SV=1
---------------------------------------------------------------------------------------------VREEISR
IQSVVLHSQQQDGSWRFCLESSPTTDAHMIILLRTLGIDDE-R---LIDGLTARITALQQENGAWKLYPDAEGNLSTTVDCYYALLLSRRYKKEP---RM
ARARAFIRGKGGLSEANLLTKFAAALAGQYKWPAHFLVPVEIALLPPSSPISFYDFVGYARVHLAPMMIVADRKYVNVT-ADP----SDLYVNPSIPG--
------------VYPSFL--SSIHEYV--------LRL-PGLLHELSLRRLEQFILAREADGTLYNYSTSTFIFALLARYSLRD--PLIAKAMSGLRDSV
CQTAEGAHLQLA-TSAVWDTALLSHALQQSGLPA-SHPAIQRANRYLLKKQQH--TYGDWKINPGGVPGGWGFSDYNTMNPDIDDTTAALRALLSQS-RL
---DK--ATAAAWKRGLDWLLSMQNDDGGWPAFEKNTDSPL---ISPIEGADTVSTDPSSADLTGRTLEFLGRYAGY----K--ENDAPVQKAVRWLLAR
QEIDGSWYGRWGIAYLYGTWAALTGLMAVGVSPA-HPAVQKAVDWLTRQQNADGGWGESCHSDEQYVPLG--ASTPSQTAWALDALIAVHPP---TPAIE
RGIDYLSRQS-QAADWTTAYPTGGRPGGTYFAYHSYRWIWPLLALSHYQSKYASA--
>tr|W4DEC7|W4DEC7_9BACL Squalene-hopene cyclase OS=Paenibacillus sp. FSL H8-237 GN=C171_05622 PE=4 SV=1
---------------------------------------------------------------------------------------------VDEEIER
LTTFLLQQQKDDGSWHFCFENGIVIDAYMIILFRVLNQQNE-T---LIRQLHERILDAQQREGFWQLYKDEAGNLSTSVEAYYALLYSGYSITDE---PI
QRAKRYILSKDGLGKVSILTRVILAATGQSKWPLAISIPLEVLLFPSYFPINYFEFSGYSRVHLTPMLIMADRRFSITT-AHP----SDLMETRLDDE--
---------------ELQ--DVIQMGL--------SRL-PHYIHEAAKNKAEQYMLQRESDGTFYSYASSTIVFALLALYDRQH--PIITQAIQGLTALQ
CQS-HKTTIQNS-PSTIWDTALISYALQEAQIPV-DHKGIKHAAAYLLDKQHH--QTADWSINPDTVPGGWGFSESNTINPDVDDTTAALRAIRSLS-TI
---HP--SYLESWNRGLNWVLSMQNNDGGWPAFEKNTNKEM---LTAIDGAKSAAIDPSEADLTGRTLEFLGNFAGL----N--TQHEFIKRGTKWLIQH
QEKDGSWYGRWGVCYIYGTWASLTGLQAVRLPIN-HDTLQKGVKWLLSIQNSDGGWGESCHSDRLYVPLG--ESTPSQTAWALDAIIAVQPP---TAAVE
KGIQRLITSI-HEEDWKTSYPTGGLPGNFYSNYHSYRYIWPLLTLSHYRKKYGQG--
>tr|A0A0A2TAY8|A0A0A2TAY8_9BACI Squalene-hopene cyclase OS=Pontibacillus yanchengensis Y32 GN=N782_18020 PE=4 SV=1
---------------------------------------------------------------------------------------------FYKERDR
LIEKIKSLQTESGSWHLCFENSLLTDAFTIILYKTLKVKDD-D---FIAALAERIASKQLSNGAWKLYHDDDGNVSLTINAYYALLFSGFKKKDP---LM
KKASSFIKENGGLMRANTMTKLMLAVTGQLPWSNLPSIPIELLLIPKSFPLSFYDFVGYARVHLAPIVILMNSQFRLTT-KDP----SDLLLYDSR----
---------------FLK--GWINDSL--------SYL-QEKTNDKAVSKAKKYMVEREPNGLLYGYFLSSFVFALLALYRKQD--PLIKKALAGIKTLI
CSPKHSIHIQNS-PSTVWDTALLSSALQLVGVDH-TDEHIQQANYYLLSRQHF--RYGDWSFNPNTLPGGWGFSDVNTMEPDVDDTTAALRSLKNLV-YE
---QN--KYRSEWNRGLKWVLSMQNDDGGWPAFEKNTNKQL---LTPIDGADVASVDLSTPDLTGRTLQFLGDYASL----P--KDHPQIKSGVNWMLDH
QRTDGSWYGRWGICYIYGTWAAVTGLKASGLSDA-HPSIKLAKEWLERIQNEDGGWGESCRSDQEYIPLK--ASTPSQTAWALEALIATSPP---TKVID
RGMTALLNSL-KQKDWTYSYPTGALPGQFYIYYHSYNYVWPLQTIAKYCNKYLT---
>tr|A0A023DK02|A0A023DK02_9BACI Putative squalene--hopene cyclase OS=Geobacillus caldoxylosilyticus NBRC 107762 GN=GCA01S_076_00100 PE=4 SV=1
---------------------------------------------------------------------------------------------ISGELSR
LVVTVKREQAPDGSWRYPFETGISTDAYMIILLRTLEINDE-D---LIRKLVERIESRQEGNGAWKLFYDGEGNVTTTVEAYYALLYSGYRKTDP---HM
QAAKQRILEMGGIENVHMFAKFMLAMTGQYRWPKFFPIPVEFLLLPPSFPLHFFDISMQGRANLTPLLILTDNKYYRKT-RKP----SDLFLSRADGE--
---------------SFL--SYLK-----------QSL-PRQIHAAAKQRAIQYMLQREADGTFYSYFSSTFIFALLSLYPKDH--PIIVKAVNGLKTFR
CSINGHTHMQYT-TATVWNTALASYALQEAGVPP-SDAAVEKANRYLLSRQHY--RYGDWVVNPYSLPGGWGFSNINTINPDVDDTTASLRAIYSQA-SK
---ET--LFRHAWDRGLRWLLSMQNNDGGYGAFEKNVNKRL---FHPIQGAEFLLTDPSTADLTGRTLEFFGTYANL----T--KDHPAIARGIKWLIDH
QEKNGSWYGRWGICYIYGTWAAVTGMIAVGVPPT-HPANQKAAKWLLSIQNSDGGWGESCKSDSAYVPLR--ASTATHTAWALDTLIAVFDP---IPEIQ
AGIQFLLQSI-RKEDWTASYPTGGMAGGFYIHYHSYRRVFPLLTLSHYEKKFGSL--
>tr|A0A0A0E6S2|A0A0A0E6S2_9BACI Squalene-hopene cyclase OS=Bacillus niacini GN=NP83_02050 PE=4 SV=1
---------------------------------------------------------------------------------------------TSKGIDW
LIKTLRSDQSPDGSWDYPFETGLSTDAYMIILLRTLEINDE-E---LIKELAERIVSRQDTNGSWKLFYDREGNLTATVESYYALLYSGYYKKDK---RL
QNAKKFILSKGGIEKVSMFTKVMLALTGQLEWPSFSHLPVEIILLPLSFPINFYSFSVYGRANFTPMMVLADKKLSIKT-DKP----SDLLDGRLDG---
---------------SLF--SFIGDGV--------KNL-PQQLHKLAIQRAKKYMLDHEDDGTFYSYYSSTFIFALLSLYKKSD--PIILKAIEGIKSMK
CVIDGHPHLQYT-TADVWNTSLIGYVLQEAGISP-ADPMVGAANQYLLKRQHT--KFGDWVINPASLPGGWGFSDINTINPDVDDTTASLRSISRMG-SG
----H----HDAWSRGINWLLSMQNDDGGWAAFEKNTDTKL---FEPIEKAEFILTDPSCADITGRTLEFFGNYTNL----S--KDHSSIKKGVKWLLNH
QEGDGSWYGRWGICYIYGTWGAVTGLSAVGIPGS-DESIQKAVDWLYRIQNSDGGWGESCYSDNKYVSLG--ASTLIHTAWALDALISVSDP---TLAIR
KGISYLLENL-QKEDWTTAYPKGGMAGAFYIHYHSYRYIFPLLALAHYRKKFET---
>tr|A0A077J3C5|A0A077J3C5_9BACI Uncharacterized protein OS=Bacillus sp. X1(2014) GN=HW35_02125 PE=4 SV=1
---------------------------------------------------------------------------------------------IINGLNW
IVDKLRKEQSPDGSWNYPFETGISTDAYMIILLRTLEINDE-E---LIRGLCKRILNKQEKNGAWKLFYDKEGNLSTTLEAYYSLLFSGYYKEHK---SL
QAAKRFILAKGGLEKVSIFTKIMLAITGEYKWPARPPLPIEVILLPQLFPINFYSFSVFGRANLTPIMILTTKKFSIRT-KHP----SELRLKRDEE---
---------------SIL--SSIEDGV--------KRL-PKELRNMALKRAEKYMLDRELDGTFYSYFSSTFIYALLSLYKKSD--PTITRAIEGLKSMK
CKIEGFPHMQYT-TANVWNTSLISFALQSAGISP-EDPMIKKANDYLLKRQHH--KFGDWVINPNSLPGGWGFSDVNTINPDVDDTTASLRSISRIS-PP
----E----LAAWKSGISWTISMQNDDGGWPAFEKNTDSKL---LTPLEKGEFLLIDPSCADLTGRTLEFFGNYTNL----S--RKHPIIQRGINWLLNN
QQKNGSWYGRWGICYTYGTWAAITGLKAVGISSS-HPSIQKAVKWLYSIQNHDGGFGESCYSDMKYIPLR--YSTLTHTSWVLDALISVSDP---TPAIR
KGMVYLLDSL-DKNDWTTTYPKGGMGGAFYIHYHSYRYIFPLLALSHYQKKY-----
>tr|A0A089IHY4|A0A089IHY4_9BACL Squalene-hopene cyclase OS=Paenibacillus sp. FSL H7-0737 GN=H70737_14335 PE=4 SV=1
---------------------------------------------------------------------------------------------VDNEIER
LTAFLIDQQQQDGSWHFCFENGIVIDAYVIILFRILNVQNE-A---LIRQLHDRILAEQQSAGFWQLYRDKDGNLSTSVEAYYALLYSGYSVTDE---PI
LRAKHYIQSKGGIGKVSILTRVILAATGQSKWPLSISIPLEVLLFPSYFPINYFEFSGYSRVHLTPMLIMADRRFSIST-ANP----SDLIDTRIEAE--
---------------ELQ--DVIQTGL--------SRL-PRYIHEVARTKAEQFILRRESDGTLYSYATSTIVYALLALYDQQH--PLITNAINGLTAMQ
CRS-SKTTIQNS-PSTIWDTALIAYALQEAQIPD-HHLAIQRATSYLLTRQQH--KTADWSINPDTTPGGWGFSESNTINPDVDDTTAALRAIRSLS-IT
---QP--SYLESWNRGLNWVLSMQNKDGGWPAFEKNTNKEM---LTAIDGAKSAAIDPSEADLTGRTLEYLGNFADL----D--TRNEFIGRGVKWLIQH
QEKDGSWYGRWGVCYIYGTWAALTGLQAVGLPLE-HETLQKGANWLLSIQNSDGGWGESCHSDRLYVPLG--ESTPSQTAWALDAIITIQPS---TAAVE
KGIERLIMSI-HEEDWKTSYPTGGLPGNFYSNYHSYRYIWPLLTLSHFRKKYGQR--
>tr|N0AU77|N0AU77_9BACI Squalene-hopene cyclase OS=Bacillus sp. 1NLA3E GN=B1NLA3E_12450 PE=4 SV=1
---------------------------------------------------------------------------------------------VEKEIQR
LIDIFRKDQSFDGSWAYPFETGVATDSYMIILLRTLEIDDE-E---LIQELAERLLSKQEKNGAWKLFHDGDGNITSTTEAYYSLLYSGYYETDD---RI
QAAKRFILARGGLDNIHQLAKIMLALTGQYKWPTFFPLPVELMLLPVTFPLNFFSFSVYGRANLSPIMILANKKFKIRT-EKP----SDLLLGRMDN---
---------------SLH--SAIYQGV--------KSL-PERLHKQAILSAKQYMLDREPDGTFYSYFSSTFIFALLALHRKDD--PIIVKAVDGLKAMK
TKINGHTHIQYT-TANVWNTSLISYALQETGLSP-SDSMVEKANDYLLSRQQN--KYGDWRIAPNGLPGGWGFSDVNTINPDVDDTTATLRAIARKV-KV
---DA--RYRIAWGKGIQWLVPMQNDDGGWSAFERNINQNW---LKPIKKVEFFLSDPSTADLTGRTLEFFGSYTKL----T--KNSPMINKGLESLLQQ
QEENGSWYGRWGICYLYGTWAAVTGLKAIGVSSK-HHSIKKAMKWLESVQNSDGGWGESCKSDNNFVPLG--TSTLTDTAWALDALIAASSP---TTNIQ
AGIQYLLQNI-EKDDWTTSYPAGGMAGGFYIHYHSYRYIFPLITLAHYQKRFKIE--
>tr|A0A0E0TCC4|A0A0E0TCC4_GEOS2 Squalene/oxidosqualene cyclase OS=Geobacillus sp. (strain Y412MC52) GN=GYMC52_1950 PE=4 SV=1
---------------------------------------------------------------------------------------------VADERSA
LIDALKRSQSVDGSWRFPFETGISTDAYMIILLRTLGIHDE-P---LIQALVERIESRQDANGAWKLFADGDGNVTATVEAYYALLYSGYRKTDS---HM
QKAKARILEVGGLERVHLFTKVMLALTGQHSWPRRFPLPLVFFLLPPSFPLNMYDLSVYGRANMVPLLVVAERRYSRKT-DNP----SDLAASRN-----
---------------ALW--SYVK-----------RSL-PAWLHRAAEQRAVRYMLEHEPDGTLYSYFSSTFIFALLALYPKDD--PHIARAVRGLRSLR
TEIDGHTHMQYT-TASVWNTALASYALQEAGVPP-TDRTIEKANRYLLSRQHI--RYGDWAVNPYGVPGGWGFSDVNTMNPDVDDTTAALRAIRRAA-AK
---ET--AFRHAWDRANRWLFSMQNDDGGFAAFEKNVGKRF---WRPIEGAEFLLMDPSTADLTGRTLEYFGTFAGL----T--KDHSAIARAIDWLLDH
QEADGSWYGRWGICYVYGTWAAVTGLSAVGVPID-HPAMQKAVRWLLSIQNDDGGWGESCKSDGAYVPLG--ASTPVHTAWALDALIAAAEP---TPEMK
AGVRALVRML-HHPDWTASYPVGGMAGAFYIHYHGYRYIFPLLALAHYEQKFGPF--
>tr|A0A0C1DUT8|A0A0C1DUT8_9BACI Squalene--hopene cyclase OS=Bacillus thermotolerans GN=QY97_3878 PE=4 SV=1
---------------------------------------------------------------------------------------------TSEGIQR
LIDRLRKDQTPDGSWAYPFETGLSTDAYMIILLRTLEIHEE-E---LIQGLVSRLMDKQEKNGAWKLFYDPDGNVTATVEAYYALLYSGYVKSDP---KL
RAARRFILAKGGVERINIFAKIMLAITGQYKWPACFPVPVEVMLLPPSFPVHFYQFSVYGRVNLAPILLLAEKKFSLRT-SRP----SDLLLDRSDH---
---------------PIL--SSIEQEV--------KRL-PSRLRSLAVDRAKTYMLEREPDGTLYSYYSSTFIFALLSLYKKED--PLIRRAVSGLTAMK
TEIGGQPHMQYT-TANVWNTSLINSALQLAGVPL-HDPMVEKANRYLLERQHY--KFGDWAINPAGVPGGWGFSHINTVNPDMDDTTASLRSIARGV-TD
---HS--AFRRAWDRGVQWLLSMQNDDGGWAAFEKNVKGRW---IHPVEKGEFIFSDPSSADLTGRTLEFFGNYTNL----P--NDHKGMKRAARWLISN
QESDGSWYGRWGICYIYGTWAAVTGLQSAGFSAD-HPSVKKAAAWLRSIQNRDGGWGESCRSDSEYVPLG--KSTLTHTAWALDALIAAEGP---SPAVQ
KGVQFLLGSL-ENTDWTTDYPKGGMAGSFYIHYHSYRYIFPLLALSNYRRAFG----
>tr|K6DLH2|K6DLH2_BACAZ Squalene-hopene cyclase OS=Bacillus azotoformans LMG 9581 GN=BAZO_01982 PE=4 SV=1
---------------------------------------------------------------------------------------------ITTRLNE
LIEKVRNDQSPEGYWNYTFETGISTDCYMIILLRSLEIDDE-N---LIKGLSERIVRKQQENGAWKLFHDPNGNLSDTIGAYYALLYSGYYKNEP---RL
RLARQFIKTNGGIDKSHMLTKIMLALTGQYKWPVFFPIPIEMILLPVSFPINFYSFSVYGRVNLAPIMILANKKFSIKT-SKP----KDLFIHREEEHG-
---------------SLS--SLINQGI--------KSL-PSHVHQLATEYTKQYMLSREPDGTLLSYFSSTFIFALLSLISKSD--PIIVNAVKALKSMI
RDINGLPHMQFT-TANVWNTSLLTYALQESGISS-DDIVVKKANNYLLKKQHY--KYGDWVINPSALPGGWGFSESNTIHPDVDDATASLRSIARNV-RK
---DW--RCRQAWDRGIQWVLSMQNDDGGWPAFEKNTNSKI---VHPVEKAEYFLTDPSCADLTGRTLEFLGMYTNL----S--KTHPSIKRGVDWLLKN
QERNGSWYGRWGICYIYGTWGAVTGLRAVGILPT-DPMISKAVKWLKEIQNSDGGWGESCQSDLNYIPLN--ASTLTHTAWAVDALIAASDP---TRSIQ
RGVDYLLENI-HKEDWTTNYPKGGMAGDFYIHYHSYRYIFPILTLAHYRKKFS----
>tr|W4BHP6|W4BHP6_9BACL Squalene-hopene cyclase OS=Paenibacillus sp. FSL R5-808 GN=C169_03867 PE=4 SV=1
---------------------------------------------------------------------------------------------VEEEINK
LIDFFIQRQHQDGSWHFCFENGITLDAYVIILFRILEIQNE-E---LIRELHDRILAEQQPEGCWRWYHDEGGSLSATIDAYYGLLYSGFSWSDE---HM
EHTRRYIQSQGGLGKSSVLTKAILAATGQRKWPASILIPLEIILFPAYLPINLYEFSGYSRIHLIPMLIMADRNFSIST-ETP----SDLNDSRDDDD--
---------------EIG--ESIRMGL--------SRL-PRFIHEAASTKAEKFMLDRESDGTLYSYASSTIVFALLALYDKRH--PIIMNAVQGLTALQ
CRVDK-VTIQNS-SSTIWDTALISYALQESGVDG-DQQTTQRAAAYLLSRQQD--KTADWSINRDTVPGGWGFSETNTLNPDVDDTTAALRAIHSLS-HT
---TP--IYQHSTNRGLNWVLSMQNKDGGWPAFEKNTDKEM---LTAIDGAKSAAIDPSGADLTGRTLEYLGNFCGF----G--MKHDFIKRGTEWLITH
QEKNGSWYGRWGICYIYGTWAALTGLEAAGLPAD-HSAIQRGAAWLLEIQNPDGGWGESCTSDRVYMPLG--QSTASQTAWALDALIAVQAP---STAVN
RGINRLFELL-HEDDWTASYPMGGLPGSFYTHYHSYRYIWPLLTLSHYKKKYGVM--
>tr|A4IPI8|A4IPI8_GEOTN Squalene-hopene cyclase OS=Geobacillus thermodenitrificans (strain NG80-2) GN=GTNG_1884 PE=4 SV=1
---------------------------------------------------------------------------------------------MAGERSA
LITALKRSQAADGSWRFPFETGISTDAYMIILLRTLDINDE-P---LIQALVERIESRQEANGAWKLFADGDGNVTATVEAYYALLYSGYRPTDR---HM
QKAKRRILDMGGLDRVHLFTKVMLALTGQYPWPGRFPLPLEFFLLPPSFPLNMYDLSVYGRANMIPLLIAADSRYSRKT-DKP----SDLFASRG-----
---------------SLL--TYVK-----------RSL-PAQLHQAAKQRAVRYLFEHEPDGTLYSYFSSTFIFALLALYRNDD--PRIRQAVRGLRSLR
TTIDGHVHLQYT-TASVWNTALASYTLQEAGVPM-TDRAIEKANRYLLSRQNV--RYGDWAVNPYSTPGGWGFSDVNTMNPDVDDTTAALRAIRQAA-AK
---ET--AFRHAWDRANQWLFSMQNDDGGFAAFEKNVSSRF---WRPIEGAEFLLMDPSTADLTGRTLEYFGTFAGL----T--KDQRAVSRAVDWLLSH
QERNGSWYGRWGICYIYGTWAAITGLTAVGVPAH-HPALQKAVRWLLSIQNDDGGWGESCKSDGAYVPLG--DSTPVHTAWALDALVAAAEP---TLEMK
AGFRALFRLL-HHPDWTASYPVGGMAGAFYIHYHSYRYIFPLLALAHYEQKFGPL--
>tr|A0A0A5IAX7|A0A0A5IAX7_9BACI Squalene-hopene cyclase OS=Pontibacillus halophilus JSM 076056 = DSM 19796 GN=N781_14010 PE=4 SV=1
-------------------------------------------------------------------------------------------------MRL
LQDKAYEHQRTDGSFSFCFENSPMTDAWMVILLKSLGVKDD-S---FIASLTDRLLRLQHKEGYFELYKD-GRNLSATIEAYYALLLAQVVQSDE---RM
KRAEAFIVQHGGLEAASSLTKVMLAVTGQMEWPRVYHIPILFALLPPTAPLSFYDFGGYARVHMSPILILSDSRFKLIR-RGP----THLHKYRDTS---
---------------DFL--QAVHEGL--------KTL-PNELVKRARRTLETYMLQREPDGTLYSYFSSTFIYALLALYSKRD--PIIIKAIQGLKGLR
FETKLGIHIQNS-PSTVWDTSLLTYALHQSGITQ-TSSSLVKAVSYIARQQHT--RFGDWAKNQAATPGGFGFSPTNTINPDIDDTTAALRAIQPHL-TS
---SS--PLRSAWDRGLRFVLTMQNSDGGWPAFEKDTYKSI---LTPLDGAEAAAIDPSTADLTGRTLHFLGKDANL----T--LLQPNIQKAVEWLISH
QEKDGSWYGRWGICYTYGTWAALTGMKAVGVSHE-DDSVQRGLEWLERIQLPDGGWGESCRSDVEYIPLH--HSTISHTCWALEVLLAWNNM---TPAIE
KGIKRLIMLV-HEPDAWYSYPTGGLPGDFYIYYHSYNIIWPLLVLSEYRKKA-----
>tr|R9CFJ8|R9CFJ8_9BACI Squalene-hopene cyclase OS=Bacillus nealsonii AAU1 GN=A499_03188 PE=4 SV=1
---------------------------------------------------------------------------------------------VKTEQQR
RVKELVEHQQANGSFPFRFQGSLMTDAFYIITIRALDIQTE-E--ENIRLLTKTLRATQHREGYWKAYSDPNGHLSATIIAYTALLYSGHYKNDN---QM
KKAKAFIVKNGGLAKAHFMIKWMLSVNGLYPWSHMIYIPMTFLLLPTFQPINFYQFSAYARIHFIPMLIAANKKFTIDA-KTP----DDLFARDIAYPS-
---------------SPI--TFLWKEM--------KRI-PSYLHHLGFQYGEKYMLDREEDGTLYSYASATFIYALLALYKKDS--PVIQKAVTGLSSLI
DKRGEQSHLENS-TSTVWDTGLISYTLQQAGMAT-DTTPIRKATKYLLTKQHT--KKGDWQVNPHTEPGGWGFSDINTNNPDNDDTSAVLRAITAPA-AI
---DQ--TVHQAWQKGTNYLLSMQNRDGGWGAFEKNTDWEI---LKPIENAKDAAIDPSTADLTGRVLEYLGNFAHL----D--YTHPHIKRAKSWLIDH
QEKDGSWYGRWGVCYIYGTWAAITGLAAVGMDVN-HPTIKKAIAWLKKIQQSDGGWGESCQSCEKYVSLP--FSTESQTAWAVDALVAAGEA---SKEVK
RGISYILE---KQEDDAITYPTGGLPNQFYIYYHSYNKIFPLLALSHYKKYITNK--
>tr|K6CYI1|K6CYI1_9BACI Squalene-hopene cyclase OS=Bacillus bataviensis LMG 21833 GN=BABA_20891 PE=4 SV=1
---------------------------------------------------------------------------------------------VKAGIDW
IKEMLRKDQSPDGSWDYPFETGISTDAFMIILLRTLEINDE-E---LIEGLTKRILSRQEKNGAWKLFHDGAGNLTATVEAYYALLYSGYYKDDT---RL
WAAKKFILANGGLEEVGMYTKIMLALTGQYKWPAFSPLPIEVVLLPLHFPINFYSFSVFGRANLTPIMIVADKKFTMKT-SSP----SHLHLHRNDD---
---------------SLF--SFIEDGV--------TNL-PDQLHKLAIERAKKYMLDREPDGTFYSYYSSTFIFALLSLYDKTD--PIITKAIDGIKSMK
CEIDGYPHMQYT-TANLWNTALIGFGLQTAGIAP-EDPMVVQANRYLLERQHH--KFGDWVINPKTMPGGWGFSAVNTIVPDVDDTTAALRSISMIA-PS
----E----LQTWERAIAWTLSMQNDDGGWPAFERNVNSKL---LQPIEKAEFLLADPSCADLTGRTLEFFGQYTNL----S--TEHTATRRGIRWLLKN
QEKDGSWYGRWGICYLYGTWAAITGLLAVDVAAD-HSAIQKAVDWLRRIQNKDGGWGESCHSDSKYVPLK--ASTLTHTAWSLDALIAVSDP---TPEIE
KGINYLIGAL-KNDDWTTDYPKGGMAGGFYIHYHSYRYIFPLLALAHYREKFEL---
>tr|A0A0C2RLD5|A0A0C2RLD5_9BACL Strain SF-57 contig00008, whole genome shotgun sequence OS=Jeotgalibacillus campisalis GN=KR50_09220 PE=4 SV=1
---------------------------------------------------------------------------------------------INELIGQ
LINEIEAHQAPDGSFRFCFENSLMTDTNMMLLLKTFTT-DE-S---LMNELGARVASLQHPDGYWSIYPGN-GNLSATIEAYFALLYTGYWKSER---SA
QKASRFILAQGGLGAAHSMTKIMLAIHGQYPWPNLLHLPVHFILFPSSSPVSFYDFSSYARVHMAPILLLTDSRFQLGE-KDP----SALLIRTPS----
---------------SLL--SGIYQTA--------SSI-PHLVHQRARKRLVTYMLQREGDGTLYSYVSSTFLFALVSEYSKQH--PLIQKAITGLKTHR
CLTNNGWHIQNS-TSTVWDTALLCHALHDLPFSP---YKRKKAEVYLLKHQHD--KFGDWILADQTSPGGWGFSDSNTIHPDVDDTTASLRALSPSI-TV
---DP--SLKESYLRGVSWVLAIQNEDGGWPAFERAKTNQL---LTPMDGASHAAIDPSTADLTGRTLEFLSSEARL----P--FQHSAIQHAIRWLKKN
QQSDGSWYGKWGISFLYGTWSAVTGLSAAGLNGE-DPAIKKAVSFLERVQNEDGGWGESCLSDQVYIPLG--SSTPSQTAWALDALLSVHKK---TPSIE
RGINCLLGQL-KTKDWTYRYPTGGLPGNFYVYYHSYNYIWPLIVLKKYAAL------
>tr|A6CHM8|A6CHM8_9BACI Squalene-hopene cyclase OS=Bacillus sp. SG-1 GN=BSG1_02310 PE=4 SV=1
---------------------------------------------------------------------------------------------IDPEISR
LTQRLLEDQEEDGAWRYCFENSLMTDAYMIVLIRSLGIKKE-R---LVQELADRLLSQQEEKGFWKIYRDVEGNLSATVEAYFALLWSGAVEKDE---NM
VKARDCILSGGGLDKVHSMTKFMLAAHGQYPWDRFFPVPVEVILLPTYFPVSFTDFSAYARVHLAPLLLLKSERYIRKT-STP----SYLLKDQEDS---
---------------SFI--EYVTSGV--------EAI-PANLNDLAKKTALNYMLAREPDGSLYSYFSSSFIIALLSQYSRKD--PLVVNAIKALISYQ
CKGDGYPHIQNS-PSTIWDTALISHALQSSGVDS-RNAQILKASHYLYRHQHT--QKGDWASAPQTAPGGWGFSESNTINPDVDDTTAALRALKLDA-YT
---DP--VKRMAWNRGVKWALSMQNKDGGWPAFEKNKNKDI---LSPMDGAEDAALDRSCADLTGRTLEFLGNDAGM----G--RENSQVLKGIEWLMNN
QENDGSWYGKWGICYIYGTWAALTGMMAAGMSAD-HQSIIKAIKWLYQIQNSDGGWGESCRSDKEYISLG--ASTPSQTAWALDALISINDP---TKEID
RGIESLVRLL-NTDDWRKEYPTGGLPGRFYIHYHSYPYIWPLLALSNYKTKFLEV--
>tr|A0A098F1L0|A0A098F1L0_9BACI Squalene--hopene cyclase OS=Bacillus sp. B-jedd GN=BN1002_03461 PE=4 SV=1
---------------------------------------------------------------------------------------------VKDGIGK
LIKQLKQSQSPRGSWDFPFETGITTDCYMIILLRTLEIDDE-K---LIRGLVERILSRQEKNGAWKLFFDGEGNLTATIEAYYALLFSGFIKSDG---RL
RAARSFIQQHGGIEKAHMFTKIMLALTGQINWPRFFPFPLEIILLPVSFPLNFYSFSEFGRSNLAPIMILAHRRFQLRT-AGP----AGDLQGREAGID-
---------------GLD--SFFAKNF--------KKL-PAELHQLATEKTKNYMLEREPDGTFYGYFSSTFIFALLSLYKNSD--PVIVTAVAGLKGMK
CEIGGFPHMQYT-TAAVWNTALISYALQEAGVKS-ADPAVEKANRYLLKKQQY--KYGDWAINPSAFPGGWGFADSNTVHPDVDDTTAALRAIAAKV-GE
---NP--DYRHAWDRGTQWVLSMQNKDGGWPAFEKNTDSRL---ISPIQKPTFLLADPSSADLTGRTLEFLCNETNL----E--RNHSSVKSGVEWILNN
QEKDGSWYGRWGICYIYGTWAAVTGLRAAGVLPS-HPAIKRAAEWLKSIQNSDGGWGESCRSDSAYVPLG--ASTLTDTAWATDALIAATGP---TTEIK
VGITYLLQHL-DTINWTTTYPKGGMAGDFYIHYHSYNLIFPLITLAHYQRRE-----
>tr|A0A0B0D5Y2|A0A0B0D5Y2_9BACI Squalene-hopene cyclase OS=Halobacillus sp. BBL2006 GN=LD39_05900 PE=4 SV=1
---------------------------------------------------------------------------------------------IESEINR
LIQLLNKEQSRDGSWNYAFETGIITDAYMIILLRLLEIHDE-E---LIDQLVGRIISKQQENGAWKLFYDESGNLSSTIEAYTALLFSGKYKSDP---EL
VKARTFIVERGGVKNSELFTKILLCLIGQYPWPKKNPIPIEVILLPPSFPVNIFDISVFGRANIIPILLLAHKKYQSIS-IYP----SDIGGGKGREDD-
---------------NYF--TYLIDEI--------KSK-LFHFESEAIAQAKNYMLTREPDGTMLSYFSSTFVMALRSVYKKDH--AVILKAIEGLKSIA
CKIDGYTHMQYT-TADVWNTALISDALQKSGVPA-DNSVIKQANSYLLSRQQY--KFADWMINPETLPGGWGFSDINTLNPDVDDTTASLRALRSMF-ST
---QT--DAIQAWNRGVQWTLSMQNPDGGWPAFERRIDKEY---LTPLQKAEFILTDASSADLTGRTLEFLGNYTNM----D--SHSPPIVKAKKWLKNN
QRKDGSWYGRWGICYLYGTWAALTGLMACEEKKS-SPAVQRSVKWLSEIQNRDGGWGESCNSDIEYVPLG--SSTLTHTSWALDALIAVIDP---SPAID
RGIQYLITNG-EKNEWTEDYPKGGMGGAFYVHYHSYRFIWPLMTLAHYQNKFL----
>tr|A0A024P564|A0A024P564_9BACI Sporulenol synthase OS=Halobacillus karajensis GN=sqhC PE=4 SV=1
---------------------------------------------------------------------------------------------VLSEMER
LINLLKRDQSQDGSWDYAFETGVATDSYMIILLRSLEIHEE-K---LIQALSERIVSKQEKNGAWKLFYDGPGNLSATIEAYYGLLYSGYASEDP---NM
KKAEQFILQHGGLNEAGMFTKIMLALTGQQAWPKFFPIPLEAILLPVHFPLNLYDISVFGRANMVPLLLLAHEKYQLTT-PQP----SHLYVHFDESGH-
---------------NYL--SSLTKAL--------QSS-LNHLEEIAAEQAKQYMLKRESDGTFLNYFSATFIFAFMSQFSKKD--KKIRNAVNGLKSMA
TLIDGRVHMQYT-TADVWNTSLISYTLQEAGVSE-KDDVIQKANRYLLSRQQF--KYGDWVVNPSTSPGGWGFSDLNTINPDVDDTTASLRAIQKIL-SY
---QP--GFHQAWERGTQWGMSMQNTDGGWPSFERNVDKKI---LNPVQGGEFLLLDPSTADLTGRTLEFLGNFTNV----N--KNHSAIARGIEWLRKK
QNQNGSWYGRWGICYIYGTWAAVTGLIACGADSK-APMLRKAVQWLKDIQNEDGGWGESCKSDTEYMPLK--ASTLTHTAWALDALISASSP---TPAIE
KGIQFLIEKG-NNKNWTHNYPKGGMGGAFYIHYHSYRYIYPLLALSHYKHKFQRE--
>tr|A0A0C2Y1Q7|A0A0C2Y1Q7_BACBA Strain MTCC 1458 Contig21, whole genome shotgun sequence OS=Bacillus badius GN=SD77_2726 PE=4 SV=1
---------------------------------------------------------------------------------------------VNDLMAQ
ITEQLKRSQTADGSWAYPFETGISTDAYMIILLRTLGINDE-E---LIRGLAERILSRQATNGAWKLFQDKDGNVTATAEAYYALLYSGYVKGDA---RL
QAAKTFIRAKGGIENTHMLAKIMFALTGQYRWPPCFPIPIEAVLLPFSFPVNLYDLSVFGRANLIPILVVATKKYKKKT-KKP----SDLFISRSDS---
---------------KLR--AAMENEI--------RHL-PHSIHSAAVQRAKQYMLDHEPDGTLYSYFSSTFIFALLSLYAKSD--PVILEAVAGLKSMK
CTIGGHPHIQYT-TASVWNTALISYALQEAEVSP-SDPVIQTANRYLLRRQQY--KYGDWVFNSNAFPGGWGFSNINTMNPDVDDTTAALRSLASLV-NS
---SS--TVYQSWKRGVGWTMSMQNTDGGWPAFEKNINKKL---FNPIEGARFLLTDPSSADLTGRTLEFFGSYTNV----Q--KKHSLLKKGTDWLIEN
QETDGSWYGRWGICYIYGTWAAMTGLKVAGTGTQ-TPVIQRAVHWLCRIQNEDGGWGESCTSDIKYIPLG--SSTLIHTSWALDALIAAADP---TKEIR
AGLSYLLRSF-HKNDWTIDYPAGGMAGGFYIHYHSYRYIFPLLALAHYKRKFG----
>tr|Q2B3H0|Q2B3H0_9BACI SqhC OS=Bacillus sp. NRRL B-14911 GN=B14911_17720 PE=4 SV=1
---------------------------------------------------------------------------------------------VKSEIER
LKQQLLSEQTPDGSWNHPFDTGCMTDIYMIVLLRTLEEEDE-E--ELIKELAKGILSRQGKDGAWRLFHDHEGSLSLTIEAYYALLYSGYYKNHP---AL
VKARRVITKGGGLKKAGMYTKIMLALTGQYPWPLLFPVPMEVILLPRSFPLNMYDISVFGRSNLIPVILLGNKKFSRKT-ALP----GDLSVRDDDP---
---------------SLT--SFLAAGV--------KAL-PRQIRAWSIEKAREYMQSHEPDGTLYNYFSSTFIFALLALGGPEE--PAIRNAVAGLKRMT
VKADGRTHIQYT-TAAVWNTALISHALQEAGVPP-KENAIQKANQYLAGQQHR--RFGDWIVNTKAEPGGWGFSRFNTINPDVDDTTAALRSLYQPA-RE
---KP--HYDDIWKKGLLWTLSMQNRDGGWPAFERNVDKKL---LHPIQGAEFILTDPSTADLTGRTLEFLGKAGYA----D--ASLPPIKKAVKWLKKH
QEPNGSWYGRWGICYIYGTWAAVTGMAAVGVTLE-DKSMKKGIDWLLSIQNEDGGWGESCRSDMEYIPLK--ESTLTQTAWAVDALAAAGMD---STPSR
KGAAFLVREG-KRKDWTADYPMGGMANFFYIHYHSYRCIWPLLALSHYIEKSEAP--
>tr|T0DCL2|T0DCL2_9BACL Uncharacterized protein OS=Alicyclobacillus acidoterrestris ATCC 49025 GN=N007_04345 PE=4 SV=1
---------------------------------------------------------------------------------------------VRQAVDK
LVRRLENDQAMDGSWRYCCESGPMTDAYMILLLRALGLADN-D---VIQPLSSRILSLQNHHGAWSLFHDPGGNLSATVESYYALLSAGHDTDDE---PL
EQARHFIRQHGGLAQIGTSTRAMLACTGQLPWKHY-KVPLIWTLLPKWFPVNFFDFVGYARGHIAPVLIAAHCGTPATS-PYP----SASLLQPTREN--
-----------------------THKQ--------AQL-PLSVKTWSLQRLEHFVLKHEQDGTLMSYASATFIYALLGMYPKHH--PTIVQAIEGLKSFI
YPLSNGAHLQNM-TSTVWDTALLSYAIQTIPQID-TTTMVRKAQTYLLVRQHH--QTRDIEPDARSDGGGWGFSDVNTLIPDVDDTTAALRAITHSA-KT
---SS--SVQCAWRRGLNWVLSMQNSDGGWPAFERNKNKRI---VSAIDGAKATLTDPSCPDLTGRTLEFLCNDAGY----T--QKDKVVQRAVNWLLKH
QEVDGSWYGRWGICFIYGTWAALTGLLAAGLDAS-HPSIRRAVAWLHDIQNADGGWGESCLSDTRYVPLG--RSTLSQTAWATDALITASST---MPAIE
HGIRFLSTGK-DQSDWTTSYPTGELPGGFYIHFHSYNTIWPLLTFGHYLQKFQTA--
>tr|A0A0D7XIF4|A0A0D7XIF4_BACAM Squalene-hopene cyclase OS=Bacillus amyloliquefaciens GN=UZ38_24525 PE=4 SV=1
---------------------------------------------------------------------------------------------VKAFRQK
TLAKLQNRQRPDGSWRFCFEGPVMTDSFFILMLTSLG-QDS-S---LITSLAERIRSKQSGDGAFRNHPDTAGNLTATVQGYTGMLASGLYRRDA---HM
QKAEAFIKATGGLKNVHFMTKWMLAANGLYPWPRAY-IPLSFLLIPPYFPLHFYHFSTYARIHFVPMAITFNRRFSLKN-NQG----RHLDEAMSKPLE-
---------------TFY--SFNLQ-W--------KQL-PAYVHQLGFEAGKKYMLDREEDGTLYSYASATMIYSLLAMISKNA--PVVKKAVGGIKSLI
SSCGEGFHLENS-TSTVWDTALISFAMQESGIPE-QHSSISSAADYLLKRQHV--KKADWAVNPQAAPGGWGFSHINTNNPDLDDTAAALKAIPYQR---
--------RPAAWNRGLTWLISMQNKDGGFSAFEKNVDHPL---IRPLESAADAAVDPSTADLTGRILHLLGLKERL----T--DDHPAVRRALRWLDHH
QEADGSWYGRWGVCFIYGTWAALTGMKAVGISHN-HSSVRKAVSWLKSIQLEDGSWGESCKSWEAFVPLH--FGTVVQSSWALEALLQYERD---DPKIL
KGIRFLTDDH-ESSPERLEYPTGGLPKQFYIRYHSYPFVFSLLASSAFIKKAEMR--
>tr|A7GQS3|A7GQS3_BACCN Squalene/oxidosqualene cyclase OS=Bacillus cereus subsp. cytotoxis (strain NVH 391-98) GN=Bcer98_2232 PE=4 SV=1
---------------------------------------------------------------------------------------------VCAEIER
TITALHTMQQQDGAWRFCFEGSPLTDCHMIFLLRLLEK----E---EIEPFVARLTSIQTNEGTWKLYED-RGNVSTTIQAYAALLASGMYKEDV---NM
KRAEAFIQERGGIARSHFMTKFLLALHGGYEYPRMFYFPTPILFLPEDSPLSIFELSSSARIHLIPMMICMNKRFVSKI-LP-----DHISGSSKS--W-
----------F----SLF--ETILGEVK-------VT--PLSLHHKGDKEAERFMIERDRNGTLYSYASATFIYALLALHHIQS--PLIQQAVAGLRTYK
WHME-GIHLQNS-PSTVWDTALLSYALQEANVNE-STPMIQTATEYIWQRQHH--EKKDWSLAPTLSPGGWGFSDVNTTIPDVDDTTAALRALARSRKR-
----N-RRIEEAWKKGVNWVKGLQNKDGGWAAFEKGVTNRF---LTPLENSGDMMTDPSTADITGRVLEFFGTYAPN----E--LQDHQKNRAITWLMDV
QENNGSWYGKWGVSYIYGTWAALTGLRAVGVANT-HPALKKAVMWLERIQHRDGGWGESCRSSIEFVPLS--FSTPSQTAWAIDALISYYD--E-TPVIR
KGISYLLEHAAS----HQEYPTGGLPNGFYIRYHSYSYMYPLLTFAHYINKYRK---
>tr|I0IJN8|I0IJN8_BACIU Tetraprenyl-beta-curcumene cyclase OS=Bacillus subtilis GN=tc PE=4 SV=1
---------------------------------------------------------------------------------------------VRRYQKK
TIAELKNRQNADGSWTFCFEGPIMTNSFFILLLTSLDENEK-E---LISALAAGIREKQQPDGTFINYPDTSGNITATVQGYVGMLASGCFRSDP---HM
RKAEQSIISHGGLRHVHFMTKWMLAVNGLYPWPVLY-LPLSLMALPPTLPVHFYQFSAYARIHFAPMAVTLNQRFVLKN-RNP----RHLDPHMTKPFT-
---------------DLT--SIWSH-W--------NRI-PFAFQQLGLQTAKTYMLDREKDGTLYSYASATIVYSLLSLVSRYS--PVIKRAINGIKSLM
TKCNI-PYLENS-TSTVWDTALISYALQKNGVTE-TDGSITKAAAYLLERQHT--KRADWSVNPSAAPGGWGFSNINTNNPDCDDTAAVLKAIPHSY---
--------SPSAWERGVSWLLSMQNNDGGFSAFEKNVNHPL---IRPLESAEDAAVDPSTADLTGRVLHFLGEKAGF----T--EKHQHIQRAVNWLFEH
QEQNGSWYGRWGVCYIYGTWAALTGMHACEVDRK-HPAIQKALRWLKSIQHDDGSWGESCNSAEVYVPLH--KGTIVQTAWALDALLTYESE---HPSVV
KGMQYLTDSS-YHGADSLAYPAGGLPKQFYIRYHSYPYVFSLLAVGKYLNSIEKE--
>tr|A0A0B6AKW3|A0A0B6AKW3_BACME Squalene/oxidosqualene cyclases family protein OS=Bacillus megaterium NBRC 15308 = ATCC 14581 GN=BG04_4486 PE=4 SV=1
---------------------------------------------------------------------------------------------VQLEIQR
RIAYLRPTQKNDGSFRYCFETGVMPDAFLIMLLRTFDLDKE-V---LIKQLTERIVSLQNEDGLWTLFDDE-HNLSATIQAYTALLYSGYYKNDR---IL
RKAERYIIDSGGISRAHFLTRWMLSVNGLYEWPKLFYLPLSLLLVPTYVPLNFYELSTYARIHFVPMMVAGNKKFSLTS-RHP----SHLDVREQKESE-
---------------RAS--IFLVDHL--------KQL-PSYIHKLGYQAAERYMLEREKDGTLYSYATSTFIYGLLALYKKDS--FVIQKAIDGICSLL
STCSGHVHVENS-TSTVWDTALLSYALQEAGVPQ-QDPMIKGTTRYLKKRQHT--KLGDWQFNPNTAPGGWGFSDINTNNPDLDDTSAAIRALSRRA-QT
---DT--DYLESWQRGINWLLSMQNKDGGFAAFEKNTDSIL---FTPLENAKDAATDPATADLTGRVLECLGNFAGM----N--KSHPSIKAAVKWLFDH
QLDNGSWYGRWGVCYIYGTWAAITGLRAVGVSAS-DPRIIKAINWLKSIQQEDGGFGESCYSASLYVPLS--FSTPSQTAWALDALMTICPK---DQSVE
KGIKFLLN---NLTEQQTHYPTGGLPGQFYIQYHSYNDIFPLLALAHYAKKHSS---
>tr|E1UV98|E1UV98_BACAS SqhC protein OS=Bacillus amyloliquefaciens (strain ATCC 23350 / DSM 7 / BCRC 11601 / NBRC 15535 / NRRL B-14393) GN=sqhC PE=4 SV
---------------------------------------------------------------------------------------------VRSRQRK
TISLLREKQNADGSWSFCFEGPILTNAFLILLLTSLG-NDK-E---LIAELAEGIRAKQRPDGTFANYPDRKGNVTATVQGYVGLLASGLYRSEA---HM
IQAERFIISNGGLRNVHFMTKWMLAANGLYPWPALH-LPLSFLVIPPSFPLHFYQFSTYARIHFVPMAVTLNKRFSLKN-PNP----EHLDQHMTKPFT-
---------------DLA--SLFAH-W--------KRL-PAAFHQLGLRTAKTYMLDREEDGTLYSYASATIVYSLLALVSRHS--PVIRKALAGTKALL
TSCGI-PYLENS-TSTVWDTALLNYALMESGISD-NDQMITSAARFLRERQQT--KVADWAVNPHAEPGGWGFSNINTNNPDCDDTAAVLKAIPRKL---
--------YPASWERGLSWLLSMQNSDGGFSAFEKNVNHPL---IRPLESAEEAAIDPSTSDLTGRVLHCLGK-AGL----S--SDHPQVEKAVQWLIRH
QEEDGSWYGRWGVCYIYGTWAALTGMKACGVSHN-HPAVKKAIRWLKSIQNEDGSWGESCKSAEIYVPLS--YGTVIQTAWAAEALLQYEKH---HQAVT
KGISFLIENR-HYEGAHFTYPTGGLPKQFYIKYHSYPYVFSLLALSTFMKVSEKE--
>tr|A0A0D7FP82|A0A0D7FP82_9BACI Squalene-hopene cyclase OS=Bacillus safensis GN=UM92_06985 PE=4 SV=1
---------------------------------------------------------------------------------------------VNEFIEE
LHMQMQRRQREDGAFVFCFEGPMMTNAFLIMLLKAVG-SDQ-A---LVHQLAEAIREKQNEDGSFSLYHD-TGHVTATVQGYCGMLVSGRFQDEP---HM
EKAAQYIRSKGGLKNVHFMTKWMLAVNGMHPWPYFY-APLSFLLIPTYFPLHFYHLSAYARIHFVPMMIALNKRYTS-H-EKP----AHLDANMTKPFD-
---------------STH--HFLTY-M--------RSY-DSRLDFFGYEAAKRYMFDREKDGTLYSYLSASIVYALMSLYSPGH--HLILKAVKGMKKLV
TVCQR-MYAENS-TSTVWDTALVSYASQKAGKKQ-EDPVITKSFLYLLNRQQM--KKADWAINRHAAPGGFGFSDINTNNPDCDDTQIVLKAIPKTY---
--------APVQWKRGFHWLLSMQNRDGGFSAFEKNQDHFL---LRPLESAEDAAIDPSTPDITGRVLHLIGLEQKN---MS-PPIQRQKDQCVKWLLDH
QEKNGSWFGRWGVCYIYGTWAALTGLKAAGIPST-HPAVQKACRFLKQIQREDGSFGESCKSAEIYVPLP--FGTVVQTAWAAEALLQYEKD---DKTIL
KAISFLIHH--QHTSEAVHYPVGGLPKQFYITYHSYPFVFPMMACSTFLEEMRRK--
>tr|C2X1A9|C2X1A9_BACCE Squalene-hopene cyclase OS=Bacillus cereus Rock4-18 GN=bcere0024_32620 PE=4 SV=1
---------------------------------------------------------------------------------------------VHEEIAR
RTTALQTMQRQDGTWRFCFEGAPLTDCHMIFLLKLLGR----K---EVEPFVKRLASLQTNEGTWKLYDD-MGNLSATIQSYAALLASKKYKEDA---NM
KRAEMFITERGGVARAHFMTKFLLAIHGEYEYPSLFHLPTPIMFLQNDSPLSIFELSSSARIHLIPMMLCLNKRFVGKL-LP-----NHIAGGG-G--W-
----------F----PMF--QTLLGNVK-------IS--PLSLHHKGNEEVERFMKERDENGTLYSYASASFIYALLALHSIQS--PMIQKAITGITSYI
WKME-GNHLQNS-PSTVWDTALLSYALQEARVSK-ESKMIQNASAYLLKKQHK--KKADWSVAPVLIPGGWGFSDVNTTVPDVDDTTAVLRALAQSR-G-
----N-GNVDDAWKKGTNWIKGLQNNDGGWGAFEKGVTSKL---LAPIENASDMITDPSTPDITGRVLEFFGTYTQN----E--LPEKQKQSAINWLMNE
QEENGSWYGKWGICYIYGTWAVMTGLRALGITSA-HPSLKRATLWLEHIQHEDGGWGESCQSSVEFATLP--FSTPSQTAWALDALISYYD--E-TPAIR
KGISYLLANPYV----NEKYPTGALPGGFYIHYHSYAHIYPLLTLAHYAKKYKK---
>tr|C3C5H6|C3C5H6_BACTU Squalene-hopene cyclase OS=Bacillus thuringiensis serovar tochigiensis BGSC 4Y1 GN=bthur0001_33190 PE=4 SV=1
---------------------------------------------------------------------------------------------AHEEIAR
RATALQTMQREDGTWRFCFEGAPLTDCHMIFLLKLLGR----K---EIEPFVKRLATLQTNEGTWKLYED-VGNLSATIQSYAALLASGKYKEDA---NM
KRAENFIKERGGVARAHFMTKFLLAIHGEYEYPSLFHVPTPIMFLQNDSPLSIFELSSSARIHLIPMMLCLNKRFVGKL-LP-----NHIAGGG-G--W-
----------F----PLF--QTLLSDVK-------IS--PLSLHHKGYEEVERFMKERDENGTLYSYATASFIYALLALHSLQS--SMIQKAIAGITSYI
WKME-GNHVQNS-PSTVWDTALLSYALQEAHVPK-DNKMLQNATAYLLKKQHT--KKADWSVAPALTPGGWGFSDVNTTVPDVDDTTAVLRVLARSK-G-
----N-EKLDHAWQKGINWVKGLQNNDGGWGAFEKGVTSRI---LAPIENASDMITDPSTPDITGRVLEFFGTYAQN----E--LPEKQKQSAINWLMNA
QEENGSWYGKWGICYIYGTWAVMTGLRSFGIPSS-NPSLKRAALWLEHIQHKDGGWGESCHSSVEFVTLP--FSTPSQTAWALDALISYYD--E-TPVIR
KGISYLLANPYV----NEKYPTGGLPGGFYIRYHSYAHIYPLLTLTHYIKNIENK--
>tr|A0A084GST9|A0A084GST9_9BACI Squalene-hopene cyclase OS=Bacillus indicus LMG 22858 GN=AZ46_0206860 PE=4 SV=1
---------------------------------------------------------------------------------------------TEDAVQK
RISELRGVQRPDGSFRFCFEGGPMTDAFMIITLRSLGNQDE-Q---LIEKLVRRLLRIQSDDGMWRLYEDQDGNLTATVQAYTALIISGHFAASP---QL
QRAEAFILANGGLSDVHFMTKWMLAVNGLYPWPKHFRFPLSYLLLPASSPLSMYQLSSYARIHFMPMILAMNKKYIHKG-LGA----SHLYASKPKIDW-
---------------SGP--NLFLQTI--------RSL-PAYLHKSGYQAAERYILDREADGTLFSYASATFIYGLLALYSEQS--SQIQRALSGLKSLI
YKKDDLATLENS-TSTLWDTALLNYSLQSAGLSC-HDPIIAAASAYLLKRQHI--KKADWAVNPSKEAGGWGFSDINTNHPDNDDTAAALRALTPAA-MY
---DP--LIFSSWNRGTSWLLSMQNRDGGFAAFEKNTDSAL---AAPLENAGDAAADPSTADLTGRVLEYFGSFAGL----K--KYHPSAKAAINWLKSN
QEENGSWYGRWGVCYIYGTWAAITGMRAAGVSPN-NASIQNAVNWLLSIQNRDGGFGESCRSCEVYVPLG--YSTPSQTAWALDALLTVLDE---HEAVQ
LAVNRLLQ---F-DQKCDEYPTGGLPKQFYIRYHSYGRIFPLLALSRYLKMK-----
>tr|A0A084H0Z9|A0A084H0Z9_9BACI Squalene-hopene cyclase OS=Bacillus cibi GN=GS18_0206555 PE=4 SV=1
---------------------------------------------------------------------------------------------TEDAVRK
RIAELRDVQRTDGSFRFCFEGGPMTDAFMIITLRSLGDQDE-Q---LIEKLVRRLIKIQSHDGVWRLYEDKAGNLTATVQAYTALVISGHFAASP---EL
QRAETFILANGGLSDVHFMTKWMLAVNGLYPWPKRFRFPLSYLLLPASSPFSMYQLSSYARIHFMPMILAMNKKYIHKG-LEA----SHLYASKPKIDW-
---------------SRP--NLFLQMI--------RSN-PAYLNKSGYQAAEKYILDREADGTLFSYASATFIYGLLATYKEQS--SQIQRAISGLKSLI
YEKDGLATLENS-TSTLWDTALLSYSLQASGVSC-RDPMIAATNGYLLKRQHA--KKADWAVNSKSEAGGWGFSDINTNHPDNDDTAAALRALTPAA-VY
---DP--IMFSSWNRGTSWLLSMQNRDGGFAAFEKNTDSAL---AAPLENAGDAAADPSTADLTGRVLEYLGSFAGL----K--KNHPSAKAAINWIKSH
QEKDGSWYGRWGVCYIYGTWAAITGMRAAGVSTN-NASIQKAVTWLLSIQNEDGGFGESCRSCEVYVSLG--YSTPSQTAWALDALLTVLDE---HEAVH
LAVNRLLL---F-DQKSEEYPTGGLPKQFYIRYHSYGRIFPLLALSRYLKMN-----
>tr|M5PHV6|M5PHV6_9BACI Squalene-hopene cyclase OS=Bacillus sonorensis L12 GN=BSONL12_01067 PE=4 SV=1
---------------------------------------------------------------------------------------------AKAFRQK
TLKDLQNRQETDGSWRFCFEGPVMTNSFLILLLTSLG-HDS-S---LISSLARRIRSEQNEDGTFRNYPDAEGHLTATVQGYTGMLASGIYRDEP---HM
QKAEAFIRSKGGLRSVHFMTKWMLAANGLYPWPRLY-LPLSFLLIPPVFPLHFYHFSAYARIHFVPMAIALNKKYVLKN-EQG----RHLDENMSKPLD-
---------------NFY--PFNLQ-W--------KEL-PVYVHNLGFEAGKRYMLDREQDGTLYSYASATIVYSLLSLISKND--PVIRKAVSGVKGLV
APCGEGLYVENS-TSTVWDTALLSYAMQEAGMSQ-KSPTVSSAADYLEKRQHI--RKADWAVNPHAKPGGWGFSNLNTNNPDVDDTAAALKAIPLNR---
--------RPADWTRGLAWLLSMQNKDGGFAAFEKNVDHPL---IRPIESADEAAVDPSTADLTGRALHALGLKAGY----T--ENHSAVRRALHWLYRR
QEKNGSWYGRWGVCYIYGTWAALTGMKAVGVSGE-HPSVKKALSWLKSIQLPDGSWGESCKSCEIFAPLA--YGTAVQTAWALEALLQYEDR---EPLIQ
KGFRFLIDDG-LHQPKHLVYPTGGLPKQFYIYYHSYPFVFPLLALSAFIKQMEMR--
>tr|A0A075LKD1|A0A075LKD1_9BACI Squalene-hopene cyclase OS=Terribacillus aidingensis GN=GZ22_07850 PE=4 SV=1
---------------------------------------------------------------------------------------------VKTAIEK
RISKLEELQQKDGSWRMCFEGAILTDCFYIITFTSFGKEAD-----TVEKLKLQLFKKQRDDGSWSAYPGRNGNLSATVLAYAALRFSGVS---K---DL
RTAERYISTNGGINKAHFMIRFMLAVHGMIPWPHFLKFPMTALLVPTTFPINFFQFSSYARIHFVPMLLLLNKKFKRLS-VNV----EHLLYEE----E-
---------------SPF--RTITNEW--------SRL-PARLHRAGYRYAEQYMKERESDGTLYSYASATFIYAYLALYEENN--PKIQQALKGIHGLV
NENCNGIHVENS-TSTVWDTALLSYALQQAGAPV-KQNMIQSANHYLLQRQHV--QKADWQIQSSVEPGGWGFSDSNTNHPDNDDTAAALRALTRQA-RQ
---DL--TVKRSWKKGSDYLLAMQNKDGGWAAFEKDTDWWV---LGPIENAEDAAIDPSTADLTGRVMEFLGTYASL----K--KDHSSMKKAVRWLYKH
QQLNGSWYGRWGVCYLYGTWAALTGLAAVGVNPT-EKHVKRAVNWLKAVQHEDGGWGESCRSAEVYVDLP--ISTVVQTAWAIDALIACGED---SKEVQ
QGISFLLS---PLLQASIDYPTGGLPGQFYIRYESYSHIFPLLTLSHYRIKAKS---
>tr|A0A080US30|A0A080US30_BACIU Squalene/oxidosqualene cyclases family protein OS=Bacillus subtilis subsp. niger GN=DK44_2078 PE=4 SV=1
---------------------------------------------------------------------------------------------VARCQKK
TITQLKNMQNADGSWSFCFEGPIMTNSFFILLLTSFEEN-E-E---LIIKLAKGIREKQRPDGTFTNYPGEKGNVTATVQGYVGMLASGCYRSDP---HM
IQAERFIISQGGLKDVHFMTKWMLAANGLYPWPALY-LPLCLLAIPPTFPLHFYQFSTYARIHFVPMAVTLNQRFFLKN-PNP----KYLDSHMSKPFT-
---------------DLS--SILAY-W--------KQL-PFSLHQLGFRTAKTYMLDREKDGTLYSYASATIIYSLLSLMSRHS--SIIQQALNGVKTLV
TECDI-PYLENS-TSAVWDTALISYSLQQSGVPE-KDLMITGAADFLLENQHK--KKADWSVNPHAAPGGWGFSKINTNNPDCDDTAAALQAIPRSL---
--------SPMSWDRGLNWLLSMQNKDGGFSAFERNVNHPL---IRPLESAEDAAVDPSTPDLTGRVLRFLGEKAGM----T--QDNRQIKKAVNWLIDN
QEDNGSWYGRWGVCYIYGTWAAITGMRACGTEAF-HPAVKKAVHWLKTIQHDDGGWGESCRSAEVYVPLR--YGTVTQTAWALDALLQYEED---HPSIT
KGLEFLINSE-NHNKQSLAYPTGGLPKQFYIRYHSYPLAFSLLAYSSYMKSIEKR--
>tr|A0A073JWZ7|A0A073JWZ7_9BACI Squalene-hopene cyclase OS=Bacillus manliponensis GN=BAMA_03265 PE=4 SV=1
---------------------------------------------------------------------------------------------VKHEVER
RITALRTMQRSDGTWRFCFEGSPLTDCWMILLLRLLQR----D---EIEPFVERLVSMQTNHGTWKLYED-PGHLSTTIDIYTALLASNYYKEDY---NM
KRAEAFISHEGGIANAHFMTKFMLAVHGQYKYPSLFYLPTPILFLPDESPLSIYQISSSARIHLIPMALCMNKRFVQRI-LP-----NYIIGKSNG--W-
----------F----SLL--ETMVAGVK-------VQ--PLSLHHKGYKAAERFMMEREQNGLLYSYASSTFIYALLALHSTQS--PVIISALRGLQSYV
WNTK-GAHVQNS-PSTIWDTALFSYALQEAGVAP-EDPLIQGANEYLIRKQHS--RYGDWHIAPTLSPGGWGFSDVNTTIPDCDDTTAVLRSLTEMAKK-
----D-RKGKQAWDKGIDWVTGLQNKDGGWGAFEKGVTSHL---FEPLENAKDMMTDPSTADITGRVLEFFGTYAPN----K--LLDENRNRAIRWLIEN
QENNGSWYGKWGVCYIYGTWAAITGLRAVHVSPE-HPGLQKAIQWLEAIQNRDGGWGESCRSSKEYIALP--FSTPSQTAWALDALISFYD--E-TPSIQ
KGIHYLIEHSLQ----HREYPTGGLPGSFYIHYHSYHRLFPLLTFAHYIKKYKK---
>tr|C3ANI1|C3ANI1_BACMY Squalene-hopene cyclase OS=Bacillus mycoides Rock1-4 GN=bmyco0002_27260 PE=4 SV=1
---------------------------------------------------------------------------------------------VRQEVER
KVTALRTTQYQDGAWRFCFEGSPLTDCHMIFLLRLLGQ----G---EMEPFVTRVASLQTNEGTWKLYED-SGNLSTTINAYVALLASGRYKEDI---NM
KRAEAFIRRQGGITKAHFMTKFLLALHGGYEYPSLFHFPTPMLFLPEDSPLSIFELSSSARIHLIPMMICMNKRFVSKI-FP-----DYISGGSKK--W-
----------F----PLF--QTLLGDVK-------LS--PLSLQHKGYKEAERFMIERETNGTLYSYASATFIYALLALHSIQS--PLISNAVLGLKSYI
WNMN-GTHLQNS-PSTVWDTALLSYSLQEAGVPN-DNQMIQKATDYLLQKQHK--EKKDWSVAPSLDAGGWGFSDVNTTIPDIDDTTAALRAIARSREG-
----N-QRIEEDWRKGIEWVKGLQNIDGGWAAFERGVTSHF---LTPLDNAGDMTTDPSTSDITGRVLEFFGTYAPH----Q--LKDDQKDRAIKWLMQA
QEKNGSWYGKWGVCYIYGTWAVLTGLRAVGVPSN-HTALQKAATWLERIQHNDGGWGESCRSSIEFISLP--FSTPSQTAWALDALITFYD--E-TPVIR
KGISYLLAHLNQ----NQDYPTGGLPDGFYIRYHSYHHIFPILTFAHYIKKYMK---
>tr|A0A090YTG1|A0A090YTG1_BACMY Squalene/oxidosqualene cyclases family protein OS=Bacillus mycoides GN=DJ93_435 PE=4 SV=1
---------------------------------------------------------------------------------------------VREEVNR
KITALRTMQKQDGTWQFCFEGALLTDCHMIFLLKLLGK----Q---EIEPFVTRLVSLQTNEGTWKLYED-PGNLSATIQAYTALLASGQFREDV---NM
RRAEAFIREHGGIARAHFMTKFLLAVHGAYDYPSLFHFPTPILFLQEDSPLSIFELSSSARIHLIPMMVCVNKRFVPQL-LP-----QHITGGG-G--W-
----------F----PVF--QTLLYDVK-------LS--PLSLHHKGYEEVERFMNERDENGTLYSYASATFIYALLALHPIQS--QVIQNAVTGLESYI
WNME-GSHLQNS-PSTVWDTALLSYALQEAGVFK-EDPMIQKATEYLLKKQQS--KKMDWSVAPSIQAGGWGFSDINTTIPDVDDTTAALRALAPSRDG-
----N-PKVEEAWEKGIKWVKGLQNMDGGWGAFERGVTSRL---LAPIENAGDMLTDPSTPDITGRVLEFLGTYAPN----E--LSDEQKECAIKWLLHE
QERNGSWYGKWGICYIYGTWAALTGLKAVGVSST-HPSVKKAILWLENIQHRDGGWGESGQSSIEFASLS--FSTPSQTAWALDALISYYD--E-TPAIR
KGISYLFANSTK----NEEYPTGALPGVFYINYHSYAKLYPLLTLAHYMKKYRK---
>tr|C2WAB2|C2WAB2_BACCE Squalene-hopene cyclase OS=Bacillus cereus Rock3-44 GN=bcere0022_27430 PE=4 SV=1
---------------------------------------------------------------------------------------------VHEEVKE
KMAALQAMQQQDGTWRFCFEGSPLTDCYMIFLLTLLGQ----Q---EIEPFVARLAALQTNEGTWKLYED-PGNLSATIQAYAALLVSKMYKEDI---NM
KRAEVFIRKQGGITKAHFMTKFLLALHGGYEYPPLFHFPTPILFLSEDSPLSIFELSSSARIHLIPMMLCMNKRFVSKM-LP-----DYISGGSKE--W-
----------F----PLF--QTLLRDVT-------LS--PLSLHYKGDKAAERFMIERDTNGTLYSYASATFIYALLALHSIQS--PLISNAVLGLKTYV
WNMD-WAHLQNS-PSTVWDTALLSYSLQEARVPH-DNEMIQKAINYLLQKQHK--EKKDWSVAPTLDAGGWGFSDVNTTIPDVDDTTAVLRALAGSRQG-
----N-PKVESAWRKGIEWVKGLQNSDGGWAAFEKGVTSKV---LTPLDNSGDMITDPSTVDITGRVLEFFGTYAPN----E--LQGDQKDRAIRWLIYT
QEKNGSWHGKWGVCYIYGTWAALTGLRAVGVPSN-HIALQKAATWLESIQHSDGGWGESCRSSVEFISLP--FSTPSQTAWALDALIACYD--E-TPTIR
KGISYLLKHSTK----HQEYPTGALANGFYIRYHSYHHIFPLLTFAHYIKKYRK---
>tr|A0A073K6T1|A0A073K6T1_9BACI Squalene-hopene cyclase OS=Bacillus gaemokensis GN=BAGA_20405 PE=4 SV=1
---------------------------------------------------------------------------------------------VREEVER
KITALRTMQQQDGTWRFCFEGSPLTDCHMIFLLRLLGQ----K---EIEPFVVRLASLQTNEGTWKLYED-PGNLSTTIHAYAALLASRKYKEDI---NM
KRTAAFIRERGGIVRAHFMTKFLLALHGEYEYPSLFHFPTPILFLPEDSPLSIFELSSSARIHLIPMMICMNKRFVSKI-LP-----DHITGGSKT--W-
----------F----PIF--QTLIGDVK-------LA--PLSLHHKGYKEAERFMVERDKNGTLYSYASATFIYALLALHTVQS--PVINRAVAGLKSYI
WNME-GSHLQNS-PSTVWDTALLSYSLQEANVSQ-DNHIIQKATEYLLQKQQH--EKKDWSAAPLLDAGGWGFSEINTTIPDIDDTTAVLRALARSTKG-
----N-QKVEEAWKKGIEWVKGLQNIDGGWAAFERGVTSKF---LTPLDNSGDMTTDPSTSDITGRVLEFFGTYAPD----E--LTNDQKNRAIRWLVHA
QEKNGAWYGKWGVCYIYGTWAALTGLRALGVPST-DIALQKAVAWLESTQHRDGGWGESCRSSIEFVSLP--FSTPSQTAWALDALIAFYD--E-TPAIR
KGISYLLAHSTE----HQEYPTGGLPDGFYIRYHSYHHLYPLLTFAHYIKKYRK---
>tr|R8T975|R8T975_BACCE Squalene-hopene cyclase OS=Bacillus cereus VDM021 GN=KOY_03783 PE=4 SV=1
---------------------------------------------------------------------------------------------VREKVKK
EITALQAMQQQDGMWCFCFEGSPLTDCHMIFLLKLLGQ----Q---EIEPFVARLASLQTNEGTWKLYED-PGNLSATIQVYAALLASKMYKEDI---NM
KRAEAFIRRQGGITKAHFMTKFLLALHGGYEYPSLFHFPTPMLFLPEDSPLSIFELSSSARIHLIPMMICMNKRFVSKI-LP-----DYISGGSKK--W-
----------F----PLF--QTLLGDVK-------LL--PLSLHHKGDKEVERFMIERDTNGTLYSYASATFIYAFLALHSIQS--PLISNAVLGLKTYV
WNMD-GTHLQNS-PSTVWDTALLSYSLQEAGVPH-DHQMIQKATDYLLQKQHK--EKKDWSVAPSLDAGGWGFSDINTTIPDIDDTTATLRALARSRKG-
----K-QKVEEAWKKGIEWMRGLQNIDGGWAAFERGVTSKV---LTPLDNSGDMVTDPSTPDITGRALEFFGTYAPK----E--LQGDPKDRAIRWLIHT
QGKNGSWHGKWGVCYIYGTWAALTGLRSIGVSSN-HIALQKAATWLESIQHSDGGWGESCRSSIEFISLP--FSTPSQTAWALDALIAYYD--E-TPVIR
KGISYLLTHLTQ----NQDYPTGGLPDGFYIRYHSYHHIFPLLTFAHYIKKYRK---
>tr|M5QXE7|M5QXE7_9BACI Squalene-hopene cyclase OS=Bacillus stratosphericus LAMA 585 GN=C883_2400 PE=4 SV=1
---------------------------------------------------------------------------------------------VNEYIDE
LHMQVERRQREDGAFIFCFEGPMMTNAFFIMLLKAVG-PDQ-Q---LIHQLAEAIHAKQNEDGSFSLYHD-SGHLTATVQGYCGMLASGRFKDEP---HM
EKAAQYIRSKGGLKNVHFMTKWMLAVNGMHPWPYFY-APLSFLLIPTSFPLHFYHLSAYARIHFVPMMIALNKRYTS-H-AAP----AHLDENMSKPFD-
---------------STD--DFLMY-M--------RSY-DSRLDFFGYEAAKRYMFDREKDGTLYSYLSATIVYALMSLYSPGH--HLIQKAVRGMKKLV
TSCQK-IYAENS-TSTVWDTALVSYASQRAGRKR-EDPMIMNSFTYLIDRQQM--KKADWAVNRHAAPGGFGFSHINTNNPDCDDTQIVLKALPKEY---
--------APLQWKRGYDWLLSMQNRDGGFSAFEKNQDHFL---LRPLESAEDAAIDPSTPDITGRVLHLIGLEEKDT--AS-PTILRQKDRCVKWLIDH
QEKNGSWFGRWGVCYIYGTWAALTGLKAAGIPSS-HPAVQKACRFLKQIQLEDGSFGESCKSAELYVPLS--FGTVVQTAWATEALLQYEKN---NAAIL
KAVSFLVNH--HHTEEAMYYPVGGLPKQFYITYHSYPFVFPMMACSTFLEEMRRI--
>tr|A0A061NT73|A0A061NT73_9BACL Squalene-hopene cyclase OS=Geomicrobium sp. JCM 19038 GN=JCM19038_1589 PE=4 SV=1
---------------------------------------------------------------------------------------------VSEGIDQ
LIQTVRADQSEDGSWRYPLESGTFTDAYMIILLRTLERDDE-A---LIRGLTNRLIKKQEPNGAWKLFADNTGNVTNTVEAYYALLYSGYYEDDE---RM
KRARQFIMKSGGIQKTAFLTKIVLTLTGQYKWPSFFPFPIELILVPDFFPINLYSMSVYGRAHVVPLILAADQKLQVKT-AQP----SDLFASRGE----
---------------RMH--ASIVQRV--------KRL-PQELHLLARSRAKLYMTNGEEDGTLFSYFTSTMIFGLLALHPKDD--PIIEDALEGLYGFQ
TTIDGHPHFQFT-TATVWNTALLSYALQEAGVRT-DDRMIERANDYLLDRQQE--GYGDWAMNKKVLPGGWGFSDVNTFQPDVDDTTAALRALARNA-KE
---NQ--DIFESWNRGVRWTISMQNHDHGWSAFEKNTDSWL---LAPIPESRGILTDPSTPDLTGRTMELLGNYTDV----K--GGDMILRKAVKWLERE
QEKDGSFKGQWGVNYLYGTWAALTGMQASGVGRE-DKTAKKAIGWLKEKQNGDGGFGESCLSDRYYTPLD--SSHLTQTAWVLDALVAMYDP---NKTMY
DALHYVLDRLG-DGQWPRSYPAGGLADRIYFHYHSYEYIYPLLALAHYRKKYGDS--
>tr|W4BAJ8|W4BAJ8_9BACL Squalene-hopene cyclase OS=Paenibacillus sp. FSL R5-808 GN=C169_08868 PE=4 SV=1
---------------------------------------------------------------------------------------------VQTEIQT
YISHLKSLQFPDGSWRFLFETGPMTDANMIILLKNLD-TKP-E---LIPQLAQRLKQRQAPNGAWKQYDDV-GHLSSTVEAYTALLLSGCAREDV---MM
QKAEEYIIQHGGVEQAHVSTKFMLALNGFYPWPRFFPLPLYLIQLPKSSSFSYYRWSSYVRSHFASLLILGHRKFKLHH-PPI----HHLFVTQHFKLR-
------------------------SNR--------TRE-KGYLSRSALKKTELILLQNENDGTQYSYASATFIYSLLAIYKTDS--PMIKQAVEGLVSFG
YTALGSLHIQNS-PSTVWDTALIAYTLQEAGVST-EDAAILRAAKYLLSLQHL--EKQESERSRHRTSGGWGFSESNTANPDVDDTQAVIRVLTRLA-AQ
---QS--EYSAAWRKGIQYVFRMQNDDGGWAAFEKNSASSI---IRRIPHFAETASDPSCADITGRVLELLGNHLKL----R--LSHPRIQDGLDWLVKK
QKSDGSWYGRWGVSFIYGTWAAVTGMAAAGLQAD-HPAIRRAVDWLLRIRHEDGGWGESCRSDFIYNPAP--YSTVVHTAWALDALIAVHDP---TEVID
QGILRLIEWN-RQEGRRTTYPAGGLPGHFYIHYHSYPLVWPLLTLSHYVQKYQKQ--
>tr|W8ZQV1|W8ZQV1_9BACL Sporulenol synthase OS=Paenibacillus sp. P22 GN=sqhC PE=4 SV=1
---------------------------------------------------------------------------------------------AKETAER
LREELLERQSPDGAWRLCCESGVMSDAFLLILLKAMDWDHR-E---LARRIAQRIAVLQEDGGGWKLHEDKEGHLESTVEAYYALLATGYYYGDP---RM
VNARRFILALGGLGEVTMMTQVLLCMTGQLDWPRVLRIPVETLLAPSWLPLSLFDLSGHARVHLVPVLMLASGSFKLGD-GRP----SELVAGESRFLK-
---------------GPL--AGMAEAL---------AA-PL--YPASLDKGEKFMLDREPNGTLLTYSTATIIAALVSIYPPSH--EVIRRGLDGIRSLV
WDDPEISHLQIA-SSTVWDTAMLGCVLHESGLSA-DHDALQRAAGYIASRQQT--AKGDWARNPRTPPGGWGFSDVNTRYPDIDDTTASLSMLQRIP-AA
---DA--FPDEARERGDRWVWSMQNKDGGWPAFERESGSPL---IGQFEQASQIVTDPSTVDLTARTLAWSSRR-N-----D--PAPSWVVRAAAWILKQ
QQRSGCWPGRWGIAYVHGTGAAITGLMAMRAKRS-ASALYRGMNWLLSVQNADGGWGESCFSDVAYRALG--ASTPSQTAWALEGLMAHPSP---PVAID
RGIECLIELLEADD-WRSRYPTGGLPGHVYLNYHSSRYIWPLRVLSAYAASAASK--
>tr|A0A0D5NL07|A0A0D5NL07_9BACL Uncharacterized protein OS=Paenibacillus beijingensis GN=VN24_17045 PE=4 SV=1
---------------------------------------------------------------------------------------------VRQMKET
LVRELLNSQSGDGSWRLCFEGGITSDAYLIVLLCSLK-PDP-G---LIRKLAARIASRQEPGGGWKLYRDPDGQLEATVEAYYALLYSGYYPDHP---AM
EQARSFILARGGLCRVTLLTQALLCMTGQAEWPGSLRIPVETLLAPLWFPVNLFDLSGHARVHLVPILMIASTGFALHS-GEP----SGLFVGGERFDD-
---------------PSL--SALFKGL---------SS-LL--HKPSLRKAELFLLEREPDGTLLTYSTATMIAALLSIYEAGS--DIIQRALAGIKSLV
WQWEHTAHLQVA-SSALWDTAMIGCSLRDAAGGLEADRAVRRAADYVAQRQHN--RKGDWSINPYTPPGGFGFSDVNTLYPDVDDTMAALHLLRPFA-KT
---DA--NLRRQWERGLAWVLSMQNPDGGWPAFEKESDSPL---LGQFESAAHIVTDPSTVDLTARTLHVLSKG-D-----P--AG----AKAARWLLER
QLQDGSWFGRWGICYVHGTGAALSGLSAIRAGGR-ASAVARGTRWLLSVQHPDGGWGESCASDAAYVPLQ--GSTPSQTAWALEALIAVHSP---TASID
NGIVRLIELLQAED-WRSSYPTGGLAGSLYIHYHSSRYIWPLRVLAMYERRYGSP--
>tr|C6CW86|C6CW86_PAESJ Squalene/oxidosqualene cyclase OS=Paenibacillus sp. (strain JDR-2) GN=Pjdr2_1272 PE=4 SV=1
----------------------------------------------------------------------------------------------------
MRSELLQLQSADGSWRLCFDSGTMPDSYFIIILRMLGY-DE-A---LIRQIASRILSRQLPNGTWKIYPDEDGNLDATAEAYFALLYSGFLKLDP---RM
QLAKQFILSKGGLSKISLLTQAIFAAAGQASWPKSMRIPLEVFFSDNGIGIDLFSLSGHARVHIVPIIMLANAQFVQHS-ASP----SDLFAGSSKFEN-
---------------AAL--ATLIGSL---------SL-LPFESPTPQEKAVQFLFDREPDGTLLTYTTATMILVLLMLYSSSS--PLIHRMVSGIHSVI
CANS---HVQIA-SSEVWDTAMLVHALRKAGVNP-TSTALENAGAYLRQRQQT--QLGDWAINPGTPAGGWGFSNVNTLYPDVDDTTAALRAIQPYS-SR
---TP--ELQADWQRGLNWVLTMRNDNGGWPAFERQGSRLP---ITNFEGAKDIAVDPSTVDLTSRTLQFLGQELGM----N--AGNSWIESTLRWVLSQ
QESNGSWYGRWGITYVHGTSAALQGLTAVGIAED-HPAVKKGVDWLLQVQNEDGGWGESCISDKVYVPLN--FSTPSQTAWALDGLTAALPP---TPALE
RGVDALLQSLDRHD-WTYTYPTGALPGSVYAHYASNNYIWPLLALSNIWQKYS----
>tr|E0I6P7|E0I6P7_9BACL Prenyltransferase/squalene oxidase OS=Paenibacillus curdlanolyticus YK9 GN=PaecuDRAFT_1319 PE=4 SV=1
---------------------------------------------------------------------------------------------LRHRIDT
MANQLLADQSPDGAWRMCIDCGTMSDCYYLTALRLLDV-DD-P---LVRSLAARIVSRRSPDGVWRLFPDREGSLDATAEAVLALLLSGVYDRDP---II
VSAKRFIREQGGLAKVSFLTQALLCAAGIALWPRSLQIPLSAFFNKSGPLPRLFELSGHARVHLIPILIMANKRYALRT-AYP----SDLFLGAPPFDN-
---------------AAL--NNLIGAF---------S--LTGGNDSLYEPAVTFLLEREPDGTLLTYSTATVLFALNAVRLPTD--PILISAINGIRTLL
CGNP--PMVQIA-TPTVWDTAMLAFALREAGISP-SHSALRRAARFIQERQQT--RYGDWRINPGTSPGGWGFSYVNTRYPDCDCTTAALRVIQRSH-GS
PTGHA--AAAEPWERGLNWLLSMRNDDGGWPAFERNGKPLP---AGGFNGASEILTDLSTPDLTGRTLQMLGETLGM----S--TQQRWLSSSARWMLSQ
QQKDGSWYGRWGITYTHGTGAAVLGLTAIGLTPD-HPAIARAVKWLLSIQRPDGGWGESCYSDQRYVPLN--FSTPSQTAWALDALAASLPL---TPELE
RGVNALLHMLETPAQQLTRYPTGGLAGTVYVHYESNNWIWPLLTLTRIERKFRRQ--
>tr|A0A024Q9F5|A0A024Q9F5_9BACI Sporulenol synthase OS=Virgibacillus sp. Vm-5 GN=sqhC PE=4 SV=1
---------------------------------------------------------------------------------------------IGSKINE
LVDELKEKQRPNGSWNYPFETGVSTDSYMIILLRSLEIDDH-D---LIWSLAERIANKQGPNGAWKLYYDGGGNLTATVEAYYALLYSGFYRNDR---HM
RLAKRFIMNKGGLSRIHLFTKIMLALTGQLQWPNHIPIPIESLLLPASFPINFFDLSMYARAHLTPILIIADKKIQVTT-PLP----TELSMKRTEW---
---------------SIF--SLIKQAI--------AKL-PHELHNLALRQAETYMLQREPDGTFYSYFSSTFIFALLARYAKNH--PVIQRAVAGLKTFI
ISINNQPHIQFT-TATVWNTSLISYSLQEAGLSS-SSETIHKAAQYIRSKQHH--LYGDWAISPHVLPGGWGFSNINTINPDNDDTTAALRALRTSV-LD
---KN--TNRFIWDRGIEWLLSMQNGNGGWGAFEKDIDSPF---LSPVKGAELILLDPSTPDLTGRTLEFLGLYTKL----N--QSHPFMKRAVNWLIKN
QQKDGSWYGRWGICYIYGTWAAITGLIAAGVDRE-HSSVKKAIDWLYQIQNEDGGWGESCKSDQAYIPLQ--TSTKTQTAWALDTLIAAEDV---TIELK
QGIHFLLKEQENKDKWTKEYPKGALPGNFYMHYHSYEYIFPLLAFAHYRKKFIEE--
>tr|A0A0D6ZER0|A0A0D6ZER0_9BACI Squalene-hopene cyclase OS=Bacillus subterraneus GN=UB32_02005 PE=4 SV=1
---------------------------------------------------------------------------------------------VNKEMNR
IVKQLIRDQSKDGAWRYPFETGIATDCSMIILLRTLEIEDE-A---FIKELVERIAGEQQEDGSWKLFHDKNGNLTSTVEAYYALLYSGYRRKDK---DI
QAARRFILANGGAGEVHQFLKIMLALTGQCEWPH-FPINIEVMLIPDTFPINLFDLSVYGRANIIPFLILANTNFRKRT-AQP----SDLFQNREVL---
---------------SLT--KWVKQGI--------NGL-HGNLRELALYRAEKYMLDRESDGTYLNYFSTTTIFALLARYHSTH--PVITRAVQGLKAMT
TRMDDKLHCQYT-TATVWNTTLISYVLQESGFAY-SSSPVQKANQYILSRQQL--KYGDWAIESTVLPGGWGFADLNTFHPDIDDTTAALRAIRTLA-TE
---QV--DYRQAWDRGVNWLISMQNKDGGWAAFEKNVDKKV---LNPVEGGQDLLIDPSTVDLTGRTLEFFGNFTNL----D--FHQPMIKAGVRWLLQQ
QQTDGSWLGRWGV-YIYGTWAAVTGMIAVGISPK-HPAIQKALTWLRKIQNPDGGWGESCNSDIQYVPLG--DSTRTHTAWALDTLISAATV---TSEME
NGVAFLVDRK--EKDWTSTYPKGGMAGSFYINYHCYEYVFPLLALAHYQKLTDGQ--
>tr|A0A098F7V6|A0A098F7V6_9BACI Squalene--hopene cyclase OS=Bacillus simplex GN=BN1180_00412 PE=4 SV=1
---------------------------------------------------------------------------------------------VQSEINR
LVHRLKQDQSADGSWNYPFDTGITADAYMIILLKILDMEDT-P---LIEALVKRIESKQTENGSWKLFQDKDGNVTVTIEAYYGLLFSGLRKNHP---HM
RKAKQFILSKGGIKQAKMLTKMMLTVTGQYQWPRLFPIPLEVVLLPPTFFVSIYDLSVYGRVNMIPLLLLGHKKFQITT-PDP----KDLFQTREDSEE-
---------------SFF--SKLQTGV--------KTL-PDYLHSLALDSTKRFMLDREPDGTLYNYFGSTFIFALLSIYSKRD--PVILKAIAGLKGMA
CSIEGHTHIQFT-TPHVWNTSLISYALQEAGMPF-KDKAVKAANQYLLSRQHY--MYGDWLINPDAIPGGWGFSDLNTMNPDVDDTTASLRALAKQL-QA
---KP--DNRDSWQRGVAFTISMQNDDGGFPAFERNNDHKW---LQPIEGSKYLLTDPSTADLTGRTLEFLGNYTNM----K--KPEEVSKRAVDWLLED
QKRDGSWYGRWGICYLYGTWSALTGMKAAGQATG-HPSIQKALTWLKKIQNEDGGWGESCYSDIKYIPLG--TSTLTHTAWAVDALISASEP---TAEIE
KGIAYLIRAG-QQESWTNDYPAGGMADFLYIHYHSYRYIYPLLALSHYNKKFLET--
>tr|W1SGL3|W1SGL3_9BACI Squalene-hopene cyclase OS=Bacillus vireti LMG 21834 GN=BAVI_13934 PE=4 SV=1
---------------------------------------------------------------------------------------------TRKGMDW
IINVLRKDQSPDGSWSYPFDTGISTDAYMIILLRTLEINDE-E---LIQGLTKRILSRQEKNGAWKLFFDGDGNVTATLEAYYALLYSGYYKNDK---RL
RTAKKFILANGGIKQASTYTKIMLAITGQQKWPTFSPFPIEVILLPEVFPLNFYSFSVFGRANLTPIMILADKKLSIRT-SLP----SELHLHRDED---
---------------SLL--SFLDDGV--------KSL-PKELRRLAIERAKKYMLDHEADGTYYSYYSCTFIFALLSLYKKTD--PVILKAIEGIKSMK
CEINGLPHMQYT-TANVWNTSLIGFALQTAGIPI-TDPMVVNANRYLLDRQHH--KFGDWVINPNSLPGGWGFSNVNTILPDVDDTTASLRSIARIV-PT
----E----LAAWERGINWTFSMQNDDGGWPAFEKNADSKL---IEPLEEAEFLLMDPSCADLTGRTLEFFGNYTNL----S--RDHTAIKKGLKWLMKD
QKRDGSWYGRWGICYLYGTWGAVTGLSAVGVPNS-NPSIQKAAGWLRSIQNEDGGWGESCHSDSAYIPLR--TSTLTHTSWALDALITMSEP---TSEIR
KGIQYLLDSL-DKDDWTTAYPKGGMGGAFYIHYHGYRYIFPLLTLAHFQKKFEQK--
>tr|K6DBR4|K6DBR4_9BACI Squalene-hopene cyclase OS=Bacillus bataviensis LMG 21833 GN=BABA_18417 PE=4 SV=1
---------------------------------------------------------------------------------------------VYKEING
IANQFVQDQSEDGAWRYPFETGIATDCSMIILLRTLEINDE-E---FIKELVKRIAGKQQEDGSWKLFHDEKGNLTSTVEAYYALLYSGYRLKDQ---EI
QAARRFIMAGGGAAEVHMFLKLMLAITGQCAWPH-FPINIEVMLLPDSFPINLFDLSVYGRANIIPFLILANTNFRKRT-PRP----SDLFQKKEVF---
---------------SVI--KWIKQGI--------KGL-HVNLRELALYRAEKYMLDREPDGTYLNYFSTTSIFALLARYSNTH--PVITRAVQGLKAMT
CRIDGELHCQYT-TATVWNTTLINYALQESGVPY-SSNTIQTANHYILSRQHL--KYGDWAIEPNLLPGGWGFADMNTIHPDIDDTTAALRSIRTLA-IE
---QV--DYRQAWDRGVNWLISMQNNDGGWAAFEKNVNKKV---LNPIEGGKDLLIDPSTVDLTGRTLEFFGNYTHL----D--YHHPMVKRGIRWLLRQ
QNSNGSWVGRWGV-YIYGTWAAVTGMVAVGVSTN-HPAIQKALTWLRNIQNPDGGWGESCKSDIKYVPLR--ESTRTHTAWALDTLIAAATV---TPEIE
NGAAFLVDKK--EKDWTKTYPKGGMAGSFYLNYHCYEYVFPLISLAHYQKLAGGQ--
>tr|W1SMW7|W1SMW7_9BACI Squalene-hopene cyclase OS=Bacillus vireti LMG 21834 GN=BAVI_02644 PE=4 SV=1
---------------------------------------------------------------------------------------------VNAEINR
ITDQFIKDQSDDGSWQYPFETGIATDCSMIILLRTLEINDE-E---FIKDLVKRIAGKQQEDGSWKLFHDEKGNLTATVEAYYALLYSGYRRKDQ---EI
QAARRFIMANGGATEVHMFLKIMLAITGQCEWPH-FPINIEVMLLPDSFPINLFDLSVYGRANIIPFLILANTNFRRRT-PRP----SDLFQNKAVF---
---------------SVI--KWIKQGI--------KGL-HVNLRELSLYRAEKYMLDREPDGTYLNYSSSTLIFALLARYSNTH--PVITRAVQGLKAMT
CRIDGELHCQYT-TATVWNTTLISYALQESGVPY-SADTVQKANQYILSRQHI--KYGDWVIDPNLLPGGWGFADMNTIHPDIDDTTAALRAIRTLA-IE
---QV--DCRQAWDRGINWLISIQNNDGGWAAFEKNVNKKI---LNPIEGGKDLLIDPSTVDLTGRTLEFFGNYTHL----D--FHHPMVKRGIRWLLKN
QNSDGSWVGRWGV-YIYGTWAAVTGLVAVGVSPN-HPSIQKAVNWLKAIQNQDGGWGESCKSDIDYVPLC--ESTRTHTAWALDTLISAATV---TPEIE
HGAAFLVDGK--EKDWTKTYPKGGMAGSFYLNYHCYEYVFPFLALAHYKNLAEGS--
>tr|A0A060M1B6|A0A060M1B6_9BACI Squalene--hopene cyclase OS=Bacillus lehensis G1 GN=BleG1_3670 PE=4 SV=1
---------------------------------------------------------------------------------------------IQAAIDT
LVSKLREDQLEDGSWQYPFEAGTFTDAYMIILLRTLEKDDE-T---LIQALAERLLSLQEENGAWKLVKDNEGNLTTTVECYYALLYSGYLKNDQ---RL
QKAKQFILTNGGIEQTTLLTKFVLLLTGQYKWPSFFPVPIELILLPVAFPFNLFSMSVYGRAHMVPLLIAADHKLQVTT-SRP----SDLYSQSRNP---
---------------KLH--GTIHYLV--------KKV-PTNIHQLAISQAKRYMMNAEQDGTLFSYFTSTMVFALLALHPKHD--PLIEKAMEGLKSFQ
TTVNGKPHIQFT-TATIWNTSLISYALQEAKVKP-SDEMIQKASSYLVQKQHN--TYGDWIVNPGILPGGWGFSTINSIQPDMDDTTSSLRAITAQA-VE
---NE--EIKEAWKRGTLWVTSMQNRDGGWGAFEKNTNSRL---LAPIQESKGILTDPSTPDLTGRVIEFLGNFTHV----P--KDEKVLKRGIRWLKRN
QQKDGSWEGQWGVNYIYGTWAALTALDAAGVSKD-EPHIRKAVNWLKSIQHQDGGWGESCLSDRNFTKLP--ASNLTQTAWAIDALIATLDP---EKSIR
DGVRYLLAHLHTSSDWTNAYPVGGLADRIYFHYHSYRYFYPLLALAHYQNKYNQS--
>tr|A0A0A1MQ41|A0A0A1MQ41_9BACI Sporulenol synthase OS=Oceanobacillus oncorhynchi GN=sqhC PE=4 SV=1
---------------------------------------------------------------------------------------------IDVEINR
LVDRLTKEQEHDGSWAYPFETGISTDCYMIILLRTLEMDDE-D---LIDALVSRILRKQGKNGAWKIFHDVEGNLTATVEACYALLYSGRREEDR---EI
RLATKFIQRHGGLKEINMFAKVMLALTGQYKWPRYLPVPVKFILFPVSFPLNLFDLSLYARSNLVPILITADYKFSRKT-KRP----SDLFLQREDG---
---------------SFQ--TPFGREI--------SSL-PEQLHELALQRAEEYMLNRESDGTFYSYFSATFIFALMARYSKKD--PIIIKAVEGLKAFQ
TSIGKQTHMQYT-TANVWNTALISHALQKAGVSP-SATVIKKANQYLLGRQQM--KYGDWSINQDVTPGGWGFSHINTFNPDLDDTTAALRSIRSFA-RH
---TP--VYRQAWDRGIQWAVSMQNDDGGWPAFEKNVDNTL---LSPIEGGGSMLLDPSTADLTGRTLEFFGNDTHT----D--TYQPFIKRGMKWLLQN
QEKDGSWYGRWGICYIYGTWSAITGLAAVKTRSN-HPQMQKAIQWLYAIQNQDGGWGESCKSDIEYVPLK--ESTRTHTAWALDALIAAEGA---TPEIK
RGIAYLLETA-EKVDWTTAYPKGGLPGGFYIHYHSYEYLFPLLALANYREKF-----
>tr|A0A0C2UEM2|A0A0C2UEM2_BACBA Strain MTCC 1458 Contig9, whole genome shotgun sequence OS=Bacillus badius GN=SD77_3974 PE=4 SV=1
---------------------------------------------------------------------------------------------VYKEINS
IANQFVQDQAEDGAWHYPFETGIASDCSMIILLRTLEMNDE-E--ELIKELVERIVGKQQEDGSWKLFHDDKGNLTSTVEAYYALLYSGYRPKDP---EI
QAARRFIMVNGGATEVHMFLKILLALTGQCAWPH-FPVNIEVLLLPDSFPINLFDLSVYGRANLIPFLILANTNFRRRT-PKP----SDLFLKRKVF---
---------------SVI--KLIKQGI--------KAL-HGNLRELTLYRAEKYMLNREPDGTFLNYFSSTTIYALLARYSNTH--PVITRAVQGLKAMT
CRINGELHCQYT-TASIWNTTLINYALQEAGIPY-SSNMIQKANHYILSRQHL--KYGDWVIEPNLLPGGWGFADMNTIHPDIDDTTTALRAIRSLA-IE
---QV--DCRQAWDRGVNWLISMQNNDGGWAAFEKNVDKKV---LNPLEGGKDLLIDPSTVDLTGRTLEFFGNYTHL----D--DHHPMVKRGIRWLLRH
QNADGSWVGRWGV-YIYGTWAAVTGMIAVGVSRN-HPAIQKALAWLRKIQNPDGGWGESCKSDIKYVPLG--ESTRTHTAWALDTLISAATV---TPEIE
NGAAFLTDKK--EKKWTAAYPKGGMAGSFYINYHCYEYVFPLLSLAHFQKLAGGQ--
>tr|S2XIF1|S2XIF1_9BACL Squalene-hopene cyclase OS=Paenisporosarcina sp. HGH0030 GN=HMPREF1210_01421 PE=4 SV=1
---------------------------------------------------------------------------------------------LSDEINR
IISILKKDQSEVGTWDYPFETGITTDAYMIILLRSLTIDDE-K---LIKELVDRILSEQQDSGAWKLFYDDDGNVAATIEAYYALLYSGYCHDDV---RM
QVARQFILSNGGIDKSNLLTKIMLAVTGQFSWSKIFTVPTEFVLLPHSFPMNFFDFSVFGRANIAPLMILADKKYIIKT-NKP----SDLYILNHNWDE-
---------------PFL--LSIQKRI--------EDL-PKQIEELAVDKTKQYMLEREPDGTLYSYFSSTFIFALLSLYKKDH--PTIIHAVNGLKSMK
CQVDGKTHMQFT-TATVWNTALISYAMQEAGVSE-LDPVIKKANQFLLTRQHY--KYGDWVISPHSLPGGWGFSNVNTMNPDIDDTTASLRSICKTV-IK
---KP--KVHTSWDRGINWVFSMQNDDGGWPSFEKGVNKSI---LSPIEDAEYLLADPSSADLTGRTLEFFGKFTNL----K--KSHDSIKLGVNWLFDH
QEPNGSWYGRWGICYIYGAWAAITGLVAAGISSD-HPSILKSVKWLRDIQNSDGGWGESCKSDKMYVPLG--ASTLTHTAWALDALIAAEDL---TPEII
SGIKYILENN-DKDDWTTSYPKGGMAGSFYIHYHSYRYIFPLIALAHYQKKFPNE--
>tr|H6CKD8|H6CKD8_9BACL Squalene-hopene cyclase OS=Paenibacillus sp. Aloe-11 GN=WG8_3101 PE=4 SV=1
---------------------------------------------------------------------------------------------VQAEINR
YMTRIQSEQQEDGSWRYDFETGPMTDASMMILISSLYPEEQ-E---LLSKLAQRLVYKQADGGEWKQYDDD-GHLSSTIEAYTALLLSGYLRDAP---PM
KRAKDYILRSGGVEKAHVSTKFMLALNDLYPWPAYYPMPLFLIHLPKWIPFSFYRWSSYVRTHFAPILILVHLKFTLPH-PSA----SHLYTTPKYKLH-
------------------------G-----------RR-KGKRSNRSIQKAESFIFEHEGDGTLHSYASATFIYALLAIYQPDS--PVISRAMKGLLSFV
TKTDGGMHIQNS-PSTVWDTALASYTLQEAGLSA-GDHTVQRAAAFLLSLQHT--EKKAQAESLLHMTGGWGFSESNKANPDVDDTQAVLRALTRYT-SY
---HA--DSLESWRKGVQYLFRRQNDDGGWAAFERNSTSFM---TRAVENFEDTAFDPSAADVTGRTLEFLGNHVKL----T--TNHPRVQAGVRWLLKR
QQRDGSWYGRWGVSYLYGTWAAVTGLRAVGLSAE-HPAIQQAADWLLRMRQPDGGWGESCKSDVAYIAAP--YSTVVHTAWALDLLIAVHDP---VKEIK
EATSLLIDWN-REEGSRVTYPTGGLPGHFYIQYHSYPRIWPLLTLSHYEQKYKDC--
>tr|T0CIK5|T0CIK5_9BACL Uncharacterized protein OS=Alicyclobacillus acidoterrestris ATCC 49025 GN=N007_20175 PE=4 SV=1
---------------------------------------------------------------------------------------------IRRQIAA
GAAQILSHQRADGAFSYGCELSPFTDAVMMIFLHLMGEADD-L---LVSELSETVAQAQKPDGRFVAYPD-TDNVSLTTLCYFALRLSRYSSS-G---RE
DKTRQYILQHGGIRHTSNLTKIILACAGQLSWRELPPPFIDVVLWGTRAPVNLYDFASFTRLHMVPFMLLSHLEYQVPV-PEC----ADLVVPSFGPY--
-----------------------------------V---LPFDHPKAVAAARQFILDREENGTLASYHLATVVLALKAVDPDDA--DVIASAVAGLKEMV
SRHDDRVYQQQF-TSTVWDTALSMRALAATRLPA-CSEALARGAEYLLERQHV--DVGDWAVAPKAKPGGWGFSDMNTKYPDVDDTVAALKALHPYQ-P-
-------QCRVAWRRGVKWLLAMQNEDGGWSPFDHNANKAW---LEPINDMGRAMTDASTADITGRVLETIGSTGI--------RAQPAVTQAVQWLITN
QRENGAWFGRWGVTFIYGTWAAVRGLRAVGMPRD-TTTLQKARAWLESVQNADGGFGESCASDQRYCPLG--WSTVSQTAWGLMALMSASPL---TDPIR
RAVAYLLQCGAKPGGFVESYPTGAVAGQAYIRYHSYPQVWPLLALCMYVDRFRQH--
>tr|H3K1N9|H3K1N9_9EUKA Squalene-tetrahymanol cyclase OS=Trimastix pyriformis PE=2 SV=1
---------------------------------------------------------------------------------------------IIDVVNQ
TATLLAHK-RADDSYSYPPYLGSNYISQYYIMLQWLNAFQTEL---NESRLAEVLFDQQLADGSWQAVTDLPGEVDTTIFNYWALKAMGYPT-HA---RL
TAARSYILAKGGLLKAT-MTRFWLALFGNVAWETVSYVPLFVF-Q--GDIVDVDRVSQWVYPHLLPMAYLRATRLVRPM-PEF----HELLLSAKIANGV
---------LP---P-----RQNYYEN-AL----YDG--LKDVSTKELQALVDRMFKVRPAGSFGAYTVSTLVVCLQD-FAHRDAEAATRGAFPFIELYL
KSGP-AYLGVLD-YGDYWDSMLAGLALMDVAAD-PNR--VLPTANYLASKLVTL-KGPMS-G--LGIPYGLDF----EYAPDVDDTAEVAILYSRLLAAN
A-TGA-QPLAPLRQGLLGWLQAMQNDDGGWGAFNRNRQGWWLVE-VQFADSAEL-FDPSTVDVTAHIMEAFASVGQT---AA---NSKSVQRAVAYLRTQ
QQKNGMYPGRWGIGYVYGTGAALVGLRKAEVPS-D-PACLRAAQWLLDVQNHDGGWGETSYSYKD--AGKG-LSTVSQTAWALLGLLELRDLPALAAAIE
RGVGYLVADF-RAGGFNDRSAVGGHPGIIYMQYPVYAQTWPLMLLGRYLARSQ----
>tr|A6FWU9|A6FWU9_9DELT Squalene cyclase family protein OS=Plesiocystis pacifica SIR-1 GN=PPSIR1_04883 PE=4 SV=1
---------------------------------------------------------------------------------------------LRAGYER
ALGALERAQQARGAWAGEVVWNPMLICQYVIAMHVLGRAERRR---NI---RRQLEVTRKRDGGWGMHPDERPKMFHTVLGYVALRLLGDARTAA---ML
EESLAWIHAHGGPERA-TWGRIWLALLGLYPWDLVQPLLPELWLLPDYCHMRLYLWGAPSGPVLDALAAELYPGGSRAF-EAR----DDIAPTDL---FE
----------P---V-----LDRATDL-PL----LRP--LAALRRRALDRAWAHIEF-FHSTDWVCLSPVNGLFCLAMAR----DLDRALAGLEYWV--W
EDAE-GARICGA-RSDIWDTSFALQALAEGPEL-EGRALAQRAAAWLPKAQVMR-ELSTAPGLP--TRGGWGFADERHPWPVSDCTAEALEALLHVEARG
WIQATPALSPARKLAAAEFILLRQNDDGGFGSYEERRGSMALIHFNAEMYGNCM-LEYSYAECSASCVRALAVLREREPGDLRARVDAAVDAGVRFLLEA
VDKAGAWRGFWGVNYTYGTYFAVSALLAAGVE---HLVVRRAVRFLLDRQRADGGWAEDYRGLLE-LADDE-ASRVTQTAWAVATLALAAP--RARQSVD
AGLAYLLERQQA-GTWEHDASVGFF-NTAVLDYRLYRQVFPTWALARCLEDHHLK--
>tr|A0A084H5Q7|A0A084H5Q7_9BACI Squalene-hopene cyclase OS=Bacillus sp. SJS GN=AS29_20530 PE=4 SV=1
---------------------------------------------------------------------------------------------AELELLY
LTEKLKNEQLPNGSWSYLFETGIKTDCFMIVLIKALRLYKP-D---LLNSLSERIARKQERDGSWRLFHDEEGDVSTAIEAYYALLLSGYYETAP---QM
IAAKRYIISKGGIRKAGLFTRIMLALTSQAEWPSLLSVPIEAILLPKNFPVNIYDLSVYGRANLIPILTAAANKFKIKI-EGP----TAMEGNREELE--
---------------GLF--GMVGSGV--------QLM-PGRLRKDALKKAETYMLHREPDGTLYSYFSCTFIFALMSLYDREH--PVITKAVQGLINMA
AVTPEGLHMQYT-TAHVWNTSLLSYALQEAGVS---GSIIQKANRYLRSKQHI--QYGDWVINPKAAPGGWGFSDINTMNPDIDDTTASLRAIKIEA-AE
---NF--QSREAWNKGLQWLLSMQNGDGGWASFERNAAPPY---VHPIEKAEFIISDESSADLTGRTIEFLCTFANL----N--PENSAVQKGIRWILKH
QETDGSWNSRWGICYIYGTWAAVTGLAAAGYSED-SPPIQRAKQWLEQHQNSDGGWGESCKSDIMYVPLG--TSTLTQTAWAIEALLCCSKI---TPSVE
RGIRYLISHI-RKTDWTSYYPKGGFAGQFYIHYESYDFVYPLLALSRFIKRANEG--
>tr|E6TY67|E6TY67_BACCJ Squalene/oxidosqualene cyclase OS=Bacillus cellulosilyticus (strain ATCC 21833 / DSM 2522 / FERM P-1141 / JCM 9156 / N-4) GN=Bc
---------------------------------------------------------------------------------------------LTNFQQQ
LIEDVRVKQLNDGQWKFPCESGPLTDAYMIVLLKLIDTRHE-H---LIKQLVDRLLYTQANNGAWKLYEDKDGNISATIEAYTALLFSRKIEHDE---RL
VKAKRFIYRNGGLKAAHVSTKFFLALNDLYPWPTIFPLPTWLLFMPSHIPISFHNMTSYVKIHFASVFILASKQFSIRT-PNP----DDLIMESKVKR--
-----------------L--KKQRNGK--------K-R-FSRINNAANLRAEKYILEREADGTAGSYATATCIYSLLALYRSDS--PIIRHAIHGLQKLT
VQINGKTHMENA-ESVVWDTSLLLYVLQESGFAI-EDEHVKKGGEFILRQQQK--T---------NENGAWGFSQNNSFYPDVDDTQACLRALQSLA-DK
---DS--TYRECWYNGLKWLLNMQNKDGGWASFNKNRRNHF---VKPIENISDTAIDISTADLTGRVVQFLGNNVKM----T--INHPKIKKAVQWLLKN
QEKDGSWYGRWGVCYIYGTWAAVTGLLSVGVSEN-DPAIQKAKKWLLSIQNKDGGWGESCSSDVHYVPLS--WSTPSQTAWALDTLIAICDP---NETIR
RGIEHLME-----RKGNFTYPTGGLPGNFYLTYHSYNSIWPLLAIAHFRKKYMK---
>tr|K0RJ27|K0RJ27_THAOC Uncharacterized protein OS=Thalassiosira oceanica GN=THAOC_28460 PE=4 SV=1
--------------------------------------------------------------------------------------TVPKPTCAIDAAKR
GVAFYSMLQTTDGHWAGDYGGPHFLLPGLVVAWYILGRPSNMISAEHGALMLHYLRVHQQEDGGWGTHIESPSTMFGTTMIYLAVRLLGGNKHD---EWV
KRGREFIKNEGGAIMTSSWAKFWLCLVGCMDWKGHNSVPPEMWLLPNWFPFHPGRLWCHCRMVYLPMGYLYGYRFVAETDPLIAELREELYCEHYDSIQW
ESTRHLVAEMDNYSPIPAFMIFAQNILSLYEN-WSIFRPFRDVRKKGLTFCAEYMKAEDQQTNFIDIGPVNKALNLVAAFASDVNHQAVQSHIMRVPDYL
WVAEDGMKAQGYNGSQCWDTSFAIQAIWECKLLDHFPLLSSKVWAYLERSQILSTPTSRERFYRHVSKGGWPFSTSAHGWPISDCTGEGLKGVLALMDSP
VAAVGKSIEPSRIHDAVNVMLTLQNEDGGWATYENNRGFGWYEELNPSEVFGDIMIDYSYVECSMASLTALAEFHEKFPCHRSDEIKLSICRGKEFMKSI
QREDGSWYGSWACCFCYGCWFGIEGLTKAGESHSS-ATIRKCCQFLLSKQRPNGGWGEDFTSCYDYARKGDEGSGVVSTAWALLALSAAKCDDV--NAVR
RGVQYLIDRQLDCGDWPQEGISGVFNRACGITYTAYRNVFPIWALGRCSSVY-----
>tr|V8NR84|V8NR84_OPHHA Lanosterol synthase (Fragment) OS=Ophiophagus hannah GN=LSS PE=4 SV=1
-------------------VEGRQKWYYVPENE-ECAREQNALEAYTL------------------GLNTSKFFPELP-----------KASTAQEAVLK
AIQFFSGVQAEDGHWPAECSGVLTLQTGLLIACYVSKI---SLPEEIKKEILRYIRSRQLPEGGWGLHLREQPTIFGTALNYIAMRILGYGPDHP---DI
VRARISLHKKGGALGAPHLGKVWLAVMNVYSWEGMNAPFPEL-LLPTWVPGHPSTYWCHIRHILLATTYCQLNRLSAEEDELVQSLRQELYVEDYSSIDW
LAQKKYIYEADLQAPHTLVLDVLFALFNLYDRYHL-----TSLRKKATAEIYEQIKADDIFSNSTNSSPICKPFHVLISWVDGPNSAAFQEHVSRIYDYL
WLTDEGIIMKAG----------------IHN-DPEYNTCLKKA-----------------HSFLKCSQGGFPFSNRDNDWMVSDCTAEAMKALMLLEEKC
P-FIEDHVAPQRLFDGINVLLNMRNSDGGFSSYETRRGSWLLEAINCAETYADCMVDHTYIECTSSVMQGLKLFQKKFPDHRREEISDTIHKALQYCRNT
QKADGSWVGRWGVCFTYGTWFALEAFACLGYTYHN-----GACAWLVSKQMKDGGWGEEFESYKFYIQHT--MSQVHQTAWALLGLMA------------
---------------------------------------------------------
>tr|R9PC98|R9PC98_PSEHS Lanosterol synthase OS=Pseudozyma hubeiensis (strain SY62) GN=PHSY_006427 PE=4 SV=1
RWRLRVSDG------------GRHVWHYLRDDA------EAQAWPQSVEDKY------------WLGL-----STGLP--------NLSPAKTPLDAAKN
GLSFYRHLQSTDGHWAGEYGGPMFLLPGIIIGMYATKT---PIPEEWKIEVVRYLWNRADKDGGWGIHIEGCSTVFGTALNYTVLRLIGVSAEHP---MM
VKARATLHKLGGAAGIPSWGKLWLAILNCYEWEGMNPIPPELWLLPDWMPIHPWRWWIHTRMVYIPMGYLWGRKFKAQMDPLIASLREELYTQPYESIDW
PAQRGNVAAVDVFYPHTKTLKTLMAVVGAYDNCHI-----PPLRKAGIKRAYELLVLEDENTSYQCLGPVNKMLNYVARWVEGHDSHAMRMHREKLKDFM
WIGAEGMMMTGTNGSQLWDTSFIAQAMVDSGLAAENRQLTSKMLDWLDSCQIRDNPKH-FQTYRFATKGAWPFSTKEQGYVVSDCTGEGLKAVIMLQQNV
P-YLSRKVSAERMHDSIDLLLTMQNPGGGFASYETINGPALLELINPAEVFGDIMIEYSYPECTTSVVTALLKFTKID-EYRKEDIRKCVDAAVKYILKA
QRRDGSWFGSWAICFTYATMFAVESLMLAGHTYENSEPIRRACAFLEEKQMDDGGWGETYK-----------------------------------DRIK
RAVRVIMDRQLADGSWAQEQIEGIFNRYVSTNNENQRE-------------------
>tr|Q0UAQ2|Q0UAQ2_PHANO Putative uncharacterized protein OS=Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) GN=SNOG_11162 PE=4 SV=1
-------------------------------------------------------------------------------------------KTPLEAASN
GLAFFSELQLEPGNWACEYGGPMFLLPGLVITWYVTET---PIPDDHATEIKRYLFNRQHPDGGWGLHIEGESTVFGTAMNYTVMRILGVDAEDP---RM
QKARATLWKLGGALKGPHWAKFWLSVLGVLDWDVVNPVPPELWLLPDWVPIAPWRWWIHMRMVFLPMSFIYSKRWTFPLTDLTRELRKELLTQPFETIEM
SAHRNDIAHTDNYHPKTWYLRLLWFVVAIWS-PYL-RWK--GLVKRAEEHVWWLIQAEDKNTDYSNLGPVNGPMNTLCCYVGGKEYEPFQEHLKTLPEFL
WMKDEGMLMNGTNGVQSWDTSFVIQAAESCGFVDRWKPMLTKALEFLEDQQILEEVPDQHKCYRQQRKGAWGFSTRKQGYTVSDCTSEGIKSALILQNAH
KY--PALIPERRLKDAIDVCLTMQNASGGCASYEPTRGSILLEHLNAAEVFGNIMIEYDYPECTTAVVTALHMFQKYYPSYRADEIAAFKDRAVAYIRHA
QRPDGSWYGSWGICFTYAAMFALESLACVGETYANSERVRRACEYFVDKQMDDGGWGETYKSCESWSQHP--QSQVVQTAWVVIAMIEGGYGDEQKEVLR
RAVRLIVQRQQANGEWLQEAIEGVFNKSCMISYPNYKFIFPIKALEQ----------
>tr|A0A0C9MNV4|A0A0C9MNV4_9FUNG DNA, scaffold: scf_mam1_v10046, strain NBRC 6742, whole genome shotgun sequence OS=Mucor ambiguus GN=MAM1_0046d03153 PE=4 SV=1
-WRLKVDE-------------GRQTWHYLT---TDEQRKA---WPQTIWDKY---------------------SLGLP--IDVP--DLPTPTTPLESARN
GFEFYRRLQTEDGHWSGEYGGPMFLIPGLIITHYITGT---PIPEAMRLELIRYLLNRAEKDGGWGIHIEGVSTVFGTALNYVALRIMGLGPDHP---AM
VKARGTLHKLGGASAIPAWGKFWLAALGVYDWKGVNPIPPELWALPKALPICPGNWWVHTRLVYLPMGYIYARRLSAPLTTFTQSLREELYIEPYDSIHW
DSQRNNVAKIDLYTPHSKIMDVLNYGLTYYES-LATKLP--QFRNYALKLTLDQIKMEDENSCFQTIGPVSKAMNWLVSFYEGRESREFKMHVEKNADFM
WMGPEGMMMNGTNGSQLWDAAFIAQACVEAKLAPEYRQNMVRLLEFIDITQIRRDPPN-GDKYRQSTLGAWPFSTREQNYTVSDCTAEGLKATIALQTTP
GPT---LVDLARLRQAVDVMLTMQNADDGFASYETIRGPHLLEKLNPAEVFGNIMTEYSYPECTTAVLMALRSFIKVDPEYRRAEIDETCRRSLLYIKRV
QHEDGSWYGAWAICYTYAAMFALQSLASVNEYYDTSDHAKRGCDFLVKHQEADGGWGESYKSCELHVYSRNEKSQVVNTAFAVRGLLEARYPDK--EPIR
RGIEFIMKRQQTNGEWLQESIEGVFNKNCMISYPNYKFSFTIWALGQYASVYGD---
>tr|V8P812|V8P812_OPHHA Lanosterol synthase (Fragment) OS=Ophiophagus hannah GN=LSS PE=4 SV=1
-----------------------------------------------------------------------------------------TACTAEEAALN
GMKFFSVLQAEDGHWAEDYGGPLFLLPGLLIVCHVAKV---PIPEASKKEMVRYLRSVQLPDGGWGLHIEDLSKVFSTALNYTAMRILGVSADDP---DL
VKARNNLHSKGGALGVASWGKFWLAVLNVYSWEGMNTLLPEM-LFPSWMPANPSTLWCHCRQVYLPMAYCYGVRLTAEEDELILSLRQELYVQDYDSIDW
PAQKNNTASGDLYTPHSWLLKVIYAITNIYEQ-FH----SKKLRQRAVEELYDHIKADDLFTKFISIGPISKMINMLVRWVEGEKSPAFQGHISRISDYL
WLGLDGMKMQGTNGSQVWDTAFAVQAFLEAGAQPEFDSCLILAHQHLRIAQIPDNPPNYEKYYRQMNKGGFPFSTRDCGWIVADCTAEGLKSVILLQEKC
P-FIKEHIPPSRLFDAVNVLLNMQNADG------------------------DIMVDYTYVECTSAVMQALKLFHKCFPEHRALEIREILQKGLRYCQKK
QRADGSWEGSWGVCFTYGTWFGLEAHACMQQAYCDCQAVSRACEFLVSKQMEDGGWGEDFESCEQYVQST--ASQIHNTCWALLGLMAA-----------
-------------------------------SYSSYRNVFPIWTLGRFSSLYPAS--
>tr|A0A0D9MA90|A0A0D9MA90_9EURO Prenyltransferasesqualene oxidase OS=Penicillium solitum GN=U727_0043184021 PE=4 SV=1
-----------------------------------------------------------------------------------------PATSPLESVSN
CLTFFSKQQLPPGNWGCEYGGPMFLLPGVVIAWVVTDT---HIPPVYAAEIINYLVSHANPDGGWGLHTEGDSTVFGTSLNYTVLRLLGVEAEHP---VM
IQARRLLHHLGGVLNAPHWSKFWLAVLGVCDWEIVNPVPPEAWLLPDWVPLAPWRWWVHIRQVFLPMSWIWSKKWTAPETDVIRALRRELFVQPWESIDW
AAHRNDIAPSDNYHPKTWLLNSINVFLADIWTPYLRPKS---LASRAEDWVSKLLDMEDANSDYADLASVNAPMNLLVCYRNGPDSYSVRRHRERMEEFL
WVNKEGMFVNGTNGVQCWDTAFLIQAVSAAGLAEDWRSMLTRGLEFLDRQQIRENCKN-QGVYRHFRKGAWAFSNRDQGYGVSDCISEALKAVILLQKEA
D-GYPQLLEDERIFDAVDTLLTYQNSSGGCASYEPTRGSEYLEMLNTAEVFGRIMIEYDYPECTSAVLTALTLFLKYWPGYRRTEIQAFIQRGVNYIKKA
QRPDGSWYGSWGVCFTYGTMFGLECLGSVGENYANSISVRKGCEFLLSKQREDGGWTESFQSCEQYIEHPT-GSQVVQTAFAIIALLSVDYPNS--EPIA
HGIRLIMSRQQANGEWLQEGIEGIFNKSCAISYPNYKFIFTTLALGKFAKKYPN---
>tr|Q4WA75|Q4WA75_ASPFU Squalene-hopene-cyclase, putative OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) GN=AFUA_7G00
-------------------------------------------------------------------------------------------------LQL
ATQYSKVQRRPGGNWRGQTGINSATTAEHIFMHQALGSN----LDTDRDAFISWFYSVQNSDGSWGISPGDRGDLSVTVEAYLALRILGVSRNVH---QM
RRSQSFILAEGSIANVCFITRIHLAMFGLYPWNAVRSLPPELVLLPQYILSSICCWPAVDLTVLIPLLILCHHRPI---FPLPI---QDCAASSYLHLQC
KPQ----EPQFCAFPPAPASTSTDLIVHLLNL--LK--YILPLRRYALDRSVAFILQTVRE--MGGVGPLSRPLHMAIVALEGYSSRSLRTTLDNIGHFV
YEDGGGKRVLSV-NTTFRDSSRMITGLQDAGIA-VNAPWFRTSVQWLQRCLLPDVNSD-TSK---------TFETRVCHVDDVASAIHAVI-----RQDP
LMLR-----SHLVANALQWLLKRQNADGGWTSLSSSHYRTS----------PDKLVRQSTPDVTGHVLETFGLLLTVSRRDTRDQVASASRRAIHYLSAT
QQPCGAWFGCCTRYHIYATSAVLRALAYFIGDSIN-DDVSQAIHWLESARNRDGGWGDICWRE------KGGPSTASQTALALLALLPYLSPID--SILR
DGVKYLLRTQTKGAIWTEDQPTRCSPACTSSSYS--SHCFVMMAIGSFRVSKG----
>tr|K2AK83|K2AK83_9BACT Uncharacterized protein OS=uncultured bacterium GN=ACD_62C00607G0008 PE=4 SV=1
-------------------------------------------------------------------------------------------------ITL
AQNNLINQGHKDGYWWYTLEANDSINAEYIMLLKYLEID----DKQTEKAICRWILHNQNHDGSWSLYYGAPGDLSATVECYIALKMAGFDSNQP---RM
AQARKFIMQLGGVSKIRVFSRIHLALFGLVDWKICPTMPVALIQFPEWAPVNIYEFSSWARASIVPLLVIMDQKKTKKITGLSI---DELYV--------
DSQ----KKEKWIYPNSILFIKIDKALHVADT--LK---FKPLRKQSLKKCEDFIRSHLG-----VTEDIYPAMFYGVLASLGYNDTNIEKALMGLKSFQ
FQDSSAHRDYMVYISPVWDTAWAATTLLKSGFP-ADSPILLKTARWLISKQITDVVGD-WGIKNPGSPGGWSFEFINKYYPDVDDTIEVLTFL-HDVGLP
YHVL-----KRPIEKGVNWLLSMQCSNGGFAAFDKDNDLVL----------LNKCLDPPTVDITGRMIEFLIKVLDFDGSHEA------VLLAADFITER
QEKDGSFWARWGVNYIYGTWCALEGLCCLSRKKDE-LIISRAVHWLKSIQNTDGGFCESSASY------NLGRSVPSQTAWALMGLVAAGQQFS--PEAR
KAADFLISAQKEQGGWDEKYYTGGFPGHFYIRYHGYRYYFPLLALSKYRDAIV----
>tr|A0A017S363|A0A017S363_9EURO Squalene cyclase OS=Aspergillus ruber CBS 135680 GN=EURHEDRAFT_533682 PE=4 SV=1
-------------------------------------------------------------------------------------------ADVSRCLQQ
AANYTKELVREDGHWCGEVKSNVSITAEYITLHHALGL---QVPE--PESWISWILSEQNQDGSWGLAPDMPGYVSFSVEAYFALKLLGVSPQHP---AM
VKANKSILAAGGVAQVRIFTRLFLAIFGLVPWAAVPELPPELILLPPSVLLSVYNMSAWARLTVVPLLLVSHHRPIFALPNGRSEYLDELWCAPYAPSLW
KPWR---M--DF---VTLVCTLTDGALHAVNG--MRNFPC---RSYARKQCLDHQEEDGSW-----AGYYPPMHASIIALLEGYKSRPVQRGLEGLQRFI
WSDQTGQRMQAC-VSPVWDTILMTIGLLDSGLP-RNSKYVLQSTKWLKDRQI-LGPQGDWKVNPKLRPGGFSFEYCNVWTPDVDDTAAAVL---AFVKQD
PQSVG----SEAVLRAIEWILGMQNNDGGWGAFDRENNKLFLNRIPFSD--MEAMCDPSEADVTARILEAFGLVMKFDSHTKPYDMRLSADCAMQFLANK
QETTGAWFGRWGVNFIYGTSNVVCGLAEYKSDARIGDWIQKGVDWLISIQNQDGGWGESLETYRDSTAGQG-PSTPSQTAWALMALLTSLPPTH--PAIT
GGVHHLLQTQVSAGSWPERSFTGI---------------------------------
>tr|A0A0D9MWV4|A0A0D9MWV4_ASPFL Prenyltransferase-like protein OS=Aspergillus flavus AF70 GN=P034_05557633 PE=4 SV=1
-------------------------------------------------------------------------------------------HEAGLTLQR
SMDYAYNVVRSDGHWCGEMSSNVTITAEYIFLRQALGL---DLKTD-GAAYCRHILSQQNSDGSWGLAPEYPGDVSTTTEAYLALKMLGLSTDAP---AM
QQAKAFVLNAGGVAKVRVFTRIFLATFGLFPWKAVPQLPVELILLPSACPINIYKFASWARGTIAPLLIICHHQPVYALPNGVFAYLDELWQEPYSPSIW
ELLSQ--G--DI---TGLTFSLLDKLLYQLNG--LRSIPLL--RSYALKQCMKRQEPTGDW-----AGIFPPMHASVYAFLEGYEDPPVRLGIEALENFA
WEDAKGKRVQPC-VSPVWDTTLMSIALSDAAAP-N-HQIVDRAIQWIRDRQL-LEPRGDWRVRPRLAPGGFSFEYTNSHYPDIDDSAAIIL---AQVKHD
PISAN----SSSVIAAATWILGMQNPDGGWAAFDVENDKLFLNKIPFSD--MDSLCDTSCADITGRILEAFGLLIRRVPDKDSSQIRAACRRGIRYLAST
QEANGAWFGRWGCNYIYGTSHALCGLAYFLQDQQVPAMVQPALQWLKSQQNDDGGWGESLLSYQSERKEQR--STASQTAWALMGLLAHLPHTD--IVIE
RGIRWLVSSQRPVETWPEPVYTGT---------------------------------
>tr|A0A0A2IL23|A0A0A2IL23_PENEN Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid OS=Penicillium expansum GN=PEX1_031740 PE=4 SV=1
-------------------------------------------------------------------------------------------SQVEHALKL
SRDYANGSVHSDGHWCGELRSNVTITAEYIFLRQALGL---DMKAD-SAAYCRHILSEQNEDGSWGLAPEHPGDVSTTTEAYMALKILGLDSSHV---VM
RRARQFVLKSGGIEKVRVFTRIFLATFGLFPWDGVPQLPVELILLPSICLINIYTFASWARGTIAPLLLICHHQPIFPLPNGKFAYLDELWLVSYGLPLL
SLLFE--G--DL---PGVAFTCMDKLLYWLNG--LRSVPVL--RSYARRKCLKRQEVTGDW-----AGIFPPMHGSVFAFLEGYNDDPVRLGIQAIENFA
WEDERGKRIQAC-ISPVWDTALMSIALSDAMTP-D-RHVVEQAITWIRNRQL-IVPYGDWCVRPGLPPGGFSFEYKNTWYPDVDDTAAVIL---AQIKHD
VESIG----SDSVIAAAMWIVGMQNPDGGWAAFDVENDKLFLNKIPFSD--MDSLCDTSCADITGRILEAFGLMMKRAPEKSLADLRAACTRGIRYLAST
QEPSGAWFGRWGCNYVYGTSHALCGLAYFD-DTRVSGLVLRGIQWLGSKQQADGGWGESLLSYRSSQDWQG--STPSQTAWALMGLLAHLSPKD--LAIQ
RGIQYLVATLQPEKSWPQSVFTGT---------------------------------
>tr|A0A084IK69|A0A084IK69_9GAMM Terpene synthase/squalene cyclase OS=Salinisphaera hydrothermalis C41B8 GN=C41B8_11653 PE=4 SV=1
--------------------------------------------------------------------------------------------GLAEAIDA
AQTRLFADQNPDGHWRYECEADCTIPAEYILMMHFVGDVDTA----LQARVANYIRYKQAAHGGWPLYYGGDLDLSCSVKCYYALKLAGDDVDAP---HM
VHARQAILARGGAGQVNVFTLIALAQFGQVPWRAVPFIPVEVMLMPQASPFHLSKVSYWSRTVMVPLFILTSLRTMARN-PAGVNI-RELFTIPPEQRDF
VPAQN------------TLQRVFK-GLDRSFEPLI----PKFVRKRAIKTAENWIIERNGTDGIGAIFPAMVVYEALGEYPADH--PYRANTRQAIDDLV
FDHGDMANVQPC-VSPVWDTGLAALALQEAAGE-GDTPVVRAGLDWLAERQVLD-GPGDWKRHPDLPGGGWPFQYANDHYPDLDDTAVIAWAMYNTG---
---DG-ATYGRAITRATNWLVGMQSSNGGVAAFDSDNNHEY---LNPFADHGAL-LDPPTADVTARVLTLTGLLQR-------PEDGPFIQRAMAYLKRE
QEADGSWFGRWGTNYIYGTWSVLMALEALGEDMS-QDWIQRAVAYLRGMQRTDGSWGEDNGTYWDPRGRS-DVSTSFQTAWAMLGLMAAGE--RDTPALA
RGAAWLIDAQGDDGAWHDPEHTAGFPRVFYLKYHGYTRYFPLWALARYRNVHGV---
>tr|U1GM21|U1GM21_ENDPU Uncharacterized protein OS=Endocarpon pusillum (strain Z07020 / HMAS-L-300199) GN=EPUS_05037 PE=4 SV=1
-------------------------------------------------------------------------------------------EEALNTLQQ
AIEYSFEKQKSDGHWTEECVADVTFTCQYVMFK--------------------------RPERGWLLVSGPVGNASTTTEAYLALKILNVPADHP---SM
LKASAWVRKAGGVEK----------------------MPAELILMPPSFFLNIYTLSSWARSTLIPCLIIRHHDPVYAL-PNRSAFLDELWSNPRNNIPF
ASPLSMLWKGD-YIEYGF--TLFDNILGL-----LGGLKHSPNRGLARKKCVDWLIEHEVQGDWAGFFPPMHPWALIEEYPFDH--KAVVLGLDALERLS
TTDTRGKRLAPT-ISPLWDTALMIGAMCDAGVG--RDARVQKAINYVKERQLLG-PEGDWRISRNQQPGGWSFEYFNTWYPDVDDTAVVVMSLIKQDPY-
------FIESERISNAVTWMLGMHNRDGGFAAFDVDNDKLGLHKI-PFSDMDSL-CDPSTADVTGRVLECFGLLLSHRKGSRQLRVQLASERAIEFLLAK
QEPFGGWWGRWGNNYNYGTSNVLRGLVHFAQDSAVQHMVDRATRWFESVQNSDGGWGETLVTYERLAGTG--ESTPAQTAWGVTALLPYRPAS--YPAIE
RGIRWLIANQTDKATWNQDVYPGGFPMVLYLNYPYYHHYFPITALAKYLDGT-----
>tr|M5U8T9|M5U8T9_9PLAN Squalene-hopene cyclase OS=Rhodopirellula sallentina SM41 GN=RSSM_00880 PE=4 SV=1
---------------------------------------------TVHSDNQSLAAGSSDQVVRNQGFRDQAFRD-----------------QVRRTLDD
LRDQLLAERADRSHWIGELSASALSTATAISALSVACELKDGEQLDLIRRGVTWLQSQQNDDGGFGDTNRSHSNIATSYLVLAAHTILPENTDAPSDTQD
ERLRRYLDDAGGLDALKRYGKNNLAIAGLVPWSEVAALPFEAAVFPQSM----YR--------YLGMPVVS-----YAV-PALV------------AIGQ
AFYRSG-------------------CL----------PPLSWIRQASLNPTLALLERMPDSGGYLEATPLTSVMSLVDSLQLNPKSRVIETGLNFIEQ--
SITPEGSWPIDT-NLATWVTSLSIAALTSDPNDREW--SGVELVDWLLSCQHTERHP-----FTGADPGGWGWTDLSGAVPDADDTPGAILALLKLRNYV
DEQRG--RIDQAISHGRDWLLGLQNRDGGWPTFCRGWGKLP--------------FDRSSVDLTAHAIRALDDLSDS------PKVDAAITVGLAFLRKQ
QRPDGSWVPLWFGNPIYGTAKVLVD---VHPRLD-KTAVVRGIEYLINHQNADGGWGGSVESDTDQKPSDFGVSTVEETALAVEALASLWVPDRTRDAIL
SGSRWLMRAA-RGGRLDVAWPIGFYFAKLWYHERLYPLIFTTAALGRVA--------