>seq_1
MPDFRSILDDDRIYYFDGGYGTLLQSRGLPAGLSPELWGLKEPDVIRAVHRDYIEAGADILTTNTFGGSRPKLGLGVDPFELNRAMTAIAREVAGDRAFV
AASIGPTGHFVKPLGEMTFRELVDIFKEQIRGCVAGGADLILGETHFDLAEAKAVVVAARLVCDLPVAISMTFEGEASLTGTSPMTFVDTMQNMGVELIG
TNCSAGPEQMRDTLRAWAPRLSTPTFAEANAGLPELNAEGKTVFRLQPEPFAEKAAAFVELGAKFIGGCCGTTPEHIRALRDKVGDARWQRPVRTDNAQL
VLTSRSVSVPVGFDHRGVIIGERINPTGKKQLTAELQESVFSEALRLAAEQAELGAPVLDVNVGAPLVDEAALLPELVTALLGRVTTPLAIDSNDPAAVE
AGLWAYPGSPLVNSISGEPGKMERLGPLCKLFGAPFILLPIVGRKLPVTAAERLKVIEDLLAQADALGIPRRLILVDALALTVSSKPEAARHSMEVMRQC
RDRWGLPTTIGLSNISFGLPARELLNSTFLSLSMASGLCSFIGNPNSARIRETLHAAEVLLDRDPQAARYIDNFSGWVGGGGVQAATSQAAPSGAASLPP
VQAAVVKGDKDNVVRLVEAELDKGMAAMEIVNDLLIPGILIVGDKYETKEYFLPQLLQSAETMQTAFQRLKPLLEEAGGAGARPVVVMATVEGDIHDIGK
NIVCLMLKNYGFDVVDLGKDVPAEKIVAAAEEHDAALIGLSALMTTTMVRMEDTVKLVAERNLRAKVIIGGAVVTEKFCKAIGAHGWSTDAVAAVKLAQR
LTQ
>tr|B8DKK4|B8DKK4_DESVM Homocysteine S-methyltransferase OX=883 OS=Desulfovibrio vulgaris (strain Miyazaki F / DSM 19637). GN= PE=4 SV=1
MPDFRQALRSGRRLVFDGGMGTMLQSRGLPPGVSPELFCLARPDVLVGIHADYLRAGADVLTTNTFGGCIHKLGTGPDVVEFNRAMARAAREAVGREAFV
AGSVGPSGHFMRPLGDLDPAELVAAFRAQIRGLVQGGVDLILAETQFDLAEARAIVLAARAECDLPVGVSMTFENGVSLTGTRPEVFVQSMLNMGVDLVG
TNCSAGPEQMAEVADELLAISEVPVLVEPNAGLPEL-VDGKTVFRLGPDDFARHTARFAASGVRMLGGCCGTTPDHIAALRGALDNLSGGLVPDPARDGI
VLTTRAQAVHIGAGSPIRIIGERINPTGKKLLTAELQAGEFAQALRFADEQVEAGAPLLDVNVGAPMVDEAVLLPALVERLVARHSLPLSLDSSNADAIA
AALPFHPGSPLVNSISGEPGRMEHLGPLCRDHGAPFILLPLKGRKLPVTAAERIAIIEELLQQADSLRIPRRLVMVDVLALAVSSKAEAARHCLDTIRWC
AAQ-GLPTTIGLSNISFGLPARELLNSTFLAMAAGAGLSSCIAHPGNARIREAVAASSVLLGLDANAESFIEGYSGWTPV-----AGGTGGGTGKAKAAT
LEEAVIRGDREGALALVERALSEGADPFSLVQEKLIPGITEVGRRYERREYFLPQLIRSAETMQHAFRKLQPLLEAQRGHEARPVIIMATVEGDIHDIGK
NIVTLMLGNHGFDVVDLGKDVKAADIVEAAERHGARVIGLSALMTTTMVRMEDTVRLVRERGLPVKVMVGGAVVTPAYAEAIGADGYSADAVEAVRVAKE
LLT
>tr|I5AXY2|I5AXY2_9DELT Homocysteine S-methyltransferase OX=879212 OS=Desulfobacter postgatei 2ac9. GN=DespoDRAFT_00042 PE=4 SV=1
MGEKDLDIINKRILILDGATGTEMQKRGLPPGVSPELWSMENPEVSADIYRAYARAGSDMLYTCTFGGTPWKLEEGADKTEIAQNAVKVASEREGIRPLI
VGDIGPCGRFIMPFGDLDFEQAVLGFKRQVRGLIDGGVDLFVIETQIDIQESRAALLAVKEICGGFTMVSMTFDTGHSLNGTTPEAMAVTLESLGADVVG
VNCSTGPKEMLDIIRRIRKMVQIPVMAKPNAGMPVI-KDNETVFPMAADEFSTFAKPFAEAGVNIMGGCCGTTPTHIAKLAQSMEGLVPLERKPVETAM-
-LSSATQALITGSNSTIRIIGERINPTGKKILQGELKAGNMAYVRNLARDQAAAGADLLDINAGMPGIDEKQTLLDIISSVVPVVSLPLVIDSSDPDVVE
AAVRYYPGRALINSISAEKEKLERLLPVAAKYGAMFIVLPLADNELPDKAERRKELVMEIAERAAAYGYKNKDLVVDGLVMTVSSNPQAAKETLATVRWA
SQQ-GFGTVLGLSNISFGLPERGWVNASFFAMAAGAGLSWAIANPSHELLMDTKAASDVLTGRDRDALSYIQRFAKDKNT-----TA-KKKTD-LPVEDQ
IVEAVIEGRREDIERLCNQALEMGIAPSELLEKKMIPAIMTVGEYYDARKYFLPQLIASAETMQNGFAVLEPALQASGSNKKKGTLVFATVQGDIHDIGK
NIVVLMLRNFGFDVIDLGKDVTAEKIVAAAQTHKADLIGLSALMTTTMVRMPEVIALAKENGLGCKVMVGGAVVTREWAESIGAE-YSSDGVEAVNVAAR
ICM
>tr|Q2LWJ5|Q2LWJ5_SYNAS 5-methyltetrahydrofolate--homocysteine methyltransferase OX=56780 OS=Syntrophus aciditrophicus (strain SB). GN= PE=4 SV=1
MKSKERRLLKKKILVLDGATGTELQKRGMPGGVCPELWCLEHPEIIKEIHRSYRQAGSDIVYTCTFGANRYKLAQGTEVREINRNLARLARHAVGPKALV
AGDIGPTGHFVEPFGDLPFEEAVSAFKEQIQGLLEGGVDLFVIETMMDIQEARAALIAVKETCPAFTVVTLTYEGGRTLNGTDPATALITLQSLGADAVG
CNCSTGPEAMLAFIEAMKPHATVPLAAKPNAGLPRL-EGEETFFDMDAETFASHGPAFAAAGVNLLGGCCGTTPDHIQALAGTLQNAPP--RPPVRAALS
AVSSARSYRLLTRNEPLVIVGERLNPTGKKALQQELLAGKMSLVRQMTREQEQQKADLLDVNVGVPGLDEVKTIREVISLLATATELPLVIDSSKVETIE
TALRLYPGRALINSISGEKKKCERLLPLAARYGAMFILLPLADGEVPETADRRIAIVREVYGKARRLGFTKEDIVVDGLVMTAATNANAPAETLKTIAWC
TDRFQAKTILGISNVSFGLPERKWLNAAFLAMAQLSGLTMAIANPSMEELMALKRAADVLTARDAQASAYIAHFAGTAET-----SAMQPPAP-AGPEEK
VRAAVLEGNRDDIGDLVEGALSAGFEARSIVDDLLIPAIVQVGELFDRKVYFLPQLIASAETMKKALAILEPRLKSGGPEKARGTVVMATVQGDIHDIGK
NIVVLMLKNHGFRVLDLGKDVPVETILETIRTENPDVVGLSALMTTTMVSMKTTIEQARSADLTCPFLIGGAVVTRSYADSIGAA-YARDGVEAVRVVEQ
LIG
>tr|E8WMU3|E8WMU3_GEOS8 Homocysteine S-methyltransferase OX=443143 OS=Geobacter sp. (strain M18). GN= PE=4 SV=1
MMPFMQAVKE-RVLVLDGAMGTMLQERGLKAGQSPEEMNLTAPEVVAGVHRAYLEAGADIIVTNTFGGTKAKLEHGLDQVTINAEAVRIAREVAGESAYV
AGSIGPTGRFVEPVGDMSFDEACALFGEQAKALIDAGCDVISLETFLDIKEIRAALIAIRELSDIPVIAMLTFEKGRSVLGSPPEAAAITLEAAGASMVG
SNCGLGVDGIYDILCAMRKVTSLPLISQANAGLPIL-KDGVTVFPGTPDEMTAYHDRMIGLGVRVIGGCCGTTPVHISAIKAALSGRQTPFTPKEDDGTT
WISSRGSFAPIGALHPVALIGERINPTGKKLYSQELREGKVSYIRREALEQTELGATLLDVNVGTPGIDEPAAMERAVFCVTGAVQTPLVLDSSSPQALE
AGLKAADGKVLINSVNGEEKSLAAVLPLAKKYGAALVCLTLDESGIPAEAEGRVAVAQTIAGHAAAAGIKRSDLVVDCLTLTVSAEPKGALTALEAVRRV
TE-LGLNTTLGVSNISFGLPCRPLISSSFFSMAMAAGLTSAIVNVKEAPMMAAWRSSMVLLGKDVNAARYIEAYKGAAGS-----ATVEAAAEPEGIRGR
LSRAVINGELEAVVPLVEEALAEGLSPMQISSEALLAGLDEVGRRFGNGSFFLPQVMVSADTMKAAFARLKQELAGG-GLESLGKILMATVEGDIHDIGK
NILVTLLENNGFEVIDLGKNVPAARILEEARAHQVDAVGLSALMTTTMAQMDKVVSLLKSEGVKSFTMVGGAVVTQQYADEIGADLYAKDAMEAVARIKE
LLA
>tr|C6DY72|C6DY72_GEOSM Homocysteine S-methyltransferase OX=443144 OS=Geobacter sp. (strain M21). GN= PE=4 SV=1
MMSFMQAVKE-RVLVLDGAMGTMLQERGLKPGQSPEEMNLTAAEVVAGVHQAYLDAGADIIVTNTFGGTKAKLEHGLDQVAINAEAVRIAREVAGEKAYV
AGSIGPTGRFLEPVGDMSFDEAVSLFREQAQALVDAGCDLISFETFLDIKEIRAGVIAVREISEIPVIAMLTFEKGISVLGTPPQAAAITLEAVGATIVG
SNCGLGPDGIYQILSDMRDVTALPLISQANAGLPIL-KDGVTIFPATPDEMTAYHDRLIELGVRIIGGCCGTTPAHISAIKKALAAKQAPFAPKKEDGTT
WLSSRGSFAAVGAAHPVALIGERINPTGKKLYSQELREAKVSYIRREALEQAGLGATLLDVNVGTPGIDEPAAMERAVFCITGAVQTPLVLDSSSPEALE
AGLKAADGKVLVNSVNGEEKSLAAVLPLAKKYGAALVCLTLDEAGIPAEAAGRVAVAEKIAAAALAAGVKRSDLVVDCLTLTVSAEPKGALVALEAVRQV
SA-LSLNTTLGVSNISFGLPCRPLISSTFFSMAIAAGLTSAIVNVKEAPMMAAWRSSMVLLEKDVNAAGYIEAYKGQGAA-----VARAAAVEPEGVRGR
LSKAVINGEADNVVALVEEALSEGLTPMQISSEALLVGLDEVGRRFGSGEFFLPQVMVSADTMKTAFARLKMELSTG-GLQSIGKILMATVEGDIHDIGK
NILVTLLENNGFEVIDLGKNVPADRILYEARAHQVDAVGLSALMTTTMAQMDKVVKLLKAEGVKSFTMVGGAVVTQEYADEIGADLYAKDAMEAVARVKK
LLA
>tr|Q30ZI4|Q30ZI4_DESDG Methionine synthase OX=207559 OS=Desulfovibrio desulfuricans (strain G20). GN= PE=4 SV=1
MPDFRRALSDDTLLFFDGAMGTMLQGRGLPAGMSPEVFCLSNPAVLQGVHLDYARAGADVLTTNTFGGTRLKLPEGMNVVEFNREMARAAKAAAGRTVFV
AGSVGPTGHFVKPLGDLEFSELVDIFREQIRGLVQGGIDLVLAETHFDLAEVRAVVLAARAECNLPVGVSMTFEDGVSLTGTRPEVFVHTMQNMGVDLIA
TNCSAGPEQMAGVVAGLTAAGDIPVLVMPNAGLPEL-ENGNTVFRLGPEEFAAQTADFVRAGVRCLGGCCGTTPDHIAALAREARSKPRPAVEKRRRSGI
VLTTRAACLRIGHDQPCRIIGERINPTGKKELTAQLQAGDFTLAMQFAQQQIDAGAPLLDVNVGAPMVDEKVLLPQLISDLAAAHGVPLSIDSSDMDAVE
ASLAVYAGSPLVNSISGEPGRMERLGPLCRDYGAPFVLLPLKGRKLPVTAAERISIIDELLLQADDLGIPRRLVMVDVLALAVSSKAEAARHCFDTIRYC
NEELGLPTTIGLSNISFGLPARELLNATFLAMAVGAGLTSCIAHPGNVRLREALAAAEVLMARDSNAERFIAGYSGWTSI-----IAGGGEE--KKRPVS
LEEAVIRGERDIILELVEDELARGAQPYALVNERLIPAITEVGDKYERKEYYLPQLLRSAETMQKAFGRLKPLLEEASGGETKPVIIMATVEGDIHDIGK
NIVCLMLGNHGFDVVDLGKDVKAVDIVDAAVEHNAKLIGLSALMTTTMVRMEDTIQLLRERGLSIPVFVGGAVVTPAFAEAIGAAGYSRDAVEAVRIARG
LVE
>tr|B9M4J9|B9M4J9_GEOSF Homocysteine S-methyltransferase OX=316067 OS=Geobacter sp. (strain FRC-32). GN= PE=4 SV=1
MQPFLQSIKD-RVLVLDGAMGTMLQQRGLKAGQSPEELNLTLPEVVAGVHQEYLDAGADIIVTNTFGGSREKLSHGLGKLAINARGVEIARQVAGARAYV
AASMGPTGKFVEPVGDMTFDRMAAQFREQAEALVGAGADLITLETFLDIKEIRAAIIAIREVSEIPIIAMLTFDKGRTVLGTPPEAAAITLEAVGADIIG
SNCGLGVEGIYEILSAMRRVTSLPLISQANAGLPVL-KEGKTIFPATPDEMTAYHDRMLQLGVRIIGGCCGTTPAHIGAMKDALAGKNQSLPDASSGGTT
WLSSRGGHAALGNGRPVAIIGERINPTGKKAFAAELREGKVSYIRREAMEQVVAGATLLDVNVGAPGIDEPAAMEQAVFCAAGAASVPLVLDSSNPEALE
RGLKSADGKVLINSVNGEEKSLGRILPLAKKYGAAVIGLTLDENGIPETAEARTAIAAKIANRAVSLGIRRNDVIIDCLTLAVSAEQKRALETLEAIRRV
KGQLGLSTVLGVSNISFGLPCRPLISSAFFAMAMEAGLDAAIINPKEQAMMDVWRSVMVLLNRDANAATYIDAYKGVAAS-----AG-QVEAAPQDIRGI
LARAVIDGDVENIVVHVEAALAQGLSPLEISNNGLLPGLEEVGRRFEKNIVFLPQVMLSAETMKTAFSRLKQEMQGM-KLESSGRILMATVEGDIHDIGK
NIVCTLLENHGFEVIDLGKNVPAARIVAEAKAHDVDAVGLSALMTTTMSEMETVVQQLRTAGVKTFTMVGGAVLTQDYAIEIGADIYAKDAMEAVSKIKA
IIG
>tr|F2LVY3|F2LVY3_HIPMA Methionine synthase OX=760142 OS=Hippea maritima (strain ATCC 700847 / DSM 10411 / MH2). GN= PE=4 SV=1
MRNFREELGR-KILILDGAMGTQLQEKGLKTGSCPDYLNVTHPKEIGEIHKTYLDAGADIIVTNTFGANPIKLEENLDKVYINYEAVRIAKEVVKDKGFV
SLSIGPTGKFIEPVGEENFDYIKDIFKKQVRPAVDADVDLFSLETFMDIKELKAAIIAIREITDKPIIAMMTFADGRTILGTSPEVFAKTIEPMEVDVIG
ANCSVGPDLLNEFVKKMAQVTDKPLIIQPNAGIPRL-VNGKTIFPVGAEEFASYANDFKEYAA-IVAGCCGTGPEHIKLLAEKLKGKPVKKRT--IQKAT
VLTSRSQMVEIGYSRPVVFIGERLNPTGKKHLKEQLKEGKTGLYRKEAIEQVEHGAMVLDINVGVPMIDEPTTMKKCVLAVESVVSVPLVIDSSNIEALE
AGLKAADGKVLINSVNGSQESMEAILPLAKKYGAAILALLLDETGIPETAEDRLKILDKIVKNAKELGIKEEDIVADALALTIGSDKKRALETLRAIKLI
KEKYGITTILGLSNVSFGLPNRKLINSSFMAMAIYNGLDSAIVNPYDELLWQIKYASDLIVDRDKDSSIYINNSSDTTDN-----AKLELIKSPFDLEDK
LFMCVIEGNEEEIELLTKQALKNK-EPLKISNEILIPALDAVGKLYDKGIYFLPQMIKSANAMKKAFNILKEIIKKK-ATKQKTTIVMATVKGDIHDIGK
NIVSLLLETNGFEVVDLGKNVDDETILKAIEEYHADAVGLSALMTTTMINMKNVIDEIKMKGLNVKIMVGGAAVTEEFAKKIGADMYAKDAIEAVRLAKE
NV-
>tr|C6BTZ8|C6BTZ8_DESAD Homocysteine S-methyltransferase OX=526222 OS=VKM B-1763). GN= PE=4 SV=1
MPDFRKALSDDKIYFFDGGYGTFLQSRGLPAGMSPELFGLQSPEVIKSVHKDYVDAGANVLTTNTFGGSRPKLGADVDVIGLNREMALLARSVGGDNVFI
AGSVGPTGHFVQPLGEMTFKEMVEIYKEQITGLVEGGVDLILGETHFDLAEARAVVIAAREVCDLPVALSMTFESPSALTGTSPATFIDTMQNMGVELMG
TNCSAGPEQILEVLENMQPRLCSPLLVEANAGLPELDENRNTVFRLQPEPFAEQSAKFVDVGAKFIGGCCGTGPDHIRALRNKVDGAKWKRAVPQEDCQM
VLTSRSQSVKIGFEQRGVIIGERINPTGKKQLIAELQKGQFTEAMKFAEEQIAVGAPVLDVNVGAPMVNEVEILPALVKEIFAQHSAPLSIDSTNPDAVE
AALWEYPGSPLVNSISGEPGRMERLGPLCKKFGAPFILLPIVGSKLPITCAEKVEVVSELLKQADDLGIPRRLIMVDALALTVSSKPMAARHCLDFIKHC
KEEWNLPTVLGLSNISFGLPARELLNSSFLTLCQGQGMAAFISNPNSVRLREALYANEVMLCRDPQAEQYIERYADWTPG-----AAGGGKKADKSGAEN
LFDAVVKGDRGSIVALVERDLEGGREPFAMVNEDLIPAIMEVGEKYERKEYFLPQLLQSAETLQKGFEKIKPLLEASGDMEEKATIIMATVEGDIHDIGK
NIVCLMLKNHGYNVIDLGKDVPAETIVNAAEEHGAKIVGLSALMTTTMVRMEDTINLIKERNLDIKVMIGGAVITGGFCDSIGADGWSTDAVAAVKVAKN
LLQ
>tr|A1ANV9|A1ANV9_PELPD Methionine synthase (B12-dependent) OX=338966 OS=Pelobacter propionicus (strain DSM 2379). GN= PE=4 SV=1
MTPFLEAIQE-RVLILDGAMGTMLQERGLRPGQSPEELNLTMPDVVASVHREYIEAGADIIITNSFGGSRFKLAHGLGRLAINARAVEIARGEARGRAYV
GGSMGPTGQFVEPLGEVSFDRMKESFREQAEALVSAGVDLISLETFLDIKECRAAVIAIREVSTIPIIAMMTFDNGRSVLGTPPEAAAITLAAAGVDIVG
SNCGLGVEGIHDILVRMRRVTSLPLISQANAGLPIL-KDGITVFPGTPREMTDYHDRLISLGVRVIGGCCGTTPAHIRAMKEALAGRQQVWQETHLEGMT
LLSCRGGWTAVGPGQKTAIIGERINPTGKKLYSKELQEGKVSYIRREAMEQAQLGATLLDLNVGAPGIDEPVAMERAVFCASGAVGVPLVLDSSSPAALE
AGLKAADGKVLINSVSGEAKSLSRVLPLAKKYGAALIGLTLDAKGIPDSAEGRLAIARRIRNAARRQGIPDQDIIIDCLTLTVSAEQKRAAETLRTIRLV
KEKLGLSTVLGVSNISFGLPQRPLISSSFFSMAMAAGLDAAIINPREKAMMDAWRSAMVLLNRDPRAEAFIQTYRDAVAT-----PAAPVSDAPQEIRQR
LGQAVINGDRDGIIGLVEEALAQGLAPLQISNEGFLPGLEEVGRRFEKNIFFLPQVMQSADTMHAGFARLKEEMKGQ-PLESRGRILMATVEGDIHDIGK
NIVCTLLENHGFEVFDIGKNVSAATIVAKAREFGVDAVGLSALMTTTMAEMDTVLKKLKAVGIKAFTMIGGAVVTQEYADRIGADIYARDAMEAVAKVKK
LLQ
>tr|G7Q4K8|G7Q4K8_9DELT Methionine synthase OX=644968 OS=Desulfovibrio sp. FW1012B. GN=DFW101_1221 PE=4 SV=1
MGDFRQALGDGEILVFDGAMGTLLQGRGLAAGQSPELFGLAHPEAIVATHREYIEAGSRVITSNTFGGTRYKLPPGTDVTALSRDMARLARQAAGQGVFV
AGSVGPTGQFVAPLGKASLAELVAAFATQIKGLAEGGCDLIVGETHFDLAEAKALVLAARQVCSLPVAVCMTFEGAVSLTGSGPEVFADAMENLGVDLVG
VNCGAGPDDMRLVAEVFSRRLSTPFFVKPNAGMPRL-EGGRTVFPMGPEEFAEKTARFADLGAKALSGCCGTTPAHIKALAGALAGRTHTRPEAVDRPVL
AVTSRALTVTLGGKSPCAVIGERINPTGKAGLAAELAAGEFAQALAFAEEQVAAGAAILDVNVGAPMVDETVVLPGLAVELTKRQQTPLCLDSNNADALV
AALYASPATPLVNSISGEPGRMERLGPICRDHGAPFILLPLKGRKLPVTAAERLAIIEELLVQADGLGIPRRLILVDALALTVSSKPEAALACLETIRHC
RERWGLPTVLGLSNISFGLPARELVNAAFFAMCLGAGLSAAIANPNVPRLMETSGACEVLLARDPQAGRFIGRFAGWTPP-----TAASAGGAGEEGASP
LRQAVVRGRRAELDGLIDAALAEGRAAADILSEDLIPGIMDVGERYERKEFFLPQLLVAAEAMRAGFTRLEPLLAETAGAA-KARIVMATVEGDIHDIGK
NIVCLMLKNHGFEVIDLGKDVPAATIVAEAEARDADVIGLSALMTTTMVRMEDTVRLVRERGLRAKVMVGGAVVTEAFAKSIGAHARAADAVDAVRQAKA
LLG
>tr|L0RC92|L0RC92_9DELT Homocysteine S-methyltransferase OX=1121451 OS=Desulfovibrio hydrothermalis AM13 = DSM 14728. GN=DESAM_20894 PE=4 SV=1
MPDFRKALGDGRVYFFDGGYGTFLQSRGLPAGMSPEIFGLESPEVIRSVHQDYVDAGANVLTTNTFGGSRPKLGADVDVSGLNREMALIARSVAGDKVFV
GGSVGPTGHFVQPLGEMTFKELVEIFKEQVQGLVEGGVDLILGETHFDLAEARALVIATREVCDLPVAVSMTFESPAALTGTSPLTFIDTMQNMGVELMG
TNCSAGPEQIFEVLKNMQPRLSSPLLVEANAGLPELDENRNTVFRLQPQPFAEQSARFLEVGAKFIGGCCGTGPDHIRALRKAVGDATWKKPVPQDDCQV
VLTSRGQSVAIGFEQRGVIIGERINPTGKKVLIEELQKGQFTEAMKFAQEQITAGAPVLDVNVGAAMVDEVKTLPALTKEIFAQHSAPLSLDSTNPDAIE
AALWEYPGSPLVNSISGEPGRMERLGPLCKKFGAPFILLPIIGSKLPFTCEEKVEVVSRLLKQADDLGIPRRLIMVDALALTVSSKPVSARHCLDFIRYC
REEWNLPCVLGLSNISFGLPARELLNSTFLTLCQGQGMAAFIANPNSTRLREALYSAEVLLARDPQAEQYIDKFADWTPG-----GGGGTKEKDKTGAEN
LFDAVVKGERGSILDLVERDLEGGREPFALVNEDLIPAIMEVGEKYERKEYFLPQLLQSAETLQKAFGRLKPLLEAAGGTKEQDTIVMATVEGDIHDIGK
NIVCLMLRNHGFNVIDLGKDVSAEAVVDAAQENGAKIIGLSALMTTTMVKMEDTINLIKERGLDIKVMIGGAVITGGFSESIGADGWSTDAVSAVKIAKE
LLQ
>tr|K6GMS1|K6GMS1_9DELT Homocysteine S-methyltransferase OX=1206767 OS=Desulfovibrio magneticus str. Maddingley MBC34. GN=B193_3046 PE=4 SV=1
MGDFRKALADDALLLFDGAMGTLLQGRGLSAGQSPELFGLTNPDAIIGAHRDYVQAGSRVITTNTFGGSRYKLPAGTDVVGLNREMARLARQAAGPGVFV
AGSVGPTGHFVAPLGKASLRDLVDAFAEQIRGLAEGGCDLIIGETHFDLAEAKAVILACRQVCSLPVAMCMTFEGAASLTGSGPEVFADAMENLGVDLIG
VNCGQGPDDMRLVGEAFSRRLKTPFFVKPNAGMPRL-ENGRTVFPMGPDEFAEKTARFVDLGAKALSGCCGTTPAHIAALGVALAPRSWKRADTPDRPVL
AVTSRAMVVPIGGGAPLAVIGERINPTGKAELAAELVAGEFAKALHFAEEQTAAGAHILDVNVGAPMVDETAVLPGLALELVKRQQLPLCLDSNNIDALT
AGLWAYPGTPLVNSISGEPGRMERLGPICRDHGAPFILLPLKGRKLPVSAAERLAIIEELLLQAEGLGIPRRLILVDALALTVSSKPEAALACLEVIRTC
RDKWGLPTVLGLSNISFGLPARELVNSAFFAMCLGAGMAAAIANPNVPRLMETLAAGEVLMGRDPQAGRYIAGYAGWKPT-----ASGPASGGADDGESP
LRRAVVYGRREEVLERIEKALAEGADAATLLGEELIPGIMSVGERYERKEFYLPQLLAAAEAMRAGFTRLEPLLTEAGETA-KARIVMATVEGDIHDIGK
NIVCLMLKNHGFEVIDLGKDVPAARIVEAAEEHKAAVIGLSALMTTTMVRMEDTVRLLRDKGLAIPVMVGGAVVTEAFAKSIGAAAYATDAVDAVRQAKA
LAG
>tr|E5Y8U3|E5Y8U3_BILWA Homocysteine S-methyltransferase OX=563192 OS=Bilophila wadsworthia 3_1_6. GN=HMPREF0179_02601 PE=4 SV=1
MADFRSALASGRTLLLDGGMGTMLQARGLPAGEHPEQFCLDRPDVLRGIHADYLAAGADIILTCTFGGSRLKLPAGIDVTPFNRTMARIARAAVGREAFV
AGDMGPCGQFVRPLGDLHPLELYEALREQARGLVEGGVDLFLIETQFDLAEVRIAVAAIRAESDLPIMVSMTFEQGTSLTGTTPEIFAETMQNLGVDALG
LNCGLGPEQMAPLMERFLACSSVPVLAEPNAGLPEL-VDGKTVFRLPPEPFAEKTAAFVGMGARLVGGCCGTTPDHIAALRRAVDAVPCPAPAVTPS-GI
VLTTRTRLVRVSPAEPFKIIGERINPTGKKDLQAELQAGEYGLAMRFASEQVALGAPILDVNVGAPMVDEALLLPELVQRLTGKYAEPLSLDSSHAEAIA
AALPFCPGSPLVNSISGEADRMEHLGPLCRQWGAPFILLPIQGRKLPVKAADRIAIIENMLDKAAMLGIPRRLVLVDVLALAVASKAEAAREGLETIRWC
AAH-GLATTIGLSNISFGLPARELVNTTFLSMAMGAGLSSCIANPSSGRLREAKAAGDVLMGHDRDAAAFVNGYAMWTPT-----ADAAAFA--RATAQT
VEEAVILGDRESVVGLVEKELEAGADPFELVRGRLIPAITEVGSKYERREYFLPQLLRSAETMQTAFARLKPLLEREANAEAQKIIVVATVEGDIHDIGK
NIVSLMLGNHGFKVVDLGKDVKAEAIVEAAVAHKADLIGLSALMTTTMVRMRDTVDLVKQRGLGVDVMVGGAVVTPAFAESIGAN-YSSDAVDAVRLAKS
LIA
>tr|D0X0X3|D0X0X3_VIBAL 5-methyltetrahydrofolate--homocysteine methyltransferase OX=674977 OS=Vibrio alginolyticus 40B. GN= PE=3 SV=1
--NVRQ---K-RILLIDGGMGTMIQGYKLE---NNDLLVLSQPQLIKEIHAAYLEAGADILETNTFNATTIAMADEMESLSINFAAAKLAREVADKPRYV
AGVLGPTNRT---YRNVSFDELVEAYSESTRALIKGGSDLILIETIFDTLNAKACSFAVESV-ELPVMISGTI-SGRTLSGQTTEAFYNSLRHVKPISFG
LNCALGPDELRPYVEELSRISESFVSAHPNAGLPNA------EYDLSPEDMAKHVKEWAQSGLNLIGGCCGTTPEHIRQMALAVENIAPR-------PVA
CRLSGLEPLAIDKDSLFINVGERTNVTGSARFKRLIKEELYDEALDVARQQVENGAQIIDINMDEGMLDAQACMVRFLN-----SKVPIMVDSSKWEVIE
AGLKCIQGKGIVNSISLKEGKEK--AKLIRRYGAAVIVMAFDEIGQADTRERKVEICTNA---VDEVGFPPEDIIFDAI----EEHNNYAVDFIEAVGDI
KR---LPHAMGVSNVSFSFR-REAIHAVFLYHCFKNGMDMGIVNAGQLE-------DVVLNRRDD-TERLLDIAAE------------------W-VEKR
LEHALVKGITEFIVDDTEEARVKASKPLEVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAHLEPYINAE----QT-KILLATVKGDVHDIGK
NIVGVVLQCNNYEIIDLGVMVPCEKILKVAQEEN------------------------------------------------------------------
---
>tr|D7ADT0|D7ADT0_GEOSK 5-methyltetrahydrofolate--homocysteine S-methyltransferase, cobalamin-dependent OX=663917 OS=Geobacter sulfurreducens (strain DL-1 / KN400). GN= PE=4 SV=1
MQPFLQAIAE-RVLVLDGAMGTMLQERGLRPGQSPEELNLTLPEVVAGVHREYLDAGADIIVTNTFGGSRAKLEHGLDRVAINARAVAIAREVCGDRAYV
AASIGPTGQFVEPVGDVSFDEMAAIFREQAQALIDAGADLITLETFLDIKEIRAAVIAIRGISEIPVIAQLTFDEGRTVLGTSPEAAAVTLEAAGADIVG
SNCGLGPDGICDVMAAMRRVTLLPLISQANAGLPTL-VDGATVFPGTPDDMTAFHDRLLDLNVRIIGGCCGTTPAHIRAIREALALRDQSLRAGPPEGVT
FLSSRTTVVAIGAGLPAAIIGERINPTGKKGFAQELREGKVSYIRREALEQTARGAVLLDVNVGTPGIDEPAAMERAVVTVATAVGAPLVLDSSDPAALE
RGLKAADGKVLLNSVNGEAKSMERILPLARKYGAAVIGLALDETGIPETAEGRLAVAERIVEAAGKAGIRRSDVVIDCLTLTVSAEQKRAMETLRAVRLV
KERLGCPTVLGVSNISFGLPRRPLISSAFFAMALAAGLDAAIVNPKEEEMMAAWHSSMVLLNRDPNAAAYIAAYAGAPPA-----AEPAAAGELPDIRQR
LARAVITGDGEGIVSLVEEALSQGLEPLQVSNEGLLPGLEEVGRRFEKNQVFLPQVMQSAEAMQAAFSRLRQEMAGE--AEAKGTILMATVEGDIHDIGK
NIVCTLLENHGFRVIDLGKNVPADRIVAEAERNGADAVGLSALMTTTMTEMENVLARLRAAGIRTFTMVGGAVVTQEYADRIGADLYARDAMEAVARIKA
LLG
>tr|C8X153|C8X153_DESRD Homocysteine S-methyltransferase OX=485915 OS=Desulfohalobium retbaense (strain DSM 5692). GN= PE=4 SV=1
MSAFRKALQGNKVLIFDGAMGTLLQSRGLVPGQSPEQFGRSNPEAVAAAHRDYLEAGADVITTNTFGGTAYKLGTDIDVRAFNAQMAAVARKEAGDKHFV
AGSVGPTGHMVRPLGNVGFTDLVQAFRTQIRGLVEGGVDCILAETHFDLAEAKAVVVAARQECDLPVGVSMTFEGGCSLTGTPPHCFVDTMQNLDVDLLA
TNCSAGPEQLVEVVRDMLPRLQTPLLVEPNAGLPEL-IDGETVFNLGPEAFAQQMRQFVELGVGCVGGCCGTSPDHIRALGRECPEKSAAANSVFSPPPV
VVTSRFGSVTLGPKSPLALIGERINPTGKKDLTAELQAGELQRACALAAEQVQAGATVLDINVGAPLVEESQLIPELVLELSRRQQVPLCLDSADPDAIE
LGLQAAPGSPLVNSISGEEGKMERLAPLCVRYGAPFILLPLEGGALPVSAESRLSIIQRLIDKALALGVPKRLIVVDALALTVSSKPEAARACLETIRAC
QERWAVPSVLGLSNISFGLPARELLNSTFLTMATGAGLSGCIANPGSVRLQEALAASEVLLGRDPQAQHFIQGYAEWTPA-----RATASGGGEEER-TV
LQRAVIKGETEVVTREVQEALRQGSQPFELVNNELIPGIMAVGEKYEKKEYFLPQLLLSAEAMQAGFELLRPLLEAAKDQEKPKKIILATVEGDIHDIGK
NIVALLLRNHGFEVVDLGKDVPAETIVQAAEEHEAELIGLSALMTTTMVKMEQTLELVRKRGLSTQVLVGGAVVTPEYARVIGAHGYAADAVGAVKKAKE
LVA
>tr|A5GCJ3|A5GCJ3_GEOUR Methionine synthase (B12-dependent) OX=351605 OS=Geobacter uraniireducens (strain Rf4) (Geobacter uraniumreducens). GN= PE=4 SV=1
MQPFLQAMKE-RVLVLDGAMGTMLQERGLKPGQSPEELNLTMPDVVAGVHREYIEAGADIIVTNTFGGNRAKLAHGLAKVRINARAVEIARKVAGEHAYV
AASIAPTGRFVEPVGDASFDEMCDIFREQAQALIDAGVDAISFETFLDIKEIRAGIIAVREIAAIPIIAMLTFDKGRSVLGTPPESAAITLEAVGADIVG
SNCGLGVEGIYEILSAMRRVTRLPLISQANAGLPVL-KDGKTIFPATPAEMTAYHDRMLELGVRIIGGCCGTTPAHIRAIKAALAEKDQSVRAGPAEGIT
WLSSRGGFTALGKGRPVAVIGERINPTGKKGFAAELREGKVSYIRREALDQVAAGATLLDVNVGAPGIDEPAAMERAVFCAGSAVSVPLVLDSSSPEALE
RGLKAADGKVLINSVNGEEKSLARVLPLAKKYGAAVIGLTLDEKGIPETAEERTAVAQKIAERALSLGISRKNVVIDCLTLAVSAEQKRAMETLSAIRLV
KGRLGLNTVLGVSNISFGLPCRPLISSAFFAMAMEAGLDAAIVNPKEQAMMDVWRSVMVLLNRDPNAAAYIDAYKGVATL-----AGTQVQEPPQDIKGR
LAKAVIDGDVENIVALVETAFAEGLSPLDISNGGLLPGLEEVGRRFEKNIVFLPQVMLSAETMKTAFARLKQEMKGM-SLESQGKILMATVEGDIHDIGK
NIVCTLLENHGFEVIDLGKNVPAARIIAEAKAHDVDAVGLSALMTTTMSEMENVVRQLKAAGVKTFTMVGGAVLTQEYATEIGADLYAKDAMEAVARIKA
ILG
>tr|A1VDP9|A1VDP9_DESVV Methionine synthase (B12-dependent) OX=391774 OS=Desulfovibrio vulgaris subsp. vulgaris (strain DP4). GN= PE=4 SV=1
MPDFRQALRAGRRLLFDGGLGTMLQARGLPAGVSPEQFCLDRPDVLRGIHADYVRAGADILTTNTFGGSRFKLGDGFDVVDFNRRMAAIAREAAGRQAFV
AGSIGPTGHFVKPLGEVEPAALVAAFREQVRGLVAGGADLLMIETQFDLAEARAAVVAARAECSLPIAVSMTFENGVSLTGSTPEVFVATMLNLGVDLLG
TNCSAGPDQMHDVVASLLASASVPVLVEPNAGLPEL-IDGKTVFRLPPAPFAEKTAAFAAMGARVLGGCCGTTPDHIAALRQAVADIPATLPVDSGV-GI
VLTTRSHLVRVGGDAPVRIIGERINPTGKKQLIAELQAGDFSLALRFSDEQVEAGAPILDVNVGAPMVDEEVLLPDLVQRLITRHGVPLSIDSSNAAAIE
RALPYCPGSTLVNSISGEPGRMERLGPLCRDHGAPFILLPLKGRKLPVAATERIAIIEELLVQAEGLGIPRRLVMVDVLALAVSSKAEAARQCLETIRWC
TAN-GFATTIGLSNISFGLPARELLNGTFLAMAAGAGLSSCIAHPGNGRIRETVACADVLLARDANAERFIDAYAAWTPV-----ASGPGLAS-QPPATT
LEEAVVKGDRDGVTAIVESELAAGADPFDLVQTKLIPAINEVGVKYERREYFLPQLIRSAETMQTAFRRLQPLLEEMRGAEVRPVIIMATVEGDIHDIGK
NIVSLMLGNHGFEVVDLGKDVKAETIVDAAETHGARIIGLSALMTTTMVRMEDTVKLVRARGLDVKVIVGGAVVTKAFADAIGADGYSADAVEAVRLAKS
LLA
>tr|H1L4B8|H1L4B8_GEOME Homocysteine S-methyltransferase OX=691164 OS=Geobacter metallireducens RCH3. GN=GeomeDRAFT_0865 PE=4 SV=1
MTPFLQAIKE-RVLVLDGAMGTMLQERGLRPGQSPEELNLTMPDVVAGVHREYLEAGADIIVTNTFGGTRPKLEHGLEKVRINARAVEIAREVCGDRAYV
AASMGPTGLFVEPVGEATFDAMAAFFREQAAALIEAGADLITLETFLDIKEIRAAVIAIREVSTIPVIAQLTFDEGRTVLGTPPEAAAVTLAAAGADIVG
SNCGLGPDGICAVLGAMRGVTRLPLISQANAGLPKL-VDGKTVFPGTPDDMTAFHDRMLGLNVRVIGGCCGTTPTHIRAIKEALAGRDQSWRDGPPAGVT
FLASRTSVVALGGGLPAAIIGERINPTGKKAFAQELREGKITTIRREAMEQTAAGAHLLDVNVGTPGIDEPAAMERAVFCVTGSVAVPLVLDSSDPAALE
RGLKAADGKVLVNSVNGETKSIERVLPLVKKYGAAVIGLALDETGIPETAEGRLAVAERIVAAAEGRGISRNDVVIDCLTLTVSAEQKRAMETLRAVRLV
KEIIGCPTVLGVSNISFGLPRRPLISSAFFAMALAAGLDAAIVNPKEEEMMAAWRSAMVLLNRDPSAAAYIAAYAGAAAA-----PEPAASGEALDIRER
LKRAVITGDRENIVALVEEALGQGLEPLQVSNEGLLPGLEEVGRRFEKNLVFLPQVMQSADTMQAAFGRLREVMKGS-PAASRGKILMATVEGDIHDIGK
NIVCTLLENHGFEVIDLGKNVPADRIVGKARELGVDAVGLSALMTTTMTEMENVIARLKEAGIRTFTMVGGAVVTQEYADEIGADLYARDAMEAVARIKA
LLE
>tr|E6VR40|E6VR40_DESAO Homocysteine S-methyltransferase OX=643562 OS=Desulfovibrio aespoeensis (strain ATCC 700646 / DSM 10631 / Aspo-2). GN= PE=4 SV=1
MPDFRSILRDDRIYFFDGGYGTLLQGRGLPPGLSPELWGLKAPEVIRGVHQEYLEAGADILTTNTFGGSRPKLGLDADPYELNRAMTRIARQVAGDRAFV
AASIGPTGHFVEPLGDLTFRELVEIFKEQIRGCVDGGADLILGETHFDLAEARAVVVAARLVCSLPVAMSMTFEGPASLTGTTPLTFVDTMQNMGVELIG
TNCSAGPEQMRDTLAAWAPRLTVPCFAEANAGLPELDAEGNTAFRLGPEPFAEQAVRFVDLGAKFIGGCCGTTPEHIRAVRGKVGDTPWRRPAPTDDAQM
VLTSRSVSVPVGFSHPGVIIGERINPTGKPLLTSELQDGVFAEALRFAAEQIDLGAPVLDVNVGAPMADEKILLPGLIKALSGRFTTPLSIDSNDSGAVE
AGLWVYPGSPLVNSISGEPGKMEALGPLCKLFGAPFILLPIVGRKLPVTATERLAVIEDLLVEAEGLGIPRRLIMVDALALTVSSKPEAARHSMEVMRRC
RDDWGLPTTIGLSNISFGLPARELLNSTFLALSMASGLCSFIANPNSARIQETLHAAEALLNRDPQAARYIGRFSDWT-A-----APTARAATDTPDLPP
VQAAVIKGDKGGVVPLVEAELDRGMTAMSIVNDLLIPGILVVGEKYERKEYFLPQLLQSAETMQVAFARLKPLLEADGGSADRPVVVMATVEGDIHDIGK
NIVCLMLKNYGFDVVDLGKDVAAERIVDAAQERGAAIIGLSALMTTTMVRMEDTVRLVRERGLKTKVIIGGAVVTEKFCTAIGADGWSTDAVRAVKLAQS
LVA
>tr|C7LWR6|C7LWR6_DESBD Homocysteine S-methyltransferase OX=525897 OS=(Desulfovibrio baculatus). GN= PE=4 SV=1
MRDFRQTLKGGNVLIFDGGMGSLLQRRGLQAGQSPEEFGMGRPDVVASIHAEYARSGANVVTTNTFGATRYKLPQGFDVFEVNETMTRAARQAVGDAVFV
AGSVGPTGKMIKPLGDISFRGLVDVFKEQIRGLAAGGADLILGETHFDLAEARAVVVAAREVCDLPVGISMTFEGGVSLTGTTPEVFAQTMENMGVDLIA
SNCSAGPEQLIEVAKAMLRVSRTPVLIEPNAGLPEL-VDGATVFRLPPDPFAATVSTLVDVGVSCLGGCCGTTPEHIKALTALCAGKTVRRQEISAPPCL
IVTSRSQAVEFGFDRPCRIIGERINPTGKAELTAELQRLETRRLMTYAEEQVARGADLLDVNVGAPMVEEARMLPLAVQALTSAHAIPLCLDSSDISAIR
AGLEAYPGSALVNSISGEEERMETLGPLCRDYGAPFILLPLKGRKLPVTAAERLAIIEELLIKAESLRIPRRLILVDALALTVSSKPEAAKACLEVIRHC
RERWGLGSTMGLSNISFGLPARDLINSTFLAMAMGVGMTSFIANPNAARIRENLAAAEVLLGRDSQAAGFIASYAGWNPV-----AAVASTAVDEDG-SP
VAVAVIKGQKDRIVDLLRERIAAGEDPFVLVDGEMIPAIAKVGEKYEKKEYFLPQLLLCAETMQIGFESIKHLLVREGQ-EAKATIVMATVEGDIHDIGK
NIVCLMLKNFGYDVVDLGKDVAAADIVAAAMAHKASVIGLSALMTTTMVRMEDTVRLVREQGLACRVMIGGAVVSQSYADLIGADGYADDAVAAVRVATR
LCA
>tr|Q1JWJ4|Q1JWJ4_DESAC Homocysteine S-methyltransferase OX=281689 OS=Desulfuromonas acetoxidans DSM 684. GN=Dace_0403 PE=4 SV=1
MNRFLEAIQQ-RVLILDGAMGTMLQARGLAAGGCPELMNLEKPEVVEGVHRDYAQAGAQIIVTNTFGGTRSKLEHGLDKVYINVQAARLARAAADPNDFV
AGSIGPTGRFVEPVGDATFDEMVEIYAEQVKALVAGGVDLLTCETFLDIRELKAAVMACREYADVPVMAMMTFDGGRTVLGTPPAAAAVMLEGLGVDVVG
TNCGLGIDGMYELLGQMRDVCSCPLIAQANAGLPIL-KDGETIFPATPVEMTSHHDQLIALGVRVLGGCCGTTPEHIRVMRQAMDERGQQWTA--PARRG
VLSSRTQVVAVGPEQPCAIIGERINPTGKKGYSAELREGKTAYIRREAQQQTGAGATLLDVNCGAPGADEPLALERAVHAITGVVGTPLVLDSSDPIALE
RGLKAADGKVLINSVNGEEKSLATVLPLAKKYGAAIIGLTLDGQGIPQTAEGRVEIAERIIERAQAVGIQRCDIVIDCLALTVSAEQGQAIETLKAIRTL
TQDHGMATVLGVSNISFGLPRRPLMSSTFFAMALQAGLSAAIINPKDQAMMDAFRSAMVLLGKDLRAERYIDAYAEETAP-----AVAAVAGAEPSIRER
LAQAIIDGDQDGVVALVELALKDGLDVLQISNEGLLAGLEEVGRRFGANRIFLPQVLLSAETMKTAFARLRQEMKGE-QVASLGKIMMATVEGDIHDIGK
NIVCTLLENHGYEVIDLGKNVSAAHIVEQAQAAHVDAVGLSALMTTTLQQMQITIDALKEAGVKVFTMVGGAVVTQDYADEIGADLYAEDALEAVAKIKQ
MLH
>tr|B8J0R7|B8J0R7_DESDA Homocysteine S-methyltransferase OX=525146 OS=Desulfovibrio desulfuricans (strain ATCC 27774 / DSM 6949). GN= PE=4 SV=1
-MTFRQALGSGRPLLLDGAMGTMLQASGLPAGTSPEEFCMENPDILRGIHASYLKAGVDLLTSCTFGGNAYKLSKNLDVFSFNKRMASVARAAAGRPIFV
AGNVGPTGHFAKPLGPVEPAELIEVFAQQIRGLVAGGADLVFIETQFDLAEARAAVVAARQVCDLPVMVSMTFEQGVSLTGSTPAIFAETMQNMGVDVVG
TNCSLGPEQMEPVVAELLGVCACPVMAEPNAGLPEL-RGTQTVFPLGPEDFARKTASFAHMGAQVLGGCCGTTPEHLAALAHSLRGLGEVRPTGVKRSGI
CLTSRSQMVRIGAGRPLAIIGERINPTGKKQLTLELQEGRFDTALQFADAQIEAGATVLDVNVGAPLVDETALLPDLVQRLVGRLTVPLSLDSSNAQAIA
AALPYCPGSFLVNSISGEEGRMELLGPLCRDYGAPFILLPLEGATLPEKAVERIRTVESLLLRAERLGIPRRLMMVDILALAVSSSPDGARQCLEMTRWC
AEQ-GLPTTLGLSNLSFGLPARDLLNATFLAYAAGAGLSSCIANPSAQRLREAADALKVLGEHDPHASSFISSYANWKPV-----LQRQGGGG---ASKS
LGEAVLNGDRENVLSLLEAELAAGAEPFSLVQEVLIPAITEVGARYERREYFLPQLIRAAETMQTAFGHLKPRLEAGRGAEERPVVIMATVEGDIHDIGK
NIVSLLLGNHGFDVIDAGKDVPAEDIVACALEHNARIIGLSALMTTTMVRMEDTIKLVKEKGLAIKVMVGGAAVTQAFADAIGADAYCADAVGAVRAAKN
FM-
>tr|F3Z3X5|F3Z3X5_DESAF Methionine synthase OX=690850 OS=Desulfovibrio africanus str. Walvis Bay. GN=Desaf_2098 PE=4 SV=1
MPDFRTALNDQALHLFDGAYGTLLQKRGLPAGMSPELFGLERPDVLRGLHEEYLAAGARILTTNTFGGTAPKLGKGVDVRAFNRATVEIARQAADDRAFV
AGSVGPTGLFVEPLGPISFRDMVALFIEQIRGLVEGGADLIKAETHFDLAEAKAVVVAAREVCDLPVLVSMTYEGKTSLTGTPPDTFVDTMQNLGVDVVG
VNCGTGPEEMAALVELMRRRLETRYHVQPNAGLPRL-ENGRTVFPLGPEEFATKTARFAELGAKFLGGCCGTSPEHIAALAAALQGKTWTRLAPPENPCL
VLTTRGGSVAVDHALPLVLIGERINPTGKKKLAEELQSGVFGEALSMAAEQLATGAGILDVNVGAPMVKEAEVLPALVKALSERFDAPLAIDTTDIQAMA
ASLWACAGSPLVNSISGEPGRLEELGPLCKKLGTPFILLPLAGKKLPVTASERLAAIESLLRKADDLGIPRRLIMVDALALTVSSKPEAAKSCFSVIRHC
RDVWRLPTVLGLSNISFGLPARELVNSTFLAMCMAEGLTACIANPGSTRLREALAAAEVLLGRDPQAGRFIAGFSAWKPS-----AGLRMSGPDAAA-AT
PREAVIRGDKERLVPLLEAALERGDNPFDLVDKELIPGIMEVGEKYERREYFLPQLMLSAETVQLGFERLRPLLEQSGRDEARPRIVMATVEGDIHDIGK
NIVCLLLRNHGFDVLDLGKDVPAAAIVDAARCHDARLIGLSALMTTTMVRMEEVVKLVRESGLQAKIIIGGAVVSQRYAEAIGADGYAKDAVAAVRLAKQ
LVS
>tr|E1K0Y3|E1K0Y3_DESFR Homocysteine S-methyltransferase OX=596151 OS=Desulfovibrio fructosovorans JJ. GN=DesfrDRAFT_3533 PE=4 SV=1
MGDFRKALTDAGLLVFDGAMGTLLQGRGLAPGQSPELFGLSHPEAIVATHREYIEAGSRVITANTFGGSRYKLPAGTDVVALNREMAHLARQAAGSTAFV
AGSVGPTGQFVAPLGKVTLRELVAAFVEQIRGLAAGGCDLIVGETHFDVAEAKALVLACREVCDLPVAVCMTYEGAASLTGSAPEVFVDVMENLGVDLIG
VNCGAGPDDMRHVGEVYSRRLSTPFFVKPNAGMPRL-ENGQTVFPMGPEEFAEKTARFADLGAKALSGCCGTTPAHIAALAKALSGRSWTRPEAPDRPVL
AVASRALTVALGGKSPCAVIGERINPTGKAELAAELVAGEYAKALAFAEEQAAAGASILDVNVGAPMVDETKTLPGLALELTKRQRLPLCLDSNNAEALT
NALWASPATPLVNSISGEPGRMELLGPLCRDHGAPFILLPLKGRKLPVTAAERLAIIEELLAQAESLRIPRRLILVDALALTVSSKAEAGLACLETIRHC
REAWGLPTVLGLSNISFGLPARELVNAAFFAMCLGAGLAAAIANPNVARLMETGAACEVLLDRDPQAGRFIERYAGWKSA-----PAAAA--KSEEGGSP
LRQAVIKGRRAELDGLIDAALAEGRSPASILSEELIPGIMEVGERYERKEFFLPQLLVAAETMRAGFTRLEPLLAETSGAE-KARIVMATVEGDIHDIGK
NIVCLMLKNHGFEVIDLGKDVPAARIVDEAQQRKADIIGLSALMTTTMVRMEDTVRLVKERGLTAKVMVGGAVVTAAFAKSIGADAHAADAVDAVRQAKA
LIG
>tr|Q3A0Z9|Q3A0Z9_PELCD 5-methyltetrahydrofolate--homocysteine S-methyltransferase, cobalamin-dependent OX=338963 OS=Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1). GN= PE=4 SV=1
MADFIAAIKQ-RVLVLDGAMGTMLQERGLKAGGCPEEMNLTAPDVVEAVHREYADAGADIIVTNSFGGSRPKLAHGLDKVHINARAVVLARNAAGPDRFV
AASIGPTGRFLRPVGDADFDDMVEVFGEQVRAFAEAGADLITMETFLDIAELRAAVIACRRYSDLPIMALMTFEEGRSVLGTSPEAAAVTLEALGVTVIG
TNCGLGVEGIYEMLARMRSVCSTPLIAQPNAGLPQL-IDGQTVFNATPQDMVVYHQQLLDIGVRVIGGCCGTTPAHIRAMREALQGTEQDWTP--PARRC
LLSSRTGVVEIGGPAACAIIGERINPTGRKAYAQELREAKTAYIRREAQAQVAAGAHLLDVNCGAPGVDEPAALERAVLAVEGVAQVPLVLDSSDPAALE
RALKVADGKVLINSVSGEEKSLKGILPLAKKYGAAVIALALDGSGIPETAEERLAVARRIRDAALEAGLAPEDIVVDCLTLTVSAEQKRAMETIRTLRLV
RDELGLPTALGVSNISFGLPCRPVLSSVFFAMALDAGLSAAIINPRDERMMDAYLAAMVLLGKDVRAESYIAAYADSAAP-----AAAAPQDAPTGIRDR
LAAAVIEGDKDGVVALVEQALTEGLDTATISNEGLLPGLEEVGRRFGENRVFLPQVMQSAETMQTAFGRLKQEMQGA-SVASLGRILMATVEGDIHDIGK
NIVCTLLENHGFEVIDLGKNVSADRIVEQAVELKVDAVGLSALMTTTIEQMRVTVDRLRAAGVKVFTMVGGAVVTQEYADEIGADMYAADALEAVAKAKK
LLA
>tr|D9YDT6|D9YDT6_9DELT Vitamin B12-dependent methionine synthase family protein OX=457398 OS=Desulfovibrio sp. 3_1_syn3. GN=HMPREF0326_01659 PE=4 SV=1
MMTFRQALGLGRPLLLDGAMGTMLQASGLPVGMSPEQFCMESPQVLRGIHKAYLDAGVDLLTTCTFGGNPYKLPKELDVFAFNKRMAEVAREAAGRPVFV
AGNVGPSGQFAKPLGPVEPRELIAGFAAQIRGLVAGGADLIFVETQFDLAEARAAVVAARRECDLPVMVSMTFEQGVSLTGSSPAIFAETMQNLGVDVVG
TNCSLGPDQMLPVVRELLETCACPVMAEPNAGLPEL-RGNVTVFPLGPEEFAQKTAAFAGLGARILGGCCGTTPRHLAALAQAVRGMDYSPSEAARRDGI
CLTSRSQLVRIGAGEALVIIGERINPTGKKVLTQELQEGRFDAALQLADQQVEAGAGVLDVNVGASLVDETSLLPELAQRLIGRLTLPLSLDSSNAEAIA
KALPYCPGSFLVNSISGEADRMDVLGPLCRDYGAPFILLPLQGAKLPVQASERIRIVENLLERAAGLGIPRRLVMVDILALAVSSKAEGGRQCLEMARWC
RSQ-GLPTTLGLSNTSFGLPARELLNATFLCMAAGAGLTSCIANPSATRLREAVDAMRVLGAHDPHAESFIASYAEWKPT-----LRQGDKAG---AAKT
LGEAVLTGDKENVLPLLEAELEAGADPFALVRDTLIPAITEVGARYERREYFLPQLIRAAETMQTAFSHLKPRLEANRGPEERPVIVMATVEGDIHDIGK
NIVALLLGNHGFDVVDAGKDVPAEAIVACALEHNARIIGLSALMTTTMVRMEDTIRLIRERDLPIKVMVGGAAVTQAFADAIGADAYCPDAVCAVRAAKT
FV-
>tr|B6WT17|B6WT17_9DELT Putative 5-methyltetrahydrofolate--homocysteine methyltransferase OX=411464 OS=Desulfovibrio piger ATCC 29098. GN= PE=4 SV=1
-MKFVQRLAERRPLLLDGAMGTMLQASGLPAGVSPEEFCMERPDILQGIHKAYLDAGVDIITSCTFGGNPCKLPASLDVFTFNKRMVETARAAAGRPVFV
AGNVGPSGHFARPLGDMEPEELIKAFSEQIRGLVAGGADLIFIETQFDLAEARAAVTAARQVCDLPVMVSMTFEQGASLTGSSPTIFAETMQNMGVAALG
TNCSLGPDQMLPVVEELLSVCACPVVAEPNAGLPEL-RGSETVFPLGPEAFAQKTAAFAARGARVLGGCCGTTPRHLAALRQALESVSCDERPVVSPAGI
CLTSRSQLLRLGEGQPFSVIGERINPTGKKELTRQLQAGQFDEAFRLADEQLQAGARILDVNVGASLVDETVLLPDLVQRLVSRVDVPLSLDSSNAQAIA
RALPYCPGSFLVNSISGEAGRMELLGPVCRDFGAPFILLPLQGTKLPVRASERIAIVEKLLEQADALGIPRRLVMVDILALSVSSKPEGALQCLEMVRWC
RSQ-GLATTLGLSNVSFGLPARDLLNATFMAMCAGAGLSSCIANPSAPRLHEACDAVAVLQGSDSNAGSFIASYADWKAV-----RAGTGPGA---AAET
LGDAVLFGDLENVLPLLEKELAAGAEPFALVQDVLIPAITEVGTRYERREYFLPQLIRAAETMQKAFAHLKPLLEKSRGPEERPVIVMATVEGDIHDIGK
NIVCLLLGNHGFDVIDAGKDVPAEQIVACALEHKARIIGLSALMTTTMVRMEDTIRLVRERDLPIKVLVGGAAVTQAFADAIGADAYCEDAVSAVRAAKQ
FVT
>tr|Q67LG1|Q67LG1_SYMTH 5-methyltetrahydrofolate S-homocysteine methyltransferase OX=292459 OS=Symbiobacterium thermophilum (strain T / IAM 14863). GN= PE=4 SV=1
-MKLEDMLGR-EVLVFDGAMGTMLQAQGLAPGACPDVWNLERPEDVIAVHRAYVEAGAQILETNTFGSTPIRLGHGLRCRDIVVAGVRCAREAAARW--V
AGSMGPLGALVEPLGELPFDEAYAQFAVQARAFAEAQPDFIIIETIADLNELRAAVLACRDHAPIRIIAQITLDSGRAFTGTDPETAALVLQSLGADVIG
FNCSVGPDLLVEAVARMARVARVPISVQPNAGLPLL-QDGATRFPMGPEEFAAYGPKLVEAGAALVGGCCGTTPEHIRRLRAAVEGLKPPARPGP-LAHL
GLASRTRSLFFVEQNLPVVIGERINPTGRKLLTRDIREGAFQRVRAEAKQQVEAGAAVLDVNVGVPLIDEPAAMARAVRVIQDAVDVPLCLDSPDPAALE
AGLKACVGKPLLNSFSLEEGRAEAVLPLARRYGAAVLGLTIDEKGIPASAEQRLAIARRLVAAAEAHGIPRHDVVIDPLALTAGAQQAEAKETLKAIRWI
TDELGVLASLGVSNISFGLPNRHFLNAVYLSMAVTEGLAMAIMNPLDERMMDTVRALRLFLNRDRNAAVYMKRLKAAAAG-----EIAAVTS--SGDPAD
LHDAILEGDREAIVPLVEQGLAEGRDPMDMLNRHLIPAIEEVGRLFGEGIYFLPQLMLSAQAMKKAFARLKPEI--QKAQTEIGTVVLATVQGDIHDIGK
NIVAVLLENYGFRVVDLGRDVKNEVVLEEARKVGADMVGLSALMTTTMPQMKRVIELFAREGFDCPVIVGGAATTKAFAEQIGARGHGRDAQEAVALALE
VLK
>tr|D7CLC9|D7CLC9_SYNLT Homocysteine S-methyltransferase OX=643648 OS=Syntrophothermus lipocalidus (strain DSM 12680 / TGB-C1). GN= PE=4 SV=1
-KDLASLLRE-RIIILDGAMGTMLQERGLRPGDCPELFGLEHPEVLEEIHGQYIEAGADIIQTNTFGANRFKLTEGLRVAEINKAAVKAAKKVAGGL--V
AIDIGPTGRLLQPAGDATFDQLYEAFREQVVAGAEAGADLVSIETMTDIGELRAAVIAARENTDLPILAHLTFENGRTMMGTSPAGAALVLEALGVTAIG
ANCSGGAKELLPVIEEMARVTGIFLSVEPNAGLPKL-ENGRTIFPETPESMAVYALSLREAGANLIGGCCGTTPAHIRAMAEILRGLPPVTRRPK-RV-R
ALASRSRYVVLSEDSPLHFIGERINPTARKKLGQDIAQGSMAMVAEEARKQVEAGAPLIDVNVGVPGIDEPSAMEKAVIAVQSSVDVPISIDSANSAAVE
AALKAFVGRPLINSTTGEQKVLERILPLAKKYGAAVLGLCLDEKGIPSTAGERFEIAVRILEQARLYGLREEDIYIDCLVKTAGAEQAQVMETIKCVRMV
RERLGLATVLGISNVSHGLPAREILNSTYLAMALGSGLDLPIINPFDQRIREVILASGVLLNRDISARKFVGEFRTSLSE-----AARRIKE--EG-GAD
IEEAVVKGEEHLIVGLVKEALAAGIAALEVVNKSLIPGIEKVGELYEKQEYFLPQLMLSAETMKKGFATVRPFL--TQQQQQFGTIIMATVEGDIHDIGK
NIVSLMLENYGFKVIDLGKNVPAQRIVEEAVRSRADIVGLSALMTTTMPRMGEVIERLREKGLGCRVMVGGAVLTQEYAERIGADAYARDAREAVIKARK
LCN
>tr|G5GES1|G5GES1_9FIRM Putative uncharacterized protein OX=679200 OS=Johnsonella ignava ATCC 51276. GN=HMPREF9333_00059 PE=4 SV=1
---MEDSAPG-KISILDGGMGTMLLAAGMKAGEHPEVFAFNNPGIVEDIHKKYIEAGSDIIYSCTFGANEKKLKGGITTLQAVLSAVKTAKKAA--EVKV
ALDVGPIGELLEPLGTLSFDEAYNIYKEVMSIGEEAGADLIVVETFTDLYDAKAALLAAKENTSLPVVVTMSFEGGRTFTGTTIPSMATVLTGLGADAIG
FNCSLGPKEILKFAEELVQWTDLPVVIKPNAGLPDP-VTG--KYNLNASDYASDMLAFKKFGVSMMGGCCGTDPEYINKLKCERDARADIKTAKSRKIRY
GVCSSSKMVELN---KVRVIGERLNPTGKPRFAQALLEHDMDYISRMAIEQEESGAQILDVNVGVPGADEPSLMIETVKAIQGITSLPLQIDSSNPAAIE
AGLRAFNGKAIINSVNADDERLDLILPIAKKYGAAVIGLSLSERGVPQTAQERFDNAVYILKKAIEYGLKKEDVFIDCLTLTVSAQQEQAVQTLNALRKV
KSELGLHCVLGVSNISFGLPERSHITESFLVQAMCCGLDLPIINPNVSSLMDAVYSYKVLSGEDENCSDYIMRFSA----------ISGDIK--C-DVHA
IEEAVLKGLKVQTREIAAKLLESM-SENDLINNKLIPALDIVGDKYEKQIIFLPQLINSANAACEAFELIKERLAKSNQGVSKGKIVLATVKGDIHDIGK
NIVKIILENYGYRIIDLGRDVPIENVVKAVIEEKVNLVGLSALMTTTLPSMKETIEAVKAVSPECKIWVGGAVLTPDYAMEIGADYYAKDARASVDIAKL
SFP
>tr|F7KA65|F7KA65_9FIRM Putative uncharacterized protein OX=658086 OS=Lachnospiraceae bacterium 3_1_57FAA_CT1. GN=HMPREF0994_02735 PE=4 SV=1
-MEFREFIKD-RMVFLDGATGSNLMLRGMPGGVCPEKWIMENTQVLIGLQKEYVAAGANILYAPTFTANRCKLKEGLQLRQINAVMVAASREAAGGKALV
AGDLTMTGEQLAPIGSMDFEELIDIYKEQIACIKEAGADLLVVETMMSLQESRAALLAAKEIPGLPVMVTMTFEDGRSLYGTDAATAAVVLESLGAAAIG
ANCSTGPEQMAGIIRQMASVTRIPVIAKPNAGLPSLNEEGKTVYEMRPREFAEEMQAVYEAGASIIGGCCGTTPEHIADLHESFAGK---MPAQ--VNIR
YLTSERKTIAFGLDDPFLIIGERINPTGKKKLQAQLREGSFEMVTRFAEEQEAGGASVLDVNMGMSGIDEKEMMLRALEEVGGVSQLPLSLDSSHVEVLE
AALRRYPGRALINSISLEKEKFEKLIPMAQKYGAMFILLPLSDAGLPESLQEKKEIIETILERAFACGLAKEDIIVDGLVTTVGANPKAALETLETIRYC
KEK-QLATVCGLSNISFGLPERSYVNSVFLTMAIQAGLTMAIANPSQELLVASAFASDMLLCKEESALRYIQKEGR-QSS-----GNGGSGT--AAGEKS
VYEAVLKGNRSGIEQITRRALEEGASARELLDTCLLPAINQVGELFDKGKYFLPQLISSAEAMKLSIGVLEPLLSSDGKQEKMPVVVIATVEGDIHDIGK
NLVALMLRNYGFEVIDLGKDVPKEKIIQAAKEHGAGIIGLSALMTTTMQEMRHVVELAHEEGLDSKIIIGGAVVTQDYADEIHADGYAKDAADTVRLAKR
LLG
>tr|G9YI84|G9YI84_9FIRM Putative 5-methyltetrahydrofolate--homocysteine methyltransferase OX=861450 OS=Anaeroglobus geminatus F0357. GN=HMPREF0080_01369 PE=4 SV=1
-K-LLDRLGK-EWLFFDGGTGSILQAEGLQPGELPETWNLIHPDKIISLHEHYLEAGCHIFNTNTFGANRLKFPD--TIDEIVTAAVRLAKKARRRDAYI
ALDIGPTGKLLKPMGDLPFEDAVSIFAEIVRIGAREGADLVLIETMNDSYEAKAAVLAAKENCDLPVLLTCVFDKGKMLTGGTPESIVAVMEGLGIDGIG
INCSLGPKEMLPTVKRLTAAASVPVLVNPNAGLPES-IDGETVYTIGPDEFATCMKEIARLGASAVGGCCGTTPEHIKKVIAAVSPLPFMPVKP--KHRT
VISSFSRTVTIGRDTAPVIIGERINPTGKKRFKQALLDHDIDYIVGQGLEQEEAGAHVLDVNVGSPETDEVELIQEVVGKLQSILPLPLQIDTSNPEAME
KALRMYNGKALINSVNGKEETMKAVFPLVKKYGGVVVALALDEDGIPPTADGRVAIAGKIYDKAAFYGIAKENIIIDGLCMTVSADPASALVTLETVRRI
HDELGGNTILGVSNISFGLPARELINSYFFAMALQSGLTSAIINPNNTAMMQAYRTYCVLTDKDPNFTEFIGAYRDYKTP-----DVDEAV----SKADK
LMDAIERGLANPAAEATRNALLTR-DALAIINEDLVPALDNVGHGFEKGTIFLPQLLMAAEAAKAAFSVVKESMK--DIQDVKGKVILATVKGDIHDIGK
NIVKVLLENYGYKVVDLGRDVSPELIVETAVKDDVKLVGLSALMTTTVVNMEETINQLHAKKPDCKIVVGGAVMTKQYADSIGADCYGKDAMSTVRYADE
LVA
>tr|A9KSG0|A9KSG0_CLOPH Homocysteine S-methyltransferase OX=357809 OS=Clostridium phytofermentans (strain ATCC 700394 / DSM 18823 / ISDg). GN= PE=4 SV=1
-MEFKAMIEQ-KIVILDGATGSNLQNAGMPSGVCPETWILDNKEVLITLQKEYLYAGTDILYAPTFTSNRIKLSEGLRIEEINHSLVELSKEAINRSIMI
AGDLTMTGEQLLPFGKMDFEELITIYKEQIGHLVSSGVDLLVVETMLSLQECRAAVIAAKEICELPVMVSLTFGDNRTLYGTDPKTAMIVLQSLGADAVG
VNCSSGPKKLSEVIEQMLPVANVPLIAKPNAGLPKL-VEDRTVFTMDADEFAASCKIFLELGVSILGGCCGTTPKHINLLNELAKTY--QAPVI--HKLR
VLTTERRSMEFSLVDRFLVVGERINPTGKKVLQAQLREGVLDLVSEMAIEQEELGADILDINMGMNGIDEKEMMLKVMDEVLQVTNLPLSIDSSHVSVIE
AALRRYPGRALINSISLEKEKFEKLLPVAKKYGAMFILLPLSDAGLPKDLEEKKQIIHTIVSAAKEIGLTAEDIVVDGLVNTVGANKEAAIQTMETIRYC
KEELSLATIVGLSNISFGLPERQFVNATFLSFAIQAGLTMAIANPSQDLLMNTAYAADLLRNKEGADLRYIKKVGESVRE-----ASNVNAN--ESNDNS
IYEAVIKGNKRKILALVIEEVNNKTSAAEILDTILIPAINQVGQYFDSGKYYLPQLIASAETMKTAIDYLEPMLKKDSKEEKVGTIIIATVAGDIHDIGK
NLVALMLKNYGFNVIDLGKDVSSEKIIETAKELDADIIALSALMTTTMLEMKRVVNYRNEASLRAKVIIGGAVITQDYCDEIGADGYSKDAQEAVNLVKK
LLK
>tr|G5II48|G5II48_9CLOT Putative uncharacterized protein OX=742737 OS=Clostridium hathewayi WAL-18680. GN=HMPREF9473_03176 PE=4 SV=1
-M-ILEAIRE-RIVFFDGGMGSLLQARGLGPGELPETWNILHPEVLREVHRDYLNAGCDVLTTNTFGANGLKYRSAHTVKEIVTAAVENAKAAVEE-GYI
ALDLGPTGKLLKPLGDLGFEEAYELYKEVVLAGAAAGADFVHIETMSDGYETKAAILAAKEN-QLPVTATMTFDKGKLLTGGDVYSAVALLEGLGVDALG
INCGLGPIQMKGILAEMLTAASIPVIVNPNAGLPRS-EGGKTVYDIDADEFAAVMEEIVRMGANAVGGCCGTTPEHIQKVVNRCAGLPQKYPEK--KHRC
VISSFAHAVEIGR--EPVLIGERINPTGKSKFKQALREHNLDYILREGVVQQDNGAHVLDVNVGLPEIDEPSMMEEVVRELQSIVDLPLQIDTSDVNAME
RAMRIYNGKPLINSVNGKEESMRAVFPLVKKYGGVVVALALDESGIPETADGRIAIAKKIYERAAEYGIEPEDILIDSLCLTVSSDSKGALTTLETVRRV
REELGGGTILGVSNISFGLPQREIINAAFFTMALQNGLSAAIINPNSEAMMRAYYSFRALADMDAQCGDYIRIYGGQTAG------LGATLP--KGGGTS
LGDSILKGLKDGAQKAVTSLLETK-DALTIINEEMIPALDTVGKGFEKGTIFLPQLLMSAEAAKSAFEIIKERMAKSGQQEKKGKIILATVKGDIHDIGK
NIVKVLLENYSYDVIDLGKDVPPELVVETAVAQKAPLVGLSALMTTTVPSMEETIRRLRVDAPWVKVMVGGAVLTEDYAKTIGADQYCKDAMASVNYAES
LFT
>tr|C4GEB2|C4GEB2_9FIRM Putative uncharacterized protein OX=626523 OS=Shuttleworthia satelles DSM 14600. GN=GCWU000342_02058 PE=4 SV=1
--------DN-KIIVLDGGMGTMLQAAGMPAGQHPEVFGHQHPEIVEQIHRQYIEAGSNVIYANTFGANARKLQGSIDTGKAVFSAIRTAKRAAQKEVRV
ALDLGPVGELLEPLGTLSFEEAYEIYREAVVAGYEAGADLIVAETFTDLLDIKALVLAAKENTPLPVWTTMTFESGRTFTGTTIASMALTLTGLGVDAIG
INCSLGPTEILPLIEELREWTHLPVIAKPNAGLPDP-RTG--VYDLTAEDFGKQMQAYAELGVSVLGGCCGTDPDYIRCL-------SRLREA---KVRK
GICSTTNVCEFG---GVRVIGERINPTGKKRFQQALREHDMEYICKMALDEEEAGADLLDVNVGLPGAEEKPLMLEVVRALQGVVSVPLQIDSSDPEVIE
AALRIYAGKAIINSVNADDAKLEAILPVARKYGAAVIGLALDEGGIPQTARERFEKAAYIKEKCLKAGMEADDIIIDALTLTVSAQQEQARETLEAVERI
SRELGLHTALGVSNISFGLPAREHVTENFLIQAMYCGLDFPIINPNILSLMDAVASFKALSGEDISCMHYIDRFAG----------SVSDSR--P-QAES
IDQAILKGLKQETRKLAEGLLEGL-TEVEVINRYLIPALDLVGDQYEKQTIFLPQLINSANAASAAFDMIKDRIAAQGSGKEDKKIVVCTVKGDIHDIGK
NIVKVILENYGYKVFDLGRDVPAGKVVDTVVAEDVRLVGLSALMTTTLPAMQETIDRLREASPHTKVWVGGAVLTREYAREMGADFYADDARESVEIAQR
VLG
>tr|Q0AX05|Q0AX05_SYNWW Methionine synthase (B12-dependent) OX=335541 OS=Syntrophomonas wolfei subsp. wolfei (strain Goettingen). GN= PE=4 SV=1
-PNLYTLLQS-RILILDGAMGTMLQERGMVPGECPELFGVNNPLILEDIHYQYMEAGADIIQSNTFGGNRFKLAEGLRVAEINAEAIRIARAGARKL--V
AASIGPSGKLLQPFGNADFAELYAAFTEQMLSCEKAGADLISIETMTDIGEMRAALIAACSNTRLPVIAHMTFEGGRTLMGTDPLTALIIMEALQPLAIG
ANCSGGARELLPIIEEMGRYSSVFLSVEPNAGLPQL-LGERTVFPDRPEEMAEYALKLRDVGANIIGGCCGTTPEHIKAIASTLRGLSPRKRTPR-RI-R
ALASRSQAVVLGEGKPLTFIGERINPTARKKLAQDIKEGRMQMVVDEARKQVEAGAAILDVNMGVPGIDEAMAMREAVVAVQAAVDVPLALDSTSAQAIE
EGLQSFVGRPLINSTTGEDKQLEIILPLAKKYGAAVLGLCLDQNGIPERAEDRVEIARKIFEQAREYGLREEDIYIDCLVKTASAEQSQVFETLKALRMV
KEEMALGTVLGVSNVSHGLPARELLNSTYLAMAWAAGLDLPIMNPFESRMMDANRAAAVLLNRDLNSLEFIEKYKAQDAR-----IVRNAEK--NM-PLS
ISQAVLQGDKGLLLEQVQKALQEKIAPMEIVNKALIPGIERAGELYDQKKYFLPQLMLAAESMKDAFTLVKTRL--SGEEEHKGLIVLATVEGDIHDIGK
NIVAILLENYGFKVLDMGKDVKAEVILDVAEKEKADIIGLSALMTTTMPRMQEVIQGVKARGMPCKIMVGGAVLNQEYADHIGADAYSEDARQAVLMAQR
LLG
>tr|E2ZDC4|E2ZDC4_9FIRM Putative methionine synthase OX=706434 OS=Megasphaera micronuciformis F0359. GN=HMPREF9429_01633 PE=4 SV=1
-Q-LRKRLGK-ERLFFDGGTGSLLQAAGLKPGELPETWNLTRADVIIDLHKQYLDSGCHIFNTNTFGANRLKYPD--NLDDIVTASIRLAKEARRLDAYV
ALDIGPTGKLLEPMGDLPFEEAVDIFADLVKIGVREEADLILIETMNDSYEAKAALLAAKENSDLPVLLTCVFDGGKMLTGGTPESMVAMAEGLGVDGIG
TNCSLGPAAMLSTVKRFVAAASVPVLVNPNAGLPES-IDGQTVYNVDAHEFAKEMKDIVEAGAHAVGGCCGTTPEYIQALIAEVEDIPFIPPTP--KHKT
VISSFSRTSLIGDEAQPLIIGERINPTGKKRFKQALIDHDIDYIISQGLEQEKAGAHALDVNVGSPEVDEVELIQEVVGKLQSILPLPLQIDTSNVEAME
KALRMYNGKALINSVNGKEETMEAVFPLVKKYGGVVIGLALDEDGIADTADGRVAVARKIYERAADYGIAKENVIIDGLCMTVSADPESALVTLETIRRI
HDELGGNTILGVSNISFGLPARELINSYFFAMALQAGLSSAIINPNNKAMMQAYRTYCALSGKDTNFTNFITAYQNYETP-----DVQKAV----DSDAK
LMEAVERGMAGPAAEATHNALLTR-NALDIINEDLVPALDNVGQGFEKGTLFLPQLLMAAEAAKAAFAVVKEALT--DAQETKGKVILATVKGDIHDIGK
NIVKVLLENYGYQAVDLGRDVAPETIVETAVKEDIRLVGLSALMTTTVVNMEETIRLLREKKPDCKVIVGGAVMTKQYADSIGADCYGKDAMSTVRYADE
LLE
>tr|C0D4W7|C0D4W7_9CLOT Putative uncharacterized protein OX=518636 OS=Clostridium asparagiforme DSM 15981. GN=CLOSTASPAR_04313 PE=4 SV=1
-M-LLREMRQ-RRLFFDGGTGSLLQAQGLKAGELPEVWSITRPEVCVKLHRDYLEAGADIIKTNTFGANGLKFKGEASVDEIVTAAMKNARRAVAE-GYI
ALDLGPTGKLLKPLGDLDFEAAVELYKEVVRIGRREGADLVLIETMSDSYELKAAVLAAKEAEGLPVFATVVFDKGKLLTGGNVESTVALLEGLRVDALG
INCGLGPVQMKGIVEELLKVSSLPVIVNPNAGLPRS-ENGVTLYDIDGDRFAQVMEEIARMGACFLGGCCGTTPEHIQKTVGRCKDVPLVLPQA--RKRT
VISSYSQAVCIEG--KTVIIGERINPTGKSKFKQALRDHNLEYILKEGVTQQDNGAQVLDVNVGLPEIDEPSVMEEVVKELQAIIDLPLQIDTSNPRAME
RALRVYNGKALINSVNGKAEVMDEIFPLVARYGGAVVALCLDESGIPETAEGRIQVAKKIIREAARYGIGTEDLIFDGLCMTVSSDSKGALTTLETLRRI
RDELGCKSVLGVSNISFGLPQREIINASFFTMAMECGLSAAIVNPNSEAMMRAYYSFNALMDMDPQCGEYIRIYGGQAGS------LGKTLP--RNAASR
LSAAIERGLREEAHRAVGELLETR-EPLDVINTEMIPALDRVGKGFEAGTIFLPQLLMSAEAAKAAFEVIKDRMASSGQQEKKGTIILATVKGDIHDIGK
NIVKVLLENYSYEVIDLGRDVPPKTIVQTAMERKVRLVGLSALMTTTVPSMEETIRLLREQLPGTLVMVGGAVLTPEYARTIGADAYCRDAMASVNYAEE
VFA
>tr|D6DIA6|D6DIA6_CLOSC B12 binding domain./Pterin binding enzyme./Homocysteine S-methyltransferase OX=84030 OS=Clostridium saccharolyticum. GN=CLS_19140 PE=4 SV=1
-S-LLHELAE-RILFFDGGTGSLLQAAGLKPGELPETWNIRRPEVIVKLHRDYLDAGCDIINTNTFGANRLKFNEEFGLKEIIEAAVRNAREAVNL-GYI
ALDLGPTGRLLKPMGDLDFETAVEIYREAAGIGIRAGVDLVLIETMSDSYELKAAVLGVKEAADLPVFATTIFDKGKLLTGGTPRTVIALLEGLGVDAVG
INCGLGPVQMKEFVREFAKYASVPIIVNPNAGLPRS-VEGRTVYDIDEDQFAKTMAEIVDMGASVVGGCCGTTPEYIRKLCLACREKKQKLPSK--KAET
VVTSYSQLVEIAS--DPVIIGERINPTGKPKFKQALRDHDMEYILREGLAQQDSGAQVLDVNVGLPEIDEPSMMEEAVRELQSILDLPLQIDTSNIEAME
RAMRIYNGKPLINSVNGKAESMDAIFPLVKKYGGVVVALTLDEEGIPDTADGRIRVAEKIYRRAAQYGIDKKDILIDTLCMTISSDSQGALTTLEAVRRI
RDELHGKTILGVSNVSFGLPQRESINAAFFTMAMMNGLSAAIINPNSDAMMRSWRSFRALAALDENCGDYISAYGGQTKQ------QPSDTV--FGSQVQ
LWESVVRGLKEQAARAAAAALKEA-SPLEVINACMIPALDCVGKGFEQGTVFLPQLLMSAEAAKAAFEVLKAAMAGSGNQEKKGVIILATVRGDIHDIGK
NIVKVLLENYSYEVVDLGKDVPPERIAEETVKHRAPLVGLSALMTTTVPSMEETIRLLRKEAGWAKIMVGGAVLTPEYADSIGADAYCKDAMASVNYAQK
VIG
>tr|E9SQA3|E9SQA3_CLOSY Putative uncharacterized protein OX=742741 OS=Clostridium symbiosum WAL-14673. GN=HMPREF9475_02499 PE=4 SV=1
-M-ILEELRE-KILLFDGGTGSLLQEAGLKPGELPETWNISHPDIVVKLHSDYLEAGCDIIKTNTFGANRFKYNSQYSLKEIVTAAMDNAKCAVKK-GYI
ALDIGPTGKLLKPMGQLDFEEAVSVFREVAETGAEQGADLILIETMSDTYELKAAVLAAKESSSLPVFATVIFDKGKMLTGGTPQTAIALLEGLGVDAVG
MNCGLGPVQMKPLAAEFIKYASVPVIVNPNAGLPRS-EGGRTVYDIGPDEFEQAMEEILDMGISVAGGCCGTTPGHIRRLNRLRAGRRQKLPQE--KQST
VITSYAAAVEIGD--DPVIIGERINPTGKSKFKQALRDHDLEFILREGISQQERGAHVLDVNVGLPEIDEPSMMAEVIRELQGITELPLQIDTSNTEAMA
RAMRVYNGKPLLNSVNGKQEVMDAVFPLVKRYGAVVVALTLDESGIPETADGRIAIAEKIYREAAKYGIGKKDILIDALCMTISSDRLGALTTLETVKRV
RQEMGGRTILGVSNISFGLPVRENINANFFTLALYNGLNAAIINPGSEAMMCSYHSFRALAALDENCGSYIEAYKNAAAS------SAAGSG--SPGEAP
AWDSVEKGLREQAAQSAKQLLAEK-EPLDVINTCMIPALDHVGKGFEAGTVFLPQLLMSAEAAKAAFDVIKEKMAESGQREKKGKIILATVKGDIHDIGK
NIVRVLLENYSYDVLDLGKDVAPEQIVREAVKQHVPLVGLSALMTTTVPAMEETIQRLRQEAPWTKIMVGGAVLTPEYAKTIGADTYCSDAMASVSYAQK
IIG
>tr|G2SXJ6|G2SXJ6_ROSHA 5-methyltetrahydrofolate--homocysteine methyltransferase OX=585394 OS=Roseburia hominis (strain DSM 16839 / NCIMB 14029 / A2-183). GN= PE=4 SV=1
-MEFATLVGS-RPVILDGATGTNLQKAGMPVGVCPEQWILENPGVLIELQERYVEAGTDILFAPTFTASRIKLEEGLSLVQMNRELVALSKRAAG-RAYV
AGDLTMTGRQLYPLGDLMFEDLVEVYKEQAKVICEAGADLFVVETMMSLQECRAAVIAIREVCDLPIMVSLTYNDGRTLYGTDPATAVIVLQSLGADAVG
LNCSTGPEAMIDPVQQMAEYATIPLLAKPNAGMPEL-CDGVTVYRTTPEEFASVGAKLVEAGAAIIGGCCGTTPEHICALKQAVGSMPVHMPLT--KKRR
MLASERMHVEIRLDGKFMVIGERINPTGKKKLQAELKEGSLSMVRTMATEQEENGAQILDINMGMNGIDEKQMMLDAIYEVTSTVDLPLCIDSSHVDIIE
AALRIYPGRALVNSISLEKEKIEYLLPIAKKYGAMFILLPLSDEGLPKDSAEKHGIIREILRRAEAIGMGKEDIVVDGLVATIGANPKAALECFETFSFC
KNEMELPTVCGLSNISFGLPERSYVNTAFLTMAIGNGLTMAIANPSQELLMNAAFASDMLLNKEESGIRYIGRMSEVAVK-----GTAAGQA--GNGGAS
VFTAVLKGNKNHILDEVKHALDTGEKPDDIINGHLIPAINEVGELFDKQKYFLPQLISSANTMKVAIEYLEPMLARSDK-EPKATLVVATVEGDIHDIGK
NLVVLMLKNYGYHVIDLGKDVPADLIVDTAMKENARVIGLSALMTTTMMRMKDVVELVKERGCTAKVVIGGAAITESFAEEIGADGYSKDAAECVKLVDR
LLE
>tr|D7GVK6|D7GVK6_9FIRM B12 binding domain./Pterin binding enzyme./Homocysteine S-methyltransferase OX=245014 OS=butyrate-producing bacterium SS3/4. GN=CK3_22670 PE=4 SV=1
-M-ILELMKE-RRIYFDGGMGSLLQARGLKPGELPETWNLSRPEIITEIHREYLDAGSDVVTTNTFGANHFKFKAGYSVKEIVTAAVRNAKNAIAA-GYA
ALDMGPTGKLLKPYGDLEFEDAYEAYKEVVLIGKAAGADLVIIETMGDGYELKAAVLAAKENSDLPVFATVTLDKGKMLTGGNVESVTALLEGLGADVIG
LNCGLGPIQLLPFMRDMAKVSSTPILVNPNAGLPRS-EGGKTVYDIDADEFATAMQEMARNGATVLGGCCGTTPEHIHKTKLVCDDIPVCEITD--KNRT
VISSYSHAVTFGG--RPILIGERINPTGKPKFKQALKDKDLTYILSMGVAQQESRADVLDVNVGLPGIDEPQMMVDVVKELQGVLDLPLQIDTSDPVAME
RALRIYNGKPLINSVNGKKEVMEQIFPLVKHYGGVVVALALDENGIPETADGRLAVARKIYETAASYGIPKKDILVDCLCMAVSSDKNGALTTLETVRRV
RDELGGKTVLGVSNVSFGLPMRENINSSFFLLAMQNGLSAGIVNPNLEAMMQAYDSFLVLSAQDENCAGYVGIYGPKEAEKK--RQKAAAVN--QAGGAA
LKKSIVKGMSQAAADAAKLALKDT-DALELINTDMIPALDEVGKGFEAGTVFLPQLLMSAEAAKAAFAVVKESMEASGEQEKKGKVILATVKGDIHDIGK
NIVKVLLENYSFDVMDLGRDVPPETIVEAAVKEHVPVVGLSALMTTTVPAMEDTIKALRKDAPWVKVMVGGAVLTQEYADAIGADTYCKDAMASVNFATS
VIG
>tr|F3AQN4|F3AQN4_9FIRM Putative uncharacterized protein OX=665950 OS=Lachnospiraceae bacterium 3_1_46FAA. GN=HMPREF1025_00038 PE=4 SV=1
-M-IRQRLGK-DLLFFDGGMGTLLQEKGLAPGELPETWNLTHSEEIYKIHRQYIEAGSDIILTNTFGANALKFHDSCSLEEIIKAAVSHVKKAEREKIYT
ALDVGPTGKLLKPMGDLEFETAYEAFKEVVILGEQAGADLIHIETMSDTYELKAAVLAAKENTSLPVFATVIFDRKKLLTGADVSSVVALLEGLGVDALG
INCAMGPKEMLPVLEELIKYSSVPIIVKPNAGLPKQ-RDGKTYYDVTEDEFAAYMEQIVRMGACVIGGCCGTTPEHIRAMRKRCENAELVPVTE--KEFT
VVSSYGQSVILGE--GSKIIGERINPTGKKRFKQALKEHDLDYILREGITQQDQGAHILDVNVGLPDIDEPALMEEVVQELQSVVNIPLQIDTVDEKAME
KALRIYNGKAMVNSVSGKKESMEKVFPLVKKYGGVVIGLTLDEDGIPADADGRVRIAEKIIKTAEKFGIKKKDIVIDALAMTISSEPEGAKVTLETLRRL
RDEIGVNTVLGVSNISFGLPCRPIVNAAFYTMAMLNGLSAGIINPSSEDMMKSWYAYHALMNLDNNCEQYIQKYANSVVS------TNIMKT--SESKMT
LQEAIEKGLRDDAGKITTDMIATE-APLDIINEELIPALNHVGDGFEKGTVFLPQLLMSAEAAKSAFSVLKEKMEKSGEREKKGRVILATVKGDIHDIGK
NIVKVLLENYSFDVIDLGKDVSPEKIVETACEKQVPLVGLSALMTTTVVSMEETIKMLREKKPDCKVMVGGAVLNQEYADMIGADFYGKDAMQSVHYAEK
IFK
>tr|A5Z3E1|A5Z3E1_9FIRM Putative 5-methyltetrahydrofolate--homocysteine methyltransferase OX=411463 OS=Eubacterium ventriosum ATCC 27560. GN= PE=4 SV=1
-VANKNIFK--DFILLDGAMGTMLQQKGMELGTVPETLNITKPDWIIDIHKQYIDAGSDVVYANTFGANRYKMANGYSVDELIGAAINNAKEAAKG-TLV
ALDMGPIGQLLEPTGSLSFEEAYDIFKEEVIAGRNAGADIIVIETMTDLMETKAAILAAKENSDLQVMCTMTFENKRTFTGCSVSAMCLTVQGLGVDALG
VNCSLGPKELMPIVEEISKWTTVPIVVKANAGLPDP-VTN--TYNVLPDEFADTCKEMVKYGAKVLGGCCGTTPAYVAKLKEMVVNASVVKKK---PRQL
AVCTPLKTVVVD---QPRIVGERINPTGKKRFKQALRDNDMNYILSQAIEQIDAGADILDVNVGSPDIDEKEMMVKVIKALQAIVDVPLQIDSTKPEVLE
AALRVYNGKPIVNSVNGEEEVLDTILPIVAKYGGAVIGLALDENGIPPTAEGRVEIAKRIRDKAMSYGIPKEDIIIDCLTLTVSAEQKAAAETLKAMNIV
KNELGLRTVLGVSNISFGLPNREIINKTFLTIAMANGLDLPIINPNVPSMVWAVKAYKVLAAIDENSMDFIDYSSKTKTE-----VVKSNDS--T-VSL-
ILKAMETGMKDDGRSYTSQLLKEK-EAMEIINQILIPALDVVGDKFEKGTIFLPQLILAADVAKECFDEIKNYLADSGSSESKGKIIVATVKGDIHDIGK
NIVKVILENYGYNVIDLGRDVDCMEVVNAAIENDVHLVGLSALMTTTLGSMEETIKLLREHNVDCKIMVGGAVLTEDYAMKIGADYYAKDAKMSADIAKK
VLG
>tr|I5ATD5|I5ATD5_EUBCE Homocysteine S-methyltransferase OX=633697 OS=Eubacterium cellulosolvens 6. GN=EubceDRAFT1_1242 PE=4 SV=1
-MEFKELLDR-GFVFLDGATGTNLQNAGMPTGVCPEQWILENREIMVQLQKDFVDAGTQILYAPTFTANRLKLGDGLRLRQMNIDLVAISKEAA--RALV
AGDMTMTGRQLYPMGTMMFEELVDIYKEQAEALVAGGCDLFVIETMMSLQETRAAVLAIREICDLPIIASLTFEDGRTLFGTNPEAAMITLQSLGADVVG
MNCSTGPDGMIENIEKMYSVANVPVLAKPNAGLPQI-DDGRTFYPTSPEEFAAEGRKLIEAGARVLGGCCGATPEHIRKLVEMAGTMEPKPVHT--EKKR
LLSSERSFVEITLDGMLQIIGERINPTGKKKLQAELREGSLDLVRDFARMQEEDGAEILDVNMGTNGIDEKEMMIKAVYEVTQVSDCPLCIDSSFPEVIE
EALRIYPGRALINSISWETEKFERLIPIAKKYGAMFVFLPVSDEGIPATQEEKHAIIHAALEECRKRGIDKEDMIVDGLVATVGADPEAALHCTDTFAHC
KNDLGLATVCGLSNISFGLPERSFVNMAFLVMAIKSGLTLAIANPSQELLMNAAAATDMLLAREGSDIKYITRAKEPAAQ-----AGGGASA--GKEGSN
VYKAVMNGEKTKIIKLCETELSLGTKPDDIISLYLIPAINDVGDLFDKQKYFLPQLIASAGTMEKAIAHLEPMIEKKEGSGPVETVVIATVEGDVHDIGK
NLVALMLRNYGYRVIDLGKDVPAETIIRSALEENASVVGLSALMTTTMMRMKDVVEEAAAKGYKGKIIIGGAAVTSSFAEEIGADGYSRDAAECVQLVKK
LLA
>tr|G0VS27|G0VS27_MEGEL Homocysteine S-methyltransferase OX=1064535 OS=Megasphaera elsdenii DSM 20460. GN=MELS_1849 PE=4 SV=1
-MEFQHLLSR-GVVMLDGATGTNLQQAGMPIGVCPEKWILENRQVMIDLQRHFVEAGSQILYAPTFTGNRIKLAEGLQLAAINQGLVAISKEAA--KALV
AGDMTMTGQQLYPMGDLTFEELVDVYRQQAKVLYDAGVDLFIVETMMSLQETRACVLAIKEVCDLPIMATLTFEDGRTLYGTPPEAAVVVLQHLGVAAVG
LNCSTGPADMVETVQKMYEYATVPLIAKPNAGLPEW-DGDKTVYKTTPEEFAQDGKLLIEAGAHIVGGCCGTTPDHIRALHDAVCQMTPKAPHA--SHHR
VLASERQVVEIQLDGSFQVIGERINPTGKKKLQAELRAGKLDLVRAMAREQERNGAAILDVNMGTNGIDEKEMMLKAIYEVTGVSGLPLSIDTSSPEIME
AALRIYPGRALVNSISCETEKRKQLLPVVKKYGAMFIALPVSDAGIPKTLEEKHAVLDELLTDAYDHGFTPEDVVVDALVATVGAAPTSALDCMATFSHC
KRDLGLATVCGLSNISFGLPDRMYVNATFLGMAIASGLTMAIANPSQDLLMNTAAAANMLMNKEGSDLAYIHRMDKQLAR-----QGMPADV--AAGESN
VYQAVLEGEKDAVVSLAQAELAKGMAPDAVINDLLIPAITKVGDLYDKQVYFLPQLIASANTMETAIAYLEPLIKKEPGQQDMATIVIATVEGDVHDIGK
NLVGLMLRNYGYKVVDLGKDVPAGTIIETALREKASVVGLSALMTTTMMHMKDVIAEAADKHYDGKIIIGGAAVTPSFSDEIGADGYSKDAADCVKLVGR
LLA
>tr|F7JI91|F7JI91_9FIRM Putative uncharacterized protein OX=658655 OS=Lachnospiraceae bacterium 1_4_56FAA. GN=HMPREF0988_00045 PE=4 SV=1
-M-IREDLRE-KRLFFDGGMGTLLQEKGLKAGELPEIWNLEHSEEVISIHQAYIEAGSDIILTNTFGANALKFHDVYSLEEITKTAVAHGKEAVRRNVYV
ALDVGPTGKLLKPMGDLAFEEAYEAFREVMQYGEEAGADLIHIETMSDTYEIKAAVLAAKENTNLPVFVTAVFDRKKLLTGADVPAFVSLLEGLRVDALG
INCGMGPEQMIPILEELQRYSSTPVIVKPNAGLPKQ-RDGETVFDVEPDAFAQTMRKIAGSGAAVIGGCCGTTPEHIRAMTAVCLEIPYEPAGK--KNLT
MVSSYGKTVIFGE--ESKIIGERINPTGKKKFKQALVERDMDYILREGIRQEDNGAHILDVNVGLPDIDEVSMMKEAVTALQGVTSLPLQIDTVDPRAME
EALRVYNGKPMVNSVSGKQESMDAVFPLIQKYGGVVVGLTLDETGIPETADGRVEIAERILKEAEKYGIEKKDIVIDVLAMTVSSEPQGAIVTLEALRRV
RRELGVHTVLGVSNISFGLPFRPVINANFYTLALYNGLSAGIINPSSEDMMQSYDAYHALMGLDENCSRYVAKYGAKAAA------QKEAAQ--RESELT
LKTAIERGLKEEAPQMADALLKTE-QPLEIINTYLIPALDHVGKGFEEGTVFLPQLLMSADAAKAAFEVLKAKIASEESTEKKEKIILATVKGDIHDIGK
NIVKVLLENYSFDVIDLGKDVAPELILQTAKEQEVRLVGLSALMTTTVASMEETIRLLKKELPECKIMVGGAVLNQEYADMIGADFYGKDAMKSVYYAQE
LLK
>tr|C0EVI8|C0EVI8_9FIRM Putative 5-methyltetrahydrofolate--homocysteine methyltransferase OX=411469 OS=Eubacterium hallii DSM 3353. GN= PE=4 SV=1
-MELYTMIQQ-KPVILDGATGSNLQKVGMKPGVCPEEWILENEDKLIDLQKSFVEAGTNILYAPTFSGNRVKLEEGLRAEEINKRLVGLSKRAAGDKALV
AGDMTMTGVALEPVGPMKLEALINIYKEQAKYLLEAGVDLFVVETMMSLAETRAAVIAIKEVCNLPVIASLTFQDGRTLYGTDPVTAVVVLQSIGADIIG
VNCSTGPGEMIPVIKKMKEYAEVPILAKPNAGLPVL-EDGVTVYPMTPEEFASWGPAFIEAGAGLIGGCCGSTPEHIRMLTEKVSGLTTKAPCN--IHPI
MLASERKSQEIALDGKFLVIGERINPTGKKKLQEELRAGKLDLVEEMAEQQEEMGAHILDINMGTNGIDEKEMMLKAISKVTMVSSLPLCIDTSYVEVME
AALRAYPGRALINSISLETEKIEKLLPLAKKYGAMFILLPLSDEGLPKSLAEKKEIINTILEKAKKLGVSKNQIIVDGLVTTVGANKNAALETLETIRYC
KEDLKLCTTMGLSNISFGLPERPYVNGAFASMAIASGLTMAIANPSNQLLMGISFASDLLRNKEGSDIAYIEQIEPANGE-----KQPNEKN--AAGEAN
VFEAVLKGNKDGIVDVVKKELSKGTKPGEILDGLLIPAINEVGVLFDKQKYFLPQLISSANTMEQAVEYLEPLLKEGGIQEKMPTIIIATVEGDIHDIGK
NLVALMLRNYGYDVIDLGKDVPADEIIAAAKEHNASIIVLSALMTTTMMRMKDTIALKEKEHLDVKVMIGGAVTTQSFADEIGADGYSADAADAVRLAKK
LLA
>tr|E0S281|E0S281_BUTPB Methionine synthase MetH OX=515622 OS=(Clostridium proteoclasticum). GN= PE=4 SV=1
-MEFWGLSNN-RILFLDGATGTNLMKAGMPAGVCPENWILEHQDVMINLQSNYAKAGADIIYAPTFTGNRIKLADGLRIEEINSSLVKLTKKAAPG-VLV
AGDITMTGRQLRPIGDLDFEELVDVYKQQIKILEAAGCDILVVETMMSLQECRAALIAAKEVTDLAVMVTLTFEDGRTLYGSDAASSAITLEALGACAIG
ANCSTGPDKMAAIISDMAAVTSIPIIAKPNAGLPSVDENGNTEYDMDCDTFVKEMELLVSAGASIIGGCCGTTPDYIKGLKDRYGNV---KPND--IRRR
YLASERMSLSFGLDENFMIVGERINPTGKKKLQEQLREGNLDMVCDFAANQEKEGASILDINVGMSGIDEKEMMLKVMEEVMSITDLPLCIDTSSAEVME
AALRLYPGRALMNSISLEKGKAEKFLPLAKKYGAMFILLPLAEA-LPKDSQEKIDNINTIYEMATKLGMNKEDIVVDGLVATVGADPNAAINTLDTIGYC
HEN-SYATICGLSNISFGLPQRSNVNTAFLTMAIARGLTMAIANPSQEMLVNAAFASDLLRKKEGADVRYITRMAD-QNS-----ANSAAQN--VSSKAD
IKKDVLTGNKRGIVKDTEKAVKEGNSPRQILDEILMPAINEVGDLFDKGKYFLPQLIAGAEAMKLSIGYLEPLLKEGADSEKLPSIVIATVHGDIHDIGK
NLVALMLKNYGFNVIDLGKDVPREEIIKAARKYDAKIIALSALMTTTMKEMKNVVDLAHAENLDAKIIIGGAVVTQDYADEIGADGYSSDAADAVRVVKN
ILG
>tr|G5HD15|G5HD15_9CLOT Putative uncharacterized protein OX=742733 OS=Clostridium citroniae WAL-17108. GN=HMPREF9469_00477 PE=4 SV=1
-M-LLEEMKV-RRLFCDGGMGSMLQARGLQAGEMPEMWNLTHPEIVRDIHRQYLKAGADIMETNTFGANGLKYKD--NLEEIITAAVGHAKAAVEE-GYV
ALDVGPTGKLLKPLGDLDFEDAVSLYKEVVAYGVKAGADLVFIATMSDSYELKAAVLAAKEAENIPVFTSVTFDKGKLLTGGNVESTVALLEGLRVDALG
INCGLGPEQMKGILKDILEVTSLPVMVNPNAGLPRS-ENGKTVYDINEDQFAQVMREIVDMGAAVVGGCCGTTPDHIRETVKLCKDIPVRWPEK--KRRT
VISSYAQAVVVDR--KTVIIGERINPTGKSKFKQALRDHNLEYILREGVSQQDNGADVLDVNVGLPEIDEPSMMEEVVKELQSIIDLPLQIDTSNIEAME
RAMRVYNGKPLINSVNGKAEVMSQVFPLVAKYGGVVVGLCLDEGGIPETAEGRIAVGRKIIDTAADYGIGPEDIILDGLCMTVSSDSRGALTTLETLRRI
RDELGGKSVLGVSNISFGLPQREIINGAFFTMAMEAGLNAAIINPNSEAMMRAFYSFNALMDRDPQCGRYISIYSGQASG------LGRTIG--KNGGAL
LTSAIERGLKDAAHQAVGVLLEKR-DALDIINDHMIPALDRVGKGFEKGTVFLPQLLMSAEAAKAAFEVIKTRMDQSGQQEKKGTVILATVKGDIHDIGK
NIVKVLLENYGYDVMDLGKDVPPERIVEEAVKGKVPLVGLSALMTTTVPSMEETIQKLRATAPNVKVMVGGAVLTKEYAQTIGADMYCRDAMASVNYAES
IFV
>tr|B8CZI7|B8CZI7_HALOH Homocysteine S-methyltransferase OX=373903 OS=Halothermothrix orenii (strain H 168 / OCM 544 / DSM 9562). GN= PE=4 SV=1
-MDFTSTLQE-KIIIGDGAMGTMLQACGLSSGHAPESWVIKKPDTIYKIHKEYVAAGAGLIETNTFGANRLKLKSGLKIEEINVKATGLARKAA--KVFV
AGSVGPTGKLMEPHGDLSFDRARDVFKEQISYLVHAGVDVVIIETMSDLKELRAAVVAAKEF-NVPVIAQMTFTRGITLTGSPPEVVAIVLDKMGVDVIG
VNCVAGIEEALIVIKKMSRVTSKPLSVFPNAGLPES-KGGETVYPQTPDAFTDKIPELLKYNVKLIGGCCGTNPRFIKGIKQVVYEAKVSNTNEN-KNRT
YLTSNHTYLQASEDKPVFLIGERINPTGRNDLKEALKGEKWSVLRKEAREQVIAGAHLLDVNIGMAGIDREKCMKKVIQELQLEVDVPLVIDTPRTGVLE
TALKEYTGRALINSVNGNPDVMDKVFPLACRYGAAVIGLTLDDRGIPSEVEGRLEIARQIIARAREYGLGEEDIIIDPIVLTAGSNQSEVMKGIETLKRI
KEELGVKTTMGISNVSHGLPNRKLINRTFLAMALGAGLDFPIVDPVDEDLMATVRAANLLTARDRNGQNFLKWYGNRDNN-----KETKSSD--KEDRLS
IADIVVSGDTDIIEEQVARALELY-QPREIINRAMVKGLKRVGDLYDRGEYFLPQLMQSSRVVKKAFDLLKERMNSKGEN-KAGRILLATVEGDIHDIGK
NIVKVVFNNYGFEVVDLGVNVKSDDIVEAAFDHKVDIVGLSALMTVTMEKMRETVNILKQKGFKGGIIIGGAVTSEDFAREIGADLYAGDALDGVRKVKK
YLN
>tr|F5RLH7|F5RLH7_9FIRM Vitamin B12-dependent methionine synthase OX=888060 OS=Centipeda periodontii DSM 2778. GN=HMPREF9081_1113 PE=4 SV=1
---MPGRGMS-DIIILDGGMGTQLQARGLAPGERPELFGLDHPEVIEEIHRNYIAAGSRVIYSNTFGANGHKLEGGKSVAEVIEENVRTARRAGENSVRV
ALDIGPIGELVEPLGTLSFEDAYELFREMVVAGAEAGADLVIFETLTDLYEVKAAVLAAKEHTQLPIWVTMTFENGRTFLGAAVPSVAVTLDALGVAALG
VNCSLGPVELLPIVDALMEWTDLPIIVKPNAGLPDP-RTG--AYEMTAEDFGREMAEFARRGAVIMGGCCGTTPDFIRALSASVAAGAAERPVR--KKRK
GIASPARVAEYG---KLNVIGERINPTGKKRLQQALLEEDYGYIKKLAISQQEAGAQVLDINVGAQGVDEEKIIPYVVKAVQSVVDLPLQIDSANPRVIE
AALRVTNGRVIINSVSGERERMDAIFPLAKHYGAAVLGLAMDEKGLPETAAERVAIAERIVAEAEKYGLDREDIIIDCLTLTVSAQQEQAMETLRAVREV
HERLGLHCALGVSNISFGLPARGHMTENFLIQAMHVGLDFPIINPNTKGVMDAVVSFRAVSGEDVDCAAYIERFAPRKEL-----GITGDES--A-GAVQ
LMDAIIRGLSDDAERITRKLLTEM-APMEIIQEKVIPALDIVGDRYEKEIIFLPQLINAANAATAGLELIKVRLAEEGQGVSKGKIILATVEGDIHDIGK
NIVKVVLENYGYQIIDLGRDVPVTRVVEVAIEKKVGLIGLSALMTTTVTAMKRTIDALHEAGHPCETVVGGAVLTEDYAKEIGADYYAGDARSIVEIARR
VLG
>tr|H1HS00|H1HS00_9FIRM Methionine synthase OX=796942 OS=Stomatobaculum longum. GN= PE=4 SV=1
-R-LRACLGK-EWLYCDGGTGSLLQEKGLKGGELPERWNLERPEDVIEIAESYFRAGADIVNTNTFGANRLHYPD--ELEQIVRAGVRHVREGLSRTGFV
ALDLGPTGRLLKPMGDLEFETCVEIFAEVVRWGKEEGADLVLIETMSDAMEAKAAVLAAKENSDLPVFVTVVFDKGKTLTGGTVESVTAMLEGLRIDALG
VNCGLGPVQLYPIVKALTEVCSIPIVVNPNAGLPHA-KDGKTYYDLSAEEFSDEMKKIASLGVQVLGGCCGTTPEHIRLEIQKTGELPFCEPVK--KHRA
VVSSFSQTVVLGK--RPIIIGERINPTGKKRFKEALRNGDIEYILEQGIEQEDAGADMLDVNVGLPELNEPDMMETVMTRLQGVTALPLQLDTTNLEALE
RGLRLYHGKAMINSVNGKEESLETVLPLVAKYGGVVVGLALDEGGIPEDAEGRIRVAKKIYARAAAYGIPPEDIIIDGLAMTISTDDNSANVTLEVLRRV
RDELHGHSILGVSNISFGLPQRELINSFFFALAMKSGLSCAIINPNNEAMMAAYRSYLALSGFDRQCQGYIAEYAGKANV-----FKGKVVV--TAG--P
LIDAIRFGLGEKATEETKRRIEGE-APLDIVNRELIPALDVVGKGFEKGTLFLPQLLMSAEAAKAAFEVIKSAMS--GTRKERGSVILATVKGDIHDIGK
NIVKVLMENYGYKVYDLGRDVPAETIVETAVAHDVKLIGLSALMTTTVVNMEDAIKLIRERKPDAKVVVGGAVMTKEYADDIGADCYAKEAMDTVRYADT
LFP
>tr|G5I3H8|G5I3H8_9CLOT Putative uncharacterized protein OX=742735 OS=Clostridium clostridioforme 2_1_49FAA. GN=HMPREF9467_03311 PE=4 SV=1
-M-ILEEMKV-RRLFCDGGMGSLLQARGLKPGELPERWNLTHRDVLISIHRSYLEAGADIMTTNTFGANGLKFKE--DLEPIVTAAVENARTAVKE-GYV
ALDLGPTGRLLKPLGDLEFEDAVKLYKEVVSIGARAGADLVLIETMSDSYELKAAVLAAREAERLPVFATVIFDKGKLLTGGNVESTVALLEGLRVDALG
INCGLGPVQMKGILEEILRVSSLPVLVNPNAGLPRS-ENGKTVYDIDAEGFALVMEEIVTMGAVVVGGCCGTTPEHIRLMTRRCKDMPVVWPEK--KHRT
VVSSYAKAVTVGG--KTIIIGERINPTGKSKFKQALRDHNLEYILKEGVSQQDNGADVLDVNVGLPEIHEPSMMEEAVRELQAIIDLPLQIDTSDMEAME
RAMRIYNGKPLINSVNGKEESMTRVFPLMAKYGGVAVGLCLDESGIPDTAEGRLAVGRKIIDRAAEYGIGPEDIILDGLCMTVSSDSKGALTTLETLRRI
RDELGVGTVLGVSNISFGLPQREIINAAFFTMAMECGLGAAIINPNSEAMMRAYYSFNALMDLDPQCGQYISVYSGQSAG------LGQTIG--RGGGPA
LSAAIERGLKEAAHNAVSALLKER-EPLDIINSEMIPALDRVGKGFEKGTVFLPQLLMSAEAAKAAFEVIKAAMDGSGQQEKKGTIILATVKGDIHDIGK
NIVKVLLENYSYEVIDLGRDVPPEAIVKEAVERQVALVGLSALMTTTVPSMEETIRQLRAASATVKVMVGGAVLTEDYARTIGADAYCRDAMASVNYAEQ
IFG
>tr|D6E430|D6E430_9FIRM Methionine synthase (B12-dependent) OX=657318 OS=Eubacterium rectale DSM 17629. GN=EUR_10190 PE=4 SV=1
-MEFRKYIRE-NIVILDGATGTNLMAAGMPVGVCPEKWVMEHPQVILDLQKAYVDNGTNIVYAPTFTGNRIKLLEGLKINEINTTLVGLSKQAVGDRALV
AADMTMTGRQLFPLGDLMFEELLEVYKEQARILDAAGADVFVVETMMSLQECRAAVLAIKEVSDLPIMVTLTYNDGRTLFGTPPETAVVVLQSLGVDAIG
VNCSTGPTEMIALVEKMAEYSTVPLIAKPNAGLPEL-EDGKTVYKMTPDMFADAMRGLVEAGASIVGGCCGTTPEHIRALTEAVKSMPVHKPLE--HHRR
VLASERKNVEIDLDGNFTVVGERINPTGKKKLQAQLREGKLDLVRQMAMEQETNGARILDINMGMNGIDEKEMMKSVIYEVSSTVDCPLCIDSSYVEVIE
EALKIYPGRALINSISLETEKMEKLLPLAAKYGAMFILLPLSDAGLPKDVEEKKQIINTIYDKALSLGMAHEDIVVDGLVATIGANPKAAIECYETIAYC
KDEKKLPTICGLSNISFGLPERMYVNTAFLTMAICKGLTMAIANPSQELLMNAAFASDMLLDRPDSDIAYIERMAEVVVK-----KSDNAAS--ASGTCD
VFQAVLKGNKGSIIDEVKKMLSDGAKPDEIINNSLIPAINEVGELFNQKKYFLPQLIGSANTMKLAIEHLEPLLEKKDSGDDMPTLVIATVEGDIHDIGK
NLVVLMLKNYGYNVIDMGKDVPCEDIVNKAIETNAAVIGLSALMTTTMMRMKDVVEICKEKGCKSKVVIGGACITQSFADEIGADGYSKDAAECVKLVER
LLN
>tr|D4KZF5|D4KZF5_9FIRM Methionine synthase (B12-dependent) OX=718255 OS=Roseburia intestinalis XB6B4. GN=RO1_22390 PE=4 SV=1
-MAFRELVKK-GPVLLDGATGTNLQKAGMPVGVCPEQWILENSEVLIDLQKRYVEAGTDILFAPTFTASRIKLKEGLHLEEMNRKLVALSKEAAGTNALV
AGDLTMTGEQLYPLGDLMFEDLVDVYKEQAKIIAEAGADLFVVETMMSLQECRAAVLAIREVCDLPVMVSLTYNDGRTLYGTDPVTAVVVMQSLGADAVG
MNCSTGPEAMLEPIAKMAEYATIPLLAKPNAGMPEL-IDGQTVFNVEPEEFAEVGKKLVEEGAAIIGGCCGTTPEHIRALKEAVKGIPVKAPLQ--TKRR
MLTSERKSVEITLDGRFMVIGERINPTGKKKLQAELKEGSLNLVRTMALEQEENGASILDINMGMNGIDEKEMMLRTIYEVTSTVDCPLCIDSSHVDIIE
AALRIYPGRALINSISLEKEKFEKLLPIAKKYGAMFILLPLSDEGLPKDSAEKHGIIRTIMDEAVRIGMAKEDIIVDGLVATIGANPNAALECFETFSYC
KNELELPTACGLSNISFGLPERTYVNTAFLTMAIANGLTMAIANPSQELLINAAFASDMLLNKKESDIRYIERMSEVMVQ-----KTPAGTS--AAGEIS
VFQAVLKGNKEHVLEEVKKMLDGGAKPDEIINEHLIAAINEVGELFDKKKYFLPQLISSANTMKLAIEYLEPMLERSNT-EAMATIVVATVEGDIHDIGK
NLVVLMLKNYGYHVIDLGKDVPADVIVDTAMNEGAKVIGLSALMTTTMMRMKDVVELAKEKGCTAKIVIGGAAITESFSDEIGADGYSKDAAECVKLVER
LLA
>tr|G7MD30|G7MD30_9CLOT Methionine synthase OX=641107 OS=Clostridium sp. DL-VIII. GN=CDLVIII_2252 PE=4 SV=1
-VGLKEYIKD-NILIFDGAMGTMLQKKGLKLGENPELLNIKEPYIIEEIHKEYINSGANVITTNTFGANELKLKLNLEVEDAVDAAVKIAKRAKGD-TYI
ALDIGPIGELLEPMGTLGFDRAYEIFKRQVIQGTKSGVDIILIETMTDLYELKAAILAAKENSDLPVFCTMTFENLRTFTGCSPEAMVLVLEGLGVDALG
VNCSLGPKQLKPVIEEICSIAHIPVMVQPNAGLPTL-SIGETRYDVTKEEFADTLCGFIDSGVRIIGGCCGTTPEYIKELSNTVKEKKIIPITR--EHYA
AICTPSKVVRID---GVRIIGERINPTGKKIFKEALKNGDLDYILSQAVSQIEAGAHILDVNVGLPEIDEPSMMHKVIKEIQGIIDTPLQIDSSDHKAIE
TGLRYYNGKPILNSVNGEDAVLDKILPLVKKYGASVVGLTLDERGIPAKAEERFEIAKKIINKAAEYGIKKEDVFIDCLVLTVSAQQEEVQETLKAVRMV
KEKLGVKTVLGVSNISFGLPNRELINETFLALALANGLDLPIINPNAKGMTRVIDSYNVLYNYDKGAESYINNYANTKNN-----LSANSNA--N-TDHD
LKYIVIKGLKEEAKQATIELLKSK-KELEIVNEYLIPALDEVGSKYEKGELFLPQLIQSAETVKNAFSILKTEIAKSNKSISKGKIIVATVKGDIHDIGK
NIVKVILENYGYEMIDLGKDVPIKTVVEEAKNHEVSLIGLSALMTTTLKSMEETIKALREDGYNGKIFVGGAVLTKDTAERIGADFYAKDAKESVEIARK
VLL
>tr|F9MNC8|F9MNC8_9FIRM Putative methionine synthase OX=1000569 OS=Megasphaera sp. UPII 135-E. GN=HMPREF1040_1253 PE=4 SV=1
-MEFHAWLKE-GILFLDGATGTNLQAAGMPVGVCPEAWILENKQTIIALQQQFVQAGTDILYAPTFTGNRIKLAEGLKIVEINTQLVSFSKEAA--NAKV
AGDMTMTGQQLYPLGELTFEELVDVYREQAQILYDAGVDLFVVETMMSLQETRACVLAIRECCDLPIMASLTFEDGRTLYGTPPEVAVVVLQAMGVDAVG
LNCSTGPEDMVEIVKTMHAYASIPILAKPNAGLPEL-EQGHTVYKTTPEVFAEAGTALVHAGARIIGGCCGTTPEHIKALKEAMKHLSPLPYKA--EHRR
IVTSERKIQEIDLHGSFCVIGERINPTGKKKLQEELRAGSLRLVRTMAREQEERGAAILDINMGTNGIDEKDMMVRAIYEVTSVTGLPLCIDSSYPEVLE
AALRIYPGRALINSISLETDKIKQVLPLAKKYGAMFIALPVSDEGIPQTIEEKHAIIEQIVEKAKEFHLTEADIVVDGLVATAGATPTAALDCLATFTYC
KKR-NLATVCGLSNISFGLPQRTYVNMTFLAMAISGGLNLAIANPSQDMLMNVAAAANMLMHRPESDIAYIKQIEK-IKR-----TQITNTT--STESAN
VYRAVLEGEKDEIVSFAQEELNKGMKPEDIINHLLIPAINEVGELYNKQLYFLPQLIASANTMEQAISFLEPQIKRASNKMAMPTIVIATVEGDVHDIGK
NLVGLMLRNYGYHVIDLGKDVPAETILDTALKEHAAIIGLSALMTTTMMRMKDVVLLAKEKAYTGKIIIGGAAVTPSFAEEIGADGYSKDAADCVKLVNT
LLA
>tr|C9KQD5|C9KQD5_9FIRM Vitamin B12-dependent methionine synthase family protein OX=500635 OS=Mitsuokella multacida DSM 20544. GN=MITSMUL_05450 PE=4 SV=1
-KNIRNHVSG-TIHIFDGAMGTMLQAGGLEAGGCPELMNIDHPEVVRHIHEAYIEAGATIIETNTFGASRLKLDHGLRVEELNTAAVRIAKEAAGRK--V
AGSMGPTGRFISPLGDLDFEEAYACFKEQASALAKAGVDFFIIETCIDIQEMRAALLASKEVAAIPVICQLTYSDGRTVTGTDPQSAAIILSHMGADIIG
VNCSLGPEQLVPIVKTLAASCDCPISVQPNAGMPQL-VDGVTHFPMGPEDFGSWGPKLLAAGATYLGGCCGTTPAHIRALRAALEGQAEPVREPL-PKRL
WLASRSRSVCVDKDLPTVLIGERINPTGRKKLAAEIREGSLLSVKKEAVNQVKAGARLLDVNMGVAGIDATKAMKQAVTEIAQLTDAPLAIDTSDAAALE
AGLRAYPGRALINSVTAEDDRIRDFLPLAKKYGAAILCLPITEDGVPKTAEDRLKAIEYIVGKAKENGLNDGDFLLDALVMTVSADKNACREVLKTLQLY
RQRLGYPSTMGLSNISFGLPNRPLINSTFFAMCLAAGLDAPIMNPYDESMQKALKASAALLGDDPCGLAFSQDE----AN-----LAVKAAM--KTPILD
IKQAVIEGEKDVIVGLVVQALQEGKSSNEITEKGLTAAMTEIGEDFGSGRMFLPQVLLSAETMRAAFDKLKELI--PASEADKGTFVIATVKGDVHDLGK
NITGALLANSGFKVIDLGKDVEADTIVETALEQNADVVGLAALMTTTMPQIDKVIDKLRRAGARAKVMIGGAAVTQDYADSCGADAYAADGVKAVKLAKQ
IVG
>tr|D9R4F1|D9R4F1_CLOSW Homocysteine S-methyltransferase OX=610130 OS=/ WM1). GN= PE=4 SV=1
-A-ILEEIKK-RMVFFDGGTGSLLQACGLEPGELPETWNVKHPDIIAKLHRDYLEAGADIIKTNTFGANGLKFHKEFDLEEVVTAAFRNARNAVDT-GYI
ALDLGPTGKLLKPLGDLDFEDAYQMFSKVVKIGEREGADLVLIETMSDSYEAKAAVLAAKEN-SLPVFVTMIFDKGKLLTGGNVESTVALLEGLGVDALG
INCGLGPVQMKSILADIMKVVSIPVIVNPNAGLPRS-EGGKTVYDIDAGEFADAMKEIAEEGACVIGGCCGTTPEHIKKTVALCKDFPVRLPDR--KNRT
VISSYSQAVLIGD--DPVIIGERINPTGKSKFKQALRDHNLEYILREGVTQQDNGAHVLDVNVGLPEIDEPSMMVEVIRELQSIIDLPLQIDTSNTEAME
WAMRVYNGKPLINSVNGKKEVMETIFPLVKRYGGVVVALALDEDGIPETADGRIAVANKIYEKAGEYGIEKKDIIIDALCMTVSSDSKGALTTLETLRRI
RDELGGRTILGVSNISFGLPQREIINSTFFAMALQNGLSAAIINPNSEAMMRSYYSFRTLAGLDPQCSGYISVYSGQVAT------LGETVK--QGTDMP
LSESIAKGLKDRAHAAVTELLKEL-EPLTIINEEMIPALDRVGKGFENGTVFLPQLLMSAEAAKAAFEVIKEKMAEGGMQEKKGKIILATVKGDIHDIGK
NIVKVLLENYSYDVIDLGKDVPPEKIVETAVREGVKLVGLSALMTTTVPSMEETIRQLRETAPAVKVMVGGAVLTEGYAKTIGADQYCRDAMASVNYAEG
IFH
>tr|G6B9E2|G6B9E2_CLODI Putative 5-methyltetrahydrofolate--homocysteine methyltransferase OX=997827 OS=Clostridium difficile 002-P50-2011. GN=HMPREF1122_02468 PE=4 SV=1
-VEIRQYLKN-NILIFDGAMGTMLQQKGLKLGENPEVFGLQNPDKLIEIHTAYLEAGSNVILTNTFGCNELKLDSKYTVEEVIDNAVLVARKAIENKRYV
ALDIGPIGEMLEPMGTLSFDKAYEIFKRQVLQGVKSGVDVIVIETMMDLYEAKVAVLAAKENSDLPIFCTMTFDGGRSFTGCMPECMVATIEGLGVDAIG
VNCSLGPKQLLPIVEKIASRATVPVMVQANAGLPNI-VDGEAIYDVDAKEFFEGVKKFVEVGATIIGGCCGTNPSFIKEISENINSVTKGCIEK--IDEC
VVCSPSKFVEVQ---SPTVVGERLNPTGRKSLQEALKNENVDYAINLGLEQVNAGAQILGVNVGLPEIDEKKLMPKLIREIQAVVDTPLQVDSSNVEALE
QGLRYYNGRTIVNSVNGKEESLESILPIVKKYGSCVVGLTLDEKGIPKKAEERFEIAKRIVNRAVSYGIKPKDIFIDCLSLTVSAQQEEAIETIKAITMV
K-TLGVKTILGVSNISFGLPNRKALNASFLTLALGAGLDLAIINPNEYSMMEAINSFKILNNTDKGCINYINQYSNINNS-----KKSDSSTKID-KDLP
LDILVERGLKDEAKNITLNLLKEK-DENYILDEILIPALDKVGKRYDSGDIFLPQLIQSAETVKVSLNTIKETLLSKSNNVSKGKIIVATVKGDIHDIGK
NIVKIMLENYGYEVIDLGKDVPIEEVVEVAKKRNIKLVGLSALMTTTVQSMKDTIQALRDNEINAKVFVGGAVLTEEYAEEMGADYYSKDAKSAVEIAKL
NF-
>tr|F1T967|F1T967_9CLOT Homocysteine S-methyltransferase OX=588581 OS=Clostridium papyrosolvens DSM 2782. GN=Cpap_3478 PE=4 SV=1
-MQFKKLVSQ-KIQILDGATGTELQKRGMPTGVCPEQWVIENPNAIKEIQKAYIDAGSNIIYTCTFGGNRVKLEEGLRTFEINQRLAQLSKETAAGKCLV
AGDLASTGRFIKPLGDMSFEACVDIYKEQVQGLLAGGVDLFVIETMLDIQEARAALLAVKESCDLPVCVSMSFDSMRTLTGTDPVTALITLQSLGADAVG
CNCSTGPEHMVEIITRMKPYARVPLMAKPNAGLPKL-VNNVTVFDMGPEEFGSFAENFIQAGVNIIGGCCGTSPEYIKELYRNCGDLKPRHFEY--SEYS
AITSSAKTVFFGINKPVAIVGERINPTGKKKLQAELKEGSTNEIRRFALEQMEKGADILDVNVGMPGIDEKEVMLNTVRLLGSVCDAPLCLDSSSPEVLE
AALRIYPGRALINSISQEKVKLDKLLPVAAKYGAMFILLPLNDEGVPEKAIQRQVIVQEVFNQASDYGYKKSDIVVDGLVMTVSSNQEAALETLKLIQWC
REEFGCGTIVGLSNVSFGLPERGWVNAAFLSMAIAKGLTMAIANPSSDLLMCIKMACDVIMTNDVNSRNYISYFDK-GNE-----KKEAEKT--C----D
IFDAVLNGDNEGIDKLIEKAIAEKTPPQDIVDIYLIPAINQVGKLFDEKKYFLPQLIQSAETMKSGFTFLEPLLKQKGEKEEDIVVVIATVKGDIHDIGK
NIVGLMLRNYGFKVHDLGKDVSAERIIDEAKKLKAHIVGLSALMTTTMVEMEEVIKLAKEKNVGCKFMIGGAVVDDDYAKTIGADGYSKDAYEAVKLAKK
LSI
>tr|D6KPH1|D6KPH1_9FIRM Vitamin B12-dependent methionine synthase family protein OX=450749 OS=Veillonella sp. 6_1_27. GN=HMPREF0874_00855 PE=4 SV=1
------------MYIFDGAMGTMLQAAGLEEGYCPELFNIERPEVVKDIHAQYLLHGSDVITTNTFGACGLKLEDDLRVREINIAAVKVAKEAIATR--V
AGSMGPTGRFLQPLGNMSFDSIYDTYREQAEALIEGGVDFIIIETIIDVQEMRAALLASKTKDDVQIICQFSFSDGRTITGTPPAVATTIVEAMGADIIG
INCSLGPEQITPLIEEIASVTNLPISCQPNAGMPQL-INKQTVFPLTAEEMGPLMLAIVDAGASYVGGCCGTTPAHIQSISNAVKAHTPKERAHI-APKT
IITSRTKLLELGHHTKPLIIGERINPTGRKVLAQELRDGSFIRVKRDALDQVEAGADILDVNMGVAGMDQSPLMERAIFELSMLVETPLSIDTLDPAAME
IALKNYPGRALINSVNGEEESITHVMPLAKRYGAALLCLPICSGDLPEKAEDRVALAESIVNRAYGYGLHPHDLLLDPLVLTLASGEDSARQTLRTLQLY
KEKFGFPTVMGLSNISFGMPQRPYLNGQFLTMALACGLTTPIMNPLNYPAKKAFVSSTTLLGWDPGSAEFIKEYDETTPG-----NTAKPDK--SFDPLA
IRACVEQGEKEAIIDLVKKALADGIDPLDLTKKGLSEAMNVVGDKFGSGKLFLPQVMLAAETMQAAFNTIKEII--PASSLDKGTVVVATVKGDIHDLGK
NIVAALLENNGYKIVDLGKDVDPEVIVQAIKDNKAALVGICSLMTTTMPQIDNTIAAIRAAGLKTKVMVGGAVVSQDYADQAGADIYAKDGIAAVNHAND
FFE
>tr|B7AQQ5|B7AQQ5_9FIRM Putative uncharacterized protein OX=483218 OS=[Bacteroides] pectinophilus ATCC 43243. GN=BACPEC_01012 PE=4 SV=1
-MNFRDLLN--EYVILDGAMGTMLQAAGMKMGETPEVLSITQPELLENIHSQYIKAGSQIVYANTFGANPYKLEGGYSLEEIVKAAIANARRASDADALV
ALDIGPIGQLMEPTGTMSFEEAYDMYAQLIKAG--SDADLIVFETMTDLLEVKAGVLAAKENSDLPVMVTMTFENHRTFTGVSVQSMALTLEGLGVDAIG
VNCSLGPKELEPVVKELADWTNLPIVLKPNAGLPDP-KTN--KYNLSAADFAESMKILLPYGIKVFGGCCGTTPDFIRELKNMLEGNPATHSK---KTGA
AVCSPTQAVAIS---QPRIIGERINPTGKKLFKEALLNNDIDYILNQALEQVKGGADILDVNVGLPGIDEKEMMVKVVKALQGIVDVPLQIDSTIPEVLE
AALRVYNGKPIVNSVNGEEKSLATVLPLVKKYGAAVVGLTLDEGGIPKKAEDRFRIAQKILDRAQAIGIPKEDVFIDCLTLTASAEQENVMETINALHRV
KTELGLKTVLGVSNISFGLPNRELVNHIFLAMALNNGLDLPIINPNNEAMTGTVRAYKLLANYDVNSVEYIKAYANDDNA-----SGAAAKA--D-GNA-
LMHAVLNGLKTEGAQCTEELLKTM-DSMEIVNDILIPALDRIGADFEKGKIFLPQLIQSAGVAQAAFEVIKKQMAGKDKPVSKGKIVIATVKGDIHDIGK
NIVKVLLENYGYDVIDLGKDVEYQAVVDAVRESGAKLVGLSALMTTTLVSMEETIKLIHENNLDCKIMVGGAVLTPEYAEQIHADFYAKDAKESVDIAKR
VIG
>tr|C7H8B4|C7H8B4_9FIRM Putative 5-methyltetrahydrofolate--homocysteine methyltransferase OX=411483 OS=Faecalibacterium prausnitzii A2-165. GN= PE=4 SV=1
---ANELFRP-NTILLDGGMGTMLQAAGLKLGARPEELNITDPALIESIHARYAAAGSRIINANTFGASAHKLAGEYTLEEIIAAGIANCKRACAP-ALA
ALDVGPLGELLEPNGTLAFEDAVAEYGRIVRAGVAAGADLVFLETFTDLYELKAALLAVKENSSLPVLASMSFEGGRTFTGCTVESFAATARGLGADAVG
INCSLGPKEIFPMAKRLTEALSFPVFVKPNAGLPRA-DGS--GYDITPQLYAMQMKPYRELGLFAAGGCCGTTPEFIQLLNGVFADCRPGRPDH--PMKS
VVCSPMDCVDVD---GITVVGERINPTGKKRFQQALREGDMNYVLEQAVSQTEAGAQILDVNVGAPGVDEPALMEQVVKALQSVVSLPLQLDSSHAEALE
RGLRVYNGKPIVNSVNGEEEKLNTILPLCKKYGAAVVGLAIDERGILPKAEDRVAIARRIRDAALAAGIPQEDIYIDCLTLTASAQQEDVLATVQALHAC
KEELGVRTILGVSNISFGLPCRSYLNTTFLTMAMYAGLDLAIMNPSSEEMMAAVYAYNVLTNRDKQSTKYIERYANALVQ-----AVQNAQT--A-PAAT
LMKAVEKGLKGEAAARTRALLEEK-EPLELVDEALIPALDIVGAKYEKGTLFLPQLLQAATAAQGAFEEIKTAIAQKGGSASKGRIVIATVKGDVHDIGK
NIVRVILENYGFEVIDLGRDVPVETVVNTVREKDVHLVGLSALMTTTLKSMEETIRALHDAKLDCKIMVGGAVLTPEYAKKIGADWYAKDAKQSADIAKE
FFG
>tr|A0Q0N0|A0Q0N0_CLONN 5-methyltetrahydrofolate--homocysteine methyltransferase, putative OX=386415 OS=Clostridium novyi (strain NT). GN= PE=4 SV=1
-MNVLQYIKD-NILIFDGAMGTMLQKSGLNLGESPEKLNFSHENLIIDIHKKYIEAGANVITTNTFGANELKLKNSFSVEDVIYKAVSLAIKAKED-CFI
ALDIGPIGQLLEPMGTLKFEDAINIFKRQIKAGVKAGVDLILIETMTDLYEMKAAILAAKETCDLPIFATMSFEDGRTFTGCLPESMAVTLEALGVTAVG
VNCSLGPKELKPIVKKTLEHTNLPVIVQPNAGLPTI-VNGQSLYTITPEEFCNYVESLIDMGVSIIGGCCGTTPDFIKCLKSMSHHKKVLKRDP--IKKS
FLTTPSKILELN---EVRIIGEKINPSGKKNLKEAIINDDMDYILKQAITQLNGGADILDINVGLPEINEANILENTIKEIQSRIDIPLSIDSSNLEAIE
RALRIYNGKPIVNSVNGENSSLETILPLVKKYGASVIGLTLDNKGIPKTAGERFEIGKKILNTALEYGIKKEDVYIDCLTLTVSAQQKEVMETLKALKMV
KENLGVKTLLGISNISFGLPNRDIINETFLSLALGAGLDLPIMNPNNENMINIINAFKVLNNNDKNAKHYIETYKDNSSN-----ESLNPAF--K-NEAS
LENSILQGLKSNTKDLVKELLKTN-NELNIINDYLIPALDRVGDRYESGEIFLPQLIQAAETVKIAFDLIKENLNRNNKEITKGTIMLATVKGDVHDIGK
NIVKVILENYGYEILDLGKDVPIERIVKEAIENDIKLVGLSALMTTTVKSMEDTITALKKANFKGKIMASGAVITKDYSIKMGADFCAKDAKDSVEIAKL
VFG
>tr|K9DIF9|K9DIF9_9FIRM Methionine synthase OX=883156 OS=Veillonella ratti ACS-216-V-Col6b. GN=HMPREF9282_00364 PE=4 SV=1
------------MYIFDGAMGTMLQQSGLVEGECPELFNVEHPEVVTGIHAAYLKNGSDIVTTNTFGACSLKLADGLRVAEINSAAVKAAKKAIASK--V
AGSMGPTGQFIEPLGQIFFDEVYATYYEQASALIEAGVDFIIIETIIDIQEMRAALLAAKTETDVKIICQFSFSDGRTITGTPPEAAAILMEAMGADVVG
INCSLGPEQLIPLVERLASVTNLPISAQPNAGMPML-VGRETVFPLSPEEMGSFVPALIDVGATYVGACCGSTPQHIAEIAKAAKAHTPKERKEV-VPFT
AFTSRTGFVKVGHTEKPIIIGERINPTGRKVLAKEIKEGSFAMVKRDALAQVAAGADVLDVNMGVPDVDVAAVMKRAIMELTMLVDVPLSIDTLDPAAME
AGLKAYPGRPLINSVNAEPEQLAQVLPLAKRYGATVLCLPLGRGDLPATAEQRIELAKEIVLAAYEKGLRSEDLLLDPLVLTLASGQDSAVQTLRTLAMY
KETFGFPTVMGLSNVSFGLPQRPYLNSQFLTMALSHGLTAPILNPLNATVKKAFIAGRTLLGFDPAATEFIADYEENTTS-----SAAKVTV--SFDPLE
IQHAVEQGEKELVIELVEKALADGLDPLKITKHALSEAMNVVGEKFGAGKVFLPQVMLAAEAMQGAFQTIKRVL--PDAGITRDTVIVATVKGDIHDLGK
NIVAALLENNGYRVIDLGKDVEPEEIVAVVKRENATVVGICSLMTTTMPMIDVTIDAIREAGLPAKVLVGGAVLTQEYADKAGADSYAKDGISAVNIVKH
LLG
>tr|F9N5I0|F9N5I0_9FIRM Homocysteine S-methyltransferase OX=944564 OS=Veillonella sp. oral taxon 780 str. F0422. GN=HMPREF9200_1208 PE=4 SV=1
------------VYIIDGGMGTMLQAAGLGDGACPELFNVEHPDVVEHIHAEYLRHGSDIITTNTFGGTALKLDEQLRMDEINRAAVKVAQAARDNK--I
AGDMGPSGRFMAPLGVAQFDEIYETFRDQARALIDAGVDYLIIETIIDIQEMRAALLGAKTKEDVKIICQFSFSDGRTITGTPPEAAAILMDAMEADIVG
INCSLGPEQLLPLVERMAAVTNLPISIQPNAGMPQL-VGKETIFPLGPEEMGKYAPRFLDAGATYLGACCGSTPKHIESIAKAARAHTPAERPHV-EPFT
AFTSRTSVVKVGLQEKPIIIGERINPTGRKVLAEEIRKGSFLMVKKDALAQVEAGADVLDVNMGVTGVDPGETMKRAIEELTMLVEVPLSIDTLDPVAME
AGLKAYPGRPLLNSVNAEPEQLEAVLPLAKRYGAALLCLPLGKKELPETAEERVSLAKEIVLEAYNYGLRPNDLLLDPLVLTLASSQHAARETLKTLKLY
AETFGFPTVMGLSNISFGLPQRAYLNAQFLTMALSSGLTCPIMNPMNEIVRKAFITGRTFMGFDPAAADFIAEYDENAVT-----KKVKATE--AFDPIE
IKHAVEQGEKEAVVPLVKEALAQGLDPLEVTRRGLSDAMAVVGEKFGSGKAFLPQVMLAAETMQAAFTTIKEVL--PEGAEKKATIILATVKGDIHDLGK
NIVSALLENNGYQIVDLGKDVSPEEIVAAAKEHNAPIIGIASLMTTTMPMINETIAAIRESGVDAKVLVGGAVLSQAYADEAGADSYAKDGISAVNIVKG
LLG
>tr|E0P2T0|E0P2T0_9FIRM Vitamin B12-dependent methionine synthase OX=864563 OS=Selenomonas sp. oral taxon 149 str. 67H29BP. GN=HMPREF9166_2397 PE=4 SV=1
------MGMN-DIIILDGGMGTELQARGLAPGERPELFGMEHPDVVEEVHCNYIAAGSRVIYSNTFGANGHKLIGGKSVAEVIAANVATARRAAEHEVRV
ALDVGPIGELVEPLGTLSFEEAYELFREMVTAGAAAGADLVVFETLTDLYEVKAAVLAAKEHTKLPIWVTMTFENGRTFLGAAVSSVAVTLDALGIAALG
VNCSLGPAELRPIVAEMMEWTDLPIIVKPNAGLPDP-RTG--AYEMTAEMFGAEMLHFAQSGALILGGCCGTNPDFIRCLAETVAGGAADRPAR--KKRK
GLASPGRVAEYG---KVNVIGERINPTGKKRLQQALLEEDMGYIKKLAIAQQEAGAQVLDINVGAQGVDEAAIIPQVVKAVQSVVDLPLQIDSANPTVIE
AALRVTNGRAIINSVSGERARMDAIFPLAKHYGAAVLGLAMDESGLPETAAQRVAIAERIVAEAETYGLDREDIVIDCLTLTISAQQEQAMETLRAVREV
HERLGLHCALGVSNISFGLPARVHMTVNFLIQAMHVGLDFPIINPNTKEVMDAVVSFRAVSGEDADCAAYIERFAARKEL-----GITDAAA--D-VKSD
LMDAIMRGLSDDAEQIARRLLANT-APMDIIQNKVIPALDIVGDRYEKEIIFLPQLINAANAATSALELIKAKLAENGQGISKGKVILATVEGDIHDIGK
NIVKVVLENYGYQIIDLGRDVPVQRVVEVAIEKKVGLIGLSALMTTTVTAMKRTIDALHEAGHECQTVVGGAVLTEDYAREIGADYYAADARSAVEIARS
VLG
>tr|D5HGD3|D5HGD3_9FIRM Methionine synthase (B12-dependent) OX=751585 OS=Coprococcus sp. ART55/1. GN=CCU_26970 PE=4 SV=1
-MDFRKLFDD-KILILDGATGTNLMNAGMPLGVCPEKWILEHPQIMFDLQVAYLNAGTDILYAPTFTCNRIKLNEGLDLEDMNRRLVKLSKEAVKAHGLV
AGDITMTGEMLYPMGKLKFEELVDVYKEQIKVIDESGCDLLVVETMMSLAETRAAVIAANEVSDLPIIASLTFNDGRTLYGTDPVTAVNVLQNLGVAAIG
VNCSTGPDKMVELVRQMKSIAFIPVFAKPNAGMPEL-VNDKSVYRMTPEEFAEDMKMIIEAGAGMVGGCCGTRPEHIKALADMASKMPVPEISS--EHVR
CISSERSSLIIDLDAPFKVVGERINPTGKKKLQAELREGSLELVMNMAEEQVDKGASILDINVGMNGIDERDMMLKVVYQVSQAVNLPLCLDSSSPEVLE
AALRIYPGRALVNSVSLEKVKMEEILPLVKKYGAMFILLPLSDKGLPESPQEKEDIINTVLGTAYEMGFTKNDVVVDGLVATVGAQKDAAINCLKTINYC
YNN-GLATICGLSNISFGLPERMFVNTAFLTMAISRGLTMAIANPSQTMLMNAAFASDMLLFKEESDVRYIENV---PLE-----LASPGAG--ASGKAS
IYIDVLKGNKRSILDDVHAVLDSGADPQSIIDNDLIGAINEVGRLFEKKKYFLPQLISSAETMEMAIGVISPLVLKDKDSSDMPTIVVATVEGDIHDIGK
NLVVLMLRNYGFNVIDLGKDVPCDVIIQAAKDNNASIIGLSALMTTTMVKMKDVVEAVKENGLDSKVVIGGAVITESYAEEIGADGYSEDAANCVVVVKN
LLG
>tr|C0B742|C0B742_9FIRM Putative 5-methyltetrahydrofolate--homocysteine methyltransferase OX=470146 OS=Coprococcus comes ATCC 27758. GN= PE=4 SV=1
-M-IRERLGK-ELLFLDGGMGTLLQAEGLAPGELPETWNIEHPEKVEAIHRRYYEAGSDVVLANTFGANICKFHDRYTVEEVIRAGIANAK---RAETYV
ALDMGPTGKLLKPMGDLDFDDAYEAFAEAVRYGEKYGADLIHIETMSDTYEVKAAILAAKENSSLPVFVTMIFDRGKLLTGGDVPSVVAMLEGLRVDALG
LNCGLGPKQMLPILNDLRRYTSLPIIVKPNAGLPKQ-KNGETYYDVEPDEFARIMQEVVKGGACVIGGCCGTTPEHIKKLVEECKDLPLREIEK--KHDT
IVSSYGQAVILDD--MPRIIGERINPTGKKKFKEALKNEDMDYILKEAITQQDKGAHILDVNVGLPDIDEVAMMEKVVKELQSVTSLPLQIDTVDGKAME
RAMRIYNGKPMINSVNGKQVSMDEVFPLVRKYGGVVVGLTIDEEGIPKDAEGRVRVAGKIINEAAKYGIDKKDIVIDVLTMTISSEKDGAKVTLEALKRV
REEFGVRTVLGVSNISFGLPRRPIVNSYFYAMAMQNGLTAGIINPSSEDMMKAYRSYNALMGFDENCTNYISTYAGTTET------VTVQAS--Q-AEMT
LKYAIERGLKEEAHHITRDLIGTR-EPLDIIQEELIPALNVVGEGFEKGTVFLPQLLMSADAAKIAFAVIKDVLASSGQEEKKEKIILATVKGDIHDIGK
NIVKVLLENYGFDVIDLGKDVPPEAIVEKAVEENVTLVGLSALMTTTVVSMEETIKLLREKKPDCKVMVGGAVLNQDYADMIGADFYGKDAMQSVHYAQK
FFG
>tr|B0TAJ7|B0TAJ7_HELMI Methionine synthase, putative OX=498761 OS=Heliobacterium modesticaldum (strain ATCC 51547 / Ice1). GN= PE=4 SV=1
------------IKLFDGAMGTMLQAAGLLPGACPERFNLEHPERVTAIHRRYVEMGAEIIETNTFGATRLKLAHRMQVEAVCHAAVRAARAACGAK--I
AGSVGPTGKLIAPLGELSFEEAVDVYSEQISALAAVGVDYILIETIIDIQEMRAALLAAKAVAKVPVICQLSFGDGRTVTGTDPATAAYLLEAMGADVIG
VNCSLGPAQLLPVIEAIAGATNLPISAQPNAGMPEL-IDGRTVFPMSPEEFASWAPKLAAAGATYLGGCCGTTPEHIAAAKAALEAAAAPARLIK-DPVT
ALTSRSRTVFLGPAFSPVIIGERINPTGRKALAAEIKGGSWLTVKRDAIEQVRAGAQILDVNMGVPGINQAKAMETAITELSLLVDVPLAIDTTDAAALE
AGLRVYPGRALINSVSAEPDRLREFLPLAKKYGAAVLCLPIAPGGVPQTAQERVAIAQQIVDAALAAGLRRQDLLLDPLVMTVATDANAARETLETLRSY
RKTFGFPTVMGLSNVSFGLPRRNLVNAAFCALALDAGLDAPIMNPFDETLSDCWNAAQVLLGHDKQGQRFCIRY----AQ-----SAGPSAN--AADVLT
IRKAVIAGEKESVIPLVRKALAEGLTAIAITEGGLTTAMTEIGEAYGSGRCFLPQVMLAAETMRVAFQTLKAEL--PSQMASKGRVLLATVRGDIHDLGK
NIVAALLENNGFTVIDLGKDVPAERIVAEARAQRADVVGLCALMTTTLPEIDHTIAALKAAGVECLTMAGGAVVTAEYAAAAGVDGYAPDAVSAVKLTEE
LLK
>tr|K8EDR4|K8EDR4_9FIRM Homocysteine S-methyltransferase OX=1121428 OS=Desulfotomaculum hydrothermale Lam5 = DSM 18033. GN=DESHY_10106 PE=4 SV=1
-LSFRERIKR-EILVVDGAMGTLLQQLGLPAGWCPEEWNLSRPASVQEVHKLYLAAGADIITTNTFGAIRLKLADGLLVREINLAAVSLAKEAARGM--V
AGSVGPLGKFLQPLGTMTFDEAYEQFYEQCRALVEAGVDLILFETFGDIGEMRAALIAAADAGPVPVVASFTFDTGRTFTGTDPETAAVVVERLGVAAIG
VNCSVGPRELVPVVQQLTQSTNLPVLVSPNAGMPEM-VEGRTVFRETPATMAEFAARFVAFGASLLGGCCGTTPEHIKAIQQSVKGLPLKERNRD-FG-L
RVASRVKTVTVHPQAMPVAVGERLNPTGKKALQAEIREGKTEITRRDALAQVAAGAAILDVNVGVGGVDQVAAMERAVQAVQVLVDAPLCIDSTDPAVIE
KALKIYHGKAIINSINGEEKSLQTILPLAKRYGAALIGLTLDEGGIPATAEERLAVARRLVERVEAMGIPRSDLMIDCLVLTVSAQPAGVPETLKAISLV
KKELGLTTSLGVSNVSFGLPNRGLINAAFFAMALAAGLDAAILNPQEQRMMETLRAAAVLTGRDPQAAGYI---HAQEAG-----IQVPPAQ--AA-PLE
LYQAVLSGDKDNIVAYIENALAEGLSPMEMLDKALIPGIEEVGRRYGAGQYFLPQLMMAGETMTKSFARLRPEL--AKGSKRVGTVILATVKGDIHDIGK
NIVSVMLANHGFEVIDLGKNVDNEDIIAAAKQHQAQIIGLSALMTTTMVHMADLIKRVKEQGLNFKVMVGGAAVTAQYAREIGADGYAVDAVEAVSVAKG
LVG
>tr|F1ZYL4|F1ZYL4_THEET Homocysteine S-methyltransferase OX=509192 OS=Thermoanaerobacter ethanolicus JW 200. GN=TheetDRAFT_2404 PE=4 SV=1
-LDIFKELSN-RVIVFDGAMGTQLQERGLKSGECPEYMNITHPEVVFDIHRSYIEAGADVIETNTFGANRIKLAKGLENENIVTQAVKIAKEASKD---V
ALSIGPIGELLTPYGDMTFDEAYDVFKEVVIAAERAGADIVLIETMSDMLEAKAAILAAKENSNMKVICTMTFQDGRTLMGSDPITVVVSLQGLGLDAIG
VNCSTGPDKMVSVVEKMSQVSRIPIIAQPNAGMPVI-RDGKTVYDLKPEEFASFFPLLVEKGASIVGGCCGTTPHYIKLVKKAVKDLKPKVKVN---KFT
AVASNTKTVFIGENYLLRVIGERINPTGKKKLSEAFLAGDVSLAVEEAIKQQKCGAEILDVNVGVPGVNEEELLPKVVSEIQNVVDIPLQIDSTNIKAVE
KAIRILRGRPIINSVSAKEESLKEVLPIVKKYGACVVGLTVGDKGLPKDRHERIENAKKIIKKAEEYGIPKEDILIDCIVLTVSSEQEAAIETLEAIKLA
KEELGVNTVVGLSNVSFGLPERRLINSTFLAMAASYGLTTAIINPCDEAMMDTLRASMVLLNKDKGSVNYLNIYGKKQKE-----EKEEQQK--I-QEED
LKSKILEGKKSGVEDIVKNILEEEVQPLSIVDNIIIPALKEVGDRYEKGIYFLPQLLSSAEVVQSAFKIIKEKL----KSVSKGKIILATVEGDVHDIGK
NIVKVLLENYGYDVIDLGKDVKGEVILEEVKRTGAPLVGLSALMTTTLFNMEKIIKLLKANT-DVKIMVGGAVLTEEYAYKIGADYYGKTAQDAVKIADK
FF-
>tr|A7VBG6|A7VBG6_9CLOT Putative 5-methyltetrahydrofolate--homocysteine methyltransferase OX=411489 OS=Clostridium sp. L2-50. GN= PE=4 SV=1
-MEFRQLFDE-KILILDGATGTNLMNAGMPLGVCPEKYILEHKEVMLELQTSYLNAGTDILYAPTFTCNRLKLREGLNLYQMNMDLVALSKQAVAEHGYV
AGDLTMTGEMLYPMGKLQFEELVDIYKEQIKVLVEAGCDLLVVETMMSLAETRAAVIAANEICDLPVMASLTFNDGRTLYGTDPVTAVNVLQNLGVDAIG
VNCSTGPDKMTELVAAMKEVAFVPVFAKPNAGMPEL-VDGKSVYAMTPETFAEDMKMIIEAGAGMVGGCCGTTPAHIKALSDMAKTMDIPEISD--KKER
LLSSERMTRQISLDGPFMVVGERINPTGKKKLQAELREGVLDTVMTMAEEQMEKGASILDINVGMNGIDEKEMMVRVVYEVSQAVNLPLCIDSSNPAVIE
AALRIYPGRALVNSVSLEKVKMQEILPLVSKYGAMFILLPLSDEGLPKDSDEKENIIHTVLDAAYKMGFQKEDVVVDGLVATVGAEKAAAVNCLKTIRYC
HDM-GLATICGLSNISFGLPERMFVNAAFLTMAIQNGLTMAIANPSQTMLMNMAYASDMLLNKDEGDIRYIQNV---PLG-----ITTAAPV--QNGSQS
IYTDVVKGNKRNISEDVKKELEQGIDPQKIIDDELIPAINRVGKLFEQKKYFLPQLIASAETMELAINQITPLIVREDDGKAMPAIVVATVEGDIHDIGK
NLVVLMLRNYGFPVIDLGKDVPADVIVDAAIENDAKVIGLSALMTTTMMKMVDVVELVKEKNLDIKVVIGGAVITESFAEEIHADGYSEDAAECVQVVKR
LLD
>tr|K9CIY6|K9CIY6_9FIRM Methylmalonyl-CoA mutase domain-containing protein OX=999423 OS=Selenomonas sp. F0473. GN=HMPREF9161_00453 PE=4 SV=1
--------MQ-DIIILDGGMGTELQARGLAPGERPELFGMEHPEVIEEVHRSYIAAGSRVVYSNTFGANRHKLVGGKTVAEVIGANVAIARRAAENSVRV
ALDIGPIGELIEPLGTLSFEEAYELFREMVTAGEAAGADLVVFETLTDLYEAKAAVLAAKEHTKLPIWVTMTFENGRTFLGAAVPSVAVTLDALGVAALG
VNCSLGPVELLPIVHEMMEWTDLPIIVKPNAGLPDP-RTG--AYEMTAKEFGTEMAEFARRGAVIMGGCCGTNPDFIRALTRATAAGAAERLAR--KKRK
GVASPGCVAEYG---KLNVIGERINPTGKKRLQQALLEEDMGYIQKLAISQQEAGANVLDINVGAQGVDEESIIPRVVKAVQSVVDLPLQIDSANPKVIE
AALRVTNGRVIINSVSGERARMDDIFPLAKHYGAAVLGLALDESGLPESAAARIAIAERIIEEAERYGLDREDVIVDCLTLTVSAQQEQAMETLRAVREV
HDRLGLHCALGVSNISFGLPARVHMTENFLVQAMHVGLDFPIVNPNTKEIMDAVVSYRAVSGEDVDCAAYIARFAPRKEL-----GLTGDAG--A-DAAT
LMDAIIRGLSDDAERITRRLLTEM-APMDIIQEKVIPALDIVGDRYEKEIIFLPQLINAANAATAGLELIKVKLAEAGQGVSKGKIILATVEGDIHDIGK
NIVKVVLENYGYQIIDLGRDVPVTRVVEVAIEKKVGLIGLSALMTTTVTAMKRTIEALREAGHDCQTVVGGAVLTEDYAREIGADYYAGDARSIVEIARR
VLD
>tr|J1GZE8|J1GZE8_9CLOT Homocysteine S-methyltransferase OX=1105031 OS=Clostridium sp. MSTE9. GN= PE=4 SV=1
-M-IMECINQ-GIFYLDGGTGTYLQEQGLAPGELPETWNLLHPEKIKDLHRQYYEAGSHLVCTNTFGANGLKYDQRFSVKEVVSAAVNCAKTAREEDRFV
ALDIGPLGKLLAPLGDLDFEDAVSLFAEIVQAGAEAGADCVLIETMNDCYETKAAVLAAKENCSLPVFVSNVYDTGKLMSGTTPEAMVAMLEGLGADVIG
INCSLGPDKMLELLPRFISCASVPVLVKPNAGLPRS-EGGKTVFDVSAEEFAQTMLRIAAGGARVIGGCCGTTPAYIRLMTDQTKGLPVTPILS--KHRA
VISSYTHAVVFGG--KPVMIGERINPTGKKRFKEALRQKDIGYILKEGILQQEQGAQVLDVNVGLPEIDEPEMLVTCVKELQSVCDLPLQLDTSNQTAME
RAMRVYNGKPMINSVNGSDESMSAIFPLVKKYGGFVVCLTLDGSGIPETAEGRFAIAERIVRRAAEYGIAACDLIFDPLAMTISSDQQAAQVTLDTIPMI
QGRLGVCCSLGISNISFGLPNRDFITGTFFIMALVKGLSAAIMNPFSFEMQKAYHSYLALAGLDDNCQEYIRFSQNVPS-------DTVTVS--K-APAG
LQGAILRGFSAEAAELAKEKLEST-EPLALIQEQIVPALDIVGKGFEAKTVFLPQLLMSAEAAKAAFEEVRKKLPASDEIG--PAVILATVKGDIHDIGK
NIVKAIMENYGYHVIDLGRDVPPETIVESAIENQVKLVGLSALMTTTVPAMAETIRQLKEKKPDTLVMVGGAVMTQEYADQIGADFYGKNAMESVRYAER
VLK
>tr|E9RU86|E9RU86_9FIRM Putative uncharacterized protein OX=552395 OS=Lachnospiraceae bacterium 4_1_37FAA. GN=HMPREF0490_01017 PE=4 SV=1
-M-LLERLGK-ELLFLDGGMGTLLQEKGLQPGELPESWNLKRPEEVIAIHQNYFEAGSDIVLTNTFGANALKFHSDCPLQEVVARAVENVREAARREIYV
GLDIGPTGKLLKPMGDLAFEDAYEAFAEVMEYGEKAGADLIHIETMSDTYEVKAAVLAAKERTSLPVFATMIFDRGKLLTGGDVPSVVAMLEGLRVDALG
INCGMGPEQMLSILEELLTYTSLPVIVKPNAGLPKQ-RNGQTYYDVVPEEFASTMKLIVEKGACIIGGCCGTTPAHIRQMTTLCQGMKAVPPVK--KHHT
LVSSYGTCISFGR--KPVIIGERINPTGKKKLKQALKDGDFDYILKEGIMQQEKGAHILDVNVGLPDIDEVAVMEKVVTELQSVTSLPLQIDTVLPEAME
RAMRIYNGKPMINSVNGKQESMDQVFPLVQKYGGVVVALTIDEDGIPDTAEGRLAIAEKIICEAEKYGIDRKDIVVDVLAMTISSEPEGALVTLKALKLV
REVCKVNTVLGVSNISFGLPKRPVINAHFYTMAMQQGLTSAILNPFSEEMMNSYYAFCALMNYDENCASYIERYSKTVEE------EQQSIA--G-SEMS
LQTAIERGLKEEAGHLTRELVREK-EPLAIIQEQLIPALDVVGKGFEKGTVFLPQLLMSAEAAKEAFAVLKEVLERSGQEQKKGKVILATVKGDIHDIGK
NIVKVLLENYSFDVIDLGKDVDPEVIVHTAKQEGIRLVGLSALMTTTVVSMEETIRLLREHCPDCKVMVGGAVLNPEYAEMIGADFYGKDAMQSVYYAQR
VFA
>tr|D2RMA2|D2RMA2_ACIFV Homocysteine S-methyltransferase OX=591001 OS=Acidaminococcus fermentans (strain ATCC 25085 / DSM 20731 / VR4). GN= PE=4 SV=1
-M-FTEALHT-RRLFFDGAMGTMLQEAGLQPGELPETWNLLHPEKVRAIHQAYVRAGVDILKTNTFGANGLKFGAQPEVEELVRAGVENARAAFAADGFV
ALDLGPTGKLLQPFGDLPFAEAVALYAAQVKAGAAAGADLILIETMSDSYEAKAAILAAKENADLPIVCTFTFDDGKLLNGADVTTALVMAESLGVSAVG
FNCGQGPDTLVKLVPQALQAVDIPLVANPNAGLPVQ-KDGKTVFHIDGEGYAPLMVPFAEAGVSVLGGCCGTTPDHIARLIEACRDIPLPAPRS--GAPC
AIAGYGRAVDFEG--MPVIIGERINPTGKPRLKEALKSQNMDYVCQLALEQLDKGAQVLDVNVGVPGVDEPALIEKVILTLQSITSVPLQIDTSNIEAME
RALRIYNGRPLLNSVNGKAENMADVLPLAKKYGAALVGLCLDEGGIADTAKGRLEVADKVIAEAGKYGIPARDMVMDPLAMTISTGGQNARIDLEVIRQL
KAR-NIKTVMGVSNISFGLPSRDAVNSAFFALAMEAGLSAGIINPNSGAMMGAYIAYGALSGKDEGCKKYVEYFADAPAKS-----QGGAKP--AAGEYP
LEEAIVKGLTSQVENGVRKQLAEG-KPLDIINESMIPGLNIVGDLFEKKKLFLPQLLVSADAAKAGFEILKQSI-AKGATEKGDPIVICTVKGDIHDIGK
NIVKVLLENYGYQVIDLGKDVPPEEVVKAAREHDARLVGLSALMTTTVGSMEETIRQLRQALPDCRVMVGGAVMTEEYARTIGADFYGANAVASVHYANQ
LFH
>tr|E6ME32|E6ME32_9FIRM Vitamin B12-dependent methionine synthase OX=887929 OS=Pseudoramibacter alactolyticus ATCC 23263. GN= PE=4 SV=1
-MDIKTILGN-ERLYLDGGMGSMIQKRIENPGPIPEELNLTHPEVIGEIQAAYVAAGADILVANTFGANGHKMAGPYSVDEVVRAAVHIAKARH---RFV
AMDIGPTGALIGDLGDLSFDAAKACFAEAVRAGAAAGADLIFIETMTDIYEARAAVLAAKEHCDLPIICSMTYENSRTLTGSDPETVVTILEGLGVDAIG
INCSTGPDKMMPVIDRLLKAASVPIVVEPNAGLPRV-VDGETVYDIDAAAFAGSMCEIAVKGAAVLGGCCGTTPDYIAATIARTRSVALPARGA--RRPM
RIASSTRTVTLGT--DIRVIGEAINPTTNPELKADLRQGRMAVVKRLALEQKQQGADILDVNVGLPEVDEAALMVQAVHAISQVVELPLQIDSTKPEVIE
AVLKNYNGKPLVNSVNGEAASMAGILPIVAHYGAAVLGLTLDDDGIPATAAGRVAVADKLIAEAAKQGIGVEHIAIDCLVLTASAQQAGVRETLDAVRAV
KAKYGVPTVLGVSNISFGLPNRRLINKTFLTMALSAGLDTPIMKAADAEMMNAVSAYRALAGLDDGCMAYVAAYKDQTTD-----AQN-EEN--G-EAVS
VIGMVVDGLKDEIVPVVQEMLTRM-PPMDIVNNYLIPGLDKIGDLFETGEVFLPNLIFAAETVQNAFAEIKKAI--KSEQTVKGTVVLATVKGDVHDIGK
NILRVIMENYGYRVVDLGKDVDPEVIVDAARREGAGLVGLSALMTTTVKNMEITIARLKAELPEVPVMVGGAVMNETYAQSIHADFYGKDARAGVAIADK
VFG
>tr|C5EJL8|C5EJL8_9FIRM Putative uncharacterized protein OX=457421 OS=Clostridiales bacterium 1_7_47FAA. GN=CBFG_00503 PE=4 SV=1
-M-ILEEMKV-RRLFCDGGMGSLLQAQGLKAGELPELWNLTHPEVLRDIHRQYLAAGADIMTTNTFGANGLKYRD--NLEEIVAAAVGHARAAVEE-GYV
ALDLGPTGKLLKPLGDLEFEAAVSLYKEVVTAGAKAGADLILIETMSDSYELKAAVLAAKEAEPLPVFATVIYDKGKLLTGGNVESTVALLEGLRVDALG
INCGLGPVQMKEILRDIMKVTSLPVLVNPNAGLPRS-EEGRTVYDIDEKQFALAMEEIAQLGAAVVGGCCGTTPAHIRETVKRCRDIPVRLPKP--KKRT
VISSYAQAVVIDG--KTVIIGERINPTGKSKFKQALRDHDLEYILREGVSQQDNGADVLDVNVGLPGIDEPSMMEEVVKELQSIIDLPLQIDTSDMEAME
RAMRAYNGKPLINSVNGKEEVMHQVFPLVAKYGGVVVGLCLDEGGIPETAGGRIEVGRKIIDTAASYGIGAEDIILDGLCMTVSSDSKGALTTLDTLRRI
RDELGGRSILGVSNISFGLPQREIINAAFFTMAMEAGLNAAIINPNSEAMMRAFYSFNALMDRDAQCSQYIGVYSGQSAG------LGQTIG--KGGDCS
LSAAIERGLKDAAHQAVTALLEEK-EPLGIINEQMIPALDRVGKGFEKGTIFLPQLLMSAEAAKAAFEVIKTKMDAKGQQEKKGTIVLATVKGDIHDIGK
NIVKVLLENYGYEVVDLGKDVPPERIVEETMGRKVQLVGLSALMTTTVPSMEETIRRLRTAAPWARVMVGGAVLTEEYARTIDADMYCRDAMASVNYAES
IFV
>tr|B1B9Q9|B1B9Q9_CLOBO 5-methyltetrahydrofolate--homocysteine methyltransferase OX=445337 OS=Clostridium botulinum C str. Eklund. GN=CBC_A0640 PE=4 SV=1
-MDIRNYIKN-NILIFDGAMGTMLQKSGLKLGETPEKLNFSHEELIIDIHKKYINAGCNIITTNTFGANEIKLKNPFSVENTITKAVSIAKKASEN-CFI
ALDIGPIGKLLEPMGTVKFEEAINIFKKQIKVGVECGVDLILIETMTDLYELKAAIIAAKEISDLPIFATMSFENGRTFTGCLPESMSITLEALGVDALG
VNCSLGPKELKPIVKKIIEHTNLPVIVQPNAGIPSI-VKGKTLYTISPKEFCNYVEALIDIGVSIIGGCCGTTPEFIKHLKYICNHKKILKRSP--IKKS
FVTTPSKIVELN---EVRIIGEKINPTGKKRLKEALINNDIDYILKQAIDEVDRGADILDINVGLPEINEADTLEYTLKKIQCIVDTPLQIDSSNVEAIE
RALRIYNGKPIVNSVNGEDKSLENILPLVKKYGASVIGLTLDNKGIPKTASERFKIAERILNTALDYGIKKEDIYIDCLTLTVSAQQNEVMETLKALKMV
KERLGVKTVLGISNISFGLPNRDIINETFLSLALGSGLDLPIMNPTKQGMINIINAYKVLNNNDKNAKNYIETYRNSTSN-----TQINSKL--E-EHTN
LEEFILQGLKNNTKNLTCDLLKTN-TELEIVNKFLIPALDNIGTKYENGEIFLPQLIQSAETVKVAFELIKENLLKSRKAVSKGKIILATVKGDIHDIGK
NIVKVILENYGYEILDLGKDVSSKKIVKEAIDKNIKLVGLSALMTTTIKSMEDTIIALKNANFEGKIMVAGAVLTKEYAIKMGADFYAKDAKDSIEIAKK
IFN
>tr|A8SDR3|A8SDR3_9FIRM Putative 5-methyltetrahydrofolate--homocysteine methyltransferase OX=411485 OS=Faecalibacterium prausnitzii M21/2. GN= PE=4 SV=1
---MNELFQS-NTILLDGGMGTMLQAAGLKLGARPEELNITDPALIEGIHGQYAAAGSRIVNANTFGASAHKLAGTYTLEQVITAGIENCKRACAP-ALT
ALDVGPLGELLEPSGTLAFEDAVAEYARIVKAGEAAGADLIFFETYTDLYELKAALLAAKENTRLPILASMSFEGGRTFTGCTVESFAATARGLGADAVG
INCSLGPKEIFPMAKRLAEAVNFPVFVKPNAGLPRA-DGS--GYDITPQLFALQMKPYRELHLFAAGGCCGTTPEFIKLLNGTFAGCTPGRPAH--RMPS
VLCTPVDTVTVD---GITVVGERINPTGKKRFQQALREGDMNYVLEQAVSQAEAGAQILDVNVGAPGVDEPVLMEQVVKALQSVTSLPLQLDSSNVEALA
RGLRVYNGKPIVNSTNGEPEKLAAILPLCKKYGAAIVGLAIDEKGIQPKAADRVAIARRITEAALAAGIPREDIYIDCLTLTASAQQEDVLATVQALEAC
KKELGVRTVLGVSNISFGLPCRTYLNTTFLTMAMYAGLDLAIMNPSSEEMMAAVYAYNVLTNRDKQSTKYIERFADALAQ-----AAKAAPA--A-SAAE
LMKAVEKGLKGDAAAHTRALLAEK-QPLEVVDEALIPALDIVGAKYEKGTLFLPQLLQAASAAQSAFEEIKTAIAQKGGSASKGRIVLATVKGDVHDIGK
NIVRVILENYGFEVLDLGRDVPVETVVDTVREKDVHLVGLSALMTTTLKSMEETIAALRAAKLDCKIMVGGAVLTPEYAEKIGADWYAKDAKRSADIAKE
FFG
>tr|A7AYB8|A7AYB8_RUMGN Putative 5-methyltetrahydrofolate--homocysteine methyltransferase OX=411470 OS=Ruminococcus gnavus ATCC 29149. GN= PE=4 SV=1
-M-ILERLGK-ELLFFDGGMGTLLQAKGLLPGELPETWNLTHAEAVRQIHRSYFEAGSDIVLTNTFGANALKFHDSCSLKEIIFSAVSHVKEAAKQEVYT
ALDIGPTGKLLKPMGDLEFETAYEAFKEVMIYGEQAGADLIHIETMSDTYELKAAVLAAKENTTLPVFVTTIFDRGKLLTGADVPSVVALLEGLRVDALG
INCGMGPEQMMPILHEILEYTSLPVIVKPNAGLPKQ-RDGETYYDVEPEQFAKTMEMIVETGACVIGGCCGTTPDHIRAMIAQCKDLLIKTPEK--KVHT
IVSSYGQAVMLGT--GSRIIGERINPTGKKKFKQALKDHDLDYILKEGIMQQDNGAHILDVNVGLPDIDEVSMMKEVITELQSVTSLPLQIDTVDIQAME
QAMRIYNGKSMVNSVSGKQESMDAVFPLIQKYGGVVIGLTLDEDGIPETADGRVAIAEKIIREAAKYGIDKKDLVIDVLAMTVSSEPEGAKITLEALHRV
RYDLGVNTVLGVSNISFGLPGRPIINANFYTMAMFQGLSAGIINPASEDMMRSYYAYHVLMNLDPNCENYIGRYGSANVE------FASAPG--SIGMMT
LQAAIEKGLKEEAHQITNVLMQEK-KPLDIINEHLIPALDTVGKGFEKGTVFLPQLLMSAEAAKTAFAVLKEGLENSGDQEKKEKIVLATVKGDIHDIGK
NIVKVLLENYSFEVVDLGKDVPPETIVDTVVAQQIRLVGLSALMTTTVVSMEETIRQLREKAPWCKVMVGGAVLNQEYADMIGADFYGKDAMQSVYYAQG
LLQ
>tr|L0K7J3|L0K7J3_9FIRM Homocysteine S-methyltransferase/B12 binding domain/Pterin binding enzyme OX=748449 OS=Halobacteroides halobius DSM 5150. GN=Halha_1312 PE=4 SV=1
-SSIVDRLEE-EILVLDGAMGTELQKRGLEVGDCPEELNLTHPKILKEIHSSYVKAGSDIIQTNTFGANRLKLAENLKIEKINQQAVKLATEVAGDF--I
SASIGPTGKLLEPLGDLSFQQAYHVFGEQAQILEAAGADLINIETMTDLQEARAALIAVKEKTSLPVIINLTYENLKTMTGTDPQTAITVFEALGADVIG
ANCSLGPKKLVEIIKLMGQYTATPLCVQPNAGLPVL-NNNETIFPMEALEMANYIPQFIEAGVNIIGGCCGSTPEYINLAKKKVVDITPASRIKK-KE-T
TLASRTKRVVISDNLPTRIIGERINPTGREELSHQLADEKMELVAKEASNQVQAGADILDVNVGVPQIDQAQAMKLALNTVHNVVDIPVSIDTTNQEVLE
AGLQTIVGKPLINSVTGEEESLNTVLPLAKKYGAAVLGLTLDEDGIPATAQGRLKVAKKILNRAQQLGIKRENVLIDTLTLAASAEQDKVLETIKAIELI
KEELGLATVLGVSNISYGLPAREEVNTAFLAMAIQAGLNAPILDPTNKAMQATLKASDLLVNRDLQGQNYL---NHYSQE-----ERKEKEK--LEDSLT
LYHLVLEGDKDNIISEIEQAL-TDHQALEIINQALIPGIKEVGAKYDEGTYFLPQLMMSAETMQEAFTKLRPIL--QEEQQTIGRVLLATVKGDIHDIGK
NIVKVMLENNGFEIIDLGKDVANDKIITKAIEQEVDLVGLSALMTTTMPNMEKITMILKEKAPEIKILLGGAVVTRDYANNIGADGYAQNAVEAVKKATE
LIN
>tr|D1NM92|D1NM92_CLOTM Homocysteine S-methyltransferase OX=492476 OS=Clostridium thermocellum JW20. GN=Cther_2030 PE=4 SV=1
-MDFLDFLNQ-NILILDGATGTELQKRGMPGGVCPEMWVIENPDVIMDIQKDYINAGSNAVYTCTFGGNRIKLSEGLKVVEINKKLAQLSRKAAGEKGLV
AGDLAPTGRFVRPFGDMPFEEAVDVYKEQVKGLLEGGVDFFVIETMMDIQEARAALLAVKESCDLPVCVSMTFDSGRTLTGTDSVSALIILQSLGADVVG
CNCSTGPQDMIKIIREMKPYAKVPLLAKPNAGLPKL-IDGKTRFDMEPEEFGSYIKEFVEAGVNLLGGCCGTSPVYIEQIRKNIEGLKPIPPQP--KEIC
AVASARKTVFVDANEPVVVVGERINPTGKKKLQEELRQGMTSLVRQFAVEQVEKGADILDVNVGMPGIDEKETMVKVVELLSSITDAPLCLDSSSPEVLE
AALRIYPGRALINSISAEKVKIEKLLPIAAKYGAAFILLPLGDAGVPKSAGERCKIVEEVFNEASKWGYTKKDVIVDGLVMTVSADQEAAVETLKVIEWC
TQSFGCGTIVGLSNVSFGMPERAWINSAFLAMAIGYGLTMAILNPSSDTLMSIKMASDVLKVKDRNSKKYIEHFKS-VVE-----KKDTASP--V----E
VYDAVVKGDRENIRKYIDDALKDGTEPSIIVDKYLIPAITHVGDLYDRKEYFLPQLIQSAETMKEAFGILEPLLKKEPVDEKKVKVILATVKGDIHDIGK
NIVGLMLRNYGFEVYDLGKDVSAEEIVKKAKETNAPIIGLSALMTTTMLEMREVVSLVRQEGLNAKIMIGGAVVNADYAKEIGADGYSEDAYGAVKLASK
LAG
>tr|Q8R927|Q8R927_THETN Methionine synthase I, cobalamin-binding domain protein OX=273068 OS=100824 / MB4) (Caldanaerobacter subterraneus subsp. tengcongensis). GN= PE=4 SV=1
-VDIFKECEN-RVVVFDGAMGTQLQERGLKAGECPEYINLKMPEVVFDIHKAYIEAGAEVIETNTFGANRIKLAKGLEDKEIVTKGVEIARKAAGD---V
ALSVGPTGELLAPFGDMTFDEAYEVFKEVVVAAEKAGADIVIIETMSDMLEAKAAILAAKENTNMKVICTMTFQDGRTLMGSDPVTVVVSLQGLGLDAIG
VNCSTGPDKMVKVVEKMAQVARIPIIAQPNAGMPVI-RDGKTVYDLKPEEFASFFPQLVEKGACIVGGCCGTTPYYIKLVKKAVENLKPKKLEN---KFT
ALSSNTRTVFIGKEYPLRVIGERINPTGKKKLSGALLSGDVNLAVEEALKQQKCGAEILDVNVGVPGIEEEEMLPKVAFEVEKAVDLPLQLDSTNVKAIE
KAIRILRGRPIINSVNAKEESLKEVLPIVKKYGACVVGLTVGDKGLPKDRHERVENARKILKKAEEYGIPKEDVIIDPVVLTVSSEQGAAIETLEAMKII
SEELGVNTVVGLSNISFGLPERKLINSTFLAMAASHGLTAAIVNPCDESLMDTLRASMVLLNKDKGSENYLKVYGQRVKP-----K--EVIK--R-HEED
FSKKILEGKKSGVEEIVMALLEDN-PPLSLVDEIIIPALKEVGDRYEKGIYFLPQLLSSAEVVQSAFKLIKEKL----KTASKGKIILATVEGDVHDIGK
NIVKVLLENYGYEVIDLGKDVKGEVIVEEVKKTGAPLVGLSALMTTTLFNMEKIIKMLKENT-EAKVMVGGAVLTEEYAFKIGADYYGKTAQDAVKIADK
FF-
>tr|B2UWX6|B2UWX6_CLOBA 5-methyltetrahydrofolate--homocysteine methyltransferase OX=508767 OS=Clostridium botulinum (strain Alaska E43 / Type E3). GN= PE=4 SV=1
-MGLREFIKD-NILVFDGAMGTMLQKEGLKLGENPEIFNIEESEKVKNVHKKYIENGAMVVTTNTFGANELKLDNKYTVEEIIDAAISIAKGAREN-IYI
ALDIGPIGELLEPMGTLSFERAYDIFKRQMIQGEKSGADLILIETMTDLYEAKAALLAAKENTKLPVFCTMSFDSGRTFTGCTPESMALTLGGMGADAIG
INCSLGPKELLPIVKRIKKATNLPIMTQPNAGLPKL-SFGEAIYDIMPEEFKYWVNEFIKEGVSIIGGCCGTNPEFIKELRLLADSNKRLRREN--IEFS
AVCTPSKVVKIE---GVKIIGERINPTGKKLFKEALKNNDIDYILKQAIEQVEAGADILDVNVGLPEINEKEMMKKVVKEIQGIIDTPLQIDSSNIEAVE
AGLRTYNGKPIVNSVNGEDEVLEKVLPLVKKYGASVVGLTLDKKGIPATADERFKIAEKIVKKAKEYGIEKHDVFIDCLVLTASAQQAEVKETLKALRKV
KEELGVKTLLGVSNISFGLPCRELINETFLAMAIANGLDLPIMNPNSTGMMDVINSYNVLTNIDKGCERYISIYGNENKS-----DKNEETQ--S-NNSD
LRYIVIKGLKDEAEEATKNILESM-NELDVVNEILIPSLDEVGLKYEKGEIFLPQLIQCAETVKKSFEVIKKNIVINKENISKGKIVLATVKGDIHDIGK
NIVKVILENYGYEIIDLGKDVPIETVVDAVLKNDIRLVGLSALMTTTLKSMKETIKALKDNGYSGKTFVGGAVLTSEYAKEICADYYAKDAKESVEIAKK
ILG
>tr|C4IKP6|C4IKP6_CLOBU Homocysteine S-methyltransferase OX=632245 OS=Clostridium butyricum E4 str. BoNT E BL5262. GN=CLP_1226 PE=4 SV=1
-MGLKELIKE-KILIFDGAMGTMLQKKGLKIGENPEILNIKSPDIIEEIHREYIESGANVITTNTFGANERKLKLNLEVEEAVDAAINIAKKARGE-VYI
ALDIGPIGELLEPMGTLSFDEAYDIFKRQIIQGTKSGADVILFETMTDLYELKAAVLAAKENSSLPILCTMTFENGRTFTGCLPEAMVLVLEGLGVDALG
VNCSLGPKQLKPVVEEICRLSNIPVMVQPNAGLPTL-SVNETKYDVTKEEFAETLCSFIDSGVSIIGGCCGTTPDYIRELVKQTDGKSILKREK--NYYP
AVCTPSKVVKID---GIRIVGERINPTGKKLFKQALINDDLDYILNTAVAQTEAGAHILDVNVGLPEINEPEMMQKVVKEIQGILDIPLQIDSSDKNAIE
KGLRYYNGKPILNSVNGEDKVLENILPMVKKYGANVVGLTLSESGIPKKAEERFEIAKKIVDKAAQYGINKENVFIDCLVLTVSAQQEEVQETLKAVRMV
KEKLGVKTLLGVSNISFGLPNRKLINETFLALALANGLDLPIMNPNESGMVRVIDSYNVLYNYDKGSEHYIKNYANDKTN-----IIKSQSE--N-GESN
LKSIVIKGLKEEAKSATTNLLKKY-EPLTIVNEYLIPALDEVGDKYEKGVLFLPQLIQAAETVKNSFAVLKAEISKNNETISKGKIIVATVKGDIHDIGK
NIVKVILENYGYEMIDLGKDVPIETVVSEAKKHNVKLIGLSALMTTTLRSMEETIKALKEDGYEGKVFVGGAVLTPEYADAIGADFYAKDARESVEIAKE
VLS
>tr|C0WB71|C0WB71_9FIRM Putative uncharacterized protein OX=563191 OS=Acidaminococcus sp. D21. GN=ACDG_00712 PE=4 SV=1
-M-IRERLEK-ERLFFDGGMGTMLQSAGLMPGELPELWNLSHADVIQGVHEAYIRAGAQIIKTNTFGCNGLKFGKTPAVSTLVTAAVKLAQKAFQAKGCV
ALDLGPTGKLLQPYGDLPFEEAVSLYAEAVEAGKKAGADLVLIETMSDTYEAKAAILAVKEHSNLPFVVTFTFDEGKLLSGADVETAMIVASSLGASAVG
FNCGLGPKEISRLVPRALAATDLPLVVNPNAGLPVT-HDGVTQFEVGSEEFAATMLEFAPQ-TALLGGCCGTTPQHIKALVESCAELPPPEKRN--GAPE
CITGYGAPVCFDR--MPVIIGERINPTGKKRLKEALKAGDMDYVCQLALEQIDKGAQVLDVNVGVPGIDEPALLEKAMRTLQSITPLPLQIDTSDLKAME
RALRLYNGRPLLNSVNGKTSSLSSVLPLAKKYGAMLVGLCLDDDGIAESLEGRLKSARRVIDGAKKAGLSEKALLLDPLAMTISTGGQNAQIALSIIAAL
KKA-GLKTVMGVSNISFGLPHRDAVNSAFFASAMQLGLSAGIINPNSAPMMETYLAYGALSGYDTSCKAYVSYFADLPTEK-----REPHVP--AAGRYG
LDEAIEKGLISPAETAVAALLDEG-RDLSIINEYMIPALNRVGDAFEKKTLFLPQLLMSADAAKAGFEIIKKAMFQKGARGKGDPVIVATVKGDIHDIGK
NIVKVLLENYGYDVIDLGKDVPPEAIVEKTLERDVKLVGLSALMTTTLGSMAETIRQLREKAPGCRVIVGGAVMTKEYAEELGADAYAGNAVAAVSYANA
LFR
>tr|G8LVZ9|G8LVZ9_CLOCD Homocysteine S-methyltransferase/B12 binding domain/Pterin binding enzyme OX=720554 OS=Clostridium clariflavum (strain DSM 19732 / NBRC 101661 / EBR45). GN= PE=4 SV=1
-MQFLEFLKE-NIMILDGATGTELQKRGMPKGVCPEKWVIENPDVILDVQREYVSAGSNAVYTCTFGANRIKLEAGLKVVEMNAELARLSKKAVGDKAFV
AGDLAPTGKFIKPFGDMDFETCVEVYKEQVKGLLEGGVDFFVIETMMDIQEARAALIAVKESCDLPVCVSMTFESGKTLMGTDPLTALITLQSLGADAVG
CNCSTGPKAMIEIIRAMKPYALVPLLAKPNAGLPKL-VDGKTVFDMGVEEYGTYVEELVKSGVNLLGGCCGTSPLYIAEIKKNLKGLKPLKIEP--EKVS
AITSARSTVFLGTNQPTVVVGERINPTGKKKLQEELKEGKTSLVTDLALEQVEKGAKVLDVNVGMPGIDEKETMVKIVELLVSMVSTPLCLDSSSPEVLE
AALRIYPGRALINSISAEKAKLEKLLPVAAKYGAMFILLPLSDEGVPATAEERYTIINEVYERAKKYGYEKKDIVIDGLVMTVASDQKAALETLKVIDWS
TNTFGCNTILGLSNVSFGLPERSWVNSAFLAMAMGKGLTMAILNPSSDTLMSIKMAGDVLTGKDKNSLKYIEYFTK-VQT-----KKAEQSV--T----E
IYGAVVGGDRENIKLHIETALKEGYEASYLVDNCLIPAINHVGDLYDKKEYFLPQLIQSAETMKEAFGLVEPLLKKDETAEKKARIVIATVKGDIHDIGK
NIVALMLRNYGFEVYDLGKDVPAEEIINAAKEKKAEIIGLSALMTTTMMEMKTVIELAKKEGLKAKFMVGGAVVTESFAKEIGADGYSEDAYSAVKLANK
LLE
>tr|D4JC64|D4JC64_9FIRM Methionine synthase (B12-dependent) OX=717962 OS=Coprococcus catus GD/7. GN=CC1_34090 PE=4 SV=1
-MEFQRLCRE-RIVFLDGATGTNLQKAGMPTGVCPEAWILEHPDTMMQLQKAYFEAGSDIVLAPTFTANRIKLDEGLKIEEMNHQLVAISKAAAGDRGLV
AGDMTMTGRQLAPMGDMGFEELIDIYKEQAGYLVDAGVDLFVVETMMSLNECRAALIAIREVTDLPVCVTLSFNDGRTLFGTDACTAMVVLQSLGADAVG
INCSTGPEQMAELVREMKAYANIPIIAKPNDGMPEV-IDGETVYRMTPEEFAAEARLLLEAGAGIVGGCCGTTPEHIRAFKEAAKAYPVPEVSQ--TYKR
VLASERQTLEIGLDAGFKIVGERINPTGKKKLQAALREGQMDMVMDMALAQEEKGASILDVNMGMNGIDEKAMMLKSIEIVTQAVNLPLCIDSSHVDIIE
AALRVYPGRALINSISLEKEKFEHLLPIARKYGAMFILLPLSDEGLPKNIDEKIQIIHTIMDRALELGFHKEDIVVDGLVATIGANKNAAIETLDTISYC
HDQLELATICGLSNISFGLPERSYVNTAFLTMAISRGLTMAIANPSQDLLMHAAFASDLLMNHPGADIRYINRM---AVK-----EQQSGES--TAAVVE
IFEAVMKGSQGSIINLVKEGLDAGIMPDDMIQKHLITAIQKVGVLFEEKKYYLPQLIASAETMEKAINYLEPMLIKDDE-EEKATIIMATVEGDIHDIGK
NLVVLMLKNYGYRVIDLGKDVSAECIIETAVKEHAAIIGLSALMTTTMMRMRDVVELAQAKHCSSKIIIGGAVTTQSFADEIGADGYSRDAAEAVHLVER
LLN
>tr|I3VV59|I3VV59_THESW Homocysteine S-methyltransferase OX=1094508 OS=Thermoanaerobacterium saccharolyticum (strain DSM 8691 / JW/SL-YS485). GN= PE=4 SV=1
-MDIFENLKN-SAIVFDGAMGTMLQKKGLKTGECPEYYNLSHPDIVYEIHKSYIDAGADVIETNTFGANRIKLKSNLSDKEIVKSAVQIARKAAGD---V
ALSIGPIGELMEPFGKLTFDEAYSAFAEVAVEGEKAGADLALIETMSDILEAKAAILAVKENTNLKAICTMTFQDGRTLMGTDPVTAVVSLQGLGLDAIG
VNCSTGPDMMADIVKKMAEVSRIPILAQPNAGMPHL-EDGKTLYDITKEQFAVETKKLLECGASIVGGCCGTTPEFIKLLKAEVHGTEKDSIVK---KYT
AVSSNTKTIFIGSDYPVCIIGERINPTGKKKLSAAIREGNFNLIYDEALSQEKLGASVLDVNIGVPGINEEELMPKIISQVQNIVNVPLQIDSSNVRAIE
KAVRVVRGKPIINSVSAKEKSLQEVLPIVKKYGTSVIGLTISDDGLPKNADERLKNAEKIVKAALDYGIPKEDIIIDCIALTVSSEQTAAMETLRAINLV
KSKLGVSTVIGLSNISYGLPERQFINTAFLAMAVSYGLDAVIVNPNDKITMDILNASMVLSSRDKRCERYINTYKKDDGN-----KPVSVEK--K-TDVN
ASDMILEGKKADIDRLVLEILNEGVEPLSIVDNTVIPALKDVGDKYDKGIYFLPQLLNSAEVVESAFKVLKEKM----KMGSKGKIILATVEGDIHDIGK
NIVKVLLENYGYEVIDLGKDVKPSIIVDEVKRTNAKLVGLSALMTTTLNNMEKTIEVLRNIK-DIKIMVGGAVLTKDYALKIGADYYGANAQEAVRIADK
VF-
>tr|D9TM15|D9TM15_THETC Homocysteine S-methyltransferase OX=580327 OS=571 / NCIB 9385 / NCA 3814) (Clostridium thermosaccharolyticum). GN= PE=4 SV=1
-MDILKNLKN-SVIVFDGAMGTMLQMKGLKTGECPEYYNITHPDIVYEIHKSYIDAGADVIETNTFGANRIKLKANLSGDLIVRSAVKIAKKAAGD---V
ALSMGPIGELMEPFGKLTFDEAYNAFSEVAVEGEKAGADLALIETMSDILEAKAAILAVKENTNLKVICTMTFQDGRTLMGTDPVTAVVSLQGLGLDAIG
VNCSTGPDMMADIVKKMSEVARIPILAQPNAGMPHL-KDGKTFYNVSPEQFVHQSKKLLECGASIVGGCCGTTPEFIKLLKNDVYNVEHKSTMR---KVT
AVSSNTKTVFIGENNPICIIGERINPTGKKRLSAAIKEGKFNILFDEASSQENLGADMLDINIGVPGIDEEKLMPYVVSQIQNIVNLPLQIDSSNVKAIE
NAVRIVRGKPIINSVSAKEKSLQEVLPIVKKYGTNVIGLTISDEGLPRNAEERLKNAEKIVKTAFDYGIPKEDIIIDCIALTVSSEQTAAIETLKAIKLV
KSELGVSTIIGLSNISYGLPERQLINTAFLAMAASYGLDAVIVNPNDKITMDILNASMVLTSRDARCEKYIQTYKKDDKS-----NSDTIEE--K-LKKD
ASQMILEGKKADIDRLVLEILNEGVEPLSIVDNTIIPALKDVGDKYDKGIYFLPQLLNSAEVVESAFKVLKEKM----KMGSKGKIILATVEGDIHDIGK
NIVKVLLENYGYEVIDLGKDVKPSTIVDELKRTKAPLVGLSALMTTTLNNMEKTIKILRKEH-DVKIMVGGAVLTKDYAMKIGADYYGANAQEAVRIADK
VF-
>tr|C8W2L3|C8W2L3_DESAS Homocysteine S-methyltransferase OX=485916 OS=B-1644). GN= PE=4 SV=1
-MRFIDKLAE-KILVFDGAMGTMLQAAGLRAGECPELINLKNPETVKNIHRQYVKAGADIVETNTFGGSRLKLLEGLKVAEINASAVRLAKESADQL--V
ALSVGPTGKLMFPNGPLTFDEAHHVFSEQISAGAAAGADMICIETMSDLGEIRAALLAAKDAAPVPVICSMTFENKRTLMGTDPVAAVITLQALGADIIG
ANCSGGPGELLEVIEEMARYARVPLIVQPNAGMPML-EGDRTVFPLSAAEMGEYVPKLAAAGASLIGGCCGTSPEYIRVIKERSTGLKPLPRNIT-PV-T
AITSARQTLFIGSGHPVRIVGERINPTGRKELSEQLRKGDMSLILREAVEQVERGANLLDVNMGLPEIDEAALMEKAVNSLQKVISVPLQLDSTDPKVLE
AGLKAYHGKAIINSVNGKEESLKTILPLAKRYGACILGLALDDKGIPKTSEGRLAAAEKIMQRALALGIPKEDIIIDSLVLTASAQQDTALACVECTRLV
KEELGLSALLGVTNISYGLPNRSLIDNTFLAMCLAGGVDVVIFNVENQDMVNTVRASEVLTARDKHSRNYINLFAAGEQG-----AVLEAVE--DR-PAD
LYRDIINGFKENTVPLLEEVLKQGMMPLQIVDDLLVPALDEVGGKYDRGEFFLPQLMQSAEVVQAAFARLKQEL--KVADSGKGTVLLATVKGDIHDIGK
NIVKVLLENYGYEVVDMGKDVPPEEIVRAAKEKDIRLIGLSALMTTTVVFMKETIDLLRQEKPDCKVVVGGAVLNEKYAENIRADFYARDAREGVAVARE
VFG
>tr|C4Z1L6|C4Z1L6_EUBE2 5-methyltetrahydrofolate--homocysteine methyltransferase OX=515620 OS=Eubacterium eligens (strain ATCC 27750 / VPI C15-48). GN= PE=4 SV=1
-MAFRELLNR-DYIIFDGAMGTMLQAAGMKMGETPEVLNITRPELLVSIAEQYFNAGSDVVYANTFGANRYKLEEGKSVEELVTAGIVNAKKARDA-GLV
ALDVGPIGQLLEPTGVLSFEEAYDMYAEIVKAGAAAGADLVVFETMTDLLDVKAAVLAAKENSDLPIAATMTFENMRTFTGCSISAMALTLTGLGVDALG
VNCSLGPKELEPVIEELVKWTNLPIIVKPNAGLPDP-ETN--LYNVTAVQFADFMKDLRKYGIKIFGGCCGTNPEFIKELSEMLEGNPAAPHK---YIPG
AVCSATSTVVVD---EPRIIGERINPTGKKLFKEALLRHDMDYILGQALEQISGGADILDVNVGLPGIDEREMMIDTIKSLQAVVDVPLQIDSTIPEVLE
AALRVYNGKPLVNSVNGEEESLNNVLPLVKKYGAGVIGLALDKDGIPKKAEDRVAIAKKIMDRAVAMGIPKEDIYIDCLTLTASAEQEGVMETLNALHTV
KNELGLKTVLGVSNISFGLPNRVLVNHIFLTMALTNGLDLAIINPNIPEMTGAVRAYKLLANIDKNSVDYIKNYGA---D-----PVKKEKK--D-GNY-
LFYAVEKGLKNEGAEITEALLKTM-DSMEIVNQVLIPALDKIGAEFEKGTLFLPQLIMAASVTQAAFEVIRKHMVMSDAPVSKGKIVIATVKGDVHDIGK
NIVKVLLENYGYDVIDLGKDVEYQTVVDAIRDNDVKLCGLSALMTTTLVSMKETIALIRENNLDCKVMVGGAVLTPEYAKEIDADFYAKDAKESVDIAKR
VLG
>tr|B9E0A6|B9E0A6_CLOK1 Uncharacterized protein OX=583346 OS=Clostridium kluyveri (strain NBRC 12016). GN= PE=4 SV=1
-MNFKNLVNN-RFIFFDGAMGTMLQKAGLKLGELPEVLNITNPEIISGIHRKYLDAGADIITTNTFGANELKYDSDYTIEDVISAGVKLAKQEAGD--LV
ALDIGPIGKIMEPTGNLSFESAYKLFKNQIVIGEKSGADVVLIETMTDLYEAKAAVLAAKENSNIPIFCTMTFQDGRTLMGTDAKTMVFVLEALGVDVLG
VNCSLGPKELQGIVEEILKYSSIPVMVQPNAGLPRY-DGENTIYDISPEDFAENVLTMAQKGIRVLGGCCGTTPEFIRMCRKDLEGLTPLNIEE--KHYT
AVCSATDTVIVE---KIKIIGERINPTGRSIYKKELKEGSINYIQKEAIMQKEEGANILGVNVGLPEINEVEIMKKAIRAVQKVVQLPLSIDSPDPQVLE
TGIRMYNGKPVINSVNGSKKSMEEVFPIVKKYGGCVIALTIDEKGIPHTAEGRVKIAEKIIKTASIYGINKKNIIIDCLTLTVSAQQKEVLETIKAIKMV
TEKFGVKTVLGVSNISFGLPNRSILNRTFLAMALQAGLNLPIMNPADESMKEVIAAFQVLTNIDKEGKEYVIKYGNKSKD-----EKPKNAD--N-NLKD
LKQLIIDGIEDEAEAMTTELLKNK-KALEIVNSYIIPALDEVGKQYELQDIFLPQLIQSAETVKKSFEIIKDNMLSSGKSLEKGTIVLATVKGDIHDIGK
NIVKVLLENYGFEVIDLGRDVDIDNIVNTIRDNNIKLVGLSALMTTTVASMKKTIEAIRENNLNCKIVVGGAVLNQNYADMIGADYYAKDAREAVKIAEE
VFL
>tr|A6LTA0|A6LTA0_CLOB8 Homocysteine S-methyltransferase OX=290402 OS=acetobutylicum). GN= PE=4 SV=1
-MGLREYIKN-NILIFDGAMGTMLQKKGLKLGENPEILNLKEPYIIEEIHREYISSGANVITTNTFGANELKLKLGLVVEEAIDAAVNIAKKTKGN-TYI
ALDVGPIGELLETMGTLSFDRAYEIFKRQIIQGVKSGVDIILIETMTDLYELKAAVLAAKENSSLPIFCTMTFENLRTFTGCTPEAMVLVLEGLGVDALG
VNCSLGPKQLKPIVEKICSLSHIPVMVQPNAGLPTL-SIGETKYDVTKEEFADTLCGFIDLGVRVIGGCCGTSPEYIEELYKITRNKKLVFMEK--EYYS
AVCTPSKVVRID---GVRIIGERINPTGKKIFKEALKNGDLDYILNQAVSQIEVGAHILDVNVGLPEIDEADMMHKVIREIQGIMDTPLQIDSSDHKAIE
TGLRYYNGKPILNSVNGEDEVLDRILPIVKKYGASVVGLTLDERGIPAKAEERFEIAEKIISKAAEYGIRKEDVFIDCLVLTVSAQQKEVQETLKAVRMV
KEKLGVKTVLGVSNISFGLPNRELINETFLVLALANGLDLPIINPNVNGMTRVIDSYNVLYNYDKGAESYINNYAN-NGA-----AKINSNI--N-TVHD
LKYIVVKGLKEEAKQATVELLKEK-KELEIVNEYLIPALDMVGEKYEKGELFLPQLIQAAETVKNSFTILKEEISRTNQTISKGKIIVATVKGDIHDIGK
NIVKVILENYGYEMIDLGKDVPIKTVVEEAKKHNASLIGLSALMTTTLKSMEETIKALREDGYNGKIFVGGAVLTKDTAERIGADFYAKDAKESVEIARR
VLS
>tr|L1QEJ5|L1QEJ5_9CLOT Putative 5-methyltetrahydrofolate--homocysteine methyltransferase OX=545697 OS=Clostridium celatum DSM 1785. GN=HMPREF0216_02149 PE=4 SV=1
-VGVKELINK-ELILFDGAMGTMLQKNGLKLGENPEKLNFSHEDMIIKIHKSYIDSGANIITTNTFGANRLKLKEGYSVEETISKAVSLAKEATKD-AFI
ALDIGPIGELLEPMGTLSFDEAYEIFKEQIIIGHKAGADLILIETMTDLYEAKAAILAAKENCNLPVFCTMSFEDGRTFTGCLPSSMAITLEGLGVDALG
VNCSLGPDKILKVIKEIKKYTNLPLMVQPNAGLPSI-IFGEAIYDISIEDFTEGIEELINEGVSIIGGCCGTTPEFISSIRLLINSKEIISRPK--VSFT
AVCSPSKFIEIN---GVEVIGERINPTGKKLFKEALKNNDMNYILKQGIEQVEAGASILDVNVGLPEIDEVKWIRDSVKSLQGILDTPLQIDSTNVDAVE
AGLRYYNGKAIVNSVNGDDEILDKLLPIVKKYGAAVVGLTLDKEGIPALAEERFKIAEKIFNRAISYGIKKEDIFIDTLVMPVSADGQSAKETLKALRLI
REKLGLKTVLGVSNISFGLPSREIINKTFLSLALEEGLNLPIMNPNSEAMMEVIDSFKLLYNYDKKGSKFLEKYGN-KIK-----KEVVAEN--K-NNSG
LSELIIKGLKKEAQTVTKELLKEN-EPIDVINKHIIPALNIVGERFEKGQIFLPQLISSAETVQSSFEILKNNIKISD-NINSEKIILATVKGDIHDIGK
NIVKVMLESYGFQVIDLGKNVDKEEVLNCAKEQNVKLIGLSALMTTTVKSMEETIQLLKINDLNAKIMVGGAVLTEEYAKEINADYYAKDAMESVKIAKE
YFA
>tr|G1WMG2|G1WMG2_9FIRM Putative uncharacterized protein OX=742765 OS=Dorea formicigenerans 4_6_53AFAA. GN=HMPREF9457_00313 PE=4 SV=1
-M-ILDRLGK-ELIYFDGGTGTLLQERGLKPGELPETWSLERADDMIDIARQYYEAGSDIVLSNTFGANALKFHDRHKLDEIVKAAIENVRKGAKLETYV
GLDIGPTGKLLKPMGDLDFEDAYQAFAEVARLGEEAGADLIHIETMSDTYEVKTAVLAAKENTSLPVFATMIFDKGKLLTGGDVPSVVAMLEGLRVDALG
INCGMGPEQMMPILDEILQYASVPVIVKPNAGLPKQ-KDGEVYYDVEPEEFGRFMAEILKRGASLIGGCCGTTPAHIRAMVEATKDQRDITKEF--MNRT
IVSSYGRAVELGG--KPMIIGERINPTGKKKFKQALKDHDIDYILREAISQQDAGAHILDVNVGLPDIDEPALMREVVQELQSVTSLPLQIDTVDISALE
AAMRIYNGKPMVNSVNGKKSSMDAVFPLIQKYGGVVVGLTLDEDGIPATAEGRVKVAGKIIEEAKKYGIDKKDIVIDVLCMTISSEPTGAITTLEALRQV
REKYGVCAVLGVSNISFGLPYRPAVNSNFYTMAMQSGLSAGIINPLSEDMMRSYYSFCALMNYDENCEKYIEQYGSQKVQ------AVTPAT--K-AEMT
LKTAIEKGLKEEAHHITAELVKDK-APLDIINEELIPALDQVGKGFEKGTVFLPQLLMSADAAKIAFAVLKDELARSGEEQAKDKVILATVKGDIHDIGK
NIVKVLLENYSFDVIDLGKDVPPEEIVETAIKEDVRLVGLSALMTTTVVSMEETIRQLRKKKPECKVMVGGAVLNQDYSDMIGADFYGKDAMQSVYYAQQ
LFG
>tr|A4J6L9|A4J6L9_DESRM Methionine synthase (B12-dependent) OX=349161 OS=Desulfotomaculum reducens (strain MI-1). GN= PE=4 SV=1
-MSFRKRVKK-EVLIIDGAMGTLLQQRGLPGGWCPEEWNLSHPEAVKEIHKLYLEAGADIITTNTFGAIQLKLADHLQVKEINQAAVKLAKEVAQGM--V
AGSVGPLGKFLQPLGTMTFEEAYQQFYEQCAAMVEAGVDLILFETFGDIGEMRAALIAAADAGDVPVVASFTFDTGRTFTGTDPETAAVVAERLGIAAIG
VNCSVGPRQLEGVVRKLTESTNLPVLVSPNAGMPEI-IGGKTVFRETPEIMAEYAQRFVDYGASILGGCCGTTPKHIQAIYQQVKKLKPKCRNKR-FG-L
RVASRVKTVTIQPSGVPVAIGERLNPTGKKALQAEIREGKTEITRRDALTQVQAGAEILDVNVGVGGVDQVAAMERAVQAVQVLVEAPLCIDSTDPTVIE
HALKLYHGKALINSVNGEENSIETILPLAKRYGAALIGLTLDDEGIPPTAAGRLAVARRLVERTEAMGIPRDDLMMDCLVLTVSAQPEGVPETLEAIRLV
KQKLQITTSLGVSNVSFGLPNRVLINAAFFAMALNAGLDAAILNPQDQRMMETLRASAVLTGRDVRAEKYI---EQQTNG-----SKMTGEM--KA-PLD
LYQAVLSGDKDNIVSYINEALKTGLSPMELLDKALIPGIEEVGRRYGAGIYFLPQLMMAGETMTKSFERLRPEL--AKGAKKAGTVVLATVKGDIHDIGK
NIVSVMLANHGFEVIDLGKNVANEEILRVAAEQKANIIGLSALMTTTMVHMQEIIKLVKEQGLNCKVMVGGAAVTEHYAREIGADGYAIDAVEAVNVAKK
LAS
>tr|F6DRQ1|F6DRQ1_DESRL Homocysteine S-methyltransferase OX=696281 OS=DL). GN= PE=4 SV=1
-MSFKDRVQR-EILIVDGAMGTLLQERGLPAGWCPEEWNVSHPEVIKEVHGLYLRAGADIITTNTFGAIPLKLEEDMRVREFNLAAGRLAREAAKGM--V
AGSVGPLGKFLQPLGTLSFDEAYQQFLVQCRALVEAEVDLILFETFGDIGEMRAALIAAADAGSVPVVASFTFDSGRTFTGTDPETAAVVAERLGVAAVG
VNCSVGPRQLEGVVRQLTRSTNLPVLISPNAGMPEI-VEGRTVFRETPEVLADYAARFVDYGASLLGGCCGTTPEHIKAISQAVKDLEIKTRNKS-FG-L
RVASRVKTVAIHPAGMPVAIGERLNPTGKKALQAEIKEGKTEITRRDALAQVEAGAEILDVNVGVGGVDPIAAMERAIHAVQVLVDAPLCIDSTDPAVIE
HALKLYHGKAIINSVNGEDQSMETILPLAKRYGAALIGLTLDERGIPPTAEERLAVAGKIVARAEEMGIPREDIMIDCLVLTVSAQPEGVPETLKAISLV
KQELGLATSLGVSNVSFGLPNRKLINSAFFAMALSAGLDAAILNPQEERMMETLRASAVLTGRDLRAEKYI---REQVAE-----APVQEDK--KA-PRE
LYRAVLSGDKDNIIRYIEEALGQGMGPLEMLDKALIPAIEEVGRRYAQGVYFLPQLIMAGETMTKSFECLRPAL--AKGTKKVATVVLATVKGDIHDIGK
NIVSVMLANHGFEVIDLGKNVDNQRIIEAVREHRAGLIGLSALMTTTMIHMPELIKDVKEAGLACKVMVGGAAVTAQYAKEIGADGYAEDAVEAVRIAKE
LIS
>tr|F6B728|F6B728_DESCC Methionine synthase OX=868595 OS=CO-1-SRB). GN= PE=4 SV=1
-MSFKDRVRK-EVLVIDGAMGTLLQQRGLPPGWCPEEWNVSHPEVVKEIHKLYLNVGADIITTNTFGAIKAKLADGMRVKEFNLAAVRLAQEVAHGM--V
AGSVGPLGKFLQPLGPLTFDEVYRQFLEQCQALVEAGVDLIILETFGDIGEMRAALIAAADAGDVPVVASFTFDTGRTFTGTDPETAAVVVERLGASAVG
VNCSVGPGQLEKVVQQLTQSTNLPVLVSPNAGMPEM-VDGRTVFRETPAVMADYAGRFVEYGASILGGCCGTTPEHIGAIHQRVKGMTPKIRSNQ-FG-L
RVASRVKTVTIHPAGLPVAIGERLNPTGKKALQAEIKEGKTEITRRDALAQVEAGAEILDVNVGVAGVDQVAAMERAINALQVLVDAPLCIDSTDPEVIE
QALKLYHGKAIINSVNGEEKSLKTILPLAKRYGAALIALTLDDQGIPPTASERLAVARKIVQRAEEMGIPREDIMVDCLVLTVSAQPEGVPETLKAISMV
KQELGLTTSLGVSNVSFGLPNRPLINAAFFAMALAAGLDAAILNPQDQRMMETLRASAVLTGRDVRAEKYI---REQATG-----TAVTASK--SA-PLE
LYQAVLSGDKDNIISYIDQALAQGLNAMELLDKALIPGIEEVGRRYGEGTYFLPQLMMAGETMTKSFERLRPEL--AKNTKRVGTVVLATVKGDVHDIGK
NIVSVMLANHGFEVIDLGKNVDNEEVIKAAREHRADIIGLSALMTTTMVHMPTVIKRVKELGLNCKVMVGGAAVTAQYAKEIGADGYAQDAVEAVRLAKE
LVG
>tr|D8GNB1|D8GNB1_CLOLD Methionine synthase OX=748727 OS=Clostridium ljungdahlii (strain ATCC 55383 / DSM 13528 / PETC). GN= PE=4 SV=1
-MLFKDLLSN-KFVFFDGAMGTMLQRAGLKVGELPETLNITNSEIIRKVHREYLNAGSDIIITNTFGANELKYSSDYTIKDVITAGVKIAKEEAKD--LV
ALDIGPTGQVMEPTGSLSFESAYELFKSQVIIGEKAGADIILIETMSDLYEAKAAILAAKENSSLPIFCTMTFQDGRTLMGTDPKTMVFVLESLGVDALG
VNCSLGPGELQDIVDEILKYSSIPVIVQPNAGLPKY-DGENTIYDITSDEFAENVVIMAKKGVRFFGGCCGTSPEFIKTMVKSLKNIVPLDIKE--KNYT
TVCSARDTVFLN---RIKFIGERINPTGRDIYKKELKEGKVNFIQKEAVKQKEEGAHILGLNVGLPEINEVQTMKEAVKAIQKVVQLPIDIDSPNPKVLE
AGVRVYNGKPIINSVNGRKKCMEEVFPIVKKYGGCVIALTIDENGIPDTAEGRVKIAEKIIKTAENYGIKRKDIIVDCLTLTASAQQKEVLETIKAIKIL
KEQFGVKTTLGVSNISYGLPRRCILNRTFLALALQAGLDLPIINTADKGVKDIISAFEVLTNIDKEGKEYVKKYSGKSEG-----EKAKNSG--E-NDKN
LKQTIIDGMEEEAVELTCKLLKSK-KAVDIVNSYIIPALDEVGVQYENKDIFLPQLIQSAETVKQAFEIIKKDMLKSGNKISRGKIILATVKGDIHDIGK
NIVKVLLENYGFEVIDLGRDVDISEVVDAIIKNNVKLVGLSALMTTTVSNMKKTIDAIRDKGLQCKVVVGGAVLNQNYADMIGADYYAKDARETVKIAEE
LFS
>tr|B2TP83|B2TP83_CLOBB 5-methyltetrahydrofolate--homocysteine methyltransferase OX=508765 OS=Clostridium botulinum (strain Eklund 17B / Type B). GN= PE=4 SV=1
-MGLKEFIKD-NILVFDGAMGTMLQKEGLKLGENPEIFNIEESEKVKKIHEEYIKNGAMIITSNTFGANELKLENGYTVEEIINAAISLAKEATGN-VYI
ALDIGPIGELLEPMGTLSFDRAYEIFKRQIVQGEKSGADLILIETMTDLYEAKAALLAAKENTSLPVFCTMSFDNGRTFTGCTPESMAITLEGIGADAVG
INCSLGPKELLPIVKRIKKATNLPIMTQPNAGLPKL-SFGEAIYDITSDEFEYWVNEFVKEGVSIIGGCCGTTPKFIKRLRVLADNNKRIIRDK--IEFS
AVCTPSNVVKIE---GVKVIGERINPTGKKLFKEALKNNDIDYILKQAIEQIEAGAEILDVNVGLPEINEKEMMKKVVKEIQGIIDAPLQIDSSNIAAIE
TGLRAYNGKPIVNSVNGEDEVLEKILPLVKKYGASVVGLTLDKRGIPATADERFKIAEKIVKKAKEYGIEKHNVFIDCLVLTASAQQAEVKETLKALRRV
KEELGVKTLLGVSNISFGLPCRELINETFLAMAIANGLDLPIMNPNSTGMMAVINSYNVLANIDKRSEKYISIYGNDTSK-----KNIEVIK--S-ENID
LKYIVIKGLKDEAEEATKHILKTM-NELSVVNEILIPALDEVGLKYEKGEIFLPQLIQCAETVKKAFEVIKKRLVINKNSISKGKIVLATVKEDIHDIGK
NIVKVILENYGYQIIDLGKDVSVETVVDVSLKNDIKLVGLSALMTTTLKSMEETIKGLRENGYKGKVFVGGAVLTSEYAKQIGADYYAKDARESVEIAKI
VLN
>tr|F7NIH1|F7NIH1_9FIRM Methionine synthase, putative OX=1009370 OS=Acetonema longum DSM 6540. GN=ALO_09369 PE=4 SV=1
------------IYLFDGAMGTMLQQAGLPAGACPELWNLEYPDQIAAIHRQYVEAGADIIETNTFGGSRIKLSHGLQVAAINRAAVQAARQACGHK--V
AGSVGPTGRFIEPLGDLSFQDAFNAFAEQITALDQAGADMMIIETIIDIQEMRAALLAAKSVCRKPVICQLTFEDGRTFTGTDAHTAAVILSPLGADVIG
ANCSLGPAQLLLVLETLVKATHKPISIQPNAGLPTL-EGDQTHFPMGPEEFSHWIPKLIAAGAHYVGGCCGTTPQHIKAAREAIDATQSPLLPQP-SPYV
ALASRSKTVYIGQQYPTVVIGERINPTGRRKLAAEIKEGSFTTVKKDALGQLQAGARVLDVNMGVPGIDQAAAMKKAVQELSMLVDAPLAIDTTDPQALE
AGLAAFPGRALVNSVSAEPERLEHFLPLAKKYGAAILCLPLAAGGLPATARERVAIAQNIVAAALAAGLSENDLMLDALTLTIATDGEAARQTLATLQLY
RQHFGYPTVMGLSNISYGLPRRDMINAAFCAMSLHAGLDAPILNPYDPLMQDILATSAVLLGHDAHARQFSARY----AY-----TPPPAPH--EIHILG
IKHCVIQGEKEAVAPLIEQAIQEGYQPLTITDEALTVAMNEVGQAFSAGRSFLPHVMLSAETMRSAFQAIKTYL--PAHVRSLGKVVLATVKGDIHDLGK
NIVAALLENNGFTVIDLGKDVPADTIVAACREHQPDIVGLCALMTTTLPQIDHTIRELRAAGSPAHTIVGGAVLTKEYAAQAGADAYAANGVVAVELCKS
MIA
>tr|C6PZA9|C6PZA9_9CLOT Putative methionine synthase OX=536227 OS=Clostridium carboxidivorans P7. GN=CcarbDRAFT_4126, CLCAR_3857 PE=4 SV=1
-MKIDDLVKD-RFIIFDGAMGTMLQKSGLKVGDLPETLNITNPDIIRNIHKQYIDAGADIIIANTFGANELKYSSKYSIEEVITAGVKIAKEAAQD--LV
ALDVSSIGQMMEPTGPLSFEAAYNLFKKQFVIGEKAGADLILIETMSDLYETKAAVLAAKENSDLPVFCTMTFQNGRTLMGTDPKTMVFVLEGLGVDVLG
VNCSLGPKELMPIVEEILKYASIPVMVQPNAGLPRY-DGKNTVYDITADEFVKYVKIMVEKGVRVLGGCCGTNPEFIKKLCEGLKDSKPLKIEE--KNFS
VVCSSTETVFLE---KVTIIGERINPTGKSKYKEELKEKSVNFIQTQAVKQKEEGAHIIELNVGLPEIDEKEIMIKAVKSVQKVVQLPITIDSPNEEVLE
AGARVYNGKPIINSVNGKTEIMKKVFPVVKKYGGCVIGLTIDESGIPDTAEGRFKIAEKIVNTAKEYGIHKKNIIIDCLALTASAQQKEVLETIKAIKLV
KEKLEVKTVLGVSNVSFGLPRREILNRTFLSMALYAGLDLPIMNTGDEGMKEVISSFEVLSNIDREGKNYVEKYGTKLVG-----KKEEENI--S-SIKD
LKQIIVDGIEKDAITSTEVLLKTK-EPLEVVNSYIIPALDYVGEQYEEKEIFLPQLIQSAETVKKSFEVIKKKIVEQGESISKGKIILATVKGDIHDIGK
NIVKVLLENYGFEVIDLGKDVAIEKVVNTVKEHNVKLVGLSALMTTTVVNMKKTIEALRENNLQCKVFVGGAVLNEQYAEMIGADFYAKDARESVRIAEE
IFR
>tr|A6NZH5|A6NZH5_9FIRM Putative 5-methyltetrahydrofolate--homocysteine methyltransferase OX=411467 OS=Pseudoflavonifractor capillosus ATCC 29799. GN= PE=4 SV=1
-M-FLEKLGR-ERLFFDGGTGTLLQAQGLKGGELPETWNLRYPERIQAVHKAYLEAGSHVICTNTFGANALNFPDEWDLDELVRAAVDNAKKARAE-AYI
ALDLGPTGRLLRPMGDLDFEDAVALFARVVRVGAQAGADLVLIETMSDGYEAKAAVLAAKENSDLPVVVTTVYDNGKMLTGGTIASTVALLEGLRVDALG
VNCGMGPEQMLPLAEELVKLASVPVVVNPNAGLPRR-EGDKTVFDVDPERFAAVMERIAKLGVWGLGGCCGTTPDHIRALTAACRNIPVTPPER--KRRT
VVSSFSQAVEIGP--KPVIIGERINPTGKKRFKEALRGHDLEYILNEGFAQEEAGAHILDVNVGLPEIDEPAMLEEAVCALQSVIPLPLQIDTSDTEAMA
RAMRRYNGKPMINSVSGKAESMAAVFPLVRKYGGVVVGLALDEGGIPETAEGRLAVARKIYNTAAEYGIPSEDIVIDGLTLTVSSEPKAAVVTLETLRRV
RDELGGHTILGVSNVSFGLPRRDIINANFFAMALEAGLSCAIINPLAEGMMGAWRSYCALAGLDNQCGGYIGAYSGQTAA---------------PAELS
LEECVTRGMQEGAAQSARTALDKA-QPLELVNSALIPALDKVGQGFEKKTLFLPQLLMSAEAAKAAFEVVKAAMAS--EQEKQGKVVLATVKGDIHDIGK
NIVKVLLENYGFEVIDLGKDVAPEKIVAAAAAPDIQLVGLSALMTTTVVSMEETIKALRESGSGVKVVVGGAVLTQEYADSIDADCYARDAMATVRYAKE
VYG
>tr|E0QLH5|E0QLH5_9FIRM Vitamin B12-dependent methionine synthase OX=864565 OS=Eubacterium yurii subsp. margaretiae ATCC 43715. GN=HMPREF0379_1950 PE=4 SV=1
-I-FRELIGK-KIIYLDGGMGSVLQQKGLQAGELPEILNITNPKLIQEIHYEYYLSGSNVTYSNTFGANKLKYEDEHDYKELIVAAIDNVRAAREREKFI
ALDVGPIGKLLKPVGDLDFEEAVEIFKEVIKTGADAGADLIAIETMSDTYELKAAVLAAKEVCDLPIIATVAFSDKRLLNGADAKTVISLLEGLRVDALG
MNCGLDPRNIKDIVEEFLQYSSLPLVLKPNAGIPEN-INGEIKFNMEPDDFGKIMREFVEMGANIVGGCCGTTHDHIRRLYEETCTLPLIAPTF--KNHT
FVSSYTKTVICNE---PKIIGERINPTGKKLLKQALINKDMSYILKEAIAQEEKGAHILDVNTGLNEIDEQEMSLAVMRAIQEISTLPLQIDSAKTNVLE
TSLRYYNGKAMLNSVNGKKKVMEEIFPIVKKYGAVVVALTIDDDGIPNDAIGRYNIAKNIVETAKTYGIDKKDIVVDPLCMTISSDKNAANQTLKALSMI
KENLGVKTILGVSNISFGLPKRELINHTFFTSALRCGLDFGIINPGSDTMMMAYDAHMVLAGFDENSSNYIAKYSNDT--------ATHVAK--T-SDIS
LKEAIKKGLKEDSFNIAKNMLNDH-QPLDIINSELIPALDEVGAGFEKGVIFLPQLMMSADSASRAFDALKEKMTAMEDSKEKQKIILATVKGDVHDIGK
NIVKVLLENYGYDVYDLGKDVDYDLILDTIEKEKVYLVGLSALMTTTVDNMQETIRLIREKEVEVKIMVGGAVLTKAYAEKIGADRYCKDAMESVRYAKE
VFG
>tr|D4M5L1|D4M5L1_9FIRM B12 binding domain./Pterin binding enzyme./Homocysteine S-methyltransferase OX=657313 OS=Ruminococcus torques L2-14. GN=RTO_19850 PE=4 SV=1
-M-IRERLGK-ELLYFDGGMGTLLQAKGLQPGELPETWNVTHADEIKNIHKQYISAGSDIVLANTFGANALKFHCDFPLEEIIRLAIRHVKDAAEERIYT
ALDVGPTGKLLKPMGDLDFETAYETFKEVMILGEKAGADLIHIETMSDTYELKAAVLAAKENTSLPVFATTIFDRGKLLTGADVPSVVAMLEGLRIDALG
INCGMGPEQMLPILEQIMKYSSVPVIVKPNAGLPKQ-KDGETYYDVSPEEFASVMRHVVDLGAVVIGGCCGTTPAHIAEMVKQCKDIPVKPIEK--KSYT
VVSSYGQSVFLGT--GSKIIGERINPTGKKRFKQALKEHDLDYILKEGIAQQDNGAHILDVNVGLPDIDEPTLMKEVVQELQSVTNLPLQIDTVDTVAME
NALRIYNGKAMVNSVSGKQESMDAVFPLIRKYGGVVIGLALDEDGIPATAEGRVQIAKKIIAEAAKYGIEKKDIVIDALAMTISSEPEGAKVTLETLRRL
RDEVGVCTVLGVSNISFGLPSRPIVNSIFYTMAMQNGLSVGIINPNSEDMMKAWYAYHALMNLDSNCENYINKYAQQPGT------APVSAT--GSAKMT
LKSAIERGLREEANSITSEMIQEK-DGLEIINEELIPALNTVGEGFEKGTVFLPQLLMSAEAAKTAFAVLKEKMDSSGEQEKKGKIILATVKGDIHDIGK
NIVKVLLENYSFDVIDLGKDVPPETIVDTVLEQDIHLVGLSALMTTTVVSMEETIRQLREKAPHCLVMVGGAVLNQDYADMIGADFYGKDAMQSVHYAQR
VFG
>tr|F4XDD6|F4XDD6_9FIRM Vitamin B12-dependent methionine synthase family protein OX=552398 OS=Ruminococcaceae bacterium D16. GN=HMPREF0866_01857 PE=4 SV=1
-VEFLELLT--DRVLLDGGMGTMLQARGLPVGATPELVALEHPDWLRDIHTAYLDAGSQIIYANTFGANREKLERGRTVEEIVTAAVTVAKEAATG-GLV
ALDIGPCGQLLEPTGMLGFEDAVDLFAQVVRAGVKAGADLIAIETMTDLQEARAALLAAKENSNLPVLVTMTYESGRTFLGCSPAAAALTLEGLGADAVG
VNCSLGPREMPPLVEELLKWTNLPIVLKPNAGLPHP-DGS--GYDITPLEFAQSLAALADMGVKVFGGCCGTTPEYIALLSKELTGKTVKAVPR--HVPA
AVCSATQAVPID---RVRVIGERINPTGKKLMKEALRRGDVDYMLGQALAQTEAGADILDVNVGLPEIDEADMMVRTVKALQGVTDAPLQLDSTDPKVLE
QALRVYCGKAIVNSVNGESASLETILPLVKKYGAAVVGLTLDENGIPKNAQARFEVAKRILERAMALGIRREDVYIDCLTLTVSAEQAAASQTLEALHRV
KTELGLKTVLGVSNISFGLPARPLVNQNFLTMAMSAGLDLPIINPNVDAMMAAVRCFHLLTNVDTDAREFIAAYANTSIT-----AGSAPAA--P-QST-
RSLKVIAGLKGEAGQATRALLETT-APMDIVDNVLIPALDQVGADFEQNKVFLPQLIQSAGAAQAAFEVIREKLSTGEGNVSRGNVVLATVKGDIHDIGK
NIVKVLLENYGYTVIDLGRDVDPAAVVEAARKYEAPLVGLSALMTTTLKSMAQTIAQLHDAGLPCKIMVGGAVLTPEYAKEISADFYARDAKESVDIAKR
VVG
>tr|F0Z5M5|F0Z5M5_9CLOT Vitamin B12-dependent methionine synthase family protein OX=556261 OS=Clostridium sp. D5. GN=HMPREF0240_04431 PE=4 SV=1
-M-ILDRLGK-ELLFFDGGMGTLLQAGGLKPGELPETWNMTHPEKITGIHRKYIEAGSDIILTNTFGANALKFHDSCSLCDIVTSAVGHVKRAAEQQVYT
ALDIGPTGKLLKPMGDLEFEEAYEAFREVVRYGAEAGADLIHIETMSDTYELKAAVLAAKENTDLPVFVTTIFDRGKLLTGADVPAVVALLEGLRVDALG
INCGLGPGQMLPILEQILEYTSLPVIVKPNAGLPKQ-VERETVYDVLPQDFAMTMQKIIGQGAAVAGGCCGTTPEHIKSMVDLCRGMEPLPIIQ--KDIT
IVSSYGKSVCLGT--GSKIIGERINPTGKKKFRQALKEHDMDYILREGIMQQDMGAHILDVNVGLPDIDEASMMQDVLVELQSVTSLPLQIDTVDTKAME
AALRIYNGKAMVNSVSGKQESMDAVFPLIQKYGGVVIGLTLDESGIPDTAEGRVEIARHIIEEAAKYGIQKKDIVIDVLAMTISSDPEGAKVTLEALKKV
RYGLGVNTVLGVSNISFGLPSRTVINANFYTMAMQNGLSAGIINPSSEEMMKSYYAYHALMNLDSNCEAYIAKYAGQAAE------SSASPA---VSDMP
LNRAIEKGLKEEAHHITGLLVKEQ-APLDIINTYLIPALDNVGKGFEKGTVFLPQLLMSAEAAKAAFTILKESLAATGQDEKKEKVVLATVKGDIHDIGK
NIVKVLLENYGFDVIDLGKDVAPGLVVEKVLAEDVHLVGLSALMTTTVVSMEETIQQLRQKAPGCRVMVGGAVLNQEYADMIGADFYGKDAMQSVYYAQK
LLQ
>tr|B6FS50|B6FS50_9CLOT Putative uncharacterized protein OX=500632 OS=Clostridium nexile DSM 1787. GN=CLONEX_02974 PE=4 SV=1
-M-LLERLGK-ELLFFDGGMGTLLQAEGLQPGELPETWNIERKETIRKIHQSYFEAGSDIVLTNTFGANALKFHDNCSLKAIIDAAVENVRFGAKADYYV
ALDIGPTGKLLKPLGDLSFEDAYEAFKEVVQYGEKAGADLIHIETMSDTYEVKAAVLAAKENTNLPVFATMIFDKGKLLTGGDVPSVVALLEGLRVDALG
INCGMGPKQMLPILQQIAQYTSLPIIVKPNAGLPKQ-RDGQTYYDVTPDVFAKQLQEIVKAGACVIGGCCGTTPKHIRAMISACKDLEMTKPTF--KNHT
IVSSYGKAVELGD--MPVIIGERINPTGKSKFKQALKEHNLDYILKEGITQQDKGAHILDVNVGLPDIDEVVMMKEVVRELQSVTSLPLQIDTVDTEAME
QAMRIYNGKPMVNSVSGKQESMNAVFPLIQKYGGVVIGLTLDENGIPKTAKGRLEVAGKIIEEAKKYGIDKKDIVIDVLTMTISSEPNGAKTTLEALKMV
RDTYGVRTALGVSNISFGLPSRPVINANFYTMAMQNGLTAGIINPSSEDMMRSYHSYCALMNYDTNCENYIAHYGNQEPA------KTTVPA--G-QQID
LKTAIEKGLKEDAYQTTVALVKTK-EPLEIINTYLIPALDTVGKGFEKGTVFLPQLLMSADAAKSSFAVLKEELEKNGGEKEKEKVILATVKGDIHDIGK
NIVKVLLENYSFEVIDLGKDVAPECIVETVLEKEVKLVGLSALMTTTVVSMEETIRQLREKAPDCKVMVGGAVLNQEYADMIGADFYGKDAMQSVYYAQK
ILT
>tr|E3DMZ0|E3DMZ0_HALPG Methionine synthase (B12-dependent) OX=572479 OS=Halanaerobium praevalens (strain ATCC 33744 / DSM 2228 / GSL). GN= PE=4 SV=1
-MNLKSKLGK-EVIIFDGAMGTVLQKQGLEIGKFPEKLNLEAPRRIIEIHKSYLKAGADIITTNTFGANSLKLKGQYSVEQIISAAVKNAKVAVAE-FAI
ALSLGPLGELIEPNGKLSFKKAYKLYQKQVLLGVENGIDLIQIETISQLAAARAAVLAAKENSDLAIFCTLTFTSGRTFTGCNLRSMISVLEGLGVDALG
LNCSLGPKKAEVLVEKILKYSKLPVILQANAGLPVI-EAGKTNYKISPATYYTPLARLYQQGLAIIGGCCGTTPEYISLIADKLKGKKIKKRKI--IKKD
LVCSAVEYSDLS---GINVVGERINPTGKAEFKENLKKGNLDYLLKIALAEIEAGADILDINLGLPEIDEKKMMLKFIQELQQNITKPLQIDSTNLEVIE
TALRNYNGIAIINSVTGKKDSLEKVLTVAKKYGAFVIGLTIDENGIPETAAGRLKIAEKIVNKAVELKISKDKIIIDCLALTVSAQPKSIEKTLTALKLV
QEKLEVKTILGISNISFGLPARSILNRSFLTMALAQGLNLAIMDPNDPEMMATVKAVSVLKNLDQGAEKYIDFISHQSKT-----IKTKKQK--S-EKKD
LKELIISGLKDETKKLTKELLLEK-EPLEIIDQHLIPALNLVGEKYEKGELFLPKLLKTAATVKESFSVLKMQMKQENQKLAKGKILLATVEGNVHDIGK
NIVKVLLENYNYQVIDLGKNIETEKIVNTVLKNEIKLLGLSALMTTTVKNMQKVIKAVKKAAPNCKIMVGGAVLTADYAKMIKANFYAQDAQTAVEIANN
LFL
>tr|G9XA76|G9XA76_9FIRM Putative uncharacterized protein OX=796940 OS=Eubacteriaceae bacterium CM5. GN=HMPREF9628_00901 PE=4 SV=1
-I-FRDLLRK-ELIILDGAMGSVLQQKGMQAGELPEILNITNPELIQDINEAYYKSGANVTYTNTFGANRLKFEGSYDFKEIIKAAVKNAQIARENEKFV
ALDIGPLGKLLKPIGDLEFEDAVDIFKEMIEAGVEAGADLIAIETMSDTYELKAAVIAAKEVCDLPIIATVAFSDKRLLNGADAKSVIALLEGLRVDVLG
FNCGLDPRNIDDLVEEFISYSSTPIAIKPNAGIPEN-VNGVIKFNLEPDGFGKIVGDFVEKGVMLVGGCCGTTPEHIKKLYEYTKDKKICKQTF--KNHT
LISSYTKCVVCDR---PIIIGERINPTGKKLLKQALMNKDFSYILKEAVIQEENKAEILDLNVGMNDIDEEEMMIKTIRAVQEISTLPLQIDSAKINVIE
QGLRIYNGKAMLNSVNGKKESMEKIFPLVKKYGAVVVALTLDENGIPENAQGRYKIAEKIVKTAKEYGIDKKDIVVDPLCMTISSDKNAANETLKALYLI
KKNLGVKTTLGVSNISFGLPQRELINHTFFSMALKTGLDFGIINPLAEDMIRAYDVHMVLVGLDENALNYISKYSQAK--------ETQTPI--K-NQMT
LCESIKKGLKEDSFMIAKSMLSDK-QPLDIINEELIPALDEVGLGFEKGTVFLPQLMMSADAASRAFDALKEKLISLEDSKEKDKIILATVKGDIHDIGK
NIVKVLLENYGYDVYDLGKDVDYDTILDAIVKENAKLVGLSALMTTTVDNMQKTIELIKEKTPKTQIMVGGAVLTKDYSMKIGADRYCKDAMESVRYAKE
VFG
>tr|B6G243|B6G243_9FIRM Putative uncharacterized protein OX=500633 OS=Clostridium hiranonis DSM 13275. GN=CLOHIR_02205 PE=4 SV=1
-MEIRDYLKTGKVLMFDGAMGTMLQRNGLKMGENPEIFAYKNPDILRDIHRQYLDAGTNTVLTCTFGCNELKLPEGYTVEMIIDNAVKTAREAIEEKKFV
ALDIGPIGEMLEPMGTLSFDRAYEIFKREVVRGVKAGVDVIVIETMMDLLEIKAAVLAAKENSDLPVFATMTFDDGRSFTGCLPESMVYTIGGLGVDAIG
VNCSLGPVQLLPIVEKICSVAQIPVMVQANAGLPSM-HDGQATYDIGPDEYWEGVKKFIEAGASIIGGCCGTDPSYIKKISDNLSNVEIGDKNN--EYVS
AVCSPSKVVRID---EPRVVGERINPTGRKAFKEALKSGNTDYAVRLAIEQVNGGADILEINTGLPGIDERKAMVDILKEVQSVTDTPVQIDSSVVESLE
AGLRYCNGRTIVNSVNGKDESLEAILPLVKKYGACVVGLTLDERGIPEKAEERVEIAKNIIKRAEEFGIRREDIYIDCLSLTVSAQQEAAYETLKAMKEV
K-KLGVHTTLGVSNISFGLPNRQAVNSAFLTLALDAGLDLAIINPNNERMMEAITSYKVIRNIDKGCTKFVERYSDVDNK-----KDVKSSTS-S-SEMS
LFDLVEKGIKDEAKSKTIEMLKDT-DENYILDEILIPALDVVGKKFEKGEIFLPQMIQSAEAVKASLTVIKENLISKNDDVSKGKIILATVEGDIHDIGK
NIVKIMLENYGYEIIDLGRDVPVDKVVEKAVEENIKLVGLSALMTTTVKSMEETIKALKEKMPEVKIFVGGAVLTEDYASEIGADFYAKDAKSAVEIAKI
IL-
>tr|B0A6J2|B0A6J2_9FIRM Putative 5-methyltetrahydrofolate--homocysteine methyltransferase OX=445973 OS=Clostridium bartlettii DSM 16795. GN= PE=4 SV=1
-VEVRQYIQD-NILIFDGAMGTMLQGRGLQAGQNPEAFGFDNPDVLVDIHKEYFKAGANVATTDTFGCNELKLPQGYELEKVIDSAIKSAKKAASLKKYV
ALDIGPIGEMLEPMGTLSFDRAYEIFKRQMVQGEKSGADIIVIETMMDLYEIKAALLAAKENTNLPVFCTMTFDNGRSFTGCLPESMVVTLQGLGADAIG
VNCSLGPDLLIPIVEKIIKRATIPVMVQANAGLPCI-KCGETVYEMTAGQFLEGASKFAKMGAKIIGGCCGTNPEFIKALAENIKDVEVEPLEK--NLEC
VVCSPSKILEIS---GPTIMGERLNPTGRKPLQDALINGDLDYVVSLGLDQIEEGAEILNMNVGLPEIDEKVMMPKVIKTLQEIINVPIQLDSSNVEALE
QGLRYYNGRTIVNSVNGKEEALNKILPIVKKYGAGLVGLTLDENGIPKTAEGRFEIAKKIVERAESYGIRRQDIFIDCLSLTVSAQQEEAMETIKAIRMV
KENLGCKTILGVSNISFGVPNRRALNSTFLNLALGAGLDLAIINTSEEVMMESMYAYRVINNIDKGCEKYIKKYMDAPKS-----SNSKTSNNDS-KEMS
LDILVERGLKDETKELTNKLLEEH-DGHYILDKILIPALDKIGVKYDNGEIFLPQMIQAAETIKVSLNIIKDKLSVNTSNETKGKIIVATVKGDIHDIGK
NIVKIMLENYGYEVIDLGKDVPIETVVETAKKQNIKLIGLSALMTTTVQNMKDTIKAIRESGIDAKVIVGGAVLTEEYAKKIDADYYAKDAKSSVEIAKL
TF-
>tr|A6BDT3|A6BDT3_9FIRM Putative 5-methyltetrahydrofolate--homocysteine methyltransferase OX=411462 OS=Dorea longicatena DSM 13814. GN= PE=4 SV=1
-M-LLERLGK-ELLYFDGGMGTLLQSKGLQPGELPEVWNLEHAEEIIDIHKAYFEAGSDIVLSNTFGANAIKFHDKYGLKEIVTAGIQNAKKAAERKTYV
ALDVGPTGKLLKPMGDLSFEDAYDAFKETMIYGEQAGADLIHIETMSDSYEVKAAVLAAKENTSLPVFATMIFDKGKLLTGGDVPAVVTMLEGLRVDALG
INCGMGPEQMLPILEDILKYASVPIIVKPNAGLPKQ-RDGEVYYDVEPEQFAGYMAKIVEMGAHVIGGCCGTTPAHIQKMVETTREMSVKPATK--KDIT
MVSSYGHAVILGG--KPMIIGERINPTGKKKFKQALKDHDMDYILKEGITQQDKGAHILDVNVGLPDIDEPAMMKEVIMELQSVSSLPLQIDTVDITAME
AAMRIYNGKPMVNSVNGKQENMDAVFPLIKRYGGVVIGLTIDEDGIPATADGRVRVAGKIIEEAKKYGIDKKDIVIDVLAMTISSEPEGAKVTLEALKKV
RETYGVCTVLGVSNISFGLPYRPAVNSNFYTMAMQNGLSAGIINPSSEDMMCSYYSFCALMNYDKNCEDYIRVYGSQKAG------TPAPAA--K-AELT
LKEAIEKGLKEEAHHATGELLKEQ-APLEIINEHLIPALDTVGKGFEKGTVFLPQLLMSADAAKIAFAVIKDVLAQEGGVQAKNKVILATVKGDIHDIGK
NIVKVLLENYSFDVIDLGKDVPPEVIVDTAVEQDIRLVGLSALMTTTVVSMEETIKLLRERKPECKVMVGGAVLNQDYADMIGADFYGKDAMQSVYYAQR
VFG
>tr|I9MAV3|I9MAV3_9FIRM Homocysteine S-methyltransferase OX=1122947 OS=Pelosinus fermentans DSM 17108. GN= PE=4 SV=1
------------IYIFDGAMGTMLQNAGLPPGYCPELWNQEQPAVITAIHKSYIDSGSDIIETNTFGANRIKLTHGLKVALLNTAAVQAARAACGDK--I
AGSVGPTGKLIVPLGDLSFDDAYNVFFEQISALDQAGVDMILIETIIDIQEMRAALLAAKAASKKPVICQMSFGDERTVTGTDPITATIILEAMGADIIG
VNCSLGPAQLLPIVEKIAQTTNCPISVQANAGMPSL-INKQTVFPMQPEEMGLWAKKLVAAGARYVGGCCGTTPQHIKSIYQAVKHLDLPTVQSA-KKST
ALTSRSKTIYLGAGHPTVIIGERINPTGRKQLAADIAAGQFISVKKEALSQVRAGAHLLDVNMGVPGIDQAKAMQYAIQELSMLVDVPLVIDTTDVNALE
AGLKAYPGRALINSVSAEPERLKSFLPLAKKYGAAILCLPISPAGVPKTAQDRLVVIQEIIHKAFETGLKPGDFVLDALILTAAADARAGLEALATLKLY
RQHLGYPTTMGLSNISFGLPRRDIINATFCAMALDAGLDAPILNPYDPLMQQTLAASALLLGDDPSGRSYSVNY----AP-----TSQERAA--PLNIIE
IHLAIVSGEKEAVVPLVEQALREGHKSIDISEQALTTAMNKVGIAFGNGQCFLPQVLLAAESMRAAFLTIKKEL--PAHTTSLGTIILATVKGDIHDLGK
NIVAALLENNGFTVIDLGKDISPEKIVEKALEHKADIVGLCALMTTTMPQIDHTIAALKAAGCSAQTIVGGAVLTQEYANQANADSYAANGVDAVTIAKG
FMA
>tr|F7KQ89|F7KQ89_9FIRM Putative uncharacterized protein OX=658085 OS=Lachnospiraceae bacterium 5_1_57FAA. GN=HMPREF0993_01133 PE=4 SV=1
-M-ILERLGK-ELLYFDGGMGTLLQSKGLKPGELPEVWNIEHADEVVDIHRQYFEAGSDIVLANTFGANALKFHDSYDLKEIVNAAIENVKKGASLRTYT
ALDVGPTGKLLKPMGDLGFEDAYEAFREVMKYGEEAGADLIHIETMSDTYEVKAAVLAAKETTDLPVFATMIFDKGKLLTGGDVPSVVALLEGLRVDALG
INCGMGPEQMLPILEEILAYTSLPVIVKPNAGLPKQ-KDGQVYYDVDPDQFAQTMEKIVHMGACVIGGCCGTTPGHIRAMVERTKGLSVILPSH--KDLT
IVSSYGKAVMLGE--KPVIIGERINPTGKKKFKQALKDHDLDYILKEGITQQDKGAHILDVNVGLPDIDESAMMQEVVTQLQSVTSLPLQIDTVDAKAME
TAMRIYNGKPMVNSVNGKKESMDEVFPLIRKYGGVVIGLTIDEDGIPQTAEGRVKVAGKIIEEAGKYGIDKKDIVIDVLAMTISSEPEGAKVTLDALKGV
REAYGVRTVLGVSNISFGLPYRPAINSNFYTMAMQNGLSAGIINPSSEDMMRSYYSFLALMNYDSNCEAYIRQYGSQPV-------PPAASS--G-SRMT
LKEAIEKGLKEEAHHATRTLLKEQ-EPLSIINQYLIPALDVVGKGFEKGTIFLPQLLMSADAAKIAFAVLKDELAKSGGMEKKDKIILATVKGDIHDIGK
NIVKVLLENYSFDVIDLGKDVPPKTIVETAIKEEVSLVGLSALMTTTVTSMEETIRLLRKHKPDCKVMVGGAVLNQDYADMIGADFYGKDAMQSVYYAQR
VFG
>tr|B5CM24|B5CM24_9FIRM Putative uncharacterized protein OX=471875 OS=Ruminococcus lactaris ATCC 29176. GN=RUMLAC_00498 PE=4 SV=1
-M-LRERLGK-ELLYFDGGMGTLLQERGLQPGELPETWNLLHAEEIREIHRKYIEAGSDIVLTNTFGANALKFHDAYSLEEIVNAAVGHVKAAAEQRIYT
ALDIGPTGKLLKPMGDLDFETAYEAYKEVMIYGEKAGADLIHIETMSDTYELKAAVLAAKENTSLPVFATTIFDRGKLLTGADVPSVVALLEGLRVDAFG
INCGMGPEQMIPILEQITKYSSLPVIVKPNAGLPKQ-KNGQTYYDVSPEEFAEVMKKIVEMGAVVIGGCCGTTPDHIKAMADACRMIPIKPVEK--KNFT
MVSSYGQSVFLGT--GSKIIGERINPTGKKRFKQALKEHDLDYILREGITQQDNGAHILDVNVGLPDIDEPALMKEVVQELQSVTSLPLQIDTVDVEAME
GALRIYNGKAMVNSVSGKQESMDKVFPLIQKYGGVVIGLALDENGIPADAEGRVQVAKKIIAEAAKYGIEKKDIVIDALAMTISSEPEGAKITLETLRRL
RDEVGVCTVLGVSNISFGLPSRPIVNSIFYTMAMQNGLSVGIINPGSEDMMKAWYAFHALMALDSNCEKYIARYAQQPGT------TPVQAA--GGKTMT
LQSAIERGLKEEASSITAELAEQK-DALDIINEELIPALNNVGEGFEKGTVFLPQLLMSAESAKSAFAVLKERMDQSGEQEKKGKVILATVKGDIHDIGK
NIVKVLLENYSFDVIDLGKDVPPEKVVETVLEQDVHLVGLSALMTTTVVSMEETIRQLREKAPDCLVMVGGAVLNQEYADMIGADFYGKDAMQSVHYAQK
VFS
>tr|B1C621|B1C621_9FIRM Putative 5-methyltetrahydrofolate--homocysteine methyltransferase OX=445971 OS=Anaerofustis stercorihominis DSM 17244. GN= PE=4 SV=1
-M-ILKLIKK-RKVFFDGGMGSLLQEKGLKAGEFPEMWNVDKSDVVKDIHKEYLLSGADIISANTFGCNSLKFDKTYSVENIIRSGVRNAKEAVKEDAYV
ALDIGPTGKLLKPLGDLDFNDAYEIYKEIILFGVKENPDIILIETMSDGYEAKAAILAAKENCDLPVFVSMTLGDGKLLTGGNAESIIAMMEGLRVDIIG
LNCGLGPLQLKPFIGKMLEVSSTPLMLNPNAGLPRS-EGGKTVYDINSGEFAFTMKEIADMGVSVLGGCCGTTPEHIKKTVELCKYVEIKEITK--KDLT
MISSFSKCVYIDK--DPIIIGERINPTGKKRFKQALIEDDIEYVLNEANTQVEAGAHVLDVNVGLPEINEAEMMEKVIKELQFSVDVPLQVDTSNTEAME
RALRLYNGKALINSVNGKKEVMDEVFPLVKKYGGVVVALCLDEDGIPSTAKGRIKIANKIIKEAEKYGIERKDIIIDALAMTVSADTSSALVTLDTLSIV
KNELKMNSVLGVSNISFGLPNRMIINSVFFAMALDRGLNAAIINPNNEDMMRSYISFRTLSDMDEKCMDYIDKYASEKRE------TGIKKE--G--LMS
LEDSIVKGMKERAKTATLEELEKS-EPLEIINKKLIPSLDIVGKGFEEGTIFLPQLLMSAEAAKAAFNEVKNHLVKSGQEEKIGKIVIATVKGDIHDIGK
NIVKVLLENYGYDVIDLGKDVDPDLIVNTVIKEDVKLVGLSALMTTTVPSMEETIKKLNKKVPDCKVFVGGAVLTKDYAKTINADYYAKDAMASVAYAEN
LFK
>tr|C0C3T5|C0C3T5_9CLOT Putative uncharacterized protein OX=553973 OS=Clostridium hylemonae DSM 15053. GN=CLOHYLEM_06747 PE=4 SV=1
-M-ISQRLGR-ELLFFDGGMGTLLQSKGLKPGELPETWNLTHREEIIDIHRQYVEAGSDIVLTNTFGANALKFHDEYDLEEIVTSAVGNVREAARTRVYT
ALDIGPTGKLLKPMGDLGFEEAYEAFKEVVRYGEAAGADLVHIETMSDTYEVKAAVLAVKENTDLPVFATMIFDRGKLLTGADVLSVVALLEGLRVDALG
INCGMGPEQMMSILDEIMRYTSIPVVVKPNAGLPKQ-REGEVYYDVDPEHFAEAMCRIVKKGACVIGGCCGTTPAHIKAMTERCAGLVPAVPTS--KKET
VVSSYGQGVVLGD--RPVIIGERINPTGKSKFKQALKEHDLDYILREGITQQEKGAHILDVNVGLPDIDEVSMMREVVCELQSVTSLPLQIDTVDIEAME
AAMRIYNGKPMVNSVNGKKESMDAVFPLIQKYGGVVIGLTIDENGIPDSADGRVKVAGNIIEEAAKYGIDRKDIVIDVLAMTISSEPEGAKVTLEALRKV
RECYGVRTVLGVSNISFGLPFRPAVNANFYTMAMQSGLSAGIINPSSEDMMRSYYSFCALMNFDHNCEQYIAQYGSQ---------TSAPVQ--M-SEMT
LKSAIEKGLKEESYQAALRLVKEK-APLEIINEYLIPALDVVGKGFEKGTVFLPQLLMSADAAKLAFAVLKEELARSGEAQKKEKVILATVKGDIHDIGK
NIVKVLLENYSFDVIDLGKDVPPEEIVLRAVSEDVRLVGLSALMTTTVVSMERTIKLLRRDKPDCKVMVGGAVLNEEYAEMIGADFYGKDAMQSVYYAQK
ILQ
>tr|I0GUT3|I0GUT3_SELRL Putative 5-methyltetrahydrofolate-homocysteine methyltransferase OX=927704 OS=TAM6421). GN= PE=4 SV=1
------------IEIFDGAMGTMLQAGGLQPGACPELMNVENPEVVKNIHRAYIEAGATIIETNTFGASPLKLEHGLRMAELNKAAVTIAKEAAQRK--V
AGSMGPTGRFIEPLGDLSFDDAYTNFFDQATALAEAGADFLIIETCIDLQEMRAALLAAKAACDIPVICQLSYSDGRTVTGTDPQSAAILLDAMGADIIG
VNCSLGPEELVPIVKTLAENCTCPISVLPNAGMPYL-KDGQTVFPMGPEDFGKWGVKLLEAGASYLGGCCGTTPEHIRELANAVKDLPLPERRLP-AKRL
WLTSRSKAVCIDRSLPTRLIGERINPTGRKKLAAEIKEGSLLGVKKEAVNQVKAGAHLLDVNMGVGGIDQAAAMKRAVTEISQLTDAPLSIDTSDAKALE
AGLKAYPGRALINSVSYEPERIAEFLPLAKKYGAAILCLPITPDGVPKTAEERIAVMHKIIAAAKEQGLDDGDFLLDALVMTVSADKNACYEVLITLQMY
RERFGYPTTMGLSNISFGLPNRPLINSTFFAMCLAAGLDAPIMNPYDEAMQRALMASAALLGDDPNGLAYSKNE----AN-----LAVKAAA--KVSPLE
IKQAVIDGEKDEIPSLVENALKSGLEANTITEQALTAAMTDIGVDFGAGRMFLPQVLLSAETMRSAFNKLKELT--PANAANQGTVVIATVKGDVHDLGK
NITGALLANSGFKLIDLGKDVDSTEIVKAAIENNADIVGLCALMTTTMVQIDKVIADLKEAGCDAKVMVGGAAVTQDYADSAGADAYAPDGVKAVELAKE
LVK
>tr|H6LG76|H6LG76_ACEWD Methionine synthase MetH OX=931626 OS=1655). GN= PE=4 SV=1
-MNIKELLKK-KRLYLDGAMGSLLQDKLDEIGPVPEVLNLTQPELIKEIHQQYINAGANIILANTFGVNGYKLKNTYSVDQLVTAGVKNAKSLK---DYV
ALDVGPLGTLIGALGEVSFEQALDYFKEVVEAGDEAGADLIVIETMTDICEARAALIAAKEVSDLPVIVSMTYENKRTLTGSDALTVVNILEALGADAIG
INCSTGPDGMVPIIEDLIEYASVPIMVEPNAGLPQM-VDGKTVYNISIDEFTQYMVQIAEMGALILGGCCGTTPSYIKKMIAATKDLPLYAVNE--KWYT
AVSSSTKTIILGD--DIHIIGECINPTTNPILKASLRQGDLTVVSQLAVEQKKDGAHVLDINLGLPDIDELKMMTEAVDTVSRLVDCPLQIDSSNPEVIE
AVLRGYPGKAIINSVNGKKSAMAKIFPIAQKYGALVLGLTMDETGIPSLAEDRFAIAKKIMAVGESYGISQKNILIDALVLTASAQQAEVRETLKTLAQL
REALGVPTVLGVSNISFGLPNRELLNRTFLGMALEAGLTTPIMNPGDKEMMDTINAFRALWGLDGQCIAYANRYKESSFG-----ESK-SAA--D-KKL-
LKEIIEEGLSDQAAAATRLLLETR-EPLDIVNNEIVPALDAVGDAFETGECFLPHLIFAAETAQKAFEVIKETMQQTGAQVAKGTIILATVEGDVHDIGK
NILKVILENYGYAILDLGKDVKAETIIQSIKAEQIQLVGLSALMTTTVKNMEKIIKEIKTNCPQTTIMVGGAVLNPEYAETIGADYYGKDAREGAGIAQK
VFQ
>tr|F4LV47|F4LV47_TEPAE Methionine synthase OX=499229 OS=Tepidanaerobacter acetatoxydans (strain DSM 21804 / JCM 16047 / Re1). GN= PE=4 SV=1
-MS-KRIDFS-NFIVFDGAMGTMLQTHGLKAGELPESYNILHPEIIEKIHGEYLDAGADVITTNTFGANRIKLSKGYDIGEIVKSGVKIAKAA---KRLV
ALDIGPIGQLMKPYGTLSFSEAYELFREQVIAGADAGADLILIETMSDIYEMKAAILAAKENCNLPVVATMTFQDKRTLTGTDPLTMVNVICGLGVNALG
INCSLGPKEILPLIEEVLSCSKIPVIAQPNAGMPKI-IDGKTVFNVEPDEFARYAKIMAEKGVTILGGCCGTNPEHIRALRHVLAGLEPIKRKV--EPIT
AASSFSKTVIIG---EITVIGEKLNPTGRKHLKEALKSNDMEYVLRQALAQQDAGAHILNVNAGLPEIDEKAVMINIIRELQSTVSVPLQIDSTDSDVIE
AAVRIYNGRPIINSVNGKLKVMEEIFPIAKKYGACVVGLTLDENGIPSKAKDRFKIAENIVKTASKYGIAKEDLIIDCLVIAASAQQDEVREIIKATRLV
KERLGVKTILGVSNISFGLPNRTLLNRTFLALALEAGLDAPIIDPADEEVMGTINAFNVLWGYDKYANNYIAAYAPKDKK-----PAVKAFSA-T-DVAD
IEDIIINGLKEEAAPKVRAMLKAM-SPTQIIDEHLVPSLDIVGRKYEAGEIFLPQLIQSAETAKRAFEAIKHHIIETNKEFSKGKIILATVRGDIHDIGK
NIVKILLENYGFEVIDLGKDVPEDEIIQRIKQDNVSLVGLSALMTTTAQNMANTIKAIRKAGLGCKIMVGGAVVNAEFAKSIGADYYGRDAQESVRIAQE
FF-
>tr|F2JGX5|F2JGX5_CELLD Methionine synthase OX=642492 OS=11756 / RHM5) (Clostridium lentocellum). GN= PE=4 SV=1
-MV-CNVLGK-RRLYFDGAMGTAVQSRGLKLGEVPELFNITHPEIIEEIHRAYLEAGSNFVTTNTFGANRYKIEEGYTVEQIISKAVEIAKAA---ESYI
ALDIGPSGKVLRPVGDVEFEEVYEIFKEQVIAGEKAGCDVILCETFTDLYELKAAVLAAKENTSLPVFCTMSFENGRTFFGTSIESMILTLEGLGVSALG
VNCSLGPKQLKEIVKRITKLSHIPVMVQPNAGLPVM-QGENVHYDITAEEFAEIMKEFAEDGVSILGGCCGTTPEYIEKTVDKTKDIPYELLER--EKVT
GICSSSEVVYFD---DVVVIGERLNPTGKKMLQQALRNHDMDYVLREAIKQQEQGAHILDVNMGLPDIDEVEMLKQAVVEVQSIVGLPLQIDSSNVDALE
AAVRIYNGKPLINSVNGKKESLEAVLPIAKRYGACILGLTLDEKGIPETAEERLIVAKRIVDAAVREGIPKEDIFIDCLVVTASAQQSLVKETLKAVRLV
KEELGVKTILGVSNVSFGLPQRPIINKTMLAMALIEGLDAPIMNPGDAGMMEAISAYRVLMGKDQDSKAYIDKYS--GEN-----SSIGAAM--S-NVIH
NETIIKKGLKEEAKTVTLELMKEK-SPLEMIELDIIPALNEVGKLYETGVIFLPQLIKSAEAAKAAFEILQVEMSKQNERTTKTKVVLATVYGDIHDIGK
NIVKVIMENYNFEVIDLGKDVPSERVIEAVKKHEVRIVGLSALMTTTVNSMKDTITLLRKECEEVKVIVGGAVLTPELAQYVGADYFAKDAMETVRIASS
L--
>tr|E4RIR2|E4RIR2_HALSL Homocysteine S-methyltransferase OX=656519 OS=Halanaerobium sp. (strain sapolanicus). GN= PE=4 SV=1
-MELENRLGK-KVMLFDGAMGTVLQQRGLKAGSVPEILNIGKKEVIIDIHKSYLKAGSEIITTNTFGANKLKMSEDYTVEEIISAAVENAKVIESS-ALV
ALGLGPLGELLEPMGSLTFDEAYSLYQQQILQGVKSGVDIIHIETIADLCEAKAAVLAAKENSNLPVFCTLTFEDGRTFTGGNIHSTISVLEGLGVDALG
LNCSLGPEKLESLAEEVLKYSNTPVILQANAGLPVV-EEGKTVFKLSPEEYYKPIARLYEKGLAVVGGCCGTNEDFIALIADFLKDKAVKKSNN--EEIS
IACTPSKWKDLK---KINVVGERINPTGKNEFKKALRNKDLDYITRVAIEQVEAGADILDVNLGLPEINEEEMMVKVIKELQAILDIPLQIDSSDENVIA
KALRYYNGTAVVNSINGETEVLEKTLPLIKKYGAAVIALTMDEDGIPETAEGRFEIAKRIVNKAEEYGIKREKIIVDCLTLTASAQQKGVKETLKALKMV
KEKLNVNTTLGVSNVSFGLPARAVLNRNFLTLALYQGLNLAIIDPNDSEMMANIKAFKVLANLDKGAVEYIEFMANDQEE-----IKKENSA--I-ETME
LEEIIVKGIKKEAAKLTKKLLAEK-DALEIVNNHLIPALDIVGERYEEGKIFLPQLVQSAETVKEAFAVLKAEMAKNGEDISRGEIVLATVKGDVHDIGK
NIVKTVLENYGYKIIDLGRNVSENEVKKVVKDNNIKLLGLSALMTTTVKNMEKTIQIVKEENPDCLIMVGGAVLTPDYAEMINADYYAKDAKDAVEIAKK
IFG
>tr|B2A781|B2A781_NATTJ Homocysteine S-methyltransferase OX=457570 OS=JW/NM-WN-LF). GN= PE=4 SV=1
-MQLVNKTLE-KLLFLDGSYGTELQRRGFEGN--AEILNLQDQDLVKNVHYDYASAGADLILTNTFGGNRLKLKDGYKVAEINSRGVELAKESAENRVLV
VGDISSTGRFIEPVGDLSFTKAQQVFQEQGRYLIESGVDLIKIETMTDIKELKAAILGIRSIEDLPLIVSMSFEDGKTITGTSVPSYVTLMNDLPVDIIG
LNCGVKSKDMLDLVKQASYYSLKPLSISPNAGDPDL-D---LSYSEDPQEFSFYLDAISDLDVAIVGGCCGTTPEYVDNYCSKLKGKEKSRLLQI-HK-T
LISSRTYQLDLDN-N-FVKIGERINPASKKNFQEEINNKDFSRIYDEAFSQMNEGSDVIDLNLGVEEDVELEDVETIVNGLDSLGCKPLSLDIQSSVLLE
KALQVYPGRPIINSSSCDKEDLDNAIDLMKKYGGVLVLLAMSGT-PKKTIQKRLDELKYGLEYLESKGIDESRIMVDPLVLPVGTEHD-PKTTLELIKII
SQEMECKTTLGLSNLSHGLPDRPQLNSAFVSMAIYNGLDSAIMDTSDQLVTQTVEKSLMLMGKETIWEDVA------I----------D-------DQM-
VKD-ILTGNSDKVLTQVKSYLKDM-TPLEVSQQLLGKAMKEIGDLYNDKSIYLPQLLLSAETVQPSFDYLNKLV--GEHQEDSGKIMLATVEGDVHDIGK
KIVGTILKSGGFEIYDLGVDLPANEIVAEVKDIKPDILGLSAMMTSTIKKIAEVTEQLQAEGIDVKVIGGGASLNPELAQKFGCHAYAKDAHEALTKCEQ
LME
>tr|I7LSB0|I7LSB0_9LACT 5-methyltetrahydrofolate--homocysteinemethyltrans ferase OX=1215915 OS=Lactococcus raffinolactis 4877. GN= PE=4 SV=1
-MTILTDLKT-QILLFDGAMGTQLQDIGLPIGGIPEHFNLTHPEVVEAIHRDYVAAGSDVITANTFQANTTKMAA--ELDETIHTAIALAKKAE---KYV
AYDMGPTGQLLQPMGTLSFDAAYEMFASQAIIAEQAGADLVIIETVADLLEAKIAVLAVKENTKLPVFVTMTYQDGRTFVGVDPQTATLTLQNLGVDVLG
VNCSLGPKELAPIVAKILDYAQIPVMVQANAGLPQM-ENGETVYKITPETYVAYTQKLLAQGVAVVGGCCGTTPEFIRQLIDQTEKVPEPKSG------T
FITSGLKTLEIGL--GLSLIGERINPTGKPRLKEALRENNISYIIQEAVAQRDAGADILDVNVGLPEIDEAKMMVKTIVELQSLLDLPLQIDSSETAALE
AGARHYNGIPLINSVNGKPSSMAKIFPIVAKYGGVILGLCLDDEGIPETAEKRYQIAEKIVHEAGKYGITPDRVMIDPLVLTASAQKEQVPVTLDTIRLV
KERLGCKTVVGLSNISFGLPNRALLNGTFLAQAFGAGLDAPIMNPLSDYMMRVVRSLKVFTGQDTNSEDYIANEQNANAS-----GNQ-AST--D-DTL-
LKGMIIKGRKELTAAETRKMLETM-TPLDIVNTYFIPALDIVGAQFEKGELFLPQLMQSAEATQQAQEVLKAALAKSGKSESLGRLLLATVEGDIHDIGK
NIVKMILENYGYEVVDLGKDVPIETVVETVVTQKIKLVGLSALMTTTVQNMKKTITAIKTVAPDTVFMVGGAVLNEEYREFVGADYYAKDAMASVDITQK
FFK
>tr|C3RK90|C3RK90_9FIRM Homocysteine S-methyltransferase OX=556270 OS=Coprobacillus sp. D7. GN=MBAG_01159 PE=4 SV=1
-VMLQERLKN-DILVFDGAMGTQLQDAGLKAGDIPECLNITDPKLIQTIHLNYLNAGADFITTNTFGANPLKMAEPYSYEEIINAAIDNATIARKTNSYI
VLDIGPIGQLLEPMGTLTFDEAYEIIKKQVII-AKDKVDAVLLETMTDIYEVKAGILAVKENSDLPVFVTMTYENLRTLSGCDPLTMVNVLEGLNVDVLG
VNCSLGPIELTPIIDQILAAATIPVLLQPNAGLPCL-VEGKTCYNMDKETFVQESLKHVKNGVAIIGGCCGTTPDFIASLKNNL-PVRKKIT-P--KRAT
RVSSGTKTVEFG---HVVVCGERLNPTGKKKLKLALKEERYDELVVEAIKQDQAGAHVLDVNVGLPGINEVATMKHVIKLLQEVISLPLQIDSSVPGAIE
QACRYYNGKPLINSVNGKDETMDAIFPIVKKYGGVVIGLTLDENGIPPLAKDRYKIAKKIINKAASYGITKENIIIDCLVLTVSAQQKEVMETVKAVAMV
K-ELGVHTVLGVSNVSFGLPNRPLLNKTFLAMAMSAGLDLPIINPMDQELMATIDAFNVLYNYDHDAAVYIERRANQETI-----TKKDTST------FT
LNDIVLHGLKDEVTNATKELLKTT-PGLEIINNILIPALDTVGKQYEKNIIFLPQLIQSAETSKIAFGIIKDTFK-DT-AATKGPIIMATVHGDIHDIGK
NIVKVVLESYGYKVIDLGKDVPPETVVEAFHKHHPKAIGLSALMTTTVVSMAKTIELLKQIDNICPIFVGGAVLTADYAKEINADYYSKDAMEAVELLNK
II-
>tr|K0B2Y5|K0B2Y5_CLOA9 Vitamin B12-dependent methionine synthase MetH OX=1128398 OS=Clostridium acidurici (strain ATCC 7906 / DSM 604 / KCTC 5404 / 9a). GN= PE=4 SV=1
-MAIKELSEG-KFLLFDGAMGTMLQKAGLKTGELPETYNITNPEIIRGIHEEYVKAGSDVVTTNTFQANELKLKEPYSVEEIIEAGVKIAKDS---AKYV
ALDIGPLGQLMEPMGTVSFERAYEIFKRQIVVGAKAGADIILIETISDIYEAKAAVLAAKENCDLPVFCTLTYQDGRTFVGTDPVTGTIVLDGLGIDAMG
VNCSLGPKELKPIVDKVLEYSKAPVMIQPNAGLPKI-RDGETIYDVTPQEFSEYLIEIAKNGALVLGGCCGTDPSFIKEVRSQLDKLTPVKTNP--KVVT
AATSGSKTVILD---DTTVIGEKINPTGKKKLKEALRTNNLDYIIGEAIDQTNSGADMLDINVGLPEIDEAEMIKKVIREVQGVVNLPLQVDSSDVGAIE
AGVRIYNGKPMINSVNGKKESMEAIFPIVKKYGALILGLALDESGIPETAEGRLEIARKIVNTAAEYGIPKEDVLIDCLVLTASAQQSQVKETLKAIRLV
KRELGVKTVLGVSNVSFGLPNRELINSNFLAAAFGAGLDAPIINPMSKSIMDTVNVFRVINNQDKDSAYYIEHYS--NVE-----PSQAKEISNN-GERD
LRAIIIEGRKEESAPKTREMLDGM-AALDVVNNHFIPALDIVGDRFEKGQIFLPQLIQSAEAVKSAFVVIKDQLKS--EKESKGKIVVATVLGDIHDIGK
NIVSMLLENYGFDVFDLGKDVPIEEVVRVVKEEDIKLVGLSALMTTTVSSMGETIKALRQEGLDCQVMVGGAVLNEEYTDMVGADFFAKDARESVKIANR
VF-
>tr|E6U6U9|E6U6U9_ETHHY Homocysteine S-methyltransferase OX=663278 OS=/ YUAN-3). GN= PE=4 SV=1
-M-VLEDLGK-RIVFFDGGMGTLLQAKGLEPGELPELWNLTHADVVRDIHSAYRAAGAEIIKTNTFGANRFKYPELL--ERVITEGVRLAKEA---DGLV
AMDIGPTGKLLEPIGDLPFERAVEVFGEEAEIGAKAGADLILIETMTDTYECKAAVLAAKERTNLPVFATLVSDKGKLLTGGDIPSAVALLEGLGVNALG
LNCGFGPDLMRRLLPGLLECASVPVIINPNAGLPKT-ERGRTIYTIGPDAFAGEMREIVRGGAWIVGGCCGTTPEYIAAEVRTCKNIVPVPLVP--KRHT
VVSSYAKAVDFAH-IAPVLIGERINPTGKPRLKQALRDGDIDYVLQEGIAQMQLGAHVLDVNVGLPELDEPNVMAKVVSALQGVVDIPLQIDTSSPEAME
RALRLYSGKALINSVNGKEESMHAIFPLVKKYGGVVVALTLDESGIPATAEGRVQIARKIMETAATYGIAPENLLVDPLVMTISAGQENAAVTLEALERI
HRELGLHTSLGVSNVAFGLPEREKLNAAFFTMALQRGLDAAIVNPKSQAMMDVYRAYRALSGKDEQCMEYIAAYSGQKE-------KTAPLS--H-GEIS
LFDAIVTGLKTSAAEAAEQLVVTK-QPLDIIEEQLIPALDQVGYDFETGVLFLPQLLMSAEAARAAFEVLRGKLDVDGQKTRKAKVILATVKGDIHDIGK
NIVKILLQNYSYEVIDLGKNVLPADVVKTARNEQVHLVGLSALMTTTVENMEETIRQLRKDVPACKIMVGGAVLNAEYAARIGADFYAKDAMGAVRYAEQ
LFE
>tr|D5VZD4|D5VZD4_CLOB2 Putative 5-methyltetrahydrofolate--homocysteine methyltransferase OX=758678 OS=Clostridium botulinum (strain 230613 / Type F). GN= PE=4 SV=1
-MNIKDYIKE-NVLIFDGAMGTMLQKLGLKISDLPEELNILEPEKIINIHRKYIEAGAKVITTNTFGANEIKLKQKFSLETIIDKAIDNVKKAGKN-ILI
ALDIGPIGQLLEPMGTLRFEEAYEIFKRQIVQGQKSGADIVLIETMTDLYEAKAAILAAKENTNLPVFCTMTFENKRTFTGCTPLSMVLTLEGLGVDALG
VNCSLGPNELGDIVDEIIKYSSIPIMVQPNAGLPTI-KAGRTIYNIKPKEFADFQRSIVEKGVRIVGGCCGTTDEFIREIVYSLKDAKIKKLKE--KNIC
GVCSSTKSVLIE---GVKIIGERINPTGKKLFKEALRNNDTDYILKEAISQVECGADILDVNVGLPEINEEETMKKVIKEIQSIIDTPLQIDSNNSKVIE
KALRIYNGKAIVNSVNGEEEVLDSVLPLIKKYGAAVVGLTLDDKGIPKKAEERLKVAEKIVNKALEYGIRREDVFIDCLVLTASAQQEDVTETLKAVNLV
KEKLNVKTILGVSNISFGLPNRELINKTFLAMSLQSGLDLPILNPNNKEMINIINAYKVLNNEDKGAANYIERYTNEISN-----SREVKIK--K-NDLT
LKEIVIKGIKEESYSKTKDLLKYR-GELSIINEELIPALDEVGDKYEKGIIFLPQLIQSAETVKKAFTAIKEKLREDNPKISKGKILMATVKGDIHDIGK
NIVKVILENYGFDIIDLGKDVESEKVVEEVKKNNIKLVGLSALMTTTVNSMRDTIKILKESGMDCKVFVGGAVLNEEYAKMINADYYAKDAKEAVDIAKG
FFG
>tr|A8MFL1|A8MFL1_ALKOO Homocysteine S-methyltransferase OX=350688 OS=(strain OhILAs)). GN= PE=4 SV=1
-MKIVNRLKD-GTLIFDGAMGTMLQNRGLKLGELPEMLNFSAPEIVIEIHKSYVDAGADVVTTNTFGANELKLAGPYTVEEVIHKAVVNARTACEG-TYV
ALDIGPIGELLAPMGTLSFQEAYEIFKRQVVQGVKSGADLILIETMTDLYEAKAAVLAAKENANVPVFCTMSFENGRTFTGCTPEAMVLVLEGLGVNALG
VNCSLGPKELGPIVDHILKIATVPVMVQANAGLPTV-VEGRTVFNVLPEDFARHGCNFVEKGVKIVGGCCGTTDRYIEGLKEVLKDRQPGKIEA--ATLT
GVCTPTKVVEIQ---GVRVIGERINPTGKKLLKEALRSGNLDYILREAIAQVDAGAHILDVNVGLPEINEEEIMEKIVQEIQSILDVPLQIDSTNPKAIE
KGLRIYNGKAIVNSVNGEDKVLERILPIVKKYGAAVVGLTLDERGIPKTAEARFEIAEKIVDRALSYGIKREDVYIDCLTLTAAAQQEEVQETLKTIQLV
KKHLNVKTVLGVSNVSFGLPNRDLLNRTFLAASIFAGLDLPIINPLDQGMMETIVASQVLWNQDKSAEAYLKYHQNKTEV-----GSKPKMA--Q-SQED
LFNMIIKGIRDEAKIATENLLQEK-APLDIVNQYIVPALDFVGERYEKGDLFLPQLIQSAETVKSAFEVIKKKLKENASDISNGKILLATVKGDIHDIGK
NIVKVLLENYNYEIIDLGRDVPKEKIVEEVVKNKIKLVGLSALMTTTVKNMEETIEALKKMDPECIVMVGGAVLNPEYAEMIKADYYAKDAKDAVAIAKN
ILG
>tr|G9EY58|G9EY58_CLOSG Putative 5-methyltetrahydrofolate--homocysteine methyltransferase OX=1075091 OS=Clostridium sporogenes PA 3679. GN=IYC_05934 PE=4 SV=1
-MNIKDYIKE-NIIVFDGAMGTMLQKLGLKISDLPEELNVLESEKIINIHRKYVDAGAKVITTNTFGANEIKLKQEFSVERIIDKAIDNVKKARGN-IFI
ALDIGPIGQLLEPMGTLKFEEAYEIFKGQVIQGEKSGADIILIETMTDLYEAKAAILAAKENTNLPVFCTMTFENKRTFTGCTPVSMVITLEGLGVDALG
VNCSLGPNELEDIVDEIIKYSSVPIMVQPNAGLPTV-KDGKTIYNIKPKEFAAFQRSIVEKGVRIVGGCCGTTDEFIREIVYSLKDVQVKKLKE--KNIC
GVCSSTKAVLID---GVKIIGERINPTGKKLFKEALRNNDIDYILKEAIGQVESGADILDVNVGLPEIDEEETMKKVIKEIQSIIDAPLQIDSNNPKVIE
KALRVYNGKAIVNSVNGEDKVLDNLLPLIKKYGAAVVALTLDDKGIPKKAEERLKIAEKIVNKALDYGMKREDVFIDCLVLTASAQQEDVRETLKAVTLV
KEKLKVKTILGVSNISFGLPNRELINKTFLAMSLQSGLDLPILNPNNKEMINIINAFKVLNNQDIGAANYIEMYANETSN-----SKEVKTQ--K-SNLN
LKEIVIKGIKEEAYSKTKELLKDR-AELSIINEELIPALDEVGEKYEKGIIFLPQLIQSAETVKKAFAAIKEKLREDNPKINKGKILMATVKGDIHDIGK
NIVKVILENYGFDIIDLGKDVEVERIVEEVKKNNIKLVGLSALMTTTVNSMKDTIKALKDSGIDCKTFVGGAVLNEEYAEMINADFYAKDAKEAVDIAKR
FFG
>tr|F3B9Y0|F3B9Y0_9FIRM Putative uncharacterized protein OX=742723 OS=Lachnospiraceae bacterium 2_1_46FAA. GN=HMPREF9477_00750 PE=4 SV=1
-M-ILEQLGK-KLLFLDGGMGTLLQAEGLLPGELPETWNAKRRETVINIHRQYFEAGSDIVLTNTFGANAIKFHDFYSLENIIKQAVANVHEGAKKEYCV
ALDIGPTGKLMEPMGDLSFEDAYNTFAEVMQYGKEAGADLIHIETMSDTYELKAAVLAAKENTNLPVFATMIFNNGKLLTGGDVPSAVSMLEGLRVDAIG
LNCGMGPKQMLPILKEMRKYTSLPIIVKANAGLPKQ-KNGETYYDVNPEEFANAMAEIVEEGGCVIGGCCGTTPEHISEMKKMCGNKQIKVPQK--RSET
IVSSYGKAVVFGE--KPIIIGERINPTGKSKMKQALKENQLEYLLKEAITQQEKGADILDVNVGLPDINEPEMMKKVIPEIQSVTNLPLQIDTVNVAALE
GAMRLYNGKPMVNSVTGKQESMDKVFPLIQKYGGVVVGLTLDEAGIPKTAEGRLEIAKKIIREAEKYGIDKKDIVIDVLTMTISSEPEGAKTTLEALEMV
RTICGVHTVLGVSNISFGLPTRPIINANFYTMAMQKGLSAGIINPSSEEMMNSYYAFCALMNLDENCENYIANCMPKTV-------ETKPVT-----TLT
LKMAIEKGLKEETVQSVKSLIQTE-KPLEIINNYLIPALDTVGKGFEKGTVFLPQLLMSAESAKEAFAILKEELSKSGQDAKKEKVILATVKGDIHDIGK
NIVKVLLENYAFDVVDLGKDVPPEKVVEAAKENNVKLVGLSALMTTTVVSMEETIKQLRKEVPDCKVMVGGAVLNQEYADMIGADFYGKDAMQSVHYARK
ILK
>tr|Q893L2|Q893L2_CLOTE 5-methyltetrahydrofolate--homocysteine methyltransferase OX=212717 OS=Clostridium tetani (strain Massachusetts / E88). GN= PE=4 SV=1
-MELKDILGK-EILIFDGAMGTMLQKYGLAVGEIPEILNIKEREKIIEIHKKYIEAGANIITINTFGANDKKLLNGYSVEDIIEAAVENAKIASKE-IAI
ALDIGPIGELIEPMGTLSFEEAYNIFQKQVLQGVKRGVDLILIETMSDLYETKAAILAAKENSNLPIFCTMTFEDGRTFTGCSIPSMVTVLQGLGVDALG
VNCSLGPLELESIVKEMLKYSQIPVMVQPNAGLPKV-IDGKTLYKITPEEFLQAQKRMVDNGVAIVGGCCGTDNNFIKLIAKEFKGKKVINKKV--EKNT
MICTPSKAVIVD---EIKIVGERINPTGKKFLKESLKNKNMNYVLKEAINQVEEGADILDINVGLPDIDEGKIMVKVIKEIQSVLDIPLQIDSNDPEVIE
KALRAYNGKAIVNSVNGEEENLNKILPIIKKYGASIIGLTFDEKGIPLRAEERFHVAKKIVDKAMEYGIKREDIIIDCLTLTTSAQQKEVLETLKALTLV
KKNLGVKTTLGVSNISFGLPNRELLNRTFLNMALFAGLDLPIINTKNREMVDTIKAFKVLSNIDIGGEKFIKEYGGKKN-------KEKVDI--V-KDEE
LKEIIIKGLRERAVYATKELLKKK-TEIQIVEEDLVPALDIVGDRYEKGEVFLPQLIQSAETVQKAFEILKETLTLKDKNISKGKIVLATVKGDVHDIGK
NIVKTLLENYGYTVIDLGKDVSKEKIAEEVKKNEVKLVGLSALMTTTVKSMEETIEMLKNEGLDCKIMVGGAVLNEEYANMIKADYYAKDAKDAIKIARK
VI-
>tr|E3GG57|E3GG57_EUBLK Homocysteine S-methyltransferase OX=903814 OS=Eubacterium limosum (strain KIST612). GN= PE=4 SV=1
-MKFTEALKT-KRLYLDGAMGSLLQAKLENIGPVPEALTLTHPEIIQDIHRAYIEAGADIITTCTFGANGYKLNDEYDQGAIITAAVKLAKELK---GYV
ALDIGPLGALIGSLGEISFDEAYHYFAQMVEIGAAAGADVLLIETVTDIYEMKAAVLAAKEHSNLPVIASMTFENGRTLTGSDPQTVVTVLEALGVDAIG
INCSTGPDKMMPVIDTLLKYASVPVVVQPNAGLPRV-VDEKTFYDITSDEFAAYMAEIAQNGASVLGGCCGTTPEYIQKTIDATKVSPLPDLGE--KQQT
LVATGTRTVALGQ--DIRIIGECINPTTNVALKEELRRGELSLVKKLAIEQKKEGAHILDINLGLPDIDEKEMMLKAVEAVSNLVDLPLQIDSSDPEVIE
AVLRQYNGKPIINSVNGEQSSMERILPIARKYGACVLGLTMDEKGIPEKAKDRLAIGKRIIHKAASMGIPKKNMLLDCLVLTASAQQEMVKETIKALELI
HSELQVPTVLGISNISFGLPNRELMNRTFLTMAFTAGLNTPIMNPSDQGMMDVVTSFRGLWGYDERCIQYVTKYNSKSAA-----PVA-KDK--G-EAL-
LKKMVVKGMKEEAAAATEELLKTL-DPMALVNDYLIPGLDIVGEEFETGEAFLPNLIFAAEAVQKSFEIIKSHL--SAEQIIKGRIVLATVSGDVHDIGK
NILKVILENYGYEILDLGKDVETERIVATVKKENIRLVGLSALMTTTVKNMAETVSQLHERCPETAVMVGGAVLNAEYAADIGADYYGKDAKAGVNIAQS
IFE
>tr|L1PYA0|L1PYA0_9FIRM Putative 5-methyltetrahydrofolate--homocysteine methyltransferase OX=649757 OS=Anaerostipes hadrus DSM 3319. GN=HMPREF0369_02046 PE=4 SV=1
--MLQNRLGK-ELLIFDGAMGTQLQNAGLSAGDIPEELNIDRPDLLRSIHKNYLKAGADFITTNTFGCNRLKMEEKYEAKDMLLAAVENARAARTEDSYI
VLDIGPIGQLLEPMGTLTFDEAYDIILEQVET-VKDQVDLVLFETMSDLYEVKAGVLAVKEHTDLPVFVTMTFENGRTLSGNDPETFINVAEGLGVDALG
VNCSLGPDELKPIIDEILEKASIPVMLQPNAGLPCL-EHGETHYHVTPEEYVESMKDYMARGAAIVGGCCGTTPEFIGKLAEAA-PKAVAERTV--EKKT
RVSSQTQTVTFG---DVIVCGERLNPTGKKKMKKALLEERYDELVVEAVKQVEAGAEVLDVNVGLPGIDEPETMKRVVRLLQEVVTLPLQIDSSEADAIE
NACRYYNGKPLINSVNGKDEVMEKIFPIAKKYGGVVIGLTLED-GIPLKAEERFEIAKKIVNKAAEYGIGKENIIIDCLTLTASAQQKEVKETLRAIKMV
K-KLGVHTVLGVSNVSFGLPNRPLLNRTFLALAMEAGLDLPIINPLDAELMGTIDAFHVLFYKDVDSQTYIKNQSKDKET-----KAAATTN------FT
LKDVIIHGLKDEVEKVTKEELKDK-EALTVINEVIIPALNIVGKDYETGKIFLPQLIQSAETTKKAFEVVKETFSAND-GEEKGPIIIATVEGDIHDIGK
NIVKVVLESYGYKIIDLGKDVKVEKVVEAYKKYKPKAIGLSALMTTTVASMERTIKALHEAGCSEPIWVGGAVVTEDIAHNIGADYYTEDAMAAVNLLEN
EIL
>tr|H1D1Y0|H1D1Y0_9FIRM Methionine synthase OX=742743 OS=Dialister succinatiphilus YIT 11850. GN=HMPREF9453_01618 PE=4 SV=1
------------MILFDGGMGTMLQKFGLEAGSCPDYYNISHPDVVQQIHRAYMEAGSQFITTNTFGSSPLKLADDLKVEEIAAAAVRNVRAACGKK--V
AGDMGPTGKFIKPIGDLSFDETCENYYRLAKALAQAGADCLIIETIIDIQEMKAALIAAKEAASLPVICQMTYSDGRTIPGTDPVTATILLDAMGADVIG
ANCSVGPDKLLEAARQMVSVTNKPVIIQPNAGMPVL-ENGETRFPLGPEEFASYAPEFAKIGVSYLGGCCGTTPDHIRKVAEVLKDVPLTLPPKV-KPFT
ALTSRTKTVFIGDDYAPVKIGERINPTGRKKMREDIQKGSFVSVKKEGLAEVAAGADVLDVNMGVPGIDQREAMETVISQLSMLCPVPLSIDSTDPAVLE
RALKVYPGRPLINSVNGDDEILEKVLKLAKTYGAAVLCLPLEKGNLPKTADERIRIASAIIDKALKAGLRKEDLLLDPLVLTIGSSDTGARETLKTISLY
KKEFGLPCVMGTSNVSFGLPARPRINAAFLTMAFACGMNAPIINPLDKDIQDAFINARLLLGFDPGARDFIRAA----AL-----SEEKKSA--PSPPLE
IKAAVKNGEKEESAALIKTLLDNGISSETIIKEGLTAAMTEIGDGYGAGKVYLPQVMMAAEAMQAAFKELKKIL--PEMSSAKGTLVIGTVKGDIHDLGK
NIVAALMENSGYRVIDLGKDVDPEVFVSAVKDHHADLAGLCSLMTTTLPEMEHTVKALKEETPGVKILVGGAVVTQDYASRIGAPNYCRDGIAAVKIADR
LTG
>tr|E2NUH8|E2NUH8_9FIRM Putative 5-methyltetrahydrofolate--homocysteine methyltransferase OX=451640 OS=Catenibacterium mitsuokai DSM 15897. GN= PE=4 SV=1
-M-FKERLTK-EWLFWDGGTGSVLQSWGLQAGELPETWNIIHPEKIVELNKGYLEAGCDIINTNTFGANRLKYPD--NLEEIVTKAVEHAKKARELAALI
ALDLGPTGKLLEPLGDLSFDDAVDIYAEVIEYGTKAGADVILIETMQDSYELKAAVLAAKEHSDLPVCATVVFDKGKMLTGGTPESVVALLEGLHIDALG
INCSLGPRQIKPFVERMIQVSSTPIIVTPNAGLPQT-DDGHTYYDMSADDFALEMKEIASLNVHVLGGCCGTTPEYLSKTIELVKDLPIEPPVK--KNMS
VVTSFSQSVEIGP--KPVIIGERINPTGKKKFKQALRDGDINYILSEGLKQEDAGAHILDVNVGLPEIDEPKMMVEVMKKLQSVIALPLQIDTSDPIALE
AALRHYNGKAMINSVNGKQESMDAVFPLVQKYGGVVVGLALDEDGIPDNAADRIRIAKKIYKEAGKYGIEPKDIVIDGLAMTISSDPTSAIATLETLRII
RDELHGHSILGVSNISFGLPQRPIVNANFFTMAMQSGLSCAIINPSSEAMMKSYRAYLALSGLDTNFTEYISAYGNSAPA-----TKSEAV-----D--S
LYESIKRGMSENAGKATKKQLESK-EGLEIINEELIPALDEVGKGFEKGTIFLPQLLMSAEAAKAAFAVIKDSMA--GKRKMKGKIIIATVKGDIHDIGK
NIVKVMLENYGYDVIDLGKDVPPEQIVDTAIQEDVKLVGLSALMTTTVVSMEDTIKLLKEKKPDTLTVVGGAVMTQEYAGRIGADCYAKDAMETVRFADK
VFG
>tr|J6IAY6|J6IAY6_9FIRM Homocysteine S-methyltransferase OX=936381 OS=Selenomonas sp. CM52. GN= PE=4 SV=1
------------IHIFDGAMGTMLQEGGLKPGGCPELMNLEQPDVVQKIHESYIEAGATMIETNTFGASALKLDHGLRVKEINEAAVKIAREASKRK--I
VGSLGPTGRFIVPLGDLEFEDAYQSFYEQAKTLADAGADYLLFETCIDIQEMRAGLLAAKDATSLPIICQLSYSDGRTVTGTDPQTAAITLEALGADIIG
VNCSLGPKELVPIVKTLAENCSVPISVLPNAGMPRL-ENGRTIFPMGPEEFASWGAKLVAAGATYLGGCCGTTPAHIKALAAAVKDLPLTERKSP-DNRL
RLTSRSKTVIIDKDLATTLIGERINPTGRKKLAEEIKNGSLFSVKREAIDQVRAGARLLDVNMGVGGIDQVKAMHDAIREVSQITDAPLAIDTSDTKTLE
AGLRAYPGRALINSVSAEKERIEEFLPLAKKYGAAILCLPITEDGVPKTAEDRINVINGIIKEAKKNGLKDGDFLLDALVMTISADQNACLEVLNTLRLY
RKHFGYPATMGLSNISFGLPNRPLINSTFFAMCLAAGLDAPIMNPYDEKMQEALMASAALLGKDPRGIDFSRNE----VN-----LKTKAAA--KPDVLA
IKQAVIDGASESIAMLTERAIREGHSSNEITEKALTAAMNDIGIDFGAGRVFLPQVLLSAEAMRASFQKIKELL--PAQEADKGTVVMATVKGDVHDLGK
NIVSALLSNSGFKLIDLGKDVDADTIVRTALEKEADIVGLSALMTTTMTQIDKVIKKLREAGSEARVIVGGAAVTEDYATSAGADAYANDGVSAVQIAKD
FVG
>tr|H3K967|H3K967_9FIRM Methionine synthase OX=742816 OS=Megamonas funiformis YIT 11815. GN=HMPREF9454_01790 PE=4 SV=1
------------IHIFDGATGTMLQKSVLKPGMCPELLNIEAPEAIQNVHRAYVEAGSNIVETNTFGASRIKLNENLKVEAINIAAVKNAKIATAKK--V
AGSMGPTGAFIEPLGELTFDEVYENYYEQAKILADAGVDYILIETCIEIQEMRAALLAAKDACDLPVICQLSFSDGRTVTGTDPQSAAIILEAMGADIIG
ANCSLGPEQLVPIIKELADNCSCPISVQANAGMPHL-ENGQTIFPLTPEDMAKWAPKLVEAGATYIGGCCGTTPAHIKAIKEALADVSEPIRKTP-NPNL
ALASRSKTVFIGKDLPTRLIGERINPTGRKKLAEEIKNGSFISVKREAIEQTQAGAQILDVNMGVAGIDQAKAMHKAITEISQLVNTPLAIDTSDVKALE
AGLKAYPGRALINSVSAEPDRLKYFIPLAKRYGAAILCLPLSDEGIPKTAKERLALAQKIIAEAKAQGLKDNNFLLDALVMTIAADKNACNEVLNTLKLY
REHIGAPSTMGLSNISFGLPNRPLINSTFFTMCLAMGLDAPIMNPYDDSMQNALSASNALLAKDPNGRDYSLNH----SG-----QNIVKAN--AVDIIE
IKSAIISGEKESIAQMVEQALTEGHKTNEITDKALSAAMNVVGKDFGAKKIFLPQVMLSAEAMREAFIKIKERI--PADVSNKGTIVIATVKGDIHDLGK
NIVSALLENNGFKVIDLGKDIDKEEIIKAAIDNKADMIGLCSLMTTTITQIDEVIAELNKSEYSTKVMIGGAVVTQEYADNVGADAYAPDGVEAVEIAKK
LIN
>tr|B1BN91|B1BN91_CLOPF 5-methyltetrahydrofolate--homocysteine methyltransferase OX=445334 OS=Clostridium perfringens C str. JGS1495. GN=CPC_1653 PE=4 SV=1
-----------MIKIFDGAMGTILQKLGLKLGENPEVLNIYNEEVICDIHRRYIDVGANFITTNTFGANRKKLVNDFKVEEIISKALKIAKRARGE-VKI
ALDIGPIGELLEPMGTLSFDEAYDIFKEQVIVGVENGADIILIETMSDLYEAKAAILAAKENSSLPVFCTMSFENERTFTGCIPESMAMTLEGLGVDALG
VNCSLGPREMESVIKRIAKSTNKEIIVQANAGMPSI-DRNSTSYEVNKYEFAEYGKKFVDLGANYIGGCCGTTPEYIEELSKKLKNKESIKRGK--VSLT
GVCTPSLTIKEK---GVYVIGERINPTGKKRFKEALKNNDIDYIVKQGIEQVEAGASILDVNVGIPEVDEKNLMVKIVKNLQSVLDTPLQIDSSNPEVIE
KALRYYNGKCILNSVNGEEGTLDKILPIVKKYGTMVIGLTLNNKGIPKSCKEKLEIGKKIIEKASEYGISKDNIILDPLILTAATNQTEVKETLRTIRKI
KEELGVKTTLGVSNVSFGLPERENINEVFLGMALNEGLDFPIVNPNKEGIMKVIRGFELLYGYDKGANNYVKYYSNKNNI-----HKEKENV--E-NILT
LKEIVIKGLKGEAKEKTKELLKSI-KGMEIVNKELIPALDIVGEKFEKEEIFLPQLIASAETVKESFEVIKSSIDFSKNK-NNGCIVLATVKGDIHDIGK
NIVKVILENYGYDIIDLGKNVEPEEILKVCTEKDVKLLGLSALMTTTLGSMEATIKKVKEKGLKTKIFVGGAVLTKGYAEKIGADFYAKDANRAVEIAKV
VFR
>tr|B0MQG9|B0MQG9_9FIRM Putative 5-methyltetrahydrofolate--homocysteine methyltransferase OX=428128 OS=Eubacterium siraeum DSM 15702. GN= PE=4 SV=1
-MEIKTLLQR-GLLIFDGAMGTQLQAKGLKTGETPELLNLTAKDLLKEIHRSYIDAGADIISANTFGANSYKLSHGKSVDEIITAGIINCKEAIKE-VFC
ALDIGPIGQLLEPTGSLKFEEAYDIFREEIVAGYKAGADVVLFETMTDLYELKAAILAAKENCDLPIICSMTFENGRTFTGCPAEAEILLCEGLGVSAVG
VNCSLGPKELMPIIKTLCEKSKIPVIVMPNAGLPDP-ATG--EYSIDAEEFSDYAVEIADLGAGIIGGCCGTTPEFIRRTAEKVKGRKYESKKI--ERVC
TICSGTNVVEVS---QPRIIGERINPTGKKLFKQALINDDIDYILGQAIEQVGAGADILDVNVGLPDIDEKAMMIKAVKSIQGVTNVPLQIDSTIPEVLE
AALRVYNGKPMVNSVNGEEESLKNVLPLVKKYGAAVVGLTLDKDGIPPKAEQRVAIAEKIIKRCEKIGIPKEDIAIDCLTLTASAEQLAVNETLKAVRAV
KERFGVRTVLGVSNISFGLPNRELLNHIFLTMALENGLDLPIINPNVASMTGAVRAFKLLKAIDVNSVEYIAAYGSDTPT-----AVAKP-K--S-SEV-
LEYAIDNGLKADAAKITEQLLIDT-DPMVIINERLIPALDKTGTLFEQGKIFLPQLILSAGVAQSCFDVIKAHLAKNNETVSKGKIVLATVKGDVHDIGK
NIVKVLLENYGYTVIDLGKDVEYQAVVDAARKHEVKLVGLSALMTTTLKSMEETIKLIRDNGLPCKVVVGGAVLTPEYAEKIGADFYAKDAKETVDIAKK
VIG
>tr|A6TTI3|A6TTI3_ALKMQ Homocysteine S-methyltransferase OX=293826 OS=Alkaliphilus metalliredigens (strain QYMF). GN= PE=4 SV=1
-MNFLRDCKE-GMLIFDGAMGTMLQKSGLKVGALPEIYNIEHPELIQQIHERFVRAGAQVVTTNTFQANELKLKDIYSLEEIIEGGIKVAKAS---APYV
ALDIGPLGQMMKPLGEISFDRAYDIFKRQVQAGVKAGADCILIETISDLYEAKAAILAAKENSDLPVLCTMTFQDGRTFTGTDPMTATLVLQSLGVDALG
VNCSLGPKEMLPILSDILKYAKVPVMVQSNAGLPRL-EGDDTIFPASPEEFALYGREMAELGVGILGGCCGTTPEHIQALKKAVFQINSPERKV--ERVT
CACSPTKTVILD---GTTVIGERINPTGKKRLKEALRNNQLEVLVAEAIDQSNAGAQVLDVNVGLPEIDEVAVLKEVIMGIQEVVDTPLQIDSVNVEAME
AAARIYNGKPIINSVNGKEAVMAAVFPIAKKYGATLIGLTLDDKGIPETAEERIQIAKTIMERAKAYGIPKEDLIIDCLVMTASAQQSVVKETIKAVSLV
KSELGLKTSLGVSNVSFGLPNRELLNRTFLATALAAGLDAPIMDPLSKEMMDTIEAFRVLNNEDQEAMAFIRRFK--NNT-----KSIEAPV--Q-SSKD
LKTMIIEGRKTEVAAAVDLLLQNE-SPFEIIETYFIPALDQVGKEYEVGDLFLPQLLRAAETVKAGLAVIKASSFE--MELDRGSILLATVKGDIHDIGK
NIVKMLMENYGFQIIDLGRDVDPQLIVETIKKNNIRLVGLSALMTTTVKNMQLTIKMIKEEAPHCKVMVGGAVLNEEYAQMIGADYYTVDGQAGIRIAKA
FF-
>tr|D4S1Z9|D4S1Z9_9FIRM Vitamin B12-dependent methionine synthase family protein OX=511680 OS=Butyrivibrio crossotus DSM 2876. GN=BUTYVIB_02121 PE=4 SV=1
-M-ILDELGR-RILFFDGGLSSLLQERGLEPGELPETWNLTRPEILIDIHKAYINAGADIINANTFGANRFKFD---NLEEIITAGIANAKKAVAEKAYV
ALDIGSCGKLLKPMGTLDFADAVDVFAEIVRIGDKAGADLILIETMSDTYELKAAVLAAKENSDLPVFATVIFDSHKMLTGATPAAVVALLEGLNVDAIG
MNCGLGPEQMKPIFEEMAEYASVPLIINPNAGLPRS-ENGRTVYDVGPEEFAGYMELLVKDGAWIIGGCCGTTPEHIMATYDRCKDLKPIPIVE--KDIT
LVSSYSHAVEIGK--VPVIIGERINPTGKSKFKQALRDHNMTYILEEGTKQADSGAHILDVNVGLPEIDETAMMKDTVFELQSILDLPLQIDTTDMNAME
TAMRIYNGKPMVNSVNGKKEVMEQVFPLVKKYGGAVVALCLDEDGIPDTAEGRIKIAEKIYATAATYGIKAKDIVIDALTMTMSTDNESANITLDTVREI
KAR-GGRTVLGVSNISFGLPQRELITSTFFTMALQAGLSAGIINPNAKAMMQSYDTYMVLSGNDSQCTKYIEKYAVAPET---------------AKNFS
LSDCIVKGLKENAYTETVELLKTK-APMDIINGDLVPALDIVGKGFEKGTMFLPQLLMSAEAAKAGFEAIKEYMKKSGSEEKKATVVIATVKGDIHDIGK
NIVKVILENYSYNVIDLGKDVPPEDVVDAVIANDAKLVGLSALMTTTVVNMEATIKLLREKCPDCKIMVGGAVLTQEYADMIGADFYGKDAMQSVYYAES
LFN
>tr|H1LV04|H1LV04_9FIRM Putative 5-methyltetrahydrofolate--homocysteine methyltransferase OX=861454 OS=Lachnospiraceae bacterium oral taxon 082 str. F0431. GN=HMPREF9099_01290 PE=4 SV=1
--------MH-NLLILDGAMGTMLQAAGMKAGEHPEVFGFDNPDIVKNIHLKYIEAGSNIIYANTFGANAHKLEGKIDVDTAIKTAIQSAKEAVA-RVKV
ALDIGPIGELLEPLGVLRFEDAYDIYKEMVVAGEKYGADIIVYETFTDLYDVRAGVLAAKENTKLPVWVTMTYETGRTFTGTKIESMAVTLEGLGVDAIG
FNCSLGPKEIFPLAKKLKEWTTLPIIIKPNAGLPNP-STG--EYDLHAADFAKLMAEYKSLGISYAGGCCGTAPDFIKELKSELDATKEGKSV---KVKT
GICSANEMVELN---GVRVVGERLNPTGKKRFQEALLNHEMEYICKVAIEEEESGADILDINVGVPGGDEVALMREAVKAVQSVVNIPLQIDSSNPEAIE
AGLRVYNGRAIVNSVNAEDERLDLILPIVKKYGAAVIGLALNENGLPTTAKQRVDNASHILERCLEYGLKKEDVIIDCLTLTVSAQQDQARETLEAVRMV
TNDLGLHTTLGVSNISFGLPARSHITENFLIQAMYAGLDLPIVNPNIEGIMNAIYSFKVLSGEDKDSVKYIERFAT----------VVTVSN--N-GEVT
VEDAILKGLKEETYNNAKKLLETK-GELEIINEYLIPALDTVGDLYEKQVIFLPQLINAANAASSAFELIKERIANKGHNVSKGKIVVCTVKGDIHDIGK
NIVKVILENYGYRMIDLGRDVDIKNVVDTVVRENVKLVGLSALMTTTLPAMKKTIEEIRKVSNDCKVWVGGAVLTKEYADEMGADFYAPDARSSVDIAKT
VLG
>tr|F4A5B5|F4A5B5_CLOBO 5-methyltetrahydrofolate--homocysteine methyltransferase, putative OX=929506 OS=Clostridium botulinum BKT015925. GN=CbC4_1990 PE=4 SV=1
-IDINKFLLK-KHIFFDGAMGTMLQNRGISLGEVPEIYNILNPKVIKDIHKKYIDAGVDIITTNTFGANELKLKDGYSVEKVIEAGVKLAKEVSNG--LV
ALDIGPTGEMLEPMGDLKFERAYEIFKSQVIAGVNAGCDIILIETISDLYEAKAAILAAKENSSLPVFCTMTFGDGRTFTGTDPITMVSVLEGLSVDALG
INCSLGPKEMLPVMEKIIKYSSIPVIAQPNAGLPRV-VDGKTIFDITPEEFAFYQKQMASLGVSILGGCCGTTDKYIKVVIDELKNSIPKKILK--KDKT
MISSYCKTVILE---GIKVVGERINPTGKEEFKEAIKSNNISYILNEAISQRACGAHILDINVGLPGIDEKDIMVKTIKNLQSTVDIPLQIDSADCDVIE
AATRIYNGKPIINSVNGKQESMKNIFPIVKKYGACVIALTLDENGIPTTIEDRVKIAEKIINTAKEYGIDKKDIIVDCLVLTASAQQKEVMETLDALGII
KEKFKVKTILGISNISFGLPKRELMNRTFLTMALTKGLDVPILNPNDRDIMETIKSFEVLANIDTNCENYIGEISNLKKE-----V---KYN--N-KKIN
LKDIVVNGVLDEVENVTKELLKTK-DGVEIIEKYLIPALDLVGNDYEEGKIFLPQLIKCGETVKKSFQIIKDNIKKYNKDVVKGKIVLATVKDDIHDIGK
NIVKLLLENYGFEVVDLGKNVSVETILEVVKKYNIKLVGLSALMTTTVKSMEETISRLKEVNPICKVFVGGAVLNEEYAKQIGADYYAKDARESVLIANE
IFK
>tr|E9SG66|E9SG66_RUMAL Putative methionine synthase OX=246199 OS=Ruminococcus albus 8. GN=CUS_7787 PE=4 SV=1
-MGFRELLQK-EFVILDGAMGTMLQAKGLKMGETPEVMNIEKPEWLMDIHRQYIEAGSDIIYANTFGANRHKLAKGFSVDKIIGEGIKLARKAVEG-TLV
ALDIGSIGQMLEPTGTLTFEEAYDIFKEMVIAG--READLVVFETMTDLYEFKAAILAAKENSDLPIMCTMTFENMRTFTGVDISAMCLTAEGLGVDAVG
VNCSLGPKELYPVVEKICQWTNLPVVVKPNAGLPDP-VTN--EYNCSAEEFAEFAEALIPLGIKVIGGCCGTDPTYIACLKKMLDGKKCVQRNV--HIPA
VCCSATDVVVID---QPRIIGERINPTGKKRFKQALLEGDIDYILGQAIEQIDAGADILDVNVGLPAIDEKAMMVKAVKALQGVVDVPLQLDSTIPEVME
AALRVYNGKPIVNSVNAEEKSLNTVLPLVKKYGAAVVGLTLDENGIPKTADERFNLAKKILDRAMAIGIRKEDVYIDCLTLTASAEQENVMQTVNAVRRV
KEELGLRTVLGVSNISFGLPSREIVNHNFLMMCLTSGLDLPIMNPNIASMTATVRTYKLLTNIDKNSVDFIAHYGGDTSS-----PMQKAEK--K-SDI-
LPYAIEHGLKGEGAEITAKLLETT-DSMVIINEMLVPALDKAGEQFEKGKIFLPQLIQTAGVAQACFEVIKQKMLADGNSVSKGKIILATVKGDIHDIGK
NIVKVLLENYGYEVIDLGKDVDYQTVVDAAIENDVHLVGLSALMTTTLVSMEETIKLLRANNVDCKIMVGGAVVTPDYAEQIGADFYSKDAKQSVDIARQ
VFG
>tr|C5VTW2|C5VTW2_CLOBO MetH1 OX=592027 OS=Clostridium botulinum D str. 1873. GN=CLG_B0011 PE=4 SV=1
-IDINKILLK-KHIFFDGAMGTMLQNRGISLGEIPEIYNILNPKVIKDIHKKYIDAGVDIITTNTFGANELKLKDGYSVEEVIEAGVKLAKEVSNG--IV
ALDIGPTGEMLEPIGNLKFNRAYEIFKRQVIAGVNAGCDIILIETISDLYEAKAAILAAKENSELPVFCTMTFGDGRTFTGTDPLTMVSVLESLSVDALG
VNCSLGPKEILGVVEEIIKYSSIPIIVQPNAGLPRV-ENNKTIFDITPKEFAFYGKVMANKGVSILGGCCGTTDEYIKEVVKNLKYNVPLKIIK--KNIT
MVSSSSKTIILE---GIKVVGERINPTGKKEFREALKNNDINYILKEAISQKKSGAHILDINLGLPEINEKDIMIRTIKELQGTINVPIQIDSSDTKVIE
AAVRICNGKPIINSVNGKEESMKSIFPIVKKYGTCVIALTLDENGIPNTIEDRVKIAEKIINTAKTYGIDKKDIIVDCLALTASAQQKEVMGTLDALEII
KKQFKVKTLLGISNISFGLPKRELINRTFLTMALTKGLDVPILNPKDREAMETIKSFEVLANIDKNCENYIKEIDDFKKE-----K---IDT--R-EKMD
LKHLVISGLTEDVLKMTKTLLDKK-NGIEIMDEYLIPALDEIGKEYEEGTIFLPQLIKCGETVKEAFNIIKKHMDKKNDTVIRGKIVLATVKDDIHDIGK
NIVKLLLENYGFEVIDLGKNVSVERILEVVKKHNIKLVGLSALMTTTVKSMEETILKLKETIPLCKVFVGGAVLNKEYAKQIGADYYAKDARESVFIANE
VFK
>tr|E7G958|E7G958_9FIRM Homocysteine S-methyltransferase OX=469596 OS=Coprobacillus sp. 29_1. GN=HMPREF9488_01296 PE=4 SV=1
--MLRERLGK-DLLIFDGAMGTQLQEAGLKAGEIPEVYNIEHPEIIIDIHSRYLQSGANFITTNTFGCNPLKMADGYCYCDLLKAAVKNARIARDKPAYI
ALDIGPIGQLLEPLGTLTFDEAYEMIASQILI-VKDQVDVVLLETMTDLYEVKAAILAVKENSDLPVFVTMTFENKRTLTGTDPLTFVNVVEGLGVDALG
VNCSLGPNELKPIIDEILEVSSIPVMIQPNAGLPCL-HNGQTCYEVTSDEYALAMIDYMQRGVSIVGGCCGTTPDFIAELKKRA-PQNVTSRDV--KRLT
RVSSQNQTVTFE---GVVVCGERLNPTGKKKLKAALKEERYDECVVEGIKQQQAGADVLDVNVGLPGIDEPATMVKVMKLLQEVINLPLQIDSSSPEAIE
KACRYYNGKPLINSVNGKDEVMEAIFPIVKKYGGVVIGLTLED-GIPLYAHERLAIAKKIIDKASEYGIAKEDIIIDCLTLTASAQQKEVQETLKALTLV
K-ELGVHTVLGVSNVSFGLPNRPLLNRTFLALAMQSGLDLPIINPLDQELMGTIDAYNVLYHFDKDSSRYISKQSQVTTL-----A-LTTSS------FT
LEDMIIHGLKDEVQAKTKELLQER-EAMDVINNVIIPALNRVGKDYETNKIFLPQLIQSAETTKKAFEVVKSTFRVDS--QSKGPIMMCTVEGDIHDIGK
NIVKVVLESYGYQVIDLGKDVKVEKVVEAYHKYQPKMIGLSALMTTTVVNMKKTIEALHKVNCQCPIWVGGAVLTQEIADEIGADYYSEDAMASVTLLNH
IFR
>tr|H1C6N3|H1C6N3_9FIRM Methylmalonyl-CoA mutase domain-containing protein OX=658087 OS=Lachnospiraceae bacterium 7_1_58FAA. GN=HMPREF0995_00111 PE=4 SV=1
---MGIEIQN-KFLILDGAMGTVLQQRGLSPQGRPELLNLTEPELLDSVYKEYIAAGSQVIYANTFGANGLKLAKGHSVEEVVGAAIAVAKKAAAG-TLV
ALDVGPLGELLEPMGTLSFERAYDLFREMAEAGAKAGADLIVVETMTDLYEAKAALLAAKEAAHLPVFVTMSFDGGRTFTGCTVASMARTLEGLGADAIG
LNCSLGPDLLAPLLKELCENTRLPVIAKPNAGLPDP-VDG--HYDMGPEDFAQALLTCVEAGISIVGGCCGTSPEYIRRLTAVLEGKKPVSRHY--NNTG
LVCTPVTPIRLN---GVRVIGERINPTGKKRFQQALLENDLDYILDVGVQQEDAGADILDVNVGFPGVNEVVMLPRVVKKLQSAIAVPLQLDSSNPDALE
AGLRVYNGKAAVNSVNGEPEVLERVLPIVKKYGASVVGLTLDKNGIPKTAEERVAIARRILQAALDHGIPREDVWIDCLTLTVSAQQEQAAETLKAVRTI
REELGLQVVLGVSNISFGLPNRKLITQNFLIQAMHAGLTLPIINPNQTEMMDAVAAYRVLSGEDRECRAYVARFAA----------VQAAPK--A-DAL-
LGDAVIRGLKADAGKLAAKALETE-DELSLVENHLIPALDKVGEDYDKGTAFLPQLLSAAQAAQAVFEVIRSSIAAKGVPVKKGKLIVATVQGDIHDIGK
NIVKTVLGNYGYEVLDLGRDVPPETILRTVQEQGVRLVGLSALMTTTLPAMEKTIRLLHTMEEPPVIFVGGAVVTPEYAKQMNADYYAKDAHQSVEITRK
VMG
>tr|G1VT53|G1VT53_9FIRM Putative uncharacterized protein OX=457422 OS=Erysipelotrichaceae bacterium 2_2_44A. GN=HMPREF9022_03184 PE=4 SV=1
-METEDRI-----LFLDGAMGTQLQANGLPAGASPEIFMMEHGNIIEEIHAAYIDSGSDIIYTNTFGANAKKLTKRYTVEEIVTTAVQLAKSAAKR-VRV
ALDIGPIGELLEPNGYLPFDDAYDLFAEQVIVGEKAGADLIVFETMSDLYEVKAAILAAKEHTRLPVFVTMSFEDHRTFTGCTTASFALCAEGLGADAIG
INCSLGPDQILPIAEELAAMSNLPLIIKANAGLPDP-VTN--TYSINASGYAQMLTAFTKLPVTYVGGCCGTTPQFIRELKKTLETIDLSLRKQ--RSGS
YACTPTKCLHIQ---DVHVIGERINPTGNKRMKAALLEHRMDEILAIAMEEVAGGADILDVNVGLPGIDEKAMMVEVIGELQSVIDLPLQIDSTDPDVIE
AALRAVNGVAIVNSVNGEAGVMERILPSVKKYGANVVGLTMDEGGIPQSARERLVIGTRIVETAERYGIARDRVFLDCLTLTVSAQQSGARETLQALTDI
RSQLGVHTVLGVSNISFGLPSRITLNQNFLTMAMQAGLSMPIMNPNQTAMMDAVRSYRVLYGIDIDSQEYIRIYAQQKKA-----EMKPASA--S-SQA-
IEDSIMHGLKEETRHQCCELLKMK-EPLQIVNEHLIPALDAVGSRYEKKEIYLPQLINAATASQCAFEEIRKHMQSSGESISKGKIILATVKGDVHDIGK
NIVKVVLENYGYQVFDLGKDVAVEAVVETAIKEQVRLIGLSALMTTTLKSMEDTITALHESGHDCKIMVGGAVVSPEYAKQIHADYYAKDAKESADIARE
VLG
>tr|E4LRC5|E4LRC5_9CLOT Putative 5-methyltetrahydrofolate--homocysteine methyltransferase OX=908340 OS=Clostridium sp. HGF2. GN=HMPREF9406_0215 PE=4 SV=1
-MEIENKI-----QFLDGAMGTQLQDKGLPAGASPELFMMEHGEIIEDVHAAYIDSGSDIIYTNTFGANAKKLCKQYTVEEVITRAVQLAKSAAKR-VQV
ALDIGPIGELLEPNGYLPFEEAYELYRQQVVAGEQAGADLVIFETMSDLYEVKAAILAAKEHTQLPVFVTMSFEDHRTFTGCTTASFALCAEGLGADAIG
INCSLGPDQILPIAEELAAMTNLPLIIKANAGLPDP-LTN--TYSIDAAAYARMLLPYTKLPLAYVGGCCGTTPQFIQELKNTLTTIAVEKRKR--RIGS
YACTPTKCLHIQ---DVHVIGERINPTGNKRMKAALQEHRMDEILAIAMEEVEGGADILDVNVGLPGIDEKEMMVEVIKELQSVIDLPLQIDSTDPAVIR
AALRAVNGVAIVNSVNGEAAVMESILPAVKKYGANVVGLTMDEDGIPACAQKRLEIGTRIVETAQRYGIAKERVFLDCLTLTVSAQQSGAKETLQALTAI
REQLGVHTVLGVSNISFGLPSRILLNQSFLTMAMQAGLSMPIMNPNQAAMMDAVRSYRVLQGIDVDSQEYIRIYAQQKRE-----GGKPHIE--S-VHI-
IEESIMRGLKEETRQLCTKLLSEK-EPLQIVNEHLIPALDAVGARYEKKEIYLPQLINAATASQCAFEEIRRSVQAGGESISKGKIILATVKGDVHDIGK
NIVKVVLENYGYQVFDLGKDVPVETVVETAIKEQVRLIGLSALMTTTLKSMEETIQALHESGHECKIMVGGAVVSADYAKQIHADYYARDAKESADIAKE
VLG
>tr|D4LF38|D4LF38_RUMC1 B12 binding domain./Pterin binding enzyme./Homocysteine S-methyltransferase OX=213810 OS=Ruminococcus champanellensis (strain DSM 18848 / JCM 17042 / 18P13). GN= PE=4 SV=1
-MTFAELLN--NYIFLDGGMGTMLQANGMQAGERPELLNLKDPALVEQVQRAYVEAGSNIICSNTFGANRAKLTGGATVQQVIPAAIQCARRAAAG-ALV
ALDLGPTGQMLEPTGSLTFEQAYDLYAEQVDAGQE--ADLILIETMTDLYEIRAAVLAAKEHGNKPVIALMTFETGRTFTGCSVSAMALTLEGLGVDAMG
INCSIGPDELYPVVEELCRWTTLPLLIKPNAGLPDP-VTN--QYNVSPAEFARSMTRIAKLGVKLLGGCCGTTPDYIRAVREAVADLPFTPRQV--QVPA
AVCSYSRTVVID---RPRVIGERINPTGKKLFKEALLRGDIDYILGQAITQVHGGADILDVNVGLPSIDERDMMVRTVKALQGVVDVPLQLDSTMPQVLE
AALRIYNGKPIVNSVNGEEKSLSTVLPLVKKYGAAVVGLTLDEQGIPKTAEGRFQIAKRILDRALALGIRREDVYIDCLTLTVSAEQDGAVQTLSALHRV
KQELGLKTVLGVSNISFGLPNRELVNHSFLLMALQNGLDLPIMNPNVASMMDAVRSYCLLANIDKNAVDFIAAYGS---P-----KAKPAAA--P-ADM-
LSFAIENGLKQEGARITRQLLEQM-DSMEIVNGQLIPALDKAGAAFEQGKLFLPQLIQAAGVAQAAFGEIRSYLTAHNVPVSRGKVILATVKGDIHDIGK
NIVKVLMENYGYQVIDLGRDVPPETIVAAALEHQVKLVGLSALMTTTLGAMEETIRQLHANNVPCKVVVGGAVLTADYAAQIGADYYAKDAKESVDIAKQ
VVG
>tr|E8LFR4|E8LFR4_9FIRM Putative 5-methyltetrahydrofolate--homocysteine methyltransferase OX=626939 OS=Phascolarctobacterium succinatutens YIT 12067. GN=HMPREF9443_01706 PE=4 SV=1
-M-FKELLGK-QMLFFDGATGTQLQARGLQPGELPESWNFTHPDIVEAVHRSYLDVGSNIVKSNTFGANPLKL--GLDCKETIEAAVAIAKKACGGNKFV
ALNLGPTGKLLAPYGDLPFEKAVEAYGEMVRYGAAAGADLILIETMSDTYEIKAAVLASKENCDLPICVTMTFDDGKLLTGATVEAAALMCEGLGVDAIG
FNCGLGPVQVGKLFPQMLEATSLPLIINPNAGLPVQ-RDGKTCFDVGPEEYAELMYELAGKGASIVGGCCGTTPEHIAQMIAKCKTLQPGGTRD--CRLT
AVSSYGKAVHLGE--GPVIIGERINPTGKKRLKEALVNGDLDYVCRLGLEQIGVGAQILDVNVGTPGIDEAAMAAKAVPALQAITDTPLQIDTSNYEAME
RALRLYNGKPMLNSVNGKEDSLQHVLPLAKKYGAVLVALCLDDSGIPATAAGRIAVAEKIIARAAEYGIESRNIVVDPLALTISTGAENAAIACEVIRTM
KAR-GINTVMGVSNISFGLPGRDAVNSTFFSMAMAAGLSCGIINPQSKPMMDAYYGYRALAGYDEGCKEYVQHYADAP--------KAAATT--VS--MG
LYDAIVKGLQGPARQAAAKALESE-KPLDIINKYMIPALDFVGHGFEKKTLFLPQLLMSADAAKAAFEVIREAV---GVETQGETVIIATVHGDIHDIGK
NIVKVLLENYGYRVLDLGKDVPVEAVVEAAKKTDAKVVGLSALMTTTVGAMEETIAALHNEC-DCQVVVGGAVLTQEYADTIGAEHYAPNAVSAVNYVNE
ILG
>tr|B1C150|B1C150_9FIRM Putative 5-methyltetrahydrofolate--homocysteine methyltransferase OX=428126 OS=Clostridium spiroforme DSM 1552. GN= PE=4 SV=1
--MLQERLKK-EILVFDGAMGTQLQAAKLKAGEIPEYLNITDPYLIQKIHLDYLNAGANFITTNTFGANPLKLKDPYQYNEIIETAINNAIIARKKNSYI
VLDIGPIGQLLEPMGTLTFDEAYEIIKKQVLI-AKDKVDAILLETFTDIYEAKAGILAVKENSNLPVFVTMTFENLRTLSGCDPITMVNVLEGLNVDVLG
VNCSLGPIELTPIINDILKVATVPVMIQPNAGLPCL-VEGKTCYNMDIDTFVSKSIEHVKNGVRIIGGCCGTTPEFIARLKDAL-PEKITLTKP--VIAT
RVSSGNQTVEFG---HIVVCGERLNPTGKKKLKLALKEERYDELIVEAIKQDQAGAHVLDVNVGLPGIDEVSTMKKVIKLLQEVISLPLQIDSSNPEAIE
QACRYYNGKPLINSVNGKMETMEAIFPIVKKYGGVVIGLTLDENGIPSMAKDRYEIAKKIIATAKKFGISKENIIIDCLVLTVSAQQKDVIETIKAVKMV
K-ELGVHTVLGVSNVSFGLPNRPLLNKTFLTMAMTNGLDLPIINPLDQELMAAIDAFNVLFNYDHDATNYIQKQSNQTIT-----SQSKPSD------FS
LNDIIIHGLKEEVINATKKQLEKQ-PGLQIINQILIPALDTVGKQYENNIIFLPQLIQAAETSKIAFGVIKETFK-ET-SATKGPIIMATVHGDIHDIGK
NIVKVVLESYGYKIIDLGKDVPPETIVEAYHRHQPKAIGLSALMTTTVVSMEKTIALLKEIDNMCPIFVGGAVLTADFAKEINADFYVKDAMDTVELMNK
IV-
>tr|G9RXZ5|G9RXZ5_9FIRM Methionine synthase OX=665956 OS=Subdoligranulum sp. 4_3_54A2FAA. GN=HMPREF1032_01146 PE=4 SV=1
---MNKIFGK-RYWLLDGAMGTMLQKSGLKLGERPDLLSITHPDVVERINRAYVEAGSDLICANTFGSNAKKLAGGYTVEEVVAAGIGTAKRAAAG-ARV
MLDVGPIGELLEPAGALKFEEAYEIYKEVVLAGWRAGADLVKFATMTDLYEIKAAVLAAKENTPLPVLVSMTFENGRTFTGCTVESFAITAEGLGVDGVG
INCSLGPAEIYPMAQRLCAATSLSVFIKPNAGLPDP-ATG--RYSIGPKEFCDELERFKALGISAVGGCCGTTPEYLALLAKTFKQDTPVHREP--VRRS
AVCTPTRTVEID---TVRVIGERINPTGKKRFKEALRDGDMDYILSQAVEQAGAGADILDVNVGLPEIDEQEMMIRAVKAVQSVCDLPLQLDSTRADVLE
AGLRVYNGKPIVNSVNGEQAVLDRLLPICKKYGAAVVGLTLDENGIPALAEQRFALAQKIVAAAEAAGIPREDVYIDCLTLTASAQQEAVRETLKAVRMV
KERLGVKTVLGVSNISFGLPCREQVNTSFLTLAMAHGLDLPIINPNAEAMMAAVASFKVLYNIDRDSREYLARYAGAAQQ-----TVT------------
LYDAVLQGLKAAAAQAARTALQAK-SPEELVNEVLIPALDTVGAGFEKGVLFLPQLLQSAGAAQAAFEVVKDAIAASGKSGGKGKIIVATVKGDIHDIGK
NIVKTLLENYGYDVLDLGRDVPAETVVKAAQEHGVRLVGLSALMTTTLGSMEETICALRRAGLSCQVMVGGAVLTPEYAMHIGADYYAKDAKQSVDIARE
VLG
>tr|C0ECI7|C0ECI7_9CLOT Putative uncharacterized protein OX=537013 OS=Clostridium methylpentosum DSM 5476. GN=CLOSTMETH_01558 PE=4 SV=1
-MDVREYLKD-HILVFDGAMGTMLQNKGMQVGDLPETLNFTHPELVTEIHREYVEAGSDVVSANTFQANEFKLHGGYTVEQVITQAVKLGKQS---AKFV
ALDVGPLGQLVEPMGTVKFETAYELFRQQVVTGERAGADLIIIETMSDLYETKAALLAAKENTSLPVIVSLTYQDGRTFTGTDPITGTITLQSLGADAVG
VNCSIGPDDLIPIVEQILTYAQVPVIMQANAGLPKI-EDGKTVYDVHAEEFAEAVSRMMDRGVRIVGGCCGTDPDYIRLLRKKADGMKPVATNP--KRVT
AVTSGTRTVVLD---RVTVIGERINPTGKKRLKEALRENRMDYIVGEAINQANAGADVLDVNVGLPEIDEPAMIARAVKEVQGVTNLPVQVDSSDPAAIE
SGVRACNGRPIINSVNGKAENLAAVLPIVKKYGAVVVGLTLDEDGIPATAEGRFAVAKRIVETAAEYGIPKEDILIDCLTLTASAQQEQVLATLDAIKLV
KERLGVKTVLGVSNVSFGLPSRPLLNSVFLAAAFGAGLDAPILNPLSKEMMDAVNTFRVINYQDRDAVRYIDRYA--NAQ-----PAQQAAV----GEIS
LKEMIVQGRKEEAPAKVRELLQTT-PALEVIDSHFVPALDIVGQRYEKGEIFLPQLMQSAETVKASFEVIKASMDA--ETQSKGRVIVATVLGDIHDIGK
NIAKMLLENYGYDVIDLGKDVPIETVVQTAKEQDIQLIGLSALMTTTVKNMKDTISAIRGAGLNCKIMVGGAVLNEEYAEFVGADFYVKDGRESVELAQS
IF-
>tr|B0MEJ4|B0MEJ4_9FIRM Putative 5-methyltetrahydrofolate--homocysteine methyltransferase OX=411490 OS=Anaerostipes caccae DSM 14662. GN= PE=4 SV=1
--MLLDRIGK-ELLIFDGAMGTQLQEAGLRAGDIPEELNIDRPELIVSIHEKYLGAGADFITTNTFGCNELKMQEKYEYRDMLRAAVSNANEARKNQAYI
VLDIGPIGQLLEPMGTLTFDEAYDIILSQVET-VKHDVDAVLFETMSDLYEVKAGILAVKENTSLPVFVTMTFENGRTLSGNDPVTFVNTVQGLGADMLG
VNCSLGPAELGPIIEEILSVSSVPVMIQPNAGLPCL-EHGETHYHVTSDEYAELMQGYLKDGISAAGGCCGTTPEFIRKLKAAS-PKKAAPRKI--EKKT
RVSSQTKTVTFG---DVIVCGERLNPTGKKKLKLALKEERYDELVSEAIKQDEAGADVLDVNVGLPGIDEPETMKHVVKLLQEVITLPLQIDSSNARAIE
LACRYYNGKPLINSVNGKDEVMEAIFPIVKKYGGVVIGLTLDE-GIPLKAEERFEIAQKIIAKAAEYGIGKEDIIIDCLTLTASAQQKEVKETLKAIEMV
K-KLGVHTVLGVSNVSFGLPNRPLLNRTFLALAMQAGLDLPIINPLDKELMGTIDAFHVLFYKDIDSESYIRNQSNAAET-----KAAVQTE------FS
LHDIILHGLKDEVEAKTREELEKK-EPLVLINEVIIPALNVVGKDYETGKIFLPQLIQSAETTKKAFEVVKQCFTADA-GEEKGPVVMATVEGDIHDIGK
NIVKVVLESYGYRIIDLGKDVKIEKVVEAWKKYQPKAIGLSALMTTTVISMEKTIQRLREEDCSCPIWVGGAVLTEDIANSIGADYYAEDAMASVALLEK
LI-
>tr|H1BIG1|H1BIG1_9FIRM Putative uncharacterized protein OX=457402 OS=Eubacterium sp. 3_1_31. GN=HMPREF0984_00168 PE=4 SV=1
-MKDKAMI-----TLLDGAMGTMLQEKGLTPGELPEVFGYHHGDIVTSIHKAYVESGADIIYANTFQANRKKLKKGFSVQKIITSAIQQAKKAANV--RV
ALDIGPIGELLEPNGYLTFDEAYDIFKEMVMAGQQAGADLIVFETMSDLMEVKAAILAAKENSNLPIFVTMSFEDHRTFTGCCAASFALLAERLRVDAVG
VNCSLGPDELLPIVEEMAAYTNLPLIVKANAGLPDP-LTN--TYAMQAHEFANSLQRFTHLPIRYIGGCCGTTPAFIAELKQHATGTMVA---K--KIPS
CVCTPTKCVTMD---GVRVIGERINPTGNKRMKQALLDHDLDEIAAIAMEQIEAGAEVLDVNVGLPGIDEKQMMVEVIRHLQTLVDVPLQIDSTDPAVIE
AALRIYNGIAIVNSVNGEISSMQQILPLIERYGANVVGLTLDEQGIANDASKRYQIAKRILTTAQQYHIEKERVFIDCLTLTVSAQQKSAIETLKTLHMV
KEKLQVPTVLGVSNISFGLPRRLLLNQSFLTMALSAGLNMPIINPNHAAMMEAVYSFRVLHGLDVDAQAYIERFAEQKDG-----EQNKGNE--K-AGI-
IDMAIQKGLKEETRALCKKLLEKE-TPLTIVDAYLIPALDKVGNLYENKQLYLPQLINAASASQAAFDEIRQQLQRQGTTITKGKILLATVRGDVHDIGK
NIVKVVLENYGYQVFDLGKDVPVDIIVKTAVEKQIPLIGLSALMTTTLAAMEETIQALHACKHPCKIMIGGAVVSQEYADKVQADYYAKDAKASADIAKE
VFG
>tr|D1PMD8|D1PMD8_9FIRM Putative 5-methyltetrahydrofolate--homocysteine methyltransferase OX=411471 OS=Subdoligranulum variabile DSM 15176. GN= PE=4 SV=1
-------------------MGTQLQKHGLKPGQKPELAALEMPETVTAIHAAYAAAGADLLLANTFGANARKLAEGYSVAEVVKASLHCARTAAEP-ALV
GLDIGPLGELLAPAGTLPFEDAYTAFAEIVQAGVEAGADFVFLETMTDLYELKAAILAAKEHSRLPVFVSMSFERGRTFTGCTVESYGATAAGLGADAIG
INCSLGPAEILPFAQRLCRTVGTPVFVKPNAGLPNP-DGS---YNLDAEEFAREMEAYAAIGVSMVGGCCGTTPEYIARLRDVFSSLTPAQKIP--LRRS
CLCTPVRFVEVD---GITVVGERINPTGKKRLQQALREGDSAYPCTQAVAQAEAGAEVLDVNAGLPGIDEAATLERLVRDLQAVTDLPLQLDSSNPEALA
RALRVYNGKPIVNSVNGEQKTLEAILPLCKKYGAAVVGLTMDEQGIPSSAEGRFAIAQKIVEAAAAVGIPREDIYIDCLTLTASAQQEGAAQTLAALTRC
KEELGVRTILGVSNISFGLPCRGYLNTTFLTMAMAAGLDLAIMNPNTPEMMAAVRAYRVLTAQDKQSAAYVAAYADQVSK-----NVEAAPA--Q-SSE-
LFDAVRRGLKAEAHEAAEAALAVK-APLEVVNASLIPALDVVGDGFEKGTIFLPQLLQAATAAQAAFEAVKAKIAAQGQTTGKGKIVVATVKGDVHDIGK
NIVRVILENYGYDVLDLGRDVPPERVVEAVRTTGAKLVGLSALMTTTVPNMKATIDALHEANLDCQVWVGGAVLTPGYAKEIGADFYCKDAKASADLAKQ
ILG
>tr|F9MSC5|F9MSC5_9FIRM Homocysteine S-methyltransferase OX=879308 OS=Peptoniphilus sp. oral taxon 375 str. F0436. GN=HMPREF9130_0553 PE=4 SV=1
-M-F----TN-KIILLDGAMGTQIQKRGIHQR--PESINISHGEVIEEIQRAYVQAGSDIIYSNTFGAHGRNYPD--ELRKTIHTGLQIAKRAAGKK--V
AFDMGPLGELLEPMGTMSFQRAYELFEQNIQIALEEGFDLVVIETMSSLLELRAAILAVKAHYDGPLLTTMTFEDGRTFSGVSPQAFAIMADKLGVDALG
VNCSLGPFEIQAILKSINQVTNKPLIVKANAGLPDE--EG--NYHMEDDLFIEGIQGMLDLGVQYIGGCCGTTEKTIQGLAKHFKGKEALLQN---KEKQ
YVASSSRVVTLD---QTRYVGEVINPTGKTRLKESLEKKNMEEVLRLGVLQDQKGADLLDVNVSLPGTDEVYLLRKAALHLQALVDLPLQLDSSNVEALE
AALMVTPGRPVINSVNGTQESLDAVLPLAKKYGAMVVGLALDEDGIPKTSEKRLAIAEKIVKTAESYGLEKRDVLIDPLVLTIASNKDSAKLALETIEKL
TKK-GYLTTMGTSNISFGLPKRSLVTASFLQAALAKGCSMPIVNPLDPRIQEVIHTHRLLMGQDEKAMGYIAFMEDKKEA------SASEEE--E-GDFS
PYQAMRRSQKTELLNYVKGAIQEK-DPMEIISEELIPALDAIGQDYEKKEIYLPQLIGAASAAQEAFLFLRDQLRVKGDG-KGEKILLATVKGDIHDIGK
NIAKVLLENYGYDVYDLGRDVSKEEILQTVEEEDIHLVGLSALMTTTVSSMEETIQLLKEKRPDLKIMVGGAVLTQAYAYEIGAHYYCKDAKEDIEIAKN
VFD
>tr|B5Y6I8|B5Y6I8_COPPD 5-methyltetrahydrofolate S-homocysteine methyltransferase OX=309798 OS=Coprothermobacter proteolyticus (strain ATCC 35245 / DSM 5265 / BT). GN= PE=4 SV=1
-MTFLELLSE-RVLFLDGAYGTEFFKQGYKGA--VELLNIDTPKVVEDLQKAYAEAGADVVLTNTFSANRLKLRSGLYIRKINENAVKIARHAAPG-KLV
LGDMSSTGMFVRPLGDLDFEEAYNVFREQAALLIDAGVDGIIVETMSDLKELKAAILAIRNVTDIPLIAHMTFEDGISVTGTSVEIFATLMNDLDVDVVG
INCTLEPKDMLPVFMRLAEYCHKPLSVEPNAGKPLY-NKGVLTYKSTPEEFAVYMADFVELGANLVGGCCGTGPDHIA-LMSKYVGKQKPR--TV-RN-Q
FLSSRTVIKTVEP---FLVIGERINASGRKKLQKSFQDMDYTEILNLARKQEEEGSAVIDVNLGIEKLLTHEHFKQAVLELDRVSSLPLSLDIQDAAFLE
TAMREYVGRPLINSALAREEHLNSRLALLKKYGGMLIVLTMEKD-IPQTAQERLSVAKKAVEIIKANGVDLKRVFFDPLVLPLGAGSD-YHVTLNTIKLL
T-ESGLQTSIGLSNLSFGLPNRESINAAFLGLSVENGLSAAILNSKEATTMNVLQGCLALKGKQLGTTQNA------I----------D-------DEL-
VNL-IVKGQKDALLEFTKQQLKEH-DPLYVSQHILAEAMQKVGELYAKGVIYLPHLILAAETVQPCFDYLNSLL--GEAQVKLGKVLLATVHGDIHDIGK
NIVATVLRSGGFDVYDVGKDVPAHTILEACQEYKPDIVGLSAMMTTTVSRVKEVVDMLKANNIQAFVIAGGASMNRQLADEFGVE-YAKDAMEALQICKA
FME
>tr|E3PU13|E3PU13_CLOSD Putative 5-methyltetrahydrofolate--homocysteine methyltransferase OX=499177 OS=10654). GN= PE=4 SV=1
--------M---IKIFDGGFGSQLISKSICF-ECPEELNLTQGEVIKQIHKEYADNGADIITTNTFGANPLKLKSDLKVMEINVAGINLAKTTGKE---I
AFSVGPTGEFVKPVGDVSFEEMYEIFYRQLEAITISQPDYVIFETFSDIGELRAGIIALKKHIKIPILASMTYDI-YTLTGVSPAAQGVILDALGVDAIG
INCSKGPKDILELLVEIEKYTSVKLIAQPNAGMPEI-VGEDVVYSMSASEFANQMKPYFELNMGYIGSCCGSTPEFTKELRRLVDSIEVKNKEN--KAHG
YLASKGKVVSSE---AFILIGEAINPHARKAVKLYMEEFDIKGLTSVISEQCLKGADVIDINVNAEGADKKALARELVISGQLNSDFVLCIDSKEPEIIE
EALKNYAGKALINSVALDEKELSEILPLAKKYGASVIGLCIENEILPTTIAETVEIAEKLQSRLLSEGIRAEDIYIDPLLFTNKTYSISPLDTVEIVRQL
SNK-GIKTSLGLSNVSYGMKNRDRLNQTLLSMLIGSGLSMAIASASSKGIVETIESAQILMGKEKSNKTYI--------E------LE-DI-----DKLT
IEGLIYQLINKEEPSAFDSLLAEK-TEQEVINTMLI-ALDQAGKLYDEKTIFLPDMMQVVEKVQGLFDRLENKA----KS-S-HTLVFGTVYGDIHDIGK
NIVKSVLKPFGYNIIDLGKSVTKEAFVAKAKEVNADIIGISALMTTTMVNLEPTIEYIKSELPNVKIIVGGAVVTEDYARKVGADGYSKDAIKAIGLVKS
LTE
>tr|D3ATI6|D3ATI6_9CLOT Vitamin B12-dependent methionine synthase family protein OX=566550 OS=Clostridium hathewayi DSM 13479. GN=CLOSTHATH_06945 PE=4 SV=1
-T-LMEEIRK-RIVFFDGGTGSLLQANGLKPGELPETWNILHPEIVTKLHYDYLEAGADIVKTNTFGANGLKFNDEYGLDEIVAAAMENAKKAVSK-GYI
ALDIGPTGKLLKPLGDLGFEEAYRLFSDVVAIGAREGADLVLIETMSDSYEVKAAVLAAKEN-NLPVFATMIFDKGKLLTGGTVESTVALLEGLGVDALG
INCGLGPVQMKGILADIMKAASVPVIVNPNAGLPRS-EGGRTFYDIDADEFAGTMREIVEMGACVVGGCCGTTPEHIRKTIALCKDQPARMPEK--KNRT
VISSYAQAVEIDK--NPVLIGERINPTGKSKFKQALRDHNLEYILREGVAQQDNGAHVLDVNVGLPEIDEAAMMEEVVMELQSIIDLPLQIDTSNIQAME
RALRVYNGKPLINSVNGKQEVMEAVFPLVKRYGGVVVALALDEDGIPETADGRLKVAEKIYAKASEYGIERKDIVIDALCMTVSSDSRGAITTLETVRRV
RDELGGKTILGVSNISFGLPQREIVNAAFFTMALQNGLNAAIINPNSEAMMRSYYSFRVLADLDPQCSEYISVYSGQVAT------LGQTVR--QGGSAS
LAESIERGLKESAHQAVTELLKTL-EPLVIINEEMIPALDRVGKGFEKGTVFLPQLLMSAEAAKAAFEVIKEQLAKSGREEKKGKIILATVKGDIHDIGK
NIVKVLL---------------------------------------------------------------------------------------------
---
>tr|H7ELC2|H7ELC2_9SPIO Cobalamin B12-binding domain protein OX=907348 OS=Treponema saccharophilum DSM 2985. GN=TresaDRAFT_2043 PE=4 SV=1
--FLKERIQAGKPVYFDGGMGTMIQASGVTDYAIPEDLSVTNPDVIKEIHKKYIRAGAHVLTGNTFGINPLKIGDRFSLEEYLKAEFDVMKAAIEP-RYA
AWDSGQIGRLLEPMGDMTFDEAYEAYKIAATTAEKYGAELAILETMSDLHELKAAILAVKENTKLPIVATTTFQNLRTLTGADVLTCVTYLEALRVDVLG
FNCGGSLPDGEELTRQFCRYSHTPVLVQPNAGIPTV-VNGKAVFPARAGEFAQSQLRNRFSGALLLGGCCGTTPDHISAMIGAVESGKASGKRA--EFKT
FICSYNSTVQIGGKAGPQIVGERINPTGKKKVKAALQAHDMNFVLDEAESQINAGAQILDVNVGLPGIDEAQTMVDAVKTIQAAFNVPLQLDSSEAPVLE
KGLRYYNGKPLVNSVNGKREVMDKVFPLVAHYGGAVVALCIDEDGIAPTAEGRCAVARKIIAEAAKYGIPVRDIVIDTLTLTVSSQQKEALETCRAIEIL
KKEFGLQFILGVSNISFGLPRRDIVNSRFFMAALYSGLTACIINPLSEPMMETYHGYRALAGFDENCLGYIEKYTGISAEQ----ARSSAVLP-ADLTE-
LIDTICKGFKDASPDATRKLLDGK-KPVEIIDRCIVPALDLVGKDFESGRKFLPQLLLSADTVSAAFAVIKETLASGAAAEEKGKIVIATVHGDIHDIGK
NIVKAMLENYGYTVIDLGKNVPAETVVKTVVENEIRLVGLSALMTTTVASMEETIKLLREETADVKIIAGGAVLTADYAAKIGADYFGKDAMATVAVAKE
VFG
>tr|K0JL67|K0JL67_BRAPL 5-methyltetrahydrofolate-homocysteine methyltransferase OX=1161918 OS=Brachyspira pilosicoli WesB. GN= PE=3 SV=1
--RL-E-I-E--YLIIDGATGTELQKKE-----CNEILNITAPHIMKEIH-DY-NANANITKTNSFGAI-------------G----------K---IFI
A----P-GVKLPSLGQIGFDEMYSGYTLAARGL-----DIILLETAQDVLQLKAAILAVNDT-DIPIMVSVTIEEGTMLLGTDIETAYTILSNLDIFSIG
MNC-TGP-M--QHIKKLSEISCLPISIHSNAGLPEN-RDGKAYYS----EFAEINSEFF-LG---IGGCCG-TP-------------------------A
-IASLFNSVSIKQEPAPLMIGERSNATGSKIFRELMIAGDMDGMLDVGIKQVKSGSHAIDVNAAWAGRDEIEDITKIISAYVKQISLPLVIDAIKPDVIE
AALKVYGGKPIINSANMEEEKFDAICLLAKRYGASIMLLTIDEKAMALTCEDKLRMCERMYRAV-VHKILPHD---DPLTFTLASGDEN-VETLNAIKEL
SKRYESSISLGVSNISFG------------YE-INHGLSAAIVNVA-----------------------------------------------------A
IRDAMLDGEWKDMQGLLNEVKENS-EEFAIIDEILLP---DIGVKFGEGSIQLPFVLGSAEVMKKSVDFLSEFLE-KKKQEKTAKIILGTVAGDVHDVGK
NLVEIIIKNNGFETVNLGTKVPIEK----YHEHNADCIGMSGLLVKSTEVMKDNLAYIRDKGLKI--LLG---------------FYCKDGFDDIVAIKE
IIA
>tr|E2UZU2|E2UZU2_MYCTU Methionine synthase OX=675518 OS=Mycobacterium tuberculosis SUMu007. GN=TMGG_00680 PE=3 SV=1
--DL-D-L-Q--VMVGDGAMGTQLQAAD-----CNEILNETRPDVLETIH-NY-EAGADAVETNTFGCN-------------S----------Q---RYV
L----P-GTKLPTLGHTEYAVIRDAYTEAALGM-----DAILVETCQDLLQLKAAVLGSRRA-HIPVFAHVTVETGTMLLGSEIGAALTAVEPLGVDMIG
LNC-TGP-E--EHLRHLSRHARIPVSVMPNAGLPVL-GAKGAEYP----ELAEALAGFI-EG---VGGCCG-TP-------------------------S
-VSSLYTAIPFAQDASVLVIGERTNANGSKGFREAMIAEDYQKCLDIAKDQTRDGAHLLDLCVDYVGRDGVADMKALASRLATSSTLPIMLDSTETAVLQ
AGLEHLGGRCAINSVNYEESRFAKTMALVAEHGAAVVALTIDEEGQARTAQKKVEIAERLIDIT-NWGVDESS---DTLTFTIATGQEE-IETIEAIREL
KKRHDVQTTLGLSNISFG------------HE-QEAGLDSAIVHAS-----------------------------------------------------R
LAQRIVDGERNGLDADLDEAMTQK-PPLQIINEHLLA---TVGELFGSGQMQLPFVLQSAEVMKAAVAALGRRFG-QGTHRAQGRRARHRQEPGRHHLEQ
QRLRSG--QHRHQAAN--RHHPRSR----QERRRGRHVGPAGEVDRGDEGK-----PRGDEHPGS--KVP---------------ALRARRFRGPEVHHE
RQA
>tr|F4LNB4|F4LNB4_TREBD Methionine synthase OX=906968 OS=Treponema brennaborense (strain DSM 12168 / CIP 105900 / DD5/3). GN= PE=4 SV=1
--DI-RNLLGKQVLFFDGGTGSVLQAQGLKPGELPETWNLSEREKIVALHYGYYRAGCNIVKTNTFGANRLKFSAG--LESVVLAALENAAEARLP-HFI
ALDVGPAGKLLEPLGDLPFSGAVELFSDTIRAARREAVDLILIETMNDCYEAKAAVVAAKETCRLPIIVTTVYDSAKLLTGADPETMTAVLEGLGVDAFG
MNCSLGPHQMQPILDRLSAAASIPLAVNPNAGLPRS-ENGRTVYDVTPAEFARVTAGFVDRGAALVGGCCGTTSEHICRLVNACAGKPCPVRRD--TGVT
LISSYTKTVAF--GKKPILVGERINPTGKKRFKQALREHDIQYIIREGLAQEEKGAHVLDVNVGLPEIDETELLVTVVTELQSVTDLPLQLDTSDPAAME
AALRVYNGKALVNSVNGKREVMDAVFPLVKKYGGAVVALMLDEDGIPETAEGRLRIVRKIYAAAAEYGIARKDIVIDPLAMAVSSDPGAAAVTLETLRAV
RDEFGGRSILGVSNVSFGLPQRELITASFFTMAMQNGLSAAIMNPNSAEMMKAYACFCALSGYDPHCSDYIAFAESPPLSA----GGAPATAA-GSGSVT
LEYAVIRGLKEDAAARTRTLLGTT-EALDIINNHLIPALDVVGKGFEAKKVYLPQLLMSAEAAKAAFSVIKETLAAGKTDESKGTVVLATVKGDIHDIGK
NIVKVLLENYGFTVVDLGKDVSPERIAEICAEKRVRLAGLSALMTTTVPAMEATITLLRARAPWCKVCVGGAVLTPEYADMIGADFYGKDALETVKYAQS
VFS
>tr|F2NW07|F2NW07_TRES6 Methionine synthase OX=869209 OS=Treponema succinifaciens (strain ATCC 33096 / DSM 2489 / 6091). GN= PE=4 SV=1
--FLFNKIQKHEPVFFDGGMGTMIQKISGLSYSIPEDLNFYNPEAIKDIHKKYILAGSNICTTNTFGANPIKLENSHSAQEFIEKGIALVKGAIENICFT
AWDSGQIGKLLEPNGPLTFDEAYNSYKAAAIAAEKSGADLAIIETMSDLYEVKAAVLAIKENTNLPVIATMTFQNCRTLTGADVLTCVTYLESLHVDVLG
FNCGGSLEEDIELANQFCKYSHIPILSQPNAGLPEV-INGKDVFKVTPEEFTNAQEKILESGVSIFGGCCGTTPDHIKTMAEKLSEKKLKAKKE--KFQS
FICSYNKTVQAGGAAGPVIIGERINPTGKKKCKEALQNNDMQFIIDEADSQINSGAHILDVNVGLPGINEKEMMLQAVKSVQKIFNTPLQLDSSESDVLE
YALRYYNGKALVNSVNGKQEVMDKVFPLIKHYGGAVVALCIDEDGISQTAEGRVKVAEKIIQEAAKYGIPIRDIFIDTLTLTVSSEQKTSLETVKAIRIL
KEKFGIQFVLGVSNISFGLPRRDIINSRFFMLALEAGLSAAIINPASIPMMDTYRAYRALGCFDENCLDYIQTYTGKARQK----ILSTETIG-AEKNT-
LIQIIEKGFKDKAADATARLLEKN-APVKIIDNCIVPALDNVGKDFETGKKFLPQLLLSAETVGNSFLKIKETLAAGKEQEEKGTIAIATVFGDIHDIGK
NIVKAMLENYGYKVIDLGKNVPAETVVKTVIENKIQLVGLSALMTTTVANMEETINQLHKALKECKIVVGGAVLTPDYAKKIGADFYAKDAMETVSAAKE
VFG
>tr|A4E8K1|A4E8K1_9ACTN Putative 5-methyltetrahydrofolate--homocysteine methyltransferase OX=411903 OS=Collinsella aerofaciens ATCC 25986. GN= PE=4 SV=1
--RLRAAIEGTGHLLFDGGMGTMLQAAGMKAGALPELLNFEEPQVITDIQRQYVEAGCDVITANTFGANAHKLDGA--VADVFAAAVTCARAA-GA-HYV
AGDIGPIGALLRPLGTLSFDEAYDLFAEEVRAGVAAGVDLFIIETMTDLAEIKAAVLACRENSDLPVFATMTFEDGRTFLGTSPEVAAITLDAIGADVLG
INCSQGPAELRGLAARMLTVTDKPVMVQANAGLPHV-DDGNTVFDIQAPEYAEAVAGMIADGVSVVGGCCGTTPAHMAALRTLIDNHTPSPRHR--KPSM
SVTSAQTVVDLCDGHKIAVIGERINPTGKKRLQQALRDGDLDYVVSQGISQQEQGADILDVNVGLPEIDEVKIIQQATEQLQGSTLLPLQIDSTDPAAVE
AAVRRYAGKPIINSVNGKQQIMDEIFPLVAHYGTNVVGLTLDEGGIPDTAEARFAIAEHIVAEAARYGIGPDRILIDCLVMTASTNQRQAEQILRAMSLC
KERLGVKCALGVSNISFGLPARPLLGSVFLAAAFGAGLDAPIMNPGSKRFMDTVYSYRVLSVEDEGSTGYIERYAGIAANP----AAAAGTAG-TDDP--
IRRMVVSGRKGEIAAETERLLADH-DAMDLINNHFIPALDEVGVLFDQGKFFLPQLMASAEAARVGFDTIKRLMP-AGEIADKGKICVATVKGDIHDIGK
NIVKMLLDNYGYTVFDLGRDVDPQEVLKTVKERDIKLVGLSALMTTTVVAMEETIKLLHAEVPGVKIIVGGAVLTPEYAKQIGADYYAKDAAESARIAEE
VFG
>tr|B6GAW1|B6GAW1_9ACTN Putative 5-methyltetrahydrofolate--homocysteine methyltransferase OX=445975 OS=Collinsella stercoris DSM 13279. GN= PE=4 SV=1
--TLQRALAGTGHLLFDGGMGTMLQARGLAAGELPELLCLTHPEQITAIHQAYVQAGSDVITTNTFGANRLKLAGA--VRDVFRAAVACARQS-GA-RLV
AADIGPIGALLRPLGTLSFDEAYDLFAEQAHAAQDAGADLFIIETMTDLLEIKAAVLACREQTDLPIFATMTFEDGRTFLGTPPEVAAVTLDALGVDALG
INCSQGPAELRPLARRMLAVTEKPVIVQANAGLPHV-EDGCTVFDIEPEAYAQAVAGMVEDGVGILGGCCGTDPRHVERMAELLRDHAPAPRTI--EAAF
TVTSAQRLVSLCDASRIAVIGERINPTGKRLLKEALRSGDYDYVVSQGIAQQEEGADILDVNVGLPDIDEVTAIQIAGERLSGAVTLPLQFDSTVPTALE
AAVRRYAGKPIINSVNGKREVLDEILPIAARYGANVIGLTLDEEGIPTTAEGRFAIAERIVHAAAEHGIPATRILIDCLAMTASTDQRQAGETLRAIQMV
KRQLGVKCTLGVSNISFGLPQRPLLNSTYLAAALGAGLDAPILNPGSERYMDVVRSYRVLNGEDSGAAGYIERYATVPAAP----DAGTGQTG-AAGPSG
IEHFVLTGRKGEAARATRELLSTI-DPLELIDGHIIPALDEVGARFDRGTLFLPQLMASAEAARASFDVIKEHMP-ASDGLSKGTICVATVKGDIHDIGK
NIVKMLLDNYGYHVIDLGRDVDPHVILKTVQERHIRLVGLSALMTTTVANMAQTIELLHREAPGTLVMVGGAVLTPEYAQQIGADFYAKDAAESARIAAR
VFG
>tr|F0S0B5|F0S0B5_DESTD Methionine synthase OX=868864 OS=Desulfurobacterium thermolithotrophum (strain DSM 11699 / BSA). GN= PE=4 SV=1
--MKENPFRDSKIWVLDGGMGTMLMRKGVDVNYAPELLNMEKPEILKEIHREYIEAGADIIETNTFGSNRIKLSHGNRVKELTAAGVRIAKEAAKDKALV
ALSVGPTGVFVEPVGDYTFDELVDVFKEQIEAGAEAGADLVLIETMSDTKEAKAAVVAAQEVCDLPIMVSMTYQDGRTLLGTPPEVSAAIFEGFGVAAIG
ANCSLGPESFVDLIKRMANITDTPIIIYANAGLPVL-KDGKTYYPEPPETFEKYAPLFVEAGANIIGGCCGTTPEHIKAIKEAVKTLKPIKKNP--TKGL
KVASRTELVIIGTNHPTRIIGERINPTGKKKLQEALKKKDFSLVKEEAKKQVEEGADILDVNVGVPGINEAQAMEKAVRTVIETVNVPIMIDSKDPEAVE
RALKMCDGKPIVNSCSGEEKDIKNILPLVKKYGANILVLGIDDEGLKEKAEDRAAIIDKLVEECQKLEIPKDFIIADVLNLAASAMQEATRETLKAIRIV
KERHGIATTLGVSNVSFGLPGRSLLNSSFMAMAIEAGLDSGIVNPADSRMVETIYASDVLVGKDKGATRYVEKFQNKPKTE----DKEEDESI-PPGILK
IFKKVLEGDKEGIIKPTEEALKEF-EPMEISDKALIPALDVVGQRFEKGEIFLPQMLRSAQAVQSAFEIIKREVKKGGNVKVDGKIVMATVYGDVHEIGK
NIVITMLENSGFEVIDLGTNVPPEKIVEVAKKEKADVVGLSALMTTTLPSMEETIKKLREAGLDVPVIVGGAVVTPEYAKEIGGH-YSEDAQEAVKIVRK
ILN
>tr|E8T5Z7|E8T5Z7_THEA1 Homocysteine S-methyltransferase OX=648996 OS=Thermovibrio ammonificans (strain DSM 15698 / JCM 12110 / HB-1). GN= PE=4 SV=1
--MPTNPFKQEKIWVLDGGMGTMLMAKGVDVNFAPELLNVEKPEVLKEIHSEYVEAGADIIETNTFGSNRIKLSHGNRVKELTAAGVKLAKEAARGRALV
ALSVGPTGVFAEPVGDYTFDELVDVFKEQIEAGAEAGADLVLIETMSDIKEAKAAVFAAREVCDLPVLVSMTYQDGRTLLGTPPEVAAAVFEGFNVAAVG
ANCSLGPESFVEIIKRTASVTTTPIIVYANAGLPVL-ENGKTVYPEPPETFEKYAVEFVKAGANIIGGCCGTTPDHIRAIKRAVEGLKPVERNP--VKGV
KVASRTKLVLIGTGHPTRIIGERINPTGKKKLQEALKAKDFSLVKQEAKKQVEEGADLLDVNVGVPGADEPSLMREAVKTVMEAVDVPLVIDTKDPKAVE
EALKMCDGRPVVNSVSGEKKDVEQILPVAAKYGANVLLLAIDDEGLKEKAQERVEIIERLLKECEKVGVDRSSTVADVLNLAVSAMPDSTVETLKAIRLV
KERFGIATTLGVSNVSFGLPSRSLINSAFMAMAIYAGLDSGIVNPGDSRMVETIFASDVLVGKDRGAERFVSRFQNSPKGE----DAESDSEA-PAGILT
IFKKVLEGDREGIVGPTEEALKEF-DPVEVSDRALIPALDVVGKRFEKGEIFLPQMLRSAQAVQAAFEVLKREMKKGGNLKLGGKIVMATVHGDVHEIGK
NIVITMLENSGFDVIDLGTNVPPAEVVRAAKEHNADIVGLSALMTTTLPAMEETIKALRDAGVEVPVIVGGAVVTPEYAESIGGI-YGGDAQEAVKIVKK
LLK
>tr|I0X8T3|I0X8T3_9SPIO Homocysteine S-methyltransferase OX=1124982 OS=Treponema sp. JC4. GN=MSI_14350 PE=4 SV=1
--VLAKDIFKKDFVFIDGGCGSILQAQGLQPGELPETWNILHPEIIQKMHRDYLLAGANILTSNTFGANINKFQ-GKFLDAVIGAAIKNARQAIQP-HFV
ALDIGPLGKLLKPLGDLDFEDAVKIFSYTVKIGAKHGADLVLIETMNDLHEAKAALLAAKENCELPVLITTAYDSEKLLTGADPMTVVATMEGLGADAVG
VNCSLGPDQMFGIVEQLARYASVPVVVSPNAGLPRS-EGGKTVYDVAPADFAASMEKIADLGATMLGGCCGTTPAHIKAMSDAVRTHKAHEVTP--KNDT
IITSYTHSVIF--DKKPVLIGERINPTGKKKFKEALRNRDMDYILGEALTQKEKKADVLDVNVGLPEIDEPQMMIDVVKELQAVIDLPLQIDTTNPVAME
KALRIYNGKPMINSVNGKEEIMKEIFPLAKKYGGLIVALTIDESGIPETAQGRVEIARKIYARAAEYGIKPKDIIIDPLAMSISSDPQSAITTLDALRLI
KEQLNGKTSLGVSNISFGLPQRDFVNASFFTMAMHNGLNAGIMNPGSLEMMKAYYTYCALLAVDQNCANYIDFATNAPVAA----AGSSAAAV-SAGGSE
LIEAIKRGLKDRAAALTGEYLKSK-DALQIIDGELIPALDIVGKGFEKKTVFLPQLLMAAEAASAAFGVIKQTLAAGGDQQKKGKIVLATVKGDIHDIGK
NIVKVLLENYAYDVIDLGKDVDPQLIVETVQRENIRLVGLSALMTTTVPAMEETIKLLREAGSPAKVVVGGAVMTQNYADMIGADKYCHDAMETVRYAEE
IFA
>tr|G1WIU6|G1WIU6_9ACTN Putative uncharacterized protein OX=742742 OS=Collinsella tanakaei YIT 12063. GN=HMPREF9452_01259 PE=4 SV=1
--NLRAALEGRRHLLFDGGMGTMLQAAGLKAGALPELLCLTNPDAITRVHAAYVAGGSEVVTTNTFGANALKLHGA--VEEVFNAAVACARAA-GA-RYV
AGDIGPLGTLLRPLGTMGFDEAYDYFAQEARAAQAAGCDLIIIETMTDLAEIKAAVLAAKENCDLPIFATMTFEDGRTFLGTSPDIAAITLDALGADVVG
INCSLGPAELRPFARTMLAVTAKPVMVQANAGLPHV-EDGCTVFDIDPQSYAAAVANMVEDGVGIIGGCCGTNPDYIRLLADIIADRAPQQRPA--PASF
TVTGAQRLVELQDSHRVAVIGERINPTGKKRLQAALREGNLDYVVGQGISQQEQGADVLDVNVGLPGIDEPRMIARAVEALQGATLLPLQIDSTNADAIE
AGVRAYAGKPIINSVNGKQEVLDAVLPIAAHYGCNVIGLTLDEDGIPATASERVAIARRIIDEAARYGISRERILIDCLVMTASTNQAQVTEILRAVTLC
RQELGVHCTLGVSNVSFGLPARELLNATFLAAAFGAGLDAPIMNPGSQRYMDAVYSYRVLNAEDLGSAQFIECYAGVPVNV----ASTTSPNT-APSPAG
LHHLVLSGRKADVPALVRDLLAEH-DAMDVIDRMLIPALDEVGDKFDRGEFFLPQLMASAEAARAGFDTIRDLMP-AGNVADKGKIALATVKGDIHDIGK
NIVKMLLENYGYRVYDLGRDVDPQVVLDAVRQHDIPLVGLSALMTTTVTNMEETIALLRREAPGVRVFVGGAVLTPEYARQIGADFYAKDAAESARIAER
VFA
>tr|K0YME9|K0YME9_9ACTN Uncharacterized protein OX=742818 OS=Slackia piriformis YIT 12062. GN=HMPREF9451_00215 PE=4 SV=1
--YLARVIAGEEYLVFDGAMGTMLQAAGLEAGELPELLCLNSPDEVIAIHRQYVEAGSLAVTTNTFGANARKLGDA--VREIFAAAVACVRNA-GA-RYV
VADIGPTGALLAPLGTMSFDEAYDLFAEQVRAAAEAGADIILIETMADLLEMKAAVLAAKECSDLPVFATMTFGDGRTFLGTSPRIAALTLSALGVQALG
MNCSLGPDDLRPLVDEMLEVATCPVMVQANAGLPHV-EDGKTVFSVDPDSYAKSVAGMVEAGVRIVGGCCGTNPAYIANLADIVCGKQPTRSFA--EPVC
SVTSAQEAVVL-KGRHVATIGERINPTGKKRLKEALRTGDFDYIINEAIAQTEAGADILDVNAGLPEIDEAAVLVDLVGKIQGVTGLPLQVDSSDPEAVE
AAVRVYAGKPIINSVNGKAESLAAVLPIAKHYGCAVVGLTLDEGGIPPTAEERFAIAERIVRAAEAAGIPRQDVFIDCLVMAASTNQSEVVEILRAITMV
KERLGVRTVLGVSNVSFGLPLREVVNATFLAAAFSAGLDLPILNPLSDRYREIVDSWRVLCGQDVSAARYIEEYANMASAS----ALAQVAVS-SEAPD-
LRHCVITGRRAQAADIVRSMLEKV-EPMAVINDHLIPALDEVGERFEKGTFFLPQLMSSAEAAKAGFDVIKELAS-SASVADKGKVAVATVKGDIHDIGK
NIVKMLLENYGYTVFDLGRDVDPQAVVDCVKKHGIKLVGLSALMTTTVRGMEETIALLREQAPDTKVFVGGAVLTPEYAKMVGADYYAKDASESARICAE
VLG
>tr|G7V6S1|G7V6S1_THELD Homocysteine S-methyltransferase OX=580340 OS=Thermovirga lienii (strain ATCC BAA-1197 / DSM 17291 / Cas60314). GN= PE=4 SV=1
--KFWQWMEAKRVILMDGGMGTLLAEKGWKPPMLPEEMNVYSPDVVASIHEAYLASGADIIETNSFGGSTRKLAHGGKARDINKEAARIAKGCAGDKALV
AGSVGPLGELLEPFGSLSFEEAYEAFYEQIAGLAEGGADFILIETMMDIREAKAAVAAAKDAAGLAFVVSFTFDHGKTVTGTPPEVAAAWAYAVGAAGVG
ANCGVGPGEYVETVKKLWEYSRLPVFVYANAGLPGD-END-------PRAFAEKSKELALAGASVIGGCCGTTPEHKEALAGVLSLPPSSRKET--F---
-LASRSKLVAAGCGGPLLVVGERINVSRKSALKEQVANGDFTLLKEEAKLQEQAGAEVIDVNVGLPGVDQVALMSEAISVVEATVTSPVSIDSDKIEVLE
AGLKRASGVPLINSVTAKQGHLEKGLELASRYGAVLTVLPMDEKGLPHTIEERRAVIDSIVERARKTGFPMENLIIDGLTLAVGADEKAPRVTLQALEYI
S-QLGCLSILGVSNVSHGLPSRHLVNRTFLAMAMASGLGAAIIDPTAPGIFETILASNLLRGSDPKALNYIQAQDKVEPGR----DSAPKKEE-RKKEIP
LMEAIIEGDEKAAQLHVRDLIDEK-GPMDVISCGIIPALEEVGKLYEVGEFFLPQLLASAQAAQVSCDFARERMEPD-RGENKATVVLATVEGDLHDLGK
NIVGTVLRSYGYQVIDLGRNVPAQKILEAASESNAHIVGLSALMTTTMEEMARTVKLLKEKLPHLPVIVGGASVNESFAKKIGSDGTAPDAIGAVRLVSR
LTE
>tr|D1B7X8|D1B7X8_THEAS Homocysteine S-methyltransferase OX=525903 OS=Su883) (Selenomonas acidaminovorans). GN= PE=4 SV=1
--RVRSLLGEVSPLVMDGGMGTQLAERGWHPPMLPEEMCLHMPQAVREVHESYVESGAAVLETNSFGGSVRKLSMGHLAEELALRSAQIARQAAGD-ALV
AGSVGPTGEMLAPLGEMSFEEAVKSFEPQVRGLIRGGADLILIETMLDLKEAAAAVEAVKRVDLFPFVVSFTFDDGRTVTGTTPEAAACWAQAVGALGVG
ANCGLGPRGYVPVVRRLAEASPLPVWVYPNAGVPSA-GDG-------PDEFVGECEELLKAGASVIGGCCGTTPDHVRALAALARGRRVTRLHC--DGGV
RLSSRSRVISAGAGLPLAMIGERINVSRKSPLREQVGEYRYGEVKREAKAQTVAGAAVIDVNVGLPQIDQVRAIREAIWAVESVTHLPISIDSDAPAVLE
AGLAEAVGVPLMNSVTAKEESLELGIRLALRYGAVLAVLLIDQRGILEDGLERARIAQRVLDVASSRGLGPNRIVFDPLTLTLGASQSNGLETLRAVEAV
S-RMGGHTMLGISNVSHGLPARGLLNRTFLAMAMERGLDMVICNPLDRELLGVVRAADALRGRDRGLGAFMAFGPSREPER----GAVQAAEA-SAGEVE
LSRRVMEGDRDGALAEALTVMAQE-GPMEVISGHLIPALDEVGRRYETGEFFLPQLMEAAEAASAVCRLAEEELLRG-RSANRGTVVLATVEGDLHDLGK
NLVGTVLKSHGYRVVDLGKDVKAEVILEAAQREGAQVVGLSALMTSTVPRMREFIEEARRRGAGFKVIVGGAAVSPAYARSIGADGMSYDAVGAARLVER
LLS
>tr|D3L3E4|D3L3E4_9BACT Vitamin B12-dependent methionine synthase family protein OX=592015 OS=Anaerobaculum hydrogeniformans ATCC BAA-1850. GN=HMPREF1705_01562 PE=4 SV=1
--KFVDLITSLRVLVLDGGMGTMLSEKGWRPPMLPEEMNLIAPDVVLDIHKEYLRSGASVVETNSFGASPIKLSYGEKARRINEEAARIARRAAEGWAYV
AGSMGPLGELIRPLGNLSFEEAYEAYKEQAIGLRDGGVDFFLIETQMDIKEAKAAVLAIKDVAHIPFVVSFTFENGRTITGSPPEVVAHWARMIGACAVG
VNCGFGPDLAREIVKKLYLNAGIPIFAYPNAGTPGK-EDD-------PREFAEEGRELIRAGASVVGGCCGTTPEHLKGVASQEKPLRPRKVEK--A---
ALASRSRLVFAGAGEPIVVVGERINVSRKSPIRDEVAQYKWDALSEEARRQSSSGSQVIDVNISLPGIDRKRAIREAVEAVESACTLPISIDADEADVLE
EGLIHVAGIPLINSVTAEREKLIKGIELAKRYGACLVVLAIDEDGISETVEGRIKAVEKVCALADEMSFSKSRLFVDPLTMSVAADGRAGVVTLEALRAF
K-KLDLFTIMGVSNVSHGLPNRPLLNNAFLTMAAGAGLDSVIANPLDESFASLMMACNLLVGRDKGASGYITWARSKSEEK----DTSSKKEG-ASSPIQ
MKGMIVQGDRGGVLAVARRFLSEG-GPLALINDVVLPALEEVGRLYECGDYFLPQLISSAEAAQGVCDLVEQAVLSGGTLKDRGCILMATVAGDIHDIGK
NIVSMVLKSHGYRVIDLGKDVALEKILEEARRGEAQIVGLSALMTTTMSEMERVTRKIKEENLSVKVIIGGAAVSQNYADHIGADGYAPDALSAVRLVEK
LL-
>tr|B6AR37|B6AR37_9BACT 5-methyltetrahydrofolate--homocysteine methyltransferase OX=419541 OS=Leptospirillum sp. Group II '5-way CG'. GN=CGL2_11238056 PE=4 SV=1
---MRPLLERLNILLLDGSMGALLQSRGLPPGYAPDLWNLERPQDIQQVHSEYVEAGSDIILTNTFGSSRLRLREDGQIREINEAGVEMARRAAKGKAYV
AGDIGPSGTTIAPFGDLPFDDAIGIFYEQARILLGAGVDLIAIETMFDIQEMRAALIGVREVGRVPVMALMTFNDGITDSGSDPETAASVLEGFGVDILG
LNCSVGPEAMVPVVRRLGQTTSTFIAVEPNAGLPVH-RDGHTVYPANAEEVARFAPQFVEAGANIIGGCCGTTPEYVRLLSRMLKGISPISRPA--PTLM
KISSRTHMTLVGPGVPFLIVGEKINPTGKKKFSEAIAAGQTDLIVAEARKEMEAGAGALDVNVGVPLVNEAEMMAKALTAIQNVVQLPIVIDSSYASALE
AGLKVYPGRALVNSVNAEEERLEEVLPIIKKYGAAVIGL-VSGDDIPEKATDRLKNAEKILRRAHDLGLSPRDLIFDTLALTVSAVQEASRQTLETIRLI
RQELGLPTILGLSNVSFGLPARKLVHDNFLAMAIGAGLDAAICDPYDTVLHQTVAAASVFAGRDPDCRIYIDKSAQSPDAK----DANPQKNQ-PQKPLA
IRKAIEEGERESISGLVQKALAEG-EPFAIFLDHMTPAIRHLGDLFGQRIKFIPHLIAGADTMKKGVEVLQPYLESG-PVEKKGTIVFATVKGDIHDIGK
NICILMLRNFGFNVIDLGRNVPLETILDAAREHKAQIVALSALMTTTMMQMKLAIDTIQERDLPYKVMIGGAVVTPRFAEEIRSDGYGKDVGAIVPLAEQ
LIQ
>tr|C9M596|C9M596_9BACT Vitamin B12-dependent methionine synthase family protein OX=645512 OS=Jonquetella anthropi E3_33 E1. GN=GCWU000246_00352 PE=4 SV=1
--PSRRLTLGRDRIIFDGAMGTALGSRGLRRGSLPEELNLSSPETVAAVHRSFLEAGSDFITTNTFGAFPSRLAHGLSVGPVVRSACQIARREAGG--FV
ALDIGPSGRLMEPLGDATFDEIYQGVCEVLHAGAAY-CDAVLLETFTDLAEIRAAALAVRENCGLPLLATMSFESGRTFSGASAEACSLVLSGLGASAFG
TNCSAGPRALRETVRQICGACPVPVIVQPNAGLPEF-SGSSVVYSAGPDEFQSVMGEFARWGVAVLGGCCGTTPDYIRRLSSLRGDVPPRSVPL--GPA-
-ACSASQVVRF---DMFVPVGERINPTGKPVLADAYASRLPSPLLEDAIKQTQEGAVMLDVNAGVPGVDEAAALSWAVQTLQEGVTCPLQLDSANPKALE
AALRACVGLPMINSASARPESLEPAIRLAKKYGVSILGLPMDETGVPERAADRLAVAARIKERWTAAGLAAEKLLFDPLVMAAAAGPERVSETLNTLSAL
KERLGAKTMAGISNVSFGLPARGAVNRTMLAACLDRGLDAAILNPGDLGMMDTVAVWNLLSGRDADASGYLAYCAA------------ALPVP-EANQD-
LGRAVRLGLVQEARRAAAELCKGV-SAMTVVEEYLVPALDRVGDDYEAGRIFLPGLLKAASAASAAFDEIRQALPAGSGARDKGPIVLATVQGDVHDIGK
NIAGTVLESYGFRVIDLGKNVPAETVVRTVVENRAPLVGLSALMTATVASMEDTVAALRRAAPGVKIIVGGAVLSRVLARSIGADYYAATAMETVRLAEK
AIK
>tr|I4BUC0|I4BUC0_ANAMD Homocysteine S-methyltransferase/B12 binding domain/Pterin binding enzyme OX=891968 OS=Anaerobaculum mobile (strain ATCC BAA-54 / DSM 13181 / NGA). GN= PE=4 SV=1
--GLFGKIFAGKVLILDGAMGTMLSDKGWQPPALPEEMNLTNSDVVADIHRQYLKSGADIVETNSFGSNPIKLSYGGMTQRINEEAARIARRAADEFAYV
AGSMGPLGELIEPLGRLTFDEAYESYKKQALGLISGGVDFFLIETQLDIKEAKAAVLAVKDVAHTPFVVSFTFENGRTVTGSSPDVIAHWARMIGASAVG
LNCGFGPDLAEKVVKDLYDNAGIPVFAYPNAGTPGS-KDE-------PHEFAEKTAALIKAGACVVGGCCGTTPEHLRKMAGGLEPPCPVEIKK--A---
ALASRSRLVLVGDDEPIAVIGERINVSRKSPIREEVARYKLDALSEEARRQAECGASVIDINVSLPNVDRKKAMREAVKAVENACMLPLSLDSDEPEVLE
EGLIHASGIPLINSVTAERQKLTKGIELAKRFGACLVVLAIDEDGIAETPERRLAAVRKACNIADELEFPRNRMLVDPLTMSVAADRSSGIVALEVLRNL
R-KLGLFTVMGISNVSHGLPERSLLNKTFLTMAAGAGLDAVIANPLDDGFTPMMMACNLLAGRDEGALRYISWANSRGKVE----HIARGQED-LLGPIQ
MRRCIVQGDKSGILEKASRFLAEG-GPLGLINDVVLPALEEVGRLYECGEYFLPQLISSAEAAQGVCDLVEKTVLSGGKLKDRGCIIMATVAGDIHDIGK
NIVSMVLKSHGFRVIDLGKDVPLERILQEAKKGEAQIVGLSALMTTTMREMERAAKTIKEENLPVKVIIGGAAVSQGYADAIGADGYAPDALSAVRLVEK
LLT
>tr|H0UR06|H0UR06_9BACT Homocysteine S-methyltransferase OX=926567 OS=Thermanaerovibrio velox DSM 12556. GN=TheveDRAFT_1725 PE=4 SV=1
--RVREFFRGLSPLVLDGGMGTQLAERGWHPPMLPEEMCLHMPQAVLEVHRGYVASGAAVIETNSFGGSVRKLSLGDRAEELARRSAELARRAAGDQVLV
AGSVGPSGDMLKPLGDMSFQEAVMSFEPQVRGLVEGGADLILVETMLDLKEAKAAVEAVKRVRDMPFVVSFTFDDGRTVSGDSPEAAAIWAEAVGAIGVG
ANCGLGPRGYVEVVRRLAGAASLPVWVYPNAGVPSA-GDG-------PQEFAEGCAALLEAGASVIGGCCGTTPEHVKALAAMAANRSLAATDA--AGGL
RLCGRSKVFSFGPGLPLGIIGERINVSRKSPIREQVGLYRYGAVKEEARSQALAGASVIDVNVGLPEIDQVRAMREAVWAVESAAPLPISLDSDDLGVLE
AGLREAAGVPLINSVTAKEEQLRLGMRLAMRYGAALTVLLIDHRGILEDGLERARIAERVLEAAREEGFPGSRIVFDPLTLTLGSGEANGLETLRAVREV
V-ALGGLTSLGISNVSHGLPARGLLNRSFLAMAMGAGLDMVICNPLDRELMGIVKACDALRGRDKGLSCFMAFGADKQPEG----GAVGGSKA-PDGEVP
LAAKVLDGDEEGALGEARRLIDLE-GPLGVISDHLVPALDEVGRRYETGEFFLPQLIEAAQAASAVCALAEEELLRG-SSASRGTVVLATVEGDLHDLGK
NVVATVLKSHGYRVVDLGKDVKAERIVEAALREGAQVVGLSALMTSTVPRMKEVIEETHRRGCGFKVIVGGAAVSPWYARSIGADGMSYDAVGAC-----
---
>tr|B1H0N5|B1H0N5_UNCTG Homocysteine S-methyltransferase OX=471821 OS=Uncultured termite group 1 bacterium phylotype Rs-D17. GN= PE=4 SV=1
--KFLDILKSR-ILIMDGATGTELQKKKYLDGVIPEEINIKFPERIADIYSSYINAGSDIILANTFGANLIRLKQGDKADDIIKSGIDLIREISSD-TIV
AGDISSIGEYIEPLGSLTFDEAYNSFAFQVSLLQKHGADVIVIETMTEIKETKAAILAAKE-NDGAIIVQMTFSDGVTVTGTDLKSFIAMAESLGVDALG
LNCSIGSRDLAELAKVLCVNTNLPISFKPNAGIPVL-INRETCFPETKEEFIEASLKAYSYGVNMFGGCCGTNPEFIKILSGELMNKAPKIRSV--KSKY
FLSTRTKTIDINEAEKPVIIGERINPTNRKKFQEELLKGNLSTVKDEARSQVWSGANLLDVNMGVPGTDEIKLLINAVNQIQETVSVPLCIDSSNSGALE
QAVKNCAGRPLINSVNGEQAKLDVILPIAKRYGAALIALTTDDNGIPATAEKRLKIAAKILNFADRCGLERKNIVFDYLVLSASSSPDQIGETLKAMRES
K-RMECKLVLGVSNVSFGLPSRQTINSTFLKMAVAVGLDFAIANPHENWDIDDPFAKNLLENKDKGAVKYMEVFTSRKQIP----ETE-TEKL-TTDK-Q
LYFAILNGNRDSVDDILSQIIASG-DPFRTVNNNVLKALNVVGEKFASKEYFLPQIIMSAQAAQSAFAIVKATLKK--EASSAGKIIIATVKGDMHDIGK
NIVGAVLESYGFDVIDMGVNVDSQSIIDEAHKINPIAIGLSALMTTTMPEMGMVVKLKNAARVPTKIIVGGAAVTEKFAKEIGADAYARDAMEAAGYVKT
LQK
>tr|E3CXR8|E3CXR8_9BACT Methionine synthase (B12-dependent) OX=584708 OS=Aminomonas paucivorans DSM 12260. GN=Apau_0225 PE=4 SV=1
---MKRLFAGQSPVILDGGMGTQLALAGWRPPLLPEEMVLENPDSVTAIHRAYVEAGARIVETDTFGGSALKLAHGGRTEEINRRAAELARQAVGDRAFV
AGSMGPIGRLVDPLGDLTFDEAVEAFRPQAAGLARGGADFLLVETMLDLKEAQAAAVACREAAGLPFAVSFTFDDGSTVTGTPPEAAAVWAEAVGAFAVG
ANCGVGPEEYVDTVHRLAASTDLPVFVYPNAGVPSS-RDG-------PEAFAGACEALVRAGAAVVGGCCGTTPEHVRRLGGMAIPPSLRRER----GVL
RFASRSRVVEAGQGRPLLLIGERINVSRKSPLREELRVQDYTTVRAEARDQTAAGAGLLDVNVGLPEIDRIRAMGKAIHVAEAASSLPLSVDSDDPTVLE
RGLREAVGVPLLNSVTAKAEALERGIDLAWKYGAVLAVLTIDESGIPERAYDRVAIAQRVLLRASERGLGPERILLDPLTLALGADPRNALATCEALRCI
R-ELGGHTMLGISNISHGLPARGLLNRTFLVMAMEAGLDAVLCNPLDERLLATVAAADALRGRDEGLRRYLAFAPGVPASG----GASRGEPA-KGGEQP
LTRCILEGDPAGAEASARALVDRT-SPLDLVSSWVVPALEEVGRLYECGDTFLPQLLASAQAAGGVCRLAEELLARGVKQEPKGTVVLATVEGDLHDLGK
NVVGMVLASHGYRVVDLGKDVPAERILEAAEAERADVVGLSALMTSTVPQMEAVIRGARERGAAYRIIVGGAAVSPQYAESIGADGTSSDAVGAARLVEQ
LLA
>tr|D1Y627|D1Y627_9BACT Homocysteine S-methyltransferase OX=352165 OS=Pyramidobacter piscolens W5455. GN=HMPREF7215_2692 PE=4 SV=1
-----MMKEFDRVVMFDGAMGTMLQKKGLKLREIPESLNVSRPDLIESIHREYFAAGCDFVQTNTFGANPYKLEGA--TEQVIGAAVKIARRAASG-KGI
LLDVGPSGRAMAPVGDADFDEIYGSVARQVRAGAEL-CDGILLETFTDLLEAKASALAALENSDKPVFLTMSFQDGRTFFGTPVEAMIMTFEGLGLSGLG
VNCSLGPAQLAPIVKKLTAHSRVPVIVQPNAGLPVV-RDGVSGWDVSPGEFANWLGQFVDWGTAFVGGCCGTTPEFLSAANDMIGNRRLRPRKV--APLR
GVCSATRVEPF---DRTVIIGERLNPTGKKRLKQALYEHDFDYVVLEAQKQKEQGAGVLDVNVGLPDVDEPAMLREVVAELQGAVDLPLQLDSANAAALE
AGARRYAGKPLLNSVSGKESSLASVLPVAKKYGACVLGLCLDDGGIPQTAEARFAVAQKILDRAAALGIPKDDVFIDCLTLTASAQQDLALETIKAVRMV
SERLAVKTTLGVSNVSFGLPRRPLINRTMLAAALANGLSAAIVNPGEKSVQETLAAWRVLSAQDRDAKEYIDFCAANPEET----AFAVAAVS-ERGKF-
LGEAVARGLKDEARACAAELVKKQ-PPLEIVEKTLIPALDAVGRDYEAQKIYLPQLIKSADAAKAALEVVKGVLAGGGAPRSGPKVIVATVYGDVHDIGK
NIVKVIMENYNFDVIDLGKDVSSDAIVAAVKKTGAAVVGLSALMTTTVASMKETIAALRRECPEVRVIVGGAVLTPDLARHVGADRYARDAMDTVRAVEE
FLS
>tr|H9UC42|H9UC42_FERPD Homocysteine S-methyltransferase/B12 binding domain/Pterin binding enzyme OX=771875 OS=Fervidobacterium pennivorans (strain DSM 9078 / Ven5). GN= PE=4 SV=1
--KFSELLSQR-VMFLDGAYGTELFKRGYKRE-PIELLNITNAKAVLSLQSDYVCAGVDFLLTNTFSANRHKLMKGEYFKEINQSAVKIAKEATKN-KFV
LGDISSVGEMIEPLGELKSKYVYNIFKEQVEVLVDVGVDGIIIETMSDIKEAKLAYLAARDVAEIPVLVSMTFENGVTVTGTSLEVYVALFNDLDVDAIG
INCTLTPEKMVPLVKKLVALSKKPVFVEPNAGKPLS-ADGKLTYKTTPEEFTIYIEDYVELGANIVGGCCGTGPEHIKYMVQHIGLKRPKARKV--EELN
VVTSRVHMFNV---APFLVVGERINASARKKLHNEIREFNFENVLKLAKSQEQEGAQVIDVNFGIESVLSEEHFSKAIVELDKIVSIPISFDIQYNEFLE
SALMEYPGRPLINSSKATKEELDKKIRLLKRYGGLLIVLAMGKE-IPKTAEERYTLGKMAVEYLESQGIDRSRIFVDPLVLPIGANQDY-NVTLETIKKL
SSD-GIKTMIGLSNFSFGMPNRDELNASFLALAMHSGLSGAILNTSEDATMKILRGMIRILGKES-----------ARISE----EVKS----------E
LVHLLLRGNLNDAEKHVLSFLDTL-TPIEIIQTILAKAMEEIGNLYAENKIYLPHLILAAETSKPIFNKLLSMVA-EKDSARLGRILLATVEGDIHDIGK
KIVATVLESAGFEVIDIGKDVPASVILEKVKELKPDIVGLSAMMTTTVIQVGHVVKTLRDNGIEIPVIAGGASMNGELAKRFGS-YYAKDAQEAVKLCKQ
ILT
>tr|G9PTR9|G9PTR9_9BACT Putative uncharacterized protein OX=457415 OS=Synergistes sp. 3_1_syn1. GN=HMPREF1006_01962 PE=4 SV=1
------MIELDKILLFDGAMGTMLQRRGLELGTVPEALNVTAPEAIESIHREYLAAGADVILANTFGANRFKAEKG--LAKMVAAGVKTARKAIPG-RYA
ALDIGPCGRVLQPAGDLPFDEAVEVFAEVIRAGTEAGADFILLETFTDLYELKAAVIAAKENSPLPVFATMSFENGTTFFGASVESMVMTLEALGVSALG
VNCSLGPRQLVPIVRRILAATRLPVLVQPNAGLPVM-EDGVTRYDITPEEFASSIREFVAEGVRFVGGCCGTTPEYIRLTKSTIAGMAPAAIET--APRY
GICSPSKVVGF---DRVTVIGERLNPTGKKALQAALRAHDMDFVLREAIREEEQGAEVLDVNMGLPDIDEPAMLSEAVREIQAVTDLPLQLDSASPAALE
RAARIYNGKPLLNSVNGKKESLDTVLPIAKKYGCAVLGLTLDEKGIPKDAEARLAIARRIVKAAEAAGLRREDIFIDCLMMTVSAQPDQAHETMKAISLV
KKELGVKTVLGVSNVSFGLPARPIINRTMLAMALASGLDAPIMNPGDAGMTETVAAARVLLEQDADSKEYVEKYGGA----------AAAPVK-DEAPQ-
IGYAISRGLKDEAAKAAAALLAEQ-PPLAVVEKEIIPALDTVGKDYESGRIFLPQLIKSAEAAKAAFEVLRAELIKSGDTQKGKKIVIATVHGDIHDIGK
NIVKVILENYNFDVTDLGKDVPPRQVIAAVKETGAKLVGLSALMTTTVASMRETIELLRRECPGVKVIVGGAVLTEGLAAYAGADRYAKDAMETVRHADS
L--
>tr|H2J4L7|H2J4L7_MARPK Homocysteine S-methyltransferase/B12 binding domain/Pterin binding enzyme OX=443254 OS=Marinitoga piezophila (strain DSM 14283 / JCM 11233 / KA3). GN= PE=4 SV=1
--EFSELLNQR-VLFLDGAYGTEFFKMGI-RGMPIELLNITNPDAVYTLQKAYVNAGVDFLLTNTFSANRLKMQSKENIKDINFHAVKIAKDAAKN-SKI
LGDISSTGILLTPLGELSFDEAYEVFKEQGEILLNAGIDGFIIETMSDLKELKAAFLALRDLDNIPIIAHLTFENGRTVTGTSVEIFATLFNDLDVDVIG
MNCTLTPEEMIKVFQTLSKYSKKPISVEPNAGKPLQ-PDGSVIYNTTPEKFSVYMEDFVHLGANIIGGCCGTGPEHIKLMREFIGKTRVRKRET--IKKQ
FLSSRTILRET---EPFLIIGERINASGKKNFQNAIREYNFDRMVNLATAQEKEGSHVLDINLGIEKLLDKKHFEKSIIILDKIGSIPLSLDIQQPEFME
VALKEYVGRPLINSSTVEKEKLDTAIRWLKRYGGMLILLTMKNK-IPETAQERFEIAMKGIKYLEENGISKDRIFVDPLVLPVGAKKDP-FVTLETIKLL
SEK-GIKTSIGLSNLSFGLPSREGINASFLSLAIHNGLSGAILNSKESSTMNIVFGSLILHGMEV-----------SRDTS----TSTD----------E
LADLILKKKSRELKEKINLLLKDY-TPLQVSQNILAKTMEYIGELYSKGEIYLPQLILAAETVTPIFEYLNNMLK-KEESSSKGTILVATVEGDVHDIGK
KIVATVLKSSGYEVIDIGKDIPGKIILEKVKELKSDLLGLSAMMTTTVGKIKEVKDLLLENGVEIPIIAGGASMNKELASKFGV-FYAKNANEALKYAKR
FIN
>tr|A6LKZ2|A6LKZ2_THEM4 Homocysteine S-methyltransferase OX=391009 OS=Thermosipho melanesiensis (strain BI429 / DSM 12029). GN= PE=4 SV=1
--EFLELLNER-IYFLDGAYGTEFFKLGF-KE-VIETLNVTNSEMVYALQKAYVDAGVDFLLTNTFSANRLKLSSKYNLKDINYNAVKIAKKARKD-KYI
LGDISSTGYLISPLGELTFDEAYEVFKEQGEILLNSGIDGFILETMSDLKELKAAILALRDLSDVPIIVQMTFDDGVAVTGTSVEIFSTLMNDLDVDVVG
INCTLEPEKLLPVFKQLSNYSRKPISVEPNAGKPLL-RDGSIVYNTSPEKFALYMEDFVEFGANIVGGCCGTSPEHIRLMVEFLKEKKPKKREI--VKEE
FVSSRTKLKKM---KPFLIIGERINAAGKKKFQQKIRERNYNKIVELAILQEKEGAHVLDLNLGIEKLLDKTHFSQVVNTLDKISSLPLSLDIQEFEFME
MALKEYVGRPIINSSTAKRENLDKAIYLLKRYGGILILLTMKDK-IPESAKERFDIALEAIRYLEKHDIEKERVIVDPLVLPLGAKKDP-AVTIKTIELL
SKE-GINTSIGLSNLSFGMPNREALNSSFLALCIDKGLTAAILNTSEKCTMNAVFGSLTLKGVDF-----------EKKEI----IRNE----------P
MIEMILNKKEDELKREIEKLLEEY-TPLQISQDILSKKMEYIGELYSKGEIYLPQLILAAETVTPIFEYLNSLIE-SNAREKLGTVVLATVEGDVHDIGK
RIVGTVLKSSGINVIDLGKDVPAKEILKAVKEYKPDIVGLSAMMTTTIGRIKEVKDLFVDNNVDIPIISGGASMNKEIADNFGV-YYAKNASQALKLVKK
ILK
>tr|A7HL42|A7HL42_FERNB Homocysteine S-methyltransferase OX=381764 OS=Fervidobacterium nodosum (strain ATCC 35602 / DSM 5306 / Rt17-B1). GN= PE=4 SV=1
--EFHVLISER-VLFLDGAYGTEFFKRGYKKE-PIEILNVKAPEKVLELQSEYVKAGVDFLLTNTFSGNRHKLKKGNYFEQINSEAVRIAKEAAKE-KYI
LGDMSSVGEMIQPIGDLDSKYVYNIFKEQAKVLIESGVDGIIIETMSDLKELKLAYLAVRDVSDIPLFVSMTFENSVAVTGTSLEVYVSLFNDLDVDAIG
INCTLTPDKMVPLVKKLSIFSKKPIFAEPNAGKPLS-ADGRLIYKTTPEEFTVYIEDYVELGANIVGGCCGTGPDHIRYMTKLIGERKPKARKT--EELN
VITNRTYMVEV---SPFLVIGERINAAAKKKLHAQIREFNFENVLKLAKDQEKEGAQVLDVNLGLESVLSDEHFRRIIVELDRIVSLPLSLDIQFNEYLE
VALFEYPGRAIINSAKAIKEDLDAKIRMLKRYGGILIILAMGKE-IPNSPEERYKTAKDAVEYAEKNGIDRSRIFVDPLVLPLGANQDY-NVTLETIKLL
NKE-GIKTSIGLSNFSFGMPNREQLNASFLALAMHYGLSGAILNTSEVTTVNILSGMKKILKKES-----------TNVSV----EDVN----------D
LAKLLLAGDGVNAEKQIMAYLDSM-KPIEVAQNVLTKSMEVIGNLYAQNKIFLPHLILAAETVKPIFNKLLSMIE-EKDSAKLGRVLLATVEGDIHDIGK
KIVATVLESAGFEVIDIGKDVPAKAILEKVKEFNPDIVGLSAMMTTTVVQVGEVVKTLRNNGVTVPVIAGGASMNEDLAKRFGS-LYAKDAQQAVEICKE
LVS
>tr|A9BIZ3|A9BIZ3_PETMO Homocysteine S-methyltransferase OX=403833 OS=Petrotoga mobilis (strain DSM 10674 / SJ95). GN= PE=4 SV=1
--EFAEILNEK-ILILDGGYGTEFIKRGY-KNIPAEILNIEYPEVVYNLQSEYVKSGADILLTNTFSGNRRKLKENEAFEKVNVKAVEIAKQASKG-KLV
FGDLSSLGEYPKPMGALEMDEAIEEYYQQAKVLFESGVDGFIVETMTDIKELKAAVYGIRKVTDLPLIAHMTFENGRSVTGTSVEIFANVFNDLDVDVLG
INCTLGPEDLLKVFERLSLSTNKFLSVEPNAGKPIF-DGKNLEYKMTPEIFGMFVEDYLDLGVNIIGGCCGTSPEHIKVIRNMV-KRRPKKIVK--EIPI
MYSSRTILNKF---HPFTVIGERINPAGNKKFQNEIEEFNFDNVIKRANNQKNAKAHAIDVNLGIEKILNEEHFKKIIIELDKHSSLPISFDIQNIGFLE
SALKEYPGRPIINSSKLSKKDLDRKLELIKKYGGLLIVLALEKE-ILESAEERLQLMLRKWPYIESKGISKDRIIVDPLVLSLAANNDP-NITLETVKLL
SQN-GFNTTMGLSNLSFGLPNRNYINAAFLSRAKSKGLTSAILNPEDEFLMNTLNGNLLLDKNIV-----------IPTKV----EKQD----------E
LTEKILQGEEGEVKRIIENQLKEK-SPLEVSQDVLGKAMEKIGDLYAQGNIYLPELLLAAETVKPIFDYLNNLIP-ESQNDKKAKVVLATVEGDIHDIGK
NIVAAVLRSANFKIIDLGKDVETSIIIDAVQKEKPNILGLSAMMTTTVGKIEDVVNELKKLSLNVKVIAGGASMNRKLAETFGCDAYAKDASEGLKICKS
WVN
>tr|B7IHI6|B7IHI6_THEAB 5-methyltetrahydrofolate S-homocysteine methyltransferase OX=484019 OS=Thermosipho africanus (strain TCF52B). GN= PE=4 SV=1
--EFLQMLNER-IYFLDGAYGTEFFKKGF-KG-VIETLNITDKEMVFDLQKAYVDAGVDFLLTNTFSANRLKLKSKYNIKDINYNAVKIAKQAAGQ-KYV
LGDISSTGFLIEPLGEISFDEAYDVFREQGEILLNAGVDGFIIETMSDLKELKAAILALRDLSDIPIIAQMTFENSKAVTGTSVEIFATLLNDLDVDVIG
INCTLEPEKLLSVFKKLAQYSKKPISVEPNAGKPLQ-RDGSIVYKTSPEKFAIYMEDFVEVGANIVGGCCGTSPEHIRLMIKFLKNRKPKKRKI--IAEE
FVSSRTKLQKI---SPFLIIGERINAAGKKKFQEKIKNKDFSKIVELSSMQEQEGAHVLDVNLGIEKLLDKSHFSLVVNTLDKIGSLPLSLDIQEFEFME
EALKEYVGRPIINSSTAKKEKLDNAIYLLKRYGGVLVLLTMKDK-IPETAKERFEIAKEAVEYLEKNGIERNRILVDPLVLPVGAKKDP-KVTVETIELL
SKE-GLMTSVGLSNLSFGMPNREALNASFLTLCLDKGLNAAILNTSEKCTMNAIFGTLVLKGKEL-----------AKQEF----LKED----------P
LVEMILKKKEKEIKQEIEKLLEEY-SPLQISQNILSKAMEHIGELYSKGVIYLPHLILAAETVTPVFEYLNSLLE-KNDKQKIGTIIVATVEGDVHDIGK
KIVATLFKSSGFNVIDLGKDVPASKILEEVKKHKPDILGLSAMMTTTIGRIKEVKDLLEKEGVKIPIIAGGASLNKEIAENFGV-YYAKNASEGLKLSKK
ILK
>tr|A8F6Y8|A8F6Y8_THELT Homocysteine S-methyltransferase OX=416591 OS=Thermotoga lettingae (strain ATCC BAA-301 / DSM 14385 / TMO). GN= PE=4 SV=1
--EFFQLLQER-VLFLDGAYGTEFFKRGV-NG-LIELLNIEDPEEVQKLHREYIEAGSDIILTNTFSANRLKLRANKDLERININAVKIAKSVSGG-KFV
FGDISSTGNFISPLGNLDFEEAYEVFKEQASLLIEAGVDGIILETMSDLKELKAAIIAVRDLSEIPLIAHMTFEDGKTVSGTSIEIFATLMNDLDVDVVG
INCSLEPDEMLPVFTKLSELSMKPLCVEPNAGKPIL-EKGRLSYKTAPKEFAVYMADFIELGANIVGGCCGTGPEHIKVMCKYIGNQKPRKRQV--KREQ
YLSSRTILRPT---DTFLVIGERINASGRKKLQTKIQQMDFSQVVELSQLQEQEGCDAIDLNFGIEKLLTHDHFRRAIVELDKRSSLPVSFDIQNLQFLE
SAMREYAGRGLINSAFAREDHLEERIRLLKKYGGMLIVLAMEKH-VPETAQQRFKIAMKAAEILKDHDVDLERVYFDPLVLPAGAKNDY-HTTLKAIELM
NRA-GLKTSIGLSNLSFGLANRESVNAAFLALCIEKGLSAAILNSAEATTMNVLRGALQLKGKEP-----------AKTEQ----VIED----------E
LVKLIVSGQKEKLMNFVKDSLKEK-EPLYISQNMLARAMEQIGTLYSRGIIYLPHLILASETVQPAFDYLNNLL--GEAQTKLGKVLLATVQGDIHDIGK
RIVATVLKSGGFEVYDVGKDVPAQKILSECERLKPDIVGLSAMMTTTVGQVKEVSDLLKKNNVRVVVIAGGASMNEQLANQFGV-LYAKDALKALEICKK
IVG
>tr|F7YXH9|F7YXH9_9THEM Methionine synthase (B12-dependent) OX=688269 OS=Thermotoga thermarum DSM 5069. GN=Theth_0531 PE=4 SV=1
--EFHEMLKQR-VLFLDGAYGTEFFKRGY-KD-LIELLNVKNPQAVAQLQKEYVQAGADILLTNTFSANRAKLKAGELFEKINVEAVKIAKSVANG-RLV
FGDISSTGSFVKPLGEMDFDEAYFIFKEQAQLLIESGVDGIIIETMSDLKELKAAILAVRDVSDIPLIASMTFDNGKSVTGTSVEIFSTLMNDLDVDVAS
INCTLEPKDMLNVFIQLAKYCNKYLCVEPNAGKPIL-RGNVLEYKTTPDEFAIYMRDFVEFGANIVGGCCGTGPKHIKSMVEYIGNQKPKSKEP--SKRQ
FVSSRTVMKPV---EDFLIIGERINASGKKKLQVQIQQKDFSTIVQLAQEQEKEGCAVIDVNLGIEKLLEKDHFKQVIIELDRVSALPLSLDIQNLEFLE
TAAKEYVGRPMINSALAREDHLIERLKILKRYGGILIVLTMEKD-IPKTPEERFKLALKAVEIIKKEGVDLDRIFFDPLVLPVGAGNDY-RVTVKTIELL
NSA-GLKTCIGLSNLSFGMPEREKVNAAFLALCMEAGLKAAILNSKETTTMNIIEGMLLLKGKEL-----------AKTKV----EFED----------P
LVEWIVKGQKDKVMDFVKEKLKDL-DPLTVSQQILAKAMERVGKLYSEGVIFLPQLILAAETVQPVFEYLNSLL--TDSKVKLGTVVLATVQGDIHDIGK
KIVATVLRSGGFEVYDLGKDVPADKILESVKKIKPDIVGLSAMMTTTVGRVKEVADLLKENGVNVVVIAGGASMNKELAEKFGV-LYAKDALEGLEVCKK
IVE
>tr|Q9WYA5|Q9WYA5_THEMA Methionine synthase OX=243274 OS=Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099). GN= PE=1 SV=1
--EVSKLLSER-VLLLDGAYGTEFMKYGY-DD-LPEELNIKAPDVVLKVHRSYIESGSDVILTNTFGATRMKLRKGDKLDPIVRNAVRIARRAAGE-KLV
FGDIGPTGELPYPLGSTLFEEFYENFRETVEIMVEEGVDGIIFETFSDILELKAAVLAAREVSDVFLIAHMTFDKGRSLTGTDPANFAITFDELDIDALG
INCSLGPEEILPIFQELSQYTDKFLVVEPNAGKPIV-ENGKTVYPLKPHDFAVHIDSYYELGVNIFGGCCGTTPEHVKLFRKVLGNRKPLQRKK--KRIF
AVSSPSKLVTF---DHFVVIGERINPAGRKKLWAEMQKGNEEIVIKEAKTQVEKGAEVLDVNFGIESQIDVRYVEKIVQTLPYVSNVPLSLDIQNVDLTE
RALRAYPGRSLFNSAKVDEEELEMKINLLKKYGGTLIVLLMGKD-VPKSFEERKEYFEKALKILERHDFS-DRVIFDPGVLPLGAEGKP-VEVLKTIEFI
SSK-GFNTTVGLSNLSFGLPDRSYYNTAFLVLGISKGLSSAIMNPLDETLMKTLNATLVILEKKE-----------LPRAE----VKEE----------K
LVEIILSGNRSELEKLVEDFLKEK-DPLSVIEEHLRPAMERIGELYDKGKIFLPQLILAAQTVKPVFDKLTSMLP-SDSQGE--TFVIATVKGDVHDIGK
NIVASVIRSSGYRVVDLGKDVDTSEIVEAVEKERPVALGLSAMMTTTVGRIKEVVEKLKEKNLKIPVIVGGASLNEKLAKELGADYYAKNASEAVKILKS
LGR
>tr|B9KC48|B9KC48_THENN 5-methyltetrahydrofolate S-homocysteine methyltransferase OX=309803 OS=Thermotoga neapolitana (strain ATCC 49049 / DSM 4359 / NS-E). GN= PE=4 SV=1
--EVAKMLSEK-VLLLDGAYGTEFMKLGH-EE-LPEELNIKAPEVVFKVHRTYIESGSDAVLTNTFGATKMKLRKGNELDSIVRNAVRIARKAAGE-RLV
FGDIGPTGELPFPLGNTLFEEFYENFKETARIMVEEGVDGIILETFSDILELKAAVLAVRDVSDVFLIAHMTFDNGRSLTGTDPVNFALTFDELDVDALG
INCSLGPEEILPIFQELSQYTDKFLVVEPNAGKPIL-ENGKTVYPLKPEDFAVHIDSYYEAGVNIFGGCCGTTPEHIKLFRKVLGSRKPLPRKK--KKII
AVSSPSKLVTF---DHFVVIGERINPAGRKKLWKKMQEGNLDVVANEAKDQVEKGAEVLDVNFGIESQVDPSYVEKVVQSLPYTASVPLSLDVQSLNLAE
RSLRVYPGRPLFNSSKVTEKDLEEKINMLKKYGGVLIVLLMEND-VPKTFEERKKNFEKALKILEEHRFL-DRVLFDPGVLPLGAEGKP-TEVLKTIEYI
SKM-DFKTTVGLSNLSFGLPDRSFYNTAFLVLGISKGLSSAIMNPLDENLMKTLDSTLVILEKKD-----------LPKAE----VRED----------K
LVEAILSGRREDVEKEVENLLKEK-DPLSIIEEHLRPAMEKIGLLYDKGKIFLPQLILAAQTVKPVFDKLASMLS-SENQGE--TFVIATVKGDVHDIGK
NIVASVIRSSGYRVVDLGKDVDTERIVEAVEKEKPVALGLSAMMTTTVGRIKEVVESLKKKGLKVPVIAGGASLNEKLAKELGADYYAKNASEAVKILKS
LGR
>tr|C9MVF0|C9MVF0_9FUSO 5-methyltetrahydrofolate--homocysteine methyltransferase OX=634994 OS=Leptotrichia hofstadii F0254. GN=GCWU000323_00621 PE=3 SV=1
---LQNDLKN-KILLLDGAMGTMIQQEKLTAGGCNDYLVLQRPDVIKNIHKRYLEAGSDIIETNSFGALDIVLKDDDKVFEMNKAAAELVNEAIAENLYV
AGALGPSNKI-SVTGGVTFEELIHSYYTAVSGLMAGGVDLILFETIQDTRNLKAAYLGLKKAMTVPLMLSFTIETGTTLAGQTADAFYYAVNHMNPFSVG
LNCATGPEFMTQFLKTLNNISNTYISVYPNAGLP--NEDGE--YEETPDTLSAKIEPFFQNNLNIVGGCCGTTPEHIQKIKE--KSVNYSPRVID-EN-K
DFNDVSGLIALTPKNRPIYVGERTNVIGSRIFKNLIASEKFDEATEVARLQIKGRADVIDICLA---NPDRDEVADMKAFLDKFAKVPLMIDSTDINVIK
EGLTYLQGKGIINSINLEEKKFADMAKVIKDFGASVVVGLIDEEGMAVSVEKKLKVARRSYELLKKYGIDERDIIFDTLVFPVATGDQKATATIEAIKQI
KAEMNVKTILGVSNVSFGLPGREVLNTYYMQKAYEAGLDYAIVNTEKVMPMDEISDELLFHTNDENVSKFANFYREKKAI---QKVVDTSNLT---TEEK
VSNLVVEGSKKDLIVYLDELLQKYSPI-DIINGPLMTGMDEVGRLFNNNDLIVAEVLQSAEVMKASVSHLEQFMEKDES---KGKVIMATVKGDVHDIGK
NLVGIIIGNNGYEVIDLGINTPAEKIREAIIEHKADFLGLSGLLVKSATEMVNTMGVLHEAGIDIPIFVGGAALTEKFTVNKNNVIYSRDAMTALADLNK
MI-
>tr|L1N7V8|L1N7V8_9BACT 5-methyltetrahydrofolate--homocysteine methyltransferase OX=1127699 OS=Prevotella saccharolytica F0055. GN=HMPREF9151_01769 PE=4 SV=1
IMKIQDLIKQ-RILILDGALGTMIQEYGLEENGNNDILNLTRPDIIMDIHKKYLEAGADLIETNTFSSQIISQADHHLAREMALKGAQLARKAADEPRFV
CGSVGPTNKTCPAARDITYNELFEAYYEQIDALIEGGIDAVLIETIFDTLNAKAAIDASLTAMELPIMLSMTIDAGRTLSGQTIEAFLASISSYPIFSIG
LNCSFGARQMKPYLKELAQKAPYYISAYPNAGLP--NSMGL--YDESAESMAPQMAEFIDEGVNIIGGCCGTTDTFIAKYAALAKGKCPHRVVEP-STTM
WLSGLEHL-NVTPEIGFVNVGERCNVAGSRKFLRLIKEQQYEEAIGIARKQVADGALIIDINMDDGLLDAEKEMVTFLNMIAAIARVPIMIDSSKWSVIT
SGLKCVQGKGIVNSISLKEAQFIKRAQDVKRLGAACVVMCFDEVGQATTFARRIEIARRAYDILLKVGFHPADIIFDPNILAIATGMEEAVDFIQAVRWI
RSNLGAHVSGGVSNLSFSFRNREAMHAVFLYHAIQAGMDFGIVNPASKITYSDIPTDVIFNRKQGATEALIALADRIKAAE-EQQK-GVGDLSEWDLEHR
LKYALRKGIATHLEEDLQEALKQYKQAVDIIEGPLMDGMNEVGELFGAGKMFLPQVVKTARTMKQAVSILQPYIEKQKAASKAGKVLLATVKGDVHDIGK
NIVSVVMACNNYEVIDLGVMVPVEQIVKKAIEERVDIIGLSGLITPSLEEMVNVAIEMQKAGLDIPIMIGGATTSRLHVALGGPVVWMKDASRNAPTASR
LL-
>tr|I9RS77|I9RS77_BACFG Methionine synthase OX=997878 OS=Bacteroides fragilis CL03T00C08. GN= PE=3 SV=1
MKTIQQLVLE-RILILDGAMGTMIQQYNLRENGNNDLLCLTRPDVIRDIHRKYLEAGADIIETNTFSSTTISMADHEYVREMNQAAVKLAREVADEPRFV
AGSVGPTNKTCPAYRAVTYDEMADAYQQQMEAMLESGVDALLIETIFDTLNAKAAILAAERAMKVPVMLSVTVDGGRTLSGQTLEAFLASVQHADIFSVG
LNCSFGAKQLKPFLEQLAARAPYYISAYPNAGLP--NSLGK--YDQTPADMAHEVKEYVHEGINIIGGCCGTTDAYIAEYPALIAGAKPHIPVCK-PDCM
WLSGLELL-EVKPEINFVNVGERCNVAGSRKFLRLINEKKYDEALSIARKQVEDGALIIDVNMDDGLLDAKEEMTTFLNLVASIARVPVMIDSSKWEVIE
AGLKCLQGKSIVNSISLKEEKFLEHARTVRQYGAAVVVMAFDEKGQADTATRKIEVCERAYHLLDKIGFNPHDIIFDPNVLAVATGIEEAVDFIEATAWI
KKNLGAHISGGVSNLSFSFRNREAMHAVFLYHAIQKGMDMGIVNPGTSVLYTDIPVDVVLNRRSDAAERLIELADRLKEAS-AGNTSAGQPVKAWTVEER
LQYALVKGIGDFLEEDLAEALPKYDKAVDVIEGPLMNGMNHVGELFGAGKMFLPQVVKTARTMKKAVAILQPIIESEKVTASAGKVLLATVKGDVHDIGK
NIVSVVMACNGYDIIDLGVMVPAESIVQKAIEEKVDMIGLSGLITPSLEEMVHVAMELEKAGLDIPLLIGGATTSKLHTALHAPVVHLKDASQNAGVAAR
LM-
>tr|E6K7A7|E6K7A7_9BACT Methionine synthase OX=873513 OS=Prevotella buccae ATCC 33574. GN= PE=3 SV=1
-KTIQELVKE-RILILDGAMGTMIQNYHLTEGGNNDMLNITRPDVVKDIFRQYIEAGADIITTNTFSSQRISQADLDYVGEMALQGARIAREVADEPCFV
AGSVGPTNKTCPAARNLTYDQLFDAYCEQIDGLVEGGVDVILIETIFDTLNAKVAIDAALTIMELPIMLSLTIDAGRTLSGQTIEAFLASVSSYPIFSVG
LNCSFGAPQMKPFLEQMAKVAPYYVSVYPNAGIP--NELGL--YDETAGTMAPQIGDFVNEGVNFVGGCCGTTPEFIAAYRPFVEGKTPRRVPSP-TRRM
CLSGLDVLVNIPGESGFTNIGERCNVAGSRKFLRLIKEKQYEEAVAIARKQVDDGALILDINMDDGLLDAKAEMVNFLNMIASIARVPVMIDSSKWEVIV
AGLKCVQGKSIVNSISLKEEQFLAHARDIKRYGAACVVMCFDEQGQATTFDRRIEIAQRAYDLLRKVGIQPQDIIFDPNVLAIATGMEEAMDFIRATRWI
KEHLGAHVSGGVSNLSFSFRNREAMHAVFLYHAISNGMDFGIVNPSAKITYADIPQAVVLNRRRGAGEDLIALAQRILDVK-TVATEGQKGSDEWPLDER
LEYALRKGVADFLEEDLREAMDEYSKAVDIIEGPLMHGMNVVGELFGAGKMFLPQVVKTARTMKRAVAILQPAIEAERRATKAGKVLLATVKGDVHDIGK
NIVSVVMSCNNYEVIDMGVMVPADQIVKKAVAEHVDIIGLSGLVTPSLDEMVNVATELHKAGLHVPIMIGGATTSKLHVALSGPVIWMKDASQNPIVASK
LL-
>tr|D1PGK1|D1PGK1_9BACT Methionine synthase OX=537011 OS=Prevotella copri DSM 18205. GN=PREVCOP_06366 PE=3 SV=1
-KNLREIVKE-KILILDGAMGTEIQKYNLTEGGNNDMLNITRPDVISDIYRRYLEAGADIITANTFSCQRISQADHNCAREMAFEGARLARIECDKPRFV
AGDVGPTNKTCPAAREITYDELFTDVCEQVDGLIEGGADVILIETIFDTLNCKAMIDAALTMMELPVMISLTVDAGRTLSGQTVDAFLASLSPYPIFSVG
MNCAFGAPQMKPFIEHMAQVAPYYISAHPNAGLP--NEMGE--YDETAESMAPQIAEFIDEGVNIIGGCCGTSPEFIAHYARIAEGKKPHQVVEK-PKYM
WLSGLDLL-QVDDSIRFVNVGERCNVAGSRKFLRLINEKNYEEAIGIARKQVADGAAVVDVNMDDGLLDAKAEMVNFLNMIAAIAKVPVMIDSSKWDVIV
VGLKCCQGKCIVNSISLKEEVFLSHARDVLRYGAAVVVMCFDEVGQATTFERRIEIAERAYHLLDKLGMNPLDIIFDPNVLAIATGMEEAVEFIRATEWI
HQNLGAHVSGGVSNLSFSFRTREAIHCVFLHHAQQVGMDFGIVNAKARMDYNKIPEEVVLNRRKGAADELIELAAEIKAQA-DAAKAAAGGVAEWSVEER
LKYALRKGITDFLQQDIDEALAKYPHAVNVIEGPLMDGMNLVGELFGKGEMFLPQVVKTARTMKSAVSILQPHIEAEKQATTAGKILMATVKGDVHDIGK
NIVCVVMSCNNYEIIDLGVMVPAEQIVQKAIDEKVDAIGLSGLITPSLEEMVHVAREMQKAGLRIPIMVGGATTSELHVALDGPVIWVKDASLNAGICAR
FL-
>tr|F3PE68|F3PE68_9BACE 5-methyltetrahydrofolate--homocysteine methyltransferase OX=762984 OS=Bacteroides clarus YIT 12056. GN=HMPREF9445_00277 PE=3 SV=1
-ASIETLVRE-RILVLDGAMGTMIQQYNLTEGGNNDILCLTRPDVIQDIHRKYLVAGADIIETNTFSSTSVSMADHEYVREINLAAVRLAREVADEPRFV
AGSIGPTNKTCPAFRALTYDELAAAYREQMEAMLEAGVDALLIETIFDTLNAKAAIYAAEQAMRVPLMLSVTVDGGRTLSGQTLEAFLASVQHADIFSVG
LNCSFGARQLKPFLEQLAARAPYYISAYPNAGLP--NSLGT--YDQTPAEMADEIREYVHEGVNIIGGCCGTTDEYIAAYSSLIAGAVPHIPASV-PDNL
WLSGLELL-EVKPENNFINVGERCNVAGSRKFLRLINEKKYDEALSIARQQVEDGAQIIDINMDDGLLDAEKEMTTFLNLIASIARVPVMIDSSKWDVIV
AGLKCAQGKSIVNSISLKEEKFLEHARTIKRYGAAAVVMAFDEQGQADTYERRIEVCERAYRLLDKVGFNPQDIIFDPNVLAVATGMDEAVDFIRATGWI
RKNLGAHVSGGVSNLSFSFRNREAMHAVFLYHAIREGMDMGIVNPATSVLYTDIPVDVVLNRRPDAAERLIETAERLKAEE-AAKSSGRSQLPAWTVEER
LKYALTKGIGDYLEEDLAEALKVYPKAVDIIEGPLMAGMNHVGDLFGAGKMFLPQVVKTARTMKKAVAVLQPVIESEKQAASAGRVLLATVKGDVHDIGK
NIVSVVMACNGYEIIDLGVMVPAETIVQRAIEEKVNMIGLSGLITPSLDEMVHVAIELEKAGLDIPLLIGGATTSPLHTALHAPVIHLKDASQNATVAAR
LM-
>tr|K1Y102|K1Y102_9BACT Uncharacterized protein OX=77133 OS=uncultured bacterium. GN= PE=3 SV=1
----------------------------------------------------------------------------------------------------
---MGPTNRTAPGARAVTFDNLVEAYSEQARGLIEGGVDVLLVETIFDVLNAKAALFAIDSVFRIPVMVSGTIDSGRTLTGQTLEAFLVSVSHFPLLSVG
LNCALGAEQLRPFVQELSAKSPFYVSAHPNAGLP--NQFGE--YDQAADYMASIAEGFMKEGVNIIGGCCGTTPKHIRKIAEVAKKYKPRPLPSL-AKQT
KLSGLEVL-AITPETNFVNIGERTNVSGSKKFARLIREEKYSEALAIARDQVEGGAQVIDICMDEAMLDSEKAMVKFVNLVMAISKLPLMIDSSKWDIIE
SALKCIQGKSIVNSISLKEEVFLDHAKKIRKYGAAAVVMLFDEKGQADTYAKRIAVAERCYRLLDRLNFPPEDIIFDPNVLAIATGIEEAVDFIKTTEWI
KQSLYAKVSGGISNLSFSFRDREAIHSVFLYHAIKAGLDMGIVNPGMLQVYTEIPADVVLNRRKDGTERLVKYAEMMQSEA-EGGENGADGVRAWPVVER
IKHALIRGLDEFIEDDVEEARTLFSRSIELIEGPLMGGMNEVGDLFGAGKMFLPQVVKSARVMKKAVAKLAPYIELESEVKSAGKLLLATVKGDVHDIGK
NIVSVVLACNNYQIIDLGVMVPAEKIIDTAIKEKVDFIGLSGLITPSLEEMVHVASEMERRELKIPLLVGGATTSEIHAAVTNSVIHVKDASKAAGVLSA
LR-
>tr|I9T295|I9T295_9BACE Methionine synthase OX=997887 OS=Bacteroides salyersiae CL02T12C01. GN= PE=3 SV=1
MITIPQLVSR-RILILDGAMGTMIQQYNLKEGGNNDLLCLTRPDVIQDIHRKYLEAGADIIETNTFSSTTVSMADHQYVREINLAAVKLAREVADEPRFV
AGSVGPTNKTCPAFRALSYDELADAYQQQMEAMLEGGVDAILIETIFDTLNAKAAVYAAEQAIEVPIMLSVTVDGGRTLSGQTLDAFLASVQHANIFSVG
LNCSFGARQLKPFLEQLAARAPYYISAYPNAGLP--NSLGQ--YDQSPADMAHEVKEYIHEGINIIGGCCGTTDAYIAEYPALIEGARPHVPVRK-PDCL
WLSGLELL-EVKPEINFVNIGERCNVAGSRKFLRLINEKKYDEALSIARQQVEDGALIIDVNMDDGLLDARQEMTTFLNLIASIARVPVMIDSSKWEVIE
AGLKCLQGKSVVNSISLKEEKFLEHARIIRQYGAAAVVMAFDEKGQADTAARKIEVCERAYRLLDKVGFNPQDIIFDPNVLAVATGIEEAVDFINATGWI
RKNLGAHVSGGVSNLSFSFRNREAMHAVFLYHAIQQGMDMGIVNPATSVLYTDIPADVVLNRRPDAAERLIELAEALKASA-QLSTSNSQLSVAWTVQER
LQHALIKGIGDFLEEDLAEALPLYEKAVDVIEGPLMDGMNHVGELFGAGKMFLPQVVKTARTMKKAVAILQPIIESEKQASSAGKVLLATVKGDVHDIGK
NIVSVVMACNGYDIVDLGVMVPAETIVQHAIEEKVDMIGLSGLITPSLEEMVHVAMELEKAGLDIPLLIGGATTSKMHTALHAPVVHLKDASQNAGVAAR
LL-
>tr|F9D186|F9D186_9BACT Exopolyphosphatase OX=908937 OS=Prevotella dentalis DSM 3688. GN= PE=3 SV=1
MGLLDSIARE-KILILDGAMGTMIQDCRLTERGNNDVLNLTRPDIISDIHRKYLEAGADIIETNTFSSQRISQADHAHSREIARQGAVLAKEAARRPRFV
AGSIGPTNKTCPAARAMTYDELLAAYVEQAEALIDGGVDLFLIETIFDTLNAKCAIDACNQAMALPIMLSVTVDAGRTLSGQTLEAFLASVSCYDIFSVG
LNCSFGARQMKPYLKQLAQKAPYYISAYPNAGLP--NSMGE--YDETVESMSPQIAEFVDEGVNILGGCCGTTDAFIRSYYQLSQGKRPHVPQPK-PRTL
WLSGLELL-DVTPEVNFVNVGERCNVAGSRKFLRLIKEKKYDEALDIARRQVEDGALVIDVNMDDGLLDAEAEMVTFLNLIASIARVPVMIDSSKWDVVL
AGLKCVQGKCIVNSISLKEETFLAHARDVKRFGAAVVVMCFDEQGQAATYERRIEIAERAYRLLEKAGFNPLDIIFDPNVLAIATGMEEAVNFIRATHWI
KANLGAHVSGGVSNLSFSFRNREAMHAVFLYHAIREGMDFGIVNPATKVTYSDIPADVVLNRRKNAAEDLIELAEHIKAEQ-LALQEASQGNGAWDLHAR
LVYALRKGIATHLDEDLHEALEQYPHAVDIIEGPLMDGMNKVGELFGSGKMFLPQVVKTARTMKQAVAILQPYIEAEKAAASAGRIILATVKGDVHDIGK
NIVSVVLACNNFEMVDMGVMVPPGHIVKKAIETQADIVGLSGLITPSLDEMVNTAVEMKRAGLTIPILIGGATTSQLHVALDGPVVWTKDAAQCVLASAR
LL-
>tr|E6MLC8|E6MLC8_9BACT Methionine synthase OX=888832 OS=Prevotella salivae DSM 15606. GN= PE=3 SV=1
LKGLQDLIRE-KILILDGAMGTMIQSYHLTEGGNNDLLSLTRPDVILDIHRRYLAAGADIIETNTFSSQRISQADGDISYELAYEGARLARQAVDECRFV
AGAIGPTNKTCPAARDLTYDELYFAYEEQIKGLLDGGVDALLIETIFDTLNAKVAIDVATNAMELPIMLSVTVDAGRTLSGQTLEAFLGSICSYPIFSVG
LNCSFGASQMKPYLKELGKKAPYYISAYPNAGLP--NSMGE--YDETAESMSPQIGEFIDEQVNIVGGCCGTTEEFIRRYAEMARGKAPRKPVER-PKDL
WLSGLELL-EVSPEVRFVNVGERCNVAGSRKFLRLIKEKNYEEALTIARKQVSDGALIIDVNMDDGLLDAQTEMVNFLNLIASVARVPVMIDSSKWDVIV
AGLKCMQGKCVVNSISLKEQEFLRHAREIKRFGAAVVVMCFDEVGQATTFERKIEIAERAYRLLDKVGFNPLDIIFDPNILSIATGIEAAVDFIRATGWI
KKHLGAHISGGVSNLSFSFRNREAMHAVFLYHAINQGMDFGIVNPATKITYADIPSDVVLNRKEGAAEALIELANEIKANE-DARKAGGEVLGEWPVAKR
LEYALRKGISEHLQADLTEALAQYPHAVDIIEGPLMDGMNEVGELFGAGKMFLPQVVKTARTMKQAVAILQPYIEMEKATYKAGKIILATVKGDVHDIGK
NIVGVVMACNNYEVIDLGVMVPAEQIVKRAIAENADMIGLSGLITPSLEEMVNVALEMKKAQLEIPIMIGGATTSQLHVALGGPVVWMKDASQNALIAAK
LL-
>tr|H1HM16|H1HM16_9BACT Methionine synthase OX=999422 OS=Prevotella maculosa OT 289. GN=HMPREF9944_01210 PE=3 SV=1
-KGLRELVKE-RILILDGAMGTMVQSYHLSEGGNNDLLCLTRPDVVLDIHRRYLAAGADIIETNTFSAQSISQADGDICYELSYEGARLARQAADEPRFV
AGAVGPTNKTCPAARDLTYDALFAAYEEQIRGLLDGGVDALLIETIFDTLNAKVAIDVAVSLMDLPIMLSVTVDAGRTLSGQTLEAFLGSISSYPVFSVG
LNCSFGAHQMKPYLKELGKKSPYYISAYPNAGLP--NSMGQ--YDETAESMSPQIAEFMDEGVNIVGGCCGTTDEFIRRYTEMAEGKPSRQPIEK-PESM
WLSGLELL-EVSKEVRFVNVGERCNVAGSKKFLRLIKEKNYEEALTIARKQVTDGALVIDVNMDDGLLDARTEMVNFLNLIASVAKVPVMIDSSKWDVIT
AGLKCMQGKCIINSISLKEAEFVCHARDAKRYGAAIVVMCFDETGQATTYERKIEIAERAYRILDKVGFNPLDIIFDPNILSIATGIEEAVDFIKATAWI
KQHLGAHISGGVSNLSFSFRDREAMHAVFLYHAIHEGMDFGIVNPATKVTYADIPADVVLNRKPGAAEELIELAGRIKAEA-EEAKANGTSVGAWPVDKR
LAYALRKGIGNYMEEDLAEALRQYPHAVNIIEGPLMDGMNEVGELFGEGKMFLPQVVKTARTMKQAVAILQPHIEAEKTSYKAGKIVLATVKGDVHDIGK
NIVGVVMACNNYDVIDLGVMVPAEQIVRKAIAEKADMIGLSGLITPSLEEMVNVAKEMKKAGLDIPIMIGGATTSQLHVALGGPVVWMKDASQNALIAAK
LL-
>tr|G6B1T9|G6B1T9_9BACT 5-methyltetrahydrofolate--homocysteine methyltransferase OX=1002367 OS=Prevotella stercorea DSM 18206. GN=HMPREF0673_02867 PE=3 SV=1
-KKLNEVVKD-RIMILDGAMGTMIQQYALTEGGNNDMLNITRPDVVSDIHRKYLEAGADIITTNTFSSQRISQADHEAAREMAFAGARLARKAADEPRFV
AGSVGPTNKTCPAAREIDYLTLYDVYLEQIEALVEGGADIILIETVFDTLNAKAAIDATMEAETLPIMLSITVDAGRTLSGQTLEAVLASVSSYPLFSIG
LNCSFGAPQMKPFLKELARKSPYYISAYPNAGLP--NSMGE--YDETAESMAPQMQEYVDEGVNIIGGCCGTTEKFIAEYAKIVEGKQPHTPQPK-SQTM
WLSGLELL-DVTPDIRFVNVGERCNVAGSRKFLRLINEKNYDEAVSIARKQVADGALVIDINMDDGLLDAREEMRTFLNIIASIAKVPVMIDSSKWDVIT
AGLQCVQGKAIVNSISLKEEVFLSHARDVMRYGAAVVVMCFDEKGQATTYERRIEIAERAYRLLEKVGMNPLDIIFDPNVLAIATGMSEALDFIRATEWI
RTNLGAHISGGVSNLSFSFRNREAMHAVFLYHAIGKGMDFGIVNPATKVAYGDIPADVVLNRRPDASERLVDLAEKIKLQQ-EALKNGAAGVAEWDVAER
LSTALVKGVADYMEDDLQEALTVYPKAVDIIEGPLMAGMNKVGELFGCGKMFLPQVVKTARTMKKAVAILQPYIEADKKTTTAGKVLMATVKGDVHDIGK
NIVDVVMSCNNYEVIDLGVMVPAEQIVKKAVAENVDMIGLSGLITPSLEEMVNVATEMEHAGLDLPIMVGGATTSEMHVALSGIVVWVKDAAQNPLVAQR
LM-
>tr|G1W9J4|G1W9J4_9BACT Methionine synthase OX=702438 OS=Prevotella oulorum F0390. GN=HMPREF9431_00495 PE=3 SV=1
-KKLQDVIQD-RILILDGALGTMFQTYALSEGGNHDLLNLTRPDVVLDVHRRYLKAGADIIETNTFSAQRISQADGADSYKIALEGARLAKTAAMEPRFV
AGSIGPTNKTCPATRNLTYDELYEAYAEEIRGLLNGGVDAFLIETIFDTLNAKVAIDAAIAIMELPIMISATIDAGRTLSGQTLEGFLGSLSGYPIFSVG
LNCSFGARQMKPFLASLAHKAPYYISVYPNAGLP--NSLGQ--YDESADSMAQQIEEYLDEGVNIVGGCCGTTDEFIAKFSQLAKGRKPHRINAK-SDAM
WLSGLELL-ELTPDIRFVNVGERCNVAGSRKFLRLIENKQYDEALAIARKQVADGAMVIDVNMDDGLLDAKSEMVNFLNLVASVSRVPIMIDSSKWDVIL
AGLKCIQGKSIVNSISLKEEVFLREARDVKRYGAAVVVMCFDEQGQATSYERKIEIAARSYRLLEKVGINPQDIIFDPNILSIATGIEEAVDFIKAVGWI
KKNLGAHVSGGVSNLSFSFRNREAMHAVFLYHAIQQGMDFGIVNPATKMVYADLPKDVVLNKDAEASERLIDLANRVKAEQ-EQRKNGARAVAAWDVAQR
LAYALRKGISDYLEVDLAEARQQYPHAVDIIEGPLMAGMNEVGELFGTGKMFLPQVVKTARTMKQAVAILQPFIEAEKANYVAGKILLATVKGDVHDIGK
NIVGVVMACNNYEVIDLGVMVPAEQIVAEAIAHRVDMIGLSGLITPSLEEMVHVAQEMEKAGLHIPIMIGGATTSQLHVALSGPVVWMKDASQNALVAAH
LL-
>tr|C9PYM3|C9PYM3_9BACT Methionine synthase OX=619693 OS=Prevotella sp. oral taxon 472 str. F0295. GN= PE=3 SV=1
-MKIQDIIKQ-RIMILDGALGTMIQDYNLEENGNNDVLNITRPDLILDIHRRYLAAGADLIETNTFSSQIISQADQHLSRPMALAGARLARKAADEPRFV
CGSVGPTNKTCAAARDITYDQIFDAYREQVGALIEGGVDAILIETIFDTLNAKAAIDATMTEMDLPIMLSMTVDAGRTLSGQTIEGFLASISSYPIFSVG
LNCSFGADQMKPFLKELASKAPYYISAYPNAGLP--NTMGQ--YDETVESMSPQIAQFINEGVNIIGGCCGTDDKFIASYAALAKGKTPHVVVSK-PTSL
WLSGLEML-NVTPEVNFVNVGERCNVAGSKKFLRLIKEGLYDEAISIARKQVTDGALVLDINMDDGLLDAEKEMTTFLNMIAAIARVPIMIDSSKWEVIM
AGLKCAQGKCIVNSISLKEELFIEHGRALKRFGAACVVMCFDEQGQATTFERRIEIAQRAYRILQEVGMNPLDIIFDPNILAIATGIEEAHEFIRSIAWI
RKNLGTHISGGVSNLSFSFRNREAMHAVFLYHAINEGMDFGIVNPSSKITYSDIPTDVILNRKPNAAEALIELANKKKEEE-ERRKAGIASGDQWELDER
LKYALRKGIGDHLDEDLHLALAHFPHAVDIIEGPLMAGMNEVGELFGAGKMFLPQVVKTARTMKQAVAILHPYIEKEKKATKAGKVILATVKGDVHDIGK
NIVAVVMACNNYEVIDLGVMVPAEQIIKKAIEEKADIIGLSGLITPSLEEMINVAQEMEKAGLDIPIMIGGATTSQLHVALGGPVVWMKDASQNSLAAAR
LL-
>tr|F8NCU9|F8NCU9_9BACT Methionine synthase (B12-dependent) OX=688246 OS=Prevotella multisaccharivorax DSM 17128. GN=Premu_2788 PE=3 SV=1
-KRLQDIVKE-KVLILDGALGTVIQGLGLTEGGNNDMLNLTRPDVILGIHRRYLQAGADIIETNTFSSQRISQADHGSARDMALAGARLARQATDTPRFV
AGSVGPTNKTLPASRELTYDELWAAYSEQIDGLVEGGVDAILIETIFDSLNAKCAIDAALQVMELPIMVSISVDAGRTLSGQTLDAFLGSISSYPIFSVG
LNCSFGAREMRPFLEDLARKASYYISAYPNAGMP--NAMGQ--YDETAESMSPLIREWMEDRVNIIGGCCGTDETFIHQYFLLSQGMKPHKPQPK-PTTL
WLSGLELL-DINSDVRFVNVGERCNVAGSRKFLRLIKEKNYDEALSIARKQVEDGALVIDVNMDDALLDARKEMVNFLNLIASISRVPVMIDSSKWEVVT
AGLKCLQGKCIVNSISLKEEVFLSHARDVMRFGSAVVVMCFDEQGQATTYERRIEIAERAYRLLEKVGMNPLDIIFDPNILSIATGIEEAVEFIRATKWI
RTHLGAHVSGGVSNLSFSFRNRESMHAVFLYYAIKAGMDFGIVNPSTRITYSDIPENAILNRYSGAAEKLTELAEHILAEK-EAQKAANNGVSEWSLHDR
LVYALRKGIGDYLQEDLNEALNQFPHAVDIIEGPLMDGMNIVGKLFGDGKMFLPQVVKTARTMKQAVAILQPYIEAERTASTAGCVVMATVKGDVHDIGK
NIVGVVMGCNNYEVIDLGVMVPADQIVKKAISEHADVVGLSGLITPSLDEMVNTVREMGKAGLRIPVLIGGATTSELHTALEGPVVWQKDASQSAVILAK
LM-
>tr|F3QYY2|F3QYY2_9BACT 5-methyltetrahydrofolate--homocysteine methyltransferase OX=762982 OS=Paraprevotella xylaniphila YIT 11841. GN=HMPREF9442_03428 PE=3 SV=1
M--LEEIVKE-RILILDGAMGTMIQRYGLTEGGNNDLLSLTRPDVIRDIHRKYLAAGADIIETNTFSSQRVSMADHDYCREINLAACRIARELADEPRFV
AGSVGPTNKTCPAYRALTFDELVAAYREQMEALLEGGVDALLVETIFDTLNAKAAIYAAEASMKVPLMLSVTVDSGRTLSGQTMEAFLASVSHADIFSLG
LNCSFGAHDLIPFLQVLAHRSPYYISVYPNAGLP--NSMGE--YDQTPTQMAEEMKFFVDKGVNIIGGCCGTTDEYIARFPALAAQGRPHVPAGR-AETL
CLSGLEQF-ELTPEVRFVNVGERCNVAGSRKFLRLVKEKNYEEALEIARKQVEDGALVIDINMDDGLLDARQEMVTFLNLLASISRVPVMIDSSKWDVIT
AGLKCVQGKSIVNSISLKEEVFLAHAREVKRLGAAVVVMAFDEKGQADTYERKIEVCARAYRLLDEVGFNPHDIIFDPNVLAIATGMEEAVDFIRATGWI
RRNLGAHVSGGVSNLSFSFRNREAMHAVFLYHACREGMDMGIVNPATSVMYGDIPSDVVLNRRPDAAERLIELADKLKAEE-AAKAGGAGGGGAWSVEER
LQHALVKGIDSYLQEDLEEAAQSYPHAVDIIEGPLMKGMNTVGELFGAGKMFLPQVVKTARTMKKAVGILQPRIEAGKKAARAGLVLVATVKGDVHDIGK
NIVSVVMACNNYEIVDLGVMTPAEEIVAKAKELHPDIIGLSGLITPSLEEMVHVVGELKRAGLSIPVMIGGATTSRLHTALDGPVIWMKDASQNALTAAR
FL-
>tr|F3PQ17|F3PQ17_9BACE 5-methyltetrahydrofolate--homocysteine methyltransferase OX=763034 OS=Bacteroides fluxus YIT 12057. GN=HMPREF9446_00809 PE=3 SV=1
-ASIEKLVRE-RILILDGAMGTMIQQYNLTEGGNNDLLCLTRPDVVQDIHRKYLLAGADIIETNTFNSTRVSMADHEYVREINLAAAGLARRMADEPRFV
AGSVGPTNKTCPAYRALTYDALAADYREQMEALLEGGVDALLVETIFDTLNAKAAVFAATQAMRVPLMLSVTVDVGRTLSGQTLEAFLASVQHADVFSIG
LNCSFGARQLKPFLEQLARRAPYYISAYPNAGLP--NSLGK--YDQTPADMAHEIKEYIHEGVNIIGGCCGTTDAYIAEYTALVEGVTPHVPAPK-PENL
WLSGLELL-EVRPENNFVNVGERCNVAGSRKFLRLINEKKYDEALSIARQQVEDGAQVIDINMDDGLLDTRTEMITFLNLIASIARVPVMIDSSKWDVIV
AGLKCLQGKSIVNSISLKEEKFLEHARTIQQYGAAVVVMAFDEKGQADTFQRKIEVCERAYRLLDKIGFNPHDIIFDPNVLAVATGMDEAVDFIKAAGWI
RKNLGAHVSGGVSNLSFSFRNREAMHAVFLYHAVREGMDMGIVNPATSVLYTDIPEDVVLNRRPDAAERLIETAERLKAED-TAKASGNVRHASWAVEER
LKYALTKGIGDYLEEDLAEALEQYAKAVDIIEGPLMAGMNHVGDLFGAGKMFLPQVVKTARTMKKAVAILQPVIESEKQSVSAGRVLLATVKGDVHDIGK
NIVSVVMACNGYEIIDLGVMVPAETIVQRAMEEKVDMIGLSGLITPSLDEMVHVALELEKSGLDIPLLIGGATTSQLHTALHAPVIHLKDASQNAAVAAK
LM-
>tr|B5CYG0|B5CYG0_9BACE Putative uncharacterized protein OX=484018 OS=Bacteroides plebeius DSM 17135. GN=BACPLE_01757 PE=3 SV=1
-QTIQQLIRE-RILVLDGAMGTMIQQYNLSEGGNNDLLCLTRPEVIEDIHRKYLVAGADIIETNSFNATSVSMADHAYCREINLAAARLARRMADEPRFV
AGSVGPTNKTCPAFRALTFDELQAAYCEQMEALLEGGVDALLIETIFDTLNAKAAIRAAELSMRVPLMLSVTVDAGRTLSGQTLDAFLASVEHADLFSVG
LNCSFGARQLKPFLEQLASRAPYYISAYPNAGLP--NSLGQ--YDQTPEDMAAEVKEYIEEGVNIIGGCCGTTEQYIAKYQELIQGVQPRVPVKK-HAHL
WLSGLELL-EVSPEINFVNVGERCNVAGSRKFLRLINEKKYDEALSIARKQVEDGALVIDVNMDDGLLDAAQEMTTFLNLVASIARVPIMIDSSKWEVIR
AGLKCVQGKCIVNSISLKEEVFIAHAREVKQLGAAVIVMAFDEKGQADTYSRKIEVCERAYRILDKVGFAPEDIIFDPNVLAVATGIEEAVDFIQATGWI
RKNLGAHVSGGVSNLSFSFRNREAMHAVFLYHAIQQGMDMGIVNPATSVLYTDIPQDVVLNRRPDAAERLIETAERLKQ-E-KE---GTASQELWTVEER
LQYALVKGLSDYLEEDLQEALSRYPNAVSIIEGPLMAGMNHVGDLFGSGKMFLPQVVKTARTMKKAVAILQPYIEAEKETRSAGKVLVATVKGDVHDIGK
NIVSVVMACNNYEIIDLGVMVPAEQIVETAIREKVDIVGLSGLITPSLEEMVHVVTELQRAGLDIPVMIGGATTSKLHTALHAPVVYMKDASQNALVAAK
LL-
>tr|E7RSR1|E7RSR1_9BACT Methionine synthase OX=873533 OS=Prevotella oralis ATCC 33269. GN= PE=3 SV=1
-MTLRDAAAQ-RILILDGAMGTMIQDYGLTENGNNDVLNLTRPDVIMDIHRRYLQAGADIIETNTFSSQRISQADRGYAVRLSLEGARLARQAANEPRFV
AGSVGPTNKTCPAARELTYDDLYQAYTEQIEALVEGGVDALLIETIFDTLNAKVAIDAAQSVMSLPIMLSVTVDAGRTLSGQTLEAFLASISTYDIFSVG
LNCSFGARQMKPYLKELARKAPYYISAYPNAGLP--NSMGL--YDETAESMTPQIGEFIDEGVNIVGGCCGTTDEFIARYARWAQGKKPRRVVAK-PKTM
WLSGLELL-DETPEVQFVNVGERCNVAGSRKFLRLIKEKNYEEAMSIARKQVEDGALVIDVNMDDGLLDAKAEMVTFLNMIAAIAKVPVMIDSSKWDVIV
AGLKCCQGKCVVNSISLKEEKFIEHAKDVQRYGAAVVVMCFDERGQATSFERRIEIAGRAYRILEKVGMNPLDIIFDPNILAIATGMEEAVDFIKSVEWI
KNNLGAHVSGGISNLSFSFRNREAMHAVFLYYAIKAGMDFGIVNPAAKVMYTDIPEEVVLNRRKNASEDLIELADRLKKEA-EEASAR-QNVGGWPVDKR
LGYALRKGIGDYLDEDIREALKVYPRAVDIIEGPLMAGMNEVGELFGAGKMFLPQVVKTARTMKQAVYILQPYIEGEKKSSKAGKVILATVKGDVHDIGK
NIVSVVMSCNNYEVIDMGVMVPAEHIVKKAIEEKADLIGLSGLITPSLEEMVNVAVEMRRAGLDIPIMIGGATTSQLHVALSGPVVWMKDASQNALAAAK
LL-
>tr|I9RDU7|I9RDU7_9BACE Methionine synthase OX=997877 OS=Bacteroides dorei CL03T12C01. GN= PE=3 SV=1
-ATLKQIINE-RVLILDGAMGTMIQRYNLSEGGNNDLLCLTRPDVIKDIHRKYLEAGADIIETNTFNAQRISMADHDLCREINLAAARLARELADEPRFV
AGSVGPTNKTCPALRALTYDELATAYQEQMEALLEGGVDALLIETIFDSLNAKAAIYAAETAMEVPLMLSVTVDAGRTLSGQTLDAFLASVQHAPIFSIG
LNCSFGAKQLKPFLEGLAARAPYYISAYPNAGLP--NSLGQ--YDQTPEEMASEVKEYIDEGVNIIGGCCGTTEEYIAKYQELIVSVPPHIPATT-PERL
WLSGLELL-EQTPEMNFINVGERCNVAGSRKFLRLINEKKYEEALSIARKQVEDGALVIDVNMDDGLLDAREEMTTFLNLVMSIARVPIMIDSSKWEVIE
AGLKCLQGKSIVNSISLKEEKFIEHARLIKKLGAATVVMAFDEKGQADTFERKIEVCARAYKILEQVGFNPHDIIFDPNVLAVATGIEEAVDFINATGWI
KKNLGAHISGGVSNLSFSFRNREAMHAVFLYHAIRQGMDMGIVNPATSVLYTDIPADVVLNRRPDAAERLIETAEALKN-T-AT---GTEAVKVWPVEKR
LQYALIKGIGDHLEEDLAEAVKLYPKAVDIIEGPLMEGMNRVGELFGAGKMFLPQVVKTARTMKKAVAILQPLIEADKQARSAGKVLMATVKGDVHDIGK
NIVSVVMACNNYEIIDLGVMVPAEMIVRKAIEEKVDIIGLSGLITPSLEEMAHVAVELKRAGLDIPIMIGGATTSKLHTALGGPVIHMKDASQNALVAAR
LL-
>tr|F0R3V0|F0R3V0_BACSH Methionine synthase OX=667015 OS=Bacteroides salanitronis (strain DSM 18170 / JCM 13567 / BL78). GN= PE=3 SV=1
-KTIQEQINE-RILVLDGAMGTMIQQYGLTEGGCNDVLCLTRPDVIADIHRKYLDAGADIIETNTFNATRVSMADHGYCAEINREAARLARRLADEPRWV
AGSVGPTNKTCPAYRALTFDGLAGAYLEQMTALLEGGVDTILIETIFDTLNAKAAICAAEQAMKVPLMLSVTVDGGRTLSGQTLDAFLASVQHADIFSIG
LNCSFGARQLKPFLEQLARRAPYYISAYPNAGLP--NTLGQ--YDQTPEEMEGEVKEYIDEGVNIIGGCCGTTEAYIRRFASLVEGRKPHQRVDA-SKYL
WLSGLELL-EVTPEINFVNVGERCNVAGSRKFLRLINEKKYEEALSIARKQVEDGALVIDINMDDGLLDAAQEMTTFLNLIASIARVPIMIDSSKWDVIL
AGLKCVQGKGIVNSISLKEAVFIERARTIKRYGAAVIVMAFDEKGQADTYERKIEVCSRAYRILEQVGFRPQDIIFDPNVLAVATGMEEAVDFIRATGWI
RKNLGAHISGGVSNLSFAFRNREAMHAVFLYHAIAQGMDMGIVNPASSVLYTDIPADVVLNRRADAAERLIEMAEKLKT-E-KE---NAGAVQAWTVDSR
LQYALVKGIGDYLEEDLQEALHTYPDAVSIIEGPLMEGMNRVGELFGSGKMFLPQVVKTARTMKKAVSILQPYIEAQKKAKKAGKVLVATVKGDVHDIGK
NIVSVVMACNNYEIIDLGVMVPAEKIVETAIREKVDIVGLSGLITPSLEEMVHVVRELDRAGVHIPVMIGGATTSKLHTALHGPVIYMKDASLNAPVAAR
LL-
>tr|K9EIG5|K9EIG5_9BACE Methionine synthase OX=742727 OS=Bacteroides oleiciplenus YIT 12058. GN=HMPREF9447_03779 PE=4 SV=1
-SKLGSLVRE-RILILDGAMGTMIQQYNLTEGGNNDLLCLTRPDVIRDIHRKYLTAGADIIETNTFSSTSVSMADHQYVREMNLAAVKLAREVADEPRFV
AGSIGPTNKTCPAMRALTYDELADAYREQMEALLEGGVDALLIETIFDTLNAKAAIFAAEKAMQVPVMLSVTVDGGRTLSGQTLEAFLASVQHADIFSVG
LNCSFGARQLKPFLEQLAARAPYYISAYPNAGLP--NSLGQ--YDQTPADMAHEVKEYIHEGINIIGGCCGTTDAYIAEYPALVAGAAPHIPAPK-PDSL
WLSGLELL-EVTPEKNFINVGERCNVAGSRKFLRLINEKKYDEALSIARQQVEDGAQVIDVNMDDGLLDAQAEMTTFLNLIASIARVPVMIDSSKWDVIV
AGLKCLQGKSIVNSISLKEEKFLEHARTIKQYGAATVVMAFDEKGQADTYERKIEVCARAYQLLEKVGFNPHDIIFDPNVLAVATGMDEAVDFIQATGWI
RKNLGAHVSGGVSNLSFSFRNREAMHAVFLYYAIREGMDMGIVNPATAVLYTDIPSDVVLNRRPDAAERLIETAEQLKATE-QQKGNVSDKHVSWTVEER
LKYALTKGLGDYLEEDLAEALKLYPKAVDIIEGPLMAGMNYVGELFGAGKMFLPQVVKTARTMKKAVAILQPIIEAEKQSSSAGKVLLATVKGDVHDIGK
NIVSVVMACNGYEIIDLGVMVPAETIVQRALEEKVDMIGLSGLITPSLEEMVHVAMELEKVGADIPLLIGGATTSQLHTALHAPVVHLKDASQNATVAAR
LM-
>tr|G6AEF9|G6AEF9_9BACT Methionine synthase OX=857291 OS=Prevotella histicola F0411. GN=HMPREF9138_00486 PE=3 SV=1
-MSIRDSIKE-RILILDGAMGTMIQGYNLTEGGNNDMLNLTRPDVIEDIHRRYLKAGADIITTNTFSSQRVSQADHSSARDMALEGAKIARKCADEPRFV
AGSIGPTNKTCPAKRDLTYDSLFESYSEQVAAMIEGGIDVILIETIFDTLNAKVAVDASISEMDLPVMLSVTIDSGRTLSGQTLDAFLASVSSYPIFSIG
LNCSFGAEQMRPYLKELSAKAPYYISIYPNAGLP--NSMGL--YDETADTMVPQMATYIDDKVNIIGGCCGTTDDFIAGYAKIVKGKSPHIPVEW-PKEI
ILSGLEQF-RLSPEITFVNVGERCNVAGSRKFLRLIKEKNYEEALTIARKQVDDGALVLDINMDDGLLEAKEEMVHFLNMVSSIARVPLMIDSSDWSVVV
AALKCVQGKSIVNSISLKEDSFIQHAKDVLRYGAAVVVMCFDEEGQATSFERRIEIASRAYKILEKVGFPAQDIIFDPNILAICTGMKEALDFIRAAEWI
KKNLGAHVSGGVSNLSFSFRNREAMHAVFLYHAIQAGMDFGIVNPATKVTYADIPEDVVLDRVEGSDELLIDLANKILEQK-DEQVED--GVNAWSLEER
LVYALRKGISTYLNEDIHEALQKYSRAVDVIEGPLMRGMNEVGDLFGAGKMFLPQVVKTARTMKDAVAILQPYIEKEKVKAIAGKVLLATVKGDVHDIGK
NIVGVVMACNNYEVIDMGVMVPADKIIKKAKEEKVDLIGLSGLITPSLQEMVNDVVAFKEAGLKIPVMIGGATTSQLHVALDSPVVWIKDASVNPSIAAV
LL-
>tr|G1VAR9|G1VAR9_9BACT Methionine synthase OX=563031 OS=Prevotella sp. C561. GN=HMPREF0666_00502 PE=3 SV=1
-MKLRDNIKD-RILILDGAMGTMIQGYHLTEGGNNDMLNLSRPDIIEDIHRRYLEVGADIISTNTFSAQRVSQADHSFSRDIAYAGAKLARKCADEPRYV
AGSIGPTNKTCPAKRDLAYDALFDAYSEQVAAMIEGGIDAVLIETIFDTLNAKVAIDASLSEMDLPIMLSVTIDSGRTLSGQTLDAFLASVSSYPIFSVG
LNCSFGAEQMRPYLKELAAKAPYYISIHPNAGLP--NSMGE--YDETPEIMVPQMASFVDEGVNIIGGCCGTTEEFIAGYVKVVEGKKPHIPVDA-PKEM
ILSGLEQF-RLTPEISFVNVGERCNVAGSRKFLRLVKEKNYEEALTIARKQVDDGALVLDINMDDGLLEAKDEMAHFVNMISSIARVPLMIDSSDWEVVV
SALKCVQGKAIVNSISLKEEVFIRHAKDVLRFGAAVVVMCFDEEGQATSYERRIEIAERAYKILEKVGFPPQDIIFDPNILAICTGMKEAVDFIRATEWI
KKNLGAHVSGGVSNLSFSFRNREAMHAVFLYHAIQVGMDFGIVNPATKVTYADIPEDVVLDRVEGADELLIELANKILEEK-EAQKNG--GATAWALEDR
LKYALRKGISTYLNEDIHEALEKYPHAVNIIEGPLMQGMNEVGDLFGAGKMFLPQVVKTARTMKDAVAILQPYIEKEKVKAIAGKVLLATVKGDVHDIGK
NIVGVVMACNNYEVIDLGVMVPADQIIKKAKEENVDLIGLSGLITPSLQEMVNSVVAFKEAGLNIPVMIGGATTSQLHVALDAPVVWVKDASVNPSIAAA
LL-
>tr|I0TF63|I0TF63_9BACT Methionine synthase OX=1095752 OS=Prevotella sp. oral taxon 306 str. F0472. GN= PE=3 SV=1
-MTIRDSIKE-RILILDGAMGTMIQGYKLTEGGNNDMLNLTRPDIIEDIHRRYLKAGADIISTNTFSAQRISQADHDFSYDIALLGAKLARKCADEPRFV
AGSIGPTNKTCPAKRDLTYDTLFHAYSEQVEAMIKGGIDAILIETIFDTLNAKVAIDASLSEMDLPIMLSVTIDSGRTLSGQTLEAFLASISSYPIFSVG
LNCSFGAEQMRPYIKELASKAPYYISIYPNAGLP--NSMGE--YDETAEVMVPQIQTYVDEGVNIIGGCCGTTDEFIAGYTKIVKDQLPHVPTPV-SKEM
ILSGLEQF-RLTPEITFVNVGERCNVAGSRKFLRLIKEHNYEEALTIARKQVDDGALVLDINMDDGLLEAKDEMVHFVNMISSIARVPLMIDSSDWDVVV
AALKCVQGKSIVNSISLKEETFIRHAKDVLRYGAAVVVMCFDEEGQATSFERRIEIASRAYKILEQVGIQAKDIIFDPNILAICTGMKEAVEFIRATEWI
KKNLGAHISGGVSNLSFSFRNREAMHAVFLYHAIQVGMDFGIVNPATKITYADIPQDVVLDREEGADEKLIELANRILAQK-DILKQN--GKEEWSLEDR
LVYALRKGISNYLNDDIHEALEKYPNAVSIIEGPLMRGMNEVGDLFGAGKMFLPQVVKTARTMKDAVAILQPYIEKEKVKATAGKVLLATVKGDVHDIGK
NIVGVVMACNNYEVIDMGVMVPADKIIKKAKEECVDLIGLSGLITPSLHEMVNDVIAFKEAGLHIPVMVGGATTSKLHVALDAPVVWVKDASVNPSIAAS
LL-
>tr|B3JGL1|B3JGL1_9BACE 5-methyltetrahydrofolate--homocysteine methyltransferase OX=470145 OS=Bacteroides coprocola DSM 17136. GN= PE=3 SV=1
---MQQLINE-RILVLDGAMGTMIQQYNLSEGGNNDMLCLTRPDVIEEIHRKYLEAGADIIETNTFNATAVSMADHAYCREINLAAARLARKIADEPRFV
AGSVGPTNKTCPAFRALTFDELSEAYREQMEALLEGGVDAILIETIFDTLNAKAAVLAAETAMKVPLMLSVTVDAGRTLSGQTLDAFLASVQHADIFSIG
LNCSFGARQLKPFLEQLARRAPYYISAYPNAGLP--NSLGQ--YDQTPEEMAAEVKEYIDEGVNIIGGCCGTTEAYIAKYQELIKDAKPHAPAPK-PDYL
WLSGLELL-EVTPEINFVNVGERCNVAGSRKFLRLINEKKYDEALSIARKQVEDGALVIDVNMDDGLLDAAEEMTTFLNLVASIARVPVMIDSSKWEVIL
AGLKCVQGKCIVNSISLKEEAFVEHARTVKQYGAAVIVMAFDEKGQADTFERKIEVCERAYRILEKVGFRPQDIIFDPNVLAVATGIEEAVDFIKATGWI
RRHLGAHVSGGVSNLSFSFRNREAMHAVFLYHAIQQGMDMGIVNPGTSVLYTDIPSDVVLNRRPDAAERLIETAEKLKA-E-KE---NSGEQQAWTVEER
LQYALVKGLGDYLDEDLHEALAKYPDAVSIIEGPLMSGMNHVGDLFGSGKMFLPQVVKTARTMKKAVAILQPYIETEKKARSAGKVLLATVKGDVHDIGK
NIVSVVMACNNYEIIDLGVMVPAEKIVETAIREKVDIIGLSGLITPSLEEMVHVVSELERAGLDIPVMIGGATTSKLHTALHAPVVYMKDASLNAPVAAR
LM-
>tr|E4T592|E4T592_PALPW Methionine synthase (B12-dependent) OX=694427 OS=Paludibacter propionicigenes (strain DSM 17365 / JCM 13257 / WB4). GN= PE=3 SV=1
-MNLRTILEN-RILILDGAMGTMIQRHKLNEGGNNDLLVLTQPDIIYGIHNQYLEAGADIIETNTFNAQRISMEDGDLVREINIEAAKLARKAADEPRFV
AGAVGPTNKTAPAFRAVSFDDLVAAYKEQILALIEGGVDALLIETIFDTLNAKAAIFAAEEAMRVEIMLSATVDSGRTLSGQTIRAFLASIGHANILSVG
LNCSFGAKDLKPYLHEINEHSPWFVSAYPNAGLP--NQFGE--YDETPETMAIQVKEYFDEKVNIIGGCCGTSPDHIATYSALIENKEVRKPGLA-SKKL
ELSGLEEL-EIEDSSLFVNIGERCNVAGSRMFLRLINEKKYEEALSIARKQVEDGAQVIDINMDDAMLESKEEMVTFLNYVAAISRVPIMIDSSKWEVIE
AGLKCVQGKCIVNSISLKEEEFLYKARKIRAYGAAVVVMAFDEQGQADSFDRKTQICSRAYHLLDKIGFPPQDIIFDPNVLAIATGIEEGVDFINATRWI
KQNLYAKISGGVSNLSFSFRNREAIHSVFLYYAIKEGMDMGIVNAGMLQIYQDIEPEIVLNRRPDATERMIELAEKVKN-Q-AS---GEKVEKEWTLQGR
LEHALIKGISEFLEEDLSEALTQFDTAIEIIEGPLMSGMNIVGELFGEGKMFLPQVVKTARTMKKAVAILQPEIEKQKVSSSAGKFLIATVKGDVHDIGK
NIVAVVLACNNFEVIDLGVMTPTEKIIQTAIDEKVDMVGLSGLITPSLEEMAHVATEMQKAGLSIPLLIGGATTSKVHTAVGGPVVYVKDASVNTHVVAQ
LM-
>tr|G5G9A8|G5G9A8_9BACT Methionine synthase OX=679199 OS=Alloprevotella rava F0323. GN=HMPREF9332_00159 PE=3 SV=1
M--LKEAVKD-RILILDGALGTMIQKYGLSEGGNNDLLVLSRPDVIREIHTRYLEAGADIIETCTFNSQSISLADHSLVKEINFVAAQLARTCADKPRFV
TGSVGPTNKTCPALRALQFDELAAAYQEQIEALLEGGVDAILIETVFDTLNAKAAVVAAQAAMEVPIMLSVTVDGGRTLSGQTLEAFLASFSTMPIFSVG
LNCSFGAKDMKPFLENLAAKAPYYISVYPNAGLP--NSLGE--YDETPEHMASEIAEFLDENINIVGGCCGTTDKFIAEYSKLLKGRTPHQPVAA-PTCL
WLSGLESC-EVRPERNFTNIGERCNVAGSRKFLRLVSEKNYDEAIGIARKQVEDGAQVIDINFDDGLLETKEEMVHFLNLLASVARVPFMIDSSKWDVIL
AALKCVQGKSIVNSISLKEETFLSHARDIQKYGAAVVVMAFDETGQATSFERKIEICKRAYNLLQKLHFNPNDIIFDPNVLSICTGISEGFDFIRAVAWI
RENLGAHVSGGISNLSFSFRNREAMHTVFLYHAIQNGLDMGIVNPSSTITYSDIPKDVILNTR-DASEELISLAQQMTDQQ-KNKVEHSQKTEEWPLEKR
LSYSLRKGIDSNLEEDLSEALGKYAHAVDIIEGPLMDGMNEVGDLFGAGKMFLPQVVKTARTMKKAVSILQPHIEAEKKN-SAGKVLMATVKGDVHDIGK
NIVGAVLSCNNYAIEDLGVMVAPEDIAEKALGIEADVVGLSGLITPSLDEMTKTVVMMKERGIEIPVLLGGATTSRLHTALDGPVIWVKDASQMVIAMSK
FS-
>tr|D5EZ62|D5EZ62_PRER2 5-methyltetrahydrofolate--homocysteine methyltransferase OX=264731 OS=Prevotella ruminicola (strain ATCC 19189 / JCM 8958 / 23). GN= PE=3 SV=1
-KKLNEIIKQ-RILILDGGMGTMIGAVM----GNSDELNLTHPEIVSDIYRKYLEAGADIITTNTFSSQRISQAEHDRAHEMACESARLARQLANEPRFV
AGSIGPTNKTLPAFRDVTYDEMLEAYQEQADGLIEGGVDTLLIETIFDSLNAKCAIDACMRAMELPIMVSVTVDAGRTLSGQTLEAFLASVSTYPIFSIG
LNCSFGATQMKPFIRELAQKAPYYISCHPNAGLP--NALGL--YDETAESMAPKMGELVDEGVNIIGGCCGTTDEFIRLYGPLVVGKKPHVPAPK-PHSM
WLSGLELL-EVNLEARFTNVGERCNVAGSRKFLRLIKEKKYNEAISIARKQVADGALVIDINMDDGLLDAKQEMTTFLNMIAAIAKVPVMIDSSNWEVIK
AGLKCVQGKSIVNSISLKEQKFIEHAQDVMRYGAAVVVMCFDEEGQATTYERRIEIASRAYKILEQVGMNPLDIIFDPNILAIATGMEEAIDFIRATEWI
KQNLGAHVSGGVSNLSFSFRNREAMHAVFLYHAIQVGMDFGIVNPSTKVTYADIPQDVVLNRKKGASEVLIELAGKILEEE-LAKKEAGGATSDRPVEER
LAQALIKGDGTFLEEDLKEALPKFTHAVQIIEGPLMAGMNTVGTLFGEGKMFLPQVVKTARTMKQAVDILQPYIEAEKNTTSAGKVLLATVKGDVHDIGK
NIVNVVMACNGYEVLDMGVMVPAEQIVKKAQEEHVDMIGLSGLITPSLEEMVNVAEELKKAGLDIPIMIGGATTSELHVALGGPVVWMKDASQNALVAQK
LL-
>tr|L0WZK9|L0WZK9_9SPIR 5-methyltetrahydrofolate--homocysteine methyltransferase OX=1204472 OS=Brachyspira sp. 30446. GN=A966_10772 PE=4 SV=1
---LSELIKE-RYLIIDGATGTELQKKDIKKGGCNEILNITAPYIMKEIHTDYLNANANIIKTNSFGAIPWVLSEDDKTYELAKKAALIANEAREEDIFI
AGSLGPGVKL-PSLGQITFDEMYNGYIEAARGLIEGGADIILLETAQDVLQLKSAIIAVNDTAEIPIMVSVTIEEGTMLLGTDIETAYTILSNLDIFSIG
MNCGTGPDMASRHIKKLSEISCLPISIHTNAGLPE-NRDGKAYYSMTPEEFADINSKFFELDLSFIGGCCGTTPLHIEELAKKVKGVKPKKTALE-KPIP
YIASLFNTVSIKQNPAPLMIGERSNATGSKIFRELMIAGDMDGMLDVGIKQVKAGSHAIDVNAA---WAGRDEVEDITKIISSQISLPLVIDAIKPNVIE
AALKVYGGKPIINSANMEEEKFDAICSLAKKYGASIMLLTIDEKSMAFTCEDKLKMAERMYERANVHKILPHDIIFDPLTFTLASGDEKGVETLNAIKEL
SKKYECSISLGVSNISFGLKARKIMNSVFLYEAINHGLTTAIVNVAQILPLSKIDEKLIYNKSNSK-EPLINYINHFSDKE-KKELNTEENIP---IREA
IRDAMLDGEWKDMQVLLNEVKENSEEFQAIIDEILLPTMADIGVKFGEGTIQLPFVLGSAEVMKKSVDFLSEFLEKKKQ---TAKIILGTVAGDVHDVGK
NLVEIIIKNNGFETVNIGTKVSIEKFLEAYHEHNADCIGMSGLLVKSTEVMKDNLAYIRDKGLKIPILLGGAALTKDFVENGDTIFYCKDGFDDILAIKE
II-
>tr|I0IPX1|I0IPX1_LEPFC 5-methyltetrahydrofolatehomocysteine methyltransferase OX=1162668 OS=Leptospirillum ferrooxidans (strain C2-3). GN= PE=4 SV=1
MKPLLERLKY-EVLLLDGSM---LQS----------LWNIEKPQEIQAVHTEYVNAGSDIILTNTFGASRLRLSENDRIREINFQA-DLAQRAS--KAYV
AGDIGPSGT----FGDLPFDDAIAIFYEQAKLLLEAGADLIAIETMFDIQEM---LIGVREAT-IPLMALMTFMDGITDSGSDPETAASVLEGFGVDIMG
LNCSVGPEAMVPVVSRLGQTTDT-IAVEP--GLPV-HRNGETLYLTGAEEVAKFAPSFVEAGANIIGGCCGTTPEYIRILAKTVKGASPI-SRPT-P--L
-ISSRTSMTLIGDGVPFLIVGEKINPTGKKIFSEAIANGQVDLIVAEARKEAEAGAGALDVNVG---VNEAEMMAKAITAIQNVVSLPLVIDSSYASALE
SGLKLYPGRALVNSVNAE-ERLEEVLPL-RKYGAAVIAL-VSGDNIPETAAERMKNAEKILRR-EELGLKPRDLIFDTLALTVSAVQEA-KQTLDTITLI
KKELRLPTILGLSNVSFGLP-RKIVHNNFLSMAIGAGLDAAIC-PYDQVLHQTI----LFARRDPDCR-------------------------A-TTSEA
IRQAILEGERDG-AALCQKGLDE----FTIFLDIMTPAIRHLGDLFGQRVKFIPHLIAGADA-KKGVEVLQP-LEA---VEPKGCVVFATVKGDIHDIGK
NICILMLRNFGFSVIDLGRNVPLDDILAAAEKHQAQIIALSALMTTTMMQMKTAIETIREKNLPYKVMVGGAVVTPKFST--------KDVGDVV-----
---
>tr|C6HW85|C6HW85_9BACT 5-methyltetrahydrofolate--homocysteine methyltransferase OX=412449 OS=Leptospirillum ferrodiazotrophum. GN=UBAL3_80290066 PE=4 SV=1
MIPLLERLKK-DILILDGSM---LQG----------LWNLERPKDIQAVHAEYRAAGSDILLTNTFGASRRRLAEQGRIREINHAG-ELARRAA--KAYI
AGDIGPFGS----FGDTTFEEAVGIFREQASILAEAGVDLIAIETMFDIQEM---LIGVREGA-VPIMAFMTYADGITDSGSDPETVAAVLEGFSVEIMG
LNCSVGPEAMLPVLERLGRATHT-LGIEP--GLPV-HRDGKTVYPLGASEMASFAPAFADAGANIVGGCCGTTPDYIRLISKILKGRPPR-LRTP-S--T
-IASRTRVVPIGAGAPFVLIGEKINPTGKKLFSEAIAEGRTDMIVAEARKEAAAGAHALDVNVG---VDEALMMEKAVIAIGNVVSTPLVIDSSFASALE
SGLRIYPGRALVNSVNAE-ERLEEVLPL-RRYGASVIGL-LSGDDIPEKAIDRMKNAEKILKA-ERFGLSPRDIVFDTLALTVSAVQEA-RQTLETIRLL
KSEWNAHTVVGLSNVSFGLP-RKTVHDTFLAMAIGAGLDGAIC-PYDPLLHQTV----LFSGRDPECR-------------------------PDTTRER
IERAIIEGEREA-TPLVETALAE----FEIFVDVMTPAIRRLGDLFGARQKFIPHLIAGADT-KKGVEVLQP-LEA---TEPKGTIVFATVKGDIHDIGK
NICILMLRNFGYRVIDLGRNVPLETILETAEKEKAQIVALSALMTTTMIQMKVAVDAIREKSLPYKVMVGGAVVTPKFSA--------KDVGEVV-----
---
>tr|C7N1R7|C7N1R7_SLAHD Methionine synthase (B12-dependent) OX=471855 OS=/ RHS 1) (Peptococcus heliotrinreducens). GN= PE=4 SV=1
AAVLR---GE-AYLVFDGAM---LQA----------LLCLTDPAGVTAIHRQYVEAGSQAITTNTFGANARKLG-D-TVEDVFAAA-ACARESG--R-YV
AGDIGPTGG----LGTMSFDEAYDLFAQEVRAADAAGADLLVIETMADLLEM---VLAAKENS-LPIFATMTFEDGRTFLGTSPQIAALTLDALGVNVLG
VNCSLGPSDLQPIVSAMLETATC-VMAQA--GLPS-VVDGHTVYSIMPDEYANAVQAMVDEGVSVIGGCCGTNPDYIRQLAAMVEGKRPP-HREV-E--F
-LTSAQNAVVLGREVA--VIGERINPTGKKRLKEALRTKDYNYVLNEAISQTEAGADVLDVNAG---IDEAATLVTLVGQIQGVSGLPLQIDSADPAAVE
AAVRVYSGKPLINSVNGK-ESLDAVLPV-KHYGCAVVGL-LDENGIPPTGEERFAIAARIVEA-EAYGIPRSHVAIDCLVMAASTNQQE-VEILKGVTLV
KERLGVRTVLGVSNVSFGLP-REIVNATFLSAAFAAGLDMPIL-PMATRYKEVV----VLCAQDEGAA-------------------------PGEDDGS
IRHLIITGRKGD-VQATQALLAD----MEVINEHLIPALDEVGALFEKGTFFLPQLMASAEA-KAGFDVIRS--AS---VDEKGSVAVATVKGDIHDIGK
NIVRMLLENYGYRVYDLGRDVDPELIVQTVQEHDIKLVGLSALMTTTVHNMEEAIKLLREKAPDVKVMVGGAVLNPEYAR--------KDAAESA-----
---
>tr|Q8VJP7|Q8VJP7_MYCTU 5-methyltetrahydrofolate-homocysteine methyltransferase OX=1773 OS=Mycobacterium tuberculosis. GN= PE=3 SV=1
-------------MVGDGAMGTQLQAADLTLGGCNEILNETRPDVLETIHRNYFEAGADAVETNTFGCNLSNLGDDDRIRDLSQKGTAIARRVADEKRYV
LGSMGPGTKL-PTLGHTEYAVIRDAYTEAALGMLDGGADAILVETCQDLLQLKAAVLGSRRAMHIPVFAHVTVETGTMLLGSEIGAALTAVEPLGVDMIG
LNCATGPAEMSEHLRHLSRHARIPVSVMPNAGLPVGAKGAE--YPLLPDELAEALAGFIAEFLSLVGGCCGTTPAHIREVAAAVANIKRPERQVS-YE-P
SVSSLYTAIPFAQDASVLVIGERTNANGSKGFREAMIAEDYQKCLDIAKDQTRDGAHLLDLCVD---YVGRDGVADMKALASRSSTLPIMLDSTETAVLQ
AGLEHLGGRCAINSVNYEESRFAKTMALVAEHGAAVVALTIDEEGQARTAQKKVEIAERLINDIGNWGVDESSILIDTLTFTIATGQEEGIETIEAIREL
KKRHDVQTTLGLSNISFGLNARQVLNSVFLHECQEAGLDSAIVHASKILPMNRIPEELVYDRRREDYDPLQELMRLFEGVK-EDRLAELAGLP---LFER
LAQRIVDGERNGLDADLDEAMTQKPPL-QIINEHLLAGMKTVGELFGSGQMQLPFVLQSAEVMKAAVAYLEPHMERDDD---KGRIVLATVKGDVHDIGK
NLVDIILSNNGYEVVNIGIKQPIATILEVAEDKSADVVGMSGLLVKSTANSA-SVGMPPNADVYPAAAVSCAAAAAVATVARNG----------------
---
>tr|D1AP89|D1AP89_SEBTE Homocysteine S-methyltransferase OX=526218 OS=Sebaldella termitidis (strain ATCC 33386 / NCTC 11300). GN= PE=4 SV=1
-MGIREKLGK-EILFFDGAM---LQK----------DLNIDNPEIIEEIHRLYAKSGADIITTNTFGANRLKLE-HYSQEEIIKSG-SIAKKAN--DGYV
ALDIGPLGQ----LGVLPFEEAYEIFKEQIILGEKYGADIIIIETMVDIYEA---ILAAKENS-LPVICTVTFEDKRMLTGTSILGAVTILESLGVDALG
VNCSLGPKELIPIVDELLQYSKT-VIVQP--GLPK-MIGGNTVFDLSAEEYSSIMEDFVHKGISIIGGCCGTDERFIKSIHDKLIDFSPV-PRKI-K--S
-IATATKCVDLDEGIK--VIGERINPTGKKKLKEALINNNMEYILREAVTQKEKGADILDVNVG---INESEVITGVVKEIQSIIDLPLQIDSSDAGAIE
AALRIYNGKAVINSVNGK-EIMDTIFKI-RKYGACVVGL-LDENGIPSSAEERFKIAEKIVNT-EKYGIPKENLLIDCLVLTASAQQKE-SETLKAITMV
REKLGVKTVLGVSNVSFGLP-RALLNRTFLTMALHSGLTTPIL-PQSEEMMHII----VLTNQDKDSA-----------------------------DLE
LPDIIRLGLKEE-KSKIYSLLKE----MYIIDNYLIPVLDTIGIKFEKGEIFLPQLIQTAET-KYFFEILKG-IKE---FVNKGDIILATVKGDIHDIGK
NIVKIVLENYGYNIIDLGKDVPVEKVVNTAKEKNIQLIGLSALMTTTVKSMEETIKALRTSNIKCKVFVGGAVLTQEYAD--------EDAQESV-----
---
>tr|A5UPF4|A5UPF4_ROSS1 Methionine synthase (B12-dependent) OX=357808 OS=Roseiflexus sp. (strain RS-1). GN= PE=3 SV=1
---YLEALRE-RVLIYDGAMGTSIDTFHLTAGGARDYLVMTRPDVIEQIHTSFLEAGADVLETCTFQSTRIRLEEGLQTHAINVAAARLARRVADAPRYV
AGSMGPTGKLPSSLSDITFDQLSDIFYEQAVALIEGGVDVLLVETSVDILEVKAALDGIRRARDVAVQAQVFLDSGKMLLGTEVPALVATLEAMPVDVIG
LNCSTGPEHMREAIRYMTRHSRKPISCIPNAGLPIE-VNGETVYPMEPEPFARILGEYVEYGVAVVGGCCGTRPAHIRRLRQVV-GAAPKVRDI--EY-P
SVSSGVRAAALRQEGTLTIIGERVNTLGSRKVKRLLLNDDYDGVLEVAREQVDSGSHILDVCVAMTERDEREMMVRLLKKLTMNIELPLAIDTTEADVLN
AALAIYPGRAIVNSVSLERDKIDRTMPLVARYGAATIAMTIDEEGMAHTAERKLAIARRIAQIAQEYGVPPEALIFDVLTFPITTGQPEAIETIEGIRLV
KQHIGCFTTLGVSNLSFGVAARAALNSVFLKHAVDAGLDTAIINPAHVMPYAEIPCEDLIFDRDQALARFIQFFEGSAAKT----ERVDPTEG-MTAAQR
VHWKIVHRKKEGIEQDIDTVIRNS-AAVDVLNTVLLPAMKEVGDLFGAGQLILPFVLQSAEVMKKAVAHLEQYLEKLE---GKGKIVLATVYGDVHDIGK
NLVHTILANNGYTVYDLGKQVPINTIIEKAVEVNADAIGLSALLVSTSKQMPLCVQELHRRGLKFPVLVGGAAINKQYVDDEPGVFYCKDAFEGLETVDA
LV-
>tr|D8FYY1|D8FYY1_9CYAN Methionine synthase (B12-dependent) OX=272129 OS=Oscillatoria sp. PCC 6506. GN=OSCI_2110007 PE=3 SV=1
---RLHHPSR-PVIVFDGAMGTNLQFQNLTAGGCNEYLIYTNPEAVAKVHRGFLEAGADVIETDTFGASSFVLAENLEAYNLNKAAATLAKGLAIEPRFV
AGSIGPGTKLPT-LGHIDFDTLKIAFAEQAEGLFDGGVDLLIVETCQDVLQIKAALSAIEEVTRLPIMVSVTMETGTMLVGSDISAVLTILQPFPIDILG
LNCATGPDRMAEHIKYLSQYSPFVVSCIPNAGLPEN-VGGHAHYKLTPMELRMALMHFVDLGVQVIGGCCGTRYDHIQQLAEISTTLTPKVR--ETTWQP
AAASIYSAQPYDQDNSFLIVGERLNASGSKKCRDLLNAEDWDGLISMGREQVREGAHILDVNVDYVGRDGVRDMREVVSRLVTNATLPLMLDSTEWEKME
AGLKAAGGKCLLNSTNYEEPRFYKVLELAKTYGAGIVIGTIDEDGMARSANKKFEIASRAYHAAIEYGIPAYDIFFDPLALPISTGIEEGKSTIEAIRRI
RQELGCHVILGVSNISFGLNARQVLNSMFLHEAMQAGMDSAIVSPNKILPLAKIECRKLIYDRRDPLGELTNAFEGATT-------KRDRSDL-LPLEER
LKRHIIDGERIGLEEVLTTALEQ-YPPLEIINTFLLDGMKVVGELFGSGQMQLPFVLQSAETMKAAVAFLQPYMEKSESDNAKGTFIIATVKGDVHDIGK
NLVDIILSNNGYRVINLGIKQPVDNIIEAYEQHKADCIAMSGLLVKSTAFMKENLETFNQRGITVPVILGGAALTPKFVHEKGKVIYGKDAFSDLHFMDK
LM-
>tr|H8E3X7|H8E3X7_9MICO Methionine synthase OX=1160710 OS=Microbacterium laevaniformans OR221. GN=OR221_1557 PE=3 SV=1
---LLDTLSE-RVVIADGAMGTMLQRHDLQIGGCNEILNVTRPDVVGAIHDAYFAVGVDAVETNTFGANWSNLSDGIRITELAAAGARIARERAEAMRWV
LGSMGPGTKLPS-LGHTTYAHLKETFALQAEGLIDGGADAFLVETSQDLLQTKAAINGCKQAIRLPIFVEVTVETGAMLMGSEIGAALTALEPLGVDAIG
LNCATGPAEMSEHLRHLSKHSSVTIACMPNAGLPVL-TADGAHYPLTPAELATAHEQFVEFGIGLIGGCCGTTPEHLAAVVERVRDTESAPVSRRIETEP
GVASLYQHVPFRQDASYLAIGERTNANGSKAFREAMLEGRWEDCVEIARGQIRVGAHLLDVCVDYVGRDGVDDIREVVSRFASASTLPLVIDSTEPAVIQ
AGLELIGGRPVVNSVNYEDSRFGRIMPLVKEHGTAVIALTIDEQGQARTAEDKLRIASRLVDELVAWGMRVEDIIVDCLTFPIATGQEEGIETIEAIRGL
VAKYGINTTLGVSNVSFGLNARSVLNSVFLHEATQAGLTSGIIDAAKIVPLASLPALDLVWDRRDPLATMLDLFAGVDTAA----LRDQRAEAALPVGER
LERRIIDGELKGLEADLDLARAGDASPLQIINDHLLEGMKVVGERFGSGQMQLPFVLQSAEVMKTAVALLEPNMEKTD-EAGKGTIVLATVRGDVHDIGK
NLVDIILTNNGYTVINLGIKQPIADIIAAAEEHDADVIGMSGLLVKSTVVMKENLEELMARGLRWPVILGGAALTRAYVEQDGEVRYAKDAFEGLALMEP
LV-
>tr|K8GL67|K8GL67_9CYAN Methionine synthase (B12-dependent) OX=864702 OS=Oscillatoriales cyanobacterium JSC-12. GN=OsccyDRAFT_3018 PE=4 SV=1
---RLHHPDR-PVIVFDGAMGTNLQVQNLTAGGCNEYLIFTKPEAVAKVHRDFLAAGADVIETNTFGATSIVLAENLQAYELNKAAAELAKQVTAEPRFV
AGSIGPTTKLPT-LGHIDYDTMKTSFAEQAEGLWDGGVDLFIVETCQDVLQIKAALNGIEDVGRRPLMVSVTMEQGTMLVGSDVAAMLTILEPYPIDILG
LNCATGPDRMAEHIKYLSQHSPFVISCIPNAGIPEN-IGGHAHYKLTPIELRMALMRFVDLGVQVIGGCCGTRPDHIYQLAEIAETLKPKERQPSLGYIP
SAASIYTTQPYDQDNSFLIVGERLNASGSKKVRELLNAEDWDGLVAVARSQVREGAHILDVNVDYVGRDGERDMHELVSRLVTNVNLPLMLDSTEWEKME
AGLKVAGGKCILNSTNYEEPRFLKVLELAKRYGAGVVVGTIDEDGMARTAEKKFAIAQRAYRQALEFGIPAHELFFDTLALPISTGIEEGKATIEAIRMI
RDNLGCHILLGVSNISFGLSARIVLNSMFLHEAVRAGMDGAIVSAAKILPLAKIDCRQLIYDQRDPLTQLTTLFEGVST-------QEARSDA-LPIEER
LKRHIIDGERIGLEEALTEALKL-YKPLDIINTFLLDGMKVVGDLFGSGQMQLPFVLQSAETMKAAVAHLEPFMEKSETSSSKGVFLIATVKGDVHDIGK
NLVDIILTNNGYRVINLGIKQPVENIIEAYQEHQADCIAMSGLLVKSTAFMKENLEVFNERGITVPVILGGAALTPKFVYEKGQVIYGKDAFADLHFMDK
LM-
>tr|C4LIL8|C4LIL8_CORK4 5-methyltetrahydrofolate--homocysteinemethyltransferase OX=645127 OS=Corynebacterium kroppenstedtii (strain DSM 44385 / CCUG 35717). GN= PE=3 SV=1
---FLQALHD-RVLIGDGAMGTQLQAIDLDLGGCNEILNITRPDILADIHRRYFEAGADAVETNTFGCNLPNFADGIRIEEIAYAGTQIARSVADDKRFV
LGSLGPGTKLPT-LGNAPFSDLRDAYTEAAHGLVRGGADAILIETAQDLLQVKAAVHGVQQATTLPIMCHVTVETGTMLLGSEIGAALTALERLGIDVIG
MNCATGPDEMNEHLRYLSAHAPMPVSVMPNAGLPEL-GANGAVYPLTPDELAAASVHFVDYGLSMVGGCCGTTPEHITAVRDAVIGSPRPARHH--DFDD
NVSSLYSTVPLTQDTGITMIGERTNSNGSKAFRTAMLEGDWNKCLDIAKAQTRDGAHMIDLCVDYVGRDGTQDMAELASRLATNSTLPIMLDSTEPDVIR
MGLEHLGGRCAVNSVNFEDSRYDRIMTLVKKHGAAVVALTIDEEGQARTAEKKVEIAERLIADITRWGLRESDIIVDCLTFPISTGQVEGIETINAIREI
TSRHDIHTTLGLSNISFGLNARQVLNSVFLNECIEAGLDTAIAHSSKIVPMNRIDALDMVYDRRDPLQTFMELFQGVSAAD----AKDARAAQALPLFKR
LAQRIIDGEKNGLEADLDLARDEK-DPLEIINQDLLAGMKVVGDLFGSGQMQLPFVLQSAETMKAAVSHLEQFMEATD-DSAKGKIILATVKGDVHDIGK
NLVDIILSNNGYDVVNLGIKQPISNILHAASEHQADVIGMSGLLVKSTVVMKDNLLEMNSAG-NYPVLLGGAALTRTYVENQGDVHYARDAFEGLNLMDQ
IM-
>tr|F8E275|F8E275_CORRG 5-methyltetrahydrofolate-homocysteinemethyltransferase OX=662755 OS=Corynebacterium resistens (strain DSM 45100 / JCM 12819 / GTC 2026). GN= PE=3 SV=1
---FLNALRE-RVLIGDGAMGTQLQAVELDLGGCNEILNETRPDVLRDIHRAYFEAGADLVETNTFGCNLPNLADDIRIEDLAYRGAKIAREVADEPSFV
VGSMGPGTKLPS-LGHAPYAALRDAYVESARGLIRGGCDAILIETCQDLLQVKAAVLGAKQATRVPIVVHVTVETGTMLLGSEVGAALTALEPLGIDMIG
MNCATGPDEMSEHLRYLSNNTSLPVSVMPNAGLPVL-GANGAEYPLTAPELGVALRGFVDYGLSMVGGCCGTTPEHITAVREAVLGTQQAKRTV--NVNN
NVASLYQAVPLTQDTGITMIGQRTNANGSKAFREAMLAGDLEKCLEIAKDQVRDGAHMVDLCIDYVGRDGTEDMARLAALLATNSTLPIMIDSTEPDVIR
VGLEHLGGRSAVNSVNFEDSRYQRIMRLVKQHGAAVVALTIDEEGQARTAEKKVEIAERLIADITSWGVPEEDIIVDCLTFPISTGQEEGIETINAIREL
KKRHAVHTTLGLSNISFGLNARQVLNSVFLNECIEAGLDTAIAHSSKILPMNRIDALDMVYDRRDPLQTFMQLFEGVSAAS----AKDARAAAAMPLFER
LAQRIIDGDRNGLTDDLDEAMKEK-DPVAIINEDLLAGMKTVGDLFGSGEMQLPFVLQSAETMKAAVANLEPHMESEA-GSGKGKMVIATVKGDVHDIGK
NLVDIILSNNGYDVVNIGIKQPISAILEAAEENNADVIGMSGLLVKSTVVMKENLEELNRLG-HYPVMLGGAALTRPYVEDDGDVYYSKDAFEALTVLDG
IM-
>tr|K9P4X1|K9P4X1_9CHRO 5-methyltetrahydrofolate--homocysteine methyltransferase OX=292564 OS=Cyanobium gracile PCC 6307. GN=Cyagr_0565 PE=4 SV=1
---WLHGPTR-PVLVFDGATGTSLQEMNLTAGGCNENLVFTRPDAVQAVHRQFLEVGCDVIETDTFGAASIVLAEGLQAFAINRRAAELAREMAAAPRFV
AGSMGPTTKLPT-LGHIDFDTMKASFREQAAGLIAGDVDLFIVETCQDVLQIKAALQGIEEAERRPLMVSVTMETGTMLVGSDIAAVVAILEPFPIDVLG
LNCATGPEQMKEHIRYLSQHSPFVVSCIPNAGLPEN-IGGVAHYRLTPTEMRMQLMHFVDLGVQVIGGCCGTTPAHIGALAELASGLKPAPREVRLHYEP
AVASIYGVTPYFQDNSFLIIGERLNASGSKKVRELLNAEDWDGLVAVARGQVKENAHVLDVNVDYVGRNGVKDMNDLVSRLVTNVNLPLMLDSTEWQKME
AGLKVAGGKCILNSTNYEDERFFKVLELARDYGAGVVVGTIDEEGMARTAERKFAIAQRAYRDALEFGLPAHEIFYDPLALPISTGIEEAAATIEAIRRI
RQDLGVHVVLGVSNVSFGLSARIVLNSVFLHDCCAAGMDAAIVSPAKILPLAKISCRDLIHDRRDPLTLLTSEFEGVSA-------REARAGADLPLEER
LKQHIIDGERIGLEAALQEALAE-HPPLKIINTFLLDGMKVVGELFGSGQMQLPFVLQSAETMKAAVAFLEPHMERQEGSSSKGKFLIATVKGDVHDIGK
NLVDIILTNNGYEVVNLGIKQSVDAIVEAQRQHRADCIAMSGLLVKSTAFMKDNLETFNEVGISVPVILGGAALTPRFVNGRGQVIYGRDAFADLRFMDA
LM-
>tr|Q111X5|Q111X5_TRIEI Methionine synthase (B12-dependent) OX=203124 OS=Trichodesmium erythraeum (strain IMS101). GN= PE=3 SV=1
---RLQSPDR-PVLIFDGAMGTNIQSQNLTAGGCNEYLVVTKPEAVAKVHRDFLAAGADVVETDSFGSSPLVLAENLRAYELSRKAAELARSCADEPRFV
AGSIGPGTKLPT-LGHITYDELKASFMVQAEGLYDGGADLFIVETCQDVLQIKAALSAFEAVSRLPLMVSVTMEQGTMLVGTDISGVLAILEPFPIDILG
LNCATGPNLMTSHIKYLSENSPFPISCIPNAGLPEN-IGGQAHYKMTPLEFKTSMSEFIQYGVQIVGGCCGTRPAHIQALADAVEETPLKERSVRLSYTP
AAASIYSAQTYEQDNSFLIVGERLNASGSKKVRKLLNEDDWDGLLAIAKSQVKEGAHMLDVNVDYVGRDGERDMRELVSRLVTNTTLPLMLDSTEWTKME
AGLKVAGGKCLLNSTNYEEERFFKVLELAKEYGAGVVIGCIDEEGMARTAKKKFEIAQRAYKDALKFGIPPHEIFYDTLALPISTGIEEAKATIESIRLI
RENLGVHFMLGVSNISFGLSTRITLNSIFLNEAMKAGMDGAIVSAAKILPLSKIDCCDLIYDNRDPLTKLTEIFAGVSA-------KDARSLD-LPIDQR
LKQHIIDGERIGLEDALKVALDAGHKALEIINTFLLDGMKVVGELFGSGQMQLPFVLQSAETMKSAVAFLEPYMEKGEDDRGKGKFLIATVKGDVHDIGK
NLVDIILTNNGYKVINLGIKQAIEAIVEAYEQHKPDCIAMSGLLVKSTAFMKENLAAFNAKGITVPVILGGAALTPKFVYGQGQVIYGKDAFADLTFMDR
LM-
>tr|D7BGK6|D7BGK6_MEISD Methionine synthase OX=526227 OS=silvanus). GN= PE=3 SV=1
---YLRALSE-RVLIYDGAMGTEIFKYDLSAAGCPEMLNRTRPDVIEAIHKSYLEAGADVIETNTFGAFPHVLVEGLEAYELAFAGAHLARRVADEPRFV
AGSMGPGTKLIS-LGQISWEGLFESYRVCAQGLLDGGVDLILIETCQDILQVRCAVLAARRAREVPIQVQVTMETGTMLVGTDDAAALTVLEALPIDVVG
FNCATGPDLMDTHVRFFCENATRWVSCLPNAGLPRN-EGGRVVYDLTPAELARWQQKFVEYGLNVVGGCCGTGPEHIRALAQALRRQPKANRQG--QFPA
QVASLYQAIPLKQDTGILIVGERTNATGSKKFRELLFAEDWEGMLELAQEQVAEGAHVLDVSVAWTGRDEVRDMREVVKRFATSVQIPIMIDSTQTDVMQ
AALEHLGGRAILNSVNLELEKFDRVASLARQHGAALVALTIDEDGMAKTPERKVEIALRMYERLTVHGIPGSSILFDLLTFPITQGDEDAMWTIEGIRRV
RELLEVGFILGISNVSFGLSARVVLNSVFLDECIKAGLTAAILNAGKIRPINQIPALDLIYDRRDPLFAFVDYFAKNKVER----SS--AAPTGLSVEER
LKKRIIEGRKVGLEADLESALQAGYTPVSLINEVLLEGMKVVGDLFGAGKMQLPFVLQAAETMKAAVRYLEPKMDREG-V-HKGTMVLATVKGDVHDIGK
NLVDIILSNNGYKVVNLGIKKPIEEILAAVEEHRPQAVGMSGLLVKSTVVMKENLEYMRERG-RIPVILGGAALNRHYVENTTGVYYASDAFDGLQLMDE
LC-
>tr|K9FJ28|K9FJ28_9CYAN Methionine synthase (B12-dependent) OX=102129 OS=Leptolyngbya sp. PCC 7375. GN=Lepto7375DRAFT_5108 PE=4 SV=1
---RLHSPSR-PVLVFDGAMGTNLQVQELTAGGCNEYLVVTKPEAVAKVHRDFLASGADVIETDTFGGSTFVLAEGLKAYDLNKVAAELAKGCTAEPRFV
AGSMGPGTKLPT-LGHITYDELLEAFTVQAEGLYDGGVDLFIVETCQDVLQIKAALNAIEAVARLPLMVSVTMETGTMLVGSDITAVVSILEPYPIDILG
LNCATGPDLMTEHIKYLSETSPFVVSCVPNAGLPEN-IGGHAHYKLTPMELRMALHRFVDFGVQVIGGCCGTRPDHIAALAEISQELSPKDRDI--RFSP
AAASIYGAQPYEQDNSFLIVGERLNASGSRKVRELLNEDDWDGLIAIAKRQVKEGAHILDVNVDYVGRNGEADMHEIVSRLVTNVTLPLMLDSTEWTKME
AGLKVAGGKCILNSTNYEDERFFKVLELAKTYGAGVVVGCIDEDGMARTAEQKSQIAQRAYHDALEYGLPPHELFFDTLALPISTGIEEAKATIEAIKQI
KETLGVHFMLGVSNISFGLNARITLNSVFLHEAMQVGMDGAIVSAAKILPLIKIDCKDLIYDNRDPLGDLTTLFEGVTT-------KDARSAD-LPIEER
LKQHIIDGERIGLEEALQIALDTPYEPLQIINTFLLDGMKVVGELFGSGQMQLPFVLQSAQTMKAAVAFLEPLMEKEDGDRGKGKFLIATVRGDVHDIGK
NLVDIILTNNGYKVINLGIKQTIDAIVAAYEEHQPDCIAMSGLLVKSTAFMKENLAVFNEKKISAPVILGGAALTPKFVYGNGQVIYGKDAFADLTFMDR
LM-
>tr|Q8NQD1|Q8NQD1_CORGL Methionine synthase I, cobalamin-binding domain OX=196627 OS=LMG 3730 / NCIMB 10025). GN= PE=3 SV=1
---FLDALAN-HVLIGDGAMGTQLQGFDLDVDGCNEILNDTRPDVLRQIHRAYFEAGADLVETNTFGCNLPNLADDIRCRELAYKGTAVAREVADERRFV
VGSLGPGTKLPS-LGHAPYADLRGHYKEAALGIIDGGGDAFLIETAQDLLQVKAAVHGVQDATFLPIICHVTVETGTMLMGSEIGAALTALQPLGIDMIG
LNCATGPDEMSEHLRYLSKHADIPVSVMPNAGLPVL-GKNGAEYPLEAEDLAQALAGFVEYGLSMVGGCCGTTPEHIRAVRDAVVGVPQASREV--EKED
SVASLYTSVPLSQETGISMIGERTNSNGSKAFREAMLSGDWEKCVDIAKQQTRDGAHMLDLCVDYVGRDGTADMATLAALLATSSTLPIMIDSTEPEVIR
TGLEHLGGRSIVNSVNFEDSRYQRIMKLVKQHGAAVVALTIDEEGQARTAEHKVRIAKRLIDDITSYGLDIKDIVVDCLTFPISTGQEEGIETIEAIREL
KKLYEIHTTLGLSNISFGLNARQVLNSVFLNECIEAGLDSAIAHSSKILPMNRIDALDMVYDRRDPLQEFMQLFEGVSAAD----AKDARAQAAMPLFER
LAQRIIDGDKNGLEDDLEAGMKEK-SPIAIINEDLLNGMKTVGELFGSGQMQLPFVLQSAETMKTAVAYLEPFMEEEA-EATKGKIVVATVKGDVHDIGK
NLVDIILSNNGYDVVNLGIKQPLSAMLEAAEEHKADVIGMSGLLVKSTVVMKENLEEMNNAG-NYPVILGGAALTRTYVENTGEVYYARDAFEGLRLMDE
VM-
>tr|A3YZM5|A3YZM5_9SYNE Putative methionine synthase OX=69042 OS=Synechococcus sp. WH 5701. GN=WH5701_13030 PE=3 SV=1
---HLHGPGR-PVVVFDGATGTSLQQMDLSAGGCNENLVFTRPDAVQAVHAQFLEAGCDVIETDTFGAASIVLAEGLQAFALNQRAAELAREMADRPRFV
AGSMGPTTKLPT-LGHIDFDTMKASFREQAAGLLAGDVDLFIVETCQDVLQIKAALQGLEEAERRPLMVSVTMETGTMLVGSDIAAVVSILEPFAIDVLG
LNCATGPEQMKEHIRYLSEHSPFVISCIPNAGLPEN-VGGVAHYRLTPLELRLQLLHFVDLGVQVIGGCCGTTPSHIAALAELAVDLHPSPRPVRLQWEP
AAASIYGVTPYHQDNSFLIIGERLNASGSRKVRDLLNAEDWDGLVALARGQIKENAHVLDVNVDYVGRDGEKDMHDLVSRLVTNVNLPLMLDSTEWQKME
AGLKVAGGKCILNSTNYEDERFFKVLELARRYGAGVVVGTIDEEGMARTAERKFAIAQRAYRDALEYGIPAHEIFYDPLALPISTGIEEAAATIEAIRLI
RENLGVHVVLGVSNVSFGLSARIVLNSVFLHECCEAGLDAAIVSPAKILPLAKITCRDLIEDRRDPLTVLTSLFEGVSA-------KEARAGADLPVEQR
LRQHIIDGERIGLEPALQEALAS-YPPLQIINTFLLDGMKVVGELFGSGQMQLPFVLQSAETMKAAVAFLEPHMEKVDGSSAKAKFLIATVKGDVHDIGK
NLVDIILTNNGYEVINLGIKQGVEAIIEAQHLHQADCIAMSGLLVKSTAFMKDNLQAFNEAGITAPVILGGAALTPRFVQKNGQVIYGRDAFADLRFMDA
LS-
>tr|Q2JS51|Q2JS51_SYNJA Methionine synthase OX=321327 OS=Yellowstone A-Prime). GN= PE=3 SV=1
---HL---QE-RVIVFDGAMGSSLQAQNLTAGGCNEILVLSKPEAVERVHRGFLEVGADVIETDTFGATSIVLAEGIKAYELNVAAARLAKRLAAEPRFV
AGSIGPTTKLPT-LGHIGFDEMRASYAEQVRGLIDGGVDLLIIETCQDILQTKAALVAVQQEIRLPLVVSLTFEQGTMLVGTEIGAALAILEPYPIDVLG
LNCATGPDKMAEHIRYLSRHSPFPISCIPNAGLPEN-IGGKAHYKLTPEQLRFHLEHFVDLGVAVVGGCCGTRPGHIAALVEAVRGLRPKRR----SVEQ
AAASIYAPQPYLQENSFLIIGERLNASGSKKMRELLNAEDWDGLVALAREQVREGSHILDVNVDYVGRDGVRDMRELVSRLVTQIPIPLMLDSTDWQKME
AGLKVAGGKCLLNSTNYEEERFFKVLELAKTYGAGVVIGTIDEEGMARTAEKKFQIAERAYRQAVEYGIPPYEIFFDPLALPISTGIEEGAATLEAIRRI
RQAFEAHILLGISNISFGLSARVVLNSVFLHECRQAGLDAAIVSAAKILPLSKIPCRDLIWDRRDPLARLTELFAGVSG-------QELRAGAKLPLEER
LRRHIIDGERIGLEETLAEALQK-YPPLEIINTFLLDGMKEVGELFGAGKMQLPFVLQSAETMKAAVKYLEPFMEK--GEVCKGTFLIATVKGDVHDIGK
NLVDIILTNNGYKVINLGIKQPVENIIEAYEKYKPDCIAMSGLLVKSTAFMKENLEVFNERGITVPVILGGAALTRRFVEEKGQVIYGRDAFADLHFMDR
LM-
>tr|E2MWQ9|E2MWQ9_9CORY Methionine synthase OX=553204 OS=Corynebacterium amycolatum SK46. GN= PE=3 SV=1
---FLTALHS-RVLIGDGAMGTQLQSFDLDVGGCNEILNDTRPDIIETIHRRYFEAGADLVETNTFGCNFPNLADDIRIQELAHKGTAIARKVADERRFV
LGSLGPGTKLPS-LGHAPYAQLRDAYTEAGLGMISGGADAFLIETCQDLLQVKAAVNGVKAAKKIPIVVHVTVETGTMLMGSEIGAALAALQPLGIDMIG
LNCATGPDEMSEHLRYLSSFASIPVSVMPNAGLPVL-GKNGATYPLTAPELATALRGFVEFGLSMVGGCCGTTPEHVSAVRDAITGTGQAARPS--TDPD
EVASLYSATPLTQTTGITMIGERTNANGSKAFREAMLAGDWEKCLNTARGQVTDGAHMIDLCVDYVGRDGRDDMATLASQIATSVTLPVMLDSTEPEVLK
TGLEHLGGRCAVNSVNFEDSRYQRIMRQVVEHGAAVVALTIDEEGQARTKDKKIEIAERLIADITTWGLREQDIIVDCLTFPISTGQEEGIETIEAIREL
KRRHNVHTTLGLSNISFGLNARQVLNSVFLNECIEAGLDSAIAHSSKILPMNKIDALDMVYDRRDPLQVFMELFEGVSAAD----AKDARAQAAMPLFDR
LAQRIIDGERTGIEADLDESMKEK-EPLAIVNEDLLRGMQTVGDLFGSGQMQLPFVLQSAETMKAAVGYLEGFMDAE--DATKGSIVLATVKGDVHDIGK
NLVEIILSNNGYTVHNLGIKQPIATILSAAKELDVDAIGMSGLLVKSTVVMKDNLLEINSAGDRFPVLLGGAALTRSYVEDHGDVYYGRDAFEGLRIMDE
LM-
>tr|A0K132|A0K132_ARTS2 Methionine synthase (B12-dependent) OX=290399 OS=Arthrobacter sp. (strain FB24). GN= PE=3 SV=1
---LLDAVNT-RVVIADGAMGTMLQGRELSLGGCNEILNDTRPDVLADIHDAYFATGIDAVETNTFGANWSNLSDGIRIEELARKGAAIARERAEAMRWV
LGSMGPGTKLPS-LGHTTYDYLKQTFALQAEGLIDGGADAFLIETSQDLLQTKAAVNGCKQAIRLPIFVEVTVETGTMLMGSEIGAALTALEPLGVDAIG
LNCATGPDEMSEHLRHLSKQSSVAIACMPNAGLPVL-GPNGAHYPLSPSELATAHEQFVEFGLGLVGGCCGTTPEHMAAVVERLRGADGSRVPT--EREA
GIASLYHHVPFDQESAYLAIGERTNANGSKAFRQAMLEERWDDCVDIAREQVRVGAHLLDVCIDYVGRDGVADIKEIVSRFASASTLPLVIDSTEPPVLQ
AGLELIGGRPVVNSVNYEDSRFARIMPLVKEHGTAVIALTIDEQGQARTTEGKVAIASRLVDALVEWGMRVEDIIVDALTFPVATGQEEGIETIEAIRQI
TTKYGINTTLGVSNVSFGLNARVVLNSVFLHEAVQAGLSSGIIDAAKIVPLASLPALDLVYDRRDPLAIMLDLFAGVDTAA----LKDQRAEAALPTGER
LQRRIIDGEGKGLEADLDLARSEG-TPLGIINDQLLEGMKVVGERFGAGEMQLPFVLQSAEVMKNAVALLEPHMEKSD-SSGKGTMVIATVRGDVHDIGK
NLVDIILTNNGYKVVNIGIKQGIAEIMAAAEEHNADVIGMSGLLVKSTVVMKENLAELQSRGLKWPIILGGAALTRAYVEQEGTVRYAKDAFEGLALMEP
LV-
>tr|D3PR18|D3PR18_MEIRD Methionine synthase OX=504728 OS=(Thermus ruber). GN= PE=3 SV=1
---YLKTLSE-RVLVYDGAMGTEIFKYNLGDGGCPEILNRTRPDVIAAIHRSYLEAGADVIETNSFGSMPHVLAEGLEAEDLAYAAAQIARSEADKPRFV
AGSLGPGTKLIS-LGQIGWKEMFESYRTAARGLIRGGVDLLIIETCQDVLQVRCAVLASRQAREVPLQVQVTFETGTLLVGSDDGAALTVLESLPVDVVG
INCAVGPDLMDSHIRHFCQHSTRWVACLPNAGLPRN-EGGRAVFDLTPAELARWQLKFVEYGLNVVGGCCGTGPEHIRALVEALHTPPRSSQQA--QTPS
QVASLYQSVPLRQDTGILIVGERTNATGSKKFRELLFAGDFDGMEALANEQVAEGAHVLDVSVAWTGRDEVRDMREVLKRFATSVPIPIMVDTTQPEVME
EALKHLGGRAILNSINLELEKFDRVAALAKRHGAALVALTIDEDGMAKTVERKVEIALRIYERLTVHGIAGESILFDLLTFPITQGDEDALWTIEGIRQL
RQQLEVGFILGISNVSFGLSARVVLNSVFLDECIRAGLTAAILNAGKILPINQIPALDLIYDRRDPLFAYVDYFAKNKVDK----AQ--ARPAGLELEER
LKKRIIEGRKVGLEADLEQAL-GKYSPVEIINQILLEGMKVVGDLFGAGKMQLPFVLQAAETMKAAVRYLEPRMEKEG-V-HKGTMVIATVKGDVHDIGK
NLVDIILSNNGYKVINLGIKKPIEEILAAVEEHRPDVVGMSGLLVKSTVVMKENLEYMAARG-SLPVVLGGAALNRHYVENTTGVYYASDAFDGLQLMEE
LT-
>tr|Q7V7L3|Q7V7L3_PROMM Putative methionine synthase OX=74547 OS=Prochlorococcus marinus (strain MIT 9313). GN= PE=3 SV=1
---RLHSSER-PVLVFDGATGTSLQKQNLSAGGCNENLVVTRPDAVKEVHRQFLESGCDVIETNSFGAASIVLAEGLQAFELNRQAAQLAKSMAVQPRFV
AGSIGPTTKLPT-LGHIAFDTMRDSFQEQAEGLLAGDVDLFIVETCQDVLQIKAALQGIECAERRPIMVSVTMETGTMLLGSDIASVVTILEPFPIDILG
LNCATGPEQMKEHIRYLSEHSPFTISCIPNAGLPEN-IGGVAHYRLKPLELKMQLMHFVDLGVQVIGGCCGTTPEHTSALAELAKEMRAAQRPCRFGYEP
SAASIYGITPYHQDNSFLIIGERLNASGSKKVRELLNSEDWDGLVGLARGQLKENAHILDVNVDYVGRDGEKDMNQLVSRLVTNINLPLMLDSTEWQKME
AGLKVAGGKCILNSTNYEEERFFKVLDLAKKYGAGLVIGTIDENGMARTAMQKVAIAKRAYRDATEYGIPAHEIFYDPLALPISTGIEEGLETIEAIRVI
REELAVHVVLGVSNVSFGLSARITLNSVFLHDCTDAGMDAAIVSPAKILPLNKVSCRDLINDHRDPLTELTSLFEGVSA-------KEARAGADLPVEDR
LKQHIIDGERIGLNEALDEGLES-YKPLQLVNTFLLDGMKVVGELFGSGKMQLPFVLQSAQTMKAAVAYLEPYMEKSAGKSSKAKFLIATVKGDVHDIGK
NLVDIILTNNGYEVINLGIKQDSASIINAQMTHQADCIAMSGLLVKSTAFMKSNLQEFNDSGITVPVILGGAALTPRFVNHKGKLIYGKDAFTDLRFMDA
YV-
>tr|K9VV74|K9VV74_9CYAN Methionine synthase (B12-dependent) OX=1173022 OS=Crinalium epipsammum PCC 9333. GN=Cri9333_0042 PE=4 SV=1
---RLHSPEH-PVIVFDGAMGTNLQTQNLTAGGCNEYLIHTNPEAVAKVHRDFLAVGADVIETDTFGATSIVLAENLQTYYLNKAAAELAKRVAAEPRFV
AGSIGPTTKLPT-LGHIDFDTMAANVAEQADALYDGGVDLFLVETCQDVLQIKAALNGLEEVERIPIMVSVTMETGTMLVGSDISAVVSILEPYQIDILG
LNCATGPDRMAEHIKYLSANSPFVVSCIPNAGLPEN-VGGQAHYRLTPMELRMALMHFVDLGVQIIGGCCGTRPGHIEQLAEISKSLKPKERHPQLQYTP
AAASIYSAQPYEQDNSFLIVGERLNASGSKKCRDLLNAEDWDGLVSLAREQVREGAHILDVNVDYVGRDGVRDMRELVSRLVTNVTLPLMLDSTEWEKME
AGLKVAGGKCLLNSTNYEEPRFYKVLEIAKKYGAGIVVGTIDEDGMARTADRKFAIAQRAYRAAVEYGIPAHEIFFDPLALPISTGIEEGKATIDAIRRI
RQELKCHVILGVSNVSFGLNARQVLNSMFLNLAMEAGMDAAIVSPNKILPLAKIECRKLIFDERDPLGQLTDLFQGKTT-------KRDRTDN-LPVEER
LTRHIIDGERIGLEEQLAKALEK-YPPLEIINTFLLNGMKVVGELFGSGQMQLPFVLQSAETMKSAVAYLEPFMEKKDANNAKGTVIIATVKGDVHDIGK
NLVDIILSNNGYRVINLGIKQPVDNILDAYEQHKADCIAMSGLLVKSTAFMKDNLEVFNERGITVPVILGGAALTPKFVNEKGKVVYGKDAFSDLHFMDK
LM-
>tr|B8HR05|B8HR05_CYAP4 Methionine synthase OX=395961 OS=Cyanothece sp. (strain PCC 7425 / ATCC 29141). GN= PE=3 SV=1
---RLHHPDR-PVLVFDGAMGTNIQTQNLTAGGCNEYLVHTKPEAIAKVHRDFLAAGADVIETDTFGSSPLVLAEDLQSYYLSKTAAELAKQCAAEPRFV
AGSIGPGTKLPT-LGHINYDQLKAAFTVQAEGLFDGGVDLFIIETCQDVLQIKAALNAVEAVERRPLMVSVTMEQGTMLVGTDISGVLAILEPYPIDILG
LNCATGPDRMADHIKYLTENAPFVVSCIPNAGLPEN-IGGHAHYKLTPMELRLALHRFVDWGVQVIGGCCGTRPAHIQALAEIAQSLQPKARNV--RVGP
AAASIYTAQPYEQDNSFLIVGERLNASGSKKVRELLNADDWDGLIAIAKAQVKEGAHVLDVNVDYVGRNGERDMHELVSRLVTNITLPLMLDSTEWQKME
AGLKVAGGKCILNSTNYEPERFFKVLELAKTYGAGVVIGTIDEEGMARTAERKFQIAQRAYRDAVEFGLPPHELFFDTLALPISTGIEEGKATIEAIRRI
RAELGVHFMLGVSNISFGLSARITLNSMFLHEAMQVGMDGAIVSAAKILPLSKISCQDLIYDRRDPLTQLTTLFEGVSA-------KEARSSD-LPIEER
LKQHIIDGERIGLEAALKIALET-YKPLEIINTFLLDGMKVVGELFGSGQMQLPFVLQSAETMKAAVAFLEPLMDKVEGDSGKGKFLIATVKGDVHDIGK
NLVDIILTNNGYKVINLGIKQPVDAIIDAYTQHQPDCIAMSGLLVKSTAFMKENLEVFNQRGITVPVILGGAALTPKFVYENGQVIYGRDAFADLTFMDR
LM-
>tr|H0E7J4|H0E7J4_9ACTN 5-methyltetrahydrofolate--homocysteine methyltransferase OX=1097667 OS=Patulibacter sp. I11. GN=PAI11_27960 PE=3 SV=1
---YLAAVRE-GVVVFDGSMGALLEEKNLSERRAHEVLVLNRPDVIEELHTTMLDAGAVVLETDSFQASRLKLDEGLHTLEINVRAAEIARKAA--DRFV
AGSIGPTGFLPSSLGNILFPELVTVFEEQSRGLIQGGADLLIIETAQDILEVKAAIFGAREARRVPLQISVLLPGGKMLLGTDVAAVVTTLEALKVDVIG
LNCSTGPEDMRDAIRYLGENASVPVHCIPNAGIPQQGVNGETVFPEKPQPLADALGEFVDYGVAIVGGCCGTTPEHISAIAERV-ARKAGRTAN--AG-V
QVSSMIGAADLVQEPRPTIVGERVNSQGSRKAKELLLADDYDSLVTIAEGQVEGGAHVLDVCVALTERDEAEQMRQVVKKISLTQPAPIQIDSTEPDVIK
VALEQIPGRAIVNSVNLERDKMDVVVPLALEHGAAVIALTIDEIGMGKTVERKLEIAERIKQIACEHGLEPEALIFDLLTFTLTTGDEEAVQTIEAIRAI
GDRLGVKTSLGVSNVSFGVGARSVLNSVFLYHCVEAGLDLAMVNPAHIIPMGEIDAEDLVWNRRDALELFINHFEGPGEETA---EKADPTAE-MEPEEA
LHFRILKRKKDGVEADIDRAVEKL-GAVPVLNDVLLPAMKEVGDKFGAGELILPFVLQSAEVMKKAVKQLENYLERTA---DKGTVVLATVFGDVHDIGK
SLVNTILSNNGYTVVDLGKQVPVGTILEAAKEHDATAIGLSALLVSTSKQMPLAVQELHREGLKYPVLVGGAAINRNFPNGEGGVFYCKDAFEGLGVMDR
MV-
>tr|Q7U6U8|Q7U6U8_SYNPX Putative methionine synthase OX=84588 OS=Synechococcus sp. (strain WH8102). GN= PE=3 SV=1
---HLNGPER-PVLVFDGATGTSLQGLDLTAGGCNENLAVTKPEAVKAVHRQFLEVGCDVIETDTFGAASIVLAEGLKAFELNKRAAELAREMADEPRFV
AGSMGPTTKLPT-LGHIDFDTMRDSFREQAEGLIAGDVDLFIVETCQDVLQIKAALQGIEEAERRALMVSVTMETGTMLVGTDIAAVVSILEPFPIDILG
LNCATGPEQMKEHIRYLSEHSPFTVSCIPNAGLPEN-VGGVAHYRLTPVELKMQLMHFVDLGVQVIGGCCGTTPSHIGSLAELAAELKPALRSSRLNYEP
AAASIYGVTPYQQDNSFLIIGERLNASGSRKVRELLAEEDWDGLVSVARGQVKENAHVLDVNVDYVGRDGEQDMHQLVSRLVTNVNLPLMLDSTEWQKME
AGLKVAGGKCILNSTNYEDERFFKVLELARRYGAGVVVGTIDEDGMARTAEKKFAIAQRAYRDALEFGIPAHEIFYDPLALPISTGIEEGKATVDSIRMI
RENLGVHVVLGVSNVSFGLSARITLNSVFLHDCCEAGMDAAIVSPAKILPLIKITCRDLINDNRDPLTELTKLFEGVSA-------KEARAGADLPIEER
LKQHIIDGERIGLEPSLDEALQA-YPPLQIINTFLLDGMKVVGELFGSGQMQLPFVLQSAETMKSAVAYLEPHMETAEGSTSKGKFLIATVKGDVHDIGK
NLVDIILTNNGYEVVNLGIKQSCEAIVEAQHEHQADCIAMSGLLVKSTAFMKDNLKAFNDAGIDVPVILGGAALTPRFVQKNGKVIYGRDAFADLRFMDA
LM-
>tr|K6WR05|K6WR05_9MICO Methionine synthase OX=1184609 OS=Kineosphaera limosa NBRC 100340. GN= PE=4 SV=1
---LRSLLNR-RVIVADGAMGTMLQAADPSLNGCNEILNVTRPDIVRSVHAEYLQVGVDAIETNTFGANLANLGEDIRIYELAEAGARIAREVADEPRFV
LGSIGPGTKLPS-LLHAPYAVLRDAYEQCAIGLIDGGADALLVETSQDLLQAKAAIVGCKRAADLPIIASVTIETGTMLMGSEIGAALTALEPLGIDVIG
LNCATGPAEMSEHLRHLATHARVPISCLPNAGLPQL-GKDGAHYPLTPAELAAAHTQFVDYGLALVGGCCGTTPEHLKAVVEAVGGQEVAPRTP--VEEA
GVASLYTAVPFRQDASYLSIGERTNANGSKAFRVAMLEQRWDDCVEIAKDMTREGAHLLDVCVDYVGRDGAGDMSELVSRLATSSTLPLVLDSTEPAVVE
AGLERLGGRAVINSVNYEDSRFAKMTALATEHGAALVALTIDEEGQARTAEKKVAIASRLIDSLVEMGFRVEDIIVDALTFPIATGQEEGIETIEAIREI
TTKYGVQTTLGVSNVSFGLKARVVLNSVFLDEAAKAGLSSAIVNSAKILPVARIPALDLVWDRRDPLARMLELFEGVDSAS----LKASRAEEALPLGER
LQRRIIDGERNGLEADLDEALSGT-RALDIINDHLLAGMKVVGELFGSGKMQLPFVLQSAETMKAAVAHLEPTIEEQE-SAGKAKVLLATVKGDVHDIGK
NLVDIILSNNGYDVVNIGIKKTVNEIIDAATEHEVDAIGMSGLLVKSTVVMKDNLEEFNSRGLKWPVMLGGAALTRAYVEQDGHVRYARDAFEGLRLMDA
IA-
>tr|Q0IAG2|Q0IAG2_SYNS3 Methionine synthase OX=64471 OS=Synechococcus sp. (strain CC9311). GN= PE=3 SV=1
---RLHDPSR-PVLVFDGATGTSLQQMDLSAGGCNENLVVTRPDAVQSVHRQFLDAGCDVIETDTFGAASVVLAEGLKTFELNKRAAELAKEVAMEPRFV
AGSMGPTTKLPT-LGHISFDLLRDSYQEQAEGLIAGDVDLLIIETCQDVLQIKAALQGIEQAERRPLMVSVTMETGTMLVGSDIAAVVAILEPFPIDVLG
LNCATGPEQMKEHMRYLTENAPFVVSCIPNAGLPEN-VGGVAHYRLTPLELKMQLMHFVDLGVQVIGGCCGTTPAHIAALSEISSELSAAPRKVRLSYEA
AASSIYGATPYLQDNSFLIIGERLNASGSKKVRELLNKEDWDGLVAVARGQVKENAHILDVNVDYVGRDGERDMQELVNRVVTNVNLPLMLDSTEWQKME
AGLKVAGGKCILNSTNYEDERFFKVLEISKRYGAGVVIGTIDEDGMARTADQKVAIAKRAYRDAVEFGIPAREIFYDALALPISTGIEEGAETIEAIRRI
REDLQVHIVLGVSNVSFGLSARITLNSVFLHDCCEAGMDAAIISPAKILPLIKISCRDLINDRRDPLTELTTLFEGVSA-------KAAREGSDLPVEER
LKQHIIDGERIGLEDALKEGLSS-YPPLEIVNTFLLDGMKVVGELFGSGQMQLPFVLQSAETMKSAVAFLEPFMEKEEGRSAKAKFLIATVKGDVHDIGK
NLVDIILTNNGYEVINLGIKQDVNAIIAAQEEHQADCIAMSGLLVKSTAFMKDNLKAFNEAGINVPVVLGGAALTPRFVNKDGKVIYGRDAFTDLRFMDA
LV-
>tr|K9XGR8|K9XGR8_9CHRO Methionine synthase (B12-dependent) OX=1173026 OS=Gloeocapsa sp. PCC 7428. GN=Glo7428_2798 PE=4 SV=1
---RLHSPER-PVIVFDGAMGTNLQTQNLTAGGCNEYLVHTKPEAVTKVHRDFLAAGADVIETDTFGAASIVLAEDLQAYYLNKKAAELAKQVAAEPRFV
AGSMGPTTKLPT-LGHIDFDTLQAAFAEQAEGLYDGGVDLFIIETCQDVLQIKAALNAVESVERRPLMVSVTMETGTMLVGSDISAALTILEPYPIDILG
LNCATGPDRMAEHVKYLSQHSPFVVSCIPNAGLPEN-VGGQAHYRLTPMELRMALMHFVDLGVQVIGGCCGTRPDHIQQLAEIAATLKPKERYP--RYEP
AAASIYSAQPYDQDNSFLIVGERLNASGSKKCRELLNAEDWDGLVSMAKAQVREGAHVLDVNVDYVGRDGVRDMHELVSRLVTNVTIPLMLDSTEWEKME
AGLKVAGGKCLLNSTNYEEPRFFKVLELAKQYGAGVVVGTIDEDGMARTADKKFEIAQRAYNQAVEYGIPPEEIFFDTLALPISTGIEEGKATIESIRRI
REELGCHVILGVSNVSFGLNARVVLNSMFLHEAMTAGMDAAIVSASKILPLAKIACRKLIYDERDPLAELTTVFEGATT-------KRDRTDS-IPIEER
LKRHIIDGERIGLEEQLQKALEK-YAPLDIINNFLLDGMKVVGELFGSGQMQLPFVLQSAETMKAAVAYLEPFMEKQESNNSKGTVVIATVKGDVHDIGK
NLVDIILSNNGYKVVNLGIKQPVENIIDAYEQHKADCIAMSGLLVKSTAFMKENLEVFNQRGITAPVILGGAALTPKFVYEKGQVVYGKDAFSDLHFMDK
LM-
>tr|H0R674|H0R674_9ACTO Methionine synthase OX=1077974 OS=Gordonia effusa NBRC 100432. GN= PE=3 SV=1
---LLEAMSR-RVLIGDGAMGTMLQAADLTLGGCNEILNETRPDVLADIHRAYYEAGADIVETNTFGCNLSNLGDDIRIRELARKGTAIARGVADEHRYV
LGSVGPGTKLPS-LGHTTFELIRDAYTECAAGMLEGGADGILIETCQDLLQVKAAVIGSRRARAIPIFVHVTVETGTMLLGSEIGAALTALEPLGIDVIG
LNCATGPAEMSEHLRYLSRHARIPVSVMPNAGLPVL-GANGAEYPLTAPELATALSGFVEFGLSMVGGCCGTTPEHISRVAEAVAQAQQAAREP--AHES
STSSLYTPVPFAQDASFLVIGERTNSNGSKAFRESMISGDYQSCLDIAKDQTRDGAHMLDLNVDYVGRDGALDMTALASRFATASTLPIMIDSTEPQVIQ
AGLEALGGRCAVNSVNYEDSRFARIMKLVVEHGAAVVALTIDEEGQARTADHKVSIAERLIADITNWGLLEEDIIIDALTFPISTGQEEGIETIEAIRRL
KAAHEIHFTLGISNISFGLNARQVLNSVFLHECVQAGLDTAIVHASKILPMARIPALDLIYDRRDPLSKLMELFEGVSAAS----ARESRAEAALPLFER
LERRIVDGERNGLEDDLDEAMTQV-PPLKIINETLLSGMKTVGELFGSGQMQLPFVLQSAEVMKTAVAHLEPHMESTG-EDGKGRIVLATVKGDVHDIGK
NLVDIILSNNGYEVVNIGIKQPISTILEVAEDKKVDVIGMSGLLVKSTVVMKDNLEEINHRGLNYPVLLGGAALTRSYVETGGDVHYARDAFEGLRLMDD
IM-
>tr|Q05SW6|Q05SW6_9SYNE Putative methionine synthase OX=221359 OS=Synechococcus sp. RS9916. GN=RS9916_30049 PE=3 SV=1
---RLHSPER-PVLVFDGATGTSLQQLNLTAGGCNENLVVTRPDAVQSVHRLFLDAGCDVIETDTFGAASVVLAEGLQAFELNRRAAELAREVADEPRFV
AGSMGPTTKLPT-LGHIDFDTLKQAYCEQAEGLLVGGVDLFIIETCQDVLQIKAALQGVMDAERRPLMVSVTMETGTMLVGSDIAAVVAILEPFPIDILG
LNCATGPEQMKEHIRYLSECSPFVVSCIPNAGLPEN-VGGVAHYRLQPLELKMQLMHFVDLGVQVIGGCCGTTPAHIKALAELSEELTPAVRPTRLKYEP
SASSIYGATSYHQDNSFLIIGERLNASGSKKVRELLNEEDWDGLVAVARGQVKENAHVLDVNVDYVGRDGESDMRELVSRVVTNINLPLMLDSTEWQKME
AGLKVAGGKCILNSTNFEDERFFKVLELAKRYGAGVVVGTIDEDGMARTAEKKVAIAKRAYRAAVEYGIPAREIFYDPLALPISTGIEEGLETIEAIRQI
REDLGVHVVLGVSNVSFGLSARITLNSVFLHDCCEAGMDAAIVSPAKILPLIKISCRDLINDNRDPLTELTSLFEGVSA-------KDARAGSDLPVEER
LKQHIIDGERIGLEDALALGLES-YKPLEIVNTFLLDGMKVVGELFGSGQMQLPFVLQSAETMKAAVAYLEPYMEKSDGRSAKAKFLIATVKGDVHDIGK
NLVDIILTNNGYEVINLGIKQDVGAIIEAQLKHQADCIAMSGLLVKSTAFMKDNLQAFNEAGITVPVVLGGAALTPRFVNKNGKVIYGRDAFTDLRFMDA
YV-
>tr|K9YVW0|K9YVW0_DACSA 5-methyltetrahydrofolate--homocysteine methyltransferase OX=13035 OS=Dactylococcopsis salina PCC 8305. GN=Dacsa_1534 PE=4 SV=1
---RLHSPER-PVLVFDGGMGTSLQRQELTLTGCNEYLVKSKPEAIEQVHREFLEAGADVIETDSFGSSSVVLAENIQAYELSKMASELAKRVANEPRFV
AGAMGPTTKLPT-LAHIDFDTMKESYRVQAEGLYDGGADLFIIETCQDVLQIKSALNAVEELDRIPIMVSITMEMGTMLVGTEIDAALTILEPYNIDILG
LNCATGPDKMKEHIKYLSEHSPFTISCIPNAGLPEN-VGGQAHYKLTPMELRMALMHFVDLGVQVIGGCCGTRPDHIEQLADIAKELKPAERNPKC----
AAASIYSTQNYIQDNSFLIIGERLNASGSKKTRTLLNEEDWDGLVSIAKSQVKEGAHVLDVNVDYVGRDGERDMYEVVSRLVNNVTLPLMVDSTEWTKME
VGLKTAGGKCLINSTNYEEERFFKVLELGKKYGAGVVIGTIDEDGMARTAQKKFEIAQRAYRQAVESGIPPSEIFFDSLALPISTGIEEGKETMESIRLI
RENLECHVMLGVSNLSFGLNARVALNSVFLHDAVEAGMDAAIVSASKIVPLAKIECRDLIYDNRDPLTKLTEVFAGKKA-------EVAASMN-LSIEDK
LKQHIIDGERIGLNDVLDEAMKT-YPPLDIINKYLLDGMKVVGERFGAGEMQLPFVLQSAETMKAAVAHLEPHMEKDEADNAKGTFLIATVKGDVHDIGK
NLVDIILSNNGYRVINIGIKQPVDNIIAAYEEHNADCIAMSGLLVKSTAFMKDNLETFNEKGISVPVILGGAALTPKFVYGNGKVVYGKDAFSDLNFMDK
LM-
>tr|K9TN65|K9TN65_9CYAN Methionine synthase (B12-dependent) OX=56110 OS=Oscillatoria acuminata PCC 6304. GN=Oscil6304_4483 PE=4 SV=1
---RLHSPDR-PVLVFDGAMGTSLQFQNLTAGGCNEYLVYTKPEAVKIVHRGFLEAGADVIETDTFGGTSIVLAEDLRAYELNKTAAELAKSVAAEPRFV
AGSIGPGTKLPT-LGHIEFDTLKNAFSEQAEGLIDGGVDLLIVETCQDVLQIKAALNGIEAVQRLPLMVSITMEMGTMLVGSDISAALAILEPYPIDILG
LNCATGPAQMKEHIRYLAENSPFVVSCIPNAGLPEN-IGGQAHYRLTPMELRMALMHFVDLGVQVIGGCCGTQAPHIAQLAELSQSLKPKERSV--RVTP
AAASIYSAQPYTQDNSFLIVGERLNASGSKKCREMLNAEDWDGLVALGREQVREGAHILDVNVDYVGRDGVRDMHELVSRLVTNVTLPLMLDSTEWEKME
AGLKVAGGKCLMNSTNFEEPRFYKVLDLAKQYGAGVVVGTIDEEGMARTADRKFEIAKRAYDAAIAYGVPAHELFFDTLALPISTGIEEGKATIESIRRI
REELGCHILLGVSNISFGLNARQVLNSVFLHEAMQVGLDSAIVSASKILPLAKIDCRDLIYDRRDPLAKVTEFFQGKTT-------KRDRSDS-LPIEER
LKNHIIDGERIGLTDALTLALET-YPPLTIINQYLLDGMKVVGELFGSGQMQLPFVLQSAETMKAAVAYLEPFMEKEEGDNAKGTVVIATVKGDVHDIGK
NLVDIILTNNGYRVINLGIKQPVENIIQAYQEHRADCIAMSGLLVKSTAFMKENLEVFNERGISVPVILGGAALTPKFVHEKGQVVYGKDAFSDLHFMDK
LM-
>tr|H2HE18|H2HE18_CORDJ 5-methyltetrahydrofolate-homocysteinemethyltransferase OX=698968 OS=Corynebacterium diphtheriae (strain HC02). GN= PE=3 SV=1
---FLDAMKN-RVLIGDGAMGTQLQGFDLDVGGCNEILNHTRPDVVSAIHRAYFEAGADLVETNTFGCNLPNLADDIRCKELAFKGVKIAREVADEPRFV
LGSMGPGTKLPS-LGHAPYEALKNHYTEASLGMIEGGADAILVETAQDLLQVKAAVHGCQTAIQLPIVCHVTVETGTMLLGSEIGAALTAIEPLNVDMIG
LNCATGPDEMNEHLRYLSRNAHIPVSVMPNAGLPVL-GKNGAEYPLTEQELASALRGFVEYGLSMVGGCCGTTPTHIREVRKAVLGDSQAERNP--DVGD
AVSSLYTSVNLTQDTGITMIGERTNANGSKAFREAMLVGDLEKCVDIAKQQTRDGAHMLDLCVDYVGRDGTADMAQLASLLATSSTLPIMIDSTEPDVIQ
VGLEHLGGRCAVNSVNFEDSRYQRIMRLVKRHGAAVVALTIDEEGQARTAEKKIEIAERLIADITTWGLDESDIIVDTLTFPISTGQEEGIETIEAIREL
KKRHKIHTTLGLSNISFGLNARQVLNSVFLNECIEAGLDSAIAHSSKIVPMNRIDALDLVYDRRDPLQTFMRLFEGVSAAS----ASDARAAAAMPLFER
IAQRIIDGEKAGFEDDLDAGMKEK-EPLQIINENLLEGMKTVGDLFGSGQMQLPFVLQSAETMKHAVAYLEQFMEADE-DAGNGTIVIATVKGDVHDIGK
NLVDIILSNNGFNVVNIGIKQPIANILEAAEKHKADAIGMSGLLVKSTVIMKENLQEMNQAQ-DYPVILGGAALTRAYVEDEGNVHYAKDAFESLRLMQE
FM-
>tr|L7L7T9|L7L7T9_9ACTO Methionine synthase OX=1121927 OS=Gordonia hirsuta DSM 44140 = NBRC 16056. GN= PE=4 SV=1
---FLEAMSQ-RVLIGDGAMGTMLQAADLSVGGCNEILNDTRPDVLAQIHRSYFEAGADAVETNTFGCNLSNLSDDIRIRELAFKGTSIARAVADERRYV
LGSVGPGTKLPS-LGHATFAVIRDAYIECVLGMLDGGADAILIETCQDLLQLKAAVIGARRARHLPIITHVTVETGTMLVGSEIGAALAAIEPLGVDVVG
LNCATGPEEMSEHLRYLSKHSRLPVSVMPNAGLPVL-GPNGAEYPLSPEDMAQALAGFVEFGLQFVGGCCGSTPEHVRQFAEAVAATIPAIRTP--DHES
ETSSLYTAVPFNQDASFLVIAERTNSNGSKAFRDAMIAEDYQTCLEIAKEQTRDGAHMLDLNVDYVGRDGAADMRALTGRLATASTLPIMIDSTEPDVIQ
AGLEHLGGRSAVNSVNYEDSRFTRIMEHVAEHGAAVVALTIDEEGQARTADHKVAIAERLIADLTNWNLEQEDIIIDALTFPISTGQEEGIETIEAIRRL
HEKYEVHFTLGVSNISFGLNARQVLNSVFLNECVQVGLDTAIVHASKILPMARIPALDLVYDRRDPLQRLMELFEGVSAAS----ARESRAEAAMPLFER
LAARIVDGERNGLIDDLDEARAQI-PPLEIINEHLLAGMKTVGELFGSGQMQLPFVLQSAEVMKTSVAHLEQFMEASG-EDGKGRIVLATVKGDVHDIGK
NLVDIILSNNGYDVVNIGIKQPIATILSVAEEHNADVIGMSGLLVKSTVVMKENLEEMNTRG-QIPVLLGGAALTRTYVEGQGDVRYARDAFEGLTLMDE
IM-
>tr|D0LDR3|D0LDR3_GORB4 Methionine synthase OX=526226 OS=10667) (Rhodococcus bronchialis). GN= PE=3 SV=1
---FMSAMSR-RVLIGDGAMGTMLQAADLTLGGCNEILNDARPDVLEGIHRAYFEAGADAVETNTFGCNLSNLGDDIRIRELAYKGTGIARGVADENRFV
LGSIGPGTKLPS-LGHTTFAVIRDAYFECVAGMLDGGADAILIETSQDLLQVKAAVVAARRARRIPIISHVTVETGTMLLGSEIGAALTAIEPLGVDMIG
LNCATGPAEMSEHLRYLSRHARIPVSVMPNAGLPVL-GPNGAEYPLSPEELAQALHGFVEFGLDFVGGCCGTTPEHIRQVAEAVHGATPAARTP--EHAS
ETSSLYTAVPFDQDASFLVIGERTNTNGSKAFREAMIAGDYQRCLDIAKDQTRDGAHMLDLNVDYVGRDGAVDMTALASRFATSSTLPIMLDSTEPEVIR
AGLETLGGRCAVNSVNYEDSRFTRIMQLVVEHGAAVVALTIDEEGQARTADWKVRIAERLIADITNWGLAEEDIIIDALTFPISTGQEEGIETIEAIRRI
HEAHEVHFTLGISNISFGLNARQVLNSVFLHECVQAGLDTAIVHASKILPMARIPALDLVYDRRDPLQKLMELFEGVSAAS----ARESRAEAKLPLFER
LERRIVDGERNGLEDDLDEAMTTV-PPLKIINETLLSGMKTVGELFGSGQMQLPFVLQSAEVMKTAVAHLEPHMESTG-EDGKGRIVLATVKGDVHDIGK
NLVDIILSNNGYEVVNIGIKQPITNILDVAADKKVDVIGMSGLLVKSTVVMKENLEEINARGLEYPVLLGGAALTRSYVENEGDVHYARDAFEGLRLMDE
IM-
>tr|K9S5E5|K9S5E5_9CYAN Methionine synthase (B12-dependent) OX=1173025 OS=Geitlerinema sp. PCC 7407. GN=GEI7407_0887 PE=4 SV=1
---RLYSPER-PVIVFDGAMGTNLQVQNLTAGGCNEYLVFTKPEAVKTVHRQFLEAGADVIETDTFGGSTFVLAEDLRAYELNKTAAELAKSCTAEPRFV
AGSIGPGTKLPT-LGHIDYDTLKEAFTVQAQGLYDGGVDLFIVETCQDVLQIKAALNAIEEVDRLPLMVSVTMETGTMLVGSDISAVLAILEPYPINILG
LNCATGPDRMMEHIKYLCEQSPFVVSCIPNAGLPEN-VGGHAHYKLTPTELRMALMRFVDWGVQVIGGCCGTRPDHIAQLADLAQTLTPKARLNGLHYTP
AAASIYSAQPYEQDNSFLIIGERLNASGSKKCRDLLNAEDWDGLVSLAKAQVREGAHVLDVNVDYVGRDGVKDMNALVSRLVTNVTLPLMLDSTEWEKME
AGLKVAGGKCILNSTNYEEPRFFKVLELAKRYGAGIVVGTIDEEGMARTAEKKFQIAQRAYRAAVEYGIPAYEIFFDPLALPISTGIEEGKATIESIRMI
REHLGCHILLGVSNISFGLNARITLNSVFLHEAMGVGMDAAIVSAAKILPLAKIDCRQLIYDERDPLTALTKLFEGVSS-------KDARSPD-LPIEDR
LKQHIIDGERIGLEDALKVALET-YAPLTIINTFLLDGMKVVGELFGSGQMQLPFVLQSAETMKAAVAYLEPFMEKADSDSSKGTFIIATVKGDVHDIGK
NLVDIILSNNGYRVINLGIKQPVENIIEAYEQHRADCIAMSGLLVKSTAFMKENLAVFNERGITVPVILGGAALTPKFVYEKGQVIYGKDAFSDLHFMDQ
LM-
>tr|I7HBP0|I7HBP0_CORUL 5-methyltetrahydrofolate--homocysteinemethyltransferase OX=996634 OS=Corynebacterium ulcerans 0102. GN= PE=3 SV=1
---FLDAMKD-RVLIGDGAMGTQLQAFDLDVGGCNEILNVTRPDVVARIHRSYFEAGADLVETNTFGCNLPNLADGIRCRELAYEGVRIARAVADERRFV
LGSMGPGTKLPS-LGHAPFGELREYYTEAATGMIEGGADAILVETAQDLLQVKAAIHGCQQAIQIPIVCHVTVETGTMLLGSEIGAALTALEPLGIDMIG
LNCATGPDEMSEHLRFLSRNASIPISVMPNAGLPVL-GKNGAEYPLSARELAAALKGFADYGLSMVGGCCGTTPSHISAVRDAIVGTAQAQRNP--VVGD
AVSSLYTSVNLTQDTGITMIGERTNANGSKAFREAMLAADWETCVDIAKQQTRDGAHMLDLCVDYVGRDGRQDMAQLASLLSTSSTLPIMIDSTEPGVIQ
VGLEHLGGRCAVNSVNFEDSRYQRIMRLVKQHGAAVVALTIDEEGQARTAAQKVAIAERLITDITTWGLKEDDIIVDCLTFPISTGQEEGIETIEAIREL
KKRYRIHTTLGLSNISFGLNARQVLNSVFLNECIGVGLDSAIAHSSKILPMNKIDALDMVYDRRDPLQTFMQLFEGVSASS----AKDARAAAAMPLFER
IAQRVIDGEKTGIEADLDQAMAEK-EPLRIINEDLLEGMKTVGELFGSGQMQLPFVLQSAETMKHAVAYLEQFMEAED-DTGNGTIVIATVKGDVHDIGK
NLVDIILSNNGFNVINIGIKQPISNILDAAKEHNADAIGMSGLLVKSTVIMKENLQEMNAAE-HFPVILGGAALTRAYVEDNGNVYYAKDAFESLRLMQE
FM-
>tr|Q5YUV1|Q5YUV1_NOCFA Putative 5-methyltetrahydrofolate:homocysteine S-methyltransferase OX=247156 OS=Nocardia farcinica (strain IFM 10152). GN= PE=3 SV=1
---LLDTLRR-RVVIGDGAMGTMLQAVDLTLGGCNEILNETRPDVLRAIHRAYFEAGADAVETNTFGCNLSNLGDDIRIRDLSERGTRLAREVADEPRYV
LGSMGPGTKLPT-LGHAPYTALRDAYVESALGMLDGGADAILIETCQDLLQVKAAVTGSRRARRIPIITHVTVETGTMLVGSEIGAALTALEPLGIDVIG
LNCATGPDEMSEHLRHLSKHATVPVSVMPNAGLPVL-GPNGAEYPLTPEELAVALRGFVEFGLALVGGCCGTTPEHIRQVAEAVREVEEQRRSP--EPEP
AVSSMYTSVPFAQDASVLMIGERTNANGSKAFREAMLAEDWQKCLDIAKDQTRDGAHMLDLCVDYVGRDGTRDMTELASRLATSSTLPIMLDSTEPAVLQ
AGLEHLGGRCAVNSVNYEASRFQQIMRLVAEHGAAVVALTIDEEGQARTAEKKVEIAERLIADITNWGLDESDIIIDTLTFTLGTGQEEGLETIEAIREL
KRRHRVQTTLGLSNISFGLNARQVLNSVFMHECVQAGLDSAIVHASKILPMSRIPALDLIYDRRDPLQQLMAMFEGVSSSS----SKASRAEAALPLFER
LERRIVDGEKAGMEADLDEAMREV-PPLRIINETLLSGMKTVGELFGSGQMQLPFVLQSAEVMKAAVAYLEPHMEST--DDGKGRIVLATVKGDVHDIGK
NLVDIILSNNGYEVVNLGIKQPITSILDAAVDKKADVIGMSGLLVKSTVVMKENLEELNSRGVQFPVLLGGAALTRAYVENEGDVHYARDAFEGLRLMDE
IM-
>tr|B0C433|B0C433_ACAM1 Methionine synthase OX=329726 OS=Acaryochloris marina (strain MBIC 11017). GN= PE=3 SV=1
---RLHSPER-PVIVFDGAMGTSLQMQNLTAGGCNEYLIQTKPGAVATVHRNFLKAGADVIETDTFGATSIVLAEDLQAYELNKAAAELAKQVTAEPRFV
AGSMGPGTKLPT-LGHIDFDTLKAAYVEQAQGLYDGGADLLLVETCQDVLQIKAALNAIEVVARLPLMVSVTVEFGTMLVGSEIGAALTVLEPYPIDILG
LNCATGPDLMKEHIKYLSEQSPFIVSCIPNAGLPEN-VGGQAHYLLTPMELRMALMHFIDLGVQVIGGCCGTRPDHIQQLAEMSQDLKPKARLP--PYVP
AAASIMTTQSYDQDNSFLIVGERLNASGSKKCRETLNAEDWDGLVSLARSQVKEGAHVLDVNVDYVGRDGERDMRELASRLVNTVSLPLMLDSTEWTKME
AGLKVAGGKCILNSTNYEEERFYKVLELAKTYGAGVVVGTIDEDGMARTAEKKFEIAKRAYDDAINYGIPAYEIFFDPLALPASTGIEEANATISAIWQI
RDELGCHIILGVSNVSFGLNARVTLNSVFLHEAMAVGMDAAIVSASKILPLAKIECLDLIYDRRDPLTKLTTLFEGKTT-------KRDRSDS-LPVEER
LKNHIIDGERIGLEEQLDIALKD-HAPLAIINTFLLDGMKVVGELFGSGQMQLPFVLQSAQTMKAAVAYLEPMMDKEEADSGKGTVVIATVKGDVHDIGK
NLVDIILSNNGYQVINLGIKQPVDTIIAAYREHNADCIAMSGLLVKSTAFMKDNLETFNQEGITVPVILGGAALTPKFVNQNGQVIYGKDAFADLHFMDK
LM-
>tr|Q116Y2|Q116Y2_TRIEI Methionine synthase (B12-dependent) OX=203124 OS=Trichodesmium erythraeum (strain IMS101). GN= PE=3 SV=1
---RLHSPER-PVIVFDGAMGTSLQVQNLTAGGCNEYLVHTKPDAVAKVHRDFLAAGADVIETDTFGGTKIVLAEDLQAYYLNKTAAELAKSAAAEPRFV
AGSIGPGTKLPT-LGHIDFATLKDSFTEQAEGLFDGGVDLFLVETCQDVLQIKAALNGIEEIDRRPIMVSVTMEFGTMLVGSEINAALTILEPYSIDILG
LNCATGPDLMKEHIRYLSENSPFIVSCIPNAGLPEN-IGGQAHYKLTPVELKMALMHFVDLGVQVIGGCCGTRPDHIKALAEITETLKPKERKP--NYIP
AAASIYSSETYEQDNSFLIVGERLNASGSKKCRTLLNDEDWDGLVALAKSQVKEGAQILDVNVDYVGRDGVRDMHELASRLVTNVNLPLMLDSTEWEKME
AGLKVAGGKCLLNSTNYEEPRFYQVLELAKKYGAGVVVGTIDEDGMARTADKKFEIAKRAYDAAIEYGIPARELFFDTLALPISTGIEEGKATIEAIKRI
REELGCHIMLGVSNVSFGLNARQVLNSVFLHESMAVGLDGAIVSANKILPLAKIECRKLIYDQRDPLTELTKMFEGKTT-------KKDRSTN-LPIEER
LKQHIIDGERIGLEDALRKALET-YPPLDIINVFLLNGMKVVGELFGSGQMQLPFVLQSAQTMKAAVAYLQPYMEKEESDNSKGTFLIATVKGDVHDIGK
NLVDIILSNNGYRVINLGIKQPVDNIITAYREHNVDCIAMSGLLVKSTAFMKDNLETFNQEGITVPVILGGAALTPKFVHEKGKVVYGKDAFSDLNFMDK
LM-
>tr|B9LHB2|B9LHB2_CHLSY Methionine synthase OX=480224 OS=Chloroflexus aurantiacus (strain ATCC 29364 / DSM 637 / Y-400-fl). GN= PE=3 SV=1
---YLQALAE-RVLIFDGAMGTSIDTFDLTAGGCRDYLVITRPDVIEAIHTSFLEAGCDVLETCTFQSTRPRLAEGLRTVEINRAAAALARRVADRPRYV
AGSMGPTGKLPSSLSDITFAELSDIYYEQAIGLIEGGVDLLLVETSVDILEVKAALDGIRRARDIAVQAQVFLDSGRMLLGTDVPAMIATLEAMPVDVIG
LNCSTGPEHMRAAIQYLTTHSRKPISCIPNAGLPLE-VDGRTVYPMEPEPFAAILGEFVEYGVAVVGGCCGTRPAHIARLRQIL-GDAPKQRQV--EY-P
SVSSGIRAAALRQDATLTMIGERLNTLGSRKVKRLLLRDDYDGALEVAREQVESGAHMLDVCVAMTERDEKEQMTRLIKKLTLNIELPLVIDTTEADVLE
AALSIYPGRALINSVSLERAKIDKVLPLAARYGAAVIAMTIDEEGMAHTAERKVAIAERIARIAQEYGIPAEALVFDVLTFPITTGQEEAIETLEGIRLV
KQRIGCFTTLGVSNLSFGVAARAALNSVFLYHAVAAGLDTAIINPAHVTPYAEIDCEDLIFARRDALARFIAYFEAASQDN----EREDPTAA-MTVDQR
LHWKILHRKKEGIEDDIDQAVQGQ-AAVDVLNTVLLPAMKEVGDLFGAGQLILPFVLQSAEAMKKAVARLERYLDRIE---GKGKVVLATVYGDVHDIGK
NLVYTILSNNGYTVYDLGKQVPINTIIEKALEVQADAIGLSALLVSTSKQMPLCVQELYRRGIHIPVLVGGAAINRQYVDDPAGVFYCKDAFEGLETMDR
LS-
>tr|Q7NND4|Q7NND4_GLOVI 5-methyltetrahydrofolate--homocysteine S-methyltransferase OX=251221 OS=Gloeobacter violaceus (strain PCC 7421). GN= PE=3 SV=1
---LL---RH-KIVVFDGAMGTSIQKMGLGPGGCNEYLVFSKPEAIEQVHASFLEAGADVIETDTFGCSTIVLAEGIMAYELSKVAAALARQVAARPRFV
AGSIGPGTKIAT-LGQTDYDALKEAYLDNVRGLIDGGADVLMIETCQDLLQIKAVLAAAEIAVRLPVITSVTLEADKMLVGSDIATVVSALQPYTIDVLG
LNCATGPDLMSENIRYLSHNSPFYISVIPNAGLPEN-IGGHAHYHLTPGELVRYVRHYVELGINIVGGCCGTTPDHIRALATAVSGVKPRNR----SVEP
QVSSLYSAVPMHMDPAPLLVGERLNSNGSKKFRELLLAEDWDGIAGMAREQEREGAHVLDVCVDYVGRDGVRDMGEVVSRLKTRSTLPLMIDSTEVPVIH
TALKQLGGRAIVNSINLEEVRLQKLLPLCREFGSAVVALTIDEEGMARTAERKLEVARRIHDLTVKYGMKSEDLIFDPLTFTLGSGDADGIETLEGIRLI
KENLGVRTILGLSNISFGLNARQALNSVYLYYAVQNGLDMAIVHASKILPLNRIDHRKLIFDEHDPLQNLLAFYAGGKA-------RKTAVDS-APIEER
LRRRIIDGNRVGLDKDLTEALRI-YAPLDIINQHLLDGMRVVGELFGSGQMQLPFVLQSAETMKAAVGYLEPFMEKSD-HSAKGTVVIATVKGDVHDIGK
NLVDIILSNNGYRVVNLGIRQPVENIIAAFGEHQADCIAMSGLLVKSTAFMKENLEIFNERGITAPVILGGAALTRRFVESRGKVIYGKDAFADLHFLDA
LV-
>tr|A5GTA3|A5GTA3_SYNR3 Methionine synthase (5-methyltetrahydrofolate--homocysteine methyltransferase) OX=316278 OS=Synechococcus sp. (strain RCC307). GN= PE=3 SV=1
---RLHAPER-PVLVFDGATGTSLQQMDLGPGGCNENLVVTRPDAVQEVHRQFLEAGCDVIETDTFGATSLVLAEDLQTYELNVKAAQLAREMADRPRFV
AGSMGPTTKLPT-LGHVGFDAMRDSFAEQARGLLAGNVDLFIIETCQDPLQIKAALAGLEQAERRPVMVSVTMETGTMLVGSDIAAVVAILEPFPIDVLG
LNCATGPEQMKEHVRYLSAHAPFVVSCIPNAGLPEN-VGGVAHYRLTPVEMKMAMHHFIDLGVQVIGGCCGTTPAHIAALAELAQEMTPAERPVRLGAEA
SAASIYGTTPYHQDNSFLIIGERLNASGSKKVRELLNSEDWDGLVAVARGQVKENAHVLDVNVDYVGRDGEKDMHDLVSRLVTNVNLPLMLDSTEWQKME
AGLKVAGGKCLLNSTNYEDERFFKVLELARTYGAGVVVGTIDEEGMARTADRKFAIAQRAYRDAVEFGIPAHEIFYDPLALPISTGIEEGCETIEAIRRI
ITDLGVHVVLGVSNISFGLSARITLNSVFLHDCCEAGMDAAIVSPAKILPLMKISCRDLINDNRDPLTELTTMFEGVST-------KEARAGADLPVEER
LKQHIIDGERIGLEPALDEGLQN-YKPLQIVNTFLLDGMKVVGELFGSGQMQLPFVLQSAETMKSAVAYLEPHMEKTEGSSGKAKFLIATVKGDVHDIGK
NLVDIILTNNGYEVVNLGIKQSVDAIIEAQQTHQADCIAMSGLLVKSTAFMKDNLQAFNDAGISVPVILGGAALTPRFVQKNGQVIYGRDAFADLRFMDA
LV-
>tr|F4XRI5|F4XRI5_9CYAN Methionine synthase, B12-dependent OX=489825 OS=Moorea producens 3L. GN=LYNGBM3L_75820 PE=3 SV=1
---HLHSPKR-PVIVFDGATGTSLQTQNLTAGGCNEYLVHTKPEAVEKVHRGFLEVGADVIETDTFGGTSIVLAEDLQAYYLNKAAAELAKRMAAEPRFV
AGSMGPGTKLPT-LGHIDFDTLKNAYVEQALGLYDGGSDLLIVETCQDVLQIKAALNAIEEVARLPLMVSITMEMGTMLVGSEINAALTILEPYPIDILG
LNCATGPEQMKEHIKYLSECSPFVVSCIPNAGLPEN-VGGHAHYRLTPMELRMALMHFVDLGVQVIGGCCGTRPAHIEQLAEFAQTLTPKER-P--KH-P
SAASIYSSQPYEQDNSFLIVGERLNASGSKKCRTMLNAEDWDGLVSLAKSQIREGANVLDVNVDYVGRDGVRDMNELASRLVTNSTLPLMLDSTEWEKME
AGLKVVGGKCILNSTNYEEPRFYKVLELAKIYGAGVVIGTIDEDGMARTADKKFEIAKRAYNDAIAYGIPAHELFFDTLALPISTGIEEGKATIESIRRI
REELGCHVMLGVSNISFGLNARIVLNSMFLHEAMQVGMDAAIVSASKILPLAKIECRKLIYDQRDPLTKLTTLFEGKTT-------KRDRSDN-LSVEER
LKRHIIDGERIGLEEQLEKAREK-YPPLEIINTFLLDGMKVVGELFGSGQMQLPFVLQSAQTMKAAVAYLEPYMEKSEAKNAKGTFVIATVKGDVHDIGK
NLVDIILSNNGYEVINLGIKQPVDNIIDAYEKHNADCIAMSGLLVKSTAFMKDNLETFNERGITVPVILGGAALTPKFVHKNGQVVYGKDAFSDLHFMDK
LM-
>tr|C8X8S7|C8X8S7_NAKMY Methionine synthase OX=479431 OS=Y-104) (Microsphaera multipartita). GN= PE=3 SV=1
---LLTALSE-RVLVADGAMGTMLQAQDPSLGGCNEILNVTRPDIVRAVHRAYLEVGVDAIETNTFGANLANLAEDIRIYELSRAGAALARAEADEPRFV
LGSVGPGTKLPT-LGHAGYVTLRDAYQQEVAGLLDGGSDAIIVETCQDLLQAKSAILAAKRAIVVPIIVHVTVETGTMLLGSEIGAALTALEPLGVDYIG
LNCATGPAEMSEHLRYLSRHATVGVSVMPNAGLPQL-GPNGAVYPLSPAELAQALSGFVEFGLGLVGGCCGTTPEHLRQVVEAVRDLRAAGRRP--RREP
GLSSLYQAVPFQQDASVLMVGERTNANGSKAFREAMLAQDWQACIEIARAQTRDGAHVLDLNVDYVGRDGAADMASLASRLATASTLPIMIDSTEPEVIG
AGLEHLGGRSIVNSVNFEDSRYTRIMNLVAEHGAAVVALTIDEQGQARTREHKVAIAERLIADLTTWGMAESDIVVDCLTFPIATGQEEGIETIEAIREL
KRRHDLHFTLGISNVSFGLNARQVLNSVFLAECTAAGLDSAIVHPSKILPMARIPALDLVWDRRDPLQRVLEMFEGATTAA----GRATRAEAALPLDER
LQRRIIDGERNGLEADLDEALTMR-SALEIINDTLLEGMKTVGELFGSGAMQLPFVLTSAEVMKTAVAYLEPHMEKAD-SGGKGTIVLATVKGDVHDIGK
NLVDIILSNNGYSVVNLGIKQPIATILSAAQDSGADAIGMSGLLVKSTVIMKENLEEMNARGIKYPVLLGGAALTRSYVENKGDVRYARDAFEGLRLMDG
VM-
>tr|H5UTH1|H5UTH1_9MICO Methionine synthase OX=1089455 OS=Mobilicoccus pelagius NBRC 104925. GN= PE=3 SV=1
---FRTLLSE-RVIVADGAMGTMLQAADPSMNGCNEILNVTRPDIVRSVHEEYLTVGVDAVETNTFGANWANLAEDIRIEELAEAGARIAREACDAPRFV
LGSMGPGTKLPS-LLHAPYAQLRDAYQECARGLVRGGADALLVETCQDLLQAKAAIVGSRRAEDVPIICSVTVETGTMLMGTEIGAALVALEPLGIDMIS
LNCATGPAEMSEHLRHLSQNARIAVGCMPNAGLPEL-GKDGAVYPLGPDDLAKAHRRFVDYGLSLVGGCCGTTPAHLAAVVEAVGGMPVTPRDP--RPEP
AVSSLYTAVPFRQDASFLSIGERTNANGSKAFREAMLAADWEQCVEIAKNQTREGAHLLDVCADYVGRDGAEDMSEIVSRFATSSTLPLVLDSTEPGVVE
AGLERMGGRAVINSVNYEDSRFTRMMRLAKEHGAAVVALTIDENGQARTADGKVEIATRLVEAITDWGMRVEDIVVDALTFPIATGQEEGLETLEAIRRI
TEAYDIQTTLGVSNVSFGLKARVVLNSVFLDECVKAGLSSAIVNAAKILPIARIDALDLVYDRRDPLQVMLEMFEGVDSAS----LKESRLENSLPVGER
LAQRIIDGERQGLDADLDEAVAGT-PALQIINDHLLEGMKVVGERFGAGTMQLPFVLQSAETMKAAVAHLEPVIEEQV-AAGKAKVLLATVKGDVHDIGK
NLVDIILSNNGYDVVNIGIKKTVNEIIEAAEENDVDVVGMSGLLVKSTVVMKDNLEEFNKRGLKWPVMLGGAALTRVYVEDEGHVRYARDAFEGLRLMDA
IA-
>tr|H0NZA6|H0NZA6_9SYNC 5-methyltetrahydrofolate--homocysteine methyltransferase OX=1080228 OS=Synechocystis sp. PCC 6803 substr. GT-I. GN= PE=3 SV=1
---RIHSPDR-PVLVFDGAMGTNLQVQNLTAGGCNEYLVHTKPEAVATVHRAFYEAGADVVETDTFGGTPLVLAEDLQSYYLNKAAAELAKAVAAEPRFV
AGSMGPGTKLPT-LGHVDYDSLKDAYVVQVRGLYDGGVDLLLVETCQDVLQIKAALNAIEQVDRLPLMVSVTMEMGTMLVGTEMAAALAILEPYPIDILG
LNCATGPDLMKEHVKYLSEHSPFVVSCIPNAGLPEN-VGGQAFYRLTPMELQMSLMHFIDLGVQVIGGCCGTRPDHIKALADIAKDLQPKQRQP--HYEP
SAASIYSTQTYAQENSFLIIGERLNASGSKKCRDLLNAEDWDSLVSLAKSQVKEGAQILDVNVDYVGRDGVRDMKELASRLVNNVTLPLMLDSTEWQKME
AGLKVAGGKCILNSTNYEEERFYKVLEIAKEYGAGIVIGTIDEDGMGRTADKKFEIAKRAYEAAIAFGIPATEIFFDPLALPISTGIEEGKATVDAIRRI
RQELDCHILLGVSNVSFGLNARQVLNSIFLHECMQVGMDAAIVSANKILPLAKIDCLDLIYDRRDPLTKLTTLFEGKTT-------KRDKSDN-LPVEER
LKRHIIDGERLGLEEALNEALKL-YAPLDIINIYLLDGMKVVGELFGSGQMQLPFVLQSAQTMKAAVAFLEPHMDKDDSDNAKGTFLIATVKGDVHDIGK
NLVDIILSNNGYRVVNLGIKQPVENIIEAYKKHRPDCIAMSGLLVKSTAFMKENLEVFNQEGITVPVILGGAALTPKFVHQKGQVIYGKDAFADLHFMDK
LM-
>tr|B4WML6|B4WML6_9SYNE Methionine synthase OX=91464 OS=Synechococcus sp. PCC 7335. GN=S7335_4629 PE=3 SV=1
---RLKSPER-PVLVFDGAMGTSLQMQGLTAGGCNEYLVETKPEAVDKVHRGFLAVGADVIETDTFGGTALVLAEDLKAYELNKKAAEIARKAADEPRFV
AGSIGPGTKLPT-LGHVDFDTLKDAYLEQVEGLYDGGVDLMLVETCQDVLQVKAALIAIEEIDRLPLMVSVTVEQGTMLVGSEIGAALTILEPFGIDILG
LNCATGPAEMKEHIKYLSENSPFIISCVPNAGLPEN-VGGQAHYRLTPMELRMALMHFVDLGVQIIGGCCGTRPDHIEQLADLSKDLTPKPRERGPPYEP
AAASIYSPQPYEQDNSFLIVGERLNASGSKKCREMLNAEDWDGLVALAKSQIKEGAHVLDVNVDYVGRDGERDMRELVSRLVTNATLPLMLDSTEWEKME
AGLKVAGGKCILNSTNYENERFFKVLELAKRYGAGVVIGCIDEDGMARTAQKKFAIAQRAYRDAVEYGFPPYELFFDTLVLPISTGIEEAKETIAAIEMI
RDNLGCHIMLGVSNASFGLNARVVLNSMFLSEAMKVGMDGAIVSASKILPLSKIECLDLIYDRRDPLGELTTAFTGKSS-------KQLRTLEDLPLEEK
LKRHIIDGERIGLEDQLAKALEQ-YPPLEIVNTFLLDGMKVVGELFGSGQMQLPFVLQSAQTMKAAVAYLEPFMDKEDSTSGKGTVVIATVKGDVHDIGK
NLVDIILSNNGYRVVNIGIKQPVDNIISAYKEHQADCIAMSGLLVKSTAFMKENLKTFNEHGIEVPVILGGAALTPKFVNENGQVIYGKDAFADLHFMDA
LM-
>tr|K9T0S3|K9T0S3_9CYAN Methionine synthase (B12-dependent) OX=118163 OS=Pleurocapsa sp. PCC 7327. GN=Ple7327_0279 PE=4 SV=1
---RLRSPER-PVLIFDGAMGTNLQMQNLTAGGCNEYLVHTKPEAVEAVHRGFLEAGADVIETDTFGGTSIVLAEDLKAYYLNKTAAQLAKRVAAEPRFV
AGSMGPGTKLPT-LGHIDFDTLKNAYVEQAEGLYDGGVDLFVVETCQDVLQIKAALNAIEEVDRIPLMVSVTMEQGTMLIGTEIGAALAILERYPIDILG
LNCATGPDLMKPHIRYLSENSPFIISCIPNAGLPEN-LGGKAHYRLTPMELRMALMHFVDLGVQIIGGCCGTRFDHIRHLAEMAKDLKPKERHP--HYEP
SAASIYTTQPYIQDNSFLIIGERLNASGSKKCRDLLNAEDWDGLVSLAKSQVKEGAHVLDVNVDYVGRDGVRDMRQLVSRLVNNITLPLMLDSTEWQKME
AGLKVAGGKCILNSTNYEEERFLKVLELAKKYGAGVVIGTIDEEGMGRTADKKFEIAKRAYHAAVEYGIPPREIFFDTLVLPVSTGIEEGKATIEAVRRI
RQEFECHIVLGVSNVSFGLNARQVLNSVFLHEAMQAGLDSAIVSASKILPLSKIECRDLIYDRRDPLTKLTELFAGKTT-------KRDKSEN-LPVEER
LTRHIIDGERIGLEEALEEALKQ-YSPLEIINTFLLDGMKVVGELFGSGQMQLPFVLQSAQTMKAAVAYLEPFMEKSDTGGTKGTFVIATVKGDVHDIGK
NLVDIILSNNGYKVINLGIKQPVENIIQAYREHNADCIAMSGLLVKSTAFMKENLEVFNEQGITVPVILGGAALTPKFVYEKGRVVYGKDAFADLHFMDK
LM-
>tr|D6TJM7|D6TJM7_9CHLR Methionine synthase OX=485913 OS=Ktedonobacter racemifer DSM 44963. GN=Krac_11199 PE=3 SV=1
---FLSALAR-RPLIFDGAMGSNIQLYQLTAGGCNEYLVLTKPQVIEEIHTGFFEAGCDVIETDSFTASRLKLDEQILTYEVNFEAARLARRLADRPRFV
AGSVGPTGMLPSSLSNITYQQLAAIFHEQAIPLLKGGVDVLLIETSQDILEVRAAITGLRRARRVPIQAQVSLDSGRMLLGTDIAAVTTTLTALRVDIIG
LNCSTGPEYMREPVRYLSENCRLPISTIPNAGIPLN-VNGQAVYPLEPEPMAQAMREFIEFGVNIVGGCCGSSHEHLQAIRPVT-RKPQADQNI--EHQP
LVSSAIRSVEMQQDPAPLLIGERVNAQGSKKAKQALLKDDYDTLLGIGREQVEGGAHVLDVQVAVTERDEPEQMHKIVKKLSMGIEAPLVIDSTEADVIQ
AALEIYPGRVIINSINMERQRIEKVVPLALEHGSALVALTIDEEGMAKSIERKVEIARKIYDICVEYDLSPNALIFDPLTFTITTGQEEGIDTLEGIRRI
KSELGVMTVLGVSNVSFGLKARAVLNSVFLYHAIKAGLDMAIVNPTHIKPYAEIDAEDLIFNRT-ALPRFIEYFEGPQKNEG--EAKVDPTEG-MNTAER
IHWQILHRRKEGIEPLIDAIIISE-AAVEVLNTVLLPAMKDVGDRFGAGELILPFVLQSAEVMKKSVAHLENYLEKKE---GKGKVVLATVFGDVHDIGK
NLVNTILTNNGYTVYDLGKQVPLNTIIDKAIEVNADAIGLSALLVSTSKQMPLCVKELHKRGYSFPVIIGGAAINRSFVDEAPGVFYARDAFEGLDIMDR
LT-
>tr|B5IJV3|B5IJV3_9CHRO Methionine synthase OX=180281 OS=Cyanobium sp. PCC 7001. GN= PE=3 SV=1
------------MLVFDGATGTSLQQMNLTAGGCNEYLVVSRPDAVQAVHRQFLEVGADVIETDTFGATSLVLAEDIQAFALNQRAAELARQMADAPRFV
AGSMGPTTKLPT-LGHVDFDTMKASFQEQAEGLLAGDVDLFIVETCQDVLQIKAALQGIEAAQRRPLMVSVTMETGTMLVGSDIAAVVAILEPFPIDVLG
LNCATGPEQMKEHIRYLSEHSPFVVSCIPNAGLPEN-IGGVAHYRLTPLEMKMQLLHFVDLGVQVIGGCCGTTPAHIGALAELAAELTPAPRAVRLQVEP
SAASIYGTTPYHQDNSFLIIGERLNASGSKKVRELLAEEDWDGLVAVARGQVKENAHVLDVNVDYVGRDGERDMHELVSRLVTNVNLPLMLDSTEWQKME
AGLKVAGGKCILNSTNYEDERFFKVLELARAYGSGVVVGTIDEEGMARTAERKFAIAQRAYRDALEFGIPAHELFYDPLALPISTGIEEGLATVEAIRLI
RENLGVHVVLGVSNVSFGLSARIVLNSVFLHDCCEAGMDAAIVSPAKILPLIKISCRDLIYDRRDPLTALTTLFEGVSA-------KEARAGADLPVEER
LKQHIIDGERIGLETALDEALQT-YPALHIINTFLLDGMKVVGELFGSGQMQLPFVLQSAETMKAAVARLEPHMERVEGSSSKGKFLIATVKGDVHDIGK
NLVDIILTNNGYEVINLGIKQSCEAIIEAQQQHQADCIAMSGLLVKSTAFMKDNLEAFNEAGITVPVILGGAALTPRFVHGRGQVVYGRDAFADLRFMDA
LM-
>tr|B4W084|B4W084_9CYAN Methionine synthase OX=118168 OS=Coleofasciculus chthonoplastes PCC 7420. GN=MC7420_3563 PE=3 SV=1
---RLHSPQR-PVLVFDGAMGTNLQTQNLTAGGCNEYLVHTKPEAVATVHRRFLEAGADVIETDTFGGASIVLAEDLQAYSLNKAAAELAKKVAAEPRFV
AGSIGPTTKLPT-LGHIDFDTIQATFAEQAEGLYDGGVDLMIIETCQDVLQIKAALNGVEEVERRPIMVSVTVEQGTMLVGTEIGAALAILERYPIDILG
LNCATGPDRMKDHIKYLSQHSPFVVSCIPNAGLPEN-VGGQAHYKLTPMELRMALMHFIDLGVQVIGGCCGTRPEHIQQLAEIAQTLTPKERHP--EYEP
AAASIYSTQPYEQDNSFLIVGERLNASGSKKCRTLLNNEDWDGLVALARAQVREGAHVLDVNVDYVGRDGEHDMHELVSRLVTNVTLPLVLDSTEWQKME
AGLKVAGGKCILNSTNYEEERFLKVLDLAKMYGAGVIVGTIDEEGMARTADRKFAIAQRAYHQAIDYGIPAHEIFFDPLALPISTGIEEGKATIESIRRM
REELGCHIILGVSNISFGLNARVVLNSMFLHEAMAVGLDAAIVSASKILPVAKIECRKLIYDQRDPLGEITQLFEGKTT-------KRDRTDN-LPIEER
LKRHIIDGERIGLDNSLAKALET-YQPLEIINTFLLDGMKVVGELFGSGQMQLPFVLQSAETMKAAVAYLEPYMEKEDGNNAKGIMVIATVKGDVHDIGK
NLVDIILTNNGYKVINLGIKQPVDNIIEAYKEHNADCIAMSGLLVKSTAFMKDNLETFNEKGITVPVILGGAALTPKFVYQQGKVVYGKDAFSDLHFMDK
LM-
>tr|D1BTI0|D1BTI0_XYLCX Methionine synthase OX=446471 OS=/ XIL07). GN= PE=3 SV=1
---LLDAVRS-RVVVADGAMGTMIQEQDPTLGGCNEVLNVSRPDIIGAVHDAYLEAGVDAIETNTFGANWSNLGDGIRIRELARAGAAIARSRADAPRWV
LGSMGPGTKLPS-LGHTTYAHLRSTFAEQAAGLLEGGADALLIETSQDLLQAKAAVTAAHDARRVPVMVSVTVETGTMLMGSEIGAALTALQAIGVDTIG
LNCATGPDKMSEHLRYLSQHSEMPVTSMPNAGLPEL-GPHGAVYPLSATELAAAHAQFVEFGLGLVGGCCGTTPEHLAAVVDAVRGADLPPREP--QREN
AVASLYSPTDLTQELSYLAIGERTNANGSKAFREAMLEGRWDDIVDLARAQTREGAHLLDVCVDYVGRDGVADVREVVSRLASASTLPLVIDSTEPAVLQ
AGLELVGGRAVVNSVNFEESRFARIMPLVKEHGTAVVALTIDEEGQARTTDHKVAIASRLIDTLVKWGMRVDDIIVDALTFPIATGQEEAIETIEAIRQI
TAKYGVHTTLGVSNVSFGLNARTVLNSVFLHEAVAAGLDSAIVHAAKILPRTAIPALALVWDKRDPLSHLLSLFEGVDAAA----LRDAREESALPIGER
LARRIIDGNKKGLEADVDEALADR-KALDIVNDHLLSGMQVVGELFGSGQMQLPFVLQSAEVMKTAVALLEPHMEKVAGEATKGTIVLATVRGDVHDIGK
NLVDIILTNNGYKVVNIGIKQPISAMIEAAEEHDADVIGMSGLLVKSTVVMKENLQELASRGLRWPVLLGGAALTRTYVEDPGTVRYARDAFEGLRLMEP
LV-
>tr|B1WZ63|B1WZ63_CYAA5 5-methyltetrahydrofolate--homocysteine methyltransferase OX=43989 OS=Cyanothece sp. (strain ATCC 51142). GN= PE=3 SV=1
---HLNSPKR-PVLVFDGATGTSLQSQNLTAGGCNEYLVHTKPEAVEKVHRGFLEVGADVIETDTFGGTSIVLAEDLKAYYLNKKAAEIAKKMAAEPRFV
AGSMGPGTKLPT-LGHIDFDTLRDAYIEQAEGLYDGGADLLIIETCQDVLQIKAALNAVEAVNRLPIMVSITMEMGTMLVGTEISAALAILEPYKIDILG
LNCATGPEQMKEHIKYLSEHSPFIVSCIPNAGLPEN-VGGQAHYRLTPIELKMALMHFIDLGVQIIGGCCGTRPDHIKALSELSQDLTPKERHP--DYEP
SAASIYSTQPYIQDNSFLIVGERLNASGSKKCRQLLDAEDWDSLVSLAKSQVKEGAHVLDVNVDYVGRDGVRDMHELASRLVNNITLPLMLDSTEWQKME
SGLKVAGGKCILNSTNYEEERFLKVLELAKKYGAGVVVGTIDEEGMGRTADKKFEIAKRAYNAAIDYGIPAHEIFFDPLALPISTGIEEGKATVEAIKRI
REELGCHIILGISNISFGLNARQVLNSVFLYESMQVGLDGAIVSASKILPLVKIECRDLIYDRRDPLTKLTELFAGKTT-------KKDPSTS-LPIEER
LKQHIIDGERLGLEDALSEALKQ-YPPLDIINVFLLDGMKTVGELFGSGQMQLPFVLQSAQTMKAAVAYLEPFMDKEEGDSGKGKFLIATVKGDVHDIGK
NLVDIILSNNGYKVINLGIKQPVENIIQAYEEHQPDCIAMSGLLVKSTAFMKDNLEVFNERGIDVPVILGGAALTPKFVYEKGKVVYGKDAFSDLHFMDK
LM-
>tr|L7LFJ4|L7LFJ4_9ACTO Methionine synthase OX=1223544 OS=Gordonia sihwensis NBRC 108236. GN= PE=4 SV=1
---FLQAMSR-RVLIGDGAMGTMLQAADLTLQGCNEILNDTRPDVLAGIHRAYFEAGADAVETNTFGCNLSNLGDDIRIRELAYKGVSIARGVADEDRFV
LGSIGPGTKLPS-LGHTTFGAIRDAYVECVLGMLEGGADAILVETSQDLLQLKAAVVAARRARHLPIITHVTVETGTMLIGSEIGAALAAIEPLGVDVVG
LNCATGPTEMSEHLRYLSKHARIPVSVMPNAGLPVL-GKNGAEYPLTPEDMASALSGFVDYGLQFVGGCCGSTPEHIRQVAEAVKDVTPAPRHP--QHES
ETSSLYTAVPFHQDASFLVIAERTNSNGSKAFREAMISGDYEKCLEIAKDQTRDGAHMLDLNVDYVGRDGAADMTELASRFATASTLPIMIDSTEPDVIR
AGLEHLGGRCAVNSVNYEDSRFTRIMSHVVEHGAAVVALTIDEQGQARTADHKVAIAERLITDLTNWGLEEEDIIIDALTFPISTGQEEGIETIEAIRRI
KEAHQVHFTLGISNISFGLNARQVLNSVFLHECVKAGLDTAIVHASKILPMARIPALDLVYNNRDPLQKLMELFEGVSAAS----ARESRAEAALPLFER
LERRIVDGDKNGLIEDLDEARQTV-PPLSIINDTLLSGMKTVGELFGSGQMQLPFVLQSAEVMKSSVAHLEQFMEATD-EDGKGKIVLATVKGDVHDIGK
NLVDIILSNNGYDVVNIGIKQPIATILSAAEENRADVIGMSGLLVKSTVVMKENLEEMNSQG-DYPVLLGGAALTRTYVEGEGDVRYARDAFEGLSLMDE
IM-
>tr|G7H0J4|G7H0J4_9ACTO Methionine synthase OX=1073574 OS=Gordonia araii NBRC 100433. GN= PE=3 SV=1
---LLSAMSE-RVLIGDGAMGTMLQAADLTLGGCNEILNETRPDVLAHIHRAYFEAGADLVETNTFGCNQSNLGDDIRITDLAYRGTAIARGVADEYRFV
VGSIGPGTKLPS-LGHTTFGVLRDAYQQCAVGMLDGGADAILIETAQDLLQVKAAVVASRRARHIPILVHVTVETGTMLLGSEIGAALTALEPLGIDVIG
LNCATGPAEMSEHLRYLSRHARIPVSVMPNAGLPVL-GPNGAEYPLTAEELAVALRDFVDYGLSMVGGCCGTTPEHIRQVAEAVAAVERAPREQ--QHES
ATSSLYTSVPFAQDASFLVIGERTNSNGSKAFREAMIAEDYQHCLDVAKEQTRDGAHMLDLNVDYVGRDGAQDMTALATRFATSSTLPIMIDSTEPEVIR
AGLEALGGRCAVNSVNFEDSRYQRIMELVVEHGAAVVALTIDEEGQARTADDKVRIAERLIADLTTWGLTDEDIIVDALTFPISTGQEEGIETIEAIRRL
KAAHSLHFTLGISNISFGLNARQVLNSVFLHECVQVGLDTAIVHASKILPMARIPALDLVYDRRDPLQKLMELFEGVSAAS----ARESRAEAALPLFER
LERRIVDGERAGLEADLDEAMTQV-PPLQIINETLLSGMKTVGELFGSGQMQLPFVLQSAEVMKSAVAHLEPHMEATG-DSGKGRIVLATVKGDVHDIGK
NLVDIILSNNGYEVVNLGIKQPINTILEAARDKNADVIGMSGLLVKSTVVMKENLEEMNSRG-QYPVLLGGAALTRAYVENEGEVHYARDAFEGLRLMDD
IM-
>tr|L0T8Q3|L0T8Q3_MYCTU 5-methyltetrahydrofolate--homocystein methyltransferase MetH (Methionine synthase, vitamin-B12 dependent isozyme) (Ms) OX=1773 OS=Mycobacterium tuberculosis. GN= PE=4 SV=1
---LLDVLSQ-RVMVGDGAMGTQLQAADLTLGGCNEILNETRPDVLETIHRNYFEAGADAVETNTFGCNLSNLGDDIRIRDLSQKGTAIARRVADEKRYV
LGSMGPGTKLPT-LGHTEYAVIRDAYTEAALGMLDGGADAILVETCQDLLQLKAAVLGSRRARHIPVFAHVTVETGTMLLGSEIGAALTAVEPLGVDMIG
LNCATGPAEMSEHLRHLSRHARIPVSVMPNAGLPVL-GAKGAEYPLLPDELAEALAGFIEFGLSLVGGCCGTTPAHIREVAAAVANIKRPERQV--SYEP
SVSSLYTAIPFAQDASVLVIGERTNANGSKGFREAMIAEDYQKCLDIAKDQTRDGAHLLDLCVDYVGRDGVADMKALASRLATSSTLPIMLDSTETAVLQ
AGLEHLGGRCAINSVNYEDSRFAKTMALVAEHGAAVVALTIDEEGQARTAQKKVEIAERLINDITNWGVDESSILIDTLTFTIATGQEEGIETIEAIREL
KKRHDVQTTLGLSNISFGLNARQVLNSVFLHECQEAGLDSAIVHASKILPMNRIPALDLVYDRRDPLQELMRLFEGVSAAS----SKEDRLEAGLPLFER
LAQRIVDGERNGLDADLDEAMTQK-PPLQIINEHLLAGMKTVGELFGSGQMQLPFVLQSAEVMKAAVAYLEPHMERSD-DDGKGRIVLATVKGDVHDIGK
NLVDIILSNNGYEVVNIGIKQPIATILEVAEDKSADVVGMSGLLVKSTVVMKENLEEMNTRGVKFPVLLGGAALTRSYVENQGEVHYARDAFEGLKLMDT
IM-
>tr|F8AZR6|F8AZR6_FRADG Methionine synthase OX=656024 OS=Frankia symbiont subsp. Datisca glomerata. GN= PE=3 SV=1
---LLSVLAE-RVVVADGAMGTMLQAASLTLGGCNEILNVTRPDVVRAVHDAYFAVGCDAVETNTFGANLANLGEGIRIGELAEAGARIAREAADFPRFV
LGSVGPGTKLPS-LGHITYRPLRDAYQRQAAGLLAGGVDAILVETAQDLLQAKAAIIGARRARRVALIAQVTVETGTMLLGSETGAALTALEPLGIDLIG
LNCATGPAEMSEHLRYLSQQARVGLSVMPNAGLPEL-GRDGATYPLTPAELADAQDAFTDYGAALVGGCCGTTPEHLRQVVERVAGRGVRTRRP--ATWA
GAASLYQSVPFRQDTSVLMVGERTNTNGSRAFRDALIDGRWDDVVEIARAATREGAHMIDVCVDYVGRDGTVDMREVASRYATASTLPVMLDSTEPPVIE
AGLECLGGRSVVNSVNFEDSRIARVMPAVVEHGAAVVVMCIDEEGQARTVERKVQIAERTIDYLVRWGMRTADIFVDTLTFTLGTGQEEGVATIEAIREL
KRRRDVQTILGLSNISFGLKARVVLNSVFLAECVAAGLDAAIVHASRILPTARIPALDLVHDRRDPLTRFLELFSEVDGSG----AGPTRAEAALPLDER
LKRRIIDGERTGLEADLDEAMRSR-DPLAIINDTLLDGMKVVGDLFGSGQMQLPFVLQSAEVMKAAVAYLEPHMERTD-SRGKGTLVLATVKGDVHDIGK
NLVDIILSNNGYTVVNLGIKQPIGAILAAASEHDADAIGMSGLLVKSTVVMKENLAEMNTRGVTWPVLLGGAALTRAYVEGQGDVRYARDAFEGLALMDA
VM-
>tr|F6FWH1|F6FWH1_ISOV2 Methionine synthase OX=743718 OS=Isoptericola variabilis (strain 225). GN= PE=3 SV=1
---LLQAMRT-RVVVADGAMGTMIQDADPTLGGCNEVLNVSRPDIIRSVHDAYLEVGVDAIETNTFGANWSNLSDGIRIRELARAGAELARERADAPRWV
LGSMGPGTKLPS-LGHTTYAHLKATFAEQAAGLLEGGADAILVETSQDLLQAKAAVNGAREARRVPVIVSVTVETGTMLMGSEIGAALTTLQALGVDAIG
LNCATGPDQMSEHLRHLARHSEVPVACMPNAGLPEL-GPKGAVYPLTAPELATAHAQFVEFSLGLVGGCCGTTPEHLRQVVEAVRGRELTARPV--EREN
GVASLYSHTDLHQDASYLAIGERTNANGSKAFREAMLDGRWDDVVDIARAQTRDGAHLLDVCVDYVGRDGVADVREVVSRLASASTLPLVIDSTEPEVIK
AGLELVGGRAVVNSVNFEDSRFARIMPLVKEHGAAVIALTIDEEGQARTAEKKVAIASRLIDTLTDWGMRVDDIIVDALTFPIATGQEEAIETIEAIREI
TRRYGVHTTLGVSNVSFGLNARTVLNSVFLHEAVQAGLDSAIVHAAKILPRTAIPAEDLVRDRRDPLSHLLELFSGVDSAS----LRDQRAEAALPVGER
LERRIIDGARKGLEDDVEEALALG-KALDIVNTHLLGGMKVVGELFGSGQMQLPFVLQSAEVMKAAVALLEPHMERVAGDETKGTIVLATVRGDVHDIGK
NLVDIILTNNGYKVVNIGIKQPISAMIEAAEQHDADVIGMSGLLVKSTVVMKENLEELVSRGLKWPILLGGAALTRTYVEDPGTVRYARDAFEGLRLMEP
LV-
>tr|A9BAF6|A9BAF6_PROM4 Putative methionine synthase OX=93059 OS=Prochlorococcus marinus (strain MIT 9211). GN= PE=3 SV=1
---HLK-KRN-TILVFDGGMGTALQLQELSKGGCNEYLLISNPKSVEKVHRSYLEVGCDVIETNTFGATSVVLAEGLKAYQLNLAASKMAKTLAKEPRYA
AGSIGPTTKLPT-LGHIDFDDLTNSYQEQVEALITGGIDLVLVETCQDVLQIKSALLAISLAIKIPVMVSITMETGTMLIGTEISAALTILEPFNIDILG
LNCATGPEEMKSHIQYLSSHSPFITSCIPNAGLPEN-IGGKAHYRLTPIELKMQLMHFIDLGVKVIGGCCGTTPEHIKGLTQLVEEITNSNDQNLIATQP
SASSIYEKISYQQDNSFLIVGERLNASGSKKVRELLNKDDWDGLVSLAKGQLKENAHILDVNVDYVGRDGVADMSRLVSKLVTNVNIPLMLDSTDYEKME
SGLKKAGGKCILNSTNFEPDRFFQVLQLCKSHGSSVVIGTIDEEGMARTASKKLDITKRSYKEATCFGLKDSDIFFDPLVLPITTGIEDAKETILAIKNI
KSLYSVHLILGISNVSFGLNARVTLNSVFLNECINSGLDSAIISPSKILPLSKVSCLDLIYDKRDPLTQLTKAFEGVSAKS-----KSSSDLK-LPIEKR
LKSHIIEGEKEKLRENLLIALEG-YKPLHIVNTFLLDGMKVVGELFGSGQMQLPFVLQSAETMKYAVSILEPFMETDS-KSSKGKFIIATVKGDVHDIGK
NLVDIILTNNGYEVFNLGIKQDVNSIIKAQEGIQADCIAMSGLLVKSTAFMKDNLQALNEANIQVPVILGGAALTPRFVNTNGMVIYGKDAFTDLRFMDA
YM-
>tr|K9SH76|K9SH76_9CYAN Methionine synthase (B12-dependent) OX=82654 OS=Pseudanabaena sp. PCC 7367. GN=Pse7367_1002 PE=4 SV=1
---RLHSSDR-PVIVFDGAMGTNLQVQNLTAGGCNEYLLISKPEAVAKVHRDFLAAGADVIETDTFGANALVLAEDIMAYELNKKAAELAKSVAAEPRFV
AGSLGPTTKLPT-LLHIDFDAMKQSYIEQVEGLYDGGVDLLIVETCQDVLQIKVALNAIEEANRLPVIVSVTMETGTMLVGTDISAVVTILAPYKIDVLG
LNCATGPDKMVEHIRYLSENSPFVISCIPNAGLPEN-VGGQAFYKLTPPELKEHLSIFVDLGVQVIGGCCGTRPEHIAQLAAIAQELHPASRAP--QPVP
AAASIYGSQPYDQDNSFLIVGERLNASGSKKCREMLNAEEWDGLVALARSQVKEGAHILDVNVDYVGRDGDRDMHELVSRLVTNVTLPLMLDSTEASKME
AGLKVAGGKCILNSTNYEEPRFAQVIELAKAYGAGVVIGTIDEDGMARTAEKKFEIAKRAYDQCTEFGLPPYELFFDPLALPVSTGIEEGAATLEAIERI
TNELGCHIVLGVSNVSFGLNSRIVLNSVFLDLARKVGLDSAIVHASKILPLNRIKARQIIFDERDPLTTFTEMFAGATT-------KRLKSTN-LPIEEQ
LKQRVIDGDRVGFDEVLAKAMEK-YPPLDIINNFLLDGMKVVGELFGSGQMQLPFVLQSAETMKSAVAYLEPHMEKIE-GSNKGVFVIATVKGDVHDIGK
NLVDIILSNNGYKVVNLGIKQPVDNIIAAYEEHKADCIAMSGLLVKSTAFMKDNLEEFNRRGIDVPVILGGAALTKKFVEQQGRVVYGKDAFSDLNFMDA
YM-
>tr|G7CMJ8|G7CMJ8_MYCTH Putative 5-methyltetrahydrofolate--homocysteine methyltransferase MetH OX=1078020 OS=Mycobacterium thermoresistibile ATCC 19527. GN=KEK_21223 PE=3 SV=1
---LLETLSR-RVMVGDGAMGTQLQAADLTLGGCNEILNETRPDVIAEIHRNYLAAGADAVETNTFGCNLSNLGDDIKIRSLSEQGTAIARRVADERRYV
LAAMGPGTKLPT-LGHTEFGVIRDAYIEAALGMLDGGADAILIETCQDLLQLKAAVLGARRARHIPIITHVTVETGTMLLGSEIGAALTAIEPLGVDVIG
LNCATGPAEMSEHLRYLSRHSRLPVSVMPNAGLPVL-GPDGAVYPLRPDELAEALAGFVEFGLSLVGGCCGTTPEHIRQVVDAVSGVQRAGRQI--SYEP
GLSSLYTSTPFAQDASVLMIGERTNANGSKAFREAMIAEDYQRCLDIAKEQTRDGAHLLDLCVDYVGRDGVADMKALASRLATASTLPIMLDSTETDVLR
AGLEHLGGRCAVNSVNYEASRFHKTMELVAEHGAAVVALTIDEEGQARTAEHKVAIAERLIEDITNWGVEKSSILVDCLTFTICTGQEEGIETIEAIREL
KKRHDVQTTLGLSNISFGLNARQVLNSVFLHECREAGLDSAIVHASKILPMNRIDALDLIYDRRDPLQELMTMFEGVSTAD----SKESRAEAKLPVLER
LAQRIVDGERNGLEADLDEAMTIK-PPLEIINEHLLAGMKVVGELFGAGQMQLPFVLQSAEVMKAAVAHLEPHMEKSE-DDGKGRIVLATVKGDVHDIGK
NLVDIILTNNGYEVVNLGIKQPISTILEVAEDKNADVVGMSGLLVKSTVVMKENLEEMNARGVRFPVLLGGAALTRGYVEDEGEVYYARDAFEGLRLMDR
IM-
>tr|A0YZR2|A0YZR2_LYNSP 5-methyltetrahydrofolate--homocysteine methyltransferase OX=313612 OS=Lyngbya sp. (strain PCC 8106) (Lyngbya aestuarii (strain CCY9616)). GN=L8106_04161 PE=3 SV=1
---RLHSPER-PVLVFDGAMGTNLQVQNLTAGGCNEYLVHTKPEAVKTVHRGFLEAGSDVIETDTFGATSIVLAEDLIAYDLNKAAAQLAKAVTAEPRFV
AGSIGPGTKLPT-LGHIDYDTLEAAFTEQAEGLFDGDVDLFIVETCQDVLQIKAALNGIENVERRPIMVSVTVEFGTMLVGSEISAALTILEPYSIDILG
LNCATGPDLMKEHIRYLSEYSPFVVSCIPNAGLPEN-VGGQAHYKLTPTELKMALMHFIDLGVQVIGGCCGTRPDHIKALAEIAQTLKPKQRQT--QLIP
SAASIYGTQTYEQENSFLIIGERLNASGSKKCRTLLNEEDWDGLVALAKSQVKEGAQILDVNVDYVGRDGVRDMHELVSRLVTNVNLPLMLDSTEWEKME
AGLKVAGGKCLLNSTNYEEERFFKVLELAKKYGAGVVVGTIDEEGMARTAQKKFEIAKRAYHDAINYGIPAHEIFFDTLALPISTGIEEGKATVESIRMI
RAELGCHIALGVSNISFGLNARQVLNSVFLHECMAVGLDAAIVSASKILPLAKIECRRLIYDQRDPLTKLTQLFEGKTT-------KKDRATN-LPIEER
LKQHIIDGERIGLEDALVVALEK-YPPLDIINIYLLDGMKVVGELFGSGQMQLPFVLQSAQTMKAAVAYLEPYMEKDDSGSGKGTFLIATVKGDVHDIGK
NLVDIILSNNGYKVVNLGIKQPVDNIISAYREHHADCIAMSGLLVKSTAFMKDNLEAFNKEGISVPVILGGAALTPKFVYDKGKVVYGKDAFSDLNFMEQ
LM-
>tr|Q31NG7|Q31NG7_SYNE7 Methionine synthase (B12-dependent) OX=1140 OS=Synechococcus elongatus (strain PCC 7942) (Anacystis nidulans R2). GN= PE=3 SV=1
---RLHSPER-PVLVFDGGMGTTLQFQNLTAGGCNEWLIRTKPEAIATVHRQFLEAGADVIETDTFGATSIVLAEGLHAYALNVEAAKLAKAIAAEPRFV
AGSMGPTTKLPT-LGHIGYDEMKASFAEQARGLWEGGVDLFIVETCQDVLQIKAALNGIAEIDRRPLMVSVTMETGTMLVGSDVAAMLAILEPYPIDILG
LNCATGPDRMVEHIKYLSEHSPFVISCIPNAGIPEN-VGGHAHYRLTPMELRMALHRFVDLGVQVIGGCCGTKPEHIAQLAEVATQLQAKDRDHQQPFNP
SAASIYGTTPYIQDNSFLIIGERLNASGSKKVRELLNEEDWDGLVAIARSQVKEGAHVLDVNVDYVGRDGERDMGELVSRLVTNVNLPLMLDSTEWQKME
AGLKKAGGKCILNSTNYEDERFFKVLELAKQYGAGIVVGTIDEEGMARTAEKKFAIAQRAYRDALEFGIPAHEIFYDPLALPISTGIEEGRETIESIRLI
RENLGVHILLGVSNISFGLNARIVLNSVFLHDACEAGMDGAIVSAAKILPLSKIDCRDLIGDRRDPLTELTTLFEGVSA-------KEARAGSALPLEER
LKQHIIDGERIGLDQALATALEQ-YPPLEIINTFLLDGMKVVGDLFGSGQMQLPFVLQSAETMKSAVAYLEPFMDKEETDSGKGTFLIATVKGDVHDIGK
NLVDIILTNNGYKVVNIGIKQPVENIIQAYRDCNADCIAMSGLLVKSTAFMKENLATFNEEGISVPVILGGAALTPKFVYEKGQVIYGKDAFADLHFMDQ
LM-
>tr|F4CX75|F4CX75_PSEUX Methionine synthase OX=675635 OS=13855 / CB1190). GN= PE=3 SV=1
---FLDTLAR-RVVVADGAMGTMLQAADLTLGGCNEILNDTRPDVVRRIHTGYLEAGADAVETNSFGANLPNLAEDIRIRELAEKGARLAREAADEPRYV
LGSVGPGTKLPT-LGHESFARLRDAYTECGIGLLAGGADAFVIETCQDLLQVKAAVLGVRRARRIPIITQVTVETGTMLLGSEIGAALTAIEPLGVDLIG
LNCATGPAEMSEHLRTLSKHARIPLSVMPNAGLPQL-GPNGAVYPLSPDELAEALSTFVDYGLRLVGGCCGTTPDHVRAVSEAVAAVTPAVRDP--RPEP
GVSSLYASVPFRQDTSVLMVGERTNANGSKAFREAMIEERWEDCVAIAREQTRDGAHMLDLNVDYVGRDGVADMAELAGRLATASTLPIMIDSTETEVVQ
AGLEHLGGRCIVNSVNYEDSRFQRTMAVVREHGAAVVALCIDEEGQARTAEWKVRVADRLIRDLTNHGMRVEDIVVDALTFPITTGQEEALETIEAIREL
KRQYTVQTTLGISNVSFGLNARQVLNSVFLHECVTAGLDTAIVHASKILPMSKIPALDLVYDRRDPLARFMELFEGVTASS----AKAGRAEAALPLFER
LERRIVDGERVGLEADLDAALEER-PALEIINDVLLSGMKTVGELFGSGQMQLPFVLQSAEVMKTAVAHLEPHMEKTD-AAGKGTIVLATVKGDVHDIGK
NLVDIILSNNGYTVVNLGIKQPISTILSAAQEHGAHAVGMSGLLVKSTVIMKENLEEMNSRGVQLPVLLGGAALTRSYVENRGRVSYARDAFEGLRLMDA
TM-
>tr|K9WEK1|K9WEK1_9CYAN Methionine synthase (B12-dependent) OX=1173027 OS=Microcoleus sp. PCC 7113. GN=Mic7113_2842 PE=4 SV=1
---RLHSPER-PVIVFDGAMGSSLQTQNLTAGGCNEYLVVTKPEAVEKVHRGFLEAGADVIETDTFGGASIVLAEDLQAYSLNKTAAELAKRVAAEPRFV
AGSIGPTTKLPT-LGHIDFDTLQASFAEQARGLYDGGADLLIVETCQDVLQIKAALNGIEQVARLPLMVSVTMEQGTMLLGSEIGAALTILERYPIDILG
LNCATGPDRMQEHIKFLCEHSPFVVSCIPNAGLPEN-VGGHAHYKLTPMELRMALMHFVDMGVQVIGGCCGTRPDHIQQLAEIGKTLKPKERHP--EFEP
SAASIYSAQPYEQDNSFLIVGERINPSGSKKCRELLIAEDWDGLVSLAKAQVREGAHVLDVNVDYVGRDGERDMHELVSRLVTNVTLPLMLDSTEWQKME
AGLKVAGGKCLLNSTNYEEERFFQVLELAKKYGAGVVIGTIDEEGMARAADKKFAIAQRAYRQAVEYGIPPYEIFFDTLALPISTGIEEGKATIEAIRRI
REELGCHMMLGVSNISFGLNARVVLNSMFLHEAMAAGMDAAIVSPNKILPLAKIECRKLIYDERDPLAELTTLFEGKTT-------KRDRSDS-LPVEER
LKRHIIDGERIGLEEQLAKALEK-YPPLEIINTFLLDGMKVVGELFGSGQMQLPFVLQSAETMKAAVAYLEPFLDKADTNNAKGKVIIATVKGDVHDIGK
NLVDIILSNNGYQVINLGIKQPVDNIIDAYEQHKADCIAMSGLLVKSTAFMKENLEKFNERGITVPVILGGAALTPKFVHDKGKVVYGKDAFSDLHFMDK
LM-
>tr|Q0SIE4|Q0SIE4_RHOSR Methionine synthase OX=101510 OS=Rhodococcus sp. (strain RHA1). GN= PE=3 SV=1
---LLDALNQ-RVVIGDGAMGTMLQAADLTLGGCNEILNDTRPDVLKDIHRAYFEAGADAVETNTFGCNLPNLADDIRIRELAEKGTRLARDVADEDRFV
LGSMGPGTKLPT-LGHAPFAILRDAYAEAAMGMIDGGADAILVETCQDLLQVKAAILGSQRASRLPIITHVTVETGTMLLGSEIGAALTALEPLGIDMIG
LNCATGPAEMSEHLRHLSKYSSLPVSVMPNAGLPQL-GPNGAEYPLTAEELAEALSGFVEFGLGLVGGCCGTTPEHIRQVAEAVRLVEKAERNP--VHES
GTSSLYTAVPFQQDASILMIGERTNTNGSKAFREAMIAEDYQKCLDIAKDQTRDGAHMLDLNVDYVGRDGAVDMAALASRFATSSTLPIMLDSTEPAVLQ
AGLEHLGGRCAVNSVNYEDSRFQKIMRLVTEHGAAVVALTIDEEGQARTAEHKVRIAERLLDDITNWGLDESDIIIDALTFPISTGQEEGIETIEAIREL
KKRHRVHFTLGVSNISFGLNARQVLNSVFLHECTEAGLDTAIVHASKILPMARIPALDLVYDRRDPLQKLMELFEGVSAAS----ARESRAEAALPLFER
LERRIVDGERNGLDDDLTAAMEEK-PPLAIINETLLSGMKTVGELFGSGQMQLPFVLQSAEVMKAAVAYLEPHMEATD-EDGKGRIVIATVKGDVHDIGK
NLVDIILSNNGYDVVNLGIKQPIATILDAAIEQKADVIGMSGLLVKSTVVMKDNLQELNAKGVKFPVLLGGAALTRSYVENEGDVSYARDAFEGLHRMDE
IM-
>tr|D3F0W9|D3F0W9_CONWI Homocysteine S-methyltransferase OX=469383 OS=ID131577). GN= PE=3 SV=1
---YLDAIRS-RVVVFDGGMGATLEQFELTEGKCHEALILHRPDVIEGVHTTMLDAGADVVETDTFQASRLKLEEGLHTLEINRRGAEIARKAA--HRYV
AGSIGPTGFLPASLGNISFRALVEVFAEQAQGLIEGGADLLMIETAQDILEVKASVFGAREARKIPIQVSVLLPGGKMLLGTDISAVLTTLTALDVDALG
LNCSTGPEDMRDAIRFLGEFSPVPVHCIPNAGLPLQGPDGETIFPEKPEPLAASLTEFVRYGVSIVGGCCGTTAAHIRAIADSV-KGHVAPRPA--AP-P
HVSSMIAATPLAQEPRPTIVGERVNSQGSRKAKELLLADDYDGLLQIAENQVELGAHVLDLCVALTERDEDVQMRTLAKRVSLSLPAPIQVDSTEPEVME
AALEQIPGRAIVNSVNLERDKLDRVVPICLQHGAALIALTIDEESMAKTAQRKLDVAKRIHGYVCEHGMAPELLIFDALTFTLATGSDEAVETIEGIRLI
KAELGVLTSLGVSNVSFGFGAREVLNSVFLHHCVEAGLDLAMVHPKDVTPYSEIPADDLVFNRRDATQRFIEHFEGESAED----ESADPTAG-MEPEEA
LHFHILRRKKDGVEDWIDRSVEKI-GAVPTLNDVLLPAMKEVGDKFGAGELILPFVLQSAEVMKKAVARLENYLDRLE---GKGTVVLATVFGDVHDIGK
SLVNTILTNNGYTVVDLGKQVPVSTILDAAQEHRANAIGLSALLVSTSKQMPLAVQELHQRELPYPVLIGGAAINRDFPHGEPGVFYCKDAFEGLAKMDE
IV-
>tr|A8G4U9|A8G4U9_PROM2 Putative methionine synthase OX=93060 OS=Prochlorococcus marinus (strain MIT 9215). GN= PE=3 SV=1
---YLNRDEK-PLIIFDGGTGTSFQNLNLTAGGCNENLVLSSPNVVERVHTSFLEAGCHVIETNTFGASSIVLDEDIKAYEINKNAALIAKKAAAKPRFV
AGSIGPTTKLPT-LGHIDFDELKQSYKEQIYGLTDGGVDLLLIETCQDVLQIKSALLASKEVIDIPIMVSITMETGTMLVGSDIASALTILEPFNIDILG
LNCATGPEQMKEHIKYLSENSPFAISCIPNAGLPEN-IGGVAHYRLKPIELKMQLMNFIDFNVQLIGGCCGTTPEHIKYLSSIIDEIIHKERSSKNNLSP
SASSIYNSVPYKQDNSILIVGERLNASGSKKVRELLNNDDWDGLVSIAKQQQKENAHVLDVNVDYVGRDGVKDMKEITSRLVTNINLPLMIDSTDADKME
SGLKSAGGKCIINSTNYENERFDQVLNLALGYGSGLVVGTIDEDGMARDADKKYNIVKRAINRTRECGLSDYELFFDPLALPISTGIEEAKETINAISTI
RKNFDIHIILGISNISFGLSSRINLNSIFLDECIKAGLDSAIIAPNKILPLSKISCLDLIYDKRDPLVELTKAFQDLSIQD----FKKASSNN-LTLEES
LKNHIIDGEKIGLEDQLNKALKK-YKPLEIINNFLLDGMKVVGDLFGSGQMQLPFVLQSAETMKFAVSILEPYMETDE-SISNGKLLIATVKGDVHDIGK
NLVDIILTNNGYDVINLGIKQDVSAIINAQKKHNADCIAMSGLLVKSTAFMKDNLEAFNNENISVPVILGGAALTPKFVNEKGKILYGKDAFTDLKFMNE
YM-
>tr|A4FGJ4|A4FGJ4_SACEN Putative 5-methyltetrahydrofolate:homocysteine S-methyltransferase OX=405948 OS=Saccharopolyspora erythraea (strain NRRL 23338). GN= PE=3 SV=1
---FLAAIGE-RVLVADGGMGTALQAYDLSLNGCNEILNETRPDVVSSVYRGFLEAGSDAIETNTFGTNLANLGEGIRIRDLAEKGTRLAREAADEPRFV
LGSMGPGTKLPT-LGHAPYADLRDAYVENVLGMIDGGIDVVLVETSQDLLQTKAAIVAAKRARWLPIIAQVTVETGTMLVGSEIGAALTALEPLGIDMIG
MNCATGPAEMSEHLRVLSQHARVPISVMPNAGLPEL-GPNGAVYPLKADELAEALAGFVNFGARLVGGCCGTTGEHVRAVSEAVASLTPPERTP--EVIP
SVSSMYQTVPFEQDASILNVGERTNANGSKAFREAMLEERYEDCVEIAKAQTREGAHMLDLCVDYVGRDGTKDMRELASRLATASTLPIMVDSTEPDVIQ
AGLEHLGGRCAVNSVNYETGRFQRVMEMVREHGATVVVTCIDEEGQARTRDWKLRVAERMIEDLTNWGLEKSAIIIDCLVFPITTGQEEGIETIEAIREL
KKRHDVQTTLGLSNVSFGLNARQVLNSVFLNECREAGLDSAIVNSSKILPMTKIDALDLVYDRRDPLQKLMELFEGQTAKS----SSASRAEAKLPLFER
LEKRIVDGERNGLEADLEAAMQEK-PPLEIINQNLLGGMKIVGDLFGSGQMQLPFVLQSAEVMKAAVAHLEPHMEKDD-SGGKGRLLLATVKGDVHDIGK
NLVDIIVSNNGYEVVNIGIKQPINAILDAAEEHKVDAIGMSGLLVKSTVIMKENLEEMNSRGIKYPVMLGGAALTRSYVENQGDVRYAKDAFEGLHLMDR
MM-
>tr|K9Y0B1|K9Y0B1_9CYAN Methionine synthase (B12-dependent) OX=111780 OS=Stanieria cyanosphaera PCC 7437. GN=Sta7437_4357 PE=4 SV=1
---RLNSSDR-HVLVFDGAMGTNLQVQNLTAGGCNEYLVHTKPEAVEKVHRGFLEAGADVIETDTFGGTSIVLAEDLQAYYLNKTAAELAKRLTTEPRFV
AGSMGPGTKLPT-LGHIDFDTLRDAYVVQAEALYDGGVDLLLVETCQDVLQIKAALNAIEEVARIPLMVSVTMEMGTMLVGTEIDAALAILERYPINILG
LNCATGPDLMKDHIKYLSEHSPFIVSCVPNAGLPEN-VGGQAHYKLTPMELRMSLMHFVDLGVQIVGGCCGTRYEHIQALAEMTKDLKPKERRP--HYEP
SAASIYSTQPYIQDNSFLIVGEKLNASGSKKCRELLNVEDWDSLISMAKAQVKEGAHVLDVNVDYVGRDGEKDMHELASRLVNNVTLPLMLDSTEWTKME
AGLKVAGGKCILNSTNYEEERFFQVLELAKKYGAGVVIGTIDEDGMGRTADKKFAIAKRAYDAAVEYGIPPHEIFFDPLALPVSTGIEEGKATVEAIKRI
REELGCHILLGVSNVSFGLNARQVLNSVFLHECMAVGLDAAIVSANKILPLSKIDCLDLIYDRRDPLGELTTLFAGKKA-------KKSEADN-LPIDER
LKQHIIDGERIGLEDALNEALQN-HPPLEIINTFLLDGMKVVGELFGSGQMQLPFVLQSAQTMKAAVAYLEPFMDKEEADKGKGIFIIATVKGDVHDIGK
NLVDIILSNNGYKVINLGIKQPVENIIQAYEEHKADCIAMSGLLVKSTAFMKDNLETFNEKGITVPVILGGAALTPKFVHQKGKVIYGKDAFADLHFMDK
LM-
>tr|E0DEX4|E0DEX4_9CORY Methionine synthase OX=553207 OS=Corynebacterium matruchotii ATCC 14266. GN= PE=3 SV=1
---FLDALHS-RVLIGDGAMGTQLQGFDLDVGGCNEILNDTRPDVVAQIHRAYFTAGADLVETNTFGCNLPNLADNIRCQELAYKGTRIARTVADERRFV
LGSMGPGTKLPS-LGHAPYLDLKTYYREAALGMVDGGADGILIETAQDLLQVKAAIHGCQEAYRLPIVCHVTVETGTMLLGSEIGAALTALEPLGIDMIG
LNCATGPDEMSEHLRYLSRNARIPVSVMPNAGLPIL-GKNGAEYPLKPAELAASLKTFIEYGLAMVGGCCGTTPEHITAVHTMVTG--PAERTT--PDSD
AVSSLYTSVNLTQDAGVTIIGERTNANGSKAFREAMLAGDLETCVDIAKQQTRDGAHMLDLCVDYVGRDGRDDMAALASLLATSSTLPIMIDSTEPNVIQ
TGLEHLGGRCAVNSVNFEDSRYQRIMQLVKTHGAAVVALTIDEEGQARTAEKKLAIAERLITDITNWGLDESDIIVDTLTFPISTGQEEGIETINAIREL
KARHRVHTTLGLSNISFGLNARQVLNSVFLNECVAAGLDSAIAHSSKLVPMNRIEALDMIYDRRDPLQTFMDLFEGVSAAE----AKDARAAAALPLFER
LSQRIIDGEKTGIETDLDAAMAEK-SPINIINQDLLGGMKTVGELFGSGQMQLPFVLQSAETMKHAVAYLENYMEATD-DSGKGTMVIATVKGDVHDIGK
NLVDIILSNNGYNVINIGIKQPIATIISAAREHNADVVGMSGLLVKSTVVMKENLEEMNAQN-DIPVILGGAALTRSYVEHAGDVHYARDAFEGLSLMDE
IM-
>tr|F6ENE1|F6ENE1_AMYSD Methionine synthase OX=443218 OS=Amycolicicoccus subflavus (strain DSM 45089 / DQS3-9A1). GN= PE=3 SV=1
---LLDALTQ-RVVIGDGAMGTMLQAAHLTLEGCNEILNDTRPDVLREIHLAYLEAGADAIETNTFGCNLPNLADDIRIRELAEKGTRIAREAADEDRFI
LGSVGPGTKLPT-LGHAPFASLRDAYAECALGMIDGGADAILIETCQDLLQVKAAIIGAQHATRLPIITHVTVETGTMLLGSEIGAALTALEPLGIDLIG
LNCATGPEEMSEHLRHLSKHSRLPVSVMPNAGLPVL-GANGAEYPLTAEELGVALSGFVEFGLALVGGCCGTTPEHIRQLRAAVLETRQAERHP--RPEP
GVASLYSHVPFKQDSSILMIGERTNANGSKAFREAMLAGDFQKCLDIAKDQTRDGAHMLDLCIDYVGRNGAEDMSELASRLATSSTLPIMLDSTEPEVLR
AGLEHLGGRCAINSVNYEDSRFYRIMRLVKEHGAAVVALCIDENGQARTAEDKVRVAERLIDDITNWGLRDEDIIVDCLTFTIGTGMEEGAATIEAIRQL
KERRRVHTTLGLSNISFGLNARQVLNSVFLHECVEAGLDTAIVHASKILPMSKIGALDLVYDRRDPLQKFMDLFEGVSAAS----ARESRAQAALPLFER
LERRIIDGERNGLDTDLEEAMKEK-PPLAIINENLLAGMKVVGELFGSGQMQLPFVLTSAEVMKTAVAHLEPHMEATG-DSGKGRIVLATVKGDVHDIGK
NLVDIILSNNGYEVINLGIKQPIANILDAAVEKKADVIGMSGLLVKSTVVMKENLEELNSRGFKFPVLLGGAALTRSYVENHGDVLYARDAFEGLRLMDT
IM-
>tr|E4U971|E4U971_OCEP5 Methionine synthase (B12-dependent) OX=670487 OS=506). GN= PE=3 SV=1
---YLRALSE-RVLVFDGAMGTELQKYDLKPGGCPEILNLTRPDVIREIHERYLEAGADVIETNTFGVMPHVIGEGLRARELAEAGARLARQMADASRFV
AGSLGPGTKLIS-LGQISWDELFESYRTAARGLIAGGVDLIVIETAQDILQVRCAVQAVRQAREVPLQTQVTIETGQMLVGSDAEAALAALESLPVDVVG
MNCATGPDLMDPHIRVFAEHSSRPTVCMPNAGLPRN-EDGQVVYDLTPEELARWQTKFVEYGLNVVGGCCGTGPEHIRALSQALAGAPTRPRPA--RLPP
AVASLYQAVELRPQAGVLMIGERTNATGSKKFRELLFAGDLDGIVELAQDQVAGGAQMLDVSVAWTGRDEKADMVRVVERLAREVDAALMIDSTQPEVIE
AALEHVPGRPVINSVNFEEARFDRTAALARAHGAAVVALTIDEEGMAKTVERKLEVAQRIYRRLVKHGFLPEDILFDLLTFPITQGDEDALATLEAMRYL
KDALGVGFVLGVSNVSFGLKARKVLNAVFLHEAQQAGLTAAIVHPGKIVPVNQIPARDLIYDRRDPLFAFIDYFESHTLDE----AR--KDA-ELPVEER
LHRRIVEGRKKGLEEDLAEALEK-YRAEEIINRILLGGMQEVGDLFGSGQMQLPFVLKSAEVMKAAVAWLEPHMERQG-S-HKGTLVLATVKGDVHDIGK
NLVDIILSNNGYRVINLGIKQPIDSILEAVERYRPDAVGMSGLLVKSTAVMKENLEHMAALG-RIPVILGGAALNRSYVERPT-VHYAPDAFAGLKLMEE
IV-
>tr|B0JFV5|B0JFV5_MICAN 5-methyltetrahydrofolate--homocysteine methyltransferase OX=449447 OS=Microcystis aeruginosa (strain NIES-843). GN= PE=3 SV=1
---YLNGPKH-PVLVFDGAMGTSLQSQNLTAGGCNEYLVHTKPSAVAKVHEAFLAVGADVIETDTFGGTSIVLAEDLQAYYLNKTAAELAKACANKPRFV
AGSMGPGTKLPT-LGHIDFDTLKNAYVEQVEGLYDGGADLLLVETCQDVLQIKAALNAIEEVQRLPLMVSVTMEMGTMLVGTEINAVVSILQPYKIDILG
LNCATGPDLMKPHIKYLSENSPFIVSCIPNAGLPEN-VGGQAHYRLTPVELKMALMHFIDLGVQIIGGCCGTRPDHIQALAELCQGLTPKSRHY--HYEP
SAASIYSTQPYIQDNSFLIVGEKLNASGSKKCRELLNAEDWDSLVSMAKAQVKEGAHILDVNVDYVGRDGVRDMHQLASRLVNNVTLPLMLDSTEWEKME
AGLKVAGGKCILNSTNYEEPRFYQVLDLAKKYGAGVVIGTIDEEGMGRTAEKKFQIAKRAYYAAIEYGIPPYEIFFDPLALPISTGIEEGKATIEAMGRI
RQELECHILLGVSNISFGLNARQVLNSVFLNEAMQVGMDGAIVSANKILPLAKIECRDLIYDNRDPLTKLTELFAGKTT-------KKDPSNN-LPVEER
LKQHIIDGERLGLEDALNQALQD-YPPLDIINIFLLDGMKVVGELFGSGQMQLPFVLQSAQTMKAAVAFLEPFMEKKEGNNAKGTFIIATVKGDVHDIGK
NLVDIILTNNGYKVINLGIKQPVENIIEAYKEHKADCIAMSGLLVKSTAFMKENLEVFNEKGITVPVILGGAALTPKFVHDKGQVIYGKDAFSDLHFMDK
LM-
>tr|A2BWK5|A2BWK5_PROM5 Putative methionine synthase OX=167542 OS=Prochlorococcus marinus (strain MIT 9515). GN= PE=3 SV=1
---YLNRDDK-PIIIFDGGTGTSFQNLNLSSGGCNENLVLSSPNIVEQVHNSFLEAGCHVIETNTFGASSIVLDENIKAYDINKKAAQIAQKSVNSPRFV
AGSIGPTTKLPT-LGHIEFDKLKESYEEQIHGLIDGGIDLLLIETCQDVLQIKSALFASQEVIDLPIMISITMETGTMLVGSDIASALTILEPYKIDILG
LNCATGPVQMKDHIKYLSENSPFAISCIPNAGLPEN-VGGVAHYKLTPIELKMQLMNFIDYNVQLIGGCCGTTPEHIKYLSSIIDEIVDKKKINTTEKNP
SAASIYNSVPYKQDNSILIVGERLNASGSKKVRELLNKDDWDGLVSIAKQQQKENAHILDVNVDYVGRDGVKDMKEITSRLVTNINLPLMIDSTEADKME
SGLKTAGGKCIINSTNYEDDRFNQVLKLALDYGSGIVIGTIDEDGMARTSDKKYNIAKRALIQTRSSGLEDYEVFFDPLALPISTGIEEAKATIEAILKI
RKSFDIHIILGISNISFGLSSRINLNSIFLDECIKAGLDSAIIAPNKILPLSKISCLDLIYDRRDPLVELTKAFQDLTISD----FKKASTNK-LSLEEK
LKNHIVDGEKIGLEENLNNALKK-YNPLEIINTYLLDGMKVVGELFGSGQMQLPFVLQSAETMKFAVSVLEPHMETDE-KVSNGKLLIATVKGDVHDIGK
NLVDIILSNNGFDVINLGIKQDVSAIIEAQKIHKADCIAMSGLLVKSTAFMKDNLEAFNNAEINVPVILGGAALTPKFVNEKGKILYGKDAFTDLQFMNE
FM-
>tr|K6W5P4|K6W5P4_9MICO Methionine synthase OX=1184607 OS=Austwickia chelonae NBRC 105200. GN= PE=4 SV=1
---FRALLGR-KVIVADGGMGTMLQAQDPSLGGCNEILNVTRPDIVRSVHDAYLDVGCDAIETNTFGANLANLGEDIRIYELARAGAAIAREAADAPRFV
LGSIGPGTKLPS-LGHTTYAELRDAYQTCAAGLIDGGADALLVETCQDLLQAKAAAAGCRRATDQPIIVQVTVETGTMLMGSEIGAALAALTPLGIDAIG
LNCATGPAEMSEHLRHLSTYSPIPLSVMPNAGLPEL-TKDGACYPLTPDELAESHRRFVDYGVSIVGGCCGSTPAHMAAVVEAVSGMDVPARQI--AREP
SVASLYTAVPLHQDASFLSIGERTNANGSKAFREAMLDGRWDDCIDIAREQIRDGAHLLDVCVDYVGRDGRDDMSLLAFRLATTSTLPLVLDSTEPNVVQ
AGLERLGGRAVINSVNYEDSRFVRMMRLVAEHGAAVVALTIDESGQARTTAHKVAVADRLVTALTEWGMAVEDIIVDCLTFPIATGQEEGIETIEAIREI
NLRHGISTTLGVSNVSFGLKARVVLNSVFLAECAKAGLSSAIVNSAKILPVARIPALDLVYDRRDPLARMLELFEGVDSAS----VKESRAEAALPLGER
LARRIVDGERTGLETDLDEALAGT-GPLEIINDHLLAGMKTVGELFGSGRMQLPFVLQSAETMKTAVAHLEPAIEAAT-AAGKAKILLATVKGDVHDIGK
NLVDIILSNNGYEVVNLGIKQPINEIISAAEEHQVDAIGMSGLLVKSTVIMKENLEELNTRGLRWPVLLGGAALTRAYVETAGEVRYARDAFEGLRLMDA
IA-
>tr|E6J8H1|E6J8H1_9ACTO Putative 5-methyltetrahydrofolate:homocysteine S-methyltransferase OX=910954 OS=Dietzia cinnamea P4. GN=ES5_07599 PE=3 SV=1
---LLDAARR-RVLIGDGAMGTMLQAVDLDVGGCNEILNATRPDVVEGIHRAFFEAGADLVETNTFGCNLSNLGDDIRIGELAEKGAAIARRVADEPRMV
LGSLGPGTKLPS-LGQTTFEDIRDAYSKAAEGLARGGADAYLIETSQDLLQVKAAVLGCQDGRRLPIISHVTIETGTMLLGSDIGAALTALQPLGIDMIG
LNCATGPAEMVEHLRYLSRHAEIPVSVMPNAGLPEL-GEHGAVYPLGAEEFGPQVADFVEFGLSMVGGCCGTTPEHITRLKEQVSARTRAERTV--EPVN
AVASLYSSTPLRADAGIIMIGERTNANGSKRFREAMLASDWDTCMDIAKEQMRDGAQMVDLCVDYVGRDGSGDMAELAGRMATSSTLPIMLDSTEPEVIR
AGLEKLGGRCAVNSVNYEASRFQRIMRLVSRHGAAVVGLTIDEEGQARTADRKVEIAERLIADLTNWGMAEEDIIIDCLTFPISTGQEEGIETIEAIRRL
TEAHRIHTTLGLSNISFGLNARQVLNSVFLHECVQAGLDSAIAHSSKILPMSKIDALDLVYDRRDPLQVFMELFEGVSAAG----AKNARAEAAMPLMER
LAARIVDGERKGLEEDLDAAMVEI-PPLEIINEHLLGGMKTVGELFGSGQMQLPFVLQSAETMKAAVAHLEPHMEASD-EDGKGRIVLATVKGDVHDIGK
NLVDIILSNNGYDVVNIGIKQPISEIISAAREHKADVIGMSGLLVKSTVVMKDNLAELNSEGIEFPVLLGGAALTRSYVEVQGDVFYARDAFEGLRLMDE
VM-
>tr|Q01YW7|Q01YW7_SOLUE Methionine synthase (B12-dependent) OX=234267 OS=Solibacter usitatus (strain Ellin6076). GN= PE=3 SV=1
---LNDSLEQ-RVLVLDGAMGTMIHQAPLSEGNCPEILNVTRPDVIQDIHRQYLEAGADIIETNTFGGTRIALADKLRAYELNFAAAKLAREVADQPRFV
AGSIGPTNKDLNITGSTTFPEIKAAYYEQAKGLVEGGADYLLIETCFDTGSLKAGLVAVEQLIQIPVVASVTIETGTMLGGQQIDALYASIGNHELLGVG
MNCATGPDLMTDHIRTLNEMSAHRISCYPNAGLPNA----EGKFGETPDSLAAQLEKFAQGWLNFVGGCCGTTPAHIQAIAQMIQG--KRPRTP----AS
KHRAYYSGIDLVESNRPLLVGERTNVIGSRLFKNLIADEKWEEATDIARRQVRNGAHVIDVCLQSTDREELEDIRPFYEKLIRKIKAPIMIDTTDPKAVE
LALTYCQGKSIINSVNLEEEKFERLCPIAKLYGAALVVGSIDEDAQAFTRERKVAVAERSYRLLTKYGIPGEDIIIDPLVFPCATGDVNAVETIEGIRLV
KQALYAKTVLGISNISFGLPAREVVNSVFLYYCTKAGLDLAIVNAEKLERFASIPAEHLLFTPPESLRTAAEDWRAQSPEQ-------KAANQDMPLDQR
LANYIIEGTKDGLIADLDRKRAEGATPLEIINGPLMAGMSEVGRLFNNNELIVAEVLQSAEAMKAAVNHLEQFMEKAD-TAARGKVLLATVKGDVHDIGK
NLVEIILANNGYEVINLGIKVPPDVLIQAFREHMPDAIGLSGLLVKSTQQMVITATDLKAAGIDVPLLVGGAALSEKFTRTSEAVCYAKDAMTGLSLMNR
LM-
>tr|K9RUE4|K9RUE4_SYNP3 Methionine synthase (B12-dependent) OX=195253 OS=Synechococcus sp. (strain ATCC 27167 / PCC 6312). GN=Syn6312_2454 PE=4 SV=1
---RLHSPNR-PVIVFDGAMGTNLQVQNLTAGGCNEYLVMTKPEAVAKVHRDFLAAGADVIETDTFGGTSIVLAEDLRAYELNKTAAELAKKLTAEPRFA
AGSIGPGTKLPT-LGHIDYDTLQAAFAEQARGLWDGGVDLFLVETCQDVLQIKAALNGILQVDRRPIMVSVTMEQGTMLVGSEIGAALTILEPYPIDILG
LNCATGPDLMADHIRYLTKHSPFVVSCIPNAGLPEN-IGGHAHYKLTPMELRLTLSRFVDLGVQVIGGCCGTRPDHIQALAEIAQTLTPKERHP--EIIP
AAASIYSPQPYDQDNSFLIIGERLNASGSKKCRDLLNAEAWDGLVALGREQVREGAHILDVNVDYVGRDGVRDMHNLVSRLVTNVTLPLMLDSTEWEKME
AGLKVAGGKCLLNSTNFEEPRFYKVLELAKTYGAGIVVGTIDEEGMARTAEKKFAIAQRAYRAALEFGIPAHEIFFDPLALPVSTGIEEGLATIESICQM
RQELGCHILLGVSNISFGLNARQVLNSMFLHEAMQAGMDAAIVSAAKILPLARIECQDLIYDRRDPLGKLTDVFAGKTT-------KRDRTDA-LPVEQR
LKQHIIDGERIGLEEQLQKALET-YPPLEIINTFLLDGMKVVGELFGSGQMQLPFVLQSAETMKAAVAFLEPFMEKQDVSNGKGLFIIATVKGDVHDIGK
NLVDIILTNNGYRVINLGIKQPVENIIAAYEEHQADCIAMSGLLVKSTAFMKENLEVFNERGITVPVILGGAALTPKFVHEHGQVIYGKDAFADLHFMDQ
LM-
>tr|K9UHH6|K9UHH6_9CHRO 5-methyltetrahydrofolate--homocysteine methyltransferase OX=1173020 OS=Chamaesiphon minutus PCC 6605. GN=Cha6605_3573 PE=4 SV=1
---RLHSPER-PVIVFDGAMGTNLQVQNLTAGGCNEYLVHTNPEAVAKVHRDFLAAGADVIETDTFGGTAQTLGEGLQVYYLNKTAAELAKKCTAEPRFV
AGSIGPGTKLPS-IGHIDYDSLEQAYTEQATGLLDGGVDLFLIETCMDVLQIKAAINGLEQVVRIPIMVSATFEQATMLSGSDVATLLTALQPFPIDILG
LNCATGPDLMAPHIKHLCEQSPFVVSCVPNAGLPEN-IGGHAHYKLTPIELKLAMYKFVDWGVQVIGGCCGTRPEHIKELAEIGATLKTKVRIP--IFEP
AASSLMSVQPYHQDNSFLIIGERLNASGSKKCRDLLNEENWDGLVSLAKSQVREGAHVLDVNVDYVGRDGVKDMHEVVSRVVNNVSLPLMLDSTEWEKME
AGLKVAGGKCLLNSTNYEEERFYKVLEIAKKYGAGIVIGTIDEEGMARTAQKKFEIAKRAYDAAVAYGFPPYEIFFDPLALPISTGIEEGKATVESIEMI
RQNLECHVLLGLSNISFGLNARQVLNSMFLHECMAVGMDAAIVSPNKILPLAKITCRNLIYDRRDPLGLLTTMFEGVTT-------KRDKSDK-LPLEQK
LTRHIIDGERVGLEANLMKAIEK-YPPLDIINIYLLDGMKVVGELFGSGQMQLPFVLQSAETMKAAVAFLEPHMDKDVGSNAKGKFVIATVKGDVHDIGK
NLVDIILSNNGYEVINMGIKQPVEAIIQAYEEHKPDCIAMSGLLVKSTAFMKENLEVFNEKGITIPIILGGAALTPKFVYNKGQVIYGKDAFADLNFMDA
LM-
>tr|B7A7K0|B7A7K0_THEAQ Methionine synthase OX=498848 OS=Thermus aquaticus Y51MC23. GN=TaqDRAFT_5403 PE=3 SV=1
---YLKALLE-RPVIFDGAMGTELQKRDLTPGGCPEVLNATRPEVIREIHLAYLEAGAEVIETNTFGALRHVLAEGLRAEELAYLGARLAKEAAEP--FV
AGALGPGTKLIS-LGQITWDELFAAYKEAVRGLLRGGVDLVLLETAQDILQVRCAVLAAREAREVPLQVQVTIETGTMLVGTDEQAALAALESLPIDVVG
MNCATGPDLMDNKIRYFAQNSTRFVSCLPNAGLPRN-EGGKVVYDLTPEELARWHRKFVEYGVNAVGGCCGTGPEHIRRVAEAVRGLPAPGRPK--AFPP
QVASLYLAVPLKQEASVFLVGERLNATGSKRFREMLFGRDLEGILALAREQVEEGAHALDLSVAWTGRDELEDLQWLLPHLATAVTVPFMVDSTSPEAME
LALKHLPGRVLLNSVNLELEKFDRVASLAKAHGAALVALTIDEKGMAKTRAEKVRVALRMYERLTHHGFRPEDLLLDLLTFPITQGDEEARETLLAMEEL
KERLGVGFILGISNVSFGLKARRVLNSVFLDEARKRGLTAAIVDAGKILPIAQIPALDLIHDRRDPLFAFMAYFEAHREDV----GA--KEASALPLLER
LKRRVVEGRKGGLEADLEEALKAGHRPLDLINGPLLEGMKEVGELFGAGKMQLPFVLQAAEVMKRAVAFLEPHMEKRG-E-GKGKMVLATVKGDVHDIGK
NLVDIILTNNGYQVINLGIKVPIEEMLKAVEEHRPHALGMSGLLVKSTVVMKENLEYMAERG-TLPVILGGAALTRAYVEEPN-VYYAEDAFEGLRLMEE
LT-
>tr|Q72L12|Q72L12_THET2 5-methyltetrahydrofolate-homocysteine methyltransferase OX=262724 OS=Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039). GN= PE=3 SV=1
---YLKALLE-RPLVFDGAMGTELQKRDLTPGGCPEVLNRTRPEVVREIHLAYLEAGAEVIETNTFGALRHVLAEGLAAEELAFLGARIAREAADP--FV
AGALGPGTKLVS-LGQISWDALYRAYKEAARGLLKGGVDLILLETAQDILQVRCAVLAVREAREVPLQVQVTFETGTMLVGTDEQAALAALESLPVDVVG
MNCATGPDLMDSKVRYFAEHSTRFVSCLPNAGLPRN-EGGRVVYDLTPEELAKWHLKFVEYGVNAVGGCCGTGPEHIRKVAEAVKGLAPKPRPE--SFPP
QVASLYQAVSLKQEASLFLVGERLNATGSKRFREMLFARDLEGILALAREQVEEGAHALDLSVAWTGRDELEDLRWLLPHLATALTVPVMVDSTSPEAME
LALKYLPGRVLLNSANLELERFDRVASLAKAHGAALVVLAIDEKGMAKTREEKVRVALRMYERLTHHGLRPEDLLFDLLTFPITQGDEEAKETLLAIEEL
RERLGVGFVLGVSNVSFGLKARRVLNSVFLDEARKRGLTAAIVDAGKILPISQIPALDLIYDRRDPLLAFMAYFEAHKEDP----GK--REALALPLLER
LKRRVVEGRKQGLEADLEEALKAGHKPLDLINGPLLAGMKEVGDLFGAGKMQLPFVLQAAEVMKRAVAYLEPHMEKKG-E-GKGTLVLATVKGDVHDIGK
NLVDIILSNNGYRVVNLGIKVPIEEILKAVEAHKPHAVGMSGLLVKSTLVMKENLEYMRDRG-TLPVILGGAALTRSYVEEPN-VYYAEDAFEGLRLMEE
LT-
>tr|C7MUL0|C7MUL0_SACVD Methionine synthase (B12-dependent) OX=471857 OS=NBRC 12207 / P101). GN= PE=3 SV=1
---FLTELDR-RVLVADGGMGTALQGFDLTLQGCNEVLNDTRPDVVTAVYRSFLEAGSDAIETNTFGTNYGNFGEGIRIRELAEKGTVLARQCADEPRFV
LGSMGPGTKLPT-LGHAPYAVLRDAYVENALGMLDGGVDAVLVETSQDLLQAKAAIVGAKRARRVPIIAQVTVETGTMLVGSEIGAALTALEPLGIDLIG
MNCATGPAEMSEHLRVLSEHARVPISVMPNAGLPEL-GPDGAVYPLRPDELAEALATFVEFGVRLVGGCCGTTPEHVRAVVEAVSSLRPKERRP--EHTP
AVSSVYQSVPFKQDASILNVGERTNANGSKAFRQAMLEGRYDDCVEIAKAQTREGAHVLDLCVDYVGRDGTTDMAELASRLATASTLPIMVDSTEPEVVR
TGLEHFGGRCAINSVNYETSRYRRVLELAVEHGAAVVVTCIDEEGQARTAEWKLRVAERAISDLTNWGLDKSSIIIDCLVFPITTGQEEALETINAIRQL
KRRHDVMTTLGLSNVSFGLNARQVLNSVFLHECREAGLDSAILNSSKILPMNKIEALDLVYDRRDPLQRLMQLFEGKTASS----ARASRAEAKLPLFER
LEKRIVEGETTGLEEDLDAAMREK-KPIDIINEHLLAGMKVVGDLFGSGQMQLPFVLQSAETMKAAVAYLEPHMEKTD-ADGKGKLLLATVKGDVHDIGK
NLVDIIVSNNGYDVVNIGIKQPINAILEAAEEHQVDAIGMSGLLVKSTVVMKENLQEMNARGVKYPVLLGGAALTRTYVENEGDVRYAKDAFEGLKLMDR
IM-
>tr|I7DQ18|I7DQ18_AMYMD 5-methyltetrahydrofolate--homocysteine methyltransferase OX=713604 OS=Amycolatopsis mediterranei S699. GN= PE=3 SV=1
---FLEALRS-RVLVADGAMGTALQAHDLSLGGCNEILNVTRPDVVRSVHRGYLEAGADAVETNTFGANFANFAEDIRIFELAEAGARLARETADEPRFV
LGSVGPGTKLPT-LGHAPFTTLRDAYQEEVRGLLAGGADAVIVETTQDILQTKASIIGAKRARFVPILASITVETGTMLLGTEVGAALAALEPLGIDVIG
LNCATGPAEMSEHLRQLAKHARVPLSVMPNAGLPEL-GPDGAVYPLGPEALVEALTGFVEFGVGLVGGCCGTTDEHIRQLAAAVADTPPVPRRP--RPEP
GVSSLYQAVPFKQDASVLMIGERTNANGSKAFRTAMLEGRWDDCVEIAREQTRDGAHLLDLCVDYVGRDGTADMAELAGRLATASTLPIMLDSTEVPVLR
AALQRLGGRCAVNSVNYEDSRFAQVMELVSEYGAAVVALTIDEEGQARTAQKKADIATRLIEDITNWGLRTSDVIIDALTFTIATGQEEGIETIEAIREI
KRRHEVQTTLGLSNISFGLNARQVLNSVFLHECVQAGLDTAIVHASKILPMARIPALDLIHDRRDPLQELMALFEGVSAAS----SKASRAEAALPLFER
LERRIVDGERTGLTDDLDAALEQR-PALEIINDTLLSGMKTVGELFGSGQMQLPFVLQSAEVMKAAVAHLEPHMETGD-DSGKGRIVLATVRGDVHDIGK
NLVDIILSNNGYEVVNLGIKQPITTILDAAEEHGADAIGMSGLLVKSTVIMKENLQEMNSRGVRWPVLLGGAALTRSYVENLGDVRYARDAFEGLRLMDA
LM-
>tr|A0ZGY7|A0ZGY7_NODSP 5-methyltetrahydrofolate--homocysteine S-methyltransferase OX=313624 OS=Nodularia spumigena CCY9414. GN=N9414_16539 PE=3 SV=1
---HLHSPNR-PVIVFDGAMGTNLQSQNLTAGGCNEYLVHTNPEAVAKVHRDFLAAGADVIETDTFGATSIVLAEDLQTYYLNKTAVEIAKRVAAEPRFV
AGSLGPTTKLPT-LGHIDFDTLKANFAEQAEALFDGGVDLFLVETCQDVLQIKAALNGIEEVDRRPLMVSVTMEMGTMLVGSEINAVLTILAPYPIDILG
LNCATGPDLMKPHIKYLSEHSPFIVSCIPNAGLPEN-VGGQAHYRLTPMELRMALMHFVDLGVQVIGGCCGTRPEHIQQLAEISKTLKPKIRQH--SLEP
AAASIYSTQPYDQDNSFLIVGERLNASGSKKCRDLLNAEDWDGLVSMARAQVKEGAHILDVNVDYVGRNGVRDMHELVSRIVNNVTLPLMLDSTEWEKME
AGLKVAGGKCLLNSTNYEEPRFLKVLDLAKTHGAGIVIGTIDEDGMARTAERKFQIAQRAYRQAVEHGIPPTEIFFDTLALPISTGIEEGKATVESIRRI
RQELGCHVILGISNISFGLNSRVVLNSMFLHEAMQAGMDAAIVSPNKILPLSKIECLDLIYDRRDPLGELTTLFEGVTT-------KRDKGDS-LPLEER
LKRHIIDGERIGLEKLLTTALEQ-YPPLQIINTFLLDGMKVVGELFGSGQMQLPFVLQSAETMKTAVAYLEPFMEKSETSNGKGTFIIATVKGDVHDIGK
NLVDIILTNNGYRVINLGIKQPVENIIQAYEEHKADCIAMSGLLVKSTAFMKDNLQAFNEKGITVPVILGGAALTPKFVHQKGKVVYGKDAFSDLHFMDK
LM-
>tr|B7KCS9|B7KCS9_CYAP7 Methionine synthase OX=65393 OS=29155)). GN= PE=3 SV=1
---RLHSPER-PVLVFDGAMGTSLQTQNLTAGGCNEYLVHTKPEAVEKVHRGYLEAGADVIETDTFGGTSIVLAEDLKAYYLNKTAAQLAKRVAQEPRFV
AGSMGPGTKLPT-LGHIDFDTLKNAYIEQAEGLYDGGADLFIVETCQDVLQIKAALNAIEEVNRIPIMVSITMEMGTMLIGTEIGAALTILEPYNIDILG
LNCATGPDQMKEHIKYLSENSPFIISCIPNAGLPEN-VGGQAHYRLTPLELRMALMHFVDLGVQIIGGCCGTRADHIKALAEITKDLKPKERHP--HYEP
SAASIYSPQPYIQDNSFLIVGERLNASGSKKCRELLNKEDWDSLVSMAKSQVKEGAHILDVNVDYVGRDGVKDMKELASRLVNNVTLPLMLDSTEWEKME
AGLKVVGGKCILNSTNYEEPRFYQVLDLAKKYGAGVVVGTIDEEGMARTAEKKFAIAKRAYEAAVNYGLPPEEIFFDPLALPISTGIEEGKATIEAIKRI
RDELKCHILLGVSNISFGLNARQVLNSVFLHECMGVGLDSAIVSASKILPLAKIDCRDLIYDRRDPLTKLTEVFAGKTT-------KKTASKS-LPIEER
LKQHIIDGERIGLDDALAEALKQ-YPPLEIINTFLLDGMKVVGELFGSGQMQLPFVLQSAQTMKAAVAYLEPFMEKEEGGNTKGKFIIATVKGDVHDIGK
NLVDIILSNNGYTVINLGIKQPVENIIQAYQEHQADCIAMSGLLVKSTAFMKENLEVFNERGITVPVILGGAALTPKFVHEKGQVIYGKDAFSDLHFMDK
LM-
>tr|K9Z5I4|K9Z5I4_9CHRO Methionine synthase (B12-dependent) OX=755178 OS=Cyanobacterium aponinum PCC 10605. GN=Cyan10605_2363 PE=4 SV=1
---RLHSSDR-PVLVFDGAMGTNLQVQNLTAGGCNEYLVHTKPEAVETVHRGFLEAGADVIETDTFGGTPLVLAEDLRSYYLNKTAAQLAKRLADEPRFV
AGSMGPGTKLPT-LGHIDYDTLKNAYVTQVQGLYDGGVDLLLVETCQDVLQIKAALNAIEEVERLPLMVSVTMEMGTMLVGTEINAALTILERYPIDIMG
LNCATGPDLMKPHIKYLSENSPFVVSCIPNAGLPEN-VGGQAHYRLTPIELRMALMHFIDLGVQIIGGCCGTRYEHIRALAEIASTLKPKQRQY--HYEP
SAASIYTTQPYQQDNSFLIVGERLNASGSKKCRDLLNAEDWDGLISLAKAQVKEGAHILDVNVDYVGRDGVKDMHELASRLVNNVTLPLMLDSTEWQKME
AGLKVAGGKCILNSTNYEEERFFKVLELAKEYGAGVVIGTIDEDGMARTADKKVEIAQRAYNDAVKFGIPAHEIFFDTLALPISTGIEEGKATIESIQRI
HAMFECHFMLGVSNISFGLNARQVLNSVFLHEAMQVGMDGAIVSASKILPLAKIDCRDLIYDLRDPLGKLTTLFEGKTT-------KSNKKVD-LPIEER
LKQHIIEGERIGLEDALKIALEK-YPPLDIINVFLLDGMKVVGELFGSGQMQLPFVLQSAQTMKAAVAFLEPFMDKADSGSGKGTFLIATVKGDVHDIGK
NLVDIILSNNGYKVINLGIKQPVENIIQAYRESNADCIAMSGLLVKSTAFMKDNLETFNQEGITVPVILGGAALTPKFVYEKGKVVYGKDAFADLHFMDK
LM-
>tr|K7R622|K7R622_THEOS 5-methyltetrahydrofolate--homocysteine methyltransferase OX=751945 OS=Thermus oshimai JL-2. GN=Theos_1344 PE=4 SV=1
---YLKALSE-RVLVFDGAMGTELQKLDLTPGGCPEILNATRPEVVQAIHRAYLEAGAEVIETNTFGALRHVLAEGLRAEELARRGAELAKEVARP--FV
AGALGPGTKLIS-LGQITWEELYAAYKEAARGLLLGGVDLILLETAQDILQVRCAVLAVREAREVPLQVQVTMETGTMLVGTDEAAALAALESLPIDVVG
MNCATGPDLMDSKIRYFAEHSTRFVSCLPNAGLPRN-EGGRVVYDLTPEELARWQRKFVDYGVNAVGGCCGTGPAHIRALAEAVRGLPAPKRPP--AFPP
QVASLYQAVPLRQEASLFLIGERLNATGSKRFREMLFAGDLEGILALAREQVAEGAHALDLSVAWTGRDELKDLRWLLPHLATAVTVPLMVDSTSPEAME
LALHHLPGRVLLNSANLELPRFDRVASLAKAHGAALVALAIDEEGMAKTRARKVEVALRMYQRLTHHGLRPEDLLFDLLTFPITQGDEEARETLEAIEEL
AGRLGVGFVLGVSNVSFGLKARRVLNSVFLDEARKRGLTAAIVDAGKILPIHEIPALDLIYDRRDPLLAFMAYFEAHQEDP----AK--REALALPLLER
LKRRIVEGRKVGLEADLDEALRAAHKPLDLINGPLLAGMKEVGELFGAGKMQLPFVLQAAEVMKRAVAHLEPHMEKRG-A-GKGVMVLATVKGDVHDIGK
NLVDIILTNNGYRVVNLGIKVPIEEMLKAVEEHKPHALGMSGLLVKSTQVMKENLEYMAERG-TLPVILGGAALTRAFVEEPN-VYYAEDAFEGLRLMEE
LT-
>tr|F5UL57|F5UL57_9CYAN Methionine synthase OX=756067 OS=Microcoleus vaginatus FGP-2. GN=MicvaDRAFT_4859 PE=3 SV=1
---RLHHPSR-PVIVFDGAMGTNLQVQNLTAGGCNEYLVHTKPEAVANVHRGFLEAGADVIETDTFGAASIVLAEDLKAYYLNKTAAELAKGIAAEPRFV
AGSIGPGTKLPT-LGHIDFDTLTAAFAEQAEGLYDGGVDLFIVETCQDVLQIKSALNAIEEVARIPLMVSVTMETGTMLVGSDISAALAILQPYPIDILG
LNCATGPDRMAEHVKYLSEHSPFVVSCVPNAGLPEN-IGGHAHYKLTPIELKMALMRFVDLGVQVIGGCCGTRYDHIRELAEIGKTLKPKIR--EITWEP
SAASIYSAQPYEQENSFLIVGERLNASGSKKCRDLLNAEDWDGLVAMAREQVREGAHILDVNVDYVGRDGVRDMKELVSRVVTNATLPLMLDSTEWEKME
AGLKVAGGKCLLNSTNYEEPRFYQVLELAKKYGAGIVIGTIDEDGMARTADQKFAIAQRAYNAAVAYGIPAEEIFFDTLALPISTGIEEGKATIESIRRI
RQELGCHVILGVSNISFGLNARQVLNSMFLHEAMQAGMDSAIVSANKILPLAKIDCRKLIYDERDPLGDLTTVFAGKTT-------KRDRTDS-LPVEER
LKQHIIDGERIGLDIQLAKALES-YPPLHIINTFLLDGMKVVGELFGSGQMQLPFVLQSAETMKAAVAYLEPHMEKSESDNAKGTFIIATVKGDVHDIGK
NLVDIILSNNGYRVINLGIKQSVDNIIEAYEKHKADCIAMSGLLVKSTAFMKENLEVFNQKGITVPVILGGAALTPKFVHEKGKVVYGKDAFSDLHFMDK
LM-
>tr|Q7VBY3|Q7VBY3_PROMA 5-methyltetrahydrofolate--homocysteine methyltransferase OX=167539 OS=Prochlorococcus marinus (strain SARG / CCMP1375 / SS120). GN= PE=3 SV=1
---YINSSKS-SVLVFDGAMGTSLQSLNLTAGGCNENLVLTNPQAVRNVHRSYLEVGCDVIETNTFGATSIVLEENLKTYEINLEAARLAKGIVKEPRFV
AGSVGPTTKLPT-LGHISFDKLSSSYQEQIEALIDGEVDLILLETCQDVLQIKSALVGINNAKYLPIMVSVTMETGTMLLGTDISAVVNILAPFNIDILG
LNCATGPHEMKRHIEYLSEYSPFLISCIPNAGLPEN-IGGKAHYRLTPIELKMQLSHFIDLGVKVIGGCCGTGPTHIEQLVKLSQEVIDTIEQKEKNTDY
GVSSLYEMTSYNQDQSILIIGERLNASGSRKVRELLNENNWDGLIAVAKDQLKEQAHVLDVNVDYVGRDGVEDMSKVVSQLVTNINLPLMLDSTDYTKME
SGLKNAGGKCILNSTNYEPERFYKVLDLCKKYGSAVVIGTIDENGMARTSDLKIKIAERSFNDATKYGIAEFDIFYDPLVLPISTGLEEASETIKAISIL
RKRFHVHITLGISNVSFGLNARITLNSVFLEECIVAGLDSAIISPAKILPTQKIKCIDLIYDKRDPLTELTSLFSDVTSQS----LKQRTDLS-LPLEER
LKKHIIDGEKNDLREHLLVALDD-YKALDIINNFLLDGMKVVGELFGSGKMQLPFVLQSAETMKYAVSVLEPYMETES-VQSKGKFIIATVKGDVHDIGK
NLVDIILTNNGYDVINLGIKQDISEIINAQKKFQADCIAMSGLLVKSTAFMKDNLQELNNNLISIPVILGGAALTPKFVNQKGQVIYGKDAFTDLTFMDA
YM-
>tr|Q46L03|Q46L03_PROMT Methionine synthase (B12-dependent) OX=59920 OS=Prochlorococcus marinus (strain NATL2A). GN= PE=3 SV=1
---YLNSEKR-PIIVFDGATGTSLQDQQLTAGGCNENLVLTSVSSVEKVHQSFLEAGCDVIETNTFGATSIVLDEGIKAYEINFKAAQIARSIANKPRFV
AGSIGPTTKLPT-LGHISFDELKKSYLEQAKALIEGGIDLFLIETCQDVLQIKAALQSVNEAIKIPVMVSVTMETGQMLIGSDISSITTILEPFNIDILG
LNCATGPEEMKDHIKYLSEHSPFHISCIPNAGLPEN-VGGKAHYRLTPMELKFQLSHFIDLGVQLIGGCCGTRPEHIKQLSDLSLELLSSDRRLIKERSP
AASSIYESIPYEQDNSFLIVGERLNASGSKKVRELLNIEDWDGLVGIAKSQLKENAHVLDVNVDFVGRNGIEDMSNLVKRLVNNINLPLMLDSTDYEKME
SGLKHAGGKCILNSTNYEQDRFHKVIDLAKEHGSAVVIGTIDEDGMARSAEKKAEIATRAFKDATNSGLKPYEIFYDPLALPISTGLEEGFETIKAIKLI
KDRHQVHLILGISNVSFGLSARVVLNSIFLNEAIKAGLDSAIVSPSKILPLNKISCLDLIYDKRDPLTTLTSYFDDSKKLL----NNSSIDDN-LPIEDK
LKNHIIDGEKTNLHSNLDLALNK-YKPLVIINEYLLDGMKVVGELFGSGQMQLPFVLQSAETMKYAVSYLEDFMDKEV-NQSKGKFIIATVKGDVHDIGK
NLVDIILSNNGYDVINLGIKQDVNAIINAQKEHHADCIAMSGLLVKSTAFMKDNLKALNEEDIDVPIILGGAALTPKFVNQKGKVIYGRDAFTDLKFMDA
YM-
>tr|C0QRY9|C0QRY9_PERMH Methionine synthase OX=123214 OS=Persephonella marina (strain DSM 14350 / EX-H1). GN= PE=3 SV=1
---IRDLIGK-KVLVIDGAMGTMIQSMIIPMGGCNEILNVTAPDVIRSIHEKYALAGADLIKTNTFGALPWVLEEGIRAYELSKAGAELVRQVCDKPRFV
AGSLGPGTKLPS-LGHIDYDEMYEGYRISAKGLIDGGVDIFLLETFQDPLQIKAALHAVQDTKDIPVMVSATIETGTMLIGTDVQTLAVIMEPFDILTLG
FNCGTGPDQIESHLKKLSQVWDGYISIHSNAGLPEN-RGGHTYYPMGAEEFADKESRFLFDGVAVVGGCCGTTPAHIKALAEKVKDKKPKPPKG--NQ-P
RLASLYGIQPLKQEPPPFLVGERTNATGSKKFRELLLSEDYDGILSVAQDQVKAGAHALDVSVNFAGRDEIKDMKAVISRFNEKIPIPLMPDSTQPSALE
TALKCIGGRPILNSANLEEERFNRICQLAKRYGAALVLLTIDEKGMAKTKERKVEIAERMYRIATKHGINPGDLVFDVLTFTVGSGDEEAVHTIEAIKEI
KEKHEVGFVLGISNVSFGLDARKYLNSVFLHHCVEAGLTMAIINPKHLIPYYRISCENLLFNIWDPLFRFIQHFSKTERKD----TGEDQDS--LPVEER
IKKLLIDGEKEKLIKTVEEARHS-IPPEKIINEVLIDAMKVVGDLFGEGKMQLPFVLQSAEAMKAAVDYLNQYLPKKK-KEKETTLILGTVKGDVHDVGK
NLVDIILTNNGFKVVNIGIKAELEDFIKAYKEHNADAIGMSGLLVKSTLEMKNNLEEMRKRGINVPVLLGGAALNKSFVDQDGPVFYCRDAFDGIEAMSR
IL-
>tr|H5WZU0|H5WZU0_9PSEU 5-methyltetrahydrofolate--homocysteine methyltransferase OX=882083 OS=Saccharomonospora marina XMU15. GN=SacmaDRAFT_3664 PE=3 SV=1
---FLAELQR-RVLVADGGMGTALQEHDLTLQGCNEILNETRPDVVASVYRGFLEAGSDAIETNTFGTNLANFAEDIRIRELAEKGTSLARQCADEPRFV
LGSIGPGTKLPT-LGHITFAELRDAYVDNALGLLDGGADVVLVETSQDLLQTKAAIIGAKRARTVPVIAQVTVETGTMLVGSEIAAALTALEPLGIDLIG
MNCATGPAEMSEHLRVLSDHARVPISVMPNAGLPEL-GPNGAVYPLRPDELAEALAGFVEFGARLVGGCCGTTAEHVRAVREAVADLSPKVRTP--EIVP
SVSSVYQSVPFRQDASILNVGERTNANGSKAFRDAMLEQRWDDCVEIAKSQTREGAHMLDLCVDYVGRDGTADMSELASRLATASTLPIMVDSTEAEVVR
AGLERFGGRCAINSVNYETGRYDEVMRLAVEHGAAVVITCIDEEGQARTAEWKLRVAERAIEDLTNWGMDKSSIIIDTLVFPITTGQEEALETINAIREL
KRRHDVQTTLGLSNVSFGLNARQVLNSVFLNECREAGLDSAIVNSSKILPMNKIDALDLVYDRRDPLQKLMSLFEGKTASS----TRASRAEAKLPLLER
LEKRIIEGELNGLEDDLEAAMREK-DPLAIINENLLAGMKVVGELFGSGQMQLPFVLQSAEVMKTAVAYLEPYMEKDD-SGGKGKLLLATVKGDVHDIGK
NLVDIIVSNNGYDVVNIGIKQPINAILDAADEHKVDAIGMSGLLVKSTVIMKDNLKEMNARGVKYPVLLGGAALTRTYVENDGDVRYAKDAFEGLRLMDH
VM-
>tr|G4IZJ5|G4IZJ5_9PSEU Methionine synthase OX=882084 OS=Saccharomonospora paurometabolica YIM 90007. GN=SacpaDRAFT_1420 PE=3 SV=1
---FLDELQR-RVLVADGGMGTALQEYDLTLQGCNEILNETRPDVVRSIYRGFLEAGSDAIESNTFGTNYGNFGEDIRCRDLAEKGASLARECADEPRFV
LGSMGPGTKLPT-LGHAPYALLRDYYQENALGLLDGGADAVLVETSQDLLQTKAAIVGAKRARRIPIIAQVTVETGTMLVGSEIGAALTALEPLGIDMIG
MNCATGPAEMTEHLRVLAEHATVPISVMPNAGLPEL-GENGAVYPLQPDELAASLKEFVDFGARLVGGCCGTTGEHVRAVVDAVSDLTPKEREP--EVVP
SVSSVYQAIPFEQEASLLNVGERTNANGSKAFREAMLEQRYDDCVEIAKAQTREGAHLLDLCVDYVGRDGTEDMIELASRLATSSTLPVMVDSTEADVIE
AGLERFGGRCAINSINYETGRYDRVMKMAVEHGATVVVTCIDEEGQARTADWKLRVAERAITDLTNWGLDESAVIIDLLVFPITTGQEEGIETINAIREL
KKRHRVQTTLGLSNVSFGLNARQVLNSVFLNECREAGLDSAIVNSSKILPMNKIEALDLVYDRRDPLQKLMGLFEGKTASS----NQASRAEAKLPLFER
LQKRIIDGELNGLHADLDEAMQEK-KPLQIVNEDLLAGMKVVGDLFGSGQMQLPFVLQSAEAMKTAVAHLEPHMEKDD-SGGKGKLLLATVKGDVHDIGK
NLVDIIVSNNGYDVVNIGIKQPINAILEAAEEHEVDAIGMSGLLVKSTVIMKDNLQEMNSRGVKFPVMLGGAALTRTFVENEGEVHYAKDAFEGLTLMDR
IM-
>tr|D4ZXI4|D4ZXI4_SPIPL 5-methyltetrahydrofolate--homocysteine methyltransferase OX=696747 OS=Arthrospira platensis NIES-39. GN= PE=3 SV=1
---RLHSPQR-PVIIFDGAMGTNLQVQNLTAGGCNEYLVHTKPEAVATVHRQFLQAGADVIETDTFGGTSIVLAEDLQAYQLNQTAATLAKSVAAEPRFV
AGSMGPGTKLPT-LGHIDFDTLERAFCQQAEGLFDGGVDLFIVETCQDVLQIKAALNGIEEVERRPIMVSVTMEFGTMLVGSEINAALTILEPYQIDILG
LNCATGPDLMKEHIAYLSEHSPFVVSCIPNAGLPEN-VGGQAHYKLTPLELKMALMHFIDLGVQVIGGCCGTRPDHIKALAEIAQTLTPKPRHP--QITP
SAASIYSTISYEQENSFLIVGERLNASGSKKCRDLLNAEDWDGLVALAKTQVKEGAQILDVNVDYVGRNGVRDMHELVSRLVTNVNLPLMLDSTEWEKME
AGLKVAGGKCLLNSTNYEEPRFYKVLELAKKYGAGVVVGTIDEEGMARTAAKKFAIAQRAYNDAIAFGIPATEIFFDPLALPISTGIEEGKATIEAIHQM
RQQLGCHILLGISNISFGLNARQVLNSVFLHETMAVGLDAAIVTANKILPLAKIECHHLIYDQRDPLTKLTTLFEGKTT-------KRDRSDN-LPIEER
LKQHIIDGERIGLEDALAEAIKK-YPPLDIINIFLLDGMKVVGELFGSGQMQLPFVLQSAQTMKAAVAYLEPFMEKSESNNAKGTFVIATVKGDVHDIGK
NLVDIILSNNGYKVVNLGIKQPVDNIISAYREHNADCIAMSGLLVKSTAFMKDNLEVFNQEGITVPVILGGAALTSKFVYEKGRVIYGKDAFSDLTFMDK
LM-
>tr|C7R4L4|C7R4L4_JONDD Methionine synthase OX=471856 OS=(Listeria denitrificans). GN= PE=3 SV=1
---LRQALTH-RVVVADGAMGTMLQAASLTLGGCNEILNVTVPDVIESIHDAYFAVGVDCVESNTFGANWSNLSDEIRIYELAYAGASIARRSADRDTWV
LGSMGPGTKLPS-LGHTTYAHLKTTFTQQALGLLDGGADAFLIETAQDILQAKAAINACHAAKRILIMVSVTVETGTMLMGSEIGAALTALSALNIDSIG
LNCATGPAEMSEHLRHLSKHAPIPVTCMPNAGLPVL-GKNGAEYPLTPTELAAAHRQFVEFGLGLVGGCCGTTPEHLGAVVAAVRDTSPAKRTV--TVEN
GVASLYSHTDFHQDSSFLAIGERTNANGSKAFREAMLAENWDECVTIARSQTRDGAHVLDVCVDYVGRDGVADVTNVVSRLASASTLPLVIDSTEPDVIK
AALELIGGRPVVNSVNFEDSRYARIMPLVKEHGAAVVALTIDEEGQARTRDAKVAIATRLITDLTRWGMSVTDIIVDTLTFPIATGQEEAIETIHAIKDI
TTAFGIHTTLGVSNVSFGLSARHVLNSVFLHEAVAAGLDSAIVHAAKIMPLKNIPALDLIWDRRDPLAHFLNVFSGVDAAS----LNQSRAEAALPLTER
LERRIIDGDNKGLTGDLDQALSQG-SALDIINDHLLAGMKVVGDLFGRGEMQLPFVLQSAETMKAAVAWLEPHMERTE-SAGKGTMVLATVRGDVHDIGK
NLVDIILTNNGYNVINIGIKQSINAMIEAAEEHNADVIGMSGLLVKSTVVMKENLEELNSRGLKYPVLLGGAALTRVYVEDDGVVRYARDAFEALRLMDS
LV-
>tr|B1XKG9|B1XKG9_SYNP2 5-methyltetrahydrofolate--homocysteine methyltransferase (Methionine synthase) OX=32049 OS=quadruplicatum). GN= PE=3 SV=1
---RLNSPER-PVLVFDGAMGTNLQVQNLTAGGCNEYLVQTKPEAVATVHRAFLAAGADVIETDTFGGTSIVLAEDLRAYELNKKAAELAKSVTAEPRFV
AGSIGPGTKLPS-LGHIDYDTLENAFAEQAEGLYDGGADLMLVETCQDVLQIKAALNGIERTDRLPIMVSVTMEMGTMLVGTEIAAAVAILEPYRIDILG
LNCATGPDLMKEHVKYLSEHSPFIVSCIPNAGLPEN-VGGQAHYKLTPLEMKMAMMHFVDLGVQVIGGCCGTRPEHIQALAEIAAELTPKERHP--DYEP
AAASIYSPQPYIQDNSFLIVGERLNASGSKKCRTLLNEEDWDSLVSLAKSQVKEGAHVLDVNVDYVGRDGVRDMHELASRLVNNVTLPLMLDSTEWEKME
AGLKVAGGKCILNSTNYEEERFYQVLSLAKKYGAGVVIGTIDEEGMARTAEKKFEIAKRAYDAAIAYGLPAHEVFFDPLALPISTGIEEGQATLDAIERI
HKELGCHIILGVSNISFGLNARQVLNSVFLHDAMQLGMDSAIVSASKILPMAKIDCRDLIGDRRDPLTKLTELFAGKKA-------KKSEADN-LPVNER
LKQHIIDGERLGLEEALTEALEQ-YPPLDIINIFLLDGMKVVGELFGSGQMQLPFVLQSAQTMKAAVAFLEPYMDKEEGDSGKGTFIIATVKGDVHDIGK
NLVDIILSNNGYKVINLGIKQPVENIIQAYEENGADCIAMSGLLVKSTAFMKDNLEAFNEKGITVPVILGGAALTPKFVYQKGQVIYGKDAFADLHFMDK
LM-
>tr|A9B073|A9B073_HERA2 Methionine synthase OX=316274 OS=Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785). GN= PE=3 SV=1
---YIAELAK-RVLIYDGAMGTSLDLYDLKPGGARDYLALTRPDIIEQIHSSFMEAGVDVLETNTFQSTRIRLHEGLKTYEQNFKAAQLARKVADRKRFV
AGSMGPTGFLPSSLSNITWDALSDTFKEQTIALVEGGVDVLLVETSVDILEVKAAIDGIRRGRDIAIQAQVFLDSGRMLLGTDIQATMVTLEALAVDVIG
LNCSTGPEHMRPAITYLAANSKLPISCIPNAGLPME-VNGETVFPLEPAGFAKSLTEFVDLGVRVVGGCCGTTPAHLRALVDSI-GNNPKPNQA--PI-P
QVSSAMRSLALHQDPGPFIIGERVNSVGSRKVKKLLLKDDYDGVLQIAREQADSGSHALDVCVAMTERDEKEQMQKLLKKLTMGVELPLVIDSTEYEVID
AALQIYPGRAIINSTSLERQKFDKTMPLVARYGAAIIALTIDEEGMAHTAEAKVAIAKRMAEMGREYGVQNDAWLFDALTFPLTTGQAEAKETMEGIRRI
KAEIGAMTVLGVSNLSFGIQARSALNSVFLYHAVKAGLDAAIINPTHVMPFAEISCEDVIFNSDEALPRFIQYFETAVAGE----AKVDPTAT-MNAEER
IHWKILHRKKDGIEADIDESRQGE-AAIDILNGVMLPAMKEVGDKFGAGELILPYVLQSAEVMKRAVAHLEQFLDRVE---GKGKVVLATVYGDVHDIGK
NLVYTILSNNGYTVYDLGKQVPVNTIIEKALEVGADAIGLSALLVSTSKQMPLCVQELHKRNLAFPVLVGGAAINRQYPEPTGGVFYCKDAFEGLETMDK
LS-
>tr|K9R9L2|K9R9L2_9CYAN Methionine synthase (B12-dependent) OX=373994 OS=Rivularia sp. PCC 7116. GN=Riv7116_1571 PE=4 SV=1
---HLRSPKR-PVVVFDGAMGTNLQVQELTAGGCNEYLVHTKPEAVATVHRGFLAAGADVVETDTFGGTSIVLAEDLQAYYLNKAAAELAKKVCAEPRFV
GGSMGPGTKLPT-LGHIDFDTLKNAYVEQAEALWDGGVDLFIVETCQDVLQIKSALNAIEEVDRRPIMVSVTMEMGTMLVGTEIAAVVTILEPYNIDILG
LNCATGPDLMKPYIKYLSEHSPFIVSCIPNAGLPEN-VGGQAHYKLTPVELKMHLMHFIDLGVQAIGGCCGTRPKHIEALAEIAKDLTPKDRKP--QTEP
AAASIYGTQPYDQDNSFLIIGERLNASGSKKCRTMLNDEDWDGLVSLGRSQVKEGAHVLDVNVDYVGRDGVRDMHELVSRLVNNITLPLVLDSTEWEKME
AGLKVAGGKCLLNSTNYEEERFLKVLELAKTYGAGVVIGTIDEDGMARTADKKFEIAQRAYRQALEYGIPAHEIFFDNLALPISTGIEEGKATIESIRRI
RQELGCHVVLGVSNVSFGLNARIVLNSMFLHEAMQAGMDAAIVSASKILPLAKIECRDLIYDNRDPLGELTTMFEGVSA-------KRDKGDS-LPIEER
LKQHVIDGERIGLEDALKEAMEK-YPPLDIVNIYLLDGMKVVGELFGSGQMQLPFVLQSAETMKAAVAFLEPHMEKSEGDNAKGTFVIATVKGDVHDIGK
NLVDIILSNNGYRVINLGIKQPVENIIQAYEEHKPDCIAMSGLLVKSTAFMKDNLETFNEKGITVPVILGGAALTPKFVNDKGKVIYGKDAFSDLHFMDK
LM-
>tr|K5BFW4|K5BFW4_9MYCO Methionine synthase OX=1122247 OS=Mycobacterium hassiacum DSM 44199. GN= PE=4 SV=1
---MLDTLAK-RVVVGDGAMGTQLQAADLTLNGCNEILNETRPDVIERIHRAYFEAGADAVETNTFGCNISNLGDDIRIRDLSLRGTRIARRVADEKRYV
LGSMGPGTKLPT-LGHIEYTVVRDAYIEAALGMLEGGADAILVETCQDLLQLKAAVLGSRRARYIPIIAHVTVETGTMLLGSEIGAALTAVEPLGVDVIG
LNCATGPAEMTEHLRYLSQHARTPISVMPNAGLPVL-GANGAEYPLTPDELAEALSTFIEYGLSLVGGCCGTTPEHIRRVAEAVPGLRRAERNP--DHEP
ALSSLYTSVPFHQDASVLMIGERTNANGSKAFREAMLAEDWQRCLDIAKEQTRDGAHVLDLCVDYVGRDGVADMTALAGRLATASTLPIMLDSTETAVLR
AGLERLGGRCAVNSVNYEDSRFHKTMELVAEHGAAVVALTIDEEGQARTAEKKVEIAERLIADITNWGLDESSILIDTLTFTICTGQEEGIETIEAIREI
KRRHRVLTTLGLSNISFGLNARQVLNSVFLHECRQAGLDSAIVHASKILPMNRIDALDLIYDRRDPLQELMAMFEGVSAAS----SRESRAEAKLPVLER
LAQRIVDGERNGLEADLDEAMQLK-PPLDIINDNLLAGMKVVGELFGSGQMQLPFVLQSAEVMKAAVAYLEPHMEKKE-DDGKGRIVLATVKGDVHDIGK
NLVDIILSNNGYEVVNIGIKQPISTILEVAEDKRADVIGMSGLLVKSTVVMKENLEEMNLRGVKYPVLLGGAALTRGYVEDEGEVYYARDAFEGLRLMDR
IM-
>tr|H5SL33|H5SL33_9CHLR Methionine synthase OX=166587 OS=uncultured Chloroflexi bacterium. GN=HGMM_F44F02C10 PE=3 SV=1
---YLDALET-RVLIYDGAMGTNLQKMNLRAGGCNDYLVLTYPQAVETVHRSFLEVGVDVIETNTFRSNRITLAEGLKVIEINRAAASLARRLADEPRFV
AGSIGPSGKLPSALSNITFDELADVFREQAIGLIQGGVDVLLIETSQDILEVKAAIHGILRAIWLPIQAQVTLDTGRMLLGTDIQAALTILEGLPIDVIG
MNCSTGPEHMREPIRILGEQSRLPVSCIPNAGLPLN-VDGQAVYPLEPEPFAAALVEFVKHHINVVGGCCGTTPAHLKLLVEKL-HGRRPPRPI--LS-P
RLASAIQAVPMRQTPPPMLIGERCNAQGSRKFKQLLLAEDYDGILELAREQVNNGAHALDISTALTERDEAELMRKVVKKLSMGVEVPLVIDTTEVEVLE
VALKTAPGRCLINSTHLERTKADRVFRLAKEHNAAVICLTIDEQGMAKTRERKLEVAKRIYELAVEHGLPPESLVFDALTFTLATGDPEAIETLEGIRLI
KQNLGVLTSLGVSNLSFGLAARPVLNSVMLYHAVEAGLDMAIINPAHVTAYADIPAEDLIFNRRDALQRYIEYFERPQTSE----TAADPTSG-MTAPQR
LYWRIVHRHKEGVEADIDEIIRHA-AAVHILNNVLLPAMKEVGDKFGAGELILPFVLQSAEVMKRAVAHLETYLEKKE---GKGRIVLATVYGDVHDIGK
NLVKTILVNNGYEVIDLGKQVPAEKIIQTAVETQATAIGLSALLVSTSRQMPLIVNELHRRGLQFPVLIGGAAINRRFTESLPGVFYCKDAFEGLETMDA
LI-
>tr|G6FPR4|G6FPR4_9CYAN Methionine synthase OX=741277 OS=Fischerella sp. JSC-11. GN=FJSC11DRAFT_0844 PE=3 SV=1
---RLHSPER-PVIVFDGAMGTNLQRQNLVAGGCNEYLVHTKPEAVAKVHRDFLAAGADVIETDTFGGTSIVLAEGLKAYYLNKTAAQLAKRVAAEPRFV
AGSMGPTTKLPT-LGHIDFDTMKDAFAQQAEALWDGGVDLFIVETCQDVLQIKAALNGIEEVDRRPLMVSVTMEMGTMLVGTEINAVLTILEPYPIDILG
LNCATGPDLMKPHIKYLSEHSPFVVSCIPNAGLPEN-VGGKAHYRLTPMELRMSLMHFVDLGVQVIGGCCGTRPEHIQQLAEIAKELKPKVREP--KLEP
AAASIYSIQPYEQDNSFLIIGERINASGSKKCRELLNAEDWDGLVSMARAQVKEGAHILDINVDYVGRDGVRDMHELVSRIVNNVTLPLMLDSTEWEKME
AGLKVAGGKCLLNSTNYEEPRFLKVLELAKKYGAGVVIGTIDEEGMARTADKKFQIAQRAYRQALEYGIPAHEIFFDTLALPISTGIEEAKATIEAIRRI
RQELGCHVVLGVSNISFGLSARIVLNSMFLHEAMAAGMDAAIVSANKILPLAKIECRQLIYDERDPLAELTKMFEGVTT-------KRDKGDN-LPIEER
LKRHIIDGERIGLDIALAEALKK-YPALDIINIFLLDGMKVVGELFGSGQMQLPFVLQSAETMKAAVAYLEPFMEKSAADNAKGTFIIATVKGDVHDIGK
NLVDIILSNNGYRVINLGIKQSVESIIEAYEKHKADCIAMSGLLVKSTAFMKENLEVFNEKGITVPVILGGAALTPKFVYEKGKVVYGKDAFSDLHFMDK
LM-
>tr|C6WIB0|C6WIB0_ACTMD Methionine synthase OX=446462 OS=3971). GN= PE=3 SV=1
---LLDALTE-RVVVADGAMGTMLQSFDLSLGGCNEILNTTRPDVVRAVHRGYLEAGADAVETNTFGANLSNFSDGIRIFELSRLGAQLAREAADEPRFV
LGSVGPGSKLPT-LGHVAYSVLRDSYVEQIRGLLVGGSDAIIVETSQDLLQTKAAIVGARRALRVPIIAQVTVETGTMLLGSEIGAALTALEPLGIDLVG
LNCATGPAEMSEHLRHIAKHARIPLSVMPNAGLPQL-GPNGAVYPLGPEELAQALRGFAEFGARLVGGCCGTTAEHVRQVAAAVRDLGPTTRRP--RPEP
GVSSLYQAVPFQQDASVLMIGERTNANGSKAFREAMLADRWDDCVGIARDQTRDGAHLIDLNIDYVGRDGVADMSALASRLATASTLPIMLDSTEPEVLQ
AGLEHLGGRCAVNSVNYEDSRFQRIMRLVAEHGAAVVGLCIDEEGQARTAEWKVRVAIRIIEDLVNWGLRHGDIIIDCLTFPISTGQEEGVETIEAIREL
KRRYEVRTTLGLSNVSFGLNARQVLNSVFLHECVQAGLDTAIVHASKIVPMARIPALDLVYDRRDPLQRLMELFEGVTTSA----SKATRAEAALPLFER
LQRRIVDGERNGLEADLDEALTRR-PALQIINDTLLAGMKTVGELFGSGQMQLPFVLQSAEVMKTAVAHLEPHMERSD-DGGKGRIVLATVKGDVHDIGK
NLVDIILSNNGYEVINLGIKQPISAILDAAENHRADAIGMSGLLVKSTVIMKENLEEMNSRGVRWPVLLGGAALTRAYVENLGEVRYARDAFEGLRLMDA
VM-
>tr|B2J2H4|B2J2H4_NOSP7 Methionine synthase OX=63737 OS=Nostoc punctiforme (strain ATCC 29133 / PCC 73102). GN= PE=3 SV=1
---RLRSPDS-PVLVFDGAMGTNLQTQNLTAGGCNEYLVHTKPEAVAKVHRDFLAAGADVIETDTFGSTSLVLAEDLQAYYLSKTAAELAKRVAAEPRFV
AGSIGPTTKLPT-LGHIDFDTMKATFAEQAEALWDGGVDLFLVETCQDVLQIKAALNGIEEVDRRPLMVSVTMEMGTMLVGSEISAVLAILEPYPIDILG
LNCATGPDLMKPHIKYLSEHSPFIVSCIPNAGLPEN-VGGQAHYRLTPLELRMSLMHFVDLGVQVIGGCCGTRPEHIQQLAEVAKDLKPKVRQP--SLEP
AAASIYTTQPYDQDNSFLIVGERLNASGSKKCRDLLNAEDWDGLVSMARAQVKEGAHILDINVDYVGRDGVRDMHELVSRIVNNVTLPLMLDSTEWEKME
AGLKVAGGKCLLNSTNYEEPRFLKVLELAKKYGAGVIIGTIDEDGMARTADKKFAIAGRAYRQAVEYGIPPTEIFFDTLALPISTGIEEGKATIESIRRI
RQELGSHVILGVSNISFGLTSRMVLNSVFLHEATTAGMDAAIVSANKILPLSKIDCRQLIYDERDPLGELTTVFAGVTT-------KRDRSDS-LPIPER
LKRHIIDGERIGLEEHLKKALEE-HPPLEIINTFLLDGMKVVGELFGSGQMQLPFVLQSAETMKAAVAFLEPFMEKSESNNAKGTFIIATVKGDVHDIGK
NLVDIILSNNGYKVINLGIKQPVENIIKAYEQHKADCIAMSGLLVKSTAFMKENLEVFNEKGISVPVILGGAALTPKFVYEKGKVVYGKDAFSDLHFMDK
LM-
>tr|D4TN20|D4TN20_9NOST 5-methyltetrahydrofolate--homocysteine methyltransferase OX=533247 OS=Raphidiopsis brookii D9. GN=CRD_00798 PE=3 SV=1
---RLHSPEH-PVIVFDGAMGTNLQIQNLKAGGCNEYLIHTKPEAVAKVHRDFLLAGADVIETDTFGGTSIVLAEDLQAYYLSKKAAELAKRVAGEPRFV
AGSIGPTTKLPT-LGHIDFDTMKSAFAEQVTALFDGGVDLFIVETCQDVLQIKAALNGIEEVERRPVMVSVTMEMGTMLVGTEIAAVLTILAPYSIDILG
LNCATGPDLMKPHIKYLSEHSPFVVSCIPNAGLPEN-IGGQAHYKLTPLELRMALMHFVDLGVQVIGGCCGTRPDHIQQLAEIAKDLKPKVRQP--SLEP
AAASIYSTQNYTQDNSFLIVGERLNASGSKKCRDLLNTEDWDGLVSIARSQVKEGAHILDVNVDYVGRDGVRDMHELVSRVVNNVTLPLMLDSTEWEKME
AGLKVAGGKCLLNSTNYEEPRFLKVLELGKKYGAGVVIGTIDEEGMARTAQKKFEIAQRAYRQAVEYGIAPSEIFFDTLALPISTGIEEGSATIESIRRI
REELDCHVILGVSNISFGLNARIVLNSMFLHEAMGAGMDAAIVSASKILPLAKIDCKQLIYDQRDPLAELTRLFAGVKA-------KQNRGDS-LPIEER
LKLHIIDGERIGLEAQLAKALEQ-YPPLDIINTFLLDGMKVVGELFGAGQMQLPFVLQSAETMKAAVAYLEPFMEKSGASNGKGIFVIATVKGDVHDIGK
NLVDIILSNNGYKVINLGIKQPVENIIQAYEKHQPDCIAMSGLLVKSTAFMKENLEVFNEKGITVPVILGGAALTPKFVNQHGKVIYGKDAFDDLNFMDK
LM-
>tr|Q8DK43|Q8DK43_THEEB 5-methyltetrahydrofolate--homocysteine methyltransferase OX=197221 OS=Thermosynechococcus elongatus (strain BP-1). GN= PE=3 SV=1
---YLHAEPR-RVIVFDGAMGTNLQAQNLTAGGCNEYLVISQPEPVAKVHRDFLAAGADVIETNTFGSSSIVLSENLRAYEISKTAAELAKSVAAEPRFV
AGSMGPGTKLPT-LGHIDYDTLYRAFREQAAGLFDGGVDLFIIETCQDVLQIKAALNGVMAVERRPLMVSVTMEQGTMLVGSEIGAALTILEPYPIDILG
LNCATGPDLMTEHIRYLAQHSPFVISCIPNAGLPEN-IGGHAHYKLTPMELRLALTRFVDFGVQVIGGCCGTRPDHIAALAEIAATLTPKARSP--QRIP
AAASIYSPQPYDQENSFLIIGERLNASGSKKCRDLLNAEDWDGLVALARAQVREGAHILDVNVDYVGRDGVRDMRELVSRLVTNVTLPLMLDSTEWQKME
AGLKVAGGKCLLNSTNFEEPRFYKVLELAKTYGAGVVIGTIDEEGMARTAEKKFAIAQRAYRAALDYGIPPWEIFFDPLALPISTGIEEGRETIEAIRRI
RAELGCHILLGVSNISFGLNARQVLNSMFLHEAIQAGMDAAIVSAAKILPLAKIECRDLIYDRRDPLAELTRLFEGKSA-------KQNRSVN-LPIEER
LKRHIIDGDRLGLEDTLAQALET-YAPLEIINTFLLDGMKVVGELFASGQMQLPFVLQSAETMKAAVAYLEPFMEKSATDTAKGTVVIATVKGDVHDIGK
NLVDIILTNNGYRVINLGIKQPVENIIQAYEEHQADCIAMSGLLVKSTAFMKENLEVFNERGITVPVILGGAALTPKFVYEHGQVIYGKDAFADLHFMDR
LM-
>tr|D1BG25|D1BG25_SANKS Methionine synthase (B12-dependent) OX=446469 OS=ST-74). GN= PE=3 SV=1
---LKSAIAT-RVVVADGAMGTMLQAADLSLGGCNEILNVTRPDVVESVHDAYFAVGVDCVETNTFGANWSNLGDGIRIFELAEAGARVARRSADKPRWV
LGSMGPGTKLPS-LGHTSYAHLRDTFAQQAAGLVAGGADAILVETSQDLLQTKAAVNGSKKAVEVPIFVQVTVETGTMLMGSEIGAALTTLAALGIDSIG
LNCATGPAEMSEHLRHLAKHSAVPVTCMPNAGLPVL-GANGAHYPLSPAELAVAHQQFVEFGLGLVGGCCGTTPEHLRAVVDAVGGAPVVERTP--EPEK
GVASLYTHVDFDQDASFLAIGERTNANGSKAFREAMLAEDWDECVQIARAQTRDGAHLLDVCVDYVGRDGVADVRSVVSRLASASTLPLVIDSTEPPVIQ
AGLELVGGRGVVNSVNFEDSRYGRIMPLVKEHGAAVIALTIDEEGQARTAKTKLAIASRLVDDLTRWGMDVADIIVDTLTFPIATGQEEAIETIEAIRAL
KAKYGVHTTLGVSNVSFGLNARVVLNSVFLHEAVQAGLDSAIVHAAKILPLAKIPALDLVWDRRDPLARLLDLFAGVDTAA----LKDQRAEAALPLGER
LERRILDGDLKGLDTDLDLALGEG-TALAIINDHLLEGMKVVGELFGKGEMQLPFVLQSAEAMKTAVAYLEPHMEKTD-EAGKGTIVLATVRGDVHDIGK
NLVDIILTNNGYTVVNIGIKQTIAAMIEAAEEHHADVIGMSGLLVKSTVVMRENLEELNARGLKYPVLLGGAALTRTYVEDDGQVRYARDAFEGLRLMEP
LV-
>tr|C1DU66|C1DU66_SULAA Methionine synthase OX=204536 OS=Sulfurihydrogenibium azorense (strain Az-Fu1 / DSM 15241 / OCM 825). GN= PE=3 SV=1
---LRSLIKE-RVLVIDGAMGTMIQSTIIPMGGCNEILNITAPQIIQNIHEKYLQAGADIIKTNTFGALPWVLEEGIKAYELAKAGALLVKQLCDKPRFV
AGSLGPGTKLPS-LGHIDYDTMYEGYKVAAYGLIDGGVDVFLVETCQDPLQIKVALHALNDAKDIPIMVSATIETGTMLIGTDAQTLAAIMEPFDILTLG
FNCGTGPDQVEQHLRKLSQVWKGYISVHANAGLPEN-RGGQTYYPMNAEEFAEKESKFLIDGVAIVGGCCGTTPSHIKALYEKVKGKKPKKPVG--KQ-P
KLASLFMTQPLKQDPPPFLVGERTNATGSKQFRELLLKEDYDGILAIAQDQVKSGSHALDVSVNYAGRDEIKDMKEVIRRFNEKIPIPLMVDSTQPKAIE
AGLKHIGGKPIINSANLEEEKFDKICQLAKRFGTSLVLLAIDEQGMAKTKERKLEVAERMYERATVHGLDPEDLVFDLLTFTVGSGDQEAVQTIEAIREL
RKRHEVGAVLGISNVSFGLDARKYLNSVFLHHCVEAGLTMAIVNPKHLIPFHKISCENLLFNVWDPLFEFIHYFSKKKESI----LSEESKK--LPIEEK
IKKLLIDGEKEKLIKAVEEARHK-IPPEKIINEILIDAMKIVGDLFGEGKMQLPFVLQSAESMKAAVDYLNQFLPKTT-KKKKTTLVLGTVKGDVHDVGK
NLVDIILTNNGFNVVNLGIKVELEQFLKAAEEHKADAIGMSGLLVKSTLEMKNNLEEMQKRGIKIPVLLGGAALNKKFVDEDGPIFYCRDAFDGIEAMTR
IF-
>tr|K9V3R3|K9V3R3_9CYAN Methionine synthase (B12-dependent) OX=1170562 OS=Calothrix sp. PCC 6303. GN=Cal6303_3820 PE=4 SV=1
---RLHSPER-PVIVFDGGMGTHLQTQNLTPGGCNEYLVHTKPEAVEKVHRDYLAAGADVIETDTFGGTPIVLAENLQTYYLNKTAAELAKRVAAEPRFV
AGSMGPTTKLPT-LGHIDYDTLKDDFVQQAEALWDGGVDLFIIETCQDVLQIKAALNAVEEVKRIPLMVSVTMEMGTMLVGTEINAVVTILEPYKIDILG
LNCATGPDLMKPHIKYLSEHSPFVVSCVPNAGLPEN-VGGKAHYRLTPMELRMSLMHFVDLGVQVIGGCCGTRPEHIQQLAEITKELKPKLRTP--RLEP
AAASIYSTQNYTQDNSFLIVGERLNASGSKKCRDMLNAEDWDGLVSMARAQVKEGAHILDINVDYVGRDGVRDMRELVSRIVNNVTLPLMLDSTEWEKME
AGLKVAGGKCILNSTNFEEERFFKVLELAKRYGAGVVIGTIDEEGMARTAEKKFQIAQRAYRAALEYGIPAHEIFFDTLALPVSTGIEEGKATIEAIRRI
RQELGCHFMLGVSNISFGLNSRIVLNSMFLNEAMSAGMDGAIVSPNKILPLSKIECRDLIYDSRDPLGELTTLFEGVTT-------KRDKGDS-LPVEER
LKRHVIDGERIGLEDALKQAMEK-YPPLDIINIYLLDGMKVVGELFGSGQMQLPFVLQSAETMKSAVAFLEPHMEKNESDNSKGRFIIATVKGDVHDIGK
NLVDIILSNNGYKVINLGIKQPVENIIEAYEKHKPDCIAMSGLLVKSTAFMKENLETFNEKGISVPVILGGAALTPKFVYEKGKVVYGKDAFSDLNFMDK
LM-
>tr|K7RX62|K7RX62_PROA4 Methionine synthase (5-methyltetrahydrofolate:L-homocysteine S-methyltransferase) OX=1171373 OS=6432 / NBRC 12425 / NCIMB 8070). GN= PE=4 SV=1
---LRALLGS-RLLIIDGAMGTMLQNVDLTMGGCNEILNVTRPDVVSGIHEAYLEAGADLIETNTFGVNLAALGEDIRITELAAAGTRLARTAADQPRFV
LGSLGPGTKLPT-LGQIGFADIRDAYQLAVEAMIDEGVDAVQLETCQDLLQAKAAVIAAHRAVDLPVLVDITVETGTMLMGSETGAALTVLESLGIDAIG
MNCATGPAEMAEHLRTLSRGASVPVMCMPNAGLPEI-TGQGARYPLGPADITGALSDYARFGLSVVGGCCGTTPEHIAVLADALAGRPVAGREV--HHVD
AVASLYNEVPLSQDTAYLSIGERTNANGSKAFREAMLAENWDECLDIAKAQTRDGAHLLDLCVDYVGRDGAADMAELSSRMATAVTLPIVLDSTEPQVLR
TGLEHLAGRCIINSVNYEDSRFARVMPLVREHGAGVVALTIDEEGQARTREWKVRVASRLIDDLTNWGMDVGDILVDCLTFPIATGQEEGIETIEAIREL
KKRYGVRTTLGVSNISFGLNARIVLNSVFLHEAVAAGLDSAIVHAAKIVPIDRIPALDLVHDRRDPLTRFLELFEGVTAAS----MKAEREEAAMPLLER
LKQRIIDGNAKGLTEDLDEALRQK-PALDIVNEDLLAGMQVVGDLFGSGRMQLPFVLQSAEVMKTAVAHLEPHMEKTD-AAGKGTLVLATVKGDVHDIGK
NLVDIIVSNNGYSVVNLGIKQPVQAIIEAAEGHHADAIGMSGLLVKSTMVMRDNLLELNDKGLRYPVMLGGAALTRSFVEHEGDVRYAKDAFEGLRLMDA
VM-
>tr|K9SW62|K9SW62_9SYNE Methionine synthase (B12-dependent) OX=1173263 OS=Synechococcus sp. PCC 7502. GN=Syn7502_01998 PE=4 SV=1
---RLHSSDR-PVIVLDGAMGTNLQLQNLTAGGCNEYLVITKPEAVAKVHRDFLAAGADVIETDTFGGTSIVLGEDLRAYELSKKAAELAKSLTQEPRFV
AGSIGPTTKLPT-LLHIDFDTMKQSFIEQVEGLIDGGVDLLLVETCQDILQIKVTLNAIEEVIRLPLMVSVTMEQGTMLVGTEINAVTTILEPYNIDILG
LNCATGPDKMTDHIKYLSEHSKFVVSCVPNAGLPEN-VGGKAFYKLTPEDLKAHLSYFVDLGVQVIGGCCGTRPEHIQALAELANELKPKVRSP--QITP
SAASIYSSQPYTQDNSFLIIGERLNASGSKKCRDLLNAEDWDGLVALGRSQVKEGAHILDVNVDYVGRDGVRDMHELVSRLVTNVTIPLMLDSTEWEKME
AGLKLAGGKCLLNSTNYEEPRFCKVLELAKTYGAGVIIGTIDEEGMARTADKKFTIAQRAYKQATEYGLAPQEIFFDTLALPISTGIAEAAETIEANRRI
KAAMDCHIILGVSNISFGLNSRIVLNSVFLHEAQKAGMDSAIVNASKILPLNRIDARQLVYDERDPLGEFTKLFEGVTT-------KRDKSDN-LPIEEK
LKRHIIDGERLGLEQNLAIALNT-YAPLDIINNLLLDGMKVVGELFGSGQMQLPFVLQSAETMKSAVAYLEQFMDKVE-GSNKGVFLIATVKGDVHDIGK
NLVDIILSNNGYKVVNIGIKQSVENIIQAYEEHKADCIAMSGLLVKSTAFMKENLTEFNKRGISVPVILGGAALTPKFVHENGKVVYGRDAFSDLNFMDA
YM-
>tr|K1VV61|K1VV61_9ACTO Methionine synthase (B12-dependent) OX=1195457 OS=Streptomyces sp. SM8. GN= PE=3 SV=1
---LREALAT-RVVVADGAMGTMLQAQDPTLQGCNEILNLTRPDIVTSVHDAYFAVGVDCVETNTFGANHAALGEDIRVFELSEAGARVARESADRQRWV
LGSMGPGTKLPT-LGHAPYTTLRDAYQRNAEGMIAGGADALLVETTQDLLQTKASVIGARRAANLPVIVSVTVETGTMLLGSEIGAALTALEPLGIDMIG
LNCATGPAEMSEHLRHLARHSRVPISCMPNAGLPVL-GKDGAHYPLTASELADAQEGFVEYGLSLVGGCCGTTPEHLRQVVERVRGAVPGERDP--RPEP
GAASLYQTVPFRQDTSYLAIGERTNANGSKKFRTAMLEGRWDDCVEMAREQIREGAHLLDLCVDYVGRDGVADMTELAGRFATASTLPLVLDSTEVDVLR
AGLEKLGGRAVINSVNYEDSRFAKVTALAQEHGAALMALTIDEEGQARTTEHKVAVAERLIEDLTNWGIHESDILIDTLTFTICTGQEEGVHTIEAIREL
KRRHDVQTTLGLSNISFGLNARIVLNSVFLDECVKAGLDSAIVHASKILPIARLEALDLIHDRRDPLQTFLELFEGVDTKS----MKAGKAELALPLDER
LKRRIIDGEKNGLHEDLDEALTER-PALDIVNDTLLDGMKVVGELFGSGQMQLPFVLQSAEVMKDAVAHLEPHMEKAE-GDGKGTIVLATVRGDVHDIGK
NLVDIILSNNGYNVVNLGIKQPVSAILEAAEEHRADVIGMSGLLVKSTVIMKENLEELNQRGLGYPVILGGAALTRAYVEQEGEVRYARDAFEGLRLMDA
LI-
>tr|D3Q595|D3Q595_STANL Methionine synthase OX=446470 OS=102104 / LLR-40K-21). GN= PE=3 SV=1
---FLSALKH-RILVADGAMGTMLQDAQLEIGGCNEILNVSRPDVVRDIHDAYFAAGADMVETNSFGSNMTNLGEDIRIRELSQRSAELAKEVASGPRFV
LGSIGPGTKLPT-LGHAPYAVLRDAYLENAAGLILGGADALIVETSQDLLQTKAAIVGAQRAIQVPIIASVAVETGTMLVGSEIGAALTALAALKVDLIG
LNCSTGPAEMSEHLRYLSQYSRIPLSVMPNAGLPEL-GPNGAIFPMTPPKFTEAIDEFAEFGVALVGGCCGTTPEHIRQVYERVGQREPVRRTI--ADEP
GVSSVYHHVPFKQDASILNVGERTNANGSKAFREAMLAADWDKCVDIARDQARAGSHLLDLCVDYVGRDGRDDMRELAGRFATASTLPIMLDSTEPGVIE
AGLESLGGRCIVNSVNFEDSRYAKAMPAIVEHGAAVVVMCIDEEGQARTADRKIEIAARTIDDLVNWGMRVSDIFVDALTFPISTGQEEGIETIDAIRGI
AERYGINFTLGISNVSFGLNSRQVLNSVFLHECVEAGLTSAIVHASKILPMSKIEALDMVYDRRDPLQRFIELFEGVDMAS----ARASRAEAALPLNER
LERRVIDGERNGLEADLDAALVER-SALDIVNDTLLNGMKTVGELFGSGQMQLPFVLQSAEVMKTAVAYLEPHMEKAD-SEGKGTIVLATVKGDVHDIGK
NLVDIILSNNGYSVVNIGIKQPINAIVDAAEQHNADAIGMSGLLVKSTVIMKENLAEMMSRGVRWPVLLGGAALTRSYVEDAGEVHYAKDAFEGLSLMER
VM-
>tr|B5I559|B5I559_9ACTO Methionine synthase OX=463191 OS=Streptomyces sviceus ATCC 29083. GN=SSEG_06906 PE=3 SV=1
---LREALAT-RVVVADGAMGTMLQAQDPTLNGCNEILNVTRPDIVRSVHDAYFAVGVDCVETNTFGSNHTAASEDIRVHELSEAGARIAREAADDPRWV
LGSVGPGTKLPT-LGHIDYATIRDGYQANVEGLLAGGADALIVETTQDLLQTKASVLGARRAADVPLVVSMAFETGTMLLGSEIGAALTALEPLGIDMIG
LNCSTGPAEMSEHLRYLARHSRIPLLCMPNAGLPIL-TKDGAHFPLDPEGLADAQENFVDYGLSLIGGCCGTTPEHLRQVVERVRELTPAERNP--QPEP
GAASLYQTVPFRQDTSYLAIGERTNANGSKKFREAMLEARWDDCVEMAREQIREGAHMLDLCVDYVGRDGVADMKELAGRFATASTLPIVLDSTEVPVIQ
AGLEKLGGRAVINSVNYEDSRFAKVTKLAQEHGAALIALTIDEEGQARTPEKKVEIAERLIDDLTNWGIHESDILIDTLTFTICTGQEEGVATIEAIREL
KRRHDVQTTLGLSNISFGLNARVLLNSVFLDECTKAGLDSAIVHASKILPIARFTALDLIYDRRDPLQKLMALFEGATTKS----LKAGRAEAALPLDER
LKRRIIDGEKNGLEADLDEALTDR-PALDIVNDTLLDGMKVVGELFGSGQMQLPFVLQSAEVMKTAVAYLEPHMEKGD-EAGKGTIVLATVRGDVHDIGK
NLVDIILSNNGYNVVNLGIKQPVSAILDAAAEHRADVIGMSGLLVKSTVIMKENLEELNQRGLDFPVILGGAALTRAYVEQEGEVRYARDAFEGLRLMDA
LI-
>tr|E8N466|E8N466_ANATU Methionine synthase OX=926569 OS=UNI-1). GN= PE=3 SV=1
---YLDLIQK-RVAIFDGAMGTSLQKQNLTAGGCNDYLVLTYPQAVETVHRSFLEAGVDVLETDTFRSNRITLAEGLRVLDINRAAANLARRLADEMRLV
AGSIGPSGKLPSMLSNITFDELADVFREQARGLMEGGVDLLLIETSQDILEVKAAITGIQQAIVIPLQAQVTLDTGRMLLGTDIAAVLAILEGMPIDAIG
LNCSTGPDYMREPIRYLAEHAPVPVSCIPNAGLPLN-VDGQAVYPLEPEPFATALSEYVRFGVGIVGGCCGTTPEHLRKLVEKI-DAHASHRPI--FS-P
KLASATQAVLMVQEPAPFLIGERLNTQGSARFKKMILAEDFEGALEIARQQVEAGAHGLDLCTALTERDEGELMRRLIKTLAPTVRVPFVIDTTEPDVME
IALKTAPGRCLLNSVNLEAAKATRILQLAKMYNAAVIALTIDEQGMAKTAQRKLEIARRIYHLAVEMGLRPQDLVFDALTFTLATGDPEAMETMDGIRLI
KAELGVLTSLGVSNVSFGLKARGVLNSVMLYHCVQAGLDMAIVNPAQITPYPDIPAEDLIFNRRDALQRLIEYFEGKEEQK----TTAQHSAG-KTAEER
LHWRIVHRQKEGVEADIDEILRHE-TAVRVLNEVLLPAMKEVGDRFGAGELILPFVLQSAEVMKKAVSHLEQYLEKKE---GKGTLVLATVYGDVHDIGK
NLVKTILSNNGYTVIDLGKQVPAETIITKAVEVKADAIGLSALLVSTSKQMPLIVNELHRRGLKFPVLIGGAAINRNFTEDDPGVFYCKDAFEGLSTMDA
LM-
>tr|F3Z6H0|F3Z6H0_9ACTO Putative 5-methyltetrahydrofolate:homocysteine S-methyltransferase OX=355249 OS=Streptomyces sp. Tu6071. GN=STTU_5698 PE=3 SV=1
---LREALAS-RVVVADGAMGTMLQAQNPTLDGCNEVLNVTRPDIVRSVHEAYFDVGVDCVETNTFGANHSAFGEEIRIHELSEAGARLARETADSTRWV
LGSIGPGTKLPT-LGHLPYGVLRDGFQQNAEGLLAGGADALIVETTQDLLQTKASVLGARRAADVPLIVSLAFETGTMLLGSEIGAALTALEPLGIDLIG
LNCSTGPAEMSEHLRYLAQHSRIPLTCMPNAGLPVL-TKDGAHFPLTAPEMADWQESFVDYRLSLVGGCCGSTPEHLRQVVERVRGMAPGTREP--QPEP
GAASLYQTVPFRQDTSYLAIGERTNANGSKKFREAMLEARWDDCVEMAREQIREGAHMLDLCVDYVGRDGVADMRELAGRFATASTLPLVLDSTEVDVLE
AGLEMLGGRAVINSVNYEDSRFAQVTSLAREHGAALIALTIDEEGQARTVETKVAVAERLIADLTNWGIHESDILVDCLTFTICTGQEEGIATIEAIREL
KRRHDVQTTLGLSNISFGLNARILLNSVFLDECVKAGLDSAIVHASKILPIARFSALDLVHDRRDPLQKLMRLFEGATAKS----LKAGKAEAALPLDER
LKRRIIDGERNGLEADLDEALQTR-PALDIVNATLLDGMKVVGELFGSGQMQLPFVLQSAEVMKTAVAHLEPHMEKSD-AEGKGTIVLATVRGDVHDIGK
NLVDIILSNNGYNVVNLGIKQPVSAILEAAEEHRADVIGMSGLLVKSTVIMKENLQELNQRGMDYPVILGGAALTRAYVEQEGEVRYARDAFEGLRLMDA
LI-
>tr|G0Q6E8|G0Q6E8_STRGR Methionine synthase OX=649189 OS=Streptomyces griseus XylebKG-1. GN=SACT1_6180 PE=3 SV=1
---LREALAT-RVVVADGAMGTMLQAQDPTLNGCNEILNITRPDIVRSVHEEYFAVGVDCVETNTFGANHSAANEEIRIFELSESGARIAREVADEQRWV
LGSIGPGTKLPS-LGHIAYDVLRDGYQKNAEGLLTGGSDALIVETTQDLLQTKSSIIGARRAVHVPLICSLAFETGVMLLGSEIGAALTALEPLGIDLIG
LNCSTGPDEMSEHLRYLARHSRTPLMCMPNAGLPVL-TKDGAHFPLGPDGLADSQENFVDYGLSLIGGCCGTTPEHLRAVVDRARELTPTERDP--RPEP
GAASLYQTIPFRQDTAYLAIGERTNANGSKKFREAMLEARWDDCVEMARDQIREGAHMLDLCVDYVGRDGVADMAELAGRFATASTLPIVLDSTELPVLR
AGLEKLGGRAVLNSVNYEDSRFAQVSALAAEHGAALIALTIDEEGQARTVENKVAIAERLIEDLTNWSIRESDILIDTLTFTICTGQEEGIATIGAIREL
KKRHDVQTTLGLSNISFGLNARVVLNSVFLDECVKAGLDSAIVHASKILPIARLEALDLIYDRRDPLQKLMELFEGVNMKS----MKAGKAEMALPLDER
LQRRIIDGEKNGLEADLDEALQDT-PALDIVNNTLLEGMKVVGELFGSGQMQLPFVLQSAEVMKSAVAHLEPHMEKSD-DEGKGTIVLATVRGDVHDIGK
NLVDIILSNNGYNVVNLGIKQPVSAILEAAEEHRADVIGMSGLLVKSTVIMKENLQELNQRKMDFPVILGGAALTRAYVEQEGEVRYARDAFEGLRLMDA
LI-
>tr|D9XT49|D9XT49_9ACTO Methionine synthase OX=467200 OS=Streptomyces griseoflavus Tu4000. GN=SSRG_05052 PE=3 SV=1
---LREALAS-RVVVADGAMGTMLQAHDPTLNGCNEILNLTRPDIVRSVHAEYFDAGVDCVETNTFGANLTALGEDIRVVELSEAGARIARETADEARWV
LGSMGPGTKLPT-LGHTTFGAIRDAYRQNAEGLLAGGADALLVETTQDLLQTKASVVAARRAFEVPLIVSVTVETGTMLLGSEIGAALTALEPLGIDMIG
LNCATGPAEMSEHLRHLARHSRVQLSCMPNAGLPEL-TKDGARYPLSPGELADAQENFVDYGLSLVGGCCGTTPEHLRQLVERVRGLAPVERDP--RPEP
GAASLYQSVPFRQDTAYLAIGERTNANGSKKFREAMLEGRWDNCVELAREQIREGAHMLDLCVDYVGRDGVADMEELAGRFATASTLPIVLDSTEVDVIR
AGLEKLGGRAVINSVNYEDSRFARVTRLAQEHGAALIALTIDEEGQARTAEKKVEIAERLIDDLTNWGIREEDILVDCLTFTICTGQEEGVATIEGIREL
KRRHKVQTTLGLSNISFGLNARILLNSVFLDECVKAGLDSAIVHASKILPIARFSALDLIHDRRDPLQKLMALFEGATAKS----LKAGKAEAALPLEER
LKRRIIDGERNGLEADLDEALQTR-KALAIVNDTLLDGMKVVGELFGSGQMQLPFVLQSAEVMKTAVAHLEPHMEKTD-EAGKGTIVLATVRGDVHDIGK
NLVDIILSNNGYNVVNLGIKQPVSAILEAADEHRADVIGMSGLLVKSTVIMKENLEELNQRGLDYPVILGGAALTRAYVEQQGEVRYARDAFEGLRLMDA
LI-
>tr|B4VAC2|B4VAC2_9ACTO Methionine synthase OX=465541 OS=Streptomyces sp. Mg1. GN=SSAG_04700 PE=3 SV=1
---LREALAT-RVVVADGAMGTMLQAQDPTLNGCNEVLNVTRPDIVRSVHEEYFSVGVDCVETNTFGANFAALAEDIRNFELSESGARIAREVADEQRWV
LGSMGPGTKLPT-LGHIEYATIRDAYQTNAEGLISGGADALLVETTQDLLQTKSSIIGARRAVRVPLICSVTVETGTMLLGSEIGAALTSLEPLGIDMIG
LNCATGPAEMSEHLRYLARNSRIPLSCMPNAGLPVL-GKNGAHYPLSASELADAQETFVEYGLSLVGGCCGTTPEHLRQVVERVRDLSPVTRVP--QPEP
GASSLYQTVPFRQDTSYMAIGERTNANGSKKFREAMLEARWDDCVEMARDQIREGAHMLDLCVDYVGRDGVADMRELAGRFATASTLPIVLDSTEVPVIQ
AGLEKLGGRAVINSVNYEDSRFAKVTRLAQEHGAALIALTIDEEGQARSAEHKVAIAERLIDDLTNWGIHESDILIDTLTFTICTGQEEGIATIEAIREL
KRRHDVQTTLGLSNISFGLNARVLLNSVFLDECVKAGLDSAIVHASKILPIARFDALDLIYDRRDPLQKLMALFEGVNTKS----LKAGRAELALPLDER
LQRRIIDGEKNGLEADLDEALQTR-PALDIVNDTLLEGMKVVGELFGSGQMQLPFVLQSAEVMKTAVAYLEPHMEKTD-DEGKGTIVLATVRGDVHDIGK
NLVDIILTNNGYNVVNIGIKQPVSAILEAAEEHKADVIGMSGLLVKSTVIMKENLEELNQRKLDYPVILGGAALTRAYVEQEGEVRYARDAFEGLRLMDA
LI-
>tr|C7Q855|C7Q855_CATAD Methionine synthase OX=479433 OS=102108 / JCM 14897). GN= PE=3 SV=1
---LREALRT-RVVVADGAMGTMLQAQNPTLGGCNEILNISRPDIVQTVHEEYFRAGVDCVETNTFGANHTNLGDDIRVFELSEAGARLAREVADGPRWV
IGSIGPGTKLPS-LGQIGYATLRDAYQAEAAGLIAGGADALLVETSQDLLQIKASVLGAKAAIDVPVWASAAFETGTMLLGTEVGAALTALESLGIERIG
LNCSTGPAEMSEHLRYLAKHSTIGLSCMPNAGLPVL-TSDGAHYPLSPEELVDWHARFVQFGIALIGGCCGTTPEHLRQLVESLGGREVPQRDP--KREP
GASSLYQHVPFRQDISYLAIGERANTNGSKAFREALLAENWDACVEIARNQIRDGAHMLDLCVDYVGRDGVRDMQQVASRFATASTLPIVLDSTEPQVLQ
AGLETLGGRAVINSVNYEDSRFARIMELVSAHGAGVIALTIDEQGQARTAEHKVAIAERLIEDITNWGVPEDSILVDCLTFTICTGQEEGLETIEGIREL
KRRHDVQTTLGLSNISFGLNARQVLNSVFLHECVEAGLDSAIVHASKILPIARIPALDLVYDRRDPLTRLLELFEGVDAAS----LKASRAEAALPLNER
LKRRIIDGERKGLEADLDEALGER-PALEIVNEVLLDGMKTVGELFGSGEMQLPFVLQSAETMKTAVAHLEPHMEKSD-STGKGTIVLATVKGDVHDIGK
NLVDIILSNNGYNVVNLGIKQPLQTILDAAEEHAADAIGMSGLLVKSTVVMKENLEEMNTRGVRWPVLLGGAALTRAYVEQDGEVRYARDAFEGLNLMDA
VA-
>tr|C7NB07|C7NB07_LEPBD Methionine synthase OX=523794 OS=10249). GN= PE=3 SV=1
---LQNDLKN-KILLLDGAMGTMIQQENLTAGGCNDYLVLQRPDVIKNIHKKYLEAGSDIIETNSFGALDIVLKDDLTVFEMNKKAAELVNEAIAENLYV
AGALGPSNKSISVTGGVTFEELIHTYYTAVSGLMAGGVDLILFETIQDTRNLKAAYLGLKKAYTVPLMLSFTIETGTTLAGQTADAFYYAVNHMNPFSVG
LNCATGPEFMTQFLKTLNNISNTYISVYPNAGLPNE----DGEYEETPDTLSAKIEPFFNNYLNIVGGCCGTTPEHIQKIKEKSIN--YSPRID----EN
KDFNDVSGLITLEKDRPIYVGERTNVIGSRIFKNLIASEKFDEATEVARLQIKGRADVIDICLANPDRDEIADMKAFLDKVAKFAKVPLMIDSTDINVVK
EGLTYLQGKGIINSINLEEKKFTDMAKVIKDFGASVVVGLIDEEGMAVSVERKLEIARRSYELLTKYGIDERDIIFDTLVFPVATGDQKATATIEAIRQI
KDEMNVKTILGVSNISFGLPGREVLNTYYMQKAYEAGLDYAIVNTEKVIPMSEISSENILF---ENVSKFANFYREKKAIQ-------KVVTSNMTMEER
VANLVVEGSKKDLKICLDELLKK-YSPIEIINGPLMDGMDEVGRLFNNNDLIVAEVLQSAEVMKASVSHLEQFMEKDE-SSVKGTVIMATVKGDVHDIGK
NLVGIIIGNNGYKVIDLGINTPAEKIREAIIEHKADFLGLSGLLVKSATEMVNTMEVLHEAGIDIPIFVGGAALTEKFTVNKNIVIYSRDAMTALADLNK
MI-
>tr|L1MH83|L1MH83_9CORY 5-methyltetrahydrofolate--homocysteine methyltransferase OX=1035195 OS=Corynebacterium durum F0235. GN=HMPREF9997_01139 PE=4 SV=1
---FLDALSS-RVLIGDGAMGTQLQSFDLDVGGCNEILNDTRPDVLRQIHRAYFDAGADVVETNTFGCNLPNLADGIRCRELALKGTALAREVADEEKFV
LGSMGPGTKLPS-LGHAHYEDLKRYYKEAALGMIEGGADGILIETAQDLLQVKAAVLGCHEAITLPIVCHVTVETGTMLLGSEIGAALTALEPLGINMIG
LNCATGPHEMSEHLRYLSQHASIPVSVMPNAGLPIL-GKNGAEYPLTPSELGAALRTFVDYGLALVGGCCGTTPEHIRAVRDAVVD--QAQRTP--AMED
NVSSLYATMPLTQDTGITMIGERTNANGSKAFREAMLAGDWETCVDIAKQQTRDGAHMLDLCVDYVGRDGRADMAQLAGLLSTSSTLPIMIDSTEPAVIQ
TGLEHLGGRCAVNSVNFEDSRYQRIMRLVKQHGAAVVALTIDEEGQARTADKKVEIATRLIEDITTWGLDHNDIIVDCLTFPISTGQEEGIETINAIRML
KEKYRVHTTLGLSNISFGLNARQVLNSVFLNECIEAGLDTAIAHSSKILPMNRIHALDMVYDRRDPLQKFMELFEGVSAAD----AKDARAAAAMPLFER
LAQRIIDGEKNGIEVDLDAGMAEK-SPIEIINQDLLGGMKTVGELFGSGQMQLPFVLQSAETMKTAVAYLENFME-------KGKIVLATVKGDVHDIGK
NLVDIILSNNGYEVVNLGIKQPISTIISAVRDHNADVVGMSGLLVKSTVIMKENLEEMNTAG-DIPVLLGGAALTRTYVENQGDVHYARDAFEGLRLMDD
IM-
>tr|B5H8L9|B5H8L9_STRPR 5-methyltetrahydrofolate:homocysteine S-methyltransferase OX=457429 OS=Streptomyces pristinaespiralis ATCC 25486. GN=SSDG_01499 PE=3 SV=1
---LREALAT-RVVVADGAMGTMLQAQDPTLNGCNEVLNVTRPDIVRSVHEAYFEVGVDCVETNTFGANHSAMGEDIRVYELSESGARIAREVADEQRWV
LGSIGPGTKLPT-LGHAPYTVLRDGFQQNAEGLIAGGADALIVETTQDLLQTKAAILGARRAADLPLLCSLAFETGTMLLGSEIGAALTALEPLGVDMIG
LNCSTGPEEMSEHLRYLTRHSRIPLLCMPNAGLPVL-TKDGAHFPLGPEGLAEAQEQFVDYGLSLVGGCCGTTPEHLRQLVERVRGAELTPRDP--RPEP
GAASLYQTVPFRQDTAYMAIGERTNANGSKKFREAMLEGRWDDCVEMARDQIREGAHMLDLCVDYVGRDGVADMEELAGRFATASTLPIVLDSTEVDVIE
AGLEKLGGRAVINSVNYEDSRFAKVTALAKEHGAALIALTIDEEGQARSVEHKVAVAERLIEDLTNWGIHESDILIDTLTFTICTGQEEGLNTIEAIREL
KRRHDVQTTLGLSNISFGLNARILLNSVFLDECVKAGLDSAIVHASKILPIARFDALDLIYDRRDPLQKLMALFEGATTKS----LKAGKAEAALPLEER
LKRRIIDGEKNGLEADLDEALRER-AALDIVNDTLLDGMKVVGELFGSGQMQLPFVLQSAEVMKNAVAHLEPHMEKTD-ADGKGTIVLATVRGDVHDIGK
NLVDIILSNNGYNVVNLGIKQPVSAILDAAKEHKADVIGMSGLLVKSTVIMKENLQELNQRGMDYPVILGGAALTRAYVEQEGEVRYARDAFEGLRLMDA
LI-
>tr|E1IGB4|E1IGB4_9CHLR Methionine synthase OX=765420 OS=Oscillochloris trichoides DG-6. GN=OSCT_2365 PE=3 SV=1
---YLQALAE-RVLIFDGAMGTSIDTFNLTVGGNRDYLVMTRPDVIGQIHASYLEAGADVIETCTFQSTRLRLEEGLRTVELNQAAATLARSVADRPRFV
AGSMGPTGKLPSSLSDITFQQLSDIYREQATGLIQGGVDLLLVETSVDVLEVKAALDGIRRARDVAVQAQVFLDSGRMLLGTDVPALIATLEAMPVDVIG
LNCSTGPEHMREAIQYLTAHSRKPISCIPNAGLPLE-VDGETVYPMQPDEFSRILGEFVDYGVAVVGGCCGTRPSHIAAVRETL-GLNPKQREV--DY-P
SVSSGIRAAALRQEGTLTLIGERVNTLGSRKVKRLLLSDNYDGVVEVAREQVDNGAHLLDVCVAMTERDESVQMNALLKKLTMNIELPLVIDTTETDVLE
QALAMYPGRAVVNSLSLERGKIDKVLPLVARYGAATMAMTIDEEGMCHTRERKLAVAERIAQIAREYGVPAEALIFDVLTFPITTGQEEAVETIEGIRLV
KERIGCFTTLGVSNLSFGVAARAALNSVFLFHAMAAGLDTAIINPAHITPYTEIPCEDLIFNRRDALARFIGYFEQASPEQ----EGADPTAG-LSVDER
LHWKILHRKKEGVEADIEEAVRGV-AAVEVLNNVLLPAMKQVGDLFGAGQLILPFVLQSAEVMKKAVARLEHYLEKME---GKGKVLLATVLGDVHDIGK
NLVNTILANNGYTVYDLGKQVPVNTIIEQAIELQVDAIGLSALLVSTSKQMPLVVQELHQRGMNLPVLVGGAAINKQFVAEAGGVFYCKDAFEGLEAMDR
LS-
>tr|F8K2K8|F8K2K8_STREN Methionine synthase OX=1003195 OS=14057 / NRRL 8057). GN= PE=3 SV=1
---LREALAT-RVVVADGAMGTMLQAQDPTLGGCNEVLNVTRPDIVRSVHEEYFQAGVDCVETNTFGANLAALGEGIRIHELAEAGARLAREVADSPRWV
LGSVGPGTKLPT-LGHAPYTALRDAYRTEVAGLVAGGADAILVETTQDLLQTKAALIGARQALDLPLICSVTVETGTMLLGSEIGAALTALEPLGIDMIG
LNCATGPAEMSEHLRYLARHARIGVSAMPNAGLPVL-GKDGAHYPLSPAELADAQELFVEYGLTLVGGCCGTTPEHLRQVVQRVRGREVAPRDP--RPEP
GAASLYQSVPFRQDTSYLAIGERTNANGSKKFRTAMLEGRWDDCVEMAREQIREGAHLLDLCVDYVGRDGAADMREIAGRLATASTLPIVLDSTEPAVLQ
AGLELLGGRAVVNSVNYEDSRFARITSLAVEHGAALMALTIDEEGQARTVERKVAVAERLIADLTNWGIRECDIIIDCLTFTICTGQEEGANTIEAIREL
KRRHEVQTTLGLSNISFGLNARMVLNSVFLHECVAAGLDSAIVHAAKIVPIARIPALDLIHDRRDPLQRFLEIFEGVDTKS----VKAGRAEAALPLEER
LRRRIIDGERNGLEADLDEALAGR-PALDIVNDTLLEGMKVVGELFGSGQMQLPFVLQSAEVMKTAVAYLEPHMEKTD-DAGKGTIVLATVRGDVHDIGK
NLVDIILSNNGYTVVNLGIKQPVSAILEAAEEHRADVIGMSGLLVKSTVIMKENLEELNQRGLRFPVILGGAALTRAYVEQEGEVRYARDAFEGLRLMDA
LI-
>tr|F4F7P9|F4F7P9_VERMA Methionine synthase OX=263358 OS=Verrucosispora maris (strain AB-18-032). GN= PE=3 SV=1
---MLDALAD-RILITDGAMGTMLQAADLSLGGCNEILNVTRPDVVRGVHEAYLAAGADCIETNTFGANLPNLAEDIRIWELSEAGARLAREAADAPRWV
LGSIGPGTKLPT-LGHASYASLRDAYQQNAGGLIAGGADALIIETCQDLLQVKAAVIGSKRARQVPIICHVAVETGTMLLGSEIGAALTAIEPLGVDLIG
LNCSTGPAEMGEHLRYLSQHSTVPVSVMPNAGLPVL-TSDGAYFPLGPEDMAEALERFVDYGVALVGGCCGTTPEHIRVLAERLRDVAPVAREP--RIDA
GVSSIYHHVPFAQDASVLMVGERTNANGSKAFREAMLAADWQACVEIARSQARDGSHLLDLCVDYVGRDGTVDMRELAGRFATASTLPIMLDSTEPAVIE
AGLEMLGGRCVVNSVNFEDSRYARVMPVVAEHGAAVVALLIDEEGQARTAEWKVRVAERLINDLTRWGLRRADILIDALTFPIATGQEEGIETIEAIREI
ARRWGVNFTLGISNVSFGLNARQVLNSVFLHECVQAGLTSAIVHASKILPMAKIPALDLIYDRRDPVQRFIEVFEGVDAAS----ARATRAEAALPLNER
LKRRIIDGERNGLEADLDAAMAAG-APLAIINDILLDGMKVVGELFGSGQMQLPFVLQSAEVMKTAVAYLEPHMEKAD-DGGKGRIVLATVKGDVHDIGK
NLVDIILSNNGYEVVNIGIKQPISAILDAAEQHRADAIGMSGLLVKSTVIMKENLAEMASRGVRWPVLLGGAALTRAYVEDPGQVHYARDAFEGLSLMDR
VM-
>tr|E4N2M6|E4N2M6_KITSK Putative methionine synthase OX=452652 OS=A-0304 / NBRC 14216 / KM-6054) (Streptomyces setae). GN= PE=3 SV=1
---LREALAT-RVVVADGAMGTMLQAQDPSMQGCNEVLNVTRPDIVRSVHEAYFGVGVDCVETNTFGANHWALGEEIRIFELSEAGARIAREVADETRWV
LGSMGPGTKLPT-LGHTTFEVVREGFRQNAAGLIAGGVDALLIETSQDLLQTKASVLGCKAAVELPILAQITVETGTMLLGSETGAALTALEPLGIDFIG
LNCATGPEQYSEHLRYLAKNARIGLSAMPNAGLPIL-TKDGSHYPLSPVELADAQESFVDYGLALVGGCCGTTPEHLRHLVERVQGRPLTPRDP--RPEA
SAASLYQSVPFRQDTSYLAIGERTNANGSKKFRESMIAGDWQACVEIAREQIREGAHLLDLCVDYVGRDGVADMREIAGRLATASTLPIVLDSTEPPVLK
AGLEMLGGRAVLNSVNYEDTRFGKIASLAREHGAGLIALTIDEQGQARTAEHKVAIAERLIEQLGEYGIEESSILVDCLAFTLATGQEEGIETIEAIREL
KRRHNVQTTLGLSNISFGLNARQVVNSVFLHECVEAGLDSAIVHAAKILPMNRIPALDLVYDRRDPLQKLLQLFEGVSAAS----SAASRAEAALPLEER
LQRRIIDGERNGLEADLDAALLER-PALEIINGTLLSGMKTVGELFGSGEMQLPFVLQSAEVMKAAVAHLEPHMEKSD-SAGKGTIVLATVKGDVHDIGK
NLVDIILSNNGYNVVNIGIKQPVSAILEAAQEHQADVIGMSGLLVKSTVIMKENLEELNQRGLDFPVILGGAALTRAYVEQQGEVRYARDAFEGLRLMDA
LI-
>tr|J9WNQ2|J9WNQ2_STRTE Putative methionine synthase OX=1932 OS=Streptomyces tendae. GN= PE=3 SV=1
---FREALAT-RVVVADGAMGTMLQEQEPTLQGCNEILNVTRPDIVRSVHRAYFDAGVDCVETNTFGANHAALGEDIRVHELSRAGARVAREAADEPRWV
LGSIGPGTKLPT-LGHAPYTVLRDAYQQNAEGLVAGGADALLVETTQDLLQTKASVLGARRGLDVPLIVSVTVETGTMLLGSEIGAALTALEPLGIDMIG
LNCATGPAEMSEHLRYLARHSRIRLSCMPNAGLPVL-GTNGAHYPLTASELADAQENFVEYGLSLVGGCCGTTPEHLRQVVERVRGMAPAPRQP--QPEP
GAASLYQSVPFRQDTAYMAIGERTNANGSKKFREAMLEGRWDDCVEMARDQIREGAHMLDLCVDYVGRDGVADMDELAGRFATASTLPIVLDSTEVPVIR
AGLERLGGRAVINSVNYEDSRFAKVTALAREHGAALIALTIDEEGQARTVETKVAIAERLIEDLTNWGIQESDILIDTLTFTICTGQEEGIATIGAIREL
KRRRDVQTTLGLSNISFGLNARILLNSVFLDECVKAGLDSAIVHASKILPIARFSALDLIHDRRDPLQKLMALFEGATTKS----LKAGKAEAALPLDER
LKRRIIDGEKNGLDTDLAEALQTR-PALDIVNETLLDGMKVVGELFGSGQMQLPFVLQSAEVMKTAVAYLEPHMEKSD-AEGKGTIVLATVRGDVHDIGK
NLVDIILSNNGYNVVNLGIKQPLSAILEAAAEHRADVIGMSGLLVKSTVIMKENLQELNTRGLNYPVILGGAALTRAYVEQPGEVRYARDAFEGLSLMDA
LI-
>tr|A2AXF3|A2AXF3_STRCM Putative methionine synthase OX=1900 OS=Streptomyces cinnamonensis. GN= PE=3 SV=1
---LRQALAT-RVVVADGAMGTMLQAQDPTLQGCNEVLNVTRPDIVRSVHQEYFAAGVDCVETNTFGANHAALGEDIRIFELSQAGARIAREVAEEPRWV
LGSIGPGTKLPT-LGHTDFTTLRDGFQANAEGLIAGGADALIVETTQDLLQTKASLLGARRALDLPLVCSLAFETGTMLLGSEIGAALTALEPLGIDMIG
LNCSTGPAEMTEHLRYLARHCRVPLLCMPNAGLPVL-TKDGAHFPLDAAGLADAQESFVEYGLSLVGGCCGTTPEHLRQVVQRVSGLTPPARTP--HPEP
GAASLYQTVPFRQDTAYMAIGERTNANGSKKFREAMLEGRWDDCVEIAREQIREGAHMLDLCVDYVGRDGVADMAELAGRFATASTLPIVLDSTELPVLQ
AGLEKLGGRAVINSVNYEDSRFAKVTALAKEHGAALIALTIDEEGQARTAEHKVAIAERLIEDLTNWGIHEADILIDTLTFTICTGQEEGIATIEAIREL
KKRHDVQTTLGLSNISFGLNARVLLNSVFLDECVKAGLDSAIVHASKILPIARFDALDLIYDRRDPLQKLMELFEGVSTKS----MKAGKAELALPLEER
LQRRIIDGEKNGLEADLDEALQTT-PALDIVNNTLLEGMKVVGELFGSGQMQLPFVLQSAEVMKSAVAHLEPHMEKVEGAEGKGTIVLATVRGDVHDIGK
NLVDIILSNNGYNVVNLGIKQPVAAILDAAAEHKADVIGMSGLLVKSTVIMKENLEELNQRKMDYPVILGGAALTRAYVEQEGEVRYARDAFEGLRLMDA
LI-
>tr|D0GK40|D0GK40_9FUSO Methionine synthase OX=596323 OS=Leptotrichia goodfellowii F0264. GN= PE=3 SV=1
---LKKDLNG-KIVLLDGAMGTMIQKQNLTAGGCNDYLVLTKPEVIKNIHKMYLEAGSDIIETNTFGALDIVLRDELKVFEMNKSAAELVRKAIEENLYV
AGALGPSNKSISVTGGVTFDELIHTYYTATSGLLAGNVDIILFETIQDTRNLKAAYLGLQKAYNVPLMLSFTIETGTTLAGQTADAFYYAVNHMHPLSVG
LNCATGPEFMTQFLKILNNVSNTYISVYPNAGLPNE----EGKYEETPDTLSAKIEPFFNKYLNIVGGCCGTTPEHIKQIKEKSIK--YTPRIE----EH
SETNEVSGLITLNQNRPVYVGERTNVIGSRIFKNLIVNEKFDEATEVARLQIKGDADVIDVCLANPDRDEINDMKAFLEKVSKFAKVPIMLDSTDINVIK
EGLTYLQGKGIINSINLEEKKFVDMSELIKKFGASVVVGLIDEEGMAVSLEKKIKVAKRSYELLTKYGIDERDIIFDTLVFPVATGDQKAAATIEAIREI
KKEMNVKTILGVSNISFGLPGREVLNSYYMQKAYETGLDYAIVNTEKLIPLSEISSEALLF---DTVADFVAFYREKKGVE-------KKATTNMTPEEQ
VSNLVVEGSKKDLIPLLDTLLQK-YAPLDIINGPLMDGMDEVGKLFNNNDLIVAEVLQSAEVMKASVSHLEQFMEKSE-SSTKGKVIMATVKGDVHDIGK
NLVGIIIGNNGYDVVDLGINTPAEKIREAIINEKADFVGLSGLLVKSAAEMVNTVAVLREAGIKIPIFVGGAALTEKFTVNENIVIYSKDAMTALADLNK
MI-
>tr|D7GDP5|D7GDP5_PROFC Methionine synthase (5-methyltetrahydrofolate:L-homocysteine S-methyltransferase) OX=754252 OS=CIP 103027 / CIRM-BIA1). GN= PE=3 SV=1
---LREVLGH-EVILGDGAMGTMLQAAVLGPGGCNEILNVTRPDVILDIHRAYLAAGSDVIETNTFGANAAALGEGIRLAELAGAGARLARQAADEGHWV
FGSIGPGTKLPT-LGHIDFVTLRDAYYTQVSAMIDGGVDAVQIETCQDLLQAKAAVIGARRAVDLPIIVDITVETGTMLLGSETGAALTSLAPLGVDVIG
LNCATGPTEMSEHLRYLSAHADCAVMAMPNAGLPEL-TADGAVYPLGPDEFARAQLDYVRYGLAIVAGCCGTTPEHIARLRAALGARPVEHRDP--ELVN
TVSSLYSEVELRQETSYLAVGERTNANGSKAFREAMLAGDLETCIDLAKAQSREGAHCLDLCVDYVGRDGVDDMAELSQRFSTAVTLPVMLDSTEPEVIR
SGLEHLAGRCIINSVNFEDSRFARLMPIIAEHGAAVVALTIDEEGQARTAERKVAIAERLVDQLVTWGMDEGDILVDCLTFPIATGQEEGLETLNAISEF
KRRHRAGTTLGVSNISFGLNARVVLNSVFLHEAVEAGLDSAIVRAAKIMPMERIDALDLIYDRRDPLTRMLDMFAGVSSAD----VRAEHAEAALPLNER
LRQRIIDGDTNGLTDDLDEALRTR-GALDILNSDLLEGMKTVGELFGSGQMQLPFVLQSAETMKRAVAHLEPHMDSTD-EAGKGTLVLATVKGDVHDIGK
NLVDIIVSNNGYTVVNLGIKQPISAIVEAVKQNHADAIGMSGLLVKSTMVMKDNLAELDRLGVDFPVMLGGAALTRTFVEDSGQVRYAKDAFEGLSLMDS
VM-
>tr|G4CZ83|G4CZ83_9ACTO 5-methyltetrahydrofolate-homocysteine methyltransferase OX=997355 OS=Propionibacterium avidum ATCC 25577. GN= PE=3 SV=1
---LRTALSR-HVLVIDGAMGTMLQSSDLTIGGCNEILNVTRPDVISRIHDAYLDSGADIIETNTFGVNLPALTEGIRAVELASAATKLAREAADKPRYV
VGSIGPGTKLPT-LRQIGFAAIRDVYQQVIEAMIDAGADGVQIETCQDLLQARAAIIGAHRAVDLPILVDFTVETGIMLMGSESGAALTVLESLGVDAIG
LNCATGPAEMAEHLRTLSRGAQVPIMCMPNAGLPEI-TGEGARYPLGPDDLAPVLDDYVRYGLSVVGGCCGTTPDHIHAIAERVSGRPVPEREI--HHVD
AVASLYNDVPLSQDTAYLAIGERTNANGSKAFREAMLAQNWDECVDIARAQTRDGAHLLDLCVDYVGRDGVADMSELSARLATACTLPIILDSTEPDVLA
AGLEHLPGRCIINSVNFEDSRYQRVMPMVVENGAGVVALTIDEEGQARTAEWKVRVASRLIDDLVNWGMDIGDILVDCLTFPIGTGQEEGLETINAIAEI
KKRYGVRTTLGVSNISFGLNARIVLNSVFLHEAVKAGLDSAIVHTAKILPIDRIPALDLVHDRRDPLNRFLELFEGVTAAS----MRAEREEAAMPLFER
LKQRIIDGNAKGLEDDLDEAMESK-AALDIVNEDLLAGMQVVGDLFGSGKMQLPFVLQSAEVMKMAVAHLEPHMDKSD-TSGKGTLVLATVKGDVHDIGK
NLVDIIVSNNGYHVVNLGIKQPVTAIIEAAETHRADVIGMSGLLVKSTMVMKDNLLELNQTGLKYPVMLGGAALTRTFVEEEGEVRYARDAFEGLRLMDS
VM-
>tr|Q47NW1|Q47NW1_THEFY Methionine synthase (B12-dependent) OX=269800 OS=Thermobifida fusca (strain YX). GN= PE=3 SV=1
---FREVLGS-RVLVADGAMGTMLQTYDLSMGGCNEVLNITRPDVVREIHEAYLQAGVDCVETNTFGANFGNLGEGIRTYELAEAGARLAREAADAVRYV
LGSVGPGTKLPT-LGHAPYAVLRDHYEQCARGLIDGGVDAIVIETCQDLLQAKAAIVGARRATDTPIIVQVTIETGTMLVGSEIGAALTSLEPLGVDMIG
LNCATGPAEMSEHLRYLSHHSRIPLSCMPNAGLPEL-GADGAVYPLQPHELTEAHDTFIEFGLALVGGCCGTTPEHLAQVVERVQGRGVPDRKP--HVEP
AAASIYQSVPFRQDTSYLAIGERTNANGSKAFREAMLAERYDDCVEIARQQIRDGAHMLDLCVDYVGRDGVRDMRELASRLATASTLPLVLDSTEVAVLE
AGLEMLGGRAVLNSVNYEDSRFAKVAALAVEHGAALMALTIDEQGQARTAERKVEVAERLIRQLTEYGIRKHDIIVDCLTFTIATGQEEALETIEAIREL
KRRHDVQTTLGVSNVSFGLNARIVLNSVFLHECVQAGLDSAIVHASKILPINRIPALDMIYDRRDPLQRFLQLFEGVDAQA----MRASREEAALPLWER
LERRIVDGEAAGMEADLDEALTQR-SALDIINTTLLAGMKTVGDLFGSGQMQLPFVLKSAEVMKAAVAYLEPHMEKVD-GDGKGRIVLATVKGDVHDIGK
NLVDIILSNNGYEVINLGIKQPISAILEAAERHRADVIGMSGLLVKSTVVMRENLEEMNARGVRYPVLLGGAALTRSYVEQKGEVRYARDAFEGLKLMDA
IM-
>tr|A0LU36|A0LU36_ACIC1 Methionine synthase (B12-dependent) OX=351607 OS=Acidothermus cellulolyticus (strain ATCC 43068 / 11B). GN= PE=3 SV=1
---LRRELAR-RVLVADGAMGTMLQAADFTLVGCNEVLSLTRPDVVAAVHDAYLAAGCDAIETNTFGANLGNLGEGIRIEELAAAGARIAREVADRPRFV
LGSVGPGTKLPS-LGHVTFAELRDAYQRQVTGLINGGVDAVLVETAQDLLQAKAAVIGAKRAVDIPIFASVTVETGTMLLGSEIGAALTSLEALGIEMIG
LNCATGPAEMSEHVRYLAAHAAVAVSCLPNAGLPIL-GPDGAQYPLTPGELADALEEYAQFGLALVGGCCGTTPEHLRLVAERLRHRPIGSRRA--ETVP
AVSSLYQTVPLRQQTAFLAVGERTNANGSKAFREAMLAGRYEDCVELARGAARDGSHLIDVCVDYVGRDGVRDMRELARRLATATTLPVMLDSTEPAVIE
AGLECLGGRCIVNSVNFEDSRISRLMPIVREHGAAVVALTIDETGQARTAEHKVSVAERLIDTLTRWGMRETDILVDTLTFTLGTGQEEGIATIEAIREV
KTRHDVHTILGISNISFGLNARAVLNSVFLAECLRAGLDAAIVHPAKILPMSRIPALDVIYDRRDPLVRLMELFAGVTAAA----SQKSRAEAAMPLAER
LHRRIVDGERNGLEADLDEALTTR-RALDIINEILLPAMKEVGDLFGRGDMQLPFVLQSAEVMKAAVAYLEPHMEKSN-RSGKGTIVLATVKGDVHDIGK
NLVDIILSNNGYRVVNLGIKQPITAILEAAERHDADAIGMSGLLVKSTVVMRENLQEISSRGLRWPVLLGGAALTRAYVEDDGTVRYAKDAFEGLRLMDT
LM-
>tr|I6XPT7|I6XPT7_PROPF Methionine synthase OX=767029 OS=Propionibacterium propionicum (strain F0230a). GN= PE=3 SV=1
---LRDLLNS-RVLVADGAMGTMLQAQDLDLGGCNEVLNLTRPDVVSAVHRAYLEAGSDCVETNTFGTNLAALAEGIRLVELAGAGARIARETADGPRFV
LGSVGPGTKLPS-LGHIAFADIRDAYQAQVEAMIAGGIDAVQIETCQDLLQAKAAVIATKRAVDLPILVNVTVETGTMLLGSEIGAARSTLEALGVDVIG
LNCATGPAEMSEHLRYLSRNASCGIGAMPNAGLPEL-TPEGAVYPLGPDALADALATFLDYGLCVIGGCCGTTPAHIRLLAERFGGREVRPREV--TTER
TCSSLYVEVPFHQDLSYLNIGERTNANGSKAFREAMLAGNIDDCVEIAKGQARDGAHVLDLCVDYVGRDGISDMEELAGRLSTAVTLPIVLDSTEPQVLQ
AGLEKLAGRCVINSVNYEDSRFARVMPLVAEHGAAVVALTIDEEGQARTADWKLRVASRLIDELTTWGMDIGDILVDCLTFPIATGQEEGIETIEAIREL
KRRYGVRTTLGVSNVSFGLNARMVLNSVFLHECVAAGLDSAIVHSAKIIPMERIPALDLVWDRRDPLTRFLELFEGVTAAS----VRASRAEAALPLAER
LRRRIIDGEAKGLEADLDEALTGK-AALEIINEDLLAGMKVVGELFGSGQMQLPFVLQSAEVMKTAVSHLEPHIDKVE-GSGKGTLVLATVRGDVHDIGK
NLVDIIVSNNGYTVINIGIKQPIQAIIDAAETSGADAIGMSGLLVKSTLVMKDNLAELNRLGLKYPVLLGGAALTRAFVEHDGEVRYAKDAFEGLALMDA
VM-
>tr|D1A2R0|D1A2R0_THECD Methionine synthase OX=471852 OS=NCIMB 10081). GN= PE=3 SV=1
---LRQALRE-RVVVADGAMGTMLQAHNPTLGGCNEILNVTRPDIVRAVHAAYLDAGVDCVETNTFGANLGNLGEGIRIEELAEAGARIAREVADSPRWV
IGSIGPGTKLPT-LGHVSYGELRESYRRTAAGLIAGGAHALLVETCQDLLQVKAALNGAKQAADVVLIAQVTIENGAMLLGSEIGAALTALEPLGIDLIG
LNCATGPAEMSEHLRYLSRHARVGLSCMPNAGLPEL-TPDGARYPLTPQELADAHDAFTDYGLSLVGGCCGTTPEHLRLVVERVRGRELAPRRP--RPEP
GASSLYQHVPFKQDTSYLAIGERTNANGSKAFREAMLAERWDDCVRIARDQARDGAHMIDLCVDYVGRDGVADMKELAFRLATASTLPIMLDSTEPAVLR
AGLEMLGGRAVVNSVNYERSRFHRTMTAVREHGAAVVAMCIDEGGQARTREDKVRIACEIIEDLTNWGMRLEDIVVDCLTFPIATGQEEALETIEAIAEL
KRRYQVQTTLGISNVSFGLNARVVLNSVFLNECVNAGLDSAIVHASKILPMNRIPALDMVYDRRDPLQRFMELFEGVSAKE----LRASRAEAALPLWER
LKRRIIDGEANGMEADLDEALQSR-PALEIINDVLLDGMKTVGDLFGSGQMQLPFVLQSAEVMKAAVAYLEPHMEKSA-DGGKGRIVLATVKGDVHDIGK
NLVDIILSNNGYEVINLGIKQPISAIVEAAKEHRADVIGMSGLLVKSTVVMKENLEELNARGLQWPVLLGGAALTRAYVEQDGEVRYARDAFEGLRLMDA
FM-
>tr|C1F6A7|C1F6A7_ACIC5 Methionine synthase OX=240015 OS=Acidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / JCM 7670). GN= PE=3 SV=1
---FLEALKQ-RVLVYDGAMGTNIQKHALTLGGCNELLVLSRPDIIRDIHASFFAVGCDVVETDSFGSSRIVLAEDLQTRELNIAAAKLAREVADSPRFV
AGSIGPTTKLPS-LGHISYDDMALTYREQIEALIEGGVDVLLIETAQDLLQAKIALAACHDARHLPIQMQVTIETGTMLLGTEIGAALATLECFDPDIIG
LNCATGPAEMNDAVRFLCQNATRPVSVLPNAGLPQN-VGGHAVYALTPEELAKYHRSFVEYGVQVVGGCCGTTPEHLKAVVEAVDAKPAPRHVQ----PQ
VAASAFSALPLEVDGQPVIVAEEMNTTTREHFRNMVRAGDYDGILALAKKLVAEGSQMLDLCCAIVGEDEKAYMCSVLEKIATRVTAPILVDSTEADVIE
EGLKRIPGKPVINSINLEEKRTSQVLPMAKRYGAAVIALTIDEDGMALTAEKKVAVARRIHDLAVKYGLRPQDLIFDPLTLPISTGQEDGIETLEAVRRI
KQEIYVKTILGVSNISFGLNARRVLNSVFLKEAVDRGLDSAIVNYSKIYPLYKIPARRLVFYDTDPLQAYMAHFAGTKGKV----QD--DSEASLPVDET
LKQLIIGSNKRSLEEVLESALTD-WKPLDLINDVLLDGMKTVGELFGARKMQLPSVLDSAAVMKAAVAYLEPKMEREG-S-QRGTIVLATVKGDVHDIGK
NLVDIILSNNGFKVVNLGIKQPADTIIQAAREHKADAIGLSGLLVKSTLEMKYVVQDMQRLA-EIPVICGGAALTRKYVEESQGVFYAEDAFAGLHVMTD
IT-
>tr|J9DTL7|J9DTL7_9ACTN Methionine synthase I, cobalamin-binding domain OX=913338 OS=actinobacterium SCGC AAA027-L06. GN= PE=3 SV=1
---LREALNK-RVVIADGAMGTMLQNQNPTLNGCNEILNVTRPDIVKAVHVEYLNAGVDAIETNTFGANFANLAEGIRIFELSLAGAKIAREAADELRWV
LGSLGPGTKLPT-LGHTTYQNLKDAYATASKGLIEGGVDALLIETTQDLLQAKAAINGAREAKDVVLIAQVTVENGTMLMGSEIGAALNALEPLGIDLIG
LNCATGPAEMSEHLRVLSKGAAVGISVMPNAGLPVL-GKNGAHYPLTPIELASSLKQFVDYRVNLIGGCCGTTPAHMKEVVKQIHGTENSNRSI--IREI
GASSLYQFVGFKQDNTYLAIGERANANGSKAFKEALLREDWQSCVEIGRDQIRDGAHMLDLSVDYVGRDGVADMKELAFRFATTSTLPIVLDSTEPAVLK
AGLEQLGGRSVINSVNFEDSRFAKIMPLVVEHGAAVIALTIDEQGQARDADWKLRVSRRLVNDLTKWGMRTCDILIDCLTFPIATGQEEGIETLKAIRLL
KEEFEVQTTLGVSNISFGLNARIVLNSVFLAEAVKAGLDSAIVHPSKITPMNRIAALDLVYDRRDPLNKFLELFENVQVHS----SKESRAEAALPLEER
LQRRIIDGEKVGLPEDLQTALASGIPALTIINDYLLSGMKTVGELFGKGEMQLPFVLQSAEVMKTAVAYLEPHIEKTD-DKGRGKILLATVKGDVHDIGK
NLVDIILSNNGYDTVNIGIKQTVNEIIDAALKNDVDVIGMSGLLVKSTVIMKENLQELENRGMKWPIVLGGAALTRSYVEQPGTVRYAKDAFEGLKLMDL
LM-
>tr|E1RBM2|E1RBM2_SPISS Homocysteine S-methyltransferase OX=573413 OS=Spirochaeta smaragdinae (strain DSM 11293 / JCM 15392 / SEBR 4228). GN= PE=3 SV=1
---FRSLLGK-RIIIFDGAMGTSIQALEIPDGGCNEILNKTAPEYIDAIHDSFLAAGADVVETNSFGATSIVLDDDLQSADLNRRAAEIARKAAGRPRFV
AGSMGPGTKLPT-LGHITFDELYTAFRKQADALLEGGADLLVVETSQDLLQTKAAVIAAGDSRDIPIIASVTVESGTMLMGSDLSAVVATLHPLRTDLIG
INCAVGPDLMGPNLEQLASIYNGPIFCMPNAGLPEM-KDGKTVYSLGPVQFAEIMAGYLRFHIAVAGGCCGTTPEYIRQLALRAEKMRPAPTSPM---RP
VLSSLFSAQPMIQEPAPFLIAEQANSNGSKVFRGMIDQEDWDAAADFLLDQTGYGAHAADLCVAVPGRNERSDMLNILNGAAARNRLPFVIDSTDPQVIE
TALKAIGGRPLINSINLEEEHAQKVFALAARYGAAIICLTIDEEGMAKTVEKKVAIARRLAAIARHAGLRNEDLVFDPLTFTLGSGDESGTESIRALSAI
KEAVGCLTVMGVSNISFGLAARRVLNSLFLSEAVSAGLDMAIVNPKKIRPVAALDALDLIYHNESALLRYLELFEGKGISE----EENKEKQS-LPPQEL
LRSRVIAGSKDRLEEIINRCLETT-AAGDIINEILIPAMGIVGERFGKGEMQLPFVLQSAEVMKRSVSILEPHMEKGD-SSKRGTVILATVAGDVHDIGK
NLVDIILSNNGYLVKNLGIKIGIDTIIKAAEEEKATAVGMSGLLVKSTAIMKSNLEEMKRRKLRLPVLLGGAALTPAFVEGPAEVYYCKDAFDALKALDS
LK-
>tr|D7B417|D7B417_NOCDD Methionine synthase OX=446468 OS=JCM 7437 / NCTC 10488) (Actinomadura dassonvillei). GN= PE=3 SV=1
---FRETLSR-RVVVADGAMGTMLQAHDLDLGGCNDILNLTRPDIVRDTHAAFLAVGSDAIETNTFSANLGGLAEGIRTYEIAHAGAQVAREAADAPRYV
LGSVGPGNRLPT-LGHAPYTQLRDYYEQCARGLIDGGSDAILIETCQDLLQVKAAVVAAQRARDVPIIAQVSIENGTMLLGSEIGAALTSLEPLGVDVIG
LNCSTGPAEMSEHLRYLSHHSPIPISCMPNAGLPQL-GPDGAFYDLSPAELADAHDSFTEFGLSLAGGCCGTTPEHLRHVVERVQGRGIKNRKP--LVEA
ASSSLYQSVPFRQDASYLAVGERTNANGSKKFREAMLEGRWDDCVEIARDQIRDGAHLLDLNIDYVGRDGVSDMRELASRLATSSTLPIMLDSTEPPVLE
AGLEALGGRSVVNSVNYEDSRFTRIMGLVKEHGAAVVGLCIDEEGQARTAEWKVRVATRLIEQITEWGLNTSDIMIDCLTFPITTGQEEGLETINAIREL
KRLYDVQTTLGLSNLSFGLNARIVLNSVFLHEAVQAGLDSAIVHASKIVPINQIPALDMVYDRRDPLSRFMEMFEGVDAKS----MKASRAEAALPLWER
LERRIIDGEMTGIEADLDEALESK-PALAIVNDTLLSGMKTVGELFGSGQMQLPFVLKSAEVMKGAVAYLEPHMEKSD-DDGKGRIVLATVKGDVHDIGK
NLVDIILSNNGYDVVNIGIKQPVSAILEAAEEQRADVIGMSGLLVKSTVIMKENLEEMNSRGLRFPVLLGGAALTRSYVEQDGHVRYAKDAFEGLRLMDA
FM-
>tr|D6YBK6|D6YBK6_THEBD Methionine synthase OX=469371 OS=JCM 10125 / NBRC 14880 / R51). GN= PE=3 SV=1
---FREALSE-RILVADGAMGTMLQSYHPTIGGCNDVLNVSRPDIVRSVHDAYLAAGVDCIETNTFNSNQAALGEGIRIYELSEAGARLARERADHPRYV
LGSMGPGTKLPT-LGHLPYALLRDAYEQNAAGLIAGGVDALIIETCQDLLQAKAAIVGAKRARDVPIIAQVTIENGTMLLGTEIGAALTSLEPLGIDLIG
LNCATGPAEMSEHLRYLAKHARVPLSCMPNAGLPEL-TAEGARYPLQPEELAEAHVTFIEFGLSLVGGCCGTTPEHMRTVVERVAGMTRSARRP--RPEA
GAASLYQHVPFRQDTSCLMIGERTNANGSKAFREAMLAGQYDECVEIARAQARDGAHMLDLCVDYVGRDGVADMKELAFRFATASTLPIVLDSTEPAVLE
AGLEMLGGRAVVNSVNFEDSRFTKVMRLVKEHGAAVVALTIDEEGQARTAEWKVRVATRLIEKLVEWGMRPEDILVDCLTFPIATGQEDALETIEAIREV
KRRYDVQTTLGISNVSFGLNARVVLNSVFLNECVNAGLDSAIVHASKILPMNRIPALDLIYDRRDPLQRFMELFADADAAS----MTAGKAEAALPLWER
LKRRIIDGERKGLEDDLDEALTQR-PALEIINDVLLDGMKTVGDLFGSGQMQLPFVLQSAEVMKSAVAYLEPHMERVE-GVSKGRIVLATVKGDVHDIGK
NLVDIILSNNGYEVINLGIKQPISAIIQAAEEKQADVIGMSGLLVKSTVVMKENLEELNARKLKYPVILGGAALTRAYVEQEGEVRYARDAFEGLRLMDA
IM-
>tr|D2ATZ7|D2ATZ7_STRRD Methionine synthase OX=479432 OS=NI 9100). GN= PE=3 SV=1
---FREVLAE-RVMVADGAMGTMLQAHDVTLGGCNEVLNATRPDIVRAVHDAYFEVGVDCVETNTFGANLAALGEDIRTHELSEAGARVAREAADHPRYV
LGSIGPGTKLPT-LGHKPYGVLRDAYYDNAAGLIAGGADALIIETCQDLLQVKAAVIGAKRARDVPVIAQVTVENGAMLLGSEIGAALTAIEPLGVDVIG
LNCATGPAEMSEHLRYLSRHARLQLSCMPNAGLPQL-TSDGAYYPLTPDELADAHENFTSFGLSLVGGCCGTTPEHLRKVVERVRGNGHSPRRP--RPEA
GAASLYQHVPFRQDTSYLAIGERTNANGSKAFREAMLAENWEECVEIARAQARDGAHMLDLCIDYVGRDGVRDMKELAFRFATASTLPIVLDSTEPAVLE
AGLEMIGGRAIINSVNYEDSRFTRIMKLVRSHGAAVMALTIDEEGQARTAEWKLRIATRLIEDLTNWGMNVEDIIIDALTFPIATGQEEGVETIEAIREL
KRRYGVQTVLGLSNISFGLNARIVLNSVFLNECVNAGLDSAIVHASKILPMARIPALDMVYDRRDPLQRFMELFEGVDAAS----IKADRAELGLPLWER
LKRRIIDGERKGLEADLDEALAQR-PALEIVNDVLLDGMKTVGELFGSGQMQLPFVLQSAEVMKTSVAYLEPHMDRVE-GENKGRIVLATVKGDVHDIGK
NLVDIILSNNGYEVVNLGIKQPVSAILEAAEEQKADVIGMSGLLVKSTVIMKENLEEMNSRGMRFPVLLGGAALTRAYVEQQGDVRYARDAFEGLRLMDA
FM-
>tr|F2RH40|F2RH40_STRVP 5-methyltetrahydrofolate--homocysteinemethyltrans ferase OX=953739 OS=JCM 4526 / NBRC 13096 / PD 04745). GN= PE=3 SV=1
---LREEFAR-RVVVADGAMGTMLQAADPSMGGCNEILNLTRPDIVASVHDAYFSVGVDCVETNTFGANLAALAEGIQVYELSEAGARIARAAADAPRWV
LGSMGPGTKLPT-LGHVTYEPLREAFQQNAEGLIRGGADALLIETSQDLLQTKAAVIGARRAVDLPVIVQVTVETGTMLLGSEIGAALTALEPLGIDMIG
LNCATGPAEMAEHLRYLSRHARVPLSVMPNAGLPVL-TSDGAHYPLSPAELADAQEAFVEYGPALVGGCCGTTPEHLREIVGRVRGAAVLDRRP--EPEP
GASSLYSHVPFRQDTAYLAIGERTNANGSKKFREAMLEARWDDCVEMARDQIREGAHMLDLCVDYVGRDGVADMQELAGRFATASTLPIVLDSTEVDVLR
AGLEKLGGRAVVNSVNYEDSRFAQVTALAKEHGAALMALTIDEEGQARTVGAKVAIAERLIADLTNWGIRESDILIDTLTFTICTGQEEGVATIEAIREL
KRRHDVQTTLGLSNISFGLNARIVLNSVFLDECVKAGLDSAIVHASKILPIARLEALDLIHDRRDPLQRFLEMFEGATAKS----LKAGKTELALPLDER
LKRRIVDGEKNGLEADLDEALTTT-PALDIVNNILLDGMKTVGELFGSGQMQLPFVLQSAEVMKTAVAYLEPHMEKSD-ADGKGTIVLATVRGDVHDIGK
NLVDIILSNNGYNVVNIGIKQPVSAILEAAEEHKADVIGMSGLLVKSTVIMKENLQELNGRGLRYPVILGGAALTRAYVEQEGEVRYARDAFEGLRLMDA
LM-
>tr|C7LY65|C7LY65_ACIFD Methionine synthase OX=525909 OS=103882 / ICP). GN= PE=3 SV=1
---YEELLRE-RVVVFDGAMGTNLQLAGLGAGGCNEILVVTRPEAVAAVHDSFLAVGVDVVETDTFGALAPVLAEGIRAYELNLRAAQLARDVASGPRFV
AGSMGPGTKLPS-LGQIPFEDLRDAYEVQAEGLIAGGVDLLLVETVYDLLSAKAAVIGARRARSVPVQVQVTIETGRMLPGTEVGAALAALERLDPVAIG
INCATGPEEMGEHLRYLSEHQRVPISCLPNAGMPHV-VDGHMHYDLTPDALAAAHRRFVELGVGIVGGCCGTRPEHLRAVVEAVEAVPRERHPT----PR
QVASLYQAVELRQDLAITAVGERTNANGSRRFRDAMLARDWDTCVRMAQDQVRDGAHMIDLCVDYTGEDGTVAMEELSSRLATASTLPIMIDSTEAAVVE
TALRHLGGRPIINSVNLEETRFDSFLRLAKDYGAAVVATCIDEEGQARTAARKVEIAKRIVALAVRYGLATDDIIIDPLVLPVTTGMEEALETIEALRRI
TAEMGVSTLVGLSNVSFGINAREALNSVFLAECQAAGLSMAILHPSRIQPLARIPCLDLIYDRRDPLARLIERFADVQA-V----AV--TGEEALSVPER
LHRRIVDANRQGLEDDLAAALGEGMSALGVINDVLLPAMAEVGDLFGSGQMQLPFVLASAETMKQAVAWLEPYLDRSV-N-DRGTVVLATVQGDVHDIGK
NLVDIILTNNGYRVVNLGIKVALSEMLAAAEEHHADAIGMSGLLVKSTLVMRDNLVEMNERG-HLPVILGGAALTRTFVERDGRVFYGKDAFEGLDVLER
LG-
>tr|E6W3E3|E6W3E3_DESIS Methionine synthase OX=653733 OS=Desulfurispirillum indicum (strain ATCC BAA-1389 / S5). GN= PE=3 SV=1
---LRQRAAS-HILCLDGATGTALASFELTAGGCNEYLVITRPDVVEGVHRRYLEAGADIIETNSFGSTSIVLREALQVHRLNLEAARIARTMADRPRFV
AGCMGPTSKSICITGGVTFHELRDAFRQQALALIEGGVDYLLLETMQDTLNLKAGLIGATEAVDMPLAVSVTIEMGTMLAGQAIEALYNSIEHFPLLYVG
LNCATGPDFMTGHIRSLAQLATCGVACVPNAGLPDE----NGRYQQSPTDVAGKLAQFMEGWLNFVGGCCGTTDEHIRMISAE-AA--KRPATP----QP
ATPFALSGIEYLPPGELYLVGERTNVIGSRKFKRLIAEGNLDEAVEVARKQIRGGAHIIDVCLANPDRDEHTDMQAFMAALMRSIKVPFMIDSTDAAVVE
VALQYSQGKAIINSINLETERLDEVVPLLKTYGAAVVVGTIDEDGMAVTAQRKLEIARRSYDILVRYGLRPENIVFDPLVFPVATGDEQARETIEGIALI
REEFHCAITIGLSNVSFGLPAREILNAVFLKHCVDAGLTMPIINPEMMVRYASIEAENLIF---DPITPFADKFRERKTQQ-------KATDESLPVAQR
LQSNIVEGSRENLHPRLDEAMAQ-MPPLDVINGPLMAGMAEVGRLFNDNKLIVAEVLQSAEVMKASVDYLSQFMEADQ-VTTRGTMVLATVKGDVHDIGK
NLVDIIMTNNGYKVINLGIKIPSEQIIEAIEKHKPDFVGLSGLLVRSAQQMTTTAADMKAAGIDIPLMVGGAALSENFTSQEGLAIYCRDPMECLALAGR
LL-
>tr|J7L8Z3|J7L8Z3_NOCAA Methionine synthase OX=1205910 OS=Nocardiopsis alba (strain ATCC BAA-2165 / BE74). GN= PE=3 SV=1
-------------------MGTMLQAHDLDLGGCNDILNLTRPDIVRDTHAAFFEVGSDCVETNTFSANYGGLIEGIRTYEIAEAGARIAREAADEPRYV
LGSVGPGTRLPS-LGHSPFALLRDYYEQAGRGLIDGGADAILIETCQDLLQVKAAVIGAKRARDIPIIAQVAVESGTMLMGSEIGAALTSLEPLGIDVIG
INCSTGPAEMSEHLRYLSHHSPIPISCMPNAGLPEL-GPDGAVYNLSPEDLTDAHDTFTEFGLSLVGGCCGTTPEHLRQVVERVQGRGIKNRRP--LVEP
STSSLYQSVPFRQDASYLAVGERTNANGSKKFRKAMLAEDWDACVEMARDQIRDGAHVLDLNIDYVGRDGVADMRELAFRFATASTLPLMLDSTEPPVLE
AGLEALGGRAVINSVNYEDSRFTRIMRLVSEHGAAVVGLCIDEEGQARTAEWKVRVATRLIEQLTEWGMRTGDIVIDCLTFPITTGQEEGIETLEAIREL
KRRYEVQTTLGLSNLSFGVNARIVLNSVFLHEATQAGLDSAIVHASKIVPINQIPALDLVYDRRDPLSTFIDMFEGVDAKS----MKASRAEASLPLWER
LERRIIDGELTGIEADLDEALAER-PALAIVNDTLLEGMKTVGELFGSGRMQLPFVLKSAEVMKAAVAYLEPHMEKTD-DDGKGRIVLATVKGDVHDIGK
NLVDIILSNNGYEVVNLGIKQPVSAILEAAEEKRADVIGMSGLLVKSTVIMKENLEEMNSRGMRFPVLLGGAALTRSYVEQSGEVRYAKDAFEGLRLMDT
FM-
>tr|Q83X55|Q83X55_STRRO Probable 5-methyltetrahydrofolate-homocysteine S-methyltransferase OX=1928 OS=Streptomyces rochei (Streptomyces parvullus). GN= PE=3 SV=1
------------MVVADGAMGTMLQAQDPTLQGCNEILNVTRPDIVRSVHEAYFAVGVDCVETNTFGANHAALGEDIRVHELSAAGARVAREVADEARWV
LGSMGPGTKLPT-LGHAPYRTLRDAYQANAEGLVEGGADALLVETTQDLLQTKAAVLGARRAADLPVIVSVTVETGTMLLGSEIGAALTALEPLGIDMIG
LNCATGPAEMSEHLRYLARNARVPLSCMPNAGLPVL-GKDGAHYPLSPGELAEAQGTFVENGVSLVGGCCGTTPEHLRQVVERVRGLAPSARDP--RPEA
GAASLYQSVPFRQDTSYLAIGERTNANGSKKFREAMLEARWDDCVEIAREQIREGAHMLDLCVDYVGRDGVADMAELAGRLATASTLPIVLDSTEVDVIE
AGLERLGGRAVINSVNYEDSRFARVTALAREHGAALIALTIDEEGQARTAGHKVAIAERLIADLTNWGIRESDILIDTLTFTICTGQEEGVATIEAIREL
KRRHRVQTTLGLSNISFGLNARILLNSVFLDECVKAGLDSAIVHASKILPIARFSALDLIYDRRDPLQKLMQLFEGATAKS----LKAGKAEAALPLEER
LKRRIIDGERNGLEADLDTALRER-PALDIVNETLLDGMKVVGELFGSGQMQLPFVLQSAEVMKAAVAHLEPHMEKSD-ADGKGTIVLATVRGDVHDIGK
NLVDIILSNNGYNVVNLGIKQPVSAILEAAEEHRADVIGMSGLLVKSTVIMKENLEELNQRDLTYPVILGGAALTRAYVEQQGEVRYARDAFEGLRLMDA
LI-
>tr|E4TJJ8|E4TJJ8_CALNY Methionine synthase (B12-dependent) OX=768670 OS=Yu37-1). GN= PE=3 SV=1
---FVKFAKD-RVILFDGAMGTNIQKYSISDGGCNEYLNIVAPHIIEEIHGNFLEAGADVLETNSFGGTRLVLSEGLAVYEINLQAARIARRVADK-RFV
AGSVGPGTKLVS-LGHISYDDLFYMYKEQSLALIDGGVDLFIIETCQDMLQIKAAINGIRSGVNLPIMVSVTVENGTMLTGSDLSAVAVTMAGYPIYSLG
INCALGPDLMYEPLTTLSNSWGGRISCIPNAGLPMN-INGKFVYNMEPDRMAEIIDDILHFPISIVGGCCGTSYEHIREMRKVCDKHKVPDPVRF-QV-K
GAASIYTATSLNQEPPPALIGERANANGSKAFRELLIKEDFDGMLKIVKDQEEEAAHFVDICVAYAGRDEKRDMARFISMVNRMSLLPAVIDTTEPDVLE
EALKRYSGKPIINSINFEGKKLHRVLNLVKDFPAAVIGLTIDEDGMAMTAAKKFEIAKRIYTVFTEYHLDPEDLIIDPLTFSIGSGDETALQTLEAIKMI
KNELGVKTVLGLSNVSFGLSSRIILNSVFLKKAVESGLDMAIVHASKILPEASIPALNLING--GALEKFINFYSAKKDDD----ISVDKN---ISDEEL
LIVKLKKGDKTDIETLLDRLLKR-YTPYDIINNILMSGMQEIGELFGKGKMLLPFVLQSAEVMKKSVSYLEKFMEKTD-TEPKGKIVLATVKGDVHDIGK
NLVDIILSNNGYRVYNLGIKVPVEEMIEKAIEVGADAIGMSGLLVKSTIIMKENIEEIKRRGLKVKVLLGGAALTEGYVKNDGEVYYCKDAFDAITY---
-L-
>tr|D3P8U9|D3P8U9_DEFDS 5-methyltetrahydrofolate--homocysteine methyltransferase OX=639282 OS=101012 / SSM1). GN= PE=3 SV=1
---LRNYTSD-KILLFDGGMGTTIQQYDIPSGGCNEILNLTYPELIEEIHTKFYEAGADIVETNSFGASRLVLSEGLKVYEINLNAAKIARKAANK-KFV
AGSIGPGTKLPS-LSQISFDDLYKMYKEQILGLIDGGVDLLLIETCQDLLQVKSVVIAAFDLLDIPVSVSVTIENGTMLLGTDLSAVITVLRDYPIFSLG
INCAVGPDLMYEPLSQLAKLWDRKISCIPNAGLPQN-INGKFIYDLTPEKMAEIMADLCQFNLDFIGGCCGTTYEHIAALRMVANSFKPKPKVKY-EY-Q
GVSSLYTSTKLRQEPPPTLIGERANANGSKAFRELLIAEDFDGMLAVAKEQENNGAHLLDVCVAYAGRDETKDMAKFVSMLNNAINIPLVIDSTEPKVLE
EALKRYAGKPVINSINLEGTKLHQILEIVRKHPAAVIALTIDEEGMAMTAEKKFEIAKKIYNIWTDYNFNPEDIIFDPLTFSIGSGDETAKETLEAIKKI
KSELGAKTVLGVSNVSFGLSAREVLNSVFLQEAVKYGLDLAIVNPAKIIPIHKINCLDLIYN--NALTNFLEYFSKRTDIK----EDNDSI---IPPEEQ
LKNKLISGDKSKLESLLDNLLVK-YKPIEIINKILIPAMKEVGDLFGAGKMLLPFVLQSAEVMKKSVLYLEKFMDKKD-DENKGVIVLATVKGDVHDIGK
NLVDIILSNNGYKVYNLGIKVPVEEMIKKAKEVNADAIGMSGLLVKSTIVMKENIEEIRRSQLKTKILLGGAALTEGYVKNKGKVFYCRDAFDAIKF---
-L-
>tr|F8E4D9|F8E4D9_FLESM Methionine synthase OX=717231 OS=Flexistipes sinusarabici (strain DSM 4947 / MAS 10). GN= PE=3 SV=1
---FRKFAEK-NIVVFDGGMGTTIQNESIPEDGCNEYLNISAPEIMKNIHRKYFQAGADVAETNTFGATRLILSEGLQVYEINVAGAKLARGAADE-KFV
FGSMGPGTKLPS-LSQISFDDLYEMYKEQSKGLMDGGVDGLIVETSQDLLQIKSALKAIFDNIDLPVCVSITVETGTMLVGSDISAAAALIGSYPVFSLG
LNCGLGPDMMHKPLSELTKYWNRSVSCIPNAGLPEN-VNGKTVYTMTPGKMAEIFKGLLELPLNIIGGCCGTGYEHIKQLKNIAKSINPSKPSG--TA-A
ASSSLYSSTSLTQTPPPAIIGERANANGSKAFRELLLNNDYEGMLNVAKEQEDAGAHFIDVCVAYAGRDEMFDMQHFVSLLNKTLSAPIVIDSTEPPVIE
TALKNYSGKPIINSINLEGGKLHKILKLVHDYPANVIALTIDENGMAMTADEKFKIAEKIYNIWTQYNLAPEGLIFDPLTFSIGSGDTSAVETLNAIKMI
KDRLGAKTVLGVSNVSFGLSSRIFLNAVFLEEAVENGLDMAIVHASKLINLSSMDCKNLIYG--NALNEFISHFSGKSLQR----EEEVEE---ITEEEA
LVKKLKKGDKKDLEKIIDTLLQK-YKPFEIINDILMPGMKEIGELFGSGKMLLPFVLQSAEVMKKSVTYLKKFINKED-TETKGKVILATVKGDVHDIGK
NLVEIILSNNGYEVYNLGIKVSVDEMIERAKEVKADAIGMSGLLVKSTGIMKENIAEIAQRQLDTTVLLGGAALTEGFVKNKGKVHYCADAFSALKY---
-L-
>tr|D4H5Z8|D4H5Z8_DENA2 Methionine synthase OX=522772 OS=Denitrovibrio acetiphilus (strain DSM 12809 / N2460). GN= PE=3 SV=1
---FNEFAKN-RIILFDGAMGTSIQNYEITDGGCSEWLNVAAPEIIQQIHEQYFEAGADVVETNTFGGTELVMSEDLRTYELNLLGAQIARRAADK-KYT
AGSIGPGTKLPS-LGQISYDDLYTMYHSQAEALLEGGVDLFIIETCQDLLQIKSALNAVIDVSDAPVMVSITVENGTMLMGTDISAAVTLLREYPVFSLG
LNCSTGPDLMHNPINDLAQNFNGRISCIPNAGLPEN-RGGQMVYDMTPDKMAKIVEGMVEFPIGVLGGCCGTTPEHIKALRPIADKYKPNKPQAK-EY-T
GSSSLYVSTTLMQTPPPALIGERANANGSKAFRELLLAEDFDGMLAVAKEQEETGAHFIDACVAYAGRDEKADMAKFMHLLNKTLTAPVVIDSTEPDVVE
TALKSCAGKPVINSINFEGEKLHIILRAVKKHPASVIALTIDEDGMAMTAEKKFEIAERIYNIFTEYGLNPNDLIFDPLTFSIGSGDKTAIQTNKAIKMI
KEKLGAKTALGLSNISFGLSSRPILNSVFLHEAVEHGLDMAIVHASKVMPQAAIPSKDLLAG--GALSAFIEHFSKKEGIV----QQEEKT---LPPDEM
LKNLIKKGRKAGLEETLTALMQT-MKPIEIINNIMLDTMKEIGELFGAGKMLLPFVLQSAETMKTAVTVLEPFMEKSD-TETRGRIVLATVKGDVHDIGK
NLVDIILSNNGYEVYNLGIKVSVEEMIAKAVEMDADAIGMSGLLVKSTNIMRENIAEINRQGLSKKVLLGGAALTEKFVKNPGMVSYCRDAFDALKV---
-L-
>tr|H6SN06|H6SN06_RHOPH Methionine synthase (B12-dependent) OX=1150469 OS=Rhodospirillum photometricum DSM 122. GN=RSPPHO_00256 PE=3 SV=1
-SRFLDALRE-RVLLCDGGMGSLVQAMDLSVENCTEALTLARPDVVRGLHARYFEAGADCVETNTFGGSILTLAEDLRTREINRRSVELAREAAEGERFV
LGSVGP-GTRLPSLGHVDYDTLKDSLTEQCLGLIEGGADAILIETCQDPLQFKAAINAAKKARDTPILLQVTVETGTLLVGADIAAAATVAHALGVDSLG
LNCATGPREMSEHVRWLAENWPGFISLQPNAGLPEL-VDGKAHYPLTPAELADWHKRFIEDGVNLVGGCCGTTPPHIQAVDAMLRTRPPVRRTV--HWVP
SVASLYGAVPLRQENAFLSIGERCNANGSKKFRTLQDAEDWDGIVGMAREQGREGSHTLDVCTAFVGRNETRDMTEVITRLRGSVHMPLVIDSTETKVLA
AALKLYGGKAILNSINFEEETAAQRLELAREFGAAVIALTIDEEGMAKDADSKLRIARRLYEFATEHGLAPEDLLFDPLTFTICTGNEDGLETLNAIRQI
REQMGCQIILGLSNISFGLKARCVLNSVFLDEAVKAGMTGAIVHVSKILPLHKIAALNLIHDRREPLHAFIRLFEDRVEA-----KAEAR-AD-APVDER
LRQRIIDGDRLGLEADLEEARALM-PPLEIINTILLDGMRVVGELFGAGKMQLPFVLQSAETMKAAVSHLEPHMEKI-EGQERGIMVLATVKGDVHDIGK
NLVDIILSNNGYKVVNIGIKQPLPAILDAARTHKADAIGLSGLLVKSTVIMKDNLEEMARDGWDVPVVLGGAALTRAFVEEDGRVAYARDAFDGLDLMAK
VM-
>tr|C7JFY7|C7JFY7_ACEP3 Methionine synthase OX=634452 OS=Acetobacter pasteurianus (strain NBRC 3283 / LMG 1513 / CCTM 1153). GN= PE=3 SV=1
-LPLLDALRD-QVLLCDGGMGSRIQMLDLDVQNCTEILTLSRPELIREIHRGYFEAGADMVETNTFGGSPITLGESLKAREINKNSAILAREAAESTRYV
LGSMGP-GTKLPSLGNIDYDSLEAALAEQARGLIEGGVDAILIETCQDTLQIKAAVNGVKIARTTPIFVQVTVETGTLLVGPDIAAAATVIHSLDVDLMG
LNCATGPQEMAEHVKWLSENWPRLISVQPNAGLPEL-VNGQTHYPLTPAEMATWVERFIEDGLNLIGGCCGTSTPHTEALDAMLRRRPPVPRTS--VWVP
SVASLYSQVPLRQENAYFSIGERCNANGSKKWRELQEAHDWDGCVTVGREQIREGSNALDICTAFVGRNERAEMDEVIKRFTSSVNAPLVIDSTETPVIE
AALKLHGGKPIINSINFEEGPASDRMELARKFGAAVVALTIDEKGMARKPEDKLRIASRLVEFAEKYGLPQSDLMIDPLTFTIATGAEDGQWTLEGIKMI
RDAFDIQIVLGLSNISFGLNARAVLNSVYLDHAVKAGMTAAIVHVSKIRPLHLIVAEDLIFDRRTPLQTLLAMFADRKAA-----DAVKRKRA-ETAEER
LKDRIVDGDRKGLEADLEEAMQNM-APLDIINTVLLDGMKVVGELFGAGKMQLPFVLQSAETMKAAVAYLEPHMERI-DGQQRGTIVLATVKGDVHDIGK
NLVDIILTNNGYRVVNLGIKVPVQDMIDAARKEKADAIGMSGLLVKSTVIMRENLEEISRAGLDTPVLLGGAALTRNYVEEDGRVAYARDAFDGLTLMDQ
IS-
>tr|Q2RU64|Q2RU64_RHORT Methionine synthase (B12-dependent) OX=269796 OS=Rhodospirillum rubrum (strain ATCC 11170 / NCIB 8255). GN= PE=3 SV=1
-SRFLDHLRN-RVLLCDGGMGSLVQAMDLSVDNCTEVLNLSRPDVVRDIHTRYFAAGADCVETNTFGGSTLTLAEDLRTREINRRAAEIAREAAESDRFV
LGSIGP-GTKLPSLGHIDYDTLKDAITVQCEGLIEGGADAILVETCQDPLQFKAAINAAKAARDTAILLQVTVETGTLLVGADIAAAATVAHALGVDSLG
LNCATGPQEMSEHVRWLKENWPGLISLQPNAGLPEL-LDGKTHYPLTPAELADWHGRFIEDGVNLIGGCCGTTPDHIAAVNAMLETRPPVKRSV--HWVP
SVASLYGAVPMRQENAFLSIGERCNANGSKKFRTFQDNEDWDAIVGMAREQVKEGSHTLDVCTAFVGRKEGADMTEVVSRLRGGVNAPLVIDSTETPVLT
QALKLYGGKAIINSINFEEESAAQRLALAREFGAAVIALTIDEEGMAKDAEAKLRIAHRLYDFATQHGLPASDLMFDPLTFTICTGNTDGLETLDAIRRI
RTELECQIILGLSNISFGLKARHVLNSVFLDKAVEAGMTGAIVHISKILPLHKIAAEDLIFDRRAPLHAFIALFEDRSET-----KVAVK-RA-ETVEER
LKQRIVDGDRLGLDADLTEAMGKY-PPLEIINSLLLDGMKVVGELFGAGKMQLPFVLQSAETMKAAVAFLEPHMEKI-EGQEKGIIVLATVKGDVHDIGK
NLVDIILSNNGYKVINIGIKQPIAAILASARENRADAIGMSGLLVKSTVIMKDNLEEMAREGWNTPVLLGGAALTRAFVEEDGRVAYARDAFDGLDLMAK
VA-
>tr|Q2WA92|Q2WA92_MAGSA 5-methyltetrahydrofolate--homocysteine methyltransferase OX=342108 OS=Magnetospirillum magneticum (strain AMB-1 / ATCC 700264). GN= PE=3 SV=1
-TNILDHLSR-HVLLCDGGTGALVQAMNLSVENCTEILVKSRPDVIRGIHARYFEAGADMVEADTFGASPITLAEGIRAHELNQAAIELAWEAAEQTRFV
LGAIGP-GTKLPSLGHIGYDELEAAYVIQAAGQIAGGVSAFLVETCQDPLQIKAAVNGCKIANDVPVFVQVTVETGTLLVGADIAAAATVVQSLGVPLMG
LNCAAGPQEMGEHFKWLIDNWTGFVSIQPNAGLPEL-VDGQTRYPLLPAELAVWHERFVSAGANLLGGCCGTTPPHISATNEMLKRRPPVKRSV--HWVP
SVASLYTQVPLRQENAFLSIGERCNANGSKKFRDLQDAEDWDGITAIAREQVKEGSHTLDVCTAFVGRNEVADMTEVVSRLRGAVTTPLVIDSTELPVLE
AGLKLYGGKAILNSINFEEKDAADRLVLARKFGAAVVALTIDEDGMAKDAAAKLRIAKRLYDFATKHGLPASDLLFDPLTFTICTGNEDAVETLDAIEMI
TREMECGIVLGLSNVSFGLKARQVLNSVFIDHAIKRGMTGAIVHVSKIVPLHTLAAEDLIYDRDPALSRYIALFGDRKAA-----EIKKE-RP-AKAEDR
LKQRIIDGDRTGLEDDLAQVMEEW-KPLDIINTLLLDGMKVVGELFGSGKMQLPFVLQSAETMKASVAFLEPHMEKA-DGQQKATMVLATVKGDVHDIGK
NLVDIILTNNGYKVINIGIKQPVAEIIKAAKEHKADAVGMSGLLVKSTVIMRENLEEMTNAGLDVPVLLGGAALTRKYVEEDGRVAYARDAFDGLDLMAK
VA-
>tr|H8MHK1|H8MHK1_CORCM 5-methyltetrahydrofolate--homocysteine methyltransferase OX=1144275 OS=/ M2) (Myxococcus coralloides). GN= PE=3 SV=1
-EALKAAMRE-RILVLDGAMGTLLQGHQLVAAGCNEHLVLTRPDVIEGIHAKYFAAGADVTETDSFGGTPVVLAEELKAMEINIAASRLALNAAKAMRWV
AGSIGPTTKAISVTGGITFEELVDNFAVQAEGLAVGGSDYLLVETAQDTRNVKAALLGIDRAFKLPVAVSGTIEMGTMLAGQSVESLATSLEHTDLLYLG
LNCATGPDFMTDHIRSLSSMSPFPVSCVPNAGLP----DENGQYLESPEMISRSLRRFCNGWINVVGGCCGTHAGHIEALAAMVKGLKPRTETP--KPRS
SL-SGVDYLEVTDEQRPIIVGERTNVIGSKKFKELIVAGAFDDASEIARAQVRRAAQVIDICLANPDRDELEDMRHFLEVVVKKVRVPLMIDSTDEKVIA
MALTYCQGKAIINSVNLEEERFEKVVPLAKAFGAALVVGCIDEVGMAVTRDRKLAVAERSYDLLQKYGMRPEDLYFDPLVFPCASGDAQGVETIEGVRLI
KQRFQCRTVLGISNVSFGLPGREVLNSVFLYHCVQAGLDMALVNSEKLERYPSLLSEDLIYNRGQPVTPFAAHFRERKPA-----RAQVSSLP---LNER
LQRYIIEGTRDGLTADLDLAMKEM-SPLDIINGPLMKGMDEVGRLFGANELIVAEVLQSAESMKAAVSHLEPHMSQT-QTASRGKIVLATVKGDVHDIGK
NLVEIILANNGFQVVNLGIKVPPEQLVLAVKEHRPDILGLSGLLVKSAHQMVATAEDLKRAGVETPILVGGAALSRNFVDRNGTVAYAQDAMNGLELAKQ
IV-
>tr|F0IZ81|F0IZ81_ACIMA Methionine synthase OX=926570 OS=Acidiphilium multivorum (strain DSM 11245 / JCM 8867 / AIU301). GN= PE=3 SV=1
-PSLLEALRH-RVLLCDGGMGSRVQALTLDTENCTEVLNLSRPDLVREIHRGYYEAGADMVETNSFGGSPITLAEELRAREINRIAAELAREAAETDRYV
IGSVGP-GTKLPTLGNIEYDPLEAGLAEQCRGLIEGGVDAILIETCQDTLQIKAAVNGARIARDTPIFVQVTVETGTLLVGPDIAAAATVIQALDVPLIG
LNCATGPQEMAEHVRYLAQNWPGLISVQPNAGLPEL-VDGKTHYPLTPDELATWLERFIEDGINLIGGCCGTSTPHIAALDAMLRRRPPVPRKP--VWIP
SVASLYGSTPLRQENAYFSIGERCNANGSKKWRELQERHDWDGCIAMGREQVAEASNALDICTAFVGRDELGEMSEIITRFTSSVNAPLVIDSTETPVIE
AALKLHGGKPIINSINFEEHIAEERMLLARKFGAAVIALTIDETGMAKEPAQKLEIATRLVDFARKHGLPQSDLLIDPLTFTIATGNEDGLWTLEGIRLI
RDAFDIQIILGLSNISFGLNARAVLNSVFLDHAVKAGMTGAIVHVSKIRPLHLIVMEDLIFDRRRPLQRVLEMFADRKAA-----DAVKKVKA-DTVEGR
LRDRIVDGDRKGLADDLDEAMKSH-APLDIINNLLLDGMKTVGELFGAGKMQLPFVLQSAETMKAAVAYLEPYMERV-EGQQKGTIVLATVKGDVHDIGK
NLVDIILTNNGYRVVNLGIKVPLADMVAAAKEHRAHAIGMSGLLVKSTVVMRENLEEMSRQGLDIPVLLGGAALTRNYVEEDGRVAYARDAFDGLHLMDR
VT-
>tr|Q08RV5|Q08RV5_STIAD Methionine synthase (B12-dependent) OX=378806 OS=Stigmatella aurantiaca (strain DW4/3-1). GN= PE=3 SV=1
-EALRAAMRE-RVLVLDGAMGTLIQAQNLKMAGCNEHLVLTRPDVIQGIHAEYFAAGADVTETDSFGGTPLVLAEGLKALEINIQASRLARQAAADMRWV
AGSIGPTTKAISVTGGITFDELVNQFAAQTEGLAIGGSDYLLVETCQDTRNVKAALLGIERAFALPVAVSGTIEMGTMLAGQSVESLAASLEHVELLYLG
LNCATGPEFMTDHLRSLSGMSPFAVSCVPNAGLP----DENGNYLESPEMLARSLRRFCHGWLNVVGGCCGTRPSHIRAIAEAVKGLRPRSATV--RPRS
TL-SGVDFLEVTDELRPIIVGERTNVIGSKKFKELIIAEQYEDASEVARAQVKRGAQVIDICLANPDRDELEDMNRFLDVVVKKVRVPLMIDSTDEKVIE
RALTYCQGKAIINSVNLEEERFEKVVPLARQYGAALVVGCIDEVGMAVTRQRKLEVAQRSVELLGKYGMKAEDLYFDPLVFPCASGDAQAVETIEGVRLI
KQRFQCKTVLGISNVSFGLPGREVLNSVFLYHCVQAGLDMALVNSEKLERYPSLLAEDLLYNRGAPVTPFAAHFRERKPQ-----KAATSSLP---LEER
LQRYIIEGSRDGLFADLDLAMEKY-GPLEIINGPLMKGMDEVGRLFGANELIVAEVLQSAESMKAAVGHLEPRMSQT-QTATRGKIVLATVKGDVHDIGK
NLVEIILANNGFQVVNLGIKVPPEQLVQAVREHRPDMLGLSGLLVKSAHQMVATAEDLKRAGVEVPILVGGAALSRNFVDKNGTVAYAQDAMSGLDLAKQ
IV-
>tr|I3TIS7|I3TIS7_TISMK 5-methyltetrahydrofolate--homocysteine methyltransferase OX=1110502 OS=Tistrella mobilis (strain KA081020-065). GN= PE=3 SV=1
-SRLLDFLGS-NVLLLDGGMGSQLQARDLSVDNCSEILNLSRPDIIRDIHTAYFEAGADAVETNTFGGSPITLGEDLQAFEINVKACELAHEAAERERFV
IGSIGP-GTRLPSLGHIDYDRMEAALTIQARGLIAGRADAFLIETCQDPLQIKAAVNAVKIARDLPIMVQVTVEVGTLLVGTDIAAATAIVDALDVDVMG
LNCATGPQEMQEHVRYLSQTWRRRISVLPNAGLPEL-VDGRTHYPLGARELAQWLERFIEDGIDIVGGCCGTGPDHIRAIDEMLRRRPPVKREV--NWMP
GAASLFGFVPYFQENAYFSIGERCNANGSKKFREMQDAGNWDGCVGMAREQVKEGSNAIDLCAAFTGRNEIADMTALTTAMRGSVSAPLVIDSTELNVIE
TTLKLYGGKPIINSINFEEEPARARLALAKKFGAAMVALTIDEEGMAKTADRKLAIAERLYALADEYGLAPEDLLFDPLTFTIATGNEDGIETLEGIRLI
RERFRCQIILGLSNISFGLKARHVLNSVFLDYALKAGMSGAIVHLSKLMPLHKIVAEDLIFDRRAPLISFMALFADRKAE-----SQATKVRP-ETVEER
LKLRIIDGDREGLGADLDEAMAKM-PPLEIINTVLLDGMKVVGELFGAGKMQLPFVLQSAETMKAAVAWLEPHMEKV-EGEQKATIVLATVKGDVHDIGK
NLVDIILTNNGYRVVNLGIKQPVASIIQAAREHRADVVGMSGLLVKSTVIMRENLEEMTREGLDVPVLLGGAALTRKYVEEDGRVAYARDAFDGLSLMNA
VV-
>tr|B3E428|B3E428_GEOLS Methionine synthase OX=398767 OS=Geobacter lovleyi (strain ATCC BAA-1151 / DSM 17278 / SZ). GN= PE=3 SV=1
-NPVLQALSQ-CILILDGAMGTQLQARNLTAAGCNEMLVLTRPDVIEDVHKAYLEAGADIVETCSFGSTDIVLAEGLKVFELNKAAALVARKACDAPRFV
AGSMGPTTRTISVTGGVTFEQLVTAFRDQTIGLLAGGVDLLLLETAQDTLNLKAGAEGIRLAFRVPLMVSGTIETGTMLAGQNVEALYASLTHLELISIG
LNCATGPEFMTDHLRALSELATCHISVYPNAGLP----DENGNYAESPDSLAQKLSRFVEGWLNIIGGCCGTSPAHIAAIANMAAGRQPRKPVT--IRRR
LV-SGIEPLFIEEDNRPILVGERTNVIGSRKFKNMIVAGQFEEAAEIARAQVKTGAQVIDICVANPDRDELADMEQMLVYLPKKVRAPIMIDSTDAKVTE
LALQRLQGKCVINSINLEEERFAKVAPLLRHYGGAVVVGCIDENGMAVTRQRKLEVAQRSYDLLNKYGLRPEDLIFDPLVFPVGSGDDNAVETIEGVRLI
TETFQCSTILGISNVSFGLPGREVLNAVFLYHCVKAGLGYAIVNTEKLERYASILAEDLIFWRGAPVAAFAAAFRDKKPS-----HAPAAELP---LDER
LPLYIIEGSKDGLTADLDAALTRD-KPLEIINGPLMAGMAEVGRLFNDNQLIVAEVLQSAEAMKAAVSHLEPHLSKD-ETSSKGKMLLATVKGDVHDIGK
NLVEIILSNNGFEVINLGIKVGPEELIAAAKKENPDFIGLSGLLVKSALQMIVTAADLKAAGIDAPLLVGGAALSRAFADTRGPVLYAKDAMAGLELANQ
LV-
>tr|A6QBA6|A6QBA6_SULNB 5-methyltetrahydrofolate--homocysteine methyltransferase OX=387093 OS=Sulfurovum sp. (strain NBC37-1). GN= PE=3 SV=1
-ETIKSLLEK-RILVIDGAMGTQIQDL--DVPGCNELLNDTAADLIKRIHKRYAMAGADLIKTNTFGTMPWVLDEQMRAYELSKKGAELVKEICAEPKFV
LGSIGP-GTKLPSLGHIHYDEMYEGYKTVALGLIDGGCDVFLLETCQDPLQIKAALHACQDANELPVMVSVTIESGSMLIGTDATTIVTIMEPFDILSLG
FNCGTGPDQVKKHLKTLSELCSIPISVHANAGLPQN-RGGYTYYPMGPDEFTQKQLEFTFDGVSFLGGCCGTTPQHIQALKKAVE-TIPKKPTG--SIEP
SIASLFTTTELFQKPAPLLIGERSNATGSKAFRELIIAGDYEGTLTVGQAQVRDGAHCLDVNVEFAGRNGATDMSAVMELYNQKIPLPLMPDATRVGTME
AALKCIGGKPIINSVNLEEGKLDAICQLAKKYGTALVCLTIDETGMAKTTEEKLRVAERIYDLCNRHGIDPRNLIFDMLTFTVGSGDLEAIQTLEAIREL
HKRHEVGSTLGLSNISFGLDARIYLNSVFLHHCIQAGMTSVIINVKHIVPLAKMICEELLFR--PSLFRFIEHFSDKTVD-----DSGTDEEYEMNSEEK
IAKLLLDGDKERMIPLVEEARKEI-DPDRIVNEILIDAMKVVGELFGSGQMQLPFVLQSAETMKATVDYLNPYLTKQ-EKETDTTLVIGTVKGDVHDVGK
NLVDIILSNNGFKVINVGIKTDLDTYLEAHKEHKVQAIGMSGLLVKSTAVMKDNLETMAEMGMTIPVLLGGAALTRSFVDDFGPIFYCRDAFDGVIVMSR
IE-
>tr|D5QB96|D5QB96_GLUHA Methionine synthase OX=714995 OS=Gluconacetobacter hansenii ATCC 23769. GN=GXY_01936 PE=3 SV=1
-PHLLDALRD-QVLLCDGGMGSRVQLLDLEVENCTEILNLSRPELVREIHRGYFEAGADMVETNSFGGSPITLGEGLRAREINRTAAHLAREAAEQHRYV
VGSVGP-GTKLPSLGNIDYDTLESGLAEQCRGLIEGGVDCLLIETCQDTLQIKAAVNAGKIARDTPIFVQVTVETGTLLVGPDIGAAATVVNALDVPVMG
LNCATGPQEMAEHVRWLSENWPGMISVQPNAGLPEL-VNGKTHYPLTPQDMATWVERFIEDGLNLIGGCCGTSTPHTQALDAMLRRRPPVPRRP--VWIP
SVASLYSQVPLRQENSYFSIGERCNANGSKKWRQLQEAGDWDGCVAVGREQAAEGSNALDICTAFVGRDEMREMNEVITRFTSSVNAPLVIDSTETPVIE
AALKLHGGKPIINSINFEEAAANDRLKLARKFGASVIALTIDEVGMAKTAEDKLRIATRLVDYANQHGLPQADLMIDPLTFTIGTGVEDGLWTLEGIRLI
HERFDIQIVLGLSNISFGLNARAVLNSVFLDHAVRAGMTAAIVHVSKIRPLHLIVAEDLIFDRRAPLQRMLELFADRKAA-----DAVKKVRA-ETAAER
LKDRIVDGDRKGLEDDLAEAMRDM-APLDIINTVLLDGMKVVGELFGSGKMQLPFVLQSAETMKAAVAWLEPHMERK-EGQARGTMVLATVKGDVHDIGK
NLVDIILTNNGYRVINLGIKVPVADMIAAVREHGADAIGMSGLLVKSTVIMRENLEEMNRQGIETPILLGGAALTRNYVEEDGRVAYARDAFDGLSLMDK
VV-
>tr|Q5FP86|Q5FP86_GLUOX 5-Methyltetrahydrofolate-S-homocysteine methyltransferase OX=290633 OS=Gluconobacter oxydans (strain 621H) (Gluconobacter suboxydans). GN= PE=3 SV=1
-PHLLDALAD-QVLLCDGGMGSRVQMLDLEVENCTEILNLSRPELVREIHRGYFEAGADMVETNTFGGSIVTLAEGLRTREINRTAATLAREAAETHRYV
MGSIGP-GTKLPTLGNIAYDDLEAGLVEQCRGLIDGGVDGFLIETCQDTLQIKAAVNAAKIARDAPIFVQVTVETGTLLVGPDIAAAATTVQALDVPSLG
LNCATGPQEMGEHVRWLSENWPGLISMQPNAGLPEL-VDGKTVYPLSPEEMAVWMERFVEDGLNLIGGCCGTSTPHIQALDGMLRRRPPVKRST--IWMP
SVSSLYTQTPLRQENSYFSIGERCNANGSKKWRELQEANDWDGCVAIGREQAAEGSNALDICTAFVGRDEVREMNEVVTRFTSSVNAPLVIDSTETPVIE
AALKLHGGKPIINSINFEEQQAHDRMKLARKFGAAMIALTIDEVGMAKEPQDKLRIAERLVDFANQYGLPQSDLMIDPLTFTIATGVEDGQWTLEGIKLI
RDKFDIQIILGLSNISFGLNARAVLNSVFLDHAVKAGMTGAIVHVSKIRPLHLIVAEDLIFDRRTPLQKLLELFAGRKAA-----DAVKKRRA-ETPAER
LKDRIVDGDRKGIEQDLEDAMAEM-PPLDIINNVLLDGMKVVGELFGSGKMQLPFVLQSAETMKTAVAWLEPHMERV-EGQHRGTMVLATVKGDVHDIGK
NLVDIILTNNGYQVINLGIKVPLADMIAAVKEHKADALGMSGLLVKSTVIMRENLEEMHRQGFDVPVILGGAALTRNYVEEEGRVAYARDAFDGLGLMDK
IA-
>tr|E6X0N2|E6X0N2_NITSE Methionine synthase (B12-dependent) OX=749222 OS=Nitratifractor salsuginis (strain DSM 16511 / JCM 12458 / E9I37-1). GN= PE=3 SV=1
-DRIREIIAE-RYLVIDGAMGTQIQDL--KVPGCNELLNATAPELIGRIHKRYAMAGADMIKTNTFGAMPWVLDEGLRAYELSRKGAELVKAVCEEPRFV
LGSIGP-GTKLPSLGHIDYEAMYEGYLETARGLIDGGCDVFLLETCQDPLQIKAALHACEAANSLPIMVSVTIESGSMLIGTDAATIVTILEPFDILSLG
FNCGTGPDQVKKHLKTLSERCKFPISVHSNAGLPQN-RGGHTFYPMGPDEFAKKELEFIFDGVAFLGGCCGTTPQHIQALAKAIE-GKPKSPTG--SIPP
SIASLFESVELFQDPAPLLIGERSNATGSKAFRQLILDEDYEGTLTVAQEQVRAGAHALDVNVEFAGRDGAKDMKEVISLYNQKIPIPLMPDATNVHTME
VGLRRIGGRPIINSANLEIERFDRICRLAKKYGAALVLLTIDETGMAKEKERKVEVAERMIERANLHGLRKEELIVDVLTFTVGSGDEEAVQTLEAIREL
HKRHELGTTLGLSNISFGLAARVYLNSVFLHHCVEAGLSSVIINVKHIVPLSRMVCEELLFH--ASLFRFIEHFSDKSLE-----TEQTDEEYELSTEEK
IQKLLMDGDKERLIPLVEEARHEL-GADRIVNEILIDGMKVIGELFGSGQMQLPFVLQSAETMKATVDYLNPYLTKQ-EKESDTTLVIGTVKGDVHDVGK
NLVDIILSNNGFKVKNIGIKVELEQFLEAYEEVNADAIGMSGLLVKSTQVMKENLEELARRGIEIPIIMGGAALTRGFVDDYGPIFYCRDAFDGVVAMSR
IE-
>tr|A9H4J4|A9H4J4_GLUDA Putative methionine synthase OX=272568 OS=PAl5). GN= PE=3 SV=1
-PHLLDALRD-QVLLCDGGMGSRVQVLDLDVENCTEILNLSRPELVREIHRGYFEAGADMVETNSFGGTPITLGEGLRAREINRTAAHLAREAAESHRYV
IGSVGP-GTKLPSLGNIDYDTLEAGLAEQCRGLIDGGVDALLIETCQDTLQIKAAVNGAKIARDTPIFVQVTVETGTLLVGPDIAAAATAIHALDVPLMG
LNCATGPQEMAEHVRWLAGNWPGLISIQPNAGLPEL-VDGQTHYPLSPADMATWVDRFIEDGLNLVGGCCGTSTPHIAALDAMLRRRPPVPRRP--VWIP
SVSSLYTQVPLRQENSYFSIGERCNANGSKKWRTLQEEGDWDGCVSIGREQVAEGSNALDLCTAFVGRDEMREMNEVVTRFTSSVNAPLVIDSTETPVIE
AALKLYGGKAIINSINFEEGHATDRMLLARKFGAAVVALTIDEVGMAKTAEDKLRIATRLVEFADRHGLPQSDLMIDPLTFTIGTGVEDGLWTLEGIRQI
RDRFDIQIVLGLSNISFGLNARAVLNSVFLDHAVRAGMTAAIVHVSKIRPLHLIVAEDLIFDRREPLQRLLELFADRKAS-----DAVKKTRS-DRVDER
LKERIVDGDRKGLEADLDEAMRTI-PPLDIINTILLDGMKVVGELFGAGKMQLPFVLQSAETMKAAVAHLEPHMERA-EGQTRGTIVLATVKGDVHDIGK
NLVDIILTNNGYRVVNLGIKVPVADMIAATREHAADAVGMSGLLVKSTVVMRENLEEMARQGLDVPVLLGGAALTRNYVEEDGRVAYARDAFDGLSLMDQ
VA-
>tr|I2K6M5|I2K6M5_9PROT 5-methyltetrahydrofolate--homocysteine methyltransferase OX=1165841 OS=Sulfurovum sp. AR. GN=SULAR_05898 PE=3 SV=1
-ETIKSLLQE-RILVIDGAMGTQIQDL--KVPGCNELLNDTAPELIGRIHKRYAMAGADLLKTNTFGTMPWVLDEDMRAYELSKKGAQLVKEVCNEPKFV
LGSIGP-GTKLPSLGHIHYDEMYEGYKLVALGLIDGGCDVFLLETCQDPLQIKAALHACQDANQLPIMVSVTIESGTMLIGTNAETIVTILEPFDILSLG
FNCGTGPDQVKKHLKTLSELWHGPISIHANAGLPQN-RGGYTYYPMGPDEFTEKQLEFTYDGVSFLGGCCGTTPQHIQALKKEAE-VIPKKPTG--SIKP
SVASLFNTVELFQEPAPLLIGERSNATGSKAFRELILASDYEGTLTVGQAQVRDGAHMLDVNVEFAGRDGAKDMRAVMELYNQKIPLPLMPDATRPNTIE
EGLKCIGGKPIINSTNLEEENFATYCKLAKKYGAVLVCLVIDEEGMARTKEKKVAVAKRMYELANTHGLEPQNIMFDMLAFTVGTGEEEGKNAYEAIKEI
HEIYEVGSTLGLSNISFGLEARFYLNSVFLHHCVQAGMTSVIINVKHIIPLAKMICEELLFT--PSLFKFIDHFADAVVE-----DEGADEAYEMSHEEK
IKKLLMDGDKERMLPLVEEARHEI-HPDVIVNEILIDAMKVVGELFGSGQMQLPFVLQSAETMKTTVDYLNPYLTKQ-EKETDTTLVIGTVKGDVHDVGK
NLVDIILSNNGFKVVNVGIKTELQEYLDVIEKQPIQAIGMSGLLVKSTAVMKENLETMAEMGMEIPVLLGGAALTRSFVDDFGPIFYCRDAFDGVIAMSR
IE-
>tr|K2K367|K2K367_9PROT B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase OX=1207063 OS=Oceanibaculum indicum P24. GN=P24_06192 PE=3 SV=1
-SRFLKALEE-RVLLGDGAMGTRVQAADLDVDNCTEILNRSRADLVRDIHAGYLEAGSDAVQTNSFGGSPITLAEDLEAFELNRTAGILAREAIERERFV
LGSIGP-GTKLPSLGHIAYQPLEDAFALQSAGLIAGGIDAFLIETCQDPLQVKAAVNGAKRANDIPIMVQVTVETGTMLVGTDIAAAATIIDALDVPVIG
LNCATGPQEMAEHVHWLAENWRGRISIQPNAGLPEL-VDGQTVYPLAAPELATWLERFLEDGISFVGGCCGTQIEHIQALDAMLRRRPPKTRSP--LWTP
SVASLYGPVALRQENAFFAIGERCNANGSKKFRELQDSGDWDGCVEMGRDQVREGSHSLDVCTAFVGRDEVADMTEVVSRMRGSVDSPLVIDSTELIVLE
AALKLYGGKAILNSINFEEEPAEKRMELARRFGTAVIALTIDEEGMAKTVERKVEVAKRLHDFAVKHGLPASDLMFDPLTFTICTGNEDGLWTLEAIERI
AQELECQIVLGLSNISFGLNARHVLNSVFLDHAVKRGMTGAIVHVSKIMPLHQIAAEDLIFDRRSPLQAFMALFEGRQSA-----AKVEKKRA-ETVEER
LKERIIDGDRKGLDDDLAEAMKSH-PPLDIINTYLLDGMKVVGELFGAGKMQLPFVLQSAETMKAAVAYLEPHMERV-EGQEKGTIVLATVKGDVHDIGK
NLVDIILTNNGYKVVNLGIKQPIATIIQAAEEHKADAIGMSGLLVKSTVIMRENLEEMTRLGMKTPVMLGGAALTRNYVETDGQVAYARDAFDGLNLMNK
VI-
>tr|E4TXB2|E4TXB2_SULKY Methionine synthase (B12-dependent) OX=709032 OS=YK-1). GN= PE=3 SV=1
-NTLLETISR-RPLIIDGAMGTQLQERADKIPGCNELLNVTCPEVMSDIFHAYLTAGADLITTNTFGAFSWVLDEGIRAYELSRAGAAVCKAECDKPRYV
LGSIGP-GTKLPSLGHIHYDEMYEGYLECCLGLIDGGCDIFLLETCQDPLQIKAALHACEAANALPIMVSVTIEAGSMLIGTDAATIATIMEPFDIISLG
FNCGTGPEQYAKHVRTLSEVWGKPISVHANAGLPQN-RGGYSYYPMGPDEFANLQRDFLYDGVSFLGGCCGTTPQHIRALVDKVS-RVPKKPSG--ETKP
SIASLFNTVELIQTPAPLLIGERSNSTGSKAFRELIIASDYEGTLSVGQAQVRDGAHCLDVNVEFAGRDGAVDMSHVMRLYNQKIPLPLMPDATRVNTME
EALKCIGGKPIINSVNLEEERLDAICSLAKKFGTALVCLVIDEKGMAKTTEDKMRIADRIYDLCNRHGIDPRNLMFDMLTFTVGSGDLEAIQTLEAIRQL
HFKYNVGSTLGLSNISFGLSARVFLNSVFLHHCIEAGMTSVIINVKHIIPLSKMICEELLFH--PSLFKFIGHFSDKTID-----NSKNDEAYELSDEEK
IAKLLLDGDKERMIPLVERVRLTI-SPDKIVNEILIDAMKVVGELFGSGKMQLPFVLQSAETMKTTVDYLNPYLSKQ-EKDTDTTLVIGTVKGDVHDVGK
NLVDIILSNNGFKVINIGIKTELEEYLEVMKSKDIHAIGMSGLLVKSTQVMKDNLETMAGMGITTPVLLGGAALTRSFVDDFGPIFYCRDAFDGVIAMSR
IE-
>tr|H0A3M2|H0A3M2_9PROT 5-methyltetrahydrofolate--homocysteine methyltransferase OX=1054213 OS=Acetobacteraceae bacterium AT-5844. GN=HMPREF9946_03415 PE=3 SV=1
-PHLLDALRD-RVLLCDGGMGSRVQALTLEIENCTEVLNLSRPELVREIHRGYYEAGSDMVLTNSFGGSPITLEEELRAFEINKLSVELAREAADSDRWV
VGDIGP-GTKLPSLGHIDYDTLEAALTEQCRGLIAGGADALLTETNQDTLFIKAAVNAAKIAKDIPIFVQVTVETGTLLVGSDIAAAATAIHALDVPLIG
LNCATGPQEMAEHVRWLSQNWPGLLSCQPNAGLPEL-VDGKTHYPLGAEEMASWMQRFVEDGLNLIGGCCGTSIPHIQGLDAMLRRRPPAQRQS--YWVP
SVASLYGQVSLRQENSYFSIGERCNANGSKAWRERQAAHDWDACVSIGREQVGEGSNSLDVCTAFVGRDEKAEMDEVIRRFTGSVNAPLVIDSTETPVIE
SALKLHGGKPIINSINFEEGHATDRMVLAKKFGAAVIALTIDEVGMAKTPEDKLRIAERLVDFANKHGLPQSDLLIDPLTFTIATGNEDGLWTLEGIRMI
REKFDIQIILGLSNISFGLNARHVLNSVFLDHAVKAGMTGAIVHVSKIKPLHSIVAEDLIFDRREPLQKLLEMFAGRKAA-----DAAKKVKA-DTVEGR
LKDRIVDGDRKGLDEELADALKGI-KPLDIINGILLEGMKVVGELFGAGKMQLPFVLQSAETMKAAVAYLEPHMEKI-EGQEKGTIVLATVRGDVHDIGK
NLVDIILTNNGYRVINLGIKVPLNEMIAAVQEHKANAIGMSGLLVKSTVVMKENLEEMSRQGLEVPVLLGGAALTRNFVEDDGRVAYARDAFDGLHLMDR
VM-
>tr|G6F1B2|G6F1B2_9PROT 5-methyltetrahydrofolate-S-homocysteine methyltransferase OX=1088868 OS=Commensalibacter intestini A911. GN=CIN_12650 PE=3 SV=1
-NKLLEKLQQ-QILLCDGGMGSIVQMLDLDIQNCTEVLNLSRPDLVRDIHRQYFEAGADMVETNSFGGSITTLSEDLQTREINKRAAEIAHEAADLERFV
VGSIGP-GTRLPSLGNIAYDPLEASITEQCRGLIDGGVNCFLIETCQDPLQIKAAVNAAKIAQFLPIFVQVTIETGTLLVGSDIAAAATVIDALDVQMMG
MNCGTGPREMGEAIKWLSQYWPRLISMQPNAGLPEL-LDGKTHYPLSPEEMGHWMARYIEQKINMIGGCCGTNPKHIAAMDQVLRERPAIPRTH--IAMP
AVASLFSSTPLRQENSLFSIGERCNANGSKKWRDLQAEQDWDGCVTVGREQLKEGSNALDVCMAFVGRDEIAEMGEIIPRFTSSINAPLVIDSTGSDVIE
ACLKLHGGKPIINSINFEEEIAAERMVLAKKFGAAVVALTIDEVGMAKTPEDKLRIATRLVEFADRYGLPQSDLMIDPLTFTIATGVEDGLWTLEGIKAI
HDKFDIQIVLGLSNISFGLNARAVLNSVFLYHAQQAGMTSAIVHVSKIRPMHLIVIEDLIFDRRTPLKKVLEIFADRKAS-----QAVARPVA-TTIEEQ
LHDRIVDGNRKGLEDDLNKAMEKY-EPLEIINTLLLSGMKTVGELFGSGKMQLPFVLQSAETMKASVSFLEPFMEKT-SDDAKGTMVLATVKGDVHDIGK
NLVDIILSNNGFNVVNLGIKVPVADMITAAKEHKADAIGMSGLLVKSTVIMRENLEEMAEQGLNVPVLLGGAALTRAYVEEDGLVAYARDAFDGLTLMEK
IA-
>tr|Q30NX6|Q30NX6_SULDN Methionine synthase (B12-dependent) OX=326298 OS=(Thiomicrospira denitrificans (strain ATCC 33889 / DSM 1251)). GN= PE=3 SV=1
-EYILKTIKN-RPLIIDGAMGTQLQQRDDKISGCNELLNVTAPEILSEIFHAYLTSGADFVTTNTFGSFSWVLDEQIRAYELTYAGAKLAKDECKKPRFC
LGSIGP-GTKLPSLGHITYDEMYKGYTEFCLALIDGGVDVFLLETAQDPLQIKAALHACNEASEIPIMVSVTIESGTMLIGTDAQTIATILEPFDILSLG
FNCGTGPEQVLKHVKTLSEIWHKPISVHANAGLPQN-RGGYTYYPMGPDEFAAKQQSFLFDGVSFLGGCCGTTPQHIRALVNLVS-DIPKAPSG--KHEN
SLASLFSTVPLMQESSALLIGERSNATGSKAFRELLLAEDYEGTLSVAQQQVRAGAHVLDVSVGFAGRDETKDMNRVMSLYAQKIALPLMPDSTQTAALE
EALKLIGAKPIINSVNLEIEKFDAVCSLAKKFGAALVCLTIDEIGMAKSVERKLEVAERIYDLANKHGIRAENLVFDLLTFTLGSGDEEGINTIEAIREL
RRRHEVGATLGLSNISFGLDARPYLNSMFLHHCNEAGLTSVIINVAHIIPINKIICDNLIFNRKPALFEFIDHFSTKAVD-----NNAVDEAYLMSDEEK
IAKLLMDGDKDRMIPLVEEARHKV-APEKIVNEILIDAMKVVGELFGSGQMQLPFVLQSAETMKKTVDYLNPYLPKI-DKSVDTTLALGTVKGDVHDVGK
NLVDIILSNNGFKVKNLGIKVDIGEFIQSIKESNATALGMSGLLVKSTQVMKENLETLQKEGIKIPVLLGGAALTRSFIDDFGPIFYCKDAFDGVTAMSR
IE-
>tr|Q0BVV3|Q0BVV3_GRABC 5-methyltetrahydrofolate--homocysteine methyltransferase OX=391165 OS=Granulibacter bethesdensis (strain ATCC BAA-1260 / CGDNIH1). GN= PE=3 SV=1
-PHLLDALRD-QVLLCDGGMGSRVQALDLDVENCTEILNLSRPDLVREIHRGYYEAGADMVETNSFGGSPVTLGEELRAREINRIAAELAREAADSHRYV
VGSIGP-GTKLPSLGNIDYDPLEAGLAEQCRGLIDGGVDAFLIETCQDTLQIKAAVNGAKKARDTPIFVQVTVETGTLLVGPDIAAAATVIHAMDVPLIG
LNCATGPQEMAEHVKWLAANWTGLISMQPNAGLPEL-VDGQTHYPLSPEEMASWVERYIEDGVNLIGGCCGTNVPHIRALDAMLRRRPPIKRNS--IWVP
SVASLYGQTSLRQENSYFSIGERCNANGSKKWREAQEQHDWDTCISMGREQVGEGSNALDICTAFVGRNEGLEMNEVIRRFTSSVNAPLVIDSTETPVIE
AALKLHGGKPIINSINFEEHAAEERMILARKFGAAVIALTIDEEGMAKTPERKLAIAERLVRFAEKHGLPQSDLLIDPLTFTIATGNEDGEWTLEGIRMI
REKFEIQIILGLSNISFGLNARAVLNSVFLDHAVRAGMTGAIVHVSKIRPLHQIVMEDLIFDRRTPLQRLLEMFADRKAA-----DAVKKTRA-ATVEGR
LKDRIVDGDRKGLTDELDEALKTH-APLDIINTILLDGMKVVGELFGAGKMQLPFVLQSAETMKAAVAYLEPMMERV-EGQQKGTIVLATVKGDVHDIGK
NLVDIILTNNGYRVVNLGIKVPLADMVAAVKEHRAHAIGMSGLLVKSTVIMRENLEEMSRQGVDVPVLLGGAALTRNYVEDDGRVAYARDAFDGLHLMDK
VT-
>tr|G7Z3X0|G7Z3X0_AZOL4 B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase OX=862719 OS=Azospirillum lipoferum (strain 4B). GN= PE=3 SV=1
-PHILDTLRD-RVLLCDGGFGSRIQALDLDVENCTDILPLSRPDIVRDIHRGYFEAGADMVETDTFGASPVTLGEGIKAFEINQRAVELAREAAESPRFV
IGSIGP-GTKLPSLGHIAYQPAEDSFYVQAAGLIAGGADAILVETCQDPLQIKAAVNGIKRARDTPVFVQVTVETGTLLVGTDIAAAATVIQALDVPLMG
LNCATGPLEMSEHVRWLSQNWPGLISVQPNAGLPEL-VDGKTHYPLLANDFAHWLERFVEDGVNLVGGCCGTNVPHIAAANQMLRKRPPKGRTV--HWVP
AVASLYSQVTLRQENAFFAIGERCNANGSKKWRELQEKNDWDGCVEMAREQVKEGSHSLDVCTAFVGRDEVAEMNAVISRFAGSVTAPLVIDSTEYKVLE
QALALYGGKAILNSINFEEEPARKRLELAKKFGAAVIALTIDEEGMAKTPDRKLAIAKRLYDLANEYGLAPSDLLFDPLTFTIATGNEDAIWTLEGIEAI
AREMGCQIILGLSNVSFGLNARHVLNSVFLDHAVKKGMTGAIVHVSKILPLHQITAEDLIFDRRAPLQAFIALFEGRKAA-----DAKKKARA-ENVEDR
LKERIVDGDRTGLEDDLAEAMKTH-PPLEIINTYLLDGMKVVGELFGAGKMQLPFVLQSAETMKAAVAWLEPHMEKI-EGQQKGTLVLATVKGDVHDIGK
NLVDIILTNNGYKVINLGIKQPVTAIIQAAKEHKADAVGMSGLLVKSTVVMRENLEEMTREGLEVPVLLGGAALTRAYVEGDGRVAYAGDAFDGLTLMDK
VV-
>tr|K9HHX9|K9HHX9_9PROT 5-methyltetrahydrofolate--homocysteine methyltransferase OX=1238182 OS=Caenispirillum salinarum AK4. GN=C882_1217 PE=4 SV=1
-TDFLDHLHD-RVLLCDGGMGSLVQAMSLSVENCTEILTRSRPDVVREIHTKYLEAGADVVQSNTFGGSTITLAEGLECFELNKRSVEIAREACEQRRFV
LGGIGP-GTKLPSLGHIDYDSLEAGFATQAKGLIAGGCDGILIETAQDPLQVKAAINGAKIARSMPILVQVTVETGTMLVGTDIAGAATIMEAMGVDSLG
LNCATGPQEMAEHVNWLKENWPRAITLQPNAGLPEL-RDGATFYPLTPRELADWHKRFVEDGVNMIGSCCGSNPDHTAAVDAMLKDRPVVKRSV--HWVP
GVASLYGRVDMRQENAFLSIGERCNANGSKKFRELQEAEDWDAIVGVGRDQVKEGSHTLDVCTAFVGRDEVRDMTNVVTRMRGGINAPLVFDSTETPVLE
AALKLYGGKAIINSINFEEQHAAERLALAKKFGAAVVALTIDEEGMAKTAEGKLAIAKRLYDFANKHGLPASDLMFDPLTFTICTGNEDGLETLDAIEMI
AKELEAQIILGLSNISFGLKGRHVLNSVFLDHAVKRGMTGAIVHVSKIMPLHKIAAEDLIFDRRAPLHAFIDKFKDRTVA-----AVEKT-RP-ETVEER
LKERIIDGDRKGLDEDLAEAMEKY-PPLEIINTLLLDGMKVVGELFGAGKMQLPFVLQSAETMKAAVAWLEPHMEKI-EGQEKGILVLATVKGDVHDIGK
NLVDIILTNNGYKVINLGIKQPVASIIAAAKEHKADAVGMSGLLVKSTVIMRENLEEMTREGLDIPVILGGAALTRNYVETDKRVAYARDAFDGLNLMAR
IA-
>tr|B6BGS7|B6BGS7_9HELI Methionine synthase (5-methyltetrahydrofolate--homocysteine methyltransferase) OX=929558 OS=Sulfurimonas gotlandica GD1. GN= PE=3 SV=1
-QYILDTIKK-RPLIIDGAMGTQLQQRDDKISGCNELLNVTAPEVLSEIFHAYLTAGADLITTNTFGSFSWVLDEQIRAYELTKAGAELVKQECEKPRFC
LGSVGP-GTKLPSLGHITYDEMHEGYTEFCLALIDGGVDIFLLETCQDPLQIKAALHACQEACEIPMMVSVTIESGTMLIGTDAATIATILEPFDILSLG
FNCGTGPEQVLKHVKTLSEVWHKPISVHANAGLPQN-RGGYTYYPMGPDEFTEQQEKFLFDGVSFLGGCCGTTPQHIRALVDKVN-SIPKAPSG--SHEN
SIASLFNTTTLMQEPAPLLMGERSNATGSKAFRELLLAEDYEGTLSVAQQQVRAGAHVIDVNVGFAGRDETKDMNAVMGMYNQKIALPLMPDSTQTTGLE
TALKNIGGKPILNSVNLEEPKFDEVCRLAKKFGTSLVCLTIDEVGMAKTVENKLAVADRIIDLANRHGIKKEDLIFDVLTFTLGSGDAEGINTIEAIRAL
RKKHEVSATLGLSNISFGLDARPYLNSMFLHHCIEAGLTSVIINVKHIIPINKIICDDLIFNRKPALFNFIEHFSTKAID-----NDVEDAAYLMSDEEK
IAKLLMDGDKERMIPLVEEARKTI-APEKIVNEILIDAMKVVGELFGSGQMQLPFVLQSAETMKKTVDHLNPYLPKV-EKTVDTTLALGTVKGDVHDVGK
NLVDIILSNNGFKVQNLGIKVELEDFVQATKDGHISAFGMSGLLVKSTQVMQENLKALKAEGIDIPVLLGGAALTRTFIDDFGPIFYCKDAFDGVTAMSR
IE-
>tr|E0US60|E0US60_SULAO Methionine synthase (B12-dependent) OX=563040 OS=/ OK10). GN= PE=3 SV=1
-QYILETIKK-RPLIIDGAMGTQLQQRDDKIPGCNELLNVTAPEIMNEIFHAYLNAGADFITTNTFGSFSWVLDENIRAYELTRAGAELVKKQCEAPRFC
LGSIGP-GTKLPSLGHITYDEMYAGYTEFCLALIDGGVDVFLIETAQDPLQIKAALHAIQEACEIPIMVSVTIESGTMLIGTDAETIATIMEPFDILSLG
FNCGTGPEQVLKHVKTLSELWGKPISVHANAGLPQN-RGGYTYYPMGPDEFVVQQEKFLYDGVSFLGGCCGTTPQHIRALVDKVT-AIPKIPSG--SQQN
SIASLFNTVPLMQQPAPLLVGERSNATGSKAFRELLLAENYEGTLSVAQQQVRAGAHVLDVNVGFAGRDETKDMTEVMAMYAQKIALPLMPDSTQTKGLE
TALKHIGGKPILNSVNLEEPKFDAVCQLAKKYGASLVCLTIDEKGMAKTVEDKIKVAERIIDLANRHGIKKEDLVFDVLTFTLGSGDEEGINTIEAIRQL
RQKHEVGAILGLSNISFGLDARPYLNSMFLHHCVEAGLTSVIINVKHIIPLNKIICDDLIFNRKPALFTFIEHFSSKAVD-----NNAVDEEYLMSNEEK
IAKLLMDGDKDRMIPLVEEARHKI-APQKIVNEILIDAMKVVGELFGSGQMQLPFVLQSAETMKKAVDHLNPYLPKV-EKETDTTLVLGTVKGDVHDVGK
NLVDIILSNNGYKVINLGIKVELDSFLETLEKSNAQALGMSGLLVKSTQVMLENLNILQEKGIKIPVLLGGAALTKAFIDDFGPIFYCKDAFDGVTAMSR
IE-
>tr|K5YN35|K5YN35_9PROT Methionine synthase OX=1214225 OS=Acidocella sp. MX-AZ02. GN=MXAZACID_06296 PE=4 SV=1
-PHLLEALSR-NVLLCDGGMGSRVQALTLDIENCTEVLNLSRPDLVREIHRGYFEAGSDMVQTNSFGGSPITLAEELRAFEINKIAGELAREAAESQRWV
VGSIGP-GTKLPSLGNIAYDPLEEALYAQCVGLLAGGVDALLIETCQDTLQIKAAVNGAKRAIDTPIFVQVTVETGTLLVGPDIAAAATVIHALDVPLMG
LNCATGPQEMAEHVRYLSQSWPGKISVQPNAGLPEL-VDGQTHYPLSGAEMASWVERFVEDGVNLIGGCCGTSIPHIQALDGMLRKRPPIARKF--HWVP
SVASLYGAVPLRQENAYFSIGERCNANGSKKWRELQESGDWDGCVAMGREQVAEASNALDICTAFVGRDEIAEMNQVITRFTSSVNAPLVIDSTETPVIE
AALKLHGGKPIINSINFEEGHARERLKLAKKFGAAMIALTIDEVGMAKEPADKLRIAERLVAFADQYGLPQSDLMIDPLTFTIATGNEDGQWTLEGIKLI
RDKFDIQIILGLSNISFGLNARAVLNSVFLDHAVKAGMTGAIVHVSKIRPLHLIVCEDLIFDRREPLQKLLEMFADRKAA-----DATKKKRA-ETPEGR
LKDRIVDGDRKGLTEDLDEALKTH-KPLEIINNILLDGMKVVGELFGAGKMQLPFVLQSAETMKAAVAYLEPMMERV-EGEERGIIVLATVKGDVHDIGK
NLVDIILTNNGYKVVNLGIKVPLAEMVAAAKEHKAHAIGMSGLLVKSTVVMRENLEEMSRQGLDIPVMLGGAALTRNYVEEDGRVAYARDAFDGLHLMDK
VT-
>tr|G2HRL1|G2HRL1_9PROT 5-methyltetrahydrofolate--homocysteine methyltransferase OX=944546 OS=Arcobacter butzleri ED-1. GN=ABED_0109 PE=3 SV=1
-ELIKNLIDK-RVLIIDGAMGTQLQIA--DIKGCNELLNLTAPHILETIHDNYAKAGADLISTNTFGSMPWVLDENIMSYELSKLGASLVKKSCEKPRFC
LASIGP-GTKLPSLGHIKYDEMYEGYKIMAKGLVDGGTDIFLLETCQDPLQIKAALHALNDVA-IPIMVSVTIESGTMLIGTDAMTIAAIMAPFNILSLG
FNCGTGPVQVHKHVKTLSQVCKFPISVHSNAGLPQN-RGGKTYYPMQPEEFTALQKEFLINGVSFLGGCCGTTPEHIEALAKAVE-NEPLKPCG--FLKA
SLASLFNIVPLKQEPAPLLIGERSNATGSKAFRELLKANDYEGTLSVAQQQVRAGAHVIDVSVGFAGRDERFDMDKVVSLYSQKIALPLMPDSTQILALE
AALKQIGGRCIINSVNLEIEKFDAVCSLAKKFGAALVCLVIDEIGMAKSKERKLEVAERIFDLCNRHGFDPADLVFDMLTFTIGSGDDEGIETLEAIREF
EIRHEVGTTLGLSNISFGLAARIYLNSIYLDHCVKAGLTSAIVNVKHILPLNKIACDNLIFNIWEPLFAFIEHFSNVEGQ-----EEQSDEEYQLEPIEK
VKKLLLDGDKERLIPLALELRHTI-SPEIIVNEWLIDGMKVIGELFGSGQMQLPFVLQSAETMKACVDSLNPYLPKQ-EKASETTLILGTVKGDVHDVGK
NLVDIILSNNGFKVVNVGIKADLGQFVEELNKHNAHAIGMSGLLVKSTAVMKENLEELQKLGIKVPVLLGGAALTKNFVDEYGPIFYCRDAFDGVVSMQR
IE-
>tr|A4U3E9|A4U3E9_9PROT Methionine synthase OX=55518 OS=Magnetospirillum gryphiswaldense. GN= PE=3 SV=1
-TNILDHLHQ-RVLLCDGGTGALVQAMNLSVDNCTDILVESRPDVVRNIAMQYFNAGADMVETNTFGASPITLAEGIKAFDLNKRAAEIAREAAEEARFV
LGSVGP-GTKLPSLGHIGYDELEAAYVVQCAGQIAGGADAILIETCQDPLQIKAAVNGAKIARDTPIFVQVTVETGTMLVGADIAAAATVVHSLGVPSLG
LNCAAGPQEMLEHVKYLVENWPDLISLQPNAGLPEL-VDGQTRYPLLPEELAVWHERFVGMGVNLLGGCCGTTPAHIGATHQMLQRRPPVKRSV--HWVP
AVASLYSQVTLRQENAFLAIGERCNANGSKKFRDLQDAEDWDGIVAMAREQVKEGSHTLDVCTAFVGRKEVADMTQVVTRLRGAVTTPLVIDSTELPVLE
AALKLYGGKAILNSINFEEEDAADRLKLAKKFGAAVVALTIDEEGMAKDCAAKLRIAHRLYDFANQHGLPAGDLLFDPLTFTICTGNEDGLETLDAIEAL
ARELECGIVLGLSNISFGLKARQVLNSVFNDYAVKRGMTGAIVHVSKILPLHSIAAEDLIFDRRSPLQAFIALFGDRKAA-----ENKKE-LP-AKIEDR
LKQRIVDGDRTGLDDDLAAAMAEW-APLAIINDLLLDGMKVVGELFGSGKMQLPFVLQSAETMKAAVAYLEPHMEKS-DGSAKATMVLATVKGDVHDIGK
NLVDIILTNNGYKVVNIGIKQPVGEIIKAAKEHKADAVGMSGLLVKSTVIMKDNLEEMRAQGLDVPVLLGGAALTRKFVEEDSGVAYARDAFDGLDLMAK
VA-
>tr|D5V4W3|D5V4W3_ARCNC Methionine synthase OX=572480 OS=NCTC 12251 / CI) (Campylobacter nitrofigilis). GN= PE=3 SV=1
-NRINEIIQN-KVLIIDGAMGTQLQNA--EIKGCNELLNETAPEILEGIHDAYAKAGANLISTNTFGTMPWVLDEGIKAYELSKLGAELVKKSCKKPRFC
LGSIGP-GTKLPSLGHIRYDEMYEGYKEVANGLADGGCDIYLLETCQDPLQIKAALHALTDTH-IPVMVSVTIESGTMLIGTDAMTIAAIMSPFNILSLG
FNCGTGPKQVHKHVKTLSEVCKFPISVHANAGLPQN-KGGVSYYPMGPEEFTQLQSSFLINGVSFLGGCCGTTPEHIEALANKVR-GIPKAPSG--FLKA
SLASLFNTVPLKQDPAPLLIGERSNATGSKAFRDLLKDNNYEGTLSVGQQQVRAGAHIIDVSVGFAGRDETGDMDKVVELYSQKVSLPLMPDSTQIKALE
AALKQIGGRCIINSVNLEEEKFDAVCKLAKKFGAALVCLVIDEVGMAKTKEDKIRIAERIYDLCNRHGFNPEDLVFDMLTFTIGSGDDEGVETMEAIREF
QILHEVGTTLGLSNISFGLDARVYLNSIYLDHCVKAGLTSAIVNVKHILPLNKIACDDLIFNNQEPLFKFIDHFSNVEAQ-----EDQSDEEYLMEPIDK
VKKLLLDGDKDRLLPLVDELRHTI-KAEMIVNEWLIDGMKIIGELFGSGQMQLPFVLQSAETMKATVDALNPYLPKE-EKASETVLVIGTVKGDVHDVGK
NLVDIILSNNGFKVINIGIKADINDFIIAVQKHKAQAIGMSGLLVKSTAVMKENLEELKRQGIDIPVLLGGAALTKSFVNEYGPIFYCRDAFDGVVSMQR
IE-
>tr|D1B335|D1B335_SULD5 Methionine synthase OX=525898 OS=Sulfurospirillum deleyianum (strain ATCC 51133 / DSM 6946 / 5175). GN= PE=3 SV=1
-ATLQELISE-KILIIDGAMGTQIQAL--QIPGCNELLNVTCKDEISKIHRGYLLAGADIIKTNTFGALPWVLDDGIRTYELARTGVEIVKEACLAPRFC
AAAFGP-GTKLPSLGHIGYDEMYAGYRVAATGAIEGGCDVFLIETAQDPLQIKAALHAIFDAQKLPVMVSVTIESGTMLIGTDATTIATILEPFDIMSLG
FNCGTGPEQVEKHVKTLSSVWSKPISVHANAGLPQN-RGGYTFYPMGPREFAELQEKFTIAGVAILGGCCGTTPQHILELSKRVE-GKLLAPQG--EMAR
SIASLFEVRALKQDPAPFLIGERSNATGSKAFRELLLAEDYDGTLSVAQQQVRSGAHGIDVSVGFAGRDEIKDTTAVVGRYVQKILLPLMPDTTQVPALE
CALKLIGSKPIINSVNLEIEKFDKVCSLAKRFGCALVCLTIDEQGMAKTKAQKVAIAERIFQLATKHGINAGDLVFDLLTFTVGSGDAEAIETIEAIREF
HAMHEVGFVLGISNISFGLAAREYLNSVFLHHCVEAGLSMAIVNVKNTLPMHKIVCEDLLFNRREPLFKFISHFEGVVEN-----KDESDAAYLMSTKEK
IATLLIDGDKERMLALLPTAKEEI-AAEVIVNEILIDAMKVVGELFGSGKMQLPFVLQSAEVMKASVDYLQPYLPKT-EKSTTTTLIIGTVKGDVHDVGK
NLVDIILSNNGFKVVNIGIKADLEQFLEALKEHKADAIGMSGLLVKSTNVMKENLEAMQKMGLNIPVILGGAALTDNFVEDFGPIFYCKDAFEGITAMSR
IE-
>tr|H8FSY8|H8FSY8_RHOMO Methionine synthase OX=1150626 OS=Phaeospirillum molischianum DSM 120. GN= PE=3 SV=1
-SSILDHLSQ-AVLLCDGGTGALVQAMNLSVDNCTEILVESRPDVIRGIHARYFSAGADMVEANTFGASPITLAEGIRAFDLNKRAIELAHEAAEQRRYV
LGAIGP-GTKLPSLGHIGYDPLEAAYLIQARGMIAGNVDAFLIETCQDPLQIKAAVNGCKRALTAPIFVQVTVETGTLLVGADIAAAATVIQSLGVPLIG
MNCAAGPQEMAEHFKWLVDNWPGFLSIQPNAGLPEL-IDGRTHYPLLPDELAVWHERFVGMGANLVGGCCGTTPDHIGATDAMLRRRPPVKRLV--HWVP
SVASLYTQVPLRQENAFLSIGERCNANGSKKFRDLQDAEDWDGITATAREQVKEGSHTLDVCTAFVGRDEIRDMTEVVSRLRGAVTTPLVIDSTELPVLE
AGLKLYGGKAILNSINFEEEDAAARLKLARTFGSAVVALTIDEAGMAKDAESKLRIARRLYDFANQHGLPASDLLFDPLTFTICTGVIDAIETLDAIERI
AAEMDCGIILGLSNVSFGLKARQVLNSVFIDLAIKRGMTGAIVHVSKILPLHTLAAEDLILDRDPALSRFIALFGDRTVA-----EVKKE-RA-ATPEER
LKQRIIDGDRTGLDDDLLAAIEAW-QPLDIINQLLLDGMKVVGELFGSGKMQLPFVLQSAETMKAAVAFLEPRMEKA-DGQQKATIVLATVKGDVHDIGK
NLVDIILTNNGYRVVNLGIKQPVAEIIKAAREHKADAVGMSGLLVKSTVIMRENLEEMSREGLDLPVLLGGAALTRKYVEEAGRVAYARDAFDGLNLMAK
VV-
>tr|C3XLV5|C3XLV5_9HELI S-methyltransferase OX=556267 OS=Helicobacter winghamensis ATCC BAA-430. GN=HWAG_00786 PE=3 SV=1
-MVLRNCIKE-RVLILDGAMGTEIQKH--NIQGCSEALNLYAKDIIKAIHTSYLQAGANILKTNTFGVMPWVLAEGLHCKEIAKTGVELAKECIKKALFV
AASLGP-GTKLPSLGHITYDSMEEGYALCVEGFKEADADVILLETAQDPLQIKAALNAIKNTA-IPIMVSVTIETGTMLIGTDITTLFHILEPYDLLSLG
INCGLGPDLAHKHLVTLSEVCKFPISIHTNAGLPEN-RGGVTYYPMDAEEFSTIEKSFLIPGVAFLGGCCGTTPEHIRQLVQKTQ-SIPKAPKC--TYQP
SITSLFEAKELKQFPAPLLIGERSNATGSKAFRELLLNEDYEGALSVGSAQVRSGAHCLDLSVAFAGRDESKDMQELITRYATKITLPLMPDSTQVNALE
IALKHIGGRAIINSANLEITKFDKVASLAKKFGAALICLTIDEEGMCKTFERKIACAKRMMERATIHNLREEDIIFDPLTFTIGSGDAEGMQTLNTIKEL
SKLYKAGTTLGLSNISFGLSGRICLNSIFLHHAIKNGLTSAIVNVSHIIPYNKLVCENLIFNTELPLYAFIKHFESKNTL-----DLPKQEQDVLSIEER
IQKYLIDGELNAMLELLPSAKDSI-SPEKIINEILIDAMKIVGERFGNGEMQLPFVLQSAEVMKKSVDYLNAFLPKK-QSTHKTTIVLGTVKGDVHDVGK
NLVDIILTNNGFSVINIGIKAELEKFLEVLQTQKVDCIGMSGLLVKSTLVMKENLEALKKLDIKIPIMLGGAALNRNFVEEYGVIFYCKDAFDSVAAMQI
IQ-
>tr|Q1DAW7|Q1DAW7_MYXXD 5-methyltetrahydrofolate--homocysteine methyltransferase OX=246197 OS=Myxococcus xanthus (strain DK 1622). GN= PE=3 SV=1
-EALRAAMRE-RVLVLDGAMGTLLQNEDLKAAGCNEHLVLTRPELVESIHARYFAAGADVTETDSFGGTPLVLAEGLKALEINEVSARLARNAAAAMRWV
AGSIGPTTKAISVTGGVTFEELVDNFAVQAEGLALGGSDYLLIETAQDTRNVKAALLGAERAFALPVAVSGTIEMGTMLAGQSVESLAASLEHTDLLYLG
LNCATGPDFMTDHLRSLASMSAFPVACVPNAGLP----DENGNYLETPEMLARSVRRFCQGWLNVVGGCCGTHAGHIETMAKAVQGLKPRAGSP--RPRA
SL-SGVDYLEVTDEQRPLIVGERTNVIGSKKFKELIVAGQFDDASEIARAQVKRGAQVIDICLANPDRDELEDMRNFLEAVIKKVRVPLMIDSTDERVIE
MALTYSQGKAIINSVNLEEERFEKVVPLARRFGAALVVGCIDEVGMAVTRQRKLEVAERSYELLKKYGMKPEDLYFDPLVFPCATGDAQGVETIEGVRLI
KQRFRSKTVLGISNVSFGLPGREVLNSVFLYHNVQAGLDMALVNSEKLERYPSLLSEDLLYNRGAPVTPFAAAFRERKAA-----RVQVSTLP---LEER
LQRYIIEGTRDGLTADLEAAMQKY-TPLEIINGPLMKGMDEVGRLFGANELIVAEVLQSAESMKAAVSFLEPHMSKA-QAAMRGKVVLATVKGDVHDIGK
NLVEIILANNGFHIVNLGIKVPPEQLVLAVREHQPDILGLSGLLVKSAHQMVATAEDLKRAGVDVPILVGGAALSRNFVDRNATVAYAQDAMNGLELAKQ
IV-
>tr|Q2IM33|Q2IM33_ANADE Methionine synthase (B12-dependent) OX=290397 OS=Anaeromyxobacter dehalogenans (strain 2CP-C). GN= PE=3 SV=1
-MTFREALER-RPLVFDGAMGTQIQRHQLTAAGANDLLTLTRPDLIEEIHARYFAVGCDVVETNTFGSSRLKLDEGLRTYEVNCRAAILARRAAERPRFV
AGSIGPTSSSDPALGNITSDALERIFFEQAKGLVEGGVDALIIETQQDMLELRAAVLACDAVRVFVIAQPTLIDNGRMLLGTDVGSAVATLERLPVDAVG
LNCSTGPDEMRASVKALAERCSHWVSVLPNAGMPEN-EDGRAVYKLSPDDLARALAGFVEYGVDIVGGCCGTTPEHLRKVVEALRGLSPRRRRP--APAA
ELSSAMKAVPLAMEPRPLVVGERLNSQGSRKVKELLLADDYAGLVQIARGQVEAGAHVLDVCVALNERDEAAQMRTLAKLLAQSVDAPLMIDSTEPDVIE
GALKVYPGRCIVNSVNLEGERVRRVLPLVRRYGAAVVAMTIDEKGMAQTAERKAEVARRIVAV-KDHGIPPDSLVFDALTFTLATGGEEAVETLEGIRRI
KAENGVLTTLGVSNVSFGLAAREVVNSVFLYHAVQAGLDLAIVNPKDILPYPAILAEDLVFDRRPALARLIAHFGAKAPE-----KAAVDPLAGKGAEER
IHLQILHRRPEGIEALIDEALTRR-SAVDVLNQVLLPAMKDVGDRFGAGELILPFVLQSAEVMKKAVAHLEQFLEKK-AGATKGNVVLATVYGDVHDIGK
NLVKTILSNNGFTVHDLGKQVPVTTVLDKALQVNADAIGLSALLVSTSKQMPFCVEELHRRNLSFPVIIGGAAINRRFGYRTGGVFYAKDAFEGLEVVEA
LV-
>tr|A6Q2F4|A6Q2F4_NITSB 5-methyltetrahydrofolate--homocysteine methyltransferase OX=387092 OS=Nitratiruptor sp. (strain SB155-2). GN= PE=3 SV=1
--MIKRLLRE-RILIIDGAMGTQLQAKANEISGCNELLNRTAPKVIKSIHEAYAKVGADIIKTNTFGSMPWVLDEDLEAYDLTKRGCELVKEVCETPRFV
ACSLGP-GTKLPSLGHIDYDAMYVGYSEAARGAKDGGADIFLLETCQDPLQIKAAMHACQDTAEIPIMVSVTIENGTMLIGTDAATIATILEPFDIISLG
FNCGTGPDMVEKHVRVLSEVWDRPISVHANAGLPQN-RGGYTYYPMGPKEFTELEAKFTIDGVALLGGCCGTTPQHIKALVDAVE-GKPLPPKG--KQPR
SIASLFESRTLMQDPAPFLMGERSNATGSKAFRELLLKSDYEGTLSVAQQQVRSGAHGIDVSVGFAGRDETKDMHEVIKLYNEKISIPLMPDSTQVPAIE
VALKHIGGRPIINSANLEVEKFDKICSLAKRYGAALVLLAIDEEGMAKTKEKKLAVAERMYERANKHGLNPGDLVFDLLTFTVGSGDEEAIETIEAIREL
RRRHEVGAVLGVSNISFGLDAREYLNSVFLHHCVEAGLTMAIVNVKNLIPYHKIVCEDLLFNRREPLFAFIEHFSKADKK-----EAASDDELSLPLEEQ
IHKLLIDGDKERMMPLLEKAKDEI-DPEKIINEILIGAMKEVGDLFGSGQMQLPFVLQSAEVMKAAVDYLNQFLPKT-DKQSQTTLILGTVKGDVHDVGK
NLVDILLTNNGFKVINLGIKVELEEFIKAYKEHNAQAIGMSGLLVKSTQVMLENLKEMKQKGIDAPILLGGAALTKKFVDEFGPIFYCRDAFDGIVAMSR
IE-
>tr|C5EY17|C5EY17_9HELI S-methyltransferase OX=537972 OS=Helicobacter pullorum MIT 98-5489. GN=HPMG_00244 PE=3 SV=1
---MQELIQK-QVLILDGAMGTEIQKR--ENIGCTEALNLYSPQIIYEIYTSYLQAGANIITSNTFGAMEWVLAEEMHSKEIAKLGVQLAKEAILKALFV
AGSLGP-GTKLPSLGHIDYDTMFLGYCKVVSGFKEANVDLILLETAQDPLQIKAALHAIREID-IPIMVSATIENGSMLIGTDIATLFYILEPFDIFSLG
INCGLGPDLAKKYLLELSQVSKFPISIHANAGLPQN-KGGVTYYPMEAEEFSEIESEFLISGVALLGGCCGTTPKHIQKLVEKTK-DKPSLPKG--EYKP
SIASLFGAYELKQNPAPLLIGERSNATGSKAFRELLLNENYEGALGVGSEQVKKGAHVLDVSVAFAGRDESKDMQELISLYATKIPLPLMPDSTQVIALE
IALKLIGGRCIINSANLEIEKFDKIAGLAKKFGCVLVCLTIDEKGMCKTKERKVECAKRMMQRAEVHHLREEDIIFDPLTFTIGSGDEEGMETLGAIEEI
MKIYKAGSTLGLSNISFGLSGRICLNSVFLYHAIQKGLTSAIVNVAHIIPYARLVCEDLIFNTQKPLYDFISYFEKKSGL-----DLDSKEDESLSTQER
ISKYLIEGDLNAMQKILPVAKDEI-NPEVIVNEILIDAMKVVGERFGAGEMQLPFVLQSAEVMKKSVDYLNEFLPKK-TNSHKTTIVIGTVKGDVHDVGK
NLVDIILSNNGFNVINIGIKAELEKFLEVLKKEKVDCIGMSGLLVKSTLVMKENLEELKRLGIKIPIMLGGAALNRNFVDEYGVIFYCKDAFDSVAAMQI
IQ-
>tr|Q7M929|Q7M929_WOLSU S-METHYLTRANSFERASE OX=273121 OS=11488 / FDC 602W) (Vibrio succinogenes). GN= PE=3 SV=1
-MKMEQFFRQ-RVMILDGAMGTEIQKF--DLKGCSEILNVTRGDVILSIHRSYLEAGADILKSNTFGALPWVLEEGIRAYEMAFAGAQIAKEACDSPRFV
AGSLGP-GTKLPSLGHIDYDTMFEGYKEAARGLKEGGADLFLLETCQDPLQIKAAVHACKEVD-MPIMVSATIETGTMLIGTDIKTLAVILEPLEIFSLG
INCGLGPDMAEKHLKALAQYAPFPLSIHANAGLPQN-VGGCTFYPMEPKEFAEIEEEFLIEGVAFLGGCCGTTPEHIRQLKERVG-ISPTPPAK--RTPV
ALASLFESVELKQSPAPLLIGERSNATGSKAFRELLVAEDYEGALGVGLAQVKSGAHVLDVSVGFAGRDERRDMREVVSRYATNLPLPLMPDSTQSEVLE
VALKCIGGRPIINSANLEIEKFDRVCALAKRFGAVLICLTIDEEGMAKTKERKVACAKRMMERASVHGLRERDIIFDTLTFTIGSGDEEGIETLDAIQEL
SQLYEAGTTLGLSNISFGLSARIYLNSIFLYHAVQRGLTSAIVNVSHLLPYAKVSCEALIFNQTQPLYAFIDHFSDKKA------ELASDSTLEMDTQEK
IAHLLIQGDKEGMKALLPSAKEEI-AAERIINEILIEAMKVVGERFGKGEMQLPFVLQSAEVMKMSVDYLNAYLPKT-EKKNQTTMILGTVKGDVHDVGK
NLVDIILTNNGYKIVNIGIKADIEQFIQAYHEHKADAIGMSGLLVKSTLVMKENLEELARRGIHCPVILGGAALNRAFVDDYGIIFYCKDAFDGMAAMEK
IE-
>tr|F2JJA7|F2JJA7_CELLD Methionine synthase OX=642492 OS=11756 / RHM5) (Clostridium lentocellum). GN= PE=3 SV=1
--ELISILKQ-RILVLDGAMGTSIQGYQLTEE--NDLLSLTKPEVIKKIHRSFLKAGADMIETNTFNATVISQADDLLIYELNYESARIAREVADEPRFV
AGAIGPTNKTASLS-NISFDELVSAYSEQIAGLIAGGVDCLLIETIFDTLNARAAIVAAQEVMTLPIMISGTLDSGRTLSGQKLEAFAQSVRNEHVISIG
LNCSFGGADLMPFIKELSKTQNLYVSVYPNAGLPNV--LG--AYDEAPYMTAQYIEALAKGQVNIVGG-CGTTPEHIAAIAKCV-GV-PRTIPT--L-KE
SIYCGLETVKSHKANNFINIGERTNVAGSAKFARLIRERNYEEALLIAKEQVENGAQIIDVNFDDGLLNSEEEMAYFLKLIA-IASKPIMIDSSKWSVIE
AGLKSIQGKPIVNSISLKEEEFLEHAKVVKAFGAAVVVMAFDERGQADTFERKIEICERAYRLLDTLHFPPEDIIFDPNILAIATGMEEAAYYIEATRWI
KEHLYAKVSGGVSNLSFSF-NREAMHSVFLYHAIEAGMDMGIV----IQIYDDILVEDVIFK--ERLLEQAENYKQ---KV-----TIQQNE--WQLDDR
LSYALVKGTTEFIEDDLAEAVTVYPKALHIIEGPLMAGMTKVGDLFGEGK--LPQV-KSARVMKKAVGFLLPYME---ASHKAGKILIATVKGDVHDIGK
NIVGVVLACNNFEIIDLGVMTPCETILDTAIKEKVDIIGLSGLITPSLDEMAHVAEEMERRGMTIPLIIGGATTSKLHTA-----VYGY-A----EI---
-L-
>tr|D9SSS9|D9SSS9_CLOC7 Methionine synthase OX=573061 OS=743B). GN= PE=3 SV=1
--SIEKYLQE-KILVLDGAMGTAIQGFGLVEE--NDILNITNPDIVKKVHQMYLDAEADIIETNTFNANRISQGDGLKIYELNFKGAQIAKAIAEEPRFV
AGSMGPTNRAASMS-NITFDKLVEAYKEQAEGLIDGGCDLLLIETIIDALNARAAIFAVNTVLKLPIMISGTIDSGRLLSGQTLKAFYETVRNENLLSIG
LNCAFGAEDMIPFIREAAKTQNKYISFYPNAGLPNA--LG--QYDELPEKTASFIEILAKEGLNIVGG-CGTTPAHIAAIAKTV-NY-PRIVPE--I-RE
TIYCGLEEVKVNSQSNFVNIGERTNVAGSAKFARLIREKQYEEAIDIAKNQVENGAQIIDINFDDGLLDAKEEMDKFLKLVA-IAKVPVMIDSSKWEVLE
TGLKAIQGKAIVNSISLKEEEFIKEATYINKFNAGVVVMAFDEKGQADTYERKIEICKRAYDILNKVNFPPENIIFDPNILAIATGIEEGVDYINAVRWI
KENLYAKVSGGVSNLSFSF-NREAIHSVFLYHAIKAGMDMGIV----IQIYDEIRVEDVVLK--ERLLEFAQSYNN---SS-----SENKLK--WPVEER
LKYSLVKGITEYLEEDLEEVRKNYDKSLQVIEGPLMAGMSAVGELFGEGK--LPQV-KTARVMKKAVSILLPYIE---ENSKAGTVVFATVKGDVHDIGK
NIVGIVLGCNNFEVIDLGVMVPCETILQVAKEKKADIIALSGLITPSLEEMCNVAREMEAQGFDIPLMIGGATTSRTHTA-----VYTS-A----EA---
-V-
>tr|L7EI29|L7EI29_CLOPA B12-dependent methionine synthase OX=1262449 OS=Clostridium pasteurianum DSM 525. GN= PE=4 SV=1
--SIKDLLDK-KIVILDGAMGTCIQSFRLEEE--NDILNITKPEIIKEIHRQYFEAGADVVETNTFNGTSISQSDGMKIYEINFNGARLAREVADDPRFV
AGSVGPTNRTASLS-NVTFDELSKAYGDQIEGLIDGGVDFIIIETIFDALNARTAIFAAKNAIKLPIMISGTIDSGRILSGQTLEAFAETMRDEDVLIIG
LNCSFGAKDLIPFIRQLSKTQNKYISFYPNAGLPNS--MG--EYDEHPDDTAAFVKEIAREGINIVGG-CGTTPDHIKAISKAV-DV-PRRIPE--L-ME
TVFCGLEALKINKSNNFVNVGERTNVAGSAKFARLIREKKYEEALTVAKNQVENGAQIIDVNFDDALLDAKTEMDTFLKLVA-ISRVPIMIDSSKFEVLE
AGLKAIQGKAIVNSISLKEEEFIRQAQLIKKYGAGAVVMAFDEKGQADTYERRISICKRAYDILNKVGFLPCNVIFDPNILAIATGIEEAVDYINTTKWI
KENLYAKVSGGVSNLSFSF-NREAMHSVFLYHAIKAGMDMGIV----IQIYDEIKVEAVVLK--EELVEFAENYKA---KE-----NDNKHS--WDCKER
LTHALVKGIVEYIDEDVEECRVQHHRALEVIEGPLMDGMKTVGKLFGEGK--LPQV-KSARVMKKAVSFLLPYIE---GSTSAGKVVFATVKGDVHDIGK
NIVSVVLSCNNFEVVDLGVMVPAETILETAKKEKADIIALSGLITPSLEEMANVAEEMEQQGFKIPLMVGGATTSKTHTA-----VHTT-A----EA---
-V-
>tr|J7ITW4|J7ITW4_DESMD Methionine synthase (B12-dependent) OX=768704 OS=13706 / S10). GN= PE=3 SV=1
--NIEAYLKE-RILVLDGAMGTCIQGYDLNEQ--NDLLNISHPEIIEAIHKRYLEAGADIIETNTFNATRISQKDGMKVYELNLQGAKLAREAADLPRFV
AGSVGPTNRTASLS-NISFDELVLAYGEQIQGLVEGGVDLIMIETIFDSLNARAAIFAAEDVLTLPIIISGTVDSGRILSGQTLEAFVYTMKGEEILGIG
LNCSFGARDLIPFIKYLSKTQDRYVTFHPNAGLPNS--LG--EYEERPEETAALVKELAEQGLNIVGA-CGSTPAHIKAIAEAV-GI-PRKIPQ--L-KE
TVYCGLEAIVIKNENNFVNIGERTNVSGSAKFARLIREKNYEAALFVAKEQVENGAQIIDINFDDGLLDAVNEMDIFLKLLA-IARVPVMIDSSKFEVLE
VGLKAIQGKAVVNSISLKEAEFLRQATLIKRYGAGVVVMAFDEQGQADTFERRIAVCQRAYELLTKVKFPPTDIIFDPNILAIATGIEEAVDFINTVKWI
KANLYAKVSGGVSNLSFSF-NREAMHSVFLYHAIAAGMDMAIV----IQIYDEIKVEAVVLK--EKLLEFAENYQA---DQ-----VENKLA--WGPKER
LIQALVKGIAEFIEEDVEEVRGQYARAEMVIEGPLMDGMKVVGELFGDGK--LPQV-KSARVMKKAVSLLLPYIE---ESSSAGKVVAATVKGDVHDIGK
NIVSVILSCNNFEVIDLGVMASCEVILQAAKREKADIIALSGLITPSLDEMSNVAEEMERQGFNIPLMIGGATTSKTHTA-----VYSV-A----EV---
-V-
>tr|A6LY07|A6LY07_CLOB8 Methionine synthase OX=290402 OS=acetobutylicum). GN= PE=3 SV=1
--QIKELLEK-RILVLDGAMGTCIQNYKLEEK--NDILNLTNPNIIREIHEAYLESGADIIETNTFNSTSISQKDEMKIYELNFEGAKLAKEAADKPRFV
AGSLGPTNKTASLS-NISFDELAEAYKEQVLGLIDGGVDLILIETIFDALNARAALMGAKQGKDLPVIISGTIDSGRILSGQTLEAFANTMVDESIIAIG
LNCSFGAKDLIPFVKYLSRTQNRYISVYPNAGLPNS--FG--EYDEKPEETAALIKSLAEDGLNIVGG-CGTTPDHIKAVSEAI-DI-PRKIPD--I-TE
TVYCGLEALRANKENNFINIGERTNVAGSAKFARLIREKNYEEALSIAKDQVENGAQIVDINFDDALLDAKEEMDKFLKLLA-ISKVPVMIDSSKFEVLV
TGLKAIQGKPIVNSISLKEEEFKRQASIIRDFGAAVVVMAFDENGQADSYEKKISICKRAYDILNEVNFPPQNIVFDPNILTIATGIEEAVDFINATKWI
KENLYAKVSGGVSNLSFAF-NREAMHSVFLYHAIKNGMDMGIV----IQIYDEIKVEAVIFK--DELLEFAANFNK---KL-----EENKEA--WNVKER
LKTALVKGIDKYIKEDVEEVRAEYSKSLEVIEGPLMDGMNEVGKLFGDGK--LPQV-KSARVMKKAVEVLRPYLE---GSISAGKVVFATVKGDVHDIGK
NIVSVVLSCNNFEVIDLGVMVPTEIILETAKKENADIIALSGLITPSLEEMSNVAEEMEKQGFKIPLMVGGATTSKAHTA-----IHTT-A----EA---
-L-
>tr|G2FWJ8|G2FWJ8_9FIRM Methionine synthase OX=913865 OS=Desulfosporosinus sp. OT. GN= PE=3 SV=1
--TIENCLKE-RILVLDGAMGTCIQGYNLSEQ--NDLLNITHPEIIRAIHKTYLEAGADIIETNTFNANKISQKDGMKVYELNLQGAKLAREQADIPRFV
AGSVGPTNRTASLS-NISFDELVLAYEEQIQGLVDGRVDVLFIETIFDALNARAAVFAAGNVVTLPIFISGTIDSGRILSGQTLEAFAHTMKGDEIIGIG
LNCSFGAKDLIPFIKYLSKSQDRYVTFHPNAGLPNS--LG--VYEERPEETAALVKELAEEGLNIVGA-CGSTPAHIKAISEAV-GI-PRQIPA--L-TE
TVYCGLEAFKVKKENNFVNIGERTNVSGSAKFARLIREKNYEEALFIAKEQVENGAQIIDLNFDDALLDAHSEMDTFLKLLA-ISRVPVMIDSSKFEVLE
AGLKAIQGKAVVNSISLKEEEFIRQATLIKRYGAGIVVMAFDEQGQADTFDKRITVCKRAYDLLKTVKFPPTDIIFDPNILAIATGIEEAVDFINTVTWI
KRNLFVKVSGGVSNLSFSF-NREAMHSVFLYHAIAAGMDMAIV----IQIYDEIRVEDVVLK--EKLLDFAELYKA---DQ-----AENKLV--WDCKER
LIHALVKGIAEYIEEDVEEVRRQYDKAEKVIEGPLMDGMKVVGELFGEGK--LPQV-KSARVMKKAVGCLLPYIE---GSSSAGKVVMATVKGDVHDIGK
NIVAVILACNNFEVIDLGVMASCEVILQTAKKENADIIALSGLITPSLDEMSHVAEEMERQGFDIPLMIGGATTSKTHTA-----VYSV-A----EV---
-V-
>tr|I4D7D5|I4D7D5_9FIRM Methionine synthase (B12-dependent) OX=646529 OS=Desulfosporosinus acidiphilus SJ4. GN=Desaci_2784 PE=3 SV=1
--NIENYLKE-RILVLDGAMGTCIQGYDLAEQ--NDLLNLTHPEIVKEIHKRYLEAGADIIETNTFNATRISQKDGMKVYELNFQGAKLAREQADIPRFI
AGSVGPTNRTASLS-NISFDELVFAYEEQVKGLVDGGADIILVETIFDTLNAKAAVFAAQDVVTLPIFISGTIDSGRILSGQTLEAFAQTMKGDGILGIG
LNCSFGAKDLIPFIKYLSKSQDRYITFYPNAGLPNS--LG--EYEERPEETASLVKKLAAEGLNVVGA-CGSTPAHIKAISEAV-GI-PRKIPL--L-KE
TIFCGLEAIAIKKENNFVNIGERTNVSGSAKFARLIREKNYEEAILIAKEQVENGAQIIDINFDDGLLDAAREMDIFLKLLA-ISRVPVMIDSSKFEVIE
TGLKAMQGKAIVNSISLKEEEFIHQAALIKKYGAGVVVMAFDEQGQADTFDKRIAVCQRAYDLLNNVKFPPEDIIFDPNILAIGTGIEEAVDFIKAVKWI
KDNLHVKVSGGVSNLSFSF-NREAMHSVFLYHVIAAGMDMAIV----IQIYDEIKVEAVVLK--ENLIAFAESYKV---DQ-----VENKSA--WSPKNR
LVHALVKGISEFIEEDVEEVRRQYARAVEVIEGPLMEGMNVVGELFGEGK--LPQV-KSARVMKKAVSFLLPFIE---ESSSAGKVVMATVKGDVHDIGK
NIVSVILACNNFEVIDLGVMASSELILQTAKYEKADIIALSGLITPSLDEMTNVAEEMEGQGFTIPLMIGGATTSKTHTA-----VYSV-A----EI---
-T-
>tr|F7ZSI8|F7ZSI8_CLOAT B12-dependent methionine synthase OX=991791 OS=Clostridium acetobutylicum DSM 1731. GN= PE=3 SV=1
--SLKNLLNN-KILVLDGAMGTCIQSFNLDEG--NDVLNLTKPEIIKEIHKRYLEAGADIIETNTFNATEISQKDNMKIYDINFKGAKLAKEACTYPRFA
AGSIGPTNRTASLS-NVTFDELCNAYKHQIEALIDGGVDLLLIETIFDTLNARAAIFAAETVIKLPIIISGTIDSGRILSGQTLDAFAESLKNENIIAIG
LNCSFGAEELIPFIKRLSETQNRYISFHPNAGLPNS--LG--EYEELPEETASIVKKLALEGLNIVGG-CGTTPEHIRAISSVV-GI-PRKVPN--L-PK
TIYSGLENIKIDKNSNFINIGERTNVAGSRKFARLIREKNYEEALTIARHQVENGAQIIDINFDDALLDARSEMETFLRLIA-ISKVPVMIDSSNFEVLK
VGLKSIQGKAIVNSISLKEEKFIEEAKFIKNFGAGVVVMAFDEEGQAATYERKIEICKRAYTILEKVEFPPENIIFDPNILSIATGIEEAVNYIKAVKWI
KENLYAKVSGGVSNLSFSF-DRRAMHSVFLYHAINAGMDMGIV----IDLYDDIKVENVVLK--ESLLEFAQTYKK---TL-----EKHEDE--WSPSER
LSYALVKGNVEFIEEDIEEARKEYTNALEIIEVPLMNGMKKVGKLFGEGK--LPQV-KSARVMKKAVECLLPYIN---HNKSAGKVVFATVKGDVHDIGK
NIVSVVLSCNNFEVIDLGVMVPPETILETAKRENADIIALSGLITPSLNEMAYVAEEMKRLNFDIPLMVGGAATSKTHTA-----VHST-A----TV---
-M-
>tr|K4L2I3|K4L2I3_9FIRM 5-methyltetrahydrofolate--homocysteine methyltransferase OX=1131462 OS=Dehalobacter sp. CF. GN=DCF50_p1723 PE=4 SV=1
--IFNELLAR-KILILDGAMGTMLQQKDLSAEGCNEILTLTRPYIVRDIHEAYLKAGADIIETNTFGGTNIVLGEHLRDMEINEAAARLAREAADKPRFV
AGSMGPTTKMLAFGGGITFTDLEEAYCRQTLGLIKGGVDLLIVETCQDTLNIKAAGLGIQRAREVPLVVSVTIESGTMLAGQNIEALYISIQHLKPAAIG
MNCGTGAELMNDHLRTLEGLASCAVSCYPNAGLPDE--EG--GYQETPEEFAGKMAAYAAKGLNIAGGCCGTTDRHIEALAAALAKYAPRQIRA--AERS
SV-AGLEAVWPEEENRPLLVGERANVIGSRKFKELIADEYYEEGSEIARNQVKKGAQIVDVCVANPDRDELKDMVSFLPHVVNKVKAPLMLDTTDPAVLE
AGLRLIQGKAIINSINLERERFDEVVPLLRKFGAAVVVGLIDEQGMALTRERKLEVAGRSYNLLNEYGLSAADIIFDPLTFPVGTGDVKAVETIEGLRLI
KAKYECKTILGISNVSFGLPGREVLNAVFVYLNTVAGLDYAIVNSEKLERYATILAEDLLLTNDQTLKAFTDFYREKKVTE-----QKQTSG--LSVEER
LAGAIVEGSKEGLENDLYEALTKY-RPLEIINGPLMKGMEEVGSLFNRNQLIVAEVLQSAEVMKAAVTILESQMEKA-EEAVKGKILLATVKGDVHDIGK
NLVEIILSNNGYKVVNLGVKVSSEQLIEAARKEAPDAIGLSGLLVKSVQQMLLTAQDLQAAGINTPLILGGAALSRKYTEKIGPVLYARDAMVGLNLLNG
LK-
>tr|C6J513|C6J513_9BACL Methionine synthase OX=621372 OS=Paenibacillus sp. oral taxon 786 str. D14. GN=POTG_03490 PE=3 SV=1
--SLLERMKE-RILILDGAMGTMIQQENLTPAGCNEMLVLTRPDVIRGIHEKYLAAGADLIETNTFGATSVVLAEDIKAREINMAAAKLAIEAAEKPRYV
VGILGPTTKTLSVTGGVTFDELTASYAEQAAALIEAGVDALMLETSQDTLNVKAGSIGIKQAITLPLMISGTIEMGTTLAGQNIEAFYISLEHLNPISIG
LNCATGPEFMRDHIRTLSGLAKAAVSCHPNAGLPDE--NG--IYHESPDSLAQKMSAFAEQGLNIAGGCCGTTPAHIAALANTLKDYRPRELTG--SHLP
AL-SGIEPVYIESANRPYLVGERTNVLGSRKFKRLIVEGKYEEASEIARAQVKNGAQVVDVCVQDPDRDEAEDIKKFLELVVKKVKVPLMIDTTDPKVLD
IALQYCQGKSIINSINLEEEKFERVTPLIHKYGAAVVVGTIDERGQAITREDKLEVAKRSYDLLHKYGLQPEDIIFDPLVFPVGTGDEQAKETIEGIRLI
KEALKVHTVLGISNVSFGLPGREVLNSVFLYECTKAGLDYAIVNTEKLERYAKILAEELIYTNDETLAAFVAAFRNKKVEK-----AETTTQ--LTLEER
LASYVVEGTKEGLIPDLDEALKKY-TALEIINGPLMAGMEEVGRLFNNNELIVAEVLQSAEVMKASVAYLEPFMEKN-ETSVKGKILLATVKGDVHDIGK
NLVEIILSNNGYQIVNLGIKVPPERIIEAYREEKADAIGLSGLLVKSAQQMVTTAQDLRNAGIDVPILVGGAALTRKFTKRIGLVLYAKDAMDGLDLANK
LM-
>tr|F5SG93|F5SG93_9BACL 5-methyltetrahydrofolate-homocysteine methyltransferase OX=997346 OS=Desmospora sp. 8437. GN= PE=3 SV=1
--PVQQRLEE-KILVLDGAMGTQLQGAALTAEGCNEYLNITRPDLIRAIHEEYLEAGADVIETNTFGATRVVLAEGLRAEEINQRAAELAVEAATGPRYV
AGALGPTTKTLSVTGGVTFDQLVDSYREQARALIRGGVDLLLLETSQDTLNVKAAGIGIRQAREVPLMISGTIEMGTMLAGQNVEAFYLSIQHLNPLTVG
LNCATGPEFMRDHLRTLSGLAHCGVSCYPNAGLPDE--EG--RYHETPRGLAQKLAGFAEQGLNVAGGCCGTTPEHIRAIAEALADREPRRSNP--SRFP
AV-SGIEPLYPEADNRPILVGERTNVIGSRKFRNMIREEQYEEAAGIARRQVKGGAQVIDICLADPDRDELEDMERFLHFAVNKVKVPLMIDSTDPHVIE
RALRYSQGKAIINSINLEEDRFREVAPLIHRYGAAVVVGTIDEEGMAVQAEQKLAVARRSYDLLNHYRIPPEDIIFDPLIFPVGTGDRAAGETVEGIRRI
KEAMECSTILGVSNVSFGLPGREVLNAVCLYHCTRAGLDYAIVNTERLERYASIQAELFLFTDDDVLAEFAAFYRDKKPTQ-----KKEVQN--LPLEER
LARYVVEGSKDGLIPDLDKALQKY-KALEIINGPLMKGMDEVGRLFNDNQLIVAEVLQSAEVMKASVSFLEPHMEKT-SQKSKGKILLATVKGDVHDIGK
NLVEIILSNNGFDVINLGIKVPPEQLIEACRRENPDMVGLSGLLVKSAQQMVLTAQDMKAANLDLPVLVGGAALTRKFTDRIGLVLYAKDAMNGLELANR
LR-
>tr|F0SYH1|F0SYH1_SYNGF Methionine synthase (B12-dependent) OX=645991 OS=Syntrophobotulus glycolicus (strain DSM 8271 / FlGlyR). GN= PE=3 SV=1
--LFKTQLEK-KILILDGAMGTMLQRHQLKPDGCNEILNLSQPDLIKAIHEAYLDAGADIIETNSFGATNVVLEEGLRDIELNEISARLAREAADAPRFV
AGSMGPTIRMLTLSAGITFEELEEAYYRQALGLIKGGADLLLVETCQDTLNVKAAGIGIGRAKEIPIMISCTIESGTMLAGQNIQAFYLSVKHLNPAVIG
LNCGTGADGMREHVRTLAGIASCAVSCHANAGLPDE--EG--NYLEQPRAFAAKQAEFARNGLNIAGGCCGTTPEHIKALAEELRDCRPRAGKQ--KAES
AV-SGIEPLWLEKTGRPILVGERSNVIGSRLFRDLIVGEHYEEGSEVARGQVKKGAHVVDICVANPDRDEYHDMVNFLSYVVKKVKVPLMLDSTDAQVVE
AGLKMIQGKAIINSINLELERFEQIVPLIHKYGAAIVVGLIDEQGMALSREDKLRVAERSCQLLERYALQPGDIIFDPLTFPVGTGDPKAKETIEGLRLI
KEKIACKTILGVSNVSFGLPGREVLNAVFVHHNTLAGLDYAIVNAEKHKSYADILAEDLLFTNDRTLKNFTDFYRDKKAVP-----VHVQEQ--LSWDQR
LARNIVDGSKEGLEADLSEGLKTH-TPLELINGPLLKGMDEVGRLFNRNMLIVAEVLQSAEVMKAAVGILEKHMDKT-EEAIKGKLILATVKGDVHDIGK
NLVEIILSNNGYQVINLGVKVSPEEIIKACREHKPDAVGLSGLLVKSVQQMLVTAQEMRAENIKVPLILGGAALSRKFTEKIAPAFYCQDAMEGLKVLQE
YK-
>tr|D5WSZ6|D5WSZ6_BACT2 Methionine synthase OX=562970 OS=Bacillus tusciae (strain DSM 2912 / NBRC 15312 / T2). GN= PE=3 SV=1
--LLERRLKE-AILVLDGAMGTMIQQQGLTAAGCNEVLNLTRPDVITSIHEAYLEAGADIIETNTFGATRVVLAEGLKAYAINRTAAELARRAADGPRFV
AGAMGPTTKTLSVTGGIDFDTLAAAYAEQAKGLLDGGVDLLLVETAQDTLNVKAAGVGIHRAFEVPVMISGTIEMGTTLAGQGIDAFYVSVEHLHPVAVG
LNCATGPEFMTDHLRTLSGLAKTAVSCYPNAGLPDE--EG--HYHESPQSLAEKMAGFARQGVNVVGGCCGTTPEHIRALAQAVRGLPPRTPAA--DHPP
AV-SGVEAVFLEGDNRPLLVGERTNVIGSRKFRELIQSGRFEEAAEIARAQVRGGAQIIDVCLADPDRDEYADMDQFLKYVTRMVKVPLMIDSTDPRVVE
LALQRSQGKAIINSINLEEKRFAQVAPLARRYGAAVVVGTIDEEGMAVTRERKLAVAQRSYQLLEEYGIPPEDLIFDPLVFPVGTGDENAAETVAALRML
KERFRSATILGISNVSFGLPGREVLNAVFLYHCTKAGLDYAIVNPEKLQRYASILAEALLFTGQETLARFHDRFKDRPAGP-----PVRRET--LSLNER
LARCVVEGSKEGLLDDLSEALQSA-SPIEIINGPLMAGMDEVGRLFNDNQLIVAEVLQSAEVMKAAVAYLEPHMEKA-ETAKKAKILLATVKGDVHDIGK
NLVEIILSNNGFEVVNLGIKVAPEVLIEAVRREEPDAIGLSGLLVKSAQQMVVTAQDLRAAGVSLPLLVGGAALTAKFAYRIGLVLYAKDAMEGLEIANR
LV-
>tr|D6XXG6|D6XXG6_BACIE Methionine synthase OX=439292 OS=Bacillus selenitireducens (strain ATCC 700615 / DSM 15326 / MLS10). GN= PE=3 SV=1
--AFRDALKE-RILVLDGAMGTMLQNANLTPEGCNEYLNITAPEVIRTIYHDYLEAGADIIETNTFGATDLVLDDDLLAYELNKAAASIAVEEARAPRFV
AGAMGPTTKSLSVTGGTTFEELSSAYKEQVEGLLDGGVDLLLLETSQDMRNVKAAYTAIEEVLDVPLIISGTIEMGTTLAGQTIESFYISLEHMKPTVVG
LNCATGPEFMQDHLRSLSELSTGFVHCYPNAGLPDE--EG--HYHETPSSLASKLRDFAEKGLNVVGGCCGTTPEHIRAMKEAVRGFAPRQPAQ--ETHH
SI-SGIEPLIYDESLRPILVGERTNVIGSKKFKRLIADGKFEEASEIARAQVKRGAMVVDVCLADPDRDEMADMEQFLHYVINKVKVPLMIDSTDEHVIE
KALTYSQGKAIINSINLEEERFEAVCPLIRRYGAAVVVGTIDEEGMGVSAERKLAIAKRSYELLGKYGIAPEDIIFDPLVFPVGTGDEQAEATVEGIRLI
KKAFRTMTILGVSNVSFGLPGREVLNAAFVYHCTKAGLDYAIVNTEKLERYGSVLADELLFTSDETLAEFTAFYRAKKPQQ-----KVEASK--RTLEER
LANYIIEGTKEGLYTDLDEALAKYPDPLDIINGPLMDGMDEVGKLFNNNELIVAEVLQSAEAMKAAVAHLEPHMEKKEDDRGKGKILLATVKGDVHDIGK
NLVEIILSNNGFQVVNLGIKVASHELIEAVEREDPDYIGLSGLLVKSTQQMVITANDLRERGIDIPILVGGAALTRKFTEKIGLVLYAKDAMNGLSLANK
LA-
>tr|G2TR31|G2TR31_BACCO Methionine synthase OX=345219 OS=Bacillus coagulans 36D1. GN=Bcoa_0889 PE=3 SV=1
--LFEQQLAN-RILILDGAMGTMIQQQHLTAAGCNEYLNLTAPDLIRSIHEAYLEAGADIIETNTFGATSIVLNEGLFAEKINIEAARIAKQAAKKPRFV
AGSMGPTTKTLSVTGGTTFDALKTAYQEQACGLIKGGVDVLLLETSQDLLNVKAAFLGITDAKKLPLLISGTIEMGTTLAGQNIEAFYISVEHMQPAAVG
LNCATGPEFMADSIRTLAGLAKTAVSCYPNAGLPDE--EG--HYHETPESLAVKMKGFAEKGLNIAGGCCGTTPAHIKALNEALAGLPPRQ-PA--KEHH
AV-SGIEPFIYDDSTRPIFVGERTNVIGSRKFRRLIAEGKWEEASEIARTQVKNGAQIIDICLADPDRDEISDMENFISIAVKKVKVPFMIDSTDENVIE
KAFTYCQGKSIVNSINLETERFEKVVPLLKKYGGAVVVGTIDEEGMAVTAERKLEIARRSYDLLDTYGLNPRDLIFDPLVFPAGTGDKQAKETVEGIRLI
KEAMECQTILGVSNVSFGLPGREVLNSVFLYHCTKAGLDYAIVNTEKLERFASIMAEKLLFTSDEALAAFTEYYRGKVQEK-----KAPKST--MTLAER
LANYVVEGTKEGLIPDLEQALKEYPDPLAIINGPLMDGMAEVGRLFNDNQLIVAEVLQSAEVMKASVAFLEPFMEKN-ETSTKGKVLLATVKGDVHDIGK
NLVDIILSNNGYKVVDLGIKVAPADLIHAVRKEKPDVIGLSGLLVKSAQQMVVTAQDLREAGIRQPILVGGAALSRKFTVKIGLVLYAKDAMEGLTLANK
LQ-
>tr|F7U1L6|F7U1L6_BRELA Methionine synthase OX=1042163 OS=Brevibacillus laterosporus LMG 15441. GN= PE=3 SV=1
--TLQEQLAR-KILILDGAMGTMLQQANLTADGCNELLNVTRPDVIRHIHATYFEAGADIVETNTFGATDVVLAEDIRDYELNLAAARIAKEVADEPRYV
AGSMGPTTKTLSLTGGVTFEQLIHAYYRQTKALMEGGVDLLLVETSQDTLNVKAGGIGIRQAYELPIMISGTIEMGTTLAGQNIEAFYVSIEHLKPITIG
LNCATGPEFMRDHLRTLSDLALCGISCYPNAGLPDE--NG--HYHESPQGLAMKMKAFAEKGLNVAGGCCGTTPEHIRALHEALQGITPRENKK--SHAT
AV-SGIEVLYVEDDNRPIFVGERTNVIGSKKFRDLIAAGQFEEGSDIARAQVKRGAAVIDICLADPDRDEYEDMGKFLPYVSRKVKAPLMIDSTDKKVVE
LGLKYSQGKAIINSINLELDRFEEVVPLIHKYGAAVVVGTIDETGMAITRERKLEVATRSYDLLNQFGINPQDIIFDALVFPVGTGDEQAQETIEGIRLI
KQHFLCKQILGVSNVSFGLPGREVLNAVFLYHTTVAGLDYAIVNTEKIERYASILAENLLFTNDETLATFTDFYRQKKKEV-----VKEVSN--LTLEER
LANYVVEGSKDGLIPDLTLALEKY-VPLDIINGPLMKGMEEVGRLFNGNQLIVAEVLQSAEVMKASVAFLEPHMEKS-ESTVKGKILLATVKGDVHDIGK
NLVEIILSNNGYEVINLGIKVAPEQLIAACHQEKPDAIGLSGLLVKSAQQMVITAQDLRSSGIDVPLMVGGAALTRKFTTRIGIVLFAKDAMDGLNLANK
LH-
>tr|L5N9Z2|L5N9Z2_9BACI 5-methyltetrahydrofolate--homocysteine methyltransferase OX=1246484 OS=Halobacillus sp. BAB-2008. GN=D479_06398 PE=4 SV=1
--WFERQLEK-RILILDGAMGTMIQDADLSAEGCNEYLNLTYPDLLEKIHTQYLEAGADIIETNTFGATDLVLDEDLLAEEINIAAAKIARKAVDRPRFV
AGAMGPTTKTLSVTGGTTFDVLAKGYEEQARGLIKGGVDLLLLETSQDMLNVKAAFVGITKATKLPLLISGTIEMGTTLAGQSIEAFYLSLEHMNPVVVG
LNCATGPEFMRDHLRSLSDLATSAVSCYPNAGLPDE--EG--NYHETPESLAQKVAGFAEKGLNLVGGCCGTTPDHIRAIADAVRPYQPRE-RK--DHPH
AV-SGIEPMIYDDPARPILVGERTNVIGSRKFKRLIAEGKFEEASEIARAQVKKGAQVIDICLADPDRDEVTDMEAFMKEVVNKVKVPLVIDSTDVKVIE
KALKYSQGKVIINSINLEEERFKEVLPLVKQYGAALVVGTIDEVGMAVTAERKLEIAKRSHDILKEYAIDPRDIIFDPLVFPVGTGDEQAEATIEGIRLI
KEQLLCQTVLGVSNVSFGLPGREVLNAVYLYHCTKAGLDYAIVNTEKLERFASILADELLYTNEQTLAAFTAFYRGKKKEN-----KVPTST--MTLAER
LAHYVVEGTKEGLIPDLELALAEYPTPLDVINGPLMEGMAEVGRLFNDNQLIVAEVLQSAEVMKASVAFLEPHMEKG-DSSNKGKVLLATVKGDVHDIGK
NLVEIILSNNGFEVVDLGIKVTPVELIEQIKREQPTIIGLSGLLVKSAQQMVLTAQDLKQQNISLPILVGGAALSRKFTHKIGPVLYAKDAMDGLSISNQ
LS-
>tr|H1I4Z7|H1I4Z7_9BACI Methionine synthase OX=666686 OS=Bacillus sp. 1NLA3E. GN=B1NLA3EDRAFT_2846 PE=3 SV=1
--SFNNELKK-RILIMDGAMGTMLQQANLTAEGCNENLNLTVPNVIEEIHLEYLQAGADIIETNSFGATGIVLEEQLLAYEINKAAGLIARRAADKPRFV
AGSMGPTTKTLSVTGGTTFSVLAESYEEQAIGLIDGKVDLLLLETSQDLLNVKAGFFGIQRAKKLPLIISGTIEMGTTLAGQSIEAFYISVQHMNPVAVG
LNCATGPEFMQDHIRSLANIASTSVICYPNAGLPDE--EG--HYHETPDSLAKKLAGFASEGLNIVGGCCGTTPAHIKALSDTMIDYKPRLIPE--NSVH
MV-SGIEAFIYDDTLRPIMVGERTNVIGSRKFKRLIGEGKFEEAAEIARAQVKGGAHVIDLCLADPDRDEVEDMENFIKEVVKKIKVPLVIDSTDDAVIE
KSLTYSQGKAIINSINLEEERFQAIAPLIHRYGAAVVVGTIDEVGMGVTADRKLEIAKRSYDLLNKYKIQPQDIIFDPLVFPVGTGDEQAKATVEGIRLI
KEALKTQTILGISNVSFGLPGREILNSVFLYHCTQAGLDYAIVNTEKLERFASILAEKLLFTTDETLATFTELYRGKKKES-----KQTVPT--MSLSER
LSYYIVEGTKEGLIPDIEEALTIYPAPLDIINGPLMDGMKEVGRLFNGNQLIVAEVLQSAEVMKAAVSFLEPYMEKD-NTTSKGKIILATVKGDVHDIGK
NLVDIILSNNGYEVIDLGIKVSPADLVTAIKREVPDMVGLSGLLVKSAQQMVLTAHDMKQSGIDIPILVGGAALSRKFTDKIGLVLYAKDAMNGLDLANQ
LQ-
>tr|J3AZL1|J3AZL1_9BACL 5-methyltetrahydrofolate--homocysteine methyltransferase OX=1144311 OS=Brevibacillus sp. CF112. GN=PMI08_03877 PE=3 SV=1
--TFREQLSR-KILILDGAMGTMLQQANLTADGCNELLNLTRPDVIRSIHEKYLEAGADIVETNTFGATSVVLAEDVKDLEINIAAARLAKEAVDAPRYV
AGAMGPTTKTLALTGGVTFEELVESYYRQAKGLIIGGVDVLLLETSQDTLNVKAGGIGIRQAVELPVMLSGTIEMGTTLAGQNIEAFYISLEHLKPVTIG
LNCATGPEFMRDHLRTLSGLAQCGVSCYPNAGLPDE--NG--HYHETPQGLAAKMRAFAEQGLNVAGGCCGTTPDHIRAMAEALKDCKPRQATE--QAVS
AV-SGIEVVYVEDDNRPLLVGERTNVIGSKKFRDLIAAGQYEEASDIARAQVKRGAHVIDICLADPDRDEYADMEKFLQFVVKKVKAPLMIDSTDAKVME
LGLRYSQGKAILNSINLELERFEEVAPLIRKFGAAVVVGTIEEAGMAITREKKLEVAKRSYDILNQYGIPPQDIIFDPLVFPVGTGDEQARETVEGIRLI
KEAMQCKTILGVSNVSFGLPGREVLNAVFLYHTTLAGLDFAIVNTEKLERYASILAEALLFTNDETLAAFTEFYRQKKKEV-----RVEASS--LTLEER
LARYVVEGSKDGLVDDLKLALEKY-TPLEIINGPLMAGMEEVGRLFNGNQLIVAEVLQSAEVMKASVSFLEPFMEKS-DSASKGKILLATVKGDVHDIGK
NLVEIILANNGYNVVNLGIKVPPEQLIAACRKEKPDAIGLSGLLVKSAQQMVITAQDLRAAGIDVPMMVGGAALTRKFTSRIGVVLYAKDAMDGLDLVNR
LQ-
>tr|I3DVD2|I3DVD2_BACMT Methionine synthase OX=997296 OS=Bacillus methanolicus PB1. GN= PE=3 SV=1
--SFTDQLNQ-RILIMDGAMGTMLQQANLTAEGCNEHLNLTAPEVIESIHIEYLKAGADIIETNTFGATSIVLAEQLKAYEINKAAARIARKAADRPRFV
AGSMGPTTKTLSVTGGTTFEALADSYEEQAIGLIDGNVDLLLLETSQDLLNVKAGFIGIKRAKILPLIISGTIEMGTTLAGQSIEAFYISVEHMKPAAVG
LNCATGPEFMQDHIRSLANLATTAVSCYPNAGLPDE--EG--QYHETPEILAQKLAGFAEQGLNIVGGCCGTTPDHIRAIADVMKIYKPRLLKQ--DNTH
KL-SGIEPLIYDDSFRPIMVGERTNVIGSRKFKRLIKEGKYEEAAEIARAQVKSGAHVIDICLADPDRDELADMENFIKEVVKKVKVPLVIDSTDERVIE
KALTYTQGKAIINSINLEEERFEAIAPLIHRYGAAVVVGTIDEKGMGVTAERKLEIAERSYELLNKYKISPQDIIFDPLVFPVGTGDEQAKATVEGIRMI
KENFETQTILGISNVSFGLPGREILNSVFLYHCTQAGLDYAIVNTEKLERFASIMAEKLLFTTDESLAAFTEYYRDKKKEA-----KSTLPD--MTLEER
LSYYIVEGTKEGLLQDLELALDSYPSPLDIINGPLMDGMKEVGRLFNDNQLIVAEVLQSAEVMKTAVSFLEPFMEKN-TSTSKGKIILATVKGDVHDIGK
NLVDIILSNNGYEVIDLGIKVAPNELIEAIKNEKPDIVGLSGLLVKSAQQMVITAHDLKKAGISIPILVGGAALSRKFTEKIGIVLYAKDAMNGLSLANK
LQ-
>tr|G9QKJ4|G9QKJ4_9BACI Methionine synthase OX=665952 OS=Bacillus smithii 7_3_47FAA. GN=HMPREF1015_01683 PE=3 SV=1
--PIEHELEK-RILIIDGAMGTMIQQAGLTSNGCNEFLNITAPHVVEWIHRSYLEAGADVIETNSFGGTPLVLNENLRAYEINRRAAEIAKKAAAEPRFV
AGAMGPTTKTLSVTGGIDFESLSKHFEIQARGLIDGGCDLLLLETSQDMLNVKAGFLGIQRAKTLPLMISGTIEMGTTLAGQNIEAFYLSLEHMNPLSVG
LNCATGPEFMTDHIRSLSGLAQSFVSCYPNAGLPDE--EG--KYHETPESLSKKIAGFAEKGLNLVGGCCGTTPEHIRAISEAVKPYPPRKRPN--QHGH
AV-SGIEPLIYDDSMRPLFIGERTNVIGSRKFKRLIIEGKYEEASEIARAQVKGGAHVIDICLANPDRDELSDMENFIKEVVKKVKVPLVIDSTDEKVIE
KALTYSQGKAIINSINLEEERFEKVVPLIKKYGAAVVVGTIDEKGMAVTRERKLEIAERSYDLLHKWGLQPEDLIFDPLVFPVGTGDEQAQETIEGIRLI
KEKLRCLTVLGISNVSFGLPGREVLNAVFLYHCTQAGLDYAIVNTEKLERYASILAEKLLFTNDDTLAAFTAFYRDKKKEH-----KVQELP--KTVEER
LRYYIVEGTKEGLIPDLQKALEIFETPLDIINGPLMDGMAEVGRLFNDNQLIVAEVLQSAEVMKAAVAFLEPFMEKS-DNDSKGKVLLATVKGDVHDIGK
NLVDIILSNNGFKVIDLGIKVAPSELIQAVQKEQPDIVGLSGLLVKSAQQMVMTVQDMKQAGINVPVLVGGAALSRRFTEKIGPVLYAKDAMEGLSLANR
LQ-
>tr|Q2BAQ5|Q2BAQ5_9BACI 5-methyltetrahydrofolate--homocysteine S-methyltransferase OX=313627 OS=Bacillus sp. NRRL B-14911. GN=B14911_27840 PE=3 SV=1
--SLSERMNN-KILIMDGAMGTMLQRADLSAEGCNEYLNLTAPGVIKEIHLAYLKAGADIIETNTFGATSIVLDESLKAYEINRTASLIARKAADQPRFV
AGSMGPTTKTLSVTGGTTFEELSLSYEEQACGLIDGKADLLLLETSQDMLNVKAGYIGIQNAITLPLIVSGTIEMGTTLAGQPIEAFYISLEHMKPLAVG
LNCATGPEFMQEHIRSLSSLADAAVSCYPNAGLPDE--EG--RYHETPESLAEKLAGFASQGLNIVGGCCGTTPEHIKAIADKMEHFAPRKISA--ASAH
KV-SGIEPLIYDDTLRPIMVGERTNVIGSRKFRRLIAEGKFEEASEVARAQVKNGAHVIDICLADPDRDELEDMENFIKEVTKKVKAPIVIDSTDEKVIE
KALIYLQGKSVINSINLEEERFEAIAPLIRLYGAAVVVGTIDEKGMGVSADRKLEIASRSYTLLEKYGIPPEDIIFDPLVFPVGTGDEQAEATVEGIRLI
KERFKTQTILGISNVSFGLPGREILNSVFLYHCTQAGLDYAIVNTEKLERFASILAEKLLFTTDETLAQFTEFYRGKKKEE-----KSLLPD--MSLAER
LAYYIKEGTKEGLLEDLKAALLEYSSPLEIINGPLMDGMKEVGRLFNDNQLIVAEVLQSAEVMKASVSYLEPFMEKG-TSSGKGKIILATVKGDVHDIGK
NLVDIILSNNGYEVIDLGIKVSPSELVEAVKKEKPNMVGLSGLLVKSAQQMVITASDMKQAGIDIPILVGGAALSRKFTDKIGLVMYAKDAMNGLSIADQ
LR-
>tr|K6DA48|K6DA48_9BACI Methionine synthase OX=1117379 OS=Bacillus bataviensis LMG 21833. GN=BABA_10141 PE=4 SV=1
--SFIDQLKK-RILVMDGAMGTMLQQAELTPDGCNEHLNLTAPAVIANIHREYLDAGADIIETNTFGATSIVLDEELKAYEINKIAAMIAVSEVMKPRYV
AGSMGPTTKTLSVTGGTTFDVLSASYEEQAIGLIDGGVDLLLLETSQDMLNVKAGYVGIQKAKTLPLFISGTIEMGTTLAGQTIESFYISVEHMNPVAVG
LNCATGPEFMQDHVRSLAGLAATAVSCYPNAGLPDE--EG--HYHETPETLAKKLSDFAAHGLNIVGGCCGTTPAHIKAMAEAMKEFKPREVRQ--SGVH
MV-SGIDPFIYDDTLRPIMVGERTNVIGSRKFKRLITEGKFEEAAEIARAQVKGGAHVIDLCLADPDREEIVDMENFIKEVVKKIKVPLVIDSTDEKVIE
RALKYSQGKAIINSINLEEERFEAVVPFIHRYGAAVVVGTIDEKGMGVTAERKLEIARRSHDLLNKYKLKSQDLIFDPLVFPVGTGDEQAKATVEGIKLI
KEQLGVQTILGISNVSFGLPGREILNSVFLYHCTQAGLDYAIVNTEKLERFASILAEALLFTTDATLATFTEFYRGKKKES-----KVTGTN--MTLEER
LAYYVVEGTKEGLLPDLDLALESYPAPLEIINGPLMDGMKEVGRLFNDNQLIVAEVLQSAEVMKAAVSHLEPHMEKG-DVSAKGKVILATVKGDVHDIGK
NLVDIILSNNGFQVHDLGIKVTPTELVQAIREEKPDFVGLSGLLVKSAQQMVLTAQDMKEAGISLPILVGGAALSRKFTDKIGLVLYAKDAMTGLSLANQ
LG-
>tr|Q5WGV1|Q5WGV1_BACSK 5-methyltetrahydrofolate--homocysteine methyltransferase OX=66692 OS=Bacillus clausii (strain KSM-K16). GN= PE=3 SV=1
--LFEKQLKQ-SILVLDGAMGTMLQEANLTAAGCNEYLNQTAPHIVSDIYKKYLEAGADIISTNTFGSTSIVLADDLLAYDLSKEAARLARIEADRPRFV
AGAMGPTTKSLSVTGGTTFQELIEAYEEQARALIDGGCDVLLLETSQDMRNVKAAYLGISEARTLPLMVSGTIEMGTTLAGQTVEAFYLSLEHMKPAVVG
LNCATGPEFMRDHIRSLAELAETNVSCYPNAGLPDE--DG--VYHETPDSLVKKLEGFAAKGLNVVGGCCGTTPAHIKKMVEVIKKYPPRKAKT--RQTH
AV-SGIEPLLYDDSMRPLFVGERTNVIGSRKFKRLIEEGEYEQASEIARAQVKRGAHVIDICLADPDRNEQEDMAAFLNYVVNKVKVPLMIDSTDEAVIE
RALTYSQGKAIINSINLEEERFAAVLPLVKKYGAAIVVGTIDETGMAVTAERKLAVAKRSYKLLEKYNIPPHDIIFDPLVFPVGTGDEQAAATVEGIALI
KKELQCLTILGVSNVSFGLPGREVLNAVFLYHCTQAGLDYAIVNTEKLERYASILADRLLFTNDAHLAAFTDFYRGKKTEK-----KVEYAN--MSLEER
LSAYIVEGTKERLETDLAEALRLYDTPLAIINGPLMAGMDEVGRLFNANELIVAEVLQSAEVMKAAVAYLEPHMEKSEQEQGKGKILLATVKGDVHDIGK
NLVDIILSNNGFSIVNLGIKVTSNELLDAIKKEQPTAIGLSGLLVKSAQQMVLTAQDLRQQHVDIPILVGGAALTKKFTDRIGLVVYAKDAMNGLELANR
LT-
>tr|D3G025|D3G025_BACPE 5-methyltetrahydrofolate S-homocysteine methyltransferase OX=398511 OS=Bacillus pseudofirmus (strain OF4). GN= PE=3 SV=1
--LLEQQLKE-RILVLDGAMGTMLQQANLTAEGCNEYLNETAPHVIEGIHRAYFEAGADIVETNTFGATDIVLDDDLKAEELNRVAVEIAKKAAKEPRFV
AGAMGPTTKSLSVTGGTTFDALINSYHEQARGLLSGGADLLLLETSQDMRNVKAAYVGIERAVKVPIMVSGTIEMGTTLAGQTIEAFYLSLEHMKPTVVG
LNCATGPEFMRDHIRSLSELSNTFVSCYPNAGLPDE--EG--HYHESPSSLSKKLMGFAEKGLNIVGGCCGTTPEHIRAMVEAVDGFAPRKLEE--KRGH
AV-SGIEPLIYDDSMRPLFVGERTNVIGSRKFKRLIAEGKYEEASEIARAQVKRGAHVIDICLADPDREELEDMEAFLSHVVNKVKVPLMIDSTDEAVIE
KSLTYSQGKAIINSINLEEERFEAIVPLIKRYGAAVVVGTIDEEGMAVSAKRKLEVAKRSYDLLNKHGLKPSDIIFDPLVFPVGTGDAQAEATVEGIRLI
KEELECLTILGVSNVSFGLPGREVLNAVYLYHCTQAGLDYAIVNTEKLERYASIMAKTLLFTTDESLAEFTAFYRGKKQEK-----KVEASS--MTLEER
LAAYVVEGTKEGLYKDLDQALKSYSDALDIINGPLMDGMDEVGRLFNNNELIVAEVLQSAEVMKASVAHLEPHMEKKADDDGKGKILLATVKGDVHDIGK
NLVEIILGNNGFKIVNLGIKVTSNELIEAIKKENPKAVGLSGLLVKSAQQMVLTAQDLRQQNISIPILVGGAALTRKFTDKIGLVLYAKDAMNGLELANK
LV-
>tr|C6CUS8|C6CUS8_PAESJ Methionine synthase OX=324057 OS=Paenibacillus sp. (strain JDR-2). GN= PE=3 SV=1
--TIQEMMQQ-RILILDGAMGTMIQQADLTADGCNEMLVLTRPDVISTIHEKYLEAGADILETNTFGATSVVLAEDIKAREINLAAAKLARDAADKPRYV
AGALGPTTKTLSVTGGVTFDELVDSYYEQTVALIEGDVDAILLETSQDTLNVKAGSIGIRKARELPIMISGTIEMGTTLAGQSIESFYISLEHLKPISIG
LNCATGPEFMRDHIRSLSEIADSAVSCYPNAGLPDE--NG--HYHESPESLARKMSAFAEQGLNIAGGCCGTTPAHIKALYDTMANYAPRTQYG--THPA
AV-SGIDTVYIEDENRPIMIGERTNISGSRKFKRLIKEGKFDEASEIARSQVKGGAHIIDINLQDTDIDEAYAVHEFLPQVVKKIKVPLMLDSTYDHIIE
LGLKYSQGKAIINSINLEESKFEKILPLIHQYGAAVVMILIDERGQAVSREAKMEVAERSYNLLNKYGMNPEDIIFDPNMFPVGSGDPQAVETIEGIRMI
KEKFKAKTILGLSNISFGLPGREVLNSVYLYHCTKAGLDYAIVNTEKLERYASILAEDLIYTNDDTLAAFVAAFREKKVVK-----KEKVSN--LSLEER
LASYVVEGTKEGLIPDLDIALKKY-TALEVINGPLMRGMEEVGRLFNNNELIVAEVLQSAEVMKASVAHLEQFMEKN-ESSVKGKIILATVKGDVHDIGK
NLVEIILSNNGYKIINLGIKVPPEQLIEAQRKENADIIGLSGLLVKSAQQMVVTAQDMRNAGISAPIMVGGAALTRKFTKRIGLTLYAKDAMDGLDLANK
LM-
>tr|F5L7C2|F5L7C2_9BACI Methionine synthase OX=986075 OS=Caldalkalibacillus thermarum TA2.A1. GN=CathTA2_1722 PE=3 SV=1
--LFEQQLKQ-KILIIDGAMGTMLQQAGLTAEGCNEYLNLTAPHIVEQIHRAYLEAGADIIETNTFGGTALVLNENLLALEINRTAAEIARKVADEPRFV
AGSMGPTTKSLSVTGGTTFEELVAHYREQATGLLLGGVDLLLLETSQDMRNVKAGYIGICQARKVPLLVSGTIEMGTTLAGQNIEAFYLSLEHMQPAAVG
LNCATGPEFMTDHLRSLSQLATTAVFCYPNAGLPDE--EG--NYHESPESLAQKLAAFAEKGLNMTGGCCGTTPEHIKAVAEAVKPYAPRQIPE--DP-H
AV-SGIEPLIYDTSMRPLLVGERTNVIGSRKFKRLIAEGKYEEAAEIARAQVKGGAHVIDICLADPDRDELADMEQFLKHVINKVKVPLMIDSTDEKVIE
KALTYCQGKAIINSINLEEERFKKVVPLIKRFGAAVVVGTIDEQGMAVKAEDKLRIARRSYDLLNKYGLNPKDIIFDPLVFPVGTGDKQAKATIDGLRMI
KEAFECPTILGISNVSFGLPGREVLNAVFLYHCTQAGLDYAIVNTEKLERFASILAETLIFMSDEALANFTAHFRGMRAKE-----KKQTSQ--MSLEER
LANYVVEGTKEGLYADLDQALAKYPNPLDIINGPLMEGMAEVGRLFNDNQLIVAEVLQSAEVMKAAVAYLEPHMEKT-SDSGKGKVILATVKGDVHDIGK
NLVDIILSNNGYKVIDLGINVAPTTLIEVVRQEQPDIIGLSGLLVKSAQQMVLTAQDLKAANIAVPILVGGAALSRQFTEKIGLVLYAKDAMDGLSLANR
LQ-
>tr|D5DBM3|D5DBM3_BACMD Methionine synthase, vitamin-B12 dependent OX=592022 OS=Bacillus megaterium (strain DSM 319). GN= PE=3 SV=1
--LIEQQLKK-RILVIDGAMGTMIQDADLTAEGCNEYLTRTAPHVIQRIHEEYFAAGADIIETNTFGSTSTVLDEDLLAYELNIEAVKLACAARDKPRFV
AGAIGPTTKTLSVTGGITFPELVESYEEQARGLLDGGVDLLLVETCQDMLNVKAAFLGITAAIEVPIMISGTIEMGTTLAGQDIESFYLSLEHMKPLSVG
LNCATGPEFMTDHIRSLSDLATSAVSCYPNAGLPDE--EG--NYHESPELLAQKIKGFADKGLNFVGGCCGTTPAHIKALAEAVKEVAPRSLDR--SHNH
AV-TGIEPLVYDDSMRPLFVGERTNVIGSRKFKRLIAEGKIEEASEIARAQVKNGAHVIDICLADPDREEMEDMEEFIQEVVKKVKVPLVIDSTDEKVIE
KALTYSQGKVIINSINLEEERFDAILPLVKKFGAALVVGTIDETGMAVTAERKVEIAKRSHDLLEKHGFNPKDIIFDPLVFPVGTGDEQAEETVKGIKMI
KEALDCLTILGVSNVSFGLPGREVLNAVYLYHCTQAGLDYAIVNTEKLERYASILANALLFTTDETLSTFTDFYRDKKKEA-----KVEIST--LTLEER
LAMYIVEGTKEGLLPDLEQALAQYDDPLDIINGPLMKGMAEVGRLFNDNQLIVAEVLQSAEVMKASVAFLEPHMEAT-ENDSKGKVILATVKGDVHDIGK
NLVDIILSNNGFKVIDLGIKVTPQQLIEAVKEEKPDIIGLSGLLVKSAQQMVLTAQDLTQSSIDVPIMVGGAALSRKFTDKIGAVLYAKDAMDGLALANK
LQ-
>tr|K6BWK5|K6BWK5_BACAZ 5-methyltetrahydrofolate--homocysteine methyltransferase OX=1131731 OS=Bacillus azotoformans LMG 9581. GN=BAZO_16649 PE=4 SV=1
--TLQEQMQK-KILIIDGAMGTMLQQANLAAAGCNEYLNLTAPHVIEWIHRSYFEAGADIVETNTFGATKLVLDDELKAYEINKVAAELACKVRDEPRFV
AGSMGPTTKSLSVTGGVTFDELVDNYMEQTRGLIDGGVDLLLLETSQDMRNVKAAFVGIEKAKNIPLIISGTIEMGTTLAGQSIEAFYISVEHMKPLAIG
MNCATGPEFMRDHIRSLSDLSITGVSCYPNAGLPDE--DG--KYHESPESLAAKLAGFAEKGLNMAGGCCGTTPDHIQALAEILKDYEPRQIPT--EHHH
VV-SGIEPLLYDDSMRPLFVGERTNVIGSRKFKNLIIDGQLDEAAEIARAQVKNGAHVIDVCLANPDRDELEDMENFLDVLVKKIKVPLVIDSTDEKVIE
RALTYSQGKAIINSINLEEERFEKIVPLIHRYGAAVVVGTIDETGMAVTAERKLEVAERSYHLLDKYGLSPEDIIFDPLVFPVGTGDEQANETVEGIRLI
KEKMRSLTILGVSNVSFGLPGREILNAVYLYHCTQAGLDYAIVNTEKLERFASILAEKLLFTTDEVLAEFTNLYRDKKKEV-----AVQKND--MTLEER
LAYYIVEGTKEGLVPDLELALKEYDSPLDIINGPLMAGMAEVGRLFNENQLIVAEVLQSAEVMKASVSFLEPYMEAT-ENDSKGKVLLATVKGDVHDIGK
NLVDIILTNNGFKVIDLGIKIAPADLIKAIKEEKPDIVGLSGLLVKSAQQMVLTAQDMKQANISVPLLVGGAALSRKFTDRIGPVLYAKDAMNGLDLANR
LQ-
>tr|J9HSE3|J9HSE3_9BACL Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein OX=1200346 OS=Alicyclobacillus hesperidum URH17-3-68. GN=URH17368_2290 PE=3 SV=1
--ALEQVLAE-RIVILDGAMGTMIQQANLHPHGCNEYLNITRPDFIRGIHLAYLEAGADVIETNSFGSTPLVLSEGLQAFSISKRAAELAREAADAPRFV
AGSMGPTTKSLSVTGGATFDELVDSYRIQALGLMAGGCDFLMIETAQDMLNVKAAGRAIELARTIPVMVSGTIEMGTTLAGQNIEAFYLSVEHLRPFAIG
MNCATGPELMRDHMRALAGLASCAVSCHPNAGLPDE--EG--RYLETPFAFAKKMADFAHEGLNMAGGCCGTTPDHIRELRRQLSGLSPRQAVP--MHVH
AV-AGMEALLLQDDARPVIVGERTNVIGSRKFRKLIADGDYDAAAEIARVQVRAGAQVVDICLADPDRDELADMLQLIPLAVRKVKVPMMIDSTDPAVVE
SALKHIQGKAIINSTNLEEPRLARYAELARAYGAALVVGTIDERGMAVTRERKVEIAKRAVSLLERYGLRKQDILIDPLTFPVGTGDEKAEETVEAIRML
REQLECPTILGISNVSFGLPGREVLNAAFLYHCTRAGLGYAIVNSERLERYASILCDRLLFTSDELVAEFTARFREKRVAI-----KAAKES--LSLEER
IASYVVEGSKDGLFADLDEALARY-APLDIINGPLMDGMNEVGRLFNNNELIVAEVLQSAEVMKAAVSYLEPHMEKA-DVQAKGRLILATVKGDVHDIGK
NLVEIILANNGFEVINLGIKVPPEQLIQAIREHKPDMVGLSGLLVKSAQQMVVTAEDFAHAGIDIPLLVGGAALTKKFTLKIGPVIYAKDAMEGLEIANQ
LV-
>tr|J8Q7Q7|J8Q7Q7_BACAO 5-methyltetrahydrofolate--homocysteine methyltransferase OX=1218173 OS=Bacillus alcalophilus ATCC 27647. GN= PE=3 SV=1
--LFETQLER-RILIMDGAMGTMLQQAELTAEGCNEYLNETAPHVIEKIHYDYLKAGADIIETNSFGSTDLVLDDDLKAEELSFQAAALAKKVADQPRFV
AGAMGPTTKSLSVTGGTTFEALIDSYFIQARGLIRGGSDLILLETSQDMRNVKAAFIGIEKAVKLPLMVSGTIEMGTTLAGQNIEAFYLSLEHMKPVVVG
LNCATGPEFMRDHIRSLSELSTGYVSCYPNAGLPDE--EG--HYHESPESLAKKLAGFAEKGLNVVGGCCGTTPAHIQQLRSELLKYEPRKLND--GHAH
AV-SGIEPLLYDESMRPLFVGERTNVIGSRKFKRLIAEGKYEEASEIARAQVKRGAHVIDVCLADPDREEKEDVEEFLKFLVNKVKVPLMIDSTDEEVIE
TALTYSQGKAIINSINLEEERFEKIAPLVHKYGAAVVVGTIDEEGMAVSAKRKLEVALRSHQLLEKYGLNPKDIIFDPLVFPVGTGDEQAEATVEGIKLI
KEALDCLTILGVSNVSFGLPGREVLNAVYLYHCTQAGLDYAIVNTEKLERYASIMAKKLLFTTDETLANFTAFYRGKKAEK-----KVEISN--LSLEER
LASYIVEGSKEGLIKDLDEALAKYEDPLDIINGPLMNGMDEVGKLFNNNELIVAEVLQSAEVMKASVAHLEPFMEKKEGDNGKGKIILATVKGDVHDIGK
NLVEIILGNNGFKIVNLGIKVTSNEIIEAVKKEKPDAVGLSGLLVKSAQQMVLTAQDLRQQEISVPILVGGAALTRKFTDKIGLVLYAKDAMNGLELANR
IV-
>tr|F5LK27|F5LK27_9BACL Methionine synthase OX=944559 OS=Paenibacillus sp. HGF7. GN= PE=3 SV=1
--SLKEQLQK-KILILDGAMGTMIQQEDLSAEGCNEMLVLTRPDVIQRIHEKYFEAGSDIVETNTFGATSVVLAEDIKAREINLVAAKLAVEAARKPRYV
AGALGPTTKTLSVTGGVTFEDLEESYYEQTIALIESGVDAILLETSQDTLNVKAGGIAIQRAIELPIMISGTIEMGTTLAGQNIESFYISLEHLNPISVG
LNCATGPEFMRDHIRTLSGLAGTYISCYPNAGLPDE--NG--HYHESPESLAKKMAAFAEQGLNIAGGCCGTTPAHIRALAETLSAYKPRTELG--THPS
AV-SGIETVYIEPENRPYMVGERTNVLGSRKFKRLIAEGKYEEASEIARAQVKGGAHVIDVCLQDPDRDETEDMIKFLELVVKKIKVPLMIDSTDTRVIE
LGLKHSQGKAIINSINLEEEKFEKVLPLIHRYGAAAVVGTIDERGQAITREDKLEVAQRSHDLLHKYGMNAEDIIFDPLVFPVGTGDQQAKETIEGIRLI
KEAMATKTILGLSNVSFGLPGREVLNAVYLYHCTKAGLDYAIVNTEKLERYASILAEKLIYTNDETLAEFVAHFRVKKVEK-----KEKIST--LTLEER
LASYVVEGTKEGLLPDLEQALQKY-SPLEVINGPLMEGMAEVGRLFNNNELIVAEVLQSAEVMKASVAYLEQFMEKN-ESAVKGKIILATVKGDVHDIGK
NLVEIILSNNGYQIVNLGIKVPPEQLIEAFRKEKPDAIGLSGLLVKSAQQMIITAQDLRNAGIDVPIMVGGAALTRKFTKRIGLVLYAKDAMDGLDIANK
LS-
>tr|Q9KCE1|Q9KCE1_BACHD 5-methyltetrahydrofolate S-homocysteine methyltransferase OX=272558 OS=9153 / C-125). GN= PE=3 SV=1
--LFEQQLER-KIVILDGAMGTMLQAANLTADGCNEYLNETAPHVVEDIHRAYLEAGADVIATNTFGATDIVLDDDLKAEELNICAVKIAKRVAEEPRFV
AGAMGPTTKSLSVTGGATFEQLIESYRQQATGLIKGGADILLLETSQDMRNVKAAYLGLSQAVKLPLIISGTIEMGTTLAGQNIEAFYLSLEHMNPVVVG
LNCATGPEFMRDHLRSLSDLATCSVSCYPNAGLPDE--EG--NYHESPESLAAKLAGFAEKGLNMVGGCCGTTPDHIRALLDVMKQFEPRQPKG--DHPH
SV-SGIEPLLYDDSMRPLFVGERTNVIGSRKFKRLIEEEKYEEASEIARSQVKKGAHVIDVCLADPDRDEMEDMEEFLKFVINKVKVPLMIDSTDEKVIE
QALTYSQGKAIINSINLEEERFEKVVPLVHKYGAAVVVGTIDEEGMAITAEKKLAVAKRSYDLLNKYNIRPSDIIFDPLVFPVGTGDEQANETVEGIRRI
KEELECLTILGVSNVSFGLPGREVLNAAYLYHCTQAGLDYAIVNTEKLERYASILSRKLLFTTDETLAEFTAFYRGKKAEK-----KVETSN--LTLEER
LANYIVEGSKDGLTEDLDKALAKYDDPLDIINGPLMNGMDEVGRLFNNNELIVAEVLQSAEVMKASVAHLEPHMEKKADDHGKGKIILATVKGDVHDIGK
NLVEIILSNNGFRIVNLGIKVTSNELIEAVARENPDAIGLSGLLVKSAQQMVLTAQDLKQQQISIPILVGGAALTRKFTNKIGLVVYAKDAMNGLELANK
LM-
>tr|E0RAT1|E0RAT1_PAEP6 Methionine synthase I, cobalamin-binding domain protein OX=349520 OS=Paenibacillus polymyxa (strain E681). GN= PE=3 SV=1
--SLQDALQR-RILLLDGAMGTMIQQEDLSPDGCNEMLVLTRPDVIQGIHEAYLKAGADLIETNTFGATSVVLADDIRAREINLVAAKLARNAVDKPRFV
VGAMGPTTKTLSVTGGVTFAELIDSYQEQALALIEGGVDVLLLETSQDTLNVKAGSIGIRQAIELPLMISGTIEMGTTLAGQNIESFCISLEHLHPISIG
LNCATGPEFMRDHIRSLSEMSSAAISCYPNAGLPDE--NG--QYHESPDSLARKMAAFAEKGLNIAGGCCGTTPEHIRVMSESMAQFEPRPLVG--HHPP
AV-SGIEPVYIEQDNRPYMVGERTNVLGSRKFKRLIVEGKYEEASEIARAQVKSGAHVIDICVQDPDRDEMTDMEAFLKLVVNKVKVPLVIDTTDIKVID
KALQYSQGKAIINSINLEEEKFEKMAPLIHKYGAAVVVGTIDERGQAISREDKLEVARRSYDLLNRYGLAAEDLIFDTLVFPVGTGDEQAKETIEGIRII
KEALGVHTILGISNVSFGLPGREVLNSVYLYECTKAGLDYAIVNTEKLERYASILAEDLIYTNDDTLSAFVAAFRNKKVEK-----KEKISN--LSLEER
LASYVVEGSKEGLIPDLEQALVKY-SSLEIINGPLMKGMEEVGRLFNNNELIVAEVLQSAEVMKASVAYLEPFMEKN-ESSVKGKILLATVKGDVHDIGK
NLVEIILSNNGYHIVNLGIKVPPERIIEAYREEKADMIGLSGLLVKSAQQMVLTAQDLKNANIDIPIMVGGAALTRKFTKRIGLVAYAKDAMDGLDIANK
LM-
>tr|G4HFP3|G4HFP3_9BACL Methionine synthase OX=743719 OS=Paenibacillus lactis 154. GN=PaelaDRAFT_2804 PE=3 SV=1
--SLQEVLKE-RILILDGAMGTMIQREDLTADGCNETLVIYRPDVIQNIHEQYLAAGADLIETNTFGATSVVLAEDILAREINLEAARLARAAADKPRYV
VGAMGPTTKTLSVTGGVTFAELIASYEEQAIALIEGKVDALLLETSQDTLNVKAGSIGIRQAITLPIMISGTIEMGTTLAGQNIEAFYISLEHLNPISIG
LNCATGPEFMRDHIRSLSEMSRSAISCYPNAGLPDE--NG--QYHESPESLAQKMAAFAEKGLNIAGGCCGTTPEHISALKDAMSRFNPRPLTG--THLP
AL-SGIEPVYIEQDNRPYMVGERTNVLGSRKFKRLIVEGKYEEASEIARAQVKNGAHIIDICVQDPDREEAEDMVKFLELVAKKVKVPLMIDTTDPAVID
IALQYSQGKAIINSINLEEEKFEKVIPLVHKYGAAVVVGTIDEKGQAITREDKLKVAKRSYDLLHKYGVSPEDIIFDTLVFPVGTGDEQAKETIEGIRLI
KEAMKVHTILGISNVSFGLPGREVLNSVYLYECTKAGLDYAIVNTEKLERYASILAEDLIYTNDETLAAFVAAFRDKKVEK-----KEKVSN--LSLEER
LASYVVEGSKEGLIPDLNEALKKY-GPLDIINGPLMAGMTEVGRLFNNNELIVAEVLQSAEVMKASVAHLEPFMEKN-ETSVKGKIMLATVKGDVHDIGK
NLVEIILSNNGYEIVNLGIKVPPEQIIEAYRREKPDAIGLSGLLVKSAQQMVLTAQDLKNAGIDVPIMVGGAALTRKFTKRIGMVLYAKDAMEGLDLANK
LS-
>tr|F9DUC7|F9DUC7_9BACL 5-methyltetrahydrofolate-homocysteine methyltransferase OX=1027292 OS=Sporosarcina newyorkensis 2681. GN= PE=3 SV=1
--PIEEQLDK-RILIIDGAMGTMLQAEDLSTEGCNEYLNVLRPDILEKIHDEYLEAGADIICTNTFGGTPLVLNEALRAHEINTKAVEIAKASAAKPRFV
AGAIGPTTKTLSITGGITFDELSNDFYVQAKALVEAGSDLILMETSQDMLNVKAGTIGIKKAREVPIMISGTIEMGTTLAGQSIEAFYISIGHVNPLSVG
LNCATGPEFMTDHLRSLSDLATSYVTCYPNAGLPDE--EG--HYHESPESLSKKLEGFAEKGLNMVGGCCGTTPEHIRAIREAVKDKAPRQMPE--KLGH
AV-SGIEPLLYDDTLRPLLIGERTNVIGSRKFKKLIIEEKFEEASEIARAQVKRGAHVLDICLANPDRDELIDMTRFMKEVVKKVKVPLVIDSTDENVIA
EALKYSQGKAIINSINLEEERFDAVLPLVKKYGAAVVVGTIDEIGMAVTRERKLEIALRSYDLLNKWGIAPEDIIFDPLVFPVGTGDEQAVETIEGIRLI
KEKLRTLTTLGVSNVSFGLPGREVLNAVYLYHCTQAGLDYAIVNTEKLERYASILANDLLFTTDETLADFADFYRDKKKEK-----TEDDIP--KTVPER
LAYYVVEGTKEGLIPDLEAALQTYDAPLDIINGPLMEGMAEVGRLFNDNQLIVAEVLQSAEVMKASVSYLEQFMEKKEDDSGKGKIILATVKGDVHDIGK
NLVDIILSNNGFKVIDIGIKVTPAALIEVIRKEKPDIVGLSGLLVKSAQQMVLTAQDFKAAGIDLPVMVGGAALTRRFTEKIGPVIFAKDAMQGLDLANR
LQ-
>tr|E6U1T9|E6U1T9_BACCJ Methionine synthase OX=649639 OS=/ JCM 9156 / N-4). GN= PE=3 SV=1
--LFEQQLRK-KILIFDGATGTMFQQANLTAEGCNEYLNIVSPHVVERIHHEYFKAGSDIIETNTFGATSIVLDDDLIAEEVNFKSAQLARRAADEPRFV
AGAMGPTTKAISVTGGVTFEQLIDTYEEQARGLIRGEVDVLLLETSQDMRNVKAAFLGIQRAKTLPLIVSGTIEMGTTLAGQSIEAFYLSLEHMNPVMVG
LNCATGPEFMREHIRSLSNLATTAVSCYPNAGLPDE--EG--NYHESPESLAKKIAGFAEKGLNMVGGCCGTTPAHIKALADAIKPFSPRKVPE--DHPH
AV-SGIEPLIYDEDMRPLMVGERTNVIGSRKFKNLIADGKYEEASEIARAQVKNGAHIIDICLADPDREELEDMEHFLQQVINKVKVPLMIDSTDDAVIE
KALTYSQGKAIINSINLEEERFEKVAPLIRQYGAAVVVGTIDEIGMATTADRKLEVAKRSYDLLNKYGLNPKDIIFDPLVFPVGTGDEQAKETVDGIKLI
KEALDCLTILGVSNVSFGLPGREIVNAVYLYHCTKAGLDYAIVNTEKLERFASIMAETLLFTSSETLAKLVEFYRGKKSTV-----KKEVNN--LPLEER
LAHYVVEGTKEGLIPDLEKALEKFSDPLEIINGPLMTGMAKVGELFDKNQLIVAEVLQSAEVMKAAVAYLEDFMEVK-DDSGKGKVILATVKGDVHDIGK
NLVEIILSNNGFRVVDLGIKVTSQTLIDAVRKEKPDMIGLSGLLVKSAQQMMLTAQDLKQSEVSIPILVGGAALSRKFTDKIGLVMYAKDAMDGLHIANQ
LQ-
>tr|L0EE38|L0EE38_9BACL 5-methyltetrahydrofolate--homocysteine methyltransferase OX=717605 OS=Thermobacillus composti KWC4. GN=Theco_1742 PE=4 SV=1
--TLQEAMKH-RILILDGAMGTMIQQANLTAAGCNEMLVLTRPDVIRGIHEAYLDAGADIIETNTFGATSVVLAEGIKAREINLAAARLAAEAAAKPRYV
AGSMGPTTKTLSVTGGVTFDELSDSYYVQALALIEGGVDALLIETCQDALNVKAAGIGVHRARKLPVMISGTIEMGTTLAGQNIESFYISLEHLEPVSIG
LNCATGPEFMRDHIRSLASIAKTAVSCYPNAGLPDE--NG--HYHESPESLARKMEQFAREGLNIAGGCCGTTPAHIRALAEALAPYKPRTEAG--SHPP
AV-SGIETVYIEPENRPYFVGERTNVLGSRMFKRLIAEGKYEEAAEIARAQVKNGAHVIDVCLQDPDRDELADMTRFLEQVVKKVKVPLVIDTTDPRVIE
ASLKFSQGKAIINSINLEEEKFERVVPLVKKYGAAVVVGTIDERGQAIAREAKLEVARRSYDLLNKYGLQPEDIIFDPLVFPVGTGDEQAKETIEGIRLI
KQEMRCQTILGISNVSFGLPGREVLNSVFLYECTKAGLDYAIVNTERLERYASILAEALIYTNDETLAAFVAAFRDKAVEK-----KAKTES--LTLEER
LANYVVEGSKDGLFADLDEALKKY-APLDIINGPLMRGMEEVGRLFNNNELIVAEVLQSAEVMKASVSYLEPHMEKT-ETSVKGKIMLATVKGDVHDIGK
NLVEIILSNNGYEIVNLGIKVPPEAIIEAQRRENADIIGLSGLLVKSAQQMVTTAQDLKAAGIDTPILVGGAALTRKFTKRIGLVLYAKDAMNGLELANK
LM-
>tr|K4ZD72|K4ZD72_PAEAL Methionine synthase MetH OX=1206781 OS=Paenibacillus alvei DSM 29. GN= PE=4 SV=1
--TIQEQLHE-RILILDGAMGTMIQQADLKPQGCNEMLVLTRPDVISRIHEQYLEAGADILETNTFGATRIVLADDIRARELNVAAAKLAVEAAAKPRFV
AGAMGPTTKTLSVTGGVTFDELIDSYYEQAVALIEAGVHMLLLETSQDTLNVKAGSIAIQRAITLPLMISGTIEMGTTLAGQNIESFYISLEHLKPISVG
LNCATGPEFMRDHLRTLASIANSAISCYPNAGLPDE--NG--HYHESPESLARKIATFAEQGLNIAGGCCGTTPEHIRVLRETLLEHAPRTTFG--EHPP
AV-SGIETVYVEDESRPYMVGERTNVLGSRKFKRLIAEGKFEEAAEIARSQVKNGAHVIDVCVQDPDRDEAHDIEQFLQEVVKKVKAPLVIDTTDAKVLE
LALKYSQGKAIINSVNLELEKFDHVVPLVHRYGATLVVGTIDERGQAITREGKLEVAKRSFDILNNYGILPENIIFDPLVFPVGTGDEQAKETIEGIRLI
KEAIKVQTILGISNISFGLPGREVLNSVFLYECTRAGLDYAIVNTEKVERYASILAEDLLYTNDETLAAFVAAFRNRKVEK-----KEKTSN--LPLDER
LASYVVEGTKEGLIPDLTAALQKY-TPLEVINGPLMKGMEEVGRLFNNNELIVAEVLQSAEVMKASVSFLEPHMEKN-ESAVKGKILLATVKGDVHDIGK
NLVEIILSNNGYEIVNLGIKVPPDQLIEAYRKEKPDAIGLSGLLVKSAQQMVITAQDLRTAGIDVPILVGGAALTRKFTKRIGLVLYAKDAMDGLDLANK
IM-
>tr|I4X8J9|I4X8J9_9BACL Methionine synthase OX=1185653 OS=Planococcus antarcticus DSM 14505. GN= PE=3 SV=1
--LIEQQLEK-RILIIDGAMGTMIQNVDLSPEGCNEYLNIVRPDVIEDVHTAYLEAGADILCTNSFGGTPIVLDEGIQAAEINRRAVEIAKKAAYAPRFV
AGAIGPTTKTLSVTGGATFDEMRENFYVQAKALIEGGADLILLETSQDMLNVKAATIGIKQAIELPIMVSGTIEMGTTLAGQSIEAFYISIEHVKPLSVG
LNCATGPEFMTDHIRSLSELSDGYVSCYPNAGLPDE--EG--HYHETPESLAKKLRGFADKGLNVVGGCCGTTPAHIKAVREAMEGLPPRKPDP--VHGH
VV-SGIEPLQYDETMRPLFIGERTNVIGSRKFKRLIVDGQFEEASEIARAQVKNGAHVIDICLANPDRDEVEDMTHFMKEVVKKVKVPLVIDSTDEEVIE
VALKFSQGKAIINSINLEEERFEAVMPLVKKYGAAVVVGTIDEVGMAVTRERKLEIAKRSYDLLNKWGLAPEDIIFDPLVFPVGTGDQQAVETIEGIRLI
KEKLRALTILGVSNVSFGLPGREVLNAVYLYHCTQAGLDYAIVNTEKLERYASIMANELLFTTDATLADFTAFYRDKKKEK-----TKDDIP--KTVPDR
LAYYIIEGTKEGLVPDLEKALEIYDEPLDVINGPLMKGMAEVGRLFNDNQLIVAEVLQSAGVMKAAVSFLEQFMEKKEDDSGKGKIVLATVKGDVHDIGK
NLVEIILSNNGFKVIDVGIKVTPATLIEVIRKEKPDMIGLSGLLVKSAKQMVITAQDFKEAGIDVPILVGGAALSRRFTEKIGPVIYAKDAMQGLDLANR
LQ-
>tr|H3SBQ7|H3SBQ7_9BACL Methionine synthase OX=1131935 OS=Paenibacillus dendritiformis C454. GN=PDENDC454_04716 PE=3 SV=1
--TLEERLQE-RILILDGAMGTMIQQADLLPEGCNEMLVLTRPDVISRIHEQYLEAGADILETNTFGATGIVLAEDLRARELNLAAAKLAVEAAQKPRYV
AGAMGPTTKTLSVTGGVTFEQLVESYYEQALALIEAGVDALLLETSQDTLNVKAGSIAIQRAQKLPLMISGTIEMGTTLAGQNIESFYISLEHLNPVSIG
LNCATGPEFMRDHLRSLSAISRAAISCYPNAGLPDE--NG--HYHESPESLARKIATFAEQGLNIAGGCCGTTPEHIRVLKEELDKYEPRRQAG--SHPP
AV-SGIETVYIENESRPYMVGERTNVLGSRKFKRLIREGKIEEAAEVARAQVKSGAHVIDVCLQDPDRDEAEDMRVFLQEVVKKVKVPLVIDTTDPEVLE
LALTYTQGKAIINSVNLELEKFENVVPLVHRYGASLVVGTIDERGQAITREDKLAVAKRSYDILNDFGIEPENIIFDPLVFPVGTGDEQAKETIEGIRLI
KEAMRCQSILGVSNISFGLPGREVLNSVFLYECTKAGLDYAIVNTEKLERYASILSEALLYTNDETLAEFVAAFRNRTVEK-----KVKTND--LPLEER
LASYIVEGTKEGLIPDLTLALEKY-PPLDIINGPLMKGMEEVGRLFNNNELIVAEVLQSAEVMKASVAFLEPHMEKN-ESAVKGKILLATVKGDVHDIGK
NLVEIILSNNGYEIINLGIKVPPEQLIEAYRKEKPDAIGLSGLLVKSAQQMVVTAQDLRSAGIDVPIMVGGAALTRKFTKRIGLVLYAKDAMEGLDLANK
LM-
>tr|G6GE66|G6GE66_9FIRM Methionine synthase OX=871968 OS=Desulfitobacterium metallireducens DSM 15288. GN=DesmeDRAFT_0298 PE=3 SV=1
--RFEEELGK-RILIIDGAMGTMLQRANLTVKGCNEILTLTRPEVIRSVHEAYLEAGADLIETNTFGATTVVLAENLRDQELNRESAKIAREAADRPRFV
AGSMGPTTKSLSLTGGVTFEELEEAYYRQAVILIEGGVDVLLVETAQDTLNVKAAGSGIQRALELPVMVSGTIEMGTTLAGQNIEAFYVSIAHLHPISVG
LNCATGPEFMRDHIRSLAQIADCGVSCYPNAGLPDE--DG--HYHEEPEGLAHKMVGFAEKGLNIAGGCCGTTPEHVRALTKALQGYSPRPIEA--HHLS
AV-SGLEPVYAEDENRPLIVGERTNVIGSKKFRDLIADGHFEEASEIARAQVKKNAQVIDVCLANPDRDEYADMAEFLPYVVKKVKAPLMIDSTDPKVIE
LGLKRSQGKAIINSINLELTRFNEVVPLLRTYGAAVVVGTIDEQGMAITKEKKLEVAKRSYDVLEK-GVPAEDIIFDPLTFPVATGDETARETVEGIRLI
KQAFQCKTILGVSNVSFGLPGREVLNAVFLYHTTKAGLDYAIVNAEKLVRFASLLADDLLFTNEETVSRFAEFYRNKTVQS-----KVEQKN--LSLEER
LGQYVIEGSKEGLFKDLEEGLQKY-GALELINGPLMKGMGEVGRLFNANQLIVAEVLQSAEVMKAAVTYLEPYLEKK-DAAVKGKILLATVKGDVHDIGK
NLLEIILSNNGFDVVNLGIKVSPEQIIAACEKEKPDAIGLSGLLVKSAQQMIVTAQDLKNAGISLPLLTGGAALTARFVERIGPVLYAGDAMKGLELANQ
YV-
>tr|I0BIK7|I0BIK7_9BACL Methionine synthase OX=997761 OS=Paenibacillus mucilaginosus K02. GN=B2K_15990 PE=3 SV=1
--SLQEQLKK-KIMILDGAMGTMIQQENLTEAGCNEILVVTRPDVIQKIHEAYFAAGADMVETNTFGATSVVLAEDLRARELNLAAAKLAIEAANKPRYV
IGAMGPTTKTLSVTGGVTFDELVESYQEQAEALIEAGVDALLLETSQDTLNVKAGSIGIRSAVKLPLMISGTIEMGTTLAGQNIESFYVSLEHLNPVSFG
LNCATGPEFMRDHIRTLSEIAGTAVSCYPNAGLPDE--NG--KYHESPESLALKLAGFAEQGLNIAGGCCGTTPDHIRAMAETLGKFEPRKQAG--VHPP
AI-SGIETVYVEPDNRPIMVGERTNISGSRKFKRLIKEGKFEEASEIARTQVKNGAHIIDINLQDTDIDEAYAINEFLPQVVKKVKVPLMIDSTYDHIIE
LGLKYSQGKAIVNSINLEESKFEAIVPLLHKYGAAVVMILIDERGQAVSRQAKMEVADRAYELLKKYGMKPQDIIFDPNMFPVGSGDPQAVETIEGIRMI
KEKYETMTILGLSNISFGLPGREVLNSVYLYHCTKAGLDYAIVNTEKLERYASILAEELIFTNDDTLAKFVAYFRVKKVEK-----KEKISN--LTLEER
LASYVVEGTKEGLIPDLEEALKKY-APLDIINGPLMKGMEEVGRLFNNNELIVAEVLQSAEVMKASVAHLEQYMEKA-DSAVKGKIILATVKGDVHDIGK
NLVEIILSNNGYKIVNLGIKVPPEQLIEAYRKEKPDAIGLSGLLVKSAQQMVVTAQDMKNAGIDVPILVGGAALTRKFTKRIGMVLYAKDAMDGLDIANK
LS-
>tr|F2F7E5|F2F7E5_SOLSS Methionine synthase I, cobalamin-binding domain OX=1002809 OS=Solibacillus silvestris (strain StLB046) (Bacillus silvestris). GN= PE=3 SV=1
--PIHEQLQK-RILIIDGAMGTMLQAENLTYEGCNENLVLTRPDVLGKIHREYLAAGADIICTNTFGGTPLVLDEDLKAVEINKRAVEIALEAAKEPRFV
AGAIGPTTKTLSVTGGITFEELEENFYIQAKALIEAGADLLLMETSQDMLNVKAGTIAIHRAKELPVMISGTIEMGTTLAGQSIEAFYISIEHIKPLSVG
LNCATGPEFMTDHIRSLAELSNGYISCYPNAGLPDE--EG--CYHETPDSLSKKLQGFAEKGLNIVGGCCGTTPAHIAAIREAVDGYKPREPKD--VHGH
VV-SGIEPLQYDESMRPLFIGERTNVIGSRKFKNLIVDGKFEEAAEIARAQVKNGAHVIDICLANPDRDEVEDMKNFMQEVVKKVKVPLVIDSTDEKVME
VALKFSQGKAIINSINLEEERFDAVMPLVKKYGASLVVGTIDETGMAITREQKLEVAKRSYKLLEKWGMSAEDIIFDPLMFPVGTGDEQAEETIEGIRLI
KEHLGCLTVLGVSNVSFGLPGREVLNAVYLYHCTQAGLDYAIVNTEKLERYASILANDLIFTNDETLAVFTDFYRDKKKDA-----VVKELP--ATVEER
LAYYILEGTKEGLIEDLNAALEKFDTPLDIINGPLMAGMAEVGKLFNENQLIVAEVLQSAGVMKAAVAHLEQFMEKGDTSANKGTMVLATVKGDVHDIGK
NLVDIILSNNGYRVVDLGIKVTPAQLIETIRREKPDFIGLSGLLVKSAQQMVITAQDFKEAGIDIPILVGGAALSRRFTEKIGPVIYSKDAMQGLEQANR
LM-
>tr|K9AHQ2|K9AHQ2_9BACI Methionine synthase OX=1231627 OS=Lysinibacillus fusiformis ZB2. GN=C518_4036 PE=4 SV=1
--SIEEQLEK-RILILDGAMGTMLQNENLAAEGCNENLVLTRPDVIEKIHHKYLEAGADIICTNTFGGTPLVLNEDLKAEEINKRAVEIARQAVDRPRFV
AGAMGPTTKTLSVTGGITFDELEENFYVQAKALIEAGADVLLLETSQDMLNVKAGTLGVKRAKELPVMISGTIEMGTTLAGQTIDAFYISIEHIKPLSVG
LNCATGPEFMTDHIRSLAELSTGYISCYPNAGLPDE--EG--CYHESPESLSQKLKGFAEKGLNIVGGCCGTTPAHIAAIREVLKDEKPRQLPE--KHGH
AV-SGIEPLLYDDSMRPLFIGERTNVIGSRKFKNLIIDGKFEEAAEIARAQVKNGAHVIDICLANPDRDELADMRGFMQEVVKKVKVPLVIDSTDEKVIE
EALKFSQGKAIINSINLEEERFDVVLPLVKKYGASLVVGTIDEKGMAVDRHRKLEIAERSYQLLEKWGIAPEDIIFDPLMFPVGTGDEQALETIEGIRLI
KEKLQTLTVLGVSNISFGLPGREVLNAVYLYHCTQAGLDYAIVNTEKLERYASILANDLLFTNDETLAVFTDFYRDKKKEK-----TEADIP--KTVEGR
LAYYILEGTKEGLIEDLDAAREIFEAPLDIINGPLMEGMAEVGRLFNDNQLIVAEVLQSAGVMKAAVAHLEQFMEKDEESAGKGKMVLATVKGDVHDIGK
NLVDIILSNNGYKVVDLGIKVTPAQLIEAIRKEKPDFIGLSGLLVKSAQQMVITAQDFKEAGIDVPILVGGAALSRRFTEKIGPVIYSKDAMQGLEQANL
LM-
>tr|B7GLS5|B7GLS5_ANOFW Methionine synthase I containing methyltransferase and cobalamin-binding domains OX=491915 OS=Anoxybacillus flavithermus (strain DSM 21510 / WK1). GN= PE=3 SV=1
--SLFAQLEK-KILIIDGAMGTMIQAANLTADGCNEYLTLTAPHVISHIHEAYFAAGADIVETNTFGATRIVLDENLLALELNMEAAKLAKRAAEKPRFV
AGSMGPTTKTLSVTGGATFAELISSYEEQARGLLLGGVDLLLLETCQDTLNVKAAFLGITKAKQVPLMISGTIEMGTTLAGQTIESFFISVQHMKPFAIG
LNCATGPEFMTDHLRSLASLANTAVSCYPNAGLPDE--EG--HYHETPEMLAKKIRQFAEKGLNIVGGCCGTTPQHIQAIAEAVRDIPPRAIPK--QAMH
AV-SGIDALIYDETMRPLFVGERTNVIGSRKFKRLIAEGKYEEAAEIARAQVKNGAHVIDICLADPDRDEKEDMEQFIQQVVKKVKVPLVIDSTDEDVIA
CALSYSQGKAIINSINLEEERFEKIVPLLHQYGAAVVVGTIDEQGMAIEAKRKLDIALRSYDLLNKYGVSPHDIIFDPLVFPIGTGDEQAKETIEGIRLI
KQHLNCLTMLGISNVSFGLPGREVLNSVFLYHCTQAGLDYAIVNTEKLERFASILAEALLFTNDETLNAFIQFYRDKTKQP-----KQTNVH--MTLEER
LAAYVVEGTKDGLIEDLTLALQTYS-PLDIINGPLMNGMDEVGRLFNDNQLIVAEVLQSAEVMKAAVAFLEPYMEKN-ETSVKGKVLLATVKGDVHDIGK
NLVDIILSNNGFHVVDLGIKVTPQQLIEAVRHEQPDMIGLSGLLVKSAQQMVLTAQDLKQAGISLPILVGGAALSRKFTDKIGIVLYAKDAMEGLTLANR
IV-
>tr|A8FBU3|A8FBU3_BACP2 Methionine synthase OX=315750 OS=Bacillus pumilus (strain SAFR-032). GN= PE=3 SV=1
--TITEQLKK-RILVLDGAMGTMIQNANLTAEGCNEYLNVTAPHIIRTIHKEYLEASADLIETNTFGATKLVLDEGLLAYELNVRAAQLAKDEAKRPRFV
VGAMGPTTKTLSVTGGTTFDELVRNYEEQARALIDGKCDALLLETSQDMLNVKAGFKGIQEAIELPLMVSGTIEMGTTLAGQDIEAFYISLEHMKPMSVG
LNCATGPEFMTDHIRTLSSIAKSAVSCYPNAGLPDE--EG--QYHESPASLAKKISAFAKEGLNIVGGCCGTTPAHIQALSDEVRTIQPRHITH--ESQH
TV-SGIEPLIYDESMRPLFVGERTNVIGSRKFKRLIAEQKFEEASEIARAQVKNGAHVIDVCLADPDRDEIADMEGFLQEAMKKVKAPFVIDSTDKHVIE
KALTYSQGKAIINSINLEEERFEEILPLVKLYGGALVVGTIDETGMAVTAERKLEIAVRSHDLLKKYGIPASDIIFDPLVFPVGTGDEQAEETIKGIKMI
KEKLECLTILGISNVSFGLPGREILNAVYLYHCVQAGLDYAIVNTEKLERFASILAETLLYTNDQTLAEFTQFYRGKKKTE-----KKPKVS--LPLDER
LALYVVEGTKEGLIDDLSLALEQYESPLHIINGPLMQGMAEVGRLFNQNELIVAEVLQSAEVMKASVSYLEQYMEKQ-HASGKGKILLATVKGDVHDIGK
NLVDIILSNNGFQVVDLGIKVTPQTLIEAVQKEKPDMIGLSGLLVKSAQQMVLTAQDLQKANISVPILVGGAALSRKFTKKIGPVLYAKDAMDGLSLANE
LK-
>tr|Q65LG4|Q65LG4_BACLD Putative 5-methyltetrahydrofolate--homocysteine methyltransferase MetH OX=279010 OS=Bacillus licheniformis (strain DSM 13 / ATCC 14580). GN= PE=3 SV=1
--NINDQLKK-KILVLDGAMGTMIQDAGLSAAGCNEFLSITAPHVIQGIHEAYLEAKADIIETNTFGATRLVLDEDLRAYEVNLASVKLAKAAAEKPRFV
AGAMGPTTKTLSVTGGTTFDELIDNYEEQARALITGGADLLLLETSQDMLNVKAGFIGIRQAKTLPLMVSGTIEMGTTLAGQDIESFYISLEHMKPVSVG
LNCATGPEFMTDHIRTLSSLARTAVSCYPNAGLPDE--EG--QYHESPQSLAKKIKAFAEEGLNIVGGCCGTTPAHIEALADEVALLPPRTVPS--GKPH
TV-SGIDGLIYEETMRPLFVGERTNVIGSRKFKRLIAEHKFEEASEIARAQVKNGAHVIDICLADPDRDEAEDMEGFLKKAMKKVKAPFVIDSTDKTVIE
KALKYSQGKAIINSINLEEERFADILPLVKQFGGALVVGTIDEEGMAVTAAKKLAVAVRSHQLLEKYGIPASDIIFDPLVFPVGTGDEQAKETIEGIRLI
KEQLECLTILGVSNVSFGLPGREILNAVFLYHATQAGLDYAIVNTEKLERFASIMAEKLLFTDDKTLASFTDFYRGKKKAD-----KQPKTS--LSLEER
LAEYVIEGTKEGLIPDLEQALKKFATPLDVVNGPLMDGMAEVGRLFNNNELIVAEVLQSAEVMKAAVSFLEQYMEKK-DDSGKGKIILATVKGDVHDIGK
NLVDIILSNNGYKVVDLGIKVTPQELIEAIRKENPDIIGLSGLLVKSAQQMVVTAKDLDKADISIPIMVGGAALSRKFTNKIGPVLYAKDAMDGLSLANQ
LR-
>tr|E0I542|E0I542_9BACL Methionine synthase OX=717606 OS=Paenibacillus curdlanolyticus YK9. GN=PaecuDRAFT_0764 PE=3 SV=1
-------MQE-RILIMDGAMGTMIQQADLTAAGCNEILVLTRPDVIQSIHEQYLEAGADILETNTFGSTSVVLQEDIKARELNLAAAKLAVDAAIKPRYV
AGAMGPTTKTLSVTGGVTFDELVDSYYEQAVALIEGKVDALLLETSQDTLNVKAGSIGIKRAVELPIMISGTIEMGTTLAGQTIESFYLSLEHLKPVSIG
LNCATGPEFMRDHIRTLSEIAASAISCYPNAGLPDE--NG--QYHETPDSLAAKMAGFAESGLNVAGGCCGTTPAHIRAMADVMARFEPRRKMG--EHLP
AV-TGIDTVYIEDANRPIMVGERTNISGSLKFKRLIKEGSFDEASEIARSQVKNGAQVIDINLQDTDVDEEYAVHQFIPQVVKKIKAPLMLDSTYDHIIE
LGLKYSQGKAIINSINLEESKFEKIIPLIHQYGASVVCILIDERGQAVSREAKVEVADRAYDLLNKYGVTPDDIIFDPNMFPVGSGDPQAVETIEGIRLI
KQKYRVKTILGLSNISFGLPGREVLNSVYLYECTKAGLDYAIVNSEKLERYASILAEDLIFTNDETLALFVAAFREKKVVK-----KEKTST--LTLEER
LASYIVEGTKEGLIPDLDEALKTY-APLAIINGPLMAGMEEVGRLFNGNELIVAEVLQSAEVMKASVAHLEQFMEKE-ESSVKGKIILATVKGDVHDIGK
NLVEIILSNNGYKIINLGIKVPPEQLIEAYRKEKADAIGLSGLLVKSAQQMVVTAQDLRSAGIDAPILVGGAALTRKFTKRIGLVLYAKDAMDGLDIANK
LV-
>tr|Q5L229|Q5L229_GEOKA 5-methyltetrahydrofolate--homocysteine S-methyltransferase OX=235909 OS=Geobacillus kaustophilus (strain HTA426). GN= PE=3 SV=1
--TLEQQLQR-KILVIDGAMGTMIQSANLSAAGCNEYLTLTAPHVIRRIHEAYLEAGADIIETNTFGATRIVLDEGLLALELNIEAAKLAKQTAESPRFV
AGSMGPTTKTLSVTGGATFEELVAAYEEQARGLLLGGVDLLLLETCQDTLNVKAGFLGISKARRVPLMISGTIEMGTTLAGQAIDAFFISVRHMKPIAVG
LNCATGPEFMTDHLRTLASLADTAVSCYPNAGLPDE--EG--HYHETPNMLAEKIRRFAEKGINIVGGCCGTTPDHIRAIAEAVRDLPPRAIPS--SDVH
AV-SGIEALIYDETMRPLFVGERTNVIGSRKFKRLIAEGKYEEAAEIARAQVKNGAHVIDICLADPDRDELHDMEQFVREVVKKVKVPLVIDSTDERVIE
RALTYSQGKAIINSINLEEERFAKVVPLLHQYGAAVVVGTIDEQGMAVTAERKLEIALRSYDLLNRYGVPERDIIFDPLVFPVGTGDEQAKETIEGIRLI
KERLHCLTMLGISNVSFGLPGREVLNSVFLYHCTQAGLDYAIVNTEKLERFASIMAEALLFTNDETLNAFIEFYRSKITAA-----KPAQTN--LSLEER
LARYVIEGSKDGLIPDLEKALETYSDPLSIINGPLMAGMDEVGRLFNNNQLIVAEVLQSAEVMKAAVAFLEPYMEKK-EGSTKGKVILATVKGDVHDIGK
NLVDIILSNNGYEVIDLGIKVAPQQLIEAVREHQPDIIGLSGLLVKSAQQMVVTAQDLRQAGISTPILVGGAALTRKFTEKIGVVLYAKDAMDGLALANQ
IQ-
>tr|F8CZT4|F8CZT4_GEOTC Methionine synthase OX=634956 OS=Geobacillus thermoglucosidasius (strain C56-YS93). GN= PE=3 SV=1
--TLQQQLEK-KILIIDGAMGTMIQNAQLSADGCNEYLTLTAPHVIKHIHEAYLQAGADIIETNTFGATSIVLDEDLLALELNIEAAKLARKAADAPRFV
AGSMGPTTKTLSVTGGVTFEQLAAAYEEQARGLLLGGVDLLLLETCQDTLNVKAGFIGIMKAKKVPIMISGTIEMGTTLAGQTIESFFISVQHMKPFAVG
LNCATGPEFMTDHLRTLASLADTAVSCYPNAGLPDE--EG--CYHETPEMLAKKIQRFAEKGINIVGGCCGTTPEHIRAIAEAVRGIPPRPIPA--SDVH
AV-SGIDPLIYDETMRPLFVGERTNVIGSRKFKRLIAEGKYEEAAEIARAQVKNGAHVIDICLADPDRNEQEDMEKFIQQVIKKVKVPLVIDSTDERVIE
CALTYSQGKAIINSINLEEERFAKVVPLLHKYGAAVVVGTIDEQGMAIGAERKLEIALRSYDLLNKYGVSPRDIIFDPLVFPVGTGDEQAKETIEGIRLI
KERLQCLTMLGISNVSFGLPGREILNSVFLYHCTQAGLDYAIVNTEKLERFASILAEELLFTNDETLNTFIQFYRNKMKEP-----KKAKTE--LSLEER
LANYVVEGTKDGLFADLEQALQTYADPLDIINGPLMAGMDEVGRLFNDNQLIVAEVLQSAEVMKAAVAFLEPYMEKK-ESSTKGKVLLATVKGDVHDIGK
NLVDIILSNNGFHVIDLGIKVTPQKLIEAIQAEKPDIIGLSGLLVKSAQQMVVTAQDLRQAGISIPILVGGAALTRKFTEKIGIVLYAKDAMEGLALANQ
LQ-
>tr|J7WGV5|J7WGV5_BACCE Methionine synthase OX=718220 OS=Bacillus cereus IS075. GN= PE=3 SV=1
--CIEEKLQN-NILLLDGAMGTMIQQEDLTAEGCNEYLVETRPDVILKIHKAYIEAGADIIETNTFGATNIVLSDELLDEELNEKAARLAKQAVEE-IYV
AGAMGPTTKAISVTGGVTFEELIEAYTRQARGLLKGEVDVLLVETSQDMRNVKAAYIGIQAATVVPIMISGTIEMGTTLAGQTIEAFYLSVEHMKPLSVG
LNCATGPEFMRDHIRSLSDLSECYISCYPNAGLPDE--DG--HYHESPSSLAEKVKRFAEEGVNIIGGCCGTTPEHIKAMKSALTSLKPREQQE--RAGH
GV-SGLEALQYDDSMRPLFVGERTNVIGSRKFKRLVAEGKFEEAAEIARAQVKKNAHIIDICMADPDRDEIEDMENFLAEVTKVLKVPIMIDSTDEHVME
RALTYIQGKAVINSINLEEERFEKVTPLLRKYGAAIVVGTIDEDGMAVSAERKLEIAKRSYELLTKYGIRPSDIIFDALVFPVGTGDEEAAATIEGIRLI
KEALECLTILGVSNISFGLPGREVLNSVFLYHATKAGLDYAIVNTEKLERYASILADALLFTTQETLEKFTNFYRVAKKKD-----VVVQET--LTLDER
LANYIVEGTKQGLHEDLSLALTEGRKPLDIINGPLMTGMDEVGRLFNNNELIVAEVLQSAESMKAAVSYLEPHMESS-DSAKKGKVLLATVKGDVHDIGK
NLVEIILANNGYEIINLGINVRSDRIVQEVQEKKPDIIGLSGLLVKSAQQMVTTAEDLKAADIDIPIVVGGAALTRKFTDRIGLVCYASDAMTGLDIINK
LQ-
>tr|I0API8|I0API8_IGNAJ 5-methyltetrahydrofolate--homocysteine methyltransferase OX=945713 OS=Mat9-16). GN= PE=3 SV=1
--TFKKLLSE-RILLLDGAMGTMIQRHKLTEG-NNDILCLTQPEIIKSIHRAYFEAGADIVETNTFNGTPISQSDHTLVYEINFEAARIAKEVADEPRFV
AGALGPTNKTLSPYRAVTFDEMVDAYYQQTKGLVDGGADILLIETIFDTLNAKAAIIAIQNYIELPLMISGTIVSGRTLSGQTVEAFYISISHANLVSVG
LNCALGAKQMRPFVEDLSNISDKFISVYPNAGLPNE--MG--GYDETPQSMASVLEDFLASGVNIVGGCCGTTPDHIKAIAEIVRHHKPRIPKSQ-EP-Y
LRLSGLEPVILRPDSNFMNIGERTNVAGSKTFARLIREEKYDEALSVARDQVEGGAQVLDVNMDEGMLDSEKAMTKFLNLLEAIAKLPIMIDSSKWSVIE
AGLKCLQGKGIVNSISLKEEVFKEHANKILSYGAAVIVMAFDEKGQADTFERKIEICKRAYDILKEVGFPPQDIIFDPNILAIATGMPEAVDYIEATRWI
KQNLLAKVSGGVSNLSFSFVVREAMHSAFLYHAIKAGMDMGIVNAGQLVVYEEIPVEDVILNRRPDATERLIEFAEKIKKQD--KVHIEEDE--WRVEER
LKHALIKGITDYIDEDIAEALKKYSAPLEIIEGPLMAGMNVVGDLFGAGKMFLPQVVKSARVMKKAVAILEPFIAKPQSSLG-GSVLLATVKGDVHDIGK
NIVGVVLGCNSYKVIDLGVMVHTEKIIQTAIDQKVDLIGLSGLITPSLDEMVYVAKEMQRRGLKIPLLIGGATTSRVTAVKDGAVIHVLDASRSVPVVSN
LL-
>tr|E4TPQ8|E4TPQ8_MARTH Methionine synthase OX=643867 OS=tractuosus). GN= PE=3 SV=1
--RFKDILKD-RILVLDGAMGTMIQNYKLTEG-NNDLLSLTQPKIIKDIHRAYLDAGADIIETNTFSGTTIAMADDMLVWELNEQSAKIAKEVTEEPRFV
AGSIGPTNKTASPFRATSFDELKIAYKLQAEALAVGGVDIFLVETVFDTLNCKSALMAIQELIEIPVMVSGTITSGRTLSGQTVGAFWNSIRHFPLLSVG
FNCALGADQLKTYLQQLARISDVAISCHPNAGLPNE--FG--EYDESPSEMSSIIKSYFDEGVNIIGGCCGTQPEHIKAIAEYAAKSQPHKIAAQ-KK-I
MRLSGLEPLSVTPEINFVNIGERTNVSGSKKFARLIREEKFEEAVDIAIDQVEGGAQIIDINMDDGMLDAVKVLPNFVNLISSIARLPFMIDSSKWEVIE
AGLKCLQGKGIVNSISLKEEDFIAKAKKIKSYGASVVVMAFDETGQADTFDRKIAVCKRCYDLLNKAEFPPEDIIFDPNILTIGTGMEEAVDFINAVQWI
KENLYAKTSGGVSNISFSFTVREAMHSAFLYHAIKAGLDMGIVNPGMLEVYDEIDVEDLLFNKRADATERLMAYAENIK-PG--EKAEKAQE--WRVNKR
LEHALIKGITEYIEEDTEESRLQAERPLDVIEGPLMDGMNVVGDLFGSGKMFLPQVVKSARVMKKAVAILLPYIEAEKKSGK-GKILMATVKGDVHDIGK
NIVSVVLACNNYEIIDLGVMVPLQKILEEAEKNQVDIIGLSGLITPSLDEMIYVVEEMEKRGLKTPVMIGGATTSRITAVKSGPVIHVNDASRSVTVAGK
LL-
>tr|H9UGF0|H9UGF0_SPIAZ 5-methyltetrahydrofolate--homocysteine methyltransferase OX=889378 OS=Spirochaeta africana (strain ATCC 700263 / DSM 8902 / Z-7692). GN= PE=3 SV=1
--ALEALIQE-RIVYLDGAMGTMIQNCKLQEG-NNDLLLLTRPDIIREIHTEFLDAGADILETNTFNSTSVSQADGTLVYELNRAGAALARAAADQTHFV
AGVLGPTSKTLSPFRAITFPELAESYREAVGGLIDGGADLILIETIFDTLNAKAAIYACKQEYELPIMISGTITSGRTLSGQTVEAFYNSICHAEPFSVG
LNCALGADLLKRYVSDLSRVADQPVSTHPNAGLPNE--FG--EYDHSPEFMARIMGEFAAEGVNIIGGCCGTTPEHLRQIVAATGGHAPRAIPEH-KQ-Q
LSLSGLEPLVNTPDLGFINVGERTNVTGSRKFLRLIRDKQYEEALEVARDQVEGGAQIIDINMDEAMLESADEMRTFLNLVGAISRIPIMVDSSKWSVIE
AGLQCIQGKGVVNSISMKEAEFLEHARLVRLYGAAAIVMAFDEKGQADTLERRVEICRRAYKLLEKLDFPPEDIIFDLNIFAIGTGIEEAVDFIEAARII
RREMLVSISGGVSNVSFSFAVREAIHTVFLYHAVKAGMNMGIVNPGQLEVYDDIQVEDLVMNRREDATERLLELAESIQSGGKSRVKDLS----WRVGKR
LEHALVKGITAWVEEDTEEARQQL-QALEVIEGPLMDGMNVVGDLFGSGKMFLPQVVKSARVMKMAVAYLLPYIEAEKKQQAKGKILMATVKGDVHDIGK
NIVGVVLGCNNYEIVDLGVMVECEDILAAAREHKVDVIGLSGLITPSLDEMVHVASEMERQGFELPLMIGGATTSKITAVKHAPIAHVKDASLAVNIVSR
MI-
>tr|F8EMU3|F8EMU3_RUNSL Methionine synthase OX=761193 OS=NCIMB 11436 / LSU 4). GN= PE=3 SV=1
--NIQEILKS-RILVLDGAMGSMIQRYTLADG-NNDLLSLTRPDVIREIHEAYLEAGADIIETNTFSGTTIAMADHMLVYELNYESARLAREACDKPRFV
AGSIGPTNRTASPFRAVTFDELVDAYYEQVQALTDGGADVMLVETIFDTLNAKAALYAIDLYKGLPIMVSGTITSGRTLSGQTTEAFLTSVSHMPLLSIG
LNCALGADLMRPYVQTLATQAPFYTSAHPNAGLPNE--MG--EYDQTPEQMAVIIDDFLQNGINIIGGCCGTTPPHIKAIAEVAAKYEPRDIPEN-DH-V
QKLSGLEPLKITKETNFVNIGERCNVTGSKKFARLIREGNYDAAIAVAREQVDTGAQVIDINMDEGMIDGVQAMTKFCNLLMAIARVPFMVDSSKWEVIE
AGLKCLQGKAIVNSISLKEEKFIQQAEKVRRYGASVVVMAFDEVGQADNYERRLEICERAYWILNKVGFPPQDIIFDPNILTVGTGMEEAVDFINATRWI
KEHLYAKVSGGVSNVSFSFPVREAIHTVFLYHAIKAGMDMGIVNAGQLGVYDDLPCEDLILNRRPDATERMLAFAETVKSKG--KEQVIDTA--WRVAKR
LEHALIKGLTEYIDQDVEEARQTVDKPLHVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKKAVAYLLPFIEEEKATTEGSKILLATVKGDVHDIGK
NIVGVVLACNNYEIIDLGVMVPTDKILAAAKEHNVDIIGLSGLITPSLDEMVGVAKEMERQGFKVPLLIGGATTSRITAVKSGPVIHVLDASRAVPVAGK
LT-
>tr|D5EM00|D5EM00_CORAD Methionine synthase OX=583355 OS=/ KCTC 12865). GN= PE=3 SV=1
--QLADLFAQ-RILFLDGAMGTMIQQHSLEEG-NNDLLSITRPDIIADIHRAFLEAGADIIETNTFSGTTIAQADGLRVRDINLASAKLARQ-VADPTFV
AGAIGPTNRTASPYRATNYDELYTAYYEQVEALVEGGVDLLLPETVFDTLNLKACLHAIEDFERLPVIVSVTITSGRTLSGQTVEACWNSIRHAKPLCVG
LNCALGADLMRPFLQELSRVADSYVHVYPNAGLPNP--LAPTGYDETPETTGSAVGGFAKDGVNLVGGCCGTTPGHIAAVVKEVSQYAPRPIPVT-TP-A
QRLSGLEALNIEADTGFINVGERTNVTGSPRFKKLIKADDFTAALAIAQSQVDKGAQIIDINFDEGMLDGEACMTRFLNLVASISRVPIMIDSSKWSVIE
AGLKCVQGKCIVNSISLKEDEFKAQAKKILRYGASVIVMAFDEKGQAANQADKVAIAERSFKILEEVGMDPQDIIFDLNILTVATGMEEAVDFIEAVREV
KQKCGARCSGGLSNISFSFPVREAMHAAFLHHACEAGLDMAIVNPGLLMDYQEMDVEDVLLNRNDEATEKLIEHAEAIKAAEK-KTADVASD--WRVEER
LSHALVKGIVAHVDADTEEARQKYARPLEVIEGPLMDGMKVVGELFGAGKMFLPQVVKSARVMKKAVAYLLPYMEAEKEGSSAGKFLIATVKGDVHDIGK
NIVAVVLACNNYEVKDLGVMVDCETILKEAEEWGADIIGLSGLITPSLDEMIFNAQEMQKRGFKQPLLIGGATTSKATAIKEQPIVRVGDASLVTEVCNN
LL-
>tr|B4D950|B4D950_9BACT Methionine synthase OX=497964 OS=Chthoniobacter flavus Ellin428. GN=CfE428DRAFT_5440 PE=3 SV=1
--ELAALLQK-RIAIIDGAMGTTIRTYGMKEN-NGDLFSLTQAAMIGDIHRRFLEAGADIIETNTFSATSIGQSEFVLAWDINFQSASQCREWADRQRFV
AGAVGPLTVSLSPFRTVTFDQVKAAYIQQVRALIAGGSDILLVETIFDSLNAKAALVAIQEVVSLPISISAAVGGETMISAQTVEAFWNAVKHVNPLSVG
LNCSLGPDLMRPFLEELSTKSDSAISCYPNAGLPNP--LS--PFDLEPEDMGRYLGDFAQSGLNIAGGCCGNTPEHIAAIARTLADLPPREPKEE-TKYP
LRLSGSQPF-TQQIGSYLMIGERTNVAGSPKFAKLIKEGKYEEAVAIARQQVENGANVIDICMDEGMIDGVAAMTRFLLLLGSVAKVPFMVDSSKWEVIE
AGLKCLQGKGIVNSISLKEDIFREHARTVLRYGAAVVVMAFDEQGQAATLADKIRICERAYRILDEVGFPPEDIIFDPNVLTVATGIEEAIDFIEATRWI
KANLHAKVSGGVSNISFSFVVREAMHSAFLFHAIGAGMDMGIVNAGMLEVYEEIQVEDVLLNRRPDATERLVDFGEKLKAAGADAAAEKKEE--WRVEAR
LSHALVKGIDTYIDTDTEEARAKFGRPLAVIEGPLMDGMGVVGDLFGAGKMFLPQVVKSARVMKKAVAYLTPFMEEEKARSQ-GKIVLATVKGDVHDIGK
NIVGVVLACNNYDVIDMGVMVPCEKILERARQEGADVIGLSGLITPSLDEMTHVAREMERTGLKLPLLIGGATTSKATAVKGGPVVHVLDASRAVPVVTS
LI-
>tr|F5XH04|F5XH04_MICPN Methionine synthase OX=1032480 OS=NBRC 101784 / NCIMB 13414 / VKM Ac-1990 / NM-1). GN= PE=3 SV=1
--ELTALMRR-RVLLLDGSMGVYIQRKGLSEG-NNDLLSITQPEVIRSIHDSYLEAGADIIETNTFSAQRISMADGMLSYELNLVSAQLARAACDAPRFV
AGALGPTNRTASPARNIDYQELVEAYLEQARGLVDGGSDLLLVETIFDTLNAKAAIFALETLRRWPVFISGTITSGRTLSGQVTEAFWNSIRHARPLAVG
FNCALGAADMRPYVAELARVADCFTFCYPNAGLPNA--FG--EYDETPEQMGAVVGAFAHDKINVAGGCCGTTPEHIAELERQVAGLAPREPIEV-AP-A
LRLSGLEPVNITDQSLFVNVGERTNITGSARFRKLIKAGDYPTALAVARQQVEVGAQVIDVNMDEGMIDGIAAMDRFTKLIASICRVPMMIDSSKWEVIE
AGLRCVQGKPIVNSISMKVESFVEHARLCRKYGAAIVVMAFDEDGQADNLERRKQICERAYRILDEVGFPAEDIIFDPNIFAVATGIEEGVDFIEATRWI
KQNLGALVSGGVSNVSFSFPVREAIHSVFLYHAIAAGMDMGIVNAGALVVYDEIEIEDVILNRRADATERLLEIAEAHNRAVD-DAAALA----WRVRER
ITHALVKGIDDFIVDDTEQMRVELKRPLEVIEGPLMDGMGVVGDLFGAGKMFLPQVVKSARVMKKAVAHLIPFIEAERK--SNGRIVMATVKGDVHDIGK
NIVGVVLQCNNYEVIDLGVMVPGQKILDTAREVGADIIGLSGLITPSLDEMVSVASEMERQGFTIPLLLGGATTSRATAVKSHPVVWVKDASRSVPTAAA
LL-
>tr|C6W4B8|C6W4B8_DYAFD Methionine synthase OX=471854 OS=Dyadobacter fermentans (strain ATCC 700827 / DSM 18053 / NS114). GN= PE=3 SV=1
--DIREILKN-RILVLDGAMGTMIQRYKLQDG-NNDLLSLTRPDIIKEIHAAYFAAGADIAETNTFSGTTIAMADGMIVYELNYESARLAREVADEPRFV
AGSIGPTNRTASPFRAISFDQLVEAYYEQVKGLTDGGCDLLLVETIFDTLNAKAALFAIDQFAGLPIMISGTITSGRTLSGQTTEAFLTSVSHLPLLSVG
LNCALGADLMRPYVQIMAKESPFYTSAHPNAGLPNE--MG--EYDETPEQMGEVIDGFLRDNVNIIGGCCGTTPDHIRVIAEIAGKHSPRPLPAS-ET-V
MKLSGLEPVKINALTNFVNIGERCNVTGSKKFARLIRESKYDEALSIAREQVESGAQVIDVNLDEGMIDGVEAMKTFVNLIASISKVPLMIDSSKWEVIE
SGLKCVQGKSIVNSISLKEEKFKESARTVLRYGAATVVMAFDEKGQADNYERRIEICERAYRILDEVGFPAEDIIFDPNILTVATGMEEAVDFINSVRWI
KENLHAKVSGGVSNVSFSFPVREAIHTAFLYHAIKAGMDMGIVNAGQIGIYDEIPVEDVLLNRRADATERLVTYAETVKDKG--KSQSPDLS--WRVKER
ISHALVKGIADYVDEDTEECRLLFDRPLEVIEGPLMDGMSIVGDLFGEGKMFLPQVVKSARVMKKAVAYLQPFIEAEKDSA--GKILLATVKGDVHDIGK
NIVGVVLGCNNYEIIDLGVMVPTDKILAAAQEHNVDIIGLSGLITPSLDEMVGVAKEMERRSMKMPLLIGGATTSRITAVKSGPVIHVLDASRSVPVAGK
LI-
>tr|I4EXA8|I4EXA8_MODMB B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase OX=1144889 OS=Modestobacter marinus (strain BC501). GN= PE=3 SV=1
--ALTAQLAQ-RILVLDGAMGTAIQRDRPDEG-NNDLLSITAPGIITAIHREYLEAGADLIETNTFNATRISLSDGMLAYELNVASARLARAECDAPRYV
VGAIGPTSRTASPARNVSYDELVAAYLEQAGGLVDGGSDVLLIETIFDTLNAKAAVFALETLRRWPVMISGTITSGRTLSGQVTEAFWHSVRHAQPLLVG
LNCALGAKEMRPYIAEISRVADTFVSCYPNAGLPNA--FG--EYDEAPEETAAILEEFAGAGVNLVGGCCGTTPAHIAAIARAVEGRAPRTPVEV-RP-A
LRLSGLEPVTIDEDSLFVNVGERTNITGSARFRNLIKAGDYPAALAVARQQVEAGAQVIDVNMDEGMIDGVAAMDRFTKLIASISRVPTMIDSSKWEVIE
AGLKNVQGKAIVNSISLKEEEFLAHARLCRKYGAAVVVMAFDEDGQGDTLQRRTQICRRAYDLLDQVGFPAEEIIFDPNIFAVATGIEEGLDFIEATRWI
KQNLGALVSGGVSNVSFSFPVREAIHSVFLYHAIAAGLDMAIVNAGQLEVYSEVPIEDVVLNRRPDSTERLLEIAADFAGDSVKEAATEE----WRVDER
ITHALVKGIDAFVEDDTEELRQQIGRPIEVIEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKKAVAHLIPFIEAEKQERSNGKVVMATAKGDVHDIGK
NIVGVVLQCNNYDVVDLGVMVPAQRILDTAKAEGADIIGLSGLITPSLDEMVNLATEMERQGFEVPLLVGGATTSRATAVKHGPVVWVKDASRSVPVVAA
LL-
>tr|F8F2E4|F8F2E4_SPICH Methionine synthase OX=744872 OS=Spirochaeta caldaria (strain ATCC 51460 / DSM 7334 / H1). GN= PE=3 SV=1
--Q----LDK-RILLLDGAMGTMIQKFGLTEG-CNDILCITKPSVIASIHQAYLRAGSDIIETNSFNANAISLADNLYAFEISRAAARVARESADLPRFV
AGVLGPTSKTASPARAVTWEELEAAYYDNARGLLAGGADILMIETIFDTLNAKAAIAAIQRLSEVPIMISGTIVAGRTLSGQTVEAFCVSVMHAKPWSIG
LNCSLGAERLYPHVAALSEIAPCLVSAHPNAGLPNR--FG--QYDESAQTMAGFIEAFLRDGVNIVGGCCGSTPAHIAEIARVTMNYQPRVIPAP-RK-T
V-LAGLEPLVVDPAIGFIDVGERTNVAGSRKFLRLIKEERYDEALSIARDMVEAGASIIDVCMDDALLDAPRAMQKFLNLALAIARLPVMVDSSRWEAIE
AGLKCLQGKGIVNSISLKEEAFLRKSRIARRMGAAVVVMLFDERGQADSYERKVEVAQRSYQLLQ-DGMKGEDIIFDPNVLAIATGIPEALDFIKACRWI
RANCGAKISGGVSNLSFSFLVREAMHAVFLKYAIEAGLTMAIVNPAGLVPYDELEAEDVVLARRSDAAERLLALALELKEA-H-GTVGSD-SSVWRVEER
LQYALVKGIEDYIEPDILEARSRYQRSLDVIEGPLMKGMNEVGDRFGAGKMFLPQVIRSARVMKKAVAVLEPFIQEEKLRLT-SKIIMATVKGDVHDIGK
NIVGVVLGCNGYEVHDLGVMIPPDEIAEAIIREQADLVGLSGLITPSLDEMVHTARELERRGVSIPLLIGGATTSEATALRSGPVVYVKDASRAAAVVRA
LL-
>tr|D2S6D2|D2S6D2_GEOOG Methionine synthase OX=526225 OS=G-20). GN= PE=3 SV=1
--ELTAVLGQ-RILVLDGAMGTAIQRDRPDEG-NNDLLSITRPEIIAGIHREYLEAGADLVETNTFNATAISLRDGMLAYEINVAAARLARAEADAPRYV
AGALGPTSRTASPARNVTFDELALAYLEQADGLVDGGVDVLLIETVFDTLNAKAAIYALETLRRWPVMVSGTITSGRTLSGQVTEAFWHSIRHVRPLLVG
LNCALGAAEMRPYLAELSRVADTYVSCYPNAGLPNA--FG--EYDESPEETAAVLAEFADAGVNTVGGCCGTTPAHIAVIAATVEGRAPRTPPRV-RP-A
LRLSGLEPLVVDEDSLFVNVGERTNITGSARFRNLIRAGDYPTALAVARQQVEAGAQVIDVNMDEGMIDGVEAMDRFLKLVAAICRVPVMVDSSKWEVIE
AGLKCVQGKSIVNSISLKEEEFVQQARLCRKHGAAVVVMAFDEQGQADSLQRRQEICRRAYDILEQVGFPAEDVIFDPNVFAVATGIEEGLDFIEATRWI
KQHLGALVSGGVSNVSFSFRVREAIHAVFLFHAIAAGMNMGIVNAGALEVYDEVPIEDVVLARRPDATERLLEIAAEYAGDAQKEVASEE----WRVEER
IAHALVKGIDGFVEADTEELRAQIGRPIEVIEGPLMGGMNVVGDLFGAGKMFLPQVVKSARVMKKAVAYLVPFIEAEKQERSNGKVVMATVKGDVHDIGK
NIVGVVLQCNNYDVVDLGVMVPAQKVLDTAKQEGADVIGLSGLITPSLDEMSNLAAEMERQGFDIPLLIGGATTSRATAVKHGPVIWVKDASRSVPVVAA
LL-
>tr|E2S9W9|E2S9W9_9ACTO Methionine synthase OX=585531 OS=Aeromicrobium marinum DSM 15272. GN= PE=3 SV=1
--DLTRMLRE-RILVLDGAMGTAIQRDRPDEG-NNDLLTLTQPEIIAGIHREYLEAGADMIETNTFNANCISLSDGMLAYEFNLESARLARRECDAPRYV
AGALGPTSRTASPARNVTYDELVDAYKEATRGLLDGGSDVIIIETIFDTLNAKAAIFAVETVRRWPVIISGTITSGRTLSGQVTEAFWHSIRHAKPLLVG
LNCALGAQEMRPYIAEMARVADTFVSCYPNAGLPNA--FG--EYDEEPDQTAAIVSEFADAGVNMVGGCCGTTPAHIASIAREVDGSTPRPVPDT-TP-A
LRLSGLEPVTVVEDTLFVNVGERTNITGSARFRNLIKAGDYTTALAVARQQVEAGAQVIDVNMDEGMIDGVEAMDRFMKLVATICRVPTMIDSSKWEVIE
AGLKCVQGKSIVNSISMKEEKFVREARLCRKYGAAVVVMAFDEEGQADNLERRRQICERAYRILDEVGFPAEDIIFDPNVFAVATGIEEGVDFIEATRWI
KQNLGALVSGGVSNVSFSFPVREAIHAVFLYHAIGAGMDMGIVNAGALEVYDEVPIEDVILNRREDSTERLLDIAADFAGDSVKEVATEE----WRVGER
ITHALVKGIDEFAESDTEELRAEIGRPIEVIEGPLMAGMNVVGDLFGEGKMFLPQVVKSARVMKKAVAYLIPFIEAEKQERSNGKVIMATVKGDVHDIGK
NIVGVVLQCNNYDVVDLGVMVPAQKILDAAKAEGADVIGLSGLITPSLDEMVNFAVEMERQGFEIPLMIGGATTSRATAVKHGPVIWVKDASRSVPVVAA
LL-
>tr|A3TL58|A3TL58_9MICO MetH OX=313589 OS=Janibacter sp. HTCC2649. GN=JNB_03055 PE=3 SV=1
--ALTAALTE-RVLVLDGAMGTMIQREGLSEG-NNDLLSLTNPSIIEGIHRAYLLAGADLVETNTFNAQRISLADDMIAYEMNLEAARLARRACDEPRWV
MGALGPTTRTASPARNVSFDQLVEAYLEQARGLVDGGADALIIETIFDTLNAKAAIFAVETLRRWPVIISGTITSGRTLSGQVTEAFWNSVRHARPLVVG
LNCALGPDELRPYIAELSRIAGCFVSAYPNAGLPNA--FG--EYDETPDQMASVVGEFATSGVNILGGCCGTTPEHIEAIAEAAAKGNPRVPSEV-PG-A
LRLSGLEPLTVDESSLFVNVGERTNITGSARFRRLIKEEDYPAALSVARQQVEAGAQVIDINMDEGMIDGVAAMDRFVKLIGSICRVPLMIDSSKWEVIE
AGLKCSQGKPIVNSISMKVEPFLEHARLCHKYGAAVVVMAFDEEGQADSLERRKVICQRAYDLLQEVGMDPHDIIFDPNIFAVATGIEEGTDFIEATRWI
KENLGALVSGGVSNVSFSFPVREAIHAVFLYNAIQAGMDMGIVNAGALVVLDDVDIEDVVLNRRPDSTERLVEIADRFNNTAP-EVTEAE----WRVRER
ITHSLVKGIDDFVVEDTELLRQEIGKPIEVIEGPLMDGMGVVGDLFGAGKMFLPQVVKSARVMKKAVAHLIPYIEAEKEQNSKGLIVMATVKGDVHDIGK
NIVGVVLQCNNYDVIDLGVMVPTQKILDTAKEKGADIIGLSGLITPSLDEMVRVAQEMERQGFTIPLLIGGATTSRATAVKSGPVVWVKDASRSVPVASQ
LL-
>tr|E6SA58|E6SA58_INTC7 Methionine synthase (B12-dependent) OX=710696 OS=NBRC 12989 / 7 KIP). GN= PE=3 SV=1
--ILSATLRE-RIMVLDGAMGTAIQRDRPDEG-NNDLLTLTQPELVAQIHRDYLEAGADVIETNTFNANAISLGDGMLAYEINWEAARLARREADAPRWV
AGAIGPTTRTASPARNVTFDQLVDAYSEAARGLLDGGADLLLVETIFDTLNAKAAIFAVESVRRWPVIVSGTITSGRTLSGQVTEAFWNSVRHVRPLAIG
LNCALGAKELRPYISELARVADCFVSCYPNAGLPNA--FG--EYDEAPDETAEVISEFAAAGVNIVGGCCGTTPEHIAAIAKAVDGKPGHTVAPP-TT-A
MRLSGLEPFTINEDSLFVNVGERTNITGSARFRTLIKDGDYDTALSVAAQQVENGAQVIDVNMDEGMIDGVAAMDRFLKLVASISRVPVMIDSSKWEVIE
AGLKCVQGKAIVNSISLKEESFIEHARLVRKYGAAAVVMAFDEDGQADSLESRTQICARAYRILEEVGFPAEDIIFDPNVFAVATGIEEGRDFIEATRWI
KENLGAKVSGGISNVSFSFPVREAIHAVFLYHAIAAGLDMGIVNAGALAVYDEIDVEDVVLNRRPDAAERLLEVAERYNRAGPDAVTEDE----WRVRER
ITHSLVKGVDAHIEDDTELLRAEIGQPIEVIEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKKAVAYLIPYIEEEKAKDTNGTIVMATVKGDVHDIGK
NIVGVVLQCNNYEVIDLGVMVPAQKILDAAREHEADLIGLSGLITPSLDEMVGFAAEMQRQGFDIPLLIGGATTSRATAVKDGPVVWVKDASRSVPTAAA
LL-
>tr|E3BDN0|E3BDN0_9MICO Methionine synthase OX=188626 OS=Dermacoccus sp. Ellin185. GN= PE=3 SV=1
--ELAALMRE-RILVMDGAMGTMIQRHGLSEG-NNDLLSLTQPDIIEGIHREYLEAGADIVETNTFNAQRISLADDMFAYEFNVESAKLARTAADSPRFV
AGAIGPTNRTASPARNVSFDDLVGAYLEQARGLADGGVDLMLIETIFDTLNAKAAIFALEQLRRWPVIISGTITSGRTLSGQTGEAFWNSVRHARPLAVG
LNCALGADEMRPYVADLSRIADCFVSCYPNAGLPNA--FG--EYDETPEAMTQTVAAFAGDGVNLVGGCCGTSPDHIGAIADAVAATAPRSVPDV-AP-A
LRLSGLEPFTVDEDSLFVNVGERTNITGSARFRKLIKDGDYATALSVARQQVENGAQIIDVNMDEGMIDGVAAMDRFCKLIASICRVPVMVDSSKWEVIE
AGLKCIQGKSIVNSISMKVEPFIEHARLCKRYGAAIVVMAFDEDGQADTLERRKTITKRAYDILGDVDFPAEDIIFDPNIFAIGTGIEEGVDFIEGTRWI
KANLGALVSGGVSNVSFSFPVREAIHAVFLYHAVAAGMDMGIVNAGALVVYDEIDIEDVVLNRRADATERLLEAAEQYNSSAE-AKTE-Q----WRVRER
ITHALVKGIDDHVEADTEQMRAELKRPLEVIEGPLMDGMGVVGDLFGAGKMFLPQVVKSARVMKKAVAYLIPFIEAEKEKQTNGTVVLATVKGDVHDIGK
NIVGVVLQCNNYEVIDLGVMVAPQKILDAAREHDADIIGLSGLITPSLDEMVHLASEMQRQGFTQPLLIGGATTSRATAVKDEPVVWVKDASRSVPVVAA
LL-
>tr|D5SPE9|D5SPE9_PLAL2 Methionine synthase OX=521674 OS=290). GN= PE=3 SV=1
--LFESLLDD-RILILDGAMGSMIHRFEPTEN-ASDVLVLTQPQMIQSIHRQYLEAGADIIETNTFGATELMLDEHLLTHEMNIAAATLARDVCDEPRFV
AGSIGPTKFQLSAYRPVTFEQLAASYAGQVRALLDGGVDLLLPETSFDTLNMKACLYAIEQVVRIPVMVSGTIF-GVTLTGQTMEAFWAAVSHNPMTSVG
LNCALGPKQMRQYVETLANTATRYISCYPNAGMPDG--MG--GFDSTPSEFSGVIREFAENGVNIVGGCCGTTPEFIHAVANVVKGVAPRKVPHE-NH-W
SVYSGSDVLKIAPNRSFLMIGERTNVTGSKKFARLIREKKYEEALTIAAQQVENGANMIDVNMDEGLLDSKAEMVHFLNLISDISKVPVMVDSSKFDVIE
AGLKCLSGKGVVNSISLKEEKFLEHAGIIRKYGAAVVVMAFDEEGQAADQVNKVRICQRAYKLLEKAGFPPEDIIFDCNILTVGTGMEEAVEFIEAVREI
KATCYARTSGGVSNVSFSFHVREAMNAAFLYHAINAGLDMGIVNAGQLAVYDEIEVEDVLLNRRPDATERLIAYSEELKARE--TRTDDSGPVAWRVEER
LKHALLKGIADFIDEDTEEARLKYSRPLNVIQGPLMDGMNVVGKLFGEGKMFLPQVVKSARVMKKSVAYLQPFMEAEKASSARGKILIATVKGDVHDIGK
NIVAVVLRCNNFEVLDLGVMVPCDKILDTAIAEGCQIIGLSGLITPSLDEMTTVAKEMERRGFKIPLLIGGATTSAKTAVKSAPTVHIVDASLSVPVVEN
LL-
>tr|D2QKR8|D2QKR8_SPILD Methionine synthase OX=504472 OS=Spirosoma linguale (strain ATCC 33905 / DSM 74 / LMG 10896). GN= PE=3 SV=1
--TIYELLHE-RILVLDGAMGTMIQRYNLTDG-NNDLLSLTKPEIIQAIHKQYLEAGADIIETNTFSGTSIAMADRMLAYELNYESARIAKEVAVEPRFV
AGAMGPTNRTASPYRAVTFDELVNAYYEQVSGLVDGGADLLLVETIFDTLNAKAAMFAIDKYKTLPIMISGTITSGRTLSGQTTEAFLYSVSHLPLLSVG
LNCALGAQLMRPYIQTLAKEAPFFTSAYPNAGLPNE--FG--EYDETPDMMALQIEDFVKSNVNIVGGCCGSTPDHIRAIADVAAKYPPRQLPQP-EP-Y
QKLSGLEPLKITEQTNFLNVGERTNVTGSKKFARLIKEGNFDEALSIARGQVEGGAQVIDINMDEGMLDSVEAMKTFLNLIAAIARVPIMVDSSKWEVIE
AGLKCVQGKAIVNSISLKEEAFIERANLVKRYGAAAVVMAFDENGQADSYERRIEICERAYRILDKVQFAPQDIIFDPNILTVATGIEEAVDFINATRWI
KQNLLAKVSGGVSNISFSFVVREAMHSAFLYHAIRAGLDMGIVNAGQLEVYDSIPCEDVLLNRRDDATERLVEFAETVKAKG--KAIVQDES--WRVRER
LKHALIKGITDYIDQDVEEIRQQVERPLHVIEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKKAVAYLTPFIEAEKGSNA-GKILLATVKGDVHDIGK
NIVGVVLGCNNYEIIDLGVMVPTQKILDAAREHNVDIIGLSGLITPSLDEMVGVAKEMERQGFKLPLLIGGATTSRITAVKSGPVVHVLDASRSVPVAGR
LV-
>tr|I2GPM3|I2GPM3_9BACT Methionine synthase OX=1185876 OS=Fibrisoma limi BUZ 3. GN= PE=3 SV=1
--SITDLLQQ-RILVLDGAMGTMIQRYQLTEG-NNDLLSITQPHIIQEIHRQYLDAGADIIETNTFSGTWVAQADYMLVYELNYQSAKIAKEVADDPRFV
AGAMGPTTRLASPYRAITFDQLVEAFYTQVAGLVEGGADVLLVETITDTLNAKAALFAIDKYRKLPIMISGTITSGRTLSGQTTEAFLYSVSHLPLLSIG
LNCAMGAELLRPYVQTLAKESPFFTSAYPNAGLPNE--MG--EYDQSPDEMAAQIEGFVQDGVNIVGGCCGSTPDHIRAIAQAVAKYAPRPKPEQ-KP-Y
QKLSGLEPLKITEQTNFVNIGERTNVTGSKAFARMIKAGDYDAALSVARQQVENGAQVIDINMDEGMLDSVEAMTTFLNLIAAIARVPIMIDSSKWEVIE
AGLKCVQGKAIVNSISLKEEAFIERAQLVRRYGAAAVVMAFDEVGQADSYERRIEICERAYRILDKVGFAPQDIIFDPNILTVATGIEEAVDFINATRWI
KENLLAKVSGGVSNISFSFPVREAMHSAFLYHAIKAGLDMGIVNAGQLAVYDEIPCEDVLLNRRPDATERLVEFAETVKAKG--KEVVQDNA--WRAAER
LKHALIKGITDYIDQDVEEARLQYDRPLQVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKKAVAYLTPFIEAEKGS-A-GKILLATVKGDVHDIGK
NIVGVVLGCNNYEIIDLGVMVPTQKILDEARRHNVDIIGLSGLITPSLDEMVGVAKEMERQGFTIPLLIGGATTSRITAVKSGPVIHVLDASRSVPVAGR
LV-
>tr|I0KGX9|I0KGX9_9BACT Methionine synthase OX=1166018 OS=Fibrella aestuarina BUZ 2. GN=FAES_5383 PE=3 SV=1
--QLTDLLQQ-RILILDGAMGTMIQRYNLSEG-NNDLLSLTRPDIIAEIHRQYFEAGSDIVETNTFSGTSIAMADHMLVYELNYESARIARAIADEPRFV
AGAMGPTNRTASPYRAVTFDELVDAYYEQVRGLVDGGSDILLVETIFDTLNAKAALFAIDRYKPLPIMVSGTITSGRTLSGQTTEAFLYSVSHLPLLSVG
LNCALGAELLRPYVQTLANESPFYTSAYPNAGLPNE--MG--EYDQSPDEMAAQIESFAKDGVNIVGGCCGSTPDHIRAIAGAMAKYQPRPKPTP-EP-Y
QKLSGLEPLKITEQTNFVNVGERTNVTGSKAFARLIKAGDYEAALAVARQQVENGAQVIDVNMDEGMLDSAEVMTTYLNLIAAIARVPVMIDSSKWEVIE
AGLKCVQGKAIVNSISLKEQAFIERAQLVKRYGAAVVVMAFDEDGQADSYERRIQICERAYRILDQVKFAPQDIIFDPNILTVATGIDEAVDFINATRWI
KENLLAKVSGGVSNISFSFPVREAMHSAFLYHAIRAGMDMGIVNAGQLAIYDDIPVEDVLLNRRDDATERLVTFADTVKAKG--KEVVVDEA--WRVAER
LKYALIKGITDFIDEDVEEARLQAERPLHVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKKAVAHLTPYIEAEKVAGA-GKILLATVKGDVHDIGK
NIVGVVLGCNNYEIIDLGVMVPTQKILDAAREHNVDIIGLSGLITPSLDEMVGVAKEMERQGFTIPLLIGGATTSRITAVKSGPVIHVLDASRSVPVAGR
LV-
>tr|Q9RVQ6|Q9RVQ6_DEIRA 5-methyltetrahydrofolate--homocysteine methyltransferase OX=243230 OS=LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422). GN= PE=3 SV=1
--TITEAARQ-RILILDGAWGTQLQRANLTEG-NFDLLQLTKPDVIRAVHRAYFEAGADIASTNTFNSTTISQADGTLAYAMNREGARLAREVADEKRWV
AGSVGPTNRTATPFRNVTYDDLVAAYSEAITGLMEGGADLLLIETVFDTLNAKAALFAAQDVRELPVMLSGTITSGRTLSGQTPEAFAVSTEHAGLFSLG
LNCALGADLLRPHLRAIAANTEALVSVHPNAGLPNA--FG--EYDETPEHTAAVLADFAREGVNIVGGCCGTTPEHIKAIAEAVKDIPPRQALQL-PP-Y
LRLSGLEAFTLTPETNFVNVGERTNVTGSPKFSKAILAGDYDAGLKIARQQVTNGAQIVDINFDEGMLDGEGAMVKFLNLLAGISRVPLMLDSSKWEILE
AGLRRVQGKAVVNSISLKEARFLERARLLRRYGAAAVVMAFDEQGQADNLARRREILGRAYRLLEQADFPPQDIIFDPNVLTVATGIEEALDFIEATRWI
KENLAAKVSGGISNVSFSFHVREAMHAVFLYHAIRAGLDMGIVNAGMLAVYEDIEVEDVILARRPDATERLLTLADRYKDI---RESAAQSA--WRVQER
LRHALVQGVADHVDEDAEAAYQELGSPLAVIEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKKAVAYLTPYLEAEKASSSKGKVLLATVKGDVHDIGK
NIVGVVLACNGYQVTDLGVMVPGEKILDEAERLGADVIGLSGLITPSLDEMVNVAREMTRRGVKTPLLIGGATTSRATAVKDGTVVHVLDASRAVTVTND
LL-
>tr|H0IN76|H0IN76_MYCAB B12-dependent methionine synthase OX=1091046 OS=Mycobacterium abscessus subsp. bolletii BD. GN=MBOL_19390 PE=3 SV=1
--ALTAALEQ-RILVIDGAMGTAIQRDRPDEG-NNDLLTLTQPHIIEGIHREYLEAGADILETNTFNANAVSLSDGMLSYELNYAGAALARVAADEPRYV
AGALGPTTRTASPARNVSYDQLVAAYLEAAHGLVDGGADIILVETIFDSLNAKAAVFAIETLRRWPIIISGTITSGRTLSGQVTEAFWNAIRHARPIAVG
LNCALGAPEMRPYIAEMSRIADTFVSCYPNAGLPNA--FG--EYDESPEHQAGYLAEFAEAGVNLVGGCCGTAPAHIAEIAKVVEGVKPRDVPSI-DV-A
TRLSGLEPLNITDDSLFVNIGERTNITGSARFRNLIKAEDYDTALSVALQQVEVGAQVIDINMDEGMIDGVAAMDRFTKLIAAISRVPVMIDSSKWEVIE
AGLKNVQGKPIVNSISMKEEKFIREARLCRKYGAAVVVMAFDEKGQADNLERRKEICGRAYRILEEVGFPAEDIIFDPNCFALATGIEEGIDFIEACAWI
KENLGVHISGGISNVSFSFPVREAIHAVFLFHAIKAGLDMGIVNAGALVPYDSIDIEDVVLNRRADAAERLLEIAERFNSTGD-DRAAQE----WRVRER
ITHALVKGIDAHVDDDTEELRAEIGRPIEVIEGPLMDGMNVVGDLFGSGKMFLPQVVKSARVMKKAVAYLLPFIEAEKEKDTNGTIVMATVKGDVHDIGK
NIVGVVLQCNNFEVIDLGVMVPAQKILDAAKEHDADIIGLSGLITPSLDEMANFAVEMEREGLEIPLLIGGATTSRATAVKKGPVVWVKDASRSVPVAAA
LL-
>tr|B2UNQ8|B2UNQ8_AKKM8 Methionine synthase OX=349741 OS=Akkermansia muciniphila (strain ATCC BAA-835). GN= PE=3 SV=1
--YLKDQLRK-RVVILDGAMGTNIQKFRLGEN-NNDLLVLTRPDIILDIHRRFLDTGTDILETCTFGATSIGQHDELLVRELNLAAAALARQACDEPRLV
AGSIGPMPVTCSPFRAVNFRQLRQAYRDQVLALLEGGVDMLLVETIFDTLNAKAALFAIEEISSVPVMVSVTLTAGRTLSGQTIEAFWNSIRHVRPFSVG
INCALGPDLMRPFAEELSGLADCHMSIYANAGLPNP--LSPTGYDLLPADMARFMKEYAEQGLNIVGGCCGTTPEHIGAIAAAVEGMPPRVPAPQ-TP-A
LRLSGYEAYNHTREKNTLFVGERCNVAGSPKFARLIREGNYEEAVSIARQQVENGALVLDFCFDDGLIDGPQAMVRFLNLVSAIARVPFMVDSSKWEVLE
AGLQCMQGKGIVNSISLKEEEFLKKAALIKKYGAAVVVMAFDEQGQAANYEDRVRISRRAYDLLNRVQFPPEDIIFDPNVLTVGTGIAEALDFFKAAGWI
SRNLHAHISGGISNVSFAFPVREAMHSAFLYHATQQGLDMCIVNAGMLEVYDNIPIEDVLLNRRTDATERLTDYAEKLAAEGK-EKKTVQ-A--WRVAKR
LEYSLIKGITEFVDADTEEAFQELGSPLNVIEGPLMAGMKVVGQLFGDGKMFLPQVVKSARVMKQAVAWLTPYIEADS-AKA-GKAVIATVKGDVHDIGK
NIVGVVLSCNGFEMIDLGVMVHCDTILDRAEAEQADLVMLSGLITPSLEEMSHVAAEMERRGMTIPLMVGGATTSALTALKQGAVVHTEDASQVVPAAAS
LV-
>tr|B0SU32|B0SU32_LEPBP Methionine synthase OX=456481 OS=Paris). GN= PE=3 SV=1
--TLLKLLTE-RILVLDGAMGTMIQRHSLEEG-NNDVLAITRPDIIESVHLEYLEAGADIIETNTFSSNIVSQADKMAVRDLNLAAVQCAKNAVAKEVFI
AGSIGPTVKTASPFRAVTFDELVDCFYEQVSALLDGGVDLLLPETNIDTLNLKACIFAIEKVIRIPVVLSVTITSGRTLSGQTGEAFYISIKHAKPLAVG
INCALGAGEMRPYIEEISRVADCYVSCYPNAGLPNA--FG--GYDQTPDEFGGWMKNFAEAGLNIVGGCCGTTPAHIQAAKEAVTSIKPRPLREQ-PK-L
SAFAGLEPLKLTKDQGFINVGERNNVTGSPKFKKLILDGNFEEAVQVALQQVQAGANIIDINFDEALLDGEASMTKFLNLISGIARVPFMIDSSKWSVLL
AGLKCIQGKPIVNSISLKEEVFLNHARTIQRFGASAIVMAFDEQGQAATRDEKVRICKRAYDLLSKLDFDPTDIIFDPNILTVATGIEEAVDFIEATREI
KKVCGAKVSGGLSNISFSFPVREAMHSAFLYHAIQAGMDMAIVNAGMLEVYEQIPVEDVLLNRRPDATERLIDAAGSFHGEA--KVQKKDDV--WRVEER
LTHALVKGIDEFVTQDTEEARQSLAKPLDVIEGPLMNGMKVVGELFGAGKMFLPQVVKSARVMKKAVAYLMPYMEEEKRESKQAKFLIATVKGDVHDIGK
NIVGVVLACNNYEVIDLGVMVPCEKILETAKKENVAAIGLSGLITPSLDEMVYVAKEMERLEFKVPLLIGGATTSPATAVKSQPVLHVMDASRVVNVMNS
VL-
>tr|A1ZT30|A1ZT30_9BACT Methionine synthase OX=313606 OS=Microscilla marina ATCC 23134. GN=M23134_07015 PE=3 SV=1
--MIEQLLKK-RIFVLDGAMGTMIQRYKFTEG-NNDLLSITQPEAIKTIHGKFLEAGADILETNTFSATTIAMADHMLVYELNYESAKIAKEVATEPRFV
AGSIGPTNRSASPLRNITFDQLVVAYYEQAKALVEGGVDILLVETIFDTLNAKAALFAIDKYKRLPIMVSGTITAGRTLSGQTIEAFLYSVSHMPILTVG
VNCALGADLMRPYIQSLAKNAPFLVSAHPNAGLPNE--FG--EYDQTPEEMGAIIKEFLESGLNVVGGCCGTTPEHIAEITKIAAEYSPRVIPEQ-ER-L
ATYSGMEPLKVTKAINFVNIGERTNVAGSAKFRKLIKNEQYEDALAIALHQVEGGAQVIDVNMDEGMIDSEEVMTIFLNLIASIARLPIMIDSSKWTVIE
AGLKVVQGKSIVNSISLKEENFKNQANLVRRYGAAVVVMAFDEVGQADSYERRIEICERAYRILDEVKFPPEDIIFDPNILTVATGMEEAVDFINATRWI
KENLYAKVSGGVSNISFSFVIREAMHSAFLYHAIKAGLDMGIVNAGMIEVYEDIPIEDVLLNRNADATDKLITFAEQVKGKG--KVQVKDTK--WRVEER
LKHALLKGITEFIDEDTEEARLKYDRPLHVIEGPLMDGMSVVGDLFGQGKMFLPQVVKSARVMKKSVAHLMPFMEKEKEKGV-GKILMATVKGDVHDIGK
NIVGVVLGCNNYEVIDLGVMVPAQKILDTAIKEKVDVIGLSGLITPSLDEMVNVANEMERLGLDIPLLIGGATTSRITAVKKGSVIHVLDASRSVPVVSN
LL-
>tr|I4B665|I4B665_TURPD Methionine synthase (B12-dependent) OX=869212 OS=(Leptospira parva). GN= PE=3 SV=1
--EIRAALSE-RILILDGAMGTMIQRQNLTEG-NSDLLCLTRPDVITAIHREYIDAGADIIETNSFSSNSISQGDKLLVRELNLAAVKCVADAREAKIFI
AGALGPTTKTASPYRATTFDELKACFKEQTLALLEAGVDLLLPETNLDTLNVKAAIVAFEEAYRVPVSISVTITSGRTLSGQTAEAFFNSVRHANPLSIG
INCALGAKDMKPHLQSLARVSDVMISCYPNAGLPNA--FG--GYDETPAMFASDLAVFAKDGLNIAGGCCGTSPDHIREMVKRVAIEKPRSARSL-RA-P
QHLAGLEPLNVDGSTGFLMIGERTNVTGSPKFKKLILEDKFDEALDVARQQVFAGANIIDVNFDEALLDGEASMTRFLNLIASIARVPIMIDSSKWSVIQ
AGLKCVQGKGIVNSISLKEDKFLEQAKIVKEYGFAMVVMAFDEQGQAATEDDKVRICTRAYKLLEKAGVSPSDIIFDPNILTVATGIEEAVDFINATRRI
KKECGCYVSGGVSNVSFSFAVREAIHSVFLYHAIQAGLDMGIVNAGMLAVYEDIPVEDVILNRRSDATERLLAVADKYKSGGK-EQVKEDLT--WR-EER
IKHALVKGIDQFVDQDVEELRLKYQPTLRVIEGPLMGGMRVVGELFGAGKMFLPQVVKSARVMKKAVAYLLPFMEAEKASSAQTKVLMATVKGDVHDIGK
NIVGVVLACNNYDVHDMGVMVPCDKILEKAREINADVIGLSGLITPSLDEMVYVASEMKKGGFTQPLLIGGATTSAATAVKDHPVVHVPDASLVTGVLGR
LL-
>tr|E8R0S5|E8R0S5_ISOPI Methionine synthase (B12-dependent) OX=575540 OS=Isosphaera pallida (strain ATCC 43644 / DSM 9630 / IS1B). GN= PE=3 SV=1
--LLQAMAAQ-RILLLDGGMGTMIQQVPLGEG-NNDLLVMTRPEVIRSIHEAYLAAGSDIIETNTFNGTAISQAEGLIAYDLNVEAARLARAAADQPRLV
AGAIGPTSCTLSPFRPVSFDQLKEAYAEQARGLIDGGVDLILIETIFDTLNAKAALVAVEEAIRLPLMLSVTIVSGRNLSGQTVDAFWASVAHARPFSVG
INCALGAVEMRPYLAELARVADVYVSCYPNAGLPNP--LSDTGYDELPETTGAHLGEFARSGVNIVGGCCGTTPDHIAAIARAVRESPPRTLPKV-PG-R
PEYSGLETLAIRPDSGFLMIGERTNVTGSKKFAKLILAGDYQGALEVARDQVRGGANILDVNMDEAMLNGEEAMTTFLNLIATIARIPIMIDSSKWSIIE
AGLKCVQGKPIVNSISLKEEDFLEKARTVLKYGAGVVVMAFDEVGQADTVERKVEICQRAYKLLEKLNFPPQDIIFDPNILAIATGIEEAVNFIEATRII
KATCGAKISGGVSNLSFSFVVREAMHAAFLYHAIRAGMDMGIVNAGQLAIYDEIPVEDVIFNRRPDATDRLLAFAETVKGK---KQRIADDA--WRVQER
LQYALIHGIDAYVVADVEEARAHYDRPLHIIEGPLMDGMRVVGDLFGAGKMFLPQVVKSARVMKKAVAYLEPFMAAEKVMSAQGRVVLATVKGDVHDIGK
NIVGVVLGCNNYEVIDLGVMVPMERILQAAEEHQADMIGLSGLITPSLDEMVSIAAEMERRGMTIPLLIGGATTSKQTAVKSKATVHVLDASRAVNVVAS
LL-
>tr|K6FWJ8|K6FWJ8_LEPIR Methionine synthase OX=1049937 OS=Leptospira interrogans str. UI 12621. GN= PE=4 SV=1
--ELLSLLEK-QILVIDGAMGTMIQRFSLQEG-NNELLCLTRPDVIESIHLKFLEAGANIVETNTFSSNQISQGDKTLVADLNKAAVVCARNAITKPCLI
AGAIGPTTKTATPFRAVTFDDLVATFYEQARALVESGVDLLLPETNIDTLNLKAAIFAIEQVVRIPVCLSVTITSGRTLSGQTVEAFYNSIAHCNPLSVG
INCALGADEMRPYIEELARVSPCYISCYPNAGLPNA--FG--GYDQTPEEFGKYIQEFASSGLNIAGGCCGTTPEHIEAAAKAVRGKKPRILPKI-EE-V
TRLSGLEPLNITPDKGFLLVGERTNVTGSPKFKKLIIEGNFEEAVSVALQQVEAGANIIDINFDEALLDGEASMRHFLNLIAGIAKVPFMIDSSKWSVLE
EGLKCIQGKPILNSISLKEDKFLEYAKKIQRYGASAIVMAFDEQGQAATKEDKVRICKRAYDLLTKANFSPTDIIFDPNILTVATGIEEAVDFIEAVREI
KKLCGAKVSGGLSNVSFSFPVREAMHSVFLYYAIQAGMDMAIVNAGMLAVYEEIPVEDVILNRRPDATERLVEFAESVKSTGD-KTEKKEEA--WRVEER
LSHALVKGIVEYIDQDTEEARLKYGRPLTVIEGPLMDGMKIVGELFGAGKMFLPQVVKSARVMKKSVAYLLPFMEEEKNSTARPKFLIATVKGDVHDIGK
NIVGVVLACNNYEVIDLGVMVPPDKILEEAKKHNVSIIGLSGLITPSLDEMVHVASEMKRIGLEIPLLIGGATTSSATAVKDHPVVHVVDASRVVNVVNQ
LL-
>tr|Q7UKY7|Q7UKY7_RHOBA 5-methyltetrahydrofolate--homocysteine methyltransferase OX=243090 OS=Rhodopirellula baltica (strain SH1). GN= PE=3 SV=1
--QLAELIRE-RILMLDGAMGTMIQRLELDEN-FSDILCLTHPEKITEIHSKYYEAGSDIVETNSFGASPIGMVEDLLVNEINVAAVACARKAADQPRFV
AGSIGPTTMQLATFRATTFDKLADSYYAQVKSLCEAGVDILLPETAIDTLNLKSCLFAIQRYRRVPVMVSGTFD-GRTFSGQSVEAFVTALSHFPVLSVG
MNCALGPDIMRPHVEEMSKATGLPISCHPNAGLPNE--MG--AFDLDPKPMAEIVGEYADNGINILGGCCGTTPDHIRVMTERVQGCKPKQEDKSGPV-W
TRLSGQLPMVMRPEIPFTMVGERTNVTGSRKFARLIRNEEYDEAVEVAREQVENGATIIDVNFDDALLDGVEAMTRFLRLIAGVAAVPVMIDSSRWEVIE
AGLQNVQGKAIVNSISLKEEEFLRRARLVRQYGAATVVMAFDEEGQAADEDNKVRICKRAYDLLNEVHFPPEDIIFDPNILTVATGMEEAVDFVNAVERI
KKECGAKTSGGVSNISFSFPVREAIHSAFLYRAVKAGLDMGIVNAGQLEVYEEIPVEDVLWNRRDDATDRMLEFAETVKGSG--KKKSGEDLT-WRIEER
MKHALIKGIDKYIVEDTEEARQHYDKCLHIIEGPLMAGMSVVGDLFGQGKMFLPQVVKSARVMKKAVAYLEPFMEQEKEQD-RGKFLIATVKGDVHDIGK
NIVGVVLQCNNYEVIDLGVMVSSEKILEEAVKQDADMIGLSGLITPSLDEMVHVAREMKRIGMKKPLLVGGATTSAKTAVRDGPVLHVLDASRSVGVVEK
LL-
>tr|D2AXV0|D2AXV0_STRRD Methionine synthase OX=479432 OS=NI 9100). GN= PE=3 SV=1
--ALRELLDQ-RIVVLDGAWGTMLQGAELTAG-DPDLLNLTRPDVVLDVHRQYLAAGADITTTNTFTATSIGQADGLLVREMNLRGAQLARQAADEGRFV
AGSIGPLNVTLSPYRAVSFDEVRAAYAEQIQALADGGVDLLLIETIFDTLNAKAAIAAARDVPHLPLWISVTIVSGRTLSGQTVEAFWSSIEHAAPLVVG
VNCSLGAEEMRPHVAELSRLAGVYTASHPNAGLPNA--FG--GYDQTPDETARLLGEFAGSGVNVVGGCCGTTPAHIARIAAEVSALPPRPIPAP-PA-R
TRFSGLEPFEIGADTGFVMIGERTNVTGSARFRRLVEGGDHQGAVDVALEQVRGGANLLDVNMDADLLDSEQAMTTFLNLIATVARIPVMIDSSRWSVLE
AGLKCVQGRGVVNSISLKEEPFLEQARRIRDYGAGVVVMAFDEQGQADTVERKVAICARAYDLLQRAGFPAEDIVFDPNVLAVATGIAEAKAFIDALPLI
KQRCGARTSGGISNLSFSFVVREAMHSAFLFHAVRAGLDMGIVNAGQLAVYQDIPVEDVIFDRRADATDRLVAFAETVSGS---TRRTVDLS--WRVEQR
LAYALVQGIVDFIDADTEEARQRAARPLDVIEGPLMDGMKIVGDLFGAGKMFLPQVVKSARVMKRSVAYLEPYMEAEKEGRGQGKVVLATVKGDVHDIGK
NIVGVVLGCNNYQVIDLGVMVPAAVVLDTAIAEGADAVGLSGLITPSLDEMVTVAAEMQRRGLKLPLLIGGATTSRQTAVRDGTTVHVLDASRVVGVVSD
LL-
>tr|C1A5U1|C1A5U1_GEMAT 5-methyltetrahydrofolate--homocysteine methyltransferase OX=379066 OS=100505). GN= PE=3 SV=1
--QLDEALAR-RLLIIDGAMGTMLQRHRLTEG-NNDLLVLTQPDIVADVHRQYLAAGADILETNTFNATAISMADGMLAYELNVAGTALARRVADEPRWV
AGVLGPTNRTASPSRNVSYDDLAAAYGEAVRGLVDGGADILLVETIFDSLNAKAALFAIERYTRFPVMISGTITSGRTLSGQTAEAFWNSMAHVQPVSIG
LNCALGAEQLRQYVQELGRVADCHVSAHPNAGLPNA--FG--GYDETPERMAEQIGEWARSGVNIVGGCCGTTPEHIAAIAAAVHQVPPRKRPVL-DH-Q
LHLSGLEPFTVGPTTNFVNVGERTNVTGSARFAKLILEGSYAEALVVARQQVLSGAQVIDVNMDEGLLDAERAMTTFLNLVASIARVPVMVDSSKWTVLE
AGLKCLQGKGIVNSISLKEAEFLRQARLVRRYGAAVIVMAFDEDGQADTVARRVAICTRAYRLLETIGFPPEDIIFDPNIFAIGTGIEEAVDFFAATREI
KRTLHVKVSGGVSNVSFSFPLREAIHAVFLYHAIRAGMDMGIVNAGQLVPYEDIPVEDLVLNRRPDATERLMDVAEQVKGR---AVEDEV----WRVEDR
LSHALVHGIDSHVVADAEEARQLV-HPIEVIEGPLMRGMNIVGDLFGAGKLFLPQVVKSARVMKKAVAHLIPFIEALKTTKSAGRVLMATVKGDVHDIGK
NIVGVVLQCNGYEVIDIGVMQSCAKILDKAREIEADVIGLSGLITPSLEEMSFVASEMERQGFTIPLLIGGATTSKATALKSGPVVHVLDASRAVGVTSS
LL-
>tr|I0XQ28|I0XQ28_9LEPT Methionine synthase OX=1049972 OS=Leptospira licerasiae serovar Varillal str. VAR 010. GN= PE=3 SV=1
--ELLKLLEE-RILVLDGAMGTMIQRYGLGEG-NNDLLVITKPEVIEEIHYKFLEAGANILETNTFSSNRISQADNAYVDELNRKAVKVARAAMEKPLFL
AGSIGPTTRTASPFRAVTFDELVETFYEQVRALVEEGVDILLSETNIDTLNLKAIIVAIENVVRIPVSLSVTITSGRTLSGQTIEAFYNSIYHANPLSVG
INCALGAGEMRPYIEELSRISGCYISCYPNAGLPNA--FG--GYDQTPEEFGSFLDDFSNQGLNIAGGCCGTTPAHIKEGAKAVQGKKPRVIPEI-EG-K
TRLSGLEPLNIDEATGFVLIGERTNVTGSPKFKKLILEGNFEEAVSVALQQVEAGANIIDINFDEALLDGEASMREFLNLIAVIAKVPFMVDSSKWSVLE
TGLKCIQGKPIVNSISLKEEKFLQQAKTIKMYGASVIVMAFDEQGQAATKDDKVRICKRAYDLLEKANFSPFDIIFDPNILTVGTGIEEAVDFIEAIKEI
KAVCGAKISGGLSNISFSFPVREAMHSAFLFHAIKAGMDMAIVNAGMLAVYEEIPVEDVLLNRRSDATERLIEFAESFKS-GE-KAEKKEEA--WRVEQR
LEYSLVKGIVEYIDQDTEEARLKYDQPLQVIEGPLMDGMRVVGDLFGSGKMFLPQVVKSARVMKKSVAYLLPFMEEENRISKKQKFLIATVKGDVHDIGK
NIVAVVLACNNYEVIDLGVMVPCEKILEEARKENVDIIGLSGLITPSLDEMVHVASEMKRTGFDIPLLIGGATTSSATSVKDQPVVHVLDASRVVNVVGK
LL-
>tr|A1SJZ9|A1SJZ9_NOCSJ Methionine synthase (B12-dependent) OX=196162 OS=Nocardioides sp. (strain BAA-499 / JS614). GN= PE=3 SV=1
--QLTRALEQ-RILVLDGAMGTAIQRDRPDEG-NNDLLTITRPEIIAGIHREYLLAGADIIETNTFNANAVSLSDGMLAYEINYEAAQLARREVDAPRYV
AGALGPTTRTASPARNVTYDQLVAAYLDAARGLVDGGADLLVIETIFDTLNAKAAIFAVETLRRWPVIISGTITSGRTLSGQVTEAFWNSVRHARPLAVG
LNCALGAKEMRPYIAEIARIADTFVSCYPNAGLPNA--FG--EYDEAAEETAAIIEEFAASGVNLVGGCCGTTPAHVAAIAKAVEGKTRRPVPEL-TP-A
LRLAGLEPFAVTDKSLFVNVGERTNITGSARFRKLIKDGDYDTALSVAAQQVENGAQVIDINMDEGMIDGVAAMDRFTRLIASISRVPVMVDSSKWEVIQ
AGLKNIQGKPIVNSISMKEDTFREQARLCRQYGAAAVVMAFDEDGQADNLERRKAICERAYRILDEVGFPPEDIIFDPNVFAVATGIEEGLDFIEATRWI
KQNLGAKVSGGISNVSFSFPVREAIHAVFLYHAIGAGLDMGIVNAGALVVYDQVEIEDVILNRRPDAAERLLEIAEAHNRATTEAAAAEE----WRVEER
ITHALVKGIDAHVEPDTEELRQLIGRPIEVIEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKKAVAYLIPFIEQEKLKETNGTIVMATVKGDVHDIGK
NIVGVVLQCNNYEVIDLGVMVPTQKLLDTALEVGADAVGVSGLITPSLDEMVGVAAEMQRRGMEIPLLVGGATTSRATAVKDGPVVWVKDASRSVPTLAT
LL-
>tr|F5YN83|F5YN83_TREPZ Methionine synthase OX=545694 OS=Treponema primitia (strain ATCC BAA-887 / DSM 12427 / ZAS-2). GN= PE=3 SV=1
--Q----LTR-RILVLDGAMGTMIQRYKLTEG-CNDVLCLTKPDIISSIHEAYLKAGADIIETCSFNATAVSLADGLLAWEISRASAEIARKQADKPRFV
AGILGGAAKSASPKRSVTWDELEAAYYDNARGLLDGGVDILMVETIYDTLNAKAAIFAISRLIDVPLMISATVASGRILAGQTLEAFCVSVLHAKPWSMG
LNCSFGAGSLKKHVQELAALVPCFVSAHPNAGLPNR--FG--EYDETPETMAAVVEEYLKEGVNIIGGCCGSTPDHIAAIAAKAKNYGPRPLPVP-RKGT
V-FAGLEPLRVSRDGGLTKIGERTNVAGCRKFLKLIKDENYGEALGLVREMIEQGASLINVGMDDPFLDAKACMTRFLNLALAIARLPIVVDSSRWEVIE
TGLKLLQGKGLVNSLSLKDGELLRKARLARRYGAAVVVMLFDEQGQAAGYERKIEIAKRSYDLLG-DGFPPEDIVFDPNILSVATGIPEALDFIHACEWI
TANCGAQISGGVTNLSFSFTVREAMHAVFLKHGIKAGLSMAIVNPGALVPYENLEVESLLLCKSPDAVDRLLSIAVALKDA-A-GTAAKS-AS-WRVEER
VVHAMVKGIDDYIEGDVLELRPRYARPLELVEGPLMRGMGEVSRLFGEGKMFLPQVIRSARVMKKAVAVLEPFMERERLNTD-TKILLATVKGDVHDIGK
NIVGVVLGCNGYTVLDLGIMVPAEDILAAAEKEGAKIIGLSGLITPSLEEMVRTAREMEKRGMKIPLIIGGATTSLATALRSGPVVYVSDAGQSAGTVRA
LL-
>tr|K1HLR3|K1HLR3_9FLAO Methionine synthase OX=883153 OS=Myroides odoratimimus CCUG 3837. GN= PE=3 SV=1
----RSLLKQ-RTLVLDGAMGTMLQAYRFSEG-NNDLLSITQPDAVKEVHRQYLLAGADILSTNTFSGTTIAMADHLIVYELNYQSAKIAREVADEPRYV
AGAIGPTNKTASPYRAITFEELRIAYKQQAEALLDGGCDLLLVETIFDTLNAKAALFAIDEIIDIPIMISGTITSGRTLSGQTVEAFLISIAHIPLLSIG
FNCALGAEQLEPYVKQLSQHAAVNISAHPNAGLPNA--FG--EYDQTPTEMKELIDSFLSQNVQIIGGCCGTTPEHIRLIAQAVAEHSKDRQPKQ-FN-L
KPLSGLEPLYVTAEANFINIGERTNVTGSRKFLRLIKEEKFDEALAVAREQVEGGAQVIDINMDEGLLDGVHCMTNFLNLIASIAKVPIMIDSSKWEIIE
AGLRVVQGKAIVNSISLKEELFIEHAKLIKRYGAASVVMAFDEKGQADSLERRIEICQRSYDILNQVNFAPQDIIFDPNIFPVATGMEEALDFFNATKWI
RENLYANVSGGVSNVSFSFKVREAMHAAFLYHAIQHGMNMGIVNPEMLEVYDEVDVEDVLLNRRDDATERLLDFAESIKNES--AIQSTEIE--WRIQDR
LTHALVKGIETYVIEDTEEARLSVPQPIQVIEQYLMNGMNVVGDLFGAGKMFLPQVVKSARVMKKAVAYLLPFIEESKEGNA-GKILMATVRGDVHDIGK
NIVAVVLACNNYEIIDLGVMVPPEKIIETAIKEQVDIIGLSGLITPSLDEMVHLAKELDKVNSNIPIMIGGATTSRVTAVKKNCVVHVHDASRSVTIANQ
LL-
>tr|I4AL61|I4AL61_FLELS Methionine synthase (B12-dependent) OX=880071 OS=NCIMB 1366 / Sio-4). GN= PE=3 SV=1
----TKHLQE-RILVLDGAMGTMIQRHTLEEG-NNDLLSITQPDIIRDIHKKYFEAGADIVETNTFSATTIAMADGMLAYELNYESAKLAKEAATAPRFV
AGAIGPTNRTASPYRAVTFDDLVMAYYEQVRGLVDGGVDLILIETVFDTLNCKAALFAVEKYRNLPIMVSGTITSGRTLSGQTTEAFYNSIAHANIISVG
LNCALGAALMKPYMRELSRVANCFVSCYPNAGLPNE--FG--QYDETASQMSRLLEDFASEGFNIVGGCCGTTPDHIQAIAEEAAKHEPRKIPER-KT-A
MRLSGLEAITLDKSTNFVNVGERTNVTGSKKFSRLIKEGKFQEALDVAKQQVEGGAQVIDINMDEGMLDSKNAMVHFLNLVGSISKLPIMIDSSKWEIIE
AALKCVQGKGIVNSISLKKEKFMEQAKLVRRYGAAVIIMAFDEDGQADTYERKIEICKRSYDIWDELNFPPEDIIFDPNIFAIATGIDEAVDFINATRWI
KENLYAKISGGVSNVSFSFVVREAIHAVFLYHAVKAGMDMGIVNAGMLEVYDNVDVEDVVLNKNPEGTELLVDMAEKYRGEG--KKRVKDET--WRVEKR
LEYSLVNGITEHIIADTEEARLKVEHPLHVIEGALMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAHLIPFLEIEKRKNG--KILLATVKGDVHDIGK
NIVGVVLACNNYDVVDLGVMVPADKILQEAVNHDVDVIGLSGLITPSLDEMVFVAQQMEKQGLKLPLLIGGATTSRITAVKTGSVVHVVDASKAVPVMSN
LL-
>tr|B5JQJ5|B5JQJ5_9BACT Methionine synthase OX=382464 OS=Verrucomicrobiae bacterium DG1235. GN=VDG1235_2991 PE=3 SV=1
--RLRHLLGE-RILFLDGAMGTMIQRHKLEEG-NNELLSLTRPEIIAEIHKAFLEAGSDIIETNTFSATTIAQADGLKVKELNVASARVAKQAVADECFV
AGAIGPTNRTASPYRAVTFDDLREAYLEQIRALGEAGVDLFLPETTFDTLNLKACIFALEEYERMPVMLSVTITSGRTLSGQTIEAFWNSVSHARPLSVG
INCALGAQDMRPYIESLSKIADCYISCYPNAGLPNP--LSETGYDELPADTARFLEDFAQNSVNLIGGCCGTTPEHIKAIADKAREYPSRPIPVI-EP-A
LRLSGLEPFEVIGEKAFVMVGERTNVTGSPRFRKLIKEEKFDDALAVARQQVENGANIIDINFDEGMLDSEACMTKFLNLVASISRVPIMIDSSKWSVIE
AGLKCAQGKCVVNSISLKEEKFLQSASLVRRYGAAVIVMAFDEVGQAATRQDKVRICKRAYDLLEKLNFPPEDIIFDPNILTVGTGMEEAVDFIEATREI
KERCHARVSGGVSNVSFSFPVREAIHAAFLYHAIHAGLDMGIVNAGMLAVYDEIDVEDVLLNRSEDATELLIELAEEVKSSGK-KVEEKIDE--WRVEER
LSHSLVKGISTFVDEDAEEARLKLARPLDVIEGPLMDGMKIVGKLFGEGKMFLPQVVKSARVMKKAVAHLTPFMEAEKQSSSRGKIVLATVKGDVHDIGK
NIVGVVLSCNNYEIVDLGVMVACDKILNTAREIGADAIGLSGLITPSLDEMIHAAKEMERQGFKVPLLIGGATTSKATAIKSGPVVHVTDASLVVGVCND
LM-
>tr|L0A769|L0A769_9DEIO 5-methyltetrahydrofolate--homocysteine methyltransferase OX=937777 OS=Deinococcus peraridilitoris DSM 19664. GN=Deipe_3604 PE=4 SV=1
--DIRALLRE-RILILDGAMGTMIQARQLSEG-NHDLLNLTRPDVIADIHRAFLEAGADILETNTFSSTSIAQADGMWVRALNVEGARIARELADEPRFV
AGSIGPTNRTATPFRAVDFDELVRAYEEQTEALIEGGADLLLIETVFDTLNCKAALFAAQEVRELPIMLSGTITSGRTLSGQTAEAFAASVSHAPLLSLG
LNCALGADMLRPHLRSIAGSTDAFVSIHPNAGLPNA--FG--EYDETPEQMAQVLGEFARDGLNIVGGCCGTTPEHIRAIAEAVETSQPRAPAPL-PA-L
PLFSGLEPLRITPETNFVNVGERTNITGSPKFSQAILAGDYDAGLRIARQQVLNGAQVVDINVDEGLLDSEAVMVRFLNLLAAIARVPLMLDSSRWDVLE
AGLKRVQGKAIVNSISLKEAEFLRQARRIRRYGAAVVVMAFDERGQADNAPRRIEICSRAYQLLEQANFAPQDIIFDPNVLTVATGIPEALDFIEATRWI
KQNLGALVSGGISNVSFSFHVREAMHSVFLYHAIRAGLDMGIVNAGMLAVYDDLEVEDVILARRPDAADRLLEIAERYKGE---KTRAEAAA--WRVRER
LQHALVQGVADFVEVDAEEAYQLLGSPLEVIEGPLMDGMNIVGDLFGSGKMFLPQVVKSARVMKRAVAHLTPYLEAQKQGSRKGRVLLATVKGDVHDIGK
NIVGVVLGCNGYEVTDLGVMVSAEKILAEARRLEVDVIGLSGLITPSLDEMVHVARELERQELTLPLLIGGATTSRTTAVKRAPVVHVHDASRAVTTVGD
LL-
>tr|A3ZUI9|A3ZUI9_9PLAN 5-methyltetrahydrofolate--homocysteine methyltransferase OX=314230 OS=Blastopirellula marina DSM 3645. GN=DSM3645_22204 PE=3 SV=1
--HVIQELDK-RILILDGAMGTMVQKYKLDEN-FTDILCLTRPEIVEQIHREFLEAGADILETNTFGATPVAMEEDLLATDVNVAAIQLARKVVDEPRFV
AGSIGPTSRTASPFRNVTFQQLVDSYLVQIAAMVEAGADLLFPETTFDTLNLKACLFAIEKYVVLPVMASVTID-GRTLSGQTVEAFWNSVAHFPLLSVG
VNCALGADKMRPYVQELASISPAYISCHPNAGLPNE--FG--EYDETPEQMAATLTTFADSGLNIVGGCCGTSPAHIKAIAEAVEHKAPRIRATP-PD-F
TRLSGQQSLTILPTSNFTMIGERTNVTGSRRFARLVREELYEEAIAVALEQVNNGANVIDINMDDALLDGEAAMARYLNLIAAICKAPIMIDSSKWSVIE
AGLRCVQGKPIVNSISLKEADFLAKARLVRSYGAAVVVMAFDETGQAVEKDPKVQICKRAYDLLNEVGFPPSDIIFDPNILTVATGIEEAINFIEACREI
KQVCGAKISGGVSNVSFSFFIREAIHAVFLFHAIKAGLDMGIVNAGQLAVYDDVAIEDVLFNRRDDSTERLVDYAETVKDAG--GSAVTEDLS-WRVQER
LSHALVKGIDKFVVEDTQEARQHYDRCLRIIEGPLMDGMNIVGDLFGAGKMFLPQVVKSARVMKKAVAYLLPIMEEEKAVA-RGTILMATVKGDVHDIGK
NIVGVVLGCNNYSVIDLGVMVSCDKILAAAKKHGVDAIGLSGLITPSLDEMVHVAKEMEAAGFTIPLLIGGATTSAKTAVKSGTTVHVLDASRSVGVVDR
LL-
>tr|E4RR14|E4RR14_LEAB4 Methionine synthase (B12-dependent) OX=649349 OS=Leadbetterella byssophila (strain DSM 17132 / KACC 11308 / 4M15). GN= PE=3 SV=1
--RLRQALRD-RILVLDGAMGTMIQRYKLSDG-NNDLLSITRPDVILAIHKEYLDAGADIIETNTFSGTWVAQDDHMLVYEINYEGAKIARQAADAPRFV
VGSMGPTTKMASPFRAITFDQLVDAFSTQIRALIEGGVDALLIETVTDTLNCKAALYAAKSIFDRPLMVSGTITSGRTLTGQTSEAFYNSVSHAGLLSIG
LNCALGAKAMKPYLAELSRVANCYVSVYPNAGLPNE--MG--QYDETPAYMAEQVREFLEEGVNILGGCCGTTPEHIRAFAELAKNYKPRVPSEP-EP-L
LRLSGLEPLTLTPELGFVNVGERTNVTGSKKFLRLIKSRKFDEALSVAQDQVEGGANVIDVNMDEGMLDGVEAMTTFLNLMAAISRIPVMIDSSKWEIIE
AGLKCIQGKGIVNSISLKEEEFKRQASTILKYGAAVVVMAFDEQGQADTTERRIEISKRSYDILNQLGFPPQDIIFDLNIFPVATGIEEALSFFEATKWV
RENLLVHVSGGVSNVSFSFRVREAIHSAFLYHGRKAGMDMGIVNPSMLEVYDDIPVEDVLLNRTDDATEVLLELAESLKGEG--KAEDKAQE--WRVNKR
IEHALVKGIVEFIDEDIEEIRHQYPTPLQVIEGPLMDGMNVVGDLFGSGKMFLPQVVKSARVMKKAVAYLLPYLEEEKKQNN-GKVLMATVKGDVHDIGK
NIVGVVLACNNYEIIDLGVMVPAEKILEEAQKHQVDAIGLSGLITPSLDEMVYVAKEMQKRDMTDPLLIGGATTSRATAVKNGPVIHVLDASKSVPVVSN
LL-
>tr|H1YAC1|H1YAC1_9SPHI Methionine synthase OX=714943 OS=Mucilaginibacter paludis DSM 18603. GN=Mucpa_2853 PE=3 SV=1
--DIRQELQK-RILIIDGAMGTMIQRYQLTEG-NNDLLNITRPDIIKTIHAEYLEAGADIIETNTFSTQVISLADHLLAYELSYEGARIAREAADEPRFV
AGAIGPTNRTASPYRAVTFDDLVAAYYTQVRGLVDGGSDVLLIETIFDTLNAKAAIFAIKQYKDYPIMISGTITSGRTLSGQTVEAFWNSIRHANLLSVG
LNCALGAKEMRPHIEELSAKASVYISAYPNAGLPNE--FG--AYDEAPHETAHLVEDFMAAGVNIVGGCCGTTPDHISCIAKKTESFPRRQIPKV-ET-F
MRLSGLEAITLTPESNFANVGERTNITGSPKFSKLILAEDYEGALVVARQQVEGGAQVIDVNMDEGMIDSEAAMTKFMNLIASIAKLPIMVDSSKWSVIE
AGLKCLQGKGIVNSISLKEDKFRDSARKIMQYGAATVVMAFDETGQADSLERRIEICKRSYDILNEVGFPAEDIIFDPNILTVATGLEEAVDFIEATRWI
KQNLHAKVSGGVSNISFSFTVREAMHSAFLYHAIQAGMDMGIVNAGMLEVYEEIPVEDVLLNRRPDATERLVEYADTVKSKG--KEIVKDEE--WRVEKR
LSHALVKGIIEYLDADVEEARQKYPKPLEVIEGPLMDGMNIVGDLFGAGKMFLPQVVKSARVMKKAVAYLLPFIAAEKDSNA-GKILMATVKGDVHDIGK
NIVGVVLACNNFEIIDLGVMVPAHKIIEEAKKQNVDIIGLSGLITPSLDEMVHFAKEMEREGFTIPLIVGGATTSRIAAVKSGPAIHVLDASRSVTVCSN
LM-
>tr|L0DC42|L0DC42_9PLAN 5-methyltetrahydrofolate--homocysteine methyltransferase OX=886293 OS=Singulisphaera acidiphila DSM 18658. GN=Sinac_2642 PE=4 SV=1
---LEQILSE-RIMILDGAMGTMIHAHKPTEN-CTEIMALSQPHMIEEIHTAYLEAGSDIVSTDSFNSNAISMADDLYVFELNEAAAAIARRAADAPRFV
AGSLGPTNKMLNSYRPVTFDQLVDAYTEQVRGLVSGGADILLAETAFDTLNLKACLFAIDKYGRLPVMASTTIF-GVTLTSQKVEAFWASMSTYDLFSVG
INCALGADQMRPYVEALSSLAVPYMSCYPNAGLPNA--LG--EFDDSPDHMARRIREFATDGLNLVGGCCGTRPPHIRAIAEAIQDVRPRTRPVR-PS-W
SILSGTDALTIRPESNFMMVGERTNITGSKKFARLIKGGDYDSALSVARDQVEGGANIVDVNMDEGMIDGEEAMTKFLRLIAAITRVPIMIDSSKWSVIE
AGLKCVQGKSIVNSISLKEEKFLEQAKLVHRYGAAVVVMAFDEEGQAVTADRKVEICTRAYELLKQVGFAPADIIFDTNILTVGTGIEEAVEFIEAVRQL
KQMFESKTSGGVSNVSFSYVVREAMNAAFLYHAIAAGLDMGIVNAGQLEVYEEIPVEDVLLNRRPDAADRLTDFAETVKKRG--KKETKDLA--WRVEER
LKHALITGNADFVEADVEEARQSYTRTLSIIEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKKAVAYLLPFMEAEKKRKARGKLLMATVKGDVHDIGK
NIVGVVLGCNDYEVIDLGVMVPCEKILAAAREHEVDMIGLSGLITPSLDEMVHVAKEMEREGFELPLLIGGATTSIKTAVKHGTVIHVKDASRCVGVVDR
LN-
>tr|E9UYC1|E9UYC1_9ACTO Methionine synthase OX=408672 OS=Nocardioidaceae bacterium Broad-1. GN=NBCG_03784 PE=3 SV=1
--TLTATLKE-RIMVLDGAMGTAIQRDRPDEG-NNDLLNLTQPQIIEGIHREYLEAGADIIETNTFNANAVSLIDDMLAYEINYEAARLARAAADAPRYV
AGALGPTSRTASPARNVTYEQLRDAYAEATRALLEGGSDLIFIETIFDTLNAKAAIFGVQQVRRWPVVISGTITSGRTLSGQVTEAFWDSVRHAEPLLVG
LNCALGAQEMRPYIAELARVADAFVSCYPNAGLPNA--FG--EYDEGPSDTAGHIHEFATAGVNLVGGCCGTTPAHIAEIAKQVEAVAPRDVPEV-EP-A
LRLSGLEPFSVTEESLFVNVGERTNITGSAKFRNLIKAGDYDTALSVAAQQVENGAQVIDVNMDEGMIDGVAAMTRFLTLIASISRVPIMIDSSKWEVIE
AGLKLVQGKPIVNSISLKVESFVEHAELCKRYGAAAVVMAFDEDGQADSYERRIAVCERAYRILDEVGFDPEDIIFDPNVFAVATGIEEGVDFIEAVRWI
KQNLGAKVSGGISNVSFSFPVREAIHAVFLYHAIEAGLDMGIVNAGALVPYSEVDIEDVVLNRRADAAERLLEIASKYNKDPEAEAKAEA----WRVGER
ITHALVKGLDAYVEADTEELRAEIGRPIEVIEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKKAVAYLIPFIEAEKQETKNGTIVMATVKGDVHDIGK
NIVGVVLQCNNYEVIDLGVMVPAQKILDAAKEHDADIIGLSGLITPSLDEMVGFATEMQRVGLDLPLLIGGATTSRATAVKDGPVVWVKDASRSVPTAAA
LL-
>tr|C0BM50|C0BM50_9BACT Methionine synthase OX=487797 OS=Flavobacteria bacterium MS024-3C. GN=Flav3CDRAFT_0725 PE=3 SV=1
----KDLIRE-KVLVLDGAMGTMIQEYKFTEG-NNDLLTLTQPEAIQTIHEKYLAAGADIIETNTFSCTTIAMADYMLVYELNYEATRIALKAAEKPRYV
AGSIGPTNRTASPYRAVSFEDLRIAYRQQVEALLDAGVDILLVETVFDTLNAKAALYAIDEVIATPVMVSGTITSGRTLSGQTAEAFLISIAHSDLLSVG
FNCALGAKALLPHLEVLAKKAPFGVSAHPNAGLPNA--FG--GYDESAAEMAAQIQEYVDLGVNIVGGCCGTRPSHIEAIAAIAAKASPRKIIQK--Q-L
GPLSGLEPLILTPDLNFVNVGERTNVAGSKMFLRLIKEELYDQALAVAREQVENGAQIIDINMDDGLIDGEEAMVNFLNLVVAISRVPIMIDSSKWPIIE
AGLRVVQGKCVVNSISLKEAAFLAQALKIKNYGAAVIIMAFDEVGQADNYHRRIEIAKRSYDLLSQIDFPAQDIIFDLNIFPVATGMDEAIDFIKATKWV
RENLGVSVSGGVSNVSFSFPVREAMHSVFLYHAVKAGMNMGIVNPAMLEVYSDIPVEDVILNRREDATERLLDFAEGFVGAK--KESKVDLS--WRLQNR
ITRALVKGLDAYIIEDVEAARNSVSAPIQVIEGHLMTGMNVVGDLFGSGKMFLPQVVKSARVMKKAVAYLLPYIEEAKAQSA-GKILMATVKGDVHDIGK
NIVSVVLACNNYEIIDLGVMVPPDKIIAAAKEHQVDAIGLSGLITPSLDEMVFLAEAMQREGFTMPLLIGGATTSKATAVKGQTVVHVNDASRAVTVVGD
LL-
>tr|I2EYM6|I2EYM6_EMTOG Methionine synthase OX=929562 OS=Emticicia oligotrophica (strain DSM 17448 / GPTSA100-15). GN= PE=3 SV=1
--NIQEILKE-RILVLDGAMGSMIQTFKLTDG-NNDLLSITKPEVIKNIHRQYLEAGADILETNTFSGTWVAMADHMLVYELNYESAKIAREVADEPRFV
AGSMGPTTRLSSPYRAITFDQLVDAFYEQVRGLAEGGVDCFLVETITDTLNAKAALFAISQYKNIPTMVSGTITSGRTLSGQTTEAFLTSVSHLPLLSIG
LNCALGADLMRPYVQILAQKAPFFTSAHPNAGLPNE--MG--EYDQSPEQMALIIDDFLKNGVNIIGGCCGTTPSHIKAIAEVAAKYKPREIPEE-TP-I
QKLSGLEPLNLTKETNFVNVGERCNVTGSKAFARLIRESKYDEALSVARNQVENGAQILDINLDEGMIDGVEAMTTFLNLIAAICRVPIMIDSSKWEVIE
AGLKCVQGKSIVNSISLKVEKFKEYAQKVKDYGAAAVVMAFDESGQADSYERRIEICKRAYDILNEVNFPPQDIIFDPNILTVATGIEEAVDFINATRWI
KENLYAKVSGGVSNISFSFPVREAMHTVFLYHAIQAGMDMGIVNAGQLGVYSDIPCEDVLLNRRPDATERMVAFAETVKSKG--KEQVVDNA--WRVEKR
LAHALIKGITEFIDEDVEEARQKASRPLEVIEGPLMDGMSIVGDLFGAGKMFLPQVVKSARVMKKAVAYLQPFIEAEKGA---GKILLATVKGDVHDIGK
NIVGVVLGCNNYEIIDLGVMVPTQKILDEARKHNVDIIGLSGLITPSLDEMVGVAKEMERQGFSIPLLIGGATTSRITAVKSGPAIHVLDASRAVPVAGK
LM-
>tr|E3JAH3|E3JAH3_FRASU Methionine synthase OX=298654 OS=Frankia sp. (strain EuI1c). GN= PE=3 SV=1
--ELRDLLAQ-RVVVVDGAYGTMLQSVGLTPG-DPDLLNLTRPDVIRDVHHQYLVAGADVITTNTFTATSIGQGDALLVREMNLAGAALARKVADETRFV
AGSIGPLNVTLSPYRAVTFDEVKASYAEQISALADGGVDLLLIETIFDTLNAKAAIAAAKEAPELPLWISVTIVSGRTLSGQTVEAFWASIAHADPLVVG
LNCSLGAAEMRPYVAELSALAGTHIASYPNAGLPNA--FG--GYDQTPAEAGQLLGEFATSGVNIVGGCCGTTPAHIASVAGAVKGVTPRALPDR-PA-R
TRFSGLEPFEIAPSTGFVMIGERTNVTGSARFRRLIEADDYQAAVDVALEQVRGGANLLDVNMDADLLDGEQAMTTFLNLIATVARIPIMIDSSKWSVLE
AGLRCVQGKGVVNSISLKEEPFLDHARLIRSYGAGVVVMAFDEQGQADTTERKVAICGRAYDLLQKIGFPAEDIIFDPNVLAVATGIAEAKAFIDALPLI
KERCGVHLSGGISNLSFSFVVREAMHSAFLYYAVTAGLDMGIVNAGQLAVYSDIPVEDVLFDRREDATDRLVTYAEELRAS---PRKGADLS--WRVEER
LSHALVRGIVDFIEEDTEEARAKSARPLDVIEGPLMDGMKIVGDLFGAGKMFLPQVVKSARVMKRSVAYLEPYMEAEKAGRGAGKVVLATVKGDVHDIGK
NIVGVVLGCNNYEVIDLGVMVPTAKILDTAVAEGADAVGLSGLITPSLDEMVSVAAEMDRRGLKLPLLIGGATTSRQTAVRQGTTVHVLDASRVVGVVSD
LL-
>tr|D0MF55|D0MF55_RHOM4 Methionine synthase OX=518766 OS=(Rhodothermus obamensis). GN= PE=3 SV=1
--PLARLLQE-RILILDGAMGTLIQRHRLAEG-NNDLLVLTQPELIRDIHRAYLEAGADLIETNTFNANAISQADGLLVYELNVAAARLAREVADEPRFV
AGAIGPTNKTLSPYRAVTFDEMVAVYREQVRGLLDGGVDVLLVETVFDTLNCKAALFAIQEERAVPVMVSGTIVSGRTLSGQTPEAFWISIAHMPLLSVG
LNCALGSGQMRPFIEELARVATVFTSLYPNAGLPDE--LG--QYREMPEYMAAQLADYAREGLNLAGGCCGTTPEHIRAIAEALEGLPPRRIPEV-PR-T
LRLSGLEPLVFRPDLNFVNIGERTNVTGSRRFARLIREGRYEEALDVAREQVENGAQMIDVNMDEGLLDGVQAMTTFLNLIATIARVPVVIDSSKWEVIE
AGLKCLQGKGVVNSLSLKEEVFKERARRVRQYGAAVIVMAFDEQGQADTLERRIEICRRAYRILEEVGFPPEDIIFDPNIYAVATGIPEAIDFLEATRWI
KANLYARVSGGISNLSFSFPVRQAMHTVFLYHAVQAGMDMGIVNPGQLGIYEEIDIEDVLFDRRPDATERLIALAQTLTQS---ADAAESLA--WRVEER
LRHALVKGITEFIEEDVEEARQKYGSPLAVIEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKKAVAYLVPFLEAEKQTRPRARILLATVKGDVHDIGK
NIVGVVLQCNGFEVIDLGVMVPADRILEEARRHRVDLIGLSGLITPSLDEMVHVARELERAGFDTPLLIGGATTSKVTALKHAPVVHVLDASRAVPVASA
LV-
>tr|D7CTS8|D7CTS8_TRURR Methionine synthase OX=649638 OS=RQ-24). GN= PE=3 SV=1
--ALQEALKR-RVLVLDGAMGTMIQRHNLTEG-ANDLLTLTQPELIEGIHRAYLEAGADIIETNTFSATRVGMSEGVVLYELNVQAARLARRAADAPRFV
AGALGPTNRTASPFRAVDFDTLVASYYEQVRGLLEGGADIILIETVFDTLNCKAALFAAESVVQLPLMVSGTITSGRTLSGQTLEAFLISVSHAPLLSVG
LNCALGPKELGPYVAELSRLTGLYTSVYPNAGLPNA--FG--GYDETPASMQRTMAAWLNEGVNLIGGCCGTTPEHIAAFAEAAAGVPPRVPPEL-PP-L
SAFAGLEPLVLRSDSNFVNVGERTNVTGSKKFLRLIREERFDEALSVAREQVEGGAQIIDVNMDEAMLDAERAMVRFLNLVAAIARVPVMLDASKFEVLE
SGLKRLQGKGIVNSLSLKEAVFREQAARVRRYGAAVVVMAFDERGQADTFERRIEICARAYRILHEVGFPPQDIIFDPNIFPVATGIEGALDFFRATRWI
KEHLGALVSGGVSNVSFSFRVREAMHAAFLYHARQAGMDMGIVNPAMLEVYEQIPVEDVLLDRRPDATERLLAFAASVKGG---QKGAKDEA--WRVEKR
LEHALVKGVTDFIEADTEEARQRLGSPLAVIEGPLMAGMNVVGDLFGSGKMFLPQVVKSARVMKRAVAYLTPYLEAEKARTSAGKVLLATVKGDVHDIGK
NIVGVVLACNGFEVLDLGVMVPTEKILETAERENVDVIGLSGLITPSLDEMVEVARALERRGSRTPLLIGGATTSRVTAVKSGLTVHVLDASRSVGVAAR
AA-
>tr|G2LJW7|G2LJW7_CHLTF Methionine synthase (B12-dependent) OX=981222 OS=Chloracidobacterium thermophilum (strain B). GN= PE=3 SV=1
--TLEQALRE-RILVLDGAMGTMIQSHKLQEG-NNDLLCLTRPDIVEAIHRAYLEAGADIIETNSFNAQRISQADGLLSYEMNLAAAQCARRAVEAPRFV
AGALGPTNKTASPARGTTFDELVAAYAEQAEGLLDGGVDLLLPETTFDTLNLKAALFAIEEVQRVPVMASVTVASGRTLSGQTVEAFLISVEHAPLLALG
MNCGFGAAEMRPHVEELAEKSPFYLICYPNAGLPNV--FG--GFDQTPDIMGELLRDFARHGLNIVGGCCGTTPKHIAAIAAAVAGMPPRIPPKP-SR-Y
TRLSGLEALVIRPETNFVNIGERTNVTGSAKFAELIRAERYEDALTIARQQVANGAQMIDVNMDEAMLDSVRAMTCFLNLVVAIARVPIVIDSSKFHVIE
AGLKCVQGKCVVNSISLKEAVFIEQARRIRRYGAAVVVMAFDEIGQADTAARKIEICTRAYRILEQVGFPPEDIIFDPNILAIATGIEEAVDFIEATRVI
KQTLGCKVSGGVSNLSFSFVVREAMHSVFLYHAIRAGMDMGIVNAGQLAVYDEIPVEDVVLNRHPDATERLIAFAESVKGAG--KAAVKDEA--WRVEER
LKHALIKGNADYIETDVEEALQKYGAPLAVIEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKKAVAVLLPYLEAEKAGQANGKVLLATVKGDVHDIGK
NIVGVVLGCNNYEVIDLGVMQPCDVILAKAREHNVDVIGLSGLITPSLDEMVHVAKTMTEAGFTVPLLIGGATTSKLTAVKSGTTVHVLDASRAVGVVGA
LT-
>tr|D2QXK9|D2QXK9_PIRSD Methionine synthase OX=530564 OS=staleyi). GN= PE=3 SV=1
--DLESLLED-RVLVLDGAMGTMIQRLDLDER-FSDILCLTRANDITEIHRKYLAAGADIIETNTFGASVIGMEEDLLVREINFAAVKCARIACDEPRFV
AGSIGPTTKQTATYRAVTFEQMVESYSGQIEALVEAGVDIILPETVIDTLNLKACLFALERHERTAVMVSGTFN-GVTFSSQNVEAFWNSIAHVPLLSVG
MNCALGPDVMRPHLEELQRVSGAKISCYPNAGLPNE--MG--QYDLGPAGMANIIGEFLDERLNIVGGCCGTTPDHIAAIAERTRRAKPHKIAEK-PA-W
LRLSGTEAFTLRPESNFVMVGERTNVTGSKAFARLIRDEKYEEAVDVARQQVAGGATIIDVNMDDALLDGEAAMTRFLRLIAGASKVPVMIDSSKWSVLE
AGLRCVQGKAIVNSISLKEEEFLRRAELVRRYGASAVVMAFDEGGQAVEIDHKVSICKRAYDLLQKIGFPPEDIIFDPNILTVATGIEEAVNFIEATRII
KQVCGAKVSGGVSNISFSFVVREAMHSAFLYHAIRAGLDMGIVNAGQLAVYEEIPVEDVLLNRSDDATEKLVALAETVKGKG--KVAAGEDLT-WRVEGR
LRHALVKGIDRFVETDVEEARQKYPKCLSIIEGPLMDGMTVVGDLFGEGKMFLPQVVKSARVMKKAVNYLLPFMEQEKLES-RARVLMATVKGDVHDIGK
NIVGVVLACNNYEVIDLGVMVPCEKILQTAVEKKCDIIGLSGLITPSLDEMVHVAKEMSRQNIKIPLLIGGATTSAKTAVKAEPVVHVLDASRCVGVVDK
LL-
>tr|A6BZ53|A6BZ53_9PLAN Peptidase S26A, signal peptidase I OX=344747 OS=Planctomyces maris DSM 8797. GN=PM8797T_28509 PE=3 SV=1
--ALYSAVQK-RILILDGAMGTMIQNHKLKEG-NNDLLSLTQPEIIRGIHREYLEAGADIIETNTFNGTRLSQSDQMLVHELNLESARLAREVADEPRWV
AGILGPTSRTCSPARNVTYDELVENYLESIDGLVKGGADLILIETIFDTLNAKAAVFAVKTYLELPIMISGTITSGRTLSGQTTEAFWNSLSHAKPFSIG
LNCALGAQELRQYVKELSRVADTYVSAHPNAGLPNE--FG--EYDQSAAEMAEIVDEFASSGLNILGGCCGTTPAHIKAIAEAMEKHYPRPIPEI-EP-A
LRLSGLEPFNVTKDSLFVNVGERCNVTGSARFKRLIKEDDYDTALEVALEQVQNGAHVMDVNMDEGMLDAVKAMTLFLNLVATIARVPVMVDSSKWEVIV
AGLKCIQGKPIVNSISLKEAEFLERARLCQMYGAAVVIMAFDEEGQADTQQRKTEICARSYKLLEQLDFPPQDIIFDPNIFAVATGIDEAVDFIEATRWI
RQNLYASVSGGVSNVSFSFPVREAIHSVFLYYAIQAGMNMGIVNATQLAVYDDLPVEDVILNRTPEGTEALLAIAEEYRGD-S-KMEDLS----WRVTKR
IEHALVKGISTYIIEDAELARQEL-RPLDVIEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKQAVAYLQPYIEMEKQSKPNGRILMATVKGDVHDIGK
NIVGVVLQCNNFEVIDLGVMVPCETILKTAREKQCDVIGLSGLITPSLDEMVTVAAEMERLGMDLPLMIGGATTSKATAVKRNQVVYVPDASRAVGVAAA
LI-
>tr|B3QTZ4|B3QTZ4_CHLT3 Methionine synthase OX=517418 OS=Chloroherpeton thalassium (strain ATCC 35110 / GB-78). GN= PE=3 SV=1
--DIIKLLQE-RILVLDGAMGTLIQRHKLTEG-NNDILVITQPEIIKDIHRQFLEAGSDIIETNTFSSTPISLADEVLTYELNLTATKLAREVADEPRFV
AGSIGPTNKTLSPYRAITFQNVVDAYTEQLKGLLDGGVDILLVETVFDTLNCKAALFAIHEFRRVPVMVSGTVVSGRTLSGQTTEAFWISISHMDLMSVG
LNCALGAKQMRPFVEAMSNVAQTYTSVYPNAGLPNE--FG--EYDDSPEYMAAQIEDFAKSGVNIVGGCCGTTPAHIKAIAETVKTLPPRKRPEP-HH-I
LQLSGLEPLAVDKTTGFINIGERTNVTGSRKFARLIKEGNYDAALSIARQQVESGAQVIDVNVDEGMLDSEKVMAEFLNLIASIARVPIMIDSSKWSVIE
AGLRCTQGKCIVNSISLKEAIFKERAEKILEYGAAAVVMAFDEKGQADSYERRVEICSRAYKILEEVGFPPEDIIFDPNVLTVATGIEEAVDFINSVRWI
KQNLHAKISGGISNISFSFPVREAMHAAFLYHAIREGLDMGIVNAGQLAIYEDIDVEDVLLNRREDATERLVDFAETIKSDG--SKSEAKKE--WRVEER
LKHALIKGIVEHIDEDTEEARQKYPRPLHVIEGPLMDGMNTIGDLFAEGKMFLPQVVKSARVMKKSVAYLIPFIEEEKQKPA-AKVLLATVKGDVHDIGK
NIVGVVLACNNFQVVDIGVMMPCEKIMEAIEKEKPDVVGLSGLITPSLDEMAHVAKEMQRAGMNIPLLIGGATTSKVTAVKSAPVLHVLDASRSVPVVNN
LV-
>tr|H2CLR7|H2CLR7_9LEPT Methionine synthase (B12-dependent) OX=929563 OS=Leptonema illini DSM 21528. GN=Lepil_4200 PE=3 SV=1
----YKELQK-RILVLDGAMGTMIQRHTLTEG-NNDLLSITQPDIIRGIHEAYYAAGSDIVETNTFSSTTIAQADGLLAYELNVASARLAREAADKPRFV
AGAIGPTNRTLSPYRAVSFDEVVDAYYEQITGLVDGGADILLVETIFDTLNCKAALFAIQKYTGRPVMISGTVVSGRTLSGQTVSAFWISVSHVPLLSVG
LNCALGSEQMRPFVSEMARIATCAISLYPNAGLPNA--FG--GYDETPRMMAEVIRDYAAHGLNIVGGCCGTTPDHIRSMAELVSDITPRKPAVD-DH-L
LKLSGLEPLVVTAETNFLNVGERTNVTGSKKFARLILEGNYDEALSVAAEQVESGAQVIDVNMDEGMLDSKAAMDRFLKLIAAISKVPIMIDSSKFDVIE
TGLKCVQGKCIVNSISMKVDAFLEQARRVRAYGAAAVVMAFDEKGQADTYERRINICKQAYDLLNEVGFPPEDVIFDPNIFAIATGIEEALDFIQATEWI
KKNLHAKVSGGVSNISFSFPVRRAMHSVFLYHAIKAGMDMGIVNAGQLDVYDEIECEDVILNRRPDATERLITKAESLKGQG--GEAKEEQA--WRVEER
LKHALVRGIVDFIDEDTEEARQKYGSPLTVIEGPLMDGMNVVGDLFGSGKMFLPQVVKSARVMKKSVAYLIPYLEEEKQRNA--KILLATVKGDVHDIGK
NIVGVVLACNNYDVVDLGVMVPREKILDEAVRENADVIGLSGLITPSLEEMAEVAREMERRGMKVPLLIGGATTSEMTAVKSGPVVHVLDASRSVPVAGQ
LI-
>tr|F0RPU7|F0RPU7_DEIPM Methionine synthase OX=693977 OS=NBRC 101906 / NCIMB 13154 / VKM Ac-1939 / CCM 2703). GN= PE=3 SV=1
--PLHRALQE-RILILDGAMGTMIQRHRLTEG-ANDLLTLTQPQLIEEIHAAYFGAGADIAETNTFSSSRLGLAEGVLIYELNVQGARLARRAAERPRWV
AGAIGPTNRTASPFRAVTFDELVSSYSEQIHGLLDGGVDALLIETVFDTLNAKAALYAAEEVRQVPIMVSGTITSGRTLSGQTLGAFLASISHLPLLSVG
LNCALGPAELRGHVQELSASTPFFTSAYPNAGLPNA--LG--GYDETPQTMLDVMDEWLEQGVNIVGGCCGTTPEHIRAFAAAAQRRSPRVPPHP-SG-L
PTYAGLEVLTLRPESNFLNVGERTNVTGSRRFLRLIRDRQFDEALDVAREQVEGGAQMIDINMDEAMLDSQEAMVEFLNLIASIARVPIMLDSSRFSVIE
AGLKRVQGKAVVNSISLKEAEFLRQAGVLRRYGAAAVVMAFDEQGQADTLERRIAICQRAYTLLAH-GFPPQDIIFDPNIFPVGTGIPEALDFFEAARWI
KANLGALVSGGVSNVSFSFAVREAMNAAFLYHARQAGMDMGIVNPSTLEVYSEIEVEDVLLARRPDATERLLEYSEHVAGG---AKKERDLS--WRVAKR
LEHALVRGITEFIVEDAEAARLELGGALKVIEGPLMDGMNVVGDLFGSGKMFLPQVVKSARVMKQAVAHLEPYLQ-EGQRQSAGRVVLATVKGDVHDIGK
NIVGVVLACNGFEVHDLGVMVPAERILDEAERLQADIIGLSGLITPSLDEMVGVAEEMQRRGGGLPLLIGGATTSRVTAVKGGLTVHVLDASRSVGVTAR
AI-
>tr|K5ZDU9|K5ZDU9_9PORP Methionine synthase OX=999418 OS=Parabacteroides goldsteinii CL02T12C30. GN=HMPREF1076_04190 PE=4 SV=1
--EFIRSLQE-RILILDGGMGTMIQGFKLNEG-NNDLLCITRPDVIKSIHRQYLDAGADIFATNTFNANAISMEDAMYVREINLAAGKLGREVADETIFV
AGSIGPTNKTASPYRAVTYKDVYKAYKEQVEALIDSGVDLILFETTFDTLNVKAGLEAAETAKDLPIMLSLTLSGGRTLSGQTLGAFLASVQHINLVSIG
LNCSFGATDMKPYLAELAKHAPYFISAYPNAGLPNS--FG--TYDETPEKMAVHVKPFIEEGVNIIGGCCGTTPAHIAQYPALVKGAKS-HVPAP-EPDC
L-LSGLELLEVKKENNFINIGERCNVAGSRKFLRLIKEGNYEEALTIARKQVEDGAQVIDINMDDGMLDAVKEMTTFLNLVASIARVPVMIDSSKWEVIE
EGLMCVQGKSIVNSISLKEEVFLAHAARIKQLGAAAVVMAFDEKGQADTFERKAEVCGRAYRLLEKIDFDPNGIIFDPNVLAIATGMEEGLDFIRAVEWI
KQNLGAKVSGGISNLSFSFYVREAMHSVFLYHAIGKGLDMGIVNPSSAVLYEDIELEDVILYRRPEAAEELIAYAQNLVEKGG-TEEKHE-A--WRLKER
LEYALIKGIGDHLEEDLQEALKAYPRAVDIIDGPLMSGMNKVGELFGAGKMFLPQVVKTARTMKKAVAILQPAIEAQKSAKA-GKVVFATVKGDVHDIGK
NIVSIVLACNNYEVIDLGVMVPAEVIVQTAMKEQPDLVCLSGLITPSLEEMVHVTDEMQKAGLTIPIMVGGATTSKLTAIKDYPVIHVLDASQNPLIAAK
LL-
>tr|H8KWP1|H8KWP1_SOLCM 5-methyltetrahydrofolate--homocysteine methyltransferase OX=929556 OS=NCIMB 12057 / USAM 9D) (Flexibacter canadensis). GN= PE=3 SV=1
--DIRNILTK-RILVLDGAMGTMIQRYKLQEG-NNDLLSITRPDVIKAIHREYLEAGADIIETNTFSGTTIAMADQMLAYELNYESAKIAKEVTAEPRFV
AGAIGPTNRTASPFRAITFDQLVEAYTEQVHGLVSGGADIILVETIFDTLNAKAALFAIDQYIKLPIMVSGTITSGRTLSGQTAEAFLISLSNFDLLSIG
FNCALGAKDMRPYLEEISEKAPFFVGAYPNAGLPNQ--FG--EYDETPDQMLDQIRDFLKSGINIVGGCCGTTPDHIRAIADEVAKYAPRKKAEP-QP-F
LRLSGLEPIVITPETNFVNVGERTNITGSPKFSKLILSGDYEGALAVARQQVEGGAQVIDVNMDEGMLDSEAAMVKFLNLIASIAKLPIMIDSSKWSVIE
AGLKCLQGKGIVNSISLKEEKFKEHARKIKRYGAATVVMAFDEKGQADTYERRIEICERSYKLLNEIGFAPQDIIFDPNILTVATGLDEAVDFIETARWI
KQNLLAKVSGGVSNISFSFTVREAMHSAFLYHAIKAGLDMGIVNAGMLEVYEEIPVEDVLLNRKPDATEHLVAFAETVKAKG--KTIVKDEE--WRVEKR
LSHSLVKGIIEYLEEDVEEARQKYDRPLQVIEGPLMDGMNVVGDLFGSGKMFLPQVVKSARVMKKAVAYLLPFIEAEKEEGA-GKILLATVKGDVHDIGK
NIVGVVLACNNYQIIDLGVMVSCQQILETARKENVDIIGLSGLITPSLDEMVHVAKEMEREGFNIPLLIGGATTSRVTAVKNGPVVHVLDASRSVPVAGN
LL-
>tr|K5ZNJ2|K5ZNJ2_9PORP Methionine synthase OX=999421 OS=Parabacteroides merdae CL09T00C40. GN=HMPREF1078_03051 PE=4 SV=1
--EFLNLLKE-RILILDGGMGTMVQGFKLTEG-NNDLLCITRPDVIKSIHRQYLDAGADIFATNTFNANAISMEDGMQVRNINLAAGKLAREVADGTIFV
AGSVGPTNKTASPYRAVTYLDLYSAYKEQVDALVDGGVDIVLFETTFDTLNVKAGLEAAEAVKDLPIMLSLTLSGGRTFSGQTLLAFLASVQHTNIVSVG
LNCSFGAADMKPFLAELAKHAPYYISAYPNAGLPNS--FG--SYDETPEKMAVHVKSFIDEGVNILGGCCGTTPAHIAKYPELVKGAKP-HVPAP-RPDC
L-LSGLELLEVKPENNFVNVGERCNVAGSRKFLRLIKEENYEEALTIARKQVEDGAQVIDINMDDGMLDAVKEMTTFLNLIASISRVPVMIDSSKWEVIE
KGLMCVQGKSIVNSISLKEEVFLQHAARIKQLGAATVVMAFDEKGQADTFERKIEVCGRAYRLLEKVDFDPNGIIFDPNVLAIATGMEEGLDFIRAVEWI
KKNLGAKVSGGVSNLSFSFYVREAMHSVFLYHAINKGMDMGIVNPSSSVLYEDIELEDVILACRPEAAEELIAYAQNLHKAEG-EGEKQE-V--WRLKER
LENALIKGVGDHLEEDLKEALKEYPRAVDIIDGPLMGGMNKVGELFGAGKMFLPQVVKTARTMKKAVAILQPAIEAEKVAKA-GKVLFATVKGDVHDIGK
NIVSIVLACNNYEVIDLGVMVPADVIVKKAIEEKPDLVCLSGLITPSLEEMVHVTDEMQKAGLSIPIMVGGATTSKLTAIKDYPVIHVLDASQNPLIAAK
LL-
>tr|F4C4Y7|F4C4Y7_SPHS2 Methionine synthase OX=743722 OS=Sphingobacterium sp. (strain 21). GN= PE=3 SV=1
--SIREELNK-RILIIDGAMGTMIQPYGLSEG-NNDLLNITQPLIIKEIHEAYLEAGADIIETNTFSSQVISMADQMLVYELNYEGARIAKEAATQPRFV
AGAIGPTNRTASPYRAVTFDDLVNAYYEQVRGLIDGGADVLLIETIFDTLNAKAAIFAIIQYKRSEIMISGTITSGRTLSGQTVEAFLNSINHGNILSIG
LNCALGAKEMRPHIEELSEKAGCYVSAYPNAGLPNE--FG--GYDEQPHETAHLIEDFIESGVNIVGGCCGTTPKHIRCIADKAAKAKPRKVPKP-EP-F
LRLSGLEPITYTPNSVFMNIGERTNVTGSPKFAKLILSGDFEAALSVARQQVEGGAQVIDVNMDEGMLDSEAAMTRFLNLIASIAKLPIMVDSSKWSVIE
AGLKCLQGKGIVNSISLKEDLFKERATTIMHYGAAVVVMAFDEVGQADSYERRIEICKRSYDILNEVGFPPQDIIFDPNILTVATGLEEAVDFINATQWI
KQNLLAKVSGGVSNISFSFVVREAMHAAFLYHAIKAGLDMGIVNAGMLEVYEEIDVEDVLLNRREDATERLVEFAETVKSKD--KAEVKSAE--WRVEER
LSHALVKGIIEFLDDDVEEARLKYPRPLEVIEGPLMDGMNIVGDLFGAGKMFLPQVVKSARVMKKAVAYLLPFIEAEKAKNA-GKILMATVKGDVHDIGK
NIVGVVLACNNFEIIDLGVMVPSQKILDEARKHQVDIIGLSGLITPSLDEMVHVAKEAEREGFKIPIMIGGATTSRIAAVKSGTIVHVLDASRSVTVASN
LL-
>tr|A6L929|A6L929_PARD8 Putative 5-methyltetrahydrofolate--homocysteine methyltransferase OX=435591 OS=11152). GN= PE=3 SV=1
--EFLRLLNE-RILILDGGMGTMIQSFKLNEG-NNDLLCITRPDVIQSIHRQYLDAGADIFATNTFNANAISMADAMYVREINLAAGRLSREVADTTIFV
AGSIGPTNKTASPYRAVTYKDLYNAYKEQVEGLVDGGVDIILFETTFDTLNVKAGLEAAEVVKDLPIMLSLTLSGGRTFSGQTLLAFLASIQHTHIVSVG
LNCSFGAADMKPYLQELAKYAPYYISAYPNAGLPNS--FG--TYDETPDKMAQHVKPFVEEGVNIIGGCCGTTPAHISRYPELVKGAKP-HIPAL-KPDC
L-LSGLELLEVKPENNFVNVGERCNVAGSRKFLRLIKEGSYEEALTIARKQVEDGAQVIDINMDDGMLDAVKEMKTFLNLIASIARVPVMIDSSKWEVIE
EGLMCVQGKSIVNSISLKEEVFLKHAARIKQLGAAAVVMAFDEKGQADTYERKIEICERAYRLLEKIDFNPQDIIFDPNVLAIATGMEEGLAFIRAVEWI
KKNLGAKVSGGVSNLSFSFHVREAMHSVFLYHAIGKGMDMGIVNPSTSVLYEDIELEDVILARRPEAAEELITYAQNLHQAGE-TPEKHE-A--WRLKER
LEHALIKGIGDYLEDDLQEALRTYSHAVDIIDGPLMSGMNKVGELFGAGKMFLPQVVKTARTMKKAVAILQPAIESEKKAKA-GKVIFATVKGDVHDIGK
NIVSIVLSCNNYEVIDLGVMVPADVIIKKAIEEKPDLVCLSGLITPSLEEMAHVADEMQKAGLTIPMMVGGATTSKLTAVKDYPVIHVLDASQNPLIAAK
LL-
>tr|I8QXF0|I8QXF0_9ACTO 5-methyltetrahydrofolate--homocysteine methyltransferase OX=710111 OS=Frankia sp. QA3. GN=FraQA3DRAFT_4715 PE=3 SV=1
--ALRELLAK-RVVVLDGAWGTMLQNAGLTPG-DPDLLNLTRPDIILDVHRQYLAAGADITTTNTFTATSIGQADGLLVREMNLRGARLARQAADEGRFV
AGSIGPLNVTLSPYRAVTFDQVRAAYAEQIEALADGGVDLLLIETIFDTLNAKAAIAAAREVPHLPLWISVTIVSGRTLSGQTVEAFWSSIAHANPLVVG
VNCSLGAEEMRPHVEALARIAGTYTACHPNAGLPNA--FG--GYDQTPAEAGRLIGEFAAAGVNIVGGCCGTTPAHIAQIAAAVQGTAPRQVPTP-TP-R
TRFSGLEPFEIGEDTGFVMIGERTNVTGSARFRRLIEADDYQAAVDVALEQVRGGANLLDVNMDADLLDSEQAMTTFLNLLATAARLPIMIDSSRWSVLE
AGLRCVQGKGVVNSISLKEEVFLDHARRIRDFGAGVVVMAFDEQGQADTTERKVAICGRAYDLLQKIGFPATDIIFDPNVLAVATGIAEAKAFIDALPLI
KQRCGVRISGGISNLSFSFVVREAMHSAFLLHAVRAGLDMGIVNAGQLAVYADIPVEDVLFDRREDATDRLVAFAETVSGK---TQRVVDLS--WRVAQR
LSHALVHGIVDFIEADTEEARAAAARPLDVIEGPLMDGMKIVGDLFGSGKMFLPQVVKSARVMKRSVAYLEPFMEAEKARRGNGKVVLATVKGDVHDIGK
NIVGVVLGCNNYEVIDLGVMVPAKVILDTAVAEGADAIGLSGLITPSLDEMVAVAAEMQRRGLTLPLLIGGATTSRQTAVREATTVHVLDASRVVGVVSD
LL-
>tr|F8WYP8|F8WYP8_9PORP Methionine synthase OX=742767 OS=Dysgonomonas mossii DSM 22836. GN=HMPREF9456_01018 PE=3 SV=1
---IQDILKE-RILILDGAMGSLIQQYKLKEG-NNDLLNLTRPDIIEEIHRKYLDAGADIIETNTFNATAISLEDNMLAKEINREAAKIAKKAAIDPRFV
AGSIGPTNKTASPYRAVTFDDLSSAYKEQIEGLADGGVDLLLIETIFDTLNAKAALFAAEEVIELPIMISVTLSAGRTLSGQTIGGFLASVNHIDYLSVG
LNCSFGASDMKPFLKELARMAPSFISAYPNAGLPNQ--FG--EYDQTPDIMAEQISEFIGEGVNIIGGCCGTTPEHIAKYVDLVKDAKP-HKPAE-KPKY
M-LSGLELLEAKPEINFINIGERLNVAGSRKFLRLIKEEKYEEALTIAHKQVEDGAQVLDVNMDEGLLDGVKEMTTFLNMMASVSRIPVMIDSSKWEVLE
AGLKCVQGKAIVNSISLKEEEFLRHARLVRQYGAAVIIMAFDETGQADTFSRRIEICERAYKLLND-GFDPLDIIFDPNILAIATGIEEAVDFLETITWI
KKNLHAKISGGVSNLSFSFYVREAMHAVFLYYAIQRGMDMGIVNPGQSVVYDDIPVEDVIFNRRPEATDELIEYAERIKEKGQ-TEQKVE-E--WRLDER
IQYSLIKGISDHLEEDLEEALKVYPKAVDIIDKPLMDGMNKVGDLFGSGKMFLPQVVKTARTMKRAVAILQPTLEAQKSNKA-GKLVIATVKGDVHDIGK
NIVAIILACNNYEVIDLGVMTPPEVIIQKVKEEQPDILCLSGLITPSLEEMSIVAHEMEKAGFSIPLMIGGATTSKLTAIKNNSVVYVKDASQAPAAVSK
LI-
>tr|G8UNZ5|G8UNZ5_TANFA Methionine synthase OX=203275 OS=(Bacteroides forsythus). GN= PE=3 SV=1
--KIQQLLDE-RILILDGGMGTMIQGFKLTEG-NNDLLNITRPEVIRSIHRQYLDAGVDIFTTNTFNANAISMDDGMLVREMNLAAGRLTRQLADDSIFV
AGSLGPTNKTASPFRAVSYMDLFRAYHEQVEALIDGGVDLILFETTFDTLNVKAGLEAALDVRERPIMLSLTLSGGRTFSGQTLAAFLASVQHIPLMSIG
LNCSFGAADMKPYLKELGDIAPYFISAYPNAGLPNQ--FG--RYDETPEKMAAQIKDFIDEGVNIVGGCCGTTPEHIAQYSELILHARP-HMPVP-PPDA
L-LSGLELLEVKPENNFLNIGERCNVAGSRKFLRLIKEKNYEEALTIARKQVEDGAQVLDINMDDGLLDAVEEMKTFLNLIASISRVPVMIDSSKWQVIE
EGLMCVQGKSIVNSISLKEEEFLIRAARIRQLGAATVVMAFDEQGQADVFERKIEVCERAYRLLEKIGFPPQDIIFDPNVLAIATGMPEGLDFIRSVEWI
KKHLGAKVSGGVSNLSFSFYVREAMHSVFLYHAIREGMDMGIVNPSASVTYEDIELEDVILARRPEAAEELIAYAQSHIQAGE-QEKTHD-A--WRLDER
LEYALLKGIGDFLETDLKEALQRYGQAVAIIDGPLMNGMNRVGKLFGAGKMFLPQVVKTARTMKKAVAILQPAIEAQKTAKA-GKVVFATVKGDVHDIGK
NIVSIVLTCNNYEVIDLGVMVPAEKIIETVRNEKPDLLCLSGLITPSLEEMVHVTDEMQKAGFSTPIMIGGATTSKLTALKDHPVIHVVDASQNPLIAAK
LL-
>tr|B4S4L0|B4S4L0_PROA2 Methionine synthase OX=290512 OS=Prosthecochloris aestuarii (strain DSM 271 / SK 413). GN= PE=3 SV=1
--TPQSLLEK-KILVLDGAMGTMIQRHKLEEG-NNDILVLTQPEIIYDIHCDFLEAGADIIETNTFNANPVSQADGTLIKELNLSAASIARRAADAPRYV
AGSMGPTNKTLSPYRAVTFQDVVDNYILQLDGLVEGGVDLLLVETVFDTLNCKAALYAIEEHKNLPIMISGTVVSGRTLSGQTTEAFWISVAHTNLLSVG
LNCALGSKQMRPFVEALSGIAESYVSVYPNAGLPNE--FG--EYDDSPEYMASQIADFARSGVNIVGGCCGTTPDHIRAIARDVAAIEPRRKPKA-SH-E
LQLSGLEPLLVNKTTGFINIGERTNVTGSRKFARLIKEENYDEALSVAREQVENGAQVIDINVDEGMLDSEKVMHEFINLIASISKVPLMIDSSKWSVIE
SGLRCSQGKCIVNSISLKEELFKQRAKKILQYGAATVVMAFDEKGQADSLERRIEICSRAYSILEEVGFPPEDIIFDPNVLTVATGIEEAVDFIESVRWI
KQNLFAKISGGISNVSFSFPVREAMHAAFLYHAIHAGLDMGIVNAGQLAIYQDIEVEDVLLNRRKDATERLVDYAGSISEDT--TKNSPKKE--WRVEKR
LEHALIKGIVDFINEDIEEARLKYASPLKVIEGPLMHGMDVIGDLFAAGKMFLPQVVKSARVMKKGVAYLIPFIEEEKKSAA-AKVLLATVKGDVHDIGK
NIVSVVLACNNYDVVDIGVMMPCEKILDAAEKEHADIIGLSGLITPSLDEMVHIAKEMERRGMTIPLLIGGATTSKVTAVKSGPIVHVLDASRSVPAVNN
LV-
>tr|H1XWI1|H1XWI1_9BACT Methionine synthase OX=880073 OS=Caldithrix abyssi DSM 13497. GN=Calab_2209 PE=3 SV=1
--RIRSQLEK-RILVLDGAMGTMIQRYRLGEG-NNDLLSLTQPDIIREIHAAYLDAGADIIETNTFNANAISLADQMLVYEMNRASAQLARQAADAPRFV
AGSVGPTNRTLSPYRAVTFDQVVDAYYQQVKGLIEGGVDLILIETIFDTLNAKAALYAIQNCTHLPIMISVTIVSGRTLSGQTLEAFWVSIKPYPIFSVG
LNCSLGPEEMRPFIEELSKMADVYVTLYPNAGLPNQ--FG--EYEATADQMSVVLKEYAAQGLNIVGGCCGTTPEHIRAFVEIVEHLPPRKIPEP-PI-Y
TQFSGLEALTILPTSNFINIGERCNIAGSRKFARLIREGHFEEAVAIARKQVEDGAQILDVNMDEGLIDSVEAMKRFLNLIAAIARVPVMIDSSRWEVIE
AGLKCLQGKSIINSISLKEETFLEHARMARRLGAAVLVMAFDEKGQADTLERRIEVCTRAYRLLEKIHFPPQDIILDPNIFAVGTGMSEALDYLEAVRYI
KAHLYAKVSGGVSNLSFSFLIREAMHSAFLYHAIQAGMDMGIVNAGQITVYEDIPVEDVLFNRRPDATERLIAFAQQARQS---EEKKLA----WRVEER
LHYALIKGITEFIEADTEEAYQKYGDPIKVIEGPLMEGMKTVGDLFGSGKMFLPQVVKSARVMKKAVAHLTPYLEALKLSTARGKILLATVKGDVHDIGK
NIVGVVLGCNNYEIIDLGVMVPAEKIIEAARALKVDIIGLSGLITPSLDEMVHVAKELDRQGLDLPLLIGGATTSQKTAVKRGLAVYVPDASQSVGVVSN
LL-
>tr|B3EG82|B3EG82_CHLL2 Methionine synthase OX=290315 OS=Chlorobium limicola (strain DSM 245 / NBRC 103803). GN= PE=3 SV=1
--TLLQLLEQ-RILVLDGAMGTMIQRHKLQEG-NNDMLVLTQPDIIYAIHCDFLEAGSDIIETNTFNANPISQGDNALVRELNLEAARLARKAADAPRFV
AGSIGPTNKTLSPYRAVTFREVVDNYIVQLEGLMEGGVDLLLIETVFDTLNCKAALFAVEEYRRVPVMVSGTVVSGRTLSGQTTEAFWISIAHMDLISVG
LNCALGSKQMRPFIEALSGIAESYVSVYPNAGLPNE--FG--EYDDSPAYMAAQIAGFAESGVNIVGGCCGTTPQHIKAIADAVSSLKPRRKPEP-KH-E
LQLSGLEPLMVNQTTGFINVGERTNVTGSRKFARLIKEGNYDEALSIARQQVESGAQVIDVNVDEGMLDSEKVMKEFLNLIASISRVPVMIDSSRWSVIE
EGLQCVQGKSIVNSISLKEDPFRERALKILQYGAAAVVMAFDEQGQADSLERRKEICGRAYDILREVGFPPEDIIFDPNVLTVATGIDEALDFIESVRWI
RENLYAKVSGGISNVSFSFPVREAMHAAFLYHAIRAGLDMGIVNAGQLAIYEDIEVEDVLFNRRPDATERLVSHAETIREGG--EKIEAKAE--WRVEER
LRHALVKGIVEYIDVDTEEARQLYPSPLQVIEGPLMDGMNTIGDLFAEGKMFLPQVVKSARVMKRSVAWLIPYIEEEKQKPA-ARVLLATVKGDVHDIGK
NIVSVVLSCNNYEVIDIGVMMPCDRILDAVEREKADILGLSGLITPSLDEMVHVAREMERLGMKIPLLIGGATTSKMTAVKSGPVVQVLDASRSVPVVSS
LL-
>tr|A4CPQ9|A4CPQ9_ROBBH 5-methyltetrahydrofolate--homocysteine methyltransferase OX=313596 OS=Robiginitalea biformata (strain ATCC BAA-864 / HTCC2501 / KCTC 12146). GN= PE=3 SV=1
----SDLLTE-RILVLDGAMGTMLQRYGFTEG-NNDLLSLTQPKALGEIHRAYLEAGADILETNTFSATSVGMADGMFVYEINRAAAEIAKREAEAPRFV
AGSLGPTNKTASPYRAIDFEALRLAYREQAAGLLDGGVDLFLVETVFDTLNAKAALFAIEELIDTPVMVSGTITSGRTLSGQTAEAFLVSVSHIPMLSIG
LNCALGASQLVPHLEVLSARAGVAVSAHPNAGLPNA--FG--EYDQNPAQMARQVREYLEKGVNIVGGCCGTTPDHIRALAELVAEYKPRQIPDG--R-P
RQLAGLEPLVITPESNFVNVGERTNVAGSRKFLRLVKEGNFEEALEIARDQVDGGAQIIDVNMDDGLIDGKAAMVKYLNLMLAIARVPVMIDSSKWDIIE
AGLQVVQGKSVVNSISLKEAVFLEQARKILLYGAAVIVMAFDETGQADNFERRIEIAERSYRLLEQAGFPPEDIIFDLNIFPVATGMEEALDFIEATRWV
RDNLHCSVSGGVSNVSFSFPVREAMHSAFLYHAIRAGMNMGIVNPTLLEVYDDIPVEDVLLDRREEATERLLEYAETVQGTQ--KDRKTDMS--WRLQDR
ITRALVKGIDQFIEADVEEARQAAGKPIEVIEGHLMTGMNVVGDLFGSGKMFLPQVVKSARVMKKAVAYLTPFIEEAKPQAA-GKVLMATVKGDVHDIGK
NIVSVVLACNNYEIVDLGVMVPPERIIEKAREEDVDIIGLSGLITPSLDEMVFLAREMERQGFRVPLLIGGATTSKATAVKSAAVVHVNDASRAVTVVGD
LL-
>tr|Q0YUB4|Q0YUB4_9CHLB 5-methyltetrahydrofolate--homocysteine methyltransferase OX=377431 OS=Chlorobium ferrooxidans DSM 13031. GN=CferDRAFT_2119 PE=3 SV=1
--TLFTLLEK-RILVLDGAMGTMIQRHKLQEG-NNDILVLTRPDIIYALHCDFLEAGSDIIETNTFNANPISQSDSALVRELNVEAAKLARKAADEPRFV
AGSIGPTNKTLSPYRAVSFEEVVDNYTLQLEGLMEVGVDMLLVETVFDTLNCKAALFSIEEFVRIPVMVSGTVVSGRTLSGQTTEAFWISIAHMDLLSIG
LNCALGSKQMRPFIESISGIAESLVSVYPNAGLPNE--FG--EYDDSPEYMAAQIADFATSGVNIVGGCCGTTPQHIKAIAEAVKGLTPRQRPVK-KH-E
LQLSGLEPLFVNSTTGFINVGERTNVTGSKKFARLIKEGNYDEALSIARQQVESGAQVIDVNVDEGMLESEKVMKEFLNLIASISRVPVMIDSSKWSVIE
NGLQCVQGKSIVNSISLKEELFKERARKVLQYGAATVVMAFDEKGQADSLERRKEICKRAYDILNEVGFPPEDIIFDPNVLTVATGIEEAVDFIESVRWI
KENLFAKVSGGISNVSFSFPVREAMHAAFLYHAIKAGLNMGIVNAGQLAIYEDIEVEDVLLNRREDATERLVSFAETIQGGG--EKIEAKAE--WRVEER
LRHALIKGIVEFIEEDTEEARQLYPSPLQVIEGPLMNGMNAIGDLFAEGKMFLPQVVKSARVMKRSVACLIPYIEEEKKRAA-AKILLATVKGDVHDIGK
NIVAVVLACNNYEVVDIGVMMPCEKILEAVEREKADLLGLSGLITPSLDEMVHVAREMERLGMKIPLLIGGATTSRMTAVKSGAVVQVLDASRSVPVVNS
LL-
>tr|B3QKY2|B3QKY2_CHLP8 Methionine synthase OX=517417 OS=thiosulfatophilum (strain DSM 263 / NCIB 8327)). GN= PE=3 SV=1
--NLYGLIEQ-RILVLDGAMGTMIQRHGLDEG-NNDLLVITQPDIIRSIHCDFLDAGADIVETCTFNANPISQSDQLLTKELNVAAAKVARSAADEPRFV
AGSIGPTNKTLSPFRAVTFQEVVDNYTAQLEGLHEGGVDLLLVETVFDTLNCKAALYAIEQYWQVPVMVSGTVVSGRTLSGQTTEAFWISISHMSLLSVG
LNCALGSKQMRPFIEALSNIAGSYVSVYPNAGLPNE--FG--EYDDSPEYMAAQIAGFAESGVNIVGGCCGTTPTHIRAIAEAVKTLTPRKRPAN-EH-V
LKLSGLEPLVVDETTGFINVGERTNVTGSRKFARLIKEANYDEALSIARQQVENGAQVIDVNLDEGMLDSEKVIVEFLNLIASIAKVPVMIDSSKWAVIE
NGLRCTQGKSIVNSISLKEEPFKEHARKIMQYGAATVVMAFDEQGQADSLHRRIEICSRAYKILEEVGFPPEDIIFDPNVLTVATGIDEALDFIESVRWI
KQNLHAKVSGGISNVSFSFPVREAMHTAFLYHAIHAGLDMGIVNAAQLGIYEDIDVEDVLLNRRDDATERLVAFAETIRDGG--EKAEAKTE--WRVEER
LKHALVKGIVDYIDEDTEEARQLYPSPLEVIEGPLMNGMNHIGDLFAEGKMFLPQVVKSARVMKRSVAVLVPYIEEEKKSAK-AKVLLATVKGDVHDIGK
NIVSVVLACNNFDVVDIGVMMPCDKILDAVVKEKPDVLGLSGLITPSLEEMAHVAKEMERLGMNIPLIIGGATTSKVTAVKSGAVVHVLDASRSVPVVSN
LC-
>tr|B3EN13|B3EN13_CHLPB Methionine synthase OX=331678 OS=Chlorobium phaeobacteroides (strain BS1). GN= PE=3 SV=1
--SLASLLEK-RILVLDGAMGTLIQTYKLEEG-NNDILVLTQPDIIHAIHCEFLEAGSDIIETNTFNANPVSQSDGTLVKHINLEAARLARKAADAPRFV
AGSIGPTNKTLSPYRAVSFKEMADNYREQLEGLIEGGVDLLLVETVFDTLNCKAAILAIEEIVRLPIMISGTIVSGRTLSGQTTEAFWISVAHTGLLSVG
LNCALGAKQMRPFLEALSHVAGSLVSVYPNAGLPNE--FG--EYDDSPEYMASQIADFAQSGVNIVGGCCGTKPEHIRAIAETVATIEPRKKPSM-PT-E
LRLAGLEPLIVNKTTGFINIGERTNVTGSRKFARLIREEKYDEALSIARQQVENGAQVIDINVDEGMLDSEKVMRDFVNMIGSIARVPLMIDSSKWSVIE
SGLCCVQGKSIVNSISLKEDLFRERAKKVMIYGAAAVVMAFDEKGQADSLERRIEICERAYRILDEVGFHPENIIFDPNVLTVATGIEEAVDFIESVRWI
KENLHARVSGGISNVSFSFPVREAMHAAFLFHAIHAGLDMGIVNAGQLAVYDDIEVEDVLLNRRKDATERLVEFAETIKDDG--QKAEAKQE--WRVEER
LQHALVKGIVDYIDSDTEEARQAYASPLDIIEGPLMGGMNVIGDLFAEGKMFLPQVVKSARVMKKAVAWLIPYIEEEKKRPV-AKVLLATVKGDVHDIGK
NIVSVVLACNNFEVVDIGVMMPCENILEAAEKEKADIIGLSGLITPSLDEMVHVAKEMERKGMRIPLLIGGATTSRVTAVKSGPVVQVLDASRSVPAVNS
LL-
>tr|K0X9X8|K0X9X8_9PORP Methionine synthase OX=742726 OS=Barnesiella intestinihominis YIT 11860. GN= PE=3 SV=1
---LKQLLDQ-RILILDGAMGTMIQRYGLNEG-NNDLLCLTAPHLIDEIHRAYLEAGADIIETNSFNANAISMADRLQVKEINRAAARIARKAADDPRFV
AGSIGPTNKSCSPLRNLDFDTLATAYREQITALIEGGVDLLLIETIFDTLNAKAALFAAQESRELPVMLSVTVT-GRTLSGQTLEAFLTAVSHAEILSVG
LNCSFGAREMKPYLHRLASISPYYISAYPNAGLPNR--LG--EYDETPASMAAQIKEFIDEGVNIVGGCCGTTPEHIARYREITQNASP-RRPIA-KDNR
L-ICGLEDLVVCPENNFVNIGERCNVAGSRKFLRLIHEKNYTEALDIARKQVEAGAQIIDINMDDAMLDARKEMVDFLNLIVSIYRVPVMIDSSEWEVIS
AGLKCLQGKAIVNSISLKEETFLAHALEIKRLGAAVVVMAFDEKGQADTYERKIEVCARAYKLLEEAGLAPCDIIFDPNVLAIATGIDSAVDFIRATAWI
HENLGAKVSGGVSNLSFSFFIREAMHAVFLYHAIRNGLDMAIVNPATSITYDDLPIEDVVLNRRPDATERLIDFAEKHREAKK-ENNIDE-D--RHVADR
LKQALVKGISTHLETDLAEAVRQYGSALAVIEQPLMDGMNRVGQLFGDGKMFLPQVVKSARTMKQAVGILQPLIEQENTSKR-GKFIVATVKGDVHDIGK
NIVAVILACNNFEVIDLGVMVPAEKIVERAIAEQVDFIGLSGLITPSLEEMCHVVSEMEKAGLHTPVIIGGATTSKLTAVKSGAVIHAGDASQNPLIAAQ
LL-
>tr|G9S0R1|G9S0R1_9PORP Methionine synthase OX=665949 OS=Tannerella sp. 6_1_58FAA_CT1. GN=HMPREF1033_00347 PE=3 SV=1
---IQDALKQ-RILILDGAMGTMIQRYNLSEG-NNDILCLTQPQIISEIHEAYLQAGSDIIETNTFNATSVSMNDGMHIREINIKAAQLARKAADKPRFV
AGSIGPTNKTTSPFRSLSYDNLVFSYLEQIKALLSGGVDALLVETVFDTLNAKAALFAATAAIHVPIMVSATVSGGRTLSGQTLEAFLASIQHAPILTLG
LNCSFGARDMKPFLKQLSEIAPYYISAYPNAGLPNR--FG--EYDETPEAMANQMREFVEERVNIIGGCCGTTPAHIKLYNELIDGKQP-HIPID-KPNV
L-LSGLERLEIKPENNFINVGERCNVAGSRKFLRLISEKNYEEALGIARKQVEDGAQIIDINMDDAMLDAKSEMITFLNLIASISKVPIMIDSSKWEVIE
SGLKCVQGKSIVNSISLKETIFLEHARMIKKLGAAMVVMAFDENGQADSFDRKIEICERAYKLLQKAGIDPNDIIFDPNVLAVATGIDEGIDFIKATAWI
KKNLGAKVSGGISNLSFSFYIREAMHAAFLFHAVNAGMDMGIVNPGTSVTYTDIPIEDVILNRKPDATEKLIILAEELKRQGK-TVEKKD-I--RDLDER
LEYALIKGISENLETDLSEAMRIYGKAVKVIDGPLMKGMNTVGELFGAGKMFLPQVVKTARTMKQAVAILKPFIEADKAEKA-GKFLLATVKGDVHDIGK
NIVGVVLACNNYEVIDLGVMVPTEKIIKTAIEEKVDIVCLSGLITPSLEEMCHVAEEMEKAGMTIPLMIGGATTSKITAVKSGPVIHVKDASQNPLIAAQ
LA-
>tr|F3ZSM4|F3ZSM4_9BACE Methionine synthase OX=679937 OS=Bacteroides coprosuis DSM 18011. GN=Bcop_0680 PE=3 SV=1
--SFDNLIQE-KILVLDGAMGTMLQSYSFSEG-NNDVLSLTQPQAVQAIHEAYLEVGADIIETNTFSSTTIAQNDNLYVYELNFKSAQLAKKAAEHPRFV
AGTLGPTNKTASPYRAVSFQDLYVAYKQQAEALIDGGCDLLLVETVFDTLNAKAALFAITDIISIPIMLSGTITSGRILSGQTIEAFAISVSHIPLLSIG
LNCAQGAKQLIPYLIQLGKEVRIPLSVHPNAGLPNE--FG--HYDQTPEQMGNDILSFINNPVRIVGGCCGTTPKHIKCIALLVDKQNQ-QTPLF-KQAI
L-LSGLEPFRYTDNITFVNIGERTNVTGSKKFLRLIQNKNYEEALEIAREQVEGGAQILDVNMDEGLLNGTEEMTTFLNLIASIARIPIMIDSSKWEVIE
AGLQCLQGKGVVNSISLKEKKFITYAQKIKQYGAAVVVMAFDENGQADSLERRIEICQRSYNLLHKVHFPAANIIFDPNVFPVATGMEEAIDFFKSTKWI
KNNLFANISGGISNVSFSFTVREAMHSIFLYHGIKHGLTMGILNPTILEIYNEIEIENVFFNRKKNATDTLLQYAESLKGKEN-TATPNL-V--WRLQER
INHALIKGISTFIEQDVEEARQSVEHPIQIIEGHLMIAMNLVGQLFGDGKMFLPQVVKSARVMKQAVTYLLPFIEKLKAASK-PKIVLATVKGDVHDIGK
NIVSVVLACNNYHIIDLGVMVPTENIIQTVLAEQADIIGLSGLITPSLDEMIHVAQELEKAQCTIPLMIGGATTTKLTALKSAPVIHVKDASRSVSVASL
LL-
>tr|D8PED6|D8PED6_9BACT Methionine synthase OX=330214 OS=Candidatus Nitrospira defluvii. GN= PE=3 SV=1
--EVRDLLRE-RILILDGAMGTMIQRYKLDEG-HNDLLNVTRPDVIEAIHRQYLEAGADIIETNTFNSQSVSLADGMLGYELSKAGAECAKRAVAQRCFV
AGAIGPTTKTSSTARGTTYPELVRAYGEQVRGLLDGGVDLLLVETIFDTLNAKAAFFAIQQLRQVPIMASVTIQSNRGFSGQTVEGFWNSISHVPLLSVG
MNCALGPKEMRPLIEELSQIAPIFVSSHPNAGLPNP--LT--GFPETPDSLAPQLREWAQNGLNIVGGCCGTTPDHIRSIATAVNGVTPRQPSKV-EP-Y
LRLSGLEALTVRPESNFVNVGERTNITGSPAFSKLILTGDYDKALTVARQQVEGGAQVIDINMDEGMLDSKAAMQKFLRLLAAIARVPIMVDSSKWEVIE
EGLRNMQGKGIVNSISLKEAKFLEQARLIRRYGAAIVVMAFDERGQADSVARRIEICERSYRLLEQVGVPPQDIIFDPNILTVATGLEEAVDFIEATRWI
KQHLLAKVSGGVSNISFSFVVREAMHAAFLYHAIQAGLDMGIVNAGQLAVYEEIPVEDVLLNRRPDATERLVTFADTVKQKG--KAAVKDDE--WRVEER
LAHALVKGLTDYIDQDVEEARQKSVRPLDVIEGPLMAGMNIVGDLFGSGKMFLPQVVKSARVMKKAVAYLMPFMEAEKRSRANGKVLLATVKGDVHDIGK
NIVGVVLGCNNYEVIDLGVMVSCETILATAREQQVDMVGLSGLITPSLDEMVHVAKEMTRQGFTVPLLIGGATTSKATAVKGHATVHVLDASRAVGVVGS
LI-
>tr|D5MGY5|D5MGY5_9BACT B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase OX=671143 OS=Candidatus Methylomirabilis oxyfera. GN= PE=3 SV=1
--ELEQMLRH-RIVILDGAMGTMIQMHNLTEG-CNDLLAITQPAIIEAIHCQYLDAGADIIETNTFNSTSISMADRLLAYDLNLSGARAARSAVESPRFV
AGSIGPTNRTASSFRAVTFDRLVAAYTEQVRGLLDGGVDLLLVETVFDTLNCKAALFAIDQYRRVPIMVSVTIASGRTLSGQTVEAFWNSIAHMPLFSVG
INCAFGAKQMRPYLEELAQIASVFLSCYPNAGLPNA--FG--GFDETPAIMAADLGDFAKSGLNIVGGCCGSTPDHIRAIAKAVREYQPRVPPHP-QP-H
TRLSGLEPVTICPEVGFVNIGERTNIAGSAAFAKLIRSGEYEAAASIARQQVEGGAQIIDVNMDEAMLDAKAAMIQFLNLVACIARVPVMIDSSDWSVIE
AGLKCAQGKPVVNSISLKEETFIQRARLIKRYGAAVVVMAFDERGQADTLERKTEICARAYRILGTVGMPPQDIIFDPNILTVATGLEEAVDFIEATRWI
KANLYCKVSGGVSNVSFSFAVREAMHSAFLYHAVHAGLDMGIVNAGQLTVYADITVEDVLLNRRPDATDRLVEFAKTMKAQE--RAVVKDEA--WRVEER
LTHALVKGITDYIESDVEEARQRYDRPLQVIEGPLMAGMNLVGELFGSGKMFLPQVVKTARVMKKAVAYLLPFIEVERTKRTQRKVLMATVKGDVHDIGK
NIVGVVLGCNDYEVIDLGVMAPCDTILKTAREQQVDMIGLSGLITPSLNEMMHVAREMMREGLKIPLLIGGATTSRTTAVKDQPVVHVADASRAVVVAGH
LS-
>tr|Q1IYQ2|Q1IYQ2_DEIGD 5-methyltetrahydrofolate--homocysteine methyltransferase OX=319795 OS=Deinococcus geothermalis (strain DSM 11300). GN= PE=3 SV=1
--DIRAHARE-RILVLDGAWGTMLQRAGLTEG-NFDLLQLTRPDVIQGVHRAYFEAGADIASTNTFNSTAISQADGTLVRAMNEAGARLAREVADEPRWV
AGSVGPTNRTATPFRNVTFDDLVAAYLEQLEGLIAGGADLILIETVFDTLNAKAALFACEEAKRLPIMLSGTITSGRTLSGQTPEAFVISTEHADLFSVG
LNCALGADLLRPHLRAIAANTAALVSVHPNAGLPNA--FG--EYDETPEHTAAVLRSFAEEGVNIVGGCCGTTPDHIRAIAAAVADLPPRTAPRL-PP-Y
LRLSGLEALTISPETNFVNVGERTNVTGSPKFAKAILAGDYDAGLKIARQQVQNGAQLVDVNFDEGMLDGEAAMVKFLNLLAGISRVPLMLDSSRWEILE
AGLKRVQGKCVVNSISLKEAKFLERGRLLRRYGAAAVVMAFDEQGQADTLERRIEICSRAYRLLEQAAFPPQDIIFDPNVLTVATGIEEALDFIEATRWI
KANLGALVSGGISNVSFSFHVREAMHAVFLYHAIRAGLDMGIVNAGMLAVYEDIEVEDVILARRPDATERLIQLAESYKDV---REAGAQSA--WRVAER
LKHALVSGITDYVVEDAEEAYQLLGSPLAVIEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKRAVAHLTPYLEAQKQGGGKGKVLLATVKGDVHDIGK
NIVGVVLACNGYQVTDLGVMVPAEKILDTAQELGADVIGLSGLITPSLDEMVNVAREMTRRGLQTPLLIGGATTSRATAVKTGTVVHVLDASRAVGVVGD
LL-
>tr|F4KQJ4|F4KQJ4_HALH1 Methionine synthase OX=760192 OS=/ O). GN= PE=3 SV=1
----REQLKQ-RILVIDGAMGTMIQRYKLGEG-NNDLLSITQPQIIEEIHRAYLEAGADIIETNTFSGTSIAQADEMYVYDLNYYSAQVAKKAADDPRYV
AGAMGPTNRTASPYRAVTFKELKEAFYEQAKGLIEGGVDLLLLETIIDTLNVKAALFAIEDLYRIPVMVSGTITSGRILSGQTAEAFWISVSHVPLLSVG
LNCALGAEEMRPYLEALSNIADTFVSAYPNAGLPNE--FG--QYDQSAEEMQVYIRDFAASGVNMIGGCCGTTPDHIRAMVEAVKGLPPRQIPVS-PG-Y
TMLSGLEPLIIRPETNFVNVGERTNVTGSRQFARLIREGKYNDALIVAQQQVEAGAQMIDVNMDEGLLDSEKAIVEFLNLMMSIAKLPIMIDSSKFSVIE
AGLQCVQGKCVVNSISLKEESFIHHAKLVRRYGAAAVVMAFDEDGQADTIERKVSICERAYKILQQVGFKPQDIIFDPNIFAVATGIDEAIYFIEATRQI
KQRCGAKISGGVSNISFSYPVREAMHSAFLYHAIQAGMDMGIVNAGMIEVYANIPVEDVLFNRRNDATERLTEFAESIKNDGG-RVLQKDLA--WRLGER
ITHALVKGITDYIDEDTEEARQQFPHALNVIEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKKSVAYLTPFIEEEKASTK-GKILLATVKGDVHDIGK
NIVGVVLACNNFDIVDLGVMVPADKILKAAKEQNVDIIGLSGLITPSLDEMVHMAKEMERLGFTLPLLVGGATTSKTTAVKSGPVIHVLDASRSVGVAAA
LL-
>tr|F0SLW7|F0SLW7_PLABD Methionine synthase (B12-dependent) OX=756272 OS=NBRC 103401 / IFAM 1448). GN= PE=3 SV=1
--TFDALLED-RILLLDGAMGSMILDHRPTEN-ANDVLCLTQPDLIRKLHREYFEAGSDIVESNTFNANVISMEEGLYTYEINKRAIELAKEVADEPRFV
AGSIGPTKVQLSATRPVTYDQMVTSYREQINGMIDGGVDILLPETSFDTLNTKACLFAISQIIFLPVMVSGTIF-GRSLTAQTVGAFYTSVSHFPLFSVG
LNCALGPKQMRPFVEELAKIAQCRISCYPNAGMPDG--MG--GFDSSPQEVAAALREFAQDKVNLVGGCCGTTPDYIREIGKQTSDLKSRAYPAY-PR-H
SSYSGLERYEVRPETNFLMVGERTNVTGSRKFARLIREEKYDEALSVAREQVEAGANIIDVNMDEGLLDSVACMRKFLWLISDIS-VPIMIDSSNWEVIE
EGLKCVQGKPIVNSISIKEARFIAQAKKIRQYGAAVVVMAFDEQGQADTADRKVEICKRAYKILEQVGFPPEDIIFDPNILTVGTGMEEAVEFFEAVRRI
KQECGALTSGGVSNVSFSFVVREAMNAAFLYHAIQAGLDMGIVNASQLEVYEEIDIEDVLLNRREDATERLLEYADKIKDQN--QDPATAKKVEWRVEER
LQHALLKGITDYIDEDTAEALEKYGRPLNVIQGPLMDGMNVVGELFGTGKMFLPQVVKSARVMKKSVAYLTPFMEAEKAGA-RGTFLIATVKGDVHDIGK
NIVAVVLRCNNFDVIDLGVMVPADKILDTAVEVGADVIGLSGLITPSLEEMVAVAQEMKRRGMTTPLLIGGATTSAKTAVKDHIVAHVGDASLSVPVVES
LI-
>tr|Q3B628|Q3B628_PELLD Methionine synthase (B12-dependent) OX=319225 OS=273)). GN= PE=3 SV=1
--TLRELLRE-RILVLDGAMGTMIQRHKLTEG-NNDILVLTRPDIIYQIHCDFLEAGSDIIETNTFNANPISQGDGTLIKELNLEASRLARKAADSPRFV
AGSIGPTNKTLSPYRAVSFRDVVDNYLLQLEGLMEGGVDVLLVETVFDTLNCKAALFAIEEFKRVPVMVSGTVVSGRTLSGQTTEAFWISIAHMDLLSVG
LNCALGSKQMRPFIEAISTVAESFVSVYPNAGLPNE--FG--EYDDSPEYMADQIAGFAESGVNIVGGCCGTTPGHIKAIADAVVALQPRKRPTA-SH-E
LQLSGLEPLRVNSTTGFINVGERTNVTGSKKFARLIREGNYDEALSIARQQVESGAQVIDVNVDEGMLDSEKVMQEFLNLIASIAKVPVMIDSSKWSVIE
KGLQCVQGKSIVNSISLKEEPFRQRAAKILEYGAATVVMAFDEAGQADSLERRKEICGRAYRILEEVGFPPEDIIFDPNVLTVATGIEEALDFIESVRWI
KESLHAKVSGGISNVSFSFPVREAMHAAFLYHAIQAGLDMGIVNAGQLAIYEDIDVEDVLLNRRSDATERLVSFAETIRDGG--EKTEAKAE--WRVVER
LRHALIKGIVEYIDEDTEEARKLYPSPLQVIEGPLMDGMNAIGDLFAEGKMFLPQVVKSARVMKRSVAWLIPFIEEEKRKAA-AKILLATVKGDVHDIGK
NIVSVVLSCNNYEVIDIGVMMPCEKILEAAVREKADIIGLSGLITPSLDEMVHVAKEMERLGMKIPLILGGATTSKITAVKSGPVVQVLDASRSVPVAGS
LL-
>tr|H6L831|H6L831_SAPGL B12-dependent methionine synthase OX=984262 OS=Saprospira grandis (strain Lewin). GN= PE=3 SV=1
----HERIEQ-QILVIDGAMGTMLQQYKLQEG-NNDLLSITQPHLVTEVHKAYLDAGADIIETNTFNATAISQEDDMLVYELNYASAQCARAAVDAFRFV
AGAMGPTNRTASPYRAINFEQLRAAYYEQAKALAEGGADLFLVETVFDTLNCKAALFAIDQYIAYPVMVSGTITSGRTLSGQTVEAFWLSVSHANLFSVG
LNCALGAAEMRPHIEALSNIAHCYISAYPNAGLPNE--MG--EYDQTAQEMGLLIEDFAQSGINIVGGCCGTSPAHIRRMAEVVAQLPVRKKPAP-MQ-L
SAYSGLEPLIVRPGFNFINVGERTNVTGSRKFARLIKNGNYEEALSVAQQQVEGGAQIIDVNMDEGMLDSVEAMSYFLNLIASIARLPIMIDSSKWEVIE
AGLRCVQGKAIVNSISLKKAAFVQQAKLVRRYGAAAVVMAFDEVGQADTMERKVEICSRAYKILEEVGFPPQDIIFDPNIFAIGTGIEEGVDFIEATKEI
KRRMLVKISGGVSNLSFSFIVREAIHSAFLYHAVQAGMDMGIVNAGMIEVYEDIPVEDLLFNRRPDATERLTDYAEQLKGQGG-KKRQEDLS--WRVEDR
LAHALVKGITKFVIEDTEEARQQYSSPLEVIEGPLMSGMNIVGDLFGAGKMFLPQVVKSARVMKQAVAHLTPFIEAEKSSAK-GKILLATVKGDVHDIGK
NIVGVVLACNNFEIIDMGVMVPANEILKKAQEEQVDILGLSGLITPSLDEMVYVAKEMQRLGMQMPLLIGGATTSKTTAVKSGPTVHVLDASRAVTVAAS
LL-
>tr|D2MH73|D2MH73_9BACT 5-methyltetrahydrofolate--homocysteine methyltransferase OX=700750 OS=Candidatus Poribacteria sp. WGA-A3. GN=POR_0022 PE=3 SV=1
--ELKDRLHR-RILVLDGAMGTMIQKRNLSEG-NNDLLVLTQPELIGSLHREYLEAGADMIETNTFNSTAISMADQMLAYELNVAGAAVARKAADAPRFV
AGVLGPTNRTASPFRAVTFEQLRQAYAEQVRGLVEGGSDLLLVETIFDTLNAKAAFFAIDQYVPIPVMVSVTITSGRTLSGQTIEAFWHSIADADPFSVG
INCALGAKQMRPYIEELSKRAPVYITCHPNAGLPNA--FG--GFDETPERMAEDLREFAGNGLNIVGGCCGSTPEHIAAIAEAVCDLPPHAVVEP-DH-D
TRLSGLEPLTIRPELNFVNIGERTNVTGSPKFSRLIREDQFEEALAVARQQVEGGAQLIDVNMDEAMLDSENAMVRFLNLIASICRVPLMVDSSKWSVIE
AGLQCVQGKGVVNSISLKEEKFKEQARLVKRYGAAVVVMAFDETGQADTIDRKVEICTRAYKILEDMAFPPQDIIFDPNILTVATGIEEAVNFIEAVRQI
KATLHCKTSGGVSNISFSFVVREAMHSAFLYHAIKAGLDMAIVNAGQLGVYEEIPVEDVLLNRRPDATERLVDFAETVQQQG--KAVVKADA--WRVEAR
LSHALVKGIVDYIDEDVEEARQQYDKPLKIIEGPLMDGMNVVGELFGAGKMFLPQVVKSARVMKKAVAYLLPFMDQEKESRAQGKVLLATVKGDVHDIGK
NIVGVVLGCNNYEVIDLGVMVPCEKILTKAKEEQVDMIGLSGLITPSLEEMAYNAKEMARQGFDVPLLIGGATTSKATAVKPEPVVHVTDASLAVNVVRQ
LL-
>tr|Q3APY1|Q3APY1_CHLCH Methionine synthase (B12-dependent) OX=340177 OS=Chlorobium chlorochromatii (strain CaD3). GN= PE=3 SV=1
-------------------MGTMIQRHKLKEG-NNDMLVLTQPDIIYTLHCAFLEAGSDIIETNSFNANPISQADSALVHELNVEACRLARRAADEPRFV
AGSIGPTNKTLSPYRAVTFREVVDNYLVQLEGLREGGVDLLLVETVFDTLNCKAALFAISEIWRVPVMVSGTVVSGRTLSGQTTEAFWSSVCHLELLSIG
LNCALGSKQMRPFIEAMANVAESYVSVYPNAGLPNE--FG--QYDDSPEYMATQIADFATSGVNIVGGCCGTTPDHIKAIAEAVQTISPRKRPTK-KH-E
LLLSGLEPLVVNHTTGFINIGERTNVTGSKKFARLIKEGNYDEALSIARQQVENGAQVIDVNVDEGMLDSEKVMKEFLNLIASISRVPIMIDSSKWSVIE
SGLQCVQGKGIVNSISLKDELFRERARKILRYGAATVVMAFDEQGQADNLQRRIEICQRAYNILNEVGFPPEDIIFDPNVLTVATGIEEAVDFIESVRWI
KENLHAKVSGGISNVSFSFPVREAMHAAFLYHAIRAGLDMGIVNAGQLAIYEDIEVEDVLLNRRADATERLVSFAETIATGG--EKVEAKAE--WRVAER
LRHALIKGIVEHIEEDTEEARQLYPSPLQVIEGPLMDGMNAIGDLFAVGKMFLPQVVKSARVMKRSVAHLIPFIEAEKKSAQ-AKVLLATVKGDVHDIGK
NIVAVVLACNNYEVIDIGVMMPCEKILEAVEREKADLLGLSGLITPSLDEMVHVAAEMERRGMKIPLLIGGATTSRMTAVKSGAVVQVLDASRSVPVVNS
LL-
>tr|B6YR37|B6YR37_AZOPC Cobalamin-dependent methionine synthase OX=511995 OS=Azobacteroides pseudotrichonymphae genomovar. CFP2. GN= PE=3 SV=1
--NISQLLQE-RILLLDGGMGSMIQNYRLKEG-NSDILCITRPDIIQSIHEAYLEAGADIIETNSMNMTAISMADGIHVESLNKAAATIAKEVAQKPRFV
AGSIGPTNKTSSPYRNITFTELYKAYCEQIAALIFGGVDILLVETAFDTLNVKAALMAAEDEKELPLMLSYTLSSGRILSGQTLEAVLESISHINLLSIG
LNCSFGARTMKPFLKKLGQIAPCYVSAYPNAGLPNA--FG--KYNETPEMMAEQIREYIDESVNIVGGCCGTTPQHIAAIARLVNECKRSRVPVI-KSTE
L-LSGLEILEIKKGSNFVIIGERCNVAGSRKFLQLIREKNYEEALKVAQKQIENGAQVLDVNVDDGLLNGIQEITTFLNLITSIASIPIMIDSSDWNVIE
AGLQCLQGKSIVNSISLKEDDFLDKAQKVKSYGAAVIAMAFDEKGQASDFNRKITVCARMYELLSKIDFQPSNIIFDPNILAIATGIEEAVDFIQAIKWI
KKHLFAKVSGGISNLSFSFYLRQAIHSVFLSHAINAGMDMGIINPMENFMQENISIEDILFNRSSHALENLTEYIRKQTSNEK-SSKKKN-E--WRVTER
LKYAVIKGIDDFLKTDLQEAIKIYPQVMDIIDQPLMEGMNTVSNLFGKGQMFLPQVVKTARIMKKAIDILQPYLEANKKVKS-GKILFATVKGDVHDIGK
NITSTILSCNNYEVIDMGVMVPSEEIVRKAKEYHVDIIALSGLITPSLQEMSIVASEMEKAGLSLPLLIGGATTSKLTALKRGAVIHVSDASKAVPTANH
LV-
>tr|I7A4W8|I7A4W8_MELRP Methionine synthase OX=1191523 OS=Melioribacter roseus (strain P3M). GN= PE=3 SV=1
--VLKDILNR-RIMILDGAMGTMIQRHKLSEG-NNDILVITRPEIIKSIHREYLEAGADIIETNTFNSTSISQADGAYVYELNYRAARIAREAADEPRFV
AGALGPTNKTLSPYRAITFDEMKEAYKEQAKGLIEGGADILLLETVFDTLNAKAALFGIMELIELPIMISGTVISGRTLSGQTTEAFWISISHTNLLSVG
LNCSLGPAQMRPFISELSEIADVYVSIYPNAGLPNE--FG--QYDESPEAMLKILEEYAAEGFNIVGGCCGTTPEHIKAFAEIADKYPPRKIPNT-EP-Y
LRLSGLEPLVFRPDTNFVNIGERTNVAGSRKFARLIREGKYEEALSVAREQVENGAQIIDVNMDEAMINSEEAMAKFLNLISSIARVPVMIDSSKWSVIE
AGLKCLQGKGIVNSISLKEEAFKEQAKKILKYGAAVIVMAFDEEGQADTFERKISICKRAYEILKEVGFPPQDIIFDPNIFAVATGIEEALDYIEAVRWI
KNNLLAKVSGGVSNVSFAFAVREAMHSAFLYHAIEAGMDMGIVNAGQLAVYEEIEVEDVLLNRRPDATERLIEYANSVDKTK--RKEVKDEQ--WRVEER
LKHALIKGIVEFIEEDINEALKIYKHPLSIIEGPLMEGMNVVGDLFGAGKMFLPQVVKSARVMKKAVALLIPYIEADRSSNA-GTILLATVKGDVHDIGK
NIVGVVLGCNNYKIIDLGVMVPADKIIQTAIDEKADIIGLSGLITPSLDEMVHVAKEMERRKMNLPLLIGGATTSRITAVKSGSVIHVLDASKSVNVASS
LL-
>tr|K2BVG1|K2BVG1_9BACT Uncharacterized protein OX=77133 OS=uncultured bacterium. GN= PE=3 SV=1
--QLLELLKS-TILIIDGAMGTMIQTYHLTEG-NNDLLCLTQPHIIHAIHAAYLKAGADIIETNTFGATSIALSDQLLAVEINYQAAKLARAACDEPRFV
AGAIGPTNRTASPARNISFDELVLAYTEATDGLVKGGVDIILIETIFDTLNAKAAIYAVKKYIELPIMISGTITSGRTLSGQTIEAFWHSVMHANPIAIG
INCALGAEDMRPYVQTLSKIADTYVSVYPNAGLPNE--LG--EYEQSPERMSELIFEFAQNGINVAGGCCGTTPQHINAIAEKIKNTKPRKIPDI-KP-Y
CRLSGLEPLTLYPDSNFINVGERTNVTGSAKFKKLILEKKYEEALHVARQQVEQGAQIIDINMDEAMLDSADEMRTFLNLVASISRVPIMVDSSKWSVIE
TGLQCLQGKGIVNSISLKEVAFIACAKKILYYGAAVVVMAFDEQGQADTRDRKIEICKRAYVILNQVGFKPSDIIFDPNIFAIATGIDAAVDFIEATVEI
KKHCHALISGGVSNVSFSFPVREAIHAVFLYHAIRAGLDMGIVNAGQLPIYQDIPVEEVVLNRKPDATEKLLEIAQTVMSTD--KTQQKD-S--WRVNER
LTYALVQGITEFIDVDTEAARLSASYPLAVIEGPLMDGMNQVGELFGDGKMFLPQVVKSARVMKKAVAYLIPYIEAEKKASARGKILMATVKGDVHDIGK
NIVGVVLQCNNYDVIDLGVMVPCEKIIETAKKENVDMIGLSGLITPSLDEMCFVASELQRTDFTIPLLIGGATTSRVTAVKLHDVIYVKDASRAVGVAAK
LL-
>tr|K1ZJ35|K1ZJ35_9BACT Uncharacterized protein OX=77133 OS=uncultured bacterium. GN= PE=3 SV=1
--YLEKQLKQ-RIFILDGAMGTMIQRHRLQEG-HNDLLCLTQPDIITDIHKAYLDAGADFIETNSFNANAISLLDHMLAYEINFAAATLARRMADEPRFV
IGILGPTNRTASPFRNVSFDQLVTAYMEAVRGLVDGHVDILMIETIFDTLNCKAAIFAIEKYVRLPVMISGTITSGRTLSGQTTTAFWHSVGHAKPMSIG
LNCALGAEALRPYVRELSTIADTYVSLHANAGLPNA--FG--EYDETPQDTARVVSEFAREGVNIVGGCCGTTPEHISVLAEAVKIIPPRLIPVI-QK-A
CRLSGLEPLTIDKTSLFVNIGERTNVTGSTRFADLIRNENYQAALDVAREQVLNGAQAIDVNMDEGMLDAEAVMVKLLLLIASIARVPIMIDSSKWSVIE
AGLKCIQGKGIVNSISLKEAAFLEKARLAYQYGAAVVVMAFDEQGQADNEERKLAICKRSYDLLNTVGFPPEDIIFDPNIFAIATGIEEGLDFIRATKRI
KENLHALVSGGVSNISFSFAIREVIHAVFLYHAIQAGMNMGIVNAGSLAIYADIPIEDVLFNRRSDATDRLLEVADSLKSQV--KTSTED-S--WRVSER
LSHALVKGVTQFIIEDTEEARVLLGSSLRVIEGPLMDGMNVVGDLFGSGKMFLPQVVKSARVMKQSVAYLTPFLEKEKTAHVKGKMVIATVKGDVHDIGK
NIVGVVLRCNNYEVIDLGVMVSCEKILETARQESVDLIGLSGLITPSLEEMIHVASEMERLQFTIPLLIGGATTSRATAVKSGATVHVVDASRAVGVASQ
LL-
>tr|C6XUY2|C6XUY2_PEDHD Methionine synthase OX=485917 OS=Pedobacter heparinus (strain ATCC 13125 / DSM 2366 / NCIB 9290). GN= PE=3 SV=1
--DIRKELEK-RILIIDGAMGTMIQRYTLTEG-NNDMLSITRPDVIKEIHTEYLKAGTDIIETNTFSTQRISLADQMLAYEMSFEGAKIAKEAVNEKCFV
AGAVGPTNRTLSPFRAITFDELVEAYDEQVRGLVDGGADLLLIETIFDTLNAKAAIFSIKKYRKIEIMISGTITSGRTLSGQTAEAFLNSVMHANPLSIG
FNCALGAKDMRPHIEELSAKAGCYVSAYPNAGLPNE--FG--AYDEMPHETAHLVEDFIQHGVNIVGGCCGTTPEHIGCIAKKAKNVAPRKIPHI-EP-Y
LRLSGLEPVTITPESIFVNIGERTNITGSPKFSKLILGGDFEAALAVARQQVEGGAQVIDVNMDEGMIDSEASMTKFLNLIASISKLPIMVDSSKWTVIE
AGLKCLQGKGIVNSISLKEDKFRESARKIMTYGAAVVVMAFDELGQADNFERRKEICKRSYDILDEIGFPAQDIIFDPNILTVATGLEEAVDFINATRWI
KENLYAKVSGGVSNISFSFTVREAMHSAFLYHAIKAGLDMGIVNAGMLEVYQEIPVEDVLLNRRDDATERLVEFADTIKSKG--KEIVRDEE--WRVEER
LSHALVKGIIEYLDADVEEARQKYARPIEVIEGPLMDGMNIVGDLFGAGKMFLPQVVKSARVMKKAVAYLLPFIEQEKQSSA-GKILMATVKGDVHDIGK
NIVGVVLACNNFEIVDMGVMVPAQDIIKKAKEINADIIGLSGLITPSLDEMVHFAKEMEREGFTIPLMIGGATTSRIAAVKSGPAIHVLDASRSVTVAST
LM-
>tr|C9RQ92|C9RQ92_FIBSS Methionine synthase OX=59374 OS=Fibrobacter succinogenes (strain ATCC 19169 / S85). GN= PE=3 SV=1
--TLREAFES-KMMLLDGGMGSVIQTY----GANNDMLSIEKPEIILDIQRRYVDAGVDCLTTNTFSSQRVSQHEHQRIAEMNRASVKIAKAAEEGKVYI
LGDVGPTSKMLSESRAITFDELEDAYLEQISVLMEEGVDAILIETIFDTLNAKAALSAYSKAAKKPVMLSMTVSSGRTLSGQTVEAFAVSVMHMHPLSIG
LNCGLGADGMVPYLRRMGAIAPCYLSCHPNAGLPNQ--FG--GYDDTPEDMVRLMRVYLDDKVNMIGGCCGTTPEHIAAMRQMLDALPA-DYKRR-EPAV
TRLAGLEPLQVCNADDFVKVGERCNVAGSKKFLRLINEKNYEEALDIARKQVDDGADVIDVNMDDGLLDATAEMRTFLNLIASVSRVPIMVDSSRFEVIE
EGLKCIQGKSIVNSISLKEKAFIEHALTVKRLGAAVIVMLFDEEGQATNYERRVQIASRAYDIMKQLHFDPSDIIYDPNVLTVATGMAEAIDFIRAVRWI
MDNLGVRISGGLSNLSFAFYLREAMHTTFLHYAIPNGMGMAIMNPSAIIKYKTIPITEVIFNTEPEASEELIEIASRMTSTGSATSDANEKAD-AKPEER
LQEALLKGTSTTLQPDLMELINRGDSPVGIISGPLMDGMNEVGRRFGEGKMFLPQVVKTARTMKKAVEILQPYIEAGK-ASSRGKIVIATVKGDVHDIGK
NIVSVIMACNGYDMVDLGVMVPEDVIVKAAIENKADILSLSGLITPSLEEMCTVAKAMQAAGQRIPIIVGGATTSPTTAVKDGPVFHVRDAASNPGLAQK
LL-
>tr|E7C3S7|E7C3S7_9BACT Methionine synthase I, cobalamin-binding domain OX=723607 OS=uncultured Planctomycetales bacterium HF0200_11L05. GN= PE=3 SV=1
--SFNKKLKE-KILVIDGAMGTEIQSKKLSEG-NNDLLNLTQPEIIKEIHKSFLDKGCDFIQTNTFNSSSISQKDDLKAYDLNFMGAKIAKEAISENAWV
IGSIGPTNTTASPKRNILFDELVISYRECIDGLLEGGVDFLMFETIFDTLNAKAGIFAYLDKKKIPLMISGTITSGRTLSGQTAEAFWTSVKHANPCSIG
FNCALGAEQLRPHLISLNKISDIPISLHPNAGLPNE--MG--EYDETPSHMASIIKEMAESSLNIVGGCCGTTPDHIEAISYAIKGIKP-KKLSA-SKP-
--FSGLETLVLNDNSLFINIGERSNVTGSAKFARLIKEKNYAEALEVAKEQVELGAQMIDVNMDEGMLDSLKEMDHFLKLVATISKVPIVIDSSKWEVIE
SGLKVIQGKAIVNSISLKEDNFIKVAKLCLKYGAAIIVMAFDEKGQADSLKRRKEICRRSYEVLKVVKYPPQDIIFDPNVFAVATGLEEAKDFIDACAYI
KEEFLTSISGGISNVSFSFAVREAMHSVFLYHAINKGLTMGIVNAGQLAVYEDINVEDVILNRREDATERLVDEATKFL-KQT-RKTTDE-K--WRINER
INHALVQGINKYIIEDVEEARCKSNSPVEVIEGPLMDGMNIVGDLFGDGKMFLPQVVKSARVMKEAVAYLVPYLEEEKEQTN-GKIVMATVKGDVHDIGK
NIVTVVLQCNNYEVINLGVMVPAEQIIDTAISENADLIGLSGLITPSLDEMIGVVQELTRRKMNIPVLIGGATTSKATALKKTGFIHVLDASRSVGVVQN
LL-
>tr|F0SDG7|F0SDG7_PEDSD Methionine synthase (B12-dependent) OX=762903 OS=10337 / NBRC 100064 / NCIMB 13643). GN= PE=3 SV=1
--DIREELKK-RILVIDGAMGTMIQNYKLTEG-NNDLLNITRPDIIKAIHKEYLLAGADIIETNTFSTQRISMADHMLSYELSYEGAKIAKEVATEPRFV
AGAIGPTNRTLSPFRAISFDELESAYYEQVRGLVDGGADLLLVETIFDTLNAKAAIFAIKKYRKIEIMISGTITSGRTLSGQTTEAFWNSMRHGDLLSIG
LNCALGAKDMRPYIQELSELADVFVSAYPNAGLPNE--FG--QYDETAEQTAGLLDDFLSSGLNMVGGCCGTTPQHIKRIAETAAKYTPRKIAQP-ER-W
MRLSGLEAVNIKPDSIFVNIGERTNITGSPKFSKLILSGDYETALSVARQQVEGGAQVIDVNMDEGMLDSVAAMTKFLNLISSICKVPVMVDSSKWEVIE
AGLKCLQGKGIVNSISLKEEKFKESARKIKQYGAATVVMAFDEKGQADNYERRIEICKRSYDILNEVNFPAEDIIFDPNILTVGTGLEEAVDFINATRWI
KENLYAKVSGGVSNISFSFPVREAMHSAFLFHAIKAGLDMGIVNAGMLEVYEEIEVEDVLLNRRPDATEILVDFAETVKNKG--KVIVKDEE--WRVEER
LSHALVKGIVAHIDEDVEEARLKYARPLEIIEGPLMDGMGVVGDLFGSGKMFLPQVVKSARVMKKAVAILLPYIEAEKESSA-GKILMATVKGDVHDIGK
NIVGVVLACNNFEIIDLGVMVPATTILEEARKHNVDIIGCSGLITPSLDEMVHIAKEMEREGFKIPLMIGGATTSRITAVKSGPVIHVLDASRSVTVCSN
LL-
>tr|I0H1N3|I0H1N3_ACTM4 Putative 5-methyltetrahydrofolate--homocysteine S-methyltransferase OX=512565 OS=/ JCM 3121 / NCIMB 12654 / NBRC 102363 / 431). GN= PE=3 SV=1
--TLRELLAE-RILVLDGAWGTMLQGAKLTPG-DPDLLILTRPDVILDVHRQYLAAGADITTTNTFTATSIAQADGLLVREMNVQGARLARQAADEPRFV
AGSVGPLNVTLSPYRAVTFDKVKATYAEQIAALAEGGVDLLLVETIFDTLNAKAAIAAAHEVPELPLWISVTIVSGRTLSGQTVEAFWRSIERAKPLVVG
VNCSLGATEMRPHVTDLARLSDVYVASHPNAGLPNA--FG--GYDETPAETSALVAGFASDGVNIVGGCCGTTPAHIGAIATAVAGMTPRVIDPP-AP-T
TRFSGLEPFEIGPDTGFVMIGERTNVTGSAKFRRLIEAGDHQAAVDVALEQVRGGANLLDVNMDADLLDSEQAMTTFLNLIATVARIPIMIDSSKWSVLE
AGLKCVQGKGVVNSISLKVDQFLTQARRIRDFGAGVVVMAFDEHGQADTADRKVAICARAYDLL-EDGFDPNDIIFDPNVLAVATGIAEAKAFIDALPRI
KERCGARTSGGISNLSFAFVVREAMHSAFLFHAVKAGLDMGIVNAGQLAVYQDIPVEDVLFDRREDATDRLVTFASTVTGS---AKREVDLS--WRVGER
LTHALVHGIVDFIEEDTEEARQELPRPLEVIEGPLMDGMKVVGDLFGSGRMFLPQVVKSARVMKRSVAYLEPFMEAEKEGRGQGKVVLATVKGDVHDIGK
NIVGVVLGCNNYDVIDLGVMVPAAKILETAVAENADVIGLSGLITPSLDEMVAVGAEMQRRGMNLPLLIGGATTSKQTAVREGSTIHVLDASRVVGVVSN
LL-
>tr|C4RNB1|C4RNB1_9ACTO B12-dependent methionine synthase OX=219305 OS=Micromonospora sp. ATCC 39149. GN=MCAG_05523 PE=3 SV=1
--ALRRLLGE-RIAVLDGAWGTMLQGARLSPG-DPDLLNLTRPDLILDVHRQYLAAGADITTTNTFTATSIGQADGLLARDMNVRGAQLARQAADE-RFV
AGSVGPLNVTLSPYRAVTFDDVKDAYAEQMAALAEGGVDLLLVETVFDTLNAKAAIAAAREAPRLPLWISVTVVSGRTLSGQTVEAFWRSIAHAEPLVVG
VNCALGAAEMRPHVAELSRLAGSYVAAHPNAGLPNA--FG--GYDQTPEEIGALLGEFASDGVNIVGGCCGTTPPHIAGIAAAVRGVAPRPVARE-VP-A
TRFSGLEPFTIGPDTGFVMIGERTNVTGSARFRRLVEADDYQAAVDVAVEQVRGGANLLDVNMDADLLDSEQAMVTFLNLIATVARIPIMIDSSRWSVLE
AGLKCVQGKGVVNSISLKEEPFLAQARAIRGYGAGVVVMAFDEQGQADTSERKVQICGRAYDLLGEAGFAPEDIIFDPNVLAVATGMAEAKEFIDALPLI
KARCGARTSGGISNLSFAFVVREAMHSAFLFHAVRAGLDMGIVNAGQLSVYENIPVEDVIFDRRPDATDRLVAFASTVTGS---TKREVDLS--WRVAER
LKHALVHGIVDHVEADTEEARLLLDRPLDVIEGPLMDGMRVVGDLFGAGKMFLPQVVKSARVMKRSVAYLEPYMSKERAGQGQGKVVLATVKGDVHDIGK
NIVGVVLGCNNYEVIDLGVMVPTARILDTAVAEGADAIGLSGLITPSLDEMVAVATEMQRRGLRMPLLIGGATTSRQTAVREGPTVHVLDASRVVGVVSD
LL-
>tr|K0JZN6|K0JZN6_SACES Methionine synthase OX=1179773 OS=NBRC 15066 / NRRL 15764). GN= PE=3 SV=1
--ALRQLMDR-RVAVLDGAWGTMLQNAGLTPG-DPDLLNITRPDVILDVHRQYLAAGADITTTNTFTATGIAQADGLLVRDMNVQGARLARQAADEGRFV
AGSVGPLNVTLSPYRAVTFDQVKASYAEQIAALDEGGVDLLLVETIFDTLNAKAAMSAAREVPHLPLWISVTIVSGRTLSGQTVEAFWRSIEHAEPLVVG
VNCSLGATEMRPHVAELARIASAYTAAHPNAGLPNA--FG--GYDQTPDETAELLHEFADAGVNVVGGCCGTTPEHIARIAAAVKDLTPREATGP-AP-A
TSFSGLEPFTIGADTGFVMIGERTNVTGSKRFRRLIEADDHQGAVDVALEQVRGGANLLDVNMDADLLDSEEAMTTFLNLIATVARIPIMIDSSRWSVLE
AGLKCVQGKGVVNSISLKEEPFLAQARAIRDFGAGVVVMAFDEQGQADTADRKVSICGRAYDLLQQVGFRPEDIIFDPNVLAVATGIAEAKEFIEALPRI
KQRCGARTSGGISNLSFSFVIREAMHSSFLLHAVRAGLDMGIVNAGQLAVYEDIPVEDVLFDRRPDSTDRLVAHAETVKGS---TKRVADLA--WRVEQR
LSHALVHGIVDFIEEDTEEARQNAARPLEVIEGPLMDGMKVVGDLFGAGKMFLPQVVKSARVMKRSVAYLEPYMEAEKERRGPGKIVVATVKGDVHDIGK
NIVGVVLGCNNYEVIDLGVMVPSSVIIDTAVAEGADAIGLSGLITPSLDEMVTVASDMQRRGVKLPLLIGGATTSRQTAVREGTTVHVQDASRVVGVVSE
LL-
>tr|G0GCR7|G0GCR7_SPITZ Methionine synthase OX=869211 OS=Spirochaeta thermophila (strain ATCC 700085 / DSM 6578 / Z-1203). GN= PE=3 SV=1
--EL---LKE-RILILDGAMGTMIQRYHFSEG-NHDLLALTRPHVIEEIHRAYLEAGADIIETNTFNATRVSQREGTLVERINLEAARLARRVADEPRFV
AGVLGPTSKTLSPFRELSFGELEEDYFGAVRALVEGGADLILIETVFDTLNAKAALAAVARFRAVPVMLSATISAGRLLSGQTPRAFLHSVLHGRPLSVG
FNCAFGPEMMRPHLKAIQD-APCAVSVHPNAGLPNA--LG--EYDQGPDQMAATLALYAREGLNIAGGCCGTTPDHIRAIAEALEGIPPRPIPSP-RPVA
V-FTGLEVLD-QEEAGFILVGERTNVAGSARFRRLLREERWEEALEVARAQISAGAQMIDVNVDDPLLDPPRFMRRFLSLAASVARVPVMIDSSDWEVLR
AGLESLQGKGVVNSLSLKEEVFLERARVVREMGAAVLVMCFDEEGQAETFERKIAVAQRAYRLLEEVGIPPWEIVIDPNIFAIGTGMEEGLDYLEAVRWI
KEHLHARTSGGISNVSFAFGLRDAIHAVFLHHARAAGLDMAIVNPQRMMAYEEVPIEDLVFDRRRDATERLLEAARGFSGAGP-RVRGEDRA--WRVEER
LAYALKEGIQAYLVEDLEEAHRKAGSALGVIEGPLLTGMEEVGRLFGEGRLFLPQVVRAARVMREAVAILEPRLKAEQGKA-RGVVVLATVKGDVHDIGK
NIVKVVLECNGYRVVDLGVMVPPERVVEAARQ-GADAVGLSGLITPSLERMRETAEAIDRAGPAVPLLIGGAATSRLTALRRGPVIHVRDASEAVQVMGR
LL-
>tr|E8U945|E8U945_DEIML Methionine synthase OX=709986 OS=/ LB-34). GN= PE=3 SV=1
--ELLSIARE-RILILDGGWGTMLQRRGLTEG-NHDVLQLTRPDVIREIHRLYFEAGADITSTNTFSSTSIAQADGLLARALNVAGARLAREVADEPRFV
AGSVGPTNRTATPFRAVTFDDLAAAYEEAVEGLLEGGADLILIETVFDTLNAKAALFACEAVRRAPVMLSGTITSGRTLSGQTPEAFTVSTEHAPLFSLG
LNCALGADLLRPHLRALARSTDVLVSVHPNAGLPNA--FG--EYDETPEHTAGVLREFAEDGVNIVGGCCGTTPEHIRAIAKAVRDVKPRVAAPL-PR-Q
LRLSGLEAFTVTPEVNFVNVGERTNVTGSPKFSRAILEGDFDAGLKIARQQVVSGAQVIDINFDEGLLDGEAAMVRFLNLLAGIARVPIMLDSSRWSVLE
AGLKRIQGKGIVNSLSLKEAAFLAQARTIRRYGAAVVVMAFDEQGQADTLERRTEICARAYRLLQQAGFAGHDIIFDPNVLTVATGLPEALDFIEATRWI
KANLGALVSGGISNVSFSFAVREAMHAVFLYHAIRAGLDMGIVNAGMLAVYDDLDVEDVILARRADATERLIELAERFKGE---RSASSNAAS-WRVRER
LSHALVQGISDFVEVDAEEAYQLLGSPLAVIEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKRAVAHLTPYLEAEKAGSSKGRVVMATVKGDVHDIGK
NIVGVVLACNGFEVTDLGVMVSGERILDEAARLNADVIGLSGLITPSLDEMVNVAREMERRGLNTPVLIGGATTSRATAVRSGPVAHVLDASRAVTVVQD
LL-
>tr|B0N048|B0N048_9BACT 5-methyltetrahydrofolate--homocysteine methyltransferase OX=445970 OS=Alistipes putredinis DSM 17216. GN= PE=3 SV=1
--E----LEH-RILLLDGGFGTMIQQYGLDEG-CNDLLNLTRPETIREIHEKYLQAGSDVITSNTFNANSISLADGLEAYRINRVGAAIAREAADAPRFV
GGSMGPTSHTLSAARAFTFEQLSQAYYDQARGLMDGGVDLLMLETVFDALNAKAAIFAIESLMRLPVIVSGTLTSGRTLAGQTIEAFYTSVAHAEPLAVS
LNCSFGAKALLPYLERLAAVSEFRVAVYPNAGLPNV--MG--GYDETPAMFAADVEEYMRRGVNLVGGCCGTTPLHIFELAKIVNNYAPRPLPQR-RHVT
C-LSGLEQLRIVPEANFVNVGERTNVAGSAKFARLIREKNYEEALSVARAQVEAGAQIVDVCMDDGLIDGPEAMRDFLNLMGSIAAVPVMIDSSKWEVLE
TGLRVVQGKSVVNSISLKKQEFLHRARLIRRYGAAAVVMLFDEQGQADTYARKIEVAQRAYKLLD-DGFPAEDIIFDPNILAVATGIEAARDFIEAVRWI
KQNLHAKISGGVSNLSFAFAVREAMHSVFLYHAIQAGMDMAIVNPQMLQIYSDIEVEDVILCRRADAAERLTEYASQFTKT-T-QTQHTD-A--WRLGKR
IEYAMLKGVADYIEQDALEGYRTLGSPLAVIDRLLMPAMEVVGNLFGQGKMFLPQVVKTARVMKKAVAVLTPYIEQGSEKSA-GKVLVATVKGDVHDIGK
NIVAVVMACNGYTIRDLGVMVECPRIIDEAVAWGADAICLSGLITPSLEEMIHVCEELERRGLQIPVLIGGATTSDVTAVKSGPVIHADNASRNNKILGE
LL-
>tr|D8I1K8|D8I1K8_AMYMU 5-methyltetrahydrofolate--homocysteine methyltransferase OX=749927 OS=Amycolatopsis mediterranei (strain U-32). GN= PE=3 SV=1
--RLRELLDQ-RVAVLDGAWGTMLQGAGLTPG-DPDLLNLTRPDVILDVHRQYLAAGADITTTNTFTATSIGQADGLYVHEMNVRGAQLARQAADEGKFV
AGSIGPLNVTLSPYRAVTFEQVKASYAEQIAGLAEGGVDLLLIETIFDTLNCKAAIAAAREVPQLPLWISVTIVSGRTLSGQTVEAFWSSIEHAKPLVVG
VNCSLGAEEMRPHVEELSRIAGTYVACHPNAGLPNA--FG--GYDQTPEETAGLIGGFARDGVNLVGGCCGTTPAHIAKIAAAAKEAGPREVPAP-RT-H
MRFSGLEPFGIGADTGFVMIGERTNVTGSKRFRRLIESGDHQGAVDVALEQVRGGANLLDVNMDADLLESEQAMTTFLNLIATVARIPVMVDSSKWSVLE
AGLRCLQGKGVVNSISLKEEPFLAQARTIRNYGAGVVVMAFDEQGQADTADRKVAICGRAYDLLQKAGFAGEDIIFDPNVLAVATGISEAKAFIEALPRI
KERCGARTSGGISNLSFSFVVREAMHSAFLFHAVQAGLDMGIVNAGQLAVYEDIPVEDVLFDRREDATDRLVSFAENVKGS---TKRVVDLS--WRVGER
LSHALVHGIVDYIEDDTEEARQQLARPLDVIEGPLMDGMKIVGDLFGSGKMFLPQVVKSARVMKRSVAYLEPYMEAEKETGGQGKIVLATVKGDVHDIGK
NIVGVVLGCNNYEVIDLGVMVPAAKILDTAVTEGADAVGLSGLITPSLDEMVAVATEMQRRGLKLPLLIGGATTSRQTAVKDNVTVHVLDASRVVGVVSD
LL-
>tr|D4IP79|D4IP79_9BACT Methionine synthase (B12-dependent) OX=717959 OS=Alistipes shahii WAL 8301. GN=AL1_25320 PE=3 SV=1
--Q----LER-RILLLDGGFGTMVQGYGLQEG-CNDLLALTRPDVVREIHEKYLRAGADIIETDSFNANAVSLADRLCAYEISKVAAGIARSAADEPRFV
AGSVGPTNRTASAAREVTFAQLVEAYTDQVRGLVDGGADILLVETVFDTLNAKAALWAIDTLRAIPVMVSGTLASGRTLSGQTVEAFAVSVSHANLLSVG
LNCAYGAKQLLPYLERLAAVAGTRISAHPNAGLPNV--MG--GYDETPEMFAGDVGEYMRRGVNIVGGCCGTTPAHIFELSKISGDYAPRPVPAP-KHIT
T-LSGLEPLRIVPEANFINVGERTNVAGSARFARLIREANYEEALSVARAQVDAGAQIVDVCMDDGLIDGPAAMRTFLNLMASIARVPVMIDSSKWEVLQ
AGLEVTQGKSVVNSISLKEAEFLRRAAEIHRFGASAVVMLFDERGQADTFERKAEVAERAYKLLD-NGFPPEDIIFDPNVLAVATGIAEAKAFIDATRWI
KEHLHAKVSGGVSNLSFAFTVREAMHSAFLYHAIRAGMDMGIVNPQMLKVYSQIEVEDVILCRRADAAERLAEYAHGVQQT-A-QPQAPD-A--WRLGER
IAHAMLKGVADYVEQDALEGYEALGSPMAVIDTLLMPAMEQVGTLFGEGKMFLPQVVKTARVMKRAVAALTPYIEQGSAHNS-GKVLIATVKGDVHDIGK
NIVAVVMACNGYEIRDLGVMVEPERIVEEAVAWGAQCICLSGLITPSLDEMARVCEELERRGLRIPVIIGGATTSDLTAVKSGVAVHSANASRNSQILAQ
LL-
>tr|I3YIJ2|I3YIJ2_ALIFI Methionine synthase (B12-dependent) OX=679935 OS=46020 / CIP 107999). GN= PE=3 SV=1
--Q----LES-RILLLDGGFGTMVQQYGFTEG-CNDLLALTRPEAVREIHVKYLQAGADIIETDSFNANAVSLADGLYAYEMSRAAAAVARSAADEPRFV
AGSMGPTNRTASAAREVTFAQLVEAYTDQARGLLDGGADILLVETIFDTLNAKAALYAIDALRTIRVMASGTLASGRTLSGQTVEAFCTSLSHAQLLSLG
LNCAYGAKQLLPYLERLAETAPFRISAHPNAGLPNV--MG--GYDETPEMFAEDVGEYMRRGVNIVGGCCGTTPAHIFELSKIACNYAPRPVPAP-RRVT
T-LSGLEPLRIAPETNFVNVGERTNVAGSAKFARLIREGNYEEALSVARAQVDAGAQIVDVCMDDGMIDGVEAMRTFLNLMASIARVPTMIDSSKWEVLA
AGLEVTQGKAVVNSISLKEAEFLRRAREIHRYGAAAVVMLFDEQGQADTCERKIEVASRAYRLLD-AGFPAEDIIFDPNILAVATGIPEAKAFIDATRWI
KENLYAKVSGGVSNLSFAFAVREAMHSAFLYHAIRAGMDMGIVNPQMVKIYSEIEVEDVILCRRADAAERLTEYAQQVRTT-T-QPQAPD-A--WRLAER
IGHAMLKGVADYIEQDALEGYEALGTPMAVIDTLLMPAMERVGTLFGEGKMFLPQVVKTARVMKRAVAALTPYIEQGGAHNA-GKVLIATVKGDVHDIGK
NIVAVVMACNGYEIKDLGVMVESQRIVEEAVAWGADCICLSGLITPSLDEMAHVCEELERRALRLPVIIGGATTSNLTAVKSGLVIHSPNASRNSQILAQ
LL-
>tr|D9V2P5|D9V2P5_9ACTO Methionine synthase OX=591158 OS=Streptomyces sp. AA4. GN=SSMG_02611 PE=3 SV=1
--NLRNLLDQ-RVVVLDGAWGTMLQGAGLAPG-DPDLLNLTRPDVVLDVHRQYLAAGADITTTNTFTATSIGQADGLRVREMNLRAAELARQAADENRFV
AGSIGPLNVTLSPFRAVTYEEVKASYAEQTKALADGGVDLLLIETIFDTLNCKAAITAAREVPHLPLWISVTIVSGRTLSGQTVEAFWTSIAHARPLIVG
VNCSLGAEEMRPHVEELAKLADTYTACHPNAGLPNA--FG--GYDQTPEETGGMLGEFAGAGVNIVGGCCGTSPAHIAKIAEAVKGLPPRPVPAH-EP-S
TRFSGLEPFKIGADTGFVMIGERTNVTGSAKFRRLIEAGDHQAAVDVALEQVRGGANLLDVNFDADLLESEREMTTFLNLIATVARIPVMIDSSRWSVLE
AGLRCVQGKGVVNSISLKEGPFLEQARRIHDYGAGVVVMAFDEKGQADTVERKVEICSRAYDLLTQAGFAGEDIIFDPNVLAVATGISEAKAFIEALPLI
KERCGAHASGGISNLSFSFVVREAMHSAFLFHAVRAGLDMGIVNAGQLAVYEDIPVEDVLFDRRPDATDRLVEFAETVKGS---TKRVVDLS--WRVAER
LSHALVHGIVDFIEDDTEEARQQFARPLEVIEGPLMDGMKIVGDLFGSGKMFLPQVVKSARVMKRSVAYLEPYMEAEKASRGNGKVVLATVKGDVHDIGK
NIVGVVLGCNNYEVIDLGVMVPAAKILDTAVAEHADVVGLSGLITPSLDEMVSVAQEMQRRGLKLPLLIGGATTSKQTAVKDHTTVHVLDASRVVGVVSD
LL-
>tr|G8SEG0|G8SEG0_ACTS5 5-methyltetrahydrofolate-homocysteine methyltransferase OX=134676 OS=Actinoplanes sp. (strain ATCC 31044 / CBS 674.73 / SE50/110). GN= PE=3 SV=1
--TLRELLAE-RVLVLDGAAGTMLQGARLSPG-DPDLLNLTSPDVILDIHRQYLAAGADIITTNTFTATTIAQADGLLVRDMNVRAARLARQAADEPRFV
AGDVGPLNVTLSPYRAVTFDQVKTAYAEQIAALAEGGVDLLMIETVFDTLNAKAAIAAAREVPDLPLWVSVTIVSGRTLSGQTVEAFWRSIERARPLVVG
LNCALGAAEARPHVAELARLSDTFVAAHPNAGLPNA--FG--GYDQTPAETGALIGEFAASGVNIVGGCCGTTPPHIAEVARAVAGAAPRVVAPP-AP-T
TRFSGLEPFAIGPDTGFVMIGERTNVTGSARFRRLVEADDYQAAVDVALDQVRGGANLLDVNMDADLLDSERAMTTFLNLIATVARIPIMIDSSKWNVLE
AGLKCVQGKAVVNSISLKPDLFLRQARRIRDFGAGVVVMAFDEQGQADTTERKVEICGRAYDLLED-GFDPTDIIFDPNVLAVATGIAEAKAFIDALPLI
KQRCGARTSGGISNLSFAFVVREAMHSAFLFHAVRAGLDMGIVNAGQLAVYQDIPVEDVLFDRRPDATDRLVTFASTVTGS---AKREVDLS--WRVEQR
LSHALVHGIVDFIEADTEEARLKLPRPLDVIEGPLMDGMGVVGDLFGAGKMFLPQVVKSARVMKRSVAYLLPYMEKDKTSRGQGRVVLATVKGDVHDIGK
NIVGVVLGCNNYEVIDLGVMVPAAKILETAIAEGADAIGLSGLITPSLDEMVAVGAEMQRRGMTLPLLIGGATTSKQTAVRDGATVHVLDASRVVGVVSD
LL-
>tr|D2PQB9|D2PQB9_KRIFD Methionine synthase OX=479435 OS=Kribbella flavida (strain DSM 17836 / JCM 10339 / NBRC 14399). GN= PE=3 SV=1
--SLRDLLDR-RIAVLDGAWGTMLQAANLTSG-DPDLLNLMRPDLILDVHRQYLDAGADITTTNTFTATSIGQADGLLVREMNLEGARLARQAADEGRFV
AGSVGPLNVTLSPYRAVSFEQVRDSYAEQITALRDGGVDLLLIETIFDTLNCKAAIAAAREAPELPLWISL-FVSGRTLSGQTVEAWWNSIEHAEPLVVG
VNCSLGARELRPHVADLARFADTYVASHPNAGLPNA--FG--GYDETPEQTAGMIGEFAESGVNIVGGCCGTTPAHIAKIAQAVAGAAPRTVVPP-AG-T
TRFSGLEPFKIGADTGFVMIGERTNVTGSARFRRLIESDDFQAAVDVALDQVRGGANLLDVNMDADLLDSEQAMTTFLNLIATVARIPIMIDSSKWTVLE
AGLKCVQGKGVVNSISLKEQEFLERARRIRDYGAGAVVMAFDEQGQADTVERKVDICGRAYDLLG-IGFPAEDIIFDPNVLAVATGMSEAKNFIDALPLI
KQRCGVHISGGISNLSFSFIVREAMHSAFLYHAGKAGLDMGIVNAGQLAVYEDIPVEDVIFNRRDDATDRLVSFAENVKGK---TQRVVDLS--WRVEQR
LSHALVHGIVDYVEADTEEARQQFARPLEVIEGPLMDGMKIVGDLFGAGKMFLPQVVKSARVMKRSVAYLEPFMEAEKEVRDQGKVVLATVKGDVHDIGK
NIVGVVLGCNNYEVIDLGVMVPAAKILDTAIAEGADVVGLSGLITPSLDEMVTVAAEMQRRGLELPLLIGGATTSKQTAVRDQTTVHVLDASRVVGVVSD
LL-
>tr|H8GYK6|H8GYK6_DEIGI 5-methyltetrahydrofolate--homocysteine methyltransferase OX=745776 OS=I-0). GN= PE=3 SV=1
-------------------------------G-NFDLLQLTRPDVIRQVHRDYFAAGADIASTNTFNSTTISQADGTLAFAMNEAGARLAREVADEPRWV
AGSVGPTNRTATPFRNVTYDDLVEAYTSAVRGLMAGGADLILLETVFDTLNAKAALFACDEARRLPVMLSGTITSGRTLSGQTPEAFAVSTEHAHLFSLG
LNCALGADLLRPHLRAIAANTGALVSVHPNAGLPNA--FG--EYDETPEHTASVLADFAREGVNIVGGCCGTTPEHIRAIADAMSALPPRTAPER-TP-Y
LRLSGLEAFTLTPETNFVNVGERTNVTGSPKFAQAILAGDYDAGLKIARQQVTNGAQVVDINFDEGMLDGEAAMVKFLNLLAGISRVPLMLDSSKWEILE
AGLKRVQGKAIVNSISLKEEKFLERARRLRRYGAAAVVMAFDERGQADNLQRRQEITARAYKLLEQADFPPQDIIFDPNVLTVATGIEEALDFIEATRWI
KANLGALVSGGISNVSFSFHVREAMHAVFLYHAIRAGLDMGIVNAGMLAVYADIEVEDVILARRPDATERLLTLADQYKGI---REAAAQSA--WRVAQR
LTHALVQGITDHVEADAEEAYRELGSPLAVIEGPLMDGMNVVGDLFGAGQMFLPQVVKSARVMKRAVAYLTPYMEAEQQSGGKGKVLLATVKGDVHDIGK
NIVGVVLACNGYQVTDLGVMVPTEKVLDEAQRIGADVIGLSGLITPSLDEMVGVAREMTRRGMTQPLLIGGATTSRATAVKEGTVVHVLDASRAVTTTSD
LL-
>tr|G8QYQ3|G8QYQ3_SPHPG 5-methyltetrahydrofolate--homocysteine methyltransferase OX=158190 OS=Sphaerochaeta pleomorpha (strain ATCC BAA-1885 / DSM 22778 / Grapes). GN= PE=3 SV=1
--QLLKLLSE-RVLVLDGAMGTMIQNQGLRDG-CNELLSLTRGDVIFDIHTQYLQAGSDIITTNTFCANSFNLEEGLEVETLNRAACEIAREAAADYAFI
AGTLGPTNRSLASFRKSDFKGFEEMYLQQAGVLLDGGVDLLLIETVFDTLAAKAAIRSCFKARKVPVMVSVTFSSGRTLSGQTLEAFVSSLAPFPIFSLG
LNCSTGPEQMVPLIEKLSAISPFFVSAHPNAGFPDK--EG--HYTLTPRQLADQMAPVLGKGLNIVGGCCGTTPEHIQALKEATNRAKV-HVKNE-RPPV
L-LSGLERLEVRDGS-FLVIGERTNVAGSKKFARLIKEENWEEALSVARNQIAQGAQVIDICMDASMLDAPKAMVAFLRQVASVSKVPVMIDSSDWEVIE
IALGEIQGKGIVNSISLKEEKFLSHARLIASYGCAMVVMLFDEKGQADHYERKIAIAKRSYDLL-QAGIKPEDIIFDANVLSIATGIDEAKDFIRASLWI
KENLFAHTSGGISNLSFSFVLRNAMHAMFLAFA---KLDMAIINPGADRNLDSIPIGKALLTKAAQARQNLIDLALS--GEQT-KEKTKEEA--WKPEER
LAEAIFHGENTFLQTDLASLDS--MDPIQLVEGPLMYGMKKVGKLFGEGKLFLPQVVRSARTMKLAVDILEPRITAYLTNKI-GIAVMATVKGDVHDIGK
NIVNLILTCNNFEVIDLGVMVPPQKILASALEHKADLVGLSGLITPSLKEMASVVSLFEANGCTIPLFVGGATTSELTAVKSSAVIQTKDASSMALAAQK
VV-
>tr|H1DHD7|H1DHD7_9PORP Methionine synthase OX=742817 OS=Odoribacter laneus YIT 12061. GN=HMPREF9449_01673 PE=3 SV=1
---LKNLLEE-RILILDGAMGTAIQQYQLEEG-NNDILSLTRPDIISRIHQSYIDAGADIIETNTFNSNAVSQADQCDVYRLNYAGARLAREVADKPVYV
AGSIGPTSKTLSPFRAIDFDTLAATYAQQISGLIDGGVDILLVETVFDGLNAKAALYAIDKITRLPVMISATINSGRTLTGQSLEALYTALAHYPLFSFG
LNCSFGAKELLPFVEQLHKFLPCNLSLYPNAGLPNE--MG--EYDESPDYTAAFLKSMAQKGLNIAGGCCGTTPAHIRAIRKALEGIAPR-IPA--KPFL
V-VSGLDNIVVKALSNFVNVGERTNVAGSAKFAKLIHADAYDEASNIARKQIEDGASIIDINMDDAMLDSAKEMATFIRIISNIAKAALMIDSSDWKTLL
AGLKNAQGKCIVNSISLKEKEFLRKAAEIKRLGAAVVVMAFDEEGQAVSYERKIAICQRAFQLLEQAGFAPENIIFDVNILAIGTGMEEAVDFIRAVAWT
KKHLGSSTSGGVSNLSFSFPVREAMHSVFLYHAIAAGLDMAIVNPSLLQVYDDIDVEAVVLNKNPEATEHLIELAEKMKAHEE-KTIKNE-S--WRLEER
LIYALVKGIKEYLPEDISAALQAYASPVEIIEGPLMKGMDKVGQLFGEGKMFLPQVVKSARIMKEAVAILQPAIEHSNSSDIKHKVVLATAKGDVHDIGK
NIVHIVLSCNNMEVIDLGVMVDNHRILEAARQYQADIIGVSGLITPSLAEMEDLCRLLEQAQLKIPLLVGGATTSSVTAVKSYGVLHGGDASRTAGLIKR
LL-
>tr|F9ZAP2|F9ZAP2_ODOSD Methionine synthase OX=709991 OS=NCTC 10825 / 1651/6) (Bacteroides splanchnicus). GN= PE=3 SV=1
---IQDEIKK-RILILDGAMGTAIQQYGLTEG-NNDILNLTCPEVIRQIHRSYIEAGADIIETNTFNSNAISQAERGLVYRLNYAGAKLAVTEARAQVYV
AGSMGPTSKTLSPFRPVDFDTLVSTYAEQVSGLIDGGVDLLLVETVFDGLNAKAALYAITQVTSLPVMLSATINSGRTLTGQSLEALYTTVSHYPLFSFG
LNCSFGATDLLPFIERLSKTLPCPLSIYPNAGLPNE--MG--EYDESPELTASCLKQMATAGLNIAGGCCGTTPEHIRAIREALQAISPRQIPA--IPAL
V-VSGLDKVVVKAQNNFINVGERTNVAGSAKFAKLIHAKAYEEAARIARKQIEDGASVIDINMDDAMLDSALEMSTFVRYISNIARAALMIDSSDWNTIL
AGLKNAQGKCIVNSISLKEDLFLAKAREIHHLGAAVVVMAFDEQGQAVTYERKIEICERAYRLLRQAGFRAEDIIFDVNILAIGTGLEEAVDFIRAIAWI
KANLGCRTSGGISNLSFSFPVREAMHSVFLYHAIEAGMDMGIVNPAMLQVYDEIEVEEVVLNKHPEATERLIELAEQIKGQADGKAIKNE-E--WRLSER
LNFALIKGNTEYLEADLAEALTVYASPVEIIEGPLMQGMDKVGTLFGEGKMFLPQVVKSAKAMKAAVAILQPEIEKHNAENIRPKVVLATAKGDVHDIGK
NIVSIVLTCNNFDVIDLGVMVDNQKIVAAAKAHQADLIGVSGLITPSLSEMEALCELLQKEQLRIPLIVGGATTSTVTAVKDYGVIQGGDASRTAGIMKR
LL-
>tr|J0LM35|J0LM35_9BACT Methionine synthase OX=1144253 OS=Pontibacter sp. BAB1700. GN=O71_08967 PE=3 SV=1
--PIHTLLQE-RVLVLDGAMGTMIQRYQLSEG-NNDLLSITRPDIIKAIHTEYLEAGADIIETNTFSGTTIAMADKLIVYELNYESARIAREAADEKRFV
AGAIGPTNRTASPFRAITFDQLVEAYYEQVRGLVDGGADLLLVETVFDTLNCKAALFAIQQHKELPIMVSGTITSGRTLSGQTVEAFWNSISHAPILSVG
FNCALGARQLKTHIQELSRISNCYISAYPNAGLPNA--FG--GYDETAQQMGAIVEEYLKEGVNVLGGCCGTTPVHTKVIADLVRRYKPHTPTPV-AP-L
PRYSGLEPLTITSDTLFVNVGERTNVTGSKKFSRLIVDGKFEEALSVARQQVEGGAQIIDVNMDEGMLDSEQAMTDFLHLIASIAKLPIMIDSSKWSVIE
AGLKCVQGKSIVNSISLKEEAFKKLARKVRQYGAAVVVMAFDEQGQADTLPRRIEICERSYRILDEVGFPPQDIIFDPNILAIATGIEEAVDYIEAVKWV
KANLHAQVSGGVSNLSFSFLVREAMHTIFLYHAVQAGMDMGIVNAGMLGIYEEVPIEDVIFNQHPDATEKLVNYAETIKGKG--KTTAADNA--WRVEER
LKHALVKGIVDYIEEDTEEARQKATKTLDVIEGPLMAGMQVVGDLFGAGKMFLPQVVKSARVMKKSVAYLLPFMEAEKASSAQGKILMATVKGDVHDIGK
NIVGVVLACNNYEVIDLGVMVQLDKILAEAEAQQVDVLGLSGLITPSLDEMVYVAQEMERRGMKIPLLIGGATTSRVTAVKSGPVVHVHDASRSVTVVSN
LL-
>tr|A5TSW8|A5TSW8_FUSNP Methionine synthase OX=393480 OS=Fusobacterium nucleatum subsp. polymorphum ATCC 10953. GN= PE=3 SV=1
--E----LKE-RILVLDGAMGTVLQKYELTPG-CYEILNETRPDIIFEVHKKYIEAGADIIETNSFNCNAISLKDHLKVYDLAKKSAEIARDAVKEKVYV
FGSIGPTNKSLSPKRAVSFDEMKEVIKVQVAGLIDGGVDGILLETIFDGLTAKAALLATEEVVKLPISISAT-VQGKLLTGQSMESLIAALDRDSVTSFG
FNCSFGAKDLVPLVIKIKELTTKFVSLHANAGLPNQ--NG--DYVETAQKMRDDLLPLIENQINILGGCCGTSYDHIRAIAEMVKGQKPRVLPK--EN-L
LTLSGNEIYNFNDK--FTWVGERNNISGSKLFRTMIEEHNYLKALEVARQQIDAGAKVLDINVDDGILDSVEEMKNFLRVLQNIAKVPIMIDSSDFAVIE
EGLKNTSGKAIVNSISLKTEEFLRKAKIIRKYGASIVVMAFDEKGQGVSAERKIEICQRAYDLLS-IGVKNSDIVFDPNILSVGTGQEAAREFIKTIDYI
HENLGCGVVGGLSNLSFAFVLRAAFHHIFLEEAVPRGFNFAILNPKEKAP--QWTIKSFIFGDSTD-MEALLSLNL-VK-----KKEDAQ-I--FA-EDK
IRKALIQGGSESLQEVIGDLLKKY-KALEILENILMSAMQEIGRLFEQGELYLPQLIRSASVMNNCVDILTPYLEKVDKTSSKGKILMATVDGDVHDIGK
NIVGTVLECNGYEVIDLGVMVPREKIVETAKEINADVVTLSGLISPSLKEMERVADLFQKVGMQVPVLIAGAATSKLTGLKDYS-LHVTDAMDTITVVSQ
LL-
>tr|C3DQ64|C3DQ64_BACTS Methionine synthase OX=527026 OS=Bacillus thuringiensis serovar sotto str. T04001. GN= PE=3 SV=1
---IEEKLQN-SILILDGAMGTMIQQEDLTAEDFGGELVETRPDVILKIHKAYIEAGADIIETNTFGATNIVLSDELSLDELNEKAALLAKQAVKEEVYV
AGAMGPTTKAISVTGGVTFEELIEAYTRQARGLLKGEVDVLLVETSQDMRNVKAAYIGIQAKKTVPIMISGTIEMGTTLAGQTIEAFYLSVEHMKPLSVG
LNCATGPEFMRDHIRSLSDLSECYISCYPNAGLPD--EDGH--YHESPSSLAEKVKRFAEEGVNIIGGCCGTTPEHIKAMKSALASLKPRDHHE--REGH
GISGLEALQYDE-SMRPLFVGERTNVIGSRKFKRLVAEGKFEEAAEVARAQVKKNAHIIDICMADPDRDEIEDMEKFLTEVTKVLKVPIMIDSTDENVMA
RALTYIQGKAVINSINDGEERFEKVTPLLRKYGAAIVVGTIDEDGMAVSAERKLEIAKRSYELTTKYGIRPSDIIFDALVFPVGTGDEEAAATIEGIRLI
KEALECLTILGVSNISFGLPGREVLNSVFLYHATKAGLDYAIVNTEK------LERYASIPEEEKHLADTLEEFTNFYAKK----KDVVVQET-LTLNER
LANYIVEGTKQGLHEDLSLALEEGRKPLDIINGPLMTGMDEVGRLFNNNELIVAEVLQSAESMKAAVSYLEPYMESS-DSDEKGK---------------
----------------------------------------------------------------------------------------------------
---
>tr|G5H874|G5H874_9BACT Putative uncharacterized protein OX=742725 OS=Alistipes indistinctus YIT 12060. GN=HMPREF9450_01134 PE=3 SV=1
---LLSELSR-RILVLDGGLGTMVQAYGLGEG-CNETLALTRPDVLTEIHEAYLQAGADIISTDSFNANALSLSDMLYVYDICRAAASLARAAADRSRFV
AGSVGPGNRSASPDVAVTFDELKQAYYDQVRGLVDGGADLILIETFFDTLNAKAAIFAVGELTRIPVMVSGTTDSGRTLSGQTVEAFYTSVHHGDVISVG
LNCGLGAEKMRPYIERLAAVAACAVSAHPNAGLPDK--EG--HYDETPEMMAETVEQYLSAGLNIVGGCCGTTPVHIAAIAAVAARTTPRTIPE--PDGN
LLLSGLEPLRIG--PEPLTVGLQADATVSPEFAVAIRDKRYETAANAMRAAIETGSPLAAVCVDDAMGAGPAAIRDLLNIAMATARVPVAILSSDWKTLE
AGMQCVQGKPLIGPLSLADEEFVRRVSLAARYGAAVLVALADEEGDARSYRRKTSVAARVAGLLERTGFPSCDVAVDPGVCPVGIGEEDPSDFFDACRGI
RQQYQWKLCGRIGVVSDRYRVCRALNGVWLSRAAEAGLDLAFADEDALRLLGLC--EKAIAGS--------------NPE-----A--------------
------------------I-----KETAT---------LAGLGELYRAGTIPFALLERGISVVT-----------------GWGRVLMATVGDDGYDPGR
AALKTLLLVSGCRVEDMGLVREPRRIIE----NRFDAVLLRGVSARGVGQIAFLLAVAQKQGLQIPFLVGGPAASPQYGA--GAVLYGGEPVATWRALRR
IA-
>tr|F0RX30|F0RX30_SPHGB Methionine synthase OX=158189 OS=(Spirochaeta sp. (strain Buddy)). GN= PE=3 SV=1
MNRLKSLLSQ-RIVLLDGAMGTMIQSQGLAIG-CNEVLNLTRGEILFSIHQQYLEAGSDIIETNTFCANAFNLAEGLHVQTINQAACEIAREAAADGAFV
AGVLGPTNRSLSPKVQSDFADFHAMYLEQARVLVQAGVDLILIETVFDTLAAKSAILACQDARSLPIMVSVTSDSQRTLSGQTLQAFVTSLSSFDLFSLG
LNCSTGPDEMLPLIEQLDALCPFFVSAHPNAGFPDK--EG--AYALSAEGMAAQLARAIKEQLNILGGCCGTTPAHIAALKAATSQAKGRIKPQ--ENQN
LKLSGLDDISIE--HSLLVIGERTNVAGSRKFARLIKEGKWEEALAIAREQVKEGAQVLDICMDASMLDAKISMRSFLRHIAGVSKAAIMIDSSDWSVIE
AALGEVQGRGIVNSISLKEQIFIQHAKQVSSYGHAMVVMLFDEEGQAATFERKMAIAKRSFELLTASGIKEQDIIFDANVLSIATGIEEARDFILATRAL
KKLYLCHTSGGVSNLSFSFRIRTAMHAVFL---SLAELDMAIINPSSLITRTII--QKALLAEDGDLANLIALALEMQED-----EPQLQK---ASASQR
LFDAILAGDHAYLEPDLKELEGE--NPLTLVEGTLMDGMKEVGRLFGLGKLFLPQVVRSARTMKLAVDILQPYLELNTNSQKKPVAVMATVKGDVHDIGK
NIVNLILRCNGFEVIDLGVMVPPEAIWEAAIRHKADLVGLSGLITPSLKEMETVIKLFEKKGSSLPIFVGGATTSVLYS---EAVIQTKDASAMALAAKQ
VV-
>tr|B9XS35|B9XS35_9BACT Methionine synthase OX=320771 OS=Pedosphaera parvula Ellin514. GN=Cflav_PD0446 PE=3 SV=1
-------------------------------------------------------------------SQAISLADKMLAYELSKAGAACARRAAEEGCFV
AGAMGPTTRTSSTDVGTTYDELVQAYYDQAKGLIDGGADILLVETIFDTLNSKAAFFAIERLYRLPIMASVTQASNRGVTGQTVEAFWNSISHVPLVSVG
MNCALGPKEMRALIEELSNIAPIYMSAYPNAGLPNP--LT--GFPETPESLAPQLKEWASNGLNVVGGCCGTTPPHIKMIAEAVRGLKPRVVPT--VEPY
LRLSGLEALTVE--TNFVNVGERTNVTGSPKFSKLILEGKYEEALSVAKQQVVNGAQVIDVNMDEGMLDGAKAMTHFLNLIASIARVPIMVDSSKWSVIE
AGLKCIQGKGVVNSISLKEEKFKEHAKLVRRYGAAVVVMAFDEKGQADNFARKIEVCKRSYDILTKEGFPPQDIIFDPNILTVATGMDEAVDFIEATRWI
KQNLHAKVSGGISNISFSFRVREAMHSAFLYHAIKAGLDMGIVNAGMLELLELV--EDVLLNRKPDAERLIKFAESVKQK-----GTEVVA---DTVEER
LSHALVKGIVDFIDQDTEEARQKYGKPLLIIEGPLMSGMNVVGDLFGSGKMFLPQVVKSARVMKKAVAYLLPYMEEEKKTRANGKILMATVKGDVHDIGK
NIVGVVLGCNSYEVIDLGVMVSSEKILAAAKEHNVDVIGLSGLITPSLDEMAHVAKEMKRQGFTLPLLIGGATTSPGYN---EAVVHVLDASRAVGVVGQ
LL-
>tr|E3HDK0|E3HDK0_ILYPC Methionine synthase (B12-dependent) OX=572544 OS=Ilyobacter polytropus (strain DSM 2926 / CuHBu1). GN= PE=3 SV=1
---MRELLKE-KILILDGAMGTAIQNYSLEEG-CNELLNLTKPEVLEEIHLSYLEAGADIIETNTFNSNRISMREGLKSYDLSKAGAELAVKAARKRIFV
AGSMGPTSKSASPTGEVSYSELKAAYKEQALGLFDGGVDAFLIETIFDGLNAKAAVIAIEEVEKLPIMISGTVDNGKLLSGQSIESLIVAIDRDSIISYG
LNCSFGAKELIPLIKKLGKLTKKNISLYPNAGLPNE--KG--EYDETPHMTGSYVKELIENKINILGGCCGTTPEHIKVMAELAQGKSPRKTSM--ENLA
GIVSGNDTVSLH--EEFLVVGERNNVSGSRKFARLIREESYDEALDIARTQVEKGAKILDINLDDALLDSVEEMEKFIRLLQNLSKLPIMIDSSNFDVIE
KGLENLAGKGIVNSISLKEHEFLRKAAVVRKFGAALVVMAFDEKGQAVSSERKKEICKRAYELLTSNNFPAEDIIFDPNVLTVGTGTEEGVDFIDSVKWI
KENLGAGVSGGVSNLSFAFRLRHTIHKIFLEEGEKAGMTMAIVNPGEDPVRKAV--ENLLAGDKNAVDEILNLSFEKSKK-----TAEIKP---VTVEER
LKDYLLKGRSQGIEDDIKTALEKY-SPLQVIQEVLMEGMEEVGALFEKGELFLPQILRSAAVMEKAVEFLTPLIEAGGKEKVKGKVLMATVEGDVHDIGK
NIVGTVLKCNGFDVVDLGVMVPKDQILEAILRHDVDMVTLSGLITPSLMEMEKVAEMMAEQNMDIPLLIGGAAASPKYS---GRVIHVTDASGTLPVVSS
LM-
>tr|K8HTJ0|K8HTJ0_LEPBO Methionine synthase OX=1049782 OS=Leptospira borgpetersenii str. UI 09149. GN= PE=4 SV=1
-------------------------------------------------------------------------------MDLNKAAVQCARNAIEKHCFL
AGTIGPTTRTATPDVAVTFDDLVATFYEQARALVEAGVDLLLPETNIDTLNLKAAIFAIEQVVRIPVCLSVTTDSGRTLSGQTVEAFYNSIAHCNPLSVG
INCALGADEMRPYIEELARISSCYISCYPNAGLPNA--FG--GYDQTPEEFGAYIQEFASSGLNIAGGCCGTTPEHIAAATKVVQGKKPRVLPQ--IEEI
TRLSGLEPLNVD--KGFLLVGERTNVTGSPKFKKLIIEGNFEEAVSVALQQVEAGANIIDINFDEALLDGEASMRHFLNLIAGIAKVPFMIDSSKWSVLE
EGLKCIQGKPIVNSISLKEEKFLEHARKIQRYGASAIVMAFDEQGQAATKDEKVRICKRAYDLLVTKNFSPTDIIFDPNILTVATGIEEAVDFIEAVREI
KKFCGAKVSGGLSNVSFSFRVREAMHSVFLYHAIQAGLDMAIVNAGMLALLEYV--EDVILNRRPDAERLVEFAESIKSS-----GSEKKG---ETVEER
LSYALVKGIVEYIDQDTEEARLKYGRPLTVIEGPLMDGMKIVGELFGAGKMFLPQVVKSARVMKKSVAYLLPFMEEEKNVAARPKFLIATVKGDVHDIGK
NIVGVVLACNNYEVIDLGVMVPSDKILEEARKHNVNIIGLSGLITPSLDEMVHVASEMKRTGFEIPLLIGGATTSPVYN---PPVVHVVDASRVVNVVNQ
LL-
>tr|C6JIG3|C6JIG3_FUSVA Methionine synthase OX=469618 OS=Fusobacterium varium ATCC 27725. GN=FVAG_02060 PE=3 SV=1
---MINELKK-RILVLDGATGTAIQKYNLSEG-CNEILNISRPDIIKEIHTGYIKAGADIIETNSFNCNRISLKDGIMSYTLSKKGAELAREIADNKIYV
AGSIGPTSKSLSPVGELNFDQMKNIYSEQIEGVIDGGADCILIETIFDGLNAKAALIAAEELIQLPIMISATVNQGKIFSGQSIESLIVALDRPSIISFG
LNCSFGAKDLIPMIKKIAAFTDKYISLYPNAGLPNE--NG--EYEETPEITTGYLKELVDKKVNILGGCCGTHFSHIKAIADLVKNKEPRPIVK--EN-K
CFLSGNEIYNFN--NKFTVIGERNNVAGSKIFKTLIEEKNYIKALEIARLQIEKGAAVLDINLDDGLLIPHEEMEKFLRIIQNVSKVPIMIDSSDFLTIE
TALKNIAGKSIVNSISLKEESFRKKARIIKKYGAAVVVMAFDEKGQGISFERKIEICNRSYKLLKEENFSDSDIIFDPNILAIGTGSKDGLNFLKTIQWL
KENLYCGISGGLSNLSFAFRLRAAIHSLFIEAAKEKGMNFAIMNPGEKAERDII--LALINGNTESLDSILELAAKLKNA-----SVNLKP---NSLKDR
IERALIYGGSTTFDTDINTALKNM-TPLDIIQNILMKGMDKIGILFEKGELYLPQLIRSASVMNKAVDILKPHMKVKADIRIKGKILMATVEGDVHDIGK
NIAGTVLKCNGYEVIDLGVMVSKEKILEEAIKNSVDIITLSGLISPSLKEMEKTLSLLNENKISIPVLVAGAATSPFYK---KRTFHTTDALDTLTMINK
LI-
>tr|F7MI06|F7MI06_9FUSO Putative uncharacterized protein OX=469601 OS=Fusobacterium sp. 21_1A. GN=HMPREF0404_01732 PE=3 SV=1
MFEIEKDLKE-RILVLDGAMGTVLQKYELSAG-CYEILNETRPDIIFEVHKKYIEAGADIIETNSFNCNAISLKDHLKVYDLAKKSAEIARDAV--KVYI
FGSVGPTNKSLSPVGAVSFDEMKEVIKVQVAGLIDGGVDGILLETIFDGLTAKAALLATEEVVKLPISISTTVNQGKLLTGQSIESLIVALDRDSVTSFG
FNCSFGAKDLVPLVIKIKELTTKFVTLHANAGLPNQ--NG--DYVETAQKMKNDLLPLIENQINILGGCCGTSYDHIKAIAELVKGEKPRVLPE--KNLE
TCLSGNEIYNFK--DKFTCVGERNNISGSKLFRTMIEEHNYLKALDVARQQIDAGAKVLDINVDDAILDSVEEMKNFLRVLQNIAKVPIMIDSSDFAVIE
EGLKNTAGKAIVNSISLKEENFLRKAKIIRKYGASIIVMAFDENGQGVSAERKIEICQRAYNLLKSIGIKNSDIVFDPNILSVGTGQEAAREFLKTIDYI
HKNLGCGIVGGLSNLSFAFRLRAAFHHIFLEEAIPRGFNFAILNPKEKAEREKI--KSFIFGDSTNIEDLLSLNLVKRKE-----NTQIFA---ETPEDR
IRKALIQGGSESLQEVIEELLKKY-KALEILENILMSAMQEIGRLFEQGELYLPQLIRSASVMNNCVNILTPYLEKVDRTSSKGKILMATVDGDVHDIGK
NIVKTVLECNGYEVIDLGVMVPREKIVEVAKKNNVDIVTLSGLISPSLKEMERVADSFQKVGMQIPILIAGAATSPNYD----YSLHVTDAMDTITVVSQ
LL-
>tr|C3WBE7|C3WBE7_FUSMR Methionine synthase OX=469616 OS=Fusobacterium mortiferum ATCC 9817. GN=FMAG_00746 PE=3 SV=1
-MDIKKELQK-RILVLDGAMGTAIQKYNLNSG-CNEILNITRPDIIKDIHLKYIEAGADIIETNSFNCNKISLNEGFRAYEIAKRSAELAKEVT--KIYI
AGSIGPTNKTLTPSGDLEFDYLKEAYSEQIEGLIDGGVDILLIETIFDGLNAKCAVISAEEVINLPIMISATVNEGKIFTGQSIESLIVALDRESIISYG
FNCSFGAKELIPLTKKLGKFTKKPISLYPNAGLPNE--DG--EYLESPDITANYLKELVDNQVNILGGCCGTTFEHIKSIANLVKNRAPRKF-E--ENLE
GFLSGNEILYFN--DKFVDVGEKNNVAGSKIFKNLIADKNYIKALEIAKKQIENGAKVIDINMDDGLFESKIEMKNFLIVIQNVSKIPIMIDSSDFEVIE
TGLKNIAGKSIVNSISLKEEEFRKKAQVIKKYGASVVVMAFDEKGQGVSYERKIEICSRAYSILKEIGYSNSDIIFDLNILTIGTGMESGLNFLKACEWI
RKNFGVGIIGGLSNLSFAFRLRAGLHSIFLEEGKNRGLNFAILNPNENPDKKIL--RDLIFGEESSLEQILNLHIQRKKE-----VV--------TLEQC
IENALIFGETPEFINDINSALKIY-SPLDIIQNILMEGMKKLGVLFEKGEVYLPQLIRSSETMNKAVNIITPHLKSDEKVKAKGKILMATVEGDVHDIGK
NIVGTVLKCNGYEIIDLGVMVPKETILSTAKEQNVDIITLSGLITPSLKEMEKVLKYFQENSMKTLILIAGATTSPLYS---GKVLHVSEALDTLQSINK
LC-
>tr|A3WRU5|A3WRU5_9BRAD 5-methyltetrahydrofolate--homocysteine methyltransferase OX=314253 OS=Nitrobacter sp. Nb-311A. GN=NB311A_03264 PE=3 SV=1
---FRALARE-RILVLDGAMGTMIQDRGFDEGENNDLLILTQPQAIEDIHTQYLRAGADLVATNTFSSTSIAQADDMLVYDLNREGARLARSAAEKPRFV
VGAIGPTNRTISPYRAVTFDDLRKAYGEQINGLLDGGADLLLVETIFDTLNAKAALYAIAEIGDIPVMISGTITSGRLLSGQLPEAFWHSVRHAGPITIG
FNCALGAEDLRAHVAEIGRVADTLVCAYPNAGLPNE--FG--QYDESPDYMARLIGEFAQTGVNVVGGCCGTTPDHIAAIAAAVAPHKPRVVPV--IAPR
LRLSGLEPFSLTSDIPFVNVGERTNVTGSARFRNLIKAGDYAAALDVARNQVENGAQIIDVNMDEGLLDSEAAMVTFLNLIAAIARVPVMVDSSKFSVIE
AGLKCLQGKPVVNSISLKEEKFLHEARIARRHGAAVVVMAFDETGQADTCQRKMEICKRAYDILEQVGFPPEDIIFDPNVFAIATGLEEGVDFIEATRWI
RQNLHAHISGGVSNLSFSFPVREAMHSVFLYHAIKAGMDMGIVNAGQMVIYDDIDPEDVVLNRDPDAGERLEKFRGQG-QA----KEADLSRE-WPVEKR
LSHALVNGITEYIEQDTEEARQSADRPLSVIEGPLMAGMNVVGDLFGDGKMFLPQVVKSARVMKQAVAYLMPFMEEEKNSTSAGKILLATVKGDVHDIGK
NIVGIVLQCNNYEVIDLGVMVPAAKIIETAKAEKADIVGLSGLITPSLDEMGYFAAELERQGLNLPLLIGGATTSPNYR--NGPVIHVNDASRAVGVVAS
LMS
>tr|Q6N3J1|Q6N3J1_RHOPA Methionine synthase OX=258594 OS=Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009). GN= PE=3 SV=1
---LLALAAQ-RILVLDGAMGTMIQQLQLDEGENNDLLILTQPQAIEDIHAQYLRAGADIVATNTFSSTSIAQADEMLAYEMSRDGARLARNAAAKPRFV
AGAIGPTNRTISPYRAVTFDDLRIAYSEQINGLLDGGADILLLETIFDTLNAKAALYAIAEITDVPVMISGTITSGRLLSGQMPEAFWNSVRHARPITIG
FNCALGAKDLRAHIADISRVADTLVCAYPNAGLPNE--FG--QYDESPEYMASLVGEFAEAGVNIVGGCCGTTPAHIKAIAEAVAPHKPRVIPT--IDPR
LRLSGLEPFELTKDIPFVNVGERTNVTGSAKFRKLITAGDYAAALQVARDQVENGAQIIDVNMDEGLLDSEAAMITFLNLVAAIAKVPVMVDSSKFNVIE
AGLKCLQGKPVVNSISLKEDKFLHEARIARRHGAAVVVMAFDETGQADTYARKTEICARAYDILNRVGFPPEDIIFDPNIFAIATGLEEGVDFIEATRWI
RQNLHAHISGGVSNLSFSFPVREAMHSVFLYHAIKAGMDMGIVNAGQMIVYDDIDPEDVILNRDPGASERLDKYRGQG-QQ----KEQDLARS-WPVEQR
LSHALVHGITEFIELDTEEARAKAERPLHVIEGPLMAGMNVVGDLFGDGKMFLPQVVKSARVMKQAVAYLMPFMEEEKNRATAGKIVLATVKGDVHDIGK
NIVGIVLQCNNFEVIDLGVMVPAAKIIETAKAENADIVGLSGLITPSLDEMSFLAGELQRSGFNIPLLIGGATTSPAYP--SGSVVHVNDASRAVGVASS
LLS
>tr|I3BYT6|I3BYT6_9GAMM Methionine synthase (B12-dependent) OX=870187 OS=Thiothrix nivea DSM 5205. GN=Thini_4030 PE=3 SV=1
---LQQAISQ-RILILDGAMGTMIQRYKLQEGENNDLLVLTQPQIIREIHGQYLAAGADILETNTFNATRISMHDDMLAYEINVAAAKLARSVADEPRFV
AGVLGPTSRTISPFRNVTFDELVMNYMESTRGLIEGGADIILIETIFDTLNAKAAVFAVKQVFELPIMISGTITSGRTLSGQTTEAFYNSLSHADALSFG
LNCALGPDLLRQYVEEMSRVSATFVSAHPNAGLPNE--MG--EYDMGPDEVAGHIKEWAQSGLNIVGGCCGTTPPHIAAIAKAVDGIAPRQIPD--LPRE
MRLSGLEPFNIGKDSLFVNVGERTNVTGSAKFKRLIKDGQYTEALQVALDQVENGAQVIDVNMDEGLLDAEKEMHRFLNLVASIARVPVMVDSSKWEVIE
AGLKCIQGKGIVNSISMKEEKFIQQARLVRRYGAAVIVMAFDEKGQADTEARKIEICARAYKILEQVGFPPEDIIFDPNIFAVATGIDEAVDFIEATRWI
KQNLYTSISGGVSNVSFSFPVREAIHSVFLYHAIKAGMNMGIVNAAQMAVYDDIPAEDVIQNKDAGATERLPNYKGDGVET----KKEDLERS-WPVEKR
LEHALVKGIDAYVDEDTEEARVKLGRPLLVIEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKKAVAYLDPFMAAEK-GQANGKILMATVKGDVHDIGK
NIVGVVLQCNSYEVIDLGVMVSAEKILQVARDEKVDIIGLSGLITPSLDEMVHVAKEMQRQDFHVPLLIGGATTSPQY---KNDVVYVQDASRAVGVASA
LLS
>tr|H0TUM3|H0TUM3_9BRAD B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase OX=551947 OS=Bradyrhizobium sp. STM 3843. GN= PE=3 SV=1
---FLAAARQ-RILILDGAMGTMIQALQFDEGDNNDLLILTQPQAIEDIHAQYLRAGADIVATNTFSATSIAQADDLIIYELNREGAKLARNAAQRPRFV
AGAMGPTNRTISPYRAVTFDDLRLAYGEQARGLLDGGADILLVETIFDTLNAKAALYAIAELCDVPVMVSGTITSGRLLSGQMPEAFWNSVRHAKPVTIG
FNCALGAEDLRAHIADIGRVADTLVCAYPNAGLPNE--FG--QYDETPDYMARLIGEFARDGVNIVGGCCGTTPDHIAAIAAAVAPHKPRAVPE--IAPR
LRLSGLEPFELTPAIPFVNVGERTNVTGSAKFRKLITAGDYTAALQVARDQVNNGAQVIDVNMDEGLLDSEAAMRTFLNLVAAIARVPVMVDSSKFHVIE
AGLKCVQGKPVVNSISLKEEKFLQEARIARRHGAAVVVMAFDETGQADTYARKTEICARAYKILEQVGIPPEDIIFDPNIFAIATGLEEGVDFIEATRWI
RQNLGAHVSGGVSNLSFSFPVREAMHSVFLYHAIKAGMDMGIVNAGQMIVYDDIDPEDVVLNRDAGAAERLEKFRGQG-QT----KEADLARE-WPVAKR
LSHALVHGITEFIEQDTEEARAASTRPLDVIEGPLMAGMNVVGDLFGDGKMFLPQVVKSARVMKQAVAYLMPFMEAEKNRSTAGKIVLATVKGDVHDIGK
NIVGIVLQCNNFEVIDLGVMVPATKIIETAKTEKADIIGLSGLITPSLDEMAYLASEMERQDLNMPLLIGGATTSPNYR--NGPVVHVNDASRAVGVASS
LLS
>tr|K8NKD9|K8NKD9_AFIFE Methionine synthase OX=883080 OS=Afipia felis ATCC 53690. GN=HMPREF9697_03290 PE=4 SV=1
---FRALARE-RILVLDGAMGTMIQRLELDEGENNDLLILTQPQAIEDIHYEYLKAGADIVETNTFSSTSIAQADDMLAYELNHEGARLARNAANRPRFV
AGALGPTNRTISPYRAVTFDDLRIAYSEQINGLLDGGADLLLVETIFDTLNAKAALYAIAEICDVPIMISGTITSGRLLSGQMPEAFWYSVQHANPITIG
FNCALGAEDLRAHIADIGRVADTLICAYPNAGLPNE--FG--QYDETPEYMARLVGEFAEAGVNVVGGCCGTTPDHIGAIARAVAPHKPRVVPA--IEPR
LRLSGLEPFVLTNDIPFVNVGERTNVTGSARFRKLIKEGNYTAALQVARDQVENGAQVIDVNMDEGLLDSKQAMIEFLNLVASIAKVPVMVDSSKFEVIE
AGLKCVQGKPIVNSISMKEEKFLHEALIARRHGAAVVVMAFDETGQADTYERKIEICKRAYDLLTKLDFPPQDIIFDPNIFAIATGLEEGVDFIEATRWI
RQNLHAHISGGVSNLSFSFPVREAMHSVFLYYAIKAGMDMGIVNAGQMVIYDDIDPEDVILNRDPGASERLEKFRGQG-QV----KEQDLSRE-WPVEKR
LAHALVNGITEYIEIDTEEARQTVDRPLSVIEGPLMDGMNVVGDLFGSGKMFLPQVVKSARVMKQAVAYLMPFMEEEKNRSSAGKIVMATVKGDVHDIGK
NIVGIVLQCNNFEVIDLGVMVPANKILETAKNEGADIIGLSGLITPSLDEMVFVASEMERQGFDIPLLIGGATTSPRYR--KGPVVHVNDASRAVGVASS
LLS
>tr|E4QN59|E4QN59_METS6 Methionine synthase OX=887061 OS=Methylovorus sp. (strain MP688). GN= PE=3 SV=1
---LRELLAE-RILILDGAMGTMIQRYKLTEGGNNELLTLTQPHIIQEIHEQYLAAGADIIETNTFGATTVAQEDHMLAFEMNVEAAKLARAACDKPRFV
AGALGPTPKTISPARNITFDQLVKAYLEQTIALVEGGADILLVETIFDTLNCKAALFAIDAYFRLPIMISGTVTSGRILSGQTVPAFWHSVRHARPLTIG
LNCALGAALMRPYAEELSKIADTFVCIYPNAGLPNP--MS--DFDEEPQDTSSLLKEFAESGVNVAGGCCGTTPAHIQAIAETVKNIAPRQVPA--PRHA
TLLAGLEPFIIDDSSLFVNVGERTNVTGSKAFARMILNEQYEDALQVARQQVENGAQVIDINMDEGMLDAVKAMTHFLNLVASIARVPIMIDSSKWEVIE
AGLKCVQGKSIVNSISMKEAEFLRQARLCRRYGAAVIVMAFDEKGQADTYERKIEICKRAYDLLKEASFPPEDIIFDPNIFAVATGIEEAVDFINATRWI
KENLYAKISGGVSNVSFSFSAREAIHTVFLYHAIKAGMTMGIVNAGMVGVYDDLPAEDVVLNRREDATERMATLTAGG-KK----EAPTLERG-TPVGKR
LEHAMVHGITEFIVEDTEEARQQVMRPINVIEGPLMDGMNVVGDLFGQGKMFLPQVVKSARVMKQAVAHLIPFIEEEKAGKPKGKVVIATVKGDVHDIGK
NIVSVVLQCNNFEVVNMGVMVPCSEILATAKVENADIIGLSGLITPSLEEMAYVAKEMQRDPHFIPLLIGGATTSPNY---DGPVIYVPDASRSVSVMQS
LLT
>tr|H5YE59|H5YE59_9BRAD 5-methyltetrahydrofolate--homocysteine methyltransferase OX=319017 OS=Bradyrhizobium sp. WSM471. GN=Bra471DRAFT_01202 PE=3 SV=1
---LLDAARE-RILVLDGAMGTMIQNLQFDEGENNDLLILTQPQAIEDIHAAYLRAGADIVATNTFSTTSIAQADDLIVYEMAREGARLAGNAARRPRFV
AGAIGPTNRTISPYRAVTFDDLRKSYGEQINGMLDGGVDLLLVETIFDTLNAKAALYAIAEITDMPVMVSGTITSGRLLSGQLPEAFWHSVQHARPVTIG
FNCALGAKDLRAHIADIGRVADTLVCAYPNAGLPNE--FG--QYDETPEYMARLVGEFARDGVNIVGGCCGTTPDHIAAIAAAVAPHKPRIVPE--IEPR
LRLSGLEPFILTDAIPFVNVGERTNVTGSARFRKLVTAGDYTAALQVARDQVENGAQIIDVNMDEGLLDSEAAMVTFLNLVAAIARVPVMVDSSKFSVIE
AGLKCVQGKPVVNSISMKEDKFIHEAKVARRHGAAVVVMAFDEVGQADTFARKTEICKRAYDILNRVGFPPEDIIFDPNIFAIATGIEEGVDFIEATRWI
RKNLGAHISGGVSNLSFSFPVREAMHSVFLYHAIKAGMDMGIVNAGQMIVYDDIDPEDVILNRDPGASERLERFRGNK-QT----KEADLARE-WPVAKR
LSHALVHGITEFIEQDTEEARKASKRPLDVIEGPLMAGMNVVGDLFGDGKMFLPQVVKSARVMKQAVAWLMPFMEEEKNSSSAGKIVLATVKGDVHDIGK
NIVGIVLQCNNYEVIDLGVMVPAAKIVETVKAEKADIVGLSGLITPSLDEMAFFAGELQREGLKLPLLIGGATTSPSYR--AGPVVHVNDASRAVGVASA
LLS
>tr|Q210B6|Q210B6_RHOPB Methionine synthase (B12-dependent) OX=316056 OS=Rhodopseudomonas palustris (strain BisB18). GN= PE=3 SV=1
---LLALARE-RILVLDGAMGTMIQQLQFDEGANNDLLILTQPQAIENIHAQYLRAGADIVATNTFSSTSIAQADDLIAYEMSREGARLARNAATLPRFV
AGSIGPTNRTISPYRAVTFDDLRLAYAEQINGLLDGGADLLLVETIFDTLNAKAALYAIAEIADVPVMISGTITSGRLLSGQMPEAFWNSVRHAGPITIG
FNCALGAEDMRGHIADIGRVADTLICAYPNAGLPNE--FG--QYDETPEYMARLVGEFARDGVNIVGGCCGTTPDHIAAIAQAVAPYKPRIVPT--IEPR
LRLSGLEPFELTADIPFVNVGERTNVTGSAKFRKLITAGDYDAALQVARDQVENGAQIIDVNMDEGLLDSEAAMVTFLNLVAAIARVPVMVDSSKFAVIE
AGLKCLQGKPVVNSISMKEAKFIHEAQIARRHGAAVVVMAFDEQGQADTYARKTAICKRAYDILGQLNFPPEDIIFDPNVFAIATGLEEGVDFIEATRWI
RQNLHAHISGGVSNLSFSFPVREAMHSVFLYHAIKAGMDMGIVNAGQMIVYDDIDPEDVILNRDPGASERLEKYRGKE-QT----KEQDLARD-WPVEKR
LSHALVHGITEYIEADTEAARLTVARPLHVIEGPLMAGMNVVGDLFGDGKMFLPQVVKSARVMKQAVAYLMPFMEKEKNRKNAGKIVIATVKGDVHDIGK
NIVAIVLQCNNFEVIDLGVMVPAAKIIEAAKREGADIIGLSGLITPSLDEMSFLASEMQRNGLTIPLLIGGATTSANYP--DGAVVHVHDASRAVGVASS
LLA
>tr|A9FAG8|A9FAG8_SORC5 Methionine synthase OX=448385 OS=So ce56)). GN= PE=3 SV=1
---LQKLLQR-RIVIIDGAMGTTIRTYGMKEGQNGDLFSLTQPEMICDIHRRFLEAGADIIETNTFGATSITQSEFLLAWEINEQSARQCREWADRQRFV
AGAIGPLTVSNSPFRVVTFDQVKQAYVHQIRALIAGGSDVLLVETIFDSLNAKAALVAIREVFTLPVMISAAVGGETMISAQTVEAFWNAVKHVNPLAIG
LNCSLGPDLMYPFLSDLSEKSSAAISCYPNAGLPNP--LS--PFDLEPPDMARHIGGFADAGLNIAGGCCGNTPEHIAAIAKALAGKPPRALPE--AP-P
GRLSGSQPFTQQPGV-YMILGERTNVAGSPKFAKLIKEGKFEEAVGVARQQVENGANVIDICMDEGMIDGVSAMTRFLLLLASVAKVPFMVDSSKWEVIE
AGLRCMQGKGIVNSISLKEAKFRENARTILKYGAAVVVMAFDEQGQAATYEDKIRICKRAYGILDEVGFPPEDIIFDPNILTVATGMEEAVDFIEATRWI
KANLHAKVSGGVSNISFSFRVREAMHSAFLYHAIRAGMDMGIVNAGMLEVYEEIEPEDVLLNRRPDATERLEALKGA-AEA----EKKEEERK-GTVEER
LSHALVKGIDTYIDIDTEEARAKLGRPLSVIEGPLMDGMSVVGDLFGAGKMFLPQVVKSARVMKKAVAYLTPFMEAEKAEKTQGKIVLATVKGDVHDIGK
NIVGVVLACNNYEVIDMGVMVPCEKILERARQEKADLIGLSGLITPSLDEMIHVAREMERQNFKLPLLIGGATTSPHY---SEPVVHVVDASRAVPVTTS
LLS
>tr|I7ZHZ3|I7ZHZ3_9GAMM Methionine synthase OX=1172194 OS=Hydrocarboniphaga effusa AP103. GN=WQQ_16560 PE=3 SV=1
---LTRLLAE-RVLVLDGAMGTMIQRYKLEEGENNDLLVLTQPQIIREIHRQYLEAGADLIETNTFNAQLISLADGMLAYEMNVAAATLAREAADEPRFV
AGALGPTNRTISPFRNVSYDELVDAYLEQANGLVDGGSDILLIETIFDTLNAKAAIFACERLFRWPVMISGTITSGRTLSGQVTEAFWASVRHARPLSIG
LNCALGGKDMRPYIAELSRLADCHVSCYPNAGLPNA--FG--EYDEMPEDTAGIIREFTEAGVNIVGGCCGTSPGHIGAMARAVAGLAPRKPVE--HDGI
TKLSGLEPLNLTSAIRFVNVGERTNVTGSAKFRDLIKAGDYATALNIARQQVESGAQVVDVNMDEGMLDGVAAMERFLKLIAAISRVPVMIDSSKWEVIE
AGLKCVQGKPIVNSISMKEEKFVREARLCRQYGAAVVVMAFDEQGQADTLERRKDICGRAYKILEQVGFPPEDIIFDPNVFAVATGIEAGVDFIEAARWI
KQNLGAHISGGVSNVSFSFPVREAIHSVFLFHAINAGMDMGIVNAGALVVYDTLDAEDVILNRRADGTERLGKFKGDG-KQ----EAADEARS-LPLGER
ITHALVKGIDQYVEADTELLRAEIGRPIEVIEGPLMNGMNVVGDLFGAGKMFLPQVVKSARVMKKAVAYLIPFIEAEKPGRAKGKILMATVKGDVHDIGK
NIVGVVLQCNNYEVIDLGVMVPGQKILDAAREHEVDIIGLSGLITPSLDEMVSLAKEMQRQGFDIPLLIGGATTSPQY---QGPIVWVKDASRSVPIASA
LLS
>tr|B4X1C1|B4X1C1_9GAMM Methionine synthase OX=236097 OS=Alcanivorax sp. DG881. GN=ADG881_3094 PE=3 SV=1
---LTAQLQE-RILILDGGMGTMIQRCQFSEGTNNDLLSMTQPERIKALHKGYLDAGADIIETNSFNSTSIAMADDMLARDINVAAARVAREAADEPRYV
AGVLGPTNRTISPYRNTNFDALVNAYLEALDGLVEGGIDMVLIETIFDTLNAKAAVFAVDQYCDLPVMVSGTITSGRTLTGQTTEAFYNSLRHARPISFG
LNCALGPMELRPYIEELSRISETYVSAHPNAGLPNE--MG--EYDLDPFTMAKEVRAWAEKGLNIIGGCCGTTPEHIAAMADAVEGLAPRQLPD--IEVA
CRLSGLEPCTITKDSLFVNVGERTNVTGSKRFLRLIKEEDYDTALEVARDQVENGAQIIDINMDEGMLESAECMVKFLNLVASISKVPIMIDSSKWEVIE
AGLKCIQGKGVVNSISMKEEAFLHQARLLRRYGAAVIVMAFDEEGQADTRERKVEICTRAYKLLEEVGFPPEDIIFDPNIFAIATGIEEAVDFIEAVGDI
KRTLHAMISGGVSNVSFSFTVREAIHAVFLYYAIKNGMDMGIVNPTMLAIYADIPEEDVVLNRHEDGTEVLEKYRGSGEKA----KKEDLARE-WAVEKR
LEHALVKGVADYVEEDTELARQNAARPLHVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKKAVAYLMPFMEKEKQDEANGKILMATVKGDVHDIGK
NIVGVVLQCNGYDVVDLGVMVPCETILEVAKEEKVDIIGLSGLITPSLEEMVHVASEMQRLEMNLPLMIGGATTSPAY---NEAVVHVADASRAVGVASK
LLS
>tr|F5SNQ4|F5SNQ4_9GAMM Methionine synthase OX=1002339 OS=Psychrobacter sp. 1501(2011). GN= PE=3 SV=1
---IVEQLDQ-RILMLDGAMGTQIQTFKLQEGENNDLLVLTQPQIIKSIHTDHLAAGADIIETNTFNATQISMSDGMLVPEINREAALLARAAADEPRFV
AGVIGPTSRTLSPYRNVTFDELVDNYTEALFALIEGGIDLVLIETIFDTLNAKAAIFAVTGVFELPIMISGTITSGRTLSGQTAEAFYNSIRHAKPLSVG
FNCALGADALRPHIQTLSDIADTYVSAHPNAGLPNE--FG--EYDETPEETAALLNGFGKAGLNIVGGCCGTRPEHIKAISDVMKQYPPRQIPI--PP-A
CRLSGLEPFTITKDSLFVNVGERTNVTGSKKFLRLIKTGEFTEALDVARDQVDGGAQIVDINMDEGMLDSKGAMIHFLNLVAGISRVPLMIDSSKWDIIE
EGLKRTQGKAVVNSISLKEDEFVERAKLCMRYGAAVIVMAFDEDGQADTYERKIQICQRSYDVLNDVGFPSEDIIFDPNIFAVATGIPEGADFINATQWI
TDNLNAMVSGGVSNVSFSFPIREAINAVFLYHAIKAGLTMGIVNPAMLEVYDEIPKEDVMLNRNSGATERLEAYVAGGKND----GTVDLSRE-QSVEKR
IEHALVKGITTYIDEDTEEARLKYPKPLHVIEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKRAVAVLNPYIEAEKEGEVKGKVVMATVKGDVHDIGK
NIVGVVLGCNGYDVVDLGVMVPCDKILDTAIAEKADIIGLSGLITPSLDEMVYVAKQMQERGMDLPLMIGGATTSPNYQ--NDAVIYVSDASRSVGVVTK
LLS
>tr|Q2K667|Q2K667_RHIEC 5-methyltetrahydrofolate--homocysteine S-methyltransferase protein OX=347834 OS=Rhizobium etli (strain CFN 42 / ATCC 51251). GN= PE=3 SV=1
---LRKAASE-RILVLDGAMGTQIQGLGYDEGTNNDLLILTQPDAIEEIHYRYAKAGADILETNTFSSTRIAQADQMAVYDLNKEGAEIVRRAALRRRFV
AGAIGPTNRTISPFRAVTFDDLRSAYGEQIDGLIDGGADIILIETIFDTLNAKAAIFACEERFRLPVMISGTITSGRTLSGQTPSAFWNSVRHANPFTIG
LNCALGANAMRPHLQELSGVADTFICAYPNAGLPNE--FG--QYDETPELMAAQIDSFAREGVNIVGGCCGSTPEHIRAIAETVAKYKPRPIPE--HRPF
MSLSGLEPFELTKDIPFVNVGERTNVTGSAKFRKLITNADYTAALDVARDQVENGAQVIDINMDEGLIDSEKAMVEFLNLIAAIARVPVMIDSSKFSIIE
SGLKRVQGKPIVNSISLKEENFLAQARLLRNYGAAVVVMAFDETGQADNYDRKVEICTRAYKLLEKIGFPPEDIIFDPNIFAVATGIEEGVDFIEAARTI
RERMLVHISGGVSNLSFSFPVREAMHAVFLYHAIQAGMDMGIVNAGQLAVYDNIDPEDVVLNRRADGTERLERFRGAG-EG----RVQDLSRE-WSVEKR
LEHALVNGITEYIEADTEEARRQAARPLHVIEGPLMAGMNVVGDLFGSGKMFLPQVVKSARVMKQAVAVLLPYMEEEKNRQSAGKILMATVKGDVHDIGK
NIVGVVLACNNYEIVDLGVMVPATKILETAIAEKVDVIGLSGLITPSLDEMVHVASEMERQGFEIPLLIGGATTSPGYN--KGQAVYVTDASRAVGVVSA
LLS
>tr|Q1QDM1|Q1QDM1_PSYCK Methionine synthase (B12-dependent) OX=335284 OS=Psychrobacter cryohalolentis (strain K5). GN= PE=3 SV=1
---ITEQMAA-RILMLDGAMGTHIQNYKLEEGENNDLLVLTQPHMIKEIHLAHLESGADIIETNSFNGTRLSMADDMLVPELNKTAAKIAREAADEPRFV
AGVIGPTSRTLSPFRNITFDELVLNYREATLALMEGGVDIILIETIFDTLNAKAAIFAVTGVFELPIMISGTITSGRTLSGQTAEAFYNSIRHAKPLSVG
FNCALGADALRPHIQTLSNIANTYVSAHPNAGLPNE--FG--EYDETADETAALLEGFAKAGLNIVGGCCGTTPEHIRQIANMVAKYPPRIIPI--PP-A
CRLSGLEPFTINKDSLFVNVGERTNVTGSKKFLRLIKTEAYLEALDVARDQVEGGAQIVDINMDEGMLDSKQAMIHFVNLVSGISRVPLMIDSSKWDIIE
EGLKRTQGKCVVNSISLKEAEFVERAKLCMRYGAAIIVMAFDEDGQADTFERKTQICKRSYDVLDEVGFPSEDIIFDPNIFAVATGITEGADFINATKWI
TENLNAMVSGGVSNVSFSFPIREAINSVFLYHAIQNGLTMGIVNPAMLELYDDIPVEDVMLNRNTGATERLENYQDGGKKD----STVDMTRE-GTVEER
IAHALVKGITTFIEADTKEAWEKYPRPLEVIEGPLMDGMNIVGDLFGAGKMFLPQVVKSARVMKQSVAWLNPYIEAEKEGEKKGKILMATVKGDVHDIGK
NIVGVVLGCNGYDIVDLGVMVPCEKILDTAIAEKVDIIGLSGLITPSLDEMVYVAKQMQERGMTLPLMIGGATTSPQYQ--NNGVIYVADASRSVGVVTK
LLS
>tr|A7IJ79|A7IJ79_XANP2 Methionine synthase OX=78245 OS=Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2). GN= PE=3 SV=1
---LAQAASE-RILVLDGAMGTMIQGLKLDEGANNDLLSLTQPDAVRAIHLEYFRAGADMVETNTFSGTSIAQADGMLVYELNFESARLAREAGDIPRFV
AGAFGPTNRTISPFRAVTFDDLAGAYHEQARGLVDGGADILLVETIFDTLNAKAAIFAIEQLFRLPVMISGTITSGRTLSGQTPAAFWYSLQHARPFSIG
LNCALGAREMRAHVAEIGRVADTLVCAYPNAGLPNE--FG--MYDESPQAMAELVGEFAASGVNIVGGCCGTTPAHIRAIAEAVKGKAPRVVPQ--IEPR
LRLSGLEPFELTPEIPFVNVGERTNVTGSARFRKLITTGDFAAALAVARDQVESGAQVIDINMDEGLLDSEAAMVTFLNLVAAIAKVPVMVDSSKWEIIE
QGLKRLQGKGIVNSISMKEDAFREKARLVRSYGAAVVVMAFDEEGQADTFERKTQICARAYRILEELAFPPEDIIFDPNIFAVATGIEEGVAFIEATRWI
RQNLHAHVSGGVSNLSFSFPVREAMHAVFLYHAIQAGMDMGIVNAGQLAVYDEIEPEDVVLNRRPDATERLEGFKGAG-EK----KEADLARS-WPVDKR
LAHALVNGITDFVEADTEEARQSVARPLHVIEGPLMAGMNVVGDLFGAGKMFLPQVVKSARVMKQAVAYLMPFMEKEKMASAAGKVLMATVKGDVHDIGK
NIVGVVLQCNNYEVIDLGVMVPMAKILETAKAEKVDVIGLSGLITPSLDEMVNVAAEMEREGFSLPLLIGGATTSPRYE--RGQAVYVTDASRAVGVVSS
LLN
>tr|E8TLA7|E8TLA7_MESCW Methionine synthase OX=765698 OS=WSM1271). GN= PE=3 SV=1
---LTAAARE-RILILDGAMGTQIQGLGFNEGENNDLLILTQPGAIEEIHYQYAIAGADILETNTFSSTSIAQADGMAVYALNRDGARLVRRAAVRRRFV
AGALGPTNRTMSPYRAVTFDDLRLAYGEQLRGLIDGGADIILIETIFDTLNAKAAIFAAEEIFRLPVMISGTITSGRTLSGQTPTAFWHSVRHASPFTIG
LNCALGANAMRAHLAEISGVADTFVCAYPNAGLPNE--FG--RYDESPDFMAAQIEDFAREGVNVVGGCCGSTPEHIRAIAEAVRKYPPRAIPD--IEPR
MRLSGLEPFTLTDEIPFVNVGERTNVTGSAKFRKLITAGDYVAALDVARDQVANGAQIIDINMDEGLIDSKKAMVEYLNLIAAIARVPVMVDSSKWEIIE
AGLKCVQGKPLVNSISMKEEAFLHHARLVRAYGAAVVVMAFDEDGQADTKARKVEICTRAYKLLEQAGFPPEDIVFDPNVFAIATGIEEGVDFIEAAGEI
TATLHVHISGGVSNLSFSFPVREAMHAVFLYHAIQRGMDMGIVNAGQLAVYDTIEPEDVVLNRAPKATERMERFKGTA-EA----QERDLARE-WTVEQR
ISHALVNGITEFIDADTEEARLAAERPLHVIEGPLMAGMNVVGDLFGAGKMFLPQVVKSARVMKQAVAGLLPHMEAEKNRKTAGKILMATVKGDVHDIGK
NIVGVVLACNNYEIIDLGVMVPAARILQTAREQNVDIIGLSGLITPSLDEMAHMAAEMEREGFDIPLLIGGATTSPRYS--KGQTVYVTDASRAVGVVSS
LLS
>tr|Q2YD17|Q2YD17_NITMU Methionine synthase (B12-dependent) OX=323848 OS=Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849). GN= PE=3 SV=1
---LEDLLAR-RILLLDGAMGTMIQSHKLGEGENNDLLTLTQPQVIRSIHEAYLEAGADIVETNTFNSTAASMGDHMLVYELNFAGARLAKEAAQAPRFV
AGVLGPTTKTISPFRGITFDQLVEDYSESIRGLLDGGADILLVETIFDTLNAKAALFAIDRYFRVPIMISATITSGRTLSGQTPEAFWNSVSHARPLSVG
LNCALGAELMRPYVEELSRVAGVYVSAHPNAGLPNP--LAETGYDESPEYTAGLIKGYAQAGVNIVGGCCGTTPAHIKAIADAVGSIPPRVVPD--VPKK
LRLSGLEPLNIGDDSLFVNVGERTNVTGSKAFARLILGNNYAEALSVGRSQVENGAQIIDINMDEAMLDSQKAMVTFLNLVAAISRVPIMIDSSKWSVIE
AGLKCVQGKPIINSISLKEAEFIEHAKLARRYGAAVIVMAFDETGQADTLARKVEICARCYRILDQVGFPPEDIIFDPNIFAIATGIEEGVDFIEATRAI
KEKLYAKVSGGVSNVSFSFPVREAIHTAFLYHAVRAGMTMGIVNAGQLGVYSDIPKEDVLLNRETTATERLESFKGQS-E-----STEDLARN-GSLQER
LTHALVKGITTYIVEDTEAARQEIAAPIQVIEGPLMNGMNVVGDLFGSGKMFLPQVVKSARVMKQAVAHLLPFIEAEKSGKPKGKIVIATVKGDVHDIGK
NIVTVVLQCNNYEVVNMGVMVPSAQILETARRENADMIGLSGLITPSLEEMAHVAKEMEREGFTIPLLIGGATTSPKY---SGVTVWVPDASRAVGVCSN
LLS
>tr|D0LXL7|D0LXL7_HALO1 Methionine synthase OX=502025 OS=Haliangium ochraceum (strain DSM 14365 / JCM 11303 / SMP-2). GN= PE=3 SV=1
---LHKLMRE-RILVIDGAMGTMIQRQGLDEGTCNDLLGLTQPKLIEELHLQFLRAGADIIETNTFNANAVAMADAMQVREMNLASAQVARRAVERVCMI
AGSMGPTTKTLSPARGITYDELVTIYYEQAQALLEGGVDLLLAETSFDTLNMRAALFAIQKLFRVPVMSSATITSGRTLSGQTIAAYYQSVAHVDLSYIG
INCALGADEMRPYVEELAGLSRFPVACVPNAGLPNE--LG--EYDETPESMGALLGEFANNGLNFAGGCCGTRPEHIAAIADAVAGVAPRK-PE--PK-P
-SLSGLEPLVITPESNFTMIGERTNVTGSRKFKRLIMNDHYEEAVEVARQQVEGGANIIDVCMDEGMLESEAAMTRFLNLIAAIARVPVMIDSSKFTVIE
AGLKCIQGKGVVNSISLKEEAFKEHASLIRRYGAAVVVMAFDETGQATTVDHRLTIARRAYRILEELGFPPEDIIFDPNILTVGTGIEEAVSFIEAVRQI
KAEMLCKVSGGVSNISFSFPVREAMHAAFLYHAIKAGLDMGIVNAGQLEVYDEIEPEDVLLNRRADATERLSSYTRE-ETE----KQDVKQRT-GTLEER
MSHALVKGIADHVDEDVAEALEKYPSPLSIIEGPLMDGMNVVGGLFGEGKMFLPQVVKSARVMKKAVAILEPLMEEEKKKHAKGKMVIATVKGDVHDIGK
NIVGVVLRCNGYEVEDLGVMVPAKQILDAAREMKADVVGLSGLITPSLDEMIHVAKEMKRLKMNIPLLIGGATTSPVY---DGPSVHVGDASLAVGVLGK
LLS
>tr|B0CJ47|B0CJ47_BRUSI Methionine synthase OX=470137 OS=Brucella suis (strain ATCC 23445 / NCTC 10510). GN= PE=3 SV=1
---LTQAARE-RILILDGAMGTQIQGLGFHEGDNNDLLTLTQPKAIEEIHYAYAMAGADILETNTFSSTSIAQADGMMVYDLNRDGARLARRAALRRRFV
AGALGPTNRTLSPFRAVTFDDLRIAYSEQIRGLIDGGSDIILIETIFDTLNAKAAVFATEEVFRLPVMISGTITSGRTLSGQTPTAFWYSLRHARPFTIG
LNCALGANAMRAHLDELSGIADTFICAYPNAGLPNE--FG--QYDETPEAMAAQIEGFARDGVNVVGGCCGSTPDHIRAIAQAVAKYEPRKPAK--VPPL
MRLSGLEPFTLTKDIPFVNIGERTNVTGSARFRKLVKAGDFAAALDVARDQVANGAQIIDINMDEGLIDSEKAMVEFLNLIAAIARVPIMLDSSKWEVIE
AGLKCVQGKAVVNSISLKEEAFLHHARLVRAYGAAVVIMAFDETGQADTQARKIEICTRAYKILEQVGFPPEDIIFDPNIFAVATGIEEGVDFIEATREI
VRTLHVHISGGVSNLSFSFPVREAMHAVFLYHAIQAGMDMGIVNAGQLAVYDTIDAEDVVLNRPESATERLERFRDS--GS----READLSRE-WPVEKR
LEHALVNGITEYIEADTEEARLAAERPLHVIEGPLMAGMNVVGDLFGSGKMFLPQVVKSARVMKQAVAVLLPFMEEEKLNQSAGKVLMATVKGDVHDIGK
NIVGVVLACNNYEIIDLGVMVPSQKILQVARDEKVDIIGLSGLITPSLDEMAHVAAEMEREGFDIPLLIGGATTSSRY---EGQAVYVVDASRAVGVVSN
LLS
>tr|Q1YJL8|Q1YJL8_MOBAS Methionine synthase, 5-methyltetrahydrofolate--homocysteine methyltransferase OX=287752 OS=Manganese-oxidizing bacterium (strain SI85-9A1). GN=SI859A1_00981 PE=3 SV=1
---LRKAVSE-RILVLDGAMGTEIQLLGLGEGHNNDLLNLTQPQAIEDIHYAYAMAGADILETNTFSSTTIAQADQMQVYELNRDGARLARRACIRRRFV
AGALGPTNRTISPYRAVTFDDLRIAYGEQLRGLIDGGSDLILIETIFDTLNAKAAIFACEEIFTLPIMISGTITSGRTLSGQTPTAFWHSVRHGRPFTIG
LNCALGAAAMRDHLAEISAAADTFVCAYPNAGLPNE--FG--EYDQSPEQMAKEVEIFCEEGVNVLGGCCGSTPDHIKAVAETAARYKPRKVPT--IAPL
MRLSGLEPFTLTKEIPFVNVGERTNVTGSARFRKMIEANDLPAALDVARSQVENGAQIIDVNMDEGLIDSKQMMIDYLNLIAAIAKVPVMIDSSKFEVIE
AGLKCVQGKALVNSISMKEDAFLKQARLVRSYGAAVVVMAFDEQGQADTLERKVSICSRAYKLLEEAGFAPEDIVFDPNVFAIATGIEEGVAFIEATRQI
RQNLGAHISGGVSNLSFSFAVREAMHAVFLYHAIQAGMDMGIVNAGQLAVYESIDPEDVVLDRKRDPTERLERWRSAG-EA----KAKDLTRE-KSVQDR
IAHALVNGITEYIVEDTEEARLEADRPLHVIEGPLMDGMNIVGDLFGAGKMFLPQVVKSARVMKQAVAHLLPYMEEEKNRSNAGKVLMATVKGDVHDIGK
NIVGVVLACNNYEVIDLGVMVPAAKILETARREKVDVIGLSGLITPSLDEMVHVAAEMEREGFDIPLLIGGATTSPGYN--RGQTVYVTDASRAVGVVSH
LLS
>tr|Q0G312|Q0G312_9RHIZ Methionine synthase OX=314231 OS=Fulvimarina pelagi HTCC2506. GN=FP2506_16339 PE=3 SV=1
---LTQAVSE-RILVLDGAMGTEIQLLGLGEGHNNDLLNLTQPKQIEDIHYNYAMAGADILETNTFSSTSIAQADTMQVYELNRDGARLARRACLRRRFV
AGALGPTNRTISPYRATSFDELRQAYGEQLRGLMDGGIDLVLIETIFDTLNAKAAIFACEEIFTLPIMISGTITSGRTLSGQTPTGFWHSVRHAKPFTIG
LNCALGAEAMKDHLAEISSVADTFVCAYPNAGLPNE--FG--EYDQSPEAMGAEVEKFAKDGVNIVGGCCGSTPDHIAAVAKAVSKHSPRKVPE--KEPQ
MRLSGLEPFTLTKDIPFVNVGERTNVTGSARFRKLIKENDYPTALEVARQQVENGAQVIDVNMDEGLLDSEQAMVDYLNLIASIARVPVMIDSSKFEVIE
AGLKCVQGKGIVNSISMKEESFKKQARLVREYGAAVVVMAFDETGQADTKDRKVEICERAYRILEEVGFPPEDIIFDPNIFAVATGIEEGVDFIEAAREI
RKKMLVHISGGVSNLSFSFAVREAMHAVFLYHAIKAGMDMGIVNAGQLIVYDAIDEEDVILNRAPKATENLERYKDKG-KG----KEKDLSRE-KPVNER
LSHSLVNGITDFIEEDTEEARQNAERPLHVIEGPLMDGMNIVGDLFGDGKMFLPQVVKSARVMKQAVAYLNPYMEAEK-DEAKGKILMATVKGDVHDIGK
NIVGVVLACNNYEVIDLGVMVPAAKILEEAKKNKVDIIGLSGLITPSLDEMVNVAAEMEKQDFQVPLLIGGATTSPAYT--KGQAIHVNDASRAVGVVSS
LLS
>tr|H0HX96|H0HX96_9RHIZ B12-dependent methionine synthase OX=1107882 OS=Mesorhizobium alhagi CCNWXJ12-2. GN= PE=3 SV=1
---LRSAARE-RILFLDGAMGTQIQGLGFHEGDNNDLLILTQPQAIEDIHYAYAKAGADIIETNTFSSTRIAQADGMMVYELNRDGARLVRRAAIRRRFV
GGALGPTNRTMSPFRAITFDELRLAYGEQLRGLIDGGADIILIETIFDTLNAKAAIFAAEEIFWLPVMISGTITSGRTLSGQTPTAFWHSVRHAKPFTVG
LNCALGAAAMRPHLAELSGVADTFICAYPNAGLPNA--FG--QYDESPEFMASQVEDFAREGVNVIGGCCGSTPDHIAAIAEAVSRHKPRSVPK--VKTL
MRLSGLEPFTLTKDIPFVNVGERTNVTGSAKFRKLITAADYAAALDVARDQVANGAQIIDVNMDEGLIDSKKAMVEYLNLIAAIARVPVMIDSSKWEVIE
AGLKCVQGKPVVNSISMKEEAFLHHAKLCRMYGAAVVVMAFDQQGQADTKARKVEICTRAYKLLEQAGFAPEDIIFDPNVFAVATGIEEGVDFIEATGEI
TSTLHVHISGGVSNLSFSFPVREAMHAVFLYHAIQRGMDMGIVNAGQLAVYDTIEPEDVVLNRTPKATERMERFKGTA-EA----KERDLARD-WPVEKR
ISHALVNGITEFIDADTDEARLEAERPLHVIEGPLMAGMNVVGDLFGAGKMFLPQVVKSARVMKQAVAGLLPHMEAEKNRKTAGKILMATVKGDVHDIGK
NIVGVVLACNNYEIIDLGVMVPATKILQTAKDEKVDIVGLSGLITPSLDEMVHVASEMEREGFDIPLLIGGATTSPRYA--RGQAVHVNDASRAVGVVSA
LLS
>tr|B2ZZ99|B2ZZ99_METME Methionine synthase OX=17 OS=Methylophilus methylotrophus (Bacterium W3A1). GN= PE=3 SV=1
---LREALSQ-RILILDGAMGTMIQRYKLTEGENNELLTLTQPHVIQEIHEQYLAAGADIIETNTFGATSVAQDDHMLVYEMNVEAAKLAKAACVKPRFV
AGALGPTPKTISPARNVSFDQLVTSYLEQIRGLVEGGADILMVETIFDTLNCKAALFAIDSFFTWPIMISGTVTSGRILSGQTVTAFWHSVRHAKPLTVG
LNCALGATLMRPYAEELSKVADTFVCIYPNAGLPNP--MS--DFDETPDITASLVKEFAQSGINIAGGCCGTTPPHINAIYNAIKDLPPRQVPT--LPVT
TKLSGLEPFVIDEQSLFVNVGERTNVTGSKAFARMIINEQYEEALSVARQQVENGAQVIDINMDEGMLDAVKAMTHFLNLVASIARVPIMIDSSKWSVIE
AGLKCVQGKAIVNSISMKEAEFLRQAKLCRRYGASVIVMAFDEKGQADTFERKIEICKRAYDLLS-TGFPPEDIIFDPNIFAIATGIEEAVDFIEATRWI
KQNLYARISGGVSNVSFSFPAREAIHTVFLYHAIKAGMTMGIVNAGMVGVYDDIDPEDVVLNRVVDATERMGTLVAGG-KK----AEATLARG-TPATKR
LEYALVHGITDFIVADTEEVRQDIMRPIHVIEGPLMDGMNVVGDLFGQGKMFLPQVVKSARVMKSAVAHLIPFIEEEKAGKPKGKVVIATVKGDVHDIGK
NIVSVVLQCNNFEVVNMGVMVPAAEILEMAKRENADIIGLSGLITPSLEEMAYIAKEMQRDPHFTPLLIGGATTSPNY---EGPVIYVPDASRSVSVMQN
LLT
>tr|Q11LJ3|Q11LJ3_MESSB Methionine synthase (B12-dependent) OX=266779 OS=Mesorhizobium sp. (strain BNC1). GN= PE=3 SV=1
---LKAAARE-RILVLDGAMGTQIQGLGFDEGDNNDLLILTQPKAIEEIHYQYAIAGADIIETNTFSSTRIAQADGMMVYELNRDGARLARRAVKRRRFV
AGALGPTNRTISPYRAITFDDLRIANGEQIRGLIDGGVDIILIETIFDTLNAKAAVFAAEEVFRLPVMISGTITSGRTLSGQTPTAFWHSVRHANPFTIG
LNCALGAAAMRPHLAELSSAADTFTCAYPNAGLPNE--FG--QYDESPEAMAAQIEEFAREGVNIVGGCCGSTPEHIRAIAEAAAKHKPRELPK--PPRL
MRLSGLEPFTLSKDIPFVNIGERTNVTGSARFRKLITAGDFAAALDVARDQVANGAQVIDVNMDEGLIDSKKAMVEYLNLIAAIARVPVMIDSSKWEVIE
AGLKCVQGKPIVNSISMKEEAFLHQARLCRAYGAAVVVMAFDETGQADTKARKVEICTRAYKILEKVGFPPEDIIFDPNIFAVATGIEEGVDFIEAAREI
TKTLHVHVSGGVSNLSFSFPVREAMHAVFLYHAIHAGMDMGIVNAGQLAVYDTIDPEDVVLNRKPEATERLERYKGTG-EA----KERDLARE-WPVEKR
LEHALVNGITEFIEEDTEEARQKAERPLHVIEGPLMAGMNVVGDLFGAGKMFLPQVVKSARVMKQAVAVLLPYMEAEKNRESAGKILMATVKGDVHDIGK
NIVGVVLACNNYEIIDLGVMVPATKILQTARDEKVDIIGLSGLITPSLDEMVHVASEMEREGFDIPLLIGGATTSPRYS--QGQAIYVTDASRAVGTVSN
LLS
>tr|A6GN35|A6GN35_9BURK B12-dependent methionine synthase OX=391597 OS=Limnobacter sp. MED105. GN= PE=3 SV=1
---LRELLQK-RILILDGATGTMIQQYKLTEGENNELLVLTQPAIMTEIHEQYLAAGADILETNTFGATTVAQADDMLVDEMNREAARLCKEACIKPRFA
AGALGPTPKTISPARNITFDELVATYYQQTKGLVEGGVDLLLVETIFDTLNAKAALFAIDQYFKLPIMISGTVTSGRVLSGQTVEAFWNSVRHAKPITIG
LNCALGASLMRPYVAELSKICDVPICVYPNAGLPNP--MS--DFDETPEITSSLVKEFAAAGLNVAGGCCGTTPDHIAAIAKALENQKPRTIPT--VEPK
CRLSGLEPLNIDDNSLFINVGERTNVTGSKAFARMILNEQYDEALSVARQQVENGAQIVDVNMDEAMLDSKAAMVKFLNLMASISRVPVMIDSSKWDVIE
AGLKCVQGKAVVNSISMKEEEFKRQAKLCKRYGAAVIVMAFDEKGQADTYARKIEICERAYNILNEVGFPAEDIIFDPNIFAIATGIEEGNDFIEATGWI
KKNLHAKISGGVSNVSFSFPAREAIHTVFLYHAIKNGMTMGIVNAGMMGVYDELEPEDIVLNRQPDATERMGTLKAGG-KK----LEENLERN-QPVQKR
LAHALVHGITNFIVEDTEECRAEIARPINVIEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKQAVAHLIPYIEEEKQGKAKGKILIATVKGDVHDIGK
NIVTVVLQCNNFEVENMGVMVPAEQILAKAKEINADIIGLSGLITPSLEEMAYVASEMQRDPYFIPLLIGGATTSPHY---EGPTVYVSDASRSVGVASN
LLS
>tr|D3SCH9|D3SCH9_THISK Methionine synthase OX=396595 OS=Thioalkalivibrio sp. (strain K90mix). GN= PE=3 SV=1
---IEKALKE-RILILDGGMGTTIQLYKLEEGENNDLLSLTRPDIIEQIHNDYLEAGADIIEANTFNGTRIAMADHMLVPELNRESAKLARKAADAPRYV
AGILGPTNRTISPARNVDFDTLVESYKEAAEALVEGGVDILLIETVFDTLNAKAAIFAVKTLEELPIMISGTITSGRTLSGQTTEAFWNSVRHANPVSIG
LNCALGAKEMRQYVEELSRIADTHVSAHPNAGLPNE--FG--DYDESPEQMAADVGPWAEQGLNIIGGCCGTLPEHIRAMREAVEKFPPRKVPE--IAPA
CRLSGLEPCNITDDSLFVNVGERTNVTGSRKFLRLIQNEEYDVALEVALNQVEGGAQIIDINMDEGMLESQDAMVRFLNLLAGIARVPVMIDSSKFEIIE
AGLKCVQGKAVVNSISMKEENFIKQAQLCRRYGAAIVVMAFDEDGQADNEDRRVEICTRAYRLLEKVGFPAEDIIFDPNIFAVATGIEEGVDFIEATRRI
KQDLHALVSGGVSNVSFSFPVREAIHAVFLYHAIKAGMDMGIVNAGQLAVYDDIDEEDVVLNRRDDATERLEEYKGQG-GK----KEENLERE-WEVTKR
LEHSLVKGIDTYVVEDTEEARQQYDRPIQVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKKAVAHLIPYIEAEKGTENNGKILMATVKGDVHDIGK
NIVGVVLQCNNFEVIDIGVMQPGAEILKAAKEHDVDVIGLSGLITPSLEEMANFAADLEREGMTTPLMIGGATTSPNY---SGPVVWVKDASRAVGVAQS
LIS
>tr|C6WTP7|C6WTP7_METML Methionine synthase OX=583345 OS=Methylotenera mobilis (strain JLW8 / ATCC BAA-1282 / DSM 17540). GN= PE=3 SV=1
---LRALLAQ-RILILDGAMGTMIQQYKLTEGENNELLTLTQPAIIQEIHEKYLAAGADIIETNTFGATAVAQDDHMLVYEMNVEAAKLAKAACAKPRFV
AGALGPTPKTISPARNVNFDQLVNAYLEQTRALVEGGADILMVETIFDTLNCKAALFAIDTYFTLPIMISGTVTSGRILSGQTVTAFWHSVRHAKPLTIG
LNCALGATLMRPYVEELSSIADTFVCIYPNAGLPNP--MS--DFDETPDVTSSLVKEFAQSNLNIAGGCCGTTPAHINAIYNEIKDLPPRQLPA--LPRT
LKLSGLEPFVVDDDSLFVNVGERTNVTGSKAFARLIINEQYDEALTVARQQVENGAQVIDINMDEGMLDAIKAMTHFLNLVASIARVPIMIDSSKWSVIE
AGLKCVQGKAVVNSISMKEEEFIRQAQLCKRYGAAAIVMAFDEKGQADTFERKIEICKRAYDLLEKLDFPPEDIIFDPNIFAIATGIEEAVDFINATHWI
KQHLYAKISGGVSNVSFSFPAREAIHTVFLYHAIKAGMTMGIVNAGMMGVYDDLAPEDVVLNRVVDATERMSTLVAGG-KK----EAATLERG-TPVEKR
LSHAMVHGITEFIVDDTEEARQKVARPIHVIEGPLMDGMNVVGDLFGQGKMFLPQVVKSARVMKSAVAHLIPFIEAEKAGKPKGKMVIATVKGDVHDIGK
NIVSVVLQCNNFEVVNMGVMVPASEILAMAKAENADIIGLSGLITPSLEEMAHVAREMQRDPYFMPLLIGGATTSPHY---DGPIVYVADASRSVTVMQN
LLT
>tr|Q1GYB3|Q1GYB3_METFK Methionine synthase (B12-dependent) OX=265072 OS=Methylobacillus flagellatus (strain KT / ATCC 51484 / DSM 6875). GN= PE=3 SV=1
---LREILSK-RIMILDGAMGTMIQQYKLTEGGNNELLTFTQPQIIQEIHEQYLAAGADIIETNTFGATSVAQEDFMLAYEMNVEAARLARAACDKPRFV
AGALGPTPKTISPARNITFDQLVAAYHEQARGLVDGGADILMVETVFDTLNCKAALFAIDQYFRLPIMISGTVTSGRILSGQTVPAFWYSIRHARPLTIG
LNCALGAALMRPYAEELSRIADTFVCIYPNAGLPNP--MS--DFDEKPEDTSALLREFAESGVNIAGGCCGTTPSHIAAIAEAVRDIPPRRIPQ--IPVA
TRLAGLEPFTIDEDSLFVNVGERTNVTGSKAFARMILNEQYEEALAVARQQVENGAQVIDINMDEGMLDAVRAMTHFLNLVASIARVPIMIDSSKWAVIE
AGLKCVQGKCIVNSISMKEAEFLRQAALCRRYGAAVIVMAFDETGQADTFERKIEICKRAYDLLEKLNFPPEDIIFDPNIFAVATGIEEAVDFINATRWI
KENLHARISGGVSNVSFSFAAREAIHTVFLYHAIKAGMTMGIVNAGMIGVYDDLDPEDVVLNRREDATERMATLAAGG-KK----QEATLDRG-TPVEKR
LEYAMVHGITEFIVQDTEEARQKVMRPIHVIEGPLMDGMNVVGDLFGQGKMFLPQVVKSARVMKQAVAHLIPFIEEEKAGKPKGKMVIATVKGDVHDIGK
NIVSVVLQCNNFEVVNMGVMVPCAEILAQAKATGADIIGLSGLITPSLEEMAYVAREMQRDPYFMPLLIGGATTSPHY---DGPVIYVPDASRSVSVMQS
LLT
>tr|K2NYN8|K2NYN8_9RHIZ B12-dependent methionine synthase OX=1231190 OS=Nitratireductor indicus C115. GN= PE=3 SV=1
---LRMAARE-RILILDGAMGTQIQSLKLDEGDNNDLLILTQPKEIEEIHYRYAKAGADILETNTFSSTTIAQADAMVVYELNRDGARLAKRAAIRRRFV
AGALGPTNRTISPFRAISFDELRIAYGEQLRGLVDGGSDIILIETIFDTLNAKAAIFATEEIFRLPVMISGTITSGRTLSGQTPTAFWYSVRHARPFTVG
LNCALGAAAMRPHLAELSGVAETLICAYPNAGLPNA--FG--EYDESPEIMSAQVSEFAREGVNVVGGCCGSTPEHIAAIAEAVASHKPRSVPN--RPVQ
MRLSGLEPFTLTDDIPFVNVGERTNVTGSARFRKLITAGDYATALDVARDQVDNGAQIIDINMDEGLIDSQKVMVEYLNLVAAIARVPVMIDSSKWEVIE
AGLKCVQGKPVVNSISLKEDNFLHQARLCRAYGAAVVVMAFDETGQADTEARKVEICTRAYKILEQVGFPPEDIIFDPNIFAVATGIEEGVDYIEATRKI
TATLHVHVSGGVSNLSFSFPVREAMHAVFLYHAIQVGMDMGIVNAGQLAVYETIDAEDVVLNRQPRATERLERFKGTG-EA----KEKDLARE-WPVEKR
LEHALVNGITEFIEADTEEARLAAERPLHVIEGPLMAGMNVVGDLFGAGKMFLPQVVKSARVMKQAVAVLLPYMEEEKSRESAGRVLMATVKGDVHDIGK
NIVGVVLACNNYEIIDLGVMVPAAKILETARSENVDIIGLSGLITPSLDEMAHVAAEMEREGFDIPLLIGGATTSPRYE--RGQAVYVTDASRAVGVVSN
LLS
>tr|I5C801|I5C801_9RHIZ B12-dependent methionine synthase OX=1189611 OS=Nitratireductor aquibiodomus RA22. GN= PE=3 SV=1
---LHKAARE-RILILDGAMGTQIQGLGFDEGDNNDLLNLTQPKAIEEEHFRYAMAGADILETNTFSSTTIAQADGMMVYELNRDGARLARRAAKRRRFV
AGALGPTNRTISPYRAVTFDDLRIAYGEQLRGLLDGGADMVLIETIFDTLNAKAAIFACEEIFRLPVMISGTITSGRTLSGQTPTAFWHSVRHAKPVTIG
LNCALGAAAMRPHLAELSGVADTLICAYPNAGLPNA--FG--QYDESPETMAAQVQEFAREGINVVGGCCGSTPEHIAAIRDAVAKHPPRKIPE--RAPQ
MRLSGLEPFTLTDDIPFVNVGERTNVTGSAKFRKLITAGDYATALDVARNQVEGGAQIIDINMDEGLIDSKKAMIEFLNLVAAIARVPVMIDSSKWEVIE
AGLKCVQGKAVVNSISLKEEAFLHQANLCRMYGAAMVVMAFDETGQADTEARKVEICTRAYKLLEKAGVAPEDIIFDPNVFAIATGIEEGVDFIEATREI
IRTLHVHISGGVSNLSFSFPVREAMHAVFLYHAIQAGMDMGIVNAGQLAVYDAIDAEDVVLNRTPKATERMERFRGTG-EA----KEKDLSRE-LPVEKR
LEHALVNGITEYIDADTEEARLNAERPLHVIEGPLMAGMNVVGDLFGAGKMFLPQVVKSARVMKQAVAVLLPYMEEEKNRQSAGKILMATVKGDVHDIGK
NIVGVVLACNNYEIIDLGVMVPAAKILETAREEKVDIIGLSGLITPSLDEMVHVAAEMEREGFDIPLLIGGATTSPSYD--RGQAVHVNDASRAVGVVSN
LLS
>tr|E7RZQ6|E7RZQ6_9BURK Exopolyphosphatase OX=887898 OS=Lautropia mirabilis ATCC 51599. GN= PE=3 SV=1
---LRELLKE-RILILDGAMGTMIQQYKLGEGENNELLSLTRPDIIQEIHEKYLEAGADLIETNTFGATAVAQADHLLAYEMNVASARLARAAADKPRFV
AGALGPQPKTISPARNITFEELRAAYLEQARGLAEGGADVFLVETIFDTLNAKAALFALDELARIPVMISGTVTSGRILSGQTVEAFWNSVRHAKPLTIG
LNCALGAALMRPYIEELARKADTFVCVYPNAGLPNP--MA--EFDETPDITSALLKEFAQANVNIAGGCCGTTPAHIRAIAEAVRPLTPRVPPV--IPVA
TRLSGLEPFNIDEDSLFVNVGERTNVTGSKAFARMILNEQYDEALQVARQQVENGAQIIDVNMDEAMLDAMKAMPRFLNLIASIARVPIMIDSSKWEVIE
AGLRCVQGKAVVNSISLKEEKFLHQARLVRRYGAAAVVMAFDEQGQADTFQRKIEICKRAYDLLNEVGFPPEDIIFDPNIFAVATGIEEGNDFIRACQWI
HDNLHARISGGVSNVSFSFPAREAIHTVFLYHAIKAGLTMGIVNAGMMGVYDEVPLEDVVLNRKPDATERLQTLKDDG-GK----KEADQARK-GSVQER
ITHAMVHGITQYIVEDTEEIRQEIARPIEVIEGPLMAGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAHLLPFIEAEKAGRSRGKIVIATVKGDVHDIGK
NIVSVVLECNNFEVVNMGVMVPCAQILEKARETGADLIGLSGLITPSLEEMAFVAGEMERDEYFIPLLIGGATTSPNY---SGPVVYVPDASRSVPVAQA
LVS
>tr|G4R7K6|G4R7K6_PELHB 5-methyltetrahydrofolate--homocysteine methyltransferase OX=1082931 OS=Pelagibacterium halotolerans (strain JCM 15775 / CGMCC 1.7692 / B2). GN= PE=3 SV=1
---LTAAARE-RILILDGAMGTMIQLEKLSEGENNDLLVITEPKIIEDIHFAYAMAGADLLETNTFSGTTIAQADGMLAYELNVAGAQAAKRAAIRRRFV
AGAVGPTNRTISPFRAVSFDQLRIAYGEQIEGLIDGGSDLILIETIFDTLNAKAAVFAAEEVFRLPVMISGTITSGRTLSGQTPTAFWYSLRHAKPFTIG
LNCALGANAMRAHLGEISDIADTLVCAYPNAGLPNE--FG--EYDESPEFMASQIEGFARDGLNIVGGCCGSTPEHIAAIAQAVSKYPPRAVPQ--IEPR
LRLSGLEPFTLTDDIPFVNVGERTNVTGSARFKKLITAGDYATALDVARDQVENGAQIIDINMDEGLIDSQQVMVEYLNLVASIARVPVMIDSSKWEVIE
AGLKCVQGKAIVNSISMKEDKFREHARLCRLYGAAVVVMAFDEDGQADTKERKVEICTRAYRILDEVGFPPEDIIFDPNIFAVATGIEEGVDFIEATKEI
TETLHVHISGGVSNLSFSFPVREAMHAVFLYHAIKVGMDMGIVNAGQLAVYESIDPEDVVLNRRSDSTERMERYKGQG-EA----KAKDLSRE-KPVGER
ISHALVNGITEYIEADTEEARQSFARPLHVIEGPLMDGMNIVGELFGAGKMFLPQVVKSARVMKQAVAYLLPFMEAE-DRQSAGKILMATVKGDVHDIGK
NIVGVVLACNNYEIIDLGVMVPTQKILDTAREQKVDVIGLSGLITPSLDEMVHVAAEMEREGFDIPLMIGGATTSPRYN--RGSTIYVKDASLAVNVVSK
LLS
>tr|A9G8T0|A9G8T0_SORC5 Methionine synthase OX=448385 OS=So ce56)). GN= PE=3 SV=1
---IEELLER-RILCLDGAMGTMIQRYRLGEGENSDLLVLTRPDVISEIHGAYLDAGADIIETNTFTGTSIAQADRLLAYEINLTAAQIARKAADAPRFV
AGAMGPTPKTISPFRAVGFDELRRAFAEQVRGLVDGGVDVILAETFLDTLNMKACLVAMEEVFRLPILLSVTITSGRTLSGQTIDAFWTSVEHASPLSVG
LNCALGASDMRPYLVDLAKLARARVSCYPNAGLPNA--FG--EYDELPETTSRLLAEFAESGVNIVGGCCGTTPDHIRAIVRATADLRPRPVPE--RD-G
-RFAGLETLVIRPETNFLMIGERTNVTGSARFMELIKKGDFTTALEVALDQVRGGANLLDVNMDEGMLDSEQAMTTFLNLVATIARIPIMVDSSRWSVIE
AGLKCIQGKGIVNSISLKEEDFLEKARAVRRYGAGVVVMAFDEIGQAESVERKVAICQRAYRLLEEAGFDPQDIVFDPNILAIATGIEEAKNFIEATRII
KATCGARVSGGVSNLSFSFVVREAMHSAFLFHAIRAGMDMGIVNAGQLAVYEDIPKEDVLFNRRPDATERLEQVKGK-GKK----KELDLARD-GPVEER
LSHALVKGLVDFIEADVEEARRKYDKPLSIIEGPLMDGMKTVGELFGAGKMFLPQVVKSARVMKRAVAHLLPFMEAEKAGSSQGKIVMATVKGDVHDIGK
NIVGVVLGCNNYEVIDLGVMVHQDRILEAALREEADMIGLSGLITPSLDEMVSVAREMERRGIRLPLLIGGATTSPEF---SGTVVHVLDASRAVGVVSS
LLD
>tr|J3HQG8|J3HQG8_9RHIZ 5-methyltetrahydrofolate--homocysteine methyltransferase OX=1144343 OS=Phyllobacterium sp. YR531. GN=PMI41_03180 PE=3 SV=1
---LTKAAKE-RILILDGAMGTQIQGLNLNEGDNNDLLILTQPQAIEDIHYAYAMAGADILETNTFSSTTIAQADSMVVYELNRDGARLARRAAIKRRFV
AGALGPTNRTMSPYRAVTFDDLRIAYADQVRGLIDGGADIILIETIFDTLNAKAAIFATNEVFVLPVMISGTITSGRTLSGQTPTAFWNSVRHAQPFTIG
LNCALGANAMRAHLAEISNVADTFVCAYPNAGLPNE--FG--QYDESPEAMAAQLEGFASEGLNIVGGCCGSTPEHIKAIAEAVGKYPPRAVPD--IAIH
MRLSGLEPFTLTKDIPFVNVGERTNITGSAKFRKLITAGDYATALDVARDQVANGAQIIDINMDEGLIDSEKAMIEFLNLIAAIARVPVMIDSSKWDVIE
AGLKCVQGKPLVNSISMKEEAFLYYAKRVRAYGAAVVVMAFDTEGQADTLERKVEICTRAYELLKEAGFPPEDIIFDPNVFAVATGIEEGVAFIEATKQI
TETLHVHISGGISNLSFSFPVREAMHAVFLYHAIQVGMDMGIVNAGQLAVYESIDPEDVVLNRRDDGTERLERYKGSA-ET----RERDLARE-WTVGKR
IEHALVNGITEFIDIDTDEARLESARPLHVIEGPLMAGMNVVGDLFGAGKMFLPQVVKSARVMKQAVAVLLPHMEAEKNRESAGKVLMATVKGDVHDIGK
NIVGVVLACNNYEIIDLGVMVPATKILQTAREQNVDIIGLSGLITPSLDEMVHVAAEMEREGFDIPLLIGGATTSPRYN--QGQTIYVTDASRAVGVVSN
LLS
>tr|L0NFP6|L0NFP6_RHISP B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase OX=391 OS=Rhizobium sp. GN= PE=4 SV=1
---LQKAARE-RILVIDGAMGTQIQGLGFDEGGNNDLLILTQPNAIEEIHYRYAMAGADILETNTFSSTRIAQADEMAVYDLNRDGARLARRAALRRRFV
AGAIGPTNRTISPYRAVSFDDLRIAYGEQIDGLIDGGADIILIETIFDTLNAKAAIFACEERFRLPVMISGTITSGRTLSGQTPSAFWYSVRHANPFTVG
LNCALGANAMLPHLQELSAVADTFICAYPNAGLPNE--FG--QYDESPTDMARQIEEFAREGINVVGGCCGSTPEHIKAIAETVSRYPAREVPK--HRPF
MSLAGLEPFVLTKDIPFVNVGERTNVTGSAKFRKLITAGDYTAALAVARDQVENGAQVIDINMDEGLIDSGRAMVEFLNLIAAIAKVPVMIDSSKFEIIE
AGLKCVQGKAIVNSISLKEENFLHQARLIRNYGAAVVIMAFDEAGQADSYERKVEICERAYKLLETVGFPPEDIIFDPNIFAVATGIEEGVDFIEATRTI
REKMLVHISGGVSNLSFSFPVREAMHAVFLYHAIQAGMDMGIVNAGQLAIYENIDAEDVVLNRHDDATERLERYRGAA-EA----KAQDLTRE-WPVEKR
LEHALVNGITDFIEADTEEARLQAKRPLDVIEGPLMAGMNVVGDLFGSGKMFLPQVVKSARVMKQAVAVLLPHMEEEKARQSAGKVLMATVKGDVHDIGK
NIVGVVLACNNYEIIDLGVMVPATKILETAVAEKVDIIGLSGLITPSLDEMVHVASEMERQGFDIPLLIGGATTSPRYE--RGQAVYVTDASRAVGVVSS
LLS
>tr|J7RBS3|J7RBS3_BORP1 5-methyltetrahydrofolate--homocysteine methyltransferase OX=568706 OS=18323). GN= PE=3 SV=1
---FVRQLDK-RILILDGAMGTMIQRYKLGEGEDNELLSLVRPDVIAEIHRQYLEAGADVIETNTFGATSIAQGDDLLAYEMNLESARLARAACDAPRFV
AGALGPQPKTISPARNVTFDELRAAYVEQLNGLLDGGIDIVLIETIFDTLNAKAAIFAVEEAFRLPVMISGTVTSGRILSGQTVEAFWNSVRHARPVTIG
LNCALGAALMRPYVAELSKICDTYVCVYPNAGLPNP--MA--EFDETPADTSALLEEFAQAGVNMAGGCCGTTPEHIRAIAGKVAALTPRAVPE--VPVK
TRLSGLEALNIDDETLFVNVGERTNVTGSKMFARLVREEKYDEALAVARQQVENGAQIIDVNMDEAMLDSVACMHRFLNLIASIARVPVMIDSSKWEVIE
TGLKCVQGKAVVNSISMKEEPFRHHARLCRRYGAAMVVMAFDEQGQADSLERRKEICGRAYRILEEEGFPPEDIIFDPNVFAVATGIDEAVDFIEGARWI
RANLHARISGGISNVSFSFPMREAIHTVFLYYAIEAGLTMGIVNAGQLGVYADLAPEDVILDRPSDPTERLETVKGSG-AK----KEEDLTRT-GSVEQR
LAHALVHGITTFIVEDTEEVRQQVARTIEVIEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKQAVAHLIPFIEEEKQGRAKGKIVIATVKGDVHDIGK
NIVSVVLQCNNFEVVNMGVMVPCAQILQKAKDENADMIGLSGLITPSLEEMAYVASEMQRDPYFMPLMIGGATTSPNY---DGPVIYVPDASRSVGVATS
LMS
>tr|F7XAA6|F7XAA6_SINMM 5-methyltetrahydrofolate--homocysteinemethyltransferase OX=707241 OS=Sinorhizobium meliloti (strain SM11). GN= PE=3 SV=1
---LAQAAAE-RILIMDGAMGTEIQQLGFVEGENNDLLTLTQPKAIEDIHYHYAIAGADILETNTFSSTRIAQADGMMVYDLNRDGARLARRAAKRRRFV
AGALGPTNRTISPYRAVSFDDLRLAYAEQVRGLIDGGADIILIETIFDTLNAKAAIFATQEVFRLPVMISGTITSGRTLSGQTPTAFWYSVRHADPFTIG
LNCALGANAMRAHIDELSAVADTLVCAYPNAGLPNE--FG--RYDESPEQMAAQVEGFARDGVNIVGGCCGSTPAHIRAIAEAVAKYPPRRVPE--IDRR
MRLSGLEPFTLTDEIPFVNVGERTNVTGSAKFRKLITAGDYAAALDVARDQVANGAQIIDVNMDEGLIDSKQVMVEFLNLVASIARVPVMIDSSKWEVIE
AGLKCVQGKALVNSISLKEAAFLHHARLVRAYGAAVVVMAFDEKGQADTKTRKVEICRRAYRLLEEVGFPPEDIIFDPNIFAVATGIEEGVDFIEATHEI
IAALHVHVSGGVSNLSFSFPVREAMHAIFLYHAIQAGMDMGIVNAGQLAVYDAIDPEDVVLNRRADSTERLERYRGKG-QG----KEKDLARE-WPVEKR
LEHALVNGITEFIEADTEEARLAAERPLHVIEGPLMAGMNVVGDLFGSGKMFLPQVVKSARVMKQAVAVLLPHMEEEKNRESAGKILMATVKGDVHDIGK
NIVGVVLACNNYEIIDLGVMVPSAKILEVAREQKVDIVGLSGLITPSLDEMAHVASELEREGFDVPLLIGGATTSPRYS--LGQTVYVTDASRAVGVVSS
LLS
>tr|F4GR48|F4GR48_PUSST Methionine synthase OX=1007105 OS=Pusillimonas sp. (strain T7-7). GN= PE=3 SV=1
---FARLLGE-RILILDGAMGTMIQQYKLSEGENNELLSLVRPDIITAIHREYLEAGADVIETNTFGATAIAQGDGLLAYELNVESARLARAACDEPRFV
AGAMGPQPKTISPARNVTFEQLRDAYTEQLNGLLDGGIDIVLIETIFDTLNAKAAIFAVETVFRLPVMVSGTVTSGRILSGQTVEAFWNSVRHARPITIG
LNCALGAALMRPYVAELSKICDTYLCVYPNAGLPNP--MA--EFDETPQDTSSLLEEFAQAGVNMAGGCCGTTPEHIRAIADKVASLPVRQVPQ--VPVK
TRLSGLEALNIDADSLFVNVGERTNVTGSKMFLRLIREEKYDEALAVARQQVENGAQIIDINMDEAMLDSAVCMRRFLNMIASIARVPIMIDSSKWEVIE
QGLRCVQGKAVVNSISMKEAAFLEHARLCRKYGAAAIIMAFDEKGQADNLQRRKDICERAYRLLDEVGFPPEDIIFDPNVFAIATGIEEAVDFIEATAWI
TQNLHARVSGGVSNVSFSFAMREAIHAVFLYYAIQQGMTMGIVNAGQLGVYQDIDKEDVVLDRATDSTERLETIKGSG-AK----KEEDLSRE-QAVEGR
ISHALVHGITAFIVEDTEEVRAKIARPIQVIEGPLMDGMNIVGDLFGAGKMFLPQVVKSARVMKQAVAHLIPFIEEEKQGRSKGKIVIATVKGDVHDIGK
NIVSVVLECNNFEVVNMGVMVPCSEILAKAKEENCNMVGLSGLITPSLEEMAYVASEMQRDEYFLPLLVGGATTSPNY---EGPVIYVPDASRSVGVATN
LMS
>tr|J0B1M7|J0B1M7_ALCFA B12-dependent methionine synthase OX=1156918 OS=Alcaligenes faecalis subsp. faecalis NCIB 8687. GN= PE=3 SV=1
---FARRLGQ-QILILDGAMGTMIQRYKLGEGENNELLSLVRPDIIREIHDQYLAAGADVISTNTFGATDIAQGDDLISYDLNLASAQLACQARDAPRFV
AGALGPQPKTISPARNVTFEQLRVAYTEQVRALLDGGVDILLIETVFDTLNAKAAVFALETVFRVPVMVSGTVTSGRILSGQTVEAFWNSMRHARPITIG
LNCALGAALMRPYVAELSKICDTYVCVYPNAGLPNP--MA--EFDETPADTSSLLQEFTQAGVNMVGGCCGTTPEHIAAIAELCRKLPPRVVPE--VPVK
TRLSGLEPLNIDEDTLFVNVGERTNVTGSKAFLRLIQQENYEEALSVARQQVENGAQIIDINMDEGMLDSAACMHRFLNMIASIARVPIMIDSSKWDVIE
TGLRCVQGKAIVNSISMKEEPFLEHARLCRKYGAAIVVMAFDEQGQADSYERRVEICERAYRLLDEVGFPPEDIIFDPNVFAVATGMDEGLDFIRGVGWI
HKNLHARLSGGISNVSFSFAMREAIHTVFLYYAIQEGLTMGIVNAGQLGVYADIEPEDVILNRATDPTERLESVKGSG-AK----KEEDLSRE-TTVEQR
LIHSLVHGITTFIVEDTEEVRQKIARPISVIEGPLMDGMNVVGDLFGQGKMFLPQVVKSARVMKQAVAHLVPFIEEEKQGRSKGRMVIATVKGDVHDIGK
NIVSVVMQCNNFEVVNMGVMVPCAEILAKAKEVEADIVGLSGLITPSLEEMAYVASEMQRDPYFIPLMIGGATTSPHY---DGPVIYTPDASRCVGVATQ
LVS
>tr|C4ULI3|C4ULI3_YERRU Methionine synthase OX=527005 OS=Yersinia ruckeri ATCC 29473. GN=yruck0001_1770 PE=3 SV=1
---LHQQLAE-RILVLDGGMGTMIQSYRLEEGANNDLLVLSKPEVITAIHNAYLEAGADILETNTFNSTTIAMADQMLSAEINYEAARLARLCADEPRYV
AGVLGPTNRTISPFRNVSFDQLVEAYRESTRALVEGGVDIIMIETVFDTLNAKAATFAVESEFMLPVMVSGTITSGRTLSGQTTEAFYHSLRHVKPLSFG
LNCALGPDELRQYIAELSRISECYVSAHPNAGLPNA--FG--EYDLEAKEMAEQIGEWARAGLNIVGGCCGTTPRHIAAMVKAVAGVPPRPLPK--IPVA
CRLAGLEPLTIDASTLFVNVGERTNVTGSARFKRLIKEEKYDEALDVARQQVESGAQIIDINMDEGMLDAEAAMVRFLNLIAGIARVPIMIDSSKWDVIE
KGLKCIQGKGIVNSISMKEAAFIHHARLVRRYGAAMVVMAFDEAGQADTRARKIEICRRAYKILETVGFPPEDIIFDPNIFAVATGIEEAVDFIEACADI
KAELHAMISGGVSNVSFSFPVREAIHAVFLYYAIRNGMDMGIVNAGQLAIYDDLSDEDVVLNRRDDSTERLEKYRGS-KSD----EVAQAERG-WPVAKR
LEYSLVKGITEFIELDTEEARQEATRPIEVIEGPLMAGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAYLEPYIEASKRGTTAGKILLATVKGDVHDIGK
NIVGVVLQCNNYEIIDLGVMVPTEKILRTAREENVDIIGLSGLITPSLDEMVNVAKEMERQGFTLPLLIGGATTSQNY---SGSTTYVSNASRSVGVVSA
LLS
>tr|Q0FP39|Q0FP39_9RHOB Dihydropteroate synthase, DHPS:Homocysteine S-methyltransferase:Cobalamin-dependent methionine OX=314265 OS=Pelagibaca bermudensis HTCC2601. GN=R2601_27141 PE=3 SV=1
---LHAAARE-RILILDGAMGTQIQQLGLSEGCNNDLLNLTKPEAIEEIHYLYAMAGADIAETNTFSSTTIAQADAMAVYDLNFQGARLARRAMDRPRFV
AGALGPTNRTISPYRAVTFDQLRIAYADQARALIDGGADLLLIETIFDTLNAKAAIFACEEVFRLPVMISGTITSGRTLSGQTPTAFWHSVRHAEPFTIG
LNCALGAEAMRPHLAEISGVADTLICAYPNAGLPNE--MG--EYDETPEQMAAQIAGFAKEGLNVVGGCCGSTYEHIRAIAKAVEGFAPREIPQ--PKPL
MRLSGLEPFMLTEDIPFVNVGERTNVTGSAKFRKLITNADYATALDVARDQVENGAQIIDVNMDEGLIDSQQAMVEFLNLIAAIARVPIMIDSSKWEIIE
AGLKCVQGKPVVNSISMKEEAFLEQATLCRRYGAAVIVMAFDETGQADTEDRKVEICTRAYKLLEKVGFPPEDIIFDPNVFAVATGIEEGVDFIEATRRI
TTDCHVHISGGVSNLSFSFPVREAMHAVFLYHAIQNGMDMGIVNAGQLAVYDQIDAEDVVLNRTPAATENMERYRGQG-KG----REKDMSRE-LPVEKR
LEHALVNGITEFIEGDTEEARQAAERPLHVIEGPLMAGMNVVGDLFGAGKMFLPQVVKSARVMKQAVAVLLPYMEEEKGREAAGKVLMATVKGDVHDIGK
NIVGVVLACNNYEIIDLGVMVPAERILATAKEQNVDVIGLSGLITPSLDEMVHVASEMEREGFDIPLLIGGATTSPRYG--KGQAVYVTDASRAVSVVSS
LLS
>tr|H8Z7S6|H8Z7S6_9GAMM 5-methyltetrahydrofolate--homocysteine methyltransferase OX=631362 OS=Thiorhodovibrio sp. 970. GN=Thi970DRAFT_03536 PE=3 SV=1
---LQERLAR-SILILDGAMGTMIQRHKLDEGENNDLLVLTQPEIIKGIHSEYLAAGADIIETNTFNGTRIAMADGMLVYEINLAAAKLARQAADEPRFV
AGILGPTNRTISPFRNVDFDTLVSAYAEATRALIEGGVDILLIETIFDTLNAKAAAFGVWQVFERPILLSGTITSGRTLTGQTTEAFYNSLRHAQPLSIG
LNCALGPSELRPYVEELSRIAECQISAHPNAGLPNE--LG--GYDLGPEDMAKEVSEWARSGLNIIGGCCGTTPDHIRAMAEAVAGMAPRQAPT--ISPA
CRLSGLEPCNITEDSFFVNVGERTNVTGSARFKRLIKEGDYDTALSVAVEQVENGAQVIDVNMDEGLLDAVAAMKRFLNLTAAIARVPVMIDSSKWEVIE
TGLKCVQGKAIVNSISMKEDKFIEQARLCRRYGAAVIVMAFDEVGQADTQARKVEICTRAYKLLEQVGFPAEDIIFDPNIFAVATGIEEAVDFIEATREI
KRTLHALVSGGVSNVSFSFPVREAIHCVFLYHAVKAGMDMGIVNAGQLAIYDDLPEEDVIQNRRPDATERLPKYQGDGTAE----KAEDQERS-WPVEKR
LEHSLVKGITDFIDEDTEAARAAADKPLEVIEGPLMAGMNVVGDLFGEGKMFLPQVVKSARVMKKAVAYLFPYLEAEKASTSYGKFLIATVKGDVHDIGK
NIVAVVLQCNGYEVVDLGVMVPTETILKRAREEQVDMIGLSGLITPSLDEMVHVAKEMERQGFDIPLLIGGATTSPQR---KHPVVYVVDASRAVGVVSN
LLS
>tr|G4E615|G4E615_9GAMM Methionine synthase OX=765914 OS=Thiorhodospira sibirica ATCC 700588. GN=ThisiDRAFT_1744 PE=3 SV=1
---FKEHAAR-RILLLDGAMGTMIQRYSLSEGENNDLLVLSRPEIIREIHAKYLEAGADIIETNSFNATRISMADAMLVVELNREAARLARAVADEPRFV
AGVLGPTSRTISPFRNVYFDDLVAIYQQAATALVEGGADILMIETVFDTLNAKAAVFALEGLFRVPVMISGTITSGRTLSGQTTEAFWNSLRHARPLAFG
LNCALGPLELRPYVEELSRISDCMVSAHPNAGLPNA--FG--GYDLSPEQMATEIADWAREGLNIVGGCCGTTPEHIRAIRDAVVIHAPRTIPV--RPPA
CRLAGLEPLNIYHNNLFVNVGERTNVTGSARFKRLIKDGDYATALEVAASQVTNGAQIIDINMDEGMLDTQAAMERFLNLVAAISRVPIMIDSSKWEVIE
AGLKRIQGKGIVNSISLKEAQFIAQAQLLRRYGAAVVVMAFDEQGQADTRERKIEICSRAYRILEQADFPAEDIIFDPNIFAVATGIEEAVDFIEATAAI
RKTLHALISGGVSNISFAFAVREAIHAVFLYHAIRAGLSMGIVNAGQLAVYDEIQPEDVILNRHPEATERLQQYRSSG-ET----RTEDLSRD-WPVAKR
LEHALVKGVDTYVVADTEAARLEAGHPIQVIEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKKAVAHLIPYIEADRQGQKQGRILMATVKGDVHDIGK
NIVGVVLQCNNFEVIDLGVMVPAQKILDQAKAQQVDIIGLSGLITPSLDEMVHLASEMQRLGFEIPLLIGGATTSPHY---QGPCVWVKDASRAVGVAQS
LLS
>tr|A9CV91|A9CV91_9GAMM 5-methyltetrahydrofolate--homocysteine methyltransferase OX=314608 OS=Shewanella benthica KT99. GN=KT99_06597 PE=3 SV=1
---LTRQLEQ-GILILDGAMGTMIQDLKLQEGENNDMLVLTQPAAIKGIHKQYLLAGADIIETNTFNSTRIAMADDMFSAQINLEGARLARAAADESCYV
AGVLGPTNRTISPYRNVTFDELVEAYVESINALIEGGADIIMLETIFDTLNAKAALFAVETVYRLPIMISGTITSGRTLTGQTTEAFYNSLRHVKPLSIG
LNCALGPKELRPYVEELAKIAECFVSAHPNAGLPNE--FG--GYDETPKQMADIIGEWAQEGLNIIGGCCGTTPEHIRVIREAVIKYPARPLPD--IPVA
CRLAGLEPLTIDENSLFLNVGERTNVTGSAKFLRLIKGGEFEEALSVARDQVENGAQIIDINMDEGMLDGSEIMHKFLNLIASISRVPIMIDSSKWEVIE
AGLKCIQGKGIVNSISLKEEKFIQQATLVKRYGAAAIIMAFDEQGQADTKARKIEICTRAYRVLDKVGFPPEDIIFDPNIFAIATGIEEAVDFIEATAEI
KRTLHAMISGGVSNVSFSFPVREAIHAVFLYHAIQAGMDMGIVNAGQLAIYDDIDPEAIVGNLPTNNTELLEKFRGDGQTT----KKADLERS-WEVNKR
LSHALVKGITDYIIQDTEEARAASSRPLDVIEGALMDGMNVVGDLFGSGKMFLPQVVKSARVMKKSVAYLNPYIEEEKPGQSNGKILMVTVKGDVHDIGK
NIVGVVLACNGYDVIDLGVMVPVEKIIDVAIAENVDIIGMSGLITPSLDEMVHNVKSFHKAGLTIPIIIGGATCSPHS---PTGAIYIADASRAVPMVSK
LIN
>tr|L0GVF5|L0GVF5_9GAMM 5-methyltetrahydrofolate--homocysteine methyltransferase OX=765912 OS=Thioflavicoccus mobilis 8321. GN=Thimo_0495 PE=4 SV=1
---LEDQIKR-RILLLDGAMGTVIQGYKLTEGENNDLLVLTQPQIIAEIHGRYLEAGADIIEANSFNATRVAMADGMLVPEINREAARLARAAADDPRFV
AGILGPTNRTISPHRNIYFDELVAAYRESAAALIEGGTDLLLIETVFDTLNAKAAVFALEGLFRWPVMISGTITSGRTLTGQTTEAFWNSLRHARPFSFG
LNCALGPKELRPYVEELSRIADTHISAHPNAGLPNA--FG--GYDETPEQMAEEIGGWAAAGLNIIGGCCGTTPEHIRAIAAAVERHAPRTVPE--ISPA
CRLAGLEPFNIGEGSLFVNVGERTNVTGSARFKRLIKDGDYETALEVAAGQVENGAQVIDVNMDEGMLDAVATMRRFLFLAAAIARVPVMIDSSKWEVIE
TGLKCIQGKGIVNSISLKEENFIRQARLVRRYGAAVIVMAFDEQGQADTQARKVEICARAYRILEQVGFPAEDIIFDPNIFAVATGIEEGVDFIEATRQI
KGQLYALISGGVSNVSFSFPVREAIHAVFLYHAIQAGMDMGIVNAGQLAVYDEIDPEDVVLNRRPDATERLERFRGGG-EA----KKEDLERG-WPVAQR
LEHALVKGIDAFVVEDTEEARQQFDRPIHVIEGPLMDGMNRVGDLFGAGKMFLPQVVKSARVMKKAVAHLIPYIEAEKEGGNNGRILMATVKGDVHDIGK
NIVGVVLQCNNFEVIDIGVMVPAQQILDTAREKKVDVIGLSGLITPSLEEMVHVASEMQRLGLEIPIMLGGATTSPSY---TGSTVWVKDASRAVGVAQS
LIS
>tr|K9DR69|K9DR69_9BURK Methionine synthase OX=883126 OS=Massilia timonae CCUG 45783. GN=HMPREF9710_03082 PE=4 SV=1
---LREILAR-RIMILDGAMGTIIQQYKLDEGENNELLTLTQPQVIQEIHERYLAAGADLLETNTFGATGVAQEDHMLAYEMNVEAARLARAACDKPRFV
AGALGPTPKTISPARNITFDQLVASYHEQVRGLVDGGADLLLVETIFDTLNCKAALFAIDQYFRLPLMISGTVTSGRILSGQTVPAFWNSVRHAKPLTIG
LNCALGAALMRPYAQELSQIADTFVCIYPNAGLPNP--MS--DFDELPADTSALLREFADAGINIAGGCCGTTPEHIAAIAKILETQAPRQVPE--VPVA
MRLSGLEPFTIDESSLFVNVGERTNVTGSKAFARMILNEQFDEALSVARQQVENGAQVIDINMDEAMLDSQAAMTRFLNLIASISRVPVMIDSSKWSVIE
AGLKCVQGKAIVNSISMKEEEFIRQARLCRRYGAAVIVMAFDEQGQADTFARKIEICERAYKVLEQVGFPPEDIIFDPNIFAIATGIEEANDFIEACAWI
RDNLHAKISGGVSNVSFSFPAREAIHTVFLYHAIKAGLTMGIVNAGMVGVYDDLDPEDVVLNRRKDATERMGTLKAGG-AK----QEQNLERN-APVEKR
LAHALVHGITQWIVEDTEEMRQQVARPIHVIEGPLMDGMNIVGDLFGQGKMFLPQVVKSARVMKQAVAHLVPFIEEEKAGKPKGKMVIATVKGDVHDIGK
NIVSVVLQCNNFEIVNMGVMVPCADILAKAKEENADMVGLSGLITPSLEEMAHVAREMQRDPWFVPLLIGGATTSPHY---DGPVVYVPDASRSVSVGQA
LVT
>tr|C8Q0K3|C8Q0K3_9GAMM Methionine synthase OX=553217 OS=Enhydrobacter aerosaccus SK60. GN= PE=3 SV=1
---LAELLKQ-RILFLDGAMGTEIQNYKLIEGENNDLLVLTQPHIIRDIHRSYLEAGADIIETNSFNGTQISMADGMLAYEINKSAAALARQVCDEPRFV
AGVIGPTSRTISPFRNVTFDELVDNYTEATYALIEGGADIILIETVFDTLNAKAAIFAVTGVFELPIMISGTITSGRTLSGQTAEAFYNSIRHAKPISIG
FNCALGADALKPHIKTLSDVCETFVSAHPNAGLPNE--FG--EYDETPEQTATMVADYAKSGVNIVGGCCGTTPKHIAKIVEMTSPFAPRQLPY--KP-A
CRLSGLEAFNITRDSLFVNVGERTNVTGSKKFLRLIKNEEYTEALDVARDQVEGGAQVVDINMDEAMLDSKAAMIHFVNLVASISRVPLMIDSSKWDIIE
AGLKCTQGKSVVNSISLKETEFVQKAKLCQRYGAAIIVMAFDEDGQADSFERKIEICKRSYDILDEVGFPSEDIIFDPNIFAVATGIEEGLDFINATRWI
TDNLNAMVSGGVSNVSFSFPIREAIHAVFLYHAIKNGMTMGIVNPAMLELYDDIDPEDVILNRNSGATDHLENYLSG-KKD----STVDLSRE-LPVEKR
IEHALVKGITTYINEDTEEARLKFPRPLDVIEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKQAVAWLNPYIEKEKAGETKGKVLMATVKGDVHDIGK
NIVGVVLGCNGYDIIDLGVMVPCEKILQVAKDENVDIIGLSGLITPSLDEMVYVAKQMQEQGFNLPLLIGGATTSPNYQ--NDAVVYVADASRAVGVATT
LLS
>tr|I1AVG6|I1AVG6_9RHOB B12-dependent methionine synthase OX=766499 OS=Citreicella sp. 357. GN= PE=3 SV=1
---LEKAASD-RILILDGAMGTQIQQLGLAEGCNNDILNLTAPDKVEEIHYLYAMAGADIVETNTFSSTTIAQADDMAVHDLNVAGARIARKAMDRARFV
AGALGPTNRTISPYRAVSFDDLRAAYAEQLHGLIEGGIDIVLIETIFDTLNAKAAIFACEEVFRLPVMISGTITSGRTLSGQTPTAFWHSVRHAQPWTIG
LNCALGADAMRPHLAEISGVADTLTCAYPNAGLPNE--MG--EYDQTPEEMADLIAGFAREGLNVVGGCCGSTYDHIAAVAKAVEGHAPRAIPA--HKPL
MGLSGLEPFTLTSDIPFVNVGERTNVTGSARFRKLVTNADYAAALDVARDQVENGAQIIDINMDEGLIDSKQAMVEFLNLIAAIARVPIMIDSSKWEIIE
AGLKCVQGKSVVNSISMKEEAFLHQATLCRRYGAAVIVMAFDEKGQADTEDRKVEICTRAYKLLEQVGFPPEDIIFDPNVFAVATGIEEGVDFIEATRRI
TTDCHVHISGGVSNLSFSFPVREAMHAVFLYHAIQNGMDMGIVNAGQLAVYDQIDAEDVVLNRTPAPTENLERYRGKD-KG----REKDLSRE-LPVEKR
MEHALVNGITEYIDADTEEARLQADRPLHVIEGPLMAGMNVVGDLFGAGKMFLPQVVKSARVMKQAVALLLPYMEEEKNRESAGKVLMATVKGDVHDIGK
NIVGVVLACNNYEIIDLGVMVPAEKILATARAEGVDVIGLSGLITPSLDEMVHVASEMERTGFDIPLLIGGATTSPRYG--KGQAVYVTDASRAVGVVSS
LLS
>tr|G4DHB8|G4DHB8_9GAMM Methionine synthase OX=713587 OS=Thioalkalivibrio thiocyanoxidans ARh 4. GN=ThithDRAFT_1061 PE=3 SV=1
---IQQALAE-RILILDGGMGTMIQEYRLEEGENNDLLVLTRPDVIQAIHGDYLEAGADIIETNTFNGTRIAMADAMLVPELNREAARIAREAADAPRFV
AGVLGPTNRTISPYRNVDFDTLVANYRESAAALIEGGVDLLLIETVFDTLNAKAAVFAVETLFRVPVMISGTITSGRTLSGQTTEAFWNSLRHARPLSIG
LNCALGPKELRAYIEELSRIANTHVSAHPNAGLPNE--FG--DYDETPEQMAVEIGEWAASGLNIIGGCCGTTPDHIRAIAAAVQAHPPRRMPE--IAPA
CRLSGLEPLNITEDSLFVNVGERTNVTGSKRFARLIREEDYETALEVAKDQVENGAQVIDINMDEGMLDSQAAMQRFLNLIAGIARVPIMIDSSKWEILE
AGLKCIQGKGVVNSISLKEEKFIEQARLVRRYGAAVIVMAFDEQGQADTAERKLEICTRAYQILERIGFPAEDVIFDPNIFAIATGIEEGVDFIEATRAI
KERLHALISGGVSNVSFSFPVREAIHAVFLYHAIHAGMDMGIVNAGQLAVYDEIEPEDVVLNRRSDATERLERYRGSG-AA----KKEDLERS-WPVAKR
LEHSLVKGIDSYVVEDTEEARLEAERPIHVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKKAVAHLIPFIEAEKGCENNGRILMATVKGDVHDIGK
NIVGVVLQCNNFEVIDLGVMVPAQKILETAREKNVDVIGLSGLITPSLEEMAHVAAEMQRQGFDTPLLIGGATTSPNYG--AGPVVWVKDASRAVGVAQS
LIS
>tr|F9TWC9|F9TWC9_MARPU Methionine synthase OX=765910 OS=Marichromatium purpuratum 984. GN=MarpuDRAFT_0346 PE=3 SV=1
---IRERLER-SILILDGAMGTMIQRHGLTEGENNDLLVLTQPEVIVGIHRDYLEAGADIIETNTFNATSVAMADGMLAREINVEAARLARVAADAPRFV
AGVLGPTNRTISPKRNIDFDTLVAAYAESTRGLIEGGADLILIETIFDTLNAKAAVFAVRQVFERPIMLSGTITSGRTLTGQTTEAFYNSLRHAEPLSVG
LNCALGPSELRPYVEELSRIAECHVSAHPNAGLPNE--LG--GYDLDPETMAGQVSEWARSGLNIVGGCCGTTPDHIRAIAAAVAEVSPRQRPE--IAPA
CRLSGLEPLNIGADALFVNVGERTNVTGSARFRRLIKEEDYDTALSVALEQVENGAQVIDVNMDEGLLDAVAAMRRFLNLVAAIARVPVMVDSSKWEVIE
TGLKCVQGKPIVNSISLKEEKFLHQARLCRRYGAAVIVMAFDEVGQADTRARKVEICTRAYRLLEQVGFPPEDIIFDPNIFAVATGIEEAVDFIEAVAEI
KRTLHAKISGGVSNVSFSFPVREAIHAVFLYHAIRAGMDMGIVNAGQLAIYDDLPEEDVVLNRGAEATERLPEYQGGGGES----RQQDQERS-WPVEKR
LEHALVKGITEYIDEDTEAARQALGRPLHVIEGPLMAGMNHVGDLFGAGKMFLPQVVKSARVMKKAVAYLFPFLEAERASQNNGRILMATVKGDVHDIGK
NIVGVVLQCNNYEVIDIGVMVPAETILQRAREEQVDIIGLSGLITPSLDEMVHVAKELERQGMEMPLLIGGATTSPQR---EAPVIYVPDASRAVGVASN
LLS
>tr|A3V5M8|A3V5M8_9RHOB Probable 5-methyltetrahydrofolate--homocysteine methyltransferase OX=314232 OS=Loktanella vestfoldensis SKA53. GN=SKA53_15401 PE=3 SV=1
---IAAAAAD-RILILDGAMGTQIQALGFAEAHNNDLLILTQPQAIEDIHYTYAMAGADIVETNTFSSTSIAQADGLLVYDLNFHGARLVRQALDRMRFV
AGALGPTNRTMSPYRAVTFDQLRVAYVEQLRGLIDGGADLILIETIFDTLNAKAAIFACEEIFRLPVMISGTITSGRTLSGQTPTAFWHAVRHADPLTIG
LNCALGAAEMRAHLAELSGVADTLICAYPNAGLPNE--FG--AYDESPAFMAEQIAAFAKEGVNIVGGCCGSTPDHIRAIAAAVAGHKPRAIPA--QTPL
MRLSGLEPFTLTRDIAFVNVGERTNVTGSAKFRKLITARDYAAAVDVAREQVENGAQIIDVNMDEGLIDSKQAMIDYLNLIAAIARVPVMIDSSKWEVIE
AGLQCVQGKPIVNSISMKEEAFLHQARLCRAYGAAVVVMAFDEAGQADTEDRKVAICTRAYQLLQKVGFPPEDIIFDPNVFAVATGIEEGVDFINATRRI
KADLHVHVSGGVSNLSFSFPVREAMHAVFLYHAIQAGMDMGIVNAGQLAVYDSIDPEDVVLNRTPD-TENMERFKSTG-EA----KERDLARE-WSVEKR
LEHALVNGITEFIDADTDEARLRADRPLHVIEGPLMAGMNVVGDLFGAGKMFLPQVVKSARVMKQAVAVLLPYMEEEKNRESAGKVLMATVKGDVHDIGK
NIVGVVLACNNYDIIDLGVMVPAAKILEVAKAENVDIIGLSGLITPSLDEMVHVAAEMERAGMDIPLLIGGATTSPNYA--RGQTLYVTDASRAVGVVSA
LLS
>tr|A0P544|A0P544_9PROT B12-dependent methionine synthase OX=383631 OS=Methylophilales bacterium HTCC2181. GN= PE=3 SV=1
---LKDILSN-RIMMMDGAMGTMIQQHHLTEGKNNELLSITQPTIIQQIHESYLDAGSDIIETNTFGANSIAQDDYMLVYEMNIESAKLAKNAANKPRFV
AGAIGPTPKTISPARNINFDQLVASYKEQTKALIEGGVDIILVETVFDTLNCKAALFAVNAVFRLPLMISGTVTSGRILSGQTVSAFWNSIRHAKPLTIG
LNCALGAALMRPYAEELSKIADTYICIYPNAGLPNP--MS--DFDEKPQDTSLLLKDFADSGINIAGGCCGTTPDHIRAIAEEVKSIKPRIVPI--QETY
TRLAGLEPLAIKEDMLFINVGERTNVTGSKAFAKLIIEEQFEEAVSVARQQVENGAQVIDINMDEGMLDSLQAMQHFLNLIASIARIPIMIDSSKWEVIE
AGLKCVQGKAIVNSISLKEESFIHQAQLCLNYGAAIIVMAFDEKGQADTYERKIEICKRAYDTLNDLNFPPEDIIFDPNIFAVATGIEEAVDFINATQWI
KDHLHAKISGGVSNVSFSFLAREAIHTVFLHHAIKAGLTMGIVNAGMIGLYDDLSEEDVILNRRPDATERMGTLKGS--KK----EELKLNRG-DEVEKK
IEYALVHGVTDFIVEDTEEARLKIMRPINVIEGPLMDGMNVVGDLFGQGKMFLPQVVKSARVMKQAVAHLVPFIEKEKRGKPKGKMLIATVKGDVHDIGK
NIVSVVLQCNNFEVVNMGVMVPCAEILAKAKEENVDIIGLSGLITPSLEEMTHVASEMQRDPYFIPLLIGGATTSEHY---DGPVIHVSDASRSVSIMQS
LMD
>tr|D3RTP5|D3RTP5_ALLVD Methionine synthase OX=572477 OS=(Chromatium vinosum). GN= PE=3 SV=1
---IRERLAR-SILILDGAMGTMIQRHGLTEGANNDLLVLTRPDVIGGIHRAYLEAGADIVETNSFNATRIAMADGMLAYEINVAAARLALAAADDPRFV
AGVLGPTNRTISPARNVDFDTLVAAYAESTRGLIEGGADLILIETIFDTLNAKAAIFAVKQVFERPTMISGTITSGRTLTGQTTEAFYNALRHAEPISIG
LNCALGPFELRQYVEELARISETHVSAHPNAGLPNE--LG--GYDLGPDEMAEEIAEWARSGLNIVGGCCGTTPDHIRAIAQAVAGIAPRARPE--IAPA
CRLSGLEPCNIDAGSFFVNVGERTNVTGSARFRRLIKEGDYDTALSVAQEQVENGAQVIDVNMDEGLLDAVAAMKRFLNLVAAIARVPVMIDSSKWEVIE
TGLKCVQGKPIVNSISIKEEKFLQQARLCRRYGAAVIVMAFDEAGQADTQARKIEICTRAYRLLEQVGFPPEDIIFDPNIFAVATGIEEAVDFIEATREI
KRTLHALVSGGVSNVSFSFPVREAIHAVFLYHAVKAGMDMGIVNAGQLAIYDDLPEEDVILNRRPDGTERLPKYKGDGGVE----NKADLERG-WPVEKR
IEHALIKGITDFIDEDTEAARQALGRPLEVIEGPLMRGMNIVGDLFGEGKMFLPQVVKSARVMKKAVAYLQPFLEAEKESSSNGKFLIATVKGDVHDIGK
NIVAVVLQCNSYEVIDLGVMVPTETILQRAREVGADVIGLSGLITPSLDEMVHVAKEMQRQGMNVPLLIGGATTSPQR---EAPVIYVPDASRAVGVVSS
LLS
>tr|H1G3C9|H1G3C9_9GAMM B12-dependent methionine synthase OX=519989 OS=Ectothiorhodospira sp. PHS-1. GN= PE=3 SV=1
---LHQEIQR-RIMILDGGMGTMIQGYGLQEGANNDLLVLTQPGIIREVHAAYLEAGADILETNTFNATRIAMADGMLVPEINREAARLAREVADEPRYV
AGILGPTNRTISPFRNVWFDELVAAYREAAEALLDGGVDILMIETVFDTLNAKAAVFAVEGLFRWPVMISGTITSGRTLTGQTTEAFWNSLRHARPFSIG
LNCALGPKELRPYVEELSRIADTHVSAHPNAGLPNE--FG--GYDETPAQMAEEISEWAGSGLNIVGGCCGTTPDHIRAIREAVEKHPPRPVPE--IAPA
CRLSGLEPFNITADTLFVNVGERTNVTGSARFKRLIKDGDYETALEVAAEQVESGAQVIDVNMDEGMLDALEAMKRFLCLAAAISRVPVMIDSSKWEVIE
TGLKCIQGKGIVNSISLKEDIFIRQARLLRRYGAAVVVMAFDETGQADTEDRKVEICRRAYQILEVVGFPAEDIIFDPNIFAVATGIEEGVDFIEATRRI
KQTLHALVSGGVSNVSFSFPVREAIHAVFLYHAIRAGMDMGIVNAGQLVVYDEIEPEDVVLNRRPDGTERLDRFRDTG-ET----RKEDLARS-LPVAKR
LEHALVKGIDAYVVEDTEEARLTFDRPIHVIEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKKAVAHLIPYIEAEKDDKNNGRILMATVKGDVHDIGK
NIVGVVLQCNNFEVIDLGVMVPAQKILEAAREHKVDVIGLSGLITPSLEEMTHLAAELQREGFGTPLMIGGATTSPAY---EGVTVWVKDASRAVGVAQS
LVS
>tr|C3XC26|C3XC26_OXAFO B12-dependent methionine synthase OX=556269 OS=Oxalobacter formigenes OXCC13. GN=OFBG_01780 PE=3 SV=1
---LREIMSK-RILVLDGAMGTMIQRYGLTEGENNELLSLTQPHIISAIHEEYLKAGADVIETNTFGATSIAQSDHMLVYEMNVQSAKIAREICDKPRFV
AGSIGPTPRTISPARNVTFDQLVEAYLEQIRGLVEGGADLLLVETVFDTLNCKAALFAIDTFFKLPIMISGTVTSGRILSGQTVTAFWYSIRHARPLTVG
LNCALGAALMRPYVEEISRIADTHICIYPNAGLPNP--MS--EFDELPEDTSAFLKEFAESGINVVGGCCGTTPDHIRAIAKAVTPLPPRKVPT--IPPA
MRLSGLEPFTIDDSSLFVNVGERTNVTGSKAFARMILNEEYDNALAVARQQVENGAQIIDINMDEAMLDSVSAMHRFLNLIASISRVPVMLDSSKWEVIE
AGLKCLQGKSIVNSISLKNEEFIHHAKLCRRYGAAIIVMAFDEKGQADTYQRKIDICKRAYDLLNQIGFPSEDIIFDPNIFAIATGIEEAVDFIEATRWI
RDNLNARISGGVSNVSFSLPAREAIHTVFLYHAISAGMTMGIVNAGMMGVYDEIPEEDAVLNRREDATERLGEFQSGA-KK----EGENLQRE-DSVNKR
LSYAFVHGVTDFIIEDTEEALQDTLKPIEVIEGPLMDGMNAVGDLFGQGKMFLPQVVKSARVMKQAVAHLIPYIEEEKQGQSNGKIVIATVKGDVHDIGK
NIVAVVLQCNNFEVINLGVMVPCEEILAKAKEVNADAIGLSGLITPSLEEMMYVAGEMQRDEYFIPLFIGGATTSPNY---EGPVVHVTDASRTVTVIQA
LLS
>tr|A6SU92|A6SU92_JANMA 5-methyltetrahydrofolate--homocysteine methyltransferase OX=375286 OS=Janthinobacterium sp. (strain Marseille) (Minibacterium massiliensis). GN= PE=3 SV=1
---LRDLMAR-RILILDGAMGTMIQQYKLTEGTNNELLSLTRPDVISQIHEQYLAAGADLIESNTFGATTVAQDDHMLAYEMNVASARLARAACDKPRFV
AGALGPTPKTISPARNVTFDQLVAAYLDQTRGLVEGGADVLLVETIFDTLNCKAALFAIDQFFRFPIMISGTVTSGRILSGQTVPAFWHSIRHARPLTVG
LNCALGAALMRPYAEELSKIADTYVCIYPNAGLPNP--MS--DFDETPDVTSSLLKDFAESGVNVAGGCCGTTPDHIKAIAETVKTIAPRVIPT--VEPT
LKLSGLEPFIIDDQSLFVNVGERTNVTGSKAFARLIINEQYDEALAVARQQVENGAQIIDINMDEAMLDSQAAMSRFLNLVASIARVPIMIDSSKWSVIE
AGLKCVQGKAIVNSISMKEEKFLHEAKLCRRYGAAVIVMAFDEKGQADTFERKIEICERAYWLLNEVAFPPEDIIFDPNIFAIATGIEEAVDFINSVRWI
KENLHAKISGGVSNVSFSFPAREAIHTVFLYHAIKAGMTMGIVNAGMVGVYDNLPEEDVVLNRREDATERMSTLKAGD-KK----EEATLERS-GTVQQR
LAHALVQGITQWIVEDTEEARQELLRPIHVIEGPLMDGMNIVGDLFGQGKMFLPQVVKSARVMKQAVAHLIPFIEEEKLGKPKGKIVIATVKGDVHDIGK
NIVSVVLQCNNFEVVNMGVMVPCSEILAKAKEENADIIGLSGLITPSLEEMAYVAKEMQRDEYFTPLLIGGATTSHNY---DGPVVYVPDASRSVSVAQS
LLT
>tr|G2DYV6|G2DYV6_9GAMM Methionine synthase OX=765913 OS=Thiorhodococcus drewsii AZ1. GN=ThidrDRAFT_1315 PE=3 SV=1
---IRERLER-SILILDGAMGTMIQRHGLTEGENNDLLALTRPDVIEGIHRQYLEAGADIIETNSFNATSVAMADGMLAYEINVAAARLARQAADAPRFV
AGVLGPTNRTISPYRNIDFDTLVTAYADSTRGLIEGGADIILIETIFDTLNAKAAVFAVRKVFELPIMISGTITSGRTLTGQTTEAFYNSLRHADPLSIG
LNCALGPSELRQYVEELARIAECRVSTHPNAGLPNE--LG--GYDLGPEEMATEIAEWARSGLNIIGGCCGTTPDHIRAIAAAVEGMAPRPLPD--IAPA
CRLSGLEPFNIGAETLFVNVGERTNVTGSARFKRLIKEEDYDTALSVAQEQVENGAQVIDVNMDEGLLDAVAAMQRFLNLVAAIAKVPVMIDSSKWEVIE
TGLKCVQGKPIVNSISLKEEKFLHQAHLCRRYGAAVIVMAFDEVGQADTQARKIEICTRAYKILEQVGFPAEDIIFDPNIFAVATGIEEAVDFIEAVREI
KRTLHAKISGGVSNVSFSFPVREAIHAVFLYHAIHAGMDMGIVNAGQLAIYDDLPEEDVILNRRDDGTERLPNYQGGGVEA----RPEEQERS-WPVEER
LKHSLVKGITDYIDQDTEEARLELGRPLLVIEGPLMAGMNHVGDLFGAGKMFLPQVVKSARVMKKAVAYLFPYLEAEKASKNNGRILMATVKGDVHDIGK
NIVGVVLQCNSYEVIDIGVMVPADTILQRAREENVDIIGLSGLITPSLDEMVHVAKEMERSGMAMPLMIGGATTSPQR---EAPVIYVPDASRAVGVASN
LLS
>tr|I4YVF0|I4YVF0_9RHIZ 5-methyltetrahydrofolate--homocysteine methyltransferase OX=754501 OS=Microvirga sp. WSM3557. GN=MicloDRAFT_00045170 PE=3 SV=1
---LREAASK-RILVLDGAMGTELQRSRFSEGENNDLLILTQPDAVRSVHLDYFRAGADIVETNTFSGTSIAQADGMIVYELNFEGSRLAREAALIRRFV
AGAIGPTNRTISPYRAVTFDQVREAYAEQARGLVDGGAEIILIETIFDTLNAKAAIVATHQVFKLPVMISGTITSGRTLSGQTPTAFWHSVRHAEPFSIG
LNCALGAREMRAHIQEIGKVADTLVCAYPNAGLPNE--FG--LYDESPAATARMIAEFADAGVNVVGGCCGTTPDHIRAIAEAVAGKAPRSVPK--MQPL
MRLSGLEPFTLTSDIPFVNVGERTNVTGSAKFRKLITNNDYAAALDVARDQVANGAQIIDVNMDEGLLDSEKAMVEFLNLVAAIARVPVMVDSSKFHVIE
AGLKCIQGKAIVNSISMKEDSFIEHARICRSYGAAVVVMAFDEQGQADTLERKVEICTRAYKILEQVGFPPEDIIFDPNVFAVATGIEEGVAFIEATRII
RETLHAHISGGVSNLSFSFPVREAMHSVFLFHAIKVGMDMGIVNAGQLAVYDEIDPEDVVLNRRPDATERLPRFKDGA-AV----KAADLERS-WPVGKR
IEHALVNGITEFIEQDTEEARQAAERPLHVIEGPLMAGMNVVGDLFGAGKMFLPQVVKSARVMKQAVAYLMPFMEAEKSRSAAGKVLMATVKGDVHDIGK
NIVGVVLACNNYEVIDLGVMVPAQKILETARKEKVDVIGLSGLITPSLDEMVNVASEMEREGFDIPLLIGGATTSPNYN--KGQAVYVTDASRAVGIVSS
LLS
>tr|A6FWT9|A6FWT9_9DELT 5-methyltetrahydrofolate--homocysteine methyltransferase OX=391625 OS=Plesiocystis pacifica SIR-1. GN=PPSIR1_04833 PE=3 SV=1
---LQALMRE-RIVMLDGAMGTMLQGYSLGEGENNDLLSLTRPDIVREVHRIYFESGADIVETNTFSSTSIAQADNLLARELNVASARLAREAADAPRFV
AGAIGPTNRTLSPYRAIDFATLRDAYAEQIDGLIEGGVDLLLIETIFDTLNAKAAIMAMFEVFEIPLMISVTVTSGRTLSGQTIGAFWRSVAHAKPLSVG
LNCALGASAMRPYVAELAELAGCAVSCYPNAGLPNA--FG--EYDELPEQTAAELGEFVSSNVNIVGGCCGTSPQHIETIAEFVEGKAPRAIPE--VD-G
AHFSGLEPLTIDGNTGFVMVGERTNVTGSRKFCKLIKANDYDRALSVAVQQVRSGANILDVNMDEGMLDSEQAMRTFLNLIASVARVPIMIDSSKWSVIE
AGLECVQGKAIVNSLSLKEADFLAKAAVVQRHGAGLVVMAFDETGQAESAARKLEICSRAYTLLERLDFEPTDIIFDPNVLAVATGIEEALEFIEACRGI
KQACGARISGGISNLSFSFLVREAIHSAFLYHAIAAGLDMGIVNAGQLEVYAEIEPEDVLFVRRPDATDRLEGLKGK-KKE----RKIDLSRE-QSVGAR
MAHALVHGITDFIEDDTEEARQTLGRPLEVIEGPLMDGMKVVGDLFGAGKMFLPQVVKSARVMKRAVAYLTPYMEDEQEEEPQGRVVLATVKGDVHDIGK
NIVAVVLRCNNYEVHDLGVMVPADKILESAKENRADIIGLSGLITPSLDEMVHVAKEMQRLDFATPLLIGGATTSPHF---GEPTVHVLDASRVVNVVSD
LMD
>tr|C7CDH6|C7CDH6_METED B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase OX=661410 OS=dichloromethanicum (strain DM4)). GN= PE=3 SV=1
---LRQRASE-KILVLDGAMGTVIQRLKYTEGENNDLLILTQPDAIRQIHLDYFLAGADVCETNTFSGTTIAQADGMIIHELNAEGARLAREAAKLRRFV
AGAIGPTNRTISPYRAVTFDGVKQAYVEQVRGLIDGGAELILIETIFDTLNAKAAIAAAWQVFRLPIQISGTITSGRTLSGQTPAAFWNSLRHSSPLTFG
LNCALGAKEMRGHIAELSRICDTLVCAYPNAGLPNE--FG--LYDESPEAMGKLVGEFAASGVNMVGGCCGTTPDHIRAIAEAVADKKPREIPE--IPRL
MRLSGLEPFVLTKEIPFVNVGERTNVTGSAKFRKLITNNDYAAALDVARDQVAAGAQVIDVNMDEGLLDSEKAMVEFLNLVAAIARVPVMVDSSKFEVIE
AGLKCIQGKPIVNSISMKEAKFIEAAKICRSYGAAVVVMAFDEQGQADSYERKVEICTKAYKILEQVGFPPEDIIFDPNIFAVATGIEEGVAFIEATRTI
RETLHAHISGGVSNLSFAFPVREAMHAVFLFHCIKAGMDMGIVNAGQLAVYDEIPAEDVVLNRREDSTERLERFKGAS-QA----KTADLTRE-APVAKR
IEHALVNGITEYIVSDTEEARKEAARPLHVIEGPLMAGMNVVGDLFGSGKMFLPQVVKSARVMKQAVAYLEPFMEEEKNRQAAGKVLMATVKGDVHDIGK
NIVGVVLACNNYEIIDLGVMVPAAKILETAKRENVDIVGLSGLITPSLDEMVHVAAEMEREGMEMPLLIGGATTSPAYA--KGQAVYVTDASRAVGVVSS
LIS
>tr|B8GLZ0|B8GLZ0_THISH Methionine synthase OX=396588 OS=Thioalkalivibrio sp. (strain HL-EbGR7). GN= PE=3 SV=1
---LETHIKE-RILILDGAMGTMIQGYGLGEGENNDLLALTRPEIIAEIHGQYLEAGADILETNTFNATTIAMADAMLVPEINREAARLARRVADEPRFV
AGVLGPTNRTISPFRNVDFDQLVAAYRQAAEALIEGGADLLLIETVFDTLNAKAAVFAVESLFRLPVMISGTITSGRTLSGQTAEAFWNSLRHARPFSFG
LNCALGPRELRAHVEEISRIANTHVSAHPNAGLPNE--FG--GYDLSPADMAVHIREWAESGLNIVGGCCGTTPAHIRAIAEAVADLPPRSIPK--REPA
CRLSGLEPCNITEDSLFVNVGERTNVTGSARFKRLIKDGDYETALEVAASQVENGAQIIDVNMDEGMLDSKAAMVRFLNLMAAISRVPVMIDSSKWEVIE
AGLKCIQGKGVVNSISLKEATFIEHAKLVRRYGAAVIVMAFDEQGQADTQARKVEICERAYRILEQVCFPAEDIIFDPNIFAIATGIEEGVDFIEATREI
KKRLHALVSGGVSNVSFSFPVREAIHAVFLYHAIHAGMDMGIVNAGQLAVYDEIDREDVVLNRRPDATERLERYRGEG-EA----KKEDLERK-LPVAKR
LEHALVKGIDAFVVEDTEEARQGVDHPIHVIEGPLMDGMNVVGDLFGDGKMFLPQVVKSARVMKKAVAHLIPFIEALKEGRPNGKVLMATVKGDVHDIGK
NIVGVVLQCNNFEVIDLGVMVPAQKILDTAVEQDVDVIGLSGLITPSLEEMAHMAKEMQRLGMKLPLLIGGATTSPHY---EGPTVWVKDASRAVGVVQS
LIS
>tr|A1B3D4|A1B3D4_PARDP Methionine synthase (B12-dependent) OX=318586 OS=Paracoccus denitrificans (strain Pd 1222). GN= PE=3 SV=1
---MRAAARD-RILILDGAMGTQIQQLGLSEGHNNDLLNLTQPKAIEEIHYRYAKAGADIVETNTFSSTTIAQADGMAVYDLNFHGARIARQALDRPRWV
AGALGPTNRTISPYRAVTFDDLRIAYAEQIRGLIDGGADLILIETIFDTLNAKAAIFACEEVFRLPVMISGTITSGRTLSGQTPTAFWYSMRHAAPITVG
LNCALGAAAMRPHLAELSTVADTLICAYPNAGLPNE--MG--QYDETPEEMAAQVAEFAREGVNVVGGCCGSTPEHIAAIARAVADLPPRAIPE--IEPR
LRLSGLEPFVKTDDIPFVNVGERTNVTGSARFRKLITNGDYAAALDVARDQVENGAQIIDVNMDEGLIDSKQAMIDYLNLIAAIARVPVMIDSSKWEVIE
AGLKCVQGKAIVNSISLKEEGFLNQARLCRRYGAAVVVMAFDETGQADTENRKVEICSRAYDLLNAVGFPPEDIIFDPNIFAVATGIEEGVDFIGATRRI
TQALHVHVSGGVSNLSFSFPVREAMHAVFLYHAIQAGMDMGIVNAGQLAVYDQIDAEDVVLNRQPKATENMERFRGEG-KA----REKDLTRT-WPVAKR
LEHALVNGITEYIDEDTEEARLSVERPLHVIEGPLMAGMNVVGDLFGSGKMFLPQVVKSARVMKQAVAHLLPYMEAEKASSSAGKVLMATVKGDVHDIGK
NIVGVVLACNNYEIIDLGVMVPATKILETAKAENVDIIGLSGLITPSLDEMVHVASEMEREGFDIPLLIGGATTSPRYG--RGQAVYVTDASRAVGVVGS
LLS
>tr|J6LL60|J6LL60_9RHOB 5-methyltetrahydrofolate--homocysteine methyltransferase OX=1187851 OS=Rhodovulum sp. PH10. GN=A33M_3833 PE=3 SV=1
---LRAIARE-RILVLDGAMGTQIQDLKLDEGENNDLLILTKPDAIRAIHLAYFRAGADIVETNTFSSTSIAQADGLIVFELNEQGARLAREAAIARRFV
AGSIGPTNRTISPFRAITFDQLREAYVEQVRGLLAGGADLLLIETVFDTLNAKAAIVAIEEVLQVPLMISGTITSGRMLSGQTPEAFWNSVRHAKPLSIG
LNCALGAKEMRAHIAEISRVADTLVCAYPNAGLPNE--FG--LYDESPEAMAEMLGEFADAGLNIVGGCCGTTPAHIRAIADAVSGKAPREAAR--PKPF
LRLSGLEPFTLTPEIPFVNVGERTNVTGSAKFKKLIKSGDYATALSVARDQVENGAQVIDVNMDEGLLDSKEAMTTFLNLVASIARVPVMVDSSKFEVIE
AGLKCLQGKAIVNSISLKEAAFVEHARTVRRYGAAAVVMAFDEQGQADTVARKTGICKRAYDILNQVGFPPEDIVFDPNIFAVATGIEEGLDFIEAVRWI
RENLGAHVSGGVSNLSFSFRVREAMHSVFLYHAIAAGMDMGIVNAGQMAVYDDLDPEDVILARRADASERLEKYRGET-QA----EKATLERG-WPVEKR
LTHALVHGITDFISEDVEAARQAANRPLDVIEGPLMAGMNVVGDLFGAGKMFLPQVVKSARVMKQAVAYLMPFMEEEKNRSAAGKIVLATVKGDVHDIGK
NIVGVVLQCNNYEVVDLGVMVPAAKILEAAKAEQADVIGLSGLITPSLDEMVNVASEMERQGFSVPLLIGGATTSPRYR--RGQTVYVNDASRAVGVVSS
LLS
>tr|B6BW08|B6BW08_9PROT Methionine synthase OX=314607 OS=beta proteobacterium KB13. GN= PE=3 SV=1
---LKAELKK-RILFMDGAMGTMIQQHQFVEGENNELLSITQPAVIQKIHEDYLAAGADIIETNTFGANSVAQEDFMLVKEMNIESVKLAKAAAEKPRFV
AGAIGPTPKTISPARNITFDQLFDSYAEQAETLISNGADIILIETVFDTLNCKAAIAAVQSTFTLPIMISGTVTSGRILSGQTVTAFWNSIRHAKPLTIG
LNCALGAALMRPYAEELSNIADTFVCIYPNAGLPNP--MS--DFDEKPDDTSTLLKEFAESGVNVAGGCCGTTPEHIAAITQSLKNIPPRTLPT--IVKK
MRLSGLEPMIIGDDDLFVNVGERTNVTGSRVFAKLIIDENYEEAVSVARQQVENGAQVIDINMDEGMLDAEKAMTTFLNLIASISRVPIMIDSSKWSVIE
AGLKCIQGKPIVNSISLKEESFIHQAKLCMQYGAAVIVMAFDEEGQADTYERKIEICERAYNILDTVGFPVEDIIFDPNIFAIATGIAEAVDFINATKWI
KDNLHAKISGGVSNVSFSFAAREAIHTVFLNHAIKNGMTMGIVNAGMIGVIDDLTEEDVVLNHREDATDRMGSLQGK--KK----EKDTNERG-SDVEKK
IEYALIHGITNYIEEDTETARLQIMRPINVIEGPLMDGMNVVGDLFAEGKMFLPQVVKSARVMKQAVAHLIPFIEKEKEGKPKGKMLIATVKGDVHDIGK
NIVSVVLQCNNFEVVNMGVMVPCAEILNKAKEENVDIIGLSGLITPSLEEMAHVASEMQRDPYFMPLLIGGATTSPNY---EGPVVHVADASRSVSVMQS
LLS
>tr|G8PUV3|G8PUV3_PSEUV B12-dependent methionine synthase OX=911045 OS=Pseudovibrio sp. (strain FO-BEG1). GN= PE=3 SV=1
---LEAAAKE-RILVLDGAMGTMIQNLQFSEGENNDLLILTQPDAIRDIHLQYLKAGADIIETNTFSSTSIAQADAMIVYELNKEGARLCCEAVEQRRFV
AGGLGPTNRTISPFRAVSFDDLKDSYAEATRGLIDGGCDLILVETIFDTLNAKAALFAIDEVFKLPVMISGTITSGRTLSGQTPEAFWNSVRHAAPFTVG
LNCALGAKEMRAHVDEISRVADTLVCAYPNAGLPNE--FG--EYDESPEYMAGLLKEFAEAGVNVVGGCCGTTPEHIKAVADAVEGLPPRALPE--VPRL
MRLSGLEPFTFTKDVNFVNVGERTNVTGSARFRKLIKNDDYTTALDVARSQVENGAQIIDINMDEGLLDSEEAMVTFLNLIAAIAKVPVMIDSSKWTVIE
AGLKCVQGKAVVNSISLKEENFIAQAKLIRRYGAAVVVMAFDETGQADTLQRKIEICKRSYDVLDKVGFGPEDIIFDPNIFAVATGIEEGVDFIEATRWI
SENLYAHISGGVSNLSFSFPVREAMHSVFLYHAIQAGMDMGIVNAGQLAVYDDLPAEDVVLNRRSDSTDRLEKFKGAG-KK----REVDLTRE-GTVEKR
LEHSLVHGITDFIVEDTEEARQKADRPLHVIEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKAAVAYLMPYLEQEKLSSSNGKILMATVKGDVHDIGK
NIVGVVLQCNNFEVIDLGVMVPTAKIIDEAKKHNVDIIGLSGLITPSLDEMCHVASEMEREGLDIPLLIGGATTSPNYS--KGQAIYVTDAGRAVGVASR
LMA
>tr|B8IH83|B8IH83_METNO Methionine synthase OX=460265 OS=Methylobacterium nodulans (strain ORS2060 / LMG 21967). GN= PE=3 SV=1
---LRKRAAE-RILVLDGAMGTMIQRLKLGEGKNNDLLILTQPDAIRQIHLDYFLAGADVAETNTFSGTVIAQADGMIVRELNREGARLAREAAAERRFV
AGAVGPTNRTISPYRAVTFDQVRDAYAEQVRGLIEGGSDLVLIETIFDTLNAKAAIAATWQVFRLPIMISGTITSGRTLSGQTPTAFWHSLRHAEPLTFG
LNCALGAREMRAHISELSRVCDTLVCAYPNAGLPNE--FG--LYDESPEAMAALVGEFAGSGVNMVGGCCGTTPDHIRAIAEAVAGKAPRRVPE--VPRL
MRLSGLEPFTLTKEIPFVNVGERTNVTGSAKFRKLITNGDYAAALDVARDQVAAGAQVIDVNMDEGLLDSAAAMVEFLNLVAAIARVPVMVDSSKFAVIE
AGLKCIQGKPIVNSISLKEEKFIHEAKVCRSYGAAVVVMAFDEKGQADTLARKVEICTRAYRILDEVGFPPEDIVFDPNIFAVATGIEEGVAFIEAARQI
RQTLHAHISGGVSNLSFAFPVREAMHAVFLYHAIHAGMDMGIVNAGQLAVYDELDPEDVVLNRRSDATERLARFKGGG-QV----RTADLARE-APVEKR
LEHALVNGITEYIEADTEEARAKAARPLDVIEGPLMAGMNVVGDLFGSGKMFLPQVVKSARVMKQAVAYLMPFMEAEKNRQAAGKVLMATVKGDVHDIGK
NIVGVVLACNNYEIIDLGVMVPAAKILDTARKEKVDIVGLSGLITPSLDEMVHVASEMEREGFDVPLLIGGATTSPAYA--RGQAVYVTDASRAVGVVSS
LLS
>tr|A8HVP5|A8HVP5_AZOC5 5-methyltetrahydrofolate-homocysteine methyltransferase OX=438753 OS=Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / ORS 571). GN= PE=3 SV=1
---LLAAARD-RILVLDGAMGTMIQGLKLDEGANNDILNLTRPDDVRAIHLKYFLAGADIVETNTFSSTTIAQADAMLAYELNVEGARLAKEAAIEPRFV
AGAIGPTNRTISPFRATSFDELATAYAEQTRGLIAGGSDIILIETIFDTLNAKAAVFAAETVFRLPVMISGTITSGRTLSGQTPSAFWYSLRHAQPFSIG
LNCALGAKEMRAHIAELGRVADTFVCAYPNAGLPNE--FG--LYDESPEAMAELVGEFAASGVNIVGGCCGTTPDHIGAIAKAVAGKAPRAIPT--LEPR
LRLSGLEPFELTREIPFVNVGERTNVTGSARFRKLITNGDFTAALDVARDQVESGAQVIDVNMDEGLLDSHAAMVTFLNLVAAIARVPVMVDSSKWDIIE
AGLKCIQGKGIVNSISMKEDAFRHYARLVRRYGAAVVVMAFDEKGQADTYERKIEICARAYKILEEIGFPPEDIIFDPNVFAVATGIEEGVNFIEATRWI
RQNLHAHISGGVSNLSFSFPVREAMHAVFLYHAIQAGMDMGIVNAGQLAVYDEIPAEDVVLNRNADATERLEGFKGGG-EK----READLTRT-WDVEKR
LAHALINGITEYVEADTEEARAAAARPLHVIEGPLMSGMNIVGDLFGAGKMFLPQVVKSARVMKQAVAYLMPFMEKEKMASAAGKILMATVKGDVHDIGK
NIVGVVLQCNNYEVIDLGVMVPAAKILEVAKAEKVDVIGLSGLITPSLDEMVTVASEMEREGFHVPLLIGGATTSPQYH--RGQAVYVTDASRAVGVVSN
LLS
>tr|G9AQA0|G9AQA0_PANAN B12-dependent methionine synthase OX=1123863 OS=Pantoea ananatis LMG 5342. GN= PE=3 SV=1
---LHQQLAH-RIMVLDGGMGTMIQSYKLDEGSNNDLLVLSKPEVIREIHDAYLAAGADILETNTFNATSIAMADQMLSAEINFAAAKLARTCADAPRYV
AGVLGPTNRTISPFRNITFNQLVDAYRESTRALVEGGCHIIMIETVFDTLNAKAAVFAVKAEMALPLMISGTITSGRTLSGQTTEAFYNSLRHAEPLSFG
LNCALGPDELRQYVAELSRIAEGYVTAHPNAGLPNA--FG--EYDLDAEVMAQQIGEWANAGLNIVGGCCGTTPQHIAAMAAAVEGVAPRQRPK--LPVA
CRLSGLEPLNISAESLFVNVGERTNVTGSAKFKRLIKEDKYHEALEVALQQVESGAQIIDINMDEGMLDAEAAMVRFLNLIAGIARVPIMIDSSKWEVIE
KGLQCIQGKGIVNSVSMKEAVFIHHARLIRRYGAAMVVMAFDEVGQADTRERKIEICRRAYQILQQVGFPPEDIIFDPNIFAVATGIDEAMDFIGACEDI
KRELHAMISGGVSNVSFSFPVREAIHAVFLYYAIRNGMDMGIVNAGQLAIYDDLSDEDVILNRRADGTERLEKYRRN-KSD----SADQAERG-WDVVKR
LEYSLVKGITEFIEQDTEEARQQAARPIDVIEGPLMSGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAWLEPYIQASKAGRSNGKVVLATVKGDVHDIGK
NIVGVVLQCNNYEIIDLGVMVPGEKILKTAREVKADIIGLSGLITPSLDEMVNMAKEMERQGFTLPLLIGGATTSQHY---SGPTVYVQNASRTVGVVSS
LLS
>tr|B3PL28|B3PL28_CELJU Methionine synthase OX=498211 OS=cellulosa). GN= PE=3 SV=1
---LYQAIRE-RILILDGGMGTMIQSYKLKEGANNDLLSITKPEVIRDIQRAYLDAGADILETNTFNATRISMADDMLVPELNYAAARLARELCDEPRFV
AGVLGPTSRTISPARNVTFDQLVENYVEATDSLVKGGADIILIETVFDTLNAKAAVFAVQQYFELPIMISGTITSGRTLSGQTTEAFYNSLAHARPLSMG
LNCALGAKELRQYVQELSRVANCFVSAHPNAGLPNE--FG--EYDQTAQEMVEIVEEFAASGLNIIGGCCGTTPAHIKAIADAMAKYPPRPLPA--IEPA
CRLSGLEPFNITRDSLFVNVGERCNVTGSARFKRLIVEEDYTTALEVALEQVENGAQVIDINMDEGMLDAEKAMVRFLNLIAGIARVPIMVDSSKWEVIE
AGLKCIQGKPIVNSISLKEEEFLHKAKLCMRYGAAVVVMAFDETGQADTMARKMEICARSYRTLDKLDFPPEDIIFDPNIFAVATGIEEAVDFIEATRWI
RTHLHAGVSGGVSNVSFSFPVREAIHSVFLYHAIKAGMNMGIVNAGQLALYDDLPQEDVILNRHSGATEALEKYRGDG-TG----DKKEDERS-LPIAKR
IEHALVKGISTYIEADTEEARQHYPRPLDVIEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKQSVAYLQPYIEAEKEAKPNGKILMATVKGDVHDIGK
NIVGVVLQCNNFEVVDLGVMVPCDKILDTAISQNCDIIGLSGLITPSLDEMVFVAREMERRGINKPLLIGGATTSPVFH--LNQVVYVPDASRAVGIAST
LLS
>tr|K2PYW9|K2PYW9_9BURK Methionine synthase I, cobalamin-binding domain-containing protein OX=864073 OS=Herbaspirillum frisingense GSF30. GN=HFRIS_01660 PE=3 SV=1
---LRDLMSQ-RILILDGAMGTMIQRYKLTEGQNNELLSLTQPHIIQEIHEQYLAAGADLIETNTFGATSVAQDDHMLVYEMNLESARLARAACDKPRFV
AGALGPTPKTISPARNVTFDQLVTAYLEQTRALVEGGADVLLVETIFDTLNCKAALFAIDTFFRLPIMISGTVTSGRILSGQTVTAFWNSIRHARPLTVG
LNCALGAALMRPYAEELSRIADTYVCIYPNAGLPNP--MS--DFDETPDVTSALLKEFAESGVNVAGGCCGTTPPHIKAIAETVATIAPRKVPE--ATHE
MRLSGLEPFTINDESLYVNVGERTNVTGSKAFARLILNEQYDEALAVARQQVENGAQIIDINMDEAMLDSVAAMTRFLNLIASIARVPIMIDSSKWEVIE
AGLKCVQGKSIVNSISMKEEKFLREAKLCRRYGAAVIVMAFDEVGQADTFARKIEICERAYRLLDKLDFPPEDIIFDPNIFAVATGIEEAVDFIEATRWI
HENLYAKISGGVSNVSFSFPAREAIHTVFLYHAIKAGMTMGIVNAGMIGVYDDLPAEDVVLNRRDDATERMATLKAGD-KK----EEATLERS-EPVAKR
LSHALVHGITQWIVEDTEEVRQQIARPIHVIEGPLMDGMNVVGDLFGQGKMFLPQVVKSARVMKQAVAHLIPFIEEEKQGKPKGKIVIATVKGDVHDIGK
NIVTVVLQCNNFEVVNMGVMVPCAEILAKAKEEKADIIGLSGLITPSLEEMAYVAKEMQRDPYFMPLMIGGATTSPNY---EGPVVYVPDASRAVSVAQS
LLA
>tr|B2IJ02|B2IJ02_BEII9 Methionine synthase OX=395963 OS=8712). GN= PE=3 SV=1
---LLEAAAE-RVLVLDGAMGTMIQQRKFTEGENNDLLTLTQPDAIVAIHRAYFEAGADIIGTNTFNSTRISQADGMLVAELNRESARLARQAADERRFV
AGALGPTNRTISPFRAVTFDDLRAAYAEAASALIEGGADILIVETIFDTLNAKAALAAIDDVYRLPVMISGTITSGRTLSGQTPTAFWYSLRHVKPITIG
LNCALGAREMRAHIAELSRVADTLICAYPNAGLPNE--FG--LYDESPEYMASLVGEFAEAGVNIVGGCCGTTPAHIHAIAKRVAGIAPRKIPA--IEPL
LRLSGLEPFTLTKDIRFVNVGERTNVTGSAKFRKLIKEGQFSAALDVARDQVVMGAQVIDVNMDEGLLDSEAVMRDFLNLVAAIARVPVMIDSSKFVVIE
AGLKCIQGKGIVNSISLKEENFIQAAKAVHRYGAAVVVMAFDEQGQADTRARKVEICSRAYDILNRCGFPPEDIIFDPNIFAVATGIEEGVDFIEATREI
RQKFLVHISGGVSNLSFSFPVRQAMHSVFLYHAIAAGMDMGIVNAGQLSVYEELDPEDVVLNRRPEATERLENYKGQG-EK----QEKSLARE-EPVEKR
LEHALVNGITEFIDQDVEEARLASTRTLDVIEGPLMAGMNVVGDLFGSGKMFLPQVVKSARVMKAAVAYLMPFMEAEKNRSSAGKILMATVKGDVHDIGK
NIVGVVLACNNYEIIDLGVMVPAAKILETARAEQVDCIGLSGLITPSLDEMCFVAAELEREGFDVPLLIGGATTSPNYT--RGQTVYVTDASRAVGTVQS
LLS
>tr|A1S3K9|A1S3K9_SHEAM Methionine synthase (B12-dependent) OX=326297 OS=Shewanella amazonensis (strain ATCC BAA-1098 / SB2B). GN= PE=3 SV=1
---LNEDLST-RILILDGAMGTMIQGHKLEEGSNNDLLVLTQPEIIKGIHREYLLAGADIIETNTFNATTVAMADDMLSAEINLVGARIAREVADEPRYV
AGVLGPTNRTISPYRNIHFDDLVTAYRESTAALIEGGADIIMVETIFDTLNAKAALFAIESIFRLPVMISGTITSGRTLTGQTTEAFYNSLRHIKPISMG
LNCALGPKELRPYVEELSRISECYVSAHPNAGLPNE--FG--GYDETPKEMADIIVQWAIEGLNIVGGCCGTTPDHIRVIREAVEKHAPRKLPE--LPVA
CRLAGLEPLTISADSLFVNVGERTNVTGSAKFLKLIKEGQYETALDVARDQVENGAQIIDINMDEGMLDGEEVMTTFLNLVASISKVPIMIDSSKWEVIE
AGLKCVQGKCIVNSISLKEAKFIEQATLVKRYGAAAIIMAFDETGQADTRARKIEICTRAYRILDKVGFPPEDIIFDPNIFAVATGIEEAVDFIEAVRDI
KATLHAMISGGVSNVSFSFPVREAIHAVFLYHAIKEGMDMGIVNAGQLAIYDDIPAEAVVLNLPSTNTEQLEKYRGGGSAG----KKEDLQRS-LPVNKR
LEHALVKGITEFIDADTEEARQQATRPLDVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKKAVAYLNPFIEAEKAGQSNGKVLMVTVKGDVHDIGK
NIVGVVLACNGYEVIDLGVMVPVEKIVEVAKKEQVDIIGMSGLITPSLDEMVHNVKTFEREGLTLPAIIGGATCSPHY---PHGAIYIPDASRAVPMVSK
LIN
>tr|J1K055|J1K055_9RHIZ Methionine synthase OX=1094558 OS=Bartonella tamiae Th239. GN= PE=3 SV=1
---LQAAAQE-RILILDGAMGTQIQDLHYDEGHNNDLLTLTQPKAIEDIHFRYAIAGADILETNTFSSTSIAQADGMMVYELNRDGARLARRAAERPRFV
AGAIGPTNRTISPYRAVSFDDLRVAYGEQMRGLIDGGADLLLIETIFDTLNAKAAIFAAEEIFRLPIMISGTITSGRTLSGQTPTAFLYSVAHADPFSIG
LNCALGANAMLPLIKEMSEKTESFICVYPNAGLPNA--FG--EYDESADYMAAQIEHYARDGINIVGGCCGTTPDHIRAIAAKVKDYKPREISQ--IEKK
LRLSGLEPFTLSDDIPFVNVGERTNVTGSARFRKLITNNDYTAALDVARDQVENGAQIIDINMDEGLIDSQAVMHDYLNLLAAIARVPIMLDSSKWEVIE
AGLKCVQGKSVVNSISLKEENFIHQARLARAYGAAIVVMAFDEKGQADTKERKIEICTRAYAILEQVGFPPQDIIFDPNIFAVATGIDEGVDFIEATKEI
RETLFAHISGGVSNLSFSFPVREAMHSVFLYRAIAAGMDMGIVNAGQLAVYESIDPEDVVLNHDEGATERLEDYAGQT-RP----KEKDLTRT-WTVEKR
LEHALVNGITEYIDEDTEEARLQANRPLEVIEGPLMAGMNVVGDLFGAGKMFLPQVVKSARVMKQAVAILLPYMEEEKNRQSAGKIIMATVKGDVHDIGK
NIVGVVLACNNYEIVDLGVMVPAQKILDVAREEKADAIGLSGLITPSLDEMSNVAAEMQKQGFDIPLLIGGATTSPRYQ--RGQSVYVLDASRAVGVVSS
LLS
>tr|Q1QWB7|Q1QWB7_CHRSD Methionine synthase (B12-dependent) OX=290398 OS=13768). GN= PE=3 SV=1
---LQEQLSR-RIMILDGGMGTMLQGYELDEGQNNDLLVLTRPDVVRDIHRAYLEAGADIVETNTFNSTQLSQSDGMLVPELNREAARLAKDVCDAPRYV
AGVLGPTSRTLSPKRNVTFDQLCDNYYQAAEALLEGGADLIMIETIFDTLNAKAAIYALEMLFRLPVMISGTITSGRTLSGQTTEAFWNSIRHAQPLSVG
LNCALGAAELRPYLEELSHKADTYVSAHPNAGLPNE--FG--EYDQTAEEMATIVREFAESGVNIIGGCCGTAPEHIAAIRDAVGELPPRQVVE--RPKA
CRLAGLEPFNIEADSLFVNVGERTNVTGSARFKRLIKEEDYTTALEVALEQVENGAQVIDINMDEGMLESQDAMVRFLNLIASISRVPVMIDSSKWEIIE
AGLKCVQGKAVVNSISLKEDAFRQQATACRRYGAAIVVMAFDEEGQADTFQRKTEICERAYRLLDDIGFPAEDIIFDPNIFAIATGIEEAVDFIEASKWI
REHLHAMLSGGVSNVSFSFAVREAIHSVFLYHAIKAGLTMGIVNAGQLAVYDDLPEEDVVLNRRDDGTERLDKYKGDG-GG----EKKEDERS-WEVEKR
IEHALIKGITAYIEEDTEQARQRAARPIEVIEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKQAVAYLIPYIEAEKEGQAKGKIVMATVKGDVHDIGK
NIVGVVLQCNNYEVIDLGVMVPAEKIFAAAREHNADIIGLSGLITPSLDEMVHVAKEMQRQGFTLPLLIGGATTSPQY---DQPVIYVSDASRAVGVASR
LLS
>tr|Q0A6R3|Q0A6R3_ALHEH Methionine synthase (B12-dependent) OX=187272 OS=Alkalilimnicola ehrlichei (strain MLHE-1). GN= PE=3 SV=1
---LEDALAR-RILILDSGMGTMIQNRKLEEGENNDLLVLTRPEVIREIHAENLAVGADIVETNTFSSTTIAQADRMLAYEMNVAAARLAREACDAPRYV
AGALGPTNRTISPYRNITFDQLRAAYLEAARGLVEGGADLLLIETIFDTLNAKAAIYALEELFRLPVMISGTITSGRTLSGQTTEAFWNSVRHANPFTVG
LNCALGADQMRPFVKEISRVADTYVTIYPNAGLPNE--FG--EYDQTPEEMAAIVREFAESGVNVVGGCCGTTPEHIAALREAVADCVPRPIPE--RERA
MRLSGLEPFNVGKDSLFVNVGERTNVTGSARFRRLIKEEDYDTALEVAREQVENGAQIIDINMDEGMLDARACMVDFLNLIAAIARVPVMIDASKWEVLE
AGLQCLQGKAVVNSISLKEAPFLEQAEKLKRYGAAVVVMAFDEDGQADTYARRIEICERAYRLLDRAGFPPEDIIFDPNVFPVATGIPEGIDFIEATRWI
KANLYAKVSGGLSNLSFSFAVREAMHSAFLYHAIKAGLDMAIVNAGQIEVYDDIPKEDVILNRREDATERLESVKDQGAKK----KEADLARE-LPVNKR
LEHALVKGIVDYIDDDVEEARQAHDRPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKKAVAYLLPYIEAEKDDKPAAHILMATVKGDVHDIGK
NIVGVVLQCNNFKVTDIGVMQPAEAILETAEKEKVDIIGLSGLITPSLEEMANVAKEMQRRGLTQPLLIGGATTSPQY---DQEVIYVKDASRAVGVASN
LMS
>tr|B8ETT2|B8ETT2_METSB Methionine synthase OX=395965 OS=Methylocella silvestris (strain BL2 / DSM 15510 / NCIMB 13906). GN= PE=3 SV=1
---FLDAARK-RILVLDGAMGTMIQQHKFTEGENNDLLSLTQPKAIEQIHRAYIDAGADIIATNTFNSTSISQADGMLVFELNRESARLCRVAADARRFV
AGALGPTSRTISPFRAVSFDELRDAYDEAARALIEGGADLLIIETIFDTLNAKAALAGVRDAFEAPVMISGTITSGRTLSGQTPTAFWHSLRHADPLTIG
LNCALGAREMRAHLAELSRIADTLVCAYPNAGLPNE--FG--LYDESPEYMASLVGEFADSGVNVVGGCCGTTPAHIHAIAKRIEGVAPREIPE--IAPL
LRLSGLEPFVLAPEIPFVNVGERTNVTGSAKFRKLIKQGDFAAALDVARDQVAAGAQIIDVNMDEGLLDSEKAMVEFLNLIAAIARVPVMIDSSKFSVIE
AGLKCVQGKSVVNSISMKEEKFIADARTVRAYGAAVVVMAFDEKGQADTFERKVEICAKAYQILQEAGFPPEDIIFDPNIFAIATGIEEGVDFIEATREI
RKRFLVHISGGVSNLSFSFPVREAMHAVFLYHAIQAGMDMGIVNAGQLAVYAEIEPEDVVLNRRPDATERLEGFRGHG-EK----AERDLVRE-QPVIKR
LEHALVNGITEFVELDVEEARAASKRPLDVIEGPLMAGMNVVGDLFGAGKMFLPQVVKSARVMKQAVAYLLPYMDEEKNRSTAGKILMATVKGDVHDIGK
NIVGVVLACNNYEIIDLGVMVPAAKILSVARAEKVDAIGLSGLITPSLDEMCYVAAEMEREGFDLPLLIGGATTSPNYT--RGQTVYVNDASRAVGVVQS
LLG
>tr|A6VXB2|A6VXB2_MARMS Methionine synthase OX=400668 OS=Marinomonas sp. (strain MWYL1). GN= PE=3 SV=1
---IEKRLAE-NVLILDGAMGTMIQGYKLEEGENNDLLSLTQPKIIKDIYSSYLAAGADIIETNTFNANYISMLDHMLSYELNFESARLAREAADEPRFV
AGAVGPTSRTISPFRNVHFDELVDAYTTAVDGLIKGGVDIILIETIFDTLNAKAAIYAVLDYFRYPIMISGTITSGRTLSGQTTEAFWNSISHAKPISVG
LNCALGPKELRQYVEELSRIADTHVSAHPNAGLPNA--FG--EYDESPEEMLEEIQGWVDSGLNIIGGCCGTSPEHIATFAKAFADSTPRVIPE--IEKA
CRLSGLEPFNIDGNSLFVNVGERTNVTGSAMFKRLIKEGDFDTALDVARQQVENGAQIIDINMDEGMLDSQAAMERFLKLIASISRVPIMLDSSKWEILE
AGLKWIQGKGVVNSISMKEDKFREQARKLMKYGAAVIVMAFDEVGQADTRARKIEICRRSYHILDEVGFPPEDIIFDPNIFAIATGIEEALDFIEATGDI
TRELYAKVSGGVSNVSFSFPVREAIHAVFLYHAIKQGMTMGIVNAGQLALYEDIPTEDAVLNRTPDATDNLGEFAGTGEVA----EKETQERG-LPVSER
LSHALVKGITEFIDEDTEEARQAFARPLEVIEGPLMDGMGIVGDLFGSGKMFLPQVVKSARVMKKAVAYLMPFIEEEKASSSNGKIVMATVKGDVHDIGK
NIVGVVLQCNNFEVIDLGVMVPAEKILRTAKEEGADMIGLSGLITPSLDEMVHVAKEMERQGFDLPVMIGGATTSQNY---KRNVVHVTNASRSVGVASA
LLS
>tr|A3Y840|A3Y840_9GAMM B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase,repressor of metE and metF OX=314277 OS=Marinomonas sp. MED121. GN=MED121_12105 PE=3 SV=1
---IEERLAQ-NILVLDGAMGTMIQAYKLTEGDNNDLLSLTQAKIIKDIHKAYLAAGSDIVETNTFNANAISMLDGMLSYELNFESARLAREACDEPRFV
AGAVGPTSRTISPYRNIEFDELVVAYTEAVDGLIKGGSDLILIETIFDTLNAKAAIYAVLEYFRYPVMISGTITSGRTLSGQTTEAFWNSVSHANPISVG
LNCALGPKDLRQYVEEISRVADVNVSAHPNAGLPNA--FG--EYDETPEEMLEEMQEWVNSGLNIIGGCCGTEPSHIKAFADAVANAKPRAIPE--IPKA
CRLSGLEPFNIDENTLFVNVGERTNVTGSAIFKRLIKEGDFDSALTVARQQVENGAQIIDINMDEGMLDSEAAMVRFLKLIASISRVPIMLDSSKWEILE
AGLKCIQGKGVVNSISMKEENFTEQARKLRKYGAAVIVMAFDEVGQADTRERKIEICRRSYQILEEVGFPPEDIIFDPNIFAIATGIEEALDFIEATGDI
KRELHALISGGVSNVSFSFPVREAIHAVFLYHAIQQGMTMGIVNAGQLALYDDIPAEDAVLNRTDNATDTLTEFLGTGNDN----EVQVQERS-LAVNER
LSHALVKGITEFIDEDTEEARLAHTRPLEVIEGPLMDGMGIVGDLFGSGKMFLPQVVKSARVMKKAVAYLMPFIEEEKASSSNGKIVMATVKGDVHDIGK
NIVGVVLQCNNYEVIDLGVMVPAEKILRTAREENANLIGLSGLITPSLDEMVHVAKEMERQEFDIPVLIGGATTSQGY---KRSVVHVTNASRSVGVASN
LLS
>tr|Q8EI23|Q8EI23_SHEON B12-dependent 5-methyltetrahydrofolate--homocysteine methyltransferase MetH OX=211586 OS=Shewanella oneidensis (strain MR-1). GN= PE=3 SV=1
---IRNQLST-RILILDGAMGTMIQGYKLEEGENNDLLVLTQPHIIKQIHTDYLLAGADIIETNTFNATTIAMADDMLSAEINREGARLAREACDAPRYV
AGVLGPTNRTISPFRNIHFDELVTAYCESTRALIEGGADIIMVETIFDTLNAKAALFAIETVFRLPVMISGTITSGRTLTGQTTEAFYNSLRHIKPLSIG
LNCALGPKELRPYVEELSRIAECYVSAHPNAGLPNE--FG--GYDETPEDMAKVIQEWAREGLNIIGGCCGSTPEHIKVIREAVEQFAPRVLPE--IPVA
CRLAGLEPLTIDAQTLFVNVGERTNVTGSAKFLKLIKEGKFEQALDVAREQVESGAQIIDINMDEGMLDGVEIMHKFLNLIASISRVPIMIDSSKWEVIE
AGLKCIQGKGIVNSISLKEEKFIEQATLVKRYGAAAIIMAFDEQGQADTKARKVEICTRAYRVLDKVGFPPEDIIFDPNIFAIATGIDEAVDFIDAIKEI
KATLHAMISGGVSNVSFSFPVREAIHAVFLYHAIKVGMDMGIVNAGQLAIFDDIDPENVVLNLPSNNTEQLEKFRGDGSSA----KKEDLERS-WPVNQR
LAHALVKGITEFIDEDTEAARQAASRPLDVIEGPLMDGMNIVGDLFGSGKMFLPQVVKSARVMKKAVAYLNPFIEKEKAGQSNGKILMVTVKSDVHDIGK
NIVGVVLACNGFEVFDLGVMVSVERILEAVKEHNIDIIGMSGLITPSLDEMVHNVKTFHREGLTIPAIIGGATCSPHY---PHGAIYIADASRAVPMVSK
LVN
>tr|F2K2Q2|F2K2Q2_MARM1 Methionine synthase OX=717774 OS=/ MMB-1). GN= PE=3 SV=1
---IENRLKE-NILILDGAMGTMIQDYKFEEGENNDLLSLTQPQVIKAIHTAYLEAGADIVETNTFNANAISMLDHMLSYEINYESAKLARQAADEPRFV
AGAIGPTSRTISPYRNVHFDELVAAYDTALDGLIKGGVDLILIETIFDTLNAKAAIYAALEYFRYPIMISGTITSGRTLSGQTTEAFWNSIAHAKPISVG
LNCALGPKDLRQYIDELSRIADTQVSAHPNAGLPNA--FG--EYDESPEEMLEEIQGWVDSGLNIIGGCCGTTPEHIAVFAEAFKESAPRTIPE--IEKA
CRLSGLEPFNIDESSLFVNVGERTNVTGSARFKRLIKEGDYDAALEVARQQVENGAQIIDINMDEGMLDSQAAMERFLKLIASISRVPIMLDSSKWEILE
AGLKWVQGKGVVNSISLKEEKFVEQARKLMKYGAAVIVMAFDEVGQADTRERKIEICRRSYDVLNKVGFSPEDIIFDPNIFAIATGIEEALDFIEATGDI
KRELYAKISGGVSNVSFSFPVREAIHAVFLYHAIKQGMTMGIVNAGQLAVYEDIPPEDAVLNRTPDATDTLGEFVGTGETV----EAETQERS-FDVSER
LSHALVKGITEFIDEDTEEARQQYDRPLEVIEGPLMAGMSIVGDLFGAGKMFLPQVVKSARVMKKAVAYLMPFIEEEKASSSAGKVIMATVKGDVHDIGK
NIVGVVLQCNNFEVIDLGVMVPAEKILRTAREENADIIGLSGLITPSLDEMVHVAKEMERQEFDLPVMIGGATTSQNY---KRNVVHVTNASRSVSVASS
LLT
>tr|D7A2F2|D7A2F2_STAND Methionine synthase OX=639283 OS=NBRC 12443 / NCIB 9113). GN= PE=3 SV=1
---LRAAASE-RILVLDGAMGTMIQQLKLDEGENNDLLNLTKPDAVRDIHLAYFTAGADIVETNTFSGTTIAMADGMLVYEINFEGARLAKEAAKLRRFV
AGAIGPTNRTISPFRATSFDELATAYGEQAAALIDGGSDLLLIETIFDTLNAKAAIFAIERLFRLPVMISGTITSGRTLSGQTPEAFWNSVRHAQPFSIG
LNCALGAKEMRAHIDELSRISDTFVCAYPNAGLPNE--FG--LYDESPAAMAKLVGEFAASGVNVVGGCCGTTPDHIRAIAEAVAPHAPREIPE--IEPR
LRLSGLEPFELTPNIPFVNVGERTNVTGSARFRKLITNGDYTAALAVARDQVENGAQVIDVNMDEGLLDSEKAMVTFLNLLAAIARVPIMVDSSKWSVIE
AGLKCIQGKGIVNSISMKEEAFKHHARLVRAYGAAVVVMAFDEKGQADTYERKVEICARAYRILEEVGFPPEDIIFDPNIFAVATGIEEGVAFIEATRAI
RQQLHAHISGGVSNLSFSFPVREAMHAVFLYHAIAAGMDMGIVNAGQLAPYSEIEPEDVVLNRRDDSTERLERFKGGG-EK----KEADLTRT-WTVEKR
LEHALINGITDYVEADTEEARQAAARPLHVIEGPLMAGMNVVGDLFGAGKMFLPQVVKSARVMKQAVAYLMPFMEIEKLAASAGKILMATVKGDVHDIGK
NIVGVVLQCNNYEVIDLGVMVPTAKILEVAKTEKVDVIGLSGLITPSLDEMVHVASEMEREGFDLPLLIGGATTSPQYV--RGQAVYVTDASRAVGVVSS
LLN
>tr|H5TCE4|H5TCE4_9ALTE 5-methyltetrahydrofolate--homocysteine methyltransferase OX=1121923 OS=Glaciecola punicea DSM 14233 = ACAM 611. GN= PE=3 SV=1
---LEQQLAK-RILLLDGAMGTMIQAYDFSEGENNDLLVLSQPHIISTIHREYLAAGADILETNTFNATRIAMADEMLSREINVQAAKIARKVADEPRFV
AGVLGPTNRTISPFRNVTFDELKDAYIESILALLEGGADIIMIETIFDTLNAKAAVFAVEQVFRYPVMISGTITSGRTLSGQTTEAFYNSLAHAKPISFG
LNCALGPKELRQYVEELSRISSCAVSAHPNAGLPNA--FG--GYDLDAQEMNEHIKEWAQSGLNIVGGCCGTTPEHIRVMAEVLANIPPRIIKD--IKVA
CRLSGLEALTIDAKSLFVNVGERTNVTGSALFKKLIVEELYDDALSVALQQVENGAQIIDINMDEGMLDSKTAMQRFLNMIAGIAKVPIMIDSSKWDILE
AGLKCVQGKGIVNSISLKEDNFREQAELIRRYGAAVIVMAFDEVGQADTRVRKFQICQRAYNILDELNFPPQDIIFDPNIFAVATGIEEAVDFIEAVADI
KKNLHAMISGGVSNVSFSFAVREAIHAVFLYYAIKNGMDMGIVNAGQLAILKDVPAEHVVQNSDDGATERLAKYSSTGAKS----SVLDLSRE-LSTHKR
LEHALVKGINAFIIEDTEAARLEAKIPLHVIEGPLMDGMNIVGDLFGEGQMFLPQVVKSARVMKQAVAHLQPFIEEGKEITDNGKVLMATVKGDVHDIGK
NIVGVVLQCNNFAITDLGVMVACEKILTTARELKVDVIGLSGLITPSLDEMVHIAKEMQRQGFTIPLLIGGATTSPHY---KHGVVYVPNASRSVSVVQT
LLN
>tr|J3D2Z7|J3D2Z7_9ENTR 5-methyltetrahydrofolate--homocysteine methyltransferase OX=1144320 OS=Pantoea sp. GM01. GN=PMI17_04090 PE=3 SV=1
---LQQQLAQ-RIMILDGGMGTMIQSYKLSEGSNNDLLVLTRPDVIREIHDAYLAAGADILETNTFNSTTIAMADAMLSAEINFEAAKLARASADAPRYV
AGVLGPTNRTISPYRNVTFNQLVEAYRESTHALIAGGSDLIMIETVFDTLNAKAAIYAVQAEMKLPLMISGTITSGRTLSGQTTEGFYNSLRHAEPLSFG
LNCALGPDELRQYVAELSRIAEGYVTAHPNAGLPNA--FG--EYDLDAAIMAEQIGEWARAGLNIIGGCCGTTPEHIAAMAAAVEGVAPRQLPE--IPVA
CRLAGLEPLNIHADSLFVNVGERTNVTGSAKFKRLIKEEKYNEALDVARQQVESGAQIIDINMDEGMLDAEAAMVRFLNLIAGIARVPIMIDSSKWEVIE
KGLQCIQGKGIVNSISMKEEPFIEHARKVRRYGAAMVVMAFDEVGQADTRARKIEICRRAYKILEEVGFPPEDIIFDPNIFAVATGIEEAMDFIGACADI
KRELHAMISGGVSNVSFSFPVREAIHAVFLYYAIRNGMDMGIVNAGQLAIYDDLPAEDVVLNRRDDGTERLEKYRGS-KSD----GEQQAERS-WDVVKR
LEYSLVKGITEFIELDTEEARQASERPIQVIEGPLMSGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAYLEPYIQASKAGRSNGKIVLATVKGDVHDIGK
NIVGVVLQCNNYEIIDLGVMVPSDKILKTAIAENADIIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSQNY---SGPTVYVQNASRTVGVVSS
LLS
>tr|E2XR39|E2XR39_PSEFL 5-methyltetrahydrofolate--homocysteine methyltransferase OX=746360 OS=Pseudomonas fluorescens WH6. GN= PE=3 SV=1
---LHHALKD-RILILDGGMGTMIQSYKLEEGKNNDLLVLTRPDVIGGIEKAYLDAGADILETNTFNATRISMADGMLAYELNVEGARLARKIADAPRFV
AGVLGPTSRTLSPYRNVTFDELVENYTEATQGLIEGGADLILIETIFDTLNAKAAIFAVQGVFELPIMISGTITSGRTLSGQTTEAFWNSVAHAKPISVG
LNCALGASELRPYLEELSNKANTHVSAHPNAGLPNE--FG--EYDELPSETAKVIEEFAQSGLNIVGGCCGTTPGHIEAIAKAVAGYAPRPIPD--IPKA
CRLSGLEPFTIDRSSLFVNVGERTNITGSARFARLIREDNYTEALEVALQQVEAGAQVIDINMDEGMLDSKKAMVTFLNLIAGISRVPIMIDSSKWEVIE
AGLKCIQGKGIVNSISMKEEQFIHHARLCKRYGAAVVVMAFDEAGQADTEARKKEICKRSYDILNEVGFPPEDIIFDPNIFAVATGIEEAVDFINACAYI
RDELYALTSGGVSNVSFSFPVREAIHSVFLLYAIRNGLTMGIVNAGQLEIYDQIPAEDVVLNRTPDGTDALDKYKGEG-VK----EAETEERG-WPVNKR
LEHALVKGITTHIVEDTEESRLSFARPIEVIEGPLMSGMNIVGDLFGAGKMFLPQVVKSARVMKQAVAHLIPFIELEKDKEAKGKILMATVKGDVHDIGK
NIVGVVLGCNGYDIVDLGVMVPAEKILQVAREQKCDIIGLSGLITPSLDEMVHVAREMQRQDFHLPLMIGGATTSPKYS--NDAVIYVTDASRAVGVATQ
LLS
>tr|D5QST0|D5QST0_METTR Methionine synthase OX=595536 OS=Methylosinus trichosporium OB3b. GN=MettrDRAFT_2856 PE=3 SV=1
---LEQAASE-RILVLDGAMGTMIQRHKFTEGENNDLLTLTQPDAIEAIHRAYLEAGADIIETNTFSCTAIAQADGLIVYELNLEGARLARKAADAPRFV
AGSMGPTNRTISPFRAVTFEDLRAAYHEEALGLIEGGADILLIETIFDTLNAKAAIYAVEDAFRFPVMISGTITSGRTLSGQTAAAFWNSIQHAKPFSIG
FNCALGAREMRQHIAEVSRIADTRICAFPNAGLPNE--FG--LYDESPEYMAELVGEFAKSGVNVVGGCCGTTPPHIAAIAGAVKGVAPRAIPE--IEPL
LRLSGLEPFTLTKDIPFVNVGERTNVTGSAKFRKLITNGDYAAALDVARDQVANGAQVIDINMDEGLLDSKKAMVEFLNLLAAIARVPVMVDSSKFEVIE
AGLQCLQGKGVVNSISLKEEKFIEAATKVKRYGAAVVVMAFDEAGQADTFARKVEISGRAYKILEEVGFPPQDIIFDPNIFAVATGIEEGVDFIDAARAI
KTTLHAHVSGGVSNLSFSFPVREAMHSVFLYHAIAAGMDMGIVNAGQLAVYEKIDPEDVVRNRRPDATERLERFKGAG-KS----AEKDAARE-ASVEKR
LEYALVNGVADYVDQDVEEARLASARPLDVIEGPLMAGMNVVGDLFGQGKMFLPQVVKSARVMKQAVARLLPYMEENK-RSSAGKILLATVKGDVHDIGK
NIVGVVLGCNNFEIIDLGVMVPTAKILETAKAEKVDIIGLSGLITPSLDEMCFVASELEREGFSAPLLIGGATTSPNYS--KGQAVYVTDASRAVGVAQA
LMS
>tr|G2IUE6|G2IUE6_PSEUL B12-dependent methionine synthase OX=748280 OS=Pseudogulbenkiania sp. (strain NH8B). GN= PE=3 SV=1
---LYDHLSR-RILILDGGMGTMIQRHQLTEGENNDLLVLTQPGIIGGIHQAYLDAGADIVETNTFNATSIAMADEMLVWEINHAAARLVKELCVAPRYC
AGVLGPTNRTISPYRNVTFDALVESYTEAIDGLVKGGADLLLVETIFDTLNAKAAVFAIHKYFRLPIMVSGTITSGRTLTGQTTEAFYNSLSHADAISFG
LNCALGPDLLRPYVEEMARISSTFVSVHANAGLPNA--FG--GYDLSPADMAVNVREWAESGINIVGGCCGTTPEHIAAICLAVQDLPPRALPA--LEPK
CRLSGLEPFNIGDADLFVNVGERTNVTGSKAFARLILNGDYATALDVARQQVENGAQIIDINMDEGMLDAHAAMVRFLNLIAAIARVPIMIDSSKWEVIE
AGLKCIQGKGIVNSISMKEDKFVEQARLIRHYGAAVIVMAFDEAGQADTYARKVEICEKSYRILDEVGFPPEDIIFDPNIFAVATGIEEGLDFIEATGWI
KQNLHAKISGGVSNVSFSFKVREAIHAVFLYHAIKRGMTMGIVNAGALEVYDEVDPEDVVLMQDDSMAEALESFRGDA-EA----KGEDLARS-QPVEKR
LEHALIKGITTYIVEDTEEVRLKCERPIHVIEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKAAVAHLEPFIEEEKMGPAKGVIIMATVKGDVHDIGK
NIVGVVLRCNNYKVIDLGVMVPCQKILDAAIEHKADIIGLSGLITPSLEEMSHVAKEMQRQGFTIPLLIGGATTSPNY---HGPVIYVPDASRAVGVCSN
LLS
>tr|F9Y766|F9Y766_KETVW Dihydropteroate synthase, DHPS:Homocysteine S-methyltransferase:Cobalamin-dependent methionine OX=759362 OS=Ketogulonicigenium vulgare (strain WSH-001). GN= PE=3 SV=1
---IVDAARQ-RILVLDGAMGTQIQLLKMGEGHNNDLLNLTQPEAIEEIHFRYAMAGADIVETNTFSSTTIAQADALQVHALNVQGARLARSGVDRMRFV
AGAVGPTNRTISPFRAVSFDDLRIAYAQQIRGLIEGGVDLILIETIFDTLNAKAAIFAAEEVFRLPVMISGTITSGRTLSGQTPTAFWHSVRHAGPFTIG
LNCALGANAMRAHLAEISAIADTFVCVYPNAGLPNA--MG--DYDETPAFTAQQIEGFARDGVNIVGGCCGTSPEHIRAMAEAVAKYRPRAIPE--HAPL
MRLSGLEPFILTPEIPFVNVGERTNVTGSAKFRKMITAGDFASALQVARDQVENGAQIIDINMDEGLIDSQAAMVKFLNLVASIARVPVMIDSSKWDVIE
AGLKCVQGKAIVNSISMKEAAFLHHARLCRAYGAAVVVMAFDETGQADTEDRKVEICSRAYKLLEEVGFPPEDIIFDPNVFAVATGIEEGVDFINATRRI
MEACHVHISGGISNLSFSFPVREAMHAVFLYHAIQVGMDMGIVNAGQLAVYDQIDPEDVVLNRRDDATERLERYRGQG-EK----KERDLARD-WDVAKR
LEHALVNGITEFIEGDTEEARLAAQRPLHVIEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKQAVAVLLPYLEEEKGRQSAGKILMATVKGDVHDIGK
NIVGVVLACNNYDIIDLGVMVSSEKILAAAREHDVDAIGLSGLITPSLDEMVHVAAEMERQGFDIPLLIGGATTSPAYQ--RGQVVYSVDASRAVGVAQN
LLG
>tr|F2J1F3|F2J1F3_POLGS Probable 5-methyltetrahydrofolate--homocysteine methyltransferase (Methionine synthase, vitamin-B12 dependent isozyme) protein OX=991905 OS=Polymorphum gilvum (strain LMG 25793 / CGMCC 1.9160 / SL003B-26A1). GN= PE=3 SV=1
---LKAVADE-RILILDGAMGTEIQALRLDEGANNDLLNLTRGEAIRDIHLAYYRAGAHIVATNTFSSTTIAQADGMLAYELNLEGARLACAARDRPAFV
AGALGPTNRTISPYRAVSFDDLRQAYGEAARGLIEGGADILLVETIFDTLNAKAALFAIDEVFRLPVMISGTITSGRTLSGQTPEAFWNSLRHAEPFTIG
LNCALGAKEMRAHIAELARVADTLVCAYPNAGLPNE--FG--DYDESPEHMAGLLGEFARAGVNVVGGCCGTTPAHIRAIAEAVAPHRPRALPD--VPRH
MRLSGLEPFVVTPQTNFVNVGERTNVTGSARFRKLVKEGDYTAALDVARSQVENGAQIIDVNMDEGLLDSEAAMVTFLNLVAAIARVPVMIDSSKWSVIE
AGLKCIQGKGVVNSISMKEAAFVAQARLVRRYGAAVVVMAFDEQGQADTFARKTEICARSYKLLEQVGFPPEDIIFDPNIFAVATGIEEGVDFIEATGWI
RETLHAHVSGGVSNLSFSFSVREAMHSVFLYHAIARGMDMGIVNAGQLAIYDDLDPEDVVLNRRKDATDRLERWKGEG-RK----KEADLARG-WPVARR
LEHALVNGITDFIEEDTEEARRSFERPLHVIEGPLMDGMNVVGDLFGSGKMFLPQVVKSARVMKKAVAYLMPFMEAEKLQSSAGRILMATVKGDVHDIGK
NIVGVVLQCNNFEVIDLGVMVPAARILETARAEKVDIIGLSGLITPSLDEMCHVAAELEREGLDVPLLIGGATTSPNYA--RGQAIYVTDAGRAVGVCSR
LMS
>tr|K2GVK2|K2GVK2_9GAMM B12-dependent methionine synthase OX=391936 OS=Alcanivorax sp. W11-5. GN= PE=3 SV=1
---LEEQFRR-RILILDGGMGTMIQARRFDEGENNDLLCLTQPDAILDIHREYLAAGADILETNSFNATRIAMADDMIAREINVASARLARQAADEPRFV
AGVLGPTNRTISPFRNVSFDQLVEAYLESIDGLIEGGAQLLLIETVFDTLNAKAAVFAVETWKDVPVMISGTITSGRTLTGQTTEAFYNSLRHARPITIG
LNCALGAQELRPYMSELSRISEGYVSAHPNAGLPNE--MG--EYDQSPDVMAKEIRDWAQKGLNLIGGCCGTTPAHIRAIAEAVADCTPRALPD--VAPA
CRLAGLEPLNITEDSLFINIGERTNVTGSKRFLRLIKEGDYDTALEVARQQVEAGAQMIDINMDEGMLESVDAMVRFLNLVAAIAKVPIMIDSSKWEVIE
AGLKCIQGKGIVNSISMKEEKFIEQARLVRRYGAAVIVMAFDEVGQADTRERKTEICTRAYRLLDKVGFPAEDIIFDPNIFAIATGIEEAVDFIEAVHDI
KTTLHAQVSGGVSNVSFSFPVREAIHAVFLYHAIRAGMDMGIVNAGQLAIYEDIPAEDVVLNRREDGTDILEKYRDSAGGG----RQEDLSRE-WPVKQR
LQHALVKGVADYIEEDTEAARLESVRPLHVIEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKKAVAYLLPFMEKERQDESNGRIIMATVKGDVHDIGK
NIVGVVLQCNGYEVIDLGVMVPCEKILDAAREHKADIIGLSGLITPSLDEMVQVASEMERLGFELPLMIGGATTSPQY---HGPVIHVADASRAVGVASQ
LLS
>tr|E2CKI5|E2CKI5_9RHOB Methionine synthase OX=744980 OS=Roseibium sp. TrichSKD4. GN= PE=3 SV=1
---IQEAAQS-RILVLDGAMGTELQLLKLKEGDNNDILSLSQPDAIRKIHVDYLEAGADIVETNTFSSTTIAQADGMLAFELNVESAKLARQACDIPRFV
AGALGPTNRTISPYRAVSFDDLRIAYAEAVRGLLEGGADILLVETIFDTLNAKAALFAIDEVFAVPVMISGTITSGRTLSGQTPEAFWNSVRHSNPLTIG
LNCALGAKEMRAHLAEISRVADTLVCAYPNAGLPNE--FG--EYDESPEYMASLIEEFAEAGVNVVGGCCGSTPAHIRAIAEAVKDKAPRKIAE--PPVH
MRLSGLEPFTLTPEVNFVNVGERTNVTGSARFRKLIKTGDYTTALDVARDQVENGAQIIDVNMDEGLLDSEEAMVTFLNLMAAISKVPVMVDSSKWSVIE
AGLKCLQGKGVVNSISLKEENFIEQANLIRRYGAAVVIMAFDEQGQADTFERKIEICKRSYDVLEKVGFPPEDIIFDPNIFAVATGIEEGVDFIEATGWI
RENLHAHVSGGVSNLSFSFGVREAMHSVFLYHAIKKGMDMGIVNAGQLAVYDKLDKEDVVLNRTPDATDNMERWKGEG-KK----REVDLSRE-LPVAKR
LEHALVNGIDEYVVEDTEEARTQFDRPLHVIEGPLMDGMNVVGDLFGSGQMFLPQVVKSARVMKKAVAYLMPFMEKEKQASSNGKILMATVKGDVHDIGK
NIVGVVLQCNNFEVIDLGVMVPAAKILEVAKEEKVDIIGLSGLITPSLDEMCHVAGELEREGLDVPLLIGGATTSPNYA--RGQAIYVTDAGRAVGVASR
LMS
>tr|A0P2G4|A0P2G4_9RHOB Methionine synthase OX=384765 OS=Labrenzia aggregata IAM 12614. GN=SIAM614_17489 PE=3 SV=1
---LRDLAKT-RILVLDGAMGTEIQLLKLDEGDNNDLLSLTQPDAIRKIHVDYLEAGADIVETNTFSSTTIAQADGMLAYELNFESAKLAREACDKPRFV
AGALGPTNRTISPYRAVSFDDLRIAYAEATRGLIAGGADIILVETIFDTLNAKAALFAVDEVFILPVMISGTITSGRTLSGQTPEAFWNSVRHTNPLTIG
LNCALGAKEMRAHVDELGRVADTLVCAYPNAGLPNE--FG--EYDESPEHMAGLIEEFASAGVNVVGGCCGTTPAHIKAIAEAVSDKKPREIPE--IDVH
MRLSGLEPFVVTKETNFVNVGERTNVTGSARFRKLIKEGDYPTALEVARQQVENGAQIIDINMDEGLLDSEEAMVTFLNLVAAIAKVPIMIDSSKWTVIE
AGLKCIQGKGVVNSISMKEEAFIEQAKKVRRYGAAVVVMAFDEKGQADTFERKTEICARSYKILEKVGFPPEDIIFDPNIFAVATGIEEGVDFIEATGWI
RENLHAHVSGGVSNLSFSFAVREAMHSVFLYHAIKRGMDMGIVNAGQLAVYNDLETEDVVLNRRKDSTDRMERWKGEG-KK----READLTRT-LGVAKR
LEHALVHGIADYVEEDTEEARQAFDRPLHVIEGPLMDGMNVVGDLFGSGQMFLPQVVKSARVMKKAVAYLMPFMEKEKLHSSAGKILMATVKGDVHDIGK
NIVGVVLQCNNFEVIDLGVMVPAAKILDTARQEKVDMIGLSGLITPSLDEMCHVAAELEREGLDVPLLIGGATTSPNYA--RGQAIYVTDAGRAVGVASK
LMS
>tr|Q12Q73|Q12Q73_SHEDO Methionine synthase (B12-dependent) OX=318161 OS=Shewanella denitrificans (strain OS217 / ATCC BAA-1090 / DSM 15013). GN= PE=3 SV=1
---LTELLAQ-RIVMLDGAMGTMIQDYKLEEGQNNDLLVLSQPQIIKQIHLDYLLAGSDIIETNTFNATTIAMADDMLAAEINQVGARLAREAADERRYV
AGVLGPTNRTISPFRNVSFDQLVKAYLESSLALIQGGADIIMVETIFDTLNAKAALFAIEKAFRLPVMVSGTITSGRTLTGQTTEAFYNSLRHIKPISIG
LNCALGPKELRPYVEELARISETYISVHPNAGLPNE--FG--GYDETPAEMAEILAQWAEEGVNIVGGCCGSTPAHIRAIAEAVDKFDARALPD--IAIA
CRLSGLEPLTIDSNSLFVNVGERANVTGSAKFLRLIKEEKFEEALDVVREQVENGAQIIDVNMDEGMLDGVAAMSQFLNLIASISRVPIMIDSSKWEVIE
AGLKCVQGKAIVNSISMKEAAFIKQATLVKRYGAAAIVMAFDEDGQADTRKRKTEICTRAYRLLDVVGFPPEDIIFDPNIFAIATGIDEAVDFIESIKDI
KANLHAMISGGVSNVSFSFPVREAIHAVFLYHAIQAGMDMGIVNAGQLAIYDDIDPENVVRNLPSSNTEQLEQFRGDGQEV----KKEDSARS-LPVAER
LSYALVKGITEFIDEDTEAARLESVRPLDVIEGPLMNGMNVVGDLFGSGKMFLPQVVKSARVMKKAVAYLNPYIELEKEGQSNGKILMVTVKGDVHDIGK
NIVGVVLACNGYEVIDLGVMVSIEKIIEVARAEKVDIIGMSGLITPSLDEMVHNVKTLIREGLSLPVIIGGATCSPHY---PPGAIYIADASRAVPMVAK
LIG
>tr|A3QAT4|A3QAT4_SHELP Methionine synthase (B12-dependent) OX=323850 OS=Shewanella loihica (strain ATCC BAA-1088 / PV-4). GN= PE=3 SV=1
---LNKE-----ILILDGAMGTMIQNHKLEEGENNDLLVLTQPELIKQIHRDYLLAGADIIETNTFNATQVAMADEMLSREINLEGARLARTACDEQCYV
AGVLGPTNRTISPYRNIHFDDLVEAYIESTQALIEGGADIIMVETIFDTLNAKAALFAIETLFRLPVMISGTITSGRTLTGQTTEAFYNSLRHVKPLSIG
LNCALGPQELRPYVEELSKIAECYVSAHPNAGLPNE--FG--GYDETPEQMAEVIGPWAEEGLNIIGGCCGTTPDHIKAIRAAVIKHGARELPD--LPVA
CRLSGLEPLTIDADSLFVNVGERTNVTGSAKFLRLIKTGEYEEALSVARDQVENGAQIIDINMDEGMLDGVEVMQKFLNLIASISRVPIMIDSSKWEVIE
AGLKCIQGKGVVNSISLKEAKFIEQATLVKRYGAAAIIMAFDEVGQADTMARKIEICTRAYRVLDKVGFPPEDIIFDPNIFAIATGIDEAVDFIEATREI
KRTLHAMISGGVSNVSFSFPVREAIHAVFLYHAIQAGMDMGIVNAGQLAIYDDIDPEAVVQNLPSNNTEQLEQYRGDGAGA----KKEDLERS-WPVNKR
LEHALVKGITEFIDQDTEEARQLASRPLDVIEGPLMDGMNVVGDLFGSGKMFLPQVVKSARVMKKAVAYLNPYIEAEKEGESNGKILMVTVKGDVHDIGK
NIVGVVLACNGYEVVDLGVMVPVEKIIEVAKAEKVDIIGMSGLITPSLDEMVHNVKAFHKAGLNIPSIIGGATCSPHA---PEGAIYIADASRAVPMVAK
LIN
>tr|E8KXZ5|E8KXZ5_9RHIZ Methionine synthase OX=622637 OS=Methylocystis sp. ATCC 49242. GN=Met49242DRAFT_0229 PE=3 SV=1
---LEEAASS-RILILDGAMGTMIQRHKFEEGENNDLLILTQPEAIKAIHIQYLEAGADIIETNTFSSTTIAQADGLLAFELNREGAKLARAAADERRFV
AGSMGPTNRTISPFRAVTFDELRAAYREAALGLIDGGADIMLVETIFDTLNAKAAIYALEDAFRFPIMISGTITSGRTLSGQTSVAFWNSLAHAKPFSIG
FNCALGAREMRQHIAEIGRIADTRVCAFPNAGLPNE--FG--LYDESPEYMAELVGEFASAGVNILGGCCGTTPDHIGAIAQKVKGMKPRVVPK--IEPM
LRLSGLEPFALTKDIPFVNVGERTNVTGSAKFRKLITNGDYTAALDVARDQVANGAQVIDVNMDEGLLDSQQAMIDFLNLLAAIARVPVMVDSSKFEVIE
AGLKCLQGKGVVNSISLKEEKFIQEAQKVRRYGAAVVVMAFDETGQADTLARKTEICARAYKILEQVGFPPQDIIFDPNIFAVATGIEEGVDFIEAARVI
KRELYAHVSGGVSNLSFSFPVREAMHSVFLYHAIQAGMDMGIVNAGQLAVYAEIDPEDVVLNRRKDATERLEKFKGGG-KT----QEKDAARE-HSVEKR
LEYALVNGVTDYIEADVEEARQRSSRPLDVIEGPLMDGMNVVGDLFGQGKMFLPQVVKSARVMKQAVAYLMPFMEADK-RSTAGKILLATVKGDVHDIGK
NIVGVVLGCNNFEVIDLGVMTPAAKILETAKKEKVDLIGLSGLITPSLDEMCFVAAELEREGLDMPLLIGGATTSPNYR--RGQAVYVTDASRAVGVAQA
LVS
>tr|Q31JA5|Q31JA5_THICR Methionine synthase (B12-dependent) OX=317025 OS=Thiomicrospira crunogena (strain XCL-2). GN= PE=3 SV=1
---LRSLLNQ-RIVVLDGAMGTMVQDLALSEGDNNDILVMTQPAMIRDIHLAFLRQGADIIETNSFNATTIAQADDMTVTELNIAAATVAREACQIPRFV
AGVLGPTNRTISPKRNTHFDELVTAYKQATHALLKGGADVILIETIFDTLNAKAAIFAVKDVEEVPIMLSGTITSGRTLSGQTTEAFYNAVAHAQPLSIG
LNCALGPEELRQYVEELSRVCETYVSVHPNAGLPNE--FG--EYDETPEQMAHEIAIWAEKGLNIIGGCCGTTPDHVEAMANAALAHPARTLPE--IAPA
CRLSGLEPLNIDDNSLFVNIGERNNVTGSAKFKRLIIEENYNEAIDIAVKQVEDGAQIIDVNMDEGMLDAKACMVKFLNLLASASRVPIMIDSSKWEVIE
AGLKCIQGKGVVNSISLKEDAFIQQARLVKKYGAAAIVMAFDEDGQADTLERKIEICERSYNVLQKVGFLPQDIIFDPNIFAVATGIEEGLDFINAVTWI
KQNLYAKISGGVSNVSFSFPVREAIHSVFLYYAIKEGMDMGIVNAGQMAIYDDLPEEDVILNKDPEAGERLEEYRGDGATS----KVTDTARE-TTVEKR
LEHSLVKGITDYIEADTEEAYQKLGAPINVIEGPLMDGMNVVGDLFGSGKMFLPQVVKSARVMKRAVAYLDPYLEAEKEGQVQGKIVMATVKGDVHDIGK
NIVGVVLQCNNFEVIDLGVMVPAEKILDTAIEQNANVIGLSGLITPSLEEMVNVAKLMKERGMNLPLLIGGATTSPQY---DHPVVYVKDASRAVGVAQS
LIS
>tr|E1X3E1|E1X3E1_BACMS B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase OX=862908 OS=Bacteriovorax marinus (strain ATCC BAA-682 / DSM 15412 / SJ). GN= PE=3 SV=1
---LLELLNK-RIVFMDGAMGTMIQQYKLEEGENNDLLSLTRADIIEEVHFKYLEAGSDIIETNTFSATRIGQADHLLAYEINVESARIAKRACEKKCFV
AGALGPTNKTMSPYRAVTFDELVENYYQQAKALLEGGADILLPETTFDTLNIKCAIFAIDKLFRVPVMLSVTITSGRTLSGQTIEAFWNSVRHANPLSVG
INCALGAKEMRPYMDRLSQIADCYTSCYPNAGLPNP--LS--DYDELPIDTATFLEDYADSGLNLVGGCCGTTPSHIKAIREKLEEKKPRVKPT--LK-E
VNLSGLEPLYIDREDPFYMVGERTNVTGSPRFAKLIKNGDFDTALEVARQQVENGANIIDINFDEGLLDSKACMIKFMNLVASICKVPIMIDSSKWEVIE
EGLKCMQGKGIVNSISLKEEKFIEQAKLIKSYGAATVVMAFDEEGQAADKADKVRICQRAYKILEKVNFDPRDIIFDPNILTVATGIEEALDFIEAVKEI
KETCGVLTSGGVSNVSFSFVVREAIHSSFLYHAIKAGLDMGIVNAGMLGVYEDIEPEDVLLNRHPDATEKLEKIKGSGKKK----EVKDDKRH-GTLQER
MTHALVKGISTHIEEDTEEARQELG-PLNVIEGPLMEGMKVVGELFGSGKMFLPQVVKSARVMKAAVAYLEPFMEEERNARKQGTFVIATVKGDVHDIGK
NIVAVVLACNGYEVIDLGVMVSCEEIIKKAKEHDACIIGMSGLITPSLDEMIYNVKEFERLGFSCPIMIGGATTSPHY---SGPVAQVGDASLVVEVCSK
LLN
>tr|D5CTJ6|D5CTJ6_SIDLE Methionine synthase OX=580332 OS=Sideroxydans lithotrophicus (strain ES-1). GN= PE=3 SV=1
---IEQLLQR-RILILDGAMGTMIQRYKLTEGTCNDLLLLTQPHIIGGIHREYLEAGADILETCTFNSTSVSMEDELLAYELNVAGAKLARGLCDEPRFV
AGVLGPTGKTISPARNITFDQLVESYAEAVRGLLDGGADMLMVETIFDTLNAKAALFAIERHFRVPILISGTITSGRTLSGQTTEAFYNSLAHARPLSIG
LNCALGAELMRPYVEELARVAGCYVSAHPNAGLPNP--LSETGYDEVPETTARLVKEFATSGLNIAGGCCGTSPAHIKAIAEALRDVPPRKLPD--IEHK
CRLSGLEPFNIGDDSLFVNVGERANVTGSAKFKRLILEGNYDEALEVAKQQVETGAQVIDINMDEAMLDGEATMVKFLNLIASISKVPLMIDSSKWSIIE
AGLKCVQGKSIVNSISLKEENFIRHATLVRRYGAAAVVMAFDEQGQADTYKRKTEICKRSYDILDKVGFPPEDIIFDPNIFAVATGIEEAVDFIEATAWI
RKNLFAKISGGVSNVSFSFPVREAIHTVFLYHAIKAGMNMGIVNAGQLGVYEEIPRENVVLNRHPDAGEKLDSVKGGS-E-----QVEDLERK-GTVQER
LTHALVRGITTFIVEDTEEARLQAR-PVEVIEGPLMTGMNVVGDLFGAGKMFLPQVVKSARVMKQAVAHLIPFIEAEKSGSTKGKIVMATVKGDVHDIGK
NIVTVVLQCNNFEVVNMGVMVPCQQILDTAREHNADVIGLSGLITPSLEEMAHVAKEMERQGFRIPLLIGGATTSPNYP--SGTTVYVNDASRAVGVCSN
LLS
>tr|C1D9Z0|C1D9Z0_LARHH MetH OX=557598 OS=Laribacter hongkongensis (strain HLHK9). GN= PE=3 SV=1
---LLTNLLQSRILILDGGMGTMIQRHQLQEGSNNDLLVLTRPDVIGGIHQAYLDAGADIIETNTFNATSIAMADGMLVHEMNVAAARLVKDLCEAPRFC
AGVLGPTNRTISPYRNISFDELVSSYTEAIDGLVAGGADLLLVETIFDTLNAKAAVFAIQRYFRLPIMISGTITSGRTLTGQTTEAFYNSLSHADALSFG
LNCALGPDLLRPYVEEMSRVSAGFVSVHANAGLPNA--FG--GYDLAPADMGRAVREWAEAGINIVGGCCGTTPEHIAAIAEAVAGVAPRPRPV--ITPK
CRLAGLEPFNIGDKDLFVNVGERTNVTGSRAFAKLILNGDYATALDVARQQVENGAQIIDINMDEGMLDAHAAMVRFLNLIAAIARVPVMIDSSKWEVIE
AGLKCIQGKGIVNSISMKEDKFIEQARLVRRYGAAVIVMAFDEQGQADTFARKVEICEKSYRILDEVGFPPEDIIFDPNVFAVATGIEEGLDFIEATGWI
KQNLHAKISGGVSNVSFSFKVREAIHAVFLYHAIQRGMTMGIVNAGALEVYNEVDPEDVVLMRKDGGDEHLEKFKGEA-GK----QGEDLARD-WPVEKR
LEHALVKGITTYIEQDTEEVRAKSERPIHVIEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKAAVAYLEPFIDEEKLGPAKGVIIMATVKGDVHDIGK
NIVGVVLRCNNYKVIDLGVMVPCQTILDAAREHKADIIGLSGLITPSLEEMAYVAKEMQRQGFDIPLLIGGATTSPHY---RGPVIYVPDASRAVGVCSN
LLS
>tr|A6FBJ5|A6FBJ5_9GAMM Methionine synthase I OX=58051 OS=Moritella sp. PE36. GN=PE36_00549 PE=3 SV=1
---LEQQLKQ-RIMLIDGGMGTMIQDYKLQEGENNDLLVLSKPQLIADIHKEYLDAGADILETNTFNATTIAMADDMLSAEINREAARIARQVADEPRFV
AGVLGPTNRTISPFRNTSFDLMVEAYIESTKALIEGGSDIILIETIFDTLNAKAAVFAVKTVFELPIMISGTITSGRTLTGQTTEAFYNSLRHAEPITFG
LNCALGPDELRQYVDELSRISESYVTAHPNAGLPNA--FG--EYDLSPEDMAVHIKEWAEAGLNMVGGCCGTTPEHIKAMADAVEGVKPRQLPE--IEIA
CRLSGLEPLTIKKDSLFVNVGERTNVTGSARFKRLIKEENYDEALHVALQQVESGAQIIDINMDEGMLDSLHCMERFLNLVASISKVPIMIDSSKWEIIE
AGLKCVQGKAIVNSISLKEDNFRHQAKLIRRYGAAMIVMAFDEDGQADTQERKFQICKRSYDILNEVNFPPEDIIFDPNIFAVATGIDEAVDFIEAVKDI
KRELHAMISGGVSNVSFSFPLREAIHAVFLYYCIREGMDMGIVNAGQLAIYDDLPKEDVILNRNDNATEALEKYRDSGV------EAETQERS-FEVNKR
LEYALIKGITEFIEEDTEEARQQATLPLEVIEGPLMDGMNAVGDLFGAGKMFLPQVVKSARVMKRAVSYLNPYIEASKKSSSNGRILLATVKGDVHDIGK
NIVGVVLQCNNYEIVDMGVMVSCDDILKKAVEENCDIIGLSGLITPSLDEMVHVAKECQRKGFKLPILIGGATTSQNY---DEPVIYVSNASRAVGVVAA
LLS
>tr|Q086U0|Q086U0_SHEFN Methionine synthase (B12-dependent) OX=318167 OS=Shewanella frigidimarina (strain NCIMB 400). GN= PE=3 SV=1
---LNALLAQ-RIVILDGAMGTMIQDYKLEEGENNDLLVLSQPQIIKDIHTQYLLNGADIIETNTFNATTIAMADDMLAAEINLAGARVARQAADEPRYV
AGVLGPTNRTISPFRNVSFDQLVEAYVESTSALIEGGADIIMVETIFDTLNAKAALFAIEKVFRLPVMISGTITSGRTLTGQTTEAFYNSLRHIKPLSIG
LNCALGPKELRPYVEELSRIAECYVSAHPNAGLPNE--FG--GYDETPEEMAEVINQWAQEGLNIVGGCCGSTPAHINAIREAVLRHEPRQIPD--LPVA
CRLSGLEPLTIDKNSLFVNVGERANVTGSAKFLRLIKEEKFEEALDVVREQVENGAQIIDVNMDEGMLDGVASMAKFLNLIASISRVPIMIDSSKWEVIE
AGLKCVQGKSIVNSISMKEAKFIEQATLVKRYGAAAIVMAFDEDGQADTRERKTQICTRAYRILDVVGFPPEDIIFDPNIFAIATGIDEAVDFIESIKDI
KATLHAMISGGVSNVSFSFPVREAIHAVFLYHAIQAGMDMGIVNAGQLAIYDDIDPENVVQNLPSSNTEQLESFRGDGQVA----KKEDLARS-WPVSKR
LSHALVKGITEFIDEDTEAARLEAVRPLDVIEGSLMDGMNVVGDLFGAGKMFLPQVVKSARVMKKAVAYLNPYIELEKAGQSNGRILMVTVKGDVHDIGK
NIVGVVLACNGYEVVDLGVMVSVDKILDAVKEHNIDIIGMSGLITPSLDEMVHNVKTFHREGLTIPAIIGGATCSPHY---PHGAIYIADASRAVPMVSK
LIN
>tr|D0KYI6|D0KYI6_HALNC Methionine synthase OX=555778 OS=neapolitanus). GN= PE=3 SV=1
---LRALMHE-RILILDGAMGTMIQKRRLSEGENNDLLVLTQPKVISDIHRAYLDAGADIIEANTFNATRISMADQMLAYEINVAAARLARECADAPRFV
AGIIGPTSRTISPFRNVTFEELSSAYRESAEGLIEGGVDILLIETIFDTLNAKAAVFALEQLFRWPVMISGTITSGRTLSGQTTEAFYNSLRHAQPLSIG
LNCALGPDLLRQYVAELSRVSEFPVSVHPNAGLPNE--LG--EYDLEADPMAQQIGEWARSGINIVGGCCGTTPEHIAYMAQQVAPHPPRVPPK--PEPA
CRLSGLEPFNITPESLFVNVGERTNVTGSARFRRLIKEGDFTTALDVARQQVEAGAQIIDINMDEGLIDGEAAMERFLKLIASISRVPIMIDSSKFAVIE
KGLQWVQGKPIVNSISMKEDIFLEHARLVRRYGAAAVVMAFDEHGQADTVQRRIEICSRAYKLLEEVGFPAEDIIFDPNIFAIATGIEEAVDFIEGTRWI
KQNLHALISGGVSNVSFSFPVREAIHSVFLNHAVAAGMDMGIVNAGQLVIVDDIPAEDIVLNRRDDATDRMEKYRGSGEAK----SGADLARE-LPVNKR
LSHSLIKGIDQFVIEDTEEARLAAERPLHVIEGPLMDGMNIVGDLFGAGKMFLPQVVKSARVMKKAVAHLLPFMEAEAAGETAGKILMATVKGDVHDIGK
NIVGVVLQCNGFEIVDLGVMVPTQKILDTAIAEQCDIIGLSGLITPSLDEMVTVASEMQRQGFTLPLMIGGATTSPVY---EQPVVHVLDASRAVGVAAS
LLG
>tr|C7RJK8|C7RJK8_ACCPU Methionine synthase OX=522306 OS=Accumulibacter phosphatis (strain UW-1). GN= PE=3 SV=1
---LKARLEH-DILVLDGAMGTMIQRRGLREGTNNDLLLLTRPDIIRAIHAEYLAAGADIIETNTFNSTSASQADRLIVYELNVAGAQLARAVCDEPRFV
AGVLGPTSRTISPYRNTSFDELVDTYAEAIRGLCDGGADILLVETVFDTLNAKAALFAIERHFRWPVMISGTITSGRTLSGQTAEAFWNSLNHIRPLCFG
LNCALGAADLRQYVEELSHLCECFVSAHPNAGLPNA--FG--GYDETPEQLAAEIGDWARKGVNIVGGCCGTSPAHIAAIAASVAGVQPRVIPE--RERK
LRLSGLEPFNVGRDSLFVNVGERTNVTGSRAFARMILEGRFDDALAVARQQVENGAQVIDINMDEAMLDSQAAMDRFLKLIASISRVPIMLDSSKWEVIE
AGLKCIQGKGIVNSISMKEAEFLRQARLARRYGAAVVVMAFDETGQADTYTRKTEICARAYRLL--AAFPPEDIIFDPNIFAIATGIEEAVDFIEACAWI
RAHLGAQISGGVSNVSFSFAVREAIHTVFLYHAVKAGLSMGIVNAGMLGVYDDLDPEDVVLNRRPDAGEALQTVKGRS-EGM---GGPDLARD-FEVEAR
LTHALVKGINDFVVADTEECRATVESPLSVIEGPLMNGMNVVGDLFGAGKMFLPQVVKSARVMKQAVAHLIPYIEAEKTGSSKGKIVIATVKGDVHDIGK
NIVGVVLGCNGYDVVDLGVMVGCDKILHAAREHGAQAIGLSGLITPSLEEMSHVAAEMERLGFAVPLLIGGATTSPNY---SGPVVYVPDASRAVGVVTK
LLS
>tr|K2M5U7|K2M5U7_9RHIZ B12-dependent methionine synthase OX=391937 OS=Nitratireductor pacificus pht-3B. GN= PE=3 SV=1
---LRAAASE-RILVLDGAMGTQIQQLGFDEGDNNDLLILTQPKAIEDIHYAYAMAGADIIETNTFSSTSIAQADGMTVYELNRDGARLAKRAVRRRRFV
AGALGPTNRTISPYRAVTFDDLRTAYGEQLRGLIDGGSDIILIETIFDTLNAKAAIFACEEIFHLPVMISGTITSGRTLSGQTPTAFWHSVRHARPFTVG
LNCALGAAAMRPHLAELSSVSESFTCAYPNAGLPNA--FG--QYDESPEQMAAQVEDFAREGVNVVGGCCGSTPEHIAAIRDAVAKYEPRKPAK--PAPL
MRLSGLEPFTLSDDIPFVNVGERTNVTGSAKFRKLITAGDYATALDVARDQVANGAQIIDINMDEGLIDSTGAMVEYLNLIAAIARVPVMIDSSKWEVIE
AGLKCVQGKPIVNSISMKEEAFLHHARLCRMYGAAVVVMAFDKVGQADTKDRKVEICTRAYKLLEKAGFAPEDIIFDPNVFAVATGIEEGVDFIEATGEI
VDTLHVHISGGVSNLSFSFPVREAMHAVFLYHAIQRGMDMGIVNAGQLAVYESIDPEDVVLNRVPKATERMERFKGQG-EA----KEKDLARE-WPVEKR
LEHALVNGITEFVEQDTEEARLNAERPLHVIEGPLMAGMNVVGDLFGAGKMFLPQVVKSARVMKQAVAVLLPYMEAEKNRRSAGKILMATVKGDVHDIGK
NIVGVVLACNNYEIIDLGVMVPATKILETAKAENVDIIGLSGLITPSLDEMVHVAAEMEREGFDIPLLIGGATTSPRYD--RGQAVYVTDASRAVGVVGN
LLS
>tr|A7JW42|A7JW42_PASHA Methionine synthase OX=272629 OS=Mannheimia haemolytica PHL213. GN= PE=3 SV=1
---LQNALTE-RILILDGAMGTMIQKYKLTEGENNDLLTLTQPLLISAIHEKYLAAGADIIETNTFSATTIAQADELIAYELNLVGAKLARLAADKPRFV
AGILGPTNRTISPFRNITFMQLVEAYAEATRGLIEGGADLIMIETIFDTLNAKAAVFAIETVFKLPIMISGTITSGRTLSGQTTEAFYNSLRHAKPLTFG
LNCALGPKELRPYVEMMSKISETFVSVHPNAGLPNA--FG--GYDLGAEEMATYIKEWAELGLNIVGGCCGTTPEHIQAFAEATKGVAPRKLPE--IPTA
MRLSGLEPLTIDDNSLFVNVGERNNVTGSAKFKKLIKEEKFAEAIEIAISQVENGAQVIDVNMDEALLDSKKCMTRFLNILATAAKVPIMIDSSKWEVIE
AGLQTVQGKPIVNSISLKEEKFIHQAKLCRRYGAAVVVMAFDEVGQADTEERKVEICTRAYRILDQLGFPPEDIIFDPNIFAIATGIEEGVDFIQACERI
KRDLHAKISGGVSNVSFSFVVREAIHAVFLYYAIKAGMDMGIVNAGQLAIYDDLDPEDAVLNHRHDTTDRLEKYRGVKESA----DESAAERN-LPVAER
LKHALVKGITTYIIEDTEEARQQFASPLEVIEGPLMAGMDVVGDLFGDGKMFLPQVVKSARVMKQSVAYLEPYINATKKGSSNGKMVIATVKGDVHDIGK
NIVSVVLQCNNFEVIDLGVMVPADVIIETAIREKADLIGLSGLITPSLDEMEYFLGEMNRLKLDIPVLIGGATTSPKY---NYPVVYTANASRCVTVCAT
LMN
>tr|Q608E7|Q608E7_METCA 5-methyltetrahydrofolate--homocysteine methyltransferase OX=243233 OS=Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath). GN= PE=3 SV=1
---LKRLLKE-RILFLDGAMGTMIQRYKLAEGQNNDLLSLTRPDVIEAIHWAYLEAGADIVETNSFNATRISMADGMLVYEINVASARLARQVADRPRFV
AGVLGPTSRTISPFRNIGFDELVASYDEAVRGLVDGGADIILIETIFDTLNAKAAVFAVERFFTLPVMISGTITSGRTLSGQTTEAFWNSLRHARPISIG
LNCALGAKQLRQHVEELSRIADTYVSAHPNAGLPNE--FG--EYDESPEAMAREIADWAEQGLNIIGGCCGTTPAHIEAIHDAVQHFPPRRIPE--IPPA
CRLAGLEPCNITAGSLFVNVGERTNVTGSAAFRRMIREAKYDEALEVARQQVESGAQIIDVNMDEGMLDSRAAMVQFLNLIAAIARVPVMIDSSKWEILE
AGLKCLQGKGIVNSISLKEAAFLHHARLVRRYGAAVIVMAFDEQGQADTRERKVEICERAYRLLEKAGFPAEDIIFDPNIFAVATGIEEGLDFIEAVAEI
KSRLHALVSGGVSNVSFSFAVREAIHAVFLYHAIRAGMDMGIVNAGQLAIYEEVPEEDVILARREDATERLDRYRGGA-SE----RKADMARS-LPVDKR
LEHALVKGIDEFIEVDTEEARRQFERPLHVIEGPLMAGMNVVGDLFGAGKMFLPQVVKSARVMKKAVAYLMPYMDAEKTEGTNGKILMATVKGDVHDIGK
NIVGVVLQCNGFEVIDLGVMVPCDKILQTAREENVDIIGLSGLITPSLDEMVHVAREMERLGFEIPLMIGGATTSPNY---HGPTVYVTDASRSVGVAGS
LLS
>tr|Q3SM63|Q3SM63_THIDA 5-methyltetrahydrofolate--homocysteine methyltransferase OX=292415 OS=Thiobacillus denitrificans (strain ATCC 25259). GN= PE=3 SV=1
---LHSLLAQ-RILVLDGAMGTMIQSYKLGEGENNDLLCLTQPAIIKEIHAKYLAAGADILETNSFNATAISMADRMLVPELNFAAAKLAREAADEPRFV
AGVLGPTSRTISPFRNVTFDQLREAYLEAIDGLVKGGADILMVETIFDTLNAKAALFAIEEYFRLPVMISGTITSGRTLSGQTGEAFWNSVRHARPLSIG
LNCALGPDLLRQYVEELSNKAEVFISAHPNAGLPNA--FGE--YDMDGAEMAKHIGEWARAGLNIVGGCCGTSPSHIAAIAKAVEGVAPRVPPV--LEPA
MRLSGLEPFNVGKDSLFVNVGERTNVTGSKAFARMILEGRYDDALSVARQQVENGAQVIDINMDEGMLDAEAAMVRFLHLIASIARVPIMIDSSKWNVIE
AGLKCIQGKGIVNSISMKEAEFIERAKLCLRYGAAVIVMAFDETGQADTYARKTEICTRAYKLLETVGFPAEDIIFDPNIFAVATGIEEAVDFIEATRWI
RQNLYAHVSGGVSNVSFSFAVREAIHTAFLYHAIQAGMDMGIVNAGQLGVYENLDPEDVLLNRRADATERLEGVKGGA-E-----KVEDLARS-LPVNER
LTHALVQGITQYIVEDTEAARLEAE-PLHVIEGPLMAGMNVVGDLFGAGKMFLPQVVKSARVMKQAVAHLIPYIEADKGDQSAGKIVMATVKGDVHDIGK
NIVGVVLGCNGYEIVDLGVMVPAQKILDAAREHKADIIGLSGLITPSLEEMAHVAKEMQRQGFTIPLLIGGATTSPNY---EHPVVYVKDASRAVGVCTQ
LLS
>tr|Q0AIP5|Q0AIP5_NITEC Methionine synthase (B12-dependent) OX=335283 OS=Nitrosomonas eutropha (strain C91). GN= PE=3 SV=1
---LKQLLAE-RILILDGAMGTMIQSYKLSEGENNDLLCLTKPEVIRAIHRAYLEAGSDIIETNTFNSNAPSMADHMLVYELNVAGARLACEEARAPRFV
AGVIGPTTKTLSPFRAITFDDLVESYTESVSGLVDGGADILLVETIFDTLNAKAALFAIEQYFRLPVMISVTITSGRNLSGQTPEAFWNSVRHARPLSVG
INCALGAELMRPYVQELSNVSEVCTSAHPNAGLPNP--LAETGYDETPEYTARLIKDFAQSGVNIVGGCCGTTPEHIAAIVEAVQDIPPRKLPD--LPKK
LRLSGLEPLSIDESSLFVNVGERTNVTGSKAFARLVLSGNYAEGLVIARNQVESGAQIIDINMDEGMLDSQKAMVTFLNLVASISRLPIMVDSSRWSVIE
AGLKCIQGKAIINSISLKEEEFLLHAKLARRYGAAVIVMAFDESGQADTLQRKVDICTRSYHTLERADFPPEDIIFDPNIFAIATGIEEAVDFIEATRLI
RQTLYAKISGGVSNVSFSFPIREAIHTAFLYHAVKAGMTMGIVNAGQLGVYSDIPPEDVLLNRRPDATERLENFKGQK-E-----QAEDLARD-EPVRQR
LIHALVRGINTYIVEDTELIRQEIDSPIEVIEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKQAVAYLLPYIEAEKSGKPKGKLVIATVKGDVHDIGK
NIVSVVLQCNNFEVVNLGVMIPSAQILETARRENADMIGVSGLITPSLEEMAHVAREMEREQFTIPLLIGGATTSPHY---SGVTIWVPDASRAVGVCSN
LMS
>tr|K0C5W5|K0C5W5_CYCSP 5-methyltetrahydrofolate--homocysteine methyltransferase, MetH OX=385025 OS=Cycloclasticus sp. (strain P1). GN= PE=3 SV=1
---LLDLLKQ-RILLLDGAMGTMIQSYDFNEGENNDLLSLTQEDTIRAIHLAYFEAGADIVETNTFNSTRVAMADDMLSYEINEQSARIARKAADEVCFV
AGVLGPTNRTISPFRNISFDELAEAYTESIDALIKGGVDIILVETIFDTLNAKAALYAIQMYFEYPVMISGTITSGRTLSGQVTEAFWNSLRHIKPISIG
FNCALGAEELRQYVEELSRVADTYISAHPNAGLPNE--FG--GYDETPDDMAGHIREWAQSGLNIIGGCCGTSPEFITAMKEAVSDSAPREIPK--LEVA
CRLSGLEPMNIFKDSLYVNVGERTNVTGSARFKRLIKEQDYETALDVARQQVESGAQVIDINMDEGMLDSKAAMIRFLSLIAAISVVPVMIDSSKWDILE
AGLKCVQGKAIVNSISLKEENFINQAKTIMRYGAAVIVMAFDETGQADTFERKVEICTRAYKVLEKVGFPAEDIIFDPNIFAIATGIDEAVDFIEATRVI
KQTLHAMVSGGVSNVSFSFKVREAIHAVFLYYAVQAGMDMGIVNAGQLAVYDDIPDEDVILNRTPKATENLEKYEGDSEA-----VKEAAERS-WPVKKR
LEHALVKGITEFIEEDTELVRQEVERPLHVIEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKKAVAYLMPFMEEEKVVETNGKVLMATVKGDVHDIGK
NIVAVVLQCNGFEVVDLGVMVPADTILKEASKHNVDVIGLSGLITPSLDEMVHMAKEMERQGFDIPLMIGGATTSPHY---HGVSVYVTDASRSVGVLSN
LMD
>tr|F6DB73|F6DB73_THICA Methionine synthase OX=717773 OS=Thioalkalimicrobium cyclicum (strain DSM 14477 / JCM 11371 / ALM1). GN= PE=3 SV=1
---LKQLLTE-RVVVLDGAMGTMIQGLQLTEGENNDILVMTKPEVIRDIHLGFLRQGVDILETNSFNATTIAQADDMQVRAINICAAKVAREACDIPRFV
AGVLGPTNRTISPFRNTSFDELVGAYVQATEALLEGGADVILIETIFDTLNAKAAIFAVKQVEELPIMISGTITSGRTLSGQTTEAFYNAIRHAKPLSVG
LNCALGPKELRPYVEELSRIAECYVSVHPNAGLPNE--FG--EYDETPEQMAAEVQTWAQAGLNIIGGCCGTTPDHVEAMAKAALAHPQRIIPT--IKKA
CRLSGLEPMTIDDTTLFVNVGERNNVTGSALFKRLIIEDNYEQAVEIAVKQVNDGAQIIDVNMDEGMLDAKACMSRFLNMMAGAARVPVMIDSSKWEAIE
AGLKCIQGKGIVNSISLKEENFLAQAKLIQRYGAATIVMAFDEDGQADTFARKKEICQRSYDLLAN-GFPPEDIIFDPNIFAVATGIEEAVDFIEATGWI
KQNLYAMISGGVSNVSFSFPVREAIHSVFLYYAIQQGMDMGIVNAGQMAIYDDLDPEDVILNKDPEAADRLEKFRGDGVQG----KESDIKRE-ASVEKR
LEHALVKGITDFIEDDTEEARTTLGSPLQVIEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKRAVAYLQPFLEAEKSGQAKGKIVMATVKGDVHDIGK
NIVGVVLQCNNFEVIDLGVMVPAEKILDTALREGANVIGLSGLITPSLEEMVHVAKEMQRRGMSIPLLIGGATTSPQY---EHPVVYVKDASRAVGVAQS
LIS
>tr|C4L880|C4L880_TOLAT Methionine synthase OX=595494 OS=Tolumonas auensis (strain DSM 9187 / TA4). GN= PE=3 SV=1
---LHQSLQE-RILLIDGGMGTMIQSYQLQEGENNDLLVLTKPDVIAAIHDAYLAAGADILETNSFNATRIAMADHMLSAEINREAARLARKAADEPRFV
AGVLGPTNRTISPKRNVTFDALVEAYKESTEALIEGGVDIIMIETIFDTLNAKAAFFAVDTIFKLPVMISGTITSGRTLSGQTTEAFYNSLRHAEPLSFG
LNCALGPKELRQYVQELARISETYVSVHPNAGLPNA--FG--GYDLEADEMAEHIREWAESGLNMVGGCCGTTPEHIRAMAKAVDGIKPRVLPE--LPVA
CRLAGLEPLTIDENSMFVNVGERTNVTGSAKFKRLIKEEQYDEALDIARQQVISGAQIIDINMDEGMLDAQACMVRFLNLIASISRVPIMIDSSKWEVIE
AGLKCIQGKGIVNSISMKEEKFIAQAKLLRRYGAAVIVMAFDEVGQADTRARKFEICQRAYKILEQVGFPPEDIIFDPNIFAVATGIDEAVDFIEAVKDI
KTNLHAMISGGVSNVSFSFQVREAIHSVFLYYTIKNGMDMGIVNAGQLAIYEDIPAEAVVLNTHPGATEELEKYRGGAQQAI---DPREQERS-WPVGKR
LEHALVKGITDFIDEDTEEARQLAARPIEVIEGPLMAGMNVVGDLFGAGKMFLPQVVKSARVMKRAVAYLQPYIEQGKAGQTNGKIVMATVKGDVHDIGK
NIVGVVLQCNNYEIVDLGVMVSCEKILQTAREVNADIIGLSGLITPSLDEMVHVAKEMERQGFKIPLMIGGATTSQNY---SEPVVYVSNASRAVGVVQN
LLS
>tr|J9DJ06|J9DJ06_9PROT Methionine synthase OX=1220535 OS=alpha proteobacterium IMCC14465. GN=IMCC14465_03100 PE=3 SV=1
---LPRLTEQ-RILTLDGAMGTMIQRHKPDEGSNNDLLSLTQPDMIRDIHTAYLEAGADILETNTFSSTTIAQADELFAYEMNVIGAKLAREACDTPRYV
AGALGPTNRTISPMRNVHYDELVEAYAAATRGLIEGGADIIIVETVFDTLNAKAALHGVQSVFRLPLMVSGTITSGRTLSGQTTEAFWNSIKHCKPFSVG
LNCALGAEEMRPYVAEIARIADTNICIYPNAGLPNE--FG--EYDQMAAEMASIVGEFAESGVNILGGCCGTTPDHIAAISTAAGQNNPRPIPE--IDKR
LRLSGLEPFTMTEDIRFVNIGERTNVTGSAKFRKLITDNDYEAALDVARQQVENGAQIIDVNMDEGMLDSEAAMTKFLNLAATIARVPVMIDSSKWSVIE
AGLKCVQGKAVVNSISLKEAEFLEHARLCLRYGAAVIVMAFDEQGQADTADRKFEICKRSYHLLDEVGFPPEDIIFDPNIFAVATGIEEAVDFIEATKRI
RQELGAHVSGGVSNISFSFAVREAMHSAFLYHAIHSGMDMGIVNAGQLAIYEDIDAEDVLLNANDNATDHLEGFLGQG-AK----QEADLSRE-GSVPER
LMHALVNGIGDFIEEDTELARQGFDRPLNVIEGPLMDGMNRVGDLFGDGKMFLPQVVKSARVMKKAVAYLEPFMDKEKASSSKGKVLMATVKGDVHDIGK
NIVGVVLQCNNFDVIDMGVMVPANDIIDRAVEEQVDIIGLSGLITPSLDEMCHVAAEMERRGLNIPLLIGGATTSPNYE--RGQTVYVTDASRAVGVASR
LLS
>tr|F8GH06|F8GH06_NITSI Methionine synthase OX=261292 OS=Nitrosomonas sp. (strain Is79A3). GN= PE=3 SV=1
---LESLFAQ-RILILDGAMGTMIQTFKLTEGQNNDLLTLTQPQVIRSIHTGYLEAGADILETNTFNSNAASMADHMLVYELNCSAAKLAREAAQSPRFV
AGVIGPTTKTISPFRGITYDQLVVDYTESIRGLVDGGVDILLVETIFDSLNAKAALFAIDQFFRLPIMISVTITSGRTLSGQTPEAFWNSVSHTRPISVG
INCALGAELMRPYIEELAGVADVYTSVHPNAGLPNP--LSDTGYDESPEYTANQIKGFAQSGVNIVGGCCGTTPAHIKAIAQAVSDIAPRKIPE--IPKK
LRLSGLEPLNIGDDSLFVNVGERTNVTGSRAFARLILNDDYAEALNVARSQVESGAQIIDINMDEAMLDSQKAMVTFLNLVAAICKVPIMLDSSKWTVIE
AGLKCVQGKSIINSISMKEEEFIKHAKLARRYGAAVIVMAFDEQGQADTLKRKVDICTRSYRLLDQVGFPPEDIIFDPNIFAIATGIEEGVDFIDATRII
KQTLYAKVSGGVSNVSFSFPIREAIHTAFLYHAIKAGMTMGIVNAGQLGVYTDIPAEDVILNRRADATEHLENFKGKK-E-----QVEDLARA-EPLQQR
LTHALVRGIDTFIVEDTEAARVEIENPIQVIEGPLMEGMSVVGDLFGAGKMFLPQVVKSARVMKQAVAHLLPFIEAEKSGKPKGKIVIATVKGDVHDIGK
NIVTVVLQCNNYEVINMGVMVPSAQILDMARREKADIIGLSGLITPSLEEMAHVAKEMQREGFTIPLLIGGATTSPHY---EGATVWVPDASRAVGVCTN
LLS
>tr|E1V310|E1V310_HALED B12-dependent methionine synthase OX=768066 OS=2198 / 1H9). GN= PE=3 SV=1
---LTDSLAE-RILMLDGGMGTMLQNAGLSEGENNDLLALTCPDLVTRIHRDYLEAGADIVETNTFNSTRLSQADGMLVPELNRESARLARAICDAPRYV
AGVLGPTSRTLSPMRNVTFDELRDNYREAAEALIEGGSDLILIETIFDTLNAKAAIYALEELFRLPVMISGTITSGRTLSGQTTEAFWNSVRHTRPLSVG
LNCALGAEELRPYVEELAKKADTFVSAHPNAGLPNE--FG--EYDQTPEEMAAIVAEFAESGVNIIGGCCGSTPEHIAAIHRAIRDTAPRRIPE--RALA
CRLSGLEPFNIEHDSLFVNVGERTNVTGSARFKRLIKEEDYTTALEVALEQVENGAQVIDINMDEGMLESQDAMVRFLNLIAGIARVPIMVDSSKWEIIE
AGLKCIQGKAVVNSISLKEDAFREQATKCRRYGAAIVVMAFDEQGQADTFARKAEICQRAYRLLDEIDFPAEDIIFDPNIFAIATGIEEAVDFIEATRWI
REHLHAMVSGGVSNVSFSFAVREAIHSVFLYHAIRAGMTMGIVNAGQLAVYDDLPEEDVVLNRRDDATERLDKYKDDG-GA----SRKEDERS-WEVEKR
IEHALVKGITAYIEDDTELARQRATRPIEVIEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKQAVAYLIPYIEAEKEDQAKGKIVMATVKGDVHDIGK
NIVGVVLQCNNYEVIDLGVMVPAEKILQTAREENADIIGLSGLITPSLDEMVHVAKEMQRQNFDIPLLIGGATTSPGY---EHPVIYVTDASRAVGVAGK
LLS
>tr|Q2SJ31|Q2SJ31_HAHCH 5-methyltetrahydrofolate--homocysteine methyltransferase OX=349521 OS=Hahella chejuensis (strain KCTC 2396). GN= PE=3 SV=1
---LNDSLKK-RILILDGAMGTMIQRYKLEEGENNDLLCLTQPHIIQAIHKAYLDAGADIIETNSFNATWVSQAEGLIVYELNVASAQVARAAADEPRFV
AGVLGPTSRTISPYRNVDFQTLVDNYYEATKGLVDGGSDIILIETIFDTLNAKACIYAVQQYFELPIMISGTITSGRTLSGQTAEAFWNSVAHSRPISIG
LNCALGADALRPYVEELSNRATTYISAHPNAGLPNE--FG--EYDQTPEEMAAIVEGFAQDGVNIIGGCCGTTPDHIAAIKKAVEKHAPRAIPD--ITPR
LRLSGLEPFTLTDEIRFVNVGERTNVTGSRRFLRLIKEECYEEALDVARDQVENGAQVIDINMDEGMLESADAMKLFLNLIASISKVPIMVDSSKWEVIE
AGLRCIQGKAVVNSISLKEADFIAKAKSCMRYGAAVVVMAFDEAGQADTYERKTEICKRSYDILG-LGYPPQDIIFDPNIFAIATGIEEAVDFIQATRWI
RQNLYANVSGGVSNVSFSFTVREAIHSVFLFHAINAGMNMGIVNPAQLVIYDEIPAEDVVLNKHPDATERLERYRSTG-KK----QEESQERS-WPVTKR
LEHALVKGINAYITEDTEEARLAAARPIEVIEGPLMDGMNVVGDLFGSGKMFLPQVVKSARVMKQAVAHLIPYIEQEKAKKAKGRILMATVKGDVHDIGK
NIVGVVLQCNNYEVIDLGVMVPCEKILQVAKEENVDIIGLSGLITPSLDEMVHVAREMQRLNFKIPLLIGGATTSPEYK--NDVTVYVTDASRSVSVATR
LMS
>tr|A6EVN6|A6EVN6_9ALTE 5-methyltetrahydrofolate--homocysteine methyltransferase OX=443152 OS=Marinobacter algicola DG893. GN=MDG893_06745 PE=3 SV=1
---LEQALKE-RIIVLDGGMGTMIQNLKLDEGDNNDLLNLTQPALLRNIHADYLEAGADIIETNTFNSTQLSQADGLIAKELNVEAAKLARQIADEPRFV
AGAVGPTSRTISPYRNVDFQTLVDNYYEAVEGLVQGGSDLILIETIFDTLNAKAAIYATQQYFELPIMISGTITSGRTLSGQTTEAFWNSVSHARPVSVG
LNCALGADALRPYVEELSNKSTTYVSAHPNAGLPNE--FG--EYDQTPEEMAEIIEGFARDGLNIIGGCCGSRPDHIEAIADAVAKYPPRKIPN--QKPA
LRLSGLEPFTGDENTLFINVGERTNVTGSKRFLRLIKEEQYEEALSVARDQVENGAQIIDINMDEGMLDSKDVMVTFLNLVASISRVPIMIDSSKWEVIE
AGLRCIQGKAVVNSISLKEEEFLKRARDCMRYGAAVVVMAFDEDGQADTFERKTEICKRSYDLLG-IGFTAGDIIFDPNIFAIATGIEEAVDFINASRWI
RDNLHASISGGVSNVSFSFAVREAIHSVFLYHAIKAGMNMGIVNPGQLVIYDEIDPEDVVLNRRDDATDRLERYRSKG-KT----QEEDLARE-WPVEKR
VEHALVKGITNYIIEDTEACRQRAARPIEVIEGPLMDGMNVVGDLFGDGKMFLPQVVKSARVMKQAVAHLIPYIEAEKGDQAKGKILMATVKGDVHDIGK
NIVGVVLQCNNYEVIDLGVMVPCDKILDVAKKENVDIIGLSGLITPSLDEMVHVAKEMQRLDFNIPLMIGGATTSPQYK--NDIALYVSDASRCVNVASQ
LLS
>tr|Q2BMJ6|Q2BMJ6_NEPCE Cobalamin-dependent methionine synthase OX=207954 OS=Neptuniibacter caesariensis. GN=MED92_04362 PE=3 SV=1
---LSESLKQ-RIMILDGGMGTMIQDYKLEEGENNDLLVLTKPEIIKAIHKEYLEAGADIIETNTFNATQIAMADEMLSREINVEAARLAREACDEPRYV
AGVLGPTNRTISPFRNVSFNDLVEAYTESIDGLVEGGSDIILIETIFDTLNAKAAIYAVETYFRLPVMISGTITSGRTLSGQTTEAFWNSVRHAKPISVG
LNCALGPKELRQYVEELSRISETFVSTHPNAGLPNA--FG--GYDETPEQMATEISEWAQSGLNIIGGCCGTTPAHIKAMREAVENEAPRALPQ--LPVE
SRLSGLEPMNIGEDTLFVNVGERTNVTGSAMFKRLIKEQDYETALDVARQQVENGAQIIDINMDEGMLDAHAAMVKFLNLIASIARVPIMIDSSKWDVIE
AGLQCIQGKGIVNSISLKEDNFIEQAKKLRRYGAAVVVMAFDETGQADTYERKIEICERSYRVLDQVGYPPEDIIFDPNIFAVATGIEEAVDFIQATGWI
KQNLYAKVSGGVSNVSFSFPVREAIHCVFLYHAIKQGMDMGIVNAGQLAIYDDLPEEDVIQNSRDDATERLEKYRGDGQED----DTKTQERS-WDVNKR
LEHALVKGITEFIEDDTEEARQNHERPLHVIEGPLMDGMSVVGDLFGAGKMFLPQVVKSARVMKKAVAYLMPFIEEEKTSQSNGKIVLATVKGDVHDIGK
NIVGVVLQCNNYEIIDLGVMVPAETILRTAREENADLIGLSGLITPSLDEMVHMAKEMERQEFNIPLLIGGATTSPAF---NRDVVHVTNASRAVNVASS
LLG
>tr|G2FIT3|G2FIT3_9GAMM Methionine synthase OX=1049564 OS=endosymbiont of Tevnia jerichonana (vent Tica). GN= PE=3 SV=1
---LESILCE-RILILDGAMGTMIQRHKLTEGENNDLLVLSQPELIRNIHEEYMEAGADILETNTFGANRISMADDMLAYEMNVAGARLCREAADKPRYV
AGVLGPTNRTISPARNISFDELVEAYAEATRGLIEGGVDILLIETIFDTLNAKAAVAACEQVFRLPIMISGTITSGRTLSGQTTEAFYNSLRHARPISIG
LNCALGPELMRQYVEEISRVAECYVNVHPNAGLPNE--FG--EYDLGPEAMGQQIAEWAEAGLNIIGGCCGTTPAHIKAIAEAVADQAPRKLPE--IRPE
CRLSGLEPLNIGPDSLFVNVGERANVTGSAKFKRLILNEEYEEALDVCRAQVENGAQVVDVNMDEAMLDGVAAMQRFLNLCAGISKVPVMIDSSKWEIIE
AGLKCVQGKPIVNSISMKEDKFKQQAKLCRRYGAAVIVMAFDEEGQADTQARKVEICTRAYQILEEVGFPAEDIIFDPNIFAVATGIPEGVDFIEATREI
KAACHALISGGVSNVSFSFPVREAIHAVFLYHAIQAGMDMGIVNAAQLAVYDDLPAEDVVLNKDPEAGDRLPNYAGDG--N----KVEDLERS-WPVNKR
LEHALVKGITEYIDTDTEEARLAVDKSLEVIEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKKSVAYLEPFLEAEKECQAQGKILMATVKGDVHDIGK
NIVGVVLQCNNYEVIDIGVMVPADTILKQAQEHQVDIIGLSGLITPSLDEMVHVAKEMKRLRMSQPLMIGGATTSPEY---DHPVVYVPDASRAVGVASN
LLS
>tr|B7RVB9|B7RVB9_9GAMM Methionine synthase OX=247634 OS=marine gamma proteobacterium HTCC2148. GN= PE=3 SV=1
---LIQSLQQ-RILVIDGAMGTMIQEEGLEEGENNDLLCLTRPDIIEKIHLEYLEAGADLIETNSFNATSIGQDDQLLAYELNLASAKVARKAADAPRFV
AGVLGPTPKTISPARSITFDQLSEVYLEATLALIEGNVDLLLIETVFDALNAKAAIFAVKEAFELPIMISVTFPSGRVLSGQNPEAFYNAIAHANPLIVG
SNCGRRYSEIRPFLEELSNVSDCYFSAHLNAGLPNA--FG--EFDETPEIMHDDFREFAQRGLNLAGGCCGTTPAHIRAIADAVADVEPRKLPD--IAPA
CRLSGLEPFNISADSLFVNIGERCNVTGSAKFKRLILDDDYEAALEVARIQVEDGAQIIDVNMDEGMLDAEKAMVTFLNLIASISRVPIMVDSSKWSAIE
AGLKCIPGKPVVNSISLKAEEFIEQARLCLRYGAAVVVMAFDEDGQADNLERRKQICKRSYDLLDKIGFNPRDIIFDPNIFAVATGIEEAVDFIEGTRYV
KQALGALVSGGVSNVSFSFAVREAIHSVFLYHAIKAGMDMGIVNAGQLAVYDDLPDEDVVLNRREDGTERLEQYRETG-GG----RKEDLSRE-QDVSKR
IEHALVKGINTYVVEDAEEARLQFDRPIQVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAHLQPFIEEEKG-SSNGKILMATVKGDVHDIGK
NIVGVVLQCNNFEVIDLGVMVACEEILRVAKEEQVDIIGLSGLITPSLDEMVHVASEMQRLDF-VPLLIGGATTSPQYT--NDIVAYVPDASRSVSVATQ
LMN
>tr|Q21J59|Q21J59_SACD2 Methionine synthase (B12-dependent) OX=203122 OS=Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024). GN= PE=3 SV=1
---LYAALEE-RILILDGAMGTMIQSYKLQEGENNDLLALTQPVILRDIHRAYLDAGADILETNTFNSTQISQADDTIAYELNKESAAIARAVADEPRFV
AGVLGPTSRTISPARNVTYDELVTNYKEATLGLIEGGADIILIETIFDTLNAKAAVFAVKTVFELPIMISGTITSGRTLSGQTTEAFYNSLAHAKPLSIG
LNCALGAAELEPYVRELSRVSNCYVSAHPNAGLPNE--FG--EYDQSAKEMADVVEKFAVKNVNIIGGCCGTTPQHIKAIAETVSKYPARKIPD--IEPQ
CRLAGLEPFNISKDSLFVNVGERCNITGSARFKRLILEGDYTTAIEVALQQVTDGAQIIDINMDEGMLDAEAAMIKFLNLLAGIARVPIMVDSSKWDVIV
AGLKCIQGKPIVNSISLKEAEFIERARLCKLYGAAVIVMAFDEDGQADTAQRKIEICERSYKVLEQAGFPPEDIIFDPNIFAVATGIEEAVDFIEATRWI
RQNLYAGVSGGVSNVSFSFPVREAIHSVFLYYAIQAGMNMGIVNAGQLAIYDDLPKEDVILNKNDNGTEALEQYRGDG-AQ----ASKEDARE-LPVEKR
LEHSLVKGISAYIEADTEEARQNASKPIDVIEGPLMAGMNVVGDLFGSGKMFLPQVVKSARVMKQSVAYLQPFIEAEKEGRSNGKILMATVKGDVHDIGK
NIVGVVLQCNNFDVVDLGVMVPCEKIIDTAIAENCDMIGLSGLITPSLDEMVNVAREMQSRQVNLPLLIGGATTSPQFS--LNQAVYVADASRAVGVASK
LLS
>tr|K0CFU2|K0CFU2_ALCDB Dihydropteroate synthase OX=930169 OS=Alcanivorax dieselolei (strain DSM 16502 / CGMCC 1.3690 / B-5). GN= PE=3 SV=1
---LTSLMQD-RIVILDGGMGTMIQRLKLNEGANNDLLSITQPEKIEALHRAYLEAGADIIETNSFNSTAIAMADDMLAHELNKASAEVARRAADAPRFV
AGVLGPTNRTISPYRNVNFDALVEAYLEAVDGLVQGGSDLILIETIFDTLNAKAAVFAVDQYCDLPVMISGTITSGRTLTGQTTEAFYNSLRHARPISMG
LNCALGPMELRPYIEELSRISEFHVSAHPNAGLPNE--MG--EYDLDPDTMAKEIRGWAQKGLNIIGGCCGTTPEHIAAMAEAVRDCAPRALPA--IPVQ
CRLSGLEPCSIAPDSLFVNVGERTNVTGSKRFLRLIKEGDYDTALDVARDQVENGAQIIDINMDEGMLDSLECMVRFLNLVASISKVPIMIDSSKWEVIE
AGLKCIQGKGVVNSISLKEEAFLNQARLIRRYGAATVVMAFDENGQAETREQKVAICSRAYKLLEEVGFPPEDIIFDPNIFAIATGIEEAVDFIEAVAEI
KRTLHALISGGVSNVSFSFPVREAIHAVFLYHAIQSGMDMGIVNPSQLAIYADIPAEDVVMNRREDGTERLEKYRDSGKEV----KKEDQERS-WPVEKR
LEHALVKGIADHVESDTEEARLRAERPLHVIEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKKAVAYLLPFMEKEKQDESNGRILMATVKGDVHDIGK
NIVGVVLQCNGYEVIDLGVMVPCDKILETARAEKVDIIGLSGLITPSLDEMVHVASEMERLEMDLPLMIGGATTSPNY---HHAVIHVADASRAVGVVSR
LLS
>tr|I3CD57|I3CD57_9GAMM 5-methyltetrahydrofolate--homocysteine methyltransferase OX=395493 OS=Beggiatoa alba B18LD. GN=BegalDRAFT_0638 PE=3 SV=1
---FQSLLKQ-RLLFLDGAMGTMIQRYKLQEGTNNDLLVLTQPQIIREIHRQYLEAGADILETNTFNSTRISMADDMLVYELNHAAAALAREVADEPRFV
SGVLGPTSRTISPYRNVLFDELVENYYEAIDGLVNGGADILLIETIFDTLNAKAAIFSVEKYFRLPVMISGTITSGRTLSGQVTEAFWNSLRHAQPISIG
LNCALGAKQLRQYVEELSRIADTYVSAHPNAGLPNE--FG--EYDELPEVMAKEIEDWAKSGLNIIGGCCGTTPPHIKAIYETLRHYPPRVVPD--IPPA
CRLSGLEPFNITAESLFVNVGERTNVTGSAQFKRMIKEENYEAALEVARQQVENGAQVIDINMDEGLLDSKAVMIKFLNLLASIARVPIMVDSSKWEVLE
AGLKCIQGKGIVNSISMKEAKFIEQAKLVRRYGAAVVVMAFDEVGQADTFARKVEICSRSYELLKVVGFPAEDIIFDPNIFAVATGIEEAVDFIQATEII
KKTLHALISGGVSNVSFSFPVREAIHSVFLYHAIKAGLSMGIVNAGQLAIYEDLPSEDVVLNRRADSTERLEKYKGGATQE----NQQDLARS-LPVGKR
LEHALVKGITDFIEVDTEEARQQYARPLQVIEEPLMNGMNVVGDLFGAGKMFLPQVVKSARVMKKAVAYLMPYIEAEKAGGNNGKILMATVKGDVHDIGK
NIVGVVLQCNNFEVVDLGVMVAAEKILQTARDEQCDIIGLSGLITPSLDEMVHVAKEMQRQGFDIPLMIGGATTSPSY---SHPVVYVPDASRAVGVAQS
LLS
>tr|B5JXV6|B5JXV6_9GAMM Methionine synthase OX=391615 OS=gamma proteobacterium HTCC5015. GN= PE=3 SV=1
---LLQQLQE-RIVVLDGGMGTMIQGLKFSEGSNNDLLVLSQPEAIISLHEDYLRAGADIVETNSFNATPIAMADDMLSAEINLEAARLARRAADNPRFV
AGVLGPTNRTISPYRNISFDQLVEAYIESTTALVEGGCDLILIETIFDTLNAKAAVFAVKSVFELPIMISGTITSGRTLTGQTTEAFYNSLAHAEPYSIG
LNCALGPDELRQYIAELSRISDFAVSAHPNAGLPNE--MG--EYDLHPEPMAEQIREWAESGLNIVGGCCGTTPEHIEAIAKAVEGVAPRTIKP--RPVA
CRLSGLEPLTIDKDSLFINVGERTNVTGSKRFLRLIKEGDFDTALEVAQQQVEAGAQVIDINMDEGMLESKEAMVRFLNLIAGISKVPIMIDSSKWEVIE
AGLKCIQGKGIVNSISMKEEPFLEQARLIRKYGAAVIVMAFDETGQADTRERKTEICTRAYQLLEELGFPPQDIIFDPNIFAIATGIEEAVDFIEAVRDI
KQTLHAMISGGVSNVSFSFPVREAIHAVFLYHAINEGMDMGIVNAGQLAVLDDVDAEDVVLNRRDDATERLEEYRDGGSGG----KKVDLARE-WPINKR
LEHSLVKGITEFVEADTEEARQAAERPLHVIEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKKAVAYLLPYMEKEKQDESNGTVIMATVKGDVHDIGK
NIVGVVLQCNGYDVIDLGVMVPAEDILKAAREHKADVIGLSGLITPSLDEMVNVAAEMQRQGFELPLMIGGATTSPAY---EHGVIYVADASRAVGVVSR
LLG
>tr|A4BNK6|A4BNK6_9GAMM 5-methyltetrahydrofolate--homocysteine methyltransferase OX=314278 OS=Nitrococcus mobilis Nb-231. GN=NB231_10143 PE=3 SV=1
---LQEELEH-RVLLLDSATGTMIQRYRLAEGDNNDLLVCTRPDIVAEIHRSNLQAGADIIETNTFNATTPSQADATLVPEINLTAARIARKCADEPRFV
AGVLGPTSKTLSPYRNTSFTQLVEAYTEAAQGLISGGVDLLLVETIFDTLNAKACLFALDGLFKVPVMVSGTITSGRTLSGQTTEAFWNSVRHAQPFAIG
LNCALGAEDLRPYIKELSQIAECYVSTHPNAGLPNE--MG--EYEQSPHAMAQLLREFVESGVNIAGGCCGTTPEHIAAIREAIAGLPPRQRPE--RPRA
LRLSGLEPLTLGTDSLFANIGERTNVTGSARFRRLIKEDDFEAALEVGRDQVESGAQIIDVNMDEGLLDSKECMVRFLNLAAGIARVPFMVDSSKWEVIE
AGLQCIQGKAIVNSISLKEEDFIAKAGLVRRYGAAAVIMAFDEQGQADTLERRVAIAERAYRILEEVGFPPEDIILDLNIFAIATGLEEAVDFIDATREV
KTRLHVKVSGGLSNLSFSFPVRRAMHSAFLYHAIQAGMDMAIVNAGQLEVYDDIPKEDVLLNRRDDATERLEQFKGQG-KS----KEEDLERT-RSVAKR
LEHALVKGIVEYIETDTEEARTQHAQPIEVIEGPLMDGMNVVGDLFGSGKMFLPQVVKSARVMKKAVAYLLPFIEAEKNSEPNARIVMATVKGDVHDIGK
NIVGVVLQCNNFEVTDLGVMVPNEKTLAIALEQKADIVGLSGLITPSLDEMVGMAKEMERQGLDIPLLIGGATTSPQY---SGDVIYVKDASRAVGVCSK
LMS
>tr|I1YHR3|I1YHR3_METFJ 5-methyltetrahydrofolate--homocysteine methyltransferase OX=754477 OS=Methylophaga sp. (strain JAM7). GN= PE=3 SV=1
---IQQLLEQ-RILVLDGGMGTMLQSYQLSEGENNDLLSLTQPQIIRDIHRAYFESGADIVETNTFNGTAIAMADQMLVYELNKVSAQLAREIADEPRFV
AGVLGPTNRTISPFRNVHFDELVNTYLEAIRGLVDGGADLLMVETVFDTLNAKAAVFAIDTFYHLPVMISGTITSGRTLSGQTAEAFWNSLAHVQPLSIG
LNCALGAEQLRQYVEELATISTSYVSAHPNAGLPNE--FG--EYDESPETMAGHIREWAESGLNIIGGCCGTTPGHIKAIADAVSDLPPRQRPN--QH-H
CRLSGLEPLNLTPDSLFTNIGERTNVTGSLRFARLIKEGDFDTALDVARQQVENGAQVIDINMDEGMLDSQEAMVTFLNLIAAISRVPIMIDSSKWEIIE
AGLKCIQGKGIVNSISLKEDKFIEQAKLVRRYGAAVIVMAFDEQGQADTRARKLEICTRSYQILEKLHFPPEDIIFDPNIFAVATGIEEAVDFIEATRDI
KQTLHARVSGGVSNVSFSFPVREAIHAVFLYHAIKAGMDMGIVNAGQLAIYDDLPEEDVILNRRDDATDRLEEYQGGGATE----KKEDLARA-WPVAKR
LEHALVKGIADYVDEDTETARQQYDKPLEVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKKAVAYLMPYIEAAKTSKNNGRILLATVKGDVHDIGK
NIVGVVLQCNNFEIIDLGVMVPAQTILDTAKKEQVDIIGLSGLITPSLEEMAHLAKEMQRLEFALPLMIGGATTSPNY---QGPVVYVKDASRAVGVAQS
LVS
>tr|I1XMZ6|I1XMZ6_METNJ 5-methyltetrahydrofolate--homocysteine methyltransferase OX=754476 OS=Methylophaga sp. (strain JAM1). GN= PE=3 SV=1
---IRSLLEQ-KILILDGGMGTMLQSYKLSEGENNDLLSLTQPQIIRDIHRAYFEAGADIVETNTFNGTSIAMADQMLVYELNKVSAQLAREIADEPRFV
TGVLGPTNRTISPFRNVSFDQLVEAYLEAIRGLVDGGSDLLLVETVFDTLNAKAAVFAIEQYFHLPVMISGTITSGRTLSGQTAEAFWNSLSHVQPISIG
LNCALGAEQLRQYVEELSNISTSYVSAHPNAGLPNE--FG--EYDESPEAMAIHIKEWAEAGLNIIGGCCGTTPAHIKAIAEAVEGVKPRQRVN--KH-Y
CRLSGLEPLTITPESLFVNIGERTNVTGSIRFAKLIKEGDYDTALEVARQQVENGAQIIDINMDEGMLDSQDAMVTFLNLVAAISRVPIMIDSSKWEIIE
AGLKCIQGKGIVNSISLKEAKFIEQAKLVRCYGAAVIVMAFDEDGQADTRERKREICTRSYEILEKVHFPAEDIIFDPNIFAVATGIDEAVDFIEATRDI
KQSLHAMISGGVSNVSFSFPVREAIHAVFLYHTIKAGMDMGIVNAGQLAIYDDLPEEDVILNRRKDATDRLDKYKGDGSVE----KKEDLERS-LPVVKR
LEYALVKGIADFVEEDTELARHEYAKPLEVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKKAVAYLMPFIELEKVSSSNGKILMATVKGDVHDIGK
NIVGVVLQCNNFEIIDLGVMVPAQKILDAAREHNVDIIGLSGLITPSLEEMAHMAKEMERLGFEIPLMIGGATTSPNY---HGPVIYVKDASRAVGVAQN
LVS
>tr|D8K547|D8K547_NITWC Methionine synthase OX=105559 OS=Nitrosococcus watsoni (strain C-113). GN= PE=3 SV=1
---LKEQLAK-RILILDGALGTMIQSYGLTEGDNNDLLALTQPQILREIHGHYLEAGADIIETNTFNATRIAMADRMLAVEINQTAAQLAREMADEPRFV
AGVLGPTNRTISPFRNTSFDELVAAYTESIQGLIQGGADILLVETIFDTLNAKAAVYAIEKYFRFPVMISGTITSGRTLSGQTTEAFWNSLRHAEPLAFG
LNCALGPKQLRQYVEELATLADTHVAAHPNAGLPNE--FG--GYDETPEEMAQEIGEWAQAGLNIVGGCCGTTPEHIRAIREAVEKYPPRKIPQ--RPVA
CRLSGLEPSNIESDSLFVNVGERTNITGSAKFRRLIKEEDYDTALEVARQQVENGAQIIDINMDEGLLDSQKAMVRFLNLIAAISRVPVMIDSSKWEVIE
AGLKCIQGKGIVNSISLKEEPFLQQAKQVRRYGAAAVIMAFDEQGQAETTERKVGICARAYQLLEKIGFPAEDIIFDPNIFAVATGIEEGVTYIEATREI
KRTLPALVSGGVSNVSFSFKVREAIHAVFLYHAIQAGMDMGIVNAGQLAVYDEIDPEDVILNRHPEATERLEKYRGAGAAE----RKEDLARE-LPVNER
LAHALVKGITDFVEADTEEARLAAKRPLDVIEGPLMDGMNVVGDLFGSGKMFLPQVVKSARVMKKAVAYLLPFMEKEKSYKSHGKVVLATVKGDVHDIGK
NIVAVVLQCNSFEVIDLGVMVPAEKILQTAKEESCDFVGLSGLITPSLDEMVHVAKEMERQNFDLPLLIGGATTSPQY---SQPVVYVPDASRVVGVAQR
LLN
>tr|C4ZMW7|C4ZMW7_THASP Methionine synthase OX=85643 OS=Thauera sp. (strain MZ1T). GN= PE=3 SV=1
---LRQLLAE-RILILDGAMGTMIQQEKLGEGENNDLLVLTRPDVVAGIHRAYLEAGADLIETNTFNATRVSQAEGLLAYELNVEGARLVRRLCDEPRFC
AGVLGPTSRTISPYRNISFDALADDYYASAKGLLEGGADILLIETIFDTLNAKAAVFAIEKLFRWPVMISGTITSGRTLSGQTAEAFWNSLGHAQPISFG
LNCALGADQLRQYVEELSTACDTHVSAHPNAGLPNP--LSPTGYDETPEHLAGQIREWAQSGVNIVGGCCGTTPAHIAAIAEAVRGLAPRAVPV--LEKK
LRLSGLEPFNVGGDSLFVNVGERTNVTGSKAFARMILEGRFDDALAVARQQVENGAQVIDINMDEAMLDSVAAMERFCKLIATISRVPIMLDSSKWSVIE
AGLKCIQGKGVVNSISMKEAEFLRQARLARRYGAAVIVMAFDEKGQADTFRRKTEICERAYRLLAEAGFPAEDIIFDPNIFAIATGIEEAVDFINAVAWI
KENLYAKTSGGVSNVSFSFPVREAIHTVFLYHAIKAGLSMGIVNAGQLGVYDELAPEDVVMNRKPGAGEALQTVKGQA-E-----SAQDLARE-WAVEER
LSHALVKGITEFVVADTEEVRAKLEAPLAVIEGPLMAGMNVVGDLFGAGKMFLPQVVKSARVMKQAVAHLIPYIEAEKTGSSKGRIVVATVKGDVHDIGK
NIVGVVLGCNGYEVIDLGVMVPAAKILEAAKEHGAQAIGLSGLITPSLEEMAHVAAEMKRQGFSVPLLIGGATTSPHY---DQPVVYVPDASRAVGVVTA
LLS
>tr|I2JJE8|I2JJE8_9GAMM B12-dependent methionine synthase OX=1168065 OS=gamma proteobacterium BDW918. GN= PE=3 SV=1
---LITALKN-RILIIDGAMGSLIQSYKLEEGANNDLLTLTRPDVIREIHQAYLDSGADVIETNTFNSTAIAQGDDLIAEELNRVGAELAREVADAPRFV
AGVIGPTPRTISPARNTNFDELVDNYYAATRGLITGGADILMIETIFDSLNAKAAVYAVLQYFERPIMISVTFPSGRTLSGQTPTAFWNSIAHAKPLIIG
SNCGRRFSEIRPFVEELCEASDCYFSGHFNAGLPNE--FG--EYDETPEDMHGELKEFAERGLNLVGGCCGTTPAHIEAIGAAMDGIAPRPLPQ--REPI
CRLSGLEPFHIDANSLFVNVGERCNVTGSAVFKRLILENDYDAALSVARQQVENGAQVIDINMDEGMLDAEHAIVTFLNLIASICRVPIMVDSSKWDVIE
AGLKCIQGKPIVNSISMKEDEFRDRARACMKYGAAVVVMAFDEDGQADTFKRKAEICKRSYDILNEIGFPPQDIIFDPNIFAVATGIDEAVDFIEATAYI
KKELYAMVSGGVSNVSFSFPVREAIHSVFLYHAIKAGMDMGIVNASQLAIYDDLPKEDVILNRRDDSTERLDKYRGDG-SE----NKEDLTRE-WPVEKR
IEHALVKGISTYIEEDAEVARAAAVKPIDVIEGALMDGMNVVGDLFGDGKMFLPQVVKSARVMKQAVAYLNPFIEASKV-KANGRVLMATVKGDVHDIGK
NIVGVVLQCNNFEVIDLGVMVSCDKILETAKRENVDIIGLSGLITPSLDEMVHVASEMQRQGM-IPLMIGGATTSPKYQ--NDAVVYVPDASRSVAVATQ
LIS
>tr|F5T2E6|F5T2E6_9GAMM Methionine synthase I, cobalamin-binding domain containing protein OX=1026882 OS=Methylophaga aminisulfidivorans MP. GN=MAMP_01069 PE=3 SV=1
---IKSLLEQ-RILILDGGMGTLIQSYKLEEGANNDLLSLTQPQIIRDIHRAYFEAGADIVETNTFNGTSIAMADQMLVYELNKVSAELAKEVAAEPRFV
TGVLGPTNRTISPFRNVSFDELVEAYLEAIRGLVDGGADLLLVETVFDTLNAKAALFAIDQFCHIPVMISGTITSGRTLSGQTAEAFWNSLAHIQPLSIG
LNCALGAEQLRQYVEELSNVVTCHVSAHPNAGLPNE--FG--EYDESPEVMAAQIKEWAQSGLNIVGGCCGTAPAHIKAIADAVAGIKPRQPKN--LH-H
CRLSGLEPLNITPDSLFVNVGERTNVTGSARFAKLIKEGDYDTALEVARQQVENGAQIIDINMDEGMLDSKEAMVTFLNLLAAISRVPVMIDSSKWEVIE
AGLKCIQGKGIVNSISLKEEKFIEQAKLVRRYGAAVIVMAFDEVGQADTRQRKLEICRRSYEVLEKVHFPPEDIIFDPNIFAVATGIEEAVDFIEAVHDI
KQSLHALISGGVSNVSFSFPVREAIHAVFLYHAIKAGMDMGIVNAGQLAIYDDLPEEDVVQNRRDDSTDRLEKYKGEGSVA----KQEDLARE-LPVIKR
LEHALVKGIADYVEDDTEEARQQYAKPLEVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKKAVAYLMPFIEAAKTSKNNGKILMATVKGDVHDIGK
NIVGVVLQCNNFEVIDLGVMVPAQKILDTAREENVDIIGLSGLITPSLDEMVHVAKEMERLGMETPLMIGGATTSPNY---HGCSIYVKDASRAVGVAQR
LVT
>tr|A3JG88|A3JG88_9ALTE B12-dependent methionine synthase OX=270374 OS=Marinobacter sp. ELB17. GN= PE=3 SV=1
---LHQALKE-RIVILDGGMGTMIQQLKLDEGENNDLLNLTQPALMRNIHADYMDAGADIIETNTFNSSRLSQADGLIAKELNVAAARMAREIADEPRFV
AGAVGPTSRTLSPYRNVDFQALVDNYYEAVEGLVEGGCDLILIETIFDTLNAKAAIYATQQYFELPIMISGTITSGRTLSGQTTEAFWNSIAHAKPISVG
LNCALGADALRPYIEELSAKADTYVSAHPNAGLPNE--FG--EYDQTPEEMAEIIEGFARDGLNIIGGCCGSRPDHIEAIANAVAKYPPRKIAQ--PKPA
LRLSGLEPFTGDEHTLFINVGERTNVTGSKRFLRLIKEERYEEALSVARDQVENGAQIIDINMDEGLLDSKEVMVTFLNLVASICRVPIMIDSSKWEVIE
AGLRCIQGKAVVNSISLKEEEFFKRARDCMRYGAAVVVMAFDEKGQADTFKRKTEICKRSYDALS-IGFKPGDIIFDPNIFAIATGIEEAVDFINGCRWI
RANLHASISGGVSNVSFSFVVRETIHSVFLYHAIKAGLNMGIVNPGQLVIYDDIEAEDVVLNRREDSTDRLERFKGQG-KT----PEEDLARD-LPVKKR
LEHALVKGITSHIIEDTEACRQEADRPIHVIEGPLMDGMNVVGDLFGDGKMFLPQVVKSARVMKQAVAHLIPFIEAEKGGQAKGKILMATVKGDVHDIGK
NIVGVVLQCNNYEVIDMGVMVPCDKILAAAKEHNVDIIGLSGLITPSLDEMVHVAREMQRLDFHLPLMIGGATTSPHYK--NDIALYVSDASRCVNVASK
LLS
>tr|K6UGS0|K6UGS0_9PROT Methionine synthase OX=1163617 OS=Sulfuricella denitrificans skB26. GN=SCD_02290 PE=4 SV=1
---LHAQLKQ-RILILDGAMGTMIQTYKLTEGENNDLLVLTQPQIIREIHSAYLEAGADILETNTFNATSIAMADHMLVYEINVAAAKLARDAADEPRFV
AGVLGPTNRTISPFRNTSFDQLVDAYTQAIAGLVNGGSDILMVETIFDTLNAKAALFAIELYFQLPVMISGTITSGRLLSGQTAEAFWNSVSHVKPLSIG
LNCALGAQDLRQYVEELSNISNVYVSAHPNAGLPNP--LSETGYDETPEAIATDLREWAASGLNIVGGCCGTTPPHIKAIAEAVKDLPPRVIPE--IEKK
LRLSGLEALNIGEDSLFVNVGERANVTGSKMFARLIINGEYDKALEVAKAQVENGAQIIDINMDEAMLDSEAAMVKFLNLIASICKVPVMIDSSKWSVIE
AGLKCVQGKSIVNSISMKEAEFIERAKLCRRYGAAAVVMAFDEQGQADTQARKIEICARSYKLLEVVGFPAEDIIFDPNIFAVATGIEEAVDFIEATRII
KQTLYAQVSGGVSNVSFSFPVREAIHTAFLYHAIKAGMDMGIVNAGQLGVYEEIPKEDVLLNRRPDATERLESFKGAT-S-----LVEDLARE-GTVGER
LSHAMVRGITTYIVEDTEEARQQAE-PIHVIEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKLAVAHLVPFIEAEKSGKAKGKIIMATVKGDVHDIGK
NIVGVVLQCNNYDVVDLGVMVPAARILQAAIDEKADIIGLSGLITPSLEEMSHVAKEMERLGMKLPLLIGGATTSPHY---TGPVIYVKDASRAVGVCSN
LLS
>tr|G9EGS2|G9EGS2_9GAMM Methionine synthase OX=1072583 OS=Halomonas boliviensis LC1. GN=KUC_3323 PE=3 SV=1
---LTQRLAE-RILILDGGMGTMLQNAQLSEGENNDLLALTCPDVVTRIHRDYLEAGADIIETNTFNSTQLSQSDGMLVVELNRESARLAREVCDAPRYV
AGVLGPTSRTLSPKRNVTFDELRENYYEAAEALIAGGADLIMIETIFDTLNAKAAIYALEELFRLPVMISGTITSGRTLSGQTTEAFWNSVRHAQPLSVG
LNCALGAEELRPYLEELATKADTFVSAHPNAGLPNE--FG--EYDQTPEEMSEIVSEFAASGVNIIGGCCGSTPEHIRAIADSVRDMAPRVIPE--RSRA
CRLSGLEPFNIEADSLFVNVGERTNVTGSARFKRLIVEEDFTTALEVALEQVESGAQVIDINMDEGMLESKEAMERFLNLIAGIARVPIMIDSSKWEIIE
AGLKCVQGKAVVNSISLKEAAFREQATKCRRFGAAIVVMAFDEDGQADTFARKTEICQRAYRLLDEIGFPAEDIIFDPNIFAIATGIEEAVDFIEATQWI
RDNLHAMISGGVSNVSFSFPVREAIHSAFLYHAIRAGLTMGIVNAGQLAVYDDLPAEDVVLNRRSDGTERLDKYKGDG-GA----AKKEDERS-WPVNKR
IEHALVKGITVYIEDDTEQARAEAERPIEVIEGPLMDGMNVVGDLFGDGKMFLPQVVKSARVMKQAVAYLIPYIEAEKEEKAKGKIVMATVKGDVHDIGK
NIVGVVLQCNNYEVIDLGVMVPADKILQAAKEHNADIIGLSGLITPSLDEMVHVAKEMQRRGMDLPLLIGGATTSPQY---EHPVIYVTDASRAVGVAGK
LLT
>tr|Q487C0|Q487C0_COLP3 5-methyltetrahydrofolate--homocysteine S-methyltransferase OX=167879 OS=psychroerythus). GN= PE=3 SV=1
---FEQQLAK-NILILDGAMGTMIQAYKFEEAENNDMLVLTQPEIIKAIHLEYLEAGADILETNTFNATTIAMADDMYSAEINRVAAQIAREAADEPRFV
AGVLGPTNRTISPYRNVTFDELKDAYIESTLALIEGGSDIILIETIFDTLNAKAAVFAVETVFRLPVMISGTITSGRTLSGQTTEAFYNSLRHAKPVSFG
LNCALGPVELRQYVAELSRICDTAVSAHPNAGLPNA--FG--EYDFTVEDMNTHVEEWASSGLNIIGGCCGTTPEHIRGMADSVAKIKPRKVEK--REIA
CRLSGLEALTINKDSLFVNVGERTNVTGSAMFKRLIVEEDYDKAISVALQQVENGAQIIDINMDEGMLDSKTAMVRFLNLIAGIAKVPIMIDSSKWDIIE
AGLKCIQGKGIVNSISLKEENFRHQAELLRRYGAAVIVMAFDEEGQADTRKRKYEICHRAYHMLDEIGYPPEDIIFDPNIFAVATGIEEAVDFIEAVDDI
KKNLYAMISGGVSNVSFSFPVREAIHAVFLYYAIKNGMDMGIVNAGQLAIYSDLPAEDVIQNKDDGATERLQEFHGKAGQA----SKTDLTRE-LPINAR
LSHALVKGINEFIIEDTEEARLASEKPLDVIEGPLMDGMNTVGDLFGAGEMFLPQVVKSARVMKQAVAYLNPYIEEGKEISTNGKVLLATVKGDVHDIGK
NIVGVVLQCNNYEIIDLGVMVSCDDILRVAKEENVDIIGLSGLITPSLDEMVYVAKEMKRTGLKLPLLIGGATTSPQY---DEPVVYVSNASRAVSVVSN
LLS
>tr|E1STX6|E1STX6_FERBD Methionine synthase (B12-dependent) OX=550540 OS=Ferrimonas balearica (strain DSM 9799 / CCM 4581 / PAT). GN= PE=3 SV=1
---LEQQLAQ-RILILDGAMGTMIQGYKLDEGENNDLLSLTQPDIIRAIHTAYLEAGADIIETNTFNSTTIAMADDMLSKEINFESARLARAAADDPRYV
AGVLGPTNRTISPFRNVHFDDLVAAYTESTEALLDGGADLILVETVFDTLNAKAALFAIDSVFRWPVMISGTITSGRTLTGQTTEAFYNSLRHIKPIAIG
LNCALGPKELVPYISELNRISECAVSAHPNAGLPNE--MG--GYDETPAQMAAIIGQWAADGLNIVGGCCGTTPEHIRAIAEAVRPHAPRTPPN--DNVS
TRLSGLEPCNFDADALFINVGERTNVTGSARFLRLIKENDYETALEVARQQVENGAQIIDINMDEGMLDAEAAMVKFLNLIASISKVPIMIDSSKWEVIE
AGLKCIQGKGVVNSISLKEAAFLHQAKLIRRYGAAAVVMAFDETGQADTYQRKVEICTRAYQVLEKAGFAPEDIIFDPNIFAIATGIEEAVDFIEACRTI
RDTLHARLSGGVSNVSFSFPVREAIHAVFLYHAIRNGLSMGIVNAGQLAIYDDIPKEDVVLNRRSDGTERLEEYRGDGQAE----DPKDAERS-WPVNKR
LEHALVKGITEFIDEDTEAARQAATRPLDVIEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKKAVAYLNPYIEAEKEGQSNGKVLMATVKGDVHDIGK
NIVAVVLQCNGYEVIDLGVMVPVEKIIEVAKAEKVDVIGMSGLITPSLDEMIHNVKEFKKAGLTCPAIIGGATTSEHY---EHGAIYVPDASRTVPVVAK
LIG
>tr|I2J2W4|I2J2W4_HAEPA Methionine synthase OX=1095745 OS=Haemophilus parainfluenzae HK262. GN= PE=3 SV=1
---LKKSLAE-RILILDGAMGTMIQKYKLTEGENNDLLTLTQPLLISAIHEKYLQAGADIIETNTFSSTTIAQADDLIAYELNFAGAKLARLAADKPRFV
AGVLGPTNRTISPFRNITFMELVDAYAEAIKGLIEGGADLIMIETIFDTLNAKAAIFAIETVFELPIMISGTITSGRTLSGQTTEAFYNSLRHAKPLTFG
LNCALGPKELRQYVEQLSKISETYVSVHPNAGLPNA--FG--GYDLGAEEMAAHLKEWAESGVNIVGGCCGTTPEHIKAFADAMQGIAPRKLPE--IKTA
MRLSGLEPLNIDDESLFVNVGERNNVTGSAKFKRLIKEDKFAEAIEIAIDQVENGAQVIDVNMDEALLDGKKCMTRFLNIMATAAKVPVMIDSSKWEVIE
AGLQSVQGKPIVNSISLKEEIFIKHAKLVRKYGAAVVVMAFDEVGQADTEDRKVEICSRAYDILNQVGFPPEDIIFDPNIFAIGTGIEEGVDFINATGRI
KRSLHAKISGGVSNVSFSFVMREAIHAVFLYHAIKQGMDMGIVNAGQLAIYDDLDPEDAVLNRNPDATEKLEKYRNQGESA----VDSVAERT-WPVEER
LKHALVKGITTHIIEDTEEARQKLPTPLEVIEGPLMAGMDVVGDLFGDGKMFLPQVVKSARVMKQSVAYLEPFINATKKGSSNGKVVIATVKGDVHDIGK
NIVSVVMQCNNFEVIDLGVMVPADKIIQTAIDEKADIIALSGLITPSLDEMEYFLGEMTRLGLNLPVMIGGATTSPKY---KHGVFYTSNASRAVTVCAT
LMN
>tr|H7EQ85|H7EQ85_PSEST B12-dependent methionine synthase OX=32042 OS=Pseudomonas stutzeri ATCC 14405 = CCUG 16156. GN= PE=3 SV=1
---LQQALKE-RILILDGGMGTMIQSYKLEEGANNDLLLLSRPDVIQAIEKAYLDAGADILETNTFNATQVSQADGMLVYELNVEGARLAREVADAPRFV
AGVLGPTSRTISPYRNVTFDLLVENYVEATRGLIEGGADLILIETIFDTLNAKAAIFAVQQVFELPIMISGTITSGRTLSGQTTEAFWNSVRHAKPISVG
LNCALGAKDLRPYLEELSSKADTFVSAHPNAGLPNA--FG--EYDESPAEMAAVVEEFAVSGLNIIGGCCGTTPAHIQAIAEAVSKYPPRVIPD--IPKA
CRLSGLEPFTIDRSSLFVNVGERTNITGSAKFARLIREENYTEALEVALQQVEAGAQVIDINMDEGMLDSKAAMVTFLNLIAGISRVPIMIDSSKWEVIE
AGLKCIQGKGIVNSISMKEEQFKHHAHLCKRYGAAVVVMAFDEAGQADTAARKREICQRSYDILNEVGFPPEDIIFDPNIFAIATGIEEAVDFIEACAFI
RDNLYALTSGGVSNVSFSFPVREAIHSVFLFHAIKAGLTMGIVNAGQLEIYDEIPKEDVVLNRSANGTEGLDKYKGDG-VK----EAETEERG-LPVGKR
LEHALVKGITAFIVEDTEEYRQQCARPIEVIEGPLMSGMNVVGDLFGAGKMFLPQVVKSARVMKQAVAHLIPFIEAEKDKEAKGKILMATVKGDVHDIGK
NIVGVVLGCNGYDVVDMGVMVPAEKILQTAIAEKCDIIGLSGLITPSLDEMVHVAKEMQRQGFSLPLMIGGATTSPQYH--NDAVVYVTDASRAVGVATT
LLS
>tr|E1VKB4|E1VKB4_9GAMM Methionine synthase I (5-mathyltetrahydrofolate-homocysteine mathyltransferase) vitamin-B12 dependent OX=83406 OS=gamma proteobacterium HdN1. GN= PE=3 SV=1
---IHQAIQE-RILILDGAMGTMIQQRKLSEGENNDLLCLTRPDVIRQIHLDYLEAGADILETNTFNAQRISQADHLIVYELNREGARLAREAADAPRFV
AGVLGPTNRTMSRARSVTFDDLVENYTEATHGLMDGGADIILIETIFDTLNAKAAVFAVRRVFTLPIMISGTIVAGRTLSGQTVEAFYNSLRHAKPLSMG
FNCALGAEQLRPYVDELSTKAECFVSAHPNAGLPNE--FG--EYDQSAEQMAAIVRDFAASGLNIVGGCCGTTPEHIRAIAEAVASYPPRPRPE--LPKA
MRLAGMEAFNIDEHSLFVNVGERTNVTGSARFRRLIREEKYEEALEVAREQVENGAQVIDINMDEGMLDSQAAMMRFLNMLSMISRVPIMVDSSRWEIIE
EGLKRIQGKPIVNSISLKEAEFIERARLCMEYGAAAVVMAFDETGQADTLERKQQITKRSYDCLS-IGFPPEDIIFDPNAFAIATGIEEGVDFINACAYI
KQNLYAKSSGGISNVSFSFTVREAIHAVLLYHAIKAGLTMGIVNAGQLAIYEDIPAEDVVLNRREDATDRMEQYRGGG-QK----SKEDLSRE-LPVEKR
LEYALVKGITTYAVEDTEIARQKANRPIEVIEGPLMDAMNVVGDLFGSGKMFLPQVVKSARVMKTAVAHLIPFIEAEKGNESKGKILLATVKGDVHDIGK
NIVGVVLQCNNYEVIDLGVMVPSEKILETAKNEKVDMIGLSGLITPSLDEMVHVAKEMQRTGSDLPLLIGGATTSPQYK--NEAVVYVPDASRAVGVVSQ
LLN
>tr|C5BJB9|C5BJB9_TERTT Methionine synthase OX=377629 OS=Teredinibacter turnerae (strain ATCC 39867 / T7901). GN= PE=3 SV=1
---LQEALNQ-RILILDGAMGTMIQRHKLQEGENNDILSLTRPDIIAGIHREYLEAGADIIETNTFNATRLSQSDDTIAFELNKASATLAREAAD-PRFV
AGILGPTSRTISPARNVTFDQLVENYTEATHGLIEGGADILMIETIFDTLNAKAAVFAVSSVFKLPIMISGTITSGRTLSGQTTEAFYNSLAHAEPLSIG
LNCALGASELEPYVKELARVANCRVSAHPNAGLPNE--FG--EYDQSAAEMAEIVIKFAENGLNVVGGCCGTTPAHIAAIADAVASLPPREINP--PPVS
CRLAGLEPFNITADSLFVNVGERCNVTGSARFKRLILEEDYATALDVAQQQVTDGAQIIDINMDEGMLDAEAAIVRFLNLIAGIARVPIMVDSSKWEVIE
AGLKCIQGKPIVNSISLKEAEFVEKARLCRRYGAAVIVMAFDEQGQADTQARKIEICSRSYRILEELGFPPEDIIFDPNIFAVATGIDEAVDFIEATRWI
RQNLHAGVSGGVSNVSFSFPVREAIHSVFLYHAIRAGMNMGIVNAGQLAIYDDLPEEAVISNTSADATEALEKYRGDG-QQ----QSKEDERT-ADVNKR
LEHALVKGITSYIEADTEEARLQSSRPLDVIEGPLMDGMNVVGELFGSGKMFLPQVVKSARVMKQAVAWLQPYIEAEKEGRSNGKILMATVKGDVHDIGK
NIVGVVLQCNNFEVVDLGVMVPGEKILETAKREGCDIIGLSGLITPSLDEMVAVAREMETQGIDLPLMIGGATTSPQFH--LNQAVYVPDASRAVGVATR
LLS
>tr|H0Q064|H0Q064_9RHOO B12-dependent methionine synthase OX=748247 OS=Azoarcus sp. KH32C. GN= PE=3 SV=1
---IRDLLAR-RILILDGAMGTMIQQHKLGEGENNDLLVLTRPEVVAGIHRAYLEAGADIIETNTFNGTRVSQAEGLVAYEINVAGARLVRELCDEPRYC
AGVLGPTSRTISPFRNISFDALVDDYYDSARGLLEGGADLLLIETIFDTLNAKAAVFAVEKLFRVPVMISGTITSGRTLSGQTAEAFWNSLAHARPISFG
LNCALGAKELRQYVEDLSNVCDTHVSAHPNAGLPNP--LAPTGYDETPEQLATAIREWAAAGVNIVGGCCGTTPAHIAAIAEAVADIAPRKVPE--VEKK
LRLSGLEPFNVGADSLFVNVGERTNVTGSKAFARMILEGRFDDALAVARQQVENGAQVIDINMDEAMLDSLAAMERFLKLIASISRVPIMLDSSKWSVME
AGLKCIQGKGVVNSISMKEAEFLRQARLCRQYGAAVIVMAFDEKGQADTYARKTEICKRAYDLL--IGFPPEDIIFDPNIFAIATGIEEAVDFINAVAWI
KANLFAKTSGGVSNVSFSFPVREAIHTVFLYHAIKAGLSMGIVNAGMLGVYDDLDPEDVVLNRNAGAGEALQGVKGKA-N-----AGPDLARA-LSVEER
LSHALVKGITEFVVADTEEVRAKLEAPLAVIEGPLMAGMSVVGDLFGAGKMFLPQVVKSARVMKQAVAHLIPFIEAEKTGASKGRIVMATVKGDVHDIGK
NIVGVVLGCNGYEVIDLGVMVPAEKILNAAREHGAQAIGLSGLITPSLEEMSHVAAEMQRQGFDVPLLIGGATTSPHY---GQPVVYVPDASRAVGVVTA
LLS
>tr|D4F072|D4F072_EDWTA Methionine synthase OX=500638 OS=Edwardsiella tarda ATCC 23685. GN=EDWATA_00095 PE=3 SV=1
---LRRRLEK-RILLLDGGMGTMIQRYGLSEADNNDLLVLTRPDIISAIHYAYLEAGADILETNTFNATRIAMADRMLAPEINYQAACLARACADEPRFV
AGILGPTNRTISPCRNITFDQLVDAYRESARALIEGGVDLLMIETVFDTLNAKAAVYALECEFTLPVMISGTITSGRTLSGQTTEAFYNSLRHARPLSFG
LNCALGPEDLRQYVAELSRIAECYVSAHPNAGLPNA--FG--EYDLSPQAMAQQIAEWAQAGLNIVGGCCGTTPEHIAAISQAVRDIAPRTRPL--PARA
CRLAGLEPLTIDEQTLFVNVGERTNVTGSARFKRLIKENNYDEALEVARQQVESGAQIIDINMDEGMLDAEAAMVRFLNLIAGIARVPLMIDSSRWSVIE
AGLKCIQGKGIVNSLSLKEAAFLEHARQVRRYGAALVVMAFDEQGQADSRERKVAICRRAYQLLERLDFPPEDIIFDPNIFAVATGIEEALDFIDACAEI
KAQLHALISGGVSNVSFSFTVREAIHAVFLYHAIRHGMDMGIVNAGQLAIYDSLPDEAVILNQSPDATEHLERYRGV-PGE----GSGRAERD-WPVAQR
LEYALVKGIGEFVEQDTEEARQQVDRPIAVIEGPLMAGMNRVGDLFGDGKMFLPQVVKSARVMKQAVAYLSPFIEASKRGSSAGKVLLATVKGDVHDIGK
NIVGVVLQCNNYEIIDLGVMVPAERILRVAREEQVDIIGLSGLITPSLDEMVNVASEMERQGFTLPLLIGGATTSPAY---SGPTVYVQNASRTVGVVAA
LLS
>tr|A0YB18|A0YB18_9GAMM Methionine synthase OX=247633 OS=marine gamma proteobacterium HTCC2143. GN=GP2143_04840 PE=3 SV=1
---LKELISQ-RILIIDGAMGSMIQTYGLQEGDNNDILSITKPSIIEEIHNAYLDAGADIIETNSFNATRVAQGDQLFSYEINVASAKIARAAADRPRFV
AGVLGPTPRTISPARNTSFDQLSDDYYQSTKGLIEGDVDIILIETIFDTLNAKAAIFAVKRCFELPIMITVTFPSGRILSGQSPEGFWNSIAHAKPLIVG
TNCGRRFKEIRPFIEELANVADCYFSGHFNAGLPNA--FG--EYDETPEDMFDDLKGFADRGLNLVGGCCGTTPEHIAEIAKIADLCSPREIPL--KPIA
CRLSGLEPFTISKESLFVNVGERCNVTGSAKFKRLIIEEDFDTALDVAREQVENGAQIIDINMDEGMLDAQSAMVKFLKLIASISRVPIMVDSSKWEIIE
AGLKCIQGKPIVNSISLKENEFLEKAQLCLDYGAAVVVMAFDEKGQADTLERKMAICQRSYNLLQQLDFPPQDIIFDPNIFAVATGIEEAVDFIEATRFI
KNTLHALVSGGVSNVSFSFPVREAIHSVFLYYAIKAGLDMGIVNAGQLAIYDDLPQEDIVLNQRDDSTERLADYVGDG-AK----QADNLERE-LPVEKR
IEHALVKGITNFIIEDTEQARLIADRPISVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAYLQPFIEDEKE-KANGKIIMATVKGDVHDIGK
NIVGVVLQCNNYEVIDLGVMVSCSEILRAAKEQNADIIGLSGLITPSLDEMVHVAKEMTREGF-IPLMIGGATTSPQYD--KAPIVYVPDASRSVSVAST
LLN
>tr|C6C8P4|C6C8P4_DICDC Methionine synthase OX=579405 OS=Dickeya dadantii (strain Ech703). GN= PE=3 SV=1
---LQQQLDQ-RIMILDGGMGTMIQGYRLQEGANNDLLVLTKPDVIAAIHHDYLAAGADILETNTFNATRIAMADDMLSAEINTVAARLARTCADEPRYV
AGVLGPTNRTISPYRNVSFDQLVDAYRESTRALIEGGVDLILIETIFDTLNAKAAVYAVECEFTLPVMISGTITSGRTLSGQTTEAFYNSLRHARPLSFG
LNCALGPDELRQYVAELARISECYVSAHPNAGLPNA--FG--EYDLDAREMAQQVGEWAQSGLNIIGGCCGTTPAHIAAMAQAVDGVPPRKLPQ--TPVA
CRLSGLEPLNIGADTLFVNVGERTNVTGSAKFKRLIKEEKYNEALDVARQQVENGAQIIDINMDEGMLDAEAAMVRFLNLIAGIARVPIMIDSSKWDVVE
AGLKCIQGKGIVNSISMKEDIFIEHAKKVRRYGAAVVVMAFDEVGQADTRERKIDICRRAYRILEEVGFPPEDIIFDPNIFAVATGIEEAVDFIGACDDI
KTQLHALISGGVSNVSFSFPVREAIHAVFLYYAIRNGMDMGIVNAGQLAIYDDLPAEDVVLNRRTDGTERLEKYRGS-KSD----DDSEAERG-WPVKKR
LEYALVKGITEFIEADTEEARAQAARPIEVIEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKQAVAYLEPFIQASKAGSSAGKILLATVKGDVHDIGK
NIVGVVLQCNNYEIIDLGVMVPSDKILKTAREEKVDIIGLSGLITPSLDEMVNVAKEMERQGFTLPLLIGGATTSQNY---SGPTVYVQNASRSVSVVSS
LLS
>tr|A1WZ06|A1WZ06_HALHL Methionine synthase (B12-dependent) OX=349124 OS=halophila (strain DSM 244 / SL1)). GN= PE=3 SV=1
---IRDQLAQ-RILILDCGMGTEIQKYPLEEGENNDLLVLTRPDIIRDITRQNLDAGVDIVETNTFNSQVLSQADGTLVDELNIEAAKLARAVCDEPRFV
AGTMGPTGKTISPHRDITFDQLFEAYAQQARGLLEGGADLILIETVFDTLNAKAAIYALEEVFRLPVMISGTITSGRTLSGQTAAAFWNSVRHARPISIG
LNCALGAEDLRPHLQELSKIADTHISTHPNAGLPNE--FG--EYDQSPEEMAKIVRTFAEEGINIIGGCCGTSPAHIAAIREQVKDFAPRQVPD--LAPD
VRLSGLEPCNIGKDSLFVNIGERANVTGSARFRRLIKEGDYETALEVAKEQVENGAQIIDINMDEGMLDSKDAMIDFLNLVGSISRVPIMIDSSKWDIIE
EGLKRIQGKGLVNSISLKEEAFLQQARKLKRYGAAAVVMCFDEKGQADTYERRLEIAERAYNALND-GFEPADIVFDLNIFAVATGIEEAVDFIEATRWV
KENLHAKVSGGLSNLSFSFPVREAMHSVFLYHAIKAGLDMAIVNAGQIEVYDEIDKEDVILNRHEDATDRLERYKGQG-KK----KEEDLARE-EPVEKR
LEHALIKGITDYIDVDVEEARQKHDRPIQVIEGPLMDGMNTVGDLFGEGKMFLPQVVKSARVMKQAVSHLLPYIEAEKDDEPAGRVLIATVKGDVHDIGK
NIVAVVLQCNNFEVHDIGVMVPTETILQKAKEVKADIIGLSGLITPSLDEMIGVAQEMERQGFTCPLLIGGATTSPNY---SAPSIYVKDASRAVGVASK
LVS
>tr|J4R1V1|J4R1V1_ACIRA Methionine synthase OX=903900 OS=Acinetobacter radioresistens WC-A-157. GN= PE=3 SV=1
---LKELLAK-RILIIDGAMGTMIQRHRLEEGENNDLLVLTQPQIIQSIHEAYLDAGADIIETNSFNGTRVSMSDHMLVREINREAARLAKAACEKPRFV
AGVLGPTSRTISPFRNITFDALKENYIEATHALIEGGADIILIETVFDTLNCKAAIFAVKEVFELPLMISGTITSGRTLTGQTAEAFWNSVRHGDLLSIG
FNCALGADAMRPHVKTVADVADVFVSAHPNAGLPNA--FG--GYDETPEETAAFLKEFAESGINITGGCCGTTPDHIRAIYNAVKDIAPRQIPI--KP-A
CRLSGLEPFNIYDESLFVNVGERTNVTGSKKFARLIREENYAEALDVARQQVEGGAQIIDINMDEGMLDSQNAMVTFLNLIASISRVPIMIDSSKWEIIE
AGLKCVQGKAVVNSISLKEDEFVEKARLCRQYGAAVIVMAFDEKGQADTVERKKEICKRSYDVLNEVGFPSEDIIFDPNVFAVATGIEEGVDFIEATGWI
KQNLNAMISGGISNVSFSFPVREAIHAVFLYYAIKQGLTMGIVNAGQLAIYDDIPAEDVVMNRNSGATEKLEKYRGQGTQR----EAENLERN-EPVEKR
LEYALVKGITAFINEDTEEARLKSARPLDVIEGPLMAGMNVVGDLFGSGKMFLPQVVKSARVMKQAVAWLNPYIEAEKAGEAKGKILMATVKGDVHDIGK
NIVGVVLGCNGYDIVDLGVMVPAEKILQTAIDEKVDIIGLSGLITPSLDEMVFVAKEMQRKGFKIPLMIGGATTSPQYS--NDAVIYVADASRAVGVATS
LLS
>tr|Q65TU4|Q65TU4_MANSM MetH protein OX=221988 OS=Mannheimia succiniciproducens (strain MBEL55E). GN= PE=3 SV=1
---LKASLAQ-RILILDGAMGTMIQQYKLSEGENNDLLSLTQPLLIQAIHEKYLQAGADIIETNTFSSTSIAQADDLIAYELNFAGAKLARIAADKPRFV
AGVLGPTNRTISPFRNITFMQLAEAYGEATRGLIAGGADIIMLETIFDTLNAKAAVFAIEQVFRLPVMISGTITSGRTLSGQTTEAFYNSLRHAKPLSFG
LNCALGPKELRQYVEQLSKISECYVSAHPNAGLPNA--FG--GYDLGAEEMAAQLKEWAESGLNIVGGCCGTTPEHIKAFAEAMQGVKPRPLPQ--IKTA
MRLSGLEPLSIDDDSLFVNVGERNNVTGSAKFKRLIKEEKFGEAIEIAIDQVENGAQVIDVNMDEALLDSQKCMTRFLNIMATAAKVPVMIDSSKWEVIE
AGLQSIQGKGIVNSISLKEEKFIRQAKLIRRYGAAAVVMAFDEKGQADTEARKVEICTRAYDILNQAGFPPEDIIFDPNIFAIGTGIEEGVDFINATGRI
KQTLYAKVSGGVSNVSFSFPMREAIHAVFLYHAIKQGMDMGIVNAGQLAIYDDLDPEDAVLNRRPDATDRLEKYRNQDTGE----DNGVAERS-WSVEER
LKHALVKGITHFIIEDTEEARQKFSLPLEVIEGPLMAGMDVVGDLFGDGKMFLPQVVKSARVMKQSVAYLEPFINATKKGSSNGKVVIATVKGDVHDIGK
NIVSVVLQCNNFEVIDLGVMVPADKIIETAIAEKADIIGLSGLITPSLDEMEYFLGEMNRLNLNIPVLIGGATTSPKY---KYEVIYTTNASRAVTVCAA
LMN
>tr|I2BDY8|I2BDY8_SHIBC Methionine synthase OX=630626 OS=105725 / CDC 9005-74) (Escherichia blattae). GN= PE=3 SV=1
---LHQQLAQ-RILVLDGGMGTMIQGYRLDEGENNDLLVLTQPEIITAIHNAYFEAGADIIETNTFNSTTIAMADQMLSAEINYAAARLARECADAPRYV
AGVLGPTNRTISPYRNITFDQLVAAYRESTRALVEGGVDLILIETVFDTLNAKAAIFAVETEFSLPVMISGTITSGRTLSGQTTEAFYNSLRHAGALSFG
LNCALGPDELRQYVAEMSRIAECYVSAHPNAGLPNA--FG--EYDLDADTMAAQVKEWAESGLNIVGGCCGTTPAHIAAMSRAVAGVAPRKRPV--LPVA
CRLSGLEPLNIGEDSLFVNVGERTNVTGSAKFKRLIKEEKYSEALDVARQQVENGAQIIDINMDEGMLDAEAAMVRFLNLIAGIARVPIMIDSSKWEVIE
KGLKCIQGKGIVNSISMKEEAFTEHAKRVRRYGAAMVVMAFDEQGQADTRERKREICTRAYNILREVGFPPEDIIFDPNIFAVATGIEEAVDFIGACEDI
KRDLHALISGGVSNVSFSFPVREAIHAVFLYYAIRNGMDMGIVNAGQLAIYDDLPGEDVILNRRDDGTERLEKYRGS-KTD----EAALAERN-WEVKKR
LEYSLVKGITEFIEQDTEEARQQADRPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAYLEPFIEASKKGQSNGKMVIATVKGDVHDIGK
NIVGVVLQCNNYEIIDLGVMVPAEKILKTAREENADLIGLSGLITPSLDEMVHVAKEMERQGFTIPLLIGGATTSQNY---SGPTVYVQNASRTVGVVSS
LLS
>tr|C7RCM5|C7RCM5_KANKD Methionine synthase OX=523791 OS=Kangiella koreensis (strain DSM 16069 / KCTC 12182 / SW-125). GN= PE=3 SV=1
---LQESLKQ-RILLLDGAMGTMIQQYELTEGENNDLLSLSQPQIISDIHKAYLEAGSDIIETNTFNATRVAMADGMLSADINRESARLARAVADQPRFV
AGVIGPTNRTISPFRNIYFDELADAYYESTHALIEGGADIILIETVFDTLNAKAAIFAVKKYFDYPIMLSGTITSGRTLTGQTTEAFYNSIRHANPISVG
LNCALGPKDLRAYIEELSRISEFAVSAHPNAGLPNE--FG--GYDETPDDMSREMSEWIEKGINIIGGCCGTTPEHIARFNDMIAGAKPRTKFN--QEPR
CRLSGLEALNLDAKSLFVNVGERTNVTGSAKFLRLIKEDDFETAIEVALEQVENGAQVIDINMDEGMLDSKAAMQRFLNLIASISRVPIMLDSSKWDIIE
AGLKCVQGKGIVNSISLKEPQFLEQAHLAQRYGAAVIVMAFDEDGQADTFERKTEICRRAYDLLKELNFDPQDIIFDPNIFAIATGIEEAVDFIEATRWI
KQNLGARVSGGVSNVSFSFTVREAIHAVFLYHAIRAGMDMGIVNAGQLEVYSAIPEENVVLNRSPEATEKLEQYRGSGEVK----EKETQERQ-WPVNKR
LEHSLVKGITEFIDDDVEEARQQAERPLHVIEGPLMDGMNVVGDLFGSGQMFLPQVVKSARVMKKAVAYLFPYMEEEKLKKPKGKIVLATVKGDVHDIGK
NIVGVVLQCNGYEVINLGVMVACDKILDTAIEQNCDIVGLSGLITPSLEEMVHVAKEMQRRGLDLPLLIGGATTSPHY---EHPAMYVMDASRVVGVVNK
LLG
>tr|A1SR72|A1SR72_PSYIN Methionine synthase (B12-dependent) OX=357804 OS=Psychromonas ingrahamii (strain 37). GN= PE=3 SV=1
---IKAQLEK-HILLIDGAMGTMIQSYKFEEGENNDLLVLSQPRVIADIHREYLDAGADILETNTFNATTIAMADQMLSAEINREAARLARQEADQPRFV
AGVLGPTNRTISPFRNVSFDELVEAYTESTRALIEGGCDLILIETIFDTLNAKAAVFAVSGVFKLPVMISGTITSGRTLTGQTTEAFYNSLRHIEPISFG
LNCALGPEELRQYVQEISKISETYVSAHPNAGLPNA--FG--EYDLEADEMAAHIKEWAESGLNLVGGCCGTTPAHIKAMADAVAGVKPRALPE--IEIA
CRLSGLEALTIRKDSLFQNVGERTNVTGSARFKRLIMDELYDQALEVALHQVTAGANIIDINMDEAMLDSLYAMKRFLNLCASISRVPIMIDSSKWEILE
EGMKCVQGKGIVNSISMKEDNFIAQAKLIRRYGFAVIVMAFDEDGQADTRARKFDICKRSYDILNQVGFPPEDIIFDPNIFAVATGISDAVDFIEAVKDI
KTNLHVMISGGVSNVSFSFPVREAIHAVFLYHCIQNGMDMGIVNAAQLAIYDDIPKEAIILNTSPDATDNLEKYRDSGKVD----DGKSLERN-LPVNER
IAHSLVKGITEFIVEDTEEARVNAEMPIDVIEGPLMDGMNIVGDLFGDGKMFLPQVVKSARVMKQAVAYLNPYIEETKVGATNGKIVMATVKGDVHDIGK
NIVGVILQCNNYEIIDLGVMVPTEKIIKTAIAEKADIIGLSGLITPSLDEMVYVAKEMQRQGLKLPLLIGGATTSQNY---DQPVVYVSNASRAVGVCQK
LLN
>tr|A0KFD9|A0KFD9_AERHH Methionine synthase OX=380703 OS=Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / NCIB 9240). GN= PE=3 SV=1
---LEACLKE-RILIIDGAMGTMIQGYKLGEGANNDLLVLTRPAVIREIHEQYCAAGADILETNTFNATRIAMADEMFSAEINCEAARLARAVADEPRFV
AGVLGPTNRTISPKRNVTYDQLVAAYTESTHALIEGGADIILIETIFDTLNAKAAAFAVEGVFSLPVMISGTITSGRTLSGQTTEAFYHSLRHVKPVSFG
LNCALGPDELRQYVEELSRISETHVSAHPNAGLPNA--FG--EYDLDAVEMAEHIREWAASGLNLVGGCCGTTPTHIRAMADAVAGIKPRALPE--LPVA
CRLSGLEPLIITPESMFVNVGERTNVTGSAKFKRLIKEGLYDEALDVAKQQVESGAQIIDINMDEGMLDAEAAMVRFLNLIAGIARVPVMIDSSKWEVLE
AGLKCVQGKPVVNSISMKEEKFIQQARLLRRYGAAVIVMAFDEVGQADTRARKFEICQRAYRILDRVGFPPEDIIFDPNIFAVATGIDEAVDFIDAVKDI
KQNLHAMISGGVSNVSFSFPVREAIHAVFLYHAIQNGMDMGIVNAGQLAIYEDIPSEAVVLNLNPDATEALERYRGGGQTE----DPRDQARS-WPVGKR
LEHALVKGITDFIEEDTEEARSKAEKPLHVIEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKRAVAYLQPYIEAEKGGSSNGKIVMATVKGDVHDIGK
NIVGVVLQCNNYEIVDLGVMVSCETILKTAREVNADIIGLSGLITPSLDEMVHVAKEMERQGFKLPLLIGGATTSQNY---SEPVVYVSNASRAVGVAQS
LLS
>tr|J7KUX1|J7KUX1_PECCC B12-dependent methionine synthase OX=1218933 OS=Pectobacterium carotovorum subsp. carotovorum PCC21. GN=PCC21_037650 PE=3 SV=1
---LRRQLAQ-RIMVLDGGMGTMIQGYRLQEGENNDLLVLTRPQVISEIHDAYLEAGADILETNTFNATTIAMADDMLSAEINTVAAQLARASADKPRYV
AGVLGPTNRTISPYRNVSFDQLVEAYRESTRALIAGGVDLIMIETIFDTLNAKAASFAVESEFELPVMISGTITSGRTLSGQTTEAFYNSLRHSRPLSFG
LNCALGPDELRQYVAELSRISECYVSAHPNAGLPNA--FG--EYDLDPADMAKHIGEWARSGLNIVGGCCGSTPAHIAAMAKVVEGVPPRKLPE--IPVA
CRLSGLEPLTIDANTLFVNVGERTNVTGSARFKRLIKEEKYNEALDVARQQVESGAQIIDINMDEGMLDAEAAMVRFLNLIAGIARVPIMIDSSRWEVVE
KGLQCIQGKGIVNSISMKEEAFVHHAKLVRRYGAAVVVMAFDEVGQADTRARKIEICRRAYRILEEVGFPPEDIIFDPNIFAVATGIDEAVDFIEACADI
KAQLHAMISGGVSNVSFSFLVREAIHAVFLYHAIRNGMDMGIVNAGQLAIYDDLPAEDVILNRRSDATERMEKYRGS-KTE----DEGQAERG-WDVKKR
LEYSLVKGITEFIELDTEEARQQAARPIEVIEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKQAVAYLEPYIEASKKGSSAGKILLATVKGDVHDIGK
NIVGVVLQCNNYEIIDLGVMVPTDKILKTAREEKVDIIGLSGLITPSLDEMVNVAKEMERQGFTLPLLIGGATTSQNY---SGPTVYVQNASRSVGVVSA
LLS
>tr|H3NXP7|H3NXP7_9GAMM Methionine synthase (B12-dependent) OX=745014 OS=gamma proteobacterium HIMB55. GN=OMB55_00003990 PE=3 SV=1
---LKKSLSE-RIVLLDGGMGTMIQQAGLSEGDNNDLLTLTQPSLIAQIHRQYLAAGSDIIETNTFNTNAPSMGDGMLVARLNKEAAQLARAVCDKPKLV
AGVLGPTNRTISPFRNITFDELVDTYSTATRALMDGGADLILVETIFDTLNAKAALYAIDVVSLIEIMISGTITSGRTLSGQTTESFWYSVRHANPISVG
LNCALGPAELRPFLRELADVADTHVSAHPNAGLPNQ--FG--EYDLTTTEMADIVAEYSASGVNIVGGCCGTTPDHIAEIAARVKGHQPKPLSV--KPRV
MRLSGLEPFVADDAKGFINIGERTNVTGSARFKKLILEDDLETALEVARQQVENGAQIIDINMDEGLLDSEGAMVRYLNLLASISRVPIMIDSSKWDVLK
AGMKCVQGKGVVNSISLKEASFIEQAREIRRYGFAVVVMAFDETGQADTRDRKVEICKRSYEILREVGFPPEDIIFDPNIFAVATGIEEAKDFIEACGKI
REVCHSMTSGGLSNVSFSFPVREAMHSVFLYHAIRNGLNMAIVNAGQLAIYADIDPEDVVLNRRSDGTDRLPAF-ANSEEV----VESLAERS-KPVKER
LEYALVNGIDQYAVEDTEEARLNSARPLDVIEGPLMDGMNTVGDLFGAGKMFLPQVVKSARVMKKAVAHLVPFIEAEKGESEQGTIIMATVKGDVHDIGK
NIVGVVLQCNNYKVIDLGVMVPTQAIWDAAKEHNADIIGLSGLITPSLDEMVTVAAEMERQGFDIPLLIGGATTSPSY---SGDTVYVKDASRAVGVAAK
LLG
>tr|F5RGW6|F5RGW6_9RHOO Methionine synthase OX=1000565 OS=Methyloversatilis universalis FAM5. GN=METUNv1_03558 PE=3 SV=1
---LKALMAR-RILILDGAMGTMVQKHRLVEGTNNDLLLLTRPDVIRGIHAAYLEAGADIIETNTFNATKISQAEGLIVHELNVEGARIAREACDEPRFV
AGVLGPTSRTLSPFRNVTFDQLVEDYVAAARGLTEGGADLLLVETIFDTLNAKAALFALEQFFRWPIMISGTITSGRTLSGQTAEAFWNSLRHSNPISFG
FNCALGPKDMRQHVEELAHLADTHVSAHPNAGLPNA--FG--EYDETPADMVNHLREWAQSGLNIVGGCCGTTPDHIAAFAKAMDGMPPRAVPE--IERK
LRLSGLEAFNVGADALFVNVGERTNVTGSRAFAKMILESRFDDALAVARQQVENGAQVIDINMDEAMLDSVAAMERFLKLIASISRVPIMLDSSKWSVIE
AGLKCIQGKGVINSISMKEAEFLRQATLARRYGAAVIVMAFDEKGQADTYQRKTEICQRAYTLLEQVGFPPEDIIFDPNIFAIATGIAEAVDYIEAVGWI
HRNLYAKTSGGVSNVSFSFPVREAIHTVFLYHAIRNGLSMGIVNAGQLGVYEDIPQEDVVLNRHPGAGDALITVKGQA-E-----STQDLARE-WPVDKR
LEHALVKGITEFVVEDTEEVRARLEAPLAVIEGPLMAGMNHVGDLFGAGKMFLPQVVKSARVMKQAVAHLQPYIEASKVGETKGRVIMATVKGDVHDIGK
NIVGVVLGCNGYEVIDLGVMVACERILQAARDHKADIIGLSGLITPSLEEMSHVASEMTREGFDIPLLIGGATTSPNY---AHPVVYVPDASRAVGVATS
LLS
>tr|F3L143|F3L143_9GAMM 5-methyltetrahydrofolate--homocysteine methyltransferase OX=876044 OS=gamma proteobacterium IMCC3088. GN=IMCC3088_1135 PE=3 SV=1
---LEQALQE-RILIIDGAMGTMIQGYKLAEGSNNDLLCLTRPDLIIDIHKAFLEAGADLIETNSFNSTAVAQSDGLLADELNRAAARLAREAADHPRYV
AGILGPTPRTISPARNIDYDSLVQDYRVAAVALLEEGVDIIMIETIFDTLNAKAALFAVEAAFKRPIMLSVTFPSGRILSGQTAEAFWNSIAHAKPLIVG
TNCGRRFKEVRPYVEALANAADCYFSGHFNAGLPNA--FG--EYDETPEDMFADLQDFAQRGLNLVGGCCGTRPEHIKAIAEAVGSAKPRELPK--LEPG
CYLSGLEPFNITAESLFVNVGERCNVTGSAAFKRLIINEQYEDALAVARTQVEDGAQIIDINMDEGMLDAQKAMVTFLNLAASISRVPFMLDSSRWDAIE
AGLKCVQGKCIVNSISLKEAEFLEKARLCQRFGAAVVVMAFDEDGQADTFERKTEICQRSYTLLEELGFNPNDIIFDPNIFAVATGIDEAVDFIEATRWI
KQNLGAMVSGGVSNVSFSFPVREAIHSVFLYHAIKAGLDMGIVNAGQLAVYDELPAEDVILNRRDDATERLEEYRGDG-AK----KVEDLERT-WPVAKR
IEHALVKGINTYVIEDAEEARQAFSRPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAYLQPFIEAEKE-GSNGKILMATVKGDVHDIGK
NIVGVVLQCNNFEVIDLGVMVHCETILQAAREHQVDIIGLSGLITPSLDEMAHVASEMQRQGF-IPLMIGGATTSPQYQ--NDVAVYVPDASRSVSVATA
LLG
>tr|E5YJ87|E5YJ87_9ENTR Methionine synthase OX=469613 OS=Enterobacteriaceae bacterium 9_2_54FAA. GN=HMPREF0864_02598 PE=3 SV=1
---LRHQLSQ-RILVLDGGMGTMIQGYRLTEGDNNDLLVLTKPDIISAIHYDYLEAGADILETNTFNSTRIAMADHMLSAEINYEAARLARACADEPRYV
AGVLGPTNRTISPFRNISFDQLVEAYRESTRALVEGGVDLIMIETIFDTLNAKAAIYAVETEFELPVMISGTITSGRTLSGQTTEAFYNSLRHVKPLTFG
LNCALGPDELRQYVAELSRIAECFVTAHPNAGLPNA--FG--EYDLGPKEMAEHIAEWAQAGLNIVGGCCGTTPAHIAAISRAVDGVKPRALPD--IPVA
CRLAGLEPLTIDANTLFVNVGERTNVTGSAKFKRLIKEDKYAEALEVALQQVESGAQIIDINMDEGMLDAEAAMVRFLNLIAGIARVPIMIDSSKWEVIE
KGLKCIQGKGIVNSISMKEDKFIEHARKVRRYGAAMVVMAFDEVGQADTRARKIEICRRAYKLLETVGFPPEDIIFDPNIFAVATGIEEAVDFIEACADI
KAELHALISGGVSNVSFSFPVREAIHAVFLYYAIRNGMDMGIVNAGQLAIYDDLPTEDVILNRREDGTERLEKYRGS-KSD----DDSQAERS-WPVKKR
LEYSLVKGITEFIEADTEEARLEAERPIEVIEGPLMDGMNVVGDLFGDGKMFLPQVVKSARVMKQAVAYLEPFIEASKKGTSAGKVLLATVKGDVHDIGK
NIVGVVLQCNNYEIIDLGVMVPCDKILKTAREQNVDIIGLSGLITPSLDEMVYVAKEMERQGFDLPLLIGGATTSQNY---SGPTTYVSNASRTVGVVAA
LLS
>tr|D2YUG0|D2YUG0_VIBMI 5-methyltetrahydrofolate--homocysteine methyltransferase OX=671076 OS=Vibrio mimicus VM573. GN= PE=3 SV=1
---LEQQLKQ-RILLIDGGMGTMIQSYKLQEGANNDLLVLTQPQIIKDIHSAYLEAGADILETNTFNSTTIAMADDMLSDEINFAAAKLAREVADEPRYV
AGVLGPTNRTLSPFRNVTFDQLVQAYSESTRALIKGGSDLILIETIFDTLNAKACAFAVDSVFSLPVMISGTITSGRTLSGQTTEAFYNALRHVRPISFG
LNCALGPDELRQYVEELSRISECYVSAHPNAGLPNA--FG--EYDLSAEDMAEHIAEWAQAGLNLVGGCCGTTPEHIAAMAKAVDGVKPRALPE--LKVE
CRLSGLEPLNIGPETLFVNVGERTNVTGSARFKRLIKEEQYDEALDVAREQVENGAQIIDINMDEGMLDAEACMVRFLNLCASISKVPVMVDSSKWEVIE
AGLKCIQGKGIVNSISLKEEKFIAQAKLVRRYGAAVIVMAFDEVGQADTRERKLEICSRAYHILDEVGFPPEDIIFDPNIFAVATGIDEALDFINAVADI
KRELHAMISGGVSNVSFSFYVREAIHAVFLYHCFKHGMDMGIVNAGQLEIYDNVPLEDVILNRRNDGTERLEAYRENSKEE----DASALERT-WPVAKR
LEHALVKGITEFIVQDTEEARQQASKPLEVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAYLEPFINAQKGSTSNGKILLATVKGDVHDIGK
NIVGVVLQCNNFEIIDLGVCVPCEQILKVAREENVDIIGLSGLITPSLDEMVHVAKEMERQGFELPLLIGGATTSQNY---HAPVVYVNNASRAVGVCTS
LLS
>tr|A4BC32|A4BC32_9GAMM 5-methyltetrahydrofolate--homocysteine methyltransferase OX=314283 OS=Reinekea blandensis MED297. GN=MED297_01810 PE=3 SV=1
---LHQAIRE-RILILDGAMGSLIQSYQLEEGENNDLLTLTRPDVIEAIYTAYLEAGSDIIETNTFNSTAVSQDDGMLAYELNREGAALARRACDAPRWV
TGVIGPTSKTLSPYRAITFEALVEDYKTATRGLIDGGADLLLIETIFDTLNAKAAIFAIHSVFELPIMISGTITSGRTLSGQTTEAFYYSVKHAKPLTVG
LNCALGADELRPYVETLSSIADCYVSVHPNAGLPNE--FG--EYDESPEEMTSVVDEFAASGVNIIGGCCGTTPKHIELINAAMQKHSPRQPAA--DPHR
MALSGLEPFVLTDELNFVNVGERTNVTGSAKFRRLIKEELYDEALDVAREQVENGAQIIDVNMDEGMLDSADAMTTFLNLIASIARVPIMVDSSKWDVIE
AGLRCVQGKAIVNSISLKEANFLHQAKLCQRYGAAVVIMAFDETGQADTRERKIEICQRSYDLLA-HGFPPEDIIFDPNIFAVATGIDEALDFIEATDHI
RRNMYASVSGGVSNVSFSFPVREAIHSVFLYHASKVGMNMGIVNAGQLVIYDDIPDEDVILNRRNDATDRLEKYRGDG-TE----VKEDLERS-LPVNKR
IEHALVKGITAHIIDDTEEARQQATAPIDVIEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKQAVAHLIPFIEAEKADKPKGKVLMATVKGDVHDIGK
NIVGVVLACNNFDVIDLGVMVPAEKILKVAREENVDVIGLSGLITPSLDEMVHIAREMQRQDFHLPLMIGGATTSPQYH--NDATIYVTDASRAVSVVQS
LLN
>tr|G8QHN5|G8QHN5_AZOSU 5-methyltetrahydrofolate--homocysteine methyltransferase OX=640081 OS=suillum). GN= PE=3 SV=1
---LSALLQQ-RLLILDGAMGTMIQRHGLTEGTNNDLLLLTRPEVIRGIHAEYLAAGADILETNTFNATKVSQADKLIVYELNVAGARLAREVCDEPRFV
AGVLGPTSRTISPYRNVTFDELVENYLEAIRGLTDGGADILLVETVFDTLNAKAALFAIETFFRWPVMISGTITSGRTLSGQTAEAFWNSLNHIRPLSFG
LNCALGAKELRQYVEELSRVCDCFVSAHPNAGLPNA--FG--GYDETPEQLAEEIADWARHGVNIVGGCCGTSPDHIAAIAKMVAGIAPRAIPA--IEPQ
LRLSGLEPFNVGPDSLYVNVGERTNVTGSKAFARMILEGRYDDALAVARQQVENGAQVIDINMDEAMLDSVAAMEKFLKLIASISRVPIMLDSSKWEVIE
TGLKCIQGKGIVNSISMKEAKFLEQAKLARRYGAAVIVMAFDEKGQADTYARKTEICKRAYDLL--IGFPAQDIIFDPNIFAIATGIEEAVDFINATRWI
RENLHAQISGGVSNVSFSFPVREAIHTVFLYHAIQAGMTMGIVNAGMLGVYDDLEPEDVVLNRHPGAGEALQTVKGKA-D-----TGPDLTRT-LPVEKR
LEHALVKGITEFVVADTEEVRAALAAPLAVIEGPLMNGMNTVGDLFGAGKMFLPQVVKSARVMKQAVAHLIPYIEEEKTGSSKGKIVIATVKGDVHDIGK
NIVGVVLGCNGYDVVDLGVMVPTEKILHAAKEHGAQAIGLSGLITPSLEEMSHVASEMQRQGFNVPLLIGGATTSPNY---QAPVVYVPDASRAVGVVTS
LLS
>tr|E8VT14|E8VT14_VIBVM 5-methyltetrahydrofolate-homocysteine methyltransferase OX=914127 OS=Vibrio vulnificus (strain MO6-24/O). GN= PE=3 SV=1
---IEAQLKQ-RILLIDGGMGTMIQGYKLQEGENNDLLVLTQPQLIKEIHHAYLEAGADILETNTFNATTIAMADDMLSEEINFAAAKLAREAADEPRYV
AGVLGPTNRTISPYRNVSFDELVAAYSESTRALIRGGSDLILIETIFDTLNAKACAFAVESVFALPVMISGTITSGRTLSGQTTEAFYNSLRHVRPISFG
LNCALGPDELRPYVEELSRISETFVSTHPNAGLPNA--FG--EYDLSPEEMAEHVKEWAQSGLNLIGGCCGTTPEHIRHMAMAVEGVSPRVLPE--IPVA
CRLSGLEPLTIAKDTLFVNVGERTNVTGSARFKRLIKEELYDEALDVAREQVENGAQIIDINMDEGMLDAEACMVRFLNLCASISKVPIMVDSSKWEVIE
AGLKCIQGKGIVNSISLKEEKFVEQAKLIRRYGAAVIVMAFDEVGQADTRERKLEICTKAYRILDEVGFPPEDVIFDPNIFAVATGIDEAVDFIEAVADI
KRDLHAMISGGVSNVSFSFYVREAIHAVFLYHCFKNGMDMGIVNAGQLEIYDNVPEEDVVLNRRDDATERLEEYRENAKQE----DASALERT-WSVEKR
LEHALVKGITEFIVEDTEEARLNATKPLEVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAHLEPFINASKAGSSNGKILLATVKGDVHDIGK
NIVGVVLQCNNYEIIDLGVMVPCEQILKVAKEQQVDIIGLSGLITPSLDEMVHVAKEMERLGFDLPLLIGGATTSQNY---SHPVVYVNNASRAVGVCTS
LLS
>tr|B6ELR4|B6ELR4_ALISL Methionine synthase OX=316275 OS=LFI1238)). GN= PE=3 SV=1
---IEKQLLE-RILLIDGGMGTMIQEYKFEEGENNDLLVLSNPSVIRDIHLAYLEAGADILETNTFNATTIAMADDMLSAEINFEAAKLARKAADEPRYV
AGVLGPTNRTLSPFRNVTFDGLVKAYSESTRALIKGGSDLILIETIFDTLNAKACSFAVESVFTLPVMISGTITSGRTLSGQTTEAFYNALRHVKPISFG
LNCALGPDELREYVGELSRISECSVSAHPNAGLPNA--FG--EYDLSPEEMAEHVAEWARSGLNLIGGCCGTTPEHIRQMAAAVEGVKPRVLPD--IPVA
CRLSGLEPLTISKESLFVNVGERTNVTGSARFKRLIKEELYDEALSVAREQVENGAQIIDINMDEGMLESEACMVRFLNLCASISKVPVMVDSSKWEVIE
AGLKCIQGKGIVNSISLKEEKFVEQAKLVRRYGAAVIVMAFDEKGQADTRERKIEICTNAYNILNEVGFPPEDIIFDPNIFAIATGIDEAVDFIEAVADI
KRTLHAMISGGVSNVSFSFYVREAIQAVFLYHCFKHGMDMGIVNAGQLEIYDNVPEEDVVLNRRDDSTERLTAYLEKAKVE----DKSALERT-WTVEKR
LEHSLVKGITDFIVDDTEEARVNSERPIHVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAHLEPFINATKVGSTNGKILLATVKGDVHDIGK
NIVGVVLQCNNYEIIDLGVMVSCEKILKVAKEENVDIIGLSGLITPSLDEMVHVAKEMERQGFTVPLLIGGATTSQNY---SQPVVYVNNASRAVGVCTS
LLS
>tr|A5CWS5|A5CWS5_VESOH 5-methyltetrahydrofolate--homocysteine methyltransferase OX=412965 OS=Vesicomyosocius okutanii subsp. Calyptogena okutanii (strain HA). GN= PE=3 SV=1
---LKSLLNK-RILVLDGAMGTMIQQHKLTEGDNNDLLSLTQPQIIKNIHKDYLKVGADIIETNTFNATRTSMSDKMLAYEINLKSAKIARQAADEPRFV
AGVIGPTSRTLSPFRNITFDELVDVYIESTRGLIKGGVDIILIETIFDTLNAKAAIFAIEQVFELPIMISGTITSGRTLSGQMTEAFYNSLRHAKPISIG
LNCALGPDLLRQYVAEMSRVADTYVSAHPNAGLPNE--FG--EYDLNALTMSEQVSEWARSGVNILGGCCGSTPDHIRAIADSINRIPPRKIPT--IKPE
CRLSALEAFNIGNDSLFVNIGERANITGSAKFKRLILNQEYEKALDICRTQVEEGAQMIDINMDEGMLDGKTAMIRFINLIASIAKVPLIVDSSKWEIIE
AGLKCTQGKPIVNSISLKETKFIQYARLCKRYGAAIIVMAFDESGQADTQARKIEICTKAYYILNNVNFPPEDIIFDPNIFAIATGIEEGIDFIEATRAI
KKNLYAKISGGVSNVSFSFTVREAIHSVFLYHTVKAGMTMGIVNAGQLMVYNDIDPEDVVLNINKQAGERLLKFS-NTQKN----NKQNLERT-WAVERR
LEHALVKGITTYINKDTQEAFDKLGRPILVIEGPLMSGMNVVGDLFSAGKMFLPQVVKSARVMKKSVAYLDPFLENEKNTSSQGKILMATVKGDVHDIGK
NIVSVVLSCNNYKIIDLGVMVPTETILETARKENVDIIGLSGLITPSLDEMVFVAKEMTRQGLKLPLMIGGATTSPEY---DHGVFYVKDASKSVGVATA
LLS
>tr|L0MM33|L0MM33_SERMA Methionine synthase (B12-dependent) OX=1249634 OS=Serratia marcescens FGI94. GN=D781_4212 PE=4 SV=1
---LRRQLEQ-RILVLDGGMGTMIQSYKLEEGANNDLLVLTQPDIISAIHHGYLEAGADILETNTFNATPIAMADHMLSAEINREAARLARRCADEPRYV
AGVLGPTNRTISPFRNISFSQLVEAYRESTRALVEGGVDLIMIETIFDTLNAKAAAFAVESEFTLPIMISGTITSGRTLSGQTTEAFYNSLRHVKPLSFG
LNCALGPDELRQYVAELSRICEGYVSAHPNAGLPNA--FG--EYDLDAQEMASQVGEWARSGLNIIGGCCGTTPAHIAAMAKAVEGVAPRPLPQ--LPVA
CRLSGLEPLNIDADTLFVNVGERTNVTGSARFKRLIKEDKYAEALEVALQQVESGAQIIDINMDEGMLDAEAAMVRFLNLIAGIARVPIMIDSSKWEVIE
KGLQCIQGKGIVNSISMKEEAFIHHARLVRRYGAAVVVMAFDEVGQADTRERKFAICRRAYQILEKVGFPPEDIIFDPNIFAVATGIYEAVDFIEACGDI
KKHLHAMISGGVSNVSFSFPVREAIHAVFLYHAIRNGMDMGIVNAGQLAIYDDLSDEDVILNRRDDGTERLEKYRGS-KDK----DADQAERG-WPVVKR
LEYALVKGITEFIEQDTEEARQQAERPIEVIEGPLMAGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAYLEPYIQASKQGTTAGKVLLATVKGDVHDIGK
NIVGVVLQCNNYEIIDLGVMVPTEKILKTAREENVDIIGLSGLITPSLDEMVNVAKEMERQGFTLPLLIGGATTSQNY---SGPTTYVQNASRTVGVVAA
LLS
>tr|K6B073|K6B073_MORMO 5-methyltetrahydrofolate--homocysteine methyltransferase OX=1239989 OS=Morganella morganii SC01. GN=C790_1719 PE=4 SV=1
---LKKSLNQ-RILILDGAMGTMIQRYALNEGENNDLLSITQPDIIREIHHAYLEAGADIIETNSFNSTVISMADQMLSDEINEAAAKLARECADEPRYV
AGILGPTNRTISPYRNVSYDALVEAYRSSVRALVRGGADIIMIETIFDTLNAKAAIYAVETEFKLPVMLSGTITSGRTLTGQTTEAFCNSMRHIRPISFG
LNCALGPAELRQYVAELSRIADCYVSTHPNAGLPNA--FG--GYDLDAANMAGYISEWAQSGLNIVGGCCGTTPDHIRAIAQAVADIPPRVIPD--RPVA
CRLAGLEPLTIDENSLFVNVGERTNITGSARFKRLIKEGNYQEALDIARNQVENGAQIIDINMDEGMLDSQAAMVRFLNMISGIARVPIMIDSSKWEVIE
AGLKCIQGKGIVNSISLKEAAFIDHAKKVLRYGAAVIVMAFDETGQADTRQRKTEICQRAYRILEQVGFPPEDIIFDPNIFAVATGIPEAVDFIEACKDI
KATLHALISGGVSNVSFSFPVREAIHAVFLYYAIRNGMDMGIVNAGQLAIYDDLPAEDVILNRREDATDRLEEYRGS-K-G----ENDLAERG-WDVEKR
LEYALVKGITEFIVEDTEAARLRADSPIEVIEGPLMNGMNVVGDLFSEGKMFLPQVVKSARVMKQAVAYLEPYIQAAKSGSSAGKVLLATVKGDVHDIGK
NIVGVVLQCNNYEIIDLGVMVPCETILRTAIEEKVDIIGLSGLITPSLDEMVHVAKEMERQGFSLPLLIGGATTSPNY---SGPVTYVQNASRTVGVVAA
LLS
>tr|G3ITR9|G3ITR9_9GAMM Methionine synthase OX=697282 OS=Methylobacter tundripaludum SV96. GN=Mettu_1405 PE=3 SV=1
---LKQQLSQ-RILFLDGAMGTMIQSYKLEEGENNDLLSLTQPDIIKAIHSAYFEVGSDIVETNTFNATSIAMADKMLAYEMNVAAARVAREAADEPRFV
AGVLGPTNRTMSPFRNIFFDDLVLAYTEATQGLIDGGADIILIETVFDTLNAKAAIFAVEQYFKLPVMISGTITSGRTLSGQTVAAFWNSLKHVEPISFG
FNCALGATELRQYIAELSSIADTHISAHPNAGLPNE--FG--EYDETPEAMAEELADWAKNGLNIIGGCCGTSPANIKAIVEAVQQYSPRMVPE--IPKQ
CRLSGLEPLNIGPDSLFVNVGERTNVTGSAAFKRLVIEGDFEAALDVAEQQVENGAQIIDINMDEGMLESKEAMVRFLMLIASIAKVPIMLDSSKWEILE
AGLKCIQGKGVVNSISLKEAAFIEHAKLVRRYGAAVIVMAFDEEGQADTKARKVEICQRAYKILEQVGFPPEDIIFDPNIFAVATGIDEGLDFIEATQEI
KRTLYALISGGVSNVSFSFPVREAIHAVFLYHAIQAGMDMGIVNAGQLAIYEDIPREDVILNRHDSGTDKLDKYRGDGSSAG---KEQDLERS-WPVTKR
LEHALVKGITDYIDEDTEQARLEAERPLHVIEGALMDGMNVVGDLFGAGKMFLPQVVKSARVMKKAVAYLMPFMEADKERQTNGKILMATVKGDVHDIGK
NIVGVVLQCNNYDVIDMGVMVPAENILQTARLENVDIIGLSGLITPSLDEMVHVAKEMQRQGFTIPLMIGGATTSPNY---DGPIVYVTDASRGVGVASN
LLS
>tr|C2LM17|C2LM17_PROMI 5-methyltetrahydrofolate--homocysteine methyltransferase OX=525369 OS=Proteus mirabilis ATCC 29906. GN= PE=3 SV=1
---LTQALAK-RILVLDGAMGTMIQQYQLAEGENNDLLVLTQPQIITEIHNAYFEAGADIVETNTFNATSIAMADQMLCAELNEEAAKLARACADKPRYV
AGVLGPTNRTISPFRNISFDTLVMAYREAICGLIKGGVDLIMVETIFDTLNAKAAIFAIKCEFELPVMISGTITSGRTLTGQTTEAFYHSLRHADALSFG
LNCALGPKELRQYIQTLSQISETYVSAHPNAGLPNA--FG--GYDLDANEMAEQIKEWAQAGLNIVGGCCGTTPAHIQAIAQAVDGIAPRTLPV--IKKA
CRLSGLEPLVIDDNSLFVNVGERTNVTGSAKFKRLIKEGNYQEALDVARQQVENGAQIIDINMDEGMLDAIEAMTRFLNLIAGIAKVPIMIDSSKWQVIE
EGLKCIQGKGIVNSISMKEALFIEHAKLVRKYGAAVVVMAFDEIGQADTRERKIEICQRAYHLLEKAGFPPEDIIFDPNIFAVATGIAEAVDFIEVCADI
KSQLYALISGGVSNVSFSFPVREAIHSVFLYYAVKNGMDMGIVNAGQLAIYDSLPDEDVILNRHAESTDNLERYRGT-KSE----EQHLAQRQ-WEVEKR
LEYALVKGITEFIIEDTEACRQQASSPIEVIEGPLMNGMNTVGDLFGEGKMFLPQVVKSARVMKQAVAYLEPYIQATKAGSSAGKVLLATVKGDVHDIGK
NIVGVVLQCNNYEIIDLGVMVPCDKILQTAIDEHVDIIGLSGLITPSLDEMVNVAKEMERRGFSLPLMIGGATTSPNY---SHPTVYVQNASRTVGVVAA
LLS
>tr|D9SI53|D9SI53_GALCS Methionine synthase OX=395494 OS=capsiferriformans (strain ES-2)). GN= PE=3 SV=1
---IEDIIQQ-RILILDGAMGTMIQRYKLNEGENNDLLVLTKPEVIRAIHSEYLAAGADIVETNTFGANATTLKAGMLNYELNVAGARLAREACDAPRFV
AGVLGPTDKTISPARNISFDQLVADYSDATRGLMDGGADTILIETIFDTLNAKAAIFAVQSVFRLPIMISGTITSGRTLTGQVTEAFYNSLAHAQPLSIG
LNCALGAEELRQYVAELSRVANCYVSAHPNAGLPNP--LAETGYDDTPENMAGHIKEWAASGLNIIGGCCGTSPAFIKAIAETVQGIAPRKIPE--NPVE
CRLSGLEPFNISDSSLFVNVGERANVTGSAKFKRLILEGKYDEALEVAKQQVETGAQVIDVNMDEAMLDGEAAMVRFLNLIASISKVPLMIDSSKWSIIE
AGLKCVQGKSIVNSISLKEENFIKYATLVRKYGAAAVVMAFDEAGQADTYARKIEICKRSYDILNKVGFPPEDIIFDPNIFAIATGIEEAVDFIEACKWI
RANLYAKISGGVSNVSFSFPVREAIHTVFLYHAIGAGMNMGIVNAGQLGVYEEIPREDVVLNRHPDAGEKLESVKGGG-E-----IIEDLERK-GTVQER
LTHALVRGITTFIVEDTEEARLAAK-PVEVIEDSLMSGMNVVGDLFGAGKMFLPQVVKSARVMKQAVAHLIPYIEAEKSGSTKGKILMATVKGDVHDIGK
NIVTVVLQCNNFEVVNMGVMVPCQQILDAAREHKVDVIGLSGLITPSLEEMAHVAKEMERQGFKIPLLIGGATTSPNYP--SGTVIYVTDASRAVGVCSN
LLS
>tr|H8GNL7|H8GNL7_METAL 5-methyltetrahydrofolate--homocysteine methyltransferase OX=686340 OS=Methylomicrobium album BG8. GN=Metal_1844 PE=3 SV=1
---LKQLLSQ-KILFLDGAMGTMIQSYKLEEGANNDLLSLTQPAIIKAIHCAYLEAGADIIETNTFNSTRVAMADRMLVYEINVESARLARQACDDPRFV
AGVLGPTNRTMSPFRNISFDELVEAYTEATRGLIDGGADIILIETVFDTLNAKAAAFAVDAYFKLPVMISGTITSGRTLSGQTVAAFWHSLKHIEPISFG
FNCALGAKELRQHIDELSTIADTHVSAHPNAGLPNE--FG--EYDESPEMMAQEIADWAKQGLNIIGGCCGTTPAHIKAIVEAVSPYPPRAIPD--IPKA
CRLSGLEATAIGPDSLFVNVGERTNVTGSAVFKRLIVAGDYEAALDVARQQVENGAQVIDINMDEGMLESKEAMVRFLMLLAAIAKVPIMLDSSKWEILE
AGLKCIQGKGIVNSISLKEAKFIEHAKLVRRYGAAVIVMAFDEVGQADTQARKVEICTRAYRILEQLGFPPEDIIFDPNIFAIATGIEEGLDFIEATHEI
KATLHALISGGVSNVSFSFPVREAIHAVFLYHAIQAGMDMGIVNAGQLAIYEDIPAEDVVLNRHPHATEKLERYRGDGSGAV---KPEELERS-WPVNKR
LEHALVKGIADFIDEDTEAARLQADKPLHVIEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKKAVAYLMPFMEDDQERQSNGKILMATVKGDVHDIGK
NIVGVVLQCNNYEVIDLGVMVPAETILQTARKEKVDIIGLSGLITPSLDEMVHLAKEMQRQGFTIPLLIGGATTSPNY---EGATVYVPDASRGVGVAGS
LLS
>tr|Q6LM78|Q6LM78_PHOPR Putative cobalamin-dependent methionine synthase OX=74109 OS=Photobacterium profundum (Photobacterium sp. (strain SS9)). GN= PE=3 SV=1
---LQKRLAE-NILIIDGGMGTMIQGYKLDEGENNDLLVLTQPQLIKDIHNEYLEAGADILETNTFNATTIAMADDMLSAEINFEAAKLARQAADEPRFV
AGVLGPTNRTISPFRNVTFDQLVEAYSESTRALIAGGVDLILVETIFDTLNAKACTFAVETVFVLPIMISGTITSGRTLSGQTTEAFYNSLRHVKPISFG
LNCALGPDELRQYVDELSRISESAVSAHPNAGLPNA--FG--EYDLSPEDMAEHIEEWAKSGLNLVGGCCGTTPEHIRLMEQVTRNVKPRQLPD--IPIA
CRLSGLEPLTISADTLFVNVGERTNVTGSARFKRLIKDELYDEALEVARQQVEAGAQIIDINMDEGMLDAEAAMVRFLNLCATISKVPIMVDSSKWEILE
AGLKCIQGKPIVNSISMKEEKFIAQAKLIRRYGAAVIVMAFDEEGQADTRERKIEICTNAYHILNEVGFPPEDIIFDPNIFAVATGIEEAVDFIEAVGDI
KRTLYAMVSGGVSNVSFSFPIREAIHAVFLYYCFKNGMDMGIVNAGQLAIYDDLTDEDVVLNRRDDSTERLEKYRGSGVEE----DRTLQERG-WPVEKR
LSHALVKGITEFIVEDTEEARTNASKPLEVIEGPLMAGMNIVGDLFSEGKMFLPQVVKSARVMKQAVAHLEPYINAEKAGYTNGKILLATVKGDVHDIGK
NIVGVVLQCNNYEIIDLGVMVSCEKILKVAKEKNVDIIGLSGLITPSLDEMVHVAKEMERQGFELPLLIGGATTSENY---HGPVVYVSNASRAVGVCSA
LLS
>tr|G4SZ71|G4SZ71_META2 Methionine synthase (5-methyltetrahydrofolate--homocysteine methyltransferase) (Methionine synthase, vitamin-B12 dependent) (MS) OX=1091494 OS=B-2133 / 20Z). GN= PE=3 SV=1
---FKKRLSQ-SILFLDGAMGTMIQSYKLEEGKNNDLLSLTQPDIIKAIHCAYLDVGCDIIETNTFNATQIAMADQMLAYEINLESARIARQAADEPRFV
AGILGPTNRTMSPFRNIDFDTLVDAYTEAMRGLIDGGVDIILIETVFDTLNAKAAIFAVDQYFKLPVMISGTITSGRTLSGQTVAAFWNSLSHIEPISFG
FNCALGAKELRQHIEELSSIADTHVSAHPNAGLPNE--FG--EYDESPEDMALELADWAANGLNIIGGCCGTSPEHIKAIVEAVKQYPPRVVPV--IEKQ
CRLAGLEPMNIGSDSLFVNVGERTNVTGSAKFKRLVVEGDFETALEVAKDQVENGAQIIDINMDEGMLESKEAMVRFLSLIAAIAKVPIMLDSSKWDIIE
AGLKCIQGKGIVNSISLKEEAFIQHAKLIRRYGAAAIVMAFDEQGQADTRDRKVEICSRAYRILEQLNFPAEDIIFDPNIFAIATGIDEGMDFIEATREI
KRTLHALISGGVSNVSFSFPVREAIHAVFLYHAIKAGMDMGIVNAGQLAIYEDIPLEDVVLNRNDHATERLEKYRGDGTAA----KPEELERS-WPVTKR
LEHALVKGIADFIDEDTEQARQEAEKPLHVIEGALMDGMNVVGDLFGAGKMFLPQVVKSARVMKKAVAYLMPFMEAEQEMQTNGKILMATVKGDVHDIGK
NIVGVVLQCNNFQVIDLGVMVPAEKILQTARDEKVDIIGLSGLITPSLDEMVHMAKEMERQGFDIPLMIGGATTSPNY---HGPVVYVADASRSVGVASH
LVS
>tr|G0A5L1|G0A5L1_METMM Methionine synthase OX=857087 OS=Methylomonas methanica (strain MC09). GN= PE=3 SV=1
---LNQQLKQ-RILYLDGAMGTMIQSYKLGEGTNNDLLSLTQPDIIKAIHKAYLEAGSDIIETNTFNATKIAMADHMLAYEINVASARLAKQAAEEPRFV
AGVLGPTNRTMSPFRNITFDDLVDAYSEATQGLIDGGADIILIETVFDTLNAKAAIFAVENTFKLPVMISGTITSGRTLSGQTAAAFWTSLKHVKPISIG
FNCALGAQELRQYIEELSNIADTYVSAHPNAGLPNE--FG--EYDETPEQMAAELADWAASGLNIIGGCCGTSPDTIRAIVEAVGKYPPRQIPE--LEKR
CHLAGLEAMSIGPETLFVNVGERTNVTGSAIFKKMIIEERYEDALEVAKQQVENGAQIIDINMDEGMLDSKAAMVRFLNLLAAIAKVPIMLDSSKWEILE
AGLKCIQGKGVVNSISIKEEAFIKHAKLVRRYGAAVIVMAFDEQGQADTMQRKIEICTRAYKILEQIGFPPEDIIFDPNIFAVATGIEEGVDFIEATRII
KQTLHALISGGVSNVSFSFPVREAIHAVFLYHAIQAGMDMGIVNAGQLAIYADIPSEDVILNRTPEGTEKLEKYRGTGVA-----KQETLERE-WPVSKR
LEHALVKGIADYIDEDTEQALQEAEKPLHVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKKAVAYLMPFMDAEVVRQTNGKVLMATVKGDVHDIGK
NIVAVVLQCNNYEVIDLGVMVPADTILKTAREEKVDVIGLSGLITPSLDEMVHVAKEMQRQGFTIPLMIGGATTSPNY---QHPTIYVTDASRSVGVVSA
LLS
>tr|Q0F311|Q0F311_9PROT 5-methyltetrahydrofolate--homocysteine methyltransferase OX=314345 OS=Mariprofundus ferrooxydans PV-1. GN=SPV1_04898 PE=3 SV=1
---LKQQLDR-RILILDGAMGTMIQRHQLEEGENNDLLNLTQPDIIQGIHQAYLDAGADILETNTFNSNTPSMADHMLVYELNVAGAALARKAADAPRFV
AGVLGPTSRTISPFRNVHFDELVTTYKDATRGLIDGGADIILIETVFDTLNAKAAVFAVQSYFELPIMISGTITSGRTLSGQTATAFYNSLAHAKPISIG
LNCALGAGELRQYIEELSGTVACRINAHPNAGLPNA--FG--GYDETAEDMAAQIREWAESGLNIIGGCCGTGPAHIRAMAEAVEGIAPRPLPR--GELQ
CRLSGLEPLHIDESSLFVNVGERANVTGSAVFKRLIMAGDYNTALNICREQVENGAQIIDINMDEAMLDGEKAMVTFLNLIASISRVPIMLDSSKWSIIE
AGLKCIQGKGVVNSISLKEEAFIHHARLLRRYGAAAVVMAFDEAGQADTFARKTEICARSYKILEVCDFPPEDIIFDPNIFAIATGIEEAVDFIEATGWI
KQHLYAMVSGGVSNVSFSFPVREAIHSVFLYHAIKQGMDMGIVNAGQLAVYDDLSEEDVVLNRREDSTERLEKYRGDGIEV----KKADDERK-LPVAER
LAHALVKGIDTFVDEDTEEARLAFATPIEVIEGPLMDGMNVVGDLFGDGKMFLPQVVKSARVMKKAVAWLMPYIEAGKNS-SNGKVLMATVKGDVHDIGK
NIVGVVLQCNNFEVIDLGVMVPAKTILDEAVKHDVDIIGLSGLITPSLDEMVHIAKEMTRLGLTIPIMIGGATTSPEY---AHPLVWVKDASRAVGVAQN
LIS
>tr|Q1ZNV8|Q1ZNV8_PHOAS B12-dependent methionine synthase OX=314292 OS=S14 / CCUG 15956)). GN= PE=3 SV=1
---LHKRLEE-QILIIDGGMGTMIQGYKLEEGQNNDLLVLTQPQLIKDIHLAYLEAGADILETNTFNATTIAMADDMLSAEINYEAARLARLAADEPRFV
AGVLGPTNRTISPYRNVTFDELVEAYSESTHALIRGGADIILLETIFDTLNAKACAFAVSGVFELPVMISGTITSGRTLSGQTTEAFYNSLRHVKPISFG
LNCALGPDELRQYVEELSRISECAVSAHPNAGLPNA--FG--EYDLEAEEMAEHIHEWAQSGLNMVGGCCGTTPEHIRQMYEATKNIKPRQLPD--IPIA
CRLSGLEPLTIDAETLFINVGERTNVTGSARFKRLIKEELYDEALEVARQQVEAGAQIIDINMDEGMLDAKAAMIRFLNLCATISKVPIMVDSSKWEVLE
AGLKCVQGKPVVNSISLKEENFITQAKLLRRYGAAIIVMAFDEVGQADTRERKIEICTNAYRLLDEVGFPPEDIIFDPNIFAVATGIEEAVDFIEAVGDI
KRTLYAMVSGGVSNVSFSFAVREAIHAVFLYYCFKNGMDMGIVNAGQLAIYDDLPGEDVVLNRRDDSTERLAKYRDSGAEE----DRSAAERG-WPVEKR
LEHALVKGITEFIVEDTEESRQKASKPLEVIEGPLMAGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAYLEPYIDAEKAGQTNGKILLATVKGDVHDIGK
NIVGVVLQCNNYEIIDLGVMVSCDKILKVAKEENVDIIGLSGLITPSLDEMVHVAKEMERQGFDIPLLIGGATTSQNY---NQPVVYVSNASRAVGVCSA
LLS
>tr|Q1YT41|Q1YT41_9GAMM Methionine synthase OX=314287 OS=gamma proteobacterium HTCC2207. GN=GB2207_02542 PE=3 SV=1
------AAEQ-RILILDGAMGTMIQRHTLEEGQNNDLLSLTQPDIICDIHRAYLDAGADIIETNTFNSTTISQADDMISREINVVSAQLARKAADEPRFV
AGILGPTSRTLSPARNVTFDELVEAYIESTEALIEGGVDTIMVETIFDTLNAKAALFAVQVVFELPIMISGTITSGRTLSGQTPEAFWNSVRHSKPISVG
LNCALGPKELRPHLLDISTVADTLVSSHPNAGLPNE--FG--GYDLDADAMAETVAEFASAGLNIVGGCCGTTPDHIRVIANAVATIAPRVVPE--IEPA
CRLSGLEPFTIKSDSLFVNVGERCNVTGSAVFKRLILEENYDAALEVARQQVINGAQIIDINMDEGMLESLPAMVKFLNLIAGISRVPIMVDSSKWDVIE
AGLKCIQGKSVVNSISLKEAEFIERAKLCKKHGAAIVVMAFDEDGQADNLERRKQICQRSYDLLNEIGFPAEDIIFDPNVFAVATGIEEGLDFIEASGWI
KQNLHALISGGISNVSFSFPVREAIHSVFLYHAIREGLTMGIVNAGQLAVYDDLPEEDVVLFRNAEGTDALDKYRGDG-KQ----ASVEDSRD-ADVNRR
LEHSLVKGITAYITEDTEEARQQADRPLHVIEGALMDGMNIVGDLFGSGKMFLPQVVKSARVMKQAVAYLQPFIEDEKATSTNGKILMATVKGDVHDIGK
NIVGVVLQCNNYEVIDLGVMVSAEKILTTAREENVDIIGLSGLITPSLDEMVTLGKEMQRQGFTVPLMIGGATTSPNYE--NNQAIYVSDASRAVGVASK
LIS
>tr|H2FYG5|H2FYG5_OCESG B12-dependent methionine synthase OX=511062 OS=Oceanimonas sp. (strain GK1). GN= PE=3 SV=1
---LEQALAE-RILIIDGGMGTMIQSYRLDEGENNDLLVLTQPEIIAQIHSDYFAAGADIVETNTFNATTIAMADHMLAAEINLEAAKLARRVADEPRFV
AGVLGPTNRTISPYRNISFDQLVAAYTEATEALIDGGVDLLMIETIFDTLNAKAAVFAIEGVFRLPVMISGTITSGRTLTGQTTEAFYHSLRHAQPISFG
LNCALGPDELRQYVAELSRISETYVSAHPNAGLPNA--FG--EYDLDAAEMAAHIREWAESGLNLVGGCCGSTPEHIRAIAEAVKGIAPRPLPE--LPVA
CRLSGLEPVLITPESMFVNVGERTNVTGSAKFKRLIKEELYDEALEVALQQVENGAQIIDINMDEGMLDAEACMARFLNLIAGISRVPIMIDSSKWEVIE
AGLKCIQGKGIVNSISLKEAKFIEQARLVRRYGAAVIVMAFDEVGQADTRERKFEICQRAYRVLDKVGFPPEDIIFDPNIFAVATGIDEAVDFIEAVKDI
KDNLHAMISGGVSNVSFSFPVREAIHAVFLYHAIKNGMDMGIVNAGQLAIYEDIEPEAVVLNLNDNATEALERYRNSGPAN----DARDLERS-WPVNKR
LEHALVKGLTDFIEEDTEEARQQAARPLDVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKRAVAYLNPYIEATKVGQSNGKIVMATVKGDVHDIGK
NIVGVVLQCNNFEVVDLGVMVPCETILKTARETNADMIGLSGLITPSLDEMVHVAKEMQRQGFKIPLLIGGATTSQNY---DEPVVYVSNASRAVGVVQS
LLS
>tr|D0Z1R6|D0Z1R6_LISDA 5-methyltetrahydrofolate--homocysteine methyltransferase OX=675817 OS=Photobacterium damselae subsp. damselae CIP 102761. GN=VDA_003480 PE=3 SV=1
---LQQRLAE-QILIIDGGMGTMIQGYKLAEGENNDLLVLTQPQIITDIHQQYLAAGADILETNTFNATTIAMADEMFSAEINLVAAQLARQAADEPRFV
AGVLGPTNRTISPFRNITFEQLVIAYSESTRALIKGGVDLILIETIFDTLNAKACAFAVESVFQLPIMISGTITSGRTLSGQTTEAFYNALRHVKPISFG
LNCALGPDELRQYVAELSRLAECSVSAHPNAGLPNA--FG--EYDLEPEEMAEHIAEWAQSGLNLVGGCCGTTPEHIRQMAAVTQNIKPRTPPS--IPVA
CRLSGLEPLNIEKNSLFINVGERTNVTGSARFKRLIKEELYDEALEVARQQVEAGAQIIDINMDEGMLDAKAAMVRFLNLCATIAKVPIMVDSSKWEVIE
AGLQCVQGKPIVNSISLKEAKFIEQAKLIQRYGAAVIVMAFDEEGQADTRERKVEICTQAYRILDEVGFAPEDIIFDPNIFAVATGIEEAVDFIEAVGEI
KATLHAMISGGVSNVSFSFPVREAIHAVFLYYCFQKGMDMGIVNAGQLAIYDDLPQEDVVLNLREDSTERLEKYRGTGVEE----DRSAQERS-WPVEKR
LEHALVKGITEFIVEDTEQARALAAKPLEVIEGPLMAGMNVVGDLFGEGRMFLPQVVKSARVMKQAVAYLEPFINAEKAGSSNGKILLATVKGDVHDIGK
NIVGVVLQCNNYEIIDLGVMVSCEQILKVAKEEQVDIVGLSGLITPSLDEMVHVAKEMERQGFELPLLIGGATTSQNY---HAPVVYVSNASRAVGVCSA
LLS
>tr|B8KGM0|B8KGM0_9GAMM Methionine synthase OX=566466 OS=gamma proteobacterium NOR5-3. GN= PE=3 SV=1
---LADALRK-RILVIDGAMGTMIQAEGLQEGENNDLLSITRPDVIKGIHLAYLEAGADIIETNTFNATAVALEDGLIARELNETSAHIARSAAQAPRFV
AGVLGPTPRTISPARNVDFARLSDDYSEAVRGLLDGGVDLLMIETIFDTLNAKAAIFAIESVFRVPVMISVTFPSGRNLSGQSPTAFWYSVAHARPLVVG
SNCGRRFLEVRPFLEELSKATQGYFSAHLNAGLPNA--FG--EYDEAPEVMAAEFKDFAERGVNLVGGCCGTTPAHIRAIAHAVEGIAPRALPE--SSGA
CQLSGLEPFTFDAQSLFVNVGERCNVTGSARFKKLILSGDYEAALDVARTQVEDGAQIIDVNMDEGMLDAKEAMVTFLNLIASISRVPVMIDSSRWEVIE
AGLRCVQGKAVVNSISLKAEEFLEQARLCQRYGAAVVVMAFDEDGQADTVARRREICQRSWDLLERLDFNPEDIIFDPNIFAVATGIEIAVDFIEATRWI
KENLGAKVSGGVSNVSFSFPVREAIHSVFLYHAIRAGMDMGIVNAGQLAVYDELPGEDVVLNRRDDSTERLSKYHADG-PV----RVEDLARD-EPVTKR
LEYALVKGINNYIEEDAEEARQQAARPIEVIEGPLMDGMNVVGDLFGQGKMFLPQVVKSARVMKQAVAYLQPYIEEEKE-STNGRILMATVKGDVHDIGK
NIVGVVLQCNNYEVIDLGVMVHCEEILRVAKEQNVDIIGLSGLITPSLDEMMHVASEMQRTGL-VPLMIGGATTSPNYQ--NDLVVYVPDASRSVSVASQ
LLG
>tr|B2Q553|B2Q553_PROST Putative uncharacterized protein OX=471874 OS=Providencia stuartii ATCC 25827. GN=PROSTU_04024 PE=3 SV=1
---LEQELQK-RILVLDGAMGTMIQRHKLTEGENNDLLVLTQPEIIRDIHDQYFAAGADIVETNTFNSTTIAMADKMLSAEINEAAARIARECADEPRYV
AGVLGPTNRTISPFRNINFDQLVEAYRESTHALIKGGVDLIMIETIFDTLNAKAAIFAVETEFTLPVMISGTITSGRTLSGQTTEAFYNSLRHARPLSFG
LNCALGPNELRQYVSELSRIAECYVSAHPNAGLPNA--FG--EYDLDAQNMAEQIREWAQAGLNIVGGCCGTTPLHIKKIVEAVKGIAPRALPK--LPVE
CRLSGLEPLNIGKDSLFVNVGERTNVTGSAKFKRLIKEGNYQEALDIARQQVENGAQIIDINMDEGMLDSEAAMVRFLNLIAGIARVPIMIDSSKWDVIE
KGLKCIQGKGIVNSISMKESAFIEHAKLVRKYGAAVIVMAFDEVGQADTRERKIEICRRAYHVLDTVGFPPEDIIFDPNIFAVATGIEEAVDFIEVCQDI
KQQLHAMISGGVSNVSFSFPVREAIHAVFLYYAIRNGMDMGIVNAGQLAIYDDLPKEDVILNRREDSTERLEKYRAS--GS----EEQQAERS-WAVEKR
LEYALVKGITEFIIPDTEEARQLAASPIEVIEGPLMNGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAYLEPYIQALKSGSSAGKILLATVKGDVHDIGK
NIVGVVLQCNNYEIVDLGVMVPCETILKTAREQNVDVIGLSGLITPSLDEMVHVAKEMERQGFTIPLMIGGATTSPNY---SHSVTYVQNASRTVGVVSA
LLS
>tr|Q47K26|Q47K26_DECAR Methionine synthase (B12-dependent) OX=159087 OS=Dechloromonas aromatica (strain RCB). GN= PE=3 SV=1
---LSSLLQQ-RLLVLDGAMGTMIQRHGLQEGENNDLLVLTRPDIIGGIHREYLEAGADILETCTFNSTAVSQADNLLVYELNFEGAKLARQLCDEPRFV
AGVLGPTSRTISPYRNVTFDELVANYVEAITGLVEGGADILLVETVFDTLNAKAALFAIEKFFRWPVMISGTITSGRTLSGQTAEAFWNSLRHVQPVSFG
LNCALGAKELRQYVEELSRVCDCYVSAHPNAGLPNA--FG--GYDETADMLADEIESWAKAGVNIVGGCCGTSPEHIAAIAQRVATVSPRQRPA--IEPA
LRLSGLEAFNVTPGSLYVNVGERTNVTGSKAFARMILEGRFDDALAVARQQVENGAQIIDINMDEAMLDSLAAMDKFLKLIASISRVPIMIDSSKWEVIE
AGLKCIQGKGIVNSISMKEAKFIEQAKLARRYGAAVIVMAFDEKGQADTFARKTEISKRAYDLL--IGFPAEDIIFDPNIFAIATGIPEAVDFIESVRWI
KQNLHAHISGGVSNVSFSFPVREAIHTVFLYHAIKNGMTMGIVNAGMLGIYDDLEPEDVVLNRNPNAGEALQTVKGKA-D-----TGPDLSRE-QSVEKR
LEHALIKGITDFVVADTEEVRAQLEAPLAVIEGPLMAGMNHVGDLFGAGKMFLPQVVKSARVMKQAVAHLLPYIEAEKTGGSKGKILMATVKGDVHDIGK
NIVGVVLGCNGYDVIDLGVMVSCDNILKAALEHRVDIIGLSGLITPSLEEMAHVASEMQRQGMKQPLLIGGATTSPNT---EGAVVYVPDASRAVGVATK
LLS
>tr|A0LDY2|A0LDY2_MAGSM Methionine synthase (B12-dependent) OX=156889 OS=Magnetococcus sp. (strain MC-1). GN= PE=3 SV=1
---FRTLLQQ-RILILDGAMGTMIQRLGLEEGSANDLLVLTKPQVIRNIHTAYLEAGADIVETNTFNGNAPSLGDGLLVYEVNLEGARVARQACDAICFV
AGVLGPTNRTISPFRNIDFDALVADYANGTRGLLDGGADILLVETVFDTLNCKAALFAVRQVLDLPLMISFTITSGRTLTGQTVEAFWNSVSHARPDTIG
MNCALGADQLRPHLETLAEIAATRISVHPNAGLPNA--FG--EYDETPAMMADKVVAFAQGGINIVGGCCGTSPDHIRAIAQRVAGLAPRQIPL--KP-A
CHLSGLEPLTIDADSLFVNVGERTNVAGSARFARLIREGQYETALAVAREQVESGAQIVDVNMDDAMLDAQSAMVTFLNLMAAISRVPVMIDSSEWRVLE
AGLKCVQGKCIINSLSLKEEPFLKQAHLARRYGAAVIVMAFDEQGQADSYQRRIDICQRAYDLLHTVGMEPNDIIFDPNIFAVATGIEEAVEFIQATRWI
KQNLGARISGGVSNVSFSFPVREAMHAVFLYHAIAAGMDMGIVNAGQLAVYEEIPVEDVILNRRSDATDRLDHYRSG-VTE----DKADAARS-EPVQAR
LRHAMIKGITEFIDADVEEARSLAAHPLEVVEGPLMAGMNAVGDLFGEGKMFLPQVVKSARVMKQAVAYLVPHIEEANQRSGAGKILLATVKGDVHDIGK
NIVKVVLQCNNFEVEDLGVMVAVETILDRAQESGAQIIGLSGLITPSLQQMTHVAKEMQRRGMQIPLLIGGATTSPVT---EGCVVQVKDASRSVGVAAA
LLS
>tr|K6H329|K6H329_9GAMM Methionine synthase OX=1208365 OS=SAR86 cluster bacterium SAR86E. GN= PE=4 SV=1
---LSQILDK-QILLLDGAMGTMIQAHDLQEGKNNDLLTLTQPGIISEIHRKYIDAGANIIETNTFNSNAPSMADEMLVHELNFEAAKLARKAADDDIFV
AGVLGPTNRTLSPQRNINFDQLVSTFSEATEALIDGGADLLLVETVFDTLNAKAAIFAIDCVADIPIMISGTITSGRTLSGQTTEAFWHSVRHANPISIG
LNCALGAAELRPFLQKLSQISNCYVSAHPNAGMPNQ--FG--EYDQTAAEMAEIIKEFGQEGLNIVGGCCGTTPSHIELIRDVVSDLPPRKVVD--AAEA
MLLSGLEPLEISSESLFINIGERTNVTGSAIFRKLIEAGDYEAAIQVARQQVENGAQIIDINMDEGMLDSEFAMVKFLNLIAGISRVPIMVDSSKWSIIE
AGLKCIQGKAIVNSISMKEEQFIEQARLVKRHGAAVVVMAFDEEGQAETLQRKVEICKRAYDILNTVEMDPRDIIFDPNVFAVATGIEEGLSFIEACAEI
KKVCGVSISGGLSNVSFSFVLREAMHSVFLYHAIKNGLTMAIVNAGQLAIYDDIPLEDVILNRSPNATEQLPKY-ADSSSV----INQDQDRN-LQVNDR
LNHSLVTGVDTFVIEDVEEARLLAEKPLDVIEGPLMDGMNRVGDLFGAGKMFLPQVIKSARVMKKAVAYLVPFIEEEKGEQSNGKMVLATVKGDVHDIGK
NIVGVVLQCNNFEVIDLGVMVPTDKILDVAEKENCDLIGLSGLITPSLDEMVGVAKEMDRRGLSIPLLIGGATTSPNY---NGTVVYVKDASRAVSVAQR
LIG
>tr|K2IYV8|K2IYV8_9GAMM B12-dependent methionine synthase OX=745411 OS=Gallaecimonas xiamenensis 3-C-1. GN= PE=3 SV=1
---LLAALKD-RILIIDGGMGTMIQNRQLEEGDNNDLLVLTQPKVIKDIHRQYLLAGADIIETNSFNATPIAMADGMLSKEINLEAARLARQAADEARFV
AGVLGPTNRTISPFRNVSFDQLVAAYTESTEALIDGGADIILVETIFDTLNAKAALFAVDALFKLPVMISGTITSGRTLTGQTTEAFYNSLRHVRPLSMG
LNCALGPKELAPYIEELSRIAECYVSVHPNAGLPNE--FG--GYDETPEQMVEFIGQWALDGLNLVGGCCGTTPAHIKAMAEAVKGLKPRALPD--IPVA
TRLAGLEPCNIFADSLFVNVGERTNVTGSARFLKLIKSGDYETALEVARQQVEAGAQIIDINMDEGMLDAEAAMVRFLNLIASISRVPIMIDSSKWHAIE
AGLKCIQGKGIVNSISMKEENFKAQARLIRRYGAAMVVMAFDEDGQADTYQRKVEICTRAYRILDEVDFPPEDIIFDPNIFAVATGIDEGVAFIEACRTI
RDTLHARISGGVSNVSFSFPVREAIHAVFLYHAIKAGLSMGIVNAGQLAIYDDIDDEDVVMNRRDDSTERLDDYRGDGEKE----AQTQA-RE-LPVNKR
LEYALVKGITDFIDEDTELARAAATRPLDVIEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKKAVAYLTPYIEAEKEGKSNGRVVMATVKGDVHDIGK
NIVGVVLQCNGFEVIDLGVMVSVEKIIEAAKTHNADVIGMSGLITPSLDEMIHNVKAFKKAGISLPVIIGGATTSPHY---EHGALYVADASRTVPVVSK
LIG
>tr|H5SHG0|H5SHG0_9GAMM 5-methyltetrahydrofolate--homocysteine methyltransferase OX=86473 OS=uncultured gamma proteobacterium. GN=HGMM_F29A09C15 PE=3 SV=1
---IRQILAE-RILILDGAMGTLIQAHGLSEGKNNDLLSLTQPEIVSEIHRRYLEAGADLIETNTFNANRISLADGMLARELNFAAARLARQAADAPRFV
AGVLGPTNRTISPFRNVSFQDLVVAYTEAVAGLIEGGVDLILIETVFDTLNAKAAVFAVKQYLERPLLISGTITSGRTLSGQTPEAFWNSLRHAEPLAFG
FNCALGPKELRQYVEEISAYVDTFVSAHPNAGLPNA--FG--GYDETPETMAEEIGAWAKEGLNIVGGCCGTTPDHIRAIAEAVAGAPPRRVPK--PKVM
TRLAGLEPLNIGPDSLFVNIGERTNVTGSAHFRRLIQEGRYDAALEIARQQVANGAQMIDVNLDEGMLDSKAAMVRFLNLVAAIARVPVMIDSSKWEVIE
AGLQCLQGKGVINSISLKEETFLAHARLARLYGAAVVVMAFDEQGQADTKERKVEICTRAYRLLEKLDFPPEDIIFDPNVFAVATGIPEGLDFLEAVAEI
KNTLYALTSGGISNVSFAFAVREAIHAVFLYHAIRAGLDMGIVNAGQLGIYEEVPWEDVLLCRREDADERLASYR-GA-EA----KVQELERS-WPVEKR
LEHALVQGIADYIEEDTEEARKLLGSPLAVIEGPLMAGMNVVGDLFGAGKMFLPQVVKSARVMKKAVAHLEPYLKAERQEKSAGKVLLATVKGDVHDIGK
NIVGVVLQCNGFEVVDLGVMVPADKILHAAREQQVDIVGLSGLITPSLDEMVHVAKEMARQGLDIPLLIGGATTSPHY---AAPVVYVPDASRAVGVVGS
LLS
>tr|B8KQY4|B8KQY4_9GAMM Methionine synthase OX=565045 OS=gamma proteobacterium NOR51-B. GN= PE=3 SV=1
----MKSLEE-RIVILDGATGTALQKYALDEGSNNDLLNLTQPDIVSEVHRSYLDAGADIIETNTFNGTRIAQSDGLLVDEINLAGAQLARSAADVPRYV
AGVLGPTPRTISPARNITFEQLVDDYQSAAETLIDGGVDLLMVETIFDTLNAKAAIFAIEAAMVLPLMLSVTFPSGRLLSGQTGEAFWHSIAHAKPLVVG
SNCGRRFTEVQPFLESLANVAPCYFSAHLNAGLPNA--FG--EYDETPEDMHSDFKGFAERGLNLAGGCCGTTPEHIRAIADAVEGVAPRSIPE--PLPD
TRLSGLEPFEFAGKN-FVNVGERCNVTGSAKFKRLILDNDFDTALDVARTQVEDGAQIIDVNMDEGMLDSKAAMIQFLRMAAAIAKVPFMIDSSKWEVIE
AGLKCVQGKAVVNSISLKSAEFLEQARLCQRYGAAVVVMAFDEEGQADTLERRQHICRRSYDLLERLDFNPCDIIFDPNIFAVGTGIEAALDFIEATRFI
KQDLGARVSGGVSNVSFSFAVREAIHSVFLYHSIKAGLDMGIVNAGQLAVYDDLPDLDLVLNRRDDATERLESYRSAG-GR----RNEDLTRE-QEVEKR
LEYALLKGITNWIEEDTEEARQRANKPIEVIEGPLMDGMNTVGDLFGEGKMFLPQVVKSARVMKQAVAYLQPYIEEEKG-GNNGKILLATVKGDVHDIGK
NIVGIVLQCNNFEIIDLGVMVHCDEILRVAEEENVDIIGLSGLITPSLEEMSHVAREMQRRNL-TPLMIGGATTSPEYQ--NNTVVYVPDASRSVAVASK
LVG
>tr|C9P2V8|C9P2V8_VIBME 5-methyltetrahydrofolate--homocysteine methyltransferase OX=675813 OS=Vibrio metschnikovii CIP 69.14. GN=VIB_002140 PE=3 SV=1
-------------------MGTMIQSYQLQEGNNNDLLVLSQPSLIKEIHHAYLAAGADILETNTFNSTTIAMADDMLSAEINYVAAQLARQVADEPRYV
AGVLGPTNRTISPYRNVSFDQLVDAYSESTRALIEGGCDLIMIETVFDTLNAKACAFAVDCIFALPVMISGTITSGRTLSGQTTEAFYHSLRHVRPLSFG
LNCALGPDELRPYVAELSRISESYVSAHPNAGLPNA--FG--DYDLGPEEMAEHIAEWAQAGLNLVGGCCGTTPEHIAAMAKAVEGVVPRRLPE--LNVA
CRLSGLEPLTIAKGTLFVNVGERTNVTGSARFKRLIREELYDEALDVAREQVANGAQIIDINMDEGMLDAKACMVRFLQLCASISKVPIMVDSSKWEVIE
AGLKCIQGKGIVNSISLKEAKFIEQAKLVRRYGAAVIVMAFDEVGQADTRERKVAICSNAYRILDEVGFPPEDIIFDPNIFAIATGIDEAVDFIEAIADI
KRDLYAMISGGVSNVSFSFYVREAIHAVFLYHCFKHGMDMGIVNAGQLEIYDNVPVEDVVLNRRPDATERLEQYRDNAKVD----DPALLERS-WPVAKR
LEHALVKGITEFIIEDTEDARQQSSRPLDVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAYLEPYINALKASSANGKILLATVKGDVHDIGK
NIVGVVLQCNNYEIIDLGVMVPCEQILKVAKEQQVDIIGLSGLITPSLDEMVHVAKEMERQGFNLPLLIGGATTSQNY---RHPVVYVNNASRAVGVCSA
LLS
>tr|C6UN88|C6UN88_HODCD Putative B12-dependent methionine synthase OX=573234 OS=Hodgkinia cicadicola (strain Dsem). GN= PE=3 SV=1
---LTAISSK-RALVLDGAMGTQIQKFKLKPVENNDALNMTQPKVVEGVHAAYAAAGSDVLSTNTFCSCSVSQADGTSCSDLNARGCLIARRACLKRVFV
AGVLGPTNKSIPAHRDVTFDDLVLSYRQQADALLASGADALLVETVFDTLNAKAGLKACIDASRRALVASATISSGRTLSGQTIEAFWVSVKHANLAGVG
LNCALGPAQLSRHAAALALAAEAPIWVYPNAGLPNE--MG--KYTQGAKAFAHALKRCF--GASAVGGCCGSTPEHISELKALKPKSASRKL-R--QPLA
C---GTDLV-LAPTT-LCKVSERANVAGSSRFKTLIARKNYSEALEVVRAQACGGAHAIDVNFDDAMLDPKAEMCRFLSLLAALAKMPVVIDSSSWDVLV
AGMKLTQGRSIVNSISLKDEPFVSKAQTIKTLGCVPITIAFDELGQATTCERRLEICRRAFKLLARAGYAPQDVIFDLNTFAVATGIPEAAMLLKAIKLV
RCVFSVTISAGVSNLSFAFRIRRALHSAFLESARGAGLNMAIVNTQEASSGEAATAKALILNLRS-VTEEVASA-GV--PR----RQAPTSRS-WSARAR
VAHAVVSGTDKHVADDSVELAKSVG-ALAVVEGALMDGMSVVGKLFEKGKMFLPQVVKSARVMKKAVQALAPMLAPRE-AAKPHTVVLATVKGDVHDIGK
NIVATVLACNSFRIVDLGIMAASDAIVSAAIAEDAVAIGLSGLISPSLDEMARVARKLQARGVTTPLLVGGATTSPEYQ--GGVVIHVSDASKAVDVLTK
LSS
>tr|K5D432|K5D432_RHILU B12-dependent methionine synthase OX=1229491 OS=Rhizobium lupini HPC(L). GN= PE=4 SV=1
----------------------------------------------------------------------------------------------------
---------------------------------------------------------------RLPVMISGTITSGRTLSGQTPSAFWNSVRHANPYXIG
LNCALGADAMRPHLQELSDVADTFVCAYPNAGLPNE--FG--QYDETPEMMARQVQGFARDGVNIVGGCCGSTPEHIRAIAEAVKDYKPRPIPE--HKPF
MSLSGLEPFVLTKDIPFVNVGERTNVTGSAKFRKLITAGDYTAALAVARDQVENGAQIIDINMDEGLIDSEKAMVEFLNLIAAIARVPVMIDSSKFEIIE
AGLKCVQGKSIVNSISLKEEKFLQQARLVHNYGAAVVVMAFDEVGQADTYQRKVEICARAYKLLEKAGLAPEDIIFDPNVFAVATGIEEGVDFIEATKTI
RETMLTHISGGVSNLSFSFPVREAMHAVFLYHAIQVGMDMGIVNAGQLAVYDNIDPEDVVLNRRDDATERLERFRGT--GA----KDTDLSRE-LPVEKR
LEHALVNGITDYIEADTEEARQKAERPLHVIEGPLMAGMNVVGDLFGSGKMFLPQVVKSARVMKQAVAVLLPYMEEEKLNKAAGKVLMATVKGDVHDIGK
NIVGVVLACNNYEIIDLGVMVPTTKILETAIAEKVDVIGLSGLITPSLDEMVHVAAEMERQGFDIPLLIGGATTSPRY---EGQAIYVTDASRAVGVVSA
LLS
>tr|E6PI36|E6PI36_9ZZZZ Methionine synthase (5-methyltetrahydrofolate--homocysteine methyltransferase) (Methionine synthase, vitamin-B12 dependent) (MS) OX=410659 OS=mine drainage metagenome. GN= PE=4 SV=1
MTSYLDALRE-RVLLFDGAMGTQLMALELTAG-CNEALVLSRPDLIRSIHERYFEAGADVVETDSFTASRLKLDEGIHTYAVNHDAARLARKAADLPRFV
AGSMGPTGMLVPSLSKITFEELAALYGEQARALVEGGVDLLLLETMQDLLELKAAIVGIREGRRVPIQAQPTLIEGRMLLGTDISSVCAVLDALPIDVIG
LNCSTGPAQMRDSVRYLGETSRCYVSVIPNAGLPLMGPKGETIYPETPSELTSELMEFVSFGVRAIGGCCGTTPEHIASLRAALDASPASRAAAP-PRPE
FVASAMTAVSLEQEPRPLIVGERINSQGSRRVKRLLLEDDYEVIGQLARDQIEGGAHVLDVCTALTETDEPEQMRAVVRRLAQSVEAPLMIDSTEAAVVR
SALENYPGRAIVNSVHLERTKIDAILPMAIEHGAAVVALTIDESGMAKTAQRKLDVARRIYDIVGEYGLAPGALIFDDLTFTLATGDAEARESIDGIRAI
KAALGVLTSLGVSNVSFGLKARAALNSVFLHHCVEAGLDLALVHPKEITPAEAREACDLVFNRRPALARFIERYENAVVR-----SDEDTANDGLPAEAR
IHRAILHRKKDGIETMLDEVLLRR-TPVEVLNEVLLPAMKEVGDRFGAGELILPFVLQSAEVMKRAVAHVEQFLERRE-GSTKGTVVLATVFGDVHDIGK
NLVNTILSNNGYTVYDLGKQVPMNVILEKATEVNADAIGLSALLVSTSKQMPICVQEQDARALAFPVIVGGAAINRDFGRRIPGVFYAKDAFEGLDIMD-
---
>tr|E6PZQ3|E6PZQ3_9ZZZZ Methionine synthase (5-methyltetrahydrofolate--homocysteine methyltransferase) (Methionine synthase,vitamin-B12 dependent) (MS) OX=410659 OS=mine drainage metagenome. GN= PE=4 SV=1
-----------------------------------------------------------MIETDSFGSTDIVLAEELRTRELNLAAARLAREVADQPRFV
AGSMGPTTKL-PSLGHIGYDAMAASYRQQAEALIEGGVDILLVETSQDLLQAKIASA-IAAGRRVALQVQVTLETGTMLLGSEIGAALAVLEAMQPDVIG
LNCATGPEEMNDAVRFLCQNSTLPICIQPNAGLP--NEGGHAVYKLTPAELAAHHRRFVEYGVAVVGGCCGTTPEH---LRAVA-----------EPQ--
VVASAFTAVPLEVDGQPVVIAEEMNTTTR--FRNLVRGGDYEGILTMAKRLVGEGSQMLDLCCAIVG-DEQAYMNGVLEKIATRVPAPILVDSTEAEVIE
EALKRIPGKPVINSINLEEKRTSRVLPMARRYGAAVIALTIDEDGMALTADKKVAIAHRIHDMAHRYGLRAQDIIFDPLTLPISTGQEDAIETLEAVRRI
KLDLGVKTVLGVSNISFGLNARRVLNSVFLKEAVDRGLDTAIVNYSRIYPEKEVELARLIFQ-RVPLQAYMGYFA-----------VP-----DLSVEDR
LKQLIIR-QKQTLEEAIEAALVSY-SPLALINDVLLDGMKTVGELFGARKMQLPSVLDSAAVMKAAVAYLEPKMEKSD-GGGKGTMVLATVKGDVHDIGK
NLVDIILTNNGYRVINLGIKQPSDVIVAAARAQATDSIGLSGLLVKSTLEMKYVLQDLERLGLEIPVICGGAALTRKY----GPVYYAEDAFAGLNIMD-
---
>tr|C1EAX2|C1EAX2_MICSR Predicted protein OX=296587 OS=Micromonas sp. (strain RCC299 / NOUM17) (Picoplanktonic green alga). GN=MICPUN_105867 PE=3 SV=1
---INKIMKE-RIMVIDGAMGTAVQKYKLSEKGNNDVLVITRPDVIEEIHTAYLAAGADIIETNTFNSTMISQADELEVYLLNKTAAQLAKKCCVEPRFA
AGAVGPTNKTLSPFRGCTYDEIVEAYYEQVEALIDGGVDVLLVETIFDTLNAKAAMFAIDMYQKIPVFVSGTIVSGRTLSGQTNEAFWNSMSHSKPIAIG
LNCALGAKDMVPYIENLSRVADCWVFCYPNAGLPNA-MGG---YDQKGAEMAEDCRVFPEKGINAIGGCCGTTDEHIKCLADMVATYKPRERHDV--PDI
MRLSGLEPFNYAPRKTFINLGERCNVAGSTIFKKAIVDGNYEKALAIALKQVENGAHVIDVNMDDGLIDGESAMTKFVNLMVSVAKVPFMIDSSKFHVVE
AGLKCSQGKCIMNSISLKEEEFLNQAKIVKRHGAAVVVMAFDEEGQAATEAEKVRICCRAYKLLEKVGFNPQDIIFDPNILTIGTGMEEGVDFINATREI
KRLCGCKISGGVSNLAFSFPVRRAFHSAFLYHACKAGMDMGIVNAAQVEVYEKIDVEDVLLNRCTNATERMLEFAKSKPTAGGAGAAKKDDAKAWRVGKR
LEHALVKGIDEFCIADTEECRTNGDTPLEIIEGPLMDGMNVVGDLFGAGKMFLPQVIKSARVMKKSVGHLIPFMEEEKREASAGVFLIATVKGDVHDIGK
NIVAVVLGCNNFKVIDIGVMCPKDKIIDALKEHNADICGLSGLITPSLDEMVDMAKAMEAEGMKIPLLIGGATTSKMTAVKLAPVVHVLDASRAVPVAQT
LM-
>tr|K3WL46|K3WL46_PYTUL Uncharacterized protein OX=65071 OS=Pythium ultimum. GN= PE=3 SV=1
---LSALMKQ-RTLIFDGGMGTMIQQYKFSEKGNNDLLSLTQPEVIRTIHKQYMEGEAQMIGTNTFSGTTIAQADKMLVYELNYESARIAREAADEPRFV
AGSIGPTNRTLSPFRNVTFDELVEAYYTQIEGLVDGGSDILLVETIFDTLNAKAAVYAVDVYKKLPLFISGTIVSGRTLSGQTTEAFYVSLRHSKPFCIG
LNCALGANQMKPFLQRLSNVAECFVSVYANAGLPNA-MGG---YDDGPALMAEYCEEFCKDQINMMGGCCGTTPAHIKAIADVCGKYAPRPLPPP--KPF
MWLSGLEDLVVTK-FSFLNVGERCNISGSIRFKKLIMKGDYGTAMDIARQQVEDGAMVIDVNVDDGMLDGVAAMERFLKIAVTVSKVPFMVDSSKFHIVE
AGLKCVQGKCIVNSISLKKELFCEHARIVKRHGAAVVVMAFDEDGQAATEAEKVRICKRSYDILNEVGFPPEDIIFDPNILTVATGMEEGVDFINACKVI
KEQNYCKISGGVSNLSFGFVIREAIHSVFLYHAVKAGMDMGIVNAGMLEVYDDIPCEDVVLNRHPGATEALLDRSLIEKEKGVVA---TTNQQEWRIAER
LTHSLVKGISEFIDQDVEEMRKVSARPLDVIEGPLMDGMNVVGNLFGAGKMFLPQVIKSARVMKKAVAYLLPFMEEEKNEDSAGKVLMATVKGDVHDIGK
NIVGVVLGCNNYKIIDMGVMVPCEDILRVAREENVDIIGLSGLITPSLDEMVYVAREMSKAGMKIPLMVGGATTSKMAAVKIAPVIHVLDASRSVVVVGN
LL-
>tr|C5K5V1|C5K5V1_PERM5 Methionine synthase, putative OX=423536 OS=Perkinsus marinus (strain ATCC 50983 / TXsc). GN=Pmar_PMAR026737 PE=3 SV=1
---LRQLFSE-RIVLLDGGMGTRIQADRLQEKGDNDLLCLTRPDLVVKIHKEYLHAGADLIETNTFNGTTISQAEQCLVRDLNFQAAMLAKQACRERRLV
AGAIGPTSRTLSPYRNVTWNELVKAYYEQVDALVAGGSDVLLVETIFDTLNAKAALFAIDCYSRLPTIISATIVSGRTLSGQTIDAFLVSVMHARPLCVG
INCALGAAQMRPFFETLAKLAPVYVHVYPNAGLPNA-MGG---YDETPESFGESLVLYAQDHINMVGGCCGTFPAHIQAVHERLKSFPPRPLHVR--RPV
MRLSGLEPLYLTPELGFVNVGERCNLMGSLRFKKMVEQSRWDDALEVAKEQVENGAQVLDFNFDADLIDGQLAMGRFMRSCVTIARVPFMIDSSKFKVIE
EGLQAVQGRCIVNSLSLKEEDFIYHARLVRKYGAALVCMAFDEEGQAATFDDKIRICERTYKILTKCGYEGHDIIFDCNILTIATGMEEGKDFIDAVEIV
RQKCGCYTSGGLSNLSFSFELREAMHSVFLYHAIPKGLSMAIVNAGALPIYTDIPLEDVVMNVSPEATEKLLEFAELKEKKGGA-SGVVKAVEEWRVEKR
LEHSLVKGIDKFIVDDVQECD----RPLEVIEGPLMAGMSVVGDLFGSGKMFLPQVIKSARVMKKAVAHLVPIMETENRDR-AGTVLLATVKGDVHDIGK
NIVGVVLGCNNFRVIDLGVMVPCDQILKRAREEKADVIGLSGLITPSLDEMVFVAQQMRKESMDVPLLIGGATTSRKTAVKIWPVVHVLDASRSVVVVNS
LI-
>tr|E1ZPJ8|E1ZPJ8_CHLVA Putative uncharacterized protein OX=554065 OS=Chlorella variabilis (Green alga). GN=CHLNCDRAFT_36916 PE=3 SV=1
---LEAMMQE-RIIFIDGAMGTMIQRYKLQEKGNNDLLVLTRPDVIEEIHTAYLTGGADIIETNTFNGTTISQADQLEVALINRTAAQLAKKATAARKFV
AGAIGPTNKTLSPLRGVTYDEIEQAYYEQARALYEGGVDMYLVETIFDTGNAKAAIYALERFVRIPVFISGTIVSGRTLSGQTNEAFWNSVSHAKPLAIG
LNCALGASDMKQYIANLSACADCYVFCYPNAGLPNA-MGG---YDQRGPDMAEDIRPFCEEGVNAIGGCCGTTPEHIAAIREMASAYPPRQLHDV--PQL
LRLSGLEPLNYQPRETFLMIGERCNVAGSIIYKKAIVDGDYDKAVSIALSQVNAGAHVLDINMDDGLIDGVPAMTRFVNLLVSASRVPFMVDSSKFFIIE
AGLKCCQGKCIVNSISLKEDKFREQARIVKRHGAAVVVMAFDEEGQAADCANKVRICQRAYRILEEVGFNPQDIIFDPNILTVGTGMAEAVDFIRGTREI
KRLCGAKISGGVSNIAFSFPVRRAFHSAFLHHACKAGMDMGIVNATQVQVYEKIDVEDVLLNRCENATERMLEYAKCKPTDVAQ--NGGPKQDEWRVEKR
LEYALIKGIDKFVVADTEEARVSGRRPLNVIEGPLMDGMNVVGDLFGAGKMFLPQVIKSARVMKRAVGHLIPYIEEEKADD-AGVIIMATVKGDVHDIGK
NIVGVVLGCNNFKVIDMGVMCPWEKILDAAVEHNADIIGLSGLITPSLDEMVTVAKRMEERGLRLPLLIGGATTSKMTAVKIEPVVYVLDASRSVPVAQS
LL-
>tr|A9V1Z5|A9V1Z5_MONBE Predicted protein OX=81824 OS=Monosiga brevicollis (Choanoflagellate). GN=37476 PE=3 SV=1
---LDAILQQ-RIMFLDGAMGTLIQTLKLEEQGNNDVLVLTMPDDIVELHKRYLRAGADIVETNTFNANVISQADAMLVERLNIEAARVARRACDEKKYV
AGAVGPTNRTLSPLRNITFPELVKAYSQQIRALIEGGVDILLVETIFDTANAKAALFAIDALPRLPLLISGTITSGRTLSGQTPDAFTVSVSHANPLALG
LNCALGAEDMRPHLEEIAKATDAYIICYPNAGLPNA-MGG---YDETPEITGSHVEAFARDGLNIVGGCCGTMPEHIASIVQKCSKFSPRPRPPK--PNE
MLLCGLETFLIGENTNFVNIGERCNVAGSARFCRLIKENKYDDALAVAKSQVENGAQVIDINMDDGMLDGIKAMTTFCNLIASISRVPLCIDSSNFDVVK
AGLECVQGKCIVNSISLKVDDFKNKASIIKRYGAAVVVMAFDEDGQAADLDGKIRICQRSYRILEEVGFNPNDIIFDPNILTIGTGIAEGVNFIKCIRPI
RESCGAHISGGVSNLSFAFAVRESMHSVFLYHAIKEGMDFGIVNAGVMPIYTEIDCEDLILNRDPDATEKMLAFAQSM---TAEV-KKDEKVDEWRVEKR
LEHSLVKGIDKFVVEDTEEARLNTLKPLNVIEGPLMAGMSIVGDLFGAGKMFLPQVIKSARVMKRAVAHLIPFMEAERDDVSNGTMVIATVKGDVHDIGK
NIVAVVLGCNNYKVVDLGVMVPANKILDACREHKADVLGLSGLITPSLDEMIFVAKEMQRTGLDIPLLIGGATTSKMTAVKIAPVIHVLDASRSVVTVSS
VL-
>tr|J9IJQ2|J9IJQ2_9SPIT Cobalamin-dependent methionine synthase OX=1172189 OS=Oxytricha trifallax. GN= PE=3 SV=1
---LENTFKQ-RIVILDGGMGTQLQTYKLQEKNNSDILNLTQPEIVTEVHKAYLEAGADIIETNTFNGTTISQSDKLLTFEMNYQAAKLARKASDQWRLV
AGAIGPTNRTASPFRNVTYMELKDAYKDQIKALVEGGSHIIFIETIFDSLNARAGIYAYKEYRPLPLFISGTIIAGRTLSGQNTEAFYISMSNAKPMCIG
LNCALGANLMQPFLQRLSQIAPTNVHAYPNAGLPNA-MGG---YDETPEMFGEAIRKYAEDGINMVGGCCGTNPDYIREVKRVVDSFPPRQIPEK--SNL
TMLSGLTEFKFTPNIPFINVGERCNIAGSILFKKMIEKEDYEAALKVAKDQVQNGAQILDINLDDGMIDGVSTMIKFCRLLQSIANIPMMIDSSKFEVIE
AGLQNCQGKCVVNSISLKEEDFLHKARIILKYGAAVIVMAFDEQGQATEVENKVSICKRAYKLLEEVGFPPEDIIFDLNILTIATGMPEAANFIDAAEIV
RKECHVHVSGGLSNLSFSFDLREEMHSVFLYYAISKGMDMGIVNAGKLPLYEDIKLTHVILNRTEDHVEQLIEYAKLEKQRGGG-QQKEKKQDEWRVIER
LKHALIKGVIDYIDLDVEEAR----RPLHVIEGPLMEGMGVVGDYFGSGKMFLPQVIQSARVMKKAVNYLVPFMEAE--GE-NGTVLLATVKGDVHDIGK
NIVGVVLGCNNYKVIDMGVMCQCKDIIERARLEKADIIGLSGLITPSLDEMVFNAKEFTKHGINVPLLIGGATTSKKTAVKIEPALYVLDASRAVVVVNN
LL-
>tr|E9C2V3|E9C2V3_CAPO3 5-methyltetrahydrofolate-homocysteine methyltransferase OX=595528 OS=Capsaspora owczarzaki (strain ATCC 30864). GN=CAOG_02686 PE=3 SV=1
---LDRELRE-RILVLDGAMGTMIQRHRLSEKGNNDILVLTRPEIIYDIHRKYLEAGADFIETNTFSATVIAQEDGLWAYKINVEAAKLAKRACDVPRFV
CGAIGPTNRTCS-ERSTNFDTLVPAYKEQAQGLLDGGADVLLIETIFDTLNCKAALFAIETLRRVPIFISGTIVSGRTLSGQTGEAFVVSITHGEAICVG
LNCALGASEMRPFVESLAKATPAYTICYPNAGLPNT-FGG---YDETPEMMAEKLQEFAKSGVNLVGGCCGTTPDHIRAIANAVRGIAPRVPNKT--QDT
LLLSGLEPTRINKLTNFVNIGERCNVAGSRRFAKLIANGNYEEALAIAKSQVEMGAQVLDINMDEGMLDSKFAITKFVNFIASIARVPLCVDSSNFAVVE
AGLKCAQGKCIVNSISLKEAEFIRKARIVKRFGAACVVMAFDETGQAAEADRKLEICARSYDLLPKVRFNPNDIIFDPNILTIATGIEEGVEFIEATRRI
KQRCGARISGGVSNLSFSFVIRESMHSVFLFHAIRAGMDMGIVNAGMLPLYDDIPCEAAVLNTDPNCTEKLLAYAQAK---GKDAGKKAVEDEAWRVESR
LEHSLVKGIDKHVALDVEEARLNEKRPLHIIEGPLMRGMSVVGDLFGAGKMFLPQVIKSARVMKKAVAHLIPFMEAERLEATSGTIVLATVKGDVHDIGK
NIVNVVLGCNNYRVIDLGVMTPCDKILETAIAENADVIGLSGLITPSLDEMIHVAKEMERRGMKLPLLIGGATTSRTTAVKISPAIHVLDASKSVVVVSA
LL-
>tr|F2TYS4|F2TYS4_SALS5 Methionine synthase OX=946362 OS=50818 / BSB-021)). GN=PTSG_01727 PE=3 SV=1
---LRALLEE-RIMFFDGGMGTMIQQLSLQEQGNNDLLVLTQPEAIVNIHKQFLLAGADFVETNTFSSTRIAQADATHVYKLNVEAAKLAKRACEERKFV
AGSLGPTNRTLSPLRNVKFDELVEAYAEQARGLMDGGVDVLLVETIFDTANAKAALFAVEKLPRRPIFISGTITSGRTLSGQTAEAFSISVSHGRPMALG
LNCALGATDMRPYLEEIAKTTDAYIICYPNAGLPNA-MGG---YDETPDITGSHLADFARSGVNIVGGCCGTTPAHIAAIVKMCSSFPPRQRPPK--PDH
MLLSGLEPARIGPDTNFVNIGERCNVAGSRRFCRLIKTDEYDEALAVAKLQVENGAQILDINMDDGLLDGVKAMTKFCNLIASIAKVPLCIDSSDFAVVE
AGLKCTQGKCIVNSISLKEEEFIKVARTIRRYGAAVVVMAFDEKGQAADLEGKIRICTRSYKILEKVGFNPNDIIFDPNILTIGTGIEEAINFINCIRPI
KEQCGCHISGGVSNLSFSFVVREAMHSVFLYHAIQKGMDFGIVNAGAMPIYSEIDCENIIWNKHPNATEELLTYAQEH---GKEA-KTKKQDDSWRVEKR
LEHALIKGIDKFVVADTEEARQNALKPLNVIEGPLMAGMSIVGDLFGAGKMFLPQVIKSARVMKKAVAHLIPFMEEEREDESNGTVVIATVKGDVHDIGK
NIVAVVLGCNNFKVVDLGVMVPANKILEAVDKHKADIVGLSGLITPSLDEMVFVAKELERTGHKLPLLIGGATTSKMTAVKIAPTVHVLDASRSVVTVSA
LL-
>sp|Q54P92|METH_DICDI Vitamin-B12 dependent methionine synthase OX=44689 OS=Dictyostelium discoideum (Slime mold). GN= PE=3 SV=1
---IRKILSE-RIMVLDGAMGTEIQKFKLKDGGNNDLLSLTQPHIIREIHCKYLEAGADFIETNTFNGNIFSQADKMLVKRINIESARLAKSACEEPRFV
CGAVGPTNKTASPARNVLFDELVSGYLEQVEALVEGGIDVILVETVFDSLNCKAALFAIEEFPRLPVFVSGTIVSGRTLSGQTGEAFYTSVASANLMVFG
LNCALGAQEMRPFLQNISKCSECYVSCYPNAGLPNT-FGG---YDETPEMMAEQIKEFAESGLNIVGGCCGTSPDHIRAFCNAIEGIAPRAIPTL--VPN
TTLSGLEPLVFTKELNFVNVGERCNVSGSRRFANLIKANKYEEALSVARQQVEAGAQIIDINMDEGMIDAVAAIQKFLFFIGSISKVPIMLDSSNFDVVE
AGLKCVQGKCIVNSISLKEELFIKQAKIVKQYGASVVVMAFDENGQATSKEEKVRICYRSYKILEQVGFYPQDIIFDPNILTIATGLEEGVEFIEATREI
KALMLTRVSGGVSNLSFSFPLREAMHSAFLYYAIAAGMDMGIVNAGALPIYDDIPVEDAILNRTNDATEKLLEYAQANNKS-----KANVEVEEWRVSER
IAHALVKGITTYIIEDTEEARNT--SSLSVIEGPLMGGMNVVGDLFGAGKMFLPQVIKSARVMKKAVAHLIPFMEEEKREPDAGVVVLATVKGDVHDIGK
NIVGVVLGCNNYKVIDIGVMTPCEKIVEAIIANKADVVGLSGLITPSLDEMIYVASELERLKFKIPLMIGGATTSQITAVKISPTVHVLDASRSVTVVQS
LL-
>tr|D2UYB1|D2UYB1_NAEGR 5-methyltetrahydrofolate-homocysteine methyltransferase OX=5762 OS=Naegleria gruberi (Amoeba). GN=NAEGRDRAFT_34723 PE=3 SV=1
---LEEIFKE-RILIIDGAMGTMIQKYKLSEKGNNDMLCITRPEIIVEIHEKYLEAGADIIETNTFSSTVISQADNALAYRLNFCAAQCAKKAATKPRFV
AGALGPTNKTGSPFRNISFDELYEAYFEQVRGLVDGGADILLIETIFDTLNAKAAAFACMDYIDMPIIISGTITTGRTLSGQTTEAFYISMMHSNMLCMG
LNCALGTVQMKPFVKALSNIAECFTHAYPNAGLPDE-MGQ---YRQTPEEMARQVKDFLDEKVNMIGGCCGTTPDHIRALAQLAAQYKPRKPQEP--THD
MKLSGLEPMIYSKNSNFINVGERCNVAGSIRFKKLIMENKFEDALSIARNQVEAGAQVIDVNMDEGLLDSKNVMKKFLYLIMSISKIPIMVDSSKFEVVE
QGLKCIQGKCIVNSLSLKEEDFIAKAKKVKKYGAAVVVMAFDEQGQAAECARKVEICTRAYKILEKVGFPPEDIIFDPNILTIATGIEEGVEFINTIKII
KETLYAKVSGGVSNLSFSFLVRESMHSAFLYHAIKAGMDMGIVNAGALPIYDEITCEDAILNRNENATENLLSFAQAHGED-----EGPKQKEAWRVQER
LKHALIKGIVDFIDSDVEEAR--QNSPLSVIEGPLMNGMNVVGDLFGAGKMFLPQVIKSARVMKKAVKYLIPYLEKDKETSSAGRILLATVKGDVHDIGK
NIVGVVLACNNFEVIDLGVMIPPDVIVREAKEKNVDIVGLSGLITPSLDEMATVAKEMQKGGLTCPLLIGGATTSRTTAVKICPCIHVLDASRSVVVASS
LL-
>tr|A4RUZ2|A4RUZ2_OSTLU B12 dependent methionine synthase OX=436017 OS=Ostreococcus lucimarinus (strain CCE9901). GN= PE=3 SV=1
-------MQK-RVMVIDGAMGTAVQKYKLSEKGNNDILVLTKPEVISEIHEAYLAAGADIIETNTFSSTMIAQADELEVRDMNLAAARLAKAACVKPRFA
AGAIGPTNRTLSPFRACTFDEIVDAYYEQIEALVEGGVDLILVETIFDTLNAKAAIFAIEKFTRLPLFISGTIVSGRTLSGQTNEAFWNSVSHAKPMAVG
LNCALGAKDMVPYIENLSKCADCWVFAYPNAGLPNA-MGG---YDQKGAEMAEDCRVFLEKGLNGIGGCCGTTDDHIGALAQMVAPYTPRKKHDV--PEI
MRISGLEPFNYVPRKTFINLGERCNVAGSSIFKKAIVDGNFEKALAIALKQVEHGAHVIDINMDDGLIDGETAMSRFVNLLVSASKVPFMIDSSKFHVVE
AGLKCSQGKCIMNSISLKEEEFLHHAKIVKRHGAAVVVMAFDEEGQAATEAEKVRICCRAYKLLEQLGFNPQDIIFDPNILTIGTGMEEGVDFINATREI
KRLCGCKISGGVSNLAFSFPVRRAFHSAFLYHACKAGMDMGIVNAAQVEVYEKMDVEDVLLNRCTNATERMLEFAKSTPCNGGGAVKAAGSGKEWRCEKR
LEYALIKGIDEFCIADTEECRVGDKSCLEVIEGPLMDGMNVVGDLFGAGKMFLPQVIKSARVMKKAVGHLIPFMDAEKAEASAGTFLIATVKGDVHDIGK
NIVAVVLGCNNFKVIDIGVMCPCEKILDAVRESKADILGLSGLITPSLDEMVTVAKEMEKAGMRIPLLIGGATTSKMTAVKLTPVIHVLDASRAVPVAQT
LL-
>tr|Q4QIT5|Q4QIT5_LEIMA Putative methionine synthase OX=5664 OS=Leishmania major. GN=LMJF_07_0090 PE=3 SV=1
---LEELFQK-RILVLDGGMGTMLQRYKLEEKGNNDLLCLTQPAKVRDVHYKYAIAGADVVETNTFNSQAVSQSDETLVRRINLAAAKICRDAAEQRIFV
AGVLGPLNRTASPYRNITYDEIVAAYTEQATALLDGGVDVLLIETIFDSLNAKAALFAVNTLTRLPIMVSGTITSGRTLSGQTVDAFYSSMRHGNIISIG
LNCALGCREMRPYVERLAEISEGYVTCHPNAGLPNA-MGE---YDELPEDMARDIRDFAANGVNLVGGCCGTTPDHIRAIATAVKGIPPRPRGHS--SET
MVISGLEALHFTHHIGFCNIGERCNISGSLKFKRLVKEGKWEECLAVARQQVEEGAMVLDVNMDDGLIDGVTAMTRFLNMIASVARVPVMIDSSKFHVIE
AGLKCTQGTPIVNSISLKEEEFLRQARLIRRYGAAVVVMAFDENGQAADDANKTRICKRAYDML-ADGFPPENIVFDPNVLTICTGMEEAIDFMNAATWI
KANLRAKVSGGISNLSFSFAIRMAMHSAFLKKMIADGLDMAIVNAGALPVYTDIEVEDAIYNRTPHSSERILEYARLKAEKGAEE-AKVSKVDEWRVEER
LSHALIKGIVEFIEDDVEEARTCGKRPLHIIEGPLMGGMGKVGELFGSGKMFLPQVIKSARVMKKAVAVLVPYMEAEKAASTAKRVLMATVKGDVHDIGK
NIVGVVLGCNSYEVLDLGVMVSCEKILAAAREHDVDVIGLSGLITPSLDEMVHVAKEMKRMGFNIPLMVGGATTSKQTAVKIQPTVHVLDASKAVVTVSN
ML-
>tr|B8C9X1|B8C9X1_THAPS 5-methyltretrahydrofolate-homocysteine s-methyltransferase OX=35128 OS=Thalassiosira pseudonana (Marine diatom) (Cyclotella nana). GN= PE=3 SV=1
-------------------MGTMIQNYRLEEKGNNDQLSITQPHIISGIYKEYLEGGSDLIGTNTFSSTTIAMADEMYVYELNYEGARLAREACDEPRFV
VGAIGPTNRTGSPARNVTFDELVEAYFEQIVALMDGGSDILMVETIFDTLNAKAALYAVGEYLDIPVFVSGTLVSGRTLSGQTGEAFYASIRHAKPMCVG
LNCALGANHMVPFVEKLANCVECFLHVYSNAGLPNA-MGG---YDETPDMMAIQNKVFFENGLNMVGGCCGSTPPHIKAIREMSEGYKPRKLPDV--GPK
MWLSGLEDLVVDDGLPFLNVGERCNISGSIRFKKLMMAGDYGTAMDIAKKQVEDGAHVIDINVDDGMLDGLAAMQKFVKIAVTVAKVPFMLDASKFEIVL
AGLKWCQGKCIVNSISLKEELFKEQATLLKKHGCAVVVMAFDEEGQAATEDEKVRICKRSYDILNEVHFPPEDIIFDPNVLTIGTGMEEGVDFINATKTI
KEICYVKISGGISNLSFGFKIRESIHSVFLQHAIESGMDVGIVNAHEMLALSELECENLVFNKTPDATDVMLELTKRERARPAAA---EVKQTSWRVIKR
LEHALINGISQYIDGDVEEARQQVEKPLHIIEGPLMDGMNIIGDLFGAGKMFLPQVIKSARVMKKAVAYLIPFMEKEKRDDSAGKVLMATVKGDVHDIGK
NIVAVVLGCNNYKVYDIGVMCSCEKILEKAKEYNVDVIGLSGLITPSLDEMVVVAKEMSKAGFKQPLLIGGATTSKMTAVKVSPVIHVLDASRSVTVVSS
LL-
>tr|B7GBG7|B7GBG7_PHATC Methionine synthase OX=556484 OS=Phaeodactylum tricornutum (strain CCAP 1055/1). GN= PE=3 SV=1
-------------------MGTMIQNYRLDEKGNNDMLSISQPHIIKGIYMQYLEGGSNMIGTNTFSSTTIAMADQMYAYELNYVGARLAREACDEPRFV
VGAIGPTNRTCSPARNVTFDELVETYLEQVVGLVDGGADVLMVETIFDTLNAKAALYAIGEFLDIPVFVSGTLVSGRTLSGQTGEAFYVSIRHAKPMCVG
LNCALGAKHMVPFVERLSKAAECFVHVYSNAGLPNA-MGG---YDDTPEDMARENEVFFENGLNMVGGCCGSTPPHIKAIRETAERYQPRKLPDV--GPK
MWLSGLEDLKVEDGLPFLNVGERCNIAGSIKFKKLMMKGDYGAAMDIAKQQVEDGAHVIDINVDDGMLDGLAAMQKFVKIAVTIAKVPFMLDASKFDIVM
AGLKWCQGKCIVNSISLKEELFMEQATLLKKHGAAVVVMAFDEQGQAATEDEKIRICKRSYDVLNKVGFPPEDIVFDPNVLTIGTGMEEGVDFINSVKRI
KEECYVKISGGISNLSFGFKIRESIHAVFLHHAIESGMDVGIVNSHELLSVDDLECENLVFNKTPDATDDMLERTNFERSKGVVD---EVKKSSWRPSKR
LEHSLVNGISEFVDSDVEEARVLATKPLDVIEGPLMDGMNVVGDLFGAGKMFLPQVIKSARVMKKAVAYLLPFMDAEKRDDSAGKVLMATVKGDVHDIGK
NIVAVVLGCNNYKVYDIGVMCSCEKILAKAKEYNVDVIGLSGLITPSLDEMVDVAKEMSKQGFKQPLLIGGATTSKMTSVKIAPTIHVLDASRSVTVVNS
LL-
>tr|A8HYR2|A8HYR2_CHLRE Cobalamin-dependent methionine synthase OX=3055 OS=Chlamydomonas reinhardtii (Chlamydomonas smithii). GN= PE=1 SV=1
-------MRE-RIIFIDGAMGTQIQKFTLEEKGNNDLLVITRPDVISKIHTAYLEAGADIIETNTFNGTWISQSDELDVALINRTAAQLAKKCVADPRFV
AGAIGPTNKTLSPFRGITYDEVVDAYYKQAEALVEGGVDMFLVETIFDTLNAKAAMYALEKFMRLPVFVSGTIVSGRTLSGQTNEAFWNSIRHAKPMAVG
LNCALGAKDMLKYVANLAACADCYVFCYPNAGLPNA-MGG---YDQKGDEMAEEIRPFCEGNVNAIGGCCGTGPEHIAAIKKMASAYKPRKPVTV--PPL
MRLSGLEPLNYTPRRTFLNIGERCNVAGSILFKKAIVNNDFDTAVAIALKQVQQGADVLDINMDDGLIEGVGAMTRFVNLLVSISRVPFMIDSSKFHIVE
AGLKCSQGKCIVNSISLKEAAFRHQAEVVRRHGAAVVVMAFDEQGQAASYEEKIRICSRAYRILEEVGFDPQDIIFDPNILTIGTGLPEAVDFIRATREI
KRLCGSKVSGGVSNIAFSFAVRRAFHSAFLHHACLAGMDMGIVNAAQVKEYSKIDVEDVLLNRCENATERMLEYAKSKPT---------AKEESWRVEKR
IEYALIKGIDEFAVVDTEEARSSGRKPLQVIEGPLMDGMNVVGDLFGAGKMFLPQVIKSARVMKKAVAHLIPFIEEEKRENSAGCFLIATVKGDVHDIGK
NIVSVVLGCNNFKVIDMGVMTPWEKILDAAVEHKADIIGLSGLITPSLDEMVTVAKKMEERGMKTPLLIGGATTSKMTAVKIAPVVHVLDASRSVPVCQA
FV-
>tr|D3BM55|D3BM55_POLPA Cobalamin-dependent methionine synthase OX=13642 OS=Polysphondylium pallidum (Cellular slime mold). GN= PE=1 SV=1
-------------MILDGAMGTEIQKFKLKDGGNNDLLVLTQPHIIKEIHKKYLEAGADIIETNTFNGNIFSQADKMLVKRINREAARIAKEAAQEPRFV
AGAVGPTNKTASPARNVLFDELVDGYFEQVEALVEGGIDILLVETVFDSLNCKAALFAIENFPRIPVFVSGTIVSGRTLSGQTGEAFYTSTAHADPMVFG
LNCALGANEMRPFLQNISKCAECFVLCYPNAGLPNT-FGG---YDETPEMMAVQIQEFAESGLNIVGGCCGTSPDHIREFARVTKGVQPRQIPSL--PPY
TTLSGLEPLAFTPTLNFVNVGERCNVSGSRRFANLIKANKYEEAISVARQQVEAGAQIIDINMDEGMIDAVAAIQKFLFFIGSISKVPIMLDSSNFAVVE
AGLKCVQGKCIVNSISLKEELFMEQARICKQYGASVVVMAFDEQGQATSKEEKVRICYRSYKILERVGFKPQDIIFDPNILTIATGLEEGVEFIEATREI
KRLMLTKVSGGVSNLSFSFPLREAMHSAFLFHAIKAGMDMGIVNAGQLPIYDDIEVEDAILNRTNDATERLLEHAQKNAKT-----KATTEVEEWRVSSR
ITHALVKGITNFITEDTEEARNT--SSLSVIEGPLMSGMNVVGDLFGAGKMFLPQVIKSARVMKKAVAYLIPFMEEEKAEAEAGVCVLATVKGDVHDIGK
NIVGVVLGCNNYKVIDLGVMCPCEKILAAAIEHKADIVGLSGLITPSLDEMIYVASEMERMKFKVPLLIGGATTSQITAVKIAPTVHVLDASRSVTVVSS
LL-
>tr|L1J673|L1J673_GUITH Uncharacterized protein OX=905079 OS=Guillardia theta CCMP2712. GN=GUITHDRAFT_159764 PE=4 SV=1
-------------MVIDGAMGTVIQ------KGNNDLLSLTRPDVINEIHRRYFDAGADICETNTFSGTTVAQADGLLVPEINYKSAKLCKMAAEVRRFC
AGAVGPTNRTLSPFRNITFQELVTAYKDQVKSLVEGGCDLLFVETIFDTLNAKAALFAIDVFVKMPIVISGTIVSGRTLSGQTTEAFWVSVSHAQPLCVG
LNCALGPDQMRPFMTRLSNVATCFTHAYPNAGLPNA-MGG---YDLNPADMAPKLREWAKDGVNLVGGCCGTTPDHIKAIADAVADVKPCRVIPE--PNK
MRLSGLEDLTVDKSLNFANIGERCNVAGSIRFKKLIIANDWAKAAEVAQKQVEDGAQLVDINFDDGMLDGVDCMKKFCNLIATIAKVPMVIDSSKFHICI
AGLECLQGKCIVNSISLKEEEFKQQAKLIKRYGAAVIVMAFDEQGQAAGYEDKVRICQRAYKILEEVKFNPFDIVFDLNILTICTGLEEGVDFINATKTV
KETCGAKISGGLSNLSFSFSIREAMHGVFLYHAIKNGMDMAIVNAGNLPIYDDIECEDAILNRSSEATEKMLELAEKEKQRGGD--KVKKAAAEWRVKGR
LIHALIKGLDEFIEADVEEARVDDAAPLNIIEGPLMEGMNIIGDLFGAGKMFLPQVIKSARVMKKAVAYLTPFMEEEKAVQK-GCVLIATVKGDVHDIGK
NIVAVVLGCNNYEVIDMGVMCPCEKILDKAQEVGADVIGLSGLITPSLDEMVTVAKEMQRRNMKVPLLIGGATTSRMTAVKIEPVIHVLDASRAVSVVSS
LL-
>tr|D7FUT0|D7FUT0_ECTSI Methionine synthase OX=2880 OS=Ectocarpus siliculosus (Brown alga). GN= PE=3 SV=1
-------------------------------KGNNDMLSITQPHIIKEIHTKYVDSGSDIIATNTFSATTIAMADEMDVYELNFESARLAREACEEPRFV
MGALGPTNRTGSPFRNVTFDELVVAYKDQTKGLIDGGADIIIVETIFDTLNAKAGVFAVREYIDVPLFVSGTLVSGRTLSGQTTEGFYVSMRHCKPFCIG
LNCALGASQMRPFLQRLAKVAECFVHVYSNAGLPNA-MGG---YDETPEDMARDNLLFAEEGINMLGGCCGSTPAHIKAMKDAVEPCSTRALPPP--RPF
MWLSGLEDLIVTK-FQFLNVGERCNVSGSIRFKKLILKGDYQTAMDVAKQQVEDGAMVIDINLDDGLLDGMAAMQKFCKIAVTVSKVPFMIDSSKFPIVE
AGLKWVQGKSIVNSISLKEEEFKRHARIVKAHGAAVVVMAFDEEGQAADCDNKVRICKRSYDMLDEVGFPPEDIIFDPNILTIATGIDEAVDFIQATERI
KEICYCKISGGVSNLSFGFVIRESMHSVFLFHAVKAGMDMGIVNAGMLEVYDDIEVEDAVNNRHSGATEALLDAAEIEKEKKGKG---TVEASGWRVQER
LTHSLIKGIDQWVIEDVEECRLMLDRPLDVIEGPLMSGMNVVGDLFGAGKMFLPQVIKSARVMKKAVAHLLPFMEAEKLDDSAGKVLIATVKGDVHDIGK
NIVAVVLGCNNYKVYDMGVMQPCDLILAKAKQLKVDVIGLSGLITPSLDEMVFVAKEMAKGGFKLPLLIGGATTSKMTAVKISPVIHVLDASRSVTVVGA
LL-
>tr|I1CCM8|I1CCM8_RHIO9 Methionine synthase OX=246409 OS=43880) (Mucormycosis agent) (Rhizopus arrhizus var. delemar). GN=RO3G_10919 PE=3 SV=1
-------------MFLDGAMGTMVQRLKLEERGNNDLLTLTKPDAIYHIHRQYLEAGADMIETNTFSSTSIAQLDSLYAYRLNKEGAALAKKACED-RFV
CGAIGPTNRTCSPYRNVTFDELVTAYSEQVRGLLDGGSDILLVETIFDTLNAKAAIFAILVFPKVPIFISGTIVSGRTLSGQTGEAFVTSLNHARPVAFG
LNCALGAEQMKPFVQNISRFTDAHIICYPNAGLPNA-MGE---YDESPEAMAKNVEPFAKEGVTIVGGCCGTTPDHIKAVAEVCRQYSPRKPASK--QDV
MLLSGLEVLRVNETTGFVNVGERCNVAGSRKFCRHILKNEYEEALAIARAQVESGAQVVDVNFDEGLLDGKAAMTKFLNMLASCARVPLMVDSSNFAVIE
AGLRCAQGKCIVNSISLKEEEFIKKAKIIKRFGAAVVVMAFDEVGQAAEADRKVEICTRSYRILDKVGFNPYDIIFDPNILTIATGMEEAVEFIQACETI
KKTLGAKVSGGVSNLSFAFKVREAMHSVFLYYTVKVGMDMGIVNAGFLTVYDDIPCEDAVWNRDPDVTEKLLEYAKAHSKD-----KKDEDQEEWRVTER
ITHALVKGIMKFIVEDTEEARSDEKRALNVIEGPLMTGMNVVGDLFGKVHVMI------ISVMKKAVAHLVEYIKLEKEEIKNGTIVMATVKGDVHDIGK
NICGVVLGCNNYRVIDLGVMVPCDKIIKTAIEEKADVIGLSGLITPSLEEMVIVAKECEKAGIKIPILIGGATTSKMTAVKIAPAIYVLDASRSVPVVAS
LL-
>tr|F4PVY7|F4PVY7_DICFS Cobalamin-dependent methionine synthase OX=1054147 OS=Dictyostelium fasciculatum (strain SH3) (Slime mold). GN= PE=3 SV=1
---LRKILDE-RIMILDGAMGTEIQKYKLKDGGNNDLLVLTRPHIIKEIHLKYLLAGADIIETNTFNGNIFSQADKMLVKRLNIEAAKLAKDACIEQCYV
AGAVGPTNKTASPARNVKFDELVDGYYEQVEALVEGGIDIILVETVFDSLNCKAALFAIENYTVLPVFVSGTIVSGRTLSGQTGEAFFTSVQHARPMVFG
LNCALGATEMRPFLANVSKCSDCYVSCYPNAGLPNT-FGG---YDETPEMMAGKILEFAQSGLNIVGGCCGTSPDHIRAFVEATRGVQPRRIPTI--APY
TTVSGLEPLAFTPQLNFVNVGERCNVSGSRRFANLIKANKYEEAISVARQQVEAGAQIIDINMDE-----------------------------------
-------GKCIVNSISLKEELFIEQARICHQYGAAVVVMAFDENGQAVDKNDKVRICYRSYKILEVVGFKPQDIIFDPNILTIATGLEEAVEFIEATREI
KQLMLTKVSGGVSNLSFSFPLREAMHSAFLFHAIRAGMDMGIVNAGALPIYDDIDCEDAILNRSNDSTERLLEYAQRSKGS-----GAAAEVEEWRVQER
ISHALVKGITSHIIEDTEEARLT--SALRVIEGPLMSGMDVVGDLFGAGKMFLPQVIKSARVMKKAVAHLIPFMEEEKLDQEAGVVVLATVKGDVHDIGK
NIVGVVLGCNNYKVIDLGVMTPCEKILQQAIEQKADIIGLSGLITPSLDEMIYVASEMQRAGFKVPLMIGGATTSQITAVKISPVVHVLDASRSVTVVSS
LL-
>tr|D0MU48|D0MU48_PHYIT Methionine synthase OX=403677 OS=Phytophthora infestans (strain T30-4) (Potato late blight fungus). GN=PITG_01804 PE=3 SV=1
---LTALMKQ-RTLIFDGGMGTMIQVHKFTEKGNNDLLSITQPHIIKEIHKQYMQGRAQLIGTNTFSGTTIAQADQMLVYELNYESAKLAREAADEPRFV
AGSIGPTNRTLSPFRNVTFDELVDAYYTQVEGLVDGGSDVLLVETIFDTLNAKAAVFAINKYRKLPLFISGTIVSGRTLSGQTTEAFYVSLRHSKPFCIG
LNCALGANQMKPFLQRLANVAECFVSVYANAGLPNA-MGG---YDDTPAMMAEYCEEFSKDRVNMMGGCCGTTPQHIQAIAKMTTKYDPRPLPEL--KPF
MWLSGLEDMVVTK-FSFLNVGERCNISGSIRFKRLIMKSDYGTAMDVARQQVEDGAMVIDVNVDDGMLDGVAAMERFLKIAVTVSKVPFMIDSSKFHIVE
AGLKCVQGKCIVNSISLKKELFMEHARIVKNHGAAVVVMAFDEEGQAATEAEKVRICKRSYDILNEVGFPPEDIIFDPNILTVATGMEEGVDFINACRII
KEQNYC---------------------------------------------------------------------------GAVA---AANKQEWRIGER
LTYSLVKGISEFIDQDVEEMRKVADKPLDVIEGPLMDGMNVVGELFGSGKMFLPQVIKSARVMKKAVAYLLPFMEEEKNEDSAGKVLIATVKGDVHDIGK
NIVGVVLGCNNYKIIDLGVMVPCENILAAAKEYNVDVIGLSGLITPSLDEMVHVAREMSKAGLNIPLIVGGATTSKMAAVKIAPVMHVLDASRSVVVVGN
LL-
>tr|K8DSZ8|K8DSZ8_9ENTR 5-methyltetrahydrofolate--homocysteine methyltransferase OX=1074000 OS=Cronobacter universalis NCTC 9529. GN=BN136_2195 PE=4 SV=1
---LHRQLAE-RIMVLDGGIGTMIQSYRLDEGENNDLLVLTKPDIIAAIHYAYFEAGADIIETNTFNSTTIAMADQMLSAEINYEAAKLARACADEPRYV
AGVLGPTNRTISPFRNITFDQLVDAYRESTRALIEGGSDLILIETVFDTLNAKAAIFAVKAEFELPIMISGTITSGRTLSGQTTEAFYNSLRHADALTFG
LNCALGPDELRQYVAELSRIAECYVTAHPNAGLPNA--FG--EYDLDADVMAAQIREWAESGLNIVGGCCGTTPEHIAAMSRAVEGLPPRKLPD--IPVA
CRLAGLEPLNIGDDSLFVNVGERTNVTGSAKFKRLIKEEKYSEALDVARQQVENGAQIIDINMDEGMLDAEAAMVRFLNLIAGIARVPIMIDSSKWDVIE
KGLKCIQGKGIVNSISMKEGAFVHHAKLVRRYGAAVVVMAFDEVGQADTRERKIEICRRAYQILEEVGFPPEDIIFDPNIFAVATGIDEAQDFIGACEDI
KRELHALISGGVSNVSFSFPVREAIHAVFLYYAIRNGMDMGIVNAGQLAIYDDLPTEDVILNRRADGTERLEKYRGKADSA----ADAQQAERSWDVKKR
LEYSLVKGITEFIEQDTEEARQQAERPIQVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAYLEPYIQASKVGKSNGKIVLATVKGDVHDIGK
NIVGVVLQCNNYEIIDLGVMVPTDKILKTAREVNADIIGLSGLITPSLDEMVNVAKEMERQGFTLPLLIGGATTSKAHAVSG-PTVYVQNASRTVGVVSS
LL-
>tr|F0KGC3|F0KGC3_ACICP Methionine synthase OX=871585 OS=Acinetobacter calcoaceticus (strain PHEA-2). GN= PE=3 SV=1
---LKALLAK-RILIIDGAMGTMIQRHKLEEGENNDLLVLTQPQIIQGIHEAYLDAGADIIETNSFNGTRVSMSDHMLVPEINREAARLAK--AACPRFV
AGVLGPTSRTISPFRNITFDELKENYIEATHALIEGGADIILIETVFDTLNCKAAIFAVKEVFELPIMISGTITSGRTLTGQTAEAFWNSVRHGDLLSIG
FNCALGADAMRPHVKTISDVADTFVSAHPNAGLPNA--FG--EYDETPEQTAAFLKEFAESGINITGGCCGTTPDHIRAIANAVKDIAPRQVPE--TVPA
CRLSGLEPFNIYDDSLFVNVGERTNVTGSKKFLRLIREENFAEALEVAQQQVEAGAQIIDINMDEGMLDSQNAMVHFLNLVASISRVPIMIDSSKWEIIE
AGLKCVQGKPVVNSISLKEDEFVEKARLCRQYGAAIIVMAFDETGQADTAARKREICKRSYDILNDVGFPAEDIIFDPNVFAVATGIEEGVDFIEATGWI
KQNLHAMISGGVSNVSFSFPVREAIHSVFLYHAIKQGMTMGIVNAGQMAIYDDIPAEDVILNQNQGATEKLEKYRGQGGAT----KEAENLERNESVEKR
LEYALVKGITTYIDEDTEEARLKAKRPLDVIEGALMDGMNVVGDLFGSGKMFLPQVVKSARVMKQAVAWLNPYIEAEKGSQSKGKVLMATVKGDVHDIGK
NIVGVVLGCNGYDIVDLGVMVPCEKILQTAIDEKCDIIGLSGLITPSLDEMVFVAKEMQRKGFNIPLLIGGATTSKAHAVQNDAVIYVADASRAVGVATT
LL-
>tr|K2PG38|K2PG38_9RHIZ B12-dependent methionine synthase OX=1156935 OS=Agrobacterium albertimagni AOL15. GN= PE=3 SV=1
---LQEAARE-RILILDGAMGTEIQGLGLTEGENNDLLILTQPNAIEDIHFRYAMAGADILETNTFSSTRIAQADEMAVYDLNRHGAELVRR-AAWRRFV
AGAIGPTNRTISPYRAVSFDDLRLAYGEQIDGLIDGGADLILIETIFDTLNAKAAIFACEERFRLPVMISGTITSGRTLSGQTPTAFWNSIRHAKPFAVG
LNCALGADAMRPHLQELSGVADTFISAYPNAGLPNE--FG--RYDQSPEEMADLVAGFAEEAVNVVGGCCGSTPAHIAAIAEAVKGRAPRAPAE--HRPF
MSLSGLEPFELTKDIPFVNVGERTNVTGSAKFRKLITAGDYSAALVVARDQVENGAQIIDINMDEGLIDSEKAMVEFLNLIAAIARVPVMIDSSKFPIIE
AGLKCVQGKAVVNSISLKEENFVAQAKLIRNYGAAVVVMAFDEKGQADTYERKVEICRRAYRILEEAGFAPEDIIFDPNVFAVATGIEEGVDFIEATRTI
RQEMLVHISGGVSNLSFSFPVREAMHAVFLYHAIQAGMDMGIVNAGQLAVYESIDPEDVVLNRRRDGTERLERYRGTGEAK----TRTQDMTREWPVEKR
LEHALVNGITEFIDVDTEEARQKADRPLHVIEGPLMAGMNVVGDLFGAGKMFLPQVVKSARVMKQAVAVLLPYMEEEKERQAAGKVLMATVKGDVHDIGK
NIVGVVLACNNYEIIDLGVMVPATKILEVAKAENVDVIGLSGLITPSLDEMVHVAAEMQRQGFNIPLLIGGATTSRVHAVKAGQAIYVTDASRAVGVVSA
LL-
>tr|I0VXY4|I0VXY4_ECOLX Methionine synthase OX=1090926 OS=Escherichia coli W26. GN= PE=3 SV=1
---LRAQLNE-RILVLDGGMGTMIQSYRLNEGENNDLLVLSKPEVIAAIHNAYFEAGADIIETNTFNSTTIAMADQMLSAEINFAAAKLARACADEPRYV
AGVLGPTNRTISPFRNITFDQLVAAYRESTKALVEGGADLILIETVFDTLNAKAAVFAVKTEFELPIMISGTITSGRTLSGQTTEAFYNSLRHAEALTFG
LNCALGPDELRQYVQELSRIAECYVTAHPNAGLPNA--FG--EYDLDADTMAKQIREWAQAGLNIVGGCCGTTPQHIAAMSRAVEGLAPRKLPE--IPVA
CRLSGLEPLNIGEDSLFVNVGERTNVTGSAKFKRLIKEEKYSEALDVARQQVENGAQIIDINMDEGMLDAEAAMVRFLNLIAGIARVPIMIDSSKWDVIE
KGLKCIQGKGIVNSISMKEDAFIHHAKLLRRYGAAVVVMAFDEQGQADTRARKIEICRRAYKILEEVGFPPEDIIFDPNIFAVATGIEEAQDFIGACEDI
KRELHALISGGVSNVSFSFPVREAIHAVFLYYAIRNGMDMGIVNAGQLAIYDDLPAEDVILNRRDDGTERLEKYRGKTDDT----ANAQQAERSWEVNKR
LEYSLVKGITEFIEQDTEEARQQATRPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAYLEPFIEASKQGKTNGKMVIATVKGDVHDIGK
--ISLAWCCN----------------------VTTTKLSISALWCL-------------RKKFSVPLKK-------------------------------
---
>tr|J3BB66|J3BB66_9RHIZ 5-methyltetrahydrofolate--homocysteine methyltransferase OX=1144310 OS=Rhizobium sp. CF080. GN= PE=3 SV=1
----------------------------------------------------------------------------------------MAKR-AAFRRFV
AGAIGPTNRTISPYRAVTFDDLRIAYGEQLDGLIDGGADIILIETIFDTLNAKAAIFACAERFRLPVMISGTITSGRTLSGQTPSAFWSSIRHSKPFTVG
LNCALGADAMRPHLQELSGVADTFISAYPNAGLPNS--FG--GYDESPEDMARQIKGFAEEGVNVVGGCCGSTPDHIRAIAEAVAPYKPREVPE--HRPF
MSLAGLEPFEFTKDVPFVNVGERTNVTGSAKFRKLITAGDFTAALAIARDQVENGASVIDINMDEGLIDSQRAMVEFVNLIAAIARVPIMLDSSKFEIME
AGLKCVQGKPVVNSISMKEEKFIAQAKLLRNYGAAVVVMAFDEQGQADTYERKVAICERAYKLLEEADFPPEDIIFDPNIFAVATGIEEGLAFIQATKTI
RERMLVHVSGGVSNLSFSFPVREAMHAVFLYHAIQAGMDMGIVNAGQLAIYENIDPEDVVLNRRDDATERMERYRGTGSKE----AKEKDLAREWPVEKR
LSHALVNGINEFIDIDTEEARQNAERPLHVIEGPLMAGMNVVGDLFGSGKMFLPQVVKSARVMKQAVAVLLPYMEEEKQKKSAGKVLMATVKGDVHDIGK
NIVGVVLACNNYEIIDLGVMVPATKILETAIAEKVDIIGLSGLITPSLDEMVHVASEMERQGFDIPLLIGGATTSRVH----------------------
---
>tr|A0Z416|A0Z416_9GAMM B12-dependent methionine synthase OX=247639 OS=marine gamma proteobacterium HTCC2080. GN= PE=3 SV=1
---LIDALEQ-QILLIDGAMGTMIQEQVLTEGENNDLLSLTRPNLISTIHETYLAAGADLIETNTFNATATAQADQLIIWDLNLEGARLARGAADKPRFV
AGVLGPTPRTISPARNITFDELRADYQLATEALIEGGVDILMVETVFDTLNAKAALFGCREAMELPIMVSATFPSGRLLSGQTGEAFWHAIAHARPLIVG
SNCGRRFREVKPFLEELAKVSSCYFSAHLNAGLPNA--FG--DYDETPQDMATDFDTFAAQGLNLAGGCCGTTPEHIRSIATSVADHQPRKLPA--LPQD
TYLSGLESFSFTGKN-FVNVGERCNVTGSARFKSLILDDQYEAALDVARKQVEDGAQIIDINMDEGMLDAEAAMVRFLNLIASIARVPIMVDSSKWSVIE
AGLKCIPGKSIVNSISLKAAEFLQQASLCQRYGASVVIMAFDEDGQADTFERRKKICRRSYDLLSELDFNPFDIMFDPNIFAIGTGIEVAVDFIETARWI
KENLGARISGGVSNVSFSFPVREAIHSVFLYHAIGAGLDMGIVNAGQLAVYDDLPAEDLVLNRKDDATERLEEYRG---SR----SRVEDLTREGPVANR
LQHALLKGITQFIEEDAEEARQLSKRPIDVIEGPLMDGMNTVGD--------------------------------------------------------
----------------------------------------------------------------------------------------------------
---
>tr|K1P5E0|K1P5E0_CRAGI Methionine synthase OX=29159 OS=Crassostrea gigas (Pacific oyster) (Crassostrea angulata). GN= PE=3 SV=1
--KIQSTLQE-RIMIFDGGMGTMIQKHRLEEEGNNDILVLTQPKLVFEIHKDYFEAGADFVETNTFSGTKIAQADGTLTYRLNYEAAKIAKRAAEEQKYV
AGAMGPTNRTLSEFRNVTFDELVEAYTEQAKGLLEGGADVLLVETIFDTANSKAALFAIEEKFTCPVFVSGTIVSGRTLSGQTTEAFLISVSHGNPMCIG
LNCALGANEMRPFIEAVSKNTTAYTICYPNAGLPNT-FGD---YDETPESMCEQLSNFARDGLNIVGGCCGTTPEHIKAIAEGVSQFKPRVPPDELRKDF
MMLSGLEPTYLGPYTNFVNIGERCNVAGSRKFARLIKDGDYEEALSIAKTQVENGAQILDINMDEGMLDGVACMTKFVNLVASESKVPLCIDSSNFAVIE
AGLKCTQGKCIVNSISMKEEDFVEKARKIKQYGAAVVVMAFDEEGQATGRQRKFEICQRSYRILDKVKFNPNDIIFDPNILTIATGIEEGVDFIMATKDI
KENLGARVSGGVSNFSFSFRVREAMHSVFLYHAIKNGMDMGIVNAGCLPVYDDIEPENLLWNKDPDGTEKLLAYAQSMGKD----AKKAVVSDEWRVEER
LEFSLIKGIDKFVVEDTEEARQNQPRPLNVIEGPLMKGMSVVGDLFGAGKMFLPQVIKSARVMKKAVGHLIPFMEKEKESGYSGVIVLATVKGDVHDIGK
NIVGVVLACNNFKVIDLGVMTPCEKILQTAMEENADIIGLSGLITPSLDEMIYVAKEMERIGFKVPLLIGGATTSKTTAVKIAP-QYKLDASKSVVVCSQ
LL-
>tr|C3YH00|C3YH00_BRAFL Putative uncharacterized protein OX=7739 OS=Branchiostoma floridae (Florida lancelet) (Amphioxus). GN=BRAFLDRAFT_122283 PE=3 SV=1
--KIAATLRE-RIMILDGGMGTMIQGYHLEEDGNNDLLSLTQPNIVYDIHKAYLEAGADFAETNTFSGTRIAQADGMLVYRLNKVSAELAKKAADK----
-----------------AWDELVDAYAEQARGLLDGGCDVLMVETIFDTANSKAALFALSQYKPVPIFVSGTIVSGRTLSGQTSEAFVISVSQAEPMCLG
LNCALGATEMRPFIEAIGKNTTSYVLCYPNAGLPNA-LGG---YDETPEIMAEHLRVFAKDGLNLVGGCCGTTPAHIKAIAEAVRPFRPRKVPSVLHEGH
MLLSGLEPMYVGPHTLFVNIGERCNVAGSRAFNKMIQRGDYEKALSVAKHQVEMGAQVLDINMDEGMLDGKAAMARFLNLIATECKVPLCIDSSNFSVIE
AGLKCAQGKCIVNSISLKEEDFLRKARTIRRYGAAVVVMAFDETGQATDVEHKVQICTRSYRLLDKVGFNPCDIIFDPNILTIATGMEEAINFIEATKII
KKTLGCRVSGGLSNLSFSFRIREAMHSVFLYHAIKAGMDMGIVNAGNLPLYDDISEEDLIWNKDPEATEKMLAYAQVHGKG----AKKEQESEEWRVEER
LEHSLVKGIDKYVVEDTEEARANMPRPLNVIEGPLMKGMSIVGDLFGAGKMFLPQVIKSARVMKKAVAYLIPYMEEEKKAKYAGTIVLATVKGDVHDIGK
NIVGVVLGCNNYRVIDLGVMTPCEKILKTAVEENADIVGLSGLITPSLDEMIFVAKEMQRVGLKLPLLIGGATTSKTTAVKIAP-RYKLDASKSVVVCSA
LM-
>tr|E3M453|E3M453_CAERE Putative uncharacterized protein OX=31234 OS=Caenorhabditis remanei (Caenorhabditis vulgaris). GN=CRE_11691 PE=3 SV=1
--ELADIAKE-RIMIIDGAMGTMIQREYMEENGNNDLLSITRPDIIYKIHKLYLEAGADFVETNTFSGTTIAQADRCLVHEINYQSALVARKACDDRRYV
CGAIGPTNRTLSDFRNVTFQELVKAYGDQARSLIQGGVDVLLVETVFDSANAKAALFAIRTGV-EPVFLSGTIVSGRTLSGQTGEAFLVSTKQGSPMAVG
LNCALGAKDMRQFVANMSKWSDTLILCYPNAGLPNA-LGG---YDETPQEMADVLREFARDGVNIIGGCCGTTPDHINAMYKAVQGISPRIPPSDPHAGK
MLLSGLEPSIVGPETNFVNIGERCNVAGSRRFCNLIKNENYDTAIDVARVQVDSGAQILDVNMDDGLLDGPYAMAKFLRLISSEAKIPVCIDSSDFDVII
AGLESTQGKCVVNSISLKEEKFKERARIVKRYGAAVVVMAFDEEGQAAETERKFEICERSYRILEEVGFNPNDIIFDANILTIATGMEEGMYFIEATRMI
RENLGAHVSGGVSNISFSFRIREAMHSVFLFYAIKAGMDMGIVNAGALPVYEDIDKEDLLFNRDPEATEKLLVAAQEMKKD----GKKS-KTDEWRVEER
LKFALVKGIDQFVVADTEEARQNTPRPLNVIERPLMDGMAVVGELFGAGKMFLPQVIKSARVMKKAVAHLLPFMDAERQSPYQGTVVIATVKGDVHDIGK
NIVAVVLGCNNFKVVDLGVMTPCENIIKAAIEEKADFIGLSGLITPSLDEMVHVAKEMSRVGLKIPLLIGGATTSKTTAVKIAP-RYPLDASKSVVVCSS
LS-
>tr|I3JJQ4|I3JJQ4_ORENI Uncharacterized protein OX=8128 OS=Oreochromis niloticus (Nile tilapia) (Tilapia nilotica). GN= PE=3 SV=1
--ELRAVLQQ-RIMVLDGGMGTMIQQQKLEEEGNNDILSITQPDIIYKIHKEYLLAGADIIETNTFSSTSIAQADGLMAYRLNKASAQLARRAADDKRYV
AGAVGPTNKTLSDFRNITFDELVEAYSEQVRGLLDGGVDILLVETIFDTANAKAALFAIDLYDRKPIFISGTIVSGRTLSGQTGEAFVVSVSHAEPLCIG
LNCALGAKEMRPFIEAIGKSTTAFIICYPNAGLPNT-FGG---YDETPQVTASNLKEFAMDGVNIVGGCCGTTPSHIRAISEAVRHCVPRAPAADIYQDY
LLLSGLEPFTVGPHTNFVNVGERCNVAGSRKFAKLIMAGNYEEALSIAKAQVEMGAQVLDINMDEGMLDGPKAMARFCSFIASEARVPLCIDSSNFSVIE
AGLKCCQGKCIVNSISLKEQEFLLRAATVKRYGAAVVVMAFDEEGQATDTERKVEICTRAYQLLNKVGFNPNNIIFDPNILTIGTGMEEAISFITATKII
KETLRARVSGGLSNLSFSFRIREAMHGVFLYHAIKNGMDMGIVNAGNLPVYDDIDKENLIWNRDGDATEKLLAYAQSNAKG----GKQIIRTDEWRVEER
LEYALIKGIEKYVVEDVEECRAQVTRPLHIIEGPLMNGMKAVGDLFGAGKMFLPQVIKSARVMKKAVSYLIPFMEKERQDPYQGTIVLATVKGDVHDIGK
NIVGVVLGCNNFRVIDLGVMVPCDQILRAAVTQKADVIGLSGLITPSLDEMIYVAKEMERLGMTTPLLIGGATTSKVTAVKIAP-RYSLDASRSVVVCSQ
LL-
>tr|H2T6W4|H2T6W4_TAKRU Uncharacterized protein OX=31033 OS=Takifugu rubripes (Japanese pufferfish) (Fugu rubripes). GN= PE=3 SV=1
--ELREILQQ-RIVILDGGMGTMIQQQKLEECGNNDLLSLTRPDIVYKIHKDYLLAGADIIETNTFSGTSVAQADGLMAYRLNRASAELARKAADDKRYV
AGALGPTNKTLSHFRNITFDALVEAYTEQVRGLMDGGVDILLVETIFDTANAKAALFAIDLYKRKPIFISGTVVSGRTLSGQTVEAFVVSVSHANPLCIG
LNCALGATEMRPFIEAIGKCTTAFVICYPNAGLPNT-FGE---YDESPEVTASNLKEFSIDGVNVVGGCCGTTPEHIRALCEAVRMCQPRVPPSDVYQDY
LMLSGLEPFKIGPYTNFVNIGERCNVAGSRKFAKLITSGLCEEALSIAKAQVEMGAQILDINMDEGMLDGVTAMAQFCNLIASDARVPLCIDSSNFSVIE
AGLKCCQGKCIVNSISLKETDFLNKAACVKRYGAAVVVMAFDEQGQATDTDRKVEICTRAYQLLTKVGFKPNDIIFDPNILTIGTGIDEAINFIKATELI
KGTLGTRVSGGLSNLSFSFRIREAMHGVFLYHAIKVGMDMGIVNAGNLPVYDDIDKENLIWSRDSDATENLLAYAQNIVKR----GKKIDHTEEWRVEER
LEYALVKGVDKYVIDDVKECQAQVTRPIHIIEGPLMNGMKIVGDLFGAGKMFLPQVIKSARVMKKAVGYLIPFMEKERQDPYMGTIILATVKGDVHDIGK
NIVGVVLSCNNFRVIDLGVMVPCDKILKEAIVHNADIIGLSGLITPSLEEMIYVAKEMERLRMTIPLLIGGATTSKTTAVKIAP-RYALDASRSVVVCSQ
LL-
>tr|H2Y1G0|H2Y1G0_CIOIN Uncharacterized protein OX=7719 OS=Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis). GN= PE=3 SV=1
--EIESTLQK-RIMIFDGGMGTMIQNLRLEEEGNNDLLSLTKPESIYEIHKAYLEAGADFIETNTFSGTSIAQADALVVYELNYESAKIAKRAARDKRYV
AGSVGPTNKTLSEYRNITFDELVTSYSEQVRGLLDGGADVLLVETIFDTANAKAGLFAIQVYAPLPIFVSGTIVSGRTLSGQTGEAFVVSVSHAKPMCLG
LNCALGAVEMRPFIEVIGNFTDRYVICYPNAGLPNT-FGG---YDETPQTTAKYLAEFAASGVNIVGGCCGTTPEHIRAIANAVKIHKPRVPPHDPHKGC
LLLSGLEPAIISSLTNFVNIGERCNVAGSRRFARLIQNGKYESALDVARSQVEMGAQILDINMDEGMLDGGVVMPKFINLIGSESKVPLCIDSSNFNIVV
AGLKTTQGKCIVNSISLKEEDFVEKAKLILRFGAAVVVMAFDEEGQATSSEDKVRICTRSYRILDQVGFNPNDIIFDPNILTIGTGMEEAIHFINATRII
KQTLGCRISGGLSNLSFSFRIREAMHSVFLFHAITAGMDMGIVNAGNLPVYDDIPAEDLIWNKDPDATEKLLKYAQDYGKS----GSKSVESEEWRVEER
LQHSLVKGIDKYVIEDTKECQQNTPRALNVIEGPLMKGMGVVGDLFGAGKMFLPQVIKSARVMKKAVGYLIPIMEEEKKDRFAGTVVMATVKGDVHDIGK
NIVGVVLGCNNYRVIDLGVMTPCDKILQTALENKADIIGLSGLITPSLSEMIHVAKEMERQDMKIPLLIGGATTSRTTAVKISP-RYNLDASKSVVVISS
LL-
>tr|H2MH00|H2MH00_ORYLA Uncharacterized protein OX=8090 OS=Oryzias latipes (Medaka fish) (Japanese ricefish). GN= PE=3 SV=1
--ELRALLQQ-RILVLDGGMGTMIQQQQLDEGGNNDLLSITRPDVIYKIHKEYLLAGADIVETNTFSSTSIAQADGLMAYLLNRRSAELARKAADDKRFV
AGALGPTNKTLSDFRNITFDELVEAYSDQARGLLDGGADILLVETIFDSANAKAALFAIDLYERRPIFISGTIVSGRTLSGQTGEAFVVSVSHAKPLCIG
LNCALGATEMRPFIEAIGKNTTAFIICYPNAGLPNT-FGG---YDETPEVTASHLKDFATDGVNVVGGCCGTTPSHIRAISEAVKHRQPRVPPTAIYEDY
LLLSGLEPFKIGSHTNFVNIGERCNVAGSRKFAKLILAGHYEEALSIAKAQVEMGAQILDINMDEGMLEGPKAMARFCNYIASEARVPLCIDSSNFAVIE
AGLKCCQGKCIVNSISLKEEEFLLRAATVKRYGAALVVMAFDEEGQATETNRKIQICTRAYTLLNQVGFDPNDIIFDPNILTIGTGMEEAVNFIQATRLI
KETLRARVSGGLSNLSFSFRVREAMHGVFLYHAIKDGMDMGIVNAGSLPVYDDIDKENLIWNRDADATEKLLAYAQNIVKG----GKKVVQTDEWRVEER
LEYALVKGIEKYVVEDVEECQAQVKRPIHIIEGPLMNGMKMVGDLFGAGKMFLPQVIKSARVMKKAVGHLIPFMEKERLSPYQGTILLATVKGDVHDIGK
NIVGVVLGCNNFRVIDLGVMVPCDQILRAAVAHKADIIGLSGLITPSLDEMIYVAKEMERLGMRVPLLIGGATTSKRTAVKIAP-RYSLDASRSVVVCSQ
LL-
>tr|F6V492|F6V492_XENTR Uncharacterized protein OX=8364 OS=Xenopus tropicalis (Western clawed frog) (Silurana tropicalis). GN= PE=3 SV=1
--ELDSVLRE-RIMVLDGGMGTMIQQHTLQEEGNNDLLSITQSEIIYKIHKEYLTCGADIVETNTFSSTSIAQADGLLAYRLNKVSAEVARRAADDKRYV
AGAMGPTNKTLSDYRNVTFDELVDAYAEQARGLLDGGVDILLVETIFDTANAKAALFAIQKYEPRPIFISGTIVSGRTLSGQTGEAFVVSVSHAEPLCIG
LNCALGAIEMRPFIEAIGKCTTSYVICYPNAGLPNT-FGG---YDETPEVTAKHIKDFALDGVNIVGGCCGTTPAHIREIAEAVKNCKPRIPPTSVFDGY
MLLSGLEPFRIGPYTNFVNIGERCNVAGSRRFAKLIMSDNYEEALSVAKAQVEMGAQILDINVDDGMLDGPTAMARFCNYIASEAKVPLCIDSSNFNVIE
AGLKCCQGKCIVNSISLKEEDFLAKAKKIKQFGAAVVIMAFDEVGQATDTETKVSVCTRAYNLLEKLNFNPNDIIFDPNILTIGTGMEEAINFIEATKSI
KESLGARVSGGLSNLSFSFRIREAMHGVFLYHAIKAGMDMGIVNAGNLPVYDDIDKEDLIWNRDPDGTEKLLKYAQTKAKG----GKKVIQTDEWRVEER
LEYALIKGIEKFVIEDTEEARANKSRPLHIIEGPLMNGMKVVGELFGAGKMFLPQVIKSARVMKKSVGHLIPFMEKERENPYQGTIVLATVKGDVHDIGK
NIVGVVLGCNNFRVIDLGVMTPCDKILRAAIENKADIIGLSGLITPSLDEMIFVAKEMERLGIRTPLLIGGATTSRTTAVKIAP-RYNLDASKSVVVCSQ
LL-
>tr|G7MFM9|G7MFM9_MACMU Methionine synthase OX=9544 OS=Macaca mulatta (Rhesus macaque). GN= PE=2 SV=1
--EIDAILQK-RIMVLDGGMGTMIQRQKLNEEGNNDILSITQPDVIYQIHKEYLLAGADIIETNTFSSTSIAQADGLLAYRMNKCSAGVARKAAEEKRFV
AGALGPTNKTLSDYRNIKFDELVEAYQEQAKGLLDGGVDILLIETIFDTANAKAAVFALQNYAPRPIFISGTIVSGRTLSGQTGEAFVISLSHAEPLCIG
LNCALGAAEMRPFIEMIGKCTTAYVLCYPNAGLPNT-FGD---YDETPSTMAKHLKDFAMDGVNIVGGCCGSTPDHIREIAEAVKNCKPRVPLATVFEGH
MLLSGLEPFRIGQYTNFVNIGERCNVAGSRKFAKLIMAGNYEEALGVARVQVEMGAQVLDINMDDGMLDGPSAMTRFCNLIASEAKVPLCIDSSNFAVIE
AGLKCCQGKCIVNSISLKEDDFLEKARKIKKFGAAMVVMAFDEEGQATETDTKIRVCTRAYHLLKKLGFNPNDIIFDPNILTIGTGMEEAINFIHATKVI
KETLGARISGGLSNLSFSFRIREAMHGVFLYHAIKSGMDMGIVNAGNLPVYDDIHKEDLIWNKDPEATEKLLRYAQTQGTG----GKKVIQTDEWRVEER
LEYALVKGIEKHIIEDTEEARLNQPRPLNIIEGPLMNGMKIVGDLFGAGKMFLPQVIKSARVMKKAVGHLIPFMEKEREDPYQGTIVLATVKGDVHDIGK
NIVGVVLGCNNFRVIDLGVMTPCDKILKAALDHKADIIGLSGLITPSLDEMIFVAKEMERLAIKIPLLIGGATTSRTTAVKIAP-RYSLDASKSVVVCSQ
LL-
>tr|G3VJM1|G3VJM1_SARHA Uncharacterized protein OX=9305 OS=Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius). GN= PE=3 SV=1
--DIEAILKE-KIMVLDGGMGTMIQRYTLSEEGNNDLLSITQPDIICKIHKEYLMAGADIIETNTFSSTWVAQADGLLAYRLNKCSAEVARKAADDKRFV
AGSMGPTNKTLSDYRNITFDELVEAYQEQARGLLDGGVDILLVETIFDTANAKAALFALQKYDRRPIFVSGTIVSGRTLSGQTGEAFVISVSHAEPLCLG
LNCALGALEMRPFIETIGKCTTAYVLCYPNAGLPNT-FGE---YDETPEMTAMHIKNFALDGVNVVGGCCGTTPDHIREIAEAVKNCKPRVPPASIFDGY
MLLSGLEPFRIGPYTNFVNIGERCNVAGSKKFAKLIMAGNYEEALSVAKTQVEMGAQILDINMDDGMLDGPSAMTRFCNFIASEAKVPLCIDSSNFAVIE
AGLKCCQGKCIVNSISLKEDDFLAKAKKIKMYGAAVVVMAFDEVGQATETSNKIEICTRAYHLLKKVRFNPNDIIFDPNILTIGTGMEEAVNFINATKTI
KETLGAKISGGLSNLSFSFRIREAMHGVFLYHAIKFGMDMGIVNAGNLPVYDDIHKEDLIWNKDPDATEKLLRYAQTQAKG----GKKTIQTDEWRIEER
LEYALVKGIEKYIVEDTEEARMNKPRPLNIIEGPLMNGMKVVGDLFGAGKMFLPQVIKSARVMKKAVGYLIPFMEKERADPYQGTIVLATVKGDVHDIGK
NIVGVVLGCNNFRVIDLGVMTPCDKILRAAIDNKADIIGLSGLITPSLDEMIFVAKEMERLDIKIPLLIGGATTSRTTAVKIAP-RYSLDASKSVVVCSQ
LL-
>tr|Q8JIY6|Q8JIY6_DANRE Methionine synthase OX=7955 OS=Danio rerio (Zebrafish) (Brachydanio rerio). GN= PE=2 SV=1
--ELTELLQQ-RILVLDGGMGTMIQQRHLEEEGNNDILSITQPDVIYSIHKEYLEAGADIIETNTFSSTSIAQADGMLAYRLNKASAEVARRAADDKRFV
AGALGPTNKTLSDYRNITFDELVEAYAEQVKGLLDGGADVLLVETIFDTANAKAALFAIDRYEARPVLISGTIVSGRTLSGQTGEAFVISVSHAQPLCIG
LNCALGASEMRPFIEAIGKSTSAFVICYPNAGLPNT-FGG---YDETPDVTAAHLKEFAVDGVNIVGGCCGTTPDHIRAIAESVRHVKPRVPPTDVYSDY
MLLSGLEPFRIGPYTNFVNIGERCNVAGSRKFAKLIMAGNYEEALSIAKAQVEMGAQVLDINMDEGMLDGAAAMSRFCNLIASECKVPLCIDSSNFSVIE
AGLKCCQGKCIVNSISLKEQDFLRRARQVRRYGAAVVVMAFDEDGQATETDQKVQICSRAYHLLDQAGFNPNDIIFDPNILTIGTGMEEAINFIRATRII
KESLGARVSGGLSNLSFSFRIREAMHGAFLYHAIKDGMDMGIVNAGNLPVYDDIDKENIIWNRDPDATEKLLLYAQNNAKG----GKKVVQTDEWRVEER
LEYALVKGIEKYVVEDTEEARAQTPRPLHVIEGPLMNGMKTVGDLFGAGKMFLPQVIKSARVMKKAVGHLIPFMEKEREDPYQGTVLLATVKGDVHDIGK
NIVGVVLGCNNFRVIDLGVMIPCDRILREAIHNKADIIGLSGLITPSLDEMIHVAKEMERLGLKIPLLIGGATTSKTTAVKIAP-RYSLDASRSVVVCSQ
LL-
>tr|F1NLY0|F1NLY0_CHICK Uncharacterized protein OX=9031 OS=Gallus gallus (Chicken). GN= PE=2 SV=1
--EIESVLRE-RIMILDGGMGTMIQQHALSEEGNNDLLSITQPDIICDIHKEYLLAGADIIETNTFSSTRVAQADGLLAYRLNRISAEVARKAADDKRYV
AGSIGPTNRTLSDYRNITFDELVEAYTEQAKGLLDGGVDVMLVETIFDTANAKAALFALHKYAPRPIFVSGTIVSGRTLSGQTGEAFVISVSHSKPLCIG
LNCALGAVEMRPFIETIGKCTTAYVICYPNAGLPNT-FGG---YDETPEVTAKHIKNFALDGVNIVGGCCGTTPAHIRKIAEAVKLCKPRVPP-PLCQGY
MLLSGLEPFRIGPYTNFVNIGERCNVAGSRKFAKLIMAGNYEEALTVAKSQVEMGAQILDINMDDGMLDGPSAMTRFCNLISSEAKVPLCIDSSNFSVIE
AGLKCCQGKCIVNSISLKEEDFLEKARKIKLYGAAVVVMAFDEVGQATETETKIAICSRAYHLLEKVHFNPNDIIFDPNILTIGTGMEEAINFINATKTI
KETLGVRISGGLSNLSFSFRIREAMHGVFLYHAIRYGMDMGIVNAGNLPVYDDIHKENLIWNKDPDATEKLLRYAQNHAQG----GKKVMQTDEWRVEER
LEYALVKGIEKYVTADTEEARLNQPRPLNIIEGPLMNGMKIVGDLFGAGKMFLPQVIKSARVMKKAVGHLIPYMEKEREDPYNGTIVLATVKGDVHDIGK
NIVGVVLGCNNFRVIDLGVMTPCDKILRAAVENKADIIGLSGLITPSLDEMIFVAKEMERLAIKIPLLIGGATTSKTTAVKIAP-RYSLDASKSVVVCSQ
LL-
>tr|H2Z6R3|H2Z6R3_CIOSA Uncharacterized protein OX=51511 OS=Ciona savignyi (Pacific transparent sea squirt). GN= PE=3 SV=1
--EIEATLKQ-RIMVFDGGMGTMIQNLRLEEQGNNDLLSITKPDSIYEIHKAYLEAGADFIETNTFSGTSIAQADALFVYQLNFESARIAKKAAVDKRYV
AGSIGPTNKTLSEYRNITFDELVVAYSEQTRGLLDGGSDVLLVETIFDTANAKAALFAIQEYSPLPIFVSGTIVSGRTLSGQTGEAFVISVSHAKPMCLG
LNCALGAVEMRPFIEVIGNFTDAYVICYPNAGLPNT-FGG---YDETPATTAKYLAEFAASGVNIVGGCCGTTPEHIKAIADAVRPHKPRTPPNNPHKGC
LLLSGLEPAVISSITNFVNIGERCNVAGSRRFARLVQNGKYEAALDVARSQVEMGAQILDINMDEGMLDGKSVMPKFINLIGSESKVPLCVDSSNFDIVV
AGLKCTQGKCIVNSISLKEEDFINKAKLIKRFGAAVVVMAFDEDGQATSSEDKVRICTRSFRVLDQIGFEPNDIIFDPNILTIGTGMEEAINFIAATRII
KKNLGCRISGGLSNLSFSFRIREAMHSVFLYHAISAGMDMGIVNAGNLPVYDDIPKEDLIWNKNAEATETLLKYAQEHSGG----GNKAVESEEWRVEDR
LQHSLVKGIDKYVIEDTKECQENTPRALNVIERPLMKGMSIVGDLFGAGKMFLPQVIKSARVMKKAVGYLIPIMEEEKRNRFAGTVVIATVKGDVHDIGK
NIVAVVLGCNNYRVIDLGVMTPCEKILQTAVENNADIIGLSGLITPSLSEMIHVAKEMERLEMKIPLLIGGATTSRTTAVKISP-RYSLDASKSVVVISS
LL-
>tr|G1KBM2|G1KBM2_ANOCA Uncharacterized protein OX=28377 OS=Anolis carolinensis (Green anole) (American chameleon). GN= PE=3 SV=1
--EIESILRQ-RIMVLDGGMGTMIQQHTLTEEGNNDLLSVTQPDIIYKIHKEYLMFGADIIETNTFSSTRIAQADGLMAYRLNKMSAQVARRAADDKKYV
AGAMGPTNKTLSDYRNVTFDELVEAYTEQAKGLLDGGVDIMLVETIFDTANAKAALFALQNYEPRPLFVSGTIVSGRTLSGQTGEAFVISTSHSEPLCIG
LNCALGALEMRPFIETIGKCTTAYIICYPNAGLPNT-FGG---YDETPEVTAKHLKTFALDGVNIVGGCCGTTPAHIREIAEAVKGCKPRIPNSAFSEGY
MLLSGLEPFRIGQYTNFVNIGERCNVAGSRRFAKLIMANKYEEALSVAKAQVEMGAQILDINMDDGMLDGPSAMARFCNYIASEAKVPLCIDSSNFTVIE
AGLKCCQGKCIVNSISLKEEDFFAKARKIRKYGAAVVVMAFDEVGQATETKEKISICTRAYRLLNKVGFNPNDIIFDPNILTIGTGMEEAINFINATKTI
KETLGVKISGGLSNLSFSFRIREAMHGVFLYHAIKCGMDMGIVNAGNLPVYDDIHKEDLIWSKDSDATEKLLHYAQTHAQG----GKKVVQTDEWRVEER
LEYALVKGIEKYVVEDTEEARLNKSRPLHIIEGPLMNGMKTVGDLFGAGKMFLPQVIKSARVMKKAVGHLIPFMEQEREDPYHGTIVLATVKGDVHDIGK
NIVGVVLGCNNFRVIDLGVMTPCDKILRSALENKADIIGLSGLITPSLDEMIFVAKEMERLEIKIPLLIGGATTSKTTAVKIAP-RYSLDASKSVVVCSQ
LL-
>tr|E9G6S3|E9G6S3_DAPPU Putative uncharacterized protein OX=6669 OS=Daphnia pulex (Water flea). GN=DAPPUDRAFT_314321 PE=3 SV=1
--RLEEELGR-RILIIDGAMGTMIQKHRLEEEGNNDLLSITRPEIIYDIHTAYLEAGSDIIETNTFSGTWIAQADGLWAYRLNFESAKLAARAVADQCWV
AGALGPTNRTLSDFRNITFDELVDAYTTQARALLDGGADILLVETIFDTANSKAALFAIENYSRIPVMVSGTIVSGRTLSGQTGEAFVISVSHSNPLCIG
LNCALGAREMRPFIETIGRSTSAYVICYPNAGLPNT-FGG---YDETPDIMAESLRDFASDGVNIIGGCCGTTPDHIKAIKKIVEEYPPRKPSPNPYEGH
MLLSGLEPFRIGKDTNFVNIGERCNVAGSRKFLRLIKEGKYDEALQIAKEQVENGAQVLDINMDEGMLDGVAAMTRFLNLISSESKVPLCIDSSNFKVIE
AGLKCNQGKCIVNSISLKEEDFIHKATIVRKFGAAVVVMAFDELGQAADTDRKVEICVRSYKLLDKVGFNPNDIIFDPNILTIATGIEEGIDFIEACRRI
KKVCGCRVSGGVSNISFSFRIREAMHSVFLYHAIKAGLDMGIVNAGNLAVYDNIDSEAILWNKDAHGTEKLLEFAQTAVK-----GEKTVEVDDSRVEER
IENALVKGIDKYIVEDTEEARLDTPRPLNIIEGPLMKGMSVVGDLFGAGKMFLPQVIKSARVMKKAVGHLVPFMEKEREDRFAGTVVLATVKGDVHDIGK
NIVAVVLGCNNFRVIDMGVMVPCDKILERAIQEKADIVGLSGLITPSLDEMIHVAKEMQRIKLKVPLLIGGATTSKATAVKIAP-AYELDASRSVVVSSA
LL-
>tr|F1KS55|F1KS55_ASCSU Methionine synthase OX=6253 OS=Ascaris suum (Pig roundworm) (Ascaris lumbricoides). GN= PE=2 SV=1
--TISRIARE-RILIIDGAMGTMLQREHLQEAGNNDILSLTRPDIVYKIHKLYLEAGADFIETNTFSGTAVAQADQCLVHDINYRSAQIARKAADERRFV
CGAIGPTNKTLSEFRNITFQELVKAYDEQARSLIEGGVDVLLVETVFDSANAKAALFAIRTGI-EPVFLSGTIVSGRTLSGQTGEAFLISTRQGRPVAVG
LNCALGAKEMRPFIETIAMNTTALVLCYPNAGLPNA-LGG---YDERPEDMAAALLSYASDGVNIVGGCCGTTPDHIRAIAVAVKGVVPRKPPTSVNSGY
MMLAGLEPFVIGAHTNFVNIGERCNVAGSRRFCNLIKKNKYEDAIGVARKQVENGAQILDINVDDGLLDGPSTMTKFLRLIASEAKVPICVDSSNFEVLI
AGLESCQGKCIVNSISLKEEVFLQKARLVKRYGAALVVMAFDEEGQATDIERKYKICERSYRLLEEAAFDPCDIIFDPNILTIATGMEEGINFIEGTRLI
KENLGCFVSGGVSNFSFSFRVREAMHSVFLYHAIKAGMDMGIVNAGALPLYTDIRPEDLLWNKDSNATEKMLALAHELVSG----DKKA-ECDSWRVEKR
LEYALVKGIDSHIVEDTEEARQNTPRPLNVIEQPLMAGMAVVGELFGSGKMFLPQVIKSARVMKKAVAHLIPFMDKERESPYQGTFVIATVKGDVHDIGK
NIVAVVLGCNNFRVIDLGVMTPCEKIIKTAIDEKADFIGCSGLITPSLDEMVHVAREMQRAGLSIPLLIGGATTSKTTAVKIAP-RYSLDASKTVVACSS
LC-
>tr|H3B9U9|H3B9U9_LATCH Uncharacterized protein OX=7897 OS=Latimeria chalumnae (West Indian ocean coelacanth). GN= PE=3 SV=1
--EIESVLRE-RIMVLDGGMGTMIQQRRLEEEGNNDLLSVTCPGIVYSIHKDYLMAGADIVETNTFSGTRVAQADGLLAYRLNKASAELAKKAATEKRFV
AGAIGPTNRTLSDYRNITFDELVEAYEEQTRGLLDGGADVLLVETIFDTANAKAAVFAIDKYEPRPIFISGTIVSGRTLSGQTGEAFVISMSHAQPLCIG
LNCALGAAEMRPFIEAIGNCTTSYVICYPNAGLPNT-FGD---YDETPERTAKHLKEFALDGVNIVGGCCGTTPAHIREVAKAVRNCKPRVPPSSVFEGY
MLLSGLEPFRIGPYTNFVNIGERCNVAGSRRFAKLIKAGNYEEALSIAKSQVELGAQVLDINMDEGMLDGKSAMTRFCNLIASEAKMPLCIDSSNFSVIE
AGLKCCQGKCIVNSISLKEQEFLERTQTIKRFGAAVVVMAFDEEGQATETERKVQVCARAYSLLEKVGFNPHDIIFDPNILTIGTGMEEAVNFIRATTNI
KETLGARVSGGLSNLSFSFRIREAMHGVFLYHAIKSGMDMGIVNAGNLPVYDDIDKENLIWNKDPEATEKLLHYSQTCAKG----GKRVIQTDDWRVEER
LEYALVKGIEKYVVEDTEEARANHPRPLNVIEKPLMNGMKMVGDLFGAGKMFLPQVIKSARVMKKAVSYLIPFMEKEREDPYQGTIVLATVKGDVHDIGK
NIVGVVLGCNNFRVIDLGVMTPCDNILRAAVESKADVIGLSGLITPSLDEMIYVAKEMERLGMKTPLLIGGATTSKTTAVKIAP-RYSLDASKSVVVCSQ
LL-
>tr|I1FAB7|I1FAB7_AMPQE Uncharacterized protein OX=400682 OS=Amphimedon queenslandica (Sponge). GN= PE=3 SV=1
--TLANEMRK-RIMVLDGAMGTMIQGHNLTEEGDNDLLCLTQPDIIYNIHKQYFEAGADFSETNTFNGTSISQSDGLLVYRINKSAAEIARRAAADPKYV
VGALGPTNRTLSDFRNITFDELVDSYSEQAQGLLDGGVDVLMVETIFDTANSKAALYAIETYKPIPVFVSGTIVSGRTLSGQTSEAFLFSVTHSKPLCIG
LNCALGATEMRPFIQTVSRSTEAFVLCYPNAGLPNA-LGG---YDETPEVMASHLKSFAVDGVNIVGGCCGTTPLFIKAIAEAVKGLKPREPPTNLYHDA
LILSGLEGVKINSTTNFVNIGERCNVAGSRRFARLIIAGKFEEALAVAKQQVEMGAQVLDLNMDEGMLDGVKAMARFCNYISTEAKLPLCIDSSNFSVVL
AGLKCSQGKCIVNSISLKEEDFIEKAKIIKKFGGAAVVMAFDEVGQATTTENKVSICTRSYNILDVVGFNPNDIIFDPNILTIATGMEEGISFIEATRLI
KQTLGARISGGLSNLSFSFRIREAMHSVFLYHAIQAGMDMGIVNAGNLPLYDDIKKEDLLWNRDPNTTEKLLEYAQSLGEG----AKKQVATDEWRVEER
LEYSLVKGIDKFVVSDTEEARSNFPRPLHIIEGPLMSGMSIVGDLFGSGKMFLPQVIKSARVMKKAVGYLIPFMEEEKEDRFSGTVVIATVKGDVHDIGK
NIVGVVLGCNNFRVIDLGVMTPCEKIIETARKNKADIIGLSGLITPSLDEMIYVAKEMEREGLKIPLLIGGATTTKTTAVKIAP-CYSVDASKSVVVVST
LL-
>tr|A7SKT1|A7SKT1_NEMVE Predicted protein OX=45351 OS=Nematostella vectensis (Starlet sea anemone). GN=v1g245922 PE=3 SV=1
-------------MIFDGGMGTMIQKLHLEEAGNNDLLSITKPDAILDIHKGYLEAGADFVETNTFSGTKIAQADGLAAYRLNRASAEVAKRAAYEEKFV
AGAMGPTNRTLSGFRNVTFDELVDAYTEQARGLLDGGVDVLLVETIFDTANAKAALFAIDQYSPVPVFVSGTIVSGRTLSGQTTESFVISVSHSSPMCIG
LNCALGAVEMRPFIEAVGMNTEAYTICYPNAGLPNT-FGD---YDETPETMAKHLK----------ARCCGTTPEHIRAIAEAVRPYKPRMRPEDLHSDA
LSLCGLESMRINPSVLFVNIGERCNVAGSRMFCKLIKNGKFQ---------------------------------------------PLCIDSSNFDVIE
AGLKCAQGKCIVNSISLKNEDFLDKARIIKRYGAAVVVMAFDEQGQAADCERKVEICTRSYNLLKEAHFEPNDIIFDPNILTVATGMEEGKYFIQATRII
KETLGARVSGGLSNFSFSFRIREAMHSVFLYHAIKAGLDMAIVNAGALPVYDDIEKEDLLWNRDPEATEKLLQLAQSMGPG----AKKVTITDEWRVEER
LEFALVKGIDKYVIEDTEEARVNTPRPLNVIEGPLMKGMGVVGDLFGAGKMFLPQVIKSARVMKKAVGHLIPFMEEERQSKYNGTIVLATVKGDVHDIGK
NIVGVVLGCNNYRVIDLGVMTACEKILQTAIEEEADIIGLSGLITPSLDEMIHVAKEMERQGLKIPLLIGGATTSRTTAVKIAP-RYSLDASKSVVVCSA
LM-
>tr|J9GIW3|J9GIW3_9ZZZZ B12-dependent methionine synthase OX=749906 OS=gut metagenome. GN=EVA_12400 PE=4 SV=1
---LENLVRQ-RILVLDGAMGTMIQLYNLTPGQNNDVLCLTCPEVIRDIHRKYLEAGADIIETNTFNAQRISQADHHLVRDINLSAARLARALADEPRLV
AGSVGPTSKTCSPYRSLTFDTLTDAYIEQMVALLQGGVDVLLIETIFDTLNAKAALFAAEEAHRVPLMLSVTVSAGRTLSGQTLEAFLASVQHANLFSVG
LNCSFGARQLKPFLAHLAARAPYYISAYPNAGLPNS--LG--QYDQTPEDMEREIADYLHEGVNIIGGCCGTTDAYIARFVSLVQDAVPHVPVP--RPVN
LWLSGLELMEVKPENNFVNVGERCNVAGSRKFLRLIKEKNYEEALGIARRQVEDGAQIIDINMDDGLLDAVQEMTIFLNLIASIARVPVMIDSSKWEVIE
AGLKCLQGKGIVNSLSLKEGVFLSHARAVRQYGAAVVVMAFDEKGQADTYERRIEVCQRAYTLLEKVGFLPQDIIFDPNVLAVATGMEEAVDFIRATAWI
RTHLGSHVSGGVSNLSFSFRIREAMHAVFLYHAIRAGMDMGIVNPATSVLYTDIPAEDVVLNRRPAAEHLIEIAQQLKAT------IVHQTRE-GTVDER
LKYALVKGVGDYLERDLAEALQQYPKAVDIIEGPLMEGMNLVGNLFGAGKMFLPQVVKTARTMKKAVSILQPVIEQQPVGAKAGKVLLATVKGDVHDIGK
NIVSVVMACNGYEIIDLGVMVPAETIVQRAIEDQVDMIGLSGLITPSLEEMVHVAKELEHRGLNIPLLIGGATTSQLTALKIAPVYHLKDASQNVSVAAR
LM-
>tr|J9FM81|J9FM81_9ZZZZ B12-dependent methionine synthase OX=749906 OS=gut metagenome. GN=EVA_21195 PE=4 SV=1
---IAQLVPE-RILILDGAMGTMIQQYDLTPGQNNDLLCLTRPDIIQDIHRKYLEAGADIIETNTFSSTTVSMADHEYVREINLAAVKLARELADEPRFV
AGSVGPTNKTCSPFRALSYDELTAAYQQQMEALLEGGVDALLIETIFDTLNAKAAIYAAQQAVKVPIMLSVTVSGGRTLSGQTLDAFLASVQHADIFSVG
LNCSFGARQLKPFLAQLAARAPYFISAYPNAGLPNS--LG--KYDQTPADMAKEVADYIKEGVNIIGGCCGTTDAYIAEYPALTAGAKPHVPAP--APTH
LWLSGLELLEVKPEINFVNVGERCNVAGSRKFLRLINEKKYEEALSIARKQVEDGALVLDVNMDDGLLDARTEMTTFLNLIMSIARVPIMIDSSKWEVIE
AGLKCLQGKSIVNSISLKEGLFLEHARKVKQYGAAVVVMAFDEKGQADTAARKIEVCERAYHLLDKVGFNPNDIIFDPNVLAVATGIEEAVDFIKATSWI
KQHLGAHISGGVSNLSFSFRIREAMHAVFLYHAIRKGMDMGIVNPSTSVIYTDIPAEDVVLNRRPAAERLIELAEQLKKAQQPQANVHHDARD-DSVEDR
LKYALKKGIGDYLEADLAEILPKYARAVDVIEGPLMDGMNEVGELFGAGKMFLPQVVKTARTMKKAVAILQPIIESEKNTTSAGKVLLATVKGDVHDIGK
NIVSVVMACNGYEIIDLGVMVPAETIIERAIEEKVDMIGLSGLITPSLEEMVHVASELEKRGLDFPLLIGGATTSKMTALKIAPVYHLKDASQNAGIAAR
LL-
>tr|J9C9T9|J9C9T9_9ZZZZ Methionine synthase (B12-dependent) OX=749906 OS=gut metagenome. GN=EVA_15245 PE=4 SV=1
---LRQLINE-RILILDGAMGTMIQQYPLTPGQNNDLLCLTRPDVIRDIHRKYLEAGADLIETNTFNAQRVSMADHDCCREINLKAARLARAEADAPRFV
AGSVGPTNQTCSPLRTLTYDSLVAAYREQMEALLEGGVDALLIETVFDSLNAKAALFAAQEAREVPLMLSVTVSAGRTLSGQTLEAFLASVQHAPIFSIG
LNCSFGARQLKPFLKVLADRAPYYISAYPNAGLPNS--LG--QYDQTPEAMAAEVQEYLDEGVNIVGGCCGTTEAYIAQYVPRVAKARPHVPVA--PSDR
LWLSGLELLEQTPEVPFINVGERCNVAGSRKFLRLINEKNYDEALSIARKQVEDGALVIDVNMDDGLLDAKEEMVTFLNRLMSIARVPVMIDSSKWEVIE
AGLKCLQGKSIVNSISLKEGVFLQRARSIQRLGAAVVVMAFDERGQADTYERKIEVCERAYRLLEQAGFRPTDIIFDPNVLSVATGIEEAVDFIRATAWI
RQHLGAHVSGGVSNLSFSFRIREAMHAVFLYHAIRAGMDMAIVNPATSVLYTDLPAEDVVLNRRPAAERLIETATALKETAAVTDTVKHDVRD-ESVDKR
LQHALVKGIGDYLEADLHEALQQYPKAVDIIEGPLMEGMNQVGELFGAGKMFLPQVVKTARTMKKAVAILQPSIEADKGTRSAGKVLMATVKGDVHDIGK
NIVAVVMACNNYEVIDLGVMVPAETIVQRAIEEQVDMIGLSGLITPSLEEMVHVAQELKRAGLDIPIMIGGATTSKLTALKIAPVYHLKDASQNALVAAR
LM-
>tr|D8TLD6|D8TLD6_VOLCA Vitamin B12 dependent methionine synthase OX=3067 OS=Volvox carteri (Green alga). GN= PE=4 SV=1
---LDKLLRE-RIIFIDGAMGTQVQKYKLEEGENNDVLVITRPDVIGQIHTAYLEAGADIIETNTFNGTCISQADELEVALINRTAAQLAKKCVKDPRFV
AGAIGPTNKTLSAFRGITYDEVVDAYYKQIEALYEGGIDMFLVETIFDTLNAKAAVFALEQFVRVPVFISGTIVSGRTLSGQTNEAFWNSINHAKPMAVG
LNCALGASDMLKYIANLSACADCYVLCYPNAGLPNA-MGG---YDQKGGEMAEEIRPFCEAGVNAIGGCCGTGPEHIAAIKAMASAYPPRKPPAT-EPLM
RI-SGLEPLNYNPDRTFLNIGERCNVAGSILFKKAIINNDYEKAVAIALQQVQQGADVLDINMDDGLIDGVAAMTRFVNLLVSISRVPFMIDSSKFHIVE
AGLKCSQGKCIVNSISLKEEAFCKQAEIVKRHGAAVVVMAFDEQGQAAGYADKVRICCRAYKLLEQVGFNPQDIIFDPNILTVGTGNNYAVDFIRATREI
K-RLGAKISGGVSNIAFSFRGRRAFHSAFLQHACAAGMDMGIVNAAQKELLEFV--EDVLLNKCENATERMLEFAALKPTKGTQGAAGAGAKKSWRVEKR
IEYALVKGIDEFAVVDTEEARTCGTKPLHVIEGPLMDGMNVVGDLFGAGKMFLPQVIKSARVMKKAVGHLVPFIEEEKEDSNAGVFVLATVKGDVHDIGK
NIVGVVLGCNNFKVIDLGVMTPWDVILDAAEKHKANIIGLSGLITPSLDEMVTVAKKMEERGLKTPLLIGGATTSKMHAVKIA-PVYSLDASRSVPVCQA
F--
>tr|H3CJI2|H3CJI2_TETNG Uncharacterized protein OX=99883 OS=nigroviridis). GN= PE=3 SV=1
--ELRGILER-RIMILDGGMGTMIQQHKLEEGGNNDLLSLTCPDIVYKIHKDYLLAGADIIETNTFSGTSVAQADGLMAYRLNKASAELARKAADDKRYV
AGALGPTNKTLSHFRNITFDALVEAYTEQVKGLLDGGVDILLVETIFDTANAKAALFAIKSYSRKPIFISGTVVSGRTLSGQTVEAFVVSVSHAKPLCIG
LNCALGATEMRPFIEAIGKCTTAFVICYPNAGNPHL-FNQYLSDTVRPTHISFNAKEFSVDGVNIVGGCCGTTPEHIRALCEAVKMCQPRVAPAEMYKDY
MMLSGLEPFKVGPYTNFVNIGERCNVAGSRKFAKLITSGLYEV--RLASRNHFSRPSMLDSD----LINGCLFFFRCSEKTSEIRKVPLCIDSSNFSVIE
AGLKCCQGKCIVNSISLKEGESDDKAASVKRYGAAVVVMAFDEHGQATDTDRKVEICTRAYQLLTKVGFKPNDIIFDPNILTIGTGIEYAINFIKATKLI
KETLGARVSGGLSNLSFSFRIREAMHGVFLYHAIKSSVQINLM------TMQRIKMYR------PEQKKILEKCKNWQKGIVVSIIKEKASTGGTATPLR
LLKVYSQGVDKYVVEDVKKQVDRYTRPIHIIEGPLMSGMKIVGDLFGPGKMFLPKVIKSARVMKKAVGYLIPFMEKEREDPYMGTIVLATVKGDVHDIGK
NIVGVVLSCNNFRVIDLGVMVPCDKILKEAIIHNADIIGLSGLITPSLDEMIHVAKEMERLRMTIPLLIGGATTSKTHAVKIAP-RYALDASRSVVVCSQ
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>tr|A6DGP4|A6DGP4_9BACT 5-methyltetrahydrofolate--homocysteine methyltransferase OX=313628 OS=Lentisphaera araneosa HTCC2155. GN=LNTAR_23264 PE=3 SV=1
-MKFLDALKE-QILVLDGAMGSMVQLLKLPDAMLSDLLVFSRPDQVRNIHLEYLKAGANILETNTFGASPLRLQEDFSLSYFNIRGIELAQDAIEKPLFV
AGSIGPSNWVISNLNKTDFATIKQNFYLQVKAMMQANVDVLLFETQQDMLELKASIAGAHQLGKVPIMAQVTVDNKMQIFNTDMEAAYAAVGGIGIDVFG
INCTLGPELMQKVIPALAQMSELPISVVPNAGQPIS-VNGETVYPLAPEKMGEYMRDYEENGINIVGGCCGTTPAHIAEITKHLGGKKPKVREV--KRRN
LISGPQNAFELDASEGLIQIGERLNVRGSKKVRDAVEVED--NIDNDALEQRDLGIDILDVCMDSNIVNTEKVLPKVIYDMTMDFGGAFCIDSFAVDALE
VAIDVYPGRPIINSIALEESKIDAIVPLTKHHNPVYIALVTDGDGPALTADKKLELAEKIVAESAKHGVTPDQLMIDINAFPIGAESIEALESLNSLKPI
KAIHEIMTSIGVGNLTNGLAKKPYLTSVFLDEGYKRGLDAAIVNPNHFIPVESIEPYDYELGKKVIFDRDMDAFEELETIAESRRGIVKEKKC-SYDDMP
VEEAIKDGYKEKSEGSMKDIVDVH-QPLDFINDYLMEAMRELGDGFGRGEVSLPHLLKSADVMKHCMNFLEAYMKNSGERTFKGTVIIGTVYQDVHSIGK
DLAKTLLENYGYRVIDLGVQVPLEKFIDTAIAENADAIGMSALLVQTSNHMITVQQMCQEKGVDFPLLIGGAPVNSDFAAMNGKVFYCQSGMDGVNIMNT
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>tr|K8F2M0|K8F2M0_9CHLO Methionine synthase OX=41875 OS=Bathycoccus prasinos. GN=Bathy07g01400 PE=4 SV=1
------IMSE-RVMIIDGAMGTSVQAYKLKEEDNNDILVLTRPDVIKEIHSAYLAAGADIIETNTFNATMISQADALDVWDINVAAAKLAKECCVDPRFA
AGAIGPTNRTLSAFRACTFDEIVEAYYEQTEALIEGGVDVLLVETIFDTLNAKAALFAVNKYKKIPVFVSGTIVSGRTLSGQTNEAFWNSVSHAKPIAIG
LNCALGAQDMVPYIDNLSKCADCWVFAYPNAGLPNA-MGG---YDQKGPEMAKDCETFFEKNLNAIGGCCGTTAEHIASLAELGARYKPRQRHEVPE-QM
RLS---GLLPFNPNKSFINLGERCNVAGSSIFKKAIVDGNFEKALAIALKQVENGAHVIDINMDDGLIDGKSAMTKFVNLLVSASKVPFMIDSSKFDVVE
AGLKCSQGKCIMNSISLKQDQFLKDAALVKAHGAAVVVMAFDEEGQAATEAEKVRICCRAFKLLEEVGFNPQDIIFDPNILTIGTGMEEAVDFINATREI
K-RLGCKISGGVSNLAFSFPVRRGFHSAFLYHACKAGMDMGIVNAAQVELLEY--IEDVLLNRCSNATERMLQFAATPKRRKGQAAGGAAKKKDWRNGKR
LEYALVHGIDEFCIADTEECRTSGSSCLEIIEGPLMDGMNVVGDLFGAGKMFLPQVIKSARVMKKSVGHLLPFMQAAKSSSSAGTFLIATVKGDVHDIGK
NIVAVVLGCNNFKVIDIGVMCPCQTILDAVKENNADILGLSGLITPSLDEMVTVGKEMEKAGLKIPLLIGGATTSKMHTAVKMAPVYSLDASRAVPVAQT
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