>seq_1
MTELPAPLSYFQNAQMSEDNHLSNTVRSQNDNRERQEHNDRRSLGHPEPLSNGRPQGNSRQVVEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATI
KSVSFYTRKDGQLIYTPFTEDTETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSFIYLGEVFKTYNVAVDYITVAL
LIWNFGVVGMISIHWKGPLRLQQAYLIMISALMALVFIKYLPEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAE
GDPEAQRRVSKNSKYNAESTERESQDTVAENDDGGFSEEWEAQRDSHLGPHRSTPESRAAVQELSSSILAGEDPEERGVKLGLGDFIFYSVLVGKASATA
SGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFATDYLVQPFMDQLAFHQFYI
>tr|Q9GU38|Q9GU38_HELLU Presenilin OX=31229 OS=Helix lucorum (Snail). GN= PE=2 SV=1
-MSTEDDVNAVPEATVVDPRSQGDASSRSAGNNSRHQ-VTSQARSERRAPPNTEPSGG------NQDEDDDEETLLYGAKHVIMLFIPVTLCMVVVVATI
SSITYYTSGGVYLIYTPFHDVTEDTGTKLWQSMANAVILLCVIVVMTVVLLLLYKYKCYRVINGWLVLSSIMLLFFFSFMYLEQILRAYNAPMDYVTVAI
IMWNFGVGGLFCIHWKGPLLLQQAYLIVVSALVALMFIKYTPDWTTWAVLGVMVIWDLVAVLCPKGPLRMLVETAQSRNEPIFRALIYSSTMMWPVTMAD
DGDQSKKKQKKKGLKTGA--QNSSVTTPLGKDTDDDDGGFTEHVANGDKPDRNAANSRSQNPALQRRPL-DSDDEERGVKLGLGDFIFYGVLVGKASSN-
-GDWNTTLACFVAILIGLCCTLLLLAIFRKALPALPISLTFGLVFNFATSSLVQPFMDSLASEQVYI
>tr|E2QDB2|E2QDB2_APLCA Presenilin 1-1 OX=6500 OS=Aplysia californica (California sea hare). GN= PE=2 SV=1
YSAADDEATTVPETSVVTPSTNSTTNQQPQSQRTRRG-EGSQNRSDGDGAAATRGGGASGGAVQQEEEDDGEETLLYGAKHVIMLFVPVTLCMVVVVATI
SSITYYTTKGTYFLYTPFHDKTEDTGTKLWQSMANALILLGAIIVMTIVLLLLYKYECYKIINGWLVMSSVMLLFFFSYIYLEQILRAYNVPMDYITVAI
IMWNFGVGGLFCIHWKGPLLLQQAYLISISALVALMFIKFLPDWTTWAVLGVMVVWDLVAVLCPKGPLRMLVETAQNRNEPIFPALIYSSTMVWTITMAD
GDPNKKKNQKKKQETTTA--EESANGAQASGGADEDDGGFQEHIQNGDSPQRAKPRPRAQRQNRQRNES-ETDEEDRGVKLGLGDFIFYGVLVGKASSN-
-GDWNTTLACFVAILIGLCFTLLLLAIFRKALPALPISLTFGLVFNFATSALVRPFMDSLASEQVYI
>tr|F1KXR4|F1KXR4_ASCSU Presenilin sel-12 OX=6253 OS=Ascaris suum (Pig roundworm) (Ascaris lumbricoides). GN= PE=2 SV=1
APSEPSGSSCSQPVRAVKCKKGSSTSKWRDGSS-RQK-EARHPHHSSDSSRPRHPTNG-----NGECSEDDEMELKYGAQHVIHLFVPVSLCMAFVIFTM
NTVGYYSRKDGQLIYTPFTKETDDTGERLMMSFGNAFVVLAVVVVMTIVLILLYKFRWYKLIHGWLIASSLMLLSLFTFMYLQEVFKSYNTPVDYIAIGF
VIWNYAAVGMICIHWTGPLRLQQGYLIMMSALMALTFIKYLPEWTVWTVLAVISIWDLIAVLCPKGPLRILVETAQERNEPIFPALIYSSGMLYAYTIVT
ADEQGDTATTSTTVAPADGSSPSSAELLLSNTDHSLPKNAVSVANDPISAGETASSARPRREVLDAERLQNPQQEERGIKLGLGDFIFYSVLVGKASSY-
-GDWNTTIACYVAILIGLCFTLVLLAVFRKALPALPISIFAGLIFYFCTRQIVTPFCTAISLRQIVF
>tr|A8PAF6|A8PAF6_BRUMA Presenilin family protein OX=6279 OS=Brugia malayi (Filarial nematode worm). GN=Bm1_20450 PE=4 SV=1
IHQTASGLNKTERIKSKTEQESRIQASPFNHSN-KEY-PSRHSHTGRDTARSETVENA-----THEADDEEESEFKYGAQHVIHLFVPVSICMVFVIFTM
NTVGYYTRKDGQLIYTPFTKETDNTGEKLIMSFGNAFIILGVVVTMTVLLIFLYKFRFYRVISAWLVLSSLILLSLFTFMYLQEVFKSYNVPVDYILICI
FIWNYGVMGMICIHWKGPLRMQQGYLIMMSALMALIFIKYLPEWTVWTVLAVISIWDLVAVLCPKGPLRILVETAQERNEPIFPALIYSSGLLYAYTLVT
GNTQSESGNPGSSTGSTNGSLPSTAELLPANDANGVENAGLNTEQSDIGKGRTAGGTQRVTTEVNPAGLQNERPDEKGIKLGLGDFIFYSVLVGKASSY-
-GDWNTTVACYVAILIGLCFTLILLAVFRKALPALPISIFCGLIFYFCTRGIITPFCTSLSLRHLIY
>tr|C1LIU9|C1LIU9_SCHJA Presenilin OX=6182 OS=Schistosoma japonicum (Blood fluke). GN= PE=2 SV=1
MSTRQSS---------------SQPVRRLNKTHGQPSHSDV----SNSASRNHLPVHNHESII----SINPDQMLYYGAKQIISLFIPVTVCMLFVVTVA
STVDFYGHTDQYLLYTPFHTPDADIGTQTWQTIANTLIFMSVVVVMTCILVLLFKYQCYKFIRGWIIMTTVFLLFLISFMFFAEVLRAMGVFVDYITVAF
TLWNFGVVGMIVIHWRGPLILQQAYLIFISAQIALMFLKYLPKWTCWLVLAALSIWDIVAVLCPNGPLRMLVEMAHERQQPLFPALLYSTTAVYLVKKVD
KVENSQPSVVSVNTHTADETQTTSGYSVPDNSQPTLDANMNHNNDSKQVPHETDPFISRRVRELQADLI-DRD--SKGVKLGLGDFVFYSLLIGRATLD-
-GDAVTVVTCYVAILVGMCITIIVLGITRRALPALPISIACGILFYFVSSATISPFLEATAIERVFF
>tr|I3IV36|I3IV36_ORENI Uncharacterized protein OX=8128 OS=Oreochromis niloticus (Nile tilapia) (Tilapia nilotica). GN= PE=4 SV=1
MANNAEDIENQQEANRSPDSTQKPQETGVPRARSRGGSAGAGGGNGTGPEQNGQPPAAAPRVVEEEEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATI
KSVSFYTQNDGQLIYTPFPEDTDTVGQRALNSILNATIMITVIIVMTLVLVMLYKYRCYKVIQGWLFLSSLLLLFFFSYIYLKEVFKTYNLAMDYITLAI
IIWNFGVVGMMCIHWKGPLRLQQAYLIMISALMALVFIKYLPEWTAWLILAVISVYDLLAVLCPKGPLRILVETAQERNEPIFPALIYSSTMVWLVNMAD
TDRPNRNSTEAASPQQEPEAVASPVPSSPSQDDGGFTQSWVSQQEHRLGPLQSTEETRREIQQMPSARPPVEEDEERGVKLGLGDFIFYSMLVGKASATA
SGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPISIFFGLVFYFATDNLVRPFMDKLALHQFYI
>tr|F6PH04|F6PH04_MONDO Uncharacterized protein OX=13616 OS=Monodelphis domestica (Gray short-tailed opossum). GN= PE=4 SV=1
MTELSAPLPYFQNAQMTEDSHMSNTVRNQNDGRERQEHSERRRHGNSEAETNGQPQGGTRQVVENDDEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATI
KSVSFYTRKDGQLIYTPFTEDTETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSFIYLGEVFKTYNVAMDYITLAL
MIWNFGMVGMICIHWKGPLRLQQAYLIMISALMALVFIKYLPEWTAWLILAVISIYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAE
GDPEAQRRVSKNSNYNAQTPSNQNSSNVTDSDDGGFSEEWEAQRDRNLGHHHSTPASRAAVQEIPAGVSTSEDPEERGVKLGLGDFIFYSVLVGKASATA
SGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFATDYLVQPFMDQLAFHQFYI
>tr|F6YF14|F6YF14_XENTR Uncharacterized protein OX=8364 OS=Xenopus tropicalis (Western clawed frog) (Silurana tropicalis). GN= PE=4 SV=1
MTKLSASLTQLQQIQETE-DFTDNRPANMNDQRNDNDTNERRSNEHSESQSNGQTQSSSQQVLEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATI
KSVSFYTRYDGQLIYTPFTEDTDSVGQRALNSILNTAIMISVIIVMTILLVVLYKYRCYKVIHGWLIISSLLLLFFFSYIYLGEVFKTYNVAMDYITLAL
MIWNFGVVGMICIHWKGPLLLQQAYLIMISALMALVFIKYLPEWTTWLILAVISVYDLIAVLSPKGPLRMLVETAQERNETLFPALIYSSTMIWLVKMAD
GDPGFKQSASKKT-YNAQPVAQPRSDSAASDDNGGFDTAWEEQRNEQIGQINSTPESRAAVQALPSNNPPSEDPEERGVKLGLGDFIFYSVLVGKASATA
SGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFATDYLVQPFMDQLAFHQFYI
>tr|G1KSC0|G1KSC0_ANOCA Uncharacterized protein OX=28377 OS=Anolis carolinensis (Green anole) (American chameleon). GN= PE=4 SV=1
MAELSAHLSQVQRGQLKEDNHLTNT--NDNIERRRQEGSSQRRTDNPDAASNGQPQNSTRQVVEQDDDDEEELTLKYGAKHVIMLFVPVTLCMVVVVATI
KSVSFYTRKDGQLIYTPFTEDTETVGQRALNSVLNAAIMISVIIVMTILLVVLYKYRCYKVIHGWLIVSSLFLLFFFSFIYLGEVFKTYNVAMDYITVAL
MIWNFGVVGMICIHWKGPLRLQQAYLIMISALMALVFIKYLPEWTAWLILAVISVYDLIAVLCPKGPLRMLVETAQERNETLFPALIYSSTMIWLVNMAE
EDPEAQKRAPKSSTYDKQVTANQNQNAGAETDDGGFSQEWEQQRDNRIGPLESTPETRAVVQAMPADSVGSEDPDERGVKLGLGDFIFYSVLVGKASATA
SGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFATDNLVQPFMDQLAYHQFYI
>tr|I6SI17|I6SI17_BOMMO Presenilin isoform B OX=7091 OS=Bombyx mori (Silk moth). GN= PE=2 SV=1
MSESGSDHTALMDGHIAEARPDRELAERIARKRKTKS-DNQRSYGSVEQIEGGPSGAS-----APVEPQIEELELKYGARHVIKLFVPVTLCMLVVVATI
SSINFYSVKDVYLAYTPFHEESPYASTKVWNALANSMILLCVIALMTVLLIVLYKKKCYKTIHGWLILSSLILLFLFSYLYIEEALIAYNIPMDYITLGF
VLWNFGVMGMIVIHWKGPLRLQQAYLIFIAALMALVFIKYLPEWTTWAVLAVISIWDLVAVLTPKGPLRILVETAQERNEPIFPALIYSSTVMYCMAAAS
PAPGAAG--------TVE--GEGRDGTEAGGGEAGFDAAWRERRDEGAAPLRVDAPPRYVTPHAPPHAP-DLD-EEKGVKLGLGDFIFYSVLVGKASSY-
-GDWNTTLACFVAILIGLCLTLLLLAILKKALPALPISITFGLIFYFATRSVVKPFADALAAEQVFI
>sp|Q4JIM4|PSN1_CHICK Presenilin-1 CTF subunit OX=9031 OS=Gallus gallus (Chicken). GN= PE=1 SV=1
MTELSAHLPQFQHGQMTEDNHLSNT--NDNSERRRHDNSERRRNDNPGSETNGQPQNNIQQVVDQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATI
KSVSFYTRKDGQLIYTPFTEETDTIGQRALNSILNAAIMISVIIVMTILLVVLYKYRCYKVIHGWLIISSLLLLFFFSFIYLGEVFKTYNVAMDYITVAL
IIWNFGVVGMICIHWKGPLRLQQAYLIMISALMALVFIKYLPEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAE
EDPEGQRKASKNSTYDKQAPANQSQNEDAEADDGGFSQEWQQQRDNRIGPIESTPESRAAVQALPSNSQTSEDPEERGVKLGLGDFIFYSVLVGKASATA
SGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFATDNLVQPFMDQLAFHQFYI
>tr|J3S0J3|J3S0J3_CROAD Presenilin-1-like OX=8729 OS=Crotalus adamanteus (Eastern diamondback rattlesnake). GN= PE=2 SV=1
MAELSAHFSQVPRGQLREDNQLTNT--NVNNERRQQESGDQRVN-NPIPASNGQPQPRPRQVVEQEEEEEEELTLKYGAKHVIMLFVPVTLCMVVVVATI
KSVSFYTRKDGQLIYTPFTEDTETVGQRALNSVLNAAIMISVIVVMTVLLVVLYKYRCYKVIHGWLIVSSLFLLFFFSFIYLGEVFKTYNVAMDYITVAL
MIWNFGVVGMICVHWKGPLRLQQAYLIMISALMALVFIKYLPEWTAWLILAVISVYDLIAVLSPKGPLRMLVETAQERNETLFPALIYSSTMIWLVNMAE
QDTEAQKGASKNATYSQQVTVNQNQNAGPEVDDGGFNPEWEQQRDNRIGPIQSTRETRAVVQALPTNSLASEDPEERGVKLGLGDFIFYSVLVGKASATA
SGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFATDNLVQPFMDELAYHQFYI
>tr|H2S0V7|H2S0V7_TAKRU Uncharacterized protein OX=31033 OS=Takifugu rubripes (Japanese pufferfish) (Fugu rubripes). GN= PE=4 SV=1
FTETPSELKNQEPSVVNHEPAVQPQEVSVTRSRSRGG----GGHGEGGPEQNGQPPATAAHVVETEEDEDEELTLKYGAKHVIMLFVPVTLCMVVVVATI
KSVTYYTQNDGQLIYTPFPEDTDTVAQRALNSILNATIMITVIIIMTLVLVVLYKYRCYKVIQGWLFLSSLLLLFFFSYIYLQEVFKTYNLAMDYFTVAI
IIWNFGVVGMMCIHWKGPLRLQQAYLIMISALMALVFIKYLPEWTAWLILAVISVYDLLAVLCPKGPLRILVETAQERNEPIFPALIYSSTMVWLVNMAD
TDRPKRSSTDAAPPQQETEAVASPTPSSLSQDDGGFTPSWVSQQEHQLGTLQSTEQSRQEIQEMPSARPAAEDDEERGVKLGLGDFIFYSMLVGKASATA
SGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPISIFFGLVFYFATDNLVQPFMDKLALHQFYI
>tr|G3NNZ1|G3NNZ1_GASAC Uncharacterized protein OX=69293 OS=Gasterosteus aculeatus (Three-spined stickleback). GN= PE=4 SV=1
MANHVEDIEMSNESVMKESSCFRH-----TAAHSCPG-------NGSGPEQNGQPGAAPPRVVETEEDEDEELTLKYGAKHVIMLFVPVTLCMVVVVATI
KSVSFFTQKDGQLIYTPFSEDTDTMGQRALNSILNASIMITVIIVMTLVLVLLYKYRFYKVIQGWLFLASLLMLFSFSFIYLKEVFKTYNLATDYFTVAI
IIWNFGVVGMLCIHWTGPLRLQQAYLIMISALMALVFVKYLPEWTGWLILGAISVYDLLAVLCPKGPLRILVETAQERNEPIFPALIYSSTMVWLVNMAD
TEWPPRRSSAAAPPLQEAEAAGSPPPSSPPGDDGGFSSSWVDHQQHQLGPLQTTDETRREIQELPSARPPVEDDEERGVKLGLGDFIFYSMLVGKASATA
SGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPISIFFGLVFYFATDNLVQPFMDQLALHQFYI
>tr|H3AT04|H3AT04_LATCH Uncharacterized protein OX=7897 OS=Latimeria chalumnae (West Indian ocean coelacanth). GN= PE=4 SV=1
MTELSASLPVYQQGQLTED---PDSRQTNSKKKSQNESGERRPNESRNAESNGEPQAASQRVVVSDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATI
KSVSFYTKKNGQLIYTPFSEDTDTVGQRALNSILNAAIMISVIIVMTLLLVLLYKCRCYKVIHGWLIISSLLLLFFFSFIYLGEVFKTYNVAMDYITVAL
IIWNFGVVGMICIHWKGPLRLQQAYLIMISALMALVFIKYLPEWTGWLILVVISVYDLIAVLCPKGPLRMLVETAQERNEPIFPALIYSSTMVWLVGMAD
PDPEARRKEPEDSRREAEASTNHT-ASATPADDGGFTQDWVQQQNETLGDMHSTMETRAAVQALPNNNPIPEDPEESTYSFALG---LLSYLMGASSQKS
NGGRNVLVQIFLAVSLGLCLTLLLLAIFKKALPALPISITFGIIFYFATDNLVRPFMDQLAFHQFYI
>tr|H3CBJ2|H3CBJ2_TETNG Uncharacterized protein OX=99883 OS=nigroviridis). GN= PE=4 SV=1
---------MNQETGGVPEPAVQPQEVSVTRARSRGG----GGHGGGGPEQNGQPPAPAAHAVETDEDEDEELTLKYGAKNVIMLFVPVTLCMVVVVATI
KSVSYYTKNDEQLIYTPFPENTDTVAERALNSVLNATIMITVIIVMTLVLVVLYKYRCYKVIQGWYIY--LKYVCNASALSDREVFKNYNLAMDYFTIAI
IIWNFGVVGMMCIHWKGPLRLQQAYLIMISALMALVFIKYLPEWTSWLILAVISVYDLLAVLCPKGPLRILVETAQERNEPIFPALIYSSTMVWLVNVAD
SDGPNRSSLDAAPTHPEAET-SSPTPSSPSLDDGGFTPSWVSQQEHQLGTLQSTEQSRREIQEMPSARPPAEDDEERGVKLGLGDFIFYSMLVGNASATA
SGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPISIFFGLVFYFATDNLVQPFMDKLALHQFYI
>tr|G3Q8S2|G3Q8S2_GASAC Uncharacterized protein OX=69293 OS=Gasterosteus aculeatus (Three-spined stickleback). GN= PE=4 SV=1
MNASDSEEDYDERTALVPENPVLPSYRPEPDNPP--D-PPTKRFG-VSGRAGTAPVDGGGGGSDQEADEEE-LTLKYGAKHVIMLFIPVTLCMLVVVVTI
KSVSFYTEKTNQLIYTPFTENTASVGRRLLNSVLNTIIMISVIVVMTIFLVVLYKYRCYKFIHGWLILSSLMLLFWLSFMYLSEVFKTYNLAVDYPTVGV
IIWNFGTVGMICIHWKGPLQLQQAYLILISALMALVFIKFLPEWSAWLILGAISVYDLVAVLSPKGPLRMLVETAQERNEPIFPALIYSSAMMWTVGMA-
-SPPEAQRSGQETGRASQ--------------APTYERECRDPQGCWFEPEEAEQSSRRAEPENRQSQLPEDDLEDRGVKLGLGDFIFYSVLVGKAAATG
-GDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFSTGFLVQPFMDNLAAHQFYI
>tr|F1Q8Y6|F1Q8Y6_DANRE Presenilin-1 OX=7955 OS=Danio rerio (Zebrafish) (Brachydanio rerio). GN= PE=2 SV=1
MADLVQ---NAANNVLNDGMDTSRHTSSTAAPPSRNE-----------VELNGQPPTAPPQVVTSEEDEDEELTLKYGAKHVIMLFIPVTLCMVVVVATI
KSVSFYTQKDGQLIYTPFREDTETVGQRALHSMLNAIIMISVIVVMTLVLVVLYKYRCYKVIQAWLFFSNLLLLFFFSLIYLGEVFKTYNVAMDYFTLAL
IIWNFGVVGMICIHWKGPLRLQQAYLIMISALMALVFIKYLPEWTAWLILAAISVYDLLAVLCPKGPLRILVETAQERNEAIFPALIYSSTMVWLFNMAD
SAETRNNSSHPVPQQENQ--VVAMAPTAQPEDDGGFTPAWVDHQQHQLGPMQSTEESRRQIQEMPSARPPPPADEERGVKLGLGDFIFYSMLVGKASATA
SGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFATDNLVRPFMDQLAVHQFYI
>tr|G6D0V3|G6D0V3_DANPL Uncharacterized protein OX=13037 OS=Danaus plexippus (Monarch butterfly). GN= PE=4 SV=1
MSDTGSDHTALMDGHIAEARPDREVAERIARKRKTKS-DTTRNYGTVEQPDSRQTGAG-----EETADQSEEMELKYGARHVIKLFVPVTLCMMVVVATI
SSITFYSVKDVYLAYTPFHEESPHAATKVWNALANSMILLCVIAFMTVLLIVLYKKRCYKVIHGWLILSSLMLLFLFSYLYIEEALRAYNIPLDYITIFF
VMWNFGVMGMITIHWKGPLRMQQAYLIFIAALMALVFIKYLPEWTTWAVLAVISIWDLIAVLTPKGPLRILVETAQERNEPIFPALIYSSTVMYMLAAVE
GSSNSEG--------NVN--SGGD-----GDGEGGFDNAWRERAAAGA-PLRVEASARYVT------SQ-DAD-DEKGVKLGLGDFIFYSVLVGKASSY-
-GDWNTTLACFMAILIGLCLTLLLLAIFKKALPALPISITFGLIFYFATRSIAKPFADALAADQVFI
>tr|E9FSB0|E9FSB0_DAPPU Putative protease presenilin OX=6669 OS=Daphnia pulex (Water flea). GN= PE=4 SV=1
MSSPRSS---------TSSNPPENGASLIPNERPSRS-NTNPALQERQQIPRELS--------DQDELEDEE-ELKYGAAHVIKLFVPVSLCMMVVVATI
SSVTYYTQKGIYLVYTPFHEDSPDTGTKVWNAVANAAILLGVIVVMTVFLIMLYKYRCYKIIHGWLIMSSLMLLFIFAYLYLGEVLRTYNIPLDYISLLF
IMWNFGVVGMIAIHWKAPLHLQQAYLIFVAALMALVFIKYLPEWTTWVVLGVISIWDLVAVLSPRGPLRILVETAQSRNEPLFPALIYSSTVAYMAVMAT
DQSSTSN-------STSN--NETAANGPRSPTDGGFTPAWNQEAEQRTEAHRVQAAAEAPRQPVTEEID-DDE-EERGIKLGLGDFIFYSVLVGKASSY-
-GDWNTTIACFVAILIGLCLTLLLLAIFRKALPALPISITFGLVFYFATSKLVAPFADSLTAQQVFI
>tr|B5X1U6|B5X1U6_SALSA Presenilin-2 OX=8030 OS=Salmo salar (Atlantic salmon). GN= PE=2 SV=1
MSTSDSDEDYNERTALVAEIPSVPSYQQDPDPQP--D-MEPRRRP-VAPEPAAEPPSLDRSAVEREPEEEEELTLKYGAKHVIMLFVPVTLCMVVVVATI
KSVSFYTEKNGQLIYTPFTEDTDTVGERLLNSVLNTIIMISVIVVMTIFLVVLYKYRCYKFIHGWLILSSLMLLFWFSFMYLGEVFKTYNLAMDYPTVAM
IIWNFGAVGMICIHWKGPLQLQQAYLIAISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMIWMVGMA-
-NPA---RNAEPTNQDTD--------------EEAHQSEGSALARDWVEP-----ETQVSSGMNRSYS-TEDDLEDRGVKLGLGDFIFYSVLVGKAAATG
-GDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFSTDNLVRPFMDNLAAHQFYI
>tr|G0N7M3|G0N7M3_CAEBE CBN-SEL-12 protein OX=135651 OS=Caenorhabditis brenneri (Nematode worm). GN= PE=4 SV=1
---------------------MPYSREPQDGGG-NTS-ASSHTTYGTNLISNR----S-----EPEENQVEEAELKYGASHVIHLFVPVSLCMALVVFTM
NTITFYSQNNGRLLYTPFVKETDSIVEKGLMSLGNALVMLSVVIVMTVLLIFFYKYKFYKLIHGWLIISSFLLLFLFTAIYVQEVLKSFDVSPSVILVLF
GLGNYGVLGMMCIHWKGPLRLQQFYLITMSALMALVFIKYLPEWTVWFVLFVISVWDLVAVLTPKGPLRYLVETAQERNEPIFPALIYSSGIIYPYVLVT
AVKNSEEGTEMPTTSSASSSQPS-----------NVPKKTTKVKRIPVSSNP--PVARVERPIVNVEPVQHEDQEEKGVKLGLGDFIFYSVLLGKASSY-
-FDWNTTLACYVAILIGLCFTLVLLAVFKRALPALPISIFSGLIFYFCTRWIITPFVTKFTQNCLLY
>tr|H3CB70|H3CB70_TETNG Uncharacterized protein OX=99883 OS=nigroviridis). GN= PE=4 SV=1
-----------------------------------------------------GPPESAGSDQEVDPDEEE-LTLKYGAKHVIMLFVPVTLCMVVVVTTI
KSVSFYSEKSKQLIYTPFSEDTSSVGQRLLHSVLNTVIMISVIVVMTVFLVVLYKYRCYKFIHGWLILSSLMLLFWFSFMYLGEVFRTYNVAVDYPTVAL
LLWNFGAVGMVCIHWKGPLQLQQLYLILVSALMAL-FIKYLPEWSAWVILGAISVYDLVAVLSPKGPLRMLVETAQERNEPIFPALIYSSAMMWTVGMA-
-KPTEAPPPGAETGEEGTGTREEGPRPLPEAEEEDPGPASRGSESCRLRPGRSWKFLELQTPEQVWTRLTD---QQGGVKLGLGDFIFYSVLVGKAAATG
-GDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFSTDFLVQPFMDHLAAHQFYI
>tr|H2TY48|H2TY48_TAKRU Uncharacterized protein OX=31033 OS=Takifugu rubripes (Japanese pufferfish) (Fugu rubripes). GN= PE=4 SV=1
MNSSDSDDDYNERSALVPQNPAVPSYRPTVDPRSPIAQPCKQM--------AGNRREGPPDSGGSDQDDDEELTLKYGAKHVIMLFIPVTLCMVVVVTTI
KSVSFYSESDQQLIYTPFTENTSSVGRRLLNSVLNTIIMISVIVVMTIFLVVLYKYRCYKFIHGWLILSSLMLLFWFSFMYLGEVFKTYNVAMDYPTVGL
LIWNFGAVGMICIHWKGPLQLQQIYLILISALMALVFIKYLPEWSAWVILGAISVYDLVAVLSPKGPLRMLVETAQERNEPIFPALIYSSAMMWAVGMAK
PVDAPHSGRETSKQYRI------------------SGSP--------INPPRAAPVHKVEA----L---PSGGDQAGGVKLGLGDFIFYSVLVGKAAATG
-GDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPISITFGLIFYFSTDFLVQPFMDNLAAHQFYI
>tr|Q6P0Y0|Q6P0Y0_DANRE Presenilin2 OX=7955 OS=Danio rerio (Zebrafish) (Brachydanio rerio). GN= PE=2 SV=1
MNTSDSEEDYNERSALVQESPTVPSYNQDNAMSLPQDTDSKRSGA-----VRSRSASGSGDAGPVDREEEEELTLKYGAKHVIMLFIPVTLCMVVVVATI
KSVSFYTESGQRLIYTPFEEDPNSVGQRLLNSVLNTLVMISVIVFMTIILVLLYKYRCYKFIHGWLILSSLMLLFWFSFMYLGEVFKTYNVAMDYPTLLM
IIWNFGVVGMICIHWKGPLRLQQAYLIVISALMALIFIKYLPEWSAWVILGAISIYDLIAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWMVGMAD
SNNPDSAGERRGGV-----------------------RT--------QEGVESEPQAGRRQ----YSA-EEDLEEDRGVKLGLGDFIFYSVLVGKAAATG
-GDWNTILACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFSTDNLVRPFMDSLAAHQYYI
>sp|O12976|PSN1_XENLA Presenilin alpha OX=8355 OS=Xenopus laevis (African clawed frog). GN= PE=2 SV=1
MNDT------SERRSNENESQS-----------------------------NGQTQSSSQQVLEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATI
KSVSFYT-FDGQLIYTPFTEDTESVGQRALNSILNATIMISVIIVMTILLVVLYKYRCYKVIHGWLIISSLLLLFFFSYIYLGEVFKTYNVAVDYITLAL
LIWNFGVVGMICIHWKGPLLLQQAYLIMISALMALVFIKYLPEWTTWLILAVISVYDLVAVLSPKGPLRMLVETAQERNETLFPALIYSSTMIWLVNMAD
GDPGLKQSASTKTY-----------------------NT--------QAPTAH-PRSDSAA----SDD-NGGFDTTRGVKLGLGDFIFYSVLVGKASATA
SGDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFATDYLVQPFMDQLAFHQFYI
>tr|G3Q8R8|G3Q8R8_GASAC Uncharacterized protein OX=69293 OS=Gasterosteus aculeatus (Three-spined stickleback). GN= PE=4 SV=1
MNASDSEEDYDERTALVPENPVLPSYRPEPDLNPPLDPPTKRFG------VSGRAGTAPVDGGGSDQEDEEELTLKYGAKHVIMLFIPVTLCMLVVVVTI
KSVSFYTETNQTLIYTPFTENTASVGRRLLNSVLNTIIMISVIVVMTIFLVVLYKYRCYKFIHGWLILSSLMLLFWLSFMYLSEVFKTYNLAVDYPTVGV
IIWNFGTVGMICIHWKGPLQLQQAYLILISALMALVFIKFLPEWSAWLILGAISVYDLVAVLSPKGPLRMLVETAQERNEPIFPALIYSSAMMWTVGMAS
PPEAQRSGQETDEE-----------------------AE--------QSSRRAEPENRQSQ----LFP-EDDLEEDRGVKLGLGDFIFYSVLVGKAAATG
-GDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFSTGFLVQPFMDNLAAHQFYI
>tr|I3JIE1|I3JIE1_ORENI Uncharacterized protein OX=8128 OS=Oreochromis niloticus (Nile tilapia) (Tilapia nilotica). GN= PE=4 SV=1
MNASDSDEDYNERSALVRESPALPSYIPDSDLTPPNGTPTKRLKA----GISRRPGAAAADGGGSDPEEEEELTLKYGAKHVIMLFIPVTLCMVVVVATI
KSVSFYTETDQQLIYTPFTENTSSVGRRLLNSVLNTIIMISVIVVMTIFLVVLYKYRCYKFIHGWLILSSLMLLFWFSFMYLGEVFKTYNLAMDYPTVGV
IIWNFGAVGMICIHWKGPLQLQQAYLILISALMALVFIKYLPEWSAWVILGAISVYDLVAVLSPKGPLRMLVETAQERNEPIFPALIYSSAMVWTVGMAS
PNETQRS--EPDEE-----------------------AE--------QSDGRAEPPSRHSR----LLP-EDEMEEDRGVKLGLGDFIFYSVLVGKAAATG
-GDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFSTDFLVQPFMDNLAAHQFYI
>tr|J9JRM4|J9JRM4_ACYPI Uncharacterized protein OX=7029 OS=Acyrthosiphon pisum (Pea aphid). GN= PE=4 SV=1
-----------------------------------------------------MAAAAPRETSRRDSLAQEEETLKYGAEHVIKLFVPVSMCMLVVVATI
NSVSFYN-KDVYLVYTPFHETSPEPSTKVLNAVANSLILMSVVIIMTVFLIALYKYRCYKLIHGWLIMSSLLLLSMFTCLYIEEILHTYNIPMDYITFFL
IIWNIGMLGMICIHWKGPLRLQQSYLIFIAALMALVFIKYMPEWTTWVVLFVISIWDLIAVLTPRGPLRILVELAEERNEQIFPALIYSSTVVYMMNRSD
SIDSTTDSQNG---F---------------------TRT--------WVEEHQQPQTEEVR----VCR-RLMDEDDKGVKLGLGDFIFYSVLVGKASSY-
-GDWNTTLACFVAILIGLCLTLLLLAIFRRALPALPISITFGLVFYFATRGLVKPFADMLASQQVFI
>tr|L7MIX2|L7MIX2_9ACAR Putative presenilin OX=72859 OS=Rhipicephalus pulchellus. GN= PE=2 SV=1
----------------------------------------------------GRDSGGAAVASGRGREEEEEEELKYGAKHVIKLFVPVSLCMLVVVATI
SSINFYRHTNTYLVYTPFTDQTVDTGTKVWQSFANAFILMGVIVVMTILLIVLYKFRCYKVIHGWLILSSLLLVFLFAYIFLGEVLRAYNVPMDYPTVVF
AMWNFGVVGMISIHWKGPLLLQQAYLILVSALMALVFIKYLPDWTAWVVLGVISVWDLIAVLCPKGPLRILVETAQERNEPIFPALIYSSAMAWCVTMAD
RDPF-YTNQNQLGA---Q-----SDASSAASTDSPVEVEQPRMERTRRRSQRGSGTLAGATDNASDLPHQ---EEERGVKLGLGDFIFYSVLVGKASSY-
-GDWNTTVACFVAILIGLCLTLLLLAIFKKALPALPISITFGLIFYFATSSLVQPFADSLASEQVFI
>tr|Q8WS58|Q8WS58_BRAFL Presenilin OX=7739 OS=Branchiostoma floridae (Florida lancelet) (Amphioxus). GN= PE=4 SV=1
----------------------------------------------------AGDGGEDHGIRHREDEEEEDTTLKYGAKHVIMLFAPVSLCMAVVVATI
SSITFYTEKNGYLIYTPFHEEGASTASKVGDSLANGAIMVGVILVMTVFLVILYKYRCYKFIHGWLILSSLMLLFLFAYIYLGEVLQAYNIPCDYITLAI
VMWNFGAVGMVCIHWKGPLLLQQAYLIVISALMALVFIKYLPDWTTWFILGAISLYDLVAVLCPKGPLKVLVETAQERNEPIFPALIYSSTMMWFVGMAD
SDPEAKKKKKKRRA---D-----GDPAVGGEEEGGFGPDWNESSDASVNSEDARQNLSGRLSPSGNQQMEDEDEEERGVKLGLGDFIFYSVLVGKASSN-
-GDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPISITFGLIFNFATANLVTPFTDALASQQVYV
>tr|K7J3W8|K7J3W8_NASVI Uncharacterized protein OX=7425 OS=Nasonia vitripennis (Parasitic wasp). GN= PE=4 SV=1
----------------------------------------------------HPDPDPPGNPVDHNDQDEVEEELKYGAVHVIKLFVPVSLCMLVVVATI
SSIGFYTTKGVYLVYTPFHEETNDSGTKAWQAVANSLILMAVVVFMTVILIVLYKYRFYKTIHAWLIISSLILLFLFTSLYCEEVLKAYNIPMDIITLAI
GLWNFGVVGMVCIHWQGPLSLQQAYLIFIAALMALVFIKYLPEWTAWAVLAVISIWDLIAVLTPKGPLRILVETAQERNESIFPALIYSSTVMYAATMAN
GDTAASPARVQPQT---Q-----RSSVSSDTEEGGFTREWVETDRSARRAQEVRTNSRGSAEVNGASQQAQQQQEERGVKLGLGDFIFYGVLVGKASSY-
-GDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPISIAFGLIFYFATRVIVAPFADSLASEQIFI
>tr|F4X309|F4X309_ACREC Presenilin-like protein OX=103372 OS=octospinosus echinatior). GN=G5I_12697 PE=4 SV=1
----------------------------------------------------NRRGTSGSNNQNRRRRDEEEEELKYGAAHVIKLFVPVSLCMLVVVATI
SSVHFYTTKGMYLVYTPFHEDSSDTSTKVWQAFANSLILMSVIVVMTVILIILYKYRFYKVIHGWLIISSLLLLSMFSALYCEQMLKAYNIPMDLFTLAI
GLWNFGVVGMICIHWQGPLQLQQAYLIFISALMALVFIKYLPEWTAWVVLGVISIWDLIAVLMPKGPLRILVETAQERNESIFPALIYSSTILYSATMAS
GDTAASPTRGQTDN---Q-----NNPVSGDTEEGGFSPEWVETERSTRRVQEVRSAIRESARQQDNRPREQRQEEERGVKLGLGDFIFYSVLVGKASTY-
-GDWNTTLACFVAILIGLCLTLLLLAIFKKPLPALPISTTFGLTFYFATRAIVAPFADSLASEQVFI
>tr|K1PKB7|K1PKB7_CRAGI Presenilin-2 OX=29159 OS=Crassostrea gigas (Pacific oyster) (Crassostrea angulata). GN= PE=4 SV=1
----------------------------------------------------RGNRTSAQRRPARSEEEEEDDTLLYGAKHVIMLFVPVSLCMAVVVATI
SSVTFYTEKGGYLVYTPFHDADADTGTKVWQSVANALILLGVICVMTIVLLLLYKFRCYKVIHGWLIASSLMLLFLFSYIYLGVVLQAYNVAMDYITVAL
LMWNFGVVGMICIHWKGPLFLQQAYLIVISALMALVFIKYLPDWTTWVVLGVMVIWDLVAVLCPKGPLRILVETAQERNEPIFPALIYSSTMIWVVGMAD
DGSDKKKKKSKKKP---E-----AATQVEAELDGGFLEE----TEETARAVRAAGDTEGQRTNSPRNPEEEEEEEERGVKLGLGDFIFYGVLVGKASSN-
-GDWNTTLACFVAILIGLCFTLLLLAIFRKALPALPISITFGLIFNFTTSLLVQPFADRLSASQVYI
>tr|H3HYW0|H3HYW0_STRPU Uncharacterized protein OX=7668 OS=Strongylocentrotus purpuratus (Purple sea urchin). GN= PE=4 SV=1
----------------------------------------------------ERD-------PPPMEEEEEDEMLKYGAKHVIMLFVPVSLCMLVVVATI
STVSFYTESGDYLIYTPFHEKSDQAGTKAWNALANALIIIGIVLIMTIFLVVLYKYRCYKVIHGWLVLSSLLLLFFFTFFYLQELLVTYNIPMDYFTIAV
IMWNFGMVGMVSIHWKGPLRLQQLYLIVISALMALIFIKYLPEWTLWTILAAIAVYDLFAVLCPKGPLRMLVETAQERDEQIFPALIYSSTMVWLVGMAD
DSPPPAKQEPPVEE---H-----TAETVSGQEDGGFDTVFTE-ANSSVTSEDRRRALRNN-GPSNRQPPVEEEEEERGVKLGLGDFIFYSVLVGKASAS-
-GDWTTTIACFVAILIGLCLTLILLAIFKKALPALPISIAFGLVFYFCTSNLVFPFTDELASQQVYI
>tr|B1AP22|B1AP22_HUMAN Presenilin-2 CTF subunit OX=9606 OS=Homo sapiens (Human). GN= PE=2 SV=1
----------------------------------------------------DPDRYVCSGVPGRPPGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATI
KSVRFYTEKNGQLIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLLFLFTYIYLGEVLKTYNVAMDYPTLLL
TVWNFGAVGMVCIHWKGPLVLQQAYLIMISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWTVGMAK
LDPSS----------------------------GALQLPYDPEEEDSYDSFGEPEVFE---PPLTGYPGELEEEEERGVKLGLGDFIFYSVLVGKAAAS-
-GDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI
>tr|I6TQW0|I6TQW0_BOMMO Presenilin isoform A OX=7091 OS=Bombyx mori (Silk moth). GN= PE=2 SV=1
----------------------------------------------------PRVPAAPVE------PQIEELELKYGARHVIKLFVPVTLCMLVVVATI
SSINFYSVKDVYLAYTPFHEESPYASTKVWNALANSMILLCVIALMTVLLIVLYKKKCYKTIHGWLILSSLILLFLFSYLYIEEALIAYNIPMDYITLGF
VLWNFGVMGMIVIHWKGPLRLQQAYLIFIAALMALVFIKYLPEWTTWAVLAVISIWDLVAVLTPKGPLRILVETAQERNEPIFPALIYSSTVMYCAPGAA
GERELRPLQPHGTV---E-----GEGRDGTEAGGGFDAAWREREGAAPRRLRVDPRYVTRLDPPHAPPHADL-DEEKGVKLGLGDFIFYSVLVGKASSY-
-GDWNTTLACFVAILIGLCLTLLLLAILKKALPALPISITFGLIFYFATRSVVKPFADALAAEQVFI
>tr|E0VJ41|E0VJ41_PEDHC Putative uncharacterized protein OX=121224 OS=Pediculus humanus subsp. corporis (Body louse). GN=Phum_PHUM238320 PE=4 SV=1
----------------------------------------------------TRSTNNGNQANDEWQ---EELELKYGAKHVIKLFAPVSLCMLVVVATI
SSIKFYTTSDMYFVYTPFHETDSNPGTKAWNAVANSLILIAVIVVMTIVLIILYKKRCYKTIHGWLIASSLMLLFLFSYLYLEEVLRAYNIPMDYFTLTI
IMWNFGVVGMICIHWKGPLLLQQAYLIFIAALMALVFIKYLPEWTAWVVLAVISIWDLIAVLTPRGPLRILVETAQERNEQIFPALIYSSTFMYNVNMTS
EETK-NPTSSLKES---N-----STRNFEEDPESGFVRGWMNPQRAKRRNEEIQVRFHPQQSEGHSNPPVTNAEEERGVKLGLGDFIFYSVLVGKASSY-
-GDWNTTVACFVAILIGLCLTLLLLAVFRKALPALPISITFGLIFYFTTKKIVKPFADNLAGEQIFI
>tr|F1L7X7|F1L7X7_ASCSU Presenilin-1 OX=6253 OS=Ascaris suum (Pig roundworm) (Ascaris lumbricoides). GN= PE=2 SV=1
----------------------------------------------------SRRSSSVRADDANADANMQHDVTRYTPKHALKLFAPVSCCMTLVFLHS
KFVLHHKQLDAYAPYLPFKEEEQTGWDALWKSIIIAAMFVGLIIAATSLIVFAYFMKWYKAILAMVMLNCFLLFSLLTFDLLNSIVTIYNIHGDYVTLVL
FMYNYGTLGMISIFWTAPLMIQQVYLVMISALVSIMLLHLFPSWAVWTVLGALALWDVVAVLCPFGPLQILIKLSRERNEPIMPALIYSAGLIY-ETLAL
HSCRGSCTEKPGSS---E-----CERQRAQPEEGQMSSASSGKSENPQNTSGTQRSDNNPMPVNDNRRANGRASRSEAIKLGLGDFIFYGVLIGKASE--
-GGILATISCFTAILIGLCATLVFLFIYGRALPALPISIFMGISFYFATHFLIDPFCESVSMHQLIL
>tr|A8X5S7|A8X5S7_CAEBR Protein CBR-SEL-12 OX=6238 OS=Caenorhabditis briggsae. GN= PE=4 SV=1
----------------------------------------------------TLTTYGTNLISNRSRNQVEEAELKYGASHVIHLFVPVSLCMALVVFTM
NTITFYSQNNRHLLYTPFVKETDSIVEKGLMSLGNALVMLCVVVFMTVLLIVFYKYKFYKLIHGWLIISSFLLLFLFTTIYVQEVLKSFDVSPSAVTILF
ALGNYGVLGMMCIHWKGPLRLQQFYLITMSALMALVFIKYLPEWTVWFVLFVISVWDLVAVLTPKGPLRYLVETAQERNEPIFPALIYSSGVLYPTALEN
PEESRTTSEQPATT---E-----AAPSTSAGNTGGLQSDSKRTEEAPPAARNQPQNVRERRTPAVQLEPRDDYQEERGVKLGLGDFIFYSVLLGKASSY-
-FDWNTTIACYVAILIGLCFTLVLLAVFKRALPALPISIFSGLIFYFCTRWIITPFVTFVSQNSFLY
>tr|G7Y344|G7Y344_CLOSI Presenilin 1 OX=79923 OS=Clonorchis sinensis (Chinese liver fluke). GN=CLF_100290 PE=4 SV=1
----------------------------------------------------ESYSQGEAPLGASNASFKADELLVFGAKQVIRLFIPVTICMFFVVLVA
TTVDYYASTETYLIYTPFHTPDADLGTRTWQTIANTLIFMSVIIVMTCVLVLLFKYQCYRFIHGWLILTTFMLLFLISFLFFTEIIRAMGIFVDYITMAF
ILWNFGVVGMVVIHWRGPLILQQAYLIFISAQIALMFLKYLPKWTCWVLLGALAVWDLVAVLCPRGPLRMLVEMAHEREQPLFPALLYSTTAVY-TASTS
ANANGSEAEGSDSN---A-----EVPSTGDQRNSDLPSANVTTERHLRRMTESIADHSNSTDAASRWRHLLRDREERGVKLGLGDFVFYSLLIGRAALD-
-GDVITVATCYVAILVGMCVTIIVLGITRRALPALPVSVACGILFYFVTSTVISPFLQVVAVGRLVF
>tr|F6RA92|F6RA92_CIOIN Uncharacterized protein OX=7719 OS=Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis). GN= PE=4 SV=1
----------------------------------------------------ANQSNNTTDSPARRIAEDAEEELRYGASTVISLFIPVTLCMLVVVATI
TSVSYYTDQSQFLVYTPFHTTNAAPAQVVWESIANSLIMIGVIVVMTVFLVLLYKYRCYKVIHGWLILSTLLLVFLFAYLYLAEVLRAYNTAVDYITVVI
VLWNFGVVGMICIHWKGPLLLQQAYLIIVSSLMALVFIKYLPEWTAWVILGFISIYDLLAVLCPKGPLRMLVETAQSRNESLFPALIYSSGMMWTVGMAQ
NAPAPQQPRGNGSF---S-----TLGNTSSTSQGGFDVAWQRRNRNSGEVIITSNETRNQARQQLGPPPESEEAEDKGVKLGLGDFIFYSVLVGKASAT-
-GDWNTTIACFVAILIGLCLTLILLAIYRKALPALPISITFGLVFYFSTDYVVRPYMDSINSAQVYL
>tr|B7Q2V0|B7Q2V0_IXOSC Presenilin, putative OX=6945 OS=Ixodes scapularis (Black-legged tick) (Deer tick). GN=IscW_ISCW020583 PE=4 SV=1
----------------------------------------------------GTEVDLQPASGGGGRTEEEEEELKYGAKHVIRLFVPVSLCMLVVVATI
SSISFYRHTNTYLVYTPFTDQTVDTGTKVWQSFANAFILMGVIVVMTILLILLYKFRCYKVIHAWLIVSSLLLVFLFAYIYLGEVLRAYNVPMDYLTVAL
VMWNFGVVGMISIHWKGPLLLQQAYLILVSALMALVFIKYLPDWTAWVVLGVISVWDLIAVLCPKGPLRILVETAQERNEPIFPALIYSSAMVWNVTMAD
RDPF-YSSQNQHAS---Q-----SDASSGTSRRP--CSTFPRMSRSRRRSQRGSGTLAGSAPEVDDLPRQ---EEERGVKLGLGDFIFYSVLVGKASSY-
-GDWNTTIACFVAILIGLCLTLLLLAIFKKALPALPISITFGLIFYFATSSLVQPFADSLAGEQVFI
>tr|E4WQI5|E4WQI5_OIKDI Whole genome shotgun assembly, reference scaffold set, scaffold scaffold_1 OX=34765 OS=Oikopleura dioica (Tunicate). GN=GSOID_T00000100001 PE=4 SV=1
----------------------------------------------------PVDRVSESSTSENESSSAQDTELKYGAEAVINLFIPVTACMIFVIASV
QCLSSYSGQQKQFIYTPFHPDDDSAGTIIWQTVANSLIMISVIAVMTFVLVLLYKYECNMLLGGWLIFSTMTLIFMFGYFYLQQILKVNNAALDWVTLGI
VMWNFGIVGIICIHWKGPLFLQQCYLIISAALMALIFIKMLPNWTTWLILAFLSIWDLIAVLCPYGPLNMLLQLANDREDELFPALIYSSG----AGIAV
---------PTVMV---T-----TSA-------GTFLAPLLGMETSDPSPQEEVQVRQPRSQRSSERTRT---ERREGVKLGLGDFIFYSVLVGKASQL-
-HDWNITLACILSILVGLSTTLIILAFFKKPLPALPISLTLGLIFYFTTTYVIAPFMDLCIMKQVFL
>tr|B7QGI2|B7QGI2_IXOSC Presenilin, putative OX=6945 OS=Ixodes scapularis (Black-legged tick) (Deer tick). GN=IscW_ISCW022390 PE=4 SV=1
-------------------------------------------------------------------KMCHSMTAQYRMRQVITLICALSICMASVACLV
RILKPSKNDG-MQPYVRYPVEYDAEPVLLMNSFANAFSFLSMIMIVNCTLVLLYKGGYTNVIKAWLMTGSGVLLFVVTYYYMGRCVYYFNFPMDHLSCSF
IVWNIGMTGMGTLYYKGPFVMHQGFVIYVSILMAVVLEESFPEWTAWILMILVSLWDMFAVLCVIGPLRMLIETAHERNEPLFPALLFSTSSAWCYDLSA
QTPTNAEKLPRRLL---N-----FRG-STNTED-SFVVSRMKA-QEIRRQEDVLHHHHTHQPRHHRQRRQAAAPEDTGMKMGLGDFIFYSILVGKASRH-
-GTVSAVVICYIYVVIGIILTLALLVIAQKPVPALPLSISLGMFAYFSTISFVEPFMEETGVLSL--
>tr|L5M1J1|L5M1J1_MYODS Papilin OX=225400 OS=Myotis davidii (David's myotis). GN=MDA_GLEAN10017545 PE=4 SV=1
----------------------------QNDSRERHEHNERRRRGNPEPLSNGGPQGNTLQVVEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATI
KSVSFYTRKDGQLIYTPFTEDTETVGQRALHSILNAAIMISVIVVMTILLVALYKYRCYKGPTGAIAASSLKLPFTISACALREVFKTYNVAVDYITIAL
LIWNFGVVGMIAIHWKGPLRLQQAYLIMISALMALVFIKYLPEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAK
GDPEAQRKVSKNSNYNEQNTGSEPQNPVTESDDGGFSEEWEAQRDSRLGPHHSTTESRSAVQEISSSILASEDPEERGVKLGLGDFIFYSVLVGKASATA
SGDWNTTIACFVAILIA--------------------------------------------------
>tr|J0M7E5|J0M7E5_LOALO Presenilin OX=7209 OS=Loa loa (Eye worm) (Filaria loa). GN= PE=4 SV=1
--------------------------------------------------------------------------------------------MVFVIFTM
NTVGYYTKDGQYLIYTPFTKETDDTGEKLIMSFGNAFVILGVVMTMTILLILLYKFRFYRIISAWLILSSLILLSLFTFMYLQEVFKSYNVPVDYILICV
FIWNYGVMGMICIHWKGPLRMQQGYLIMMSALMALIFIKYLPEWTVWTVLAVISIWDLIAVLCPKGPLRILVETAQERNEPIFPALIYSSGLLYAYTLAT
SNSGNHGSATSSADNSLPSPMRATSGTDQGVANASLNAEEHMDNNSKGSKGGESSRTRVVIADNAEADPDPRFPDEKGIKLGLGDFIFYSVLVGKASSY-
-GDWNTTIACYVAILIGLCFTLILLAVFRKALPALPISIFCGLIFYFCTRGIITPFCTSLSLRHLIY
>tr|H2Z6F8|H2Z6F8_CIOSA Uncharacterized protein OX=51511 OS=Ciona savignyi (Pacific transparent sea squirt). GN= PE=4 SV=1
-----------------------------------------------------------------------------------------TLCMLVVVATI
TSVSYYTSQGQYLVYTPFHTQNAGTAQVVWESIANSLIMISVIVVMTIFLVLLYKYRCYKVIHGWLILSSLLLLFLFAYLYLAEVLRAYNTPMDYITVAV
VLWNFGVVGMICIHWKGPLLLQQAYLIVVSSLMALVFIKYLPEWTAWLILGLISIYDLIAVLCPKGPLRMLVETAQERNEPIFPALIYSSGMMWTVGMAQ
ETSRPNAQVSDVPMVGTKSVGSTDTSSTSGGSEAGFGVSWQRHHDSEVTCCFYLNKYCVVITSNETREH-PEEPEDKGVKLGLGDFIFYSVLVGKASAN-
-GDWNTTIACFVAILIGLCLTLILLAIYRKALPALPISITFGLVFYFSTDYVVRPFMDSINSSQVYL
>tr|H9KD94|H9KD94_APIME Uncharacterized protein OX=7460 OS=Apis mellifera (Honeybee). GN= PE=4 SV=1
--------------------------------------------------------------------------------------------MLVVVATI
SSINFYTTKGMYLVYTPFHEDSADTSTKAWQAVANSLILMSVIVFMTVILIVLYKYKFYKVIHGWLIISSLLLLSMFSMLYCEQVLKAYNIPMDLYTLGL
VLWNFGVVGMICIHWQGPLQLQQAYLIFISALMALVFIKYLPEWTAWVVLGVISIWDLIAVLTPKGPLRILVETAQERNESIFPALIYSSTIMYTATMAT
MTTNDTTASDNTTYTMNNQANNQNNSTSGDAEEGGFTPEWDTHGDRGARRAQEVRENTLSLTERSRQDNRPITEEERGVKLGLGDFIFYSVLVGKASSY-
-GDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPISVTFGLTFYFATRVIVAPFADKLASEQVFI
>tr|O73869|O73869_CYPCA PS1 protein OX=7962 OS=Cyprinus carpio (Common carp). GN= PE=2 SV=1
-----------------------------------------------------------------------------------------TLCVVVVATIK
SVSFYTQKDGQQLIYTPFREDTETVGQRALNSMLNAAIMISVIVVMTLVLVVLYKYRCYKVIQGWLFFSNLLLLFFFSFIYLGEVFKTYNVAMDYFTLAV
IIWNFGVVGMICIHWKGPLRLQQAYLIMISALMALVFIKYLPEWTAWLILAAISVYDLLAVLCPKGPLRILVETAQERNEPIFPALIYSSTMVWLFNMAD
S---AEPRNNSSHPVPQQENQDAVAPTAQPEDDGGFTPAWVNQQQHQLGPMQSTEDSRREIQELPSARPPPEDDEERGVKLGLGDFIFYSMLVGKASAS-
-GDWNTTIACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFATDNLVRPFMDQLAVHQFYI
>tr|E3MA46|E3MA46_CAERE CRE-SEL-12 protein OX=31234 OS=Caenorhabditis remanei (Caenorhabditis vulgaris). GN= PE=4 SV=1
--------------------------------------------------------------------------------------------MHF-----
-NVAYM------VLYTPFVKETDSIVEKGLMSLGNALIMLLVVVFMTVLLIVFYKYKFYRVIHGWLIVSSCLLLFLFTTIYVQEVMKSFDISPSAVLVLF
GLANYGVVGMMCIHWKGPLLLQQFYLITMSALMALVFIKYLPEWTVWFVLFVISVWDLVAVLTPKGPLRYLVETAQERNEPIFPALIYSSGVIYPYVLAV
ENPGESREPREPREQPTDTPAPDTGAKRAKVKRVAQKVQIETQSTSQGEGSGGVRVERVPTRPVQQEPPMDDFQEERGVKLGLGDFIFYSVLLGKASSY-
-FDWNTTIACYVAILIGLCFTLVLLAVFKRALPALPISIFSGLIFYFCTRWIITPFVTHVSQNCLLY
>tr|G1LR72|G1LR72_AILME Uncharacterized protein OX=9646 OS=Ailuropoda melanoleuca (Giant panda). GN= PE=4 SV=1
-------------------------------------------------------------------GLEEELTLKYGAKHVIMLFVPVTLCMIVVVATI
KSVRFYTEKNGQLAFLSFWEGERSVGSRLPQSRTHSLHPFSCSGVNFISLLLLKKWRA-KFIHGWLIMSSLMLLFLFSYIYLGEVLKTYNVAMDYPTLFL
TVWNFGAVGMVCIHWKGPLVLQQAYLIMISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWTVGMAK
LDPSSQGALQLPYDPEME---E------DSYDSFG-EPSYPEV----------------FEPPLPGYPGELEEEEERGVKLGLGDFIFYSVLVGKAAATG
SGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI
>tr|G1P6M0|G1P6M0_MYOLU Uncharacterized protein OX=59463 OS=Myotis lucifugus (Little brown bat). GN= PE=4 SV=1
-------------------------------------------------------------------GLEEELTLKYGAKHVIMLFVPVTLCMVVVVATI
KSVRFYTEKNGQLIYTPFTEDTPSVGQRLLNSVLNTLIMLSVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLLFLFTYIYLGEVLKTYNVAMDYPTLFL
VVWNFGAVGMVCIHWKGPLVLQQAYLIMISALMALVFIKYLPEWSAWVILGAISVYERKAGVSARGSLQREDQTLERRSEGGLPSSASASFLLHGLGSLS
LAPG-QGAGRDPEDP--E---E------DSCDSLG-EPSYPEV----------------LEPPLPGSPGELEEEEERGVKLGLGDFIFYSVLVGKAAATG
SGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISIAFGLIFYFSTDNLVRPFMDTLASHQLHI
>tr|B4KY37|B4KY37_DROMO GI13394 OX=7230 OS=Drosophila mojavensis (Fruit fly). GN= PE=4 SV=1
----------------------------------------------------------------PGQPAEEEQGLKYGAQHVIKLFVPVSLCMLVVVATI
NSISFYNSTDVYLLYTPFHELSPEPSIKFWNALGNSLILMSVVVVMTILLIVLYKKRCYRVIHGWLILSSFMLLFIFSYLYLEELLRAYNIPMDYPTAVL
IMWNFGVAGMIAIHWQGPLRLQQGYLIFVAALMALVFIKYLPEWTAWAVLAAISVWDLIAVLSPRGPLRILVETAQERNEQIFPALIYSSTVIYYMGTYA
PEESSSPSNSTATTRTTHASSTSRTQAAAEEEAAGFTQEWSANLNNRVARVQSTGNPRRANRTAPEQ-QQPEPQEERGIKLGLGDFIFYSVLVGKASTY-
-GDWTTTIACFVAILIGLCLTLLLLAIWRKALPALPISITFGLIFCFATNFLVKPFMERLSAKQVFI
>tr|J9I024|J9I024_AEDAE AAEL017503-PA OX=7159 OS=Aedes aegypti (Yellowfever mosquito) (Culex aegypti). GN= PE=4 SV=1
----------------------------------------------------------------PG---DGPSGISCGGRGRTQVWCPARYKTVRPVATI
SSINFYSTKDVYLVYTPFHELSDDTGTKIWNALANSMILMTVIVIMTILLIVLYKKRCYKIIHGWLIMSSLMLLFLFSYLYLEEVLRAYNIPFDYPTALL
LMWNFGVVGMISIHWQGPLRLQQGYLIFIAALMALVFIKYLPEWTTWVVLAVISIWDLIAVLTPKGPLRILVETAHERNEQIFPALIYSSTIMYYMGTSD
PS--DRTIGAAGVGLGGYASGTHPA-----DQSGGFTQEWNNSAEQRVARVQANGNPNRP-RTADSQ-QVPEQAEERGIKLGLGDFIFYSVLVGKASSY-
-GDWNTTIACFVAILVGLCLTLLLLAIFRKALPALPISIFFGLIFCFVTSVIVKPFTEALASDQVFI
>tr|B3M997|B3M997_DROAN GF10339 OX=7217 OS=Drosophila ananassae (Fruit fly). GN= PE=4 SV=1
----------------------------------------------------------------PTNETEEEQGLKYGAQHVIKLFVPVSLCMLVVVATI
NSISFYSSTDVYLLYTPFHELSPEPSVKLWNALANSLILMSVVVVMTILLIVLYKKRCYRIIHGWLILSSFMLLFIFTYLYLEELLRAYNIPMDYPTALL
IMWNFGVVGMMAIHWQGPLRLQQGYLIFVAALMALVFIKYLPEWTAWAVLAAISIWDLIAVLSPRGPLRILVETAQERNEQIFPALIYSSTVIYYMGTYT
PQQSSSPSSSTTTTRATQASGNSHPTLASEAEAAGFTQEWSANLSERVARVQSTGNAQRSNRTAPDQ-SHPDGQEERGIKLGLGDFIFYSVLVGKASSY-
-GDWTTTIACFVAILIGLCLTLLLLAIWRKALPALPISITFGLIFCFATSAVVKPFMENLSAKQVFI
>tr|B0WS38|B0WS38_CULQU Presenilin sel-12 OX=7176 OS=Culex quinquefasciatus (Southern house mosquito) (Culex pungens). GN=CpipJ_CPIJ009724 PE=4 SV=1
----------------------------------------------------------------QE---EEEEGLKYGAQHVIKLFVPVTLCMLVVVATI
SSINFYSTKDVYLVYTPFHELSDDTGTKIWNALANSLILMTVIVIMTILLIVLYKRRCYKIIHGWLIMSSLMLLFLFSYLYMEEVLRAYNIPFDYPTALL
LMWNFGVVGMISIHWQGPLRLQQGYLIFIAALMALVFIKYLPEWTTWVVLAVISIWDLIAVLTPKGPLRILVETAHERNEQIFPALIYSSTIMYYMGTSD
PS--ERAIGSTGTVTTSYGTAHQPAAVRTADQSGGFTQEWADASGQRVTRVQANSNPNRP-RTADSQ-QVPEQPEERGIKLGLGDFIFYSVLVGKASSY-
-GDWNTTIACFVAILVGLCLTLLLLAIFRKALPALPISIFFGLIFCFATSVIVKPFTEALASEQVFI
>tr|Q8WS59|Q8WS59_BRAFL Presenilin OX=7739 OS=Branchiostoma floridae (Florida lancelet) (Amphioxus). GN= PE=4 SV=1
----------------------------------------------------------------RHREDDTEMTLKYGAKHVIMLFAPVSLCMAVVVATI
SSITFYTEKNGYLIYTPFHEEGASTASKVGDSLANGAIMVGVILVMTVFLVILYKYRCYKFIHGWLILSSLMLLFLFAYIYLGEVLQAYNIPCDYITLAI
VMWNFGAVGMVCIHWKGPLLLQQAYLIVISALMALVFIKYLPDWTTWFILGAISLYDLVAVLCPKGPLKVLVETAQERNEPIFPALIYSSTMMWFVGM--
--ADSDPEAKKKKKKKKRGDLDNEAAPAGAEEEGGFGPDWNESRGFQPTRVNSERQAAQNLGRPQQQMEEDEDEEERGVKLGLGDFIFYSVLVGKASSN-
-GDWNTTLACFVAILIGLCLTLLLLAIFKKALPALPISITFGLIFNFATANLVTPFTDALASQQVYV
>tr|Q7PR98|Q7PR98_ANOGA AGAP002957-PA OX=7165 OS=Anopheles gambiae (African malaria mosquito). GN=AgaP_AGAP002957 PE=4 SV=1
----------------------------------------------------------------SGNSSNEEEGLKYGAQHVIKLFVPVTLCMMVVVATI
SSINFYTIKDVYLVYTPFHELTDDTGTKIWNALANSLILMTVIVIMTILLIVLYKHRCYKVIHGWLILSSLLLLFLFSGLYLFEILRAYNVPMDWFTAGL
LVWNFGVVGMISIHWQGPLRLQQGYLIFVAALMALVFIKYLPEWTTWAVLAVISIWDLIAVLTPKGPLRILVETAQERNEQIFPALIYSSTIMYYLGTTD
PD--ERTIGSAGGGAGGYN--NHGP-----DQTAGFTQDWAATANQRVTRVQANNNPSRP-RTAPQL-GGADQAEERGIKLGLGDFIFYSVLVGKASSY-
-GDWNTTIACFVAILVGLCLTLLLLAIFRKALPALPISIFFGLIFCFVTSVIVKPFTEALTLEQVFI
>tr|E2BSL4|E2BSL4_HARSA Presenilin-like protein OX=610380 OS=Harpegnathos saltator (Jerdon's jumping ant). GN=EAI_01626 PE=4 SV=1
----------------------------------------------------------------PRH--DEDAEVEKGVVHVINLFIPVSLCMLVVVATI
SSVNFYTTKGMYLVYTPFHEDSSDTSTKVWQAFANSLILMSVIVFMTVILIILYKYKFYKVIHGWLIISSLLLLSLFSILYCEQVLKAYNIPMDFFTLSI
GLWNFGAVGMICIHWQGPLQLQQAYLIFISALMALVFIKYLPEWTAWAVLGVISIWDLIAVLTPNGPLRILVETAQERNESIFPALIYSSTILYF-----
----TVSYA-----YVQAAGGNNSPYASGDTEEEGFTNEWVETHGERSARVRENGTNRRQQRSIPPP-PPPPPMEERGVKLGLGDFIFYSVLVGKASSY-
-GDWNTTLACFVAILIGLCLTLVLLAICKKALPALPISITFGLTFYFATRVIVAPFADSLASEQVFI
>tr|E9C2Q6|E9C2Q6_CAPO3 Presenilin2 OX=595528 OS=Capsaspora owczarzaki (strain ATCC 30864). GN=CAOG_02639 PE=4 SV=1
------------------------------------------------------------------EEEDEDEELKYGAKEVMALIVPVTLCMAIVVASI
QSITYYAQDSGYLAYIAFKEDSDSGAENFGGAIINALIIVGVILVMTCVLVLLYKYRCYKAIWMWLFLSTVMLLFLFTYIYLELVFDRYNVAMDWVTFAF
VIWNFGCVGVVAVHWKAPLLLQQAYLITTSALLALTLIKHLPEWTTWVLLAAIAVYDLFAVLCPRGPLKVLVETAQERNEPIFPALIYSSTMAWIAVAAV
DKPVPSEDAEEVPQLQAASTQPTGTNAGAAADEDEATNAAEQSQDS-TAPAEDDEGTYSSSSHFHSCSLSCFCTTEHGVKLGLGDFIFYSVLVGKASVS-
-NNWSTILSCFFAILVGLCLTLVLLAIYRRALPALPISIAFGLLFYYVSNEVLVPFNNQLSAVQVFV
>tr|D3B4U3|D3B4U3_POLPA Presenilin family protein OX=13642 OS=Polysphondylium pallidum (Cellular slime mold). GN= PE=4 SV=1
----------------------------------------------------------------DEDDEEGETDLEDFSNMIIAILKPVTITMFLVVWAV
RSINAKNNILGQVGGMLVYNEDDSTGQKIWGSLLNGLVFLVVIVLTTVAFVLLYKYRCLKAIYAWLFLSGILLASMGSYVFM-AMLEANNLALDYITFAF
IMFNFSVGGIIAVFWYAPVLMNQGYLVLISTLMAISISR-LPDWTTWVILSVISIYDLFAVLCPRGPLKVLVETAQERNET-IPALIYNANF--------
-EPPPESIPKPPQQQQQQQSASS-SSSQQARSRRNNNNGGEDQQEDEFGQQQQQQEDDAQV-----DPPIEPEQEKRSLKLGLGDFVFYSVLMGRAAM--
-FDISTVFTCFVAIITGLFATLFLLAIFRKALPALPISIAFGILFYFLTRIFLYPFIETMGLVEVFI
>tr|F4Q1Y3|F4Q1Y3_DICFS Presenilin family protein OX=1054147 OS=Dictyostelium fasciculatum (strain SH3) (Slime mold). GN= PE=4 SV=1
----------------------------------------------------------------EEEDLEEEADLEDFSHMIIAILKPVTITMLLVVWAV
RKLSISNN-LNSVGITVYYNENDSTGEKIWGSLLNGLIFLVTILFTTVCFVFLYKYRCLKAIYTWLFLSGVLLAATGGYIFL-AILQANNLAIDYITFAF
LLLNFSAGGIIAIFWYAPTILNQSYLIIISALMAISFTR-LPSWTTWSILAIVSIYDLFAVLCPKGPLRVLVETAQERNET-IPALIYNANF--------
-DPPPNRVQSPRSTNKSSSNSNN-ENEPLIEGDSDQQQDGDQPQQSQQQDGQEGQEEDIEI-----E---EVGEQRRSLKLGLGDFVFYSVLLGRAAL--
-FDMSTVFTCFVAIVTGLFATLLLLAIFRKALPALPISIAFGILFYFLSSVFLYPFIETLGVYQVFI
>tr|Q4AEI4|Q4AEI4_9METZ Presenilin OX=31330 OS=Ephydatia fluviatilis. GN= PE=2 SV=1
--------------------------------------------------------------------EHDEEILKFGATQVIMLMVPVLICMVLVVATE
ITVSLLQPPSTYLVYTPLREESAGSGVTFLFALVNALIVIGLVVVMTVVLVLLFKFECYRAIQGWLLLSSASLLFVFCSLFFVNILYVHNLLMDWFTFAL
IVWNFGVVGLLVIHWKGPLRLQQAYLIMVCAVAASVLLKYLPNWTTWVLLALISVYDLIAVMCPKGPLRILVNLAKERNMDIFPSLIYSSTMVWTIGMAD
SNEKKDDEEDKDSDGEKESTS-----IERSQQQATLTGEGSQYTAHRDGASASAAVTRNAGAHVQHSEEEEEGEERRGFKLGLGDFIFYSILVGRAAHDS
DGDWVIISSCFVAILIGLCLTSLILGIVRRALPALPISIFFGLMFYFSSRYLIAPFVNVMITTQVF-
>tr|H3FRQ2|H3FRQ2_PRIPA Uncharacterized protein OX=54126 OS=Pristionchus pacificus. GN= PE=4 SV=1
-------------------------------------------------------------------EEEDELELKYGAEHVIRLFVPVSICMALVILTM
KMMSYYSIVQPGFVYTPFHTNADDTSTRVLSGLGNALIMICFIVVMTFGLILLYKFKCYRFIHGWLMMSSLMLLTMFSMVYVSELMKMNNCCVSWPTVLI
GLFNFAAMGMICIHWKGPLLMQQAYLISVSALMALMFIKMLPDWTVWALLFLISVWDLIAVLCPKGPLNMLVKMSQERNEPIFPALIYSSGILLPYTMVE
EQERKHVGEGGETTGERRESQPSTSSSVPSSSTSVLIPAGESKQKRPQV-RRVPPPAREERRVVSESRS-TEEVEERGIKLGLGDFIFYSVLVGKASES-
-ADWNTIVACYVAILVGLCATLLLLAVFKKALPALPISITAGLIFYFSTTFLITPFTTKLMV-----
>tr|H3FRQ2|H3FRQ2_PRIPA Uncharacterized protein OX=54126 OS=Pristionchus pacificus. GN= PE=4 SV=1
-------------------------------------------------------------------PDDDEMDLKYGAEHVIRLFVPVSVCMAVVVLTM
NTVEFYSESDATSLYTPFLDEEDDTSTRVLSALGNAGIMIGVIVVMTFVLILLYKYKCYKCLHGWMISSSFMMLTLISGTYVMHVLENHNWCMSNATALF
GLFNYAAMGMICIHWKGPLLMQQAYLISVSALMALMFIKMLPDWTAFALLVLISIWDLVAVLCPKGPLNMLVKMSQERNEPIFPALIYSSGILLPYTIAG
KNEEVEGGAKG--EEEAAESRQNRSRVGPSSDEEK---GTREKAGCDVVVIRSGAS------QSPEDYEEEEEEEESGVKLGLGDFIFYSVLVGMAVKH-
SADWNTLVACYVAILMGLCATLLLLAVFKKALPALPISITAGLIFYFATSFIITPFTNQLVIHQLT-
>tr|I1G5V3|I1G5V3_AMPQE Uncharacterized protein OX=400682 OS=Amphimedon queenslandica (Sponge). GN= PE=4 SV=1
-------------------------------------------------------------------SEANEEALRFGAQQMILLIFPVFICMALVVAIQ
LSVEKNVTSSGTLIYTPFDEDTASDGFVLLFALANVAIVITLVVVMTIILVCLYN----------------------------EVLQVHYLFIDWPSFLV
LIWNFGGMGVLVIHWKGPLRLQQAYLIFCSALTANIFVKYLPNWTAWILLAAISLYDLIAVLCPKGPLRVLVETARERNETIFPSLIYSTTMVWLVGMAD
RPTNKKK--DKKNTDDTSGSSDGSREGRRDNDDGDDDTDGIEMRSIRAAA-DTNRERRRERQQQQQQEEEEEEEERQGFKLGLGDFIFYSILVGKAAHDS
TGDWVVISSCFVAILIGLCMTIIILGIVRRALPALPISIFCGLIFYFSSQYVIAPFAQVLATTQTFI
>tr|A9VBA9|A9VBA9_MONBE Predicted protein OX=81824 OS=Monosiga brevicollis (Choanoflagellate). GN=29512 PE=4 SV=1
--------------------------------------------------------------------RELELDLKYDAESVLALIKPVSACMIVVIATI
RSITYFSQNDTQFAYTPFESNGESSGERFGGAVLNALIVVGIVIVMTFILVMLYIYEYYKIIYGWLALSALLLLYFFSYQYIEQVLIAHNASIDWITMAF
IIWNFGTVGFIAIFWRSPLAVQQVYLVIVSALMALVLIKNLPDWTTWVLLAAIAIYDLFAVLSPCGPLKCLVEVAQERNQPLFPSLIYSSTMMWTVTMAD
VGDSSSNSATESQPRVADGTEMTSMSSQPRARQGSRAD---SEADDGISTAAPRGETRSTNQAAPASQPQPDDEDDSGVKLGLGDFIFYSVLVGKAATA-
-HEWTTILACYVAILIGLACTLLLLSIFKKALPALPISIFFGLCFFFLTSEVLDPLIDRLNERQIFL
>tr|C0SKM6|C0SKM6_SCHMA Presenilin OX=6183 OS=Schistosoma mansoni (Blood fluke). GN= PE=2 SV=1
-------------------------------------------------------------------SINPDQMLYYGAKQIISLFIPVTVCMLFVVAVA
STVDFYGHTDQYLLYTPFHTPDADIGTQTWQTIANTLIFMSVVVVMTCVLVLLFKYQCYKFIRGWIIMTTIFLLFLISFTFFAEVLRAMGVFVDYITVAF
ALWNFGVVGMIVIHWRGPLVLQQAYLIFISAQISLMFLKYLPKWTCWLVLAALSVWDIVAVLCPNGPLRLLVEMAHERQQPLFPALLYSTTTVYLVKKHQ
PVENDQQFVGSTITRNEATTQPCTSELVATPDDNTINNDARNNNEISQAPHETDVAGRPNRQELQADLI-DRD--SKGVKLGLGDFVFYSLLIGRATLD-
-GDAVTVVTCYVAILVGMCITVIVLGITRQALPALPISITCGILFYFVSSATISPFLEATAIERFF-
>tr|I1N8G3|I1N8G3_SOYBN Uncharacterized protein OX=3847 OS=Glycine max (Soybean) (Glycine hispida). GN= PE=4 SV=1
---------------------------------------------------------------------------------IIGVMSPVSICMFLVVLLV
YSLSS-PSTIATLVYA--ENPSDTAAQKLEGAVLNAVVFIVFIALATFLLVLLYYYNCTAFLLHYTRFSTFFVLAAMGGSILLSLLERFSVPLDAVTSFL
LLFNFAVVGVLSFAGGLPILLRQCYTVCLGIIVAAWF-TKLPEWTTWTVLVALALYDLVAVLAPGGPLKLLVELESSRNEEL-PALVYE---------AR
PTVNETSRIVVS-RVNSN--NNNNLSSNNDNGENGINDEWERSP--LVGGMRFVPLVEMSGV---GENEEEGERRERGIKFGLGDFVFYSVLVGRAAMY-
--DLMTVYACYLAIISGLGCTLILLSMCRKALPALPISIALGVLFYFLTRLLMEPFIVGTATNLM--
>tr|B9N053|B9N053_POPTR Predicted protein OX=3694 OS=subsp. trichocarpa). GN=POPTRDRAFT_1113048 PE=4 SV=1
---------------------------------------------------------------------------------LVRIITPVSICMFLVVVLV
SILNTDSSSINTIAYN--ETTSDSFWDKFKGALINSLIFVAIITLVTFVLVILFYLRCTHFLKLYMGFSSFLVLGFMGGEIALFLIGDFNIPIDSITFLV
ILFNFASVGVLAFMSKMAIFVTQGYLVVIGVLVAYWF-TLLPEWTTWVLLVALALYDLAAVLLPVGPLRILVELAISRDEDI-PALVYE---------AR
PVTNHDSGSVRR-RVWRE--RSS-VGNGSDENLNSETNSNLTEQ--GQVLEREAPLIDRRTSVQQENSASRENLETGAIKLGLGDFIFYSVLVGRAAMY-
--DFMTVYACYLAIIAGLGVTLMLLAFYQKALPALPVSIALGVLFYFLTRLLLEVFVVQCSLNLV--
>sp|Q9SIK7|PSNB_ARATH Presenilin-like protein At2g29900 OX=3702 OS=Arabidopsis thaliana (Mouse-ear cress). GN= PE=2 SV=1
---------------------------------------------------------------------------------LIAILTPVSICMFTVVLLV
CILNSDPSSFSSAAYS--ESDSDSSWDKFVGALLNSVVFVAAITVATFVLVLLFYLRCVKFLKFYMGFSAFIVLGNLGGEILVLLIDRFRFPIDSITFLI
LLFNFSVVGVFAFMSKFSILITQGYLVWIGVLVAYFF-TLLPEWTTWVLLVALALYDIAAVLLPVGPLRLLVEMAISRDEDI-PALVYE---------AR
PVIRNDSRSVQR-RVWRE--QRSSQNNANRNEVRVVESAEVEEE--HVGSSERVPLIDRRP-----EQAENSELESGAIKLGLGDFIFYSVLVGRAAMY-
--DLMTVYACYLAIIAGLGITLMLLSVYQKALPALPVSIMLGVVFYFLARLLLEVFVVQCSSNLV--
>tr|J3KYR9|J3KYR9_ORYBR Uncharacterized protein OX=4533 OS=Oryza brachyantha. GN= PE=4 SV=1
---------------------------------------------------------------------------------VLAGLSPGSLSLGLVVLLI
SLLAPPSSTAATLVYL--ESPNDSPGQKFVGALLDAAVFVALVAVVTFVLVALYYYRCTGFLKNYMRFSAFFVLFSMGGAIAAAVLRRLGAPLDAATALV
LLFNASAVGVLSVFASVPIVVRQGYMVALAVIVAAWLSR-LPEWTTWIMLVALALYDLVAVLAPRGPLRMLVELASSRDDEL-PALVYESRPMGSVEMQP
VADPGRLEQEDDSSRAVVEMRDLGGSQSSIRDMRNLEREAKQHEEGETAPLPSANNSVPNEEHRQSSS--PDSESTRGIKLGLGDFIFYSVLVGRAAMY-
--DLMTVYACYLAIIAGLGCTLILLSICKHALPALPISIMLGVTFYFLTRLLMEPFVVGSS------
>tr|I1HEG8|I1HEG8_BRADI Uncharacterized protein OX=15368 OS=Brachypodium distachyon (Purple false brome) (Trachynia distachya). GN= PE=4 SV=1
---------------------------------------------------------------------------------VLAVMSPVSICMALVVLLI
SILSPPSSTAATLVYL--ESPSDSPGQKLVGALLDAAVFVALVAVVTFVLVALYYYRCTGFLKNYMRFSAFFVLFSMGGAIAITILRRLDVPLDAPTALL
LLFNASAVGVLSVFASVPILVRQGYMVTLAVIVAAWLSR-LPEWTTWIMLVALAVYDLVAVLAPRGPLRMLVELASSRDDEL-PALIYESRPMWSEEMQL
PADSARSGQQDNLGSAMVEMRDLGGSRSRVHQMGNLEAGAEQPEEEERAPLASANSAVANEEHRQISS--SPPESSKGIKLGLGDFVFYSVLVGRAAMY-
--DLMTVYACYLAIIAGLGCTLILLSICRHALPALPISIMLGVVFYFLTRLLMEPFVVGAS------
>tr|B6TCG9|B6TCG9_MAIZE Uncharacterized protein OX=4577 OS=Zea mays (Maize). GN=ZEAMMB73_866516 PE=2 SV=1
---------------------------------------------------------------------------------VLAVMSPVSICMALVVLLI
SLLSPPSSTAATLVYL--ESPNDSPGQKLLGALLDAAVFVALVAAVTFVLVALYYYRCTGFLKNYMRFSAFFVIFSMGGAIVAAVLRRLGAPLDAATVLL
LLFNGAAVGVLSVFASVPILVRQGYMVALAAIVAAWLSR-LPEWTTWIMLVALALYDLVAVLAPRGPLRMLVELASSRDDEL-PALVYESRPMGSVEMQT
MSDSGQIEQEEYASHASLEMRDLGRGRSSVGEMENLEREAEQPDEEETSPLPSTNTAALDEEHRQSSS--SEPESTRGIKLGLGDFVFYSVLVGRAAMY-
--DLMTVYACYLAIIAGLGCTLILLSICRHALPALPISIMLGVTFYFLTRLLMEPFVVGAS------
>tr|A9S846|A9S846_PHYPA Predicted protein OX=145481 OS=Physcomitrella patens subsp. patens (Moss). GN=PHYPADRAFT_182224 PE=4 SV=1
---------------------------------------------------------------------------------IVGIVTPVSICMFLVVTLV
HILDPREDNIAMMVYN--EQASDSFSEKLGGALLNAIVFVVIVTLVTFMLVALFYYRCTRCLRVYMGISAFTVLAWMGGIVAVQIIKLYSIPIDVITFLI
CTINFASVGVAAVFFCMPIMVTQGYLIVIGMLVAFWFTK-LPEWTTWVLLLAMAAYDVVAVLTPRGPLNLLVELAIERDEDI-PALIYEARPMGSDA---
--ERPRVASRSSSPDTELGESPMSSGNASQRDSQNLIPEANSHMDDDTVPLQTNSPSSPATLGRSEAEFHSEDGLSGAIKLGLGDFVFYSVLVGRAAMY-
--DLMTVYACYLAIVAGLGATLILLAVWQRALPALPISISLGVIFYFLARLVMDPFVLDMS------
>tr|F2EGF7|F2EGF7_HORVD Predicted protein OX=112509 OS=Hordeum vulgare var. distichum (Two-rowed barley). GN= PE=2 SV=1
---------------------------------------------------------------------------------ITRIVGPVSACMLIVVLLV
SLLSSPSST-ASIAAA--AGPGGGGGDDIASAAVTAVTFVAIVTAATFFMALLFYFRCTPCLRAYLGLSAIWILLLLGGQMCLLLLSRLRLPLDVVSCAL
LLPNAAALAVAAISPAVPIALHQAALLAIAVLTAFWFTL-LPEWTTWALLVAMAVYDLGAVLIPGGPLRVLLELAIERNEEI-PALVYGARP-----WRL
WRERGQQSTVEVEVLGRNPLPSSGGNSPNSASQTNLTREARLDIAELRVPLQPDRTSY--DDDDDDDT--DEDASSGAIKLGLGDFIFYSVLVGRAAMY-
--DYMTVYACYLAIIAGLGITLLLLAFYRKALPALPVSISLGVLFYVLTRTLLEAFVMQCS------
>tr|F2CQD9|F2CQD9_HORVD Predicted protein OX=112509 OS=Hordeum vulgare var. distichum (Two-rowed barley). GN= PE=2 SV=1
---------------------------------------------------------------------------------VLAVMSPVSICMALVVLLI
TLLAPPSSTAATLVYL--ESPSDSPAQKLVGALLDAVVFIALVAVVTFVLVALYYYRCTGFLKNYMRFSAFFVLFSMGGAIAVALLRRLDAPLDAPTALL
LLFNASAVGVLSVFASVPILVRQGYMVALAVIVAAWLSR-LPEWTTWIMLLALAVYDLVAVLAPRGPLRMLVELASSRDDEL-PALIYESRPMWSEESQH
HDSAARSGQHDDSAPAMVEMRDLG--------SNQAVTGAERRQEEETAPLASANPTVANEEHTQISS--SPPESSRGIKLGLGDFVFYSVLVGRAAMY-
--DLMTVYACYLAIIAGLGCTLILLSICRHALPALPISIMLGVVFYFLTRLLMEPFVVGAS------
>tr|I1MT67|I1MT67_SOYBN Uncharacterized protein OX=3847 OS=Glycine max (Soybean) (Glycine hispida). GN= PE=4 SV=1
---------------------------------------------------------------------------------IVRIVAPVSICMFLVVILV
SILNTDSSSMVTIAYN--ETTSDSTWDKFLGALLNSLAFVVLVTFATFVLVLLFYFRCTRFLKLYMAFSTFIVLLFLGGEVSIFLIQKFSTPIDCITFFL
VLCNFAVVGVLTVFISMAILVTQGYLVVVGILVAYSFTM-LPEWTTWALLVAMALYDLAAVLLPIGPLRILVELAISRDEEI-PALVYEARPREVAQ---
----RRLQSLNAGPNNAESHSDSGANAGDNWDGANLVENGQETDSDLSAPLGMNVQLG--RGEDTVSI--DNLASSGSIKLGLGDFIFYSVLVGRAAMY-
--DYMTVYACYLAIIAGLGITLMLLAFYQKALPALPVSVGMGVLFYFLTRLLLEVFVVQCS------
>tr|B9SY83|B9SY83_RICCO Putative uncharacterized protein OX=3988 OS=Ricinus communis (Castor bean). GN=RCOM_0845230 PE=4 SV=1
---------------------------------------------------------------------------------IIGVMSPVSICMLLVVLIV
YSLSPSSATAANLVYL--ENPSDSTAQKLEGSLLNALVFVILIAVVTFLLVLLYYYNCTRFLKNYMRFSAFFVLGSMGGSIFLSLIQHFSIPIDSVTCFI
MLFNFTIVGVLSVFGGIPIFFRQGYMVALGIFVAAWFTK-LPEWTTWTVLVALAVYDLVAVLAPGGPLKLLVELAQSRDEEL-PALVYEARPLDLLV-GG
VSDSGSVSNANRNRNESENRVNSEYTSIPVRNVGNVEERSDVAVDEETSPLLRLGSER--EQVRRDAP--EDS-ASRGIKLGLGDFVFYSVLVGRAAMY-
--DLMTVYACYLAIISGLGCTLILLSVCRRALPALPISITLGIIFYFLTRLLMEPFIVGTA------
>tr|Q0V7S4|Q0V7S4_ARATH At1g08700 OX=3702 OS=Arabidopsis thaliana (Mouse-ear cress). GN= PE=2 SV=1
---------------------------------------------------------------------------------IIGVMAPVSICMFLVVLLT
YSLSVTSDSAANLIYI--ENPSDSTTVKLEGSLANAIVFVVLIAAVTFILVLLFYYNFTNFLKHYMRFSAFFVLGTMGGAIFLSIIQHFSIPVDSITCFI
LLFNFTILGTLSVFAGIPIVLRQCYMVVMGIVVAAWFTK-LPEWTTWFILVALALYDLVAVLAPGGPLKLLVELASSRDEEL-PAMVYEARPLRALVGGG
VSDSGSVRNHDVNQLGRENSHNMDYNAIAVRDIDNVDERSESVMDEEMSPLMGWGDNR--EEARGLEE--SDN-SNRGIKLGLGDFIFYSVLVGRAAMY-
--DLMTVYACYLAIISGLGCTLILLSVYNRALPALPISIMLGVVFYFLTRLLMEPFVVGVT------
>tr|F6HMV3|F6HMV3_VITVI Putative uncharacterized protein OX=29760 OS=Vitis vinifera (Grape). GN= PE=4 SV=1
---------------------------------------------------------------------------------IIGVMSPVSVCMLLVVLLV
YTLSSAASTAANLVYL--ESPSDSTTQKLEGALLNALVFIVLIAIVTFVLVLLYYYNFTNFLKNYMRFSAFFVLGTMGGSIFLSVIQHFSVPIDSITCFL
LLFNFTVVGVLSVFSNVPIFVRQVYMVVLGIIVAAWFTK-LPEWTTWVLLVALAVYDLVAVLAPGGPLKLLVELASTRDEEL-PALVYEARPLGLLV-GG
VSESGSVSQDNRNKSDED--------------VGNLAETSEIVVDEEMSPLLEFGGDR--EQTRGEIP--EAS-TSRGIKLGLGDFVFYSVLVGRAAMY-
--DLMTVYACYLAIISGLGCTLILLSVCHRALPALPISITLGVVFYFLTRLLMEPFVVGTS------
>tr|I3RZM0|I3RZM0_MEDTR Uncharacterized protein OX=3880 OS=Medicago truncatula (Barrel medic) (Medicago tribuloides). GN= PE=2 SV=1
---------------------------------------------------------------------------------IIGVMSPVSICMFLVVLLV
YTLSTTPETAANLVYA--ENPSDTTAQKLEGALLNAVVFIILIAIVTFLLVLLYYYNCTAFLRNYVRFSAFFVLATMGGSIFINLIERFSIPLDSITFFI
FLFNFTIVGVLSVFAEIPIIVRQCYMVCLGIFVAAWFTK-LPEWTTWTLLVALALYDLVAVLAPGGPLKLLVELASSRNEEL-PALIYEARPFGLFV-AG
VSEAQPTPIVNMNERDNDIHIEGGGGDDSVAGVEDFRER-----EEERSPLM--GNER--REPREREE------AERGIKLGLGDFVFYSVLVGRAAMY-
--DLMTVYACYLAIISGLGCTLILLSVCRHALPALPISIALGVLFYFLTRLLMEPFIVGTA------
>tr|K3XBK3|K3XBK3_PYTUL Uncharacterized protein OX=65071 OS=Pythium ultimum. GN= PE=4 SV=1
-----------------------------------------------------------------------------------AVVWPVTITMLLASFVS
SNVDPSTAADAYLIYGPDSDAEASDGTKFEEAMINALAIVSFFLIATFVIVCCYKFNFNRMLIGYMMFSSMMLLGLLGGNIVTIALAQTGCIVDIATMFF
ALYNFAVVGVISIFYQAPKWIGQVYLVLTSVIMAWQL-GQFPEWSTWALVIVLAFYDLCAVLTPCGPLKWLVNLVQQEGRPL-PGLLYEAEV-----RRE
PSSSSSSPVTAQQYYQYD-PEAPREANRPNNAAPPPLTPHEKVVRERLVKAQHNPAVIARVRDLHEKYIADDLEEENTIKLGLGDFVFYSVLVSRAAKF-
--DFSAMVGCLVTVLMGLGGTLFLLGVYKKALPALPISILLAVTIYFWIHGVFVEYANSA-------
>tr|F0W9T2|F0W9T2_9STRA Presenilinlike protein putative OX=890382 OS=Albugo laibachii Nc14. GN= PE=4 SV=1
-----------------------------------------------------------------------------------AVVAPVTLTMILASLFS
IEIDPTTAANTYLVYKPQKASTETNGMKIEEALINAVVIVSFFLVATFGIVFCYKFRCTNILIVYMMASSVMLLGFLGGHLLLLTLTQVGIMVDAPSFLF
LGYNFAVAGVLSIFYQLSIKITQSYLICTSVIMAWQF-GQLPEWTTWALVTMLAFYDLCAVLTPYGPLRCLVNLVQEQGRPL-PGLLYEADV-----GHG
TDGNANSPIAKRSYYQCE-SDHTMQRERSDDA--------EERMKTRLVSKRVDPASLQNVRELTKRYLVEE-EESNTIKLGLGDFVFYSVLVSRAARY-
--DFCAMIGCISAILVGLGGTLYLLGLYKKALPALPISILLSVSVYFWVRTAYIPYVRSL-------
>tr|G4ZQQ2|G4ZQQ2_PHYSP Putative uncharacterized protein OX=1094619 OS=(Phytophthora megasperma f. sp. glycines). GN=PHYSODRAFT_316247 PE=4 SV=1
-----------------------------------------------------------------------------------AVVWPVAVTMLLASFVS
LNVDRASAAEAYLVYGPDKDKGASTGTKVENALVNALAIVSFFLVATFVI----------MLIGYMMFSSAMLLGMLGGNMLVIVIAKMEIPVDVFTLLF
AMYNFSVVGVLSIFYQMPMWLTQTYLVATSVIMAWQL-GQFPEWSTWALVIVLAFYDLCAVLTPCGPLKWLVNLVQQEGRPL-PGLLYEAEI-----RRD
HSGNAAPPVRENVYYQCE-TEIPSSREAPASTEPTVLTPRQAQMRARLIETKHNPEAISRVHDLYQKYITDEGDVDETIKLGLGDFVFYSVLVSRAAKY-
--DFSAMVGCLVSVLMGLGGTLFLLGIYQKALPALPISILLAVTMYFWLRVVFVDFASSA-------
>tr|D0MT31|D0MT31_PHYIT Presenilin-like protein OX=403677 OS=Phytophthora infestans (strain T30-4) (Potato late blight fungus). GN=PITG_00176 PE=4 SV=1
-----------------------------------------------------------------------------------AVVWPVAVTMLLASFVS
LNVDPASAAEAYLIYGPEQDKGASTGTKMTDALVNALAIVSFFLVATFVI----------ILIGYMMFSSAMLLGMLGGNMLVIVIAKIEIPVDVLTLLF
VMFNFSVVGVLSIFYQTPMWLTQTYLVATSVIMAWQL-GQFPEWSTWALVIVLAFYDLCAVLTPCGPLKWLVNLVQQEGRPL-PGLLYEAEI-----RRN
HSGHTAQPVHEYVYYQCE-SEIPSPRDVPEAPMTSTLTPRQSQLRARLVDSKHNPSAIARVHDLYQKYVTEQGEVDETIKLGLGDFVFYSVLVSRAAKY-
--DFSAMIGCLVSVLMGLGGTLFLLGIYQKALPALPISILLAVMMFFWLRVVFVDFASSA-------
>sp|Q54ET2|PSNA_DICDI Presenilin-A OX=44689 OS=Dictyostelium discoideum (Slime mold). GN= PE=3 SV=1
-------------------------------------------------------------------------ELVDYSEMIVSILYPVCITMVIVVLAI
RAISSSTSKNSQEISNDNSDSSSGADKMVFDSVVNSLIFLAVIILSTTIMVVLYKFKLMKALYAWLMGTSILLLGVFGGFLFLILLAYLNLGLDYVTFVI
VVWNFSVGGIVCIFWYSPKLLNQGYLISISVLMAL-FFSRLPDWTTWGILSIVSIYDIFAVLCPGGPLRILIETAQKRNENI-PAMIYNASI--YIGMIY
NEDNLENNNNNNNNNTEDGNNNNNKNKNNNNNNNRIENENGENENGSITPPPTIKEINRSSDEIVSNAESSIDTSKQSIRLGLGDFVFYSVLIGKAASY-
--QITTVFTVFIAIITGLFLTLILLAVFRRALPALPMSIIFGIIVFFLTFKILIQYIYFLGENQIFV
>tr|F4PRZ5|F4PRZ5_DICFS Presenilin family protein OX=1054147 OS=Dictyostelium fasciculatum (strain SH3) (Slime mold). GN= PE=4 SV=1
-------------------------------------------------------------------------SIKEYSKAMVSIALPVSISMAIVISAV
RLSEEARNFKSVLIQYDVR-EDPATQTLVWGTIINSLILVGIIFLSSVIMFALYYFKFMKALYGWLMATSILLLGVFGGFLFILLMTYANVGLDYFTFSF
IVWNFSAGGMVCLFWFCPQYLTRAYLVSISSLMAI-FISRMPEWSTWSILTIVSLYDIFTVLSPGGPLKKLIDLAKERGDEI-PALVYNGSV--SIGMAS
SKNNTTPTTKTTTNDSDTSSNSSSSSSSSSSSSSNIQKSTSSSTGLSTEPS---------------------DPESTKIQLGLGDLVFYSVLLGRAALY-
--DLGTIFACFVAILTGLFITLILLIVYKKAIPALPISIFIGILFFFSTSKLICPFLVFLGENQVFI
>tr|A8IAG6|A8IAG6_CHLRE Presenilin protease OX=3055 OS=Chlamydomonas reinhardtii (Chlamydomonas smithii). GN= PE=4 SV=1
---------------------------------------------------------------------------------VTGIVAPVSLCMAVTVLLV
RLLNPEGVSSSNLIASIAEQASDSSGKKFGGALLNALIFVAVVAGMTVVLFLLFKYKCYKFIFAYMGFAVFNIFFFITGALFIQVMQVIDLHIDAFSLAY
GLFNFSIVGTLGLFMPIPLLSKQVYLIWVGIIVAYIF-TFIPEWTAWVILCFMALYDIVAVLVPGGPLKALVELAIERQQEL-PALIYEARPPYVRGWG-
NRGQRGEGEGPDGPGGPAGAVPAPPNVVPSGRRGACSGRWTHTPVAARNTLDGELPASEPPPQLPHHRDGGADGEDDSIKLGLGDFIFYSMLVGRAAMY-
--DFMTVFAAYLAIIAGLGLTLLCLAVFQKALPALPFSIALGVAFYFLTRLTLEPFLIPLATNLAF-
>tr|E1ZBN0|E1ZBN0_CHLVA Putative uncharacterized protein OX=554065 OS=Chlorella variabilis (Green alga). GN=CHLNCDRAFT_144542 PE=4 SV=1
---------------------------------------------------------------------------------VTGIVAPVSICMAITLALV
RILNPEGDSDSNFLASAYEQEGDSPGQKLSGAVVNALIFVGVVAAMTFALVLLFKHGYVRVIYAYMGFAGFSIFFVLTGLISIQLLQKAAIHTDFITFTY
ILLNFAAVGSLTFFFPAPLLMKQCYLIVTGVVTAYVF-TWIPPWTTWTLLVAMAVYDVVAVLVPGGPLKMLVELAQEREEAL-PALVYEARP--VRRQP-
SQPRSQEGEGPEG-GSAAGDTELPPRPAPPSGRGIIHGE-----------VEVEVEAEADTQALQPGQAADEDDEDDSIKLGLGDFIFYSICLSRAAFS-
--GWAAAFATYLAILAGLGCTLLWLAVARRALPALPISIALAVACFVLAKAVMEAVVLPASLALVY-
>tr|I0YVD1|I0YVD1_9CHLO Presenilin-domain-containing protein OX=574566 OS=Coccomyxa subellipsoidea C-169. GN= PE=4 SV=1
---------------------------------------------------------------------------------VAGIVAPVSICMALTVFLV
RVLNPNGDSDTSLIASAYEKADDSTGTKLAGSVINALIFVVIVGLMTFVLVLLFKYGCVRFIYGYMAFAGFSIFFFLTGVIALQLIEKASLRLDAFSFLY
ILFNFAVVGVGSFFWPAPVLLKQGYLVVTGVVTAYMF-TFIPEWTTWTLLIAMALYDLYAVLTPGGPLKVLVELAIERDQDI-PALIYE---STVRSLA-
GQSQREQ-DGAATPGSGDAVLPL-------NGDGV--GTWQLTSLAGGVSHRGKMMGAGGSVPLPPQRESEDD--EDSIKLGLGDFIFYSVLVGRAAMY-
--DMLTVFAAYLAIIAGLGMTLLLLAVAQKALPALPISIALGVSFYFTTRLLLEPFILPLSTNLLM-
>tr|D3B5F5|D3B5F5_POLPA Presenilin family protein OX=13642 OS=Polysphondylium pallidum (Cellular slime mold). GN=PPL_03893 PE=4 SV=1
--------------------------------------------------------------------ENEELEIDYSD-QMVSIAIPVFFTMVVVTAVI
RAISVP---DNQDIPAGFKYDTDNIQQVFLNTLINSLIFLGVVVLSTVIMVILYKFKFMKALYGWLMATSILLLGVFGGFLFILILTYVNIALDYLTFVF
VVWNFSAGGIVCIFWFCPKYLNQAYLICLSAFLAL-FLARFPSWTTWAILVLVSIYDIFAVLCPGGPLQQLIETARKRGESI-PALIYNASV--FIGMAE
SESIE-----MNTTTTATQQQNNTNNSQPFPTPTSIPINLP-SQSEMIEPNSESMSTGVSTSELSESTDSVTLEKGRGIKLGLGDFVFYSVLVGRAAYK-
--EIILVFICFVAILTGLFITLLLLAVYKRALPALPIKMKFNKLLLVS-------------------
>tr|G7L2M4|G7L2M4_MEDTR Presenilin OX=3880 OS=Medicago truncatula (Barrel medic) (Medicago tribuloides). GN=MTR_7g087200, MTR_7g087280 PE=4 SV=1
--------------------------------------------------------------------------------EIIGVMSPVSICMFLVVLLV
YTLSTTSSTAANLVYA--ENPSDTTAQKLEGALLNAVVFIILIAIVTFLLVLLYYYNCTAFLRNYVRFSAFFVLATMGGSIFINLIERFSIPLDSITFFI
FLFNFTIVGVLSVFAEIPIIVRQCYMVCLGIFVAAWFTK-LPEWTTWTLLVALALYDLVAVLAPGGPLKLLVELASSRNEEL-PALIYEARPAFGLF-VA
GVSEAQPTQSSSIEQELQ-VVPIVNMNERDNDGGGDDVAFRNDEGERVGNNGNREEERSPLEVMGNERPREREEAERGIKLGLGDFVFYSVLVGRAAMY-
--DLMTVYACYLAIISGLGCTLILLSVCRHALPALPISIALGVLFYFLTRLLMEPFIVGTA------
>tr|C7J054|C7J054_ORYSJ Os03g0603700 protein OX=39947 OS=Oryza sativa subsp. japonica (Rice). GN= PE=4 SV=1
---------------------------------------------------------------------------------ITRIVTPVSTCMLLVVLLV
SLLSSPSSP------SPFTAAAGGGGDDITTALITAVTFVVAVTAATFLLAFLFYLRCTPCLRAYLGFSSLSVLLLLGGHVALLLLSRLRLPLDAASFAL
LLPNAAALALAALSASVPIALHQAALVAIAVLTAFWF-TLLPEWTTWALLVAMAVYDLAAVLLPGGPLRLLLELAIERNEEI-PALVYEARPVWRLWR--
--ERTQSGAELDANSTVEGTGASSAGNSAIRSRVGLAGDARNLRLGTVEVLPASPEISVSVPEMRVPRTRDEEDDSGAIKLGLGDFIFYSVLVGRAAMY-
--DYMTVYACYLAIIAGLGITLLLLAFYRKALPALPVSIALGVVFYVLTRTLLETFVMQCS------
>tr|K4A9R1|K4A9R1_SETIT Uncharacterized protein OX=4555 OS=Setaria italica (Foxtail millet) (Panicum italicum). GN= PE=4 SV=1
---------------------------------------------------------------------------------ITRIVYPVSACMLLVVLLV
SLLSSPSSP------SPLTAATGGGGDDIPTALVTALTFVVAVTAATFLLALLFYLRCTPCLRAYLGFSALAVLFVLGGQVALLLLSRLRFPLDAVSFAL
LLPNAAALALAALAASVPIALHQAALVAVAVLTAFWF-TLLPEWTTWALLVAMAIYDLAAVLLPGGPLRVLLELAIERNEEI-PALVYEARPVWRLWR--
--EGRQPGADLDASSTVDGRDANSGNSSAPQVATISAGNVNNSRPREAGEVSALREHRVAVAEMRVPRSGEEEEDSGAIKLGLGDFIFYSVLVGRAAMY-
--DYMTVYACYLAIIAGLGITLLLLAFFRKALPALPVSIALGVVFYVLTRTLLEEFVVQCS------
>tr|F2DS25|F2DS25_HORVD Predicted protein OX=112509 OS=Hordeum vulgare var. distichum (Two-rowed barley). GN= PE=2 SV=1
---------------------------------------------------------------------------------ITRIVGPVSACMLIVVLLV
SLLSSPSSP------SPLTAAAGGGGDDIASAAVTAVTFVAIVTAATFFMALLFYFRCTPCLRAYLGLSAIWILLLLGGQMCLLLLSRLRLPLDVVSCAL
LLPNAAALAVAAISASVPIALHQAALLAIAVLTAFWF-TLLPEWTTWALLVAMAVYDLGAVLIPGGPLRVLLELAIERNEEI-PALVYGARPVWRLWR--
--ERGQQGGDLDPSSTVEGRLPSSGGNSASQAQTNLTGAVSNSRLRSAREALALPETRLDIAELRVPRTDDDDTDSGAIKLGLGDFIFYSVLVGRAAMY-
--DYMTVYACYLAIIAGLGITLLLLAFYRKALPALPVSISLGVLFYVLTRTLLEAFVMQCS------
>tr|K3WL66|K3WL66_PYTUL Uncharacterized protein OX=65071 OS=Pythium ultimum. GN= PE=4 SV=1
------------------------------------------------------------------------SDLMHGINSFWAIVFPVCVTMI--IASL
AVVNYRNSMQTYLVYGS--SDQDSGAQQLGMSLVNAVVIIGAIAVLTFGMALLYKYNCMKFLGGYIMFASTAILSFVGGQLVDSINDQLGWPVDWITFLF
VMINFGFVGVISIFYKGPKFVQNGYLVLVSVILAWEFS-MWPMWTTITFCFMFAIYDLCAVLTPCGPLKCLINLIQEKQAPL-PGLLYEADVRDGVTNAA
AAPRARKSPRAAATASASASGNSSSSSSAASSDATVTENFNRPRNSDFSPEDVWPCAVQARQDAKRRAAEEEDDDDKTIKLGLGDFIFYSVLVGRAAIY-
--DFSTFAATFICIVMGLGGTLFLLAVLHKALPALPISIFLATFFYFWTYYLFVDFCDF--------
>tr|H3GE34|H3GE34_PHYRM Uncharacterized protein OX=164328 OS=Phytophthora ramorum (Sudden oak death agent). GN= PE=4 SV=1
------------------------------------------------------------------------DDLMHGINSFWAIVFPVCVTMI--IASL
VVVNYRSSMSTYLVYGD--SGADSGGSGIGESLVNALVIIGAIAVLTFGMALLYKYNCMKFLSGYIMFASTAILSFVGGQLVDEINDQFGWAVDWPSFLF
VMINFGFVGVISIFYKGPKFVQNGYLVMVSVILAWEFS-MWPEWTTITFCVMFACYDLCAVLTPCGPLKYLIGLIQEKQAPL-PGLLYEADVRDGVSHQQ
QQRQQQEQRRKNTPTDRQSSSNSNHNASPSTDRESSPIPLGRPRNSNFSPEDTWPCPVQARRDRRQRQQEEEDEDDKTIKLGLGDFIFYSVLVGRAAIK-
--DFSTFAVTFVCIVMGLGGTLFLLAVLHKALPALPISIFLATIFYFLTEYIFIDFCSF--------
>tr|G4Z6U7|G4Z6U7_PHYSP Putative uncharacterized protein OX=1094619 OS=(Phytophthora megasperma f. sp. glycines). GN=PHYSODRAFT_350670 PE=4 SV=1
--------------------------------------------------------------------------LMHGINSFWAIVFPVCVTMIV--ASL
VVVNYRSSMSTYLVYGNSGSDSSSGGAGIGESLVNALVIIGAIAVLTFGMALLYKYNCMKFLSGYIMFASTAILSFVGGQLVDEIVDQFGWAVDWPSFLF
VMINFGFVGVISIFYKGPKFVQNGYLVMVSVILAWEFS-MWPEWTTITFCVMFACYDLCAVLTPCGPLKYLIGLIQEKQAPL-PGLLYEADVRDGVSHDH
QQPQEQPRRPKNATDTAPSSSTTSQSSSNSNQNATFSDTWKAPQVAEFFAMPCPVQARRERRQRQR---EEEDEDDKTIKLGLGDFIFYSVLVGRAAIK-
--DFSTFAVTFVCIVMGLGGTLFLLAVLHKALPALPISIFLATIFYFLTEYIFIDFCS---------
>tr|F0VZ14|F0VZ14_9STRA Presenilinlike protein putative OX=890382 OS=Albugo laibachii Nc14. GN= PE=4 SV=1
-------------------------------------------------------------------------DLMHGINSFWAIILPITITI--TIASI
VVVNFRNEKKSYLVYGDAEQNS---GSSVGRSLINAVVLISAIAILTFGMVLLYKYNCIKFLAGYIMFAVVSILSFVG----GQLMDQIGWIVDWPSFTF
IMVNLGLVGVVAIFYQGPKLIQGAYLVLSSVILAWQFS-MWPEWTTWIFCFSFACYDLCAVLTPCGPLKCLINLIQDKQTPL-PGLLYEADVSDRVRESL
TEPPVDDGQSRNPTRSHS--HSSSQAKRPTVEESDFSPYWKVQVAEKESQDRLWPVERAEAKK-RSENEMLDDQEANTIKLGLGDFIFYSVLVGRAAIY-
--DFSTFVVCFLCVLLGLGGTLFLLSVLHKALPALPISIFLAIMVYFWTRYVFVDYGDFLLMH----
>tr|G2J6Q7|G2J6Q7_CAEBR Protein CBR-SPE-4 OX=6238 OS=Caenorhabditis briggsae. GN= PE=4 SV=1
--------------------------------------------------------------------------------------FSVVVNMSLTLAI-
-WIGIYHMVNSELSKMYFLDDSWTTGNPALDGLINGLVLGCVSFVM--LAFVLYDFRR--IVKSWLTFSCLLILFGVSGQTIYDLFDQNDENQFILTVAL
TVIVYGCLGIYAFLANGSLLLHQFFVVSNCSLIAVFYLRAFPKHTTWFVLWTVLFWDLFAVLAPMGPLKKVQEKASDYSNNILKILMFAAEDSAGMDMAQ
DSQNDERKLRKDVK------ELIQLYSKQDEKDDEFLQKIRQRRNAIHSPNETAAECAPEEQNEFDQTVTAADNDGETVRLGFGDFVFYSLLIGQAATG-
-GCPISVGFAAFGILFGLIATLTVLSSEESTTPALPLPVICGTFCYFVSRFLVDEFWV---------
>tr|H2VWC4|H2VWC4_CAEJA Uncharacterized protein OX=281687 OS=Caenorhabditis japonica. GN= PE=4 SV=1
--------------------------------------------------------------------------------------FSVIVNMLLTLSV-
-WIGVYGMVNSELSRLYFLDTASTTGNPVLDGAINGVVLGIVSFVM--LGFVLYDFQN--LVKTWLIFSCLLILFGVSGQTFYDLFDQETENGRNLTLVL
TILVYGLAGIVAFLANGSLLLHQCFVVSNCSLIAVFYLRAFPRHTTWFVLFIVLFWDLFAVLTPMGPLKRVQEKASDYSNNILKFLMFAADDSAGADRAE
EVNEGDGTIRRGVK------QLIAMYSKQEAQDEEFAQKIRQRRSAWQSPSETAEECDMETANKQGDNLTAADNDGETVRLGFGDFVFYSLLIGQAAAS-
-GCPIAVVFAAAGILFGLLVTLTVLSTEESTTPALPVPVLCGTFCYFTSKFVWENLIM---------
>tr|G0NCU3|G0NCU3_CAEBE Putative uncharacterized protein OX=135651 OS=Caenorhabditis brenneri (Nematode worm). GN=CAEBREN_32611 PE=4 SV=1
--------------------------------------------------------------------------------------FSVIANMSLTLSI-
-WIGIYRMVNSELSKMYFLDDSWTTGSPTLDGLINGLVLGGVSFIM--LAFVLYDFRR--IVKLWLTFSCILILFGVSGQTIYDLFDQNDENGFLMTVFC
TVIVYGCLGIYAFLANGSLLLHQFFVVSNCSLISVFYLRAFPRYTTWFVLWTVLFWDLFAVLAPMGPLKKVQEKASDYSNNILKFLMFAAENSAGMDMLE
GSENEERKIRQNVS------QLIQMYSKKEEKDDEFLQKIRQRRTAIHSPDETADECAPEEQEVVPEQVTAADNDGETVRLGFGDFVFYSLLIGQAATG-
-GCPVAVALAAFGILFGLIVTLTVLSNDESTTPALPVPVICGTFCYFISKLVMDQFYY---------
>sp|Q01608|SPE4_CAEEL Presenilin spe-4 OX=6239 OS=Caenorhabditis elegans. GN= PE=1 SV=1
--------------------------------------------------------------------------------------FSVIANMSLTLSI-
-WIGVYNMVNSELSKTYFLDPSQTTGNLLLDGFINGLVLGCVSFIM--LAFVLFDFRR--IVKAWLTLSCLLILFGVSAQTLHDMFDQDDNNQYYMTIVL
IVVVYGFGGIYAFFSNSSLILHQIFVVTNCSLISVFYLRVFPSKTTWFVLWIVLFWDLFAVLAPMGPLKKVQEKASDYSKCVLNLIMFSANETAGSNQEE
TNEGEESTIRRTVK------QTIEYYTKREAQDDEFYQKIRQRRAAIHSPDETAEECDQKES-LPNNPATAADNDGEVLRLGFGDFVFYSLLIGQAAAS-
-GCPFAVISAALGILFGLVVTLTVFSTEESTTPALPLPVICGTFCYFSSMFFWEQLYG---------
>tr|E3N426|E3N426_CAERE CRE-SPE-4 protein OX=31234 OS=Caenorhabditis remanei (Caenorhabditis vulgaris). GN= PE=4 SV=1
--------------------------------------------------------------------------------------FSVIVNMSLTLSI-
-WIGIYQMVNSELSKLYFLDDSRTTGNTTLDGLINGLVLGCVSFVM--LAFVLYDFQR--VVKAWLTLSCMLILFGVSGQTLYDLFDQNDENQYILTVAL
TVIIYGVLGIYAFFANGSLALHQFFVISNCSLISVFYLRAFPRYTTWFVLWMVLFWDLFAVLAPMGPLKKVQEKASDYSNNILKFLMFAAEDTAGIDATE
DSSNDERKLRKDVK------QLIELYSKKEAQDDEFLRKIRQRRTAITSPDETAEEVAPEEQEEFDQPVTAADNDGETVRLGFGDFVFYSLLIGQTATG-
-GSALAVACSALGILFGLVATLTVFSSGESTTPALPLPVICGTFCYFISKFVVDQVYG---------
>tr|K0T4V4|K0T4V4_THAOC Uncharacterized protein OX=159749 OS=Thalassiosira oceanica (Marine diatom). GN=THAOC_04613 PE=4 SV=1
------------------------------------------------------------------------------SQQVVFLDPPVCLTMILAALA-
--VHYVN-----------TEQTREAGEKALARSYQVFD-ISEQSAATS-----IGLGCMKCLIGYMVFASTLLGFLGSQMFMVA-IQKYRIPLDWLTFVF
VMYNFAITGVIAVFYKGPTYVNQGYLVLTSVIVAW-QLSYFNEWMSWTLLIALALYDLCAVLTPCGPLKALVKEMSKDNAPSMPGLLYEAGLPDNAVRAE
DDENNRRRTSQNSGAEAASSGERPSGVAPAKKDGRFKPKGRTQGNCPESPRHSTPDPRRETGELKRTLSGGEDDIDNNIKLGLGDFIFYSVLVSKATERG
---FAPFVACFLCILQGLGGTLVLLAVYHKALPALPSSIFLSVAMFVLAVFVITPWIED--------
>tr|E1G929|E1G929_LOALO Presenilin spe-4 OX=7209 OS=Loa loa (Eye worm) (Filaria loa). GN= PE=4 SV=1
------------------------------------------------------------------------------KKMVERLLIPVTLNILLT--LI
VWIGVYHTTDSNVYYMLDPGHNRTTGNEIVDGMVNGILMLAVIS-FALLAMALYDYKC--LVQMWLYMSCVLIIFGVFASFLVDLFKAFGLQTAPIFTAL
IVITYGTVGILVFFKKTPLYMHQFYVICNCSLVSVFYLRMFPTHTAWFVLVCIIIWDTFAVLAPVGPLRRINEKAHEYSDQVLRFLMF--------TAED
KNDEPYEETNKSFIKRKQERHERRSKTKL--D-S--EAENEHLRQRKKSDTQVESKFRAASDEQRNDGTTDALNDGSSVRLGMGDFVFYSLMVGKAAAT-
-HNAMCVIGSMVGILVGLIVTLTILSNDDETTPALPVSITIALLLHFGIYLFVEPFYSQIVITQ---