>seq_1
MKKILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTIFEEEKPDLIILDLMLPELDGLEVAKEIRKTSHVPIIMLSAKDSEFDKVIGLEIGADDYVT
KPFSNRELLARVKAHLRRTETIETAVAEENASSGTQELTIGNLQILPDAFVAKKHGQEVELTHREFELLHHLANHMGQVMTREHLLEIVWGYDYFGDVRT
VDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSYDTRDIIGNLSTFELAILILLVFVAFYFIHLAVRDYRNARIIRMMSHKIRDLINGRYTDIIDEKAD
IELMELSDQLNDLSDVFRLTHENLAQEKNRLASILAYMSDGVLATDRSGKIIMINETARKQLNLSKEEALKKNITDLLEGDTSYTYRDLVSKTPVVTVNS
RNDMGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALKEDIAPSFIKVSLDETNRMMRMISDL
LNLSRIDNQVTQLAVEMTNFTAFITSILNRFDLVKNQHTGTGKVYEIVRDYPITSVWLEIDNDKMTQVIENILNNAIKYSPDGGKITVRMKTTDTQLIIS
ISDQGLGIPKTDLPLIFDRFYRVDKARSRAQGGTGLGLAIAKEIIKQHHGFIWAKSDYGKGSTFTIVLPYEKDAAIYEEWEEDVD
>tr|K9ZK57|K9ZK57_ANACY Multi-component transcriptional regulator, winged helix family OX=272123 OS=Anabaena cylindrica PCC 7122. GN=Anacy_4264 PE=4 SV=1
--KILVVEDDELNAYALTAVLTDQNYAVEVATDGDAAWDLIETYDYDLILLDVLLPKLDGISLCRQIRSSRQVPILLLTGCDRSHEKATGLDAGADDYVV
KPFDQQELVARVRALLRRGSATLAP-----------ILEWGNLQLDPSSCEVTYGQNLISLTPKEYALLELFLRNQRRVFSCGMILEHLWSYEDTPGEEA
VRTHIKGLRMKLRNANVPHDLIETVYGIGYRLKPLKESTLAGSLGTFALPLGSKLLILAILFLIEPELVTRIINRLERVRRQTHNIQDLAYGIVALHKIQ
DELAELITANYNLQSERQRTQEALIISQTRFEGILSIADDAIISIDSNQCITLFNQGAEKIFGYSAEEVLGKQ-LDLLLPMRFSEQRHHVTDFGKSPSPA
RRIFGRGTEFPAEASISKLNVGLESVYTVILRDITERRQIERMKDEFVSVVSHELRTPLTSIHGSLGMLASGLLPTNQGKRLLQIATDSTERLVRLINDI
LDIERIESGKVKMERENCNLDELINSALNIMQPLAN-----KAGVILSIS--SLSVQLWADPDRIVQILTNLLSNAIKFSTSGATVWLTAKQQENEVLLT
VKDTGRGIPSDKLDSIFERFQQVDSSDSRNHEGTGLGLAISKSIIQQHGGEIWVESVLNEGSSFYLTLPI---------------
>tr|G6FPU0|G6FPU0_9CYAN Multi-component transcriptional regulator, winged helix family OX=741277 OS=Fischerella sp. JSC-11. GN=FJSC11DRAFT_0870 PE=4 SV=1
--KILIVEDDELVAHVLAAVLTNYNYAVEEAFNGQAAWDLIQTFDYDLILLDVILPEIDGITLCRKIRAHLQMPILLLTGCDSSHEKAIGLDAGADDYLV
KPFDEEELVARIRALLRRGGAISQP-----------VLEWGNLRLDPTSCEVTYAGELLPLTPKEYALLELFLRNSRRVFSCGMILEHLWSYDDIPGEEA
VRTHIKGLRHKLKAVGAPGDLIETVYGIGYRLKP-RRETLAGSLATFSFAVGSQLLIGAILFLVGPELVTRIVNRLERFSREIYQGGNTQAETQELRQAK
EELAELTRINQQLQSERQRTQEELRNSQAMFAGIVSIADDAIISIDGSQKITLFNQGAEKIFGYTSQEVLGQP-LDILIPSQYIQARQYVADFGRSTKVA
RRIYGRGSEFPAEASISKLQLGQEIVYTVYLQDVSDRKQVERMKDEFVSVVSHELRTPLTSIHGSLGMLASGLIKPDQGKRLLQIAVDSTDRLVRLINDI
LDIERIESGKVKMEKQTCNVADLIAQAINVMQPLAD-----KAKVTLSVS--SLSQQLWADPDRIVQTLTNLLSNAIKFSTAGSTVWLSAELPNYHILFT
VRDTGRGIPSDKLESIFERFQQVDSSDSRNHEGTGLGLAICKSIVQQHGGEIWVDSQLNEGSTFYFTLPV---------------
>tr|K9TZ23|K9TZ23_9CYAN Multi-component transcriptional regulator, winged helix family OX=251229 OS=Chroococcidiopsis thermalis PCC 7203. GN=Chro_2617 PE=4 SV=1
--KILVVEDDELVAHALTAVLTNHNYAVEVAVDGLAAWDLVQAFDYDLIVLDVVIPKLDGISLCRQIRAKLSMPILLLTGRDSSHEKAIGLDAGADDYLI
KPFDEEELVARVRALLRRSGLVSPP-----------VLKWGDLQLDPSSCEATYRQKHLSLTPKEYALLELFLRNSRRVFSCGTILEHLWSYEDLPSEEA
VRTHIKGLRQKLKAAGANSDLLETVYGIGYRLKPLKRETLAGSLGTFGLAQGSKLLILAILFLVGSELVTRIVNRLERIKHQVRATNNVESENR------
------CKLNEQLQSERQRTQAALQNSQALFAGIVAIADDAIISIDSNQRITLFNSGAERIFGYSAAEAIGQP-LDLLLPMRFATARQHVDEFGQSPNSA
RRIYGCGTEFPAEASISKLNLGGKTVYTVYLHDVSDRKQIERMKDEFISVVSHELRTPLTSIHGSLGMLASGLLQPDQGQRLLQIATDSTERLVRLINDI
LDIERIESGKVKMEKESCDVTELITEAVNVMQPLAD-----KAGITLSVS--SLPIQVWADPDRIVQTLTNLLSNAIKFSPSGSTVWLSVELLTPHITFQ
VKDTGRGIPADKLDSIFERFQQVDSTDSRKHDGTGLGLAICRSIVQQHDGRIWVESVLGEGSTFYFTLPI---------------
>tr|K9PQ80|K9PQ80_9CYAN Multi-component transcriptional regulator, winged helix family OX=99598 OS=Calothrix sp. PCC 7507. GN=Cal7507_4921 PE=4 SV=1
--KILVVEDDELLAATLTAILTNHNYAVEVAIDGDAAWNLIEIYDYDLILLDVILPKLDGVSLCRQIRSSMQMPVLLLTGRDSSHEKAIGLDAGADDYVV
KPFDAEELVARVRALLRRGASTSQP-----------VLEWGDLRLDPSSCEVTYAQDLLSLTPKEYALLELFLRNSHRVFSCGMILAHLWSYDDTPTEEA
VRTHIKGLRQKLKAVGVASDLIETVYGIGYRLKPQEARTLAGSLGTFGLAIGSELLILTILFLVGPELVTRMINRLERVKRQAHNQRDRAFAEVALQKAN
NELAELVGLNRKLRSQRQRIQEELRISQAKFARILDIADDAIISIDSHQCITLFNQGAEKIFGYSAEEVIGQR-LDLLLPPRFAQSRHHVTDFGQSPSLA
RRIFGCGTEFPAEASISKLNMGNEIFYTVILRDVTERKQIERMKDEFVSVVSHELRTPLTSIHGSLGMLASGLLNADPGKRLLQIATDSSDRLVRLINDI
LDIERIESGRVKMARETCNLADLIKSAVNVIQPLAD-----KAGVQISIA--SLSMQLWADQDRIVQTLTNLLSNAIKFSAAESTIWLTTQKQGNEVLLA
VKDTGRGIPSDKLDSIFERFQQVDSSDARNHDGTGLGLAICQSIVQQHGGHIWVESILGEGSTFYFTLPI---------------
>tr|D4TMU3|D4TMU3_9NOST Multi-component Transcriptional regulator, Winged helix family OX=533247 OS=Raphidiopsis brookii D9. GN=CRD_00257 PE=4 SV=1
--KILVVEDDALIACTLSNFLTYQNYAVEVANDGKTAWDLVETYEYDLILLDIVLPKLDGISLCKKIRSSRRVPILLLTGRDSSHDKAIGLDAGADDYVV
KPCDEEELVARVRALLRRGGVTSQP-----------VLEWGGLRLDPSSCEVTYQQDQLSLTPKEYALLELLMRNNRRVFSCGMILDHLWSYEDTPGEDA
VRTHIKGLRMKLKAAGAPHDLVETVYGIGYRLKP-QEDTLAGSLGTFGLPYASEL-TLEILFLIISELVNRILNRLERVRK-----K-------ALRKTK
DELSELINVNHQLQSQQKRTQDALRISENRFEAILSIADDAIISIDNSQGITLFNQGAEKIFGYTAEEVLGKK-LDLLLPTRFAQERNHVSTFGKSSAHA
RRIFGCGSEFPAEASISKLDLGPESVYTVILRDITERKQVEKMKDEFVSVVSHELRTPLTSIHGSLGMLTSGLLSTTQGKRLLQIATDSTERLVRLINDI
LDIERIESGKVKMERENCDLRDLINSAINIMQALAD-----KAGVSLSIN--SSSIQLWADPDRIIQTLTNLFSNAIKFSEPGSTVYLMTELQKDQVLVT
VQDTGRGIPEDKLESIFERFQQVDSSDSRNHDGTGLGLAICKSIVQQHGGKIWVKSVLGQGSSFYFTLPI---------------
>tr|K9V772|K9V772_9CYAN Multi-component transcriptional regulator, winged helix family OX=1170562 OS=Calothrix sp. PCC 6303. GN=Cal6303_5064 PE=4 SV=1
--KILIVEDEELMAEALTAVLTNQNYVVEIASDGEAGWELIKDFDYDLLLLDVMLPKLDGISLCRQIRNQLQLPILLLTGRDNSHDKAIGLDAGADDYLV
KPFDEEELLARVRALLRRGSVTSQP-----------VLEWGKLRLDPISCEVSYDHHLLPLTPKEYALLELFLRNSRRVFSCGMILEHLWSYEDTPGEEA
VRTHIKCLRQKLKAGGVSSSIIETVYGIGYRLKSGEEITLAGSLGTFGFPEGSKILILAVLFLVGPELVTRIINRLERMKRKTDEKN-------------
---------------QHQRTQEALKNSQARLAGVVEIADDAIISIDDNQRITLFNQGAEKIFGFTASEVLGRP-LNILLPSCFAQTRQYVTDFGKSQVQA
RKISGKGSEFPAEASISQLKLGDDTIYTVYLQDISERKEIERMKDEFVSVVSHELRTPLTSIHGSLGMLSSGLIKAEQGKRLLQIAADSTERLVRLINDI
LDIERIESGKVEMEKQTCDVSDAIHQAVNIMQPLAD-----KAGVVISVA--ASNYSIWADCDRIIQTLTNLLNNAIKFSKAGDIVSLAVQQQDKEVLFS
ITDTGRGIQQDKLETIFERFQQVDASDSRKQDGTGLGLAICKSIVQHHQGQIWVESVLNQGSTFYFTIPL---------------
>tr|K9XEV9|K9XEV9_9CHRO Multi-sensor hybrid histidine kinase OX=1173026 OS=Gloeocapsa sp. PCC 7428. GN=Glo7428_2092 PE=4 SV=1
-ARILLADDNADMRDYLK-RLLSQQYEVEAVADGRAALTAIRQRIPDLVLSDVMMPNLDGFELLRSLRSTQEIPLILLSARAGEEARIEGLQAGADDYLI
KPFSARELLARVEATLKLAQLRREATQREQTAQQAAQID-QILDRMTDAFVALDR--DWRIIYQNTE----AERLNR--KPRSQIIKTHW--EEWTASVG
TNVEYQYRRAMAEQVPVHFEHY--------Y-SPP-------------------------------DYDIWLE-------------------IHAYPSEQ
G----LGIFYRDITDRKRAELQELRQSEAQFRQLADAMPQQVWMTDAQGLTQYVNQQWTDYTGLTIEQTHDIRYTQVIHPDDFEATSERWQTALMTGMPY
LKATDAYRWFSRAIAIRNEQ-GQIVQWFGTSTDIEEFRRAQAERDEFLAVLSHELRSPLNPILGWSKLLQQGKLDATTKT-ALDTINRNAQLQVQLIDDL
LDISRILRGKLSLNVLPVDLSAVISAALETVHLAAE-----AKSIDLRTILDSGLSQVLGDAGRLQQVIWNLLSNAVKFTPHGGRVEVKLATSKSVAQIT
VSDTGKGIKPDFLPYVFEHFRQEDGATTRKFGGLGLGLAIARQIVEMHGGQIYVESPEEQGATFTVQLPL---------------
>tr|B1ZVG7|B1ZVG7_OPITP Multi-sensor hybrid histidine kinase OX=452637 OS=Opitutus terrae (strain DSM 11246 / PB90-1). GN= PE=4 SV=1
-ARVLLADDNADMRDYVM-RLLREHYDIAAVADGQAALALVRHWKPDLVLADIMMPGLDGFELLQALRETQQLPVILLSARAGEESRSEGLEAGADDYLI
KPFSARELLARVQSQLHLAELRRKAEAKVTASEA--RLA-QLVAMLPAGIYTVDA--EGRITFYNPR----AAEIWQ--APYAEFARPMP--TVLRNLVT
NEIEAVFQQASIGIMECDLEGR--------I-LR---------------------------------CNPWRDLCPPEEVGENRGDRPSFTGERRYRRKD
GSVGWIDIFATDITERKRAE-AELRETEERFRVAADNAPVLLWIADTDKQRTWFNQPWLEFVGRTLEQEVGLGWLDNVHPEDRDHVLEVFDTAFERRGPF
IRHDGEYRWMVHGVPRQQDE--EFVGYIGSCVDITDRRLAEAERDDFLAALSHELRTPLSPVLLLASDAAADPQLPPVRA-DFETIRKSVELEARLIDDL
LDLTRIVRDKISLDLREVDAPVALRDALINVRAEFE-----AKRIGLVLDLSPEPQFVRADPVRLQQVIWNVLKNAVKFTPAGGRVTIRIDHERRRLVLA
VADTGIGMTAGEIERAFEAFAQGDHAGSGGFGGLGLGLAISRRVVELHGGSITAQSPRGRGAVFRIELPL---------------
>tr|K9TYP1|K9TYP1_9CYAN PAS/PAC sensor hybrid histidine kinase OX=251229 OS=Chroococcidiopsis thermalis PCC 7203. GN=Chro_2201 PE=4 SV=1
-TYILLADDNADMRDYVK-RLLGREYEVEAVSDGLAALAAVRDRLPDLVLTDVMMPGLDGFGLLQALRATREVPIILLSARAGEEARVEGLEAGADDYLI
KPFSARELLARVEATLKLSQMRQEAARREQ----------IILERVTDAFIAFDR--EFRYTYVNPA----AAKLTQ--KTPEELLKTLW--EVFPDTIG
SRFESEYRRALFEQVKVEFEEY--------Y-QP---------------------------------YDMWVE-------------------VHAYPSSS
G----LSLYYRDISDRKQAE-EALRKSEELKGRILESSQDCIKVLSLDGRLLYVNTGGLALLEIDNPTALDTNWLDYWQGEDRQSAEAA-IAVAKAGNVG
CPAKGKPKWWVIITPIRDAS-GIVAQLLSISRDITKQKQDAAERDEFLAVLSHELRSPLNPILGWTKLLRSRKFDAQTDR-ALETIERNAKLQTQLIEDL
LDVSRILQGKMALNITSVNLTTTIEAAIETVRLAAR-----AKNIQIQTQFAPNVGLVCGDANRLQQVVWNLLSNAVKFTPSGGRIEVSLMGVASGVEIQ
VSDTGKGINSDFLPYVFDYFRQEDGTTTRKFGGLGLGLAIVRHITELHGGTVKAESLEAKGATFTVSLPL---------------
>tr|Q3ME76|Q3ME76_ANAVT Multi-sensor hybrid histidine kinase OX=240292 OS=Anabaena variabilis (strain ATCC 29413 / PCC 7937). GN= PE=4 SV=1
-ARILLVDDNADMREYVK-RLLSRHYVVETATDGLAALEALADHLPDLVLTDVMMPRLDGFGLLSALRSTREIPIILLSARAGEEAKVEGLEAGADDYLI
KPFSARELLARVEATLKLAQLRRDAMEQQQTAKQ--NVE-TILSSINDGFYVLDR--DWRFTYVNDR----LCKIIS--MEREDILHSIW--DLFADTIG
TDIDLQFQRAFNEQTSVQFEYL--------Y-VT---------------------------------WNRWYE-------------------HRVYPSPD
G----LTVFAADITERKQAE-LERRHYINQLQGLTRAALAINSALSVEQVLQVITDQAASIIGSHQSVTIGQNWISAIFLSDKYTQWQNYDVKPDRSGIY
LNLEAHPQWRFLAAPLVGRN-GQNIGLIAVLVQLAQMASVSVENDEFLAVLSHELRSPLNPILGWSRLLQNGKLDEAAKQ-AVNIIERNAKLQVELIEDL
LDISRILQGKLSLTSSPINLASVIKGAIETVRLAAE-----ANSIRIEVNLDGEIGLVSGDSTRLQQVMWNLLSNAVKFTPTGGLVEIRLEQVGNQAQIS
VSDTGKGISPDFIPYVFDYFRQADSATTRKFGGLGLGLAIVRHLVELHGGTIHAESQEGMGATFTLKLPL---------------
>tr|B2IWI6|B2IWI6_NOSP7 Multi-sensor hybrid histidine kinase OX=63737 OS=Nostoc punctiforme (strain ATCC 29133 / PCC 73102). GN= PE=4 SV=1
-ARILLADDNSDMRDYVK-RLLSQQYEVESVADGLAALDSARGRVPDLVLTDVMMPGLDGFGLLQELRATKKVPIILLSARAGEEARVEGLEAGADDYLI
KPFSARELLARVEAALKMAHLREEAMQREQVAKA--HLE-TVLAGIQDQFFVLDR--EWHYTFVNDR----VAEVVG--IQKEELLRIIW--ELFPDVAK
SEFYTQVHRAMAEQTVVQFEYF--------Y-PA---------------------------------WQRWFE-------------------NRVYPFGE
G----VSIFVTEISDRKQAE-KALRESEEQFRNMADNAPFMVWVTDTNNYCTYLSRSWYDFTGHNEETSLGFGWLNAVHPEDCDEVRNIFLEASKRCEAF
LHKDGEYRWTNAANPWFGVD-GQFKGYIGSVIDITERKTAEAERDEFLAVLSHELRSPLNPILGWARLLQTREFQPAIKK-AIATIERNAKLQAQLIEDL
LDVSRILQGKLNLKMFPVNLVLVIEAGLETVRLAAE-----AKDIQIQTMLDASLGQVLGDSDRLQQVIWNLLSNAVKFTPEEGKINIQLERIDSQAQIT
VSDTGKGISPEFLPHVFEYFRQADGTTTRRFGGLGLGLAIVRHLIELHGGTIWAESLEGQGAIFRVRLPL---------------
>tr|K9W072|K9W072_9CYAN PAS/PAC sensor hybrid histidine kinase OX=1173022 OS=Crinalium epipsammum PCC 9333. GN=Cri9333_2944 PE=4 SV=1
-ARILLADDNTDMRDYVK-RLLSQQYEVEAVPDGLAALSAARQRLPDLVLTDVMMPGLDGFGVLQELRNLRKVPIILLSARAGEEARVEGLEAGADDYLI
KPFSARELLARVEAALKMARLREEAMQREQVAKA--HLE-TVLSGIQDQFYVLDR--EWRYTFVNDR----VAKTVG--YSKEDLLKNIW--ELFPDVTS
SLFAQELHRAVKEQTVVRFEYF--------Y-PS---------------------------------WQRWFE-------------------NRVYPFNE
G----VTIFVTDISDRKQAE-KALRESEERFRNMADNAPFMVWVTDPTGYCTYLSQSWYEFSGQTEATGLGFGWVDAVHPEDREYAKKTFLTANERGDAY
LRKDGEYRWVDAAHPWVGVD-GQFKGFIGSVIDISERKQAEAERDEFLAVLSHELRSPLNPILGWTKLLQSRKYDEQTKR-ALETIERNAKLQTQLIEDL
LDVSRILQGKMVLNIAPVNLVTTITSAIETVRLSAE-----AKQIQIQTLFTAHVGQVMGDAVRLQQIVWNLLSNAIKFTPSGGQVIICLEQVGMNIQIQ
VKDTGKGIKPEFLPYVFEYFRQEDGKTTRKFGGLGLGLAIVRYLTELHGGTVQAESLEEMGATFTVTLPL---------------
>tr|E0ULK6|E0ULK6_CYAP2 Multi-sensor hybrid histidine kinase OX=497965 OS=Cyanothece sp. (strain PCC 7822). GN= PE=4 SV=1
-SRILIADDNADMRDYLK-RLLSQQYEVEAVVDGLTALKAIHSCHPDLVLTDVMMPGLDGFELLKSLRATQHIPIILLSARAGEESRVEGLEAGADDYLI
KPFSARELLARVEATLKLSYLRQEATRREQAARV--RLE-NVLAQINEQFIVLDQ--QWRYSFINDQ----VIQVTG--KSNEELLHNIW--DLFPDLVN
SPFYTECHRAVAEQTVVQVEFF--------Y-WP---------------------------------WQRWFE-------------------NRIYPFAE
G----VTILVSDISARKQAE-KELRESEERFRQMADNAPVMVWVTDPTGYCTYLSKSWYEFSGQNEETGLGFGWLDAVHPEDSEDSRNIFLAANKCQEAF
LRFDGEYRWADVGSPWFGLE-GEFKGYIGSVIDISERKAAEVERDEFLAVLSHELRSPLNPILGWAKLLQTKKLDGAFKQ-ALSTIERNAQLQAQLIEDL
LDVSRILQGKISLNPIPVNLASIIRHSIETVYLAAN-----AKSIDIQTTLDETVGQILGDPARLQQIVWNLLSNAVKFTSTGGRVEVLLESVGQSAQIT
VSDTGKGITSEFLPYVFDYFRQADSTTTRKFGGLGLGLAIVRHLVELHGGTVGAESPENQGATFWVKFPL---------------
>tr|B7KDV4|B7KDV4_CYAP7 Multi-sensor signal transduction histidine kinase OX=65393 OS=29155)). GN= PE=4 SV=1
-GRILLADDNGDMREYVK-RLLSQYYEVETVADGIAALEAIRRHPPDLVLSDVMMPRLNGFELLQELRRTEELPIILLSARAGEESLVEGLKSGADDYLV
KPFSARELLARIEATLKMAQLRQQAAQKEQAARQ--QIT-NIFESITDGFVAFDH--QWRFTYVNQQ----AAQMLN--QSREDLLNQIW--ELFPETIG
QECYQQLHQAFNEQITLTFEEF--------S-PV---------------------------------FGRWFH-------------------LRVYPSSE
G----LSVYFRDITKAKENDLQALRESESRFRVMADSAPVLIWMSGTDGLCNWFNQNWLEFTGRTLEQELGNGWAQGVHSDDYNFCLETYLSAFDQRIGF
LRADGEYRWVDNGKPLFTPE-GIFSGYIGSCVEITEQKEANEEKDQFTYIVSHDLKAPLRAIANLSQWIEEDDIIPPSQQ-QIELLRQRVYRMDQLINNL
LDYARI--GRSEATKERVEVAQLLEEIIDSL---AP-----PPTFTLE--IDLPMPTLMTEKLLLSQVFSNLISNGIKHHGKDGKLKISVQEQNNFYQFL
IADDGQGIPVDYQEKIFAIFQTVKSKDNKD--STGIGLSIVKKIVEIQGGKIMVSSQVGEGTTFSFTWPK---------------
>tr|Q7NGY8|Q7NGY8_GLOVI Two-component hybrid sensor and regulator OX=251221 OS=Gloeobacter violaceus (strain PCC 7421). GN= PE=4 SV=1
-PCVLVVDDNADMRAYIA-NLLKAHYEVVLAGDGVEALAAVERRMPDLVLTDVMMPRLDGFGLLAALRTTRALPVIVLSARAGEEATLAGLERGADDYLS
KPFAARELLGRVKANLELSRLRGETARLLHASEE--RAR-LAIRVGRLGTWRFVP--TSGVATMDER----MREIWG--EPEDTFQQAME--RIHPERVS
QAVDAALDPASAGTLEIDY---------------------------------------------------WPNG------------------SERWVSAN
G-----QVFFEDITERKRIE-QALAGSEQRYRLLAESIPQLVWTADVGGTLLDVNGRWSQYTGFTLEQVKKSGWESVVHPEDVPGLRRQWTAAIKAVAAY
MRTDGTYRWHHQAMPLMDGE-GRILKWFGTATDIEERKQLEAERDEFLAILGHELRTPLNPIIGWTQMLRRGKVGPDHDQ-ALEIIERNARLQTQLIDDL
LDVSRIMRGSLRIAPQPITLAAIVVCALEAVRGLAE-----QKQVQLFEQLRTTAPL-SADPTRLQQVVWNLLTNAVKFTPAGGQVQVRLESGGGMARLT
ISDTGVGIPAEFLPHLFERFRQADTKSTRE--GLGLGLFIVRHIVEAHGGTVQAESEEGKGAAFTVVLPL---------------
>tr|A6EGC4|A6EGC4_9SPHI Two-component hybrid sensor and regulator OX=391596 OS=Pedobacter sp. BAL39. GN=PBAL39_07720 PE=4 SV=1
-TRILIVDDNHDMRDYLV-RLLNPYFTIDTALNGQDALLKIGAQMPDLVLSDVMMPVMDGKAMLERIRSTLRLPVIFLSARAGEEARIDGLEMGADDYLV
KPFSAAELLTKVRAQIHISKSRGYAEQ---------QLR-NLLKQAPVAMVIYGP--RHVIELANSR----MLDYWG--RTEEETFKPLF--EAIPELAS
PEYRETGEPFISDEVPLMLNR----------------------------------------------FGKFINL-----------------TVEALRELE
GQ---VSGLIADVTEQVNAR-TSLEKINNTLQLAMEASNMGTWQTDLKTGLLQISETSRHIHGIPEREQLVYSEKELVVPEHVDRLGKAIENAVSTKGRF
IQTGGGRKWITTGMVELDES-GEPSTVIGTILDITESKEDE---NDFIGMVSHELKTPLTSLVGFTQLLRNAQKNQDLNF-SIEKTNRQLIKMSSLINGF
LNVSQLESGKIHLHLTDFRLDELIREMIADAGLAAS-----GYDFQVD-------LIINADRNKIGTVLTNLLSNAIKYGANSRVISIACSCTDGYARVS
VTDQGIGIKEADISKLFDRYYRIENNQTQHISGFGIGLYLSAEIIGRHHGKIWAESEPGKGTTLFVELPM---------------
>tr|K1Z834|K1Z834_9BACT Uncharacterized protein OX=77133 OS=uncultured bacterium. GN= PE=4 SV=1
--NVLVVDDNAANRSLLKALFEPQGHGVISAANGLKALDAMRREKIDLIISDILMPVMDGYRFCMELKRFKRIPFVFYTAYTDKEDEAFALSLGADRFYR
KPMDPEEFLEVIGELMR--------------HVREGTIQPREPAINEKDSLKGYSHRLTKKLDKKVRELQKELAARIEAEKRLEQVNRYLKGIIENANVW
FTVLDEHARVTIWNNAAEQIS-----------GYPSKDVVGHGDIWEWLYPDKEYRDEITAKAKAIIVEGEVVEDFETCIRRKDGETRVISWYSRNLTDE
QGKPVGSVALGRDVTRRNKAES--RKIARRYRQLFDANADALYVLDIDGRFIDANVAAEHRYQYSREELLG----------TSDRVRQSMID----AEWR
HKRDGTEFPVEIAPSIMDLGNGQKT-ILSAVRDITERKRAEK--------VAHDYNNILSVIIGYTELALLKVPPEDPLRDDLNEIYAAAGRSRDITRQL
LAFAR----QE----EMLDLNSAIESTFKILR-LI------GEDVDLVWRPEEGIRPVLMDPSQIDQILANLCINARDAIADVGRITIE-----EFVTLS
VSDDGCGMDRETQEKIFEP------TTKGVGKGTGLGLATVYGIVKQNNGFINVY-EPGQGTTFKIYLPN---------------
>tr|B2J7V1|B2J7V1_NOSP7 Multi-sensor hybrid histidine kinase OX=63737 OS=Nostoc punctiforme (strain ATCC 29133 / PCC 73102). GN= PE=4 SV=1
--VILIVDDAPINLEILFKLLEYYGLKVLVSEDGMNAIEIAENALPDLILLDILMPGIDGFETCRLLKKTQDIPVIFLTAITDKIDQIKGLNLGAVDYIT
KPLEHKEVLARVNIHLR--------------LRNLTKKLTEQNKRLEIEIFERQRVEEELRCHSAALDEWNNRYQALIQASGQILYDWYLDTNDIKYDGN
LEQILGYSIPEM-----------------------------LGGLNRWLELVHPDDRKLFNEEINRVLSAKERFHLEFRVGRKDGTYITVENNGYIFLDS
TGKVARMAGFVIDITEQQAALC--KNAEQKIREWLDITTDAIIVQDLITKIQFWNKGAEHLYGWMAEEALS----------SFGQLKNIQKTLVE-GQGE
LTKQGKEIIVASRWTLVNDNEGQAKSVLIVNSDITEK-------------IAHALNNTLTPILMTVQLLEAQL-LDEKSQQWLTIMKTNVKRTADLVKQV
LWFSR----GS----KTLQVQYLISEIENIIK-TF------SRVIEIRIDSEQNLWNIFGDATQLHQVLMNLCINARDAMPNGGILKIS-----SYVMIS
VCDTGIGIKREIVDRIFEP------TTKEVGKGTGLGLSTVLGIIKSHFGFVNVV-DVGKGTEFQVCLPV---------------
>tr|K9W9Q7|K9W9Q7_9CYAN PAS/PAC sensor hybrid histidine kinase OX=1173027 OS=Microcoleus sp. PCC 7113. GN=Mic7113_1195 PE=4 SV=1
--VILLVDDTPINLEVLLDLLEDSDFNVVVAEDGESAIEMAEYAPPDLILLDVLMPGMDGFETCRRLKATQDIPVIFMTALTENVDKVKGLNLGAVDYIT
KPLEHEEVLARVNIHLR--------------LRHLTKRLTEQNEQLQQEISERQRAQEEREQAFTALRQSESRFRRLVESNIIGIICTELNGSITDANDA
FLQIVGY---------------------------------------ERSELLRGNLRWDDMTPLEYRDLDEKAIAELITSGVCTPYEKEFIRSDGSHIPI
MIGAVLLEESQQSAVGFVLDLS--KIAEQKIRELLDITTDAILVRDLNRKIRFWNEGAERLYGWKAQEVMG----------TLDQLEESWKSLAE-GHSE
LTKEGKEIIVASRWTLVRDKNGQPKSILTVNTDITEK-------------IAHDLNNALTPMMMAAQLLECKL-PDEQSQQWLSILETNVKRAADLVKQV
LLFSR----GV----TPLEVGYLIKEIEKIVK-TF------SRAIEICSEPTQNLWTISGDLTQLHQVLMNLCVNARDAMPDGGTLQIS-----PYIVIT
VSDTGTGISREIIDRVFEP------TTKEIGKGTGLGLSTAIGIIKSHGGFVKVL-KVGKGTQFQVYLPA---------------
>tr|K9PCG5|K9PCG5_9CYAN Multi-sensor signal transduction histidine kinase OX=99598 OS=Calothrix sp. PCC 7507. GN=Cal7507_0585 PE=4 SV=1
-WTLLIIDDCAADRKIYRRYLLSDSYQILEADCAEDALVLCQEKHCDLILLDFCLPDMSGLELFAKLQQETPVAVIMLTGHGDEEVAVQAMKQGVQDYLV
KQLKPDVLQLAVRNAIKQSCL-QAQLSKTRELRIRQSLDLE--QILNTAVAEIQQ-----LLKCDRVMVYQFAKDIDGKIVAAYVDSIINQNAAILNLCQ
NNLGCRQAFSHFYETDWKIPELSNEIYEQELH-QF---DSKSNLVVPIN---------------LSHN--------DQREAQIWGLLIAYHCSGERQWQT
DDV----DMLDEVSVQLAIAIQQAE-----LLTQ--------------------TQAA---LG--------K-------E---KQ---------------
---------L------------------------------NALKSQIITTVSHEYRTPLTSIFAAASTLLQHGQLDKRQQRFLRIIEQKARYMSKLVDDM
LLVNQLELDKTKFKPIPLDLLQFFSDLMEQERKTGE-----NHELIFKIT--GNCQSFWGDRQLLQQIFVNLMSNAIKYSPDGGNIEFHLIGQESQVIFH
IQDEGIGIPIVDQEHLFQSFSRGSNVDTIP--GTGLGLAITQACVKLHGGDIVLSSQVGQGTKVIVSLPK---------------
>tr|K9UKB7|K9UKB7_9CHRO Bacteriophytochrome (Light-regulated signal transduction histidine kinase) OX=1173020 OS=Chamaesiphon minutus PCC 6605. GN=Cha6605_3910 PE=4 SV=1
-CNILIVDDSETDRATYRRYLESGGYQICDCETGEDALDFCDRHCPDVILLDYLLPDTDGLQFLEELTERKLPPIVMLTGQGNEAIAVEAMKHGVRDYLV
KGLTPQRLVNSVTNALTAQKL-QSQIDSQKRLKVGHSIDLA--EILQAGVDGARE-----LLECDRTMVYKLNPDLSGTIVSESVLPNCFHSHSISKYLN
G---HKVAISNIRAAELSPCYV-------EMLERF---QVKAVLVVPIL---------------LREVS-------PASAPTVWGLLIAHHCKTAREWKA
DEL----NLLDEMSVQMEVAIQKAE-----LVLDLQQTL----------AKQQAVDRQL--RD--------R-------V---IE---------------
---------I------------------------------EQTNDEFACIASHDLQAPLRGISNLADWLAKDLDKLPENQQQLNLIQSRVQQMNALINGL
LLYARV--GRENVDPTTVNISEILREVIETI---DP-----PADFKVHFA--SHLPTLTTQALLLKQVFANLIGNAIKYDRTDGTVEILVKDRDYFWQFT
VVDDGPGIAPEHHKNIFGIFQTLMGRDSNK--GSGIGLAIVQKIVESRGGSVWLESALGEGSAFSFTWPK---------------
>tr|B2IX88|B2IX88_NOSP7 Multi-sensor signal transduction histidine kinase OX=63737 OS=Nostoc punctiforme (strain ATCC 29133 / PCC 73102). GN= PE=4 SV=1
-WTLLIIDDCAADRKIYRRYLLKDSYQILEADCAEEGLALCQKIRCDAILLDFCLPDMSGIELFDQMQQETSVPVIMLTGRGDEEVAVQVMKRGALDYLV
KHLTQDVLQLAVRNAIKQSCL-QAQLSKTQELRIRQSLNLE--QILNTAVAEVQQ-----LLKCDRVMVYQFAPDTDGKIVASSVESLLAGSRGKI----
----CTLPPAPLPNPQSPIPYIYELGNCVSLKEQF---NTNANLVVPIN---------------LSNN--------GNPTPKLWGLLIAHQNSGERQWQT
DDA----QMLNEVSVQLAIAIQQAE-----LLAQ--------------------TQAA---LA--------K-------E---KQ---------------
---------L------------------------------NVFKSQIIATVSHEYRTPLTSILAAASTLAKHNQLDEKQQRFLGIIEQKARYMSKLVDNM
LLVNQFELEKPKFKPIPLDLLQFFADLIEQERETGD-----RHELIFQIT--GHTQGFWGDRGLLQQIFINLMSNAIKYSPDGGTVEFHLIGKESEVIFY
IQDRGIGIPIKDQENLFQSFCRGSNVDTIP--GTGLGLAIAKGCVELHGGDITLFSEVGQGTKVTVSLPK---------------
>tr|K9PTJ3|K9PTJ3_9CYAN Multi-sensor signal transduction histidine kinase OX=111781 OS=Leptolyngbya sp. PCC 7376. GN=Lepto7376_0324 PE=4 SV=1
-LTVLIIDDSPDERDIYEQFLLRDSYLTVGTDTGEDGLQLLDAHVCHLILLDFNLPDMNGLEFLEILQTSTQIPVVMMTGQGNEAIAVQAIKQGAYDYLV
KRITPESLQSTVRNVLKQSNL-QTRLHKSKQLRIRQSLDLE--QVLEQATVETRQ-----LLECDRVLLYKCELDMSGVIVAESVNSTCFQNNGAQYYVQ
GK--CTTI-NDIQRAGLTSCHI-------ELLERF---QVKANLVVPIL---------------LTTTSRN--SSDQSQSTQLWGLLIAHQCDEPRCWTI
EET----ELIKLLSLQLAIAIQQAE-----LLSK--------------------TERS---LQ--------R-------E---QE---------------
---------L------------------------------NALKSQIIGTVSHEYRSPLASILASASTLRIHGSLPEAQKKLLNMIENKVRHMNHLIEDM
LFFNQIERGQIPIQSTPVNISDFLLEQIEEYKLKKP-----SYAINLEVK--GTIEPFENDPKILGQIFNNLLSNAIKYSLDSRHIDIQLKGLASQVIVI
IKDYGIGIDIDDQDSIFEPFHRGANVGTIP--GTGLGLSIVQGCLDMCGGKISYTSEPNQGTKVTVGFPR---------------
>tr|F7T8K1|F7T8K1_ALCXX HAMP domain-containing protein 8 OX=1003200 OS=Achromobacter xylosoxidans AXX-A. GN=AXXA_26475 PE=4 SV=1
-RRVLIVEDDAHIAELLRLHLRDEGYAVEHAADGNEGMRRLEEGGWDALVLDLMLPGIDGLEICKRARATRYTPIIITSARSSEVHRILGLELGADDYLA
KPFSMLELVARVRALLRRTEALERNARI---DAG--SLRQHGVAIDPIARTASVDERRLELTPREFDLLHFFARNPDKVFSRLDLLNQVWGYQHEGYEHT
VNTHINRLRTKIEADPSNPQRILTVWGRGVQVRGRAGRAIMKRLTLTRLSAVFAMLLLACCGASAWLQISA---NLRYEQEVVQRLSSGLAQHLMMVNPA
VEVYLLDNDGRIVGDAAS--PGQIKRDRVDLAPVRRFLAGGALPIEGDDPRHLDT---AKVFSAAPVGRDEGYVYVVLQGEAHDALAMAASRSAVLTLWS
IALAGDGRALAKEISLLRR------SFVQMGRRISEQTRQDQQRRDLVANISHDLRTPLTSLHGYLETLLKDETLDAERRRYLDIALAQSRKVGRLAQEL
FELARLESGLVRLEPETFSLPELAQDVIQKFELAAE-----ARQQRLTTAMDQELPPVRADLGMIERVLTNLLDNAIRHTAPGGRIELSLEQARGGVQVR
VSDNGAGIPDALRAGLFTRASVLA---NGPRDGGGLGLVIVHRILQLHHSDIRLVERPEPGAVFEFDLPAA--------------
>tr|D5CFE0|D5CFE0_ENTCC Uncharacterized protein OX=716541 OS=NBRC 13535 / NCDC 279-56). GN= PE=4 SV=1
-KQILLVEDDHDIAALLRLNLEDEGYIITHEPDGGNALQCLEKQPWDAVILDLMLPNVDGLEICRRIRQTRYLPVIIISARSSETDRITGLETGADDYLA
KPFSVQELIARIKALFRRQQAMGQAQ-----SAG--NIQAHGLTIDPLARSVLLHGQIVDLTPREFELLYFFARHPGEVFSRLALLEQVWGYQHEGYEHT
VNTHINRLRIKIEKTLPSRRSFAPCGEKAINLRSRT---MMRRFSLSRLTLLFILLMMLCAAVACAVQLYS---SMQYGNAMVQRLSGGLAQQLMTFNPS
VELYVVSPDGDILADAAP--PGHIQRQSINLAPVQEFLSGAAMPVFGDDPRS-QN---KKVFSATPLGELKGYLYIILQGEESNALADMAWHKALWVLWS
MLLAGSMSAIRVEVALLRN------NFIELARKITHQADSDRQRREFIANISHDLRTPLTSLLGYLETLLKSATLTPEHQQYLATALRQGQKVRHLSQQL
FELARLEHGGIKPQRERFAMGELISDVAQKFELTAR-----TRELQLQIDVPGPLPLVYADVSMIERVVTNLLDNAIRHTPTGGKIRLAVWQENEKLQVE
VADSGTGVDAALRDDLFQRPSALN---PQAENRGGLGLLIVKRMLELHGGGIRLME-SVSGARFRFFVPL---------------
>tr|B2IZ13|B2IZ13_NOSP7 Multi-component transcriptional regulator, winged helix family OX=63737 OS=Nostoc punctiforme (strain ATCC 29133 / PCC 73102). GN= PE=4 SV=1
--KILIVEDDGLNAYTLTNLLTNQNYAVEVATDGDAAWDCIQAYDYDLILLDVVLPKLDGISLCRKIRSNLQMPILLMTGRNSSHEKAIGLDAGADDYLV
KPFDIEELVARIRALLRRPAVTSPPVLE-----------SGKLRLDPSSCEAVYARNLLPLTPKEFALLELFLRNSRRVFSCGMILEHLWSYEDTPQEEA
VRTHIKGLRQKLKAVGAPGDLVETVYGIGYRLKPLEEDKHIPNLKSQQQALMAVALILCILFLVGPELVTRIVNRLERM-KLRQRVTQGSRGAGGAEEVN
SPPSFSHRAINELQSQLQQTQEELRFSQARFARILDIADDAIISINGFHNITLFNQGAEKIFGYCAQEVIGQG-LDLLLPQRFFQAHRHVADFGQSARRM
REIDGSEFPA--EASISKIDMGDEIFYTVILRDVTERKQIERMKDEFVSVVSHELRTPLTSIYGSLGMLASGLLPTDQGKRLLQIAADSTERLVRLINDI
LDIERIESGKAKMEAEICNIVDLITQAVNVIQPLAD-----KAGVTLSIS-AL-SGQVLADCDRIVQTLTNLLSNAIKFSSAGSTVWLGAQQEGDEVLLT
IKDTGRGIPTDKLESIFERFQQVDSSDSRNHDGTGLGLAICKSIMQQHGGRIWAESILGEGSTFYVTLPL---------------
>tr|K8GH48|K8GH48_9CYAN PAS domain S-box OX=864702 OS=Oscillatoriales cyanobacterium JSC-12. GN=OsccyDRAFT_4607 PE=4 SV=1
--KILVVEDDGLTAEALIATLSNQNYVIEVASDGEAGWELAQTFAYDLILLDVTLPKLDGIRLCQRLRSQCQTPILLLTARDSSHDKAIGLDAGADDYVV
KPFDPEELAARIRALLRRHQTISQPVLE-----------WGDLRLDPGSCEVTYQTQLVSLTAKEYALLELFLRNNRRVFSCGAILENLWSFAEIPSDEA
VRTHIKGLRQKLKAAGAPANLIETVYGIGYRLKPLEKEKVEAQVEEKTRA--AIALILCIVILVGPELVTRIINRLERI-RFLRDLA------NNLAECQ
PAEAALRKVKDELRSELKQIEEALRVSQMRFAGILDIADDAIISTDGKQRITLFNQGAEKIFGYTAAEAIGQP-LDLLLPTRFVVAHQHVAEFGQSARRM
REINGEEFPA--EASISKLKLNQETIFTVILRDTSERKVVERMKDEFISIVSHELRTPLTSIHGALGMLASGLLDAEAGKRLLDIAVDSTERLIRLINDV
LDVERIESGKVTMDKRLCNVADLMTNAADVMQAMAE-----KFGVTLSLS-PL-STMVWADRDRIIQTLTNLLSNAIKFSPPGATVWLTAEHSTPSILFS
IKDQGRGIPADKLETIFERFQQVDASDSRNQDGTGLGLAICRNIVQQHGGRIWVESVLGKGSTFYFTLPI---------------
>tr|K9XNK4|K9XNK4_9CYAN PAS/PAC sensor hybrid histidine kinase OX=111780 OS=Stanieria cyanosphaera PCC 7437. GN=Sta7437_0491 PE=4 SV=1
-ARILLADDNNDMRDYLQRLL-SQHYQVETVADGLAALSVARQNLPDLILTDVMMPELDGFELLRSLRNTQSIPIILLSARAGEEARVEGLAAGADDYLI
KPFSARELLARVDSTLKLAQLREANQREQKLEKEAVQQQLSDLDKMTDAFVMLDRDWRINQKPRSIEHNHHLEIHAYDISEQADLVPDLLWRNYTGQSSG
DLISLTNFQNAVNASPFKHEYRIRGRAEPLFDQWFGAATDIHQQRTALEALRISTAKVVIVLYLVVYVNNYLIHPEDLENFVKRVAKDGNLLHEYFQASN
AVFKSLLNVLEDITERKQ-AEQALRESEARFQTLVKNMPGMVYRYQENNTFTYVSCGSLKLLAVEPELILQNAEFFWRHPDDLQSLSPAYDKQNLSTWKV
PAQPGVERIWLEFLP-LKNGED-IIGINVVCEEITFRKQAEIELDEFLAVLSHELRSPLNPILGWSKLLQTQKFDQDTNR-ALETIERNAKIQVQLIEDL
LDISRIIRGKLSLTVYPVSLVSIIEAAIETVNLSAQ-----AKSIAIKTKFEPGVGQVSGDPSRLQQVVWNLLSNAVKFTPEGGQIEVKLKSIGFQAQIS
VKDTGRGISPDFLPHVFDYFRQEDSATTRRFGGLGLGLAIVRHLVELHGGTVAAKSLEGQGATFMVRLPL---------------
>tr|K9PMP0|K9PMP0_9CYAN PAS/PAC sensor hybrid histidine kinase OX=99598 OS=Calothrix sp. PCC 7507. GN=Cal7507_4317 PE=4 SV=1
-ARILLVENNADMRNYVKQLLVSQQYEVETVTDGVAALAAMRQHRPDLVLSDVMMPRMDGFELLRSLRSTREIPMIVLSARAGEESRLEGLQAGADDYLI
KPFSARELLARIEVNLKLSRLREALQREQELQSETAKATLENLASIKDQFLVLDHEWEVIGIPRKFYTQYFFENRIYEITDREQSTEAIWCFEMYGASSP
TDLNLQYLRAFIHSGLVDAESYEVDNLVGIIERAWGTQRDITDRKRAEAALQFRQDVFWIVDFLL-YISPANIHPDDREMAANQCIQTGSLSIEYVRDRG
YNLRRIAGIAEDITERKQ-IAAALQESTAILNAINQTSPTLIFVKDRQGKMLMANPATVQAIGKPEAAIVGKTDFDFHRAEAEQIVDERMREAPLAIIKA
YQAEGRMRRWHLAVP-LKNPQGRVIKWFGTATDIEDQKQLDQQRDEFLAVLSHELRSPLNPILGWSRLLLNGKLDATTTQ-AVQIIERNAKLQAQLIEDL
LDISRILVGKFRLENAPVNLAAIIVAAQETVQLAAQ-----AKSIQIQTVLDPNIEQVLGDAARLQQVIWNLLTNAVKFTNPGGRVEIRLDGVDSHAQIQ
VTDTGKGIHPDFLPHVFEYFRQEDGATTRKFGGLGLGLAIVRHLVELHGGTVRAASPEGEGATFTVRLPL---------------
>tr|K9WJJ5|K9WJJ5_9CYAN PAS domain S-box OX=1173027 OS=Microcoleus sp. PCC 7113. GN=Mic7113_4293 PE=4 SV=1
-AHILLADDNADMRDYVKRLLVTQGYEVETVGDGIAALARIHERTPDLVLTDVMMPRLDGLGLLRSLRDTREIPIILLSARAGEKSRIEGLEAGADDYLI
KPFSARELLARVEASLKLAQMREAASREEVLEVQSAKDTLENLSRIRDQFLALDQDWEVTGKSREFQIEYFFENRIYDITNRTDTVPALIAYVWFGKLV-
EEFAYQYIRSDIEKASVTSELWVPFQYIPDIDGFFAMITDLTDLKRTQEAFRFSQATVGIAQMLFVLVNQKITHPEDLPELFHRLVTRGSYALEKVSNYV
AAIESAISVVLDISERER-LLQELAIERARFEAVLRQMPAGVMIADASGKLVLTNEQAKQIVGYDYEQSIQLAEYNFERSDGQLYNNFHVENTPMAVVKQ
YTKDGDIVHWY-NSS-LRDELGRMTSVLSLVLDVTERKRAEQERDEFLAVLSHELRSPLNPILGWSRLLQTRKFDAATAE-ALATIERNAKLQAELIEDL
LDVSRILRGKLSLNITSVALTSTIQAAMETVRLAAE-----AKSIQMSTKLEPQVGKVSGDASRLQQVVWNLLSNAIKFTPPGGRVDIQLERIDSYAQIV
VSDTGKGIPVDFLPHVFDYFRQADATTTRKFGGLGLGLAIVRHLVELHGGTVQADSAEGQGATFTVRLPL---------------
>tr|K9XK66|K9XK66_9CHRO Multi-sensor hybrid histidine kinase OX=1173026 OS=Gloeocapsa sp. PCC 7428. GN=Glo7428_4584 PE=4 SV=1
-AHILLVDDNADMRDYVKRLL-SQQYQVKAVADGIAALEAIRQQRPDLVLTDVMMPRLDGFGLLRELRTTREIPIILLSARAGEESCVEGLAAGADDYLI
KPFSARELLARVEASLKLARLREAAQREQTI-----------LERVTDAFVAFDRDLQIMRKTFDIEQAEYLEGQLYDITQRANAMPQIVWIAYTGLTLA
TQITYEIWQSCLATGLYQTEFRLRRRAVPICNHWYGTLTDIDDRKRTEEALRFRAKDYAIFTLLITSWNSGIFTPEDNLADREMALHAGQAENERASGIV
MPLQGFVKIMQDKTTQRQ-ANERLH---------------LLY---ETTSHLLAAENPLAIMNNLFSKLQTELELHFMEKDGQQML------AQIAT-QG
--------------------------LQATCDQVA----VALERDEFLAVLSHELRSPLNPILGWSKLLQTRKLDEATAQ-ALATIERNAKLQSELIEDL
LDVSRILQGKLNLNVAVVNLASTIQGAIETVRLAVE-----AKSIELTVNLDFNV-EVSGDATRLQQVMWNLLSNAVKFTPTGGRVTVELTQVRNQAQIK
VSDTGKGIQPDFLPHVFDYFRQEDGKTTRKFGGLGLGLAIVRHLVELHGGTVEVESRENQGATFTVQLPL---------------
>tr|F5UJC3|F5UJC3_9CYAN PAS/PAC sensor hybrid histidine kinase OX=756067 OS=Microcoleus vaginatus FGP-2. GN=MicvaDRAFT_0889 PE=4 SV=1
-SKILLADDNADMRDYIRRLL-SRSYIVQTVADGVAALTAIEKNPPDLVLTDVMMPGMDGFELLRSLRSTQDIPIILLSARAGEESRIEGLAAGADDYLI
KPFSARELLARVEASLKLARLREATVRERTI-----------LGRVTDAFMEMDLDFRVSRTPLEFEFEEYVEVHVYDINDRGS---AITGINILGWTPD
EFVSVSEADS---GNSLRFENRYRHNAQPYPE-IYGTAVDITD-QRAQQALRSRSI--AFFALEFTYLNQF--------------------AGSVYEARS
YPAHGITVYFKNVTDQIQ-AEAVLRQTSAELERQLQK---FIYTFDLSGRFMDVNKPLLDLWQKSFAEVIGKNFF-------------------------
---------W---F----DAEGAVEMVAGLTRDITDRKQAEAERDEFLAVLSHELRSPLNPILGWSKLLQQGKLGAATAS-ALATIERNARLQSQLIDDL
LDISRILSGKLSLNRMSVDLNMVISAALETVRLAAE-----AKSLQIQTTFSPSLGMVMGDSGRLQQVIWNLLSNAVKFTPEGGQITVRLTQTKTYAQIQ
VIDTGKGINPDFLPYVFEHFRQEDGAITRKFGGLGLGLAIARQIVELHGGRIWVESREGQGASFTVELPL---------------
>tr|K9VQ37|K9VQ37_9CYAN PAS/PAC sensor hybrid histidine kinase OX=179408 OS=Oscillatoria nigro-viridis PCC 7112. GN=Osc7112_5370 PE=4 SV=1
-PDILLADDNADMRDYIRRLL-SGSYIVQTVADGVAALTAIEKNPPDLVLTDVMMPGMDGFELLRSLRSTQDIPIILLSARAGEESRIEGLAAGADDYLI
KPFSARELLARVEASLKLSRLREATVRERTI-----------LGRVTDAFMAMELDFRVSRTPLEFEFQEYLEVHVYDINDRGS---VIAGINTLGWTPD
EFVSIAEADS---GNTLTFENRYRHNAQPYPE-IYGAAVDITD-QQVQQALRSRSI--AFFAVEFTYVNQS--------------------AGSLYEVRT
YAAKGITVYFRNVTDRIQ-AEAALRQSEERYRTLFES---VLFDANIDYRFLEINPGFEQ--QTGLRQAVGKT---------------------------
---------W---Y----TGQPESRKVAVVFKDISDRVSHEAERDEFLAVLSHELRTPLNPILGWSKLLQHGKLDAATAS-ALVSIERNAQLQLQLIDDL
LDISRILSGKLSLNAMSVDLNMAISAALETVRLAAE-----AKSLQIQTTFSPGIGMVMGDSGRLQQVIWNLLSNAVKFTPQGGQIRVRLTQTGSYAQIL
VADTGKGINPEFLPYVFEHFRQEDGAITRKFGGLGLGLAIARQIVELHGGRIWVESREGRGATFTVELPL---------------
>tr|H0PV58|H0PV58_9RHOO Putative uncharacterized protein OX=748247 OS=Azoarcus sp. KH32C. GN=AZKH_2096 PE=4 SV=1
--RIYVVEDSPS-QAAVMRLLVQAGYEVEVFGNGRAALDALNGQ-PDLILSDIAMPVMDGLALCEAVKRWRHIPVILV-TASKFEELVNGLNALADGYLN
KPYNPNVLIQTVSTLLQRKAAGAIRPAQTSTTLPVTQGGKTYPLV-------------------------------------------------------
------------------------------------------------ADRARVFDFFSIALLNSSVQAQELEEREKKL-----KETNVQ----------
----------------LARHIELLSASEERFRSLIAAVPDIVYKLDANGNFTFLNDAITRL-GYDPGELVGVPSAELVLPRLSGSAAPNAPKLFNERRTK
ERLGSALVHVEVSMGLYGQAERKFIGTVGVIRDITERLLFERAKSEFLSSMSHELRTPLNAIMGFSQLLDPEAPLDDNQKQCLQYIVDGGKHLLRLIDDI
LDLAKIESGGNTLDIHSTDPAPLLKFALEASEKLAR-----PRQVAVVAELPERLPNVMIDATRFRQVMLNLLSNAIKYNRPEGEVRLTAETRDGRLRVS
VSDTGHGIPVERMPELFQPFNRLG-FASSGIEGTGIGLVITKRLVESMGGEIGVDSDVGVGSTFWAEFPV---------------
>tr|K9QGY3|K9QGY3_9NOSO Multi-sensor signal transduction histidine kinase OX=317936 OS=Nostoc sp. PCC 7107. GN=Nos7107_4343 PE=4 SV=1
--TVLIIDDSPEDREVYRRYLLQYSYTILESESGEEALELYRQFQTDCILLDFLLPDMDGLEFLAELPKKVIPAVVMLTGYGNEAIAVQAMKSGVHDYLV
KGQTTAGRLH---------STIHSAIAQVKLR---QEL---------------------QQSE---ARLRESQ----QFIERETTPGILYVYDLLE-RRN
LYLQVNKL---LGYSS------QQIQDLGFLIKLMYPEDFFLHLQKIATVKD------SEILEWHWFYSRD-TVFIRN--------DDGSP--R------
---QIVGTAYDITN--RKQTEAQLSLSNERFQLAAAAVNCLIYDWNIPENTVERTEGLTRILGYSAQEAEPEWWMEKIHPEDRKLLQSSFEKMSVNDDYY
VRHKNNQYRYVLQGVITRDQNGQLLRAVGSTTDISDRKYQEAQRDEFVAMVSHDLRSPLNAILGWAQLLRTKEFDKERVNRALETIERNALSQAKLLEDL
LNMSQILRGKLHLELKPVDLGAIVREAIQTAYPAAN-----AKNIHLECVIDQPIPAITGDGDRLLQVLGNLLSNAIKFTPDGGQINVKLFPHEYHAEIT
VTDTGIGISPEFLPFVFERYRQDYRI--PKQGGLGLGLAIAHYLIELHGGTIQALSGEGQGSTFSIKLPW---------------
>tr|K9PDH4|K9PDH4_9CYAN Multi-sensor signal transduction histidine kinase OX=99598 OS=Calothrix sp. PCC 7507. GN=Cal7507_0300 PE=4 SV=1
--TVLIIDDCLEDREVYRRYLLQYNYTILEEESGERGLEVCRQFQPDGILLDFLLPDLDGLEFLEQLKKAAMPAVIMLTGYGNEAVAVQAMKRGVQDYLV
KGQTTGDLLR---------STVHSAIKNAQLS---QEL---------------------QRSEEKKERLQESQ----RLIERETTPGIVYVYDLVE-QRN
VYIQVNKL---LGYTA------QQIQAQSFLPQFMHPEDIAIFFQKFNSAKD------GDILEWRWFFSRD-TIFTRN--------ADGSP--R------
---QIVGTAFDITE--RKLAEVALRQSEERYRYLSDAVPQIVWISNAEGECEHINQKWDEFTGQPIEQA--GFWTEIVHLDDIPGMMEKWLAAVHTGELY
YRSRDGTYRWHLRGLPMKDEQGDIIKWFGTSTDIDDRKQLEAERDEFVAMVSHDLRSPLNAIMGWAKLLRTQQMDTASINNALETIERNAKSQATLLEDL
LNMSRIIQGKLQLNLGKVNLAAIVAGAMETAYPSAH-----AKSICLESVVDKSIPPIRGDWNRLLQVLGNLLSNAMKFTPSGGQVEVKLLRNGSNAEIT
VSDTGIGISPEFLPHVFERYFQGDRI--HKQSGLGLGLAIARHLVELHGGTIEVASGVGLGSTFTIKLPC---------------
>tr|K9RHZ1|K9RHZ1_9CYAN PAS domain S-box OX=373994 OS=Rivularia sp. PCC 7116. GN=Riv7116_4288 PE=4 SV=1
--TVLIIDDCLEDRNTYCRYLQKCNYQFLEQEYGKDGLEACKQVQPDIILLDYMLPDINGLEFIQELQSDTSPPIIMLTGEGSEKIAVQAMKYGVEDYLV
KANTTAKILR---------LTVRNVIEKKNLQ---QKL---------------------EVSKRRKQALQESQ----HLIQRDTTPDILYLFDLEE-QRN
IYIQVQQR---LGYSP------LLIKKMGLFKNLVHPDDLKNHLKKFASIKD------GEILPWHWFSSRD-TVFTRS--------SDGKP--Q------
---QLLGVVREITA--QKQSEEALRESEARFRYIYESNMLGIMFWKTNGKVIDANARFLEIIGYSREDLQAIRWDEFTPPEWKEVDREAIEQIKNNRVCH
YIRKDGSRVPIVGACLLENSINTGVSFV---IDITERKRIEKERDDFVAMVSHDLRSPLNAILGWSQILRSSSKDEAIKNRGAEIIERNAKAQDALIQDL
LDISRIIRGRLQLQMIPVKLESILNNAIDSAYPVAI-----AKNIHLESEVDSNINNMLGDAKRLQQVVDNLLSNAVKFTPESGHIKVNLRKIENNAQIK
VIDTGSGISKELLPLIFERFHQGSNI--EKQQGLGLGLAIARHLVELHNGKITAESGEGKGTTFTVILPL---------------
>tr|Q3MEF7|Q3MEF7_ANAVT Multi-sensor signal transduction histidine kinase OX=240292 OS=Anabaena variabilis (strain ATCC 29413 / PCC 7937). GN= PE=4 SV=1
--TVLIIDDCAEDRQVYRRYLQQHHYTILEQESGEEALELCRQLQPDVILLDFLLPDQDGLELLAELQKGSMPAIVMLTGYGNEAIAVQAMKSGVHDYLV
KEQTTAERLR---------STLHSAIIQTRLR---QEL---------------------SRSQ---EQLHDSQ----KFIERETTPGILYVHDLVE-KRN
VYIKVGNL---LGHTP------QTIQNLGFLITFMHPEDLPQVFQQFDSAKD------GDIIEWCWFFSRN-SVFMRN--------SDGSP--R------
---QIVGTAFDITA--RKQAEEELRSSNERFRLAAAAVNSLIYEWDIKKGTVTRTEGLTRILGYSVEEATPEWWQEQIHPDDQDFLVEQFQNPPVNQTHY
IRHKNNQYLYVLQGIITRDENGQPVRVVGSATDISDRKLAEAERDEFVAMVSHDLRSPLNAILGWSQLLRTRQLDESTFTRALETIERNAQSQSKLLEDL
LDMSRILRGKLQLEFCLVELPAIIGVAIETAYPSAK-----AKDIHLKSVIDESIPLIPGDINRLLQVLGNLLSNAIKFTPPEGQITVQLSYTDSEAHIT
VIDTGIGIKSEFLPYVFERYRQADCQ--HKQHGLGLGLAIARYLIELHGGAIHVNSGEGQGTTFTIKLPL---------------
>tr|K0NJL8|K0NJL8_DESTT Two component system sensor histidine kinase OX=651182 OS=Desulfobacula toluolica (strain DSM 7467 / Tol2). GN= PE=4 SV=1
-VHLLIVEDSPTQALKIQYFLEQNGYKVSMAKDGEQALVMLKDIIPTIIISDIVMPKMNGYELCDEIKKLKDIPIILLTSLSEPENVINGLVCGATNFIV
KPFDEQFLLSRIKYILINKEMRDSAFSQMGIEIFFRDK--------------------------------------------------------------
-----KYFISSERVQMIDLLLSTYEVAIDL---------------------------------------KKANQELEQIKDELERRVLERTA--------
----ELSKSQLQKEIEERKHVEALRQSENKLA-IKNQISQVFITASDDQVVLKALKSEYGIYGYTDES--GSYTCSSVTSEVKKECWAGISGNAVSGKEN
EPPEGHIQITRILNVPIIHRGNVIGGHLAPLLNAKERKMLEAQQRTLAGGIAHDFNNILFPIVGHTEMLLEDVPEGSLWRDDLNEIYIGALRARDLVKQI
LTFSRQES----IELILTKTQPIIKEVLKLIRSTIP------TTIEIKQNIETDCGLVKADPTQIHQIMMNLTTNAYHAMQDGGELKVSLKEVGTYACLT
VADTGIGMDKNITEKIFDPFFTT-KE-----KGTGMGLSVVHGIVNRMGGTIRVHSEPGKGSEFNVYFPVA--------------
>tr|I4CDL6|I4CDL6_DESTA PAS domain S-box OX=706587 OS=Desulfomonile tiedjei (strain ATCC 49306 / DSM 6799 / DCB-1). GN= PE=4 SV=1
-GEILIVEDSAMQAKRLKRLLEEYRYSVLVAHDGEEGLAMALEHVPTLIVSDIIMPKMDGYRMCRAIKSIQNIPIILLTSLSSPEDVFLGLESGADCYVC
KPYDGRTLLSRIESVLTTMAKRPPSKPEEELEIFLGSK--------------------------------------------------------------
-----KYLIKSSRDQILNLLLSTYQDAVIL---------------------------------------REMRTKLVMVNEELEKLVAERTE--------
----AL-----KREIEERKQIEALASEKERLWVTLRTINDGVITTDTRGKVILMNRAAEELTGWTQEEAIGTGVCNLIKTETRETG---LKSGGLFGVGQ
ITKGGTEKIVDVNGTPILDKTNKIIGVVLVLRDVTENKRIEEEQKVLAGGIAHDFNNLLTAILGNVSLAMYADHQEK-VIPRLDEAEKASLRAKDLTQQL
LTFAKGGA----PVKKTASIADVLKDSVKFLRGS---------NVRCVFDVAKSLWPVEIDEGQISQVVHNLIINACQAMPSGGTILVQAENTGKYVKLS
VRDEGHGIPSDILTKIFDPYFTT-KK-----RGSGLGLATSYSILKNHDGLLTVESEIGRGTTFFIHLPVS--------------
>tr|A1ASD6|A1ASD6_PELPD Histidine kinase OX=338966 OS=Pelobacter propionicus (strain DSM 2379). GN= PE=4 SV=1
-MNILIVEDNPNEREILRFTLERHGCMVIEAADGLEGLDLAIHRQPDIIVSNTLMPRMDGFQLLWALKKLTSIPFLFYSDTFGEQEEKLAISLGAAAFIV
KNKAPESVWLQADAAITATSKPQKTIVYPT----------------------------------------------------------------------
-------------IDKSDRKHLREYGRIKL---------------------------------------EEKVRELQAALTERRQVVDEIK---------
----TLKS-ELAIRASEFKRAETIKEQEQQLSNFFEVAPFPLLLLDGELRIRRINKHGCSLTGIDMLGLRSALRCIHFGPNCRECLKNCLNSEQQYSCKS
LPKDSE-TNLTFILSISRATTGKQDMLLITLQDITAQKTLERKQKILAGGIAHECNSHLSTIVGYGNTTLMSMSRNDPNRQNVEQIVTNAKKAAHLTNKL
KIFCRKQS----GEKKNINLNETILSMQNNLLRLFG------QDINCTTLISDQELTVCADKHHLELLLTCLINKILDTTQRGGSLTITTDQTNSYALLT
VTHSNASMGSDDLEHIFNPLFSI-QE---QSKWPELQLSLISHIIKQHESHITVFSEPGKGTAFRIYIPLV--------------
>tr|A7H7Q7|A7H7Q7_ANADF Multi-sensor hybrid histidine kinase OX=404589 OS=Anaeromyxobacter sp. (strain Fw109-5). GN= PE=4 SV=1
--DVLAVDDDPRNLEATRALLSGSGARIVEARSAEEALRILLTREVALILLDVGLPGMSGLEMAKLVRATRHTPIIILTASSDPRLLERGYALGAVDFLT
TPVPEQALRAKVAFFIEAHRK-------------NEALRHN----------------AELLRAAQERELARNAL-------RREM---------ERDRRL
VDTLHERLKSSVRSRERLPA--ICDRV-AAHL-GSL-----------------------------------------HLADPDGRLSLAAT---------
GGADGAQRALDSVEAILGG-------TAARVAARGEPV--GVV------------CCAARPL-HTGD----RV----------LAAFAFG-SAERDCDPD
DPATLELVGY---AAMALERDR--------L--IAELREADRRKDQFLAMLAHELRNPLAPVTNAVRLL-QDYGADAVRERALAAAERQVRHMARLVDDL
LEVSRVRSGKVCLRKETVELARVVREAVQSVDELVA-----SRGHALALELPDAPLLVEGDAVRLTQVVENLLTNAVKYTDPGGHLRVELRREGREAVLA
VRDDGIGIAPELQDTIFELFVQAEQGVDRSRGGLGIGLSLVKTLVDMHGGAVGVTSAPGQGSTFTVRLPAL--------------
>tr|K9TMG7|K9TMG7_9CYAN PAS domain S-box OX=56110 OS=Oscillatoria acuminata PCC 6304. GN=Oscil6304_4074 PE=4 SV=1
MAKILIVDDDVTVQLVLQDLLESDGHRITVASDGTEGLRLARELEPDLIVCDWMMPGLDGLEVCQKIKADSPMFFILLTAREEVGDRIKGLNTGADDFLS
KPIETEEFLARVRAALRLH-------------GLTQELSQANQQLEALVEVQRRLLAKGDTTSPYTEILKPLAAHASRVYLCSPLLVAQWNCE---ELKI
QDSNPQPAQCLS---LKAPI--LIERWVSLLARGEVIADVVSNFPDSERELLEQLLILPLIVHFGFIRFDNCEPRVW-------------------SESE
VSILQAAAAAVSLHKERALAEVALRSSEARYRAIVEDQTELICRFAPDGTLTFVNDAYCRYFGVSRKELMDGSVVSLIPDIDRNPVARAIFDAQGVLEFQ
ITEDGSIRWIRDGFPI-RDEEGKIYRIAGISEDITEIKRAEEFRTRFVSMVSHEFRTPMTTILSSADLLLEEWPNDKKKFQALHRIQSATVNMTQLLEDV
LFIGRAEMSQLPFNPQSLDLVPFCKGIVEEFQFSS------TKNYTINFVLSRKSRKPCFDEKLLRYILNNLLSNAIKYSPEGGEVYFELTCTDTDVTFM
IKDSGIGIPSEEIPRLFQTFHRCGNV--GNIPGTGLGLAMVKRSTDLHGGEISVKSEVGFGTAFTVRLPL---------------
>tr|K9TMI0|K9TMI0_9CYAN PAS domain S-box OX=56110 OS=Oscillatoria acuminata PCC 6304. GN=Oscil6304_4222 PE=4 SV=1
MSKILVIDDDGVTRLLLKRNLQMQGYDVTLAKNGAEGLRLAKELRPDLIVCDWMMPLVDGVEVCRHIKADPTTFFILLTVRGQVDDRIQGLDSGADEFLS
KPIESDELLARVRAGLRLH-------------QLTQQLRQANQQLLALVEVQQQLLSAVDSTSSYIQLLAPLAAQASRAYMSEPRVLCEW-FA---KVPT
DQQNSQAIQGLI---PPKP---LPSRWIATFKKGGIVAGKVSDFPEAEREILEQLLMVPLTLKVGFIGFENCIAEL---------------------DSL
LPILRAAAAAICLHRDRSAAVLALRASEARYRAIIEDQTEFICRFAPDGTLTFVNDAYCRYFTMTREELMDGSLVPFRPDFERDFVNRAVFSGDELVEFQ
ITE-----------------------------------QAEQLKTHFVSMVSHEFRTPLTTILSSADLLQEDFPDSKKKLQAIQRIQSVSVNMTQMIDDI
LLIGHAESGNLKCTCNPLELVQFCNQLVEDMQFID------NGLHGIELILSQPSLSACMDEKLLRHILTNLLSNALKYSPAGMPVQLELGDRQNLAIFH
IKDRGIGIPPKDLPHLFEPFHRCRNV--GTISGTGMGLAIVKKCVEIHGGDISVQSEERDGTTLTVILPR---------------
>tr|A5G434|A5G434_GEOUR PAS/PAC sensor hybrid histidine kinase OX=351605 OS=Geobacter uraniireducens (strain Rf4) (Geobacter uraniumreducens). GN= PE=4 SV=1
--RVLIIDDSPDDARLIVRELQHE-FDPVVTSEEM--KSALNAENWDVVISDYVMPQFSGLSALKLLHQLIDLPFIMVSGQMGEEVAVESMRAGARDYLI
KD--N---LTRLIPAIK------RELKEAFVRNE------------------------------------------------------------------
--------RRKAEKALHATEARFQSLVEQSLVGIYLLQDGIFSYVNPKFARIFGYQQNELIESKTLLDIESYLNLLGENAQSLHFNFQGKRKYAKIIDLE
AHGAKTELNGKPAVIGTLLDITERKRAEEELRKLVEQSPVSVVITDTEGNIEYVNPKFTAVSGYNEQELLGKNPRILQAGTMKADEYKQMWETITAGKEE
HNKNGELFWESASISAIKNTEGQITHYVGVKEDITERKKLRQAQKMLAGGIAHDFNNLLTIINGYSTLLLRSLGIDSPQHKEAEQILRAGERAADLTRQL
LSFSR----KQILAPKVLNINTQVKNIEKMLCRLIG------EHITLVTNMDPDVGLIKIDPGQVEQIIMNLAVNARDASEDGGRIVIETANPGSYIMLS
VCDNGMGMSEDVKRRLFEPFFTT-K----ELGGTGLGLATVYGIVKQSGGYIDITSELEQGATFKIFLPRV--------------
>tr|I2IX38|I2IX38_9BURK PAS domain S-box OX=243261 OS=Burkholderia sp. Ch1-1. GN=BCh11DRAFT_03105 PE=4 SV=1
-ARLLVVDDNADLREYMSRILRA-AHDVRLATDGQAALEAARQERPDLVLSDVMMPRLDGFGLLRALRALRDTPVLMLSARAGEEARVDGIEHGADDYLT
KPFSARELLARVSGNLQLARLRRETETKLREESRTLEILNRVGSTVAAELDLNRAVQIVTDAATELTGAAFGSFFYNVLDDKGGSYMLYTLSGVPKETFE
QFPMPRNTAVFAPTFDPRYGHNAPHRGMPEGHLKVRSYLAAPVQSRSGEVVGGLFFGHPEPGVFTERAERIVAGIAAQAAIAIDNARLYRAAQTEIAERT
KAQSALRDLNETLER-RVIETVADRDRL-W-----ELSEDLLVVADIEGRLQRVSPSWSNALGHNTHWLMSRSYVDLVHPDDVEVVRTHLRRTGVPVRYE
FRRDGTWRWVAWTLAL-DP-DTA--RIHGVGRDVTADKETTKMEAKLTGGVAHDFNNLLQVIGGNLQLLAKDVAGSEKPEQRVRNALAGVARGANLASQL
LAFGRLAPK-------VVNLGRFVRGLDDMLRRALG------DGVEETIVSGG-LWNTLVDPFQVENALLNLAINARDAMNGHGKLTIEAGNAGQYVMLA
VTDTGAGMPPEVRERVFEPFFTTKP----EGQGTGLGLSMVYGFVKQSGGHVKIYSEEGHGTTIRIYLPRV--------------
>tr|J3AUK1|J3AUK1_9BURK PAS domain S-box OX=1144309 OS=Burkholderia sp. BT03. GN= PE=4 SV=1
-GKLLVVDDNADLRDYMRRILSA-AHDVHVAGDGEEALASARNLQPDLIVSDVMMPKLDGFGLLRELRALRETPVLLLSARAGEEAKVGGLESGADDYLI
KPFAARELLARVAGNLQLARLRRETGNRLREESRTLEILNRVGTAVAAELDLNRAVQVVVDAATELTGAAFGSFFYNVQDDKGGSYMLYTLSGVPKDTFA
KFPMPRNTAVFAPTFDTRYGHNPPHRGMPEGHLKVRSYLAAPVVSRTGEVLGGLFFGHPTPGVFTARAERLVEGIAAQAATAIDNARLYQAAQREITERT
KAEEALRELNETLEA-RVIEAVADRDRL-W-----DFSEDLLVVAGFNGELQRISPSWTRVLGHDAHWLALQSYFSLIHTDDHSMVKAHLRRTGAPMRFE
LRHDGSWRWIAWTLSL-DP-DTK--RIHGVGRDVTSDRETQKMEAKLTGGVAHDFNNLLQVIGGNLQLLADDVIGQERSAQRVRNALGGVARGAKLASQL
LAFGRLAPK-------VVNLGRFVRGLDDMLRRALG------DGIEETIVSGG-LWNTLVDPFQVENALLNLAINARDAMDGHGKLTIEAGNAGQYVMVA
VTDTGSGMSADVQEHVFEPFFTTKP----EGQGTGLGLSMVYGFVKQSGGHVKIYSEMGHGTTIRLYLPRV--------------
>tr|K8REU9|K8REU9_9BURK GAF sensor hybrid histidine kinase OX=406819 OS=Burkholderia sp. SJ98. GN=BURK_016585 PE=4 SV=1
-GRVLIVDDNADLRDYMRRMLIA-AHDVNVAADGEAALAIARDVRPEVIVSDVMMPRLDGFALVRALRELRETPVVLLSARAGEEARVDGLEAGADDYLT
KPFSARELLARVASNLRLARLRRATEQKLRDESRTLEILNRVGTAVAGELDLSRAVQVVVDAATELTGAAFGSFFYNVLDDKGGSYTLYTLSGVPKDTFA
KFPMPRNTAVFGPTFDPRYGHNAPHHGMPKGHLAVCSYLAAPVLSRTGEVLGGLFFGHPEPGVFTERSERILTGIASQAAIAIDNARLFQAAQDEIAQRT
KAQDALRDLNETLER-RVADAVADRDRL-W-----ELSEDLFFVASFEGALLRVSPSWTTVLGFDSQRLHSHTVMDLLHPDDAPAAAEELRANGLPVRYE
MNRDGGWRWIAWTVSL-DP-ATR--RIHGVGRDVTSDRETAKMEAKLTGGVAHDFNNLLQVIGGNLQLLAKDVAGQDKPEQRVRSALAGVARGANLASQL
LAFGRLAPK-------VVNLGRFVRGLDDMFRRALG------DGIEETIVSGG-LWNTLVDPFQVENALLNLAINARDAMNGHGKLTIEAGNAGQYVMVA
VTDTGSGMSPEVQERAFEPFFTTKR----EGQGTGLGLSMVYGFVKQSGGHVKVYSEQGHGTTVRIYLPRA--------------
>tr|Q13AI6|Q13AI6_RHOPS PAS/PAC sensor hybrid histidine kinase OX=316057 OS=Rhodopseudomonas palustris (strain BisB5). GN= PE=4 SV=1
-PRVLLADDNPDMRDYVARLLGE-SYEVDAVGDGVAALEAAWKQRPDLVISDIMMPRLDGLSLLKALRNLADVPVIFLSARAGEEARVEGLEAGADDYLS
KPFSARELLARVRSNLDIAEVRREALRTEHALRQEAQAARERAEGILASISDGFIALDGDFRFTYVNAAAERLMRRPAAELLGKKYWEV-----------
-----------------------------------------YPAMAGTMIERSYRSAMTDRIGAEFESYHPPSKRWFHLRVSPTNGQSISVYFRDITDRK
RAVAALRELNDQLEEERTAELRQKEARL-RTI--FAASYTYQALLALDGTLIDANLTSLSGIDAKLEDIVGKPLWETPWIVGTPGMSEMIVAAGETVRRE
INLVGGWRWFDFMRPV-HD-AQG--QVIAIAVEITERRKAEKMEAQLTGGVAHDFNNLLTVIRSSADLLRRRELPPDRMRRYVDAISDTADRAAKLTGQL
LTFARQNRQ-------VFDAAHQIEQIAEMLKTALG------SRASFALTVAERPLAVEADANQFDAALVNLVANARDAMDGQGALEIRVAR-EGVVAVS
IADTGSGIPPDKIDRIFEPFFTTKE----IGRGTGLGLSQVYGFAKQSGGNVTVDSEVGAGTTITLRLPLS--------------
>tr|Q2ITE8|Q2ITE8_RHOP2 PAS/PAC sensor hybrid histidine kinase OX=316058 OS=Rhodopseudomonas palustris (strain HaA2). GN= PE=4 SV=1
-PRILLADDNPDMRDYVTRLLGE-SYEVETVGDGVAALEAAWKHRPDLVISDIMMPRLDGLSLLKALRSLADVPVIFLSARAGEEARVEGLEAGADDYLS
KPFSARELLARVRSNLDIAEVRREALRTEHALRQESQAARQRAEGILASISDGFIALDADYRFTYVNAAAERMMRRSASDLIGKVAAEA-----------
-----------------------------------------YPAVVGSRIEDSLRRALTQRIGSEFEIEHPSSDRWFHLRVAPTNGESVSVYFRDITERK
RTETALRDLNDRLEEQRTAELRQKEARL-RTI--FAASYTYQALLDVDGAVIDANLTSLSGIGARLEDVVGQPLWDTPWFAGTPGMQQTIVAAGQSVRRE
LDLVGGWRWFDFMRPV-HD-AQG--QIIAIAVEITERRKAEKMEAQLTGGVAHDFNNLLTVIRSSADLLRRRELPPERMRRYVDAISDTADRAAKLTGQL
LTFARQNRQ-------VFDAAGQIEQTAEMLRTALG------SRASFALKIDQRPLAVEADANQFDAAMVNLVANARDAMDGQGALEIRVAA-MDVVAVS
IADTGAGIPQDQIDRIFEPFFTTKD----VGRGTGLGLSQVYGFVKQSGGNVTVESALGCGTTITLRLPLS--------------
>tr|B3QIZ6|B3QIZ6_RHOPT PAS/PAC sensor hybrid histidine kinase OX=395960 OS=Rhodopseudomonas palustris (strain TIE-1). GN= PE=4 SV=1
-PHILLADDNHDMRDYVARLLGD-AYEVEAVGDGVAALEAVKKRRPDLVLSDVMMPRLDGLGLLKALRSVADLPVIFLSARAGEEAKLEGLEAGADDYLS
KPFSARELLTRVRANLDTAAIRRTALRTEYALRQEAQAARQHAEGILASISDGFIALDEQYRFTYVNAAAERLIASTAGELIGKVYWDV-----------
-----------------------------------------YPMMLGTKIEQAYRRAMTERVACEFESYHPPSKRWFELRVAPTNGKSISVYFRDITEQK
KAEAALRDINEQLEEERTAELQQKEARL-RTI--FAASYTYQALLDVDGVVLDANRTSLAGIGGQLEDVIGKPVWATPWFGSTPGLPEMIVAAGETVRRE
VNLAGGWRWFDLMRPV-QD-PQG--QVIAIAVDITERRKAEKMEAQLTGGVAHDFNNMLTVIRSSADLLRRRELPPERVRRYVDAISDTADRAAKLTGQL
LTFARQNRE-------VFDAAEHIEDVSDMLKTALG------SRAVFNLDIAERPLPVEADTNQFDAALVNLVANARDAMDGHGTLTVSVTR-RGFVEVS
IADTGCGIPREQIERIFEPFFTTKD----IGRGTGLGLSQVYGFVQQSGGTINVDSAIGCGTTITLRLPLS--------------
>tr|F4QLI5|F4QLI5_9CAUL Sensory box protein OX=715226 OS=Asticcacaulis biprosthecum C19. GN=ABI_19230 PE=4 SV=1
-PRVVLADDNADMRDYIHRLLND-DFDVVAVTDGEQAWQAIRDQLPELVLTDVMMPKLDGFGLLERLRGTRRLPVIMLSARAGEEARVEALDAGVDDYLV
KPFNARELLAKVRSQLQIAHLRREGEAQVRRVLESIRDGIMVIERDWRITYMNGAGRDIIAGRGVDPEAIIGLSHWD-----------------------
-----------------------------------------------------AFPHAAGTFVEDHLRRAMEDRVMVEFENFYAPWQRWFAVRVYPVDEG
GVSIYFHDITDRKE--ADAALRISQERW-HGL--AESMPQLVWIAGQDAGVSYLNEQWAIYTGRPIGELINEGWVDNLHPDDRQPMFDTWVAAEGLYDIE
LRRDGGYRWFKTGVPV-RE-ASG--RLNGWCTDIQDMVEARRAKSEFLANMSHEIRTPLNAIVGLTHIMLNYKTDPASHGKYLQTMKDSADTLMQLINDV
LDLARIEAD-------RVELEMAPCPLHEVVRECLG------ITEVLDFGLPHGTV-VETDVLRLKQILMNLLSNAVK-FTQTGRIDVEVSA-LLPVTIR
VRDTGVGIAADKIEHIFAQFTQTRR----FG-GSGLGLAISRRLSEMLGGRLTVESEVGKGTVFSLSLALK--------------
>tr|H8N0G6|H8N0G6_CORCM Sensory box histidine kinase/response regulator OX=1144275 OS=/ M2) (Myxococcus coralloides). GN= PE=4 SV=1
-GHVLMADDNADMRDYVRRSLEG-RFTVETVADGAAALAVVRERPPDVVLSDVMMPGLDGFGLLRALKSTASVPVILLSARAGEEAKVEGLNAGADDYLV
KPFGVRELVARLEGTVNAARGRAQREELLKALKLSEMRYRLATRATKDAVWDLDLSTQQLTWSEGIYTLFGYAPGTVSPGLDWW----------------
-----------------------------------------------TDAVHPEDRAHAIESLHAAAEAPEGSDWRAEYRFRKADGTYAQVEDRGWVVRD
AAGTALRMVGAMQDVAAEDALRRSEEEF-RTL--AEALPEAVFVTAPDGSVTYVNGVLTEQTGVSAETLLDRGYRQVIHPDDLPSSGRAWLKHGDRYQAE
VRYDGLYRWHLVAMSV-RD-AEG--RIIKWSMDVHELRQAQRADFQLIGIVSHDLRNPVSAILLGAASLMRREELDERSTKAVSRIQSAAERAHRMIRDL
LDFTQRLGG-------GLHIQRRASDLHEIVDGVLE------EIEAPDREIRRRRSGSGLDPDRLGQLAQNLVTNALKYSPRDTAVRVE----AGTVTLS
IHNEGAPIPPERMGRLFEPLQRVDH----SSRSIGLGLYIVKQLVEAHGGIITVESTAEAGTTFTVRLPVP--------------
>tr|D0LZ52|D0LZ52_HALO1 Response regulator receiver modulated diguanylate cyclase with PAS/PAC sensor OX=502025 OS=Haliangium ochraceum (strain DSM 14365 / JCM 11303 / SMP-2). GN= PE=4 SV=1
--KIVAIVDEPALAEEVRGEL-SRQYDL--ITTEGARAR--ANPDIDVVL----S---------------RDVPILVVSADPESSDLNTAIHGQIAGAVQ
VPWRSGELSMAVERTLRRLDALSIMNELASADS-THDQ---RLR---VAFLTIDNGYAG------FLHLHCHQPHGALRTARDRCMEIF---------RS
L--TGR----------IIEEDKLTVDISGDR---------EGSFSHVPIYV--EGAVVGIILA----G----TTPAKQL-------TA------------
DEDKLMFFLAARAAEAMKRLSAQRDNERRKLSLMIEAMADGLIYAYASNNRVLINPAARQMLGIDAEPVTTQFLKEKLGFY-PFDLVAARKQGPSESVRE
VRVGTRSFHS--IVSPVRDRSGKLLGVVVVLRDMTEAKELARRQSEFVSVVSHELRTPLTSITGALDIVLSGYSGRVKQQRYLKMARESCAVLNALVDDL
LDTANADDGDMPVHLRPLVVDDLALEVMDRYHEEAE-----TKRIEIRLEREEENVRIVGDGDRLSQVLTNLLSNAVKFTTVQGQVSIDIFGKDAFVCIS
VYNSGKPIPRAASERVFDKFEQLDDVTTRKVGGTGLGLPISRAIIEAHGGRIWLESL-PTGTRFVFTLPITPD------------
>tr|H8MHX2|H8MHX2_CORCM Sensory box histidine kinase/response regulator OX=1144275 OS=/ M2) (Myxococcus coralloides). GN= PE=4 SV=1
-HTLLFVDDEADVLDILSRMF-QRRYRVLTAPHGKAALEILRTESVDVLVTDQRMPEMTGIDLVNAARAEGDVTTLLLTAYTDPQDIIAAINQGVYRYVT
KPWDVNDLLITVKNALQRVEALFVLYEVSRASANDPA-SYDALRVLPAALIAPDGQRGA------TLRLRCVGNEEALLGVKESMLGAY---------RK
S--SGL----------PLPEDRVITRVTGTTTKDSASPVVYPNQLTVNLTA--AGKPVGMLSL----F----SHRADAF-------TE------------
DDGLLLDVLANQTADAIQSLRSAEEEARHRMERMVASMADGVVLTDEKNDIVVMNPAARRILHAGEEGPSNRLLEERLGFQ-PFQLVRNLEYSGHQVLRE
VKLFDRTVQT--TVTPVNDARGTLRGVCVVLRDITDQKRLEERKDTFVSMVSHELRTPLTSITGALDLVLNRMAGDIRQHRYLSLAKDSAEKLNSIVDDL
LDLSKYAQGRLKMSFERIYLEELVQRVVEKYGPAFA-----EKRIRVVPLLPQHPLRAMVDPNRVNQVLNNLLNNAVKFTPEGGEVRVELRATPGYVVLS
CWNSGDPIPEESLERIFDRFEQARTQANRTVRGTGLGLPICRNIVEAHGGRIWSEPS-HTGVRFIAVLPTEPP------------
>tr|A7HBG1|A7HBG1_ANADF Histidine kinase OX=404589 OS=Anaeromyxobacter sp. (strain Fw109-5). GN= PE=4 SV=1
-HVILFVDDEPEVLGLLRRTFSQDGYEALTAGGAEEALRILAEREVDLLVTDQRMPGMTGVELIAEARRRRDLCAILLTAYTEPEELVDAINRGVYRYLV
KPWESADLRQTVVRALRRLQTLEVAAEVAR-DASTAE-SHTRVRVVPAALFAPAGT-AP------VLLLRPVARDSALLQVKEDALAAY---------AE
H--AGN----------RLAESTLQIRVLGSAGRAST----FGSRLAVPLQV--DGVTAGVVLL----Q----SMATGAF-------GP------------
GDARVLDVFVNELGAALRAFGAKHAGERHRLERVVECMADGLLFAATGSDEVIANPAARRMLGAALDPLPVRWLKDALGFY-PFDLVRGIEPSGRAFVQE
VHLLDRTLSS--IVSPVAEADGRLAGVAIALRDVTEQKRLEERKEEFVQVMSHELRSPLTSVTGALDLVLSGLAGQLKQARYLRMARESTEKLNGLVDDL
LDLARLAKGKLQMEPEVTSLDELVRATVERYQPAAA-----ERGQEVAVETPPASVRMVADPARVGQVLSNLLTNAIKFAPENSVIRVRLFRSPGMLGLS
VWNAGEAISEPDLERIFEKFEQARSDRNRRVRGTGLGLSICRGIVEAHGGAIWAESP-GDGVRFVVVLPEEAP------------
>tr|Q1D407|Q1D407_MYXXD Sensory box histidine kinase/response regulator OX=246197 OS=Myxococcus xanthus (strain DK 1622). GN= PE=4 SV=1
-HTLLFVDDEADVLDILTRMF-QRRYRVLTARSGSAALEILRKEPVDVLITDQRMPEMTGIELVATARAEGDVTALLLTGYTHPDDIIAAINQGVYRYIT
KPWDVNDLLITVKNALQRVEALFVLYEVSRASANDPA-SYDNLRVLPAALIAPDEARSA------TLRLRCQGMEKALLGVKESMLGAY---------RK
S--SGL----------LLPEDRVITRVAGTTTQDAAAPSVYPSQLTVNLVA--GGRPVGMLSL----F----SQKPDAF-------SE------------
DDGVLLDVLANQTADAIQSLRSAEEEARHRMERMVESMADGVVLTDEKNDIVVMNPAARRLLHAGENEQTTRLMEERLGFQ-PFHLVRGWEYGGGQVLRE
VKLFDRHVQT--TVTPVTDARNTLRGVCVVLRDITEQKRLEERKDEFVSMVSHELRTPLTSISGALDLVLNFMAGDIRQRRYLSLARDSTEKLNAIVDDL
LDLSKFAKGRLRMNFEVSYLDELVQRVVEKYGPAFG-----EKRVLVKPVLPRHPLRVLADPNRLDQVLNNLLNNAVKFTPEGGEVRVEIHATPGYVVVS
CWNSGDPISEESLERIFDRFEQARTKANRTVRGTGLGLAICRNIVEAHGGRIWCEPC-TDGVRFMVVLPTEPP------------
>tr|E3FCT1|E3FCT1_STIAD Sensor protein OX=378806 OS=Stigmatella aurantiaca (strain DW4/3-1). GN= PE=4 SV=1
------------MLDILVRMF-QRQYRVLTATSGQEALSILRTQTVDVLVTDQRMPEMTGIELVAAARAEGDVTALLLTGYTDPEDIIAAINQGVYRYIT
KPWEVNDLLITVKNALQRVEALFVLYEVSRASASDPP-SYEALRVLPAALIAPDDSRSA------ILRLRCLGTEKALLGVKESMLGAY---------RR
S--SGQ----------LLPEDRLTTRVTGTISQDASAPAVYPSQLTVSLVA--GGRPVGMLSL----F----SQRLQAF-------TE------------
DDGVLLDTLANQTADAIQSLRAVEEEARRRIERMVEAMADGVLLTDEQNAIVVINPAARRLLRVTEEALTGQMLEERLGFQ-PSELIRGWEYSGSQMLQE
VELFDRHIQC--TVTPVNDARGTLKGVCVVLRDVTEQKMLEERKDEFVSMVSHELRTPLTSISGALDLVLNFLAGDIKQQRYLFMARESTEKLNSLVDDL
LDLAKFAKGRLRMNFELTYLDELVRRAAEKYGPAFQ-----ERRVKVLMTLPQHGLRVLADPSRVNQVLNNLLTNAVKFTPEGGEVRLELKATPGHVALS
CWNSGEPIAEESLERIFDRFEQARTPSNRTVRGTGLGLAICRHIVEAHGGHIWCEPS-TEGVRFVTVMPVEPP------------
>tr|K7VVX2|K7VVX2_9NOST Two-component hybrid sensor and regulator OX=46234 OS=Anabaena sp. 90. GN=ANA_C10122 PE=4 SV=1
--QILFLEDSPVDRVLYSRFLTLATYEITEAKSGLEGLTKLAESQPDLILLDHQLQDMNGLEFLNQLQLSPHIPVIILTGTGDEKIAVQAMKNGVQDYIV
KDKITPQGLCRAI-----HEVLE------KAE-----L-YQDLQKLNASLEKK-----VQKLTEELAVYRAIFNQRTGLLDLEG------MVLELNQA-S
LEFTGL----QMADLINRPIWEVY--G---WQISQATQDQLKHAIAR-----------AAQFI-----SSQ---------VEVQGIDNQILTIDFSIGPL
RNNAGLISEGRDITEAKLNE-AKCKQAEATLKFQAQILEEIVITTDINGIIQSWNLGAENYYGYTAAEMIGQS-VSILYLDPVELQTNIMSTLLAKGRHE
VEKSGDIVYINLRLSVIRDNHGNITHIVGCSHDITKQQAAIKERDEFLAVVSHELRTPLNSILGWASLLKKGKLKPEETDEALSIIERNAKLQVYLINDL
LDMSRIFQGKGTMKVSSVNLATIISAVSETLFLAPK-----TKKIQIQTIIAANIGLVAGDPVRLQQIVWNLLSNAVKFTPHGGQIEVRLECVGFDAQIT
VSDTGKGISPEFLPYIFDYFRQEDSS--TTFGGLGLGLAIARNLAELHGGTIQADSSLGQGATFTFRLPL---------------
>tr|G6FUI7|G6FUI7_9CYAN Multi-sensor signal transduction histidine kinase OX=741277 OS=Fischerella sp. JSC-11. GN=FJSC11DRAFT_2534 PE=4 SV=1
--IILIIDDCSEDRAVYRRYLSQHHYVILEEETGESALKLCQQLQPDSILLDFLLPDMDGLEFLTELKQGSMPAVIMLTGHGNENVAVQAMKSGVQDYLV
KGDITAESLRFTI-----QSAIE------NVQ-----L-RQQLQRSEERFRTS-----VENMLDCFGVYSAIRNQAGEILDFR--------IDYLNAA-A
CESNLM----IKEEQLGKSLCELF--P---GQRKYGLFEEYCQVVNT-----------GKPFV-----KES---------LIYTDIGKQQFTRAFDIRVA
KLGDGFVASWRDVTKKKQIE-QALRESEERYRFLSEAIPQIVWICDANGECEYLNQRWYEFTGQAVEQGIGSGWLEVVHPEDTQRVMQAFTQSLNTGKYE
VEHDQTYHWFLARALPKKDGQGRIVKWFGTSTDINDRKQLEAERDEFVAMISHDLRSPLNAILGWAKLLQSRKQDEATIIRALQTIERNALSQAKLIDDL
LNMSRILRGQLDLQLCQVNLVTIIQTALETVYPSAD-----DKSICLESKLDDAVPPIVGDPHRLQQILGNVLSNAIKFTPEGGRVEVRLERVAFYVQIT
VTDTGIGINPNFLPHIFERYRQVESY--KE-GGLGLGLAIARHLVELHGGTIEAKSEEGKGATFTILLPF---------------
>tr|B5ZJ20|B5ZJ20_GLUDA Response regulator receiver sensor signal transduction histidine kinase OX=272568 OS=PAl5). GN= PE=4 SV=1
-PALLLVEDSDTQALRIRRMLESHGFAVTRVASGEAALDSLDGRIPDLVVADYHLPGMNGGQMARQLRMSAVIPVLMLTEGGEPGLEREGLESGADAYVP
KSADPDLIVFRIRALLREGAGALLRDGA-GARD----GMFRRARILIVGG--------DGTRDRDVTSLAALMRSDGHEVQPMSMDRQDWFEAAPD-CVV
VDLVS-------------DAF----DGIAF-CRELDDVRQEVVVAGGV---PPRIL--GLS-G--GQALRGV-FSARAFEAGVDDLVADD----------
VEPDVLALRIRALVRRARRVDQERQAREIAVE--------------TARAE---AASIASKASLA----------EA------------LEQANAE----
--LAD------ANRKLIETQ--------------GKLIQTAKMASELVAGIAHEINNPLAFILAHKDTVARLERDAAKCRDRVESMNLGLRRIQNLVLNL
RKFSRLEEGQFQ----VIDVPEALETVLALLGQKFG------SEIVVERDYRAP-DRLYCQSALLNQVLMNIISNAADAIPARGMIRIGTELRDGEYVFT
VMDNGPGIPPDLKERIFEPFFTTKPVGA----GTGLGLAIAYGVVQAHRGTISITDAPAGGTVFTVSVPWQ--------------
>tr|D5QH09|D5QH09_GLUHA Response regulator receiver sensor signal transduction histidine kinase OX=714995 OS=Gluconacetobacter hansenii ATCC 23769. GN=GXY_12483 PE=4 SV=1
-PAVLLVEDSDTQALRIRHMLQGHGFSVERVASGEAALDTLDSHIPDLVIADYHLPGMNGGQLARQLRMNAVIPVLILTEGIEPGLEREGLESGADAYVP
KSSDSALIVFRIRALLREYAG---NVRA-R-PG----RVFRRARILVVTPR-----HDATTDGGRVGALIDLLQRDGHIVDPAHFDRQMLLDPEPD-CVV
VDLTV-------------GGM----DGVVF-CRRLDELRQEVLMRGGV---PLRIL--AIS-P--PSPDQRE-FSARVFETGVDDLVPDD----------
VAPSVLALRIRVLVRRVRRIEVERQNREIAVK--------------SARAE---AAAIASKASLA----------EA------------LEQANRE----
--LAD------ANRKLIETQ--------------GKLVQTAKMASELVAGIAHEINNPLAFILAHKDTVARGESSTAKCRDRVASMNLGLRRIQNLVLNL
RKFSRLDEGLFQ----VIDVPEALETVLALLTQKLG------NGIAVHRDYTAP-ERLYCQAALLNQVIMNIISNAADAIPAQGRIDIRTELRREGYVFT
ISDTGPGIAPDVQERIFEPFFTTKPVGA----GTGLGLAIAYGVVQAHQGTLMVTNREQGGAQFTISVPWR--------------
>tr|G2I5H2|G2I5H2_GLUXN Two component sensor histidine kinase OX=634177 OS=Gluconacetobacter xylinus (strain NBRC 3288 / BCRC 11682 / LMG 1693). GN= PE=4 SV=1
-ADLLLVEDSDTQALRIRRMLEGHGFHVHRVASGEEALDTLDARLPGLVIADYHLPGMNGGQLARQLRMNAVIPVLILTEGIEPGLEREGLESGADAYIP
KSSDPTLIVFRIRALLREHAA---HAPS-PVAE----HMFRRARIMVIAP--------ASPRLQAVPELIGQLRRDGHIVDPAELDPTLLHDPEPD-CIV
IDLAC-------------REF----DGLEV-CRVLDEWRQADLLSGNV---PLRLL--GVDGG--PRPDARE-FSARMFESGIDDLVSRD----------
VGPAALALRIRVLVRRVRRIEVERQAREIAVK--------------SARAE---AAAIASKASLA----------EA------------LEQANRE----
--LAD------ANRKLIETQ--------------GKLVQTAKMASELVAGIAHEINNPLAFILAHKDTVARGATCTAKCRDRVGSMNMGLRRIQNLVLNL
RKFSRLDEGVFQ----LIDVPEALETVMALLTQKLG------SGIVVRRQYEAP-ERLYCQAALLNQVIMNIISNAADAIIAEGEISIHTFLSHNAYVFV
ITDNGPGIAPDVQERIFEPFFTTKPVGA----GTGLGLAIAYSVVQAHHGSLQVGSVPGGGARFTISVPWH--------------
>tr|C7KQ89|C7KQ89_ACEPA Two component sensor histidine kinase OX=634457 OS=Acetobacter pasteurianus IFO 3283-32. GN=APA32_10210 PE=4 SV=1
-D-ILFAGVDAAWQAHLETLLQARGLRVKSVADGRSAFAGFDEDLPDLLVVPARLPDMPATQLCQRLRLNAAIPVVVLLPEANSRQEAEILERGADCCFS
MADNPLLLVFRICALLREYDE----DLA-GREG----VVFRQPRIVIMTA-------PGGADFEPIRYLVELLQQNGEDADPEKLDLSGIASSRPD-CVV
VDLAC-------------PAF----DGLAL-ARTIAAFRRRSRQC-------TRIM--GMV-E--HGGLSGE-QVARAFHAGIDDLLDAD----------
TPVDLLVSRIGSLVRRARR-------EEAHIE--------------SARA----------RMALA----------DA------------LRRVNAD----
--LAA------ANRKLIEAQ--------------AKLVQSAKMASELAAGIAHEFNNPLAFVLAHENTVKRSRSQDTKGSERLSASLIGLSRMRDLVASL
RRFSRLEEGEFR----RLDVPEAIGMVLTLLAPKLG------QDIEVTCKLEAP-PELVCQAALVNQVVMNIVSNAADAIPHADRILITSQAENGKYVIQ
ISDTGPGVPKELQERVFEPFFTTKPVGS----GTGLGLATAYGVVQAHGGNVVVTNASLGGACFTLRVPYR--------------
>tr|K7SXA4|K7SXA4_GLUOY Sensory transduction protein kinase OX=1224746 OS=Gluconobacter oxydans H24. GN=B932_2120 PE=4 SV=1
-ARVLLVEPDDTHAQRIWRVLLKEGFAVTCLGSGEAALGMVEDLMPDLVVVCSELPGMTGGQLARRLRLDALIPILMLTEDASPGVEREGLESGADAYIS
KSAHPDLLVLRMRALLREGPEL-LQVD----EA----SRLRRARIVIVNSP------RDEDEDEDIPTLGELLWRDGHTVRSDDLIEGGWLRGAPD-CLV
LELGS-------------GE-----EDLKF-CRLLDARRQAVLEAGGI---PFRTL--GIV-E--ASRFRRQ-SSGEFFEAGIDDLVPSD----------
IAIEALAMRIRTLAQRFRQQEIERQQNALTLE--------------AARA----------KAEMA----------EA------------LAQANME----
--LAR------TNEQLIQAQ--------------SKLVQTAKMASELVAGIAHEINNPLAFTIAHADTVERTGPEEPKGISRLESMKLGLQRIQNLVLSL
RRFSRLDESSFQ----TVDVPGALDTALALLGHKLG------PDIIIEKDLQAP-AHLVCQPAFLNQVVMNIISNAADALPVEGRIVITSRLENGRYDMT
ISDDGPGLPVELRNRVFDPFFTTKPVGT----GTGLGLAIAYSVMEAHDGTIEITDANGIGACFRLSLP----------------
>tr|G6XKT4|G6XKT4_9PROT Sensory transduction protein kinase OX=1088869 OS=Gluconobacter morbifer G707. GN=GMO_21000 PE=4 SV=1
-PRVMLVEPEDGHAQRICEVLLKEGFAVTCTVSGEVALGTIEETMPDLVVVCSELPGMTGGQLARRLRLDALIPILMLTEDASPGLEREGLESGADAYIS
KSAHPDLMVLRMRALLREGPEL-LQVD----EA----SRLRRARIVIVNSP------REDEDEDDTPTLGELLWRDGHTVRSDDLIEGGWLRGAPD-CLV
LELHN-------------EE-----EDLKF-CRLLDARRQAVLEAGGI---PFRTL--GIV-E--ASRFRRQ-SSGEFFEAGIDDLVPSD----------
IALEALALRIRTLAQRFRQQEIERQQNALTLE--------------AARA----------KAEMA----------EA------------LAQANTE----
--LAR------TNEQLLQAQ--------------SKLVQTAKMASELVAGIAHEINNPLAFTIGHADTVGRTWPPEAKGVSRLESMKLGLQRIQNLVLSL
RRFSRLDESSFQ----KVDVPAALDTALALLAHKIG------PGITIERHLEAP-AELVCQPALMNQGVMNIISNAADALTAEGKIVIASRLEDNRYEIT
VSDDGPGLPPELRNRIFDPFFTTKPVGT----GTGLGLAIAYSVMEAHDGMVEVTDANGVGACFRLSLP----------------
>tr|G1Y367|G1Y367_9PROT Signal transduction histidine kinase OX=1003237 OS=Azospirillum amazonense Y2. GN=AZA_89815 PE=4 SV=1
-TRVLLVEDSPTQALQLQMMLERRGWSVTVCGDAESALEQLGREMPDLAIVDYHLPRMNGDEFVRRVRMDMRLSVLMLTDSHAADRERQGYDSGADAYVP
KSVDTDILLSRVGALLRKTTAA--AAQA-PVD-------IRQSRLLVVD---------DSPTYLFF--ITAQLQEDGHEVSGREALAR-MAEEKFD-CVV
VDLVM-------------PEM----SGTEL-CQHLDRMRRQHD----R---LFQII--IL--T--SRDNKE--DMMRGLEAGADDFVGKA----------
GESEILKARIRALLRRNLRISGEFRDKELELE--------------RTRDE---RRIAQERAAMT----------EA------------LERSHAE----
--LAE------AYQELQGTQ--------------AQLVQAAKMASALVAGIAHELNNPLAFVGNHLGTVLRCQGHLRKMRQRLDAMRLGIDRVENLVVKL
RTFSRLDEAEVK----EVEIEDSLESVLTLLQHKLS------DRITVERRYEGP-KRITCQPGPLNQVLMNVVGNAIDAI-GTGTITLATGRNGAMFRLS
VRDTGHGIPAAIRDRICEPFFTTKPVGS----GTGLGLSISYSIIQRHRGRLEFHSDEGRGTEVVIEIPMD--------------
>tr|Q5FU93|Q5FU93_GLUOX Sensory Transduction Protein Kinase OX=290633 OS=Gluconobacter oxydans (strain 621H) (Gluconobacter suboxydans). GN= PE=4 SV=1
-PRVVLVEPDCDHARQIAQVLVKEGFALTCATSGEEALGTIEETMPDLVVACTELPGMSGGQLARRLRLDALIPILMLTEDASPGVEREGLESGADAYIS
KSAHPDLMVLRMRALLREGPEL-LQVD----EA----SRLRRARIVIVNSP------REDEDEEEVVTLGELLWRDGHTVRSDDLIEGGWLRGAPD-CLV
LELGS-------------GD-----EDLKF-CRLLDARRQAVLEAGGI---PFRTL--GIV-E--ASRFRRQ-SSGEFFEAGIDDLVPSD----------
IALEALAMRIRTLAQRFRQQEIERQQNALTLE--------------AARA----------KAEMA----------EA------------LAQANME----
--LAR------TNERLLQAQ--------------SKLVQTAKMASELVAGIAHEINNPLAFTIAHADTVTRTASDESKGMSRLESMKLGLQRIQNLVLSL
RRFSRLDESSFQ----KVDVPAALETALALLAHKLG------PGIIVQKDLQAP-AELVCQPAFLNQVVMNIISNAADALIVRGRIVIASRLENGRYEMS
VSDDGPGLPPDLRTRIFDPFFTTKPVGT----GTGLGLAIAYSVMEAHDGVIEVTDANGIGACFRMSLP----------------
>tr|D5RGU8|D5RGU8_9PROT Sensor histidine kinase OX=525371 OS=Roseomonas cervicalis ATCC 49957. GN=HMPREF0731_0307 PE=4 SV=1
-PTLLLVEDSDTQALQMRRLLEAEGFAVTRAATAELALEALNQALPALVIVDYHLPGMNGDELARQIRLNSRLPVLMLTEAREGDVERQGLESGADAYVP
KSADQALLLLRIRALLRRRAA---GATP-GQGG-----VFRRARMLVVD---------DGATYRTY--LAGLLTREGYAVSAEAALEA-VAASPWD-CVV
MNAFS-------------AGF----DGVLL-CARLNALRAAALDGGGP---GFQIV--ALGPE--STAGRE--MLTGLFEAGADELVPAT----------
AEARVLSLRIRAALRRDRRSAAELREREMSVQ--------------RAQAE---AAAAQAKAALA----------EA------------LARANDE----
--LAD------TNRQLKDTQ--------------TKLVQAAKMASELVAGIAHEINNPLAFILAHQGTVERLDAAAPRCRDRSRSMTLGLKRIQDLVLNL
RKFSRQDD-AFQ----RVNVPDALDTVLALLAHKLG------ERIEVRRDYRAA-PELRCSPALLNQVVMNIVANAADAIAERGHISIATESDGQTYRIA
ISDSGPGVPEGLRERIFEPFFTTKPVGA----GTGLGLAIAYNVIQAHDGTISVGTGPEGGASFVISVPMQ--------------
>tr|C5AVV5|C5AVV5_METEA Putative Sensor protein, CheY-like domain OX=272630 OS=Methylobacterium extorquens (strain ATCC 14718 / DSM 1338 / AM1). GN= PE=4 SV=1
-PRLLLVEDSETQALELQLQLEGQGFSVQRCATAEAALDLLNTDLPDLVVADHHLPGMNGDEFTRQMRLSLRLPVVMLTSARNG--ERHGFESGADAYVE
KSADRDLLVLRIRALLRERKS---SATE-GPSG----AAFRRGRVLIVD---------GSATYRAF--FTGLLTQEGHTVDRSGALAA-LDEPGFD-CVT
LDLVG-------------SAY----DGIAL-CTEIAERRMKAPEGGGN---AFPLV--GMA-G--DKPDKS--LLVAAFAAGADDVVSK-----------
ADGEVLAMRVRGLVRRNRRISGEFGDRERAVE--------------RARAE---AEAAAARAALA----------DA------------LGQANRD----
--LED------ANRKLTEAQ--------------AKLVQAAKMASELVAGIAHEINNPLAFILAHQGTVERLAPEGRKARDRVGSMRLGLTRIQDLVLNL
RKFSRLDEGERG----LVNVPEAIETVLALIQHKLG------TRITVTRDFSGR-AEISCTPALLNQVVMNILGNAADAIHGDGTITVATYSDAETDMIR
ISDTGPGIPEELREKIFEPFFTTKPVGS----GTGLGLAIAYSVVQAHSGSLIVETAPGGGASFVIGIPRQ--------------
>tr|D6Z2N0|D6Z2N0_DESAT Multi-sensor signal transduction histidine kinase OX=589865 OS=Desulfurivibrio alkaliphilus (strain DSM 19089 / UNIQEM U267 / AHT2). GN= PE=4 SV=1
-ARILVVDNNPLIVKMLERFLTDEGFEVKSAADGLAALQVLDEYTPDLIFVDLIMPNISGEKLCRVIRATDSVRLVVLSAVVAE--ENVDFQAGADACIA
KGPFAELKE-NIRAVLAMLVQ----QPE-QAAR----EIIGRENLLQ-----------RGLDIRRY--FDAILQSMSDGVRQRRIVMIGWPEEKSS-NLL
DHLSA-------------AAA----TLLEAAEREIATTGKVAA---------PCVI--GE--E--EEVLLGG----RQVLLTLLPLVERQ----------
DSSCWLVMRAAALQQRIERQTAELAQRYRELQ--------------SEVE-----RRKQTEAALQ----------AS------------HDELEAR----
--VAA------RTAEVEKLY--------------SQLLHSEKLRAKLAASIAHEFNNPICGIRNVLQGLQRRAAGD---HDLVAMAVRECDRVARLTSDL
QSFNRPTSSQLV----MLDVHAALKDILLLCQKDLN------GKVEVRQELAPDLPPVRAVPDQLKQVFLNLLTNAREAIPTGGRIVIATRREDDEVMIS
FCDSGCGIAAENLERIYEPFFSTKPAVK----GTGLGLAVSYGIVQRHGGRLEVESREGQGACFKLFLPLP--------------
>tr|I4YT22|I4YT22_9RHIZ Histidine kinase,Response regulator receiver domain protein,histidine kinase OX=754501 OS=Microvirga sp. WSM3557. GN=MicloDRAFT_00036680 PE=4 SV=1
-AEILLVEDSETQALQLRHMLETNGFNVSWRSTAEAALDSLNEKLPDLVIADYHLPGMNGDELTRQMRLNVRIPVIMLTEARERTVERQGLESGADAYIS
KSAEQELVVLRIKALLRRRSSPIREERQ-SPSF----GTFRRACVLIVD---------DSSTHRTY--LQNLLTHEGYAVEPAEALRL-VRRVDWD-CIL
VNLLS-------------AGF----DGIEL-CRQLNLYRGLAPLPGADA-PSFAIV--GL--G--HEDGGE--LLARAFAAGVDDIVPST----------
VEADVMRVRIRALVRRNWRIEAELRERELALA--------------RARAE---AAS-------A----------EA------------LANANRE----
--LEE------ANDLLKGTQ--------------AQLVQAAKMASELVAGIAHEINNPLAFIQAHQGTVDKLPPEARKSRDRVGAMKLGLARIQELVLNL
RRFSRLDEGDFQ----TVNVPESIETVLALLGHKLG------TRIDVRRHYHAV-PDLYCSPALLNQVVMNIVGNAADAIKGTGGIDIETESNETTYTIK
ISDTGPGIPGELRERIFEPFFTTKPVGS----GTGLGLAIAYSVVQAHKGSIAVDAGPHGGAQFTITIPRR--------------
>tr|I9X349|I9X349_9RHIZ Response regulator receiver sensor signal transduction histidine kinase OX=1096546 OS=Methylobacterium sp. GXF4. GN=WYO_0030 PE=4 SV=1
-PRILLVEDSETQALELRLLLEAHGFAVERCPSAEAALDHLNRTQPDLVVADYHLPGMDGDELIRQMRLSLRLPVLMLTGGGGG--ERKGLESGADAYLP
KSADRDLMILRIRALLRERRA---SGDE-GPGA----AAFRRGRILVID---------GSLTYRTF--LAGLLGQEGHHVGPEAALNA-LDGVAFD-CVT
VDLLG-------------HAY----DGLTL-CRAISQRRSGQAAGAG-----FHLV--GIA-G--SDPAKD--FLVEAFAAGADDVVSK-----------
TDAEVLALRVRGFVRRDRRIAGQFGERERAVE--------------RARAE---AEASEARARLA----------DA------------LERANRD----
--LAD------ANRQITEAQ--------------AKLVQAAKMASELVAGIAHEINNPLAFILAHQGTVERLPEAARKARQRVGSMRMGLTRIQDLVLNL
RKFSRLDEGERA----LVNVPEAIETVLALIQHKLG------DRIAVERSFAGR-PEIHCTPALLNQVVMNILGNAADAMPEGGMIRINTLSTPEVDEIR
ISDTGPGIPEDLREKIFEPFFTTKPVGS----GTGLGLAIAYSVVQAHSGSLTVEAAPDGGACFVIGIPRQ--------------
>tr|B8IMV6|B8IMV6_METNO Response regulator receiver sensor signal transduction histidine kinase OX=460265 OS=Methylobacterium nodulans (strain ORS2060 / LMG 21967). GN= PE=4 SV=1
-PRILLVEDSETQALQLRLLLEASGFAVTRCATAEAALDALNAGLPDLVVADYHLPGMNGDELTRKMRLSLRTPVLMLTEAQGRDVERQGLESGADAYVP
KSADHDLLVLRIRALLRERGT---VGPQ-DSAHG---GAFRRARLLVVD---------ASATYRAY--LAGLFGQEGHAVGPDQALAA-LAAPEFD-CVT
VDLLS-------------SAY----DAIAL-CRRIAA--LRGDPGGSP---DFYLV--GIGSA--AASGKD--LLVQAFSAGVDDVVPKG----------
AEGEVLAIRVRTLVRRNRRVADEMRQHELAVE--------------RAQAE---AAAAEAKAALA----------GA------------LEQANRD----
--LAD------ANRQLKDAQ--------------AKLVQAAKMASELVAGIAHEINNPLAFILAHQGTVERLSGEAAKARDRIGSMRLGLTRIQDLVVNL
RKFSRLDEGELR----SVNVPEAIETVLALIQHKLG------TRITVERRFKGE-PEICCTPALLNQVVMNVIGNAADAIPGEGRITIETRSEAGNDVIR
ISDTGPGVPEALRERIFEPFFTTKPVGS----GTGLGLAIAYSVVQAHSGTISVETAPGGGACFVISIPRR--------------
>tr|Q2W5V4|Q2W5V4_MAGSA Signal transduction histidine kinase OX=342108 OS=Magnetospirillum magneticum (strain AMB-1 / ATCC 700264). GN= PE=4 SV=1
-NLILIVEDSVTQALKLQLVMEQEGFQTVCAHSGEEALEQINRCRPSLIIVDYHLPGIQGDELCRQIHMDITIPLMMLTADETSAAELHGLESGADDFVA
KSEDPEILLLRVHNLLRKARRE--AVNV-EVGR----SLFRRARVLIID---------DSMTYRES--LAQELTDEGCDVSGVDGLRL-LAESDFD-CVM
VDMVM-------------PGM----DGIAV-CKELSKLRSDND----A---PLVVL--ML--S--AYEHKE--NVARALEAGADDFVGKS----------
TEMSLLRARLRALLRRNQRIVEEIRLREMETL--------------RAKAE---KEAAEARAALA----------EG------------LARANRE----
--LEE------ANAKLRETQ--------------VHLIQSEKMASQLVAGIAHEINNPLSFALSNVFSIENWAPCLVKARKRIADTGQGLERVRELVVKL
RTFSRLDEGEFK----TVDIKEAVESVLLFLRHKMS------DRIEVRRNFAED-NMLACYAGQLNQVIMNVVANAVDAI-GKGVITVRTFRQDGMFAIA
VSDTGSGIPPEIQERIFDPFFTTKPVGQ----GTGLGLSISYGIIKSHDGRIEVSSHPGQGTEIRILIPIN--------------
>tr|A4TUV3|A4TUV3_9PROT Response Regulator Receiver Signal Transduction Histidine Kinase OX=55518 OS=Magnetospirillum gryphiswaldense. GN=MGR_0144 PE=4 SV=1
-SLILVVEDSATQAMRLQHVLETEGFTTVCCYSGEEALDQMNRVLPDLIIVDYHLPGIQGDELCRQIHMNLTIPILILTADETQATELHGLESGADDFVS
KSEETDILLLRVHNLLRKSRHD--TTVL-DVAR----SLFRRARVLIVD---------DSPTYRQS--LTEELRDEGCEVGAREGLQA-LADDDFD-CVM
VDMVM-------------PEM----DGVAF-CKALGERNRDGD----A---PLVVL--ML--S--AYENKE--NVARALEAGADDFIGKS----------
TEMSVLRARLRALLRRNQRIVEEFRLREMEAL--------------RAKAE---KDAAEARAALA----------EG------------LARANRD----
--LEE------ANQKLRETQ--------------VHLIQSEKMASQLVAGIAHEINNPLSFALSNVFSVEGWADALAKSRSRMTDTAQGLERVRELVVKL
RTFSRLDEGEFN----TIDVREAMESVLLFLRHKMT------GRIEVVRDYASV-NDLACYGGQLNQVLMNIVANAVDAI-DQGIITVRTGVEGDMFAIS
VQDSGSGIPKENMERIFDPFFTTKPVGQ----GTGLGLAISYKIVQAHRGRIEVASELGQGTEFRVLIPRT--------------
>tr|H0A912|H0A912_9PROT ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein OX=1054213 OS=Acetobacteraceae bacterium AT-5844. GN=HMPREF9946_05323 PE=4 SV=1
-MAILLVEDSETQALQMRRMLEDEGFGVQRAATAEAALEALNGPLPDLVIADYHLPAMNGDEMVRQIRLNSRLPVLMLTEARERDLERHGLESGSDAYVP
KSAAPELLLGRLRALLRSRVE---APAE-NTGG-----TFRRTRILVVE---------PSATQRLA--LVTQLQREGHAVTAEAALDI-LQDEPFD-CVL
LNA----------------GF----EGVDL-ASRLHALR----DETGA---LFQIV--ALLED--GAAGSEEVLMGQLFAAGADDLIATP----------
APAEVLSVRLRAALRRERRTAEAARERALTIA--------------R----------AEARAAMA----------EV------------LARTNAE----
--LEA------TNQELRDTQ--------------TQLVQAAKMASELVAGIAHEINNPLAFIQAHQGTVERLASEAPRARERAQSMTLGLARIQELVANL
RRFSRQDDGAFQ----RVNVPEAMETVLTLLGPKLG------DRLTVERDLQGV-EELVCLPALFNQVVMNLVSNAADAIPGQGRISIGTRSDWRSYTIT
VTDTGPGVPEKLRDRIFEPFFTTKAIGQ----GTGLGLAIAYNIVSAHEGTITVGASAEGGARFTVSVPIR--------------
>tr|D8G210|D8G210_9CYAN Putative Sensor protein OX=272129 OS=Oscillatoria sp. PCC 6506. GN=OSCI_3110006 PE=4 SV=1
-LNILLLEDSILDAELIEEYLIEGGIKCYLVETRLDFIEAIEKDSFDLILADYSLPSFDGISALAIAQACSDVPFIFVSATLGEELAVETLKNGATDYVV
K--ELGRLVPAVKRALREQERRDRLLAEAARQSERFEIMADT---APVIWMSDTDKLCDYFNKPWLEFTG-R--TLAEEIGN----------GWAQGVHP
DDVELDTYTTAFDAR--------LDFKIEYRLKRFDYRWLLDTAIPFNADGT----F------VGYIGSCTTEAALQKASQEIVNILESDGFASILGKQR
SEYPPFALRWHPTP-----TEAALRATEEKLKSFVAAASIGIVFADIYGSITDANAEFLRIVGYSREHLR-RGELRWTEITPPEYDEQSIKEGKKTGVKE
IRSDGSRVPVLIGFILVGEQRE--ESVA-FILDLTERKQLNRLKDEFLATLSHELRTPLNAMLGWTQLLRSRKFDEEKTARALETIDRNTKSLAALIEDL
LDVSRIITGKLRLNLRLVDLVSVVEAAIETVIPAAQ-----AKSIQIIPLLDERIERISGDSSRLQQVIWNLLSNAIKFTPNGGCVTIAIHRVGSEAEIE
VTDTGQGINPEFLPHVFDRFSQADSTTTRSYSGLGLGLAIVRHLVELHGGTVKADSQSGKGSAFTVRLPL---------------
>tr|K9X4Z8|K9X4Z8_9NOST PAS domain S-box OX=56107 OS=Cylindrospermum stagnale PCC 7417. GN=Cylst_4665 PE=4 SV=1
-LNVLIVEDSEADAMLVLRELHRGGFNPIWVQTAQELSVALNRCSWDVILSDYRLPGFNAPAALEIVKQQKDIPFILISGIIGEVSAVEMMKAGAHDYVM
KD-NLNRLPEAVRREIRDQVRAERQQAQAELEQRFLRQVFDV---VPNIFVKDTQGRFVTINQAGAMAYG-V--KVEEIIGKR--------ENDLTNV--
----EQTKHHLVNNQ--------EVKQIGQRQIYPQVRWYKTIVEPFVDTQGGV-QV------IGSATDITAQAALQHSQKLLQTLASNGMIYTLLELTP
EEWPSVRPECRENGEQLLARERHYVKQLQELTTAALTINFALSVEQLTDQAASIIGTHQSITNWAQAITA-IYLSDKYAAWRNYDDGSGIYAGKEAENPL
GRNGQNIGLIQLSDKYEGEFTE--TDEA-ILVQLAQMASVNRIKDEFLAVLSHELRSPLNPILGWSRLLQNGSLDEAKTKIALTTIERNAKLQAELIEDL
LDVSRILRGKLSLTSSPINLASTIKAAIETVRLATE-----AKSIQIETMLDPVVGLVSGDSTRLQQVMWNLLSNTVKFTPAGGRVEVRLEQVDNQAQIT
ISDTGMGISPEFLPHVFDYFRQADSTTTRKVSGLGLGLAIVRHLVELHGGTIEAESQEGMGATFTVKLPL---------------
>tr|F5UB98|F5UB98_9CYAN Multi-sensor hybrid histidine kinase OX=756067 OS=Microcoleus vaginatus FGP-2. GN=MicvaDRAFT_4289 PE=4 SV=1
-LSILLIDDNPNDRLMIERELRKTFPDLEIAIDIQTLEHILAAGGFDIVITDYQLHWSDGLTILQKVHSYPNCPVIMCTDSGSEQVAVEAMKAGLSDYVF
KG-RLKRLAGAVGESLKKQLRENYAKTSAQLASERLRLAIEA---SKMIWDWNVLTGEVVWSEEQELLFG-L--EKGSFPGTY--------EAFFACIHP
DDQAARALAFALENK--------IEYKYEFRVLWPDLHWIAARGKFFDDDTGKS-VS------SGLVWDITSEARVQESEENLRFALEATIAFTQMGLGP
DEYPDLRVVFDASGSRALARERSYLRRLQKLTSASVAINSTLSVAEIADSARQILEVHQVAVNWDEGISK-FSMSEKYAAWQDYCDGTGIYQGKAAGKPL
TRDGRNLGLIQLSDKYEGEFAE--DDET-ILMQLAQAVSGNRMKDEFLATLSHELRSPLNAILGWAQLLQQRSLSPAATGRALETIERNAKLQTQLIDDL
LDISRIIRGKLTLNPCAVNLISMVEGAVNTVRLAAD-----AKSIKLQFAITPESDLVSGDPGRLQQVIWNLLTNAIKFTPRGGRVEIRLSRVDSEVELA
VTDTGIGVAPNFLPYVFDSFRQADATITRNYSGLGLGLAIVRQLVELHGGRVWAQSPLNMGSTFTFRLPA---------------
>tr|F5UEQ9|F5UEQ9_9CYAN Multi-sensor hybrid histidine kinase OX=756067 OS=Microcoleus vaginatus FGP-2. GN=MicvaDRAFT_1135 PE=4 SV=1
-LSILLVEDSPLDAELIEAYLMDGGLKFSLVETREDFATALEKQSFDIILADYMLPCFNGIAALEIAHTCPGVPFIFVSATLGEEVAIETLKSGATDYVL
K--RLIRLVPSIERALREQERNERKQAEAQQQSERFRIMADT---APVIWMSDTDQLGDYFNKVWLEFTG-R--TLAQEMGT----------GWMENLHP
DDLSLDIYQKAFKAG--------SEYRVECRLRRYDYRWVLGTGVPYRPDRT----F------AGYIGSYLTAKALQLANDQITNILESDAFIALLGRPK
AEYIPLKMRFYPSD-----TEAALQASEEKLRMLAEANLIGIIFGDVNGSIIEANDEFLRIVGYTREHLQ-RGELNWIDITPPEYDKKGIAEAQATGAKE
WRKDGSRIPVLIGYVLLPHKRQ--ESVA-FILDLTVGKQLNRIKDEFLGTLSHELRTPLNSMLGWAQLLRNRKFDEKTTVRALETIDRNTRSLATLIEDL
LDVSQIITGKLSLNLRWVDVVSTVEAAIDTLAPAIA-----AKNIEMVTDFDPNAGRIFADSGRLQQVAWNLLSNAIKFTPNGGQVKVEVRKMQGTVEIE
VSDTGQGISEEFLPHVFERFSQADSSTRRSYNGLGLGLALVRHFVEMHGGTVQAESAKGKGSRFLVRLPI---------------
>tr|K9TG36|K9TG36_9CYAN PAS domain S-box OX=56110 OS=Oscillatoria acuminata PCC 6304. GN=Oscil6304_1399 PE=4 SV=1
-LHILLLEDSLLDAELIEAHLLESGLNVALVDTCDAFQNALESGSFDVILADYSLPSFDGFSALKMAQLCPDLPFIFVSATLGEEVALETLKNGATDYVL
K--QLERLVPSVQRAIRETEHRDRLKAEAALQSDRFRMALKN---SFIIFQQDRD----------LKYQ------------------------WIHNPQP
ETAEV--------GE--------TDYFL---FSEADYREVIATGSPFEISVT----I------SGEIRDYTSERELYRREQQFRALAENDIIARATGIPP
Q-FVTLEFEF-PSS-----AEQVLRESEARFRRLMDSNTIGMGFWH-GEAITVANDAFLEMMGYSQEDLQ-REPLNWREITPSEYDANANQQARQTGYKE
FHKDGTRIPVLLGGAIFDNNAD--AGVF-FTLDLTERKRMNQVKDQFLAVLSHELRSPLNAILGWSQLLLARKFDEATTRRALETIERNARFQTQLIEDL
LDVSRILRGKLTLKVTRVNLSTPICAAIESLRLAIE-----AKSLQLDYSPNPSVSPVMGDSNRLQQVVWNLLSNAVKFTEPGGQVSLNLKQQDHWVILQ
VQDTGVGILPEFLPHLFEYFRQADASSTRNHGGLGIGLGLVRHLVELHGGTVSAESPEGQGATFIVKLPA---------------
>tr|E0UL00|E0UL00_CYAP2 Multi-sensor hybrid histidine kinase OX=497965 OS=Cyanothece sp. (strain PCC 7822). GN= PE=4 SV=1
-LRVLIIDDNRDDRALAIHQLKKSFSEIEIVGTEAQFSQVLSNYLFDVVITDYQLHWSNGINVLKIIKAHPTCPVIMFTNTATQETALEAMKCGLNDYVV
KSPSYVRLPAAVQAALER------VAAQVKAALQRIQTLLNH---LNVIYRLTAKGLLLEANPAFLRLLG-L--QSITEIPST--------HSLQAYFEP
DHYTLAQLT---QNG--------EAQEREIQLRCADTRWVK-ISTTFTQESSDI-II------EGLMEDITAQARAETEKQRFQFLANA-----------
--------------SRLFASSLDYHLTLKNLVNLVVPTLADICVIDLDEPIVAATDPSLSALNYP-LSAD-YGAVKLLNINQSELVSSSVWQGIQASMPM
VHDRNFGTITLISTKTSRTYDH--TDLA-LAQELARRAAINQIKDEFLAIVSHELRNPLNAMLGWSQLLHKREFEDTMVNQAITIIERNALLQKKLIEDL
LDISRIIQNRLHISREPVYLIPLIDTVIDTLRPNIK-----AKAIEISSNLDTSTKPVFGDAYRLEQIVGNLLSNAIKFTSTGGKINVQLSQEGSLAKIT
VADTGQGISPEFLPFIFERFRQADPSKTRSQSGLGLGLAIVRHLVELHGGSVYAASPVGKGATFIVQLP----------------
>tr|K9XDS0|K9XDS0_9CHRO Multi-sensor hybrid histidine kinase OX=1173026 OS=Gloeocapsa sp. PCC 7428. GN=Glo7428_2085 PE=4 SV=1
-LRILLIDNNPDDRALAIRELGRAFPEAQIVGIAEQFEQVFINFLFDVVITDYQLHWSDGLTILRTIKAYPNCPVIMFTSTATQEIALEAMKSGLDDYVI
KSPSYVRLPAAVETALER------IAAQQQAALQRVQTLLNQ---LDVVYRLTSDGTLLEGNAAFLRLLG-L--GSLTEVPPN--------QTLESYFQA
QDYALAQLK---QNS--------EVRDREIQLRCADTRWVK-ISKTFTRTNGTT-II------DGLMEDITAEAQAELEKQRSEFLAEA-----------
--------------SRLLSSSLDYRTTLENLVNLAVPTLADICLVDVGEPIVAASEPEQAALRYPPADAD-YGSIKVLRTGQSELISDSIFEGVKASIPM
VHDRKFGTIALVKTKAIRRYDR--ADLE-MAEELARRTAINRTKDEFLAIVSHELRNPLNSMLGWAQLLRKRQFEDPTVSRAHEIIARNARLQNKLIEDL
LDVSRIIQNRLEISRQSVYLVPVIDAAIETFRPNAE-----AKAIQISSHLDPLTGQVLGDSERLEQVVSNLLSNAIKFTPNGGRVEVRLEQVGSLAQIT
LTDSGQGISADFLPFIFERFRQADASKTRSQSGLGLGLAIVRHLVELHGGTVYAASEEGKGTTFTVQLPL---------------
>tr|K9QHR5|K9QHR5_9NOSO Multi-sensor hybrid histidine kinase OX=317936 OS=Nostoc sp. PCC 7107. GN=Nos7107_4372 PE=4 SV=1
-LRILLIDDNPHDRLLAINALEREFVDLKIIARPQEFEQALSVGEFDLVITDYELRWSNGIEVLRNIKSYPEIPIVMFTNNGSQEIAVEAMKSGLDDYVI
KSPSYMRLPVAVRLALKQ------AVTRHQMTLERFQTLLNQ---LNVVYRITADGIVLDANAAFLQLLG-L--DSLTEISFN--------QTWRSYFST
EDDAWQQLR---IDA--------GVRERELLLHRPDEIWVR-ISQTFTTNGDTT-II------DGIIEDITAEKALQESEARFRWIFES-----------
--------------N-----------------------VIGICFWNSDGNITAANDAYLQLVGYTRADMK-TGGLHWTDISESEY-------GISTPVKC
IHKAGYRVPILIGCAFREGSQT--DGFT-FVVDLTERKQANRVKDEFLAILSHELRSPLNPILGWSKLLVTHKLSESKISEALATIERNAKLQAQLIEDL
LDISQILRGKLSLNIASVNLQSVISAALETVQLAAQ-----AKAIEIQTTLSANVGTVLGDPVRLQQVVWNLLSNAVKFTSSGGRVEVRLEQVGRQAQIQ
VIDTGQGISSEFLPFVFDYFRQADSQTTRRFGGLGLGLAIVKHLVELHGGAVWAASPEGQGAIFNVRIPL---------------
>tr|A0YR25|A0YR25_LYNSP Periplasmic Sensor Hybrid Histidine Kinase OX=313612 OS=Lyngbya sp. (strain PCC 8106) (Lyngbya aestuarii (strain CCY9616)). GN=L8106_11662 PE=4 SV=1
--TIICVDDERVVLISLRLPYLGEKYNVELAESGEEALEIIEELQLDLIISDLIMPNMTGDELLKQRRKTLKILLTGQASTDAIGNAVNSASL--YRYIA
KPWSETDLCLTVTAALRSYQ-RDKQLSEQNAA----------LHKINQELLLKREEEQLRKSEERWQLALRGSNDGI------WNVQTMLGYEDIGNTEW
SE------RVHPEDLPPTLAAIHIKRKTTYFTFRMRCFDENGEAVRFEEDNLLSRISEQFLNQTIHLTLE-ATGEFITQLPDEAEAEKAELKRSLLMQLT
GNLVQRVGALIAIAQAKNEAERALRDSEARFAGILDNADEAIISIDETQHITLFNQGAEKIFGYSQAEVLGQALDILLPLRFAHDFTQAPLSARKMSERN
RRRDGEEFPIEASISKLELGNK-RIYT-AFVRDITKRKRAERAKSEFLANMSHELRTPLNGILGYAQILQRDKNITPQQRKGLGVIKQCGSHLLTLINDI
LDLSKIEAQKLELHPTDFDFLTFLCGVSEICRVRAE-----QKNISFTYQTSQHLPSLHADEKRVRQVLINLISNAIKFT-DTGCVIFTTELGHTPIRFL
VQDTGIGIPSEQIEKIFIPFEQVG-DRFRKAEGTGLGLAITQKIVSMMGSTLNVESVVGKGSKFWVDLDL---------------
>tr|F5UMI0|F5UMI0_9CYAN Multi-sensor hybrid histidine kinase OX=756067 OS=Microcoleus vaginatus FGP-2. GN=MicvaDRAFT_5012 PE=4 SV=1
--VIICVDDEPIILESLKKKTLGEEHLLETAEGGEDALELIEELLAEAVISDYLMPNIKGDELLKQIPKTIKIMLTGQADLEAVANTIKYAKL--YRYIS
KPWQSEDLKLTVKEAINSYF-REKQLAEQNAQ----------LQKLNQELLVEERTAQLRLSEEKFAKAFRSSPNPI-TITRLDYLEITIGYSAILDRTA
LD------LNLWENIQAHAELFLDEKQI-ILNFNFRTIDIHGET-CVEEAAAQRIARVGNWECFTTTWSE-ELSRIRILRLEPEIAADNCPSQGFIVNQQ
GQVTKLFTTLMDITP-RKLAEIALAESEEKYRHLVETSQDIIWSCNAQGHITFVNQAVKQIYGYEPEEMLGCSFSDLAPGEIKWELQQRLLTGKTVFQYE
LGKDGRKIDVNTAIARMDAEGN-IIGTTGTASDITERKQAERAKSEFLSNMSHELRTPLNAILGFSQLLARDPNLGADQQQYLGIISQSGEHLLVLINNI
LQMSKIEVGLVTLNNSTFDLHKMLKNTENMLKLQAG-----KKGLQLIFDCRPDLPYIEADESKLRQVLINVVGNAIKFT-AEGGVNLRIKHELPELLFE
VQDTGSGISAEEMDNLFKPFAQTE-SGKKAQEGSGLGLPISKQFVQLMGGKMTVTSTLGRGSIFRFDVKV---------------
>tr|K9SQM8|K9SQM8_9SYNE PAS domain S-box OX=1173263 OS=Synechococcus sp. PCC 7502. GN=Syn7502_00288 PE=4 SV=1
--DILVVDDT---LSNLLRILTKHGYTTRCIPSGELALAEVQMYCPDLILLDIHMPGLNGYEVCQHMPTIQDVPIIFLSALDSVADKIKAFDLGAADYIT
KPFQAQEVLARIKHQLKIRD-LQKQLEEQNTR----------LQREIQD--RNDASTALILSEAKFATAFRSTPHAI-AITRRDHLDVFSGYTRIIGRTS
LE------LNMWQNFDDRQKFILTQKGY-VRNIELRLITINGEN-CIEERSLLENIADALFVHLITDVNQ-RACQNKAMKPGTPITINGINRHTFPFELS
GELS-VIGLIRDVSA-RVAAEEALRSTEEKYRSIFENAVEGIYQTTHDGQYLSANPALAQLYGYESAGEMMFAIDDVDPHR-RQDFIDLMEACGTISGFE
YRKDGSIIWISEARTVRDSQGR-LLYYEGLVENITARKLAERAKSEFLSNMSHELRTPLNAILGFTQVLVRDASLSPDHQESLQIINRSGEHLLCLINDV
LEMSKIEAGRATLNCGSFDLHYLLMNIEEMLKYKAK-----SKQLRLTCEIAPNVPYISGDEGKLRQVLINLMGNAIKFT-NRGTVTLRVQTTGQQLLFE
VQDTGTGIAAHEIDSLFEAFIQST-SGRKSQEGTGLGLPISRQFVRLMGGDITVSSTVGVGTIFSFEIPV---------------
>tr|D4ZVQ7|D4ZVQ7_SPIPL Two-component hybrid histidine kinase OX=696747 OS=Arthrospira platensis NIES-39. GN=NIES39_K02250 PE=4 SV=1
----------------------------------------------------------------------------------------------------
------------MWGPVSTL-LYRDMNQNN-------------HKLPHR--LQQLETALAESENRLRDLFHLAPIGI-AEISTEFLAVWVGYSQLINLNF
NA------ITHPEDGDICREKFLINREIDKYTKRYRHLDVMGNPLCAEQRLLLDNIPQQVFWKTFRGCNR-NWAEANVVAPKQKLGPGGRRIWRIPLDSQ
GNVLGILGVLEDITE-RKEIDEKLRLTQ----FSIDKSRDYVLFSDINGRFFYVNEAACKILGYSQEELLTMEVEDIDPLASGWSIAWDDLRDQGSFTFE
YTKTGQAIAVEITLSYLEYNHR-EYGC-AVVRDIRDRKQTERAKSEFLARMSHELRTPLNAILGFTQLMERELYHSPDHKEHLEIIGRSGEHLLELINDV
LEMSKIEAGRVSLNPTNFNLISLLNSLREMLELPAS-----SKKLTLDFAIDDNIPYIYADEQKLRQCLTNLLGNAIKFT-LQGGVILRVKLGKGQLCFE
VQDTGPGIDASEMDLLFEPFSQTE-TGRNSQQGTGLGLSITQKFIGLMGGEIQVSSERGKGTIFRFDIQV---------------
>tr|F1VLT5|F1VLT5_PROAA Response regulator receiver domain protein OX=765070 OS=Propionibacterium acnes HL013PA2. GN=HMPREF9568_01919 PE=4 SV=1
--PILVVDDDAALAEMLQLVLIKEGFSTAGVGHGSDVMDVFREHRPALVLLDLMLPGRDGIRICQDIRRESGVPIIMLTARTDTPNVVQGLGAGADDYVC
KPFRSAELIARIRARLRTPVSR----REE-----GEVITVGDLTIDPVAHLVQLGGEEISLTPLEYSLLVTMAQYPNRVFSRETLLREVWGYTNITDTRL
VNVHVQRLRSKVERNADHPPLLAGRAGRGWWCPSWLTGPRRLWWSSLPLRTVTVTLSSSLVILGGFFLVRQATAGIVEAKRTTINRIQGQLRDTD-----
LRTASFYERLNLLA-------DDAASQSDQYHVLIQGPVSGLISTDHVGIVYFIFPAAVELLRRSVISIAVTTYLATR------HISLPIRQASITASKL
AKALDERMVVRGDLATLASSMND-M-AAQLDLRIGELEKLSSLQQQFVSDVSHELRTPMTTMRMASEMVEA-NPDDPVQVRSVELMRAQMERLELLLADL
LEISRFDAGAAQLSLEDCDIVDLVRSEISDVTPLAD-----RLGVSIVLVA-EAAQTAEVDPRRISRIVRNLVSNAVEHA-ERKTVEVTVVGNDCAVGVA
VRDHGVGFEAWQAEKVFGRFWRGDPSRVRTVGGSGLGLAISRQDANLHHGWLTAWGRPNQGAYFRLVVPRQ--------------
>tr|H0QGQ4|H0QGQ4_ARTGO Putative two-component histidine kinase OX=1077972 OS=Arthrobacter globiformis NBRC 12137. GN=ARGLB_008_00260 PE=4 SV=1
----AVVALTDDARDAVASVLNDAGFSVRKASDAGSLAEELEGNRAAVVLLDAEL--TDGYR--------WETPVLLLVDLAGDFDLARLEPWGIADYIS
RDAAPRELTHRVETLIGRARERRR-------IRAEAEFLRESLRNVS---------AAIRGTNSPQQMAGHLVRGFGESLGVDH----VWFTTFQDS-RV
-----PRIS----AQWSLPGHAKLPDTLGAF-------------------------------------EDEAREQTTSLWSAAEALAVPDHQTDQ-----
--SAALAEDLREWSGLGS-----------VRASVALPVGEG---ESALGII-WIA-----QLEKPRDWSRA----E-------IALIQHV----------
---AG-----NLAHSLIQGHL--ISAQLQVLQ---QLRELDKAKTDFLATVNHELRTPLTSITAYLDMIRDGAGGPVGILSMMDVISRNSDRLRRLIEDM
LTVSQQDA-SGNLNLKQVELGQVLRIVVAALRPLAD-----SRNVTITGADSHEDVKVQADEAQLEQVFTNIVANAIKFTPKGGRISISFMEAGGPAVVD
VMDTGVGIPEQEIAQVFTRFYRASNASSAAIPGSGLGLAIAHDIVRRHGGSLELSSVLGEGTTVSVHLPVD--------------
>tr|A0JR47|A0JR47_ARTS2 Multi-sensor signal transduction histidine kinase OX=290399 OS=Arthrobacter sp. (strain FB24). GN= PE=4 SV=1
----AIVADPDSGRSATAGVLVAAGFEVSTASSHEILTGLLEQHKPSIIVADHS---FGGPP--------VDAPLLLLVDLADESAAESLRTLGMADYIA
KPAAPDELVHRADVLISRAAQRSD-------ARQSAERLREKLRLVS---------SNIRATHDPRLISDCLVTGFGETFGADR----VLFTTFDDD-RV
-----PRIS----AEWHRPGLPPVPDGLGLQ-------------------------------------ESSAHRVADRLWSEAEVLAVEDHHVHE-----
--WSPEDQELAAWSEDMG-----------PWASAFVPVGEG---KSSLGVI-WIA-----QLDEPRVWTRT----E-------ISLIQHV----------
---AG-----NVAYGLIQSHL--MSAQQQVVK---QLRQLDQAKTDFLATVNHELRTPLTSISAYLDMIQDGVGGPVEVSRMLDIIVRNSERLRRLIEDM
LTVSRQDG-A-NLHLGPVQLGHTLQIVTVALRPLAE-----LGDVSISLELCDGDPAIIADEVQLEQVFTNLVSNAIKFTPRGGRIVVSCRTDGEPVNVH
VRDTGVGIPEEEIPHLFTRFFRASNATSTAVPGSGLGLAIAHDIVKSHRGYLAVSSELGAGTTITVQLPVS--------------
>tr|B8H976|B8H976_ARTCA Multi-sensor signal transduction histidine kinase OX=452863 OS=JCM 12360). GN= PE=4 SV=1
----VVVADPDAGRAQNTSALRGAGYNVHAAGDAANLAGLLAEGEPAAIIADAAL--LPGLE--------TEVPVLVMVDLDDPWQ-TSLRPSGMHDCIT
KPTSPRELVHRTTALIDQVARRRA-------SRQDAEALREQLRLVS---------AAVRATNDPQEIARYVVEGFGRTFKADH----VRLETFEDN-RV
-----PRIT----AAWDSDGLEPLSDDDLPD-------------------------------------EDSARRTADQLWAGAETLSTDAGDADDAEPSE
HADGGQAADGDAPASGIA-----------NAASTLVPMGEG---SSSLGII-WIA-----SLDKPRKWSRA----E-------LGLIQHV----------
---AG-----NAAHGLIQSHL--ISSQQQVVK---QLQQLDKAKTDFLATVNHELRTPLTSIMAYLDMIQESTEQPGEIHQMLDIVVRNTERLRTLIEDM
LSVSRNDD-T-LMHLTPVRLGHTLDLVASALRPLAK-----LQNVTIALDPVPDDPEILADEIQLQQVFTNLVSNAIKFTPSGGRIEVGSEADGSRATVR
VADNGIGISSDEIDHVFTRFYRASNAMSGAIPGTGLGLAITKDIVARHGGTIDVASTLGAGTTVTVSLPLD--------------
>tr|F0M754|F0M754_ARTPP Signal transduction histidine kinase OX=930171 OS=23796 / Sphe3). GN= PE=4 SV=1
----AIVADPDATRAVNAQALRDAGYTVHCARDSDALAGLLAAVEPSVVVADTS---LSSLE--------ASAPVLVVVDLDDPAELAAMNPSGIHDCIA
KPPPPRELVHRATALISMVARRKA-------ARQKTEALREQLRQVS---------AAVRGTIDPQEIAQHVVAGFGRTFKADH----VWLTTFEDE-RV
-----PRIT----AGWNRPGLEPLTEEALPD-------------------------------------ERQARQAADRLWAGAETLSPAGAE--------
-----EPTAGEVASAGIA-----------NAVSSLVPMGEG---NSSLGII-WIA-----MLDQPRKWSGT----E-------LGLIQHV----------
---AG-----NAAHALIQSHL--ISSQQQVVK---QLQQLDKAKTDFLATVNHELRTPLTSIMAYLDMIQERTEQPVEVHQMLDIVVRNTERLRILIEDM
LSVSRNDD-S-LMHLTPVRLGQTLDLVAAALRPLAT-----LQNVTIAVEPVPEDPEILADEVQLQQVFTNLVSNAIKFTPSGGRIEVGSEADGTRATVS
VADTGIGISSDEIHHVFTRFYRASNAMAGAIPGTGLGLAITKDIVSRHGGRIDVSSTLGSGTTVTVSLPLD--------------
>tr|J7LXJ9|J7LXJ9_9MICC Sensor histidine kinase ResE OX=1118963 OS=Arthrobacter sp. Rue61a. GN= PE=4 SV=1
----AVVADSDHDRAATTSALDAAGFQVFAVKDTASMAIHLQQHRPSVVVAENSL--AHGLG--------SPVPVLLILDAQEFVDLEEVESWRVADYVI
SPVRAGELVHRVETLIGRSRERAR-------SRGEIEALRESLRNVS---------AAIRQTNDPQLIAEHVVRGFGEALAVDH----VWFATFRDE-RV
-----PSIR----AQWNRPGLPLLPARLGES-------------------------------------ENIITETANRLWAEADVLAVVDHRENP-----
--DSKIAKALLDWSGELK-----------PVSTVLLPVGEG---ASALGII-LLS-----TVQKRHDWTRP----E-------IALMQHV----------
---AG-----NVAHGLIQGHL--ISAQQRVLH---QLRQLDKAKTDFLATVNHELRTPLTSITAYLDMIQDGSGGPVGIRKMLDVIARNSDRLRRLIEDM
LTVSMQDG-S-NLDLKPVDIDKLLQVVVATLRPLAE-----SRHVSVSFTEATEDIEVTADEAKLEQVFTNIVANAIKFTPEGGSVGITSAENGRLALVR
IADNGLGIPEHDLPHILTRFYRASNATSAAVPGSGLGLAIANDIIGRHMGRMVFDSTLGSGTTVSVELPVG--------------
>tr|A5GE40|A5GE40_GEOUR Multi-sensor hybrid histidine kinase OX=351605 OS=Geobacter uraniireducens (strain Rf4) (Geobacter uraniumreducens). GN= PE=4 SV=1
-NKILIVDDQKFALQMLRDTLAPLHYVIEEATNGASAVSKAQEFMPDIILMDLVMPEMDGVEACRRIKQTATIPVIVITASKEKDNLLAAFAAGIDDYIT
KPFSDKELLARIRANLFKREAIAM-MELKNKDAETV-LDI---------------SQTITSTLDTREILKKIADHIE--VKRCSIVK--FSEEGYGFVLS
DNPSAKGIRIELSRYPELLEVIRSRK--ALVIRDAKHHPLLDDVKKYISDIDLDTILVVPILSIGSLMVRTSSRELRFCQLVADASANAIKNASQVLEES
DE--------------LREIKEKLEAEKAVYESLFEHASEGLMVLNARGEPVYVNRSALDILGYQRDQMLKMTLTDFLAEE-SFQVGMENHMNFFLGRNK
YTKCGEKRCVAVSVSNYRLEGNY---AILTFMDVTEERRAQHLKSEFIYTATNDLRLPVAVIHSNCSQLRDSDTNNLMQREHLDSAIDSCDRLMDLIEEL
LDNSNFDSSELELSCEDKNIMESIQEVYTVLAPFAWQ-----HGLQMSVEPLQDNISAFFDSKKIQCVLTNLIGNAIKFTPSGGKIGISVSVCDEELLVS
VTDTGEGIPENYITRIFNEFYHLKSTNSSAKKGSGLGLAICKRIVDAHSGRMWVDSTLNHGSTFSFALPLS--------------
>tr|B9M874|B9M874_GEOSF Multi-sensor signal transduction histidine kinase OX=316067 OS=Geobacter sp. (strain FRC-32). GN= PE=4 SV=1
-TKILIVDDQKYARQMLRDILAPLQFVIEEAGDGREAVMKTMDFRPDIILMDLMMPDMSGIEASRLIKSTASIPILVITASKEKNNLLSAFAEGVDDYIT
KPFSTNELLARVQANLYKRDALIL-VEQKKTDAGII-LDL---------------SLSIASTLNAAKILARIAEHVN--MRRCSIVR--FSDSSHGHVLN
DDPSAKGLRIELSRYPELQEMIRTGK--AFVVKDAKRHPLLAEVREYIEDIDFDTILVIPIHHIGALILRTGSRELAFCQSIADAAANAIKNASLVLEES
DE--------------LRETKEKLEREKTVYEGLFEHASEGLMVLNAAGQPQYVNRSAAEMLGYSGKQMLKMSLKDFLAEE-SLQVGMENHINFFLGSRK
YTSSGEKRCVAVSVSNHRLEGNY---AILALIDVTRERRDQLLKSEFIYTATNDLRLPVAVLHSNCLQLRESDTENLTQCEHLDAAIESCDRLMDLIEEL
LDSSRFDLKDYALTIGKQNIMDPIREVYTVLAPFASG-----NGVQMTVTSLQSDIFGSFDGDKIKCVLTNLIGNAIKFTPRGGEIGISVDADDLELKIS
ISDTGEGIPEAYVTRIFNEFYHLKSAKGSLKKGSGLGLAVSKRIIDAHNGRIWVESSEDRGTTFSFAIPLT--------------
>tr|E1IA71|E1IA71_9CHLR Multi-sensor signal transduction histidine kinase OX=765420 OS=Oscillochloris trichoides DG-6. GN=OSCT_0222 PE=4 SV=1
--RVLVIDDDQGTCNLCAQTLGAAGFAVLTTPASPSALAYLNAEMCDLVLLSVDGPQQMGMTHLSQIRVVAAIPVLLLSRSITVPEIARMMRMGVEGLLV
KPFDPIELRDVALE-----------------------------------IITKQRD--ARARERVAALLLQVAGRLLAELDLSRL------QDL--IIET
VRSELRADRASLMLLEEDGTHIPPGITVGHRVAT--NQGLAGWVAQNRMCLCIDAS--GEVFPRGVFLEDQMTSSLAVPLNASKVLSGTSF-----SAAD
QDLLLLLAGQAATAITNARLYTQVAHSEARYRTLLHHANDAVLLLDAQARILEANLALEQLSGYTRDELLHLRPPDLL-----PEVGSLLRVGTETQEIE
QTRDAQPTRVAVSVSVVPYAGQ--QLLLVMARDISERQRITNQLLRLSASMAHEINNPLQAINNAVHLLLNRSLTDEKRQRYLEMTREEIDHLISIVQRI
LDFHRPSREGMR----PVDLVEILDGVLSLTSTQLH-----TQQIELIREIDPDLPHVLAVGSHMRQVCLSLIFNAIEAMNAGGELRVRAYLVDLFTIVE
ISDTGPGIPTQDLHKIFEPFY------TTRIKGTGLSLAMTYNIIEQHHGEMAVRSIPGQGATFRIRLPVA--------------
>tr|B9LH12|B9LH12_CHLSY Signal transduction histidine kinase, nitrogen specific, NtrB OX=480224 OS=Chloroflexus aurantiacus (strain ATCC 29364 / DSM 637 / Y-400-fl). GN= PE=4 SV=1
--HVLVVDDDPQLRDLCRQTLARAGFVVTTAADVTTALEALEQTVFDLVMVDLIMPGMNGLQLLELIRSRISVPILIVSGAASIEQISYAMRLGARGLLI
KPFRAQELADMARE-----------------------------------LVAKRQA--IRASDRLAALLLQISQHLLAELDQSRL------YAL--IIET
VRVEVHAERASLMLLEPDEQAIPDTVGIGALIPV--DRSISGWVVRHRQPLLIDQH--LVSSPKPHLLSPELTTALSVPLNAAKATLDAAF-----TAAD
QELLQLLAGQAAVAIENARLYSEVLRSEERYRALLRHANDAVLLLDATGMVLDANLALTRLSGYPGEEILRLNPCRLL-----PTLPALLSTAAEHSEIE
CTADGHETAVAVSVSVVPDGDQ--RLFLVIARDISERQRLARELARLATAMAHEINNPLQALSSTVHLLQHSDLSPERRDLYLTKAAAELDGLIQRVQRI
LDISRPNLDGRR----PVDLNQVVIDVIATYRQTLI-----ARNIRYIGELTSTLPWVTAVISHLKQVCQTLVQNAIEAMPEGGTLRIRTYLRASFWRLE
ISDTGVGIAQEEVPKIFEPFY------STRFDGLGIGLSLCYSIVDFHGGELWVRSQPEQGTTFRVILPIA--------------
>tr|B8G4R7|B8G4R7_CHLAD Multi-sensor signal transduction histidine kinase OX=326427 OS=Chloroflexus aggregans (strain MD-66 / DSM 9485). GN= PE=4 SV=1
--QVLVVDDDPQLRDLCRQTLVRAGFVVTTAANATSALAALDHATFDLIMIDLAMPEIDGLQLLELIRLRISVPVLIVSGVASVDQIAYAMRLGARGLLI
KPFRAQELANIARE-----------------------------------LVAKRQA--VQVRDRVAALVLQISQHLLTELDLTHL------YAL--IVET
VRVEVRAERASLMLLEPDEQAIPTTVGVGSLISV--AHSLSGWVIRHRQPLLIDEQ--VIASPRQYLLASELTTALSVPLNAAKATPHAAF-----TIAD
QELLQLLAGQAAVALENARLYEKLSRSVARYRALLRHANDAVLLLDSTGTVLDANLALGRLSGYSNEQLLQLDPNQLL-----PALSQLLATAYEQSEIE
CTASGHETAVAVSVSVVPDGDQ--HLFLVIARDISERQRMARELARLSASMAHEINNPLQALSNTIRLLRNPDLPSERRDLYLAKAALELDGLIHRVQRI
LDLSRPNLEGRR----PVDLNQVVNDVIANFRSTLT-----ARNIHYIGDCTSSLPWVTAVIGHLKQVCQTLVQNAIEAMPHGGTLHIRTYLRALFWRLE
ISDTGIGIAHEDVPKIFEPFY------STRFNGLGLGLPLCYSIVDFHGGELWVRSQPDQGTTFRVILPAA--------------
>tr|B1YN12|B1YN12_BURA4 Multi-sensor hybrid histidine kinase OX=398577 OS=Burkholderia ambifaria (strain MC40-6). GN= PE=4 SV=1
-AQILIVEDDRIVARDIAQQMSRAGYVVVGTGSGEEALALVETLPPDLVLMDVRLEELDGIDTARCIREARDIPVVFLTAYADEETIRRATAAEPYGYVL
KPFDDMQLRTVVEMALYKHGA-ERRLSEQRYAITLSSIGDGVLSTDVDGFVTFVN--------LAGEALT--------GWSRSEATGEVFS---LHDENT
HAPIMAAVLQTGSDGGLPARAILRARGGSDLPVECTGRDVTQKRTNARLEMAMY--GSNVGVWIGFARYSNIYEWL-GFDTPQARLDYEAYMSVFRVRGT
DAMGKVGSLVD-I-TELKMTEQALRASEERFRGTFENAAVGVAHCDLDGRFLRVNHRSGEIVGWPRDALQHRRLHDLIHADSIERFREGKLKHYSEEVPL
VRFDGERVWVTLSVALQHDASGQIIQDISERKALEETVRVAKDKDQFLANISHELRTPLNGILGYAQILQDVRLDTR-QLASVGVIEQSGQHLLTLINDI
LDFARLGAGKLELQVGEVPLRGFLETIAEIVAVRAQ-----QKRLVLNYVAAPDLPVVRVDERRLRQVLLNLLANAVQFT-DRGEVTLSVSRAAGRLRFE
VRDTGIGVSADRLEAIFQPFEQA-GDHTRRSGGAGLGLAISQQLVRMMGGEIEVTSSAGEGSVFGFEL-----------------
>tr|I4C9G5|I4C9G5_DESTA PAS domain S-box OX=706587 OS=Desulfomonile tiedjei (strain ATCC 49306 / DSM 6799 / DCB-1). GN= PE=4 SV=1
-PKILVVEDDPVISMLLRNRLAKLGYQIAAVSTGEEAIALAEKDPPDLVLMDIKLEPMDGVETACHLRTVLDVPVIYATAFTDEALLARAREAEPLGYLV
KPYGEKELRSAIEMALYKNRM-ERRLSEARFRNLSEAAPFGISVMAPDTSFEYFN--------PKFTEIF--------GYTTDDVSDTLFA---FPDNNY
RDRVRRETLSKGRMGEVPKNFVVTCKDGTHKMISFRTQDITAETTQWELTFDAV--SDCTMILEAMCQALKIEQDR-ALGRNCCEVVHGQTVSCVRIMGS
-----VYTARN-I-TERKRAEDKLRRANDLQQQLLATAATAIFIVDSGGKITEVNNEFCRMTGYSEEEAIGKTCRSFWGDQCALHLPKDIVK---VQANF
RAKDGRVLTVLKNASMMTNEQGEIVGGIESFIDVTDLIQ-ARMKTDFLTNMSHELRTPLNAIIGFSELLHAGEINDE-QSLYLGDVLDSAHYLLDLINGI
LDLAKVEAGKMELEASELQVVQLIEHSLTMIREKAT-----KHGLSISLNVDCGLELIQADEVKLKQIMYNLLSNAAKFTPDGGAISVGLRRTEDEVIVS
VTDTGIGLKAEDRERIFQMFEQVDSSYTRSEAGTGIGLALTKSLVNLHGGGIWVESEGGRGSAFHFTI-----------------
>tr|A7IA60|A7IA60_METB6 Multi-sensor signal transduction histidine kinase OX=456442 OS=Methanoregula boonei (strain 6A8). GN= PE=4 SV=1
-ISVLYVDDEPGLLEIGKLFLEDNGVCVDTETSARTALVTLEKTAYDAIISDYQMPEMDGLAFLVEVRKQFEIPFILFTGRGREEVVIEAINNGADFYLQ
KGGEPMELAHKIRQAVRRRKA-ERALE---------------------------------ESRDYLNLIFSSVKAGILVIDREQIVGKN----CHKYVCP
A----ETGKCPIT-DLGHSVDKILIT-AEPVTTVMLSGKLLETFNT---------------------QRKQAEKAYDELRMH---QEE------IQAAYA
ELAGN---EQILMHDTLIESERSLKESAEQFKTLFDSANDAIFVVSD-GVFVRCNARTRVIFGCSDSEVLGHSPAEFSPERSMERVRENDRAALEGIPLF
TRRDGTPFYTEVSLNAVE-IGG-EMCVQSIVRDISDRKRAEQAAALMNEFTRHEITNTITGLLGLVDMAYGMPAGE-GRDQLNR----EIKGLVVDIQKQ
VAFTKEYQEVGVKEPRWQQVREMIPTSSRP-------------GIHVSPS-L-DEVEIFADP-LVAKIFTYLAENVVRHGERATRITIGAEQHGSGLKVI
VEDNGVGVPEAMKAAIFEKKI---------GERKGMGLFLVREILGITGITIEETGTFGKGARFEIRVPE---------------
>tr|A7I520|A7I520_METB6 Multi-sensor signal transduction histidine kinase OX=456442 OS=Methanoregula boonei (strain 6A8). GN= PE=4 SV=1
-IPILYVDDEPSLLELGKLYLERTNFTVTTAPSASVALDRLKSNSIKAIVSDYQMPDIDGIEFLKRVREKDTIPFILFTGKGREEIAVKAFENGADSYIQ
KGGDSKELVQKLKVVVDHRRA-EVQVT---------------------------------TLHRLYTTLSATNKAIIHIHDKKELLSEICRLAWAGIANT
Q----THSIEPVA-IAGSDKGTITIS-TDPTGTAFRKKSVCNDINP---------------------WRKGALRSLAAFPFA---TGSRNAGVIIIRLLE
EQSGDISFALQTLDHQRRAAENHLKKSELQYRRLFETAQDAILILDGDGEVIDANTFILDMLGYPLEYFLGKHLWELGFLKNKSLAQDAFVRLKTQKYIR
ETQQGTPMHVEFISNVYA-VGE-KNIIQCNIRDITERKRAEDALALLSSITRHDINNQLQALSEYLELSKEVLADP-AASRYIA----NEERIAATIGHQ
IAFTREYEDLGVRAPVWQQLPEIIRLAGSQVP---------DNTIAFEFS-T-DHLEIYADP-LLIKVFYNLFDNARQHGGGVTRITISPHISGAGLIIT
VEDNGKGIPGEDKPHVFERGF---------GKNTGLGLFLAREILSITGISISETGVPGTGARFEIAVPN---------------
>tr|A7I8D9|A7I8D9_METB6 Multi-sensor signal transduction histidine kinase OX=456442 OS=Methanoregula boonei (strain 6A8). GN= PE=4 SV=1
-ISVLYVDDDSDLLDTGKSYLEQTQFAVVTASSGSAALELIRSNGIQAIVSDYQMPDMDGIALLQQIRAMNNIPFIMFTGKGREEIAVKSFENGADFYLQ
KGGDPEELMHKIKVAVEHRQA-DAQVT---------------------------------AVNRLYAVLSATNKAILHFHDKSKLLDEICRMAWAGFVNE
E----KHLIKNVG-TSGRIDGAIALS-TDPTETAFHTGTVCNDIAP---------------------WQKEALRSLAAFPFA---LNTRNAGVIIIRLLE
DQSGDISFALETLDHQRTAAKHELEESELRYRRLFEAAQDAILILDGEGEIIDANKFILDMMGYPLEYFVGKNLWELGFLKNKSFAIETFTKLKTEGYIR
ETRQGKAISVEFVSNVYL-VGD-KRIIQCNIRNVTERKRAEDALALMSTITRHDIMNQLMVLSGSLDLAQKSAKEP-QRTVHMN----RAKKAANTIQRQ
IEFTKEYEDLGSKAPAWQSLSGVVHSAESQLA---------PNPIILEIS-D-DSLEIYADT-LLEKVFYNLFDNTRKYGGAVTRISISHHPAVSGLIIT
IADNGIGISVEDKQRLFERGF---------GKNTGLGLFLSQEILSITGISISETGTPGKGAQFEILVPE---------------
>tr|A7I548|A7I548_METB6 Multi-sensor signal transduction histidine kinase OX=456442 OS=Methanoregula boonei (strain 6A8). GN= PE=4 SV=1
-YTVLYVDDEPDLLEISKLFLEQSGFSVDILPSAPEALAAMKVKTYDAIVSDYQMPGMDGIDFLKNVRALGTIPFILFTGRGREEVVIQALNEGADFYLQ
KGGDPTELTHKVLLAIEHRSN-AEKIQ---------------------------------SLNRLYLVISAIDRAIVQLRTKSEFLSEVCRMAWIGIPDP
G----EGIIRPVA-SAGQVEGIVRVA-LDPTGKAYREGKICNDIEP---------------------WRKEALNTCAAFPFG---RGSNNPGVLIISLTN
DLVADIAFALATLDHERESAIAALRESEEKYRLVVEDSRDAIYIHQSDLLFVNRQASVLT--GYSHEELLTIRLWDLVHPDDREILIRNNRDRLAGNPPP
LTKDGTSRTCEFVVDMVM-YQG-SPAIMGIARDITERRKTEEALASLSGITRHDIRNQLTILEGRLAFMKKKEPDS-PFLEHFE----KMSAAARRIASI
IQFTKEYEDIGIRAPAWQDCRTLVDTAAQQVH---------SGQVPVKNDLP-PGTEVFADP-LIVRVFYNLMDNAARYGGKITFIRFSLEGSGNDYRIV
CEDDGEGIPAEDKEKIFLQGF---------GKNTGLGLFLSAAILHITGITIRETGEPGKGARFEIIVPK---------------
>tr|B8GG07|B8GG07_METPE Multi-sensor signal transduction histidine kinase OX=521011 OS=Methanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c). GN= PE=4 SV=1
-YHVLFVDDEPMLLAIAKLILEETGFFITTITSAPEALAIMESVPFDAVVSDYHMPLMDGIQLLKEIRVTYDLPFILFTGRGREDVVIEAINNGVDAYLQ
KGGDPTELAHMIKKGVERKRA-ADALK---------------------------------QDESRLETLVSFYQMVDAPLR--ELMTRAIEIGYLAFVEE
E----ETMMTMYA-WSSE---MNQCT-IRLWGEAVRQRRITNDYNP---------------------QKKGYPPIIRHMNIP---IIDDD--HIVGNKRS
DYDERDLRELSLLTQKQRRAEASLRESENRLHLALDGAGWDWYIPSGNAYFSLQYYT---MLGFEPRDFPPTFESWTSLIDEQYKVTSDLLKQIKERRST
RTKDGDERWIDARGKAIE-WDE-ETRVIGINADITGRRKTEIALRQLSGITRHDILNNVTVILGYLGMAEVKCTDP-DLEKYLK----KMKLATRAIQAQ
IGFTRIYQDLGTNEPQWQRLEAILSKLQ--IP----------PQITLTIG-L-QGIEVNADP-MLEKALFNLLDNSIRHGQQVTRIQVSSRQEGENLTIV
WEDDGVGIPINEKDQIFIRGY---------GKNTGLGLFLVREILSLTGITIRETGIEGEGVRFEITIPK---------------
>tr|Q2FM18|Q2FM18_METHJ PAS/PAC sensor hybrid histidine kinase OX=323259 OS=Methanospirillum hungatei (strain JF-1 / DSM 864). GN= PE=4 SV=1
-IRILLLDDEPAVLDITSAFLNRQEFRVRTIDSVKGALMLLSEYPFDVIVADYELPDQDGISFLKQVRSSQSIPFIFFTGRGSEDIAIDALNEGADFYLK
KGDGSVKLARYIQKAVEKRRK-QDEII---------------------------------LNEHRYRELAEQQMEYAQYIQ--ALLDAIPARDTNGVYRD
C----NKAFEDL---IGHRKYIIGRS-VHPLADHYRHMDIIKN--P---------------------Y-------IQQYEYV---ITDSQGEIHSKSALL
SHEGSVTGIIGVILDERKKLERIIIENEEKYRTLADFTYWESWISPT-GTYIYTSPSCERITGYRAEEFLHNPGLVLEITDDRQMVERHYSNAPLHDGIH
ITKDGQERWISFCQSVFR-DDG-TLGRRESKRDITFRKEVTAAYEKLSSITRHDILNQLTVLSGYTDLLSDYADNP-DIHAILN----RMNRTIDTINNQ
ISFTRLYQEIGVNAPQWHHVPTLVRQAGKGSH---------IPCIEISEN-L-SDIHILADP-LMEKVFYCLLDNSERHGKRVSRAHFYCYHTDGDMTLV
YEDDGYGIAAGIKEKIFERGF---------GSNTGYGLFLAREIINISGYSIFETGESGEGARFQISIPK---------------
>tr|G6FL30|G6FL30_9EURY Multi-sensor signal transduction histidine kinase OX=882090 OS=Methanolinea tarda NOBI-1. GN= PE=4 SV=1
-MRILLVDDDPMLPDLIQKFLEKEGIEIEATRSGSEALEKISQEKFDAIVLDYELPGMNGIDLLRMIKRRGDIPAIIFTGKSREEVAIRALNYGAEYYLQ
KKGDPRELLSMIREAVRKHRA-GLELK---------------------------------ESERRFRESLENARLIAFQLD--RNLFVIFCLGIAGYRRE
DVS-GRSFVELFV-AEGERQKMFFSA-IRYFTCSIRTAKTRR----------------------------------IALNCS---VLKDSSGNSIGQ---
--------------DEKEKAEEEKAESEERLKVLFEYAPFPYFITDLKGTFLDGNHAAELLVGYSRRELIGRNFLESGLLEEVPKAIALLAKHIRGEATG
IRKDGSLVVAEIRNQPVR-VKG-QTLVLGSVHDVTGRNAAEESLRRLNIITRHDILNTVTALLLYIELLKESPKDD-AQKETIS----RIEMLAQTIKRQ
IEFTKVYQDIGMGNPQWQALGPIIERVKNSIP---------LPGVTVSHD-T-GGIEVYADP-LLEHVIHNLIDNSLRHGNGVSSIWITTLQDEMGLKIV
YEDNGQGIPPREKENIFKRGY---------GKNTGFGLFLAREILGTTGLQIKETGTYGKGARFEIRVPR---------------
>tr|A7I541|A7I541_METB6 Multi-sensor signal transduction histidine kinase OX=456442 OS=Methanoregula boonei (strain 6A8). GN= PE=4 SV=1
-IRVLLVDDESALLEVSALFLESSGITVKTVLGAPEAMQLLERERFDVIVSDYQMPVMDGIEFLTEVRRHFQIPFILFTGRGREEIVILAIDRGADSYVQ
KGGETKELAHKIRMAVKRRVA-ESQTA---------------------------------ESKEFLKNVIADAKEGIIVYDRDLRIML-----WNRFMED
L----TGL---------------------PAAEVLGKNTLF----P---------------------FHTENGMKQALTGIT---TETQDFAFVVFSPNY
DLSGAIKGVIGIVRDERKQAEVALQESEERYRKIFENSPLGMILLTPDLRFFRVNPALAAMTGYSEEELPGMSFADITHPDHLTSDRQSLEDLTAGKIPA
IRKDGSVMSVRVTSILDD-HAA-LKYYAAQIEDITERRLTAEALRTLSGITRHDIANQLLVMSAYVSLLNDQQPDP-AAGEYLG----KMDRSLTRMNDM
IGFSREYEKVGVAAPVWQNCHSLVDIAAKQIL---------MGDTIVKNDLP-PHCEVFADP-LIFRVFCNLIDNAMRHGKTITTLRFSVADRAGSRVIV
CEDDGVGVPAEEKEVIFEQGF---------GKNTGMGLFLSREILDITGITIKETGEPGRGARFEIILPP---------------
>tr|L0HDB0|L0HDB0_9EURY PAS domain S-box OX=593750 OS=Methanoregula formicicum SMSP. GN=Metfor_0001 PE=4 SV=1
-ISVLYVDDEPGLLELTKVYLEQSDFEVTVLPSAALALKHLKTRSYDAIISDYQMPGINGIEFLKQIRKTNGIPFILFTGRGREEVVIEALNHGADSYLQ
KGGDPKELEHRIRSHVQRKWA-QDALS---------------------------------ESEKKYRRVVENAHEGIYIIQDERII------------FS
N----PHIIERIT-ECGISEAFLSK----PFFTFIHPDDLMRD--R---------------------YYRRIEESFSRYPFR---MVNSSGAVYIYAVVI
DWNGR-PATLNFARNEQYSLEERLSDSECRYRELLDLLPKTVIGMDTEFNLTFINRSGEEKWGYANGEILGKAITDLIAEADRGRIRNALLKATEGERIT
TLRNGRTFPVKYLSPMIR-KSN-IAGFLAVCVDISDFRDARTMLAYMGKINCHDLHNQLTILDGYLALAEKKTKDQ-DVLRYLH----RIGNATKTIRIQ
MSFMEQYMKIGSSVPLWQNIEELISNIHPDLL---------SGTIRIDID-L-GGLEIYGDL-LLEKVLYNLFDNAIRHGGHVTAIRISFDNTETGIDLV
FEDNGIGIPESEKKKIFTCGY---------GKNTGLGLFVIEQILSISGITIAETGEPGKGARFVMHIPA---------------
>tr|Q2FRM2|Q2FRM2_METHJ Multi-sensor signal transduction histidine kinase OX=323259 OS=Methanospirillum hungatei (strain JF-1 / DSM 864). GN= PE=4 SV=1
-ISVLYVDDESDFLFLGKNFLNKEPITVDTVTSAQEALTILKTRTYDAIISDYQMPVMDGIQFLQKVRSLYRIPFLLFTGKGREEVVITALNSGVDFYIQ
KGGDAFELAHKIRQAVERKRA-EDRLI---------------------------------ESDRRFRKTLQTMKLIAFQLDDGKVLF-------C-----
N----DHLLHL----TGWRREFMGRD-F--FEMAVPEDLLKKH--S---------------------FQEALKSQHEEMKLL---LRNGEIRDIMNTDLR
DEHGGLIGYMCIGDDDQKIAQKEVEAWRNRYKMVTTSSGLVVYDYDMKQDQIIMSENVSDVFGYAYNEISGFQWLELVHPDDRKAALDAFYSVHTGDVVR
RHADGHYVWVEDRVSVPD-IID-SYRLMGIMADITRQQEAEEALRLLSSITRHDITNSLSAMQGYLSLMEECEPHE-I-PEFTK----KLRDISVSIESQ
IAFSREYEKVGVSEPDWFCVSDILKNLPFEYI---------RLNCEV----P-SNLRIYVDP-MIPKVFYNLLINAKNHGKHVSTITVSCRNNDSSLILS
WEDDGIGIPHEEKDLIFTYGY---------GKNTGYGLYLISEILKITSITIYETGIPGKGARFEIVVPF---------------
>tr|B8GIZ0|B8GIZ0_METPE Multi-sensor signal transduction histidine kinase OX=521011 OS=Methanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c). GN= PE=4 SV=1
-IRVLYVDDEPGLLEIGKLFLERERFVVDTLTSARVALEQLNSERYDVIISDYQMPEMNGIQFLVEVRRRFQIPFILFTGKGREEVVIQAINCGGDFYIQ
KGGEPGELANKIKQATSRKKS-VDSFR---------------------------------ENEDDYRYLIEHSNESIVVVQDDMLR------------QV
N----HRIVER----TGYSEQLLSI----PFFALIHPDDMTVE--R---------------------FHKRMMETPSKYSFR---LTGKDGSTIISAVTI
TWEGR-PATMNFLIDGRKQTEEALRNSEVRLHTLVDTIPDLIWLKDTKGAYLSCNPMFERFFGANESEIVGKDYDFLDRKLADSFHEQDLKAMVSGRPIR
FADEGHCALMDIKTPMYNDQGA-LIGVLSIGRDISERKRAEDAIELMNNITRHDILNTITGLLGCVDMANVTDSED-ERRQLFQ----DIKNLTKSIQRQ
IAFTKEYQEVGVNLPAWQNVEDLLQRILINFK---------QSGKQFIID-L-ESVEIYADP-LLEKVFHNLVDNAIRYGKNLTTIKFFLVKSNNGLSLI
CEDDGPGIPDDIKCYIFEHGV---------GNNSGMGLFLSREILGITNIGFWEDGIYGKGARFEMFIPH---------------
>tr|Q2FRH3|Q2FRH3_METHJ Multi-sensor signal transduction histidine kinase OX=323259 OS=Methanospirillum hungatei (strain JF-1 / DSM 864). GN= PE=4 SV=1
-FSLLFVDDDPEICSIAKTFLEKTGFKVTTSESVKKSKRLLKKYHYDAIISDFDMPVTDGLTFLRSLRSKGKIPFVILTGKGNDQVIIDALNSGADLYFV
KTDSPKQLSEKLIPLIRSKQA-EI----------------------------------------IFHEIFTQSPIAIELFNDGKLLQVNKALDLFGVVHQ
KE---IAMFDLFQ-DPNVPEG---------ALKQLKTGE------E---------------------YSTSFDQQHTLYKTT---KTGQIDIHVISLSYP
DITGG---YLVQIQDEQKKSEMALKSSEERYRSIFSNNHSVMLIISPDGAILDANPAACSYYGYTHEELTHMDITRINCL-SRDEIFQEMERARKEERNF
RLASGEIREVEVHSGPIV-LDQ-AQVLYSIIHDITEKKRIEDALVTLSSITRHDILNVLTALTGYLEFAATETSIE-EARIFIQ----KSQVAARSIRHH
IEFTRDYQDLGSKEPVWHDIRAVLKNSAALVN---------TRQVSIEFDTD-TRLVVLADP-LLLKVIYNLMENAIRHGGTVTRITSSSRNPDHSLSWI
IEDDGVGIPPSMKKHIFSREV---------GKNTGLGLFLAREILAITGITIEETGTEGKGAQFIMRIPE---------------
>tr|K9S8G2|K9S8G2_9CYAN Multi-sensor hybrid histidine kinase OX=1173025 OS=Geitlerinema sp. PCC 7407. GN=GEI7407_2018 PE=4 SV=1
--NILLVDDHPENLLTLEAILADLGENLVKAHSGQEALRCLLEQDFAVILLDVQMPELDGFETATLIRKSRQTPIIFVTAFSTSNNVFKGYSLGAVDYLL
KPLEPAILRSKVNVLYRKT----AALERQARQLTQRELQVANSQDLEQRVLQRTASLESEIRDRKQALLATMAANLGMWFWDLATGEIVFGLDLFGVQGQ
TSMTYPEFVAKLHPLRSRQEYNEAARGRGLYNAEGQAV-----------------QMMG----------------------VVLDITKRKATEAALRQSD
ERFRQFADNIQ---DVF--WIFELAEDQKRLLYVS------PAYEQIWGRSALYDDY-HEWLDAIHPDDRDRVMLFLCEN--------MVRDEFSVEYRV
IRPDGSIRWVRDGFPVRDAQSGEVVRVTGITEDITDRKQSEAEKDEFLAILSHELRSPLNPILGWAKLLRSRKLDEATTHRALETIERNVKLQAQLIEDL
LDVSRILRGKLVLNQTHVTLPSTIEAAIETVQLSAD-----AKSISIVSDLDTTLGPVLGDPNRLQQVIWNLLSNAVKFSPDGSTVTIRLRRVDEYAKIE
VIDTGRGIKPDFLPYVFERFRQADSTTTRVFGGLGLGLAIVRYLIEMHGGAVWVESQEGHGATFTVLLPL---------------
>tr|B4CZ63|B4CZ63_9BACT Multi-sensor hybrid histidine kinase OX=497964 OS=Chthoniobacter flavus Ellin428. GN=CfE428DRAFT_1951 PE=4 SV=1
--SILLVDDDPKNLMVLETILNSPEYRLVNASTADEALLALMNEEFAAIVLDVQMPDMSGLDLARLIKQTQHVPILFLTAYYQEDEVVLGYGAGAVDYIT
KPVNPAVLRSKIGVLFRKT----TALAEVNRAMEMAERQQAEERTAPNAMVSRTEDAEDGLHDFETSVGTTIPLEVGLSQFQSSDG-------IFKLASF
VDITERKRAEAALRRRQAEDRVRAARERSSFLAEASSV-------------------LA----------------------SSFDY-------------G
EMFTGLAQLLI---PNFACCIVDLVQEDGTLKPLV------VAHKD---KAQQINEF-RRAFPARLEDGRGVAIPVLCKQ--------FGEKQMAAFARS
PEEEAALRPLEISYIVRGRTLGGLCFASSLAIELAERAGMALDKDRFLAMLSHELRTPLSPVLHATTLLEEADCPEPM-RSTIATIRRNVQLEARLIDDL
LDLARIRNGKLQLQPEPVDAHDLLARAVDICRPDIE-----TRQLQLTVDLHAKRHSLEADPARIQQIFWNLISNAVKYTPPGGAISL---RTEDSLRVE
FTDSGIGIESARLESIFDAFEQANSGRS---GGLGLGLAICRALVTLHGGRIEARSGASRGSLFVVTLPT---------------
>tr|K9XT60|K9XT60_9CYAN Multi-sensor hybrid histidine kinase OX=111780 OS=Stanieria cyanosphaera PCC 7437. GN=Sta7437_1704 PE=4 SV=1
-DQILIVDDTPTNLEILLDLLENSGFKVVVSEEGESAIEMAEYAPPDLILLDILMPEMDGFETCKMKPTTKDIPIIFMTALSDRVDRVKGLNLGAVDYIT
KPLEHEEVLARVNIHLRLQNL-TKRLTEQNAHLQ-QEI--E---------------KRSEARFRRL----------------------------------
------------VESNIIGIICSHLNGKITEANDAFLKI----------------------------------------------------VGYDRNALQ
MGSLSWHEMTPSEYQHLDLDLTEHKQAQQKIFALLDITTDAILVRDLDNKIRFWNQGAERLYGWKASEAIGKNANELLYREQANQLPDIQASLTENGSWQ
DELSNQEIIVSSRWTLVRDDEGQPKSLLVVNTDITEKKQLEMQFRTLASGIAHDFNNILTMLAV--SQLLPLKLPDLQSKNLLKILETSARRGAALVKQI
LSFAREEEGRKH----RVQVRHLLSEVAQIAQQTFP------KSIEVIKDVPSNLWTVWADATQLHQVLMNLCINARDAMPNGGTLTIAAENVGSYIVIS
IVDTGTGIRPEILERIFEPFFTT-KE----LQGTGLGLSTVLGIIKSHGGFLKVYSELGEGTQFKVYLPAS--------------
>tr|Q2FUG6|Q2FUG6_METHJ Multi-sensor signal transduction histidine kinase OX=323259 OS=Methanospirillum hungatei (strain JF-1 / DSM 864). GN= PE=4 SV=1
MYQVLCVDDEEFLLELCKLFLERSGLKVDTALSASDGLERLKEKEYDAIISDYEMPGMNGVEFLKEVRSFENIPFIVFTGRGREEVVIEALNNGADFYLQ
KGGDPKAQFAELKSKIKQKHAEKIYVNKNQNFLGHCEF-CTNSIIFPYSWEHWPDGSSEDELKHQFQELNESREHLERYSVIENTQDVFYRSDI------
-GKNI---ADIFYQNSDEYDDKST-----AFAGVEGTRDISLERFLVEHIEDGVFIVL-IVFCFANIIGYSLGSPEDELI-W-KCHNSKEYDFRFLHKDK
KTSVIISGTIHHADR-LEQVENSLRESRAMLNAILQESPIPQFVIDKNHKVVYWNQALSVYSGIPSNEVIGTDIADLILDGRIDELDVWYKGNAKQSTLV
FSHLGEHGYF--TGALLRDSNGDIWGALETLEDVTEQKMNEEGLRE--ANTRHDILNMLTVLTGAIDLIRDEIS-D---QAVS-FYLQPVDKALDTIYRQ
ILFTRDYQNGI-TSPVWQSLSAIIEETIIRVLP---------KEIRFIQNN--TNYDIYAD-AMLGRVFANLVDNTLRHGGTVTEVRVSAREEQNLLYIF
YADDGKGIEDSIKEQIFNR----------GFSHTGYGLFLVREILSITHCTIQEVGTAGKGVVFEIHVPF---------------
>tr|A7I5Z7|A7I5Z7_METB6 Multi-sensor signal transduction histidine kinase OX=456442 OS=Methanoregula boonei (strain 6A8). GN= PE=4 SV=1
MISLLYVDDEPALLDLCRLFLEQEGISVSTAGSVEEALARIAAGTFDAIISDYQMPEIDGITFLRTIRRQPDMPFILFTGRGREEVVIEAINSGVDSYVQ
KGGDSRAQFKELSHLVRRRKAESGYFNEACAMLGYVDIRGLSRQSLSSAWDRKKDGQMEDDLHRQFEDLKKSDHAMQRYMLSAVSKDWIWEIDA------
-GKCF---SDLLVPACALKEGRLTHSAEGTFCGFYGIRDILLSRTLLEQAGDAIFVTNALNLVLPEVCALQYSPRSG------DEPLRLRDNEVLVDKEG
NPPVIVSGIYHDISD-LRSIESALREKAGELDRFFASGPDMFCILNTDGRIVRLNPAGEALLGCTTGPGAEHSLPELLHPDDRADLHYLLMHMGSGGKAS
VQPDGSSRWL--EWRAFLSEKNQIYAIA---RDFTGQKRAEQALAL--ANTRHDIRNKLAVLTGYLDLFRSCPA-E---PYFS-LYTEKINETVAAITAQ
LEFIRIYQKGS-AEPAWFNVNQVFSGACRQREI---------PAVIVSSSP--DSWEIFAD-PLIDRVFSTLVDNAFRYGATLTKIQRSAHESPEGLVVV
IEDNGIGIAQEKKEQIFEK----------EAKACGHSLFLAREILSITGITLRETGRAGKGARFEMQVPK---------------
>tr|B8GJB1|B8GJB1_METPE Multi-sensor signal transduction histidine kinase OX=521011 OS=Methanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c). GN= PE=4 SV=1
MNTLLYVDDEPALLELGKIFLEFTGFVVQTASSVLEGIEALRCRSFDAVVSDYQMPEIDGISFLKQVRSLGDLPFILFTGRGREDVVIEAIKNGADFYLQ
KGGEPRPQFSELTNQIRRRRAEISYVSPSTKILGLAELIAEDSVFFPGDFERMPDHSGVQVQGRDITDQKRAEEALRRLALFSAMTDQILTLDL------
-GKTV---HEVFPQNLADLEKKSRESLKAAYEEIAASEEMALNRTIFEHTGTAMVQVLAISLVFEDITGYSEGVPGDRVLAY-HRAISAPLRFRFVRQDG
GESILSTASLVDITA-IKNLEGELRASEERFRMLFEHAPVAYHSLNPEGRLIAVNQAWLDEMGYTREEVIG--FSELVVESSREHFKNLFSRLVDRRQIR
IRRDGTQ-FL--ALCEVTAAYGRNMGLKQVIINRSERMQVEQALRQ--ANTRHDILNQIMVIQAYLDLLDEEVR-P---EGTS-TILTKLNGATGAIKNQ
IEFTRVYRDGY-HPPHWHPLVDLLPT---QDLP---------ENIRFTTSV--EGIEVFAD-QLMAKVFFNLLDNAMRHGERVTEIRFSAGRQRENLVLS
WEDDGVGVPVREKERIFER----------GVKNTGLGLFLVREILAITGITIREAGTPGVGARFLITVPK---------------
>tr|B8GJZ1|B8GJZ1_METPE Multi-sensor signal transduction histidine kinase OX=521011 OS=Methanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c). GN= PE=4 SV=1
MITLLYVDDEPALLSLGKVFLERLGLNVETIQEPELALEMLAARHYDAVISDYQMPEMNGIELLIEIRKRNKLPFILFTGKGREDVVIEALNNGANFYLQ
KGGSPHAQFADLSNMVEQNRA---VRATEKQLLETCRV-IIEEGSYQFTWVGWAGDSLNTVKPAVSRKLPGNNETVALLGFAASISVPLHSGEV------
-KLGV---LKIYSDQPDAFD----QEEVALLTQLAADCAIHAERIIFEYSGTAMLFIKTIALVFSSLSGQTEGDSDDKMEQY-HDLRRKNGHARFISSNG
EVTVILTASLIDITE-QKMAQEALLERENWYRAMINDQTEFICRFLPDCTFTFVNEAYCTYFNRTYDQIIGQTFTPVLYKDDIHRVQDFFKSLTPEHPVG
VMSSGEVRWS--DRAIFDKAG----NVLEYGRDITEQKLAESALEL--ANSRHDMLNQLTAIQGYIMLAQDNSP-P---PAVL-IPLTQADLGCQNIREQ
LEFTRDYQEGT-KRPGFMNVRESLMRGIAQIDI---------NDLSFTLAL--GDLEVYSD-PLLDRVFYNLVENSIRHGHHVTEINISALPCEQGMMIV
YEDNGCGVQEKQKELIFSH----------GFKNTGLGLFLIREILGMTGIKIRETGKENEGVRFEITLPN---------------
>tr|A7I5B1|A7I5B1_METB6 Multi-sensor signal transduction histidine kinase OX=456442 OS=Methanoregula boonei (strain 6A8). GN= PE=4 SV=1
MYRILYVDDEPGLLEIGKLFLDSTGFDVSTLTSAEKALESPEILLFDAIISDYQMPGMDGISFLKNIRKRKDVPFVLFTGRGREEVVIEAINSGADFYLQ
KGGQPTAQFAELAHKIERRRAIDSAWNRAEQMTGTAED-IRGKGNYEDGMAFFSFEGPVQIRGNSLRYLWGIAGRLGKCGSIESIRDITERKEA------
-EKEL---QAAY-EQIAAAE----EELRGQYEELAAG--AQLA--IFKEAPHAIAISTGKYLVFEQGSGLALGPEEHLLKEFEGGIRQKPLT------DG
RKDILFTTMVVDITD-MKRIEDALRKQEQILNDAFASIKDGISLLDKTMTVIRVNKTMEEWYSHEM-PLIGRKCWEVYHRAGPCDICPTLHTLKEGKPAK
LVDAGEVTLY--SYPVIDSATGEMTGVIEYVRNVTEETKAQRDLEL--ANTRHDILNTLTGLQGLVDKAASLST-S---GECT-HLLSQIRDRAGIIRQQ
IDFTGRYQEGV-HAPLWQDVNVLLSRILPATPR---------TKAGIVNDC--DNVEIFSD-PLLEKVLYNLVNNALKYGPDLTTVHITSDLSAPELIIA
VADDGVGIAAGDKDHLFQR----------EVQKTGSGLFLAREILSITGITIRETGTPGKGARFEILVPP---------------
>tr|J1L4C0|J1L4C0_9EURY Multi-sensor signal transduction histidine kinase OX=28892 OS=Methanofollis liminatans DSM 4140. GN=Metli_2000 PE=4 SV=1
MLSVLYVDDEPALLEIGKLFLQRSGFVVSTCESAPDAIRLLSEASFDAIISDYQMPGMDGIQFLQHLRQHNTIPFIIFTGKGREDVVAEALNSGADFYLQ
KGGNPKPQFAELSDKVARRQVEEE-------------------------------------------DLAVAQQEIEQFQLFESMDEGMALHEI------
-GKLS---RDAYGTDEPPFEFRPRNQFATIFEDITGRQKEALKRNLVENLNEIFYVLATITYIIESIGGYPIGHPEDRILQF-RSILSGSNEYRFLKADG
GSWVKTAGMLTDITS-LKMMEAGLRESEEQYRDLAENAPIGILTCDTEGRITYVNQRGLEILGSPGEEETRRIFPSLVRIGFAEMLRKTMDSGRPIPAIE
CTKWGKAAYY--RVHFSPILYGTITGARIILDDISEHKKAEGALNK--ANTRHDILNQIMVIQGYLDLAKDVDK-D---PALS-EFCGYVGRAAAAIQRQ
IEFTREYEQGL-KEPTWLSLGGLIEE---SDDP---------R-LPIRHEC--RGISIYAD-PMIEKVFSNLMDNTIRHAEGATGVQIRCSKSGSALMIT
WEDDGPGVPDDQKGRIFER----------GFKNTGLGLFLAREILGITGIAIAETGVYGEGARFEMLVPE---------------
>tr|Q1DFG3|Q1DFG3_MYXXD Sensory box histidine kinase/response regulator OX=246197 OS=Myxococcus xanthus (strain DK 1622). GN= PE=4 SV=1
--GVWVLDDSPVES-QAICRALEPYCKVTGFLDGASLLESLTGPVPEVLVLDWHLPGMSGLEVCRFVRATEHIPVLLITGNTRAEDVVEGLSAGANDYVF
KPFRPVEFAARVQALAQWERSRRKTLEDERA----WELRFRLARATRDAVWE--------------------WDPRTGLMDWTSGLHEVFGIRRWWEER-
LHPDDRRVVASLQATVEGPEYRFQ-RGDGSWVACHIIRDAQDNATQVVGAM-------------------------QDVTERHE----------------
------------------AEAARAREESDRQRAMLATVPLGVLS-VPDQRCVVANARLRQRFG--QRQLVGRTLREALPELEGQNVLELLDTVFATGSAR
VRIAQVEG----YFDFMYQPSGRLILFAVEVTDSVLARHKEQQMKQLIGIVSHDLRNPLGAISLAVSMMLRGLLDE-RQARQAQRIRSSADRATRMIRDL
LDFTRARQGTGPVYPQPMDLHEVVRTVLDEVHA-G----WPDRHLETERT--GDGVGTW-DPDRLAQLIGNLVGNALQYSPPGTPVRVTSRGDDDGVVLE
VHNLGPAIPLERQPRIFEPLERATVRPEDQRRSIGLGLYIVRSIVLAHGGTVEARSQEETGTTFTVRLPRH--------------
>tr|J2KFT9|J2KFT9_9DELT Uncharacterized protein OX=1192034 OS=Chondromyces apiculatus DSM 436. GN= PE=4 SV=1
--MVWVLDDSPVET-QAICRALEPGCQVTGFMDGPALLEALTRPAPEVLVLDWYLPGMSGLDVCRFIRATEQLPVLLLTGNTRAEDVVEGLTAGANDYVF
KPFRPVELAARVQALAQWERSRRKALEEERA----WELRFRLARATRDAVWE--------------------WDPRTGLMDWTTGLHEVFGIQRWWEDR-
LHPEDRRVVSGLQATVAGPEYRFQ-RGDGTWVACHIIRDANDRAIQVVGAM-------------------------QDITEHQQ----------------
------------------AEAARAREESDRQRTLLATVPLGVLS-APDQRCVVANARLRQRFG--ERPLVGHTLREALPELEGQGVLGLLDSVFATGSAR
VSIAQQEG----YFDFMYQPSGQVILFAVEVTDAVDARRKEEEMRQLIGIVSHDLRNPLGAITLAVSMLLRGPLDE-RQERQAQRIRSSADRATRMIRDL
LDFTRARQGTGPVYPQPMDLHEMVRSVLDEVHA-G----WPERKLETERT--GDGLGTW-DPDRLAQLIGNLVGNALQYSPPGTSVRVTSRGDADGVVLE
VHNQGPPIPPERQSRIFEPLERATVRLEDQRRSIGLGLYIVRSIVLAHGGTVEAHSSEAEGTTFTVRLPRH--------------
>tr|Q09DL9|Q09DL9_STIAD TodK OX=378806 OS=Stigmatella aurantiaca (strain DW4/3-1). GN=STIAU_1463 PE=4 SV=1
--TAWVVDDSPMEA-EAVQRVLEASGDVEIFLDGATLLERISAPLPDVIVLDWMLPGSSGLEICSFLRDEAELPILLLTARGAKADVVEGLSAGANDYVS
KPYAPEELAARVSVLVRLRRAHLRALRAES------ETDYRRTDNLPDVVSR--------------------IDHQHRHLYVSPSVTRLWGLPYLGKTT-
VELGMPNQVAAWNAAVDAALMHFDLSSRGGLFHVVPERDEEGNVVSVLCIA-------------------------RDMTSQVR----------------
------------------AEQA-LRESEERLRLALEV--IGTWDSDPRTLELTCDARATVLFGLKERKAHPDHLYEPLSPEDRERVRAEVDKALVNGASE
LAADGIER----WVSVQGRVQGQAVRFLGTVRDISEGRRQEEEARKLVAIVGHDLRNPLSAIQVSAA-LLRKLGEP-SLLRKLHVISTAADRAGHITRDL
LDLTQARLGGGPVRPQPCELHAVIREVAEEHHA-A----HPERDIRLDLA--GTAEGVW-DPERLAQVVANLLSNALNYSPPGTPVEISSQRHEEELVLR
FHNQGPPIPEEMRSRLFAPFKRRPERSAGPRDGLGLGLYIAERIVSAHGGHIGVDSTELQGTTFFVHLPWR--------------
>tr|J1SX77|J1SX77_9DELT Histidine protein kinase AsgD OX=1192034 OS=Chondromyces apiculatus DSM 436. GN= PE=4 SV=1
--SVWLVDDSPTHL-ARARELLSRHYAVETFRDAEQMLGRLSRQPPEVLLLDWQLPGISGLAACRAVRDEVSLPILVLSHPGTVADFTEGLQAGANDHIA
KPYHDAELLARVASLQRI-RAQSERLKER-------EAYLFTLASIGDAVIT--------------------ADRAGRVVLLNPAAERLTGWTAWQHPA-
VEVCDATRVPRVPALPFDEATLLL-RKDGTEIEIAPIRTSPHDISGAVLIF-------------------------RDVTAQTQ----------------
------------------VRERNLRASEAEQATLLDAIPVSFV--NADERYGRVNKAYEEWFGISQDGLRDQKIRDVIGEAAYAVMSPFVKRGLAESEQH
YRLGGKDV----KVSFIAHSPGA--GYVALLQDITVERKLERRLQQLIGIVSHDLRNPLGAIHLGAERLKKEALAP-SAIRTVDRILESAARAVRLVREL
LDFTQARLGGGRIERAPMDLHALGRTALEEVEE-A----NPAARVELTTR--GDGRGAW-DADRLSQVLQNLVMNAVKYGQPGAPILVEIEGDGDPVTLR
VHNEGPPIPPERLQGLFQPLQRGSDAVDVTSRSVGLGLFIVKAIVDAHQGHIDVRSSRGEGTTFTVSLPRQ--------------
>tr|K9XCJ4|K9XCJ4_9CHRO Multi-sensor hybrid histidine kinase OX=1173026 OS=Gloeocapsa sp. PCC 7428. GN=Glo7428_0778 PE=4 SV=1
--YILLVDDNADMRNYIKRLL-SQTYEVVAVSDGVAAIEAIAQRLPDLVLSDVMMPRMDGLELLRQLRNTAKLPIILLSARAGE-AQIEGLEAKADDYLT
KPFSPRELLARVRATLELAQVQQAAAALEQSEKRYRTL----ANAIPQLVWMSNEGLVTYINQRWQEYTGLLSQSMGL-----NWLELVHPEDIPHL---
VKMRNRGIR---ASEAYEIEYRIRRFDQTYILSWFGTATDIHDIKQVEAAQRFLADASSIPFLYCFF--DIVDREIQRVAWQHKDPAKQQWFDRVQNSSG
KPYF-----VPVVSDEWLQAIATTPQHLLRACEIRSWMTVALVVQQRRL--------GTLTLCLSK------------DSSRDYTETDL-----------
----------------------------RLAEELAHRVALALTKDQFLAVLSHELRSPLNPILGWSKLLLTRKQDEATLIRGLETIERNVKLQAQLIDDL
LDISRILQGKLTLNIGWVDLKRAIAAAIDTVRFAAA-----AKSIELETSFAPKVSKISGDASRLQQIVWNLLSNAIKFTPEGGQVKIKLEQIDSHVQIQ
VTDTGKGIAPEFLPYVFDYFRQGDSSTTRQFGGLGLGLAIVRHLVELHGGTVQATSLIAQGATFTVRLPI---------------
>tr|K9XKM3|K9XKM3_9CHRO PAS/PAC sensor hybrid histidine kinase OX=1173026 OS=Gloeocapsa sp. PCC 7428. GN=Glo7428_4750 PE=4 SV=1
--RILLADDNADMRNYVKRLL-SQRYTVETVPDGIVALNAIKQNPPDLVLTDVMMPKMDGLELLQALRATREIPIILLSAQAGEESRVEGLAAGADDYLT
KPFSARELLARVEANLSMAQLREAAVAAETASENLETV----LASINDVFMTFDDWYYTYVNRRTLETSGCWEDFMGK-----TLWDV-----FPDL---
VDTQQRAVT---EQTPVQFEFYYPKWQ----VSIF--TTEITDRKQAEAALRESEVRFRQLYI-AYE--RIWGRDRESI---YQDP--QQWIETIHPQNG
--YF--------------------EQEYVRPDGSICWVS-------------------DRGFVIDD------------DNGEPYRVAGV-----------
------------------------------AQDITERKQVEQIKDEFLAVLSHELRSPLNPILGWVKLLQSRKFDEQATAKALATIERNAKLQTQLIEDL
LDVSRILRGKMVLNVTSVNLVSVIDAALETVRVAAA-----AKDIRIQKEFSSEIL-VAGDSSRLQQIVWNLLSNAVKFTPTGGCIEVQLQQVGTHAQIQ
VKDTGKGIHPDFLPYVFEYFRQEDGTTTRKFGGLGLGLAIVRQITELHGGSVKAESLEGQGATFTVQLPL---------------
>tr|K9TAS1|K9TAS1_9CYAN PAS domain S-box OX=118163 OS=Pleurocapsa sp. PCC 7327. GN=Ple7327_4530 PE=4 SV=1
--KVLLVEDNPGLQEFLR-DVSSTQFELTPVESLGEAFSSLARQSFDVVLLDLSLPDSQGLETFVKIRAFPILPIIVLTGLDDETIAIRAMQEGAQDYLV
KGQVDGNLLGRAIRY-----AIERKQAQEELRQRERQLSAV------------------------------FNSALNAIVIADDEGRYAWQSFREQGQIA
GEFRLRR--RDANFLPHRHLSIL--------------RDITESKTA-ALALKQQ-T--ETNIPVMLSFYDANIKSMRNRAGEILETS----WANVRLPNG
F----NVGIGQDITER-----KRAEQKIYEQAALLEITTNAILVRDRANRIIFWNKGAEQLYGWSAQEAIGKNATDLLYKEATSQIDLALQTVIEKGAWQ
GEAGKEVIVESR-WTLVRDEAGQPKSILTVDTDITEKKSLESQRATLASGIAHDLNNILTPILTTAQLLLLPDLDE-RSLQLLKLLEDSAKRGADLVKQI
LSFARGVE-GKRA---VVQVGHLLWEVVKIAKS-----TFP-KSIEIEADIPHELGTVLADATHLHQVFMNLIVNARDAMPDGGKLTITAKNAGRYLAIA
IADTGVGMSPEVLDRIFEPFFTT-----KEVKGTGLGLSTTLGIIKGYGGFITVRSQVGEGSEFRVYLPQI--------------
>tr|B2IY37|B2IY37_NOSP7 Multi-sensor hybrid histidine kinase OX=63737 OS=Nostoc punctiforme (strain ATCC 29133 / PCC 73102). GN= PE=4 SV=1
--KVLLVEDNPGLQEFLK-EVTTVVVDLIPVEQLSEAINYLAKEIFDVILLDLSLPDSQGLETFVIAHQAKATPIIVLTGINDETLAIRAMQEGAQDYLV
KGQVTGDLLVRSMRY-----AIERQRADDALRHSEERFRVA------------------------------LKNSPIFVYNQDMELRYTWVYNPPSGLTV
EEI-LGK--QDLDIMPGEDAQRL--------------TTIKRGVTI-GIGMREE-V--SITIKDTTRYYDLTVEPLRNESQAILGVT----CASI-----
-----------DISER-----KLAEEKIREQAALLDVTTDAICVRDLNNQIIFWNKGAETLYGWKATEAWGKNATELLFDEPSPEIEAALLQATSKGKWQ
GEMGKEILVASR-WTLVCSEQGKPKAILTVDTDITDKKHLEAQRATLASGIAHDLNNILTPILAGAQLLLFPDADE-RTHHLLEILEINARRGADLVKQV
LSFARGVE-GKRI---TLQLRHLIVEVAKILKE-----TFP-RSIQISTDVLQDLWMVSGDSTQLHQVLMNLCVNARDAMPNGGSLIISAENEGPYIAIT
VSDTGVGISKEILDRIFEPFFTT-----KDVKGTGLGLSTVLGIIKSHGGFVNVYSELGSGTSFKVYLPAV--------------
>tr|K9WU96|K9WU96_9NOST PAS/PAC sensor hybrid histidine kinase OX=56107 OS=Cylindrospermum stagnale PCC 7417. GN=Cylst_1043 PE=4 SV=1
--KVLLVEDNPGLQELLR-DVTTSVVELMPVERLSEAFICLAKESFDVILLDLSLPDSQGWETFVRTRQAKATPIIVLTGIDDETLAIRAMQEGGQDYLV
KGQVTGDLLVRSMRY-----AIERQRGEEALRQSEERFRVA------------------------------LKNSPIFVYNQDRELRYTWVYNPFSGLTS
QQM-LGK--KDFDLIPVTDAQRL--------------TAIKSDVST-GIGIREE-V--SITNAQGIRYYDLTIEPLRNESQEVVGIT----CASI-----
-----------DISER-----KLAEEKIREQAALLDIATDAICVRDLDNKILFWNKGAENLYGWMAEEAWGKNATELFYDEPAAEMEAALLSVISKGKWQ
GEANKQVLVASR-WSLVCDEQGHPKSILSVDTDITEKKQLEAQRTTLASGIAHDLNNILTPILAGAQLLLFPDADE-RTRHLLEILEVNARRGSDLVKQV
LSFARGVS-GKRI---TLQLRHLIVEVSKILKE-----TFP-KSIEISTEVPQELWTVSGDSTQLHQVLMNLCVNARDAMPHGGILSISGKNTGPYIVIT
VSDTGVGIPGEILDRIFEPFFTT-----KEVQGTGLGLSTILGIIKSHGGFVNVYSEVGRGTQFKVYLPAV--------------
>tr|Q3M4Z5|Q3M4Z5_ANAVT PAS/PAC sensor hybrid histidine kinase OX=240292 OS=Anabaena variabilis (strain ATCC 29413 / PCC 7937). GN= PE=4 SV=1
--KVLLVEDNPGIQELIK-EVNTAHLELHPVERLSEALKILASDTFDVMLLDLSLPDSQGIDTFVRARETNLLPIIVLTGIDDENLALTAMQKGAQDYLV
KGQVTGDLLVRSIRY-----AIERQRVEEALRHSEERFRVA------------------------------LKNSPIFVFNQDRDLRYTWIYNPIAGWTV
EEM-LGK--QDSEIMSEQDAQCL--------------TAIKYHVTT-GIGTRQV-V--SIGTLLGTKYYDLTVEPLRNESQDIVGIT----CACI-----
-----------DISER-----KLAEAKIREQAALLDITTDGICVRDLENKILFWNKGAENLYGWQAHEVISKNASDLLFREPSLEVETALLNVISQGNWQ
GETGKEIVVASR-WSLVYDEQGKPKSILSVDTDITQKKHLEAQRTTLASGIAHDLNNILTPILAGAQLLLFPDADE-RTQHLLEILEINAKRGADLVKQV
LSFARGVE-GKRI---TLQLKHLIVEVVKILKE-----TFP-KSIEVYTDIPNDLWMVSGDSTQLHQVLMNLCVNARDAMPNGGTLTISAENQGHYIMVT
VSDTGVGISPENLDRIFEPFFTT-----KAVQGTGLGLSTVLGIVKSHGGFVNVYSEEGRGTTFKVYLPSV--------------
>tr|G6FZN0|G6FZN0_9CYAN PAS/PAC sensor hybrid histidine kinase OX=741277 OS=Fischerella sp. JSC-11. GN=FJSC11DRAFT_4329 PE=4 SV=1
--KVLLVEDNPGLQEFLW-DVTTAQFELMPVERLDRTLKLLNQESFDVILLDLSLPDSQGLETFITLRQAPAIPIIVLTGLDDENLALRAMQEGAQDYLV
KGQVSGDLLVRCMRY-----AIERQRIEEALRQSEERFRVA------------------------------LKNSPIVVFNQDKELRYTWVYNTSPGFIN
EEI-LGK--RDLDLTAAADAQLV--------------FDIKQRVST-GIGIRKE-V--SITTAQGIRYFDLTVEPLRNEAQEVIGVT----CASI-----
-----------DISDR-----KLAEEKIREQAALLDVTTDAIFVRDLDNRVILWNKGAENLYGWLVQEAYGKKVVELLYDEPPEEVEIALLTVINQGKWQ
GESGKKVLVSSR-WSLVCQEDGTPKSILTVDTDITEKKQLETQRATLASGIAHDLNNILTPILAVSQLLLFPNIYS-EHEHLLEILEDSARRGADLVKQV
LSFARGVE-GKRM---TLQVKHLIREVVKIIKQ-----TFP-RSIEVCIDVAPDLWTVYGDSTQLHQVLMNLCVNARDAMPDGGSLTISAENVGPYTVVT
VADTGVGIPREIVERIFEPFFTT-----KELKGTGLGLSTVIGIVKSHGGFVNVYSEVGRGTQFKVYLPAA--------------
>tr|B3EF08|B3EF08_CHLL2 Multi-sensor signal transduction histidine kinase OX=290315 OS=Chlorobium limicola (strain DSM 245 / NBRC 103803). GN= PE=4 SV=1
--TLLVVDDNAVSLTLTTHIIKKLGYNALTADNGNTCIELLNTCRIDLILLDIHMPGKNGLEVLAYIRDHFLLPVIMISGSSDIEQAVFSLKMGAYEYLL
KPVDADRLQITVKNALSEFELRRKRLFSAA---ITQS---------PFA---------VVITNE----KG----IIEYT---NPGFTALSGYS-ESEVNG
R--NIDLL--KSGKQ--SPA---------FYRHFWQTI-SSGKIWQGEIINR---------KKGELYTEFCMVSPI-----------------------T
DHSLRIFISIQDISQR-KKDQEALAESEQRFQELADLLPQPVFEIDLNGTLTYTNTPGLDMFYRKEELDKDFNYLILFSPEERLRLQTNIQSIFRGLNHE
YNKDGTDIPILIYSAPI-IRNGKTVGIRGIVLDITERKRSEQQMGQLAAGLAHELNNPINELLQEYRNIRRIAEKGSPPEKL-QELREKEERIGTIIGSM
RNFSFRHAIDQRV---PFDINKGINDTLIIARNEYR------YYADVETSLE-ILPPIPCNPEQINQVFLNLIINSAQKRAEKGKISIHTSHDSNAVFCS
IADDGPGIPDETRRRIFEPFFTT-KE---PGKGTGLGLSISYDIIHKHNGTLVVSSPPEGGTMFTMTLPLM--------------
>tr|A1BHH3|A1BHH3_CHLPD Multi-sensor signal transduction histidine kinase OX=290317 OS=Chlorobium phaeobacteroides (strain DSM 266). GN= PE=4 SV=1
--TVLIVDDSALIRASTSHIIRELGFNPVTAECGDDCIELLNTSKIDLVLLDINMPGKNGMEVLSDIRNHFMVPVIMISGSNDIEQAVQSVKMGAYQYLI
KPVNPDKLEVTVKNALSESKLRQKKLFSAV---ITRS---------PIT---------IAITDN----HG----DLEYV---NPAFSRTTGYS-YKEAIG
K--NPRIL--KSGDQ--PDE---------YYKALWDTI-TAGKVWHGEFHNR---------KKGEMYWEEAIISPI-----------------------T
DHTGKIYISLQDISQR-KKEQEALAESESRFQELADLLPQPVFELDMKGNIIYTNSLGFQAFYTKDDLEKGVSSLALFVPEDRETVLQNIENRLKNINHE
YTKDGTTFPILIYTARI-NRGGVPVGIRGIVLDITDRKQAEQQMGQLAAGIAHELNNPINTLLKEYRLVTEKLEDRPSSEEL-KKLRLAEERITTIIGSM
RNFSFRHAIDERV---QFNINKGICDTLIIARNEYR------YLADVTTKLE-DLPSVPCNPEQVNQVFLNLVVNSAQHRLEKGKITIRTWYDSSNVFCS
VTDDGPGIPPEVRRRIFEPFFTT-KQ---PGKGTGLGLSISYDIVHKHGGTLDVHCPPEGGTVITLSLPLR--------------
>tr|B4SAR3|B4SAR3_PELPB Multi-sensor signal transduction histidine kinase OX=324925 OS=Pelodictyon phaeoclathratiforme (strain DSM 5477 / BU-1). GN= PE=4 SV=1
--TLLVVESSPLLSTSTARFIRQQGYDAVTADNGESCMEFLKSLKIDVLFLDIDIPGKNGREILAYVHDHPDLPVIMTTLVKSESDETDSFTAGAFDYLL
KPINRIRLDMTIKKAITESQRRQESLFSVV---ITNS---------PIA---------IAITDR----EG----NFEYV---NNAFCRTTGYS-MADVIG
K--KPSIL--KSGEQ--SDS---------FYKELWDTI-TSGRNWQGEFHNK---------KKGELYWENSVIVPI-----------------------I
DPTWAIYVSIQDVSLR-KKELEAFSESERRFQELADLLPQTIFEVDLQGWITYTNREGFETFYTQEDFQKGVHSMSLFVPEERGRVMLNMERRMKDIDHE
YTKDGTTFPILVYTAKI-IRNGKPVGVRGIVLDITARKQTEQQMGMLAAGIAHELNNPINEMLKEYRSVIRSFEAGESAVEL-QRMHQMEERITAIIASM
RNFSFSHAIDERV---LFDINHGVRDALTIARNEYR------NCAEIETLLE-ELPLVPCNPEQINQVFLNLIVNSAAKRSVPGKITIHTWCDTTDVYCS
VADDGPGIPQEVQNRIFDPFFTT-KE---PGKGTGLGLSISYDIINKHAGTLSVECPAGKGTVFTLSLPLK--------------
>tr|A1BFV9|A1BFV9_CHLPD Multi-sensor signal transduction histidine kinase OX=290317 OS=Chlorobium phaeobacteroides (strain DSM 266). GN= PE=4 SV=1
--TILVADNCVISRRSISDAICEQGYKAVVAEDGAGCRDLLGKDKTDLLFLDAGIDDDKGVELLVAVKDNPDIPVIVISSSISFEQEALFFKMGASEYLI
KPLSSVRLAVTIKKALLESEYRKKKLFSVV---ITHS---------PIA---------VAITDN----TG----HFEYV---NHAFCKTTGYA-FHEVIG
K--TPRLL--QSGEH--AES---------FYKELWDTI-RSGKNWQGEFHNK---------KKGELYWENSIIIPI-----------------------F
DPSGTLFLSIQDISLR-KKEQEALLQSERRFQELADLLPLPLIETDTEGMITYTNCVGLEAFYTTEDLANGIHGVMLFLPEERQRVILNIEMRLKNINHE
YIKDGTTFPLLVYTASI-MHNNVPVGIRAIVLDITNRKQAEKQMGQLAAGIAHELNNPINSLLNAYRNVIDKVGKDLPKDEV-DRLRQLEERITAIIGSM
RNFSFCHDLQERV---PFYINTGIRDALIITRNEYL------SFADLTTQLE-DLPPVPCNPEQINQVFLNLIINSAQKRSENGKITICTWFDNRSVFCA
VTDDGPGIPCEIQHRIFEPFFTT-KP---PGKGTGLGLSISYDIVHKHGGTLDVHCPPEGGTVITLSLPLG--------------
>tr|I3II91|I3II91_9PLAN Two-component sensor kinase OX=247490 OS=planctomycete KSU-1. GN=KSU1_B0579 PE=4 SV=1
--KILLIEDNPGDVRLIQEMLKEVGFGQFELEHKDSGLSRITRNNIDVILLDLGLPDSQGLPTLTKILSQQKIPIVVLTGLDDEITGIRAIQAGAQDYLV
KGQLGGRLLVSIRYAIERKWMEDDRKLSNA---VKQS---------PSI---------VIITDI----NG----NIEYV---NPKFTQVTGYT-SDEVIG
K--NPRIL--KSDKT--PPE---------EYQRLWDTI-TSGNEWRGEFINR---------KKGELYWDSTCISPI-----------------------K
NPEGTIFVAVEDITER-KRAREALRKSEAKYRILLENLPQKIFYKDKD--LTYISCENLAGDHIRPDEILGKTDYDLY-PRELAEKYRDDDMRVMELNEM
EEKNGQELIIHVVRTPI-KEKGNSMGILGIFWDITEKVAMEREAGEMAAGVAHEINNPITGIINCAQILFNKSEEGSEKDIA-NRIMKEGDRIGKIVHSL
LSFARPGDKKEKK---RYHIHEVLSDTLFLIEAQLR------K-DGIRVTLDIDLPEILAHPQQIQQVFLNLVHNARKYPETHENKILEILGERITIYVK
ITDHGIGISAKIKNEAIKPFFTT-KP---HGEGTGLGLSISHKIIKNHGGKIVIDSIEGEFTKVALILPVE--------------
>tr|K2AKC4|K2AKC4_9BACT PAS sensor protein OX=77133 OS=uncultured bacterium. GN= PE=4 SV=1
--KVLVVDDEKSVRFLLAQMLEGEGYRVSEAADGESAIEIFRKEKPDMILIDAMMPLLDGMSTIIRKLEGQKIPVLMITGLDDDSVVDLAFESGVSDFVT
KP---FQFSVLRQRVKRMLRLKAASIIEEN---IVKE---------RSITEFV--EDGIIITDP----LY----HIISF---NPAAESIFIYK-AHEVMG
K--NISCI--IPDLT--DET---------I------KS-SSAKANESKIIKIRKE---TAGVKGGEKIPVCLTLNG-----------------------L
DSGNKL-ISIRDLTEK-KQTQSTIKMAEMVFENI----KEAICVADSDCVVQFTN-PAFNSLGYTESHIDGSSL-RLIISDPRS--RYDFDNAFKEVQLE
IFKNKAALPVMMLINLI-EAEGLPAHYVVIFHDITEQLKLRKQASTISAGIIHEINQPLNKILSDSLLYLNKKGKSITSKIF-ENLQKISVRIDEIIKQM
RAFTYRQGQAATK---C-DLNAAVEKTHELVKHQLSL-----KAITLHKKLGARVNDVPGNVNIIEEVVLNLVINAIKVHGREKEIICETRLEEDKVIFE
VSDNATGIEDEIKERIFDPFFST-KT---LDGGMGLGLAIVSTILNGYNGRIEVFNNNFGGATFHVELPAA--------------
>tr|K9U8X8|K9U8X8_9CYAN Multi-sensor signal transduction histidine kinase OX=251229 OS=Chroococcidiopsis thermalis PCC 7203. GN=Chro_5533 PE=4 SV=1
--TVLIVDDSPEDRETRRFLLTDDQYIFLETDYGENGLEVCKLVQPDAILLDFHLPDIDGIEFLCELKTQFQLPVIMLTGRGNEDVAVQAMKSGAADYLV
KGKTTSENLRRLQQQLEQSEDIENAAACTNNTAAEQVVETGDLIKLGDGFVARKRSEERLINRQVTEVLGYTTVGLQSLMHPEDLALWRWLCSSDGSVQA
QDVTARKQVEILRRSQERIQRTLETSQIGIGFGSSNGDVL-------EMNDTLL-SILGYTRDFSKLSWRDMSEYAEIDRQAMEQLELTGIEKRLRLQG-
-EVEEHIAFIVDLSDRKRA-EIALRNSEERLRLAFAATQMGSWDWDISTGSITWSDNMEAMFGLTPGEFDGYEFESRLHPEDRDRVLEAIDSTGADYNIE
FRVNGTVRWAQSKGQVFYDRTGKAVRMTGVDLDITDCKHSEVEKDEFVAMVSHDLRSPLNAILGWAKLLRTRQVNAETTARALDAIERNAQSQAKLLEDL
LDVSRMIRGKLELQESQFDLVSLVEESVETTFLAAS-----AKQIHLEFRIPNSRIPISGDRDRLQQVLGNLLSNAIKFTPEGGKIEVQLSQSTNYAQIQ
VIDTGNGISPEFLPHVFDRFRQAQS--PNKQGGLGLGLAIARHIVELHGGTIHAASLVGQGATFTIQLPL---------------
>tr|K9ZMD3|K9ZMD3_ANACY Multi-sensor signal transduction histidine kinase OX=272123 OS=Anabaena cylindrica PCC 7122. GN=Anacy_4122 PE=4 SV=1
--TVLIVDDSSEDRQTHRYLLQDKSYTIIEEESGHAALVLCQQFHPNAILLDFNLPDLDGLEFIAELKQQTMPLIIMLTGYGNEDIAVQAMKYGVQDYLV
KGRTTADLLRQLTQELQRTENVENAVACKCHTKEDQVLEIGSQQKMEDSCVVKKHAEEQLINSQVKELLGYTIVDMGNLIHPDDIESWRWFCCANGSPYA
IDISESKLTEELRQSEAKFRRIVESNVVGIYFGDFHGQIF-------EANDAFL-KMFGYTHELGSIRWDMMTEYQTLDEQKIQELQTLGFEKRVLIEG-
-REKDSACFVLDLTERKQA-EEALRQSEELYRYLSDAIPQLVWIANTEGEYVHVNQQWLEYTGERIEEVRGFGWTRYVHPDDLQITMQALLGTGEPYECE
KRLDGVYRWHLVRGVPIKNELGQVVKWFGTSTDIEDRKQLEVEKDDFVAMVSHDLRSPLNAILGWASILRNRSVDTQTFHRALETIERNAHSQGKLLEDL
LNISRILRGKLHLELRQVNLVSIILAAVETAYPTAN-----ANDIFLESIIDESIEPIMGDENRLLQVLGNLLSNAIKFTSSGGRVKVSLSQYDVYAQIT
VSDTGIGISPEYLPFVFERYYQGDR--AHKQGGLGLGLAIARHLVELHGGTIQATSPVGKGATFTIKLPV---------------
>tr|K9QP32|K9QP32_NOSS7 PAS domain S-box OX=28072 OS=Nostoc sp. (strain ATCC 29411 / PCC 7524). GN= PE=4 SV=1
--TLLIIDDSPEDREVRRYLQQDQCYTIIEQESGEEALALCQQFSPDGILLDFLLPDMDGLEFLAELQKFVMPAVVMLTGYGNEEVAVQAMKSGVHDYLV
KGQTTAERLRHLSKELHRSEK-------------------------------------QLLNGQVASLLGYSQEFLAQFMYPDDFAQWRWFCSADGSPRA
FDITDRKQAEKLRSSNERFRRIVESNIVGIYFGDFSGRIY-------EANDAFL-EMLGYTRALGNLRWDRMSEYQDLDQKKIQELQIGGFEKRVEIEG-
-REEEAVCFVLDITQRQRA-ETALRQSEERYRYLSNAIPQLVWISNVKGECVYVNQRWCEFTGMTTEQISGFGWQTIIHPDDIESVMREWMTTGEPYEQE
LRYDGSYRWHLARAVPIKNEQGQIVEWFGTSTDIDDYKQLEAEKDEFVAMVSHDLRSPLNAILGWAQLLRHRQFDETNFLRALETIERNAHAQGKLLEDL
LDISRILRGNLQLELNQVNLAAIIGVAIETAYPSAN-----TKNIILESVLDQSVPTITGDVNRLLQVLGNLLSNAIKFTPDEGQVTVQLLRKEE-AYIT
VTDTGMGIDPEFLPYVFERYRQAER--HHKQGGLGLGLAIARHIVELHDGTINVTSPEGKGATFTIELPL---------------
>tr|A0ZC02|A0ZC02_NODSP Two-component hybrid sensor and regulator OX=313624 OS=Nodularia spumigena CCY9414. GN=N9414_21781 PE=4 SV=1
--TVLIVDDSPEDRQARRYLLQDQSYTILEEESGEGALTLCRQFQPDAILLDFLLPDLDGLEFMAELKQQSIPAVIMLTGYGNEAVAVQAMKSGVQDYLV
KGQTTGEYLRQLSQELQRSEEVENAAACEFSSSGEQVVKTGALVKMGDGFVAKKQAEAKLTNSQVINLLGYTSEFLSTLMHPEDRARWLWFYSVDGSPRA
FDITERKQAEELRLSNERF---------------------------------------------------------------------------------
-----------------QA-ETALRESEERYRYLSDLIPQLVWTCNSQGECEYVNQRWYELTGQMLEEAKGFGWTKVIHPDDLSSVIPEWTQRKKPYEQE
MRYDGSYCWHLVRNVAIKDEQGRVVKWFGTATDIDHRKQLEAEKDEFVAMVSHDLRSPLNAILGWAKLLRTRQLPPDTVTNALATIERNAQSQEKLLEDL
LNMSRILRGQLQLEVCPVNLVNIVKASVETAYPSAH-----AKGIHLASVIDESIPPIVGDTHRLLQVLGNLLSNAIKFTPSGGRVQVQLAKDDE-ILIQ
VSDTGLGIKPEFLPHVFDRYRQAHC--TAKHSGLGLGLAIARHLVELHGGTIQAHSQEGLGATFSIKLPF---------------
>tr|F2NFZ0|F2NFZ0_DESAR Multi-sensor hybrid histidine kinase OX=880072 OS=Desulfobacca acetoxidans (strain ATCC 700848 / DSM 11109 / ASRB2). GN= PE=4 SV=1
-KRILIAEDEAIVAEDIRRTLEKFGYQVVGMSSGAEVLAKTAEFNPDLVLMDIVLQGKMGIEAAEVIQTRHQTPVIFLTAYADAATLERAKVTEPFGYIL
KPFEDQSLHTAIEIALYKSQAQK-RIAHLNAVLR----AVRNVN------------Q---LIVREQDL-DRLIQQACRLLVETRGYHQAWIFLLERDREM
LELLEQRLR---------P------GCIGFFHQPGLTILSVLPLTRLEIAGPYG--LMGVALP-QAM--LGDVEEQSLFQEVA-----------------
---GDLAFAIIYLTEKNRLAEEERRQTEARLHAIFSYAPNVAIQGFDQGRMLFWNKAAEAIFGRPEINGVADIFDDL-LTDNLKMILAEVDRTGLPYGPQ
HNGHQGIAKATISIPVEQGSK----EFICMSVDITDLKQEEENRVKLAGGIAHDFNNILAALLGYTELSLLGLDLEPDQEQIRKNLEAVIQAGNDLVRQI
LTFSRQSEEKQ----KPVQVSLVVQEALKFLRPSIP------TTIEIQAHLDAKNGMVWADPAQIYQVVMNLCTNAYQAMQEGGILRVSLLQEGSYVKLT
VRDTGQGMDAWVKDRIFEPYFTTKKP----GEGTGLGLSVIHGIVMHLNGAIVVYSEPGRGSTFQIYLPHWK-------------
>tr|A0LLL5|A0LLL5_SYNFM Multi-sensor hybrid histidine kinase OX=335543 OS=Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB). GN= PE=4 SV=1
-AKVMIVEDDAIVASHLERILVQSGYSVVGMATGEDAVERAPVLSPAIVLMDIRLMGDMGIEAADKIRSRLDIPVIYLTAYTDHELLRQARATQPYAYLT
KPVRDRELCAGLEMALYKHETDR-KIRHINQVLR----AIRDVD------------Q---LITRERNR-ERLLEEACQILVRTRGYVMVWIGRTAGTLEQ
VTMGWSPEG---------A------PEKAKAHPPGTCPTLVCALVPMINSDLYG--MLNVNCP-GAF--SD--EELDLLREVA-----------------
---GDLALGMIEEEEERKRAEDALRESEARFRLLAENSTDIISRRLPDGRTLYVSPACRSVMGEPAELQELSAFDFV-HPEDLDRVLREFQAAASSLRPF
RVKDGAYTWLEAGRPIVDQTTA-VVEFHSSSRDVSQRKQEEQERAALAGGIAHDFNNLLMGIQGYTSIMLFEMDRNHPYHDKLKAIESQVRSGAELTRQL
LGFAYSGKYET----KPINANDLLETTATIFKQEIT------ILMDLDADLRAVE----VDRGQIEQVLLNLYVNAWHAMPGGGELRAASVERGEYVEIE
VTDTGIGMDPKTRERVFEPFFTTKEM----GRGTGLGLASAYAIIKNHGGFMEVHSEPGIGTTFKIFLPASS-------------
>tr|D8EW26|D8EW26_9DELT PAS domain S-box protein OX=88274 OS=delta proteobacterium NaphS2. GN=NPH_1914 PE=4 SV=1
-SRILFVEDNPGDRNLIIRHLDQSGRSFVETGSLAEALQKQNERSFDIVLLDLDLPDGMGLEPLTRFRSTPEIPIIVLTGLDDEETGLEAIRNGAQDYLV
KQVNANLMVRSLLHAVERHNLKG-KVDHYNRVLR----AIRSIN------------Q---LIVREKDP-PRLIRQACEVLIETRGYKGVWAALGAGFEDS
FDLLAKDLTRG-----IWP------TCVDKVLKSNERIFIVRPVSLFKSGDIHG--VLAVSFA-NAF--EIEEEEKSLLHEIS-----------------
---DDISFALLETQKQHRDAEEHIRQQHLFLQLLMDAIPMSVFYKDTLGVFIGCNETFANLLGRPKAEIIGKRPHDL-FPEELADKYHKTDMDLLKMGLQ
RITDGNRHDVLIKASYFDVEGN-VAGIIGAMLDITDRK-------AMAGGIAHDFNNVLVAIIGFTELSLHAVEKGSEIESDLQAVYTAAHRAKELVKQI
LTFARLSDEAI----RPIQPTVIVKEDLKFIRSSIP------TTIDIEQDLRSDS-FIMGNATQIHQVMMNLCTNAAQSMEEGGRLRVVLLKPGEYITIT
VSDTGTGIPQDIIGSIFEPYFTTKGP----GEGTGMGLAMVHGIVRAYGGRIFVDSTPEIGTTFSLYLPISK-------------
>tr|Q12AQ5|Q12AQ5_POLSJ PAS/PAC sensor hybrid histidine kinase OX=296591 OS=Polaromonas sp. (strain JS666 / ATCC BAA-500). GN= PE=4 SV=1
--KILIVEDSPTQAQQLQHILEQEGYEVGIARNGRLALKMLPQFRPALIISDVIMPEMDGYELSRRIKTLRNIPVILVTTMSDPQDVIRGLECGADNFVL
KPYDERYMLARVRYVLHREQTYDAAIQRNKDLTQTQSAEVAAIETIPDMFVKDAADRFVRFNRAGEELLGYSDELVGK-----------NDYDLFPEAEA
DAFTSQVTRGMVLDIPEEP--IHTRN-KG-------DRI----LHTKKIPIFDS-KGRPL---YLLGISRDVTKKLEALRKRNEELSKSQE---DLQWSN
SELNKLEARVNQRTQQLTAVVEALRESEARTRLTIDTALDAVVAMDAHGLVREWNAQAETIFGWKRDEAIGKPLAGLVIP-RQHGLERFLATNEGPILSQ
LTAHREGREFPVELPMLQGEW----TFSAFLRDITDRKQMEERKSTFLATMSHEIRTPMNGMFGMLELLGLTELDT-DQRATLAIVRESSQSLLCIIDDI
LDFSKIEAGKLTVRPEVASIKDVIEHVRNMYAGNAS-----GRGLLLKHGTPQISPALMFDPLRLGQILNNLVSNALKFTSR-GSIEIKARTGEDQVRFV
VTDTGMGVSAEDQQRLFQPFTQGGGDTARWAGGTGLGLTICRRLAGMMNGTVEMVSELGKGTTMILTLSL---------------
>tr|F3Z080|F3Z080_DESAF Multi-sensor hybrid histidine kinase OX=690850 OS=Desulfovibrio africanus str. Walvis Bay. GN=Desaf_1445 PE=4 SV=1
--YILIVEDSPTQALRLEQLLLGSGLSVRVAASAVEALALADENPPAVVVSDILMPGMDGYELCRRIRALAHIPVILLTTLADPEDILKGLKSGATNFVT
KPYDPDLLLGRVRQLMRRAKTYENAVIQSRALDRANEA----IASLPAQMVLDAQG---RITATNEAW-----EHMGR-----------NS-PLIPGVLG
RTFGHRGSEDIALDSVAAA--VHEVA-AG-------TRK----NFSSELCV-QS-DGQQR---WLLLYASPMS-------------------------GG
AVVTHMSKRAEQ----------ALRRSEANLAKAQHLAMLGSFEWLSKGDAFIWSDELYRILGYQPGSV--QPGRDFLLR-HLHAFVKCLLDTARRGTPF
LRFRQDGVE-RIGLEAFDATG----KLSRILGTVQDRQKLLERKSEFLANMSHEIRTPLNGILGMTELTLRTGLTR-EQREYLSMVKASADALATLVGDI
LDFSRIEAGKLELERKDFRLREILQAALKPMEMQAE-----AKGLHLTLRIPAVPEHLHGDAGRLRQVLLNLVSNAIKFTPS-GGIDIDVTSGQEELLFS
VADTGIGIDTQLQERVFDIFTQGDSSLSRQYEGTGLGLAISRQLVELMGGAIWVESAIGQGATFNFTVAL---------------
>tr|D8PHL1|D8PHL1_9BACT Putative Hybrid sensor histidine kinase OX=330214 OS=Candidatus Nitrospira defluvii. GN=NIDE3052 PE=4 SV=1
--HVLLIEDNEDDAELIQQALCERSTEAVTINWADRLQTGIQECPVDAVLVDLSLPDSQGLETLDRVRAHHDAPVIVLTGLDNDVVAEKSLLHGAQDYLV
KGRLTGDALRRAMGRHR----VEQALRKLATRDGIWDWEIT-S---GVTWFNEAHQSVYGPAPEN--L---RRGWAEQIHDQAAVLANLA------QV--
-------LQ---SDQNWTAEYRFRRDGTYAYVIDHVLRDHEDHP--------------------------------YRMIGAKADITE------------
---RRQAETMH-------AVQ-----------LAVG------LALE---ESASLSEAIPKILRWLVHSQDKTLHCNALWHQPAENFARTLRQGAWKGDAT
LEADGPILQAAQDAHLIAFPIHTEKEILGIMEFLTCERDLERQLRRMAGGIAHDFNNLLTIINSWAELLTGEGQTTRT-QRGMAQIREAGNKATALTRQL
LAFTRHQIVERQ----PLNLNDRVTDIVELMKRVIG------EDIQLALTLDPALGRVKADPGQIEQVVMNLVVNARDAMPHGGRLDVETLTPGPYVTLA
VRDTGCGMDADTVAHVFEPFFTT----KELGKGTGLGLSTVYGIVRQSGGTVGIESEPGHGTTFTIYLPC---------------
>tr|K9EV92|K9EV92_9CYAN PAS domain S-box OX=102129 OS=Leptolyngbya sp. PCC 7375. GN=Lepto7375DRAFT_2626 PE=4 SV=1
--QVLVVEDVEDDLLLTLRTLRRYTLDYVRVETPEEMQSALDHQNWHIVIADYTLPRFSALEALKLLQAQQDLPFIIVSGTIGEETAVAAMKAGAHDYIL
KGNLARPAVERAEERQKRQRESEAALRQETSPVGIFRTDAQ-G---NYVYVNRQWCDMTGITLEQSRQ---MENHANALHDRDHVLATWQ------AA--
-------LK---DGIPFRLEFRFQRDGTIIWVFGQPERKQGEGI--------------------------------RGYVGTITDISD------------
---RKFAQHVR-------EQA-----------ALLD------VTTDAIGQISFWNKGAETLYGWSAEAALGQDANQLLYADEDEIYQSLIREGSWKERKQ
VTQAGQSITVMSRWTLVTDEQGQPNAILTVNTDITQAKQLESRFLTLASGIAHDLNNILTPIYGVADLLMQLDVDEHI-QHEFEILKNSAKRGSEIINQM
LLFAKGVEGDRS----LLSIRYLIKEIRSFVHKTFP------KSIEIAVDVPKDIDSVKGDETQLHQVFMNLFVNARDAMPNGGKLTVSAVEAGPYIVVI
VTDTGTGIPPDKLAYIFDPFFST----KQAQGGTGLGLSTVHGIIQSHGGFITVDTEVGRGTQFKVYLPA---------------
>tr|B1ZWU4|B1ZWU4_OPITP Multi-sensor hybrid histidine kinase OX=452637 OS=Opitutus terrae (strain DSM 11246 / PB90-1). GN= PE=4 SV=1
--RVLHLEDSTPDAELVAARLTQPECQIQRAASRQQFESALDTGDFDLILSDYTLHGYDGLSALDLARTHPEKPFIFLSGTIGEERAIEALKRGATDYVI
KDRPSRPAMRQSQEEQRLR-RTEEALRQENVADLIVMLDSS-A---HCLYANPAYATAVGRPHDC--T---GRDVFADVHDRAAVEKLFR------AT--
-------LH---QGRNGRAEYRLAHDGTVRYVEAQAVRDFSGTI--------------------------------TQVLIVARDVTE------------
---QRAAREIR-------QQA-----------ALLD------HAQDAIDRVTYWNRSAARIYGWADEEPRQRRAADLWMEEPEIARNATLFYGEWMEMRQ
RSREEVDLIMQSRWSLLQRPDGSAAGFLVINTDIAEKKRLEAQFLLLAGGVAHDINNVLLPIMASTELLM--ATSPET-KQFLASIRSSAQHGAALVRQL
LAFARGAVGQHT----DVMLRPLLEDFVGFVNQTFP------RSISVSLAPGEAPWAVRGDATQLKQVLMNLCINARDAMPEGGRITLHVIKPGPHVVIE
VADTGSGMSPAVLERIFDPFFTT----KEVGKGTGLGLAAVRGIVKGHNGTIAVESWPGRGTNFKIYLPA---------------
>tr|A0ZEQ2|A0ZEQ2_NODSP Two-component hybrid sensor and regulator OX=313624 OS=Nodularia spumigena CCY9414. GN=N9414_23668 PE=4 SV=1
--KVLLVEDNPGDVFLLQELLQEVTTAKVELQPAEQLCEALERDSFDVILLDLSLPDSQGLDTFISTARQKATPIIVLTGLNDETLALRAMQSGAQDYLV
KGQVTGDLLVRAIERQR----SENALRQKNSPIFVFNQDIN-L---SYTWV---YNPMSGWTSQD--M---LGKHDCDLIDAQGLTAIKH------SV--
-------LT---NGIGIREEVSITTLGTRYYDLTVPLRNESQEI--------------------------------VGITCAGIDISE------------
---RKLSEAIR-------EQA-----------ALLD------ITTDAINQIQFWNKGAETLYGWQVQEAVGRNFGDILDNEANEALLSVMTKGKWEELTQ
ITKTGKEILVASRWSLVRDAQGRPKSILIVDTDITEKKRLESQLFTLASGIAHDLNNILTPILAGAQLLLKFDADERT-KRLLEILEINAKRGADLVKQV
LSFARGVEGKRI----TLQIRHLIVEIAKILKETFP------KSIEIHTNIPNELWLVSGDSTQLHQVVMNLCVNARDAMPHRGILSISAAEAGLYVVIT
VTDTGVGIPQETLDRIFEPFFTT----KPVGQGTGLGLSTVIGIVKSHGGFINVYSEVGNGTSFKVYLPA---------------
>tr|Q01RQ0|Q01RQ0_SOLUE PAS/PAC sensor hybrid histidine kinase OX=234267 OS=Solibacter usitatus (strain Ellin6076). GN= PE=4 SV=1
----MSINEERRIVEAVPEGIWVVGGEGRTIFSNRRMAEILGESMSEQTCFGCVFPDELADAERHFARTFGDSRPFLRRGDGSPVWVSISCMPVHDD---
KGTQVG--LLGITERKQ----AEAALREDTAPVMIWVSDEN-K---QLTFFNKTWLKFTGRTEQE--L---GEGWAAGVHDIQNCYETFC------SA--
-------FD---AHRNFQIELRLRRDGEYRSMLCSPRFAPGGVF--------------------------------AGYIGCDIDITDLQSE--------
ERFRELAENIN-------QVF-----------WMLD------LDTS---RVLYISPSFEKVWGWLVETVHAEDRGRFILFREAEAVEEIVRPDGWIDRAF
LDSEGKPYRVA-----------------GIAEDVTAHRELEEELRRLAGGVAHDFNNLLTVIGGYARMLFDGNAQDPT-RAKLEQILTASDRASVLTMQL
LAISRRHAIQPK----LVNVNNLLTSMASLLRRIIG------EHITIETALDPELSCIKVDPHQIEQVVMNLAANARDAMPNAGKFRIETRSAAKCVRLR
IGDTGCGMDDRTRQRAFEPFFTT----KGVGRGTGLGLSMVYGFVHQNQGTIHVSSEPGQGTIFDLCFPA---------------
>tr|D4KJY8|D4KJY8_9FIRM Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain OX=657315 OS=Roseburia intestinalis M50/1. GN=ROI_39180 PE=4 SV=1
MKHILIVEDDNLLNKTLTYNLELDGYTITSVLNARTAAESLKTNIFDLVLLDINLPDGNGYDLCRLIKPEPDTVVIFLTANDQESNQIRGYEAGAVDYIT
KPFSISALQRKIKAMFAMLEHHKPAK--DIYED-------GSLFLDFSEQFASLNGKPLALSAMEYKMLNLFLKNPKQVLTRQQFLEKLWDVDEYVDEHT
LTTSISRIRSKIEAD--GDTYIKTVYGMGVSMDRRRKEMNLNNLSAKKICRVFSMLVITGIFGLCAFFWIWLLV-----------L--------------
-----------IFGKRLSHFTSN-------LCRTLDNMIDG------NEELQKSNDS-ETLFA----RIN-HRLIR------LYE---------------
---------------IM-QKNR---------HKVDMER---QELQMLISDISHQVKTPVSNLQMVTDTLLTKPVSEEERMDFLQGIRSQTDKLDFLFQAL
VKTSRLETGAIRLEKKDSSLFHTLAQAMSSIVYAAE-----KKEIAVSVDCPENL-IISHDSKWTSEALFNLLDNAVKYTPSGGKISVSVVQWEMYVEVK
VTDTGKGISESNQAAIFRRFYREEEV--HDQQGVGIGLYLAREIVTRQGGYIKVVSELRQGSEFSIMLPV---------------
>tr|B4S8R4|B4S8R4_PROA2 Multi-sensor signal transduction histidine kinase OX=290512 OS=Prosthecochloris aestuarii (strain DSM 271 / SK 413). GN= PE=4 SV=1
--TVLIADDSATMRTLISHVVHKLGYDTLTASDGNEAIDRLSNRPCDALLLDLNMPVKSGMDVLDFVRNNYQLPVIIVSGSSDIEQAVECIKLGAYEYLT
KPIDNNRLEITLNNALSEF-SLKQQVRLLNEAQSPVSIVINGLIEYVNPFFCRVTGYSSEVLHQKVSILKS-GEHQGEICNKKKDGELFWENIIISPVRN
EDVTERRFRELS-DLLPQPVFETYFNRAGYTVFGYKGKDLDRGLNVFQLF------------------SPQERGTIENIRKRIKGEKSADYEYRALKKDG
SSFPVLVGIVLDITHRKQYE-RKIKENEANYRNLFQVIPDPIIVADKSGNIVHWNRKALSFFGYSKKELAALS-VEMLFSRTVDDKREMTTMSTASVEAQ
IRTDGFTIEVLV-SSVLFDFSKH-KRLLVVFRDITEQKKSERLKNDFIANVSHELRSPLFSILGFSSTLLKERKELDTTGEFLGIIHDESKRLSSLIEDV
LNVSRIDSGKVAYKKKIIDPAPVVIGACESLKMMAS-----EKSVEFSIHVEPETMQVNADPDALKQVVINLAVNAIKFTPRDGCVRVSLSNDAHWMVLT
VKDSGVGIPESDYDKIFEKFYRVERP-GEEIEGTGLGLPIVKEIIAAHKGSIEVNSKKDFGSTFFVRLPLS--------------
>tr|B8FJD3|B8FJD3_DESAA PAS/PAC sensor hybrid histidine kinase OX=439235 OS=Desulfatibacillum alkenivorans (strain AK-01). GN= PE=4 SV=1
-PKILTIDDEDAIRWSFASFLEDNGYEVVEAANGRLGVELFRREKPDLVLVDLRMPEMDGLEVLSILSKESDVPLIVVSGAGVARDAVNALKMGAWDYIF
KPIESSILLHTVRKNLERAQNLEALVQERSE--KLMEYS-KRLKHITDFFTACST--EDELCTLLSALMENAAAGQGRFFLRGD-DELVLKCSTDAKRRG
WSIPQDALLDKLWDAGEAVIINAYEQGIGYLDA---------ALQGCEGASLLLTP---I---------YTPDKSILGLS-----ILS-KAPDDPFSDTD
LELTALIATHGVEALKDINAARALTASEERFRALTENSSDITLIIGPDNTYTYASPSVFSTYGYKPGMVIGQYTSRNMHPKDV----SMVEKALEKALTN
IKLEG--VRFRHREGVLNSQMG-VGGVVFSGRDVTERKASEQKKSQFLANVSHELRTPLNSII-----LLSGILCENSDLECAQAIQSSGKALLLLINEV
LDLSKIEAGKMAVNTSFFETKTFVQAIEREFLPLAK-----NKGLDFSVRMDADPLRVQSDSQRLEQVLRNFISNALKFT-KQGSVVLRVSRPEKCAAFS
VTDSGIGIPQEKMEEIFEAFTQADGTTSREFGGTGLGLTISREIARLIGGAVRAESEPGAGSTFTLVIPE---------------
>tr|B4VSR8|B4VSR8_9CYAN PAS fold family OX=118168 OS=Coleofasciculus chthonoplastes PCC 7420. GN=MC7420_821 PE=4 SV=1
-GTILTIDDTHLLTEM----LSAQGYKIRIIPNGRLALKSIANNPPDLILLDIIMPDMDGYQVCQQLKKTQNIPVIFLSGLNETFDKVKAFEVGGVDYIT
KPFQVQEVLARVESQLRLQQQVEIALSESEKKYASQDLIWVNYGYSPEEMLGRSFTEEADINLFERLLQGQVFQYETTHLTGEPLLNAIAVVDDQGQVVG
IDITERQAQEALRLSEIRYRELVEFQEQVLVCRWKPDTTLTVNQSQTELIGLLPDFIEDQISDFVKLLVNHCPETSEHIMI----SHQGKLHWFKWK-DQ
PILDEQGQVIEVQSEKLRLSEENLAQAQR-----IAHIGNWVI-----TNQIIWSAELFRIFGLEPNHTEYQQLLDFIHPDDCSEFEETVKQAEQGLCYE
LDFRTTVRHLEVRIEPIFDQHHRVIKLFGTALDITQRQKAETASGQMIAGIAHEINNPVSFIVGNLT-IGRQYFNDPDWHKLLNSIQEGSERIHQIILSL
KNFSRLDEADLK----SVDIHQGIDSTLFILQHRLK-SPGNRQEIQVIKEYGQ-LPPVTCYANQLNQVFMNILVNALESHSSPGVIRISTEVAPPKVIIR
ITDNGIGISEEVQPQIFDPFFTTKPV----GSGTGLGLSISYQIVEKHQGQLSCLSTPGEGTTFMIEIPIK--------------
>tr|B4VM89|B4VM89_9CYAN PAS fold family OX=118168 OS=Coleofasciculus chthonoplastes PCC 7420. GN=MC7420_1866 PE=4 SV=1
-VKILLIDDRKPISDC----LQNTGYEVRIAKSGIKGLKLLEQLTPDLIILDVIMPEMDGFETCRHLKKTKDIPVIFMTAAMDTSNKVKGLSLGAVDYIT
KPIQVDEVLARIKTHLHLRTQAEAALAAQTRRL-----------------IGLALSQETELSAM-------LFRCTQALV--EHKFAQIWTLNSQDNILE
LLYTHTGTHAQVSVGDSIIGYIASQRQPYLSNDIANDPNIS-DPGTVSFAG-YPLIVEAELVGVMVLFSRHFSQTT------------------------
--LDTLASITNEIAQALQESQRWLKAINEAN-PNIIYVHDWVE-----RRNVYTNREIYEILGYTPAEIQGNQVLSLMHPDDLDDHQRRIKYAQIGDVFE
LEYKNGEWRWLFSQETVFKQNTTTRQTLGAAIDISDRKQIELASGRIVGGIAHEINNPANFIYGNIT-YARAYFQDPDWHKLIQSMEIGIVRIEKIVRSL
KSFAKLDEAHLK----PVDIHECIDNTLFILQSRLR-SEGNRPEIKVIKHYGQ-LPPVTCYASLLNQVFFNLFDNAIDYQPVTRSITIKTELSPQSIIIQ
IKDNGIGMSDKVRQHIFEPFFTTKPV----GKGTGLGLAVSHQIVEKHKGEISCSSALGQGSEFIIKIPRI--------------
>tr|G2HBS1|G2HBS1_9DELT Sensory box protein OX=298701 OS=Desulfovibrio sp. A2. GN=DA2_3228 PE=4 SV=1
--SLLIVSEWEEFARGLVARLAACGLEPMLAETPPELSRLITEEPWDMVVAESEAPGMTWQEVLMLVRVREDVPFVLVTPTPDEATAVDAVREGADEVLC
AD--D-WHL---GPAFMRLVRRTLSVHWREINRD--------------------------------ARQWRGM--------VESTVLGIFRCRPWGELMS
ANPAFAAI------------------------FGYPSTDALFDAADPAAPFLDRATLD-RMLNEGEVRDFRARRADGSMFW---IAVNARV----QR-GG
GEISGIEGTVEDIDRR-KAVENMI-IRAKQEEKTFDSVPDVIMIMDAGQRVRRSNMALGRLLGLHPKDMVGRHCNEVLAGVLSDDVCAAIRAMPWGESRT
EELGGHFLVT-L-SPFLTDGQYEGESSVLVAHDISSRKQLEQAQKMLAGGIAHDFNNILGVMMGYTEMLDQTEEGD-A-QRRLSEVLAAGRRARDLIRQI
LTFSRQE----EPSRLPLPPLSPIKETVRLLRATLP------ANVDIRLDLADTG-PLLANLSQLQQVIMNLCGNAAHAMEHGGVLHLSLDAVDGYARLR
VRDTGHGIPADILESIFDPFFT-----TKKPEGTGMGLALVHGIVTAHGGAVAVQSTVGVGTEFEVLLPLA--------------
>tr|Q72A68|Q72A68_DESVH Sensory box histidine kinase/response regulator OX=882 OS=8303). GN= PE=4 SV=1
--SLLAVAPEEDI-HALARTLHHAGIAATLATTPHTLSSALIDEPWDMVLVRPGLPGLSPTDALHLARARSDLQCVALLHREETESAMALLKGGMDDVVV
AD--D-PIL---PAHMTRLARREHSRLWRDMRHD--------------------------------VQQWRGM--------VDNTLLGIFRCQPWGDLVH
ANAAFAHI------------------------LGHDDPAALVQQLRTENSFLDKNRME-HFLSRDCIDDFDLHKVDGTLTR---VMLHARI----IR-DD
GEALSIEGTMEDIERR-KSFEAVI-INAKQEEKTFDSVPDVIIIFSPELRIRRCNKALGRLLGLHPRDLVGRRCEEVLSGSSPNDACALLRSQESAGFST
GELGGDFLVT-L-SPLQTGQNDEPAGIVMVAHDISNRKRLEQAQKMLAGGIAHDFNNILGVMMGYTEMLDQADEDS-P-MRRLSEVLEAGKRARDIIHQI
LTMSRQE----EPSRQMLSLSSPVRETLRLLRATLP------ANVDIRVDIEDTA-PVLANQSQIQQVVMNLCTNAAHAMAKGGVLTVALDAVDTFARLR
VRDTGHGIPSEIRENIFDPFFT-----TKKPEGTGMGLALVHGIVTGHGGHVSFTSTAGFGTEFEILLPVV--------------
>tr|K5YKQ6|K5YKQ6_9PROT Sensor histidine kinase/response regulator OX=1214225 OS=Acidocella sp. MX-AZ02. GN=MXAZACID_10298 PE=4 SV=1
--RVLLLEDSAVDAELVAAHLRKAELEATCVATQADFRAALKRDTHDVVLADYSLPDFDGLSALAIAQLRPHLPFVFVSGVVGEEFATNALKLGALDYVL
KR--NLSRV---APAVRRALRGERRDALAALERS--------------------------------EMNARLA--------AEAAKLGLWEYAPESETLR
WDDTARWI------------------------FGAGPQDELSARCHEEDAALFRAAL---EGQARVQQDIRITLPG------------------------
GALRWVAVHGQALADL-RLVGVVRIAEAQELDRIWRLSDELFAVVDLGGRIRRANPAWESLLGYQEGRLDGCLLSLLLHPEDRDGLAEVLQ-ELRDGRKE
DRFEEGAVYL-A-GRDVTAEREARIAAELAAQ-IEERQRVEQMQRLLTSGVAHDFNNLLTVILGFAERLKTAEDDK-F-LQRLQTMRSAAERGASLTAQL
LAFSRRQ----RLEPKAVDLNETVQGMRELLQSTMG------GSIRIETNLRADLWSALVDPTQIELIILNLAINARDAIEVGGTLTLETANVSDYVMLS
VRDTGTGMSPEVLAKAFEPFFT-----TKEVKGSGLGLAQVYGFAAQSGGGVNIETRIGVGTTISVFLPRT--------------
>tr|J5PML4|J5PML4_9RHOB Two-component hybrid sensor and regulator OX=1187851 OS=Rhodovulum sp. PH10. GN=A33M_2760 PE=4 SV=1
--RILHLEDDPLDAGLVSDYLEAAGLDCTRVQQRGDFAAALEAGDLDIVLADHQLPNFDGVAALALARKAPEVPFVFVSGAFGEELAVEALRHGATDYVV
KQ--RLERL---PAVVRRALRAERLRAEAALRDS--------------------------------EALLRAT--------FDNAGVGMVLMDGDGIVGR
ANATFCGI------------------------VGRQTYRLAGALIHPDD---ERGAL---AALGPVVLEARGLCPN------------------------
GRVIWLRITLSAIGE--QILAVVEVATSEELDNIHQFA----WMADASGWIYWYNERWFDYTGTTLETMQGWGWRAVHHPDHLERVTDKFRASLAAGTEE
DIFIRDATFG-T-NTDVTAQREADEAETLEQRVIAEREAILETQRLLTGGFAHDFNNLLTPIIGLLRRL--GENER-A-QRLIGSAMQGAERAKTLVQRL
LAFARRQ----VLEPRPVDVAALVGEASDFVLRSLG------PDVSLVIEAPDGLPAARVDPTQLELALLNLAVNARDAMPSGGTLTV-ALDRRDYVRIA
VTDTGTGMDAETLAHAIEPFYS-----TKEIKGTGLGLSMVHGLAAQSGGALVLSSRPGAGTRAEIWLPVA--------------
>tr|I4N3G3|I4N3G3_9PSED PAS/PAC sensor hybrid histidine kinase OX=1179778 OS=Pseudomonas sp. M47T1. GN= PE=4 SV=1
--QLLMIEDSPRDAELSLLTLERAGLLITLVFNHQGAEQALRTQVFDLILCDFLLPGSSGAEVLQRARIAPHTPFIFLSGVFGEENAVEMMRLGAIDYVL
KQ--NLTLL---PKAVKRALRRQRVRAEENLEQV--------------------------------EVRARLA--------IDAARMGVWDFSPATGQLL
WDERCRAL------------------------YGVAESTAISDHCHPDDALV-EAKMA-QAMSVGYQAEYRALLPGGGERW---LATSGRA----FF-EG
LVCVRFTGVIQDITEQ-KLATEALRKRTRERDRTWELSRELLAVMRFDMSPIALNPAWEATLGWSRQTLGQMQLWELVHPNDIGATVRETENIASGNVSV
NRMDENLMYA-A-VRDITGERAVVDEEQLREQ-IKERERIEQMQRLLTAGVAHDFNNLLTVILTFLSRIERGVMEK-V-HSRLHNIREAGERGAKLTGQL
LAFSRRQ----RLEPIPVNLNDTVFGMFELLQRTLG------GSIWIQTHTDEGLWSALVDPTQTEMIILNLAINARDAMPAGGTLRLATRNEVAYVVLS
IGDTGSGMNAAVLAKAFEPFFT-----TKDIKGSGLGLAQVFGFAKQSGGGVGIVTAPGQGTTVDVYLPSD--------------
>tr|H0J925|H0J925_9PSED Sensory box histidine kinase/response regulator OX=1112217 OS=Pseudomonas psychrotolerans L19. GN=PPL19_04590 PE=4 SV=1
--KILLVEDSKLDAELILIELERHGFELKIVYERTGLTLALSQQTYDIILSDIILPGFSGAEALRVARLAPETPFIFVSGIFGEVHAVEMMRLGANDYVL
KQ--SMELL---AKAVERALRRERRRAEEALHSL--------------------------------EVRSRLA--------MDASRLGMWEYLPASRTLI
WDERCKAM------------------------FGLPADAVVDRLCGSDGERF-LHTVR-QASADDYRSEYRIRLDNGAQRW---VETRGQP----FF-DA
GVCTRFLGVMLDITQQ-RDAAEKLRERTRERDRTWDLTRDLLLVCKPDGTLVALNPAWEENLGWSRVELLDSSLLALVHPDERFITDNELKQLATGATSV
NRIDAGMTYC-S-GRDISSEVLAMEERQLREQ-IDERERVEQMQRLLTAGVAHDFNNLLTVVLSFLERLTRAASDK-T-QGRVQNIREAGERGAKLTAQL
LAFSRRQ----RLAPKPVKLNETVEGMLELLRSTMG------GSVWIETHLRADCWHALVDPTQIELIILNLAINARDAMAVGGTLRLSTSNQTEYVLLA
VQDSGTGMSEEVLAKAFEPFFT-----TKEVKGSGLGLAQVFGFAKQSGGGVRIETEMGSGTTVLVYLPRT--------------
>tr|F8H7L4|F8H7L4_PSEUT Sensory box histidine kinase/response regulator OX=96563 OS=5965 / LMG 11199 / NCIMB 11358 / Stanier 221). GN= PE=4 SV=1
--SVLFIEDSRHDAELAQLALERSGYTLELVYNHAGVVEALQRRRFDLILADFILPGFSGSQALQEARLAPQTPFIFLSGVFSEEHAVNMMRSGAVDYVL
KQ--NLGFL---PKAVERALRRRRLQAEQALREV--------------------------------EVRARLA--------IDAARLGMWDYEPQSGTLI
WDERCRSM------------------------LGLDTEAPVSQLLHPEDERI-HDEVI-RAISGEFCTCYRVVFGDGSIRW---METRGQA----FF-ES
GQCTRFVGVVMDITEQ-QLTTQSLQERTRERDRTWELSRDLLAVTELDMLPVALNPFWENALGWSYSELMQRPLTQLVHPDDLQATLEENANVGRGKVTV
NRMDGGRIYS-A-ARDITSEIAAVDKRELRAQ-IQERERVEQMQRLLTAGVAHDFNNLLTVILTFLKNLEQAPLER-S-LRRLQYIRESGERGATLTGQL
LAFARRQ----QLAPTAIDLNDTLVSLLSLLKSTLG------GSVSIETDTQADIWHALVDPTQIEMIILNLAINARDAMGDGGRLTLGTRNVVEYVVLS
VTDTGTGMSEEVLSKAFEPFFT-----TKEVKGSGLGLAQVFGFAKQSGGGARIESRVGVGTTVKVFLPRT--------------
>tr|L0GS33|L0GS33_PSEST PAS domain S-box OX=644801 OS=Pseudomonas stutzeri RCH2. GN=Psest_4347 PE=4 SV=1
--SVLFIEDSPHDAELAQLALERSGYTLELVYSHAGVVEALQRRSFDLILADFILPGFSGSQALQEAQLAPQTPFIFLSGVFGEEHAVNMMRSGAVDYVL
KQ--KLGFL---PKAVERALRRRRLQAEQALREV--------------------------------EVRARLA--------IDAARLGMWDYEPQSDTLI
WDERCRAM------------------------LEVDTQTPVDSLCHPDDERI-RDQVA-GAISGEFCTTYRVLFKDGSLRW---METRGQA----FF-EG
GQCTRFVGVVMDITEQ-QLATQTLQQRTRERDRTWELSRDLLAVTDLEMMPVALNPMWELAFDFPLEQLMQHSLTWLVHPDDLQATREENTRVSRGRVAV
NRMDGGRIYS-A-ARDITSEIAAVDKRELRAQ-IQERERVEQMQRLLTAGVAHDFNNLLTVILTFLQNLEQAPAER-S-LRRLQYIRESGERGATLTSQL
LAFARRQ----QLTPTAIDLNDTLVSLLSLLKSTLG------GSVSIETDTQANIWHALVDPTQIEMIILNLAINARDAMGDSGRLTLGTRNVVEYVVLS
VTDTGTGMSEEVLSKAFEPFFT-----TKEVKGSGLGLAQVFGFAKQSGGGARIESRPGAGTTVKVFLPRT--------------
>tr|I0KNR7|I0KNR7_STEMA Sensory box histidine kinase/response regulator OX=1163399 OS=Stenotrophomonas maltophilia D457. GN=SMD_2163 PE=4 SV=1
--RILMLEDSALDAELISAQLQRAGLDFERLWTRNAFIEAIDNRPFDIILADHVLPGFDGDAALALARRIPHTPFIFVSGTLTEELAVQALTRGARDYVV
KQ--RLQRL---PDAIRRARRNQLVQAQAALNES--------------------------------QAQLQQV--------TDAVPALIARLDKDHRYRF
ANKAFAEL------------------------LGRLARDVSGERALPSLRVLQRTSFQ-VELVQSRFVQMDCVPEHA---------------------AD
GSVAGYICMGSDVSVL-KQAELALEARTAELQAIFESSFQHQVLLDLSGRVVDANDASLAAVLADKKDIVGQRFGESLWFANTDGVGAVVDQAVAAAAQ-
---RRSFDVS-L-RPLLDADGVATAVETTARR------QAEQSQKILTGGIAHDFNNILTVISGLLSEA--GEAGA-M-ARALDNALKGVGRAASLTQRL
LAFARRQ----PLRSQAANLNECLLDMQDMLQRALG------ELVQLDIRTAEDIWCVEIDISQLEASVLNLAVNARDAMPHGGRLVIEVDNSHEYVMLR
VRDNGHGMDAATLARVFEPFFT-----TKQVRGTGLGLSMVHGFVKQSGGHVLIDSVEGGGTSITMMFPRS--------------
>tr|B8LBD8|B8LBD8_9GAMM PAS/PAC sensor hybrid histidine kinase OX=391601 OS=Stenotrophomonas sp. SKA14. GN=SSKA14_4042 PE=4 SV=1
--RILMLEDSALDAELITAQLQRAGLDFERVWSRNTFIEAIDHHPFDVILADHVLPGFDGDAALALARRIPHTPFIFVSGTLTEELAVQALTRGARDYVV
KQ--RLQRL---PDAIRRAQRTQLADAQAALNDS--------------------------------QAQLQQV--------TDAVPALIAQLDKEHRYRF
ANKAFAEL------------------------LGRSARDVSGEHALPSLQVLRRSSFQ-VELAESRFVQMDCVPERG---------------------AD
GEVVGYICLGSDVSGL-KQAELALEARTTELQAIFESSFQHQVLLDLAGQVVDANIASLAAVLADKPEVMGLRFGQSPWFAGTDDIGATVDRAIADAAM-
---RRSFDFS-F-RPLLDAEGAVTAVETTARL------QAEQAQKILTGGIAHDFNNILTVISGLLSEA--GEPGA-M-VRALDNALKGVGRAASLTQRL
LAFARRQ----PLHSQAANLNDRLLDMHDMLQRALG------ELVQLDIRVAEDIWCIEIDVSQLEASVLNLAVNARDAMPHGGRLAIEVDNSHEYVMLR
VRDNGHGMDAATLARVFEPFFT-----TKQVRGTGLGLSMVHGFVKQSGGHVLIDSVEGGGTSITMMFPRS--------------
>tr|Q1I875|Q1I875_PSEE4 Putative sensory box histidine kinase/response regulator (Hybrid) OX=384676 OS=Pseudomonas entomophila (strain L48). GN= PE=4 SV=1
--KLLMVEDSSMDAELILMRLERSGLQVRLVFDHVGAEHALRMGTFDLILCDCVLPASSGTEVLAIAQIAPDTPFIFLSGIYGEEHAVEMIRLGATDYVL
KK--NLPLL---PKAVHRALRQRRRRAEEALADM--------------------------------EARARIA--------IDAAGMGSWDYSPQDGRMQ
WDVRCKTL------------------------FGLPADTEMSAGIHPEDPSV-HDAVE-RAMHGHYRVEFRSAPAGAEPRW---LLSSGQT----QF-VD
GQCVRFSGVLQDIHQQ-RQATRALQRRTRERDRAWELSQDLLAVLNKDLTPVALNPAWEASLGFTRERLGQIPLLQLLPEADQQAFLAEIGALSEGRTSV
GRIDDSLLYV-V-ARDISSERESALETRLREQ-IDERERIEQMQRLLTAGVAHDFNNLLTVILTFLKNLDKGLLDK-A-HGRLKHIREAGERGAKLTAQL
LAFSRKQ----RLEPVPLNLNRTLGGLEELLCRTLG------GRVSVRLDLDTHLWFALTDPTQTEMIILNLAINARDAMPDGGQLTLATRNTRDYVMLT
ISDTGCGMSEEVAAKVFEPFFT-----TKDIKGSGLGLAQVFGFAKQSGGGVRIDTAPDRGTQVSVYLPSV--------------
>tr|F6AHN7|F6AHN7_PSEF1 PAS/PAC sensor hybrid histidine kinase OX=743720 OS=Pseudomonas fulva (strain 12-X). GN= PE=4 SV=1
--KLLFIEDSPHDAELALLALERNGLVVTLVYDHEAAERALQRERFDLILSDYLLPGSSGAQALEVARLAPQTPFIFLSGMFGEEHAVEMMRLGAVDYVL
KQ--NLPFL---PKAIDRAMREERRRVEDTLQTV--------------------------------EARARLA--------IGAARMGMWDYVPATDTLI
WDERCRAL------------------------YELEPDADVDGRCHEDDAQL-RQRVN-EALANEFQAEFRLPLSNGSKRW---ISARGQA----FF-DD
GQCTRFLGVLHDITEQ-KQANEALRKRTRERDRNWELSRDLLAVLRFDMRSSALNPAWEQTLGWTRQQLTQGPLWELVHPDDQQDTRAHIERVTSDNVSV
NRMDDDLLYA-T-VRDITHERAVVEEQQLREQ-IAERERVEQMQRLLTAGVAHDFNNLLTVVLTFLIRLEKGNLDK-A-RGRLQNITDAGERGAKLTAQL
LAFSRRQ----RLVPEAVNLGETVQGMLELLKSTLG------GSVLIETATEPDLWHARVDPTQIELIILNLAINARDAMGVGGTLRLSTSNEVDYVVLS
VQDSGSGMSEAVLAKAFEPFFT-----TKEIKGSGLGLAQVFGFAKQSGGGARILTKMGVGTTVKVYLPGR--------------
>tr|B1J6D0|B1J6D0_PSEPW Multi-sensor hybrid histidine kinase OX=390235 OS=Pseudomonas putida (strain W619). GN= PE=4 SV=1
--KLLMVEDSSLDAELTLLSLERSGLQLQLVFDHVAAEHALGEARYDLILCDCVLPGSSGTDVLAIAQLAPDTPFIFLSGIYGEEHAVEMIRLGATDYVL
KK--NLPLL---PKAVRRALRQRRRRAEEALADV--------------------------------EARARIA--------IDAAGMGTWDFRPEEGLLI
WDDRCKTL------------------------FGLPVDTEMSDGIYPEDPRV-REAVE-YAMRGLYRAEFRIAQPNGEPRW---LLSSGQS----QF-VD
GRCTRFSGVLQDIHTQ-RLATQALQRRTRERDRAWELSQDLLAVLNKDLTPVALNPAWEASLGFSRERLSQTSLLQLLPEPDQEALLTELAALAHGRTSV
GRIEDTLLYV-V-ARDITSEREAAMGDRLREQ-ITERERIEQMQRLLTAGVAHDFNNLLTVILTFLERLDKGDLEK-A-RKRLTHIREAGERGAKLTSQL
LAFSRRQ----RLEPVPLNLNRTLGGLEELLRRTLG------GSISVRLDLDHSLWQALTDPTQTEMIILNLAINARDAMPDGGQLTLATRNTREYVMLS
IRDTGCGMSEEVVAKVFEPFFT-----TKDIKGSGLGLAQVFGFAKQSGGGVRIDTAPGHGTQVAVYLPAV--------------
>tr|K6D1G2|K6D1G2_PSEST Sensory box histidine kinase/response regulator OX=1218352 OS=Pseudomonas stutzeri KOS6. GN=B597_00692 PE=4 SV=1
---MLFIEDSPHDAELAQLALERSGYTLELVYDHAGVVEALQRREFDLILADFILPGFSGSQALQEARLAPQIPFIFLSGVFGEEHAVNMMRSGAVDYVL
KQ--NLGFL---PKAVERALRRRRLQAEQALREV--------------------------------EVRARLA--------IDAARLGMWDYEPQSGTLI
WDTRCRKM------------------------MGVAPQAQVNRLCHPQDQRI-REQVA-RAISGEFCTTYRVLLDDGRIRW---IETRGQA----SF-EG
ERCTRFVGVVMDITEQ-ELATQTLQERTRERDRTWELSRDLLAVTHPDMMPIALNPIWEHVFDWSLEQLMEHPLTRMVHPDDLQATLEETARVGRGKVTV
NRMDGGRIYS-A-ARDITSEIAAIDRRELRAQ-IQERERVEQMQRLLTAGVAHDFNNLLTVILTFLQKLEKAPVER-C-LRRLQYIHDSGERGAMLTRQL
LAFARRQ----QLAPTAVDLNEALVNLLSLLKSTLG------GSVSIETDTQADIWHALVDPTQIEMIILNLAINARDAMGDGGRLTLATRNVLEYVVLS
VADTGTGMSEEVLSKAFEPFFT-----TKEVKGSGLGLAQVFGFAKQSGGGARIESREGIGTTVEVFLPRT--------------
>tr|Q4LBM6|Q4LBM6_PSESH Sensory box histidine kinase/response regulator OX=319 OS=Pseudomonas syringae pv. phaseolicola. GN= PE=4 SV=1
--KLLLVEDSIHDVELTLLTLENAGLSIVVVHSHASAEVALKRQTFNVIVCDYLLPSSSGLQVLQVAQHAPDTPFIFLSGVLSGHNSRDTSRHGATDYVL
KH--NLKML---PKVVWRAVREQRILVESELEEV--------------------------------RDRAKLA--------IEAADMGVWELNLTTSQVI
WDDRCKAL------------------------YDWAPGSSLASQTHPDDQLL-SDKIR-QAIS-TFTAEYRIRLANNEYRW---LLFSGRS----VF-RD
GVCIRFSGVLQDISER-KEATQTLTLRTRERDRTWELSRELLAVLRADMAPVAFNPAWQSTLGWSSEIIGKSTLQAMVHPEDLSATLAEIQN-AVGGVSE
NRMEDGLMYA-A-VRDITEERKVMRQQRLIEQ-IEERERVEQMQRLLTAGLAHDFNNLLTIVLTLANLLEKGNYDR-V-SARHRNIQEAGERGAKLTAQL
LSFARRQ----RLDPRSIDLNKTIRGMRDLLHKALG------ATVWYESRLADDLWTVLADPTQTEMIILNLAINARDAMPEGGALVLKTYNEQKYAVFA
LSDSGSGMTPEIRDKVFEPFFT-----TKAVKGSGLGLAQVFGFAKQSGGGVQIESRPGEGTTVAVYFPVA--------------
>tr|E8WUK4|E8WUK4_GEOS8 PAS/PAC sensor hybrid histidine kinase OX=443143 OS=Geobacter sp. (strain M18). GN= PE=4 SV=1
--RILIVDDSPEDAILIVRHLQRE-FSPERVETPDEMEAALDRGGWHLVISDYVMPKFSGLAALKLLHRAIDLPFIMVSGQMGEDAAVEAMRAGAHDYLI
KD--RLSRL---IPAIKRELRRERRMAEEALSAT--------------------------------EARFQSL--------VEQSLVGIFMLQ-QDIFIY
ANPKFGAI------------------------FGYGPEELIEELVTVDDIRV-MTQFL-RPLKPLHFF-FRGRRRDGATID---LEVNGTR----TL-IN
GSGA-VIGTLLDITER-RRAEAELK------WRAVEQSPVSVVITDLRGHMEYVNPKFIEVSGYTEKELIGKKTNILKSGNMNEEFYRDLWGTICSGKEH
GEL-----IS-A-VKNPEGQISHFVG-------ITERKLAIQVQKMLAGGIAHDFNNLLTVINGLLIRLDQSSPMR----KEAEQILRAGERAADLTRQL
LSFSRRQ----IMEPRVLDINRQVKSVQKMLERLIG------EHIRLVTDLHPDAGLIKMDPGQLEQIVMNLTVNARDASDTGGVITVETANCESYVRLS
VTDRGQGMTEEVKQHLFEPFFT-----TKEMRGTGLGLATVYGIVKQCCGYIQVISEPGQGARFNIYLPRT--------------
>tr|C6E6M4|C6E6M4_GEOSM PAS/PAC sensor hybrid histidine kinase OX=443144 OS=Geobacter sp. (strain M21). GN= PE=4 SV=1
--RILIVDDSPEDAALIVRQLQRE-FSVERVETPDEMESALDKGGWHIVISDYVMPKFSGLAALKLLHRGMELPFIMVSGQMGEDAAVEAMRAGAHDYLL
KD--RLSRL---IPAIKRELRRERRMAEEALSAT--------------------------------EARFHSL--------VEQSLVGIFMLQ-DDIFIY
VNPKFGEI------------------------FAYEPQQLIEELVAPEDIKV-MTRFL-RPLMSLHYF-FRGKRRDGSLID---LEVNGTR----TR-VN
GSAA-IIGTLLDITER-KHAEAELK------WRAVEQSPVSVVITDLFGRIEYVNPKFIEVTGYTEEELIGKNPNILKSGMTDAKVYEELWSTITSGREH
GEL-----IS-A-IKNAEGQITHFVG-------VTERKLAIQVQKMLAGGIAHDFNNLLTVINGLLVRLDKGSPTH----KEAEQILRAGERAADLTRQL
LSFSRRQ----IMEPRVLNINKQVRAVQKMLERLIG------EHIGLVTTLSEDAGFVKMDPGQMEQIVMNLIVNARDASETGAVIAMSTDNVDSYVRLS
VADQGQGMTEEVKQHLFEPFFT-----TKEMRGTGLGLATVYGIVKQSGGYIEVVSEPGRGACFNIYLPRV--------------
>tr|Q30YS9|Q30YS9_DESDG PAS/PAC sensor hybrid histidine kinase OX=207559 OS=Desulfovibrio desulfuricans (strain G20). GN= PE=4 SV=1
--SLLFVTCSEELADGIVHSASECGLHPSLVGSAQELSRALAEESWDIILAEPHVAGMPWQQILAAVRVHEGIPFVLVMPAPDPQAAAQAVHDGADEVLL
PA--D-WHT---GAALQRLRSRRQGARRRSRADD--------------------------------EKEWRAL--------VENTMVGMFRCRPWGELVQ
VNPAFAAI------------------------FGYRSPQELLNAHAGKKP----AEIK-ELLPEGLLTEYHAARPDGSGVW---LSVNART----IR-GA
GEISGIEGTVEDIGNR-KSVENMI-VRAKQEEKTFDSVPDIIVLLDSDLHIRRCNMALGTLLGRHPRELVGQDSRKTLDGGTHGPVLDSLPALSRGQSHT
EELGGHFLIT-F-SPLFTGTGSDAEPTVLVARDISSRKQLEQAQKMLAGGIAHDFNNILGVMMGYTEMMDETTEGS-A-MRRLDAVLSAGRRARDLIHQI
LTFSRHE----EPSRHPLNLVSPVKETVKLLRASLP------ANIAIDLRTDTVP-PVNANLSQIQQVVMNLCANAAHAMGPGGNLLLALDSTLTYVRLR
VSDTGHGIDPQILHSIFDPFFT-----TKKPEGTGMGLALVHGIITAHGGTVSVSSVPGQGTDFTILLP-A--------------
>tr|F0EBQ8|F0EBQ8_9PSED Multi-sensor hybrid histidine kinase OX=985010 OS=Pseudomonas sp. TJI-51. GN=G1E_25099 PE=4 SV=1
--KLLMVEDSSMDAELTLMRLERSGLHVHLVFDHTGVEHALKQDHYDLILCDCVLPGSSGTEVLAIAQLAADTPFIFLSGIYGEEHAVEMIRLGATDYVL
KK--NLQLL---PKAVRRAMRQRRRRAEEALVDV--------------------------------EARARIA--------IDAAGMGTWDLRPQDGLLI
CDERCKTL------------------------FGLPASADMTDGIYPDDALV-RDAVE-YAMLGQYRVEFRTAQPSGEPRW---LLSSGQS----QF-VN
GQCVRFSGVLQDINTQ-RLATQALQRRTRERDRAWELSQDLLAVLNKDLTPVALNPAWEASLGFSRERLSQSSLLHLLPDSDQELLLTELAALAHGRTSV
GRIEDTLLYV-V-ARDITSERETALGARLREQ-IDERERIEQMQRLLTAGVAHDFNNLLTVILTFLERLTRGDLDK-A-RSRLKHVREAGERGAKLTSQL
LAFSRRQ----RLEPVPLNLNRTLAGLEELLRRTLG------GNISVRLDLDPSLWQALTDPTQTEMIILNLAINARDAMPDGGQLILATHNTCEYVMLS
IRDTGCGMSEEVVAKVFEPFFT-----TKDIKGSGLGLAQVFGFAKQSGGGVRIDTKPGRGTEVAVYLPAV--------------
>tr|K6TAK6|K6TAK6_9CLOT PAS domain S-box OX=1196322 OS=Clostridium sp. Maddingley MBC34-26. GN=A370_01429 PE=4 SV=1
--NILIIGECDDNANILYRALKNKGYHIINIRNDELVLKYIKENLPDIIILDISINEESGYEISDALGKDSEISIIFINKT-EKINKDRIFNMGGADYLC
TPLNEYEVIARIETQLKLKLMENEIELKDDFSPNNEELTKIN-QVLE-KQVNEKTKQIDDITLKEFNII--LEEEINETKTEEALKE-------------
---SERQFRYSIEEAPV-PIMLYTEDG--QVKKLNRTWTKITGYTISGWAEISEV-----------FTSDIGDKDI-KLFLSDTRLDEGEYTIR------
---------------------------------------------TRYQEVRVWNFYSAYIGEM----QDGHKMRIAIDI------------TEKKHMEE
IQ-------K----NV--EKER---------KLLNELKEYDRIKTEFFSNISHELRTPLNVIFSHELKLKNCEVIDEDIFKYTRIMKQNCYRILRLINNL
IDITKIDSGYFDISKQNIDLVSLVENITLSVVDYVE-----SKGLSLIFDTDIEEKIIACDPEKIERVILNLLSNAIKFTPFGGSIMVNIEDCLEKICIR
IQDTGRGIPEEKIDSIFERFVQVDKSLNRDHEGSGIGLSLVKSLIELHEGTISVKSSIGIGTEFIIYIPYG--------------
>tr|A6LTP7|A6LTP7_CLOB8 Multi-sensor signal transduction histidine kinase OX=290402 OS=acetobutylicum). GN= PE=4 SV=1
--NILIVHEYFEDSRVLIKFLNYRGYNIKSVKKSESIVKSIKENIPDIILINVNLESVNGYQLCEIMRKEEDVPIIFINTCGEAIDRNKIYIVGGNDYLS
TPLEYEEVINRIEMHLRIKFMEHKIKHKGNYDISTQILLKRN-SDLV-NEVIEKDNQLYDITFKEFNII--LEEEMNETRTEEALKE-------------
---SERQLRHSIEEAPV-PIMLYTEDG--FVKKINRSWSDITGYRISEWADISEA-----------FKEELSSTNIKKLFNSEKRQNNGEFSIR------
---------------------------------------------THDGSIRICNFYSAYIGDL----EDGHKMKVAIDV------------TEKKRMEE
LQ-------K----SV--EEER---------KKLYEIKEYDRIRTEFFSNISHELRTPISVIFSHELRLKDCIFENRDKYKYTKIMKQNCYRILRLINNI
IDITKIDSGYFNINEHNIDIIALIENITLSVADYIE-----NKGLSLIFDTNVEEKIMSCDPEKIERIILNILSNAVKFTSSGGKITVSIEDCYDKICIK
IKDTGRGIPQDKLNSIFERFIQVDKSLARDHEGSGIGLSLVKSLVELHGGVISVKSKINYGTEFVIYIPCK--------------
>tr|C6PWD1|C6PWD1_9CLOT PAS domain S-box domain-containing protein OX=536227 OS=Clostridium carboxidivorans P7. GN=CcarbDRAFT_3098, CLCAR_0483 PE=4 SV=1
--SLLIVDDSYYNIKMLSMILRQKWHNVRNALSYELGMKSVMENPPDII---SSAD---GCKVCETLKEHDNIP-IFINNKNEKVDIDDLFNAGADDYIN
MPINYNEVIVRVKTQLKLYFMNKQAWYSEK--SYNQKLMKDN-NDLK-EQVRKNNQQLEEITDKEFNVM--LEEEITETKTEEALRE-------------
---SERQFRYSIEEAPV-PVMIYAEDG--EIMNINKTWEIITGYTASEWGKVSDI-----------FKEDSQCSA-NILYSFEEGRNDGEYSVK------
---------------------------------------------TKSGYVRIWNFYSGYIGRL----SDGRNIRVAMDI------------TEKKHMEE
LQ-------K----SI--EKER---------MRLLEIKEYDRIKTDFFANISHELRTPINVIFSHKLKLKDCNFNDNDKYKYINIMEQNCYRLLRLVNNL
IDITKIDSGYLVINEINCDIVSLIEDITLSVADYIE-----NKGLSVVFDTDIEEKIIACDPEKMERIILNLLSNAVKFTLRGGSIFVNIENGTESICIR
VKDTGKGIPKEKLDSIFERFVQVDKSLTRENEGSGIGLSLVKALVELHEGTISVNSKEGYGSEFIIHIPCK--------------
>tr|G7M0R4|G7M0R4_9CLOT Multi-sensor signal transduction histidine kinase OX=641107 OS=Clostridium sp. DL-VIII. GN=CDLVIII_2737 PE=4 SV=1
--NIVIVNQTHSNINELINILKIHGYNVNMIFGYRLAIENIEKEIPDLILIYIDSHDLSVYELCENIKKNNEVPVIFISEY-EKLDKNKVFASGGSDYLV
IPFNESEVIRRIGIYLRVKFMNNQLEYENKL-IYDEELKKEN-EKLE-RNVLEKEQQLEDITL-EFNVL--LEEEINETKVEEALKE-------------
---NEKQFRYSIEGAPV-PIMLYDEEG--GIKKINKAWTNITGYTISKWINVSDI-----------FKTNLFCTDMADL---KTGEDKGKFFVK------
---------------------------------------------TKEGDIRIWNFYLACIGEF----RNGYKIMIAIDI------------TERTHMDE
LE-------K----SV--KEER---------QKIYELKEYDKIRTEFFSNISHELRTPINVIFSFELSLRNYELESKNKTKYIKIMKQNCYRILRLINNL
IDITKIDSGYFDINKQNVNIVSIVEDITLSVADYIE-----NKGISLIFDTDTEEKVIACDPEKMERVILNLLSNAVKFTSTGGEITVNIEDCFENICIR
VKDTGRGIPKEKLNSIFERFVQVDKSLTRDHEGSGIGLSLVKSLVELHGGTISVESNVKQGTEFTIRIPCE--------------
>tr|D5EKP2|D5EKP2_CORAD PAS/PAC sensor hybrid histidine kinase OX=583355 OS=/ KCTC 12865). GN= PE=4 SV=1
--DVLLFEDNTVDAKLVTREQSRMGCDVVRVASLGDGVKLLRKAAFDVVLIDLSLPDSEGVETVRRASLTSEEVIIVLTGTDDEALALQALKAGAQDYLF
KDQLSSEALSRSIRYSMERANLRVELHN----KETQMEDLNTDA----MLI---LTDECE--------IRFLNPAAAELLDSTSLGEI---FPF------
---EVRG-DE-------KAEEIPTGRGTRFVELR--AVDLVWNGENSML----------------------------VVLH---DITD------------
----------------FRTAEVALSREKHR----LDVTADAVVATDSEGMVERLNAEASRLLGLAVGDVSGVNIREVLLVDPVKRSPVKRVRLFESGRAH
SAFDGEERLVDIRVRTVQDGDGRHGHVIVF-RDVTKLKQHEEELKQLAGGIAHDFNNMLTAVLGNISVVRM-SLGSEEEANRLESAEKAALQARTLTQQL
LSFSKGGAPV----IEATTIDQLVEDCAQFLLR--------GSNVRCEVEKDAELWAVDADKGQVGQVVNNLIINANQAMPDGGVIRLRLEERGDYVCIA
VADEGTGIPAENLNRIFDPYFTT-KK-----DGNGLGLASCYSIIRNHKGVILVESVVGEGTEFKVYLPKV--------------
>tr|K9QFA2|K9QFA2_9NOSO PAS/PAC sensor hybrid histidine kinase OX=317936 OS=Nostoc sp. PCC 7107. GN=Nos7107_2896 PE=4 SV=1
--KVLLVEDNPGDVFLLQEEINTVKVELCPVEQLSEALKLLVYDSFDLMLLDLSLPDSQGIDTFVNARQAKATPIIVLTGLDDETLALRAMQEGAQDYLV
KGKVTGDLLVRSMRYAIERQRIEDALRQ----SEERFVALKNSP----IFV---FNQDKE--------LRYLGKHDSELLPDEQNTTIK--KDV------
---LTTGIGT-------RAEALTTPQGIRYYDL---TVEPLRNESQDIV----------------------------GITCASIDISE------------
----------------NKQAEAKIREQAAL----LDITTDAICVRDLENKILFWNKGAENLYGWQASEAWGKNVSELLFDESCPEFEAAWLNVISKGKWQ
GELTGKEVLVASRWSLVRDSHGKPQSILTVDTDITEKQHLEAQLRTLASGIAHDLNNILTPILAGAQLLPL-KFPDAERTQHLEILEINAKRGADLVKQV
LSFARGVEGQ----RINLQPRHLIVEVAKILKE--------TKSIEVCLDLSPHLWTVSGDSTQLHQVLMNLCVNARDAMPDGGTLTITAEKVGPYTVIS
VCDTGIGIPEEILDRIFEPFFTT-KAV---GQGTGLGLSTVLGIVKSHGGFVSVESQVANGTCFRVYLPAV--------------
>tr|K9QUN7|K9QUN7_NOSS7 PAS domain S-box OX=28072 OS=Nostoc sp. (strain ATCC 29411 / PCC 7524). GN= PE=4 SV=1
--KVLLVEDNPGDVFLIKEEVNTTRVNLENVEQLSEAFHLLANQSFDVMLLDLSLPDSQGLETFVKNRQAKTIPIIVLTGTDDENLALRAMQEGAQDYLV
KGQVTGDLLVRSMRYAIERQRIEDALRH----SEERFVALKNSP----IFV---FNQDRD--------LRYLGKQDCEMISYEQRTAIK--YHV------
---LSTGIGT-------RAEAITTAQGTQYYDL---TIEPLRNESQEIV----------------------------GITGASIDISE------------
----------------RKLAEAKIREQAAL----LDITTDAICVRDLENKILFWNQGAEKLYGWQAYEAIGKNASELLFPEPAPEIEAALLQVISQGNWQ
GELKGKEIVVASRWSLVHDEQGKPKSILSVDTDITQKKHLEAQLRTLASGIAHDLNNILTPILAGAQLLPL-KFPDAERTQHLEILEINAKRGADLVKQV
LSFARGVEGK----RITLQLRHIIVELAKVLRE--------TKSIEVVTDIPKELWTVSGDSTQLHQVLMNLCVNARDAMPNGGTLKIVAEKQGPYIVIT
VSDTGVGIPEEHLDRIFEPFFTT-KAV---GQGTGLGLSTVIGIIQSHGGFVNVDSEVGRGTTFKVYLPAV--------------
>tr|K2EVE8|K2EVE8_9BACT Multi-sensor signal transduction histidine kinase OX=77133 OS=uncultured bacterium. GN= PE=4 SV=1
MSKILIIYNNQDSADLL----KDVGYDVTVAFSQEEAFKAANELSPDIALVDTSCTEINISNICKKLKKTNDIQIILLTSQDSPSEEVL---VGADGYIT
KPFRDNILIATVNAHLRIKKLLDILY--TNNSEL-----------------AKSLYQ-----------LNVLYNTSSQTLDKTKLVSIMN----IGLEKS
LNFSI--CLALIINNPEDATLIVNSLISGRLEQALKLRAIIGYKSLFENAKLPFELSI---------DNVKVEKNIK----------SEE----------
-KTYDLP--------------------VLEFDSLFSPIS-----------------TSDQFFGT----------VEILRESE---FSGEDSTCFQTVVKQ
-------VSLPLESAILYEEIKK---------TNIKLEKLEKLKSEFISIVSHELRTPLTSIKNSLDIMLTGKTGEITQDNFLSIAKRNVDRLSGIINDL
LDLSKIEAGKMEYRFKPLNILEPIQFVISTFESLAE-----KKSIKLSLNIADELPQMYGDINRIEQVLSNLLSNAIKFTPESGEIKISAKKKGDYVKIS
IEDSGIGINEIDIPKVFDKFQQIESSLSREVGGTGLGLPIAKQLIEAHRGEIWLESEPQKGSTFSFVLPV---------------
>tr|I3R5J9|I3R5J9_HALMT PAS domain S-box OX=523841 OS=14739 / NCIMB 2177 / R-4) (Halobacterium mediterranei). GN= PE=4 SV=1
--RVLHVDDEPSLTDLVSIYLEREDLSVSTSNSGADALKRIRQERIDCVVSDYDMPDIDGLEFLRAVRAEHDLPFILFTGKGSEEVARDAFRVGATDYMQ
KDTGTDQYTNRVVNAVSQYRAK--AASE------RYGTAIEV---LDSGVSLDSEGRFTSADGVFCGLTG---------YEREDILQHFA--DLAADS--
-G---DEIRDAFVKVPDKPE-----GFEAVLSSGPAYPHDDELLCEGHLA----------------------LRP-----------------------TE
DDESAVIGTLQDVTERRRR-RNRLRY----ETRVLDTSTSLMSADEIGTKIEWTLQTVSEVADLDRCSVYLYNDEACVHNWPLHCVSDLPPDASNTLLGA
APMKWSFVGVETNRSWTDTE-VDLLRSVANNITHTARQRRERELDEFASVVSHDLRNPLNVAKGFAELAREED--------DVTYLDRALDRMETLLNDV
LSLARQGRKV--GETNSVVIEDVAEQAWKAVDT---------GDAVLVVE--DGLGMTQADQGRFQQAFENLFRNAVEHGTPKLVVRVGPTQ----SGFY
VADNGPGIPADKRETVFEHGHTT------SKSGTGFGLSIVESIVEAHGWDIEVTESDLGGARFEFDIGG---------------
>tr|D4H058|D4H058_HALVD HTR-like protein OX=309800 OS=14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii). GN= PE=4 SV=1
--RVLHVDDEPSLTDLVSIYLEREDLSVSTSNSGADALERLRQERVDCVVSDYDMPDIDGLEFLRAVRSEHDLPFILFTGKGSEEVARDAFRVGATDYMQ
KDTGTDQYTNRVVNAVSQYRAK--AASE------RYGTAIEV---LDSGVSLDSAGRFTSADGVFCELTG---------YDREAIIREFA--DLAAEA--
-A---DEILSAFERVPNAPE-----RFETVLSPGPAYPHDDDLLCEGHLA----------------------LRP-----------------------TE
DDESAVIGTLQDVTERRRR-RNRLRY----ETRVLDTSTSLMSTDEIGTKIEWTLQSVGEVADLDRCSVYLYDDEARMHDWRLHRVSDLPPEASDTVLDA
VPMKWALVGVETSRSWTDTE-VDLLRSVGNNVTHTARQRRERELEEFASVVSHDLRNPLNVAKGFVELAREED--------DVTYLDRALDRMDTILNDV
LTLARQGRKV--GETRSVAIENVAERAWKAVDT---------GDAVLVVE--DGLGTTQADQGRFQQAFENLFRNAVEHGGSELTVRVGPTE----TGFY
VADNGPGIPADERDTVFEHGHTT------SDSGTGFGLSIVESIIEAHGWDIEATEADLGGARFEFDIGG---------------
>tr|D2RPP9|D2RPP9_HALTV Multi-sensor signal transduction histidine kinase OX=543526 OS=VKM B-1734) (Halococcus turkmenicus). GN= PE=4 SV=1
--HVLCVDDDPDIRSVTAATLERSRFVVSTANSGRDGLSRLDGTEIDCIVSDYEMPGMDGLEFLAAVRERDEMPFLLFTGTGSEAIAREAISAGVTDYLQ
KGTGTDQYVNRIENAVEKERAR--RESER--ELERYRTLVET---VDDPMVLDADGRCTIINDAFCDLLG---------VDRDRIVEPIA--EFISGE--
-A--LERGAKTVYHLSDRAD-----RFEFTIGTE------DGTERVGEAN----------------------VTA-----------------------LT
DDDGRFAGSTAVVRDITAR-KRRERE----LAR---------YIVDL---------APIALFVLDADATITWCNDAFTEEIVISKYTDLSSSVDRTKYVQ
SPDERIH-DHTELLPLEDGE-F----GTIHAIRDIRRRRSQRELEEFASVVSHDLRNPLNVARGTLELHAEDCPQS---GESIERVRWSLQRMDDLIDRL
LSLARHGRTI--GEQTPISLSTSVHRAWNAVDT---------ADATLECD--VD-TTIVADEGRLQALLENLFRNAVEHGSTGVTVTVTVGPLEPIRGFY
VADDGSGL-DSSVDELFEFGYTT------AEDGTGFGLAIVEGIAEAHGWAVTARNGDDGGARFEISGVD---------------
>tr|Q5UXE0|Q5UXE0_HALMA HTR-like protein OX=272569 OS=B-1809) (Halobacterium marismortui). GN= PE=4 SV=1
--RVLYVDADCDDITVVTETLSGSPFTVTVCETADDALTSLENASYDCVVSEYRLPDRDGIELLRAVRDQSDLPFLLFTDDGDESVASNAISAGVTDYMT
KTPLSEQTEQRITAAVARYL----EEAD----------ILDR---MTDGFAVDEDWEFTYLNERGRRVIGRAM---ALDGDTADLLQNIW--EAVPSI--
-E--GTEFSKQYRRAKQEPT-----SFEGYFEP---------LQTWFDVS----------------------VYP-----------------------SP
TGISVY---FRDITERHRH-EEEIRS----RERTLREIYGVISDLDFEEKVERLLEIGQNALKAETAALSHIDGDEIVRDRQTLVLADIAADRPELKAYG
TPVDGSVYGTERRDSFSEWE-VTLVELMGNWISYEERERREQELEDFASVVSHDLRNPLNVAVGRLTLVDEEG--D---PEHVESLRRSLERMDELIDDV
LALARGGHKV--IDATETSLDDIITAAWDTVES---------SDATLRVD--TD-ARITGDQTRLQQLFENLFRNSVEHGSTPVTVRVGTLAD--GRGFY
VADDGPGIPEDERDEVFERGYTT------SDDGTGFGLAIVSEIVDAHGGRITVAESEDGGVRFDVTGVQ---------------
>tr|E4NQB3|E4NQB3_HALBP Fused histidine kinase with GAF domain/response regulator receiver OX=469382 OS=10706 / PR3). GN= PE=4 SV=1
--RVLYVDGDSDYADRVRSSLVRESFDVQTAPDAECALEHLRESDVHCIVSEYQLPDTTGLAFYDRVREFSDLPFILFTASGSEEIASDAVSAGVTDYLL
KREGSDQFEDRIGDAVCSYRERRSERQA----------VFDR---MADAFAVNADWHVTVLNEQAKTVLTAA-----MDDDIGEIERHLW--EELPDA--
-V--GTTFYEKYHEANQEPV-----SFEEYYEP---------LDTWFEVR----------------------VYP-----------------------SE
TGLSVY---YRDITERYRQ-REMLES----RERVLREMHDIIAEKSFTEQVEAVLELGREELGTEYGTLSEIRGDEVVATDKTLVLGDISQDSAGRQDSG
APVDDDVYGTTPRDQFSEWE-VTLVDLMSRWVSYEQRRQTNEKLGQFASIVSHDLRNPLNVARGHIELAQNEC--T---NEHLDAVERAHDRMETLIENL
LTLARSEERI--GDTELVNLAELAEQCWETVET---------GTASLDVE--TD-RTLLADEPRLRQLLENLMRNSVEHGSTSVTVRVGDVEG----GFY
VEDDGPGIPPDERASVFDSSHTT------KTEGTGLGLAIVERIAKGHGWSVCVTEGTGGGARFEFTDIE---------------
>tr|G2MNW7|G2MNW7_9ARCH Multi-sensor signal transduction histidine kinase OX=756883 OS=halophilic archaeon DL31. GN=Halar_0299 PE=4 SV=1
--HVLHVDDDADFLELVATYLERESLTVSTANNVEAAHDQLDATDIECIVSDYEMPGTDGLEFLETVRGQYRIPFILYTGKGSEEIASEAISAGVTEYVH
KATGTEQYTNTVENAVAQYRAER-QVHEN---ERRFRALIEN---STDIIILDEHGRITYQSPSAERVFGL---------PDDEVLEPAF--DFVHPD--
-D--RERVMDEFFNAHGDRP-----TVEYRLERAD-----GSWRRIESTG----------------------MNR-----------------------VD
DAIEGFIVNSRDITERETL-RSTVQD----REQKIKALHDVATCDSCSDAYTLTIDAAERILDFEMCVIGIEDDGRAASEDETASVDEIPGDSPYR---S
IPIRGNFQADTEPDAFDQTD-LELAELLVSHTSAAQNLERTKELEEFSSVISHDLRSPLNIAEGMIGLAKESG--D---LSHLSKAETALDRMNELIENL
LTLAKEGEML--DDREPVAVADVAGQAWSTSTT---------GEASLSVA--ESLGVVSADRSRFQTLFENLFRNAVEHSSTAVTVEVGRLS----DGFF
VADDGPGIPNEQRNRMFDDRSLQ------LHEREGFGLVIVQQIVEAHDWQIRVAESDSGGARFDVTGAT---------------
>tr|E4NTL6|E4NTL6_HALBP PAS domain S-box OX=469382 OS=10706 / PR3). GN= PE=4 SV=1
--SVLYVDDEPELSSLVATYLEREDLSVETATNPSDALGLLSQDDFDCIVSDYEMPEMNGLELLRAVRATRNLPFILYTGKGSEEVARDAFRVGATDYMQ
KTTGTDQYANRVVNAVSRNRAE--EATE------RYDSVFEA---LETAVVVDESGQFVSVDDVFVELIG---------YDRETILNHVS--SLSPDD--
-E---QKIRDELDRLKDGVT-----RFETDVCTAS----KERIHCIATMS----------------------FKS-----------------------FE
GGAQRVVGTLHGVTEQRGQ-QERDQY----LARVLDTSTTLMSVDEIGTKIHWTLQSLGEFADVDGAAVYSYDSDQKTHEWRATDASTLSPSEPEP-LLA
LPMNWSLVGSTTSRQWSDKE-VSLFGTAADMLSYTERQQRERQLEEFASVVSHDLRNPMNVVDGFMELARDTG--------DVSHLDRAMDRMDALVNDV
LELARQGRTV--GETSPVDLTGVVRRAWSAVET---------GEATLELD--DDLATVSADASRLTQVFENLVRNAVEHGG-DVTISVGPQT----PGFY
VEDDGPGIPEADRSAVFEQGHTT------SEDGSGFGLSIVEGIVEAHGWTIGVTEGSDGGARFEI-------------------
>tr|Q5V6I9|Q5V6I9_HALMA HTR-like protein OX=272569 OS=B-1809) (Halobacterium marismortui). GN= PE=4 SV=1
--LVLHIDDEPDFLDVASEILAQQSLKIITAASAAEGLDKLATRSVDCIISDYRMPEKDGIELLKAVRAEYDLPFILFTGEGSEAVASDAIAAGATDYLR
KGHGTERYANRIENAVEQYRTNQ-RAAE----LERVRALVSN---IDQALRASS---LSEIKTRVCETIS----------DSEPYRERDPETDRIEPQ--
-A--WAGVEDAYLDTVTADP-----TGQGPAGTAVR---KRRIATSQNIQ----------------------ADPAFEVWREEALDRYSSRSFAFAEDEQ
ALLSELGNSISHAMHSLKI-RDELRA----ERTALDSLADIFYVIDSAGTVQRCNEQFATLAGYADEKISDLDALEEEREGQSTIEAEFRTAAGK-RVH-
-------------DRLTDQD-GDLIGLVGTGRDISERTRRERELEQFAATVSHDLRNPLTVIQGRLALLQAEQ--S---NEHLAVIETATDRMERIVEDL
LWLAREQQEI--GSLEPVSIDTAAEAAWKLVSA---------DEAELYCD--CGADTVKADTDQFRHLLENLFRNTIDHAGRDVTVVVGGIFAD-ATGFY
IEDDGPGIPAEDREKVFEAGYST------SESGTGLGLNIVKRVADAHGWDICATESSMGGTRFEITGLE---------------
>tr|G0HZU9|G0HZU9_HALHT HTR-like protein OX=634497 OS=102182 / NCIMB 2187 / VKM B-1755). GN= PE=4 SV=1
--AVLHVDDEPDFLDVATEILEQQSLNVITAASATEALDCLATTRVDCLISDYRMPGKDGIELLKTVREEYDLPFILFTGEGSEAVASDAIAAGATDYLR
KGHGMERYENRVENAVEQYRTNQ-RAAE----LERVRDLVSS---IDQALRASS---LSEIKTRVCEIIS----------DSEPYLEQEPDTDRIEPQ--
-A--WAGVEDEYLDTVTADP-----TGRGPAGTAVR---ERRIATSQNIQ----------------------DDPAFEVWREEALDRYSSRSFAFSEDEQ
ELLDELGDSISHAMHSLKI-RDELRA----ERTALDSLADIFYVLDSEGNVQRCNEQFERLAGYADEEISEFDALEEEREGHSTIEAEFLTGAGK-RIH-
-------------DRLTDQD-GNLIGLVGTGRNISERTKRERELEQFAATVSHDLRNPLNVIRGRLDLVQETH--S---SDHLAVIETATERMERIVEDL
LWLAREQREI--GSLEPVAIEVAAEAAWKLVSA---------DEAELHCD--CEADTIKADTDQFRHLLENLFRNTIDHAGLDVTVVVGGIFDD-TNGFY
IEDDGPGIPVEDREKVFEAGYST------SESGTGLGLNIVKRVADAHGWDIRVTESSMGGTRFEITGLE---------------
>tr|G0HTH2|G0HTH2_HALHT Adaptive-response sensory-kinase OX=634497 OS=102182 / NCIMB 2187 / VKM B-1755). GN= PE=4 SV=1
--RVLHVDDDPAVVEAATSALEQEHITVETATSVADGIERLDSDAFDCVVAGYDLPEQTGVEFLDAVRKRADLPFVLFTSEGSEAAASDAISAGVTEYLR
VDGGAEPYAHTVVDAVERTADNI-EHAQ----STRRERAIEE---LHRAFRATTEDAVAQVTVDTARTIL----------NMPAN-VHFADGDSLYPV--
-A--WT----EQVEEGTPPE-----AGEALAWQAFE---TGEARVHDDIT----------------------SSPDRYNPETDIRSEGSSEVSAFDDTDV
TLARTLSVHATAALNRLDR-DRQLRE----EREALDTLDDLFYVIGTDGSLRRWNERIPEVTGYSDDEIGDMAVADDEHGARVTLEAEILTADGE-RIY-
-------------TRLTDAD-GAVAGTVGIGRDISQRRAYERQLDEFTSIVSHDLRNPLTVAEGNLELAKTEC--D---SDYLDEVSRSHERMRALIDDL
LTFARAGETA--TDLESVTLANIAEECWQTVEG---------DRATLVVE--ADRQ-IRADTAKLRRLVSNLLRNSVEHGSTNLTVRVGTVEDTDRHGFY
VADDGPGIPSEDREQVFEGGYST------GENGTGFGLKIVQRIAEVHGWTVTATESEAGGARFEVTGLE---------------
>tr|G0HS53|G0HS53_HALHT HTR-like protein OX=634497 OS=102182 / NCIMB 2187 / VKM B-1755). GN= PE=4 SV=1
--TVLCVDDEPSYADLIATHLERNDIDATGVTSATDGLSYLDAHDVDCIVSDYDMPGIDGLEFLEAVRARDDMPFLLFTSQGSESLASEAVTAGVTDYIQ
KVQGSQQYAQRIRNTVERVRAK--ATADT--AQERTKRILDA---TSDAAISVAD-TVVYANPAAVEFFG---------ADSDDLCRPLT--DLVEPT--
-T---DGGTETVERVNGQTG-----QVSRTIRTL------AGNSVQASVT----------------------ACD-----------------------VT
WDGED--GTVSVISDRGDT-DEREQR----LEATRQLMAAEVHVAGIG------VNAAAEIIGLDANAVHLLNDDPVAATAEATAVPDLEEDVQNPPISY
LPLHGILIASTTVDAFDEAD-IANMEAALAAVERDQLRDREQELEQFATVVSHDLRNPLNVAIGRLGALKEEC--D---DDNMAAIEQALERMQALIDDL
LLLARTGDDI--TEMETVALATAVEDCWEVVDT---------GDATLVVD--TD-RKIQADMTRLKQLLENLIRNAVEHSATGVTVTISEIP----GGFA
VSDDGTGIPEADREAVFESGYST------TTDGTGFGLSIISQIAAAHGWTVTLTESDAGGARFEFTGVD---------------
>tr|Q5UZW5|Q5UZW5_HALMA HTR-like protein OX=272569 OS=B-1809) (Halobacterium marismortui). GN= PE=4 SV=1
--TVLCVDDEPSYADLIATHLERNDIDATGVTSATDGLSYLDEHNVDCIISDYDMPGTDGLEFLETVRARDDMPFLLFTSQGSEALASEAVSAGVTDYIQ
KSHGTQQYAKRVRNAVERVRAK--ATADA--TQARTKRILDA---TSDAVVSVAD-TVVYANPAAVDLFS---------ADSDELRRPLT--DLVEPT--
-A---DGGVETVERVDDQTG-----QARRMIRTL------AGNSVQASIT----------------------ACD-----------------------VT
WDGDD--GTVSVISDRSDT-DEREHR----LEATRHLMAAEVHVAGIG------VNAAAEIIGLDANAVHLINDDPVAATAEATAVPDLEEDVQNPPISY
LPLHGLLIASAAVDAFNEAD-IANMEAALAAVERDQLRDREQELEQFATVVSHDLRNPLNVAIGRLGALKEEC--D---DDNIAAIEQALDRMQALIDDL
LLLARTGDSI--TEMETVALGTAVEDCWEVVET---------GDAALVVD--TD-RKVQADMTRLKQLLENLLRNAIEHSAAGVTVTISEIP----GGFA
VSDDGPGIPDADREAVFESGYST------TTDGTGFGLSIVSQIATAHGWTVTLAESASGGTRFEFTGVD---------------
>tr|C7P3W2|C7P3W2_HALMD Multi-sensor signal transduction histidine kinase OX=485914 OS=NCIMB 13541) (Haloarcula mukohataei). GN= PE=4 SV=1
--DVLYVDPDTD--STVRDSF-GDSFRVTHVADAATALAHVTDGSTDCVVSEQDLPDGSGLSLLRSIRRRASLPFVLFTDDGSETVASEAIDADVTGYLR
RTPLEEQLPTTVTEAVSRPH----EQSA----------ILDR---MTDAFALDVEWRFTYLNERAREIVCDAA---DVDRSIDDLVTRIW--DLLPEV--
-V--DTEFYDRYTEAEQRVT-----TFEAEYEP---------LGTWFEVR----------------------AYP-----------------------SV
DGLSVY---FQDVTDRKHR-IETLRE----RERILKEMYRVVSTLSFEEQVDRLLSIGQSVLGTDYGALSSREGDEVVRDPETLVLEDIARDAPELRAYG
TPVEDEVYGREPREPFSDWE-IALVELLGNWVSYEERRRHQNEIEEFASVVSHDLRNPLSVALGRIDVARETG--A---EEHFDAIERSLQRMDTLIEDI
LSVARDGRTV--SEPTPVDIETVAEDAWAVVES---------DEATLRID--VD-DRFLGDATRLQQLLENLFRNAVQH---GVVITVGPLEE--GTGFY
VADDGPGIPEDERDDVFQSAYTT------IDDGTGFGLKIVSEIAEAHGGYVTVTDGDDGGARFEIRDLP---------------
>tr|I3R4B7|I3R4B7_HALMT HTR-like protein OX=523841 OS=14739 / NCIMB 2177 / R-4) (Halobacterium mediterranei). GN= PE=4 SV=1
--TILHVDDDPAFAQLVAINLERRIANVETYERGTAVLDQLATGGVDCIVSDYQMPEMTGVELLETVREQYDVPFVLFTGHGSEEVASDAISAGVTDYVQ
KNTGDDQWLNRVERAVREHRALA-AREE----ADRRSTLIEA---MPGVARSP----LDSFVSEGCLELT----------GYEREADISWGGDVVHPN--
-D--RGGGWDEIVDA----E-----AGE-------------RYKRTYRIQ----------------------TRTGETKWVR---------EHGLGVTED
GEVAAVEGYVYDVTEKHHR-RMELRE----KESLFESVPIHLFVKDEAARHVRVSSALDALVGKTDLELSTLPEFEHHKQAAIIDKEEYLPDLDRLKVW-
----------------TDDD-GNVVGIIGTTLDITERKRQEQEIGEFASIVSHDLKGPLNVAQGNLELVREET--ET-ENERLDTVADALERIGDIVDDV
LSMARGGAND--LERDNVDLEEAVVEAWRSIDE---------TDATLETP--DRLGTIHCDRVRLVRLLENLFWNAVEHGSTGPTITVRRLQD--DVGFA
VIDDGPGIPEESREHVFERGYST------DEDGTGYGLSIVADIAEAHGWNPRVRTANGGGARIEIDGLA---------------
>tr|B8DR11|B8DR11_DESVM Multi-sensor signal transduction histidine kinase OX=883 OS=Desulfovibrio vulgaris (strain Miyazaki F / DSM 19637). GN= PE=4 SV=1
--SILLVDDEEGIRTVLGISLADAGYDVTTAASGEEALARFAAHRPDIVLTDIKMPGLSGLDLLERLKAAPEVEVIMLTGHGD-MDLIQSLKRDATDFLT
KPVNDDMLEVRARISMRQTENLEQMVRDQSAR--LVEAERQ---------L--AALQVMDGI---ASGIRSLCSALDD-------------GGLFNELPC
IVSTNQLYKERLGHRIGSRSW-----------EAYAGRGPGDRLCPVMRVLETGEG----------FRSN-----EVLLGRNGQEIPVIVNTAPI--YGN
DGEVELVLELSVDVSEVRRLREDLRLTRERFRQLFDESPCYVAVMDRDFGVVEANRRYREDFG----DPTGRRCHDAFAHRLAPCSGCPAGRTFDPHQAE
TARDGRQVNVLVWTAPLRDAEGAITEVMEMSTDITELRRLQDRLSLLLGSTAHGIKGLLTALDGGVYRLGSGIARGDVQDSH-QDIRHLVDRLRKMVLDL
LYYAK----NRELNWEVVVTRAFAEETAMLVEAKAT-----ERGVRFVRDFAADLGTFEADTGALSSALVNLLENAVEACKQDHAVTFRVRGAPEEVTFT
IIDNGTGMDRETREKLFTLFFS-----SKGTAGTGIGLFVASQVVRQHGGHIAVASEPGEGSTFTVSLPR---------------
>tr|F3YXT3|F3YXT3_DESAF Multi-sensor signal transduction histidine kinase OX=690850 OS=Desulfovibrio africanus str. Walvis Bay. GN=Desaf_1187 PE=4 SV=1
--KLLLIDDEEGIRRMLGMSLADLGYDVHTAADGQEGLKLFDWLAPDIVLLDIKMPGMDGIEVLRNIKARIDAEVIMISGHGD-LDLIKSLQLDAVDFVT
KPIRDEILQIRAKLSMRRTDNLERLVAEKSAR--VVELERQ---------V--AVGQVVESL---TEAMSALAGDIGN------------AAGPFNEIPC
IVATNRLYRERLGDKVGCNSW-----------EVYSGRLGRGNGCPVWMAIETGKG----------QRRR-----ELLVDRNGQEIPAIVHTAPI--TGR
DGRVEFVLEFSVDVTEVKRLQDELRTAQQKYQEIFDASPAFISVHGLDFRIREANRMFRECFG----AGVGERCFEAYKHRDRPCTECLVHKTVKTVETE
TDREGQPINVLIRTSPIRDEKGDIVEVMEMATDITQLRQLQDHLSLMIGSMSHGVKGLLTALDGGVYKVERGLAKGDVVEGW-GVVTSMVGRIKKLVLDI
LYYAK----SRHLNHESVEVAGFAQSLAEIVGPKAE-----RQGLSFGLDLAGSLGAFEIDEVALSSAMVNFLENAMDACKAGHKVVLRARADAEAVYFE
INDNGIGMDRETREKMFTLFFS-----SKGAKGTGLGTYISGRIIAQHGGRVRVESTLGQGTTIHVAVPR---------------
>tr|A1VH15|A1VH15_DESVV Multi-sensor signal transduction histidine kinase OX=391774 OS=Desulfovibrio vulgaris subsp. vulgaris (strain DP4). GN= PE=4 SV=1
--SILLVDDEEGIRKVLGITLADAGYRVTTAADGEEAMRRFAEERPDIVLTDIKMPGMSGLELLESIKSRSEVEVIMLTGHGD-MELIQSLKRDATDFIT
KPINDDVLDIRARITMRRTENLEDMVAKQSAR--LVAAERQ---------L--AALQVMDGI---ASGVQTLSRMLDQ-------------AGIFNELPC
IVATNDLYKERLGHKVGQPSW-----------EVYKGREGSGNGCPVWKVIETGEG----------QRSN-----EILIDKHGQEIPVIVHTAPI--LDN
DGEIEMVLEISVDVSEVRRLQDELRITRERYRQLFDEAPCYIAVIDRSLKVVDANRRFHHDFG----EPAARHCHDIFAHRLAACQGCPVERSFDPHQYE
TTGDGRQANVLVWTSPLRDAAGNITEVMEMSTDITQVRQLQDRLSLLLGSTAHGIKGLLTALDGGVYRLGSGLDRNDVRDSF-EDIRHLTGRLRKMVLDI
LYYAK----KRDLNWEVVVAERFATETAELVEGKAV-----NRGVGFQLEIAAESGTFEADAGALSAALVNLLENAVEACRPEHSVTFSVGGDANHVEFS
VRDDGVGMDRETREKLFTLFFS-----SKGSAGTGIGLFVANQVVQQHGGHIAVASEPGHGTTFTVSLPR---------------
>tr|C6BRJ1|C6BRJ1_DESAD Multi-sensor signal transduction histidine kinase OX=526222 OS=VKM B-1763). GN= PE=4 SV=1
--NIMLVDDEEGLRRFLGLTLMDFGYTVETAENGVEALKLLENFHPDIIVTDIKMPRMDGIDLLKAIKEDPHIEVIMLTGHGD-LDLIESLKNDAADFIT
KPVDDDVLELRVKIHLKRTENLEKMVEEKTSR--IVELERQ---------N--AACQVVEGI---TDALSNAAHEVES------------ESSMFNELPC
IVATNKLLKERLGDVVGKNSF-----------DIYSDRTSAGNACPVQLTFQTGKG----------QRSK-----ETFITEDGEEIPVTVYTAPI--PAK
NGEIELVLDISVDMTELQRLRDELLETQSKFQRLFDEAPCYISVQNKDYTIAEVNRRFKDDFL----EPIGGTCYSSYKHRDTPCDECPVQRTFKSHQME
TTKNGEQKNMLVWSAPLRNAYGEIKQVMEMSTDITEIRRLQDHLTFMLGSMSHGVKGMLTALDGGLYRLESGLRKNDVEDAT-KTLKDVVGRVKKMVLDI
LYYAK----SREIETETIGAGNFLRDTAALIATKAA-----AANVSYNIDIPKELGNIEIDTSSMSAALVNFLENAVDACDKEYSINISAREIADEIEIK
ISDNGSGMDQETREKIFTLFFS-----SKGKRGTGIGLFISNQTIEQHGGKISVESEPNQGTTFTILLPR---------------
>tr|Q30UY8|Q30UY8_DESDG Multi-sensor signal transduction histidine kinase OX=207559 OS=Desulfovibrio desulfuricans (strain G20). GN= PE=4 SV=1
--SILLVDDEEGIRTVLGLSLADAGYNVSVAATGEEALRLFDQSRPDIILTDIKMPGLSGLDLLKRVKNIPDVEVIMITGHGD-MQLIQSLKQDATDFIT
KPINDDVLEIRARISMRNTENLENKVREQSAR--LVEAERQ---------L--AAQQMMDGF---SVGLKALLNAMDS------------TGGVFNELPC
IIAANDLYREKLGNLVGHQSW-----------EAYYGRDKDSNGCPVLTAIREGRG----------SRTE-----EMLVDKTGKGIPVLVHTAPI--LDN
DGEVELVLEISVDTSEARRLHEELRLTRHRYGQLFDEAPCYITVQDKQFRVVEANRRFREDFG----DAVGGFCHEVFVHRQTPCTGCPVQRTFNPHQYE
TSRSGEQYNVLVWTAPLRDAAGNITEVMEMSTNITELRKLQDRLSLLLGSTAHGIKGLLTALDGGIYRLGSGLERNNVHDSY-EDIRHLTDRLRKMVLDL
LYYAK----KRELNWEVVLASHFAPEVAALVRPKAE-----AQKVRFTIEVAPDAGTFEADAGALSSAFVNLLENAVEACDKKHAVHMAVSGLPDRVEFC
ITDNGVGMDRETREKLFTLFFS-----SKGAAGTGIGLFVASQTVQQHGGSISVGSEPGKGTTFVITLPR---------------
>tr|L0RDQ8|L0RDQ8_9DELT Multi-sensor signal transduction histidine kinase OX=1121451 OS=Desulfovibrio hydrothermalis AM13 = DSM 14728. GN=DESAM_21429 PE=4 SV=1
--KLMLVDDEEGIRRFLGLTLIDLGYSVETAENGEAALKLLETFQPAIVLTDIKMPRMDGIDLLKAIKSDPHVEVIMLTGHGD-LDLIESLKFEAADFIT
KPINDDVLEIRVKIDMKNTENLERLVEEKTQR--IIELERQ---------N--AACQVVEGL---SEALSSAANEVET------------GSGLFNELPC
IVATNKLLKERLGDVVGYNSF-----------DIYSDRNSAGNACPVQLTFETGKG----------QRSK-----ETFISKDGEEIPVTVYTAPL--PNQ
NGDIELVLDISVDMTELKRLRDELLETQYKFQRLFDESPCYISVQNKDFSIAEVNRRFKEDFD----DPLGASCYSAYKHRDNPCEECPVQRTFTSHQME
TTRKGDQKNVLVWSAPIRNAYGEVIQVMEMSTDITEIRRLQDHLTFMLGSMSHGVKGMLTALDGGIYRLESGLRKNDVAEAA-KVLKNTVGRVKKMVLDI
LYYAK----SREIDVEKIEASTFLTDTAAIVAPKAA-----AANIKFNIDIPDDLGTVTIDTSAMSATLVNFLENAVDACGKEFEIGFSARDNGDSLSIV
VTDNGTGMDPETRDKIFTLFFS-----SKGKKGTGIGLFISNQTIEQHGGKITVESESGKGTTFTISLPR---------------
>tr|I2Q2I6|I2Q2I6_9DELT PAS domain S-box OX=596152 OS=Desulfovibrio sp. U5L. GN=DesU5LDRAFT_2326 PE=4 SV=1
--TLLLVDDEEDIRRFLGLFLADLGYVVHAAANGEEALAMFDEVNPSIVLTDIKMPVMDGLELLKRIKARPDTEVVMISGHGD-MDLINCLQYDAADFVT
KPINHDILDARIKLSLRRTQNLEKLVREKSSR--VVELERQ---------V--AAGQMVETM---CQAISGLSADFGD------------GAGYFNEMPC
VVATNQLYKERLGEMVGHHSW-----------EVYVGQALRGFDGPVWKTFETGKG----------QRSR-----ETMLCKNGRELPVMVHTSPI--ATT
DGKVELVLEMAVDVSEIKRLQEELRVTQQKYMDLFDATPCYIAVRGPDGRIVANNHRFAEDFG----ESVGRTCYDAFKHRSEPCPDCPAEATFAPHYQE
TTKGGQQRNVLISTAAIRNAAGEVVEVMEMSADITSIRQLQSHLTLMLGSISHGVKGMLTALEGAVYRVESGLRRGDAEAAA-EAVKTLVGRVRALVLNV
LYYAK----SRELAPETVDVAAFASGIVQTVAPKAA-----REGVILAAAIGQELGTMDVDVGNLSAALVNILENAVDACQKDRQIEFAVSREDGQVVFD
IADNGMGMDQETREKAFTLFFS-----SKGLKGTGLGLFIANDMVAKHGGTIDLTSEPGVGTHFRVRLPE---------------
>tr|E1JTZ0|E1JTZ0_DESFR Multi-sensor signal transduction histidine kinase OX=596151 OS=Desulfovibrio fructosovorans JJ. GN=DesfrDRAFT_1089 PE=4 SV=1
--TLLLVDDEEDIRRFLGLFLSDLGYAVHAAANGEEALAMFDEVAPSIVLTDIKMPVMDGLELLKRIKAMPDTEVVMISGHGD-MDLISCLQYEAADFVT
KPINHDILDARIKLALRRTQNLEKLVREKSSR--VVELERQ---------L--AAGQMAETM---CQAISGLSADLGE------------GAGYFNEMPC
VVVTNQLYKERLGDMVGHHSW-----------EVYVGQALKGFDGPVWKTFETGKG----------QRSR-----ETMLCKNGNELPVMVHTSPI--ATT
DGKVELVLEMAVDVSEIKRLQEELRVTQQKYMDLFDATPCYIAVRDPSGKVVANNRRFVEDFG----EGVGRACYDVFKHRAESCPDCPAMGTFAPHYQE
TTRDGRQRNVLISTAAIRNAAGKVVEVMEMSADITSIRQLQSHLTLMLGSISHGVKGMLTALEGAVYRVESGLRRGETQAAA-EAVKTLVGRVRNLVLNV
LYYAK----SRELDPETVDVAEFAAGVAQTVAPKAD-----REGVTLTSEIGENLGVMAVDAANLQAALVNILENAVDACKPEHHIRYRVRREGATLVFD
IEDNGMGMDQETREKAFTLFFS-----SKGLKGTGLGLFIANDMVAKHGGVIDLTSEPGLGTRFCVRIPE---------------
>tr|C8X162|C8X162_DESRD Multi-sensor signal transduction histidine kinase OX=485915 OS=Desulfohalobium retbaense (strain DSM 5692). GN= PE=4 SV=1
--ALLLVDDEEGIRKVLGITLADSGYTVHTAANGNEALEVWREHRPGIVLTDIKMPGMDGLELLQALKAEPETEVIMITGHGD-MDSIESLRNDAADFIT
KPINDEVLEFRVRIRMRRTQNLENLVREKSQR--VVQLERQ---------L--AVGQVVEAL---GSAVAGLSREMDH------------GDPVFNELPC
VVATNALYAERFGDRSGKPSA-----------EVYCGQAASPDECPVGRTLATGQP----------QRFQ-----VTACSAEGRELPLMVHTAPV--RNH
DGDVDLVLEISVDVSEITRLRDELRFTRQRYQQLFDAAPCYISVQDMDLRIAETNDLFKQDFG----DFSGEYCYQVYRHRSRPCDNCPAFETFEPFHTE
TSRTGERYNVLVWTAPIRDTSGEVVQVMELATNITQIRQLQDHLTMLLGSVSHGVKGMLTALDGGIYRLESGLKKQDISSAS-QVIKKQVGKIQRMVLDI
LYYAK----SREINWDVVSARELAEEILDTAGSRAE-----QAGVRLHSDIQEDLPKFEADPTAVSSAVVNFLENGVDACADP-QIHFSVESTKDHVVFS
VEDNGPGMDQETQDKIFSLFFS-----TKGNKGTGLGLFIANQVIEQHGGRIEVSSELGNGTRFIIRLPR---------------
>tr|F0JEM8|F0JEM8_DESDE Multi-sensor signal transduction histidine kinase OX=641491 OS=Desulfovibrio desulfuricans ND132. GN=DND132_1550 PE=4 SV=1
--KLLLVDDEEGVRRFLGLSLMDLGYEVETAANGQEALDLFDSFRPHIVFTDIKMPVMDGIDLLKAIKERPDTEVVMITGHGD-MDLIESLKFDASDFIT
KPINNDVLEVRARYSMKLTENLEKLVQEKTDR--IVELERQ---------N--AACQVVQGM---STALSDAAQEVET------------GYGLFNELPC
IVAHNRLFEERLGNQVGNNSF-----------DIYSDRTSPGNACPVQRTFNTGKG----------QRSK-----ENFLGKDGEEIPVTVYTAPL--PNK
DGEIELVLDISVDMTELKRLQDELYTTQYKYQRLFDEAPCYITVQDADLNIVEANRLFKRDFG----EVEGHFCFEAYKHRDEPCEGCLVDKTLLSRQRE
TTLSGEQKHMLVQAAPLHDASGRIFQAMELSTDITEIRRLQDHLTIMLGSMSHGVKGMLTSLDGGIYRLESGLKKGDVDAAT-KTLKSMIGRVKKMVLDI
LYYAK----SRELETEAVDAAKFLNDTAEVGAARAA-----AHQVEFVRDIPDDLGAIQADTAALSAAMVNFLENGVDACGR---LTLSARRTDGGLVVT
VSDNGMGMDRETRDKIFTLFFS-----SKGKRGTGIGLFISNQTIEQHGGSIRVESAPGEGSTFIITLPR---------------
>tr|C6BWG9|C6BWG9_DESAD Multi-sensor signal transduction histidine kinase OX=526222 OS=VKM B-1763). GN= PE=4 SV=1
---ILLVDDEPDIRDLLGILLADLGYEVRSAENGEAACKSFRCNPPDIILTDIKMPGMDGIELLRTVKKEPEIEVIMISGHGD-MQLIESLKLNAADFIT
KPIDDDILSIKVKILLRRTENLEQMVEEQSAR--MVELERK---------V--AVQQVVEGL---SSAMGIISGDIND--------------GLFNELPC
IITSNELFTNRFGNLNGESSR-----------SIYKDFSGQ--SCPVYQAIATRSG----------GRGN-----ATLIAEDGSEIPAVVYTAPI--TCS
RDKISLVLEVAMDVSEVNRLRTELVQTQKKYEHLFNQVPCYITLQDRDLRIVEANERFRNDFG----FDRGTHCHQAYKNREEECEDCPVRKTFDFHQNE
TTKNGEQYNILVWTAPVFNDAGEVEHVLEVSTNITMVRDLQDQLTMMLGSMSHGIKGLLGALDGGIYRVDAGLKKQDIDKGW-KVVKHRIGHMKKMVLDT
LYYAK----TRDLDYRPIKLGDFAAYLAETIAPKAA-----EHDIRLIRDFSHSDQIFHADPDALAPALINFLENGVDACKTEHAVTFCVYVSDSEVHFK
ISDNGTGMDRETRENMFSLFFS-----SKGANGTGIGLFISNQIIERHKGTIEVESTVGTGTSFHIRLPS---------------
>tr|K6GA60|K6GA60_9DELT PAS domain S-box OX=1206767 OS=Desulfovibrio magneticus str. Maddingley MBC34. GN=B193_3348 PE=4 SV=1
--RLLLVDDEEDIRRFLGMFLADLGYEVHAAENGAQALEMFDAVNPSIVLTDIKMPVMDGLELLKQIKAKPETEVVMISGHGD-MDLIGCLQYDAADFVT
KPINHDILDARVKIILRRTQNLEKLVQEKSRR--VIELERQ---------L--AAGEMVETM---CQAISGLSEDFGD------------KAGYFNEMPC
VVATNQLYKERLGDMVGHHSW-----------EVYVGQAIRGFDGPVWKTFETGKG----------QRSR-----ETMLCKNGRELPVMVHTSPI--GER
DGKVELVLELAVDVSEIKRLQEELRVTQQKYMDLFEATPCYIAVRDRDYRIVANNTLFKQDFG----EGVGKLCHEVFRHRDTPCPDCPVDATFEAHSLE
TCRDGRSKNVLTFSAPIRNAQGEIVEVMALSTDITQIRELQDHLTLMLGSISHGVKGMLTALEGGVYRLESGIKRSDIADAG-DTIKSLVGRVRNLVLNV
LYYAK----SRDMAGDPVDVSHLAGNVAQIVEPKAA-----REKIAFTCDIPPDLGTADLDTANLSAALVNILENAIDACKETHAISFKASADADAVTFD
IADNGMGMSQETREKAFTLFFS-----SKGLKGTGLGLFIAHDVVKKHGGRIDLTSEAGEGTQFHIVVPR---------------
>tr|E6VW72|E6VW72_DESAO PAS sensor protein OX=643562 OS=Desulfovibrio aespoeensis (strain ATCC 700646 / DSM 10631 / Aspo-2). GN= PE=4 SV=1
--PILLVDDEEGIRTVLSITLKDAGYEVDAAANVADALELFKSRQYPIVVTDIRMPGMSGVDLLREIKRIPRTEVIMISGHAD-IDVIQSLKYDASDFIT
KPINLDVFSFRARSNMRRTCNLEELVERKSAQ--LVEVERR---------V--AARQLFEGL---TASLDAFASNLDN-------------LSMFNQMPM
VVAINDHYRERLGNLVGEKSW-----------AMYDDLGDGEQECPVARTIANKAA----------RRAE-----HVVRCINGNRHSVAVDTVPI--TAS
DNEVELILEFMVDLREAEQLREELRTTQHKYQQLFDQTPCFISVQNRNFTILSSNARHKEGLG----DLEGGLCYERIMHRASPCRDCPLIKTFEMHQME
TNRKGEQINVLIWSAPIRDTSGAITEAIEMITDITQIRKLQDRLTLLLGSTAHGIKGLLTGIDGAIYRLGAGLENKNVEDGF-TDLQFLTGRMKQTVLDI
LYYAK----KRELNWKVLDVATFALNTYTSMSTKAE-----AKNVLLELDLAKDLGSIKADASILASALGNILENAIDACDAPGNVLFKIYGDANQVAFQ
ITDNGAGMDHETRDKLFTLFFS-----SKGIAGTGIGLFVANEIVQQHGGSISVDSEQGHGSTFIVTIPR---------------
>tr|C4XML1|C4XML1_DESMR Two-component hybrid sensor and regulator OX=573370 OS=Desulfovibrio magneticus (strain ATCC 700980 / DSM 13731 / RS-1). GN= PE=4 SV=1
--KVLLVDDDEAIREVLSLSIADLGYDVETAPGGREALELCATFKPSIVLTDIKMPGMDGIELLSRVKALPEIEVIMISGHGD-MELIESLKRQALDFLT
KPVRDELLTARARVSMRRTRNLERLVREKSAR--LVEMERR---------M--AVGQAVEGV---ASAIEGLIASFDQ------------GPSYFNQMPC
IVAVNTLGRQRLGEVVGKMSW-----------ELYADRQGSGNACPVWRTVEQGQG----------QRGR-----ETFRDKDGREIPVLIHTAPV--FGT
DGQVELVIEIAADVAEVGRLQEELRAVREKFQRLFDAVPCAIAVLDQDFTVVEANRQWRADFG----EAETGPCHKLFAHRDDPCEHCPAESSFHPHEGE
STRCGAAKNMWLRTAPIPDATGETSQVIEIAADITPIRALQDHLALMLGSMSHGVKGLLTSLDGGMFKVETGLSREDVRDGW-GVVSDKIGRIRNMVLDI
LWYAK----SREPELSPVSIETFARDLAGIVEPKAQ-----SRDVAFILRLGEAAGTLPMDETALTSAMVNLLENAVDACKAFHEVTLTVEATAEAVTFV
VADNGVGMDQSTRERMFTLFFS-----SKGSRGTGLGLFIANQIVAQHGGSIAVTSEPGVGSAIAVRLPR---------------
>tr|G1UZU1|G1UZU1_9DELT Putative uncharacterized protein OX=693988 OS=Bilophila sp. 4_1_30. GN=HMPREF0178_00788 PE=4 SV=1
--TILLVDDEQGIRTVMGLSLRDAGYNVITVASGEEALQLFAERPIPIVITDIRMPGMNGLDLLKHIKILPETEVILISGHAD-LEMIQGLKLEASDFIT
KPIDDDLLHIRARIAMRNTSNLEKMINEKSAQ--LVEAERQ---------L--AARQVVDGF---AFGLHTLGSSMSG------------EQQAFNELPC
VLAVNDLYRERLGNLVGHPSW-----------EPYV-LHSNEAMFPVERAIVEGRG----------ARSE-----QILRDKNGKEIPVLVHTAPI--LNN
EGEVELVLELSVDEQESRRLREELRVTRERFRQLFEESPCYVSVVGRDLQVLEANRAFRHTFG----MQSGKRCYELFAGSSAPCDECPVQRSFQPCHTE
IDHEGRPVNVLVWTAPLRDTSGNITECIEMATDITELRQLQDRLALLMGSTAHGIKGMLTALDGSVYRLGSGIDKGDTRDSL-KDMRQLVARLRKMVLDI
LYFAK----ERKLDWNILVAEEFMRSVVSTVSDKAA-----EAGIAMTLEADGDPGTFEADASALSAALVNLLENAVDACKKEHYVRVSVKGLSDAVEVR
IEDNGIGMTEETRTKLFTLFFS-----SKGKGGTGIGLYVARQVVMQHGGRIEVASVKGEGSTFTVTMPR---------------
>tr|H8KTN4|H8KTN4_SOLCM PAS domain S-box OX=929556 OS=NCIMB 12057 / USAM 9D) (Flexibacter canadensis). GN= PE=4 SV=1
--RILVIDDNADMRNYIT-NLLLPYYEVSVAINGKDALQKISKNLPDIILSDVMMPVMNGVELLHQLKNTASVPFILLTARAGEESKIEGYEMGADDYLI
KPFSAQELIARIKSQLRITRYRSHIFEQRNLFKGKDRFELMNERMQ--EMFQKKEA-EV-LNKPAFNIFPEAAYQTG---ERVILHELFYLKVIYEPLRE
EDGSIVLSRKRIEDSEKHYRELISE-----------SPMAIAILSGPEMEVEFANKTLTKFFPLTQLFRKNFSKELDYV----FTTGNHYYGHEIKLRLK
TEIKDLVFQPNILANEVALIKENIIKSEKELQQLSNAMPQLVWIANQQGDIYYYNNRIEEYNHTEKS---AHYKWETIVHQEDIEFTRQRWNNKIPYEAE
LRMADGSYKWHLAFPQLNENNEVWYGTATNIDALTVQLMLKRINEQFAYITSHDLQEPLRKIRVFSNLILDNEQLSEPTKKYLQKIDVSANRMSDLIKAI
LNYSQLERP-E-ESFTLVDLNQLLSATLENLEVLIQ-----EKKAVIKSAI---IPPIKADPLQMQQLFMNIIENGLKFSNPPTHINIKSTIHQRYLKLD
FEDNGIGFEQKFAPLIFTIFQRLH---PLDYKGTGIGLAICKKIVDNHHGFIKVSSVVNQGTVITIFLPL---------------
>tr|F8EBS3|F8EBS3_RUNSL Multi-sensor signal transduction histidine kinase OX=761193 OS=NCIMB 11436 / LSU 4). GN= PE=4 SV=1
--TVLVVDDNADMRDHIQ-TLLRKTYHVITAKNGREALDLLPSVNPALILSDIMMPVMDGIQLLKEIKDTAQLPVILLTARAGEESKIEGYETGADDYLV
KPFSSKELLARISSQLKIASTRKHIEQQKNLFRGPQVVEIANARVL--AIWGKKAS-EI-VGKPIFEAIPEAVYHNG---TPCLVNETVYLKFVFEPLRE
ETGVVVKARKKIEESEQRFRNL------------------------------------------------------------------------------
----------------------------------AETLPQLVWVTDEKGNQMYVSSRWKEYTGIEPN---NEETWRVIVHPDDLDSTGKAWMTGKRYKQE
LKSKTGQYRWHASEPVVENDGRIWVGAFTDIHTENEQRELEQMNQSFAYVSSHDLQEPLRKIQTFSSRILEEKNLSETGKNYFSRMQNAAYRMQVLIDDL
LAFSRISST-E-RKFEHLSLSLIIDEVKTEFHEVIQ-----EKNAIIEYNE---VCEAHISPFQFRQLMQNLIGNSLKFTMPPPHIIIKSEINKKYCCIT
VSDNGIGFEQRFSNRIFEVFQRLH---GRDYEGTGIGLAIVKKIVENHNGVISATGVLNEGATFTIYIPH---------------
>tr|A4BZQ5|A4BZQ5_9FLAO Sensory transduction histidine kinase OX=313594 OS=Polaribacter irgensii 23-P. GN=PI23P_08480 PE=4 SV=1
MFKILIVEDTLAIREEVCDILLLEGYQVFQAENGETGFYMALQELPDLIVSDILMPKLNGFEMFEKLKKTSGIPLIFLSAKGEKEDVRTGMNAGAEDYLV
KPVNTEELITVVKRKLEKQFLIEKLVKE-------------------NEYVLKEAGRMAKIGYWEFDQKTKITSWSKTV-------HTIYGTDPREGVPS
E-----KILLNCFDEVSKQQFLNARSSLAAHGKLYDIELKITNLKN------------------ENRWIQRVGEPLYNH--------------KKEIIG-
------SRGIIRCITNLKKNQEKLKQSNERYHLATKATNDAVWDWNLTGKIYRSAVGFDKVYGFDKKRPIKANWNAYIHPDDKNRITKLLEKIIAS-SDQ
NNFTGDYKYINDRGFIVRNEDGKAIRIIGAASNITKREEIKGFKDQFLANMSHEIRTPLNGIIGFTKILLRDNATKKQR-HQLNAIKTSSDILLVVVNDI
LDLSKIEAGKMILEKTNLKLPNLVNSVLSTFELRIGE-KEQTLNTRFDKNIPK---WLIGDTVRINQILLNLIGNALKFTAVGGTINVHLNQDEVNVEIS
VSDTGIGIPSDKIKNIFDPFIQSSDNTARKYGGSGLGLNIVKQLIDLMHGSISVKSQESIGSTFTLTIPL---------------
>tr|E0UIX4|E0UIX4_CYAP2 PAS/PAC sensor hybrid histidine kinase OX=497965 OS=Cyanothece sp. (strain PCC 7822). GN= PE=4 SV=1
--RILLADDNADMRDYIKRLLTD-LYEVETVSDGIAVLEALARELPDLVLTDVMMPGLDGFELLRELRATRQIPIILLSARAGEPSRVEGLKAGADDYLI
KPFSARELLARVETHLKMAQ-----IREENAHREQ-QLRINILETITDGFFSLDHQQETELGHSIWEVYPHIYPHQGQSETADAMPQIVWITNAAGKVEY
LDYTAEQIRSAINQTPYQSEFRLRRGRDGSYIAWYGTSTDIDDYKQAELCIRIASSPIGISFFLCYLYVNQAQQPLLN-HEFMGEIIPGNFRHCLACLPD
GEVLGIGVTVKQVEAALRASEATATERAQELETLMEITPVGLIAHDPDCHSMSANQTAYQLMQAKPGDIAGTYPLNFQRNGKEDDLPMQVARSGQEITDE
IEFDGTVRFIYGRAIPLTNESGQIRGVIGAFVDITEQKQLERIKDEFLAVLSHELRSPLNPILGWAKLLQTQNFNAETYQKGLSTIERNAALQAQLIEDL
LDISRIMRGKLNLKIVPVNLIFIIESALETVRLAAE-----AKTINIQKDLDLTVGKVLGDTARLQQIVWNLLSNAVKFTPTGGQVNVKLEGSGNEAVIT
VSDTGQGISANFLPYVFDYFRQADSKTTRKFGGLGLGLAIVRHLVELHGGTVTANSPENQGATFSVKLPL---------------
>tr|G0LG39|G0LG39_HALWC Receiver/sensor box histidine kinase OX=768065 OS=Haloquadratum walsbyi (strain DSM 16854 / JCM 12705 / C23). GN= PE=4 SV=1
--LVLHVDDDPSVTDLTGRFLEREDFSVETAISATEGLERIIECSQDCVVSDYDMPEMDGIDFLQTVREEPNLPFILFTGKGSEEIASDAISAGVTDYLQ
KQPEQYELLTRIQNAVQTQHQRLTEFA-GDTGGFEI--VDTGEVLMTDGC-RRLVGLADATLKEAIKLYHNRAADTGEQTQGSWAIPSQSEGKTDTDITI
LRGAIHQREQQLTELNRVSKDLLTGVTAARDVLDFQANALHLSVDELMSLL-------DEVPEIGRAYQRGEPDIIEDARQHPNANPTTNLRGHVFPLAE
HGIGEL------LAGALVAALDRLDRRAKELSLFFEESPLGAVQWDDKCQFKRVNRQAEEILGYSESE-LRGESWELIVAD---RVGNAVDSFLNA----
---DGGSHIITLTNRVVTDADGVFSSFEDISARRTELQEYKQELAEFTGIVSHDLRNPLAVAEGHLELA-MTQTQDVGNGNHIIKARHAIERCQRLIEDL
LTLARDG--DRVDDIEPIRFDTMIEECWETVET---------TTATLTIADQR---SIKADKSRLKQLLENLYRNAVEHG--GDQVIVSAGIMSDGFY--
VSDTGPGVPKSAREKIFNAGY------STAENGTGFGLRIVKQVADAHGWEIDVTNDTEGGARFEFT------------------
>tr|Q5V0Q2|Q5V0Q2_HALMA HTR-like protein OX=272569 OS=B-1809) (Halobacterium marismortui). GN= PE=4 SV=1
--RLLHVDDEPDFAETAAAFLEKENLRVETASNAENALERLESSTFDCIVSDYDMPGRSGIEFLEAVREEPELPLILFTGKGSEEVASDAISAGVTDYLQ
KEADQYTLLARVQNAVEARQSALEQIL-KTVPSCVVQLRDGQFVFANQRA-IDVLGLSSELKDPEWEIRDRQVLEGQPLSDARHGTEKVVNGAPFGAVES
VVCTLTDRKRDLQETERRLQLALEASETGVLEWDYETDEVVLS-DTLERLL-------GFEPGFGTVFELIHPEDRTEVREQIERVETDSVYDGERMIDA
DGDSTL------MVGVHHDITEHKEVIERRLEAILENTTTPMFMKDDEGQYLFVNHGYRELTGLADEEIVGRTDFELFPEETAEAVLQAGQPIETEEQL-
-IIDGETLQFR-SDPDTPV-----AVF-GVASNITDIRKQEQELAEFASVVSHDLRSPLSVAQGRLQLA-RTTGDE----SHLEGIETALDRMERIIDDV
LLLARQG--QDIQETAPVSLHDAVADAWEMVSQDA------EDGTLAFTDTDKRDVTITADRPRLLQLLENLLRNSVEHG--ATSVNITVGAIKGGFY--
VADDGPGVPEDERETLFEAGY------STADNGSGFGLAIVDRIAEAHGWAVDVAESADGGARFEIT------------------
>tr|C7NMD6|C7NMD6_HALUD Multi-sensor signal transduction histidine kinase OX=519442 OS=Halorhabdus utahensis (strain DSM 12940 / JCM 11049 / AX-2). GN= PE=4 SV=1
--RGLHVDDDPEFTDLTATMLEESYFQVETATSGREGIDRVSSETFDFVVSDYEMPGVDGIEFLKTVRESPDLPFILFTGKGSESVASDAIAAGATDYLQ
KTGEQYDLLARVANAVEQYRE-LEGIR-TIVNQVNQALRASTRDWIETQV-CEILGIDQPIRAASDGMQSHEVVQVGTESDGSFGLLVVTRPQADQSFLA
LGDDIADVRHELERERKFIDQALDAIEDIFYVIGPDGTLRRWN-QQFREVT-------GYSDEIGMAVEFFPEDERHKVDGAIECLSQGRQMTEADLLTA
EGTPGI-------VGIGRDVTDRQE-TLRRYKQMVNAMQESACIYDEDARFEVVNEYLAEFYGTTRED-LEGSPSTLIPQIRDQPFQDLIDGTREEVRG-
-ELEGE----EVLTPLVVDGE--IDGVVGVTREVTERRDRERELESVANIASHDLRNQLSVARSRLELA---AIDD----EHADPIRRAHDRMESLLADL
LALARRG--KRVEDTEHVGLEPIIRESWDHVET---------PTATITVTATG---TLEADPDRLRRLLEALFENSIEHG--GESVTVTAGDLEDGFF--
IADDGPGIPEDGHERVFDPSY------STAENSTGLGLTIVQAIADAHGWTVEATESADGGARFEIT------------------
>tr|G0HRB1|G0HRB1_HALHT HTR-like protein OX=634497 OS=102182 / NCIMB 2187 / VKM B-1755). GN= PE=4 SV=1
--RILHVDDEPGFADMTATFLEREDLDVQAATSVAAGLEILTDTDIDCVVSDYDMPDRNGIQFLETVREEGSLPFILYTGKGSEEIASDAISAGVTDYLQ
KQSDQYAVLARITNAVESQRVKLDAIE-TAQEGISIL-EDGTFIFVNEAY-ADLYGYEDEMVGEHWELLYDEIVP--TVDETGYGTTTGADGSTTVLART
LVCTVRDGEEELSRIKRAMDEAPVGITITSPEQD-DNPITYAN-RQFLELT-------GYTESVGRNCRFLQGEETEEPVDAMRAIDADEPVSVERNYRK
DGTGTVV----NYVGFQQDITERKE-HEHRLRALSESVQNLLQADTREE---VAEIGVDTACTV-----LGLEANTIHLYDEGDAASDAIYDLLDDLPT-
-FTPGGSIAWALANPDTPIKSELGEILAGHVTSTEQLRDHQQELEAFTSVVSHDLRNPLTVAEGRLELA-REECES----EHLAAVERAHERMDTLITDL
LTLAQDG--ETVTDREPVALASLVEDCWTNVET---------ADATLVTDIDR---TVLANESRLKQLFENLVRNAVEHA--GADVTVTVGAVDDGFY--
VADDGPGIPEADRDTVFEVGY------STSTEGTGFGLSIARKVAEAHGWEINVRDSADGGARFEVT------------------
>tr|E7QPR5|E7QPR5_9EURY Putative signal-transducing histidine kinase OX=797209 OS=Haladaptatus paucihalophilus DX253. GN=ZOD2009_03867 PE=4 SV=1
--RVLFVDPLSDAGVFPDR-LADAILSVVEARTTDEALDVLSERRIDCVISAYALPDSDGIELLHAVRQTLNLPYILCTESGSEKIASRAISAGVTEYLR
--ATDPETLARVERIVSPSETSYRSIV-QAMGDGVYTLTNGRMTAVNDTL-VDISGYEDELVEHISMLLDRGLIRNDAVGQLQAPCEARTHNDVRGVFRS
IEEHEHDEKRRIEELHEVASEMESTVDAAESILQFDICGVDLIESTGMTND-------GYSKEIGKTHQNNETYVIDDVREESDAPAQAEYRSLLVPVGD
EGIAEL------LVSHTAEALRRISESEEKYRTLVEQSHDAIYIYRNDS-FEFINQRVCDLTGYTRDELMEMEIWDLIHPD---EVKHIASGRSRG----
---EHSPHYEIRHVRIITYEG--KHAHLGSARDVTGRKKRKQELEEFASVISHDLRNPLNVAQGHLELA-KERGED----RHFEKSESALDRMESLIADL
LTLARQG--QVVSETEPVELPTIVRQAWSNVET---------GDRTLIVDTLG---TVDADPGRLQELFENLFRNAVEHA--GDETTVRVGELADGFY--
VEDDGPGIPPEERDAVFEHGH------TTAKSGSGLGLSIVKGIANAHGWSISVSDGSDGGARFRIR------------------
>tr|Q3IM66|Q3IM66_NATPD Receiver/sensor box histidine kinase OX=348780 OS=Natronomonas pharaonis (strain DSM 2160 / ATCC 35678). GN= PE=4 SV=1
--RVLHIDDEPDFAEVAAELLEKQDFDVEAVTDSDEALARPIGTEFDCIISDYEMPERDGIELLKRVRDVPELPFILFTAKGSEEVASEAISAGVTDYLQ
KGASQYTVLARIKNVVNQHRSQLTQLA-ERTDDLLFIFSHNEIGFINSAY-EDIWGRDASLRDPGQLLKSSQAVEAGTSDAVEFGEIRWSELKPSGTVVR
IVGVGRERQRELERVKQRYQALLENTMDVTTVLDGDGRISYQS-PAVERLL-------KYEPEMGDVFDYIHPDDREHVTQQFTEIEQSETATKRRLQHS
DGTVDG------YVFNSRDITAREE-YRQRLETMLENLPGYVYRHRDKSEYPFVKGSVEAVTGYTSAELVGLAEEIIHPDDRADAESDENESYEHTYRI-
-LTKSGDTRWRVQDPVSGD-----PKLEGFITDITDQKERERQLDEFASVVSHDLQNPLSVAQGRLELM-RTEYDS----EHIASLDRALTRMETLIDDL
LTLAREG--TRVQETGAVDLAELFEQCWQSVST---------AGATLHTQLDR---TVHADRNRLAQVLENLYRNAVEHG--GSDVQVTAGELDDGFY--
IEDDGAGIPVAERENIFESGH------ST-NGGTGLGLTIVRQIVEAHGWEISVTDGTDGGARFEIT------------------
>tr|A9GA45|A9GA45_SORC5 Two-component hybrid sensor and regulator OX=448385 OS=So ce56)). GN= PE=4 SV=1
-------------------------------------------DVPDVLVLDQVMPGMSGTEICGLLRSTVGLPILILTVAGQEEDLVEGLTAGADDYVV
KPCPAAALSARVGALLRSKRLRERAERAERI------------------------------AAVERDLLRALIEQSGDGI---------MAADACGALRI
CNVYERDARDALEGRPLRPDEDLHRA-------------LRGE--KVENAR---------------WLVTRPDGSIRALSGTASPLADGSPAGAVLIT-R
DETDAI------------EAERALRDSEERYRVIISALEEGITLQDERGVIRTANASAERILGLPMAQLVGSTMMGVREDGSPFPLEQIALRTGAPQSGV
LRLDGSVLWLSVNAQPLRGEDGSVAGVVSSFFDITARKRAEEERQEFLATMSHELRTPLTAVLGWVRMLRTGKLPEERRDKALETVERNAQAQAQLIDDL
LDISRIMAGKLRLDVHRIELVPVIDAALEVVRPAAD-----AKGVRLLSLLEPGVGAVAGDAGRLQQVVWNLLNNAVKFTPRGGVVRIRLDRADGSAEIT
VSDTGQGIEPAFLPYVFEQFRQAESGTTRRHGGLGLGLTIVKSLVEMHGGTAHALSDEGRGATFVVQLPLA--------------
>tr|B8FKA0|B8FKA0_DESAA Multi-sensor hybrid histidine kinase OX=439235 OS=Desulfatibacillum alkenivorans (strain AK-01). GN= PE=4 SV=1
--TILTIDDEEAIRQSFAAFLEDFGYEVLSAPNGKVGLEIFKEKKPHLILVDLRMPEVDGLEVLSSVTQSPETPIIVVSGTGVIADAVEALHLGAWDYIL
KPIKNLSILERRREHLERSKKI----LEYSNRDKTRQFTI-----------------KQSIEDLAPTILKTLSENIGVAGGSLFLLELIYALDPGHQKRV
IP------------LPP-PPRSVTAH-LFEQKEAFIVPDIHTD-ERFGWS--------------GYRNGSLMALPLRDSEGEIQGVTLHNKLKPPFTEQD
LELADIIASHSMAIRNINSNM-ALRESEQRFREVVELSPYPIAIVGPDRKHTLLNDKFTELFGYTMEEVPTMDAWWE-KAYPDPEFRAAVKKHWQMTMNG
VAIPEDDPILQSARTVESKIIPIGESNLIVMNDIKREIQLRQAQKTLAGGIAHDFNNILSPIIGYTEMAMVEVAENSTMERNLNEVMKAAERAKELVFQI
LTFSRQTEIEK----KPVQAQLVIREALKLLRSSIP------ASIQFEKKINKECGPVLADPTQIHQLLMNLCTNAYHAMGSGGVLTVEFDENGKYVRLT
ISDTGQGMTQAVQEKIFDPYFTT-KAQG---KGTGLGLAVVHGIVKSMEGDIRVDSKPGQGASFIIYLPQV--------------
>tr|K0NIL2|K0NIL2_DESTT Two component system sensor histidine kinase, hybrid, associated with CheB and CheR OX=651182 OS=Desulfobacula toluolica (strain DSM 7467 / Tol2). GN= PE=4 SV=1
------MDDNPENLFVLEKILKKLDADIIRAVSGNDALSTTLYNEFALIILDVQMPEMNGYEVILKDDETENIPIIFVTAIDRNAKEIKGYSKGAVDFIF
KPLDEFILMSKVRSGLERTLELERANSDNNARETTQGLTG-----------------CIEISSFGPKLLEEFASHMTASGGSLYFLRLLHCLDPGHAPDY
LS------------FPL-DEFSILRQ-VLESGKPSLVDDVAKN-DTIGWG--------------GYLDGSLLVFPILGTSRKVSGVTLHSKTQPPFTEQD
KEIGIILASYSCTMRAVEAFE-ALQKSERQYRTLFEKTNDAIFIAEATGRYTDANKAALDLTGRTLDELKQMTTRDI-TSKDADNLLAAISESCEVRELG
RVTYYRPDGT--CRIAKLSSVPLNTKYVIGIA---REKQLRQAYKTLAGGIAHDFNNILFPIIGYTEMLQQDIPENSPFRDSLDKIYSGGMRAKDLVKQI
LTFSRQRSGKL----KLMKMQPIIKEALKLIRSTIP------TTIEIKQDINTDCGEVKADPTQIHQIVMNLATNAYHAMETGGEMNVNLNQSGLYACLT
IADTGTGMNKDLIEKIFDPFFTT-KKKG---KGTGMGLSVVHGIVKSMEGSIRVDSMPGKGTQFYVYLPIF--------------
>tr|G7W579|G7W579_DESOD PAS domain S-box OX=768706 OS=VKM B-1628) (Desulfotomaculum orientis). GN= PE=4 SV=1
--KILIVDDRKENLLALEAVLKSPDYHLVFASSGEEALRCLLKDDFAVILLDVQMPGMDGFETAKLIRKNEDTPIIFITAIYSSENITQGYSLGAIDYLF
KPFNPEMLKFKIKIHLRKAEALAGVIGETSIN---SVITLGNVINSNPA-VLEMFGYEH----G--EL---LGKHVSVLFAEEC--------SYLPNL--
KNSPIICERSKIPEAAAKH----------------------KNGRIFPAEIQ---IGLASLEDQIFVWSVRDITERKQLEKE--RIDRYKTLETLVFERT
SELFQTNEKLKKIAKQ-------LRETSLKLTNILESITDVFFTLDHQWRFIFVNEEAEKYWLKGRDELIGNNIWDL-FPEARYLFNKALKNTEAA-HFE
IR--GYHTDV--PYEVHAYPSE--EGLSVYYHNIFERRMFEKERLQMAAGIGHEIRNPLTTVKGFLQLL--GGKEEFQSKGYFELMIEELDRANSIITEF
LSLAKNKT----VDLKPLILNELIENLFPLIQADAM---VSDKEIKLQLQ---DVETLPLNEKEIRQLILNLVRNGVEAMSKGGALTIRTFMEGEEIVMA
VQDEGCGIKDEDLEKVGTPFFTT-KE-----NGTGLGLATCFSIAARHNAKIDIDTGS-TGTTFFVRFKTP--------------
>tr|J7ITP2|J7ITP2_DESMD PAS domain S-box OX=768704 OS=13706 / S10). GN= PE=4 SV=1
--KILIVDDRRDNLLALEAVLESPDYHLVLAMSGEEALKCLLKDDFAVILLDVQMPGMDGFETAKLIRKNEETPIIFITAIYSTENITKGYSLGAIDYLF
KPFNPEMLKFKIKIHLRRAEALARIIGETSTD---TVITMGRIINTNPA-IKTMFGYEH----E--DL---LGENVEVLLPDNN--------FPFHNS--
LNNFVLCQSSKILNATAKH----------------------KTGRVFPVEIQ---VGVASIDEEILVWSVRDISERKQLEKE--RIDRYRTLEKLVLERT
GELFRTNQKLKEIGEE-------LRKTSLRLNNILESITDVFFTLDHHWEFIFVNEEAEKYWLKGRDELIGKNIWDL-FPEALPLFRKAKLKKEAI-HFE
IK--GLYSET--PYEAHVYPSE--EGLTIYYHNIMERKMFEKERLQMAAGIGHEVRNPLTTIRGFLQLM--EGKDEFKSKGYIKLMIEELDRANLIISEF
LSLAKNKT----VDLRPLNLNTLIENLFPLLQADAM---VSDKNIKTELQ---DIEVLSLDEKEIRQLILNLVRNGMEAMSRNGTLTLNTFMDGDRVVLA
VQDEGCGIKDQDIEKLGTPFFTT-KE-----SGTGLGLATCYSISARHNAQIDIETGN-SGTTFYVKFKTK--------------
>tr|H5XS06|H5XS06_9FIRM PAS domain S-box OX=768710 OS=Desulfosporosinus youngiae DSM 17734. GN=DesyoDRAFT_0425 PE=4 SV=1
--KILIVDDRKENLLALEAVLTSPDYQLMFASSGEEALRCLLKDDFAVIILDVQMPGMDGFETARLIRRHEGTPIIFITAIYSAENIKQGYSLGAIDYLF
KPFNPEMLKFKIKLHLRKAEALARVIGETSID---SVITMGSVIRSNPA-ITAMFGYEQ----E--EL---QGQHVSILFPKDY--------VDFLN---
ENALVMSKRRKIQDAVAIH----------------------KNGMTFPVEIQ---IGRSSIEGQIIVWSIRDITERKQLEKE--RGDRCKTLERLVQERT
CELFQTNEKLREVGKK-------LIETNLRITNILESITDIFFALDFEWRFIIVNKVAEKYWQKDRKELIGRIIWEV-FPELIPFLQRSMNTREAV-HFE
FK--AQHSNA--PYEVHVYPSE--EGLSVYCQDISERRMFEKERLQMAAGIGHEVRNPMTTIRGFLQLL--GAKEELQCKGYFELMIEELDRANSIISEF
LSLAKNKT----VDLKPLSLNSLIENLFPLIQAGAM---LSDKNIIIELQ---DIEVLYLDEKEIRQLILNLVRNGMEAMPGSGTLTIRTFSDGGEVVLS
VQDEGTGIKAGIIEKVGTPFFTT-KE-----DGTGLGLATCHSIAARHNANIEIDTGE-SGTTFFVRFKSH--------------
>tr|G6GEM7|G6GEM7_9FIRM Multi-sensor signal transduction histidine kinase OX=871968 OS=Desulfitobacterium metallireducens DSM 15288. GN=DesmeDRAFT_0591 PE=4 SV=1
--NILLVDDHPENLMALEAVLSSAEYQVIKATSGEEALKWVLKEEFAVILLDVQMPNLDGFETARLIKKSKDIPIIFITALSASEHVQKGYSSGGIDYIF
KPFEPAVLIKKVKIYLRKAEALARAIYDVSVD---TILAIRRIVNANSA-TKAIFGYQS----S--EI---IGKEASQLIPE------------------
LEQSLAADNTKLLCTIGLP----------------------KKGKPIPIEIS---LGKAILDDYLIVCSIRDITERQEIEKA--RNEQYELLEKLVQERT
LELCASNEKLQ-LSEQ-------LFHKTFEFSPVIQSMKDRLVDVNESWENIYRLEEVENLNPEMFKFIEGNAIM-L-FP------QEELLRNVRI-TYE
TKS-GMIRDL--STEVLKLKGE--RCLLWVVTDITERLHLEKERLEMAAGIAHEIRNPMTTVRGFLQMM--KARPQHENQEYFELMMSELDRANSIITEF
LTLSKNQA----VELKMDDINVLLKTLFPLIQADAF---NHMNDVRMELE---EIPNLMLDQREIRQMILNLARNGIDAMRPGGILSLRTFCVDNEVVLE
VQDQGSGIESDVLEKLGNPFFTT-KE-----NGTGLGLAVCFRIAEKHKARISIKTSS-QGTTFDVHFPT---------------
>tr|G2FNX5|G2FNX5_9FIRM Sensory box protein OX=913865 OS=Desulfosporosinus sp. OT. GN=DOT_1392 PE=4 SV=1
--KILIVDDRRENLLALEAVLKSPDYQLVFASSGEEALKCLLKDDFAVILLDVQMPGMDGFETAKLIRRSQDTPIIFITAIYTMENKLQGYSLGAIDYLS
KPFHPEALKMKIKIHLRKAEALARVIGETSTD---SVITLGCILNVNPA-VTEMFGYGP----E--EL---QGQHVSKLFSGE----------ILSVL--
KDSSIWNKTSKILDTAAVR----------------------KSGAVFFVEVQ---IGVANIEEQIFVWSVRDITERIQLEKE--RKDRYQTLEKLVQERT
CELFQANEKLSE--------------TSLKLTNILESITDAFFSLNHQWQFIFVNEEAEKFWLKSREELIGQSIWDL-YPELLALYQKAMSTKEAV-HFE
IT--GLHTDS--PYEVYVYPSN--EGLSVYYRDISERKMFEKERLQMAAGIGHEVRNPMTTVRGFLQLL--GDKEEFKFNSYFQLMIEELDRANSIITEF
LSLAKNKA----VDLQPLSLNKLIENMFPLIQADAM---LSDKEITIDLK---KTVVLPLDEKEIRQLILNLVRNGLEAMSSGGKMTIRTFMDGENVVLT
VVDEGSGIKTDDLEKIGTPFFTT-KE-----SGTGLGLATCYSIAARHNAEIHIVTGS-SGTTFFVQFKQ---------------
>tr|C6D7E1|C6D7E1_PAESJ Multi-sensor signal transduction histidine kinase OX=324057 OS=Paenibacillus sp. (strain JDR-2). GN= PE=4 SV=1
--NILMVDDRPENLIALEAILASPNYRLYSAHSGEEALRHVLTTDFAVILLDVQMPGMNGFETASLIKRSKHVPIIFITAISAAEHVKHGYSVGAIDYIF
KPYHAETLKMKIQLY--------KVIGETSND---TIVTVGIMQTLNPT-AAKMFGYAP----D--KL---AGRPIDEIVPALS--------SFFHA---
----ETNHGARVIETTALR----------------------KDTIPFPVDVQ---IGRASIVGQLYVCSIRDVTDRKMMEEE--RFRKFDTIPCLIALRS
LKYINVNESLLQEGNE-------VINQSADMLQILDSDDK--------------GAERHNPWQPARN--------------------------VRI-RYM
TKT-GDLRDL--SSEVMQVHGE--DCLLSVVTDISERVFLEKERLEMAAGIVHEIRNPMTTVRGFLQLS--RNNP---SKEYTDIMIEELDRVHNIVTEF
LSVGAQAP----TSRKSKQINTVIETLYPLIQSKAL---TGNHDIALDLG---ECPPIQLDEKEIRQLVLNLVLNGLDAMPSGGRLKIRTYSDTKQVVME
VKDQGGGIKEEFLAKLGTPFFST-KA-----SGTGLGLSVCYGIAARHDAVIKVQTGE-QGTTFFVHFKL---------------
>tr|A9GA39|A9GA39_SORC5 Two-component system sensor histidine kinase/response regulator, hybrid OX=448385 OS=So ce56)). GN= PE=4 SV=1
--RILVADDNADMREYLVHLLTP-RWSVEAASNGRAALAAALARPPDLVVSDVMMPELDGVELLRELRRTSSVPVVLVSARAGEDAVVEGLDTGADDYLV
KPFSPRELLARVRTQIEMARAVEAAER-----ERAQEL--------PRFLDAA----SVVLAES-LDYSTTLAR-VAQL-------AV----PVLADFCV
VD----ALDE--EDG--------TFRRVGVAH------------SDPSLAA------V--------------AEEAKRFAPK----LDGNPPTKVLLEQR
----------SVLVEHFTELMRAIAQNEEHLRVIRTIGAHSCVPLARRGRL----------FG--------TLTFMVVRSERRYSRADLAAAEE------
---LGRRCALAVDNARLYRDAQ--S-AI-------------ALRDEFLSIASHELKTPLTPLALQIQTLMRRAPELSRLPDRLGLVRRQSERLRRLVENL
LDISRISAGRLALELEQVRLSDIVRQVVSRFQEGGE---IAESRVTVSAA--DDA-AGSWDRVRLEQVVENLVSNALKYG-QGNPIEITVASMGSMATLT
IADHGIGIAQEHIGRIFGRFERAVSA--RHYGGLGMGLYITTQVVEALDGSIEVSSVLGEGSTFKVTLPLA--------------
>tr|A0LD39|A0LD39_MAGSM PAS/PAC sensor hybrid histidine kinase OX=156889 OS=Magnetococcus sp. (strain MC-1). GN= PE=4 SV=1
-PKILIVDDRPANSMALRVSLSKLDVQIIEAPSGNDALGLMVEHDFALMLLDVNMPGMDGYEVAKIARQTKDIPIIFMTAIHDDAHRATGYQLGAADYID
KPVDTTILLSKVKVFVDRQKLLERGVEEQL--RMTQ-FALGDM-----VFLISPQGKIVYVNEKACQKLQ---------YEKEQLLQLSIEQIGCGHI--
------------E--TSWKEHWL-------KLKSYQTLTFQSHLRTKN----------------------SIQFPVEI---------QSNYVKT----SS
HEY-------NY--AFIRDITDRVHEERLLLSRAVEYGPASIVITDAEGHIQYVNPKFEKITGYGAEEVIGKP--SLLKSPAIYALWDSISRGHEWRGEL
INKKDGSLYWEMISPVLSKTSGKITHFVGIKEDITSLKETEAAKSEFLATMSHEIRTPMNAILGMTELLGETQLSI-EQRGFLSVCRSAGENLLQIINDI
LDISKVESGGLELQHVPFNLRRIVYDAGEVIRFRSH-----EKGLHFIDE--SVPEWLLGDPARIRQILINFLGNAIKFT-EAGTIATVVSTTGSQIVFR
VIDTGIGIPESKQSVVFDAFKQLDSSTQRRYGGTGLGLTISKKLADLMGGQLGLKSQEGHGSTFTLSLRL---------------
>tr|Q2FQ60|Q2FQ60_METHJ Multi-sensor signal transduction histidine kinase OX=323259 OS=Methanospirillum hungatei (strain JF-1 / DSM 864). GN= PE=4 SV=1
--TVLLVDDESIVLDATKAYLTSYGFLVDTACSGKEALACIAEKRYDAVILDYELEGMSGLELMQAIREQYDGPIIIFTGRGREEVVIRAYDLGADGYVQ
KGGDIAELVHRAKDAVAEYQLYEHAP-------------IAYFSLSPGGIITRCNKKARELTGSYFPD---LAGIPGAACEHQEIGEEFCILLPDGAQIT
VSVSVSVARRHHAEQHRFLERLIETIPGPVFFKDKNGRYTGCN-AAFESYI-------GLSKEIVDLW----PAPLAVIYDKDKELADGSLHDVVFYKAP
DEKGEIVGVILDITTR-KQAERDLYDTHRLIESMIDGIPDMVVQVPDLSIIRF-NRAGYEMLGMREDEVIGRKCYELIGR-SGPCEPCASRAALASKKAE
RYVLSRYFACTA--TPVLDENGEVRLIIELVHDMTDQKYAENALRLLTEVTRHDILNNVNAMQLFLDLVKI--KSDT---AHIGEELDALDRLIARIQAD
IEFTRVYQD---L-----------GSHLPRWQRLAD--------CVAECTIPD-HIQVYADP-LLPKVFVNLVDNSLRHGGAVSRISIAAEEQEEGLLVV
FEDDGVGIAPDEKELIFERGY---------GKNTGFGLFFIQEILGITHIRIKETGTAGQGVRFEMSVPKG--------------
>tr|J0RZM2|J0RZM2_9EURY Multi-sensor signal transduction histidine kinase OX=28892 OS=Methanofollis liminatans DSM 4140. GN=Metli_1069 PE=4 SV=1
--RVLIVDDEPSLGEICQIFLEEGGFSCDTVTSGAEALEQVSTSPYDAIVSDYQMPGMNGIELLKEIRGGMDIPLIIFTGKGREAVVIEALNSGADFYLQ
KGGDPIELAFRTEEALVRTRSIEHSP-------------EEYYWIDCDGFLLDVNEQSEELRHLRVMD---VDSLYGQLKEEHHLRVESVHRKKDGTVYP
VEISLAHHREEAHLSEVMNRAIFETSGEATAVFNEDTTIMMAN-REFERLS-------GYPVELGRSWTEVAEEDRGRLLERQRRIREGVVRAYSAVVDP
GTTLR-IASYLDITER-KQAEEAIRKSEENLRSFMNALPEPALLLGADGIVLAANDAMVETFGRRGGAAVGLSLRDLYPE-AFTVLKLPLERAIREKREV
CSVQGRCINVKI--CPVTDAGGAVGSLAVYGMDVTEQKNTGDALNLLSGITRHDMLNQITVALGSLSLASQ--QIDD---EEVRARIEHAHAAVMNIQKG
LEFAKDYQN---M-----------GMMPPAWQRLDA--------VVAAASVPD-GIEVFADP-MLERVFANLLDNAVRHGEGVTAIGISCHEQDDGAAIV
IEDNGIGVPEGLKERIFESGY---------GRHTGHGLFLVREILDITGISIAEIGEEGKGARFVITAPPG--------------
>tr|Q2FT10|Q2FT10_METHJ PAS/PAC sensor hybrid histidine kinase OX=323259 OS=Methanospirillum hungatei (strain JF-1 / DSM 864). GN= PE=4 SV=1
--SILYVDDDTDYHIIVSKFFKRADLSVTFCSTAHAALDLLEHELFDVIVSDYLMPVMDGISLLKEVRKRGRLPFILFTGRGREEVVIQAINNGVDYYLQ
KGGDFTDLIHAIENLERRFRTLDRIH-------------MVAFHLDENGIVQYCNDYLDEFLHKDFFE---MAVPPDEAVSKESIHEEMKILLRSGEIRD
LDIINTDMRNEALSWKQRYEKLTARTGQIAYEYDIDNDILLMD-ESAGHVI-------GYAPELGELWMNIHPDDYQNVFDFSRAVKNGRIQIQGFFDPP
DTRSKIIGIISDITRE-KEAEIALLKSEEKFKLYLEKAPYLVVIFDRYGRISYTNPAGEQLTGYSSAEITQMSVFDLIPE-EVPETRIVFETLFERGYNV
TLINKNIVYVEA--DAILLEGGEV---LGFCLDITENVVNEKKLRLLQSITRHDVMNVVTSIRGYMLLLND--FEDP---AERERIFDTIIGFLKRIENL
VNFSREYEQ---I-----------GVHSPTWQNVAH--------LIVRCAIPQ-DLALYADP-MLDHVFANLYHNSVNHGGDVTEISCYMGIDEQGIRII
WEDNGVGIPSEEKDRIFILGY---------GKNSGFGLYFISEVLAMTGISITETGEYGKGARFEISVPRA--------------
>tr|D6SMK4|D6SMK4_9DELT Multi-sensor hybrid histidine kinase OX=555779 OS=Desulfonatronospira thiodismutans ASO3-1. GN=Dthio_PD3355 PE=4 SV=1
-NTILVVDDTQTIRHITKKTLEADNYVVLAASNGPEALSIAADKIPDLILLDVMMPDMDGFEVCSRLKATRDIPVVFITASGNKEHEVKGLDLGAEDFVH
KPFHEGVLLARVGQILRRLQA------EEQLRTSR-E----SHRML--------------LDSIETQVWHLTDEHTYGAVNRAH-------ADFFGFSPS
-EIANRDIDQ------FLPEGMVAAI-----R--------KGNREVFSRKE---QIH------IEEWVSNASGERLLSIT----------KTPKIDEQGN
VDYVVCSA--EDMTAQW-KATEKLKVSEEKLSSILNNMKDVVWSISWDLRHLYLSPSSEKLYGISAHEFYENPFKDVTHPEDRHLTKKAVEQLLEEGEAV
IRPDGSIVWINDTSKMIYDDNQQPARVDGVTRDVTELVKARQAKSDFLANMSHEIRTPMNGVIGMTGLLLDTDLDS-EQQHYARTVRSSAESLLTVINDI
LDFSKIEAGRLDIETVDFDLEAMLRDFSGMMAVKAE-----EKGLELICSMDPNVPMVRGDSGRLRQILMNLVGNAVKFT-EHGEVEIRVSKSEVELCFQ
IRDTGIGIPQDKQDSLFESFSQVDASTTRKFGGTGLGLAISRQLAEMMGGTAGLESVEDQGSTFWFTVRL---------------
>tr|K9UJS5|K9UJS5_9CHRO PAS domain S-box OX=1173020 OS=Chamaesiphon minutus PCC 6605. GN=Cha6605_3939 PE=4 SV=1
--TILLADDNADVRDYVRRLLSR-SYQVETVADGVAAMESIYRQQPDLVLTDVMMPRMDGCELLRVLRSTAEIPIVLLSARAGEEARIEGLATGADDYLI
KPFSARELVARVEAQLRRTERDETDIAEANL--------DRIVSSLRDGFATFDRQWRYVLGQYSWNVFPHQVGVLNRAMTEQVEAQFEFYYSL------
VDA-------WVE-----HRVYPTSDGLAILMADISDRKRAEQKRLLELADCLALGVRACILPFPYLITPEQNTPINELLGTAIAVAHGCHSAPIVGADD
LPLGSLGTNIASIVFDRERASLALQTSEAKYRMLFESMDRGFMLFDEHGVPVEVNSIFGSLTGLEGSVIERKQAEESLRHDQIFGYESAVDEKFQQTIST
AHADGGIHWIWVRSSVYCNADERPTRLLGMVMDATDRKQAEATLDSFVYIVSHDLKAPLRAISGWIEEDFDGSLTAH-TTEQMNMLRSRVHRMEGMIDGL
LQYARASRKDSQ--LELVCVADLLAEVIESIDPP--------SIFTV--SIATEMPTLEAKRLLLFQVFANLISNAFKHHRSDGCIRISCRAQSDFYEFA
VADDGPGIDPVYHDRIFIIFQAA-NP-QKNSDSTGVGLSIVKKIVETAGGQIWLESELGKGTTFYFTWPRL--------------
>tr|E0UHY9|E0UHY9_CYAP2 Multi-sensor signal transduction histidine kinase OX=497965 OS=Cyanothece sp. (strain PCC 7822). GN= PE=4 SV=1
--RIILADDNADMREYVKRLLNK-LYQVEAVGDGMAALEAIRRHPPDLVLTDVMMPQLNGFELLQQLRSTQELPIILLSARAGEEYLVEALEAGADDYLV
KPFSARELLVRIEAQLRQTQKEQAETARQQT--------IDILERITEGFVAFDSQWRFLLGNNIWELFPQAINHLQQAINEQVSLTFETFYAR------
LSR-------WFL-----LDVYPASEGVSVYFRDITESKNQENEARLR------IALKSAPIALKYTWIYN---QISEVIGK----DEGAENAQALS---
------DSGVG----QRKEVKINWQDQEIYFDLTLEPLKN------------------GQIIGLTGASIELKYIEQVWLN---FTGRTSCLQTYLSAFEQ
IRADGEYRWVFDRGKPLFTPEGIFAGYIGSCVDITEQKEANLMLDQFAYVVSHDLKAPLRAIAQWIQEDLEDVLPQE-NQAQLELLRQRVYRMNNLIDSL
LEYSRIGRTEET--IEDVNVKNLLDDIIDSLSPP--------PSFTI--NVASSMPTVTTQKVLLSQVLTNLISNGIKHHRLDGKLEISVQEQKNFYQFF
VSDDGQGIPAQYQQKIFAIFQTV-KT-RETKESTGIGLSIVKKIVEIQGGNIILASQEGQGSTFSFTWPKN--------------
>tr|L0IAE8|L0IAE8_9EURY PAS domain S-box OX=797302 OS=Halovivax ruber XH-70. GN=Halru_0583 PE=4 SV=1
--ISLSIVDDTAVASEVETAL-RADLHVSVETDPNDVLDALESTAVDCVVTGYDLPGTTGVELVSHVRAIAELPVILVTDAGSEAIASEAISAGVTDYLS
KQETARTVVKRIRDAVDRRRDRERHLTIETATEGISHLDEGRFLYVNEAYRADLLGESWERLEVREEILPEVYADGSTF-VEDHNLALTADGTLVCTVHD
V--DARDARAEIEER-LFVDRATDLLSDVLYVVDYEPSAIDESVQEFFEAALDAVLAGDS-----VVV------------ETAIETAADEPFEDQLRDGD
GTLVGV------IG-VGRDISAARERKLRA----LNETGQELMGGETQAAVAEIGVEAARDVGANAIHLYDEETGPVA-----QTESGLLPDPPTLEPGS
SIADPSIESIAADEDVLGEILA--GSILEAVERTEQLAARQRQREEFASVVSHDLRNPLQVASGQVELARETADSD-----ALGEAIAALDRMDALIDDL
LTLSRQG--ETIGSLEPVVLDHLARQCWGTVDT---------PAATIRCDS---DLVVRADRSRLRQLLENLLHNAVEHGDA--SLTVTVGATED--GFF
VADDGRGIPPDDRDRIFETGYTTSS------DGTGFGMGIVRQVVDAHGWSIEVTESAGGGARFDVT------------------
>tr|L0JH90|L0JH90_9EURY PAS domain S-box OX=797303 OS=Natrinema pellirubrum DSM 15624. GN=Natpe_0289 PE=4 SV=1
--TVCYVDPEPTATEVPTA-LERDRLVVESVASEDAALARLESAAVDCLVCRAAGDDIGDDTLLASARAEPTLPIFLVVDAFDEADASAALEAGATGCVS
AEHGTRRIERAVDAATERRDAAAARFRTENASFAVITAGDGTIRYANDAVADDLVGDRISTLNSHRDTIAHYLADGHEVPVGVSFGEAAVSGLFTAVIRD
L--SDRRRLEERE-------ATLERIGDAFVSIDRPREELLGSLTAFEDHAFATTVSFTQ-------Y------------FAALER----WFE-VRAYPS
AD---G------LS-VFTDVTDRAEEELEASITALQALYDISTRADADEKVPELLELGCESLGLSHALLQAGESCPLA-----EAYCRKTIKTHELVTVA
NAPLGELGSVTVCFASEPREAE--RTLVKLMAKWTERQQSHETRQEFTSVVSHDLRNPLNVAQGSLDLALE-GDDT-----ALEACEEALERMEQLIDEL
LSLAEQG--ATTADLEPVALRDLATKAWSMVDT---------GDATLAFDG---AGRIRADPERLQQLLENLFRNALDHGSA--DLTVTVGDREG--GFY
VADTGRGIPVEERESVFDIGFTTAE------EGTGFGLGIVKRVADAHDWGLAVTEGDAGGARFEIT------------------
>tr|E4NRL8|E4NRL8_HALBP PAS domain S-box OX=469382 OS=10706 / PR3). GN= PE=4 SV=1
--TVLCVDDEPGSADLTAAYLERDRLTVTTATSVQGGLNALTETDFDCIVSDYDMPGLDGLAFLEAVRVDPKLPFILFTGKGSEAVASEAISAGVSDYVQ
KESGTDALARRIHNAVERFRKHAAKVQENSPDAIVVSVGD--FVFANTSAADDLLGRNLLSLEAVKAVIAH-A-DGMTFSAEMTVRAITWNGGHVAILRD
V--TNQEEQDERER----YAAAFSRAMDAIIVADLPREELLGNLSEFTDDMWAQSLGENH-------G------------VLSLIRPDGEYAA-TRDVVP
GE---H------LS-VLRDVTGRLERQRQADHEALERMYRITADREAEEKVSALLELGADYLDVPHELLQPGETGPLS-----KAYCRKTVIEDELVSVQ
NSEEDELGCVIVCFAGASRKGE--EAFVELLARWQEHRRNNREREEFASMVTHDLRNPLSVASGYLELAREDGDPE-----QFDRIEDALSRMERIIGDL
LYLAREN--EQIRETEPVELESAVERAWQTVDT---------HEATLSVDG---DGTIEADQNRLCQLLENLFRNAIDH-GT--DVRVRVGSLDD--GFY
VEDDGPGIPESERDNVFEQGYTTRN------DGTGFGLSIVTEIVEGHGWSIAVTEGELGGARFEIS------------------
>tr|G4IIB0|G4IIB0_9EURY Multi-sensor signal transduction histidine kinase OX=751944 OS=Halobacterium sp. DL1. GN=HalDL1DRAFT_2799 PE=4 SV=1
--RVLHVDDEPDFADLAAEFLERDCLEVLTATSPKDALDRLREERVDCVVSDYDMPGMDGLEFLDELRDRPDLPFVLFTGKGSEEVASDAISAGATDYLQ
KERGTDLLANRVRNAVEQHE-SRTSYREKAADAIFLHDPEGAVNDVNSRARSALLEMDVTEFAEAQERVRRAMKDGAEFWVEVHLKRTVINGQVLAMTRD
V--SERKEGEKLAE----SEQRYRTLAEAVAMYDPPADVLEGRISEVYEPVFRTTIEDGE-------I------------GSTTIGADGRWTA-PLRDGD
GDVFAG------LS-FAQDVTEERERRLQEQQEKVKALHDVAADIEADEVYNLLVTAGEDVLDFDEEEYHGAVPVDAE-----DSFAAKSYRTGESILAE
DLSAA----ITVQAVAET--TD--LELTELLVKHRDLRTYAAEREEFASVVSHDLRSPLNVASGRVELARETTDSE-----GLQIASDALDRMDEIVERT
LELAREG--RTVGETEPVRLAEVAEQSWQVVET---------ESAELRVED---DVAVEADPERVQHLLENLFRNSVEHGAD--SVTVRVGALDG--GFY
VADDGPGIPPEERDSVFDPGYTTAD------DGTGFGLAIVAEIVEAHRGEITVTEDVASGTRFEIT------------------
>tr|Q3ILY8|Q3ILY8_NATPD Receiver/sensor box histidine kinase OX=348780 OS=Natronomonas pharaonis (strain DSM 2160 / ATCC 35678). GN= PE=4 SV=1
--HVLLVDDAVASSETMAAFLEQGDFSVELAATGTEGLRRLHDEDYDCVVSDYQIPGMDGLELLAAVREEPKLPFLLLTDYGNESIASEAISAGVTDYVK
KRSSTKVLMNRITNAVTKHRERERVLTLDSINDIFYIANAGTLRYWNDQLNDEIADMRIHDFSVPEPRLELPPTAGGEQ-VPHECTVTPLADGVVGVARN
L--VERKEREELRTLKERFELATEGANLGVWDWDHEPAEILDWRRRVHQAALRDHIEGGTE----YYT------------ELRMQTAGGDWIRVVERDAD
GTPVRA------VG-IHLDIDDRTEQALREKRDIFTQGPTVVFRWENDGTISYVSKNVEDVFGYSVADLESQPFRPL----------VHYEDVERVVSKT
KTANGRIIT-AEHTTLWAGDDV--SHRLGYLIDITERKERQQRQDEFASVVSHDLRNPMNVAEGRVELAQMACDND-----HLSDAGDAFDRMHALVDDL
LTLARQG--DTITEPGPVDLSALVSACWCSVDT---------ADAELEADT---PTVVLADRSRLKQLIENLFRNAVEHGGR--DVTVTVGELDDRNGFY
IADDGPGIPDDKREDVFEHGYSTAD------SGTGFGLAIVREIAEAHEWSLNVTESDGGGARIELA------------------
>tr|I7BPE7|I7BPE7_NATSJ PAS sensor protein OX=406552 OS=Natrinema sp. (strain J7-2). GN= PE=4 SV=1
--RVLHVDADPAWTTAVADCLERVPIETLSVDSASDALERLEHADIDCLVSEYDLPDTDGLSLFDAVRATDALPFVLCPRAGSEAVASEAIGAGVTDYVP
KGEGA-TLRDRLVEAVSTIRRRERQLCVETAREGISLLDAGRFIYVNQAYPSTLIGEHWERLTVREEIIPTVLADGTTF-VEAHSLSMTGNGDLICTVRD
V--TDREERKNLER----YETIIDALGDPVYTVDYEKDDIVGHISFLLEDCVRSLLSDDTDA-RQRTY------------EITVETSDGERCESLLPLAD
GRYRGV------AG-VVRDITEARERELERYETILETLPDEVYSLDAAGVITEIIPPINDDVGHRPEELVGEHVS-------------VIMDADDIDTAE
SEIDDEMETIAKNHIALPPDED--GRFVGVLRNIADRKARERERDRFAGIVSHDLRNPLNVAQGHLERVREACDDD-----DLEAIAWAHDRMAVLIENL
LTIARER--DPDPDTEPVDLAALTADCWRHVET---------DDATVAIET---DAVVRADRARLAQLLENLVSNAVEHGTA--AITLTVGDLDD--GFF
VADDGPGIPAAERDKIFESGYSSDG------AGTGLGLAIVERIADAHGWTVTVTEGDDGGARFELT------------------
>tr|L0JP88|L0JP88_9EURY PAS domain S-box OX=797303 OS=Natrinema pellirubrum DSM 15624. GN=Natpe_2599 PE=4 SV=1
--RVLCVDDEPQWAVKIAELLDRVAIDTLSATSASEALEYLADREIDCIVSEYDLPDADGLALLEDARSEDSIPFLLVTDSGSEAIASEAISAGVTDYVR
KADDPEALADAVVDAVEAAQERERHLHVETAQEGVSILDSGRFVYVNRAYPAELIGEHWELITAHEEIIPTVMADGTTF-VEAHSLSTTGNGDLICTVRD
I--TDRKEREDLER----YETIIEALGDPVYTVGYEKDEIVGPISFLLEATVGSLLSADTEG-RQCTY------------EITVETSDGERCESLLPLAD
GQYRGV------AG-VVRDITAERKRELEEYETIVETIPDEVYTLDAAGRVTKIVPPSNDELGYSPAELVGEHVS-------------LFMDEADIATGE
AEIDPEMETITRNHIALPPDED--GRFVGVLRDITDRKERERERERFASIVSHDLRNPLNVAQGRLAEARRTCDET-----HLEEVAWAHDRMGVLIENI
LTIARDR--DPQPDPEPIDLAAIVDDCWDHVDT---------GTAALRVDT---DAVVRADRARLKQLLENLLRNAVDHSRS--GVTITVGDLAD--GFY
VADDGPGIPPDERERVFESGYSSDG------DGTGLGLAIVERIAAAHGWTATATESAAGGARFELA------------------
>tr|Q5V5P7|Q5V5P7_HALMA HTR-like protein OX=272569 OS=B-1809) (Halobacterium marismortui). GN= PE=1 SV=1
--RVLYVGTDSDDTETLSTALERNRFTVETARTVDEAMARLAAEPVDCLVSDYRLSNGNGIELLETVRDEPALPFIIYTAQGSEAVASEAISAGVTDYLR
KEPGAKGLANRISDAVDHSRERNRALQVNSMQEAACIYDADRFEIVNETIRNELEGQTSRLVDCYQELLDGTRGHGHAV-VAYQLTPLVVDGGIVGVARD
V--TEQKEREELLR----NKRAIDEAPVGVTITDYSLPELLGNCRILQVDALRDAIDAGEQ----VSV------------ELRNYRKDGTWNRAPVRDDD
GTVVNY------VG-FQQDTTERREKRLEETSSLFENSPDMIDVLDADGTICEVNQRFCAELGYDESEVLGRSIWEF----------DLMFDAEDVQTQL
SGFDEGLYE-RRVHLLFNLEGE--DRFLAISRDITERKEREQEQEQFASVVSHDLRNPLTVARGQLELLREESDSE-----HIDAIDTAHQRMDTLIDDL
LTLARDG--ASPASPVVVDLEQFVQTCWQNVDT---------KAATLRTDI---DRPIRADESRLRQLFENLVRNAVEHGGD--DVSVTVGELAD--GFY
VEDNGAGIPEPERGDVFSAGYSTAV------EGTGFGLSIVKQVADAHGWTVRVVSGADGGARFEFT------------------
>tr|G0HVV3|G0HVV3_HALHT HTR-like protein OX=634497 OS=102182 / NCIMB 2187 / VKM B-1755). GN= PE=4 SV=1
--QVLYVGTDSDDAETLSTALERGRFTVETVRTAPEAVARLADDTVDCLVSDYDLPERNGVELLETVRDEPALPFIIYTARGSEAVASEAISAGVTDYLR
KEPGTEELTNRIFDAVEHHRERNRALRVNSMQEAACIYDAGRFEIVNETIRAALEGQTSRLVDRYQELLDGTRGHGHAV-VAYQLTPLVVDGGIVGVARD
V--TDRKEREKLLR----NKRAIDEAPVGVVITDYSLPELLGNCRMLQVATMRDAIDAEER----VTV------------ELRNYRKNGTWNRAPVRDDD
GAVVNY------VG-FQQDITERREKRLEETSSLFENSPDMIDVLDADGTIRDVNQRFCAELGYDESEVLGRSIWEF----------DLTFDAEDVQTQL
SGFNEGLYE-RRVHLLLSLDGE--DRFLAISRDLTERKEREQEQEQFASVVSHDLRNPLTVARGRLELLREESDSE-----HIDAIDGAHQRMDTLIDDL
LTLARDG--TSPASPVVVDLEPFVQTCWQNVDT---------KAATLRTDI---DRPIRADESRLRQLFENLVRNAVEHGGD--GVTVTVGELAD--GFY
VADDGPGIPVADRGDVFDAGYSTAV------EGTGFGLSIVKQVADAHSWAVRVGSGSDGGARFEFT------------------
>tr|Q5UZG8|Q5UZG8_HALMA Adaptive-response sensory-kinase OX=272569 OS=B-1809) (Halobacterium marismortui). GN= PE=4 SV=1
--YVLHVDDDPAVVEAATGALKQCGITVETETNVADGLKRLDEGTFDCVIAGYDLPGQTGVEFLDAVRKQPDMPFVLFTTEGNEAAASDAISAGVTEYLR
ADGGAERLAHTVVNAVERTARRERAIEHSTARAFMRATTAAVAQVTVDAAANAVHFADGDGLNQVEELIPPVFGDGLAW-------QAFETGRVHNDVAS
S--PDRYNPDDIQ-----SELILPLGDHGVLLIGFDDTDVLATL----------------------------------------------SVH-------
----------------ATAALNDRDRQLREERDALNTLYDLFYVIGTDGSLQRWNERIPEVTGYSDDEIDEMSVS-------------EFFPADEHETVA
AAV-KTVEALTAFAGTLTDADG--APVVGIGRDISQRKAYEQQRDEFTSIVSHDLRNPLTVAEGNLELARAEYDSD-----ALDKVSRAHERMRALIDDL
LAFARAG--ETATDLESVALTGIVEECWQSVES---------DQATLVVEG---DRQVQADTAKLRRLLANLLRNSVEHGDN--DATVRVGVIKDRNGFY
VADDGPGIPEDDREQVFEEGYSTGE------NGTGFGLKIVQRLAEVHGWTVTATESEAGGARFEVT------------------
>tr|E1RHG2|E1RHG2_METP4 Multi-sensor signal transduction histidine kinase OX=679926 OS=Methanoplanus petrolearius (strain DSM 11571 / OCM 486 / SEBR 4847). GN= PE=4 SV=1
MISALYVDDEELLLVVAKEYLERGGFRIDTAKSVNEALMMIEGNSYDAIISDYQMPGKDGIEFLSEIRGANTIPFILFTGKGREDVVIQAINNGADFYIQ
KGGDPRELVYKLKIAVDRKR-KNRELREINSKLRLQQ----IITFLPDPTFAIDNEGRIIAWNSAMEVLSGAK--AEDVMGRPILIDLVINPDIFGVEKS
KWFTSSPLYGAIEDITHIKLNSL-SELDG--INACGILEEFKNPGSFFDTGSRIVYILKTSIELATQARSRMKRMREMTNSSLQK-YTGYRDEELIHGTI
GGNKVILGVSRNISA-LKEAHDSTLESERRMRAVFDQSFQLAGILDRKGRLLNVNRTAMKYVEGEPDDYIGKY---IWNTEWTERLDLQMAAGGVTVKSQ
TDRDGFLRLLDFSIRPVRDENGEIIYLVPEAADITRRKKAEDALILLNSITRHDILNRVTPVLGFLEIVKDNASDP-DQSEILEKLKSQVKDIENLIKFT
GLYDKLGASE----PSWQNPSRILNSLKA---P---------KEIAIKNSL--PAIEVYADP-MFEKVFSNLLGNSLMHGKRVSEISVSCRRTDEGISIF
WKDNGCGIPECNKEKIFLRGFGD---------NSGLGLFLSKEILSITNIRIQECGKEGEGAVFEIIIPPD--------------
>tr|A3CV69|A3CV69_METMJ Multi-sensor signal transduction histidine kinase OX=368407 OS=Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1). GN= PE=4 SV=1
MYRILVVDDEPGLLEQNRIYLETSGMRVETTSSSLQALDMLSKAPYDAIIADYEMPEMDGITLLKEVRNRLSIPFIIFSGRGREEVIIEALNNGADFYLQ
KGGNPSELQNMILQAVRRKQ-AEEEVQRAGDL--YRS----VFEHTGSATIIIEGDMTISLANNEFEHLTGYS--REEIESKAEDVERLRNYHLHGSQKD
LHMTIGIIPRSVADVTDRKQESLEAQCRE--MEDYQATIIWEELTGVKKNRIQEVRITSGAIELRDITSKRIQHRIDIFRFSADL-TRVEDTHEWQITWS
DEDVTLLELFADLFS-RIRVQERLRTSEERFRSLVERSHDCYIRATTAPQAIYISPSCESLIGYTREEILGNPNFRLIHPEDRKT---FLQERDATQPYV
RRKDERYIWVEACTIPVYGNDGRAVAIDYAIHDIDAWKQTEAALILMNSIVRHDILNQVTVVLGHIALLREQPLDP-TVADALGKQQAAVEIIQSQIGFT
RDYQDLGVRA----PRWFPVEPLVTGASKALRP---------IGIRISTDL--DGLSVYADP-LLSSVFFNLLENAGRHGKTVTEIRVTAMPDGGGARIV
WEDNGVGVPREHKERIFERGFGS---------HTGLGLFLVKEVLSITGIAIRETGEPGKGARFEIVVPEG--------------
>tr|I7KDP8|I7KDP8_METBM Signal transduction histidine-protein kinase atoS OX=1201294 OS=MS2) (Methanogenium bourgense). GN= PE=4 SV=1
MFRVLVVDDEPALLELTQAWLARSGMQVETTTSPTQGLDMLAKTRYDAIVSDYEMPEMDGIAFLKEVRRRMAIPFIVFSGRGREDVVIDALNSGADFYLR
KGGDPSELRNMILQAVARKQ-AEADVQLAGDM--YQS----IFEHTGAATIIIESDMTVSLVNSGFTDLTGYR--REEVEGKDRDLERLSGYHLHGTPRD
VYMTVGLIPRSVADVSDRKQESLAAQCCE--MENYQATTIWEEVTGIRKSQIREIHIPSGAIELRDVTLKRIRHRIDIFRFSNDR-ALMDNTHEWQMSWS
RDDVTLLTLLADLLV-RIHGHKRLRESEERFRTLVERSHDCYVRATKLPPAIYVSPSWEHPTGYTREEFMGDPGLRSVHPGDREI---FMQEPGADRVYA
LRKDQRYVWVEVCTIPVYGDDGRLVAVEYAIHDIDAWKQAEAALILMNSIVRHDILNQVTVVLGYIALLRDQPLDP-VVAEALDKQQAAAEIIQSQIEFT
RDYQDLGVRS----PRWFLVEPLVTAAARALRP---------AGIRIVNEL--DGVSIYADP-LLSSVFYNLLENAMRHGKTVTEIRVTAVSEDDGVRIV
WEDNGVGIPPEHKDQIFERGFGS---------HTGLGLFLVKEILSITGITIRETGIPGEGARFEIVAPEN--------------
>tr|A7IAW9|A7IAW9_METB6 Multi-sensor signal transduction histidine kinase OX=456442 OS=Methanoregula boonei (strain 6A8). GN= PE=4 SV=1
MISVLYVDDEATLLELTRLFLEYRGFSVDTKQSVQEGLDALKVRQYDAVISDFQMPGIDGLEFLRNVRTTGDLPFILFTGKGREDVAIQAIDDGVDFYLR
KGEDARRLENRIKLAIER-R-TPRNVPASPGIL-VAE----LINFFPDATFAIDKEGTLIGWNHAMETLTGVP--APEILGKPSLVDLIFRSDIIPRLSK
LSCRAMPLRGAIEDPRHAGVYQYCSRPSG--ENEVHFLDFFDDRERFTSATD----IWAGIFLISA--RKKVQEYEEFANSAAARIFETPDSASLFIVLY
EGKIAHFLSLRDTTG-SRTLEGALKEGDEEFRLLFDEPVALCEIVYSGGRILKANDAVWRTLGASRSSVIGKTSREAYNTPEPPHLDIY-AATGKTETFE
PELQKHFRVSVCS--PGKDRFATIFY------DITEHKKAETALLLMASITRHDILNNVSALLGYVTILRMKFQNP-ALSYYFTKLEDITTAIQHLISDT
QMYQNFGIAE----PKWLEVSTLIRHLQI---P---------ETIVLTVDL--ADVELYADP-LLEKVFFNLLDNSIRHGQTVTEIRVSSRHNDDRLVLS
WEDNGVGIPSEEKSKIFEKGFGK---------NTGLGLFLCREILSITNISIQETGEPGRGARFEITVPPG--------------
>tr|J1AT88|J1AT88_9EURY Multi-sensor signal transduction histidine kinase OX=28892 OS=Methanofollis liminatans DSM 4140. GN=Metli_2375 PE=4 SV=1
MISVLLVDDDPMILDVTSLYLQRGGFSVKTCEDASDALGVLEGRSFDAIISDYEMPEMDGIAFLKVVRARETAPFIIFTGRGREDVVIEALNNGANFYLQ
KGGDPKELKNMIRQAVQNTR-AEAALRMSEAR--YRA----VVESQTELISRFRPDGTQVFANEAFCRYYGMT--PEKIVGKEEEIPIIQEHFVNGEVRR
AIFNEGSAPQSVGDTTDRKIYIL--------------RAIFEELAGMPLLRINEVYEFRVLVGVLDISRKGLTEKVNLTGRSRDE-IVGREIHDF--ALF
DSGGAVAGVIVDIGE-RKRMEQALRESEMKYRTIADFTYDWEAWLGPGGRYFYVSPSCERITGYSAGEFMDDPTLRIAHPEDREAVERYLHDNEGVGHIE
VTKQGEVRWISHYCQPVFREDGTYMGRRENKRDVTERKHAEETLKLLSNITRHDVLNRLTALLGYLEFVRDFGLEP-EAVALVEKAEESANVIRHQISFT
RDYQDIGVHN----PAWQDVRRLVRDASMTLYR---------SEIAVENGI--GGVLVYADP-LLEKVFTNLIDNAVRHGGTVNRIGFSVREEGDSLIIV
CEDDGAGVEEEEKRKIFRRGVGK---------NTGYGLFLAREILAITGLSIREVGTPGQGARFEIVAPCG--------------
>tr|B8GKS7|B8GKS7_METPE Multi-sensor signal transduction histidine kinase OX=521011 OS=Methanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c). GN= PE=4 SV=1
MIAILYVDDEPSLLEVGRIFLERYKFTITTALNAPEAIQMLEQENFDAIISDYQMPGMNGIEFLIEVRTRGSIPFILFTGRGREEVVIQAINNGADHYLQ
KGGEPVELGHKVRLAVQQRR-AEASIRDHERR--EAD----ILNFLPDPTFAIDTRGVVIAWNRAMEKMTGVS--AAEMLGKPGLIDLILHDDINGKRAK
IWFTAAPLYGAIEDVTEIKLDELSRQEQA--LRESDREDLITRLTGVITAILSDLHLAGNIFMQFIYDEVVFIEQALKYGFDRDE-YLAHRVPRILMTSF
ISRLSYSNLARTVKE-RDDLLGYLHKSEDKFRTLVENIPQKIFIKDRDYRYVSSNEKFAQDFGIHADEIVGRSDTDLFSPEFAAKYHADVMETGQTEEFE
-RLEGRDIWIHTIKTVVRDKNGEITGVLGAFWDITERKRAEEALHLLSSLTRHDITNQLTVLMGYLAILRMELFDP-GLDDAFLKISTTLQRISTMILFT
REYEAIGVMA----PVWQNIHSLVDTAAVQTPF---------GQVELKNDLP-ADLEVFADP-LVVKVFYNLVDNSVRYGGKITIIRFSVQELGDDLVVV
CEDDGEGIVPEEKEMIFEHGFGK---------NTGLGLSLSKEILDITGITIRETGEPGEGARFEMIVPRG--------------
>tr|E1RD16|E1RD16_METP4 Multi-sensor signal transduction histidine kinase OX=679926 OS=Methanoplanus petrolearius (strain DSM 11571 / OCM 486 / SEBR 4847). GN= PE=4 SV=1
GISLLYVDDEPVLLNMSKLFLEKIGFSVTTAGNAKDALKLLSEKPFDAVVSDYQMSGMDGIGLLKSLRSSNRIPFIIFTGKSREEVVIEALNEGADFYLQ
KGGDPKELAHKIKSAVKSRR-SEEALE--KRV--IML----TQPP---NIEFEDDEIQRIQDDPDGTPITKPSNLCSDVIRK-----------IEN---E
AYYEVPSMSKALF--LRQAYDELVKSEKE--LRESEA-TLV-----------E-----AGTANMDY-I-----------------------VGYKWIKIL
FNDS----FIWDVTG-QKEIEEQLKESENKFT---MNSPF--TLIS----FTDVNEKFVNQ-GYSVEETIGK-TPG-----DNNE-KALIRER--IDNYE
RKKNGEINLCCFTSRFIRMGG--F--CLAVVEDITERKTAEEAVRILSDITRHDILNQLMVIKGFLEIAEDHVLDQ-PGADCLNYIKKASSAIQRHIEFT
REYENLGVNK----PVWMDIRELISDS----GN---------EKVVLY-DC--RNIEVNADP-MLEKVFLNLMDNTIRHGEA-TEVRVGCEI-GDLLKIL
WEDNGTGIPDSDKERIFEKGFGK---------TTGFGLFLSREILSITGISICETGEEGVGARFEINVPGE--------------
>tr|B8GIM6|B8GIM6_METPE Multi-sensor signal transduction histidine kinase OX=521011 OS=Methanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c). GN= PE=4 SV=1
MITVLLIDDEPAILDVTRLFLERTGFCVETTSSGSEALEKFDSTNYDVIISDYEMPGMNGIELLRALKSRVDVPFIIFTGKGREVVAVEALTYGATYYLQ
KGGEPRVLESLIEQAVQKKR-AEEETRLSNLR--LAD----IVNFLPDPTFAINCEGIVIAWNRAIEEMTGVK--AMEIIGKPGLIGLLNATPLRGNPSV
LWAKATPLCGAIEDVT--------RQELQ--MDALQQVDLFSDATGVASIITHSITMAAIWQIQVLI-EGYLLDYADQIGANRDK-FAETGVPQMVEARQ
ISALALKNQSRMLAE-RMKAEDDLKESREQLRSLIEFLPEAMLQYDLDGRMITVNKKAVEMSGSLEDEMIGVDVLSFFAPTDRDLIRENTLTEGTSPITE
LKKDDTTIPSEFSFSLLRNRNDSPTSFIGLGRDITKRKMVEEEIRLLSSVTRHDVLNQLTALRGFLEMAEEAPDTL-SKGQLIRKVMETADRIHHQITFT
GDYQEIGLES----PQWQNLDTTIRRAASALDL---------QEINLAIEVN-TS-SLYADP-LLEKVFFNLMENAKRYATGMSSIRFSIEEKDSDPVVI
CTDNGPGIPPAEKERIFTAGYGK---------NTGYGLFLITEILSITGLSIAETGTAGSGARFEIRVPPD--------------
>tr|A7IA63|A7IA63_METB6 Multi-sensor signal transduction histidine kinase OX=456442 OS=Methanoregula boonei (strain 6A8). GN= PE=4 SV=1
VIHVLSIDDEPALLDLTRLFLENTGFAVTSAVSAEEALEILKTRRYDAIVSDYQMPGMNGITLLQHIRGADTTPVIIFTGRGREEVVIEAINSGADSYLQ
KGGNPKELAEKLRQIVRRSR-AEGALRKAEAR--YRA----LFQN---IIRILDHQGRIAYDSPSAAKILGYA--PGSLEGR-----------IDG---W
VESIASNLIGVVV--TERKYNELAASEQRRMVRASET-NII-----------P-----GKRLDIFP-Q-----------------------LNAKWVPLK
DHEG----VVQDITA-RKRAERELHESEEKYR---EAKND--LLAD----IIDLNQAAEDL-GYSRSEMLGM-TLL-----EPEK-KEVRVPR--LRYH-
RKKDGADIALAW----FSFKE--V--LILSIRDLTGVQQIGDALRLLIGVTRHDVLNSLTLLNGFLR---DREVDD-PTRDLLEKQEKALLAIRSQIEFT
RTYDDLGIKA----PVWQHVGNTAVRAYAQF-I---------HTISFT-ET--GDLEIYADP-MLEKVFYNLFDNAFRYGEGVTRIRLYGEV-GTDLLLF
FEDNGIGIADSQKSRIFSRGIGK---------NTGLGLFLTREILAITRIGIAETGEYRKGARFALRVPRG--------------
>tr|A7I8F9|A7I8F9_METB6 Multi-sensor signal transduction histidine kinase OX=456442 OS=Methanoregula boonei (strain 6A8). GN= PE=4 SV=1
TISVLYVDDESVLCDIGKLYLEQTKFTVTTASSARVALTRLKSNGIQAIVSDYQMPEMDGIEFLKQVRATKHIPFILFTGEGREEIAIEAFENGADAYIQ
KGGDPIDLTHKIKVTFEHRR-ADVQLNVLNRL--YTV----LSAT---IVRIHDNEICRIAVDNAENHLIEPI--------------------LNA---T
FYASEPGFF--------------ITAENN--LKKSEL-QQF-----------F-----GRRLWLEF-L-----------------------LEIKRVVYF
VGEK----NIRDITD-RKVVQDEMLASEIRYR---ETAQD--LILD----IIDANKFILDM-GYPLDYFVGR-HLW-----DKSF-KNALKTD--IRYED
ETKQGNAISVEFVSNVYLVGN--I--IQCNIRNVTERKRAEDALALLSSITRHDIRNQLMALSGSLELSRKTVKEP-EGVANINRAYKAADTILRQIEFT
KEYEDLGVRS----PTWQRASDIIRSASLQLAA---------DSITFE-PE--DHLEIYADP-LLVKVFYNLFDNARQHGGAVTRISISDHP-GTGLTIV
IADNGVGIQQEDKSHIFERGFGK---------NTGLGLFLSREILSITGISISETGVPGKGARFEIAVPEG--------------
>tr|A7I549|A7I549_METB6 Multi-sensor signal transduction histidine kinase OX=456442 OS=Methanoregula boonei (strain 6A8). GN= PE=4 SV=1
MYRILYVDDEPGLLEIAKLFLERSGFDVTTMTSVGEAVKSPDVLLFDVIVSDYQMPGMDGIAFLKTIREKKDLPFILFTGKGREEIVVEAINNGADFYIQ
KGGEPKELAHKIRQAIRRRK-AENALAENRDY--LNQ----IFSS---GILVIDADTHRILDNPTAAELMHDS--RENIIGK-----------VER---T
SDKKQVPIISVML--SERKYDELAKSNEH--VRESEE-TLF-----------R-----GHSPRFSP-E-----------------------ISGKWVPFF
AEVS----IVRDITE-RKEAEEKVKESDRMIR---DSTFQ--GLLS----LLDANRTALEF-GLSYHEVVGR-PFW-----DEKR-QQLVRDA--GKFV-
RYEAGESVSGAWIVTDFSLKE--I--LIAEARDVSGLRKAEGAYRILASVTSHDINNQLTALDGFLELAKEGENPK-TTGEYLQKAQKAVERIRYQVGFL
REYESLGSHT----ATWQDVLACARSSARELDF---------SGISLV-RV--SGLEIYADS-LFPKVFFNLFDNALRYGTKMTRITLSAEK-ENALLIV
CEDDGDGVAADEKEKIFERGFGK---------NTGLGLFLVRDILSLNGITIRETGMPGKGARFEILVPPG--------------
>tr|Q2FNK8|Q2FNK8_METHJ Multi-sensor signal transduction histidine kinase OX=323259 OS=Methanospirillum hungatei (strain JF-1 / DSM 864). GN= PE=4 SV=1
MTKILYVDDEPTLLELGKMFLERTGCSVDTVSSAPQALKKLNSNPYDAIISDYEMPEMNGIEFLKTVRTSNQLPFILFTGRGREEVVIQALNEGADFYLQ
KGGDPKELYHKIRQAVQQRQ-VEEELRTKAEELTEEE----LRQNLDDATVVLEEDGIISLANNTFASMSGYT--REEIEGKPDDLSWMRIENFSGEIRE
IYLTIGVIPRSIADITQKK-----KSEAL--YRSVIE-DVY-----------SGATLLGKPIATLYF-NPDFLHSLCTNGFVRN-----YETRLRYVYYH
DESGAIAGIIRDITD-KKVVEQALVESERAHATMISNLPGFVYANDADYTMEFISDGCIAVTGYAPADLIHNNLIDLVHPDYQQTLWETFLYNGGMFEVE
ITKSGEIRWVWERGRGIFSEDDRLLFLEGFITDVTDRRRVKDALRLLTSLTRHDIVNNLLMLKGYQEIALETQELS-AVYDYISKAHEISNRIESIIGFT
REYEGLGMAN----SAWISVYSLIESAQAEVPT---------DIIKIENTIL-PSLKVFADP-ILQKVFSTFIDNSIRHGKTVTKGTFHSREVNGDLVLF
YRDDGIGIDPAKKEMIFDHGYGE---------HTGLGLYLAREIVSAGGFTIRETGTPGAGVQFEIVIPHG--------------
>tr|A7I8C0|A7I8C0_METB6 Multi-sensor signal transduction histidine kinase OX=456442 OS=Methanoregula boonei (strain 6A8). GN= PE=4 SV=1
MITILYVDDEESLLELGKIFLERNGFAVDIITSASEALTLIGQKPYDAIISDYQMPEMDGIELLKHVRASKTIPFILFTGRGREEVVIQALNEGADFYLQ
KGGSSLELAYKIRHAVQKRW-AETRLRDHERR--EAD----IINFLPDATFAIDKKGVIIAWNRAMEEMTGAR--PAEVLGKPMLADLILTPDLNGTRLH
IWGKASILLGAIEDITEQKYLELVRSERQ--LRESEE-ELV-----------FALQFFGRSVMTIVPAESGLTRMILDILNQPDV-YVVNENENVWIPIF
DNRGEFAGIGTDVTG-RREIETALRESAAKYQGIFAAESDGIAVVDRETGIIECNDALAFMHGYLKEELPGQ-------PITVLSAESDAAIAGATPFIR
HKKDGNVFPVEITVNPTRLQGREV--LIGAIRDVTELRRSEEALQLLTNVTRHDINNQLVALNGFLELLHEKVRDP-ALEEYFVWISQVSTRISSMIQFA
STYETVRKTH----PLWQDIRALAETTARQVSL---------GKVIIKNEIP-AGIEVFADP-LFLKVFYNLVDNALRYGEKLTFIRFSFIERDNGGVIV
CEDDGEGVPEASKEKIFDRGYGK---------NTGLGLFLAREILSLTGITVKETGEPGKGARFEITVPRD--------------
>tr|Q2FUG3|Q2FUG3_METHJ Multi-sensor signal transduction histidine kinase OX=323259 OS=Methanospirillum hungatei (strain JF-1 / DSM 864). GN= PE=4 SV=1
MISALYVDDDPSFLEIGKMFLEHSGIQITTAISAKAALETMQEQIFDVIISDYEMPGMNGIEFLKKIREKNIIPFIIFTGRGREDVAIEALNSGASFYLQ
KDGNPAALFIMVFELEKKNEELTLAASEEELRR-SEERYRLVMEATSDGIWDWNLKTN-AFFSDWYRMIGYEP----GEF--E-NYELLHPD-DVIRAEK
--EIQE-TRKD--KGFD-IEFRITKNGDYRYIHGRG-VDNEGNPCRVGSHIDIYRLLALIFMLLYEYISPRRCIAPHSLFE------SGELKWV---KSG
TITALQGIV-TDIT-ERKTSEEIVCEAMQKYETLFSSVPTGIIVTDENGAIIEVNQHAARILHVSREELIDKGIKN------------ENIAGIEIG--I
QNPNGEIAWIMATASLL--RLK--GY--GSVVDIGEQR---RSQALTMVNIRHDVKNSLTALKGFLYLLAEEI-DTES---LIGRIGSITGDIERKIL--
--FTSTQNIGA-ESPQWQNISH---LV-DALN---------ADGMKVVNELK--GLEVFADQ-MLGMVFENLIQNSLMHGEKVSQILLSKRQ-GQDLIIL
YEDDGIGIPDSEKENIFERGYGK---------NTGFGLFLIKEILSITGLSIRETGKYGEGARFEILVPQ---------------
>tr|L0HGW9|L0HGW9_9EURY PAS domain S-box OX=593750 OS=Methanoregula formicicum SMSP. GN=Metfor_2240 PE=4 SV=1
MISLLYVDDEPELLTLGKLFLEREGFMVTTTTSSPEVLNLLSTNTFDAIISDYQMPVMDGIELLKQVRERDTIPFILFTGKGREDVVIEAINNGADFYLQ
KGGDARPQFAKILTALERRR------ALAALK-DSEQKLASIIDFLPDATFAINTDGRVIAWNKAITMTGVKA----AEMLGRDQYEYAIPF-YSDRRPM
--LIDLVLSPN--DSFETKHYLDCHSGITLIWGKASRYDKDGNISGIESIRDIYRELVIILKLRITFFNENLPSLLENIVRDPERYAGNRVWIHWWNKDG
TLQGVLCVG-SDIT-ARRRMEDELRAENEKNRGLMSHAIDAIFIIDDSGRFTDANRRALDLLGRSPDDLKEMRYTDIC-PEAKTGTGSF-------PLTI
IDREGRHVSVISSTTRIDLGGR--PHMLAILHDISEIQMAH--DALQLANIRHDIRSQLTILGGYLQLLRDKP-REPDYTMYMKKVNDIVNTISENIE--
--FTKLQNLGM-IAPSWQNVHDVFFHACTRLD---------IRKICVQSDTG--DLEIFADP-LLERAFFNLAENTITHGGSVTTIRISAKKAHVGILLI
VEDNGTGIPSSDKEKIFSKGFGR---------NTGLGLFLVREILSISGITICENGEYRKGAHFELFVPR---------------
>tr|B8GGM9|B8GGM9_METPE Multi-sensor signal transduction histidine kinase OX=521011 OS=Methanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c). GN= PE=4 SV=1
MITVLLVDDEPNLLDLTQLFLEQDPIRAITCSSASDALKLLTERQFDAIVSDYEMPEINGIEFLQRFRQAGKTPFCIFTGRGREHVAIDALNSGADFYLQ
KGGDPKAQFAMVWQSVKRWQ------AELALL-ESEEKYRFLADYSLNGVMIQDFTGTILSANRMAEMVGFDDP---AAMIGRNTFEFIAPE-SQGQVID
--DLSNVLAGK--SRYE-ARYRLTCTGKKRWVKSIGTIEYRGKPANVSLQDITTRLFSCLITRGQVLIETLQQMPLHQILHTSLDFQDGNIVHALSILEK
KPATMLVLQ-KT---GSKFPSFSAKGKDLHYQAMMDSILAGVMLIDKDHRIVDINAAAAWMIGTPAEELIGSRCQDIC-PAMIMDRSE---------RVL
ITADGTRCSILKSVSPFWIQGH--QYLLESFVDITDRVKAE--HAINQANVRHDILNQLTVLRGYLTLTEDAA-EDAGISEYLRQIEKVARTIRLQIE--
--FTRDQDIGI-QAPGWHRIGLILDYVTSRLD---------SGKVVVENTIG--GLEIYADP-LITEVFYNLLDNALRHARLLTRITVSCRDVPEGLIIS
VSDDGNGIPLKEKEKIFERGFGK---------NTGYGLFIIRDILDITGITIQETGTFGEGAQFDLLIPE---------------
>tr|H1Z0R8|H1Z0R8_9EURY Multi-sensor signal transduction histidine kinase OX=937775 OS=Methanoplanus limicola DSM 2279. GN=Metlim_2136 PE=4 SV=1
PIRILILD-DGSIIKKDEEASIPDRFSFTTCKNREEALKILAEKEFDAIISEIKTPSYDGLTLLKKIRAENKIPVIFFTENKNPEILAEAINSGASGYYI
KRSPHQEITEKVIESAGKTRY-----TESNIS-----LISAVLDAVPGGIIASDTITK-FVFANEARTLGYSR----DEI--A-IHP------DMERVSG
--LFMD-TSGK--ADFA-REVPVRKDGTIFYADIRG-INGRKTAIAFS---DVFKHVISLSIVLVVYANP---LNPDGSYR------NGVISGL----SG
EEKCVLSVH-QDIT-DRILAEKALKETTDAFRTYIDNSYDAVLIHDTEGRIVDVNKKMLAMYGVTYEEALNHTIRD------------NNRIFFWQA--R
RPHDGSLFNVEVFLTRIELDNR--TFVLANVRDITERK---KEKALYLANVRHDILNQIMVFFGNLEFAIEDC-TDEN---YLRKMKKAVMSIQHQIE--
--FTKEDDLGS-KAPVWFSPGS---LT-FKDT---------NGIIPVKNEIL--DVEIFADP-MIDLAFNNLYDNAVRHAEGATGIRITGRP-NEDYIII
FEDDGCGILDEMKEKIFERNVGK---------NTGLGLFLIREILSITGITIRENGNLKEGARFEMRLPK---------------
>tr|J1L5I3|J1L5I3_9EURY Multi-sensor signal transduction histidine kinase OX=28892 OS=Methanofollis liminatans DSM 4140. GN=Metli_2114 PE=4 SV=1
MISLLCVDDEPAMLDLIKLYLERYGFAVTTASSAAEALDLFRDRSFDAIVSDYEMEGQNGVEFLGRLRGQGTTPFILFTGKGREEVAAAAMNGGADFYVQ
KGGDPRAQFAKIEVAVERHR------FTSALE-EREGIFRAITDKT--AVGIWMHRGEIIYANPAAEISGYSL----EELTSMDVWGFVHPE-ERAAVRA
--RAGKRLLGEIQPERS-LMRVLRKDGNERILDICADTLIAGSP-TIVTAVDIFSTLLSVVIIMVLYLNSFVHQDSVDDVLRDMQTVAGEIR-TVESIEF
HGEKAIALSLRDVT-DLKRASAGAREQERLNRELIAGMPE-YILVHRDGRIVFANPAAEGALGCETGGLVGEAISSVT-PEGRKAAPV---------EIM
IAGQGPEMPVILRAAPLTYQNE--DAVLLVLTDITERTVLEKSESLNLINVRHDILNQLTVLLGYLDIAGEEA-EGLPVLTYLHRVKRSALNIKELIE--
--FTRDQDLGV-REPQWCDVQRAIG----HLG---------LCGVRITSGLG--GLEVYADP-LFEKVFYNLFDNTERHGERATEIRVEWRQSDDGAMIL
WEDNGVGVRPEDKERIFTRGFGK---------NSGLGMFLSKEILAITGLGIRETGEFGKGARFEIHIPR---------------
>tr|H1Z0R9|H1Z0R9_9EURY Multi-sensor signal transduction histidine kinase OX=937775 OS=Methanoplanus limicola DSM 2279. GN=Metlim_2137 PE=4 SV=1
KIAVLFINYDPECLSETKKHLEKSGISVYCAENAEEAIALLNKNPFDVIVSGFVPTDSTGKSLLKYIKENNRIPYIVFSGDSGEDAVAGSFNNGADFFVR
RTGRPDDYYAKIFAAENRKRP-----SETDLF--NQERLRLVLEATNDGIWDWDLKTG-AFFSPRCTMLGYEP----DEV--P-SYSNVLPD-DLLKAEK
--VVYD-HNGR--DGFD-LEFRMTKSGEIRWMRARG-VDSDGKALRLGTHTDIFRKLFIFFLFLFVDANEVNDLDPESVIR------DGTIYTA---KIG
DEHYVLSLV-NDIT-ERKKAEEAISRSEKKYRDIFENSVTGLFKTTFNGEIFDVNNSFARMYYPDAEEFLKSG-KN------------GSVTGYEAI--H
KKRDGTPFWVSISGRLLCDDNR--KYCEGSIIDITERK---KEEALFLSNIRHDILNQITVIRGIADIIDDLE-DEQE---YIGKIDSAARTIEENIL--
--FTKEEQLGV-NTPEWISVSG---LT-DRRS---------FGKLPVHNLCE--DIMIYADP-MLSKVFENLMDNTVRHGEKATEVYVRCRH-NNGLVIT
WEDDGTGVPDEEKERIFQRGVGK---------NTGFGLFLTREILSITGISIKESGVFGSGARFEITVPA---------------
>tr|I7LM33|I7LM33_METBM Multi-sensor signal transduction histidine kinase OX=1201294 OS=MS2) (Methanogenium bourgense). GN= PE=4 SV=1
MNDLLVVDDEPDWLALVKLFLGQMGFRVDTRTSATDGLAALGQHQYDAVISDYEMPGMNGIEFLRAVRSGFRIPFIVLTGKGREEVVIDALNNGADYYLQ
KGGDPRALFAVVGRSIQLKN------AGETLY-EREQRYHDLQNAN-DLIQSVALDGHFIYVNNRWETLGYRE----QDVADLNVFDIVHPD-SLPHCRE
--IFQRLISGE--NVGI-IEVVFTSEGRKVFVEGMATRMNGGAPQSRGIYRDVNRRIVCIKVLLLLSMNSFWQEVSPEKVSETLEAAGESKYWDVVIARG
IPERLLATS-RDID-ERKRAEEVLRRSERELKVLLDSLPTGVVIVDATHLITDANATALALFDAPRGMVIGRHCHNIC-PANTIDRSE---------RIA
VTAHGEEIPVLKSVAKMHLSGR--ECLVESFMDISDRKRAE--EALMRANIRHDILNKVTVLLGYIALLRERV-NDPGVAQYLDILESTTNIIQSQIE--
--FSRRQEIGA-QEPRWLLVSDLLPY--LHLP---------PGVRMLTD-LS--GVEILADP-LLEKVFFNLLDNSVRHGGSVTSIRVYSTGGPDDTKIV
WEDNGTGIPDEEKERIFRRGYGK---------NTGFGLFLVREVLSITGMTITETGSFGTGARFEICVP----------------
>tr|H1Z0S4|H1Z0S4_9EURY Multi-sensor signal transduction histidine kinase OX=937775 OS=Methanoplanus limicola DSM 2279. GN=Metlim_2142 PE=4 SV=1
PVSILYVDDEPVLLDAGKLYIEHTGFTVTTCDNASDALNLLTENKYDAIISDYQMPECDGISFLKILRGRGDTPFIIFTGKSREEIVIEALNSGADFYLQ
KGGEPRSQFAKIHYAVSKRK------GEEALR-KNEELFRGLFDTITSGSAIYEVKNDVRDFNRMAEIEGRTK----SEVVGKSLLDLRPNI-DEYGLIP
--VFQRVWTGV--PEYY-PEKAYTDDKYASWYDNRVFLQTG----EVSVYNDVLKKVLGFVVIGIKDVNELLDMNITDIEHTLARIEDGSLI-DIEVLDT
HGGEVICFC-RDIT-GRRQAERALRESEAHFRDLFRNHAAVKMVIDKDGRITDANPAAVKFYGWSEEELKRMRIHDLT-PEIHFEFRH---------R--
-RADGSVRDVDVYSTKITINKK--TLLYSIIHDITERKQAE--SALIRTNIRHDILNKVMVLQAFLEFAGENC-ADNTRCGHLKKASDAASAIQRQIE--
--FTREEQLGV-HEPVWLPVAALLE----KID---------DRQFPITCSCP--EVLIYADP-MVEKVFYNLYDNTVRHAEGATGISVSCRPADSAFVII
WEDDGCGVPDDMKEKIFKRGVGA---------NTGLGLFLIREILAITGITIRENGVHGKGARFEMTVPA---------------
>tr|J1L467|J1L467_9EURY Multi-sensor signal transduction histidine kinase OX=28892 OS=Methanofollis liminatans DSM 4140. GN=Metli_1592 PE=4 SV=1
MISVLYVDDDPDTRGRVKFFLEAGGVSVLTADSADGAHVLLVDQRFDVIVSDYQMSGTDGIAFLKQIRAAGEIPFILFAERSREEAVIEAFNSGAQFYLL
KEGDQEECFSRIRQAVRRRG------GHEDLE-NS----------LPLPFFEIDIKGNILRMNRAAEAFLYSR----EDIRGVHHLQLILPR-ERVRACR
--DIETVISRD--LPHSQSNYIFRKDGSSFLIVDLTVMENEALLRTIHSMPDLFLRIE--LDYGIAEYSSSRAWQSAGGLREDQTF-GCERTFDIIRDDG
SRSGLVIIA-RDIT-EKKKAEEELIKGRQLLRAIIDNNPAWIACVDRDGRYLLANRNFCETFNLTTSEIVGMDGRDLL-PPPKYDIGSY--------TPI
TGSDGRVA-----------------GVVLMVNDVTELKRTE--TALSQANIRHDILNSLHVLYGYLDLASTSG-DEGEKTVFIGKAIEQVKKIRSEID--
--FTRDQDLGV-HAPEWQEPQKLLEQAWQFIA---------SGNVTLHADLE--GVAVYADP-MLGKVISNLIDNALRHGGAVTSITASFRLTPDGLIWS
VEDDGVGLSEDMKERIFLKGVGK---------NTGYGLFLAREILGITEISIRETGTSGKGARFEILVPP---------------
>tr|L0HBR8|L0HBR8_9EURY PAS domain S-box OX=593750 OS=Methanoregula formicicum SMSP. GN=Metfor_0164 PE=4 SV=1
MYSVLYVDDEPALLDIGRIYLEKSGFHVDVAESVDEAITKLEARPYDAIVSDYQMADTDGIQFLRIIRKQYDIPFILFTGRGREEVVIEALNSGADFYLQ
KGGEPKSQFAKILAAIDRRR------VHNELK-DSRKQLADLINFLPDATYAIDMKGHVIVWNRMMELTGIPP----AAVLGKGNIPSPIPL-YGNHGHA
--LADCIVRAE--EEPE-KAYPDRRSGDRLFWLTASPYDSGGRIVGIESVRDIYEHLALRQNYEVELHSAELAKSQEDLIRSEERYRGKLTFVN---RYF
GLDRQMCIG-CHHP-VIVPAEDAQRIKEELKK---VTRENPVVIID--------NRIIM-----SSGEIRWQRWSD---------------------RAI
FDTNGRII-----------------EFQSVGRDITESKRIK--QALQESNIRHDILNQLTVLLGALGLLELEI-ANPEQRRLISKAIQSSEIIRSQIS--
--FTQQQDIGV-HKPRWQNLHAAVTTVCMDEG---------YCIVDIDDSLL--SCEVYADP-LLRTVFANLFENAEMHGGKMTMIRVMGQETPYGYTIV
VEDDGDGIHNGDKQRIFQKGVGK---------HTGLGLFLVQEALGITGLTIREVGEYGRGARFEILVPK---------------
>tr|D6SLB5|D6SLB5_9DELT Multi-sensor hybrid histidine kinase OX=555779 OS=Desulfonatronospira thiodismutans ASO3-1. GN=Dthio_PD2897 PE=4 SV=1
-RSILIVDDEPEQRIIIKKILTSAGYRVLEAESGVECTELIRRQQPDLVLLDVKLGDESGLDICRQIKTDSDIHIMFLSGKTSPQEQARGLRAGADGYIV
KPVNKEEFLARIEALMRVVHTEERLKAQRIAKVGDWDVQTGNIVHHPDDWVFRKDGQILYVRTKASRVFATVQDVTQQIMARVRLSEINLGPDFNENIEK
LTALCNRLEGDPEDTPQGHIFDVIQKGSNLQETSYADTD--PNVTKYGLKTYIVGSICAVYIPVLRLIASAISANRKRA-EEALRESEKKYRQL---FEN
SPISLWEQDFSEVKKRLDELK---AQGIKDLEAYLKQRPELVWEMAGLVKVIDVNQGTLNLYKANFKDELLAGISRIFGKESYADFLLLIASGETSFSFE
VTLAGQNLKTQLYWSVIPYEVD-YSRVLVCIVDITELVNINQAKSEFLANMSHELRTPFNGIMGMMQVLQNTDLDD-EQQEFVNLSIQSSERFARLLSDI
LELSNIEAGKMIICPAHFSLQELLESLSGLFSAEGH-----QKGLALEFLMDSNPAEVIGDATRVKQVMFTLVGNALKFT-EQGSVQVQLTKGDVRVQFS
VFDTGIGIPEDRLSDLFNPFVQVDGSYTRKYQGAGLGLSLVKRLVDLMNGNISVESEVDRGTTVHVVLPFA--------------
>tr|B9XIC9|B9XIC9_9BACT PAS/PAC sensor hybrid histidine kinase OX=320771 OS=Pedosphaera parvula Ellin514. GN=Cflav_PD3360 PE=4 SV=1
---------------------MTN-STSETDHAAASAAETARTEQSSQARQQYRLLAENTVVGIWQINETLYINPAMLRMELEKPEDLAGLVLMANEHDT
RKVGEAELLSRNGRKLPVHVTLQSLIAEESARKSEELFPDGTLTFVNQAYSRFFIGKSFYIPEEDREMIRQ----KVRSLTPDHVFWQQWSFDKDGNLVG
RDITARIETEELRRSEENYRTLVEQSQDLIWAIDLQARFTFLNQAAYKTLGYRPEELTEFVPPYQAAFEENIRTGKFLVRKDGTIVALSANATVIRDSQG
NPVG-ITGISKDISERIRA-EQALKDSEKRYELAVSGSAAGLWDWNILTDEIYYAPRLRELLGYSQNEFPDRSVNEKLHPDDYERVWAAIREHLERRTEF
LTKTGDYHWFLGRGQALWEESGKPYRMAGSISDITERKYTEQERVLYVSGIAHDFNNILTVISGNARMARQDLAGH-SLQEHLTEIEKSSERATDLVRQI
LAFSRQQEMER----KPLYLAPVVEDAVKFLRSTLP------ASIEIRSNYESHLLPISANATQVNQVIMNLGTNASHAMNNNGLLEVRLDMQGRYVRLS
MQDAGSGIDTSILPHIFDPFFTT-KS---PGQGTGLGLSVVHGIMKSHGGAVTVETEVGKGSAFNLFFPAL--------------
>tr|B4D6V8|B4D6V8_9BACT Signal transduction histidine kinase, nitrogen specific, NtrB OX=497964 OS=Chthoniobacter flavus Ellin428. GN=CfE428DRAFT_4648 PE=4 SV=1
--KILIVDDIVSNRKLLRV----------EAENGVEALRLLEREAVDVI-SDILMPRMDGYRLCHEVRRLRDIPFVVYTAYTSPAD----MDLGADKYLR
KPA-PHELVAAISEA----L------TEELERSRAQSLEKGIIQWVNPAFTAMTIGQNPR------E---R-----WQT-----LYCDLHTRGKDGEITM
NDVTENRRKEAMRASETKFRSVFEAANDG-LIL--DGAFTDANTKTL-MFGLAREQLPGDISPAMGK--NALAGEPVLRRQDG------PIDVEVGLNRF
ELEGELLAITRDISERKRA-AEKLGRSVERLNLATHAAGLGVWDWDVQKNELIWDDRMYELYGLKKEHFSGATWIQHVHPEDAVRCDLEVQMALRGQKEF
RWPNGNVRQIKAYAEVVRDAGGQPLRVTGVNYDITERR----------HGVAHDLNNILAPIMMSVPLLRQQL-PD-TLDAVVSNIETCVERGARIVQQV
LAFGRGLEGER----LPLKIGAVIDEMMAIMRETFP------KDITLECLPVAKMPPVVGDATQLHQVLLNLCVNARDAMPGGGKLRLSATHPGPYVLLE
VADSGSGIPPEVVERIFEPFFTT-KE---TGKGTGLGLSTVHGIVRSHGGFIKVATEPGKGTTFQVYLPAS--------------
>tr|K2C5P2|K2C5P2_9BACT Uncharacterized protein OX=77133 OS=uncultured bacterium. GN= PE=4 SV=1
MQKILLIDDKRDNLVILAANLMPE-LTIISAQSGAEGIEKAKSGQPDVILLDIMMPDMDGYETCRRLTTTWHIPVILLTAKTNTASRVKGLEMGANSFLT
KPVDEGELVSQVRVALRIKQALEALVRTIALQESEHKWTHAKITFANNHFLSLTIGKDWFIPEDIRDEIRK----VLESINKENRLAISWSKTLNGEIIG
VDITERVRAETLKET----KTLLETAGRVAWSVNLKAKWSDEVAAIHEPAGYSPPVSISFYTPISRVFYDCASKGIEIITGKGKRIWVRATGQAVYDESG
KIIK-VEGSFQDINQQKQA-ENDLRKSEEKYRLLVENQTDMVVKVDPEGRFLFASPSYCRLFGKSEEELLGQTFIPFIHEDDRSATAEAMKTLYSPPHEQ
LTTRG-WRWLAWLDTAVLDEQGNIKEIIGAGRDITEHMQTESMITLFHDGIAHDFNNMLGVILGYSEMAMEILPSD-PAYAFLKEVLSAASRSRDITRQL
LAFARKQTISP----QVLDLNETVESMLKMLRRLIG------ENIDLTWKPCNSRCTVNMDPSQIDQILANLCVNAGDAIADVGEISIGTELPGNFIKLT
VRDSGCGMDKKTLSLIFEPFFTT-KS---IGKGSGLGLATVYGIVQQNNGFIDVCSMPGEGSAFHIYLPCH--------------
>tr|F2NCS3|F2NCS3_DESAR Multi-sensor signal transduction histidine kinase OX=880072 OS=Desulfobacca acetoxidans (strain ATCC 700848 / DSM 11109 / ASRB2). GN= PE=4 SV=1
-AKILVVDDESAVLEIIRKILVDRGYIVDVASNGLEALKFLEKSRYDLVLSDVKMPEIDGLELLQQIGLYPDLTTVMLSAFATIRDAVAAIKLGAFDYIA
KPVYPEDLLYSIERALKFN----------ELRQATQELEWTGLQVLELAP-----------EADEFQILESIRQEAKQIEDLNQLSEIFFLFDQEGDNQN
YDIDLKSIRPLVADVALEPRFYHHQKRKRYATNSFVVAPIIGEKSWG-------VINLAEFSPLVWLLARIFAEN----------LQHREYEAKLLKSSR
AELIDVRECFDHLST---------------------PVSMGLAVVDQNLKICYLNPTFVRLCDRRKSRVGS-EIFSFSDHKRLQQCFERIFQGEKAI-DC
GRIHGNSICLRFDSPAL----G--QQIMIVLEDITEISQMQQRLALLSTCVVHELNNPLDGVKRYISLLKKDSSED-VA-RYLSEAQKGLQKMSLAISSI
LNVANPNR---ILKTQLSQLREAVKILL--LQT--K-----EQRVEIVLS--TAPIFEEIFGTDLYTVFVNLIKNAIQAMSEGGKVEIIGQERKDDLEIH
FKDNGPGIDPKNLENIFKPFFTT-KS---EGQGLGLGLAICQKIVARYHGHISLQSVLGQGSDFIVRLPLP--------------
>tr|B8AD13|B8AD13_ORYSI Putative uncharacterized protein OX=39946 OS=Oryza sativa subsp. indica (Rice). GN=OsI_00217 PE=4 SV=1
--------------------------------------------IPALAILDVGLPDISGFELCRQLLQHPSLPVLFLTARSDEVDKLLGLEMGADDYVA
KPFSPREVCARVRTILRRMQKS-AAPA--------ETMRIGQFELNEPAARISWCGEVLPLTRYEFLLLKTFLQAPGRVFSRQQLMD-----------KE
VKPGVRRATEGLIDTA----TLLAEIGR---------DDLSGNAQQGKLAQAFSQLH-----------QRPFRANLGGIYKVRNEYMTDAQGRVVFDSAG
LAVGQDYSRWNDVWLTLRGKYGARSTQSNP----DDPESTGRVVFDSAGLAV--GQDYSRWNDVWL-TLRGKYGASTQSNPDDPE--STVMYVAAPVVEQ
GKIVGKPNS--AMAPVIHRSERRWLGIALLTTDSSELHKLENMRIRYVHALTHELKSPMAAIRGAAEILAEQP--PPVAARFIDNILVQNARMQSLVEKL
LAQARLEN-RVEITPEVIRVNSLFTRLADARSALLS-----AKAIVLTIQ-PV-PFNVEGDPDLLEQALGNLLDNAIDFTPQGGTIELAAREEQGQIQLV
VIDSGSGIPDYALDRIFERFYSLPRE--NGLKSSGLGLAFVQEVARLHQGEITLRNRD---------------------------
>tr|F5Q4C3|F5Q4C3_SHIFL Sensor protein phoQ OX=766157 OS=Shigella flexneri 2747-71. GN=SF274771_1476 PE=4 SV=1
--RVLVVEDNALLRHHLKVQIQDAGHQVDDAEDAKEADYYLNEHLPDIAIVDLGLPDEDGLSLIRRWRSNVSLPILVLTARESWQDKVEVLSAGADDYVT
KPFHIEEVMARMQALMRRNSGLASQV-----------ISLPPFQVDLSRRELSINDEVIKLTAFEYTIMETLIRNNGKVVSKDSLMLQLYPDAELRESHT
IDVLMGRLRKKFRHNKSLPPFAA-RATCS----NCADEKIT--ASFFPLSVRFLLATAAVVLVLAYGMV-ALIGYSVSFDKTTFRLLRGE---------S
NLFYTLAQWENNLHVEL---PENIDKQS----------PTMTLIYDENGQLLWAQRDVPWLMKMIQPDWLSNGFHEIEA--DVND-TSLLLSGDHSIQQQ
LQIKSSYMVWSLVIPLLWVAARETRELTSLVRNLNRLLKSERERYDTLTDLTHSLKTPLAVLQSTLRSLRSEKMSVSAEP----VMLEQISRISQQIGYY
LHRASMRGGTL-LSRELHPVAPLLDNLTSALNKVYQ-----RKGVNISLDISP-EISFVGEQNDFVEVMGNVLDNACKYCLE--FVEISARQTDEHLYIV
VEDDGPGIPLSKREVIFDRGQRVDTLRP----GQGVGLAVAREITEQYEGKIVAESMLG-GARMEVIFGR---------------
>tr|D9SDP1|D9SDP1_GALCS Multi-sensor hybrid histidine kinase OX=395494 OS=capsiferriformans (strain ES-2)). GN= PE=4 SV=1
--TVLVVDDNANLSLIAQLLLKIDGVSPVSFTDAMQAIIWCESNAPDLLLVDYMMPVLDGLEFIKRFRALPMVPVIMVTAAIEREVKLRALELHANDFIN
KPLDTVEFTARVRNMLALRK-MQLKFNEVNFEQIRQ----HELQYR--A--------VIETSKDGFLVV----DMQGRILETNDAYACLSGYSAE---EL
VTMNIGDLEAKMS--ASDVAHVLTGQGHARFETQHK--TWSGHIWPVEINVTYIAAEGGRCFSFLHDISQR---------------------------KQ
D-----------------------EAQLRKLSQAVEQSPNSNVICDTNGVIEYVNAAFTAITGYSASEAIGRKTGSGLTQPEVYAALWQTLQQGEVWQGE
INKNGEYTDFAI-VSPIRQADGEITHYVAIQKDITQKKLLEKAKSEFLANMSHEIRTPMNAIIGFNELCLRTQLSD-KQKDYLTKAGSAAQSLLHIINEV
LDLSKIEAGQHMLEAIPLKISRVVKNVTDLIGVLAV-----DKGLTIHVDLDEHQYPLRGDPMRLQQILLNLCSNAIKFS-TQGSISIRCQLGAVELKFA
VQDSGIGISPAQLGLLFKPFSQADSSTTRRFGGTGLGLSICRGLVERMGGRIWVESEPGIGSTFCFTVRF---------------
>tr|I7A5S5|I7A5S5_MELRP PAS:Response regulator receiver:ATP-binding region, ATPase-like:Histidine kinase A-like protein OX=1191523 OS=Melioribacter roseus (strain P3M). GN= PE=4 SV=1
--KILYIEDNFFDQDLVKNCLEEKGFEVTIASTASEGMVYISKNEFDLILLDNKLPDMNGIEILKKLGNVKETPVIIFTSKGNDELVVESLREGAATYIS
KASSYIDLLPPLL---K--KTIEEF------KSGVSRST--RLSSLSKKYIERTH-TDIDLTREKFEIAPNLA--IDAVDSTEKGLEILSQNDY--DIVL
IDLRMQRLREIKLRGIKIPVIILTGYG------------------DEEVAMAA--IHLGFDYIYLLQLPYSIYNAINRFNTL-----------SINESLQ
NELIKLNRSLEERTNQLKEEFEERKKLEQKYRDIFYNHSAVKILIDETGEITDINKSAEKFLNVSPDKLIGTKAAEILKNGKPFKLRRAIEQSPVTVVIT
LNLSGEFLYWAVIFPVINRAGN-ITNYVAIKEDITEKKKMIEVKSIFFANMSHELRTPFVGIMGYAELLRELLDVD-ELREMAEGIYRTSQRMVDTLSKI
LDITKIESEKIEVKYTEVNIRRLLEDICNEYYAAIK-----SKNLYLKKDFNNLPDKILSDEKLISEIISNLISNAIKFTS-KGGIEIKAETRMNFLALS
VSDTGIGIPREKIDLIWEEFRQVSEGSSRDFQGTGLGLTICKKYTELLGGKISVESEYGAGSTFLVEIPL---------------
>tr|K9VL88|K9VL88_9CYAN Multi-sensor hybrid histidine kinase OX=179408 OS=Oscillatoria nigro-viridis PCC 7112. GN=Osc7112_4398 PE=4 SV=1
--TILIVDDDAVDRMAIKRSLKSAGVSVTEAEDCADALAKLFESKFDCVLLDYGLPDGDGLSLVKNLREAGKVPLIVLTGQGDEQIAVELMKAGASDYIA
KNKLSPDSLSRSLYNAMR-----VYRAEYKAFHTSQKLK---------------------ESEERYRLVLEGV------------NDGIWDWDLSKNE--
VY-WNDRLLEIIG--LSRQQ-------FGRTMEALDKEGIVAAIAALEQEIDYNVE---FRLLGVYRYCTSQGKAQRNSQGKPLR---------------
-----MAGMISDITER-KQAEDALERERQQLRQIITCVPVAMAMFDTQMRYMANSKKWISQFNLKLPSLNNFSHYELFPDPNRWKVMQEVLKGQVVSVSE
ERADGSVLYLRWAAHPWYDPDEKVGGIVMVADKINELVEASRVKSQFLANMSHEIRTPMNGVLAMAQLLLRAPLEQ-KQRDCIQTIYRSAEHLLNVINDI
LDFSKIEAGEMRLEKYNFDLDSCLESVIEILAHLAE-----EKGIELNILVDSSPRKLVGDSGRLKQVLLNLTGNAIKFT-DRGQVLVHVTVKEARLLFS
VRDTGIGISAQGQTKLFQSFSQVDDSPTRPYGGTGLGLAICKQLVEMMGGDIGVRSLLGSGATFWFTVPLE--------------
>tr|D8G3M2|D8G3M2_9CYAN Putative Histidine kinase OX=272129 OS=Oscillatoria sp. PCC 6506. GN=OSCI_3350028 PE=4 SV=1
--KVLIVDDDEVDRMAVRRALKIAGVRIAEAGGSAEARVL-----FDCAFLDYRLPDGDGLKLVKTIREAGKIPLIVLTGQGDEQIAVELMKAGASDYIA
KAKLSPENLSRSLQNAIR-----IYRAETKATQASQKLK---------------------ESEERYRLVLEGA------------NDGIWDWDLSKNE--
VY-WNDRLLEIVG--LSRSE-------FGSAIEAFDYESTRKALEALETGTEYNVE---FRLLDVYRYCTGRGKAQRNQQGKALR---------------
-----MAGIISDISDR-KLAEAALERERQQLRQIIACVPVPMAMFDKEMRYQAHSQRWLTQYNLEGQSILNRSYYEVLPDPDRWRKMERSLTGEVVSVSE
KREDGSTVFLRWAIHPWYAPDGEVGGIVLVSDRINELVEASRVKSQFLANMSHEIRTPMNGVLGMAQLLLRLSLEA-KPREYAQTIYRSAEHLLSVINDI
LDFSKIEAGEMRLETLDFDLDVCIESMVEMVVATAE-----EKGLELNVLIESSPRQLQGDPGRLKQILLNLVNNAIKFT-DRGQVLVRVSLKDRKLIFS
VRDSGIGISPEGQKKLFQSFSQVDGSPTRQYGGTGLGLVICKQLVEMMGGEIGVRTSVGKGSNFWFTIPLQ--------------
>tr|B4CVM2|B4CVM2_9BACT Multi-sensor hybrid histidine kinase OX=497964 OS=Chthoniobacter flavus Ellin428. GN=CfE428DRAFT_0709 PE=4 SV=1
--ALALLPESSRGCVLFVDVLQEAGFEA-FGVSGEECLA-LHLRLPDLILLDINLPDIDGRDLCRQLKEDSGIPIVLTGGRISSEEQAAGLEAGADGYI-
---SNHELVARVDAILRVKRTEAELLEQSE--QRYRSL----FEHNPDAVYSLLTGYPHRVLAR------------GE----------------------
VDGKIVGAFCIAQDVTQKSEER-----FQQLAENVD--D------AFW----ILDVATQRM---------------------D-----------Y-----
-------------EGIARDITKEAEDLIGEQAALLDNAQEAIYVQGLDGVIKFWNRSAERTYGRHAAEVIGSRLLPHAAHDSDTARRQVLEQGKWIGELE
QIGIGREITVEGHWTLVRDAEGEPKSILCINTDITERRKLEAQRMTLAGGIAHDLNNVLSPIVM-SVDLLKMKTDDPACLEVLETVETSARRGADMVQQV
LSFARGVEGQ-RI---IVQPKHLLKEVQKIVAD-----AFP-KNIELKLSQKPDLWNVLGDPTQLHQVLLNLCVNARDAMPEGGRITIAAENAGPHVIIQ
VQDNGTGMPSALIEKIFDPFFTT-----KELKGTGLGLSTSLAIVKSHGGFILVSSEVGRGSTFKIHLPA---------------
>tr|B4D8T1|B4D8T1_9BACT Multi-sensor hybrid histidine kinase OX=497964 OS=Chthoniobacter flavus Ellin428. GN=CfE428DRAFT_5321 PE=4 SV=1
--NLLIAEDNPDDADLLIWALRGAGFEFYHVVKEEDFLRWL-SPSLDLIISDYEMPGFGGMRALELKQLAEDVPFIIISGSIGEEMAVEAMRRGATDYLL
K--GCSRLESAVTQAISQRRLRHEQLRESE--ERFREV----VQNIEQVFWMTIWGHTLEAIHRERVLAAALTRQVGSYVRPD--GAVRWISDRAFPVRD
ADGNVYRVAGISEDVTERAQFD-----LQLFRKLVDSND------TFE----VIDPESGRFLDVESGFTRE---EYLKMRDIPGEAVTGEARHYCTAYPI
EFNGKLV----QLEAVIRDISKLSEERMREQAAMLNLAHDAIFVHGYDGLITFWNKGAENLYGWSADETLGNHFREFIDIDSAQRNAELLIKDEWHGEIQ
TDRQGKKVIVNSRATLVRDERGKPKSVFLIHADMTEQRELEARRMTLASGVAHDLNNILSPIMM-SVPLLRRNLEKETFENVISTIELSATRGAEIVKQV
LTFGRGLDGV-RR---PTSLASIIQEIIKILGQ-----TFP-KDIRIETELAPDLWRVVGDSTQLHQVMLNLCVNARDAMPTGGKLRIRGKNAGPNVILE
VQDEGTGIPPEIVERIFDPFFTT-----KGLKGTGLGLSTVLGIIKSHHGHVGVSSQTGFGTTFRIHLPA---------------
>tr|B4CVM1|B4CVM1_9BACT Multi-sensor hybrid histidine kinase OX=497964 OS=Chthoniobacter flavus Ellin428. GN=CfE428DRAFT_0708 PE=4 SV=1
--YALLVEDSEDDALLLVEALSRGGFAP-KRVDEEGMRA-LRSREWEIVFCDYNLPNFNAPSAIRVLRECGDAPIIIVSGAVGEDVAVESLRQGANDYL-
---NNRRLVPAVERELRESEARRGQLRASE--ERYRVL----FERNPVPMWVYHYGYSLDLRP-------------GE----------------------
TQGTTKARIAQALDITERAEKE-----LTRIKMAVD--D------AIA----ILDDASIS----------------------T-----------S-----
-------------RIVCTDLRKRAQGKIEEQAALLDHAQDAIIVHDLAGRIKYWNKSARRVFGWTPAEVTGRRVQDILYSTPEEAMVELLRTGSWTGDLQ
QNRDDKEVLIEGRWTLVRDEFGDPKSVLSINTDITAKKKLESQRMTLAGGIAHDLNNVLGPIIM-AVDLFRLKMTDPQDLELLETVSVSARRGADMVKQV
LSFARGLEGQ-RT---LVRPVQLLKEVQRIARD-----TFP-KFISVDITTAEDTWSLLGDPTQLHQVLLNLCVNARDAMPQGGRLTLNACNPGPHVVLE
VADSGTGMTPDVIEKIFEPFFTT-----KEVKGTGLGLSTTLAIVRSHNGFVTVESHPGKGTKFRVHLPA---------------
>tr|B4D4F3|B4D4F3_9BACT Signal transduction histidine kinase, nitrogen specific, NtrB OX=497964 OS=Chthoniobacter flavus Ellin428. GN=CfE428DRAFT_3791 PE=4 SV=1
--RILLVEDSPTDALLIEHELKNGGFDVITCVSESDIRAEL-LREHDLVMADYSLPGFTAMDVLDWFRQSGDAPFVLVSGTIDTETAVNSMRRGAADYIL
K--RNAALPGAVHRALERQKLRREKIAEEK--VGFLAS----MLNLAQAIIVCLYGWTHEFILMEACMLKALVRH-GEWVRRD--GEQIAVSERATLARD
PDGNPSAILFIHHDITARAEEQ-----IRYQEALIRTGEIARGSWEFN----FLTSEVARIFELDVGFSRE---HLRRIRDAAAEIITANDRQKWVGHPV
IENQSIA----RVRGILQDITKENEKQLHDQARLLDFTTDAIIVSDFTSEILYWNQGAERMHGWTAAAAMGRPACELLSLSKDEILREVSLHGEWSGELE
RTKDGREIIVSSRATLIRDDAGLPKSILSLHSDVTEQKVLESQRITLASGVAHDLNNILSPIIL-ATPLLVEEMSDEARRSIVQTVQTSARRGVEIVRQL
LTFARGVRVE-RM---PVNCENLIAEIVSIAEE-----TFP-KSIAITVKAKPGLWTALGDATQLQQVLLNLAINARDAMPSGGSLNILARNTGAYLLLQ
VSDTGTGISKAIIDKIFDPFFST-----KEVKGTGLGLSTVVGIVKSHGGFVNVESEPGRGTTFKVFIPA---------------
>tr|A7HCX1|A7HCX1_ANADF Multi-sensor signal transduction histidine kinase OX=404589 OS=Anaeromyxobacter sp. (strain Fw109-5). GN= PE=4 SV=1
--PVLVVDDSVTAREELRAALEHAGLEVVTAGSAEEGLLLAAELRPRAIVVDGVMPGMDGAAFVQAIRADATTPCILLTASGS-VGELRALDAGADAYVR
KDEDGNEVLARLQALLRS-ATSATSVAAPGALPAPRRVSAGASTLLSDVAEARQEGHDVSAT------------------SPEEALALL-------AVDR
VDAIVESTRA----GEEGAAACLRIRGDGRWRH---------------LPV----LVL------GA-----RAEP----EATVEALAGG-ADDYVPV-AS
GPLVARAR-VN---AQLRRSQENRTREYVRSAAILETISDAFFAVDRDWRFVYVNHALESMVRAERDAIAGTTLWDQCPFGARAELERAIDSQVPVTFEA
RGPGDRWIEVRA-FP---HR----DGLTAYLRDVTERRRTQEVQAHLLGITGHDLRTPISVVRVSVDVLRDAQLSE-RNRRVLSRAAGAAARMSRLVNDL
LDYSRARLGKGPIAPRPSDLDAICRDIIEEVSS-AH----GGRRIAYQPGVDG---AGEWDPDRIGQVLSNLLTNAVRYSPEDAAVSVAWHALDDRRVIS
VHNEGPPIDQALLANLFEPFERG---RTAASGGTGLGLFIVREIVRAHGGSVAVASDAGSGTTFSVSLPA---------------
>tr|Q5UZS4|Q5UZS4_HALMA Putative light and redox sensing histidine kinase OX=272569 OS=B-1809) (Halobacterium marismortui). GN= PE=1 SV=1
-IRVLHIDDDPDFVAVAADSLEAADISVETATSARDGLDRLAQNGFDAVVSDYDMPKMNGVELLDAIRETNDLPFILFTGKGSEEVASEAISVGVTDYLQ
KSFGVELLANRIENAVSEYRAK-QQAAKSERRVETNDILWADLEVINSAYVAKLRENPFLI-HP--EDRELMKDTMQSLMDGESRVRWVQGEPVAGFA--
RDITERRNHEKLYEISADEEKIVTPLSEAYCRKMIDTGSVMGEYETYISSERVCNAHSGTLLDVFYVLDSDWNESLLNVTYSAAEVFPEEYRDLVSFEGG
TTRVELAGIGRDITE-RQAREQELTRTKELLGQAQRIASVWEVDVTSDPPEMTVTSEFYRIHGLTPDDELRIDSIDLYHPDDRETVRTEFHETAEGYDME
VRIGDHYRWVRA-LCKPVTENGDVVKLRGSVQDITDRKLRERLEEEFTSIVSHDLRNPLSVAEGRIELAQQ-EYDSE----HLDSASDALARMRTLIDDL
LAAARDEQ-SA-VDTGVVALSDAAEQCWHNVET-N------EAELTVETD----AI-VRADRSRLEQLLENLFSNSVEHG--GNDVTVTLGDLDDG--FY
VEDNGEGIDEEDRSRAFETGYST------SDAGTGFGLWIVAEIADAHDWTVTIGESSEGGARFEITG-----------------
>tr|Q3ITX9|Q3ITX9_NATPD Receiver/sensor box histidine kinase OX=348780 OS=Natronomonas pharaonis (strain DSM 2160 / ATCC 35678). GN= PE=4 SV=1
-IACLYVDDDAALAELTQEFLERERITVETVSSASEALDRIDDTEYDVVVSDYQMPEMDGLEFLETLREDRDVPFIIFTGQGREEVAMEALNLGADRYLQ
KGGDTAVLARAIEQAVAHRQAS-ERLEEQNRRLIIGDAVIADGRRLNDVARADAAGRPVFI-SE--ETRQPAENPVEQVLDSGELIRYISAAPVVLVF--
RDVTDEYEAQDLSTAPSVEAACLDADCHGAYVEAIEARRSLEGVESLLDGTRSRGEVVGIVFEAVIEWTRDWNSRAEELFYTTAEAIPGGIEPEVQLDEG
ENRSRVLSLVRDVTE-EREQSRQFRALVENTNEAV-------FIKDTEGRYEFINEAGADYFDADPSDIVGTHDGDLFDLDDDRRLLEADRSSEEPVAEE
QTYGEEYVFLSE-RRPHYDEYGNLRGLVGISRDVTDRKRTETLREDIIDVLSHDIQSPLSAARGRLDLA----GDSE----HVDRAARLLEDIDVLVEDA
LTLAQQGW-EI-SATEPQNLAAVTRRVWQRLDA-D------EATLVVADD----EPLVAADESALELLLQNLLGNATEHG--GEGVTVTVGCVNDT--FY
VEDDGPGIDRADREQVFEHGYTT------AGDGTGLGLTIVQRIADAHGWSVTVTESDAGGARFEISG-----------------
>tr|C7NUQ8|C7NUQ8_HALUD Multi-sensor signal transduction histidine kinase OX=519442 OS=Halorhabdus utahensis (strain DSM 12940 / JCM 11049 / AX-2). GN= PE=4 SV=1
-VRILHVDDDPDFLDITAEFLQRENFTVDVATSAADGLDRLTENAYDCIVSDYEMPGQDGIEFLKAVRKDHDLPFVLYTGKGSETIASEAISAGVSEYLQ
KGSGTDVLANRIENLVSRREAE-ITVARYDQREE------------------------------------------------------------------
----------ELLDITADDEKAVTDLSKTYCRQTIDSDSIFGELGCYIGRKLVEGELFGTLLNVLYLINPDWNDRLGAVTYDDEEIFPPEERERIALATG
RAVVEVVGIGRDIAG-HKERERELRQYQQILDAMLDPATV----MNEDGEYTVVNNAMAAVHEMQAEELIGEPSRELREARSDDPYRELVDEEYRG-EYT
MEIADPIYFEYR-LSR-LTIDGRFCGIVAVGRDVTDRKRREELEEEFASLVSHDLRNPLNVAEARVQLALD-ERDSE----HLDVAAKAIDRMGVLIDDI
LQLAREGE-RI-DEMERIDLETICADCWDAVET-T------EATLSVESN----RP-IRADRSRVRQLLENLFRNAVEHG--GEDVQITVGALEEG--FF
VADDGPGIPPDERETVFESGYTT------REDGTGFGLAIVAEIADAHGWDVAVTDSEDGGARFEITA-----------------
>tr|G0HUH2|G0HUH2_HALHT HTR-like protein OX=634497 OS=102182 / NCIMB 2187 / VKM B-1755). GN= PE=4 SV=1
-VRVLHVEDDPEFASMTAAFLSRTDFDVISATSAKEGLTRLSEEPIDCVVSDFDMPGQDGIEFLESVRAVDDLPFILFTGKGSEEVASEAISAGVTDYLQ
KQQGTDILANRIANAVEQYRSQ-RALDASRKRLLSPLGVIESFEQVNEKGEADLVGKETLV-PD--SALDAVEETITALQEASGLDQIVWHNRIFSQF--
REITERRQRQKLMHAESREAVAPTREGDSLVWEVFESGEQRPNPDTDISSELIPLGDHGVLLEGVWDWNVKFDERWADMLYSLDDLIHPEDRERTYFDGE
TEIYEAVGIHQDVTD-HKERKQALEDTSRKLQVILDTAPTYILMKDTDSRFLFINSAARDLYGIDADESVVGTSYDILPDHIAEQTHADDQEQKETVEVE
TVIGTERTHLTR-KTPILDEDGEPYALCVVATDITEQKRRERLEEEFASIVSHDLRNPLSVLEGSLALARD-TGNDE----QFDRCYRAIDRMKELIEDL
LTLAREGD-TV-SETEPLALESTVLSCWQAVET-S------DATLEVTAE----ST-IYADESRVRQLLENLINNAVTHG--GPAVTVEVGDLTDG--FY
VADDGGGIPAEQHETVFESGYTT------TDGGTGFGLAIVKEIAAAHDWSVSVTESDDGGARFEFRG-----------------
>tr|H1Z2M3|H1Z2M3_9EURY Multi-sensor signal transduction histidine kinase OX=937775 OS=Methanoplanus limicola DSM 2279. GN=Metlim_2375 PE=4 SV=1
-ISVLYTDDEPALLEIGKIFLEKTGFTVKTATGADEALNLLEKEKFDVIVSDYQMPKMDGIEFLIEVRERYDIPFILFTGKGREEIVIQAINSGANFYLQ
KGGEKSELSHKIKSTAADKKTR-DALRQSEEQSAMPEPVLQDGIYANPVANDEVIGQNDFI-PE--ENREPIALNMAKRISGDTDIHHARTAPVILA---
-DITKRSREEAIFENT--------------------------DLKAYEFR-DRSGKVKECINEA---EEELMLAESENALMNEERLYNPDNGKIWAILPD
-PGWEIMGIIRDITE-----ENAGKEELNLKNYAIDSATDAIGIGDLSGNITYANPAFLSIMGYSPDEVIGSTFRKF---EGESVY---------G-EIM
GKKGTPKILWFN-ANMIRNDSGQPLALMFSFRDITDLKRTEELIKLITGITRHDIKNQITALTAYLELTKFYI-------------IDKADIP---IVSI
IEKTKSIE-SI-GIDEP-----------------------------------------ILTD-VLDRVYYNLIENSLRHG--GD---FF-EKSGDD--Y-
-SDDGRGIADEEKEKIFEKNY---------GHNTGLGLYFTREILAITGISIRENGIYGRGARFEIRV-----------------
>tr|H1YXJ5|H1YXJ5_9EURY Putative PAS/PAC sensor protein OX=937775 OS=Methanoplanus limicola DSM 2279. GN=Metlim_0842 PE=4 SV=1
-IRILHVDDEKSLIDLTKIYLEKKGFRVTSASSVSEALKILESDCFDVILSDYEMPHIDGIEFLKTLKAGGPTPFIIFSGRGREDVLIEAINNGADFYLQ
KGGKTAELKNMIFQAYSRKKAE-IELKKSEERYAQTELICPDGTFVNDAFSQKIVGEIPNI-PD--SEQNAIRSHLKSLTPENPRIRWQWNDTEYQSV-G
RDMTDQKLMEALMYTI--------------------------HLQQYEYQ-NSMGEILDVLKDPFFFRDEYCNKAFEELVLSRDEIFNKDFADFYAILNN
-QQYEIVGVILDISQ-RKNVERDLKREINFIQALKDTIPAPVFYRDINGIYHDCNKAFEELVGLSKEEILGRNIHDF---DLADLY---------QYEHK
INNGEIIDVMFS-KTALHNPDGSVAGIVGVILDISRRTRMEELSNLLSNVTRHDVLNQVTAVLGYLELIREFV-------------VSKIEIL---IQHQ
LLFTKDYQ-EI-GITTP-----------------------------------------ILAD-LLKKVFYNFAENSLRHG--GG---FT-EEENGF--L-
-EDNGGGILYADKDKIMLKGF---------GKNTGYGLFLSHNVLSMTGMSLRECGVPGEGVRFEITV-----------------
>tr|E1RHZ1|E1RHZ1_METP4 Multi-sensor signal transduction histidine kinase OX=679926 OS=Methanoplanus petrolearius (strain DSM 11571 / OCM 486 / SEBR 4847). GN= PE=4 SV=1
-IKVLHVDDEPALVEITKGFLEKSGFEVTTFTSAVDAIKDLETTSYDVLISDYEMPALDGIEFLKRLRGKGDTPFIIFSGRGREDVLIEAINNGADFYLQ
KGGKKAELENMIRQSVSRKMAE-KELKKSEERYAQTELICPNGTFANDAFYDALIGHKHDV-PE--EEIPSLKRHFSDLTPDDPRVRWQWSDREFQSV-G
RDVTQQKLMQALMDTM--------------------------HIQQYEYA-NSRGEIIDVLMDPVFYRDTKCNRAFEELVLSKAEIFEKDLADHYAIVDN
-QLYEIVGVIMDISE-RKKMERELIEEVNFVQALKDTIPAPVFYRDVNGIYHDCNLAFEELVGLSRDEIIGKTIHDF---DLADVY---------QYEYA
INNGEIIDVLFS-KTALFKADGSVAGVVGVILDISNRKQMEKLSNLLSSVTRHDVLNQVTALYGYTELARELF-------------LTKMEGL---IERQ
ISFTKDYQ-EI-GIDTP-----------------------------------------IFAD-LFNKVVYNLIENSLRHG--GE---FS-EEKDDR--F-
-EDNGKGISYENKEKVLIKGF---------GENTGYGLFLTENILSITGMKIHECGVPGEGVRFEIDV-----------------
>tr|E1RF62|E1RF62_METP4 Multi-sensor signal transduction histidine kinase OX=679926 OS=Methanoplanus petrolearius (strain DSM 11571 / OCM 486 / SEBR 4847). GN= PE=4 SV=1
-IKILYVDDEPVLLELARIFIEKSGFSVDTAESAALALELMKTGEYDAVISDYQMAGMDGIDLLKAIRASGKIPFIIFTGKGREEVVIQAFENGADFYIQ
KGGENSELVHKVRQSIALRQTE-AALKDSEEKYLANEAIFQDHQFSNPRFPGEMVGKSDLIHPD--DREMVLGRYERRITGKSARVHWVHATPIILD---
-EITERKAAEELNEEL------------------------------------------EILVEGIWEMDNRVNKKMAEMLYSTKEMHDEDQKDHLSKGGE
-GLYVSFAMVSDITE-QKYAEDALRESRQDLMDIIDFLPDATFVIDNHGRVIAWNRAIEEMTGVRSEDIVGRGNYEY---ERKPIL---------ESHYP
SVIGNRLVLWFI-ATPLYDSSGKITGAIESIRDITAKREFEELEKLLYSITRHDILNSVMAAYCFIELLKNPY-------------IETLHEL---IQKQ
IEFTREYE-NL-GSHVP-----------------------------------------ILAD-ILRKVFDTLLDNTVRHG--GG---VS-RSENGG--Y-
-KDDGTGIPDDDKELIFERGF---------GKNTGLGLFLAREILAISGVEIKECGSPGKGARFEMTV-----------------
>tr|A7I8C1|A7I8C1_METB6 Multi-sensor signal transduction histidine kinase OX=456442 OS=Methanoregula boonei (strain 6A8). GN= PE=4 SV=1
-KEILIVEDSHVQAEILKHILDNAGYTCQVAENGERALEVLARKIPDLIISDIIMPVMNGYDLCREIKKTKNIPLILLTALSDSRDIALAIESGADNFIT
KPYPADYLLQRIRKILERPPISEKADAGSVPFLKTYSIGMDRVRILLSAYEA------AVIQHREFQILNQIISVSNSSMKPDALLESI-----------
-------------------------------------LHKALSIQGFEMGALYLNNTGKT---EATMICYQETAPASSDLRVMGVLNFGEPYQELCIRGI
PQFVDLSKDT----------P------------------------VSRDSIILRDLGARSLA-----LLPLVSASTVIGA------MAFISTRKHDFS--
---DQE-RS---LLSLISTEIGN---AV---QKILLLKRLEQETNLYLDIMSHDINNVNAGALMQLELLYES-LDAE-NRKMAETIMRAIDQSVEIIGNV
STIRRMHEQKAALR--PIRLDEVIRAETGRYSGV-------------IFHYAGTDAVVMA-DDLFGQVFTNLIGNSVKFCTENPEITITVEDRAEQVQVT
VADNGPGIPDELKPEVFDRFRKG-KS---KKSGKGLGLFITRHLIEGYGGRIWAGDRFGQGAAIHFTL-----------------
>tr|B8GHQ9|B8GHQ9_METPE Multi-sensor signal transduction histidine kinase OX=521011 OS=Methanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c). GN= PE=4 SV=1
-IKVVIVEDSPTQQEYLRYILEKHGYTVFAATNGQQALDLIGEVRPDLLISDVIMPVMNGYDLCRAIKSSQEIPVILLTALSDTKDVALALQSGADNFIT
KPYNEEYLILRIRQILARALRMKDWMQSPVPVSEVYQISSDRGQIFLTAYQV------AIMKNQEAIVLNQIISLCNTTLSLDELLELT-----------
-------------------------------------IQKILNLFGFEFGALYLINEERT---CAHLRHHVETIPVEESYLDIQTLDMGLLNRGVLLNGI
PAFFTIDQTT----------F------------------------YEREKIIFKELGAKAYA-----MVPVKFGSEVLGV------LALTSKNEHEFS--
---DVE-IG---MFESVGREVGS---AV---QKALLQERVTTEMSLYLDIMTHDINNVITSSMGYANLLEDE-LTGP-QYEFVQKIRTSLDQTIEIIRNV
STIRRLHEKQARLV--PMDLDAVIRNQISRFSEI-------------PFTYPGTGVMVYA-DDLIGQVFTNLIGNSRKFAGDEVSITIGVEEDEGVVEVT
VADNGPGIPDDQKAQIFDRFQKG-TT---SKSGKGLGLFITWMLVEGYGGTIRADDRDGPGTAIHFTL-----------------
>tr|D5MGF6|D5MGF6_9BACT Putative Histidine kinase OX=671143 OS=Candidatus Methylomirabilis oxyfera. GN=DAMO_1779 PE=4 SV=1
---AVVVNDDLSQLLLTSKLLEKDGLHVRPCRGAEEALAVMEQGPPDVIVTDLYMPGVDGWRFCRLLRSPY-IPILVVSWTFSGADEQIAANLGANAFLS
APYEPSELRASVQALLEGRLSMRTLIVEDS---PMQ------SKILSRAFA--AHGYTVFTAST--------GEEAR-RLFRDHSPQIAI-LDYH----L
PDITADRLLEEFKQA--------------------------------AVRMVAI------------MITANPSPELQFMRMGADGHVRKPFDPHLIDLCE
KAWRE--RSLLAVEDLLEERTRQLRERERQYAQLFENANDVIYTHDLSGRFTAFNRMAEQITGYTRSEALTMHVAQVIAPEYLGLHHEITAQNVRGEISR
LERGGHRVPLEVSSGPIYRNGE-VVGVQGIARDVSEQKRLEQAQKTLAGGVAHDFNNLLTPILGYSRLLKRGQPGEDV-YQAAQVIEGAGERCAQLANRL
LGFARGGKHQE-M---PVDLHTAAREVVDLLSRTID------KRITITQRLCVEQAVALGDPSQIQQVILNLAVNARDAMPHGGNLHFETDTVGDYVMLS
VTDTGMGIPQEIQGRVFEPFFTTKEPG----KGSGMGLAMVYGIVKNHGGTIRVYSEEGSGTSFKVYWPLA--------------
>tr|G2HBI4|G2HBI4_9DELT Sensory box protein OX=298701 OS=Desulfovibrio sp. A2. GN=DA2_3140 PE=4 SV=1
---VLVVEDNHDMNDHIAG-ILRPQYDVARAYDGEEGLRKALDLRPDLIVCDVMMPRVDGRRMVEQMRRYADVPVLMLTAKADDELRAHLLRGVVQGFIQ
KPFTAGELLANVQGQLKERARHKAELDELEAFRATFEAAVGIAMVAPDGHWLRVNGKLVELLALSFQDITHLDTDLARVLDGEYLGEPVWVPDYFISVVD
RKTSERRLAESEARVENAPEAIFLKEGRFAYANPDDPKEIMGR------------G-------VLEFIRDRVAERIRLLNQERRAVAQGHVRIRRIVDAS
AVPFRMGTFVRDIGERLR-----AEREIRDLARFPGENPHPVMRVDPNLVLLHANKSSGAFLDCFGAEVGRPFFVEFV----AEALRTWVMQTFEVE---
--CSGRVYAMTV-NPI--ADGGY---VNIYGMDITERKRAEREKSAFLANMSHELRTPMNGVLGMLQLL-DATPLDPEQRGYVQVAHAAGSNLTRLLGDL
LDLAKVESGRLVIREEPFDFAALAREVLAVLRPEAD-----RKGILLEAAVEGVPPSLMGDPLRIRQMLLNVVGNSVKFT-DVGRVLLQARHESGMLVIE
VRDTGIGIPESMLATIFEPFTQVEDAASRRHGGAGLGLSIVRRIMALMGGVVSMTSVEGEGTTLTLRVPAA--------------
>tr|B8DIW1|B8DIW1_DESVM Multi-sensor hybrid histidine kinase OX=883 OS=Desulfovibrio vulgaris (strain Miyazaki F / DSM 19637). GN= PE=4 SV=1
---VLVVEDNRDMIAYIVD-ILRPHHQVAVAFDGEEGLRKALDLRPDLIVCDVMMPRVDGQRMVEQLRRYADVPVLMLTAKADDELRVHLLHGAVQGYIQ
KPFTAAGLLASVHAELRDRARHKAELDESETFRATFEAAMGLALVAPDGSWLRVNGKLVELTKLRFQDITYLDSDLARLLAGEYLGEPVWVPDYFISVVQ
RKTFERRLAESEERVEHAPEAIFLKEGRFAYANPDDPKEIMGR------------G-------VLEFFRSMVVERIRQLNEERRTVPRGHVRIQRVVDAS
AVPFRLGGFVRDISDRLW-----AEREIRDLARFPGENPNPVMRVSPALVLLHANRSSGTFLECYGARVGSPFFAEVV----AESLRTWAPRTFEAQ---
--CLDRIYAMTV-NPI--ADGGY---ANIYGMDITERKNAELEKSAFLANMSHELRTPMNGVLGMLQLL-DATPLDPEQRGYVQVAHAAGSNLTRLLGDL
LDLARVESGRLTIREEPFDFNGLTQEVLAVLRPEAD-----RKGIVLEAATDGMPGALLGDPQRIRQMLLNIVGNAVKFT-DRGHVRLLARFEQGTLYLA
VEDTGIGIPSDMLGNIFEPFTQVEDAVSRRHGGAGLGLSIVRRIVDLMEGEVSMTSEEGRGTTVTLRLPVA--------------
>tr|B4VZB8|B4VZB8_9CYAN PAS fold family OX=118168 OS=Coleofasciculus chthonoplastes PCC 7420. GN=MC7420_4923 PE=4 SV=1
--KVLIVEDGYQTIKLLGEGLEIRYSFIIQQVRSCQALTRLSQEAFDLLVVHLSHADPHVFDTVTQIKQLGTLPILGLRANQDEPLTLQVIQAGTPDDQV
TENLKSYRLIRAFRH-----AIDSQQRQECQRL-NQEKYQSVIDNVKEVIFQDTHGHW-TF-----------LNRAWTEITG-FSIAESIGTSFLNGIHP
DDWQK-------GRNN--FDALIT--GVQSCRPTVRYLTKSGEIRWLE------------------------------VHARINFAADGTVSTT------
-------GTLNDITEQ-VLTQSALRISEERLMALSGSITGDIYFNPQWKAMLGYAEDEIDFQALVHSEDLSRVKAVL-KA--------YIDRLIPIVEFR
MCKTGEWKWILAGNP---------VRMTGTHRDISDRRQAEEELKQLVAGIAHEINNPIGFISGNVGFAHQYGCDLPLRTDFPNSIREGVVRVQDIVRSL
QHFSHLNE----AQMKTTDLHQGLESTLILLQNRLN------KKPNIAIEVNKQLSRLPCYPGQLNQVFINILGNAIEALDFIPQIRISTAELNSTVIIR
ISDNGLGIPAHLQEHLFEPFFTT-----KPVQGTGLGLAVSYQIIEKHKGKITCNSQMGIGTEFVIEIPIT--------------
>tr|H1NXF4|H1NXF4_9BACT PAS sensor protein OX=903818 OS=Holophaga foetida DSM 6591. GN=HolfoDRAFT_2741 PE=4 SV=1
--SVLIVEDSAEWAELIQRVLQSRQEWYTRSVGMAKARECLAERSWDLLFTDLNLPDSRGLDTLFRLRGEADTGIVVMTGMSEEALARQALRAGAQDFLV
KGAITASGITRVARY-----AFERARLDLQLRQ-SRQLLAATLDALPAFIAIDEKGRWNRY-----------DNPENPLIYA-C----TIGTDYVAICDR
DRAEN-------GAAPEVLSGILS--GGRHFTEDYSVPAFSGRS-WYE------------------------------LTVTRFTDREGRPTIV------
-------VSQVDISER-KELEAKLRTSEELFMAIIDTNGSRIYTSPSYATGLGYSQEEVAHLGLLHPEDRDRVAGAL-APL-------FHGQAANIVEYR
MHKDGRYLWFEPKSPRALIVAR----------DITERKRAEKEKVQLAAGIAHEINTPTQYIGDNATFLKDAAQELALRDEVPQQTLDGVGRVSRIVSAM
KDFSHPGG----TAIETIDLNRAIESTVTVSRNEWK------YVAEMELELDPTLPPLPCFPGELNQVLLNVIVNSAHAIAQLGLIRIQTHPTSFGVEVR
ISDTGVGIPEAIRERIFEPFFTT-----KPVKGTGQGLSQAHAIVDKHRGRIFVESEEGQGTTFIIELPTH--------------
>tr|H1NZ74|H1NZ74_9BACT PAS sensor protein OX=903818 OS=Holophaga foetida DSM 6591. GN=HolfoDRAFT_2154 PE=4 SV=1
--SILLVEDAPEDAELLLAHLEGAGLRVSHRVDPEAMSKALSNALWDLVISDYSLPRFNGMDALELLKGTGDIPFILVSGTIGEDVAVAALKAGAHDFIA
KG-----NLTRLLP------AIDRELREAESRR-KRRETEASLREMHEKLAAGEAASWITY-----------WNPMAERMFG-HPSPNALGRDLFRLVFA
EECR--------GEFERLFQGAML--GQETYGRTLELTAKTGRAILLE------------------------------ISLSTVM-LGGRWHAV------
-------AVMRDITQR-KVMEKE-RLEQLHFQTVIETIPHPIYYKDANLRFLGCNQALLDYIGLPKAELIGRTLGEC-APS-------LVNSEREVTDLA
VLREGKSLTYESKAPFFDIEGRV-AGLVGTMLDITDRKRSEMEKAQLAAGIAHEINTPTQFIGDNTIFLRDAFRDILCVTEIPDQMLDGISRVARIVGAM
KDFSHPGS----ESKMPVDLNHSIESTLIISRNEWK------YFADLETEYDPDLPLVPCFPSEFNQVILNLVINAAHAIQLKGRIRVSTCHIGNEAVIR
VEDNGTGIPEAIRQRIFEPFFTT-----KPIKGTGQGLAIARGIVDKHHGRLDLESELGRGTTFTISLPM---------------
>tr|E4NUN1|E4NUN1_HALBP PAS domain S-box OX=469382 OS=10706 / PR3). GN= PE=4 SV=1
--RVLYVNTDEDFTELVQTKLCQADIEFIHATNARTAVETVSVERIDCVVTAYSLADETGIDLTESIRQQDDLPIVLFTGQGSEEVASESTRAGITDYIT
IRTDRDELLVH---------RIQTLVQAARERRRINRFQ-RTLERTADAIYAVDTEWRIEYMNEQFEEQYRTAMETGEPISFEQYLEEPFDYW--VKVRA
FPITDERERQQ-E-L-ERNEAILQKIHDVVFVINEDN---SAAARVLERSRESLEEELSGIVSDREFLKRERDAPDDRLCAFSDAISAGQFELESLVVDG
NRYGTLNLAEL-VSSELSR---DRSLENQRLESLIEAAPLTIMEIDRDGEVLLWNRGAEQMFGWSREEVVGEPIVPKEGQSEFKQHRQQALRGERIREIQ
RTKDGERLDLLLSVAPITEAGGEVTSIIAVLDDTTEQENQLRLSNEFASVVAHDLRNPLTIASGFLEVVKETDDPT-----HYEKIESAHSRIERLIDDL
LTLARGET--LIEDTEQINLTDIATEAWGYVDT-SQ------ATLTVC-D---QAPVVAGNAGRLTQLFENLFRNAVEHG--GTDVTITVGGLDDG--FY
VEDDGQGISPERREDVFE------HGVTSNKGGTGFGLSIVADIARAHGWTVSVAEGTDGGARFVFE------------------
>tr|F7PF02|F7PF02_9EURY Multi-sensor signal transduction histidine kinase OX=1033806 OS=Halorhabdus tiamatea SARL4B. GN=HLRTI_00070, HLRTI_03688 PE=4 SV=1
--TVLHVDDEPDLAALTAEMLERDQITVETATSASEGLDLLAEGHFDCLVSDYAMPGMDGIEFLEAVRVESDLPFILYTGKGSEEVASEAITAGATDYLQ
KGGGTEDLLAN---------RIYNAVSQYRSQQKFDRIR-SLMSDLNQILVRAESRYTFAWIGDVSTAARERRVAVTENIALDRWADVATAYGF-ESIAA
VPLTLYADEPQ-P-FDADERDLLGELGDDIFAIDEQR---DRREALFANAPTPVAASPLGAGNIDAFFGFDRETPEEHERTKRVERCTREFLMHVFGLDD
APDGNYVWYTD-VSDWSER---ERE--LRAFRQAVEHTGHAVYWTDPEGSIEYVNPAFEAQTGYVAEDAIGESLLSSGEHDEYDALWETILDGETWEELV
NDADGERYVVEQTITPVTDDAGEIERFVAINTDVTEREHRQRLRDQFADVVSHDLRNPLNVASSRLELAAEECDSD-----HLEHVATAVERALSLVADL
RALAAEGV--AACETEPVDLARVAHDSWETVVT-AE------ASLTV--E---AERTISADPGRLRQLLENLFSNAVAHA--GADVAVTVGPLENG--FF
VADDGPGIPPDAVETVFE------AGHSTEADGTGFGLAIVEAIAHAHGWTVTVTDREAGGARFEFT------------------
>tr|F7PP00|F7PP00_9EURY Multi-sensor signal transduction histidine kinase OX=1033806 OS=Halorhabdus tiamatea SARL4B. GN=HLRTI_16015 PE=4 SV=1
------MNDDSAFADLVRTKLSRFDIDVRTAADAETAMEQLATIAVDCVVTSYALPAGTGIDLLEEVQAADDLPTVLFTGRGSEEVASRATRADVSDYIP
IRPNQEKLLAR---------RIETLVDAARKRARMDRFR-RTLERATDAIYAVDTDWRIEYMNEKFEERYRTAMETGEAVSFEQYVGEPFGYW--VDVRV
FPITERKERQR-E-YREEYDALLDTSGDAIFLLDVDT---TGQEPTFQFAQLSPGYEQTGLSTTRDVFGEERGA----LRSYREELMVAFWETSLVIVDD
ETVRIVGIARN-VTEQVRR---ERTLENQRLEGLIEAAPLTIMEIDADGNVLRWNKGAEEMFGWSSEEVIGEPMVPEDRQTEFEAHRQAALEGSPIREIQ
RTKDGRRLDLLLSVAPISDSDGEVTSILAVLEDITEQESRLRLSDQFASVVAHDLRNPLTVAMGFLEVAAETRDPE-----HFTKVESAHARIERLIEDL
LTLARGET--TIEDAEEIDLGAVAREAWGYVDT-SE------ATVDVA-D---DVPVVAGDPGRLSQLFENLFRNAVEHGSGGKDVTITVGKRADG--FY
VADDGVGIPPEDRESVFD------HGVTTNEGGTGFGLSIVEDIAKAHGWTVSVGESSEGGARFDFD------------------
>tr|B9LNK3|B9LNK3_HALLT Multi-sensor signal transduction histidine kinase OX=416348 OS=ACAM 34). GN= PE=4 SV=1
--RVLLVADELAVGDRAAAGIEDRRFEVTRAEDAAEGLSVVDRKPVDCVVSGYDLPGMDGVEFLRTVRERVDLPFVLFTARGSEAIASEAVAAGVDEYLP
VGGDNDATLAS---------RVDYAVSRSHTER---RVT-EHLDRMTDAFCGIDESWRLTYLNKRFEEQFRDAMATGEPTAFEHFAGPDLDL----AIDA
YPVTEEKERKR-E-LRERLRLAVEGADAGVWNIRTDD---ERWASMLGYDRSEIAFDLAGWEELAVWFSGATEQ----FRKWIRDRGRV------RNDEG
EPVRAVGIHID-VTEEKKR---ERD--LKRYRRLVDELPDSVAVYDADGRFSVVNDRIVDVYDSTPEELIGRPLVARLRERSEDDPFAALVAGD------
RTLSGTELDFPVRSDAIVDIDGEFDGVLGIARDVTEKRRRQRLEDEFASIVSHDLRNPLNVLSGYLRLARETGNES-----YFERCDTALDEMERLIADV
LTLARQGD--AVGSVDPVSLGELATDAFGSIDD-AD------DSVEVAVE---TKGDVLADPGRLKRLLQNLFRNAAEHG--GDRVV--VGDLSDG--FY
VADNGPGIPENRRDEVFE------SGHTTSESGTGFGLAIVERIAEAHGWEVTLTAGADGGARFEFT------------------
>tr|E8WLI5|E8WLI5_GEOS8 Signal transduction histidine kinase, nitrogen specific, NtrB OX=443143 OS=Geobacter sp. (strain M18). GN= PE=4 SV=1
-REILIVEDSATQAEQVRYSLEKHGFAVRTAANGVEALSLMQQKPPDIIVSDVVMPEMDGYEFCRRVKEYKQIPVILLTSLSDPRDVLRGLECGADNFIV
KPYDERYLLSRLNAHLRQVDTIEIVLAGEKHFIKSDRISILNLLL-SSYEIAIMRNSELVRVRDEMLLLN------------ESLEEKVAE-------RT
FAIRRKEVEEALKESEERHRVCIAPPGTVYLWNRYTSGEALGKS-VPD-----------LIIPAIALLLRDGSGPVGKSTELTRKKSGEEFPAELSLAAR
GEWQAIGIVRDITAR--KQAEQELQKVKNYLSDIIDSMPSVLIGFCANEVVTQWNREAARITGIPASEAIGRQVGAL--IPEFYSWIETLRSQARTRRSA
LTRGGERSFYDL---ILYRLSDSEQGAVVRIEDVTERTHIQEMMVGLAAGMAHEINNPLGIISQAAQNIERRAASEQQVPQFVDSIRQAASRAAKIVTNM
LQFSRQAP----MAKQPASLERLIEQAVEDYDLKKK---YDFRAVEIVKEYQPDMPEVPVVAVEIEQVILNLVRNAAQATPERPRITFRLRTEGKYAVLE
VEDCGPGMDEKVMRRVFEPFFTTKE----PGVGTGLGLSVSYMIVTAHKGLLEVASAPGTGACFTIRLPLK--------------
>tr|A1ATD5|A1ATD5_PELPD Multi-sensor hybrid histidine kinase OX=338966 OS=Pelobacter propionicus (strain DSM 2379). GN= PE=4 SV=1
-NRILIVEDELIIARGIQKRLQGMGYDVIDIPSGEEAIQSATENPPDLVLMDINLQGMDGIQAAESIRSRLDLPVIYLTAYTDERAKVT----EPFGYIV
KPFQDHTLQSAIESRLKKSESIGDAVVTTDVS-GLVS------YVNPVAEELIGLTQEVALGRPLEELFRYLMTESGKTVPIEALTPISGGEDILGMVLM
LDVTAQRRT---EQALRRSERILTLKNQNIFLATPDEQMFSQVLSVIRDAIDCAHALFGCLIPFSGLWGRALREQVSCCGDGPFSVPQGNFLAIPVVYGE
SPILQARLERDRLERKRGEAAEALATEKERLAVTLRSIGDGVITTDTSGMVVLLNRAAEEMTGWTQEEAAGKPFQDVFRIINE-KSRECVEQVLADGNHT
LLDGGERVIADSGAPIRDRQSR-LVGVVLVFRDITEKKKMEEERKLLAGGIAHDFNNLLTSILGNISLMQVGEGDR-LR-RNLDEAEKASLRAKDLTQQL
LTFSRGGA-PVRK---TVSLTAIIRDSAT-FT-------LSGSRTTCRFQIPDDLYPVDVDEGQFSQVINNLVLNADQAMPAGGEIEIVCANAGAYVRIS
VRDRGEGIPEELVPRIFDPYFTTKKE------GKGLGLATVYSIIRNHDGHISVSSSPGQGTAFTIHLPA---------------
>tr|F9ZG61|F9ZG61_9PROT Multi-sensor signal transduction histidine kinase OX=153948 OS=Nitrosomonas sp. AL212. GN=NAL212_1046 PE=4 SV=1
-KLILIVEDNIDMNQFIADTL-REHYRVSCAYNGQQGLEQALETIPDVILCDAMMPVMGGYQMILALRQYPHVPVIMLTARVDEALRLELLRLGVQEYLN
KPFVVDELRARINRQLRESEVRF-QVIFEQAAVGIGIVSL------EGRWVNQKFCDLVGYRHDELTFLTDLDADLSYV-QRTLAGEIS-TYSYINSLLW
VSLTVSLVRKIIQDIQSRKEIEANIANFGHWRWDLDTNTQIWSE---EIFHIFG---RDLDLPVAQYFTAELSAAVEKCREGVAEVVQPDGSHHWVVARG
EAIRNAEDQIISLHGTVQDIEVALQQSQEQLKLFIEYAPAALAMFDRGMHYLACSQRWRNDYSLGDRNLLGLSHYDVFPNIEWKAIHRKCLAGEVIRSER
YVVDGTWLRWEV-RPW--LTGNIIGGIVIFTEDITQQKQAETSLESFVYSVSHDLKAPLRGVEGYSRLLEEDYFDD-EGRLFISNIRTGVTHMNELINDL
LAYSRMERCKLQ--SHELDLTLLIHQALAEYNEE-----ITLHAIEIVADFPS--FKVYGDREGLVLTLRNLLGNAIKFSQPHPRIEFGACRNKDHVILW
IRDNGIGFDMKYNSRIFEIFERLHR--LEDYPGTGIGLALVKKAMQRMGGRVWAQSSPGEGATFSIELPAA--------------
>tr|F9MV54|F9MV54_9FIRM Response regulator receiver domain protein OX=879308 OS=Peptoniphilus sp. oral taxon 375 str. F0436. GN=HMPREF9130_1163 PE=4 SV=1
MYKIFIVEDDPSIFSSIKFHLEVYGVD-----DFSRVLEDFERVDPHLLVMDIGLPFKNGYYWTEEIRKKSKLPILFLSSMGEDLDQVMAMDLGADDFVV
KPVSLALLLAKIKAQLRRAYEL--QVQD-------QVLEDGELLLNLDTMQVTYQGRMESLSKNEFLILRSCLQAQGRVIHREDLMNDLWQSDLYIDDNT
LTVNVARLRKTLKSWAWKTISIQKREW-----------VIMGPLKNKDLLVLWGLTGI-FFFSYIYVQSGRLADSL--------------YGLGIYSLSW
GGYF-----FYAYQR-DKKLAEKIRQE-----GL--------------------------------EDYAGQGLLEE-------ALVEEIHKVEKR----
-NLD--------------QENQF-------LQD-------REKRANYLLRWSHQIKIPMTAILAWLDA---QGIQD-KNPRFQ------VFKIQEYIDHI
LSYQRLQGRDTDYVFQWLPLKDPLQKALRTYAALFI-----HKGLRVQMDLPE--VEVLSDAKWLLFFTKQWLSNVVKYT-HTGGLTISFQEG----KLI
FQDTGIGIAPEDLPRVTDMGYTGFSGRKFD-QSTGIGLYLMKEVAENLNLVMTLESQVGQGTRLILSFPK---------------
>tr|K9TGJ6|K9TGJ6_9CYAN PAS domain S-box OX=56110 OS=Oscillatoria acuminata PCC 6304. GN=Oscil6304_1996 PE=4 SV=1
---VLLIDDQPIIGEAVSRMLVDE-EDIIFHQDPLDGVRQATEISPTVILQDLVMPDVDGLLLLRFFRATRDIPMIVLSVKEEAKLKAEAFAAGANDYLV
KLPDPIELLARIRYHSQAY--------------------ISRLQR-DEAYQA---LQESELRLRG------VLENMPVMLT---------AFDVEGNIIV
WN------REC-------------ERVTG-----YSASEVIGNPQAKHLFSDQS-LESG-ISTLSAPSTSPIVSPVPSVRDAVNKARNHGRAREWQITCK
DGLLK-TVAWSNISSRFPRKQAELAQEQ-EYQQLIKNAPIAMAMFDTEMRFLAYSNQWLTDHNLVSQSLLGCNYYDIFPDIK-EDWKEIHQQGLQGTEDK
WEADGSYFRWAVVNPLNSIEDGEIGGLIMVADRVDELIQTEHAKSQFLANMSHEIRTPMHGVLGIAGLMLHTELTP-KQQEYAETIRISAKHLLGLINDI
LDFSKLEAGEMHLENLDFNLYECLQDVVNLFKPQAE-----DQGLTLKLQFQENLPFVRGDPSRLRQILLNLVSNAIKFT-PSGSISVEAKLSKTRVYFQ
VTDTGIGIPPEAQAKLFQSFSQVDPSTSRQYGGTGLGLAICEQLVSMMQGEIGVTSEVNQGSTFWFTLQF---------------
>tr|B8GIL9|B8GIL9_METPE PAS/PAC sensor hybrid histidine kinase OX=521011 OS=Methanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c). GN= PE=4 SV=1
--RVLLVEDNPGDARLIREEIHTDRYEVVHVERLEYALLHLNNEKFDTILLDLNLPDAYGLSTLVKIRKAPHVPVIVVSGLGDEEMAIHALREGAYTYLV
KGQMSGHLLDRSIRYSIERERMEQIVQLQR---------------------AREYAENIVDTIRES--LIVLDNRLRIVSTPEDLADQEWNIPQFL----
------ALLEKILHH------------------SFQY-------EGLELDHEFPALGRRVMLL-NARWVYE---------------ERGDTDRIL-----
-------LAMEDITER-KRAEEALADEKERLAVTLWNIGEGVIVTDVGGSVGMMNRVAESLTGWTASEAVGLPIDQV------YQVINAVLKKEETTDSS
LLIGGIERPLGDSVAAVRDKDGKIIGVVIVFRDITAARRMEEERLELAGGIAHDFNNALTAIEGNIVVA--KAHLKPEEKAYERLSEAEAHRARDLTRQL
LTFSRGGKPIK----RQLRLNDLLIDVSFALSGSAV-----RKKFSIAED----LWPVEADEGQIRQVINNLVINADQAMPDGGILDVSLAKAGNYVRIA
VKDHGIGIPKEFLSKIYEPYFTT------KQKGSGLGLTVAYSILRNHGGSLIVDSVTGGGSTFTLYIPAS--------------
>tr|D3RTB5|D3RTB5_ALLVD Multi-sensor hybrid histidine kinase OX=572477 OS=(Chromatium vinosum). GN= PE=4 SV=1
--RLLIVEDSADDAGLLVHTLKEAGYQVETVEQLREAWLI---GPWDIIISDDRLPGLDDPKALARMRRGPDVPLIVLLDAADEDIGVRAMKAGANDYIL
KGHVEREL----QEANRRRQTLVTKVQFRALLDSVQD----------AIMVVDEHGRIAIFGYAMREM---LGQGIGFLLP----------GDGY-----
---------ERLKCNPVQPGD-L--TGTQVYERRYEGRRHDGRMLTLEASS-S------CA---SVFGSRTYTFILRDITEQ------------------
----------------Q-QAEAALRESERRYRELVQSASSAIIRWTRDGTLTFFNEYAERFFGWSAEEVVGKCRIDILVPDQTSDLRGLIEAHPEDYRSN
INEDGRRVWMSWTNQAIRDAHGAVSEILSVGSDVTARLQLAQARSEFLANMSHEIRTPMNAVLGLAYLLERQLPEE-ACD-LARKIYHSGQSLLGIINDI
LDVSKIESGKILIEQTRFQLSQVLDNLATIMTT-AAR----GKDLALAIVPPRDDWPLLGDPLRLGQILINLTNNAIKFT-DSGVVEVRITPVALVMRFT
VRDTGIGIDAETQARLFQPFMQADASTTRRFGGSGLGLMISRQLVELMGGRLGVESAPGVGSTFWFEVPLG--------------
>tr|G2E1S7|G2E1S7_9GAMM Multi-sensor hybrid histidine kinase OX=765913 OS=Thiorhodococcus drewsii AZ1. GN=ThidrDRAFT_2240 PE=4 SV=1
--RLLLIEDSSDDELLLLHALQEAGYEVKTAEGLHEALQM---GIWDVVISDYRLPSFDGLSALEMVRKRRDTPFLFVSGTVMDDVGVAAMRGGANDYLM
KSNLDREL----KEAANRRQTLVTKVQYRAILDSTLD----------AILVAEESGYITAFGYSAAEI---LGQHIGILLP----------GDAF-----
---------ERIKCTPAKPDN------ARVYDSHYDGRHQDGHDVPIEASC-A------KA---LSEGHRIYTIVIRDISQR------------------
----------------L-AAERALRDSEERLRLLMDNIRDAIIMLDTKGRVTTWNQGAANLTGYEAEEAVGR-PLSLFYPPEDVKPRQLLKD--EGRSAE
EGWDGSRFYAEVILTAARDASQELFGVTKITRDITEHRALARSKSDFLTNMSHEIRTPMNAVLGLGYMLEQQLPED-ALD-LAHKINQSGKALLGIINDI
LDFSKIESGRIEIEHAPFALSGVLDNLATIMTT-ADQ----EQDLELVITP--DDLTLIGDALRLGQVLINLSSNAIKFT-RSGLVEVHIETLDVRLKFS
VIDTGIGIDEAAQTRLFQPFSQADASTTRRFGGSGLGLAICRRLVDLMGGHIGVHSALDEGSTFWFEIAFD--------------
>tr|D4H210|D4H210_DENA2 Multi-sensor signal transduction histidine kinase OX=522772 OS=Denitrovibrio acetiphilus (strain DSM 12809 / N2460). GN= PE=4 SV=1
MKKILIVEDEIIIGLDVARRLGKLGYQVTTATRPDQALESIKIDKPDLIMMDINLKDIDGVELAAMIRKDNDIPVIYMSYSDSMIDRAIQTE--PYGYII
KPYTDGMLIASLRTAFARKEL-------ENKNRSQHEMLQGVMDNISDSIVLIRGSGEIIRTNSRFSELVGADNLVGK----------------------
----------NIEDVLGGSPDIETLHNIGSSRSEMFTAKIGG----AEKSILIH--------TSDFVWEGRKSTLL-TITDLT-----------------
-EIIAVR---SALSDAEQRFTKI----------FRKKMIPAVLVSCEGMRLFEMNDAFAQLYKVSQDVEADISISEYIGSEALKAVEQSMDADKSFRVDM
IRKEGEFRGKRVEFD---S-A---SFFLFDVHDVTEQVRISEMERELVSGVAHEINNPNNFI-MFNSSLLVDFWSDKTLAEFMHGIINGSERIKNIVQDL
KGFAKTESSGY---SERLNIENTLRTSVRILEHQIS-----KTTGNFIMDIAPGLPDVNGNEQKLEQVFINILMNALEAV-ASGDVEVKCYPSAGKVVVD
FTDKGVGIPSDHLDRITEPFFTT----RQNCGGTGLGLSIAYAIIKEHKGVIDISSTPGEGTCVRIQLP----------------
>tr|K9XGM7|K9XGM7_9CHRO Multi-sensor signal transduction histidine kinase OX=1173026 OS=Gloeocapsa sp. PCC 7428. GN=Glo7428_2700 PE=4 SV=1
---VLIVDDEKFTRLQLRLAMEQVGYQVVETSNGEEALVAYTQVQPDIILLDALMPAMDGFTCSRALQGGDRTPILMITALEDQESVDRAFAAGATDYIT
KPIHWAVLRQRVYRLLRATEKLRARVSEERAHMGTWDWDLLNNKISYSATAAANMGVEVA------------------VDTYESFLESVHPED-------
-----RQVLEQIINTAGSIHWI-AARGQVYYNETGT---AI--------------RMTGINID---ITDRKHEAALQQ----------QTLRSQLFADIT
---FKIRR-----SLHIEEILQTTVTEVQRLL-----LCDRVVSSDGSGKVVKVVPGLTAILGRNLKQYLDKYIRGHIGVADIYNYIDFL-KQFQVVIKE
LLICYKPRQWHFEVELLQQLSD-QIGIAQLLEDETRQRRVNAELQQFASVASHDLQEPLRKIQAFGNRLYGDVLND-QGRDYLDRMQNAAQRMQALIDDL
LTLSRIATRAQ--PFVPVNLTQVAQEVLSDLEILIQQ-T--NGRVM-L----CELPTIDADALQMRQLLQNLIGNALKFHQQDQVPIVKIYSQAEDWEII
IEDNGIGFNEKYLDRIFNVFQRL-HSRSD-YEGTGMGLAICRKIAERHGGRITATSKPMQGAKFIVTLPIK--------------
>tr|I4C9H7|I4C9H7_DESTA PAS domain S-box OX=706587 OS=Desulfomonile tiedjei (strain ATCC 49306 / DSM 6799 / DCB-1). GN= PE=4 SV=1
--TILFVDN--VIEDIILMEAFESDYTCCFATSGGTALEVVRSRKPDLILLDTTMPDMDGYEICRRLKTTRDIPVLFVYTMHEMGDETRGLELGAADYIA
KPVNLSLVKAKIETHLKLREAMGNRILSA-CPVGI--VCVRNRVWVSRTFVEMGYQDESDFTGKDVEMIY---------ASREEFGKIFYNPGTAGLISD
VDVAFRRKDGSIFEGLSDPETIATRKKSEKALKEAD---------TFLS-----SLINAIPVPLGFNRAYQYGKTIDELVKSVFDIAPKEYHAKLELFRN
PALGIVKATFNDSRGNLKKAENALKESDAFLSSLMNAIPVPIFYKDTDGRYLGFNKAFGELYSKKLEDLVGKSVFDLFPRE-QAKVYELFVKVYESVLSD
TRGMVHNVVFH-KASFTDSQDN-VRGLIGAILNITERKKAEQLRSEFLAKMSHEIRTPMNAIIGFAGLALKTDLTS-KQRDYLSKIDSSAKTLLGIINDI
LDFSKIEAGKLDL--ESIDFDEVINGIANMVSVKAS-----EKDLELISQIGSNVPALIGDPLRLGQVLVNLVNNAVKFT-EHGHILIKVENTDCVLKFS
VTDTGIGMTPDQMTRLFAAFSQADTSVTRKFGGTGLGLTISKHLVEMMGGQISVESELGRGSTFSFSIEF---------------
>tr|Q7MA84|Q7MA84_WOLSU SENSOR KINASE OF TWO-COMPONENT REGULATORY SYSTEM OX=273121 OS=11488 / FDC 602W) (Vibrio succinogenes). GN= PE=4 SV=1
--TILVVDDSRAIREMCKSVFEIRNYSIALASSGKEALELIESERIDLVILDLFLPDVHGLEILYKIRENSQLPVIALSSTLDHIAKV--LKHGANDFIN
KPFSIEQIILKA------ANLIKDAHAERELAERL--LEVEELRRLDDAQRIAKMGSEEDLSQKN------------TWWSRG-IYE-LLGYTPFEVEPR
AELFFQHIKESQEQYISEDYEILTKKGEGRWLNSSVIRDEKGTLLKAQGAILDV------------TENKRLRDELLRFNIE------------------
------------LEKRVRHEVMGKLRLERQFRQLFENSYDAILLIDRQRRIIDCNQTAQKLLGYSKEELRLLPPYRLLRAMS-ARSIKPIFQDILAKRRE
ITLSGEQLLGQLSFNTLQEEDS--NLLLCSFRNLTEQYLLKEEKGEMIGSIAHQWRQPINALAVKIQDI-ELAYENELTPSYVDHFVHSSMFMSHTIDDF
RNFFRPSKATS-----TFKVLEEIQKSIAMVQNQAR---LSQISCLLHSELPK-DFTITGYQNELKQVLLNLLKNAIDSVEEERKIDLFLSLKEPFLEIQ
IQDTGVGIPQGIKEKIFDPYFTT-----KEQKGTGIGLYMSKIIIENMEGKISVINQPGSGALFTLLIPIE--------------
>tr|E8WTF4|E8WTF4_GEOS8 Multi-sensor hybrid histidine kinase OX=443143 OS=Geobacter sp. (strain M18). GN= PE=4 SV=1
MATIYIVDDRELNRQYLITLLGYFGHQLEEAGDGCELLALVERQVPDLIILDIVMPNMDGTEVVERLRHHASIPVIFYTATYRNQEANIARTCGVRWVLS
KPSEPRLILETVAKAPPPVPELEAPV--SSALSGKWDLETRMVALTNDAMRQAPSGETVPRGAGSEQLIQM----------QAMVLKLVALVEDAGAVRE
PRLVFCRAAQDILTTKYAGVGILKEEGPGFRH--FAMKGNGGSASSWPWSAPPGASFLAVPIVYGWLYCADGRDGFGMDDERLALTIASQLSLI------
FENLEFSEEH---QMHAGRLRQELEERKAVEEALRASANDGLWDWNLKTGELYLSPRWKSMLGYADEEIANSDWKSRLHPDDLEPVTNRLSDGDQGSKFE
VEFKGHYVDILSGFLVFGDDGEALRMVG-THVDVTERKKLEEMQMEAVGGVAHDFNNILSAIIGYSELTLRKVGADEEARHYVDEILAASHRAATLTRSL
LAFSRKQP----VSLAVIDLNEVVGGFQSFLSRLIK------EDIELKVACGTERLPVLADRGQVEQVLMNLVANARDAMPRGGSLVVTTRKPGQYAVLT
VADDGVGMDKQTVSRIFDPFFTT-----KEQEGTGLGLSMAYGIVKKHDGFINVYSETGNGTVFNIYLPV---------------
>tr|D7A030|D7A030_STAND Multi-sensor hybrid histidine kinase OX=639283 OS=NBRC 12443 / NCIB 9113). GN= PE=4 SV=1
NPRILIAEDSPTQAAQIVHFLSRRGYAVNAARNGEEAYELAVATQPDILISDIVMPGMDGYELCRRLKATEDTPVILVTSLSQPQDVA-GLEAGADNFII
KPYDEEVLSSRITYLLRRAERSGDQL--EVDFGGRHHITARKQQIL-DLLISTAQAVHLALDQGRQELSQS----------YEV---LHALYDGLNRCRT
PDVAMTTVSRSIGMPGVRDAWIYLRDDDGLRL--TAERHTGRNAQPDPF--PPSAHHASMRLRFGFL---NGSEPAGEVALRTLAAIASQVSIA------
LEHTDLENEV---RKRTQRLVEEVEERRQATETITANAQLSLTTWNRTATEIF----------RADSALVSGNWFTLFAPTRLHDVMGTLQSGGEISSLE
VDAAPRSLHIAGPLI---DTGGVFRGAV-LAIDITAIKQVKEHQMEAVGGIAHDFNNLLTTIIGNLDLALKSTEACVQQRPYLDTAMRASLRGSELAKKL
LAFARKQP----LEPQALEPSAIMDELRLLLDGRLG------PHIGMMLTVAPEVPMVYADPVQLESALMNLAINARDAMPAGGEL-----RRAAVE-FT
VRDTGIGIPPEQLDRIFEPFFTT-----KEMKGTGLGLAMVYGFASQSGGYLTVESEVGIGTTFRLGLPA---------------
>tr|A7H8G9|A7H8G9_ANADF Multi-sensor signal transduction histidine kinase OX=404589 OS=Anaeromyxobacter sp. (strain Fw109-5). GN= PE=4 SV=1
--HILFVEDDAGTRYAVNRVLANAGFRVSVAATGAQALALARSARPDLVLLDVQLPDAIGFDVCRELKATSALPVVFLSARRADEDLVRGLEGGADLYLT
HPVEPHVLVAALNALLRVR------LAEARLRRFVDSNMIGV----------AEFDAESVLTDGNDELLRILG------LTREDIAAVTWP-----EI--
VPSEWQAQQASLEGRPRREG------MVGPLEKEYQRKDGS-RV-----SVLIG----AAALPVAFVLDLSERKRAERER--EEALARAEAAMGFLLSAT
SAPGEIAAALRRLATLCAREIA------------------DWCIVDREGAVRMAVAAADPARAVVEARAPGRQQLELVDDPEAL----------EPARDG
-RHRQALLTLRVVFPL--VQGGHVLGALTMVRALEELSRSLRAREQTLAEVSHDLRNPLSSIILAAAQLERSAGRS-ELPDLVASIRRAGDRMNHLVQDL
LDLARAENGRLELDVGEHSARELVDDAVESIAPVVR-----ERELRVRAA--VEPLLVRCDRERVHRVLANLLSNAVKVSPRKGTVELTARQRERAVLFT
VADEGPGISLDEQRHMFEHYWRGRES---GAQGVGIGLSIVKTLVERHGGKVWVDSVPGAGARFSFTLPRA--------------
>tr|Q5UY83|Q5UY83_HALMA HTR-like protein OX=272569 OS=B-1809) (Halobacterium marismortui). GN= PE=4 SV=1
--RVLHVDDNPDLVDVTATVLEHEDLCVETATSVDAAMERLSVERFDCIVSDYDMPDQNGIEFLEAVREGGDLPFILYTGKGSEEIASDAISAGVTDYLQ
KGSGTEQLLNRVDASTRRLESLISSL------PGMAYLTPGQMETVEGEI-ESLTGYTAADEETAWDDVLHPED-CDR--IWETVQDALFEPDILGFI--
TDMTDLRERERLERYKRMPES-A---------CIYDTEGRFDLVNQYL------ASFYGTTRDLGESSSLPKIRSEYEG-DPYQDLIDGERDELHGEVSG
YEVLEYRLVEGVVTEQRKHEMRQRSILKAQQEAVID----GILVVDEDDTIVSYNERFVDMWDIPRDIVERGLEWAMEQVADVEALYE----DPETARDE
LELDGRVFD-RYTAPVVAEDG-TRFGRLWAFRDITDKRELAREREEFIRVVSHDLQNPLQVARSRLMLAHEECD-----SAHLDSLDNALQRMNDIADDV
LRLAREG--VDIGVTEPVDLREMSDAAWTIVAD-GDE------AAELRYAADE---NVEADSDRLSGLFENLFGNAIEHG--GPGVTVSVGLLDDRTGFY
VSDDGPGIPIDKGEKVFEAGYST------AEDGTGFGLRIARQIAEVHGWEIHVTDSEDGGARFEITG-----------------
>tr|F8D3T2|F8D3T2_HALXS Multi-sensor signal transduction histidine kinase OX=797210 OS=Halopiger xanaduensis (strain DSM 18323 / JCM 14033 / SH-6). GN= PE=4 SV=1
--SVLYVDDDPDLRSLVATFLERRDLSVATATSAGAALDRLTA-DVDCIVSDYELPDTDGIEFLEAVRGEPDLPFILFTAGGSEAVASDAISAGVTDYLR
KGTGTEQALDRVEASRRHHTAIETAQ------EGISIVADGRFQYVNDAY-AGLYGYDPEELGEHWELLYPDSE-VEF--VRSELVPAVWHSELICTV--
RDVSDREARERLTRLHALIEA-T---------TVDAADDILEFPLNGIHRYNSSRELLGEPPVTGLAWERGEAKVYGDV-REAEGVLNPDTPIRSEDEHS
TECDAFDDFAKLLLDRTAHA-RKLELLQERTQTLMNTSATADVAVTAAREILGADLSTFHGFDTVHEVFDSTSVWEVFDDGDTNEYPEF---VDETARSA
ILHIADVVT-STTPRAFSQTD-AKLTDILALERVDRTAELEAERERFASIVSHDLRNPLQVAEGSLELAREGYDGDNTADDHLDDARWALERMNGLIEEL
LTLARDG--ERIDDPEPVDLAALSETCWRSVAT-AE--------ATLVTRVDR---RIRADRSRLEQLLENLFRNAVEHG--GDGVTVTVGDLEDEAGFY
VEDDGPGIPDDDRARIFESGYST------SADGTGFGLSIVHEIVAAHDWEIAVTEGTGGGTRFEITG-----------------
>tr|C7NQQ8|C7NQQ8_HALUD Multi-sensor signal transduction histidine kinase OX=519442 OS=Halorhabdus utahensis (strain DSM 12940 / JCM 11049 / AX-2). GN= PE=4 SV=1
--RILCVDDERDFLELTATFLEREQFTVETAPSATAGLDRLGDGAFDCVVSDYEMPGANGIEFLETVRESPDLPFILFTGRGSEDIASDAISSGVTDYLQ
KTTGSDQVLNRVEQTTRLREVIDAMP------HLVYIVEDGTYLLANQAL-ADFHETTVEAEGATVSEILGDQA-AEQ--FRADLTDVLKRRAVLGIA--
VDRTERVDRERHEETDVLFDT-L---------PVHESRQVLSVNQRLLDLFESPSAIVGTDSALAKMRDVESSRSLHQL-DESPTAPESNTDRQLDLGDH
YQTVDFPDLWVY-SEHTKRNADRLEGLHDATRDLIRADTVGTLVADSVSSILDHPSNVVRF-SDARAELGDRFPGDVYRTGDFEACDRG---VDNGHRSA
LYVIGDSIG-NTEQGAFGRVD-RMLATVLALDRLTGERTLKRERAEFGRVVSHDLRNPLEVARTRCQLAIEDCD-----HSHLDAVERAHERMETLIDDL
LVLAQNG--ATIAEPEWLDFATLVDRCWTTVRT-AD--------ATLENEADG---RICGDENRLRQLLENLFRNAVSHG--GETVCVRIETTDC--GFC
VADDGPGIPVADRERVFDVGYST------RDAGTGFGLSIVSQVADAHGWDVTVTESDRGGARFEFTD-----------------
>tr|Q5V3S3|Q5V3S3_HALMA HTR-like protein OX=272569 OS=B-1809) (Halobacterium marismortui). GN= PE=4 SV=1
--CILHVDDEPGFADMAATFLEREDVDVQTATSATAGLEILADNDIDCVVSDYDMPERNGIQFLEAVREEGSLPFILYTGKGSEEIASDAISAGVTDYLQ
KESGTDQVLNRVESQNRQLDAIETAQ------EGISILEDGEFIFVNEAY-ADLYGYEPEERGRHWELLYRDED-IPR--IYDDILPTVWTGELVCTV--
RDISDQRDGEQLSRIKR--------------------EAPVGITITGPKQERQFLELTGYTESVGRNCRQGEETEAEPV-DAMRAAIDADEPVSVERKDQ
VSIAPVRDVVNYVTERKEHE-RRLKALSESVQDLLQADEVAEIGVETARTVLGLEANTIHLYDGIYDLLEDLIAWRVYESGDVHADPDI--YNPDTIKSE
LYLLGRLAG-SGTNAAFDQRD-VILGEILALKQVEGERDLEQDREAFTSVVSHDLRNPLNVAQGRLQLAREQYE-----SEHLAAVEQAHERMDTLITDL
LTLAQDG--ETVTDRESVALASLAENCWTTVET-AD--------ATLVTDIDR---TVLANESRLKQLFENLVRNAVEHA--GADVTVTVGALDD--GFY
VADDGPGIPEDERETVFEAGYST------STEGTGFGLSIARKVAAAHDWEISVRDSADGGTRFEITG-----------------
>tr|Q8TRB3|Q8TRB3_METAC Sensory transduction histidine kinase OX=188937 OS=C2A). GN= PE=4 SV=1
-VQILLFEDNPGDANLIEELLEDADFPFELKSTLNEGLVLLKEHQFDVILSDLRLPDSDGIDTFLEINKRSRTPIIILTGMNDEKIGIEAVKKGAQDYLV
KGQADGRLLKRSIRYSIERKKAEE---KVQSLANIVESSNDGIVTE------SLDGIIVSWNKGAEQIYGYSAE---EILGK-HMSILLVGE--------
---TVERIK--------------KGEKIYHYETSMLRKDGMEKVSITLSP--------------------------------------------VFGGSE
NAISIIARDI----TKRKKAEEELLKSEERVQSYLQNFRGIGTQLDENFIPIFLHGAVAELTGYTKEVLSGLHWREIVEPEDLTELVQKMKATPNAFKHE
YRKDGEIRWIHEIIQNIS-EEN-KELYQGF-VDITERKKAEEMKESRIKEIHHRIKNNLQVISSLL-DLQAEKFEDPIRQAF-----RESQRSMALIHEE
L----YESG----EIGTLNFAAYMQKLVENIFECYN---IGDHKAHLHLEI--EETFLDMDTAVPLGIIVNLFSNSLKHARDEGIVKIRLCREENNLILT
ISDNGVGMPETV-----------DME-----SPCTLGLQLVTILVDQLDGEIELK--RDSGTEFIIKIAV---------------
>tr|K6TLK6|K6TLK6_9EURY PAS domain S-box OX=1220534 OS=Methanobacterium sp. Maddingley MBC34. GN=B655_1705 PE=4 SV=1
-VRILILEDVPLDLELMETELKRDGISFVSRCEEEEFRREIIDFQPEIILADHSLPHFDGISAMYIAQDIPETPFIFVSGQMGEEFAVEMLKKGATDYVL
KHNLSKRALKEAEYHRNKKEAEEK---NEKKYRALFELSPDYVVVL------DPDGRVLDINHRVEEASEISRD---DIVGK-EVNELIDEN--------
---SIFEFL--------------TSNQIGEIKVEGDSGIEY--IEVHHAPI-------------------------------------------IREGKT
FAIQIIGRDI----TQRKKAENALIESKKHLHAIINASPFAIVDLYPDGRVKLWNPAAESIFGWKKTEVLG-KPLPFLNENKLIKYISNVLSGEFKSDLE
LENDGELYTMMATAPLLNVDNN-IQGVMATFADISDMIMAEKEKEVLLREIHHRVKNNLQIISSLM-SLQSEYTQEPTLKMF-----QESKRSMALIHEK
L----YQSE----DMAHINFGEYLKSLVEMLSSFHK---EKRNDVDVCLNC--DNVFLEIDTAISMGLIVNLVSNCFKHAETKGLIEISLSTVPEGYLLE
VADDGVGLPDNF-----------DLE-----NTNSLGLLIVQTLTMQLKGSLEIE--KGNGAIFKLVFNE---------------
>tr|K6U0E8|K6U0E8_9EURY PAS domain S-box OX=1220534 OS=Methanobacterium sp. Maddingley MBC34. GN=B655_1396 PE=4 SV=1
-IKVLILEDVPLDAELIERELRKEGFDFTSHRHEDEYRKKVEEWQPHIILADHSLPQFDGVSALHIAQEKSHTPFIFVSGKIGEEFAVEMLKKGATDYVL
KHNLSRRALTEAQEHLEKKIAQEE---SEKKYRALFEKTKNPILVF------TEDGTFTDFNQAAVDFLETEPV---QLLKH-KIHHFLAPK--------
---AASLDM--------------KDWSTGELPLEINDELKI--LELTITP--------------------------------------------VKLGET
NIIFGTGRDL----TQQKRMENALKESEEKYRLLVENQTDMVVKFDPEGEVLFASPSYCEVLGRTEESILGSNFLPLVHQEDQKKTLEKLRRPPYVVFLE
HRMNGWRWIAWADKAIMNDKGE-LEAFVGVGRDITERKLAEDEKELLLREIHHRVKNNLQIISTLL-SLQSSQIEDQVIDLY-----RESQRSIALIHEN
L----YQSE----DLTNINFANYVQNLINDLFHSYG---VDPDKIQINMHI--KDVKMGIETAIPCGLIINLISNTLKHAQGEGKIYLELRKDDGKFLLI
VQDNGKPFPSEF-----------KFD-----DTDTLGMKLISSLVNQLDGKITLI--KDNKE-FKIDFEE---------------
>tr|K2RQI8|K2RQI8_METFO Sensory transduction regulatory protein OX=1204725 OS=Methanobacterium formicicum DSM 3637. GN=A994_10394 PE=4 SV=1
-IKVLILEDVPLDAELIERELRKEGFDFVSHRSEDEYVKEVEKWQPNIILADHSLPQFDGVSALHIAQEKSHIPFIFVSGKIGEEFAVEMLKKGATDYVL
KHNLSRRALKEAQEHLEKKKAQEE---SEKKYRALFEKTTNPILVF------NDEGVFINFNQAAVDFLETKPS---QILKH-KIYQFIAPE--------
---SEPFDI--------------KEWSTGELPLKINDELKI--LELTITP--------------------------------------------VKLGNS
NIIFGTGRDL----TKQKQMENALKESEEKYRLLVENQTDMVVKFDPDGKVLFASPSYCEVLGRTEDSIIGSNFLPMVHQEEQEKTLGKLRRPPYVVFLE
HRMNGWRWIAWADKAIMDDEGN-LEAFVGVGRDITERKLAEDEKELLLREIHHRVKNNLQIISTLL-SLQSAQIDDQVIDLY-----RESQRSIALIHEN
L----YQSD----DLTNIKFATYVKNLIDDLFNSYG---VDPEKIQINMQI--KDIIISIETAIPIGLIINLISNTLKHAQGKGEIYLELAKNRDKYQLI
VRDNGKPFPDNI-----------KLN-----ETDTLGMKLISNLVNQLDGTITLN--KDNKE-FTIEFEE---------------
>tr|O26546|O26546_METTH Sensory transduction regulatory protein OX=187420 OS=thermoautotrophicum). GN= PE=4 SV=1
-LKVLILEDVPLDAELVIRELQRDGIEFEHLTSEDSFRRALEEFSPDIILADHALPSFDGVSALRIVRENYDIPFIFVSGKIGEEFAVDMLKAGATDYVL
KNNLSRRALQEAEEERKIKKARKE---SERKYRALFEKSGNPIFIC------STDGIILDVNPAAAGFLKSFRE---DIIGR-NIREWIHEE--------
---DADRIF--------------RDGEGGHLKFRVGLRGRT--LDTSVTA--------------------------------------------VELDHE
KLIYIMGKDV----TAQKRIEKELKSSKEEYRVIFENTGTLTVICGSDMVIELANSAFEEFSGYSKGEIQGMKFTDFVDASDAARIYRLKGINPDAINFE
VVRQGEERNFFATSVVI--PGS-ERCLISL-MDITHRKSVEKEKELLLREVHHRVKNNLQIISTLL-MLQASTTGDKLRDLY-----RDSQRAISLIHEK
L----YESR----DLSRVNLRDYIKTLLSDLLDSYG---ADSNGIDVRVKV--DDVRLNIETAIPCGLIINLVSNSLKYADGKGEITVEVHSTGEGYEMT
VSDNGVGLPEDL-----------DLE-----GSGTLGLRIVRNLVEQIDGELEIE--RPAR--FTIKFTE---------------
>tr|D9PW39|D9PW39_METTM Predicted sensory transduction histidine kinase OX=79929 OS=100331 / OCM 82 / Marburg) (Methanobacterium thermoautotrophicum). GN= PE=4 SV=1
-VKVLILEDVPLDAELVIRELERDGIDFQHLTSEDSFRRALEEFQPDIILADHALPDFDGVSALRIVRERDNIPFIFVSGKIGEEFAVEMLKAGATDYVL
KNNLSRRALQEAEEERKVREAQRE---SERKYRALFEKSGNPILIC------SPEGTILDVNPAAAGFLKSFAD---DITGR-NISEWISEE--------
---DFKRLM--------------GDCEGGPMKFTVGLRGRT--LDVSVTA--------------------------------------------VEVDDE
KLIYLMGKDI----TVQKRIEKELKASKEEYRVIFENTGTLTIICGSDMVIELANSAFERFSGYSKGEIQGMKLTDFVDPSDAGRIHRLMSVNPDAINFE
LTRRGEERNFFATTVTI--PGS-KKCLLSL-MDITHKKSVEKEKELLLREIHHRVKNNLQIISTLL-MLQASITGDPLRELY-----MDSQRAISLIHEK
L----YESR----DLSRVNLRDYIKTLLSDLLDSYG---ADRSEIDVRIRV--DDVMLNIETAIPCGLIINLVTNSIKYADDGGEITVEVHRNGGRYTLI
VSDNGVGLPEDL-----------DLE-----NISTLGLRIVRNLVDQINGELKIE--RPAR--FTVKFRE---------------
>tr|C5JBQ3|C5JBQ3_9BACT Sensor protein OX=77133 OS=uncultured bacterium. GN=bu93_0100 PE=4 SV=1
--IILIADDDEEMLALYHRHLDDGQVRMLVVTDGLEALAVFEREQAHLVILDAIMPKMDGFAACAALRRRDALPILIVTAMEDNHSVAKAFAAGANDYVT
KPVHWEVLRQRMHHMLRHVHALRAASREELRASR------NNFKSIFD---QAHDGILVE----QGSLRCTMANRTQQEVTRLHLLDMELGHAIFTSYRQ
QDATAIT--------THHDLALQGEAGVVVYVDSVSTVVLEGQ-------R---------YL-MGIFRDATQ-RRQAQARQRA-----HAERLHLLMKLD
RRARELT--VQELCDQAVEIAVELTASQAGMLAILSDDHSACTHLSRSRHLQKLDTQVAVTTGIWADCIRRLPVNDGGSWSEGYGLPT----GPVPVARC
MSVDGTRKILTVKVEPY-DD-HDVQQLQLIFQDVEKRRRSNRAKTDFLAAMSHEIRTPMNGVLGMADLVLRTPLTD-QQRHYVETIHRSGRTLLRIINDI
LDISKIHAGHLALELLQFDLAEVVQDVIDMFAERVK-----TKGLTFAIEFPEEGMPVLGDPYRLSQILFNLLGNAIKFT-ERGSIGLFVEVLEVLLRFK
VTDTGIGISPDYCQRLFQAFTQEDLSITRKFGGTGLGLAITQKLVGMMAGELTVESTQGQGSIFQFTAHFG--------------
>tr|A0L6G0|A0L6G0_MAGSM PAS/PAC sensor hybrid histidine kinase OX=156889 OS=Magnetococcus sp. (strain MC-1). GN= PE=4 SV=1
--RVLIMDDNEPLGRFYQMLLELAEMEVVYIREAEELLPAIQRFKPEVLLLDLYMPDANGLEIAAVVRQSADLPILLMVENNAG-RRILDQTKESESFLI
KPVQPRAVIERVRQRVGRVEYMRSALHELEIVSVTD--QDGNI-----TFVNQKFCQTSGYTPNELIGNQHPASF-----YQEMWATITQGQTWHGQVKN
-----RR-----------------KNGTTYWVSA-------------------------TIVP----------------------FLDGDGTPREYISVR
TDV-----------TAQKAAQERYRASEQRLRAILDNTHEGVVVMEASGQIEMLNPAAARIFGYTLADMPQPTIQWLLPE---FPLTDILNDAHLHHANL
NRSDGSRMLLGVSVSSFHLEES--AVCVAVVRDITARKMEEQAKTRFLSSMSHELRTPMNAILGFAQVMQSDP-NEPLSEETREIIQA-GGHLLELINDV
LDLAKIEENRISLKMAPVHVQEVIREAVALVTPMAN-----RKGIRLYHGMGEERCDVQADRTRLKQILINLATNGVKYNREGGEVEISCRLEAGRARIE
VRDTGIGIAALKQGDIFEPFHRLVED--GTIEGTGIGLSIVKRLVEAMGGTLGLESQEGQGSRFWFQLPNS--------------
>tr|Q5V4G4|Q5V4G4_HALMA HTR-like protein OX=272569 OS=B-1809) (Halobacterium marismortui). GN= PE=4 SV=1
--HVLQVDDRP-LLDETVEFPGPDSLTLTTTDRADSALDRLEGTAIDGIVAADNLPDRSGREFAEIVREDSNVPVLLLT--EPESVASDAISNGVTDVFR
RDTARRDLLAN---------RIRLLVEHHR-STELA-----------------------SRTQQLTELA-------------EQSSELLWVFS--GDWEI
QFVN-----S----------AYETL--YGRSVES-----LQTSPDEFMTA-----------------IHPT---DQDRVIQSMQRVSAGESRAKAQPIED
GTVARIVGASRDITERKRCE-SEHIAEIDRPDAPVDAVPDLFYELDENGELARWNDALAAATGYTDADLGPMSLTALFAPSDRETVRQGIETAFSTGETS
FTADGTTVPYETGGRITAADGS-PLGVVGIGRDISAREALEQQNGEFASVVSHDLRNPLDVARGQLELAQIEHD-----SDHLDAVKRAHGRIGQLIDDL
LTLAQNGE--TALDSEPVPLQTVVEQCWQTVET---------GDTTLELQ---TSTVVRADPSRLRQLFGNLIRNSVEHGQPAADLTLTVGELDDGFY--
VADDGVGIPAGERDTVFEGGYSL------AS-GPGFGLRIVDEIVDTHGWSITVTESDAGGARFEIT------------------
>tr|G0HXB7|G0HXB7_HALHT HTR-like protein OX=634497 OS=102182 / NCIMB 2187 / VKM B-1755). GN= PE=4 SV=1
--RVLHVDDDRQYAETTAAFLERVAFDIEIATSARKGLRLLETAAVDCIVSDYEMPGQNGIDFLESVREYPDLPFILYTGRGSEAVASDAISAGVTDYLQ
KAPSHYALLSN---------RIVNAVKQYR-SQRAL-----------------------EASDRLSLFI-------------DQSPLGFVEYN--QDFEI
VRVN-----E----------TLTEI--FGYTETE-----LLGETEIFVSS-----------------ESYD---DVDAVTSALSE-ASGGYNRLVTD-DS
GDVVTIFSHCQDVTERIEHE--QNLAQLRDFFAEAEELGALAWEYDESG-MSTWTAGTRRIHEVDDDDPTVEDGLSFYHPEDRETVSDAVDAALNDGDPD
LTARGNHRWVRRGKRVEGAEKP-TVRGFI--QDITEQKRLRVQNDSFASVVSHDLQGPLTVAQGHLELAQQDVA-----NDHLDSIDAAHERMQTLIDDI
LTLAREGR--EATTTEPVTLQTAATACWETIET---------ESAALETD---TDSVVLADPGRLQRLLSNLFRNCVAHGSNGGGVTVTLGDIDSGFY--
VADDGPGIPEDERNTVFEAGYST------ASEGTGFGLAIVADIAAVHGWDVSVTDSESGGARFEIT------------------
>tr|G0HPX1|G0HPX1_HALHT HTR-like protein OX=634497 OS=102182 / NCIMB 2187 / VKM B-1755). GN= PE=4 SV=1
--HVLQVDDTP-LLDETVEFPDPDSLTLTTTDRADSALERLEDNAIDGIVTADDLPDRSGREFAEIVREDSNVPVLLLT--ESESVASDAVSNGVTDVFS
RDTGRGDLLAN---------RIRLLVEHHQ-STETA-----------------------SRTRQLTELA-------------EQSNELLWVFS--GDWEI
QFVN-----S----------AYETL--YGRSVES-----LQADPAEFMTA-----------------IHHT---DQERVMQAMQRVSAGESRAEAQPIDD
GTVTRIVGASRDITERKRRE-SERITELDSPDAPVDAVPDLFYELDENGDLVRWNDALAAATEHEDADLESMGLTAFFAPSDRETVRQGIEAAFETGEAS
FTAEGTTVPYETGGRITAADGS-TLGVAGIGREISTLDALEQQNDEFVSVVSHDLRNPLDVARGQLELAQMEHD-----SEHLDAVERAHDRIGQLIEDL
LSLARNGE--AALDSESVPLQTVVEQCWQTVET---------GDATLELR---TAAVVRAAPSRLRQLFENLIRNSVEHGQAATDLTITVGELNDGFY--
VADDGVGIPADEREDVFEGGYSL------AS-GPGFGLRIVDEIVDTHGWSITVAESDAGGARFEIT------------------
>tr|Q3ITY1|Q3ITY1_NATPD Receiver/sensor box histidine kinase OX=348780 OS=Natronomonas pharaonis (strain DSM 2160 / ATCC 35678). GN= PE=4 SV=1
--RVLHVDDEPGFAPLTAEFLEHAAIEAETTTDPAVALDRLAESTFDCVIADYAMGGWDGIELLRAVRNYPDLPFVLFTGEGSEDIASRAVAAGVTEYIP
KREDRYELLAN---------RVLKAAREYQ-PDDEH-----------------------EPQRRRDDLL-------------QKTQEIAGI----GAWDV
LYWT-----D----------QTAVL--HGVSPE------YDPTLSDAIEL-----------------YHPD---DRAKLRDVMRSIDEGRPRARGEPQGE
SGVVRIHGTVRDITSQKRRE-VRLAGENNRLQSVIENVPVALFLKDADGRYLLMNQYFRETFDVDAESVVGLTDYDIFPAEVATELRGDDRQVLETDEPQ
LTEDGPRV-FLHKVPIAGDDGT-PQAVCAVAADITDHKRLERKNEEFASVVSHDLRNPLRVAAGRLELLAEDCD-----SDHIDDIENAHDRMERLIDDL
LSLARQGE--PATETEQLSLQTVAKAARETVET---------NGATIEIE---SDTDIVADESRLRQLVENLFHNAVEHG--GDGVAVTVGDLDDGFY--
IEDDGPGIDREDREQVFETGYST------SDEGTGFGLTIVREIIDAHGWELRLTESDDGGARFEIR------------------
>tr|L0K2D2|L0K2D2_9EURY PAS domain S-box OX=694430 OS=Natronococcus occultus SP4. GN=Natoc_2955 PE=4 SV=1
--DVLHVDDAPNVAETTATVLEDERLAVETATSAEAGLERLSTGTIDCVVSGYEMPGRNGIEFLNAVRDYPELPFILFTGKGSEEIASEAISAGVTDYLQ
NDRSQYAILAN---------RITNAVAEYD-ARRLE-----------------------RLTHDQMAIL-------------DRIDDGVFALD--DDWRV
VYVN-----E----------RATTL--FGAPADE-----LRGSPEVFSEA------------------------------------ADTPFREHIYP-SE
NGLTILFHDITDQKQRKRRYRAENTYQFTGLLDPDGTLVEAETALEFGG-LERESIVGKKLWEVA----------WFQHSKDRERVQEAVERAAN-GEF-
VIQGADREAIIFSVRPLTDERG-TVTLLIEGRDITELVALQRERDEFASVVSHDLRNPLNVATGRLELARAEDD-----NEHLDEIETALDRIDRITEDV
LWLAREGR--DIGSRDAVRLGDAVDAAWKLVAD---------GNARAELRYGIASATVEADDDRFQQLLENLFRNAIEHG--GEDVTVTVGSTDRGFY--
VEDDGPGVPEHHRENVFDGGYST------SEGGTGFGLRIVDRVADAHGWEVRLADG-TNGARFEIM------------------
>tr|A5G9Q2|A5G9Q2_GEOUR Multi-sensor signal transduction histidine kinase OX=351605 OS=Geobacter uraniireducens (strain Rf4) (Geobacter uraniumreducens). GN= PE=4 SV=1
--SILYVEDDPITRDLICTMIKFPGLNLLAAENGQIGLALYKEHRPDIVLTDISMPVMDGIRLASEIRVLPDASIIVITAHSDTRYLLNAIDIGINRYVL
KPIDQEKLFEAIED----------CVA----------------RITLERHVRKQSEYICKLTRAV-EQ----SPCM------------VIITDAKGVVEY
VNPKFTLPEEVIGKTPRIPK--LNARESDTYEKLWSTITA-----GYEWQGEFQSRK----KSGELYWESASISPLF----DAEGV-ITNYVAVK-----
EDISERKRA-----------DNALKESEERYRHLYEDTPVMLHSIDGVGRIVNVSNYWLFHLGYERNEVIGRKSTEFLTEES-SRYAEIVIPAFRSGHCQ
MKKNGEIVDVLLTAVAEWNATGEVIRSQAVMVDVTEQKRAEQIREAFCYAISHELRAPIARLEGFREVIFECFKSGDGDLQYVGRLGCSVQQLKSAVDAL
LMMNRLSK-T-EITSEPINLSELSRQVMAELIEVH-----GERTMQFRVA---PDVFARGDRKLLNICMHNLLGNAYKYTLPLASIEFGAESRADQKVYF
VRDNGAGFDMAYVSKLFQPFSRL-HS-EKEFKGTGIGLATVHRIIEKHEGKIWAESKVDEGATIFFTLGQ---------------
>tr|D0LYI0|D0LYI0_HALO1 Multi-sensor signal transduction histidine kinase OX=502025 OS=Haliangium ochraceum (strain DSM 14365 / JCM 11303 / SMP-2). GN= PE=4 SV=1
-NRILLIEDNQDDHILVDAFLPEGAYTITWCQTAREARRQLGTQRFDLVLLDHGLPDSNGLSFLEELRVAPESPVIVLTGRNDQALAVSALKMGAHTYLL
KDE--------IPEHL------AEAVAEALPCR-----TPSPVDKRPDSFVD--------TAERFYQI------FM------ESVDEGCLVVDQSGDITF
FETMVRR----DVQSPGRSVYDLTPESAGRLR------ASLWRLSTAQSSTSV--VMEAT---LNASYARR-SGELTTVRIAMRHDRDGSYQAGLLILT-
-DISEVLHAKQLLAERYM----YEKAQHNQLRAILESSRDGIILIDRSLRLRVVNGPMARLLGLAEGYWIGKSLVELTLTHRSPELTQAVLSEGDESSNT
ATVGQRALRW-LDLPVQGDDSR-----LVAMQDVTAEQTVQQMRDDLVHMAVHDLRNPLGVIRQSFEILTDDAWND--ALAWLDLGREGTSQMLRLVTAI
LDAHRLDTGQMPLQRSACSLAELVQRVVHAQTPIAN-----AREVRIARELTP-GAHGWIDVSLIERVLQNLLDNAIRSSPPGGTVRVSAQPDEAYHCLV
VADEGGGISPALQERLFQRFATGRR------QGVGLGLAFCKLAVEAHGGRIWVESKPEQGATFRFLVPA---------------
>tr|H1Z070|H1Z070_9EURY Multi-sensor signal transduction histidine kinase OX=937775 OS=Methanoplanus limicola DSM 2279. GN=Metlim_2077 PE=4 SV=1
--SLLYVDDEAVLIDIMKAFIQQYEFTLDSANCAAEGLIKLNTNHYDAVISDYQMPETDGIEFLTEIRNTGEIPFILYTGKGREEVAIKALNAGADYYLQ
KGVNPKELVNFVR-HAVAKNKAEKAVREQK----SKMADV--MNFLPDATFAIDNSGKVIAWNRSMEKIYVLNKHLVEKLIAETFAPEIRCYNSSGEITG
RDISDESAEKELIKKDAVFEVFETVLGNRYYQYELSPKDVGGIRQNIQLKEIIDNIEDIFYITAHKILGYSPEKR-EEL-KSLLEK-NGDYDVCFRNKYG
QICGVEGIIRDISSRKSAEIIEKLRNKDCLINTVFSASPVYYYVYDRDLNFVYASPGGAEVLGVTPEEIIGKKKSENSRNVDF-AYDDNLRKVFATGRGE
SSAEGI-RHFIYELSPVTGKDGLNEFVVSTAIDITGYKEKEDTLKKIVPDSSSCEIEDDRFWKENKTEIRNGSWINGALRMVMDITHDTFNKITGILLDL
LNLEYIEGLVD-AISEELEFARDYEDIWQDFAGYLSNE-KIPRGIFVSADFS--GIEILADP-MLGKVVHNLIDNAVRHGNGVTEITVTHRFTPEGFMII
WEDNGTGILEGLKERIFERGYGT---------NTGLGLFLVREILSISGITIRENGARGSGARFEILVPD---------------
>tr|Q2FP57|Q2FP57_METHJ PAS/PAC sensor hybrid histidine kinase OX=323259 OS=Methanospirillum hungatei (strain JF-1 / DSM 864). GN= PE=4 SV=1
--SVLYVDDEPDLLDLGKIFLERTDFRVTIATGVKEALSAMEGSEFETIISDYQMPGMDGIGFLKHLRSHGKTPFILFTGRGREEVAIEALNNGADFYLQ
KGGDPRELANKVR-YAASHRRAEKQILDLQ----QRESEI--INFLPDATFAIDTSHVVIAWNRAMERLYVLDNDPEHTLTAEITRPWFWIYDMKGNVIG
RDITPLKARELLEDTASNEEHISTKQGGWKWIWDEDGPVRVGKLETLNLTQMTEKSMSDIYLTYVAFLSDDVMEE-CQI-RDQKKLYWGRQRRPVITNNR
IVMRQLTLLMNIIQRKQSESQEDIRESEERFRAVFNSTLVGIAITTPDGRWLYFNDALCSMLGYTAEELNQIRWTDITPAEDL-VEEMKIFESVLAGKLE
IRKDGS-IIDLISTGIVRKQDGSIDYLCSIILDMSEKKASERLQRLIIENVPPSLSSP-LNIRDIGNPVQSGKVREDDLVSIRDITHDILNQVTALLGEL
LYIKKCLSCTT-TIRSQIAFTKLVDDIWQYAERMITHV--LEGYSIITCQVDLKGLYLYADP-ILEKVIFTLIENSIRHGENVTRIAFSYRIDDGDCIFV
YEDDGSGIPDDEKEKIFRQGYGK---------HTGLGLFLIREILAINAMTISETGAWGSGARFEIRVPA---------------
>tr|G6FLB5|G6FLB5_9EURY Multi-sensor signal transduction histidine kinase OX=882090 OS=Methanolinea tarda NOBI-1. GN= PE=4 SV=1
--SVLYIDDDKDLLLLGKAFLERMDFSVETAGSAKEGLALLAEKKFDAVISDYQMPSMTGLDLLKAIRAKGGIPFIIFTGRGREEVVIEALNAGADFYLQ
KGGEPKELAHKVR-QAVTRRRAEMMVDESR----KRLADI--IDFLPDATFAIDREGKVIAWNRAMEEMYVLSPREDTTLTAETILERYWGYDENGEPAG
RDITDRRAEEILTQVPASIEIMRTKGGG----LHVTVPARFGRRKREQFRRIVETAHEGIWTTLASLLGYTFMPE-SEL-ADSREKFAGEYERRVLHRNG
TFRGSFAMLTDITEKKQLARMETLAKSEEKFRRIVETANEGIWEMDENFRTTYVNPRMASLLGYTPEEMLGREITSFMPESER-EDNLEKIRDRMAGKYE
LHRDGS-VRIHVSATPVFDDNGTFRGSFTMLTDITEKKRIERMYRRIISGTSRQDIVG-RNVLNFQSPLLDGSPVKPTIVAFRDITHDIQNKVTVLSGTL
LCLESLENTLH-AIQQIIDFTRTYQDLWQAVSDVAGRV-MLEGIAVLDCSCE-----VFADP-MLEKVFYNLIDNALRYGGDISGIRISCTKEDGDLVIA
FEDDGVGIPDDQKEHIFEQGYGK---------GTGLGLFLSREILSITGIGIRECGTPGSGARFEIRVPQ---------------
>tr|Q2FLH6|Q2FLH6_METHJ Multi-sensor signal transduction histidine kinase OX=323259 OS=Methanospirillum hungatei (strain JF-1 / DSM 864). GN= PE=4 SV=1
--KILLVDDEDVVLHATREYLKTCSFDVDIAVSGSSALARLSENEYDAIIADYEMESMSGLDLLKAIRERGDTPFIIFTGKGREEVVIEAFERGADGYVQ
KGGEIRELAQKVR-TAVCSTRSARAVHEQD----TRHRIL--FETMGQGVIYQDRDGTIIEANPAAERID-----P-GKVIADTIMGIRW-FNGDE----
SDITGLAI-----------------------------------RETEALNYAIESSMNGIALTFLSIWNYHHDQA-AE--------------------SG
TPQAIMASFIDITDKKMAE----L-------EGMLNGI------QLPNHSVVRYNKAGYEALGLSASEVVGKKCYEL-PCVPC-ATSEAI----------
SPEIG-----ECTSNPILNDQGKPELIVELLHDITSQKKAEEAFRQLFNNASHEELLE-KAVFDIGHALKDGSIFSRVLSICRDITHDILNSLGGLLLDS
INLHRIEAYAL-TIQKQIKFTHDYQVLWQDLSRCFQKA-SDTGRITVEEHLS--GIEIFADP-MLEKVIYNLIDNALRYGGKLS-IFGYYRTDGEDLIWI
IEDDGAGVAPEMKDQIMERGVGC---------NTGFGLFLSAEILSITGMTITETGTDGEGARFEIRVPK---------------
>tr|G6FKA7|G6FKA7_9EURY Multi-sensor signal transduction histidine kinase OX=882090 OS=Methanolinea tarda NOBI-1. GN= PE=4 SV=1
--RILYVDDEPALLDIVRLYLERKRFIVDTATSAGEALKMMQGNPYDAIVCDYQMPVMDGVGFLRVLRKHGDTPFIIFTGKGREDIVIQALNEGADFYLQ
KGGDPAELAHVIQ-KVVRQKRIESSIRDME----RREADI--LNFLPDATVAIDLRGTVIAWNRAMEKMHILQSDPGETLISEIFIPSLWFYNSRGEVVG
RDVSEWDMEKEMEERANLPEILATRHGETRWVYSEDGLLYEGRRRSEQLALAIEGSGAGLWELWAEIVGYTLVHP-DDL-EVSNSLLAHSYECEVRMREG
RPVRMTGTHLDITERKRIE--EELRESREILHNFIGNLPVGLYRNTPGARGEYINPYIARLHGFTLDELFTHPAADLYPSERL-AFSDELVRASVFGR-E
RRKNGE-RFWRVSAVAVRDEKGNVKYFDGVIEDITEQKKAEKAYRDLLEKLKPEEVIN-RHVLEFQETEKDGTRREPTLIVLFDITHDISNHLLVLTGEL
LLLDKVRRAAA-RISAAIQFTKDYEKIWQDIHDLVETA-KVSPELVIENQIPR-GLLVFSDS-MLAKVITNLIDNSVRHGGNVTSIRFSTAGEGKNLLIA
YEDDGAGIPDGEKEMIFERGYGK---------NTGWGLFLSREILAITGMSIRENGVPGEGARFLLTVPG---------------
>tr|Q1NWX0|Q1NWX0_9DELT Response regulator receiver OX=262489 OS=delta proteobacterium MLMS-1. GN=MldDRAFT_0938 PE=4 SV=1
---VVVVDDDAAIRGPLRQYFAAEGLAVEECGSGAELLALLEHRRVALVLLDIGLPDYDGVALLPRLEKNPDGAVVMLTGVADLQVALDCMRQGATDYIS
KPASLEQIFHVASKALE-----------------KRRLILEN----------RQYQEELEEAHFRLRLLHQLSLKMNSVYSTVELDEILR---------A
VLV-----------------GITANEGLGFN-----------------RAFLLM-------------FDE-QQ---RELR-GHMAIGPGCRE-----EAS
QIWGEMQERGVDFSQILDGIRGQRWRKDVEINNTVRRLSVSAAAEDNL-LIRAVASRRSALVGRE---APGVPILLAPNSAPNGNGVQLPEGETLPRPSG
LETLDEEH-F--VVVPLYSPSR-SFGVLLADNYVTNLEAVEAERYQMAAQLVHTIRNPITSIGGVSR-ILAKKTSDESWLKYINVITKETARLESTLADL
FD--FVNQE--KIEKRPLLLCGLLRKTMLLLQNELQ-----RHGIEWEIHCPEGGVSANVDERLMRQVFLHLLKNGMEAMPDGGRLTVEAAEEEQWAVVR
VRDTGGGLVNSQLERARDPFFTT-KT-----YGTGMGLTLVEKAAEAHGGTFSLKTAHNGGMEAVVRLPRS--------------
>tr|D6Z516|D6Z516_DESAT Multi-sensor signal transduction histidine kinase OX=589865 OS=Desulfurivibrio alkaliphilus (strain DSM 19089 / UNIQEM U267 / AHT2). GN= PE=4 SV=1
---AVIVDDDPAIREPLHRYFASHGLAVEECADASSLLDLLTRRKVALMLLDIGLPDIDGVTLLPRVEKDSDIAVVMLTGVADLQVALECMRQGATDYIS
KPANFDQIFHVARRALE-----------------KRRLLLEN----------RKYQEELEEAHFRLRLLHQLSLKMNNVYSTVELDEILQ---------A
VLV-----------------GITAQEGLGFN-----------------RAFLAM-------------FTK-DD---KELR-GHMAIGPGCRE-----EAG
RIWGEMREKGMDFGQIVQDIKQRCTQDDSEVNRIVRRLTVSADEHDNL-LIKAVNSRRSALVSRE---LGGFPLLLHRNGEKDGNGGHLPAGDPLPVPHE
LSILGEDS-F--VVVPLYSPGR-AFGVIIADNYVTGLEAVEAERYQMAAQLVHTIRNPITSIGGVSR-ILEKKSDDESWGKYIKVITRETARLESTLNEL
FD--FVSQV--KLEKQPLQLCDLVKKTLLLLQQELK-----RQQITWDILCPPGGVTANADERQMRQVFLHLLKNSVEAMPHGGQLTITILVEEEQAVVK
VRDTGTGLPSSQVERARDPFFTT-KT-----YGTGMGLTLVEKAVEAHGGTFSLKTAKNGGMEATVRIPL---------------
>tr|E8RK49|E8RK49_DESPD Multi-sensor signal transduction histidine kinase OX=577650 OS=Desulfobulbus propionicus (strain ATCC 33891 / DSM 2032 / 1pr3). GN= PE=4 SV=1
---IVIVDDFADIVGLLEDFLHQQGFATVAAGSADALRRQLGMHKVALALLDIGLPDADGIKLLPELQHDRDLAVIMLTAVTDLQTALACLRLGADDYLA
KPVHFTDLLATLRRVLE-----------------KRRLTIRN----------RQYQQQIEQANFRLQFAHQLAMKMNTAYSMVELDEILH---------A
ILA-----------------GITAEEGLQFN-----------------RAFLAL-------------FNE-AG---DVLE-GRLAIGPGNRE-----DGS
RIWRDLREQELGLRDLFVRIQRNETAMDTEVNRIVRALRVDALDADNL-LIRAVRNRQSINV------------------------------SEYPVPLE
LGLLQEDS-F--VVVPLYSPSR-ALGVIIADHFVNELEEVEAERYHMAAQLAHSIRNPITAIGGTAR-LLSRKIDNKEWLRFLGMMAGEAEKIEKTLEDL
FS--FVDQV--KPEREKIRLIPLIHKSLLLHLAAIK-----AQGIKKILLLPETDPLIDADPRLIQQALVHLIRNSVEAMPQGGELFIEVVLEEAQVKIL
IRDSGTG--G--LRHATDPFYTT-KL-----VGTGMGLTLVKRIVEDHGGRLTLDNRQQGGVRATVLLPRV--------------
>tr|E6W1K6|E6W1K6_DESIS PAS sensor protein OX=653733 OS=Desulfurispirillum indicum (strain ATCC BAA-1389 / S5). GN= PE=4 SV=1
--HILLVDDSRTIIAIIEEMVSELGEPTVFHLDPLEALQWCQNHDVDLLLVDYMMPAMNGLEFLRHFRQKEQIPALMITANLDPQVRYEALQDGVNDFLN
KPLDEIEFKARIRNMLRRHQIFRLRVAQRVAQLGSWEMDAS----SGDIWLSAEHGH----------LLGHCDQSSGCSMPLN---------DYID--RY
VDP----LDQ--------------------SMVRETCRNALSQLSCQSLSSLSFEFRVNTANDRRTFWL--YATPMEQQ--------EGE----------
----NLTRLFGIVQDISQ--RKERESQLRKLSLAVEQSASTVMITDTDGNIEYVNPRFTEATGYTFAEVQGKNP-RLLKPEGVCALWENITAGRQWLGEL
RNRGSCYWQLASIFPLLDDNG-TITHYVGIGEDITAQKSLEESNREMIGAIAHHWRQPLNTVGLMVQKMQISELSSETMARFVRETMMTLQTMSRVIDEF
RDIF--EP---DCSLEQFSLESTLSSALKVVRAQMD-----NNHIQVGVDKPSQDIWIRGYPKEFQQVLLSVLGNAIVLSGTRGRIHIQVNLQNQQVVLS
IHDNGGGINPAIMDRIFEPYFTT-KERGRGSTGTGIGLFMSKMIIEKMQGKLSASNID-GGACFEIVLPLP--------------