| VP4 -force run |
| ID: | 1513623973 |
Query Sequence |
Download Alignment We filter this alignment to remove positions that have > 50% gaps before running GREMLIN. |
| Length: | 774 (771) | ||
| Sequences: | 66 (24.4) | ||
| Seq/Len: | 0.086 | ||
| Nf(neff/√len): | 0.9 |
HHblits Results: (2016_02)
Sequences per length for each position, BEFORE the coverage/gap filter was applied
Legend: Dots above the red line, indicates positions where there is > 5 sequences per length (if visible, green bar = 20 seq/len). Point of this graphic is to give you an idea if resubmitting a sub-portion of your sequence might help increase the overall Seq/Len (which after applying the coverage filter is at: 0.086).
Sequences per length for each position, AFTER the coverage/gap filter was applied
Residue pairs sorted by coevolution strength:
Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] covarying residues with sequence seperation > 3. The i and j are positions as given in the input sequence.
| i | j | Scaled score | Prob |
| 226_P | 589_S | 2.363 | 0.54 |
| 586_S | 589_S | 2.156 | 0.44 |
| 226_P | 591_W | 2.032 | 0.39 |
| 586_S | 591_W | 1.998 | 0.37 |
| 629_L | 725_I | 1.983 | 0.36 |
| 177_Y | 217_T | 1.956 | 0.35 |
| 586_S | 590_A | 1.892 | 0.32 |
| 226_P | 231_R | 1.864 | 0.31 |
| 209_P | 649_I | 1.843 | 0.30 |
| 226_P | 229_N | 1.786 | 0.28 |
| 589_S | 592_T | 1.775 | 0.28 |
| 226_P | 230_T | 1.765 | 0.27 |
| 35_I | 514_M | 1.721 | 0.26 |
| 226_P | 586_S | 1.708 | 0.25 |
| 586_S | 592_T | 1.643 | 0.23 |
| 60_T | 610_T | 1.635 | 0.23 |
| 226_P | 232_N | 1.625 | 0.22 |
| 238_I | 341_K | 1.619 | 0.22 |
| 199_V | 547_N | 1.600 | 0.21 |
| 682_A | 725_I | 1.575 | 0.21 |
| 238_I | 538_V | 1.568 | 0.20 |
| 226_P | 590_A | 1.552 | 0.20 |
| 332_S | 689_F | 1.551 | 0.20 |
| 142_D | 580_T | 1.538 | 0.20 |
| 92_V | 226_P | 1.537 | 0.20 |
| 35_I | 606_I | 1.532 | 0.19 |
| 673_V | 679_V | 1.528 | 0.19 |
| 514_M | 539_D | 1.525 | 0.19 |
| 238_I | 762_K | 1.482 | 0.18 |
| 345_I | 725_I | 1.471 | 0.18 |
| 26_G | 464_I | 1.445 | 0.17 |
| 536_S | 641_T | 1.441 | 0.17 |
| 440_S | 561_V | 1.437 | 0.17 |
| 476_S | 668_N | 1.433 | 0.17 |
| 118_N | 584_V | 1.430 | 0.16 |
| 341_K | 762_K | 1.429 | 0.16 |
| 353_I | 629_L | 1.423 | 0.16 |
| 495_D | 654_I | 1.420 | 0.16 |
| 52_P | 668_N | 1.417 | 0.16 |
| 180_T | 495_D | 1.416 | 0.16 |
| 197_V | 553_K | 1.413 | 0.16 |
| 581_M | 584_V | 1.410 | 0.16 |
| 35_I | 696_F | 1.409 | 0.16 |
| 26_G | 220_I | 1.409 | 0.16 |
| 345_I | 440_S | 1.394 | 0.16 |
| 159_L | 204_D | 1.392 | 0.15 |
| 256_I | 406_S | 1.389 | 0.15 |
| 304_N | 556_K | 1.384 | 0.15 |
| 222_N | 325_D | 1.370 | 0.15 |
| 328_Y | 712_D | 1.370 | 0.15 |
| 160_S | 622_M | 1.370 | 0.15 |
| 229_N | 232_N | 1.368 | 0.15 |
| 55_I | 658_V | 1.361 | 0.15 |
| 629_L | 682_A | 1.358 | 0.15 |
| 514_M | 538_V | 1.357 | 0.15 |
| 92_V | 230_T | 1.357 | 0.15 |
| 312_V | 584_V | 1.353 | 0.15 |
| 767_N | 770_M | 1.349 | 0.14 |
| 278_N | 429_N | 1.347 | 0.14 |
| 339_I | 652_N | 1.346 | 0.14 |
| 545_A | 658_V | 1.342 | 0.14 |
| 231_R | 589_S | 1.340 | 0.14 |
| 115_E | 585_G | 1.333 | 0.14 |
| 306_D | 429_N | 1.329 | 0.14 |
| 580_T | 650_T | 1.326 | 0.14 |
| 128_L | 767_N | 1.326 | 0.14 |
| 404_L | 424_L | 1.325 | 0.14 |
| 194_Y | 590_A | 1.323 | 0.14 |
| 616_R | 704_Q | 1.322 | 0.14 |
| 9_L | 765_I | 1.315 | 0.14 |
| 151_S | 204_D | 1.315 | 0.14 |
| 342_Y | 689_F | 1.315 | 0.14 |
| 56_N | 171_G | 1.312 | 0.14 |
| 479_D | 735_T | 1.309 | 0.14 |
| 587_T | 696_F | 1.307 | 0.13 |
| 76_P | 592_T | 1.307 | 0.13 |
| 100_N | 588_A | 1.307 | 0.13 |
| 461_F | 580_T | 1.307 | 0.13 |
| 147_S | 151_S | 1.305 | 0.13 |
| 186_T | 580_T | 1.304 | 0.13 |
| 298_P | 752_E | 1.301 | 0.13 |
| 194_Y | 586_S | 1.297 | 0.13 |
| 194_Y | 589_S | 1.294 | 0.13 |
| 189_Y | 284_S | 1.292 | 0.13 |
| 363_R | 498_L | 1.291 | 0.13 |
| 128_L | 579_Q | 1.290 | 0.13 |
| 116_T | 647_V | 1.287 | 0.13 |
| 25_V | 209_P | 1.285 | 0.13 |
| 587_T | 590_A | 1.284 | 0.13 |
| 226_P | 233_V | 1.284 | 0.13 |
| 256_I | 757_E | 1.280 | 0.13 |
| 514_M | 649_I | 1.278 | 0.13 |
| 134_S | 345_I | 1.274 | 0.13 |
| 440_S | 522_T | 1.270 | 0.13 |
| 125_Q | 696_F | 1.267 | 0.13 |
| 214_S | 503_E | 1.267 | 0.13 |
| 541_A | 751_R | 1.267 | 0.13 |
| 511_Q | 580_T | 1.262 | 0.12 |
| 282_V | 294_L | 1.260 | 0.12 |
| 198_K | 306_D | 1.260 | 0.12 |
| 547_N | 680_F | 1.259 | 0.12 |
| 341_K | 647_V | 1.255 | 0.12 |
| 661_A | 684_T | 1.253 | 0.12 |
| 160_S | 605_T | 1.248 | 0.12 |
| 403_I | 514_M | 1.246 | 0.12 |
| 236_L | 495_D | 1.246 | 0.12 |
| 194_Y | 591_W | 1.243 | 0.12 |
| 138_W | 456_N | 1.242 | 0.12 |
| 163_K | 296_F | 1.242 | 0.12 |
| 265_M | 682_A | 1.242 | 0.12 |
| 93_A | 767_N | 1.241 | 0.12 |
| 126_E | 740_F | 1.235 | 0.12 |
| 52_P | 687_R | 1.231 | 0.12 |
| 429_N | 680_F | 1.231 | 0.12 |
| 595_V | 650_T | 1.231 | 0.12 |
| 2_A | 773_R | 1.228 | 0.12 |
| 656_E | 725_I | 1.228 | 0.12 |
| 238_I | 325_D | 1.227 | 0.12 |
| 554_R | 679_V | 1.222 | 0.12 |
| 587_T | 596_T | 1.222 | 0.12 |
| 627_E | 751_R | 1.221 | 0.12 |
| 111_G | 556_K | 1.220 | 0.12 |
| 209_P | 256_I | 1.220 | 0.12 |
| 174_V | 440_S | 1.218 | 0.12 |
| 209_P | 514_M | 1.218 | 0.12 |
| 265_M | 617_L | 1.217 | 0.12 |
| 561_V | 668_N | 1.215 | 0.12 |
| 272_V | 676_N | 1.212 | 0.11 |
| 56_N | 213_E | 1.210 | 0.11 |
| 126_E | 167_V | 1.208 | 0.11 |
| 250_V | 328_Y | 1.208 | 0.11 |
| 229_N | 589_S | 1.205 | 0.11 |
| 255_I | 679_V | 1.201 | 0.11 |
| 651_P | 746_D | 1.201 | 0.11 |
| 267_Y | 270_D | 1.193 | 0.11 |
| 267_Y | 726_K | 1.193 | 0.11 |
| 270_D | 726_K | 1.193 | 0.11 |
| 26_G | 375_L | 1.191 | 0.11 |
| 312_V | 499_G | 1.190 | 0.11 |
| 100_N | 457_G | 1.187 | 0.11 |
| 230_T | 589_S | 1.187 | 0.11 |
| 194_Y | 457_G | 1.187 | 0.11 |
| 590_A | 605_T | 1.187 | 0.11 |
| 503_E | 623_T | 1.184 | 0.11 |
| 20_D | 273_I | 1.183 | 0.11 |
| 568_L | 705_K | 1.183 | 0.11 |
| 243_I | 353_I | 1.182 | 0.11 |
| 14_Y | 81_W | 1.182 | 0.11 |
| 325_D | 540_A | 1.179 | 0.11 |
| 587_T | 746_D | 1.177 | 0.11 |
| 238_I | 403_I | 1.177 | 0.11 |
| 365_M | 702_D | 1.177 | 0.11 |
| 545_A | 716_I | 1.176 | 0.11 |
| 147_S | 595_V | 1.176 | 0.11 |
| 18_I | 551_R | 1.176 | 0.11 |
| 522_T | 767_N | 1.175 | 0.11 |
| 415_F | 679_V | 1.175 | 0.11 |
| 109_E | 138_W | 1.175 | 0.11 |
| 229_N | 586_S | 1.173 | 0.11 |
| 35_I | 403_I | 1.173 | 0.11 |
| 177_Y | 743_L | 1.172 | 0.11 |
| 196_T | 605_T | 1.172 | 0.11 |
| 266_Q | 349_S | 1.170 | 0.11 |
| 25_V | 153_N | 1.170 | 0.11 |
| 541_A | 605_T | 1.169 | 0.11 |
| 236_L | 773_R | 1.168 | 0.11 |
| 155_H | 584_V | 1.168 | 0.11 |
| 162_N | 622_M | 1.166 | 0.11 |
| 62_V | 610_T | 1.163 | 0.11 |
| 35_I | 539_D | 1.162 | 0.11 |
| 5_I | 769_I | 1.162 | 0.11 |
| 587_T | 591_W | 1.159 | 0.10 |
| 124_K | 388_Q | 1.159 | 0.10 |
| 35_I | 418_F | 1.158 | 0.10 |
| 545_A | 751_R | 1.158 | 0.10 |
| 75_D | 195_S | 1.156 | 0.10 |
| 265_M | 725_I | 1.156 | 0.10 |
| 207_I | 756_Q | 1.156 | 0.10 |
| 85_S | 431_S | 1.155 | 0.10 |
| 122_F | 160_S | 1.155 | 0.10 |
| 345_I | 559_E | 1.154 | 0.10 |
| 394_W | 453_A | 1.151 | 0.10 |
| 166_A | 680_F | 1.148 | 0.10 |
| 220_I | 375_L | 1.148 | 0.10 |
| 311_I | 429_N | 1.148 | 0.10 |
| 241_R | 313_T | 1.147 | 0.10 |
| 658_V | 704_Q | 1.147 | 0.10 |
| 500_E | 584_V | 1.145 | 0.10 |
| 610_T | 703_V | 1.145 | 0.10 |
| 313_T | 648_Q | 1.145 | 0.10 |
| 375_L | 464_I | 1.145 | 0.10 |
| 65_I | 711_S | 1.144 | 0.10 |
| 111_G | 304_N | 1.142 | 0.10 |
| 131_S | 238_I | 1.141 | 0.10 |
| 231_R | 591_W | 1.140 | 0.10 |
| 306_D | 676_N | 1.140 | 0.10 |
| 353_I | 595_V | 1.138 | 0.10 |
| 192_S | 670_S | 1.138 | 0.10 |
| 16_V | 627_E | 1.137 | 0.10 |
| 160_S | 176_T | 1.137 | 0.10 |
| 77_P | 226_P | 1.137 | 0.10 |
| 216_C | 498_L | 1.137 | 0.10 |
| 116_T | 238_I | 1.137 | 0.10 |
| 115_E | 606_I | 1.134 | 0.10 |
| 230_T | 586_S | 1.134 | 0.10 |
| 576_S | 703_V | 1.134 | 0.10 |
| 17_N | 575_V | 1.131 | 0.10 |
| 120_N | 440_S | 1.131 | 0.10 |
| 16_V | 762_K | 1.130 | 0.10 |
| 26_G | 374_N | 1.130 | 0.10 |
| 166_A | 272_V | 1.127 | 0.10 |
| 457_G | 725_I | 1.127 | 0.10 |
| 243_I | 339_I | 1.125 | 0.10 |
| 485_M | 567_S | 1.125 | 0.10 |
| 174_V | 282_V | 1.125 | 0.10 |
| 211_A | 350_F | 1.125 | 0.10 |
| 58_S | 138_W | 1.124 | 0.10 |
| 22_I | 548_V | 1.123 | 0.10 |
| 232_N | 586_S | 1.118 | 0.10 |
| 440_S | 675_D | 1.117 | 0.10 |
| 112_V | 117_R | 1.116 | 0.10 |
| 339_I | 566_D | 1.114 | 0.10 |
| 112_V | 607_S | 1.114 | 0.10 |
| 579_Q | 587_T | 1.111 | 0.10 |
| 35_I | 578_T | 1.111 | 0.10 |
| 75_D | 105_V | 1.111 | 0.10 |
| 198_K | 457_G | 1.111 | 0.10 |
| 296_F | 547_N | 1.109 | 0.10 |
| 166_A | 645_K | 1.109 | 0.10 |
| 332_S | 342_Y | 1.109 | 0.10 |
| 11_N | 659_T | 1.107 | 0.10 |
| 266_Q | 351_V | 1.107 | 0.10 |
| 282_V | 446_G | 1.106 | 0.10 |
| 126_E | 214_S | 1.104 | 0.10 |
| 292_A | 304_N | 1.104 | 0.10 |
| 189_Y | 298_P | 1.102 | 0.09 |
| 256_I | 398_S | 1.102 | 0.09 |
| 593_S | 659_T | 1.099 | 0.09 |
| 79_D | 649_I | 1.099 | 0.09 |
| 26_G | 127_Q | 1.099 | 0.09 |
| 147_S | 353_I | 1.099 | 0.09 |
| 564_L | 663_E | 1.097 | 0.09 |
| 330_G | 496_R | 1.097 | 0.09 |
| 80_Y | 97_N | 1.096 | 0.09 |
| 550_K | 746_D | 1.096 | 0.09 |
| 72_T | 282_V | 1.095 | 0.09 |
| 168_M | 708_D | 1.095 | 0.09 |
| 76_P | 229_N | 1.095 | 0.09 |
| 647_V | 762_K | 1.093 | 0.09 |
| 33_V | 273_I | 1.092 | 0.09 |
| 285_G | 532_S | 1.092 | 0.09 |
| 35_I | 145_K | 1.090 | 0.09 |
| 130_V | 440_S | 1.090 | 0.09 |
| 312_V | 674_I | 1.090 | 0.09 |
| 211_A | 273_I | 1.090 | 0.09 |
| 77_P | 232_N | 1.089 | 0.09 |
| 100_N | 341_K | 1.088 | 0.09 |
| 44_G | 166_A | 1.088 | 0.09 |
| 418_F | 608_T | 1.088 | 0.09 |
| 136_T | 585_G | 1.088 | 0.09 |
| 587_T | 605_T | 1.086 | 0.09 |
| 76_P | 586_S | 1.085 | 0.09 |
| 197_V | 339_I | 1.085 | 0.09 |
| 339_I | 375_L | 1.085 | 0.09 |
| 436_P | 580_T | 1.083 | 0.09 |
| 11_N | 762_K | 1.082 | 0.09 |
| 212_Q | 243_I | 1.082 | 0.09 |
| 610_T | 748_R | 1.081 | 0.09 |
| 431_S | 725_I | 1.081 | 0.09 |
| 325_D | 389_L | 1.081 | 0.09 |
| 365_M | 667_P | 1.079 | 0.09 |
| 495_D | 679_V | 1.079 | 0.09 |
| 166_A | 767_N | 1.078 | 0.09 |
| 579_Q | 597_N | 1.075 | 0.09 |
| 128_L | 587_T | 1.075 | 0.09 |
| 310_E | 501_L | 1.074 | 0.09 |
| 2_A | 312_V | 1.072 | 0.09 |
| 656_E | 711_S | 1.072 | 0.09 |
| 300_N | 695_T | 1.071 | 0.09 |
| 265_M | 609_Q | 1.071 | 0.09 |
| 232_N | 589_S | 1.071 | 0.09 |
| 138_W | 653_T | 1.069 | 0.09 |
| 25_V | 111_G | 1.069 | 0.09 |
| 26_G | 243_I | 1.069 | 0.09 |
| 495_D | 542_K | 1.069 | 0.09 |
| 11_N | 120_N | 1.068 | 0.09 |
| 539_D | 649_I | 1.068 | 0.09 |
| 35_I | 101_R | 1.068 | 0.09 |
| 174_V | 670_S | 1.067 | 0.09 |
| 255_I | 547_N | 1.065 | 0.09 |
| 239_T | 538_V | 1.064 | 0.09 |
| 142_D | 746_D | 1.064 | 0.09 |
| 26_G | 212_Q | 1.064 | 0.09 |
| 174_V | 393_D | 1.064 | 0.09 |
| 265_M | 611_S | 1.061 | 0.09 |
| 278_N | 388_Q | 1.061 | 0.09 |
| 49_D | 255_I | 1.061 | 0.09 |
| 285_G | 634_I | 1.060 | 0.09 |
| 522_T | 654_I | 1.060 | 0.09 |
| 16_V | 436_P | 1.060 | 0.09 |
| 255_I | 350_F | 1.060 | 0.09 |
| 456_N | 510_Q | 1.058 | 0.09 |
| 52_P | 476_S | 1.058 | 0.09 |
| 152_Y | 500_E | 1.057 | 0.09 |
| 174_V | 588_A | 1.057 | 0.09 |
| 35_I | 311_I | 1.055 | 0.09 |
| 60_T | 703_V | 1.055 | 0.09 |
| 464_I | 663_E | 1.054 | 0.09 |
| 580_T | 595_V | 1.054 | 0.09 |
| 160_S | 213_E | 1.054 | 0.09 |
| 76_P | 232_N | 1.053 | 0.09 |
| 129_V | 200_N | 1.051 | 0.09 |
| 345_I | 374_N | 1.051 | 0.09 |
| 554_R | 590_A | 1.051 | 0.09 |
| 274_R | 285_G | 1.050 | 0.09 |
| 21_E | 732_Y | 1.050 | 0.09 |
| 350_F | 692_R | 1.048 | 0.09 |
| 241_R | 648_Q | 1.047 | 0.09 |
| 159_L | 189_Y | 1.045 | 0.09 |
| 255_I | 388_Q | 1.045 | 0.09 |
| 92_V | 232_N | 1.045 | 0.09 |
| 563_E | 623_T | 1.044 | 0.09 |
| 406_S | 696_F | 1.044 | 0.09 |
| 613_I | 682_A | 1.043 | 0.09 |
| 1_M | 9_L | 1.043 | 0.09 |
| 1_M | 765_I | 1.043 | 0.09 |
| 3_S | 9_L | 1.043 | 0.09 |
| 3_S | 765_I | 1.043 | 0.09 |
| 142_D | 151_S | 1.041 | 0.09 |
| 511_Q | 656_E | 1.041 | 0.09 |
| 17_N | 495_D | 1.040 | 0.09 |
| 160_S | 705_K | 1.040 | 0.09 |
| 616_R | 630_N | 1.040 | 0.09 |
| 165_Y | 585_G | 1.040 | 0.09 |
| 166_A | 298_P | 1.038 | 0.08 |
| 173_R | 374_N | 1.038 | 0.08 |
| 464_I | 662_S | 1.038 | 0.08 |
| 239_T | 341_K | 1.037 | 0.08 |
| 332_S | 476_S | 1.036 | 0.08 |
| 580_T | 736_K | 1.034 | 0.08 |
| 72_T | 774_L | 1.034 | 0.08 |
| 122_F | 171_G | 1.034 | 0.08 |
| 26_G | 339_I | 1.034 | 0.08 |
| 255_I | 282_V | 1.033 | 0.08 |
| 8_Q | 765_I | 1.031 | 0.08 |
| 83_L | 258_K | 1.031 | 0.08 |
| 11_N | 749_V | 1.031 | 0.08 |
| 522_T | 612_I | 1.031 | 0.08 |
| 30_T | 575_V | 1.030 | 0.08 |
| 696_F | 746_D | 1.030 | 0.08 |
| 236_L | 388_Q | 1.030 | 0.08 |
| 105_V | 587_T | 1.030 | 0.08 |
| 130_V | 619_L | 1.029 | 0.08 |
| 623_T | 703_V | 1.029 | 0.08 |
| 403_I | 649_I | 1.029 | 0.08 |
| 211_A | 674_I | 1.029 | 0.08 |
| 167_V | 594_T | 1.027 | 0.08 |
| 223_G | 474_V | 1.027 | 0.08 |
| 160_S | 545_A | 1.027 | 0.08 |
| 86_P | 674_I | 1.027 | 0.08 |
| 103_L | 204_D | 1.026 | 0.08 |
| 389_L | 680_F | 1.026 | 0.08 |
| 292_A | 711_S | 1.024 | 0.08 |
| 55_I | 584_V | 1.024 | 0.08 |
| 348_N | 394_W | 1.024 | 0.08 |
| 321_N | 552_F | 1.024 | 0.08 |
| 567_S | 652_N | 1.024 | 0.08 |
| 325_D | 611_S | 1.023 | 0.08 |
| 661_A | 741_N | 1.023 | 0.08 |
| 345_I | 407_A | 1.023 | 0.08 |
| 371_L | 631_F | 1.022 | 0.08 |
| 183_N | 296_F | 1.022 | 0.08 |
| 545_A | 654_I | 1.022 | 0.08 |
| 766_E | 773_R | 1.022 | 0.08 |
| 62_V | 596_T | 1.020 | 0.08 |
| 587_T | 592_T | 1.020 | 0.08 |
| 595_V | 656_E | 1.019 | 0.08 |
| 658_V | 746_D | 1.019 | 0.08 |
| 397_M | 664_K | 1.019 | 0.08 |
| 680_F | 683_G | 1.019 | 0.08 |
| 138_W | 656_E | 1.017 | 0.08 |
| 35_I | 87_D | 1.017 | 0.08 |
| 256_I | 773_R | 1.017 | 0.08 |
| 77_P | 229_N | 1.016 | 0.08 |
| 339_I | 488_V | 1.016 | 0.08 |
| 612_I | 658_V | 1.016 | 0.08 |
| 127_Q | 619_L | 1.016 | 0.08 |
| 106_I | 339_I | 1.016 | 0.08 |
| 446_G | 575_V | 1.015 | 0.08 |
| 580_T | 596_T | 1.015 | 0.08 |
| 145_K | 150_G | 1.015 | 0.08 |
| 163_K | 547_N | 1.013 | 0.08 |
| 149_D | 171_G | 1.013 | 0.08 |
| 249_Q | 374_N | 1.013 | 0.08 |
| 507_T | 580_T | 1.013 | 0.08 |
| 127_Q | 130_V | 1.010 | 0.08 |
| 285_G | 391_V | 1.010 | 0.08 |
| 545_A | 661_A | 1.010 | 0.08 |
| 79_D | 174_V | 1.009 | 0.08 |
| 345_I | 682_A | 1.008 | 0.08 |
| 372_A | 485_M | 1.008 | 0.08 |
| 177_Y | 282_V | 1.008 | 0.08 |
| 22_I | 716_I | 1.008 | 0.08 |
| 568_L | 756_Q | 1.006 | 0.08 |
| 171_G | 213_E | 1.006 | 0.08 |
| 70_Q | 646_S | 1.006 | 0.08 |
| 168_M | 189_Y | 1.006 | 0.08 |
| 547_N | 645_K | 1.006 | 0.08 |
| 657_I | 755_N | 1.005 | 0.08 |
| 213_E | 605_T | 1.005 | 0.08 |
| 76_P | 226_P | 1.003 | 0.08 |
| 16_V | 659_T | 1.003 | 0.08 |
| 420_S | 662_S | 1.003 | 0.08 |
| 415_F | 673_V | 1.002 | 0.08 |
| 118_N | 174_V | 1.002 | 0.08 |
| 436_P | 461_F | 1.001 | 0.08 |
| 18_I | 629_L | 1.001 | 0.08 |
| 255_I | 743_L | 1.001 | 0.08 |
| 165_Y | 218_E | 1.001 | 0.08 |
| 226_P | 592_T | 1.001 | 0.08 |
Prob = P(contact | scaled_score, seq/len).
Scaled Score = (raw_score/average(raw_scores)).
- Text file of contact predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
- Import to GREMLIN BETA - features includes ability to upload PDB and latest P(contact) calculation based on eLife 2015 fitting to PDB data.
GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled Score > 1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-position alignment confidence. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | M | Cov | P(%) | HHΔ | |
| 3iyuX | 3 | 0.9509 | 100 | 0.057 | Contact Map |
| 1slqA | 6 | 0.3514 | 100 | 0.589 | Contact Map |
| 2b4hA | 2 | 0.2933 | 100 | 0.659 | Contact Map |
| 1kqrA | 1 | 0.2067 | 100 | 0.844 | Contact Map |
| 2aenA | 8 | 0.2119 | 100 | 0.852 | Contact Map |
| 4drrA | 1 | 0.2106 | 100 | 0.854 | Contact Map |
| 2gboA | 2 | 0.0478 | 55.2 | 0.991 | Contact Map |
| 4fp9B | 4 | 0.1098 | 44.9 | 0.991 | Contact Map |
| 3i5cA | 2 | 0.1537 | 43.3 | 0.991 | Contact Map |
| 4j40A | 2 | 0 | 40.8 | 0.991 | Contact Map |
Cov = coverage of hit
P(%) = probability
Sequence Conservation (Image Generated using WebLogo v3)