| endTGAC ks at |
| ID: | 1509394673 |
Query Sequence |
Download Alignment We filter this alignment to remove positions that have > 75% gaps before running GREMLIN. |
| Length: | 844 (844) | ||
| Sequences: | 8245 (6481.1) | ||
| Seq/Len: | 9.769 | ||
| Nf(neff/√len): | 223.1 |
HHblits Results: (2016_02)
Sequences per length for each position, BEFORE the coverage/gap filter was applied
Legend: Dots above the red line, indicates positions where there is > 5 sequences per length (if visible, green bar = 20 seq/len). Point of this graphic is to give you an idea if resubmitting a sub-portion of your sequence might help increase the overall Seq/Len (which after applying the coverage filter is at: 9.769).
Sequences per length for each position, AFTER the coverage/gap filter was applied
Residue pairs sorted by coevolution strength:
Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] covarying residues with sequence seperation > 3. The i and j are positions as given in the input sequence.
| i | j | Scaled score | Prob |
| 229_A | 379_P | 4.448 | 1.00 |
| 157_S | 166_S | 3.397 | 1.00 |
| 25_R | 29_A | 3.164 | 1.00 |
| 657_I | 701_L | 3.042 | 1.00 |
| 769_R | 773_Q | 3.028 | 1.00 |
| 776_R | 779_D | 2.998 | 1.00 |
| 545_L | 556_E | 2.973 | 1.00 |
| 180_L | 356_V | 2.903 | 1.00 |
| 260_A | 360_A | 2.901 | 1.00 |
| 698_E | 713_R | 2.884 | 1.00 |
| 247_R | 250_D | 2.864 | 1.00 |
| 101_A | 244_V | 2.708 | 1.00 |
| 368_V | 391_P | 2.696 | 1.00 |
| 23_L | 340_I | 2.695 | 1.00 |
| 18_D | 22_A | 2.691 | 1.00 |
| 123_M | 152_A | 2.690 | 1.00 |
| 227_F | 307_A | 2.680 | 1.00 |
| 678_A | 723_A | 2.672 | 1.00 |
| 246_K | 256_D | 2.611 | 1.00 |
| 116_Q | 193_D | 2.578 | 1.00 |
| 751_T | 780_A | 2.569 | 1.00 |
| 733_L | 765_A | 2.554 | 1.00 |
| 693_E | 724_Q | 2.546 | 1.00 |
| 2_E | 249_S | 2.544 | 1.00 |
| 98_A | 196_L | 2.523 | 1.00 |
| 2_E | 5_A | 2.522 | 1.00 |
| 221_D | 232_D | 2.506 | 1.00 |
| 26_L | 33_A | 2.476 | 1.00 |
| 602_A | 605_R | 2.467 | 1.00 |
| 79_V | 87_M | 2.466 | 1.00 |
| 493_A | 499_L | 2.458 | 1.00 |
| 655_A | 697_V | 2.450 | 1.00 |
| 226_S | 342_S | 2.450 | 1.00 |
| 340_I | 354_A | 2.438 | 1.00 |
| 97_T | 240_A | 2.432 | 1.00 |
| 259_L | 364_R | 2.426 | 1.00 |
| 120_F | 186_S | 2.408 | 1.00 |
| 605_R | 610_E | 2.361 | 1.00 |
| 241_G | 353_L | 2.355 | 1.00 |
| 460_R | 504_D | 2.353 | 1.00 |
| 186_S | 192_C | 2.345 | 1.00 |
| 555_I | 595_A | 2.336 | 1.00 |
| 464_D | 504_D | 2.333 | 1.00 |
| 49_D | 54_A | 2.330 | 1.00 |
| 184_C | 262_V | 2.318 | 1.00 |
| 285_E | 325_A | 2.300 | 1.00 |
| 36_E | 62_R | 2.281 | 1.00 |
| 736_L | 741_P | 2.275 | 1.00 |
| 19_D | 22_A | 2.246 | 1.00 |
| 442_L | 499_L | 2.222 | 1.00 |
| 726_E | 772_R | 2.217 | 1.00 |
| 530_F | 601_S | 2.217 | 1.00 |
| 402_L | 420_E | 2.212 | 1.00 |
| 367_T | 394_A | 2.202 | 1.00 |
| 229_A | 376_A | 2.199 | 1.00 |
| 243_L | 356_V | 2.195 | 1.00 |
| 6_I | 360_A | 2.193 | 1.00 |
| 559_A | 569_S | 2.186 | 1.00 |
| 543_A | 827_G | 2.161 | 1.00 |
| 219_A | 225_K | 2.156 | 1.00 |
| 632_S | 635_D | 2.149 | 1.00 |
| 473_D | 476_C | 2.131 | 1.00 |
| 604_W | 821_S | 2.114 | 1.00 |
| 389_E | 395_R | 2.108 | 1.00 |
| 246_K | 254_A | 2.102 | 1.00 |
| 263_R | 420_E | 2.095 | 1.00 |
| 54_A | 57_K | 2.095 | 1.00 |
| 669_R | 707_A | 2.093 | 1.00 |
| 601_S | 627_V | 2.087 | 1.00 |
| 230_A | 375_E | 2.077 | 1.00 |
| 496_R | 500_L | 2.064 | 1.00 |
| 555_I | 574_L | 2.063 | 1.00 |
| 663_A | 667_G | 2.057 | 1.00 |
| 362_A | 369_P | 2.050 | 1.00 |
| 320_A | 337_V | 2.044 | 1.00 |
| 662_P | 665_E | 2.039 | 1.00 |
| 691_A | 722_C | 2.018 | 1.00 |
| 442_L | 493_A | 2.007 | 1.00 |
| 785_L | 809_F | 2.000 | 1.00 |
| 181_H | 265_S | 1.995 | 1.00 |
| 371_N | 374_A | 1.992 | 1.00 |
| 27_L | 361_L | 1.990 | 1.00 |
| 304_Y | 368_V | 1.986 | 1.00 |
| 359_A | 403_A | 1.978 | 1.00 |
| 266_A | 291_A | 1.964 | 1.00 |
| 366_R | 401_R | 1.963 | 1.00 |
| 10_G | 97_T | 1.962 | 1.00 |
| 473_D | 477_S | 1.954 | 1.00 |
| 382_P | 385_A | 1.941 | 1.00 |
| 446_G | 452_L | 1.934 | 1.00 |
| 265_S | 417_V | 1.930 | 1.00 |
| 690_V | 700_L | 1.925 | 1.00 |
| 639_V | 736_L | 1.920 | 1.00 |
| 153_S | 168_T | 1.916 | 1.00 |
| 237_S | 347_T | 1.910 | 1.00 |
| 778_L | 782_Q | 1.905 | 1.00 |
| 659_V | 666_L | 1.887 | 1.00 |
| 344_L | 354_A | 1.874 | 1.00 |
| 250_D | 253_A | 1.859 | 1.00 |
| 495_D | 498_A | 1.858 | 1.00 |
| 94_L | 156_L | 1.855 | 1.00 |
| 68_D | 71_R | 1.850 | 1.00 |
| 34_T | 64_G | 1.843 | 1.00 |
| 21_E | 104_Q | 1.837 | 1.00 |
| 98_A | 242_V | 1.832 | 1.00 |
| 494_R | 498_A | 1.832 | 1.00 |
| 677_L | 700_L | 1.831 | 1.00 |
| 102_L | 244_V | 1.826 | 1.00 |
| 228_S | 374_A | 1.824 | 1.00 |
| 6_I | 356_V | 1.824 | 1.00 |
| 43_D | 46_A | 1.823 | 1.00 |
| 178_V | 415_A | 1.821 | 1.00 |
| 13_F | 354_A | 1.813 | 1.00 |
| 336_V | 395_R | 1.813 | 1.00 |
| 477_S | 481_T | 1.805 | 1.00 |
| 180_L | 245_V | 1.804 | 1.00 |
| 28_L | 367_T | 1.787 | 1.00 |
| 526_V | 612_D | 1.785 | 1.00 |
| 32_D | 223_R | 1.783 | 1.00 |
| 221_D | 225_K | 1.777 | 1.00 |
| 527_V | 789_H | 1.775 | 1.00 |
| 8_G | 104_Q | 1.761 | 1.00 |
| 649_R | 731_E | 1.758 | 1.00 |
| 561_A | 637_A | 1.755 | 1.00 |
| 342_S | 372_L | 1.754 | 1.00 |
| 336_V | 391_P | 1.748 | 1.00 |
| 185_Q | 294_L | 1.745 | 1.00 |
| 185_Q | 189_A | 1.743 | 1.00 |
| 676_R | 693_E | 1.742 | 1.00 |
| 370_A | 394_A | 1.739 | 1.00 |
| 228_S | 375_E | 1.738 | 1.00 |
| 102_L | 160_L | 1.737 | 1.00 |
| 22_A | 25_R | 1.736 | 1.00 |
| 180_L | 197_V | 1.728 | 1.00 |
| 116_Q | 290_R | 1.710 | 1.00 |
| 171_T | 174_S | 1.706 | 1.00 |
| 3_P | 263_R | 1.701 | 1.00 |
| 548_S | 603_L | 1.697 | 1.00 |
| 536_Q | 540_M | 1.689 | 1.00 |
| 701_L | 705_Q | 1.688 | 1.00 |
| 342_S | 371_N | 1.685 | 1.00 |
| 367_T | 396_A | 1.674 | 1.00 |
| 94_L | 152_A | 1.673 | 1.00 |
| 399_D | 421_R | 1.671 | 1.00 |
| 336_V | 389_E | 1.671 | 1.00 |
| 259_L | 360_A | 1.666 | 1.00 |
| 751_T | 770_N | 1.664 | 1.00 |
| 615_I | 780_A | 1.663 | 1.00 |
| 596_V | 822_L | 1.655 | 1.00 |
| 626_C | 636_A | 1.652 | 1.00 |
| 805_L | 818_V | 1.644 | 1.00 |
| 663_A | 776_R | 1.644 | 1.00 |
| 554_R | 557_A | 1.639 | 1.00 |
| 447_R | 485_F | 1.639 | 1.00 |
| 798_H | 824_R | 1.635 | 1.00 |
| 529_V | 805_L | 1.628 | 1.00 |
| 366_R | 421_R | 1.627 | 1.00 |
| 555_I | 599_S | 1.615 | 1.00 |
| 701_L | 713_R | 1.603 | 1.00 |
| 378_H | 381_I | 1.601 | 1.00 |
| 94_L | 121_V | 1.600 | 1.00 |
| 121_V | 198_G | 1.599 | 1.00 |
| 594_F | 636_A | 1.590 | 1.00 |
| 180_L | 417_V | 1.589 | 1.00 |
| 661_L | 666_L | 1.585 | 1.00 |
| 464_D | 500_L | 1.585 | 1.00 |
| 603_L | 606_S | 1.583 | 1.00 |
| 455_Q | 459_L | 1.580 | 1.00 |
| 552_R | 556_E | 1.580 | 1.00 |
| 659_V | 704_L | 1.578 | 1.00 |
| 243_L | 353_L | 1.571 | 1.00 |
| 359_A | 363_L | 1.571 | 1.00 |
| 607_M | 832_F | 1.570 | 1.00 |
| 733_L | 768_Y | 1.570 | 1.00 |
| 462_H | 466_H | 1.569 | 1.00 |
| 336_V | 368_V | 1.565 | 1.00 |
| 304_Y | 359_A | 1.560 | 1.00 |
| 660_D | 710_V | 1.558 | 1.00 |
| 657_I | 697_V | 1.552 | 1.00 |
| 287_V | 291_A | 1.545 | 1.00 |
| 558_C | 633_L | 1.538 | 1.00 |
| 557_A | 634_D | 1.538 | 1.00 |
| 459_L | 478_L | 1.538 | 1.00 |
| 163_H | 286_A | 1.538 | 1.00 |
| 17_A | 26_L | 1.537 | 1.00 |
| 35_R | 67_E | 1.536 | 1.00 |
| 749_Y | 756_R | 1.534 | 1.00 |
| 559_A | 563_E | 1.534 | 1.00 |
| 401_R | 421_R | 1.532 | 1.00 |
| 694_K | 698_E | 1.527 | 1.00 |
| 110_E | 483_T | 1.515 | 1.00 |
| 181_H | 191_E | 1.498 | 1.00 |
| 104_Q | 257_S | 1.496 | 1.00 |
| 178_V | 413_T | 1.489 | 1.00 |
| 561_A | 634_D | 1.488 | 1.00 |
| 460_R | 500_L | 1.486 | 1.00 |
| 64_G | 237_S | 1.483 | 1.00 |
| 356_V | 419_L | 1.482 | 1.00 |
| 241_G | 357_L | 1.479 | 1.00 |
| 104_Q | 259_L | 1.475 | 1.00 |
| 489_A | 506_L | 1.472 | 1.00 |
| 557_A | 602_A | 1.472 | 1.00 |
| 154_G | 411_S | 1.467 | 1.00 |
| 17_A | 22_A | 1.466 | 1.00 |
| 525_K | 612_D | 1.447 | 1.00 |
| 327_Y | 404_G | 1.446 | 1.00 |
| 397_W | 401_R | 1.445 | 1.00 |
| 556_E | 571_L | 1.438 | 1.00 |
| 225_K | 232_D | 1.437 | 1.00 |
| 442_L | 471_L | 1.432 | 1.00 |
| 305_V | 323_L | 1.429 | 1.00 |
| 460_R | 464_D | 1.427 | 1.00 |
| 151_V | 276_L | 1.427 | 1.00 |
| 484_H | 840_W | 1.425 | 1.00 |
| 669_R | 704_L | 1.417 | 1.00 |
| 363_L | 419_L | 1.415 | 0.99 |
| 455_Q | 458_K | 1.413 | 0.99 |
| 285_E | 289_R | 1.405 | 0.99 |
| 749_Y | 787_D | 1.405 | 0.99 |
| 40_D | 70_D | 1.404 | 0.99 |
| 791_F | 844_F | 1.403 | 0.99 |
| 290_R | 294_L | 1.400 | 0.99 |
| 665_E | 709_V | 1.399 | 0.99 |
| 186_S | 191_E | 1.398 | 0.99 |
| 113_R | 161_G | 1.398 | 0.99 |
| 749_Y | 783_R | 1.394 | 0.99 |
| 665_E | 668_E | 1.385 | 0.99 |
| 703_E | 707_A | 1.385 | 0.99 |
| 180_L | 262_V | 1.382 | 0.99 |
| 324_G | 386_L | 1.381 | 0.99 |
| 13_F | 241_G | 1.380 | 0.99 |
| 447_R | 486_A | 1.374 | 0.99 |
| 4_I | 245_V | 1.372 | 0.99 |
| 642_R | 645_R | 1.370 | 0.99 |
| 733_L | 737_A | 1.363 | 0.99 |
| 220_P | 232_D | 1.357 | 0.99 |
| 26_L | 31_T | 1.353 | 0.99 |
| 528_F | 611_P | 1.352 | 0.99 |
| 562_L | 641_A | 1.351 | 0.99 |
| 187_L | 247_R | 1.350 | 0.99 |
| 694_K | 713_R | 1.348 | 0.99 |
| 585_R | 648_T | 1.348 | 0.99 |
| 32_D | 373_H | 1.346 | 0.99 |
| 731_E | 734_D | 1.345 | 0.99 |
| 76_F | 485_F | 1.345 | 0.99 |
| 781_V | 805_L | 1.342 | 0.99 |
| 196_L | 244_V | 1.339 | 0.99 |
| 839_L | 844_F | 1.339 | 0.99 |
| 527_V | 784_L | 1.338 | 0.99 |
| 564_R | 634_D | 1.338 | 0.99 |
| 663_A | 682_V | 1.331 | 0.99 |
| 301_H | 402_L | 1.331 | 0.99 |
| 11_C | 20_P | 1.328 | 0.99 |
| 49_D | 57_K | 1.324 | 0.99 |
| 559_A | 571_L | 1.323 | 0.99 |
| 34_T | 62_R | 1.322 | 0.99 |
| 193_D | 247_R | 1.319 | 0.99 |
| 374_A | 390_L | 1.316 | 0.99 |
| 444_L | 456_A | 1.315 | 0.99 |
| 655_A | 694_K | 1.314 | 0.99 |
| 52_A | 216_R | 1.310 | 0.99 |
| 598_V | 623_A | 1.307 | 0.99 |
| 169_I | 182_L | 1.302 | 0.99 |
| 274_A | 278_A | 1.299 | 0.99 |
| 266_A | 287_V | 1.292 | 0.99 |
| 248_L | 261_V | 1.288 | 0.99 |
| 25_R | 31_T | 1.288 | 0.99 |
| 587_D | 648_T | 1.285 | 0.99 |
| 187_L | 250_D | 1.282 | 0.99 |
| 475_A | 478_L | 1.279 | 0.99 |
| 101_A | 242_V | 1.274 | 0.99 |
| 562_L | 637_A | 1.274 | 0.99 |
| 449_G | 487_R | 1.274 | 0.99 |
| 383_W | 390_L | 1.269 | 0.99 |
| 366_R | 399_D | 1.267 | 0.99 |
| 470_A | 473_D | 1.267 | 0.99 |
| 298_E | 301_H | 1.266 | 0.99 |
| 757_L | 761_E | 1.265 | 0.99 |
| 198_G | 242_V | 1.263 | 0.99 |
| 587_D | 591_P | 1.261 | 0.99 |
| 682_V | 688_T | 1.260 | 0.99 |
| 554_R | 602_A | 1.259 | 0.99 |
| 728_L | 771_M | 1.257 | 0.99 |
| 98_A | 160_L | 1.256 | 0.99 |
| 493_A | 498_A | 1.255 | 0.99 |
| 297_V | 301_H | 1.251 | 0.98 |
| 491_V | 502_A | 1.250 | 0.98 |
| 702_R | 705_Q | 1.249 | 0.98 |
| 698_E | 702_R | 1.246 | 0.98 |
| 553_E | 557_A | 1.244 | 0.98 |
| 821_S | 835_S | 1.244 | 0.98 |
| 613_A | 789_H | 1.243 | 0.98 |
| 525_K | 790_R | 1.243 | 0.98 |
| 765_A | 769_R | 1.235 | 0.98 |
| 448_T | 487_R | 1.230 | 0.98 |
| 638_M | 738_G | 1.228 | 0.98 |
| 693_E | 696_A | 1.227 | 0.98 |
| 442_L | 478_L | 1.222 | 0.98 |
| 802_L | 818_V | 1.221 | 0.98 |
| 118_G | 192_C | 1.218 | 0.98 |
| 9_A | 357_L | 1.218 | 0.98 |
| 603_L | 832_F | 1.211 | 0.98 |
| 819_V | 835_S | 1.210 | 0.98 |
| 555_I | 571_L | 1.207 | 0.98 |
| 118_G | 165_P | 1.207 | 0.98 |
| 490_A | 837_S | 1.205 | 0.98 |
| 121_V | 156_L | 1.202 | 0.98 |
| 781_V | 808_T | 1.199 | 0.98 |
| 729_R | 768_Y | 1.197 | 0.98 |
| 586_I | 720_T | 1.195 | 0.98 |
| 121_V | 242_V | 1.188 | 0.98 |
| 347_T | 354_A | 1.188 | 0.98 |
| 313_R | 380_D | 1.187 | 0.98 |
| 377_P | 383_W | 1.185 | 0.98 |
| 726_E | 768_Y | 1.184 | 0.98 |
| 659_V | 690_V | 1.184 | 0.98 |
| 603_L | 607_M | 1.183 | 0.98 |
| 126_S | 149_G | 1.181 | 0.98 |
| 530_F | 627_V | 1.181 | 0.98 |
| 361_L | 365_H | 1.180 | 0.98 |
| 28_L | 394_A | 1.179 | 0.98 |
| 93_L | 240_A | 1.178 | 0.98 |
| 545_L | 555_I | 1.175 | 0.97 |
| 748_L | 762_L | 1.174 | 0.97 |
| 59_T | 216_R | 1.173 | 0.97 |
| 194_T | 244_V | 1.170 | 0.97 |
| 167_I | 182_L | 1.170 | 0.97 |
| 731_E | 735_R | 1.168 | 0.97 |
| 476_C | 480_G | 1.168 | 0.97 |
| 543_A | 547_S | 1.167 | 0.97 |
| 528_F | 795_V | 1.164 | 0.97 |
| 664_A | 667_G | 1.162 | 0.97 |
| 183_A | 195_A | 1.157 | 0.97 |
| 680_A | 691_A | 1.156 | 0.97 |
| 666_L | 670_L | 1.155 | 0.97 |
| 127_D | 131_A | 1.149 | 0.97 |
| 729_R | 733_L | 1.148 | 0.97 |
| 94_L | 242_V | 1.146 | 0.97 |
| 677_L | 690_V | 1.140 | 0.97 |
| 792_F | 805_L | 1.140 | 0.97 |
| 666_L | 688_T | 1.139 | 0.97 |
| 297_V | 402_L | 1.137 | 0.97 |
| 752_V | 773_Q | 1.137 | 0.97 |
| 197_V | 353_L | 1.136 | 0.97 |
| 550_V | 606_S | 1.135 | 0.97 |
| 404_G | 416_H | 1.133 | 0.97 |
| 98_A | 156_L | 1.132 | 0.97 |
| 181_H | 185_Q | 1.130 | 0.97 |
| 98_A | 101_A | 1.129 | 0.97 |
| 228_S | 376_A | 1.129 | 0.97 |
| 102_L | 112_L | 1.127 | 0.96 |
| 268_N | 414_N | 1.125 | 0.96 |
| 729_R | 772_R | 1.124 | 0.96 |
| 457_A | 461_A | 1.124 | 0.96 |
| 704_L | 709_V | 1.123 | 0.96 |
| 747_P | 756_R | 1.121 | 0.96 |
| 724_Q | 727_V | 1.120 | 0.96 |
| 4_I | 184_C | 1.118 | 0.96 |
| 225_K | 230_A | 1.113 | 0.96 |
| 446_G | 451_A | 1.111 | 0.96 |
| 545_L | 575_R | 1.110 | 0.96 |
| 527_V | 792_F | 1.109 | 0.96 |
| 441_P | 837_S | 1.107 | 0.96 |
| 196_L | 242_V | 1.106 | 0.96 |
| 34_T | 235_G | 1.105 | 0.96 |
| 543_A | 828_D | 1.103 | 0.96 |
| 646_L | 728_L | 1.103 | 0.96 |
| 199_S | 353_L | 1.102 | 0.96 |
| 582_S | 585_R | 1.101 | 0.96 |
| 12_R | 100_E | 1.101 | 0.96 |
| 236_W | 348_Q | 1.101 | 0.96 |
| 542_K | 546_E | 1.098 | 0.96 |
| 666_L | 690_V | 1.097 | 0.96 |
| 830_R | 834_L | 1.096 | 0.96 |
| 257_S | 364_R | 1.095 | 0.96 |
| 701_L | 711_A | 1.093 | 0.96 |
| 123_M | 168_T | 1.092 | 0.96 |
| 528_F | 609_V | 1.089 | 0.96 |
| 363_L | 366_R | 1.088 | 0.95 |
| 197_V | 245_V | 1.086 | 0.95 |
| 108_V | 483_T | 1.085 | 0.95 |
| 755_D | 783_R | 1.085 | 0.95 |
| 614_V | 748_L | 1.082 | 0.95 |
| 615_I | 784_L | 1.081 | 0.95 |
| 443_V | 479_A | 1.080 | 0.95 |
| 25_R | 28_L | 1.080 | 0.95 |
| 280_N | 283_A | 1.079 | 0.95 |
| 185_Q | 188_R | 1.078 | 0.95 |
| 182_L | 185_Q | 1.078 | 0.95 |
| 108_V | 111_R | 1.077 | 0.95 |
| 793_V | 839_L | 1.075 | 0.95 |
| 498_A | 502_A | 1.073 | 0.95 |
| 292_L | 327_Y | 1.072 | 0.95 |
| 122_G | 175_S | 1.072 | 0.95 |
| 622_I | 736_L | 1.071 | 0.95 |
| 604_W | 795_V | 1.070 | 0.95 |
| 698_E | 701_L | 1.070 | 0.95 |
| 548_S | 607_M | 1.070 | 0.95 |
| 178_V | 267_V | 1.070 | 0.95 |
| 363_L | 422_A | 1.069 | 0.95 |
| 363_L | 421_R | 1.067 | 0.95 |
| 37_V | 209_F | 1.066 | 0.95 |
| 48_Y | 61_R | 1.065 | 0.95 |
| 602_A | 626_C | 1.064 | 0.95 |
| 494_R | 830_R | 1.059 | 0.95 |
| 264_A | 294_L | 1.056 | 0.94 |
| 826_E | 831_R | 1.055 | 0.94 |
| 598_V | 626_C | 1.052 | 0.94 |
| 36_E | 61_R | 1.051 | 0.94 |
| 252_L | 425_P | 1.050 | 0.94 |
| 539_H | 542_K | 1.050 | 0.94 |
| 9_A | 20_P | 1.049 | 0.94 |
| 526_V | 791_F | 1.049 | 0.94 |
| 498_A | 830_R | 1.049 | 0.94 |
| 99_W | 103_E | 1.048 | 0.94 |
| 154_G | 166_S | 1.048 | 0.94 |
| 657_I | 711_A | 1.048 | 0.94 |
| 38_P | 41_R | 1.048 | 0.94 |
| 192_C | 195_A | 1.048 | 0.94 |
| 123_M | 149_G | 1.046 | 0.94 |
| 230_A | 374_A | 1.043 | 0.94 |
| 559_A | 570_P | 1.039 | 0.94 |
| 676_R | 696_A | 1.038 | 0.94 |
| 443_V | 840_W | 1.036 | 0.94 |
| 262_V | 417_V | 1.026 | 0.93 |
| 374_A | 377_P | 1.023 | 0.93 |
| 176_A | 353_L | 1.022 | 0.93 |
| 607_M | 836_L | 1.021 | 0.93 |
| 288_L | 326_V | 1.021 | 0.93 |
| 630_A | 744_S | 1.019 | 0.93 |
| 561_A | 565_H | 1.018 | 0.93 |
| 442_L | 475_A | 1.018 | 0.93 |
| 320_A | 381_I | 1.014 | 0.93 |
| 558_C | 637_A | 1.012 | 0.93 |
| 594_F | 598_V | 1.009 | 0.92 |
| 441_P | 490_A | 1.004 | 0.92 |
| 278_A | 314_L | 1.004 | 0.92 |
| 500_L | 504_D | 1.002 | 0.92 |
| 526_V | 844_F | 1.002 | 0.92 |
| 454_A | 457_A | 1.001 | 0.92 |
| 444_L | 459_L | 1.001 | 0.92 |
| 69_I | 204_L | 1.001 | 0.92 |
Prob = P(contact | scaled_score, seq/len).
Scaled Score = (raw_score/average(raw_scores)).
- Text file of contact predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
- Import to GREMLIN BETA - features includes ability to upload PDB and latest P(contact) calculation based on eLife 2015 fitting to PDB data.
GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled Score > 1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-position alignment confidence. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | M | Cov | P(%) | HHΔ | |
| 2vz8A | 2 | 0.9431 | 100 | 0.096 | Contact Map |
| 4mz0A | 2 | 0.9716 | 100 | 0.12 | Contact Map |
| 2qo3A | 2 | 0.987 | 100 | 0.122 | Contact Map |
| 2hg4A | 6 | 0.968 | 100 | 0.13 | Contact Map |
| 3hhdA | 4 | 0.9431 | 100 | 0.18 | Contact Map |
| 4oqjA | 1 | 0.7844 | 100 | 0.353 | Contact Map |
| 4na1A | 2 | 0.6742 | 100 | 0.393 | Contact Map |
| 4tktA | 1 | 0.6623 | 100 | 0.394 | Contact Map |
| 4opeA | 4 | 0.6611 | 100 | 0.42 | Contact Map |
| 4zdnA | 1 | 0 | 100 | 0.422 | Contact Map |
Cov = coverage of hit
P(%) = probability
Sequence Conservation (Image Generated using WebLogo v3)