| at and kr |
| ID: | 1509389761 |
Query Sequence |
Download Alignment We filter this alignment to remove positions that have > 75% gaps before running GREMLIN. |
| Length: | 837 (837) | ||
| Sequences: | 4486 (3896.3) | ||
| Seq/Len: | 5.360 | ||
| Nf(neff/√len): | 134.7 |
HHblits Results: (2016_02)
Sequences per length for each position, BEFORE the coverage/gap filter was applied
Legend: Dots above the red line, indicates positions where there is > 5 sequences per length (if visible, green bar = 20 seq/len). Point of this graphic is to give you an idea if resubmitting a sub-portion of your sequence might help increase the overall Seq/Len (which after applying the coverage filter is at: 5.360).
Sequences per length for each position, AFTER the coverage/gap filter was applied
Residue pairs sorted by coevolution strength:
Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] covarying residues with sequence seperation > 3. The i and j are positions as given in the input sequence.
| i | j | Scaled score | Prob |
| 688_T | 728_L | 4.043 | 1.00 |
| 790_L | 817_A | 3.743 | 1.00 |
| 741_A | 787_A | 3.460 | 1.00 |
| 242_R | 246_Q | 3.450 | 1.00 |
| 249_R | 252_D | 3.353 | 1.00 |
| 166_E | 197_Q | 3.342 | 1.00 |
| 224_T | 253_A | 3.337 | 1.00 |
| 130_A | 174_L | 3.274 | 1.00 |
| 675_R | 704_E | 3.266 | 1.00 |
| 750_Q | 761_E | 3.123 | 1.00 |
| 18_L | 29_E | 3.070 | 1.00 |
| 209_L | 214_A | 3.062 | 1.00 |
| 128_A | 170_I | 2.966 | 1.00 |
| 722_R | 778_E | 2.943 | 1.00 |
| 28_I | 47_L | 2.791 | 1.00 |
| 78_R | 83_E | 2.772 | 1.00 |
| 774_R | 812_F | 2.766 | 1.00 |
| 673_V | 791_F | 2.702 | 1.00 |
| 777_H | 819_H | 2.667 | 1.00 |
| 171_D | 186_K | 2.664 | 1.00 |
| 151_A | 196_A | 2.629 | 1.00 |
| 774_R | 777_H | 2.583 | 1.00 |
| 206_L | 238_A | 2.574 | 1.00 |
| 75_A | 78_R | 2.555 | 1.00 |
| 773_A | 816_L | 2.452 | 1.00 |
| 258_L | 282_A | 2.392 | 1.00 |
| 16_A | 300_G | 2.388 | 1.00 |
| 34_A | 110_A | 2.376 | 1.00 |
| 721_D | 724_A | 2.333 | 1.00 |
| 99_C | 109_A | 2.322 | 1.00 |
| 819_H | 823_L | 2.312 | 1.00 |
| 77_W | 294_S | 2.308 | 1.00 |
| 251_A | 255_R | 2.284 | 1.00 |
| 729_L | 779_L | 2.250 | 1.00 |
| 684_R | 711_R | 2.247 | 1.00 |
| 142_R | 180_A | 2.235 | 1.00 |
| 88_V | 253_A | 2.225 | 1.00 |
| 725_L | 775_H | 2.187 | 1.00 |
| 28_I | 68_A | 2.172 | 1.00 |
| 224_T | 243_N | 2.167 | 1.00 |
| 725_L | 728_L | 2.135 | 1.00 |
| 722_R | 779_L | 2.110 | 1.00 |
| 149_R | 166_E | 2.102 | 1.00 |
| 136_A | 140_E | 2.093 | 1.00 |
| 278_L | 291_V | 2.077 | 1.00 |
| 625_D | 639_R | 2.075 | 1.00 |
| 817_A | 827_A | 2.074 | 1.00 |
| 112_V | 209_L | 2.039 | 1.00 |
| 27_Q | 30_A | 2.024 | 1.00 |
| 130_A | 170_I | 2.020 | 1.00 |
| 76_L | 79_A | 2.010 | 1.00 |
| 164_S | 195_C | 2.010 | 1.00 |
| 719_T | 725_L | 1.983 | 1.00 |
| 76_L | 305_L | 1.964 | 1.00 |
| 105_S | 108_D | 1.959 | 1.00 |
| 264_F | 317_L | 1.956 | 1.00 |
| 660_V | 741_A | 1.941 | 1.00 |
| 752_A | 761_E | 1.927 | 1.00 |
| 67_F | 109_A | 1.926 | 1.00 |
| 199_E | 245_R | 1.925 | 1.00 |
| 69_V | 295_L | 1.917 | 1.00 |
| 781_G | 823_L | 1.909 | 1.00 |
| 581_A | 815_A | 1.906 | 1.00 |
| 702_V | 714_V | 1.900 | 1.00 |
| 415_W | 418_R | 1.899 | 1.00 |
| 32_A | 42_P | 1.890 | 1.00 |
| 222_Y | 260_D | 1.889 | 1.00 |
| 757_T | 805_G | 1.884 | 1.00 |
| 719_T | 772_G | 1.868 | 1.00 |
| 132_A | 139_I | 1.861 | 1.00 |
| 814_D | 829_S | 1.841 | 1.00 |
| 138_E | 182_V | 1.836 | 1.00 |
| 142_R | 177_L | 1.819 | 1.00 |
| 26_G | 30_A | 1.818 | 1.00 |
| 132_A | 177_L | 1.816 | 1.00 |
| 150_L | 173_L | 1.815 | 1.00 |
| 222_Y | 229_R | 1.812 | 1.00 |
| 777_H | 820_R | 1.810 | 1.00 |
| 365_F | 369_V | 1.806 | 1.00 |
| 136_A | 249_R | 1.803 | 1.00 |
| 684_R | 713_T | 1.799 | 1.00 |
| 197_Q | 200_A | 1.794 | 1.00 |
| 134_L | 139_I | 1.791 | 1.00 |
| 725_L | 779_L | 1.777 | 1.00 |
| 740_R | 786_D | 1.772 | 1.00 |
| 739_L | 780_L | 1.770 | 1.00 |
| 35_L | 114_A | 1.762 | 1.00 |
| 122_R | 204_E | 1.755 | 1.00 |
| 584_W | 627_Q | 1.750 | 1.00 |
| 176_E | 180_A | 1.746 | 1.00 |
| 32_A | 44_L | 1.738 | 1.00 |
| 133_E | 183_F | 1.734 | 1.00 |
| 777_H | 825_L | 1.731 | 1.00 |
| 60_D | 64_P | 1.730 | 1.00 |
| 658_G | 740_R | 1.707 | 1.00 |
| 806_Y | 810_N | 1.705 | 1.00 |
| 578_P | 582_L | 1.704 | 1.00 |
| 678_A | 710_A | 1.704 | 1.00 |
| 3_F | 74_A | 1.686 | 1.00 |
| 630_L | 635_L | 1.681 | 1.00 |
| 135_P | 138_E | 1.677 | 1.00 |
| 310_C | 314_T | 1.669 | 1.00 |
| 95_I | 209_L | 1.661 | 0.99 |
| 544_L | 548_Q | 1.647 | 0.99 |
| 201_V | 244_L | 1.644 | 0.99 |
| 706_T | 712_V | 1.633 | 0.99 |
| 59_V | 193_S | 1.627 | 0.99 |
| 86_A | 262_H | 1.625 | 0.99 |
| 21_S | 76_L | 1.617 | 0.99 |
| 199_E | 241_V | 1.607 | 0.99 |
| 28_I | 72_S | 1.606 | 0.99 |
| 591_A | 627_Q | 1.595 | 0.99 |
| 30_A | 107_E | 1.588 | 0.99 |
| 732_L | 739_L | 1.584 | 0.99 |
| 820_R | 825_L | 1.583 | 0.99 |
| 175_R | 178_D | 1.574 | 0.99 |
| 163_V | 173_L | 1.571 | 0.99 |
| 312_L | 317_L | 1.568 | 0.99 |
| 35_L | 110_A | 1.568 | 0.99 |
| 2_V | 278_L | 1.567 | 0.99 |
| 363_S | 366_W | 1.561 | 0.99 |
| 167_P | 171_D | 1.558 | 0.99 |
| 702_V | 712_V | 1.555 | 0.99 |
| 665_G | 714_V | 1.553 | 0.99 |
| 25_R | 29_E | 1.553 | 0.99 |
| 366_W | 369_V | 1.549 | 0.99 |
| 271_H | 297_R | 1.548 | 0.99 |
| 230_I | 234_A | 1.544 | 0.99 |
| 775_H | 779_L | 1.538 | 0.99 |
| 563_T | 566_A | 1.535 | 0.99 |
| 37_A | 107_E | 1.533 | 0.99 |
| 80_L | 305_L | 1.525 | 0.99 |
| 796_G | 831_A | 1.525 | 0.99 |
| 34_A | 107_E | 1.522 | 0.99 |
| 60_D | 117_S | 1.517 | 0.99 |
| 266_I | 312_L | 1.516 | 0.99 |
| 204_E | 207_D | 1.505 | 0.99 |
| 751_Q | 803_Q | 1.497 | 0.99 |
| 769_K | 810_N | 1.489 | 0.99 |
| 769_K | 806_Y | 1.484 | 0.99 |
| 720_A | 767_S | 1.482 | 0.99 |
| 750_Q | 764_A | 1.453 | 0.98 |
| 9_Q | 13_M | 1.452 | 0.98 |
| 29_E | 44_L | 1.448 | 0.98 |
| 686_V | 732_L | 1.446 | 0.98 |
| 71_V | 96_A | 1.445 | 0.98 |
| 202_R | 206_L | 1.444 | 0.98 |
| 362_E | 365_F | 1.443 | 0.98 |
| 788_F | 827_A | 1.443 | 0.98 |
| 726_A | 779_L | 1.435 | 0.98 |
| 74_A | 100_V | 1.430 | 0.98 |
| 227_A | 253_A | 1.430 | 0.98 |
| 655_T | 786_D | 1.430 | 0.98 |
| 18_L | 28_I | 1.427 | 0.98 |
| 58_R | 121_Q | 1.427 | 0.98 |
| 751_Q | 805_G | 1.426 | 0.98 |
| 204_E | 208_R | 1.425 | 0.98 |
| 167_P | 186_K | 1.423 | 0.98 |
| 569_I | 636_F | 1.421 | 0.98 |
| 582_L | 812_F | 1.413 | 0.98 |
| 206_L | 210_A | 1.411 | 0.98 |
| 712_V | 715_A | 1.410 | 0.98 |
| 537_P | 763_A | 1.405 | 0.98 |
| 34_A | 38_H | 1.404 | 0.98 |
| 777_H | 781_G | 1.396 | 0.98 |
| 628_M | 635_L | 1.390 | 0.98 |
| 60_D | 121_Q | 1.390 | 0.98 |
| 790_L | 827_A | 1.384 | 0.98 |
| 777_H | 823_L | 1.380 | 0.97 |
| 702_V | 706_T | 1.376 | 0.97 |
| 299_E | 304_R | 1.371 | 0.97 |
| 794_A | 798_W | 1.368 | 0.97 |
| 138_E | 141_A | 1.367 | 0.97 |
| 225_V | 246_Q | 1.366 | 0.97 |
| 450_L | 454_G | 1.366 | 0.97 |
| 166_E | 169_A | 1.362 | 0.97 |
| 469_G | 472_I | 1.358 | 0.97 |
| 666_T | 695_A | 1.358 | 0.97 |
| 59_V | 191_Y | 1.357 | 0.97 |
| 202_R | 241_V | 1.356 | 0.97 |
| 352_T | 355_A | 1.355 | 0.97 |
| 628_M | 637_V | 1.355 | 0.97 |
| 222_Y | 253_A | 1.348 | 0.97 |
| 774_R | 819_H | 1.346 | 0.97 |
| 541_A | 763_A | 1.342 | 0.97 |
| 221_L | 235_L | 1.340 | 0.97 |
| 27_Q | 75_A | 1.338 | 0.97 |
| 364_R | 367_E | 1.336 | 0.97 |
| 451_S | 454_G | 1.334 | 0.97 |
| 403_R | 406_Q | 1.330 | 0.97 |
| 666_T | 714_V | 1.329 | 0.97 |
| 292_V | 312_L | 1.326 | 0.97 |
| 171_D | 175_R | 1.322 | 0.96 |
| 715_A | 728_L | 1.321 | 0.96 |
| 254_T | 278_L | 1.321 | 0.96 |
| 342_R | 346_D | 1.320 | 0.96 |
| 586_L | 804_G | 1.317 | 0.96 |
| 88_V | 257_L | 1.312 | 0.96 |
| 174_L | 186_K | 1.308 | 0.96 |
| 742_V | 780_L | 1.307 | 0.96 |
| 177_L | 182_V | 1.306 | 0.96 |
| 275_T | 291_V | 1.305 | 0.96 |
| 95_I | 212_I | 1.305 | 0.96 |
| 663_T | 744_H | 1.302 | 0.96 |
| 103_A | 217_S | 1.300 | 0.96 |
| 265_F | 278_L | 1.299 | 0.96 |
| 155_I | 161_T | 1.297 | 0.96 |
| 18_L | 48_R | 1.295 | 0.96 |
| 547_V | 590_V | 1.291 | 0.96 |
| 671_A | 701_L | 1.290 | 0.96 |
| 768_G | 772_G | 1.290 | 0.96 |
| 543_T | 561_L | 1.289 | 0.96 |
| 14_A | 69_V | 1.287 | 0.96 |
| 436_W | 446_A | 1.287 | 0.96 |
| 111_T | 211_P | 1.286 | 0.96 |
| 662_V | 674_A | 1.286 | 0.96 |
| 16_A | 20_T | 1.285 | 0.96 |
| 28_I | 44_L | 1.277 | 0.95 |
| 402_W | 406_Q | 1.276 | 0.95 |
| 206_L | 241_V | 1.275 | 0.95 |
| 80_L | 309_L | 1.273 | 0.95 |
| 422_R | 425_A | 1.270 | 0.95 |
| 393_A | 396_L | 1.268 | 0.95 |
| 749_T | 805_G | 1.267 | 0.95 |
| 223_S | 226_T | 1.266 | 0.95 |
| 139_I | 163_V | 1.265 | 0.95 |
| 32_A | 36_S | 1.263 | 0.95 |
| 751_Q | 798_W | 1.260 | 0.95 |
| 703_A | 706_T | 1.258 | 0.95 |
| 362_E | 366_W | 1.257 | 0.95 |
| 773_A | 813_L | 1.257 | 0.95 |
| 282_A | 289_A | 1.257 | 0.95 |
| 733_D | 739_L | 1.256 | 0.95 |
| 661_L | 739_L | 1.256 | 0.95 |
| 139_I | 143_I | 1.255 | 0.95 |
| 417_Y | 421_W | 1.254 | 0.95 |
| 688_T | 725_L | 1.253 | 0.95 |
| 678_A | 683_E | 1.250 | 0.95 |
| 15_Q | 19_D | 1.248 | 0.95 |
| 82_V | 319_L | 1.240 | 0.94 |
| 440_Y | 443_L | 1.235 | 0.94 |
| 619_A | 628_M | 1.235 | 0.94 |
| 719_T | 775_H | 1.234 | 0.94 |
| 790_L | 813_L | 1.231 | 0.94 |
| 367_E | 370_E | 1.227 | 0.94 |
| 132_A | 163_V | 1.227 | 0.94 |
| 454_G | 457_A | 1.223 | 0.94 |
| 264_F | 315_Q | 1.222 | 0.94 |
| 780_L | 785_L | 1.220 | 0.94 |
| 684_R | 737_P | 1.219 | 0.94 |
| 38_H | 110_A | 1.218 | 0.94 |
| 243_N | 253_A | 1.216 | 0.94 |
| 27_Q | 99_C | 1.213 | 0.94 |
| 686_V | 715_A | 1.212 | 0.94 |
| 751_Q | 802_H | 1.212 | 0.94 |
| 405_Q | 408_E | 1.211 | 0.93 |
| 439_F | 444_D | 1.210 | 0.93 |
| 418_R | 421_W | 1.208 | 0.93 |
| 477_H | 494_A | 1.206 | 0.93 |
| 294_S | 308_S | 1.204 | 0.93 |
| 688_T | 719_T | 1.203 | 0.93 |
| 758_R | 761_E | 1.201 | 0.93 |
| 477_H | 489_P | 1.199 | 0.93 |
| 87_V | 221_L | 1.198 | 0.93 |
| 137_A | 140_E | 1.197 | 0.93 |
| 130_A | 163_V | 1.196 | 0.93 |
| 481_A | 489_P | 1.190 | 0.93 |
| 590_V | 754_L | 1.190 | 0.93 |
| 251_A | 281_T | 1.189 | 0.93 |
| 657_R | 683_E | 1.187 | 0.93 |
| 149_R | 172_A | 1.184 | 0.92 |
| 256_R | 260_D | 1.180 | 0.92 |
| 666_T | 689_S | 1.176 | 0.92 |
| 791_F | 832_W | 1.175 | 0.92 |
| 678_A | 685_L | 1.173 | 0.92 |
| 690_R | 769_K | 1.173 | 0.92 |
| 422_R | 426_S | 1.173 | 0.92 |
| 138_E | 180_A | 1.173 | 0.92 |
| 659_S | 686_V | 1.172 | 0.92 |
| 569_I | 629_A | 1.168 | 0.92 |
| 1_F | 266_I | 1.168 | 0.92 |
| 34_A | 37_A | 1.164 | 0.92 |
| 697_G | 700_E | 1.159 | 0.91 |
| 402_W | 405_Q | 1.158 | 0.91 |
| 80_L | 323_K | 1.158 | 0.91 |
| 44_L | 48_R | 1.156 | 0.91 |
| 720_A | 775_H | 1.156 | 0.91 |
| 745_A | 791_F | 1.154 | 0.91 |
| 306_L | 324_V | 1.154 | 0.91 |
| 547_V | 587_G | 1.152 | 0.91 |
| 785_L | 788_F | 1.151 | 0.91 |
| 559_L | 563_T | 1.150 | 0.91 |
| 403_R | 415_W | 1.145 | 0.91 |
| 66_L | 270_P | 1.144 | 0.91 |
| 693_Q | 715_A | 1.144 | 0.91 |
| 757_T | 804_G | 1.142 | 0.91 |
| 364_R | 369_V | 1.140 | 0.90 |
| 146_W | 149_R | 1.137 | 0.90 |
| 698_V | 714_V | 1.136 | 0.90 |
| 666_T | 671_A | 1.135 | 0.90 |
| 689_S | 692_G | 1.133 | 0.90 |
| 666_T | 670_G | 1.132 | 0.90 |
| 71_V | 99_C | 1.130 | 0.90 |
| 309_L | 319_L | 1.129 | 0.90 |
| 6_Q | 63_Q | 1.127 | 0.90 |
| 798_W | 805_G | 1.126 | 0.90 |
| 382_R | 387_E | 1.126 | 0.90 |
| 417_Y | 422_R | 1.124 | 0.90 |
| 813_L | 817_A | 1.124 | 0.90 |
| 174_L | 178_D | 1.123 | 0.90 |
| 3_F | 100_V | 1.122 | 0.90 |
| 60_D | 65_A | 1.122 | 0.90 |
| 151_A | 195_C | 1.120 | 0.89 |
| 404_R | 407_S | 1.115 | 0.89 |
| 588_R | 627_Q | 1.113 | 0.89 |
| 421_W | 425_A | 1.111 | 0.89 |
| 402_W | 415_W | 1.111 | 0.89 |
| 80_L | 324_V | 1.110 | 0.89 |
| 21_S | 80_L | 1.110 | 0.89 |
| 436_W | 439_F | 1.107 | 0.89 |
| 133_E | 182_V | 1.107 | 0.89 |
| 761_E | 764_A | 1.105 | 0.89 |
| 19_D | 48_R | 1.105 | 0.89 |
| 669_L | 791_F | 1.102 | 0.88 |
| 390_A | 394_A | 1.101 | 0.88 |
| 77_W | 305_L | 1.101 | 0.88 |
| 667_G | 690_R | 1.100 | 0.88 |
| 625_D | 637_V | 1.100 | 0.88 |
| 436_W | 443_L | 1.100 | 0.88 |
| 436_W | 444_D | 1.099 | 0.88 |
| 4_P | 70_M | 1.098 | 0.88 |
| 665_G | 671_A | 1.095 | 0.88 |
| 798_W | 801_G | 1.095 | 0.88 |
| 577_R | 580_Q | 1.095 | 0.88 |
| 16_A | 301_D | 1.092 | 0.88 |
| 723_P | 726_A | 1.092 | 0.88 |
| 728_L | 731_R | 1.090 | 0.88 |
| 832_W | 835_W | 1.090 | 0.88 |
| 561_L | 587_G | 1.090 | 0.88 |
| 821_R | 827_A | 1.088 | 0.88 |
| 222_Y | 256_R | 1.088 | 0.88 |
| 726_A | 730_Q | 1.087 | 0.87 |
| 71_V | 100_V | 1.087 | 0.87 |
| 92_Q | 193_S | 1.084 | 0.87 |
| 450_L | 453_A | 1.078 | 0.87 |
| 767_S | 771_D | 1.078 | 0.87 |
| 473_A | 477_H | 1.077 | 0.87 |
| 303_R | 307_L | 1.075 | 0.87 |
| 391_S | 417_Y | 1.071 | 0.86 |
| 668_A | 671_A | 1.071 | 0.86 |
| 770_I | 812_F | 1.070 | 0.86 |
| 320_D | 323_K | 1.070 | 0.86 |
| 582_L | 811_A | 1.069 | 0.86 |
| 405_Q | 415_W | 1.069 | 0.86 |
| 770_I | 773_A | 1.069 | 0.86 |
| 733_D | 783_R | 1.067 | 0.86 |
| 717_C | 725_L | 1.066 | 0.86 |
| 30_A | 75_A | 1.064 | 0.86 |
| 62_V | 92_Q | 1.064 | 0.86 |
| 616_L | 620_L | 1.064 | 0.86 |
| 23_V | 79_A | 1.062 | 0.86 |
| 142_R | 176_E | 1.062 | 0.86 |
| 390_A | 393_A | 1.061 | 0.86 |
| 1_F | 268_V | 1.060 | 0.86 |
| 588_R | 593_E | 1.060 | 0.86 |
| 423_P | 426_S | 1.058 | 0.86 |
| 753_P | 756_E | 1.058 | 0.86 |
| 365_F | 370_E | 1.057 | 0.85 |
| 31_C | 106_L | 1.056 | 0.85 |
| 717_C | 724_A | 1.056 | 0.85 |
| 451_S | 455_R | 1.053 | 0.85 |
| 454_G | 461_D | 1.049 | 0.85 |
| 139_I | 161_T | 1.048 | 0.85 |
| 189_V | 193_S | 1.046 | 0.85 |
| 591_A | 598_W | 1.045 | 0.85 |
| 477_H | 482_E | 1.042 | 0.84 |
| 403_R | 407_S | 1.042 | 0.84 |
| 727_A | 731_R | 1.041 | 0.84 |
| 311_E | 314_T | 1.036 | 0.84 |
| 753_P | 761_E | 1.036 | 0.84 |
| 657_R | 786_D | 1.035 | 0.84 |
| 592_L | 801_G | 1.035 | 0.84 |
| 133_E | 159_R | 1.035 | 0.84 |
| 135_P | 139_I | 1.034 | 0.84 |
| 567_V | 584_W | 1.033 | 0.84 |
| 400_S | 403_R | 1.033 | 0.84 |
| 667_G | 747_G | 1.032 | 0.84 |
| 585_G | 593_E | 1.030 | 0.83 |
| 690_R | 806_Y | 1.030 | 0.83 |
| 254_T | 265_F | 1.030 | 0.83 |
| 275_T | 293_G | 1.029 | 0.83 |
| 402_W | 417_Y | 1.028 | 0.83 |
| 668_A | 834_A | 1.026 | 0.83 |
| 545_A | 548_Q | 1.026 | 0.83 |
| 202_R | 245_R | 1.025 | 0.83 |
| 762_L | 805_G | 1.021 | 0.83 |
| 560_W | 600_G | 1.021 | 0.83 |
| 171_D | 174_L | 1.021 | 0.83 |
| 366_W | 370_E | 1.020 | 0.83 |
| 436_W | 441_R | 1.020 | 0.83 |
| 688_T | 715_A | 1.019 | 0.82 |
| 203_E | 206_L | 1.018 | 0.82 |
| 726_A | 775_H | 1.018 | 0.82 |
| 589_V | 592_L | 1.018 | 0.82 |
| 59_V | 62_V | 1.016 | 0.82 |
| 662_V | 665_G | 1.016 | 0.82 |
| 587_G | 601_L | 1.010 | 0.82 |
| 6_Q | 189_V | 1.009 | 0.82 |
| 660_V | 787_A | 1.009 | 0.82 |
| 99_C | 104_L | 1.007 | 0.81 |
| 689_S | 695_A | 1.007 | 0.81 |
| 454_G | 458_A | 1.006 | 0.81 |
| 747_G | 803_Q | 1.006 | 0.81 |
| 587_G | 598_W | 1.006 | 0.81 |
| 795_A | 803_Q | 1.005 | 0.81 |
| 816_L | 819_H | 1.005 | 0.81 |
| 447_P | 451_S | 1.004 | 0.81 |
| 743_F | 787_A | 1.003 | 0.81 |
Prob = P(contact | scaled_score, seq/len).
Scaled Score = (raw_score/average(raw_scores)).
- Text file of contact predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
- Import to GREMLIN BETA - features includes ability to upload PDB and latest P(contact) calculation based on eLife 2015 fitting to PDB data.
GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled Score > 1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-position alignment confidence. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | M | Cov | P(%) | HHΔ | |
| 2vz8A | 2 | 0.9486 | 100 | 0.386 | Contact Map |
| 2qo3A | 2 | 0.4134 | 100 | 0.492 | Contact Map |
| 4mz0A | 2 | 0.3978 | 100 | 0.494 | Contact Map |
| 2hg4A | 6 | 0.411 | 100 | 0.496 | Contact Map |
| 3zenD | 3 | 0.681 | 100 | 0.51 | Contact Map |
| 3tzyA | 2 | 0.399 | 100 | 0.535 | Contact Map |
| 4qbuA | 1 | 0.3931 | 100 | 0.544 | Contact Map |
| 3hhdA | 4 | 0.411 | 100 | 0.549 | Contact Map |
| 4rl1A | 1 | 0.3716 | 100 | 0.558 | Contact Map |
| 3g87A | 1 | 0.3309 | 100 | 0.566 | Contact Map |
Cov = coverage of hit
P(%) = probability
Sequence Conservation (Image Generated using WebLogo v3)