| C-A |
| ID: | 1504645611 |
Query Sequence |
Download Alignment We filter this alignment to remove positions that have > 75% gaps before running GREMLIN. |
| Length: | 889 (887) | ||
| Sequences: | 13859 (11760) | ||
| Seq/Len: | 15.625 | ||
| Nf(neff/√len): | 394.9 |
HHblits Results: (2016_02)
Sequences per length for each position, BEFORE the coverage/gap filter was applied
Legend: Dots above the red line, indicates positions where there is > 5 sequences per length (if visible, green bar = 20 seq/len). Point of this graphic is to give you an idea if resubmitting a sub-portion of your sequence might help increase the overall Seq/Len (which after applying the coverage filter is at: 15.625).
Sequences per length for each position, AFTER the coverage/gap filter was applied
Residue pairs sorted by coevolution strength:
Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] covarying residues with sequence seperation > 3. The i and j are positions as given in the input sequence.
| i | j | Scaled score | Prob |
| 597_P | 614_V | 4.679 | 1.00 |
| 799_L | 838_G | 3.746 | 1.00 |
| 509_R | 535_V | 3.725 | 1.00 |
| 507_Q | 596_L | 3.414 | 1.00 |
| 264_A | 295_A | 3.398 | 1.00 |
| 616_S | 808_E | 3.191 | 1.00 |
| 507_Q | 808_E | 3.094 | 1.00 |
| 537_F | 546_R | 3.090 | 1.00 |
| 552_Q | 602_Y | 2.996 | 1.00 |
| 302_R | 310_T | 2.794 | 1.00 |
| 839_R | 847_E | 2.687 | 1.00 |
| 784_L | 800_Y | 2.662 | 1.00 |
| 638_R | 663_A | 2.642 | 1.00 |
| 489_V | 529_L | 2.641 | 1.00 |
| 493_F | 529_L | 2.587 | 1.00 |
| 741_Q | 759_I | 2.516 | 1.00 |
| 498_K | 502_L | 2.514 | 1.00 |
| 796_T | 849_L | 2.513 | 1.00 |
| 61_T | 71_L | 2.471 | 1.00 |
| 783_V | 838_G | 2.464 | 1.00 |
| 464_V | 489_V | 2.448 | 1.00 |
| 511_A | 555_V | 2.425 | 1.00 |
| 756_N | 781_F | 2.413 | 1.00 |
| 466_Q | 470_N | 2.382 | 1.00 |
| 237_A | 247_A | 2.372 | 1.00 |
| 255_V | 417_L | 2.337 | 1.00 |
| 486_E | 490_K | 2.335 | 1.00 |
| 504_C | 532_A | 2.329 | 1.00 |
| 813_D | 816_L | 2.321 | 1.00 |
| 495_V | 522_T | 2.298 | 1.00 |
| 616_S | 619_A | 2.297 | 1.00 |
| 508_D | 556_R | 2.295 | 1.00 |
| 208_R | 403_P | 2.285 | 1.00 |
| 194_R | 314_Q | 2.283 | 1.00 |
| 259_W | 413_A | 2.274 | 1.00 |
| 802_T | 831_L | 2.267 | 1.00 |
| 304_F | 421_L | 2.263 | 1.00 |
| 619_A | 752_S | 2.247 | 1.00 |
| 680_E | 684_E | 2.245 | 1.00 |
| 466_Q | 469_A | 2.212 | 1.00 |
| 49_N | 53_A | 2.195 | 1.00 |
| 506_A | 596_L | 2.174 | 1.00 |
| 240_R | 305_Q | 2.138 | 1.00 |
| 404_D | 408_D | 2.132 | 1.00 |
| 493_F | 497_N | 2.126 | 1.00 |
| 504_C | 508_D | 2.118 | 1.00 |
| 858_I | 885_L | 2.108 | 1.00 |
| 781_F | 801_I | 2.104 | 1.00 |
| 187_D | 321_H | 2.104 | 1.00 |
| 489_V | 587_P | 2.084 | 1.00 |
| 51_L | 153_L | 2.083 | 1.00 |
| 253_A | 296_V | 2.063 | 1.00 |
| 395_W | 407_I | 2.053 | 1.00 |
| 508_D | 532_A | 2.042 | 1.00 |
| 548_A | 609_Q | 2.032 | 1.00 |
| 457_Y | 465_K | 2.031 | 1.00 |
| 783_V | 846_I | 2.029 | 1.00 |
| 376_P | 379_F | 2.022 | 1.00 |
| 509_R | 600_I | 1.991 | 1.00 |
| 342_A | 345_P | 1.987 | 1.00 |
| 495_V | 526_G | 1.986 | 1.00 |
| 841_T | 847_E | 1.970 | 1.00 |
| 474_P | 482_H | 1.968 | 1.00 |
| 54_R | 149_E | 1.967 | 1.00 |
| 520_Q | 645_L | 1.946 | 1.00 |
| 668_N | 671_R | 1.937 | 1.00 |
| 470_N | 473_R | 1.932 | 1.00 |
| 133_M | 138_A | 1.927 | 1.00 |
| 45_Q | 49_N | 1.926 | 1.00 |
| 600_I | 811_A | 1.921 | 1.00 |
| 780_G | 824_H | 1.906 | 1.00 |
| 637_D | 688_T | 1.899 | 1.00 |
| 780_G | 802_T | 1.873 | 1.00 |
| 264_A | 297_D | 1.861 | 1.00 |
| 695_A | 723_D | 1.853 | 1.00 |
| 597_P | 808_E | 1.838 | 1.00 |
| 115_L | 137_I | 1.828 | 1.00 |
| 856_V | 865_L | 1.819 | 1.00 |
| 33_E | 126_N | 1.817 | 1.00 |
| 492_A | 529_L | 1.815 | 1.00 |
| 841_T | 845_E | 1.813 | 1.00 |
| 266_C | 293_L | 1.813 | 1.00 |
| 326_G | 330_M | 1.809 | 1.00 |
| 436_L | 440_Q | 1.804 | 1.00 |
| 395_W | 411_F | 1.801 | 1.00 |
| 824_H | 829_E | 1.793 | 1.00 |
| 622_N | 778_N | 1.792 | 1.00 |
| 798_E | 833_R | 1.789 | 1.00 |
| 51_L | 150_F | 1.779 | 1.00 |
| 550_L | 555_V | 1.771 | 1.00 |
| 489_V | 493_F | 1.766 | 1.00 |
| 223_I | 393_V | 1.765 | 1.00 |
| 796_T | 837_L | 1.759 | 1.00 |
| 33_E | 36_Y | 1.753 | 1.00 |
| 61_T | 113_W | 1.750 | 1.00 |
| 785_D | 789_R | 1.750 | 1.00 |
| 509_R | 533_V | 1.737 | 1.00 |
| 512_I | 523_A | 1.734 | 1.00 |
| 595_D | 616_S | 1.724 | 1.00 |
| 483_M | 522_T | 1.724 | 1.00 |
| 477_F | 663_A | 1.723 | 1.00 |
| 595_D | 618_R | 1.723 | 1.00 |
| 691_N | 754_W | 1.721 | 1.00 |
| 233_F | 244_P | 1.711 | 1.00 |
| 505_K | 508_D | 1.708 | 1.00 |
| 665_V | 687_I | 1.705 | 1.00 |
| 458_C | 461_E | 1.694 | 1.00 |
| 629_R | 777_A | 1.689 | 1.00 |
| 869_E | 883_V | 1.688 | 1.00 |
| 638_R | 687_I | 1.679 | 1.00 |
| 148_A | 283_D | 1.675 | 1.00 |
| 873_L | 880_A | 1.665 | 1.00 |
| 491_R | 519_H | 1.658 | 1.00 |
| 472_D | 486_E | 1.655 | 1.00 |
| 619_A | 806_L | 1.647 | 1.00 |
| 303_S | 306_E | 1.643 | 1.00 |
| 68_Q | 72_E | 1.639 | 1.00 |
| 478_D | 518_A | 1.638 | 1.00 |
| 758_H | 845_E | 1.631 | 1.00 |
| 593_N | 596_L | 1.624 | 1.00 |
| 305_Q | 426_Q | 1.622 | 1.00 |
| 671_R | 677_H | 1.611 | 1.00 |
| 637_D | 716_R | 1.608 | 1.00 |
| 146_L | 285_V | 1.606 | 1.00 |
| 477_F | 685_H | 1.588 | 1.00 |
| 378_V | 381_D | 1.588 | 1.00 |
| 745_L | 754_W | 1.587 | 1.00 |
| 758_H | 771_P | 1.586 | 1.00 |
| 674_D | 677_H | 1.585 | 1.00 |
| 637_D | 662_G | 1.584 | 1.00 |
| 326_G | 329_V | 1.578 | 1.00 |
| 781_F | 799_L | 1.578 | 1.00 |
| 44_T | 150_F | 1.577 | 1.00 |
| 474_P | 663_A | 1.567 | 1.00 |
| 432_D | 436_L | 1.566 | 1.00 |
| 649_L | 691_N | 1.565 | 1.00 |
| 188_K | 324_F | 1.562 | 1.00 |
| 526_G | 530_A | 1.562 | 1.00 |
| 48_W | 118_I | 1.558 | 1.00 |
| 50_L | 53_A | 1.552 | 1.00 |
| 465_K | 469_A | 1.550 | 1.00 |
| 55_H | 149_E | 1.543 | 1.00 |
| 464_V | 529_L | 1.543 | 1.00 |
| 253_A | 267_L | 1.537 | 1.00 |
| 652_Y | 754_W | 1.535 | 1.00 |
| 221_R | 408_D | 1.534 | 1.00 |
| 667_P | 681_L | 1.533 | 1.00 |
| 643_A | 649_L | 1.533 | 1.00 |
| 95_R | 98_D | 1.532 | 1.00 |
| 250_T | 307_R | 1.528 | 1.00 |
| 543_E | 547_Q | 1.526 | 1.00 |
| 548_A | 602_Y | 1.525 | 1.00 |
| 459_L | 620_A | 1.524 | 1.00 |
| 489_V | 492_A | 1.519 | 1.00 |
| 523_A | 559_L | 1.518 | 1.00 |
| 35_D | 126_N | 1.518 | 1.00 |
| 251_A | 418_L | 1.517 | 1.00 |
| 547_Q | 551_E | 1.503 | 1.00 |
| 638_R | 665_V | 1.500 | 1.00 |
| 873_L | 881_A | 1.498 | 1.00 |
| 541_Q | 549_M | 1.498 | 1.00 |
| 246_T | 312_Q | 1.498 | 1.00 |
| 512_I | 524_V | 1.493 | 1.00 |
| 497_N | 588_I | 1.493 | 1.00 |
| 561_T | 564_I | 1.493 | 1.00 |
| 329_V | 333_M | 1.491 | 1.00 |
| 109_D | 112_R | 1.491 | 1.00 |
| 681_L | 685_H | 1.489 | 1.00 |
| 519_H | 561_T | 1.482 | 1.00 |
| 198_L | 266_C | 1.478 | 1.00 |
| 219_Q | 399_E | 1.477 | 1.00 |
| 665_V | 681_L | 1.477 | 1.00 |
| 653_D | 691_N | 1.473 | 1.00 |
| 504_C | 510_V | 1.470 | 1.00 |
| 822_L | 831_L | 1.466 | 1.00 |
| 462_Q | 621_A | 1.465 | 1.00 |
| 788_M | 800_Y | 1.457 | 1.00 |
| 719_L | 745_L | 1.456 | 1.00 |
| 235_Q | 239_K | 1.452 | 1.00 |
| 623_T | 754_W | 1.452 | 1.00 |
| 781_F | 838_G | 1.449 | 1.00 |
| 691_N | 694_P | 1.445 | 1.00 |
| 377_Q | 380_I | 1.443 | 1.00 |
| 483_M | 518_A | 1.438 | 1.00 |
| 168_F | 171_Y | 1.433 | 1.00 |
| 259_W | 410_M | 1.432 | 1.00 |
| 189_E | 193_Q | 1.432 | 1.00 |
| 628_N | 660_V | 1.430 | 1.00 |
| 188_K | 192_Q | 1.425 | 1.00 |
| 313_K | 317_E | 1.425 | 1.00 |
| 257_E | 298_L | 1.425 | 1.00 |
| 299_D | 302_R | 1.424 | 1.00 |
| 521_V | 654_I | 1.415 | 1.00 |
| 478_D | 481_G | 1.412 | 1.00 |
| 669_A | 672_Q | 1.411 | 1.00 |
| 328_E | 331_R | 1.406 | 0.99 |
| 535_V | 553_A | 1.403 | 0.99 |
| 190_Y | 318_D | 1.401 | 0.99 |
| 514_M | 523_A | 1.400 | 0.99 |
| 40_D | 43_R | 1.399 | 0.99 |
| 474_P | 477_F | 1.399 | 0.99 |
| 652_Y | 691_N | 1.398 | 0.99 |
| 346_V | 349_T | 1.396 | 0.99 |
| 297_D | 302_R | 1.396 | 0.99 |
| 415_A | 419_H | 1.394 | 0.99 |
| 691_N | 745_L | 1.394 | 0.99 |
| 215_D | 218_F | 1.388 | 0.99 |
| 28_C | 31_Y | 1.387 | 0.99 |
| 460_H | 617_H | 1.387 | 0.99 |
| 592_A | 596_L | 1.378 | 0.99 |
| 68_Q | 71_L | 1.378 | 0.99 |
| 523_A | 527_A | 1.373 | 0.99 |
| 552_Q | 609_Q | 1.373 | 0.99 |
| 613_V | 807_A | 1.372 | 0.99 |
| 642_L | 693_V | 1.367 | 0.99 |
| 552_Q | 813_D | 1.366 | 0.99 |
| 229_A | 419_H | 1.364 | 0.99 |
| 296_V | 311_I | 1.364 | 0.99 |
| 816_L | 820_R | 1.361 | 0.99 |
| 254_A | 307_R | 1.358 | 0.99 |
| 463_I | 467_A | 1.358 | 0.99 |
| 384_A | 393_V | 1.358 | 0.99 |
| 871_A | 874_K | 1.351 | 0.99 |
| 464_V | 492_A | 1.349 | 0.99 |
| 408_D | 412_D | 1.348 | 0.99 |
| 434_I | 440_Q | 1.348 | 0.99 |
| 463_I | 525_L | 1.347 | 0.99 |
| 185_V | 189_E | 1.346 | 0.99 |
| 560_T | 564_I | 1.343 | 0.99 |
| 615_I | 807_A | 1.342 | 0.99 |
| 39_L | 127_T | 1.338 | 0.99 |
| 623_T | 652_Y | 1.336 | 0.99 |
| 457_Y | 461_E | 1.334 | 0.99 |
| 171_Y | 174_A | 1.333 | 0.99 |
| 219_Q | 404_D | 1.330 | 0.99 |
| 541_Q | 646_S | 1.330 | 0.99 |
| 424_T | 427_V | 1.329 | 0.99 |
| 814_P | 818_Q | 1.327 | 0.99 |
| 250_T | 311_I | 1.327 | 0.99 |
| 207_T | 406_M | 1.325 | 0.99 |
| 551_E | 609_Q | 1.324 | 0.99 |
| 755_S | 801_I | 1.323 | 0.99 |
| 409_D | 413_A | 1.320 | 0.99 |
| 62_I | 137_I | 1.317 | 0.99 |
| 26_V | 29_H | 1.316 | 0.99 |
| 624_I | 659_S | 1.314 | 0.99 |
| 252_Y | 346_V | 1.314 | 0.99 |
| 187_D | 323_L | 1.305 | 0.99 |
| 721_S | 754_W | 1.304 | 0.99 |
| 776_L | 779_Q | 1.295 | 0.99 |
| 640_L | 667_P | 1.292 | 0.99 |
| 276_P | 280_Q | 1.289 | 0.99 |
| 460_H | 592_A | 1.289 | 0.99 |
| 476_V | 518_A | 1.286 | 0.99 |
| 444_R | 447_V | 1.282 | 0.99 |
| 345_P | 349_T | 1.282 | 0.99 |
| 226_D | 229_A | 1.279 | 0.99 |
| 41_H | 120_V | 1.273 | 0.99 |
| 350_S | 354_L | 1.268 | 0.99 |
| 188_K | 332_E | 1.265 | 0.99 |
| 865_L | 883_V | 1.262 | 0.99 |
| 251_A | 421_L | 1.262 | 0.99 |
| 641_G | 666_Y | 1.260 | 0.99 |
| 691_N | 721_S | 1.259 | 0.99 |
| 327_V | 330_M | 1.257 | 0.99 |
| 837_L | 852_E | 1.257 | 0.99 |
| 50_L | 153_L | 1.256 | 0.99 |
| 751_A | 801_I | 1.255 | 0.99 |
| 479_S | 668_N | 1.254 | 0.99 |
| 397_V | 407_I | 1.253 | 0.99 |
| 56_D | 167_T | 1.252 | 0.99 |
| 824_H | 831_L | 1.249 | 0.99 |
| 800_Y | 833_R | 1.243 | 0.98 |
| 244_P | 391_L | 1.241 | 0.98 |
| 298_L | 302_R | 1.241 | 0.98 |
| 69_R | 72_E | 1.236 | 0.98 |
| 807_A | 821_F | 1.236 | 0.98 |
| 44_T | 129_L | 1.234 | 0.98 |
| 50_L | 157_S | 1.227 | 0.98 |
| 717_L | 743_V | 1.226 | 0.98 |
| 474_P | 484_T | 1.224 | 0.98 |
| 349_T | 352_I | 1.224 | 0.98 |
| 533_V | 597_P | 1.223 | 0.98 |
| 634_N | 637_D | 1.222 | 0.98 |
| 649_L | 754_W | 1.222 | 0.98 |
| 31_Y | 36_Y | 1.222 | 0.98 |
| 293_L | 329_V | 1.220 | 0.98 |
| 232_T | 419_H | 1.219 | 0.98 |
| 255_V | 414_F | 1.218 | 0.98 |
| 640_L | 682_M | 1.217 | 0.98 |
| 782_R | 824_H | 1.217 | 0.98 |
| 325_S | 329_V | 1.216 | 0.98 |
| 507_Q | 597_P | 1.212 | 0.98 |
| 433_V | 437_P | 1.212 | 0.98 |
| 234_K | 386_D | 1.210 | 0.98 |
| 793_V | 840_Y | 1.207 | 0.98 |
| 623_T | 753_I | 1.206 | 0.98 |
| 437_P | 440_Q | 1.206 | 0.98 |
| 82_T | 119_G | 1.206 | 0.98 |
| 515_D | 561_T | 1.203 | 0.98 |
| 477_F | 482_H | 1.201 | 0.98 |
| 85_S | 122_K | 1.200 | 0.98 |
| 476_V | 521_V | 1.197 | 0.98 |
| 648_D | 748_A | 1.196 | 0.98 |
| 484_T | 487_E | 1.195 | 0.98 |
| 379_F | 382_C | 1.194 | 0.98 |
| 223_I | 411_F | 1.194 | 0.98 |
| 838_G | 848_F | 1.193 | 0.98 |
| 553_A | 602_Y | 1.189 | 0.98 |
| 192_Q | 332_E | 1.189 | 0.98 |
| 433_V | 440_Q | 1.188 | 0.98 |
| 193_Q | 196_D | 1.188 | 0.98 |
| 726_P | 729_L | 1.187 | 0.98 |
| 324_F | 332_E | 1.187 | 0.98 |
| 649_L | 721_S | 1.186 | 0.98 |
| 240_R | 309_R | 1.182 | 0.98 |
| 98_D | 102_K | 1.181 | 0.98 |
| 194_R | 317_E | 1.180 | 0.98 |
| 403_P | 406_M | 1.179 | 0.98 |
| 774_L | 845_E | 1.177 | 0.98 |
| 28_C | 36_Y | 1.177 | 0.98 |
| 657_P | 662_G | 1.176 | 0.98 |
| 785_D | 791_C | 1.174 | 0.98 |
| 463_I | 489_V | 1.174 | 0.98 |
| 249_M | 267_L | 1.174 | 0.98 |
| 402_F | 407_I | 1.169 | 0.97 |
| 236_R | 422_A | 1.169 | 0.97 |
| 99_I | 121_T | 1.166 | 0.97 |
| 254_A | 417_L | 1.163 | 0.97 |
| 343_L | 346_V | 1.158 | 0.97 |
| 190_Y | 194_R | 1.157 | 0.97 |
| 623_T | 752_S | 1.156 | 0.97 |
| 792_P | 795_V | 1.156 | 0.97 |
| 534_Y | 651_V | 1.155 | 0.97 |
| 481_G | 491_R | 1.145 | 0.97 |
| 652_Y | 745_L | 1.145 | 0.97 |
| 725_I | 744_S | 1.144 | 0.97 |
| 657_P | 664_L | 1.143 | 0.97 |
| 103_M | 132_S | 1.143 | 0.97 |
| 751_A | 755_S | 1.143 | 0.97 |
| 689_V | 717_L | 1.143 | 0.97 |
| 462_Q | 625_A | 1.141 | 0.97 |
| 623_T | 653_D | 1.138 | 0.97 |
| 643_A | 691_N | 1.138 | 0.97 |
| 447_V | 840_Y | 1.138 | 0.97 |
| 623_T | 721_S | 1.138 | 0.97 |
| 614_V | 811_A | 1.137 | 0.97 |
| 221_R | 404_D | 1.135 | 0.97 |
| 9_V | 12_A | 1.134 | 0.97 |
| 649_L | 652_Y | 1.134 | 0.97 |
| 103_M | 119_G | 1.126 | 0.97 |
| 257_E | 260_S | 1.123 | 0.97 |
| 743_V | 759_I | 1.121 | 0.97 |
| 633_V | 662_G | 1.119 | 0.96 |
| 548_A | 552_Q | 1.119 | 0.96 |
| 492_A | 526_G | 1.118 | 0.96 |
| 464_V | 493_F | 1.113 | 0.96 |
| 335_R | 338_G | 1.112 | 0.96 |
| 627_I | 652_Y | 1.110 | 0.96 |
| 783_V | 799_L | 1.110 | 0.96 |
| 866_G | 869_E | 1.110 | 0.96 |
| 440_Q | 443_E | 1.109 | 0.96 |
| 351_A | 354_L | 1.109 | 0.96 |
| 103_M | 106_R | 1.106 | 0.96 |
| 57_M | 60_A | 1.104 | 0.96 |
| 467_A | 489_V | 1.104 | 0.96 |
| 331_R | 334_A | 1.103 | 0.96 |
| 148_A | 152_M | 1.102 | 0.96 |
| 628_N | 656_G | 1.101 | 0.96 |
| 615_I | 752_S | 1.101 | 0.96 |
| 528_L | 598_A | 1.100 | 0.96 |
| 637_D | 689_V | 1.099 | 0.96 |
| 207_T | 210_H | 1.097 | 0.96 |
| 226_D | 419_H | 1.096 | 0.96 |
| 498_K | 501_E | 1.095 | 0.96 |
| 242_L | 246_T | 1.094 | 0.96 |
| 511_A | 550_L | 1.093 | 0.96 |
| 83_D | 122_K | 1.092 | 0.96 |
| 721_S | 752_S | 1.091 | 0.96 |
| 623_T | 691_N | 1.091 | 0.96 |
| 224_R | 392_Q | 1.090 | 0.96 |
| 502_L | 557_F | 1.090 | 0.96 |
| 653_D | 754_W | 1.089 | 0.96 |
| 62_I | 136_L | 1.085 | 0.96 |
| 329_V | 332_E | 1.084 | 0.96 |
| 692_S | 697_M | 1.081 | 0.95 |
| 618_R | 804_H | 1.080 | 0.95 |
| 439_W | 443_E | 1.080 | 0.95 |
| 651_V | 753_I | 1.080 | 0.95 |
| 376_P | 380_I | 1.078 | 0.95 |
| 782_R | 802_T | 1.077 | 0.95 |
| 434_I | 437_P | 1.077 | 0.95 |
| 854_N | 869_E | 1.076 | 0.95 |
| 800_Y | 822_L | 1.073 | 0.95 |
| 233_F | 247_A | 1.073 | 0.95 |
| 118_I | 129_L | 1.069 | 0.95 |
| 640_L | 681_L | 1.068 | 0.95 |
| 232_T | 423_R | 1.068 | 0.95 |
| 377_Q | 381_D | 1.066 | 0.95 |
| 215_D | 400_G | 1.065 | 0.95 |
| 858_I | 863_I | 1.063 | 0.95 |
| 40_D | 154_Y | 1.063 | 0.95 |
| 19_D | 22_G | 1.062 | 0.95 |
| 221_R | 411_F | 1.062 | 0.95 |
| 730_P | 733_M | 1.058 | 0.95 |
| 599_Y | 615_I | 1.058 | 0.95 |
| 691_N | 696_L | 1.055 | 0.95 |
| 435_T | 440_Q | 1.054 | 0.95 |
| 544_L | 609_Q | 1.052 | 0.95 |
| 442_A | 446_S | 1.052 | 0.95 |
| 242_L | 308_A | 1.050 | 0.94 |
| 224_R | 390_G | 1.046 | 0.94 |
| 776_L | 805_G | 1.046 | 0.94 |
| 620_A | 753_I | 1.045 | 0.94 |
| 236_R | 240_R | 1.043 | 0.94 |
| 653_D | 745_L | 1.043 | 0.94 |
| 720_L | 725_I | 1.042 | 0.94 |
| 524_V | 654_I | 1.041 | 0.94 |
| 727_L | 731_D | 1.041 | 0.94 |
| 433_V | 436_L | 1.038 | 0.94 |
| 39_L | 44_T | 1.036 | 0.94 |
| 783_V | 791_C | 1.034 | 0.94 |
| 268_N | 344_M | 1.033 | 0.94 |
| 491_R | 494_A | 1.033 | 0.94 |
| 504_C | 530_A | 1.032 | 0.94 |
| 432_D | 435_T | 1.032 | 0.94 |
| 43_R | 157_S | 1.031 | 0.94 |
| 544_L | 548_A | 1.030 | 0.94 |
| 23_Y | 28_C | 1.030 | 0.94 |
| 481_G | 518_A | 1.030 | 0.94 |
| 511_A | 537_F | 1.027 | 0.94 |
| 315_L | 319_L | 1.026 | 0.94 |
| 67_E | 71_L | 1.025 | 0.93 |
| 642_L | 692_S | 1.022 | 0.93 |
| 650_S | 654_I | 1.022 | 0.93 |
| 536_P | 749_T | 1.022 | 0.93 |
| 633_V | 637_D | 1.020 | 0.93 |
| 544_L | 547_Q | 1.019 | 0.93 |
| 376_P | 381_D | 1.018 | 0.93 |
| 306_E | 309_R | 1.017 | 0.93 |
| 639_V | 657_P | 1.016 | 0.93 |
| 249_M | 253_A | 1.016 | 0.93 |
| 623_T | 627_I | 1.016 | 0.93 |
| 13_Y | 287_D | 1.015 | 0.93 |
| 443_E | 447_V | 1.014 | 0.93 |
| 855_Q | 864_E | 1.013 | 0.93 |
| 432_D | 437_P | 1.011 | 0.93 |
| 780_G | 829_E | 1.010 | 0.93 |
| 110_T | 136_L | 1.010 | 0.93 |
| 751_A | 806_L | 1.010 | 0.93 |
| 624_I | 656_G | 1.010 | 0.93 |
| 328_E | 332_E | 1.009 | 0.93 |
| 470_N | 486_E | 1.009 | 0.93 |
| 717_L | 741_Q | 1.009 | 0.93 |
| 491_R | 522_T | 1.008 | 0.93 |
| 839_R | 849_L | 1.007 | 0.93 |
| 782_R | 831_L | 1.005 | 0.93 |
| 461_E | 464_V | 1.003 | 0.93 |
| 327_V | 331_R | 1.002 | 0.92 |
| 319_L | 322_R | 1.001 | 0.92 |
| 533_V | 600_I | 1.000 | 0.92 |
| 686_G | 714_A | 1.000 | 0.92 |
Prob = P(contact | scaled_score, seq/len).
Scaled Score = (raw_score/average(raw_scores)).
- Text file of contact predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
- Import to GREMLIN BETA - features includes ability to upload PDB and latest P(contact) calculation based on eLife 2015 fitting to PDB data.
GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled Score > 1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-position alignment confidence. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | M | Cov | P(%) | HHΔ | |
| 2vsqA | 1 | 0.9798 | 100 | 0.141 | Contact Map |
| 4dg8A | 1 | 0.4904 | 100 | 0.519 | Contact Map |
| 1amuA | 2 | 0.4938 | 100 | 0.556 | Contact Map |
| 4iz6A | 2 | 0.4972 | 100 | 0.56 | Contact Map |
| 3tsyA | 1 | 0.4556 | 100 | 0.562 | Contact Map |
| 4d4iA | 1 | 0 | 100 | 0.567 | Contact Map |
| 3wvnA | 2 | 0.4252 | 100 | 0.568 | Contact Map |
| 4gr5A | 4 | 0.5141 | 100 | 0.569 | Contact Map |
| 3vnrA | 1 | 0.4792 | 100 | 0.57 | Contact Map |
| 3g7sA | 2 | 0.4826 | 100 | 0.571 | Contact Map |
Cov = coverage of hit
P(%) = probability
Sequence Conservation (Image Generated using WebLogo v3)