| Janice Reimer |
| ID: | 1502898977 |
Query Sequence |
Download Alignment We filter this alignment to remove positions that have > 75% gaps before running GREMLIN. |
| Length: | 840 (827) | ||
| Sequences: | 12852 (10562.8) | ||
| Seq/Len: | 15.541 | ||
| Nf(neff/√len): | 367.3 |
Jackhmmer Results: (2016_04)
Sequences per length for each position, BEFORE the coverage/gap filter was applied
Legend: Dots above the red line, indicates positions where there is > 5 sequences per length (if visible, green bar = 20 seq/len). Point of this graphic is to give you an idea if resubmitting a sub-portion of your sequence might help increase the overall Seq/Len (which after applying the coverage filter is at: 15.541).
Sequences per length for each position, AFTER the coverage/gap filter was applied
Residue pairs sorted by coevolution strength:
Legend: The darker and larger the blue dots, the higher strength in covariance. Below we provide the list of the top [1.5 x length] covarying residues with sequence seperation > 3. The i and j are positions as given in the input sequence.
| i | j | Scaled score | Prob |
| 159_L | 199_V | 4.771 | 1.00 |
| 235_V | 275_E | 4.127 | 1.00 |
| 612_D | 643_R | 3.261 | 1.00 |
| 105_S | 123_V | 3.031 | 1.00 |
| 173_R | 176_L | 3.017 | 1.00 |
| 200_R | 207_Q | 3.015 | 1.00 |
| 144_L | 160_Y | 2.788 | 1.00 |
| 143_V | 199_V | 2.750 | 1.00 |
| 340_D | 373_E | 2.651 | 1.00 |
| 156_A | 209_L | 2.627 | 1.00 |
| 65_A | 89_E | 2.607 | 1.00 |
| 337_G | 370_P | 2.605 | 1.00 |
| 162_G | 192_L | 2.515 | 1.00 |
| 120_T | 141_V | 2.514 | 1.00 |
| 751_H | 755_R | 2.449 | 1.00 |
| 8_R | 33_T | 2.398 | 1.00 |
| 353_F | 362_G | 2.384 | 1.00 |
| 402_G | 416_P | 2.378 | 1.00 |
| 327_R | 349_E | 2.376 | 1.00 |
| 50_A | 54_A | 2.370 | 1.00 |
| 812_R | 837_N | 2.326 | 1.00 |
| 61_Q | 118_W | 2.321 | 1.00 |
| 453_D | 456_A | 2.310 | 1.00 |
| 122_S | 131_T | 2.309 | 1.00 |
| 398_N | 401_A | 2.297 | 1.00 |
| 598_A | 655_L | 2.297 | 1.00 |
| 259_V | 289_I | 2.289 | 1.00 |
| 141_V | 161_L | 2.252 | 1.00 |
| 537_A | 669_H | 2.243 | 1.00 |
| 389_G | 462_M | 2.224 | 1.00 |
| 392_L | 498_L | 2.213 | 1.00 |
| 390_D | 394_R | 2.167 | 1.00 |
| 232_L | 257_G | 2.156 | 1.00 |
| 257_G | 289_I | 2.140 | 1.00 |
| 742_L | 758_L | 2.140 | 1.00 |
| 216_V | 225_L | 2.137 | 1.00 |
| 324_D | 350_G | 2.124 | 1.00 |
| 156_A | 198_L | 2.123 | 1.00 |
| 348_Q | 351_M | 2.118 | 1.00 |
| 145_D | 149_R | 2.115 | 1.00 |
| 337_G | 374_F | 2.076 | 1.00 |
| 7_D | 83_R | 2.076 | 1.00 |
| 600_W | 689_T | 2.047 | 1.00 |
| 329_A | 332_E | 2.033 | 1.00 |
| 19_I | 61_Q | 2.030 | 1.00 |
| 603_A | 764_I | 2.027 | 1.00 |
| 334_L | 374_F | 2.020 | 1.00 |
| 229_E | 243_A | 2.015 | 1.00 |
| 140_H | 162_G | 2.007 | 1.00 |
| 260_V | 295_L | 1.998 | 1.00 |
| 61_Q | 109_V | 1.986 | 1.00 |
| 152_P | 155_V | 1.977 | 1.00 |
| 119_A | 161_L | 1.974 | 1.00 |
| 616_G | 687_F | 1.969 | 1.00 |
| 35_V | 51_L | 1.967 | 1.00 |
| 35_V | 57_A | 1.956 | 1.00 |
| 8_R | 57_A | 1.940 | 1.00 |
| 650_E | 658_R | 1.930 | 1.00 |
| 22_L | 118_W | 1.928 | 1.00 |
| 567_V | 751_H | 1.922 | 1.00 |
| 395_R | 494_E | 1.922 | 1.00 |
| 577_I | 766_E | 1.911 | 1.00 |
| 51_L | 55_S | 1.907 | 1.00 |
| 44_D | 47_A | 1.906 | 1.00 |
| 258_Y | 309_P | 1.903 | 1.00 |
| 109_V | 118_W | 1.901 | 1.00 |
| 396_Y | 494_E | 1.896 | 1.00 |
| 233_G | 240_R | 1.896 | 1.00 |
| 218_V | 245_V | 1.884 | 1.00 |
| 385_L | 495_F | 1.878 | 1.00 |
| 214_D | 305_R | 1.877 | 1.00 |
| 247_V | 253_G | 1.876 | 1.00 |
| 141_V | 159_L | 1.876 | 1.00 |
| 451_L | 461_R | 1.873 | 1.00 |
| 143_V | 206_L | 1.872 | 1.00 |
| 122_S | 205_V | 1.864 | 1.00 |
| 7_D | 58_T | 1.855 | 1.00 |
| 18_D | 112_P | 1.851 | 1.00 |
| 572_Q | 737_P | 1.849 | 1.00 |
| 328_R | 349_E | 1.848 | 1.00 |
| 68_R | 95_L | 1.846 | 1.00 |
| 341_V | 370_P | 1.831 | 1.00 |
| 627_E | 630_D | 1.828 | 1.00 |
| 61_Q | 87_G | 1.812 | 1.00 |
| 37_A | 51_L | 1.806 | 1.00 |
| 242_A | 295_L | 1.804 | 1.00 |
| 328_R | 332_E | 1.797 | 1.00 |
| 331_L | 349_E | 1.795 | 1.00 |
| 612_D | 645_R | 1.786 | 1.00 |
| 13_T | 19_I | 1.781 | 1.00 |
| 174_P | 178_V | 1.772 | 1.00 |
| 27_P | 32_A | 1.770 | 1.00 |
| 292_L | 295_L | 1.765 | 1.00 |
| 234_S | 279_L | 1.764 | 1.00 |
| 755_R | 759_S | 1.754 | 1.00 |
| 384_S | 499_Y | 1.750 | 1.00 |
| 381_D | 384_S | 1.744 | 1.00 |
| 22_L | 61_Q | 1.740 | 1.00 |
| 23_E | 61_Q | 1.737 | 1.00 |
| 184_D | 190_A | 1.737 | 1.00 |
| 392_L | 495_F | 1.734 | 1.00 |
| 140_H | 184_D | 1.733 | 1.00 |
| 381_D | 499_Y | 1.730 | 1.00 |
| 47_A | 50_A | 1.726 | 1.00 |
| 742_L | 754_A | 1.722 | 1.00 |
| 158_E | 194_R | 1.720 | 1.00 |
| 38_D | 41_T | 1.715 | 1.00 |
| 92_P | 95_L | 1.714 | 1.00 |
| 352_Y | 355_S | 1.713 | 1.00 |
| 574_E | 577_I | 1.710 | 1.00 |
| 12_V | 63_T | 1.699 | 1.00 |
| 567_V | 746_P | 1.699 | 1.00 |
| 814_R | 818_T | 1.682 | 1.00 |
| 60_M | 82_V | 1.678 | 1.00 |
| 259_V | 291_V | 1.677 | 1.00 |
| 462_M | 476_F | 1.649 | 1.00 |
| 167_V | 181_F | 1.644 | 1.00 |
| 651_E | 654_A | 1.643 | 1.00 |
| 153_E | 201_R | 1.642 | 1.00 |
| 330_R | 333_S | 1.642 | 1.00 |
| 115_A | 166_V | 1.640 | 1.00 |
| 544_Y | 662_E | 1.627 | 1.00 |
| 493_A | 631_R | 1.620 | 1.00 |
| 491_M | 633_V | 1.619 | 1.00 |
| 594_T | 660_F | 1.613 | 1.00 |
| 176_L | 180_R | 1.612 | 1.00 |
| 231_A | 279_L | 1.612 | 1.00 |
| 606_A | 760_R | 1.604 | 1.00 |
| 478_Q | 482_L | 1.600 | 1.00 |
| 243_A | 257_G | 1.594 | 1.00 |
| 115_A | 119_A | 1.590 | 1.00 |
| 134_Q | 205_V | 1.584 | 1.00 |
| 87_G | 118_W | 1.580 | 1.00 |
| 384_S | 503_R | 1.579 | 1.00 |
| 273_R | 289_I | 1.578 | 1.00 |
| 184_D | 192_L | 1.577 | 1.00 |
| 478_Q | 483_T | 1.571 | 1.00 |
| 834_A | 838_T | 1.570 | 1.00 |
| 386_R | 390_D | 1.567 | 1.00 |
| 602_L | 764_I | 1.566 | 1.00 |
| 607_V | 760_R | 1.565 | 1.00 |
| 41_T | 47_A | 1.562 | 1.00 |
| 385_L | 474_L | 1.560 | 1.00 |
| 231_A | 276_I | 1.555 | 1.00 |
| 323_V | 346_P | 1.552 | 1.00 |
| 624_P | 628_G | 1.551 | 1.00 |
| 143_V | 159_L | 1.551 | 1.00 |
| 93_Q | 97_D | 1.547 | 1.00 |
| 540_S | 544_Y | 1.542 | 1.00 |
| 13_T | 61_Q | 1.539 | 1.00 |
| 141_V | 199_V | 1.524 | 1.00 |
| 327_R | 331_L | 1.521 | 1.00 |
| 7_D | 59_V | 1.516 | 1.00 |
| 7_D | 32_A | 1.511 | 1.00 |
| 388_A | 499_Y | 1.510 | 1.00 |
| 258_Y | 308_L | 1.510 | 1.00 |
| 218_V | 223_I | 1.506 | 1.00 |
| 242_A | 303_V | 1.504 | 1.00 |
| 231_A | 234_S | 1.501 | 1.00 |
| 814_R | 817_A | 1.501 | 1.00 |
| 585_A | 595_V | 1.498 | 1.00 |
| 67_W | 84_A | 1.498 | 1.00 |
| 187_L | 190_A | 1.498 | 1.00 |
| 335_S | 347_L | 1.495 | 1.00 |
| 402_G | 457_P | 1.492 | 1.00 |
| 571_V | 740_L | 1.489 | 1.00 |
| 39_R | 42_V | 1.487 | 1.00 |
| 148_L | 160_Y | 1.485 | 1.00 |
| 258_Y | 311_T | 1.483 | 1.00 |
| 11_A | 23_E | 1.483 | 1.00 |
| 67_W | 86_V | 1.479 | 1.00 |
| 10_V | 57_A | 1.478 | 1.00 |
| 805_G | 813_E | 1.472 | 1.00 |
| 601_G | 644_V | 1.471 | 1.00 |
| 115_A | 161_L | 1.462 | 1.00 |
| 256_H | 290_T | 1.456 | 1.00 |
| 19_I | 118_W | 1.445 | 1.00 |
| 558_G | 562_R | 1.444 | 1.00 |
| 439_E | 442_A | 1.441 | 1.00 |
| 22_L | 109_V | 1.439 | 1.00 |
| 247_V | 250_A | 1.436 | 1.00 |
| 427_D | 466_W | 1.431 | 1.00 |
| 750_P | 753_V | 1.431 | 1.00 |
| 391_A | 394_R | 1.430 | 1.00 |
| 466_W | 472_A | 1.429 | 1.00 |
| 818_T | 821_E | 1.429 | 1.00 |
| 12_V | 62_A | 1.428 | 1.00 |
| 335_S | 349_E | 1.421 | 1.00 |
| 245_V | 253_G | 1.420 | 1.00 |
| 132_I | 208_F | 1.420 | 1.00 |
| 333_S | 336_P | 1.415 | 1.00 |
| 295_L | 303_V | 1.412 | 1.00 |
| 19_I | 87_G | 1.411 | 1.00 |
| 233_G | 241_A | 1.411 | 1.00 |
| 744_N | 754_A | 1.410 | 1.00 |
| 215_Q | 224_E | 1.408 | 1.00 |
| 338_W | 362_G | 1.406 | 0.99 |
| 85_L | 109_V | 1.406 | 0.99 |
| 332_E | 336_P | 1.405 | 0.99 |
| 239_F | 262_E | 1.397 | 0.99 |
| 221_F | 283_H | 1.393 | 0.99 |
| 10_V | 37_A | 1.392 | 0.99 |
| 403_F | 482_L | 1.388 | 0.99 |
| 268_D | 271_L | 1.387 | 0.99 |
| 27_P | 34_V | 1.382 | 0.99 |
| 304_D | 307_A | 1.381 | 0.99 |
| 404_T | 414_F | 1.381 | 0.99 |
| 10_V | 52_I | 1.380 | 0.99 |
| 48_L | 66_L | 1.367 | 0.99 |
| 198_L | 212_A | 1.363 | 0.99 |
| 398_N | 522_F | 1.363 | 0.99 |
| 652_I | 768_M | 1.360 | 0.99 |
| 19_I | 22_L | 1.360 | 0.99 |
| 569_T | 755_R | 1.350 | 0.99 |
| 483_T | 633_V | 1.349 | 0.99 |
| 160_Y | 182_V | 1.341 | 0.99 |
| 539_S | 543_D | 1.340 | 0.99 |
| 506_G | 509_P | 1.339 | 0.99 |
| 56_D | 81_M | 1.336 | 0.99 |
| 143_V | 151_V | 1.336 | 0.99 |
| 465_V | 475_V | 1.334 | 0.99 |
| 8_R | 35_V | 1.333 | 0.99 |
| 729_V | 740_L | 1.333 | 0.99 |
| 199_V | 208_F | 1.332 | 0.99 |
| 762_I | 766_E | 1.332 | 0.99 |
| 160_Y | 194_R | 1.331 | 0.99 |
| 145_D | 151_V | 1.329 | 0.99 |
| 275_E | 279_L | 1.322 | 0.99 |
| 775_T | 778_D | 1.319 | 0.99 |
| 91_L | 108_N | 1.317 | 0.99 |
| 558_G | 750_P | 1.315 | 0.99 |
| 99_L | 106_V | 1.309 | 0.99 |
| 540_S | 666_L | 1.304 | 0.99 |
| 107_R | 123_V | 1.302 | 0.99 |
| 538_L | 542_K | 1.302 | 0.99 |
| 23_E | 118_W | 1.298 | 0.99 |
| 142_R | 184_D | 1.294 | 0.99 |
| 61_Q | 64_P | 1.289 | 0.99 |
| 12_V | 66_L | 1.289 | 0.99 |
| 87_G | 116_T | 1.284 | 0.99 |
| 557_T | 753_V | 1.279 | 0.99 |
| 142_R | 186_S | 1.279 | 0.99 |
| 324_D | 349_E | 1.279 | 0.99 |
| 9_I | 27_P | 1.278 | 0.99 |
| 464_L | 472_A | 1.277 | 0.99 |
| 749_I | 754_A | 1.276 | 0.99 |
| 261_P | 291_V | 1.273 | 0.99 |
| 120_T | 206_L | 1.273 | 0.99 |
| 661_R | 665_S | 1.272 | 0.99 |
| 142_R | 145_D | 1.272 | 0.99 |
| 604_L | 689_T | 1.269 | 0.99 |
| 60_M | 84_A | 1.266 | 0.99 |
| 328_R | 331_L | 1.264 | 0.99 |
| 385_L | 499_Y | 1.264 | 0.99 |
| 141_V | 144_L | 1.262 | 0.99 |
| 600_W | 691_Y | 1.260 | 0.99 |
| 52_I | 81_M | 1.255 | 0.99 |
| 246_R | 310_D | 1.251 | 0.99 |
| 369_Q | 373_E | 1.250 | 0.99 |
| 200_R | 209_L | 1.241 | 0.98 |
| 820_D | 834_A | 1.240 | 0.98 |
| 558_G | 561_G | 1.238 | 0.98 |
| 68_R | 92_P | 1.235 | 0.98 |
| 109_V | 121_S | 1.233 | 0.98 |
| 273_R | 277_A | 1.222 | 0.98 |
| 72_E | 98_D | 1.220 | 0.98 |
| 225_L | 243_A | 1.220 | 0.98 |
| 547_D | 643_R | 1.219 | 0.98 |
| 141_V | 145_D | 1.219 | 0.98 |
| 559_S | 562_R | 1.219 | 0.98 |
| 382_V | 386_R | 1.217 | 0.98 |
| 537_A | 671_H | 1.210 | 0.98 |
| 566_P | 743_E | 1.209 | 0.98 |
| 727_L | 742_L | 1.207 | 0.98 |
| 18_D | 117_V | 1.206 | 0.98 |
| 142_R | 192_L | 1.205 | 0.98 |
| 87_G | 109_V | 1.203 | 0.98 |
| 391_A | 503_R | 1.202 | 0.98 |
| 61_Q | 66_L | 1.199 | 0.98 |
| 131_T | 205_V | 1.197 | 0.98 |
| 226_G | 229_E | 1.195 | 0.98 |
| 64_P | 67_W | 1.194 | 0.98 |
| 572_Q | 739_A | 1.194 | 0.98 |
| 388_A | 495_F | 1.191 | 0.98 |
| 12_V | 118_W | 1.191 | 0.98 |
| 11_A | 36_I | 1.190 | 0.98 |
| 21_A | 117_V | 1.185 | 0.98 |
| 596_V | 738_M | 1.184 | 0.98 |
| 600_W | 727_L | 1.184 | 0.98 |
| 552_T | 555_G | 1.182 | 0.98 |
| 135_P | 141_V | 1.180 | 0.98 |
| 575_Q | 737_P | 1.179 | 0.98 |
| 23_E | 109_V | 1.179 | 0.98 |
| 140_H | 190_A | 1.177 | 0.98 |
| 397_P | 400_R | 1.171 | 0.98 |
| 335_S | 338_W | 1.170 | 0.97 |
| 329_A | 333_S | 1.160 | 0.97 |
| 86_V | 91_L | 1.159 | 0.97 |
| 388_A | 498_L | 1.156 | 0.97 |
| 565_L | 747_D | 1.155 | 0.97 |
| 61_Q | 117_V | 1.154 | 0.97 |
| 543_D | 546_A | 1.148 | 0.97 |
| 160_Y | 192_L | 1.144 | 0.97 |
| 657_G | 661_R | 1.143 | 0.97 |
| 597_S | 615_F | 1.141 | 0.97 |
| 10_V | 51_L | 1.140 | 0.97 |
| 22_L | 87_G | 1.139 | 0.97 |
| 323_V | 348_Q | 1.139 | 0.97 |
| 12_V | 37_A | 1.139 | 0.97 |
| 539_S | 542_K | 1.138 | 0.97 |
| 460_I | 478_Q | 1.137 | 0.97 |
| 401_A | 413_Q | 1.135 | 0.97 |
| 448_F | 463_V | 1.134 | 0.97 |
| 335_S | 339_Q | 1.132 | 0.97 |
| 597_S | 691_Y | 1.131 | 0.97 |
| 326_D | 349_E | 1.130 | 0.97 |
| 380_V | 385_L | 1.129 | 0.97 |
| 557_T | 561_G | 1.127 | 0.97 |
| 806_S | 809_A | 1.123 | 0.97 |
| 176_L | 179_A | 1.123 | 0.97 |
| 822_T | 830_T | 1.123 | 0.97 |
| 96_A | 106_V | 1.122 | 0.97 |
| 692_V | 695_N | 1.121 | 0.97 |
| 533_D | 536_D | 1.116 | 0.96 |
| 20_A | 24_L | 1.115 | 0.96 |
| 460_I | 476_F | 1.114 | 0.96 |
| 214_D | 229_E | 1.114 | 0.96 |
| 229_E | 305_R | 1.113 | 0.96 |
| 162_G | 190_A | 1.112 | 0.96 |
| 811_L | 815_A | 1.112 | 0.96 |
| 275_E | 278_R | 1.110 | 0.96 |
| 64_P | 95_L | 1.110 | 0.96 |
| 194_R | 212_A | 1.109 | 0.96 |
| 144_L | 192_L | 1.109 | 0.96 |
| 401_A | 415_V | 1.109 | 0.96 |
| 201_R | 206_L | 1.104 | 0.96 |
| 391_A | 498_L | 1.104 | 0.96 |
| 90_A | 208_F | 1.103 | 0.96 |
| 721_T | 726_T | 1.103 | 0.96 |
| 493_A | 497_A | 1.101 | 0.96 |
| 425_E | 466_W | 1.098 | 0.96 |
| 426_I | 463_V | 1.097 | 0.96 |
| 122_S | 125_T | 1.097 | 0.96 |
| 258_Y | 312_A | 1.095 | 0.96 |
| 120_T | 132_I | 1.093 | 0.96 |
| 119_A | 141_V | 1.091 | 0.96 |
| 182_V | 192_L | 1.091 | 0.96 |
| 599_A | 765_L | 1.088 | 0.96 |
| 538_L | 672_L | 1.087 | 0.96 |
| 235_V | 272_V | 1.086 | 0.96 |
| 136_W | 139_V | 1.084 | 0.96 |
| 344_L | 347_L | 1.084 | 0.96 |
| 326_D | 331_L | 1.083 | 0.96 |
| 584_L | 595_V | 1.082 | 0.96 |
| 570_R | 741_T | 1.082 | 0.96 |
| 62_A | 67_W | 1.079 | 0.95 |
| 91_L | 96_A | 1.079 | 0.95 |
| 71_T | 99_L | 1.078 | 0.95 |
| 813_E | 817_A | 1.078 | 0.95 |
| 596_V | 691_Y | 1.078 | 0.95 |
| 487_S | 633_V | 1.076 | 0.95 |
| 413_Q | 416_P | 1.076 | 0.95 |
| 35_V | 55_S | 1.072 | 0.95 |
| 600_W | 761_T | 1.072 | 0.95 |
| 20_A | 23_E | 1.070 | 0.95 |
| 653_S | 773_T | 1.070 | 0.95 |
| 218_V | 253_G | 1.069 | 0.95 |
| 598_A | 659_L | 1.068 | 0.95 |
| 32_A | 58_T | 1.067 | 0.95 |
| 63_T | 118_W | 1.063 | 0.95 |
| 11_A | 34_V | 1.063 | 0.95 |
| 142_R | 162_G | 1.061 | 0.95 |
| 532_A | 535_T | 1.060 | 0.95 |
| 62_A | 66_L | 1.060 | 0.95 |
| 459_L | 482_L | 1.059 | 0.95 |
| 67_W | 99_L | 1.058 | 0.95 |
| 485_G | 489_T | 1.058 | 0.95 |
| 756_D | 760_R | 1.058 | 0.95 |
| 19_I | 109_V | 1.057 | 0.95 |
| 338_W | 370_P | 1.056 | 0.95 |
| 26_C | 118_W | 1.053 | 0.95 |
| 759_S | 762_I | 1.052 | 0.95 |
| 571_V | 762_I | 1.051 | 0.94 |
| 678_Q | 681_A | 1.050 | 0.94 |
| 570_R | 739_A | 1.044 | 0.94 |
| 535_T | 538_L | 1.044 | 0.94 |
| 156_A | 212_A | 1.043 | 0.94 |
| 326_D | 335_S | 1.041 | 0.94 |
| 13_T | 23_E | 1.039 | 0.94 |
| 336_P | 340_D | 1.039 | 0.94 |
| 537_A | 673_G | 1.039 | 0.94 |
| 723_Y | 731_P | 1.036 | 0.94 |
| 91_L | 106_V | 1.036 | 0.94 |
| 614_V | 641_P | 1.035 | 0.94 |
| 603_A | 761_T | 1.035 | 0.94 |
| 556_G | 561_G | 1.035 | 0.94 |
| 100_V | 126_T | 1.033 | 0.94 |
| 42_V | 66_L | 1.032 | 0.94 |
| 614_V | 643_R | 1.030 | 0.94 |
| 363_T | 366_Y | 1.029 | 0.94 |
| 161_L | 195_T | 1.029 | 0.94 |
| 616_G | 723_Y | 1.028 | 0.94 |
| 527_R | 531_E | 1.028 | 0.94 |
| 37_A | 48_L | 1.027 | 0.94 |
| 588_S | 771_S | 1.026 | 0.94 |
| 136_W | 165_Q | 1.019 | 0.93 |
| 393_L | 460_I | 1.018 | 0.93 |
| 582_R | 731_P | 1.016 | 0.93 |
| 544_Y | 665_S | 1.015 | 0.93 |
| 809_A | 812_R | 1.014 | 0.93 |
| 603_A | 760_R | 1.013 | 0.93 |
| 215_Q | 222_R | 1.010 | 0.93 |
| 554_V | 557_T | 1.008 | 0.93 |
| 108_N | 132_I | 1.006 | 0.93 |
| 462_M | 474_L | 1.006 | 0.93 |
| 22_L | 117_V | 1.006 | 0.93 |
| 619_V | 623_S | 1.006 | 0.93 |
| 496_F | 500_E | 1.005 | 0.93 |
| 723_Y | 727_L | 1.005 | 0.93 |
| 721_T | 724_A | 1.003 | 0.93 |
| 728_D | 731_P | 1.002 | 0.92 |
| 142_R | 146_D | 1.001 | 0.92 |
Prob = P(contact | scaled_score, seq/len).
Scaled Score = (raw_score/average(raw_scores)).
- Text file of contact predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
- See coupling matrix (for protein design or mutagenesis)
- Import to GREMLIN BETA - features includes ability to upload PDB and latest P(contact) calculation based on eLife 2015 fitting to PDB data.
GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled Score > 1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-position alignment confidence. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | M | Cov | P(%) | HHΔ | |
| 2vsqA | 1 | 0.7131 | 100 | 0.544 | Contact Map |
| 4dg8A | 1 | 0.3607 | 100 | 0.56 | Contact Map |
| 4iz6A | 2 | 0.4583 | 100 | 0.58 | Contact Map |
| 4r0mB | 2 | 0.4607 | 100 | 0.586 | Contact Map |
| 4d4iA | 1 | 0 | 100 | 0.612 | Contact Map |
| 1amuA | 2 | 0.3667 | 100 | 0.613 | Contact Map |
| 2jgpA | 1 | 0.5131 | 100 | 0.639 | Contact Map |
| 3g7sA | 2 | 0.3214 | 100 | 0.645 | Contact Map |
| 3etcA | 2 | 0.344 | 100 | 0.648 | Contact Map |
| 3e7wA | 1 | 0.3762 | 100 | 0.648 | Contact Map |
Cov = coverage of hit
P(%) = probability
Sequence Conservation (Image Generated using WebLogo v3)